# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- COX1 PF00115.20 ORY08684.1 - 1.4e-48 165.9 18.4 1.4e-48 165.9 18.4 1.7 1 1 1 2 2 2 2 Cytochrome C and Quinol oxidase polypeptide I CARD PF00619.21 ORY08967.1 - 0.031 14.3 0.1 0.065 13.3 0.1 1.5 1 0 0 1 1 1 0 Caspase recruitment domain DUF3450 PF11932.8 ORY08968.1 - 0.00077 18.8 1.2 0.001 18.4 1.0 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) Nsp1_C PF05064.13 ORY08968.1 - 0.00095 19.0 1.0 0.0011 18.8 1.0 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region ZapB PF06005.12 ORY08968.1 - 0.0011 19.4 4.4 0.0014 19.0 4.4 1.3 1 1 0 1 1 1 1 Cell division protein ZapB BLOC1_2 PF10046.9 ORY08968.1 - 0.0022 18.2 0.8 0.0029 17.9 0.8 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 ORY08968.1 - 0.0029 17.5 0.9 0.0033 17.3 0.9 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 BST2 PF16716.5 ORY08968.1 - 0.0042 17.6 2.2 0.0053 17.3 2.2 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 GAS PF13851.6 ORY08968.1 - 0.0057 16.0 2.8 0.0064 15.9 2.8 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding YabA PF06156.13 ORY08968.1 - 0.018 15.6 1.2 0.022 15.4 1.2 1.2 1 0 0 1 1 1 0 Initiation control protein YabA CCDC92 PF14916.6 ORY08968.1 - 0.019 14.7 3.5 0.034 13.9 3.3 1.6 1 1 0 1 1 1 0 Coiled-coil domain of unknown function Cluap1 PF10234.9 ORY08968.1 - 0.019 14.4 1.4 0.02 14.3 1.4 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Herpes_UL6 PF01763.16 ORY08968.1 - 0.019 13.5 1.5 0.02 13.5 1.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like HlyD_D23 PF16576.5 ORY08968.1 - 0.027 13.7 1.0 0.029 13.6 1.0 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion TMF_DNA_bd PF12329.8 ORY08968.1 - 0.034 14.1 1.1 0.034 14.1 1.1 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Rab_bind PF16704.5 ORY08968.1 - 0.034 14.2 0.3 2.8 8.1 0.1 2.3 1 1 1 2 2 2 0 Rab binding domain Sec34 PF04136.15 ORY08968.1 - 0.035 14.0 1.3 0.039 13.8 1.3 1.1 1 0 0 1 1 1 0 Sec34-like family APG6_N PF17675.1 ORY08968.1 - 0.046 14.3 2.7 0.062 13.8 2.7 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF948 PF06103.11 ORY08968.1 - 0.077 13.3 0.4 0.11 12.8 0.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 ORY08968.1 - 0.13 12.5 2.9 0.52 10.5 2.8 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 ORY08968.1 - 0.14 12.4 1.7 0.27 11.5 1.7 1.5 1 0 0 1 1 1 0 Haemolysin XhlA USP8_interact PF08941.10 ORY08968.1 - 0.15 11.9 1.9 0.18 11.6 1.9 1.1 1 0 0 1 1 1 0 USP8 interacting SlyX PF04102.12 ORY08968.1 - 0.27 11.9 4.6 2.1 9.0 4.6 2.1 1 1 0 1 1 1 0 SlyX DivIC PF04977.15 ORY08968.1 - 0.77 9.6 4.7 3.7 7.4 4.7 2.0 1 1 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 ORY08968.1 - 0.98 9.6 3.9 3.9 7.6 1.2 2.3 1 1 1 2 2 2 0 Basic region leucine zipper RNase_H PF00075.24 ORY09038.1 - 0.0068 16.6 0.4 0.1 12.8 0.0 2.9 1 1 0 2 2 2 1 RNase H DDE_3 PF13358.6 ORY09559.1 - 0.0046 16.7 0.1 0.0062 16.3 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.6 ORY09560.1 - 0.086 12.6 0.0 0.096 12.4 0.0 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease ZipA_C PF04354.13 ORY09560.1 - 0.17 11.7 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 ZipA, C-terminal FtsZ-binding domain DUF4698 PF15769.5 ORY09697.1 - 1.3e-07 31.1 7.2 1.9e-06 27.3 4.8 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4698) Syntaxin-18_N PF10496.9 ORY09697.1 - 0.036 14.3 0.3 0.093 13.0 0.3 1.8 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus CLP1_P PF16575.5 ORY09698.1 - 1.1e-38 132.9 0.0 5.4e-38 130.7 0.0 2.0 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 ORY09698.1 - 0.051 13.3 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ORY09698.1 - 0.063 13.5 0.0 0.27 11.5 0.0 2.1 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 ORY09698.1 - 0.1 13.0 0.0 0.59 10.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 ORY09698.1 - 0.2 11.7 0.0 0.4 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Abhydrolase_2 PF02230.16 ORY09702.1 - 8.2e-11 42.1 0.0 9.3e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase LIP PF03583.14 ORY09702.1 - 0.0052 16.1 0.0 2.4 7.4 0.0 2.1 2 0 0 2 2 2 2 Secretory lipase Abhydrolase_5 PF12695.7 ORY09702.1 - 0.022 14.5 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Palm_thioest PF02089.15 ORY09702.1 - 0.023 14.5 0.0 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DLH PF01738.18 ORY09702.1 - 0.045 13.3 0.0 0.058 12.9 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 ORY09702.1 - 0.069 13.7 0.0 0.089 13.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY09702.1 - 0.082 12.2 0.2 1.7 7.8 0.0 2.0 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY09702.1 - 0.088 12.4 0.3 5.1 6.6 0.1 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 ORY09702.1 - 0.094 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Esterase PF00756.20 ORY09702.1 - 0.1 12.2 0.0 0.47 10.1 0.0 1.8 1 1 0 1 1 1 0 Putative esterase FSH1 PF03959.13 ORY09702.1 - 0.19 11.4 0.1 0.45 10.1 0.1 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) 7tm_3 PF00003.22 ORY09784.1 - 9.9e-31 107.3 26.6 1.6e-30 106.6 26.6 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR FLgD_tudor PF13861.6 ORY09784.1 - 0.019 15.2 0.0 1.7 8.9 0.0 3.8 2 1 0 2 2 2 0 FlgD Tudor-like domain COX4 PF02936.14 ORY09784.1 - 0.39 10.7 1.0 5.1 7.1 0.2 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase subunit IV FAM176 PF14851.6 ORY09785.1 - 0.035 13.8 1.4 0.046 13.4 1.4 1.2 1 0 0 1 1 1 0 FAM176 family DUF2428 PF10350.9 ORY09785.1 - 0.084 12.1 0.3 0.088 12.0 0.3 1.1 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) Nop14 PF04147.12 ORY09785.1 - 0.14 10.4 6.6 0.15 10.3 6.6 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 ORY09785.1 - 0.2 9.7 12.4 0.22 9.6 12.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 ORY09785.1 - 0.21 10.9 7.8 0.22 10.8 7.8 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 ORY09785.1 - 0.25 11.4 8.8 0.071 13.1 3.8 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal E7 PF00527.18 ORY09785.1 - 1 9.6 3.7 1.7 8.9 3.7 1.4 1 0 0 1 1 1 0 E7 protein, Early protein DUF4611 PF15387.6 ORY09785.1 - 5.3 7.3 14.0 16 5.8 13.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) CDC45 PF02724.14 ORY09785.1 - 6.2 5.0 9.3 7.4 4.7 9.3 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 ORY09785.1 - 7.9 5.5 14.3 8.9 5.3 14.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cytochrom_B558a PF05038.13 ORY09871.1 - 0.00042 19.9 0.9 0.0011 18.6 0.9 1.7 1 1 0 1 1 1 1 Cytochrome Cytochrome b558 alpha-subunit JAB PF01398.21 ORY09944.1 - 2.9e-30 104.7 0.3 5e-30 103.9 0.3 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 ORY09944.1 - 1.2e-21 77.4 0.1 3.1e-21 76.1 0.0 1.7 2 0 0 2 2 2 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 ORY09944.1 - 0.0021 17.8 0.0 0.005 16.6 0.0 1.6 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 ORY09944.1 - 0.067 13.2 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) LRR_6 PF13516.6 ORY09945.1 - 0.032 14.3 0.1 26 5.2 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 ORY09945.1 - 0.32 11.5 7.7 6.9 7.2 0.7 3.3 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) DNA_pol_A_exo1 PF01612.20 ORY10084.1 - 0.0027 17.4 0.0 0.0033 17.1 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease zf-C2H2 PF00096.26 ORY10085.1 - 0.065 13.7 11.0 11 6.7 2.0 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type OrsD PF12013.8 ORY10085.1 - 0.23 11.9 5.8 1.1 9.7 1.8 2.7 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 ORY10085.1 - 6.1 8.0 12.0 28 5.9 2.4 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 ORY10085.1 - 8.3 6.1 8.7 6.5 6.5 1.3 2.5 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain SPATA1_C PF15743.5 ORY10226.1 - 0.0024 18.0 3.1 0.0037 17.3 3.1 1.2 1 0 0 1 1 1 1 Spermatogenesis-associated C-terminus DUF3015 PF11220.8 ORY10226.1 - 0.032 14.1 1.4 0.064 13.1 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) DUF4355 PF14265.6 ORY10226.1 - 0.17 12.2 7.7 0.31 11.3 7.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) TFIIA PF03153.13 ORY10226.1 - 0.42 10.6 13.2 0.49 10.3 13.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 ORY10226.1 - 0.44 9.9 3.6 0.66 9.3 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GET2 PF08690.10 ORY10226.1 - 6.9 6.2 9.6 6.9 6.3 3.6 2.3 2 0 0 2 2 2 0 GET complex subunit GET2 TMPIT PF07851.13 ORY10226.1 - 8 5.6 6.5 12 5.1 6.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein adh_short PF00106.25 ORY10826.1 - 2.9e-05 23.6 0.2 0.00034 20.1 0.0 2.1 1 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY10826.1 - 0.0086 15.6 0.1 0.03 13.9 0.0 1.7 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Pkinase PF00069.25 ORY10827.1 - 1.7e-12 47.2 0.0 3.1e-12 46.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 ORY10827.1 - 3.6e-06 26.0 0.0 5.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase CDK2AP PF09806.9 ORY10827.1 - 0.44 10.6 10.8 3.5 7.6 4.2 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Pkinase PF00069.25 ORY10828.1 - 1.9e-12 47.1 0.0 1.9e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY10828.1 - 1.7e-07 30.8 0.0 0.014 14.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY10828.1 - 0.00041 19.2 2.0 0.00071 18.5 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase U1snRNP70_N PF12220.8 ORY10828.1 - 0.072 13.7 0.4 0.28 11.8 0.0 2.2 2 1 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Homeodomain PF00046.29 ORY11172.1 - 0.0026 17.6 0.0 0.0071 16.2 0.0 1.7 1 0 0 1 1 1 1 Homeodomain DUF1936 PF09151.10 ORY11172.1 - 0.048 13.6 0.4 0.1 12.5 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) Pneumovirus_M2 PF06436.11 ORY11172.1 - 0.26 10.8 4.1 0.67 9.4 4.1 1.6 1 0 0 1 1 1 0 Pneumovirus matrix protein 2 (M2) Ureide_permease PF07168.11 ORY11172.1 - 4.9 5.8 5.2 10 4.8 5.2 1.4 1 0 0 1 1 1 0 Ureide permease COX1 PF00115.20 ORY11190.1 - 6.8e-10 38.4 3.8 7.4e-10 38.2 3.8 1.0 1 0 0 1 1 1 1 Cytochrome C and Quinol oxidase polypeptide I CitT PF12431.8 ORY11387.1 - 0.18 12.2 0.1 0.41 11.1 0.1 1.6 1 0 0 1 1 1 0 Transcriptional regulator COX3 PF00510.18 ORY11460.1 - 1.9e-89 299.9 29.7 2.2e-89 299.7 29.7 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit III NADHdh PF00146.21 ORY11461.1 - 1.1e-76 258.1 27.1 1.7e-76 257.4 27.1 1.3 1 1 0 1 1 1 1 NADH dehydrogenase Nucleotid_trans PF03407.16 ORY11478.1 - 1.6e-05 25.0 0.0 3.6e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Imm17 PF15562.6 ORY11478.1 - 0.21 11.5 6.1 2.4 8.1 0.4 2.6 2 0 0 2 2 2 0 Immunity protein 17 ESM4 PF15952.5 ORY11478.1 - 0.21 12.0 0.8 7.6 6.9 0.2 2.3 2 0 0 2 2 2 0 Enhancer of split M4 family PDR_assoc PF08370.11 ORY11478.1 - 0.23 11.2 6.8 0.38 10.5 0.4 2.9 3 0 0 3 3 3 0 Plant PDR ABC transporter associated zf-CCHC PF00098.23 ORY11946.1 - 1.1e-07 31.6 2.0 1.9e-07 30.9 2.0 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 ORY11946.1 - 0.0099 15.6 0.8 0.017 14.8 0.8 1.4 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 ORY11946.1 - 0.026 14.5 2.0 0.03 14.3 0.5 2.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 ORY11946.1 - 0.11 12.4 1.6 0.16 11.8 1.6 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF1764 PF08576.10 ORY11946.1 - 2.2 9.3 4.9 6 7.8 0.4 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) KxDL PF10241.9 ORY12163.1 - 0.11 12.8 0.1 0.11 12.8 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein Sel1 PF08238.12 ORY12164.1 - 2.4e-64 212.3 56.1 1.8e-10 41.2 4.3 8.5 8 1 0 8 8 7 7 Sel1 repeat Pkinase PF00069.25 ORY12164.1 - 8.3e-34 117.1 0.0 1.2e-33 116.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY12164.1 - 1.6e-29 103.0 0.0 2.7e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_12 PF13424.6 ORY12164.1 - 1.5e-07 31.6 21.0 0.34 11.2 2.7 7.3 3 1 4 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 ORY12164.1 - 1.3e-06 27.9 57.3 1.4 8.9 0.1 13.8 15 0 0 15 15 15 6 Tetratricopeptide repeat TPR_11 PF13414.6 ORY12164.1 - 0.00072 19.2 49.1 0.42 10.3 3.0 8.8 7 5 0 7 7 7 6 TPR repeat APH PF01636.23 ORY12164.1 - 0.0057 16.6 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family TPR_16 PF13432.6 ORY12164.1 - 0.035 14.8 20.9 0.96 10.2 2.6 5.3 2 1 4 6 6 6 0 Tetratricopeptide repeat Kinase-like PF14531.6 ORY12164.1 - 0.043 13.1 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like TPR_6 PF13174.6 ORY12164.1 - 0.38 11.5 28.3 41 5.1 0.1 8.3 8 1 1 9 9 8 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY12164.1 - 2.2 8.6 49.1 1.1 9.6 0.1 12.2 13 1 0 13 13 13 0 Tetratricopeptide repeat TB2_DP1_HVA22 PF03134.19 ORY12165.1 - 3.5e-27 94.1 5.5 3.5e-27 94.1 5.5 1.9 2 0 0 2 2 2 1 TB2/DP1, HVA22 family YkpC PF17447.2 ORY12486.1 - 0.69 10.8 0.1 0.69 10.8 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized YkpC-like DUF853 PF05872.12 ORY12487.1 - 3.4 6.2 5.8 7.5 5.0 5.8 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) RRM_1 PF00076.22 ORY12560.1 - 1.6e-41 140.0 0.1 6.8e-20 70.7 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY12560.1 - 5.8e-06 26.2 0.0 0.00087 19.2 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 ORY12560.1 - 6.4e-05 22.6 0.0 0.34 10.5 0.0 2.1 1 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 ORY12560.1 - 0.0002 21.2 0.0 0.0043 16.9 0.0 2.2 1 1 0 2 2 2 1 Domain of unknown function (DUF1866) RRM_7 PF16367.5 ORY12560.1 - 0.0009 19.3 0.0 0.23 11.6 0.0 2.6 2 1 0 2 2 2 1 RNA recognition motif RRM_3 PF08777.11 ORY12560.1 - 0.0012 18.8 0.5 0.52 10.4 0.0 2.4 2 1 0 2 2 2 2 RNA binding motif RRM_occluded PF16842.5 ORY12560.1 - 0.0096 15.8 0.0 2 8.3 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM PF05172.13 ORY12560.1 - 0.083 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif CytadhesinP1 PF12378.8 ORY12562.1 - 0.045 13.9 0.0 8.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Trypsin-sensitive surface-exposed protein SH3_1 PF00018.28 ORY12563.1 - 2.6e-08 33.4 0.0 3.6e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY12563.1 - 7.7e-07 28.9 0.0 1.3e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Phage_holin_3_6 PF07332.11 ORY12563.1 - 0.025 14.6 0.2 0.036 14.1 0.2 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III PhoD PF09423.10 ORY12564.1 - 1.6e-97 326.7 0.0 2e-97 326.4 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 ORY12564.1 - 4.2e-19 68.9 0.0 1.1e-18 67.5 0.0 1.8 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 ORY12564.1 - 0.0014 19.1 0.0 0.0039 17.7 0.0 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 ORY12564.1 - 0.0099 16.4 1.6 2.1 8.8 1.8 3.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Piwi PF02171.17 ORY12565.1 - 2.2e-14 53.4 0.6 1e-06 28.2 0.0 3.1 1 1 2 3 3 3 3 Piwi domain gag_pre-integrs PF13976.6 ORY12580.1 - 0.0012 18.7 0.5 0.004 17.0 0.5 2.0 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.26 ORY12580.1 - 0.0036 17.5 0.0 0.0086 16.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_2 PF14223.6 ORY12580.1 - 0.0061 16.2 0.2 0.013 15.2 0.2 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Peptidase_C2 PF00648.21 ORY12910.1 - 8.7e-09 34.8 0.0 4.2e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 Calpain family cysteine protease Pyr_redox_2 PF07992.14 ORY12911.1 - 1e-44 153.0 0.0 1.4e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY12911.1 - 9.1e-12 45.4 0.0 4.7e-11 43.1 0.1 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY12911.1 - 0.00038 19.8 0.0 0.21 10.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY12911.1 - 0.018 14.7 0.0 0.73 9.3 0.0 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase TrkA_TMD PF18613.1 ORY12911.1 - 0.083 12.3 1.1 0.2 11.1 1.1 1.6 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain NAD_binding_9 PF13454.6 ORY12911.1 - 0.1 12.5 0.0 3.3 7.7 0.0 2.7 2 1 1 3 3 3 0 FAD-NAD(P)-binding ArsA_ATPase PF02374.15 ORY12912.1 - 1.6e-110 369.1 0.2 1.8e-110 368.9 0.2 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 ORY12912.1 - 2.4e-12 47.1 0.0 6.5e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ORY12912.1 - 9e-11 41.9 0.0 1.5e-10 41.2 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 ORY12912.1 - 6.7e-06 25.8 0.0 1.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 ORY12912.1 - 5.1e-05 22.8 0.7 0.00054 19.5 0.0 2.2 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 ORY12912.1 - 0.00046 19.7 0.0 0.00097 18.7 0.0 1.5 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 ORY12912.1 - 0.004 16.8 0.1 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 ORY12912.1 - 0.012 15.4 0.0 0.034 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORY12912.1 - 0.059 12.9 0.2 0.13 11.9 0.2 1.7 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ORY12912.1 - 0.063 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Surp PF01805.20 ORY13333.1 - 2e-17 62.9 0.0 5e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 ORY13333.1 - 1.8e-12 46.9 0.0 9.4e-12 44.6 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_UL74 PF07982.12 ORY13333.1 - 0.0039 16.2 0.1 0.3 10.0 0.0 2.1 2 0 0 2 2 2 2 Herpes UL74 glycoproteins RRM_7 PF16367.5 ORY13333.1 - 0.029 14.5 0.0 0.065 13.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif Arm-DNA-bind_4 PF14657.6 ORY13333.1 - 0.055 13.2 1.4 12 5.7 1.5 3.1 2 1 1 3 3 3 0 Arm DNA-binding domain PRIMA1 PF16101.5 ORY13333.1 - 0.18 11.8 1.1 0.72 9.9 1.1 2.0 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 EF-hand_6 PF13405.6 ORY13334.1 - 6.7e-09 35.0 2.2 0.012 15.5 0.0 4.8 5 0 0 5 5 5 2 EF-hand domain EF-hand_7 PF13499.6 ORY13334.1 - 1.3e-08 35.2 7.3 0.8 10.2 0.0 5.4 5 0 0 5 5 5 4 EF-hand domain pair EF-hand_1 PF00036.32 ORY13334.1 - 1.5e-06 27.3 5.8 0.0036 16.7 0.0 4.5 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 ORY13334.1 - 7.9e-06 25.6 0.4 0.073 12.9 0.0 4.5 4 0 0 4 4 4 2 EF-hand domain pair RST PF12174.8 ORY13334.1 - 0.0047 16.8 15.7 0.31 11.0 0.2 5.0 6 0 0 6 6 6 2 RCD1-SRO-TAF4 (RST) plant domain EF-hand_11 PF08976.11 ORY13334.1 - 0.013 16.3 5.4 0.62 11.0 0.1 4.0 4 0 0 4 4 4 0 EF-hand domain SF3A3 PF16837.5 ORY13334.1 - 0.11 13.0 0.0 1.3 9.5 0.0 2.6 2 0 0 2 2 2 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 OrsD PF12013.8 ORY13666.1 - 0.04 14.4 5.5 0.24 11.9 2.6 2.7 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Zn_clus PF00172.18 ORY13669.1 - 2.9e-09 36.9 25.0 0.00018 21.6 10.5 2.6 1 1 1 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF829 PF05705.14 ORY13670.1 - 1.3e-25 90.7 0.0 1.8e-25 90.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Ribosomal_60s PF00428.19 ORY13671.1 - 1.6e-25 89.5 14.8 2.3e-25 89.0 14.8 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 ORY13671.1 - 0.062 11.8 0.6 0.078 11.4 0.6 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein MFS_1 PF07690.16 ORY13672.1 - 7.2e-26 90.9 28.1 7.2e-26 90.9 28.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_18 PF00704.28 ORY13789.1 - 3.4e-11 43.4 0.2 4.9e-11 42.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ETRAMP PF09716.10 ORY13789.1 - 0.0026 17.8 1.6 0.0049 16.9 1.6 1.5 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) kleA_kleC PF17383.2 ORY13981.1 - 0.017 15.4 0.4 0.017 15.4 0.4 2.6 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A DDR PF08841.10 ORY13981.1 - 0.21 10.5 1.4 0.37 9.7 1.4 1.4 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain tRNA-synt_1g PF09334.11 ORY14095.1 - 6.9 5.3 7.8 9.6 4.8 7.8 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) CDC50 PF03381.15 ORY14096.1 - 3.5e-52 177.7 4.1 7.9e-39 133.8 0.2 2.1 1 1 1 2 2 2 2 LEM3 (ligand-effect modulator 3) family / CDC50 family 60KD_IMP PF02096.20 ORY14096.1 - 0.034 14.1 1.3 0.094 12.6 0.2 2.0 1 1 1 2 2 2 0 60Kd inner membrane protein Dynein_C PF18199.1 ORY14233.1 - 5.1e-96 321.5 0.0 5.7e-96 321.3 0.0 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain PARP_reg PF02877.14 ORY14233.1 - 0.014 15.5 0.0 0.047 13.8 0.0 1.9 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain Ins_P5_2-kin PF06090.12 ORY14233.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.3 1 1 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase ATP-synt_C PF00137.21 ORY14353.1 - 2.4e-06 27.8 10.9 7.7e-06 26.2 10.9 1.7 1 1 0 1 1 1 1 ATP synthase subunit C LAGLIDADG_1 PF00961.19 ORY14354.1 - 1.3e-17 64.6 0.1 1.7e-17 64.3 0.1 1.2 1 0 0 1 1 1 1 LAGLIDADG endonuclease LAGLIDADG_2 PF03161.13 ORY14355.1 - 6.5e-33 114.1 0.1 7.6e-33 113.9 0.1 1.1 1 0 0 1 1 1 1 LAGLIDADG DNA endonuclease family OrfB_Zn_ribbon PF07282.11 ORY14364.1 - 0.00036 20.4 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 Putative transposase DNA-binding domain PAN_4 PF14295.6 ORY14491.1 - 4.3e-06 26.5 3.6 0.03 14.2 0.4 2.7 2 0 0 2 2 2 2 PAN domain PAN_1 PF00024.26 ORY14491.1 - 0.013 15.4 5.8 0.059 13.3 0.3 2.6 1 1 1 2 2 2 0 PAN domain PAN_3 PF08277.12 ORY14491.1 - 0.13 12.0 9.4 0.18 11.7 0.1 3.4 3 0 0 3 3 3 0 PAN-like domain NYN PF01936.18 ORY14738.1 - 5.3e-24 85.4 0.0 7.9e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 NYN domain Tlr3_TMD PF17968.1 ORY14857.1 - 0.075 13.2 1.3 0.16 12.1 1.3 1.6 1 0 0 1 1 1 0 Toll-like receptor 3 trans-membrane domain Zn_clus PF00172.18 ORY14969.1 - 0.0031 17.6 8.6 0.0043 17.1 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_4 PF13637.6 ORY15082.1 - 1.6e-28 98.7 0.1 1.1e-11 45.0 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY15082.1 - 8.4e-27 93.6 0.6 3.6e-17 62.7 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORY15082.1 - 1.2e-24 85.6 0.1 4.3e-06 26.9 0.1 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 ORY15082.1 - 4.9e-19 66.4 0.0 0.0002 21.6 0.0 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 ORY15082.1 - 1.6e-10 41.0 0.1 1.9e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) YfmQ PF10787.9 ORY15082.1 - 0.021 14.6 0.0 4.5 7.0 0.0 2.8 1 1 2 3 3 3 0 Uncharacterised protein from bacillus cereus group DUF4792 PF16040.5 ORY15082.1 - 0.045 13.7 0.0 7.3 6.6 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4792) Imm_superinfect PF14373.6 ORY15082.1 - 0.094 12.7 0.0 23 5.0 0.0 3.0 3 0 0 3 3 3 0 Superinfection immunity protein Ank_2 PF12796.7 ORY15083.1 - 2e-28 98.8 0.9 9.3e-13 48.6 0.2 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY15083.1 - 2.6e-27 94.8 0.2 9.7e-12 45.2 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY15083.1 - 4.6e-26 90.1 1.3 7e-06 26.3 0.1 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 ORY15083.1 - 1.5e-17 61.9 0.1 0.0032 17.8 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 ORY15083.1 - 4.4e-17 61.9 0.3 3.2e-08 33.7 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Imm_superinfect PF14373.6 ORY15083.1 - 0.00064 19.6 0.0 7.6 6.6 0.0 3.7 4 0 0 4 4 4 1 Superinfection immunity protein PEGA PF08308.11 ORY15083.1 - 0.0016 18.3 0.4 10 6.1 0.0 3.9 2 2 2 4 4 4 1 PEGA domain VWA_3_C PF18571.1 ORY15083.1 - 0.072 13.0 3.9 25 4.8 0.2 3.9 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain Ank_2 PF12796.7 ORY15084.1 - 3.1e-28 98.2 0.0 9.6e-15 54.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY15084.1 - 1.7e-24 85.8 0.0 3.8e-12 46.5 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY15084.1 - 1.6e-19 69.7 0.0 1.2e-07 31.9 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY15084.1 - 2.6e-18 65.6 0.0 5.4e-07 29.8 0.1 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 ORY15084.1 - 5.7e-18 63.1 0.0 2.1e-05 24.5 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat RVP PF00077.20 ORY15084.1 - 0.011 16.0 0.0 34 4.8 0.0 3.0 2 1 1 3 3 3 0 Retroviral aspartyl protease gag-asp_proteas PF13975.6 ORY15084.1 - 0.03 14.9 0.0 42 4.8 0.0 3.0 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease VWA_3_C PF18571.1 ORY15084.1 - 0.18 11.7 0.1 11 6.0 0.0 2.8 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain AAA_22 PF13401.6 ORY15085.1 - 3.1e-07 30.8 0.0 5.4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 ORY15085.1 - 3.4e-06 26.5 0.1 1.4e-05 24.5 0.1 1.8 1 1 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.6 ORY15085.1 - 3.7e-06 27.4 0.0 6.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 ORY15085.1 - 9.2e-06 25.7 0.9 0.00014 21.9 0.9 2.1 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea NACHT PF05729.12 ORY15085.1 - 0.0002 21.3 0.0 0.00064 19.7 0.0 1.8 1 1 0 1 1 1 1 NACHT domain NB-ARC PF00931.22 ORY15085.1 - 0.0035 16.6 0.0 0.0052 16.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_5 PF07728.14 ORY15085.1 - 0.0056 16.7 0.0 2.2 8.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA PF00004.29 ORY15085.1 - 0.013 15.9 0.0 1.8 9.0 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORY15085.1 - 0.13 12.7 0.0 0.42 11.0 0.0 1.8 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 ORY15085.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI EF-hand_7 PF13499.6 ORY15642.1 - 9.4e-19 67.6 13.4 6.5e-12 45.7 2.5 2.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY15642.1 - 4e-15 54.4 4.6 3e-06 26.7 0.0 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 ORY15642.1 - 5.4e-14 50.6 10.7 3.8e-05 22.9 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 ORY15642.1 - 2.1e-07 30.7 12.7 0.0041 16.9 0.3 3.9 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 ORY15642.1 - 1.4e-05 25.3 0.3 0.069 13.5 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 ORY15642.1 - 4.9e-05 22.6 5.4 0.0095 15.4 0.1 3.7 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 ORY15642.1 - 0.017 15.0 6.9 2.2 8.3 0.1 3.3 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORY15642.1 - 0.064 13.6 0.4 2.3 8.5 0.0 2.4 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DBI_PRT PF02277.17 ORY15643.1 - 4.9e-98 328.4 12.9 5.9e-98 328.1 12.9 1.0 1 0 0 1 1 1 1 Phosphoribosyltransferase Methyltransf_11 PF08241.12 ORY15644.1 - 1.8e-11 44.5 0.0 2.9e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY15644.1 - 5.5e-08 33.4 0.0 9.7e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY15644.1 - 7.3e-05 23.4 0.0 0.00015 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY15644.1 - 0.00012 22.0 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY15644.1 - 0.0011 18.8 0.0 0.0013 18.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY15644.1 - 0.0088 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 ORY15644.1 - 0.062 11.9 0.0 0.078 11.5 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.11 ORY15644.1 - 0.16 11.5 0.0 0.53 9.9 0.0 1.8 1 1 1 2 2 2 0 Nodulation protein S (NodS) DUF4602 PF15375.6 ORY15645.1 - 0.00071 19.9 41.0 0.12 12.7 39.8 3.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) Prefoldin PF02996.17 ORY15646.1 - 2.2e-25 88.9 0.2 2.9e-25 88.5 0.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit TPR_MLP1_2 PF07926.12 ORY15646.1 - 0.0055 16.8 1.5 0.19 11.8 0.4 2.0 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 ORY15646.1 - 0.011 16.0 0.9 0.031 14.5 0.1 2.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Mst1_SARAH PF11629.8 ORY15646.1 - 0.075 13.1 1.7 0.12 12.5 0.2 2.0 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 ZapB PF06005.12 ORY15646.1 - 0.079 13.4 1.8 0.079 13.4 1.8 2.0 2 0 0 2 2 2 0 Cell division protein ZapB RasGAP_C PF03836.15 ORY15646.1 - 0.093 12.9 2.6 0.33 11.1 0.9 2.0 2 0 0 2 2 2 0 RasGAP C-terminus GIT_CC PF16559.5 ORY15646.1 - 0.53 10.2 8.3 0.12 12.3 4.5 1.9 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 ORY15646.1 - 3 7.7 6.6 0.62 9.9 2.9 1.7 2 0 0 2 2 2 0 Septum formation initiator Glyco_hydro_47 PF01532.20 ORY15648.1 - 7.7e-113 377.8 0.0 1.2e-112 377.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 NolX PF05819.11 ORY15648.1 - 0.022 14.1 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 NolX protein LRR_4 PF12799.7 ORY15649.1 - 0.00042 20.6 0.8 5 7.7 0.0 3.7 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY15649.1 - 0.023 14.5 1.6 7.9 6.3 0.2 3.5 4 1 1 5 5 5 0 Leucine rich repeat LRR_8 PF13855.6 ORY15650.1 - 1.3e-13 50.4 15.5 4.1e-08 32.9 3.7 2.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY15650.1 - 2.3e-09 37.4 9.0 0.00028 21.2 0.4 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY15650.1 - 7.5e-07 28.8 3.9 2.5 9.0 0.3 4.2 4 0 0 4 4 4 3 Leucine Rich Repeat Dict-STAT-coil PF09267.10 ORY15650.1 - 0.0082 16.5 0.1 1.6 9.2 0.0 2.2 1 1 1 2 2 2 2 Dictyostelium STAT, coiled coil LRR_6 PF13516.6 ORY15650.1 - 0.01 15.8 9.3 5.1 7.4 0.9 4.0 4 0 0 4 4 4 0 Leucine Rich repeat LRR_9 PF14580.6 ORY15650.1 - 0.34 10.4 1.6 4.1 6.9 0.7 1.7 1 1 0 1 1 1 0 Leucine-rich repeat Pet127 PF08634.10 ORY15651.1 - 0.22 11.0 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial protein Pet127 LRR_4 PF12799.7 ORY15652.1 - 7.4e-05 23.0 4.2 0.33 11.4 0.3 3.4 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY15652.1 - 0.0066 16.2 0.9 0.0066 16.2 0.9 3.0 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 ORY15654.1 - 0.00055 19.8 0.1 0.014 15.4 0.0 3.1 3 0 0 3 3 3 1 Leucine Rich repeat Mg_trans_NIPA PF05653.14 ORY15655.1 - 2.4e-18 66.3 0.2 6.7e-18 64.8 0.1 1.7 1 1 1 2 2 2 1 Magnesium transporter NIPA LRR_8 PF13855.6 ORY15657.1 - 2.5e-13 49.6 11.6 1.7e-07 30.8 1.6 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY15657.1 - 5.1e-09 36.3 14.1 0.0039 17.6 1.3 3.5 2 2 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY15657.1 - 2e-06 27.5 16.3 0.093 13.3 0.2 5.6 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 ORY15657.1 - 7.6e-06 25.6 14.6 0.033 14.2 0.2 4.7 5 0 0 5 5 5 3 Leucine Rich repeat DUF3338 PF11819.8 ORY15657.1 - 0.019 15.0 0.3 2.6 8.0 0.0 2.7 1 1 1 3 3 3 0 Domain of unknown function (DUF3338) zf-MYND PF01753.18 ORY15658.1 - 4.9e-11 42.5 14.6 9.7e-11 41.6 14.6 1.5 1 1 0 1 1 1 1 MYND finger Cupin_5 PF06172.11 ORY15658.1 - 0.021 15.0 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily (DUF985) zf-C6H2 PF15801.5 ORY15658.1 - 0.064 13.6 6.6 0.064 13.6 6.6 1.9 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding RseC_MucC PF04246.12 ORY15658.1 - 0.076 13.0 0.2 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC zf-C2H2_4 PF13894.6 ORY15658.1 - 1.5 9.8 8.2 12 7.1 5.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Pkinase PF00069.25 ORY15659.1 - 2.6e-23 82.7 0.0 5.6e-23 81.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY15659.1 - 3.7e-13 49.4 0.0 6.6e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY15659.1 - 4.4e-09 35.6 0.2 4.4e-09 35.6 0.2 1.5 2 0 0 2 2 2 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 ORY15659.1 - 0.013 14.5 0.1 0.019 14.0 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.23 ORY15659.1 - 0.025 14.5 0.1 0.065 13.1 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family PurA PF04845.13 ORY15920.1 - 0.072 12.4 0.0 0.15 11.3 0.0 1.5 1 1 0 1 1 1 0 PurA ssDNA and RNA-binding protein DDE_3 PF13358.6 ORY16047.1 - 1.1e-19 70.7 0.0 1.3e-19 70.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Ribosomal_L21p PF00829.21 ORY16048.1 - 0.053 13.8 0.4 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 Ribosomal prokaryotic L21 protein ABC2_membrane_3 PF12698.7 ORY16202.1 - 0.0017 17.5 0.5 0.0019 17.4 0.5 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF1514 PF07438.11 ORY16202.1 - 0.043 13.7 0.5 0.16 11.9 0.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1514) RIFIN PF02009.16 ORY16202.1 - 0.067 13.1 2.8 0.086 12.7 2.8 1.1 1 0 0 1 1 1 0 Rifin TMIE PF16038.5 ORY16202.1 - 0.44 10.4 2.2 0.83 9.5 2.2 1.4 1 0 0 1 1 1 0 TMIE protein Stevor PF17410.2 ORY16202.1 - 2.9 7.4 9.4 4.3 6.8 9.4 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Peptidase_M14 PF00246.24 ORY16203.1 - 2.3e-60 204.9 1.2 2.9e-60 204.6 1.2 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase CTD_bind PF04818.13 ORY16203.1 - 0.057 14.2 0.0 0.12 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II-binding domain. Pam17 PF08566.10 ORY16325.1 - 7.4e-34 117.0 0.2 8.2e-34 116.8 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF2062 PF09835.9 ORY16325.1 - 0.032 14.1 0.2 0.044 13.7 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Y_phosphatase PF00102.27 ORY16326.1 - 1.1e-06 28.4 0.0 1.8e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 ORY16326.1 - 9.2e-06 25.8 0.0 1.5e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 ORY16326.1 - 1.2e-05 25.1 0.0 2.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 ORY16326.1 - 0.0015 18.7 0.0 0.0024 18.0 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate PTEN_C2 PF10409.9 ORY16326.1 - 0.033 13.9 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Pam17 PF08566.10 ORY16327.1 - 1.1e-24 87.1 0.4 1.4e-24 86.8 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 zf-C3HC4_2 PF13923.6 ORY16513.1 - 9.5e-12 44.6 5.9 9.5e-12 44.6 5.9 4.4 3 2 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY16513.1 - 4.8e-10 39.1 3.8 4.8e-10 39.1 3.8 4.6 2 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY16513.1 - 2.9e-09 36.8 6.3 2.9e-09 36.8 6.3 3.7 3 1 0 3 3 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 ORY16513.1 - 7.8e-09 35.7 5.5 7.8e-09 35.7 5.5 4.0 3 1 1 4 4 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORY16513.1 - 2.5e-07 30.5 2.7 2.5e-07 30.5 2.7 4.2 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY16513.1 - 8.7e-07 29.0 4.8 8.7e-07 29.0 4.8 4.0 3 2 0 3 3 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 ORY16513.1 - 2.4e-05 24.4 2.7 2.4e-05 24.4 2.7 3.3 3 1 0 3 3 3 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 ORY16513.1 - 3.7e-05 23.5 3.4 3.7e-05 23.5 3.4 3.7 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 ORY16513.1 - 0.0001 22.1 2.0 0.0001 22.1 2.0 2.8 2 1 1 3 3 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 ORY16513.1 - 0.00014 22.0 4.0 0.00014 22.0 4.0 3.4 2 2 1 3 3 1 1 RING-H2 zinc finger domain U-box PF04564.15 ORY16513.1 - 0.00015 21.8 0.1 0.00038 20.6 0.1 1.6 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 ORY16513.1 - 0.00022 21.0 2.2 0.00022 21.0 2.2 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 ORY16513.1 - 0.027 14.2 3.9 0.027 14.2 3.9 3.3 4 0 0 4 4 4 0 RING-like zinc finger E1-E2_ATPase PF00122.20 ORY16515.1 - 6.6e-49 165.9 0.3 6.6e-49 165.9 0.3 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY16515.1 - 2e-20 73.3 15.4 4.3e-16 59.2 5.0 3.2 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY16515.1 - 6.1e-18 65.9 0.6 8.8e-10 39.2 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY16515.1 - 1.9e-17 63.1 0.0 4e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORY16515.1 - 1.1e-12 47.4 0.0 3e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY16515.1 - 0.0032 17.2 1.1 0.2 11.4 0.6 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FIST PF08495.10 ORY16515.1 - 0.15 12.0 0.2 0.47 10.5 0.2 1.8 1 0 0 1 1 1 0 FIST N domain Strabismus PF06638.11 ORY16515.1 - 0.65 8.6 2.4 1.1 7.8 2.4 1.3 1 0 0 1 1 1 0 Strabismus protein Baculo_PEP_C PF04513.12 ORY17043.1 - 6.2 6.9 11.4 1.3 9.1 6.8 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Helicase_C PF00271.31 ORY17045.1 - 1.6e-12 47.7 0.0 3.2e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 ORY17045.1 - 0.0087 16.8 0.1 0.02 15.6 0.1 1.6 1 0 0 1 1 1 1 RecQ zinc-binding NPH3 PF03000.14 ORY17046.1 - 0.094 12.3 1.5 1.4 8.5 0.3 2.7 2 0 0 2 2 2 0 NPH3 family Peptidase_S8 PF00082.22 ORY17356.1 - 8.7e-47 159.8 4.8 1.3e-46 159.3 4.8 1.2 1 0 0 1 1 1 1 Subtilase family PA PF02225.22 ORY17356.1 - 6.8e-07 29.2 0.5 2.2e-06 27.6 0.5 1.9 1 0 0 1 1 1 1 PA domain fn3_5 PF06280.12 ORY17356.1 - 0.00093 19.9 0.2 0.0031 18.2 0.2 1.9 1 1 0 1 1 1 1 Fn3-like domain NPCBM_assoc PF10633.9 ORY17356.1 - 0.033 14.4 0.1 0.13 12.5 0.1 2.0 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Utp11 PF03998.13 ORY17357.1 - 1.9e-67 227.8 34.0 2.2e-67 227.6 34.0 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 ORY17357.1 - 0.15 11.4 1.9 0.18 11.1 0.5 1.7 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF2250 PF10007.9 ORY17357.1 - 8.6 6.6 12.3 0.68 10.1 2.4 3.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2250) IQ PF00612.27 ORY17358.1 - 5.5e-09 35.0 15.1 0.0033 17.1 0.3 3.8 4 0 0 4 4 4 3 IQ calmodulin-binding motif HOOK PF05622.12 ORY17359.1 - 0.037 12.2 36.9 0.11 10.7 12.9 3.1 2 1 1 3 3 3 0 HOOK protein Mur_ligase PF01225.25 ORY17359.1 - 0.095 13.0 0.0 0.29 11.5 0.0 1.7 1 0 0 1 1 1 0 Mur ligase family, catalytic domain KASH_CCD PF14662.6 ORY17359.1 - 0.72 9.7 41.2 0.37 10.6 19.2 3.7 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 ORY17359.1 - 1.6 7.5 40.3 0.82 8.5 3.4 3.3 2 1 1 3 3 3 0 Spc7 kinetochore protein ZnuA PF01297.17 ORY17359.1 - 9.7 5.5 10.1 9.4 5.6 5.2 2.3 2 1 0 2 2 2 0 Zinc-uptake complex component A periplasmic ERG4_ERG24 PF01222.17 ORY17360.1 - 1.5e-96 323.8 19.0 1.7e-96 323.7 19.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 ORY17360.1 - 0.0011 18.6 0.1 0.0026 17.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 ORY17360.1 - 0.072 13.5 0.1 0.21 12.1 0.1 1.8 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family RseC_MucC PF04246.12 ORY17361.1 - 0.096 12.6 0.3 0.71 9.8 0.1 2.1 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Ribosomal_S3_C PF00189.20 ORY17362.1 - 0.004 17.6 0.0 0.0059 17.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain Cellulase PF00150.18 ORY17364.1 - 0.0023 17.4 0.1 0.0087 15.5 0.1 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Rax2 PF12768.7 ORY17365.1 - 0.13 11.7 0.1 3.8 6.9 0.0 2.2 2 0 0 2 2 2 0 Cortical protein marker for cell polarity OrsD PF12013.8 ORY17716.1 - 0.85 10.1 7.6 0.18 12.2 2.3 2.5 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D RabGAP-TBC PF00566.18 ORY17717.1 - 3.2e-28 98.9 0.0 5.7e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 ORY17717.1 - 1.8e-18 66.9 0.0 2.7e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY17717.1 - 4.3e-14 52.4 0.0 6.9e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Rhodanese PF00581.20 ORY17717.1 - 0.012 16.1 0.0 0.04 14.5 0.0 1.8 2 0 0 2 2 2 0 Rhodanese-like domain Nucleotid_trans PF03407.16 ORY17718.1 - 1.2e-11 45.0 0.1 2.8e-11 43.8 0.1 1.7 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase TauD PF02668.16 ORY17719.1 - 9.5e-46 156.7 0.1 1.2e-45 156.4 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Nucleotid_trans PF03407.16 ORY17721.1 - 1.4e-05 25.2 0.0 1.4e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF2299 PF10061.9 ORY17721.1 - 0.019 14.7 0.0 0.02 14.6 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2299) WD40 PF00400.32 ORY17722.1 - 2.1e-16 60.0 19.8 0.0033 18.2 0.0 6.1 5 1 0 5 5 5 5 WD domain, G-beta repeat DDE_Tnp_4 PF13359.6 ORY17876.1 - 7.7e-19 67.9 0.0 9.4e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 ORY17876.1 - 0.001 18.8 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DAN PF03045.15 ORY17876.1 - 0.2 11.7 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 DAN domain DUF1729 PF08354.10 ORY17900.1 - 2.4e-27 95.8 0.1 3e-14 52.7 0.0 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF1729) WW PF00397.26 ORY17902.1 - 3.8e-14 52.5 0.1 5.3e-08 32.8 0.0 2.6 2 0 0 2 2 2 2 WW domain HECT PF00632.25 ORY17902.1 - 1.5e-07 31.2 0.2 2.4e-07 30.6 0.2 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ColG_sub PF18496.1 ORY17903.1 - 0.00054 20.1 1.9 52 4.0 0.1 7.5 1 1 12 13 13 13 1 Collagenase G catalytic helper subdomain Chorion_S16 PF05836.12 ORY17904.1 - 0.038 14.2 0.0 0.044 14.0 0.0 1.2 1 0 0 1 1 1 0 Chorion protein S16 FATC PF02260.20 ORY18076.1 - 0.037 13.8 0.8 0.17 11.7 0.0 2.5 3 0 0 3 3 3 0 FATC domain DASH_Spc19 PF08287.11 ORY18076.1 - 0.69 9.8 6.5 2.3 8.1 6.5 1.8 2 0 0 2 2 2 0 Spc19 UL42 PF17638.2 ORY18076.1 - 1 9.4 4.9 1 9.4 2.7 2.1 2 0 0 2 2 2 0 HCMV UL42 ABC_tran PF00005.27 ORY18078.1 - 2.5e-25 89.6 0.0 5.5e-25 88.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 ORY18078.1 - 3.8e-11 42.8 5.6 3.8e-11 42.8 5.6 2.6 2 1 1 3 3 3 1 ABC-2 type transporter T2SSE PF00437.20 ORY18078.1 - 0.00057 19.0 0.1 0.00099 18.2 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Rad17 PF03215.15 ORY18078.1 - 0.0021 18.0 0.2 0.0042 17.0 0.2 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_25 PF13481.6 ORY18078.1 - 0.0027 17.3 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ORY18078.1 - 0.014 15.3 0.1 0.028 14.3 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 ORY18078.1 - 0.02 15.3 0.0 0.047 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 ORY18078.1 - 0.022 15.2 0.0 0.04 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 ORY18078.1 - 0.031 14.0 0.1 0.092 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 ORY18078.1 - 0.034 13.6 0.1 0.16 11.4 0.1 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORY18078.1 - 0.041 14.4 0.3 0.041 14.4 0.3 1.7 2 0 0 2 2 1 0 AAA domain ATPase_2 PF01637.18 ORY18078.1 - 0.042 13.8 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 ORY18078.1 - 0.051 13.8 0.1 0.15 12.3 0.1 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ORY18078.1 - 0.092 12.7 0.2 0.17 11.8 0.2 1.4 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 ORY18078.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ORY18078.1 - 0.12 12.2 0.3 0.31 10.8 0.2 1.7 1 1 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 ORY18078.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 KaiC LapA_dom PF06305.11 ORY18078.1 - 0.29 11.0 3.9 11 5.9 0.3 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain AAA_11 PF13086.6 ORY18078.1 - 0.52 10.0 0.0 0.52 10.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain z-alpha PF02295.17 ORY18894.1 - 0.092 12.8 0.4 0.2 11.7 0.4 1.6 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain DUF3802 PF12290.8 ORY18894.1 - 0.093 13.2 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3802) DUF349 PF03993.12 ORY18894.1 - 0.49 10.7 7.1 7.5 6.9 0.1 2.6 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) DNA_pol_A_exo1 PF01612.20 ORY18897.1 - 7.6e-11 42.0 0.0 4.4e-10 39.5 0.0 2.2 2 1 1 3 3 3 1 3'-5' exonuclease 5_3_exonuc_N PF02739.16 ORY18897.1 - 0.049 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain DDE_Tnp_4 PF13359.6 ORY18898.1 - 5.6e-08 32.6 0.0 6.3e-08 32.4 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease RRM_1 PF00076.22 ORY19082.1 - 2.2e-14 53.0 0.0 1.6e-12 47.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_B PF00136.21 ORY19083.1 - 8e-37 127.0 0.2 2e-36 125.7 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B zf-C4pol PF14260.6 ORY19083.1 - 1.7e-12 47.6 2.6 3e-12 46.8 2.6 1.4 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta TEX12 PF15219.6 ORY19083.1 - 0.038 14.3 0.5 0.13 12.6 0.0 2.1 3 0 0 3 3 3 0 Testis-expressed 12 NinF PF05810.12 ORY19083.1 - 0.059 13.2 0.5 0.12 12.3 0.5 1.5 1 0 0 1 1 1 0 NinF protein zf-ACC PF17848.1 ORY19083.1 - 0.23 11.6 0.2 0.23 11.6 0.2 2.2 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain DZR PF12773.7 ORY19083.1 - 3.3 7.8 6.9 18 5.5 6.9 2.0 1 1 0 1 1 1 0 Double zinc ribbon RRM_1 PF00076.22 ORY19084.1 - 4e-14 52.2 0.1 3.2e-12 46.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPX2_importin PF12214.8 ORY19084.1 - 0.067 13.4 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Cell cycle regulated microtubule associated protein Asp_protease_2 PF13650.6 ORY19114.1 - 0.032 14.9 0.0 0.092 13.4 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease Pkinase PF00069.25 ORY19351.1 - 5.2e-65 219.4 0.0 6.5e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY19351.1 - 7.7e-38 130.2 0.0 9.7e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY19351.1 - 8.9e-08 31.8 0.0 1.5e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY19351.1 - 0.00014 20.7 0.0 0.00022 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY19351.1 - 0.00041 19.4 0.5 0.00056 19.0 0.5 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY19351.1 - 0.00044 19.7 0.2 0.00086 18.7 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY19351.1 - 0.00054 20.0 0.3 0.00084 19.3 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 ORY19351.1 - 0.0082 15.8 0.3 0.21 11.2 0.2 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 ORY19352.1 - 6.2e-62 209.3 0.1 9.6e-62 208.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY19352.1 - 6.2e-33 114.2 0.0 9e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY19352.1 - 1.2e-09 37.9 0.0 1.9e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY19352.1 - 0.00067 19.1 0.0 0.0013 18.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY19352.1 - 0.0082 15.1 0.2 0.015 14.3 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY19352.1 - 0.023 14.6 0.0 0.055 13.4 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 ORY19352.1 - 0.035 13.7 0.4 1.7 8.2 0.1 2.5 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 ORY19352.1 - 0.052 12.3 2.3 0.23 10.2 0.0 2.5 2 1 1 3 3 3 0 Fungal protein kinase Pkinase PF00069.25 ORY19353.1 - 2.6e-56 190.9 0.0 3.5e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY19353.1 - 1.2e-34 119.8 0.0 1.5e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY19353.1 - 1.4e-12 47.6 0.0 2.1e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY19353.1 - 0.0001 21.7 0.1 0.00015 21.2 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY19353.1 - 0.0013 17.8 0.6 0.0019 17.2 0.6 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY19353.1 - 0.0022 17.9 0.0 0.0032 17.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY19353.1 - 0.11 11.3 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase UvrD_C PF13361.6 ORY19370.1 - 3.1e-10 39.9 0.0 2.5e-06 27.1 0.0 2.6 1 1 1 2 2 2 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 ORY19370.1 - 1e-07 31.8 4.4 0.00011 21.8 0.1 3.4 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 ORY19370.1 - 2.4e-07 31.2 0.1 0.00031 21.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.6 ORY19370.1 - 4.2e-07 29.7 0.0 0.028 14.2 0.0 2.6 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 ORY19370.1 - 0.00066 19.5 0.9 1.2 8.8 0.0 4.4 4 1 0 4 4 4 1 Viral (Superfamily 1) RNA helicase AAA_12 PF13087.6 ORY19370.1 - 0.075 12.6 0.0 1.8 8.1 0.0 2.6 1 1 0 2 2 2 0 AAA domain F-box-like PF12937.7 ORY19628.1 - 1.6e-07 31.1 2.0 1.7e-07 31.0 0.8 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY19628.1 - 5.9e-05 22.8 1.8 0.00012 21.8 1.4 1.7 1 1 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ORY19628.1 - 0.014 15.3 0.4 0.046 13.6 0.0 2.0 2 1 0 2 2 2 0 F-box ArfGap PF01412.18 ORY19911.1 - 1.8e-28 98.9 0.4 2.2e-28 98.7 0.4 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-dskA_traR PF01258.17 ORY19911.1 - 0.096 12.6 2.1 5.4 7.0 0.1 2.4 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Snapin_Pallidin PF14712.6 ORY19914.1 - 0.019 15.3 0.2 0.06 13.8 0.2 1.8 1 0 0 1 1 1 0 Snapin/Pallidin P53_tetramer PF07710.11 ORY19914.1 - 0.027 13.8 0.1 0.06 12.7 0.1 1.6 1 0 0 1 1 1 0 P53 tetramerisation motif PIF1 PF05970.14 ORY19915.1 - 1.1e-07 31.4 0.3 1.1e-07 31.3 0.3 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 ORY19915.1 - 0.0017 18.1 0.5 0.0042 16.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY19915.1 - 0.012 16.0 0.8 0.12 12.7 0.8 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY19915.1 - 0.043 14.2 0.0 0.046 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ORY19915.1 - 0.075 13.3 0.0 0.08 13.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain DUF3112 PF11309.8 ORY19916.1 - 0.021 14.3 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) Pollen_allerg_2 PF01620.16 ORY19917.1 - 0.032 14.5 0.0 0.31 11.2 0.0 2.0 2 0 0 2 2 2 0 Ribonuclease (pollen allergen) Gti1_Pac2 PF09729.9 ORY19919.1 - 6.7e-12 45.9 2.6 0.00016 21.8 0.0 3.4 2 1 2 4 4 4 3 Gti1/Pac2 family zf-CCHC PF00098.23 ORY19922.1 - 8.4e-07 28.8 1.9 1.6e-06 27.9 1.9 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF1510 PF07423.11 ORY19922.1 - 0.011 15.9 0.7 0.024 14.8 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1510) zf-CCHH PF10283.9 ORY19923.1 - 0.16 12.0 0.3 8.2 6.5 0.5 2.6 2 0 0 2 2 2 0 PBZ domain DUF3720 PF12517.8 ORY19924.1 - 0.21 12.5 7.9 0.081 13.9 3.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3720) Rep_fac_C PF08542.11 ORY19925.1 - 5.1e-07 30.0 0.0 1.4e-06 28.6 0.0 1.7 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 ORY19925.1 - 0.0014 18.4 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 ORY19925.1 - 0.027 14.9 0.0 0.043 14.2 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FTR1 PF03239.14 ORY19956.1 - 8.5e-58 195.9 3.2 1.4e-35 123.0 0.3 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family DUF3180 PF11377.8 ORY19956.1 - 0.17 12.0 13.4 0.18 11.9 3.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3180) Cytochrom_B561 PF03188.16 ORY19956.1 - 1.9 8.6 11.3 0.049 13.8 2.7 2.6 3 0 0 3 3 3 0 Eukaryotic cytochrome b561 Carboxyl_trans PF01039.22 ORY19980.1 - 1.4e-131 439.5 0.0 4.9e-79 266.3 0.0 2.0 1 1 1 2 2 2 2 Carboxyl transferase domain MdcE PF06833.11 ORY19980.1 - 0.049 13.1 0.2 0.18 11.2 0.0 1.9 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) TauD PF02668.16 ORY19981.1 - 7.2e-37 127.6 3.7 4.6e-29 102.0 0.1 2.1 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family T4SS_TraI PF16932.5 ORY19981.1 - 0.052 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Type IV secretory system, conjugal DNA-protein transfer SIR2 PF02146.17 ORY19983.1 - 5.4e-23 81.8 0.7 7.8e-15 55.2 0.1 2.0 1 1 1 2 2 2 2 Sir2 family zf-HC3 PF16827.5 ORY19983.1 - 2 8.7 7.7 0.32 11.2 1.6 2.6 2 1 0 2 2 2 0 zinc-finger zf-FPG_IleRS PF06827.14 ORY19985.1 - 0.041 13.7 1.5 0.15 11.9 0.1 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Glyco_transf_43 PF03360.16 ORY19986.1 - 0.00071 19.5 0.0 0.00091 19.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 43 FKBP_C PF00254.28 ORY19987.1 - 1.4e-21 76.6 0.0 1.9e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Med9 PF07544.13 ORY19990.1 - 0.18 11.9 2.8 0.42 10.7 1.4 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 FSH1 PF03959.13 ORY19992.1 - 1.2e-17 64.3 0.0 7.4e-08 32.3 0.0 2.0 1 1 1 2 2 2 2 Serine hydrolase (FSH1) DUF3868 PF12984.7 ORY19992.1 - 0.00033 20.4 0.0 0.00068 19.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function, B. Theta Gene description (DUF3868) FSH1 PF03959.13 ORY19993.1 - 2.6e-42 144.9 0.0 3.1e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 ORY19993.1 - 0.014 15.2 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase AIP3 PF03915.13 ORY19993.1 - 0.24 10.4 0.0 0.3 10.1 0.0 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 PGAP1 PF07819.13 ORY19994.1 - 2.7e-06 27.3 0.0 5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 ORY19994.1 - 1.2e-05 25.2 0.0 1.7e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 ORY19994.1 - 2.4e-05 24.0 0.0 4.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 ORY19994.1 - 7.7e-05 22.5 0.0 0.00039 20.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.15 ORY19994.1 - 0.00052 19.3 0.0 0.00072 18.8 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 ORY19994.1 - 0.0029 18.2 0.0 0.005 17.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 ORY19994.1 - 0.0033 16.8 0.0 0.0073 15.7 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) PriCT_1 PF08708.11 ORY19994.1 - 0.043 13.5 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Primase C terminal 1 (PriCT-1) DUF900 PF05990.12 ORY19994.1 - 0.068 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PAF-AH_p_II PF03403.13 ORY19995.1 - 9.8e-09 34.2 0.1 1.2e-08 33.9 0.1 1.0 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydro_lipase PF04083.16 ORY19995.1 - 0.061 12.9 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region PAF-AH_p_II PF03403.13 ORY19996.1 - 3.1e-55 187.2 0.0 7.5e-55 186.0 0.0 1.5 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 ORY19996.1 - 7.2e-13 48.0 0.0 1.9e-12 46.6 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 ORY19996.1 - 2.1e-08 33.9 0.1 3.3e-07 30.0 0.0 2.6 2 1 1 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ORY19996.1 - 1e-07 31.5 0.0 0.0094 15.2 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 ORY19996.1 - 5.3e-07 29.0 0.0 0.00065 18.8 0.0 2.7 3 0 0 3 3 3 2 Chlorophyllase Abhydrolase_1 PF00561.20 ORY19996.1 - 1e-06 28.6 0.4 1.8e-05 24.5 0.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY19996.1 - 0.0014 19.3 0.0 0.0017 19.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 ORY19996.1 - 0.002 17.8 0.0 0.018 14.7 0.0 2.0 2 0 0 2 2 2 1 Putative esterase Abhydrolase_5 PF12695.7 ORY19996.1 - 0.0043 16.8 0.0 0.3 10.8 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 ORY19996.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.4 1 1 0 1 1 1 0 Dienelactone hydrolase family PAF-AH_p_II PF03403.13 ORY19997.1 - 1e-24 86.8 0.0 1.2e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 ORY19997.1 - 3.6e-05 22.8 0.0 4.7e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 ORY19997.1 - 0.00012 21.3 0.0 0.00014 21.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 ORY19997.1 - 0.00067 19.0 0.0 0.00081 18.7 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 HGTP_anticodon PF03129.20 ORY19999.1 - 2.9e-16 59.4 0.0 6.8e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 ORY19999.1 - 5.8e-08 32.9 0.1 1.4e-07 31.6 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_1 PF00133.22 ORY20000.1 - 1.1e-34 119.7 0.0 1.5e-19 69.7 0.0 4.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 ORY20000.1 - 2.1e-17 63.0 0.0 5e-09 35.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 ORY20000.1 - 8.3e-10 38.8 0.0 2.4e-09 37.3 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 ORY20000.1 - 2.3e-07 30.5 0.0 6e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF1367 PF07105.11 ORY20000.1 - 0.022 14.4 0.0 0.059 13.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1367) CNOT11 PF10155.9 ORY20001.1 - 5.9e-36 123.4 1.8 9.5e-36 122.7 0.4 1.9 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 11 Methyltransf_15 PF09445.10 ORY20002.1 - 1.9e-44 151.1 0.0 2.6e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 ORY20002.1 - 5.9e-07 30.1 0.0 1.1e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY20002.1 - 2.6e-06 27.3 0.0 4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 ORY20002.1 - 1.3e-05 25.0 0.1 0.00013 21.8 0.1 2.0 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 ORY20002.1 - 3e-05 23.7 0.0 4.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 ORY20002.1 - 6.9e-05 22.7 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 ORY20002.1 - 0.00055 19.4 0.1 0.00085 18.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ORY20002.1 - 0.0014 18.2 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.12 ORY20002.1 - 0.0023 18.6 0.0 0.0047 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY20002.1 - 0.0052 16.2 0.0 0.009 15.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.14 ORY20002.1 - 0.0096 15.3 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MethyltransfD12 PF02086.15 ORY20002.1 - 0.051 13.3 0.1 0.45 10.1 0.1 2.1 1 1 1 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_23 PF13489.6 ORY20002.1 - 0.076 12.8 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_5 PF01795.19 ORY20002.1 - 0.18 11.3 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 MraW methylase family HalX PF08663.10 ORY20004.1 - 3.6 8.0 7.3 3.8 7.9 3.8 2.1 2 0 0 2 2 2 0 HalX domain DUF5344 PF17279.2 ORY20041.1 - 0.0012 19.4 0.2 0.008 16.7 0.2 2.3 2 0 0 2 2 2 1 Family of unknown function (DUF5344) Ribosom_S12_S23 PF00164.25 ORY20042.1 - 0.079 12.6 0.2 0.12 12.0 0.1 1.5 1 1 1 2 2 2 0 Ribosomal protein S12/S23 DUF4587 PF15248.6 ORY20046.1 - 0.28 12.0 0.4 0.28 12.0 0.4 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4587) Glyoxalase PF00903.25 ORY20047.1 - 0.0003 21.0 0.1 0.0008 19.6 0.1 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 ORY20047.1 - 0.024 14.6 0.0 0.06 13.3 0.0 1.6 1 1 0 1 1 1 0 Glyoxalase-like domain DUF604 PF04646.12 ORY20047.1 - 0.053 12.9 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF604 DUF3914 PF13053.6 ORY20076.1 - 0.0042 17.4 1.5 0.028 14.7 1.5 2.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3914) Sec20 PF03908.13 ORY20076.1 - 0.0046 16.8 0.1 0.0046 16.8 0.1 4.0 4 1 1 5 5 5 1 Sec20 PdxJ PF03740.13 ORY20076.1 - 0.0059 15.8 0.2 0.017 14.2 0.2 1.8 1 0 0 1 1 1 1 Pyridoxal phosphate biosynthesis protein PdxJ DUF98 PF01947.16 ORY20076.1 - 0.01 15.8 0.2 7.6 6.5 0.5 3.0 1 1 1 2 2 2 0 p-hydroxybenzoic acid synthase zinc_ribbon_9 PF14369.6 ORY20076.1 - 0.34 11.2 4.5 3.2 8.1 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon L27_N PF09060.10 ORY20076.1 - 1.3 9.1 5.3 12 6.0 0.4 3.5 3 0 0 3 3 3 0 L27_N Lipase_3 PF01764.25 ORY20104.1 - 1.8e-12 47.3 0.1 6.6e-12 45.5 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) HAUS6_N PF14661.6 ORY20104.1 - 0.016 14.8 0.4 0.03 13.9 0.4 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus ALIX_LYPXL_bnd PF13949.6 ORY20104.1 - 0.11 11.7 2.5 0.095 12.0 0.7 1.7 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV DUF1043 PF06295.12 ORY20104.1 - 0.27 11.3 2.2 0.35 10.9 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) CsgE PF10627.9 ORY20122.1 - 0.12 12.7 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Curli assembly protein CsgE GST_N_3 PF13417.6 ORY20143.1 - 1.3e-07 31.9 0.0 3.5e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY20143.1 - 6e-07 29.7 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain BCSC_C PF05420.11 ORY20143.1 - 0.18 10.9 0.0 0.25 10.4 0.0 1.1 1 0 0 1 1 1 0 Cellulose synthase operon protein C C-terminus (BCSC_C) NifW PF03206.14 ORY20167.1 - 0.013 16.0 0.5 0.021 15.4 0.5 1.3 1 0 0 1 1 1 0 Nitrogen fixation protein NifW RIG-I_C PF18119.1 ORY20167.1 - 0.022 14.8 0.2 0.11 12.5 0.0 1.9 1 1 1 2 2 2 0 RIG-I receptor C-terminal domain Stress-antifung PF01657.17 ORY20167.1 - 0.11 13.2 0.1 0.22 12.2 0.0 1.6 2 0 0 2 2 2 0 Salt stress response/antifungal Plavaka PF18759.1 ORY20168.1 - 4.2e-25 88.7 0.0 4.9e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase SDA1 PF05285.12 ORY20169.1 - 0.0037 16.7 9.4 0.0054 16.2 9.4 1.3 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 ORY20169.1 - 0.005 15.1 14.7 0.0071 14.6 14.7 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.14 ORY20169.1 - 0.0068 14.8 5.9 0.025 12.9 6.5 1.7 2 0 0 2 2 2 1 CDC45-like protein BUD22 PF09073.10 ORY20169.1 - 0.22 10.8 11.9 0.37 10.1 11.9 1.3 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 ORY20169.1 - 0.37 8.9 21.7 0.59 8.2 21.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi TRAP_alpha PF03896.16 ORY20169.1 - 0.45 9.7 5.4 0.71 9.0 5.4 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit BSP_II PF05432.11 ORY20169.1 - 1 9.0 21.8 1.9 8.1 21.8 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) COPI_C PF06957.11 ORY20169.1 - 2.5 6.7 9.1 4 6.1 9.1 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus PTPRCAP PF15713.5 ORY20169.1 - 2.9 8.2 14.6 5.6 7.2 14.6 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated SspB PF04386.13 ORY20169.1 - 4 7.3 7.3 7.9 6.3 7.3 1.4 1 0 0 1 1 1 0 Stringent starvation protein B DUF2722 PF10846.8 ORY20169.1 - 4.6 6.1 11.2 6.8 5.5 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2457 PF10446.9 ORY20169.1 - 7.7 5.5 22.2 13 4.8 22.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pox_Ag35 PF03286.14 ORY20169.1 - 8.4 6.1 12.2 20 4.9 12.2 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CobT PF06213.12 ORY20169.1 - 8.6 5.7 15.8 15 4.8 15.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT zf_C2H2_ZHX PF18387.1 ORY20301.1 - 0.029 14.0 5.8 1.2 8.8 0.8 2.5 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain OrsD PF12013.8 ORY20301.1 - 0.16 12.4 6.5 0.44 11.0 1.5 2.8 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2 PF00096.26 ORY20301.1 - 2.1 9.0 11.0 2.5 8.7 0.1 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type Colicin-DNase PF12639.7 ORY20302.1 - 0.59 11.0 7.4 17 6.3 2.2 2.7 1 1 1 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin WHH PF14414.6 ORY20302.1 - 0.97 9.3 12.2 5.3 7.0 0.5 3.2 2 1 1 3 3 3 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH DUF3450 PF11932.8 ORY20303.1 - 0.00077 18.8 1.2 0.001 18.4 1.0 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) Nsp1_C PF05064.13 ORY20303.1 - 0.00095 19.0 1.0 0.0011 18.8 1.0 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region ZapB PF06005.12 ORY20303.1 - 0.0011 19.4 4.4 0.0014 19.0 4.4 1.3 1 1 0 1 1 1 1 Cell division protein ZapB BLOC1_2 PF10046.9 ORY20303.1 - 0.0022 18.2 0.8 0.0029 17.9 0.8 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 ORY20303.1 - 0.0029 17.5 0.9 0.0033 17.3 0.9 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 BST2 PF16716.5 ORY20303.1 - 0.0042 17.6 2.2 0.0053 17.3 2.2 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 GAS PF13851.6 ORY20303.1 - 0.0057 16.0 2.8 0.0064 15.9 2.8 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding YabA PF06156.13 ORY20303.1 - 0.018 15.6 1.2 0.022 15.4 1.2 1.2 1 0 0 1 1 1 0 Initiation control protein YabA CCDC92 PF14916.6 ORY20303.1 - 0.019 14.7 3.5 0.034 13.9 3.3 1.6 1 1 0 1 1 1 0 Coiled-coil domain of unknown function Cluap1 PF10234.9 ORY20303.1 - 0.019 14.4 1.4 0.02 14.3 1.4 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Herpes_UL6 PF01763.16 ORY20303.1 - 0.019 13.5 1.5 0.02 13.5 1.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like HlyD_D23 PF16576.5 ORY20303.1 - 0.027 13.7 1.0 0.029 13.6 1.0 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion TMF_DNA_bd PF12329.8 ORY20303.1 - 0.034 14.1 1.1 0.034 14.1 1.1 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Rab_bind PF16704.5 ORY20303.1 - 0.034 14.2 0.3 2.8 8.1 0.1 2.3 1 1 1 2 2 2 0 Rab binding domain Sec34 PF04136.15 ORY20303.1 - 0.035 14.0 1.3 0.039 13.8 1.3 1.1 1 0 0 1 1 1 0 Sec34-like family APG6_N PF17675.1 ORY20303.1 - 0.046 14.3 2.7 0.062 13.8 2.7 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF948 PF06103.11 ORY20303.1 - 0.077 13.3 0.4 0.11 12.8 0.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 ORY20303.1 - 0.13 12.5 2.9 0.52 10.5 2.8 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 ORY20303.1 - 0.14 12.4 1.7 0.27 11.5 1.7 1.5 1 0 0 1 1 1 0 Haemolysin XhlA USP8_interact PF08941.10 ORY20303.1 - 0.15 11.9 1.9 0.18 11.6 1.9 1.1 1 0 0 1 1 1 0 USP8 interacting SlyX PF04102.12 ORY20303.1 - 0.27 11.9 4.6 2.1 9.0 4.6 2.1 1 1 0 1 1 1 0 SlyX DivIC PF04977.15 ORY20303.1 - 0.77 9.6 4.7 3.7 7.4 4.7 2.0 1 1 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 ORY20303.1 - 0.98 9.6 3.9 3.9 7.6 1.2 2.3 1 1 1 2 2 2 0 Basic region leucine zipper ASFV_J13L PF05568.11 ORY20304.1 - 0.055 13.2 4.8 0.077 12.7 0.5 2.3 2 0 0 2 2 2 0 African swine fever virus J13L protein GST_N PF02798.20 ORY20305.1 - 4.1e-14 52.7 0.0 1e-13 51.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY20305.1 - 9.3e-11 41.9 0.0 3.8e-10 39.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY20305.1 - 6e-10 39.4 0.0 1.1e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY20305.1 - 9.3e-09 35.4 0.0 1.3e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY20305.1 - 1.2e-08 34.8 0.2 2.6e-08 33.7 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY20305.1 - 0.003 17.7 0.0 0.0047 17.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 ORY20305.1 - 0.05 14.3 0.0 0.13 13.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain bZIP_1 PF00170.21 ORY20333.1 - 0.0016 18.5 5.4 0.003 17.6 5.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF16 PF01519.16 ORY20333.1 - 0.048 14.1 0.7 0.091 13.3 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 ORY20333.1 - 0.11 13.0 2.1 0.37 11.3 0.4 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 ORY20333.1 - 0.74 9.6 4.3 1.4 8.7 4.3 1.5 1 0 0 1 1 1 0 Septum formation initiator Adaptin_binding PF10199.9 ORY20333.1 - 1.8 9.2 5.4 3.5 8.2 5.4 1.4 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 RsgA_GTPase PF03193.16 ORY20334.1 - 0.00039 20.3 0.1 0.0011 18.9 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 ORY20334.1 - 0.008 16.3 0.0 0.02 15.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY20334.1 - 0.01 15.6 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 ORY20334.1 - 0.029 14.9 0.3 0.26 11.8 0.0 2.4 2 1 1 3 3 3 0 ABC transporter LXG PF04740.12 ORY20335.1 - 0.002 17.9 3.7 0.002 17.9 3.7 2.9 2 1 0 2 2 2 1 LXG domain of WXG superfamily EzrA PF06160.12 ORY20335.1 - 0.0026 16.0 15.4 0.091 10.9 2.0 2.6 2 1 0 2 2 2 2 Septation ring formation regulator, EzrA TACC_C PF05010.14 ORY20335.1 - 0.004 17.0 1.4 0.004 17.0 1.4 2.5 2 0 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Spc7 PF08317.11 ORY20335.1 - 0.0097 14.8 1.0 0.0097 14.8 1.0 2.4 2 0 0 2 2 2 1 Spc7 kinetochore protein ApoO PF09769.9 ORY20335.1 - 0.028 14.4 0.2 4.5 7.2 0.0 3.0 2 1 1 3 3 3 0 Apolipoprotein O Laminin_II PF06009.12 ORY20335.1 - 0.029 14.4 0.2 0.029 14.4 0.2 3.7 3 1 1 4 4 3 0 Laminin Domain II DUF2524 PF10732.9 ORY20335.1 - 0.042 14.1 0.8 0.042 14.1 0.8 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2524) CHDCT2 PF08074.11 ORY20335.1 - 0.12 12.5 7.9 0.48 10.6 2.2 2.6 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain STAT_alpha PF01017.20 ORY20335.1 - 0.22 11.4 8.0 0.21 11.5 1.2 2.6 2 0 0 2 2 2 0 STAT protein, all-alpha domain DUF1845 PF08900.11 ORY20335.1 - 0.61 9.8 3.3 1.5 8.5 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1845) IZUMO PF15005.6 ORY20335.1 - 0.66 10.5 7.1 0.17 12.4 1.1 2.6 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated DUF148 PF02520.17 ORY20335.1 - 0.8 9.8 16.3 2.7 8.1 4.1 3.3 2 1 1 3 3 3 0 Domain of unknown function DUF148 Baculo_PEP_C PF04513.12 ORY20335.1 - 1 9.4 25.9 0.62 10.1 3.3 3.0 3 0 0 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 ORY20335.1 - 1.1 9.3 13.4 1.8 8.6 1.4 3.3 3 2 0 3 3 2 0 Protein of unknown function (DUF1664) SseC PF04888.12 ORY20335.1 - 1.7 8.2 10.8 0.096 12.3 1.1 2.5 2 1 0 2 2 2 0 Secretion system effector C (SseC) like family Syntaxin-6_N PF09177.11 ORY20335.1 - 1.7 9.2 10.7 1 10.0 1.5 3.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal IFT57 PF10498.9 ORY20335.1 - 2.3 7.1 14.8 1 8.3 3.9 2.9 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 Exonuc_VII_L PF02601.15 ORY20335.1 - 2.4 7.6 10.4 2.8 7.4 2.5 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit Use1 PF09753.9 ORY20335.1 - 4.5 6.9 14.2 3.8 7.2 3.5 2.4 2 0 0 2 2 2 0 Membrane fusion protein Use1 XhlA PF10779.9 ORY20335.1 - 5.1 7.4 10.8 3.2 8.0 1.4 3.2 2 0 0 2 2 2 0 Haemolysin XhlA DUF2203 PF09969.9 ORY20335.1 - 6.2 7.6 6.9 47 4.7 0.2 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Ribosomal_L17 PF01196.19 ORY20335.1 - 8 7.4 6.4 3.2 8.7 1.8 2.5 2 2 0 2 2 2 0 Ribosomal protein L17 Pkinase_Tyr PF07714.17 ORY20339.1 - 4.4e-39 134.3 0.0 5.2e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORY20339.1 - 4e-37 128.0 0.0 4.6e-37 127.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 ORY20339.1 - 6.4e-05 22.4 0.0 7.8e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY20339.1 - 0.0018 18.2 1.4 0.0059 16.6 0.2 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY20339.1 - 0.0042 16.1 0.1 0.0067 15.4 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY20339.1 - 0.015 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_C48 PF02902.19 ORY20376.1 - 9.7e-35 120.4 0.6 1.2e-34 120.0 0.6 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 ORY20376.1 - 0.024 13.4 0.9 0.084 11.6 0.4 1.9 2 0 0 2 2 2 0 Vaccinia virus I7 processing peptidase DUF2550 PF10739.9 ORY20376.1 - 0.059 13.4 0.1 0.14 12.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2550) eIF2_C PF09173.11 ORY20380.1 - 5.3e-34 116.3 1.3 1.1e-33 115.4 0.3 1.9 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 ORY20380.1 - 1.4e-16 60.6 0.1 2.2e-16 60.0 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 ORY20380.1 - 6.7e-11 42.4 1.3 1.7e-10 41.1 1.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 ORY20380.1 - 0.0091 15.9 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 ORY20380.1 - 0.0098 15.9 0.1 0.02 14.9 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain DUF1793 PF08760.11 ORY20503.1 - 0.22 12.0 1.9 0.2 12.1 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1793) Fungal_TACC PF12709.7 ORY20503.1 - 0.22 12.0 11.0 0.37 11.3 5.1 3.1 3 0 0 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF3287 PF11690.8 ORY20503.1 - 0.42 10.3 4.8 9.7 5.9 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) Gti1_Pac2 PF09729.9 ORY20532.1 - 1e-05 25.7 2.5 0.00012 22.3 0.0 2.0 2 0 0 2 2 2 1 Gti1/Pac2 family Shugoshin_C PF07557.11 ORY20532.1 - 0.04 13.7 1.8 0.063 13.1 1.8 1.3 1 0 0 1 1 1 0 Shugoshin C terminus SOCS PF12610.8 ORY20532.1 - 0.1 13.0 0.9 0.15 12.4 0.9 1.3 1 0 0 1 1 1 0 Suppressor of cytokine signalling Spermine_synth PF01564.17 ORY20539.1 - 0.094 12.1 0.0 5.4 6.4 0.0 2.0 1 1 1 2 2 2 0 Spermine/spermidine synthase domain Resolvase PF00239.21 ORY20541.1 - 4.1e-16 59.4 0.0 7e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Resolvase, N terminal domain THF_DHG_CYH PF00763.23 ORY20541.1 - 0.14 12.5 0.1 0.18 12.1 0.1 1.4 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Tab2_like PF06485.11 ORY20542.1 - 0.11 12.0 0.1 0.12 11.9 0.1 1.0 1 0 0 1 1 1 0 RNA-binding protein Tab2/Atab2 Resolvase PF00239.21 ORY20544.1 - 3e-16 59.8 0.1 6.9e-16 58.7 0.1 1.7 1 1 0 1 1 1 1 Resolvase, N terminal domain DUF4600 PF15372.6 ORY20544.1 - 0.029 14.8 0.1 3.7 8.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) Use1 PF09753.9 ORY20580.1 - 0.13 12.0 1.5 0.15 11.7 1.5 1.0 1 0 0 1 1 1 0 Membrane fusion protein Use1 Resolvase PF00239.21 ORY20715.1 - 8.3e-20 71.4 0.1 1.4e-19 70.6 0.1 1.4 1 0 0 1 1 1 1 Resolvase, N terminal domain TMEM52 PF14979.6 ORY20758.1 - 0.022 14.7 0.5 1.4 8.8 0.2 2.4 2 0 0 2 2 2 0 Transmembrane 52 SH3_9 PF14604.6 ORY20758.1 - 0.027 14.3 0.6 0.038 13.8 0.0 1.5 2 0 0 2 2 2 0 Variant SH3 domain SH3_1 PF00018.28 ORY20758.1 - 0.035 13.7 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 SH3 domain DUF3450 PF11932.8 ORY20758.1 - 0.041 13.2 1.6 0.069 12.4 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) V-SNARE PF05008.15 ORY20758.1 - 0.55 10.6 7.8 1.2 9.6 0.5 3.7 2 1 2 4 4 4 0 Vesicle transport v-SNARE protein N-terminus SPATA1_C PF15743.5 ORY20758.1 - 3.2 7.8 7.0 1.5 8.9 2.7 2.2 2 0 0 2 2 2 0 Spermatogenesis-associated C-terminus DUF3797 PF12677.7 ORY20759.1 - 0.015 15.2 3.1 1 9.3 3.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF3797) DUF3039 PF11238.8 ORY20759.1 - 0.035 13.9 2.3 0.048 13.4 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) DDE_1 PF03184.19 ORY20760.1 - 0.095 12.4 0.0 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 DDE superfamily endonuclease PAN_4 PF14295.6 ORY20841.1 - 1.6e-09 37.5 9.3 0.02 14.8 0.1 4.4 4 0 0 4 4 4 3 PAN domain PAN_1 PF00024.26 ORY20841.1 - 0.00012 22.0 17.1 0.00043 20.2 0.2 4.5 2 2 2 4 4 4 1 PAN domain PAN_3 PF08277.12 ORY20841.1 - 0.00016 21.4 15.1 0.2 11.5 0.1 4.4 4 0 0 4 4 4 3 PAN-like domain Defensin_big PF14862.6 ORY20841.1 - 0.67 10.3 3.4 38 4.7 0.2 3.2 2 0 0 2 2 2 0 Big defensin MANEC PF07502.14 ORY20841.1 - 2.7 8.3 12.7 8.8 6.7 0.1 4.1 4 0 0 4 4 4 0 MANEC domain PAN_2 PF08276.11 ORY20841.1 - 3 8.0 17.6 6.3 7.0 0.1 4.2 4 0 0 4 4 4 0 PAN-like domain AFP PF02420.15 ORY20841.1 - 6.5 7.5 8.5 27 5.6 0.1 3.8 3 0 0 3 3 3 0 Insect antifreeze protein repeat BRE1 PF08647.11 ORY20919.1 - 0.23 11.5 14.7 0.073 13.1 5.4 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase CC2-LZ PF16516.5 ORY20919.1 - 0.86 10.0 7.8 0.89 10.0 0.9 2.6 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4200 PF13863.6 ORY20919.1 - 1.5 9.2 9.7 5.4 7.5 4.6 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) LMBR1 PF04791.16 ORY20919.1 - 3.6 6.4 5.3 4.7 6.0 5.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein MCU PF04678.13 ORY20919.1 - 5.7 7.0 8.9 7.3 6.6 0.8 2.3 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Per1 PF04080.13 ORY20964.1 - 5.6 6.7 17.4 0.38 10.5 8.5 2.3 1 1 2 3 3 3 0 Per1-like family F-box PF00646.33 ORY21033.1 - 0.0031 17.4 1.2 0.024 14.5 0.2 2.5 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 ORY21033.1 - 0.041 13.8 0.1 0.44 10.4 0.0 2.3 2 0 0 2 2 2 0 F-box zf-CCHC_3 PF13917.6 ORY21078.1 - 4e-14 52.3 1.1 4e-14 52.3 1.1 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 ORY21078.1 - 0.05 13.7 1.1 0.081 13.0 1.1 1.3 1 0 0 1 1 1 0 Zinc knuckle BUD22 PF09073.10 ORY21078.1 - 1.1 8.6 37.6 1.2 8.3 37.6 1.1 1 0 0 1 1 1 0 BUD22 Macoilin PF09726.9 ORY21078.1 - 1.9 6.9 31.5 2 6.9 31.5 1.0 1 0 0 1 1 1 0 Macoilin family Ribosomal_L6e PF01159.19 ORY21079.1 - 4.3e-35 120.6 0.4 4.3e-35 120.6 0.4 1.4 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 ORY21079.1 - 4e-06 27.0 0.3 1e-05 25.7 0.3 1.8 1 0 0 1 1 1 1 Ribosomal protein L6, N-terminal domain DNA_pol_A_exoN PF18305.1 ORY21079.1 - 0.085 13.2 0.1 0.16 12.2 0.1 1.5 1 1 0 1 1 1 0 3' to 5' exonuclease C-terminal domain CorA PF01544.18 ORY21081.1 - 3.7e-27 95.4 0.0 4.1e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein TIR_2 PF13676.6 ORY21084.1 - 1.8e-07 31.7 0.0 2.6e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 ORY21084.1 - 0.0036 17.1 0.0 0.0059 16.4 0.0 1.3 1 0 0 1 1 1 1 TIR domain NACHT PF05729.12 ORY21085.1 - 0.0039 17.1 0.0 0.0049 16.8 0.0 1.2 1 0 0 1 1 1 1 NACHT domain EzrA PF06160.12 ORY21086.1 - 0.1 10.7 0.0 0.12 10.5 0.0 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Ank_4 PF13637.6 ORY21087.1 - 4.7e-20 71.7 0.0 1.6e-09 38.1 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY21087.1 - 7.1e-18 64.2 0.3 6.1e-05 23.3 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 ORY21087.1 - 3.7e-17 62.7 0.0 7.5e-17 61.7 0.0 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY21087.1 - 1.2e-15 56.0 0.0 0.00053 20.2 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 ORY21087.1 - 4.2e-10 39.7 0.1 0.00048 20.4 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) HTH_6 PF01418.17 ORY21087.1 - 0.0015 18.5 0.1 0.0023 17.9 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain, rpiR family TM1506 PF08973.10 ORY21087.1 - 0.041 13.5 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1893) Ank_2 PF12796.7 ORY21088.1 - 5.3e-34 116.7 3.4 2.7e-20 72.7 0.4 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY21088.1 - 1.1e-29 102.4 2.2 1.7e-10 41.2 0.1 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY21088.1 - 1e-20 71.6 0.5 6.4e-06 26.1 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 ORY21088.1 - 2.6e-20 72.2 0.7 3.2e-10 40.1 0.1 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY21088.1 - 4.1e-20 71.3 6.3 2.6e-07 30.8 0.2 4.0 4 0 0 4 4 4 4 Ankyrin repeat IgaA PF07095.11 ORY21088.1 - 0.17 9.9 1.7 3.2 5.6 0.1 2.0 2 0 0 2 2 2 0 Intracellular growth attenuator protein IgaA Glyco_hydro_76 PF03663.14 ORY21089.1 - 5.7e-50 170.9 12.1 1e-49 170.0 12.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_127 PF07944.12 ORY21089.1 - 0.014 13.9 0.6 0.029 12.9 0.2 1.8 2 1 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_88 PF07470.13 ORY21089.1 - 0.074 12.1 13.6 0.12 11.5 6.3 3.5 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.13 ORY21089.1 - 0.28 10.7 4.7 0.78 9.2 0.1 2.8 3 0 0 3 3 3 0 D-glucuronyl C5-epimerase C-terminus Phage_HK97_TLTM PF06120.11 ORY21090.1 - 0.24 10.5 0.4 0.39 9.9 0.4 1.2 1 0 0 1 1 1 0 Tail length tape measure protein TrbL PF04610.14 ORY21090.1 - 6.2 6.5 10.2 2.8 7.6 6.7 2.1 2 1 1 3 3 3 0 TrbL/VirB6 plasmid conjugal transfer protein Glyco_hydro_76 PF03663.14 ORY21091.1 - 3.7e-17 62.9 10.6 1.9e-16 60.5 10.6 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 PPR_2 PF13041.6 ORY21091.1 - 0.014 15.6 0.1 6.4 7.0 0.0 2.5 2 0 0 2 2 2 0 PPR repeat family Glyco_hydro_76 PF03663.14 ORY21092.1 - 2.2e-10 40.6 6.0 2.7e-10 40.3 6.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Sensor_TM1 PF13755.6 ORY21148.1 - 0.034 13.9 0.2 0.089 12.5 0.2 1.6 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain PDR_assoc PF08370.11 ORY21149.1 - 4.2 7.2 7.2 3.2 7.6 1.1 2.2 1 1 1 2 2 2 0 Plant PDR ABC transporter associated GLE1 PF07817.13 ORY21151.1 - 0.021 14.1 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 GLE1-like protein ATP-synt_C PF00137.21 ORY21205.1 - 2.4e-06 27.8 10.9 7.7e-06 26.2 10.9 1.7 1 1 0 1 1 1 1 ATP synthase subunit C Oxidored_q2 PF00420.24 ORY21206.1 - 5.4e-07 29.2 10.1 6.3e-07 29.0 10.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Herpes_LMP1 PF05297.11 ORY21206.1 - 1.4 8.1 8.4 1.3 8.1 8.4 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) TMEM100 PF16311.5 ORY21206.1 - 2.1 7.9 4.5 2.9 7.5 4.5 1.2 1 0 0 1 1 1 0 Transmembrane protein 100 Ac76 PF05814.11 ORY21206.1 - 2.8 8.0 9.4 2.3 8.3 7.6 1.7 1 1 1 2 2 2 0 Orf76 (Ac76) RseC_MucC PF04246.12 ORY21206.1 - 7 6.6 10.3 2.5 8.1 0.6 2.1 1 1 1 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Oxidored_q3 PF00499.20 ORY21207.1 - 1.5e-18 66.9 27.6 1.9e-18 66.6 27.6 1.2 1 0 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Proton_antipo_M PF00361.20 ORY21208.1 - 4.9e-68 229.5 30.1 4.9e-68 229.5 30.1 2.6 2 0 0 2 2 2 1 Proton-conducting membrane transporter Proton_antipo_N PF00662.20 ORY21208.1 - 2.3e-18 66.0 2.9 2.3e-18 66.0 2.9 3.3 3 0 0 3 3 3 1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus NADH5_C PF06455.11 ORY21208.1 - 6.8e-08 32.3 13.5 1.2e-05 24.9 6.0 4.1 3 2 2 5 5 5 2 NADH dehydrogenase subunit 5 C-terminus Proton_antipo_M PF00361.20 ORY21209.1 - 2.8e-71 240.1 27.7 2.8e-71 240.1 27.7 2.1 1 1 0 1 1 1 1 Proton-conducting membrane transporter Proton_antipo_M PF00361.20 ORY21210.1 - 2.4e-51 174.7 30.0 2.4e-51 174.7 30.0 2.2 2 0 0 2 2 2 1 Proton-conducting membrane transporter Oxidored_q4 PF00507.19 ORY21211.1 - 6.1e-22 77.6 8.6 7.1e-22 77.4 8.0 1.4 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Cytochrome_B PF00033.19 ORY21212.1 - 2.8e-67 226.2 16.9 6.7e-67 225.0 16.9 1.6 1 0 0 1 1 1 1 Cytochrome b/b6/petB Cytochrom_B_N_2 PF13631.6 ORY21212.1 - 1.6e-35 122.6 9.3 1.6e-35 122.6 9.3 2.3 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Cytochrom_B_C PF00032.17 ORY21212.1 - 1.2e-34 118.6 4.0 1.2e-34 118.6 4.0 2.8 2 1 0 2 2 2 1 Cytochrome b(C-terminal)/b6/petD COX2 PF00116.20 ORY21213.1 - 8.1e-55 183.9 0.1 1.6e-54 182.9 0.0 1.5 2 0 0 2 2 2 1 Cytochrome C oxidase subunit II, periplasmic domain COX2_TM PF02790.15 ORY21213.1 - 2.7e-20 72.3 1.3 6.4e-20 71.1 1.3 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain ATP-synt_A PF00119.20 ORY21214.1 - 4e-35 121.7 32.8 4.9e-35 121.4 32.8 1.0 1 0 0 1 1 1 1 ATP synthase A chain Ferlin_C PF16165.5 ORY21214.1 - 0.46 10.4 5.6 1.4 8.9 5.6 1.9 1 0 0 1 1 1 0 Ferlin C-terminus NADHdh PF00146.21 ORY21215.1 - 1.1e-76 258.1 27.1 1.7e-76 257.4 27.1 1.3 1 1 0 1 1 1 1 NADH dehydrogenase LRR_6 PF13516.6 ORY21287.1 - 0.095 12.8 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 Leucine Rich repeat Thia_YuaJ PF09515.10 ORY21341.1 - 0.014 15.4 1.3 0.039 14.0 1.2 1.7 1 1 0 1 1 1 0 Thiamine transporter protein (Thia_YuaJ) Peptidase_M43 PF05572.13 ORY21342.1 - 1.2e-06 28.5 1.8 1.2e-06 28.5 1.8 1.5 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Peptidase_C24 PF03510.14 ORY21381.1 - 0.013 16.0 0.2 0.016 15.7 0.2 1.1 1 0 0 1 1 1 0 2C endopeptidase (C24) cysteine protease family Tom37 PF10568.9 ORY21454.1 - 4.5e-21 75.5 0.0 7.4e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 ORY21454.1 - 1.8e-16 59.7 0.0 3.8e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 ORY21454.1 - 4.9e-13 49.7 0.0 9e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 ORY21454.1 - 1.2e-08 34.9 0.0 3e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY21454.1 - 0.00016 21.8 0.0 0.00033 20.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY21454.1 - 0.0011 19.1 0.0 0.0021 18.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Lipase_GDSL PF00657.22 ORY21455.1 - 4.3e-13 49.7 0.3 6.7e-13 49.1 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY21455.1 - 3.3e-07 30.9 2.4 9.7e-07 29.3 2.4 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY21456.1 - 1.1e-11 45.1 0.2 2e-11 44.3 0.2 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY21456.1 - 5.6e-05 23.6 1.2 0.00029 21.3 1.2 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PEP_mutase PF13714.6 ORY21456.1 - 0.12 11.8 1.6 0.22 10.9 1.6 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase DUF4865 PF16157.5 ORY21456.1 - 0.17 11.8 0.0 0.29 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4865) Gemini_coat PF00844.18 ORY21562.1 - 0.025 14.0 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Geminivirus coat protein/nuclear export factor BR1 family Mannosyl_trans2 PF04188.13 ORY21563.1 - 0.0046 16.3 0.2 0.0069 15.7 0.2 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) zf-CCHC PF00098.23 ORY21564.1 - 3.2e-05 23.8 3.6 5.5e-05 23.0 3.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 ORY21564.1 - 0.0077 16.1 0.8 0.019 14.8 0.8 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 ORY21564.1 - 1.6 8.6 3.8 2.9 7.8 3.8 1.4 1 0 0 1 1 1 0 Zinc knuckle Tektin PF03148.14 ORY21564.1 - 2.1 7.0 8.7 0.11 11.2 3.3 1.5 2 0 0 2 2 2 0 Tektin family Cwf_Cwc_15 PF04889.12 ORY21564.1 - 4.6 6.9 16.1 5.5 6.6 8.3 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF4169 PF13770.6 ORY21565.1 - 0.011 16.0 3.1 0.019 15.3 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4169) U1snRNP70_N PF12220.8 ORY21565.1 - 0.21 12.3 2.0 0.25 12.0 2.0 1.1 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Caprin-1_C PF12287.8 ORY21565.1 - 1.1 9.4 4.5 1.2 9.2 4.5 1.2 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term Nsp1_C PF05064.13 ORY21568.1 - 0.00018 21.3 5.6 0.00018 21.3 5.6 10.7 7 4 3 12 12 12 2 Nsp1-like C-terminal region HrpB7 PF09486.10 ORY21568.1 - 0.00019 21.9 0.7 0.00019 21.9 0.7 9.8 5 3 3 10 10 9 4 Bacterial type III secretion protein (HrpB7) CENP-F_leu_zip PF10473.9 ORY21568.1 - 0.0015 18.6 14.0 0.0057 16.7 1.6 14.2 7 5 7 14 14 12 6 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Vps51 PF08700.11 ORY21568.1 - 0.0016 18.5 2.1 0.0016 18.5 2.1 9.3 12 3 0 12 12 12 1 Vps51/Vps67 HSBP1 PF06825.12 ORY21568.1 - 0.003 17.4 7.9 0.31 10.9 0.1 5.5 5 0 0 5 5 5 1 Heat shock factor binding protein 1 APG6_N PF17675.1 ORY21568.1 - 0.0051 17.3 20.9 0.0078 16.7 7.3 13.4 4 3 6 12 12 9 4 Apg6 coiled-coil region DUF4472 PF14739.6 ORY21568.1 - 0.01 16.5 4.1 0.01 16.5 4.1 13.1 7 4 6 13 13 11 0 Domain of unknown function (DUF4472) ATG16 PF08614.11 ORY21568.1 - 0.08 13.2 177.7 0.051 13.8 15.6 11.4 4 1 5 10 10 10 0 Autophagy protein 16 (ATG16) Mce4_CUP1 PF11887.8 ORY21568.1 - 0.13 11.7 13.9 0.25 10.8 2.1 3.7 3 0 0 3 3 3 0 Cholesterol uptake porter CUP1 of Mce4, putative Fez1 PF06818.15 ORY21568.1 - 0.19 12.2 142.0 0.27 11.7 18.6 9.1 3 1 6 9 9 9 0 Fez1 Tup_N PF08581.10 ORY21568.1 - 0.21 11.9 0.1 0.21 11.9 0.1 11.7 10 3 3 14 14 14 0 Tup N-terminal YvrJ PF12841.7 ORY21568.1 - 2.4 7.8 4.9 44 3.7 0.1 3.7 3 0 0 3 3 3 0 YvrJ protein family FliJ PF02050.16 ORY21568.1 - 3.5 7.9 135.4 0.014 15.6 18.1 12.7 9 3 2 12 12 12 0 Flagellar FliJ protein CBFD_NFYB_HMF PF00808.23 ORY21571.1 - 4e-27 94.3 0.2 6.4e-27 93.6 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY21571.1 - 2.8e-05 24.5 0.1 3.4e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORY21571.1 - 0.00089 19.3 0.0 0.0012 19.0 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 ORY21571.1 - 0.0049 16.9 0.0 0.0098 15.9 0.0 1.5 1 1 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.13 ORY21571.1 - 0.038 14.5 0.0 0.067 13.7 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-18kDa PF02269.16 ORY21571.1 - 0.041 13.9 0.0 0.053 13.6 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Aminotran_5 PF00266.19 ORY21572.1 - 2e-49 168.5 0.0 3.5e-38 131.5 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ORY21572.1 - 0.00018 20.1 0.2 0.00065 18.3 0.0 1.8 1 1 1 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ORY21572.1 - 0.00023 20.4 0.0 0.00037 19.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Synapsin_N PF10581.9 ORY21572.1 - 0.22 11.5 0.0 0.52 10.3 0.0 1.5 1 0 0 1 1 1 0 Synapsin N-terminal FecCD PF01032.18 ORY21575.1 - 0.37 9.8 2.5 0.12 11.3 0.2 1.4 2 0 0 2 2 2 0 FecCD transport family MFS_1 PF07690.16 ORY21576.1 - 8.6e-21 74.2 33.6 8.6e-21 74.2 33.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 ORY21576.1 - 2.7e-07 29.5 13.4 2.7e-07 29.5 13.4 2.1 3 1 0 3 3 3 1 MFS/sugar transport protein MFS_1 PF07690.16 ORY21578.1 - 2.4e-29 102.4 30.5 2.4e-29 102.4 30.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 ORY21578.1 - 1.3e-12 47.0 4.3 1.3e-12 47.0 4.3 2.9 3 1 1 4 4 4 1 MFS/sugar transport protein OATP PF03137.20 ORY21578.1 - 0.0036 15.7 1.8 0.0036 15.7 1.8 3.3 2 1 2 4 4 4 1 Organic Anion Transporter Polypeptide (OATP) family DUF3094 PF11293.8 ORY21578.1 - 5 6.9 5.4 27 4.6 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3094) MFS_1 PF07690.16 ORY21579.1 - 9.2e-26 90.6 37.8 9.2e-26 90.6 37.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY21579.1 - 3.3e-07 29.2 11.0 3.3e-07 29.2 11.0 2.4 2 1 0 2 2 2 1 MFS/sugar transport protein DUF2417 PF10329.9 ORY21579.1 - 5.4 6.4 8.5 0.12 11.7 0.8 2.1 3 0 0 3 3 3 0 Region of unknown function (DUF2417) Beta-lactamase PF00144.24 ORY21580.1 - 1.7e-34 119.5 1.9 8.2e-34 117.3 1.9 1.8 1 1 0 1 1 1 1 Beta-lactamase Ribosomal_L14e PF01929.17 ORY21583.1 - 3.3e-31 107.6 4.3 4.8e-31 107.1 4.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 ORY21583.1 - 5.4e-05 23.0 3.4 0.00013 21.8 3.4 1.7 1 0 0 1 1 1 1 KOW motif ATPgrasp_TupA PF14305.6 ORY21583.1 - 0.037 13.8 0.1 0.044 13.6 0.1 1.2 1 0 0 1 1 1 0 TupA-like ATPgrasp WD40 PF00400.32 ORY21584.1 - 4.6e-10 39.9 0.1 0.0025 18.6 0.0 4.2 3 0 0 3 3 3 3 WD domain, G-beta repeat PACT_coil_coil PF10495.9 ORY21585.1 - 6.3e-11 42.7 0.0 6.3e-11 42.7 0.0 4.8 4 0 0 4 4 4 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Spc7 PF08317.11 ORY21585.1 - 0.0011 17.9 16.9 0.0011 17.9 16.9 17.3 6 3 12 18 18 18 6 Spc7 kinetochore protein Golgin_A5 PF09787.9 ORY21585.1 - 0.0028 17.2 1.2 0.0028 17.2 1.2 17.0 5 3 14 19 19 19 3 Golgin subfamily A member 5 DUF1664 PF07889.12 ORY21585.1 - 0.0035 17.4 1.4 0.0035 17.4 1.4 16.7 16 4 7 23 23 23 5 Protein of unknown function (DUF1664) Laminin_II PF06009.12 ORY21585.1 - 0.012 15.6 0.9 0.012 15.6 0.9 15.3 12 4 4 17 17 17 0 Laminin Domain II LpxI_N PF17930.1 ORY21585.1 - 0.095 12.6 0.1 0.47 10.3 0.1 2.3 1 0 0 1 1 1 0 LpxI N-terminal domain SPATA1_C PF15743.5 ORY21633.1 - 0.0032 17.5 3.6 0.0051 16.9 3.6 1.2 1 0 0 1 1 1 1 Spermatogenesis-associated C-terminus DUF3015 PF11220.8 ORY21633.1 - 0.012 15.5 1.2 0.033 14.1 1.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) DUF4355 PF14265.6 ORY21633.1 - 0.095 12.9 7.7 0.18 12.0 7.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF812 PF05667.11 ORY21633.1 - 0.13 11.1 7.8 0.19 10.6 7.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FlaC_arch PF05377.11 ORY21633.1 - 0.42 11.0 2.2 2.7 8.5 0.1 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 ORY21633.1 - 3.4 6.8 6.1 5.6 6.1 6.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein Dimer_Tnp_hAT PF05699.14 ORY21635.1 - 0.0021 17.8 0.1 0.0044 16.8 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Wbp11 PF09429.10 ORY21683.1 - 0.048 14.1 1.0 0.048 14.1 1.0 1.8 2 0 0 2 2 2 0 WW domain binding protein 11 Peptidase_C48 PF02902.19 ORY21684.1 - 1.5e-13 51.1 0.2 3.5e-13 49.9 0.2 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF5370 PF17340.2 ORY21684.1 - 0.063 13.2 0.3 0.31 11.0 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5370) TRAM_LAG1_CLN8 PF03798.16 ORY21760.1 - 7e-12 45.5 15.3 3e-09 36.9 9.2 2.1 1 1 1 2 2 2 2 TLC domain SPC12 PF06645.13 ORY21760.1 - 0.06 13.4 10.3 1.5 9.0 0.4 2.2 1 1 1 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Zn_clus PF00172.18 ORY21761.1 - 4.9e-06 26.6 26.4 0.00065 19.8 10.0 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY21761.1 - 0.0079 15.2 0.7 0.018 14.1 0.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ferric_reduct PF01794.19 ORY21809.1 - 7.4e-18 64.9 7.5 7.4e-18 64.9 7.5 3.5 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ORY21809.1 - 1.9e-10 40.8 0.0 4.9e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 ORY21809.1 - 0.0013 18.9 0.0 0.0027 17.8 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Homeodomain PF00046.29 ORY21842.1 - 3.6e-07 29.9 0.1 1e-06 28.5 0.1 1.8 1 0 0 1 1 1 1 Homeodomain YscO-like PF16789.5 ORY21842.1 - 0.05 13.6 6.7 0.97 9.4 0.9 2.8 1 1 0 2 2 2 0 YscO-like protein KxDL PF10241.9 ORY21842.1 - 0.088 13.1 0.9 0.37 11.1 0.9 2.1 1 0 0 1 1 1 0 Uncharacterized conserved protein Plavaka PF18759.1 ORY21843.1 - 5.3e-26 91.6 0.0 6.2e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase OPT PF03169.15 ORY21846.1 - 1.7e-105 354.0 43.8 3.8e-91 306.6 26.0 2.0 2 0 0 2 2 2 2 OPT oligopeptide transporter protein ZYG-11_interact PF05884.12 ORY21846.1 - 0.059 12.8 2.4 0.72 9.2 0.1 2.5 2 0 0 2 2 2 0 Interactor of ZYG-11 TPR_12 PF13424.6 ORY21954.1 - 1.7e-30 105.1 5.6 2.5e-11 43.7 0.0 4.7 3 2 2 5 5 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 ORY21954.1 - 1.7e-21 75.4 0.0 3.4e-08 33.1 0.3 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY21954.1 - 2.1e-11 43.0 8.6 0.0025 17.8 0.0 6.0 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORY21954.1 - 4.2e-11 42.2 12.1 1.7e-06 27.5 0.1 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY21954.1 - 3.1e-09 36.3 7.6 0.018 15.2 0.3 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY21954.1 - 7e-06 25.7 0.7 0.072 13.1 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TIR_2 PF13676.6 ORY21954.1 - 5.3e-05 23.8 0.0 0.00011 22.8 0.0 1.5 1 0 0 1 1 1 1 TIR domain TPR_MalT PF17874.1 ORY21954.1 - 0.00015 21.3 0.0 0.31 10.4 0.0 2.3 2 0 0 2 2 2 2 MalT-like TPR region TPR_11 PF13414.6 ORY21954.1 - 0.00051 19.7 3.3 0.53 10.0 0.0 3.5 2 1 1 3 3 3 2 TPR repeat NB-ARC PF00931.22 ORY21954.1 - 0.0021 17.3 0.7 0.066 12.4 1.2 2.6 1 1 1 2 2 2 1 NB-ARC domain ParA PF10609.9 ORY21954.1 - 0.0022 17.5 0.7 0.036 13.5 0.6 2.2 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase AAA_16 PF13191.6 ORY21954.1 - 0.003 17.9 0.0 0.0094 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain TPR_17 PF13431.6 ORY21954.1 - 0.012 15.9 0.1 2.2 8.9 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_14 PF13173.6 ORY21954.1 - 0.017 15.2 0.1 0.064 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ORY21954.1 - 0.033 13.9 0.1 0.073 12.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF627 PF04781.12 ORY21954.1 - 0.036 14.1 0.6 0.24 11.4 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF627) TPR_16 PF13432.6 ORY21954.1 - 0.052 14.2 0.0 0.87 10.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ABC_tran PF00005.27 ORY21954.1 - 0.08 13.5 0.1 0.24 11.9 0.1 1.8 1 0 0 1 1 1 0 ABC transporter CbiA PF01656.23 ORY21954.1 - 0.18 11.9 0.0 1.8 8.7 0.3 2.4 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain TPR_14 PF13428.6 ORY21954.1 - 0.19 12.6 0.0 21 6.3 0.0 3.8 4 0 0 4 4 2 0 Tetratricopeptide repeat DUF885 PF05960.11 ORY21955.1 - 0.026 14.2 0.5 0.037 13.7 0.5 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DUF4335 PF14233.6 ORY21955.1 - 0.035 14.0 0.7 0.053 13.4 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) Metal_resist PF13801.6 ORY21955.1 - 0.43 10.8 7.7 0.56 10.4 6.8 1.6 2 0 0 2 2 2 0 Heavy-metal resistance GST_C_2 PF13410.6 ORY22040.1 - 0.089 12.8 0.0 0.42 10.7 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Helicase_C PF00271.31 ORY22041.1 - 0.054 13.9 0.1 0.095 13.0 0.1 1.5 1 1 0 1 1 1 0 Helicase conserved C-terminal domain IMUP PF15761.5 ORY22044.1 - 0.067 13.9 1.8 0.09 13.5 1.8 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein TIM21 PF08294.11 ORY22045.1 - 0.03 14.2 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 TIM21 RRM_1 PF00076.22 ORY22046.1 - 1.8e-12 46.9 0.0 2.5e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY22046.1 - 0.0014 18.2 0.1 0.0016 18.0 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol_B_exo1 PF03104.19 ORY22047.1 - 6.2e-26 91.3 0.1 1.3e-25 90.3 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 ORY22047.1 - 5e-24 84.8 6.9 6.3e-12 44.9 0.1 3.5 2 1 2 4 4 4 3 DNA polymerase family B zf-C4pol PF14260.6 ORY22047.1 - 1.2e-17 64.1 7.6 2.6e-17 63.0 7.6 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.6 ORY22047.1 - 0.00041 20.4 0.8 0.04 13.9 0.8 2.5 1 1 0 1 1 1 1 RNase_H superfamily DUF4574 PF15141.6 ORY22052.1 - 0.053 13.4 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Casein_kappa PF00997.18 ORY22052.1 - 0.27 11.3 2.4 0.42 10.7 2.2 1.4 1 1 0 1 1 1 0 Kappa casein DNA_pol_B PF00136.21 ORY22054.1 - 9e-145 482.9 0.3 1.3e-144 482.3 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 ORY22054.1 - 5.4e-82 275.6 0.0 1e-81 274.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 ORY22054.1 - 7.1e-18 64.8 7.4 1.3e-17 64.0 7.4 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 ORY22054.1 - 0.002 17.1 0.4 0.0043 16.0 0.4 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 ORY22054.1 - 0.048 13.7 0.4 0.42 10.6 0.4 2.3 1 1 0 1 1 1 0 RNase_H superfamily DUF1476 PF07345.11 ORY22054.1 - 0.071 13.5 0.1 1.8 9.0 0.0 2.7 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF5479 PF17575.2 ORY22054.1 - 0.079 13.5 0.0 0.21 12.2 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5479) DNA_pol_B_exo2 PF10108.9 ORY22054.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Acyl-CoA_dh_1 PF00441.24 ORY22056.1 - 7.4e-40 136.6 1.1 1.2e-39 136.0 1.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY22056.1 - 2.5e-24 85.3 0.1 4.9e-24 84.3 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 ORY22056.1 - 3.6e-22 78.3 0.0 8.1e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 ORY22056.1 - 3.9e-21 75.8 0.0 1.3e-20 74.1 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY22056.1 - 1.2e-07 32.0 0.4 2.1e-07 31.3 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.25 ORY22057.1 - 8.7e-49 166.2 0.0 9.9e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY22057.1 - 1.6e-35 122.7 0.0 1.8e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY22057.1 - 4.6e-05 22.9 0.1 0.00018 20.9 0.1 1.8 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 ORY22057.1 - 0.0099 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 ORY22057.1 - 0.01 15.2 0.0 0.014 14.8 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4708 PF15813.5 ORY22057.1 - 0.013 14.7 0.3 0.023 13.8 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4708) Seadorna_VP7 PF07387.11 ORY22057.1 - 0.052 12.6 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 ORY22057.1 - 0.086 11.6 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase zf-CCCH_3 PF15663.5 ORY22058.1 - 0.013 15.8 1.5 0.11 12.7 1.3 2.1 2 0 0 2 2 2 0 Zinc-finger containing family E2 PF08199.11 ORY22058.1 - 0.014 15.3 0.5 0.085 12.8 0.1 2.2 1 1 1 2 2 2 0 Bacteriophage E2-like protein Torus PF16131.5 ORY22058.1 - 0.16 12.7 0.5 0.37 11.5 0.5 1.6 1 0 0 1 1 1 0 Torus domain zf-CCCH PF00642.24 ORY22058.1 - 8.7 6.4 7.9 5.5 7.0 4.3 2.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PelG PF16933.5 ORY22059.1 - 0.12 11.1 0.0 0.15 10.9 0.0 1.0 1 0 0 1 1 1 0 Putative exopolysaccharide Exporter (EPS-E) ADIP PF11559.8 ORY22060.1 - 2.7e-08 34.0 51.8 0.0044 17.1 12.7 4.7 2 1 3 5 5 4 3 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.7 ORY22060.1 - 8.5e-07 29.2 45.0 0.02 15.0 8.5 5.1 1 1 4 5 5 5 4 Tropomyosin like DUF4200 PF13863.6 ORY22060.1 - 1.2e-05 25.6 39.6 0.018 15.4 13.0 3.7 1 1 3 4 4 4 2 Domain of unknown function (DUF4200) DivIC PF04977.15 ORY22060.1 - 5.5e-05 22.8 52.6 0.62 9.9 0.7 7.9 2 2 6 8 8 8 4 Septum formation initiator bZIP_1 PF00170.21 ORY22060.1 - 0.00016 21.7 46.6 1.5 9.0 1.6 7.0 2 1 6 8 8 8 5 bZIP transcription factor Exonuc_VII_S PF02609.16 ORY22060.1 - 0.00017 21.6 28.8 0.25 11.5 0.1 7.1 5 3 4 9 9 9 2 Exonuclease VII small subunit CALCOCO1 PF07888.11 ORY22060.1 - 0.00022 20.3 39.9 0.0021 17.0 32.7 2.1 1 1 1 2 2 2 2 Calcium binding and coiled-coil domain (CALCOCO1) like Jnk-SapK_ap_N PF09744.9 ORY22060.1 - 0.00034 20.9 40.4 0.31 11.3 5.1 4.3 1 1 3 4 4 4 3 JNK_SAPK-associated protein-1 BLOC1_2 PF10046.9 ORY22060.1 - 0.00039 20.6 43.2 0.31 11.4 8.7 5.2 1 1 4 5 5 5 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 ZapB PF06005.12 ORY22060.1 - 0.0007 20.0 54.9 0.2 12.1 7.2 6.3 1 1 4 5 5 5 4 Cell division protein ZapB bZIP_2 PF07716.15 ORY22060.1 - 0.00075 19.5 46.5 0.47 10.6 2.4 7.9 2 1 5 8 8 8 3 Basic region leucine zipper Tektin PF03148.14 ORY22060.1 - 0.0041 15.9 42.0 0.52 9.0 10.1 3.9 1 1 2 3 3 3 3 Tektin family TMF_DNA_bd PF12329.8 ORY22060.1 - 0.0091 16.0 61.6 0.24 11.4 10.5 6.4 1 1 5 7 7 7 3 TATA element modulatory factor 1 DNA binding DUF4686 PF15742.5 ORY22060.1 - 0.02 14.1 42.1 0.025 13.7 15.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) Spc7 PF08317.11 ORY22060.1 - 0.02 13.8 46.7 0.12 11.2 19.0 3.1 1 1 1 3 3 3 0 Spc7 kinetochore protein KASH_CCD PF14662.6 ORY22060.1 - 0.038 13.8 50.5 0.46 10.3 35.9 3.6 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 ORY22060.1 - 0.043 13.2 45.0 0.16 11.3 29.6 3.2 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding MscS_porin PF12795.7 ORY22060.1 - 0.068 12.7 46.4 0.12 11.9 27.2 2.4 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain XhlA PF10779.9 ORY22060.1 - 0.081 13.1 0.7 0.081 13.1 0.7 6.3 2 1 3 5 5 4 0 Haemolysin XhlA FlaC_arch PF05377.11 ORY22060.1 - 0.087 13.2 45.8 1.1 9.7 0.6 7.1 2 1 6 8 8 8 0 Flagella accessory protein C (FlaC) ATG16 PF08614.11 ORY22060.1 - 0.089 13.0 48.1 2.1 8.5 20.0 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.19 ORY22060.1 - 0.11 10.3 43.3 0.42 8.4 23.8 2.1 1 1 1 2 2 2 0 Myosin tail SHE3 PF17078.5 ORY22060.1 - 0.13 12.0 45.7 0.094 12.4 17.4 3.2 1 1 2 3 3 3 0 SWI5-dependent HO expression protein 3 Uso1_p115_C PF04871.13 ORY22060.1 - 0.13 12.6 42.5 0.36 11.2 3.2 5.1 1 1 5 6 6 6 0 Uso1 / p115 like vesicle tethering protein, C terminal region Golgin_A5 PF09787.9 ORY22060.1 - 0.16 11.4 44.2 0.2 11.1 19.6 3.1 1 1 2 3 3 3 0 Golgin subfamily A member 5 HMMR_N PF15905.5 ORY22060.1 - 0.18 11.3 48.6 1.1 8.7 32.0 2.8 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor N-terminal YabA PF06156.13 ORY22060.1 - 0.19 12.4 40.5 17 6.1 9.6 5.3 1 1 4 5 5 5 0 Initiation control protein YabA Macscav_rec PF03523.13 ORY22060.1 - 0.19 11.6 18.8 10 6.1 0.0 6.5 7 1 0 7 7 6 0 Macrophage scavenger receptor MAD PF05557.13 ORY22060.1 - 0.3 9.4 44.2 2.2 6.5 33.1 2.4 1 1 1 2 2 2 0 Mitotic checkpoint protein Nup54 PF13874.6 ORY22060.1 - 0.31 11.2 34.2 4.1 7.5 6.4 3.6 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 DASH_Dam1 PF08653.10 ORY22060.1 - 0.37 10.6 22.7 7.7 6.4 0.4 6.8 3 1 3 7 7 7 0 DASH complex subunit Dam1 DUF3450 PF11932.8 ORY22060.1 - 0.42 9.9 41.0 1 8.6 8.8 4.3 1 1 3 4 4 4 0 Protein of unknown function (DUF3450) DUF3552 PF12072.8 ORY22060.1 - 0.53 9.7 43.5 0.096 12.1 9.2 3.9 1 1 3 4 4 4 0 Domain of unknown function (DUF3552) Ax_dynein_light PF10211.9 ORY22060.1 - 0.55 10.1 44.9 3.3 7.6 7.3 5.2 1 1 3 4 4 3 0 Axonemal dynein light chain HOOK PF05622.12 ORY22060.1 - 0.57 8.3 41.7 0.013 13.7 15.1 3.0 1 1 2 3 3 3 0 HOOK protein CLZ PF16526.5 ORY22060.1 - 0.62 10.5 37.1 0.22 11.9 6.1 6.0 2 1 4 6 6 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ribonuc_red_sm PF00268.21 ORY22060.1 - 0.74 9.2 10.1 0.24 10.8 2.8 2.5 1 1 2 3 3 3 0 Ribonucleotide reductase, small chain DUF1664 PF07889.12 ORY22060.1 - 0.99 9.5 35.6 1.2 9.1 1.4 4.1 1 1 5 6 6 6 0 Protein of unknown function (DUF1664) Tropomyosin PF00261.20 ORY22060.1 - 1 8.7 40.5 0.41 10.0 6.2 3.2 1 1 2 3 3 3 0 Tropomyosin ERM PF00769.19 ORY22060.1 - 1.6 8.5 37.8 0.14 11.9 19.1 2.7 2 1 1 3 3 2 0 Ezrin/radixin/moesin family HAP1_N PF04849.13 ORY22060.1 - 1.7 7.8 42.8 1 8.5 1.6 2.8 1 1 1 2 2 2 0 HAP1 N-terminal conserved region DUF2730 PF10805.8 ORY22060.1 - 2 8.6 28.3 0.66 10.1 3.9 4.3 2 1 2 4 4 4 0 Protein of unknown function (DUF2730) MbeD_MobD PF04899.12 ORY22060.1 - 2.6 8.2 16.8 7.2 6.8 0.2 5.3 2 1 4 6 6 6 0 MbeD/MobD like CENP-F_leu_zip PF10473.9 ORY22060.1 - 2.8 8.0 48.4 2.7 8.0 1.3 4.4 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4472 PF14739.6 ORY22060.1 - 3.4 8.4 37.3 3.3 8.5 6.0 4.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4472) Leu_zip PF15294.6 ORY22060.1 - 5.6 6.4 43.6 4 6.9 18.5 2.9 1 1 1 2 2 2 0 Leucine zipper HALZ PF02183.18 ORY22060.1 - 7.1 6.9 37.6 2.8 8.2 1.4 7.2 8 0 0 8 8 7 0 Homeobox associated leucine zipper FUSC PF04632.12 ORY22060.1 - 7.2 5.0 6.3 4 5.9 1.6 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family JAKMIP_CC3 PF16034.5 ORY22060.1 - 9.9 6.1 35.3 10 6.0 5.7 4.2 1 1 4 5 5 5 0 JAKMIP CC3 domain DUF1754 PF08555.10 ORY22064.1 - 0.011 16.5 2.5 0.011 16.5 2.5 3.1 4 0 0 4 4 4 0 Eukaryotic family of unknown function (DUF1754) eIF3_subunit PF08597.10 ORY22064.1 - 0.91 9.4 14.2 0.65 9.9 0.5 2.5 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DUF3619 PF12279.8 ORY22064.1 - 1.2 9.5 0.0 1.2 9.5 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3619) ubiquitin PF00240.23 ORY22066.1 - 2.2e-09 36.9 0.0 3.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY22066.1 - 0.00027 20.7 0.0 0.00046 20.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 ORY22066.1 - 0.0049 16.9 0.0 0.011 15.8 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ACCA PF03255.14 ORY22067.1 - 0.06 13.2 6.3 3.3 7.6 0.1 3.0 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ATG16 PF08614.11 ORY22067.1 - 0.32 11.2 9.3 0.053 13.7 2.9 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) FAM76 PF16046.5 ORY22067.1 - 1.5 8.1 12.6 0.31 10.3 7.5 1.9 1 1 1 2 2 2 0 FAM76 protein Spc7 PF08317.11 ORY22067.1 - 2.2 7.1 11.8 16 4.3 11.8 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF848 PF05852.11 ORY22067.1 - 4.6 7.4 8.4 2.8 8.1 4.6 2.4 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Muted PF14942.6 ORY22067.1 - 4.9 7.5 7.8 1.5 9.2 0.2 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein TMF_DNA_bd PF12329.8 ORY22067.1 - 6.4 6.8 16.3 2 8.5 4.7 3.4 2 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding AA_permease_2 PF13520.6 ORY22068.1 - 2.9e-36 125.2 14.7 3.3e-36 125.0 14.7 1.0 1 0 0 1 1 1 1 Amino acid permease LapA_dom PF06305.11 ORY22068.1 - 4.4 7.2 6.6 3.3 7.6 0.4 2.9 2 1 1 3 3 3 0 Lipopolysaccharide assembly protein A domain HTH_55 PF18622.1 ORY22141.1 - 0.1 12.9 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 RctB helix turn helix domain Nsp1_C PF05064.13 ORY22142.1 - 0.00025 20.8 1.3 0.00028 20.7 1.3 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region BLOC1_2 PF10046.9 ORY22142.1 - 0.001 19.4 1.0 0.0013 19.0 1.0 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ZapB PF06005.12 ORY22142.1 - 0.0012 19.2 5.7 0.0016 18.8 5.7 1.3 1 1 0 1 1 1 1 Cell division protein ZapB GAS PF13851.6 ORY22142.1 - 0.0014 18.0 2.9 0.0017 17.7 2.9 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Cluap1 PF10234.9 ORY22142.1 - 0.0019 17.7 1.8 0.002 17.6 1.8 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 Spc29 PF17082.5 ORY22142.1 - 0.0034 17.3 1.2 0.0038 17.1 1.2 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 DUF3450 PF11932.8 ORY22142.1 - 0.0058 16.0 2.1 0.0068 15.7 1.7 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) CASP_C PF08172.12 ORY22142.1 - 0.0059 16.0 2.1 0.0068 15.8 2.1 1.1 1 0 0 1 1 1 1 CASP C terminal TMF_DNA_bd PF12329.8 ORY22142.1 - 0.0074 16.3 1.8 0.0074 16.3 1.8 1.7 1 1 0 2 2 2 1 TATA element modulatory factor 1 DNA binding BST2 PF16716.5 ORY22142.1 - 0.0077 16.8 2.8 0.0099 16.4 2.8 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 Sec34 PF04136.15 ORY22142.1 - 0.0079 16.1 2.0 0.0088 15.9 2.0 1.1 1 0 0 1 1 1 1 Sec34-like family DUF4164 PF13747.6 ORY22142.1 - 0.01 16.1 0.4 0.015 15.6 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) YabA PF06156.13 ORY22142.1 - 0.012 16.2 2.0 0.015 15.9 2.0 1.1 1 0 0 1 1 1 0 Initiation control protein YabA Tropomyosin_1 PF12718.7 ORY22142.1 - 0.013 15.7 3.0 0.018 15.2 3.0 1.4 1 1 0 1 1 1 0 Tropomyosin like CCDC92 PF14916.6 ORY22142.1 - 0.019 14.7 4.6 0.034 13.9 4.4 1.6 1 1 0 1 1 1 0 Coiled-coil domain of unknown function Herpes_UL6 PF01763.16 ORY22142.1 - 0.025 13.1 2.5 0.026 13.1 2.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like HlyD_D23 PF16576.5 ORY22142.1 - 0.026 13.7 1.2 0.029 13.6 1.2 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion DUF948 PF06103.11 ORY22142.1 - 0.027 14.7 0.6 0.037 14.3 0.6 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 ORY22142.1 - 0.029 14.9 4.3 0.039 14.5 4.3 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region Fmp27_WPPW PF10359.9 ORY22142.1 - 0.031 13.1 3.5 0.033 13.1 3.5 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Seryl_tRNA_N PF02403.22 ORY22142.1 - 0.053 13.7 1.8 0.077 13.2 1.2 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain XhlA PF10779.9 ORY22142.1 - 0.07 13.3 2.8 0.14 12.4 2.8 1.5 1 0 0 1 1 1 0 Haemolysin XhlA USP8_interact PF08941.10 ORY22142.1 - 0.1 12.4 2.4 0.12 12.1 2.4 1.1 1 0 0 1 1 1 0 USP8 interacting DUF16 PF01519.16 ORY22142.1 - 0.13 12.7 3.7 0.21 12.1 3.6 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 SlyX PF04102.12 ORY22142.1 - 0.15 12.7 5.1 0.7 10.6 5.1 2.0 1 1 0 1 1 1 0 SlyX CENP-H PF05837.12 ORY22142.1 - 0.15 12.5 4.8 0.19 12.2 4.8 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DivIC PF04977.15 ORY22142.1 - 0.21 11.4 4.7 0.67 9.8 4.4 1.9 1 1 1 2 2 2 0 Septum formation initiator NPV_P10 PF05531.12 ORY22142.1 - 0.22 12.0 2.9 0.63 10.5 3.2 1.7 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 ORY22142.1 - 0.23 11.6 4.3 2.8 8.1 4.4 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family bZIP_2 PF07716.15 ORY22142.1 - 0.61 10.2 3.9 2.9 8.1 1.2 2.3 1 1 1 2 2 2 0 Basic region leucine zipper F-box-like PF12937.7 ORY22143.1 - 0.00069 19.5 0.2 0.002 18.0 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY22143.1 - 0.00089 19.1 0.7 0.003 17.4 0.4 2.2 2 0 0 2 2 2 1 F-box domain Mito_carr PF00153.27 ORY22144.1 - 1.1e-50 169.5 1.3 2.6e-17 62.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3262 PF11660.8 ORY22144.1 - 0.018 15.4 0.4 0.039 14.3 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) UbiA PF01040.18 ORY22144.1 - 0.11 11.7 3.8 0.6 9.4 1.0 2.1 1 1 1 2 2 2 0 UbiA prenyltransferase family Plavaka PF18759.1 ORY22147.1 - 5.3e-26 91.6 0.0 6.2e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase NAD_binding_10 PF13460.6 ORY22150.1 - 3.6e-09 36.8 1.0 6.2e-09 36.0 1.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF640 PF04852.12 ORY22226.1 - 0.034 14.3 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF640) Plavaka PF18759.1 ORY22253.1 - 5.3e-26 91.6 0.0 6.2e-26 91.4 0.0 1.0 1 0 0 1 1 1 1 Plavaka transposase Ribosomal_L31 PF01197.18 ORY22259.1 - 0.009 16.2 0.0 0.011 15.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L31 Complex1_30kDa PF00329.19 ORY22260.1 - 1.2e-47 161.5 0.0 1.6e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit HSP70 PF00012.20 ORY22261.1 - 6.7e-257 853.5 13.6 7.6e-257 853.3 13.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY22261.1 - 9.4e-17 60.8 0.5 3.1e-15 55.8 0.2 2.3 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 ORY22261.1 - 0.0041 16.2 0.7 0.028 13.4 0.4 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 ORY22261.1 - 0.0046 16.3 4.4 0.7 9.1 0.3 3.2 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase FtsA PF14450.6 ORY22261.1 - 0.0095 16.3 6.8 2.4 8.6 0.2 4.1 3 2 0 3 3 3 2 Cell division protein FtsA DUF4624 PF15417.6 ORY22261.1 - 0.089 12.6 1.1 2 8.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4624) FGGY_C PF02782.16 ORY22261.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Radial_spoke_3 PF06098.11 ORY22261.1 - 0.2 10.9 6.6 0.064 12.5 3.6 1.6 2 0 0 2 2 2 0 Radial spoke protein 3 Spa1_C PF18218.1 ORY22261.1 - 7.7 7.0 7.3 5.2 7.5 2.9 2.6 2 1 1 3 3 3 0 Lantibiotic immunity protein Spa1 C-terminal domain ABC_tran PF00005.27 ORY22262.1 - 1.6e-41 142.0 0.3 6.1e-20 72.1 0.0 3.3 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 ORY22262.1 - 7.7e-18 65.3 1.6 4e-05 23.6 0.0 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ORY22262.1 - 1.5e-10 41.4 0.2 0.00044 20.1 0.0 4.9 3 1 0 3 3 3 1 AAA ATPase domain SMC_N PF02463.19 ORY22262.1 - 7.2e-09 35.4 9.9 0.49 9.8 0.0 5.0 5 0 0 5 5 5 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY22262.1 - 3.7e-08 33.0 1.8 0.0091 15.7 0.1 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain ABC_tran_Xtn PF12848.7 ORY22262.1 - 3.6e-07 30.1 14.0 5.6e-06 26.3 12.5 2.5 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.6 ORY22262.1 - 1.1e-05 25.7 0.1 0.063 13.5 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_27 PF13514.6 ORY22262.1 - 0.00022 20.9 4.3 0.18 11.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 ORY22262.1 - 0.00082 19.1 0.0 0.13 12.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 ORY22262.1 - 0.0009 19.8 0.8 0.042 14.3 0.1 4.4 4 1 0 4 4 3 2 AAA domain AAA_18 PF13238.6 ORY22262.1 - 0.0012 19.3 0.6 0.081 13.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 ORY22262.1 - 0.0016 18.4 4.7 0.016 15.1 0.0 3.2 3 0 0 3 3 3 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 ORY22262.1 - 0.0017 17.8 0.0 0.068 12.5 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.6 ORY22262.1 - 0.0047 16.5 0.0 2.5 7.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 ORY22262.1 - 0.006 16.6 0.8 0.051 13.6 0.0 2.8 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_33 PF13671.6 ORY22262.1 - 0.0063 16.7 0.0 0.23 11.6 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ORY22262.1 - 0.02 15.3 0.4 2.8 8.4 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 ORY22262.1 - 0.023 14.6 0.3 1.9 8.4 0.0 2.8 3 0 0 3 3 3 0 NACHT domain AAA_16 PF13191.6 ORY22262.1 - 0.024 15.0 0.0 0.64 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 ORY22262.1 - 0.035 14.5 0.0 1.4 9.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase MukB PF04310.12 ORY22262.1 - 0.037 13.8 0.1 7.1 6.4 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal NTPase_1 PF03266.15 ORY22262.1 - 0.042 13.8 0.0 2 8.3 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.14 ORY22262.1 - 0.099 12.6 0.0 2.4 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 ORY22262.1 - 0.14 12.4 0.9 2.3 8.4 0.0 3.1 3 1 0 3 3 3 0 AAA domain DUF4999 PF16390.5 ORY22262.1 - 0.15 12.3 0.1 0.34 11.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function cobW PF02492.19 ORY22262.1 - 0.26 10.9 5.1 2 7.9 0.1 3.4 4 0 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 ORY22262.1 - 0.26 11.3 7.6 14 5.7 0.2 3.5 3 0 0 3 3 3 0 Helicase HerA, central domain DDHD PF02862.17 ORY22262.1 - 0.6 10.2 3.4 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 DDHD domain STAT_bind PF02864.15 ORY22262.1 - 1 9.9 4.9 2.5 8.7 4.9 1.7 1 0 0 1 1 1 0 STAT protein, DNA binding domain TMPIT PF07851.13 ORY22262.1 - 4.4 6.5 8.1 8 5.6 8.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein 7tm_2 PF00002.24 ORY22263.1 - 1.9e-10 40.4 9.9 2.4e-10 40.1 9.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 ORY22263.1 - 7.3e-10 38.6 16.6 1e-09 38.1 16.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Tmemb_18A PF09771.9 ORY22263.1 - 0.015 15.7 1.1 0.015 15.7 1.1 2.7 3 0 0 3 3 3 0 Transmembrane protein 188 Orbi_VP4 PF05059.12 ORY22263.1 - 0.27 9.2 1.4 0.38 8.7 1.4 1.1 1 0 0 1 1 1 0 Orbivirus VP4 core protein TMEMspv1-c74-12 PF11044.8 ORY22263.1 - 1.7 8.7 4.4 9 6.4 0.0 2.9 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Acetyltransf_1 PF00583.25 ORY22264.1 - 6.9e-15 55.3 0.0 5.1e-08 33.2 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY22264.1 - 1.4e-13 51.0 0.1 1.8e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY22264.1 - 3.6e-08 33.4 0.3 0.0053 16.7 0.1 3.1 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY22264.1 - 1.7e-06 28.0 0.0 0.021 14.9 0.0 2.4 2 0 0 2 2 2 2 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 ORY22264.1 - 0.00026 21.7 0.0 0.12 13.1 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 ORY22264.1 - 0.00044 19.8 0.0 0.089 12.2 0.0 2.2 2 0 0 2 2 2 2 Putative acetyl-transferase PDEase_I PF00233.19 ORY22265.1 - 4.8e-61 206.5 0.0 1.4e-60 205.0 0.0 1.8 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PSII_Pbs31 PF18240.1 ORY22266.1 - 0.015 15.8 0.1 0.026 15.0 0.1 1.5 1 0 0 1 1 1 0 Photosystem II Psb31 protein PHD PF00628.29 ORY22332.1 - 0.32 10.9 4.9 0.65 9.9 4.9 1.5 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 ORY22332.1 - 0.51 10.3 3.8 1.5 8.8 3.8 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DEAD PF00270.29 ORY22333.1 - 2.3e-19 69.8 0.1 5.5e-19 68.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY22333.1 - 5.4e-19 68.6 0.0 7.2e-16 58.5 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 ORY22333.1 - 6.5e-06 26.3 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RecQ_Zn_bind PF16124.5 ORY22333.1 - 5.5e-05 23.8 0.9 0.00015 22.4 0.9 1.8 1 0 0 1 1 1 1 RecQ zinc-binding AhpC-TSA PF00578.21 ORY22333.1 - 0.11 12.4 0.1 17 5.3 0.0 3.1 3 0 0 3 3 3 0 AhpC/TSA family OrsD PF12013.8 ORY22398.1 - 0.82 10.1 7.6 0.18 12.3 2.3 2.5 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D BUD22 PF09073.10 ORY22400.1 - 3.7 6.8 16.2 4.5 6.5 16.2 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 ORY22400.1 - 4 6.8 16.4 5.9 6.2 16.4 1.3 1 0 0 1 1 1 0 SDA1 DUF3952 PF13130.6 ORY22401.1 - 0.13 12.4 0.0 0.25 11.6 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3952) zf-C2H2 PF00096.26 ORY22402.1 - 0.024 15.1 5.8 3.3 8.3 2.0 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY22402.1 - 0.55 11.2 7.0 8 7.6 2.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger TPR_12 PF13424.6 ORY22403.1 - 5.5e-41 138.7 11.9 8.4e-17 61.2 1.0 5.2 2 2 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 ORY22403.1 - 4.1e-35 118.7 0.1 4.2e-08 32.8 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY22403.1 - 4.3e-27 92.0 13.4 4.6e-05 23.2 0.3 6.8 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_8 PF13181.6 ORY22403.1 - 1e-21 75.2 24.2 2e-05 24.5 0.6 6.9 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 ORY22403.1 - 1.6e-18 65.6 19.8 6.8e-05 22.5 0.6 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 ORY22403.1 - 1.9e-16 58.8 7.3 0.0017 18.3 0.0 5.5 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 ORY22403.1 - 1.1e-11 44.5 0.0 1.1 10.2 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TIR_2 PF13676.6 ORY22403.1 - 6.9e-10 39.6 0.0 5.9e-09 36.6 0.0 2.4 2 0 0 2 2 2 1 TIR domain TPR_6 PF13174.6 ORY22403.1 - 5.7e-08 32.9 11.6 0.38 11.5 0.2 5.6 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY22403.1 - 6.9e-08 33.0 0.9 0.0099 16.5 0.5 4.8 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY22403.1 - 1.2e-07 31.6 1.7 1.9 9.0 0.0 6.3 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY22403.1 - 1.4e-07 31.3 5.8 4.5e-06 26.3 2.9 2.9 2 1 0 2 2 2 1 MalT-like TPR region NB-ARC PF00931.22 ORY22403.1 - 1.1e-05 24.8 0.0 2.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.6 ORY22403.1 - 1.5e-05 25.4 7.5 0.0019 18.7 1.8 3.9 2 2 3 5 5 4 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY22403.1 - 0.00029 20.8 17.1 1 9.5 0.1 5.6 7 0 0 7 7 4 2 Fis1 C-terminal tetratricopeptide repeat AAA_22 PF13401.6 ORY22403.1 - 0.00054 20.2 0.0 0.0021 18.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 ORY22403.1 - 0.0011 18.9 0.0 0.0035 17.3 0.0 1.9 2 0 0 2 2 1 1 NACHT domain SHNi-TPR PF10516.9 ORY22403.1 - 0.0015 17.9 4.1 0.36 10.3 0.1 4.6 5 0 0 5 5 5 1 SHNi-TPR AAA_16 PF13191.6 ORY22403.1 - 0.0049 17.3 0.0 0.018 15.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain PPR PF01535.20 ORY22403.1 - 0.012 15.8 0.2 65 4.1 0.0 4.4 4 0 0 4 4 3 0 PPR repeat HTH_Tnp_Mu_2 PF09039.11 ORY22403.1 - 0.034 14.2 0.3 5.1 7.2 0.0 3.6 2 1 2 4 4 4 0 Mu DNA binding, I gamma subdomain TPR_4 PF07721.14 ORY22403.1 - 0.064 13.9 0.0 1.2e+02 3.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 ORY22403.1 - 0.085 12.9 18.5 6.9 6.8 0.6 4.8 2 2 2 4 4 4 0 MIT (microtubule interacting and transport) domain FYRN PF05964.14 ORY22403.1 - 0.12 12.2 0.0 41 4.1 0.0 3.2 3 0 0 3 3 3 0 F/Y-rich N-terminus AAA_25 PF13481.6 ORY22403.1 - 0.19 11.3 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain TPR_21 PF09976.9 ORY22403.1 - 1 9.0 5.9 1.4e+02 2.1 4.5 3.7 2 1 0 2 2 2 0 Tetratricopeptide repeat-like domain DNA_pol_A_exo1 PF01612.20 ORY22404.1 - 1.7e-11 44.2 0.0 3e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Med3 PF11593.8 ORY22404.1 - 0.42 9.8 0.9 0.73 9.0 0.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal F-box-like PF12937.7 ORY22406.1 - 0.067 13.1 1.2 0.28 11.1 0.0 2.7 2 1 0 2 2 2 0 F-box-like MG3 PF17791.1 ORY22406.1 - 0.068 13.4 0.2 0.16 12.2 0.2 1.6 1 0 0 1 1 1 0 Macroglobulin domain MG3 DUF4006 PF13179.6 ORY22452.1 - 0.27 11.2 3.2 0.74 9.8 0.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF4006) IncE PF17627.2 ORY22455.1 - 0.16 12.0 1.8 0.39 10.7 1.8 1.6 1 0 0 1 1 1 0 Inclusion membrane protein E Vma12 PF11712.8 ORY22455.1 - 0.24 11.5 4.6 1.4 9.0 0.1 2.6 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase BTG PF07742.12 ORY22456.1 - 4.4e-25 87.8 0.0 1e-24 86.6 0.0 1.6 1 1 1 2 2 2 1 BTG family Prp19 PF08606.11 ORY22457.1 - 4.5e-31 106.6 3.3 1.2e-30 105.2 3.3 1.8 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 ORY22457.1 - 4.5e-20 71.6 13.3 0.00019 22.2 0.2 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY22457.1 - 2.6e-07 30.8 1.5 0.056 13.8 0.0 4.5 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TMF_TATA_bd PF12325.8 ORY22457.1 - 0.047 13.9 1.3 0.19 12.0 1.2 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Nup160 PF11715.8 ORY22457.1 - 0.13 10.9 0.5 15 4.0 0.0 3.1 2 1 2 4 4 4 0 Nucleoporin Nup120/160 zf-Nse PF11789.8 ORY22457.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DivIC PF04977.15 ORY22457.1 - 0.74 9.6 3.2 1.5 8.6 3.2 1.4 1 0 0 1 1 1 0 Septum formation initiator Ank_4 PF13637.6 ORY22458.1 - 5.5e-11 42.8 0.3 0.013 16.0 0.2 4.7 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Bacteriocin_IIi PF11758.8 ORY22458.1 - 0.048 13.5 0.1 0.048 13.5 0.1 3.8 4 0 0 4 4 4 0 Aureocin-like type II bacteriocin Cytochrom_B559 PF00283.19 ORY22458.1 - 0.54 9.8 0.1 0.54 9.8 0.1 2.0 2 0 0 2 2 2 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits Usp PF00582.26 ORY22459.1 - 1.8e-18 67.4 0.0 2.2e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family zf_UBZ PF18439.1 ORY22461.1 - 0.12 12.0 4.9 1.8 8.2 4.9 2.3 1 1 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-C2H2_11 PF16622.5 ORY22461.1 - 0.47 10.3 0.2 0.47 10.3 0.2 2.6 3 0 0 3 3 3 0 zinc-finger C2H2-type Pex14_N PF04695.13 ORY22517.1 - 0.041 14.5 2.8 0.053 14.2 2.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Rhomboid PF01694.22 ORY22518.1 - 1.3e-07 31.7 2.2 1.6e-07 31.4 2.2 1.2 1 0 0 1 1 1 1 Rhomboid family DUF974 PF06159.13 ORY22520.1 - 1.1e-69 235.0 0.1 1.4e-69 234.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.7 ORY22520.1 - 0.011 15.2 0.8 0.011 15.2 0.8 2.4 3 0 0 3 3 3 0 TRAPP trafficking subunit Trs65 Lebercilin PF15619.6 ORY22521.1 - 0.0005 19.8 7.6 0.00079 19.1 7.6 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease HAP1_N PF04849.13 ORY22521.1 - 0.02 14.1 3.2 0.032 13.4 3.2 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region CEP209_CC5 PF16574.5 ORY22521.1 - 0.021 15.0 2.6 0.035 14.3 2.6 1.2 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 TFIIE-A_C PF11521.8 ORY22521.1 - 0.025 14.8 3.8 0.11 12.8 3.4 2.2 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha DHR10 PF18595.1 ORY22521.1 - 0.039 14.0 3.1 0.064 13.3 3.1 1.3 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Golgin_A5 PF09787.9 ORY22521.1 - 0.041 13.4 1.3 0.07 12.6 1.3 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Tropomyosin_1 PF12718.7 ORY22521.1 - 0.069 13.3 1.9 0.11 12.6 1.9 1.2 1 0 0 1 1 1 0 Tropomyosin like ADIP PF11559.8 ORY22521.1 - 0.076 13.1 4.1 0.15 12.2 4.1 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Tropomyosin PF00261.20 ORY22521.1 - 0.081 12.3 2.0 0.12 11.7 2.0 1.2 1 0 0 1 1 1 0 Tropomyosin DUF489 PF04356.12 ORY22521.1 - 0.14 12.2 0.6 0.22 11.5 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) MAP70 PF07058.11 ORY22521.1 - 0.17 10.6 1.2 0.29 9.8 1.2 1.3 1 0 0 1 1 1 0 Microtubule-associated protein 70 IFT20 PF14931.6 ORY22521.1 - 0.19 11.9 3.6 0.35 11.0 3.6 1.4 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 SlyX PF04102.12 ORY22521.1 - 0.22 12.2 3.2 0.6 10.8 3.1 1.8 1 1 0 1 1 1 0 SlyX TRAF_BIRC3_bd PF16673.5 ORY22521.1 - 0.25 11.2 2.5 0.43 10.4 1.7 1.8 1 1 1 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Spc7 PF08317.11 ORY22521.1 - 0.26 10.1 3.0 0.38 9.6 3.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FliJ PF02050.16 ORY22521.1 - 0.31 11.3 4.5 0.52 10.6 4.5 1.3 1 0 0 1 1 1 0 Flagellar FliJ protein AAA_13 PF13166.6 ORY22521.1 - 0.46 9.1 2.0 0.71 8.4 2.0 1.2 1 0 0 1 1 1 0 AAA domain E1-E2_ATPase PF00122.20 ORY22522.1 - 5.5e-52 175.9 0.7 5.5e-52 175.9 0.7 3.2 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY22522.1 - 9.6e-48 162.3 11.8 1.5e-47 161.7 9.7 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY22522.1 - 3.8e-22 79.6 1.2 8e-21 75.3 1.2 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY22522.1 - 1.1e-20 73.1 0.6 3e-20 71.7 0.1 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 ORY22522.1 - 7e-19 67.7 0.0 1.4e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY22522.1 - 2.9e-07 30.5 1.2 1.4e-05 25.0 1.0 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY22522.1 - 3e-07 31.0 0.0 1.8e-06 28.5 0.0 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF1772 PF08592.11 ORY22522.1 - 0.0048 17.2 3.3 0.12 12.7 0.0 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF1772) zf-C2H2 PF00096.26 ORY22524.1 - 5.3e-08 32.9 11.7 2.6e-05 24.4 4.9 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY22524.1 - 5.4e-07 29.9 9.0 0.0018 18.9 4.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY22524.1 - 1.8e-05 25.0 12.6 0.0051 17.2 0.3 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY22524.1 - 0.0032 17.7 5.8 0.017 15.4 2.8 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY22524.1 - 0.0038 17.6 2.1 0.036 14.5 2.2 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 ORY22524.1 - 0.004 17.4 5.0 0.061 13.7 1.6 2.3 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 ORY22524.1 - 0.0087 16.5 1.2 0.092 13.2 0.5 2.4 1 1 1 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger Rad50_zn_hook PF04423.14 ORY22524.1 - 0.1 12.4 0.4 0.33 10.8 0.1 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif ROS_MUCR PF05443.11 ORY22524.1 - 0.11 12.5 0.5 0.16 12.1 0.1 1.7 2 1 0 2 2 2 0 ROS/MUCR transcriptional regulator protein zf-BED PF02892.15 ORY22524.1 - 0.18 11.8 2.1 0.28 11.2 0.3 2.0 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.6 ORY22524.1 - 0.28 11.2 7.8 0.39 10.8 4.7 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY22525.1 - 4.2e-09 36.4 8.1 7.2e-05 23.0 1.9 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY22525.1 - 6.6e-06 26.3 1.2 6.6e-06 26.3 1.2 2.9 2 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY22525.1 - 0.00017 22.1 9.0 0.036 14.9 0.5 2.3 2 1 0 2 2 2 2 C2H2-type zinc finger GAGA PF09237.11 ORY22525.1 - 0.0002 21.1 0.1 0.00024 20.9 0.1 1.2 1 0 0 1 1 1 1 GAGA factor Zn-ribbon_8 PF09723.10 ORY22525.1 - 0.0042 17.2 0.4 0.0075 16.4 0.4 1.4 1 1 0 1 1 1 1 Zinc ribbon domain IBR PF01485.21 ORY22525.1 - 0.0093 16.2 0.3 0.011 15.9 0.3 1.1 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain zf-C2H2_8 PF15909.5 ORY22525.1 - 0.013 15.8 1.0 0.013 15.8 1.0 1.0 1 0 0 1 1 1 0 C2H2-type zinc ribbon ADK_lid PF05191.14 ORY22525.1 - 0.062 13.3 0.4 0.096 12.7 0.4 1.4 1 1 0 1 1 1 0 Adenylate kinase, active site lid zf_ZIC PF18366.1 ORY22525.1 - 0.081 13.1 1.3 0.081 13.1 1.3 1.8 1 1 1 2 2 2 0 Zic proteins zinc finger domain zf_C2H2_10 PF18414.1 ORY22525.1 - 0.089 12.3 1.3 0.2 11.2 1.3 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger YdjO PF14169.6 ORY22525.1 - 0.2 11.4 1.8 1.1 9.0 1.8 1.9 1 1 0 1 1 1 0 Cold-inducible protein YdjO DUF1936 PF09151.10 ORY22525.1 - 0.21 11.5 4.3 7.8 6.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) zinc_ribbon_5 PF13719.6 ORY22525.1 - 0.31 10.8 0.2 0.31 10.8 0.2 2.1 2 1 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.11 ORY22527.1 - 0.00037 20.4 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 Putative transposase DNA-binding domain CDC45 PF02724.14 ORY22529.1 - 0.037 12.3 9.2 0.048 12.0 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein PI3K_1B_p101 PF10486.9 ORY22529.1 - 2.5 5.8 7.9 3.2 5.4 7.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RRN3 PF05327.11 ORY22529.1 - 2.5 6.5 8.6 3.3 6.2 8.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GATA PF00320.27 ORY22530.1 - 3.2e-08 33.0 11.9 6e-08 32.2 11.9 1.5 1 0 0 1 1 1 1 GATA zinc finger OrfB_Zn_ribbon PF07282.11 ORY22530.1 - 0.5 10.3 4.2 1.1 9.2 4.2 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DGF-1_C PF11040.8 ORY22530.1 - 8.1 6.5 13.7 4 7.5 0.1 3.0 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus OrfB_Zn_ribbon PF07282.11 ORY22531.1 - 0.032 14.2 0.7 0.092 12.7 0.7 1.8 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-C2H2 PF00096.26 ORY22531.1 - 9.2 6.9 12.9 0.27 11.8 2.2 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2 PF00096.26 ORY22532.1 - 0.002 18.5 0.1 0.002 18.5 0.1 2.5 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 ORY22532.1 - 0.022 14.5 0.1 0.057 13.2 0.1 1.8 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 ORY22532.1 - 0.078 13.9 0.3 0.078 13.9 0.3 3.0 2 1 1 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 ORY22532.1 - 0.078 13.3 0.7 0.16 12.3 0.7 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 ORY22532.1 - 0.68 10.4 2.7 0.75 10.3 0.1 2.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 ORY22532.1 - 0.93 9.5 3.3 0.38 10.7 0.1 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-Tim10_DDP PF02953.15 ORY22533.1 - 0.22 11.2 12.3 5 6.8 1.0 4.6 5 1 1 6 6 6 0 Tim10/DDP family zinc finger AJAP1_PANP_C PF15298.6 ORY22533.1 - 0.27 11.4 6.1 3.7 7.7 0.0 3.2 4 1 0 4 4 4 0 AJAP1/PANP C-terminus CFEM PF05730.11 ORY22533.1 - 9.8 6.4 23.1 2.6 8.2 2.9 4.4 3 3 0 3 3 3 0 CFEM domain TMF_TATA_bd PF12325.8 ORY22534.1 - 0.023 14.9 0.5 0.023 14.9 0.5 2.6 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding HOIP-UBA PF16678.5 ORY22534.1 - 2.4 8.1 7.2 1.1 9.3 0.4 2.7 3 0 0 3 3 3 0 HOIP UBA domain pair V_ATPase_I PF01496.19 ORY22534.1 - 4.5 5.1 6.6 0.2 9.5 0.3 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FAM76 PF16046.5 ORY22534.1 - 6.9 5.9 10.7 0.17 11.2 0.2 2.5 2 0 0 2 2 2 0 FAM76 protein ZapB PF06005.12 ORY22535.1 - 0.0023 18.3 4.5 0.0072 16.7 1.4 2.5 2 0 0 2 2 2 1 Cell division protein ZapB Chorismate_synt PF01264.21 ORY22535.1 - 0.0024 16.7 0.0 0.0059 15.4 0.0 1.6 2 0 0 2 2 2 1 Chorismate synthase OrsD PF12013.8 ORY22535.1 - 0.0034 17.8 0.7 0.032 14.7 0.0 2.9 3 0 0 3 3 3 1 Orsellinic acid/F9775 biosynthesis cluster protein D Spc7 PF08317.11 ORY22535.1 - 0.023 13.6 1.3 0.047 12.6 1.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2508 PF10704.9 ORY22535.1 - 0.04 14.1 1.1 0.13 12.5 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) SlyX PF04102.12 ORY22535.1 - 0.081 13.6 9.0 4.1 8.1 3.5 2.7 2 0 0 2 2 2 0 SlyX CorA PF01544.18 ORY22535.1 - 0.19 11.0 1.1 0.29 10.4 1.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein GIT_CC PF16559.5 ORY22535.1 - 0.2 11.5 11.8 0.12 12.3 4.5 2.8 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cnn_1N PF07989.11 ORY22535.1 - 0.22 11.7 1.7 2.5 8.3 0.6 2.5 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 YabA PF06156.13 ORY22535.1 - 0.24 12.0 1.0 0.56 10.9 0.3 2.0 2 0 0 2 2 1 0 Initiation control protein YabA DivIC PF04977.15 ORY22535.1 - 0.39 10.5 5.5 0.13 12.0 2.0 1.9 2 0 0 2 2 2 0 Septum formation initiator JIP_LZII PF16471.5 ORY22535.1 - 0.47 10.7 3.4 0.19 11.9 0.3 2.0 2 0 0 2 2 1 0 JNK-interacting protein leucine zipper II Tropomyosin_1 PF12718.7 ORY22535.1 - 0.51 10.5 8.5 0.058 13.5 0.9 2.3 2 0 0 2 2 2 0 Tropomyosin like CDC45 PF02724.14 ORY22535.1 - 0.96 7.7 8.6 1.6 7.0 8.6 1.2 1 0 0 1 1 1 0 CDC45-like protein TMF_TATA_bd PF12325.8 ORY22535.1 - 2.3 8.5 8.1 1 9.6 4.1 2.4 2 1 0 2 2 1 0 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 ORY22535.1 - 7.2 7.1 8.1 0.33 11.5 2.4 1.7 2 0 0 2 2 1 0 Apg6 coiled-coil region Ribosomal_L27A PF00828.19 ORY22536.1 - 3.5e-25 89.1 1.3 4.1e-25 88.9 1.3 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF1242 PF06842.12 ORY22537.1 - 1.9e-16 59.5 0.3 2.6e-16 59.1 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) EF-hand_1 PF00036.32 ORY22538.1 - 1.8e-05 23.9 5.8 0.00025 20.4 1.6 3.2 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 ORY22538.1 - 7e-05 23.2 4.9 0.00087 19.7 2.5 2.9 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY22538.1 - 0.00013 21.6 6.2 0.018 14.9 1.1 4.0 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 ORY22538.1 - 0.0004 20.2 0.6 0.002 17.9 0.1 2.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 ORY22538.1 - 0.015 14.8 4.0 0.039 13.5 0.7 2.6 2 0 0 2 2 2 0 EF hand DUF592 PF04574.13 ORY22538.1 - 0.056 13.2 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF592) AdenylateSensor PF16579.5 ORY22538.1 - 0.063 13.7 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Adenylate sensor of SNF1-like protein kinase DEAD PF00270.29 ORY22539.1 - 6.2e-50 169.4 0.0 3e-49 167.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY22539.1 - 5.3e-16 59.0 0.0 1.4e-14 54.4 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY22539.1 - 2.3e-06 27.7 0.0 5.9e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RRM_1 PF00076.22 ORY22680.1 - 1.1e-14 54.0 0.0 1.5e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 7tm_2 PF00002.24 ORY22747.1 - 4.4e-13 49.1 0.7 8.7e-13 48.1 0.7 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 ORY22747.1 - 3.7e-08 33.0 1.3 4.6e-08 32.7 1.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 ORY22747.1 - 1.6e-06 28.0 7.4 2.4e-06 27.5 7.4 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 ORY22747.1 - 3.4e-05 23.1 4.8 3.4e-05 23.1 4.8 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor DUF2318 PF10080.9 ORY22748.1 - 0.00056 20.0 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2318) BTB PF00651.31 ORY22748.1 - 0.011 16.0 0.1 0.037 14.3 0.0 1.9 2 0 0 2 2 2 0 BTB/POZ domain BACK PF07707.15 ORY22748.1 - 0.037 14.1 0.1 0.067 13.3 0.1 1.4 1 0 0 1 1 1 0 BTB And C-terminal Kelch NB-ARC PF00931.22 ORY22748.1 - 0.045 12.9 0.0 0.078 12.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain BTB PF00651.31 ORY22749.1 - 5.3e-05 23.4 0.8 0.0002 21.6 0.4 2.0 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 ORY22749.1 - 0.032 14.3 0.2 0.054 13.6 0.2 1.3 1 0 0 1 1 1 0 BTB And C-terminal Kelch PBP_like_2 PF12849.7 ORY22775.1 - 9e-05 22.3 0.1 0.00011 22.0 0.1 1.1 1 0 0 1 1 1 1 PBP superfamily domain Flavodoxin_1 PF00258.25 ORY22776.1 - 0.04 14.1 0.0 0.073 13.3 0.0 1.5 1 1 0 1 1 1 0 Flavodoxin PAT1 PF09770.9 ORY22816.1 - 1.7 6.8 10.5 2.2 6.5 10.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 ORY22816.1 - 9.6 6.1 19.6 14 5.6 19.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TRAPPC9-Trs120 PF08626.11 ORY22817.1 - 5.8e-41 139.9 0.1 7.1e-41 139.6 0.1 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TRAPPC9-Trs120 PF08626.11 ORY22818.1 - 0.036 11.4 0.0 0.036 11.4 0.0 1.0 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TRAPPC9-Trs120 PF08626.11 ORY22819.1 - 7.2e-27 93.2 0.0 3.3e-19 67.8 0.0 2.1 2 0 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit SH3_9 PF14604.6 ORY22886.1 - 5.6e-12 45.3 0.1 1e-11 44.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY22886.1 - 6.3e-11 41.8 0.1 1.4e-10 40.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY22886.1 - 2.9e-09 36.4 3.1 1.2e-08 34.4 3.1 2.0 1 1 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 ORY22886.1 - 0.0015 18.7 0.3 0.0072 16.6 0.5 1.9 2 0 0 2 2 2 1 Bacterial SH3 domain SidE PF12252.8 ORY22886.1 - 0.027 12.0 1.6 0.033 11.7 1.6 1.0 1 0 0 1 1 1 0 Dot/Icm substrate protein DUF2730 PF10805.8 ORY22886.1 - 0.088 12.9 2.9 0.18 11.9 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) FliJ PF02050.16 ORY22886.1 - 0.97 9.7 6.3 1.1 9.5 2.3 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein FUSC PF04632.12 ORY22886.1 - 1.3 7.4 6.6 1.8 7.0 6.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1690 PF07956.11 ORY22886.1 - 2 8.8 7.2 0.94 9.9 2.7 2.2 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) FAM184 PF15665.5 ORY22886.1 - 2.2 8.0 8.8 2.2 8.0 2.5 2.3 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Jnk-SapK_ap_N PF09744.9 ORY22886.1 - 3.6 7.8 8.6 1.9 8.7 5.5 1.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 ORY22886.1 - 9.1 5.1 9.3 0.6 8.9 2.4 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Phage_lysis PF03245.13 ORY22886.1 - 10 6.3 10.7 0.48 10.6 3.8 2.2 2 1 1 3 3 3 0 Bacteriophage Rz lysis protein CFEM PF05730.11 ORY22888.1 - 0.032 14.3 0.3 0.17 12.0 0.2 1.9 2 0 0 2 2 2 0 CFEM domain Glyco_hydro_31 PF01055.26 ORY22890.1 - 2.1e-06 27.2 0.1 3.1e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 ABC_membrane PF00664.23 ORY22912.1 - 2.8e-06 27.2 2.4 3.6e-06 26.8 2.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region MWFE PF15879.5 ORY22912.1 - 0.29 11.3 5.8 0.26 11.5 0.9 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit ABC_tran PF00005.27 ORY22913.1 - 1.2e-32 113.3 2.5 3.6e-29 102.0 0.1 3.4 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 ORY22913.1 - 7.1e-16 58.7 6.8 3.6e-15 56.4 6.8 1.9 1 1 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ORY22913.1 - 3.8e-09 36.3 2.8 0.00037 20.0 0.0 3.4 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 ORY22913.1 - 0.001 19.2 0.5 0.0026 17.9 0.5 1.7 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_29 PF13555.6 ORY22913.1 - 0.0014 18.3 0.1 0.0037 17.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY22913.1 - 0.0029 17.7 0.1 0.012 15.7 0.1 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 ORY22913.1 - 0.0038 17.5 0.0 0.011 16.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY22913.1 - 0.0058 17.0 0.0 0.02 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 ORY22913.1 - 0.012 15.4 0.7 0.28 11.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 ORY22913.1 - 0.024 14.4 0.2 0.086 12.6 0.2 1.8 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 ORY22913.1 - 0.051 12.6 0.1 0.089 11.8 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.22 ORY22913.1 - 0.052 12.7 0.1 0.052 12.7 0.1 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 ORY22913.1 - 0.31 11.5 1.4 0.32 11.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain NadA PF02445.16 ORY22914.1 - 0.0021 17.3 1.6 0.0026 17.0 1.6 1.1 1 0 0 1 1 1 1 Quinolinate synthetase A protein Usp PF00582.26 ORY22914.1 - 0.0031 18.0 0.9 0.014 15.9 0.9 1.9 1 1 0 1 1 1 1 Universal stress protein family G3P_antiterm PF04309.12 ORY22914.1 - 0.023 14.1 0.1 0.033 13.6 0.1 1.2 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator DUF188 PF02639.14 ORY22914.1 - 0.053 13.2 0.9 0.076 12.7 0.9 1.3 1 0 0 1 1 1 0 Uncharacterized BCR, YaiI/YqxD family COG1671 HydF_dimer PF18128.1 ORY22914.1 - 0.094 12.8 0.4 4.9 7.3 0.4 2.3 1 1 0 1 1 1 0 Hydrogen maturase F dimerization domain PCMD PF13201.6 ORY22914.1 - 0.13 12.0 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 Putative carbohydrate metabolism domain DUF4939 PF16297.5 ORY22951.1 - 1.3e-05 25.1 0.1 1.3e-05 25.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4939) Retrotrans_gag PF03732.17 ORY22951.1 - 0.001 19.3 0.2 0.0014 18.9 0.2 1.2 1 0 0 1 1 1 1 Retrotransposon gag protein LRR_8 PF13855.6 ORY22952.1 - 8e-15 54.4 9.6 1.3e-08 34.5 0.9 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 ORY22952.1 - 3.3e-10 39.1 14.3 0.41 11.4 0.1 5.4 5 0 0 5 5 5 5 Leucine Rich Repeat LRR_4 PF12799.7 ORY22952.1 - 7.9e-09 35.7 16.8 8e-05 22.9 4.2 3.6 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY22952.1 - 0.016 15.3 12.2 4.9 7.5 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich repeat LRR_8 PF13855.6 ORY22953.1 - 7e-15 54.5 12.9 3.4e-08 33.1 5.1 4.6 2 1 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 ORY22953.1 - 1.5e-10 41.1 12.2 5e-06 26.8 0.2 5.3 3 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY22953.1 - 4.8e-06 26.4 13.0 0.21 12.2 0.0 7.1 6 2 1 7 7 7 2 Leucine Rich Repeat DUF3523 PF12037.8 ORY22990.1 - 0.032 13.6 5.1 0.26 10.6 3.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3523) DUF4637 PF15470.6 ORY22992.1 - 0.093 12.5 1.1 0.12 12.1 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) NDC10_II PF16787.5 ORY22993.1 - 5.8e-05 22.3 0.0 0.00011 21.4 0.0 1.5 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Cytochrom_B558a PF05038.13 ORY22993.1 - 1.4 8.5 3.0 2.7 7.5 3.0 1.4 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit PEX11 PF05648.14 ORY22995.1 - 4.3e-11 42.7 1.9 5.8e-05 22.7 0.2 2.0 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) CH PF00307.31 ORY22996.1 - 2.4e-17 63.1 0.2 4.7e-17 62.1 0.2 1.5 1 1 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 ORY22996.1 - 0.0086 16.3 0.1 0.013 15.7 0.1 1.3 1 0 0 1 1 1 1 CDC24 Calponin Calponin PF00402.18 ORY22996.1 - 0.07 12.8 1.0 0.14 11.8 0.1 2.0 3 0 0 3 3 3 0 Calponin family repeat DUF4899 PF16240.5 ORY22996.1 - 0.071 12.3 0.2 0.094 11.9 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4899) CdiI_2 PF18593.1 ORY22996.1 - 0.1 13.3 0.3 0.36 11.5 0.0 1.9 2 0 0 2 2 2 0 CdiI immunity protein Parathyroid PF01279.17 ORY22997.1 - 0.13 12.9 0.1 0.28 11.8 0.0 1.6 1 1 0 1 1 1 0 Parathyroid hormone family Autophagy_N PF03986.13 ORY22999.1 - 1e-43 148.6 0.0 2.3e-43 147.4 0.0 1.6 1 1 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 ORY22999.1 - 5.7e-19 68.5 0.7 1.3e-18 67.3 0.7 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 ORY22999.1 - 2.1e-14 52.7 1.6 2.1e-14 52.7 1.6 2.0 2 0 0 2 2 2 1 Autophagocytosis associated protein C-terminal zf-C4pol PF14260.6 ORY23077.1 - 4e-11 43.2 3.2 5.3e-11 42.8 3.2 1.2 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta NinF PF05810.12 ORY23077.1 - 0.02 14.8 0.5 0.02 14.8 0.5 1.6 2 0 0 2 2 2 0 NinF protein Arv1 PF04161.13 ORY23077.1 - 0.066 13.4 1.5 0.11 12.6 1.5 1.3 1 0 0 1 1 1 0 Arv1-like family DZR PF12773.7 ORY23077.1 - 0.24 11.5 7.4 3.8 7.6 7.5 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-ACC PF17848.1 ORY23077.1 - 0.31 11.2 0.1 0.31 11.2 0.1 2.6 2 1 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Fer4_2 PF12797.7 ORY23077.1 - 1.7 8.9 6.9 9.3 6.6 0.1 3.1 3 0 0 3 3 3 0 4Fe-4S binding domain RRM_1 PF00076.22 ORY23080.1 - 2.1e-14 53.1 0.0 2.3e-13 49.7 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4573 PF15140.6 ORY23080.1 - 2.1e-10 40.6 15.6 1.2e-05 25.1 9.2 3.6 1 1 2 3 3 3 3 Domain of unknown function (DUF4573) RRM_5 PF13893.6 ORY23080.1 - 0.058 13.0 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Amelogenin PF02948.15 ORY23080.1 - 9.9 6.8 14.4 5.8 7.5 8.3 3.3 3 2 0 4 4 4 0 Amelogenin DIMCO_N PF16844.5 ORY23087.1 - 0.054 13.8 0.1 1.6 9.1 0.0 2.1 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal CNH PF00780.22 ORY23180.1 - 6.4e-53 180.1 0.0 2.3e-52 178.3 0.0 1.8 2 0 0 2 2 2 1 CNH domain RhoGEF PF00621.20 ORY23180.1 - 9.5e-36 123.7 2.0 1.7e-35 122.9 2.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 ORY23180.1 - 5.3e-08 32.8 0.0 1.4e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_5 PF15405.6 ORY23180.1 - 2.6e-07 30.8 0.0 1.5e-05 25.2 0.0 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 ORY23180.1 - 0.0021 17.9 0.0 0.083 12.7 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH_16 PF17838.1 ORY23180.1 - 0.01 15.7 0.3 0.11 12.3 0.0 2.7 3 0 0 3 3 3 1 PH domain UvrD-helicase PF00580.21 ORY23180.1 - 0.044 13.3 0.1 0.082 12.4 0.1 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain PH PF00169.29 ORY23180.1 - 0.09 13.3 0.0 0.25 11.9 0.0 1.8 1 0 0 1 1 1 0 PH domain Cyclin_C PF02984.19 ORY23181.1 - 0.063 13.4 0.2 0.07 13.2 0.2 1.2 1 0 0 1 1 1 0 Cyclin, C-terminal domain DUF4055 PF13264.6 ORY23181.1 - 0.073 13.2 0.4 0.1 12.8 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4055) DNA_repr_REX1B PF14966.6 ORY23181.1 - 0.091 13.4 2.3 0.44 11.2 0.2 2.0 1 1 1 2 2 2 0 DNA repair REX1-B AIP3 PF03915.13 ORY23181.1 - 0.12 11.4 3.8 0.15 11.1 3.8 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 DUF948 PF06103.11 ORY23181.1 - 0.44 10.8 5.3 19 5.6 3.2 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 ORY23181.1 - 1.1 9.3 5.1 1.5 8.9 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) MFS_1 PF07690.16 ORY23182.1 - 2.2e-09 36.7 32.8 2.3e-09 36.6 20.8 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 ORY23183.1 - 2.1e-11 43.4 25.2 7.2e-10 38.3 19.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily CPSF_A PF03178.15 ORY23184.1 - 1.6e-26 93.4 0.0 4.5e-26 91.9 0.0 1.8 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 ORY23184.1 - 1.1e-23 83.6 0.0 5.9e-22 77.9 0.0 3.0 2 1 1 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term PQQ_3 PF13570.6 ORY23184.1 - 0.049 14.1 0.1 13 6.4 0.0 3.9 3 0 0 3 3 3 0 PQQ-like domain LRR_4 PF12799.7 ORY23185.1 - 5.9e-15 55.1 12.6 8.5e-05 22.8 0.5 4.6 1 1 6 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY23185.1 - 2.3e-14 52.9 12.4 0.00012 21.7 0.7 3.9 1 1 3 4 4 4 4 Leucine rich repeat F-box PF00646.33 ORY23185.1 - 5.2e-07 29.4 0.0 1.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.33 ORY23185.1 - 1.8e-06 27.7 18.7 3.7 8.5 0.2 7.3 6 1 0 6 6 6 4 Leucine Rich Repeat F-box-like PF12937.7 ORY23185.1 - 0.00015 21.6 0.0 0.00046 20.0 0.0 1.9 1 0 0 1 1 1 1 F-box-like NADH_u_ox_C PF12853.7 ORY23186.1 - 0.25 11.3 0.0 11 6.0 0.0 2.2 2 0 0 2 2 2 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit CoatB PF10389.9 ORY23186.1 - 0.82 9.6 6.8 2.5 8.0 6.8 1.9 1 0 0 1 1 1 0 Bacteriophage coat protein B dUTPase PF00692.19 ORY23187.1 - 0.028 14.1 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 dUTPase TMEM220 PF15071.6 ORY23188.1 - 1.1 10.1 4.5 2.5 8.9 0.4 2.8 3 0 0 3 3 3 0 Transmembrane family 220, helix Arm PF00514.23 ORY23189.1 - 7.8e-20 70.2 9.5 6e-09 35.6 0.0 5.6 5 1 1 6 6 6 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 ORY23189.1 - 7.8e-12 45.4 0.8 0.0097 16.3 0.1 4.0 2 1 0 3 3 3 3 HEAT repeats HEAT PF02985.22 ORY23189.1 - 1.7e-10 40.2 0.5 0.087 13.1 0.0 5.5 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 ORY23189.1 - 9.1e-09 35.6 8.0 0.0002 21.8 0.7 4.9 5 1 0 5 5 5 2 HEAT-like repeat DNA_alkylation PF08713.11 ORY23189.1 - 0.0002 21.2 0.0 1.4 8.6 0.0 3.3 3 1 0 3 3 3 2 DNA alkylation repair enzyme HEAT_PBS PF03130.16 ORY23189.1 - 0.0023 18.4 4.2 0.82 10.5 0.0 4.0 3 0 0 3 3 3 2 PBS lyase HEAT-like repeat Cnd1 PF12717.7 ORY23189.1 - 0.0096 16.0 0.0 13 5.7 0.0 3.1 2 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 TPR_12 PF13424.6 ORY23189.1 - 0.17 12.2 0.8 2.4 8.5 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY23189.1 - 1.4 9.2 3.1 49 4.4 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_12 PF13087.6 ORY23255.1 - 3.4e-06 26.8 0.0 4.4e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain DUF5384 PF17358.2 ORY23314.1 - 4 7.5 24.0 7 6.7 7.1 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5384) Ndc1_Nup PF09531.10 ORY23314.1 - 9.7 4.7 8.7 11 4.5 8.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DDE_Tnp_4 PF13359.6 ORY23315.1 - 2.5e-17 63.0 0.0 2e-10 40.5 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 ORY23315.1 - 0.013 15.1 0.0 0.52 9.9 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain DNA_methylase PF00145.17 ORY23316.1 - 4.9e-73 246.4 0.0 6.2e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase HSP90 PF00183.18 ORY23316.1 - 0.2 10.5 1.4 0.29 10.0 1.4 1.1 1 0 0 1 1 1 0 Hsp90 protein RCC1 PF00415.18 ORY23317.1 - 2.7e-75 248.8 12.1 4.5e-15 56.0 0.1 7.5 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY23317.1 - 2.7e-35 119.5 26.1 2.3e-07 30.4 0.3 7.7 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 ORY23317.1 - 0.034 14.6 0.2 39 4.7 0.0 4.0 4 0 0 4 4 4 0 SUKH-3 immunity protein PH PF00169.29 ORY23318.1 - 0.0019 18.7 0.1 0.0043 17.5 0.1 1.6 1 0 0 1 1 1 1 PH domain DUF3086 PF11285.8 ORY23318.1 - 0.19 10.8 5.1 0.11 11.6 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3086) BST2 PF16716.5 ORY23318.1 - 0.39 11.3 5.8 1.2 9.7 0.0 3.7 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 DUF1664 PF07889.12 ORY23318.1 - 1.4 9.0 9.8 7.2 6.7 0.6 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Nup54 PF13874.6 ORY23318.1 - 2.8 8.0 8.5 17 5.5 7.7 2.6 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 NPV_P10 PF05531.12 ORY23318.1 - 4 8.0 8.3 4.1 7.9 0.0 4.1 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein TMF_DNA_bd PF12329.8 ORY23318.1 - 4.4 7.4 11.0 0.61 10.1 4.9 2.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Spc24 PF08286.11 ORY23318.1 - 9.1 6.6 7.4 0.8 10.0 0.8 2.7 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Syja_N PF02383.18 ORY23319.1 - 9.2e-52 176.3 0.0 3.6e-51 174.4 0.0 1.8 1 1 1 2 2 2 1 SacI homology domain EF-hand_7 PF13499.6 ORY23320.1 - 5.8e-16 58.7 12.8 4.9e-11 42.9 1.6 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORY23320.1 - 2.7e-15 54.7 12.0 4.4e-06 25.9 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 ORY23320.1 - 1.2e-13 49.8 7.6 0.00019 21.1 0.1 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 ORY23320.1 - 3.7e-12 45.2 3.5 0.0031 17.0 0.1 3.9 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 ORY23320.1 - 3.4e-09 36.4 16.0 8.1e-06 25.6 3.1 4.2 3 2 0 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 ORY23320.1 - 0.0049 17.2 1.6 0.061 13.6 0.3 2.7 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 ORY23320.1 - 0.14 12.1 0.8 0.32 11.0 0.1 1.8 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF3636 PF12331.8 ORY23321.1 - 0.1 12.5 1.9 3.4 7.5 0.2 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3636) Med23 PF11573.8 ORY23321.1 - 0.18 9.4 0.4 0.32 8.6 0.1 1.4 2 0 0 2 2 2 0 Mediator complex subunit 23 SDA1 PF05285.12 ORY23321.1 - 3.9 6.8 7.3 6.6 6.1 7.3 1.3 1 0 0 1 1 1 0 SDA1 GTP_EFTU PF00009.27 ORY23323.1 - 3.4e-61 206.2 0.0 5.5e-61 205.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 ORY23323.1 - 5.1e-24 84.2 0.0 9.5e-24 83.3 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 ORY23323.1 - 1.5e-19 69.8 0.0 3.4e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 ORY23323.1 - 1.7e-09 37.5 0.0 6.7e-09 35.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 ORY23323.1 - 3.6e-08 33.7 0.0 1.6e-07 31.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 ORY23323.1 - 9.8e-05 22.2 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 ORY23323.1 - 0.00023 21.2 0.0 0.00045 20.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GST_N_2 PF13409.6 ORY23324.1 - 5.6e-24 84.2 0.0 9.1e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY23324.1 - 0.00014 22.2 0.0 0.0026 18.1 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY23324.1 - 0.0037 17.3 0.2 0.037 14.0 0.2 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Lactamase_B PF00753.27 ORY23325.1 - 3.2e-11 43.6 0.2 5.5e-10 39.6 0.2 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY23325.1 - 0.0022 17.5 0.1 0.0054 16.3 0.1 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain eIF2A PF08662.11 ORY23326.1 - 3.1e-48 164.2 0.5 2.2e-41 141.9 0.1 4.1 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 ORY23326.1 - 4.4e-11 42.4 0.1 1e-10 41.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 ORY23326.1 - 2.1e-05 25.2 3.3 3 8.8 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF4903 PF16246.5 ORY23326.1 - 0.018 14.7 0.1 0.037 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4903) p25-alpha PF05517.12 ORY23327.1 - 3.4e-12 46.8 0.9 4.1e-12 46.5 0.9 1.2 1 0 0 1 1 1 1 p25-alpha zf-MYND PF01753.18 ORY23328.1 - 1.9e-10 40.6 12.9 3.4e-10 39.8 12.9 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY23328.1 - 0.14 12.5 6.7 0.33 11.3 6.7 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-NADH-PPase PF09297.11 ORY23328.1 - 6.7 6.5 11.0 0.5 10.1 3.3 2.8 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Brr6_like_C_C PF10104.9 ORY23329.1 - 6.3e-39 132.8 0.1 8.6e-39 132.4 0.1 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Fig1 PF12351.8 ORY23329.1 - 0.1 12.5 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Sel1 PF08238.12 ORY23330.1 - 0.0096 16.6 0.9 12 6.8 0.0 3.7 3 0 0 3 3 3 2 Sel1 repeat TPR_2 PF07719.17 ORY23330.1 - 0.077 13.2 0.5 0.84 9.9 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPT PF03151.16 ORY23332.1 - 8.4e-24 84.4 24.5 1.2e-23 83.9 24.5 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family Bestrophin PF01062.21 ORY23334.1 - 1.8e-25 90.0 3.1 3.8e-16 59.4 0.3 2.7 2 1 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel CENP-T_C PF15511.6 ORY23335.1 - 2.1e-08 34.2 0.1 2.6e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 ORY23335.1 - 0.00045 20.6 0.2 0.00051 20.4 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORY23335.1 - 0.00053 20.3 0.0 0.00077 19.8 0.0 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 ORY23335.1 - 0.00096 19.3 0.1 0.0014 18.7 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 ORY23335.1 - 0.001 19.3 0.1 0.002 18.4 0.1 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY23335.1 - 0.028 14.5 0.0 0.032 14.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORY23335.1 - 0.16 12.0 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 ORY23335.1 - 0.18 12.3 0.0 0.35 11.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A VPS28 PF03997.12 ORY23336.1 - 6.7e-58 195.5 0.1 9.3e-58 195.0 0.1 1.2 1 0 0 1 1 1 1 VPS28 protein MiaE_2 PF13794.6 ORY23336.1 - 0.11 12.2 0.0 5.7 6.6 0.0 2.2 2 0 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Diphthami_syn_2 PF01902.17 ORY23337.1 - 4.8e-37 127.6 0.2 9.8e-37 126.6 0.2 1.4 1 1 0 1 1 1 1 Diphthamide synthase QueC PF06508.13 ORY23337.1 - 0.0024 17.4 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 ORY23337.1 - 0.059 12.2 0.0 0.085 11.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase Ribonuc_L-PSP PF01042.21 ORY23338.1 - 1.2e-08 34.9 0.0 0.00019 21.4 0.0 2.7 3 0 0 3 3 3 2 Endoribonuclease L-PSP Lep_receptor_Ig PF06328.11 ORY23338.1 - 0.09 12.7 0.5 2.4 8.2 0.0 3.0 2 1 0 2 2 2 0 Ig-like C2-type domain DUF2791 PF10923.8 ORY23338.1 - 0.23 10.3 0.0 0.3 9.9 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) ubiquitin PF00240.23 ORY23339.1 - 0.0012 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family KAR9 PF08580.10 ORY23339.1 - 1.3 7.5 8.8 1.7 7.1 8.8 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF719 PF05334.13 ORY23339.1 - 5.6 7.1 7.8 0.56 10.4 2.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Rap_GAP PF02145.15 ORY23340.1 - 2.4e-15 56.6 0.2 5.3e-14 52.2 0.0 2.5 2 0 0 2 2 2 1 Rap/ran-GAP PTH2 PF01981.16 ORY23341.1 - 1e-45 154.8 0.1 1.4e-45 154.3 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 FAM176 PF14851.6 ORY23341.1 - 0.041 13.5 0.2 0.063 12.9 0.2 1.3 1 0 0 1 1 1 0 FAM176 family Astro_capsid_p PF12226.8 ORY23341.1 - 0.094 11.9 7.0 0.14 11.3 7.0 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein TFIIF_alpha PF05793.12 ORY23341.1 - 0.097 11.2 5.9 0.13 10.9 5.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TRAP_alpha PF03896.16 ORY23341.1 - 0.15 11.2 0.6 0.18 11.0 0.6 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Serinc PF03348.15 ORY23341.1 - 0.19 10.6 0.1 0.26 10.2 0.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) CENP-B_dimeris PF09026.10 ORY23341.1 - 0.85 10.0 7.2 1.4 9.3 7.2 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Cwf_Cwc_15 PF04889.12 ORY23341.1 - 2 8.1 11.5 8.9 6.0 9.3 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 ORY23341.1 - 6.7 6.9 12.3 11 6.2 12.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BioY PF02632.14 ORY23342.1 - 0.036 14.1 4.2 0.051 13.6 4.2 1.3 1 0 0 1 1 1 0 BioY family DUF2534 PF10749.9 ORY23342.1 - 0.24 11.6 2.7 0.65 10.2 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2534) Glyco_trans_1_2 PF13524.6 ORY23343.1 - 4.5e-05 23.8 0.2 8.5e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 ABC2_membrane PF01061.24 ORY23344.1 - 7.5e-46 156.2 15.9 1.3e-45 155.4 15.9 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 ORY23344.1 - 5e-25 88.6 0.2 9.3e-25 87.7 0.2 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY23344.1 - 6.6e-06 26.2 0.2 0.067 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY23344.1 - 0.00018 21.0 0.1 0.00042 19.8 0.1 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 ORY23344.1 - 0.00022 20.4 14.8 0.00022 20.4 14.8 1.9 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC2_membrane_2 PF12679.7 ORY23344.1 - 0.0014 18.0 10.7 0.0038 16.6 10.5 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 ORY23344.1 - 0.0027 17.6 0.1 0.0051 16.7 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 ORY23344.1 - 0.018 15.5 0.0 0.031 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 ORY23344.1 - 0.02 14.8 0.3 0.047 13.6 0.3 1.6 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 ORY23344.1 - 0.024 14.2 0.1 0.044 13.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORY23344.1 - 0.057 13.1 0.2 0.092 12.5 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ORY23344.1 - 0.063 13.6 0.2 0.17 12.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain GTP_EFTU PF00009.27 ORY23345.1 - 8.9e-42 142.8 0.0 1.5e-41 142.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORY23345.1 - 5.6e-34 116.8 0.7 3.4e-33 114.3 0.1 2.6 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ORY23345.1 - 6.8e-12 45.6 0.1 1.4e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY23345.1 - 0.007 16.4 0.0 0.039 14.0 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 ORY23345.1 - 0.025 14.5 0.3 0.081 12.8 0.3 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 4 PAM2 PF07145.15 ORY23345.1 - 0.23 11.2 2.7 1.6 8.6 0.0 2.7 3 0 0 3 3 3 0 Ataxin-2 C-terminal region Methyltransf_25 PF13649.6 ORY23346.1 - 2.6e-10 40.8 0.0 4.5e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY23346.1 - 6.9e-06 26.7 0.0 1.4e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY23346.1 - 5.4e-05 23.8 0.0 0.00011 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY23346.1 - 0.061 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TehB PF03848.14 ORY23346.1 - 0.19 11.1 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB LRR_9 PF14580.6 ORY23448.1 - 0.0015 18.0 0.0 0.0016 18.0 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 ORY23448.1 - 0.03 14.1 0.3 0.052 13.3 0.2 1.6 1 1 0 1 1 1 0 Leucine rich repeat ADH_zinc_N_2 PF13602.6 ORY23450.1 - 2.3e-20 74.0 0.0 5.1e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY23450.1 - 1e-15 57.9 1.1 2.4e-15 56.7 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY23450.1 - 2.9e-05 23.9 0.4 0.00015 21.6 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 ORY23450.1 - 0.0072 16.1 0.8 0.0072 16.1 0.8 1.9 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF2855 PF11017.8 ORY23450.1 - 0.061 13.1 1.1 1.1 8.9 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2855) PGM_PMM_II PF02879.16 ORY23450.1 - 0.12 13.0 0.1 0.55 10.9 0.1 2.0 1 1 1 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DNA_methylase PF00145.17 ORY23451.1 - 6.9e-50 170.3 0.0 1.8e-24 86.7 0.0 2.1 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase CBM_6 PF03422.15 ORY23453.1 - 0.0077 16.5 2.2 0.14 12.4 0.7 2.4 2 0 0 2 2 2 2 Carbohydrate binding module (family 6) DDE_Tnp_4 PF13359.6 ORY23454.1 - 1.4e-17 63.8 0.0 9.8e-11 41.6 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 ORY23454.1 - 0.011 15.3 0.0 0.61 9.7 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain Mannosyl_trans3 PF11051.8 ORY23455.1 - 0.0072 15.7 0.0 0.01 15.2 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.8 ORY23456.1 - 1.1e-06 28.2 0.0 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative UDPGT PF00201.18 ORY23458.1 - 9.4e-24 84.1 0.0 2.6e-23 82.6 0.0 1.6 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 ORY23458.1 - 1.1e-07 32.0 0.0 2.3e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 ORY23458.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 ADH_zinc_N_2 PF13602.6 ORY23459.1 - 4e-20 73.2 0.0 1.2e-19 71.7 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY23459.1 - 4.9e-15 55.7 1.4 8.6e-15 54.9 0.2 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY23459.1 - 4.5e-09 36.2 1.9 1.3e-08 34.6 0.9 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Vps54 PF07928.12 ORY23459.1 - 0.01 16.3 1.8 4.9 7.6 0.1 2.9 2 1 1 3 3 3 2 Vps54-like protein ELFV_dehydrog PF00208.21 ORY23459.1 - 0.018 14.8 0.9 0.018 14.8 0.9 1.7 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SRI PF08236.11 ORY23459.1 - 0.033 14.4 0.2 17 5.7 0.0 2.8 2 1 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain DUF2855 PF11017.8 ORY23459.1 - 0.13 12.0 0.8 1.9 8.2 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2855) HTH_DeoR PF08220.12 ORY23459.1 - 0.2 11.4 0.4 30 4.4 0.1 2.6 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain ESP PF16590.5 ORY23462.1 - 3.9 7.8 6.9 0.45 10.8 0.6 2.4 2 0 0 2 2 2 0 Exocrine gland-secreting peptide USP8_dimer PF08969.11 ORY23463.1 - 0.022 15.0 1.0 0.041 14.1 1.0 1.5 1 0 0 1 1 1 0 USP8 dimerisation domain CDC37_C PF08564.10 ORY23463.1 - 0.034 14.3 0.6 0.047 13.8 0.6 1.3 1 0 0 1 1 1 0 Cdc37 C terminal domain MetRS-N PF09635.10 ORY23463.1 - 0.041 14.4 0.1 0.056 14.0 0.1 1.3 1 0 0 1 1 1 0 MetRS-N binding domain Folliculin PF11704.8 ORY23463.1 - 0.07 13.0 1.1 0.089 12.7 1.1 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Baculo_PEP_C PF04513.12 ORY23466.1 - 0.049 13.7 3.0 0.075 13.1 3.0 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HSBP1 PF06825.12 ORY23466.1 - 0.15 11.9 0.5 1.1 9.1 0.5 2.2 1 1 0 1 1 1 0 Heat shock factor binding protein 1 SKA1 PF07160.12 ORY23466.1 - 2.2 8.1 8.7 4.1 7.2 8.7 1.6 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 CHDCT2 PF08074.11 ORY23466.1 - 7.8 6.6 6.1 4.3 7.5 1.0 2.1 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain RCC1 PF00415.18 ORY23467.1 - 4.2e-75 248.2 12.3 6e-15 55.6 0.1 7.5 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY23467.1 - 2.7e-35 119.5 26.1 2.3e-07 30.4 0.3 7.8 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 ORY23467.1 - 0.035 14.6 0.3 39 4.7 0.0 4.0 4 0 0 4 4 4 0 SUKH-3 immunity protein PH PF00169.29 ORY23468.1 - 0.00084 19.8 0.0 0.002 18.6 0.0 1.7 1 0 0 1 1 1 1 PH domain DUF4760 PF15956.5 ORY23468.1 - 0.0059 16.7 0.1 0.012 15.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4760) DUF3450 PF11932.8 ORY23468.1 - 0.056 12.7 0.2 0.056 12.7 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF3086 PF11285.8 ORY23468.1 - 0.063 12.4 4.8 0.043 12.9 0.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3086) DivIC PF04977.15 ORY23468.1 - 0.24 11.2 2.3 0.78 9.6 2.3 1.9 1 0 0 1 1 1 0 Septum formation initiator Spc24 PF08286.11 ORY23468.1 - 0.37 11.1 4.8 0.13 12.5 0.4 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TMF_DNA_bd PF12329.8 ORY23468.1 - 0.44 10.6 10.2 0.091 12.8 4.9 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Nup54 PF13874.6 ORY23468.1 - 1.5 8.9 7.9 6.7 6.8 7.1 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 BST2 PF16716.5 ORY23468.1 - 3.1 8.5 0.0 3.1 8.5 0.0 3.9 4 0 0 4 4 4 0 Bone marrow stromal antigen 2 DUF3958 PF13125.6 ORY23468.1 - 3.1 8.0 10.5 0.26 11.5 4.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) DUF1664 PF07889.12 ORY23468.1 - 4 7.5 13.2 2.2 8.3 0.5 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.20 ORY23468.1 - 4.1 7.4 8.3 1.8 8.5 2.3 3.1 2 0 0 2 2 2 0 Prefoldin subunit NPV_P10 PF05531.12 ORY23468.1 - 8.2 7.0 9.6 22 5.6 3.0 4.2 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Syja_N PF02383.18 ORY23469.1 - 8.8e-52 176.4 0.0 3.1e-51 174.6 0.0 1.8 1 1 1 2 2 2 1 SacI homology domain EF-hand_7 PF13499.6 ORY23470.1 - 5.8e-16 58.7 12.8 4.9e-11 42.9 1.6 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORY23470.1 - 2.7e-15 54.7 12.0 4.4e-06 25.9 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 ORY23470.1 - 1.2e-13 49.8 7.6 0.00019 21.1 0.1 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 ORY23470.1 - 3.7e-12 45.2 3.5 0.0031 17.0 0.1 3.9 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 ORY23470.1 - 3.4e-09 36.4 16.0 8.1e-06 25.6 3.1 4.2 3 2 0 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 ORY23470.1 - 0.0049 17.2 1.6 0.061 13.6 0.3 2.7 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 ORY23470.1 - 0.14 12.1 0.8 0.32 11.0 0.1 1.8 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand GTP_EFTU PF00009.27 ORY23473.1 - 3.4e-61 206.2 0.0 5.5e-61 205.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 ORY23473.1 - 5.1e-24 84.2 0.0 9.5e-24 83.3 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 ORY23473.1 - 1.5e-19 69.8 0.0 3.4e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 ORY23473.1 - 2.6e-09 36.9 0.0 9.3e-09 35.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 ORY23473.1 - 3.5e-08 33.7 0.0 1.6e-07 31.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 ORY23473.1 - 0.00011 22.0 0.0 0.00022 21.1 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 ORY23473.1 - 0.00023 21.2 0.0 0.00045 20.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GST_N_2 PF13409.6 ORY23474.1 - 9e-25 86.8 0.3 3.7e-24 84.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY23474.1 - 1.3e-13 50.8 0.0 2.4e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY23474.1 - 5.6e-08 32.9 0.0 1.8e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY23474.1 - 6e-07 29.6 0.0 1.3e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORY23474.1 - 2.9e-05 24.4 0.0 0.00072 19.9 0.0 2.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Lactamase_B PF00753.27 ORY23475.1 - 7.5e-11 42.4 0.1 1.3e-09 38.4 0.1 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY23475.1 - 0.0044 16.6 0.1 0.0079 15.7 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain eIF2A PF08662.11 ORY23476.1 - 3.1e-48 164.3 0.5 2.2e-41 141.9 0.1 4.1 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 ORY23476.1 - 4.4e-11 42.4 0.1 1e-10 41.3 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 ORY23476.1 - 2.1e-05 25.2 3.3 3 8.8 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF4903 PF16246.5 ORY23476.1 - 0.017 14.8 0.1 0.035 13.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4903) zf-MYND PF01753.18 ORY23478.1 - 1.9e-10 40.7 12.9 3.5e-10 39.8 12.9 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY23478.1 - 0.12 12.7 6.7 0.34 11.2 6.7 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-NADH-PPase PF09297.11 ORY23478.1 - 7.2 6.4 11.0 0.52 10.0 3.3 2.8 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Brr6_like_C_C PF10104.9 ORY23479.1 - 1e-38 132.1 0.1 1.4e-38 131.7 0.1 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Neur_chan_memb PF02932.16 ORY23479.1 - 0.43 10.6 2.4 1.4 8.9 0.0 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Sel1 PF08238.12 ORY23480.1 - 0.00094 19.8 1.7 8.7 7.2 0.0 3.7 3 0 0 3 3 3 2 Sel1 repeat TPR_2 PF07719.17 ORY23480.1 - 0.041 14.0 1.0 0.54 10.5 0.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Arg_decarb_HB PF17810.1 ORY23480.1 - 0.097 12.9 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Arginine decarboxylase helical bundle domain TPR_8 PF13181.6 ORY23480.1 - 0.26 11.6 0.9 0.58 10.5 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY23480.1 - 3 8.6 7.5 0.45 11.2 1.8 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-CCCH PF00642.24 ORY23481.1 - 0.00011 22.0 0.2 0.00011 22.0 0.2 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 ORY23481.1 - 0.00032 20.4 2.5 0.00034 20.3 0.3 2.2 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ORY23481.1 - 0.00061 19.7 0.3 0.00061 19.7 0.3 2.1 2 1 0 2 2 2 1 Zinc finger domain zf-CCCH_2 PF14608.6 ORY23481.1 - 0.0015 18.9 1.2 0.0015 18.9 1.2 1.9 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 ORY23481.1 - 0.12 13.1 0.9 0.33 11.7 0.1 1.9 2 0 0 2 2 2 0 Torus domain DUF2457 PF10446.9 ORY23481.1 - 0.23 10.5 5.0 0.32 10.1 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) FAM176 PF14851.6 ORY23481.1 - 0.27 10.9 2.0 0.42 10.3 2.0 1.2 1 0 0 1 1 1 0 FAM176 family TPT PF03151.16 ORY23482.1 - 6.1e-18 65.2 10.9 7.5e-18 64.9 10.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family GH3 PF03321.13 ORY23565.1 - 1.5e-14 53.8 0.0 1.5e-09 37.3 0.0 2.1 1 1 1 2 2 2 2 GH3 auxin-responsive promoter BSP PF04450.12 ORY23754.1 - 3.2e-86 288.4 1.3 1.7e-44 152.1 0.0 3.0 3 0 0 3 3 3 3 Peptidase of plants and bacteria SprT-like PF10263.9 ORY23754.1 - 0.00014 21.7 1.2 0.098 12.5 0.2 3.2 3 0 0 3 3 3 2 SprT-like family DUF4157 PF13699.6 ORY23754.1 - 0.00036 20.7 2.1 0.5 10.6 0.1 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4157) Zincin_1 PF06262.11 ORY23754.1 - 0.036 14.2 2.8 0.9 9.7 0.3 2.7 2 0 0 2 2 2 0 Zincin-like metallopeptidase DUF3802 PF12290.8 ORY23754.1 - 0.036 14.6 0.1 0.14 12.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3802) SRP68 PF16969.5 ORY23754.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 RNA-binding signal recognition particle 68 Aspzincin_M35 PF14521.6 ORY23754.1 - 0.28 11.7 3.6 0.89 10.1 0.9 2.2 2 0 0 2 2 2 0 Lysine-specific metallo-endopeptidase Peptidase_M90 PF06167.12 ORY23754.1 - 0.5 9.9 3.8 4.2 6.9 0.0 2.9 3 0 0 3 3 3 0 Glucose-regulated metallo-peptidase M90 Pkinase_Tyr PF07714.17 ORY23755.1 - 2.5e-47 161.4 0.0 3.1e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORY23755.1 - 9e-38 130.1 0.0 1.1e-37 129.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 ORY23755.1 - 0.00078 18.8 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY23755.1 - 0.0012 18.8 0.0 0.0015 18.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY23755.1 - 0.071 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_4 PF02390.17 ORY23756.1 - 2.2e-22 79.4 0.0 5.6e-22 78.0 0.0 1.7 1 1 0 1 1 1 1 Putative methyltransferase zf-TRM13_CCCH PF11722.8 ORY23756.1 - 6.5e-06 25.8 2.5 1.3e-05 24.8 2.5 1.6 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein Methyltransf_12 PF08242.12 ORY23756.1 - 0.0041 17.8 0.0 0.023 15.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY23756.1 - 0.008 16.0 0.0 0.023 14.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY23756.1 - 0.012 15.5 0.0 0.026 14.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain 7tm_3 PF00003.22 ORY23757.1 - 6.1e-05 22.9 1.9 7.7e-05 22.5 1.9 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Fijivirus_P9-2 PF06837.11 ORY23757.1 - 0.0062 16.0 0.5 0.0077 15.7 0.5 1.1 1 0 0 1 1 1 1 Fijivirus P9-2 protein Herpes_UL37_2 PF07413.11 ORY23757.1 - 0.0064 15.8 0.5 0.0083 15.4 0.5 1.1 1 0 0 1 1 1 1 Betaherpesvirus immediate-early glycoprotein UL37 ATP-synt_Z PF16594.5 ORY23757.1 - 0.02 14.4 0.7 0.042 13.3 0.7 1.5 1 0 0 1 1 1 0 Putative AtpZ or ATP-synthase-associated Vpu PF00558.19 ORY23757.1 - 2.2 8.1 6.0 0.39 10.5 1.2 2.1 1 1 2 3 3 3 0 Vpu protein START PF01852.19 ORY23759.1 - 2.2e-11 43.6 0.0 3.7e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 START domain MFS_1 PF07690.16 ORY23761.1 - 1.1e-18 67.3 33.6 1.1e-18 67.3 33.6 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3611 PF12263.8 ORY23761.1 - 0.024 14.5 0.5 0.024 14.5 0.5 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF3611) DUF4094 PF13334.6 ORY23761.1 - 0.23 11.9 3.2 7.8 7.0 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) MFS_1 PF07690.16 ORY23762.1 - 4.4e-18 65.3 38.6 4.4e-18 65.3 38.6 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4094 PF13334.6 ORY23762.1 - 0.012 16.0 3.5 0.25 11.8 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) SnoaL_2 PF12680.7 ORY23763.1 - 7.6e-06 26.5 0.0 9.4e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ORY23763.1 - 0.025 14.4 0.0 0.038 13.8 0.0 1.3 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase TPR_19 PF14559.6 ORY23764.1 - 8.9e-06 26.1 0.0 5.5e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY23764.1 - 0.00014 22.4 0.0 0.11 13.4 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY23764.1 - 0.00019 21.6 0.1 0.005 17.1 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY23764.1 - 0.00096 18.8 0.1 0.44 10.3 0.0 2.5 2 1 1 3 3 3 2 TPR repeat Alkyl_sulf_dimr PF14863.6 ORY23764.1 - 0.0016 18.9 0.0 0.0059 17.1 0.0 1.8 2 0 0 2 2 2 1 Alkyl sulfatase dimerisation TPR_2 PF07719.17 ORY23764.1 - 0.0032 17.5 0.0 0.022 14.9 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY23764.1 - 0.0061 17.2 0.0 0.01 16.5 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY23764.1 - 0.012 15.5 0.0 0.086 12.7 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3446 PF11928.8 ORY23764.1 - 0.016 15.5 5.0 0.026 14.8 5.0 1.4 1 0 0 1 1 1 0 Early growth response N-terminal domain Sporozoite_P67 PF05642.11 ORY23764.1 - 8.2 4.4 7.3 11 4.0 7.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TPR_14 PF13428.6 ORY23765.1 - 1.6e-06 28.4 5.0 0.00034 21.2 0.5 4.8 1 1 4 5 5 5 1 Tetratricopeptide repeat DUF563 PF04577.14 ORY23765.1 - 2.2e-05 24.7 1.1 0.00017 21.8 1.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF563) TPR_2 PF07719.17 ORY23765.1 - 8.3e-05 22.4 3.5 3.1 8.2 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY23765.1 - 0.00021 21.7 2.9 0.078 13.5 0.1 3.3 2 1 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 ORY23765.1 - 0.0029 18.1 5.9 0.26 11.7 0.1 3.1 3 1 1 4 4 4 2 Bacterial transcriptional activator domain TPR_15 PF13429.6 ORY23765.1 - 0.0049 16.1 5.1 0.64 9.2 0.3 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY23765.1 - 0.0052 17.4 3.2 0.42 11.3 3.5 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat PPR_2 PF13041.6 ORY23765.1 - 0.0081 16.3 0.0 0.033 14.4 0.0 2.0 2 0 0 2 2 2 1 PPR repeat family TPR_6 PF13174.6 ORY23765.1 - 0.0087 16.6 0.1 59 4.6 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY23765.1 - 0.026 14.8 2.9 0.2 11.9 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY23765.1 - 0.028 14.6 1.4 0.18 12.1 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF885 PF05960.11 ORY23766.1 - 9.7e-114 381.9 0.1 1.1e-113 381.7 0.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) NOG1_N PF17835.1 ORY23766.1 - 0.12 12.3 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 NOG1 N-terminal helical domain DUF885 PF05960.11 ORY23767.1 - 4.3e-116 389.7 0.1 4.9e-116 389.5 0.1 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) NOG1_N PF17835.1 ORY23767.1 - 0.0063 16.5 0.0 0.12 12.4 0.0 2.5 2 0 0 2 2 2 1 NOG1 N-terminal helical domain AP_endonuc_2 PF01261.24 ORY23767.1 - 0.094 12.1 0.1 0.31 10.5 0.0 1.8 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel DUF563 PF04577.14 ORY23768.1 - 1.6e-21 77.4 0.0 2.5e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) TPR_14 PF13428.6 ORY23768.1 - 1.2e-09 38.1 1.6 0.085 13.7 0.3 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY23768.1 - 1.7e-09 38.0 4.0 0.043 14.3 0.1 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY23768.1 - 9.8e-07 29.3 3.4 0.0029 18.2 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY23768.1 - 2e-05 24.3 1.1 0.014 15.5 0.0 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat YfiO PF13525.6 ORY23768.1 - 2.9e-05 23.9 0.6 6.2e-05 22.8 0.2 1.6 2 0 0 2 2 2 1 Outer membrane lipoprotein TPR_11 PF13414.6 ORY23768.1 - 4.2e-05 23.2 2.3 0.00034 20.2 0.1 3.1 3 0 0 3 3 3 1 TPR repeat TPR_18 PF13512.6 ORY23768.1 - 0.0012 19.0 0.2 0.0032 17.6 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY23768.1 - 0.0079 16.5 1.0 3.5 8.0 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY23768.1 - 0.01 16.1 0.6 1.2 9.4 0.1 2.9 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 ORY23768.1 - 0.035 14.5 1.2 0.13 12.7 0.2 2.4 2 1 1 3 3 3 0 Bacterial transcriptional activator domain TPR_20 PF14561.6 ORY23768.1 - 0.074 13.4 3.8 28 5.1 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY23768.1 - 0.083 12.8 1.2 68 3.5 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 ORY23768.1 - 0.084 13.3 2.2 0.55 10.7 0.6 2.8 3 0 0 3 3 2 0 Alkyl sulfatase dimerisation TPR_4 PF07721.14 ORY23768.1 - 0.1 13.3 0.6 6.9 7.6 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.6 ORY23768.1 - 0.13 11.4 0.7 0.31 10.2 0.2 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY23768.1 - 1.3 9.8 3.8 0.52 11.1 0.4 2.3 3 0 0 3 3 1 0 Tetratricopeptide repeat DUF563 PF04577.14 ORY23769.1 - 2.4e-27 96.4 0.4 6.7e-27 95.0 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF563) TPR_2 PF07719.17 ORY23769.1 - 7.2e-12 44.5 0.0 0.0017 18.3 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 ORY23769.1 - 3e-09 36.9 0.1 0.37 11.5 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY23769.1 - 1e-07 31.5 0.0 0.00021 21.1 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY23769.1 - 1.4e-07 31.7 0.0 0.0072 16.6 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY23769.1 - 5e-07 30.0 0.1 0.73 10.8 0.0 4.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY23769.1 - 1e-06 29.2 0.0 0.0036 17.8 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY23769.1 - 6.5e-06 26.7 0.4 0.97 10.1 0.0 4.0 2 2 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY23769.1 - 5.1e-05 23.2 0.0 0.02 15.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY23769.1 - 0.00011 21.8 0.0 0.11 12.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY23769.1 - 0.00045 20.4 0.1 0.13 12.5 0.1 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 YfiO PF13525.6 ORY23769.1 - 0.0047 16.7 0.0 0.81 9.4 0.0 3.2 1 1 1 2 2 2 1 Outer membrane lipoprotein TPR_10 PF13374.6 ORY23769.1 - 0.14 12.1 0.1 3.1 7.8 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORY23769.1 - 0.14 12.6 0.1 1.8 9.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_18 PF13512.6 ORY23769.1 - 0.15 12.2 0.0 5.9 7.0 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF4133 PF13571.6 ORY23770.1 - 3.3 8.1 7.1 1.8 9.0 0.2 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4133) ubiquitin PF00240.23 ORY23772.1 - 1.2e-08 34.6 0.0 6.8e-08 32.1 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 ORY23772.1 - 9e-06 25.4 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PRIMA1 PF16101.5 ORY23772.1 - 0.031 14.3 8.9 0.084 12.9 8.9 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 zf-Di19 PF05605.12 ORY23772.1 - 0.21 11.9 1.0 20 5.6 0.1 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding KRTAP PF11759.8 ORY23772.1 - 1.1 9.9 18.7 2.3 8.8 18.7 1.5 1 0 0 1 1 1 0 Keratin-associated matrix DUF4200 PF13863.6 ORY23773.1 - 0.061 13.7 0.3 12 6.4 0.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) DUF4846 PF16138.5 ORY23773.1 - 0.17 11.4 0.1 0.26 10.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (4846) OrfB_Zn_ribbon PF07282.11 ORY23774.1 - 0.00036 20.4 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 Putative transposase DNA-binding domain MAPEG PF01124.18 ORY23776.1 - 9.7e-09 35.2 2.4 1.4e-08 34.7 2.4 1.3 1 1 0 1 1 1 1 MAPEG family TMEM70 PF06979.12 ORY23777.1 - 0.001 19.5 0.0 0.0017 18.8 0.0 1.3 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex TFIIA PF03153.13 ORY23778.1 - 0.063 13.3 4.3 0.093 12.7 4.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4600 PF15372.6 ORY23778.1 - 0.14 12.6 1.1 0.23 11.9 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) RasGAP_C PF03836.15 ORY23778.1 - 0.21 11.7 2.8 0.32 11.1 2.7 1.3 1 1 0 1 1 1 0 RasGAP C-terminus ADIP PF11559.8 ORY23778.1 - 0.41 10.7 6.7 0.54 10.3 6.7 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Cwf_Cwc_15 PF04889.12 ORY23778.1 - 0.52 10.0 5.5 0.76 9.5 5.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 ORY23778.1 - 2.4 7.4 6.8 3.3 6.9 6.8 1.2 1 0 0 1 1 1 0 NOA36 protein Ank_2 PF12796.7 ORY23779.1 - 1.4e-13 51.2 0.1 7e-09 36.2 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY23779.1 - 1.7e-12 47.6 0.0 1.8e-07 31.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY23779.1 - 2.9e-11 43.4 0.2 0.00046 20.4 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY23779.1 - 1.7e-08 34.0 0.5 0.0058 17.0 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 ORY23779.1 - 3.7e-08 33.5 2.9 0.064 13.7 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat OrfB_Zn_ribbon PF07282.11 ORY23780.1 - 0.006 16.5 0.0 0.006 16.5 0.0 2.2 2 0 0 2 2 2 1 Putative transposase DNA-binding domain WW PF00397.26 ORY23781.1 - 2.9e-09 36.9 5.0 2.9e-09 36.9 5.0 2.0 2 0 0 2 2 2 1 WW domain Cytotoxic PF09000.10 ORY23781.1 - 0.013 15.8 1.5 0.02 15.2 1.5 1.2 1 0 0 1 1 1 0 Cytotoxic SbcCD_C PF13558.6 ORY23781.1 - 0.5 10.6 4.0 0.18 12.1 0.6 1.9 1 1 1 2 2 2 0 Putative exonuclease SbcCD, C subunit CENP-B_dimeris PF09026.10 ORY23782.1 - 0.002 18.5 8.5 0.002 18.5 8.5 1.8 2 0 0 2 2 2 1 Centromere protein B dimerisation domain BUD22 PF09073.10 ORY23782.1 - 0.057 12.8 3.6 0.073 12.4 3.6 1.1 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.13 ORY23782.1 - 0.068 11.3 3.9 0.093 10.8 3.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi RXT2_N PF08595.11 ORY23782.1 - 0.089 12.8 0.8 0.13 12.3 0.3 1.6 2 0 0 2 2 2 0 RXT2-like, N-terminal Na_trans_assoc PF06512.13 ORY23782.1 - 0.12 12.6 0.9 0.18 12.1 0.9 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Nop14 PF04147.12 ORY23782.1 - 0.29 9.3 1.2 0.35 9.0 1.2 1.2 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 ORY23782.1 - 1.4 8.8 3.8 0.38 10.6 0.9 1.5 2 0 0 2 2 2 0 Sigma-70, non-essential region RNA_pol_3_Rpc31 PF11705.8 ORY23782.1 - 2.8 8.2 12.7 1.2 9.3 9.6 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 ORY23782.1 - 2.9 7.6 12.0 0.51 10.0 8.0 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 ORY23782.1 - 3.1 6.8 11.3 5.7 6.0 11.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF4611 PF15387.6 ORY23782.1 - 8.3 6.7 10.3 0.58 10.4 5.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) BSP PF04450.12 ORY23783.1 - 9.1e-06 25.6 0.0 9.2e-06 25.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase of plants and bacteria LRR_8 PF13855.6 ORY23784.1 - 1.5e-08 34.3 2.7 6.3e-05 22.7 0.3 2.7 2 1 2 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 ORY23784.1 - 6.8e-06 26.3 4.8 0.00023 21.5 0.5 2.9 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) PAN_1 PF00024.26 ORY23784.1 - 1.8e-05 24.6 0.1 1.8e-05 24.6 0.1 3.6 2 1 0 2 2 1 1 PAN domain LRR_6 PF13516.6 ORY23784.1 - 0.0015 18.4 4.8 0.42 10.8 0.2 3.2 3 0 0 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.33 ORY23784.1 - 0.018 15.5 0.0 20 6.2 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich Repeat Tmemb_cc2 PF10267.9 ORY23784.1 - 0.13 11.4 2.9 0.19 10.8 2.9 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SprA-related PF12118.8 ORY23784.1 - 0.42 9.7 20.8 0.74 8.9 20.8 1.4 1 0 0 1 1 1 0 SprA-related family Apt1 PF10351.9 ORY23784.1 - 0.89 8.3 8.1 1.2 7.9 8.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SpoIIIAH PF12685.7 ORY23784.1 - 1.4 8.7 13.7 2.1 8.1 13.7 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Macoilin PF09726.9 ORY23784.1 - 3.5 6.1 9.9 4.6 5.7 9.9 1.1 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 ORY23784.1 - 6.6 5.8 23.3 9.7 5.3 23.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein RAP1 PF07218.11 ORY23784.1 - 8.8 4.5 12.2 11 4.1 12.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SSB PF00436.25 ORY23785.1 - 3.1e-17 62.5 3.2 2.1e-12 47.0 0.4 2.2 1 1 1 2 2 2 2 Single-strand binding protein family Band_7 PF01145.25 ORY23786.1 - 3.2e-24 85.9 1.5 5.8e-24 85.1 1.1 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 ORY23786.1 - 0.0018 17.4 1.6 0.0023 17.1 1.6 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial DAGK_cat PF00781.24 ORY23786.1 - 0.0039 16.8 0.2 0.0093 15.6 0.2 1.6 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain Peptidase_S66 PF02016.15 ORY23786.1 - 0.046 13.8 0.1 0.086 13.0 0.1 1.4 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain ODAM PF15424.6 ORY23786.1 - 0.089 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Odontogenic ameloblast-associated family Band_7 PF01145.25 ORY23787.1 - 2.5e-24 86.2 1.2 5e-24 85.3 0.7 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 ORY23787.1 - 0.0019 17.4 1.7 0.0024 17.0 1.7 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial DAGK_cat PF00781.24 ORY23787.1 - 0.0038 16.8 0.2 0.0093 15.6 0.2 1.6 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain Peptidase_S66 PF02016.15 ORY23787.1 - 0.047 13.8 0.1 0.086 13.0 0.1 1.4 1 0 0 1 1 1 0 LD-carboxypeptidase N-terminal domain ODAM PF15424.6 ORY23787.1 - 0.091 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Odontogenic ameloblast-associated family Ribosomal_S8e PF01201.22 ORY23788.1 - 2.3e-56 189.7 2.5 2.7e-56 189.5 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e APG6_N PF17675.1 ORY23789.1 - 0.0067 17.0 0.4 0.02 15.4 0.3 1.8 2 0 0 2 2 2 1 Apg6 coiled-coil region Phage_GP20 PF06810.11 ORY23789.1 - 0.0091 15.8 4.5 0.0091 15.8 4.5 1.7 2 0 0 2 2 2 1 Phage minor structural protein GP20 Sec34 PF04136.15 ORY23789.1 - 0.0095 15.8 2.9 0.019 14.8 1.3 2.1 2 0 0 2 2 2 1 Sec34-like family TraF_2 PF13729.6 ORY23789.1 - 0.01 15.3 0.2 0.01 15.3 0.2 1.6 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein FapA PF03961.13 ORY23789.1 - 0.01 14.5 1.9 0.011 14.3 0.6 1.6 2 0 0 2 2 2 0 Flagellar Assembly Protein A NPV_P10 PF05531.12 ORY23789.1 - 0.013 15.9 5.1 0.057 13.9 1.5 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SKA2 PF16740.5 ORY23789.1 - 0.016 15.0 1.3 0.016 15.0 1.3 1.7 2 0 0 2 2 1 0 Spindle and kinetochore-associated protein 2 Rho_Binding PF08912.11 ORY23789.1 - 0.023 15.5 10.6 0.19 12.5 7.6 2.6 2 1 0 2 2 2 0 Rho Binding GrpE PF01025.19 ORY23789.1 - 0.039 13.6 4.9 0.017 14.8 2.7 1.5 2 0 0 2 2 1 0 GrpE LPD39 PF18858.1 ORY23789.1 - 0.047 13.8 0.7 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 Large polyvalent protein associated domain 39 NACHT_N PF17100.5 ORY23789.1 - 0.054 13.4 2.2 0.14 12.0 2.2 1.9 1 1 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase T3SSipB PF16535.5 ORY23789.1 - 0.054 14.0 3.4 3.8 8.0 0.3 2.2 2 0 0 2 2 2 0 Type III cell invasion protein SipB DUF148 PF02520.17 ORY23789.1 - 0.061 13.4 3.5 6.5 6.9 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function DUF148 Baculo_PEP_C PF04513.12 ORY23789.1 - 0.066 13.2 4.4 0.062 13.3 1.4 2.4 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med9 PF07544.13 ORY23789.1 - 0.098 12.8 2.5 1.5 9.0 1.8 2.4 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Ran-binding PF05508.11 ORY23789.1 - 0.12 11.3 4.5 0.78 8.7 4.5 2.1 1 1 0 1 1 1 0 RanGTP-binding protein Sec20 PF03908.13 ORY23789.1 - 0.17 11.8 2.1 0.83 9.6 0.9 2.5 1 1 2 3 3 3 0 Sec20 Fib_alpha PF08702.10 ORY23789.1 - 0.22 11.7 4.0 0.099 12.8 1.1 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family EzrA PF06160.12 ORY23789.1 - 0.26 9.4 8.8 0.094 10.9 6.2 1.5 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Med30 PF11315.8 ORY23789.1 - 0.26 11.5 3.2 1.9 8.7 0.1 2.3 1 1 1 2 2 2 0 Mediator complex subunit 30 Seryl_tRNA_N PF02403.22 ORY23789.1 - 0.49 10.6 10.2 0.26 11.5 6.2 2.3 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.12 ORY23789.1 - 1.1 9.3 5.0 8.8 6.4 1.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) KxDL PF10241.9 ORY23789.1 - 1.2 9.5 5.1 5 7.5 0.4 2.7 2 1 1 3 3 2 0 Uncharacterized conserved protein DUF948 PF06103.11 ORY23789.1 - 1.3 9.4 5.5 1.7 8.9 3.1 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4164 PF13747.6 ORY23789.1 - 1.3 9.4 5.6 9.1 6.6 4.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) NYD-SP28 PF14772.6 ORY23789.1 - 2.1 8.5 8.1 0.57 10.3 5.1 1.5 2 0 0 2 2 1 0 Sperm tail Bacillus_HBL PF05791.11 ORY23789.1 - 3.2 7.5 7.9 3.6 7.4 4.2 2.3 3 0 0 3 3 2 0 Bacillus haemolytic enterotoxin (HBL) EF-G-binding_N PF07299.11 ORY23789.1 - 8 7.1 9.4 0.73 10.4 2.6 2.5 2 1 0 3 3 2 0 Elongation factor G-binding protein, N-terminal YabA PF06156.13 ORY23789.1 - 8.8 7.0 6.9 0.96 10.1 1.5 2.2 3 1 0 3 3 1 0 Initiation control protein YabA Ank_2 PF12796.7 ORY23790.1 - 1.5e-60 201.8 14.1 4.6e-15 56.0 0.0 3.8 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY23790.1 - 3.1e-36 123.3 4.9 2.5e-10 40.7 0.0 5.4 2 1 4 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY23790.1 - 2e-26 91.7 0.5 4.2e-09 36.5 0.0 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY23790.1 - 6.8e-26 89.5 3.2 9e-07 29.1 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 ORY23790.1 - 1.6e-24 83.2 1.8 0.0001 22.4 0.0 6.0 7 0 0 7 7 7 5 Ankyrin repeat PEGA PF08308.11 ORY23790.1 - 0.034 14.1 0.0 13 5.8 0.0 3.7 3 1 1 4 4 4 0 PEGA domain ABC_membrane PF00664.23 ORY23879.1 - 9.9e-13 48.4 1.3 1.1e-12 48.2 1.3 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ORY23880.1 - 3.5e-29 102.1 0.0 4.8e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ORY23880.1 - 9.2e-07 28.5 0.1 0.0067 15.9 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ORY23880.1 - 0.0001 22.3 0.1 0.0073 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ORY23880.1 - 0.00096 19.4 0.0 0.014 15.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 ORY23880.1 - 0.0026 17.8 0.3 0.01 15.9 0.0 2.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY23880.1 - 0.0042 16.8 0.0 0.009 15.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 ORY23880.1 - 0.018 15.6 0.1 0.03 14.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ORY23880.1 - 0.022 13.9 0.1 0.041 13.1 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF87 PF01935.17 ORY23880.1 - 0.022 14.8 0.9 0.038 14.1 0.6 1.6 1 1 0 1 1 1 0 Helicase HerA, central domain AAA_30 PF13604.6 ORY23880.1 - 0.029 14.1 0.1 0.098 12.4 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 ORY23880.1 - 0.058 13.8 0.0 0.62 10.5 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 ORY23880.1 - 0.094 11.9 0.3 3.8 6.6 0.0 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain TniB PF05621.11 ORY23880.1 - 0.1 12.0 0.0 12 5.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein FKBP_N_2 PF18023.1 ORY23880.1 - 0.15 12.1 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 BDBT FKBP like N-terminal Zeta_toxin PF06414.12 ORY23880.1 - 0.22 10.8 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Ribosomal_S24e PF01282.19 ORY23882.1 - 0.069 13.1 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein S24e Exo_endo_phos_2 PF14529.6 ORY23883.1 - 0.0081 16.0 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Sua5_yciO_yrdC PF01300.18 ORY23884.1 - 0.13 11.7 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Telomere recombination DinB PF05163.12 ORY23885.1 - 3.4e-07 30.3 3.7 5.9e-07 29.6 3.7 1.7 1 1 0 1 1 1 1 DinB family DinB_2 PF12867.7 ORY23885.1 - 0.0012 19.3 0.0 0.0015 19.0 0.0 1.1 1 0 0 1 1 1 1 DinB superfamily DUF664 PF04978.12 ORY23885.1 - 0.099 13.1 0.1 0.12 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF664) Ysc84 PF04366.12 ORY23886.1 - 1.3e-38 131.7 0.2 1.7e-38 131.2 0.2 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator Glycos_transf_1 PF00534.20 ORY23886.1 - 0.029 13.9 0.0 0.052 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 Ysc84 PF04366.12 ORY23887.1 - 5.5e-37 126.4 0.3 7.5e-37 125.9 0.3 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator DUF2390 PF09523.10 ORY23888.1 - 0.089 13.1 0.0 0.26 11.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) VHS PF00790.19 ORY23892.1 - 4.6e-15 55.7 0.0 8e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 VHS domain Synuclein PF01387.17 ORY23892.1 - 0.06 13.6 0.4 0.11 12.7 0.4 1.3 1 0 0 1 1 1 0 Synuclein MFS_1 PF07690.16 ORY23893.1 - 4.7e-08 32.4 38.0 4.7e-08 32.4 38.0 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MG3 PF17791.1 ORY23893.1 - 0.12 12.7 0.2 0.32 11.3 0.2 1.7 1 0 0 1 1 1 0 Macroglobulin domain MG3 Peptidase_S8 PF00082.22 ORY23894.1 - 1.8e-50 171.9 4.5 3.4e-50 171.0 4.5 1.5 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 ORY23894.1 - 1.1e-11 45.4 1.4 1.1e-11 45.4 1.4 1.7 2 0 0 2 2 2 1 Fn3-like domain PA PF02225.22 ORY23894.1 - 4.4e-07 29.8 0.2 1.2e-06 28.4 0.2 1.8 1 0 0 1 1 1 1 PA domain FixG_C PF11614.8 ORY23894.1 - 0.023 14.9 0.2 0.051 13.8 0.2 1.5 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase PCI PF01399.27 ORY23896.1 - 1.8e-14 54.1 2.3 5.3e-14 52.6 0.0 2.8 3 1 0 3 3 3 1 PCI domain eIF3m_C_helix PF18005.1 ORY23896.1 - 4.1e-07 29.6 0.2 9.5e-07 28.4 0.2 1.7 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix Dynein_light PF01221.18 ORY23897.1 - 3.2e-23 81.9 0.3 3.8e-23 81.6 0.3 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Ysc84 PF04366.12 ORY23898.1 - 4.5e-34 117.0 0.8 6e-34 116.5 0.8 1.1 1 0 0 1 1 1 1 Las17-binding protein actin regulator EKR PF10371.9 ORY23898.1 - 0.05 13.4 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function Acetyltransf_7 PF13508.7 ORY23899.1 - 3e-06 27.6 0.0 4.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY23899.1 - 3.5e-06 27.0 0.0 5.7e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY23899.1 - 1.2e-05 25.5 0.0 1.7e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 ORY23899.1 - 0.00015 21.9 0.0 0.00023 21.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY23899.1 - 0.00057 20.0 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 ORY23899.1 - 0.0032 17.4 0.0 0.0064 16.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein TPR_12 PF13424.6 ORY23900.1 - 8.7e-07 29.1 4.8 0.037 14.3 0.3 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 ORY23900.1 - 0.00027 20.7 4.1 0.79 9.7 0.2 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.14 ORY23900.1 - 0.049 14.3 4.2 1.3 9.8 2.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY23900.1 - 0.19 12.0 0.8 45 4.6 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY23900.1 - 0.34 11.4 3.0 24 5.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY23900.1 - 1.2 10.1 3.1 64 4.8 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY23900.1 - 1.2 9.4 7.3 8.8 6.7 0.6 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat LBP_BPI_CETP PF01273.25 ORY23901.1 - 7e-11 42.0 0.5 0.0083 15.7 0.0 3.3 3 0 0 3 3 3 3 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP PF01273.25 ORY23902.1 - 1e-09 38.2 0.5 1.4e-09 37.7 0.5 1.2 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain DUF2218 PF09981.9 ORY23903.1 - 0.032 14.6 0.0 17 5.8 0.0 2.8 2 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2218) Myco_19_kDa PF05481.12 ORY23903.1 - 0.072 13.4 0.0 0.22 11.8 0.0 1.9 1 1 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen DNTTIP1_dimer PF18192.1 ORY23903.1 - 0.11 12.8 0.5 0.27 11.6 0.1 1.8 2 0 0 2 2 2 0 DNTTIP1 dimerisation domain zinc_ribbon_9 PF14369.6 ORY23904.1 - 7.6 6.9 19.8 3.3 8.1 0.1 6.2 6 0 0 6 6 6 0 zinc-ribbon cobW PF02492.19 ORY23905.1 - 3.1e-21 75.7 0.2 5.1e-21 75.0 0.2 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 ORY23905.1 - 0.00014 20.9 5.2 0.019 13.9 0.0 2.5 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 ORY23905.1 - 0.0014 18.2 1.2 0.05 13.1 0.0 2.7 2 1 0 2 2 1 1 Elongation factor Tu GTP binding domain AAA PF00004.29 ORY23905.1 - 0.0022 18.4 0.0 0.0022 18.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 ORY23905.1 - 0.005 17.4 1.5 0.013 16.0 0.1 2.3 3 0 0 3 3 2 1 AAA domain ABC_tran PF00005.27 ORY23905.1 - 0.0051 17.3 4.1 0.0054 17.3 0.2 2.4 2 1 1 3 3 3 1 ABC transporter AAA_23 PF13476.6 ORY23905.1 - 0.0073 16.8 2.6 0.015 15.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 ORY23905.1 - 0.008 16.1 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain TsaE PF02367.17 ORY23905.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 ORY23905.1 - 0.016 15.2 0.1 4.4 7.2 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 ORY23905.1 - 0.017 15.5 0.9 0.024 15.0 0.1 1.6 2 0 0 2 2 1 0 AAA ATPase domain AAA_5 PF07728.14 ORY23905.1 - 0.019 14.9 0.6 0.031 14.3 0.0 1.6 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 ORY23905.1 - 0.021 14.3 0.0 0.021 14.3 0.0 1.6 2 0 0 2 2 1 0 P-loop containing dynein motor region PRK PF00485.18 ORY23905.1 - 0.024 14.4 0.0 0.046 13.4 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF4175 PF13779.6 ORY23905.1 - 0.025 12.5 8.4 0.03 12.3 8.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) NTPase_1 PF03266.15 ORY23905.1 - 0.028 14.3 0.1 0.056 13.3 0.1 1.5 1 0 0 1 1 1 0 NTPase MMR_HSR1 PF01926.23 ORY23905.1 - 0.029 14.5 0.0 0.08 13.0 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 ORY23905.1 - 0.034 14.5 1.0 0.073 13.5 0.0 2.0 2 0 0 2 2 2 0 RNA helicase KAP_NTPase PF07693.14 ORY23905.1 - 0.044 13.0 0.6 0.16 11.1 0.0 1.9 2 1 0 2 2 2 0 KAP family P-loop domain CbiA PF01656.23 ORY23905.1 - 0.047 13.7 0.1 0.077 13.1 0.1 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain dNK PF01712.19 ORY23905.1 - 0.05 13.4 0.0 0.05 13.4 0.0 1.6 2 0 0 2 2 1 0 Deoxynucleoside kinase ATP_bind_1 PF03029.17 ORY23905.1 - 0.068 12.9 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein NACHT PF05729.12 ORY23905.1 - 0.078 12.9 0.0 0.078 12.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Flagellin_IN PF07196.13 ORY23905.1 - 0.087 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Flagellin hook IN motif AAA_29 PF13555.6 ORY23905.1 - 0.099 12.4 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 ORY23905.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein PqqD PF05402.12 ORY23905.1 - 0.12 12.7 0.0 12 6.3 0.0 2.3 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) T2SSE PF00437.20 ORY23905.1 - 0.13 11.3 1.0 0.39 9.7 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein MobB PF03205.14 ORY23905.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 ORY23905.1 - 0.18 11.0 0.0 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 ORY23905.1 - 0.21 11.8 0.0 0.21 11.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 ORY23905.1 - 0.24 11.6 3.0 0.49 10.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain TFIIA PF03153.13 ORY23905.1 - 1.3 9.0 13.9 1.8 8.5 13.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 ORY23905.1 - 2.9 7.4 13.6 4.3 6.9 13.6 1.2 1 0 0 1 1 1 0 Spt20 family SAP130_C PF16014.5 ORY23906.1 - 2.2 7.3 17.1 3.4 6.7 17.1 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus NFACT-R_1 PF05670.13 ORY23909.1 - 7.4e-20 71.6 0.1 3.4e-19 69.5 0.0 2.1 2 0 0 2 2 2 1 NFACT protein RNA binding domain NFACT-C PF11923.8 ORY23909.1 - 2e-15 56.6 0.1 2e-15 56.6 0.1 2.9 3 0 0 3 3 3 1 NFACT protein C-terminal domain TPR_10 PF13374.6 ORY23910.1 - 2.5e-88 287.9 12.6 1.6e-09 37.4 0.0 10.7 11 0 0 11 11 10 10 Tetratricopeptide repeat TPR_12 PF13424.6 ORY23910.1 - 5.6e-72 238.0 45.4 1.6e-15 57.1 0.7 7.3 4 2 4 8 8 8 8 Tetratricopeptide repeat TPR_2 PF07719.17 ORY23910.1 - 1.4e-51 168.5 61.5 1.9e-05 24.4 2.0 10.7 11 0 0 11 11 10 10 Tetratricopeptide repeat TPR_8 PF13181.6 ORY23910.1 - 4.3e-44 145.1 69.8 7.2e-05 22.7 1.5 11.4 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_7 PF13176.6 ORY23910.1 - 7.9e-42 138.2 29.3 0.00013 21.8 0.1 10.5 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_1 PF00515.28 ORY23910.1 - 1.7e-37 125.7 70.5 0.00033 20.4 0.1 10.6 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_14 PF13428.6 ORY23910.1 - 1.4e-33 112.7 8.7 0.012 16.4 0.0 10.5 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_6 PF13174.6 ORY23910.1 - 4.4e-19 67.8 40.2 0.19 12.4 0.3 10.9 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.6 ORY23910.1 - 4.8e-19 68.7 21.6 0.0074 16.9 1.7 10.0 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.6 ORY23910.1 - 5.5e-19 68.5 25.6 0.0033 17.9 0.5 7.2 4 3 2 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.6 ORY23910.1 - 6e-18 63.9 6.9 0.74 10.3 0.1 11.4 10 0 0 10 10 10 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY23910.1 - 2.1e-12 46.9 33.7 0.4 10.8 0.2 11.0 12 0 0 12 12 10 2 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 ORY23910.1 - 8.2e-11 41.5 11.8 5.3 8.0 0.1 9.5 10 0 0 10 10 9 0 Tetratricopeptide repeat TIR_2 PF13676.6 ORY23910.1 - 3.7e-09 37.2 0.0 9.7e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 TIR domain TPR_9 PF13371.6 ORY23910.1 - 7.7e-09 35.6 0.2 0.43 10.8 0.0 6.3 2 1 5 7 7 7 1 Tetratricopeptide repeat MIT PF04212.18 ORY23910.1 - 9.1e-08 32.1 51.8 0.49 10.5 0.0 10.4 4 2 6 10 10 10 3 MIT (microtubule interacting and transport) domain NUC173 PF08161.12 ORY23910.1 - 1.7e-07 31.1 2.2 0.98 9.0 0.0 5.4 3 1 3 7 7 7 2 NUC173 domain Glyoxalase PF00903.25 ORY23910.1 - 2.6e-06 27.6 0.2 55 4.0 0.0 7.1 8 2 1 10 10 6 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PPR PF01535.20 ORY23910.1 - 1.1e-05 25.3 10.0 11 6.5 0.1 9.0 9 0 0 9 9 9 0 PPR repeat ANAPC3 PF12895.7 ORY23910.1 - 1.9e-05 24.8 30.5 4.1 7.7 1.1 9.3 4 2 3 9 9 9 1 Anaphase-promoting complex, cyclosome, subunit 3 NB-ARC PF00931.22 ORY23910.1 - 3.9e-05 23.0 0.0 7.6e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.12 ORY23910.1 - 0.00039 20.4 0.0 0.001 19.0 0.0 1.7 2 0 0 2 2 1 1 NACHT domain Glyco_hydro_61 PF03443.14 ORY23910.1 - 0.0011 18.9 26.0 0.61 10.0 0.2 8.1 1 1 9 10 10 9 1 Glycosyl hydrolase family 61 RPN7 PF10602.9 ORY23910.1 - 0.0029 17.3 22.1 1.7 8.3 0.6 7.0 1 1 7 8 8 8 1 26S proteasome subunit RPN7 SHNi-TPR PF10516.9 ORY23910.1 - 0.0031 16.9 16.8 0.24 10.9 0.1 8.0 10 0 0 10 10 10 1 SHNi-TPR HTH_Tnp_Mu_2 PF09039.11 ORY23910.1 - 0.0037 17.3 2.6 69 3.6 0.0 5.9 4 3 3 7 7 7 0 Mu DNA binding, I gamma subdomain UPF0052 PF01933.18 ORY23910.1 - 0.0041 16.4 0.5 14 4.8 0.0 4.0 1 1 0 2 2 2 0 Uncharacterised protein family UPF0052 AAA_22 PF13401.6 ORY23910.1 - 0.0045 17.3 0.0 0.016 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain SPO22 PF08631.10 ORY23910.1 - 0.0077 15.8 14.0 0.37 10.2 0.3 5.0 3 2 2 5 5 5 3 Meiosis protein SPO22/ZIP4 like AAA_16 PF13191.6 ORY23910.1 - 0.015 15.7 0.0 0.046 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain TIR PF01582.20 ORY23910.1 - 0.045 13.6 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 TIR domain AAA PF00004.29 ORY23910.1 - 0.1 13.0 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 ORY23910.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF1657 PF07870.11 ORY23910.1 - 0.15 11.9 30.2 9.6 6.2 0.0 9.9 11 0 0 11 11 10 0 Protein of unknown function (DUF1657) Mob_Pre PF01076.19 ORY23910.1 - 3.3 7.5 17.5 45 3.8 0.3 6.9 8 2 0 8 8 6 0 Plasmid recombination enzyme DUF3450 PF11932.8 ORY23911.1 - 0.00077 18.8 1.2 0.001 18.4 1.0 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) Nsp1_C PF05064.13 ORY23911.1 - 0.00095 19.0 1.0 0.0011 18.8 1.0 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region ZapB PF06005.12 ORY23911.1 - 0.0011 19.4 4.4 0.0014 19.0 4.4 1.3 1 1 0 1 1 1 1 Cell division protein ZapB BLOC1_2 PF10046.9 ORY23911.1 - 0.0022 18.2 0.8 0.0029 17.9 0.8 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 ORY23911.1 - 0.0029 17.5 0.9 0.0033 17.3 0.9 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 BST2 PF16716.5 ORY23911.1 - 0.0042 17.6 2.2 0.0053 17.3 2.2 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 GAS PF13851.6 ORY23911.1 - 0.0057 16.0 2.8 0.0064 15.9 2.8 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding YabA PF06156.13 ORY23911.1 - 0.018 15.6 1.2 0.022 15.4 1.2 1.2 1 0 0 1 1 1 0 Initiation control protein YabA CCDC92 PF14916.6 ORY23911.1 - 0.019 14.7 3.5 0.034 13.9 3.3 1.6 1 1 0 1 1 1 0 Coiled-coil domain of unknown function Cluap1 PF10234.9 ORY23911.1 - 0.019 14.4 1.4 0.02 14.3 1.4 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Herpes_UL6 PF01763.16 ORY23911.1 - 0.019 13.5 1.5 0.02 13.5 1.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like HlyD_D23 PF16576.5 ORY23911.1 - 0.027 13.7 1.0 0.029 13.6 1.0 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion TMF_DNA_bd PF12329.8 ORY23911.1 - 0.034 14.1 1.1 0.034 14.1 1.1 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Rab_bind PF16704.5 ORY23911.1 - 0.034 14.2 0.3 2.8 8.1 0.1 2.3 1 1 1 2 2 2 0 Rab binding domain Sec34 PF04136.15 ORY23911.1 - 0.035 14.0 1.3 0.039 13.8 1.3 1.1 1 0 0 1 1 1 0 Sec34-like family APG6_N PF17675.1 ORY23911.1 - 0.046 14.3 2.7 0.062 13.8 2.7 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF948 PF06103.11 ORY23911.1 - 0.077 13.3 0.4 0.11 12.8 0.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 ORY23911.1 - 0.13 12.5 2.9 0.52 10.5 2.8 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 ORY23911.1 - 0.14 12.4 1.7 0.27 11.5 1.7 1.5 1 0 0 1 1 1 0 Haemolysin XhlA USP8_interact PF08941.10 ORY23911.1 - 0.15 11.9 1.9 0.18 11.6 1.9 1.1 1 0 0 1 1 1 0 USP8 interacting SlyX PF04102.12 ORY23911.1 - 0.27 11.9 4.6 2.1 9.0 4.6 2.1 1 1 0 1 1 1 0 SlyX DivIC PF04977.15 ORY23911.1 - 0.77 9.6 4.7 3.7 7.4 4.7 2.0 1 1 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 ORY23911.1 - 0.98 9.6 3.9 3.9 7.6 1.2 2.3 1 1 1 2 2 2 0 Basic region leucine zipper Neural_ProG_Cyt PF06567.11 ORY23913.1 - 7.8e-05 22.9 1.2 1.2 9.4 0.3 3.0 1 1 1 2 2 2 2 Neural chondroitin sulphate proteoglycan cytoplasmic domain MRP-S24 PF14955.6 ORY23913.1 - 0.0012 18.8 0.0 8.7 6.3 0.0 3.0 1 1 2 3 3 3 2 Mitochondrial ribosome subunit S24 ARTD15_N PF18084.1 ORY23913.1 - 0.0029 17.8 0.2 3.9 7.8 0.0 2.5 1 1 1 2 2 2 2 ARTD15 N-terminal domain Kisspeptin PF15152.6 ORY23913.1 - 0.031 15.1 3.0 1.3 9.8 0.1 3.0 1 1 2 3 3 3 0 Kisspeptin PAP2_3 PF14378.6 ORY23913.1 - 0.034 13.8 0.2 7.1 6.3 0.0 2.1 1 1 1 2 2 2 0 PAP2 superfamily Peptidase_C53 PF05550.11 ORY23913.1 - 0.058 13.1 0.1 63 3.2 0.0 3.0 3 0 0 3 3 3 0 Pestivirus Npro endopeptidase C53 Lantibiotic_a PF14867.6 ORY23913.1 - 0.066 13.0 0.0 79 3.1 0.0 3.1 3 0 0 3 3 3 0 Lantibiotic alpha DUF1798 PF08807.10 ORY23913.1 - 0.078 13.1 0.0 29 4.9 0.0 2.8 1 1 2 3 3 3 0 Bacterial domain of unknown function (DUF1798) HrpB7 PF09486.10 ORY23913.1 - 0.13 12.7 0.2 7.1 7.0 0.1 2.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Bravo_FIGEY PF13882.6 ORY23913.1 - 0.16 13.4 0.1 12 7.3 0.0 2.3 1 1 1 2 2 2 0 Bravo-like intracellular region DUF5315 PF17242.2 ORY23913.1 - 1.7 8.5 7.2 64 3.5 0.1 4.2 1 1 4 5 5 5 0 Disordered region of unknown function (DUF5315) GPP34 PF05719.11 ORY23915.1 - 0.081 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) FAD_binding_4 PF01565.23 ORY24028.1 - 5.4e-28 97.5 0.1 1.1e-27 96.5 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY24028.1 - 1.7e-05 24.8 0.0 4e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like SNAD3 PF18749.1 ORY24028.1 - 0.1 11.7 0.2 0.17 11.0 0.2 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 3 FAD_binding_4 PF01565.23 ORY24029.1 - 2.2e-28 98.7 0.2 3.7e-28 98.0 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain DASH_Dad2 PF08654.10 ORY24045.1 - 0.0063 16.9 1.9 0.05 14.0 0.5 2.8 1 1 1 2 2 2 1 DASH complex subunit Dad2 Phage_GPO PF05929.11 ORY24045.1 - 0.22 11.1 8.9 0.37 10.4 0.6 2.5 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase TSC22 PF01166.18 ORY24045.1 - 0.23 11.8 8.8 5.3 7.4 0.1 4.0 3 1 1 4 4 4 0 TSC-22/dip/bun family DUF724 PF05266.14 ORY24045.1 - 0.56 10.0 19.5 0.67 9.8 2.5 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.9 ORY24045.1 - 0.66 10.0 27.0 0.99 9.4 7.9 3.6 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4795 PF16043.5 ORY24045.1 - 0.7 9.5 15.2 2.9 7.4 14.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Jnk-SapK_ap_N PF09744.9 ORY24045.1 - 1.3 9.3 22.7 1.4 9.1 8.0 2.8 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 ORY24045.1 - 1.6 7.5 23.4 1.1 8.0 1.4 3.5 1 1 2 3 3 3 0 Spc7 kinetochore protein JIP_LZII PF16471.5 ORY24045.1 - 2.7 8.2 12.6 2.4 8.4 1.1 4.1 3 1 1 4 4 4 0 JNK-interacting protein leucine zipper II Snapin_Pallidin PF14712.6 ORY24045.1 - 6.4 7.3 17.7 1.8 9.1 1.8 3.9 2 1 1 3 3 3 0 Snapin/Pallidin YabA PF06156.13 ORY24045.1 - 8.5 7.1 12.8 7.4 7.3 2.5 3.4 2 2 0 2 2 2 0 Initiation control protein YabA Fungal_trans PF04082.18 ORY24137.1 - 0.0049 15.9 0.0 0.01 14.9 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zap1_zf2 PF18217.1 ORY24138.1 - 0.039 14.0 0.8 0.11 12.5 0.8 1.7 1 0 0 1 1 1 0 Zap1 zinc finger 2 F-box PF00646.33 ORY24139.1 - 7.2e-06 25.7 0.7 3.2e-05 23.7 0.1 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY24139.1 - 0.12 12.3 1.2 0.18 11.7 0.1 1.9 2 0 0 2 2 2 0 F-box-like LRR_4 PF12799.7 ORY24140.1 - 7.9e-09 35.7 11.6 0.00054 20.3 0.1 4.0 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY24140.1 - 0.00032 20.4 8.9 0.17 11.6 2.9 3.9 2 1 3 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 ORY24140.1 - 0.077 13.6 8.2 54 4.9 0.0 6.0 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 ORY24140.1 - 0.16 12.1 0.3 13 6.1 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich repeat BCDHK_Adom3 PF10436.9 ORY24141.1 - 0.069 13.0 0.2 2.6 7.9 0.1 2.3 2 1 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase OrfB_Zn_ribbon PF07282.11 ORY24233.1 - 0.006 16.5 0.0 0.006 16.5 0.0 2.4 2 0 0 2 2 2 1 Putative transposase DNA-binding domain TPR_2 PF07719.17 ORY24275.1 - 9.3e-06 25.4 0.9 0.14 12.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY24275.1 - 1.2e-05 24.9 0.1 0.41 10.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY24275.1 - 0.00043 19.7 0.4 0.0007 19.1 0.4 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_16 PF13432.6 ORY24275.1 - 0.00088 19.9 2.6 0.0028 18.3 0.2 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY24275.1 - 0.0028 17.9 0.1 0.02 15.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY24275.1 - 0.0049 17.4 0.0 0.023 15.2 0.0 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY24275.1 - 0.015 15.5 2.2 26 5.3 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY24275.1 - 0.026 14.8 3.3 0.092 13.1 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 ORY24275.1 - 0.11 12.6 1.3 11 6.3 0.2 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat Dict-STAT-coil PF09267.10 ORY24275.1 - 0.24 11.8 2.1 0.55 10.6 0.0 2.5 3 0 0 3 3 3 0 Dictyostelium STAT, coiled coil TPR_10 PF13374.6 ORY24275.1 - 0.64 10.0 4.9 0.34 10.8 0.8 2.6 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY24275.1 - 0.7 10.9 3.7 75 4.6 0.0 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat CENP-Q PF13094.6 ORY24276.1 - 0.052 13.8 0.6 0.052 13.8 0.6 2.2 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit MT PF12777.7 ORY24276.1 - 0.51 9.3 5.7 0.55 9.2 5.7 1.1 1 0 0 1 1 1 0 Microtubule-binding stalk of dynein motor LRR_1 PF00560.33 ORY24277.1 - 0.011 16.1 4.4 17 6.4 0.1 4.7 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 ORY24277.1 - 0.029 14.4 11.8 0.46 10.7 1.2 4.0 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 ORY24277.1 - 0.068 13.6 16.3 0.85 10.1 1.6 4.4 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY24277.1 - 0.3 10.9 10.4 2.1 8.2 0.5 4.0 3 0 0 3 3 3 0 Leucine rich repeat DDE_Tnp_4 PF13359.6 ORY24279.1 - 2.5e-10 40.2 0.0 3.6e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Sars6 PF12133.8 ORY24280.1 - 0.11 12.5 0.1 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 Open reading frame 6 from SARS coronavirus V-SNARE_C PF12352.8 ORY24361.1 - 0.013 15.8 1.5 39 4.6 0.0 4.0 3 1 1 4 4 4 0 Snare region anchored in the vesicle membrane C-terminus TIG PF01833.24 ORY24361.1 - 0.032 14.3 5.8 1.3 9.2 0.7 2.3 1 1 1 2 2 2 0 IPT/TIG domain RRG8 PF17068.5 ORY24361.1 - 3 7.2 4.8 8 5.8 0.7 2.0 1 1 1 2 2 2 0 Required for respiratory growth protein 8 mitochondrial X PF00739.19 ORY24361.1 - 5.4 7.1 10.2 12 6.0 1.9 2.3 1 1 1 2 2 2 0 Trans-activation protein X DUF3450 PF11932.8 ORY24362.1 - 0.00077 18.8 1.2 0.001 18.4 1.0 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) Nsp1_C PF05064.13 ORY24362.1 - 0.00095 19.0 1.0 0.0011 18.8 1.0 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region ZapB PF06005.12 ORY24362.1 - 0.0011 19.4 4.4 0.0014 19.0 4.4 1.3 1 1 0 1 1 1 1 Cell division protein ZapB BLOC1_2 PF10046.9 ORY24362.1 - 0.0022 18.2 0.8 0.0029 17.9 0.8 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 ORY24362.1 - 0.0029 17.5 0.9 0.0033 17.3 0.9 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 BST2 PF16716.5 ORY24362.1 - 0.0042 17.6 2.2 0.0053 17.3 2.2 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 GAS PF13851.6 ORY24362.1 - 0.0057 16.0 2.8 0.0064 15.9 2.8 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding YabA PF06156.13 ORY24362.1 - 0.018 15.6 1.2 0.022 15.4 1.2 1.2 1 0 0 1 1 1 0 Initiation control protein YabA CCDC92 PF14916.6 ORY24362.1 - 0.019 14.7 3.5 0.034 13.9 3.3 1.6 1 1 0 1 1 1 0 Coiled-coil domain of unknown function Cluap1 PF10234.9 ORY24362.1 - 0.019 14.4 1.4 0.02 14.3 1.4 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Herpes_UL6 PF01763.16 ORY24362.1 - 0.019 13.5 1.5 0.02 13.5 1.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like HlyD_D23 PF16576.5 ORY24362.1 - 0.027 13.7 1.0 0.029 13.6 1.0 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion TMF_DNA_bd PF12329.8 ORY24362.1 - 0.034 14.1 1.1 0.034 14.1 1.1 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Rab_bind PF16704.5 ORY24362.1 - 0.034 14.2 0.3 2.8 8.1 0.1 2.3 1 1 1 2 2 2 0 Rab binding domain Sec34 PF04136.15 ORY24362.1 - 0.035 14.0 1.3 0.039 13.8 1.3 1.1 1 0 0 1 1 1 0 Sec34-like family APG6_N PF17675.1 ORY24362.1 - 0.046 14.3 2.7 0.062 13.8 2.7 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF948 PF06103.11 ORY24362.1 - 0.077 13.3 0.4 0.11 12.8 0.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 ORY24362.1 - 0.13 12.5 2.9 0.52 10.5 2.8 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 ORY24362.1 - 0.14 12.4 1.7 0.27 11.5 1.7 1.5 1 0 0 1 1 1 0 Haemolysin XhlA USP8_interact PF08941.10 ORY24362.1 - 0.15 11.9 1.9 0.18 11.6 1.9 1.1 1 0 0 1 1 1 0 USP8 interacting SlyX PF04102.12 ORY24362.1 - 0.27 11.9 4.6 2.1 9.0 4.6 2.1 1 1 0 1 1 1 0 SlyX DivIC PF04977.15 ORY24362.1 - 0.77 9.6 4.7 3.7 7.4 4.7 2.0 1 1 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 ORY24362.1 - 0.98 9.6 3.9 3.9 7.6 1.2 2.3 1 1 1 2 2 2 0 Basic region leucine zipper DUF1943 PF09172.11 ORY24365.1 - 0.0065 15.7 0.7 0.0081 15.4 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) ABC_tran PF00005.27 ORY24436.1 - 3.1e-17 63.4 0.1 4.9e-16 59.5 0.0 2.6 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 ORY24436.1 - 3.8e-15 56.5 0.0 8.2e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 ORY24436.1 - 3.1e-05 23.3 10.3 3.1e-05 23.3 10.3 1.9 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_23 PF13476.6 ORY24436.1 - 0.005 17.4 0.1 0.012 16.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 ORY24436.1 - 0.0052 16.5 1.2 0.33 10.6 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain SMC_N PF02463.19 ORY24436.1 - 0.0089 15.5 0.0 0.84 9.0 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 ORY24436.1 - 0.017 14.8 0.0 0.094 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 ORY24436.1 - 0.11 11.1 0.1 2.3 6.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ORY24436.1 - 0.13 12.0 0.8 0.31 10.8 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Gti1_Pac2 PF09729.9 ORY24437.1 - 1e-24 87.6 0.1 1.6e-20 74.0 0.0 2.6 2 1 1 3 3 3 2 Gti1/Pac2 family TrmO_C PF18389.1 ORY24437.1 - 0.57 10.3 3.9 0.56 10.4 2.2 1.8 2 0 0 2 2 2 0 TrmO C-terminal domain BUD22 PF09073.10 ORY24438.1 - 0.013 14.9 11.8 0.014 14.8 11.8 1.1 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 ORY24438.1 - 0.014 14.2 4.0 0.018 13.9 4.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CNDH2_C PF16858.5 ORY24438.1 - 0.026 14.4 6.1 0.029 14.3 6.1 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SDA1 PF05285.12 ORY24438.1 - 0.033 13.6 17.8 0.041 13.3 17.8 1.1 1 0 0 1 1 1 0 SDA1 CFEM PF05730.11 ORY24438.1 - 0.073 13.2 2.4 0.14 12.3 2.4 1.5 1 0 0 1 1 1 0 CFEM domain Mpp10 PF04006.12 ORY24438.1 - 0.1 11.0 13.7 0.13 10.7 13.7 1.1 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 ORY24438.1 - 0.11 10.7 18.7 0.13 10.5 18.7 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 ORY24438.1 - 0.24 9.4 23.9 0.31 9.1 23.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2722 PF10846.8 ORY24438.1 - 0.25 10.2 7.9 0.27 10.1 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) PPP4R2 PF09184.11 ORY24438.1 - 0.26 10.9 14.8 0.31 10.6 14.8 1.1 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.14 ORY24438.1 - 0.65 8.2 14.0 0.78 8.0 14.0 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 ORY24438.1 - 0.83 8.9 23.1 0.98 8.7 22.6 1.3 1 1 0 1 1 1 0 NOA36 protein RR_TM4-6 PF06459.12 ORY24438.1 - 1.2 9.0 7.0 1.4 8.7 7.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRN3 PF05327.11 ORY24438.1 - 1.2 7.6 14.5 1.5 7.3 14.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CobT PF06213.12 ORY24438.1 - 2.5 7.4 18.8 3.3 7.0 18.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF913 PF06025.12 ORY24438.1 - 2.8 6.8 6.1 3.7 6.4 6.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Paf1 PF03985.13 ORY24438.1 - 2.8 6.8 13.8 3.8 6.4 13.8 1.1 1 0 0 1 1 1 0 Paf1 Vfa1 PF08432.10 ORY24438.1 - 3.4 7.9 10.2 5.2 7.4 10.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4746 PF15928.5 ORY24438.1 - 4.5 6.6 9.9 6.3 6.1 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) eIF-3c_N PF05470.12 ORY24438.1 - 6.3 5.0 10.0 9 4.5 10.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Pes-10 PF07149.11 ORY24438.1 - 9.9 5.1 15.8 13 4.7 15.8 1.1 1 0 0 1 1 1 0 Pes-10 Galactosyl_T PF01762.21 ORY24439.1 - 0.0089 15.9 0.0 0.84 9.4 0.0 2.6 1 1 1 2 2 2 2 Galactosyltransferase Fringe PF02434.16 ORY24439.1 - 0.049 13.0 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 Fringe-like Pkinase PF00069.25 ORY24440.1 - 2.7e-61 207.2 0.0 4.4e-61 206.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY24440.1 - 3.8e-30 105.0 0.0 6.6e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 ORY24440.1 - 6.5e-15 55.0 7.1 1.9e-09 37.5 0.3 4.0 3 1 0 3 3 3 2 Hr1 repeat C1_1 PF00130.22 ORY24440.1 - 2.9e-13 49.5 19.1 5.5e-07 29.4 7.4 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 ORY24440.1 - 1.3e-09 38.6 0.4 4.6e-09 36.8 0.4 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 ORY24440.1 - 0.0002 20.4 0.1 0.00054 19.0 0.1 1.7 1 0 0 1 1 1 1 Haspin like kinase domain Fer4_9 PF13187.6 ORY24440.1 - 0.33 11.1 13.2 1.1 9.4 11.9 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain PHD PF00628.29 ORY24440.1 - 0.8 9.7 18.6 0.87 9.5 3.5 2.7 2 0 0 2 2 2 0 PHD-finger Presenilin PF01080.17 ORY24440.1 - 1.2 7.9 4.3 2.5 6.8 4.3 1.4 1 0 0 1 1 1 0 Presenilin DUF1501 PF07394.12 ORY24440.1 - 7.8 5.4 8.8 18 4.3 8.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Peptidase_M50 PF02163.22 ORY24536.1 - 0.12 11.6 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M50 DUF2892 PF11127.8 ORY24537.1 - 0.1 12.7 0.6 0.1 12.7 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2892) Acyltransferase PF01553.21 ORY24538.1 - 6.8e-18 64.6 1.4 3.6e-17 62.2 0.0 2.2 2 0 0 2 2 2 1 Acyltransferase Acyltransf_C PF16076.5 ORY24538.1 - 3.4e-05 23.9 2.9 0.00038 20.5 2.9 2.2 1 1 0 1 1 1 1 Acyltransferase C-terminus ThrE PF06738.12 ORY24538.1 - 0.11 11.8 0.7 0.17 11.2 0.7 1.3 1 0 0 1 1 1 0 Putative threonine/serine exporter PRiA4_ORF3 PF07929.11 ORY24538.1 - 0.14 11.8 0.2 0.23 11.2 0.2 1.2 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein Pkinase PF00069.25 ORY24539.1 - 1.8e-75 253.7 0.0 2.6e-75 253.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY24539.1 - 1.4e-37 129.4 0.0 2.1e-37 128.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY24539.1 - 2.1e-06 26.9 0.3 4.7e-06 25.8 0.3 1.5 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY24539.1 - 1.3e-05 25.3 0.2 0.0028 17.6 0.2 2.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY24539.1 - 3.6e-05 23.2 0.2 6.3e-05 22.4 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORY24539.1 - 5.1e-05 22.9 0.2 9.7e-05 22.0 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 ORY24539.1 - 0.00012 21.5 0.0 0.00026 20.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 ORY24539.1 - 0.00074 18.7 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 YukC PF10140.9 ORY24539.1 - 0.007 15.2 0.4 0.01 14.7 0.4 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC YrbL-PhoP_reg PF10707.9 ORY24539.1 - 0.028 13.9 0.1 0.056 13.0 0.1 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.20 ORY24539.1 - 0.052 13.1 0.1 0.13 11.8 0.1 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase DSBA PF01323.20 ORY24540.1 - 2.3e-47 161.3 0.0 1e-25 90.7 0.0 2.1 2 0 0 2 2 2 2 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 ORY24540.1 - 0.18 12.0 0.0 5.9 7.0 0.0 2.3 2 1 0 2 2 2 0 Thioredoxin NOP5NT PF08156.13 ORY24541.1 - 0.11 12.9 0.9 9 6.8 0.1 2.6 2 1 0 2 2 2 0 NOP5NT (NUC127) domain PIF1 PF05970.14 ORY24542.1 - 1.9e-11 43.7 0.1 2.6e-11 43.3 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase SH3_13 PF18335.1 ORY24542.1 - 1.9e-05 24.4 0.0 3.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain Hydrophobin PF01185.18 ORY24542.1 - 0.019 15.6 0.5 0.03 15.0 0.5 1.2 1 0 0 1 1 1 0 Fungal hydrophobin LANC_like PF05147.13 ORY24542.1 - 0.046 12.3 0.0 0.057 12.0 0.0 1.1 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein Mg_trans_NIPA PF05653.14 ORY24544.1 - 5.3e-07 29.0 20.2 0.0012 18.0 3.7 2.3 2 0 0 2 2 2 2 Magnesium transporter NIPA DUF2087 PF09860.9 ORY24545.1 - 4.8e-08 33.0 0.0 1.1e-07 31.9 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2087) HTH_1 PF00126.27 ORY24545.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family zf-C2H2 PF00096.26 ORY24546.1 - 8.4e-10 38.6 19.1 9.2e-05 22.7 0.5 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY24546.1 - 3.7e-09 36.6 21.4 4.6e-05 23.6 4.0 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY24546.1 - 6.3e-07 29.7 18.1 0.009 16.8 0.5 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORY24546.1 - 0.011 15.9 7.2 0.12 12.5 0.1 2.3 1 1 1 2 2 2 0 Aberrant zinc-finger Lact-deh-memb PF09330.11 ORY24546.1 - 0.028 13.8 0.0 0.039 13.3 0.0 1.3 1 1 0 1 1 1 0 D-lactate dehydrogenase, membrane binding Zn-C2H2_12 PF18112.1 ORY24546.1 - 0.029 14.8 6.7 3 8.4 0.7 3.3 3 1 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain TRAF6_Z2 PF18048.1 ORY24546.1 - 0.051 13.7 11.7 0.078 13.1 0.7 3.5 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 FOXP-CC PF16159.5 ORY24546.1 - 0.34 11.6 6.6 15 6.3 3.3 2.9 2 1 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_9 PF16293.5 ORY24546.1 - 0.38 10.6 6.5 3.4 7.6 1.1 2.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2H2_6 PF13912.6 ORY24546.1 - 1.5 8.9 13.8 9.2 6.4 0.3 3.7 3 2 0 3 3 3 0 C2H2-type zinc finger PACT_coil_coil PF10495.9 ORY24547.1 - 3.5e-06 27.5 5.8 0.00015 22.3 0.0 4.7 4 0 0 4 4 4 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein ATG16 PF08614.11 ORY24547.1 - 5.4e-06 26.8 132.9 0.021 15.0 10.0 9.0 2 1 7 9 9 9 5 Autophagy protein 16 (ATG16) Filament PF00038.21 ORY24547.1 - 0.001 18.7 4.8 0.001 18.7 4.8 8.3 2 2 4 7 7 7 5 Intermediate filament protein GAS PF13851.6 ORY24547.1 - 0.0013 18.1 6.5 0.0013 18.1 6.5 8.9 3 2 5 8 8 8 3 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 ORY24547.1 - 0.0053 16.8 12.5 0.0053 16.8 12.5 10.6 4 2 3 8 8 8 3 TPR/MLP1/MLP2-like protein HrpB7 PF09486.10 ORY24547.1 - 0.01 16.2 3.2 0.01 16.2 3.2 8.7 5 4 2 8 8 8 0 Bacterial type III secretion protein (HrpB7) ZapB PF06005.12 ORY24547.1 - 0.017 15.5 2.9 0.017 15.5 2.9 13.3 5 4 4 9 9 7 0 Cell division protein ZapB Ribosomal_L3 PF00297.22 ORY24547.1 - 0.23 10.4 1.3 0.85 8.5 0.2 2.3 1 1 1 2 2 2 0 Ribosomal protein L3 GAIN_A PF18619.1 ORY24547.1 - 0.51 10.6 4.5 30 4.9 0.7 4.7 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A HOOK PF05622.12 ORY24547.1 - 0.93 7.6 102.9 0.073 11.2 66.5 5.4 4 1 1 5 5 5 0 HOOK protein CENP-F_leu_zip PF10473.9 ORY24547.1 - 4.5 7.3 132.2 0.051 13.6 3.5 10.4 4 2 5 9 9 9 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MAD PF05557.13 ORY24547.1 - 7.9 4.7 102.9 0.0042 15.5 23.4 5.4 3 1 2 5 5 5 0 Mitotic checkpoint protein DUF1192 PF06698.11 ORY24547.1 - 9 6.4 25.3 0.64 10.1 0.1 8.2 8 2 1 9 9 9 0 Protein of unknown function (DUF1192) Myosin_head PF00063.21 ORY24548.1 - 1.1e-230 767.4 3.0 2.2e-230 766.5 3.0 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 ORY24548.1 - 1.5e-21 76.6 0.8 1.4e-20 73.5 0.0 2.7 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 ORY24548.1 - 2.5e-11 42.3 10.8 1.5e-06 27.4 2.0 4.8 4 0 0 4 4 4 2 IQ calmodulin-binding motif DUF4201 PF13870.6 ORY24548.1 - 1.2e-05 25.1 6.6 1.2e-05 25.1 6.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) Spc7 PF08317.11 ORY24548.1 - 0.00085 18.3 14.0 0.0025 16.8 14.0 1.7 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_22 PF13401.6 ORY24548.1 - 0.0064 16.8 0.8 0.022 15.0 0.0 2.3 2 0 0 2 2 1 1 AAA domain Laminin_I PF06008.14 ORY24548.1 - 0.013 15.2 11.6 0.029 14.1 11.6 1.5 1 0 0 1 1 1 0 Laminin Domain I Tropomyosin_1 PF12718.7 ORY24548.1 - 0.027 14.6 11.3 0.092 12.9 11.3 1.9 1 0 0 1 1 1 0 Tropomyosin like AAA_16 PF13191.6 ORY24548.1 - 0.039 14.3 0.6 0.13 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain PI3K_P85_iSH2 PF16454.5 ORY24548.1 - 0.069 12.7 5.9 3.7 7.1 0.6 2.6 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Csm4_C PF17953.1 ORY24548.1 - 0.076 12.9 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 CRISPR Csm4 C-terminal domain NPV_P10 PF05531.12 ORY24548.1 - 0.63 10.5 3.5 14 6.2 0.2 3.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TMF_DNA_bd PF12329.8 ORY24548.1 - 0.65 10.0 17.2 2.2 8.4 9.5 3.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding ERM PF00769.19 ORY24548.1 - 0.65 9.8 20.3 1.4 8.7 20.3 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Swi5 PF07061.11 ORY24548.1 - 0.94 9.6 3.8 1.6 8.9 1.5 2.6 1 1 1 2 2 2 0 Swi5 Bap31_Bap29_C PF18035.1 ORY24548.1 - 0.99 9.5 11.2 0.6 10.2 3.5 2.9 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4140 PF13600.6 ORY24548.1 - 4 7.9 5.8 23 5.5 5.6 2.5 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Troponin PF00992.20 ORY24548.1 - 4.5 7.6 18.4 0.13 12.5 10.1 2.5 2 0 0 2 2 2 0 Troponin ATG16 PF08614.11 ORY24548.1 - 6.3 7.0 22.5 45 4.2 22.5 2.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF2205 PF10224.9 ORY24548.1 - 8.4 6.5 7.2 32 4.6 1.5 3.0 2 0 0 2 2 2 0 Short coiled-coil protein Methyltransf_16 PF10294.9 ORY24640.1 - 3e-05 23.8 0.1 4.9e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 ORY24640.1 - 0.0033 17.0 0.1 0.0053 16.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Branch PF02485.21 ORY24641.1 - 1.2e-25 90.5 0.1 2.4e-25 89.5 0.1 1.4 1 1 0 1 1 1 1 Core-2/I-Branching enzyme PLAC8 PF04749.17 ORY24642.1 - 3.7e-14 53.5 14.5 4.5e-14 53.3 14.5 1.1 1 0 0 1 1 1 1 PLAC8 family UvrB PF12344.8 ORY24642.1 - 0.073 12.9 0.2 6 6.8 0.0 2.2 2 0 0 2 2 2 0 Ultra-violet resistance protein B GTP_CH_N PF12471.8 ORY24643.1 - 3.9e-81 271.5 0.0 5.8e-81 270.9 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 ORY24643.1 - 2.1e-15 56.7 0.0 3e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF4611 PF15387.6 ORY24644.1 - 0.015 15.5 1.8 0.071 13.3 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) DUF2428 PF10350.9 ORY24644.1 - 0.045 13.0 0.4 0.073 12.3 0.1 1.4 1 1 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) DUF4763 PF15960.5 ORY24644.1 - 0.9 8.8 3.0 0.44 9.8 1.1 1.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) DUF2635 PF10948.8 ORY24645.1 - 0.16 11.7 0.1 0.32 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) PAN_1 PF00024.26 ORY24646.1 - 3.6e-23 81.3 1.4 0.00011 22.1 0.0 4.1 4 0 0 4 4 4 4 PAN domain PAN_4 PF14295.6 ORY24646.1 - 7.2e-19 67.4 15.6 5.8e-07 29.3 0.7 4.6 4 1 0 4 4 4 4 PAN domain PAN_3 PF08277.12 ORY24646.1 - 1.1e-08 34.8 17.7 0.0031 17.3 0.4 4.2 4 0 0 4 4 4 4 PAN-like domain PAN_2 PF08276.11 ORY24646.1 - 0.012 15.7 19.6 0.78 9.9 0.2 4.2 4 0 0 4 4 4 0 PAN-like domain CnrY PF17524.2 ORY24646.1 - 0.059 13.6 0.2 0.12 12.6 0.2 1.5 1 0 0 1 1 1 0 Anti-sigma factor CnrY Lactamase_B PF00753.27 ORY24647.1 - 3e-05 24.1 0.1 8.7e-05 22.6 0.1 1.8 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY24647.1 - 0.00063 19.3 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DEAD PF00270.29 ORY24648.1 - 1.4e-44 152.0 0.0 2.5e-44 151.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY24648.1 - 1.4e-29 102.6 0.0 3.8e-28 98.0 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY24648.1 - 8.3e-07 29.2 0.0 5.5e-06 26.5 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY24648.1 - 0.047 14.0 0.4 0.41 10.9 0.4 2.4 1 1 0 1 1 1 0 AAA domain DUF4709 PF15821.5 ORY24651.1 - 0.0049 17.1 1.3 0.0049 17.1 1.3 4.3 2 1 2 4 4 4 2 Domain of unknown function (DUF4709) SAM_2 PF07647.17 ORY24651.1 - 0.023 14.8 0.3 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) ApbA_C PF08546.11 ORY24651.1 - 0.74 10.0 4.5 1.3 9.3 0.2 2.6 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal YtxH PF12732.7 ORY24651.1 - 0.81 10.3 6.3 21 5.8 0.6 4.1 3 1 0 3 3 3 0 YtxH-like protein Sec2p PF06428.11 ORY24651.1 - 1.2 9.1 17.6 0.16 12.0 1.8 3.1 3 0 0 3 3 3 0 GDP/GTP exchange factor Sec2p Vir_act_alpha_C PF10400.9 ORY24651.1 - 7 7.4 7.2 6.9 7.4 0.1 3.6 3 0 0 3 3 3 0 Virulence activator alpha C-term Branch PF02485.21 ORY24652.1 - 3.2e-27 95.6 0.1 5.6e-27 94.8 0.1 1.4 1 0 0 1 1 1 1 Core-2/I-Branching enzyme zf-C2H2_10 PF16588.5 ORY24654.1 - 0.55 10.0 9.0 1.2 9.0 9.0 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger zf-C2H2_10 PF16588.5 ORY24656.1 - 0.55 10.0 9.0 1.2 9.0 9.0 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger RRM_1 PF00076.22 ORY24749.1 - 2.4e-06 27.3 0.0 7.1e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAM_adeno_trans PF01887.16 ORY24749.1 - 0.025 14.0 0.2 0.043 13.2 0.2 1.4 1 0 0 1 1 1 0 S-adenosyl-l-methionine hydroxide adenosyltransferase Sigma70_r1_1 PF03979.14 ORY24749.1 - 0.038 14.0 0.1 0.14 12.2 0.1 1.9 1 1 1 2 2 2 0 Sigma-70 factor, region 1.1 HNHc_6 PF16784.5 ORY24749.1 - 0.084 12.4 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Putative HNHc nuclease Esterase_phd PF10503.9 ORY24749.1 - 0.085 12.3 0.1 0.66 9.4 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase Helicase_IV_N PF12462.8 ORY24749.1 - 0.13 12.1 0.2 0.28 11.1 0.2 1.5 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal Myb_DNA-bind_3 PF12776.7 ORY24799.1 - 1.4e-06 29.2 0.2 3.4e-06 27.9 0.1 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Collagen PF01391.18 ORY24799.1 - 0.0007 19.3 3.8 0.0013 18.4 3.8 1.4 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Myb_DNA-bind_4 PF13837.6 ORY24799.1 - 0.0042 17.4 0.3 0.0091 16.4 0.3 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF2389 PF09493.10 ORY24799.1 - 0.069 13.8 0.4 0.14 12.8 0.4 1.5 1 0 0 1 1 1 0 Tryptophan-rich protein (DUF2389) Nop14 PF04147.12 ORY24799.1 - 2.9 6.0 6.0 3.9 5.6 6.0 1.2 1 0 0 1 1 1 0 Nop14-like family p450 PF00067.22 ORY24800.1 - 7.8e-34 117.2 0.0 9.6e-34 116.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ORY24801.1 - 9.9e-73 245.4 0.0 1.3e-72 245.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2600 PF10776.9 ORY24801.1 - 0.095 11.6 0.0 0.21 10.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2600) Fungal_trans PF04082.18 ORY24802.1 - 0.0023 17.0 0.2 0.0045 16.1 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain CSN5_C PF18323.1 ORY24802.1 - 0.15 13.0 0.1 1 10.3 0.1 2.3 2 0 0 2 2 2 0 Cop9 signalosome subunit 5 C-terminal domain BST2 PF16716.5 ORY24802.1 - 0.69 10.5 4.0 0.7 10.5 1.1 2.3 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 NAD_binding_10 PF13460.6 ORY24843.1 - 0.00073 19.5 0.0 0.0017 18.3 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY24843.1 - 0.026 14.1 0.0 0.042 13.4 0.0 1.4 1 1 0 1 1 1 0 NmrA-like family Glyco_hydro_20 PF00728.22 ORY24844.1 - 2.5e-21 76.5 0.0 3.3e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Helicase_C_2 PF13307.6 ORY24846.1 - 3e-56 190.3 0.0 6.5e-56 189.2 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 ORY24846.1 - 8.5e-54 181.8 0.5 1.4e-53 181.1 0.5 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 ORY24846.1 - 0.002 18.2 0.1 1.1 9.2 0.1 2.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY24846.1 - 0.021 14.6 0.0 1.9 8.2 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase Glucos_trans_II PF14264.6 ORY24847.1 - 3.7 6.8 13.0 2.9 7.2 10.0 1.9 2 0 0 2 2 2 0 Glucosyl transferase GtrII Pet191_N PF10203.9 ORY24848.1 - 0.9 9.9 4.3 0.36 11.1 0.7 1.9 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Glug PF07581.12 ORY24848.1 - 4 8.1 9.2 11 6.6 2.1 2.8 2 0 0 2 2 2 0 The GLUG motif Utp14 PF04615.13 ORY24850.1 - 1.3 7.5 19.1 1.9 7.0 19.1 1.2 1 0 0 1 1 1 0 Utp14 protein Peptidase_S8 PF00082.22 ORY24851.1 - 2.1e-31 109.3 1.9 4.4e-31 108.3 1.9 1.5 1 1 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 ORY24851.1 - 1.2e-24 86.1 0.2 2.1e-24 85.3 0.2 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 ORY24851.1 - 1e-08 35.8 0.1 2.2e-08 34.7 0.1 1.6 1 0 0 1 1 1 1 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 ORY24851.1 - 0.0021 18.6 0.1 0.0038 17.7 0.1 1.4 1 0 0 1 1 1 1 N-terminal of Subtilase family HEAT_2 PF13646.6 ORY24853.1 - 1.4e-15 57.5 7.3 0.00017 21.9 0.2 6.8 4 1 3 7 7 7 5 HEAT repeats HEAT PF02985.22 ORY24853.1 - 3.4e-15 54.8 15.3 0.2 12.0 0.0 10.1 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.6 ORY24853.1 - 3.6e-09 36.9 19.5 0.00029 21.3 0.1 9.3 9 1 1 10 10 10 1 HEAT-like repeat Cnd1 PF12717.7 ORY24853.1 - 9.9e-08 32.2 0.4 0.025 14.6 0.1 5.9 4 1 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 ORY24853.1 - 6.7e-06 25.8 0.1 0.17 11.4 0.0 4.6 5 0 0 5 5 5 1 CLASP N terminal Vac14_Fab1_bd PF12755.7 ORY24853.1 - 9.3e-05 22.9 0.0 1.4 9.5 0.0 4.9 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region IFRD PF05004.13 ORY24853.1 - 0.00038 19.7 0.2 0.27 10.3 0.4 4.1 4 1 0 4 4 4 1 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 ORY24853.1 - 0.0061 15.2 0.0 0.013 14.1 0.0 1.5 1 0 0 1 1 1 1 Adaptin N terminal region TIP120 PF08623.10 ORY24853.1 - 0.025 14.3 0.1 0.58 9.9 0.0 3.2 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) RTP1_C1 PF10363.9 ORY24853.1 - 0.038 14.2 0.1 5.1 7.3 0.0 3.7 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 ORY24853.1 - 0.043 13.0 0.3 0.092 11.9 0.3 1.5 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Gly_transf_sug PF04488.15 ORY24854.1 - 2.1e-15 57.1 0.0 4e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Gb3_synth PF04572.12 ORY24854.1 - 0.00017 21.7 0.0 0.00027 21.1 0.0 1.4 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region BCDHK_Adom3 PF10436.9 ORY24935.1 - 0.048 13.5 0.2 2.5 7.9 0.1 2.3 2 1 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF3403 PF11883.8 ORY24936.1 - 0.003 17.6 15.9 3.2 7.9 0.2 7.0 5 3 2 8 8 8 2 Domain of unknown function (DUF3403) MetallophosN PF16371.5 ORY24936.1 - 0.0073 16.6 13.3 25 5.2 0.1 6.1 1 1 4 7 7 7 3 N terminal of Calcineurin-like phosphoesterase DUF3450 PF11932.8 ORY24939.1 - 0.00036 19.9 1.5 0.00044 19.6 1.2 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) Nsp1_C PF05064.13 ORY24939.1 - 0.001 18.8 1.2 0.0011 18.7 1.2 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region ZapB PF06005.12 ORY24939.1 - 0.0018 18.7 5.1 0.0025 18.2 5.1 1.3 1 1 0 1 1 1 1 Cell division protein ZapB BLOC1_2 PF10046.9 ORY24939.1 - 0.0021 18.3 1.1 0.0027 17.9 1.1 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 ORY24939.1 - 0.0031 17.4 0.9 0.0035 17.2 0.9 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 BST2 PF16716.5 ORY24939.1 - 0.0038 17.8 2.3 0.0049 17.4 2.3 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 GAS PF13851.6 ORY24939.1 - 0.0039 16.6 2.9 0.0044 16.4 2.9 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 ORY24939.1 - 0.017 15.1 2.0 0.017 15.1 2.0 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Cluap1 PF10234.9 ORY24939.1 - 0.018 14.4 1.5 0.019 14.4 1.5 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Tropomyosin_1 PF12718.7 ORY24939.1 - 0.024 14.8 2.5 0.036 14.2 2.5 1.4 1 1 0 1 1 1 0 Tropomyosin like YabA PF06156.13 ORY24939.1 - 0.026 15.1 1.3 0.031 14.9 1.3 1.2 1 0 0 1 1 1 0 Initiation control protein YabA HlyD_D23 PF16576.5 ORY24939.1 - 0.028 13.6 1.0 0.03 13.5 1.0 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Herpes_UL6 PF01763.16 ORY24939.1 - 0.028 12.9 1.7 0.029 12.9 1.7 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like BSP PF04450.12 ORY24939.1 - 0.034 14.0 0.0 0.053 13.3 0.0 1.3 1 1 0 1 1 1 0 Peptidase of plants and bacteria Rab_bind PF16704.5 ORY24939.1 - 0.035 14.1 0.3 2.8 8.1 0.1 2.3 1 1 1 2 2 2 0 Rab binding domain DUF948 PF06103.11 ORY24939.1 - 0.041 14.1 0.5 0.058 13.7 0.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 ORY24939.1 - 0.042 14.4 2.8 0.057 14.0 2.8 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 ORY24939.1 - 0.12 13.0 4.7 0.33 11.6 4.7 1.8 1 1 0 1 1 1 0 SlyX Cep57_MT_bd PF06657.13 ORY24939.1 - 0.13 12.7 3.5 1.7 9.2 0.8 2.2 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 XhlA PF10779.9 ORY24939.1 - 0.14 12.3 2.3 0.29 11.4 2.3 1.5 1 0 0 1 1 1 0 Haemolysin XhlA Fib_alpha PF08702.10 ORY24939.1 - 0.15 12.2 3.3 0.49 10.6 3.2 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 ORY24939.1 - 0.25 11.8 2.6 1.1 9.8 2.9 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 ORY24939.1 - 0.62 9.9 5.3 6.3 6.7 0.4 2.0 1 1 1 2 2 2 0 Septum formation initiator DUF3450 PF11932.8 ORY24942.1 - 0.00036 19.9 1.5 0.00044 19.6 1.2 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) Nsp1_C PF05064.13 ORY24942.1 - 0.001 18.8 1.2 0.0011 18.7 1.2 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region ZapB PF06005.12 ORY24942.1 - 0.0018 18.7 5.1 0.0025 18.2 5.1 1.3 1 1 0 1 1 1 1 Cell division protein ZapB BLOC1_2 PF10046.9 ORY24942.1 - 0.0021 18.3 1.1 0.0027 17.9 1.1 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 ORY24942.1 - 0.0031 17.4 0.9 0.0035 17.2 0.9 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 BST2 PF16716.5 ORY24942.1 - 0.0038 17.8 2.3 0.0049 17.4 2.3 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 GAS PF13851.6 ORY24942.1 - 0.0039 16.6 2.9 0.0044 16.4 2.9 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 ORY24942.1 - 0.017 15.1 2.0 0.017 15.1 2.0 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Cluap1 PF10234.9 ORY24942.1 - 0.018 14.4 1.5 0.019 14.4 1.5 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Tropomyosin_1 PF12718.7 ORY24942.1 - 0.024 14.8 2.5 0.036 14.2 2.5 1.4 1 1 0 1 1 1 0 Tropomyosin like YabA PF06156.13 ORY24942.1 - 0.026 15.1 1.3 0.031 14.9 1.3 1.2 1 0 0 1 1 1 0 Initiation control protein YabA HlyD_D23 PF16576.5 ORY24942.1 - 0.028 13.6 1.0 0.03 13.5 1.0 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Herpes_UL6 PF01763.16 ORY24942.1 - 0.028 12.9 1.7 0.029 12.9 1.7 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like BSP PF04450.12 ORY24942.1 - 0.034 14.0 0.0 0.053 13.3 0.0 1.3 1 1 0 1 1 1 0 Peptidase of plants and bacteria Rab_bind PF16704.5 ORY24942.1 - 0.035 14.1 0.3 2.8 8.1 0.1 2.3 1 1 1 2 2 2 0 Rab binding domain DUF948 PF06103.11 ORY24942.1 - 0.041 14.1 0.5 0.058 13.7 0.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 ORY24942.1 - 0.042 14.4 2.8 0.057 14.0 2.8 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 ORY24942.1 - 0.12 13.0 4.7 0.33 11.6 4.7 1.8 1 1 0 1 1 1 0 SlyX Cep57_MT_bd PF06657.13 ORY24942.1 - 0.13 12.7 3.5 1.7 9.2 0.8 2.2 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 XhlA PF10779.9 ORY24942.1 - 0.14 12.3 2.3 0.29 11.4 2.3 1.5 1 0 0 1 1 1 0 Haemolysin XhlA Fib_alpha PF08702.10 ORY24942.1 - 0.15 12.2 3.3 0.49 10.6 3.2 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 ORY24942.1 - 0.25 11.8 2.6 1.1 9.8 2.9 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 ORY24942.1 - 0.62 9.9 5.3 6.3 6.7 0.4 2.0 1 1 1 2 2 2 0 Septum formation initiator WD40 PF00400.32 ORY24943.1 - 4.4e-95 309.0 52.3 6.9e-11 42.5 0.9 12.2 11 1 1 12 12 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY24943.1 - 1.4e-37 127.9 7.0 0.019 15.2 0.0 11.0 1 1 9 10 10 10 10 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY24943.1 - 2.9e-18 65.8 18.4 0.098 11.3 0.0 9.9 1 1 7 9 9 9 8 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORY24943.1 - 1.2e-13 50.8 29.1 0.0027 16.7 0.3 10.3 2 1 5 7 7 7 6 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORY24943.1 - 1.6e-11 44.5 6.4 0.00067 19.6 0.2 5.7 3 1 4 7 7 7 4 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY24943.1 - 2.2e-11 43.6 4.6 0.085 12.2 0.0 6.1 3 1 4 7 7 7 5 WD40-like domain TIR_2 PF13676.6 ORY24943.1 - 2.3e-11 44.4 0.0 5.2e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 TIR domain NACHT PF05729.12 ORY24943.1 - 1.7e-08 34.5 0.3 9.3e-07 28.9 0.1 3.0 2 1 0 2 2 2 1 NACHT domain PD40 PF07676.12 ORY24943.1 - 0.00011 22.0 10.7 63 3.7 0.0 8.9 10 0 0 10 10 9 0 WD40-like Beta Propeller Repeat Plavaka PF18759.1 ORY24943.1 - 0.004 16.4 0.0 1.3 8.2 0.0 4.0 1 1 3 5 5 5 1 Plavaka transposase Spore_IV_A PF09547.10 ORY24943.1 - 0.017 14.1 0.2 0.034 13.1 0.2 1.4 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) AAA_16 PF13191.6 ORY24943.1 - 0.024 15.0 0.0 0.2 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 ORY24943.1 - 0.047 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ORY24943.1 - 0.069 13.5 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 ORY24943.1 - 0.19 11.0 0.1 2.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) WW PF00397.26 ORY24944.1 - 3e-21 75.2 8.1 3.8e-12 46.1 1.3 2.3 2 0 0 2 2 2 2 WW domain Glyco_hyd_101C PF17451.2 ORY24944.1 - 0.019 15.3 2.2 0.15 12.4 0.2 2.1 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain EphA2_TM PF14575.6 ORY24944.1 - 0.089 13.7 0.0 0.15 13.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3986 PF13143.6 ORY25039.1 - 0.06 14.3 0.4 0.24 12.4 0.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3986) UPA_2 PF17809.1 ORY25039.1 - 0.11 12.3 0.1 0.3 10.9 0.1 1.7 1 0 0 1 1 1 0 UPA domain FlaC_arch PF05377.11 ORY25039.1 - 0.23 11.9 4.7 0.4 11.1 1.1 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) CENP-H PF05837.12 ORY25039.1 - 0.27 11.7 4.9 0.41 11.1 1.8 3.0 3 0 0 3 3 3 0 Centromere protein H (CENP-H) YabA PF06156.13 ORY25039.1 - 6.8 7.4 7.2 0.83 10.3 0.6 3.0 3 0 0 3 3 3 0 Initiation control protein YabA DNA_pol_A_exo1 PF01612.20 ORY25040.1 - 0.0019 17.9 0.0 0.0054 16.5 0.0 1.7 2 0 0 2 2 2 1 3'-5' exonuclease tRNA-synt_2c PF01411.19 ORY25094.1 - 3.1e-07 29.3 0.0 4e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 ORY25094.1 - 4.5e-07 29.9 0.9 9.6e-07 28.8 0.9 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain AAA_22 PF13401.6 ORY25095.1 - 0.007 16.6 0.5 1.6 9.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain DUF1664 PF07889.12 ORY25096.1 - 0.032 14.2 0.2 0.032 14.2 0.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Atg14 PF10186.9 ORY25096.1 - 7.3 5.6 16.3 0.4 9.7 4.2 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 PHF5 PF03660.14 ORY25097.1 - 6.3e-50 167.7 8.5 7.1e-50 167.6 8.5 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 ORY25097.1 - 0.011 13.7 2.6 0.012 13.6 2.6 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 ORY25097.1 - 0.1 12.6 9.6 1.6 8.8 1.0 2.5 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_2 PF13639.6 ORY25097.1 - 0.38 11.1 8.6 14 6.2 8.6 2.4 1 1 0 1 1 1 0 Ring finger domain C1_2 PF03107.16 ORY25097.1 - 0.97 9.8 14.2 0.61 10.4 3.0 2.4 1 1 1 2 2 2 0 C1 domain PHD PF00628.29 ORY25097.1 - 2.9 7.8 10.6 7.7 6.5 9.6 2.4 2 1 0 2 2 2 0 PHD-finger RecR PF02132.15 ORY25097.1 - 8.3 6.1 13.7 6.9 6.3 1.2 3.3 3 0 0 3 3 3 0 RecR protein Metallophos PF00149.28 ORY25099.1 - 2.3e-06 28.3 0.0 3.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 ORY25099.1 - 7.7e-06 26.2 0.0 2e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain GH131_N PF18271.1 ORY25101.1 - 0.081 12.6 0.1 0.11 12.1 0.1 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 131 catalytic N-terminal domain NIPSNAP PF07978.13 ORY25102.1 - 3.7e-37 126.6 0.8 3.9e-24 84.8 0.1 2.1 2 0 0 2 2 2 2 NIPSNAP Fe-S_biosyn PF01521.20 ORY25103.1 - 1e-14 54.6 0.0 1.2e-14 54.4 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis NAC PF01849.18 ORY25103.1 - 0.13 12.3 0.3 0.84 9.7 0.3 2.0 1 1 0 1 1 1 0 NAC domain Mnd1 PF03962.15 ORY25104.1 - 1.7e-25 89.0 0.1 3.5e-25 88.1 0.1 1.5 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 ORY25104.1 - 1.1e-19 70.2 0.2 4.3e-19 68.3 0.1 2.1 2 0 0 2 2 2 1 Leucine zipper with capping helix domain ERM PF00769.19 ORY25104.1 - 0.00094 19.1 0.6 0.0012 18.7 0.6 1.3 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Phlebovirus_NSM PF07246.11 ORY25104.1 - 0.15 11.4 1.4 0.21 10.9 1.4 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DivIC PF04977.15 ORY25104.1 - 5.3 6.9 6.4 5.3 6.9 3.1 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF155 PF02582.14 ORY25105.1 - 3.1e-53 180.5 1.1 4.9e-53 179.8 1.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 SPECT1 PF18680.1 ORY25105.1 - 0.012 15.3 0.4 0.094 12.4 0.0 2.2 1 1 1 2 2 2 0 Plasmodium host cell traversal SPECT1 DUF745 PF05335.13 ORY25106.1 - 2e-10 40.7 59.0 0.00063 19.5 22.1 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF745) APG17 PF04108.12 ORY25106.1 - 1e-07 31.5 64.6 0.0051 16.0 20.1 3.3 1 1 2 3 3 3 3 Autophagy protein Apg17 MCPsignal PF00015.21 ORY25106.1 - 2.1e-07 30.9 14.6 0.075 12.8 1.6 3.8 1 1 2 3 3 3 3 Methyl-accepting chemotaxis protein (MCP) signalling domain Nefa_Nip30_N PF10187.9 ORY25106.1 - 1.5e-05 25.3 4.2 1.5e-05 25.3 4.2 3.6 1 1 1 2 2 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF948 PF06103.11 ORY25106.1 - 0.00013 22.2 74.5 1.8e+04 -45.1 74.5 6.1 1 1 0 1 1 0 0 Bacterial protein of unknown function (DUF948) DUF883 PF05957.13 ORY25106.1 - 0.00045 20.8 27.1 6.7 7.4 1.9 6.1 1 1 4 5 5 5 4 Bacterial protein of unknown function (DUF883) Syntaxin_2 PF14523.6 ORY25106.1 - 0.00079 19.8 91.1 1.8e+04 -49.1 91.1 5.1 1 1 0 1 1 0 0 Syntaxin-like protein Laminin_I PF06008.14 ORY25106.1 - 0.0033 17.2 87.9 1.7 8.3 24.0 3.2 1 1 1 2 2 2 2 Laminin Domain I P4Ha_N PF08336.11 ORY25106.1 - 0.0098 15.9 57.9 0.63 10.1 4.8 6.0 1 1 2 3 3 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Glutaredoxin2_C PF04399.13 ORY25106.1 - 0.02 14.7 58.9 6 6.7 5.0 6.6 1 1 4 5 5 4 0 Glutaredoxin 2, C terminal domain RNase_E_G PF10150.9 ORY25106.1 - 0.035 13.5 31.0 1.8e+04 -6.2 31.0 2.8 1 1 0 1 1 0 0 Ribonuclease E/G family ThiG PF05690.14 ORY25106.1 - 0.04 13.2 2.3 0.8 9.0 0.1 3.3 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG YkyA PF10368.9 ORY25106.1 - 0.053 13.2 56.2 3.4 7.3 34.9 2.8 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein Sec34 PF04136.15 ORY25106.1 - 0.053 13.4 74.0 7.2 6.5 12.9 5.0 1 1 4 5 5 5 0 Sec34-like family FliT PF05400.13 ORY25106.1 - 0.85 10.5 47.7 1.8e+04 -31.7 47.7 6.4 1 1 0 1 1 0 0 Flagellar protein FliT CheZ PF04344.13 ORY25106.1 - 1.4 8.8 45.3 22 4.9 12.9 3.5 1 1 2 3 3 3 0 Chemotaxis phosphatase, CheZ Sec20 PF03908.13 ORY25106.1 - 1.6 8.7 61.7 20 5.2 11.5 4.7 1 1 4 5 5 5 0 Sec20 BORCS7 PF16088.5 ORY25106.1 - 2 8.7 65.3 1.8e+04 -36.6 65.3 4.2 1 1 0 1 1 0 0 BLOC-1-related complex sub-unit 7 bVLRF1 PF18826.1 ORY25106.1 - 3.4 7.5 28.5 22 4.9 3.4 4.6 1 1 2 3 3 2 0 bacteroidetes VLRF1 release factor ARGLU PF15346.6 ORY25106.1 - 5.5 6.9 43.4 7.8 6.4 10.6 4.1 1 1 2 3 3 3 0 Arginine and glutamate-rich 1 Perilipin PF03036.16 ORY25106.1 - 5.8 5.8 49.1 2.9 6.8 13.2 2.6 1 1 1 2 2 2 0 Perilipin family GLTSCR1 PF15249.6 ORY25106.1 - 7.3 7.1 36.9 17 5.9 4.5 6.3 1 1 1 2 2 1 0 Conserved region of unknown function on GLTSCR protein LRRNT PF01462.18 ORY25109.1 - 0.057 13.1 0.4 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Rcd1 PF04078.13 ORY25199.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like DUF1664 PF07889.12 ORY25199.1 - 0.17 12.0 0.8 0.41 10.7 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Ank_2 PF12796.7 ORY25201.1 - 1.4e-05 25.6 0.0 0.0012 19.3 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY25201.1 - 3.1e-05 24.2 0.1 0.54 10.8 0.1 4.4 3 0 0 3 3 3 1 Ankyrin repeat F-box-like PF12937.7 ORY25201.1 - 0.012 15.5 0.1 0.035 14.0 0.1 1.8 1 0 0 1 1 1 0 F-box-like Ank_5 PF13857.6 ORY25201.1 - 0.017 15.4 0.1 23 5.5 0.0 4.2 2 1 2 4 4 4 0 Ankyrin repeats (many copies) F-box PF00646.33 ORY25201.1 - 0.018 14.9 0.0 0.066 13.1 0.0 2.1 1 0 0 1 1 1 0 F-box domain PRANC PF09372.10 ORY25201.1 - 0.072 13.4 0.1 0.2 12.0 0.1 1.7 1 0 0 1 1 1 0 PRANC domain Ank_3 PF13606.6 ORY25201.1 - 0.091 13.4 0.0 35 5.4 0.0 4.8 6 0 0 6 6 6 0 Ankyrin repeat DDE_1 PF03184.19 ORY25282.1 - 3.1e-05 23.7 0.0 6.1e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1843 PF08898.10 ORY25283.1 - 0.0019 18.7 3.1 0.17 12.4 0.4 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1843) WEMBL PF05701.11 ORY25283.1 - 0.015 14.0 0.1 0.018 13.8 0.1 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Thiamine_BP PF01910.17 ORY25374.1 - 1.6e-14 53.6 0.0 1.9e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Thiamine-binding protein Lactamase_B_2 PF12706.7 ORY25375.1 - 2.8e-10 40.0 0.1 0.00013 21.5 0.1 2.9 3 0 0 3 3 3 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY25375.1 - 3.3e-09 37.0 0.3 1.5e-08 34.9 0.1 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 ORY25375.1 - 0.0025 17.5 0.0 0.37 10.5 0.0 2.4 2 0 0 2 2 2 2 tRNase Z endonuclease adh_short PF00106.25 ORY25376.1 - 2.7e-33 115.1 0.0 1.9e-28 99.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY25376.1 - 2.8e-20 72.9 0.0 2.5e-19 69.8 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY25376.1 - 7.3e-12 45.5 0.0 1.2e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY25376.1 - 0.00012 21.7 0.1 0.00039 20.0 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 ORY25376.1 - 0.0031 16.9 0.3 0.0049 16.2 0.3 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YjeF_N PF03853.15 ORY25376.1 - 0.016 15.1 0.2 0.033 14.1 0.2 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus DUF3889 PF13028.6 ORY25376.1 - 0.027 14.4 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) RmlD_sub_bind PF04321.17 ORY25376.1 - 0.094 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Ribosomal_S24e PF01282.19 ORY25377.1 - 2.5e-34 117.1 0.0 2.5e-34 117.1 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein S24e NBD_C PF17042.5 ORY25379.1 - 0.22 12.0 2.2 0.32 11.5 2.2 1.2 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain DUF726 PF05277.12 ORY25380.1 - 4.9e-06 25.7 0.3 0.034 13.1 0.3 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF726) LIDHydrolase PF10230.9 ORY25380.1 - 0.0099 15.5 0.0 0.41 10.2 0.1 2.2 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 ORY25380.1 - 0.16 12.5 0.3 0.29 11.7 0.4 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family zf-A20 PF01754.16 ORY25380.1 - 2.7 8.0 7.0 21 5.2 0.3 2.8 2 0 0 2 2 2 0 A20-like zinc finger VWC PF00093.18 ORY25380.1 - 6.1 7.2 9.6 0.5 10.7 4.6 1.8 2 0 0 2 2 2 0 von Willebrand factor type C domain DUF1688 PF07958.11 ORY25382.1 - 1.7e-147 491.6 0.0 1.9e-147 491.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) PALP PF00291.25 ORY25383.1 - 4.1e-64 216.8 0.0 4.8e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Succ_CoA_lig PF13607.6 ORY25383.1 - 0.098 12.5 0.1 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain Pro_isomerase PF00160.21 ORY25384.1 - 4.2e-96 319.6 5.6 1.6e-47 161.7 0.3 2.1 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PALP PF00291.25 ORY25385.1 - 8.4e-61 205.9 0.1 9.7e-61 205.7 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AAA_16 PF13191.6 ORY25387.1 - 8.7e-07 29.5 0.0 4.6e-06 27.1 0.0 2.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 ORY25387.1 - 0.00029 21.1 0.0 0.018 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 ORY25387.1 - 0.0018 18.2 0.0 0.0047 16.9 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 ORY25387.1 - 0.002 18.4 0.1 0.017 15.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ORY25387.1 - 0.0022 18.0 0.0 0.057 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 ORY25387.1 - 0.014 14.6 0.0 0.058 12.6 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 ORY25387.1 - 0.017 15.6 0.0 0.12 12.7 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T-box_assoc PF16176.5 ORY25387.1 - 0.072 13.2 0.3 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 T-box transcription factor-associated RNA_helicase PF00910.22 ORY25387.1 - 0.076 13.4 0.0 0.28 11.6 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Apolipoprotein PF01442.18 ORY25387.1 - 0.094 12.6 6.4 0.49 10.3 4.2 2.8 3 2 0 3 3 3 0 Apolipoprotein A1/A4/E domain MCC-bdg_PDZ PF10506.9 ORY25387.1 - 2.4 8.2 7.9 5.4 7.1 0.0 3.6 4 0 0 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Ank_2 PF12796.7 ORY25388.1 - 4.1e-40 136.3 10.1 2.4e-15 56.9 0.4 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 ORY25388.1 - 2.7e-31 106.6 2.7 1.1e-08 35.1 0.1 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 ORY25388.1 - 2.4e-30 104.5 4.8 3.8e-12 46.5 0.4 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY25388.1 - 1.7e-22 79.1 10.5 2e-07 31.2 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY25388.1 - 4.1e-22 75.9 0.8 1.3e-05 25.2 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat pRN1_helical PF13010.6 ORY25388.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.4 1 1 0 1 1 1 0 Primase helical domain CD4-extracel PF09191.10 ORY25389.1 - 0.063 13.7 0.8 0.32 11.4 0.3 2.1 2 0 0 2 2 2 0 CD4, extracellular AlaDh_PNT_C PF01262.21 ORY25480.1 - 1.7e-06 27.5 0.0 2.6 7.3 0.0 5.6 2 1 4 6 6 6 1 Alanine dehydrogenase/PNT, C-terminal domain DUF4392 PF14336.6 ORY25480.1 - 0.00053 19.5 0.5 1.1e+02 2.0 0.0 5.6 5 1 1 6 6 6 0 Domain of unknown function (DUF4392) DUF2839 PF10999.8 ORY25480.1 - 0.0015 18.8 0.2 1.3e+02 3.1 0.0 5.6 6 0 0 6 6 6 0 Protein of unknown function (DUF2839) Med9 PF07544.13 ORY25480.1 - 0.09 12.9 0.3 5.4e+02 0.8 0.0 4.8 6 0 0 6 6 6 0 RNA polymerase II transcription mediator complex subunit 9 DUF346 PF03984.13 ORY25480.1 - 7 6.5 15.8 2.1e+02 1.8 0.0 6.8 7 0 0 7 7 7 0 Repeat of unknown function (DUF346) DUF348 PF03990.14 ORY25480.1 - 7.8 6.3 25.9 9 6.1 0.2 6.3 6 0 0 6 6 6 0 G5-linked-Ubiquitin-like domain RTP1_C2 PF10304.9 ORY25481.1 - 0.12 12.1 0.4 0.16 11.7 0.4 1.1 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 2 Paramyxo_ncap PF00973.19 ORY25481.1 - 0.14 11.0 0.0 0.16 10.9 0.0 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein LPMO_10 PF03067.15 ORY25483.1 - 6.1e-05 23.8 0.2 6.1e-05 23.8 0.2 2.3 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Cnd3 PF12719.7 ORY25484.1 - 1.8e-60 204.6 8.0 3.3e-59 200.5 1.0 3.3 4 0 0 4 4 4 2 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 ORY25484.1 - 7.2e-08 32.7 0.6 3.1e-05 24.3 0.1 4.0 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.22 ORY25484.1 - 0.032 14.5 11.2 12 6.4 0.1 6.6 8 0 0 8 8 8 0 HEAT repeat HEAT_EZ PF13513.6 ORY25484.1 - 0.041 14.4 1.1 0.93 10.1 0.0 4.0 5 0 0 5 5 5 0 HEAT-like repeat zf-like PF04071.12 ORY25484.1 - 0.15 12.0 0.0 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 Cysteine-rich small domain API5 PF05918.11 ORY25484.1 - 0.21 10.4 2.0 0.61 8.8 0.1 2.4 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) bZIP_1 PF00170.21 ORY25485.1 - 0.00013 22.0 10.4 0.00029 20.9 6.6 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORY25485.1 - 0.0069 16.4 15.2 0.011 15.8 6.6 2.2 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 ORY25486.1 - 0.0013 18.8 11.2 0.0015 18.6 7.6 2.6 2 0 0 2 2 2 1 bZIP transcription factor Mt_ATP-synt_B PF05405.14 ORY25486.1 - 0.031 13.9 1.9 0.39 10.3 0.2 2.5 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) NRDE-2 PF08424.10 ORY25486.1 - 0.056 12.6 1.2 6.5 5.8 0.1 2.3 2 0 0 2 2 2 0 NRDE-2, necessary for RNA interference SNAPc19 PF15497.6 ORY25486.1 - 0.17 12.4 3.8 3.5 8.1 3.8 2.7 1 1 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 PIN_12 PF16289.5 ORY25486.1 - 0.43 11.1 3.7 1.6 9.2 0.5 2.6 3 0 0 3 3 3 0 PIN domain bZIP_2 PF07716.15 ORY25486.1 - 1.7 8.8 16.1 0.25 11.4 8.8 2.5 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 ORY25487.1 - 0.0016 18.5 10.4 0.0016 18.5 10.4 2.8 3 0 0 3 3 3 1 bZIP transcription factor DUF2937 PF11157.8 ORY25487.1 - 0.008 15.9 0.5 0.11 12.1 0.1 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2937) Mvb12 PF09452.10 ORY25487.1 - 0.03 14.8 0.5 0.09 13.2 0.0 2.0 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 Adaptin_binding PF10199.9 ORY25487.1 - 0.049 14.2 4.2 4 8.1 2.9 2.5 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 DUF4633 PF15464.6 ORY25487.1 - 0.11 12.6 2.4 12 6.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) MINDY_DUB PF04424.13 ORY25487.1 - 0.15 12.1 0.7 0.31 11.1 0.1 1.8 2 0 0 2 2 2 0 MINDY deubiquitinase SIKE PF05769.11 ORY25487.1 - 0.21 11.5 4.0 1.6 8.6 2.5 2.4 2 0 0 2 2 2 0 SIKE family REV PF00424.18 ORY25487.1 - 0.79 9.8 4.5 1 9.4 3.1 2.0 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) tRNA_Me_trans PF03054.16 ORY25512.1 - 0.063 12.1 1.3 0.088 11.6 1.3 1.1 1 0 0 1 1 1 0 tRNA methyl transferase Glyco_hydro_15 PF00723.21 ORY25608.1 - 8.7e-41 140.1 0.3 5.6e-40 137.5 0.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 zf-C2H2_12 PF18658.1 ORY25611.1 - 0.032 13.8 0.2 0.06 12.9 0.2 1.5 1 0 0 1 1 1 0 Zinc-finger C2H2-type zf-BED PF02892.15 ORY25611.1 - 0.062 13.3 0.5 0.062 13.3 0.5 2.2 3 0 0 3 3 3 0 BED zinc finger MASE4 PF17158.4 ORY25613.1 - 0.27 10.5 0.2 0.4 9.9 0.2 1.1 1 0 0 1 1 1 0 Membrane-associated sensor, integral membrane domain Asp PF00026.23 ORY25665.1 - 1.4e-18 67.4 6.1 5.3e-18 65.5 6.1 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp PF00026.23 ORY25666.1 - 5e-29 101.7 0.2 6.4e-29 101.4 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 ORY25666.1 - 2.5e-09 37.1 0.4 7.8e-07 29.0 0.0 2.1 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal Galactosyl_T PF01762.21 ORY25667.1 - 1.3e-12 48.0 0.0 1.1e-08 35.1 0.0 2.1 1 1 1 2 2 2 2 Galactosyltransferase Vezatin PF12632.7 ORY25668.1 - 0.018 14.4 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes FixQ PF05545.11 ORY25669.1 - 0.32 11.0 2.7 0.65 10.0 2.7 1.5 1 1 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ cNMP_binding PF00027.29 ORY25670.1 - 9e-12 44.9 0.0 2.6e-11 43.4 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain RRP36 PF06102.12 ORY25672.1 - 2.2e-36 125.3 27.2 3.4e-36 124.7 27.2 1.3 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 Endonuc_Holl PF10107.9 ORY25672.1 - 1.9 8.3 10.4 0.67 9.8 6.8 1.9 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase DUF3306 PF11748.8 ORY25672.1 - 2.3 9.1 12.7 0.53 11.2 6.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Pox_Ag35 PF03286.14 ORY25673.1 - 0.22 11.3 14.3 0.27 11.0 14.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4662 PF15578.6 ORY25673.1 - 0.26 11.0 5.5 0.31 10.8 5.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) CCDC53 PF10152.9 ORY25673.1 - 0.6 10.5 6.6 0.76 10.2 6.6 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF3530 PF12048.8 ORY25673.1 - 0.75 9.1 6.5 0.9 8.9 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) GAGA_bind PF06217.12 ORY25673.1 - 1.2 9.3 8.8 1.4 9.2 8.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family FGF-BP1 PF06473.12 ORY25673.1 - 1.7 8.4 11.2 2 8.2 11.2 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Presenilin PF01080.17 ORY25673.1 - 3.6 6.3 4.3 3.7 6.2 4.3 1.0 1 0 0 1 1 1 0 Presenilin DUF4337 PF14235.6 ORY25673.1 - 5.4 7.1 7.5 6.9 6.8 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) cNMP_binding PF00027.29 ORY25674.1 - 1e-13 51.2 0.0 4.4e-13 49.1 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain HSBP1 PF06825.12 ORY25674.1 - 0.052 13.4 0.2 0.052 13.4 0.2 1.7 2 0 0 2 2 2 0 Heat shock factor binding protein 1 DNA_topoisoIV PF00521.20 ORY25674.1 - 0.07 12.0 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A RE_HaeII PF09554.10 ORY25674.1 - 0.1 11.8 0.3 0.25 10.6 0.1 1.6 2 0 0 2 2 2 0 HaeII restriction endonuclease RRP36 PF06102.12 ORY25675.1 - 2.9e-10 40.4 0.5 2.9e-10 40.4 0.5 1.8 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 cNMP_binding PF00027.29 ORY25676.1 - 4.8e-17 61.8 0.0 1.8e-16 60.0 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain HSBP1 PF06825.12 ORY25676.1 - 0.055 13.3 0.2 0.055 13.3 0.2 1.7 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Coilin_N PF15862.5 ORY25858.1 - 6.1e-05 22.8 7.3 6.1e-05 22.8 7.3 4.5 1 1 3 4 4 4 1 Coilin N-terminus DUF936 PF06075.12 ORY25858.1 - 0.93 8.3 47.2 1.1 8.0 47.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Peptidase_C23 PF05379.11 ORY25861.1 - 0.098 12.8 0.1 0.24 11.5 0.1 1.7 1 1 0 1 1 1 0 Carlavirus endopeptidase NAD_binding_2 PF03446.15 ORY25862.1 - 1.6e-38 132.4 1.9 2.4e-38 131.8 1.9 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ORY25862.1 - 1.1e-33 116.1 0.1 2.6e-33 114.8 0.0 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 ORY25862.1 - 0.0017 18.9 0.0 0.0053 17.3 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 ORY25862.1 - 0.0056 16.1 0.1 0.016 14.6 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Inhibitor_I67 PF11405.8 ORY25862.1 - 0.18 12.1 0.1 0.32 11.3 0.1 1.4 1 0 0 1 1 1 0 Bromelain inhibitor VI WAP PF00095.21 ORY25863.1 - 0.017 15.5 67.6 0.15 12.5 6.0 6.2 6 0 0 6 6 6 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Dickkopf_N PF04706.12 ORY25863.1 - 0.058 13.9 49.4 0.084 13.4 0.9 5.9 6 0 0 6 6 6 0 Dickkopf N-terminal cysteine-rich region Motile_Sperm PF00635.26 ORY25864.1 - 1.9e-13 50.2 0.8 1.4e-12 47.4 0.7 2.1 2 1 0 2 2 2 1 MSP (Major sperm protein) domain PapD_N PF00345.20 ORY25864.1 - 0.007 16.3 0.6 0.014 15.3 0.6 1.5 1 0 0 1 1 1 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain Isochorismatase PF00857.20 ORY25865.1 - 1.8e-12 47.8 0.0 4.3e-12 46.6 0.0 1.7 1 1 0 1 1 1 1 Isochorismatase family YchF-GTPase_C PF06071.13 ORY25867.1 - 8.5e-34 115.6 0.6 1.7e-33 114.6 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 ORY25867.1 - 1.2e-19 70.5 0.1 5.2e-19 68.4 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY25867.1 - 2e-06 27.4 0.0 4.1e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 ORY25867.1 - 0.03 14.3 0.6 0.11 12.5 0.0 2.3 2 1 0 2 2 2 0 TGS domain Fungal_trans PF04082.18 ORY25868.1 - 1.2e-05 24.5 0.3 2.6e-05 23.4 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain CK2S PF15011.6 ORY25868.1 - 0.095 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Casein Kinase 2 substrate MAP17 PF15807.5 ORY25913.1 - 0.042 14.1 0.1 0.047 13.9 0.1 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 AP_endonuc_2 PF01261.24 ORY25963.1 - 0.031 13.7 0.0 0.084 12.3 0.0 1.6 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Flp_N PF03930.14 ORY25963.1 - 0.16 11.9 1.0 0.46 10.5 1.0 1.7 1 0 0 1 1 1 0 Recombinase Flp protein N-terminus zf-TFIIB PF13453.6 ORY25965.1 - 0.081 12.3 0.7 3 7.2 0.1 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger RICTOR_phospho PF14665.6 ORY25967.1 - 0.031 14.6 0.9 0.058 13.7 0.9 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site NOA36 PF06524.12 ORY25968.1 - 0.18 11.1 6.1 0.2 10.9 6.1 1.1 1 0 0 1 1 1 0 NOA36 protein Cep57_CLD_2 PF14197.6 ORY26005.1 - 0.0032 17.5 1.5 0.0066 16.5 1.5 1.5 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 GAS PF13851.6 ORY26005.1 - 0.011 15.2 0.9 0.014 14.8 0.9 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.7 ORY26005.1 - 0.018 15.2 0.7 0.025 14.7 0.7 1.2 1 0 0 1 1 1 0 Tropomyosin like CENP-Q PF13094.6 ORY26005.1 - 0.2 11.9 3.6 0.3 11.3 3.3 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit p450 PF00067.22 ORY26006.1 - 2.4e-30 105.7 0.3 2.3e-24 86.0 0.1 2.3 2 0 0 2 2 2 2 Cytochrome P450 zf-MYND PF01753.18 ORY26007.1 - 5.2e-07 29.6 7.9 9.7e-07 28.8 7.9 1.5 1 0 0 1 1 1 1 MYND finger DUF4449 PF14613.6 ORY26008.1 - 0.01 16.0 0.0 0.07 13.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4449) RhoGAP PF00620.27 ORY26009.1 - 7e-09 35.7 0.1 1.8e-08 34.4 0.0 1.7 2 0 0 2 2 2 1 RhoGAP domain DUF3050 PF11251.8 ORY26009.1 - 0.014 15.0 0.2 0.025 14.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) RRM_1 PF00076.22 ORY26010.1 - 3.8e-83 273.3 2.9 1.8e-22 78.9 0.3 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 ORY26010.1 - 3.4e-27 94.4 0.4 2.6e-26 91.6 0.4 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain CbiG_mid PF11761.8 ORY26010.1 - 4e-06 26.9 0.0 3.8 7.7 0.0 3.5 2 1 1 3 3 3 3 Cobalamin biosynthesis central region YflT PF11181.8 ORY26010.1 - 6.4e-05 23.4 2.2 0.11 13.0 1.1 2.8 3 0 0 3 3 3 2 Heat induced stress protein YflT RRM_occluded PF16842.5 ORY26010.1 - 0.00036 20.3 0.0 0.14 12.0 0.0 3.4 3 1 0 3 3 3 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 ORY26010.1 - 0.0024 17.8 0.5 3.4 7.7 0.0 3.8 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 ORY26010.1 - 0.0024 17.9 0.2 10 6.3 0.0 4.5 4 2 0 4 4 4 1 RNA recognition motif OB_RNB PF08206.11 ORY26010.1 - 0.0034 17.0 0.2 4.8 6.9 0.0 3.4 3 0 0 3 3 3 1 Ribonuclease B OB domain Limkain-b1 PF11608.8 ORY26010.1 - 0.038 14.1 1.1 8.4 6.6 0.2 3.4 3 1 1 4 4 4 0 Limkain b1 RRM_3 PF08777.11 ORY26010.1 - 0.2 11.7 9.8 18 5.4 5.7 3.3 2 1 1 3 3 3 0 RNA binding motif UPF0524 PF15823.5 ORY26010.1 - 0.51 9.7 3.0 6.3 6.1 0.3 2.2 2 0 0 2 2 2 0 UPF0524 of C3orf70 WD40 PF00400.32 ORY26011.1 - 3.7e-08 33.9 10.6 0.00068 20.4 0.5 4.2 3 1 1 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY26011.1 - 5.6e-05 23.4 0.1 0.076 13.3 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF896 PF05979.12 ORY26011.1 - 0.052 13.4 0.2 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) B_lectin PF01453.24 ORY26014.1 - 0.11 13.1 0.2 0.63 10.6 0.0 2.0 1 1 1 2 2 2 0 D-mannose binding lectin Gb3_synth PF04572.12 ORY26125.1 - 4.3e-24 85.1 0.0 5.1e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region AA_permease PF00324.21 ORY26224.1 - 3.1e-109 365.7 39.7 3.7e-109 365.5 39.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY26224.1 - 2.1e-37 129.0 43.7 2.7e-37 128.6 43.7 1.2 1 0 0 1 1 1 1 Amino acid permease Nop14 PF04147.12 ORY26280.1 - 0.011 14.0 16.8 0.017 13.4 16.8 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 ORY26280.1 - 0.012 13.9 7.4 0.018 13.4 7.4 1.3 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 ORY26280.1 - 0.17 11.4 12.8 0.31 10.6 12.8 1.3 1 0 0 1 1 1 0 PPP4R2 Plasmodium_Vir PF05795.11 ORY26280.1 - 0.22 10.9 5.6 0.34 10.3 5.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein HSP90 PF00183.18 ORY26280.1 - 0.23 10.3 6.8 0.37 9.6 6.8 1.2 1 0 0 1 1 1 0 Hsp90 protein TRAP_alpha PF03896.16 ORY26280.1 - 0.49 9.6 6.7 0.83 8.8 6.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RPN2_C PF18004.1 ORY26280.1 - 0.59 10.0 10.2 56 3.6 0.0 2.6 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Mpp10 PF04006.12 ORY26280.1 - 0.81 8.1 19.5 1.2 7.5 19.5 1.2 1 0 0 1 1 1 0 Mpp10 protein PI3K_1B_p101 PF10486.9 ORY26280.1 - 0.86 7.3 4.3 1.1 6.9 4.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pox_Ag35 PF03286.14 ORY26280.1 - 1.2 8.8 11.8 3.6 7.3 11.8 1.8 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BUD22 PF09073.10 ORY26280.1 - 1.6 8.0 17.8 2.8 7.2 17.8 1.3 1 0 0 1 1 1 0 BUD22 Paf1 PF03985.13 ORY26280.1 - 2.3 7.1 19.4 3.8 6.4 19.4 1.2 1 0 0 1 1 1 0 Paf1 DUF4637 PF15470.6 ORY26280.1 - 3.2 7.5 15.3 5.8 6.6 15.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Presenilin PF01080.17 ORY26280.1 - 7.1 5.3 5.8 11 4.7 5.8 1.2 1 0 0 1 1 1 0 Presenilin zf-C2H2 PF00096.26 ORY26281.1 - 0.0017 18.7 4.4 0.004 17.5 4.4 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY26281.1 - 0.0026 18.4 3.0 0.0069 17.1 3.0 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY26281.1 - 0.027 14.5 2.4 0.051 13.6 2.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY26281.1 - 0.092 13.1 0.8 0.28 11.5 0.8 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Gti1_Pac2 PF09729.9 ORY26282.1 - 2.9e-27 95.9 0.2 1.1e-21 77.8 0.0 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family DUF2681 PF10883.8 ORY26359.1 - 0.15 12.5 0.1 0.27 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) LRR_4 PF12799.7 ORY26360.1 - 0.028 14.9 2.3 0.086 13.3 2.3 1.9 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY26360.1 - 3.7 8.5 4.9 3.9 8.4 1.1 3.2 3 1 0 3 3 3 0 Leucine Rich Repeat zf-C2H2 PF00096.26 ORY26387.1 - 3.7e-16 58.6 12.5 0.00018 21.8 0.0 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY26387.1 - 1.3e-15 56.7 11.7 0.0072 17.1 0.5 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY26387.1 - 6.4e-09 35.8 16.1 0.003 17.9 0.5 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY26387.1 - 2.4e-06 27.4 10.3 0.11 12.5 0.2 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 ORY26387.1 - 1.4e-05 25.8 7.0 0.033 14.8 0.8 3.3 1 1 1 3 3 3 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 ORY26387.1 - 7.9e-05 22.8 5.1 0.59 10.5 0.2 4.3 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 ORY26387.1 - 0.002 18.4 7.4 0.015 15.5 0.1 3.2 1 1 2 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding Ogr_Delta PF04606.12 ORY26387.1 - 0.0067 16.4 4.0 0.52 10.3 0.6 3.4 3 0 0 3 3 3 1 Ogr/Delta-like zinc finger zf-met PF12874.7 ORY26387.1 - 0.0078 16.6 6.2 1.8 9.0 0.2 4.4 4 0 0 4 4 4 1 Zinc-finger of C2H2 type LUC7 PF03194.15 ORY26387.1 - 0.0079 15.9 4.3 0.071 12.8 0.1 2.1 2 0 0 2 2 2 1 LUC7 N_terminus ADK_lid PF05191.14 ORY26387.1 - 0.01 15.8 0.8 2 8.5 0.3 2.8 2 0 0 2 2 2 0 Adenylate kinase, active site lid TF_Zn_Ribbon PF08271.12 ORY26387.1 - 0.013 15.0 0.5 4.7 6.8 0.1 2.8 2 0 0 2 2 2 0 TFIIB zinc-binding ORC6 PF05460.13 ORY26387.1 - 0.014 14.7 1.0 0.017 14.5 1.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) zf-C2H2_8 PF15909.5 ORY26387.1 - 0.023 15.0 4.9 0.9 9.9 2.7 3.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon UBM PF14377.6 ORY26387.1 - 0.077 12.5 0.4 0.16 11.4 0.4 1.6 1 0 0 1 1 1 0 Ubiquitin binding region zf-MYST PF17772.1 ORY26387.1 - 0.13 11.9 0.3 28 4.4 0.0 3.0 2 0 0 2 2 2 0 MYST family zinc finger domain BolA PF01722.18 ORY26387.1 - 0.31 11.4 1.5 17 5.8 0.0 2.3 2 0 0 2 2 2 0 BolA-like protein C1_2 PF03107.16 ORY26387.1 - 0.34 11.3 5.8 5.8 7.3 3.0 2.8 2 1 0 2 2 2 0 C1 domain zf-C2H2_2 PF12756.7 ORY26387.1 - 0.4 11.0 10.5 59 4.1 2.3 4.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-TRAF PF02176.18 ORY26387.1 - 0.43 11.3 11.5 0.93 10.2 1.8 2.6 1 1 0 2 2 2 0 TRAF-type zinc finger Zn-ribbon_8 PF09723.10 ORY26387.1 - 0.5 10.5 8.0 5.1 7.3 1.3 3.1 2 2 0 2 2 2 0 Zinc ribbon domain zf-U11-48K PF05253.12 ORY26387.1 - 1 9.3 3.7 43 4.2 0.0 3.5 4 0 0 4 4 4 0 U11-48K-like CHHC zinc finger FAR1 PF03101.15 ORY26387.1 - 1.1 10.0 11.3 0.96 10.2 3.6 2.3 1 1 1 2 2 2 0 FAR1 DNA-binding domain OrfB_Zn_ribbon PF07282.11 ORY26387.1 - 5.8 6.9 11.0 15 5.6 0.1 3.7 3 1 1 4 4 4 0 Putative transposase DNA-binding domain Actin_micro PF17003.5 ORY26387.1 - 6.3 5.9 7.7 8.2 5.5 1.1 2.1 2 0 0 2 2 2 0 Putative actin-like family zf-C2H2 PF00096.26 ORY26388.1 - 1.5e-05 25.2 9.6 0.005 17.2 0.1 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY26388.1 - 0.00031 21.3 7.8 0.002 18.8 0.3 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 ORY26388.1 - 0.11 13.2 3.5 0.69 10.6 0.5 2.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2 PF00096.26 ORY26392.1 - 1e-10 41.4 1.4 0.00041 20.7 0.4 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY26392.1 - 1.1e-09 38.3 3.6 9.8e-05 22.9 0.4 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY26392.1 - 6.1e-08 32.7 7.1 0.00019 21.7 0.1 2.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY26392.1 - 2.9e-07 30.3 3.3 0.0014 18.5 1.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY26392.1 - 0.00023 21.3 0.1 0.037 14.3 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 ORY26392.1 - 0.0011 19.2 1.4 0.0013 18.9 1.4 1.2 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 ORY26392.1 - 0.015 14.9 0.3 2.5 7.8 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 ORY26392.1 - 0.023 15.4 2.4 0.21 12.3 0.2 1.9 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2HC_2 PF13913.6 ORY26392.1 - 0.023 14.6 7.5 0.12 12.3 0.2 2.6 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-met PF12874.7 ORY26392.1 - 0.023 15.1 0.1 9.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-MYST PF17772.1 ORY26392.1 - 0.065 12.8 0.2 0.34 10.5 0.2 1.9 1 1 0 1 1 1 0 MYST family zinc finger domain Prok-RING_1 PF14446.6 ORY26392.1 - 0.068 13.1 1.7 1.7 8.6 1.7 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 TF_Zn_Ribbon PF08271.12 ORY26392.1 - 0.088 12.3 1.4 0.2 11.2 1.4 1.6 1 1 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_9 PF14369.6 ORY26392.1 - 0.09 13.1 1.5 9.7 6.5 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon DUF4764 PF15961.5 ORY26392.1 - 0.62 8.7 2.2 2.5 6.7 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4764) zf-C2H2_4 PF13894.6 ORY26393.1 - 3e-07 30.7 4.7 0.017 15.9 1.9 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY26393.1 - 1.4e-05 25.2 4.6 0.0028 18.0 0.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY26393.1 - 0.0046 17.3 5.4 0.15 12.5 0.3 3.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY26393.1 - 0.016 15.2 4.1 0.51 10.4 0.6 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 ORY26393.1 - 0.053 13.8 0.9 1.7 9.0 0.3 2.2 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 ORY26394.1 - 0.00015 22.3 8.5 0.075 13.9 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY26394.1 - 0.0049 16.8 3.1 0.0049 16.8 3.1 2.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY26394.1 - 0.012 16.1 10.1 0.023 15.1 0.2 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type HPIP PF15226.6 ORY26394.1 - 0.021 15.2 1.4 0.032 14.6 0.1 2.0 2 0 0 2 2 2 0 HCF-1 beta-propeller-interacting protein family DUF4298 PF14131.6 ORY26394.1 - 0.034 14.1 0.1 0.066 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) zf-H2C2_2 PF13465.6 ORY26394.1 - 0.12 12.9 8.2 0.37 11.3 1.3 2.9 3 0 0 3 3 3 0 Zinc-finger double domain Ogr_Delta PF04606.12 ORY26394.1 - 0.54 10.3 6.5 5.9 7.0 0.4 3.0 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger zf-C2H2_4 PF13894.6 ORY26395.1 - 4.2e-05 24.0 7.0 0.057 14.3 3.5 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY26395.1 - 0.0011 19.3 7.0 0.071 13.6 0.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ORY26395.1 - 0.0026 17.7 3.7 0.0093 16.0 1.8 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger Ogr_Delta PF04606.12 ORY26395.1 - 0.024 14.6 0.9 2.7 8.0 0.2 2.5 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger zf-H2C2_2 PF13465.6 ORY26395.1 - 0.076 13.5 5.0 1.4 9.5 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY26395.1 - 0.25 11.7 3.2 0.56 10.6 1.8 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ORY26395.1 - 0.44 10.9 4.2 2.4 8.5 0.1 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn_clus PF00172.18 ORY26398.1 - 0.00071 19.7 12.4 0.0011 19.0 12.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4551 PF15087.6 ORY26398.1 - 0.72 8.6 5.3 1 8.1 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Zn_clus PF00172.18 ORY26400.1 - 6e-05 23.1 10.5 0.0001 22.4 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 ORY26401.1 - 2.9e-06 27.3 12.6 4.7e-06 26.6 12.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 ORY26402.1 - 2.5e-07 30.7 10.2 3.8e-07 30.1 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 ORY26403.1 - 1.3e-06 28.4 10.9 2e-06 27.8 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BCDHK_Adom3 PF10436.9 ORY26404.1 - 3.2e-37 127.9 0.0 5.3e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORY26404.1 - 3e-11 43.8 0.0 7.6e-11 42.5 0.0 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORY26404.1 - 0.00013 21.8 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GTP_EFTU PF00009.27 ORY26405.1 - 4.2e-60 202.6 0.5 6.7e-60 202.0 0.5 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 ORY26405.1 - 1e-30 106.0 0.0 2.4e-30 104.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 ORY26405.1 - 1.3e-20 73.2 0.0 2.9e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORY26405.1 - 5.1e-14 52.4 0.4 2.8e-13 50.1 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 ORY26405.1 - 1.9e-12 47.1 0.0 4.3e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 ORY26405.1 - 0.0023 18.0 0.1 0.0051 16.9 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ACPS PF01648.20 ORY26406.1 - 5.6e-09 36.1 0.0 2.8e-08 33.9 0.0 1.9 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Tcf25 PF04910.14 ORY26410.1 - 5.6e-68 229.6 0.0 8.2e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 NARP1 PF12569.8 ORY26410.1 - 0.0099 14.8 15.9 0.082 11.8 0.0 2.2 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 SWIRM-assoc_2 PF16496.5 ORY26410.1 - 0.045 12.6 14.1 0.068 12.0 14.1 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal PGA2 PF07543.12 ORY26410.1 - 0.045 13.7 13.7 0.095 12.7 13.7 1.5 1 0 0 1 1 1 0 Protein trafficking PGA2 GAGA_bind PF06217.12 ORY26410.1 - 1 9.6 16.6 0.043 14.1 10.9 1.6 2 0 0 2 2 2 0 GAGA binding protein-like family TFIIF_alpha PF05793.12 ORY26410.1 - 1.1 7.8 16.4 1.6 7.2 16.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 ORY26410.1 - 3.9 5.7 10.6 5.3 5.2 10.6 1.2 1 0 0 1 1 1 0 CDC45-like protein VSG_B PF13206.6 ORY26410.1 - 4 6.6 11.1 1.1 8.5 8.1 1.5 2 0 0 2 2 2 0 Trypanosomal VSG domain Coilin_N PF15862.5 ORY26410.1 - 5.3 6.9 12.0 11 5.8 12.0 1.5 1 0 0 1 1 1 0 Coilin N-terminus Peptidase_C37 PF05416.12 ORY26410.1 - 5.4 5.4 4.6 8.3 4.8 4.6 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF4604 PF15377.6 ORY26410.1 - 5.7 7.3 24.6 1.1 9.7 19.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Rer1 PF03248.13 ORY26411.1 - 1.4e-72 243.0 8.2 1.5e-72 242.9 8.2 1.0 1 0 0 1 1 1 1 Rer1 family DUF2718 PF10918.8 ORY26411.1 - 0.18 12.3 0.2 0.18 12.3 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2718) EF-hand_7 PF13499.6 ORY26412.1 - 3.6e-07 30.5 3.2 0.0023 18.3 0.2 4.2 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 ORY26412.1 - 0.0001 22.0 3.4 2.9 8.1 0.0 5.1 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 ORY26412.1 - 0.00038 19.8 1.4 0.71 9.6 0.0 3.8 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 ORY26412.1 - 0.00056 19.3 0.2 0.13 11.8 0.0 2.9 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 ORY26412.1 - 0.013 15.8 0.1 36 4.7 0.0 3.3 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region zf-C2H2 PF00096.26 ORY26413.1 - 2.6e-09 37.0 3.3 0.0004 20.7 0.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY26413.1 - 1.3e-08 34.9 2.1 0.0023 18.6 1.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY26413.1 - 0.00011 22.4 3.9 0.0021 18.4 0.0 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_3rep PF18868.1 ORY26413.1 - 0.0089 16.7 0.1 0.054 14.2 0.0 1.9 1 1 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 ORY26413.1 - 0.037 14.0 1.2 0.98 9.5 0.7 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 ORY26413.1 - 0.098 13.0 1.2 0.26 11.6 1.1 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 ORY26413.1 - 0.14 11.9 3.2 1.7 8.5 2.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.8 ORY26413.1 - 0.62 10.4 3.3 4.2 7.8 1.6 2.6 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PWI PF01480.17 ORY26414.1 - 8.2e-07 29.3 0.0 1.5e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 PWI domain RRM_1 PF00076.22 ORY26414.1 - 8.4e-05 22.3 0.0 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY26414.1 - 0.017 15.1 0.0 0.058 13.4 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 ORY26414.1 - 0.11 12.5 0.1 0.6 10.2 0.0 2.2 3 0 0 3 3 3 0 RNA binding motif PGA2 PF07543.12 ORY26414.1 - 2.5 8.1 5.8 0.46 10.5 1.6 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 MRC1 PF09444.10 ORY26414.1 - 8.8 6.8 13.7 0.13 12.8 4.7 2.2 2 0 0 2 2 2 0 MRC1-like domain FAD_binding_3 PF01494.19 ORY26415.1 - 1e-17 64.5 0.0 7.5e-17 61.6 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain SET PF00856.28 ORY26415.1 - 3.8e-09 37.1 0.0 2.1e-08 34.7 0.0 2.2 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 ORY26415.1 - 0.00092 19.2 3.0 0.031 14.4 0.9 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY26415.1 - 0.0031 17.2 1.7 0.26 11.2 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY26415.1 - 0.006 16.7 0.4 1.6 9.2 0.2 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat SE PF08491.10 ORY26415.1 - 0.025 13.6 0.0 0.11 11.6 0.0 1.9 1 1 0 1 1 1 0 Squalene epoxidase TPR_12 PF13424.6 ORY26415.1 - 0.099 12.9 1.3 9 6.7 0.8 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 ORY26416.1 - 3.3e-17 62.4 8.6 4.1e-17 62.2 8.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY26416.1 - 0.06 12.2 13.9 0.16 10.8 13.9 1.6 1 1 0 1 1 1 0 Sugar (and other) transporter ATG22 PF11700.8 ORY26416.1 - 0.12 11.0 5.0 1.4 7.5 5.0 2.0 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like DUF1774 PF08611.10 ORY26416.1 - 0.61 10.5 2.9 1 9.7 2.3 1.7 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF1774) MFS_1_like PF12832.7 ORY26416.1 - 0.87 8.4 12.8 1.1 8.1 4.2 2.4 1 1 1 2 2 2 0 MFS_1 like family Methyltransf_25 PF13649.6 ORY26418.1 - 1.1e-14 54.9 0.0 2e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY26418.1 - 2.2e-14 54.0 0.0 5.4e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY26418.1 - 5.3e-13 49.1 0.0 8.6e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY26418.1 - 1.4e-12 48.1 0.0 2.5e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY26418.1 - 5e-06 26.4 0.0 7.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY26418.1 - 2.4e-05 23.9 0.0 5.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 ORY26418.1 - 0.002 17.5 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FmrO PF07091.11 ORY26418.1 - 0.01 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) TPMT PF05724.11 ORY26418.1 - 0.023 14.4 0.0 0.067 12.8 0.0 1.8 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DUF3298 PF11738.8 ORY26418.1 - 0.04 14.9 0.6 0.3 12.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3298) CheR PF01739.18 ORY26418.1 - 0.041 13.4 0.0 9.3 5.7 0.0 2.7 2 1 1 3 3 3 0 CheR methyltransferase, SAM binding domain PrmA PF06325.13 ORY26418.1 - 0.068 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_8 PF05148.15 ORY26418.1 - 0.091 12.6 0.0 1.1 9.1 0.0 2.2 1 1 0 1 1 1 0 Hypothetical methyltransferase PRIMA1 PF16101.5 ORY26418.1 - 8.4 6.5 7.1 16 5.5 7.1 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CBS PF00571.28 ORY26419.1 - 2.1e-12 47.3 0.6 0.0013 19.1 0.1 3.5 3 0 0 3 3 3 3 CBS domain SNF2_N PF00176.23 ORY26420.1 - 2.6e-61 207.3 0.0 5e-61 206.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 ORY26420.1 - 2.7e-36 124.0 1.9 2.7e-36 124.0 1.9 2.3 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 ORY26420.1 - 7.1e-20 71.8 0.8 7.1e-20 71.8 0.8 3.0 2 1 0 2 2 2 1 HAND Helicase_C PF00271.31 ORY26420.1 - 5.8e-18 65.3 0.0 2.3e-17 63.3 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY26420.1 - 4e-08 33.4 0.0 2.3e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DBINO PF13892.6 ORY26420.1 - 0.0014 19.0 2.3 0.0014 19.0 2.3 3.2 1 1 1 2 2 2 1 DNA-binding domain DEAD PF00270.29 ORY26420.1 - 0.0018 18.1 0.0 0.0043 16.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 ORY26420.1 - 0.0024 17.1 0.1 0.012 14.7 0.0 2.2 3 0 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 AAA_15 PF13175.6 ORY26420.1 - 9.3 5.8 14.6 0.5 10.0 3.6 2.9 3 0 0 3 3 3 0 AAA ATPase domain Orn_Arg_deC_N PF02784.16 ORY26426.1 - 2.5e-71 239.9 0.0 5.8e-69 232.2 0.0 2.1 1 1 1 2 2 2 2 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 ORY26426.1 - 2.4e-21 75.8 0.0 3.6e-21 75.2 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain LRR_9 PF14580.6 ORY26427.1 - 6.3e-15 55.1 0.3 1e-14 54.4 0.3 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 ORY26427.1 - 2.1e-07 30.6 4.5 2.8e-07 30.2 1.2 2.7 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 ORY26427.1 - 3.1e-06 27.4 7.7 0.00036 20.8 1.4 3.7 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) DUF3966 PF13110.6 ORY26427.1 - 0.11 12.5 0.2 0.25 11.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3966) TIM PF00121.18 ORY26428.1 - 8.1e-90 300.4 0.6 9.4e-90 300.2 0.6 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase Lactamase_B_2 PF12706.7 ORY26429.1 - 2.3e-12 46.9 0.1 4.7e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 ORY26429.1 - 3.2e-11 42.7 0.0 8.5e-11 41.4 0.0 1.8 1 0 0 1 1 1 1 tRNase Z endonuclease Mg_chelatase PF01078.21 ORY26429.1 - 0.023 14.1 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Lactamase_B PF00753.27 ORY26429.1 - 0.033 14.2 0.0 0.091 12.8 0.0 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF2597 PF10772.9 ORY26430.1 - 0.014 15.5 0.1 0.037 14.1 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) BLOC1_2 PF10046.9 ORY26431.1 - 0.11 12.8 0.1 4.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2105 PF09878.9 ORY26432.1 - 0.024 14.4 0.2 0.043 13.5 0.2 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2105) ADH_zinc_N_2 PF13602.6 ORY26433.1 - 4.5e-26 92.5 0.0 9.8e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY26433.1 - 9.9e-18 64.4 1.4 2.2e-17 63.3 1.4 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY26433.1 - 1.4e-09 37.7 0.0 1.9e-08 34.2 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain IstB_IS21 PF01695.17 ORY26433.1 - 0.0025 17.6 0.2 0.0037 17.0 0.2 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein Glu_dehyd_C PF16912.5 ORY26433.1 - 0.0049 16.4 0.8 0.0076 15.8 0.8 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus DapB_N PF01113.20 ORY26433.1 - 0.038 14.1 1.4 0.056 13.6 0.5 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ELFV_dehydrog PF00208.21 ORY26433.1 - 0.044 13.5 4.7 0.13 12.0 3.9 2.0 1 1 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase YtxH PF12732.7 ORY26433.1 - 0.044 14.3 0.2 0.091 13.3 0.2 1.5 1 0 0 1 1 1 0 YtxH-like protein AlaDh_PNT_C PF01262.21 ORY26433.1 - 0.078 12.3 9.2 0.034 13.5 5.4 2.0 1 1 2 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Eno-Rase_NADH_b PF12242.8 ORY26433.1 - 0.15 11.8 1.5 0.32 10.8 1.5 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Homeodomain PF00046.29 ORY26434.1 - 7.2e-15 54.6 0.1 1.5e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY26434.1 - 0.00015 21.6 0.0 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain META PF03724.16 ORY26435.1 - 0.54 10.2 3.3 0.35 10.9 0.4 2.0 2 0 0 2 2 2 0 META domain FHA PF00498.26 ORY26436.1 - 1.2e-16 60.8 0.0 2.3e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 ORY26436.1 - 6e-10 39.3 0.0 1.3e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain dsrm PF00035.26 ORY26436.1 - 1.6e-08 35.1 0.9 5.1e-08 33.5 0.0 2.4 3 0 0 3 3 3 1 Double-stranded RNA binding motif Dicer_dimer PF03368.14 ORY26436.1 - 0.0046 17.1 0.1 0.019 15.1 0.0 2.1 2 0 0 2 2 2 1 Dicer dimerisation domain ADH_N PF08240.12 ORY26438.1 - 1.3e-05 25.0 0.1 0.0017 18.2 0.1 2.3 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain NAD_binding_2 PF03446.15 ORY26442.1 - 1.5e-12 48.0 0.3 2.1e-12 47.5 0.3 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ORY26442.1 - 9.3e-12 45.3 0.2 2.1e-11 44.1 0.0 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase L31 PF09784.9 ORY26443.1 - 2.4e-23 82.5 0.6 2.9e-23 82.2 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 HSP70 PF00012.20 ORY26444.1 - 3e-86 289.9 24.0 1.2e-84 284.7 14.8 2.3 1 1 1 2 2 2 2 Hsp70 protein CDC45 PF02724.14 ORY26444.1 - 0.61 8.3 18.3 1.2 7.4 18.3 1.4 1 0 0 1 1 1 0 CDC45-like protein ESCRT-II PF05871.12 ORY26445.1 - 1.2e-17 64.5 1.1 1.9e-17 63.8 1.1 1.3 1 1 0 1 1 1 1 ESCRT-II complex subunit Methyltransf_PK PF05891.12 ORY26446.1 - 2.8e-58 197.0 0.0 1e-57 195.1 0.0 1.8 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 ORY26446.1 - 0.00018 22.1 0.0 0.00032 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY26446.1 - 0.00048 20.0 0.0 0.00063 19.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY26446.1 - 0.002 18.7 0.0 0.004 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY26446.1 - 0.044 13.6 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DNA_pol_phi PF04931.13 ORY26447.1 - 1.6e-155 519.3 38.9 4.9e-131 438.3 32.4 2.8 1 1 1 2 2 2 2 DNA polymerase phi Nop14 PF04147.12 ORY26447.1 - 1.2e-05 23.8 16.3 2.3e-05 22.8 16.3 1.5 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 ORY26447.1 - 3.6e-05 23.3 19.9 8.5e-05 22.1 19.9 1.6 1 0 0 1 1 1 1 SDA1 FANCI_S2 PF14676.6 ORY26447.1 - 0.0086 16.4 0.2 0.038 14.3 0.2 2.1 1 0 0 1 1 1 1 FANCI solenoid 2 DUF2115 PF09888.9 ORY26447.1 - 0.047 14.2 0.1 19 5.8 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) CDC45 PF02724.14 ORY26447.1 - 0.24 9.7 16.7 0.46 8.7 16.7 1.4 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 ORY26447.1 - 6.2 6.0 33.8 0.012 14.9 21.2 2.6 3 0 0 3 3 3 0 BUD22 SH3_1 PF00018.28 ORY26448.1 - 1.4e-10 40.6 0.0 2.2e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY26448.1 - 5.5e-08 32.6 0.1 9.9e-08 31.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY26448.1 - 3.2e-07 29.9 0.0 6.8e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain 4HB_MCP_1 PF12729.7 ORY26448.1 - 0.54 9.8 1.6 0.97 8.9 1.6 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF2076 PF09849.9 ORY26448.1 - 0.63 10.0 5.8 0.88 9.6 5.8 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) PRCC PF10253.9 ORY26448.1 - 2.8 8.7 6.9 3.6 8.3 6.9 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF2070 PF09843.9 ORY26448.1 - 3.1 6.0 8.4 3.8 5.7 8.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TFIIA PF03153.13 ORY26448.1 - 5.7 6.8 5.9 6.9 6.5 5.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SH3_1 PF00018.28 ORY26449.1 - 2.8e-09 36.4 0.0 5.3e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY26449.1 - 2.6e-05 23.8 0.0 4.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ORY26449.1 - 0.00048 19.9 0.0 0.0009 19.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain CRIM PF16978.5 ORY26449.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), middle CRIM domain FAP PF07174.11 ORY26449.1 - 1.9 7.8 18.1 2.8 7.3 18.1 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DUF4436 PF14494.6 ORY26450.1 - 1.1e-25 90.3 1.2 1.8e-25 89.7 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) Ribosomal_S12 PF17487.2 ORY26450.1 - 0.081 13.7 0.5 0.081 13.7 0.5 2.5 3 0 0 3 3 3 0 Ribosomal protein S12 HgmA PF04209.13 ORY26451.1 - 4e-205 681.4 0.0 4.5e-205 681.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Methyltransf_12 PF08242.12 ORY26452.1 - 9e-15 55.2 0.0 1.3e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY26452.1 - 1.1e-14 54.5 0.0 1.4e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY26452.1 - 7.5e-14 51.8 0.0 1e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY26452.1 - 8.2e-14 52.0 0.0 1.3e-13 51.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY26452.1 - 2e-13 50.9 0.0 3.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORY26452.1 - 0.00017 21.4 0.0 0.0004 20.2 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 ORY26452.1 - 0.00023 20.2 0.0 0.00033 19.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 ORY26452.1 - 0.00055 19.6 0.0 0.00082 19.0 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 ORY26452.1 - 0.0021 17.4 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 ORY26452.1 - 0.0023 17.5 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 ORY26452.1 - 0.0029 17.6 0.2 0.0067 16.4 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain TehB PF03848.14 ORY26452.1 - 0.0046 16.4 0.0 0.0069 15.8 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.20 ORY26452.1 - 0.0096 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase CheR PF01739.18 ORY26452.1 - 0.017 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain FtsJ PF01728.19 ORY26452.1 - 0.079 13.1 0.0 0.15 12.2 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase BUD22 PF09073.10 ORY26453.1 - 9.1e-28 97.8 43.7 5.5e-08 32.6 2.6 5.1 2 2 3 5 5 5 5 BUD22 RyR PF02026.16 ORY26453.1 - 2.4e-06 27.7 0.4 4.2 7.6 0.0 4.3 4 0 0 4 4 4 4 RyR domain GILT PF03227.16 ORY26453.1 - 0.015 15.6 0.0 7.2 6.9 0.0 2.4 1 1 1 2 2 2 0 Gamma interferon inducible lysosomal thiol reductase (GILT) BRCT_3 PF18428.1 ORY26453.1 - 0.09 12.9 0.1 8.1 6.6 0.0 2.2 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain YpzG PF14139.6 ORY26453.1 - 0.17 12.1 9.1 9.8 6.4 0.1 4.3 4 0 0 4 4 4 0 YpzG-like protein Ribosomal_S2 PF00318.20 ORY26454.1 - 4.5e-27 94.7 0.5 1.6e-12 47.1 0.1 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 ORY26454.1 - 0.0088 17.4 4.7 0.025 15.9 4.7 1.8 1 1 0 1 1 1 1 40S ribosomal protein SA C-terminus PGK PF00162.19 ORY26455.1 - 2.4e-152 507.3 1.4 2.7e-152 507.1 1.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase CBM_5_12_2 PF14600.6 ORY26456.1 - 0.00037 20.4 4.4 0.00037 20.4 4.4 1.7 2 0 0 2 2 2 1 Cellulose-binding domain CBM_5_12 PF02839.14 ORY26456.1 - 0.1 13.2 4.8 0.1 13.2 4.8 2.8 3 1 0 3 3 3 0 Carbohydrate binding domain eIF-5a PF01287.20 ORY26458.1 - 1.3e-28 98.9 0.5 1.9e-28 98.3 0.5 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 ORY26458.1 - 0.039 14.0 0.1 0.11 12.5 0.1 1.7 2 0 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain DUF3671 PF12420.8 ORY26459.1 - 0.04 14.0 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function Dicty_REP PF05086.12 ORY26459.1 - 6.1 4.7 11.3 8 4.3 11.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Beta-lactamase PF00144.24 ORY26460.1 - 8e-10 38.5 0.0 9.2e-10 38.3 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase BING4CT PF08149.11 ORY26568.1 - 4.3e-39 132.2 0.0 2.4e-35 120.2 0.0 3.2 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.32 ORY26568.1 - 1.1e-07 32.4 0.0 0.0079 17.0 0.0 6.2 7 1 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY26568.1 - 4.9e-06 26.8 0.0 4.9 7.5 0.0 5.1 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 ORY26568.1 - 0.00025 20.2 0.0 0.00055 19.1 0.0 1.5 1 1 0 1 1 1 1 Coatomer WD associated region WD40_like PF17005.5 ORY26568.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain SARAF PF06682.12 ORY26619.1 - 0.042 13.5 0.0 0.05 13.3 0.0 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Orf78 PF06024.12 ORY26619.1 - 0.07 13.4 0.0 0.09 13.1 0.0 1.1 1 0 0 1 1 1 0 Orf78 (ac78) DUF1378 PF07125.11 ORY26619.1 - 0.43 10.8 1.8 0.83 9.9 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) F-box-like PF12937.7 ORY26746.1 - 0.0007 19.4 0.2 0.002 18.0 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY26746.1 - 0.00083 19.2 0.7 0.003 17.4 0.4 2.2 2 0 0 2 2 2 1 F-box domain Mito_carr PF00153.27 ORY26747.1 - 1.1e-50 169.5 1.3 2.6e-17 62.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3262 PF11660.8 ORY26747.1 - 0.018 15.4 0.4 0.039 14.3 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) UbiA PF01040.18 ORY26747.1 - 0.11 11.7 3.8 0.6 9.4 1.0 2.1 1 1 1 2 2 2 0 UbiA prenyltransferase family RVT_1 PF00078.27 ORY26748.1 - 0.011 15.3 0.1 0.034 13.7 0.0 1.8 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Lipase_3 PF01764.25 ORY26815.1 - 3.6e-07 30.1 0.0 6.3e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Lipase (class 3) Chlorophyllase2 PF12740.7 ORY26815.1 - 0.0031 16.5 0.0 0.0033 16.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF2974 PF11187.8 ORY26815.1 - 0.037 13.6 0.1 0.067 12.7 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 ORY26815.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 ORY26815.1 - 0.11 12.2 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase PF07224.11 ORY26815.1 - 0.12 11.3 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase HOIP-UBA PF16678.5 ORY26816.1 - 0.00017 21.6 0.3 0.48 10.4 0.1 3.2 3 0 0 3 3 3 3 HOIP UBA domain pair TAP_C PF03943.13 ORY26816.1 - 0.014 15.0 4.2 6.7 6.4 0.1 3.9 3 0 0 3 3 3 0 TAP C-terminal domain LisH_2 PF16045.5 ORY26848.1 - 4.6e-10 38.3 0.0 7.7e-10 37.6 0.0 1.4 1 0 0 1 1 1 1 LisH FOP_dimer PF09398.10 ORY26848.1 - 0.0076 16.5 0.0 0.04 14.2 0.0 2.3 1 0 0 1 1 1 1 FOP N terminal dimerisation domain Adeno_shaft PF00608.17 ORY26849.1 - 0.054 13.3 0.5 0.13 12.1 0.5 1.6 1 1 0 1 1 1 0 Adenoviral fibre protein (repeat/shaft region) Phage_HK97_TLTM PF06120.11 ORY26850.1 - 0.039 13.2 0.3 0.04 13.1 0.3 1.0 1 0 0 1 1 1 0 Tail length tape measure protein Glyco_hydro_52 PF03512.13 ORY26850.1 - 0.1 11.5 0.4 0.11 11.5 0.4 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 52 LRR_9 PF14580.6 ORY26851.1 - 5e-10 39.1 0.1 8.8e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 ORY26851.1 - 3.4e-06 27.3 5.5 0.00085 19.7 0.7 3.3 1 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY26851.1 - 3.6e-06 26.6 7.4 0.00031 20.4 1.2 2.1 1 1 1 2 2 2 2 Leucine rich repeat SURF6 PF04935.12 ORY26851.1 - 0.16 11.8 4.5 0.24 11.2 4.5 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 Pox_RNA_Pol_19 PF05320.12 ORY26853.1 - 0.088 12.8 0.1 0.12 12.4 0.1 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Cation_ATPase_C PF00689.21 ORY26937.1 - 2.9e-39 134.7 4.7 4.1e-39 134.2 4.7 1.2 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY26937.1 - 1.9e-18 67.6 0.1 7e-09 36.3 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY26937.1 - 3.4e-15 55.9 0.0 7.9e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY26937.1 - 1.4e-05 24.9 0.5 0.00014 21.7 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY26937.1 - 0.0056 17.1 0.1 0.48 10.8 0.0 2.7 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase TPR_12 PF13424.6 ORY27051.1 - 4.6e-39 132.6 10.6 1.1e-14 54.5 1.0 5.5 2 1 4 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 ORY27051.1 - 7.7e-38 127.3 5.2 1.9e-09 37.1 0.0 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 ORY27051.1 - 2.2e-08 33.7 11.4 0.091 13.0 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORY27051.1 - 7e-07 28.8 8.6 0.027 14.3 0.1 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY27051.1 - 5.3e-06 26.1 13.1 0.15 12.3 0.1 5.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY27051.1 - 0.00017 21.1 1.4 0.0012 18.3 1.4 2.0 1 1 0 1 1 1 1 MalT-like TPR region TPR_14 PF13428.6 ORY27051.1 - 0.00066 20.3 3.5 0.78 10.7 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY27051.1 - 0.0029 18.1 13.3 0.083 13.6 0.3 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY27051.1 - 0.0057 16.6 7.0 0.74 10.0 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY27051.1 - 0.015 15.8 11.1 1.6 9.3 0.2 4.4 3 1 3 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY27051.1 - 0.017 15.4 3.6 0.12 12.6 0.1 3.4 4 1 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 ORY27051.1 - 0.022 15.4 4.2 1.7 9.4 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.9 ORY27051.1 - 0.66 9.7 5.8 20 4.9 0.1 3.9 4 0 0 4 4 4 0 26S proteasome subunit RPN7 Polysacc_deac_1 PF01522.21 ORY27052.1 - 3.4e-11 43.1 0.0 3.7e-11 43.0 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide deacetylase RINGv PF12906.7 ORY27053.1 - 6.9e-12 45.3 7.5 1.5e-11 44.2 7.4 1.6 1 1 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 ORY27053.1 - 0.0053 17.1 6.3 0.0067 16.7 3.3 2.1 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 ORY27053.1 - 0.076 13.2 5.0 0.22 11.7 5.1 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_2 PF13923.6 ORY27054.1 - 0.14 12.0 7.4 0.15 11.9 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3986 PF13143.6 ORY27055.1 - 0.06 14.3 0.4 0.24 12.4 0.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3986) UPA_2 PF17809.1 ORY27055.1 - 0.11 12.3 0.1 0.3 10.9 0.1 1.7 1 0 0 1 1 1 0 UPA domain FlaC_arch PF05377.11 ORY27055.1 - 0.23 11.9 4.7 0.4 11.1 1.1 3.3 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) CENP-H PF05837.12 ORY27055.1 - 0.27 11.7 4.9 0.41 11.1 1.8 3.0 3 0 0 3 3 3 0 Centromere protein H (CENP-H) YabA PF06156.13 ORY27055.1 - 6.8 7.4 7.2 0.83 10.3 0.6 3.0 3 0 0 3 3 3 0 Initiation control protein YabA PBP_like_2 PF12849.7 ORY27056.1 - 0.00059 19.6 0.1 0.0007 19.4 0.1 1.1 1 0 0 1 1 1 1 PBP superfamily domain DUF5033 PF16436.5 ORY27058.1 - 0.03 14.3 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5033) MASE4 PF17158.4 ORY27058.1 - 0.059 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Membrane-associated sensor, integral membrane domain PRANC PF09372.10 ORY27060.1 - 0.15 12.4 1.3 0.26 11.6 0.1 2.0 2 0 0 2 2 2 0 PRANC domain ZT_dimer PF16916.5 ORY27157.1 - 0.0085 16.2 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Shugoshin_N PF07558.11 ORY27251.1 - 0.0013 18.5 1.0 0.094 12.6 0.1 2.5 1 1 1 2 2 2 2 Shugoshin N-terminal coiled-coil region NRBF2 PF08961.10 ORY27251.1 - 0.0022 17.7 0.1 0.0037 16.9 0.1 1.4 1 0 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator YabA PF06156.13 ORY27251.1 - 0.0076 16.9 0.2 0.013 16.1 0.2 1.3 1 0 0 1 1 1 1 Initiation control protein YabA Lebercilin PF15619.6 ORY27251.1 - 0.027 14.1 0.6 0.042 13.5 0.6 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease CEP209_CC5 PF16574.5 ORY27251.1 - 0.042 14.0 0.2 0.064 13.4 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 DivIC PF04977.15 ORY27251.1 - 0.042 13.6 1.3 0.074 12.8 1.1 1.5 1 1 0 1 1 1 0 Septum formation initiator ZapB PF06005.12 ORY27251.1 - 0.11 12.9 0.2 0.21 12.1 0.2 1.4 1 0 0 1 1 1 0 Cell division protein ZapB TFIIE-A_C PF11521.8 ORY27252.1 - 6.1 7.2 10.9 1.6 9.1 6.8 2.0 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha RRM_1 PF00076.22 ORY27255.1 - 2.8e-14 52.7 0.0 3.1e-12 46.1 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPX2_importin PF12214.8 ORY27255.1 - 0.066 13.4 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Cell cycle regulated microtubule associated protein DUF5477 PF17571.2 ORY27258.1 - 0.059 13.5 0.5 0.12 12.5 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5477) XRCC1_N PF01834.16 ORY27264.1 - 0.079 13.0 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 XRCC1 N terminal domain DUF2093 PF09866.9 ORY27266.1 - 0.18 11.3 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2093) RRM_1 PF00076.22 ORY27267.1 - 4.7e-24 84.0 0.0 2.4e-11 43.3 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4573 PF15140.6 ORY27267.1 - 4e-09 36.5 15.5 0.00045 20.1 10.3 4.0 1 1 2 4 4 4 2 Domain of unknown function (DUF4573) RRM_5 PF13893.6 ORY27267.1 - 6.9e-05 22.4 0.0 0.12 12.0 0.0 2.6 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NifU_N PF01592.16 ORY27267.1 - 0.067 13.3 0.4 0.5 10.5 0.0 2.3 2 0 0 2 2 2 0 NifU-like N terminal domain Amelogenin PF02948.15 ORY27267.1 - 2.3 8.8 14.9 3.8 8.1 9.6 3.4 3 2 1 4 4 4 0 Amelogenin WxL PF13731.6 ORY27267.1 - 5 7.1 7.7 9.2 6.2 1.1 2.9 2 0 0 2 2 2 0 WxL domain surface cell wall-binding BaffR-Tall_bind PF09256.10 ORY27268.1 - 1.6e-07 31.0 11.6 5.8 6.8 0.0 10.1 9 0 0 9 9 9 7 BAFF-R, TALL-1 binding MR_MLE_C PF13378.6 ORY27268.1 - 0.0089 15.6 3.3 84 2.6 0.0 8.0 7 4 1 8 8 8 1 Enolase C-terminal domain-like Shugoshin_N PF07558.11 ORY27273.1 - 0.0022 17.8 3.0 0.08 12.8 0.1 3.0 2 1 1 3 3 3 2 Shugoshin N-terminal coiled-coil region NRBF2 PF08961.10 ORY27273.1 - 0.0034 17.0 4.1 0.0089 15.7 4.0 1.8 1 1 0 1 1 1 1 Nuclear receptor-binding factor 2, autophagy regulator FAM76 PF16046.5 ORY27273.1 - 0.0051 16.2 0.3 0.0071 15.7 0.3 1.2 1 0 0 1 1 1 1 FAM76 protein Lebercilin PF15619.6 ORY27273.1 - 0.01 15.5 1.0 0.01 15.5 1.0 2.0 1 1 1 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease MAD PF05557.13 ORY27273.1 - 0.021 13.2 7.7 0.028 12.8 7.7 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein YabA PF06156.13 ORY27273.1 - 0.026 15.1 4.3 0.068 13.8 3.2 2.0 1 1 1 2 2 2 0 Initiation control protein YabA CEP209_CC5 PF16574.5 ORY27273.1 - 0.033 14.4 0.6 0.033 14.4 0.6 2.1 1 1 1 2 2 2 0 Coiled-coil region of centrosome protein CE290 GAS PF13851.6 ORY27273.1 - 0.061 12.7 4.5 0.09 12.1 4.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.15 ORY27273.1 - 0.07 12.9 8.9 0.055 13.3 2.1 2.7 1 1 2 3 3 3 0 Septum formation initiator DUF3828 PF12883.7 ORY27273.1 - 0.13 12.6 0.3 0.68 10.3 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3828) TSC22 PF01166.18 ORY27273.1 - 0.35 11.2 2.1 2.7 8.4 0.6 2.8 1 1 1 2 2 2 0 TSC-22/dip/bun family Cnn_1N PF07989.11 ORY27273.1 - 0.4 10.9 3.5 0.45 10.7 0.8 2.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 ORY27273.1 - 1.5 9.4 9.1 52 4.4 9.1 2.3 1 1 0 1 1 1 0 Cell division protein ZapB SlyX PF04102.12 ORY27273.1 - 7.6 7.2 9.4 2.8 8.6 2.6 2.6 1 1 1 2 2 2 0 SlyX DNA_pol_B_exo1 PF03104.19 ORY27277.1 - 9.6e-26 90.7 0.1 2.2e-25 89.5 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 ORY27277.1 - 1.7e-18 66.6 6.0 7.2e-12 44.8 0.1 3.4 2 1 2 4 4 4 3 DNA polymerase family B zf-C4pol PF14260.6 ORY27277.1 - 4.6e-17 62.2 7.3 8.8e-17 61.3 7.3 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.6 ORY27277.1 - 0.00043 20.3 0.9 0.041 13.9 0.9 2.5 1 1 0 1 1 1 1 RNase_H superfamily RRM_1 PF00076.22 ORY27278.1 - 5.5e-14 51.7 0.1 2e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY27278.1 - 0.031 13.9 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TIM21 PF08294.11 ORY27278.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 TIM21 Herpes_U44 PF04533.13 ORY27280.1 - 0.2 11.3 0.0 0.2 11.2 0.0 1.0 1 0 0 1 1 1 0 Herpes virus U44 protein Amidase PF01425.21 ORY27283.1 - 0.0063 15.5 0.4 0.0072 15.3 0.4 1.0 1 0 0 1 1 1 1 Amidase DUF1262 PF06880.11 ORY27283.1 - 0.089 13.2 0.1 0.11 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1262) DNA_pol_B_exo1 PF03104.19 ORY27284.1 - 3.8e-27 95.3 0.0 8.8e-27 94.1 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 ORY27284.1 - 4.4e-23 81.7 6.1 8.2e-11 41.3 0.1 3.4 2 1 2 4 4 4 3 DNA polymerase family B zf-C4pol PF14260.6 ORY27284.1 - 4.4e-17 62.3 7.3 8.6e-17 61.4 7.3 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.6 ORY27284.1 - 0.0039 17.2 0.7 0.06 13.3 0.7 2.3 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.9 ORY27284.1 - 0.031 14.0 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RRM_1 PF00076.22 ORY27285.1 - 5.6e-14 51.7 0.1 2e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY27285.1 - 0.016 14.8 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TIM21 PF08294.11 ORY27285.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 TIM21 Herpes_U44 PF04533.13 ORY27287.1 - 0.04 13.5 0.0 1.3 8.6 0.0 2.0 2 0 0 2 2 2 0 Herpes virus U44 protein DIMCO_N PF16844.5 ORY27287.1 - 0.045 14.1 0.1 1.6 9.1 0.0 2.1 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Helicase_C PF00271.31 ORY27292.1 - 0.073 13.4 0.1 0.13 12.6 0.1 1.5 1 1 0 1 1 1 0 Helicase conserved C-terminal domain RRM_1 PF00076.22 ORY27303.1 - 6.5e-15 54.7 0.0 1.3e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4573 PF15140.6 ORY27303.1 - 9e-07 28.9 12.5 6.3e-05 22.8 9.1 3.3 1 1 0 2 2 2 2 Domain of unknown function (DUF4573) Amelogenin PF02948.15 ORY27303.1 - 0.88 10.2 9.1 6.9 7.3 8.3 2.5 2 1 0 2 2 2 0 Amelogenin zf-C4pol PF14260.6 ORY27307.1 - 1.1e-14 54.6 5.0 1.1e-14 54.6 5.0 2.2 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B PF00136.21 ORY27307.1 - 1.5e-10 40.4 0.1 6.4e-09 35.0 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase family B NinF PF05810.12 ORY27307.1 - 0.046 13.6 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 NinF protein TEX12 PF15219.6 ORY27307.1 - 0.046 14.0 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Testis-expressed 12 zf-ACC PF17848.1 ORY27307.1 - 0.23 11.6 0.2 0.23 11.6 0.2 2.6 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain DZR PF12773.7 ORY27307.1 - 0.36 10.9 8.9 3.7 7.7 1.4 3.0 2 1 1 3 3 3 0 Double zinc ribbon RRM_1 PF00076.22 ORY27308.1 - 2e-14 53.2 0.0 3.7e-13 49.1 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPX2_importin PF12214.8 ORY27308.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Cell cycle regulated microtubule associated protein L_protein_N PF15518.6 ORY27309.1 - 0.014 15.2 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 L protein N-terminus Retrotran_gag_2 PF14223.6 ORY27428.1 - 0.00013 21.6 0.3 0.00028 20.6 0.1 1.6 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type FlaF PF07309.11 ORY27428.1 - 0.018 15.1 0.0 0.041 13.9 0.0 1.6 1 0 0 1 1 1 0 Flagellar protein FlaF Retrotrans_gag PF03732.17 ORY27428.1 - 0.022 15.0 0.0 0.045 14.0 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_5 PF14787.6 ORY27428.1 - 0.1 12.3 3.8 0.24 11.1 3.8 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 ORY27428.1 - 0.43 10.5 3.9 0.68 9.8 3.9 1.3 1 0 0 1 1 1 0 Zinc knuckle MHB PF16525.5 ORY27428.1 - 0.66 10.3 4.0 1.7 9.0 0.3 2.6 2 0 0 2 2 2 0 Haemophore, haem-binding HU-CCDC81_euk_2 PF18289.1 ORY27550.1 - 3.4e-21 75.2 0.0 1.7e-18 66.5 0.0 2.2 2 0 0 2 2 2 2 CCDC81 eukaryotic HU domain 2 HU-CCDC81_euk_1 PF14908.6 ORY27550.1 - 2.8e-07 30.6 0.0 4.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-HIG PF18291.1 ORY27550.1 - 0.031 14.4 0.0 7.8 6.6 0.0 2.6 2 1 1 3 3 3 0 HU domain fused to wHTH, Ig, or Glycine-rich motif US2 PF02476.15 ORY27550.1 - 0.036 14.8 0.0 0.91 10.2 0.0 2.2 2 0 0 2 2 2 0 US2 family Bac_DNA_binding PF00216.21 ORY27550.1 - 0.053 13.7 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial DNA-binding protein HU-CCDC81_bac_2 PF18175.1 ORY27550.1 - 0.15 12.0 0.0 0.6 10.0 0.0 1.8 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 BTB PF00651.31 ORY27551.1 - 6.1e-06 26.4 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain RibD_C PF01872.17 ORY27552.1 - 7.2e-09 35.8 0.0 2.5e-08 34.0 0.0 1.9 1 1 0 1 1 1 1 RibD C-terminal domain DDT PF02791.17 ORY27554.1 - 0.00026 21.2 0.7 0.00046 20.4 0.7 1.4 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 ORY27554.1 - 0.052 13.1 0.0 0.17 11.4 0.0 1.9 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 ScsC_N PF18312.1 ORY27555.1 - 0.044 13.6 0.4 0.091 12.6 0.4 1.5 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain DUF1548 PF07579.11 ORY27556.1 - 0.1 12.9 0.1 11 6.3 0.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1548) DUF2284 PF10050.9 ORY27556.1 - 0.58 9.9 2.3 0.91 9.2 0.7 2.0 1 1 1 2 2 2 0 Predicted metal-binding protein (DUF2284) LPP PF04728.13 ORY27556.1 - 0.83 10.1 6.4 0.39 11.1 3.3 2.2 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF1604 PF07713.13 ORY27556.1 - 3.1 7.7 5.8 0.89 9.4 0.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1604) adh_short_C2 PF13561.6 ORY27557.1 - 0.027 14.0 0.0 0.029 13.9 0.0 1.0 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase DUF4394 PF14339.6 ORY27558.1 - 0.15 11.4 0.0 0.61 9.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4394) DDT PF02791.17 ORY27559.1 - 0.00026 21.2 0.7 0.00047 20.4 0.7 1.4 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 ORY27559.1 - 0.045 13.3 0.0 0.18 11.4 0.0 2.1 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 ScsC_N PF18312.1 ORY27560.1 - 0.043 13.6 0.4 0.091 12.6 0.4 1.6 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain LPP PF04728.13 ORY27561.1 - 0.12 12.8 3.2 0.52 10.7 3.2 2.1 1 0 0 1 1 1 0 Lipoprotein leucine-zipper PHD PF00628.29 ORY27563.1 - 1e-06 28.5 5.6 2.2e-06 27.4 5.6 1.6 1 0 0 1 1 1 1 PHD-finger DDT PF02791.17 ORY27563.1 - 0.00037 20.7 0.7 0.00071 19.8 0.7 1.4 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 ORY27563.1 - 0.092 12.3 0.0 0.26 10.9 0.0 1.8 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 PHD_Oberon PF07227.11 ORY27563.1 - 0.22 11.4 2.4 0.41 10.5 2.4 1.3 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein HALZ PF02183.18 ORY27564.1 - 0.019 15.2 0.8 0.036 14.3 0.8 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DivIC PF04977.15 ORY27564.1 - 0.47 10.3 2.8 0.56 10.0 0.2 2.0 2 0 0 2 2 2 0 Septum formation initiator bZIP_2 PF07716.15 ORY27564.1 - 0.81 9.8 9.4 0.12 12.5 2.0 2.2 2 0 0 2 2 2 0 Basic region leucine zipper ZapB PF06005.12 ORY27564.1 - 4.2 7.9 10.3 32 5.0 10.3 2.2 1 1 0 1 1 1 0 Cell division protein ZapB TPR_MLP1_2 PF07926.12 ORY27566.1 - 0.0042 17.1 1.1 0.0069 16.5 1.1 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Sec2p PF06428.11 ORY27566.1 - 0.02 14.8 3.5 0.044 13.8 3.5 1.5 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF4138 PF13595.6 ORY27566.1 - 0.048 12.9 0.1 0.061 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4138) DUF334 PF03904.13 ORY27566.1 - 0.055 13.0 0.8 0.07 12.7 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Gon7 PF08738.10 ORY27566.1 - 0.077 13.1 5.4 0.038 14.1 3.2 1.5 1 1 1 2 2 2 0 Gon7 family DUF4140 PF13600.6 ORY27566.1 - 0.093 13.2 0.3 0.16 12.4 0.3 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) SOG2 PF10428.9 ORY27566.1 - 0.26 10.4 12.7 0.31 10.2 12.7 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Chibby PF14645.6 ORY27566.1 - 2.7 8.4 7.7 21 5.6 7.7 2.1 1 1 0 1 1 1 0 Chibby family Snapin_Pallidin PF14712.6 ORY27567.1 - 0.0055 17.1 1.7 0.0055 17.1 1.7 2.2 2 0 0 2 2 2 1 Snapin/Pallidin Mito_fiss_reg PF05308.11 ORY27569.1 - 1.1 9.2 3.6 1.3 9.1 3.6 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Angiomotin_C PF12240.8 ORY27570.1 - 0.016 14.8 0.2 0.02 14.5 0.2 1.3 1 0 0 1 1 1 0 Angiomotin C terminal TMF_TATA_bd PF12325.8 ORY27570.1 - 0.081 13.2 0.3 0.13 12.5 0.3 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CLZ PF16526.5 ORY27570.1 - 0.15 12.4 0.3 0.29 11.5 0.3 1.4 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ATG16 PF08614.11 ORY27570.1 - 1.2 9.3 4.7 2.5 8.3 4.7 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TPR_10 PF13374.6 ORY27572.1 - 2.9e-40 135.1 1.0 3.5e-07 29.9 0.0 6.2 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 ORY27572.1 - 1.2e-38 131.2 0.5 5.1e-11 42.7 0.0 4.4 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY27572.1 - 9.2e-09 35.1 1.8 1.4e-05 24.7 0.1 2.3 1 1 1 2 2 2 2 MalT-like TPR region TPR_1 PF00515.28 ORY27572.1 - 2.6e-08 33.3 1.8 0.52 10.2 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY27572.1 - 3.3e-08 33.0 4.6 1.1 9.5 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY27572.1 - 6.8e-08 32.1 8.6 0.15 12.4 0.4 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY27572.1 - 1.9e-07 30.6 4.7 0.1 12.7 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY27572.1 - 0.00023 21.6 2.0 2.8 8.5 0.1 3.9 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY27572.1 - 0.00025 21.2 0.3 27 5.5 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY27572.1 - 0.00038 20.9 4.5 0.58 10.9 0.2 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY27572.1 - 0.00079 20.0 2.7 31 5.7 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.20 ORY27572.1 - 0.0088 16.2 8.0 0.76 10.2 0.0 5.3 5 2 0 5 5 4 1 PPR repeat TPR_16 PF13432.6 ORY27572.1 - 0.009 16.6 0.3 15 6.4 0.0 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 ORY27572.1 - 0.042 14.2 0.3 17 5.8 0.0 3.7 2 1 3 5 5 5 0 Tetratricopeptide repeat ssDBP_DBD PF18361.1 ORY27572.1 - 0.055 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Single stranded DNA-binding protein ss DNA binding domain DUF2225 PF09986.9 ORY27572.1 - 0.056 13.2 2.2 1 9.0 1.1 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Spectrin_like PF18373.1 ORY27572.1 - 0.059 13.4 0.5 0.23 11.5 0.1 2.3 2 0 0 2 2 2 0 Spectrin like domain PPR_2 PF13041.6 ORY27572.1 - 0.07 13.3 0.0 19 5.5 0.0 3.0 2 0 0 2 2 2 0 PPR repeat family Erf4 PF10256.9 ORY27572.1 - 0.094 12.8 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family NUDE_C PF04880.13 ORY27573.1 - 0.0017 18.9 0.4 0.0028 18.2 0.4 1.5 1 0 0 1 1 1 1 NUDE protein, C-terminal conserved region Spc24 PF08286.11 ORY27573.1 - 3 8.1 6.1 4.2 7.7 6.1 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Sulfotransfer_3 PF13469.6 ORY27574.1 - 7.1e-36 124.6 0.0 6.9e-35 121.4 0.0 2.4 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 ORY27574.1 - 1.8e-07 30.9 0.2 4.4e-07 29.7 0.2 1.6 1 1 0 1 1 1 1 Sulfotransferase domain Sulphotransf PF09037.10 ORY27574.1 - 0.015 14.8 0.1 0.31 10.6 0.0 2.2 2 0 0 2 2 2 0 Stf0 sulphotransferase Sulfotransfer_4 PF17784.1 ORY27574.1 - 0.071 12.9 0.4 0.46 10.3 0.0 2.2 2 1 0 3 3 3 0 Sulfotransferase domain Focal_AT PF03623.13 ORY27574.1 - 0.072 13.1 0.2 9.3 6.3 0.0 2.5 2 0 0 2 2 2 0 Focal adhesion targeting region UQ_con PF00179.26 ORY27575.1 - 5.3e-20 71.5 0.0 6.9e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY27575.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B SNAP PF14938.6 ORY27576.1 - 4.3e-26 92.0 3.3 5.7e-26 91.6 3.3 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 ORY27576.1 - 0.0012 19.1 5.4 6.7 7.1 0.3 3.9 2 1 1 3 3 3 3 Tetratricopeptide repeat DUF1203 PF06718.11 ORY27576.1 - 0.076 13.3 0.1 0.7 10.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1203) MIT PF04212.18 ORY27576.1 - 0.42 10.7 3.5 2.2 8.4 0.1 3.0 1 1 2 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 ORY27576.1 - 0.8 10.5 7.8 3.6 8.4 0.0 4.8 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY27576.1 - 7.5 6.9 9.7 8.3 6.8 0.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_16 PF00722.21 ORY27577.1 - 5.9e-30 104.0 0.1 8.9e-30 103.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 ORY27577.1 - 2.1e-11 42.9 1.6 6.2e-05 21.6 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) ABC_tran PF00005.27 ORY27578.1 - 2.4e-19 70.2 0.0 1e-18 68.2 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 ORY27578.1 - 2.2e-11 44.1 0.2 2.6e-08 34.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 ORY27578.1 - 2.8e-06 26.7 27.3 2.8e-06 26.7 27.3 3.1 2 2 0 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.19 ORY27578.1 - 0.00041 19.9 0.0 0.00094 18.7 0.0 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 ORY27578.1 - 0.04 14.1 0.0 0.41 10.9 0.0 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 ORY27578.1 - 0.057 13.1 0.0 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain FtsX PF02687.21 ORY27578.1 - 9.9 6.7 16.9 7.8 7.0 10.4 3.3 3 0 0 3 3 3 0 FtsX-like permease family MoaE PF02391.17 ORY27579.1 - 9.1e-36 122.6 0.1 1.8e-35 121.7 0.1 1.4 1 0 0 1 1 1 1 MoaE protein ABC_tran PF00005.27 ORY27579.1 - 1.8e-17 64.2 0.0 7.9e-16 58.8 0.0 2.9 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 ORY27579.1 - 3.3e-13 50.1 0.0 1.1e-09 38.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 ORY27579.1 - 1.6e-12 47.2 29.8 1.6e-12 47.2 29.8 2.0 2 0 0 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.19 ORY27579.1 - 0.029 13.8 0.0 0.051 13.0 0.0 1.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 ORY27579.1 - 0.23 11.1 0.0 2.5 7.7 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain m04gp34like PF12216.8 ORY27580.1 - 0.036 13.6 0.3 0.19 11.2 0.1 2.1 2 0 0 2 2 2 0 Immune evasion protein Ribosomal_L5e PF17144.4 ORY27581.1 - 1.2e-69 233.5 1.8 1.2e-69 233.5 1.8 2.5 2 1 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 ORY27581.1 - 1.4e-29 102.9 9.9 1.4e-29 102.9 9.9 2.1 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Erf4 PF10256.9 ORY27581.1 - 0.16 12.1 0.0 0.64 10.1 0.0 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family Gtr1_RagA PF04670.12 ORY27583.1 - 0.064 12.6 0.0 0.069 12.5 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Nucleos_tra2_C PF07662.13 ORY27585.1 - 9e-61 205.3 3.2 9e-61 205.3 3.2 2.1 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ORY27585.1 - 1.5e-19 70.3 4.9 1.5e-19 70.3 4.9 3.2 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 ORY27585.1 - 7.5e-05 23.0 7.8 7.5e-05 23.0 7.8 3.9 3 1 1 4 4 4 1 Nucleoside recognition Nucleos_tra2_C PF07662.13 ORY27586.1 - 5.4e-59 199.5 7.2 5.4e-59 199.5 7.2 1.9 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ORY27586.1 - 5.7e-20 71.7 5.4 5.7e-20 71.7 5.4 2.9 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 ORY27586.1 - 1.3e-05 25.4 6.5 1.3e-05 25.4 6.5 3.5 3 0 0 3 3 3 1 Nucleoside recognition ADH_zinc_N PF00107.26 ORY27587.1 - 3.6e-23 82.0 0.3 5.4e-23 81.4 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY27587.1 - 2.3e-13 50.0 0.6 4.3e-13 49.1 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ORY27587.1 - 2.2e-08 35.2 0.0 4e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NMT1 PF09084.11 ORY27588.1 - 5.9e-76 255.2 0.0 7.1e-76 254.9 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 ORY27588.1 - 8e-06 25.7 0.0 0.19 11.4 0.0 2.7 3 0 0 3 3 3 2 NMT1-like family Ank_2 PF12796.7 ORY27589.1 - 3.1e-22 78.9 0.5 1.8e-10 41.3 0.0 3.7 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY27589.1 - 3.2e-13 49.9 1.4 0.0049 17.4 0.0 5.5 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY27589.1 - 1.9e-10 40.1 0.3 1.3 9.8 0.0 7.0 7 1 1 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 ORY27589.1 - 8.4e-08 32.3 4.8 0.68 10.3 0.1 5.6 1 1 5 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY27589.1 - 0.00074 19.9 7.4 50 4.6 0.0 7.2 7 1 1 8 8 8 0 Ankyrin repeat DUF3447 PF11929.8 ORY27589.1 - 0.12 12.3 1.9 3.3 7.7 0.4 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) LRR_8 PF13855.6 ORY27590.1 - 3.7e-14 52.2 7.3 2.1e-06 27.4 1.0 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY27590.1 - 4.5e-08 33.3 10.1 0.055 13.9 0.1 5.2 2 1 5 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY27590.1 - 0.00019 21.5 7.8 16 6.6 0.0 6.6 7 1 1 8 8 8 2 Leucine Rich Repeat DUF599 PF04654.12 ORY27591.1 - 3.8 6.9 6.3 0.5 9.7 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF599 ApoO PF09769.9 ORY27592.1 - 1.8e-17 63.5 0.2 1.5e-16 60.5 0.1 1.9 1 1 1 2 2 2 1 Apolipoprotein O Beta-lactamase PF00144.24 ORY27593.1 - 2.1e-30 106.1 0.1 2e-29 102.9 0.1 2.0 1 1 0 1 1 1 1 Beta-lactamase Beta-lactamase PF00144.24 ORY27594.1 - 2.5e-35 122.3 0.0 1.9e-34 119.4 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase Form-deh_trans PF09163.11 ORY27594.1 - 0.0028 17.4 1.3 0.2 11.5 0.5 3.1 3 0 0 3 3 3 1 Formate dehydrogenase N, transmembrane LCIB_C_CA PF18599.1 ORY27594.1 - 0.19 11.0 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Ank_2 PF12796.7 ORY27595.1 - 4.8e-60 200.1 2.7 2.6e-11 43.9 0.0 6.4 1 1 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY27595.1 - 7.2e-29 99.5 4.4 0.039 14.3 0.0 11.0 4 3 9 13 13 13 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY27595.1 - 6.4e-27 93.6 4.3 8.4e-06 26.2 0.0 8.2 6 2 3 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY27595.1 - 1.7e-25 86.3 3.8 0.087 13.4 0.1 11.2 11 1 1 12 12 12 8 Ankyrin repeat Ank PF00023.30 ORY27595.1 - 2.8e-14 52.8 5.5 0.08 13.4 0.1 9.5 9 2 1 10 10 10 3 Ankyrin repeat MiaE_2 PF13794.6 ORY27595.1 - 0.042 13.6 0.0 13 5.4 0.0 3.2 2 2 1 3 3 3 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like tRNA-synt_His PF13393.6 ORY27595.1 - 0.1 11.8 0.0 1.6 7.9 0.0 2.5 2 0 0 2 2 2 0 Histidyl-tRNA synthetase Neur PF00064.18 ORY27596.1 - 0.029 13.1 0.0 0.038 12.8 0.0 1.1 1 0 0 1 1 1 0 Neuraminidase Cg6151-P PF10233.9 ORY27597.1 - 0.00019 21.7 4.6 0.00019 21.7 4.6 2.3 2 1 1 3 3 3 1 Uncharacterized conserved protein CG6151-P SPC25 PF06703.11 ORY27597.1 - 0.042 13.6 0.2 0.042 13.6 0.2 2.0 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF4389 PF14333.6 ORY27597.1 - 0.43 10.5 0.1 0.43 10.5 0.1 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF4389) LMF1 PF06762.14 ORY27597.1 - 0.61 9.1 7.1 0.83 8.7 6.0 1.9 1 1 0 1 1 1 0 Lipase maturation factor PDR_CDR PF06422.12 ORY27597.1 - 1.4 8.8 4.4 1.7 8.6 1.2 2.5 2 0 0 2 2 2 0 CDR ABC transporter DUF2106 PF09879.9 ORY27598.1 - 0.003 17.1 0.2 0.0072 15.9 0.2 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2106) Tetraspanin PF00335.20 ORY27598.1 - 0.5 10.0 12.1 0.068 12.9 4.6 2.2 2 0 0 2 2 2 0 Tetraspanin family PfkB PF00294.24 ORY27599.1 - 1e-07 31.6 0.0 1.1e-07 31.4 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 ORY27599.1 - 0.0059 16.0 0.0 0.0064 15.9 0.0 1.0 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Glyco_trans_2_3 PF13632.6 ORY27600.1 - 1.9e-28 99.7 4.5 1.9e-28 99.7 4.5 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY27600.1 - 2e-16 60.6 0.0 2.8e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ORY27600.1 - 0.0015 18.1 0.0 0.11 12.0 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 21 ABC2_membrane_5 PF13346.6 ORY27601.1 - 0.52 9.8 3.1 0.4 10.2 1.5 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein JAB PF01398.21 ORY27602.1 - 3.9e-30 104.3 0.3 6.3e-30 103.6 0.3 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 ORY27602.1 - 4.3e-20 72.4 0.0 9.8e-20 71.3 0.0 1.6 2 0 0 2 2 2 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 ORY27602.1 - 0.002 17.9 0.0 0.0044 16.8 0.0 1.6 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 ORY27602.1 - 0.076 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) UQ_con PF00179.26 ORY27603.1 - 2.4e-13 49.9 0.0 2.4e-13 49.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Glyco_transf_20 PF00982.21 ORY27605.1 - 4.6e-177 589.4 0.0 5.6e-177 589.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 ORY27605.1 - 2.1e-48 164.5 0.0 5.4e-33 114.1 0.0 2.2 2 0 0 2 2 2 2 Trehalose-phosphatase Glyco_trans_1_4 PF13692.6 ORY27605.1 - 5.8e-05 23.5 0.0 0.00013 22.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Ribosomal_L11_N PF03946.14 ORY27605.1 - 0.019 14.8 0.1 0.064 13.1 0.1 1.9 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain Glycos_transf_1 PF00534.20 ORY27605.1 - 0.16 11.5 0.4 1.8 8.1 0.1 2.3 2 1 0 2 2 2 0 Glycosyl transferases group 1 Ank_2 PF12796.7 ORY27606.1 - 2.7e-18 66.3 0.2 2e-05 25.1 0.0 3.8 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY27606.1 - 2.2e-11 44.0 1.3 0.12 13.0 0.1 6.3 2 2 6 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY27606.1 - 2.2e-06 27.5 0.5 14 6.7 0.0 7.2 8 0 0 8 8 8 1 Ankyrin repeat Ank PF00023.30 ORY27606.1 - 0.00062 20.1 11.8 35 5.1 0.0 7.8 9 1 0 9 9 9 1 Ankyrin repeat Ank_5 PF13857.6 ORY27606.1 - 0.0037 17.5 1.2 8.1 6.9 0.0 4.2 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Pkinase PF00069.25 ORY27607.1 - 1.3e-45 155.9 0.0 2.5e-45 154.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY27607.1 - 1.9e-25 89.6 0.0 3e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY27607.1 - 5.3e-05 22.2 0.1 0.0001 21.2 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY27607.1 - 0.036 13.4 0.0 0.073 12.4 0.0 1.5 1 0 0 1 1 1 0 Kinase-like PACT_coil_coil PF10495.9 ORY27608.1 - 6e-15 55.6 0.5 2.8e-14 53.4 0.2 2.5 2 0 0 2 2 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Jnk-SapK_ap_N PF09744.9 ORY27608.1 - 0.0049 17.1 11.3 0.0049 17.1 11.3 4.3 1 1 3 4 4 4 1 JNK_SAPK-associated protein-1 PI31_Prot_N PF11566.8 ORY27608.1 - 0.017 14.9 0.2 0.052 13.4 0.2 1.8 1 0 0 1 1 1 0 PI31 proteasome regulator N-terminal RNA_pol_L PF01193.24 ORY27608.1 - 0.053 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain TSC22 PF01166.18 ORY27608.1 - 0.06 13.7 0.1 0.06 13.7 0.1 4.4 6 0 0 6 6 5 0 TSC-22/dip/bun family HTH_6 PF01418.17 ORY27608.1 - 0.083 12.9 0.7 0.26 11.3 0.7 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HAP1_N PF04849.13 ORY27608.1 - 0.35 10.0 44.1 0.044 13.0 7.7 3.5 2 1 2 4 4 4 0 HAP1 N-terminal conserved region Filament PF00038.21 ORY27608.1 - 0.84 9.2 42.2 1.2 8.7 9.4 2.4 1 1 2 3 3 3 0 Intermediate filament protein HALZ PF02183.18 ORY27608.1 - 1.1 9.5 19.1 1.5 9.1 2.0 5.1 5 1 0 5 5 5 0 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.9 ORY27608.1 - 3.5 7.7 50.7 0.54 10.3 15.3 4.5 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GIT_CC PF16559.5 ORY27608.1 - 4.1 7.3 11.6 5.5 6.9 1.7 4.6 4 1 1 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor Golgin_A5 PF09787.9 ORY27609.1 - 0.00073 19.1 1.2 0.00073 19.1 1.2 6.0 3 2 3 6 6 6 3 Golgin subfamily A member 5 Fib_alpha PF08702.10 ORY27609.1 - 0.0057 16.8 6.6 0.0057 16.8 6.6 7.2 4 3 3 7 7 7 4 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 ORY27609.1 - 0.0065 16.5 4.0 0.0065 16.5 4.0 7.7 6 3 4 10 10 10 1 Protein of unknown function (DUF1664) KxDL PF10241.9 ORY27609.1 - 0.062 13.6 0.5 0.062 13.6 0.5 7.1 5 2 2 7 7 7 0 Uncharacterized conserved protein PapC_N PF13954.6 ORY27609.1 - 0.65 10.0 3.7 0.66 10.0 1.1 2.4 2 0 0 2 2 2 0 PapC N-terminal domain PspB PF06667.12 ORY27609.1 - 1.8 8.7 7.3 0.51 10.4 2.5 2.7 2 0 0 2 2 2 0 Phage shock protein B ALIX_LYPXL_bnd PF13949.6 ORY27610.1 - 0.0026 17.1 10.9 0.0026 17.1 10.9 4.2 1 1 3 4 4 4 3 ALIX V-shaped domain binding to HIV IFN-gamma PF00714.17 ORY27610.1 - 0.017 14.9 7.6 3.5 7.5 0.1 5.1 5 1 0 5 5 5 0 Interferon gamma DUF1515 PF07439.11 ORY27610.1 - 4.9 7.2 26.4 0.81 9.7 0.5 6.1 5 2 1 6 6 6 0 Protein of unknown function (DUF1515) WD40 PF00400.32 ORY27611.1 - 5.8e-15 55.4 0.8 0.0033 18.2 0.0 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 ORY27611.1 - 0.0097 15.2 0.1 0.2 10.9 0.0 2.6 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Ribosomal_L14e PF01929.17 ORY27612.1 - 3.5e-31 107.5 4.3 5e-31 107.0 4.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 ORY27612.1 - 5.6e-05 22.9 3.4 0.00013 21.8 3.4 1.7 1 0 0 1 1 1 1 KOW motif ATPgrasp_TupA PF14305.6 ORY27612.1 - 0.039 13.7 0.1 0.047 13.5 0.1 1.2 1 0 0 1 1 1 0 TupA-like ATPgrasp IL3 PF02059.15 ORY27613.1 - 0.056 13.5 0.1 0.092 12.8 0.1 1.4 1 0 0 1 1 1 0 Interleukin-3 Tcp11 PF05794.13 ORY27613.1 - 0.059 12.4 0.6 0.076 12.1 0.6 1.0 1 0 0 1 1 1 0 T-complex protein 11 KAR9 PF08580.10 ORY27613.1 - 0.74 8.3 13.3 0.88 8.0 13.3 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Beta-lactamase PF00144.24 ORY27616.1 - 1.3e-28 100.2 0.0 3.4e-28 98.8 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase Homeodomain PF00046.29 ORY27616.1 - 0.071 13.0 0.1 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Homeodomain ThrE_2 PF12821.7 ORY27720.1 - 9e-06 25.9 13.3 2.2e-05 24.6 13.3 1.6 1 1 0 1 1 1 1 Threonine/Serine exporter, ThrE ThrE PF06738.12 ORY27720.1 - 0.088 12.2 16.6 0.55 9.6 0.0 2.9 2 1 0 2 2 2 0 Putative threonine/serine exporter DUF1525 PF07511.11 ORY27721.1 - 0.088 13.0 0.8 0.23 11.6 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1525) UDPGT PF00201.18 ORY27723.1 - 4.7e-07 29.0 0.0 6.5e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase KDZ PF18758.1 ORY27725.1 - 6e-11 42.4 0.0 9.8e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Pet20 PF08692.10 ORY27725.1 - 0.015 16.0 0.1 0.029 15.1 0.1 1.5 1 1 0 1 1 1 0 Mitochondrial protein Pet20 MULE PF10551.9 ORY27726.1 - 0.0023 18.3 2.0 0.0045 17.4 0.4 2.5 2 1 0 2 2 2 1 MULE transposase domain RNase_H PF00075.24 ORY27727.1 - 2.6e-09 37.4 0.1 7.4e-09 35.9 0.1 1.8 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 ORY27727.1 - 0.0032 18.1 1.2 0.0032 18.1 1.2 2.3 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase tRNA-synt_1f PF01921.18 ORY27730.1 - 0.14 11.0 0.0 0.16 10.8 0.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (K) Spt20 PF12090.8 ORY27731.1 - 0.0037 16.9 4.1 0.0044 16.7 4.1 1.1 1 0 0 1 1 1 1 Spt20 family eIF-3_zeta PF05091.12 ORY27731.1 - 0.017 14.2 1.0 0.019 14.0 1.0 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Lin-8 PF03353.15 ORY27731.1 - 0.045 13.3 1.1 0.059 12.9 1.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF908 PF06012.12 ORY27731.1 - 0.085 12.3 3.5 0.11 11.9 3.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Dicty_REP PF05086.12 ORY27731.1 - 0.2 9.6 1.4 0.23 9.4 1.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Med3 PF11593.8 ORY27731.1 - 0.47 9.6 8.5 0.66 9.1 8.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3292 PF11696.8 ORY27732.1 - 0.055 11.9 8.2 0.067 11.6 8.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Oxidored_q2 PF00420.24 ORY27855.1 - 0.024 14.2 7.2 3.1 7.5 0.0 2.4 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L LRR_8 PF13855.6 ORY27856.1 - 5.5e-10 38.9 2.3 0.021 14.6 0.0 3.7 3 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY27856.1 - 6.1e-10 39.2 10.9 0.12 12.8 1.2 4.6 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY27856.1 - 2.4e-05 24.3 6.0 26 5.9 0.1 6.7 3 2 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 ORY27856.1 - 6.5e-05 22.7 4.7 2.3 8.5 0.0 5.4 5 1 0 5 5 5 2 Leucine Rich repeat Oxysterol_BP PF01237.18 ORY27857.1 - 1.4e-49 168.9 0.2 3.9e-44 151.0 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein Zn_clus PF00172.18 ORY27858.1 - 0.0012 18.9 7.2 0.0023 18.0 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S8 PF00082.22 ORY27859.1 - 5.9e-32 111.1 4.8 8.8e-32 110.6 4.8 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 ORY27859.1 - 2.2e-23 82.1 0.2 4.4e-23 81.1 0.2 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 ORY27859.1 - 0.00016 22.4 0.0 0.00032 21.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 ORY27859.1 - 0.034 14.6 0.2 0.06 13.8 0.2 1.4 1 0 0 1 1 1 0 N-terminal of Subtilase family Mito_carr PF00153.27 ORY27860.1 - 5.3e-55 183.3 6.5 5.1e-18 64.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 ORY27861.1 - 6.7e-70 235.5 0.0 8.2e-70 235.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY27861.1 - 3e-31 108.7 0.0 4.3e-31 108.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY27861.1 - 0.0084 15.1 0.0 0.027 13.4 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY27861.1 - 0.027 13.8 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY27861.1 - 0.073 13.0 1.7 0.17 11.8 0.1 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.25 ORY27862.1 - 1e-69 234.9 0.0 1.2e-69 234.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY27862.1 - 7.5e-34 117.2 0.0 1e-33 116.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY27862.1 - 0.0021 17.1 0.3 0.004 16.2 0.3 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY27862.1 - 0.0025 17.2 0.2 0.0042 16.5 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY27862.1 - 0.01 15.8 0.1 0.092 12.6 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family CorA PF01544.18 ORY27863.1 - 4e-55 187.2 1.1 4e-55 187.2 1.1 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein RELT PF12606.8 ORY27863.1 - 2.9 6.9 6.9 14 4.7 1.8 2.6 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 An_peroxidase PF03098.15 ORY27982.1 - 7.2e-41 140.4 0.3 9e-41 140.0 0.3 1.0 1 0 0 1 1 1 1 Animal haem peroxidase CCSMST1 PF15013.6 ORY27983.1 - 1.1 9.4 0.0 1.1 9.4 0.0 2.4 3 0 0 3 3 3 0 CCSMST1 family DUF4281 PF14108.6 ORY27983.1 - 1.8 9.0 9.8 0.31 11.4 4.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4281) TMEM40 PF15817.5 ORY27983.1 - 3.3 7.5 7.3 13 5.5 0.3 3.2 1 1 1 3 3 3 0 Transmembrane protein 40 family CH PF00307.31 ORY27984.1 - 7.5e-18 64.7 0.0 1.8e-17 63.5 0.0 1.5 2 0 0 2 2 2 1 Calponin homology (CH) domain Melibiase_C PF17801.1 ORY27984.1 - 0.03 14.4 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 Alpha galactosidase C-terminal beta sandwich domain Amidohydro_3 PF07969.11 ORY27986.1 - 9.6e-15 55.0 1.3 5.7e-09 36.0 0.1 3.2 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 ORY27986.1 - 7.5e-14 51.8 0.9 4.8e-10 39.3 0.0 3.3 3 0 0 3 3 3 3 Amidohydrolase family DUF4510 PF14971.6 ORY27988.1 - 0.03 14.7 0.1 0.053 13.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) Hrs_helical PF12210.8 ORY27988.1 - 0.057 14.0 1.1 0.098 13.2 0.3 1.9 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Thioredoxin_4 PF13462.6 ORY28107.1 - 0.016 15.3 0.0 0.022 14.9 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin NAM-associated PF14303.6 ORY28110.1 - 9.7e-13 49.2 10.8 1.1e-11 45.7 10.8 2.0 1 1 0 1 1 1 1 No apical meristem-associated C-terminal domain Exonuc_VIII PF06630.11 ORY28110.1 - 0.0016 18.3 0.1 0.0036 17.2 0.1 1.5 1 1 0 1 1 1 1 Enterobacterial exodeoxyribonuclease VIII ESP PF16590.5 ORY28110.1 - 0.71 10.2 3.9 3.1 8.1 3.9 1.9 1 1 0 1 1 1 0 Exocrine gland-secreting peptide SeqA_N PF17206.3 ORY28111.1 - 0.073 12.4 0.2 0.71 9.2 0.0 2.1 2 0 0 2 2 2 0 SeqA protein N-terminal domain CHCH PF06747.13 ORY28112.1 - 3.5e-07 30.2 3.9 4.4e-07 29.9 3.9 1.1 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.9 ORY28112.1 - 0.008 16.3 0.7 0.0086 16.2 0.7 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CX9C PF16860.5 ORY28112.1 - 0.021 14.8 1.7 0.029 14.4 1.7 1.1 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, STAS PF01740.21 ORY28113.1 - 4.9e-05 23.0 0.0 8.4e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 STAS domain LRR_9 PF14580.6 ORY28114.1 - 6.8e-59 198.3 39.7 4.9e-19 68.5 2.4 8.2 3 2 4 7 7 7 7 Leucine-rich repeat LRR_4 PF12799.7 ORY28114.1 - 7.8e-54 178.7 89.4 1.5e-08 34.8 3.4 16.6 9 4 10 21 21 21 17 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY28114.1 - 1.6e-48 162.3 76.7 6.4e-13 48.3 4.7 12.1 7 3 5 13 13 13 11 Leucine rich repeat LRR_6 PF13516.6 ORY28114.1 - 0.00041 20.2 55.0 1.1 9.5 0.2 16.4 18 1 1 19 19 19 4 Leucine Rich repeat DUF3744 PF12558.8 ORY28114.1 - 0.12 13.2 0.5 10 6.9 0.0 4.2 3 0 0 3 3 3 0 ATP-binding cassette cobalt transporter LRR_5 PF13306.6 ORY28114.1 - 0.96 9.4 22.0 0.2 11.6 1.3 6.0 5 1 0 5 5 5 0 BspA type Leucine rich repeat region (6 copies) AF0941-like PF14591.6 ORY28114.1 - 2.2 8.9 5.5 3.5 8.2 3.3 2.5 2 0 0 2 2 2 0 AF0941-like DUF4679 PF15728.5 ORY28115.1 - 8.5 5.3 9.2 16 4.4 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) bZIP_1 PF00170.21 ORY28116.1 - 0.002 18.2 6.5 0.0046 17.0 6.5 1.7 1 0 0 1 1 1 1 bZIP transcription factor zf-C2HE PF16278.5 ORY28116.1 - 0.06 13.8 0.1 0.16 12.4 0.1 1.8 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger FliD_N PF02465.18 ORY28116.1 - 0.062 14.0 0.6 0.16 12.7 0.6 1.6 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Fis1_TPR_C PF14853.6 ORY28116.1 - 0.2 11.7 1.1 24 5.1 0.0 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat bZIP_1 PF00170.21 ORY28117.1 - 0.00036 20.6 6.7 0.00043 20.3 3.6 2.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORY28117.1 - 0.43 10.7 8.9 0.2 11.7 3.8 2.7 3 0 0 3 3 3 0 Basic region leucine zipper adh_short PF00106.25 ORY28118.1 - 1.2e-07 31.4 0.0 1.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY28118.1 - 0.011 15.2 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY28118.1 - 0.035 14.0 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 KR domain zinc_ribbon_6 PF14599.6 ORY28118.1 - 0.18 11.8 1.2 1.3 9.1 1.3 2.1 2 0 0 2 2 2 0 Zinc-ribbon adh_short_C2 PF13561.6 ORY28120.1 - 3.3e-06 26.8 0.0 3.8e-06 26.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY28120.1 - 0.017 14.6 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase Methyltransf_31 PF13847.6 ORY28121.1 - 8.3e-06 25.7 0.0 6.9e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORY28121.1 - 1e-05 25.0 0.0 0.0019 17.6 0.0 2.1 1 1 1 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 ORY28121.1 - 0.00032 21.3 0.0 0.0091 16.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY28121.1 - 0.00047 20.7 0.0 0.0049 17.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY28121.1 - 0.00092 19.1 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORY28121.1 - 0.045 13.5 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 ORY28121.1 - 0.1 13.3 0.0 0.19 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Nkap_C PF06047.11 ORY28236.1 - 7.2e-18 64.6 1.0 1.6e-17 63.5 1.0 1.5 1 1 0 1 1 1 1 NF-kappa-B-activating protein C-terminal domain Histone PF00125.24 ORY28239.1 - 3.5e-52 176.2 1.9 3.9e-52 176.1 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORY28239.1 - 5.2e-05 23.3 0.3 9e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 ORY28239.1 - 6.9e-05 23.2 0.0 0.0001 22.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 ORY28239.1 - 0.00019 22.0 1.2 0.00023 21.8 1.2 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 ORY28239.1 - 0.018 15.3 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY28239.1 - 0.13 12.3 0.1 0.23 11.6 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 ORY28240.1 - 2.5e-08 34.0 0.1 3e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 ORY28240.1 - 5.9e-05 23.1 0.1 8.6e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 ORY28240.1 - 0.0001 22.6 0.1 0.00014 22.2 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 ORY28240.1 - 0.0002 21.7 0.2 0.00023 21.6 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY28240.1 - 0.00034 20.8 0.1 0.00068 19.9 0.0 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY28240.1 - 0.02 14.9 0.0 0.023 14.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORY28240.1 - 0.058 13.4 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 ORY28240.1 - 0.17 12.4 0.0 0.34 11.5 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A UPF0137 PF03677.13 ORY28240.1 - 0.2 11.4 0.1 0.24 11.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Prefoldin PF02996.17 ORY28241.1 - 4.4e-19 68.6 2.4 4.4e-19 68.6 2.4 1.4 1 1 0 1 1 1 1 Prefoldin subunit IF-2B PF01008.17 ORY28242.1 - 3.1e-71 239.9 0.1 3.6e-71 239.7 0.1 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Peroxin-22 PF12827.7 ORY28242.1 - 0.094 12.6 0.1 0.38 10.7 0.0 2.0 2 1 1 3 3 3 0 Peroxisomal biogenesis protein family PWI PF01480.17 ORY28242.1 - 0.11 12.8 0.1 1.4 9.3 0.1 2.3 2 0 0 2 2 2 0 PWI domain p450 PF00067.22 ORY28243.1 - 2.8e-79 267.0 0.1 3.5e-79 266.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF359 PF04019.12 ORY28243.1 - 0.0089 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF359) Arm PF00514.23 ORY28244.1 - 8.2e-36 121.0 14.7 1.3e-06 28.2 0.0 10.3 10 0 0 10 10 10 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 ORY28244.1 - 2.7e-14 53.3 4.8 0.0002 21.6 0.1 5.3 1 1 3 6 6 6 5 HEAT repeats EDR1 PF14381.6 ORY28244.1 - 3e-11 43.4 0.0 7.4e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 Arm_2 PF04826.13 ORY28244.1 - 2.7e-10 40.2 4.9 0.011 15.2 1.4 4.2 2 2 1 3 3 3 3 Armadillo-like HEAT PF02985.22 ORY28244.1 - 1.5e-07 31.0 6.3 7.5 7.1 0.0 8.1 8 0 0 8 8 8 1 HEAT repeat Cnd1 PF12717.7 ORY28244.1 - 1.2e-06 28.7 7.3 0.013 15.5 0.2 4.1 2 2 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 ORY28244.1 - 9.1e-05 21.2 5.5 0.021 13.4 0.3 2.9 1 1 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.6 ORY28244.1 - 0.00012 22.5 4.3 4.2 8.0 0.0 4.9 4 1 0 4 4 4 2 HEAT-like repeat KAP PF05804.12 ORY28244.1 - 0.037 12.2 2.5 0.69 8.0 0.2 2.2 2 0 0 2 2 2 0 Kinesin-associated protein (KAP) WD40 PF00400.32 ORY28245.1 - 0.00062 20.5 8.6 0.19 12.6 0.3 4.7 5 1 0 5 5 5 2 WD domain, G-beta repeat Plavaka PF18759.1 ORY28249.1 - 5.3e-43 147.5 0.0 7.4e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase NifW PF03206.14 ORY28249.1 - 0.0073 16.8 0.1 0.02 15.4 0.1 1.7 1 0 0 1 1 1 1 Nitrogen fixation protein NifW NCE101 PF11654.8 ORY28249.1 - 0.029 14.1 0.0 0.092 12.5 0.0 1.8 1 0 0 1 1 1 0 Non-classical export protein 1 Siva PF05458.12 ORY28250.1 - 0.05 13.3 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Pet191_N PF10203.9 ORY28251.1 - 3.5 8.0 8.1 7.6 6.9 1.1 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Branch PF02485.21 ORY28364.1 - 3.2e-07 30.1 0.0 7e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Core-2/I-Branching enzyme ABC_membrane PF00664.23 ORY28365.1 - 9.7e-57 192.7 17.2 2e-34 119.5 4.7 3.3 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY28365.1 - 3.4e-37 128.0 0.0 4.3e-17 62.9 0.0 3.4 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY28365.1 - 2e-08 34.0 0.0 0.0012 18.4 0.0 3.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 ORY28365.1 - 0.011 15.3 0.1 0.022 14.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 ORY28365.1 - 0.042 12.9 0.0 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 ORY28365.1 - 0.13 12.0 0.3 0.34 10.7 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Lipoxygenase PF00305.19 ORY28366.1 - 3.9e-69 233.8 0.2 2.6e-67 227.8 0.1 2.2 1 1 1 2 2 2 2 Lipoxygenase PLAT PF01477.23 ORY28366.1 - 0.0019 18.7 0.4 0.0071 16.9 0.4 2.0 1 1 0 1 1 1 1 PLAT/LH2 domain Ank_2 PF12796.7 ORY28367.1 - 1.2e-06 29.0 0.0 0.016 15.8 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY28367.1 - 9.6e-05 22.9 0.0 0.03 14.9 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Nucleoporin_FG PF13634.6 ORY28368.1 - 6.1e-42 142.4 171.9 1.3e-15 58.0 20.9 6.9 1 1 6 7 7 7 7 Nucleoporin FG repeat region Nsp1_C PF05064.13 ORY28368.1 - 5.6e-28 97.1 0.1 1.1e-27 96.2 0.1 1.3 1 0 0 1 1 1 1 Nsp1-like C-terminal region Lipoprotein_6 PF01441.19 ORY28368.1 - 0.039 14.0 0.1 0.064 13.3 0.1 1.2 1 0 0 1 1 1 0 Lipoprotein Baculo_PEP_C PF04513.12 ORY28368.1 - 0.22 11.6 1.8 9 6.3 0.0 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HET PF06985.11 ORY28370.1 - 2.7e-07 31.0 0.4 2.2e-06 28.1 0.0 2.2 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) IL17R_fnIII_D1 PF16556.5 ORY28370.1 - 0.028 14.1 0.5 6.8 6.3 0.1 2.3 2 0 0 2 2 2 0 Interleukin-17 receptor, fibronectin-III-like domain 1 DUF1356 PF07092.12 ORY28371.1 - 0.007 15.7 2.4 0.013 14.7 2.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) DUF4347 PF14252.6 ORY28372.1 - 0.12 12.2 0.1 0.18 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) PDEase_II PF02112.15 ORY28373.1 - 9.1e-57 192.7 0.0 2.5e-33 115.6 0.0 2.1 1 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.7 ORY28373.1 - 0.0078 15.7 0.0 0.011 15.3 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain WW PF00397.26 ORY28375.1 - 0.086 12.9 2.4 0.21 11.7 2.4 1.7 1 0 0 1 1 1 0 WW domain Tweety PF04906.13 ORY28375.1 - 0.21 10.2 3.5 0.2 10.3 2.3 1.5 2 0 0 2 2 2 0 Tweety adh_short PF00106.25 ORY28376.1 - 6.9e-77 257.3 12.6 3.1e-41 141.0 2.9 2.5 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY28376.1 - 8.5e-64 215.3 12.3 9.7e-34 116.9 4.4 2.8 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY28376.1 - 5.2e-32 111.2 10.6 5e-16 59.1 0.9 2.7 3 0 0 3 3 3 2 KR domain MaoC_dehydratas PF01575.19 ORY28376.1 - 4.4e-27 94.1 0.0 1.2e-26 92.7 0.0 1.8 1 0 0 1 1 1 1 MaoC like domain THF_DHG_CYH_C PF02882.19 ORY28376.1 - 3.7e-06 26.4 4.2 0.00098 18.5 0.3 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MaoC_dehydrat_N PF13452.6 ORY28376.1 - 6.5e-05 23.1 0.0 0.0047 17.1 0.0 2.6 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Casein_kappa PF00997.18 ORY28376.1 - 0.019 15.0 0.3 2.8 8.0 0.2 2.4 1 1 0 2 2 2 0 Kappa casein 3HCDH_N PF02737.18 ORY28376.1 - 0.15 12.0 10.0 0.27 11.1 1.7 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PglL_A PF15864.5 ORY28376.1 - 1.4 8.7 7.9 5.6 6.8 1.0 2.5 2 0 0 2 2 2 0 Protein glycosylation ligase Skp1 PF01466.19 ORY28377.1 - 2.1e-27 95.0 1.2 3.5e-27 94.2 1.2 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 ORY28377.1 - 3.8e-26 91.0 1.3 4.9e-26 90.7 0.1 1.9 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.31 ORY28377.1 - 0.0014 18.9 0.0 0.023 14.9 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain DUF2431 PF10354.9 ORY28378.1 - 2.2e-53 181.0 0.0 3.5e-53 180.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) MTS PF05175.14 ORY28378.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain AA_permease_2 PF13520.6 ORY28380.1 - 7.5e-54 183.2 58.7 9e-54 182.9 58.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY28380.1 - 1.9e-15 56.5 52.6 2.4e-15 56.1 52.6 1.0 1 0 0 1 1 1 1 Amino acid permease AAA_33 PF13671.6 ORY28381.1 - 7.6e-06 26.1 0.0 1.1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 ORY28381.1 - 0.00034 20.8 0.0 0.00049 20.3 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase Cytidylate_kin PF02224.18 ORY28381.1 - 0.00047 20.0 0.0 0.00056 19.7 0.0 1.1 1 0 0 1 1 1 1 Cytidylate kinase ABC_tran PF00005.27 ORY28381.1 - 0.0019 18.7 0.0 0.0028 18.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 ORY28381.1 - 0.0065 17.0 0.0 0.0097 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 ORY28381.1 - 0.02 15.3 0.0 0.14 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 ORY28381.1 - 0.031 14.2 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_22 PF13401.6 ORY28381.1 - 0.031 14.6 0.0 0.05 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 ORY28381.1 - 0.13 12.0 0.1 0.17 11.6 0.1 1.1 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.6 ORY28381.1 - 0.13 12.0 0.1 0.28 10.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cytidylate_kin2 PF13189.6 ORY28381.1 - 0.17 12.0 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family Zeta_toxin PF06414.12 ORY28381.1 - 0.2 10.9 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin DNA_pol_B PF00136.21 ORY28383.1 - 4.8e-120 401.4 0.0 7.8e-120 400.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 ORY28383.1 - 2.6e-45 154.5 0.4 4e-45 153.8 0.4 1.3 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 ORY28383.1 - 1.9e-38 132.4 0.0 5.7e-38 130.9 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B_2 PF03175.13 ORY28383.1 - 9.5e-05 21.4 0.0 0.00022 20.2 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase type B, organellar and viral PTP_tm PF18861.1 ORY28384.1 - 0.034 14.1 0.3 0.044 13.8 0.3 1.2 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J Amnionless PF14828.6 ORY28384.1 - 0.065 12.0 0.1 0.079 11.8 0.1 1.0 1 0 0 1 1 1 0 Amnionless TPPK_C PF12555.8 ORY28385.1 - 0.29 11.2 2.8 0.64 10.1 2.8 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal Sel1 PF08238.12 ORY28386.1 - 0.11 13.2 1.6 0.82 10.4 0.0 2.7 3 0 0 3 3 3 0 Sel1 repeat Ank_4 PF13637.6 ORY28388.1 - 6.4e-18 64.9 0.2 8.2e-13 48.6 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY28388.1 - 1.3e-16 60.9 0.1 6.5e-16 58.7 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY28388.1 - 1.2e-15 57.2 0.0 7.3e-07 29.4 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 ORY28388.1 - 1.5e-14 52.7 0.3 3.2e-07 30.1 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 ORY28388.1 - 4.4e-11 42.8 0.4 5.5e-09 36.1 0.0 2.5 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY28389.1 - 4e-28 97.8 2.3 5.4e-15 55.8 0.4 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY28389.1 - 3.2e-22 78.6 2.8 2.2e-08 34.4 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY28389.1 - 1.6e-20 72.6 0.6 1.4e-05 25.3 0.0 4.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 ORY28389.1 - 4.2e-15 54.3 0.1 0.0034 17.8 0.0 3.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 ORY28389.1 - 6e-15 55.1 0.2 1.5e-08 34.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF3298 PF11738.8 ORY28391.1 - 0.025 15.6 0.0 0.042 14.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3298) FA_FANCE PF11510.8 ORY28391.1 - 0.092 12.1 0.6 0.11 11.8 0.6 1.2 1 0 0 1 1 1 0 Fanconi Anaemia group E protein FANCE Methyltransf_23 PF13489.6 ORY28393.1 - 2.4e-20 73.0 0.0 3.1e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY28393.1 - 3.5e-11 43.7 0.0 9.3e-11 42.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY28393.1 - 1.4e-06 28.2 0.0 4.8e-06 26.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY28393.1 - 4.9e-06 27.2 0.0 2.1e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY28393.1 - 2.8e-05 24.7 0.0 0.00012 22.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY28393.1 - 0.00048 19.5 0.0 0.17 11.2 0.0 2.1 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family SP_C-Propep PF08999.10 ORY28394.1 - 0.065 13.0 0.6 0.084 12.7 0.6 1.2 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide PALP PF00291.25 ORY28395.1 - 1.2e-62 212.0 0.3 1.3e-62 211.9 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PALP PF00291.25 ORY28396.1 - 1.8e-67 227.9 0.5 2.3e-67 227.5 0.5 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FAD_oxidored PF12831.7 ORY28396.1 - 0.058 12.7 0.2 0.086 12.2 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase PALP PF00291.25 ORY28397.1 - 7.9e-58 196.2 2.7 8e-56 189.6 2.7 2.0 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Pro_isomerase PF00160.21 ORY28398.1 - 1e-94 315.0 10.8 1.6e-47 161.7 0.3 2.3 3 0 0 3 3 3 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PALP PF00291.25 ORY28399.1 - 4.1e-64 216.8 0.0 4.8e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Succ_CoA_lig PF13607.6 ORY28399.1 - 0.097 12.5 0.1 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain DUF1688 PF07958.11 ORY28400.1 - 3.8e-111 371.8 0.0 3.5e-108 362.0 0.0 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1688) DUF726 PF05277.12 ORY28402.1 - 0.00022 20.3 0.0 0.00036 19.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF1749 PF08538.10 ORY28402.1 - 0.12 11.4 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF1201 PF06716.11 ORY28403.1 - 0.19 11.8 4.1 0.51 10.4 3.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1201) Hydrolase_4 PF12146.8 ORY28404.1 - 5e-17 62.0 0.1 2.9e-13 49.6 0.0 2.7 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY28404.1 - 5.6e-12 45.8 0.0 6.8e-10 39.0 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 ORY28404.1 - 4e-06 26.9 0.0 0.00022 21.2 0.0 2.6 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 ORY28404.1 - 1.6e-05 25.6 0.0 2.4e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 ORY28404.1 - 3.3e-05 23.6 0.0 0.00014 21.5 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 ORY28404.1 - 9.4e-05 22.3 0.0 0.017 14.9 0.0 3.1 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.20 ORY28404.1 - 0.0014 18.3 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S15 PF02129.18 ORY28404.1 - 0.0018 17.9 0.0 0.01 15.5 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PGAP1 PF07819.13 ORY28404.1 - 0.0072 16.1 0.0 0.12 12.1 0.0 2.1 1 1 0 1 1 1 1 PGAP1-like protein Peptidase_S9 PF00326.21 ORY28404.1 - 0.0095 15.4 0.0 0.046 13.2 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 ORY28404.1 - 0.13 11.9 0.1 0.29 10.8 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase (FSH1) AXE1 PF05448.12 ORY28404.1 - 0.2 10.3 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) NBD_C PF17042.5 ORY28405.1 - 0.24 11.9 2.0 0.48 10.9 2.0 1.5 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain DUF1179 PF06678.11 ORY28405.1 - 1.2 9.2 5.1 1.9 8.5 4.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) Glyco_trans_1_4 PF13692.6 ORY28406.1 - 3.3e-05 24.3 0.0 5.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 ORY28406.1 - 5.4e-05 22.8 0.0 9.4e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 zf-C2H2_10 PF16588.5 ORY28408.1 - 0.28 11.0 2.2 0.5 10.1 2.2 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger PALP PF00291.25 ORY28409.1 - 5.8e-66 222.9 0.1 6.6e-66 222.7 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 ORY28409.1 - 0.036 14.0 0.2 0.3 11.1 0.1 2.5 2 1 0 2 2 2 0 Zinc-binding dehydrogenase PGF-CTERM PF18204.1 ORY28410.1 - 2.1 8.4 5.1 5.8 7.0 5.1 1.8 1 0 0 1 1 1 0 PGF-CTERM motif PI31_Prot_N PF11566.8 ORY28411.1 - 1.7e-19 70.2 0.0 2.9e-19 69.5 0.0 1.3 1 1 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 ORY28411.1 - 3.1e-09 37.9 14.9 3.1e-09 37.9 14.9 3.4 2 1 1 3 3 3 1 PI31 proteasome regulator DENN PF02141.21 ORY28412.1 - 7.9e-52 175.9 0.0 1.8e-51 174.7 0.0 1.7 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 ORY28412.1 - 4.8e-17 62.5 1.7 1.6e-16 60.8 1.7 2.0 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 ORY28412.1 - 2.6e-08 33.7 0.6 6.9e-08 32.4 0.6 1.8 1 0 0 1 1 1 1 dDENN domain SPA PF08616.10 ORY28412.1 - 0.00057 19.8 0.1 0.0013 18.7 0.1 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis C1_1 PF00130.22 ORY28412.1 - 0.0014 18.5 0.1 0.0031 17.3 0.1 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3552 PF12072.8 ORY28412.1 - 0.004 16.6 0.4 0.0076 15.7 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) Regulator_TrmB PF11495.8 ORY28412.1 - 0.021 14.0 0.1 0.045 12.9 0.1 1.5 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB PHD PF00628.29 ORY28412.1 - 0.052 13.4 0.7 0.14 12.1 0.7 1.7 1 0 0 1 1 1 0 PHD-finger Ribosomal_S24e PF01282.19 ORY28413.1 - 1.7e-34 117.6 0.9 1.8e-34 117.5 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein S24e adh_short PF00106.25 ORY28414.1 - 3.6e-30 104.9 0.0 5.6e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY28414.1 - 6.1e-19 68.5 0.0 1.2e-18 67.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY28414.1 - 0.002 18.1 0.1 0.0051 16.8 0.1 1.8 1 1 0 1 1 1 1 KR domain Homeodomain PF00046.29 ORY28415.1 - 8.2e-11 41.6 0.5 1.5e-10 40.7 0.5 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY28415.1 - 0.003 17.4 0.0 0.044 13.7 0.0 2.5 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 ORY28416.1 - 3.3e-13 49.3 0.7 5.5e-13 48.6 0.7 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY28416.1 - 0.0064 16.4 0.3 0.045 13.6 0.1 2.3 2 0 0 2 2 2 1 Homeobox KN domain Terminase_5 PF06056.12 ORY28416.1 - 0.12 12.2 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Homeodomain PF00046.29 ORY28417.1 - 2.3e-11 43.4 0.3 3.6e-11 42.7 0.3 1.3 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 ORY28417.1 - 0.005 16.6 0.1 0.0088 15.8 0.1 1.3 1 0 0 1 1 1 1 Homeodomain-like domain Homeobox_KN PF05920.11 ORY28417.1 - 0.012 15.5 0.1 0.03 14.2 0.1 1.8 1 0 0 1 1 1 0 Homeobox KN domain DUF2285 PF10074.9 ORY28417.1 - 0.041 14.5 0.1 0.068 13.8 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2285) IF2_N PF04760.15 ORY28417.1 - 0.089 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region MarR_2 PF12802.7 ORY28417.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 MarR family MerR_1 PF13411.6 ORY28417.1 - 0.17 12.0 0.1 0.45 10.6 0.0 1.7 2 0 0 2 2 2 0 MerR HTH family regulatory protein adh_short PF00106.25 ORY28418.1 - 1e-26 93.6 0.0 1.7e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY28418.1 - 1.1e-17 64.4 0.0 1.8e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY28418.1 - 9.5e-11 41.9 0.0 1.4e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY28418.1 - 7e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 ORY28418.1 - 0.00098 18.5 0.5 0.021 14.2 0.2 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 ORY28418.1 - 0.054 12.6 0.1 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain DUF3889 PF13028.6 ORY28418.1 - 0.061 13.3 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) Ribosomal_S6e PF01092.19 ORY28418.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S6e DUF1647 PF07801.11 ORY28418.1 - 0.2 11.4 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) adh_short PF00106.25 ORY28419.1 - 2.3e-06 27.2 0.0 0.0026 17.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY28419.1 - 0.0048 16.5 0.0 0.0099 15.5 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY28420.1 - 2.1e-24 86.0 0.5 5.2e-18 65.2 0.7 3.1 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY28420.1 - 7.4e-13 48.6 0.2 3.7e-10 39.8 0.1 3.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY28420.1 - 5.5e-05 23.1 1.4 0.0071 16.3 0.8 2.4 1 1 1 2 2 2 2 KR domain Epimerase PF01370.21 ORY28420.1 - 0.0036 16.8 0.1 0.016 14.7 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORY28420.1 - 0.091 11.8 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_7 PF13241.6 ORY28420.1 - 0.17 12.3 0.0 0.36 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF2373 PF10180.9 ORY28421.1 - 0.05 13.4 0.1 0.095 12.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Lactamase_B_2 PF12706.7 ORY28422.1 - 2e-10 40.5 0.0 6e-05 22.7 0.0 2.9 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY28422.1 - 2.1e-10 40.9 0.2 1e-09 38.7 0.1 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 ORY28422.1 - 0.0024 17.5 0.0 0.37 10.5 0.0 2.4 2 0 0 2 2 2 2 tRNase Z endonuclease Thiamine_BP PF01910.17 ORY28423.1 - 6.6e-14 51.6 0.0 7.7e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Thiamine-binding protein Col_cuticle_N PF01484.17 ORY28424.1 - 0.02 15.0 0.2 0.029 14.4 0.2 1.3 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Glyco_tran_28_C PF04101.16 ORY28426.1 - 2e-24 86.5 0.0 3e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ASCH PF04266.14 ORY28426.1 - 0.0012 19.4 0.0 0.002 18.7 0.0 1.3 1 0 0 1 1 1 1 ASCH domain Thiamine_BP PF01910.17 ORY28428.1 - 4.5e-10 39.3 0.1 5.3e-10 39.1 0.1 1.1 1 0 0 1 1 1 1 Thiamine-binding protein Thiamine_BP PF01910.17 ORY28429.1 - 7.5e-06 25.8 0.0 2.2e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 Thiamine-binding protein Peptidase_S9 PF00326.21 ORY28431.1 - 2.9e-43 147.8 0.0 4.4e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ORY28431.1 - 5.2e-06 25.9 0.0 0.00088 18.6 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 ORY28431.1 - 3.1e-05 23.6 0.1 7.4e-05 22.4 0.1 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 ORY28431.1 - 5.9e-05 22.8 0.5 0.092 12.4 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 ORY28431.1 - 9.9e-05 22.1 0.0 0.12 12.0 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 ORY28431.1 - 0.00019 20.2 0.0 0.00071 18.4 0.0 1.8 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) PD40 PF07676.12 ORY28431.1 - 0.0011 18.8 0.9 2.1 8.4 0.1 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat BAAT_C PF08840.11 ORY28431.1 - 0.03 14.3 0.0 0.21 11.5 0.0 2.0 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 ORY28431.1 - 0.03 14.2 0.1 0.36 10.7 0.1 2.3 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 ORY28431.1 - 0.045 13.9 0.0 0.092 12.9 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Esterase PF00756.20 ORY28431.1 - 0.061 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative esterase PQQ_3 PF13570.6 ORY28431.1 - 0.09 13.3 1.4 9.6 6.8 0.0 3.2 2 0 0 2 2 2 0 PQQ-like domain DUF829 PF05705.14 ORY28431.1 - 0.12 12.3 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Esterase_phd PF10503.9 ORY28431.1 - 0.12 11.8 0.6 3.8 6.9 0.2 2.6 2 1 0 2 2 2 0 Esterase PHB depolymerase FSH1 PF03959.13 ORY28431.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Mannosyl_trans3 PF11051.8 ORY28434.1 - 1.2e-42 146.2 0.0 2e-42 145.5 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 ORY28434.1 - 0.027 14.5 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase DUF4797 PF16051.5 ORY28435.1 - 0.027 14.4 0.3 0.056 13.4 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4797) FAP PF07174.11 ORY28435.1 - 1.1 8.7 13.0 0.71 9.3 10.5 1.7 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) MGC-24 PF05283.11 ORY28435.1 - 3.9 7.9 6.8 3.1 8.2 5.6 1.5 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF4436 PF14494.6 ORY28439.1 - 2.2e-19 69.8 2.9 2.2e-19 69.8 2.9 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4436) COesterase PF00135.28 ORY28439.1 - 0.15 10.9 0.1 0.2 10.5 0.1 1.1 1 0 0 1 1 1 0 Carboxylesterase family tRNA-synt_2b PF00587.25 ORY28441.1 - 3.2e-34 118.4 0.0 6.4e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 ORY28441.1 - 1.4e-20 73.5 8.4 3.9e-20 72.1 8.4 1.7 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain LUC7 PF03194.15 ORY28441.1 - 0.052 13.2 2.3 0.086 12.5 2.3 1.4 1 0 0 1 1 1 0 LUC7 N_terminus Glutaredoxin2_C PF04399.13 ORY28441.1 - 0.062 13.1 0.4 0.56 10.1 0.0 2.6 2 1 0 2 2 2 0 Glutaredoxin 2, C terminal domain Pkinase PF00069.25 ORY28442.1 - 2.2e-26 92.8 0.0 2.7e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY28442.1 - 5.2e-13 48.9 0.0 6.5e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase AbiGi PF10899.8 ORY28442.1 - 0.14 12.0 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative abortive phage resistance protein AbiGi, antitoxin Pkinase PF00069.25 ORY28443.1 - 2.9e-14 53.1 0.0 4e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY28443.1 - 8.5e-07 28.5 0.0 1.2e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UQ_con PF00179.26 ORY28444.1 - 1.1e-34 119.1 0.0 1.2e-34 118.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme GPI-anchored PF10342.9 ORY28445.1 - 1.1e-08 35.8 0.0 1.7e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family E1_DerP2_DerF2 PF02221.15 ORY28445.1 - 0.0046 17.4 0.0 0.011 16.2 0.0 1.6 2 0 0 2 2 2 1 ML domain PKD PF00801.20 ORY28445.1 - 0.017 14.9 0.0 0.13 12.1 0.0 2.2 1 1 1 2 2 2 0 PKD domain DUF3313 PF11769.8 ORY28445.1 - 0.16 11.7 0.6 0.19 11.5 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3313) Big_7 PF17957.1 ORY28445.1 - 0.41 11.4 8.0 17 6.3 6.0 3.4 1 1 1 2 2 2 0 Bacterial Ig domain NPCBM_assoc PF10633.9 ORY28445.1 - 0.8 10.0 9.2 2.3 8.6 0.3 3.0 2 1 1 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase peroxidase PF00141.23 ORY28446.1 - 7.5e-42 143.6 0.0 1.2e-41 143.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase SPATA1_C PF15743.5 ORY28447.1 - 0.0045 17.1 3.4 0.0071 16.4 3.4 1.2 1 0 0 1 1 1 1 Spermatogenesis-associated C-terminus DUF3015 PF11220.8 ORY28447.1 - 0.014 15.3 1.2 0.032 14.1 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) FlaC_arch PF05377.11 ORY28447.1 - 0.18 12.2 2.9 0.8 10.1 0.1 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4355 PF14265.6 ORY28447.1 - 0.4 10.9 6.8 0.74 10.1 6.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) TMPIT PF07851.13 ORY28447.1 - 4 6.6 5.7 6.3 6.0 5.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein Fzo_mitofusin PF04799.13 ORY28573.1 - 0.81 9.2 4.4 3.4 7.2 0.4 3.0 3 0 0 3 3 3 0 fzo-like conserved region zf-HC5HC2H PF13771.6 ORY28574.1 - 0.082 13.2 1.8 0.3 11.4 1.8 1.9 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 ORY28575.1 - 0.041 13.4 7.8 0.041 13.4 7.8 1.8 2 0 0 2 2 2 0 PHD-finger PHD PF00628.29 ORY28575.1 - 0.28 11.1 10.1 0.58 10.1 10.1 1.6 1 1 0 1 1 1 0 PHD-finger PIF1 PF05970.14 ORY28578.1 - 4.9e-06 25.9 0.2 6.6e-06 25.5 0.2 1.2 1 0 0 1 1 1 1 PIF1-like helicase DUF4926 PF16277.5 ORY28578.1 - 6.5e-05 22.2 0.0 9.2e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4926) SH3_13 PF18335.1 ORY28578.1 - 0.00017 21.4 0.1 0.0004 20.2 0.0 1.6 2 0 0 2 2 2 1 ATP-dependent RecD-like DNA helicase SH3 domain SBDS_C PF09377.10 ORY28578.1 - 0.0034 17.4 0.2 0.033 14.2 0.2 1.9 1 1 1 2 2 2 1 SBDS protein C-terminal domain TFIIF_alpha PF05793.12 ORY28699.1 - 0.00041 19.1 11.5 0.00043 19.0 11.5 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 ORY28699.1 - 0.0013 17.1 10.2 0.0013 17.1 10.2 1.1 1 0 0 1 1 1 1 CDC45-like protein SEEEED PF14797.6 ORY28699.1 - 0.056 13.6 28.3 0.088 13.0 28.3 1.2 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex NifQ PF04891.12 ORY28699.1 - 0.88 9.9 7.8 4.3 7.7 1.1 2.2 1 1 1 2 2 2 0 NifQ SIR4_SID PF16991.5 ORY28699.1 - 1.1 9.3 12.2 1.8 8.6 12.2 1.4 1 0 0 1 1 1 0 Sir4 SID domain RR_TM4-6 PF06459.12 ORY28699.1 - 2.9 7.6 8.8 4.2 7.1 8.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Lyase_8_N PF08124.11 ORY28699.1 - 3 6.7 6.5 1.4 7.8 2.6 1.9 1 1 1 2 2 2 0 Polysaccharide lyase family 8, N terminal alpha-helical domain CobT PF06213.12 ORY28699.1 - 3.1 7.1 16.4 4.2 6.7 16.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.10 ORY28699.1 - 4.3 6.6 21.2 6.5 6.0 21.2 1.3 1 0 0 1 1 1 0 BUD22 CPSF100_C PF13299.6 ORY28699.1 - 5.4 7.2 9.1 11 6.2 9.1 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 ORY28699.1 - 7.7 5.2 7.5 7.9 5.1 7.5 1.2 1 0 0 1 1 1 0 Presenilin SOBP PF15279.6 ORY28699.1 - 8.1 7.0 9.3 10 6.6 9.3 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein SRP40_C PF05022.12 ORY28701.1 - 2.6e-29 101.9 6.0 2.9e-29 101.7 6.0 1.0 1 0 0 1 1 1 1 SRP40, C-terminal domain Peptidase_S49_N PF08496.10 ORY28701.1 - 0.096 12.7 0.3 0.5 10.4 0.0 1.9 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Myb_Cef PF11831.8 ORY28702.1 - 3.3e-31 108.7 3.6 3.3e-31 108.7 3.6 4.6 5 0 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-bind_6 PF13921.6 ORY28702.1 - 5.7e-11 42.5 3.6 1.3e-10 41.3 3.6 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY28702.1 - 2e-10 40.7 5.4 1e-09 38.4 0.6 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Glyco_transf_28 PF03033.20 ORY28703.1 - 1.5e-12 47.7 0.0 2.9e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 ORY28703.1 - 1.4e-05 25.2 0.0 2.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 ORY28703.1 - 0.02 13.7 0.0 0.08 11.7 0.0 1.8 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 ORY28704.1 - 1.1e-07 32.0 0.0 1.3e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 ORY28704.1 - 0.0022 16.9 0.0 0.0027 16.6 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase RRM_1 PF00076.22 ORY28705.1 - 4.1e-33 113.0 0.0 4.1e-16 58.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 ORY28705.1 - 0.00066 19.7 0.1 0.13 12.4 0.1 2.2 2 0 0 2 2 2 2 Limkain b1 OB_RNB PF08206.11 ORY28705.1 - 0.0023 17.6 1.0 1.7 8.4 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain RRM_5 PF13893.6 ORY28705.1 - 0.041 13.5 0.0 7.3 6.2 0.0 2.2 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CBS PF00571.28 ORY28706.1 - 5.9e-31 106.7 0.4 4.6e-07 30.2 0.0 5.0 5 0 0 5 5 5 4 CBS domain MscL PF01741.18 ORY28707.1 - 0.61 10.4 5.0 3.4 8.0 4.3 2.5 1 1 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL RRM_1 PF00076.22 ORY28708.1 - 1.1e-06 28.3 0.0 3.2e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sigma70_r1_1 PF03979.14 ORY28708.1 - 0.043 13.9 0.1 0.17 12.0 0.1 1.9 1 1 1 2 2 2 0 Sigma-70 factor, region 1.1 Esterase_phd PF10503.9 ORY28708.1 - 0.14 11.6 0.0 0.8 9.1 0.0 2.1 2 0 0 2 2 2 0 Esterase PHB depolymerase zf-Di19 PF05605.12 ORY28709.1 - 0.066 13.5 2.1 4.4 7.7 0.4 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Sporozoite_P67 PF05642.11 ORY28709.1 - 5.5 4.9 13.2 0.14 10.2 6.2 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen SWIB PF02201.18 ORY28711.1 - 4.4e-47 157.9 3.1 7.9e-27 92.9 0.0 3.9 4 1 0 4 4 4 2 SWIB/MDM2 domain DEK_C PF08766.11 ORY28711.1 - 2.9e-06 27.1 0.2 7.3e-06 25.8 0.2 1.7 1 0 0 1 1 1 1 DEK C terminal domain SDA1 PF05285.12 ORY28711.1 - 0.00095 18.7 15.9 0.00095 18.7 15.9 2.2 2 0 0 2 2 2 2 SDA1 CDC45 PF02724.14 ORY28711.1 - 0.0087 14.4 29.6 0.0054 15.1 13.0 2.1 2 0 0 2 2 2 2 CDC45-like protein TetR_C_11 PF16859.5 ORY28711.1 - 2.1 8.7 9.2 5.9 7.2 5.0 2.4 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Nop14 PF04147.12 ORY28711.1 - 3.1 5.9 38.1 0.07 11.3 19.0 2.1 2 0 0 2 2 2 0 Nop14-like family DUF4455 PF14643.6 ORY28712.1 - 0.17 10.5 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) DUF913 PF06025.12 ORY28712.1 - 3.2 6.6 6.7 5.1 6.0 0.2 2.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) SIKE PF05769.11 ORY28712.1 - 3.3 7.6 4.6 0.49 10.3 0.5 1.6 2 0 0 2 2 2 0 SIKE family SH3_9 PF14604.6 ORY28714.1 - 6.5e-22 77.1 0.0 6.6e-09 35.5 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 ORY28714.1 - 1.3e-16 59.9 0.0 1.4e-05 24.6 0.0 3.3 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 ORY28714.1 - 1.3e-08 34.4 0.0 0.053 13.2 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain Stevor PF17410.2 ORY28714.1 - 0.61 9.6 4.7 1.2 8.6 4.7 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame 2Fe-2S_thioredx PF01257.19 ORY28715.1 - 0.027 14.3 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin UDPGP PF01704.18 ORY28716.1 - 1.9e-57 194.8 0.0 2.4e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 ORY28716.1 - 0.029 14.7 0.0 0.063 13.6 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain TolB_N PF04052.13 ORY28716.1 - 0.096 12.9 0.0 0.45 10.7 0.0 2.0 2 0 0 2 2 2 0 TolB amino-terminal domain UDPGP PF01704.18 ORY28717.1 - 5.5e-54 183.4 0.0 7.1e-54 183.0 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 ORY28717.1 - 0.011 16.1 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain MINDY_DUB PF04424.13 ORY28718.1 - 0.047 13.7 0.0 0.076 13.0 0.0 1.5 1 1 0 1 1 1 0 MINDY deubiquitinase zf-Di19 PF05605.12 ORY28719.1 - 0.12 12.6 2.9 4.4 7.7 0.4 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding YrzO PF14142.6 ORY28720.1 - 0.73 9.8 3.5 1.7 8.6 3.5 1.6 1 0 0 1 1 1 0 YrzO-like protein DUF4200 PF13863.6 ORY28721.1 - 0.062 13.7 0.8 18 5.7 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) Cu-oxidase PF00394.22 ORY28722.1 - 7.8e-43 146.3 5.1 1.8e-41 141.9 0.2 3.4 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORY28722.1 - 8.8e-43 145.1 12.4 5.5e-41 139.3 1.7 3.8 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY28722.1 - 3.5e-36 123.9 6.0 2.4e-27 95.4 0.2 4.0 3 1 0 3 3 3 2 Multicopper oxidase PLAC8 PF04749.17 ORY28723.1 - 2.9e-07 31.4 7.0 6e-07 30.4 7.0 1.4 1 0 0 1 1 1 1 PLAC8 family NFRKB_winged PF14465.6 ORY28723.1 - 0.033 14.4 0.3 0.069 13.3 0.3 1.6 1 0 0 1 1 1 0 NFRKB Winged Helix-like ZapB PF06005.12 ORY28724.1 - 0.077 13.4 7.9 0.14 12.6 3.9 2.2 1 1 2 3 3 3 0 Cell division protein ZapB Methyltransf_31 PF13847.6 ORY28724.1 - 0.086 12.6 0.2 0.13 12.1 0.2 1.3 1 0 0 1 1 1 0 Methyltransferase domain Csm1_N PF18504.1 ORY28724.1 - 0.15 12.4 9.2 0.13 12.6 3.4 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain Seryl_tRNA_N PF02403.22 ORY28724.1 - 0.65 10.3 9.1 7.3 6.9 9.2 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.8 ORY28724.1 - 1.1 9.3 10.6 6.1 6.9 10.9 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding HALZ PF02183.18 ORY28724.1 - 1.2 9.4 7.9 0.31 11.3 1.2 2.8 3 1 0 3 3 3 0 Homeobox associated leucine zipper DUF16 PF01519.16 ORY28724.1 - 1.4 9.4 6.9 5.1 7.6 6.9 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 DivIC PF04977.15 ORY28724.1 - 5.7 6.8 10.4 2.1e+02 1.8 10.4 2.5 1 1 0 1 1 1 0 Septum formation initiator zf-C2H2_3rep PF18868.1 ORY28725.1 - 0.006 17.3 3.5 0.24 12.1 0.1 3.7 3 0 0 3 3 3 1 Zinc finger C2H2-type, 3 repeats Putative_PNPOx PF01243.20 ORY28725.1 - 0.066 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase zf-C2H2 PF00096.26 ORY28725.1 - 0.24 11.9 0.1 0.24 11.9 0.1 5.8 6 0 0 6 6 6 0 Zinc finger, C2H2 type Serglycin PF04360.12 ORY28725.1 - 0.28 11.1 1.8 0.56 10.2 1.8 1.4 1 0 0 1 1 1 0 Serglycin Anti-TRAP PF15777.5 ORY28725.1 - 0.81 9.7 3.6 19 5.3 0.0 3.6 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein OrsD PF12013.8 ORY28725.1 - 0.97 9.9 0.0 0.97 9.9 0.0 3.6 4 1 0 4 4 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zinc_ribbon_4 PF13717.6 ORY28725.1 - 1.6 8.7 8.0 64 3.6 0.0 4.2 4 0 0 4 4 4 0 zinc-ribbon domain zf-C2H2_4 PF13894.6 ORY28725.1 - 2.5 9.2 29.5 6.9 7.8 0.1 6.6 6 0 0 6 6 6 0 C2H2-type zinc finger zf-RING_7 PF02591.15 ORY28725.1 - 6.8 7.0 8.2 2 8.7 0.2 3.1 3 0 0 3 3 3 0 C4-type zinc ribbon domain DUF2387 PF09526.10 ORY28725.1 - 7.4 6.8 10.2 3.9 7.7 0.1 4.2 4 0 0 4 4 4 0 Probable metal-binding protein (DUF2387) IBR PF01485.21 ORY28725.1 - 7.6 6.8 11.8 9.4 6.6 0.4 3.7 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain BUD22 PF09073.10 ORY28727.1 - 0.00011 21.7 33.6 0.00034 20.1 27.6 2.5 2 0 0 2 2 2 2 BUD22 zf-RRN7 PF11781.8 ORY28727.1 - 0.016 14.9 0.0 26 4.6 0.0 3.6 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zf-TFIIB PF13453.6 ORY28727.1 - 0.025 13.9 0.3 0.025 13.9 0.3 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-C2H2_9 PF16293.5 ORY28727.1 - 0.036 13.9 0.4 3 7.8 0.1 2.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) YabA PF06156.13 ORY28727.1 - 0.67 10.6 3.0 1.6 9.4 0.6 2.8 2 1 0 2 2 2 0 Initiation control protein YabA zf-C2H2 PF00096.26 ORY28727.1 - 4.2 8.0 13.2 0.97 10.0 0.2 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY28727.1 - 6.4 7.9 22.3 2.3 9.3 0.1 5.7 5 1 1 6 6 6 0 C2H2-type zinc finger Peptidase_M36 PF02128.15 ORY28728.1 - 2.1e-150 501.0 0.8 3.4e-150 500.3 0.8 1.3 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 ORY28728.1 - 3.3e-06 26.8 0.2 7.6e-06 25.7 0.2 1.7 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 ORY28728.1 - 0.0008 19.3 0.0 0.0021 18.0 0.0 1.7 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Zip PF02535.22 ORY28728.1 - 5.9 6.0 5.7 12 5.0 5.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4330 PF14221.6 ORY28729.1 - 0.33 11.2 2.2 0.88 9.8 2.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) Mod_r PF07200.13 ORY28729.1 - 1.2 9.2 7.3 0.3 11.2 1.3 2.4 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein OrfB_Zn_ribbon PF07282.11 ORY28730.1 - 0.00037 20.4 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Phage_1_1 PF08200.11 ORY28731.1 - 9.7 6.7 7.6 0.81 10.1 2.6 1.9 2 0 0 2 2 2 0 Bacteriophage 1.1 Protein LRR_8 PF13855.6 ORY28733.1 - 4.2e-08 32.8 5.3 0.00028 20.6 0.2 2.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY28733.1 - 3.8e-05 24.0 1.7 0.00034 20.9 0.4 2.7 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY28733.1 - 0.0022 17.9 4.8 0.46 10.7 0.2 3.0 3 0 0 3 3 3 2 Leucine Rich repeat SOG2 PF10428.9 ORY28733.1 - 0.0063 15.8 38.4 0.009 15.3 38.4 1.2 1 0 0 1 1 1 1 RAM signalling pathway protein LRR_1 PF00560.33 ORY28733.1 - 0.039 14.5 0.0 22 6.1 0.1 3.4 3 1 0 3 3 3 0 Leucine Rich Repeat BetR PF08667.10 ORY28733.1 - 0.097 12.7 0.0 0.33 11.0 0.0 1.9 1 0 0 1 1 1 0 BetR domain Utp14 PF04615.13 ORY28733.1 - 0.16 10.6 8.7 0.19 10.2 8.7 1.1 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.9 ORY28733.1 - 0.18 10.4 19.5 0.31 9.5 19.5 1.4 1 0 0 1 1 1 0 Macoilin family SPX PF03105.19 ORY28733.1 - 0.47 10.3 22.2 0.74 9.7 22.2 1.2 1 0 0 1 1 1 0 SPX domain SOBP PF15279.6 ORY28733.1 - 4.4 7.8 17.0 6.6 7.2 17.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Hamartin PF04388.12 ORY28733.1 - 9.3 4.8 33.5 15 4.1 33.5 1.2 1 0 0 1 1 1 0 Hamartin protein DUF572 PF04502.13 ORY28733.1 - 9.8 5.7 18.5 15 5.1 18.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Methyltransf_31 PF13847.6 ORY28734.1 - 7.2e-10 38.9 0.0 1.1e-09 38.2 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY28734.1 - 2.6e-07 31.3 0.0 7.8e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY28734.1 - 2.2e-05 25.0 0.0 6.6e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY28734.1 - 2.9e-05 24.0 0.0 3.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY28734.1 - 3.5e-05 24.5 0.0 6.3e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY28734.1 - 0.00062 19.4 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 ORY28734.1 - 0.007 15.3 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.14 ORY28734.1 - 0.016 14.6 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB PrmA PF06325.13 ORY28734.1 - 0.037 13.4 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AdoMet_MTase PF07757.13 ORY28734.1 - 0.051 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 ORY28734.1 - 0.068 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Mob1_phocein PF03637.17 ORY28735.1 - 4.4e-69 231.8 0.1 5.3e-69 231.6 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family Sec7 PF01369.20 ORY28736.1 - 6.8e-06 25.9 0.1 8.7e-06 25.5 0.1 1.1 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 ORY28737.1 - 0.013 15.9 0.0 0.039 14.3 0.1 1.7 2 0 0 2 2 2 0 Pleckstrin homology domain Pkinase_Tyr PF07714.17 ORY28738.1 - 4.6e-45 153.9 0.0 5.6e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORY28738.1 - 3.6e-38 131.4 0.0 4.5e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 ORY28738.1 - 9.9e-05 21.8 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY28738.1 - 0.002 17.5 0.0 0.0045 16.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORY28738.1 - 0.0042 17.0 0.4 0.0078 16.2 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family HLH PF00010.26 ORY28741.1 - 1.4e-06 28.1 0.4 3.2e-06 27.0 0.4 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MHC2-interact PF09307.10 ORY28742.1 - 0.014 15.4 0.0 0.019 14.9 0.0 1.1 1 0 0 1 1 1 0 CLIP, MHC2 interacting Evr1_Alr PF04777.13 ORY28743.1 - 2e-25 89.2 0.1 2.4e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 Erv1 / Alr family DUF3818 PF12825.7 ORY28745.1 - 7.5e-13 48.2 0.2 5.6e-08 32.2 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) HSR PF03172.13 ORY28745.1 - 0.02 15.0 0.0 0.056 13.6 0.0 1.8 1 0 0 1 1 1 0 HSR domain PX PF00787.24 ORY28746.1 - 2.3e-09 37.2 0.1 5e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 PX domain ubiquitin PF00240.23 ORY28749.1 - 0.00035 20.3 0.0 0.0038 16.9 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin family zf-Di19 PF05605.12 ORY28749.1 - 0.24 11.7 2.9 6.2 7.2 0.4 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding MINDY_DUB PF04424.13 ORY28751.1 - 1.6e-20 73.3 0.3 7.2e-20 71.2 0.0 2.2 2 1 0 2 2 2 1 MINDY deubiquitinase Roughex PF06020.11 ORY28751.1 - 0.015 14.4 6.7 0.02 14.0 6.7 1.2 1 0 0 1 1 1 0 Drosophila roughex protein SOG2 PF10428.9 ORY28752.1 - 0.073 12.3 20.8 0.094 11.9 20.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CPSF100_C PF13299.6 ORY28752.1 - 2.9 8.1 6.6 4.4 7.5 6.6 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RIFIN PF02009.16 ORY28752.1 - 4.8 7.0 14.4 7.6 6.3 14.4 1.2 1 0 0 1 1 1 0 Rifin Plasmodium_Vir PF05795.11 ORY28752.1 - 5.5 6.3 8.1 8 5.8 8.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Stevor PF17410.2 ORY28752.1 - 8.9 5.8 11.0 15 5.0 11.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Nipped-B_C PF12830.7 ORY28753.1 - 0.092 12.7 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus Striatin PF08232.12 ORY28753.1 - 0.83 10.2 4.7 2.4 8.8 1.9 2.5 2 1 0 2 2 2 0 Striatin family CCDC142 PF14923.6 ORY28754.1 - 0.066 12.0 0.1 0.09 11.5 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil protein 142 EcsC PF12787.7 ORY28754.1 - 0.16 11.6 0.6 0.24 11.0 0.6 1.1 1 0 0 1 1 1 0 EcsC protein family CFEM PF05730.11 ORY28755.1 - 0.13 12.4 1.6 0.24 11.5 1.6 1.5 1 1 0 1 1 1 0 CFEM domain Ank_2 PF12796.7 ORY28757.1 - 2.4e-06 28.0 0.8 0.017 15.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY28757.1 - 0.064 13.9 0.1 3.7 8.3 0.0 3.2 3 0 0 3 3 3 0 Ankyrin repeats (many copies) AA_permease_2 PF13520.6 ORY28758.1 - 3.5e-52 177.7 37.1 4.4e-52 177.3 37.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY28758.1 - 4.1e-23 81.7 31.5 7e-23 81.0 31.5 1.4 1 1 0 1 1 1 1 Amino acid permease DUF872 PF05915.12 ORY28758.1 - 7.8 6.7 11.5 2.5 8.3 0.4 3.5 4 0 0 4 4 4 0 Eukaryotic protein of unknown function (DUF872) Nrap_D2 PF17403.2 ORY28884.1 - 1.3e-41 141.9 0.9 3.7e-40 137.2 0.5 2.6 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D5 PF17406.2 ORY28884.1 - 5.5e-41 140.0 0.3 7.2e-40 136.4 0.2 2.5 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 ORY28884.1 - 2.4e-37 128.4 0.0 4.4e-37 127.5 0.0 1.5 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 ORY28884.1 - 1.5e-36 125.7 0.0 3.3e-36 124.6 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D3 PF17404.2 ORY28884.1 - 5.6e-34 117.5 0.1 1.7e-33 115.9 0.0 1.9 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap_D6 PF17407.2 ORY28884.1 - 6.5e-27 94.4 0.5 1.7e-26 93.1 0.5 1.8 1 0 0 1 1 1 1 Nrap protein domain 6 RPA43_OB PF17875.1 ORY28884.1 - 1.7 9.3 8.3 31 5.2 0.0 3.3 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I FtsJ PF01728.19 ORY28885.1 - 9.5e-71 237.5 0.0 1.1e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Phytase-like PF13449.6 ORY28885.1 - 0.04 13.9 0.0 0.051 13.5 0.0 1.1 1 0 0 1 1 1 0 Esterase-like activity of phytase RecQ_Zn_bind PF16124.5 ORY28886.1 - 0.12 13.2 0.0 0.5 11.1 0.0 2.1 2 1 0 2 2 2 0 RecQ zinc-binding TIR_2 PF13676.6 ORY28887.1 - 5.5e-08 33.4 0.0 1.7e-07 31.9 0.0 1.8 1 1 1 2 2 2 1 TIR domain TIR PF01582.20 ORY28887.1 - 0.00031 20.6 0.0 0.00045 20.1 0.0 1.2 1 0 0 1 1 1 1 TIR domain AAA_30 PF13604.6 ORY28887.1 - 0.011 15.4 0.0 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain Nuc_deoxyrib_tr PF05014.15 ORY28887.1 - 0.024 14.7 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase AAA_7 PF12775.7 ORY28887.1 - 0.043 13.3 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 ORY28887.1 - 0.044 14.2 0.0 0.068 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain HR_lesion PF05514.11 ORY28887.1 - 0.049 13.8 0.0 0.082 13.1 0.0 1.3 1 0 0 1 1 1 0 HR-like lesion-inducing PIF1 PF05970.14 ORY28887.1 - 0.078 12.1 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase AAA_19 PF13245.6 ORY28887.1 - 0.1 13.0 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 ORY28887.1 - 0.22 10.7 0.0 0.28 10.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) WD40 PF00400.32 ORY28890.1 - 1.4e-128 415.0 63.3 5.9e-11 42.8 0.4 12.8 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY28890.1 - 4e-44 148.8 14.0 0.00049 20.3 0.0 12.3 1 1 11 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY28890.1 - 1.6e-27 96.4 20.4 0.017 13.8 0.0 11.6 5 4 7 12 12 12 10 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY28890.1 - 6.9e-16 58.4 4.7 0.082 12.2 0.0 7.8 5 2 3 8 8 8 6 WD40-like domain Ge1_WD40 PF16529.5 ORY28890.1 - 1.8e-09 37.0 32.6 0.17 10.8 1.6 10.9 1 1 6 8 8 8 8 WD40 region of Ge1, enhancer of mRNA-decapping protein Polysacc_synt_2 PF02719.15 ORY28890.1 - 3.4e-08 33.0 2.5 0.35 10.0 0.0 4.5 5 0 0 5 5 5 3 Polysaccharide biosynthesis protein Plavaka PF18759.1 ORY28890.1 - 2.6e-05 23.6 0.0 12 4.9 0.0 5.4 3 2 1 6 6 6 1 Plavaka transposase NACHT PF05729.12 ORY28890.1 - 0.0041 17.0 0.2 0.012 15.6 0.2 1.7 1 1 0 1 1 1 1 NACHT domain Rav1p_C PF12234.8 ORY28891.1 - 9.4e-157 523.2 1.2 9.4e-157 523.2 1.2 1.7 2 0 0 2 2 2 1 RAVE protein 1 C terminal WD40 PF00400.32 ORY28891.1 - 6.7e-05 23.6 8.1 0.25 12.3 0.1 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY28891.1 - 0.01 16.1 0.1 2.2 8.7 0.0 4.1 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF5522 PF17653.1 ORY28892.1 - 2.3e-18 65.9 9.7 4.7e-18 64.9 9.7 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5522) Diphthami_syn_2 PF01902.17 ORY28892.1 - 4.4e-06 26.4 0.0 6.8e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Diphthamide synthase Peripla_BP_2 PF01497.18 ORY28892.1 - 4.6e-06 26.4 0.0 8.7e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein Radical_SAM PF04055.21 ORY28892.1 - 0.068 13.6 0.0 0.22 11.9 0.0 1.8 2 0 0 2 2 2 0 Radical SAM superfamily ApoA-II PF04711.13 ORY28892.1 - 0.17 12.0 0.1 0.57 10.4 0.0 1.9 2 0 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) tRNA-synt_2d PF01409.20 ORY28893.1 - 6e-90 301.0 0.0 9.1e-90 300.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 ORY28893.1 - 1.1e-16 60.8 0.1 1.1e-16 60.8 0.1 2.1 3 0 0 3 3 3 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 ORY28893.1 - 1.4e-09 37.8 0.0 1.2e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2b PF00587.25 ORY28893.1 - 1.8e-05 24.8 0.0 3.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 ORY28893.1 - 0.0036 16.4 0.5 0.018 14.2 0.1 2.3 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) PheRS_DBD1 PF18552.1 ORY28893.1 - 0.036 13.8 0.0 0.092 12.5 0.0 1.8 1 0 0 1 1 1 0 PheRS DNA binding domain 1 S10_plectin PF03501.15 ORY28893.1 - 0.15 12.2 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Plectin/S10 domain ABC_membrane PF00664.23 ORY28894.1 - 5.5e-60 203.3 34.2 4.4e-32 111.8 12.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY28894.1 - 1.9e-56 190.4 0.0 2e-32 112.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY28894.1 - 7.9e-12 45.1 4.4 0.0019 17.7 0.0 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY28894.1 - 1.1e-08 35.1 0.7 0.0034 17.4 0.1 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY28894.1 - 7.7e-08 32.0 0.5 0.012 15.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 ORY28894.1 - 6.3e-07 29.6 1.4 0.0018 18.4 0.7 2.8 2 0 0 2 2 2 2 Dynamin family AAA_16 PF13191.6 ORY28894.1 - 7.6e-07 29.7 0.2 0.031 14.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 ORY28894.1 - 9.6e-07 28.9 0.3 0.11 12.3 0.0 3.8 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORY28894.1 - 3.8e-06 26.9 1.4 0.0025 17.7 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 ORY28894.1 - 3.8e-05 24.3 2.7 0.14 12.6 0.2 2.9 3 0 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.18 ORY28894.1 - 0.00017 21.1 0.4 0.38 10.1 0.0 2.2 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF87 PF01935.17 ORY28894.1 - 0.0002 21.5 2.8 0.063 13.4 0.1 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 ORY28894.1 - 0.00047 19.2 0.1 0.73 8.7 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_15 PF13175.6 ORY28894.1 - 0.00083 19.2 0.0 0.37 10.5 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.12 ORY28894.1 - 0.0015 18.5 0.4 3.1 7.7 0.0 3.0 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 ORY28894.1 - 0.0015 18.8 1.2 1.5 9.1 0.1 2.9 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 ORY28894.1 - 0.0017 17.5 0.0 0.33 10.0 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 ORY28894.1 - 0.0021 17.6 0.1 2.4 7.7 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region cobW PF02492.19 ORY28894.1 - 0.0023 17.5 1.0 0.23 11.1 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 ORY28894.1 - 0.003 16.8 1.5 1.4 8.0 0.1 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_30 PF13604.6 ORY28894.1 - 0.0035 17.1 0.3 2.1 8.0 0.1 3.0 3 0 0 3 3 3 1 AAA domain KAP_NTPase PF07693.14 ORY28894.1 - 0.004 16.4 0.1 0.29 10.3 0.0 2.3 2 0 0 2 2 2 1 KAP family P-loop domain Zeta_toxin PF06414.12 ORY28894.1 - 0.01 15.1 0.2 0.76 9.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin DUF815 PF05673.13 ORY28894.1 - 0.018 14.2 0.1 2.4 7.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Roc PF08477.13 ORY28894.1 - 0.021 15.1 0.3 3.6 7.8 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 ORY28894.1 - 0.083 12.3 0.3 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AIG1 PF04548.16 ORY28894.1 - 0.22 10.8 2.6 2.6 7.3 0.3 2.4 2 0 0 2 2 2 0 AIG1 family RNA_helicase PF00910.22 ORY28894.1 - 0.22 11.9 0.4 32 5.0 0.0 3.3 3 0 0 3 3 2 0 RNA helicase OPT PF03169.15 ORY28895.1 - 2.9e-125 419.3 48.6 3.4e-125 419.1 48.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2109 PF09882.9 ORY28895.1 - 0.69 10.0 10.1 0.31 11.1 1.0 3.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2109) KH_8 PF17903.1 ORY28896.1 - 4.5e-31 106.8 0.0 8.6e-31 105.9 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 ORY28896.1 - 0.013 15.3 0.0 0.033 14.0 0.0 1.7 1 1 1 2 2 2 0 KH domain Dscam_C PF12355.8 ORY28896.1 - 0.021 15.8 0.5 0.043 14.8 0.5 1.5 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal UTP25 PF06862.12 ORY28897.1 - 2.4e-172 574.0 1.8 6.6e-160 533.0 0.1 2.1 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 ORY28897.1 - 0.00035 20.4 0.1 0.69 9.6 0.0 2.4 2 1 0 2 2 2 2 DEAD/DEAH box helicase TFIIA PF03153.13 ORY28897.1 - 0.0014 18.8 21.1 0.0018 18.4 21.1 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RNA_pol_3_Rpc31 PF11705.8 ORY28897.1 - 1.3 9.3 35.8 2.6 8.2 35.8 1.6 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SAPS PF04499.15 ORY28897.1 - 2.5 6.8 11.0 4.9 5.8 11.0 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Lipase_GDSL_2 PF13472.6 ORY28899.1 - 1.7e-20 74.2 0.0 2.3e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY28899.1 - 2.1e-09 37.6 0.0 3.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SNARE PF05739.19 ORY28901.1 - 0.00052 20.0 4.6 0.00085 19.3 4.4 1.5 1 1 0 1 1 1 1 SNARE domain Use1 PF09753.9 ORY28901.1 - 0.029 14.1 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 LNS2 PF08235.13 ORY28904.1 - 4.6e-73 245.4 0.4 3.3e-71 239.4 0.4 2.2 1 1 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_mid PF16876.5 ORY28904.1 - 3.7e-11 43.1 0.0 2e-10 40.7 0.0 2.2 2 0 0 2 2 2 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Lipin_N PF04571.14 ORY28904.1 - 0.0012 18.8 0.0 0.0034 17.3 0.0 1.9 1 0 0 1 1 1 1 lipin, N-terminal conserved region GBR2_CC PF18455.1 ORY28904.1 - 0.016 15.3 0.1 0.044 13.9 0.1 1.7 1 0 0 1 1 1 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain GMC_oxred_N PF00732.19 ORY28905.1 - 1.8e-36 126.1 5.5 3.7e-23 82.4 0.2 2.7 2 1 1 3 3 3 2 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY28905.1 - 1.5e-24 87.1 0.1 2.6e-24 86.4 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 ORY28905.1 - 6e-10 38.8 1.0 0.00028 20.2 0.1 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY28905.1 - 2.9e-09 36.5 7.6 1.6e-08 34.0 6.0 2.4 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.24 ORY28905.1 - 2.5e-05 24.1 3.6 0.029 14.0 2.0 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY28905.1 - 4.7e-05 23.5 0.4 0.00017 21.7 0.4 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ORY28905.1 - 8.9e-05 21.9 0.1 0.00017 21.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ORY28905.1 - 0.00019 20.7 0.7 0.0012 18.0 0.0 2.4 2 1 1 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.27 ORY28905.1 - 0.00026 21.5 1.3 0.0069 16.9 0.3 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY28905.1 - 0.00032 20.0 1.8 0.00041 19.7 0.5 1.8 2 0 0 2 2 2 1 Thi4 family ApbA PF02558.16 ORY28905.1 - 0.00072 19.2 0.1 0.0013 18.4 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 ORY28905.1 - 0.0059 15.7 0.6 0.013 14.6 0.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 ORY28905.1 - 0.006 15.3 1.9 0.006 15.3 1.9 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 ORY28905.1 - 0.0068 15.7 0.1 0.037 13.3 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORY28905.1 - 0.02 14.3 3.2 0.02 14.3 3.2 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 ORY28905.1 - 0.042 13.7 0.2 0.074 12.9 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 ORY28905.1 - 0.064 13.5 0.8 0.1 12.8 0.1 1.7 2 0 0 2 2 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 ORY28905.1 - 0.1 12.1 0.2 0.23 11.0 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.21 ORY28905.1 - 0.12 11.8 1.1 0.27 10.5 1.1 1.6 1 0 0 1 1 1 0 ThiF family YjeF_N PF03853.15 ORY28905.1 - 0.35 10.7 2.2 2.9 7.7 0.4 2.8 2 1 1 3 3 3 0 YjeF-related protein N-terminus RPAP3_C PF13877.6 ORY28911.1 - 7.7e-15 55.2 0.0 2e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.28 ORY28911.1 - 7.2e-13 47.8 9.3 8e-05 22.3 0.2 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY28911.1 - 4.4e-07 29.5 11.2 0.0064 16.5 0.2 4.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY28911.1 - 0.0038 17.2 0.2 1.2 9.4 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY28911.1 - 0.0041 17.4 7.3 0.22 11.8 2.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY28911.1 - 0.0046 17.6 0.3 0.0046 17.6 0.3 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY28911.1 - 0.017 15.3 1.3 3.1 8.2 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY28911.1 - 0.094 12.4 0.1 0.26 11.0 0.1 1.8 1 0 0 1 1 1 0 TPR repeat TPR_17 PF13431.6 ORY28911.1 - 0.23 11.9 1.4 0.96 10.0 0.2 2.8 3 1 0 3 3 3 0 Tetratricopeptide repeat RINGv PF12906.7 ORY28912.1 - 0.02 15.0 10.9 0.035 14.2 10.9 1.4 1 0 0 1 1 1 0 RING-variant domain Glyco_transf_8 PF01501.20 ORY28912.1 - 0.032 13.8 0.8 2 7.9 0.2 2.8 2 1 0 2 2 2 0 Glycosyl transferase family 8 WD40 PF00400.32 ORY28914.1 - 3.3e-40 135.3 13.8 5.9e-10 39.6 0.1 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY28914.1 - 5.2e-15 55.5 2.2 0.00016 21.9 0.1 4.4 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY28914.1 - 0.00014 21.3 1.3 0.059 12.7 0.1 2.4 2 1 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 ORY28914.1 - 0.00092 18.3 0.1 0.25 10.2 0.1 2.4 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Utp8 PF10395.9 ORY28914.1 - 0.0016 17.0 0.2 0.01 14.4 0.0 2.0 2 0 0 2 2 2 1 Utp8 family Nup160 PF11715.8 ORY28914.1 - 0.0052 15.5 3.3 0.23 10.1 0.1 2.9 1 1 2 3 3 3 2 Nucleoporin Nup120/160 CNH PF00780.22 ORY28914.1 - 0.011 15.4 0.2 0.12 12.0 0.1 2.4 2 1 1 3 3 3 0 CNH domain DUF4402 PF14352.6 ORY28914.1 - 0.054 14.1 0.3 5.9 7.6 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4402) Choline_sulf_C PF12411.8 ORY28914.1 - 5.9 6.8 8.6 21 5.0 0.3 4.2 6 0 0 6 6 6 0 Choline sulfatase enzyme C terminal Ank_2 PF12796.7 ORY28915.1 - 2e-24 86.0 0.0 3e-09 37.3 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY28915.1 - 1.2e-13 49.8 1.0 0.26 12.0 0.0 8.4 9 0 0 9 9 9 3 Ankyrin repeat Ank_4 PF13637.6 ORY28915.1 - 1.3e-13 51.2 0.7 0.025 15.2 0.2 5.4 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY28915.1 - 3e-10 40.2 3.2 0.0076 16.5 0.0 6.4 2 2 4 6 6 6 1 Ankyrin repeats (many copies) Ank PF00023.30 ORY28915.1 - 5.6e-09 36.0 0.2 0.00022 21.5 0.0 5.3 4 1 1 5 5 5 1 Ankyrin repeat F-box-like PF12937.7 ORY28915.1 - 0.0014 18.4 0.4 0.005 16.7 0.0 2.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 ORY28915.1 - 0.016 15.1 0.1 0.042 13.7 0.1 1.8 1 0 0 1 1 1 0 F-box domain DUF3474 PF11960.8 ORY28916.1 - 0.014 15.6 0.9 0.016 15.4 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) Mucin PF01456.17 ORY28916.1 - 0.018 15.1 24.2 0.022 14.7 24.2 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF4366 PF14283.6 ORY28916.1 - 0.056 13.5 10.4 0.61 10.1 10.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) TIP41 PF04176.13 ORY28916.1 - 0.24 10.9 2.7 0.29 10.6 2.7 1.1 1 0 0 1 1 1 0 TIP41-like family DUF5305 PF17231.2 ORY28916.1 - 0.37 10.1 2.2 0.79 9.1 2.2 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5305) Sec10 PF07393.11 ORY28916.1 - 0.46 8.9 6.5 0.5 8.7 6.5 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec10 Pex14_N PF04695.13 ORY28916.1 - 0.9 10.2 16.3 1.4 9.6 16.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Lipase_3 PF01764.25 ORY28918.1 - 4e-16 59.2 0.0 9.7e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 ORY28918.1 - 0.00018 21.1 0.0 0.00064 19.4 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 ORY28918.1 - 0.023 15.3 0.0 0.048 14.3 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family NVEALA PF14055.6 ORY28918.1 - 0.042 13.8 0.2 0.14 12.1 0.2 1.9 1 0 0 1 1 1 0 NVEALA protein PGAP1 PF07819.13 ORY28918.1 - 0.048 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Mrpl_C PF18502.1 ORY28918.1 - 0.2 11.9 3.1 0.18 12.1 1.3 1.8 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain RYDR_ITPR PF01365.21 ORY28919.1 - 1.7e-27 96.2 4.1 4e-16 59.0 0.0 4.0 3 1 0 3 3 3 2 RIH domain Ins145_P3_rec PF08709.11 ORY28919.1 - 7.8e-25 87.3 0.0 2.1e-20 72.9 0.0 2.8 3 0 0 3 3 3 2 Inositol 1,4,5-trisphosphate/ryanodine receptor RIH_assoc PF08454.11 ORY28919.1 - 5.8e-22 77.4 8.8 1.3e-20 73.2 1.2 5.8 5 0 0 5 5 5 1 RyR and IP3R Homology associated MIR PF02815.19 ORY28919.1 - 7.9e-16 58.4 0.0 2.2e-13 50.5 0.0 3.3 2 0 0 2 2 2 1 MIR domain Ion_trans PF00520.31 ORY28919.1 - 4.5e-13 49.0 4.2 1.1e-12 47.7 4.2 1.7 1 0 0 1 1 1 1 Ion transport protein STAR_dimer PF16544.5 ORY28919.1 - 0.94 9.1 3.3 7.2 6.3 1.1 3.0 2 0 0 2 2 2 0 Homodimerisation region of STAR domain protein LRR_4 PF12799.7 ORY28920.1 - 0.0018 18.7 10.4 0.024 15.1 2.1 3.0 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY28920.1 - 0.022 14.8 0.1 5.3 7.4 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.6 ORY28920.1 - 0.18 11.6 7.1 0.55 10.0 1.7 3.1 1 1 2 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 ORY28921.1 - 0.0037 17.6 10.1 0.0091 16.4 3.7 6.0 4 2 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY28921.1 - 0.021 14.6 17.6 0.49 10.2 1.0 4.8 3 1 3 6 6 6 0 Leucine rich repeat LRR_1 PF00560.33 ORY28921.1 - 0.31 11.7 15.9 1.3e+02 3.8 0.3 7.1 5 2 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 ORY28921.1 - 0.87 9.8 12.7 2.9 8.2 0.0 6.6 8 0 0 8 8 8 0 Leucine Rich repeat Peroxidase_ext PF11895.8 ORY28921.1 - 2.1 8.4 11.3 23 5.0 0.0 5.3 5 0 0 5 5 5 0 Fungal peroxidase extension region PAP2 PF01569.21 ORY28922.1 - 3e-12 46.5 11.9 1.1e-11 44.7 8.0 2.7 2 1 0 2 2 2 1 PAP2 superfamily DUF962 PF06127.11 ORY28922.1 - 0.0048 17.0 1.7 0.029 14.5 0.9 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF212 PF02681.14 ORY28922.1 - 0.087 13.0 6.3 0.095 12.8 0.5 2.7 1 1 0 2 2 2 0 Divergent PAP2 family FeoB_C PF07664.12 ORY28922.1 - 1.1 9.0 4.5 2.9 7.6 0.0 3.3 4 0 0 4 4 4 0 Ferrous iron transport protein B C terminus Caps_synth_CapC PF14102.6 ORY28922.1 - 1.9 9.0 7.4 3.6 8.0 0.3 2.3 2 0 0 2 2 2 0 Capsule biosynthesis CapC Tmemb_18A PF09771.9 ORY28922.1 - 2.4 8.6 4.8 0.61 10.5 0.2 2.2 3 0 0 3 3 3 0 Transmembrane protein 188 Transmemb_17 PF09799.9 ORY28922.1 - 7.5 7.2 8.8 1.4 9.6 0.2 2.9 2 1 1 3 3 3 0 Predicted membrane protein Sulfotransfer_1 PF00685.27 ORY28923.1 - 2e-43 148.8 0.7 2.6e-43 148.4 0.7 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 ORY28923.1 - 2e-06 28.4 0.9 0.0015 19.0 0.4 2.5 1 1 1 2 2 2 2 Sulfotransferase family Amino_oxidase PF01593.24 ORY28924.1 - 1.1e-69 235.9 0.0 4.9e-69 233.8 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY28924.1 - 2.8e-16 59.5 0.0 5.9e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY28924.1 - 7.6e-08 32.3 0.2 1.1e-05 25.2 0.4 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 ORY28924.1 - 1e-07 31.5 0.0 9.8e-07 28.2 0.1 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 ORY28924.1 - 3e-07 29.9 0.1 5e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ORY28924.1 - 8.1e-07 28.7 0.0 1.1e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY28924.1 - 4.2e-06 25.7 0.2 6.5e-06 25.1 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 ORY28924.1 - 1.1e-05 24.9 0.1 0.0018 17.6 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY28924.1 - 4.5e-05 23.9 0.1 0.0004 20.9 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY28924.1 - 6.5e-05 22.3 0.0 0.00013 21.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY28924.1 - 6.6e-05 22.3 0.1 0.00012 21.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 ORY28924.1 - 0.00025 20.3 0.0 0.00035 19.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 ORY28924.1 - 0.00089 18.4 0.6 0.0013 17.9 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein K_oxygenase PF13434.6 ORY28924.1 - 0.0057 15.8 0.0 1.3 8.1 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 ORY28924.1 - 0.089 12.1 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ORY28925.1 - 2.6e-102 341.0 0.1 3.3e-102 340.7 0.1 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 ORY28925.1 - 9.6e-09 35.3 1.7 1.9e-08 34.3 1.5 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY28925.1 - 7.4e-08 32.5 0.1 1.7e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY28925.1 - 8.7e-07 28.5 0.1 1.2e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY28925.1 - 3.3e-06 26.4 0.7 5.3e-06 25.7 0.7 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 ORY28925.1 - 9.9e-06 24.9 2.6 1.6e-05 24.2 1.7 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 ORY28925.1 - 0.00031 19.6 1.0 0.00045 19.0 1.0 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 ORY28925.1 - 0.00032 20.7 0.4 0.0015 18.5 0.1 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 ORY28925.1 - 0.0025 17.2 0.2 0.0036 16.7 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY28925.1 - 0.0028 16.9 0.5 0.0046 16.2 0.5 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY28925.1 - 0.014 14.5 0.7 0.021 13.9 0.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 ORY28925.1 - 0.018 15.6 0.3 0.043 14.4 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MarR_2 PF12802.7 ORY28925.1 - 0.036 14.0 0.0 0.085 12.8 0.0 1.6 1 0 0 1 1 1 0 MarR family Trp_halogenase PF04820.14 ORY28925.1 - 0.041 12.7 0.8 0.062 12.1 0.8 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 ORY28925.1 - 0.043 13.1 0.2 0.064 12.5 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 ORY28925.1 - 0.045 13.0 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase MtN3_slv PF03083.16 ORY28926.1 - 9.1e-30 102.5 12.2 2.7e-20 72.2 2.7 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange DUF1673 PF07895.11 ORY28926.1 - 0.036 13.8 1.1 0.036 13.8 1.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) MtN3_slv PF03083.16 ORY28927.1 - 2.1e-29 101.4 9.6 6.9e-20 70.9 1.8 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange VMA21 PF09446.10 ORY28928.1 - 0.015 15.4 0.2 0.036 14.2 0.2 1.6 1 0 0 1 1 1 0 VMA21-like domain Peptidase_A4 PF01828.17 ORY28930.1 - 0.058 12.9 0.4 0.24 10.9 0.4 2.0 1 1 0 1 1 1 0 Peptidase A4 family EMP24_GP25L PF01105.24 ORY28931.1 - 3.1e-39 134.8 0.1 3.6e-39 134.6 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Uds1 PF15456.6 ORY28931.1 - 0.024 14.8 0.0 0.031 14.5 0.0 1.2 1 0 0 1 1 1 0 Up-regulated During Septation Mobilization_B PF17511.2 ORY28931.1 - 0.055 13.8 0.0 0.079 13.3 0.0 1.2 1 0 0 1 1 1 0 Mobilization protein B DinB_2 PF12867.7 ORY28931.1 - 0.071 13.6 0.0 0.099 13.1 0.0 1.2 1 0 0 1 1 1 0 DinB superfamily CagZ PF09053.10 ORY28931.1 - 0.074 12.7 0.1 2.4 7.7 0.0 2.1 2 0 0 2 2 2 0 CagZ He_PIG PF05345.12 ORY28931.1 - 0.19 11.9 1.0 0.74 10.0 0.1 2.2 2 0 0 2 2 2 0 Putative Ig domain Pkinase PF00069.25 ORY28933.1 - 6e-24 84.8 0.0 1.2e-18 67.5 0.0 2.7 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY28933.1 - 5.1e-23 81.7 0.0 4.7e-18 65.4 0.0 2.9 2 1 1 3 3 3 2 Protein tyrosine kinase APH PF01636.23 ORY28933.1 - 0.00015 21.7 0.2 0.00026 21.0 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY28933.1 - 0.038 13.3 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 ORY28933.1 - 0.047 12.6 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 ORY28933.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 ORY28933.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TAP42 PF04177.12 ORY28934.1 - 2e-82 276.9 4.9 2.3e-82 276.7 4.9 1.0 1 0 0 1 1 1 1 TAP42-like family hNIFK_binding PF12196.8 ORY28935.1 - 0.17 11.4 5.7 0.035 13.6 1.4 2.2 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK WD40 PF00400.32 ORY28936.1 - 4e-73 239.5 27.3 4.7e-10 39.9 0.9 9.0 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY28936.1 - 3.5e-28 97.7 7.6 0.0045 17.3 0.0 7.7 1 1 5 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY28936.1 - 1.6e-17 63.4 14.2 0.026 13.2 0.1 7.3 1 1 5 7 7 7 6 Nucleoporin Nup120/160 TIR_2 PF13676.6 ORY28936.1 - 1.4e-16 61.2 0.0 3e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 TIR domain WD40_like PF17005.5 ORY28936.1 - 3.1e-11 43.2 0.6 0.083 12.2 0.1 5.9 1 1 4 6 6 6 5 WD40-like domain Ge1_WD40 PF16529.5 ORY28936.1 - 1.7e-09 37.1 14.5 0.026 13.5 0.2 7.0 1 1 4 5 5 5 5 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 ORY28936.1 - 0.00011 22.1 0.1 0.00029 20.8 0.1 1.7 1 0 0 1 1 1 1 NACHT domain DUF4597 PF15366.6 ORY28936.1 - 0.00032 20.4 1.3 12 5.7 0.0 5.2 2 1 4 6 6 6 2 Domain of unknown function (DUF4597) TIR PF01582.20 ORY28936.1 - 0.0083 15.9 0.0 0.027 14.3 0.0 2.0 1 0 0 1 1 1 1 TIR domain CNH PF00780.22 ORY28936.1 - 0.02 14.5 0.1 36 3.8 0.0 4.1 4 1 1 5 5 5 0 CNH domain DWNN PF08783.11 ORY28936.1 - 0.039 14.2 0.9 0.14 12.4 0.2 2.3 2 0 0 2 2 2 0 DWNN domain DUF5570 PF17731.1 ORY28936.1 - 2.3 8.3 17.3 13 5.8 0.9 5.2 2 1 4 6 6 6 0 Family of unknown function (DUF5570) BUD22 PF09073.10 ORY28937.1 - 3.2 7.0 14.7 3.8 6.7 14.7 1.1 1 0 0 1 1 1 0 BUD22 IBD PF10416.9 ORY28940.1 - 0.04 13.9 0.3 16 5.5 0.0 2.6 2 0 0 2 2 2 0 Transcription-initiator DNA-binding domain IBD zf-C2H2 PF00096.26 ORY28940.1 - 0.083 13.4 11.5 9.7 6.9 0.6 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type Peptidase_C15 PF01470.17 ORY28940.1 - 0.11 12.7 0.1 18 5.4 0.0 2.3 2 0 0 2 2 2 0 Pyroglutamyl peptidase OrsD PF12013.8 ORY28940.1 - 0.39 11.2 6.2 1.5 9.3 1.8 2.8 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D IBR PF01485.21 ORY28940.1 - 1.6 9.0 9.6 19 5.6 9.6 2.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain RHD3 PF05879.12 ORY29073.1 - 7e-08 31.1 0.1 1.3e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) VWA_2 PF13519.6 ORY29073.1 - 4.4e-07 30.5 0.0 1.2e-06 29.1 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain GBP PF02263.19 ORY29073.1 - 0.00019 20.8 0.5 0.00048 19.5 0.1 1.8 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain DUF4336 PF14234.6 ORY29077.1 - 0.14 11.4 0.0 0.62 9.2 0.0 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4336) DUF4336 PF14234.6 ORY29078.1 - 0.0017 17.6 0.0 0.042 13.0 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) PAN_1 PF00024.26 ORY29080.1 - 0.00022 21.1 10.2 0.22 11.5 0.0 4.8 3 1 1 4 4 4 3 PAN domain PAN_4 PF14295.6 ORY29080.1 - 0.0021 17.9 19.9 0.13 12.2 1.2 5.2 5 0 0 5 5 5 3 PAN domain MANEC PF07502.14 ORY29080.1 - 8.3 6.8 20.2 0.58 10.5 0.2 5.5 6 0 0 6 6 6 0 MANEC domain Gp45_2 PF17470.2 ORY29084.1 - 0.05 13.6 0.5 0.82 9.7 0.1 2.5 2 0 0 2 2 2 0 Phage gene product 45.2 DUF4551 PF15087.6 ORY29084.1 - 0.076 11.8 3.1 0.11 11.3 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) ThrE PF06738.12 ORY29084.1 - 0.23 10.8 0.0 0.37 10.1 0.0 1.2 1 0 0 1 1 1 0 Putative threonine/serine exporter Erf4 PF10256.9 ORY29086.1 - 0.088 12.9 0.1 0.22 11.6 0.1 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Enolase_C PF00113.22 ORY29087.1 - 6.1e-148 491.8 0.3 1.6e-147 490.4 0.1 1.7 2 0 0 2 2 2 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 ORY29087.1 - 8.1e-60 200.7 0.1 1.6e-59 199.7 0.1 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 ORY29087.1 - 4.2e-05 23.2 0.0 9e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Enolase C-terminal domain-like IMS PF00817.20 ORY29087.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 impB/mucB/samB family LRR_8 PF13855.6 ORY29088.1 - 0.006 16.3 0.1 0.016 15.0 0.1 1.7 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 ORY29088.1 - 0.01 16.2 0.7 2.7 8.5 0.1 3.1 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) iPGM_N PF06415.13 ORY29089.1 - 5.6e-77 258.0 0.0 7.4e-77 257.6 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 ORY29089.1 - 7.3e-76 254.8 0.0 8.4e-76 254.6 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 ORY29089.1 - 0.00017 21.1 0.0 0.0062 16.0 0.0 2.4 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 ORY29089.1 - 0.0019 17.9 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase RHSP PF07999.11 ORY29090.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Retrotransposon hot spot protein BLF1 PF17752.1 ORY29090.1 - 0.17 11.2 0.4 0.77 9.0 0.1 1.9 2 0 0 2 2 2 0 Burkholderia lethal factor 1 NB-ARC PF00931.22 ORY29090.1 - 0.17 11.1 0.0 0.38 9.9 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain EST1_DNA_bind PF10373.9 ORY29091.1 - 1.4e-14 54.3 0.0 9.3e-14 51.6 0.0 2.3 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain DUF1387 PF07139.11 ORY29091.1 - 0.052 13.3 7.7 7.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) CCDC106 PF15794.5 ORY29091.1 - 0.58 9.8 4.2 1.5 8.4 0.0 2.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 EST1 PF10374.9 ORY29091.1 - 3.2 8.4 8.7 4.9 7.8 0.0 3.5 2 2 1 3 3 3 0 Telomerase activating protein Est1 Bcl-2 PF00452.19 ORY29092.1 - 0.081 13.6 0.0 0.21 12.3 0.0 1.6 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family DUF1003 PF06210.11 ORY29093.1 - 0.011 15.8 0.0 0.011 15.8 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1003) MHYT PF03707.16 ORY29093.1 - 4.5 7.5 6.9 0.57 10.4 0.8 2.6 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat DUF3682 PF12446.8 ORY29096.1 - 0.015 15.8 1.7 0.015 15.8 1.7 4.5 4 2 1 5 5 5 0 Protein of unknown function (DUF3682) Myc_N PF01056.18 ORY29096.1 - 1.5 8.6 8.6 7 6.4 0.9 2.4 2 0 0 2 2 2 0 Myc amino-terminal region CK2S PF15011.6 ORY29097.1 - 0.0052 16.7 0.6 0.0052 16.7 0.6 2.3 1 1 1 2 2 2 1 Casein Kinase 2 substrate GCN5L1 PF06320.13 ORY29097.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.6 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) PspB PF06667.12 ORY29097.1 - 0.14 12.2 0.6 0.41 10.7 0.0 2.1 2 0 0 2 2 2 0 Phage shock protein B AnfO_nitrog PF09582.10 ORY29097.1 - 0.28 10.5 3.5 0.58 9.5 0.8 2.4 1 1 1 2 2 2 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) FA_hydroxylase PF04116.13 ORY29098.1 - 3.8 7.9 10.4 0.08 13.3 1.7 2.5 3 0 0 3 3 3 0 Fatty acid hydroxylase superfamily Ni_hydr_CYTB PF01292.20 ORY29100.1 - 8.2e-17 61.4 8.8 1.1e-16 61.0 8.8 1.1 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 GST_C_2 PF13410.6 ORY29100.1 - 1.4e-08 34.6 0.0 3.4e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY29100.1 - 5.5e-06 26.5 0.0 1.1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ORY29100.1 - 1.3e-05 25.8 0.1 5.4e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 ORY29100.1 - 0.0011 18.8 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_C_3 PF14497.6 ORY29100.1 - 0.0033 17.6 0.0 0.0067 16.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TIR_2 PF13676.6 ORY29213.1 - 1.3e-16 61.3 0.2 2.2e-14 54.1 0.0 2.5 2 0 0 2 2 2 1 TIR domain Ank_2 PF12796.7 ORY29213.1 - 1.8e-08 34.8 0.0 6.7e-08 33.0 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) NACHT PF05729.12 ORY29213.1 - 1.3e-06 28.5 0.0 3.8e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 NACHT domain Ank_4 PF13637.6 ORY29213.1 - 8.2e-05 23.1 0.0 0.00093 19.7 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY29213.1 - 0.00042 20.5 0.0 0.01 16.1 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY29213.1 - 0.00071 19.9 0.0 0.068 13.8 0.0 3.3 2 0 0 2 2 2 1 Ankyrin repeat AAA_16 PF13191.6 ORY29213.1 - 0.0074 16.7 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain TIR PF01582.20 ORY29213.1 - 0.097 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 TIR domain NB-ARC PF00931.22 ORY29213.1 - 0.11 11.7 0.0 0.46 9.6 0.0 2.1 2 1 0 2 2 2 0 NB-ARC domain ART PF01129.18 ORY29213.1 - 0.15 11.3 0.0 2.4 7.4 0.0 2.2 2 0 0 2 2 2 0 NAD:arginine ADP-ribosyltransferase Zea_mays_MuDR PF05928.11 ORY29214.1 - 4.7 6.8 5.8 8.9 5.9 5.8 1.4 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) Glyco_hydro_16 PF00722.21 ORY29215.1 - 3e-10 39.9 0.1 6.4e-10 38.8 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SH3_12 PF18129.1 ORY29215.1 - 0.2 11.8 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 Xrn1 SH3-like domain Glyco_trans_2_3 PF13632.6 ORY29216.1 - 6.5e-12 45.8 0.0 6.5e-12 45.8 0.0 2.7 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY29216.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 PMP22_Claudin PF00822.20 ORY29216.1 - 0.76 9.6 10.0 0.07 13.0 0.6 2.6 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin family Glyco_trans_2_3 PF13632.6 ORY29217.1 - 3.7e-14 53.1 0.1 1.1e-13 51.5 0.1 1.9 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Zn_clus PF00172.18 ORY29218.1 - 5.1e-19 68.1 22.1 1.2e-10 41.4 7.5 2.1 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 ORY29218.1 - 1.6 9.2 26.7 1.1 9.8 1.9 3.2 1 1 2 3 3 3 0 Dickkopf N-terminal cysteine-rich region GCFC PF07842.12 ORY29219.1 - 2e-67 227.7 5.8 1.9e-35 122.9 5.9 3.3 2 1 0 2 2 2 2 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 ORY29219.1 - 1.2e-14 53.9 3.0 2.5e-14 52.9 3.0 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 ORY29219.1 - 1.4e-07 31.5 1.0 4e-07 30.0 1.0 1.8 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 ORY29219.1 - 0.002 18.5 13.3 0.002 18.5 13.3 2.4 2 0 0 2 2 2 1 Tuftelin interacting protein N terminal DUF4729 PF15866.5 ORY29221.1 - 0.0056 16.0 0.3 0.011 15.1 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4729) Fungal_trans PF04082.18 ORY29222.1 - 5.6e-06 25.6 1.2 7.9e-06 25.1 0.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY29222.1 - 0.0017 18.4 5.2 0.0031 17.6 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_76 PF03663.14 ORY29223.1 - 4.5e-27 95.5 0.6 5.8e-27 95.1 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 ORY29223.1 - 4e-05 22.9 1.0 0.00049 19.3 0.0 2.1 1 1 1 2 2 2 1 Glycosyl Hydrolase Family 88 Glyco_hydro_47 PF01532.20 ORY29223.1 - 0.0046 15.9 0.1 0.29 10.0 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 47 C5-epim_C PF06662.13 ORY29223.1 - 0.039 13.4 1.1 1.6 8.2 0.0 2.3 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Glyco_hydro_76 PF03663.14 ORY29224.1 - 3.9e-08 33.2 0.4 5.1e-06 26.2 0.1 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 Leo1 PF04004.13 ORY29224.1 - 0.31 10.9 0.4 0.59 10.0 0.4 1.4 1 1 0 1 1 1 0 Leo1-like protein Glyco_hydro_76 PF03663.14 ORY29226.1 - 5.3e-24 85.4 6.7 5.9e-24 85.3 6.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Leuk-A4-hydro_C PF09127.11 ORY29226.1 - 0.028 14.5 0.6 0.042 13.9 0.5 1.4 1 1 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal Glyco_hydro_76 PF03663.14 ORY29227.1 - 1.1e-43 150.1 9.2 1.5e-43 149.7 9.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 ORY29227.1 - 0.48 9.4 6.4 1.5 7.8 0.2 3.2 3 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 Solute_trans_a PF03619.16 ORY29228.1 - 2.4e-54 184.6 25.9 8.4e-53 179.6 25.9 2.2 1 1 0 1 1 1 1 Organic solute transporter Ostalpha DUF3636 PF12331.8 ORY29228.1 - 0.18 11.6 1.1 7 6.5 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3636) Glyco_trans_2_3 PF13632.6 ORY29229.1 - 2.3e-31 109.3 10.3 7.1e-31 107.7 10.3 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Ctf8 PF09696.10 ORY29230.1 - 1.1e-07 32.2 1.1 0.00036 20.9 0.1 2.1 1 1 1 2 2 2 2 Ctf8 TPR_12 PF13424.6 ORY29231.1 - 8.6e-44 147.7 0.0 6.3e-17 61.6 0.0 2.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 ORY29231.1 - 3.7e-34 115.6 0.0 1.1e-08 34.6 0.0 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 ORY29231.1 - 1.9e-12 46.3 0.0 0.14 12.2 0.0 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORY29231.1 - 8.2e-12 44.3 0.0 0.009 16.1 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORY29231.1 - 3.2e-11 42.5 0.0 0.14 12.0 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY29231.1 - 7.6e-10 38.2 0.0 0.18 12.0 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORY29231.1 - 5.5e-05 23.6 0.0 1.4 9.9 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.14 ORY29231.1 - 7e-05 23.1 0.0 1.6 9.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY29231.1 - 0.00011 21.8 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 MalT-like TPR region TPR_16 PF13432.6 ORY29231.1 - 0.00047 20.7 0.0 0.65 10.7 0.0 3.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY29231.1 - 0.00061 20.3 0.0 8.4 7.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY29231.1 - 0.0044 17.2 0.0 2.5 8.4 0.0 3.8 1 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 ORY29231.1 - 0.011 15.7 0.0 39 4.4 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY29231.1 - 0.015 15.8 0.0 3.3 8.3 0.0 3.1 2 1 2 4 4 3 0 Tetratricopeptide repeat PPR PF01535.20 ORY29231.1 - 0.16 12.2 0.2 18 5.9 0.0 2.6 2 0 0 2 2 2 0 PPR repeat Dala_Dala_lig_C PF07478.13 ORY29232.1 - 0.084 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus TPR_12 PF13424.6 ORY29233.1 - 3.1e-33 113.9 6.4 3.1e-12 46.6 0.8 4.0 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 ORY29233.1 - 9e-28 95.3 2.9 2e-11 43.4 0.0 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY29233.1 - 2.7e-08 33.3 1.2 0.0044 17.0 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY29233.1 - 1.3e-07 31.2 0.9 0.16 11.8 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY29233.1 - 5e-06 26.3 0.7 0.33 11.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY29233.1 - 8.6e-05 22.4 4.2 0.35 11.1 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY29233.1 - 9.3e-05 22.9 2.0 1.9 9.5 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY29233.1 - 0.032 14.9 2.5 8 7.3 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY29233.1 - 0.063 13.9 1.8 1.5 9.5 0.1 3.5 3 2 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.12 ORY29233.1 - 0.21 12.3 0.3 5.2 7.9 0.0 2.6 2 1 0 2 2 2 0 Sel1 repeat Aminotran_5 PF00266.19 ORY29234.1 - 0.0045 16.0 0.0 0.0056 15.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Ctf8 PF09696.10 ORY29235.1 - 4.4e-09 36.8 2.3 7.3e-05 23.1 1.1 3.1 2 1 0 2 2 2 2 Ctf8 TPR_12 PF13424.6 ORY29236.1 - 1e-70 234.0 0.0 4e-18 65.5 0.0 4.4 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 ORY29236.1 - 5e-52 172.4 0.0 2.9e-12 46.0 0.0 5.5 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 ORY29236.1 - 1.6e-17 62.5 0.3 0.048 13.5 0.0 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORY29236.1 - 4.2e-17 60.9 0.5 0.002 18.2 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 ORY29236.1 - 5.8e-17 60.4 0.0 0.081 13.0 0.0 5.4 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 ORY29236.1 - 2.6e-15 55.2 0.1 0.087 13.0 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY29236.1 - 5.7e-09 35.8 0.0 9e-05 22.0 0.0 2.2 1 1 1 2 2 2 2 MalT-like TPR region TPR_6 PF13174.6 ORY29236.1 - 5.3e-08 33.0 0.1 2.7 8.8 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY29236.1 - 8.2e-08 32.4 0.0 9.6 7.3 0.0 5.4 2 1 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY29236.1 - 5.9e-07 30.0 0.0 0.24 12.1 0.0 5.2 3 2 1 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY29236.1 - 3.4e-06 27.2 0.3 1.1 9.5 0.0 4.8 1 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 ORY29236.1 - 7.6e-06 26.1 0.0 3.1 8.7 0.1 4.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY29236.1 - 7.7e-06 26.3 0.0 1.2 9.6 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.12 ORY29236.1 - 0.00071 19.5 0.1 18 5.5 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORY29236.1 - 0.0073 16.6 0.9 65 4.3 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 ORY29236.1 - 0.045 14.0 1.7 5 7.6 0.1 3.3 3 0 0 3 3 3 0 PPR repeat Aminotran_5 PF00266.19 ORY29237.1 - 4e-05 22.7 0.0 5.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V zf-MYND PF01753.18 ORY29238.1 - 1.1e-09 38.2 10.6 1.8e-09 37.5 10.6 1.4 1 0 0 1 1 1 1 MYND finger AAA_12 PF13087.6 ORY29239.1 - 1.5e-44 152.1 0.0 4.5e-44 150.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORY29239.1 - 9.7e-22 78.0 0.5 1.8e-15 57.5 0.0 3.7 3 1 1 4 4 4 3 AAA domain AAA_19 PF13245.6 ORY29239.1 - 2e-08 34.7 0.1 1.8e-06 28.3 0.0 3.1 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.6 ORY29239.1 - 5.9e-08 32.6 0.1 1.7e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 ORY29239.1 - 1.3e-05 25.3 0.0 3.5e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 ORY29239.1 - 0.0016 18.0 0.0 0.02 14.4 0.0 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 ORY29239.1 - 0.0028 17.9 0.0 0.08 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 ORY29239.1 - 0.0037 17.1 0.0 0.0078 16.1 0.0 1.5 1 0 0 1 1 1 1 Helicase ATPase_2 PF01637.18 ORY29239.1 - 0.012 15.5 0.0 0.081 12.8 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 ORY29239.1 - 0.015 15.0 0.0 2.4 7.8 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Bac_DnaA PF00308.18 ORY29239.1 - 0.14 11.9 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_16 PF13191.6 ORY29239.1 - 0.16 12.4 0.0 0.43 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 ORY29239.1 - 0.16 12.5 0.0 1.6 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 ORY29239.1 - 0.17 10.9 0.1 0.29 10.1 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein FTR1 PF03239.14 ORY29240.1 - 7.9e-44 150.1 4.6 8.9e-31 107.2 0.9 2.6 2 1 0 2 2 2 2 Iron permease FTR1 family DUF4293 PF14126.6 ORY29240.1 - 0.015 15.5 2.7 1.2 9.3 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) DUF3180 PF11377.8 ORY29240.1 - 0.3 11.2 9.5 0.31 11.2 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) FTR1 PF03239.14 ORY29241.1 - 1.3e-57 195.3 4.5 4.7e-36 124.5 0.3 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family DUF3180 PF11377.8 ORY29241.1 - 0.17 12.0 13.1 0.1 12.7 3.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) MgtE PF01769.16 ORY29241.1 - 0.46 10.9 16.2 0.78 10.1 2.8 3.1 3 0 0 3 3 3 0 Divalent cation transporter START PF01852.19 ORY29243.1 - 3.6e-10 39.6 0.0 5.9e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 START domain MOSP_C PF02722.15 ORY29243.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Major Outer Sheath Protein C-terminal domain DUF563 PF04577.14 ORY29244.1 - 1.2e-12 48.5 0.0 2.8e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF563 PF04577.14 ORY29245.1 - 6.7e-13 49.3 0.0 9.2e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF563 PF04577.14 ORY29247.1 - 1e-10 42.1 0.0 2.6e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Aminotran_5 PF00266.19 ORY29248.1 - 0.11 11.4 0.0 9.9 5.0 0.0 2.3 2 0 0 2 2 2 0 Aminotransferase class-V zf-MYND PF01753.18 ORY29252.1 - 2.4e-12 46.7 7.0 4e-12 46.0 7.0 1.3 1 0 0 1 1 1 1 MYND finger FeoA PF04023.14 ORY29252.1 - 0.15 12.4 0.0 0.33 11.2 0.0 1.6 1 0 0 1 1 1 0 FeoA domain zf-C6H2 PF15801.5 ORY29252.1 - 2.1 8.7 5.8 4.6 7.6 5.7 1.7 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding HAGH_C PF16123.5 ORY29253.1 - 1.6e-20 73.4 0.0 2.6e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 ORY29253.1 - 8.6e-08 32.4 6.5 2.6e-07 30.8 6.5 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily BcrAD_BadFG PF01869.20 ORY29253.1 - 0.11 11.9 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Lactamase_B_2 PF12706.7 ORY29253.1 - 0.54 9.7 2.6 2.9 7.4 2.6 2.0 1 1 0 1 1 1 0 Beta-lactamase superfamily domain WD40 PF00400.32 ORY29254.1 - 1.3e-17 63.8 9.9 0.0028 18.4 0.6 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY29254.1 - 8.9e-05 22.7 7.2 0.029 14.7 1.9 3.6 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain SsgA PF04686.12 ORY29254.1 - 0.14 12.1 0.4 0.34 11.0 0.4 1.6 1 0 0 1 1 1 0 Streptomyces sporulation and cell division protein, SsgA Methyltransf_23 PF13489.6 ORY29255.1 - 5.4e-12 45.9 0.0 7.3e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY29255.1 - 9.2e-07 29.4 0.1 9.5e-05 23.0 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY29255.1 - 1.2e-06 29.1 0.0 0.024 15.3 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 ORY29255.1 - 1.9e-06 28.5 0.0 0.011 16.4 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 ORY29255.1 - 0.00011 22.0 0.0 0.037 13.8 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain DNA_pol_A_exo1 PF01612.20 ORY29256.1 - 1.1e-11 44.8 0.0 1.9e-10 40.7 0.0 2.3 2 0 0 2 2 2 1 3'-5' exonuclease OTU PF02338.19 ORY29256.1 - 2.5e-06 28.0 0.1 4.9e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Glyco_transf_17 PF04724.13 ORY29257.1 - 1.9e-106 356.1 0.2 3.6e-106 355.1 0.2 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 17 Glyco_transf_17 PF04724.13 ORY29258.1 - 9.1e-108 360.4 0.0 2.6e-100 335.9 0.0 2.0 1 1 1 2 2 2 2 Glycosyltransferase family 17 Glyco_hydro_76 PF03663.14 ORY29259.1 - 7.1e-43 147.5 9.9 7.1e-43 147.5 9.9 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 Glyco_hydro_47 PF01532.20 ORY29259.1 - 0.035 13.0 0.1 0.11 11.4 0.1 1.7 1 1 0 1 1 1 0 Glycosyl hydrolase family 47 C1_1 PF00130.22 ORY29260.1 - 5.5e-13 48.6 22.4 3e-08 33.4 4.9 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 ORY29260.1 - 0.00026 21.3 16.7 0.025 14.9 7.7 2.4 2 0 0 2 2 2 2 C1 domain C2 PF00168.30 ORY29260.1 - 0.00036 20.8 0.0 0.00091 19.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain PHD PF00628.29 ORY29260.1 - 0.054 13.4 23.1 0.12 12.3 3.9 2.3 2 0 0 2 2 2 0 PHD-finger zf-HC5HC2H_2 PF13832.6 ORY29260.1 - 0.15 12.2 14.0 0.16 12.1 5.6 2.4 2 0 0 2 2 2 0 PHD-zinc-finger like domain Zn_ribbon_17 PF17120.5 ORY29260.1 - 0.16 11.6 16.9 0.2 11.3 6.1 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 ORY29260.1 - 0.24 11.4 18.3 0.42 10.6 2.3 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zf_RING PF16744.5 ORY29260.1 - 0.68 10.1 12.9 1.6 8.9 4.1 2.5 2 0 0 2 2 2 0 KIAA1045 RING finger Cript PF10235.9 ORY29260.1 - 2 9.0 7.5 1 10.0 2.2 2.5 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT Glyco_hydro_26 PF02156.15 ORY29262.1 - 3.9e-07 29.8 4.3 0.006 16.0 0.2 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 Glyco_hydro_76 PF03663.14 ORY29264.1 - 2.7e-52 178.5 11.2 3.6e-52 178.1 11.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Mid2 PF04478.12 ORY29264.1 - 0.016 15.1 0.4 0.028 14.2 0.4 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Glyco_hydro_47 PF01532.20 ORY29264.1 - 0.018 13.9 0.6 1.4 7.7 0.6 2.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 47 DUF2243 PF10002.9 ORY29264.1 - 0.055 13.6 0.0 3.9 7.6 0.0 3.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2243) PPR_2 PF13041.6 ORY29265.1 - 0.0018 18.4 0.1 0.6 10.3 0.0 2.5 2 0 0 2 2 2 2 PPR repeat family SKG6 PF08693.10 ORY29265.1 - 0.021 14.2 1.0 0.021 14.2 1.0 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain PPR PF01535.20 ORY29265.1 - 0.088 13.1 0.2 4.2 7.8 0.0 2.5 2 0 0 2 2 2 0 PPR repeat Beta-APP PF03494.13 ORY29265.1 - 0.12 12.3 2.3 0.39 10.6 2.3 1.9 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Phage_HK97_TLTM PF06120.11 ORY29265.1 - 0.56 9.4 1.2 0.86 8.7 1.2 1.2 1 0 0 1 1 1 0 Tail length tape measure protein Glyco_hydro_76 PF03663.14 ORY29266.1 - 3e-27 96.1 4.3 4.5e-27 95.5 4.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 PPR_2 PF13041.6 ORY29266.1 - 0.0013 18.9 0.1 0.47 10.7 0.0 2.5 2 0 0 2 2 2 2 PPR repeat family PPR PF01535.20 ORY29266.1 - 0.054 13.8 0.2 3.6 8.0 0.0 2.5 2 0 0 2 2 2 0 PPR repeat MGC-24 PF05283.11 ORY29266.1 - 5 7.6 12.0 2.6 8.5 8.9 1.9 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF5472 PF17566.2 ORY29267.1 - 0.097 12.6 0.0 0.33 10.9 0.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5472) Phage_HK97_TLTM PF06120.11 ORY29267.1 - 0.24 10.5 0.4 0.39 9.9 0.4 1.2 1 0 0 1 1 1 0 Tail length tape measure protein TrbL PF04610.14 ORY29267.1 - 9.3 5.9 10.9 3.1 7.5 6.9 2.1 2 1 1 3 3 3 0 TrbL/VirB6 plasmid conjugal transfer protein Glyco_hydro_76 PF03663.14 ORY29268.1 - 4.9e-49 167.8 6.4 7.3e-49 167.2 6.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_127 PF07944.12 ORY29268.1 - 0.013 14.1 0.5 0.047 12.2 0.0 1.9 2 1 1 3 3 3 0 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_9 PF00759.19 ORY29268.1 - 0.065 12.7 2.9 0.22 10.9 0.0 2.3 2 1 1 3 3 3 0 Glycosyl hydrolase family 9 C5-epim_C PF06662.13 ORY29268.1 - 0.1 12.1 1.7 1 8.8 0.1 2.4 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Protocadherin PF08374.11 ORY29268.1 - 0.12 12.4 0.1 0.19 11.7 0.1 1.2 1 0 0 1 1 1 0 Protocadherin Glyco_hydro_88 PF07470.13 ORY29268.1 - 0.23 10.5 14.5 0.66 9.0 7.5 3.8 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Ank_2 PF12796.7 ORY29269.1 - 2.2e-28 98.7 1.5 9.6e-15 54.9 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORY29269.1 - 3.1e-27 93.8 5.1 2e-07 31.1 0.0 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 ORY29269.1 - 4.4e-24 84.5 0.4 2.7e-09 37.4 0.1 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY29269.1 - 6.6e-21 72.2 0.1 7.9e-06 25.8 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 ORY29269.1 - 1.6e-17 63.3 3.8 4.7e-08 33.1 0.4 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) CorA PF01544.18 ORY29270.1 - 6.6e-16 58.5 0.0 5.4e-09 35.8 0.0 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Ribosomal_L6e PF01159.19 ORY29271.1 - 2.5e-35 121.4 0.4 4.3e-35 120.6 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 ORY29271.1 - 4.2e-06 26.9 0.2 1.1e-05 25.6 0.2 1.8 1 0 0 1 1 1 1 Ribosomal protein L6, N-terminal domain DNA_pol_A_exoN PF18305.1 ORY29271.1 - 0.085 13.2 0.1 0.16 12.2 0.1 1.5 1 1 0 1 1 1 0 3' to 5' exonuclease C-terminal domain zf-CCHC_3 PF13917.6 ORY29272.1 - 7.4e-14 51.4 0.8 1.6e-13 50.3 0.8 1.6 1 0 0 1 1 1 1 Zinc knuckle CDC27 PF09507.10 ORY29272.1 - 0.0026 17.2 24.0 0.0029 17.1 24.0 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 zf-CCHC PF00098.23 ORY29272.1 - 0.019 15.0 1.2 0.03 14.4 1.2 1.3 1 0 0 1 1 1 0 Zinc knuckle BUD22 PF09073.10 ORY29272.1 - 0.13 11.6 33.5 0.14 11.4 33.5 1.1 1 0 0 1 1 1 0 BUD22 Macoilin PF09726.9 ORY29272.1 - 2.6 6.5 26.1 2.7 6.5 26.1 1.0 1 0 0 1 1 1 0 Macoilin family Nop14 PF04147.12 ORY29272.1 - 3.6 5.7 31.4 4 5.5 31.4 1.0 1 0 0 1 1 1 0 Nop14-like family Smg8_Smg9 PF10220.9 ORY29272.1 - 4.1 5.6 15.4 4.6 5.4 15.4 1.2 1 0 0 1 1 1 0 Smg8_Smg9 BROMI PF14961.6 ORY29272.1 - 7.3 3.9 5.9 7.8 3.8 5.9 1.2 1 0 0 1 1 1 0 Broad-minded protein Acetyltransf_7 PF13508.7 ORY29273.1 - 0.035 14.5 0.0 0.084 13.3 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_76 PF03663.14 ORY29274.1 - 1.3e-40 140.1 11.2 2.1e-40 139.4 11.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 C5-epim_C PF06662.13 ORY29274.1 - 0.0036 16.8 0.3 3 7.3 0.0 2.7 3 0 0 3 3 3 2 D-glucuronyl C5-epimerase C-terminus DUF4106 PF13388.6 ORY29274.1 - 4.8 6.3 18.7 1.1 8.5 15.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4106) 23S_rRNA_IVP PF05635.11 ORY29276.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.3 1 1 0 1 1 1 0 23S rRNA-intervening sequence protein DZR PF12773.7 ORY29277.1 - 0.006 16.6 1.6 0.011 15.8 1.6 1.4 1 0 0 1 1 1 1 Double zinc ribbon UPF0547 PF10571.9 ORY29277.1 - 0.022 14.9 1.6 0.047 13.8 1.6 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 FOXP-CC PF16159.5 ORY29279.1 - 0.00017 22.2 7.8 0.072 13.7 3.2 2.7 1 1 1 2 2 2 2 FOXP coiled-coil domain DUF629 PF04780.12 ORY29279.1 - 0.0012 17.4 5.4 0.27 9.7 0.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF629) zf_C2H2_ZHX PF18387.1 ORY29279.1 - 0.039 13.6 0.2 0.15 11.7 0.1 2.0 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-LYAR PF08790.11 ORY29279.1 - 0.073 13.0 0.7 1.5 8.8 0.2 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-H2C2_5 PF13909.6 ORY29279.1 - 0.079 12.7 1.7 2.7 7.8 0.5 3.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zinc_ribbon_5 PF13719.6 ORY29279.1 - 0.19 11.5 2.1 6.9 6.5 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2 PF00096.26 ORY29279.1 - 1 9.9 16.0 4.4 7.9 0.6 5.3 5 2 0 5 5 5 0 Zinc finger, C2H2 type zf_ZIC PF18366.1 ORY29279.1 - 1.2 9.3 4.9 51 4.1 0.0 3.4 3 0 0 3 3 3 0 Zic proteins zinc finger domain zf-C2H2_4 PF13894.6 ORY29279.1 - 2.7 9.0 16.8 2 9.4 1.4 4.8 5 0 0 5 5 5 0 C2H2-type zinc finger zf_ZIC PF18366.1 ORY29280.1 - 0.00023 21.2 0.1 0.0019 18.3 0.0 2.3 2 0 0 2 2 2 1 Zic proteins zinc finger domain zf-C2H2_4 PF13894.6 ORY29280.1 - 0.034 15.0 17.2 0.27 12.2 4.5 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY29280.1 - 0.039 14.4 1.1 0.039 14.4 1.1 4.1 4 1 0 4 4 4 0 Zinc-finger double domain zf-C2H2_8 PF15909.5 ORY29280.1 - 0.058 13.7 3.1 0.12 12.6 3.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc ribbon Actin_micro PF17003.5 ORY29280.1 - 1.7 7.8 5.8 1.1 8.4 4.2 1.4 1 1 0 1 1 1 0 Putative actin-like family zf-C2H2 PF00096.26 ORY29280.1 - 2.2 8.9 22.3 2.6 8.7 0.1 4.3 4 1 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY29282.1 - 0.017 15.9 12.8 2.7 9.1 2.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 ORY29282.1 - 0.19 12.1 6.0 0.51 10.7 6.0 1.8 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf_ZIC PF18366.1 ORY29282.1 - 0.26 11.4 7.6 0.37 10.9 0.0 3.3 3 1 0 3 3 3 0 Zic proteins zinc finger domain FOXP-CC PF16159.5 ORY29282.1 - 1.9 9.2 0.1 1.9 9.2 0.1 2.9 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 ORY29282.1 - 3.7 8.2 15.2 4.6 7.9 3.2 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 ORY29283.1 - 0.0016 18.7 0.3 0.0078 16.5 0.3 2.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) DZR PF12773.7 ORY29283.1 - 0.12 12.4 0.7 0.26 11.3 0.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2 PF00096.26 ORY29283.1 - 0.28 11.7 9.8 23 5.7 1.4 4.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type UvrB PF12344.8 ORY29283.1 - 3.7 7.5 5.1 0.97 9.3 0.2 2.3 2 0 0 2 2 2 0 Ultra-violet resistance protein B zf-LYAR PF08790.11 ORY29284.1 - 0.42 10.6 4.2 0.23 11.4 0.7 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Amelin PF05111.12 ORY29286.1 - 0.074 12.2 1.5 0.1 11.8 1.5 1.1 1 0 0 1 1 1 0 Ameloblastin precursor (Amelin) zf_ZIC PF18366.1 ORY29286.1 - 0.092 12.9 0.3 0.29 11.3 0.0 1.9 2 0 0 2 2 2 0 Zic proteins zinc finger domain cNMP_binding PF00027.29 ORY29288.1 - 4.7e-13 49.0 0.1 3.7e-07 30.1 0.0 2.8 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain TMEM70 PF06979.12 ORY29289.1 - 0.13 12.7 0.0 0.21 12.0 0.0 1.4 1 0 0 1 1 1 0 Assembly, mitochondrial proton-transport ATP synth complex TMEM223 PF14640.6 ORY29289.1 - 0.16 12.1 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 223 TFIIA PF03153.13 ORY29290.1 - 5.8 6.8 14.1 8.3 6.3 14.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRR_8 PF13855.6 ORY29291.1 - 3.2e-10 39.6 17.4 9.3e-06 25.3 5.8 3.9 2 1 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 ORY29291.1 - 7.8e-07 29.3 18.5 0.0048 17.3 5.8 4.3 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY29291.1 - 0.065 13.8 0.4 0.065 13.8 0.4 6.1 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 ORY29291.1 - 0.21 11.8 16.9 2 8.7 0.4 5.1 5 1 0 5 5 5 0 Leucine Rich repeat Mg_trans_NIPA PF05653.14 ORY29293.1 - 7.4e-68 228.8 21.1 9.1e-68 228.5 21.1 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORY29293.1 - 0.00033 20.8 31.3 0.0018 18.4 4.0 4.2 3 1 1 4 4 4 2 EamA-like transporter family BCLP PF12304.8 ORY29293.1 - 0.15 11.6 0.3 0.15 11.6 0.3 3.4 3 1 0 4 4 4 0 Beta-casein like protein Neurensin PF14927.6 ORY29293.1 - 2.9 7.6 7.4 0.6 9.8 0.3 2.7 2 1 0 2 2 2 0 Neurensin B12D PF06522.11 ORY29293.1 - 6.7 6.6 7.7 0.25 11.2 0.5 2.4 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit DctQ PF04290.12 ORY29293.1 - 8.9 6.2 18.6 0.09 12.7 1.1 4.2 2 2 3 5 5 5 0 Tripartite ATP-independent periplasmic transporters, DctQ component Ribosomal_S24e PF01282.19 ORY29409.1 - 0.036 14.0 0.0 0.045 13.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S24e DUF4271 PF14093.6 ORY29410.1 - 0.0017 18.3 6.0 0.0045 16.9 5.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4271) Lung_7-TM_R PF06814.13 ORY29410.1 - 0.025 13.8 2.3 0.047 12.9 1.0 2.1 1 1 2 3 3 3 0 Lung seven transmembrane receptor Holin_BhlA PF10960.8 ORY29410.1 - 0.036 14.0 2.1 0.18 11.8 0.0 2.5 2 1 1 3 3 3 0 BhlA holin family Polysacc_synt_C PF14667.6 ORY29410.1 - 0.33 11.0 7.0 6.7 6.8 0.8 2.2 1 1 1 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Orn_Arg_deC_N PF02784.16 ORY29411.1 - 6.7e-78 261.5 0.0 8.8e-78 261.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 ORY29411.1 - 2.2e-21 75.9 0.0 3.1e-21 75.4 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DUF913 PF06025.12 ORY29411.1 - 0.0014 17.7 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) LRR_9 PF14580.6 ORY29413.1 - 5e-15 55.4 0.3 7.9e-15 54.8 0.3 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 ORY29413.1 - 1.6e-07 31.0 4.5 2.4e-07 30.4 1.2 2.7 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 ORY29413.1 - 2.2e-06 27.9 7.7 0.00031 21.1 1.3 3.7 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) DUF3966 PF13110.6 ORY29413.1 - 0.091 12.7 0.2 0.22 11.4 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3966) TIM PF00121.18 ORY29414.1 - 4.8e-81 271.7 1.8 8e-80 267.7 1.8 1.9 1 1 0 1 1 1 1 Triosephosphate isomerase Lactamase_B_4 PF13691.6 ORY29415.1 - 5.8e-11 41.9 0.0 1.3e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 ORY29415.1 - 3.1e-06 26.8 0.0 6.8e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Mg_chelatase PF01078.21 ORY29415.1 - 0.014 14.8 0.0 0.033 13.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2597 PF10772.9 ORY29415.1 - 0.065 13.3 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) FlaG PF03646.15 ORY29416.1 - 0.29 11.3 1.5 8.8 6.6 0.1 2.4 1 1 1 2 2 2 0 FlaG protein DUF2105 PF09878.9 ORY29418.1 - 0.00098 18.9 2.8 0.0015 18.3 2.8 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2105) ADH_zinc_N_2 PF13602.6 ORY29419.1 - 1.7e-16 61.5 0.1 4.8e-16 60.0 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY29419.1 - 7.7e-09 35.4 0.0 1.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY29419.1 - 2.9e-06 27.3 1.2 3.5e-05 23.8 0.4 2.3 1 1 1 2 2 2 1 Zinc-binding dehydrogenase YtxH PF12732.7 ORY29419.1 - 0.04 14.5 0.1 0.069 13.7 0.1 1.4 1 0 0 1 1 1 0 YtxH-like protein Homeodomain PF00046.29 ORY29420.1 - 6.7e-15 54.7 0.1 1.5e-14 53.6 0.1 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY29420.1 - 0.00015 21.6 0.0 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain Activator_LAG-3 PF11498.8 ORY29420.1 - 0.099 11.6 0.5 0.14 11.1 0.5 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 META PF03724.16 ORY29421.1 - 0.34 10.9 2.7 0.39 10.7 0.5 2.1 2 0 0 2 2 2 0 META domain FHA PF00498.26 ORY29422.1 - 2e-16 60.1 0.0 4e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 ORY29422.1 - 1.3e-09 38.2 0.0 3e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain dsrm PF00035.26 ORY29422.1 - 2.2e-08 34.7 0.6 8e-08 32.9 0.0 2.4 2 0 0 2 2 2 1 Double-stranded RNA binding motif Dicer_dimer PF03368.14 ORY29422.1 - 0.0097 16.0 0.0 0.031 14.4 0.0 1.9 2 0 0 2 2 2 1 Dicer dimerisation domain NAD_binding_2 PF03446.15 ORY29426.1 - 3.9e-13 49.9 0.2 5.5e-13 49.4 0.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ORY29426.1 - 1e-11 45.1 0.0 2.1e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase L31 PF09784.9 ORY29427.1 - 2.4e-23 82.5 0.6 2.9e-23 82.2 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 HSP70 PF00012.20 ORY29428.1 - 2.9e-88 296.6 22.5 1.6e-84 284.3 14.5 2.4 1 1 1 2 2 2 2 Hsp70 protein NDC10_II PF16787.5 ORY29429.1 - 0.00075 18.6 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Nop14 PF04147.12 ORY29429.1 - 0.0047 15.2 11.3 0.0079 14.5 11.3 1.2 1 0 0 1 1 1 1 Nop14-like family DUF2796 PF10986.8 ORY29429.1 - 0.013 15.5 0.3 0.03 14.3 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) YL1 PF05764.13 ORY29429.1 - 0.065 13.4 8.7 0.18 11.9 8.7 1.7 1 0 0 1 1 1 0 YL1 nuclear protein Nop53 PF07767.11 ORY29429.1 - 0.25 10.7 6.9 0.51 9.7 6.9 1.4 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Myc_N PF01056.18 ORY29429.1 - 0.47 10.3 8.0 4 7.2 4.4 2.3 2 0 0 2 2 2 0 Myc amino-terminal region SDA1 PF05285.12 ORY29429.1 - 0.59 9.5 22.4 2.2 7.6 17.3 2.3 2 0 0 2 2 2 0 SDA1 CDC45 PF02724.14 ORY29429.1 - 0.73 8.0 13.6 1.3 7.3 13.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid_p PF12226.8 ORY29429.1 - 0.85 8.7 13.4 1.7 7.7 13.4 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Vfa1 PF08432.10 ORY29429.1 - 1.4 9.3 4.7 1 9.6 2.4 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Sporozoite_P67 PF05642.11 ORY29429.1 - 1.8 6.5 4.9 3.2 5.7 4.9 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 ORY29429.1 - 2.1 6.3 21.0 0.099 10.7 15.1 1.6 2 0 0 2 2 2 0 DNA polymerase phi DUF2457 PF10446.9 ORY29429.1 - 4.7 6.2 29.5 1.6 7.8 24.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Protamine_P2 PF00841.19 ORY29429.1 - 8.1 7.0 7.8 0.22 12.0 0.4 2.2 2 0 0 2 2 1 0 Sperm histone P2 RXT2_N PF08595.11 ORY29429.1 - 9.5 6.2 9.6 29 4.6 9.6 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal RVT_1 PF00078.27 ORY29430.1 - 1.2e-06 28.2 0.0 3.2e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF640 PF04852.12 ORY29431.1 - 5.2e-09 36.3 0.0 9.1e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF640) ESCRT-II PF05871.12 ORY29432.1 - 1.7e-41 141.7 1.6 3.5e-41 140.7 1.0 1.7 1 1 1 2 2 2 1 ESCRT-II complex subunit Methyltransf_PK PF05891.12 ORY29433.1 - 3.1e-77 259.0 0.0 3.5e-77 258.8 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 ORY29433.1 - 7.1e-09 36.3 0.0 1.1e-08 35.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY29433.1 - 2.4e-07 31.3 0.0 3.9e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY29433.1 - 2.8e-06 28.0 0.0 4.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY29433.1 - 6e-06 26.2 0.0 2.2e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ORY29433.1 - 0.0051 16.1 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 ORY29433.1 - 0.0068 16.2 0.0 0.0091 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DNA_pol_phi PF04931.13 ORY29434.1 - 4e-182 607.2 9.7 5.7e-182 606.8 9.7 1.2 1 0 0 1 1 1 1 DNA polymerase phi SDA1 PF05285.12 ORY29434.1 - 5.6e-06 26.0 20.1 1.2e-05 24.9 20.1 1.6 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 ORY29434.1 - 0.00015 20.2 20.8 0.00032 19.1 20.8 1.6 1 0 0 1 1 1 1 Nop14-like family FANCI_S2 PF14676.6 ORY29434.1 - 0.0087 16.4 0.5 0.042 14.2 0.2 2.3 2 0 0 2 2 2 1 FANCI solenoid 2 DUF2115 PF09888.9 ORY29434.1 - 0.06 13.9 0.0 20 5.6 0.0 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) CDC45 PF02724.14 ORY29434.1 - 0.42 8.9 18.7 0.83 7.9 18.7 1.4 1 0 0 1 1 1 0 CDC45-like protein SH3_1 PF00018.28 ORY29435.1 - 1.4e-10 40.6 0.0 2.2e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY29435.1 - 5.7e-08 32.5 0.1 9.9e-08 31.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY29435.1 - 3.5e-07 29.8 0.0 6.8e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF2076 PF09849.9 ORY29435.1 - 0.58 10.2 5.9 0.81 9.7 5.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) PRCC PF10253.9 ORY29435.1 - 1.8 9.3 6.5 2.3 9.0 6.5 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF2070 PF09843.9 ORY29435.1 - 3.2 5.9 8.4 4 5.6 8.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TFIIA PF03153.13 ORY29435.1 - 3.9 7.4 5.6 4.7 7.1 5.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SH3_1 PF00018.28 ORY29436.1 - 2.8e-09 36.4 0.0 5.3e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY29436.1 - 2.7e-05 23.8 0.0 4.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ORY29436.1 - 0.00033 20.5 0.0 0.0009 19.1 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain CRIM PF16978.5 ORY29436.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), middle CRIM domain DUF4436 PF14494.6 ORY29437.1 - 1.1e-25 90.4 1.0 1.8e-25 89.7 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) Ribosomal_S12 PF17487.2 ORY29437.1 - 0.099 13.4 0.8 0.099 13.4 0.8 2.5 3 0 0 3 3 3 0 Ribosomal protein S12 HgmA PF04209.13 ORY29438.1 - 4e-205 681.4 0.0 4.5e-205 681.3 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Methyltransf_23 PF13489.6 ORY29439.1 - 1.2e-14 54.5 0.0 1.4e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY29439.1 - 1.9e-14 54.1 0.0 2.8e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY29439.1 - 2.2e-14 53.9 0.0 3.3e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY29439.1 - 3.1e-14 53.5 0.0 4.3e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY29439.1 - 2.3e-13 50.2 0.0 2.9e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY29439.1 - 0.00024 20.5 0.0 0.0003 20.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 ORY29439.1 - 0.00059 19.6 0.0 0.0011 18.7 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_9 PF08003.11 ORY29439.1 - 0.0012 17.9 0.0 0.0016 17.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.12 ORY29439.1 - 0.0018 17.9 0.0 0.0034 17.0 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 ORY29439.1 - 0.0026 17.7 0.0 0.0059 16.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 ORY29439.1 - 0.0032 16.8 0.0 0.0039 16.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 ORY29439.1 - 0.0056 16.2 0.0 0.0075 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 ORY29439.1 - 0.0097 15.3 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB CheR PF01739.18 ORY29439.1 - 0.045 13.2 0.0 0.08 12.4 0.0 1.4 1 1 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.17 ORY29439.1 - 0.18 11.2 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Lipase_GDSL PF00657.22 ORY29440.1 - 0.0082 16.1 0.0 0.4 10.6 0.0 2.2 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase BUD22 PF09073.10 ORY29441.1 - 2.4e-40 139.2 77.4 7.1e-18 65.2 38.1 6.0 1 1 4 5 5 5 5 BUD22 Mlf1IP PF10248.9 ORY29441.1 - 0.29 11.1 5.1 0.64 10.0 0.3 2.4 1 1 1 2 2 2 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Ribosomal_S2 PF00318.20 ORY29442.1 - 1.3e-22 80.1 0.8 4.6e-12 45.6 0.1 2.4 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 ORY29442.1 - 1e-05 26.8 6.9 2.2e-05 25.8 6.9 1.6 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus PGK PF00162.19 ORY29443.1 - 2.4e-152 507.3 1.4 2.7e-152 507.1 1.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase CBM_5_12_2 PF14600.6 ORY29444.1 - 0.00037 20.4 4.4 0.00037 20.4 4.4 1.7 2 0 0 2 2 2 1 Cellulose-binding domain CBM_5_12 PF02839.14 ORY29444.1 - 0.1 13.2 4.8 0.1 13.2 4.8 2.8 3 1 0 3 3 3 0 Carbohydrate binding domain AIM24 PF01987.17 ORY29445.1 - 0.019 14.7 0.0 0.37 10.5 0.0 2.0 1 1 1 2 2 2 0 Mitochondrial biogenesis AIM24 eIF-5a PF01287.20 ORY29446.1 - 1.3e-28 98.9 0.5 1.9e-28 98.3 0.5 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 ORY29446.1 - 0.039 14.0 0.1 0.11 12.5 0.1 1.7 2 0 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain Beta-lactamase PF00144.24 ORY29447.1 - 2.1e-35 122.6 0.2 4e-21 75.6 0.0 2.3 1 1 1 2 2 2 2 Beta-lactamase Glyco_hydro_19 PF00182.19 ORY29447.1 - 2.1e-10 40.9 2.6 4e-10 40.0 1.2 2.1 1 1 1 2 2 2 1 Chitinase class I DUF3471 PF11954.8 ORY29447.1 - 2.3e-05 24.8 0.1 8.5e-05 23.0 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3471) DUF3671 PF12420.8 ORY29447.1 - 0.14 12.3 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function Mucin PF01456.17 ORY29447.1 - 0.51 10.3 37.9 1 9.4 37.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.11 ORY29447.1 - 7.9 6.9 18.2 17 5.9 18.2 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Beta-lactamase PF00144.24 ORY29448.1 - 7.2e-49 166.8 0.0 8.8e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Aph-1 PF06105.12 ORY29449.1 - 1.5e-43 148.8 17.2 2e-43 148.5 17.2 1.0 1 0 0 1 1 1 1 Aph-1 protein WD40 PF00400.32 ORY29450.1 - 1.7e-22 79.3 18.6 3.9e-05 24.3 0.7 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY29450.1 - 1.3e-08 35.0 7.8 0.0074 16.6 0.6 4.0 2 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY29450.1 - 0.00082 18.4 0.4 0.22 10.4 0.0 3.6 2 2 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 ORY29450.1 - 0.006 14.6 2.2 0.072 11.1 0.0 2.0 2 0 0 2 2 2 2 IKI3 family zf-C2H2_4 PF13894.6 ORY29451.1 - 0.003 18.3 2.0 2.2 9.3 1.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 ORY29451.1 - 0.0081 16.8 1.8 2.1 9.0 0.1 2.3 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 ORY29451.1 - 0.066 13.2 3.0 0.23 11.5 0.3 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 ORY29452.1 - 1.3e-06 28.7 18.4 0.022 15.5 1.9 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY29452.1 - 0.016 15.6 0.2 0.016 15.6 0.2 4.8 5 1 0 5 5 5 0 Zinc-finger double domain zf-C2H2 PF00096.26 ORY29452.1 - 0.018 15.5 21.3 0.11 13.0 2.1 5.0 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-MYST PF17772.1 ORY29452.1 - 0.089 12.4 0.9 0.18 11.4 0.3 1.8 1 1 1 2 2 2 0 MYST family zinc finger domain zf-C2H2_6 PF13912.6 ORY29452.1 - 0.3 11.1 11.7 2.4 8.2 0.3 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 ORY29452.1 - 0.47 10.4 8.6 1.2 9.1 0.5 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-met PF12874.7 ORY29452.1 - 0.66 10.4 7.7 2 9.0 0.4 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Mito_fiss_reg PF05308.11 ORY29452.1 - 0.82 9.7 3.7 1.2 9.1 3.7 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator zf-C2H2_jaz PF12171.8 ORY29452.1 - 2.4 8.5 12.4 0.083 13.2 1.9 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding PRIMA1 PF16101.5 ORY29452.1 - 3.6 7.6 11.9 7 6.7 11.9 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 FAM76 PF16046.5 ORY29453.1 - 0.0078 15.6 3.2 0.0088 15.4 3.2 1.2 1 0 0 1 1 1 1 FAM76 protein Tsc35 PF15079.6 ORY29453.1 - 0.02 14.5 0.1 0.025 14.2 0.1 1.2 1 0 0 1 1 1 0 Testis-specific protein 35 Fib_alpha PF08702.10 ORY29453.1 - 0.025 14.7 8.7 0.039 14.1 8.7 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Glu_syn_central PF04898.14 ORY29453.1 - 0.029 13.8 1.3 0.035 13.6 1.3 1.1 1 0 0 1 1 1 0 Glutamate synthase central domain Atg14 PF10186.9 ORY29453.1 - 0.037 13.1 8.2 0.053 12.6 8.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MetOD2 PF18548.1 ORY29453.1 - 0.039 14.0 5.7 0.16 12.1 0.8 2.2 2 0 0 2 2 2 0 Metanogen output domain 2 Herpes_BBRF1 PF04793.12 ORY29453.1 - 0.082 11.9 1.3 0.51 9.3 0.1 1.9 1 1 1 2 2 2 0 BRRF1-like protein FUSC PF04632.12 ORY29453.1 - 0.2 10.2 2.5 0.23 10.0 2.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Apolipoprotein PF01442.18 ORY29453.1 - 0.31 10.9 12.9 0.7 9.7 12.9 1.6 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain AI-2E_transport PF01594.16 ORY29453.1 - 0.31 10.1 3.0 0.31 10.2 2.0 1.5 1 1 1 2 2 2 0 AI-2E family transporter BST2 PF16716.5 ORY29453.1 - 0.31 11.6 13.5 0.3 11.7 5.5 2.3 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 FapA PF03961.13 ORY29453.1 - 0.35 9.4 4.1 0.44 9.1 4.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Swi5 PF07061.11 ORY29453.1 - 0.53 10.4 6.3 1.3 9.1 6.3 1.8 1 1 0 1 1 1 0 Swi5 TMPIT PF07851.13 ORY29453.1 - 0.63 9.2 5.2 0.8 8.9 5.2 1.2 1 0 0 1 1 1 0 TMPIT-like protein YtxH PF12732.7 ORY29453.1 - 0.66 10.6 2.9 26 5.4 3.6 2.4 2 1 0 2 2 1 0 YtxH-like protein ApoO PF09769.9 ORY29453.1 - 0.71 9.8 3.6 0.69 9.9 0.9 2.0 1 1 1 2 2 2 0 Apolipoprotein O TMF_DNA_bd PF12329.8 ORY29453.1 - 0.81 9.7 13.8 40 4.3 13.7 2.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF948 PF06103.11 ORY29453.1 - 3.1 8.1 6.2 43 4.5 5.1 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Flagellin_N PF00669.20 ORY29453.1 - 5.9 7.0 12.5 2.5 8.2 6.5 2.3 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region Ribosomal_L18A PF01775.17 ORY29454.1 - 4.6e-55 184.9 1.1 5.9e-55 184.6 1.1 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A zf-C2H2_aberr PF17017.5 ORY29455.1 - 0.0018 18.5 2.7 0.017 15.3 0.1 2.1 1 1 1 2 2 2 1 Aberrant zinc-finger zf-RAG1 PF10426.9 ORY29455.1 - 0.0065 16.6 2.9 0.025 14.7 2.9 2.1 1 1 0 1 1 1 1 Recombination-activating protein 1 zinc-finger domain DUF2614 PF11023.8 ORY29455.1 - 0.14 12.3 0.2 0.14 12.3 0.2 1.9 2 1 1 3 3 3 0 Zinc-ribbon containing domain zf-C2H2_4 PF13894.6 ORY29455.1 - 0.79 10.7 11.7 19 6.5 0.9 4.2 3 2 0 3 3 3 0 C2H2-type zinc finger IBR PF01485.21 ORY29455.1 - 2.1 8.7 14.8 9 6.6 1.5 3.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Transpos_assoc PF13963.6 ORY29455.1 - 3.5 8.0 10.5 2.3 8.6 0.2 3.3 2 1 0 3 3 3 0 Transposase-associated domain zf-C2H2 PF00096.26 ORY29457.1 - 0.031 14.7 0.2 0.031 14.7 0.2 4.9 5 1 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY29457.1 - 0.032 15.0 22.6 1.6 9.8 2.3 4.5 4 1 0 4 4 4 0 C2H2-type zinc finger Rad50_zn_hook PF04423.14 ORY29457.1 - 0.24 11.3 2.9 0.18 11.7 0.8 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-H2C2_2 PF13465.6 ORY29457.1 - 0.35 11.4 0.0 0.35 11.4 0.0 3.9 5 0 0 5 5 5 0 Zinc-finger double domain zinc_ribbon_4 PF13717.6 ORY29457.1 - 1.3 9.0 13.6 4.8 7.2 1.0 4.1 4 0 0 4 4 4 0 zinc-ribbon domain Endonuclease_7 PF02945.15 ORY29457.1 - 2.8 7.9 10.7 3 7.8 3.1 2.3 1 1 1 2 2 2 0 Recombination endonuclease VII zf_UBZ PF18439.1 ORY29457.1 - 3.8 7.2 8.1 17 5.1 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 ORY29457.1 - 6.1 7.2 13.2 23 5.4 0.9 3.2 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RAG1 PF10426.9 ORY29458.1 - 0.0084 16.2 0.5 0.035 14.2 0.5 2.1 1 0 0 1 1 1 1 Recombination-activating protein 1 zinc-finger domain Rad50_zn_hook PF04423.14 ORY29458.1 - 0.041 13.7 0.3 0.11 12.4 0.3 1.7 1 0 0 1 1 1 0 Rad50 zinc hook motif Zn-ribbon_8 PF09723.10 ORY29458.1 - 0.071 13.2 0.8 0.071 13.2 0.8 3.5 4 0 0 4 4 4 0 Zinc ribbon domain zf-C2H2_aberr PF17017.5 ORY29458.1 - 1.4 9.1 11.1 4.6 7.4 1.3 2.6 1 1 1 2 2 2 0 Aberrant zinc-finger zf-H2C2_2 PF13465.6 ORY29458.1 - 1.5 9.4 21.1 0.29 11.6 5.9 4.0 4 0 0 4 4 4 0 Zinc-finger double domain zinc_ribbon_4 PF13717.6 ORY29458.1 - 2 8.4 13.5 5.2 7.1 0.2 3.3 3 1 0 3 3 3 0 zinc-ribbon domain zf-C2H2 PF00096.26 ORY29458.1 - 5.7 7.6 25.5 0.15 12.5 1.5 5.3 4 2 0 4 4 4 0 Zinc finger, C2H2 type YdjO PF14169.6 ORY29459.1 - 0.002 17.8 2.1 0.0059 16.3 2.1 1.9 1 1 0 1 1 1 1 Cold-inducible protein YdjO zf-H2C2_2 PF13465.6 ORY29459.1 - 0.041 14.3 0.9 0.041 14.3 0.9 3.5 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY29459.1 - 0.059 13.7 0.2 0.059 13.7 0.2 2.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY29459.1 - 0.094 13.1 2.8 0.66 10.5 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 ORY29459.1 - 0.15 12.6 0.2 0.15 12.6 0.2 4.7 4 2 0 4 4 4 0 Zinc finger, C2H2 type Glucosamine_iso PF01182.20 ORY29460.1 - 9.3e-69 231.7 0.0 1.3e-68 231.3 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF1424 PF07232.11 ORY29460.1 - 0.074 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative rep protein (DUF1424) FAT PF02259.23 ORY29461.1 - 7.7e-42 143.7 0.6 5.8e-38 131.0 0.9 4.2 2 1 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 ORY29461.1 - 4.6e-33 115.1 0.4 1.4e-32 113.5 0.4 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 ORY29461.1 - 0.0089 15.8 0.3 0.1 12.5 0.0 2.7 2 0 0 2 2 2 1 FATC domain Met_synt_B12 PF02965.17 ORY29464.1 - 7.5e-58 196.2 0.0 1.1e-57 195.6 0.0 1.2 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain B12-binding PF02310.19 ORY29464.1 - 2.7e-20 72.6 0.6 5.3e-20 71.7 0.6 1.5 1 0 0 1 1 1 1 B12 binding domain Beta-lactamase PF00144.24 ORY29465.1 - 5.1e-29 101.6 0.1 3.6e-24 85.6 0.1 2.8 1 1 1 2 2 2 2 Beta-lactamase DUF3471 PF11954.8 ORY29465.1 - 0.0048 17.4 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) SafA PF17073.5 ORY29467.1 - 0.065 13.2 0.7 0.14 12.1 0.7 1.5 1 0 0 1 1 1 0 Two-component-system connector protein DnaJ PF00226.31 ORY29468.1 - 1.2e-07 31.7 0.3 3.1e-07 30.4 0.1 1.9 2 0 0 2 2 2 1 DnaJ domain AIM24 PF01987.17 ORY29469.1 - 1.3e-35 123.0 0.0 1.7e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Mcp5_PH PF12814.7 ORY29469.1 - 0.044 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology WW PF00397.26 ORY29469.1 - 0.18 11.9 5.2 0.32 11.1 0.1 3.1 4 0 0 4 4 4 0 WW domain Beta-lactamase PF00144.24 ORY29470.1 - 4.1e-53 180.8 0.0 5.7e-53 180.3 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 ORY29470.1 - 9.6e-06 26.0 0.0 2.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Beta-lactamase2 PF13354.6 ORY29470.1 - 0.16 11.6 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase enzyme family AIM24 PF01987.17 ORY29471.1 - 3.4e-38 131.5 0.1 3.8e-38 131.3 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 LRR_8 PF13855.6 ORY29472.1 - 2.6e-21 75.1 26.2 1.7e-08 34.1 6.8 3.4 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY29472.1 - 5.5e-14 52.1 29.1 1.2e-05 25.6 0.1 4.8 2 2 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY29472.1 - 4.3e-11 41.7 29.8 0.0077 16.6 0.5 7.4 7 1 0 7 7 7 6 Leucine Rich Repeat LRR_6 PF13516.6 ORY29472.1 - 0.00017 21.4 22.7 0.81 9.9 0.2 6.5 6 0 0 6 6 6 2 Leucine Rich repeat F-box PF00646.33 ORY29472.1 - 0.0055 16.5 0.9 0.013 15.3 0.1 2.1 2 0 0 2 2 2 1 F-box domain Pou PF00157.17 ORY29472.1 - 0.019 14.9 0.0 1.9 8.5 0.0 2.6 2 0 0 2 2 2 0 Pou domain - N-terminal to homeobox domain Acetyltransf_1 PF00583.25 ORY29473.1 - 1.1e-07 32.0 0.0 1.7e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY29473.1 - 1.9e-07 31.4 0.0 2.7e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY29473.1 - 0.00036 20.5 0.0 0.00064 19.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.6 ORY29473.1 - 0.19 11.1 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase 2 AP_endonuc_2 PF01261.24 ORY29477.1 - 0.00021 20.8 0.0 0.0003 20.3 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Lipase_GDSL PF00657.22 ORY29478.1 - 7.1e-14 52.3 4.9 2.1e-06 27.9 1.2 2.4 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase Ephrin_rec_like PF07699.13 ORY29479.1 - 0.0009 19.0 4.5 0.0009 19.0 4.5 9.4 4 3 4 9 9 9 3 Putative ephrin-receptor like NCD3G PF07562.14 ORY29479.1 - 1.6 8.7 46.7 0.022 14.8 4.2 7.3 6 1 1 7 7 7 0 Nine Cysteines Domain of family 3 GPCR TANGO2 PF05742.12 ORY29480.1 - 3.9e-23 82.8 0.0 9.9e-23 81.5 0.0 1.5 2 0 0 2 2 2 1 Transport and Golgi organisation 2 Rep_fac-A_C PF08646.10 ORY29481.1 - 2.9 7.6 6.3 0.63 9.8 2.6 1.8 2 0 0 2 2 2 0 Replication factor-A C terminal domain zinc_ribbon_4 PF13717.6 ORY29481.1 - 4.3 7.3 9.6 5 7.1 0.4 2.8 2 1 0 2 2 2 0 zinc-ribbon domain IBR PF01485.21 ORY29481.1 - 5.3 7.4 15.9 0.93 9.8 5.1 3.0 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain IBR PF01485.21 ORY29483.1 - 0.68 10.2 20.8 0.53 10.6 7.0 3.2 1 1 1 3 3 3 0 IBR domain, a half RING-finger domain zf-C2H2_4 PF13894.6 ORY29483.1 - 4.2 8.5 17.8 11 7.2 0.6 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger PI3_PI4_kinase PF00454.27 ORY29484.1 - 2.6e-39 135.6 0.0 3.8e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase CM_2 PF01817.21 ORY29485.1 - 0.0063 16.8 1.3 0.49 10.8 0.0 3.3 3 1 0 3 3 3 1 Chorismate mutase type II Ribosomal_L28e PF01778.17 ORY29486.1 - 1.2e-26 93.7 0.1 1.5e-26 93.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF5612 PF18462.1 ORY29486.1 - 0.025 14.4 0.1 0.03 14.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5612) MIF4G_like PF09088.11 ORY29487.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 MIF4G like NAD_binding_3 PF03447.16 ORY29488.1 - 0.12 13.0 0.0 0.31 11.7 0.0 1.6 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Ribosomal_L34e PF01199.18 ORY29489.1 - 7.9e-44 147.9 3.8 7.9e-44 147.9 3.8 1.6 2 0 0 2 2 2 1 Ribosomal protein L34e UPF0029 PF01205.19 ORY29489.1 - 0.012 16.0 1.7 0.035 14.4 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized protein family UPF0029 FhuF_C PF11575.8 ORY29489.1 - 0.057 13.4 1.5 3 7.9 0.4 2.5 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain zinc_ribbon_12 PF11331.8 ORY29489.1 - 0.16 11.8 0.7 6.5 6.7 0.1 2.5 2 0 0 2 2 2 0 Probable zinc-ribbon domain Cystatin PF00031.21 ORY29490.1 - 0.082 13.2 0.3 0.17 12.2 0.3 1.7 1 1 0 1 1 1 0 Cystatin domain ABC2_membrane PF01061.24 ORY29491.1 - 6e-30 104.2 29.1 8.4e-30 103.8 29.1 1.1 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 ORY29491.1 - 2.7e-24 86.2 0.0 4.1e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY29491.1 - 4.2e-08 33.4 0.0 0.007 16.2 0.0 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ORY29491.1 - 0.00016 21.9 0.0 0.00046 20.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORY29491.1 - 0.00018 21.2 0.2 0.00049 19.8 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ORY29491.1 - 0.00062 19.4 0.0 0.044 13.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 ORY29491.1 - 0.0021 18.0 0.1 0.0042 17.0 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 ORY29491.1 - 0.0045 16.5 0.0 2 7.8 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY29491.1 - 0.0058 17.0 0.0 0.0088 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 ORY29491.1 - 0.032 14.1 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain NACHT PF05729.12 ORY29491.1 - 0.13 12.2 0.5 0.24 11.3 0.1 1.6 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.23 ORY29491.1 - 0.14 12.2 0.1 0.26 11.3 0.1 1.6 1 1 0 1 1 1 0 Dynamin family AAA_18 PF13238.6 ORY29491.1 - 0.14 12.7 0.1 0.24 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORY29491.1 - 0.14 12.3 0.1 0.32 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ORY29491.1 - 0.17 11.9 0.1 8 6.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.6 ORY29491.1 - 0.27 9.8 0.3 1.1 7.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ORY29492.1 - 3.6e-21 76.1 0.0 5.7e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 ORY29492.1 - 8.9e-08 31.8 29.6 2.9e-06 26.8 21.6 2.2 1 1 1 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.6 ORY29492.1 - 2.4e-06 27.6 0.0 0.0048 16.7 0.0 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY29492.1 - 0.005 16.5 1.8 0.053 13.3 0.2 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 ORY29492.1 - 0.014 14.8 0.0 0.12 11.8 0.0 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ORY29492.1 - 0.11 12.4 0.1 0.4 10.6 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 ORY29492.1 - 0.22 11.7 0.1 1 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF872 PF05915.12 ORY29492.1 - 1.6 9.0 5.1 0.23 11.6 0.2 2.1 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) ABC2_membrane PF01061.24 ORY29493.1 - 9e-36 123.3 27.0 1.4e-35 122.7 27.0 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 ORY29493.1 - 7.6e-25 88.0 0.0 1.4e-24 87.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY29493.1 - 1.9e-05 24.7 0.0 0.0067 16.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY29493.1 - 4.1e-05 23.1 0.0 0.00013 21.5 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.7 ORY29493.1 - 7.7e-05 22.0 12.5 7.7e-05 22.0 12.5 1.9 2 0 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 ORY29493.1 - 0.0019 18.1 0.2 0.012 15.5 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 ORY29493.1 - 0.002 17.8 0.1 0.0061 16.3 0.1 1.7 1 1 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ORY29493.1 - 0.0028 17.3 0.1 0.41 10.2 0.1 3.2 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.6 ORY29493.1 - 0.088 13.1 0.1 0.39 11.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORY29493.1 - 0.099 12.8 0.1 0.3 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 ORY29493.1 - 0.12 12.3 0.4 0.32 10.9 0.0 1.9 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_16 PF13191.6 ORY29493.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_13 PF13166.6 ORY29493.1 - 0.17 10.5 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Myb_DNA-bind_4 PF13837.6 ORY29612.1 - 0.00017 21.9 0.3 0.00039 20.8 0.3 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain IDO PF01231.18 ORY29612.1 - 0.0031 16.3 0.0 0.0081 15.0 0.0 1.6 1 1 1 2 2 2 1 Indoleamine 2,3-dioxygenase MADF_DNA_bdg PF10545.9 ORY29612.1 - 0.0098 16.2 0.1 0.029 14.7 0.1 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase transcription factor Myb/SANT-like UBN_AB PF14075.6 ORY29612.1 - 0.078 12.7 0.3 0.078 12.7 0.3 1.8 2 0 0 2 2 2 0 Ubinuclein conserved middle domain PaRep2b PF07775.11 ORY29612.1 - 0.11 11.0 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 PaRep2b protein DDE_Tnp_4 PF13359.6 ORY29613.1 - 4.4e-07 29.7 0.0 6.7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3652 PF12372.8 ORY29616.1 - 0.14 12.0 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Huntingtin protein region HTH_45 PF14947.6 ORY29720.1 - 0.00078 19.4 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 2 Winged helix-turn-helix RVT_1 PF00078.27 ORY29722.1 - 1.2e-06 28.3 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) ANF_receptor PF01094.28 ORY29724.1 - 4.4e-19 68.8 0.0 6.8e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 ORY29724.1 - 6e-18 65.4 23.3 1.2e-17 64.5 23.3 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 ORY29724.1 - 1.1e-06 28.6 1.9 2.6e-06 27.3 1.9 1.7 1 0 0 1 1 1 1 Periplasmic binding protein DUF2417 PF10329.9 ORY29724.1 - 0.0061 16.0 4.8 0.0061 16.0 4.8 2.4 1 1 1 2 2 2 1 Region of unknown function (DUF2417) Ank_2 PF12796.7 ORY29725.1 - 0.00022 21.7 2.3 1.8 9.2 0.0 4.6 4 2 2 6 6 6 3 Ankyrin repeats (3 copies) bacHORMA_2 PF18173.1 ORY29725.1 - 0.15 11.9 0.5 0.36 10.7 0.1 1.8 2 0 0 2 2 2 0 Bacterial HORMA domain 2 DUF1279 PF06916.13 ORY29726.1 - 8.5e-08 32.6 0.0 3.8e-07 30.6 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Baculo_PEP_C PF04513.12 ORY29726.1 - 0.0054 16.8 0.1 0.0091 16.0 0.1 1.3 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.18 ORY29726.1 - 0.031 14.1 0.7 0.059 13.2 0.7 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain Cytochrom_B562 PF07361.11 ORY29726.1 - 0.39 11.4 0.1 0.39 11.4 0.1 1.6 2 0 0 2 2 2 0 Cytochrome b562 DUF1279 PF06916.13 ORY29727.1 - 7.9e-06 26.3 0.0 1.2e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Glyco_transf_8 PF01501.20 ORY29728.1 - 3e-11 43.4 0.0 4.2e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 ORY29728.1 - 0.0039 16.6 0.0 0.033 13.5 0.0 2.0 2 0 0 2 2 2 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 ORY29728.1 - 0.0088 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Laminin_G_3 PF13385.6 ORY29729.1 - 8.4e-08 32.5 0.2 0.00024 21.3 0.1 2.4 2 1 0 2 2 2 2 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 ORY29729.1 - 0.037 14.6 0.0 7.7 7.1 0.0 2.6 2 0 0 2 2 2 0 Laminin G domain Trp_syntA PF00290.20 ORY29729.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain Ammonium_transp PF00909.21 ORY29730.1 - 9.5e-113 376.9 25.1 1.1e-112 376.7 25.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Methyltransf_25 PF13649.6 ORY29731.1 - 8e-06 26.5 0.0 1.6e-05 25.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY29731.1 - 2.6e-05 24.0 0.2 3.5e-05 23.7 0.2 1.3 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORY29731.1 - 0.00027 20.3 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 ORY29731.1 - 0.0012 18.3 0.2 0.0018 17.8 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 ORY29731.1 - 0.0054 16.6 0.1 0.0086 15.9 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORY29731.1 - 0.0065 16.2 0.0 0.0087 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 ORY29731.1 - 0.016 15.8 0.1 0.039 14.6 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 ORY29731.1 - 0.028 14.0 0.1 0.039 13.5 0.1 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.17 ORY29731.1 - 0.038 13.5 0.0 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase DOT1 PF08123.13 ORY29731.1 - 0.071 12.6 0.2 0.098 12.2 0.2 1.4 1 1 0 1 1 1 0 Histone methylation protein DOT1 TMEM131_like PF12371.8 ORY29731.1 - 0.16 12.2 0.0 0.25 11.6 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 131-like TehB PF03848.14 ORY29731.1 - 0.17 11.3 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB KilA-N PF04383.13 ORY29732.1 - 2.4e-08 33.8 0.1 3e-06 27.0 0.1 2.3 1 1 0 1 1 1 1 KilA-N domain Casein_kappa PF00997.18 ORY29732.1 - 1.6 8.8 5.9 0.88 9.7 3.6 1.7 2 0 0 2 2 2 0 Kappa casein AAA_9 PF12781.7 ORY29733.1 - 0.13 11.3 0.0 0.39 9.8 0.0 1.7 2 0 0 2 2 2 0 ATP-binding dynein motor region FA_desaturase PF00487.24 ORY29734.1 - 4.4e-14 52.9 19.7 4.4e-14 52.9 19.7 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 ORY29734.1 - 2.4e-10 40.4 0.0 4.6e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4191 PF13829.6 ORY29734.1 - 0.14 11.4 2.2 0.14 11.5 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) AMP-binding PF00501.28 ORY29735.1 - 5.7e-98 328.3 0.0 7.6e-98 327.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY29735.1 - 0.015 16.3 0.0 0.043 14.8 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain CoA_binding_2 PF13380.6 ORY29735.1 - 0.053 14.0 0.0 1.8 9.1 0.0 2.4 2 0 0 2 2 2 0 CoA binding domain AMP-binding PF00501.28 ORY29736.1 - 4.1e-81 272.7 0.1 5.7e-81 272.3 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF190 PF02641.15 ORY29736.1 - 0.1 12.9 0.0 0.64 10.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized ACR, COG1993 AMP-binding_C PF13193.6 ORY29736.1 - 0.11 13.6 0.0 0.41 11.7 0.0 2.1 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 ORY29737.1 - 7.6e-94 314.7 0.1 1.1e-93 314.1 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY29737.1 - 0.072 14.1 0.0 0.2 12.6 0.0 1.9 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain bacHORMA_2 PF18173.1 ORY29737.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial HORMA domain 2 AMP-binding PF00501.28 ORY29738.1 - 2.6e-96 322.8 0.6 3.3e-96 322.5 0.6 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY29738.1 - 0.069 14.1 0.0 0.22 12.5 0.0 2.0 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 ORY29739.1 - 2.6e-97 326.1 0.0 6.2e-97 324.9 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY29739.1 - 0.00045 21.2 0.1 0.00099 20.0 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SH3_1 PF00018.28 ORY29739.1 - 0.073 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 SH3 domain FtsX PF02687.21 ORY29739.1 - 0.58 10.7 2.0 8.4 6.9 0.0 2.4 2 0 0 2 2 2 0 FtsX-like permease family AMP-binding PF00501.28 ORY29740.1 - 1.4e-78 264.4 0.1 1.7e-78 264.1 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme RCC1 PF00415.18 ORY29864.1 - 2.1e-31 108.3 6.4 1.8e-07 31.7 0.0 4.6 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY29864.1 - 7e-12 44.8 9.4 3.5e-06 26.7 0.2 4.3 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat DNA_methylase PF00145.17 ORY29865.1 - 3.5e-49 168.0 0.0 2.3e-38 132.4 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase HSP90 PF00183.18 ORY29865.1 - 0.15 10.9 1.6 0.22 10.4 1.6 1.1 1 0 0 1 1 1 0 Hsp90 protein GA-like PF17573.2 ORY29867.1 - 0.14 12.1 0.6 1.2 9.2 0.1 2.2 2 0 0 2 2 2 0 GA-like domain DDE_3 PF13358.6 ORY29872.1 - 3.5e-07 30.1 0.6 4.7e-07 29.7 0.6 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RNase_H PF00075.24 ORY29873.1 - 0.0002 21.6 0.0 0.00027 21.1 0.0 1.3 1 0 0 1 1 1 1 RNase H Peptidase_M14 PF00246.24 ORY29874.1 - 2.8e-29 102.8 0.6 3.1e-29 102.7 0.6 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase DDE_Tnp_4 PF13359.6 ORY29875.1 - 1.6e-17 63.6 0.0 1.1e-10 41.4 0.0 2.2 1 1 1 2 2 2 2 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 ORY29875.1 - 0.011 15.3 0.0 0.61 9.7 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain DNA_methylase PF00145.17 ORY29878.1 - 7.7e-60 203.0 0.0 9e-45 153.5 0.0 2.1 1 1 0 2 2 2 2 C-5 cytosine-specific DNA methylase UDPGT PF00201.18 ORY29879.1 - 9.5e-23 80.7 0.0 1.4e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ADH_zinc_N_2 PF13602.6 ORY29879.1 - 9.2e-10 39.7 0.0 2.3e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY29879.1 - 9.8e-09 35.1 1.0 9.8e-09 35.1 1.0 2.1 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY29879.1 - 4.3e-07 30.0 1.5 8.3e-07 29.0 0.2 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glyco_tran_28_C PF04101.16 ORY29879.1 - 4.6e-07 30.0 0.0 7.9e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.6 ORY29879.1 - 0.016 14.5 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 ELFV_dehydrog PF00208.21 ORY29879.1 - 0.97 9.1 7.4 0.038 13.7 1.2 1.7 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase rOmpB PF12334.8 ORY29880.1 - 0.077 12.5 0.2 0.1 12.0 0.2 1.2 1 0 0 1 1 1 0 Rickettsia outer membrane protein B Mannosyl_trans3 PF11051.8 ORY29881.1 - 4.2e-19 69.0 0.8 4e-11 42.8 0.3 2.0 1 1 1 2 2 2 2 Mannosyltransferase putative Glyco_transf_8 PF01501.20 ORY29881.1 - 0.048 13.2 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 8 Zwilch PF09817.9 ORY29884.1 - 1.8e-08 33.3 0.0 2e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 RZZ complex, subunit zwilch DMA PF03474.14 ORY29884.1 - 0.15 11.6 1.4 0.48 10.1 0.1 2.5 3 0 0 3 3 3 0 DMRTA motif UDPGP PF01704.18 ORY29885.1 - 9.5e-46 156.3 0.0 2.4e-43 148.3 0.0 2.0 1 1 1 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 ORY29885.1 - 0.012 16.0 0.0 0.034 14.5 0.0 1.8 2 0 0 2 2 2 0 MobA-like NTP transferase domain Pheromone PF08015.11 ORY29885.1 - 0.17 12.9 0.8 1.5 10.0 0.0 2.5 2 0 0 2 2 2 0 Fungal mating-type pheromone UQ_con PF00179.26 ORY29886.1 - 3.8e-30 104.4 0.0 4.2e-30 104.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ADK PF00406.22 ORY29887.1 - 8.9e-38 129.8 0.0 1.2e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.14 ORY29887.1 - 2.8e-13 49.6 0.0 4.8e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 ORY29887.1 - 5.9e-12 46.2 0.0 1.3e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY29887.1 - 0.0064 17.0 0.0 0.01 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zn_clus PF00172.18 ORY29889.1 - 3.2e-09 36.8 20.7 0.00025 21.1 7.9 2.8 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY29889.1 - 0.026 13.6 4.0 0.028 13.4 1.1 2.4 1 1 1 2 2 2 0 Fungal specific transcription factor domain Mannosyl_trans3 PF11051.8 ORY29890.1 - 6.7e-30 104.4 0.0 3.4e-20 72.5 0.0 2.2 1 1 0 2 2 2 2 Mannosyltransferase putative Spermine_synth PF01564.17 ORY29891.1 - 2.4e-65 219.5 0.0 8.1e-65 217.8 0.0 1.7 2 0 0 2 2 2 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 ORY29891.1 - 4.3e-16 58.5 0.5 7e-16 57.9 0.5 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 ORY29891.1 - 0.00016 22.3 0.0 0.00027 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY29891.1 - 0.027 15.2 0.0 0.058 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF43 PF01861.16 ORY29891.1 - 0.17 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Branched-chain polyamine synthase A C-terminal domain DUF4050 PF13259.6 ORY29892.1 - 2.2e-12 47.7 0.6 4.5e-08 33.6 0.0 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF4050) Pkinase PF00069.25 ORY29893.1 - 1.8e-62 211.1 0.0 2.3e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY29893.1 - 5.6e-21 75.0 0.0 7.4e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY29893.1 - 4.9e-05 22.8 0.0 0.00013 21.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORY29893.1 - 0.0069 16.3 0.0 0.017 15.0 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY29893.1 - 0.056 13.0 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase FTA2 PF13095.6 ORY29893.1 - 0.068 12.8 0.0 0.18 11.4 0.0 1.4 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 ORY29893.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RhoGAP PF00620.27 ORY29894.1 - 4e-09 36.5 0.1 1.4e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 ORY29894.1 - 4.1e-07 30.2 3.7 7.1e-07 29.4 0.6 2.9 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.21 ORY29894.1 - 0.00033 20.6 0.0 0.00087 19.3 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Ribosomal_S3Ae PF01015.18 ORY29895.1 - 6.7e-91 303.3 3.8 7.9e-91 303.1 3.8 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 ORY29895.1 - 0.003 18.0 0.5 4.4 7.9 0.0 2.7 3 0 0 3 3 3 2 Translation initiation factor SUI1 CENP-R PF06729.12 ORY29895.1 - 0.05 13.5 0.6 4.4 7.2 0.0 2.2 1 1 1 2 2 2 0 Kinetochore component, CENP-R Abhydro_lipase PF04083.16 ORY29895.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Exo_endo_phos PF03372.23 ORY29897.1 - 1.8e-05 24.4 0.0 2.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family AraC_binding_2 PF14525.6 ORY29897.1 - 0.041 13.6 0.2 0.37 10.4 0.0 2.0 2 0 0 2 2 2 0 AraC-binding-like domain Pkinase PF00069.25 ORY29898.1 - 9.9e-75 251.3 0.0 1.2e-74 251.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY29898.1 - 1.1e-33 116.7 0.0 1.3e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY29898.1 - 6.3e-05 22.4 0.1 8.9e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY29898.1 - 0.00031 19.7 0.0 0.00059 18.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase WD40 PF00400.32 ORY29899.1 - 4.3e-39 131.8 16.1 6.6e-07 29.9 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY29899.1 - 4.6e-17 62.1 0.0 0.00036 20.8 0.0 5.1 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY29899.1 - 7.8e-05 22.6 0.0 0.1 12.5 0.0 2.9 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY29899.1 - 0.00023 20.6 0.0 0.00094 18.6 0.0 2.3 1 1 0 1 1 1 1 WD40-like domain Nup160 PF11715.8 ORY29899.1 - 0.04 12.6 0.6 2 7.0 0.0 2.2 1 1 0 2 2 2 0 Nucleoporin Nup120/160 GARS_A PF01071.19 ORY29900.1 - 1.6e-79 266.2 0.0 3.2e-79 265.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 ORY29900.1 - 1.7e-30 106.2 0.1 7.1e-30 104.2 0.0 2.0 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 ORY29900.1 - 3.5e-29 101.4 0.8 5e-28 97.7 0.1 3.1 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 ORY29900.1 - 1.1e-28 99.3 0.1 2.7e-28 98.0 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 ORY29900.1 - 6.8e-14 52.3 2.0 2.6e-13 50.4 2.0 2.2 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Lactamase_B_2 PF12706.7 ORY29900.1 - 0.052 13.1 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Glyco_hydro_26 PF02156.15 ORY29901.1 - 2.8e-06 27.0 6.7 0.0025 17.3 0.1 2.8 3 0 0 3 3 3 2 Glycosyl hydrolase family 26 Chromate_transp PF02417.15 ORY29904.1 - 4.5e-37 127.6 38.1 5.1e-27 94.9 16.5 2.5 2 1 0 2 2 2 2 Chromate transporter Zn_clus PF00172.18 ORY29905.1 - 2.1e-05 24.6 11.8 3.4e-05 23.9 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.22 ORY29906.1 - 8.3e-19 67.2 0.0 4.2e-11 42.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.11 ORY29906.1 - 0.0011 18.8 0.0 0.092 12.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1866) MG2 PF01835.19 ORY29907.1 - 0.0095 16.4 0.1 0.029 14.8 0.1 2.0 1 1 0 1 1 1 1 MG2 domain Plavaka PF18759.1 ORY29910.1 - 2.6e-24 86.1 0.0 4.6e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Plavaka transposase zf-C2H2_jaz PF12171.8 ORY29910.1 - 1.8e-05 24.9 0.6 4.4e-05 23.6 0.6 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY29910.1 - 0.0025 18.1 0.4 0.0069 16.7 0.4 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 ORY29910.1 - 0.016 15.5 1.2 0.038 14.3 0.1 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 ORY29910.1 - 0.018 15.9 0.1 0.094 13.6 0.1 2.3 1 0 0 1 1 1 0 C2H2-type zinc finger Lactamase_B_2 PF12706.7 ORY29912.1 - 1.2e-32 113.1 0.0 2.2e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORY29912.1 - 4e-12 46.3 0.0 1.4e-11 44.5 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY29912.1 - 0.0039 17.2 0.3 0.017 15.1 0.2 2.1 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily cNMP_binding PF00027.29 ORY29914.1 - 5.3e-08 32.8 0.1 1.9e-07 31.1 0.1 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Cupin_3 PF05899.12 ORY29914.1 - 0.017 14.8 0.1 0.031 13.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_2 PF07883.11 ORY29914.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Cupin domain Pkinase PF00069.25 ORY29915.1 - 0.0034 16.8 0.0 0.044 13.1 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 ORY29915.1 - 0.029 14.3 0.0 0.078 12.9 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 ORY29915.1 - 0.096 12.0 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PRK PF00485.18 ORY29916.1 - 0.023 14.4 0.1 0.046 13.4 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Mg_chelatase PF01078.21 ORY29916.1 - 0.14 11.5 0.0 9 5.6 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TrwB_AAD_bind PF10412.9 ORY29916.1 - 0.19 10.6 0.0 0.31 9.9 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Peptidase_M14 PF00246.24 ORY29917.1 - 1.8e-76 257.7 0.0 2.5e-76 257.3 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 ORY29917.1 - 5.7e-11 42.7 0.0 1.5e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 Carboxypeptidase activation peptide LOH1CR12 PF10158.9 ORY29918.1 - 4.8e-08 33.1 0.0 7.1e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Tumour suppressor protein Baculo_PEP_C PF04513.12 ORY29918.1 - 0.0031 17.5 1.4 0.0051 16.9 1.4 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus ArAE_2 PF10334.9 ORY29918.1 - 0.078 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 Zw10 PF06248.13 ORY29918.1 - 0.12 10.9 0.2 0.15 10.6 0.2 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 DUF948 PF06103.11 ORY29918.1 - 0.13 12.5 1.8 0.89 9.9 1.8 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) BMFP PF04380.13 ORY29918.1 - 0.16 12.5 0.3 0.27 11.7 0.3 1.4 1 0 0 1 1 1 0 Membrane fusogenic activity DUF2457 PF10446.9 ORY29918.1 - 0.38 9.8 3.5 0.48 9.5 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pet127 PF08634.10 ORY29919.1 - 1.6e-54 185.2 0.1 2.2e-54 184.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Rsm22 PF09243.10 ORY29922.1 - 7.3e-23 81.2 0.1 1.1e-22 80.6 0.1 1.3 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Mito_carr PF00153.27 ORY29923.1 - 6.2e-67 221.6 5.7 2.9e-24 84.8 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Acetyltransf_10 PF13673.7 ORY29924.1 - 0.002 18.1 0.0 0.0031 17.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY29924.1 - 0.018 15.3 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 ORY29924.1 - 0.098 12.7 0.0 0.6 10.2 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GDI PF00996.18 ORY29926.1 - 2.1e-27 95.7 0.0 2.7e-13 49.3 0.0 2.7 2 1 0 2 2 2 2 GDP dissociation inhibitor Gpi1 PF05024.15 ORY29927.1 - 2.9e-65 219.9 10.8 5.2e-65 219.0 10.8 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Velvet PF11754.8 ORY29928.1 - 2e-39 136.0 0.7 2.1e-37 129.4 0.7 2.2 1 1 0 1 1 1 1 Velvet factor RPEL PF02755.15 ORY29929.1 - 2.2e-13 49.4 13.2 0.0021 17.7 1.7 4.5 4 0 0 4 4 4 4 RPEL repeat Glyco_hydro_46 PF01374.18 ORY29930.1 - 2e-28 99.4 0.0 1.1e-27 97.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 46 Glyco_hydro_80 PF13647.6 ORY29930.1 - 0.0044 16.6 0.1 0.0066 16.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 80 of chitosanase A WD40 PF00400.32 ORY29931.1 - 6.5e-16 58.4 22.1 0.0015 19.3 0.9 6.2 5 1 1 6 6 6 5 WD domain, G-beta repeat Nucleotid_trans PF03407.16 ORY29933.1 - 2.6e-23 83.1 0.8 5.5e-16 59.2 0.1 2.5 2 0 0 2 2 2 2 Nucleotide-diphospho-sugar transferase YBD PF17725.1 ORY29933.1 - 0.094 12.6 0.0 8.9 6.1 0.0 2.2 2 0 0 2 2 2 0 YAP binding domain TauD PF02668.16 ORY29934.1 - 6.6e-46 157.3 0.2 8.5e-46 156.9 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Imm17 PF15562.6 ORY29935.1 - 0.0017 18.1 3.4 0.0022 17.8 2.5 1.7 1 1 1 2 2 2 2 Immunity protein 17 Nucleotid_trans PF03407.16 ORY29936.1 - 0.0002 21.4 0.9 0.00025 21.1 0.9 1.4 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase RabGAP-TBC PF00566.18 ORY29937.1 - 5.4e-29 101.4 0.0 9.6e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 ORY29937.1 - 1.1e-17 64.3 0.0 1.6e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY29937.1 - 2.6e-13 49.8 0.0 4.2e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Rhodanese PF00581.20 ORY29937.1 - 0.001 19.6 0.0 0.0026 18.2 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain LRR_8 PF13855.6 ORY29939.1 - 2.6e-25 87.9 29.9 1.6e-07 31.0 1.0 4.2 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY29939.1 - 1e-18 67.1 26.3 0.00027 21.3 2.1 5.4 2 1 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY29939.1 - 2.9e-07 30.1 22.9 0.32 11.7 0.4 8.3 7 1 1 8 8 8 2 Leucine Rich Repeat LRR_9 PF14580.6 ORY29939.1 - 2.6e-06 27.1 5.9 0.0032 17.0 0.6 2.8 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 ORY29939.1 - 0.058 13.5 15.6 1.2 9.4 0.1 6.1 6 0 0 6 6 6 0 Leucine Rich repeat LRR_8 PF13855.6 ORY29943.1 - 7.9e-09 35.1 9.9 9.7e-06 25.3 2.5 2.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY29943.1 - 0.0036 17.7 7.1 0.0053 17.2 1.6 2.8 1 1 1 2 2 2 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORY29943.1 - 0.012 15.2 0.4 0.033 13.7 0.1 1.7 1 1 0 2 2 2 0 Leucine-rich repeat LRR_2 PF07723.13 ORY29943.1 - 0.13 13.0 0.0 4.8 8.0 0.0 2.6 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_1 PF00560.33 ORY29943.1 - 2.1 9.2 6.5 54 4.9 0.8 4.1 3 1 0 3 3 3 0 Leucine Rich Repeat BET PF17035.5 ORY29945.1 - 2e-16 59.9 0.8 7.1e-16 58.1 0.8 2.1 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation LRR_6 PF13516.6 ORY29945.1 - 1.2e-06 28.1 18.5 6.1e-05 22.8 0.5 6.1 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 ORY29945.1 - 0.065 13.8 0.0 29 5.8 0.0 3.3 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_4 PF12799.7 ORY29945.1 - 0.11 12.9 3.3 3.9 8.0 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Arm-DNA-bind_1 PF09003.10 ORY29945.1 - 0.18 12.0 0.5 38 4.5 0.0 3.1 3 0 0 3 3 3 0 Bacteriophage lambda integrase, Arm DNA-binding domain PAP1 PF08601.10 ORY29945.1 - 5.8 6.5 7.5 40 3.8 0.0 2.6 2 1 0 2 2 2 0 Transcription factor PAP1 HSP70 PF00012.20 ORY30085.1 - 1.1e-76 258.4 12.1 3.4e-74 250.1 4.4 2.9 2 1 0 2 2 2 2 Hsp70 protein Vfa1 PF08432.10 ORY30085.1 - 0.082 13.2 5.2 0.18 12.1 5.2 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CPSF100_C PF13299.6 ORY30085.1 - 0.17 12.0 3.4 0.55 10.4 3.4 1.8 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 ORY30085.1 - 1.3 7.3 6.1 1.8 6.7 6.1 1.2 1 0 0 1 1 1 0 CDC45-like protein L31 PF09784.9 ORY30086.1 - 2.4e-23 82.5 0.6 2.9e-23 82.2 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 NAD_binding_2 PF03446.15 ORY30087.1 - 3.9e-13 49.9 0.2 5.5e-13 49.4 0.2 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ORY30087.1 - 1e-11 45.1 0.0 2.1e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase FHA PF00498.26 ORY30091.1 - 1.8e-16 60.2 0.0 3.5e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 ORY30091.1 - 9.6e-10 38.7 0.0 2.1e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain dsrm PF00035.26 ORY30091.1 - 2.3e-08 34.6 0.6 7.9e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 Double-stranded RNA binding motif Dicer_dimer PF03368.14 ORY30091.1 - 0.011 15.9 0.0 0.03 14.5 0.0 1.8 1 0 0 1 1 1 0 Dicer dimerisation domain CK2S PF15011.6 ORY30091.1 - 0.068 13.0 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Casein Kinase 2 substrate DUF640 PF04852.12 ORY30092.1 - 0.0061 16.7 0.0 0.01 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF640) Rhodanese_C PF12368.8 ORY30093.1 - 0.009 16.4 1.0 0.011 16.1 1.0 1.2 1 0 0 1 1 1 1 Rhodanase C-terminal Otopetrin PF03189.13 ORY30094.1 - 0.027 13.3 0.2 0.13 11.1 0.2 2.3 1 1 0 1 1 1 0 Otopetrin HELP PF03451.14 ORY30095.1 - 1.9e-12 46.8 0.0 3.7e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 HELP motif WD40 PF00400.32 ORY30095.1 - 0.14 13.1 1.4 2.3 9.2 0.1 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat WD40 PF00400.32 ORY30096.1 - 8.4e-21 73.9 9.7 0.00024 21.8 0.1 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY30096.1 - 1.4e-11 44.6 0.0 0.0062 16.8 0.0 4.5 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 ORY30096.1 - 0.00095 17.8 0.0 0.0036 15.9 0.0 1.8 2 0 0 2 2 2 1 Cytochrome D1 heme domain PD40 PF07676.12 ORY30096.1 - 0.033 14.1 0.0 4 7.5 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat LRR_9 PF14580.6 ORY30097.1 - 4.9e-10 39.2 0.1 8.3e-10 38.4 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 ORY30097.1 - 2.8e-06 27.6 5.3 0.00078 19.8 0.6 3.3 1 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY30097.1 - 3.2e-06 26.8 7.4 0.0003 20.5 1.2 2.1 1 1 1 2 2 2 2 Leucine rich repeat SURF6 PF04935.12 ORY30097.1 - 0.099 12.4 4.0 0.16 11.8 4.0 1.2 1 0 0 1 1 1 0 Surfeit locus protein 6 DUF4187 PF13821.6 ORY30098.1 - 2.8e-19 68.6 0.8 6.9e-19 67.4 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 ORY30098.1 - 5.1e-05 23.1 2.0 0.0002 21.2 2.0 2.1 1 1 0 1 1 1 1 G-patch domain G6B PF15096.6 ORY30098.1 - 0.14 11.9 4.8 0.34 10.7 0.1 2.1 2 0 0 2 2 2 0 G6B family G-patch_2 PF12656.7 ORY30098.1 - 1.1 9.5 5.1 0.28 11.3 0.3 2.6 3 0 0 3 3 3 0 G-patch domain SPA PF08616.10 ORY30099.1 - 3.9e-05 23.6 0.0 8.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Phostensin_N PF13916.6 ORY30100.1 - 0.14 12.5 1.7 9.2 6.7 0.0 2.7 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal DUF4400 PF14348.6 ORY30100.1 - 0.39 10.2 1.2 0.65 9.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) Gti1_Pac2 PF09729.9 ORY30101.1 - 1e-21 77.8 7.4 1.8e-21 77.1 0.3 3.3 3 1 0 3 3 3 1 Gti1/Pac2 family KDZ PF18758.1 ORY30102.1 - 7.4e-19 68.2 0.0 1e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Peptidase_M14 PF00246.24 ORY30103.1 - 0.048 13.4 0.0 0.08 12.7 0.0 1.3 1 1 0 1 1 1 0 Zinc carboxypeptidase CcdB PF01845.17 ORY30104.1 - 0.062 13.5 1.1 1.9 8.8 0.1 2.2 1 1 1 2 2 2 0 CcdB protein CENP-Q PF13094.6 ORY30104.1 - 0.077 13.2 0.3 0.11 12.7 0.3 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit ABC_membrane PF00664.23 ORY30105.1 - 9e-25 87.8 12.2 9e-25 87.8 12.2 1.3 2 0 0 2 2 2 1 ABC transporter transmembrane region Reo_P9 PF06043.11 ORY30105.1 - 0.051 13.0 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Reovirus P9-like family HTH_Tnp_4 PF13613.6 ORY30106.1 - 0.071 12.8 0.8 0.93 9.3 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix of DDE superfamily endonuclease SPW PF03779.14 ORY30106.1 - 0.36 10.4 1.7 0.79 9.4 0.2 2.0 2 0 0 2 2 2 0 SPW repeat ABC_tran PF00005.27 ORY30107.1 - 1e-30 107.0 0.0 2e-30 106.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ORY30107.1 - 7e-29 101.3 10.3 7e-29 101.3 10.3 2.1 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 ORY30107.1 - 6.5e-07 29.0 1.3 5.2e-05 22.8 1.3 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY30107.1 - 0.01 15.9 0.7 0.021 14.9 0.1 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_21 PF13304.6 ORY30107.1 - 0.02 14.7 0.2 2.3 7.9 0.2 2.4 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 ORY30107.1 - 0.074 13.1 0.4 0.18 11.8 0.4 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain PRKCSH-like PF12999.7 ORY30108.1 - 3e-47 160.6 3.5 3e-47 160.6 3.5 2.6 2 1 1 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 ORY30108.1 - 2.4e-21 76.0 0.1 4e-21 75.3 0.1 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 ORY30108.1 - 2.6e-06 28.4 1.7 6.7e-06 27.0 1.7 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 ORY30108.1 - 0.0035 17.5 2.2 0.0035 17.5 2.2 3.0 3 0 0 3 3 3 1 Low-density lipoprotein receptor domain class A APG6_N PF17675.1 ORY30108.1 - 0.075 13.6 8.9 0.17 12.4 8.9 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 ORY30108.1 - 0.24 11.2 2.9 0.49 10.2 2.9 1.5 1 0 0 1 1 1 0 Septum formation initiator Zn_clus PF00172.18 ORY30109.1 - 0.003 17.7 11.5 0.003 17.7 11.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain An_peroxidase PF03098.15 ORY30110.1 - 6.2e-33 114.2 0.5 4.4e-25 88.3 0.2 3.8 1 1 1 2 2 2 2 Animal haem peroxidase MFS_1 PF07690.16 ORY30111.1 - 1e-51 175.9 53.9 8.9e-35 120.2 24.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY30111.1 - 5.3e-06 25.6 35.5 0.0019 17.1 4.0 3.6 2 2 2 4 4 4 3 Sugar (and other) transporter MFS_4 PF06779.14 ORY30111.1 - 5.7e-06 25.9 23.7 0.017 14.5 7.1 3.1 2 1 1 3 3 3 3 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 ORY30111.1 - 3.2e-05 23.0 26.2 0.0021 17.0 9.3 3.2 1 1 2 3 3 3 2 MFS_1 like family MFS_2 PF13347.6 ORY30111.1 - 0.00056 18.6 6.0 0.00056 18.6 6.0 3.1 2 2 1 3 3 3 2 MFS/sugar transport protein RNase_H PF00075.24 ORY30112.1 - 2.1e-41 141.4 0.1 3.7e-41 140.7 0.0 1.4 2 0 0 2 2 2 1 RNase H Myb_DNA-binding PF00249.31 ORY30113.1 - 8.5e-11 41.9 11.5 0.11 12.7 0.2 7.7 8 0 0 8 8 8 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY30113.1 - 1.2e-06 28.7 7.6 0.13 12.6 0.1 6.1 6 1 1 7 7 7 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 ORY30113.1 - 0.079 13.2 0.0 48 4.2 0.0 3.8 4 0 0 4 4 4 0 Rap1 Myb domain HMG_box PF00505.19 ORY30114.1 - 1.6e-09 38.0 0.8 4.1e-09 36.7 0.8 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY30114.1 - 2.3e-07 31.3 2.2 5.4e-07 30.1 1.4 2.1 2 1 0 2 2 2 1 HMG-box domain RhlB PF12300.8 ORY30114.1 - 0.12 12.6 3.6 0.24 11.5 0.5 2.1 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB RP-C_C PF11800.8 ORY30114.1 - 0.23 11.6 10.8 0.04 14.0 6.8 1.7 1 1 1 2 2 2 0 Replication protein C C-terminal region SPOUT_MTase PF02590.17 ORY30114.1 - 0.32 11.0 2.2 0.45 10.5 0.6 1.8 1 1 0 2 2 2 0 Predicted SPOUT methyltransferase Dicty_REP PF05086.12 ORY30114.1 - 0.73 7.7 7.6 0.91 7.4 7.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RR_TM4-6 PF06459.12 ORY30114.1 - 5.1 6.8 12.1 6.7 6.4 12.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 YL1 PF05764.13 ORY30115.1 - 0.0052 16.9 12.1 0.0079 16.3 12.1 1.2 1 0 0 1 1 1 1 YL1 nuclear protein PBP1_TM PF14812.6 ORY30115.1 - 0.012 16.0 3.4 0.012 16.0 3.4 2.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIIF_alpha PF05793.12 ORY30115.1 - 0.37 9.3 25.3 0.46 9.0 25.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 ORY30115.1 - 0.63 8.3 2.3 0.73 8.1 2.3 1.2 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.10 ORY30115.1 - 0.99 9.8 12.8 2 8.8 12.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 ORY30115.1 - 1.4 8.1 6.7 2.7 7.2 6.7 1.4 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 ORY30115.1 - 2.5 7.7 6.5 0.26 11.0 0.8 2.0 2 1 0 2 2 2 0 FAM176 family PGA2 PF07543.12 ORY30115.1 - 2.6 8.0 7.9 7.2 6.6 0.6 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 Cwf_Cwc_15 PF04889.12 ORY30115.1 - 5.4 6.7 14.7 0.46 10.2 6.9 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein RXT2_N PF08595.11 ORY30115.1 - 6.4 6.8 7.2 0.28 11.2 0.9 1.9 2 1 0 2 2 2 0 RXT2-like, N-terminal HMG_box PF00505.19 ORY30116.1 - 0.00012 22.4 5.2 0.022 15.2 0.2 2.9 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY30116.1 - 0.0005 20.6 7.6 0.034 14.7 0.2 3.4 3 0 0 3 3 3 2 HMG-box domain DUF3106 PF11304.8 ORY30116.1 - 0.077 13.5 5.2 0.39 11.2 0.1 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3106) DUF3681 PF12442.8 ORY30117.1 - 0.33 11.5 2.7 2 8.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) Endonuclease_NS PF01223.23 ORY30118.1 - 4.7e-58 196.7 0.0 6.7e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease rpo132 PF12415.8 ORY30118.1 - 0.14 11.5 0.1 0.26 10.6 0.1 1.4 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase NICE-3 PF07406.11 ORY30119.1 - 0.35 10.8 0.2 0.35 10.8 0.2 1.7 2 0 0 2 2 2 0 NICE-3 protein MIG-14_Wnt-bd PF06664.12 ORY30119.1 - 0.76 8.9 13.6 1.2 8.3 13.6 1.3 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion DHHC PF01529.20 ORY30119.1 - 3.2 7.8 17.1 0.66 10.1 7.1 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase Phage_holin_1 PF04531.13 ORY30119.1 - 3.6 8.2 11.9 47 4.6 8.5 2.6 1 1 2 3 3 3 0 Bacteriophage holin DUF3810 PF12725.7 ORY30119.1 - 6 6.1 7.1 0.61 9.4 2.4 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) DPM3 PF08285.11 ORY30119.1 - 8.5 6.6 7.7 0.61 10.3 2.5 1.8 2 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) LRR_4 PF12799.7 ORY30121.1 - 7.6e-18 64.3 14.9 8.9e-05 22.8 0.3 5.0 4 2 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY30121.1 - 6.3e-15 54.7 31.5 2e-07 30.6 2.2 3.9 2 1 3 5 5 5 5 Leucine rich repeat LRR_1 PF00560.33 ORY30121.1 - 2e-05 24.5 20.2 3 8.8 0.0 8.0 8 2 0 8 8 8 3 Leucine Rich Repeat LRR_6 PF13516.6 ORY30121.1 - 0.7 10.1 18.9 14 6.0 0.0 6.5 7 0 0 7 7 7 0 Leucine Rich repeat LIM PF00412.22 ORY30122.1 - 3.8e-08 33.4 10.8 5.5e-08 32.9 10.8 1.2 1 0 0 1 1 1 1 LIM domain zinc_ribbon_2 PF13240.6 ORY30122.1 - 0.13 12.0 0.5 0.13 12.0 0.5 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-ACC PF17848.1 ORY30122.1 - 1.8 8.7 5.6 14 5.8 0.4 2.4 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain RdRP PF05183.12 ORY30123.1 - 1.9e-161 538.7 0.0 2.4e-161 538.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase LRR_8 PF13855.6 ORY30124.1 - 5.3e-18 64.5 42.9 3.5e-07 29.9 6.9 5.3 3 1 5 8 8 8 6 Leucine rich repeat LRR_4 PF12799.7 ORY30124.1 - 2e-12 47.1 29.4 3.6e-06 27.2 6.9 5.5 4 3 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY30124.1 - 1.2e-11 43.4 18.6 0.15 12.7 0.1 8.3 8 0 0 8 8 8 5 Leucine Rich Repeat LRR_2 PF07723.13 ORY30124.1 - 0.073 13.8 3.8 75 4.2 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 ORY30124.1 - 6.1 7.2 31.9 0.47 10.6 0.3 6.9 8 0 0 8 8 8 0 Leucine Rich repeat Gti1_Pac2 PF09729.9 ORY30125.1 - 2.1e-18 67.1 0.2 3.5e-13 50.0 0.0 2.7 2 1 1 3 3 3 2 Gti1/Pac2 family Peptidase_S41 PF03572.18 ORY30127.1 - 2.9e-05 23.7 0.0 6.3e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase family S41 RdRP PF05183.12 ORY30129.1 - 7.8e-62 209.7 0.0 8.4e-40 137.0 0.0 2.0 1 1 1 2 2 2 2 RNA dependent RNA polymerase Peptidase_M48_N PF16491.5 ORY30131.1 - 5.5e-60 202.4 7.4 5.5e-60 202.4 7.4 1.9 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 ORY30131.1 - 3.7e-48 163.9 0.0 7.4e-48 162.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.9 ORY30131.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 Predicted Zn-dependent protease (DUF2268) SprT-like PF10263.9 ORY30131.1 - 0.019 14.8 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 SprT-like family Tetraspanin PF00335.20 ORY30131.1 - 2 8.1 4.6 2.6 7.7 3.2 1.9 2 0 0 2 2 2 0 Tetraspanin family Peptidase_M56 PF05569.11 ORY30131.1 - 6.5 5.8 9.1 8.2 5.5 5.7 2.7 1 1 1 2 2 2 0 BlaR1 peptidase M56 LRR_8 PF13855.6 ORY30132.1 - 2.6e-28 97.6 36.9 1.6e-10 40.6 3.4 4.6 4 1 0 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 ORY30132.1 - 1.2e-20 73.2 36.4 2.4e-06 27.8 1.3 5.4 4 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY30132.1 - 1.9e-14 52.0 39.8 0.15 12.7 0.2 10.3 9 1 2 11 11 11 7 Leucine Rich Repeat LRR_6 PF13516.6 ORY30132.1 - 8.6e-06 25.4 39.3 0.69 10.1 0.1 8.4 10 0 0 10 10 10 5 Leucine Rich repeat LRR_9 PF14580.6 ORY30132.1 - 0.0065 16.0 7.8 0.15 11.5 0.2 3.1 1 1 2 3 3 3 2 Leucine-rich repeat Pou PF00157.17 ORY30132.1 - 0.04 13.9 0.2 4.7 7.3 0.0 2.8 3 0 0 3 3 3 0 Pou domain - N-terminal to homeobox domain LRR_2 PF07723.13 ORY30132.1 - 0.12 13.0 9.2 37 5.2 0.0 6.6 9 0 0 9 9 9 0 Leucine Rich Repeat Glyco_transf_34 PF05637.12 ORY30133.1 - 1.2e-12 48.1 0.7 9.2e-08 32.1 0.4 2.1 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.14 ORY30133.1 - 1.4e-05 24.8 0.0 2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF273 Nucleotid_trans PF03407.16 ORY30133.1 - 0.13 12.2 0.4 0.21 11.5 0.4 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase YL1 PF05764.13 ORY30134.1 - 0.23 11.5 5.0 0.29 11.2 5.0 1.0 1 0 0 1 1 1 0 YL1 nuclear protein SDA1 PF05285.12 ORY30134.1 - 0.46 9.9 6.5 0.56 9.6 6.5 1.1 1 0 0 1 1 1 0 SDA1 CENP-B_dimeris PF09026.10 ORY30134.1 - 1.4 9.4 13.3 0.73 10.3 3.1 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Ysc84 PF04366.12 ORY30135.1 - 8.1e-16 57.9 0.0 4e-14 52.5 0.0 2.1 1 1 1 2 2 2 2 Las17-binding protein actin regulator PhoLip_ATPase_C PF16212.5 ORY30136.1 - 0.00022 21.0 5.7 0.00026 20.8 5.7 1.0 1 0 0 1 1 1 1 Phospholipid-translocating P-type ATPase C-terminal DUF4173 PF13777.6 ORY30136.1 - 0.01 15.3 1.0 0.011 15.1 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4173) Gti1_Pac2 PF09729.9 ORY30139.1 - 3.1e-11 43.7 3.9 5.9e-07 29.7 0.0 3.0 3 0 0 3 3 3 2 Gti1/Pac2 family Shugoshin_C PF07557.11 ORY30139.1 - 0.055 13.3 1.8 0.095 12.5 1.8 1.4 1 0 0 1 1 1 0 Shugoshin C terminus SOCS PF12610.8 ORY30139.1 - 0.15 12.5 1.3 0.24 11.8 1.3 1.3 1 0 0 1 1 1 0 Suppressor of cytokine signalling Gti1_Pac2 PF09729.9 ORY30141.1 - 5e-25 88.6 0.2 2.6e-19 70.0 0.0 3.0 2 1 1 3 3 3 2 Gti1/Pac2 family Gti1_Pac2 PF09729.9 ORY30143.1 - 2.5e-06 27.7 0.1 8.6e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 Gti1/Pac2 family zf-C2H2 PF00096.26 ORY30145.1 - 3.3e-13 49.3 12.4 0.0011 19.3 0.4 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY30145.1 - 6.6e-13 48.4 15.4 0.0005 20.4 0.4 3.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY30145.1 - 3.7e-10 39.8 13.2 0.0092 16.7 0.4 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY30145.1 - 1.1e-09 38.0 11.4 5.1e-05 23.2 0.4 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY30145.1 - 1.1e-05 25.6 12.0 0.37 11.1 0.0 4.5 4 1 1 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 ORY30145.1 - 0.00029 21.2 10.5 0.061 13.8 0.4 3.1 1 1 2 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 ORY30145.1 - 0.0022 18.3 9.2 0.99 9.8 0.4 3.0 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) DUF3268 PF11672.8 ORY30145.1 - 0.0025 18.1 0.4 0.48 10.8 0.2 2.1 1 1 1 2 2 2 1 zinc-finger-containing domain zf-met PF12874.7 ORY30145.1 - 0.0086 16.4 8.4 1.5 9.4 0.4 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 ORY30145.1 - 0.009 16.1 5.9 0.55 10.4 3.3 3.0 2 1 1 3 3 3 1 Zinc ribbon domain zinc_ribbon_5 PF13719.6 ORY30145.1 - 0.016 15.0 4.9 10 6.0 0.1 3.4 3 1 0 3 3 3 0 zinc-ribbon domain zf_C2H2_ZHX PF18387.1 ORY30145.1 - 0.028 14.1 10.0 0.97 9.1 0.2 3.1 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain GAGA PF09237.11 ORY30145.1 - 0.03 14.1 5.5 4.3 7.2 0.4 3.1 1 1 2 3 3 3 0 GAGA factor zf-C2H2_12 PF18658.1 ORY30145.1 - 0.081 12.5 0.2 0.081 12.5 0.2 2.1 1 1 2 3 3 3 0 Zinc-finger C2H2-type zf-BED PF02892.15 ORY30145.1 - 0.092 12.8 8.1 4.4 7.4 0.4 3.2 1 1 1 2 2 2 0 BED zinc finger Baculo_IE-1 PF05290.11 ORY30145.1 - 0.094 12.7 1.7 14 5.7 0.0 2.8 1 1 2 3 3 3 0 Baculovirus immediate-early protein (IE-0) FYVE PF01363.21 ORY30145.1 - 0.1 12.7 7.3 7.7 6.7 3.7 2.9 2 1 0 2 2 2 0 FYVE zinc finger zf-C2H2_3rep PF18868.1 ORY30145.1 - 0.14 12.9 4.7 2.3 8.9 4.2 2.4 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-MYST PF17772.1 ORY30145.1 - 0.18 11.4 1.5 4.7 6.9 0.0 2.8 1 1 2 3 3 3 0 MYST family zinc finger domain zf-AN1 PF01428.16 ORY30145.1 - 0.61 10.3 6.6 9.6 6.5 0.2 3.2 3 0 0 3 3 3 0 AN1-like Zinc finger Actin_micro PF17003.5 ORY30145.1 - 0.75 8.9 5.8 3.7 6.6 2.3 2.6 1 1 1 2 2 2 0 Putative actin-like family zf-DBF PF07535.12 ORY30145.1 - 0.77 9.9 6.7 7.2 6.8 0.5 3.1 3 0 0 3 3 3 0 DBF zinc finger DUF629 PF04780.12 ORY30145.1 - 0.91 8.0 6.5 0.88 8.0 0.4 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF629) zf-C4 PF00105.18 ORY30145.1 - 1.6 9.2 6.8 5.4 7.6 0.3 2.8 1 1 0 2 2 2 0 Zinc finger, C4 type (two domains) LisH_2 PF16045.5 ORY30146.1 - 4.5e-10 38.4 0.0 7.7e-10 37.6 0.0 1.4 1 0 0 1 1 1 1 LisH FOP_dimer PF09398.10 ORY30146.1 - 0.0088 16.3 0.0 0.045 14.0 0.0 2.3 1 0 0 1 1 1 1 FOP N terminal dimerisation domain bZIP_1 PF00170.21 ORY30147.1 - 2.2e-08 34.1 12.2 4.5e-06 26.7 6.2 2.4 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 ORY30147.1 - 0.026 14.6 19.4 0.26 11.4 8.0 2.8 3 0 0 3 3 3 0 Basic region leucine zipper Shugoshin_N PF07558.11 ORY30147.1 - 0.036 13.9 0.6 0.89 9.5 0.1 2.5 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region PKcGMP_CC PF16808.5 ORY30147.1 - 0.081 12.8 2.9 0.15 11.9 0.2 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1690 PF07956.11 ORY30147.1 - 0.11 12.9 13.0 0.035 14.5 9.7 1.7 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) M PF02370.16 ORY30147.1 - 0.57 10.9 11.5 1.5 9.6 1.4 3.3 3 0 0 3 3 3 0 M protein repeat bZIP_1 PF00170.21 ORY30148.1 - 1.2e-08 34.9 12.1 5.6e-06 26.3 6.1 2.3 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 ORY30148.1 - 0.00066 19.7 13.9 0.16 12.1 8.1 2.3 2 0 0 2 2 2 2 Basic region leucine zipper HAP1_N PF04849.13 ORY30148.1 - 0.00092 18.5 6.5 0.0016 17.8 6.5 1.4 1 1 0 1 1 1 1 HAP1 N-terminal conserved region DUF1690 PF07956.11 ORY30148.1 - 0.01 16.3 12.6 0.016 15.6 12.6 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) TSC22 PF01166.18 ORY30148.1 - 0.017 15.4 1.4 0.1 12.9 0.1 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family PKcGMP_CC PF16808.5 ORY30148.1 - 0.1 12.4 2.7 0.16 11.9 0.2 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase M PF02370.16 ORY30148.1 - 0.22 12.2 6.6 3 8.7 0.5 2.7 2 0 0 2 2 2 0 M protein repeat bZIP_Maf PF03131.17 ORY30148.1 - 5.9 7.5 15.7 15 6.2 14.9 1.9 1 1 1 2 2 2 0 bZIP Maf transcription factor zf-C2H2 PF00096.26 ORY30149.1 - 3.7e-13 49.1 11.2 0.00011 22.5 1.4 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY30149.1 - 1.4e-09 38.0 9.4 0.032 15.1 0.1 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY30149.1 - 2.6e-06 27.6 3.7 0.0016 18.6 0.1 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 ORY30149.1 - 0.00044 20.5 12.5 0.035 14.5 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.7 ORY30149.1 - 0.00057 20.2 5.4 0.092 13.2 0.1 3.4 2 1 1 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 ORY30149.1 - 0.002 18.4 2.2 0.0063 16.8 2.2 1.8 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf_ZIC PF18366.1 ORY30149.1 - 0.0022 18.1 1.7 0.79 9.9 0.1 3.1 2 1 1 3 3 3 1 Zic proteins zinc finger domain Ogr_Delta PF04606.12 ORY30149.1 - 0.0032 17.4 0.4 1.3 9.1 0.0 2.4 1 1 1 2 2 2 2 Ogr/Delta-like zinc finger zf-C2H2_6 PF13912.6 ORY30149.1 - 0.0061 16.5 4.9 0.58 10.2 0.2 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORY30149.1 - 0.0098 16.1 1.9 0.38 10.9 0.0 2.7 1 1 2 3 3 3 1 Aberrant zinc-finger zf-C2HC_2 PF13913.6 ORY30149.1 - 0.12 12.4 0.7 0.12 12.4 0.7 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type FOXP-CC PF16159.5 ORY30149.1 - 0.24 12.1 7.8 4.2 8.1 0.4 3.1 2 1 1 3 3 3 0 FOXP coiled-coil domain Zn-ribbon_8 PF09723.10 ORY30149.1 - 0.28 11.3 5.5 19 5.5 0.1 3.2 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2H2_11 PF16622.5 ORY30149.1 - 2.4 8.0 6.2 25 4.7 1.2 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type SfLAP PF11139.8 ORY30150.1 - 0.094 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein CPSase_L_D2 PF02786.17 ORY30151.1 - 1.1e-111 371.4 0.2 2.6e-82 275.4 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 ORY30151.1 - 1.6e-45 154.1 0.0 3.8e-45 152.8 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 ORY30151.1 - 9.3e-45 152.7 0.0 2.1e-44 151.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 ORY30151.1 - 4.2e-43 146.9 0.0 1.2e-42 145.4 0.0 1.9 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 ORY30151.1 - 2.8e-40 137.5 0.1 9.2e-40 135.8 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 ORY30151.1 - 2.3e-34 118.8 0.1 2.3e-34 118.8 0.1 2.1 3 0 0 3 3 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 ORY30151.1 - 2.1e-18 66.3 0.0 1.4e-17 63.6 0.0 2.6 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 ORY30151.1 - 7e-16 58.4 0.4 2.7e-07 30.3 0.1 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORY30151.1 - 9.5e-16 57.8 0.1 1.8e-07 30.9 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 ORY30151.1 - 2.8e-09 36.8 0.0 0.0004 20.1 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 ORY30151.1 - 7.3e-05 22.6 0.0 0.03 14.1 0.0 2.7 2 0 0 2 2 2 2 Peptidase C26 ATP-grasp_3 PF02655.14 ORY30151.1 - 0.00046 20.3 0.3 1 9.4 0.1 2.8 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.24 ORY30151.1 - 0.012 15.4 0.3 1.2 8.9 0.0 3.6 5 0 0 5 5 5 0 DJ-1/PfpI family TrkA_N PF02254.18 ORY30151.1 - 0.037 14.3 0.1 0.24 11.7 0.0 2.4 3 0 0 3 3 2 0 TrkA-N domain IMPDH PF00478.25 ORY30152.1 - 4.1e-46 157.6 11.3 3.7e-45 154.4 11.3 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Aldolase PF01081.19 ORY30152.1 - 0.0029 17.1 0.5 0.043 13.2 0.1 2.1 2 0 0 2 2 2 1 KDPG and KHG aldolase FMN_dh PF01070.18 ORY30152.1 - 0.11 11.5 6.2 0.15 11.0 6.2 1.4 1 1 0 1 1 1 0 FMN-dependent dehydrogenase Gti1_Pac2 PF09729.9 ORY30154.1 - 5.5e-20 72.2 5.0 1e-15 58.3 0.0 3.1 3 1 1 4 4 4 2 Gti1/Pac2 family PhoLip_ATPase_C PF16212.5 ORY30157.1 - 0.019 14.8 8.0 0.022 14.5 8.0 1.1 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal DUF4173 PF13777.6 ORY30157.1 - 0.033 13.6 4.3 0.047 13.1 4.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4173) T6SS_VasJ PF16989.5 ORY30158.1 - 0.047 13.2 0.0 0.047 13.2 0.0 1.1 1 0 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ Glyco_transf_20 PF00982.21 ORY30162.1 - 6.5e-157 523.0 0.0 8.3e-157 522.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 ORY30162.1 - 2.7e-70 236.1 0.0 4.3e-70 235.5 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 ORY30162.1 - 0.012 15.4 0.0 0.58 9.8 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Pox_D2 PF04701.13 ORY30163.1 - 0.031 14.5 0.1 0.064 13.4 0.1 1.5 1 0 0 1 1 1 0 Pox virus D2 protein TIR-like PF10137.9 ORY30164.1 - 0.026 14.5 0.4 0.14 12.1 0.3 2.3 3 0 0 3 3 3 0 Predicted nucleotide-binding protein containing TIR-like domain DUF2321 PF10083.9 ORY30164.1 - 0.07 12.8 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) TIR_2 PF13676.6 ORY30164.1 - 0.11 13.1 0.2 0.39 11.3 0.2 1.9 1 0 0 1 1 1 0 TIR domain AMMECR1 PF01871.17 ORY30165.1 - 2.6e-46 157.3 0.0 3e-46 157.1 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 Ammonium_transp PF00909.21 ORY30292.1 - 5e-45 153.9 13.0 6e-45 153.6 13.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF2568 PF10823.8 ORY30292.1 - 1.8 8.9 16.6 0.8 10.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2568) Ammonium_transp PF00909.21 ORY30293.1 - 2.9e-82 276.5 23.0 3.3e-82 276.3 23.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family B9-C2 PF07162.11 ORY30294.1 - 2.3e-51 174.3 0.0 2.6e-51 174.2 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein F-box PF00646.33 ORY30295.1 - 1.4e-05 24.8 0.4 3.2e-05 23.7 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY30295.1 - 0.00028 20.7 0.1 0.00028 20.7 0.1 1.9 2 0 0 2 2 2 1 F-box-like Rad1 PF02144.16 ORY30295.1 - 0.12 11.4 0.2 0.16 11.0 0.2 1.2 1 0 0 1 1 1 0 Repair protein Rad1/Rec1/Rad17 F-box_4 PF15966.5 ORY30296.1 - 0.011 15.7 0.1 0.024 14.5 0.1 1.6 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 ORY30296.1 - 0.63 10.0 2.7 0.73 9.8 0.3 2.5 2 0 0 2 2 2 0 F-box-like GPI-anchored PF10342.9 ORY30297.1 - 0.025 15.3 2.5 0.055 14.2 0.7 2.5 1 1 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mucin PF01456.17 ORY30297.1 - 0.22 11.5 12.5 0.43 10.6 12.5 1.5 1 1 0 1 1 1 0 Mucin-like glycoprotein Tic110 PF16940.5 ORY30297.1 - 7.6 4.9 4.7 8.2 4.8 4.7 1.2 1 0 0 1 1 1 0 Chloroplast envelope transporter Stanniocalcin PF03298.13 ORY30298.1 - 0.00035 20.0 0.4 0.00044 19.6 0.4 1.1 1 0 0 1 1 1 1 Stanniocalcin family Mannosyl_trans3 PF11051.8 ORY30299.1 - 8.8e-40 136.8 0.0 1.9e-39 135.7 0.0 1.5 1 1 0 1 1 1 1 Mannosyltransferase putative TTL PF03133.15 ORY30300.1 - 5.2e-77 258.9 4.4 9.9e-77 257.9 0.9 2.6 2 1 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 ORY30300.1 - 7.3e-08 32.0 0.1 0.00052 19.3 0.0 3.3 2 2 0 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 ORY30300.1 - 0.00012 21.5 0.0 0.042 13.1 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 ORY30300.1 - 0.00072 19.6 0.0 0.004 17.2 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain Stm1_N PF09598.10 ORY30301.1 - 0.0023 18.8 8.0 0.0023 18.8 8.0 3.4 4 1 1 5 5 5 1 Stm1 DUF410 PF04190.13 ORY30301.1 - 0.063 13.1 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF410) zf-H2C2_2 PF13465.6 ORY30302.1 - 3.5e-15 55.6 19.9 2.1e-07 31.0 0.5 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORY30302.1 - 6e-10 39.0 25.9 0.00019 21.7 1.6 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY30302.1 - 3e-09 36.9 23.7 0.00063 20.4 0.7 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY30302.1 - 2.7e-05 24.3 4.1 0.0009 19.5 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORY30302.1 - 0.0011 19.2 2.3 0.0011 19.2 2.3 2.6 2 1 1 3 3 3 1 C2H2-type zinc ribbon zf-met PF12874.7 ORY30302.1 - 0.01 16.2 8.5 0.019 15.4 0.8 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 ORY30302.1 - 0.037 13.8 1.5 4.5 7.1 0.2 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 ORY30302.1 - 0.061 13.3 4.8 0.79 9.8 0.3 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 ORY30302.1 - 0.12 12.7 7.2 9 6.7 0.0 2.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CMD PF02627.20 ORY30302.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family zf_PR_Knuckle PF18445.1 ORY30302.1 - 1.6 8.6 6.6 0.36 10.7 0.7 2.7 3 0 0 3 3 3 0 PR zinc knuckle motif zf-H2C2_5 PF13909.6 ORY30302.1 - 4.5 7.1 15.8 0.13 12.0 3.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 ORY30303.1 - 1.5e-11 44.1 18.7 0.00098 19.5 5.0 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY30303.1 - 1.9e-10 40.7 7.6 3e-06 27.4 3.9 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY30303.1 - 7.3e-08 32.6 16.3 0.002 18.8 3.5 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY30303.1 - 0.00036 20.7 0.2 0.15 12.4 0.4 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY30303.1 - 0.034 14.1 1.7 0.034 14.1 1.7 3.5 4 1 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORY30303.1 - 0.25 11.1 0.2 0.25 11.1 0.2 4.1 5 0 0 5 5 5 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 ORY30303.1 - 0.76 10.3 5.4 2.5 8.6 0.4 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 ORY30303.1 - 2 8.1 6.3 4.8 6.9 0.3 2.3 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 ORY30304.1 - 1e-24 85.6 36.4 0.00023 21.5 0.7 7.5 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY30304.1 - 6.4e-17 60.8 35.9 0.0019 18.8 0.7 7.4 7 0 0 7 7 7 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY30304.1 - 9.9e-16 57.4 36.8 6.4e-05 23.2 0.1 7.6 9 0 0 9 9 7 4 Zinc-finger double domain zf-C2H2_8 PF15909.5 ORY30304.1 - 2e-08 34.4 17.2 0.00085 19.6 1.9 3.9 2 1 0 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 ORY30304.1 - 5.4e-05 23.4 16.3 0.35 11.2 0.9 5.5 5 1 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY30304.1 - 7.1e-05 23.1 11.3 0.19 12.1 1.1 5.3 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY30304.1 - 0.00037 20.4 36.2 0.02 14.9 1.7 6.8 7 0 0 7 7 7 3 C2H2-type zinc finger IBR PF01485.21 ORY30304.1 - 0.003 17.7 18.4 0.06 13.6 1.2 4.1 2 1 2 4 4 4 2 IBR domain, a half RING-finger domain zf-C2H2_11 PF16622.5 ORY30304.1 - 0.024 14.4 10.4 0.99 9.2 0.0 4.2 4 0 0 4 4 3 0 zinc-finger C2H2-type FOXP-CC PF16159.5 ORY30304.1 - 0.11 13.2 15.3 4.5 8.0 0.5 4.8 4 1 0 4 4 4 0 FOXP coiled-coil domain Rep_fac-A_C PF08646.10 ORY30304.1 - 0.12 12.1 3.4 2.9 7.6 0.1 2.6 2 1 0 2 2 2 0 Replication factor-A C terminal domain zf-C2H2_7 PF15269.6 ORY30304.1 - 0.21 11.7 10.5 1.7 8.8 0.2 4.6 4 0 0 4 4 4 0 Zinc-finger C1_4 PF07975.12 ORY30304.1 - 0.32 11.3 11.1 1.3 9.3 0.1 3.4 3 0 0 3 3 3 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 ORY30304.1 - 0.38 10.9 20.7 2.6 8.2 0.7 4.6 3 1 1 4 4 4 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 ORY30304.1 - 0.62 10.0 4.7 39 4.3 0.1 3.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_2 PF12756.7 ORY30304.1 - 0.69 10.3 21.5 0.34 11.3 0.5 4.5 3 2 3 6 6 5 0 C2H2 type zinc-finger (2 copies) zf-RING_7 PF02591.15 ORY30304.1 - 0.75 10.0 2.9 23 5.3 0.2 3.2 3 0 0 3 3 2 0 C4-type zinc ribbon domain Ndc1_Nup PF09531.10 ORY30304.1 - 1.2 7.8 3.4 1.5 7.4 3.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CpXC PF14353.6 ORY30304.1 - 1.5 8.8 11.0 4.1 7.5 0.1 3.9 2 2 2 4 4 4 0 CpXC protein zf-C2H2_aberr PF17017.5 ORY30304.1 - 1.9 8.6 13.7 12 6.0 3.4 3.8 2 2 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_9 PF16293.5 ORY30304.1 - 8.1 6.4 6.4 14 5.6 0.1 3.6 5 0 0 5 5 4 0 C2H2 type zinc-finger (1 copy) zf-Di19 PF05605.12 ORY30304.1 - 8.8 6.7 24.3 7.3 7.0 3.2 4.4 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 ORY30305.1 - 1e-14 54.1 9.5 3.7e-05 24.0 0.1 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORY30305.1 - 4.7e-10 39.4 18.2 0.0013 19.0 0.2 5.0 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY30305.1 - 1.6e-07 31.6 14.3 0.089 13.7 0.1 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY30305.1 - 0.00052 19.9 8.0 3.4 7.8 0.0 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY30305.1 - 0.00057 20.1 0.5 0.22 11.9 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ORY30305.1 - 0.0019 18.8 2.5 2.7 8.7 0.1 3.7 2 1 1 3 3 3 1 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORY30305.1 - 0.032 14.5 2.8 0.22 11.8 0.3 2.5 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-met PF12874.7 ORY30305.1 - 0.062 13.7 1.2 14 6.2 0.4 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 ORY30305.1 - 4.3 7.3 5.5 1.3 9.0 0.3 2.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 ORY30306.1 - 2.9e-14 52.7 7.8 1.2e-08 35.0 2.8 4.7 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORY30306.1 - 4.1e-13 49.0 21.0 0.00039 20.7 1.2 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY30306.1 - 1.6e-09 37.7 20.0 0.0009 19.9 0.5 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY30306.1 - 4.1e-06 26.9 6.5 0.068 13.5 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORY30306.1 - 0.013 15.7 6.8 0.11 12.8 1.1 2.5 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 ORY30306.1 - 0.039 14.0 11.2 1 9.4 0.1 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 ORY30306.1 - 0.042 14.2 8.2 6.4 7.3 0.2 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 ORY30306.1 - 0.14 12.0 8.9 1.2 8.9 1.6 4.0 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 ORY30307.1 - 4.9e-13 48.8 20.0 0.0049 17.2 1.0 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY30307.1 - 8.7e-13 48.1 18.2 1.7e-05 25.0 0.3 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY30307.1 - 6.3e-10 39.0 18.2 0.003 18.3 0.5 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger FOXP-CC PF16159.5 ORY30307.1 - 0.0035 17.9 10.8 3 8.5 0.4 3.4 2 1 1 3 3 3 3 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 ORY30307.1 - 0.037 14.3 9.4 1.2 9.5 0.2 3.7 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY30307.1 - 0.088 12.8 17.8 0.14 12.2 1.4 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2HE PF16278.5 ORY30307.1 - 0.27 11.7 10.4 27 5.3 4.3 3.6 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DUF3268 PF11672.8 ORY30307.1 - 0.71 10.2 6.2 0.52 10.7 3.8 1.9 1 1 1 2 2 2 0 zinc-finger-containing domain C1_4 PF07975.12 ORY30307.1 - 1.4 9.2 5.7 3.6 7.9 0.4 2.7 1 1 1 2 2 2 0 TFIIH C1-like domain zf_C2H2_ZHX PF18387.1 ORY30307.1 - 4.1 7.1 10.6 0.34 10.6 0.2 3.3 1 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-H2C2_2 PF13465.6 ORY30308.1 - 3.8e-15 55.5 17.0 2.6e-08 33.9 0.1 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORY30308.1 - 3.2e-14 52.5 18.9 0.0004 20.7 0.5 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY30308.1 - 3.4e-09 36.8 17.6 0.0035 18.1 0.4 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY30308.1 - 0.00011 22.4 4.1 0.0027 18.0 0.1 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 ORY30308.1 - 0.0036 17.0 14.8 0.0054 16.5 2.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc-finger domain FOXP-CC PF16159.5 ORY30308.1 - 0.0067 17.0 5.7 0.36 11.5 0.1 3.4 2 1 1 3 3 3 1 FOXP coiled-coil domain zf-met PF12874.7 ORY30308.1 - 0.018 15.4 0.2 0.018 15.4 0.2 3.7 4 0 0 4 4 3 0 Zinc-finger of C2H2 type TRAF6_Z2 PF18048.1 ORY30308.1 - 0.067 13.3 4.8 4.4 7.5 0.1 3.6 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_8 PF15909.5 ORY30308.1 - 0.37 11.1 5.0 0.18 12.1 0.9 2.3 1 1 0 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 ORY30308.1 - 0.51 10.4 6.0 6.2 6.9 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORY30308.1 - 0.82 9.8 4.6 16 5.6 2.8 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2 PF00096.26 ORY30309.1 - 9e-16 57.4 20.5 0.00011 22.5 1.0 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY30309.1 - 1.1e-14 54.0 27.6 4.3e-08 33.2 0.3 5.3 5 1 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY30309.1 - 1.1e-13 50.7 20.3 0.0019 18.8 0.7 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY30309.1 - 1.3e-10 41.3 8.6 0.0009 19.5 0.1 3.8 3 1 1 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY30309.1 - 9.5e-08 31.9 11.1 0.0066 16.4 0.4 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORY30309.1 - 5.8e-05 22.8 3.6 0.0093 15.7 0.0 3.7 4 0 0 4 4 4 1 zinc-finger C2H2-type zf-met PF12874.7 ORY30309.1 - 0.0013 19.0 9.6 0.67 10.4 0.7 3.6 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 ORY30309.1 - 0.0015 18.2 11.4 0.19 11.4 0.1 3.4 1 1 2 3 3 3 2 Zinc-fingers and homeoboxes C2H2 finger domain FOXP-CC PF16159.5 ORY30309.1 - 0.0048 17.5 9.3 0.3 11.7 0.0 3.6 1 1 2 4 4 4 1 FOXP coiled-coil domain TRAF6_Z2 PF18048.1 ORY30309.1 - 0.012 15.7 4.3 0.58 10.3 0.0 3.8 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 zf_UBZ PF18439.1 ORY30309.1 - 0.018 14.6 1.4 1.5 8.5 0.2 2.8 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-LYAR PF08790.11 ORY30309.1 - 0.032 14.1 2.1 2.9 7.9 0.0 3.3 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 ORY30309.1 - 0.066 13.6 12.7 8.2 6.8 0.1 3.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_aberr PF17017.5 ORY30309.1 - 0.35 11.0 8.3 4.8 7.3 2.9 2.4 2 1 1 3 3 3 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 ORY30309.1 - 0.79 9.5 24.8 0.13 12.0 2.2 4.9 4 1 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2HE PF16278.5 ORY30309.1 - 1.2 9.7 14.7 2.2 8.8 0.6 3.3 2 2 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-BED PF02892.15 ORY30309.1 - 3.7 7.6 13.8 1.2 9.2 0.3 3.6 1 1 2 3 3 3 0 BED zinc finger zf-C2H2 PF00096.26 ORY30310.1 - 1e-12 47.7 20.5 0.0068 16.8 1.3 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY30310.1 - 1.4e-12 47.4 12.1 9.4e-05 22.7 0.4 4.7 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY30310.1 - 6.6e-10 39.0 19.6 0.0087 16.8 1.1 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY30310.1 - 0.0011 18.9 14.8 1.9 8.6 0.3 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger FOXP-CC PF16159.5 ORY30310.1 - 0.002 18.7 7.0 0.19 12.4 0.3 3.4 2 1 1 3 3 3 1 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 ORY30310.1 - 0.0046 16.7 4.0 0.036 13.8 0.1 3.0 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 ORY30310.1 - 0.021 15.1 3.2 0.021 15.1 3.2 2.8 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 ORY30310.1 - 0.034 14.4 10.4 1.4 9.3 0.1 3.8 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 ORY30310.1 - 0.2 11.6 9.3 0.38 10.7 0.2 3.2 3 1 0 3 3 2 0 zinc-finger of a C2HC-type Med27 PF11571.8 ORY30310.1 - 0.2 12.1 5.5 9.6 6.7 0.4 3.4 3 0 0 3 3 3 0 Mediator complex subunit 27 zf-met PF12874.7 ORY30310.1 - 4.6 7.8 10.2 11 6.6 0.3 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zinc_ribbon_15 PF17032.5 ORY30310.1 - 4.7 8.0 8.4 42 5.0 0.2 3.3 2 1 2 4 4 4 0 zinc-ribbon family GSIII_N PF12437.8 ORY30311.1 - 2.7e-61 205.9 0.0 4.1e-61 205.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 ORY30311.1 - 3e-39 133.5 0.0 5.7e-39 132.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 ORY30311.1 - 5.2e-21 75.0 0.0 1.3e-20 73.7 0.0 1.6 2 0 0 2 2 2 1 Glutamine synthetase, catalytic domain zf-C2H2 PF00096.26 ORY30313.1 - 1e-17 63.5 30.5 0.00042 20.6 0.7 5.5 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY30313.1 - 7.1e-17 61.0 21.6 6.1e-08 32.8 1.3 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY30313.1 - 2.9e-15 55.7 26.3 0.00083 20.0 1.4 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger FOXP-CC PF16159.5 ORY30313.1 - 7.5e-06 26.5 2.6 3.2 8.5 0.1 4.2 3 1 1 4 4 4 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 ORY30313.1 - 0.00049 20.3 9.8 0.19 12.0 0.0 5.0 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 ORY30313.1 - 0.0039 17.4 8.5 0.71 10.0 0.0 3.9 2 1 0 4 4 4 2 Aberrant zinc-finger zf-TRAF PF02176.18 ORY30313.1 - 0.0086 16.8 10.7 0.47 11.2 1.8 2.9 3 0 0 3 3 3 2 TRAF-type zinc finger Spt46 PF17734.1 ORY30313.1 - 0.061 13.1 2.7 4 7.2 0.4 2.2 1 1 1 2 2 2 0 Spermatogenesis-associated protein 46 DUF3268 PF11672.8 ORY30313.1 - 0.31 11.4 4.4 6.8 7.1 0.4 2.3 2 0 0 2 2 2 0 zinc-finger-containing domain zf-met PF12874.7 ORY30313.1 - 0.47 10.9 14.8 0.82 10.2 0.5 5.1 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 ORY30313.1 - 2 8.3 15.7 1.6 8.6 0.4 4.5 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 ORY30313.1 - 2.6 7.9 8.5 11 5.9 0.3 3.7 4 0 0 4 4 4 0 zinc-finger C2H2-type RNase_P_pop3 PF08228.11 ORY30314.1 - 3.2e-13 50.0 0.0 9.9e-13 48.4 0.0 1.7 2 0 0 2 2 2 1 RNase P subunit Pop3 Ribosomal_L7Ae PF01248.26 ORY30314.1 - 7e-06 25.7 0.0 1.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family NPBW PF15180.6 ORY30314.1 - 0.21 11.5 1.6 4.1 7.3 0.1 2.4 1 1 1 2 2 2 0 Neuropeptides B and W Ammonium_transp PF00909.21 ORY30315.1 - 2.5e-106 355.8 33.8 2.8e-106 355.6 33.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family SR-25 PF10500.9 ORY30316.1 - 3e-27 95.7 37.8 4.1e-22 78.9 1.1 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein SOBP PF15279.6 ORY30316.1 - 0.037 14.6 16.9 0.045 14.4 16.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CDC45 PF02724.14 ORY30316.1 - 0.18 10.1 12.8 0.2 9.9 12.8 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 ORY30316.1 - 0.19 11.8 20.7 0.24 11.5 20.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Apt1 PF10351.9 ORY30316.1 - 0.4 9.5 13.1 0.43 9.4 13.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Dsh_C PF12316.8 ORY30316.1 - 1.1 9.6 21.4 1.6 9.1 21.4 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Peptidase_S64 PF08192.11 ORY30316.1 - 1.5 7.2 9.5 1.3 7.5 9.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 Macoilin PF09726.9 ORY30316.1 - 2.7 6.5 12.9 2.8 6.4 12.9 1.1 1 0 0 1 1 1 0 Macoilin family SLC12 PF03522.15 ORY30316.1 - 3 6.8 9.9 3.1 6.7 9.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 cNMP_binding PF00027.29 ORY30317.1 - 1.2e-20 73.4 0.0 2.7e-18 65.8 0.0 2.6 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain cNMP_binding PF00027.29 ORY30318.1 - 7.4e-37 125.3 0.0 2.7e-18 65.8 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Ion_trans PF00520.31 ORY30318.1 - 1.5e-06 27.6 14.1 2.5e-06 26.9 14.1 1.2 1 0 0 1 1 1 1 Ion transport protein Glu-tRNAGln PF02686.15 ORY30318.1 - 0.16 12.3 0.4 9.9 6.5 0.0 2.9 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit Utp12 PF04003.12 ORY30320.1 - 6.3e-24 84.3 2.3 6.3e-24 84.3 2.3 1.7 2 0 0 2 2 2 1 Dip2/Utp12 Family Hira PF07569.11 ORY30320.1 - 0.006 16.3 1.8 0.052 13.3 0.6 2.7 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 ORY30320.1 - 0.14 13.1 4.6 0.7 10.9 0.1 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat PQ-loop PF04193.14 ORY30321.1 - 8.5e-09 35.1 0.6 1.3e-08 34.5 0.2 1.5 1 1 0 1 1 1 1 PQ loop repeat MtN3_slv PF03083.16 ORY30321.1 - 0.04 13.9 0.8 0.073 13.1 0.8 1.4 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange Phtf-FEM1B_bdg PF12129.8 ORY30321.1 - 0.083 12.7 0.4 0.43 10.4 0.1 1.9 1 1 1 2 2 2 0 Male germ-cell putative homeodomain transcription factor DDE_Tnp_4 PF13359.6 ORY30322.1 - 3.1e-15 56.2 0.0 4.5e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.14 ORY30322.1 - 0.00026 20.6 0.0 0.00041 20.0 0.0 1.2 1 0 0 1 1 1 1 Plant transposon protein DUF4274 PF14096.6 ORY30322.1 - 0.074 13.0 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4274) DCA16 PF15349.6 ORY30323.1 - 0.087 12.4 0.1 0.087 12.4 0.1 2.0 2 0 0 2 2 2 0 DDB1- and CUL4-associated factor 16 TFIIA PF03153.13 ORY30323.1 - 0.25 11.3 16.4 0.012 15.6 4.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2456 PF10445.9 ORY30439.1 - 0.12 12.4 5.4 0.17 12.0 0.8 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2456) PH_17 PF18012.1 ORY30440.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 PH domain Na_Ca_ex PF01699.24 ORY30442.1 - 8.6e-32 110.2 25.0 7.9e-25 87.6 13.1 2.8 2 1 0 2 2 2 2 Sodium/calcium exchanger protein Na_Ca_ex PF01699.24 ORY30444.1 - 3e-15 56.5 21.8 2.3e-13 50.3 7.9 3.2 2 1 0 2 2 2 2 Sodium/calcium exchanger protein PilX_N PF14341.6 ORY30444.1 - 0.83 9.7 9.2 0.079 12.9 4.0 2.1 2 0 0 2 2 2 0 PilX N-terminal CH_2 PF06294.11 ORY30447.1 - 2.6e-13 49.9 0.3 2.4e-11 43.6 0.0 3.2 3 0 0 3 3 3 1 CH-like domain in sperm protein Hydin_ADK PF17213.3 ORY30447.1 - 0.0014 18.9 0.0 0.0014 18.9 0.0 3.4 3 1 0 3 3 3 1 Hydin Adenylate kinase-like domain V-ATPase_H_N PF03224.14 ORY30448.1 - 4.7e-62 210.1 4.1 2.8e-53 181.3 1.2 2.1 2 0 0 2 2 2 2 V-ATPase subunit H V-ATPase_H_C PF11698.8 ORY30448.1 - 2.2e-25 89.0 1.2 3.4e-22 78.8 0.0 3.9 2 2 2 4 4 4 2 V-ATPase subunit H RTP1_C1 PF10363.9 ORY30448.1 - 0.019 15.1 0.1 0.27 11.4 0.0 2.7 2 2 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 ORY30448.1 - 0.046 13.8 2.0 0.24 11.5 0.8 2.6 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 TAN PF11640.8 ORY30448.1 - 0.082 13.0 0.1 0.25 11.5 0.1 1.8 1 1 0 1 1 1 0 Telomere-length maintenance and DNA damage repair Coa1 PF08695.10 ORY30449.1 - 1.2e-15 57.3 0.0 1.5e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Nuf2 PF03800.14 ORY30450.1 - 2.9e-42 144.1 0.4 2.9e-42 144.1 0.4 2.9 2 1 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 ORY30450.1 - 8.7e-25 87.1 24.0 8.7e-25 87.1 24.0 3.2 2 1 0 3 3 3 1 Designed helical repeat protein 10 domain UPF0242 PF06785.11 ORY30450.1 - 0.1 12.7 41.7 0.064 13.4 15.1 3.1 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Occludin_ELL PF07303.13 ORY30450.1 - 4.3 8.1 28.2 0.2 12.4 5.3 3.5 1 1 1 3 3 3 0 Occludin homology domain DUF3584 PF12128.8 ORY30450.1 - 8.3 3.8 38.8 3.2 5.1 10.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) BBS2_C PF14782.6 ORY30451.1 - 1.3e-11 44.0 0.2 6.5e-05 21.9 0.3 3.1 2 1 1 3 3 3 3 Ciliary BBSome complex subunit 2, C-terminal DUF2958 PF11171.8 ORY30451.1 - 0.022 15.0 0.0 0.047 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2958) DUF1848 PF08902.11 ORY30452.1 - 0.047 13.4 0.3 0.93 9.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) TPR_MLP1_2 PF07926.12 ORY30452.1 - 0.098 12.7 0.6 1.4 8.9 0.1 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4851 PF16143.5 ORY30452.1 - 0.11 12.0 0.0 0.43 10.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4851) MscS_porin PF12795.7 ORY30452.1 - 0.33 10.5 2.2 0.95 9.0 0.2 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Arf PF00025.21 ORY30453.1 - 9e-43 145.7 0.0 1e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 ORY30453.1 - 7.3e-15 54.9 0.0 8.7e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY30453.1 - 8.5e-15 55.0 0.0 1.2e-14 54.5 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 ORY30453.1 - 1.1e-10 41.2 0.1 2.7e-07 30.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 ORY30453.1 - 2.6e-10 40.4 0.0 3.4e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 ORY30453.1 - 2.6e-09 36.8 0.0 3.3e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORY30453.1 - 9.5e-07 28.4 0.0 1.1e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORY30453.1 - 4.1e-06 26.5 0.1 0.0039 16.8 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 ORY30453.1 - 0.0019 18.5 0.1 0.0065 16.7 0.0 1.9 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.18 ORY30453.1 - 0.0029 17.2 0.1 0.0074 15.8 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 ORY30453.1 - 0.0072 16.1 0.0 0.62 9.8 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein NOG1 PF06858.14 ORY30453.1 - 0.018 14.8 0.0 0.047 13.5 0.0 1.7 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) KAP_NTPase PF07693.14 ORY30453.1 - 0.065 12.5 0.0 0.95 8.6 0.0 2.0 2 0 0 2 2 2 0 KAP family P-loop domain ATPase_2 PF01637.18 ORY30453.1 - 0.08 12.8 0.0 0.57 10.1 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea cobW PF02492.19 ORY30453.1 - 0.085 12.4 0.1 13 5.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Thymidylate_kin PF02223.17 ORY30453.1 - 0.085 12.5 0.1 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Thymidylate kinase MeaB PF03308.16 ORY30453.1 - 0.11 11.5 0.0 0.76 8.7 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 ORY30453.1 - 0.12 12.5 0.0 8.6 6.4 0.0 2.2 1 1 1 2 2 2 0 Dynamin family Mic1 PF07035.12 ORY30454.1 - 0.00015 21.5 0.2 0.00023 20.9 0.2 1.3 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like DUF776 PF05604.11 ORY30454.1 - 0.12 12.7 0.8 0.16 12.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF776) RIIa PF02197.17 ORY30456.1 - 2.5e-05 23.8 0.0 4.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit DUF4476 PF14771.6 ORY30456.1 - 0.012 15.9 0.0 0.037 14.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) Ribosomal_L22 PF00237.19 ORY30457.1 - 5.4e-43 145.4 0.1 8.7e-43 144.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Asp_Glu_race_2 PF14669.6 ORY30457.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative aspartate racemase TSNAXIP1_N PF15739.5 ORY30458.1 - 7.6e-21 74.6 0.0 7.6e-21 74.6 0.0 3.0 3 1 0 3 3 3 1 Translin-associated factor X-interacting N-terminus DUF4041 PF13250.6 ORY30458.1 - 0.012 15.5 0.1 0.041 13.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) GMP_PDE_delta PF05351.11 ORY30459.1 - 3.5e-44 150.6 7.7 4.3e-43 147.1 7.7 2.0 1 1 0 1 1 1 1 GMP-PDE, delta subunit PPTA PF01239.22 ORY30460.1 - 5.8e-29 98.9 18.5 9.7e-09 34.7 0.6 6.2 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF4219 PF13961.6 ORY30460.1 - 0.22 11.2 9.3 8.1 6.2 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) Pkinase PF00069.25 ORY30461.1 - 8.4e-76 254.8 0.0 9.5e-76 254.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY30461.1 - 7.1e-35 120.5 0.0 8.9e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY30461.1 - 4e-05 22.7 0.1 0.00029 19.9 0.1 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY30461.1 - 0.045 13.1 0.2 0.096 12.0 0.2 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY30461.1 - 0.047 13.0 0.1 0.44 9.8 0.0 2.1 1 1 1 2 2 2 0 Kinase-like FUSC PF04632.12 ORY30462.1 - 9.8 4.6 10.9 1.6 7.1 2.0 2.3 2 0 0 2 2 2 0 Fusaric acid resistance protein family Nucleoporin_FG PF13634.6 ORY30463.1 - 0.014 16.2 88.4 0.79 10.6 17.5 4.4 2 1 2 4 4 4 0 Nucleoporin FG repeat region zf-RanBP PF00641.18 ORY30464.1 - 0.00024 20.3 4.3 0.00058 19.1 4.3 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others CENP-Q PF13094.6 ORY30464.1 - 0.02 15.1 0.9 0.02 15.1 0.9 2.2 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit FapA PF03961.13 ORY30464.1 - 0.19 10.3 2.5 0.25 9.9 2.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A YdiH PF15930.5 ORY30464.1 - 0.27 11.4 0.8 0.53 10.5 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function SHE3 PF17078.5 ORY30464.1 - 0.68 9.6 4.9 0.58 9.8 3.0 1.7 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Pro_isomerase PF00160.21 ORY30465.1 - 6.2e-48 163.1 0.4 7.1e-48 162.9 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LRR_8 PF13855.6 ORY30466.1 - 5.3e-16 58.1 36.0 2.9e-07 30.1 1.2 3.6 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY30466.1 - 1.3e-15 57.2 9.0 2.5e-06 27.7 2.0 3.6 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY30466.1 - 3e-09 36.1 19.1 0.12 13.0 0.2 6.6 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_6 PF13516.6 ORY30466.1 - 4.8e-06 26.2 12.2 0.6 10.3 0.0 4.7 4 0 0 4 4 4 4 Leucine Rich repeat MFS_1 PF07690.16 ORY30467.1 - 7.7e-24 84.3 29.8 7.7e-24 84.3 29.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2681 PF10883.8 ORY30467.1 - 0.78 10.2 2.5 0.67 10.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF2417 PF10329.9 ORY30467.1 - 5.4 6.4 7.8 0.21 10.9 0.1 2.6 4 0 0 4 4 4 0 Region of unknown function (DUF2417) RICTOR_N PF14664.6 ORY30470.1 - 2.6e-76 257.0 2.9 2.6e-76 257.0 2.9 1.7 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 ORY30470.1 - 2e-28 98.2 3.5 1.4e-24 85.9 0.2 4.8 3 1 1 4 4 4 2 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 ORY30470.1 - 2.4e-25 88.5 5.4 2.1e-23 82.4 0.4 4.5 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N_2 PF14663.6 ORY30470.1 - 9.6e-21 74.2 0.3 1.6e-18 67.1 0.0 3.0 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain Pterin_bind PF00809.22 ORY30471.1 - 6.7e-85 284.6 0.2 1e-84 284.1 0.2 1.3 1 0 0 1 1 1 1 Pterin binding enzyme FolB PF02152.18 ORY30471.1 - 4.2e-49 165.7 1.0 3.8e-23 82.2 0.0 2.6 3 0 0 3 3 3 2 Dihydroneopterin aldolase HPPK PF01288.20 ORY30471.1 - 1.8e-36 125.0 0.0 4e-36 123.9 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) PEP_mutase PF13714.6 ORY30471.1 - 0.12 11.8 0.5 9.7 5.6 0.0 2.4 1 1 1 2 2 2 0 Phosphoenolpyruvate phosphomutase Clathrin PF00637.20 ORY30472.1 - 6.4e-11 42.3 28.5 0.091 12.6 0.1 10.6 7 3 6 13 13 12 3 Region in Clathrin and VPS WD40 PF00400.32 ORY30472.1 - 8.1e-10 39.1 2.8 3.4 8.7 0.0 7.0 7 0 0 7 7 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY30472.1 - 6e-09 36.1 0.1 1.4 9.3 0.0 5.3 3 2 3 6 6 5 4 Anaphase-promoting complex subunit 4 WD40 domain PPR PF01535.20 ORY30472.1 - 4.8e-07 29.6 17.1 1.1 9.6 0.0 8.9 10 0 0 10 10 10 3 PPR repeat Coatomer_WDAD PF04053.14 ORY30472.1 - 4.1e-06 26.1 17.5 0.0085 15.2 1.1 6.4 5 2 1 6 6 6 2 Coatomer WD associated region TPR_7 PF13176.6 ORY30472.1 - 0.00043 20.1 10.5 13 6.1 0.0 8.7 8 1 0 8 8 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY30472.1 - 0.001 19.3 18.8 0.12 12.6 0.2 8.3 8 2 0 8 8 8 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 ORY30472.1 - 0.0045 17.7 11.7 72 4.6 0.0 9.3 10 0 0 10 10 8 0 Tetratricopeptide repeat Ge1_WD40 PF16529.5 ORY30472.1 - 0.035 13.1 0.1 2.8 6.8 0.0 2.9 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_12 PF13424.6 ORY30472.1 - 0.04 14.2 19.5 3.8 7.9 0.2 8.8 9 1 0 9 9 8 0 Tetratricopeptide repeat Sec16_C PF12931.7 ORY30472.1 - 0.1 12.2 4.2 4.3 6.9 0.3 3.5 3 1 1 4 4 4 0 Sec23-binding domain of Sec16 PPR_2 PF13041.6 ORY30472.1 - 0.16 12.2 11.8 3.4 7.9 0.2 6.0 6 0 0 6 6 4 0 PPR repeat family TPR_2 PF07719.17 ORY30472.1 - 0.23 11.7 27.1 4.5 7.6 0.0 11.3 12 3 3 15 15 15 0 Tetratricopeptide repeat PPR_1 PF12854.7 ORY30472.1 - 0.48 10.2 3.0 41 4.0 0.0 4.5 4 0 0 4 4 4 0 PPR repeat TPR_19 PF14559.6 ORY30472.1 - 0.48 11.0 12.1 15 6.1 0.0 7.2 8 2 0 8 8 6 0 Tetratricopeptide repeat DUF410 PF04190.13 ORY30472.1 - 0.55 10.0 13.1 0.67 9.7 0.1 4.2 1 1 0 4 4 4 0 Protein of unknown function (DUF410) TPR_6 PF13174.6 ORY30472.1 - 3.4 8.5 4.9 3.7e+02 2.1 0.0 6.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY30472.1 - 5.2 7.1 28.1 3.2 7.7 0.0 9.6 10 2 2 12 12 11 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY30472.1 - 5.3 7.5 18.4 44 4.6 0.1 8.5 9 0 0 9 9 9 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 ORY30472.1 - 7.7 6.5 10.5 31 4.6 0.3 5.8 7 0 0 7 7 7 0 Mad3/BUB1 homology region 1 Aldose_epim PF01263.20 ORY30473.1 - 9.7e-45 153.1 0.4 1.1e-44 153.0 0.4 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Meth_synt_2 PF01717.18 ORY30474.1 - 1.5e-149 497.7 0.0 1.1e-146 488.2 0.0 2.5 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 ORY30474.1 - 2.4e-110 368.9 0.0 1.8e-102 343.1 0.0 2.5 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain DUF1768 PF08719.11 ORY30475.1 - 1.1e-26 94.1 0.0 2e-26 93.1 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1768) TPR_2 PF07719.17 ORY30476.1 - 0.00035 20.5 5.6 0.021 14.9 0.1 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY30476.1 - 0.0005 19.7 1.8 0.066 12.9 0.1 3.2 3 0 0 3 3 3 1 TPR repeat STAS PF01740.21 ORY30476.1 - 0.0011 18.5 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 STAS domain TPR_17 PF13431.6 ORY30476.1 - 0.0013 19.0 0.7 0.0067 16.7 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY30476.1 - 0.0035 17.9 3.3 0.48 11.2 1.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY30476.1 - 0.018 15.3 0.6 2.5 8.4 0.0 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY30476.1 - 0.028 14.4 0.2 0.74 10.0 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY30476.1 - 0.12 12.3 5.2 9.3 6.3 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Spore_III_AB PF09548.10 ORY30476.1 - 0.25 11.5 6.2 1.3 9.1 1.7 2.6 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Holin_BhlA PF10960.8 ORY30477.1 - 6.7 6.8 15.9 3.3 7.8 1.4 4.2 2 1 1 3 3 3 0 BhlA holin family KDZ PF18758.1 ORY30478.1 - 1.5e-06 28.0 0.2 2.2e-06 27.5 0.2 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC4 PF18717.1 ORY30480.1 - 6.7e-30 103.6 1.3 1.5e-29 102.5 0.5 1.7 2 0 0 2 2 2 1 CxC4 like cysteine cluster associated with KDZ transposases zf-RING_4 PF14570.6 ORY30480.1 - 0.0024 17.6 1.5 0.31 10.9 0.0 3.0 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-C2H2_3 PF13878.6 ORY30480.1 - 0.045 13.6 3.7 2.6 7.9 0.1 3.2 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO CxC5 PF18718.1 ORY30480.1 - 0.12 12.4 2.5 0.15 12.1 0.3 2.1 2 0 0 2 2 2 0 CxC5 like cysteine cluster associated with KDZ transposases zf-TFIIB PF13453.6 ORY30480.1 - 0.49 9.8 3.1 3.3 7.1 0.0 2.7 3 0 0 3 3 3 0 Transcription factor zinc-finger Zn-ribbon_8 PF09723.10 ORY30480.1 - 2.2 8.5 9.8 7.8 6.7 0.1 2.7 2 1 0 2 2 2 0 Zinc ribbon domain DUF35_N PF12172.8 ORY30480.1 - 3.6 7.5 7.2 46 4.0 0.2 3.2 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF4746 PF15928.5 ORY30481.1 - 0.037 13.4 0.4 0.059 12.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Trypan_PARP PF05887.11 ORY30481.1 - 0.054 13.5 5.5 0.093 12.7 5.5 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Eapp_C PF10238.9 ORY30481.1 - 0.14 12.2 7.8 0.14 12.3 6.3 1.7 2 0 0 2 2 2 0 E2F-associated phosphoprotein DNA_pol_phi PF04931.13 ORY30481.1 - 0.25 9.4 7.8 0.3 9.1 7.1 1.4 2 0 0 2 2 2 0 DNA polymerase phi CENP-B_dimeris PF09026.10 ORY30481.1 - 0.3 11.5 3.0 0.73 10.3 3.0 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain MAP17 PF15807.5 ORY30481.1 - 6.8 6.9 6.7 12 6.1 6.7 1.4 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Atrophin-1 PF03154.15 ORY30481.1 - 9.7 4.3 5.8 15 3.7 5.8 1.2 1 0 0 1 1 1 0 Atrophin-1 family HD_4 PF13328.6 ORY30482.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.4 1 1 0 1 1 1 0 HD domain Choline_transpo PF04515.12 ORY30483.1 - 2.5e-85 286.5 40.5 2.5e-85 286.5 40.5 2.7 2 1 1 3 3 3 1 Plasma-membrane choline transporter Hum_adeno_E3A PF05393.11 ORY30483.1 - 0.01 15.8 0.4 0.01 15.8 0.4 2.6 3 0 0 3 3 3 0 Human adenovirus early E3A glycoprotein DUF948 PF06103.11 ORY30483.1 - 1.8 8.9 4.0 2.8 8.2 0.4 2.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TFCD_C PF12612.8 ORY30484.1 - 1.4e-40 139.2 1.1 2.7e-40 138.2 0.4 2.0 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 ORY30484.1 - 2.2e-05 24.8 6.5 1.3 9.4 0.0 6.0 7 2 0 7 7 7 2 HEAT repeats HEAT PF02985.22 ORY30484.1 - 0.00014 21.8 10.2 0.27 11.6 0.0 7.2 9 0 0 9 9 9 1 HEAT repeat Vac14_Fab1_bd PF12755.7 ORY30484.1 - 0.0012 19.4 0.6 4.4 8.0 0.0 4.4 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 ORY30484.1 - 0.0046 17.4 2.5 27 5.4 0.0 5.9 5 1 1 6 6 6 1 HEAT-like repeat LRR_8 PF13855.6 ORY30485.1 - 1e-05 25.2 8.5 2.4e-05 24.0 0.7 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY30485.1 - 0.00051 20.4 0.4 0.00051 20.4 0.4 2.5 2 1 0 2 2 2 1 Leucine Rich repeats (2 copies) CDC45 PF02724.14 ORY30485.1 - 0.0055 15.1 8.3 0.0078 14.6 8.3 1.3 1 0 0 1 1 1 1 CDC45-like protein LRR_1 PF00560.33 ORY30485.1 - 0.78 10.5 0.1 0.78 10.5 0.1 3.3 3 1 0 3 3 3 0 Leucine Rich Repeat DNA_pol_phi PF04931.13 ORY30485.1 - 7.1 4.6 19.0 11 4.0 19.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi MRP-L47 PF06984.13 ORY30486.1 - 1.7e-19 69.7 0.1 2.4e-19 69.3 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.12 ORY30486.1 - 0.17 11.3 0.1 0.25 10.8 0.1 1.2 1 0 0 1 1 1 0 Clc-like NHL PF01436.21 ORY30487.1 - 0.091 12.8 2.0 12 6.2 0.0 3.8 3 0 0 3 3 3 0 NHL repeat DUF1674 PF07896.12 ORY30488.1 - 2.3e-21 76.0 5.2 8.3e-21 74.2 5.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) CagY_I PF14585.6 ORY30488.1 - 0.12 12.5 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 CagY type 1 repeat FRG1 PF06229.12 ORY30489.1 - 2.1e-28 99.3 3.6 7.5e-14 51.9 0.0 2.1 2 0 0 2 2 2 2 FRG1-like domain Fascin PF06268.13 ORY30489.1 - 1.4e-05 25.3 0.0 0.00013 22.1 0.0 2.3 2 1 1 3 3 3 1 Fascin domain Mannosyl_trans3 PF11051.8 ORY30490.1 - 1e-40 139.8 0.0 2.2e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative Dynactin_p62 PF05502.13 ORY30490.1 - 4.2 6.0 8.0 7 5.3 8.0 1.3 1 0 0 1 1 1 0 Dynactin p62 family SlyX PF04102.12 ORY30491.1 - 0.025 15.2 18.4 0.73 10.5 0.2 4.2 2 1 1 4 4 4 0 SlyX PNPase PF03726.14 ORY30491.1 - 0.066 13.7 3.0 0.17 12.4 3.0 1.8 1 1 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain ATAD4 PF15321.6 ORY30491.1 - 0.081 14.3 5.3 0.095 14.1 0.1 2.7 2 1 0 2 2 2 0 ATPase family AAA domain containing 4 DUF2935 PF11155.8 ORY30491.1 - 0.11 12.8 0.8 0.19 12.0 0.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) XhlA PF10779.9 ORY30491.1 - 0.27 11.5 2.4 4.9 7.4 0.0 3.0 3 0 0 3 3 3 0 Haemolysin XhlA FAM76 PF16046.5 ORY30491.1 - 1.3 8.3 13.4 2.5 7.3 5.0 2.2 2 0 0 2 2 2 0 FAM76 protein XLF PF09302.11 ORY30491.1 - 1.5 8.9 7.3 11 6.1 0.8 3.0 2 1 1 3 3 3 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component MEKHLA PF08670.11 ORY30493.1 - 5.4e-28 97.7 0.0 6.8e-28 97.4 0.0 1.0 1 0 0 1 1 1 1 MEKHLA domain PAS_4 PF08448.10 ORY30493.1 - 0.0017 18.6 0.0 0.0024 18.1 0.0 1.2 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 ORY30493.1 - 0.011 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 PAS domain Peptidase_M48_N PF16491.5 ORY30494.1 - 1.9e-56 190.9 0.6 1.9e-56 190.9 0.6 1.7 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 ORY30494.1 - 1.3e-38 132.8 0.0 2.3e-38 132.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 ORY30494.1 - 5.2e-05 22.6 0.2 7.2e-05 22.1 0.2 1.3 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF2268 PF10026.9 ORY30494.1 - 0.062 12.9 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) SprT-like PF10263.9 ORY30494.1 - 0.066 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 SprT-like family DUF3684 PF12449.8 ORY30496.1 - 1.3e-279 930.6 0.9 5.6e-272 905.3 0.2 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3684) CUE PF02845.16 ORY30496.1 - 0.0067 16.1 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 CUE domain Reprolysin_5 PF13688.6 ORY30496.1 - 0.15 12.2 1.0 0.39 10.8 0.1 2.2 2 0 0 2 2 2 0 Metallo-peptidase family M12 WLM PF08325.10 ORY30496.1 - 1.5 8.8 5.5 0.24 11.4 0.5 2.1 2 0 0 2 2 2 0 WLM domain Plasmodium_Vir PF05795.11 ORY30496.1 - 2.5 7.4 4.1 4.5 6.6 4.1 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Glyco_transf_43 PF03360.16 ORY30497.1 - 2.1e-05 24.5 0.0 2.4e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 43 Epimerase PF01370.21 ORY30498.1 - 2.5e-48 164.7 0.0 3.2e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY30498.1 - 1.6e-43 149.4 0.0 1.6e-42 146.1 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ORY30498.1 - 3e-25 88.8 0.0 4.5e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ORY30498.1 - 5.8e-16 58.5 0.0 3.6e-15 55.9 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 ORY30498.1 - 5.8e-11 42.0 0.4 2.7e-08 33.3 0.4 2.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 ORY30498.1 - 1.1e-08 35.2 0.0 1.9e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ORY30498.1 - 4.4e-08 32.6 0.0 7.7e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 ORY30498.1 - 0.0013 18.3 0.0 0.003 17.0 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 ORY30498.1 - 0.0031 17.1 0.0 0.021 14.4 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family MEKHLA PF08670.11 ORY30499.1 - 0.00013 21.9 0.1 0.00017 21.5 0.1 1.2 1 0 0 1 1 1 1 MEKHLA domain Thioredoxin_2 PF13098.6 ORY30500.1 - 0.23 11.9 0.9 0.81 10.2 0.1 2.4 2 0 0 2 2 2 0 Thioredoxin-like domain Filament PF00038.21 ORY30500.1 - 1 8.9 87.2 0.0074 15.9 30.1 4.5 1 1 3 4 4 4 0 Intermediate filament protein Spc7 PF08317.11 ORY30500.1 - 4.8 6.0 92.1 0.031 13.2 9.7 6.2 1 1 6 7 7 7 0 Spc7 kinetochore protein Fez1 PF06818.15 ORY30500.1 - 8.3 6.8 77.5 1.7 9.1 13.6 5.3 1 1 3 4 4 4 0 Fez1 DNA_pol3_delta2 PF13177.6 ORY30501.1 - 3.2e-13 49.8 0.2 5.9e-13 48.9 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 ORY30501.1 - 5.8e-08 33.2 0.1 1.5e-07 31.9 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ORY30501.1 - 0.00036 20.5 0.1 0.00075 19.5 0.1 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain ABC_tran PF00005.27 ORY30501.1 - 0.00053 20.5 0.0 0.002 18.7 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 ORY30501.1 - 0.0028 18.1 0.0 0.0099 16.3 0.0 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_assoc_2 PF16193.5 ORY30501.1 - 0.0036 17.6 0.0 0.012 15.9 0.0 1.8 2 0 0 2 2 2 1 AAA C-terminal domain AAA_11 PF13086.6 ORY30501.1 - 0.0056 16.5 2.2 3 7.5 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.6 ORY30501.1 - 0.0089 16.3 0.8 0.044 14.1 0.8 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ORY30501.1 - 0.046 13.7 0.4 0.12 12.4 0.4 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.9 ORY30501.1 - 0.052 12.8 0.2 0.079 12.2 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.13 ORY30501.1 - 0.068 12.3 0.0 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATG22 PF11700.8 ORY30502.1 - 2.4e-68 230.9 16.3 3e-68 230.6 16.3 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 ORY30502.1 - 0.49 9.3 36.1 0.59 9.0 13.8 2.7 1 1 1 2 2 2 0 Major Facilitator Superfamily SIR2 PF02146.17 ORY30503.1 - 1.7e-31 109.5 0.0 1.1e-19 71.0 0.0 2.3 2 0 0 2 2 2 2 Sir2 family DUF3439 PF11921.8 ORY30504.1 - 9.7 6.2 15.6 0.66 10.0 10.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) UvrD-helicase PF00580.21 ORY30505.1 - 1.1e-15 58.0 2.0 4.5e-10 39.6 0.0 2.6 2 1 0 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 ORY30505.1 - 7.6e-14 52.3 0.0 2.2e-13 50.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain UvrD_C PF13361.6 ORY30505.1 - 2.7e-07 30.3 0.0 4.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 ORY30505.1 - 1.5e-05 24.8 0.0 3.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 ORY30505.1 - 0.00023 20.9 0.1 0.28 11.0 0.0 3.1 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain ResIII PF04851.15 ORY30505.1 - 0.0011 18.9 0.4 0.0032 17.5 0.4 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY30505.1 - 0.053 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF853 PF05872.12 ORY30505.1 - 0.086 11.4 0.1 0.14 10.7 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_16 PF13191.6 ORY30505.1 - 0.088 13.2 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_34 PF13872.6 ORY30505.1 - 0.12 11.2 0.0 0.39 9.6 0.0 1.8 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 SRP54 PF00448.22 ORY30505.1 - 0.17 11.5 0.2 0.37 10.4 0.2 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain TFIIA PF03153.13 ORY30505.1 - 3 7.7 12.1 4.3 7.2 12.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TRAM_LAG1_CLN8 PF03798.16 ORY30506.1 - 9e-28 97.4 8.0 1e-27 97.2 8.0 1.0 1 0 0 1 1 1 1 TLC domain TRAM_LAG1_CLN8 PF03798.16 ORY30508.1 - 2.4e-30 105.8 13.2 2.7e-30 105.6 13.2 1.0 1 0 0 1 1 1 1 TLC domain DctQ PF04290.12 ORY30508.1 - 0.21 11.5 6.5 0.31 11.0 6.5 1.3 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF1003 PF06210.11 ORY30509.1 - 1.8e-30 105.1 0.2 1.8e-30 105.1 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1003) EF-hand_like PF09279.11 ORY30509.1 - 2.6 8.6 4.4 1.6 9.3 1.5 2.1 3 0 0 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like SOG2 PF10428.9 ORY30510.1 - 0.75 8.9 31.2 1 8.5 31.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Ank_2 PF12796.7 ORY30511.1 - 8.7e-25 87.1 0.2 1.7e-10 41.3 0.0 3.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY30511.1 - 5e-12 46.1 3.5 1.9e-05 25.1 0.1 5.0 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY30511.1 - 7.2e-08 32.6 2.1 0.00019 21.7 0.2 4.3 3 2 3 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY30511.1 - 8e-08 32.0 0.3 3.1 8.7 0.0 6.6 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 ORY30511.1 - 4.2e-07 30.1 1.3 1 9.9 0.0 4.8 4 1 0 4 4 4 2 Ankyrin repeat SH3_9 PF14604.6 ORY30513.1 - 9.7e-08 31.8 0.1 7.2e-05 22.6 0.1 3.4 3 0 0 3 3 3 1 Variant SH3 domain SH3_1 PF00018.28 ORY30513.1 - 0.00081 19.0 0.0 0.01 15.4 0.0 2.5 2 0 0 2 2 2 1 SH3 domain FAM176 PF14851.6 ORY30513.1 - 1.6 8.4 4.2 3.5 7.3 4.2 1.5 1 0 0 1 1 1 0 FAM176 family DUF4612 PF15389.6 ORY30513.1 - 5 8.2 7.5 8.7 7.4 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) Herpes_gE PF02480.16 ORY30515.1 - 0.00041 19.2 5.4 0.026 13.3 0.0 2.2 1 1 1 2 2 2 2 Alphaherpesvirus glycoprotein E TMEM52 PF14979.6 ORY30515.1 - 0.0054 16.7 0.2 0.0054 16.7 0.2 2.3 2 0 0 2 2 2 1 Transmembrane 52 TMEM132D_C PF15706.5 ORY30515.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Prominin PF05478.11 ORY30515.1 - 0.013 13.5 0.4 0.018 13.0 0.4 1.1 1 0 0 1 1 1 0 Prominin EphA2_TM PF14575.6 ORY30515.1 - 0.05 14.5 0.1 0.13 13.2 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMIE PF16038.5 ORY30515.1 - 0.28 11.1 3.9 0.49 10.3 3.9 1.3 1 0 0 1 1 1 0 TMIE protein DUF4713 PF15831.5 ORY30515.1 - 1.3 9.5 13.7 2.6 8.5 13.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4713) Ydc2-catalyt PF09159.10 ORY30516.1 - 9.1e-09 35.4 1.7 0.00048 20.0 0.8 3.1 2 1 1 3 3 3 2 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 ORY30516.1 - 0.015 15.4 0.3 0.38 10.9 0.1 2.4 2 1 0 2 2 2 0 Poxvirus A22 protein DUF3882 PF07066.11 ORY30516.1 - 0.092 12.8 0.1 0.25 11.4 0.1 1.7 1 1 0 1 1 1 0 Lactococcus phage M3 protein FKBP_C PF00254.28 ORY30517.1 - 4.8e-31 106.9 0.0 8.9e-31 106.1 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 ORY30517.1 - 7.4e-19 66.7 3.7 5.8e-06 25.9 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY30517.1 - 1.9e-14 52.5 7.7 0.00011 22.1 0.0 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY30517.1 - 2.6e-12 45.9 7.1 2e-05 24.5 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORY30517.1 - 1.2e-10 41.3 4.5 2e-06 28.1 0.5 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY30517.1 - 1.7e-10 41.0 3.1 3.5e-08 33.6 0.3 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY30517.1 - 9.9e-10 38.8 10.0 1.1e-08 35.5 1.7 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY30517.1 - 8.7e-09 34.9 4.9 0.0064 16.1 0.0 3.3 3 0 0 3 3 3 3 TPR repeat TPR_7 PF13176.6 ORY30517.1 - 1.3e-08 34.3 1.5 0.00086 19.2 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY30517.1 - 1.8e-06 27.9 3.6 0.28 11.7 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY30517.1 - 1.8e-06 28.5 7.4 0.46 11.2 0.8 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY30517.1 - 0.00065 19.9 3.8 0.0031 17.7 1.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 ORY30517.1 - 0.011 16.4 9.7 0.29 11.8 0.1 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY30517.1 - 0.018 14.9 5.5 3.9 7.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat HMGL-like PF00682.19 ORY30517.1 - 0.039 13.5 0.4 0.052 13.1 0.4 1.2 1 0 0 1 1 1 0 HMGL-like BTAD PF03704.17 ORY30517.1 - 0.082 13.3 1.5 0.44 11.0 0.2 2.3 2 1 1 3 3 3 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 ORY30517.1 - 0.1 12.7 0.9 0.17 12.1 0.2 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2148 PF09918.9 ORY30517.1 - 0.15 12.1 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) Coatomer_E PF04733.14 ORY30517.1 - 0.16 11.4 4.6 0.13 11.7 0.3 2.0 1 1 1 2 2 2 0 Coatomer epsilon subunit Fis1_TPR_C PF14853.6 ORY30517.1 - 0.29 11.3 3.9 4.9 7.3 0.0 2.6 2 1 1 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat Lactamase_B PF00753.27 ORY30518.1 - 2.2e-11 44.2 0.7 9.1e-11 42.1 0.7 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY30518.1 - 0.0018 17.8 0.2 0.0037 16.8 0.2 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain GvpO PF05800.11 ORY30518.1 - 0.14 12.1 0.3 0.38 10.7 0.3 1.7 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpO Glyco_hydro_16 PF00722.21 ORY30519.1 - 9.2e-24 83.9 0.8 1.3e-23 83.4 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 ORY30519.1 - 1.5e-07 31.8 15.9 1.5e-07 31.8 15.9 1.9 2 0 0 2 2 2 1 Chitin recognition protein ABC_tran_CTD PF16326.5 ORY30520.1 - 0.00015 21.9 0.4 0.00015 21.9 0.4 2.0 2 1 0 2 2 2 1 ABC transporter C-terminal domain Fzo_mitofusin PF04799.13 ORY30520.1 - 0.12 12.0 0.8 0.22 11.1 0.8 1.4 1 0 0 1 1 1 0 fzo-like conserved region DUF848 PF05852.11 ORY30520.1 - 0.84 9.7 7.9 0.26 11.4 4.0 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) F-box-like PF12937.7 ORY30521.1 - 0.013 15.4 0.1 0.041 13.8 0.1 1.9 1 0 0 1 1 1 0 F-box-like Phage_antitermQ PF06530.12 ORY30521.1 - 0.028 14.3 0.1 0.061 13.2 0.1 1.5 1 0 0 1 1 1 0 Phage antitermination protein Q DUF3511 PF12023.8 ORY30521.1 - 0.17 11.8 0.4 0.28 11.0 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3511) MFS_1 PF07690.16 ORY30523.1 - 1.5e-24 86.6 27.1 1.2e-18 67.2 4.7 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY30523.1 - 1.1e-08 34.4 7.4 5.5e-07 28.8 0.4 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 ORY30523.1 - 0.032 13.1 9.0 0.78 8.5 0.9 2.3 1 1 1 2 2 2 0 MFS_1 like family Herpes_UL79 PF03049.14 ORY30523.1 - 0.14 11.8 0.2 0.21 11.2 0.2 1.2 1 0 0 1 1 1 0 UL79 family SLC12 PF03522.15 ORY30524.1 - 3.3e-15 56.1 0.1 1.9e-10 40.4 0.0 2.1 2 0 0 2 2 2 2 Solute carrier family 12 AA_permease PF00324.21 ORY30524.1 - 1.4e-12 47.0 13.3 7.9e-12 44.5 13.3 2.0 1 1 0 1 1 1 1 Amino acid permease DUF4505 PF14956.6 ORY30524.1 - 1.1e-11 44.9 0.0 2.2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) TMEM237 PF15383.6 ORY30524.1 - 0.081 12.0 0.0 0.081 12.0 0.0 2.0 3 0 0 3 3 3 0 Transmembrane protein 237 SMC_N PF02463.19 ORY30525.1 - 1e-19 70.8 4.1 2.5e-19 69.6 4.3 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ORY30525.1 - 5.7e-06 26.4 0.2 8.9e-06 25.7 0.2 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 ORY30525.1 - 0.018 15.3 0.1 0.048 13.9 0.1 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit TraF PF13728.6 ORY30525.1 - 0.067 13.0 3.6 0.13 12.1 3.6 1.5 1 0 0 1 1 1 0 F plasmid transfer operon protein Endonuc_BglI PF14562.6 ORY30525.1 - 0.11 11.5 0.6 0.18 10.9 0.1 1.5 2 0 0 2 2 2 0 Restriction endonuclease BglI Histidinol_dh PF00815.20 ORY30525.1 - 0.13 11.3 0.4 0.25 10.3 0.4 1.5 1 0 0 1 1 1 0 Histidinol dehydrogenase ABC_tran PF00005.27 ORY30525.1 - 0.14 12.7 6.7 1.9 9.0 6.7 2.3 1 1 0 1 1 1 0 ABC transporter DUF3450 PF11932.8 ORY30525.1 - 2.5 7.3 12.2 0.15 11.3 4.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) BLOC1_2 PF10046.9 ORY30525.1 - 3.1 8.2 10.7 0.052 13.9 2.4 2.4 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KxDL PF10241.9 ORY30525.1 - 7.2 7.0 18.3 0.46 10.8 4.8 3.7 2 1 2 4 4 4 0 Uncharacterized conserved protein DUF5320 PF17253.2 ORY30525.1 - 7.3 7.7 5.2 34 5.6 0.1 3.2 2 1 1 3 3 3 0 Family of unknown function (DUF5320) LRR_8 PF13855.6 ORY30658.1 - 4.1e-25 87.3 42.5 3.5e-09 36.3 4.3 6.0 4 1 1 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 ORY30658.1 - 2.7e-19 68.9 38.6 0.00028 21.2 0.4 6.9 5 1 1 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY30658.1 - 5.2e-09 35.4 31.8 2.3 9.1 0.1 11.1 11 1 0 11 11 11 5 Leucine Rich Repeat LRR_6 PF13516.6 ORY30658.1 - 0.00043 20.1 27.8 2.9 8.2 0.0 9.6 10 0 0 10 10 10 3 Leucine Rich repeat TSC22 PF01166.18 ORY30659.1 - 0.0028 17.9 3.5 3.7 7.9 0.1 3.4 3 0 0 3 3 3 2 TSC-22/dip/bun family YobH PF13996.6 ORY30659.1 - 0.14 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 YobH-like protein bZIP_1 PF00170.21 ORY30659.1 - 0.36 11.0 9.9 1.6 8.9 0.2 3.1 4 0 0 4 4 4 0 bZIP transcription factor DUF3972 PF13118.6 ORY30659.1 - 0.73 10.3 3.8 4.5 7.7 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3972) DUF5094 PF17015.5 ORY30659.1 - 1 9.4 3.2 1.9 8.6 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) ABC_tran_CTD PF16326.5 ORY30659.1 - 2 8.7 4.4 4.7 7.5 2.4 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain Acyl_transf_3 PF01757.22 ORY30660.1 - 0.089 11.8 0.1 0.098 11.7 0.1 1.1 1 0 0 1 1 1 0 Acyltransferase family MTBP_mid PF14919.6 ORY30660.1 - 0.16 11.2 0.1 0.2 10.8 0.1 1.1 1 0 0 1 1 1 0 MDM2-binding Mito_carr PF00153.27 ORY30661.1 - 0.0026 17.6 0.3 0.19 11.7 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein VMA21 PF09446.10 ORY30661.1 - 7.8 6.7 8.8 1 9.5 0.4 2.9 3 1 0 3 3 3 0 VMA21-like domain LRR_8 PF13855.6 ORY30662.1 - 4.4e-23 80.8 27.3 4.6e-08 32.7 2.9 5.8 3 1 2 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 ORY30662.1 - 2e-14 53.5 32.2 0.0034 17.8 0.3 6.8 3 1 7 10 10 10 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY30662.1 - 8.6e-10 37.8 36.6 0.12 13.0 0.4 11.2 10 1 1 11 11 11 5 Leucine Rich Repeat F-box PF00646.33 ORY30662.1 - 0.057 13.3 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 F-box domain Transferase PF02458.15 ORY30663.1 - 1.8e-21 76.3 0.0 3.3e-21 75.5 0.0 1.4 1 1 0 1 1 1 1 Transferase family bZIP_Maf PF03131.17 ORY30664.1 - 0.13 12.8 6.1 0.21 12.1 6.1 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 ORY30664.1 - 0.52 10.4 11.3 1.2 9.3 11.3 1.5 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 ORY30664.1 - 4.4 7.5 11.9 12 6.1 11.9 1.6 1 1 0 1 1 1 0 bZIP transcription factor Beta-lactamase PF00144.24 ORY30665.1 - 1.6e-54 185.4 0.0 2.1e-54 185.0 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 ORY30665.1 - 0.00049 20.5 0.0 0.001 19.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Beta-lactamase2 PF13354.6 ORY30665.1 - 0.1 12.2 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Beta-lactamase enzyme family IlvN PF07991.12 ORY30665.1 - 0.14 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain DUF3471 PF11954.8 ORY30666.1 - 1.5e-07 31.8 0.0 2.6e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Thioredoxin_4 PF13462.6 ORY30666.1 - 0.0085 16.3 0.0 2 8.6 0.0 2.1 2 0 0 2 2 2 2 Thioredoxin Beta-lactamase PF00144.24 ORY30667.1 - 6e-42 144.1 0.0 8.1e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase bZIP_1 PF00170.21 ORY30668.1 - 0.00074 19.6 3.7 0.00074 19.6 3.7 3.0 3 0 0 3 3 3 2 bZIP transcription factor bZIP_2 PF07716.15 ORY30668.1 - 0.014 15.5 4.1 0.014 15.5 4.1 2.3 3 0 0 3 3 3 0 Basic region leucine zipper TSA PF03249.13 ORY30668.1 - 0.024 13.5 0.1 0.042 12.6 0.0 1.5 1 1 0 1 1 1 0 Type specific antigen DUF5094 PF17015.5 ORY30668.1 - 0.11 12.5 1.2 0.47 10.5 1.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5094) Methyltransf_4 PF02390.17 ORY30670.1 - 0.07 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase BppL_N PF18338.1 ORY30670.1 - 1.1 9.1 6.0 2.9 7.8 6.0 1.7 1 0 0 1 1 1 0 Lower baseplate protein N-terminal domain bZIP_1 PF00170.21 ORY30671.1 - 8.8e-12 45.0 10.4 1.5e-07 31.4 0.2 3.3 3 0 0 3 3 3 3 bZIP transcription factor bZIP_2 PF07716.15 ORY30671.1 - 1.5e-06 28.1 9.6 0.003 17.6 2.1 3.3 2 1 1 3 3 3 2 Basic region leucine zipper LRRFIP PF09738.9 ORY30671.1 - 0.0013 18.3 0.7 0.0018 17.8 0.7 1.1 1 0 0 1 1 1 1 LRRFIP family TSC22 PF01166.18 ORY30671.1 - 0.0015 18.8 2.2 1.2 9.5 0.3 2.5 2 0 0 2 2 2 2 TSC-22/dip/bun family HALZ PF02183.18 ORY30671.1 - 0.0016 18.7 9.7 0.13 12.6 1.0 3.2 3 0 0 3 3 3 2 Homeobox associated leucine zipper Lebercilin PF15619.6 ORY30671.1 - 0.0039 16.9 7.5 0.13 11.9 0.7 2.2 2 0 0 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease ABC_tran_CTD PF16326.5 ORY30671.1 - 0.0042 17.3 2.0 1.6 9.0 0.1 3.1 2 1 1 3 3 3 2 ABC transporter C-terminal domain Herpes_BLRF2 PF05812.12 ORY30671.1 - 0.007 16.5 1.0 0.024 14.7 0.0 2.3 3 0 0 3 3 2 1 Herpesvirus BLRF2 protein CCDC144C PF14915.6 ORY30671.1 - 0.026 13.6 4.0 0.33 10.0 0.5 2.1 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region DivIC PF04977.15 ORY30671.1 - 0.039 13.7 5.8 0.65 9.8 0.1 3.2 2 1 1 3 3 3 0 Septum formation initiator PriC PF07445.12 ORY30671.1 - 0.051 13.5 3.1 0.11 12.4 3.1 1.5 1 0 0 1 1 1 0 Primosomal replication protein priC CHDCT2 PF08074.11 ORY30671.1 - 0.058 13.6 0.5 0.12 12.5 0.5 1.6 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Ubiq_cyt_C_chap PF03981.12 ORY30671.1 - 0.069 13.2 0.4 0.63 10.1 0.1 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome C chaperone UPF0242 PF06785.11 ORY30671.1 - 0.083 13.0 5.3 0.2 11.8 2.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 ORY30671.1 - 0.11 12.6 5.0 0.44 10.6 5.0 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 ORY30671.1 - 0.13 12.5 9.9 2.1 8.5 1.5 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Fungal_TACC PF12709.7 ORY30671.1 - 0.13 12.7 2.5 12 6.4 0.4 2.5 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins K-box PF01486.17 ORY30671.1 - 0.16 12.2 3.5 1.3 9.2 0.7 2.4 2 0 0 2 2 2 0 K-box region GAS PF13851.6 ORY30671.1 - 0.24 10.7 4.1 6.7 6.0 0.4 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 ORY30671.1 - 0.3 11.1 6.7 0.28 11.2 4.7 1.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CLZ PF16526.5 ORY30671.1 - 0.41 11.0 5.5 5.2 7.5 0.8 2.6 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels YabA PF06156.13 ORY30671.1 - 0.55 10.9 3.6 12 6.6 0.6 2.3 1 1 1 2 2 2 0 Initiation control protein YabA KLRAQ PF10205.9 ORY30671.1 - 0.67 10.2 3.8 5.5 7.3 0.5 2.4 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Cep57_CLD_2 PF14197.6 ORY30671.1 - 0.81 9.8 5.2 4.4 7.5 0.8 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Csm1_N PF18504.1 ORY30671.1 - 0.86 10.0 6.2 3.8 7.9 0.7 2.9 2 1 0 3 3 3 0 Csm1 N-terminal domain Shugoshin_N PF07558.11 ORY30671.1 - 0.86 9.5 8.7 0.76 9.7 4.6 2.4 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region ZapB PF06005.12 ORY30671.1 - 1.5 9.3 5.7 18 5.8 0.4 2.6 2 1 0 2 2 2 0 Cell division protein ZapB Nnf1 PF03980.14 ORY30671.1 - 2.3 8.7 6.6 4.8 7.6 4.5 2.4 1 1 1 2 2 2 0 Nnf1 Spc24 PF08286.11 ORY30671.1 - 3 8.1 5.0 4.6 7.5 1.5 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4140 PF13600.6 ORY30671.1 - 3.2 8.3 5.0 1e+02 3.4 5.0 2.6 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) SlyX PF04102.12 ORY30671.1 - 4.3 8.0 5.0 59 4.4 0.2 3.2 2 1 0 2 2 2 0 SlyX LRR_8 PF13855.6 ORY30672.1 - 5e-07 29.4 12.0 0.0097 15.7 0.9 3.1 1 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY30672.1 - 1e-06 28.9 17.2 0.0013 19.1 1.0 3.4 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY30672.1 - 2.5 9.0 19.2 1.2 10.0 0.2 5.3 3 1 1 4 4 4 0 Leucine Rich Repeat Protoglobin PF11563.8 ORY30674.1 - 1.9e-41 141.6 0.1 2.2e-41 141.4 0.1 1.1 1 0 0 1 1 1 1 Protoglobin UPF0183 PF03676.14 ORY30675.1 - 5.7e-52 177.3 0.0 9.7e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) Glycos_transf_1 PF00534.20 ORY30675.1 - 3.3e-08 33.2 0.0 7.8e-08 32.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY30675.1 - 5e-06 27.0 0.0 1.1e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 KH_9 PF17904.1 ORY30677.1 - 0.037 14.4 0.3 0.05 14.0 0.3 1.3 1 0 0 1 1 1 0 FMRP KH0 domain PLL PF18587.1 ORY30677.1 - 0.041 14.0 0.5 0.046 13.9 0.5 1.1 1 0 0 1 1 1 0 PTX/LNS-Like (PLL) domain DSPc PF00782.20 ORY30680.1 - 6.1e-11 42.3 0.0 1e-10 41.5 0.0 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.6 ORY30681.1 - 5.4e-24 83.7 18.9 7.9e-09 35.1 4.2 4.5 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY30681.1 - 8.8e-16 57.8 24.4 0.00035 20.9 0.8 5.7 4 1 0 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY30681.1 - 8.3e-07 28.7 25.2 0.11 13.1 0.7 8.8 6 1 2 8 8 8 3 Leucine Rich Repeat F-box-like PF12937.7 ORY30681.1 - 0.0017 18.2 0.2 0.0037 17.1 0.2 1.5 1 0 0 1 1 1 1 F-box-like PHF12_MRG_bd PF16737.5 ORY30681.1 - 0.011 15.4 0.8 0.02 14.6 0.8 1.5 1 0 0 1 1 1 0 PHD finger protein 12 MRG binding domain LRR_6 PF13516.6 ORY30681.1 - 0.15 12.2 25.6 1.5 9.1 0.8 7.1 7 0 0 7 7 7 0 Leucine Rich repeat LRR_8 PF13855.6 ORY30682.1 - 1.2e-13 50.6 9.7 9.3e-05 22.1 0.3 4.2 3 2 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 ORY30682.1 - 2.1e-08 34.3 10.1 0.028 14.9 0.1 4.6 1 1 6 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY30682.1 - 3.2e-05 23.9 8.2 19 6.3 0.0 6.7 7 0 0 7 7 7 2 Leucine Rich Repeat F-box-like PF12937.7 ORY30682.1 - 0.0012 18.7 0.1 0.003 17.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 ORY30682.1 - 0.0086 16.1 8.0 24 5.3 0.0 6.3 7 0 0 7 7 7 1 Leucine Rich repeat F-box PF00646.33 ORY30682.1 - 0.012 15.4 0.0 0.038 13.9 0.0 1.8 1 0 0 1 1 1 0 F-box domain SDA1 PF05285.12 ORY30683.1 - 0.0031 17.0 9.5 0.0043 16.5 9.5 1.4 1 0 0 1 1 1 1 SDA1 KDZ PF18758.1 ORY30684.1 - 4e-19 69.1 0.0 9.2e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Topoisom_I PF01028.20 ORY30685.1 - 1e-94 316.2 1.8 1e-94 316.2 1.8 2.7 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 ORY30685.1 - 2e-93 311.8 1.2 2e-93 311.8 1.2 3.1 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 ORY30685.1 - 4.8e-29 100.1 0.6 4.8e-29 100.1 0.6 2.9 3 1 1 4 4 4 1 C-terminal topoisomerase domain Matrilin_ccoil PF10393.9 ORY30685.1 - 0.0055 16.5 0.9 0.012 15.4 0.9 1.6 1 0 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin DUF5344 PF17279.2 ORY30685.1 - 0.0081 16.7 1.6 0.4 11.3 0.1 3.0 2 0 0 2 2 2 1 Family of unknown function (DUF5344) Ras PF00071.22 ORY30686.1 - 2.7e-55 186.4 0.0 3.1e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY30686.1 - 6.6e-23 81.2 0.0 8.9e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY30686.1 - 1.5e-08 34.3 0.0 1.8e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY30686.1 - 0.0039 16.8 0.0 0.017 14.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SF3b10 PF07189.11 ORY30687.1 - 3.8e-36 123.0 0.0 4.2e-36 122.9 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Ras PF00071.22 ORY30688.1 - 3.5e-54 182.8 0.0 4e-54 182.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY30688.1 - 9.9e-24 83.9 0.0 1.5e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY30688.1 - 5.3e-10 39.0 0.0 6.4e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family ANAPC4_WD40 PF12894.7 ORY30689.1 - 7.2e-10 39.0 6.1 1.2e-06 28.7 0.7 5.0 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.20 ORY30689.1 - 2.4e-07 30.7 15.0 0.5 10.2 2.1 6.2 4 1 2 6 6 6 3 Region in Clathrin and VPS TPR_19 PF14559.6 ORY30689.1 - 1.7e-05 25.2 6.9 26 5.4 0.0 7.0 6 2 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.32 ORY30689.1 - 2.1e-05 25.2 7.3 0.012 16.5 0.0 4.9 5 0 0 5 5 3 1 WD domain, G-beta repeat TPR_14 PF13428.6 ORY30689.1 - 0.001 19.7 12.2 90 4.3 0.0 8.8 9 1 1 10 10 9 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 ORY30689.1 - 0.0025 16.9 15.7 0.0055 15.8 0.1 5.4 4 1 1 5 5 5 1 Coatomer WD associated region TPR_7 PF13176.6 ORY30689.1 - 0.005 16.8 12.6 1.8 8.8 0.7 7.9 8 2 2 10 10 9 1 Tetratricopeptide repeat PPR PF01535.20 ORY30689.1 - 0.017 15.4 7.9 0.51 10.7 0.1 6.2 7 1 1 8 8 5 0 PPR repeat Mcl1_mid PF12341.8 ORY30689.1 - 0.044 13.1 4.8 16 4.7 1.2 4.2 1 1 1 3 3 3 0 Minichromosome loss protein, Mcl1, middle region PPR_1 PF12854.7 ORY30689.1 - 0.058 13.1 2.4 26 4.6 0.0 4.6 5 0 0 5 5 5 0 PPR repeat SNAP PF14938.6 ORY30689.1 - 0.064 12.7 26.1 0.091 12.2 2.3 5.7 3 2 2 5 5 5 0 Soluble NSF attachment protein, SNAP Nbas_N PF15492.6 ORY30689.1 - 0.076 12.3 0.5 4.8 6.4 0.0 3.2 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal WD40_3 PF15911.5 ORY30689.1 - 0.16 12.0 0.0 1.7 8.7 0.0 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat TPR_2 PF07719.17 ORY30689.1 - 0.16 12.1 27.8 14 6.1 2.5 9.8 10 1 1 11 11 10 0 Tetratricopeptide repeat PPR_2 PF13041.6 ORY30689.1 - 0.38 11.0 6.0 0.74 10.1 0.1 4.5 7 0 0 7 7 5 0 PPR repeat family TPR_8 PF13181.6 ORY30689.1 - 0.6 10.5 10.2 23 5.5 0.0 6.2 5 1 0 5 5 4 0 Tetratricopeptide repeat MIT PF04212.18 ORY30689.1 - 1.3 9.2 12.9 9.6 6.4 0.0 4.9 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 ORY30689.1 - 1.3 9.3 15.0 1.4 9.2 0.1 6.6 5 3 2 8 8 8 0 Anaphase-promoting complex, cyclosome, subunit 3 Vps39_1 PF10366.9 ORY30689.1 - 1.7 8.9 4.0 41 4.5 0.0 4.2 4 1 1 5 5 5 0 Vacuolar sorting protein 39 domain 1 RPN7 PF10602.9 ORY30689.1 - 2.9 7.6 11.1 4.6 6.9 0.0 5.5 4 2 0 4 4 4 0 26S proteasome subunit RPN7 Dpy-30 PF05186.13 ORY30690.1 - 7.5e-17 60.7 0.1 1.3e-16 60.0 0.1 1.4 1 0 0 1 1 1 1 Dpy-30 motif Peptidase_C48 PF02902.19 ORY30691.1 - 2.7e-43 148.3 0.6 3.5e-43 148.0 0.6 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.13 ORY30691.1 - 0.003 16.3 1.1 0.028 13.1 0.2 2.1 2 0 0 2 2 2 1 Vaccinia virus I7 processing peptidase LupA PF18242.1 ORY30691.1 - 0.059 13.0 0.1 0.097 12.3 0.1 1.3 1 0 0 1 1 1 0 Legionella ubiquitin-specific protease A domain Spy1 PF11357.8 ORY30691.1 - 0.059 13.7 0.3 2.3 8.5 0.1 2.9 2 1 0 2 2 2 0 Cell cycle regulatory protein Ribosomal_L11 PF00298.19 ORY30691.1 - 0.23 12.0 0.0 30 5.2 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L11, RNA binding domain WD40 PF00400.32 ORY30692.1 - 9.5e-15 54.7 12.1 0.016 16.1 0.0 7.1 5 2 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY30692.1 - 5.9e-07 29.7 0.0 0.00039 20.7 0.0 3.6 1 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY30692.1 - 0.0014 18.1 0.0 0.21 10.8 0.0 2.5 3 0 0 3 3 3 2 WD40-like domain eIF2A PF08662.11 ORY30692.1 - 0.035 14.0 0.0 5.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF3931 PF13082.6 ORY30692.1 - 0.12 12.5 0.1 6.5 7.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3931) Nup160 PF11715.8 ORY30692.1 - 0.2 10.2 1.4 1 7.9 0.1 2.5 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PGAP1 PF07819.13 ORY30693.1 - 1.1e-06 28.5 0.0 1.4e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 ORY30693.1 - 2.5e-05 23.9 0.2 5.1e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF915 PF06028.11 ORY30693.1 - 0.0061 15.9 0.5 0.28 10.5 0.0 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF2974 PF11187.8 ORY30693.1 - 0.009 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 ORY30693.1 - 0.016 14.5 0.1 0.28 10.4 0.1 2.6 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Lipase PF00151.19 ORY30693.1 - 0.095 12.0 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipase Tyrosinase PF00264.20 ORY30694.1 - 2.8e-22 80.1 0.0 5.6e-22 79.1 0.0 1.5 1 1 0 1 1 1 1 Common central domain of tyrosinase Tyosinase_C PF18132.1 ORY30694.1 - 0.00013 22.6 0.1 0.0014 19.3 0.1 2.6 2 1 0 2 2 2 1 Tyosinase C-terminal domain Homeodomain PF00046.29 ORY30695.1 - 1.4e-09 37.6 0.2 2.3e-09 36.9 0.2 1.2 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY30695.1 - 9.2e-07 28.7 0.1 1.8e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain RhoGAP PF00620.27 ORY30696.1 - 1.2e-40 138.9 0.4 2.7e-40 137.6 0.4 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 ORY30696.1 - 1.2e-23 83.1 35.8 3.2e-09 36.9 4.3 4.5 4 0 0 4 4 4 4 LIM domain RAI16-like PF10257.9 ORY30696.1 - 0.0015 17.5 2.1 0.027 13.3 0.1 2.9 3 0 0 3 3 3 1 Retinoic acid induced 16-like protein BTB PF00651.31 ORY30697.1 - 2.6e-13 50.2 0.0 5.4e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Ion_trans PF00520.31 ORY30698.1 - 4.4e-11 42.5 18.3 7.2e-11 41.8 18.3 1.4 1 0 0 1 1 1 1 Ion transport protein Ank PF00023.30 ORY30698.1 - 9.1e-08 32.2 0.0 6.4e-06 26.4 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 ORY30698.1 - 1.8e-07 30.9 0.1 4.1e-06 26.7 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 ORY30698.1 - 6.2e-07 29.9 0.0 9.2e-06 26.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY30698.1 - 6.8e-07 29.4 0.3 4.5e-06 26.8 0.3 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY30698.1 - 2.2e-06 28.1 0.4 0.0034 17.9 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Asp PF00026.23 ORY30699.1 - 1.9e-42 145.8 3.7 3.1e-41 141.8 3.7 2.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease PAN_1 PF00024.26 ORY30699.1 - 3.7e-23 81.3 17.1 1.8e-07 31.0 0.2 5.5 5 1 0 5 5 5 4 PAN domain PAN_4 PF14295.6 ORY30699.1 - 2e-16 59.6 30.7 1.1e-07 31.6 2.2 5.5 5 0 0 5 5 5 4 PAN domain PAN_3 PF08277.12 ORY30699.1 - 0.017 14.9 33.9 0.019 14.8 1.6 5.5 6 0 0 6 6 6 0 PAN-like domain LRR_8 PF13855.6 ORY30700.1 - 3.2e-15 55.6 8.1 1.8e-06 27.6 0.6 4.5 2 1 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 ORY30700.1 - 1.1e-11 44.7 3.2 0.02 15.3 0.0 4.6 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORY30700.1 - 1.6e-06 27.9 0.2 6.7e-06 25.9 0.1 2.2 2 0 0 2 2 2 1 F-box-like LRR_1 PF00560.33 ORY30700.1 - 1.9e-06 27.6 11.8 1.2 9.9 0.1 6.9 7 1 0 7 7 7 3 Leucine Rich Repeat F-box PF00646.33 ORY30700.1 - 2.2e-06 27.4 0.1 4.6e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 F-box domain Ank_2 PF12796.7 ORY30702.1 - 4.1e-12 46.5 0.0 2.6e-05 24.7 0.0 3.6 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORY30702.1 - 5e-12 45.7 0.1 0.0003 21.1 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 ORY30702.1 - 8.5e-11 41.1 0.1 0.11 13.2 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 ORY30702.1 - 6e-09 36.3 0.4 0.035 14.7 0.0 5.4 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY30702.1 - 1.7e-07 31.4 1.0 0.12 12.8 0.0 4.6 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ion_trans PF00520.31 ORY30702.1 - 0.00012 21.5 12.7 0.00047 19.5 12.3 2.0 1 1 1 2 2 2 1 Ion transport protein PSI_8 PF00796.18 ORY30702.1 - 5.6 6.9 7.1 1.3 8.9 2.5 2.2 2 0 0 2 2 2 0 Photosystem I reaction centre subunit VIII Ion_trans PF00520.31 ORY30703.1 - 2.2e-05 23.8 9.0 3.1e-05 23.3 9.0 1.2 1 0 0 1 1 1 1 Ion transport protein Glyco_hyd_101C PF17451.2 ORY30703.1 - 0.072 13.4 0.1 0.12 12.7 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain Ank PF00023.30 ORY30704.1 - 4.4e-08 33.2 0.0 5.4e-05 23.4 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 ORY30704.1 - 2.6e-06 27.3 0.1 0.047 14.2 0.1 3.8 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 ORY30704.1 - 7.4e-06 26.5 0.0 5e-05 23.8 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY30704.1 - 0.0031 18.1 0.3 1.3 9.7 0.1 3.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Corona_NS3b PF03053.14 ORY30704.1 - 0.0046 16.7 0.5 0.0092 15.8 0.3 1.5 2 0 0 2 2 2 1 ORF3b coronavirus protein Ank_5 PF13857.6 ORY30704.1 - 0.049 14.0 0.0 35 4.9 0.0 3.4 3 0 0 3 3 3 0 Ankyrin repeats (many copies) GHMP_kinases_N PF00288.26 ORY30705.1 - 7.8e-13 48.5 0.4 1.4e-11 44.5 0.3 3.0 2 1 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ORY30705.1 - 4.3e-07 30.2 0.0 1.4e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal DUF4455 PF14643.6 ORY30705.1 - 0.019 13.6 1.3 0.028 13.1 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) PilJ PF13675.6 ORY30705.1 - 0.16 12.0 0.5 0.32 11.0 0.5 1.5 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term POT1PC PF16686.5 ORY30706.1 - 1.1e-11 44.8 0.1 1.5e-07 31.4 0.1 3.1 2 1 0 2 2 2 2 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 ORY30706.1 - 8.8e-11 41.8 0.1 1.8e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.25 ORY30706.1 - 0.12 12.3 0.0 1.8 8.6 0.0 2.8 3 1 1 4 4 4 0 OB-fold nucleic acid binding domain Seryl_tRNA_N PF02403.22 ORY30707.1 - 0.19 12.0 5.6 0.79 10.0 5.6 1.9 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain p450 PF00067.22 ORY30708.1 - 1.1e-68 232.1 0.3 1.5e-68 231.7 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 Asp PF00026.23 ORY30709.1 - 2.5e-61 207.8 0.9 3.1e-61 207.5 0.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY30709.1 - 0.00035 20.8 0.9 0.012 15.9 0.4 2.5 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORY30709.1 - 0.039 14.6 0.3 4.9 7.9 0.0 2.7 2 0 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.6 ORY30709.1 - 0.09 12.5 0.0 0.52 10.1 0.0 2.0 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal ABC_tran PF00005.27 ORY30710.1 - 1.8e-28 99.8 0.0 3.3e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 ORY30710.1 - 1.4e-16 60.5 26.9 2.4e-16 59.8 25.3 2.1 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 ORY30710.1 - 8.8e-16 58.6 3.0 1.9e-10 41.1 0.0 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY30710.1 - 2e-05 24.2 0.0 4.6e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 ORY30710.1 - 0.00026 20.8 0.0 0.096 12.4 0.0 2.3 1 1 1 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 ORY30710.1 - 0.0021 18.6 0.0 0.004 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY30710.1 - 0.0069 16.1 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 ORY30710.1 - 0.022 14.4 0.1 0.04 13.5 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 ORY30710.1 - 0.084 12.6 0.1 0.24 11.2 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_13 PF13166.6 ORY30710.1 - 0.1 11.2 0.0 3 6.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ORY30710.1 - 0.43 11.0 2.5 20 5.6 0.2 3.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NDUF_B4 PF07225.12 ORY30711.1 - 0.0075 16.2 0.0 0.0081 16.0 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) RRM_1 PF00076.22 ORY30712.1 - 8.6e-16 57.5 0.0 2.6e-15 56.0 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Kinesin PF00225.23 ORY30713.1 - 5.8e-55 186.5 2.4 2.2e-30 105.7 0.3 3.7 2 1 1 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 ORY30713.1 - 3.6e-20 72.4 0.0 7.5e-18 64.9 0.0 2.9 1 1 0 1 1 1 1 Microtubule binding AAA_30 PF13604.6 ORY30713.1 - 0.0042 16.8 0.3 0.33 10.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain HR1 PF02185.16 ORY30713.1 - 0.014 15.5 0.4 0.082 13.0 0.0 2.3 2 0 0 2 2 2 0 Hr1 repeat AAA_22 PF13401.6 ORY30713.1 - 0.16 12.3 1.5 1.1 9.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain DUF2508 PF10704.9 ORY30713.1 - 0.24 11.6 3.9 0.92 9.7 3.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) TPR_MLP1_2 PF07926.12 ORY30713.1 - 8.1 6.5 10.4 28 4.8 0.5 2.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Pep_deformylase PF01327.21 ORY30714.1 - 1.6e-22 79.8 0.0 2e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Polypeptide deformylase RraA-like PF03737.15 ORY30715.1 - 4e-19 69.2 2.3 5.6e-19 68.8 2.3 1.2 1 0 0 1 1 1 1 Aldolase/RraA RuBisCo_chap_C PF18087.1 ORY30715.1 - 0.013 15.1 0.3 0.024 14.3 0.3 1.4 1 0 0 1 1 1 0 Rubisco Assembly chaperone C-terminal domain Ank PF00023.30 ORY30716.1 - 0.007 16.8 0.1 0.034 14.6 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 ORY30716.1 - 0.011 16.2 0.0 0.086 13.4 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat LRR_4 PF12799.7 ORY30718.1 - 0.00015 22.1 1.1 0.069 13.6 0.0 2.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY30718.1 - 0.0074 16.0 0.4 0.036 13.8 0.3 1.9 1 1 0 1 1 1 1 Leucine rich repeat LRR_8 PF13855.6 ORY30719.1 - 9.8e-16 57.3 39.7 9.8e-10 38.1 5.0 3.8 1 1 5 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 ORY30719.1 - 6.1e-11 42.4 20.3 0.00013 22.3 2.7 4.0 2 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY30719.1 - 1.3e-07 31.1 18.1 1.4 9.7 0.6 6.5 7 0 0 7 7 7 5 Leucine Rich Repeat LRR_6 PF13516.6 ORY30719.1 - 0.0022 17.9 19.5 0.91 9.7 0.1 5.7 6 0 0 6 6 6 3 Leucine Rich repeat LRR_8 PF13855.6 ORY30720.1 - 4.7e-24 83.9 39.3 8.9e-09 35.0 7.9 6.3 4 1 3 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 ORY30720.1 - 5.1e-20 71.2 40.6 9.6e-06 25.9 2.4 6.8 4 1 0 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY30720.1 - 5.4e-12 44.5 29.8 0.83 10.4 0.2 11.1 10 1 1 11 11 11 6 Leucine Rich Repeat LRR_6 PF13516.6 ORY30720.1 - 0.00029 20.7 33.6 0.81 9.9 0.3 9.0 9 0 0 9 9 9 3 Leucine Rich repeat F-box-like PF12937.7 ORY30720.1 - 0.14 12.1 0.0 0.51 10.3 0.0 2.1 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 ORY30720.1 - 0.33 10.9 2.1 0.61 10.0 0.0 2.6 3 0 0 3 3 3 0 F-box domain LRR_8 PF13855.6 ORY30721.1 - 3.9e-31 106.6 48.7 1e-08 34.8 3.1 9.0 5 1 5 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 ORY30721.1 - 3.7e-23 81.2 54.6 0.00016 22.0 2.4 10.2 6 2 2 10 10 10 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY30721.1 - 1.7e-08 33.9 58.3 1.9 9.4 1.9 15.7 16 1 0 16 16 16 4 Leucine Rich Repeat LRR_6 PF13516.6 ORY30721.1 - 0.0003 20.6 45.0 0.93 9.7 0.1 12.4 13 0 0 13 13 13 4 Leucine Rich repeat F-box PF00646.33 ORY30721.1 - 0.011 15.6 0.2 0.037 13.9 0.2 1.9 1 0 0 1 1 1 0 F-box domain LRR_9 PF14580.6 ORY30721.1 - 0.03 13.8 1.7 1.4 8.4 0.0 3.0 1 1 0 2 2 2 0 Leucine-rich repeat Glyco_hydro_18 PF00704.28 ORY30722.1 - 7.4e-19 68.6 0.0 1.4e-18 67.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MBOAT_2 PF13813.6 ORY30723.1 - 0.013 15.7 0.3 0.032 14.5 0.3 1.7 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family Pkinase PF00069.25 ORY30724.1 - 1.4e-72 244.2 0.0 2.2e-72 243.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY30724.1 - 7.4e-43 146.7 0.0 1.2e-42 146.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 ORY30724.1 - 1.9e-36 124.0 2.9 2.2e-19 69.4 0.4 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 ORY30724.1 - 1.9e-06 27.4 0.0 3.4e-05 23.3 0.0 2.4 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 ORY30724.1 - 0.047 13.3 3.3 0.19 11.3 0.3 2.4 1 1 1 2 2 2 0 RIO1 family PX PF00787.24 ORY30725.1 - 2.3e-24 85.6 0.0 2.7e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 PX domain DEAD PF00270.29 ORY30726.1 - 2.5e-40 138.1 0.9 3.3e-40 137.7 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY30726.1 - 3.9e-16 59.4 0.0 1.7e-15 57.3 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY30726.1 - 9.3e-06 25.7 0.8 2.3e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4207 PF13904.6 ORY30726.1 - 9.1e-05 22.3 16.4 0.00014 21.7 16.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4207) DUF4217 PF13959.6 ORY30726.1 - 0.00014 22.0 0.0 0.00037 20.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.6 ORY30726.1 - 0.017 15.4 0.0 0.06 13.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain NTF2 PF02136.20 ORY30726.1 - 0.078 13.5 0.0 0.22 12.1 0.0 1.7 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain DAG_kinase_N PF14513.6 ORY30726.1 - 0.28 11.4 2.2 0.48 10.6 2.2 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus Tyrosinase PF00264.20 ORY30727.1 - 6e-32 111.7 0.1 8.9e-31 107.9 0.1 2.1 1 1 0 1 1 1 1 Common central domain of tyrosinase PAP2 PF01569.21 ORY30729.1 - 0.15 11.9 4.0 0.25 11.1 1.8 2.1 2 0 0 2 2 2 0 PAP2 superfamily cobW PF02492.19 ORY30733.1 - 4.5e-42 143.6 0.1 5.9e-42 143.2 0.1 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 ORY30733.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 ORY30733.1 - 0.041 13.8 0.2 10 6.0 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase CobW_C PF07683.14 ORY30733.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain Longin PF13774.6 ORY30734.1 - 8e-25 86.7 0.1 1.6e-24 85.7 0.1 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 ORY30734.1 - 2.8e-17 62.3 0.1 5.6e-17 61.3 0.1 1.5 1 0 0 1 1 1 1 Synaptobrevin COX7B PF05392.11 ORY30734.1 - 0.0014 18.3 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 2 Cytochrome C oxidase chain VIIB iPGM_N PF06415.13 ORY30734.1 - 0.028 13.9 0.4 0.53 9.7 0.1 2.1 1 1 1 2 2 2 0 BPG-independent PGAM N-terminus (iPGM_N) 60KD_IMP PF02096.20 ORY30734.1 - 0.12 12.2 1.9 0.35 10.8 0.1 2.2 2 0 0 2 2 2 0 60Kd inner membrane protein Sec5 PF15469.6 ORY30734.1 - 0.24 11.2 4.1 0.09 12.6 1.9 1.5 2 0 0 2 2 2 0 Exocyst complex component Sec5 Aminotran_1_2 PF00155.21 ORY30735.1 - 1.5e-37 129.6 0.0 1.9e-37 129.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II HNH_2 PF13391.6 ORY30736.1 - 8.6e-13 48.2 0.7 1.7e-12 47.2 0.7 1.5 1 0 0 1 1 1 1 HNH endonuclease Glyco_hydro_18 PF00704.28 ORY30737.1 - 3.3e-16 59.9 0.7 2.1e-15 57.3 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 LRR_8 PF13855.6 ORY30738.1 - 4.7e-17 61.5 4.5 4e-08 32.9 1.2 3.3 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY30738.1 - 2.2e-15 56.5 8.1 2.1e-05 24.8 0.3 4.3 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY30738.1 - 2.4e-09 36.5 8.9 1.5 9.7 0.0 7.0 8 0 0 8 8 8 4 Leucine Rich Repeat LRR_6 PF13516.6 ORY30738.1 - 0.0059 16.6 6.6 57 4.1 0.0 5.5 6 0 0 6 6 6 0 Leucine Rich repeat LRR_2 PF07723.13 ORY30738.1 - 0.047 14.4 0.6 5.2 7.9 0.0 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.6 ORY30739.1 - 5.4e-09 35.7 20.2 6.1e-06 25.9 6.3 3.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY30739.1 - 3.8e-06 27.2 23.7 0.0022 18.4 3.5 4.2 2 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY30739.1 - 0.0023 18.2 25.8 5.8 7.9 0.6 6.1 6 0 0 6 6 6 4 Leucine Rich Repeat MASE2 PF05230.11 ORY30740.1 - 0.062 13.4 0.9 0.18 11.9 0.9 1.7 1 0 0 1 1 1 0 MASE2 domain EamA PF00892.20 ORY30740.1 - 1.8 8.7 11.1 0.46 10.6 3.2 3.2 3 0 0 3 3 3 0 EamA-like transporter family Trypan_glycop_C PF10659.9 ORY30741.1 - 0.25 11.7 2.5 5 7.6 0.3 2.6 3 0 0 3 3 3 0 Trypanosome variant surface glycoprotein C-terminal domain HIF-1a_CTAD PF08778.10 ORY30741.1 - 1.4 8.6 0.0 1.4 8.6 0.0 4.5 6 1 1 7 7 7 0 HIF-1 alpha C terminal transactivation domain zf-PARP PF00645.18 ORY30742.1 - 0.001 19.9 0.1 0.0017 19.1 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF3823_C PF18003.1 ORY30743.1 - 0.015 16.0 2.7 1.4 9.6 2.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3823_C) DUF1764 PF08576.10 ORY30743.1 - 2.6 9.0 9.8 18 6.3 9.8 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF4199 PF13858.6 ORY30746.1 - 0.15 12.5 1.7 1 9.7 1.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) Acetyltransf_9 PF13527.7 ORY30747.1 - 2e-05 24.7 0.0 0.00023 21.3 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain SDA1 PF05285.12 ORY30888.1 - 2.3 7.5 15.5 3.3 7.1 15.5 1.3 1 0 0 1 1 1 0 SDA1 TPK_B1_binding PF04265.14 ORY30889.1 - 0.0018 18.0 0.0 3.1 7.6 0.0 2.6 2 0 0 2 2 2 2 Thiamin pyrophosphokinase, vitamin B1 binding domain DUF5378 PF17349.2 ORY30889.1 - 0.033 13.5 0.0 9.2 5.5 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5378) RecQ_Zn_bind PF16124.5 ORY30889.1 - 0.035 14.8 0.0 0.26 12.1 0.0 2.5 1 0 0 1 1 1 0 RecQ zinc-binding DUF3952 PF13130.6 ORY30889.1 - 0.048 13.9 0.0 21 5.3 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3952) YtxH PF12732.7 ORY30889.1 - 0.19 12.3 1.4 54 4.4 0.0 3.7 3 0 0 3 3 3 0 YtxH-like protein Nop10p PF04135.12 ORY30890.1 - 5.1e-22 77.7 0.9 5.9e-22 77.5 0.9 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family AAA PF00004.29 ORY30892.1 - 6e-42 143.2 0.0 1e-41 142.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY30892.1 - 9.6e-07 28.5 0.0 1.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 ORY30892.1 - 1e-05 25.5 0.0 0.00021 21.3 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ORY30892.1 - 0.00029 20.6 0.0 0.00068 19.4 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY30892.1 - 0.00034 21.0 0.1 0.015 15.7 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 ORY30892.1 - 0.00055 20.5 0.0 0.00089 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 ORY30892.1 - 0.0006 19.6 0.0 0.00088 19.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 ORY30892.1 - 0.00064 19.8 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY30892.1 - 0.00066 19.8 0.0 0.0013 18.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY30892.1 - 0.00072 19.8 0.1 0.014 15.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 ORY30892.1 - 0.00078 18.7 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 ORY30892.1 - 0.002 17.5 0.3 0.0043 16.5 0.3 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 ORY30892.1 - 0.0028 17.8 0.0 0.011 15.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 ORY30892.1 - 0.024 14.3 0.0 0.055 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 ORY30892.1 - 0.026 14.2 0.0 0.083 12.6 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 ORY30892.1 - 0.04 13.4 0.0 0.094 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 ORY30892.1 - 0.041 13.3 0.7 0.12 11.8 0.3 1.8 2 1 0 2 2 2 0 PhoH-like protein AAA_6 PF12774.7 ORY30892.1 - 0.046 12.7 0.0 0.065 12.2 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region AAA_25 PF13481.6 ORY30892.1 - 0.05 13.2 0.2 0.2 11.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 ORY30892.1 - 0.074 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 ORY30892.1 - 0.074 13.4 0.0 0.21 12.0 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_3 PF07726.11 ORY30892.1 - 0.076 12.9 0.0 0.13 12.1 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 ORY30892.1 - 0.08 13.4 0.1 0.16 12.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 ORY30892.1 - 0.16 11.1 0.0 0.33 10.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF815) LRR_8 PF13855.6 ORY30893.1 - 4.5e-08 32.7 3.8 0.00015 21.4 0.1 3.8 2 1 2 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 ORY30893.1 - 1.5e-07 31.6 0.8 0.015 15.7 0.1 3.3 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY30893.1 - 1.3e-06 28.1 4.8 4.6 8.2 0.3 5.4 5 0 0 5 5 5 3 Leucine Rich Repeat F-box PF00646.33 ORY30893.1 - 0.00073 19.4 1.0 0.0016 18.3 1.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY30893.1 - 0.091 12.7 0.7 0.17 11.8 0.7 1.5 1 0 0 1 1 1 0 F-box-like Enkurin PF13864.6 ORY30895.1 - 7.3e-09 36.0 0.2 2.7e-08 34.1 0.2 2.1 1 1 0 1 1 1 1 Calmodulin-binding Pkinase PF00069.25 ORY30896.1 - 2e-68 230.7 0.0 4e-68 229.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY30896.1 - 4.8e-34 117.8 0.0 6.9e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY30896.1 - 7.8e-06 25.4 0.0 1.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY30896.1 - 0.05 13.5 0.0 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Fanconi_A_N PF15865.5 ORY30897.1 - 0.037 13.4 0.1 0.062 12.7 0.1 1.3 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus UQ_con PF00179.26 ORY30899.1 - 6.6e-25 87.4 0.0 7.3e-25 87.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ank_2 PF12796.7 ORY30900.1 - 3.6e-17 62.7 5.3 2.9e-07 31.0 0.1 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY30900.1 - 4.7e-10 39.5 8.4 0.36 11.2 0.0 6.4 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY30900.1 - 7.5e-09 36.0 4.3 0.016 15.8 0.1 5.0 2 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY30900.1 - 6e-06 26.2 10.3 10 7.0 0.0 7.2 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 ORY30900.1 - 0.023 15.1 11.0 30 5.3 0.0 6.4 5 3 2 7 7 7 0 Ankyrin repeat Colicin_im PF03857.13 ORY30901.1 - 0.008 16.1 0.3 0.011 15.7 0.3 1.3 1 0 0 1 1 1 1 Colicin immunity protein ETC_C1_NDUFA5 PF04716.14 ORY30901.1 - 0.14 12.0 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 ETC complex I subunit conserved region Renin_r PF07850.14 ORY30902.1 - 0.17 12.5 1.4 1.6 9.4 0.2 2.2 2 0 0 2 2 2 0 Renin receptor-like protein DUF3437 PF11919.8 ORY30903.1 - 0.008 16.1 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HemY_N PF07219.13 ORY30903.1 - 0.1 12.8 2.8 0.16 12.2 2.8 1.4 1 0 0 1 1 1 0 HemY protein N-terminus HNH_2 PF13391.6 ORY30904.1 - 3e-10 40.1 5.3 6.8e-10 38.9 5.3 1.6 1 0 0 1 1 1 1 HNH endonuclease Ank_2 PF12796.7 ORY30905.1 - 3.6e-23 82.0 0.2 1.7e-12 47.7 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY30905.1 - 3.5e-16 59.4 0.7 1.2e-07 32.1 0.0 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY30905.1 - 5.8e-14 52.0 0.7 9.4e-09 35.4 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY30905.1 - 6.7e-13 48.5 1.1 2.4e-06 27.7 0.2 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 ORY30905.1 - 1.7e-12 46.3 0.5 4.3e-06 26.7 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeat Mito_carr PF00153.27 ORY30906.1 - 2.8e-51 171.4 1.1 2.6e-17 62.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3262 PF11660.8 ORY30906.1 - 0.025 15.0 0.3 0.054 13.9 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3262) ERAP1_C PF11838.8 ORY30907.1 - 0.012 15.2 0.0 0.034 13.7 0.0 1.9 1 0 0 1 1 1 0 ERAP1-like C-terminal domain DUF1294 PF06961.13 ORY30908.1 - 1.7e-21 76.2 0.6 1.7e-21 76.2 0.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1294) CPSase_L_D2 PF02786.17 ORY30909.1 - 1.1e-75 253.8 0.0 1.7e-75 253.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 ORY30909.1 - 1.6e-61 207.5 0.0 2.3e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 ORY30909.1 - 4.5e-37 127.0 0.0 9.1e-37 126.0 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORY30909.1 - 2.8e-29 101.4 0.0 1e-28 99.5 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 ORY30909.1 - 3.4e-26 92.4 0.0 7e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 ORY30909.1 - 6.8e-19 67.5 11.4 6.4e-16 58.0 4.2 2.2 1 1 1 2 2 2 2 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 ORY30909.1 - 1e-11 44.5 0.9 3.1e-05 23.7 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 ORY30909.1 - 8.5e-08 32.0 0.0 2e-07 30.8 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORY30909.1 - 4.6e-07 29.6 0.0 9.2e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 ORY30909.1 - 0.0001 21.9 0.0 0.00038 20.1 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 ORY30909.1 - 0.00013 22.1 0.0 0.00023 21.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 ORY30909.1 - 0.00019 22.1 0.9 0.9 10.3 0.2 2.7 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 ORY30909.1 - 0.00048 19.4 0.3 0.39 9.9 0.0 2.3 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATPgrasp_Ter PF15632.6 ORY30909.1 - 0.0031 17.3 0.1 0.041 13.6 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATPgrasp_ST PF14397.6 ORY30909.1 - 0.007 15.7 0.0 0.06 12.6 0.0 2.2 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 ORY30909.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain RnfC_N PF13375.6 ORY30909.1 - 0.048 13.6 1.9 1.3 9.0 0.5 2.9 2 1 1 3 3 3 0 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.9 ORY30909.1 - 0.071 13.1 0.1 1.7 8.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) Glyco_trans_4_2 PF13477.6 ORY30909.1 - 0.15 12.1 0.3 8.1 6.5 0.1 2.6 2 0 0 2 2 2 0 Glycosyl transferase 4-like Peptidase_M23 PF01551.22 ORY30909.1 - 0.34 11.1 4.4 2.8 8.2 0.5 3.4 2 1 0 2 2 2 0 Peptidase family M23 AAA_19 PF13245.6 ORY30910.1 - 0.0025 18.1 0.1 0.049 14.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY30910.1 - 0.085 13.2 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ORY30910.1 - 0.16 12.3 0.1 0.95 9.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 ORY30911.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF5540 PF17694.1 ORY30911.1 - 0.095 13.2 0.1 1.4 9.5 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5540) DUF4632 PF15451.6 ORY30912.1 - 0.066 13.3 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) DUF1179 PF06678.11 ORY30912.1 - 0.26 11.3 2.5 0.89 9.6 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1179) Pkinase_Tyr PF07714.17 ORY30913.1 - 2.5e-29 102.3 0.0 3.2e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORY30913.1 - 7.9e-21 74.6 0.0 9.7e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 ORY30913.1 - 0.0087 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY30913.1 - 0.042 13.2 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY30913.1 - 0.07 12.4 0.0 0.087 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Ofd1_CTDD PF10637.9 ORY30914.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term DUF2207 PF09972.9 ORY30915.1 - 0.074 11.8 0.1 0.091 11.5 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TrkH PF02386.16 ORY30916.1 - 0.025 13.0 0.0 0.032 12.7 0.0 1.0 1 0 0 1 1 1 0 Cation transport protein RPEL PF02755.15 ORY30916.1 - 0.068 12.9 0.2 0.14 11.9 0.2 1.5 1 0 0 1 1 1 0 RPEL repeat Got1 PF04178.12 ORY30919.1 - 0.0014 19.0 1.8 0.0021 18.5 1.8 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family MFS_1 PF07690.16 ORY30919.1 - 0.0064 15.5 3.7 0.009 15.0 3.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Ion_trans_2 PF07885.16 ORY30919.1 - 0.29 11.1 3.8 0.51 10.3 3.8 1.3 1 0 0 1 1 1 0 Ion channel LRR_8 PF13855.6 ORY30924.1 - 7.8e-09 35.2 3.0 1.1e-05 25.1 1.6 3.1 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY30924.1 - 1.6e-07 31.5 4.2 2.8e-06 27.6 2.6 2.7 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY30924.1 - 0.0007 19.8 6.9 17 6.5 0.0 5.2 4 1 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 ORY30924.1 - 0.12 12.5 4.7 6.7 7.0 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich repeat Asp PF00026.23 ORY30925.1 - 1.3e-61 208.8 4.9 1.5e-61 208.6 4.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY30925.1 - 2.3e-13 50.7 2.6 1.7e-08 34.9 0.1 3.3 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY30925.1 - 6.9e-06 25.9 0.2 2.4e-05 24.1 0.1 2.0 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 ORY30925.1 - 0.00013 22.6 1.3 0.37 11.4 0.0 4.1 3 2 1 4 4 4 2 Aspartyl protease gag-asp_proteas PF13975.6 ORY30925.1 - 0.0078 16.8 0.2 0.6 10.7 0.0 3.2 3 1 0 3 3 3 1 gag-polyprotein putative aspartyl protease HutP PF09021.11 ORY30925.1 - 0.026 14.8 0.0 0.045 14.1 0.0 1.3 1 0 0 1 1 1 0 HutP Kinesin PF00225.23 ORY30926.1 - 2.3e-98 329.2 0.0 2.9e-98 328.9 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY30926.1 - 1.8e-22 79.9 0.0 3.2e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding NUDIX PF00293.28 ORY30927.1 - 1.6e-22 79.9 0.0 3.2e-10 40.1 0.0 2.9 2 1 0 2 2 2 2 NUDIX domain TAD2 PF18521.1 ORY30927.1 - 0.023 14.6 0.0 0.2 11.7 0.0 2.3 2 0 0 2 2 2 0 Transactivation domain 2 NUDIX_2 PF13869.6 ORY30927.1 - 0.097 12.2 0.0 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 Nucleotide hydrolase NIR_SIR_ferr PF03460.17 ORY30927.1 - 0.16 11.8 0.1 4.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain Phosphoesterase PF04185.14 ORY30929.1 - 1.3e-23 83.8 4.4 2.4e-23 82.9 4.4 1.4 1 1 0 1 1 1 1 Phosphoesterase family Mlo PF03094.15 ORY30929.1 - 0.25 9.7 0.0 0.33 9.3 0.0 1.1 1 0 0 1 1 1 0 Mlo family Cation_efflux PF01545.21 ORY30930.1 - 4.5e-31 108.2 9.4 6.3e-31 107.7 9.4 1.2 1 0 0 1 1 1 1 Cation efflux family Cation_efflux PF01545.21 ORY30932.1 - 1.2e-28 100.2 8.4 1.6e-28 99.8 8.4 1.2 1 0 0 1 1 1 1 Cation efflux family RseC_MucC PF04246.12 ORY30932.1 - 0.23 11.4 2.1 0.3 11.0 0.8 1.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Phosphoesterase PF04185.14 ORY30933.1 - 2.5e-19 69.7 2.2 4.7e-19 68.8 2.2 1.4 1 1 0 1 1 1 1 Phosphoesterase family Cation_efflux PF01545.21 ORY30934.1 - 9.8e-39 133.1 6.0 1.2e-38 132.8 6.0 1.1 1 0 0 1 1 1 1 Cation efflux family Plant_vir_prot PF01307.17 ORY30934.1 - 0.096 12.9 0.0 0.27 11.5 0.0 1.8 1 0 0 1 1 1 0 Plant viral movement protein Cation_efflux PF01545.21 ORY30935.1 - 2.8e-37 128.4 6.2 3.6e-37 128.0 6.2 1.1 1 0 0 1 1 1 1 Cation efflux family Homeobox_KN PF05920.11 ORY30936.1 - 3e-16 59.0 0.1 5.5e-16 58.2 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 ORY30936.1 - 1.5e-09 37.6 0.0 2.8e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Homeodomain CENP-B_dimeris PF09026.10 ORY30936.1 - 0.014 15.7 0.5 0.026 14.9 0.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3637 PF12337.8 ORY30936.1 - 0.1 12.9 2.1 0.78 10.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3637) TMEM154 PF15102.6 ORY30936.1 - 3.4 7.6 7.0 1.1 9.1 0.5 2.4 2 0 0 2 2 2 0 TMEM154 protein family CUE PF02845.16 ORY30937.1 - 1.1e-08 34.6 0.0 2.1e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 CUE domain Red1 PF07964.11 ORY30937.1 - 4.4 5.4 11.0 5.9 5.0 11.0 1.1 1 0 0 1 1 1 0 Rec10 / Red1 FAM220 PF15487.6 ORY30937.1 - 5.8 6.5 7.7 10 5.6 7.7 1.3 1 0 0 1 1 1 0 FAM220 family Sec1 PF00995.23 ORY30939.1 - 1e-15 58.0 0.5 1.2e-15 57.7 0.5 1.0 1 0 0 1 1 1 1 Sec1 family Prefoldin PF02996.17 ORY30939.1 - 0.0078 16.1 3.2 0.017 15.0 0.1 2.3 3 0 0 3 3 3 1 Prefoldin subunit V-SNARE PF05008.15 ORY30939.1 - 0.029 14.7 1.3 1 9.8 0.0 2.9 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Sec1 PF00995.23 ORY30940.1 - 1.7e-06 27.6 0.0 2e-06 27.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF3955 PF13127.6 ORY30941.1 - 0.086 12.7 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3955) NADH_dh_m_C1 PF15088.6 ORY30941.1 - 0.099 12.3 0.2 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial tRNA-synt_1 PF00133.22 ORY30942.1 - 1.5e-150 502.3 0.7 4.5e-90 302.6 0.0 5.1 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ORY30942.1 - 1.4e-24 86.8 0.1 2.6e-24 85.9 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ORY30942.1 - 5.1e-13 48.5 0.0 1.1e-06 27.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) TcpQ PF10671.9 ORY30942.1 - 0.014 15.5 0.0 12 6.1 0.0 3.0 3 0 0 3 3 3 0 Toxin co-regulated pilus biosynthesis protein Q tRNA-synt_1e PF01406.19 ORY30942.1 - 0.085 12.2 0.0 0.28 10.5 0.0 1.8 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain AHSP PF09236.10 ORY30942.1 - 0.11 12.9 0.0 0.45 11.0 0.0 2.1 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein UPF0020 PF01170.18 ORY30943.1 - 1.6e-10 41.0 0.0 3.4e-09 36.7 0.0 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 ORY30943.1 - 0.0007 19.4 0.1 0.012 15.3 0.0 2.2 2 0 0 2 2 2 1 DNA methylase Methyltransf_15 PF09445.10 ORY30943.1 - 0.0088 15.6 0.0 0.015 14.9 0.0 1.5 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase N6_Mtase PF02384.16 ORY30943.1 - 0.034 13.4 0.0 0.09 12.0 0.0 1.7 1 1 0 1 1 1 0 N-6 DNA Methylase Sacchrp_dh_C PF16653.5 ORY30944.1 - 1.2e-12 48.5 0.0 3.4e-12 47.0 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 ORY30944.1 - 1.6e-10 41.3 0.1 3.1e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 ORY30944.1 - 0.079 12.3 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 ThiF family DUF4705 PF15788.5 ORY30944.1 - 0.23 11.7 0.8 27 5.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4705) DUF2408 PF10303.9 ORY30945.1 - 1.6e-24 87.0 0.7 6.9e-08 33.1 0.0 4.3 2 1 2 4 4 4 4 Protein of unknown function (DUF2408) PHAT PF09246.10 ORY30945.1 - 0.098 12.5 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 PHAT ABC_tran_CTD PF16326.5 ORY30945.1 - 2.7 8.3 13.4 8.6 6.7 0.4 4.5 4 0 0 4 4 4 0 ABC transporter C-terminal domain FR47 PF08445.10 ORY30947.1 - 3.7e-05 23.6 0.0 0.00018 21.4 0.0 2.1 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 ORY30947.1 - 0.0032 18.2 0.0 0.0066 17.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.10 ORY30947.1 - 0.0069 16.6 0.3 0.043 14.1 0.1 2.4 2 1 0 2 2 2 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acetyltransf_1 PF00583.25 ORY30947.1 - 0.014 15.6 0.0 0.049 13.9 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_1 PF00583.25 ORY30949.1 - 3.3e-05 24.1 0.0 8.1e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY30949.1 - 0.00072 19.5 0.0 0.0045 16.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY30949.1 - 0.0027 18.1 0.0 0.0062 16.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 ORY30949.1 - 0.019 14.9 0.1 0.08 12.9 0.0 2.0 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Acetyltransf_CG PF14542.6 ORY30949.1 - 0.042 14.0 0.0 0.081 13.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PLC-beta_C PF08703.10 ORY30955.1 - 0.047 13.7 1.9 2.3 8.1 1.1 2.2 2 0 0 2 2 2 0 PLC-beta C terminal LidA_Long_CC PF18641.1 ORY30955.1 - 0.21 11.7 1.5 5.2 7.1 0.0 2.2 2 0 0 2 2 2 0 LidA long coiled-coil domain Chromo PF00385.24 ORY30957.1 - 1.1e-14 54.0 1.0 4.7e-14 52.0 1.0 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain BUD22 PF09073.10 ORY30957.1 - 0.00012 21.5 24.6 0.00015 21.2 24.6 1.1 1 0 0 1 1 1 1 BUD22 Chromo_shadow PF01393.19 ORY30957.1 - 0.0023 18.0 0.1 2.6 8.2 0.0 2.5 2 0 0 2 2 2 2 Chromo shadow domain eIF3_subunit PF08597.10 ORY30957.1 - 0.39 10.6 29.9 4 7.3 2.9 3.0 3 0 0 3 3 3 0 Translation initiation factor eIF3 subunit CCDC53 PF10152.9 ORY30957.1 - 0.45 10.9 13.9 2.2 8.7 5.8 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex PBP1_TM PF14812.6 ORY30957.1 - 0.74 10.2 18.4 0.5 10.8 10.3 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Zip PF02535.22 ORY30957.1 - 2.1 7.4 11.3 5.1 6.2 0.2 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter FAM176 PF14851.6 ORY30957.1 - 3.5 7.3 16.6 0.11 12.1 6.8 2.2 2 0 0 2 2 2 0 FAM176 family TFIIF_alpha PF05793.12 ORY30957.1 - 3.6 6.1 31.5 5.8 5.4 31.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4228 PF14009.6 ORY30957.1 - 7.3 6.9 16.5 5.5 7.4 3.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) CRA PF06589.11 ORY30957.1 - 8.7 6.5 12.0 20 5.3 12.0 1.5 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Eapp_C PF10238.9 ORY30957.1 - 9.6 6.3 13.5 13 5.8 9.0 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein Chromo PF00385.24 ORY30958.1 - 4.5e-14 52.1 1.3 7.6e-14 51.4 1.3 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 ORY30958.1 - 0.0067 16.5 0.2 0.15 12.2 0.0 2.8 4 0 0 4 4 4 1 Chromo shadow domain LRR_4 PF12799.7 ORY30959.1 - 0.00024 21.4 11.2 0.47 10.9 0.0 4.4 2 2 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY30959.1 - 0.0024 18.2 3.4 48 5.1 0.1 5.5 5 0 0 5 5 5 0 Leucine Rich Repeat SAM_2 PF07647.17 ORY30959.1 - 0.0073 16.4 0.0 0.34 11.0 0.0 2.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) LRR_8 PF13855.6 ORY30959.1 - 0.034 13.9 2.5 1.3 8.8 0.0 3.4 2 1 1 3 3 3 0 Leucine rich repeat LRR_6 PF13516.6 ORY30959.1 - 0.076 13.1 4.5 5.9 7.2 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich repeat AIP3 PF03915.13 ORY30960.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 YL1 PF05764.13 ORY30961.1 - 0.011 15.9 1.7 0.011 15.9 1.7 2.2 2 0 0 2 2 2 0 YL1 nuclear protein LRR_8 PF13855.6 ORY30962.1 - 1.4e-17 63.2 25.9 7.2e-09 35.3 4.1 4.6 2 2 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 ORY30962.1 - 6.7e-10 39.1 17.7 0.033 14.6 0.7 5.3 2 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY30962.1 - 0.00012 22.1 24.0 3.7 8.5 0.3 7.5 8 0 0 8 8 8 5 Leucine Rich Repeat LRR_6 PF13516.6 ORY30962.1 - 0.0019 18.1 12.4 2.6 8.3 0.3 6.1 7 0 0 7 7 7 2 Leucine Rich repeat F-box-like PF12937.7 ORY30962.1 - 0.054 13.4 0.2 0.18 11.7 0.2 1.9 1 0 0 1 1 1 0 F-box-like Tmemb_14 PF03647.13 ORY30963.1 - 0.0017 19.0 1.1 0.0026 18.4 1.1 1.2 1 0 0 1 1 1 1 Transmembrane proteins 14C LRR_4 PF12799.7 ORY30965.1 - 1e-22 79.8 26.7 0.00019 21.7 0.8 7.1 4 2 0 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY30965.1 - 1e-09 38.0 27.3 4.5e-05 23.1 2.5 5.2 3 2 3 6 6 6 5 Leucine rich repeat FR47 PF08445.10 ORY30965.1 - 0.0027 17.7 0.0 3.7 7.6 0.0 2.8 2 0 0 2 2 2 2 FR47-like protein LRR_6 PF13516.6 ORY30965.1 - 0.0086 16.1 19.5 21 5.5 0.0 8.5 9 0 0 9 9 9 2 Leucine Rich repeat LRR_9 PF14580.6 ORY30965.1 - 0.0092 15.5 11.0 0.54 9.7 3.0 3.6 2 2 1 3 3 3 2 Leucine-rich repeat Metallophos PF00149.28 ORY30966.1 - 6e-17 62.8 0.6 8.1e-17 62.4 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PGA_cap PF09587.10 ORY30966.1 - 0.008 15.6 0.1 0.063 12.7 0.0 2.0 2 0 0 2 2 2 1 Bacterial capsule synthesis protein PGA_cap KptA_kDCL PF18176.1 ORY30966.1 - 0.07 13.0 0.7 0.6 10.0 0.6 2.1 2 0 0 2 2 2 0 KptA in kinetoplastid DICER domain Dicty_REP PF05086.12 ORY30966.1 - 0.076 11.0 7.3 0.12 10.3 7.3 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FSA_C PF10479.9 ORY30966.1 - 5.7 4.9 18.3 8.2 4.4 18.3 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus LRR_6 PF13516.6 ORY30967.1 - 2.7e-18 64.4 11.5 2e-05 24.3 0.1 6.8 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 ORY30967.1 - 1.1e-07 31.4 0.4 2.2 9.1 0.0 6.1 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_4 PF12799.7 ORY30967.1 - 4.4e-07 30.1 4.8 0.0018 18.6 0.2 4.6 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY30967.1 - 0.0029 17.4 8.5 4.4 7.1 0.3 4.8 3 2 1 4 4 4 2 Leucine rich repeat DEC-1_N PF04625.13 ORY30967.1 - 0.91 8.5 3.4 12 4.7 0.1 2.2 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region KAP PF05804.12 ORY30968.1 - 2.6e-182 607.7 36.8 4.6e-141 471.3 21.8 2.0 2 0 0 2 2 2 2 Kinesin-associated protein (KAP) Arm PF00514.23 ORY30968.1 - 0.077 13.1 0.3 12 6.1 0.0 4.3 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Ribosomal_60s PF00428.19 ORY30968.1 - 0.88 10.2 5.4 19 5.9 1.3 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein DNA_pol_A_exo1 PF01612.20 ORY30970.1 - 3.6e-09 36.6 0.0 1e-08 35.1 0.0 1.8 1 0 0 1 1 1 1 3'-5' exonuclease Acetone_carb_G PF08882.11 ORY30970.1 - 0.065 13.4 0.1 0.2 11.8 0.1 1.8 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit Cys_rich_KTR PF14205.6 ORY30970.1 - 1.8 8.4 6.4 37 4.2 6.4 2.5 1 1 0 1 1 1 0 Cysteine-rich KTR RabGAP-TBC PF00566.18 ORY30971.1 - 3.8e-07 30.0 0.6 1e-06 28.6 0.1 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain F-box PF00646.33 ORY30972.1 - 6e-06 26.0 0.4 4.1e-05 23.4 0.0 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY30972.1 - 0.00011 22.1 0.3 0.0004 20.2 0.0 2.1 2 0 0 2 2 2 1 F-box-like Imm70 PF15601.6 ORY30972.1 - 0.03 13.9 0.0 0.076 12.6 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 70 zinc_ribbon_6 PF14599.6 ORY30972.1 - 0.54 10.3 2.0 1.1 9.3 0.8 2.1 2 0 0 2 2 2 0 Zinc-ribbon RRM_1 PF00076.22 ORY30975.1 - 2.5e-17 62.5 0.0 3.2e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GATase_6 PF13522.6 ORY30976.1 - 0.074 13.2 0.0 0.076 13.2 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferase domain Complex1_LYR PF05347.15 ORY30976.1 - 0.13 12.3 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Neurochondrin PF05536.11 ORY30977.1 - 0.011 14.2 2.8 0.18 10.2 0.2 3.2 2 1 1 3 3 3 0 Neurochondrin F-box PF00646.33 ORY30979.1 - 0.0076 16.1 0.1 0.033 14.1 0.0 2.1 2 0 0 2 2 2 1 F-box domain HPD PF05044.12 ORY30979.1 - 0.0089 15.9 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 Homeo-prospero domain F-box-like PF12937.7 ORY30979.1 - 0.067 13.1 0.9 0.19 11.6 0.1 2.3 2 0 0 2 2 2 0 F-box-like KxDL PF10241.9 ORY31113.1 - 0.024 14.9 0.8 0.22 11.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein SPATA1_C PF15743.5 ORY31114.1 - 0.0046 17.1 4.9 0.0068 16.5 4.9 1.2 1 0 0 1 1 1 1 Spermatogenesis-associated C-terminus DUF3015 PF11220.8 ORY31114.1 - 0.016 15.1 1.2 0.036 14.0 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) FlaC_arch PF05377.11 ORY31114.1 - 0.37 11.2 1.7 2.9 8.4 0.1 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4355 PF14265.6 ORY31114.1 - 1.1 9.5 9.3 2 8.7 9.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF2203 PF09969.9 ORY31114.1 - 3.6 8.3 6.1 11 6.7 6.1 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) TMPIT PF07851.13 ORY31114.1 - 3.9 6.6 6.1 6.1 6.0 6.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein RVT_1 PF00078.27 ORY31115.1 - 0.00066 19.3 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-C2H2 PF00096.26 ORY31115.1 - 0.013 15.9 11.0 6.5 7.4 2.0 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type OrsD PF12013.8 ORY31115.1 - 0.083 13.3 6.7 0.72 10.3 1.9 3.1 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 ORY31115.1 - 1.3 10.1 12.0 16 6.7 2.4 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 ORY31115.1 - 3.3 7.4 8.8 3.7 7.2 1.3 2.4 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain DDE_Tnp_4 PF13359.6 ORY31116.1 - 2e-08 34.1 0.0 2.5e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 ORY31116.1 - 0.00019 21.1 0.1 0.018 14.8 0.1 2.4 2 0 0 2 2 2 2 Helix-turn-helix of DDE superfamily endonuclease DNA_ligase_OB PF03120.16 ORY31117.1 - 0.099 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain SEEEED PF14797.6 ORY31118.1 - 0.085 13.0 23.7 0.058 13.5 19.4 2.2 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex Nop14 PF04147.12 ORY31118.1 - 3.7 5.6 11.7 4.2 5.5 11.7 1.1 1 0 0 1 1 1 0 Nop14-like family TrwB_AAD_bind PF10412.9 ORY31119.1 - 0.012 14.6 0.9 0.68 8.8 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain PhoH PF02562.16 ORY31119.1 - 0.089 12.2 0.0 1.6 8.1 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein Hydrolase_3 PF08282.12 ORY31120.1 - 4.8e-51 173.9 0.0 5.6e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 ORY31120.1 - 1.3e-07 31.4 0.0 1.8e-05 24.4 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 ORY31120.1 - 5e-07 30.2 0.0 0.00011 22.6 0.0 2.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY31120.1 - 0.00034 21.1 1.0 1.9 8.8 0.0 3.1 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY31120.1 - 0.019 15.0 0.0 0.099 12.7 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase WD40 PF00400.32 ORY31121.1 - 1.6e-55 183.8 15.1 3.3e-10 40.4 0.1 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY31121.1 - 7.3e-22 77.5 1.7 0.00012 22.3 0.1 5.0 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY31121.1 - 2.3e-08 33.2 4.6 0.00095 17.9 0.0 4.0 2 2 3 5 5 5 2 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY31121.1 - 1.1e-06 28.2 0.3 0.017 14.4 0.0 3.1 2 1 1 3 3 3 2 WD40-like domain Cytochrom_D1 PF02239.16 ORY31121.1 - 0.0003 19.5 0.4 0.059 11.9 0.1 2.4 1 1 0 2 2 2 2 Cytochrome D1 heme domain LisH PF08513.11 ORY31121.1 - 0.00033 20.5 0.1 0.00096 19.0 0.1 1.9 1 0 0 1 1 1 1 LisH DUF1513 PF07433.11 ORY31121.1 - 0.0022 17.2 0.3 0.51 9.4 0.1 3.2 2 2 1 3 3 3 1 Protein of unknown function (DUF1513) Coatomer_WDAD PF04053.14 ORY31121.1 - 0.0046 16.0 0.1 0.63 9.0 0.1 2.5 2 1 0 2 2 2 1 Coatomer WD associated region PQQ_2 PF13360.6 ORY31121.1 - 0.0055 16.3 1.4 0.018 14.6 0.1 2.3 1 1 2 3 3 3 1 PQQ-like domain Ge1_WD40 PF16529.5 ORY31121.1 - 0.061 12.3 2.7 19 4.1 0.8 3.6 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 ORY31121.1 - 0.087 11.9 0.0 4 6.4 0.0 2.2 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain W_rich_C PF07483.11 ORY31121.1 - 0.26 11.5 2.8 4.6 7.5 0.1 3.1 2 1 1 3 3 3 0 Tryptophan-rich Synechocystis species C-terminal domain bZIP_1 PF00170.21 ORY31122.1 - 0.002 18.2 4.5 0.003 17.6 4.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY31122.1 - 0.0022 18.0 3.6 0.003 17.6 3.6 1.2 1 0 0 1 1 1 1 Basic region leucine zipper ECH_1 PF00378.20 ORY31123.1 - 2.4e-40 138.4 0.8 6.4e-40 137.0 0.8 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY31123.1 - 1.2e-23 84.2 0.1 4.9e-23 82.2 0.1 1.6 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Phage_coat PF09063.10 ORY31123.1 - 0.08 13.0 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Phage PP7 coat protein BAR_3 PF16746.5 ORY31123.1 - 0.3 10.7 0.0 0.43 10.3 0.0 1.2 1 0 0 1 1 1 0 BAR domain of APPL family F-box-like PF12937.7 ORY31124.1 - 0.0016 18.3 0.1 0.005 16.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.7 ORY31125.1 - 0.0017 18.2 0.1 0.0048 16.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like Methyltransf_25 PF13649.6 ORY31126.1 - 0.00031 21.4 0.4 0.0019 18.9 0.4 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY31126.1 - 0.0038 17.1 0.0 0.011 15.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY31126.1 - 0.0071 17.0 0.3 0.036 14.7 0.3 2.1 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORY31126.1 - 0.01 15.2 0.3 0.078 12.3 0.3 2.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ank_2 PF12796.7 ORY31127.1 - 5.2e-05 23.8 0.7 0.0006 20.4 0.0 3.0 4 0 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY31127.1 - 0.044 14.4 2.3 1.2 9.8 0.0 3.6 5 0 0 5 5 5 0 Ankyrin repeats (many copies) F-box-like PF12937.7 ORY31127.1 - 0.45 10.4 3.1 0.43 10.5 0.3 2.5 2 0 0 2 2 2 0 F-box-like polyprenyl_synt PF00348.17 ORY31128.1 - 1.3e-59 201.4 0.0 5e-59 199.4 0.0 2.0 1 1 1 2 2 2 1 Polyprenyl synthetase DUF1386 PF07138.11 ORY31128.1 - 0.035 13.4 0.0 0.074 12.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1386) Glyco_hydro_20 PF00728.22 ORY31129.1 - 0.067 12.6 0.4 0.087 12.2 0.4 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain TFIIA PF03153.13 ORY31129.1 - 0.73 9.8 17.0 0.96 9.4 17.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 ORY31130.1 - 2.4e-19 69.7 0.0 3e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 ORY31130.1 - 7.2e-09 34.9 0.0 9.6e-09 34.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 ORY31130.1 - 0.0003 20.5 0.0 0.0005 19.8 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_Tyr PF07714.17 ORY31130.1 - 0.00042 19.7 0.0 0.00055 19.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 ORY31131.1 - 3.5e-45 151.4 20.9 9.5e-09 35.7 0.3 6.5 6 0 0 6 6 6 6 Sel1 repeat TPR_6 PF13174.6 ORY31131.1 - 6.3e-05 23.4 1.2 0.34 11.7 0.1 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat FAD_binding_3 PF01494.19 ORY31131.1 - 0.004 16.5 0.0 0.012 14.9 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain ANAPC3 PF12895.7 ORY31131.1 - 0.12 12.6 1.8 0.82 9.9 0.1 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 ORY31131.1 - 0.14 12.7 7.0 5.3 7.6 0.4 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Rogdi_lz PF10259.9 ORY31132.1 - 1e-25 90.8 0.0 1.1e-25 90.6 0.0 1.1 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein DUF1574 PF07611.11 ORY31132.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) Shisa PF13908.6 ORY31134.1 - 0.033 14.4 0.4 0.063 13.5 0.4 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TMEM132D_C PF15706.5 ORY31134.1 - 0.066 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TMEM51 PF15345.6 ORY31134.1 - 0.072 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 PMP1_2 PF08114.11 ORY31134.1 - 0.077 12.7 0.8 0.17 11.7 0.8 1.5 1 0 0 1 1 1 0 ATPase proteolipid family CD34_antigen PF06365.12 ORY31134.1 - 0.085 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Mid2 PF04478.12 ORY31134.1 - 0.49 10.2 3.9 0.19 11.6 0.7 1.8 1 1 1 2 2 2 0 Mid2 like cell wall stress sensor Dynamitin PF04912.14 ORY31135.1 - 2.2e-23 83.2 4.4 1.8e-21 76.9 4.4 2.1 1 1 0 1 1 1 1 Dynamitin FAD_binding_3 PF01494.19 ORY31136.1 - 4.1e-25 88.8 1.3 2e-12 47.0 0.3 2.9 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ORY31136.1 - 1.3e-08 34.4 1.1 0.0014 17.9 0.1 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY31136.1 - 1.8e-06 28.1 0.1 2.7e-05 24.3 0.0 2.6 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY31136.1 - 4.8e-06 26.4 0.0 0.0027 17.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY31136.1 - 7.9e-06 25.3 0.0 0.0037 16.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 ORY31136.1 - 0.0017 17.9 0.1 0.13 11.9 0.0 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 ORY31136.1 - 0.002 16.9 0.2 0.078 11.7 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 ORY31136.1 - 0.0047 16.1 0.0 0.014 14.6 0.0 1.7 3 0 0 3 3 3 1 FAD binding domain ApbA PF02558.16 ORY31136.1 - 0.0047 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 ORY31136.1 - 0.0053 16.1 0.2 0.092 12.1 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 ORY31136.1 - 0.02 14.9 1.2 1.9 8.4 0.1 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.22 ORY31136.1 - 0.023 13.8 0.1 0.038 13.1 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 ORY31136.1 - 0.027 14.3 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 ORY31136.1 - 0.029 13.2 0.3 7 5.4 0.1 2.8 3 0 0 3 3 3 0 Tryptophan halogenase SE PF08491.10 ORY31136.1 - 0.042 12.9 0.0 0.47 9.5 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Lycopene_cycl PF05834.12 ORY31136.1 - 0.074 12.1 0.0 5 6.1 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 ORY31136.1 - 0.088 13.4 1.1 9.9 6.8 0.1 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Alginate_lyase2 PF08787.11 ORY31137.1 - 9.9e-08 32.1 0.1 4.1e-07 30.1 0.1 1.8 1 1 0 1 1 1 1 Alginate lyase Alginate_lyase2 PF08787.11 ORY31138.1 - 3.5e-10 40.1 0.0 4.3e-10 39.8 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase FlbD PF06289.11 ORY31138.1 - 0.079 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Flagellar and Swarming motility proteins DEC-1_N PF04625.13 ORY31138.1 - 0.47 9.4 3.6 0.5 9.3 3.6 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Ank_2 PF12796.7 ORY31140.1 - 0.12 13.0 0.2 2.3 8.9 0.1 2.4 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 ORY31141.1 - 1.9e-06 28.3 0.9 0.0019 18.7 0.1 3.8 3 1 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY31141.1 - 0.011 16.3 0.1 2.9 8.6 0.0 4.0 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY31141.1 - 0.014 15.7 0.1 36 4.8 0.0 4.0 3 1 1 4 4 4 0 Ankyrin repeats (many copies) F-box-like PF12937.7 ORY31141.1 - 0.022 14.7 0.2 0.064 13.2 0.2 1.8 1 0 0 1 1 1 0 F-box-like Ank_2 PF12796.7 ORY31142.1 - 0.0001 22.8 1.1 2 9.1 0.1 3.7 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY31142.1 - 0.00024 21.3 0.0 0.65 10.8 0.0 4.1 3 0 0 3 3 3 1 Ankyrin repeat F-box-like PF12937.7 ORY31142.1 - 0.014 15.3 2.9 0.051 13.5 0.3 2.8 2 0 0 2 2 2 0 F-box-like Ank_5 PF13857.6 ORY31142.1 - 0.023 15.0 0.8 0.25 11.7 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Baculo_IE-1 PF05290.11 ORY31142.1 - 0.057 13.4 0.4 0.13 12.3 0.4 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Ank_4 PF13637.6 ORY31142.1 - 0.093 13.3 0.9 77 4.0 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeats (many copies) adh_short PF00106.25 ORY31144.1 - 1.3e-47 161.7 0.7 1.5e-46 158.3 0.4 1.9 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY31144.1 - 4.5e-36 124.6 0.1 7.2e-36 123.9 0.1 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY31144.1 - 0.00027 20.9 0.1 0.0006 19.8 0.1 1.5 1 1 0 1 1 1 1 KR domain zf-RING_2 PF13639.6 ORY31145.1 - 5.1e-18 65.1 33.6 2.2e-09 37.5 10.3 4.1 3 0 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.25 ORY31145.1 - 4.2e-17 61.7 31.8 3.9e-09 36.2 9.6 4.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY31145.1 - 1.6e-16 59.8 34.9 1.5e-09 37.5 10.1 3.5 3 0 0 3 3 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY31145.1 - 3.5e-15 55.7 28.6 1e-07 31.8 8.3 3.6 3 0 0 3 3 3 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORY31145.1 - 5.6e-13 48.5 24.8 1.5e-06 27.9 5.0 4.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY31145.1 - 9.6e-11 41.7 38.9 4.5e-06 26.7 10.4 4.9 4 0 0 4 4 4 2 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 ORY31145.1 - 9.4e-10 38.6 22.2 7.3e-05 23.0 6.8 3.2 2 0 0 2 2 2 2 RING-H2 zinc finger domain zf-RING_6 PF14835.6 ORY31145.1 - 1.1e-09 38.0 12.4 3.2e-06 26.9 1.8 3.1 2 0 0 2 2 2 2 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 ORY31145.1 - 4.2e-09 36.2 35.7 3.1e-06 27.0 8.5 3.9 4 0 0 4 4 2 2 zinc-RING finger domain zf-RING_4 PF14570.6 ORY31145.1 - 3.6e-05 23.4 24.7 0.0048 16.7 6.3 4.2 3 2 0 3 3 2 2 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 ORY31145.1 - 4.6e-05 23.2 33.3 0.0046 16.8 9.2 4.0 3 2 2 5 5 4 2 Prokaryotic RING finger family 4 zf-Nse PF11789.8 ORY31145.1 - 0.0043 16.8 17.6 0.071 12.9 3.8 2.7 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 ORY31145.1 - 0.0072 16.3 17.4 0.14 12.2 3.5 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3385 PF11865.8 ORY31145.1 - 0.045 13.6 1.4 0.27 11.1 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) zf-RING_10 PF16685.5 ORY31145.1 - 0.062 13.4 22.3 0.48 10.6 7.2 3.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 MH1 PF03165.16 ORY31145.1 - 0.13 12.5 2.3 0.52 10.5 0.1 2.9 3 0 0 3 3 2 0 MH1 domain Anti-TRAP PF15777.5 ORY31145.1 - 0.28 11.2 0.1 0.28 11.2 0.1 4.8 5 0 0 5 5 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein Rtf2 PF04641.12 ORY31145.1 - 0.42 9.9 4.4 2.5 7.4 0.2 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger DZR PF12773.7 ORY31145.1 - 0.69 10.0 34.6 0.27 11.3 3.6 4.9 4 2 2 6 6 5 0 Double zinc ribbon DnaJ_CXXCXGXG PF00684.19 ORY31145.1 - 0.7 10.3 19.3 0.058 13.8 1.4 3.5 4 0 0 4 4 3 0 DnaJ central domain RIX1 PF08167.12 ORY31145.1 - 1.7 8.3 7.1 1.6 8.4 0.1 3.9 4 2 0 4 4 4 0 rRNA processing/ribosome biogenesis Trm112p PF03966.16 ORY31145.1 - 2 9.0 8.3 6.3 7.5 0.3 4.0 3 1 0 3 3 3 0 Trm112p-like protein FYVE PF01363.21 ORY31145.1 - 5.7 7.1 26.9 4.2 7.6 2.0 4.7 3 2 1 4 4 4 0 FYVE zinc finger zf-MIZ PF02891.20 ORY31145.1 - 9.5 6.1 24.1 7.8 6.3 6.3 3.7 3 0 0 3 3 3 0 MIZ/SP-RING zinc finger Dopey_N PF04118.14 ORY31146.1 - 0.0079 15.3 0.1 1.2 8.1 0.0 2.3 2 0 0 2 2 2 2 Dopey, N-terminal RIH_assoc PF08454.11 ORY31146.1 - 1 9.3 5.2 0.68 9.8 0.2 2.9 2 1 1 3 3 3 0 RyR and IP3R Homology associated TFIIA PF03153.13 ORY31147.1 - 0.12 12.3 11.1 0.17 11.8 11.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPX PF03105.19 ORY31147.1 - 0.15 11.9 8.0 0.21 11.5 8.0 1.2 1 0 0 1 1 1 0 SPX domain DUF4834 PF16118.5 ORY31147.1 - 0.23 12.5 0.1 0.23 12.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 ORY31147.1 - 5.5 6.5 17.0 11 5.6 17.0 1.4 1 0 0 1 1 1 0 Spt20 family BTB PF00651.31 ORY31149.1 - 0.00084 19.5 0.0 0.0021 18.2 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain DUF4097 PF13349.6 ORY31150.1 - 8e-07 28.7 0.0 1.9e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Putative adhesin Abhydro_lipase PF04083.16 ORY31151.1 - 3.4e-19 68.2 0.0 7.1e-19 67.2 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 ORY31151.1 - 2e-12 47.3 0.2 1.3e-11 44.6 0.1 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY31151.1 - 6.3e-07 28.9 0.0 1.1e-05 24.8 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY31151.1 - 1.4e-05 25.9 0.1 2.9e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Glyco_hydro_18 PF00704.28 ORY31152.1 - 0.033 13.9 0.0 0.038 13.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 JHBP PF06585.11 ORY31154.1 - 0.2 10.8 0.1 0.28 10.3 0.1 1.2 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) BTB PF00651.31 ORY31155.1 - 1.1e-06 28.9 0.0 2.3e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Pirin_C PF05726.13 ORY31156.1 - 9e-25 87.0 0.0 4.2e-24 84.9 0.0 2.0 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin PF02678.16 ORY31156.1 - 7e-09 35.6 0.2 1.6e-08 34.5 0.2 1.6 1 0 0 1 1 1 1 Pirin TcpQ PF10671.9 ORY31157.1 - 0.082 13.0 0.1 9.8 6.4 0.0 2.0 1 1 1 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q Glyco_hydro_26 PF02156.15 ORY31158.1 - 0.0001 21.9 1.7 0.00012 21.6 1.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 DnaJ PF00226.31 ORY31161.1 - 1.7e-20 72.9 0.1 4.7e-20 71.5 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 ORY31161.1 - 1.9e-17 63.4 0.8 3.3e-17 62.7 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DUF1962 PF09227.10 ORY31162.1 - 3 8.3 24.3 0.56 10.6 2.5 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1962) AAA_16 PF13191.6 ORY31165.1 - 1.2e-11 45.3 0.1 2.4e-05 24.8 0.0 2.9 3 0 0 3 3 3 2 AAA ATPase domain NACHT PF05729.12 ORY31165.1 - 1.3e-05 25.2 0.2 0.0029 17.6 0.0 3.5 4 0 0 4 4 4 1 NACHT domain TPR_7 PF13176.6 ORY31165.1 - 0.0014 18.5 2.4 0.059 13.4 0.4 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY31165.1 - 0.0035 17.3 0.1 0.29 11.4 0.2 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY31165.1 - 0.0065 16.2 0.6 0.11 12.3 0.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY31165.1 - 0.007 16.6 0.4 0.13 12.6 0.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.6 ORY31165.1 - 0.033 14.4 0.5 0.25 11.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain Thioredoxin_13 PF18401.1 ORY31165.1 - 0.051 13.5 0.4 0.23 11.4 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like domain TPR_8 PF13181.6 ORY31165.1 - 0.069 13.4 1.6 1.8 9.0 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY31165.1 - 0.13 12.1 0.2 3.9 7.5 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Sulfotransfer_4 PF17784.1 ORY31165.1 - 0.17 11.7 0.0 0.44 10.3 0.0 1.6 1 0 0 1 1 1 0 Sulfotransferase domain Alginate_lyase2 PF08787.11 ORY31166.1 - 1.7e-18 67.4 0.0 2.4e-17 63.6 0.0 2.0 1 1 0 1 1 1 1 Alginate lyase RabGAP-TBC PF00566.18 ORY31167.1 - 9.7e-17 61.3 1.5 2e-16 60.3 1.5 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Sec5 PF15469.6 ORY31167.1 - 0.04 13.7 3.7 0.29 10.9 1.3 2.4 2 0 0 2 2 2 0 Exocyst complex component Sec5 Kelch_6 PF13964.6 ORY31167.1 - 0.048 14.0 0.0 3.8 7.9 0.0 2.9 2 0 0 2 2 2 0 Kelch motif WD40 PF00400.32 ORY31167.1 - 0.23 12.4 2.6 1.8 9.6 0.0 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF641 PF04859.12 ORY31167.1 - 0.27 11.6 3.3 0.7 10.2 3.3 1.6 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Tam41_Mmp37 PF09139.11 ORY31168.1 - 1.3e-101 340.2 0.0 1.5e-101 340.1 0.0 1.0 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial S1 PF00575.23 ORY31169.1 - 5.1e-73 241.4 51.1 1.1e-12 48.1 0.7 15.4 15 1 0 15 15 15 12 S1 RNA binding domain Suf PF05843.14 ORY31169.1 - 8.3e-07 29.3 0.0 8.3e-07 29.3 0.0 3.7 3 1 1 4 4 4 2 Suppressor of forked protein (Suf) S1_2 PF13509.6 ORY31169.1 - 0.0017 18.4 1.7 1.2 9.2 0.1 5.0 6 0 0 6 6 6 1 S1 domain RNase_II_C_S1 PF18614.1 ORY31169.1 - 0.002 18.0 13.2 4.9 7.2 0.7 8.0 9 0 0 9 9 9 1 RNase II-type exonuclease C-terminal S1 domain TPR_14 PF13428.6 ORY31169.1 - 0.0029 18.3 1.3 42 5.3 0.0 5.5 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY31169.1 - 0.069 13.2 0.1 1 9.5 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY31169.1 - 0.11 12.7 0.1 22 5.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PI3K_1B_p101 PF10486.9 ORY31169.1 - 3.8 5.2 17.2 6.6 4.4 17.2 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Cu-oxidase PF00394.22 ORY31170.1 - 4.8e-40 137.3 4.6 1.5e-39 135.7 0.4 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORY31170.1 - 2.8e-36 124.1 12.7 2.3e-33 114.7 1.8 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY31170.1 - 3.1e-16 59.4 7.5 2.4e-10 40.3 0.2 4.2 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORY31171.1 - 9.1e-36 122.5 13.3 9.8e-36 122.4 4.0 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY31171.1 - 7.2e-25 87.3 16.3 3e-20 72.4 6.2 3.9 2 2 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 ORY31171.1 - 7.4e-24 84.7 10.0 1.9e-23 83.3 1.1 3.7 3 2 1 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 ORY31172.1 - 1.5e-37 129.2 3.5 1.3e-36 126.1 0.1 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORY31172.1 - 4.2e-36 123.6 8.7 2.9e-35 120.8 1.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY31172.1 - 3.4e-25 88.4 17.2 2.5e-18 66.1 7.4 4.8 3 2 0 3 3 3 3 Multicopper oxidase DnaJ_C PF01556.18 ORY31173.1 - 2e-37 128.5 1.6 2.7e-37 128.1 1.6 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORY31173.1 - 2.2e-21 75.7 2.9 5.2e-21 74.5 2.9 1.7 1 0 0 1 1 1 1 DnaJ domain BCIP PF13862.6 ORY31174.1 - 3.9e-58 196.6 3.1 3.9e-58 196.6 3.1 1.8 2 0 0 2 2 2 1 p21-C-terminal region-binding protein Transmemb_17 PF09799.9 ORY31175.1 - 2.6e-14 53.7 2.0 5e-14 52.8 2.0 1.5 1 0 0 1 1 1 1 Predicted membrane protein MutS_V PF00488.21 ORY31176.1 - 7.8e-42 143.4 0.6 1.8e-41 142.3 0.6 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORY31176.1 - 1.4e-29 103.6 1.4 2.3e-29 103.0 1.4 1.3 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 ORY31176.1 - 2.5e-09 37.4 0.0 5.4e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 ORY31176.1 - 5.6e-06 26.7 0.1 1.3e-05 25.5 0.1 1.7 1 0 0 1 1 1 1 MutS domain II Pirin PF02678.16 ORY31179.1 - 9.4e-17 61.0 0.0 1.6e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Pirin Cas1_AcylT PF07779.12 ORY31180.1 - 6.1e-113 378.2 18.1 9.5e-113 377.6 18.1 1.2 1 0 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.6 ORY31180.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Ank_2 PF12796.7 ORY31181.1 - 0.0077 16.8 1.6 0.69 10.5 0.0 3.4 2 1 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_2 PF12796.7 ORY31182.1 - 0.0001 22.8 1.1 2 9.1 0.1 3.7 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY31182.1 - 0.00025 21.2 0.0 0.65 10.8 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat F-box-like PF12937.7 ORY31182.1 - 0.015 15.2 2.4 0.069 13.1 0.2 2.8 2 0 0 2 2 2 0 F-box-like Ank_5 PF13857.6 ORY31182.1 - 0.023 15.0 0.8 0.25 11.7 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Baculo_IE-1 PF05290.11 ORY31182.1 - 0.056 13.4 0.4 0.13 12.3 0.4 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Ank_4 PF13637.6 ORY31182.1 - 0.089 13.4 0.9 77 4.0 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY31183.1 - 6.6e-06 26.6 0.9 0.0077 16.8 0.1 3.9 3 1 1 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY31183.1 - 0.0049 17.4 0.1 1.2 9.8 0.0 3.9 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY31183.1 - 0.0067 16.7 0.1 36 4.8 0.0 4.0 3 1 1 4 4 4 1 Ankyrin repeats (many copies) F-box-like PF12937.7 ORY31183.1 - 0.021 14.7 0.2 0.064 13.2 0.2 1.8 1 0 0 1 1 1 0 F-box-like DUF3447 PF11929.8 ORY31183.1 - 0.23 11.4 4.1 0.9 9.5 1.3 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3447) LAMTOR5 PF16672.5 ORY31184.1 - 1.9e-13 50.2 0.1 5.6e-13 48.6 0.1 1.8 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Ank_2 PF12796.7 ORY31184.1 - 0.00024 21.6 4.0 0.38 11.4 0.0 4.3 5 1 0 5 5 5 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY31184.1 - 0.085 13.2 0.6 10 6.6 0.0 3.6 2 1 1 3 3 3 0 Ankyrin repeats (many copies) DUF3894 PF13033.6 ORY31184.1 - 0.094 12.8 0.1 0.5 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3894) CRISPR_Cas9_WED PF18061.1 ORY31184.1 - 0.1 12.7 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 CRISPR-Cas9 WED domain CD225 PF04505.12 ORY31185.1 - 3.1e-09 36.8 1.8 4.1e-09 36.4 1.8 1.1 1 0 0 1 1 1 1 Interferon-induced transmembrane protein VirB3 PF05101.13 ORY31185.1 - 0.28 11.5 0.1 0.28 11.5 0.1 2.0 1 1 1 2 2 2 0 Type IV secretory pathway, VirB3-like protein Glyco_hydro_18 PF00704.28 ORY31186.1 - 1.3e-09 38.3 3.4 2.5e-09 37.3 3.4 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 ETRAMP PF09716.10 ORY31186.1 - 0.012 15.7 0.2 0.023 14.8 0.2 1.4 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF3357 PF11837.8 ORY31186.1 - 0.08 13.4 0.4 0.16 12.4 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF202 PF02656.15 ORY31187.1 - 6.7e-16 58.5 3.3 1.7e-15 57.2 1.3 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF202) MMR_HSR1 PF01926.23 ORY31188.1 - 5.2e-06 26.5 0.0 1.2e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Smg8_Smg9 PF10220.9 ORY31188.1 - 0.0058 15.0 0.0 0.0058 15.0 0.0 1.9 3 0 0 3 3 3 1 Smg8_Smg9 RsgA_GTPase PF03193.16 ORY31188.1 - 0.0062 16.5 0.1 0.011 15.6 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 ORY31188.1 - 0.014 15.9 0.0 0.034 14.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Dynamin_N PF00350.23 ORY31188.1 - 0.082 13.0 0.3 0.082 13.0 0.3 2.0 3 0 0 3 3 3 0 Dynamin family Zip PF02535.22 ORY31188.1 - 1.2 8.3 4.0 7.5 5.7 0.0 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter BUD22 PF09073.10 ORY31188.1 - 1.6 8.0 16.7 0.012 15.0 4.7 2.1 2 0 0 2 2 2 0 BUD22 DUF2052 PF09747.9 ORY31188.1 - 2.1 8.4 12.9 0.076 13.1 5.5 1.9 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Spidroin_MaSp PF11260.8 ORY31189.1 - 0.059 13.7 1.3 0.18 12.1 0.9 1.8 2 0 0 2 2 2 0 Major ampullate spidroin 1 and 2 HSP20 PF00011.21 ORY31190.1 - 1.5e-12 47.5 0.1 2.1e-12 47.1 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORY31190.1 - 9.2e-07 28.3 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Alkyl_sulf_C PF14864.6 ORY31190.1 - 0.046 14.0 0.0 0.11 12.7 0.0 1.7 1 1 1 2 2 2 0 Alkyl sulfatase C-terminal RRM_1 PF00076.22 ORY31191.1 - 0.37 10.6 1.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fz PF01392.22 ORY31192.1 - 7.3e-05 23.3 3.2 0.00017 22.2 3.2 1.6 1 0 0 1 1 1 1 Fz domain Phage_holin_3_1 PF05106.12 ORY31192.1 - 0.11 12.9 1.1 2.9 8.4 0.0 2.7 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) zf-CCCH_2 PF14608.6 ORY31193.1 - 4.2e-07 30.2 38.8 0.00016 22.0 10.2 3.4 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger Zip PF02535.22 ORY31193.1 - 1.6 7.9 6.2 3.7 6.7 6.2 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIA PF03153.13 ORY31193.1 - 8.4 6.3 43.4 8.7 6.2 4.9 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Glyco_trans_1_2 PF13524.6 ORY31194.1 - 0.00058 20.2 0.8 0.0031 17.9 0.1 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 DNA_pol_A_exo1 PF01612.20 ORY31195.1 - 8.8e-08 32.1 0.0 3.8e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 3'-5' exonuclease Glyco_trans_1_2 PF13524.6 ORY31196.1 - 0.00036 20.9 0.0 0.00072 19.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Astro_capsid_p PF12226.8 ORY31197.1 - 0.36 9.9 9.2 1 8.4 9.2 1.7 1 0 0 1 1 1 0 Turkey astrovirus capsid protein zf-RING_4 PF14570.6 ORY31198.1 - 1e-21 76.5 13.1 1e-21 76.5 13.1 2.1 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 ORY31198.1 - 8.6e-07 28.7 8.6 8.6e-07 28.7 8.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 ORY31198.1 - 1.7e-06 27.8 0.4 1.7e-05 24.5 0.4 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prok-RING_4 PF14447.6 ORY31198.1 - 4.8e-05 23.1 13.7 0.0029 17.4 5.2 3.2 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 ORY31198.1 - 6.2e-05 23.2 10.7 6.2e-05 23.2 10.7 2.1 2 0 0 2 2 2 1 Ring finger domain zf-UDP PF14569.6 ORY31198.1 - 0.00038 20.5 4.4 0.00038 20.5 4.4 2.2 2 0 0 2 2 2 1 Zinc-binding RING-finger Baculo_IE-1 PF05290.11 ORY31198.1 - 0.0025 17.8 5.4 0.0025 17.8 5.4 2.1 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.12 ORY31198.1 - 0.0093 15.4 2.5 0.014 14.7 2.5 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger DUF1154 PF06631.11 ORY31198.1 - 0.089 12.8 0.3 0.19 11.8 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) NPDC1 PF06809.11 ORY31198.1 - 0.15 11.1 0.5 0.24 10.4 0.5 1.2 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) zf-C3HC4_2 PF13923.6 ORY31198.1 - 0.26 11.2 20.5 0.064 13.1 11.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY31198.1 - 0.68 9.8 19.9 0.2 11.5 10.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY31198.1 - 1 9.4 18.2 0.86 9.7 5.9 3.3 3 0 0 3 3 3 0 RING-type zinc-finger zf-RING_10 PF16685.5 ORY31198.1 - 2.2 8.5 12.1 4.7 7.4 5.3 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 DUF4451 PF14616.6 ORY31198.1 - 2.5 8.3 8.2 3.9 7.7 1.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4451) Spc7_N PF15402.6 ORY31198.1 - 6.5 4.9 5.3 9.2 4.4 5.3 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 zf-RING_5 PF14634.6 ORY31198.1 - 7.7 6.6 17.8 4.3 7.4 9.2 2.6 2 0 0 2 2 2 0 zinc-RING finger domain SNF2_N PF00176.23 ORY31199.1 - 7e-77 258.5 0.1 1.2e-76 257.8 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY31199.1 - 3.9e-16 59.4 0.0 1.2e-15 57.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 ORY31199.1 - 0.00091 19.0 0.9 0.00091 19.0 0.9 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY31199.1 - 0.0012 18.8 5.3 0.0027 17.6 5.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.15 ORY31199.1 - 0.0051 16.8 0.2 1.1 9.2 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 ORY31199.1 - 0.0063 16.8 1.0 0.018 15.4 1.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORY31199.1 - 0.008 16.0 1.0 0.02 14.8 1.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY31199.1 - 0.038 13.9 3.6 0.14 12.1 3.6 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 ERCC3_RAD25_C PF16203.5 ORY31199.1 - 0.074 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Csd3_N PF18059.1 ORY31199.1 - 0.16 12.5 0.1 11 6.6 0.0 2.5 2 0 0 2 2 2 0 Csd3 N-terminal zf-rbx1 PF12678.7 ORY31199.1 - 0.61 10.4 3.5 1.5 9.2 3.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain IBR PF01485.21 ORY31199.1 - 4 7.7 6.7 1.1 9.5 3.3 1.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Pkinase PF00069.25 ORY31200.1 - 1.1e-47 162.7 1.2 1e-24 87.4 0.3 2.7 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY31200.1 - 2.3e-23 82.8 0.8 2.7e-13 49.8 0.2 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Voltage_CLC PF00654.20 ORY31201.1 - 8.8e-74 248.9 28.0 1.2e-73 248.4 25.4 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 ORY31201.1 - 0.0002 21.8 0.1 0.0011 19.4 0.0 2.3 2 0 0 2 2 2 1 CBS domain 7tm_1 PF00001.21 ORY31348.1 - 0.0063 15.9 12.7 0.03 13.6 11.7 2.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) HET PF06985.11 ORY31349.1 - 6.7e-05 23.3 3.2 0.00084 19.7 3.2 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SDA1 PF05285.12 ORY31349.1 - 1.6 8.1 19.9 2.4 7.5 19.9 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 ORY31349.1 - 3.3 6.9 13.4 6.4 6.0 13.4 1.4 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 ORY31349.1 - 5.4 5.1 18.3 7.7 4.6 18.3 1.1 1 0 0 1 1 1 0 Nop14-like family Pur_DNA_glyco PF02245.16 ORY31350.1 - 0.12 11.8 1.6 0.31 10.5 0.3 2.0 2 0 0 2 2 2 0 Methylpurine-DNA glycosylase (MPG) MFS_1 PF07690.16 ORY31351.1 - 7.6e-13 48.1 16.8 7.6e-13 48.1 16.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GPR_Gpa2_C PF11970.8 ORY31351.1 - 0.7 10.0 4.0 1.9 8.6 0.8 2.9 3 1 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term DDE_Tnp_4 PF13359.6 ORY31451.1 - 0.0013 18.5 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Syndecan PF01034.20 ORY31452.1 - 0.32 10.9 2.4 19 5.2 0.1 2.6 2 0 0 2 2 2 0 Syndecan domain CLASP_N PF12348.8 ORY31487.1 - 1.4e-09 37.9 0.2 2e-08 34.1 0.2 2.1 1 1 0 1 1 1 1 CLASP N terminal Cwf_Cwc_15 PF04889.12 ORY31487.1 - 0.36 10.5 3.8 0.18 11.5 1.4 1.7 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein zf-H2C2_2 PF13465.6 ORY31488.1 - 3.4e-30 103.1 33.6 6.5e-09 35.8 1.3 6.2 6 0 0 6 6 6 6 Zinc-finger double domain zf-C2H2 PF00096.26 ORY31488.1 - 7.4e-26 89.1 30.2 0.00022 21.5 0.1 6.2 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY31488.1 - 3.4e-16 58.6 32.0 0.0054 17.5 0.7 6.3 6 0 0 6 6 6 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY31488.1 - 2.9e-15 56.1 16.2 0.016 15.5 0.0 6.5 6 1 0 6 6 6 6 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY31488.1 - 3.2e-08 33.7 20.2 2.6 8.5 0.1 6.3 6 0 0 6 6 6 4 Zinc-finger of C2H2 type DUF3268 PF11672.8 ORY31488.1 - 0.015 15.6 3.5 0.25 11.7 0.1 2.5 2 1 1 3 3 3 0 zinc-finger-containing domain zf-LYAR PF08790.11 ORY31488.1 - 0.024 14.5 3.4 2.1 8.3 0.0 3.8 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger C1_4 PF07975.12 ORY31488.1 - 0.042 14.1 14.0 0.062 13.5 0.9 3.5 2 1 0 3 3 3 0 TFIIH C1-like domain zf-C2H2_6 PF13912.6 ORY31488.1 - 0.14 12.2 23.4 0.49 10.5 0.1 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger C1_1 PF00130.22 ORY31488.1 - 0.17 11.8 17.5 2.2 8.2 3.0 4.7 3 2 2 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C4 PF00105.18 ORY31488.1 - 3.1 8.3 10.2 16 6.0 0.2 4.1 1 1 3 4 4 4 0 Zinc finger, C4 type (two domains) Kazal_2 PF07648.15 ORY31488.1 - 3.3 7.9 8.0 4.5 7.5 0.6 3.4 4 0 0 4 4 4 0 Kazal-type serine protease inhibitor domain zf-C2H2_2 PF12756.7 ORY31488.1 - 5.4 7.4 22.4 8.7 6.7 0.1 5.1 1 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-H2C2_5 PF13909.6 ORY31488.1 - 6 6.7 27.6 3.3 7.6 0.1 5.8 6 1 0 6 6 6 0 C2H2-type zinc-finger domain Fungal_trans PF04082.18 ORY31489.1 - 0.0025 16.9 0.5 0.0059 15.7 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY31489.1 - 0.043 13.9 7.7 0.085 13.0 7.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF563 PF04577.14 ORY31490.1 - 5.7e-19 69.1 5.2 1.3e-11 45.0 0.3 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF563) TPR_14 PF13428.6 ORY31490.1 - 3.2e-05 24.4 0.0 0.61 11.1 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY31490.1 - 0.00047 20.1 0.1 0.06 13.5 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY31490.1 - 0.0034 17.6 0.5 2.1 8.6 0.0 2.8 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 ORY31490.1 - 0.042 14.4 0.0 7.6 7.1 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY31490.1 - 0.061 14.0 0.2 46 4.9 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Amino_oxidase PF01593.24 ORY31491.1 - 1.5e-34 120.0 0.0 1.8e-34 119.9 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY31491.1 - 3.6e-07 30.3 0.0 8.7e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY31491.1 - 0.0027 17.4 0.0 0.085 12.4 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 ORY31491.1 - 0.86 8.6 2.2 4.2 6.3 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A W2 PF02020.18 ORY31492.1 - 7.2e-23 80.5 2.0 4.7e-22 77.9 2.0 2.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 ORY31492.1 - 8.9e-11 41.1 16.1 0.00012 21.6 3.7 3.4 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 ORY31492.1 - 7.9e-10 38.7 0.0 2e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 ORY31492.1 - 5.7e-05 23.5 0.1 0.0001 22.7 0.1 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 ORY31492.1 - 0.00012 21.8 5.0 0.00012 21.8 5.0 2.9 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 ORY31492.1 - 0.00082 18.4 0.3 0.0015 17.6 0.3 1.4 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 ORY31492.1 - 0.0037 15.5 0.7 0.007 14.6 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) DTW PF03942.15 ORY31493.1 - 7.1e-18 65.0 0.0 1.2e-17 64.3 0.0 1.3 1 1 0 1 1 1 1 DTW domain ATP-synt_G PF04718.15 ORY31494.1 - 4.3e-17 62.8 0.2 5e-17 62.6 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit Pkinase PF00069.25 ORY31496.1 - 1.4e-53 182.0 0.0 3.5e-53 180.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY31496.1 - 1.7e-30 106.2 0.0 8.3e-30 103.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY31496.1 - 0.0024 17.3 0.1 0.007 15.7 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY31496.1 - 0.01 14.6 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase adh_short PF00106.25 ORY31497.1 - 3.8e-34 117.8 0.1 7.1e-32 110.5 0.1 2.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY31497.1 - 1.5e-22 80.3 0.1 3.1e-20 72.7 0.1 2.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY31497.1 - 1.5e-07 31.5 0.0 2.8e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY31497.1 - 5e-05 22.9 0.8 0.00016 21.3 0.8 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY31497.1 - 0.0006 19.3 0.1 0.0011 18.5 0.1 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase PAS_9 PF13426.7 ORY31500.1 - 1.2e-07 31.9 0.0 1.4e-05 25.2 0.0 2.8 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 ORY31500.1 - 0.0022 18.0 0.0 0.0053 16.8 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 ORY31500.1 - 0.0025 17.8 0.0 0.021 14.8 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.12 ORY31500.1 - 0.11 12.7 0.0 1.6 9.1 0.0 2.5 2 0 0 2 2 2 0 PAS fold Orf78 PF06024.12 ORY31500.1 - 1.6 9.1 5.2 10 6.5 0.4 2.9 3 0 0 3 3 3 0 Orf78 (ac78) Glyco_hydro_15 PF00723.21 ORY31501.1 - 4.3e-41 141.1 1.9 3.2e-40 138.3 1.9 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 CoA_trans PF01144.23 ORY31501.1 - 0.11 11.8 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Coenzyme A transferase zf-H2C2_2 PF13465.6 ORY31502.1 - 1.6e-22 78.9 22.6 1.5e-06 28.3 1.0 4.7 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 ORY31502.1 - 4.9e-18 64.5 22.6 0.00012 22.3 2.0 4.2 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY31502.1 - 3.5e-14 52.3 21.9 0.00042 20.9 1.6 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 ORY31502.1 - 2e-06 28.0 8.3 0.045 14.2 0.0 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY31502.1 - 1e-05 25.6 6.0 0.0089 16.3 0.3 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY31502.1 - 0.00039 20.3 0.0 0.00039 20.3 0.0 4.3 5 1 0 5 5 5 2 C2H2-type zinc finger GAGA PF09237.11 ORY31502.1 - 0.00066 19.4 5.9 0.082 12.7 0.4 2.6 1 1 2 3 3 3 2 GAGA factor zf-C2HE PF16278.5 ORY31502.1 - 0.0011 19.4 11.1 0.037 14.5 0.2 3.2 2 1 1 3 3 3 2 C2HE / C2H2 / C2HC zinc-binding finger zinc_ribbon_15 PF17032.5 ORY31502.1 - 0.011 16.4 2.4 0.36 11.6 0.1 2.4 1 1 1 2 2 2 0 zinc-ribbon family zf-Sec23_Sec24 PF04810.15 ORY31502.1 - 0.043 13.9 2.6 0.59 10.2 0.1 2.9 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Zn-ribbon_8 PF09723.10 ORY31502.1 - 1.9 8.6 7.9 16 5.7 1.2 3.0 2 2 1 3 3 3 0 Zinc ribbon domain DUF629 PF04780.12 ORY31502.1 - 5.9 5.3 8.9 2.2 6.7 0.4 3.0 1 1 3 4 4 4 0 Protein of unknown function (DUF629) zf-C2H2 PF00096.26 ORY31503.1 - 1.2e-07 31.8 9.3 0.0003 21.1 2.8 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY31503.1 - 4.1e-06 27.2 6.9 0.0057 17.4 1.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY31503.1 - 0.00041 20.7 6.0 0.24 11.9 0.9 2.5 2 0 0 2 2 2 2 Zinc-finger double domain zf-met PF12874.7 ORY31503.1 - 0.0044 17.4 2.5 0.42 11.1 0.4 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type Elf1 PF05129.13 ORY31503.1 - 0.069 13.2 1.4 0.12 12.4 1.4 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-C2H2_8 PF15909.5 ORY31503.1 - 0.076 13.3 2.6 0.14 12.4 2.6 1.5 1 0 0 1 1 1 0 C2H2-type zinc ribbon BolA PF01722.18 ORY31503.1 - 0.14 12.5 0.7 0.51 10.7 0.1 2.1 1 1 1 2 2 2 0 BolA-like protein zf-C2H2_6 PF13912.6 ORY31503.1 - 0.16 12.0 3.5 1.5 8.9 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY31503.1 - 0.37 11.1 3.4 0.61 10.4 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding WD40 PF00400.32 ORY31504.1 - 1.4e-13 51.1 11.0 0.37 11.7 0.0 7.0 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY31504.1 - 0.00024 21.3 0.0 1.3 9.4 0.0 4.2 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Mcl1_mid PF12341.8 ORY31504.1 - 0.015 14.7 0.0 0.69 9.2 0.0 2.5 1 1 1 2 2 2 0 Minichromosome loss protein, Mcl1, middle region Rap_GAP PF02145.15 ORY31505.1 - 6.1e-59 198.7 0.0 8e-59 198.3 0.0 1.1 1 0 0 1 1 1 1 Rap/ran-GAP FAD_binding_3 PF01494.19 ORY31506.1 - 8.2e-28 97.7 0.1 1.2e-26 93.8 0.1 2.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY31506.1 - 8.8e-13 48.1 1.1 2.4e-06 27.0 0.1 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY31506.1 - 3.5e-09 36.7 0.6 0.0013 18.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY31506.1 - 1.5e-08 33.8 2.4 1.3e-05 24.1 0.2 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 ORY31506.1 - 6.5e-07 29.5 0.1 4.3e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORY31506.1 - 3.2e-06 26.6 2.6 0.0071 15.6 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY31506.1 - 1.6e-05 24.2 1.0 0.0062 15.6 0.0 2.3 2 1 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.22 ORY31506.1 - 1.8e-05 24.0 1.5 3.3e-05 23.1 0.2 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 ORY31506.1 - 4.5e-05 23.9 1.9 0.14 12.8 0.1 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY31506.1 - 5.7e-05 22.4 1.4 8.7e-05 21.8 0.4 1.8 3 0 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.6 ORY31506.1 - 0.0002 21.4 0.1 0.89 9.5 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding SE PF08491.10 ORY31506.1 - 0.00046 19.3 0.0 0.067 12.2 0.0 2.4 3 0 0 3 3 3 1 Squalene epoxidase Trp_halogenase PF04820.14 ORY31506.1 - 0.0016 17.3 1.6 0.4 9.5 0.3 2.3 2 0 0 2 2 2 2 Tryptophan halogenase 3HCDH_N PF02737.18 ORY31506.1 - 0.0021 18.0 0.0 0.015 15.2 0.1 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 ORY31506.1 - 0.013 15.2 0.1 0.034 13.8 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 ORY31506.1 - 0.026 13.9 0.3 0.026 13.9 0.3 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ORY31506.1 - 0.049 12.9 0.2 0.31 10.3 0.1 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 ORY31506.1 - 0.054 12.8 0.2 0.92 8.7 0.1 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase cNMP_binding PF00027.29 ORY31510.1 - 3.5e-13 49.4 0.0 6.3e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 ORY31510.1 - 7.1e-08 32.1 0.0 1.1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 STAS domain Sec2p PF06428.11 ORY31513.1 - 2.7e-12 46.5 10.1 2.7e-12 46.5 10.1 2.1 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p Spc7 PF08317.11 ORY31513.1 - 0.0046 15.9 12.5 0.0046 15.9 12.5 2.2 1 1 1 2 2 2 1 Spc7 kinetochore protein HeLo PF14479.6 ORY31513.1 - 0.048 13.5 8.8 0.095 12.5 8.3 1.8 1 1 0 1 1 1 0 Prion-inhibition and propagation FlaC_arch PF05377.11 ORY31513.1 - 0.48 10.9 2.9 1.7 9.1 2.3 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) KELK PF15796.5 ORY31513.1 - 0.91 10.0 12.7 1.6 9.2 6.4 2.5 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PKI PF02827.16 ORY31513.1 - 1.1 9.5 5.6 0.59 10.4 2.4 2.3 2 0 0 2 2 2 0 cAMP-dependent protein kinase inhibitor PIEZO PF15917.5 ORY31513.1 - 2.1 7.8 6.9 0.14 11.6 1.6 1.7 2 0 0 2 2 2 0 Piezo DUF1664 PF07889.12 ORY31513.1 - 2.4 8.2 9.3 2.6 8.1 1.1 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 ORY31513.1 - 3.1 8.0 16.4 5.7 7.2 2.6 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding HAUS-augmin3 PF14932.6 ORY31513.1 - 5.3 6.5 16.0 1.7 8.2 10.5 2.4 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 zf-C2H2 PF00096.26 ORY31514.1 - 1.2e-06 28.7 10.3 0.0016 18.8 1.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY31514.1 - 2.8e-06 27.5 0.8 2.8e-06 27.5 0.8 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY31514.1 - 0.00087 19.9 7.8 0.069 14.0 1.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY31514.1 - 0.001 19.3 2.5 0.002 18.4 2.5 1.4 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 ORY31514.1 - 0.12 12.5 1.8 0.16 12.1 1.8 1.3 1 1 0 1 1 1 0 Aberrant zinc-finger zf-3CxxC_2 PF17180.4 ORY31514.1 - 1.2 10.0 4.7 3.3 8.5 4.7 1.7 1 1 0 1 1 1 0 Zinc-binding domain NYD-SP28_assoc PF14775.6 ORY31515.1 - 0.47 10.6 7.9 8.1 6.6 5.0 3.0 2 0 0 2 2 2 0 Sperm tail C-terminal domain Atg14 PF10186.9 ORY31515.1 - 2.6 7.0 10.2 0.19 10.8 5.1 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 ORY31515.1 - 3.8 8.0 22.3 98 3.5 0.0 3.0 2 1 0 2 2 2 0 Apg6 coiled-coil region TraW_N PF12477.8 ORY31516.1 - 0.01 15.7 1.6 3.8 7.6 0.1 2.9 2 1 1 3 3 3 0 Sex factor F TraW protein N terminal DUF2420 PF10336.9 ORY31517.1 - 0.0051 16.8 0.3 0.0075 16.3 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) UPF0236 PF06782.11 ORY31520.1 - 0.068 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0236) UQ_con PF00179.26 ORY31521.1 - 1.5e-52 177.0 0.0 1.7e-52 176.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY31521.1 - 0.0037 17.0 0.0 0.0046 16.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 ORY31521.1 - 0.033 14.5 0.0 0.044 14.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 ORY31521.1 - 0.043 13.7 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 UEV domain 4HBT_3 PF13622.6 ORY31522.1 - 8.7e-61 206.3 0.0 1.1e-60 206.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 ORY31522.1 - 7.6e-37 126.1 0.0 1.9e-30 105.4 0.0 2.2 2 0 0 2 2 2 2 Acyl-CoA thioesterase MU2_FHA PF18221.1 ORY31523.1 - 0.0051 16.8 0.1 0.01 15.8 0.1 1.5 1 0 0 1 1 1 1 Mutator 2 Fork head associated domain CCDC92 PF14916.6 ORY31523.1 - 0.014 15.2 1.3 0.097 12.5 0.2 2.6 3 0 0 3 3 3 0 Coiled-coil domain of unknown function ZapB PF06005.12 ORY31523.1 - 0.018 15.5 2.4 0.018 15.5 2.4 3.1 1 1 1 2 2 2 0 Cell division protein ZapB SlyX PF04102.12 ORY31523.1 - 0.047 14.3 6.6 1.3 9.7 0.3 3.2 3 0 0 3 3 3 0 SlyX Golgin_A5 PF09787.9 ORY31523.1 - 0.18 11.2 7.0 0.032 13.7 1.5 1.9 1 1 1 2 2 2 0 Golgin subfamily A member 5 Med4 PF10018.9 ORY31523.1 - 0.19 11.4 0.1 0.19 11.4 0.1 2.4 2 1 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 CENP-F_N PF10481.9 ORY31523.1 - 0.41 10.2 4.1 4.8 6.7 0.0 3.0 3 0 0 3 3 3 0 Cenp-F N-terminal domain DUF5082 PF16888.5 ORY31523.1 - 0.51 10.6 4.3 3.1 8.1 0.4 3.1 2 1 2 4 4 4 0 Domain of unknown function (DUF5082) BLOC1_2 PF10046.9 ORY31523.1 - 0.52 10.6 5.0 6.8 7.1 0.0 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Csm1_N PF18504.1 ORY31523.1 - 0.94 9.9 0.1 0.94 9.9 0.1 3.2 3 1 0 3 3 3 0 Csm1 N-terminal domain RD3 PF14473.6 ORY31523.1 - 1.3 8.8 5.6 3.5 7.5 0.0 2.7 2 1 1 3 3 3 0 RD3 protein UPF0242 PF06785.11 ORY31523.1 - 1.6 8.8 5.4 1.4 9.0 0.7 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FAM76 PF16046.5 ORY31523.1 - 3.6 6.9 4.8 31 3.8 0.1 2.6 1 1 1 3 3 3 0 FAM76 protein TSC22 PF01166.18 ORY31523.1 - 5.6 7.4 11.1 4.9 7.5 1.3 3.2 3 0 0 3 3 3 0 TSC-22/dip/bun family DivIC PF04977.15 ORY31523.1 - 7 6.5 8.6 3.4 7.5 1.2 3.0 3 0 0 3 3 3 0 Septum formation initiator PLAC9 PF15205.6 ORY31523.1 - 8 6.9 6.9 24 5.4 0.1 3.4 2 1 1 4 4 4 0 Placenta-specific protein 9 Kinesin PF00225.23 ORY31524.1 - 9.2e-95 317.4 0.1 1.2e-94 316.9 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY31524.1 - 2.4e-17 63.3 0.0 8.3e-17 61.5 0.0 1.9 2 0 0 2 2 2 1 Microtubule binding AraC_N PF06719.13 ORY31524.1 - 0.036 13.7 0.2 0.51 10.0 0.0 2.2 2 0 0 2 2 2 0 AraC-type transcriptional regulator N-terminus DUF5401 PF17380.2 ORY31524.1 - 3 5.8 8.2 2.8 5.9 3.9 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5401) CHASE7 PF17151.4 ORY31525.1 - 0.066 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Periplasmic sensor domain MA3 PF02847.17 ORY31526.1 - 0.0066 16.4 0.0 0.023 14.7 0.0 1.9 1 0 0 1 1 1 1 MA3 domain Peptidase_S9_N PF02897.15 ORY31527.1 - 9.6e-118 393.6 0.4 1.3e-117 393.2 0.4 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 ORY31527.1 - 5.7e-56 189.3 0.0 1.3e-55 188.2 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family CBM65_1 PF18259.1 ORY31527.1 - 0.0094 16.1 0.4 0.03 14.5 0.0 2.0 2 0 0 2 2 2 1 Carbohydrate binding module 65 domain 1 DUF4811 PF16069.5 ORY31527.1 - 0.78 9.6 4.5 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4811) zf-H2C2_2 PF13465.6 ORY31528.1 - 9.6e-32 108.0 19.3 8e-09 35.5 0.0 5.2 5 0 0 5 5 5 5 Zinc-finger double domain zf-C2H2 PF00096.26 ORY31528.1 - 3.1e-21 74.6 25.8 2.3e-06 27.7 1.2 4.4 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY31528.1 - 1.4e-13 50.4 23.4 0.00029 21.4 1.0 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY31528.1 - 2.1e-11 43.8 10.2 0.0014 18.8 0.1 4.6 5 0 0 5 5 4 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY31528.1 - 1.3e-06 28.6 17.0 0.13 12.7 0.3 4.5 4 1 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY31528.1 - 5.5e-06 26.2 16.9 0.013 15.5 0.8 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORY31528.1 - 0.00028 20.6 16.7 0.1 12.4 1.8 4.2 4 0 0 4 4 4 2 zinc-finger C2H2-type zf-C2HE PF16278.5 ORY31528.1 - 0.0021 18.5 12.3 0.71 10.4 0.3 4.0 1 1 3 4 4 4 2 C2HE / C2H2 / C2HC zinc-binding finger BolA PF01722.18 ORY31528.1 - 0.0026 18.0 2.3 0.34 11.2 0.3 3.2 1 1 2 3 3 3 1 BolA-like protein zf-C2H2_8 PF15909.5 ORY31528.1 - 0.0034 17.7 11.0 0.011 16.0 2.3 3.1 1 1 2 3 3 3 1 C2H2-type zinc ribbon zf-Di19 PF05605.12 ORY31528.1 - 0.0048 17.2 11.9 0.027 14.8 1.8 2.3 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 ORY31528.1 - 0.014 15.2 20.9 0.077 12.8 0.5 4.9 4 1 0 4 4 4 0 C2H2-type zinc-finger domain Zn-ribbon_8 PF09723.10 ORY31528.1 - 0.031 14.4 7.2 0.82 9.8 1.1 2.9 2 2 0 2 2 2 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 ORY31528.1 - 0.037 14.4 11.9 0.48 10.8 0.3 3.7 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf_C2H2_ZHX PF18387.1 ORY31528.1 - 0.09 12.4 11.9 1.2 8.8 0.9 3.2 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain XPA_N PF01286.18 ORY31528.1 - 0.2 11.7 9.9 3.8 7.6 0.2 4.1 4 0 0 4 4 4 0 XPA protein N-terminal Elf1 PF05129.13 ORY31528.1 - 0.25 11.4 9.2 0.28 11.3 0.9 2.8 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-LYAR PF08790.11 ORY31528.1 - 0.39 10.7 6.0 3.6 7.6 0.0 3.6 4 0 0 4 4 3 0 LYAR-type C2HC zinc finger zf-UBP PF02148.19 ORY31528.1 - 0.4 11.0 8.4 18 5.8 8.4 2.4 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zinc_ribbon_15 PF17032.5 ORY31528.1 - 0.63 10.8 6.0 13 6.6 0.6 2.9 1 1 3 4 4 4 0 zinc-ribbon family DUF2072 PF09845.9 ORY31528.1 - 1.2 9.4 6.6 3.1 8.1 1.1 3.0 2 1 1 3 3 3 0 Zn-ribbon containing protein C1_4 PF07975.12 ORY31528.1 - 2.3 8.5 9.9 9.7 6.5 2.1 3.1 1 1 2 3 3 3 0 TFIIH C1-like domain zf-AN1 PF01428.16 ORY31528.1 - 2.5 8.3 12.3 2.3 8.5 0.2 4.0 4 0 0 4 4 4 0 AN1-like Zinc finger GAGA PF09237.11 ORY31528.1 - 2.5 7.9 14.8 0.84 9.5 0.9 3.4 3 1 1 4 4 4 0 GAGA factor DZR PF12773.7 ORY31528.1 - 3.8 7.6 8.8 2.3e+02 1.9 8.8 2.6 1 1 0 1 1 1 0 Double zinc ribbon TFIIS_C PF01096.18 ORY31528.1 - 4.9 7.1 9.0 2.3 8.1 0.1 3.5 4 0 0 4 4 4 0 Transcription factor S-II (TFIIS) DUF1475 PF07343.11 ORY31530.1 - 0.0018 18.1 6.8 0.0018 18.1 6.8 2.0 1 1 0 2 2 2 2 Protein of unknown function (DUF1475) DUF2834 PF11196.8 ORY31530.1 - 0.016 15.6 6.2 0.016 15.6 6.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2834) RTA1 PF04479.13 ORY31531.1 - 3.7e-55 186.7 11.0 4.7e-55 186.4 11.0 1.1 1 0 0 1 1 1 1 RTA1 like protein Sugarporin_N PF11471.8 ORY31532.1 - 0.027 14.4 2.4 0.039 13.9 0.1 2.3 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DEC-1_N PF04625.13 ORY31532.1 - 0.077 12.0 9.5 0.1 11.6 9.5 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SMN PF06003.12 ORY31532.1 - 1.7 7.9 13.8 0.35 10.1 9.3 1.8 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) YHYH PF14240.6 ORY31533.1 - 1e-10 41.9 8.4 8.6e-08 32.4 2.3 2.2 1 1 1 2 2 2 2 YHYH protein DUF2613 PF11021.8 ORY31533.1 - 0.02 15.0 2.6 0.045 13.9 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) CHU_C PF13585.6 ORY31534.1 - 0.036 14.1 0.1 0.08 13.0 0.1 1.6 1 0 0 1 1 1 0 C-terminal domain of CHU protein family zf-H2C2_2 PF13465.6 ORY31535.1 - 3.9e-37 125.0 59.8 1.5e-08 34.6 0.7 11.0 10 1 0 10 10 10 8 Zinc-finger double domain zf-C2H2 PF00096.26 ORY31535.1 - 6.2e-31 105.1 62.7 5e-06 26.7 1.4 10.1 10 0 0 10 10 10 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY31535.1 - 6e-27 92.0 63.9 0.0019 18.9 1.1 10.1 10 0 0 10 10 10 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY31535.1 - 9e-15 54.5 40.0 0.036 14.3 0.2 9.1 9 0 0 9 9 9 6 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY31535.1 - 2.4e-12 46.5 58.4 0.0015 18.5 0.6 10.0 10 0 0 10 10 10 6 C2H2-type zinc finger zf-met PF12874.7 ORY31535.1 - 6.1e-07 29.6 51.8 0.0026 18.1 0.5 9.0 9 0 0 9 9 9 4 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 ORY31535.1 - 2.1e-05 24.1 3.6 0.0023 17.7 0.3 7.5 9 0 0 9 9 8 2 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 ORY31535.1 - 2.4e-05 24.6 41.3 0.46 10.8 9.4 7.7 1 1 6 7 7 7 4 C2H2 type zinc-finger (2 copies) Yippee-Mis18 PF03226.14 ORY31535.1 - 0.0026 18.0 1.6 0.0026 18.0 1.6 4.8 3 2 2 5 5 5 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-C2H2_3rep PF18868.1 ORY31535.1 - 0.015 16.0 26.8 0.71 10.6 7.4 5.3 1 1 2 4 4 4 0 Zinc finger C2H2-type, 3 repeats GEN1_C PF18380.1 ORY31535.1 - 0.13 13.2 1.8 1.1 10.2 0.0 2.4 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain zf-C2HC_2 PF13913.6 ORY31535.1 - 0.17 11.8 0.1 0.17 11.8 0.1 5.7 7 0 0 7 7 5 0 zinc-finger of a C2HC-type GAGA PF09237.11 ORY31535.1 - 0.23 11.3 18.3 2.3 8.1 0.3 5.5 4 3 3 7 7 7 0 GAGA factor SSP160 PF06933.11 ORY31535.1 - 0.72 8.0 5.7 1.3 7.1 5.7 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf_C2H2_ZHX PF18387.1 ORY31535.1 - 0.85 9.3 32.0 0.52 10.0 2.1 6.5 5 1 1 6 6 6 0 Zinc-fingers and homeoboxes C2H2 finger domain zinc_ribbon_15 PF17032.5 ORY31535.1 - 8.1 7.3 31.3 2 9.2 0.9 5.0 1 1 3 5 5 5 0 zinc-ribbon family Actin_micro PF17003.5 ORY31535.1 - 9.6 5.3 32.0 5.8 6.0 0.5 6.4 1 1 4 5 5 5 0 Putative actin-like family RRM_1 PF00076.22 ORY31536.1 - 5.6e-26 90.2 0.0 2.4e-09 36.9 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY31536.1 - 1.5e-06 28.1 0.3 0.074 13.1 0.0 3.0 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 ORY31536.1 - 1.3e-05 24.8 0.0 0.12 12.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S9_N PF02897.15 ORY31537.1 - 7.2e-113 377.5 0.2 9.6e-113 377.1 0.2 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 ORY31537.1 - 3.9e-56 189.9 0.0 9.4e-56 188.6 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF4811 PF16069.5 ORY31537.1 - 0.38 10.6 3.9 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4811) DUF726 PF05277.12 ORY31538.1 - 2.6e-33 115.4 0.1 6.8e-33 114.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF726) OPT PF03169.15 ORY31541.1 - 1.2e-120 404.1 51.7 1.4e-120 403.9 51.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF212 PF02681.14 ORY31541.1 - 0.14 12.2 3.0 0.74 9.9 0.2 2.7 2 0 0 2 2 2 0 Divergent PAP2 family DUF2207 PF09972.9 ORY31541.1 - 4.2 6.0 6.5 13 4.4 0.8 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3523 PF12037.8 ORY31542.1 - 0.029 13.7 5.9 0.32 10.3 3.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3523) Rsc14 PF08586.10 ORY31542.1 - 0.48 11.3 2.3 1.7 9.5 1.0 2.3 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Calreticulin PF00262.18 ORY31544.1 - 8.4e-123 409.9 13.2 3.4e-100 335.5 1.9 3.2 3 1 1 4 4 4 2 Calreticulin family NDT80_PhoG PF05224.12 ORY31544.1 - 2.9e-21 76.5 9.0 1.1e-20 74.6 0.0 3.9 3 1 0 3 3 3 1 NDT80 / PhoG like DNA-binding family Glyco_transf_34 PF05637.12 ORY31545.1 - 2e-05 24.5 0.9 7.4e-05 22.6 0.9 1.8 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 ORY31545.1 - 0.002 18.1 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Ank_2 PF12796.7 ORY31546.1 - 8.7e-20 71.1 0.1 8.6e-11 42.3 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY31546.1 - 5.7e-16 58.7 0.1 0.00024 21.6 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY31546.1 - 8e-15 53.5 0.1 0.031 14.8 0.0 6.2 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 ORY31546.1 - 3.7e-10 39.8 0.0 0.005 17.2 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ion_trans PF00520.31 ORY31546.1 - 1.3e-06 27.9 17.7 1.9e-06 27.3 17.7 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_5 PF13857.6 ORY31546.1 - 2.4e-05 24.5 0.2 2.2 8.7 0.1 4.6 2 2 2 4 4 4 2 Ankyrin repeats (many copies) RNA_pol_Rpb1_5 PF04998.17 ORY31547.1 - 2.9e-89 299.0 0.0 5.6e-89 298.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 ORY31547.1 - 1e-64 217.7 0.0 1.9e-64 216.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 ORY31547.1 - 9.3e-33 113.4 0.0 1.7e-32 112.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 ORY31547.1 - 1.3e-28 100.2 1.2 1.6e-25 90.1 0.3 3.9 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 ORY31547.1 - 6.9e-16 58.1 0.1 2.8e-15 56.2 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 DUF1640 PF07798.11 ORY31547.1 - 0.26 11.3 3.6 7.3 6.6 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Pro_CA PF00484.19 ORY31548.1 - 6.6e-45 153.2 0.0 8.4e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase DUF4436 PF14494.6 ORY31550.1 - 2.9e-24 85.7 8.7 5.2e-24 84.9 8.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) DUF962 PF06127.11 ORY31550.1 - 0.065 13.3 0.0 0.61 10.2 0.0 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF962) Saf_2TM PF18303.1 ORY31550.1 - 1.1 8.8 4.2 0.37 10.4 0.4 2.1 2 1 0 2 2 2 0 SAVED-fused 2TM effector domain Peptidase_M14 PF00246.24 ORY31553.1 - 5.2e-63 213.5 0.4 7.2e-63 213.1 0.4 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase RIFIN PF02009.16 ORY31553.1 - 0.054 13.4 1.2 0.089 12.7 1.2 1.2 1 0 0 1 1 1 0 Rifin CTD_bind PF04818.13 ORY31553.1 - 0.11 13.3 0.0 0.35 11.7 0.0 1.8 1 0 0 1 1 1 0 RNA polymerase II-binding domain. dCache_1 PF02743.18 ORY31554.1 - 2.7e-11 43.7 7.3 2.3e-10 40.7 7.3 2.2 1 1 0 1 1 1 1 Cache domain DUF4191 PF13829.6 ORY31554.1 - 2.4 7.4 5.4 0.27 10.5 0.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Peptidase_M14 PF00246.24 ORY31555.1 - 2.9e-69 234.1 0.4 3.7e-69 233.7 0.4 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF2235 PF09994.9 ORY31556.1 - 1.5e-45 155.8 3.4 8.8e-45 153.3 3.4 1.9 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Globin PF00042.22 ORY31556.1 - 0.036 14.6 0.1 0.076 13.6 0.1 1.6 1 0 0 1 1 1 0 Globin DUF2235 PF09994.9 ORY31557.1 - 1.7e-57 195.0 0.0 2.5e-57 194.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2235 PF09994.9 ORY31558.1 - 3.1e-55 187.6 0.0 1.1e-54 185.7 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2235 PF09994.9 ORY31559.1 - 1.4e-54 185.4 0.0 2e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Peptidase_M14 PF00246.24 ORY31560.1 - 1.1e-28 100.9 0.0 2.5e-27 96.5 0.0 2.0 2 0 0 2 2 2 2 Zinc carboxypeptidase Thioredox_DsbH PF03190.15 ORY31561.1 - 4.7e-61 205.5 0.0 1.3e-60 204.0 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 ORY31561.1 - 1.6e-10 41.0 0.0 3.6e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Peptidase_C39 PF03412.15 ORY31561.1 - 0.092 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase C39 family Lipoxygenase PF00305.19 ORY31562.1 - 4.9e-39 134.3 4.1 6.6e-30 104.1 1.6 4.9 2 2 1 3 3 3 3 Lipoxygenase Lipoxygenase PF00305.19 ORY31563.1 - 1.4e-37 129.6 0.6 3.4e-18 65.5 0.7 4.1 2 1 2 4 4 4 4 Lipoxygenase DAGK_cat PF00781.24 ORY31564.1 - 2.5e-25 88.5 3.6 4e-25 87.9 0.2 2.0 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 ORY31564.1 - 0.019 14.2 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 ATP-NAD kinase Rossmann-like PF10727.9 ORY31564.1 - 0.079 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Rossmann-like domain ADH_N_2 PF16884.5 ORY31565.1 - 2.3e-20 72.5 0.0 4.4e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 ORY31565.1 - 2.1e-18 66.5 0.1 3.1e-18 66.0 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY31565.1 - 0.00014 22.9 0.0 0.0016 19.5 0.0 2.3 1 1 1 2 2 2 1 Zinc-binding dehydrogenase MTABC_N PF16185.5 ORY31566.1 - 0.011 15.3 1.0 0.011 15.3 1.0 2.1 2 0 0 2 2 2 0 Mitochondrial ABC-transporter N-terminal five TM region NDC10_II PF16787.5 ORY31568.1 - 0.004 16.3 0.0 0.024 13.7 0.0 2.0 2 0 0 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 HSBP1 PF06825.12 ORY31568.1 - 4.8 7.1 5.9 0.9 9.4 0.2 2.7 3 0 0 3 3 3 0 Heat shock factor binding protein 1 ATP19 PF11022.8 ORY31570.1 - 5.2e-07 29.9 0.0 6.3e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit K DUF5381 PF17353.2 ORY31570.1 - 0.23 11.2 0.2 0.47 10.2 0.1 1.5 1 1 1 2 2 2 0 Family of unknown function (DUF5381) DUF2235 PF09994.9 ORY31571.1 - 1.9e-56 191.6 0.0 3e-56 190.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Sld7_C PF18596.1 ORY31572.1 - 0.053 13.6 0.1 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 Sld7 C-terminal domain CRAL_TRIO PF00650.20 ORY31573.1 - 4.6e-21 75.2 0.0 7.9e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain Urate_ox_N PF06181.11 ORY31573.1 - 0.049 13.0 1.8 0.88 8.9 0.2 2.1 2 0 0 2 2 2 0 Urate oxidase N-terminal Peptidase_C2 PF00648.21 ORY31574.1 - 3.3e-58 197.1 0.1 1.1e-57 195.4 0.0 1.8 1 1 0 1 1 1 1 Calpain family cysteine protease MAS20 PF02064.15 ORY31574.1 - 5 7.2 13.5 15 5.7 13.5 1.8 1 0 0 1 1 1 0 MAS20 protein import receptor XRN_M PF17846.1 ORY31574.1 - 5.5 5.8 13.3 8.7 5.2 13.3 1.2 1 0 0 1 1 1 0 Xrn1 helical domain PPL5 PF18168.1 ORY31574.1 - 6.4 6.0 12.9 11 5.2 12.9 1.3 1 0 0 1 1 1 0 Prim-pol family 5 EF-hand_1 PF00036.32 ORY31575.1 - 1.5e-13 49.2 2.2 0.00066 19.0 0.1 3.8 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 ORY31575.1 - 2.1e-12 47.3 0.3 2.2e-09 37.6 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair 5_nucleotid_C PF02872.18 ORY31575.1 - 6.6e-12 45.9 0.0 1.4e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain EF-hand_6 PF13405.6 ORY31575.1 - 4.4e-10 38.7 0.7 0.038 13.9 0.1 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 ORY31575.1 - 6.6e-08 31.7 2.5 0.0004 19.7 0.1 3.9 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 ORY31575.1 - 6.4e-05 22.7 1.8 0.0047 16.7 0.3 3.0 2 1 1 3 3 3 2 EF-hand domain pair Metallophos PF00149.28 ORY31575.1 - 0.00012 22.6 0.1 0.00026 21.6 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Plant_vir_prot PF01307.17 ORY31576.1 - 0.066 13.5 0.0 5 7.4 0.0 2.1 2 0 0 2 2 2 0 Plant viral movement protein Orf78 PF06024.12 ORY31576.1 - 0.1 12.9 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 Orf78 (ac78) TPR_12 PF13424.6 ORY31577.1 - 6.9e-130 423.6 11.6 4.8e-19 68.4 0.1 8.1 1 1 7 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.6 ORY31577.1 - 8.3e-123 397.5 0.0 2e-15 56.1 0.0 8.3 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.6 ORY31577.1 - 7.9e-43 141.4 4.0 8.2e-05 22.4 0.0 8.4 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_1 PF00515.28 ORY31577.1 - 3.9e-38 127.7 22.6 1.2e-06 28.1 0.3 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 ORY31577.1 - 1.4e-29 99.8 28.9 0.00028 20.9 0.4 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 ORY31577.1 - 4.4e-22 76.4 14.1 0.00058 19.8 0.2 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 ORY31577.1 - 7.5e-20 69.8 16.6 0.086 13.3 0.1 7.9 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 ORY31577.1 - 3.1e-18 66.1 0.0 0.11 13.2 0.0 7.7 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY31577.1 - 1.3e-14 54.3 0.0 8.2e-08 32.0 0.0 2.9 1 1 1 3 3 3 3 MalT-like TPR region TPR_14 PF13428.6 ORY31577.1 - 1.8e-14 53.2 0.0 0.57 11.2 0.0 7.6 2 2 6 8 8 8 3 Tetratricopeptide repeat TPR_4 PF07721.14 ORY31577.1 - 4.7e-12 45.3 0.0 7.3 7.5 0.0 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY31577.1 - 2.3e-10 40.8 7.0 0.21 12.1 0.0 5.6 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_3 PF07720.12 ORY31577.1 - 6.9e-10 38.7 21.1 0.085 12.9 0.2 6.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_6 PF13174.6 ORY31577.1 - 1.9e-08 34.4 10.3 3 8.7 0.1 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY31577.1 - 4.4e-07 30.0 16.1 1.7 8.9 0.1 6.6 2 1 4 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 ORY31577.1 - 3.6e-06 27.2 0.4 9.8 6.6 0.0 6.4 3 1 3 7 7 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY31577.1 - 1.7e-05 24.4 23.2 2.7 7.7 0.4 7.1 7 0 0 7 7 7 3 TPR repeat TPR_9 PF13371.6 ORY31577.1 - 0.00011 22.3 0.0 3.4 7.9 0.0 5.3 5 2 2 7 7 7 1 Tetratricopeptide repeat DUF5112 PF17139.4 ORY31577.1 - 0.08 12.4 0.1 24 4.3 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF5112) 14-3-3 PF00244.20 ORY31577.1 - 0.16 11.4 0.7 56 3.1 0.1 4.1 3 1 1 5 5 5 0 14-3-3 protein PPR PF01535.20 ORY31577.1 - 8 7.0 11.5 3.7 8.0 0.1 4.5 7 0 0 7 7 6 0 PPR repeat PPP4R2 PF09184.11 ORY31579.1 - 0.00011 21.9 13.8 0.00013 21.7 13.8 1.2 1 0 0 1 1 1 1 PPP4R2 NOA36 PF06524.12 ORY31579.1 - 0.00038 19.9 20.7 0.00055 19.4 20.7 1.1 1 0 0 1 1 1 1 NOA36 protein Pes-10 PF07149.11 ORY31579.1 - 0.057 12.5 17.7 0.056 12.5 15.9 1.7 2 0 0 2 2 2 0 Pes-10 TFIIA PF03153.13 ORY31579.1 - 0.57 10.1 17.4 0.6 10.0 17.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 ORY31579.1 - 0.91 9.2 30.7 0.12 12.1 26.5 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Dppa2_A PF14049.6 ORY31579.1 - 0.91 9.7 10.2 3.4 7.9 0.0 2.7 2 1 0 2 2 2 0 Dppa2/4 conserved region in higher vertebrates SAPS PF04499.15 ORY31579.1 - 1.3 7.8 10.5 1.4 7.6 10.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DNA_pol_phi PF04931.13 ORY31579.1 - 1.7 6.6 32.6 2.9 5.9 32.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi Dicty_REP PF05086.12 ORY31579.1 - 2.1 6.2 11.7 2.8 5.8 11.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nop14 PF04147.12 ORY31579.1 - 2.4 6.3 27.6 3.4 5.8 27.6 1.2 1 0 0 1 1 1 0 Nop14-like family PI3K_1B_p101 PF10486.9 ORY31579.1 - 5.7 4.6 10.6 7.8 4.1 10.6 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit zf-C2H2 PF00096.26 ORY31580.1 - 0.053 14.0 11.0 10 6.8 2.0 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type OrsD PF12013.8 ORY31580.1 - 0.19 12.2 5.8 0.99 9.9 1.7 2.7 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 ORY31580.1 - 5 8.2 12.0 26 6.0 2.4 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 ORY31580.1 - 7.6 6.3 8.7 6 6.6 1.3 2.5 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF4201 PF13870.6 ORY31732.1 - 0.0015 18.3 4.5 0.0024 17.7 4.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) CENP-F_leu_zip PF10473.9 ORY31732.1 - 0.0072 16.4 8.0 0.2 11.7 0.1 2.1 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PEARLI-4 PF05278.12 ORY31732.1 - 0.0095 15.6 4.8 0.018 14.6 4.8 1.5 1 0 0 1 1 1 1 Arabidopsis phospholipase-like protein (PEARLI 4) Phlebovirus_NSM PF07246.11 ORY31732.1 - 0.0095 15.3 1.9 0.013 14.9 1.9 1.2 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M AAA_13 PF13166.6 ORY31732.1 - 0.01 14.5 4.8 0.013 14.2 4.8 1.1 1 0 0 1 1 1 0 AAA domain DUF4061 PF13270.6 ORY31732.1 - 0.016 15.5 1.6 0.03 14.6 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) Spc7 PF08317.11 ORY31732.1 - 0.024 13.5 4.8 0.031 13.2 4.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein COQ7 PF03232.13 ORY31732.1 - 0.026 14.3 1.9 0.048 13.4 1.9 1.4 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Atg14 PF10186.9 ORY31732.1 - 0.026 13.6 3.0 0.034 13.2 3.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 ORY31732.1 - 0.044 13.1 2.8 0.067 12.5 2.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4200 PF13863.6 ORY31732.1 - 0.067 13.6 8.9 0.11 12.9 8.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF809 PF05663.11 ORY31732.1 - 0.1 12.7 0.8 0.19 11.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF809) Shugoshin_N PF07558.11 ORY31732.1 - 0.12 12.3 1.0 1.1 9.2 0.0 2.5 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region DUF1664 PF07889.12 ORY31732.1 - 0.14 12.2 1.8 0.3 11.2 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) UPF0242 PF06785.11 ORY31732.1 - 0.16 12.1 5.0 0.3 11.2 5.1 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 ORY31732.1 - 1.4 8.7 6.2 0.81 9.5 0.2 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 ORY31732.1 - 4.1 7.9 9.8 2.8 8.4 1.5 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) SNF2_N PF00176.23 ORY31733.1 - 2.9e-20 72.3 0.0 4.1e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 ORY31733.1 - 0.0012 18.9 0.0 0.0032 17.5 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit APH PF01636.23 ORY31736.1 - 9.3e-13 48.7 0.1 2.5e-12 47.3 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 ORY31736.1 - 1.2e-11 44.2 0.0 2.1e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 ORY31736.1 - 2.3e-11 43.6 0.0 5e-10 39.2 0.0 2.2 2 1 0 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.20 ORY31736.1 - 4e-05 23.3 0.1 7.8e-05 22.4 0.1 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Peptidase_S58 PF03576.14 ORY31736.1 - 0.13 11.7 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S58 Guanylate_cyc PF00211.20 ORY31737.1 - 2.9e-49 167.2 0.0 8.2e-49 165.7 0.0 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 ORY31737.1 - 4.2e-09 36.6 0.7 2.8e-08 33.9 0.0 2.8 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 ORY31737.1 - 4.2e-05 23.5 3.8 6.4e-05 22.9 0.0 3.0 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 ORY31737.1 - 0.037 14.1 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 PAS domain TPR_2 PF07719.17 ORY31738.1 - 1e-33 112.7 34.8 0.00075 19.4 0.3 17.9 20 0 0 20 20 18 8 Tetratricopeptide repeat TPR_1 PF00515.28 ORY31738.1 - 9.2e-32 107.6 16.4 1.3e-05 24.7 0.1 14.6 17 0 0 17 17 16 6 Tetratricopeptide repeat TPR_8 PF13181.6 ORY31738.1 - 4.7e-24 82.6 9.8 0.0017 18.4 0.0 13.6 17 0 0 17 17 12 5 Tetratricopeptide repeat TPR_17 PF13431.6 ORY31738.1 - 1.4e-22 78.4 20.8 0.00018 21.7 0.1 13.2 15 0 0 15 15 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 ORY31738.1 - 3.6e-20 72.2 23.9 0.0011 19.4 0.0 12.1 12 1 1 13 13 12 5 Tetratricopeptide repeat TPR_16 PF13432.6 ORY31738.1 - 5.5e-19 68.5 32.7 0.00015 22.4 0.0 12.4 10 3 1 13 13 12 6 Tetratricopeptide repeat TPR_14 PF13428.6 ORY31738.1 - 2.8e-18 65.0 36.1 0.58 11.1 0.1 17.3 11 5 8 20 20 15 5 Tetratricopeptide repeat TPR_12 PF13424.6 ORY31738.1 - 3.5e-18 65.6 32.6 0.0049 17.1 0.1 12.6 11 2 2 13 13 12 5 Tetratricopeptide repeat TPR_11 PF13414.6 ORY31738.1 - 6.3e-16 57.8 9.3 0.015 15.0 0.0 13.8 13 2 2 15 15 15 2 TPR repeat TPR_7 PF13176.6 ORY31738.1 - 2.2e-12 46.1 15.8 0.066 13.3 0.0 10.4 11 0 0 11 11 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY31738.1 - 6.3e-10 39.2 9.6 0.18 12.1 0.1 9.4 8 2 2 10 10 10 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 ORY31738.1 - 5.3e-09 36.1 8.2 0.085 13.0 0.0 7.4 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY31738.1 - 3.2e-07 30.6 23.1 2.4 9.0 0.0 11.5 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_15 PF13429.6 ORY31738.1 - 7e-07 28.7 6.4 0.082 12.1 0.0 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 ORY31738.1 - 1.7e-05 25.1 11.2 0.25 11.7 0.1 7.4 5 2 2 7 7 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY31738.1 - 0.001 19.1 0.2 0.032 14.3 0.0 3.7 4 0 0 4 4 2 1 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.14 ORY31738.1 - 0.0021 17.5 1.2 0.17 11.2 0.0 3.9 4 0 0 4 4 4 1 Coatomer epsilon subunit RPN7 PF10602.9 ORY31738.1 - 0.0034 17.1 1.0 1 9.0 0.0 4.2 5 0 0 5 5 5 1 26S proteasome subunit RPN7 TPR_22 PF18833.1 ORY31738.1 - 0.024 14.8 0.1 0.079 13.1 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat ChAPs PF09295.10 ORY31738.1 - 0.027 13.5 0.2 1.2 8.1 0.0 3.2 4 0 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) Clathrin PF00637.20 ORY31738.1 - 0.058 13.3 0.1 1.6 8.6 0.0 3.3 3 0 0 3 3 3 0 Region in Clathrin and VPS FAT PF02259.23 ORY31738.1 - 0.077 12.2 0.5 18 4.4 0.0 4.2 4 1 1 5 5 5 0 FAT domain Rota_NSP4 PF01452.16 ORY31738.1 - 0.51 10.0 2.3 11 5.7 1.3 2.5 2 0 0 2 2 2 0 Rotavirus non structural protein BTAD PF03704.17 ORY31738.1 - 0.68 10.4 9.3 45 4.5 0.2 5.8 6 1 0 6 6 6 0 Bacterial transcriptional activator domain cNMP_binding PF00027.29 ORY31739.1 - 2e-16 59.8 0.0 3.8e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain aGPT-Pplase1 PF18723.1 ORY31740.1 - 1.1e-09 38.1 0.5 5.1e-09 36.0 0.5 2.0 1 1 0 1 1 1 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 bZIP_1 PF00170.21 ORY31740.1 - 9.3e-09 35.3 15.2 2.4e-07 30.7 6.8 2.8 1 1 1 2 2 2 2 bZIP transcription factor TSC22 PF01166.18 ORY31740.1 - 0.17 12.2 3.7 2.2 8.7 0.9 3.1 2 1 1 3 3 3 0 TSC-22/dip/bun family bZIP_Maf PF03131.17 ORY31740.1 - 0.77 10.3 18.8 0.076 13.5 12.3 2.7 1 1 2 3 3 3 0 bZIP Maf transcription factor bZIP_2 PF07716.15 ORY31740.1 - 1.1 9.4 25.6 0.14 12.2 6.2 3.3 2 1 1 3 3 3 0 Basic region leucine zipper bZIP_1 PF00170.21 ORY31742.1 - 0.00063 19.8 11.3 0.0011 19.0 7.5 2.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORY31742.1 - 0.064 13.3 16.8 0.072 13.2 8.2 2.4 2 0 0 2 2 2 0 Basic region leucine zipper PAP_assoc PF03828.19 ORY31743.1 - 2.6e-11 43.6 0.1 1.1e-10 41.5 0.0 2.1 2 0 0 2 2 2 1 Cid1 family poly A polymerase zf-C2H2 PF00096.26 ORY31744.1 - 0.0038 17.6 0.8 0.0038 17.6 0.8 2.7 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY31744.1 - 0.072 14.0 3.4 0.1 13.5 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 ORY31744.1 - 0.47 10.9 1.6 0.7 10.4 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type LRR_8 PF13855.6 ORY31745.1 - 1.1e-12 47.5 6.7 0.00081 19.1 0.2 4.1 1 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY31745.1 - 1.7e-08 34.6 12.3 0.00018 21.8 2.3 3.5 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY31745.1 - 8.1e-06 25.7 6.4 3.6 8.5 0.0 5.5 6 0 0 6 6 6 2 Leucine Rich Repeat F-box-like PF12937.7 ORY31745.1 - 0.17 11.8 0.1 0.47 10.4 0.1 1.8 1 0 0 1 1 1 0 F-box-like LRR_6 PF13516.6 ORY31745.1 - 1.4 9.2 0.0 1.4 9.2 0.0 3.5 4 0 0 4 4 4 0 Leucine Rich repeat SMC_N PF02463.19 ORY31746.1 - 1.8e-27 96.3 0.0 3e-27 95.5 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORY31746.1 - 4.3e-10 40.4 23.0 4.3e-10 40.4 23.0 5.5 3 2 0 3 3 3 1 AAA domain AAA_15 PF13175.6 ORY31746.1 - 5.7e-07 29.6 0.5 5.7e-07 29.6 0.5 3.7 3 2 0 3 3 3 1 AAA ATPase domain SMC_hinge PF06470.13 ORY31746.1 - 0.00087 19.6 0.6 0.019 15.3 0.0 3.1 2 1 0 2 2 2 1 SMC proteins Flexible Hinge Domain SlyX PF04102.12 ORY31746.1 - 0.0026 18.3 1.3 0.0026 18.3 1.3 7.8 4 3 3 7 7 7 1 SlyX AAA_29 PF13555.6 ORY31746.1 - 0.0028 17.3 0.0 0.0061 16.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain UvrA_DNA-bind PF17755.1 ORY31746.1 - 0.01 16.1 0.6 0.95 9.8 0.0 2.9 2 0 0 2 2 2 0 UvrA DNA-binding domain AAA_21 PF13304.6 ORY31746.1 - 0.015 15.1 2.5 0.34 10.7 0.9 2.8 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system RPEL PF02755.15 ORY31747.1 - 0.78 9.5 3.2 2.9 7.7 0.0 2.8 3 0 0 3 3 3 0 RPEL repeat Ofd1_CTDD PF10637.9 ORY31748.1 - 1.1e-47 162.6 0.0 5.3e-43 147.2 0.1 3.2 2 2 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 ORY31748.1 - 2e-29 102.1 0.0 8e-28 97.0 0.0 2.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 ORY31748.1 - 9.2e-14 52.1 0.0 3e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Nodulin-like PF06813.13 ORY31750.1 - 1.1e-14 54.6 14.2 2.5e-14 53.4 14.2 1.6 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 ORY31750.1 - 1.2e-11 44.1 20.4 8.1e-08 31.6 16.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 ORY31751.1 - 3.1e-79 266.1 0.0 4e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY31751.1 - 2.5e-42 145.0 0.0 3.5e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY31751.1 - 5e-08 32.6 0.0 1e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like KA1 PF02149.19 ORY31751.1 - 3.2e-06 26.8 0.1 7e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 APH PF01636.23 ORY31751.1 - 7.1e-05 22.8 0.1 0.00041 20.3 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORY31751.1 - 0.00011 21.8 1.0 0.00019 21.1 0.4 1.6 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 ORY31751.1 - 0.00096 18.6 0.1 0.002 17.6 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY31751.1 - 0.023 13.6 0.3 0.035 13.1 0.3 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 ORY31751.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase GATA PF00320.27 ORY31752.1 - 5.6e-12 45.0 3.2 9e-12 44.4 3.2 1.3 1 0 0 1 1 1 1 GATA zinc finger TPR_12 PF13424.6 ORY31753.1 - 3.8e-34 116.8 12.2 3.9e-13 49.5 0.5 2.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 ORY31753.1 - 7e-32 108.4 0.0 1.3e-06 28.1 0.0 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY31753.1 - 9.5e-21 72.2 6.4 0.00048 20.0 0.1 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 ORY31753.1 - 3.7e-18 64.1 4.9 0.0039 17.1 0.1 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 ORY31753.1 - 4.2e-16 58.0 5.0 0.0034 17.1 0.1 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 ORY31753.1 - 1.1e-13 50.5 0.1 0.14 12.6 0.0 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORY31753.1 - 3.7e-13 48.6 7.7 0.021 15.0 0.1 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 ORY31753.1 - 6.5e-11 42.7 1.1 0.015 15.9 0.2 4.0 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_4 PF07721.14 ORY31753.1 - 3e-10 39.7 0.0 0.6 10.9 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORY31753.1 - 8.1e-07 29.4 2.3 4.3 8.4 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat Herpes_capsid PF06112.11 ORY31753.1 - 1.3e-06 28.6 0.1 3.7 7.6 0.0 4.0 1 1 3 4 4 4 2 Gammaherpesvirus capsid protein YjzC PF14168.6 ORY31753.1 - 2.6e-06 27.7 0.1 7.7 7.0 0.0 4.2 4 0 0 4 4 4 1 YjzC-like protein TPR_MalT PF17874.1 ORY31753.1 - 0.00013 21.5 1.2 0.00031 20.2 1.2 1.6 1 1 0 1 1 1 1 MalT-like TPR region TPR_19 PF14559.6 ORY31753.1 - 0.00014 22.3 1.5 1.1 9.8 0.1 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat HypF_C PF17788.1 ORY31753.1 - 0.0024 18.6 0.3 17 6.2 0.0 3.6 1 1 2 3 3 3 0 HypF Kae1-like domain TPR_6 PF13174.6 ORY31753.1 - 0.0067 17.0 8.0 22 5.9 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat UVR PF02151.19 ORY31753.1 - 0.042 13.6 0.0 1.2e+02 2.7 0.0 3.9 4 0 0 4 4 4 0 UvrB/uvrC motif SPO22 PF08631.10 ORY31753.1 - 0.061 12.8 0.3 6 6.3 0.1 2.3 1 1 1 2 2 2 0 Meiosis protein SPO22/ZIP4 like RPN7 PF10602.9 ORY31753.1 - 0.12 12.0 0.5 49 3.6 0.0 3.5 1 1 3 4 4 4 0 26S proteasome subunit RPN7 KxDL PF10241.9 ORY31754.1 - 0.22 11.9 0.1 0.22 11.9 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein Histone PF00125.24 ORY31908.1 - 1.2e-14 54.8 0.3 1.3e-14 54.7 0.3 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORY31908.1 - 0.00056 20.0 0.1 0.00058 20.0 0.1 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 ORY31908.1 - 0.012 15.9 0.1 0.014 15.6 0.1 1.1 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 ORY31908.1 - 0.019 15.4 0.1 0.019 15.4 0.1 1.1 1 0 0 1 1 1 0 CENP-S protein PIF1 PF05970.14 ORY31909.1 - 1.4e-13 50.7 0.0 1.1e-12 47.8 0.0 2.0 2 0 0 2 2 2 1 PIF1-like helicase Helitron_like_N PF14214.6 ORY31909.1 - 3.2e-11 43.8 0.0 7.2e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 ORY31909.1 - 4.8e-08 33.0 0.0 9.8e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY31909.1 - 0.00022 21.6 0.0 0.00048 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain zf_C2H2_6 PF18450.1 ORY31909.1 - 0.059 13.1 0.4 0.34 10.7 0.4 2.5 1 0 0 1 1 1 0 Zinc Finger domain AAA_16 PF13191.6 ORY31909.1 - 0.12 12.8 0.1 0.45 10.9 0.1 2.0 1 0 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 ORY31909.1 - 0.16 12.2 0.0 20 5.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase T3SSipB PF16535.5 ORY31910.1 - 4.1 7.9 16.0 15 6.0 16.0 2.0 1 1 0 1 1 1 0 Type III cell invasion protein SipB GH3 PF03321.13 ORY31912.1 - 4.9e-56 190.7 0.0 6.1e-56 190.4 0.0 1.0 1 0 0 1 1 1 1 GH3 auxin-responsive promoter Phage_Coat_A PF05357.13 ORY31912.1 - 0.11 12.3 0.0 0.77 9.6 0.0 2.3 2 0 0 2 2 2 0 Phage Coat Protein A C1_1 PF00130.22 ORY32063.1 - 0.068 13.1 7.6 0.13 12.2 7.6 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 ORY32063.1 - 0.46 10.4 7.6 1 9.3 7.6 1.6 1 0 0 1 1 1 0 PHD-finger DZR PF12773.7 ORY32063.1 - 3.8 7.6 9.8 15 5.7 9.9 1.9 1 1 1 2 2 2 0 Double zinc ribbon SIKE PF05769.11 ORY32065.1 - 1.4 8.8 9.3 0.077 12.9 1.6 2.6 3 0 0 3 3 3 0 SIKE family LRR_8 PF13855.6 ORY32213.1 - 4.3e-09 36.0 10.0 0.004 16.9 0.5 3.6 1 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 ORY32213.1 - 2.3e-08 34.2 9.1 0.051 14.0 0.5 4.5 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORY32213.1 - 0.00019 21.3 0.0 0.00048 20.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 ORY32213.1 - 0.0016 18.7 6.5 20 6.2 0.2 5.7 5 1 0 5 5 5 1 Leucine Rich Repeat F-box PF00646.33 ORY32213.1 - 0.006 16.4 0.0 0.019 14.8 0.0 1.9 2 0 0 2 2 2 1 F-box domain Pribosyltran PF00156.27 ORY32382.1 - 2.4e-08 33.6 0.0 4.3e-08 32.8 0.0 1.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain OpuAC PF04069.12 ORY32389.1 - 4.2e-12 46.2 0.1 2e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 Substrate binding domain of ABC-type glycine betaine transport system ATP-synt_A PF00119.20 ORY32389.1 - 0.15 12.0 0.2 0.28 11.1 0.2 1.3 1 0 0 1 1 1 0 ATP synthase A chain Nucleo_LEF-12 PF06256.11 ORY32391.1 - 0.44 10.3 2.3 0.83 9.4 0.2 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus LEF-12 protein Macin PF14865.6 ORY32391.1 - 4.8 7.8 9.0 0.49 11.0 1.6 2.8 2 1 1 3 3 3 0 Macin CFEM PF05730.11 ORY32392.1 - 0.042 13.9 1.6 0.079 13.1 1.6 1.5 1 0 0 1 1 1 0 CFEM domain Baculo_E56 PF04639.12 ORY32392.1 - 0.046 13.0 0.0 0.058 12.7 0.0 1.1 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope OpuAC PF04069.12 ORY32393.1 - 3.8e-15 56.2 0.0 9.2e-07 28.7 0.0 2.4 2 0 0 2 2 2 2 Substrate binding domain of ABC-type glycine betaine transport system Baculo_E56 PF04639.12 ORY32395.1 - 0.0061 15.9 0.1 0.0081 15.5 0.1 1.1 1 0 0 1 1 1 1 Baculoviral E56 protein, specific to ODV envelope CFEM PF05730.11 ORY32395.1 - 0.029 14.4 1.9 0.055 13.6 1.9 1.5 1 0 0 1 1 1 0 CFEM domain Nop14 PF04147.12 ORY32396.1 - 1.9e-230 767.6 55.6 9.5e-230 765.3 55.6 1.8 1 1 0 1 1 1 1 Nop14-like family tRNA-synt_2 PF00152.20 ORY32396.1 - 0.0037 16.4 0.0 0.0083 15.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Noc2 PF03715.13 ORY32396.1 - 0.73 9.0 13.2 0.053 12.8 3.3 3.4 3 1 0 3 3 3 0 Noc2p family Ferrochelatase PF00762.19 ORY32397.1 - 7.8e-104 347.2 0.0 8.8e-104 347.0 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase LRR_4 PF12799.7 ORY32398.1 - 3.5e-20 71.7 53.2 3.8e-05 24.0 0.9 10.2 5 3 7 12 12 12 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORY32398.1 - 0.013 15.0 23.0 4.4 6.8 0.4 6.4 1 1 5 6 6 6 0 Leucine-rich repeat SPRY PF00622.28 ORY32399.1 - 4.3e-29 101.1 1.7 2e-22 79.6 0.2 2.5 2 0 0 2 2 2 2 SPRY domain Neuralized PF07177.12 ORY32399.1 - 0.015 15.3 0.0 0.17 11.8 0.0 2.3 2 0 0 2 2 2 0 Neuralized Proteasom_PSMB PF10508.9 ORY32399.1 - 0.025 13.1 0.1 0.63 8.5 0.0 2.5 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit RICTOR_M PF14666.6 ORY32399.1 - 0.062 13.1 1.6 8.4 6.2 0.0 3.3 3 1 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain V-ATPase_H_C PF11698.8 ORY32399.1 - 0.12 12.4 4.9 8.4 6.5 0.1 5.3 3 2 4 7 7 7 0 V-ATPase subunit H IFT43 PF15305.6 ORY32400.1 - 5.6e-30 104.3 2.5 5.6e-30 104.3 2.5 2.7 2 1 1 3 3 3 1 Intraflagellar transport protein 43 CDC27 PF09507.10 ORY32400.1 - 0.14 11.5 21.3 0.18 11.1 21.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.12 ORY32400.1 - 1.5 6.9 21.0 1.8 6.7 21.0 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 ORY32400.1 - 3.2 7.2 18.3 5.1 6.6 18.3 1.3 1 0 0 1 1 1 0 PPP4R2 RRN3 PF05327.11 ORY32400.1 - 4.9 5.6 9.4 5.9 5.3 9.4 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Astro_capsid_p PF12226.8 ORY32400.1 - 5.3 6.1 13.5 8.9 5.4 13.5 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein PBP1_TM PF14812.6 ORY32400.1 - 6.4 7.2 40.9 0.51 10.7 2.0 2.5 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Arm PF00514.23 ORY32401.1 - 1.9e-09 37.2 0.0 0.24 11.5 0.0 5.5 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 ORY32401.1 - 0.00074 20.0 0.6 0.092 13.3 0.1 3.2 3 0 0 3 3 3 1 HEAT-like repeat RTP1_C1 PF10363.9 ORY32401.1 - 0.0076 16.4 0.5 0.053 13.7 0.0 2.6 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_2 PF13646.6 ORY32401.1 - 0.019 15.4 0.0 0.073 13.5 0.0 2.1 1 1 0 1 1 1 0 HEAT repeats RasGEF_N_2 PF14663.6 ORY32401.1 - 0.15 12.5 1.6 0.25 11.7 0.1 2.2 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain bZIP_2 PF07716.15 ORY32402.1 - 8.8e-05 22.5 3.1 8.8e-05 22.5 3.1 3.6 4 0 0 4 4 4 1 Basic region leucine zipper bZIP_1 PF00170.21 ORY32402.1 - 0.01 15.9 3.3 0.01 15.9 3.3 3.0 3 0 0 3 3 3 0 bZIP transcription factor Bacillus_HBL PF05791.11 ORY32402.1 - 0.059 13.2 1.6 3.6 7.4 0.3 2.7 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) F_actin_bind PF08919.10 ORY32402.1 - 0.13 12.4 3.2 0.47 10.6 0.2 2.7 2 0 0 2 2 2 0 F-actin binding PGBA_C PF15437.6 ORY32402.1 - 0.18 12.2 4.0 0.15 12.5 2.1 1.8 2 0 0 2 2 2 0 Plasminogen-binding protein pgbA C-terminal zf_CCCH_4 PF18345.1 ORY32403.1 - 2.6e-05 24.1 1.1 4.6e-05 23.3 1.1 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 ORY32403.1 - 0.0011 18.8 0.9 0.0023 17.8 0.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 ORY32403.1 - 0.0025 17.6 0.9 0.0059 16.4 0.9 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 ORY32403.1 - 0.048 14.2 5.4 0.048 14.2 5.4 2.0 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger GFRP PF06399.13 ORY32403.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) WD40 PF00400.32 ORY32404.1 - 3.3e-10 40.4 11.8 0.00064 20.5 0.1 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY32404.1 - 0.0013 19.0 0.0 0.056 13.7 0.0 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Dynein_IC2 PF11540.8 ORY32404.1 - 0.028 14.4 0.3 0.056 13.4 0.3 1.5 1 0 0 1 1 1 0 Cytoplasmic dynein 1 intermediate chain 2 Frtz PF11768.8 ORY32404.1 - 0.076 11.3 0.0 2 6.6 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Ion_trans_2 PF07885.16 ORY32406.1 - 5.9e-26 90.2 27.6 3.7e-14 52.4 10.9 3.2 3 0 0 3 3 3 2 Ion channel DUF348 PF03990.14 ORY32407.1 - 0.087 12.6 1.0 11 5.9 0.6 2.3 2 0 0 2 2 2 0 G5-linked-Ubiquitin-like domain ASF1_hist_chap PF04729.13 ORY32408.1 - 2.6e-61 206.1 0.1 2.8e-61 206.0 0.1 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone Ribosomal_L26 PF16906.5 ORY32409.1 - 1.8e-34 118.0 4.6 2.1e-34 117.8 4.6 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 ORY32409.1 - 3.4e-08 33.2 5.3 4.5e-08 32.8 4.2 1.7 2 0 0 2 2 2 1 KOW motif Methyltrans_RNA PF04452.14 ORY32409.1 - 0.051 12.9 0.5 0.061 12.6 0.5 1.1 1 0 0 1 1 1 0 RNA methyltransferase LSM PF01423.22 ORY32410.1 - 2.3e-16 59.2 0.3 2.9e-16 58.9 0.3 1.1 1 0 0 1 1 1 1 LSM domain zf-CCCH PF00642.24 ORY32411.1 - 5.5e-05 23.0 27.1 0.16 11.9 1.0 5.3 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY32411.1 - 0.0011 18.9 2.6 0.0011 18.9 2.6 5.7 5 1 0 5 5 5 3 Zinc finger domain Torus PF16131.5 ORY32411.1 - 0.034 14.9 0.5 0.034 14.9 0.5 4.9 2 1 3 5 5 5 0 Torus domain zf-CCCH_3 PF15663.5 ORY32411.1 - 0.48 10.7 23.5 0.13 12.5 4.1 4.0 2 1 2 4 4 4 0 Zinc-finger containing family ANF_receptor PF01094.28 ORY32413.1 - 0.00025 20.3 0.0 0.00028 20.1 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 ORY32414.1 - 2.6e-17 63.4 27.2 2.9e-17 63.2 27.2 1.0 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR CcmH PF03918.14 ORY32414.1 - 0.17 11.1 0.1 0.39 10.0 0.1 1.6 1 0 0 1 1 1 0 Cytochrome C biogenesis protein DUF4515 PF14988.6 ORY32415.1 - 2.2e-08 34.2 30.4 4.3e-08 33.3 30.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) DUF4618 PF15397.6 ORY32415.1 - 0.0003 20.3 29.8 0.00045 19.7 29.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) MSV199 PF10553.9 ORY32415.1 - 5.3 7.3 12.6 0.082 13.2 1.8 2.4 2 0 0 2 2 2 0 MSV199 domain Phage_GP20 PF06810.11 ORY32416.1 - 0.035 13.9 2.8 0.048 13.5 2.8 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF4407 PF14362.6 ORY32416.1 - 0.056 12.8 0.4 0.063 12.6 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-MYND PF01753.18 ORY32417.1 - 9.5e-11 41.6 12.5 1.9e-10 40.7 12.5 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY32417.1 - 0.36 11.2 8.2 2.7 8.3 8.2 2.2 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-MIZ PF02891.20 ORY32418.1 - 7e-19 67.3 2.3 1.8e-18 66.0 2.3 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 ORY32418.1 - 3.3e-08 33.2 1.9 7.9e-08 32.0 1.9 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit FKBP26_C PF18046.1 ORY32418.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.5 1 0 0 1 1 1 0 FKBP26_C-terminal Ribosomal_S22 PF08136.11 ORY32418.1 - 0.15 12.4 0.0 0.33 11.3 0.0 1.6 1 0 0 1 1 1 0 30S ribosomal protein subunit S22 family VATC PF18716.1 ORY32418.1 - 3.6 7.5 16.1 2 8.3 11.4 2.6 2 1 0 2 2 2 0 Vms1-associating treble clef domain Ribosomal_60s PF00428.19 ORY32419.1 - 1.6e-27 95.9 17.5 2.2e-27 95.5 17.5 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2275 PF10039.9 ORY32419.1 - 0.013 15.6 1.9 0.018 15.2 1.9 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) Cytomega_UL84 PF06284.11 ORY32419.1 - 0.17 10.3 0.7 0.19 10.2 0.7 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF2057 PF09829.9 ORY32419.1 - 0.42 10.7 1.7 0.48 10.6 1.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF3138 PF11336.8 ORY32419.1 - 2.4 6.6 7.4 2.5 6.6 7.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) eIF-1a PF01176.19 ORY32420.1 - 8.5e-21 73.5 0.0 1.3e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 INTS2 PF14750.6 ORY32421.1 - 3.7e-97 326.1 24.3 1.4e-96 324.3 24.2 1.9 1 1 0 1 1 1 1 Integrator complex subunit 2 ANF_receptor PF01094.28 ORY32423.1 - 1.4e-18 67.1 0.0 1.8e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY32423.1 - 1.9e-05 24.5 0.1 3.2e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Periplasmic binding protein 7tm_3 PF00003.22 ORY32424.1 - 7.4e-10 39.0 12.3 1.1e-09 38.5 12.3 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR AAA PF00004.29 ORY32425.1 - 3e-95 315.6 0.0 9.6e-47 158.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY32425.1 - 2.2e-25 88.2 0.1 4.1e-11 42.5 0.0 3.0 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 ORY32425.1 - 2.5e-14 53.3 0.0 5.9e-07 29.4 0.0 3.2 4 0 0 4 4 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY32425.1 - 2.4e-12 47.5 2.6 0.0003 21.2 0.0 5.0 3 2 0 4 4 3 2 AAA ATPase domain AAA_2 PF07724.14 ORY32425.1 - 1.5e-11 44.7 0.0 2.2e-05 24.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 ORY32425.1 - 1.9e-11 44.1 0.1 0.00038 20.5 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY32425.1 - 1e-10 42.0 0.5 0.012 15.9 0.0 4.5 3 2 0 3 3 2 2 AAA domain AAA_18 PF13238.6 ORY32425.1 - 1.4e-08 35.3 2.1 0.062 13.9 0.0 4.1 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.6 ORY32425.1 - 2.6e-08 34.1 0.0 0.0061 16.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 ORY32425.1 - 3.6e-08 33.0 0.3 0.0071 15.7 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 ORY32425.1 - 4e-08 33.4 0.0 0.0039 17.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 ORY32425.1 - 7.2e-08 32.8 0.0 0.018 15.4 0.0 2.9 2 2 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 ORY32425.1 - 1e-07 31.9 0.0 0.0045 16.8 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein ABC_tran PF00005.27 ORY32425.1 - 2.2e-07 31.4 0.6 0.0034 17.9 0.0 3.2 3 0 0 3 3 2 2 ABC transporter NACHT PF05729.12 ORY32425.1 - 2.3e-07 30.9 0.1 0.071 13.0 0.0 3.6 3 1 1 4 4 3 2 NACHT domain TIP49 PF06068.13 ORY32425.1 - 1.1e-06 28.1 0.2 0.005 16.1 0.1 2.6 2 1 1 3 3 3 2 TIP49 P-loop domain AAA_25 PF13481.6 ORY32425.1 - 1.3e-06 28.1 0.3 0.4 10.2 0.1 4.0 3 1 1 4 4 4 2 AAA domain AAA_28 PF13521.6 ORY32425.1 - 1.6e-05 25.2 0.0 0.24 11.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 ORY32425.1 - 1.6e-05 24.6 0.0 0.62 9.8 0.0 3.6 3 1 0 3 3 3 2 Sigma-54 interaction domain AAA_7 PF12775.7 ORY32425.1 - 2.3e-05 24.0 0.0 0.12 11.8 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 ORY32425.1 - 2.4e-05 23.7 0.1 0.23 10.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin ATPase PF06745.13 ORY32425.1 - 2.6e-05 23.7 0.3 0.52 9.6 0.0 3.5 2 1 0 3 3 3 1 KaiC Rad17 PF03215.15 ORY32425.1 - 3.6e-05 23.8 0.0 0.37 10.7 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain Viral_helicase1 PF01443.18 ORY32425.1 - 8.7e-05 22.4 0.0 0.27 10.9 0.0 2.5 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 ORY32425.1 - 0.00025 20.3 0.1 0.59 9.3 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_24 PF13479.6 ORY32425.1 - 0.0003 20.6 0.0 0.24 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 ORY32425.1 - 0.00032 20.7 0.0 0.4 10.6 0.0 3.5 3 1 0 3 3 2 1 ATPase domain predominantly from Archaea TsaE PF02367.17 ORY32425.1 - 0.00046 20.2 0.0 0.45 10.5 0.0 2.4 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 ORY32425.1 - 0.00047 20.3 0.0 1.6 8.8 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain TniB PF05621.11 ORY32425.1 - 0.00048 19.6 0.0 3.8 6.9 0.0 3.4 2 1 1 3 3 3 0 Bacterial TniB protein AAA_3 PF07726.11 ORY32425.1 - 0.00049 20.0 0.0 0.59 10.0 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) YL1 PF05764.13 ORY32425.1 - 0.00063 19.9 21.0 0.0014 18.9 21.0 1.5 1 0 0 1 1 1 1 YL1 nuclear protein Parvo_NS1 PF01057.17 ORY32425.1 - 0.0012 18.0 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.13 ORY32425.1 - 0.0023 17.1 0.0 1.8 7.6 0.0 2.8 3 0 0 3 3 2 1 Protein of unknown function (DUF815) CPT PF07931.12 ORY32425.1 - 0.006 16.4 0.0 0.097 12.5 0.0 2.3 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Cytidylate_kin2 PF13189.6 ORY32425.1 - 0.011 15.9 0.3 0.34 11.0 0.0 2.9 3 0 0 3 3 2 0 Cytidylate kinase-like family Vps4_C PF09336.10 ORY32425.1 - 0.017 15.1 0.8 8 6.5 0.0 3.8 4 0 0 4 4 3 0 Vps4 C terminal oligomerisation domain SKI PF01202.22 ORY32425.1 - 0.02 15.0 0.0 8.8 6.4 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase ATP-synt_ab PF00006.25 ORY32425.1 - 0.029 14.0 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AFG1_ATPase PF03969.16 ORY32425.1 - 0.032 13.1 0.0 2.9 6.7 0.0 2.8 3 0 0 3 3 3 0 AFG1-like ATPase PhoH PF02562.16 ORY32425.1 - 0.035 13.6 0.0 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein RsgA_GTPase PF03193.16 ORY32425.1 - 0.056 13.3 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 ORY32425.1 - 0.066 13.0 0.0 5.3 6.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain FeoB_N PF02421.18 ORY32425.1 - 0.077 12.5 0.1 2.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B MMR_HSR1 PF01926.23 ORY32425.1 - 0.093 12.8 0.0 1.5 9.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 ORY32425.1 - 0.14 11.9 0.0 12 5.7 0.0 2.7 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation DNA_pol_phi PF04931.13 ORY32425.1 - 0.16 10.1 29.1 0.26 9.4 29.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF591 PF04569.14 ORY32425.1 - 0.18 11.9 1.1 0.56 10.3 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function Adeno_IVa2 PF02456.15 ORY32425.1 - 0.23 10.2 0.5 14 4.3 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_17 PF13207.6 ORY32425.1 - 0.46 10.9 11.4 2.5 8.5 0.0 3.8 4 0 0 4 4 2 0 AAA domain DUF2457 PF10446.9 ORY32425.1 - 0.7 9.0 24.0 1.3 8.1 24.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) AAA_11 PF13086.6 ORY32425.1 - 7.6 6.2 18.4 7.9 6.2 0.0 3.9 3 1 0 3 3 2 0 AAA domain VWA_2 PF13519.6 ORY32426.1 - 0.01 16.5 2.1 0.089 13.4 0.1 3.4 3 1 0 3 3 3 0 von Willebrand factor type A domain DUF2201 PF09967.9 ORY32426.1 - 0.028 14.5 0.2 2.2 8.5 0.0 3.0 3 0 0 3 3 3 0 VWA-like domain (DUF2201) NPL4 PF05021.15 ORY32427.1 - 2.8e-111 371.8 0.0 3.6e-111 371.4 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 ORY32427.1 - 2e-61 206.4 0.1 3.1e-61 205.8 0.1 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 ORY32427.1 - 1.1e-08 35.4 0.0 2.4e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Polyketide_cyc2 PF10604.9 ORY32427.1 - 0.00011 22.5 0.5 0.00011 22.5 0.5 2.1 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 ORY32427.1 - 0.069 13.4 0.1 0.32 11.2 0.1 2.0 2 0 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport Methyltransf_16 PF10294.9 ORY32428.1 - 2e-13 50.5 0.0 3.2e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase RRM_1 PF00076.22 ORY32428.1 - 2.8e-11 43.1 0.0 4.2e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY32428.1 - 0.03 14.3 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif CAP PF00188.26 ORY32429.1 - 2.8e-13 50.8 0.7 4.3e-13 50.2 0.7 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Acid_PPase PF12689.7 ORY32430.1 - 1.3e-45 155.3 0.0 1.4e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase NIF PF03031.18 ORY32430.1 - 0.00027 20.7 0.0 0.00033 20.4 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase PF00702.26 ORY32430.1 - 0.1 12.9 0.0 0.72 10.1 0.0 1.9 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Sulfate_transp PF00916.20 ORY32431.1 - 2.3e-69 234.0 23.7 3.3e-69 233.5 23.7 1.2 1 0 0 1 1 1 1 Sulfate permease family Sulfate_transp PF00916.20 ORY32432.1 - 1.6e-69 234.5 24.2 2.5e-69 233.9 24.2 1.2 1 0 0 1 1 1 1 Sulfate permease family DAD PF02109.16 ORY32432.1 - 0.0028 18.0 1.3 0.012 15.9 1.3 2.1 1 0 0 1 1 1 1 DAD family RIO1 PF01163.22 ORY32433.1 - 7.7e-49 165.8 0.0 1.1e-48 165.3 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 ORY32433.1 - 1.6e-34 117.9 0.1 3.8e-34 116.8 0.1 1.6 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 ORY32433.1 - 1.2e-08 35.2 0.0 0.00046 20.2 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 ORY32433.1 - 8.3e-06 25.3 0.1 0.083 12.2 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.7 ORY32435.1 - 2.9e-32 111.1 4.3 8.2e-15 55.2 0.1 4.1 3 1 0 4 4 4 2 Ankyrin repeats (3 copies) DHHC PF01529.20 ORY32435.1 - 6.6e-31 107.2 22.2 6.6e-31 107.2 22.2 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.6 ORY32435.1 - 1.4e-27 95.3 3.6 1.3e-08 35.0 0.1 4.0 3 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY32435.1 - 5.8e-25 84.6 3.1 1.3e-06 28.3 0.1 7.4 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 ORY32435.1 - 9.8e-24 83.4 4.9 1.8e-09 38.0 0.1 4.7 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY32435.1 - 8e-21 73.5 5.6 5.7e-05 23.4 0.1 7.2 7 0 0 7 7 7 5 Ankyrin repeat ERGIC_N PF13850.6 ORY32435.1 - 1.4 9.4 3.6 1.9 8.9 0.2 2.5 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Herpes_gE PF02480.16 ORY32436.1 - 0.084 11.6 0.2 0.11 11.2 0.2 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Plasmod_Pvs28 PF06247.11 ORY32437.1 - 1.6 9.1 7.9 5.9 7.3 0.3 3.5 3 0 0 3 3 3 0 Pvs28 EGF domain Pet191_N PF10203.9 ORY32437.1 - 3.3 8.1 6.1 18 5.7 0.4 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 CorA PF01544.18 ORY32438.1 - 6e-55 186.6 0.9 6e-55 186.6 0.9 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein PARP PF00644.20 ORY32440.1 - 4e-67 225.6 0.0 4e-67 225.6 0.0 2.1 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 ORY32440.1 - 4.8e-42 143.3 0.2 8.6e-42 142.5 0.2 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 ORY32440.1 - 1.9e-27 95.1 0.4 5.7e-27 93.6 0.4 1.9 1 0 0 1 1 1 1 WGR domain NOA36 PF06524.12 ORY32440.1 - 0.014 14.8 6.6 0.022 14.1 6.6 1.3 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.18 ORY32440.1 - 0.041 13.8 8.2 0.07 13.0 8.2 1.3 1 0 0 1 1 1 0 Myc amino-terminal region PTPRCAP PF15713.5 ORY32440.1 - 0.36 11.1 9.5 1.1 9.6 9.5 1.8 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated PPP4R2 PF09184.11 ORY32440.1 - 0.49 9.9 16.6 0.92 9.0 16.6 1.4 1 0 0 1 1 1 0 PPP4R2 DUF4746 PF15928.5 ORY32440.1 - 1.2 8.5 12.7 2.1 7.7 12.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Pox_Ag35 PF03286.14 ORY32440.1 - 2.1 8.1 14.4 4.3 7.1 14.4 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SURF2 PF05477.11 ORY32440.1 - 2.1 8.0 11.0 4.9 6.8 11.0 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) VIR_N PF15912.5 ORY32440.1 - 2.3 7.7 19.8 4.5 6.8 19.8 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal Retinal PF15449.6 ORY32440.1 - 3.2 5.4 20.7 5.1 4.7 20.7 1.3 1 0 0 1 1 1 0 Retinal protein Tim54 PF11711.8 ORY32440.1 - 4.1 6.1 10.8 6.8 5.4 10.8 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RPN2_C PF18004.1 ORY32440.1 - 4.1 7.3 18.4 8.4 6.3 18.4 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain TRAP_alpha PF03896.16 ORY32440.1 - 5.5 6.1 7.2 9.5 5.3 7.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Hamartin PF04388.12 ORY32440.1 - 5.9 5.4 11.9 8 5.0 11.9 1.2 1 0 0 1 1 1 0 Hamartin protein PBP_sp32 PF07222.12 ORY32440.1 - 6.7 6.1 10.4 12 5.3 10.4 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Nucleo_P87 PF07267.11 ORY32440.1 - 8 5.2 14.8 12 4.6 14.8 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CFEM PF05730.11 ORY32441.1 - 0.0062 16.6 0.1 0.023 14.8 0.1 2.0 1 0 0 1 1 1 1 CFEM domain Robl_LC7 PF03259.17 ORY32441.1 - 0.16 11.8 1.3 0.47 10.3 1.1 1.9 1 1 0 1 1 1 0 Roadblock/LC7 domain RIFIN PF02009.16 ORY32441.1 - 0.71 9.7 7.7 1 9.2 7.7 1.4 1 0 0 1 1 1 0 Rifin Mucin PF01456.17 ORY32442.1 - 0.00028 20.9 16.5 0.00029 20.8 16.5 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein RIFIN PF02009.16 ORY32442.1 - 0.056 13.3 3.0 0.058 13.3 3.0 1.1 1 0 0 1 1 1 0 Rifin FSA_C PF10479.9 ORY32442.1 - 0.088 10.9 10.9 0.1 10.8 10.9 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus TMEM154 PF15102.6 ORY32442.1 - 1.2 9.0 6.2 1.5 8.7 6.2 1.3 1 0 0 1 1 1 0 TMEM154 protein family Med3 PF11593.8 ORY32442.1 - 4.6 6.3 12.4 5 6.2 12.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pkinase PF00069.25 ORY32443.1 - 1e-69 234.9 0.0 1.2e-69 234.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY32443.1 - 7.5e-34 117.2 0.0 1e-33 116.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY32443.1 - 0.0021 17.1 0.3 0.004 16.2 0.3 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY32443.1 - 0.0025 17.2 0.2 0.0042 16.5 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY32443.1 - 0.01 15.8 0.1 0.092 12.6 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 ORY32444.1 - 6.7e-70 235.5 0.0 8.2e-70 235.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY32444.1 - 3e-31 108.7 0.0 4.3e-31 108.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY32444.1 - 0.0073 15.3 0.0 0.025 13.5 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY32444.1 - 0.026 13.9 0.0 0.053 12.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY32444.1 - 0.073 13.0 1.7 0.17 11.8 0.1 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Mito_carr PF00153.27 ORY32445.1 - 5.3e-55 183.3 6.5 5.1e-18 64.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S8 PF00082.22 ORY32446.1 - 2.6e-32 112.3 4.9 3.9e-32 111.7 4.9 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 ORY32446.1 - 2.8e-23 81.7 0.2 5.8e-23 80.7 0.2 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 ORY32446.1 - 0.00016 22.4 0.0 0.00032 21.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 ORY32446.1 - 0.033 14.7 0.2 0.06 13.8 0.2 1.4 1 0 0 1 1 1 0 N-terminal of Subtilase family zf-B_box PF00643.24 ORY32448.1 - 0.00013 22.0 11.3 0.00021 21.4 11.3 1.2 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 ORY32448.1 - 0.0035 17.6 6.6 0.0052 17.0 6.6 1.3 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-C3HC4_3 PF13920.6 ORY32448.1 - 0.13 12.1 6.1 0.23 11.3 6.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.21 ORY32448.1 - 0.97 9.7 10.0 2.2 8.6 10.0 1.6 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain DUF2009 PF09418.10 ORY32449.1 - 7.5e-212 704.3 0.1 8.5e-212 704.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) Oxysterol_BP PF01237.18 ORY32450.1 - 1.3e-49 169.0 0.7 5.4e-44 150.5 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein LRR_4 PF12799.7 ORY32452.1 - 1.4e-10 41.2 12.5 0.054 13.9 0.8 4.8 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY32452.1 - 4.9e-07 29.4 6.9 0.031 14.0 0.0 4.4 4 1 0 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 ORY32452.1 - 0.0018 18.5 10.9 36 5.5 0.0 7.3 4 3 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 ORY32452.1 - 0.0093 15.9 11.2 3.1 8.1 0.0 6.0 7 0 0 7 7 7 2 Leucine Rich repeat Adeno_PIX PF03955.14 ORY32452.1 - 0.84 9.8 5.2 0.54 10.4 1.3 2.3 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) LtrA PF06772.11 ORY32456.1 - 6.8e-31 107.8 12.2 6.8e-31 107.8 12.2 2.0 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) Ac76 PF05814.11 ORY32456.1 - 0.043 13.8 2.1 0.27 11.3 0.2 3.0 2 0 0 2 2 2 0 Orf76 (Ac76) Glyco_hydro_48 PF02011.15 ORY32456.1 - 0.16 10.5 0.0 0.23 9.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 48 Gly_transf_sug PF04488.15 ORY32457.1 - 2.1e-15 57.1 0.0 4e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Gb3_synth PF04572.12 ORY32457.1 - 0.00017 21.7 0.0 0.00027 21.1 0.0 1.4 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region HEAT PF02985.22 ORY32458.1 - 1.1e-15 56.3 12.0 0.2 12.0 0.0 10.1 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.6 ORY32458.1 - 2e-14 53.7 9.8 0.00064 20.1 0.1 7.1 4 2 3 7 7 7 6 HEAT repeats HEAT_EZ PF13513.6 ORY32458.1 - 1.2e-09 38.5 18.4 0.00036 21.0 0.0 9.2 8 1 2 10 10 10 1 HEAT-like repeat Cnd1 PF12717.7 ORY32458.1 - 3.8e-07 30.3 0.3 0.3 11.1 0.1 6.2 4 1 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 ORY32458.1 - 9.1e-06 25.4 0.0 0.73 9.4 0.0 4.9 5 1 0 5 5 5 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 ORY32458.1 - 0.0005 20.6 0.0 8.2 7.1 0.0 4.9 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region IFRD PF05004.13 ORY32458.1 - 0.00091 18.4 0.1 0.83 8.7 0.2 3.9 4 1 1 5 5 5 1 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 ORY32458.1 - 0.005 15.5 0.0 0.012 14.2 0.0 1.5 1 0 0 1 1 1 1 Adaptin N terminal region TIP120 PF08623.10 ORY32458.1 - 0.019 14.7 0.1 0.48 10.2 0.0 3.2 4 0 0 4 4 4 0 TATA-binding protein interacting (TIP20) Cnd3 PF12719.7 ORY32458.1 - 0.089 12.0 0.4 0.19 10.9 0.4 1.5 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain AAA_lid_8 PF17868.1 ORY32462.1 - 0.088 12.7 0.4 2.5 8.1 0.0 2.6 2 0 0 2 2 2 0 AAA lid domain Pkinase PF00069.25 ORY32463.1 - 0.00034 20.1 0.0 0.00034 20.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 ORY32464.1 - 5e-64 216.2 0.0 5.8e-64 216.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY32464.1 - 9.6e-34 116.8 0.0 1.2e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY32464.1 - 2.7e-06 26.9 0.1 0.00051 19.4 0.1 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 ORY32464.1 - 0.015 15.2 0.5 0.13 12.2 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY32464.1 - 0.016 14.2 0.0 0.2 10.6 0.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 ORY32464.1 - 0.056 13.0 0.3 0.13 11.9 0.2 1.4 1 1 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 ORY32464.1 - 0.2 10.4 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Peptidase_S8 PF00082.22 ORY32465.1 - 4.6e-32 111.5 5.4 7.3e-32 110.8 5.4 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 ORY32465.1 - 2.3e-16 59.6 2.8 1.1e-14 54.2 2.8 2.5 1 1 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 ORY32465.1 - 1.9e-06 28.6 0.0 3.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase S8 pro-domain LuxS PF02664.15 ORY32465.1 - 0.033 13.9 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 S-Ribosylhomocysteinase (LuxS) Peptidase_S8_N PF16361.5 ORY32465.1 - 0.09 13.3 0.1 0.17 12.4 0.1 1.4 1 0 0 1 1 1 0 N-terminal of Subtilase family DUF2306 PF10067.9 ORY32466.1 - 0.00018 21.8 7.0 0.00033 20.9 7.0 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) 7tm_1 PF00001.21 ORY32467.1 - 1.2e-21 77.2 9.2 1.3e-21 77.1 8.5 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 ORY32468.1 - 2.6e-16 59.8 7.0 2.6e-16 59.8 7.0 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) PGA_cap PF09587.10 ORY32469.1 - 0.081 12.4 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap FERM_F2 PF18377.1 ORY32469.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 FERM F2 acyl-CoA binding protein-like domain Spc7 PF08317.11 ORY32470.1 - 0.0043 16.0 13.2 0.0043 16.0 13.2 2.8 3 0 0 3 3 3 1 Spc7 kinetochore protein Tub PF01167.18 ORY32470.1 - 0.018 14.8 0.0 0.04 13.7 0.0 1.5 1 1 0 1 1 1 0 Tub family FUSC PF04632.12 ORY32470.1 - 1.4 7.4 8.6 2.3 6.6 8.6 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Nitroreductase PF00881.24 ORY32471.1 - 7.5e-18 65.2 0.2 2.4e-15 57.0 0.2 2.2 1 1 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 ORY32471.1 - 5.4e-05 22.9 0.0 0.01 15.4 0.0 2.2 2 0 0 2 2 2 2 Putative TM nitroreductase Peptidase_S8 PF00082.22 ORY32474.1 - 2.9e-31 108.8 3.1 6.2e-31 107.8 3.1 1.5 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 ORY32474.1 - 1.2e-20 73.3 0.5 2.1e-20 72.5 0.5 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 ORY32474.1 - 1.1e-07 32.5 0.0 5.8e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 Peptidase S8 pro-domain SKG6 PF08693.10 ORY32474.1 - 0.0011 18.3 0.2 0.0011 18.3 0.2 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Peptidase_S8_N PF16361.5 ORY32474.1 - 0.057 13.9 0.2 0.093 13.2 0.2 1.3 1 0 0 1 1 1 0 N-terminal of Subtilase family P_proprotein PF01483.20 ORY32475.1 - 3.3e-24 84.7 0.1 5.9e-24 83.9 0.1 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain Peptidase_S8 PF00082.22 ORY32475.1 - 5.7e-20 71.8 1.6 1.4e-19 70.5 1.5 1.6 1 1 0 1 1 1 1 Subtilase family S8_pro-domain PF16470.5 ORY32475.1 - 1e-08 35.8 0.0 2.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 ORY32475.1 - 0.0046 17.5 0.1 0.0082 16.6 0.1 1.4 1 0 0 1 1 1 1 N-terminal of Subtilase family RVT_1 PF00078.27 ORY32476.1 - 1.2e-06 28.3 0.0 1.8e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Peptidase_S8 PF00082.22 ORY32478.1 - 1.6e-28 99.8 4.5 1.7e-18 66.9 1.0 2.4 1 1 1 2 2 2 2 Subtilase family P_proprotein PF01483.20 ORY32478.1 - 1.7e-25 88.9 0.5 3.1e-25 88.0 0.5 1.4 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 ORY32478.1 - 6.6e-07 30.0 0.0 1.5e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase S8 pro-domain Peptidase_S8 PF00082.22 ORY32479.1 - 6e-40 137.4 4.4 9e-40 136.8 4.4 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 ORY32479.1 - 7.9e-17 61.1 0.1 2.3e-16 59.6 0.1 1.8 1 0 0 1 1 1 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 ORY32479.1 - 1.9e-05 25.4 0.3 4.6e-05 24.1 0.3 1.7 1 0 0 1 1 1 1 Peptidase S8 pro-domain FixQ PF05545.11 ORY32479.1 - 0.021 14.8 0.4 0.045 13.7 0.4 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ YajC PF02699.15 ORY32479.1 - 0.026 14.4 0.9 0.24 11.3 1.3 2.3 2 0 0 2 2 2 0 Preprotein translocase subunit Peptidase_S8_N PF16361.5 ORY32479.1 - 0.05 14.1 0.1 0.091 13.2 0.1 1.4 1 0 0 1 1 1 0 N-terminal of Subtilase family Pet191_N PF10203.9 ORY32483.1 - 1.5 9.1 14.5 1.3 9.3 0.7 3.2 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Glucos_trans_II PF14264.6 ORY32484.1 - 4.2 6.7 13.3 2.7 7.2 9.9 1.9 2 0 0 2 2 2 0 Glucosyl transferase GtrII Helicase_C_2 PF13307.6 ORY32485.1 - 2.9e-56 190.3 0.0 6.5e-56 189.2 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 ORY32485.1 - 7.8e-54 181.9 0.5 1.3e-53 181.2 0.5 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.15 ORY32485.1 - 0.0021 18.1 0.2 1.2 9.1 0.2 2.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY32485.1 - 0.02 14.7 0.0 1.9 8.2 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase Nuc_deoxyri_tr2 PF15891.5 ORY32485.1 - 0.088 13.1 0.1 10 6.5 0.2 2.4 2 0 0 2 2 2 0 Nucleoside 2-deoxyribosyltransferase like Glyco_hydro_20 PF00728.22 ORY32487.1 - 7.3e-73 246.0 0.0 1.1e-72 245.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 ORY32487.1 - 2.7e-07 31.4 0.1 6.3e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 ORY32487.1 - 5.9e-06 27.0 0.0 4.4e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like DnaJ_C PF01556.18 ORY32488.1 - 1.3e-32 113.0 0.1 3.2e-32 111.7 0.1 1.7 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORY32488.1 - 1.4e-29 102.0 2.1 2.5e-29 101.2 2.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ORY32488.1 - 9.5e-16 57.9 17.9 1.8e-15 57.1 17.9 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 ORY32488.1 - 0.083 12.9 9.0 0.081 12.9 0.6 2.4 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 ORY32488.1 - 4 7.5 8.9 9 6.4 2.1 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA WD40 PF00400.32 ORY32489.1 - 2.9e-104 338.0 52.3 1.2e-09 38.7 0.1 13.3 13 0 0 13 13 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY32489.1 - 2.4e-34 117.5 11.3 0.002 18.4 0.1 11.6 1 1 11 12 12 12 9 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY32489.1 - 7.1e-21 74.5 20.3 0.021 13.5 0.0 9.7 3 3 6 10 10 10 8 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY32489.1 - 3e-19 69.5 5.0 0.0016 17.8 0.1 6.8 3 2 3 6 6 6 4 WD40-like domain Ge1_WD40 PF16529.5 ORY32489.1 - 2.8e-16 59.4 22.3 0.00039 19.5 0.5 8.4 1 1 5 6 6 6 5 WD40 region of Ge1, enhancer of mRNA-decapping protein TIR_2 PF13676.6 ORY32489.1 - 2.3e-13 50.8 0.2 5.9e-12 46.2 0.0 2.9 3 0 0 3 3 2 1 TIR domain PD40 PF07676.12 ORY32489.1 - 2.5e-08 33.7 6.4 4.4 7.4 0.0 8.2 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat NACHT PF05729.12 ORY32489.1 - 4.4e-08 33.2 0.4 1.5e-06 28.2 0.4 2.4 1 1 0 1 1 1 1 NACHT domain CDtoxinA PF03498.14 ORY32489.1 - 1.9e-06 27.5 2.2 0.05 13.2 0.1 5.2 3 2 2 5 5 5 1 Cytolethal distending toxin A/C domain KAP_NTPase PF07693.14 ORY32489.1 - 0.00025 20.4 0.4 0.1 11.8 0.3 2.3 1 1 1 2 2 2 2 KAP family P-loop domain AAA_16 PF13191.6 ORY32489.1 - 0.0033 17.8 0.1 0.012 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain TIR PF01582.20 ORY32489.1 - 0.012 15.5 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 TIR domain CNH PF00780.22 ORY32489.1 - 0.013 15.2 1.7 18 4.8 0.0 5.3 7 1 1 8 8 8 0 CNH domain AAA_7 PF12775.7 ORY32489.1 - 0.016 14.8 0.1 0.099 12.1 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Cytochrom_D1 PF02239.16 ORY32489.1 - 0.059 11.9 1.0 44 2.4 0.0 4.0 2 2 1 4 4 4 0 Cytochrome D1 heme domain AAA_30 PF13604.6 ORY32489.1 - 0.12 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Proteasome_A_N PF10584.9 ORY32489.1 - 0.59 9.9 6.8 50 3.7 0.1 5.3 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Cyclin PF08613.11 ORY32490.1 - 0.082 13.3 0.1 0.2 12.0 0.1 1.6 1 0 0 1 1 1 0 Cyclin BUD22 PF09073.10 ORY32490.1 - 2.3 7.4 11.2 2.8 7.2 11.2 1.1 1 0 0 1 1 1 0 BUD22 LRR_4 PF12799.7 ORY32687.1 - 0.00048 20.5 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY32687.1 - 0.00058 19.6 0.1 0.002 17.9 0.0 1.8 2 0 0 2 2 2 1 Leucine rich repeat Orthoreo_P10 PF07204.11 ORY32687.1 - 0.012 15.5 0.5 0.027 14.4 0.5 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 stn_TNFRSF12A PF12191.8 ORY32687.1 - 0.014 15.7 1.2 0.025 14.8 1.2 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain LRR_1 PF00560.33 ORY32687.1 - 0.017 15.6 3.6 0.69 10.7 0.0 3.6 4 1 0 4 4 4 0 Leucine Rich Repeat Herpes_gE PF02480.16 ORY32687.1 - 0.11 11.2 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF3421 PF11901.8 ORY32690.1 - 2.9e-20 72.4 2.8 3.8e-07 30.1 0.1 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) LRR_4 PF12799.7 ORY32691.1 - 0.00048 20.4 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY32691.1 - 0.00068 19.4 0.1 0.0021 17.8 0.0 1.8 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 ORY32691.1 - 0.0099 16.3 2.9 0.73 10.6 0.0 3.7 4 1 0 4 4 4 1 Leucine Rich Repeat Orthoreo_P10 PF07204.11 ORY32691.1 - 0.013 15.4 0.5 0.029 14.3 0.5 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 stn_TNFRSF12A PF12191.8 ORY32691.1 - 0.015 15.5 1.1 0.026 14.7 1.1 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Shisa PF13908.6 ORY32691.1 - 0.062 13.6 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Herpes_gE PF02480.16 ORY32691.1 - 0.12 11.1 0.1 0.17 10.6 0.1 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Alpha_GJ PF03229.13 ORY32691.1 - 1.5 9.4 21.9 0.4 11.2 18.2 1.8 2 0 0 2 2 2 0 Alphavirus glycoprotein J GRDP-like PF07173.12 ORY32692.1 - 6.8e-31 107.8 1.8 6.1e-20 72.3 0.0 2.5 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like zf-DNA_Pol PF08996.10 ORY32692.1 - 0.0074 16.1 0.3 0.013 15.3 0.3 1.3 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger SH3_9 PF14604.6 ORY32692.1 - 0.0077 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ubiq-Cytc-red_N PF09165.10 ORY32692.1 - 0.12 13.2 2.9 0.36 11.7 2.9 1.8 1 0 0 1 1 1 0 Ubiquinol-cytochrome c reductase 8 kDa, N-terminal Zip PF02535.22 ORY32693.1 - 3.6e-17 62.6 19.3 5.2e-17 62.1 4.3 2.6 2 1 0 2 2 2 2 ZIP Zinc transporter Piwi PF02171.17 ORY32694.1 - 1.1e-65 221.9 0.0 1e-64 218.7 0.0 2.1 2 0 0 2 2 2 1 Piwi domain ArgoN PF16486.5 ORY32694.1 - 7.9e-14 52.4 0.0 1.5e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 ORY32694.1 - 1.1e-12 47.9 0.0 1.9e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoL2 PF16488.5 ORY32694.1 - 1.3e-07 31.8 0.0 2.8e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoL1 PF08699.10 ORY32694.1 - 3e-06 26.8 0.0 7.1e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain Acetyltransf_10 PF13673.7 ORY32694.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MitMem_reg PF13012.6 ORY32695.1 - 1.1e-22 80.5 0.6 1.3e-22 80.4 0.6 1.1 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function RsgA_GTPase PF03193.16 ORY32697.1 - 0.0063 16.4 0.0 0.059 13.3 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase Septin PF00735.18 ORY32697.1 - 0.04 13.2 0.0 0.85 8.8 0.0 2.1 2 0 0 2 2 2 0 Septin Ndc80_HEC PF03801.13 ORY32697.1 - 0.048 13.3 0.1 2.2 7.9 0.0 2.1 2 0 0 2 2 2 0 HEC/Ndc80p family Croc_4 PF17691.1 ORY32698.1 - 0.071 13.2 0.5 0.14 12.2 0.5 1.4 1 0 0 1 1 1 0 Contingent replication of cDNA 4 DUF697 PF05128.12 ORY32698.1 - 0.14 11.8 0.8 0.31 10.8 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF697) RsgA_GTPase PF03193.16 ORY32698.1 - 0.14 12.0 0.0 6.4 6.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase zf-C2H2_jaz PF12171.8 ORY32699.1 - 0.00082 19.6 3.0 0.76 10.1 0.1 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf_ZIC PF18366.1 ORY32699.1 - 0.0034 17.4 1.2 0.0034 17.4 1.2 2.5 2 1 0 2 2 2 1 Zic proteins zinc finger domain zf-C2H2_4 PF13894.6 ORY32699.1 - 0.66 11.0 17.1 1.7 9.7 0.2 4.0 3 2 1 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY32699.1 - 4.9 7.8 17.9 1.2 9.7 1.2 4.0 3 2 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 ORY32701.1 - 6.3e-06 26.3 3.8 0.15 12.4 0.0 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY32701.1 - 0.01 16.2 2.3 3.5 8.1 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf_ZIC PF18366.1 ORY32701.1 - 0.024 14.7 0.0 0.024 14.7 0.0 2.8 2 1 1 3 3 3 0 Zic proteins zinc finger domain zf-C2H2 PF00096.26 ORY32701.1 - 0.12 12.9 15.6 1.9 9.1 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type FOXP-CC PF16159.5 ORY32701.1 - 0.43 11.3 11.5 2.3 8.9 5.5 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 ORY32701.1 - 0.45 11.5 15.4 7.4 7.7 0.2 3.5 3 1 0 3 3 3 0 C2H2-type zinc finger Alpha-amylase_C PF02806.18 ORY32704.1 - 3.9e-26 91.4 0.1 8e-26 90.4 0.1 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 ORY32704.1 - 7.8e-18 64.6 0.0 1.6e-17 63.6 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 ORY32704.1 - 2.5e-14 53.6 0.0 1.3e-10 41.4 0.0 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain S36_mt PF10937.8 ORY32706.1 - 0.11 14.1 0.9 0.16 13.5 0.9 1.2 1 0 0 1 1 1 0 Ribosomal protein S36, mitochondrial DUF4834 PF16118.5 ORY32706.1 - 0.16 12.9 0.0 0.36 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) zf-CCHC_6 PF15288.6 ORY32706.1 - 0.18 11.6 10.2 0.17 11.8 1.6 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 ORY32706.1 - 0.47 10.2 5.5 0.3 10.9 0.5 2.7 3 0 0 3 3 3 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.19 ORY32706.1 - 0.6 10.5 10.1 1.4 9.3 9.9 1.7 1 1 0 1 1 1 0 DnaJ central domain HIPIP PF01355.17 ORY32706.1 - 6.2 7.2 9.4 2.5 8.5 1.4 3.0 2 1 1 3 3 3 0 High potential iron-sulfur protein DUF5338 PF17273.2 ORY32708.1 - 0.097 12.8 0.1 0.097 12.8 0.1 2.7 4 0 0 4 4 4 0 Family of unknown function (DUF5338) Presenilin PF01080.17 ORY32708.1 - 0.24 10.1 4.3 0.45 9.2 4.3 1.4 1 0 0 1 1 1 0 Presenilin MRPL52 PF18699.1 ORY32708.1 - 1 9.6 10.3 0.39 10.9 0.2 2.8 2 0 0 2 2 2 0 Mitoribosomal protein mL52 KI67R PF08065.12 ORY32708.1 - 2.7 8.5 13.0 9.3 6.8 0.4 2.4 2 0 0 2 2 2 0 KI67R (NUC007) repeat DUF2321 PF10083.9 ORY32709.1 - 0.025 14.2 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) DEAD PF00270.29 ORY32710.1 - 9.3e-33 113.4 0.1 1.5e-32 112.8 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY32710.1 - 1.6e-26 92.8 0.0 3.6e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 ORY32710.1 - 0.00039 20.2 0.1 0.00071 19.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain CMS1 PF14617.6 ORY32710.1 - 0.09 12.1 0.0 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit CIDE-N PF02017.15 ORY32710.1 - 0.11 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 CIDE-N domain AAA_22 PF13401.6 ORY32710.1 - 0.15 12.3 0.5 0.74 10.1 0.3 2.2 1 1 1 2 2 2 0 AAA domain DUF3997 PF13162.6 ORY32711.1 - 0.017 15.4 0.3 0.022 15.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3997) LAG1-DNAbind PF09271.11 ORY32711.1 - 0.081 13.5 1.9 0.11 13.1 1.9 1.3 1 0 0 1 1 1 0 LAG1, DNA binding DUF3176 PF11374.8 ORY32712.1 - 0.1 12.8 0.3 0.1 12.8 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) MARVEL PF01284.23 ORY32712.1 - 1.5 8.8 20.1 0.071 13.1 7.3 3.0 1 1 0 2 2 2 0 Membrane-associating domain RhoGEF PF00621.20 ORY32713.1 - 6.2e-27 95.0 5.0 1.2e-26 94.0 5.0 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.6 ORY32713.1 - 2.4e-17 63.3 0.0 4.5e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 ORY32713.1 - 7.6e-14 51.7 0.1 1.2e-12 47.9 0.0 2.5 2 0 0 2 2 2 1 CDC24 Calponin TIR_2 PF13676.6 ORY32713.1 - 4.6e-10 40.1 0.0 1.1e-09 38.9 0.0 1.6 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 ORY32713.1 - 0.0042 16.9 0.0 0.0099 15.7 0.0 1.5 1 0 0 1 1 1 1 TIR domain RhoGEF PF00621.20 ORY32714.1 - 3.9e-26 92.4 5.4 7.3e-26 91.5 5.4 1.5 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.11 ORY32714.1 - 1.1e-18 67.3 0.1 4e-18 65.4 0.1 2.0 1 0 0 1 1 1 1 CDC24 Calponin PH_10 PF15411.6 ORY32714.1 - 1.4e-17 64.1 0.1 3.1e-17 63.0 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RICH PF05062.12 ORY32714.1 - 0.078 13.3 4.3 1.8 9.0 0.4 2.5 2 0 0 2 2 2 0 RICH domain zf-CCHC PF00098.23 ORY32715.1 - 6.2e-06 26.0 1.3 6.2e-06 26.0 1.3 2.1 3 0 0 3 3 3 1 Zinc knuckle Retrotran_gag_2 PF14223.6 ORY32715.1 - 0.0051 16.5 0.1 0.01 15.5 0.1 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 ORY32715.1 - 0.0081 16.0 0.1 0.023 14.5 0.1 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain TIR_2 PF13676.6 ORY32716.1 - 1.6e-11 44.9 0.0 3.9e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 TIR domain Motile_Sperm PF00635.26 ORY32716.1 - 1.3e-07 31.4 0.0 2.6e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain TIR PF01582.20 ORY32716.1 - 0.0087 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 TIR domain UNC-50 PF05216.13 ORY32716.1 - 0.063 12.8 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 UNC-50 family ASH PF15780.5 ORY32716.1 - 0.15 12.3 0.1 0.35 11.1 0.1 1.6 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Sel1 PF08238.12 ORY32717.1 - 7.1e-40 134.5 22.5 2.6e-11 43.8 0.3 6.1 6 0 0 6 6 6 5 Sel1 repeat Pkinase PF00069.25 ORY32717.1 - 7.9e-37 127.0 0.0 1.2e-36 126.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY32717.1 - 1.5e-31 109.7 0.0 2.4e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY32717.1 - 0.073 13.0 0.2 0.17 11.8 0.2 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Membr_traf_MHD PF10540.9 ORY32717.1 - 0.097 12.8 0.5 0.2 11.8 0.5 1.4 1 0 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain AIRC PF00731.20 ORY32718.1 - 0.018 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 AIR carboxylase Spheroidin PF05541.12 ORY32718.1 - 0.12 10.2 0.0 0.16 9.8 0.0 1.1 1 0 0 1 1 1 0 Entomopoxvirus spheroidin protein Polyketide_cyc2 PF10604.9 ORY32720.1 - 2.7e-07 30.9 0.3 1.8e-06 28.2 0.3 2.2 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 ORY32720.1 - 0.00098 19.3 0.1 0.0023 18.2 0.1 1.9 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Lactamase_B_2 PF12706.7 ORY32721.1 - 3.2e-28 98.6 0.3 4.8e-28 98.1 0.3 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY32721.1 - 9.5e-07 29.0 0.6 2.1e-06 27.9 0.6 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 ORY32721.1 - 0.0018 17.8 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain FSA_C PF10479.9 ORY32722.1 - 3.9 5.5 25.1 5.3 5.1 25.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus HsbA PF12296.8 ORY32724.1 - 0.12 12.8 10.1 0.15 12.4 5.6 2.2 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Myb_DNA-bind_4 PF13837.6 ORY32725.1 - 0.24 11.8 0.0 0.24 11.8 0.0 2.7 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DMRT-like PF15791.5 ORY32725.1 - 1 9.8 4.7 0.27 11.7 0.6 2.1 2 1 1 3 3 3 0 Doublesex-and mab-3-related transcription factor C1 and C2 RR_TM4-6 PF06459.12 ORY32725.1 - 1.9 8.2 10.6 2.9 7.7 10.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 LRR_8 PF13855.6 ORY32728.1 - 2.5e-11 43.2 5.5 7.2e-10 38.5 0.5 2.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY32728.1 - 3.3e-09 36.9 5.0 5.9e-05 23.4 0.1 2.5 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY32728.1 - 5.2e-05 23.3 0.6 1.9 9.4 0.0 4.3 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 ORY32728.1 - 0.00077 19.3 4.4 2.5 8.4 0.1 3.6 3 0 0 3 3 3 2 Leucine Rich repeat LRR_5 PF13306.6 ORY32728.1 - 0.04 13.9 0.1 0.04 13.9 0.1 2.4 2 1 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) JAB PF01398.21 ORY32729.1 - 4.7e-18 65.3 0.2 8.8e-18 64.4 0.2 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease BRCC36_C PF18110.1 ORY32729.1 - 1.9e-13 50.3 0.2 3.2e-13 49.6 0.2 1.4 1 0 0 1 1 1 1 BRCC36 C-terminal helical domain Prok-JAB PF14464.6 ORY32729.1 - 1.2e-09 37.9 0.1 1.9e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MCM PF00493.23 ORY32730.1 - 2.5e-99 330.9 0.0 3.4e-99 330.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY32730.1 - 9e-37 125.7 1.5 1.8e-36 124.8 1.5 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORY32730.1 - 1.7e-27 95.7 0.2 3.8e-27 94.5 0.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 ORY32730.1 - 9.4e-12 45.4 0.0 7.4e-11 42.6 0.0 2.3 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 ORY32730.1 - 5.4e-07 29.7 0.0 1.5e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ORY32730.1 - 2.5e-06 27.0 0.0 0.00062 19.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 ORY32730.1 - 0.00031 20.6 0.0 0.0024 17.7 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 ORY32730.1 - 0.002 17.9 0.0 3.1 7.5 0.0 2.9 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_16 PF13191.6 ORY32730.1 - 0.0094 16.4 0.0 0.047 14.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 ORY32730.1 - 0.067 13.1 0.0 8 6.3 0.0 2.5 1 1 1 2 2 2 0 NTPase Ank_2 PF12796.7 ORY32731.1 - 9e-24 83.9 2.3 9.2e-08 32.6 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY32731.1 - 7.2e-15 55.1 1.1 2.6e-05 24.7 0.0 5.2 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY32731.1 - 2.2e-11 42.9 0.7 0.015 15.8 0.0 6.8 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 ORY32731.1 - 6.5e-10 39.1 4.5 0.099 13.0 0.0 6.0 1 1 6 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY32731.1 - 7e-06 26.3 4.3 4.9 7.8 0.0 5.7 6 0 0 6 6 6 2 Ankyrin repeat Cytochrom_C PF00034.21 ORY32732.1 - 7.6e-12 46.2 0.0 9.2e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 ORY32732.1 - 5.4e-06 26.6 0.7 3.7e-05 24.0 0.7 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 ORY32732.1 - 0.0057 16.4 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 Cytochrome c-550 domain Skp1_POZ PF03931.15 ORY32734.1 - 7e-12 45.3 0.1 1.9e-11 43.9 0.0 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.31 ORY32734.1 - 0.00023 21.4 0.1 0.00037 20.7 0.1 1.3 1 1 0 1 1 1 1 BTB/POZ domain DUF4085 PF13315.6 ORY32734.1 - 0.076 12.6 0.1 0.13 11.9 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4085) Rif1_N PF12231.8 ORY32734.1 - 0.086 11.8 0.0 0.095 11.7 0.0 1.0 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal NYD-SP28 PF14772.6 ORY32735.1 - 1.2e-23 83.0 11.1 1.2e-23 83.0 11.1 5.1 3 1 3 6 6 6 1 Sperm tail NYD-SP28_assoc PF14775.6 ORY32735.1 - 3.1e-19 68.8 2.1 3.1e-19 68.8 2.1 4.4 4 1 1 5 5 5 1 Sperm tail C-terminal domain DUF4854 PF16146.5 ORY32735.1 - 2.3 8.6 12.0 0.15 12.4 2.9 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF4854) Nucleocapsid-N PF11030.8 ORY32737.1 - 0.049 13.6 0.2 0.071 13.1 0.2 1.2 1 0 0 1 1 1 0 Nucleocapsid protein N EIF_2_alpha PF07541.12 ORY32738.1 - 4.8e-42 142.7 0.1 9.4e-42 141.8 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 ORY32738.1 - 1.9e-15 57.0 0.8 5.3e-15 55.5 0.8 1.8 1 0 0 1 1 1 1 S1 RNA binding domain Spindle_Spc25 PF08234.12 ORY32738.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Chromosome segregation protein Spc25 Ten1_2 PF15490.6 ORY32739.1 - 1.4e-24 86.1 0.0 1.7e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit DtxR PF18357.1 ORY32739.1 - 0.29 10.8 1.2 0.48 10.1 1.2 1.4 1 0 0 1 1 1 0 Diphteria toxin repressor SH3 domain Sel1 PF08238.12 ORY32740.1 - 6.7e-37 125.1 18.7 2.4e-06 28.0 0.2 9.1 10 1 0 10 10 9 6 Sel1 repeat TPR_6 PF13174.6 ORY32740.1 - 3.9e-10 39.7 18.2 0.37 11.5 0.0 8.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY32740.1 - 5.9e-09 36.4 18.0 0.15 12.7 4.5 6.1 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 ORY32740.1 - 1.8e-05 24.4 9.5 0.41 10.8 0.0 6.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY32740.1 - 5.1e-05 23.8 4.6 1.6 9.8 0.0 6.1 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY32740.1 - 0.026 14.2 8.1 5 6.9 0.2 5.5 7 0 0 7 7 7 0 TPR repeat TPR_10 PF13374.6 ORY32740.1 - 0.038 13.9 4.4 0.053 13.4 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY32740.1 - 0.057 13.3 0.1 0.057 13.3 0.1 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat DUF627 PF04781.12 ORY32740.1 - 0.063 13.3 0.0 0.46 10.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF627) TPR_17 PF13431.6 ORY32740.1 - 0.094 13.1 5.1 57 4.4 0.1 4.5 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY32740.1 - 0.22 11.7 0.1 0.22 11.7 0.1 8.0 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY32740.1 - 0.29 11.4 9.9 1.3 9.3 0.2 4.2 5 1 1 6 6 6 0 Tetratricopeptide repeat Apt1 PF10351.9 ORY32741.1 - 9 5.0 17.4 17 4.1 17.4 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain HET PF06985.11 ORY32742.1 - 6.5e-15 55.8 1.6 1.3e-14 54.8 1.6 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ZZ PF00569.17 ORY32742.1 - 4.3e-05 23.2 10.9 0.00011 21.9 10.9 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type RPAP3_C PF13877.6 ORY32742.1 - 0.034 14.7 0.0 0.68 10.5 0.0 2.9 3 0 0 3 3 3 0 Potential Monad-binding region of RPAP3 C1_1 PF00130.22 ORY32742.1 - 0.51 10.3 9.9 0.45 10.4 6.9 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) G-alpha PF00503.20 ORY32743.1 - 5e-119 397.6 1.9 5.9e-119 397.4 1.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY32743.1 - 1.3e-14 54.0 4.1 2.3e-10 40.2 0.3 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY32743.1 - 0.0011 18.3 3.8 0.041 13.2 0.2 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY32743.1 - 0.003 17.8 0.1 1.7 8.8 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 ORY32743.1 - 0.011 15.5 0.4 0.018 14.8 0.1 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 ORY32743.1 - 0.029 14.1 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-CHC2 PF01807.20 ORY32743.1 - 0.044 13.6 0.2 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 CHC2 zinc finger MMR_HSR1 PF01926.23 ORY32743.1 - 0.058 13.5 0.1 4.1 7.5 0.0 2.6 1 1 1 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 ORY32744.1 - 4.4e-41 140.4 0.0 1e-40 139.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 ORY32744.1 - 9.3e-19 67.1 0.1 1.8e-18 66.2 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 ORY32744.1 - 1.2e-10 41.0 0.4 3.2e-10 39.6 0.4 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 ORY32744.1 - 4.2e-05 23.7 0.0 0.00014 22.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 ORY32744.1 - 5.4e-05 23.6 0.1 0.024 15.0 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 ORY32744.1 - 0.00011 22.0 0.0 0.00025 20.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ORY32744.1 - 0.00025 21.0 0.1 0.0016 18.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY32744.1 - 0.0016 18.8 0.4 0.16 12.2 0.4 2.6 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 ORY32744.1 - 0.0031 17.0 0.0 0.044 13.2 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_11 PF13086.6 ORY32744.1 - 0.0037 17.1 0.5 0.12 12.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 ORY32744.1 - 0.014 14.8 0.0 0.041 13.2 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI JIP_LZII PF16471.5 ORY32744.1 - 0.029 14.5 3.6 0.073 13.3 3.6 1.7 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II ATPase PF06745.13 ORY32744.1 - 0.036 13.4 2.2 0.11 11.8 0.0 2.6 3 0 0 3 3 3 0 KaiC AAA_33 PF13671.6 ORY32744.1 - 0.038 14.2 0.0 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ORY32744.1 - 0.042 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 ORY32744.1 - 0.056 13.0 0.0 0.12 11.9 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 ORY32744.1 - 0.074 12.8 0.4 0.19 11.4 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 ORY32744.1 - 0.079 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 ORY32744.1 - 0.08 12.7 0.0 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.13 ORY32744.1 - 0.094 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Prot_ATP_OB_N PF17758.1 ORY32744.1 - 0.17 11.6 0.0 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain MIS13 PF08202.11 ORY32745.1 - 1.7e-31 109.7 0.2 1.7e-31 109.7 0.2 2.1 1 1 0 2 2 2 1 Mis12-Mtw1 protein family UPF0242 PF06785.11 ORY32745.1 - 0.075 13.1 0.5 0.15 12.2 0.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Glyco_hydro_99 PF16317.5 ORY32747.1 - 0.14 11.2 0.1 0.24 10.5 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 99 ABC_tran PF00005.27 ORY32748.1 - 3e-26 92.5 0.0 5e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 ORY32748.1 - 7e-11 41.9 12.4 1.3e-10 41.1 12.4 1.4 1 0 0 1 1 1 1 ABC-2 type transporter RsgA_GTPase PF03193.16 ORY32748.1 - 0.0011 18.9 0.1 0.0021 18.0 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 ORY32748.1 - 0.0047 16.9 0.1 0.0091 15.9 0.1 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain SMC_N PF02463.19 ORY32748.1 - 0.0055 16.2 0.0 0.016 14.7 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORY32748.1 - 0.0076 16.8 0.0 0.011 16.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain TrwB_AAD_bind PF10412.9 ORY32748.1 - 0.009 15.0 0.0 0.014 14.3 0.0 1.1 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 ORY32748.1 - 0.0097 16.3 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase T2SSE PF00437.20 ORY32748.1 - 0.014 14.4 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 ORY32748.1 - 0.029 14.6 0.1 0.077 13.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORY32748.1 - 0.045 13.3 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 ORY32748.1 - 0.049 12.5 0.0 0.075 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.6 ORY32748.1 - 0.062 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 ORY32748.1 - 0.086 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ORY32748.1 - 0.087 12.6 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 ORY32748.1 - 0.12 12.3 0.3 0.31 11.0 0.1 1.7 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 ORY32748.1 - 0.14 12.3 0.1 0.3 11.2 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATPase_2 PF01637.18 ORY32748.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 ORY32748.1 - 0.21 11.3 0.3 0.52 10.0 0.1 1.7 2 0 0 2 2 2 0 AAA domain LapA_dom PF06305.11 ORY32748.1 - 0.42 10.5 2.2 15 5.5 0.1 2.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain LRR_1 PF00560.33 ORY32749.1 - 0.008 16.6 0.8 1.2 9.9 0.0 3.9 3 1 0 3 3 3 1 Leucine Rich Repeat DAP10 PF07213.11 ORY32749.1 - 0.077 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 DAP10 membrane protein LRR_8 PF13855.6 ORY32749.1 - 0.082 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Leucine rich repeat LRR_8 PF13855.6 ORY32750.1 - 0.01 15.6 0.0 0.028 14.2 0.0 1.8 1 0 0 1 1 1 1 Leucine rich repeat Orthoreo_P10 PF07204.11 ORY32750.1 - 0.02 14.9 1.6 0.036 14.0 1.6 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Alpha_GJ PF03229.13 ORY32750.1 - 0.029 14.9 20.6 0.048 14.2 20.6 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J Herpes_gE PF02480.16 ORY32750.1 - 0.037 12.8 0.5 0.066 11.9 0.1 1.5 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E GRP PF07172.11 ORY32750.1 - 0.037 14.7 2.0 0.037 14.7 2.0 2.4 1 1 1 2 2 2 0 Glycine rich protein family LRR_4 PF12799.7 ORY32750.1 - 0.056 13.9 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) MGC-24 PF05283.11 ORY32750.1 - 0.26 11.7 4.8 0.39 11.2 4.8 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Stevor PF17410.2 ORY32750.1 - 0.89 9.0 3.1 1.2 8.6 3.1 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame ABC_tran PF00005.27 ORY32751.1 - 3.1e-25 89.3 0.0 6.5e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 ORY32751.1 - 7e-12 45.2 12.2 7e-12 45.2 12.2 1.9 2 0 0 2 2 1 1 ABC-2 type transporter T2SSE PF00437.20 ORY32751.1 - 0.00056 19.0 0.1 0.00083 18.5 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_25 PF13481.6 ORY32751.1 - 0.0015 18.2 0.3 0.0053 16.4 0.1 1.9 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 ORY32751.1 - 0.0021 18.0 0.2 0.004 17.1 0.2 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain RNA_helicase PF00910.22 ORY32751.1 - 0.014 15.8 0.1 0.04 14.3 0.0 1.8 2 0 0 2 2 1 0 RNA helicase RsgA_GTPase PF03193.16 ORY32751.1 - 0.015 15.2 0.1 0.027 14.4 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 ORY32751.1 - 0.018 15.5 0.3 0.038 14.5 0.3 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY32751.1 - 0.019 14.7 0.1 0.065 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 ORY32751.1 - 0.03 13.8 0.1 0.16 11.4 0.1 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY32751.1 - 0.047 14.1 0.0 0.08 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ORY32751.1 - 0.057 13.7 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ORY32751.1 - 0.081 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 ORY32751.1 - 0.093 12.6 0.2 0.16 11.9 0.2 1.3 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 ORY32751.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ORY32751.1 - 0.11 12.3 0.3 0.3 10.9 0.2 1.7 1 1 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 ORY32751.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_33 PF13671.6 ORY32751.1 - 0.19 11.9 0.0 0.35 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Lectin_leg-like PF03388.13 ORY32752.1 - 2.5e-58 197.2 0.1 3.4e-58 196.7 0.1 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 ORY32752.1 - 4.4e-05 23.6 3.5 7.1e-05 22.9 3.5 1.3 1 0 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 ORY32752.1 - 0.012 15.1 0.2 0.19 11.3 0.2 2.1 1 1 0 1 1 1 0 Legume lectin domain BIR PF00653.21 ORY32753.1 - 2.6e-14 53.6 0.1 4.8e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain Imm52 PF15579.6 ORY32753.1 - 0.09 12.6 0.4 0.32 10.9 0.4 1.9 1 0 0 1 1 1 0 Immunity protein 52 MFS_1 PF07690.16 ORY32754.1 - 2.2e-19 69.6 44.5 4.2e-16 58.8 19.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Flavi_NS4A PF01350.17 ORY32754.1 - 4.3e-06 26.7 5.7 0.00042 20.3 0.2 2.8 2 0 0 2 2 2 2 Flavivirus non-structural protein NS4A Glyco_hydro_20 PF00728.22 ORY32755.1 - 4.4e-80 269.7 0.0 5e-80 269.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 ORY32755.1 - 0.15 12.9 0.1 0.25 12.1 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 Lactamase_B_2 PF12706.7 ORY32756.1 - 6.4e-20 71.5 0.1 8.4e-20 71.1 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY32756.1 - 2.8e-07 30.8 0.6 5.1e-07 29.9 0.6 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 ORY32756.1 - 0.0089 15.5 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Ezh2_MCSS PF18600.1 ORY32756.1 - 0.039 13.6 0.4 0.1 12.2 0.4 1.7 1 0 0 1 1 1 0 MCSS domain Elf1 PF05129.13 ORY32757.1 - 1.6 8.8 6.1 2.6 8.2 1.7 2.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like SET PF00856.28 ORY32759.1 - 7.4e-10 39.5 0.0 5.7e-09 36.6 0.0 2.2 2 1 0 2 2 2 1 SET domain OPT PF03169.15 ORY32760.1 - 4.6e-119 398.8 47.7 5.4e-119 398.6 47.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2109 PF09882.9 ORY32760.1 - 1.3 9.0 4.7 0.73 9.9 0.5 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) ABC_membrane PF00664.23 ORY32761.1 - 3.6e-118 394.2 16.6 2.1e-60 204.7 4.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY32761.1 - 6.6e-68 227.5 1.8 1.3e-34 119.7 0.0 2.7 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 ORY32761.1 - 8.1e-16 58.1 7.8 1.4e-06 27.9 0.0 4.2 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 ORY32761.1 - 5.7e-09 35.3 0.8 0.00028 19.8 0.3 2.6 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 ORY32761.1 - 2.6e-07 31.2 1.4 0.018 15.4 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 ORY32761.1 - 6.6e-07 29.7 1.9 0.076 13.3 0.1 3.9 2 2 0 2 2 2 2 AAA domain AAA PF00004.29 ORY32761.1 - 1.2e-06 29.0 2.7 0.063 13.7 0.1 4.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 ORY32761.1 - 1.7e-06 28.1 0.0 0.073 13.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 ORY32761.1 - 1.5e-05 24.6 0.7 0.014 15.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 ORY32761.1 - 6.7e-05 22.7 0.7 0.19 11.4 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.6 ORY32761.1 - 0.00023 21.0 0.0 0.071 12.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 ORY32761.1 - 0.00023 21.3 3.8 1 9.6 0.5 4.1 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 ORY32761.1 - 0.00036 20.5 0.4 0.32 10.9 0.0 3.0 4 0 0 4 4 2 1 Rad17 P-loop domain AAA_7 PF12775.7 ORY32761.1 - 0.0011 18.6 0.0 0.35 10.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 ORY32761.1 - 0.0027 17.0 1.4 1.9 7.7 0.0 3.4 3 1 1 4 4 4 1 Zeta toxin AAA_5 PF07728.14 ORY32761.1 - 0.0035 17.3 0.5 3.6 7.6 0.0 3.3 4 0 0 4 4 2 1 AAA domain (dynein-related subfamily) G-alpha PF00503.20 ORY32761.1 - 0.0049 16.1 0.0 0.3 10.2 0.0 2.4 2 1 0 2 2 2 1 G-protein alpha subunit Cytidylate_kin PF02224.18 ORY32761.1 - 0.0068 16.2 1.0 1.7 8.4 0.0 3.2 3 0 0 3 3 3 1 Cytidylate kinase AAA_18 PF13238.6 ORY32761.1 - 0.0077 16.8 0.1 6.1 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ORY32761.1 - 0.0085 16.3 0.1 1.1 9.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ORY32761.1 - 0.0094 16.3 0.1 9.1 6.7 0.0 2.9 2 1 0 2 2 2 0 RNA helicase DUF815 PF05673.13 ORY32761.1 - 0.012 14.8 0.0 0.48 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 ORY32761.1 - 0.019 14.7 0.0 9 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 ORY32761.1 - 0.033 14.0 0.2 2.9 7.6 0.0 3.4 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_17 PF13207.6 ORY32761.1 - 0.043 14.2 1.0 20 5.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 ORY32761.1 - 0.053 13.1 1.0 27 4.3 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.6 ORY32761.1 - 0.055 13.7 0.1 14 5.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 ORY32761.1 - 0.064 13.2 0.2 16 5.4 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase ATP_bind_1 PF03029.17 ORY32761.1 - 0.068 12.9 0.5 3.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein IstB_IS21 PF01695.17 ORY32761.1 - 0.11 12.2 1.5 20 4.9 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_23 PF13476.6 ORY32761.1 - 0.17 12.4 9.4 0.66 10.4 0.1 3.5 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.7 ORY32761.1 - 0.28 10.1 3.7 3.9 6.3 0.1 2.9 3 0 0 3 3 3 0 AAA-like domain DUF2207 PF09972.9 ORY32761.1 - 1.9 7.1 16.0 0.93 8.2 2.9 3.9 4 1 0 4 4 4 0 Predicted membrane protein (DUF2207) Glyco_hydro_18 PF00704.28 ORY32764.1 - 2.5e-76 257.4 3.4 2.5e-76 257.4 3.4 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 DJ-1_PfpI PF01965.24 ORY32765.1 - 2.3e-22 79.6 0.1 2.9e-22 79.2 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Atu4866 PF11512.8 ORY32765.1 - 0.03 14.7 0.0 0.061 13.7 0.0 1.5 1 0 0 1 1 1 0 Agrobacterium tumefaciens protein Atu4866 Sel1 PF08238.12 ORY32766.1 - 5.6e-32 109.5 29.5 4.3e-05 24.0 0.1 11.7 13 0 0 13 13 13 7 Sel1 repeat TipAS PF07739.13 ORY32766.1 - 0.038 14.6 0.2 0.4 11.2 0.0 2.6 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain TPR_6 PF13174.6 ORY32766.1 - 0.089 13.5 13.6 30 5.5 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat Ank_2 PF12796.7 ORY32767.1 - 1.1e-09 38.8 12.5 0.0037 17.8 0.1 6.4 5 3 3 8 8 8 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY32767.1 - 0.00035 20.8 6.3 0.37 11.2 0.0 6.8 6 1 1 7 7 7 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY32767.1 - 0.0016 18.8 6.2 6.2e+02 1.6 0.0 9.8 11 0 0 11 11 11 0 Ankyrin repeat Ank_4 PF13637.6 ORY32767.1 - 0.0042 17.6 4.0 1.8 9.2 0.0 5.8 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY32767.1 - 0.0043 17.4 0.9 0.24 11.9 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat DUF3447 PF11929.8 ORY32767.1 - 0.058 13.4 1.4 0.52 10.3 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3447) Acid_PPase PF12689.7 ORY32767.1 - 0.15 11.9 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Acid Phosphatase F-box-like PF12937.7 ORY32767.1 - 0.16 11.9 1.2 1 9.3 0.2 2.5 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 ORY32767.1 - 0.26 11.2 2.3 2 8.4 0.3 3.0 2 0 0 2 2 2 0 F-box domain Ank_5 PF13857.6 ORY32768.1 - 1.3e-05 25.4 3.4 0.29 11.5 0.0 4.7 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY32768.1 - 0.00064 20.3 2.3 0.62 10.7 0.1 3.6 2 2 2 4 4 4 2 Ankyrin repeats (3 copies) F-box-like PF12937.7 ORY32768.1 - 0.03 14.2 0.4 0.092 12.7 0.4 1.9 1 0 0 1 1 1 0 F-box-like Ank_3 PF13606.6 ORY32768.1 - 0.1 13.2 2.3 4.5e+02 2.0 0.1 5.5 5 1 1 6 6 6 0 Ankyrin repeat Ank_2 PF12796.7 ORY32769.1 - 0.00049 20.6 0.5 0.29 11.8 0.2 2.9 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY32769.1 - 0.04 14.5 1.2 2.5 8.8 0.0 3.5 3 1 0 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY32769.1 - 0.15 12.7 6.0 28 5.7 0.2 5.4 6 1 0 6 6 6 0 Ankyrin repeat Ras PF00071.22 ORY32770.1 - 7.6e-37 126.4 0.0 9.2e-37 126.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY32770.1 - 6e-12 45.8 0.0 9.4e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORY32770.1 - 2.4e-05 24.4 0.1 5.1e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY32770.1 - 5.4e-05 22.8 0.0 0.0052 16.3 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IstB_IS21 PF01695.17 ORY32770.1 - 0.02 14.6 0.0 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein FeoB_N PF02421.18 ORY32770.1 - 0.11 12.1 0.1 5.4 6.5 0.0 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_33 PF13671.6 ORY32770.1 - 0.17 12.1 0.0 0.36 11.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain THEG4 PF15834.5 ORY32771.1 - 0.097 12.7 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Testis highly expressed protein 4 ABC_membrane PF00664.23 ORY32772.1 - 1.1e-120 402.4 13.0 7.4e-62 209.5 1.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY32772.1 - 6.7e-68 227.5 3.3 2.2e-34 118.9 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 ORY32772.1 - 9.5e-17 61.2 6.9 2.2e-07 30.5 0.0 4.4 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY32772.1 - 4.1e-07 30.5 0.4 0.071 13.5 0.2 3.1 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORY32772.1 - 2.9e-06 27.3 0.0 0.049 13.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 ORY32772.1 - 7.2e-06 26.3 1.7 0.047 14.0 0.2 3.6 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 ORY32772.1 - 1.2e-05 25.5 3.6 0.052 13.8 0.3 4.2 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 ORY32772.1 - 1.3e-05 24.3 0.8 0.046 12.5 0.0 2.3 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 ORY32772.1 - 0.00011 21.8 1.0 0.1 12.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 ORY32772.1 - 0.00013 21.8 0.2 0.51 10.0 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA PF00004.29 ORY32772.1 - 0.00018 22.0 4.5 0.25 11.8 0.1 4.1 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ORY32772.1 - 0.0005 19.6 0.0 0.56 9.7 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 ORY32772.1 - 0.0013 18.1 0.4 6.7 5.9 0.0 3.4 3 0 0 3 3 3 0 Zeta toxin AAA_15 PF13175.6 ORY32772.1 - 0.0018 18.0 0.1 0.2 11.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Glyoxalase_3 PF13468.6 ORY32772.1 - 0.002 18.3 0.0 0.11 12.6 0.0 2.5 2 0 0 2 2 2 1 Glyoxalase-like domain Rad17 PF03215.15 ORY32772.1 - 0.0035 17.3 0.0 0.27 11.1 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain G-alpha PF00503.20 ORY32772.1 - 0.0098 15.1 0.1 3 6.9 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit AAA_21 PF13304.6 ORY32772.1 - 0.012 15.5 0.4 3.6 7.3 0.0 3.9 6 0 0 6 6 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 ORY32772.1 - 0.012 15.6 0.4 8.9 6.3 0.0 3.3 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AIG1 PF04548.16 ORY32772.1 - 0.034 13.5 0.1 2.5 7.4 0.0 2.6 2 0 0 2 2 2 0 AIG1 family DUF815 PF05673.13 ORY32772.1 - 0.039 13.1 0.0 4.7 6.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 ORY32772.1 - 0.041 14.3 0.1 16 5.9 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 ORY32772.1 - 0.053 14.0 6.2 1.9 9.0 0.1 3.2 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.7 ORY32772.1 - 0.055 12.4 0.1 2.7 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain MoaE PF02391.17 ORY32772.1 - 0.055 13.7 0.9 13 6.1 0.1 2.7 2 0 0 2 2 2 0 MoaE protein AAA_24 PF13479.6 ORY32772.1 - 0.06 13.1 0.1 9.4 5.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ORY32772.1 - 0.076 12.6 0.3 19 4.8 0.0 3.5 4 0 0 4 4 3 0 AAA domain KorB PF08535.10 ORY32772.1 - 0.098 12.7 0.1 41 4.3 0.0 3.5 3 0 0 3 3 3 0 KorB domain PRK PF00485.18 ORY32772.1 - 0.11 12.2 0.2 7.9 6.2 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 ORY32772.1 - 0.15 12.2 0.4 9.9 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ORY32772.1 - 0.34 10.6 2.3 36 4.0 0.0 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein Hydrolase PF00702.26 ORY32773.1 - 5.9e-09 36.5 0.6 2.1e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY32773.1 - 0.0005 20.2 1.4 0.00095 19.3 0.1 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY32773.1 - 0.0011 18.9 0.0 0.0032 17.5 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like LCD1 PF09798.9 ORY32773.1 - 0.33 9.4 7.0 0.36 9.3 7.0 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein Mce4_CUP1 PF11887.8 ORY32774.1 - 0.0094 15.4 2.6 0.02 14.4 0.8 2.3 2 0 0 2 2 2 1 Cholesterol uptake porter CUP1 of Mce4, putative TFA2_Winged_2 PF18121.1 ORY32774.1 - 0.049 13.3 0.8 0.48 10.1 0.1 2.8 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 MRP-S28 PF10213.9 ORY32774.1 - 1.3 9.4 8.2 18 5.8 0.1 2.7 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit protein SNF2_N PF00176.23 ORY32776.1 - 3.6e-67 226.5 0.0 6e-67 225.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY32776.1 - 6.2e-16 58.7 0.0 1.7e-15 57.3 0.0 1.8 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 ORY32776.1 - 2.3e-08 33.9 1.8 2.3e-08 33.9 1.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger ResIII PF04851.15 ORY32776.1 - 3.9e-08 33.5 0.0 7.4e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 ORY32776.1 - 5.4e-08 32.5 3.4 5.4e-08 32.5 3.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY32776.1 - 9.7e-08 32.0 4.2 2.8e-07 30.6 4.2 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 ORY32776.1 - 7.9e-07 28.9 7.5 1.7e-06 27.8 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY32776.1 - 2e-06 28.0 7.6 5.1e-06 26.7 7.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 ORY32776.1 - 8.9e-06 25.6 6.1 1.9e-05 24.5 6.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY32776.1 - 4.2e-05 23.3 6.9 0.00013 21.7 6.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY32776.1 - 0.00037 20.3 6.3 0.0019 18.0 6.3 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 TEBP_beta PF07404.11 ORY32776.1 - 0.0025 17.2 0.5 0.0042 16.5 0.5 1.3 1 0 0 1 1 1 1 Telomere-binding protein beta subunit (TEBP beta) SWI2_SNF2 PF18766.1 ORY32776.1 - 0.006 16.3 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Zn_Tnp_IS91 PF14319.6 ORY32776.1 - 0.079 13.0 0.3 0.22 11.6 0.3 1.7 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-Nse PF11789.8 ORY32776.1 - 0.11 12.3 2.4 0.36 10.7 2.4 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C2H2_9 PF16293.5 ORY32776.1 - 0.12 12.2 0.2 0.33 10.8 0.2 1.7 1 0 0 1 1 1 0 C2H2 type zinc-finger (1 copy) zf-rbx1 PF12678.7 ORY32776.1 - 0.16 12.3 4.7 0.51 10.7 4.7 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 ORY32776.1 - 0.35 10.8 1.6 0.98 9.3 1.6 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1272 PF06906.11 ORY32776.1 - 2.4 8.3 5.1 2.8 8.1 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DUF1413 PF07205.11 ORY32777.1 - 0.12 12.4 0.0 0.49 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1413) Yippee-Mis18 PF03226.14 ORY32778.1 - 7.2 6.9 9.6 7.2 6.9 1.1 3.0 1 1 2 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RibD_C PF01872.17 ORY32779.1 - 1.4e-21 77.3 0.0 1.6e-21 77.1 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain FHA PF00498.26 ORY32980.1 - 3.7e-19 68.8 0.1 6.3e-19 68.1 0.1 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 ORY32980.1 - 7.8e-07 29.3 0.0 6.2e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PAS_8 PF13188.7 ORY32981.1 - 0.00051 20.0 0.0 0.0055 16.7 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_9 PF13426.7 ORY32981.1 - 0.0016 18.7 0.0 0.025 14.8 0.0 2.6 2 1 0 2 2 2 1 PAS domain PAS PF00989.25 ORY32981.1 - 0.014 15.4 0.0 0.07 13.1 0.0 2.2 2 0 0 2 2 2 0 PAS fold PAS_4 PF08448.10 ORY32981.1 - 0.021 15.1 0.0 0.5 10.6 0.0 2.5 2 0 0 2 2 2 0 PAS fold Macoilin PF09726.9 ORY32981.1 - 0.093 11.3 0.9 0.15 10.6 0.9 1.2 1 0 0 1 1 1 0 Macoilin family PRP21_like_P PF12230.8 ORY32985.1 - 1.3e-39 136.4 0.0 1.3e-39 136.4 0.0 2.7 3 0 0 3 3 3 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 ORY32985.1 - 1e-37 127.9 4.3 2.4e-19 69.1 0.2 2.4 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 ORY32985.1 - 0.00025 20.6 0.2 0.00056 19.4 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger ubiquitin PF00240.23 ORY32985.1 - 0.042 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family zinc_ribbon_16 PF17034.5 ORY32985.1 - 0.16 12.1 0.4 2 8.6 0.1 2.2 2 0 0 2 2 2 0 Zinc-ribbon like family CTU2 PF10288.9 ORY32985.1 - 1.2 9.4 5.9 11 6.3 1.0 2.7 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 PC-Esterase PF13839.6 ORY32987.1 - 8.6e-06 25.7 0.5 0.84 9.3 0.0 3.3 3 1 0 3 3 3 3 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p LMBR1 PF04791.16 ORY32989.1 - 3.4e-116 389.2 20.5 4e-116 388.9 20.5 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF2959 PF11172.8 ORY32990.1 - 0.003 17.7 1.3 0.73 9.9 0.1 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF2959) MitMem_reg PF13012.6 ORY32990.1 - 0.55 10.7 2.9 1.6 9.2 0.2 3.1 2 2 1 3 3 3 0 Maintenance of mitochondrial structure and function DCB PF16213.5 ORY32990.1 - 5.7 6.6 10.9 0.21 11.3 2.2 3.0 2 1 2 4 4 4 0 Dimerisation and cyclophilin-binding domain of Mon2 Sipho_Gp157 PF05565.11 ORY32990.1 - 9.4 6.2 10.2 0.83 9.6 0.4 3.6 4 0 0 4 4 4 0 Siphovirus Gp157 dCMP_cyt_deam_1 PF00383.23 ORY32991.1 - 4.4e-10 39.4 0.0 7.5e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY32991.1 - 9.2e-05 22.2 0.3 0.0052 16.5 0.0 2.3 2 0 0 2 2 2 2 MafB19-like deaminase DUF2109 PF09882.9 ORY32992.1 - 2.9 8.0 5.5 1.8 8.6 0.5 2.8 2 1 1 3 3 3 0 Predicted membrane protein (DUF2109) ubiquitin PF00240.23 ORY32993.1 - 1.3e-18 66.5 0.3 2.7e-18 65.5 0.1 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 ORY32993.1 - 0.0024 17.7 0.0 0.005 16.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 ORY32993.1 - 0.079 12.9 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ribosomal_L15e PF00827.17 ORY32993.1 - 0.24 11.1 1.2 0.35 10.6 1.2 1.2 1 0 0 1 1 1 0 Ribosomal L15 NAM-associated PF14303.6 ORY32993.1 - 0.52 11.0 4.0 0.9 10.2 4.0 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain HXXEE PF13787.6 ORY32995.1 - 0.31 11.8 0.0 0.31 11.8 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function with HXXEE motif Pkinase PF00069.25 ORY32997.1 - 1.8e-07 30.8 0.1 1.4e-05 24.6 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain ILVD_EDD PF00920.21 ORY32998.1 - 7e-127 424.2 0.6 1.3e-125 420.0 0.6 2.7 1 1 0 1 1 1 1 Dehydratase family Ribosomal_S9 PF00380.19 ORY32999.1 - 1e-19 71.2 0.1 1.2e-19 71.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L32e PF01655.18 ORY33000.1 - 8.7e-52 174.1 0.2 1.1e-51 173.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 DCP1 PF06058.13 ORY33001.1 - 6.5e-38 129.3 0.3 7.1e-38 129.1 0.3 1.0 1 0 0 1 1 1 1 Dcp1-like decapping family MAGE PF01454.19 ORY33002.1 - 3.7e-35 121.6 3.8 4.1e-34 118.2 3.8 2.1 1 1 0 1 1 1 1 MAGE family Vps5 PF09325.10 ORY33003.1 - 5.9e-06 26.0 2.7 7.2e-06 25.7 2.6 1.2 1 1 0 1 1 1 1 Vps5 C terminal like DUF3759 PF12585.8 ORY33004.1 - 5.9e-08 32.6 0.0 6.4e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3759 PF12585.8 ORY33005.1 - 1.8e-18 66.3 4.2 1.8e-18 66.3 4.2 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3759) Serine_protease PF18405.1 ORY33005.1 - 0.15 11.2 0.0 0.18 10.9 0.0 1.1 1 0 0 1 1 1 0 Gammaproteobacterial serine protease PH PF00169.29 ORY33183.1 - 0.00044 20.7 0.0 0.00093 19.7 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 ORY33183.1 - 0.045 14.0 0.9 1.3 9.3 0.9 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain PH PF00169.29 ORY33184.1 - 1.5e-05 25.4 0.0 2.8e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 ORY33184.1 - 0.076 13.4 0.0 0.51 10.8 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain PH_8 PF15409.6 ORY33184.1 - 0.18 12.1 0.1 3.5 8.0 0.1 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain DUF2718 PF10918.8 ORY33185.1 - 0.62 10.6 2.7 0.31 11.6 1.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2718) PH PF00169.29 ORY33187.1 - 1.5e-08 35.1 0.0 3.2e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 ORY33187.1 - 0.23 11.9 0.7 1.2 9.6 0.0 2.6 3 1 0 3 3 3 0 Pleckstrin homology domain PH PF00169.29 ORY33188.1 - 0.00017 22.1 0.0 0.0004 20.9 0.0 1.6 1 0 0 1 1 1 1 PH domain PH PF00169.29 ORY33189.1 - 2.5e-09 37.6 0.0 4.3e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 ORY33189.1 - 0.019 15.4 0.1 0.41 11.1 0.1 2.4 1 1 0 1 1 1 0 Pleckstrin homology domain PH PF00169.29 ORY33190.1 - 0.032 14.7 0.0 0.1 13.1 0.0 1.8 1 1 0 1 1 1 0 PH domain PH_15 PF17339.2 ORY33191.1 - 9.1e-05 22.3 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 PH domain PH PF00169.29 ORY33191.1 - 0.0022 18.5 0.0 0.0034 17.8 0.0 1.3 1 0 0 1 1 1 1 PH domain ZapB PF06005.12 ORY33191.1 - 0.24 11.9 6.2 0.36 11.3 3.9 2.2 2 0 0 2 2 2 0 Cell division protein ZapB PH PF00169.29 ORY33192.1 - 2.4e-08 34.4 0.0 5.2e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 PH domain DisA-linker PF10635.9 ORY33192.1 - 0.0095 15.7 0.1 0.0095 15.7 0.1 1.7 2 0 0 2 2 2 1 DisA bacterial checkpoint controller linker region PH_17 PF18012.1 ORY33192.1 - 0.055 13.2 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 PH domain VID27_PH PF17747.1 ORY33192.1 - 0.097 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 VID27 PH-like domain SurA_N_2 PF13623.6 ORY33192.1 - 0.91 9.4 8.0 1.7 8.5 8.0 1.3 1 0 0 1 1 1 0 SurA N-terminal domain Sporozoite_P67 PF05642.11 ORY33192.1 - 1.6 6.7 7.4 2.6 6.0 7.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF1501 PF07394.12 ORY33192.1 - 2.4 7.1 5.6 3.6 6.5 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) PH PF00169.29 ORY33193.1 - 0.011 16.2 0.1 0.029 14.9 0.1 1.6 1 1 0 1 1 1 0 PH domain PH PF00169.29 ORY33194.1 - 4.9e-06 27.0 0.0 1.4e-05 25.5 0.0 1.8 2 0 0 2 2 2 1 PH domain TFIIA PF03153.13 ORY33194.1 - 0.013 15.5 8.0 0.016 15.3 8.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1682 PF07946.14 ORY33194.1 - 2.9 7.0 15.2 4.7 6.3 15.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Pannexin_like PF12534.8 ORY33194.1 - 5.1 6.1 8.9 7.7 5.5 8.9 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 PH PF00169.29 ORY33195.1 - 0.02 15.4 0.1 0.04 14.4 0.1 1.4 1 0 0 1 1 1 0 PH domain Cellulase PF00150.18 ORY33196.1 - 0.00011 21.7 0.0 0.00025 20.6 0.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4131 PF13567.6 ORY33196.1 - 0.34 10.6 3.6 0.44 10.2 2.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) BK_channel_a PF03493.18 ORY33197.1 - 7.4e-16 58.1 0.0 1.7e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 ORY33197.1 - 3.7e-14 52.5 5.8 8.4e-14 51.3 5.8 1.6 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 ORY33197.1 - 0.00019 20.8 0.8 0.00031 20.1 0.8 1.3 1 0 0 1 1 1 1 Ion transport protein TrkA_N PF02254.18 ORY33197.1 - 0.00046 20.4 0.0 0.32 11.3 0.0 2.6 2 0 0 2 2 2 2 TrkA-N domain Castor_Poll_mid PF06241.12 ORY33197.1 - 0.065 13.2 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 Castor and Pollux, part of voltage-gated ion channel Ion_trans_2 PF07885.16 ORY33199.1 - 9.6e-13 47.9 9.4 1.6e-12 47.2 9.4 1.3 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 ORY33199.1 - 0.00016 21.0 1.3 0.00023 20.5 1.3 1.2 1 0 0 1 1 1 1 Ion transport protein APO_RNA-bind PF05634.11 ORY33199.1 - 0.17 11.2 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 APO RNA-binding TatC PF00902.18 ORY33200.1 - 1.5 8.6 11.9 0.071 12.9 6.4 1.5 2 0 0 2 2 2 0 Sec-independent protein translocase protein (TatC) DUF1673 PF07895.11 ORY33200.1 - 2.7 7.6 12.0 1.2 8.8 4.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) zf-C2H2_10 PF16588.5 ORY33202.1 - 0.55 10.0 9.0 1.2 9.0 9.0 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger BK_channel_a PF03493.18 ORY33203.1 - 1.7e-18 66.6 0.1 1.9e-18 66.4 0.1 1.1 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 ORY33204.1 - 7.2e-11 41.9 7.1 1.1e-10 41.3 7.1 1.4 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 ORY33204.1 - 0.00011 21.6 0.6 0.00011 21.6 0.6 1.6 2 0 0 2 2 2 1 Ion transport protein PAN_1 PF00024.26 ORY33205.1 - 2.3e-06 27.5 8.5 3.1e-06 27.1 0.0 3.7 3 0 0 3 3 3 1 PAN domain PAN_4 PF14295.6 ORY33205.1 - 0.012 15.5 0.1 0.012 15.5 0.1 3.0 3 0 0 3 3 3 0 PAN domain PAN_3 PF08277.12 ORY33205.1 - 1.9 8.4 12.8 0.42 10.4 0.2 3.9 3 0 0 3 3 3 0 PAN-like domain DSS1_SEM1 PF05160.13 ORY33207.1 - 2.3e-15 56.4 10.0 2.5e-15 56.3 10.0 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family Peptidase_M43 PF05572.13 ORY33208.1 - 2.1e-12 47.2 0.2 3.8e-12 46.4 0.2 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 ORY33208.1 - 0.00048 20.6 0.2 0.00072 20.1 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 ORY33208.1 - 0.0006 20.0 0.6 0.00078 19.6 0.6 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.24 ORY33208.1 - 0.02 14.7 1.0 0.038 13.8 1.0 1.5 1 1 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.9 ORY33208.1 - 0.024 13.6 0.6 0.033 13.1 0.2 1.5 2 0 0 2 2 2 0 Peptidase M66 Reprolysin_4 PF13583.6 ORY33208.1 - 0.026 14.2 0.1 0.031 13.9 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.16 ORY33208.1 - 0.032 14.3 0.1 0.059 13.5 0.1 1.6 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Reprolysin_2 PF13574.6 ORY33208.1 - 0.052 13.4 0.5 0.088 12.7 0.4 1.3 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 ORY33208.1 - 0.18 11.0 0.0 0.25 10.5 0.0 1.1 1 0 0 1 1 1 0 Met-zincin Lyase_1 PF00206.20 ORY33209.1 - 1.1e-97 327.2 0.0 1.4e-97 326.8 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 ORY33209.1 - 2.1e-20 73.2 0.2 4.8e-20 72.1 0.2 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF309 PF03745.14 ORY33209.1 - 0.077 12.7 0.1 0.2 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF309) Umbravirus_LDM PF04817.12 ORY33209.1 - 0.13 11.6 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family Phosphoesterase PF04185.14 ORY33211.1 - 3.4e-28 98.9 0.2 7.5e-27 94.4 0.2 2.0 1 1 0 1 1 1 1 Phosphoesterase family Phosphoesterase PF04185.14 ORY33213.1 - 3.3e-30 105.5 0.2 1.6e-28 99.9 0.2 2.0 1 1 0 1 1 1 1 Phosphoesterase family Phosphoesterase PF04185.14 ORY33214.1 - 2.6e-26 92.7 2.1 4.6e-25 88.6 2.1 2.0 1 1 0 1 1 1 1 Phosphoesterase family CLTH PF10607.9 ORY33215.1 - 1.7e-32 112.3 3.1 1.7e-32 112.3 3.1 1.9 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain U-box PF04564.15 ORY33215.1 - 4e-05 23.7 0.0 0.00015 21.9 0.0 1.9 1 0 0 1 1 1 1 U-box domain BIR PF00653.21 ORY33215.1 - 0.13 12.9 0.9 0.35 11.5 0.1 2.2 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain YlqD PF11068.8 ORY33215.1 - 0.24 11.8 3.4 0.55 10.6 3.4 1.6 1 0 0 1 1 1 0 YlqD protein SOG2 PF10428.9 ORY33216.1 - 1.1 8.3 18.2 1.5 8.0 18.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Utp14 PF04615.13 ORY33217.1 - 2.3e-129 433.3 43.6 2.3e-129 433.3 43.6 3.8 1 1 1 2 2 2 1 Utp14 protein DUF563 PF04577.14 ORY33217.1 - 2.7e-11 44.0 0.0 4.7e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Lipoprotein_11 PF03260.13 ORY33218.1 - 0.26 10.6 0.0 0.37 10.1 0.0 1.1 1 0 0 1 1 1 0 Lepidopteran low molecular weight (30 kD) lipoprotein Memo PF01875.17 ORY33219.1 - 4.3e-55 186.8 0.0 1.6e-53 181.6 0.0 2.0 1 1 0 1 1 1 1 Memo-like protein Rad51 PF08423.11 ORY33220.1 - 2.4e-17 63.0 0.0 2.9e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 ORY33220.1 - 3e-06 26.7 0.4 4.4e-06 26.2 0.4 1.2 1 0 0 1 1 1 1 KaiC RecA PF00154.21 ORY33220.1 - 0.00033 20.2 0.3 0.00053 19.5 0.3 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 ORY33220.1 - 0.0026 17.4 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY33220.1 - 0.018 15.2 0.1 0.033 14.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain Rad51 PF08423.11 ORY33221.1 - 1.1e-06 28.1 0.0 1.2e-06 27.9 0.0 1.0 1 0 0 1 1 1 1 Rad51 Ank_2 PF12796.7 ORY33222.1 - 2.5e-19 69.7 0.5 4e-06 27.3 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY33222.1 - 4.3e-11 42.8 3.5 0.085 13.2 0.0 5.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY33222.1 - 5e-08 32.6 2.6 0.85 10.4 0.0 5.9 6 0 0 6 6 6 2 Ankyrin repeat Ank_4 PF13637.6 ORY33222.1 - 1.7e-06 28.4 2.3 0.026 15.1 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY33222.1 - 0.017 15.6 5.7 23 5.6 0.1 5.1 3 2 1 4 4 4 0 Ankyrin repeat F-box-like PF12937.7 ORY33222.1 - 0.092 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 F-box-like Ank_2 PF12796.7 ORY33223.1 - 7.2e-11 42.5 1.3 3.3e-07 30.8 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY33223.1 - 0.0001 22.5 3.3 0.002 18.4 0.1 3.6 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY33223.1 - 0.0021 18.4 1.3 41 5.2 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 ORY33223.1 - 0.008 16.7 0.1 3.5 8.3 0.0 2.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY33224.1 - 2.8e-15 56.7 0.0 0.00046 20.7 0.0 5.4 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY33224.1 - 8e-09 35.9 2.9 0.0069 17.0 0.0 4.9 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY33224.1 - 2.4e-08 33.6 5.2 1.1 10.0 0.0 7.8 7 1 2 9 9 9 2 Ankyrin repeat Ank_5 PF13857.6 ORY33224.1 - 2e-06 28.0 2.1 4 7.9 0.0 6.2 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY33224.1 - 0.014 15.8 0.5 25 5.6 0.0 4.6 6 0 0 6 6 6 0 Ankyrin repeat Peptidase_M43 PF05572.13 ORY33225.1 - 1e-12 48.2 0.2 1.7e-12 47.5 0.2 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 ORY33225.1 - 0.00029 21.0 0.1 0.00036 20.7 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 ORY33225.1 - 0.00058 20.4 0.0 0.00079 19.9 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 ORY33225.1 - 0.0024 17.5 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 ORY33225.1 - 0.0042 16.9 0.1 0.0066 16.3 0.1 1.5 1 1 0 1 1 1 1 Matrixin DUF4953 PF16313.5 ORY33225.1 - 0.036 13.3 0.7 0.064 12.5 0.3 1.5 2 0 0 2 2 2 0 Met-zincin Peptidase_M66 PF10462.9 ORY33225.1 - 0.11 11.5 0.7 0.18 10.7 0.7 1.3 1 0 0 1 1 1 0 Peptidase M66 VirD1 PF07328.11 ORY33228.1 - 0.037 14.0 0.0 0.044 13.8 0.0 1.1 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 LRR_4 PF12799.7 ORY33229.1 - 4.9e-05 23.6 4.2 0.0025 18.2 0.5 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY33229.1 - 0.018 15.5 3.6 17 6.5 0.0 4.3 3 2 1 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 ORY33229.1 - 0.14 12.3 7.0 9.5 6.6 0.1 3.7 4 0 0 4 4 4 0 Leucine Rich repeat LRR_8 PF13855.6 ORY33229.1 - 0.23 11.2 4.2 1.1 9.1 2.8 2.5 1 1 1 2 2 2 0 Leucine rich repeat Pax2_C PF12403.8 ORY33229.1 - 0.25 11.5 1.0 1.5 8.9 0.1 2.4 2 1 0 2 2 2 0 Paired-box protein 2 C terminal zf-C2HC_2 PF13913.6 ORY33234.1 - 4.4e-09 36.0 1.4 7.9e-09 35.2 1.4 1.4 1 0 0 1 1 1 1 zinc-finger of a C2HC-type Paf1 PF03985.13 ORY33234.1 - 0.44 9.5 11.8 0.73 8.8 11.8 1.3 1 0 0 1 1 1 0 Paf1 FYDLN_acid PF09538.10 ORY33234.1 - 1.4 9.7 15.0 0.88 10.3 7.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) CAF1A PF12253.8 ORY33234.1 - 1.8 8.8 10.7 4.2 7.6 10.7 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A CDC45 PF02724.14 ORY33234.1 - 3.3 5.9 8.5 3.5 5.8 8.5 1.2 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.10 ORY33234.1 - 3.5 8.1 11.2 7 7.1 11.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain LAP1C PF05609.12 ORY33234.1 - 4.7 6.2 11.5 5.7 5.9 11.5 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RNA_pol_3_Rpc31 PF11705.8 ORY33234.1 - 6.1 7.0 17.4 0.3 11.3 10.1 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 ORY33234.1 - 9.1 4.2 13.8 12 3.8 13.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Myb_DNA-binding PF00249.31 ORY33235.1 - 1.2e-22 79.8 1.8 7.2e-07 29.3 0.1 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 ORY33235.1 - 1.9e-09 37.3 0.7 0.00042 20.2 0.1 3.7 3 0 0 3 3 3 3 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 ORY33235.1 - 2.7e-05 24.3 0.3 0.16 12.2 0.1 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Importin_rep PF18773.1 ORY33235.1 - 0.1 12.3 1.0 5.8 6.7 0.1 2.9 2 0 0 2 2 2 0 Importin 13 repeat Histone PF00125.24 ORY33236.1 - 2.9e-21 76.2 0.3 3.9e-21 75.8 0.3 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY33236.1 - 2.7e-06 27.6 0.1 6e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 ORY33236.1 - 0.00015 22.2 0.0 0.00026 21.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Aminotran_4 PF01063.19 ORY33237.1 - 8.8e-16 58.4 0.0 3.7e-15 56.4 0.0 1.9 1 1 0 1 1 1 1 Amino-transferase class IV DUF4097 PF13349.6 ORY33238.1 - 1.2e-06 28.1 10.7 2.1e-05 24.0 10.7 2.3 1 1 0 1 1 1 1 Putative adhesin DUF4097 PF13349.6 ORY33239.1 - 1.9e-10 40.5 15.9 4.2e-10 39.4 9.6 2.1 1 1 1 2 2 2 2 Putative adhesin zf-MYND PF01753.18 ORY33240.1 - 8.1e-09 35.4 11.8 1.6e-08 34.5 11.8 1.6 1 0 0 1 1 1 1 MYND finger Ank_2 PF12796.7 ORY33240.1 - 3.5e-05 24.3 0.1 0.00013 22.5 0.0 2.1 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY33240.1 - 0.00065 20.0 0.0 0.68 10.3 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY33240.1 - 0.0012 19.2 0.0 1.5 9.4 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat TPR_12 PF13424.6 ORY33240.1 - 0.024 14.9 0.0 0.062 13.6 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C6H2 PF15801.5 ORY33240.1 - 0.57 10.5 7.1 2.2 8.7 7.1 2.0 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DnaJ PF00226.31 ORY33241.1 - 0.082 13.0 0.2 0.82 9.8 0.3 2.4 2 1 0 2 2 2 0 DnaJ domain Bac_thur_toxin PF01338.18 ORY33241.1 - 0.093 12.2 0.2 0.13 11.7 0.2 1.3 1 1 0 1 1 1 0 Bacillus thuringiensis toxin BRCA-2_OB1 PF09103.10 ORY33242.1 - 1e-28 99.8 0.0 1.6e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 GAS2 PF02187.17 ORY33242.1 - 0.045 13.9 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain RNase_T PF00929.24 ORY33244.1 - 1.4e-33 116.8 0.0 1.6e-33 116.6 0.0 1.0 1 0 0 1 1 1 1 Exonuclease UPF0113_N PF17833.1 ORY33245.1 - 4.2e-31 107.3 0.0 6.6e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 ORY33245.1 - 9.5e-25 86.7 0.0 1.7e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 UPF0113 PUA domain DUF5418 PF17439.2 ORY33245.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5418) DUF4097 PF13349.6 ORY33246.1 - 1.1e-18 67.5 9.2 2.5e-10 40.1 0.2 2.1 1 1 1 2 2 2 2 Putative adhesin DUF3251 PF11622.8 ORY33246.1 - 0.02 14.5 0.6 1 9.0 0.0 3.3 2 1 1 4 4 4 0 Protein of unknown function (DUF3251) HLH PF00010.26 ORY33247.1 - 1.3e-08 34.6 0.1 2.2e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 ORY33248.1 - 0.0064 16.4 2.4 0.011 15.7 2.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PKcGMP_CC PF16808.5 ORY33248.1 - 0.11 12.3 1.1 1.6 8.6 1.1 2.3 1 1 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Ank_2 PF12796.7 ORY33250.1 - 3.3e-37 126.9 9.8 1.9e-06 28.4 0.0 8.7 5 1 4 9 9 9 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY33250.1 - 1.2e-15 56.0 9.0 0.97 10.2 0.0 13.5 15 1 1 16 16 16 2 Ankyrin repeat Ank_5 PF13857.6 ORY33250.1 - 6.6e-13 48.6 8.1 0.042 14.2 0.1 9.3 7 3 4 11 11 11 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY33250.1 - 5.1e-11 42.9 13.9 0.86 10.3 0.0 9.0 7 3 0 9 9 9 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY33250.1 - 0.0001 22.6 5.0 17 6.0 0.0 8.4 9 1 1 10 10 10 1 Ankyrin repeat F-box-like PF12937.7 ORY33250.1 - 0.019 14.8 0.3 0.052 13.5 0.3 1.8 1 0 0 1 1 1 0 F-box-like APC1_C PF18122.1 ORY33251.1 - 3.7e-17 62.8 0.0 8.9e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain PC_rep PF01851.22 ORY33251.1 - 1.5e-06 28.3 1.5 1.5 9.4 0.0 4.9 4 0 0 4 4 4 3 Proteasome/cyclosome repeat LRR_4 PF12799.7 ORY33252.1 - 2.7e-12 46.7 25.9 0.00011 22.5 1.6 5.6 3 1 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY33252.1 - 2.1e-11 43.4 19.7 4.5e-05 23.1 0.8 5.0 3 1 2 5 5 5 4 Leucine rich repeat HALZ PF02183.18 ORY33252.1 - 1.8e-05 24.8 0.7 6.1e-05 23.2 0.7 1.9 1 0 0 1 1 1 1 Homeobox associated leucine zipper LRR_1 PF00560.33 ORY33252.1 - 0.0069 16.8 35.1 0.7 10.7 0.1 8.8 8 2 2 10 10 10 3 Leucine Rich Repeat DivIC PF04977.15 ORY33252.1 - 0.024 14.4 0.5 0.046 13.5 0.5 1.4 1 0 0 1 1 1 0 Septum formation initiator F-box-like PF12937.7 ORY33252.1 - 0.044 13.7 0.2 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 ORY33252.1 - 0.065 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 F-box domain Med21 PF11221.8 ORY33252.1 - 0.087 13.1 1.5 0.14 12.4 1.5 1.3 1 0 0 1 1 1 0 Subunit 21 of Mediator complex LacAB_rpiB PF02502.18 ORY33253.1 - 0.056 13.4 1.0 0.18 11.8 0.1 2.0 2 0 0 2 2 2 0 Ribose/Galactose Isomerase ZF-HD_dimer PF04770.12 ORY33253.1 - 3.3 8.1 9.2 13 6.2 1.2 2.4 2 0 0 2 2 2 0 ZF-HD protein dimerisation region MOSC PF03473.17 ORY33254.1 - 5.7e-29 100.8 0.0 9.2e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 ORY33254.1 - 2.1e-27 95.4 0.0 3.8e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Arf PF00025.21 ORY33255.1 - 1.7e-69 232.7 0.1 2e-69 232.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORY33255.1 - 1.2e-11 44.4 0.0 1.6e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 ORY33255.1 - 1.4e-11 44.7 0.0 1.9e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 ORY33255.1 - 1.5e-11 44.1 0.0 1.8e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 ORY33255.1 - 1.5e-11 44.1 0.2 2.2e-06 27.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 ORY33255.1 - 1.2e-09 38.0 0.0 1.3e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 ORY33255.1 - 8.2e-08 32.3 0.0 1.3e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY33255.1 - 4.3e-06 26.4 0.0 0.00011 21.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 ORY33255.1 - 0.0038 17.7 0.1 0.013 16.0 0.1 1.8 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 ORY33255.1 - 0.016 15.5 0.0 0.022 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ORY33255.1 - 0.042 14.3 0.7 0.096 13.2 0.7 1.5 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ORY33255.1 - 0.053 13.4 0.0 10 6.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 ORY33255.1 - 0.064 13.2 0.2 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 NACHT domain zf-MYND PF01753.18 ORY33256.1 - 2.3e-07 30.8 17.5 2.3e-07 30.8 17.5 2.3 2 0 0 2 2 2 1 MYND finger PEN-2 PF10251.9 ORY33257.1 - 0.027 14.9 0.1 1.1 9.7 0.0 2.1 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase DUF3975 PF13126.6 ORY33258.1 - 2.6 8.5 7.3 6.4 7.3 0.0 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF3975) PS_Dcarbxylase PF02666.15 ORY33260.1 - 1.9e-65 220.2 0.0 2.2e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase CLTH PF10607.9 ORY33261.1 - 1.2e-38 132.3 0.7 1.7e-38 131.9 0.7 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 ORY33261.1 - 1.3e-08 34.5 0.2 4.1e-08 32.9 0.1 1.8 2 0 0 2 2 2 1 LisH AAA_31 PF13614.6 ORY33261.1 - 0.021 14.8 0.1 0.043 13.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain TPR_19 PF14559.6 ORY33261.1 - 0.14 12.7 1.6 1.1 9.9 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Sec23_trunk PF04811.15 ORY33262.1 - 6.9e-77 258.3 0.0 9.7e-77 257.8 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 ORY33262.1 - 2.5e-30 105.1 0.1 4.7e-30 104.2 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 ORY33262.1 - 5.5e-27 93.6 0.1 1e-26 92.7 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 ORY33262.1 - 4.5e-10 39.3 0.0 1.4e-09 37.7 0.0 1.9 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 ORY33262.1 - 3.7e-08 33.3 0.4 8.3e-08 32.2 0.4 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger PAS_7 PF12860.7 ORY33262.1 - 0.03 14.5 0.2 9.2 6.5 0.1 2.5 2 0 0 2 2 2 0 PAS fold Tim17 PF02466.19 ORY33263.1 - 2.8e-28 98.5 9.5 3.7e-28 98.1 9.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DEC-1_N PF04625.13 ORY33263.1 - 0.046 12.7 2.8 0.052 12.6 2.8 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Macro PF01661.21 ORY33264.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Macro domain SKG6 PF08693.10 ORY33266.1 - 4e-06 26.1 0.3 4e-06 26.1 0.3 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain RCR PF12273.8 ORY33266.1 - 0.00082 20.0 6.2 0.0017 19.0 6.2 1.4 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Mid2 PF04478.12 ORY33266.1 - 0.0026 17.6 0.2 0.0045 16.8 0.2 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TrbC PF04956.13 ORY33266.1 - 0.014 15.6 0.6 0.043 14.0 0.6 1.8 1 0 0 1 1 1 0 TrbC/VIRB2 family Podoplanin PF05808.11 ORY33266.1 - 0.034 14.2 2.4 0.056 13.5 2.4 1.4 1 0 0 1 1 1 0 Podoplanin GnHR_trans PF12369.8 ORY33266.1 - 0.076 13.8 0.5 0.2 12.5 0.1 1.9 2 0 0 2 2 2 0 Gonadotropin hormone receptor transmembrane region Herpes_gE PF02480.16 ORY33267.1 - 0.0065 15.3 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 ORY33267.1 - 0.017 16.0 0.1 0.047 14.6 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 ORY33267.1 - 0.041 13.8 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF5305 PF17231.2 ORY33267.1 - 0.17 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5305) IBR PF01485.21 ORY33268.1 - 3.9e-12 46.2 5.2 5.3e-12 45.8 5.2 1.2 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain zf-C3HC4_4 PF15227.6 ORY33268.1 - 0.026 14.7 7.8 0.049 13.8 3.7 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RAG1 PF10426.9 ORY33268.1 - 0.054 13.6 0.0 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain IBR PF01485.21 ORY33269.1 - 8e-17 61.2 19.6 3.7e-11 43.1 4.0 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 ORY33269.1 - 0.00063 19.7 25.6 0.24 11.5 7.9 4.0 3 1 0 3 3 3 3 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY33269.1 - 0.028 14.3 32.1 0.85 9.5 3.2 5.1 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY33269.1 - 0.65 10.0 38.0 0.65 10.0 8.1 4.1 3 3 0 3 3 3 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY33269.1 - 3.4 7.6 34.8 0.74 9.7 5.4 4.7 3 2 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 ORY33269.1 - 6.6 6.8 20.5 29 4.8 0.1 4.3 2 1 0 2 2 2 0 Double zinc ribbon IBR PF01485.21 ORY33270.1 - 3.8e-15 55.8 37.9 1.2e-10 41.4 5.7 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 ORY33270.1 - 0.0073 16.3 31.0 0.29 11.1 6.5 4.2 3 2 0 3 3 3 3 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY33270.1 - 0.01 15.8 23.3 0.69 10.0 1.8 4.0 3 0 0 3 3 3 0 RING-type zinc-finger Vitelline_membr PF10542.9 ORY33270.1 - 0.012 15.5 2.2 0.036 13.9 2.2 1.8 1 0 0 1 1 1 0 Vitelline membrane cysteine-rich region zf-C3HC4 PF00097.25 ORY33270.1 - 0.08 12.8 38.9 1 9.3 3.4 5.1 3 2 2 5 5 5 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY33270.1 - 9.9 6.6 38.8 2.4 8.6 8.1 4.2 3 2 0 3 3 3 0 Ring finger domain CDH1_2_SANT_HL1 PF18375.1 ORY33271.1 - 0.00015 22.4 0.1 0.00038 21.1 0.0 1.7 2 0 0 2 2 2 1 CDH1/2 SANT-Helical linker 1 SLIDE PF09111.10 ORY33271.1 - 0.00027 21.0 0.0 0.00055 19.9 0.0 1.6 1 0 0 1 1 1 1 SLIDE CHDCT2 PF08074.11 ORY33271.1 - 0.00086 19.5 0.3 0.0024 18.1 0.1 1.8 2 0 0 2 2 2 1 CHDCT2 (NUC038) domain Cdh1_DBD_1 PF18196.1 ORY33271.1 - 0.01 16.1 0.2 0.058 13.7 0.0 2.0 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Myb_DNA-binding PF00249.31 ORY33271.1 - 0.19 12.0 0.1 0.19 12.0 0.1 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain peroxidase PF00141.23 ORY33272.1 - 4.9e-87 291.4 0.0 8.6e-47 159.7 0.0 2.2 2 0 0 2 2 2 2 Peroxidase DUF4097 PF13349.6 ORY33273.1 - 0.24 10.7 0.0 0.52 9.6 0.0 1.6 2 0 0 2 2 2 0 Putative adhesin EphA2_TM PF14575.6 ORY33275.1 - 0.033 15.1 0.1 0.71 10.8 0.1 2.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SKG6 PF08693.10 ORY33275.1 - 0.2 11.1 0.2 0.2 11.1 0.2 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF5060 PF16586.5 ORY33275.1 - 2.3 8.6 8.1 16 6.0 1.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5060) zf-CCCH PF00642.24 ORY33276.1 - 0.1 12.6 4.2 0.18 11.8 4.2 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ribosomal_S8 PF00410.19 ORY33277.1 - 4.5e-22 78.3 0.1 6.1e-22 77.9 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 SH3_1 PF00018.28 ORY33278.1 - 5.7e-08 32.2 0.0 1.1e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY33278.1 - 7.4e-08 32.1 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY33278.1 - 0.027 14.1 0.1 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Variant SH3 domain Fungal_KA1 PF16797.5 ORY33279.1 - 0.0088 15.7 0.6 0.014 15.1 0.6 1.5 1 1 0 1 1 1 1 Fungal kinase associated-1 domain Pkinase PF00069.25 ORY33280.1 - 5.7e-70 235.7 0.1 3.9e-69 232.9 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY33280.1 - 4.8e-38 130.9 0.0 1.6e-36 125.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY33280.1 - 0.0016 18.4 0.1 0.0035 17.3 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY33280.1 - 0.005 16.2 0.1 0.0071 15.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY33280.1 - 0.0086 15.4 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 ORY33280.1 - 0.05 13.2 0.0 0.088 12.4 0.0 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 ORY33280.1 - 0.088 11.7 0.3 0.17 10.8 0.3 1.3 1 1 0 1 1 1 0 Haspin like kinase domain RNA_pol_Rpb2_6 PF00562.28 ORY33281.1 - 1.1e-107 360.5 0.0 2.4e-107 359.4 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 ORY33281.1 - 5.2e-33 114.3 0.0 1.1e-32 113.2 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 ORY33281.1 - 3.1e-26 91.4 0.0 6.8e-26 90.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 ORY33281.1 - 6.8e-26 90.1 0.0 1.8e-25 88.7 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 ORY33281.1 - 2.1e-20 72.9 0.1 6.1e-20 71.4 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 ORY33281.1 - 1.2e-19 70.7 0.0 1.9e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 Filament PF00038.21 ORY33282.1 - 0.0081 15.8 0.3 0.01 15.5 0.3 1.0 1 0 0 1 1 1 1 Intermediate filament protein Fib_alpha PF08702.10 ORY33282.1 - 0.02 15.1 0.6 0.05 13.8 0.1 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 ORY33282.1 - 0.036 14.6 0.1 0.046 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Lebercilin PF15619.6 ORY33282.1 - 0.095 12.4 2.6 0.13 11.9 2.6 1.1 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DivIC PF04977.15 ORY33282.1 - 1.1 9.0 5.6 1.4 8.8 2.7 2.0 1 1 1 2 2 2 0 Septum formation initiator ABC_tran_CTD PF16326.5 ORY33282.1 - 1.4 9.2 5.4 7.1 7.0 5.4 2.0 1 1 0 1 1 1 0 ABC transporter C-terminal domain DUF4305 PF14146.6 ORY33283.1 - 5.5 7.3 11.0 6.8 7.0 1.8 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4305) 2OG-FeII_Oxy_2 PF13532.6 ORY33285.1 - 1.9e-30 106.5 0.0 2.1e-30 106.4 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3086 PF11285.8 ORY33285.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) PH PF00169.29 ORY33286.1 - 0.055 14.0 0.9 3.1 8.4 0.9 2.6 1 1 0 1 1 1 0 PH domain PAN_1 PF00024.26 ORY33287.1 - 2.6e-31 107.4 63.6 1.9e-07 30.9 0.2 10.9 7 2 4 11 11 11 9 PAN domain PAN_4 PF14295.6 ORY33287.1 - 6.2e-22 77.2 62.6 0.00037 20.3 1.8 10.7 9 1 1 10 10 10 9 PAN domain PAN_3 PF08277.12 ORY33287.1 - 4.9e-17 61.5 64.7 0.0001 22.1 1.3 10.1 8 1 1 9 9 9 8 PAN-like domain MANEC PF07502.14 ORY33287.1 - 2.3e-09 37.4 46.7 0.0037 17.5 0.2 10.5 10 0 0 10 10 10 6 MANEC domain Pacifastin_I PF05375.13 ORY33287.1 - 2 8.2 16.5 0.48 10.2 0.3 3.7 4 0 0 4 4 4 0 Pacifastin inhibitor (LCMII) DUF4786 PF16027.5 ORY33287.1 - 5.9 7.4 5.5 4.3 7.9 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4786) PAN_2 PF08276.11 ORY33287.1 - 9 6.5 69.7 0.57 10.3 1.1 10.0 9 1 1 10 10 10 0 PAN-like domain Sulf_transp PF04143.14 ORY33288.1 - 2.1e-32 112.9 26.6 2.1e-32 112.9 26.6 1.7 2 0 0 2 2 2 1 Sulphur transport Aconitase PF00330.20 ORY33290.1 - 1.8e-151 505.3 0.0 2.3e-151 504.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORY33290.1 - 8.7e-43 145.8 0.0 1.6e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain THB PF18362.1 ORY33290.1 - 0.19 11.4 0.5 0.49 10.0 0.1 1.9 2 0 0 2 2 2 0 Tri-helix bundle domain DER1 PF04511.15 ORY33291.1 - 7.7e-56 189.1 5.6 9.7e-56 188.7 5.6 1.1 1 0 0 1 1 1 1 Der1-like family Rhomboid PF01694.22 ORY33291.1 - 1.2e-05 25.4 8.2 1.7e-05 24.9 8.2 1.2 1 0 0 1 1 1 1 Rhomboid family Tyr-DNA_phospho PF06087.12 ORY33294.1 - 2.5e-65 221.1 0.1 3.3e-65 220.7 0.1 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 ORY33294.1 - 0.00035 20.5 0.0 0.052 13.4 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain SNARE PF05739.19 ORY33523.1 - 7.5e-16 57.9 2.8 2.7e-15 56.1 0.2 2.4 2 1 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 ORY33523.1 - 5.1e-06 26.3 10.7 1.5e-05 24.8 10.7 1.7 1 1 0 1 1 1 1 Syntaxin Syntaxin_2 PF14523.6 ORY33523.1 - 0.0036 17.6 12.4 0.048 14.0 6.5 3.0 2 1 1 3 3 3 1 Syntaxin-like protein Orf78 PF06024.12 ORY33523.1 - 0.09 13.1 2.8 0.25 11.7 0.2 2.4 2 0 0 2 2 2 0 Orf78 (ac78) Prominin PF05478.11 ORY33523.1 - 0.097 10.6 6.3 0.32 8.9 6.4 1.8 1 1 0 1 1 1 0 Prominin MtrG PF04210.13 ORY33523.1 - 0.097 12.5 0.2 0.097 12.5 0.2 3.2 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Mid2 PF04478.12 ORY33523.1 - 0.11 12.4 0.4 1.2 8.9 0.1 2.2 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor NPV_P10 PF05531.12 ORY33523.1 - 0.2 12.2 4.0 5.9 7.4 0.3 3.5 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DNA_repr_REX1B PF14966.6 ORY33523.1 - 0.25 12.0 4.0 0.18 12.5 1.2 2.3 2 1 0 2 2 2 0 DNA repair REX1-B DUF16 PF01519.16 ORY33523.1 - 0.33 11.5 12.6 0.2 12.2 1.9 2.6 2 1 0 2 2 2 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 ORY33523.1 - 0.64 10.1 5.8 4.6 7.3 0.3 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2203 PF09969.9 ORY33523.1 - 0.71 10.6 6.9 9.7 6.9 0.5 2.6 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) BLOC1_2 PF10046.9 ORY33523.1 - 0.93 9.8 9.6 1.6 9.1 2.6 3.3 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CorA PF01544.18 ORY33523.1 - 1.7 7.9 10.2 1.9 7.7 1.3 2.4 2 1 0 2 2 2 0 CorA-like Mg2+ transporter protein MCPsignal PF00015.21 ORY33523.1 - 2.2 8.1 10.1 1.1 9.1 0.4 3.0 2 2 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain PspA_IM30 PF04012.12 ORY33523.1 - 2.2 7.8 14.2 0.13 11.8 2.2 2.9 2 1 1 3 3 3 0 PspA/IM30 family ISG65-75 PF11727.8 ORY33523.1 - 2.4 7.3 7.6 1.1 8.5 1.1 2.2 2 0 0 2 2 2 0 Invariant surface glycoprotein Synaptobrevin PF00957.21 ORY33523.1 - 2.7 7.9 7.0 0.37 10.6 1.8 2.4 2 1 0 2 2 2 0 Synaptobrevin Prefoldin_2 PF01920.20 ORY33523.1 - 3.6 7.6 8.8 1.7 8.6 0.2 3.3 3 1 0 3 3 3 0 Prefoldin subunit SlyX PF04102.12 ORY33523.1 - 6 7.6 10.0 2.4 8.8 0.5 4.1 3 1 1 4 4 4 0 SlyX Amnionless PF14828.6 ORY33523.1 - 7.2 5.3 6.6 11 4.7 0.3 2.1 1 1 1 2 2 2 0 Amnionless Birna_VP4 PF01768.16 ORY33524.1 - 0.11 12.2 0.3 11 5.7 0.0 2.1 2 0 0 2 2 2 0 Birnavirus VP4 protein JmjC PF02373.22 ORY33525.1 - 7e-42 142.5 0.6 9.5e-42 142.0 0.6 1.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase MAT1 PF06391.13 ORY33526.1 - 1.1e-47 162.5 19.8 1.4e-47 162.2 19.8 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 ORY33526.1 - 0.0014 18.5 1.8 0.0024 17.7 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PPL4 PF18188.1 ORY33526.1 - 0.11 12.5 0.8 0.2 11.6 0.8 1.4 1 0 0 1 1 1 0 Prim-pol 4 zf-RING_5 PF14634.6 ORY33526.1 - 0.23 11.5 1.3 0.35 10.8 1.3 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY33526.1 - 0.28 11.1 1.2 0.41 10.6 1.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF572 PF04502.13 ORY33526.1 - 2.8 7.5 13.2 3.8 7.0 13.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) MCM PF00493.23 ORY33527.1 - 4e-103 343.3 0.0 6.5e-103 342.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY33527.1 - 5.3e-33 113.5 0.2 1.1e-32 112.5 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORY33527.1 - 2.6e-19 69.4 0.1 9.4e-19 67.6 0.1 2.1 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 ORY33527.1 - 3.4e-13 50.1 2.0 2.8e-12 47.1 1.3 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 ORY33527.1 - 3.8e-07 29.7 0.1 0.00031 20.2 0.0 2.7 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ORY33527.1 - 1.1e-05 25.5 0.0 3.7e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ORY33527.1 - 0.00012 21.9 0.0 0.0004 20.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF134 PF02001.16 ORY33527.1 - 0.018 15.6 0.1 1.4 9.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function DUF134 Sigma54_activat PF00158.26 ORY33527.1 - 0.026 14.2 0.0 0.79 9.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.6 ORY33527.1 - 0.17 12.3 0.7 2.9 8.3 0.0 2.8 2 1 0 3 3 3 0 AAA ATPase domain RB_B PF01857.20 ORY33528.1 - 2.3e-13 50.3 1.0 4.2e-13 49.5 0.3 1.8 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain RB_A PF01858.17 ORY33528.1 - 0.0028 17.5 9.6 0.004 17.0 3.6 3.4 3 1 0 3 3 3 1 Retinoblastoma-associated protein A domain PP1 PF07430.11 ORY33528.1 - 0.038 14.1 0.5 0.1 12.6 0.5 1.8 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain RPA_interact_C PF14768.6 ORY33528.1 - 0.066 13.8 0.4 3 8.5 0.0 3.1 3 0 0 3 3 3 0 Replication protein A interacting C-terminal AAA PF00004.29 ORY33529.1 - 1.5e-45 154.8 0.1 5.7e-35 120.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY33529.1 - 1e-08 35.8 4.1 0.0064 16.9 0.5 3.7 2 2 0 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 ORY33529.1 - 1.8e-07 31.0 0.0 3.6e-05 23.5 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 ORY33529.1 - 5.4e-07 29.5 1.8 0.0079 15.9 0.0 3.1 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.14 ORY33529.1 - 9.2e-07 28.9 0.0 0.035 14.1 0.0 3.0 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 ORY33529.1 - 2e-06 27.3 0.7 2.5e-05 23.7 0.2 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain ABC_tran PF00005.27 ORY33529.1 - 4.6e-06 27.2 0.2 0.11 13.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ATPase_2 PF01637.18 ORY33529.1 - 2e-05 24.7 0.1 0.15 11.9 0.0 2.6 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 ORY33529.1 - 3.2e-05 24.3 0.0 0.12 12.8 0.1 2.7 2 1 0 2 2 2 2 RNA helicase AAA_22 PF13401.6 ORY33529.1 - 6.5e-05 23.2 7.2 0.063 13.6 0.3 4.3 3 2 2 5 5 4 1 AAA domain AAA_18 PF13238.6 ORY33529.1 - 7.2e-05 23.3 0.0 0.11 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 ORY33529.1 - 9.4e-05 22.5 0.0 0.25 11.4 0.0 2.7 3 0 0 3 3 3 2 AAA domain Hpr_kinase_C PF07475.12 ORY33529.1 - 0.00013 21.6 0.3 0.18 11.3 0.1 2.4 2 0 0 2 2 2 2 HPr Serine kinase C-terminal domain AAA_33 PF13671.6 ORY33529.1 - 0.0002 21.6 0.0 0.027 14.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ORY33529.1 - 0.00024 21.0 0.3 0.23 11.4 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase IstB_IS21 PF01695.17 ORY33529.1 - 0.00029 20.6 0.1 0.051 13.3 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_29 PF13555.6 ORY33529.1 - 0.00045 19.9 0.3 0.081 12.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ORY33529.1 - 0.00058 19.5 0.6 8.9 5.8 0.0 3.7 4 0 0 4 4 4 0 AAA domain Bac_DnaA PF00308.18 ORY33529.1 - 0.0008 19.3 0.0 1.5 8.6 0.0 2.3 2 0 0 2 2 2 2 Bacterial dnaA protein Sigma54_activat PF00158.26 ORY33529.1 - 0.0009 19.0 0.1 0.26 11.0 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_2 PF07724.14 ORY33529.1 - 0.00094 19.3 0.0 0.044 13.9 0.0 2.7 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) NACHT PF05729.12 ORY33529.1 - 0.0022 17.9 2.9 3.3 7.6 0.1 3.6 3 1 0 3 3 3 2 NACHT domain AAA_7 PF12775.7 ORY33529.1 - 0.0022 17.5 0.5 1.8 8.0 0.1 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region Guanylate_kin PF00625.21 ORY33529.1 - 0.011 15.5 0.8 1 9.0 0.0 3.1 2 1 2 4 4 4 0 Guanylate kinase TsaE PF02367.17 ORY33529.1 - 0.014 15.4 0.2 0.34 10.9 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 ORY33529.1 - 0.019 14.2 0.1 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 ORY33529.1 - 0.02 15.3 0.1 0.15 12.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 ORY33529.1 - 0.026 13.7 0.2 3.1 6.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SMC_N PF02463.19 ORY33529.1 - 0.028 13.9 1.3 0.056 12.9 0.0 2.2 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain IPT PF01745.16 ORY33529.1 - 0.035 13.5 0.2 0.13 11.6 0.0 2.0 3 0 0 3 3 3 0 Isopentenyl transferase NTPase_1 PF03266.15 ORY33529.1 - 0.037 13.9 0.3 3.7 7.5 0.1 2.4 2 0 0 2 2 2 0 NTPase AAA_21 PF13304.6 ORY33529.1 - 0.041 13.7 0.0 4.2 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DEAD PF00270.29 ORY33529.1 - 0.067 13.0 0.8 52 3.5 0.0 3.3 2 1 1 3 3 3 0 DEAD/DEAH box helicase AAA_28 PF13521.6 ORY33529.1 - 0.099 12.9 0.0 8.9 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 ORY33529.1 - 0.2 10.8 0.3 10 5.2 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain AFG1_ATPase PF03969.16 ORY33529.1 - 0.22 10.4 0.0 2.4 6.9 0.0 2.0 2 0 0 2 2 2 0 AFG1-like ATPase Glyco_transf_20 PF00982.21 ORY33530.1 - 4.9e-130 434.4 0.7 9e-130 433.5 0.7 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 ORY33530.1 - 7.7e-49 165.9 0.2 1.9e-43 148.3 0.0 2.7 2 1 0 2 2 2 2 Trehalose-phosphatase Hydrolase_3 PF08282.12 ORY33530.1 - 0.0065 16.2 0.0 15 5.2 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Symplekin_C PF12295.8 ORY33531.1 - 1.3e-40 139.5 3.0 1.3e-40 139.5 3.0 2.8 4 0 0 4 4 4 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 ORY33531.1 - 1.1e-21 77.5 0.0 2.5e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) CLASP_N PF12348.8 ORY33531.1 - 0.018 14.6 0.9 0.091 12.3 0.3 2.2 2 0 0 2 2 2 0 CLASP N terminal Radical_SAM_C PF16199.5 ORY33531.1 - 0.05 13.6 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Radical_SAM C-terminal domain DUF676 PF05057.14 ORY33532.1 - 8.4e-42 143.2 0.0 1.7e-41 142.1 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 ORY33532.1 - 6.6e-07 29.3 0.0 2.6e-06 27.3 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Palm_thioest PF02089.15 ORY33532.1 - 3.9e-06 26.9 0.0 2.2e-05 24.4 0.0 2.0 2 1 0 2 2 2 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 ORY33532.1 - 0.093 13.3 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3767 PF12597.8 ORY33534.1 - 9.9e-21 73.5 0.0 1.3e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) PBP_like_2 PF12849.7 ORY33535.1 - 6.5e-15 55.6 0.1 8.1e-15 55.2 0.1 1.1 1 0 0 1 1 1 1 PBP superfamily domain 7tm_3 PF00003.22 ORY33536.1 - 1e-22 81.0 11.4 1.6e-22 80.4 11.4 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR PBP_like_2 PF12849.7 ORY33537.1 - 5.4e-13 49.3 0.1 6.5e-13 49.0 0.1 1.0 1 0 0 1 1 1 1 PBP superfamily domain PBP_like_2 PF12849.7 ORY33538.1 - 0.079 12.6 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 PBP superfamily domain Pyr_redox_2 PF07992.14 ORY33540.1 - 4e-39 134.6 0.0 6.3e-20 71.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY33540.1 - 0.00012 22.5 0.0 0.025 15.1 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY33540.1 - 0.0011 18.1 0.0 0.015 14.4 0.0 2.5 3 0 0 3 3 3 1 FAD binding domain DUF4788 PF16032.5 ORY33540.1 - 0.15 11.0 0.0 0.31 10.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4788) Alg6_Alg8 PF03155.15 ORY33541.1 - 9.6e-172 572.3 25.3 1.2e-171 572.0 25.3 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family PCI PF01399.27 ORY33542.1 - 3.3e-18 66.1 0.0 9.7e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 PCI domain CSN4_RPN5_eIF3a PF18420.1 ORY33542.1 - 0.036 14.2 0.0 0.079 13.1 0.0 1.5 1 0 0 1 1 1 0 CSN4/RPN5/eIF3a helix turn helix domain 7tm_3 PF00003.22 ORY33543.1 - 1.6e-17 64.1 9.3 3.3e-17 63.0 9.3 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR PBP_like_2 PF12849.7 ORY33543.1 - 2.2e-14 53.8 3.9 3.4e-14 53.2 3.9 1.2 1 0 0 1 1 1 1 PBP superfamily domain 7TMR-DISM_7TM PF07695.11 ORY33543.1 - 0.0072 16.2 3.6 0.0072 16.2 3.6 3.0 3 1 0 3 3 3 1 7TM diverse intracellular signalling MSC PF09402.10 ORY33544.1 - 4.5e-08 32.9 0.6 4.5e-08 32.9 0.6 1.8 2 0 0 2 2 2 1 Man1-Src1p-C-terminal domain zf-MYND PF01753.18 ORY33545.1 - 6e-07 29.4 12.9 6e-07 29.4 12.9 2.4 2 1 0 2 2 2 1 MYND finger bZIP_1 PF00170.21 ORY33546.1 - 0.00097 19.2 20.7 0.0027 17.8 4.8 4.2 5 0 0 5 5 5 2 bZIP transcription factor TSC22 PF01166.18 ORY33546.1 - 0.001 19.3 2.6 1.7 9.0 0.0 3.7 3 0 0 3 3 3 2 TSC-22/dip/bun family zf-C4pol PF14260.6 ORY33546.1 - 0.0084 16.5 0.3 0.028 14.9 0.3 1.9 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta GAS PF13851.6 ORY33546.1 - 0.046 13.1 2.5 0.72 9.2 1.0 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding PhaP_Bmeg PF09602.10 ORY33546.1 - 0.095 12.6 1.7 4.4 7.2 0.4 2.4 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) TPR_MLP1_2 PF07926.12 ORY33546.1 - 2.7 8.0 9.4 2.5 8.2 0.1 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 ORY33546.1 - 4.3 7.2 6.9 29 4.5 3.1 2.8 3 0 0 3 3 3 0 Septum formation initiator DUF5094 PF17015.5 ORY33546.1 - 4.3 7.4 7.8 1.5 8.9 2.6 2.5 2 1 0 3 3 3 0 Domain of unknown function (DUF5094) CDC45 PF02724.14 ORY33547.1 - 0.00064 18.2 17.9 0.00067 18.1 17.9 1.1 1 0 0 1 1 1 1 CDC45-like protein BUD22 PF09073.10 ORY33547.1 - 0.019 14.3 20.6 0.021 14.2 20.6 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 ORY33547.1 - 0.19 9.9 26.9 0.22 9.7 26.9 1.1 1 0 0 1 1 1 0 Nop14-like family Afi1 PF07792.12 ORY33547.1 - 0.6 10.6 15.6 0.085 13.3 10.2 2.1 1 1 1 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF913 PF06025.12 ORY33547.1 - 1.1 8.2 4.4 1.3 8.0 4.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2151 PF10221.9 ORY33547.1 - 1.7 7.1 3.7 2 6.9 3.7 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Zip PF02535.22 ORY33547.1 - 1.8 7.7 2.9 2.1 7.5 2.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.15 ORY33547.1 - 2.5 6.8 12.1 3.1 6.5 12.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Tim54 PF11711.8 ORY33547.1 - 3.9 6.1 7.7 0.81 8.4 4.3 1.5 1 1 1 2 2 2 0 Inner membrane protein import complex subunit Tim54 CobT PF06213.12 ORY33547.1 - 4.3 6.7 21.1 6.4 6.1 21.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Presenilin PF01080.17 ORY33547.1 - 5.9 5.6 4.5 7.5 5.2 4.5 1.1 1 0 0 1 1 1 0 Presenilin PTPRCAP PF15713.5 ORY33547.1 - 6.6 7.0 20.8 12 6.2 20.8 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF2722 PF10846.8 ORY33547.1 - 9.5 5.0 18.2 16 4.3 18.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2340 PF10209.9 ORY33548.1 - 6e-44 149.3 0.3 6.9e-44 149.1 0.3 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Peptidase_M24 PF00557.24 ORY33549.1 - 7.6e-37 127.0 0.4 7.9e-36 123.7 0.4 2.1 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 ORY33549.1 - 2.9e-07 30.2 0.0 6.8e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain 7tm_3 PF00003.22 ORY33550.1 - 3.3e-10 40.1 4.1 5.5e-10 39.4 4.1 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR PBP_like_2 PF12849.7 ORY33551.1 - 7.4e-15 55.4 1.5 1e-14 54.9 1.5 1.1 1 0 0 1 1 1 1 PBP superfamily domain Radical_SAM_C PF16199.5 ORY33552.1 - 1.6e-31 108.2 0.0 3.4e-31 107.1 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 ORY33552.1 - 7.2e-11 42.7 0.0 4.1e-10 40.3 0.0 2.3 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 ORY33552.1 - 9.1e-11 42.0 0.0 1.7e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY33552.1 - 4.4e-06 26.6 0.0 1.2e-05 25.3 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY33552.1 - 0.0025 18.2 0.0 0.0048 17.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY33552.1 - 0.015 15.3 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein WD40 PF00400.32 ORY33553.1 - 1.4e-37 127.0 25.9 1.2e-09 38.6 0.4 7.8 7 1 1 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY33553.1 - 1.8e-14 53.8 6.4 7.7e-05 22.9 0.0 5.3 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY33553.1 - 0.00095 18.6 0.8 0.52 9.6 0.6 2.8 2 1 1 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 ORY33553.1 - 0.0036 16.3 3.3 0.031 13.2 1.2 2.9 2 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 ORY33553.1 - 0.032 13.2 6.2 5.7 5.7 0.4 4.1 1 1 5 6 6 6 0 Partner and localizer of BRCA2 WD40 domain NosD PF05048.13 ORY33553.1 - 0.13 11.5 0.4 0.77 9.0 0.7 2.2 2 1 0 2 2 2 0 Periplasmic copper-binding protein (NosD) DUF4452 PF14618.6 ORY33553.1 - 0.21 11.5 0.3 0.37 10.6 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) GST_N_2 PF13409.6 ORY33554.1 - 6.6e-14 52.0 0.1 1.9e-12 47.3 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY33554.1 - 1e-12 48.3 0.0 5e-12 46.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY33554.1 - 5.7e-10 39.4 0.2 3.5e-09 36.9 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 ORY33554.1 - 3.4e-06 27.6 0.0 4.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY33554.1 - 9.4e-06 25.6 0.1 1.5e-05 24.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY33554.1 - 0.0018 18.5 0.0 0.0029 17.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY33554.1 - 0.054 13.7 0.0 0.087 13.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DEAD PF00270.29 ORY33555.1 - 2.5e-45 154.4 0.5 2.5e-45 154.4 0.5 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY33555.1 - 1.5e-33 115.4 0.3 3.6e-32 111.0 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY33555.1 - 1.1e-06 28.8 0.0 1.9e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 ORY33555.1 - 0.00013 22.3 0.9 0.0027 18.1 0.2 2.5 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY33555.1 - 0.0015 18.3 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain tRNA-synt_1b PF00579.25 ORY33555.1 - 0.015 14.6 0.0 0.31 10.3 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) CMS1 PF14617.6 ORY33555.1 - 0.019 14.3 0.6 0.052 12.9 0.0 2.0 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 ORY33555.1 - 0.064 13.5 0.2 0.31 11.3 0.2 2.1 1 1 0 1 1 1 0 AAA domain UTP25 PF06862.12 ORY33555.1 - 0.083 11.6 0.3 7.9 5.1 0.0 2.2 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Flavi_DEAD PF07652.14 ORY33555.1 - 0.1 12.6 0.0 0.84 9.6 0.0 2.3 2 0 0 2 2 2 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 ORY33555.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Helicase Ras PF00071.22 ORY33556.1 - 2.2e-65 219.2 1.0 2.6e-65 218.9 1.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY33556.1 - 2.4e-36 124.6 0.2 4e-36 123.8 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY33556.1 - 8.2e-18 64.4 0.4 1.1e-17 64.1 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY33556.1 - 1.6e-05 24.5 1.0 3.8e-05 23.3 0.6 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY33556.1 - 1.9e-05 24.6 0.7 0.13 12.2 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ORY33556.1 - 2.1e-05 24.6 0.0 3.8e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORY33556.1 - 2.5e-05 23.7 0.1 2.8e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 ORY33556.1 - 2.9e-05 23.6 0.1 3.6e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 ORY33556.1 - 0.0078 15.7 0.1 0.056 13.0 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 ORY33556.1 - 0.0083 16.5 0.0 0.012 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ORY33556.1 - 0.011 15.7 0.0 0.023 14.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 ORY33556.1 - 0.024 15.0 0.2 0.54 10.7 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 ORY33556.1 - 0.035 13.8 0.0 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_7 PF12775.7 ORY33556.1 - 0.039 13.5 0.0 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 ORY33556.1 - 0.041 13.6 0.1 1.3 8.8 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 ORY33556.1 - 0.047 13.9 0.0 0.085 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 ORY33556.1 - 0.054 12.8 0.1 0.16 11.2 0.0 1.8 2 1 0 2 2 2 0 Septin TniB PF05621.11 ORY33556.1 - 0.084 12.3 0.0 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.27 ORY33556.1 - 0.088 13.3 0.0 0.14 12.7 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 ORY33556.1 - 0.15 11.7 0.2 1.2 8.7 0.2 2.3 1 1 0 1 1 1 0 AAA domain EnY2 PF10163.9 ORY33557.1 - 1.2e-30 105.7 1.2 1.4e-30 105.5 1.2 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 WD40 PF00400.32 ORY33558.1 - 4.5e-29 100.1 13.7 1.4e-07 32.1 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY33558.1 - 2.8e-09 37.1 0.0 0.44 10.9 0.0 4.7 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Striatin PF08232.12 ORY33558.1 - 0.00022 21.8 5.1 0.0016 19.0 0.0 2.4 2 0 0 2 2 2 1 Striatin family Smg4_UPF3 PF03467.15 ORY33559.1 - 3.1e-45 154.3 0.5 3.9e-45 154.0 0.5 1.1 1 0 0 1 1 1 1 Smg-4/UPF3 family DUF4121 PF13497.6 ORY33559.1 - 0.058 12.5 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) COX6B PF02297.17 ORY33560.1 - 0.00061 20.0 1.2 0.001 19.3 1.2 1.4 1 1 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.13 ORY33560.1 - 0.003 17.7 1.5 0.0067 16.5 1.5 1.6 1 1 0 1 1 1 1 CHCH domain CX9C PF16860.5 ORY33560.1 - 0.091 12.8 0.5 0.45 10.6 0.1 2.0 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Inv-AAD PF18785.1 ORY33561.1 - 5.8e-28 97.3 0.8 4.5e-27 94.5 0.8 1.9 1 1 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 ORY33561.1 - 1.8e-17 63.1 0.0 2.2e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY33561.1 - 0.0019 17.9 0.0 0.0026 17.5 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase XOO_2897-deam PF14440.6 ORY33561.1 - 0.0022 18.1 0.1 0.003 17.7 0.1 1.2 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase APOBEC_N PF08210.11 ORY33561.1 - 0.009 15.9 0.0 0.015 15.2 0.0 1.4 2 0 0 2 2 2 1 APOBEC-like N-terminal domain MFS_1 PF07690.16 ORY33562.1 - 1e-12 47.7 23.3 1.5e-12 47.1 23.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY33562.1 - 0.0054 16.5 16.1 0.061 13.0 0.0 3.6 4 0 0 4 4 4 2 Ion channel regulatory protein UNC-93 MSC PF09402.10 ORY33563.1 - 2e-05 24.2 0.2 2e-05 24.2 0.2 2.0 3 0 0 3 3 3 1 Man1-Src1p-C-terminal domain Thymopoietin PF08198.11 ORY33563.1 - 0.00014 21.4 0.0 0.00068 19.2 0.0 2.2 2 0 0 2 2 2 1 Thymopoietin protein HeH PF12949.7 ORY33563.1 - 0.00029 20.5 0.0 0.00079 19.1 0.0 1.8 1 0 0 1 1 1 1 HeH/LEM domain GP46 PF07409.12 ORY33565.1 - 0.17 11.7 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Phage protein GP46 Helitron_like_N PF14214.6 ORY33566.1 - 7.6e-08 32.8 0.0 9.1e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF4368 PF14287.6 ORY33566.1 - 0.0037 17.5 0.1 0.0095 16.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4368) DUF2102 PF09875.9 ORY33566.1 - 0.088 12.5 0.0 0.15 11.8 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) AAA_30 PF13604.6 ORY33568.1 - 4.6e-14 52.6 0.0 4.8e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 ORY33568.1 - 1.3e-13 50.9 0.0 1.4e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 ORY33568.1 - 9.1e-12 45.5 0.1 1.8e-11 44.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 ORY33568.1 - 9.3e-06 24.8 0.0 1.1e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 ORY33568.1 - 0.00025 20.6 0.0 0.00031 20.3 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ATP_bind_1 PF03029.17 ORY33568.1 - 0.00035 20.4 0.0 0.0004 20.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 ORY33568.1 - 0.00035 20.5 0.1 0.14 12.1 0.0 2.1 2 0 0 2 2 2 1 NTPase AAA_14 PF13173.6 ORY33568.1 - 0.00078 19.5 0.0 0.0016 18.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORY33568.1 - 0.0011 18.6 0.1 0.002 17.8 0.1 1.5 1 1 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 ORY33568.1 - 0.0016 18.8 0.0 0.0034 17.7 0.0 1.6 1 1 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 ORY33568.1 - 0.0018 18.7 0.0 0.0019 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 ORY33568.1 - 0.0018 18.3 0.0 0.0052 16.8 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY33568.1 - 0.0023 18.2 0.5 0.019 15.3 0.5 2.0 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 ORY33568.1 - 0.0043 16.8 0.3 0.0093 15.7 0.3 1.6 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase APS_kinase PF01583.20 ORY33568.1 - 0.0052 16.7 0.2 0.012 15.5 0.2 1.6 1 1 0 1 1 1 1 Adenylylsulphate kinase DUF463 PF04317.12 ORY33568.1 - 0.011 14.8 0.1 0.012 14.6 0.1 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_11 PF13086.6 ORY33568.1 - 0.014 15.2 0.4 0.099 12.4 0.0 1.9 1 1 1 2 2 2 0 AAA domain T2SSE PF00437.20 ORY33568.1 - 0.017 14.2 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 ORY33568.1 - 0.02 14.6 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ORY33568.1 - 0.02 14.9 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 ORY33568.1 - 0.023 14.0 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.19 ORY33568.1 - 0.033 13.8 0.2 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Helicase_RecD PF05127.14 ORY33568.1 - 0.041 13.7 0.5 0.95 9.3 0.5 2.1 1 1 0 1 1 1 0 Helicase ATPase_2 PF01637.18 ORY33568.1 - 0.05 13.5 0.6 1.9 8.3 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 ORY33568.1 - 0.053 13.0 0.3 0.29 10.6 0.2 2.0 1 1 1 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 ORY33568.1 - 0.068 13.6 0.0 0.097 13.1 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 ORY33568.1 - 0.07 12.8 0.1 0.11 12.1 0.1 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain G-alpha PF00503.20 ORY33568.1 - 0.087 12.0 0.0 0.087 12.0 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit TniB PF05621.11 ORY33568.1 - 0.09 12.2 0.1 0.66 9.4 0.0 2.1 2 1 1 3 3 3 0 Bacterial TniB protein DUF2075 PF09848.9 ORY33568.1 - 0.093 11.9 0.2 0.13 11.5 0.2 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 ORY33568.1 - 0.11 13.1 0.4 0.16 12.5 0.4 1.5 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 ORY33568.1 - 0.14 11.8 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase ETC_C1_NDUFA4 PF04800.12 ORY33571.1 - 3e-32 110.7 0.2 4.1e-32 110.3 0.2 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region Shadoo PF14999.6 ORY33571.1 - 0.53 10.4 6.7 1.8 8.7 6.7 1.7 1 1 0 1 1 1 0 Shadow of prion protein, neuroprotective Metallophos PF00149.28 ORY33572.1 - 0.00029 21.4 0.0 0.0016 19.0 0.0 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Big_7 PF17957.1 ORY33572.1 - 0.054 14.3 0.0 0.14 12.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial Ig domain zf-piccolo PF05715.13 ORY33573.1 - 1.9e-05 24.7 0.3 2.8e-05 24.2 0.3 1.2 1 0 0 1 1 1 1 Piccolo Zn-finger zf-C3HC4_3 PF13920.6 ORY33573.1 - 0.0048 16.7 1.6 0.0091 15.8 0.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CHC2 PF01807.20 ORY33573.1 - 0.025 14.4 1.0 0.81 9.5 0.7 2.0 1 1 1 2 2 2 0 CHC2 zinc finger Prok-RING_4 PF14447.6 ORY33573.1 - 3.6 7.5 8.9 5.3 7.0 0.6 2.9 1 1 2 3 3 3 0 Prokaryotic RING finger family 4 AAA_6 PF12774.7 ORY33574.1 - 4.4e-161 535.3 0.0 9.9e-160 530.9 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 ORY33574.1 - 1e-136 456.2 3.0 1e-136 456.2 3.0 3.4 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 ORY33574.1 - 1.2e-106 355.9 0.0 3.9e-106 354.2 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 ORY33574.1 - 1.3e-102 343.2 0.1 1.3e-100 336.6 0.0 3.3 4 0 0 4 4 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 ORY33574.1 - 1.6e-94 315.1 0.9 1.6e-94 315.1 0.9 2.7 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 ORY33574.1 - 9e-76 253.4 0.1 3.7e-70 235.1 0.0 4.1 5 0 0 5 5 5 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 ORY33574.1 - 3.9e-55 186.1 0.0 1.5e-54 184.2 0.0 2.1 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 ORY33574.1 - 1.3e-50 172.4 16.7 2.9e-50 171.3 16.7 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 ORY33574.1 - 4.4e-43 146.2 0.2 6.9e-40 135.8 0.0 4.5 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 ORY33574.1 - 1.1e-25 90.2 2.9 6.8e-25 87.6 0.2 4.0 4 0 0 4 4 3 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 ORY33574.1 - 6.4e-19 68.0 0.5 5.3e-18 65.1 0.0 2.8 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 ORY33574.1 - 4.2e-17 62.4 0.0 0.00064 19.7 0.0 5.5 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 ORY33574.1 - 4.6e-07 30.3 0.6 0.017 15.5 0.0 4.4 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY33574.1 - 1.6e-06 28.6 0.0 0.59 10.5 0.1 5.5 4 1 1 5 5 5 2 AAA ATPase domain AAA_18 PF13238.6 ORY33574.1 - 7.3e-05 23.3 0.1 0.0094 16.5 0.0 3.9 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 ORY33574.1 - 0.002 18.5 0.2 3.5 8.1 0.0 3.5 3 0 0 3 3 3 1 RNA helicase AAA_30 PF13604.6 ORY33574.1 - 0.0048 16.6 0.4 0.96 9.1 0.1 3.6 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 ORY33574.1 - 0.0057 15.8 0.0 0.79 8.7 0.0 3.4 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_22 PF13401.6 ORY33574.1 - 0.053 13.8 1.8 13 6.1 0.0 4.6 4 0 0 4 4 3 0 AAA domain AAA_25 PF13481.6 ORY33574.1 - 0.058 13.0 0.1 2.1 7.9 0.0 3.0 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 ORY33574.1 - 0.089 12.7 0.1 23 4.9 0.0 3.1 2 0 0 2 2 2 0 Rad17 P-loop domain BORCS6 PF10157.9 ORY33574.1 - 0.12 12.6 0.9 1.2 9.4 0.4 2.9 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 6 Sec2p PF06428.11 ORY33574.1 - 3.3 7.7 7.9 8.8 6.4 2.9 3.4 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Mod_r PF07200.13 ORY33574.1 - 9.1 6.4 11.7 1.1 9.4 5.1 3.0 2 0 0 2 2 1 0 Modifier of rudimentary (Mod(r)) protein HAUS4 PF14735.6 ORY33577.1 - 2.8e-14 53.4 5.2 3.5e-14 53.1 5.2 1.1 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 DUF4407 PF14362.6 ORY33577.1 - 0.00063 19.2 0.6 0.00075 18.9 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) CENP-Q PF13094.6 ORY33577.1 - 0.0051 17.0 1.3 0.0098 16.1 1.3 1.5 1 1 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DASH_Dad1 PF08649.10 ORY33577.1 - 0.0065 16.6 0.0 6.4 7.1 0.0 2.7 2 0 0 2 2 2 2 DASH complex subunit Dad1 FlgN PF05130.12 ORY33577.1 - 0.0093 16.5 0.8 0.0093 16.5 0.8 2.0 2 0 0 2 2 2 1 FlgN protein DLP_helical PF18709.1 ORY33577.1 - 0.019 14.2 2.5 0.049 12.8 0.6 2.1 2 0 0 2 2 2 0 Dynamin-like helical domain DUF1664 PF07889.12 ORY33577.1 - 0.074 13.1 3.7 5.4 7.1 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) ATP-synt_D PF01813.17 ORY33577.1 - 0.21 11.4 3.0 0.71 9.7 3.0 1.9 1 1 0 1 1 1 0 ATP synthase subunit D KfrA_N PF11740.8 ORY33577.1 - 0.23 12.1 5.8 0.11 13.1 2.2 2.2 3 0 0 3 3 2 0 Plasmid replication region DNA-binding N-term Occludin_ELL PF07303.13 ORY33577.1 - 0.48 11.2 4.4 13 6.6 1.0 2.8 2 1 0 2 2 2 0 Occludin homology domain Baculo_PEP_C PF04513.12 ORY33577.1 - 0.69 9.9 7.1 0.55 10.3 1.5 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.15 ORY33577.1 - 0.78 9.2 5.0 1 8.9 4.9 1.3 1 1 0 1 1 1 0 Exonuclease VII, large subunit Uso1_p115_C PF04871.13 ORY33577.1 - 1.2 9.5 8.9 3.1 8.2 4.2 2.3 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region HSCB_C PF07743.13 ORY33577.1 - 1.5 9.3 6.9 1.5 9.4 1.8 2.7 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain Cep57_MT_bd PF06657.13 ORY33577.1 - 10 6.7 10.3 50 4.5 0.1 3.9 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Porphobil_deam PF01379.20 ORY33578.1 - 1.7e-77 259.6 0.0 2.1e-77 259.2 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 ORY33578.1 - 3.9e-16 59.2 0.1 1.2e-15 57.7 0.0 1.9 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain LPD29 PF18847.1 ORY33578.1 - 0.22 12.5 0.0 1.4 9.9 0.0 2.1 2 0 0 2 2 2 0 Large polyvalent protein associated domain 29 B-block_TFIIIC PF04182.12 ORY33579.1 - 1.8e-19 69.7 0.5 2e-18 66.3 0.1 2.9 3 0 0 3 3 3 1 B-block binding subunit of TFIIIC PHD PF00628.29 ORY33579.1 - 6.2e-09 35.6 9.3 6.2e-09 35.6 9.3 2.1 2 0 0 2 2 2 1 PHD-finger HTH_24 PF13412.6 ORY33579.1 - 0.00045 19.7 0.0 0.85 9.2 0.0 3.9 3 0 0 3 3 3 1 Winged helix-turn-helix DNA-binding MarR PF01047.22 ORY33579.1 - 0.038 13.9 3.6 4 7.4 0.0 4.9 5 0 0 5 5 5 0 MarR family MarR_2 PF12802.7 ORY33579.1 - 0.13 12.2 0.2 1.9 8.4 0.0 2.9 3 0 0 3 3 3 0 MarR family AIM3 PF17096.5 ORY33579.1 - 0.39 11.7 4.3 1.9 9.5 4.3 2.2 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 RNA_pol_Rpc34 PF05158.12 ORY33579.1 - 0.86 8.9 4.0 0.7 9.2 0.0 2.8 3 0 0 3 3 3 0 RNA polymerase Rpc34 subunit C1_2 PF03107.16 ORY33579.1 - 2.1 8.7 5.5 1.3 9.4 2.8 2.1 2 0 0 2 2 2 0 C1 domain zf-AN1 PF01428.16 ORY33580.1 - 2.1e-09 37.4 11.8 2.5e-09 37.2 11.8 1.1 1 0 0 1 1 1 1 AN1-like Zinc finger CN_hydrolase PF00795.22 ORY33581.1 - 2e-14 53.6 0.0 2.2e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ubiquitin PF00240.23 ORY33582.1 - 2.4e-15 56.1 0.0 2.5e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY33582.1 - 3.8e-07 29.8 0.0 4.1e-07 29.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 ORY33582.1 - 0.00014 21.8 0.1 0.26 11.4 0.0 2.0 1 1 1 2 2 2 2 Ubiquitin-like domain Phage_sheath_1N PF17481.2 ORY33582.1 - 0.0052 17.3 0.0 0.0056 17.2 0.0 1.0 1 0 0 1 1 1 1 Phage tail sheath protein beta-sandwich domain TUG-UBL1 PF11470.8 ORY33582.1 - 0.015 15.5 0.0 0.13 12.5 0.0 1.9 1 1 0 1 1 1 0 TUG ubiquitin-like domain TBK1_ULD PF18396.1 ORY33582.1 - 0.035 14.0 0.0 0.043 13.7 0.0 1.1 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain NAD_synthase PF02540.17 ORY33583.1 - 0.00068 18.8 0.0 0.00071 18.8 0.0 1.1 1 0 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.22 ORY33585.1 - 4.1e-37 127.9 0.0 5.8e-37 127.4 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 ORY33585.1 - 9.6e-16 57.6 0.0 1.6e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 NAD synthase zf-MYND PF01753.18 ORY33588.1 - 3.3e-12 46.3 12.2 9.4e-12 44.8 12.2 1.8 1 0 0 1 1 1 1 MYND finger SET PF00856.28 ORY33588.1 - 9e-09 35.9 0.1 1.3e-08 35.4 0.1 1.3 1 0 0 1 1 1 1 SET domain zf-ribbon_3 PF13248.6 ORY33588.1 - 0.2 11.1 0.0 0.2 11.1 0.0 3.2 4 0 0 4 4 4 0 zinc-ribbon domain zf-C6H2 PF15801.5 ORY33588.1 - 0.24 11.7 7.0 1.2 9.5 7.0 2.3 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PPR_2 PF13041.6 ORY33589.1 - 3.2e-09 36.8 1.2 3.7e-07 30.2 0.0 3.5 4 0 0 4 4 4 1 PPR repeat family PPR PF01535.20 ORY33589.1 - 0.00018 21.5 0.3 0.016 15.4 0.0 3.2 3 0 0 3 3 3 1 PPR repeat PPR_3 PF13812.6 ORY33589.1 - 0.00028 20.9 0.2 0.015 15.3 0.0 3.2 2 1 1 3 3 3 1 Pentatricopeptide repeat domain GcrA PF07750.11 ORY33589.1 - 0.00041 20.8 0.0 0.001 19.5 0.0 1.7 1 0 0 1 1 1 1 GcrA cell cycle regulator TAP_C PF03943.13 ORY33589.1 - 0.14 11.8 0.7 0.56 9.9 0.1 2.2 2 0 0 2 2 2 0 TAP C-terminal domain MFS_1 PF07690.16 ORY33590.1 - 9.3e-28 97.2 70.2 7.9e-23 80.9 32.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY33590.1 - 0.00029 19.8 30.5 0.00057 18.9 30.4 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter CDH-cyt PF16010.5 ORY33590.1 - 2.3 7.9 7.3 4.4 6.9 7.3 1.5 1 0 0 1 1 1 0 Cytochrome domain of cellobiose dehydrogenase Aconitase PF00330.20 ORY33592.1 - 4.9e-114 381.9 0.7 6e-113 378.3 0.7 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORY33592.1 - 3.9e-17 62.8 0.0 7.2e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 ORY33592.1 - 0.1 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Peptidase_M28 PF04389.17 ORY33593.1 - 2.1e-21 76.5 0.0 3.1e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ORY33593.1 - 1.9e-05 24.5 0.0 2.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 ORY33594.1 - 5.9e-20 71.8 0.0 7.8e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ORY33594.1 - 1.5e-05 24.8 0.0 3.8e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 PQQ_3 PF13570.6 ORY33595.1 - 1.1e-34 118.0 11.9 2.1e-06 28.0 0.0 9.6 10 0 0 10 10 10 6 PQQ-like domain PQQ_2 PF13360.6 ORY33595.1 - 3.4e-29 102.1 0.0 1.6e-16 60.6 0.0 3.0 1 1 2 3 3 3 3 PQQ-like domain PQQ PF01011.21 ORY33595.1 - 7.4e-29 98.3 9.0 3.7e-08 32.9 0.0 7.6 7 0 0 7 7 7 5 PQQ enzyme repeat WW PF00397.26 ORY33595.1 - 1 9.5 2.9 64 3.8 1.6 3.1 2 0 0 2 2 2 0 WW domain LSM PF01423.22 ORY33596.1 - 3.2e-18 65.2 0.1 4.4e-18 64.7 0.1 1.2 1 0 0 1 1 1 1 LSM domain GRIM-19 PF06212.12 ORY33597.1 - 2e-19 69.8 0.1 6.9e-18 64.9 0.0 2.1 2 0 0 2 2 2 2 GRIM-19 protein DUF1929 PF09118.11 ORY33598.1 - 9.7e-19 67.5 0.1 2e-18 66.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyoxal_oxid_N PF07250.11 ORY33598.1 - 8.9e-13 48.0 0.1 7e-12 45.1 0.0 2.4 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus Kelch_3 PF13415.6 ORY33598.1 - 2e-06 28.0 0.3 0.45 10.9 0.0 4.7 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY33598.1 - 0.00019 21.6 0.1 2 8.9 0.0 4.7 4 1 1 5 5 5 1 Kelch motif Kelch_4 PF13418.6 ORY33598.1 - 0.0028 17.6 1.6 9.5 6.3 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain DUF1929 PF09118.11 ORY33599.1 - 7.1e-17 61.5 0.1 1.5e-16 60.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyoxal_oxid_N PF07250.11 ORY33599.1 - 1.2e-14 54.1 0.0 7.6e-13 48.2 0.0 3.1 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus Kelch_6 PF13964.6 ORY33599.1 - 1.5e-06 28.2 0.1 0.15 12.4 0.0 4.7 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 ORY33599.1 - 0.0021 18.0 0.7 0.07 13.1 0.0 3.7 6 0 0 6 6 6 1 Kelch motif Kelch_1 PF01344.25 ORY33599.1 - 0.026 14.1 0.2 14 5.3 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Kelch_4 PF13418.6 ORY33599.1 - 0.087 12.9 0.7 8.3 6.5 0.0 3.8 3 0 0 3 3 3 0 Galactose oxidase, central domain Peptidase_M28 PF04389.17 ORY33600.1 - 5.7e-20 71.8 0.0 6.9e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ORY33600.1 - 2.4e-05 24.1 0.0 2.8e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 FA_desaturase PF00487.24 ORY33601.1 - 7.6e-32 111.1 19.7 8.8e-32 110.9 19.7 1.0 1 0 0 1 1 1 1 Fatty acid desaturase LSM14 PF12701.7 ORY33601.1 - 0.15 12.2 0.0 0.41 10.8 0.0 1.7 2 0 0 2 2 2 0 Scd6-like Sm domain Cyt-b5 PF00173.28 ORY33602.1 - 1.8e-11 44.0 0.0 2e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2873 PF11395.8 ORY33603.1 - 0.51 10.2 2.6 1 9.3 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2873) DUF599 PF04654.12 ORY33604.1 - 3.5e-14 52.7 0.3 4.5e-14 52.4 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF599 DUF624 PF04854.14 ORY33604.1 - 0.038 14.1 1.4 0.083 13.0 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF624 DUF4245 PF14030.6 ORY33604.1 - 0.076 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) DUF599 PF04654.12 ORY33605.1 - 2.1e-44 151.5 3.9 1e-43 149.2 3.9 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF599 SPC12 PF06645.13 ORY33605.1 - 0.69 10.0 5.6 7.7 6.7 0.4 2.6 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Sec1 PF00995.23 ORY33606.1 - 4.7e-118 395.9 6.4 5.4e-118 395.7 6.4 1.0 1 0 0 1 1 1 1 Sec1 family EF-hand_13 PF17958.1 ORY33607.1 - 2.2e-21 75.5 0.2 8.8e-21 73.5 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 ORY33607.1 - 1.4e-14 54.2 0.3 4.6e-13 49.4 0.0 3.6 3 1 0 3 3 2 1 EF-hand domain pair EF-hand_1 PF00036.32 ORY33607.1 - 6.2e-08 31.7 0.0 8.8e-05 21.8 0.0 3.7 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 ORY33607.1 - 4.9e-07 28.9 0.2 3.1e-06 26.4 0.0 2.5 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 ORY33607.1 - 1.3e-05 24.7 0.0 0.00052 19.7 0.0 3.3 4 0 0 4 4 2 1 EF-hand domain EF-hand_8 PF13833.6 ORY33607.1 - 0.023 14.5 0.6 0.37 10.7 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain pair Roughex PF06020.11 ORY33607.1 - 0.026 13.6 0.1 0.036 13.2 0.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein FAM176 PF14851.6 ORY33607.1 - 0.082 12.6 4.4 0.17 11.5 4.4 1.4 1 0 0 1 1 1 0 FAM176 family SPARC_Ca_bdg PF10591.9 ORY33607.1 - 0.095 13.0 2.7 0.58 10.5 0.0 3.1 4 0 0 4 4 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3464 PF11947.8 ORY33607.1 - 0.13 12.0 1.8 3.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 LAT PF15234.6 ORY33607.1 - 0.31 10.7 3.5 0.55 9.9 3.5 1.3 1 0 0 1 1 1 0 Linker for activation of T-cells Pox_Ag35 PF03286.14 ORY33607.1 - 0.51 10.1 5.2 0.97 9.2 5.2 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Astro_capsid_p PF12226.8 ORY33607.1 - 0.56 9.3 7.7 4.4 6.4 6.8 2.1 2 0 0 2 2 2 0 Turkey astrovirus capsid protein GCIP PF13324.6 ORY33607.1 - 1.4 8.5 5.5 5.7 6.5 0.8 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting CENP-B_dimeris PF09026.10 ORY33607.1 - 3.1 8.2 13.3 0.094 13.1 4.9 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 ORY33607.1 - 6.7 7.2 9.3 2.7 8.4 4.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.6 ORY33607.1 - 8.6 6.7 12.4 7 6.9 7.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Peptidase_S28 PF05577.12 ORY33609.1 - 3.5e-45 154.6 0.0 4.1e-45 154.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 ORY33609.1 - 0.0031 17.2 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY33609.1 - 0.032 13.7 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S28 PF05577.12 ORY33610.1 - 1.5e-63 215.1 3.3 2.1e-63 214.6 3.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 ORY33610.1 - 0.02 14.6 0.6 0.42 10.2 0.1 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY33610.1 - 0.026 14.0 0.4 0.074 12.5 0.1 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family IP_trans PF02121.18 ORY33610.1 - 0.1 12.1 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Phosphatidylinositol transfer protein LRR_8 PF13855.6 ORY33611.1 - 8.7e-13 47.8 11.5 1.2e-05 25.0 2.1 4.1 2 1 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 ORY33611.1 - 2.4e-10 40.5 7.7 0.011 16.1 0.0 4.0 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) F-box PF00646.33 ORY33611.1 - 2.2e-07 30.6 0.1 5.5e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.33 ORY33611.1 - 8.2e-07 28.7 12.3 8.2 7.4 0.0 7.6 7 1 0 7 7 7 2 Leucine Rich Repeat F-box-like PF12937.7 ORY33611.1 - 2.2e-05 24.3 0.1 6.3e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 ORY33611.1 - 0.053 13.6 2.8 23 5.4 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich repeat Dicty_REP PF05086.12 ORY33612.1 - 3.6 5.5 15.7 5 5.0 15.7 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Bmt2 PF11968.8 ORY33613.1 - 1.2e-66 224.7 0.0 1.4e-66 224.5 0.0 1.0 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_23 PF13489.6 ORY33613.1 - 4.5e-05 23.3 0.0 8.4e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Pox_D5 PF03288.16 ORY33613.1 - 0.023 15.2 0.1 0.041 14.4 0.1 1.4 1 0 0 1 1 1 0 Poxvirus D5 protein-like 7tm_3 PF00003.22 ORY33614.1 - 2.6e-15 56.8 25.2 4.6e-15 56.0 25.2 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 ORY33614.1 - 6.9e-12 45.1 0.1 1e-11 44.6 0.1 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Phage_holin_5_2 PF16079.5 ORY33614.1 - 0.64 10.4 6.8 0.39 11.1 1.2 2.9 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V ANF_receptor PF01094.28 ORY33615.1 - 4.7e-13 49.0 0.2 5.5e-13 48.7 0.2 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Glyco_transf_28 PF03033.20 ORY33615.1 - 0.052 13.6 0.0 0.057 13.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain PLAC8 PF04749.17 ORY33616.1 - 1.7e-15 57.8 13.9 2.1e-15 57.5 13.9 1.1 1 0 0 1 1 1 1 PLAC8 family Retrotran_gag_2 PF14223.6 ORY33617.1 - 0.00013 21.6 0.4 0.00051 19.7 0.1 2.0 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC_2 PF13696.6 ORY33617.1 - 0.001 18.9 3.4 0.001 18.9 3.4 1.7 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.17 ORY33617.1 - 0.0015 18.8 0.0 0.0035 17.6 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein eIF3g PF12353.8 ORY33617.1 - 0.01 16.2 0.1 0.029 14.8 0.1 1.8 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.6 ORY33617.1 - 0.013 15.4 1.6 0.024 14.6 1.6 1.3 1 0 0 1 1 1 0 Zinc knuckle Rep_fac_C PF08542.11 ORY33617.1 - 0.016 15.6 0.1 0.058 13.8 0.0 1.9 2 0 0 2 2 2 0 Replication factor C C-terminal domain FlaF PF07309.11 ORY33617.1 - 0.02 14.9 1.7 0.11 12.5 0.0 2.4 3 0 0 3 3 3 0 Flagellar protein FlaF Sulfatase PF00884.23 ORY33617.1 - 0.051 13.0 0.1 0.17 11.2 0.0 1.8 1 1 0 2 2 2 0 Sulfatase Rubredoxin_2 PF18073.1 ORY33617.1 - 0.38 10.5 5.3 0.59 9.9 5.3 1.3 1 0 0 1 1 1 0 Rubredoxin metal binding domain DUF4056 PF13265.6 ORY33618.1 - 0.17 11.2 0.0 0.34 10.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4056) Methyltransf_16 PF10294.9 ORY33619.1 - 2.7e-14 53.3 0.0 4.3e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 ORY33619.1 - 7.5e-06 25.8 0.1 1.7e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 ORY33619.1 - 4.3e-05 23.1 0.1 7.7e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ORY33619.1 - 9.3e-05 23.1 0.0 0.00019 22.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORY33619.1 - 0.0075 16.0 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 ORY33619.1 - 0.015 16.0 0.0 0.05 14.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 ORY33620.1 - 1.4e-12 47.7 1.8 2.9e-12 46.7 0.2 2.2 2 1 0 2 2 2 1 Lysine methyltransferase PrmA PF06325.13 ORY33620.1 - 1.3e-07 31.3 0.0 1.9e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 ORY33620.1 - 0.0001 23.0 0.0 0.00028 21.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY33620.1 - 0.00022 20.8 0.0 0.0004 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 ORY33620.1 - 0.0019 18.0 0.0 0.0034 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY33620.1 - 0.0044 16.8 0.0 0.0092 15.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY33620.1 - 0.008 16.9 0.0 0.049 14.4 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ORY33620.1 - 0.0097 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PCMT PF01135.19 ORY33620.1 - 0.037 13.8 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NNMT_PNMT_TEMT PF01234.17 ORY33620.1 - 0.045 12.9 0.0 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_11 PF08241.12 ORY33620.1 - 0.15 12.7 0.0 0.49 11.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 ORY33620.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain HET PF06985.11 ORY33621.1 - 4.2e-07 30.4 0.2 1.5e-05 25.4 0.0 2.3 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) Peptidase_M78 PF06114.13 ORY33621.1 - 0.12 12.3 0.1 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 IrrE N-terminal-like domain Branch PF02485.21 ORY33622.1 - 1.7e-29 103.1 0.0 2.5e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme GTP_CH_N PF12471.8 ORY33623.1 - 5.7e-90 300.3 0.0 8.6e-90 299.7 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 ORY33623.1 - 2.5e-15 56.4 0.0 5.3e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF4611 PF15387.6 ORY33623.1 - 0.19 12.0 1.0 0.62 10.3 0.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) Hormone_6 PF00236.18 ORY33624.1 - 0.17 11.9 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycoprotein hormone PAN_1 PF00024.26 ORY33625.1 - 5.1e-22 77.6 4.2 0.00014 21.7 1.3 4.1 3 1 1 4 4 4 4 PAN domain PAN_4 PF14295.6 ORY33625.1 - 8.2e-20 70.5 15.0 6e-07 29.3 0.6 4.6 4 1 0 4 4 4 4 PAN domain PAN_3 PF08277.12 ORY33625.1 - 5.4e-09 35.7 18.6 0.0013 18.5 0.7 4.1 4 0 0 4 4 4 4 PAN-like domain PAN_2 PF08276.11 ORY33625.1 - 0.005 16.9 18.6 0.67 10.1 0.1 4.2 4 0 0 4 4 4 3 PAN-like domain Lactamase_B PF00753.27 ORY33626.1 - 0.00037 20.6 0.0 0.00079 19.5 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY33626.1 - 0.00065 19.3 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DEAD PF00270.29 ORY33627.1 - 1.4e-44 152.0 0.0 2.5e-44 151.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY33627.1 - 1.4e-29 102.7 0.0 3.8e-28 98.0 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY33627.1 - 7.6e-07 29.3 0.0 5.5e-06 26.5 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY33627.1 - 0.046 14.0 0.4 0.41 10.9 0.4 2.4 1 1 0 1 1 1 0 AAA domain DUF4709 PF15821.5 ORY33630.1 - 0.00039 20.7 3.7 0.00047 20.4 1.2 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4709) Sec2p PF06428.11 ORY33630.1 - 0.0095 15.9 2.0 0.018 15.0 1.9 1.6 1 1 0 1 1 1 1 GDP/GTP exchange factor Sec2p ApbA_C PF08546.11 ORY33630.1 - 0.1 12.8 0.1 0.15 12.3 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal DNA_pol_B_thumb PF14791.6 ORY33630.1 - 0.16 12.1 0.2 0.38 10.9 0.2 1.6 1 0 0 1 1 1 0 DNA polymerase beta thumb Branch PF02485.21 ORY33632.1 - 1.8e-14 53.8 0.0 3e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme DNA_pol_B_exo1 PF03104.19 ORY33815.1 - 1e-25 90.6 0.0 1.5e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 ORY33815.1 - 2.2e-25 89.3 3.5 4.1e-12 45.6 0.1 3.1 1 1 2 3 3 3 3 DNA polymerase family B RNase_H_2 PF13482.6 ORY33815.1 - 0.00019 21.4 0.9 0.023 14.7 0.9 2.4 1 1 0 1 1 1 1 RNase_H superfamily RRM_1 PF00076.22 ORY33816.1 - 5.5e-14 51.7 0.1 2e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY33816.1 - 0.029 14.0 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TIM21 PF08294.11 ORY33816.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 TIM21 DNA_pol_B_exo1 PF03104.19 ORY33824.1 - 7.4e-26 91.1 0.1 1.8e-25 89.8 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 ORY33824.1 - 3.6e-24 85.3 6.9 5.5e-12 45.1 0.1 3.5 2 1 2 4 4 4 3 DNA polymerase family B zf-C4pol PF14260.6 ORY33824.1 - 3.9e-17 62.5 7.3 7.4e-17 61.6 7.3 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.6 ORY33824.1 - 0.0003 20.8 0.8 0.033 14.2 0.8 2.5 1 1 0 1 1 1 1 RNase_H superfamily RRM_1 PF00076.22 ORY33825.1 - 4.5e-15 55.2 0.0 5e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY33825.1 - 0.033 14.3 0.0 0.26 11.4 0.0 1.9 1 1 1 2 2 2 0 RNA recognition motif RRM_5 PF13893.6 ORY33825.1 - 0.046 13.3 0.0 0.052 13.2 0.0 1.0 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3885 PF13021.6 ORY33825.1 - 0.16 12.1 0.0 0.88 9.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) TIM21 PF08294.11 ORY33826.1 - 0.06 13.2 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 TIM21 DIMCO_N PF16844.5 ORY33827.1 - 0.06 13.7 0.1 1.8 9.0 0.0 2.1 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor, N-terminal Caskin-tail PF16632.5 ORY33828.1 - 0.048 14.1 0.1 0.069 13.6 0.1 1.2 1 0 0 1 1 1 0 C-terminal region of Caskin Helitron_like_N PF14214.6 ORY33832.1 - 3.5e-16 60.0 0.0 4.3e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF4368 PF14287.6 ORY33832.1 - 0.025 14.9 0.1 0.061 13.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4368) PIF1 PF05970.14 ORY33834.1 - 1.8e-08 34.0 0.0 1.9e-08 33.9 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 ORY33834.1 - 1.2e-07 31.7 0.0 1.2e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY33834.1 - 2.8e-06 27.7 0.2 4.2e-06 27.2 0.2 1.3 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 ORY33834.1 - 4.2e-06 25.9 0.0 4.7e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 ORY33834.1 - 0.00027 20.8 0.0 0.00034 20.5 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 ORY33834.1 - 0.00041 20.0 0.1 0.00071 19.3 0.0 1.5 1 1 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY33834.1 - 0.0028 18.1 0.0 0.003 17.9 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 ORY33834.1 - 0.0046 16.1 0.0 0.005 15.9 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein Viral_helicase1 PF01443.18 ORY33834.1 - 0.01 15.6 0.0 0.012 15.4 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF463 PF04317.12 ORY33834.1 - 0.013 14.5 0.2 0.014 14.3 0.2 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_22 PF13401.6 ORY33834.1 - 0.015 15.6 0.0 0.019 15.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORY33834.1 - 0.032 13.5 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.20 ORY33834.1 - 0.043 13.7 0.0 0.055 13.4 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase ResIII PF04851.15 ORY33834.1 - 0.054 13.5 0.0 0.064 13.3 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_24 PF13479.6 ORY33834.1 - 0.064 13.0 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 ORY33834.1 - 0.072 12.2 0.0 0.074 12.2 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_7 PF12775.7 ORY33834.1 - 0.082 12.4 0.1 0.15 11.5 0.1 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 ORY33834.1 - 0.084 11.8 0.0 0.093 11.6 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.6 ORY33834.1 - 0.089 13.3 0.1 0.16 12.5 0.0 1.5 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.15 ORY33834.1 - 0.093 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 NTPase cobW PF02492.19 ORY33834.1 - 0.12 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain IIGP PF05049.13 ORY33834.1 - 0.12 11.4 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_11 PF13086.6 ORY33834.1 - 0.15 11.9 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Herpes_Helicase PF02689.14 ORY33834.1 - 0.19 9.6 0.0 0.19 9.6 0.0 1.0 1 0 0 1 1 1 0 Helicase DUF2075 PF09848.9 ORY33834.1 - 0.25 10.6 0.0 0.3 10.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 ORY33835.1 - 5e-06 25.9 0.0 0.0017 17.6 0.0 2.1 1 1 0 1 1 1 1 PIF1-like helicase DUF5477 PF17571.2 ORY33840.1 - 0.07 13.3 1.1 0.07 13.3 1.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5477) RRM_1 PF00076.22 ORY33842.1 - 1.1e-19 70.0 0.0 2.7e-13 49.5 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4573 PF15140.6 ORY33842.1 - 2.3e-09 37.3 14.4 0.00018 21.4 12.8 3.0 1 1 0 2 2 2 2 Domain of unknown function (DUF4573) RRM_5 PF13893.6 ORY33842.1 - 0.061 12.9 0.0 0.19 11.3 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Amelogenin PF02948.15 ORY33842.1 - 1.9 9.1 13.4 0.37 11.4 6.5 3.0 3 1 1 4 4 4 0 Amelogenin Lem_TRP PF08262.11 ORY33843.1 - 1.5 9.0 4.4 1.6e+02 2.7 0.1 3.8 3 0 0 3 3 3 0 Leucophaea maderae tachykinin-related peptide Tad PF13400.6 ORY33843.1 - 6.4 7.2 9.8 21 5.5 1.5 2.7 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Herpes_BLRF2 PF05812.12 ORY33844.1 - 0.0081 16.3 0.4 0.017 15.3 0.4 1.6 1 1 0 1 1 1 1 Herpesvirus BLRF2 protein DivIC PF04977.15 ORY33844.1 - 0.07 12.9 1.1 0.15 11.8 1.1 1.5 1 0 0 1 1 1 0 Septum formation initiator ABC_tran_CTD PF16326.5 ORY33844.1 - 0.34 11.2 3.7 0.17 12.1 0.7 2.1 2 1 0 2 2 2 0 ABC transporter C-terminal domain ATP_bind_1 PF03029.17 ORY33847.1 - 1.6e-76 257.3 0.2 2.2e-76 256.8 0.2 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 ORY33847.1 - 1.3e-06 28.1 0.1 1.1e-05 25.1 0.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY33847.1 - 1.1e-05 25.5 0.0 0.00011 22.3 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY33847.1 - 0.00023 20.7 0.1 0.0019 17.7 0.0 2.4 3 0 0 3 3 3 1 Ferrous iron transport protein B MeaB PF03308.16 ORY33847.1 - 0.00051 19.1 0.1 0.32 9.9 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Ras PF00071.22 ORY33847.1 - 0.00062 19.4 0.0 0.0031 17.1 0.0 2.1 2 1 0 2 2 2 1 Ras family CLP1_P PF16575.5 ORY33847.1 - 0.0037 17.1 0.0 0.016 15.0 0.0 2.0 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CdiI_2 PF18593.1 ORY33847.1 - 0.011 16.4 0.2 0.053 14.2 0.1 2.2 2 0 0 2 2 2 0 CdiI immunity protein RsgA_GTPase PF03193.16 ORY33847.1 - 0.028 14.3 0.1 1.8 8.4 0.0 3.1 3 1 1 4 4 4 0 RsgA GTPase DUF87 PF01935.17 ORY33847.1 - 0.099 12.7 0.1 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_18 PF13238.6 ORY33847.1 - 0.26 11.8 2.2 13 6.4 0.0 3.3 2 1 0 3 3 3 0 AAA domain RRM_1 PF00076.22 ORY33848.1 - 1.4e-21 76.1 0.0 5.2e-10 39.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ead_Ea22 PF13935.6 ORY33848.1 - 0.00031 21.4 0.5 0.0005 20.7 0.5 1.4 1 0 0 1 1 1 1 Ead/Ea22-like protein Mod_r PF07200.13 ORY33848.1 - 0.012 15.8 4.4 0.22 11.6 1.2 3.1 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein AMP-binding PF00501.28 ORY33850.1 - 3.2e-68 230.2 0.0 4.7e-68 229.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 ORY33850.1 - 3.5e-68 229.6 0.0 5.1e-68 229.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 ORY33850.1 - 9.4e-15 54.7 0.1 3.7e-14 52.8 0.1 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site Condensation PF00668.20 ORY33850.1 - 1.2e-12 47.2 0.1 1.3e-11 43.9 0.1 2.0 1 1 0 1 1 1 1 Condensation domain 3Beta_HSD PF01073.19 ORY33850.1 - 7e-09 35.1 0.0 1.6e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY33850.1 - 2.2e-07 30.6 0.0 4.4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 ORY33850.1 - 9.7e-07 29.7 0.1 1.9e-05 25.6 0.0 2.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 ORY33850.1 - 0.016 15.1 0.0 0.5 10.2 0.0 2.5 1 1 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ORY33850.1 - 0.051 13.0 0.0 0.13 11.7 0.0 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase HMG-CoA_red PF00368.18 ORY33852.1 - 6.5e-95 318.2 0.1 1e-94 317.6 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase RRM_1 PF00076.22 ORY33853.1 - 1.9e-07 30.8 0.0 3.2e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY33853.1 - 0.0064 16.3 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif TFIIA PF03153.13 ORY33853.1 - 0.56 10.1 24.5 0.64 9.9 24.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Exonuc_VII_L PF02601.15 ORY33853.1 - 0.69 9.4 15.1 0.81 9.2 15.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TERB2 PF15101.6 ORY33853.1 - 5.1 7.1 9.6 7.4 6.6 9.6 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 PLAT PF01477.23 ORY33854.1 - 0.11 13.1 0.0 0.11 13.1 0.0 1.0 1 0 0 1 1 1 0 PLAT/LH2 domain RRM_1 PF00076.22 ORY33857.1 - 2.6e-07 30.3 0.0 5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4559 PF15112.6 ORY33857.1 - 0.036 13.8 11.8 0.069 12.8 11.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) BPL_N PF09825.9 ORY33857.1 - 4 6.4 14.9 5.4 6.0 14.9 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Pkinase PF00069.25 ORY33859.1 - 5.2e-57 193.2 0.0 5.9e-57 193.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY33859.1 - 3.7e-40 137.9 0.0 4.8e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY33859.1 - 6.9e-05 22.3 0.0 9.5e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY33859.1 - 0.0005 19.0 0.0 0.00082 18.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase SpoIIM PF01944.17 ORY33860.1 - 9.1 6.3 14.7 2.1 8.4 10.9 1.9 2 0 0 2 2 2 0 Stage II sporulation protein M Thioredoxin PF00085.20 ORY33862.1 - 1.3e-13 50.8 0.0 1.7e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY33862.1 - 0.011 16.2 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORY33862.1 - 0.035 14.4 0.0 0.13 12.6 0.0 1.8 1 1 1 2 2 2 0 Thioredoxin-like WD40 PF00400.32 ORY33863.1 - 1.8e-58 193.1 17.1 1.1e-09 38.7 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY33863.1 - 5.1e-16 58.8 0.0 0.0045 17.2 0.0 6.0 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY33863.1 - 1.3e-09 38.2 0.7 0.023 14.6 0.0 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ORY33863.1 - 1.4e-09 37.4 2.1 0.0038 16.2 0.1 5.5 2 1 4 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORY33863.1 - 0.0022 16.7 2.8 4.1 5.9 0.3 3.8 1 1 3 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY33863.1 - 0.0031 16.9 0.0 0.43 9.8 0.0 2.6 3 0 0 3 3 3 1 WD40-like domain Frtz PF11768.8 ORY33863.1 - 0.0068 14.8 0.0 0.023 13.0 0.0 1.7 1 1 1 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz DUF2603 PF10788.9 ORY33863.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) WW PF00397.26 ORY33865.1 - 8.5e-16 57.7 7.3 2.7e-09 36.9 0.3 2.5 2 0 0 2 2 2 2 WW domain ABC_tran_CTD PF16326.5 ORY33865.1 - 0.016 15.5 0.5 0.047 13.9 0.5 1.9 1 1 0 1 1 1 0 ABC transporter C-terminal domain PI3K_P85_iSH2 PF16454.5 ORY33865.1 - 0.031 13.9 3.5 0.054 13.1 3.2 1.5 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4407 PF14362.6 ORY33865.1 - 0.082 12.2 7.5 0.1 11.9 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Osmo_CC PF08946.10 ORY33865.1 - 3.3 8.0 8.2 1.6 9.0 0.3 2.8 3 0 0 3 3 3 0 Osmosensory transporter coiled coil DivIC PF04977.15 ORY33865.1 - 6.5 6.6 11.3 0.56 10.0 0.3 2.8 2 1 0 2 2 2 0 Septum formation initiator CALCOCO1 PF07888.11 ORY33866.1 - 2.3e-06 26.8 12.3 3.7e-06 26.1 12.3 1.5 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4482 PF14818.6 ORY33866.1 - 0.0072 17.2 6.8 0.022 15.6 6.8 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4482) DUF2508 PF10704.9 ORY33866.1 - 0.024 14.8 5.4 0.024 14.8 5.4 3.3 4 0 0 4 4 3 0 Protein of unknown function (DUF2508) TMCO5 PF14992.6 ORY33866.1 - 0.085 12.4 17.7 0.16 11.5 16.7 1.8 1 1 0 1 1 1 0 TMCO5 family Spc7 PF08317.11 ORY33866.1 - 0.091 11.6 13.9 0.16 10.9 13.9 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Fib_alpha PF08702.10 ORY33866.1 - 0.23 11.6 9.3 0.65 10.2 9.3 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ZapB PF06005.12 ORY33866.1 - 0.29 11.6 32.6 0.16 12.4 6.1 5.5 3 1 3 6 6 6 0 Cell division protein ZapB FlaC_arch PF05377.11 ORY33866.1 - 0.66 10.4 15.1 7.3 7.1 4.6 4.8 4 1 1 5 5 5 0 Flagella accessory protein C (FlaC) Mod_r PF07200.13 ORY33866.1 - 1.1 9.4 20.0 0.063 13.4 13.5 2.2 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein bZIP_2 PF07716.15 ORY33866.1 - 1.2 9.3 24.6 2.5 8.2 1.1 6.2 5 2 2 7 7 6 0 Basic region leucine zipper DUF1664 PF07889.12 ORY33866.1 - 1.4 8.9 6.0 1.9 8.5 4.5 2.1 2 1 0 2 2 1 0 Protein of unknown function (DUF1664) MRPL52 PF18699.1 ORY33866.1 - 1.8 8.8 8.6 1.3 9.3 5.9 2.2 1 1 1 2 2 2 0 Mitoribosomal protein mL52 TolA_bind_tri PF16331.5 ORY33866.1 - 2 8.5 13.0 5.4 7.2 0.2 4.0 3 1 1 4 4 4 0 TolA binding protein trimerisation DUF3450 PF11932.8 ORY33866.1 - 2.7 7.2 18.6 6 6.1 8.2 3.3 2 1 2 4 4 4 0 Protein of unknown function (DUF3450) Dzip-like_N PF13815.6 ORY33866.1 - 3.2 7.7 8.9 0.19 11.7 2.3 2.4 2 1 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Filament PF00038.21 ORY33866.1 - 3.5 7.1 22.3 2.5 7.6 19.0 2.2 1 1 1 2 2 2 0 Intermediate filament protein Fez1 PF06818.15 ORY33866.1 - 3.7 8.0 23.6 0.79 10.1 5.1 2.6 2 1 1 3 3 2 0 Fez1 TMPIT PF07851.13 ORY33866.1 - 3.7 6.7 8.7 4.5 6.4 7.6 1.6 1 1 0 1 1 1 0 TMPIT-like protein LMBR1 PF04791.16 ORY33866.1 - 4.1 6.2 4.8 5.7 5.7 4.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Lebercilin PF15619.6 ORY33866.1 - 5.5 6.6 27.2 0.043 13.5 17.4 2.3 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DivIC PF04977.15 ORY33866.1 - 7 6.5 19.5 2 8.2 6.4 4.4 2 1 2 4 4 4 0 Septum formation initiator Adap_comp_sub PF00928.21 ORY33867.1 - 8.6e-82 274.5 0.1 1.1e-81 274.1 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ORY33867.1 - 0.021 14.8 0.1 0.041 13.8 0.1 1.6 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Cu2_monooxygen PF01082.20 ORY33868.1 - 4e-31 108.0 0.3 6.2e-30 104.1 0.1 2.4 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 ORY33868.1 - 4.6e-26 91.2 0.0 8e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DOMON PF03351.17 ORY33868.1 - 1.3e-17 64.2 0.0 2.3e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 DOMON domain Acetyltransf_9 PF13527.7 ORY33868.1 - 4.9e-08 33.1 0.0 1.8e-07 31.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY33868.1 - 0.08 13.4 0.0 0.41 11.1 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PBP_like_2 PF12849.7 ORY33869.1 - 2.2e-13 50.5 1.3 4.7e-13 49.4 0.5 1.9 2 0 0 2 2 2 1 PBP superfamily domain MARVEL PF01284.23 ORY33869.1 - 0.62 10.1 10.2 5.8 6.9 2.6 3.4 4 0 0 4 4 4 0 Membrane-associating domain PAS PF00989.25 ORY33870.1 - 0.0059 16.6 0.0 0.43 10.6 0.0 2.2 1 1 1 2 2 2 2 PAS fold DUF3796 PF12676.7 ORY33871.1 - 0.038 14.4 0.8 0.052 14.0 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) PBP_like_2 PF12849.7 ORY33872.1 - 2.3e-09 37.3 0.1 5.4e-09 36.1 0.1 1.6 1 0 0 1 1 1 1 PBP superfamily domain DUF3611 PF12263.8 ORY33872.1 - 0.098 12.5 1.5 1.4 8.8 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) Ribosomal_S24e PF01282.19 ORY33873.1 - 0.034 14.1 0.0 0.041 13.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S24e FliD_N PF02465.18 ORY33876.1 - 0.15 12.8 1.9 0.48 11.2 0.0 2.5 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus YABBY PF04690.13 ORY33876.1 - 0.43 11.1 2.6 0.49 10.9 0.6 1.9 2 0 0 2 2 2 0 YABBY protein zf-CCHC PF00098.23 ORY33877.1 - 4.3e-07 29.7 3.9 7.8e-07 28.9 3.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 ORY33877.1 - 0.038 13.7 2.1 0.079 12.7 1.4 1.8 2 0 0 2 2 2 0 Zinc knuckle Ribosomal_S24e PF01282.19 ORY33878.1 - 0.034 14.1 0.0 0.041 13.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S24e Cu2_monooxygen PF01082.20 ORY33879.1 - 3e-32 111.6 0.2 5.7e-32 110.7 0.2 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 ORY33879.1 - 7.3e-23 80.8 0.0 1.1e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DOMON PF03351.17 ORY33879.1 - 8.1e-14 51.9 0.0 1.9e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 DOMON domain Cu2_monooxygen PF01082.20 ORY33880.1 - 4.5e-30 104.6 0.2 1e-29 103.4 0.2 1.6 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 ORY33880.1 - 8.1e-29 100.2 0.2 1.4e-28 99.4 0.2 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Glyco_transf_18 PF15024.6 ORY33881.1 - 0.12 11.0 0.0 0.12 10.9 0.0 1.0 1 0 0 1 1 1 0 Glycosyltransferase family 18 Pkinase PF00069.25 ORY33882.1 - 1.5e-44 152.3 0.0 1.9e-44 152.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY33882.1 - 2.1e-15 56.7 0.0 4.5e-15 55.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 ORY33882.1 - 1.3e-06 27.9 0.0 2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY33882.1 - 0.00021 20.2 0.0 0.00028 19.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 ORY33882.1 - 0.0011 18.6 0.1 0.0015 18.2 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 ORY33882.1 - 0.032 14.2 0.0 0.12 12.3 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family End3 PF12761.7 ORY33883.1 - 0.0059 16.8 5.5 0.013 15.7 5.5 1.5 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 PSII_BNR PF14870.6 ORY33883.1 - 0.06 12.6 0.1 4.6 6.4 0.0 2.5 2 0 0 2 2 2 0 Photosynthesis system II assembly factor YCF48 DUF5320 PF17253.2 ORY33883.1 - 0.06 14.4 0.0 0.06 14.4 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5320) ProSAAS PF07259.12 ORY33883.1 - 0.97 9.4 4.3 1.6 8.7 4.3 1.3 1 0 0 1 1 1 0 ProSAAS precursor FapA PF03961.13 ORY33883.1 - 1.3 7.6 3.4 1.7 7.2 3.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A RRM_1 PF00076.22 ORY33884.1 - 2.9e-14 52.6 0.2 4.2e-14 52.1 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORY33884.1 - 2.4e-05 24.3 0.1 3.3e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 RNA binding motif AMP-binding PF00501.28 ORY33885.1 - 2.9e-99 332.5 0.0 3.7e-99 332.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY33885.1 - 0.0003 21.7 0.0 0.00071 20.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CRM1_repeat PF18777.1 ORY33886.1 - 0.078 12.5 0.2 0.17 11.4 0.2 1.6 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat LRR_8 PF13855.6 ORY33888.1 - 3e-19 68.5 19.7 3.8e-08 33.0 5.5 4.3 1 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 ORY33888.1 - 5.7e-17 61.5 14.2 5.5e-06 26.6 1.6 4.8 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY33888.1 - 3e-09 36.2 18.8 0.17 12.6 0.1 7.6 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 ORY33888.1 - 0.00045 20.1 11.0 4.7 7.5 0.1 5.4 5 0 0 5 5 5 3 Leucine Rich repeat F-box PF00646.33 ORY33888.1 - 0.0093 15.8 0.1 0.027 14.3 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY33888.1 - 0.063 13.2 0.4 0.15 12.0 0.4 1.7 1 0 0 1 1 1 0 F-box-like Peptidase_M20 PF01546.28 ORY33889.1 - 9.1e-35 120.2 11.6 1.9e-34 119.2 11.6 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY33889.1 - 0.0005 20.0 0.0 0.0012 18.7 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ORY33889.1 - 0.0057 16.4 0.0 0.1 12.3 0.0 2.5 2 1 0 2 2 2 1 Peptidase family M28 TMEM141 PF15110.6 ORY33890.1 - 0.017 15.7 0.3 0.023 15.3 0.3 1.2 1 0 0 1 1 1 0 TMEM141 protein family DUF5389 PF17364.2 ORY33890.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5389) zf-CCHC_2 PF13696.6 ORY33891.1 - 0.00089 19.0 15.0 0.001 18.8 5.1 2.4 2 0 0 2 2 2 2 Zinc knuckle SAYSvFN PF10260.9 ORY33895.1 - 0.043 13.7 1.2 0.043 13.7 1.2 2.2 2 1 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) Peptidase_M24 PF00557.24 ORY33899.1 - 6.2e-58 195.9 0.2 8.5e-58 195.5 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 ORY33899.1 - 1.9e-35 121.2 0.0 3.6e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Ost5 PF05251.12 ORY33900.1 - 0.039 14.2 0.2 0.039 14.2 0.2 1.6 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 Macscav_rec PF03523.13 ORY33902.1 - 0.28 11.1 1.9 0.45 10.5 0.7 2.0 2 0 0 2 2 2 0 Macrophage scavenger receptor ADH_zinc_N PF00107.26 ORY33904.1 - 1.7e-26 92.7 0.1 1.3e-12 47.8 0.0 2.7 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY33904.1 - 1.1e-10 41.3 0.9 0.00041 20.2 0.1 2.5 2 0 0 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ORY33904.1 - 1.8e-07 32.3 0.3 0.013 16.5 0.1 3.4 2 2 0 2 2 2 2 Zinc-binding dehydrogenase DUF4350 PF14258.6 ORY33904.1 - 0.058 13.8 0.0 13 6.3 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) YAcAr PF10686.9 ORY33904.1 - 0.15 12.1 0.0 21 5.2 0.0 2.6 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family ADH_N_2 PF16884.5 ORY33904.1 - 0.18 11.7 0.1 1.1 9.2 0.0 2.3 2 1 0 2 2 2 0 N-terminal domain of oxidoreductase Cpn10 PF00166.21 ORY33904.1 - 0.37 10.9 1.5 14 5.9 0.1 2.6 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit DUF829 PF05705.14 ORY33909.1 - 6.5e-25 88.4 0.1 2.1e-18 67.1 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF829) YesK PF14150.6 ORY33910.1 - 0.052 13.8 1.5 0.052 13.8 1.5 3.0 2 1 0 3 3 3 0 YesK-like protein GRAB PF10375.9 ORY33910.1 - 0.1 12.5 2.5 0.29 11.1 2.5 1.8 1 0 0 1 1 1 0 GRIP-related Arf-binding domain ABC_membrane PF00664.23 ORY33913.1 - 4.5e-109 364.3 34.4 3.4e-56 190.9 9.7 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY33913.1 - 2.4e-69 232.1 0.0 2.4e-35 122.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY33913.1 - 7.9e-17 61.4 5.5 1.2e-06 28.2 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORY33913.1 - 2.6e-07 31.0 0.1 0.01 16.1 0.0 3.2 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ORY33913.1 - 3.1e-07 30.0 0.5 0.012 15.3 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY33913.1 - 4.2e-07 30.5 1.8 0.023 15.1 0.1 3.2 2 1 1 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORY33913.1 - 1.4e-06 28.3 0.0 0.018 14.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 ORY33913.1 - 2.8e-06 26.4 0.3 0.081 11.7 0.2 3.4 3 0 0 3 3 3 2 Predicted ATPase of the ABC class G-alpha PF00503.20 ORY33913.1 - 7.7e-06 25.3 0.0 0.024 13.8 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit AAA_7 PF12775.7 ORY33913.1 - 5.4e-05 22.8 0.3 0.28 10.7 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 ORY33913.1 - 7.4e-05 22.1 0.1 0.028 13.7 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin AAA_15 PF13175.6 ORY33913.1 - 0.0001 22.2 0.0 0.04 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 ORY33913.1 - 0.00034 20.4 0.2 0.16 11.7 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 ORY33913.1 - 0.00035 20.5 0.3 0.86 9.3 0.0 3.7 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 ORY33913.1 - 0.00093 19.6 0.5 5.9 7.3 0.2 3.7 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 ORY33913.1 - 0.00096 18.4 1.0 0.8 8.8 0.2 2.3 2 0 0 2 2 2 2 NB-ARC domain AAA_24 PF13479.6 ORY33913.1 - 0.001 18.8 0.0 1.4 8.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 ORY33913.1 - 0.0013 19.2 0.3 2.5 8.5 0.0 2.8 3 0 0 3 3 2 1 AAA domain PRK PF00485.18 ORY33913.1 - 0.002 17.9 0.6 1.2 8.8 0.0 2.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 ORY33913.1 - 0.0021 18.1 0.1 3.7 7.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 ORY33913.1 - 0.0052 17.3 0.4 4.1 8.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 ORY33913.1 - 0.0068 16.1 0.8 3.1 7.4 0.1 2.8 3 1 0 3 3 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 ORY33913.1 - 0.0073 16.3 0.2 5.3 7.0 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Gtr1_RagA PF04670.12 ORY33913.1 - 0.0077 15.6 0.6 6 6.1 0.0 3.3 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region SbcCD_C PF13558.6 ORY33913.1 - 0.011 16.0 4.6 2.8 8.3 0.9 3.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 ORY33913.1 - 0.012 16.0 0.1 7.4 7.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 ORY33913.1 - 0.013 15.1 0.0 4.9 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ORY33913.1 - 0.016 15.4 0.2 5.1 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ORY33913.1 - 0.016 15.4 0.1 7.2 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 ORY33913.1 - 0.019 15.4 0.7 5.4 7.4 0.0 3.0 3 0 0 3 3 2 0 AAA domain MeaB PF03308.16 ORY33913.1 - 0.021 13.8 0.1 3.5 6.5 0.0 2.9 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ploopntkinase3 PF18751.1 ORY33913.1 - 0.021 14.7 0.4 1.6 8.6 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Rad17 PF03215.15 ORY33913.1 - 0.032 14.2 0.0 5.6 6.9 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain APS_kinase PF01583.20 ORY33913.1 - 0.036 14.0 0.1 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase DLIC PF05783.11 ORY33913.1 - 0.064 12.1 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) NACHT PF05729.12 ORY33913.1 - 0.075 12.9 1.0 2.5 8.0 0.1 2.6 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.13 ORY33913.1 - 0.087 12.0 0.0 12 4.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF87 PF01935.17 ORY33913.1 - 0.088 12.9 0.4 1.4 9.0 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Viral_helicase1 PF01443.18 ORY33913.1 - 0.088 12.5 0.0 3.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Roc PF08477.13 ORY33913.1 - 0.092 13.0 0.2 9.9 6.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase F-box PF00646.33 ORY33914.1 - 6.1e-06 26.0 0.0 1.5e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain Ank_2 PF12796.7 ORY33914.1 - 2.2e-05 25.0 0.4 0.00014 22.3 0.3 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) F-box-like PF12937.7 ORY33914.1 - 0.00011 22.0 0.0 0.00028 20.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like Ank_5 PF13857.6 ORY33914.1 - 0.00019 21.7 0.4 0.35 11.2 0.2 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PRANC PF09372.10 ORY33914.1 - 0.001 19.4 0.1 1.1 9.6 0.0 3.2 3 0 0 3 3 3 2 PRANC domain Ank_3 PF13606.6 ORY33914.1 - 0.0011 19.3 0.1 20 6.2 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 ORY33914.1 - 0.043 14.4 0.5 1.7 9.3 0.3 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) RasGEF PF00617.19 ORY33915.1 - 1.1e-26 94.1 0.2 2.6e-26 92.9 0.2 1.6 1 0 0 1 1 1 1 RasGEF domain Sec1 PF00995.23 ORY33918.1 - 3.5e-07 29.8 1.6 0.0026 17.1 0.2 2.3 2 1 0 2 2 2 2 Sec1 family HTH_5 PF01022.20 ORY33919.1 - 0.14 12.1 0.0 5.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family Ribosomal_S8e PF01201.22 ORY33919.1 - 0.41 10.8 2.0 3 8.0 0.5 2.1 2 0 0 2 2 2 0 Ribosomal protein S8e MerR-DNA-bind PF09278.11 ORY33919.1 - 0.66 10.6 4.9 1.4 9.5 4.9 1.5 1 0 0 1 1 1 0 MerR, DNA binding WD40 PF00400.32 ORY33920.1 - 4.3e-128 413.5 60.9 2e-11 44.3 0.6 12.1 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY33920.1 - 8.1e-46 154.3 17.6 0.0029 17.9 0.0 12.0 1 1 11 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY33920.1 - 2.8e-24 85.7 19.2 0.047 12.3 0.0 11.7 1 1 11 12 12 12 10 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORY33920.1 - 4.9e-19 68.4 19.8 1.3 7.9 0.2 11.8 1 1 9 10 10 10 9 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORY33920.1 - 4.5e-17 62.6 3.8 0.00016 21.6 0.1 4.7 1 1 4 5 5 5 4 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY33920.1 - 7.7e-16 58.3 0.2 0.35 10.2 0.0 8.3 2 2 4 8 8 8 5 WD40-like domain PD40 PF07676.12 ORY33920.1 - 5.9e-09 35.6 9.1 37 4.4 0.0 11.5 12 0 0 12 12 12 0 WD40-like Beta Propeller Repeat HARP PF07443.13 ORY33920.1 - 2.2e-07 30.4 0.0 4.2 7.1 0.0 7.6 11 0 0 11 11 11 2 HepA-related protein (HARP) Plavaka PF18759.1 ORY33920.1 - 6.6e-05 22.3 0.0 0.27 10.4 0.0 3.2 3 1 0 3 3 3 2 Plavaka transposase FLgD_tudor PF13861.6 ORY33920.1 - 0.014 15.6 0.1 2 8.7 0.0 4.7 4 1 0 4 4 4 0 FlgD Tudor-like domain 120_Rick_ant PF12574.8 ORY33920.1 - 4.3 6.5 8.6 10 5.2 0.2 3.9 2 2 2 4 4 4 0 120 KDa Rickettsia surface antigen DUF3450 PF11932.8 ORY33921.1 - 0.00036 19.9 1.5 0.00044 19.6 1.2 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) Nsp1_C PF05064.13 ORY33921.1 - 0.001 18.8 1.2 0.0011 18.7 1.2 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region ZapB PF06005.12 ORY33921.1 - 0.0018 18.7 5.1 0.0025 18.2 5.1 1.3 1 1 0 1 1 1 1 Cell division protein ZapB BLOC1_2 PF10046.9 ORY33921.1 - 0.0021 18.3 1.1 0.0027 17.9 1.1 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 ORY33921.1 - 0.0031 17.4 0.9 0.0035 17.2 0.9 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 BST2 PF16716.5 ORY33921.1 - 0.0038 17.8 2.3 0.0049 17.4 2.3 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 GAS PF13851.6 ORY33921.1 - 0.0039 16.6 2.9 0.0044 16.4 2.9 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 ORY33921.1 - 0.017 15.1 2.0 0.017 15.1 2.0 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Cluap1 PF10234.9 ORY33921.1 - 0.018 14.4 1.5 0.019 14.4 1.5 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Tropomyosin_1 PF12718.7 ORY33921.1 - 0.024 14.8 2.5 0.036 14.2 2.5 1.4 1 1 0 1 1 1 0 Tropomyosin like YabA PF06156.13 ORY33921.1 - 0.026 15.1 1.3 0.031 14.9 1.3 1.2 1 0 0 1 1 1 0 Initiation control protein YabA HlyD_D23 PF16576.5 ORY33921.1 - 0.028 13.6 1.0 0.03 13.5 1.0 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Herpes_UL6 PF01763.16 ORY33921.1 - 0.028 12.9 1.7 0.029 12.9 1.7 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like BSP PF04450.12 ORY33921.1 - 0.034 14.0 0.0 0.053 13.3 0.0 1.3 1 1 0 1 1 1 0 Peptidase of plants and bacteria Rab_bind PF16704.5 ORY33921.1 - 0.035 14.1 0.3 2.8 8.1 0.1 2.3 1 1 1 2 2 2 0 Rab binding domain DUF948 PF06103.11 ORY33921.1 - 0.041 14.1 0.5 0.058 13.7 0.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 ORY33921.1 - 0.042 14.4 2.8 0.057 14.0 2.8 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 ORY33921.1 - 0.12 13.0 4.7 0.33 11.6 4.7 1.8 1 1 0 1 1 1 0 SlyX Cep57_MT_bd PF06657.13 ORY33921.1 - 0.13 12.7 3.5 1.7 9.2 0.8 2.2 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 XhlA PF10779.9 ORY33921.1 - 0.14 12.3 2.3 0.29 11.4 2.3 1.5 1 0 0 1 1 1 0 Haemolysin XhlA Fib_alpha PF08702.10 ORY33921.1 - 0.15 12.2 3.3 0.49 10.6 3.2 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 ORY33921.1 - 0.25 11.8 2.6 1.1 9.8 2.9 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 ORY33921.1 - 0.62 9.9 5.3 6.3 6.7 0.4 2.0 1 1 1 2 2 2 0 Septum formation initiator Neural_ProG_Cyt PF06567.11 ORY33923.1 - 4.9e-08 33.2 2.3 2.9 8.1 0.0 4.8 1 1 4 5 5 5 3 Neural chondroitin sulphate proteoglycan cytoplasmic domain MRP-S24 PF14955.6 ORY33923.1 - 5.1e-07 29.7 0.0 16 5.5 0.0 4.9 1 1 4 5 5 5 1 Mitochondrial ribosome subunit S24 ARTD15_N PF18084.1 ORY33923.1 - 6.7e-07 29.5 1.8 7.8 6.8 0.0 4.4 1 1 3 4 4 4 4 ARTD15 N-terminal domain PAP2_3 PF14378.6 ORY33923.1 - 7.6e-05 22.5 2.9 14 5.3 0.0 4.1 1 1 3 4 4 4 1 PAP2 superfamily Bravo_FIGEY PF13882.6 ORY33923.1 - 0.0007 20.9 0.3 21 6.5 0.0 3.7 1 1 3 4 4 4 0 Bravo-like intracellular region Lantibiotic_a PF14867.6 ORY33923.1 - 0.00082 19.1 0.0 1.3e+02 2.4 0.0 5.0 5 0 0 5 5 5 0 Lantibiotic alpha Proteasom_PSMB PF10508.9 ORY33923.1 - 0.0036 15.9 0.0 39 2.6 0.0 4.3 5 0 0 5 5 5 0 Proteasome non-ATPase 26S subunit DUF1798 PF08807.10 ORY33923.1 - 0.0093 16.1 0.0 57 3.9 0.0 4.1 1 1 4 5 5 5 0 Bacterial domain of unknown function (DUF1798) DUF2278 PF10042.9 ORY33923.1 - 0.015 15.3 0.3 34 4.4 0.0 3.5 1 1 3 4 4 4 0 Uncharacterized conserved protein (DUF2278) DUF3417 PF11897.8 ORY33923.1 - 0.07 13.6 0.3 40 4.7 0.0 2.8 1 1 3 4 4 4 0 Protein of unknown function (DUF3417) Diacid_rec PF05651.13 ORY33923.1 - 0.094 12.4 0.2 97 2.6 0.0 4.2 5 0 0 5 5 5 0 Putative sugar diacid recognition OPT PF03169.15 ORY34128.1 - 4.7e-123 412.0 51.3 5.5e-123 411.8 51.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3431 PF11913.8 ORY34129.1 - 1.5e-06 28.2 0.1 2.1e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Rft-1 PF04506.13 ORY34131.1 - 2.6e-11 43.0 3.5 2.9e-11 42.8 3.5 1.0 1 0 0 1 1 1 1 Rft protein TPR_2 PF07719.17 ORY34133.1 - 4.6e-18 63.8 9.4 0.00044 20.2 0.0 7.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORY34133.1 - 2.8e-13 49.3 7.2 0.00072 19.2 0.6 6.1 4 1 2 6 6 6 4 TPR repeat TPR_1 PF00515.28 ORY34133.1 - 4.3e-12 45.3 14.6 0.00015 21.4 0.0 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat zf-MYND PF01753.18 ORY34133.1 - 4.6e-09 36.2 10.1 4.6e-09 36.2 10.1 2.4 2 0 0 2 2 2 1 MYND finger TPR_8 PF13181.6 ORY34133.1 - 5.1e-09 35.6 8.5 0.04 14.1 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY34133.1 - 4.7e-08 33.1 0.5 0.012 15.8 0.0 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY34133.1 - 1.8e-06 27.9 2.9 0.16 12.4 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY34133.1 - 3e-05 24.6 1.0 1.8 9.2 0.0 4.3 3 1 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY34133.1 - 0.0001 22.4 9.1 0.0099 16.1 0.8 4.8 2 2 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 ORY34133.1 - 0.00016 22.2 3.7 6 8.0 0.0 6.4 3 2 4 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY34133.1 - 0.0019 18.7 7.5 0.85 10.2 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY34133.1 - 0.012 15.9 2.8 5.1 7.5 0.1 4.3 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY34133.1 - 0.15 11.4 0.1 0.76 9.1 0.0 2.1 2 0 0 2 2 2 0 MalT-like TPR region TPR_6 PF13174.6 ORY34133.1 - 0.31 11.8 3.7 32 5.4 0.2 4.2 3 0 0 3 3 2 0 Tetratricopeptide repeat gag-asp_proteas PF13975.6 ORY34134.1 - 0.0012 19.4 0.0 0.0034 17.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 ORY34134.1 - 0.0012 19.4 0.1 0.006 17.2 0.0 2.2 2 0 0 2 2 2 1 Aspartyl protease DDE_Tnp_4 PF13359.6 ORY34188.1 - 6.4e-08 32.4 0.0 9.8e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Hyccin PF09790.9 ORY34188.1 - 0.16 11.0 0.0 0.34 9.9 0.0 1.5 1 1 0 1 1 1 0 Hyccin Galactosyl_T PF01762.21 ORY34190.1 - 9.2e-10 38.7 0.2 4.3e-08 33.2 0.1 2.7 2 1 1 3 3 3 1 Galactosyltransferase Fringe PF02434.16 ORY34190.1 - 0.012 15.1 0.0 0.14 11.6 0.0 2.1 2 0 0 2 2 2 0 Fringe-like Glyco_transf_28 PF03033.20 ORY34191.1 - 1.1e-11 45.0 0.0 2.2e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 ORY34191.1 - 3.4e-05 23.9 0.0 5.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_28 PF03033.20 ORY34192.1 - 4.9e-11 42.8 0.0 7.9e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 ORY34192.1 - 0.00021 21.3 0.0 0.00036 20.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Cys_Met_Meta_PP PF01053.20 ORY34193.1 - 2.5e-13 49.3 0.8 1.5e-12 46.8 1.3 2.0 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Fungal_trans PF04082.18 ORY34193.1 - 0.0014 17.7 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3015 PF11220.8 ORY34398.1 - 0.0076 16.1 1.2 0.018 14.9 1.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3015) TMPIT PF07851.13 ORY34398.1 - 2.3 7.4 5.7 3.5 6.8 5.7 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF2203 PF09969.9 ORY34398.1 - 6.9 7.4 7.5 5.2 7.8 5.7 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DCX PF03607.17 ORY34400.1 - 3.7e-31 107.0 0.5 1.7e-13 50.4 0.0 3.4 3 0 0 3 3 3 3 Doublecortin KHA PF11834.8 ORY34400.1 - 0.067 13.3 0.0 19 5.4 0.0 2.7 2 0 0 2 2 2 0 KHA, dimerisation domain of potassium ion channel Sel1 PF08238.12 ORY34401.1 - 4.8e-28 97.0 7.9 3.9e-09 36.9 0.0 4.4 4 0 0 4 4 4 4 Sel1 repeat SNAP PF14938.6 ORY34401.1 - 0.0024 17.3 0.7 0.0024 17.3 0.7 1.5 2 0 0 2 2 2 1 Soluble NSF attachment protein, SNAP MIT PF04212.18 ORY34401.1 - 0.022 14.8 5.7 4.3 7.5 0.1 3.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 ORY34401.1 - 0.027 15.1 6.3 0.39 11.4 0.3 3.5 2 2 1 3 3 3 0 Tetratricopeptide repeat AmpE PF17113.5 ORY34401.1 - 0.1 11.9 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Regulatory signalling modulator protein AmpE TPR_7 PF13176.6 ORY34401.1 - 0.54 10.4 4.5 4.1 7.7 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY34401.1 - 0.55 10.6 4.4 0.45 10.8 0.9 2.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY34401.1 - 2 8.8 15.6 4.9 7.5 0.2 5.0 5 1 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.25 ORY34402.1 - 2.6e-21 76.2 0.0 3.1e-21 75.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY34402.1 - 1.1e-16 60.9 0.0 1.3e-16 60.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY34402.1 - 0.033 14.1 0.2 0.059 13.3 0.2 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Zn_clus PF00172.18 ORY34403.1 - 9.4e-09 35.3 22.5 7.1e-05 22.8 7.9 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 ORY34404.1 - 1.5e-29 103.1 0.0 4.8e-29 101.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY34404.1 - 4.9e-14 52.2 0.0 6.7e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY34404.1 - 0.0049 16.2 0.0 0.0077 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY34404.1 - 0.029 13.2 0.0 0.037 12.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF475 PF04332.15 ORY34404.1 - 0.079 12.7 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF475) MinE PF03776.14 ORY34407.1 - 0.07 13.1 0.0 0.078 13.0 0.0 1.1 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE PDZ_1 PF12812.7 ORY34408.1 - 0.013 15.5 0.0 0.015 15.3 0.0 1.1 1 0 0 1 1 1 0 PDZ-like domain Glyco_transf_24 PF18404.1 ORY34412.1 - 1e-146 487.4 1.0 1.4e-146 487.0 1.0 1.1 1 0 0 1 1 1 1 Glucosyltransferase 24 UDP-g_GGTase PF06427.11 ORY34412.1 - 5e-38 129.6 0.0 8.8e-38 128.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 ORY34412.1 - 2.2e-06 27.4 0.0 3.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Pkinase PF00069.25 ORY34413.1 - 2.3e-28 99.3 0.1 3.8e-23 82.2 0.0 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY34413.1 - 1e-10 41.3 0.2 1e-09 38.0 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY34413.1 - 0.053 12.3 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 ORY34413.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NTR PF01759.21 ORY34418.1 - 0.16 11.8 0.8 0.42 10.4 0.8 1.7 1 0 0 1 1 1 0 UNC-6/NTR/C345C module Glyco_transf_24 PF18404.1 ORY34420.1 - 1.3e-147 490.4 1.0 1.7e-147 490.0 1.0 1.1 1 0 0 1 1 1 1 Glucosyltransferase 24 UDP-g_GGTase PF06427.11 ORY34420.1 - 4.5e-38 129.7 0.0 7.7e-38 129.0 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 ORY34420.1 - 8.9e-07 28.7 0.0 1.5e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Ste5_C PF12194.8 ORY34423.1 - 0.024 14.6 0.5 0.9 9.5 0.5 2.2 1 1 0 1 1 1 0 Protein kinase Fus3-binding zf-C3HC4_2 PF13923.6 ORY34455.1 - 0.15 11.9 6.7 0.24 11.3 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_18 PF00704.28 ORY34457.1 - 1.2e-14 54.7 0.0 2e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PBP_like_2 PF12849.7 ORY34460.1 - 0.00059 19.6 0.1 0.0007 19.4 0.1 1.1 1 0 0 1 1 1 1 PBP superfamily domain DEAD PF00270.29 ORY34462.1 - 3e-25 89.0 0.8 5.3e-24 84.9 0.4 2.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY34462.1 - 7.1e-25 87.5 0.0 6.6e-24 84.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY34462.1 - 4.2e-05 23.6 0.1 0.018 15.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDC45 PF02724.14 ORY34462.1 - 0.0066 14.8 6.9 0.011 14.1 6.9 1.3 1 0 0 1 1 1 1 CDC45-like protein Presenilin PF01080.17 ORY34462.1 - 0.021 13.6 3.6 0.033 13.0 3.6 1.2 1 0 0 1 1 1 0 Presenilin Mpp10 PF04006.12 ORY34462.1 - 0.029 12.9 17.4 0.55 8.6 15.0 2.1 2 0 0 2 2 2 0 Mpp10 protein RNA_pol_Rpc4 PF05132.14 ORY34462.1 - 0.032 14.7 4.5 0.062 13.7 4.5 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Zip PF02535.22 ORY34462.1 - 0.046 12.9 1.1 0.069 12.4 1.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Merozoite_SPAM PF07133.11 ORY34462.1 - 0.048 13.6 17.7 0.11 12.5 17.7 1.5 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) LRIF1 PF15741.5 ORY34462.1 - 0.057 12.0 2.5 0.09 11.3 2.5 1.2 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 RR_TM4-6 PF06459.12 ORY34462.1 - 0.066 13.0 7.2 0.12 12.2 7.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DnaI_N PF07319.11 ORY34462.1 - 0.13 13.0 1.7 3.2 8.5 0.3 2.6 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus CobT PF06213.12 ORY34462.1 - 0.17 11.2 13.3 0.31 10.4 13.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF913 PF06025.12 ORY34462.1 - 0.19 10.6 2.4 0.36 9.8 2.4 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) EOS1 PF12326.8 ORY34462.1 - 0.27 11.1 0.5 0.48 10.3 0.5 1.3 1 0 0 1 1 1 0 N-glycosylation protein DUF2457 PF10446.9 ORY34462.1 - 0.3 10.2 19.0 0.47 9.5 19.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CPSF100_C PF13299.6 ORY34462.1 - 0.46 10.6 8.9 2.5 8.3 6.2 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Nop14 PF04147.12 ORY34462.1 - 0.47 8.6 15.2 0.72 8.0 15.2 1.2 1 0 0 1 1 1 0 Nop14-like family GAGA_bind PF06217.12 ORY34462.1 - 0.78 10.0 4.7 0.27 11.5 1.1 1.8 2 0 0 2 2 2 0 GAGA binding protein-like family RNA_polI_A34 PF08208.11 ORY34462.1 - 1.6 8.8 17.2 3.9 7.5 17.2 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DNA_pol_phi PF04931.13 ORY34462.1 - 3.3 5.7 13.2 5.1 5.1 13.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 ORY34462.1 - 3.7 7.2 7.9 7.7 6.2 7.9 1.5 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.16 ORY34462.1 - 5.5 6.1 9.0 8.6 5.5 9.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Myb_DNA-binding PF00249.31 ORY34463.1 - 0.0015 18.7 0.2 1.3 9.3 0.1 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY34463.1 - 0.091 13.0 1.0 3.2 8.1 0.0 2.7 2 1 1 3 3 3 0 Myb-like DNA-binding domain DUF5053 PF16476.5 ORY34463.1 - 0.12 12.0 0.3 5.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5053) PRANC PF09372.10 ORY34464.1 - 0.064 13.6 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 PRANC domain UBX PF00789.20 ORY34465.1 - 2.7e-17 62.7 0.1 5.9e-17 61.6 0.1 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 ORY34465.1 - 1.1e-07 31.5 0.0 2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain Presenilin PF01080.17 ORY34465.1 - 0.16 10.7 0.8 0.23 10.2 0.8 1.1 1 0 0 1 1 1 0 Presenilin FAM83 PF07894.12 ORY34465.1 - 0.18 11.3 1.8 0.27 10.7 1.8 1.2 1 0 0 1 1 1 0 FAM83 A-H YliH PF10799.8 ORY34465.1 - 0.31 11.0 1.5 0.59 10.1 1.5 1.4 1 0 0 1 1 1 0 Biofilm formation protein (YliH/bssR) MRP-S26 PF14943.6 ORY34465.1 - 1.2 9.0 14.9 11 5.8 16.4 1.7 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 Borrelia_P83 PF05262.11 ORY34465.1 - 4.2 5.8 11.1 5.9 5.3 11.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein FHA PF00498.26 ORY34467.1 - 1.1e-13 51.3 0.0 2.2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 ORY34467.1 - 4.3e-10 39.2 9.7 8.8e-10 38.2 9.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 ORY34467.1 - 6e-09 36.1 12.0 1e-08 35.4 12.0 1.4 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 ORY34467.1 - 0.00059 20.1 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-ANAPC11 PF12861.7 ORY34467.1 - 0.0013 18.7 5.4 0.0023 17.9 5.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 ORY34467.1 - 0.0028 17.6 12.2 0.0044 16.9 12.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY34467.1 - 0.0055 16.5 10.9 0.0086 15.9 10.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY34467.1 - 0.0067 16.7 8.3 0.014 15.6 8.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORY34467.1 - 0.0069 16.2 13.9 0.012 15.5 13.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 ORY34467.1 - 0.17 11.8 6.1 0.29 11.1 6.1 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 ORY34467.1 - 0.24 11.5 14.7 0.46 10.6 14.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger PIG-U PF06728.13 ORY34468.1 - 2.8e-101 339.3 22.5 3.3e-101 339.1 22.5 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U CPP1-like PF11833.8 ORY34468.1 - 0.21 11.2 0.6 0.56 9.8 0.6 1.7 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like 8TM_micro PF17028.5 ORY34468.1 - 0.23 11.1 18.0 0.019 14.7 13.3 1.5 2 0 0 2 2 2 0 8TM Microsporidial transmembrane domain DUF2106 PF09879.9 ORY34468.1 - 3 7.4 5.4 9.2 5.8 0.5 3.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2106) ADK PF00406.22 ORY34469.1 - 1.5e-36 125.7 0.1 1.7e-13 51.0 0.0 4.0 4 0 0 4 4 4 3 Adenylate kinase AAA_17 PF13207.6 ORY34469.1 - 4.8e-23 82.1 2.1 4.1e-09 37.0 0.0 5.2 5 2 1 6 6 5 3 AAA domain FAP206 PF12018.8 ORY34469.1 - 2.7e-18 66.5 0.1 2.4e-06 27.3 0.0 5.2 5 0 0 5 5 5 4 Domain of unknown function YHS PF04945.13 ORY34469.1 - 7.9e-15 54.7 2.7 0.0066 16.5 0.0 4.7 4 0 0 4 4 4 4 YHS domain AAA_18 PF13238.6 ORY34469.1 - 8.9e-08 32.7 0.1 0.15 12.6 0.0 4.5 3 1 1 4 4 4 2 AAA domain Hydin_ADK PF17213.3 ORY34469.1 - 1.4e-06 28.7 7.7 0.0033 17.7 0.0 3.4 5 0 0 5 5 4 2 Hydin Adenylate kinase-like domain AAA PF00004.29 ORY34469.1 - 7.9e-05 23.1 0.0 9.5 6.7 0.0 4.4 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 ORY34469.1 - 0.00085 19.6 0.0 4 7.7 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 ORY34469.1 - 0.0014 18.9 0.0 2.7 8.3 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 ORY34469.1 - 0.0037 17.4 0.0 2.1 8.5 0.0 3.5 4 0 0 4 4 4 1 AAA domain ABC_tran PF00005.27 ORY34469.1 - 0.024 15.1 0.0 0.93 10.0 0.0 2.9 3 0 0 3 3 2 0 ABC transporter AAA_24 PF13479.6 ORY34469.1 - 0.028 14.1 0.6 7.6 6.2 0.0 3.7 4 0 0 4 4 4 0 AAA domain Dpy-30 PF05186.13 ORY34469.1 - 0.042 13.6 0.1 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Dpy-30 motif Wbp11 PF09429.10 ORY34469.1 - 0.05 14.0 3.3 0.22 12.0 3.3 2.1 1 0 0 1 1 1 0 WW domain binding protein 11 RNA_helicase PF00910.22 ORY34469.1 - 0.13 12.7 0.1 39 4.7 0.0 3.0 3 0 0 3 3 2 0 RNA helicase MMR_HSR1 PF01926.23 ORY34469.1 - 0.15 12.1 0.0 8.7 6.5 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 ORY34469.1 - 0.2 11.3 0.0 5 6.7 0.0 2.3 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain CENP-B_dimeris PF09026.10 ORY34469.1 - 5.9 7.4 11.6 0.96 9.9 3.7 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CDC45 PF02724.14 ORY34469.1 - 8.5 4.5 8.2 17 3.6 8.2 1.4 1 0 0 1 1 1 0 CDC45-like protein Ras PF00071.22 ORY34470.1 - 1.8e-34 118.7 0.2 2.1e-34 118.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY34470.1 - 2.8e-25 88.9 0.3 4.4e-25 88.2 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY34470.1 - 6.2e-08 32.3 0.1 7.1e-08 32.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY34470.1 - 1.3e-06 27.9 0.2 1.7e-06 27.6 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 ORY34470.1 - 0.00017 20.5 0.1 0.23 10.3 0.0 2.0 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.23 ORY34470.1 - 0.019 15.0 0.0 0.067 13.3 0.0 1.9 1 1 1 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 ORY34470.1 - 0.027 14.2 0.2 0.1 12.3 0.2 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 ORY34470.1 - 0.027 13.6 1.9 0.072 12.2 0.1 2.3 1 1 1 2 2 2 0 G-protein alpha subunit Peptidase_A2E PF12382.8 ORY34470.1 - 0.03 14.3 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon peptidase SRPRB PF09439.10 ORY34470.1 - 0.03 13.7 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 ORY34470.1 - 0.055 12.9 0.0 1.5 8.2 0.0 2.3 2 1 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 ORY34470.1 - 0.23 11.0 1.4 0.34 10.4 0.1 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region M_domain PF12938.7 ORY34472.1 - 0.025 14.4 2.8 0.027 14.3 2.8 1.0 1 0 0 1 1 1 0 M domain of GW182 Helitron_like_N PF14214.6 ORY34474.1 - 7.5e-16 58.9 0.0 9.2e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF4368 PF14287.6 ORY34474.1 - 0.0071 16.6 0.1 0.019 15.3 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4368) AAA_30 PF13604.6 ORY34476.1 - 4.6e-14 52.6 0.0 4.8e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.14 ORY34476.1 - 1.3e-13 50.9 0.0 1.4e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.6 ORY34476.1 - 9.1e-12 45.5 0.1 1.8e-11 44.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 ORY34476.1 - 9.3e-06 24.8 0.0 1.1e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 ORY34476.1 - 0.00025 20.6 0.0 0.00031 20.3 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ATP_bind_1 PF03029.17 ORY34476.1 - 0.00035 20.4 0.0 0.0004 20.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 ORY34476.1 - 0.00035 20.5 0.1 0.14 12.1 0.0 2.1 2 0 0 2 2 2 1 NTPase AAA_14 PF13173.6 ORY34476.1 - 0.00078 19.5 0.0 0.0016 18.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORY34476.1 - 0.0011 18.6 0.1 0.002 17.8 0.1 1.5 1 1 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 ORY34476.1 - 0.0016 18.8 0.0 0.0034 17.7 0.0 1.6 1 1 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 ORY34476.1 - 0.0018 18.7 0.0 0.0019 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 ORY34476.1 - 0.0018 18.3 0.0 0.0052 16.8 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY34476.1 - 0.0023 18.2 0.5 0.019 15.3 0.5 2.0 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 ORY34476.1 - 0.0043 16.8 0.3 0.0093 15.7 0.3 1.6 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase APS_kinase PF01583.20 ORY34476.1 - 0.0052 16.7 0.2 0.012 15.5 0.2 1.6 1 1 0 1 1 1 1 Adenylylsulphate kinase DUF463 PF04317.12 ORY34476.1 - 0.011 14.8 0.1 0.012 14.6 0.1 1.1 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_11 PF13086.6 ORY34476.1 - 0.014 15.2 0.4 0.099 12.4 0.0 1.9 1 1 1 2 2 2 0 AAA domain T2SSE PF00437.20 ORY34476.1 - 0.017 14.2 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 ORY34476.1 - 0.02 14.6 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ORY34476.1 - 0.02 14.9 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 ORY34476.1 - 0.023 14.0 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.19 ORY34476.1 - 0.033 13.8 0.2 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Helicase_RecD PF05127.14 ORY34476.1 - 0.041 13.7 0.5 0.95 9.3 0.5 2.1 1 1 0 1 1 1 0 Helicase ATPase_2 PF01637.18 ORY34476.1 - 0.05 13.5 0.6 1.9 8.3 0.0 2.1 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 ORY34476.1 - 0.053 13.0 0.3 0.29 10.6 0.2 2.0 1 1 1 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 ORY34476.1 - 0.068 13.6 0.0 0.097 13.1 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 ORY34476.1 - 0.07 12.8 0.1 0.11 12.1 0.1 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain G-alpha PF00503.20 ORY34476.1 - 0.087 12.0 0.0 0.087 12.0 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit TniB PF05621.11 ORY34476.1 - 0.09 12.2 0.1 0.66 9.4 0.0 2.1 2 1 1 3 3 3 0 Bacterial TniB protein DUF2075 PF09848.9 ORY34476.1 - 0.093 11.9 0.2 0.13 11.5 0.2 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 ORY34476.1 - 0.11 13.1 0.4 0.16 12.5 0.4 1.5 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 ORY34476.1 - 0.14 11.8 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase rve PF00665.26 ORY34477.1 - 1e-06 29.0 0.0 1.9e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 ORY34477.1 - 1.3e-06 28.1 0.6 2.4e-06 27.3 0.6 1.4 1 0 0 1 1 1 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 ORY34478.1 - 3.2e-05 23.6 0.0 5.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type FlaF PF07309.11 ORY34478.1 - 0.0031 17.5 0.0 0.006 16.6 0.0 1.4 1 0 0 1 1 1 1 Flagellar protein FlaF Retrotrans_gag PF03732.17 ORY34478.1 - 0.0041 17.4 0.0 0.0062 16.8 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein DUF1367 PF07105.11 ORY34480.1 - 0.0049 16.6 0.0 0.0077 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1367) Tropomyosin PF00261.20 ORY34480.1 - 0.008 15.6 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 1 Tropomyosin SPRY PF00622.28 ORY34520.1 - 4.8e-11 42.8 0.1 6.7e-11 42.4 0.1 1.2 1 0 0 1 1 1 1 SPRY domain Neuralized PF07177.12 ORY34520.1 - 0.043 13.8 0.0 0.2 11.7 0.0 1.9 1 1 0 1 1 1 0 Neuralized Myosin_head PF00063.21 ORY34522.1 - 1.1e-246 820.3 4.2 1.6e-246 819.8 4.2 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 ORY34522.1 - 3.6e-21 75.4 0.9 3.1e-20 72.4 0.0 2.8 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 ORY34522.1 - 5.9e-11 41.2 10.5 1.6e-06 27.4 2.0 4.5 4 0 0 4 4 4 2 IQ calmodulin-binding motif MAD PF05557.13 ORY34522.1 - 1.5e-05 23.6 7.0 1.5e-05 23.6 7.0 1.8 2 0 0 2 2 2 1 Mitotic checkpoint protein DUF4201 PF13870.6 ORY34522.1 - 8e-05 22.4 6.7 8e-05 22.4 6.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) Spc7 PF08317.11 ORY34522.1 - 0.00062 18.8 9.2 0.00062 18.8 9.2 1.9 2 0 0 2 2 2 1 Spc7 kinetochore protein AAA_22 PF13401.6 ORY34522.1 - 0.0045 17.3 0.0 0.02 15.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY34522.1 - 0.034 14.5 0.0 0.13 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Csm4_C PF17953.1 ORY34522.1 - 0.073 12.9 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 CRISPR Csm4 C-terminal domain Tropomyosin_1 PF12718.7 ORY34522.1 - 0.095 12.9 10.1 0.3 11.2 10.1 1.9 1 0 0 1 1 1 0 Tropomyosin like ERM PF00769.19 ORY34522.1 - 0.34 10.7 17.6 0.74 9.6 17.6 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Laminin_I PF06008.14 ORY34522.1 - 0.87 9.2 16.6 0.018 14.7 9.5 1.7 2 0 0 2 2 2 0 Laminin Domain I DUF724 PF05266.14 ORY34522.1 - 8.1 6.2 8.9 19 5.0 8.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) PBP_like_2 PF12849.7 ORY34523.1 - 0.00039 20.2 0.6 0.00047 19.9 0.6 1.0 1 0 0 1 1 1 1 PBP superfamily domain Glyco_hydro_18 PF00704.28 ORY34525.1 - 1.5e-66 225.3 0.4 2e-66 224.9 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 tRNA-synt_1g PF09334.11 ORY34526.1 - 0.074 11.8 2.5 0.1 11.3 2.5 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) UQ_con PF00179.26 ORY34527.1 - 2.9e-43 146.9 0.2 3.3e-43 146.7 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY34527.1 - 0.0011 18.7 0.0 0.0018 18.0 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 ORY34527.1 - 0.027 14.8 0.0 0.028 14.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain DUF4097 PF13349.6 ORY34528.1 - 7.9e-10 38.5 2.0 1.1e-09 38.1 2.0 1.2 1 0 0 1 1 1 1 Putative adhesin LRR_8 PF13855.6 ORY34529.1 - 1.6e-17 63.0 24.6 5.7e-07 29.2 6.2 4.2 2 2 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 ORY34529.1 - 3.3e-11 43.2 18.7 0.0014 19.0 0.7 5.0 2 2 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY34529.1 - 6e-06 26.1 19.2 0.14 12.8 0.4 7.5 8 0 0 8 8 8 2 Leucine Rich Repeat F-box-like PF12937.7 ORY34529.1 - 0.0041 17.0 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 ORY34529.1 - 2.7 8.3 11.8 40 4.6 0.1 4.7 5 0 0 5 5 5 0 Leucine Rich repeat TPR_12 PF13424.6 ORY34530.1 - 1.4e-74 246.4 36.5 1.1e-15 57.7 0.1 7.6 3 2 6 9 9 9 9 Tetratricopeptide repeat TPR_10 PF13374.6 ORY34530.1 - 5.6e-49 162.8 15.0 7.9e-08 31.9 0.0 11.4 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_7 PF13176.6 ORY34530.1 - 9e-24 81.7 12.9 0.007 16.3 0.0 11.2 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY34530.1 - 2.1e-15 55.5 24.9 0.39 10.9 0.8 10.7 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 ORY34530.1 - 5.2e-14 51.4 17.8 0.16 11.9 0.0 9.6 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORY34530.1 - 3.3e-13 48.7 26.3 0.2 11.9 0.0 11.5 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_16 PF13432.6 ORY34530.1 - 1.6e-12 47.9 7.6 2.1 9.1 0.1 8.9 9 1 0 9 9 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY34530.1 - 4e-12 45.9 6.8 1.1 10.2 0.0 9.5 9 1 1 10 10 9 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY34530.1 - 3.6e-11 43.0 11.9 2.7e-06 27.0 6.2 4.1 1 1 2 3 3 3 2 MalT-like TPR region TPR_4 PF07721.14 ORY34530.1 - 7.8e-08 32.2 0.0 6.1 7.8 0.0 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY34530.1 - 2.4e-05 24.8 16.3 1.1 9.8 0.6 7.8 4 2 6 10 10 9 3 Tetratricopeptide repeat TPR_5 PF12688.7 ORY34530.1 - 0.00024 21.3 2.7 0.13 12.5 0.2 4.1 3 1 1 4 4 4 1 Tetratrico peptide repeat RPN7 PF10602.9 ORY34530.1 - 0.0011 18.7 4.8 0.092 12.5 0.0 5.2 4 3 4 8 8 8 1 26S proteasome subunit RPN7 TPR_6 PF13174.6 ORY34530.1 - 0.0033 17.9 18.6 11 6.9 0.1 9.9 10 1 0 10 10 10 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORY34530.1 - 0.0054 17.0 15.6 1.3 9.6 0.1 7.4 8 0 0 8 8 7 1 Tetratricopeptide repeat RPN6_N PF18055.1 ORY34530.1 - 0.025 15.0 1.0 2 8.8 0.1 4.1 3 1 1 4 4 4 0 26S proteasome regulatory subunit RPN6 N-terminal domain PPR PF01535.20 ORY34530.1 - 0.026 14.7 6.5 21 5.6 0.0 6.1 6 0 0 6 6 6 0 PPR repeat SNAP PF14938.6 ORY34530.1 - 0.028 13.9 2.4 1.2 8.5 0.0 3.7 2 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP BTAD PF03704.17 ORY34530.1 - 0.69 10.3 4.8 5.1 7.5 0.6 4.0 3 2 2 5 5 5 0 Bacterial transcriptional activator domain TPR_11 PF13414.6 ORY34530.1 - 2.2 8.0 8.2 1.7 8.4 0.1 4.8 7 0 0 7 7 7 0 TPR repeat MFS_1 PF07690.16 ORY34531.1 - 2.9e-18 65.9 53.3 2.2e-10 40.0 13.3 3.2 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.6 ORY34531.1 - 0.00065 18.4 35.5 0.006 15.2 13.9 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein CRM1_C PF08767.11 ORY34532.1 - 8.6e-87 291.3 24.9 6.5e-84 281.8 13.7 5.5 3 1 0 3 3 3 2 CRM1 C terminal Xpo1 PF08389.12 ORY34532.1 - 4.7e-44 150.1 9.6 1.6e-43 148.3 7.4 3.1 2 0 0 2 2 2 1 Exportin 1-like protein CRM1_repeat_3 PF18787.1 ORY34532.1 - 2.7e-28 97.8 3.1 4.7e-28 97.1 1.0 2.4 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 ORY34532.1 - 2.8e-19 68.3 1.3 9.2e-19 66.7 1.3 2.0 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat CRM1_repeat_2 PF18784.1 ORY34532.1 - 6.6e-17 60.9 2.7 4e-16 58.4 2.7 2.4 1 1 0 1 1 1 1 CRM1 / Exportin repeat 2 IBN_N PF03810.19 ORY34532.1 - 9.1e-07 28.7 5.1 2e-06 27.6 0.8 3.3 3 1 0 3 3 3 1 Importin-beta N-terminal domain BID PF06393.11 ORY34532.1 - 0.066 12.8 0.1 0.35 10.4 0.0 2.2 2 0 0 2 2 2 0 BH3 interacting domain (BID) WD40_alt PF14077.6 ORY34532.1 - 1.9 8.4 4.9 2.6 8.0 0.1 3.1 3 0 0 3 3 3 0 Alternative WD40 repeat motif Prolamin_like PF05617.11 ORY34532.1 - 9.1 6.5 6.4 98 3.2 0.3 4.1 3 1 0 4 4 4 0 Prolamin-like Helicase_C PF00271.31 ORY34534.1 - 0.01 16.2 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-H2C2_2 PF13465.6 ORY34537.1 - 2.8e-13 49.6 4.0 1.4e-05 25.3 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY34537.1 - 4.7e-11 42.5 15.1 0.001 19.4 1.2 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY34537.1 - 1e-06 29.0 14.0 0.0035 18.1 0.9 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORY34537.1 - 5.9e-05 22.7 8.8 0.15 11.9 1.0 3.5 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 ORY34537.1 - 0.0091 16.3 6.8 0.0095 16.2 3.7 2.1 1 1 1 2 2 2 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 ORY34537.1 - 0.021 15.5 2.8 0.027 15.1 0.4 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain Glyco_hydro_64 PF16483.5 ORY34537.1 - 0.036 13.3 0.0 0.04 13.2 0.0 1.1 1 0 0 1 1 1 0 Beta-1,3-glucanase zf-C2H2_jaz PF12171.8 ORY34537.1 - 0.043 14.1 0.5 0.26 11.6 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY34537.1 - 0.074 13.1 0.3 0.074 13.1 0.3 3.4 4 0 0 4 4 3 0 C2H2-type zinc finger zf-C2HE PF16278.5 ORY34537.1 - 0.074 13.5 7.2 0.18 12.2 0.1 3.0 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger C1_4 PF07975.12 ORY34537.1 - 0.11 12.7 2.4 0.22 11.8 2.4 1.6 1 1 0 1 1 1 0 TFIIH C1-like domain F-box_4 PF15966.5 ORY34539.1 - 0.027 14.4 0.1 0.053 13.4 0.1 1.5 1 0 0 1 1 1 0 F-box PIF1 PF05970.14 ORY35137.1 - 0.18 10.9 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Pacs-1 PF10254.9 ORY35138.1 - 0.029 13.3 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein ATP12 PF07542.11 ORY35139.1 - 2.2e-34 118.3 0.0 3.7e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein MRP-S34 PF16053.5 ORY35140.1 - 4.6e-08 32.8 0.0 7.1e-08 32.2 0.0 1.3 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S34 Brix PF04427.18 ORY35141.1 - 4.6e-32 111.7 0.1 6.4e-32 111.2 0.1 1.2 1 0 0 1 1 1 1 Brix domain RE_HindVP PF09519.10 ORY35141.1 - 0.14 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 HindVP restriction endonuclease bZIP_2 PF07716.15 ORY35142.1 - 2.7e-09 37.0 12.0 2.7e-09 37.0 12.0 3.0 2 1 1 3 3 3 2 Basic region leucine zipper RasGAP_C PF03836.15 ORY35142.1 - 0.0015 18.7 4.8 0.003 17.7 4.8 1.5 1 0 0 1 1 1 1 RasGAP C-terminus bZIP_1 PF00170.21 ORY35142.1 - 0.006 16.7 11.2 0.006 16.7 11.2 2.7 3 0 0 3 3 3 1 bZIP transcription factor NAM-associated PF14303.6 ORY35142.1 - 0.01 16.6 5.3 0.01 16.6 5.3 1.9 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain Cep57_CLD_2 PF14197.6 ORY35142.1 - 0.018 15.1 5.1 0.069 13.2 5.1 2.2 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 HemX PF04375.14 ORY35142.1 - 0.052 12.8 6.6 0.1 11.8 6.6 1.4 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Serglycin PF04360.12 ORY35142.1 - 0.055 13.4 3.5 0.14 12.1 3.5 1.7 1 0 0 1 1 1 0 Serglycin FlaC_arch PF05377.11 ORY35142.1 - 0.26 11.7 3.0 0.91 10.0 3.0 2.0 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF4094 PF13334.6 ORY35142.1 - 0.43 11.0 4.1 1.2 9.6 2.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) DUF5094 PF17015.5 ORY35142.1 - 1.4 9.0 8.7 0.11 12.6 3.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) WASH-7_C PF14746.6 ORY35142.1 - 3.4 7.3 9.1 2.3 7.9 6.8 1.8 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal RRS1 PF04939.12 ORY35143.1 - 5.2e-12 45.9 9.6 5.2e-12 45.9 9.6 2.2 2 1 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) WD40 PF00400.32 ORY35144.1 - 7e-13 48.8 5.1 0.022 15.7 0.1 5.9 5 0 0 5 5 5 4 WD domain, G-beta repeat SRA1 PF07304.11 ORY35144.1 - 1.2e-07 31.7 0.1 1.2e-07 31.7 0.1 4.7 5 1 1 6 6 6 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.15 ORY35144.1 - 2.2e-07 31.0 0.1 5.1e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 Prp18 domain ANAPC4_WD40 PF12894.7 ORY35144.1 - 2.3e-05 24.6 0.1 2.3 8.6 0.0 4.6 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain TPR_MLP1_2 PF07926.12 ORY35145.1 - 0.00072 19.6 8.9 0.0011 19.0 8.9 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Bacillus_HBL PF05791.11 ORY35145.1 - 0.012 15.4 2.6 0.024 14.4 2.4 1.6 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DNA_Packaging PF11053.8 ORY35145.1 - 0.078 12.8 0.5 0.12 12.2 0.5 1.5 1 0 0 1 1 1 0 Terminase DNA packaging enzyme Med9 PF07544.13 ORY35145.1 - 0.087 12.9 6.4 0.15 12.1 6.4 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 ALMT PF11744.8 ORY35145.1 - 0.16 10.8 3.4 0.16 10.7 3.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter FapA PF03961.13 ORY35145.1 - 0.32 9.6 6.8 0.37 9.4 6.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 ORY35145.1 - 0.4 9.9 6.1 0.51 9.5 6.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein ATPase_2 PF01637.18 ORY35145.1 - 0.56 10.1 7.2 0.75 9.7 7.2 1.1 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Rootletin PF15035.6 ORY35145.1 - 1.8 8.5 12.8 11 6.0 12.8 1.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion LRR_9 PF14580.6 ORY35146.1 - 7e-17 61.5 6.1 1.2e-16 60.8 6.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 ORY35146.1 - 9.4e-10 38.6 30.9 2.6e-06 27.7 8.8 3.7 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY35146.1 - 9.7e-07 28.5 22.6 1.2e-05 24.9 8.6 2.9 1 1 3 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 ORY35146.1 - 0.0017 18.3 3.1 6.1 7.2 0.1 3.7 3 0 0 3 3 3 2 Leucine Rich repeat Presenilin PF01080.17 ORY35146.1 - 0.38 9.5 1.3 0.63 8.7 1.3 1.2 1 0 0 1 1 1 0 Presenilin SBDS_C PF09377.10 ORY35147.1 - 4.7e-38 129.8 1.1 9.7e-38 128.8 1.1 1.5 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 ORY35147.1 - 5.6e-34 116.1 0.9 1.4e-33 114.8 0.9 1.7 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein B2-adapt-app_C PF09066.10 ORY35147.1 - 0.021 14.9 1.2 4.6 7.4 0.1 2.3 2 0 0 2 2 2 0 Beta2-adaptin appendage, C-terminal sub-domain Alk_phosphatase PF00245.20 ORY35149.1 - 2.1e-50 171.9 0.2 4.2e-50 170.9 0.2 1.5 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 ORY35149.1 - 0.0028 17.1 0.0 0.0093 15.4 0.0 1.8 2 0 0 2 2 2 1 Metalloenzyme superfamily Nfu_N PF08712.11 ORY35150.1 - 3.3e-29 100.8 0.0 1.4e-28 98.7 0.0 1.9 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 ORY35150.1 - 6.5e-27 93.5 0.1 1.3e-26 92.5 0.1 1.5 1 0 0 1 1 1 1 NifU-like domain IMD PF08397.11 ORY35150.1 - 0.035 13.5 0.1 0.047 13.1 0.1 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain WD40 PF00400.32 ORY35151.1 - 6.2e-44 147.1 17.2 1.2e-08 35.5 0.3 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY35151.1 - 2.3e-28 98.3 4.5 9.8e-08 32.2 0.3 5.5 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 ORY35151.1 - 2.9e-09 36.5 0.2 6e-09 35.6 0.2 1.6 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 ORY35151.1 - 6.4e-07 29.4 1.4 0.011 15.7 0.0 3.5 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 ORY35151.1 - 0.00014 20.1 1.2 0.00031 18.9 0.1 1.9 1 1 1 2 2 2 1 IKI3 family DUF1616 PF07760.11 ORY35152.1 - 0.00021 20.8 0.0 0.00028 20.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1616) Methyltransf_5 PF01795.19 ORY35153.1 - 1.1e-82 278.0 0.0 4.7e-73 246.4 0.0 2.4 2 1 0 2 2 2 2 MraW methylase family Methyltransf_25 PF13649.6 ORY35153.1 - 0.01 16.5 0.0 0.036 14.8 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 ORY35153.1 - 0.026 14.6 0.0 0.33 11.1 0.0 2.2 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 ORY35153.1 - 0.034 14.9 0.0 0.47 11.2 0.0 2.8 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_31 PF13847.6 ORY35153.1 - 0.13 12.1 0.1 0.65 9.8 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain UDPG_MGDP_dh PF00984.19 ORY35154.1 - 0.025 14.8 0.1 0.05 13.8 0.1 1.6 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, central domain PPR_long PF17177.4 ORY35154.1 - 0.046 13.1 0.2 0.21 10.9 0.2 1.8 1 1 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP Endotoxin_C2 PF18449.1 ORY35154.1 - 0.13 12.6 1.0 0.22 11.9 1.0 1.3 1 0 0 1 1 1 0 Delta endotoxin Cas_St_Csn2 PF16813.5 ORY35154.1 - 0.14 11.2 0.1 0.19 10.8 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Csn2 subfamily St Pkinase PF00069.25 ORY35155.1 - 8.7e-49 166.3 0.0 5.1e-48 163.7 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY35155.1 - 8.5e-22 77.7 0.0 1.9e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY35155.1 - 0.00058 18.8 0.3 0.0015 17.4 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 ORY35155.1 - 0.0006 19.8 1.0 0.073 13.0 0.2 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY35155.1 - 0.004 16.5 0.0 0.011 15.1 0.0 1.8 1 0 0 1 1 1 1 Kinase-like Oxysterol_BP PF01237.18 ORY35157.1 - 7e-49 166.6 0.9 3e-29 102.0 0.8 3.5 2 1 0 2 2 2 2 Oxysterol-binding protein ABC_membrane PF00664.23 ORY35158.1 - 1.4e-44 152.9 39.6 5.3e-27 95.2 16.9 3.2 2 1 1 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY35158.1 - 2.5e-35 121.9 0.1 3.9e-18 66.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_16 PF13191.6 ORY35158.1 - 8.9e-08 32.7 0.1 0.013 15.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 ORY35158.1 - 1e-07 32.1 0.6 0.00056 19.8 0.0 2.7 3 0 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY35158.1 - 1.5e-07 31.1 1.8 0.0012 18.5 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY35158.1 - 2.4e-06 27.6 0.8 0.014 15.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 ORY35158.1 - 3.3e-06 26.7 2.0 0.24 10.8 0.1 4.2 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 ORY35158.1 - 4e-06 27.0 0.4 0.022 14.9 0.0 2.3 2 0 0 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 ORY35158.1 - 1.1e-05 25.5 0.6 0.02 14.8 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 ORY35158.1 - 0.00018 21.8 0.1 0.6 10.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.6 ORY35158.1 - 0.00019 22.0 4.4 0.091 13.3 0.2 2.7 3 0 0 3 3 2 2 AAA domain KAP_NTPase PF07693.14 ORY35158.1 - 0.00089 18.6 0.0 1.1 8.4 0.0 2.4 2 0 0 2 2 2 2 KAP family P-loop domain AAA_7 PF12775.7 ORY35158.1 - 0.0017 17.9 0.2 0.53 9.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 ORY35158.1 - 0.0077 16.2 0.3 1.7 8.6 0.1 2.4 2 0 0 2 2 2 1 NACHT domain AAA_PrkA PF08298.11 ORY35158.1 - 0.0077 15.2 0.0 0.044 12.7 0.0 2.0 2 0 0 2 2 2 1 PrkA AAA domain NB-ARC PF00931.22 ORY35158.1 - 0.0077 15.4 0.3 3.6 6.7 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain DUF5366 PF17328.2 ORY35158.1 - 0.013 15.6 1.5 0.013 15.6 1.5 3.5 3 2 1 4 4 4 0 Family of unknown function (DUF5366) TsaE PF02367.17 ORY35158.1 - 0.016 15.2 0.4 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 ORY35158.1 - 0.031 13.9 3.3 0.91 9.1 0.1 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain HobA PF12163.8 ORY35158.1 - 0.04 13.5 0.0 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 DNA replication regulator AAA_30 PF13604.6 ORY35158.1 - 0.046 13.4 2.0 4.1 7.1 0.1 2.8 3 1 0 3 3 3 0 AAA domain AAA_25 PF13481.6 ORY35158.1 - 0.068 12.7 0.1 3.2 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORY35158.1 - 0.069 13.5 0.0 16 6.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_35 PF14516.6 ORY35158.1 - 0.091 11.6 0.1 0.34 9.7 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain T2SSE PF00437.20 ORY35158.1 - 0.1 11.7 0.1 9.2 5.2 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 ORY35158.1 - 0.13 11.6 0.3 0.48 9.7 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 ORY35158.1 - 0.18 11.1 0.2 7.5 5.8 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin Roc PF08477.13 ORY35158.1 - 0.19 12.0 0.3 14 5.9 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 ORY35158.1 - 0.62 9.7 3.4 2.3 7.9 0.2 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 ORY35158.1 - 0.8 9.7 5.2 0.31 11.1 0.6 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain Lipase_GDSL_2 PF13472.6 ORY35161.1 - 0.081 13.3 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF4903 PF16246.5 ORY35161.1 - 0.18 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4903) Acyltransferase PF01553.21 ORY35162.1 - 8.4e-13 48.1 0.0 1.4e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 ORY35162.1 - 8.8e-06 25.7 0.1 1.8e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Methyltransf_16 PF10294.9 ORY35163.1 - 3.4e-13 49.7 0.1 6.9e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 ORY35163.1 - 8e-09 35.3 0.0 1.3e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 ORY35163.1 - 6.7e-05 23.5 0.0 0.00015 22.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY35163.1 - 0.01 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 ORY35163.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.7 ORY35163.1 - 0.018 15.0 0.0 0.05 13.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 ORY35163.1 - 0.074 13.7 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Phosphoesterase PF04185.14 ORY35164.1 - 3.2e-22 79.2 0.5 1.3e-11 44.4 0.2 2.8 1 1 2 3 3 3 3 Phosphoesterase family NAD_binding_1 PF00175.21 ORY35165.1 - 1.9e-10 41.3 0.1 2.4e-07 31.4 0.1 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 ORY35165.1 - 5.5e-07 29.8 0.2 3e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 ORY35165.1 - 0.0042 17.4 0.0 0.77 10.1 0.0 2.3 1 1 1 2 2 2 2 Oxidoreductase FAD-binding domain PTR2 PF00854.21 ORY35166.1 - 2.1e-54 184.9 10.8 1.6e-51 175.4 10.8 2.8 1 1 0 1 1 1 1 POT family Pyridox_ox_2 PF12900.7 ORY35167.1 - 3.1e-34 118.0 0.1 3.9e-34 117.7 0.1 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase zf-H2C2_5 PF13909.6 ORY35168.1 - 0.12 12.1 1.6 0.29 10.9 1.6 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain G8 PF10162.9 ORY35169.1 - 9.4e-26 90.3 0.6 2.1e-25 89.1 0.6 1.6 1 0 0 1 1 1 1 G8 domain LRR_8 PF13855.6 ORY35170.1 - 8.7e-18 63.8 50.7 6.1e-08 32.3 12.0 3.9 2 1 4 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 ORY35170.1 - 2e-11 43.9 22.5 3.7e-06 27.2 4.4 3.9 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY35170.1 - 8.4e-08 31.7 25.4 0.12 13.0 0.7 6.5 5 1 0 5 5 5 4 Leucine Rich Repeat F-box-like PF12937.7 ORY35170.1 - 0.002 18.0 3.1 0.002 18.0 3.1 3.4 3 2 0 3 3 3 1 F-box-like F-box PF00646.33 ORY35170.1 - 0.038 13.9 0.2 0.15 12.0 0.2 2.1 1 0 0 1 1 1 0 F-box domain LRR_9 PF14580.6 ORY35170.1 - 0.65 9.5 7.4 1.1 8.7 2.7 2.2 1 1 1 2 2 2 0 Leucine-rich repeat Rap_GAP PF02145.15 ORY35171.1 - 5.5e-36 123.9 0.0 9.1e-36 123.1 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 ORY35171.1 - 1.2e-28 100.3 2.3 2.5e-28 99.2 0.1 2.2 2 0 0 2 2 2 1 Tuberin Pyridox_ox_2 PF12900.7 ORY35172.1 - 6.4e-34 117.0 0.1 9e-34 116.5 0.1 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase SET PF00856.28 ORY35173.1 - 1.5e-07 31.9 0.0 2.4e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 ORY35173.1 - 0.0004 21.1 0.0 0.00067 20.3 0.0 1.3 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Cu_amine_oxidN1 PF07833.11 ORY35173.1 - 0.024 15.1 0.1 0.041 14.4 0.1 1.4 1 0 0 1 1 1 0 Copper amine oxidase N-terminal domain SWM_repeat PF13753.6 ORY35173.1 - 0.029 14.5 0.1 0.083 13.0 0.1 1.8 1 1 1 2 2 2 0 Putative flagellar system-associated repeat DUF2067 PF09840.9 ORY35173.1 - 0.092 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) Mito_carr PF00153.27 ORY35175.1 - 2e-45 152.6 0.2 1.8e-21 75.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein GAD-like PF08887.11 ORY35175.1 - 0.044 13.6 0.1 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 GAD-like domain Cpn60_TCP1 PF00118.24 ORY35176.1 - 3.1e-96 322.9 2.1 1e-86 291.6 1.4 2.6 2 1 0 2 2 2 2 TCP-1/cpn60 chaperonin family DUF3674 PF12426.8 ORY35180.1 - 2.1 8.5 7.7 18 5.5 0.3 3.2 3 0 0 3 3 3 0 RNA dependent RNA polymerase adh_short PF00106.25 ORY35183.1 - 2.6e-19 69.5 0.4 7.9e-18 64.6 0.4 2.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY35183.1 - 2.1e-10 40.6 0.2 1.6e-09 37.7 0.2 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ORY35183.1 - 0.00035 20.1 0.7 0.0011 18.5 0.7 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 ORY35183.1 - 0.0059 16.5 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 KR domain AMP-binding PF00501.28 ORY35184.1 - 2.1e-92 309.9 0.0 2.7e-92 309.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme CRCB PF02537.15 ORY35185.1 - 0.026 14.8 0.6 0.026 14.8 0.6 1.8 2 1 0 2 2 2 0 CrcB-like protein, Camphor Resistance (CrcB) DUF2207 PF09972.9 ORY35185.1 - 0.071 11.9 2.2 0.12 11.1 2.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) GlpM PF06942.12 ORY35185.1 - 0.51 10.8 10.8 0.26 11.8 7.7 2.1 1 1 1 2 2 2 0 GlpM protein DUF996 PF06195.13 ORY35185.1 - 3.3 8.0 11.7 0.32 11.3 6.5 1.8 1 1 0 2 2 2 0 Protein of unknown function (DUF996) DUF627 PF04781.12 ORY35186.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Erv26 PF04148.13 ORY35187.1 - 2.6e-31 109.1 5.9 5.7e-31 108.0 5.9 1.5 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 Guanylate_cyc PF00211.20 ORY35188.1 - 6.2e-23 81.4 0.0 1.1e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pkinase_Tyr PF07714.17 ORY35188.1 - 2e-12 47.0 0.0 4.8e-12 45.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Tropomyosin_1 PF12718.7 ORY35188.1 - 0.094 12.9 2.6 0.18 11.9 2.6 1.5 1 0 0 1 1 1 0 Tropomyosin like CCDC-167 PF15188.6 ORY35188.1 - 0.23 11.8 5.8 5 7.5 0.1 3.0 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 DUF1664 PF07889.12 ORY35188.1 - 0.24 11.5 1.3 0.65 10.0 1.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 ORY35188.1 - 2.6 7.5 6.5 2.2 7.8 2.7 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit PTR2 PF00854.21 ORY35189.1 - 7e-61 206.2 13.8 7e-61 206.2 13.8 2.2 2 1 0 2 2 2 1 POT family Glyco_hydro_47 PF01532.20 ORY35190.1 - 2.2e-106 356.5 0.6 4.3e-106 355.6 0.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Acetyltransf_2 PF00797.17 ORY35190.1 - 7e-16 58.7 0.3 1.7e-07 31.3 0.0 3.5 3 0 0 3 3 3 2 N-acetyltransferase Glyco_hydro_76 PF03663.14 ORY35190.1 - 0.00047 19.8 0.7 0.31 10.5 0.1 2.7 2 1 0 2 2 2 2 Glycosyl hydrolase family 76 Acetyltransf_2 PF00797.17 ORY35191.1 - 3.4e-18 66.3 0.0 1e-17 64.8 0.0 1.6 1 1 0 1 1 1 1 N-acetyltransferase DUF1947 PF09183.10 ORY35191.1 - 0.21 11.9 0.1 0.43 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) Acetyltransf_10 PF13673.7 ORY35192.1 - 4.9e-09 36.2 0.0 1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY35192.1 - 5.6e-09 36.3 0.0 1.2e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY35192.1 - 3.1e-08 33.9 0.0 5.3e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 ORY35192.1 - 2.4e-05 24.2 0.0 0.00042 20.2 0.0 2.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 ORY35192.1 - 0.00051 20.1 0.0 0.0012 18.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 ORY35192.1 - 0.085 12.4 0.1 0.16 11.5 0.1 1.4 1 1 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_2 PF00797.17 ORY35193.1 - 3.2e-61 207.2 0.0 6.3e-33 114.6 0.0 2.1 2 0 0 2 2 2 2 N-acetyltransferase Tox-PLDMTX PF15645.6 ORY35193.1 - 0.017 15.4 0.0 0.21 11.8 0.0 2.2 2 0 0 2 2 2 0 Dermonecrotoxin of the Papain-like fold Transglut_core PF01841.19 ORY35193.1 - 0.034 14.6 0.0 1.7 9.1 0.0 2.3 2 0 0 2 2 2 0 Transglutaminase-like superfamily Glyoxalase PF00903.25 ORY35194.1 - 0.003 17.8 0.1 0.019 15.2 0.1 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF3853 PF12964.7 ORY35194.1 - 0.18 12.0 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) DWNN PF08783.11 ORY35195.1 - 3.8e-29 100.8 0.1 6.7e-29 100.0 0.1 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 ORY35195.1 - 8.6e-08 31.9 5.8 8.6e-08 31.9 5.8 2.5 3 0 0 3 3 3 1 Zinc knuckle zf-RING_2 PF13639.6 ORY35195.1 - 0.0012 19.1 10.3 0.0012 19.1 10.3 1.7 2 0 0 2 2 2 1 Ring finger domain zf-CCHC PF00098.23 ORY35195.1 - 0.0035 17.4 2.3 0.0035 17.4 2.3 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-RING_5 PF14634.6 ORY35195.1 - 0.0093 15.9 12.7 0.0093 15.9 12.7 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY35195.1 - 0.02 14.8 11.6 0.044 13.6 11.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY35195.1 - 0.53 10.2 18.3 0.029 14.2 10.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY35195.1 - 0.76 9.7 15.5 0.049 13.5 9.3 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ATG22 PF11700.8 ORY35196.1 - 9e-63 212.6 19.1 1.2e-62 212.1 19.1 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 ORY35196.1 - 0.00026 20.1 32.5 0.005 15.8 12.7 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily Y_phosphatase2 PF03162.13 ORY35197.1 - 1.8e-14 53.7 0.0 2.2e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family ATG22 PF11700.8 ORY35198.1 - 3.5e-42 144.6 16.5 4.8e-35 121.1 11.1 2.6 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like PTR2 PF00854.21 ORY35199.1 - 9.7e-36 123.4 10.3 2.6e-31 108.8 4.3 3.5 2 2 1 3 3 3 2 POT family TAF1_subA PF14929.6 ORY35200.1 - 8.1e-22 78.1 0.5 1.2e-21 77.6 0.5 1.1 1 0 0 1 1 1 1 TAF RNA Polymerase I subunit A PTR2 PF00854.21 ORY35201.1 - 3e-27 95.5 7.2 3e-26 92.2 7.2 2.0 1 1 0 1 1 1 1 POT family DUF5413 PF17434.2 ORY35201.1 - 1.6 9.0 6.6 12 6.2 0.2 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5413) Glyco_trans_1_4 PF13692.6 ORY35203.1 - 3.4e-09 37.2 0.0 6.7e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 ORY35203.1 - 4.3e-07 29.6 0.0 6.7e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORY35203.1 - 0.003 17.6 0.1 0.0053 16.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 TMEM171 PF15471.6 ORY35204.1 - 0.03 13.3 0.9 0.049 12.6 0.0 1.8 2 0 0 2 2 2 0 Transmembrane protein family 171 EIIC-GAT PF03611.14 ORY35204.1 - 0.037 13.1 6.2 0.074 12.1 5.9 1.8 1 1 0 1 1 1 0 PTS system sugar-specific permease component DUF2818 PF10993.8 ORY35204.1 - 0.06 13.9 0.8 0.06 13.9 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2818) DUF1129 PF06570.11 ORY35204.1 - 0.14 11.7 10.0 0.3 10.6 1.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1129) NapE PF06796.11 ORY35204.1 - 0.45 10.1 0.0 0.45 10.1 0.0 3.0 4 0 0 4 4 4 0 Periplasmic nitrate reductase protein NapE Pho86 PF11124.8 ORY35204.1 - 0.94 8.9 9.1 0.2 11.1 0.7 2.2 2 0 0 2 2 2 0 Inorganic phosphate transporter Pho86 PTPLA PF04387.14 ORY35205.1 - 0.14 11.9 14.0 0.27 10.9 0.3 2.7 1 1 2 3 3 3 0 Protein tyrosine phosphatase-like protein, PTPLA RIC3 PF15361.6 ORY35205.1 - 0.2 12.1 0.1 0.58 10.6 0.0 1.7 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Per1 PF04080.13 ORY35205.1 - 1.8 8.3 9.5 59 3.3 9.5 2.3 1 1 0 1 1 1 0 Per1-like family ECF_trnsprt PF12822.7 ORY35205.1 - 6 6.9 14.4 0.57 10.3 8.7 2.1 1 1 1 2 2 2 0 ECF transporter, substrate-specific component TctB PF07331.11 ORY35206.1 - 0.024 14.9 7.5 0.018 15.3 5.5 1.9 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family CobS PF02654.15 ORY35206.1 - 2.2 8.4 8.8 0.12 12.5 1.9 2.3 1 1 1 2 2 2 0 Cobalamin-5-phosphate synthase Solute_trans_a PF03619.16 ORY35206.1 - 3.2 7.2 15.3 22 4.5 15.3 2.0 1 1 0 1 1 1 0 Organic solute transporter Ostalpha UPF0697 PF15117.6 ORY35207.1 - 0.076 13.1 0.9 0.16 12.0 0.3 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0697 7tm_1 PF00001.21 ORY35207.1 - 0.12 11.7 10.7 0.073 12.4 8.5 1.6 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) Abhydrolase_9_N PF15420.6 ORY35207.1 - 4.5 7.2 5.8 15 5.5 3.6 2.5 1 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF378 PF04070.12 ORY35207.1 - 7.6 6.5 11.4 1.2 9.1 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF378) CCDC32 PF14989.6 ORY35208.1 - 9.3e-05 22.5 0.2 0.00014 21.8 0.2 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing 32 DUF4245 PF14030.6 ORY35208.1 - 0.038 14.0 1.7 0.043 13.8 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) Tex_YqgF PF16921.5 ORY35209.1 - 0.0034 17.8 0.2 0.0064 16.9 0.2 1.6 1 0 0 1 1 1 1 Tex protein YqgF-like domain Nuc_recep-AF1 PF11825.8 ORY35209.1 - 0.11 12.5 1.8 0.19 11.8 1.8 1.4 1 0 0 1 1 1 0 Nuclear/hormone receptor activator site AF-1 DUF2079 PF09852.9 ORY35209.1 - 0.19 10.5 0.7 0.26 10.1 0.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) ketoacyl-synt PF00109.26 ORY35211.1 - 1.1e-62 211.9 0.2 1.7e-62 211.3 0.2 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 ORY35211.1 - 1.2e-37 128.5 0.1 1.7e-36 124.8 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 ORY35211.1 - 5.9e-06 25.8 0.1 1.8e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 ORY35211.1 - 0.07 13.0 3.0 4.3 7.3 0.1 3.2 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III B_lectin PF01453.24 ORY35212.1 - 0.0085 16.6 2.8 3.8 8.1 0.7 2.5 1 1 1 2 2 2 2 D-mannose binding lectin Coatomer_WDAD PF04053.14 ORY35212.1 - 0.01 14.9 0.1 0.013 14.6 0.1 1.0 1 0 0 1 1 1 0 Coatomer WD associated region TraW_N PF12477.8 ORY35213.1 - 0.0015 18.4 0.1 2.6 8.1 0.1 2.8 2 0 0 2 2 2 2 Sex factor F TraW protein N terminal Coatomer_WDAD PF04053.14 ORY35213.1 - 0.035 13.1 0.4 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Coatomer WD associated region Peptidase_S3 PF00944.19 ORY35213.1 - 0.069 12.9 2.7 5.3 6.8 0.2 2.4 2 0 0 2 2 2 0 Alphavirus core protein B_lectin PF01453.24 ORY35213.1 - 0.13 12.8 6.3 2.2 8.9 0.3 3.3 2 2 2 4 4 4 0 D-mannose binding lectin Minor_tail_Z PF06763.11 ORY35213.1 - 0.27 11.0 0.3 11 5.8 0.0 2.2 2 0 0 2 2 2 0 Prophage minor tail protein Z (GPZ) DUF995 PF06191.12 ORY35213.1 - 9.1 6.0 10.1 6.6 6.4 1.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF995) B_lectin PF01453.24 ORY35214.1 - 0.048 14.2 0.2 0.8 10.3 0.0 2.3 1 1 1 2 2 2 0 D-mannose binding lectin DUF5538 PF17692.1 ORY35216.1 - 0.046 13.8 0.1 0.07 13.2 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5538) WD40 PF00400.32 ORY35217.1 - 4.7e-08 33.6 8.7 0.00064 20.5 0.5 5.6 5 1 1 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY35217.1 - 0.00018 21.7 0.0 1.8 8.9 0.0 3.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF896 PF05979.12 ORY35217.1 - 0.11 12.4 0.2 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) RRM_1 PF00076.22 ORY35218.1 - 3.1e-83 273.6 2.9 1.7e-22 79.0 0.3 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 ORY35218.1 - 2.4e-24 85.3 0.3 1.9e-23 82.4 0.3 2.3 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain CbiG_mid PF11761.8 ORY35218.1 - 3.3e-06 27.1 0.0 3.6 7.8 0.0 3.5 2 1 1 3 3 3 3 Cobalamin biosynthesis central region YflT PF11181.8 ORY35218.1 - 5.2e-05 23.7 2.0 0.1 13.1 1.1 2.8 3 0 0 3 3 3 2 Heat induced stress protein YflT RRM_occluded PF16842.5 ORY35218.1 - 0.00031 20.5 0.0 0.14 12.1 0.0 3.4 3 1 0 3 3 3 1 Occluded RNA-recognition motif RRM_7 PF16367.5 ORY35218.1 - 0.002 18.2 0.2 9.5 6.4 0.0 4.6 4 2 0 4 4 4 1 RNA recognition motif Nup35_RRM_2 PF14605.6 ORY35218.1 - 0.002 18.1 0.5 3.3 7.8 0.0 3.8 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 ORY35218.1 - 0.003 17.2 0.2 4.6 7.0 0.0 3.4 3 0 0 3 3 3 1 Ribonuclease B OB domain Limkain-b1 PF11608.8 ORY35218.1 - 0.036 14.1 1.1 8 6.6 0.2 3.3 3 1 1 4 4 4 0 Limkain b1 RRM_3 PF08777.11 ORY35218.1 - 0.18 11.9 9.9 19 5.4 5.8 3.3 2 1 1 3 3 3 0 RNA binding motif UPF0524 PF15823.5 ORY35218.1 - 0.45 9.9 2.9 6 6.2 0.3 2.2 2 0 0 2 2 2 0 UPF0524 of C3orf70 Usp PF00582.26 ORY35219.1 - 1.1e-22 81.0 0.1 3e-22 79.6 0.1 1.6 1 1 0 1 1 1 1 Universal stress protein family COesterase PF00135.28 ORY35220.1 - 4.5e-98 329.3 0.0 5.5e-98 329.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 ORY35220.1 - 0.0011 18.8 0.1 0.0047 16.8 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY35220.1 - 0.028 13.9 0.1 0.059 12.8 0.1 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Usp PF00582.26 ORY35221.1 - 7.8e-24 84.8 0.1 1.9e-23 83.5 0.1 1.5 1 1 0 1 1 1 1 Universal stress protein family PDZ_assoc PF10600.9 ORY35221.1 - 0.059 14.2 0.0 0.11 13.4 0.0 1.4 1 0 0 1 1 1 0 PDZ-associated domain of NMDA receptors Usp PF00582.26 ORY35222.1 - 2.4e-16 60.5 0.0 4.3e-16 59.7 0.0 1.4 1 1 0 1 1 1 1 Universal stress protein family DUF1611 PF07755.11 ORY35222.1 - 0.13 11.5 0.0 0.53 9.5 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1611_C) P-loop domain Ras PF00071.22 ORY35223.1 - 8.7e-55 184.7 0.1 1e-54 184.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY35223.1 - 1e-21 77.3 0.0 2.1e-21 76.4 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY35223.1 - 3.2e-13 49.5 0.0 3.7e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY35223.1 - 2.2e-06 27.3 0.2 8.7e-05 22.1 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY35223.1 - 8e-05 22.7 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY35223.1 - 0.00021 21.2 0.0 0.0025 17.8 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase ATP_bind_1 PF03029.17 ORY35223.1 - 0.00023 21.0 0.1 0.00039 20.3 0.0 1.5 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 ORY35223.1 - 0.00096 18.7 0.0 0.017 14.7 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 ORY35223.1 - 0.058 13.8 0.1 0.13 12.6 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 ORY35223.1 - 0.087 12.2 0.0 0.36 10.2 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein Usp PF00582.26 ORY35224.1 - 1.7e-29 103.1 0.0 2.2e-29 102.8 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family RBP_receptor PF14752.6 ORY35226.1 - 0.014 14.0 6.5 0.015 13.9 6.5 1.0 1 0 0 1 1 1 0 Retinol binding protein receptor QueT PF06177.11 ORY35226.1 - 0.02 15.2 1.5 0.025 14.9 1.5 1.2 1 0 0 1 1 1 0 QueT transporter Mgm101p PF06420.12 ORY35227.1 - 7.6e-60 201.3 0.4 2.3e-37 128.1 0.0 2.1 1 1 1 2 2 2 2 Mitochondrial genome maintenance MGM101 WSS_VP PF12175.8 ORY35227.1 - 0.098 12.1 0.3 0.14 11.6 0.3 1.2 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP Usp PF00582.26 ORY35228.1 - 6.3e-13 49.4 0.1 1e-12 48.8 0.1 1.3 1 1 0 1 1 1 1 Universal stress protein family Imm31 PF15591.6 ORY35228.1 - 0.039 13.8 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 31 Usp PF00582.26 ORY35229.1 - 1.1e-20 74.6 0.0 1.5e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Usp PF00582.26 ORY35230.1 - 1e-23 84.4 0.0 1.4e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family RBP_receptor PF14752.6 ORY35231.1 - 1e-16 60.7 0.3 1.3e-16 60.3 0.3 1.1 1 0 0 1 1 1 1 Retinol binding protein receptor T2SSI PF02501.17 ORY35231.1 - 0.019 15.1 0.9 0.043 14.0 0.9 1.6 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein I Hist_deacetyl PF00850.19 ORY35232.1 - 4.9e-54 183.9 0.0 6.5e-50 170.3 0.0 2.0 2 0 0 2 2 2 2 Histone deacetylase domain DUF1256 PF06866.11 ORY35232.1 - 0.066 12.6 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) PAC2 PF09754.9 ORY35232.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 PAC2 family Hist_deacetyl PF00850.19 ORY35233.1 - 2.1e-68 231.1 0.0 2.6e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Histone deacetylase domain DUF1256 PF06866.11 ORY35233.1 - 0.16 11.4 0.1 0.38 10.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1256) RBP_receptor PF14752.6 ORY35234.1 - 3e-18 65.7 14.3 2.1e-16 59.6 14.3 2.9 1 1 0 1 1 1 1 Retinol binding protein receptor DUF2315 PF10231.9 ORY35235.1 - 2.1e-19 69.8 2.3 2.6e-19 69.5 2.3 1.1 1 0 0 1 1 1 1 Apoptogenic protein 1 UIM PF02809.20 ORY35236.1 - 9.6 6.4 15.3 0.52 10.4 0.9 3.1 3 0 0 3 3 3 0 Ubiquitin interaction motif B_lectin PF01453.24 ORY35239.1 - 0.028 15.0 0.6 0.58 10.7 0.0 2.3 1 1 1 2 2 2 0 D-mannose binding lectin B_lectin PF01453.24 ORY35240.1 - 4.5e-05 23.9 0.1 9.2e-05 22.9 0.1 1.5 2 0 0 2 2 2 1 D-mannose binding lectin PQQ PF01011.21 ORY35240.1 - 0.0099 15.8 0.2 0.16 12.0 0.0 2.5 2 0 0 2 2 2 1 PQQ enzyme repeat DUF3081 PF11280.8 ORY35240.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3081) SCAI PF12070.8 ORY35241.1 - 1.9e-185 617.8 0.0 2.5e-185 617.4 0.0 1.1 1 0 0 1 1 1 1 Protein SCAI DUF3964 PF13107.6 ORY35241.1 - 0.14 12.6 0.5 0.3 11.5 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3964) FA_desaturase PF00487.24 ORY35242.1 - 3.6e-26 92.6 23.1 3.6e-26 92.6 23.1 1.5 2 0 0 2 2 2 1 Fatty acid desaturase HCO3_cotransp PF00955.21 ORY35242.1 - 0.0051 15.7 0.7 0.0051 15.7 0.7 1.5 1 1 1 2 2 2 1 HCO3- transporter family GAPES3 PF17154.4 ORY35243.1 - 0.011 15.7 0.3 0.088 12.8 0.1 2.3 2 0 0 2 2 2 0 Gammaproteobacterial periplasmic sensor domain Tropomyosin_1 PF12718.7 ORY35243.1 - 0.02 15.1 0.9 0.047 13.8 0.2 1.9 2 0 0 2 2 2 0 Tropomyosin like SlyX PF04102.12 ORY35243.1 - 0.44 11.2 4.5 5.8 7.6 0.2 3.1 3 0 0 3 3 3 0 SlyX Snapin_Pallidin PF14712.6 ORY35243.1 - 0.5 10.8 4.6 4.4 7.8 0.6 2.6 2 0 0 2 2 2 0 Snapin/Pallidin Med9 PF07544.13 ORY35243.1 - 0.64 10.1 4.0 2.1 8.5 0.1 2.8 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 MFS_1 PF07690.16 ORY35244.1 - 6.3e-29 101.0 28.6 9.2e-29 100.5 28.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily FA_hydroxylase PF04116.13 ORY35245.1 - 1.1e-23 84.1 11.6 1.1e-23 84.1 8.9 2.4 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily RhoGAP PF00620.27 ORY35248.1 - 9.1e-09 35.3 0.1 1.9e-08 34.3 0.0 1.5 2 0 0 2 2 2 1 RhoGAP domain GCIP PF13324.6 ORY35249.1 - 0.67 9.5 3.3 20 4.7 3.2 2.2 1 1 0 1 1 1 0 Grap2 and cyclin-D-interacting p450 PF00067.22 ORY35250.1 - 2.3e-30 105.8 1.2 7.8e-23 80.9 0.4 3.0 1 1 0 2 2 2 2 Cytochrome P450 GlcNAc PF11397.8 ORY35251.1 - 3.7e-38 131.9 0.0 3.6e-29 102.3 0.0 2.2 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) 2OG-FeII_Oxy_3 PF13640.6 ORY35251.1 - 2.3e-16 60.4 0.0 4.3e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 ORY35251.1 - 3.6e-11 43.6 0.0 8e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Med20 PF08612.11 ORY35251.1 - 0.19 11.1 0.1 0.48 9.8 0.1 1.7 1 0 0 1 1 1 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex POM121 PF15229.6 ORY35253.1 - 0.04 13.5 1.4 0.058 13.0 0.2 1.8 2 0 0 2 2 2 0 POM121 family PSCyt3 PF07627.11 ORY35254.1 - 0.057 13.7 0.2 2.5 8.4 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1588) Pkinase PF00069.25 ORY35255.1 - 6.5e-63 212.6 5.8 1.7e-55 188.2 0.0 2.3 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY35255.1 - 9.4e-40 136.5 4.3 5.4e-36 124.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase KA1 PF02149.19 ORY35255.1 - 1.1e-10 41.1 0.0 2.7e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Kinase associated domain 1 Pkinase_fungal PF17667.1 ORY35255.1 - 4.6e-05 22.4 0.2 9.5e-05 21.3 0.2 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY35255.1 - 0.00033 20.1 0.2 0.0016 17.8 0.0 2.2 3 1 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 ORY35255.1 - 0.00066 18.7 0.1 0.0015 17.5 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 ORY35255.1 - 0.0057 16.3 7.0 0.0066 16.1 0.0 2.4 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 ORY35255.1 - 0.053 12.9 0.1 0.11 11.8 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Drf_FH1 PF06346.12 ORY35255.1 - 0.054 13.2 13.8 0.12 12.1 13.8 1.5 1 0 0 1 1 1 0 Formin Homology Region 1 NPR3 PF03666.13 ORY35255.1 - 0.89 8.3 6.2 1.8 7.3 6.2 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GH97_C PF14509.6 ORY35255.1 - 3.3 8.0 5.6 3.5 7.9 0.0 3.0 3 1 0 3 3 3 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation RR_TM4-6 PF06459.12 ORY35255.1 - 3.6 7.3 13.0 7 6.4 13.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nucleoporin_N PF08801.11 ORY35257.1 - 0.0053 15.5 0.3 0.0059 15.4 0.3 1.3 1 1 0 1 1 1 1 Nup133 N terminal like GPI-anchored PF10342.9 ORY35257.1 - 0.0065 17.2 0.3 0.0065 17.2 0.3 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3984 PF13136.6 ORY35258.1 - 0.0019 17.7 1.1 0.0023 17.4 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) Arrestin_N PF00339.29 ORY35260.1 - 1.7e-07 31.4 0.1 4.9e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY35260.1 - 0.00011 22.6 2.4 0.004 17.6 0.1 3.2 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain GEN1_C PF18380.1 ORY35260.1 - 0.0047 17.8 1.0 0.0047 17.8 1.0 2.2 3 0 0 3 3 3 1 Holliday junction resolvase Gen1 C-terminal domain MMR_HSR1 PF01926.23 ORY35261.1 - 1.7e-05 24.9 0.5 9.4e-05 22.5 0.2 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 ORY35261.1 - 0.00081 19.9 0.3 0.0043 17.6 0.0 2.1 2 1 0 2 2 2 1 ABC transporter AIG1 PF04548.16 ORY35261.1 - 0.0014 18.0 0.0 0.0045 16.4 0.0 1.8 1 1 1 2 2 2 1 AIG1 family FeoB_N PF02421.18 ORY35261.1 - 0.0016 18.0 0.2 0.0061 16.1 0.1 2.0 2 1 0 2 2 2 1 Ferrous iron transport protein B AAA PF00004.29 ORY35261.1 - 0.0022 18.4 0.7 0.45 10.9 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY35261.1 - 0.022 15.0 0.6 0.5 10.6 0.0 2.5 2 1 1 3 3 3 0 AAA domain Dynamin_N PF00350.23 ORY35261.1 - 0.11 12.5 0.6 11 6.1 0.0 2.9 3 1 0 3 3 3 0 Dynamin family RsgA_GTPase PF03193.16 ORY35261.1 - 0.12 12.2 2.8 0.12 12.2 0.2 2.3 3 1 0 3 3 3 0 RsgA GTPase AAA_16 PF13191.6 ORY35261.1 - 0.14 12.5 1.3 0.82 10.0 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 ORY35261.1 - 0.19 12.2 2.2 1 9.8 2.2 2.0 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ORY35262.1 - 2.3e-07 30.9 0.0 8.5e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 ORY35262.1 - 0.0001 22.9 0.0 0.00022 21.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Dynamin_N PF00350.23 ORY35262.1 - 0.00066 19.8 0.1 0.0099 16.0 0.0 2.5 3 0 0 3 3 3 1 Dynamin family FeoB_N PF02421.18 ORY35262.1 - 0.00079 19.0 0.0 0.002 17.7 0.0 1.8 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_24 PF13479.6 ORY35262.1 - 0.0021 17.8 0.0 0.004 16.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 ORY35262.1 - 0.0028 17.9 0.0 0.0064 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ORY35262.1 - 0.004 17.1 0.0 0.0077 16.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 ORY35262.1 - 0.0049 17.4 0.0 0.013 16.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORY35262.1 - 0.0075 16.5 0.0 0.041 14.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 ORY35262.1 - 0.013 15.4 0.0 0.053 13.4 0.0 2.0 3 0 0 3 3 3 0 NACHT domain Roc PF08477.13 ORY35262.1 - 0.033 14.4 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Spc7 PF08317.11 ORY35262.1 - 0.06 12.2 0.3 0.091 11.6 0.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Arf PF00025.21 ORY35262.1 - 0.075 12.5 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_29 PF13555.6 ORY35262.1 - 0.094 12.5 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY35262.1 - 0.095 13.1 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 ORY35262.1 - 0.11 12.1 0.2 0.11 12.1 0.2 2.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 ORY35262.1 - 0.12 12.5 0.1 0.21 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 ORY35262.1 - 0.16 11.4 0.1 1.7 8.1 0.0 2.4 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.6 ORY35262.1 - 0.32 11.5 2.6 0.62 10.5 0.3 2.2 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ORY35263.1 - 3.3e-07 30.4 0.1 1.5e-06 28.3 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 ORY35263.1 - 7e-05 23.4 0.1 0.00015 22.2 0.1 1.5 1 1 0 1 1 1 1 ABC transporter FeoB_N PF02421.18 ORY35263.1 - 0.00089 18.8 0.0 0.0018 17.8 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ORY35263.1 - 0.0012 18.8 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 ORY35263.1 - 0.0017 18.4 0.0 0.012 15.6 0.0 2.1 2 0 0 2 2 2 1 Dynamin family NACHT PF05729.12 ORY35263.1 - 0.015 15.2 0.0 0.054 13.4 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 ORY35263.1 - 0.017 15.4 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY35263.1 - 0.018 14.7 0.0 0.031 14.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ORY35263.1 - 0.025 14.8 0.0 0.062 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 ORY35263.1 - 0.026 14.8 0.0 0.049 13.8 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 ORY35263.1 - 0.028 14.0 0.3 0.083 12.5 0.1 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 ORY35263.1 - 0.041 13.6 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 ORY35263.1 - 0.088 13.4 0.0 0.14 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 ORY35263.1 - 0.089 12.5 0.4 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 ORY35263.1 - 0.098 13.0 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Arf PF00025.21 ORY35263.1 - 0.1 12.0 0.0 0.27 10.7 0.0 1.6 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_33 PF13671.6 ORY35263.1 - 0.12 12.5 0.1 0.18 12.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain Cep57_CLD_2 PF14197.6 ORY35264.1 - 0.0014 18.7 8.0 0.031 14.4 1.7 2.8 2 1 0 2 2 2 2 Centrosome localisation domain of PPC89 GAS PF13851.6 ORY35264.1 - 0.018 14.4 4.5 0.072 12.4 0.7 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding KELK PF15796.5 ORY35264.1 - 0.18 12.3 7.6 0.64 10.5 0.8 2.7 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase SKA2 PF16740.5 ORY35264.1 - 0.19 11.6 3.9 0.5 10.2 0.5 2.9 2 2 1 3 3 3 0 Spindle and kinetochore-associated protein 2 Tropomyosin_1 PF12718.7 ORY35264.1 - 0.28 11.4 5.8 0.17 12.0 1.1 2.3 2 0 0 2 2 2 0 Tropomyosin like APG6_N PF17675.1 ORY35264.1 - 1.2 9.7 7.8 5.7 7.5 0.7 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region CENP-Q PF13094.6 ORY35264.1 - 1.3 9.2 12.1 0.027 14.7 2.4 2.8 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Csm1_N PF18504.1 ORY35264.1 - 2.6 8.4 6.8 0.92 9.9 1.1 2.5 2 0 0 2 2 2 0 Csm1 N-terminal domain ALIX_LYPXL_bnd PF13949.6 ORY35264.1 - 2.7 7.2 10.2 27 3.9 9.2 2.6 2 1 0 2 2 2 0 ALIX V-shaped domain binding to HIV TMF_DNA_bd PF12329.8 ORY35264.1 - 4.5 7.3 8.7 16 5.6 1.3 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SURF4 PF02077.15 ORY35265.1 - 5.1e-75 252.5 1.9 5.6e-75 252.4 1.9 1.0 1 0 0 1 1 1 1 SURF4 family SURF4 PF02077.15 ORY35266.1 - 6.1e-76 255.5 5.8 8.3e-76 255.1 5.8 1.2 1 0 0 1 1 1 1 SURF4 family Holin_SPP1 PF04688.13 ORY35266.1 - 1.7 8.8 8.2 1.2 9.3 1.9 2.8 2 1 0 2 2 2 0 SPP1 phage holin DUF1673 PF07895.11 ORY35266.1 - 2.4 7.8 6.8 7.7 6.2 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Amidase PF01425.21 ORY35267.1 - 1.5e-48 165.9 6.2 1.3e-47 162.8 4.1 2.3 2 1 0 2 2 2 2 Amidase GPI-anchored PF10342.9 ORY35269.1 - 4.1e-08 33.9 1.4 4.1e-08 33.9 1.4 1.8 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.9 ORY35270.1 - 0.0081 16.9 1.9 0.0081 16.9 1.9 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF473 PF04322.12 ORY35270.1 - 0.13 12.1 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF473) Flu_C_NS1 PF03506.13 ORY35271.1 - 0.025 14.6 0.1 0.026 14.5 0.1 1.1 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Toxin_21 PF08091.11 ORY35271.1 - 0.033 14.1 2.1 0.26 11.3 0.1 2.4 2 0 0 2 2 2 0 Spider insecticidal peptide TPR_12 PF13424.6 ORY35272.1 - 2.3e-163 530.9 37.3 6e-22 77.7 0.1 9.6 1 1 10 11 11 11 11 Tetratricopeptide repeat TPR_10 PF13374.6 ORY35272.1 - 4.6e-158 509.6 11.4 3.2e-15 55.5 0.0 12.1 12 0 0 12 12 12 11 Tetratricopeptide repeat TPR_7 PF13176.6 ORY35272.1 - 1.1e-64 209.8 13.9 8.6e-06 25.4 0.0 11.8 12 0 0 12 12 12 11 Tetratricopeptide repeat TPR_1 PF00515.28 ORY35272.1 - 6.2e-50 165.1 40.8 2.5e-05 23.9 0.0 11.6 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_8 PF13181.6 ORY35272.1 - 1.8e-40 133.7 40.6 0.0006 19.8 0.0 11.5 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_2 PF07719.17 ORY35272.1 - 2.3e-24 83.5 28.8 0.048 13.8 0.0 11.1 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY35272.1 - 2.3e-21 76.6 2.6 4.5e-07 29.6 0.3 4.0 1 1 2 4 4 4 4 MalT-like TPR region TPR_14 PF13428.6 ORY35272.1 - 9.1e-20 69.7 0.0 6.6 7.8 0.0 10.7 6 2 5 11 11 10 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY35272.1 - 3.4e-17 61.5 30.8 0.59 10.6 0.1 11.8 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY35272.1 - 6.7e-17 61.9 7.5 0.48 11.1 0.0 9.6 8 2 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY35272.1 - 3.7e-14 53.0 8.1 0.066 13.7 0.1 7.3 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_4 PF07721.14 ORY35272.1 - 8.6e-14 50.7 0.0 3 8.8 0.0 9.1 10 0 0 10 10 9 1 Tetratricopeptide repeat MIT PF04212.18 ORY35272.1 - 2.5e-10 40.3 13.2 18 5.5 0.1 10.3 6 2 4 10 10 10 0 MIT (microtubule interacting and transport) domain SNAP PF14938.6 ORY35272.1 - 3.3e-06 26.7 0.3 0.38 10.1 0.0 3.7 1 1 0 3 3 3 2 Soluble NSF attachment protein, SNAP TPR_3 PF07720.12 ORY35272.1 - 3.9e-06 26.7 39.1 0.21 11.6 0.0 9.4 10 0 0 10 10 10 4 Tetratricopeptide repeat DUF4488 PF14869.6 ORY35272.1 - 0.00035 20.5 5.9 1.8 8.5 0.1 6.4 3 2 2 5 5 5 1 Domain of unknown function (DUF4488) TPR_6 PF13174.6 ORY35272.1 - 0.022 15.4 19.9 12 6.8 0.0 9.2 10 0 0 10 10 10 0 Tetratricopeptide repeat Rh5 PF18515.1 ORY35272.1 - 0.026 13.8 5.8 20 4.4 0.0 5.3 3 3 3 7 7 7 0 Rh5 coiled-coil domain DUF3887 PF13026.6 ORY35272.1 - 0.042 14.7 3.8 40 5.1 0.0 5.9 5 1 1 6 6 5 0 Protein of unknown function (DUF3887) Galactosyl_T PF01762.21 ORY35272.1 - 0.097 12.5 0.1 59 3.4 0.0 3.9 2 1 3 5 5 5 0 Galactosyltransferase TPR_20 PF14561.6 ORY35272.1 - 0.15 12.4 10.8 47 4.4 0.0 7.7 3 3 7 10 10 10 0 Tetratricopeptide repeat DUF3744 PF12558.8 ORY35272.1 - 0.5 11.2 5.3 39 5.1 0.0 5.2 5 1 0 5 5 4 0 ATP-binding cassette cobalt transporter Glyco_hydro_20 PF00728.22 ORY35937.1 - 3.1e-13 49.9 0.3 1.6e-10 40.9 0.1 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 ORY35937.1 - 5.4e-11 43.3 0.1 9.3e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 ORY35937.1 - 1.4e-08 35.5 0.2 3e-08 34.4 0.1 1.7 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like TPK_B1_binding PF04265.14 ORY35937.1 - 0.0079 15.9 0.0 0.019 14.6 0.0 1.7 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Lactamase_B_2 PF12706.7 ORY35938.1 - 5.1e-22 78.4 0.1 6.5e-22 78.0 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY35938.1 - 1.2e-07 31.9 0.2 2.2e-07 31.1 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 ORY35938.1 - 0.0057 16.1 0.1 0.01 15.3 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Ezh2_MCSS PF18600.1 ORY35938.1 - 0.052 13.2 0.4 0.11 12.1 0.4 1.5 1 0 0 1 1 1 0 MCSS domain Elf1 PF05129.13 ORY35940.1 - 0.39 10.8 1.7 0.78 9.8 1.7 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Zn_ribbon_recom PF13408.6 ORY35940.1 - 5.5 7.6 6.4 0.53 10.8 0.9 2.1 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain SET PF00856.28 ORY35941.1 - 7.4e-10 39.5 0.0 5.7e-09 36.6 0.0 2.2 2 1 0 2 2 2 1 SET domain OPT PF03169.15 ORY35942.1 - 3e-118 396.1 49.8 3.4e-118 395.9 49.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2109 PF09882.9 ORY35942.1 - 1.3 9.1 4.7 0.73 9.9 0.5 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) ABC_membrane PF00664.23 ORY35943.1 - 3.2e-118 394.3 16.6 2.1e-60 204.7 4.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY35943.1 - 4e-68 228.2 1.8 1.3e-34 119.7 0.0 2.7 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 ORY35943.1 - 6.1e-16 58.5 7.8 1.2e-06 28.2 0.0 4.3 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 ORY35943.1 - 5.1e-09 35.5 0.6 0.00028 19.8 0.3 2.6 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 ORY35943.1 - 4.6e-07 30.2 2.5 0.059 13.7 0.1 4.0 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ORY35943.1 - 5.5e-07 30.1 1.8 0.034 14.5 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORY35943.1 - 1.1e-06 28.7 0.0 0.046 13.6 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 ORY35943.1 - 1.7e-06 28.5 3.3 0.041 14.3 0.1 4.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 ORY35943.1 - 1.2e-05 24.9 0.8 0.014 15.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 ORY35943.1 - 4.1e-05 23.4 0.6 0.21 11.3 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA_15 PF13175.6 ORY35943.1 - 0.00014 21.7 0.0 0.07 12.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.6 ORY35943.1 - 0.00022 21.4 3.7 1 9.6 0.5 4.1 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 ORY35943.1 - 0.0003 20.7 0.1 0.3 11.0 0.0 2.9 3 0 0 3 3 2 1 Rad17 P-loop domain AAA_7 PF12775.7 ORY35943.1 - 0.00079 19.0 0.0 0.35 10.4 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 ORY35943.1 - 0.0012 18.1 1.2 0.88 8.8 0.0 3.4 3 1 0 3 3 3 1 Zeta toxin G-alpha PF00503.20 ORY35943.1 - 0.0056 15.9 0.0 0.29 10.2 0.0 2.4 2 1 0 2 2 2 1 G-protein alpha subunit AAA_18 PF13238.6 ORY35943.1 - 0.0066 17.0 0.1 6.1 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 ORY35943.1 - 0.0072 16.3 0.6 3.6 7.6 0.0 3.4 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.18 ORY35943.1 - 0.0088 15.8 1.0 2.2 7.9 0.0 3.3 3 0 0 3 3 3 1 Cytidylate kinase AAA_21 PF13304.6 ORY35943.1 - 0.0094 15.8 0.1 2.9 7.6 0.0 3.4 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 ORY35943.1 - 0.011 15.9 0.0 1.1 9.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORY35943.1 - 0.012 16.0 0.1 9.3 6.7 0.1 2.8 2 1 0 2 2 2 0 RNA helicase DUF815 PF05673.13 ORY35943.1 - 0.017 14.3 0.0 0.68 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 ORY35943.1 - 0.018 14.8 0.0 8.8 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 ORY35943.1 - 0.028 13.3 0.2 4 6.3 0.1 2.9 2 0 0 2 2 2 0 AAA-like domain SRP54 PF00448.22 ORY35943.1 - 0.049 13.3 0.1 7.8 6.1 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 ORY35943.1 - 0.052 13.8 0.1 14 5.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ORY35943.1 - 0.07 12.7 1.2 28 4.2 0.0 3.8 4 0 0 4 4 4 0 AAA domain APS_kinase PF01583.20 ORY35943.1 - 0.091 12.7 0.2 16 5.4 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase IstB_IS21 PF01695.17 ORY35943.1 - 0.11 12.3 1.5 18 5.0 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein ATP_bind_1 PF03029.17 ORY35943.1 - 0.11 12.2 0.4 3.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MoaE PF02391.17 ORY35943.1 - 0.14 12.5 0.5 20 5.5 0.1 2.5 2 0 0 2 2 2 0 MoaE protein MMR_HSR1 PF01926.23 ORY35943.1 - 0.17 11.9 0.9 27 4.9 0.0 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_17 PF13207.6 ORY35943.1 - 0.19 12.1 3.3 20 5.6 0.0 3.5 4 0 0 4 4 3 0 AAA domain AAA_23 PF13476.6 ORY35943.1 - 0.3 11.6 11.1 0.66 10.4 0.1 3.5 3 0 0 3 3 3 0 AAA domain DUF2207 PF09972.9 ORY35943.1 - 2.1 7.0 16.1 0.93 8.2 2.9 3.9 4 1 0 4 4 4 0 Predicted membrane protein (DUF2207) CEP76-C2 PF15627.6 ORY35944.1 - 0.072 12.6 0.0 0.077 12.6 0.0 1.1 1 0 0 1 1 1 0 CEP76 C2 domain Glyco_hydro_18 PF00704.28 ORY35945.1 - 1.3e-75 255.1 3.1 1.3e-75 255.1 3.1 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 DJ-1_PfpI PF01965.24 ORY35946.1 - 9.1e-22 77.6 0.0 2.9e-21 76.0 0.1 1.7 2 0 0 2 2 2 1 DJ-1/PfpI family Crust_neuro_H PF03858.13 ORY35946.1 - 0.013 16.3 0.1 0.048 14.5 0.0 2.1 2 0 0 2 2 2 0 Crustacean neurohormone H Atu4866 PF11512.8 ORY35946.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Agrobacterium tumefaciens protein Atu4866 Sel1 PF08238.12 ORY35947.1 - 5.3e-31 106.4 29.9 2e-05 25.1 0.1 12.0 13 0 0 13 13 13 7 Sel1 repeat TPR_14 PF13428.6 ORY35947.1 - 0.0029 18.3 0.5 73 4.6 0.1 5.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY35947.1 - 0.0047 17.5 8.7 24 5.8 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TipAS PF07739.13 ORY35947.1 - 0.034 14.7 0.1 0.32 11.6 0.0 2.5 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain Ank_2 PF12796.7 ORY35948.1 - 7.5e-10 39.3 12.1 0.0037 17.8 0.1 6.5 5 3 0 6 6 6 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORY35948.1 - 0.0062 16.9 1.5 0.24 11.9 0.0 4.4 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 ORY35948.1 - 0.015 15.6 9.4 0.4 11.1 0.0 6.5 6 1 1 7 7 7 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY35948.1 - 0.021 15.3 7.8 6.2e+02 1.6 0.0 9.5 12 0 0 12 12 12 0 Ankyrin repeat Ank_4 PF13637.6 ORY35948.1 - 0.023 15.3 4.1 1.8 9.2 0.0 5.5 6 1 2 8 8 8 0 Ankyrin repeats (many copies) DUF3447 PF11929.8 ORY35948.1 - 0.033 14.1 1.2 0.3 11.1 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) Acid_PPase PF12689.7 ORY35948.1 - 0.15 11.9 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 Acid Phosphatase F-box-like PF12937.7 ORY35948.1 - 0.16 11.9 1.2 1 9.3 0.2 2.5 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 ORY35948.1 - 0.25 11.2 2.3 2 8.4 0.3 3.1 2 0 0 2 2 2 0 F-box domain Ank_5 PF13857.6 ORY35949.1 - 0.029 14.7 0.0 0.072 13.4 0.0 1.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ras PF00071.22 ORY35950.1 - 2.2e-37 128.2 0.0 2.6e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY35950.1 - 6.9e-13 48.9 0.0 1.1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORY35950.1 - 4.3e-05 23.6 0.0 9.5e-05 22.5 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 ORY35950.1 - 6.3e-05 22.5 0.0 7.6e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY35950.1 - 8.4e-05 22.2 0.0 0.00061 19.4 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain COX5A PF02284.16 ORY35950.1 - 0.0094 15.9 0.0 0.025 14.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va FeoB_N PF02421.18 ORY35950.1 - 0.16 11.5 0.2 2 7.9 0.2 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_membrane PF00664.23 ORY35952.1 - 7.5e-120 399.7 12.8 7.4e-62 209.5 1.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY35952.1 - 5.8e-68 227.7 3.3 2.2e-34 118.9 0.0 2.8 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 ORY35952.1 - 1.2e-16 60.9 7.1 2.2e-07 30.5 0.0 4.4 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY35952.1 - 3.7e-07 30.7 0.3 0.071 13.5 0.2 3.1 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORY35952.1 - 2.8e-06 27.3 0.0 0.049 13.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 ORY35952.1 - 7.1e-06 26.3 1.7 0.047 14.0 0.2 3.6 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 ORY35952.1 - 1.2e-05 25.5 3.6 0.052 13.8 0.3 4.2 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 ORY35952.1 - 1.2e-05 24.3 0.8 0.046 12.5 0.0 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 ORY35952.1 - 0.0001 22.0 0.9 0.1 12.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 ORY35952.1 - 0.00013 21.8 0.2 0.51 10.0 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA PF00004.29 ORY35952.1 - 0.00018 22.0 4.5 0.25 11.8 0.1 4.1 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ORY35952.1 - 0.00038 20.0 0.0 0.56 9.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Zeta_toxin PF06414.12 ORY35952.1 - 0.0011 18.2 0.3 6.2 6.1 0.0 3.4 3 0 0 3 3 3 0 Zeta toxin AAA_15 PF13175.6 ORY35952.1 - 0.0019 18.0 0.1 0.2 11.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Glyoxalase_3 PF13468.6 ORY35952.1 - 0.002 18.3 0.0 0.11 12.6 0.0 2.5 2 0 0 2 2 2 1 Glyoxalase-like domain Rad17 PF03215.15 ORY35952.1 - 0.0033 17.4 0.0 0.25 11.3 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain G-alpha PF00503.20 ORY35952.1 - 0.0095 15.1 0.1 3 6.9 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_5 PF07728.14 ORY35952.1 - 0.012 15.6 0.4 8.9 6.3 0.0 3.3 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 ORY35952.1 - 0.018 14.8 0.8 3.6 7.3 0.0 3.8 6 0 0 6 6 4 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 ORY35952.1 - 0.032 13.4 0.0 3.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AIG1 PF04548.16 ORY35952.1 - 0.034 13.5 0.1 2.5 7.4 0.0 2.6 2 0 0 2 2 2 0 AIG1 family RNA_helicase PF00910.22 ORY35952.1 - 0.041 14.3 0.1 16 5.9 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 ORY35952.1 - 0.045 14.2 5.1 1.9 9.0 0.1 3.2 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.7 ORY35952.1 - 0.048 12.6 0.1 2.4 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain MoaE PF02391.17 ORY35952.1 - 0.055 13.7 0.9 13 6.1 0.1 2.7 2 0 0 2 2 2 0 MoaE protein AAA_24 PF13479.6 ORY35952.1 - 0.06 13.1 0.1 9.4 5.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ORY35952.1 - 0.064 12.8 0.2 16 5.0 0.0 3.5 4 0 0 4 4 3 0 AAA domain KorB PF08535.10 ORY35952.1 - 0.099 12.7 0.1 41 4.3 0.0 3.5 3 0 0 3 3 3 0 KorB domain PRK PF00485.18 ORY35952.1 - 0.11 12.2 0.2 7.9 6.2 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 ORY35952.1 - 0.15 12.2 0.4 9.9 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ORY35952.1 - 0.41 10.4 2.5 39 3.9 0.1 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein Hydrolase PF00702.26 ORY35953.1 - 3e-07 30.9 0.0 3.6e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY35953.1 - 0.00014 22.0 0.1 0.00018 21.6 0.1 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY35953.1 - 0.001 19.1 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like TFA2_Winged_2 PF18121.1 ORY35954.1 - 0.17 11.6 0.7 0.89 9.3 0.1 2.5 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 Ice_nucleation PF00818.17 ORY35954.1 - 6.7 7.0 10.3 5.8 7.2 2.3 3.7 2 0 0 2 2 2 0 Ice nucleation protein repeat SNF2_N PF00176.23 ORY35955.1 - 3.6e-67 226.6 0.0 5.9e-67 225.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY35955.1 - 6.1e-16 58.8 0.0 1.7e-15 57.3 0.0 1.8 2 0 0 2 2 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 ORY35955.1 - 2.1e-08 34.0 1.8 2.1e-08 34.0 1.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger ResIII PF04851.15 ORY35955.1 - 3.8e-08 33.5 0.0 7.3e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 ORY35955.1 - 5.3e-08 32.6 3.4 5.3e-08 32.6 3.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY35955.1 - 9.5e-08 32.1 4.2 2.7e-07 30.6 4.2 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 ORY35955.1 - 7.7e-07 28.9 7.5 1.7e-06 27.8 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY35955.1 - 1.9e-06 28.1 7.6 5e-06 26.7 7.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 ORY35955.1 - 8.8e-06 25.6 6.1 1.9e-05 24.5 6.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY35955.1 - 4.2e-05 23.3 7.0 0.00013 21.7 7.0 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY35955.1 - 0.00036 20.3 6.3 0.0018 18.1 6.3 2.1 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 TEBP_beta PF07404.11 ORY35955.1 - 0.0024 17.3 0.5 0.0041 16.5 0.5 1.3 1 0 0 1 1 1 1 Telomere-binding protein beta subunit (TEBP beta) SWI2_SNF2 PF18766.1 ORY35955.1 - 0.0058 16.3 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Zn_Tnp_IS91 PF14319.6 ORY35955.1 - 0.077 13.0 0.3 0.21 11.6 0.3 1.7 1 0 0 1 1 1 0 Transposase zinc-binding domain zf-Nse PF11789.8 ORY35955.1 - 0.11 12.3 2.4 0.36 10.7 2.4 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 ORY35955.1 - 0.15 12.4 4.7 0.5 10.7 4.7 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 ORY35955.1 - 0.34 10.8 1.6 0.97 9.4 1.6 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1272 PF06906.11 ORY35955.1 - 2.4 8.3 5.1 2.7 8.1 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Yippee-Mis18 PF03226.14 ORY35957.1 - 4.3 7.6 9.8 5.1 7.4 1.2 3.1 1 1 2 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RibD_C PF01872.17 ORY35958.1 - 1.1e-27 97.1 0.0 1.3e-27 96.9 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain eIF-3c_N PF05470.12 ORY35959.1 - 5.3e-151 503.9 19.5 1.5e-134 449.6 0.7 2.7 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 ORY35959.1 - 5.1e-09 36.6 0.0 4.2e-08 33.6 0.0 2.6 2 0 0 2 2 2 1 PCI domain COG4 PF08318.12 ORY35960.1 - 1.3e-77 261.2 0.8 2.8e-77 260.1 0.2 1.9 2 0 0 2 2 2 1 COG4 transport protein B2 PF11473.8 ORY35960.1 - 0.022 14.5 0.2 0.096 12.5 0.1 2.2 2 0 0 2 2 2 0 RNA binding protein B2 DUF4226 PF10774.9 ORY35960.1 - 6 7.2 8.0 3.9 7.8 2.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4226) NMD3 PF04981.13 ORY35962.1 - 1.1e-82 277.2 4.3 1.7e-82 276.6 4.3 1.3 1 0 0 1 1 1 1 NMD3 family Poty_coat PF00767.18 ORY35962.1 - 0.026 14.1 0.3 0.11 12.0 0.0 1.9 1 1 0 2 2 2 0 Potyvirus coat protein DZR PF12773.7 ORY35962.1 - 0.52 10.4 7.3 44 4.2 7.3 2.9 1 1 0 1 1 1 0 Double zinc ribbon DUF35_N PF12172.8 ORY35962.1 - 1.5 8.8 8.7 1.4 8.9 0.2 3.2 3 0 0 3 3 3 0 Rubredoxin-like zinc ribbon domain (DUF35_N) HD PF01966.22 ORY35966.1 - 3.6e-07 30.4 0.1 1e-06 29.0 0.1 1.8 1 0 0 1 1 1 1 HD domain 2OG-FeII_Oxy_2 PF13532.6 ORY35967.1 - 7.4e-06 26.3 0.0 1.2e-05 25.6 0.0 1.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Ribosomal_L7Ae PF01248.26 ORY35968.1 - 2.1e-23 81.8 0.0 2.7e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family MFS_1 PF07690.16 ORY35969.1 - 4.7e-29 101.4 36.3 6.7e-29 100.9 36.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily PHO4 PF01384.20 ORY35970.1 - 1.2e-103 346.7 20.9 1.4e-103 346.5 20.9 1.0 1 0 0 1 1 1 1 Phosphate transporter family PHO4 PF01384.20 ORY35971.1 - 5.5e-95 318.3 18.6 7.1e-95 317.9 18.6 1.1 1 0 0 1 1 1 1 Phosphate transporter family PHO4 PF01384.20 ORY35972.1 - 1.4e-98 330.0 18.7 1.7e-98 329.8 18.7 1.0 1 0 0 1 1 1 1 Phosphate transporter family PHO4 PF01384.20 ORY35973.1 - 3.2e-71 240.1 11.9 7.5e-56 189.6 0.2 2.1 1 1 1 2 2 2 2 Phosphate transporter family MRP-S28 PF10213.9 ORY35974.1 - 3.4e-11 43.7 0.1 4.6e-11 43.2 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DNA_topoisoIV PF00521.20 ORY35975.1 - 3.8e-128 428.0 0.0 6.4e-128 427.3 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 ORY35975.1 - 1.4e-50 170.9 1.1 1.4e-50 170.9 1.1 2.7 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 ORY35975.1 - 3.7e-25 88.4 0.2 1.1e-24 86.9 0.2 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 ORY35975.1 - 9.5e-15 55.1 0.0 2.3e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 ORY35975.1 - 1.9e-07 31.2 0.0 9.5e-07 29.0 0.0 2.3 1 0 0 1 1 1 1 Toprim domain PulG PF11773.8 ORY35975.1 - 0.067 13.0 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin HlyU PF10115.9 ORY35975.1 - 0.08 13.0 0.0 0.44 10.6 0.0 2.3 1 0 0 1 1 1 0 Transcriptional activator HlyU FA_desaturase PF00487.24 ORY35976.1 - 5.6e-20 72.2 30.4 1.1e-19 71.3 26.3 2.4 1 1 1 2 2 2 1 Fatty acid desaturase DUF2080 PF09853.9 ORY35976.1 - 0.14 11.9 0.0 0.47 10.2 0.0 1.9 2 0 0 2 2 2 0 Putative transposon-encoded protein (DUF2080) HMGL-like PF00682.19 ORY35977.1 - 4.6e-62 210.0 2.5 5.9e-31 108.0 0.1 2.4 1 1 1 2 2 2 2 HMGL-like FliG_N PF14842.6 ORY35977.1 - 0.11 13.1 0.0 0.27 11.8 0.0 1.6 1 0 0 1 1 1 0 FliG N-terminal domain Galactosyl_T PF01762.21 ORY35978.1 - 0.0024 17.7 0.0 0.0038 17.1 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase DUF1691 PF07950.11 ORY35979.1 - 4.7e-08 33.7 3.4 0.00028 21.6 0.3 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1691) Glyco_hydro_38C PF07748.13 ORY35980.1 - 2.8e-41 141.9 0.0 4.8e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro38C2 PF17677.1 ORY35980.1 - 4.9e-10 39.4 0.0 1.1e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_38N PF01074.22 ORY35981.1 - 1.6e-80 270.6 0.7 3.1e-80 269.6 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 ORY35981.1 - 5.4e-28 97.0 0.0 1e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 ORY35981.1 - 8.4e-09 35.8 0.0 1.5e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro_57 PF03065.15 ORY35981.1 - 0.0012 18.2 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Glyco_hydro_38N PF01074.22 ORY35982.1 - 1.7e-80 270.5 0.3 2.8e-80 269.8 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 ORY35982.1 - 2.2e-52 178.2 0.0 3.7e-52 177.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 ORY35982.1 - 8.7e-27 93.1 0.0 1.6e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 ORY35982.1 - 1.7e-09 37.7 0.0 5.2e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 ORY35982.1 - 0.0021 17.3 0.1 0.0038 16.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 PHO4 PF01384.20 ORY35983.1 - 6.6e-103 344.3 22.1 7.9e-103 344.0 22.1 1.1 1 0 0 1 1 1 1 Phosphate transporter family Glyco_hydro_38N PF01074.22 ORY35984.1 - 1e-83 281.1 0.4 2.4e-83 279.8 0.4 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 ORY35984.1 - 4.1e-53 180.6 0.0 6.6e-53 179.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 ORY35984.1 - 1.5e-25 89.1 0.0 3.2e-25 88.1 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 ORY35984.1 - 8.5e-08 32.2 0.0 2.4e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 ORY35984.1 - 0.00067 18.9 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 ECH_1 PF00378.20 ORY35985.1 - 1.1e-05 24.9 0.0 1.3e-05 24.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Galactosyl_T PF01762.21 ORY35986.1 - 0.031 14.1 0.0 0.33 10.7 0.0 2.3 1 1 0 1 1 1 0 Galactosyltransferase Mg_trans_NIPA PF05653.14 ORY35987.1 - 2.7e-80 269.6 20.4 3.3e-80 269.4 20.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORY35987.1 - 7.2e-06 26.2 6.5 7.2e-06 26.2 6.5 4.1 2 2 1 3 3 3 1 EamA-like transporter family Epimerase PF01370.21 ORY35993.1 - 3.4e-20 72.5 0.1 5.6e-20 71.8 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY35993.1 - 1.3e-19 70.3 0.0 1.7e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 ORY35993.1 - 1.3e-13 51.0 0.0 3.2e-13 49.8 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ORY35993.1 - 7e-13 48.9 0.0 1e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ORY35993.1 - 3.1e-12 46.2 0.0 8.2e-11 41.6 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 ORY35993.1 - 5.8e-09 35.8 0.2 9.6e-09 35.1 0.2 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 ORY35993.1 - 7.4e-07 28.6 0.0 1.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 ORY35993.1 - 3.8e-06 26.9 0.1 7.3e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 ORY35993.1 - 1.2e-05 24.9 0.1 0.00011 21.7 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 ORY35993.1 - 0.0021 17.2 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain COX6A PF02046.15 ORY35994.1 - 1.3e-14 54.6 0.6 1.6e-14 54.3 0.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa DUF1336 PF07059.12 ORY35994.1 - 0.13 12.3 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1336) Glyco_trans_2_3 PF13632.6 ORY35995.1 - 5.5e-23 81.9 5.1 5.5e-23 81.9 5.1 1.7 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY35995.1 - 7.8e-14 52.1 0.3 1.4e-13 51.2 0.3 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 ORY35995.1 - 0.095 13.2 0.6 0.3 11.6 0.6 1.8 1 1 0 1 1 1 0 Glycosyl transferase family 2 Pkinase PF00069.25 ORY35996.1 - 2.7e-61 207.3 0.6 3.8e-61 206.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY35996.1 - 3e-30 105.4 0.0 5.8e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 ORY35996.1 - 7.6e-14 51.3 23.3 5e-07 29.5 7.4 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 ORY35996.1 - 1.5e-09 38.4 0.4 4.2e-09 37.0 0.4 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain HR1 PF02185.16 ORY35996.1 - 1.1e-07 31.8 5.2 4.3e-07 29.9 1.7 4.5 4 1 1 5 5 5 2 Hr1 repeat Haspin_kinase PF12330.8 ORY35996.1 - 0.0003 19.9 0.9 0.00048 19.2 0.1 1.7 2 0 0 2 2 2 1 Haspin like kinase domain PHD PF00628.29 ORY35996.1 - 0.17 11.8 22.1 0.16 11.9 6.9 2.6 2 0 0 2 2 2 0 PHD-finger Fer4_9 PF13187.6 ORY35996.1 - 0.34 11.1 13.3 1.1 9.5 12.0 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Presenilin PF01080.17 ORY35996.1 - 2.5 6.8 7.6 4.6 5.9 7.6 1.3 1 0 0 1 1 1 0 Presenilin Galactosyl_T PF01762.21 ORY35997.1 - 0.0078 16.1 0.0 0.88 9.4 0.0 2.7 1 1 1 2 2 2 2 Galactosyltransferase Fringe PF02434.16 ORY35997.1 - 0.052 13.0 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 Fringe-like CFEM PF05730.11 ORY35998.1 - 0.07 13.2 2.4 0.13 12.3 2.4 1.5 1 0 0 1 1 1 0 CFEM domain DUF3682 PF12446.8 ORY35998.1 - 0.17 12.3 5.5 0.33 11.4 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DNA_pol_phi PF04931.13 ORY35999.1 - 0.02 13.0 24.6 0.024 12.8 24.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi CNDH2_C PF16858.5 ORY35999.1 - 0.023 14.6 6.4 0.024 14.5 6.4 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term BUD22 PF09073.10 ORY35999.1 - 0.033 13.5 16.5 0.039 13.3 16.5 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 ORY35999.1 - 0.043 13.2 21.1 0.051 13.0 21.1 1.1 1 0 0 1 1 1 0 SDA1 Cnd2 PF05786.14 ORY35999.1 - 0.061 12.0 11.0 0.065 11.9 11.0 1.0 1 0 0 1 1 1 0 Condensin complex subunit 2 Nop14 PF04147.12 ORY35999.1 - 0.064 11.5 21.8 0.073 11.3 21.8 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 ORY35999.1 - 0.087 11.1 14.1 0.096 11.0 14.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 ORY35999.1 - 0.1 11.0 17.3 0.12 10.8 17.3 1.0 1 0 0 1 1 1 0 Mpp10 protein Zip PF02535.22 ORY35999.1 - 0.11 11.6 1.7 0.14 11.3 1.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Tim54 PF11711.8 ORY35999.1 - 0.15 10.8 2.3 0.2 10.4 2.3 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF913 PF06025.12 ORY35999.1 - 0.16 10.9 4.2 0.21 10.5 4.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) TFIIA PF03153.13 ORY35999.1 - 0.2 11.6 15.8 0.24 11.4 15.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRN3 PF05327.11 ORY35999.1 - 0.22 10.0 15.7 0.25 9.8 15.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Osteopontin PF00865.18 ORY35999.1 - 0.31 10.5 21.3 0.4 10.1 21.3 1.1 1 0 0 1 1 1 0 Osteopontin PPP4R2 PF09184.11 ORY35999.1 - 0.46 10.0 19.3 0.55 9.8 19.3 1.1 1 0 0 1 1 1 0 PPP4R2 SAPS PF04499.15 ORY35999.1 - 0.48 9.2 11.2 0.59 8.9 11.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sporozoite_P67 PF05642.11 ORY35999.1 - 0.6 8.1 8.7 0.81 7.7 8.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CobT PF06213.12 ORY35999.1 - 0.64 9.4 22.1 0.82 9.0 22.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Paf1 PF03985.13 ORY35999.1 - 0.67 8.9 15.5 0.87 8.5 15.5 1.1 1 0 0 1 1 1 0 Paf1 DUF2722 PF10846.8 ORY35999.1 - 0.89 8.4 11.4 1 8.2 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 ORY35999.1 - 1.3 7.7 5.6 1.4 7.6 5.6 1.1 1 0 0 1 1 1 0 Presenilin Vfa1 PF08432.10 ORY35999.1 - 1.5 9.1 11.3 2.2 8.6 11.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Smg8_Smg9 PF10220.9 ORY35999.1 - 1.7 6.8 5.2 1.8 6.7 5.2 1.0 1 0 0 1 1 1 0 Smg8_Smg9 eIF-3c_N PF05470.12 ORY35999.1 - 3.1 6.0 11.3 3.7 5.7 11.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Rhabdo_ncap PF00945.18 ORY35999.1 - 7 5.4 8.4 9.9 4.9 8.4 1.3 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Pes-10 PF07149.11 ORY35999.1 - 8.6 5.3 16.9 12 4.8 16.9 1.2 1 0 0 1 1 1 0 Pes-10 DUF2457 PF10446.9 ORY35999.1 - 9.1 5.3 30.9 12 4.9 30.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Gti1_Pac2 PF09729.9 ORY36000.1 - 1e-24 87.6 0.1 1.6e-20 74.0 0.0 2.6 2 1 1 3 3 3 2 Gti1/Pac2 family TrmO_C PF18389.1 ORY36000.1 - 0.57 10.3 3.9 0.56 10.4 2.2 1.8 2 0 0 2 2 2 0 TrmO C-terminal domain ABC_tran PF00005.27 ORY36001.1 - 7.4e-28 97.8 0.0 1.8e-27 96.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 ORY36001.1 - 1.2e-18 67.4 23.5 1.2e-18 67.4 23.5 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 ORY36001.1 - 5.8e-16 59.2 0.6 5.2e-10 39.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY36001.1 - 2.3e-05 24.0 0.0 0.00022 20.7 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORY36001.1 - 0.0024 18.4 0.0 0.0053 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 ORY36001.1 - 0.0034 17.2 0.2 0.34 10.6 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_30 PF13604.6 ORY36001.1 - 0.019 14.7 0.1 0.13 12.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ORY36001.1 - 0.034 14.5 0.1 0.35 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.6 ORY36001.1 - 0.065 11.9 0.0 1.3 7.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ORY36001.1 - 0.22 11.3 1.1 0.38 10.5 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 ORY36002.1 - 8.1e-26 91.2 0.0 1.3e-25 90.5 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 ORY36002.1 - 8.6e-26 90.9 20.2 1.2e-25 90.3 20.2 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 ORY36002.1 - 5.3e-10 39.6 0.0 8.4e-07 29.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 ORY36002.1 - 0.00039 19.9 21.8 0.00078 18.9 21.8 1.5 1 0 0 1 1 1 1 ABC-2 type transporter AAA_29 PF13555.6 ORY36002.1 - 0.014 15.1 0.2 0.032 14.0 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY36002.1 - 0.03 14.2 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase DUF2705 PF10920.8 ORY36002.1 - 0.046 13.0 9.2 0.086 12.1 9.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2705) AAA_15 PF13175.6 ORY36002.1 - 0.056 13.1 0.0 9.8 5.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.19 ORY36002.1 - 0.059 12.8 0.0 7 6.0 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DLIC PF05783.11 ORY36002.1 - 0.063 12.1 0.0 0.089 11.6 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) VP_N-CPKC PF11475.8 ORY36004.1 - 0.066 13.1 0.2 0.17 11.8 0.2 1.7 1 0 0 1 1 1 0 Virion protein N terminal domain TB2_DP1_HVA22 PF03134.19 ORY36005.1 - 4.2e-16 58.6 2.6 4.2e-16 58.6 2.6 1.8 2 0 0 2 2 2 1 TB2/DP1, HVA22 family TB2_DP1_HVA22 PF03134.19 ORY36006.1 - 5.3e-20 71.1 2.4 5.3e-20 71.1 2.4 1.8 2 0 0 2 2 2 1 TB2/DP1, HVA22 family TMEM208_SND2 PF05620.11 ORY36006.1 - 0.31 10.8 4.3 1.6 8.4 0.4 2.3 2 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 DUF4870 PF09685.10 ORY36006.1 - 5.7 7.1 12.4 8.3 6.6 4.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4870) LRR_8 PF13855.6 ORY36007.1 - 8.4e-14 51.1 3.3 5.3e-07 29.3 0.0 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY36007.1 - 1.1e-07 32.0 10.9 0.00019 21.8 3.8 4.0 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) F-box PF00646.33 ORY36007.1 - 6.1e-07 29.2 0.7 1.7e-06 27.7 0.7 1.8 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.33 ORY36007.1 - 0.00052 20.2 10.0 2.1 9.2 0.6 5.6 5 1 1 6 6 6 2 Leucine Rich Repeat F-box-like PF12937.7 ORY36007.1 - 0.00078 19.3 0.3 0.0024 17.7 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORY36007.1 - 0.034 14.0 0.1 0.058 13.3 0.1 1.4 1 0 0 1 1 1 0 F-box DUF4881 PF16222.5 ORY36008.1 - 0.068 13.0 0.8 0.13 12.1 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4881) Glyco_transf_34 PF05637.12 ORY36009.1 - 1.3e-15 57.8 1.7 1.7e-13 50.9 1.7 2.5 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family ABC_membrane PF00664.23 ORY36010.1 - 1.8e-61 208.2 22.0 2.3e-31 109.5 11.0 3.6 3 1 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY36010.1 - 2.2e-51 174.0 0.3 5.3e-28 98.2 0.2 2.9 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 ORY36010.1 - 2.6e-07 30.3 1.8 0.015 14.7 0.1 3.9 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY36010.1 - 3.6e-06 27.0 0.3 0.092 12.8 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 ORY36010.1 - 4.4e-06 27.3 0.2 0.0011 19.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ORY36010.1 - 5.5e-06 26.4 0.3 0.0049 16.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 ORY36010.1 - 1e-05 25.2 0.4 0.028 14.2 0.0 3.3 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 ORY36010.1 - 1.1e-05 25.4 3.7 0.0027 17.6 0.0 3.5 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORY36010.1 - 2.8e-05 24.6 0.7 0.013 15.9 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 ORY36010.1 - 0.0027 17.8 1.2 2.6 8.1 0.1 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_7 PF12775.7 ORY36010.1 - 0.0033 17.0 0.2 0.39 10.2 0.0 2.8 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 ORY36010.1 - 0.0041 17.4 0.1 0.23 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 ORY36010.1 - 0.0045 17.2 0.1 2.9 8.2 0.0 3.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 ORY36010.1 - 0.0072 16.4 1.3 0.09 12.8 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_30 PF13604.6 ORY36010.1 - 0.017 14.9 1.5 0.12 12.1 0.1 2.6 3 0 0 3 3 3 0 AAA domain Adeno_IVa2 PF02456.15 ORY36010.1 - 0.018 13.8 0.2 0.054 12.3 0.0 1.7 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_25 PF13481.6 ORY36010.1 - 0.023 14.3 0.1 0.94 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ORY36010.1 - 0.043 13.5 0.1 21 4.8 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein T2SSE PF00437.20 ORY36010.1 - 0.046 12.8 0.4 0.19 10.7 0.1 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 ORY36010.1 - 0.055 12.8 1.6 0.78 9.1 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_15 PF13175.6 ORY36010.1 - 0.056 13.1 0.1 0.14 11.8 0.0 1.7 2 0 0 2 2 1 0 AAA ATPase domain NACHT PF05729.12 ORY36010.1 - 0.057 13.3 0.2 0.29 11.0 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 ORY36010.1 - 0.082 13.5 0.2 1.4 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.21 ORY36010.1 - 0.086 12.5 0.3 0.44 10.2 0.0 2.1 2 0 0 2 2 2 0 Guanylate kinase Zeta_toxin PF06414.12 ORY36010.1 - 0.091 12.0 0.7 2.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NAD_binding_8 PF13450.6 ORY36010.1 - 0.1 12.8 0.6 0.81 10.0 0.1 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain cobW PF02492.19 ORY36010.1 - 0.14 11.7 0.9 0.51 9.9 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.21 ORY36010.1 - 0.14 11.5 0.0 11 5.3 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 ORY36010.1 - 0.16 11.1 0.2 8.6 5.5 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain RNA_helicase PF00910.22 ORY36010.1 - 0.19 12.1 0.2 7.1 7.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Myc_N PF01056.18 ORY36010.1 - 0.35 10.7 1.1 0.45 10.3 0.0 1.6 2 0 0 2 2 1 0 Myc amino-terminal region AAA_33 PF13671.6 ORY36010.1 - 0.36 11.0 1.0 2.8 8.1 0.0 2.6 3 0 0 3 3 2 0 AAA domain DUF4498 PF14926.6 ORY36014.1 - 2.5e-86 289.0 0.2 3.2e-86 288.7 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4498) LRR_4 PF12799.7 ORY36015.1 - 1.2e-14 54.2 10.8 0.0045 17.4 2.5 4.7 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY36015.1 - 3.9e-09 36.1 14.7 2.3e-05 24.1 3.1 4.4 3 1 1 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 ORY36015.1 - 0.0024 17.8 12.1 0.65 10.2 0.3 5.8 6 0 0 6 6 6 1 Leucine Rich repeat KinB_sensor PF16767.5 ORY36015.1 - 0.093 13.2 0.1 0.093 13.2 0.1 2.7 3 0 0 3 3 3 0 Sensor domain of alginate biosynthesis sensor protein KinB SCIMP PF15050.6 ORY36015.1 - 0.22 12.0 1.2 0.96 9.9 1.2 2.1 1 0 0 1 1 1 0 SCIMP protein LRR_1 PF00560.33 ORY36015.1 - 0.57 10.9 10.7 4.4 8.2 0.1 5.9 7 0 0 7 7 7 0 Leucine Rich Repeat DUF3439 PF11921.8 ORY36016.1 - 0.12 12.4 12.1 0.29 11.1 12.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 ORY36016.1 - 0.16 10.1 17.3 0.25 9.5 17.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ribosomal_L30_N PF08079.12 ORY36017.1 - 5.3e-29 100.3 14.6 5.3e-29 100.3 14.6 2.0 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 ORY36017.1 - 3.9e-20 71.5 0.8 1.1e-19 70.1 0.8 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Chordopox_G3 PF06129.12 ORY36017.1 - 0.041 14.6 0.2 0.073 13.8 0.2 1.5 1 0 0 1 1 1 0 Chordopoxvirus G3 protein Mcm10 PF09332.11 ORY36017.1 - 0.22 10.9 5.0 0.3 10.5 5.0 1.1 1 0 0 1 1 1 0 Mcm10 replication factor Consortin_C PF15281.6 ORY36017.1 - 0.28 11.2 1.6 0.45 10.5 1.6 1.3 1 0 0 1 1 1 0 Consortin C-terminus NDK PF00334.19 ORY36018.1 - 2.7e-35 121.3 0.0 3.9e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase ADH_N PF08240.12 ORY36019.1 - 1e-24 86.5 5.6 2e-24 85.6 5.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY36019.1 - 2.4e-22 79.3 0.1 5.6e-22 78.1 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORY36019.1 - 7e-08 32.0 0.0 1.3e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORY36019.1 - 7.2e-06 25.5 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 ORY36019.1 - 0.00042 21.4 0.0 0.00081 20.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.15 ORY36019.1 - 0.00053 20.2 0.0 0.00097 19.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 ORY36019.1 - 0.018 14.9 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 ORY36019.1 - 0.038 14.5 0.1 0.08 13.5 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 ORY36019.1 - 0.048 14.1 0.0 0.091 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ADH_N PF08240.12 ORY36020.1 - 6.6e-25 87.1 6.2 1.3e-24 86.2 6.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY36020.1 - 5.2e-22 78.2 0.1 4.4e-21 75.2 0.0 2.4 3 0 0 3 3 3 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 ORY36020.1 - 1.1e-07 31.4 0.9 1.6e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 ORY36020.1 - 6.6e-06 25.6 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 ORY36020.1 - 0.00025 21.3 0.0 0.00047 20.3 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N_2 PF13602.6 ORY36020.1 - 0.00064 20.8 0.0 0.0011 20.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 3HCDH_N PF02737.18 ORY36020.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ORY36020.1 - 0.02 15.0 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 ORY36020.1 - 0.039 14.5 0.1 0.08 13.5 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 ORY36020.1 - 0.044 14.4 0.1 0.3 11.7 0.1 2.2 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 ORY36020.1 - 0.061 13.8 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Methyltransf_25 PF13649.6 ORY36020.1 - 0.061 14.0 0.1 0.19 12.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 ORY36020.1 - 0.062 14.0 0.0 0.14 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 ORY36022.1 - 4.6e-58 196.7 0.0 1.1e-57 195.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY36022.1 - 6.9e-38 130.4 0.0 1.1e-37 129.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 ORY36022.1 - 2.4e-30 105.7 0.0 2.4e-30 105.7 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3543) APH PF01636.23 ORY36022.1 - 0.00064 19.7 0.1 0.0037 17.2 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family MIT PF04212.18 ORY36022.1 - 0.13 12.4 0.4 1.5 9.0 0.1 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain CEP209_CC5 PF16574.5 ORY36023.1 - 0.0071 16.5 17.8 0.11 12.6 3.6 2.3 1 1 1 2 2 2 2 Coiled-coil region of centrosome protein CE290 DivIVA PF05103.13 ORY36023.1 - 0.015 15.4 8.1 0.015 15.4 8.1 2.7 1 1 0 2 2 2 0 DivIVA protein BRE1 PF08647.11 ORY36023.1 - 0.042 13.9 21.5 0.099 12.7 1.9 3.2 3 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase Band_7 PF01145.25 ORY36023.1 - 0.07 13.1 3.9 0.17 11.9 3.9 1.8 1 1 0 1 1 1 0 SPFH domain / Band 7 family Spc7 PF08317.11 ORY36023.1 - 1.4 7.7 25.4 0.85 8.4 19.0 2.4 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF3338 PF11819.8 ORY36023.1 - 2.3 8.2 11.5 0.7 9.9 7.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3338) Mt_ATP-synt_D PF05873.12 ORY36023.1 - 2.4 8.0 13.3 0.095 12.5 4.2 2.7 2 1 1 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) MRP-S23 PF10484.9 ORY36023.1 - 2.6 8.3 6.9 0.34 11.2 2.0 2.0 2 1 1 3 3 3 0 Mitochondrial ribosomal protein S23 SlyX PF04102.12 ORY36023.1 - 2.7 8.7 22.8 0.31 11.7 3.7 4.1 2 1 3 5 5 5 0 SlyX Rho_Binding PF08912.11 ORY36023.1 - 2.7 8.9 20.2 0.15 12.9 4.5 3.5 3 1 0 4 4 3 0 Rho Binding IZUMO PF15005.6 ORY36023.1 - 7.1 7.1 13.0 11 6.6 7.1 2.4 1 1 2 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated TMF_DNA_bd PF12329.8 ORY36023.1 - 7.3 6.7 24.8 0.5 10.4 7.7 3.7 4 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding Sigma54_AID PF00309.20 ORY36023.1 - 7.4 6.5 13.7 2.8 7.9 0.3 3.6 4 0 0 4 4 4 0 Sigma-54 factor, Activator interacting domain (AID) AAA PF00004.29 ORY36025.1 - 0.11 12.9 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY36026.1 - 0.058 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ResIII PF04851.15 ORY36026.1 - 0.064 13.3 1.4 0.34 10.9 0.0 2.3 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 ORY36026.1 - 0.17 12.3 0.0 0.39 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain zf-CCHC PF00098.23 ORY36053.1 - 0.47 10.6 15.1 0.67 10.1 1.1 4.6 4 0 0 4 4 4 0 Zinc knuckle SecA_DEAD PF07517.14 ORY36103.1 - 4.3e-32 111.6 0.0 1.1e-31 110.2 0.0 1.7 1 0 0 1 1 1 1 SecA DEAD-like domain DEAD PF00270.29 ORY36103.1 - 1.3e-05 25.1 0.0 5.7e-05 23.0 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ORY36103.1 - 6.2e-05 23.1 0.0 0.0002 21.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_PP_bind PF01043.20 ORY36103.1 - 0.0013 19.3 0.0 0.0067 17.1 0.0 2.3 1 0 0 1 1 1 1 SecA preprotein cross-linking domain SMBP PF16785.5 ORY36103.1 - 0.42 10.8 3.3 0.37 11.0 0.1 2.5 2 0 0 2 2 2 0 Small metal-binding protein DUF4778 PF16008.5 ORY36104.1 - 1.4 8.9 20.2 2.2 8.3 20.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Hid1 PF12722.7 ORY36104.1 - 5 5.1 18.8 6 4.9 18.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dynamin_N PF00350.23 ORY36105.1 - 3.6e-17 62.9 0.0 8.5e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 ORY36105.1 - 6.1e-11 42.4 0.0 4.3e-10 39.7 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY36105.1 - 1.6e-06 27.8 0.0 0.00018 21.1 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Roc PF08477.13 ORY36105.1 - 1.8e-06 28.2 0.1 0.054 13.7 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY36105.1 - 1.5e-05 24.6 0.2 0.00019 20.9 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY36105.1 - 0.0013 18.2 0.1 0.031 13.6 0.0 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AIG1 PF04548.16 ORY36105.1 - 0.014 14.7 0.3 0.48 9.7 0.1 2.5 2 0 0 2 2 2 0 AIG1 family Dynamin_N PF00350.23 ORY36106.1 - 5e-14 52.7 0.2 5e-14 52.7 0.2 1.7 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 ORY36106.1 - 1.1e-08 35.1 0.1 6.2e-08 32.7 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY36106.1 - 3.4e-07 30.0 2.1 2e-06 27.5 2.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORY36106.1 - 0.00087 18.7 0.5 0.0019 17.6 0.0 1.7 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 ORY36106.1 - 0.0016 18.0 1.2 1.9 8.0 0.1 2.7 2 0 0 2 2 2 2 Ferrous iron transport protein B cobW PF02492.19 ORY36106.1 - 0.05 13.2 2.7 0.72 9.4 0.1 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DUF2067 PF09840.9 ORY36106.1 - 0.054 13.1 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) Arf PF00025.21 ORY36106.1 - 0.077 12.4 2.2 5.3 6.4 0.0 3.1 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_29 PF13555.6 ORY36106.1 - 0.092 12.5 0.2 0.3 10.8 0.2 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain FolB PF02152.18 ORY36106.1 - 0.19 12.3 2.2 0.23 12.0 0.4 2.2 2 0 0 2 2 2 0 Dihydroneopterin aldolase AbiH PF14253.6 ORY36106.1 - 0.21 11.4 0.4 0.86 9.4 0.4 1.9 1 1 0 1 1 1 0 Bacteriophage abortive infection AbiH CbeA_antitoxin PF06154.11 ORY36107.1 - 0.015 15.9 0.1 0.019 15.6 0.1 1.2 1 0 0 1 1 1 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A Apolipoprotein PF01442.18 ORY36108.1 - 7.7e-06 25.9 11.0 1.2e-05 25.3 11.0 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain KfrA_N PF11740.8 ORY36108.1 - 6e-05 23.7 13.0 9.6e-05 23.0 13.0 1.4 1 0 0 1 1 1 1 Plasmid replication region DNA-binding N-term WEMBL PF05701.11 ORY36108.1 - 6.9e-05 21.7 16.4 9.1e-05 21.3 16.4 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light AAA_13 PF13166.6 ORY36108.1 - 7.8e-05 21.5 8.1 9.4e-05 21.3 8.1 1.0 1 0 0 1 1 1 1 AAA domain AIP3 PF03915.13 ORY36108.1 - 0.00033 19.9 1.5 0.00039 19.6 1.5 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 Baculo_PEP_C PF04513.12 ORY36108.1 - 0.00053 20.0 0.4 0.0085 16.1 0.0 2.1 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.21 ORY36108.1 - 0.0015 18.1 9.6 0.0021 17.7 9.6 1.1 1 0 0 1 1 1 1 Intermediate filament protein Spc7 PF08317.11 ORY36108.1 - 0.0033 16.4 10.2 0.0047 15.9 10.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4407 PF14362.6 ORY36108.1 - 0.0037 16.7 8.0 0.0053 16.1 8.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) CLZ PF16526.5 ORY36108.1 - 0.0048 17.2 7.6 0.025 15.0 3.9 2.6 1 1 1 2 2 2 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Golgin_A5 PF09787.9 ORY36108.1 - 0.0089 15.5 7.7 0.012 15.1 7.7 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF3584 PF12128.8 ORY36108.1 - 0.01 13.4 9.4 0.013 13.0 9.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Phage_GPO PF05929.11 ORY36108.1 - 0.011 15.4 6.7 0.017 14.7 6.7 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DLP_helical PF18709.1 ORY36108.1 - 0.013 14.7 9.0 0.44 9.7 4.9 2.1 1 1 1 2 2 2 0 Dynamin-like helical domain YlqD PF11068.8 ORY36108.1 - 0.015 15.7 7.8 0.023 15.1 7.8 1.3 1 0 0 1 1 1 0 YlqD protein Rootletin PF15035.6 ORY36108.1 - 0.015 15.3 8.2 0.022 14.8 8.2 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion ISG65-75 PF11727.8 ORY36108.1 - 0.017 14.4 12.4 0.027 13.7 12.4 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF1664 PF07889.12 ORY36108.1 - 0.017 15.1 4.9 0.038 14.0 4.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) UBN_AB PF14075.6 ORY36108.1 - 0.019 14.7 2.9 0.026 14.3 2.9 1.3 1 0 0 1 1 1 0 Ubinuclein conserved middle domain DUF2968 PF11180.8 ORY36108.1 - 0.023 14.3 7.2 0.034 13.8 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Alanine_zipper PF11839.8 ORY36108.1 - 0.027 14.8 18.8 0.027 14.8 18.8 2.2 2 1 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein ERM PF00769.19 ORY36108.1 - 0.03 14.1 13.7 0.046 13.5 13.7 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Mod_r PF07200.13 ORY36108.1 - 0.035 14.2 8.7 0.13 12.4 8.8 1.8 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein GHL15 PF14885.6 ORY36108.1 - 0.065 13.2 2.1 0.095 12.6 2.1 1.2 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 IFT57 PF10498.9 ORY36108.1 - 0.075 12.0 6.9 0.11 11.5 6.9 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 SpecificRecomb PF10136.9 ORY36108.1 - 0.081 11.2 2.8 0.1 10.9 2.8 1.0 1 0 0 1 1 1 0 Site-specific recombinase Exonuc_VII_L PF02601.15 ORY36108.1 - 0.092 12.3 4.1 0.12 11.9 4.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF724 PF05266.14 ORY36108.1 - 0.11 12.4 8.9 0.16 11.8 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Prominin PF05478.11 ORY36108.1 - 0.11 10.4 1.2 0.14 10.1 1.2 1.2 1 0 0 1 1 1 0 Prominin Borrelia_P83 PF05262.11 ORY36108.1 - 0.12 10.9 12.3 0.15 10.5 12.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Allexi_40kDa PF05549.11 ORY36108.1 - 0.13 11.7 1.1 0.49 9.9 1.0 1.9 2 0 0 2 2 2 0 Allexivirus 40kDa protein HisKA_3 PF07730.13 ORY36108.1 - 0.18 12.3 8.7 23 5.6 8.3 3.1 1 1 0 1 1 1 0 Histidine kinase Fib_alpha PF08702.10 ORY36108.1 - 0.19 11.9 3.8 0.37 11.0 3.0 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family AAA_23 PF13476.6 ORY36108.1 - 0.19 12.2 3.8 0.27 11.7 3.8 1.3 1 0 0 1 1 1 0 AAA domain Med9 PF07544.13 ORY36108.1 - 0.19 11.8 5.4 0.14 12.3 0.8 2.7 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF45 PF01863.17 ORY36108.1 - 0.21 11.6 4.1 0.3 11.1 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF45 Laminin_II PF06009.12 ORY36108.1 - 0.27 11.2 10.3 2 8.4 10.5 2.0 1 1 0 1 1 1 0 Laminin Domain II Seryl_tRNA_N PF02403.22 ORY36108.1 - 0.27 11.5 16.1 0.54 10.5 12.4 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.9 ORY36108.1 - 0.32 10.0 5.8 0.43 9.6 5.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 EzrA PF06160.12 ORY36108.1 - 0.35 9.0 13.0 2 6.5 13.2 1.6 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA NAM-associated PF14303.6 ORY36108.1 - 0.38 11.4 10.8 0.64 10.7 10.8 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Sipho_Gp157 PF05565.11 ORY36108.1 - 0.48 10.4 11.3 0.66 10.0 11.3 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 DUF4618 PF15397.6 ORY36108.1 - 0.51 9.7 9.6 2.2 7.6 9.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) DUF4200 PF13863.6 ORY36108.1 - 0.51 10.8 12.8 0.9 10.0 12.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Macoilin PF09726.9 ORY36108.1 - 0.52 8.8 7.3 0.64 8.5 7.3 1.1 1 0 0 1 1 1 0 Macoilin family Fez1 PF06818.15 ORY36108.1 - 0.57 10.6 12.5 0.89 10.0 12.5 1.3 1 1 0 1 1 1 0 Fez1 YkyA PF10368.9 ORY36108.1 - 0.67 9.6 14.7 2.3 7.9 14.9 1.6 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein PCRF PF03462.18 ORY36108.1 - 0.82 9.5 11.7 1.8 8.4 11.6 1.6 1 1 0 1 1 1 0 PCRF domain CCDC53 PF10152.9 ORY36108.1 - 0.84 10.0 6.4 1.3 9.4 6.4 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex FlaC_arch PF05377.11 ORY36108.1 - 0.86 10.0 7.4 0.91 10.0 0.8 2.8 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Cob_adeno_trans PF01923.18 ORY36108.1 - 1.1 9.4 5.0 2.2 8.4 5.0 1.4 1 1 0 1 1 1 0 Cobalamin adenosyltransferase KELK PF15796.5 ORY36108.1 - 1.4 9.4 12.7 2 8.9 11.9 1.7 1 1 0 1 1 1 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase T3SSipB PF16535.5 ORY36108.1 - 1.5 9.2 12.3 0.8 10.2 9.4 1.7 1 1 0 1 1 1 0 Type III cell invasion protein SipB TMPIT PF07851.13 ORY36108.1 - 1.7 7.8 5.8 2.5 7.3 5.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein Vfa1 PF08432.10 ORY36108.1 - 1.8 8.8 9.1 2.8 8.2 9.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Cnn_1N PF07989.11 ORY36108.1 - 1.9 8.7 11.5 44 4.3 11.5 2.4 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 APG6_N PF17675.1 ORY36108.1 - 2 9.0 20.0 4.3 7.9 20.0 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF3450 PF11932.8 ORY36108.1 - 2.4 7.4 13.6 1.6 8.0 11.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FUSC PF04632.12 ORY36108.1 - 2.6 6.5 3.5 3.5 6.1 3.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF948 PF06103.11 ORY36108.1 - 2.6 8.3 9.9 1.5 9.1 1.4 2.6 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) AIF-MLS PF14962.6 ORY36108.1 - 2.7 7.9 13.2 4.1 7.3 13.2 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence ZapB PF06005.12 ORY36108.1 - 2.9 8.4 17.2 12 6.4 17.2 2.0 1 1 0 1 1 1 0 Cell division protein ZapB COG2 PF06148.11 ORY36108.1 - 3.1 7.9 10.1 7.6 6.6 6.8 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DivIVA PF05103.13 ORY36108.1 - 3.4 7.7 14.9 8.2 6.5 14.9 1.7 1 1 0 1 1 1 0 DivIVA protein ADIP PF11559.8 ORY36108.1 - 3.8 7.6 13.7 7.9 6.5 13.3 1.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Prefoldin_2 PF01920.20 ORY36108.1 - 4.7 7.2 12.9 1.5 8.8 1.0 2.3 1 1 1 2 2 2 0 Prefoldin subunit DUF1690 PF07956.11 ORY36108.1 - 6.5 7.2 13.1 11 6.4 12.5 1.6 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) GST_C_2 PF13410.6 ORY36109.1 - 0.00039 20.4 0.0 0.0012 18.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY36109.1 - 0.0069 16.6 0.0 0.017 15.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY36109.1 - 0.0088 16.2 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Sel1 PF08238.12 ORY36110.1 - 9.4e-05 23.0 0.3 0.052 14.3 0.0 2.3 2 0 0 2 2 2 2 Sel1 repeat NAD_Gly3P_dh_C PF07479.14 ORY36111.1 - 7.2e-49 165.7 0.5 1.2e-48 165.1 0.5 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 ORY36111.1 - 1e-38 132.8 0.1 1.5e-38 132.2 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 ORY36111.1 - 3.3e-09 36.6 0.3 5.5e-09 35.8 0.3 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 ORY36111.1 - 2.7e-06 27.9 0.1 9.6e-06 26.1 0.0 2.0 2 0 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox PF00070.27 ORY36111.1 - 2.9e-05 24.5 0.7 0.0021 18.6 0.1 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY36111.1 - 0.00077 18.8 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ORY36111.1 - 0.00088 19.4 0.0 0.0035 17.4 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 ORY36111.1 - 0.0014 19.0 0.0 0.0026 18.2 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_2 PF03446.15 ORY36111.1 - 0.0014 18.8 0.1 0.0048 17.1 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.14 ORY36111.1 - 0.0028 17.2 0.2 0.0049 16.5 0.2 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 ORY36111.1 - 0.0031 17.7 0.2 0.008 16.4 0.1 1.7 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox_2 PF07992.14 ORY36111.1 - 0.0036 16.6 0.3 0.0081 15.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 ORY36111.1 - 0.0077 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 ORY36111.1 - 0.032 14.1 0.2 0.063 13.2 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 ORY36111.1 - 0.032 14.5 0.4 0.27 11.5 0.1 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain IlvN PF07991.12 ORY36111.1 - 0.034 13.7 0.4 0.66 9.5 0.4 2.4 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 ORY36111.1 - 0.042 13.1 0.1 0.074 12.3 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DpaA_N PF16924.5 ORY36111.1 - 0.11 12.6 0.2 0.48 10.5 0.2 2.0 1 1 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain DAO PF01266.24 ORY36111.1 - 0.2 11.2 0.2 0.2 11.2 0.2 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase SAM_2 PF07647.17 ORY36112.1 - 2.1e-05 24.6 0.0 4.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORY36112.1 - 4.6e-05 23.8 0.0 8.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 ORY36112.1 - 0.0012 18.7 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Gram_pos_anchor PF00746.21 ORY36112.1 - 0.013 15.4 2.4 0.014 15.3 0.6 1.9 2 0 0 2 2 2 0 LPXTG cell wall anchor motif gp12-short_mid PF09089.10 ORY36112.1 - 0.15 12.2 0.1 0.56 10.4 0.0 1.9 2 0 0 2 2 2 0 Phage short tail fibre protein gp12, middle domain Ciart PF15673.5 ORY36112.1 - 0.7 9.2 8.0 1.9 7.8 8.0 1.7 1 0 0 1 1 1 0 Circadian-associated transcriptional repressor NADH_u_ox_C PF12853.7 ORY36112.1 - 1.4 9.0 11.0 1.6 8.7 1.6 3.3 1 1 1 2 2 2 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit CAMSAP_CKK PF08683.11 ORY36113.1 - 4.7e-15 55.8 0.0 1.2e-14 54.5 0.0 1.7 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated CH_2 PF06294.11 ORY36113.1 - 0.0081 16.3 0.0 0.02 15.0 0.0 1.7 1 0 0 1 1 1 1 CH-like domain in sperm protein START PF01852.19 ORY36115.1 - 0.14 11.6 0.1 2.2 7.6 0.1 2.0 1 1 0 1 1 1 0 START domain Ion_trans_2 PF07885.16 ORY36116.1 - 8.4e-05 22.5 6.0 8.4e-05 22.5 6.0 1.8 2 0 0 2 2 2 1 Ion channel KAR9 PF08580.10 ORY36116.1 - 2.2 6.7 6.3 3.3 6.1 6.3 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Ion_trans_2 PF07885.16 ORY36117.1 - 2.6e-15 56.1 8.1 3.8e-15 55.6 8.1 1.2 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 ORY36117.1 - 0.01 15.1 4.3 0.018 14.3 4.3 1.3 1 1 0 1 1 1 0 Ion transport protein YwpF PF14183.6 ORY36118.1 - 0.01 15.8 0.0 0.42 10.6 0.0 3.1 2 0 0 2 2 2 0 YwpF-like protein LOR PF04525.12 ORY36119.1 - 0.00026 20.6 0.2 0.00071 19.2 0.0 1.7 2 0 0 2 2 2 1 LURP-one-related Pentapeptide PF00805.22 ORY36120.1 - 0.0002 20.9 0.3 0.0014 18.2 0.3 2.0 1 1 0 1 1 1 1 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 ORY36120.1 - 0.01 16.0 0.6 0.012 15.7 0.6 1.2 1 0 0 1 1 1 0 Pentapeptide repeats (9 copies) VASt PF16016.5 ORY36121.1 - 6.5e-05 23.4 0.0 0.00013 22.4 0.0 1.5 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain TFIIA PF03153.13 ORY36121.1 - 0.13 12.3 15.8 0.19 11.7 15.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TPR_17 PF13431.6 ORY36122.1 - 0.022 15.1 0.1 0.21 12.1 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY36122.1 - 0.1 12.9 0.2 34 4.8 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat NAPRTase_N PF17767.1 ORY36122.1 - 0.15 12.4 1.7 7.8 6.9 0.0 3.7 3 1 1 4 4 4 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain TPR_8 PF13181.6 ORY36122.1 - 0.22 11.8 1.1 0.99 9.8 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY36122.1 - 2.3 8.6 5.6 1.3 9.4 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat LtrA PF06772.11 ORY36123.1 - 1.3e-106 356.8 66.9 1.8e-53 182.0 28.4 2.2 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) HU-DNA_bdg PF14848.6 ORY36123.1 - 0.014 15.4 0.1 0.45 10.5 0.0 2.3 2 0 0 2 2 2 0 DNA-binding domain IBP39 PF11422.8 ORY36123.1 - 0.017 14.9 0.1 2 8.1 0.0 2.3 2 0 0 2 2 2 0 Initiator binding protein 39 kDa VirB7 PF17413.2 ORY36123.1 - 0.054 12.8 0.1 3.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Outer membrane lipoprotein virB7 Bee_toxin PF17454.2 ORY36123.1 - 5.7 7.1 6.5 17 5.5 0.8 3.6 2 0 0 2 2 2 0 Honey bee toxin Amidohydro_3 PF07969.11 ORY36124.1 - 2e-55 189.1 0.0 2.4e-55 188.9 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family TMEM154 PF15102.6 ORY36126.1 - 2.2e-08 34.1 2.7 2.2e-08 34.1 2.7 3.1 2 1 0 2 2 1 1 TMEM154 protein family SH3_9 PF14604.6 ORY36126.1 - 4.9e-06 26.3 0.1 8.2e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF3377 PF11857.8 ORY36126.1 - 0.0046 16.9 0.1 0.0091 15.9 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) DUF4448 PF14610.6 ORY36126.1 - 0.0057 16.5 0.7 0.011 15.5 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) m04gp34like PF12216.8 ORY36126.1 - 0.01 15.4 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 0 Immune evasion protein DUF2244 PF10003.9 ORY36126.1 - 0.02 14.6 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Stevor PF17410.2 ORY36126.1 - 0.028 14.0 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame PgaD PF13994.6 ORY36126.1 - 0.045 13.8 0.3 0.088 12.9 0.3 1.4 1 0 0 1 1 1 0 PgaD-like protein SKG6 PF08693.10 ORY36126.1 - 0.045 13.2 0.6 0.14 11.5 0.6 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2723 PF11028.8 ORY36126.1 - 0.054 13.4 0.1 0.085 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2723) EphA2_TM PF14575.6 ORY36126.1 - 0.056 14.3 4.4 0.13 13.2 0.1 2.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain MLANA PF14991.6 ORY36126.1 - 0.092 13.0 0.0 0.092 13.0 0.0 2.6 3 0 0 3 3 2 0 Protein melan-A MAP17 PF15807.5 ORY36126.1 - 0.099 12.9 0.3 0.099 12.9 0.3 2.2 2 1 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Syndecan PF01034.20 ORY36126.1 - 0.1 12.5 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain DUF4006 PF13179.6 ORY36126.1 - 0.13 12.2 0.6 0.38 10.7 0.6 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF4006) Peptidase_M56 PF05569.11 ORY36126.1 - 0.16 11.1 1.5 0.32 10.1 1.5 1.5 1 0 0 1 1 1 0 BlaR1 peptidase M56 SH3_1 PF00018.28 ORY36126.1 - 0.18 11.4 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 SH3 domain RIFIN PF02009.16 ORY36126.1 - 0.23 11.3 2.3 0.68 9.8 0.0 2.1 2 0 0 2 2 2 0 Rifin DUF5385 PF17359.2 ORY36126.1 - 0.34 10.4 2.0 0.73 9.4 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5385) SARAF PF06682.12 ORY36126.1 - 0.52 9.9 15.5 0.64 9.6 0.5 2.5 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis SIT PF15330.6 ORY36126.1 - 6 7.3 10.8 0.37 11.2 0.3 3.1 3 0 0 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT MscS_TM PF12794.7 ORY36126.1 - 9.3 5.0 6.7 2.3 7.0 0.1 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 PMSR PF01625.21 ORY36127.1 - 3.4e-59 199.4 0.4 4.2e-59 199.1 0.4 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase PMSR PF01625.21 ORY36128.1 - 1.6e-58 197.2 0.8 2e-58 196.9 0.8 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Mito_carr PF00153.27 ORY36129.1 - 7.4e-65 214.9 6.0 7.3e-23 80.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CsgE PF10627.9 ORY36130.1 - 0.12 12.7 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Curli assembly protein CsgE TMEM135_C_rich PF15982.5 ORY36133.1 - 3.9e-07 30.7 5.6 6.1e-06 26.9 0.4 2.9 3 0 0 3 3 3 2 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 ORY36133.1 - 0.015 15.7 3.9 0.55 10.6 3.2 2.8 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Homeodomain PF00046.29 ORY36134.1 - 0.0085 15.9 0.1 0.02 14.7 0.1 1.6 1 0 0 1 1 1 1 Homeodomain PMSI1 PF15322.6 ORY36134.1 - 0.29 10.5 7.0 0.036 13.5 1.3 1.9 2 0 0 2 2 2 0 Protein missing in infertile sperm 1, putative DEAD PF00270.29 ORY36135.1 - 7.1e-28 97.5 0.6 1.1e-27 96.9 0.6 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY36135.1 - 5.5e-18 65.3 0.0 4.7e-17 62.3 0.0 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY36135.1 - 0.00068 19.7 0.0 0.0039 17.2 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 ORY36135.1 - 0.0093 15.3 0.2 0.037 13.4 0.2 1.9 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit DUF3824 PF12868.7 ORY36135.1 - 0.047 14.4 3.2 0.14 12.8 3.2 1.8 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Ribosomal_60s PF00428.19 ORY36135.1 - 8.6 7.0 8.6 3.3 8.4 5.0 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Spt20 PF12090.8 ORY36136.1 - 0.44 10.1 48.4 1.6 8.3 22.3 2.2 2 0 0 2 2 2 0 Spt20 family Med15 PF09606.10 ORY36136.1 - 1.1 7.9 56.2 2.7 6.5 56.2 1.5 1 1 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HLH PF00010.26 ORY36137.1 - 4.9e-15 55.2 0.8 7.1e-15 54.7 0.8 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CRAL_TRIO PF00650.20 ORY36138.1 - 1.2e-21 77.1 0.0 1.6e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 ORY36138.1 - 0.0017 18.5 0.0 0.0028 17.8 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain UQ_con PF00179.26 ORY36139.1 - 3.7e-21 75.2 0.1 6.1e-21 74.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY36139.1 - 0.046 14.0 0.1 0.046 14.0 0.1 2.0 2 0 0 2 2 2 0 RWD domain RRP36 PF06102.12 ORY36139.1 - 0.13 12.2 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 Aldedh PF00171.22 ORY36140.1 - 7.8e-135 450.0 0.9 9.5e-135 449.7 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRM_1 PF00076.22 ORY36141.1 - 0.00068 19.4 0.1 0.0067 16.2 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 ORY36142.1 - 9.3e-06 26.4 0.1 1.8e-05 25.5 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CCDC117 PF15810.5 ORY36142.1 - 0.032 14.5 0.1 0.065 13.5 0.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 117 WRNPLPNID PF15017.6 ORY36142.1 - 0.08 13.8 0.1 0.13 13.1 0.1 1.4 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box Putative_PNPOx PF01243.20 ORY36143.1 - 8.6e-23 80.3 0.0 1.3e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 ORY36143.1 - 2.3e-17 62.8 1.2 5.9e-17 61.5 1.2 1.7 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region APG6_N PF17675.1 ORY36144.1 - 3.9e-05 24.2 17.4 3.9e-05 24.2 17.4 7.2 2 1 5 7 7 7 1 Apg6 coiled-coil region KilA-N PF04383.13 ORY36145.1 - 1.1e-06 28.5 0.0 1.3e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 KilA-N domain LAT PF15234.6 ORY36145.1 - 0.005 16.6 0.7 0.0073 16.1 0.7 1.2 1 0 0 1 1 1 1 Linker for activation of T-cells Beach PF02138.18 ORY36146.1 - 3.8e-129 429.9 0.5 2.1e-128 427.5 0.2 2.1 2 0 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 ORY36146.1 - 1.2e-26 93.6 2.2 2.3e-26 92.7 0.3 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 ORY36146.1 - 5.9e-22 77.6 0.2 1.2e-21 76.6 0.2 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 ORY36146.1 - 1.2e-14 54.2 2.2 3e-14 52.9 2.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) WD40 PF00400.32 ORY36146.1 - 1.4e-11 44.7 6.0 0.00011 22.8 0.2 4.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Laminin_G_3 PF13385.6 ORY36146.1 - 9.6e-05 22.6 0.1 0.00054 20.1 0.1 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF1088 PF06469.11 ORY36146.1 - 0.0011 18.7 1.4 0.0023 17.6 1.4 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) DUF3040 PF11239.8 ORY36147.1 - 0.0048 17.1 1.9 0.016 15.4 1.9 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) AA_permease PF00324.21 ORY36149.1 - 9.3e-115 383.9 41.8 1.1e-114 383.6 41.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY36149.1 - 1.3e-35 123.1 45.5 1.6e-35 122.8 45.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1449 PF07290.11 ORY36149.1 - 0.041 13.5 1.3 0.13 11.8 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) Vpu PF00558.19 ORY36149.1 - 2.4 8.0 3.5 5.6 6.8 3.5 1.5 1 0 0 1 1 1 0 Vpu protein zf-CCCH PF00642.24 ORY36151.1 - 3 7.9 16.9 0.33 10.9 3.9 3.4 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) UNC-50 PF05216.13 ORY36152.1 - 1.7e-90 302.5 25.8 1.9e-90 302.3 25.8 1.0 1 0 0 1 1 1 1 UNC-50 family Slu7 PF11708.8 ORY36153.1 - 2.9e-102 342.0 9.8 2.9e-102 342.0 9.8 2.3 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 ORY36153.1 - 0.16 11.7 2.2 0.33 10.7 0.5 2.1 2 0 0 2 2 2 0 Zinc knuckle Ribosomal_S17_N PF16205.5 ORY36154.1 - 8e-30 103.0 0.4 1.7e-29 102.0 0.4 1.6 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 ORY36154.1 - 6.6e-28 96.6 0.3 9.4e-28 96.1 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Mob_synth_C PF06463.13 ORY36155.1 - 2.6e-36 124.4 0.0 4.1e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 ORY36155.1 - 2.5e-29 102.8 0.0 1.1e-28 100.7 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 ORY36155.1 - 1.2e-05 25.6 0.0 2.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 ORY36155.1 - 7.2e-05 22.9 0.0 0.00018 21.6 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain PhoLip_ATPase_C PF16212.5 ORY36156.1 - 6.6e-64 216.0 26.1 6.6e-64 216.0 26.1 2.7 2 1 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY36156.1 - 7.8e-24 83.1 1.8 7.8e-24 83.1 1.8 2.4 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 ORY36156.1 - 1.6e-12 47.3 0.0 9.7e-12 44.8 0.0 2.3 2 1 1 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY36156.1 - 3.6e-09 37.2 0.1 0.015 15.6 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORY36156.1 - 2.4e-06 27.2 0.0 2.4e-06 27.2 0.0 3.2 3 1 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 ORY36156.1 - 0.00072 19.4 0.1 0.0037 17.1 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LRR_9 PF14580.6 ORY36157.1 - 3.5e-11 42.9 1.2 2.3e-08 33.7 0.1 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_4 PF12799.7 ORY36157.1 - 5.9e-08 32.9 13.5 0.0019 18.6 0.4 3.6 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY36157.1 - 8.2e-07 28.7 11.5 0.002 17.8 3.7 3.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 ORY36157.1 - 0.17 12.0 6.2 7.2 6.9 0.0 3.7 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 ORY36157.1 - 2.7 8.9 13.3 9.7 7.2 0.5 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat Cyclin_N PF00134.23 ORY36158.1 - 7.7e-47 158.2 0.5 5.8e-45 152.1 0.3 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORY36158.1 - 3.6e-35 120.6 0.4 6.4e-35 119.8 0.4 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Arginosuc_synth PF00764.19 ORY36160.1 - 9.5e-159 528.8 0.0 1.1e-158 528.6 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 ORY36160.1 - 0.003 17.1 0.0 0.0047 16.4 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 ORY36160.1 - 0.0058 15.5 0.0 0.0093 14.8 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase MFS_1 PF07690.16 ORY36161.1 - 2.3e-28 99.1 35.0 3.1e-28 98.7 35.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 ORY36161.1 - 9.7e-09 34.3 9.1 9.7e-09 34.3 9.1 2.1 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.16 ORY36162.1 - 2e-29 102.6 33.2 3e-29 102.1 33.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 ORY36162.1 - 1.3e-06 27.3 13.4 1.3e-06 27.3 13.4 2.2 1 1 1 2 2 2 1 MFS/sugar transport protein Ndc1_Nup PF09531.10 ORY36164.1 - 0.0098 14.6 0.7 0.013 14.2 0.7 1.2 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup EOS1 PF12326.8 ORY36164.1 - 0.044 13.7 0.2 0.056 13.4 0.2 1.4 1 1 0 1 1 1 0 N-glycosylation protein ATG7_N PF16420.5 ORY36165.1 - 5.6e-87 292.2 0.0 8.4e-87 291.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 ORY36165.1 - 7.4e-44 149.9 0.0 1.1e-43 149.4 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 ORY36165.1 - 0.006 16.7 0.0 0.021 14.9 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 ORY36165.1 - 0.16 11.6 0.1 0.71 9.5 0.0 2.2 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA CRAL_TRIO PF00650.20 ORY36166.1 - 2.7e-14 53.2 0.0 4.4e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain MRI PF15325.6 ORY36166.1 - 4.3 8.5 6.1 7.6 7.7 0.4 2.7 2 1 1 3 3 3 0 Modulator of retrovirus infection Ank_2 PF12796.7 ORY36167.1 - 5.8e-19 68.5 0.6 1.3e-13 51.3 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY36167.1 - 6.4e-19 68.1 0.9 1.1e-05 25.9 0.1 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY36167.1 - 1.7e-17 63.2 2.0 1.8e-06 28.1 0.1 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY36167.1 - 6.3e-15 54.9 5.4 0.0068 16.8 0.0 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 ORY36167.1 - 1.9e-14 52.3 2.3 0.0091 16.4 0.1 4.6 5 0 0 5 5 5 4 Ankyrin repeat Nmad3 PF18754.1 ORY36167.1 - 0.053 13.1 0.0 0.062 12.9 0.0 1.1 1 0 0 1 1 1 0 Nucleotide modification associated domain 3 TIR_2 PF13676.6 ORY36168.1 - 2.8e-14 53.7 0.0 6.5e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 TIR domain NACHT PF05729.12 ORY36168.1 - 0.07 13.0 0.0 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.13 ORY36168.1 - 0.13 11.6 0.2 6.2 6.1 0.0 2.2 2 0 0 2 2 2 0 KaiC Rcd1 PF04078.13 ORY36170.1 - 1.4e-125 417.8 2.4 1.6e-125 417.6 2.4 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Pigment_DH PF06324.11 ORY36170.1 - 0.15 12.2 0.3 0.37 11.0 0.3 1.7 1 0 0 1 1 1 0 Pigment-dispersing hormone (PDH) MRP-L20 PF12824.7 ORY36172.1 - 5.9e-11 42.8 1.2 6.7e-11 42.6 1.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 ThiF PF00899.21 ORY36173.1 - 8.3e-27 94.1 0.0 2.1e-26 92.8 0.0 1.6 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 ORY36173.1 - 0.00039 20.6 0.1 0.16 12.2 0.0 3.5 3 1 0 3 3 3 1 Ubiquitin-activating enzyme E1 four-helix bundle DUF5010 PF16402.5 ORY36173.1 - 0.13 11.0 0.0 0.29 9.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5010) PMM PF03332.13 ORY36174.1 - 5.1e-90 301.1 0.2 6.5e-90 300.7 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 ORY36174.1 - 6.5e-06 26.1 0.0 3.7e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 ORY36174.1 - 0.00039 20.0 0.0 0.13 11.7 0.0 2.0 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Glyco_hydro_75 PF07335.11 ORY36174.1 - 0.0096 16.2 0.0 0.015 15.6 0.0 1.5 1 1 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Hydrolase PF00702.26 ORY36174.1 - 0.035 14.4 0.1 0.046 14.0 0.1 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY36174.1 - 0.14 12.2 0.0 0.22 11.6 0.0 1.4 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ANAPC4_WD40 PF12894.7 ORY36175.1 - 0.00027 21.2 0.0 4.2 7.7 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 ORY36175.1 - 0.0062 15.5 0.1 0.011 14.7 0.1 1.4 1 0 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain dCMP_cyt_deam_1 PF00383.23 ORY36177.1 - 2.4e-23 81.9 0.1 3.3e-23 81.5 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY36177.1 - 3.2e-21 75.5 0.5 5.7e-20 71.5 0.5 2.0 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 ORY36177.1 - 0.04 14.0 0.7 0.083 13.0 0.7 1.5 1 1 0 1 1 1 0 Bd3614-like deaminase MTS PF05175.14 ORY36178.1 - 2.2e-08 33.9 0.0 2.4e-06 27.2 0.0 2.0 2 0 0 2 2 2 2 Methyltransferase small domain DUF938 PF06080.12 ORY36178.1 - 0.021 14.6 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_12 PF08242.12 ORY36178.1 - 0.034 14.9 0.0 0.06 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 ORY36178.1 - 0.1 13.3 0.0 0.18 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AAA_12 PF13087.6 ORY36180.1 - 8.9e-30 103.8 0.0 1e-29 103.6 0.0 1.0 1 0 0 1 1 1 1 AAA domain Mcm10 PF09332.11 ORY36181.1 - 0.31 10.4 4.4 0.63 9.4 4.4 1.5 1 0 0 1 1 1 0 Mcm10 replication factor dsrm PF00035.26 ORY36182.1 - 1.1e-18 67.7 0.0 3.3e-10 40.5 0.0 3.5 3 0 0 3 3 3 3 Double-stranded RNA binding motif OAS1_C PF10421.9 ORY36182.1 - 1.4e-06 27.9 0.5 2.5e-06 27.1 0.5 1.3 1 0 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus DND1_DSRM PF14709.7 ORY36182.1 - 2.5e-05 24.5 1.0 0.05 13.9 0.0 3.7 3 0 0 3 3 3 2 double strand RNA binding domain from DEAD END PROTEIN 1 Dicer_dimer PF03368.14 ORY36182.1 - 0.027 14.6 0.5 0.92 9.7 0.1 3.2 3 0 0 3 3 3 0 Dicer dimerisation domain DUF667 PF05018.13 ORY36183.1 - 1.7e-93 311.5 1.8 1.9e-93 311.3 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) ELFV_dehydrog PF00208.21 ORY36184.1 - 1.3e-57 195.3 0.0 2e-57 194.7 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 ORY36184.1 - 2.8e-23 81.5 0.0 2.1e-16 58.7 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 ORY36184.1 - 0.16 11.9 0.0 0.68 9.8 0.0 2.0 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Nod1 PF17114.5 ORY36184.1 - 1.5 9.0 5.4 2.7 8.2 0.2 3.0 3 0 0 3 3 3 0 Gef2-related medial cortical node protein Nod1 ABC_membrane PF00664.23 ORY36185.1 - 2.3e-49 168.5 32.5 3.2e-28 99.2 11.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY36185.1 - 1.2e-48 165.1 0.0 1.3e-26 93.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY36185.1 - 2.2e-09 37.1 5.5 0.014 14.8 0.1 4.2 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY36185.1 - 1.6e-06 27.7 2.2 0.04 13.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 ORY36185.1 - 2.7e-06 26.6 0.0 0.014 14.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 ORY36185.1 - 4.9e-06 27.0 0.2 0.064 13.6 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORY36185.1 - 5e-06 26.5 0.6 0.0037 17.2 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ORY36185.1 - 6.6e-06 26.2 1.1 0.12 12.5 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 ORY36185.1 - 2e-05 25.2 0.7 0.17 12.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 ORY36185.1 - 2.5e-05 24.2 0.9 0.095 12.5 0.0 4.0 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 ORY36185.1 - 0.00032 20.0 1.0 0.29 10.4 0.1 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.6 ORY36185.1 - 0.0004 20.2 3.2 1 9.1 0.1 3.7 4 0 0 4 4 4 2 AAA domain AAA_7 PF12775.7 ORY36185.1 - 0.00041 19.9 0.2 0.8 9.2 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region NB-ARC PF00931.22 ORY36185.1 - 0.0032 16.7 0.2 1.9 7.6 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_15 PF13175.6 ORY36185.1 - 0.0071 16.1 0.3 0.039 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 ORY36185.1 - 0.025 13.8 0.1 3.7 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Dynamin_N PF00350.23 ORY36185.1 - 0.039 14.0 3.4 0.89 9.6 0.9 2.5 2 0 0 2 2 2 0 Dynamin family AAA_22 PF13401.6 ORY36185.1 - 0.049 13.9 1.1 6.3 7.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 ORY36185.1 - 0.11 12.0 1.0 2 7.9 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 ORY36185.1 - 0.14 12.4 0.7 23 5.2 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 ORY36185.1 - 0.23 10.7 1.7 3.3 7.0 0.1 2.6 2 0 0 2 2 2 0 AIG1 family ATP_bind_1 PF03029.17 ORY36185.1 - 0.36 10.6 2.0 7.2 6.3 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 ORY36185.1 - 0.59 9.4 2.3 20 4.5 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family CBS PF00571.28 ORY36186.1 - 4.5e-23 81.5 3.6 7e-06 26.4 0.0 4.7 4 0 0 4 4 4 4 CBS domain BTB_2 PF02214.22 ORY36186.1 - 2.7e-08 34.1 0.0 5.5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain PB1 PF00564.24 ORY36186.1 - 0.004 17.1 0.0 0.01 15.8 0.0 1.7 1 0 0 1 1 1 1 PB1 domain GAF PF01590.26 ORY36186.1 - 0.11 13.1 0.4 2.7 8.6 0.0 2.8 2 1 1 3 3 3 0 GAF domain BTB PF00651.31 ORY36186.1 - 0.14 12.4 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain RPN1_RPN2_N PF17781.1 ORY36187.1 - 7.2e-120 400.0 0.0 1.1e-119 399.4 0.0 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 ORY36187.1 - 1.1e-31 108.6 0.1 2.5e-31 107.5 0.1 1.7 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 ORY36187.1 - 8.2e-29 98.6 13.4 1e-05 25.7 0.2 8.6 8 0 0 8 8 8 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 ORY36187.1 - 1.5e-05 25.3 1.5 0.44 11.0 0.1 4.0 3 2 1 4 4 4 3 HEAT repeats Tfb2 PF03849.14 ORY36191.1 - 1.3e-128 429.0 0.1 1.7e-128 428.6 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 ORY36191.1 - 1.2e-22 80.0 0.0 3e-22 78.8 0.0 1.7 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 ORY36191.1 - 0.011 15.9 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain SinI PF08671.10 ORY36191.1 - 0.058 13.2 0.0 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 Anti-repressor SinI PLA2_B PF01735.18 ORY36192.1 - 2.3e-37 128.6 0.0 1.3e-20 73.3 0.0 2.1 2 0 0 2 2 2 2 Lysophospholipase catalytic domain TetR_C_15 PF17918.1 ORY36192.1 - 0.32 11.8 1.7 1.9 9.2 1.4 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain PAP1 PF08601.10 ORY36192.1 - 0.67 9.6 9.1 1.2 8.8 9.1 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 SUIM_assoc PF16619.5 ORY36194.1 - 2.3 8.3 7.0 0.77 9.9 1.6 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 GatB_N PF02934.15 ORY36195.1 - 5e-99 331.1 0.0 6.1e-99 330.8 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 ORY36195.1 - 1.4e-26 93.1 0.1 7.3e-26 90.8 0.1 2.0 1 1 0 1 1 1 1 GatB domain p450 PF00067.22 ORY36196.1 - 1.7e-52 178.7 0.0 2.1e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Gp138_N PF18352.1 ORY36198.1 - 0.031 14.3 0.1 0.36 10.9 0.0 2.5 3 0 0 3 3 3 0 Phage protein Gp138 N-terminal domain F-box-like PF12937.7 ORY36198.1 - 0.067 13.1 0.3 0.15 12.0 0.3 1.6 1 0 0 1 1 1 0 F-box-like Pkinase PF00069.25 ORY36199.1 - 2.3e-59 200.9 0.1 6.5e-53 179.8 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY36199.1 - 1.2e-34 119.8 0.0 2.4e-34 118.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY36199.1 - 0.00046 19.2 0.0 0.00084 18.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY36199.1 - 0.0061 16.5 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORY36199.1 - 0.016 14.8 0.1 0.025 14.2 0.1 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 ORY36199.1 - 0.028 13.8 0.1 0.046 13.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY36199.1 - 0.036 13.4 0.0 0.22 10.8 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Choline_kinase PF01633.20 ORY36199.1 - 0.12 12.0 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Herpes_DNAp_acc PF04929.12 ORY36199.1 - 2.8 6.8 5.6 1.1 8.1 2.3 1.8 2 0 0 2 2 2 0 Herpes DNA replication accessory factor SH3_1 PF00018.28 ORY36200.1 - 0.00023 20.7 0.0 0.00078 19.0 0.0 1.9 2 0 0 2 2 2 1 SH3 domain CTD_bind PF04818.13 ORY36201.1 - 1.5e-17 64.1 0.4 6.1e-17 62.2 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase II-binding domain. zf-C4H2 PF10146.9 ORY36201.1 - 5.2 7.3 15.1 0.63 10.3 8.2 2.4 1 1 1 2 2 2 0 Zinc finger-containing protein Glyco_hydro_18 PF00704.28 ORY36203.1 - 7.2e-10 39.1 0.0 6.7e-06 26.1 0.0 2.6 2 1 0 2 2 2 2 Glycosyl hydrolases family 18 tRNA-synt_2b PF00587.25 ORY36204.1 - 1.7e-18 67.3 0.0 1e-17 64.7 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 ORY36204.1 - 4.3e-09 36.6 2.2 4.3e-09 36.6 2.2 1.6 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DASH_Spc34 PF08657.10 ORY36204.1 - 0.032 14.0 1.7 0.06 13.1 1.7 1.4 1 0 0 1 1 1 0 DASH complex subunit Spc34 NDK PF00334.19 ORY36205.1 - 1.7e-52 177.0 0.0 1.9e-52 176.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.18 ORY36205.1 - 0.16 12.5 0.0 0.34 11.5 0.0 1.6 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ peroxidase PF00141.23 ORY36206.1 - 1.6e-47 162.1 0.0 2.3e-47 161.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase MFS_1 PF07690.16 ORY36207.1 - 2.8e-25 89.0 18.8 4.6e-25 88.3 18.8 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 ORY36207.1 - 0.00013 20.5 2.7 0.00022 19.8 2.7 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.16 ORY36208.1 - 9.8e-22 77.3 41.5 1.4e-21 76.8 41.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 ORY36208.1 - 8.5e-07 27.7 5.5 1.8e-06 26.7 5.5 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector NapE PF06796.11 ORY36208.1 - 1 9.0 6.2 0.1 12.2 0.7 2.3 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE Pho88 PF10032.9 ORY36209.1 - 1.2e-50 171.3 1.6 1.5e-50 171.0 1.6 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) NAD_binding_8 PF13450.6 ORY36210.1 - 8.5e-11 41.9 1.2 7.8e-09 35.6 0.5 2.6 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY36210.1 - 7.8e-06 25.3 0.1 1.9e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY36210.1 - 0.00015 21.5 1.7 0.00026 20.7 1.7 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 ORY36210.1 - 0.00017 21.0 0.2 0.42 9.8 0.5 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 ORY36210.1 - 0.00024 20.3 1.6 0.0004 19.6 1.6 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 ORY36210.1 - 0.00025 20.4 0.3 0.00053 19.3 0.3 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 ORY36210.1 - 0.00036 19.9 0.4 0.00057 19.2 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ORY36210.1 - 0.0011 19.5 0.5 0.0022 18.5 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 ORY36210.1 - 0.0071 16.0 2.7 1.2 8.8 0.5 2.4 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 ORY36210.1 - 0.0075 15.4 0.5 0.012 14.7 0.5 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein 3HCDH_N PF02737.18 ORY36210.1 - 0.012 15.5 0.7 0.021 14.7 0.7 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.19 ORY36210.1 - 0.019 13.4 0.0 0.03 12.7 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like HI0933_like PF03486.14 ORY36210.1 - 0.023 13.4 0.4 0.039 12.7 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 ORY36210.1 - 0.03 13.4 1.4 0.045 12.8 1.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 ORY36210.1 - 0.076 12.3 0.5 0.13 11.6 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 ORY36210.1 - 0.2 11.6 0.3 0.49 10.4 0.3 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding BUD22 PF09073.10 ORY36211.1 - 1.9 7.8 11.8 2.3 7.5 11.8 1.1 1 0 0 1 1 1 0 BUD22 ZapB PF06005.12 ORY36268.1 - 0.00048 20.5 2.7 0.00062 20.2 2.7 1.2 1 0 0 1 1 1 1 Cell division protein ZapB DUF3450 PF11932.8 ORY36268.1 - 0.0023 17.3 1.5 0.0029 17.0 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Nsp1_C PF05064.13 ORY36268.1 - 0.0024 17.7 1.7 0.003 17.3 1.7 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region BLOC1_2 PF10046.9 ORY36268.1 - 0.0044 17.3 0.7 0.0058 16.9 0.7 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 BST2 PF16716.5 ORY36268.1 - 0.0045 17.5 2.7 0.0057 17.2 2.7 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 GAS PF13851.6 ORY36268.1 - 0.0045 16.4 2.4 0.0051 16.2 2.4 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding CCCAP PF15964.5 ORY36268.1 - 0.0056 15.0 1.6 0.0063 14.9 1.6 1.0 1 0 0 1 1 1 1 Centrosomal colon cancer autoantigen protein family Spc29 PF17082.5 ORY36268.1 - 0.0066 16.3 0.6 0.0071 16.2 0.6 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 Herpes_UL6 PF01763.16 ORY36268.1 - 0.0074 14.9 0.9 0.008 14.8 0.9 1.0 1 0 0 1 1 1 1 Herpesvirus UL6 like CCDC92 PF14916.6 ORY36268.1 - 0.021 14.6 3.4 0.04 13.7 3.2 1.6 1 1 0 1 1 1 0 Coiled-coil domain of unknown function YabA PF06156.13 ORY36268.1 - 0.027 15.1 1.2 0.031 14.9 1.2 1.1 1 0 0 1 1 1 0 Initiation control protein YabA TMF_DNA_bd PF12329.8 ORY36268.1 - 0.03 14.3 1.9 0.044 13.8 1.2 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 ORY36268.1 - 0.041 14.4 1.0 0.044 14.3 1.0 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region Cluap1 PF10234.9 ORY36268.1 - 0.041 13.3 1.3 0.052 13.0 1.3 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF4477 PF14780.6 ORY36268.1 - 0.066 12.8 0.5 0.084 12.5 0.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4477) Fmp27_WPPW PF10359.9 ORY36268.1 - 0.085 11.7 2.0 0.099 11.5 2.0 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF948 PF06103.11 ORY36268.1 - 0.1 12.9 0.3 0.15 12.3 0.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) XhlA PF10779.9 ORY36268.1 - 0.16 12.2 1.3 0.26 11.5 1.3 1.3 1 0 0 1 1 1 0 Haemolysin XhlA USP8_interact PF08941.10 ORY36268.1 - 0.17 11.7 1.9 0.19 11.5 1.9 1.2 1 0 0 1 1 1 0 USP8 interacting Syntaxin_2 PF14523.6 ORY36268.1 - 0.18 12.2 4.8 0.44 10.9 4.8 1.7 1 1 0 1 1 1 0 Syntaxin-like protein SlyX PF04102.12 ORY36268.1 - 0.34 11.6 4.7 2.9 8.6 4.7 2.1 1 1 0 1 1 1 0 SlyX DivIC PF04977.15 ORY36268.1 - 0.78 9.6 4.2 3.4 7.5 4.2 1.9 1 1 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 ORY36268.1 - 1.5 8.9 3.9 4.5 7.4 1.1 2.2 1 1 1 2 2 2 0 Basic region leucine zipper Na_H_Exchanger PF00999.21 ORY36269.1 - 2.5e-24 85.8 14.0 3e-24 85.6 14.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 ORY36269.1 - 0.0053 16.8 0.1 0.0053 16.8 0.1 2.4 2 1 0 2 2 2 1 YrhC-like protein DUF4380 PF14315.6 ORY36269.1 - 0.14 11.1 0.1 0.19 10.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4380) DHHC PF01529.20 ORY36269.1 - 2.1 8.5 4.3 0.81 9.8 0.4 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase Methyltransf_21 PF05050.12 ORY36270.1 - 5.4e-08 33.1 0.0 9.3e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_21 PF05050.12 ORY36271.1 - 4.9e-08 33.2 0.1 6.5e-08 32.8 0.1 1.3 1 1 0 1 1 1 1 Methyltransferase FkbM domain ProRS-C_1 PF09180.11 ORY36272.1 - 1.4e-22 79.6 1.0 3.9e-22 78.2 1.0 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 ORY36272.1 - 3.7e-20 72.6 0.0 1.4e-19 70.7 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ORY36272.1 - 2.7e-15 56.3 0.0 5.6e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain DEAD PF00270.29 ORY36273.1 - 5.7e-47 159.7 0.0 1.2e-46 158.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY36273.1 - 2.4e-33 114.8 0.2 2.2e-30 105.3 0.0 3.2 2 1 1 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 ORY36273.1 - 2.7e-06 27.5 0.7 2.2e-05 24.6 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Ndc1_Nup PF09531.10 ORY36273.1 - 4.1 6.0 5.1 5.3 5.6 5.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ATP11 PF06644.11 ORY36273.1 - 9.2 6.0 15.8 17 5.1 15.8 1.4 1 0 0 1 1 1 0 ATP11 protein ProRS-C_1 PF09180.11 ORY36275.1 - 3.4e-23 81.6 0.9 9.8e-23 80.2 0.9 1.9 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 ORY36275.1 - 6.6e-20 71.8 0.0 2.3e-19 70.0 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ORY36275.1 - 3.9e-15 55.8 0.0 8.2e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Ribosomal_60s PF00428.19 ORY36275.1 - 0.39 11.3 11.4 0.1 13.2 5.9 2.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein MtN3_slv PF03083.16 ORY36276.1 - 9e-28 96.1 12.3 2.4e-21 75.6 1.0 2.6 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange Babuvirus_MP PF07234.11 ORY36276.1 - 0.32 11.2 1.1 0.55 10.4 1.1 1.3 1 0 0 1 1 1 0 Movement and RNA silencing protein Clr2_transil PF16761.5 ORY36278.1 - 7.6e-17 61.9 0.7 1.4e-16 61.0 0.7 1.4 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Asp_Glu_race_2 PF14669.6 ORY36278.1 - 0.075 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative aspartate racemase Coprogen_oxidas PF01218.18 ORY36281.1 - 4.5e-130 432.7 0.1 5.3e-130 432.4 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase DAP3 PF10236.9 ORY36282.1 - 1.5e-39 136.0 0.1 2.9e-39 135.1 0.1 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 FtsH_ext PF06480.15 ORY36282.1 - 7.9 6.9 7.0 2.5 8.5 0.1 2.6 3 0 0 3 3 3 0 FtsH Extracellular Septin PF00735.18 ORY36283.1 - 4.2e-98 328.1 0.1 7.7e-98 327.2 0.1 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 ORY36283.1 - 6.6e-08 32.6 0.1 1.5e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY36283.1 - 5.6e-06 26.4 0.0 0.00037 20.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 ORY36283.1 - 1.8e-05 24.4 0.2 0.0077 15.8 0.0 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 ORY36283.1 - 0.00024 20.5 0.1 0.00075 18.9 0.0 1.8 2 0 0 2 2 2 1 AIG1 family Pox_A32 PF04665.12 ORY36283.1 - 0.00042 19.8 0.0 0.00096 18.7 0.0 1.6 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_22 PF13401.6 ORY36283.1 - 0.0027 18.0 0.0 0.0067 16.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain IIGP PF05049.13 ORY36283.1 - 0.011 14.9 0.1 0.038 13.0 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 ORY36283.1 - 0.018 15.2 0.0 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 ORY36283.1 - 0.027 15.0 2.5 6 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ORY36283.1 - 0.03 14.7 0.1 0.069 13.5 0.0 1.7 2 0 0 2 2 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 ORY36283.1 - 0.039 13.3 0.6 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 ORY36283.1 - 0.083 12.6 0.9 0.13 11.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 ORY36283.1 - 0.084 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 ORY36283.1 - 0.16 12.5 0.1 0.97 10.0 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.23 ORY36283.1 - 0.24 11.4 8.0 1.2 9.2 0.1 3.0 2 1 1 3 3 3 0 Dynamin family DUF3287 PF11690.8 ORY36283.1 - 1.2 8.9 5.3 0.21 11.3 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) CBF PF03914.17 ORY36285.1 - 6.7e-31 107.6 2.0 6.7e-31 107.6 2.0 1.8 2 0 0 2 2 2 1 CBF/Mak21 family PBP1_TM PF14812.6 ORY36285.1 - 0.00012 22.3 0.4 0.00024 21.4 0.4 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal PEX-2N PF09263.10 ORY36285.1 - 0.1 13.0 0.1 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal SLAIN PF15301.6 ORY36285.1 - 0.16 11.2 0.1 0.27 10.4 0.1 1.3 1 0 0 1 1 1 0 SLAIN motif-containing family DUF4611 PF15387.6 ORY36285.1 - 1.1 9.5 3.9 2.5 8.4 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Porin_3 PF01459.22 ORY36286.1 - 0.05 13.0 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic porin Kinesin PF00225.23 ORY36287.1 - 3.2e-107 358.3 0.2 3.6e-107 358.1 0.2 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY36287.1 - 4.1e-26 91.7 0.0 9.4e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding Ilar_coat PF01787.16 ORY36289.1 - 5.3 6.8 13.5 0.2 11.4 0.8 2.3 2 0 0 2 2 2 0 Ilarvirus coat protein DUF5582 PF17819.1 ORY36290.1 - 8.7e-05 23.0 0.1 0.00015 22.2 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5582) EF-hand_7 PF13499.6 ORY36290.1 - 0.00035 21.0 0.0 0.00074 19.9 0.0 1.6 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 ORY36290.1 - 0.00047 19.5 0.1 0.0012 18.3 0.0 1.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 ORY36290.1 - 0.001 18.8 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 ORY36290.1 - 0.0023 17.8 0.0 0.014 15.2 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair DUF5586 PF17824.1 ORY36290.1 - 0.037 13.1 0.1 0.046 12.8 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5586) Dpy-30 PF05186.13 ORY36290.1 - 0.037 13.7 0.1 0.058 13.1 0.1 1.3 1 0 0 1 1 1 0 Dpy-30 motif UQ_con PF00179.26 ORY36291.1 - 6.5e-31 106.9 0.1 7.8e-31 106.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ank_2 PF12796.7 ORY36292.1 - 2.1e-12 47.5 1.2 0.00029 21.4 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY36292.1 - 4.7e-07 30.2 0.9 0.055 14.1 0.1 5.0 3 2 2 5 5 4 2 Ankyrin repeats (many copies) zf-RING_UBOX PF13445.6 ORY36292.1 - 6.4e-07 29.3 10.4 1.9e-06 27.8 10.4 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Ank_3 PF13606.6 ORY36292.1 - 1.2e-06 28.3 3.5 0.87 10.4 0.0 7.4 8 0 0 8 8 5 1 Ankyrin repeat zf-RING_2 PF13639.6 ORY36292.1 - 1.8e-06 28.2 12.3 1.8e-06 28.2 12.3 2.2 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 ORY36292.1 - 2e-05 24.7 12.2 2e-05 24.7 12.2 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Ank_5 PF13857.6 ORY36292.1 - 3.6e-05 24.0 4.5 3.5 8.0 0.1 6.1 5 1 1 6 6 6 1 Ankyrin repeats (many copies) zf-C3HC4 PF00097.25 ORY36292.1 - 3.6e-05 23.5 12.7 3.6e-05 23.5 12.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY36292.1 - 4.1e-05 23.4 10.4 4.1e-05 23.4 10.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY36292.1 - 0.0015 18.4 12.6 0.0015 18.4 12.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY36292.1 - 0.0015 18.4 11.2 0.0015 18.4 11.2 2.3 3 0 0 3 3 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 ORY36292.1 - 0.04 14.0 2.5 0.11 12.6 2.5 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 ORY36292.1 - 0.049 13.5 13.4 0.66 9.9 13.2 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 ORY36292.1 - 0.16 11.8 2.6 0.51 10.2 0.0 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_11 PF17123.5 ORY36292.1 - 0.22 11.3 8.4 0.66 9.8 8.4 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 ORY36292.1 - 0.47 10.8 5.8 1.3 9.3 5.8 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain CoA_transf_3 PF02515.17 ORY36293.1 - 4.9e-128 427.4 0.0 5.5e-128 427.2 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III SAM_4 PF18017.1 ORY36293.1 - 0.018 15.0 0.0 0.068 13.1 0.0 2.0 2 1 0 2 2 2 0 SAM domain (Sterile alpha motif) Pox_F16 PF04708.12 ORY36294.1 - 0.14 11.6 3.2 0.94 8.9 1.8 2.4 2 0 0 2 2 2 0 Poxvirus F16 protein Tcp10_C PF07202.13 ORY36295.1 - 1.8e-28 99.6 0.2 1.8e-28 99.6 0.2 1.7 2 0 0 2 2 2 1 T-complex protein 10 C-terminus DUF1515 PF07439.11 ORY36295.1 - 0.21 11.6 1.8 0.7 9.9 1.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) HAD_SAK_1 PF10307.9 ORY36296.1 - 4.3e-30 105.0 0.0 6.8e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins PGK PF00162.19 ORY36296.1 - 0.0056 15.7 0.1 0.046 12.7 0.0 2.0 2 0 0 2 2 2 1 Phosphoglycerate kinase DUF2683 PF10884.8 ORY36296.1 - 0.034 14.4 0.3 10 6.5 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) IQ PF00612.27 ORY36298.1 - 1.5e-05 24.3 10.3 0.00021 20.8 0.8 4.4 3 1 1 4 4 4 2 IQ calmodulin-binding motif Glyco_transf_88 PF16849.5 ORY36298.1 - 0.0039 16.2 0.0 0.0082 15.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 88 GerPC PF10737.9 ORY36298.1 - 0.028 14.5 0.8 0.028 14.5 0.8 1.7 2 0 0 2 2 2 0 Spore germination protein GerPC DUF4812 PF16071.5 ORY36298.1 - 0.051 13.4 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4812) DUF4554 PF15091.6 ORY36298.1 - 0.97 8.2 4.4 1.5 7.6 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Ank_2 PF12796.7 ORY36300.1 - 4.6e-08 33.5 0.2 0.0027 18.3 0.0 3.5 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY36300.1 - 1.7e-06 27.9 0.1 36 5.4 0.0 6.2 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 ORY36300.1 - 3.6e-05 24.2 0.1 3 8.6 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 ORY36300.1 - 0.029 14.3 0.1 0.078 12.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) F-box-like PF12937.7 ORY36300.1 - 0.031 14.2 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 F-box-like Zds_C PF08632.10 ORY36301.1 - 1.8e-16 59.6 0.5 3.6e-16 58.7 0.5 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term CMS1 PF14617.6 ORY36301.1 - 0.81 9.0 4.0 1.4 8.2 4.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Elong-fact-P_C PF09285.11 ORY36302.1 - 5.8e-12 45.2 0.5 1.3e-11 44.1 0.5 1.6 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP PF01132.20 ORY36302.1 - 2.6e-07 30.6 0.2 4.5e-07 29.8 0.2 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain EFP_N PF08207.12 ORY36302.1 - 8.2e-07 29.0 0.1 7.1e-06 26.0 0.1 2.4 1 1 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain RhoGAP PF00620.27 ORY36303.1 - 3.1e-47 160.2 0.0 7.5e-47 158.9 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 ORY36303.1 - 2.4e-15 56.6 0.1 8.7e-15 54.8 0.1 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Mating_N PF12731.7 ORY36303.1 - 0.087 12.9 0.1 0.46 10.6 0.1 2.3 2 0 0 2 2 2 0 Mating-type protein beta 1 HEAT_2 PF13646.6 ORY36305.1 - 1.9e-20 73.0 0.4 0.0015 18.9 0.0 10.3 9 1 1 10 10 10 5 HEAT repeats HEAT PF02985.22 ORY36305.1 - 4.8e-08 32.6 13.6 27 5.4 0.0 11.9 14 0 0 14 14 13 0 HEAT repeat HEAT_EZ PF13513.6 ORY36305.1 - 2.5e-06 27.8 4.0 0.37 11.3 0.0 8.6 9 0 0 9 9 9 1 HEAT-like repeat UME PF08064.13 ORY36305.1 - 0.0078 16.1 0.7 0.21 11.5 0.0 3.8 4 0 0 4 4 4 1 UME (NUC010) domain RTP1_C1 PF10363.9 ORY36305.1 - 0.019 15.2 0.8 45 4.3 0.0 4.9 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Rif1_N PF12231.8 ORY36305.1 - 0.03 13.3 0.3 0.11 11.4 0.3 2.0 1 1 0 1 1 1 0 Rap1-interacting factor 1 N terminal Nipped-B_C PF12830.7 ORY36305.1 - 0.085 12.8 0.0 5.4 6.9 0.0 3.4 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus PC_rep PF01851.22 ORY36305.1 - 0.15 12.6 0.0 1.4 9.5 0.0 2.9 1 0 0 1 1 1 0 Proteasome/cyclosome repeat Cnd1 PF12717.7 ORY36305.1 - 0.25 11.4 9.1 2.4 8.2 0.0 5.9 6 2 1 7 7 7 0 non-SMC mitotic condensation complex subunit 1 IFRD PF05004.13 ORY36305.1 - 0.28 10.2 3.8 8.3 5.4 0.1 4.4 5 0 0 5 5 5 0 Interferon-related developmental regulator (IFRD) RICTOR_M PF14666.6 ORY36305.1 - 1 9.2 4.4 6.7 6.5 0.1 4.0 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, middle domain IF4E PF01652.18 ORY36306.1 - 1.7e-52 177.4 1.7 2.1e-52 177.1 1.7 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Glyco_transf_90 PF05686.12 ORY36307.1 - 1.3e-22 80.3 1.0 2.7e-21 76.0 0.7 2.5 2 1 0 2 2 2 1 Glycosyl transferase family 90 DUF3446 PF11928.8 ORY36307.1 - 0.0069 16.7 5.7 0.015 15.5 5.7 1.5 1 0 0 1 1 1 1 Early growth response N-terminal domain Glyco_trans_1_2 PF13524.6 ORY36307.1 - 0.073 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 WD40 PF00400.32 ORY36308.1 - 5e-60 198.1 21.7 4.9e-10 39.8 0.5 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY36308.1 - 1.2e-22 79.9 0.3 0.0033 17.7 0.0 6.1 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY36308.1 - 1.6e-12 47.7 0.0 1.3e-07 31.7 0.0 3.7 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY36308.1 - 1.9e-07 30.7 0.0 3e-05 23.5 0.0 3.2 1 1 2 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 ORY36308.1 - 9.9e-07 28.0 2.3 0.016 14.2 0.0 4.1 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORY36308.1 - 2.5e-06 26.4 18.9 0.044 12.4 0.1 6.1 2 1 4 7 7 6 4 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 ORY36308.1 - 0.00033 19.7 0.2 0.066 12.1 0.0 3.0 1 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 ORY36308.1 - 0.00051 18.5 0.0 0.0089 14.4 0.0 2.1 1 1 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz VID27 PF08553.10 ORY36308.1 - 0.0024 17.0 0.0 0.14 11.2 0.0 2.9 2 1 1 3 3 3 2 VID27 C-terminal WD40-like domain CDC45 PF02724.14 ORY36308.1 - 0.012 13.9 32.2 0.019 13.3 32.2 1.4 1 0 0 1 1 1 0 CDC45-like protein PD40 PF07676.12 ORY36308.1 - 0.013 15.4 0.1 1.1 9.3 0.1 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Presenilin PF01080.17 ORY36308.1 - 0.11 11.2 28.5 0.16 10.7 28.5 1.2 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 ORY36308.1 - 0.54 8.5 35.9 0.64 8.2 35.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIF_alpha PF05793.12 ORY36308.1 - 0.84 8.1 34.9 1.1 7.7 34.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Borrelia_P83 PF05262.11 ORY36308.1 - 3.2 6.1 23.7 4.2 5.8 23.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein SDA1 PF05285.12 ORY36308.1 - 3.7 6.9 46.9 5.1 6.4 46.9 1.1 1 0 0 1 1 1 0 SDA1 Dsh_C PF12316.8 ORY36308.1 - 4 7.8 17.6 6.5 7.1 17.6 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Nop14 PF04147.12 ORY36308.1 - 6.3 4.9 41.8 8.5 4.4 41.8 1.1 1 0 0 1 1 1 0 Nop14-like family Raftlin PF15250.6 ORY36308.1 - 7.2 5.2 23.2 9.6 4.8 23.2 1.2 1 0 0 1 1 1 0 Raftlin Homeodomain PF00046.29 ORY36309.1 - 3.7e-58 193.2 10.9 8.3e-12 44.8 0.4 5.3 5 0 0 5 5 5 5 Homeodomain Homeobox_KN PF05920.11 ORY36309.1 - 2.2e-17 62.6 3.2 0.0016 18.3 0.0 5.6 5 0 0 5 5 5 5 Homeobox KN domain Homez PF11569.8 ORY36309.1 - 1.6e-16 59.5 1.7 0.056 12.9 0.0 5.4 5 0 0 5 5 5 5 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 ORY36309.1 - 2.2e-06 27.5 1.4 0.53 10.2 0.0 5.4 6 0 0 6 6 6 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MerR PF00376.23 ORY36309.1 - 0.00016 21.3 0.0 11 5.8 0.0 4.5 5 0 0 5 5 5 1 MerR family regulatory protein MerR_1 PF13411.6 ORY36309.1 - 0.00023 21.2 1.7 35 4.6 0.0 5.2 5 0 0 5 5 5 0 MerR HTH family regulatory protein HTH_26 PF13443.6 ORY36309.1 - 0.00039 20.8 5.0 14 6.2 0.0 4.7 5 0 0 5 5 5 1 Cro/C1-type HTH DNA-binding domain HTH_28 PF13518.6 ORY36309.1 - 0.0049 17.0 0.2 0.77 9.9 0.0 3.9 4 0 0 4 4 4 1 Helix-turn-helix domain Terminase_5 PF06056.12 ORY36309.1 - 0.034 14.0 0.9 1.3 9.0 0.1 2.8 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) HTH_36 PF13730.6 ORY36309.1 - 0.035 14.0 0.0 17 5.5 0.0 3.8 4 0 0 4 4 4 0 Helix-turn-helix domain LcrG PF07216.12 ORY36309.1 - 0.047 13.6 0.9 1 9.3 1.1 2.5 2 0 0 2 2 2 0 LcrG protein Spt20 PF12090.8 ORY36309.1 - 0.11 12.1 7.8 0.19 11.3 7.8 1.3 1 0 0 1 1 1 0 Spt20 family Sigma70_r4_2 PF08281.12 ORY36309.1 - 0.16 11.7 0.2 26 4.6 0.0 3.7 4 0 0 4 4 4 0 Sigma-70, region 4 Rhodanese PF00581.20 ORY36310.1 - 2.8e-11 43.9 0.0 5.4e-11 43.0 0.0 1.5 1 1 0 1 1 1 1 Rhodanese-like domain EF_assoc_2 PF08356.12 ORY36311.1 - 1.4e-36 124.3 0.0 9.3e-36 121.7 0.0 2.2 2 0 0 2 2 2 1 EF hand associated EF_assoc_1 PF08355.12 ORY36311.1 - 3.1e-29 100.4 1.0 5.9e-29 99.5 1.0 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 ORY36311.1 - 9.4e-29 100.1 0.0 2.4e-22 79.2 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 ORY36311.1 - 3.6e-14 53.0 0.0 4.9e-10 39.7 0.0 3.2 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORY36311.1 - 3e-10 40.2 0.0 0.00015 21.8 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_6 PF13405.6 ORY36311.1 - 9.6e-08 31.4 0.8 0.014 15.2 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 ORY36311.1 - 1.6e-07 31.6 0.1 0.0015 19.0 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORY36311.1 - 1.3e-06 27.5 3.5 0.0097 15.4 0.2 2.6 2 0 0 2 2 2 2 EF hand AAA_22 PF13401.6 ORY36311.1 - 1e-05 25.8 0.0 0.21 11.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 ORY36311.1 - 1.4e-05 25.6 0.0 0.13 12.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 ORY36311.1 - 2.6e-05 24.4 0.0 0.26 11.3 0.0 3.3 2 1 0 3 3 3 2 Dynamin family EF-hand_10 PF14788.6 ORY36311.1 - 5.1e-05 23.0 2.5 0.0033 17.3 0.2 2.5 2 0 0 2 2 2 1 EF hand AAA_16 PF13191.6 ORY36311.1 - 0.00017 22.0 0.0 0.95 9.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain SRPRB PF09439.10 ORY36311.1 - 0.00017 21.0 0.0 0.3 10.5 0.0 2.4 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Arf PF00025.21 ORY36311.1 - 0.0006 19.3 0.2 0.14 11.6 0.2 3.0 2 2 0 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ORY36311.1 - 0.00091 19.2 0.3 3.7 7.4 0.0 3.4 2 1 1 3 3 3 1 RsgA GTPase EF-hand_8 PF13833.6 ORY36311.1 - 0.001 18.9 2.4 0.44 10.4 0.2 2.8 2 0 0 2 2 2 2 EF-hand domain pair ABC_tran PF00005.27 ORY36311.1 - 0.0013 19.2 0.0 0.38 11.3 0.0 2.6 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 ORY36311.1 - 0.0013 18.4 0.1 2.6 7.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.22 ORY36311.1 - 0.0033 17.8 0.0 2.8 8.4 0.0 2.7 2 0 0 2 2 2 1 RNA helicase GTP_EFTU PF00009.27 ORY36311.1 - 0.0035 16.9 1.6 1.8 8.0 0.1 3.5 3 1 0 4 4 4 1 Elongation factor Tu GTP binding domain AAA PF00004.29 ORY36311.1 - 0.0044 17.4 0.0 3 8.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 ORY36311.1 - 0.0076 15.6 0.0 1.2 8.3 0.0 2.6 2 0 0 2 2 2 1 Septin AAA_24 PF13479.6 ORY36311.1 - 0.011 15.5 0.0 4.8 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ORY36311.1 - 0.026 14.8 0.0 0.8 9.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 ORY36311.1 - 0.027 14.1 0.7 0.69 9.5 0.0 3.2 3 1 1 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 ORY36311.1 - 0.035 14.1 0.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 ORY36311.1 - 0.037 13.7 0.0 9.5 5.9 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase EF-hand_5 PF13202.6 ORY36311.1 - 0.038 13.5 5.7 2.6 7.7 0.4 2.8 2 0 0 2 2 2 0 EF hand AAA_14 PF13173.6 ORY36311.1 - 0.057 13.4 0.0 7.2 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 ORY36311.1 - 0.06 13.1 0.1 6.5 6.5 0.0 3.2 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 ORY36311.1 - 0.067 12.3 0.0 20 4.2 0.0 3.1 3 0 0 3 3 3 0 G-protein alpha subunit AAA_7 PF12775.7 ORY36311.1 - 0.072 12.6 0.0 2.6 7.5 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 ORY36311.1 - 0.076 12.9 0.0 3.8 7.4 0.0 2.6 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 ORY36311.1 - 0.13 12.2 0.0 0.55 10.1 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 ORY36311.1 - 0.13 11.7 0.1 1.8 7.9 0.0 2.5 3 0 0 3 3 2 0 Bacterial TniB protein AAA_33 PF13671.6 ORY36311.1 - 0.14 12.3 0.0 26 5.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain SPARC_Ca_bdg PF10591.9 ORY36311.1 - 0.15 12.4 0.2 31 4.9 0.0 2.8 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF815 PF05673.13 ORY36311.1 - 0.16 11.1 0.0 17 4.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 ORY36311.1 - 0.17 11.2 0.1 3.6 6.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Cation_ATPase_C PF00689.21 ORY36312.1 - 2.5e-08 33.8 11.4 7.7e-08 32.3 11.4 1.9 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY36312.1 - 0.0041 17.4 0.0 0.43 10.8 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase MAAL_C PF07476.11 ORY36312.1 - 0.093 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus WD40 PF00400.32 ORY36313.1 - 2.1e-14 53.7 9.4 0.021 15.7 0.1 7.0 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY36313.1 - 1.3e-06 28.6 0.3 1.6 9.1 0.1 6.1 2 1 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY36313.1 - 0.0049 15.9 0.1 1.6 7.6 0.0 2.9 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Tet_JBP PF12851.7 ORY36313.1 - 0.023 14.1 0.0 0.29 10.4 0.0 2.1 1 1 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily PTPRCAP PF15713.5 ORY36313.1 - 2.1 8.6 10.2 3.7 7.8 10.2 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated EF_assoc_2 PF08356.12 ORY36314.1 - 1.7e-36 124.1 0.0 1.1e-35 121.5 0.0 2.1 2 0 0 2 2 2 1 EF hand associated EF_assoc_1 PF08355.12 ORY36314.1 - 3.1e-29 100.4 1.0 6.7e-29 99.3 1.0 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 ORY36314.1 - 1.3e-28 99.7 0.0 2.9e-22 79.0 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 ORY36314.1 - 4.9e-14 52.6 0.0 5.6e-10 39.5 0.0 3.1 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORY36314.1 - 4e-10 39.8 0.0 0.00017 21.6 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_6 PF13405.6 ORY36314.1 - 1.2e-07 31.1 0.8 0.016 15.1 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 ORY36314.1 - 2.1e-07 31.3 0.1 0.0016 18.8 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORY36314.1 - 1.6e-06 27.2 3.5 0.011 15.3 0.2 2.6 2 0 0 2 2 2 2 EF hand AAA_22 PF13401.6 ORY36314.1 - 1.4e-05 25.4 0.0 0.24 11.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 ORY36314.1 - 1.9e-05 25.2 0.0 0.14 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 ORY36314.1 - 3.4e-05 24.0 0.0 0.28 11.2 0.0 3.2 2 1 0 3 3 3 2 Dynamin family EF-hand_10 PF14788.6 ORY36314.1 - 6.2e-05 22.8 2.5 0.0036 17.1 0.2 2.5 2 0 0 2 2 2 1 EF hand SRPRB PF09439.10 ORY36314.1 - 0.00018 21.0 0.0 0.34 10.3 0.0 2.4 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 ORY36314.1 - 0.00018 21.9 0.0 1 9.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain Arf PF00025.21 ORY36314.1 - 0.00052 19.5 0.2 0.11 12.0 0.1 3.0 2 2 0 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ORY36314.1 - 0.00099 19.0 0.2 3.2 7.6 0.0 3.4 2 1 1 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 ORY36314.1 - 0.0011 18.6 0.0 1.8 8.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain EF-hand_8 PF13833.6 ORY36314.1 - 0.0012 18.6 2.4 0.49 10.3 0.2 2.8 2 0 0 2 2 2 1 EF-hand domain pair ABC_tran PF00005.27 ORY36314.1 - 0.0015 19.1 0.0 0.42 11.1 0.0 2.6 2 0 0 2 2 2 1 ABC transporter GTP_EFTU PF00009.27 ORY36314.1 - 0.0019 17.8 1.4 3.7 7.1 1.3 3.5 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain RNA_helicase PF00910.22 ORY36314.1 - 0.0042 17.5 0.0 3.1 8.2 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 ORY36314.1 - 0.0055 17.1 0.0 3.4 8.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Septin PF00735.18 ORY36314.1 - 0.0078 15.5 0.0 1.2 8.4 0.0 2.6 2 0 0 2 2 2 1 Septin AAA_24 PF13479.6 ORY36314.1 - 0.012 15.4 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 ORY36314.1 - 0.027 14.5 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 ORY36314.1 - 0.031 13.9 0.6 0.77 9.3 0.0 3.2 3 1 1 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 ORY36314.1 - 0.032 14.5 0.0 0.89 9.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 ORY36314.1 - 0.046 13.4 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase EF-hand_5 PF13202.6 ORY36314.1 - 0.048 13.2 5.7 2.9 7.6 0.4 2.7 2 0 0 2 2 2 0 EF hand G-alpha PF00503.20 ORY36314.1 - 0.048 12.8 0.0 22 4.0 0.0 3.1 3 0 0 3 3 3 0 G-protein alpha subunit AAA_7 PF12775.7 ORY36314.1 - 0.067 12.7 0.0 2.5 7.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 ORY36314.1 - 0.069 12.9 0.1 7.3 6.3 0.0 3.2 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 ORY36314.1 - 0.07 13.2 0.0 8.1 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ORY36314.1 - 0.094 12.6 0.0 4.2 7.2 0.0 2.6 2 0 0 2 2 2 0 NACHT domain TniB PF05621.11 ORY36314.1 - 0.12 11.7 0.1 1.7 8.0 0.0 2.4 3 0 0 3 3 2 0 Bacterial TniB protein NB-ARC PF00931.22 ORY36314.1 - 0.12 11.5 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 ORY36314.1 - 0.15 12.0 0.0 0.61 9.9 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF815 PF05673.13 ORY36314.1 - 0.16 11.1 0.0 17 4.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 ORY36314.1 - 0.17 12.0 0.0 28 4.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 ORY36314.1 - 0.18 11.1 0.1 4 6.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DAP3 PF10236.9 ORY36314.1 - 0.2 10.8 0.1 0.74 8.9 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Rhodanese PF00581.20 ORY36315.1 - 2.3e-11 44.1 0.0 4.3e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Homeodomain PF00046.29 ORY36316.1 - 2.3e-57 190.7 11.3 9.8e-12 44.5 0.4 5.3 5 0 0 5 5 5 5 Homeodomain Homeobox_KN PF05920.11 ORY36316.1 - 3.8e-18 65.1 3.0 0.00012 21.9 0.0 5.5 5 0 0 5 5 5 4 Homeobox KN domain Homez PF11569.8 ORY36316.1 - 1.1e-14 53.7 1.7 0.066 12.7 0.0 5.4 5 0 0 5 5 5 5 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 ORY36316.1 - 2.9e-08 33.4 3.2 0.62 10.0 0.0 5.8 6 0 0 6 6 6 2 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT MerR PF00376.23 ORY36316.1 - 1.9e-06 27.5 0.1 10 6.0 0.0 5.1 5 0 0 5 5 5 0 MerR family regulatory protein HTH_26 PF13443.6 ORY36316.1 - 6.3e-06 26.5 4.7 3.1 8.3 0.0 5.2 5 0 0 5 5 5 1 Cro/C1-type HTH DNA-binding domain Sigma70_r4 PF04545.16 ORY36316.1 - 1e-05 24.9 0.0 1.6 8.3 0.0 4.8 5 0 0 5 5 5 2 Sigma-70, region 4 HTH_28 PF13518.6 ORY36316.1 - 3.2e-05 24.0 0.1 0.9 9.7 0.0 4.7 5 0 0 5 5 4 1 Helix-turn-helix domain MerR_1 PF13411.6 ORY36316.1 - 4.5e-05 23.5 3.7 4.4 7.5 0.1 5.2 5 0 0 5 5 5 1 MerR HTH family regulatory protein Sigma70_r4_2 PF08281.12 ORY36316.1 - 0.00014 21.5 0.3 7 6.4 0.0 4.9 5 0 0 5 5 5 1 Sigma-70, region 4 HTH_36 PF13730.6 ORY36316.1 - 0.0033 17.4 0.0 11 6.0 0.0 3.8 4 0 0 4 4 3 0 Helix-turn-helix domain HTH_23 PF13384.6 ORY36316.1 - 0.0048 16.7 4.9 8.4 6.3 0.1 4.5 5 0 0 5 5 5 1 Homeodomain-like domain Phage_CI_repr PF07022.13 ORY36316.1 - 0.0063 16.6 0.1 1.6 8.8 0.0 3.5 3 0 0 3 3 3 1 Bacteriophage CI repressor helix-turn-helix domain HTH_24 PF13412.6 ORY36316.1 - 0.0083 15.7 1.6 19 4.9 0.0 5.2 6 0 0 6 6 5 0 Winged helix-turn-helix DNA-binding HTH_17 PF12728.7 ORY36316.1 - 0.028 14.6 3.7 16 5.7 0.1 4.7 5 0 0 5 5 5 0 Helix-turn-helix domain Terminase_5 PF06056.12 ORY36316.1 - 0.044 13.7 3.7 1.5 8.8 0.1 3.4 3 0 0 3 3 3 0 Putative ATPase subunit of terminase (gpP-like) LcrG PF07216.12 ORY36316.1 - 0.053 13.4 0.9 1.3 9.0 1.2 2.6 2 0 0 2 2 2 0 LcrG protein DUF1323 PF07037.11 ORY36316.1 - 0.86 10.0 6.6 11 6.4 0.1 4.3 4 0 0 4 4 4 0 Putative transcription regulator (DUF1323) GCIP PF13324.6 ORY36316.1 - 1.3 8.6 7.0 3.2 7.3 7.0 1.6 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting ORC3_N PF07034.11 ORY36316.1 - 2.9 6.9 14.4 2.8 7.0 0.4 3.9 4 0 0 4 4 4 0 Origin recognition complex (ORC) subunit 3 N-terminus Spt20 PF12090.8 ORY36316.1 - 9.5 5.8 15.5 0.24 11.0 7.8 2.0 2 0 0 2 2 2 0 Spt20 family Rad51 PF08423.11 ORY36317.1 - 9.5e-23 80.8 0.0 4e-12 45.9 0.0 3.4 2 2 0 2 2 2 2 Rad51 ATP-synt_J PF04911.12 ORY36317.1 - 0.0023 17.5 0.2 0.0061 16.1 0.2 1.7 1 0 0 1 1 1 1 ATP synthase j chain AAA_25 PF13481.6 ORY36317.1 - 0.0073 15.9 1.5 0.32 10.6 0.6 3.0 2 1 0 2 2 2 1 AAA domain RecA PF00154.21 ORY36317.1 - 0.03 13.8 0.1 5.5 6.4 0.0 2.9 3 0 0 3 3 3 0 recA bacterial DNA recombination protein NAM-associated PF14303.6 ORY36317.1 - 0.38 11.4 3.3 0.84 10.3 3.3 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain RIO1 PF01163.22 ORY36318.1 - 6.7e-11 42.1 0.0 9.5e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 ORY36318.1 - 4.9e-10 39.7 0.0 5.2e-06 26.6 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 ORY36318.1 - 3.8e-09 36.3 0.0 4.6e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 ORY36318.1 - 7.8e-08 31.9 0.0 1.4e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 ORY36318.1 - 3.9e-06 26.3 0.0 4.5e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.20 ORY36318.1 - 2.5e-05 23.7 0.0 3.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 ORY36318.1 - 0.00037 20.1 0.0 0.068 12.7 0.0 2.2 1 1 1 2 2 2 2 Choline/ethanolamine kinase WaaY PF06176.11 ORY36318.1 - 0.0024 17.6 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) TetR_C_29 PF17938.1 ORY36318.1 - 0.09 12.9 0.0 1 9.5 0.0 2.5 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Serinc PF03348.15 ORY36319.1 - 1.7e-136 455.5 14.8 2e-136 455.4 14.8 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF4231 PF14015.6 ORY36319.1 - 1.8 9.0 19.1 0.47 10.9 0.6 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF4231) HMG_box PF00505.19 ORY36320.1 - 4.9e-10 39.7 0.3 1.1e-09 38.6 0.3 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY36320.1 - 2e-07 31.5 0.2 5.7e-07 30.0 0.2 1.7 1 0 0 1 1 1 1 HMG-box domain FHA_2 PF17913.1 ORY36320.1 - 2.7e-07 30.7 0.0 5.4e-05 23.3 0.0 2.5 1 1 1 2 2 2 1 FHA domain DUF4611 PF15387.6 ORY36320.1 - 0.11 12.7 6.2 0.095 12.9 1.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) YABBY PF04690.13 ORY36320.1 - 0.18 12.3 6.3 0.23 12.0 5.1 1.8 1 1 0 1 1 1 0 YABBY protein Myc_N PF01056.18 ORY36320.1 - 0.35 10.7 10.0 0.23 11.3 5.7 2.3 2 0 0 2 2 2 0 Myc amino-terminal region DUF2052 PF09747.9 ORY36320.1 - 1.2 9.2 13.6 0.33 11.0 6.9 2.4 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) FAM176 PF14851.6 ORY36320.1 - 8.8 6.0 11.4 0.26 10.9 3.3 2.4 2 0 0 2 2 2 0 FAM176 family Ribosomal_S25 PF03297.15 ORY36321.1 - 4.9e-37 126.2 0.2 5.4e-37 126.0 0.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.7 ORY36321.1 - 0.015 15.1 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_CodY PF08222.11 ORY36321.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 CodY helix-turn-helix domain Ribosomal_L24e PF01246.20 ORY36322.1 - 2.5e-28 98.1 0.1 2.5e-28 98.1 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e FANC_SAP PF18081.1 ORY36322.1 - 0.31 11.2 3.9 0.29 11.3 1.7 2.0 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain Spem1 PF15670.5 ORY36322.1 - 0.44 10.1 3.9 0.49 9.9 3.9 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 Nup96 PF12110.8 ORY36323.1 - 1.6e-62 211.3 6.7 3.1e-61 207.0 6.7 2.2 1 1 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 ORY36323.1 - 8.6e-41 139.5 0.0 1.5e-40 138.8 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 ORY36323.1 - 7.9e-14 52.3 242.3 0.0022 18.8 30.4 10.1 3 2 5 8 8 8 6 Nucleoporin FG repeat region Sigma_1s PF02454.16 ORY36323.1 - 0.36 10.8 1.4 1.7 8.6 0.1 2.5 2 0 0 2 2 2 0 Sigma 1s protein ICMT PF04140.14 ORY36324.1 - 1.3e-21 76.8 0.5 1.6e-21 76.5 0.5 1.1 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 ORY36324.1 - 1.4e-07 31.9 0.5 1.6e-07 31.7 0.5 1.1 1 0 0 1 1 1 1 Phospholipid methyltransferase NnrU PF07298.11 ORY36324.1 - 0.0052 16.3 0.1 0.0073 15.8 0.1 1.2 1 0 0 1 1 1 1 NnrU protein ERG4_ERG24 PF01222.17 ORY36324.1 - 0.0074 15.1 0.4 0.0085 14.9 0.4 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 ORY36324.1 - 0.0092 15.5 0.1 0.011 15.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ATP_Ca_trans_C PF12424.8 ORY36325.1 - 0.0041 17.6 0.0 0.0073 16.8 0.0 1.4 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal ATP_Ca_trans_C PF12424.8 ORY36327.1 - 0.0041 17.6 0.0 0.0073 16.8 0.0 1.4 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal ATP_Ca_trans_C PF12424.8 ORY36329.1 - 0.0041 17.6 0.0 0.0073 16.8 0.0 1.4 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal ATP_Ca_trans_C PF12424.8 ORY36331.1 - 0.0041 17.6 0.0 0.0073 16.8 0.0 1.4 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal ATP_Ca_trans_C PF12424.8 ORY36333.1 - 0.0041 17.6 0.0 0.0073 16.8 0.0 1.4 1 0 0 1 1 1 1 Plasma membrane calcium transporter ATPase C terminal WD40 PF00400.32 ORY36334.1 - 2.6e-42 142.0 28.5 1.5e-08 35.1 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY36334.1 - 2.3e-11 43.8 1.9 0.051 13.9 0.0 5.0 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY36334.1 - 0.0001 21.1 6.7 0.037 12.7 0.2 3.9 1 1 3 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.12 ORY36334.1 - 0.00018 21.3 1.1 6.7 6.8 0.1 4.4 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 ORY36334.1 - 0.00075 18.6 1.0 2.7 6.9 0.2 4.0 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORY36334.1 - 0.003 16.1 0.0 1.4 7.3 0.0 2.7 1 1 2 3 3 3 3 Cytochrome D1 heme domain DUF1416 PF07210.12 ORY36334.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) Ribosomal_S4e PF00900.20 ORY36335.1 - 4.6e-37 125.8 0.4 9.8e-37 124.7 0.4 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 ORY36335.1 - 2.3e-26 91.1 0.1 4.2e-26 90.3 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 ORY36335.1 - 4.3e-17 61.9 5.0 8.6e-17 61.0 5.0 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 ORY36335.1 - 2.4e-07 30.3 0.0 4.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 ORY36335.1 - 1.1e-05 25.2 0.7 1.1e-05 25.2 0.7 2.5 3 0 0 3 3 3 1 KOW motif ComC PF03047.14 ORY36335.1 - 0.17 11.7 0.1 0.34 10.7 0.1 1.5 1 0 0 1 1 1 0 COMC family WD40 PF00400.32 ORY36337.1 - 1.2e-36 124.0 9.7 1.1e-09 38.7 0.1 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY36337.1 - 4.6e-14 52.5 0.0 3.1e-07 30.6 0.1 5.2 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 ORY36337.1 - 2.8e-12 45.9 2.6 5.5e-12 45.0 2.6 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Ge1_WD40 PF16529.5 ORY36337.1 - 0.0016 17.5 0.0 5.8 5.8 0.0 3.8 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ORY36337.1 - 0.064 12.6 0.0 0.37 10.1 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain MMS1_N PF10433.9 ORY36337.1 - 0.2 10.2 0.0 0.65 8.5 0.0 1.8 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ribosomal_S4e PF00900.20 ORY36338.1 - 4.6e-37 125.8 0.4 9.8e-37 124.7 0.4 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 ORY36338.1 - 2.3e-26 91.1 0.1 4.2e-26 90.3 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 ORY36338.1 - 4.3e-17 61.9 5.0 8.6e-17 61.0 5.0 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 ORY36338.1 - 2.4e-07 30.3 0.0 4.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 ORY36338.1 - 1.1e-05 25.2 0.7 1.1e-05 25.2 0.7 2.5 3 0 0 3 3 3 1 KOW motif ComC PF03047.14 ORY36338.1 - 0.17 11.7 0.1 0.34 10.7 0.1 1.5 1 0 0 1 1 1 0 COMC family DUF496 PF04363.12 ORY36339.1 - 0.15 12.1 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF496) Mur_ligase_M PF08245.12 ORY36340.1 - 7.6e-11 42.4 0.0 1.5e-10 41.4 0.0 1.6 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 ORY36340.1 - 0.00012 22.3 0.0 0.0017 18.5 0.0 2.3 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain ZirS_C PF16583.5 ORY36340.1 - 1 8.9 2.4 3.4 7.2 0.8 2.1 1 1 1 2 2 2 0 Zinc-regulated secreted antivirulence protein C-terminal domain MPP6 PF10175.9 ORY36341.1 - 0.002 18.6 10.2 0.0043 17.5 10.2 1.5 1 0 0 1 1 1 1 M-phase phosphoprotein 6 SDA1 PF05285.12 ORY36341.1 - 0.0032 16.9 12.7 0.0047 16.4 12.7 1.3 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 ORY36341.1 - 0.011 14.0 11.0 0.017 13.5 11.0 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 ORY36341.1 - 0.024 14.0 18.3 0.039 13.3 18.3 1.3 1 0 0 1 1 1 0 BUD22 DUF2052 PF09747.9 ORY36341.1 - 0.032 14.4 11.8 0.063 13.4 11.8 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Nop14 PF04147.12 ORY36341.1 - 0.033 12.4 17.8 0.051 11.8 17.8 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.12 ORY36341.1 - 0.057 12.0 15.1 0.084 11.5 15.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RXT2_N PF08595.11 ORY36341.1 - 0.12 12.4 10.1 0.24 11.4 10.1 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 ORY36341.1 - 0.15 10.1 18.2 0.29 9.2 18.2 1.4 1 0 0 1 1 1 0 DNA polymerase phi BSP_II PF05432.11 ORY36341.1 - 0.27 10.9 15.8 0.57 9.8 15.8 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) NOA36 PF06524.12 ORY36341.1 - 0.31 10.3 16.2 0.55 9.5 16.2 1.3 1 0 0 1 1 1 0 NOA36 protein RRN3 PF05327.11 ORY36341.1 - 1 7.8 13.1 1.5 7.3 13.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PGA2 PF07543.12 ORY36341.1 - 1.5 8.8 10.2 3.7 7.5 10.2 1.6 1 0 0 1 1 1 0 Protein trafficking PGA2 Spt5_N PF11942.8 ORY36341.1 - 1.6 9.8 20.9 5.3 8.1 20.9 1.8 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal TRAP_alpha PF03896.16 ORY36341.1 - 2.8 7.1 9.5 4.9 6.3 9.5 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit XAP5 PF04921.14 ORY36341.1 - 6.2 6.6 10.4 13 5.5 10.4 1.6 1 0 0 1 1 1 0 XAP5, circadian clock regulator FAM176 PF14851.6 ORY36341.1 - 6.7 6.4 12.3 14 5.3 12.3 1.5 1 0 0 1 1 1 0 FAM176 family GEN1_C PF18380.1 ORY36341.1 - 8 7.4 12.1 31 5.5 12.1 2.0 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain Ank_5 PF13857.6 ORY36342.1 - 1.1e-12 47.9 1.1 4.1e-08 33.3 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY36342.1 - 2e-10 41.1 0.8 1.6e-09 38.2 0.7 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY36342.1 - 1.2e-09 38.6 0.2 0.00069 20.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY36342.1 - 2.9e-08 33.3 2.3 0.00086 19.6 0.2 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 ORY36342.1 - 2e-07 31.1 6.9 4.1e-06 27.0 1.6 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ribosomal_S4e PF00900.20 ORY36343.1 - 4.6e-37 125.8 0.4 9.8e-37 124.7 0.4 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 ORY36343.1 - 2.3e-26 91.1 0.1 4.2e-26 90.3 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 ORY36343.1 - 4.3e-17 61.9 5.0 8.6e-17 61.0 5.0 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 ORY36343.1 - 2.4e-07 30.3 0.0 4.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 ORY36343.1 - 1.1e-05 25.2 0.7 1.1e-05 25.2 0.7 2.5 3 0 0 3 3 3 1 KOW motif ComC PF03047.14 ORY36343.1 - 0.17 11.7 0.1 0.34 10.7 0.1 1.5 1 0 0 1 1 1 0 COMC family WD40 PF00400.32 ORY36344.1 - 1.8e-36 123.5 9.7 1.2e-09 38.6 0.1 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY36344.1 - 5.7e-14 52.2 0.0 3.4e-07 30.4 0.1 5.2 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PRP4 PF08799.11 ORY36344.1 - 3e-12 45.8 2.6 5.8e-12 44.9 2.6 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Ge1_WD40 PF16529.5 ORY36344.1 - 0.0019 17.2 0.0 5.3 5.9 0.0 3.8 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ORY36344.1 - 0.071 12.4 0.0 0.39 10.0 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain MMS1_N PF10433.9 ORY36344.1 - 0.22 10.1 0.0 0.7 8.5 0.0 1.8 2 0 0 2 2 2 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ribosomal_S4e PF00900.20 ORY36345.1 - 4.6e-37 125.8 0.4 9.8e-37 124.7 0.4 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 ORY36345.1 - 2.3e-26 91.1 0.1 4.2e-26 90.3 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 ORY36345.1 - 4.3e-17 61.9 5.0 8.6e-17 61.0 5.0 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 ORY36345.1 - 2.4e-07 30.3 0.0 4.5e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 ORY36345.1 - 1.1e-05 25.2 0.7 1.1e-05 25.2 0.7 2.5 3 0 0 3 3 3 1 KOW motif ComC PF03047.14 ORY36345.1 - 0.17 11.7 0.1 0.34 10.7 0.1 1.5 1 0 0 1 1 1 0 COMC family WD40 PF00400.32 ORY36346.1 - 2.6e-42 142.0 28.5 1.5e-08 35.1 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY36346.1 - 2.3e-11 43.8 1.9 0.051 13.9 0.0 5.0 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY36346.1 - 0.0001 21.1 6.7 0.037 12.7 0.2 3.9 1 1 3 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.12 ORY36346.1 - 0.00018 21.3 1.1 6.7 6.8 0.1 4.4 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 ORY36346.1 - 0.00075 18.6 1.0 2.7 6.9 0.2 4.0 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORY36346.1 - 0.003 16.1 0.0 1.4 7.3 0.0 2.7 1 1 2 3 3 3 3 Cytochrome D1 heme domain DUF1416 PF07210.12 ORY36346.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) Nitr_red_assoc PF09655.10 ORY36347.1 - 0.083 13.5 0.9 0.22 12.2 0.9 1.7 1 0 0 1 1 1 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) DUF572 PF04502.13 ORY36347.1 - 2.3 7.8 22.9 0.18 11.4 11.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) Cwf_Cwc_15 PF04889.12 ORY36347.1 - 4.1 7.1 20.1 0.73 9.5 7.5 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein ICMT PF04140.14 ORY36349.1 - 2.1e-21 76.1 0.9 3.5e-21 75.4 0.9 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 ORY36349.1 - 3.2e-07 30.7 1.0 3.2e-07 30.7 1.0 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 ORY36349.1 - 0.0068 16.0 0.5 0.013 15.1 0.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) zf-rbx1 PF12678.7 ORY36350.1 - 1.2e-10 41.5 1.0 2.8e-10 40.3 1.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 ORY36350.1 - 2.1e-10 40.8 5.7 1e-09 38.6 5.7 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORY36350.1 - 1.8e-07 30.9 0.6 3.3e-07 30.1 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY36350.1 - 2.3e-06 27.3 3.2 2.3e-06 27.3 3.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY36350.1 - 4.2e-05 23.4 1.1 7.8e-05 22.5 1.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY36350.1 - 8.8e-05 22.3 1.4 0.00022 21.0 1.4 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 ORY36350.1 - 0.0001 22.3 1.1 0.00032 20.7 0.4 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 ORY36350.1 - 0.0002 21.4 0.9 0.00036 20.5 0.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 ORY36350.1 - 0.00033 20.4 3.8 0.0012 18.6 0.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 ORY36350.1 - 0.001 18.6 0.5 0.0026 17.4 0.5 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 ORY36350.1 - 0.0019 17.9 1.4 0.03 14.1 0.1 2.4 2 0 0 2 2 2 1 RING-like zinc finger RINGv PF12906.7 ORY36350.1 - 0.069 13.3 0.4 0.16 12.1 0.4 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 ORY36350.1 - 0.18 12.0 2.7 0.34 11.1 2.0 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 ORY36350.1 - 0.45 10.6 1.6 1 9.4 1.6 1.6 1 0 0 1 1 1 0 Zinc-finger Iso_dh PF00180.20 ORY36351.1 - 2.9e-101 339.1 0.0 3.3e-101 338.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase OAM_dimer PF16554.5 ORY36351.1 - 0.042 14.3 0.0 0.16 12.4 0.0 1.9 2 0 0 2 2 2 0 Dimerisation domain of d-ornithine 4,5-aminomutase Phage_30_3 PF08010.11 ORY36351.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 R3H-assoc PF13902.6 ORY36352.1 - 7.3e-05 23.2 1.3 0.00027 21.3 1.3 1.9 1 1 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 ORY36352.1 - 0.023 14.7 0.0 0.062 13.3 0.0 1.7 1 0 0 1 1 1 0 R3H domain Proteasome PF00227.26 ORY36353.1 - 2e-44 151.4 0.0 2.2e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Trans_coact PF16805.5 ORY36353.1 - 0.097 12.8 0.0 2.6 8.2 0.0 2.3 2 0 0 2 2 2 0 Phage late-transcription coactivator BAR PF03114.18 ORY36354.1 - 1.9e-46 158.7 3.4 2.2e-46 158.5 3.4 1.1 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 ORY36354.1 - 4.2e-06 26.6 0.4 7.6e-06 25.8 0.4 1.4 1 1 0 1 1 1 1 BAR domain of APPL family IFT57 PF10498.9 ORY36354.1 - 0.00043 19.4 0.8 0.037 13.0 0.1 2.2 2 0 0 2 2 2 2 Intra-flagellar transport protein 57 DUF4164 PF13747.6 ORY36354.1 - 0.0079 16.4 1.9 0.16 12.3 0.3 2.9 2 2 0 2 2 2 1 Domain of unknown function (DUF4164) SH3BP5 PF05276.14 ORY36354.1 - 0.026 14.3 1.2 0.037 13.8 1.2 1.4 1 0 0 1 1 1 0 SH3 domain-binding protein 5 (SH3BP5) DUF4211 PF13926.6 ORY36354.1 - 0.033 14.2 0.4 4.2 7.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) Arfaptin PF06456.13 ORY36354.1 - 0.06 12.9 2.3 0.13 11.8 2.3 1.7 1 1 0 1 1 1 0 Arfaptin-like domain DUF99 PF01949.16 ORY36354.1 - 0.082 12.3 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF99 DUF948 PF06103.11 ORY36354.1 - 0.12 12.6 1.0 1.4 9.2 0.1 3.1 3 3 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Lipase_3 PF01764.25 ORY36355.1 - 3.6e-06 26.9 0.0 7.5e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 ORY36355.1 - 0.13 11.9 0.0 0.82 9.3 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein Homeobox_KN PF05920.11 ORY36356.1 - 2.1e-16 59.5 0.4 3.9e-16 58.7 0.4 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 ORY36356.1 - 3.3e-06 26.8 0.1 6e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 ORY36356.1 - 0.011 15.2 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez DUF3439 PF11921.8 ORY36356.1 - 0.43 10.5 13.2 0.89 9.5 13.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PhoLip_ATPase_C PF16212.5 ORY36357.1 - 1.6e-76 257.4 18.6 1.6e-76 257.4 18.6 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY36357.1 - 1.9e-24 85.1 3.6 5.4e-24 83.7 3.6 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 ORY36357.1 - 6.7e-13 48.5 0.0 2.2e-12 46.9 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY36357.1 - 1.9e-10 41.4 0.7 0.00021 21.6 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORY36357.1 - 7.1e-08 32.2 0.0 1.7e-07 30.9 0.0 1.6 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 ORY36357.1 - 0.0016 18.2 0.1 0.0046 16.7 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FAD_binding_4 PF01565.23 ORY36358.1 - 1.1e-14 54.3 0.0 1.9e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain zf-C2H2_4 PF13894.6 ORY36359.1 - 2e-08 34.4 3.3 0.007 17.1 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY36359.1 - 2.1e-08 34.2 3.6 0.00071 19.9 0.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY36359.1 - 0.0038 17.6 0.1 0.0038 17.6 0.1 2.7 3 0 0 3 3 3 1 Zinc-finger double domain Cullin PF00888.22 ORY36360.1 - 7.9e-151 503.7 3.0 1e-150 503.3 3.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 ORY36360.1 - 1.9e-23 82.3 0.1 9.9e-23 80.0 0.2 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain Raf1_N PF18578.1 ORY36360.1 - 0.043 14.3 0.3 0.77 10.3 0.1 2.5 2 0 0 2 2 2 0 Rubisco accumulation factor 1 alpha helical domain PCI PF01399.27 ORY36360.1 - 0.39 11.3 6.8 0.64 10.6 0.1 3.2 4 0 0 4 4 4 0 PCI domain SHS2_Rpb7-N PF03876.17 ORY36361.1 - 5.4e-15 55.5 0.0 8.4e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 ORY36361.1 - 2.4e-11 43.8 0.1 8e-11 42.1 0.1 1.8 1 1 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 ORY36361.1 - 0.0027 18.0 0.0 0.0037 17.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 zf-met PF12874.7 ORY36363.1 - 2.8e-06 27.5 1.7 5.5e-06 26.6 1.7 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY36363.1 - 0.00013 22.1 0.8 0.00037 20.7 0.8 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding SNRNP27 PF08648.12 ORY36363.1 - 0.011 15.8 1.0 0.011 15.8 1.0 2.8 3 0 0 3 3 3 0 U4/U6.U5 small nuclear ribonucleoproteins Vfa1 PF08432.10 ORY36363.1 - 0.052 13.9 18.7 0.032 14.5 8.7 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 zf-U1 PF06220.12 ORY36363.1 - 0.41 10.5 5.9 0.29 10.9 1.3 2.3 2 0 0 2 2 2 0 U1 zinc finger DUF719 PF05334.13 ORY36363.1 - 0.66 10.2 10.4 4.6 7.4 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF719) MecA PF05389.12 ORY36363.1 - 1 8.9 10.1 0.33 10.5 2.9 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) RNA_polI_A34 PF08208.11 ORY36363.1 - 3.9 7.5 26.9 1.3 9.1 17.6 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 AAA_11 PF13086.6 ORY36363.1 - 4 7.1 11.2 2 8.1 5.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_pol_Rpc4 PF05132.14 ORY36363.1 - 5.7 7.3 13.5 5.4 7.4 5.6 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 Sacchrp_dh_NADP PF03435.18 ORY36363.1 - 7.3 6.9 6.6 1.8 8.8 0.1 2.7 2 1 1 3 3 3 0 Saccharopine dehydrogenase NADP binding domain CMS1 PF14617.6 ORY36363.1 - 9.9 5.4 16.2 0.5 9.7 4.9 2.2 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Nop52 PF05997.12 ORY36364.1 - 3.1e-60 203.7 0.0 6.5e-60 202.6 0.0 1.5 1 0 0 1 1 1 1 Nucleolar protein,Nop52 Pro_isomerase PF00160.21 ORY36365.1 - 2e-44 151.7 0.0 3.5e-44 150.9 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 ORY36365.1 - 0.0023 18.4 0.2 0.0023 18.4 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4604) eIF3_subunit PF08597.10 ORY36365.1 - 0.003 17.5 13.4 0.12 12.3 1.6 2.2 2 0 0 2 2 2 2 Translation initiation factor eIF3 subunit Nup54 PF13874.6 ORY36365.1 - 0.0048 17.0 1.1 0.0052 16.9 0.0 1.5 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 DUF4119 PF13494.6 ORY36365.1 - 0.11 12.7 2.0 4.6 7.4 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) TAF8_C PF10406.9 ORY36365.1 - 1.8 9.2 7.6 0.16 12.5 0.9 2.3 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term Transglut_core PF01841.19 ORY36366.1 - 1.1e-06 29.1 0.0 4.5e-06 27.1 0.0 2.2 1 1 0 1 1 1 1 Transglutaminase-like superfamily IMS PF00817.20 ORY36367.1 - 1.2e-34 119.5 0.1 2.6e-34 118.4 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 ORY36367.1 - 2.7e-15 57.1 0.0 6.1e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain REV1_C PF16727.5 ORY36367.1 - 6.4e-08 32.9 0.3 1.4e-07 31.8 0.3 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain BRCT_2 PF16589.5 ORY36367.1 - 5e-05 23.6 0.0 0.00012 22.4 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_HHH PF11798.8 ORY36367.1 - 0.0036 17.5 0.0 0.0096 16.2 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif LIG3_BRCT PF16759.5 ORY36367.1 - 0.047 14.0 0.2 0.1 12.9 0.2 1.5 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain Ribosom_S12_S23 PF00164.25 ORY36368.1 - 3.5e-34 116.8 2.2 4.5e-34 116.5 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S12 PF17487.2 ORY36368.1 - 0.033 14.9 0.0 0.26 12.0 0.0 2.2 2 1 0 2 2 2 0 Ribosomal protein S12 Amino_oxidase PF01593.24 ORY36370.1 - 3.7e-18 66.0 0.3 3.5e-17 62.9 0.3 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY36370.1 - 1.2e-13 51.0 0.1 5.2e-13 49.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY36370.1 - 1.2e-06 28.4 3.3 1.5e-05 24.7 0.0 2.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY36370.1 - 0.00035 19.9 0.1 0.03 13.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY36370.1 - 0.00097 18.3 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 ORY36370.1 - 0.007 16.4 3.2 1.5 8.8 0.0 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding Thi4 PF01946.17 ORY36370.1 - 0.011 15.0 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.6 ORY36370.1 - 0.061 12.5 0.2 0.3 10.2 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF1365 PF07103.11 ORY36371.1 - 2.2e-55 188.0 0.2 4e-55 187.1 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) CMAS PF02353.20 ORY36372.1 - 1.6e-75 253.9 0.1 2.2e-75 253.5 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 ORY36372.1 - 4.5e-11 43.3 0.0 1.3e-10 41.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY36372.1 - 2.1e-10 41.1 0.0 4.9e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY36372.1 - 2.2e-08 34.1 0.0 9.6e-08 32.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY36372.1 - 3.4e-08 33.4 0.0 6.5e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY36372.1 - 2.9e-06 27.9 0.0 6.3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY36372.1 - 3.3e-05 23.5 0.0 5.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 ORY36372.1 - 0.0013 18.5 0.0 0.003 17.3 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 ORY36372.1 - 0.0023 17.4 0.0 0.0044 16.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.17 ORY36372.1 - 0.0034 16.6 0.0 0.0066 15.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase RrnaAD PF00398.20 ORY36372.1 - 0.028 13.5 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.7 ORY36372.1 - 0.036 14.0 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Spermine_synth PF01564.17 ORY36372.1 - 0.061 12.7 0.1 0.22 10.9 0.1 1.8 1 1 1 2 2 2 0 Spermine/spermidine synthase domain CMAS PF02353.20 ORY36373.1 - 1.9e-75 253.7 0.2 2.6e-75 253.3 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 ORY36373.1 - 5.3e-11 43.1 0.0 1.3e-10 41.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY36373.1 - 2.2e-10 41.0 0.0 4.9e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY36373.1 - 2.8e-08 33.8 0.0 9.6e-08 32.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY36373.1 - 3.9e-08 33.2 0.0 6.5e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY36373.1 - 3.4e-06 27.7 0.0 6.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY36373.1 - 3.3e-05 23.5 0.0 5.9e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 ORY36373.1 - 0.0012 18.6 0.0 0.0029 17.4 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 ORY36373.1 - 0.0026 17.2 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.17 ORY36373.1 - 0.0036 16.5 0.0 0.0066 15.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase RrnaAD PF00398.20 ORY36373.1 - 0.028 13.5 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.7 ORY36373.1 - 0.041 13.8 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Spermine_synth PF01564.17 ORY36373.1 - 0.063 12.7 0.1 0.22 10.9 0.1 1.7 1 1 1 2 2 2 0 Spermine/spermidine synthase domain FmiP_Thoc5 PF09766.9 ORY36374.1 - 8.9e-42 143.7 30.0 2.2e-36 125.9 5.9 3.2 3 0 0 3 3 3 2 Fms-interacting protein/Thoc5 TFIIA PF03153.13 ORY36374.1 - 0.00099 19.2 27.1 0.00099 19.2 27.1 2.4 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Rhodanese PF00581.20 ORY36375.1 - 2.3e-25 89.2 0.0 7.2e-12 45.8 0.0 2.3 2 0 0 2 2 2 2 Rhodanese-like domain GET2 PF08690.10 ORY36376.1 - 0.0057 16.4 4.4 0.061 13.0 4.4 2.4 1 1 0 1 1 1 1 GET complex subunit GET2 LRR_8 PF13855.6 ORY36377.1 - 1.3e-09 37.7 4.1 7e-07 28.9 1.3 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY36377.1 - 7e-08 32.7 6.9 0.00083 19.7 0.2 2.9 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY36377.1 - 0.00026 21.1 0.2 1.5 9.6 0.1 3.9 3 0 0 3 3 3 2 Leucine Rich Repeat PAN_4 PF14295.6 ORY36377.1 - 0.0017 18.2 29.2 0.03 14.2 4.1 5.0 5 0 0 5 5 5 3 PAN domain PAN_3 PF08277.12 ORY36377.1 - 0.0069 16.2 1.6 0.0069 16.2 1.6 4.7 5 0 0 5 5 5 2 PAN-like domain LRR_6 PF13516.6 ORY36377.1 - 0.077 13.1 2.4 28 5.1 0.1 3.7 3 0 0 3 3 3 0 Leucine Rich repeat PSS PF03034.15 ORY36378.1 - 2.7e-114 381.6 10.9 2.7e-114 381.6 10.9 1.4 2 0 0 2 2 2 1 Phosphatidyl serine synthase DUF726 PF05277.12 ORY36381.1 - 7.5e-99 330.9 7.1 2.4e-76 256.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF726) Phage_antitermQ PF06530.12 ORY36381.1 - 0.048 13.6 0.1 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 Phage antitermination protein Q CDK2AP PF09806.9 ORY36381.1 - 4.3 7.3 7.5 1.2 9.1 2.4 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Ribosom_S12_S23 PF00164.25 ORY36382.1 - 1.1e-50 170.0 0.4 1.4e-50 169.7 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 WD40 PF00400.32 ORY36383.1 - 1.4e-69 228.3 23.2 8.5e-11 42.2 0.2 9.2 9 0 0 9 9 9 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY36383.1 - 3.1e-24 85.1 3.0 0.00032 21.0 0.1 6.1 2 2 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY36383.1 - 4.1e-09 35.6 3.7 0.1 11.2 0.2 5.6 3 3 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORY36383.1 - 2.8e-08 33.1 1.6 0.0094 14.9 0.0 4.3 2 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ORY36383.1 - 1e-05 25.0 0.0 0.71 9.2 0.0 3.3 3 0 0 3 3 3 2 WD40-like domain Nbas_N PF15492.6 ORY36383.1 - 2.4e-05 23.8 0.4 0.039 13.3 0.0 3.4 2 2 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 ORY36383.1 - 0.00019 20.1 0.1 0.048 12.2 0.0 3.3 3 1 0 3 3 3 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 ORY36383.1 - 0.00024 20.0 0.6 0.37 9.5 0.0 3.4 2 1 0 3 3 3 1 Nup133 N terminal like FAD_binding_9 PF08021.11 ORY36383.1 - 0.0055 16.9 0.0 0.2 11.9 0.0 2.5 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain Ret2_MD PF18528.1 ORY36383.1 - 0.0062 16.9 0.0 4.6 7.7 0.0 3.4 4 0 0 4 4 4 1 RNA editing 3' terminal uridylyl transferase 2 middle domain PD40 PF07676.12 ORY36383.1 - 0.0063 16.4 2.8 4.7 7.3 0.0 3.9 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Frtz PF11768.8 ORY36383.1 - 0.083 11.2 0.0 0.23 9.7 0.0 1.8 2 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Ribosomal_S14 PF00253.21 ORY36384.1 - 8.5e-17 60.7 1.6 9.3e-17 60.5 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Mito_carr PF00153.27 ORY36385.1 - 5.5e-49 164.1 10.3 1.2e-16 60.4 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 ORY36386.1 - 5.4e-52 173.7 11.1 2e-17 62.9 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein MtrH PF02007.18 ORY36386.1 - 0.059 12.5 0.1 0.091 11.8 0.1 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit Bromodomain PF00439.25 ORY36387.1 - 3.2e-18 65.6 0.3 7.2e-18 64.4 0.3 1.6 1 0 0 1 1 1 1 Bromodomain Ank_2 PF12796.7 ORY36387.1 - 4.4e-12 46.4 0.1 5.8e-06 26.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY36387.1 - 2.3e-10 40.5 0.6 2.4e-08 34.1 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY36387.1 - 2.3e-05 24.8 0.1 0.014 16.0 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY36387.1 - 0.00023 21.3 0.0 0.13 12.9 0.0 4.0 4 0 0 4 4 4 1 Ankyrin repeat Ank PF00023.30 ORY36387.1 - 0.005 17.2 0.0 2.1 9.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat APG5 PF04106.12 ORY36387.1 - 0.24 11.0 2.3 0.93 9.0 0.0 2.8 2 2 0 2 2 2 0 Autophagy protein Apg5 Lipase_3 PF01764.25 ORY36388.1 - 1e-13 51.4 0.0 1.6e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 ORY36388.1 - 0.017 14.8 0.1 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 ORY36388.1 - 0.1 13.2 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 ORY36388.1 - 0.19 11.3 0.8 3.9 6.9 0.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2974) Amino_oxidase PF01593.24 ORY36390.1 - 0.12 11.6 0.0 0.12 11.6 0.0 2.3 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase Spherulin4 PF12138.8 ORY36390.1 - 0.19 11.3 4.0 0.63 9.6 3.9 2.1 1 1 0 1 1 1 0 Spherulation-specific family 4 Ubie_methyltran PF01209.18 ORY36391.1 - 3.1e-80 268.9 0.1 3.6e-80 268.7 0.1 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 ORY36391.1 - 2.8e-16 60.0 0.0 5.6e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY36391.1 - 2.2e-15 57.1 0.0 5.1e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY36391.1 - 2.6e-12 46.8 0.0 4.2e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY36391.1 - 6.6e-10 39.6 0.0 1.3e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY36391.1 - 2.1e-05 24.4 0.0 3.4e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.19 ORY36391.1 - 0.00095 18.8 0.0 0.031 13.8 0.0 2.1 1 1 1 2 2 2 1 MraW methylase family MTS PF05175.14 ORY36391.1 - 0.0031 17.1 0.0 0.0078 15.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 ORY36391.1 - 0.027 14.4 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.26 ORY36391.1 - 0.032 14.2 0.1 0.086 12.8 0.1 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_8 PF05148.15 ORY36391.1 - 0.095 12.5 0.0 0.29 10.9 0.0 1.9 3 0 0 3 3 3 0 Hypothetical methyltransferase ABC_membrane_2 PF06472.15 ORY36423.1 - 2.9e-73 246.6 0.1 4.1e-73 246.1 0.1 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 ORY36423.1 - 5.3e-18 65.9 0.0 9.7e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY36423.1 - 3.7e-05 23.7 0.0 6.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY36423.1 - 0.00018 21.0 0.1 0.034 13.6 0.1 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORY36423.1 - 0.00027 21.5 0.2 0.00076 20.0 0.0 1.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 ORY36423.1 - 0.0051 16.5 0.1 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_27 PF13514.6 ORY36423.1 - 0.025 14.2 0.1 0.14 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 ORY36423.1 - 0.026 13.4 0.0 0.041 12.7 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein RsgA_GTPase PF03193.16 ORY36423.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_15 PF13175.6 ORY36423.1 - 0.42 10.3 1.3 0.51 10.0 0.2 1.6 2 0 0 2 2 2 0 AAA ATPase domain AIM24 PF01987.17 ORY36425.1 - 2.3e-22 79.8 0.0 3.1e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 RGS PF00615.19 ORY36426.1 - 4.7e-11 43.0 0.0 1.6e-10 41.2 0.0 1.8 1 1 0 1 1 1 1 Regulator of G protein signaling domain RGS PF00615.19 ORY36427.1 - 5.5e-13 49.2 0.2 1.4e-12 48.0 0.2 1.5 1 1 0 1 1 1 1 Regulator of G protein signaling domain RGS PF00615.19 ORY36428.1 - 6.2e-09 36.1 0.0 7.7e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS PF00615.19 ORY36429.1 - 1.6e-48 163.8 0.5 6.1e-14 52.3 0.1 4.2 4 0 0 4 4 4 4 Regulator of G protein signaling domain RGS PF00615.19 ORY36430.1 - 9.4e-14 51.7 1.1 1.4e-13 51.2 1.1 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain Beta_lactamase3 PF17030.5 ORY36430.1 - 0.085 12.1 0.6 0.12 11.5 0.6 1.3 1 1 0 1 1 1 0 Putative beta-lactamase-like family RGS PF00615.19 ORY36431.1 - 3.9e-05 23.9 0.1 5.8e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain DNA_pol_A_exo1 PF01612.20 ORY36432.1 - 0.00042 20.1 0.0 0.00068 19.4 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease DUF4946 PF16304.5 ORY36433.1 - 0.00028 20.6 0.1 0.042 13.6 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4946) TTC5_OB PF16669.5 ORY36434.1 - 4e-13 49.1 0.1 7.7e-13 48.1 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat protein 5 OB fold domain TPR_17 PF13431.6 ORY36434.1 - 4e-09 36.2 0.1 0.012 15.9 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY36434.1 - 0.00066 19.4 8.9 0.36 10.7 0.1 5.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TOM20_plant PF06552.12 ORY36434.1 - 0.0029 17.4 0.0 2.8 7.7 0.0 2.4 1 1 1 2 2 2 2 Plant specific mitochondrial import receptor subunit TOM20 TPR_11 PF13414.6 ORY36434.1 - 0.0087 15.7 0.0 9 6.1 0.0 3.5 4 0 0 4 4 4 2 TPR repeat TPR_8 PF13181.6 ORY36434.1 - 0.079 13.2 7.0 8.5 6.9 0.1 5.5 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY36434.1 - 0.48 10.7 15.0 14 6.1 0.0 6.3 8 0 0 8 8 8 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.25 ORY36437.1 - 3.8e-14 52.9 0.0 4.7e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY36437.1 - 4.6e-10 39.8 0.0 7e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY36437.1 - 7.5e-06 25.9 0.0 1.2e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORY36437.1 - 0.00017 22.3 0.0 0.00021 22.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY36437.1 - 0.0045 16.9 0.0 0.0098 15.8 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 ORY36437.1 - 0.16 11.6 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SGP PF17228.2 ORY36441.1 - 0.00036 21.3 11.9 0.00085 20.1 11.9 1.6 1 0 0 1 1 1 1 Sulphur globule protein SGP PF17228.2 ORY36442.1 - 0.16 12.8 2.7 0.45 11.4 2.7 1.7 1 0 0 1 1 1 0 Sulphur globule protein BPS1 PF05633.11 ORY36444.1 - 0.3 10.0 1.9 0.42 9.6 1.9 1.1 1 0 0 1 1 1 0 Protein BYPASS1-related DUF4394 PF14339.6 ORY36446.1 - 0.12 11.7 0.0 8.2 5.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4394) Acetyltransf_1 PF00583.25 ORY36449.1 - 0.0076 16.5 0.0 0.0094 16.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY36449.1 - 0.025 14.5 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_transf_41 PF13844.6 ORY36449.1 - 0.065 11.7 0.0 0.088 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 41 FR47 PF08445.10 ORY36449.1 - 0.07 13.1 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.7 ORY36449.1 - 0.17 12.5 0.0 0.26 12.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Synaptobrevin PF00957.21 ORY36450.1 - 0.073 12.9 4.4 0.079 12.8 0.3 2.9 2 0 0 2 2 2 0 Synaptobrevin Pox_MCEL PF03291.16 ORY36451.1 - 7.1e-74 248.9 0.0 1.5e-73 247.8 0.0 1.4 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 ORY36451.1 - 3.3e-14 53.3 0.0 6.7e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY36451.1 - 1.5e-10 41.6 0.0 2.8e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY36451.1 - 1e-09 38.4 0.0 1.5e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY36451.1 - 3.8e-09 37.2 0.0 6.6e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 ORY36451.1 - 4.1e-07 29.4 0.0 1e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_23 PF13489.6 ORY36451.1 - 8.4e-07 29.0 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY36451.1 - 0.00014 21.3 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 ORY36451.1 - 0.0089 16.0 0.1 0.02 14.9 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY36451.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Na_H_Exchanger PF00999.21 ORY36452.1 - 2.8e-56 191.0 44.2 3.4e-56 190.7 44.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Cys_Met_Meta_PP PF01053.20 ORY36453.1 - 3.3e-143 476.8 0.0 3.8e-143 476.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 ORY36453.1 - 3.3e-10 39.5 0.3 5.4e-10 38.8 0.3 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 ORY36453.1 - 5e-10 39.1 0.0 6.8e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ORY36453.1 - 1.1e-09 38.1 0.1 2.2e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 ORY36453.1 - 6.7e-05 22.3 0.0 0.0002 20.7 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 ORY36453.1 - 0.0019 16.9 0.0 0.0028 16.4 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS GDC-P PF02347.16 ORY36453.1 - 0.0075 15.1 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.11 ORY36453.1 - 0.01 14.4 0.1 0.014 13.9 0.1 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase Radical_SAM PF04055.21 ORY36453.1 - 0.11 12.9 0.0 14 6.0 0.0 2.5 3 0 0 3 3 3 0 Radical SAM superfamily Mannosyl_trans3 PF11051.8 ORY36454.1 - 2.7e-25 89.3 0.0 5.6e-24 84.9 0.0 2.1 1 1 0 1 1 1 1 Mannosyltransferase putative Mannosyl_trans3 PF11051.8 ORY36455.1 - 1.4e-26 93.5 0.0 1.4e-23 83.7 0.0 2.9 1 1 1 2 2 2 2 Mannosyltransferase putative UBA_6 PF18039.1 ORY36456.1 - 0.0077 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain PH PF00169.29 ORY36456.1 - 0.05 14.1 0.2 0.53 10.8 0.0 2.2 1 1 1 2 2 2 0 PH domain Mannosyl_trans3 PF11051.8 ORY36458.1 - 8.8e-39 133.5 0.0 4.2e-38 131.3 0.0 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative hnRNP_Q_AcD PF18360.1 ORY36458.1 - 0.034 14.1 0.0 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain Sortilin-Vps10 PF15902.5 ORY36459.1 - 0 1032.1 22.3 5.7e-123 411.0 0.9 4.0 3 1 0 3 3 3 3 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 ORY36459.1 - 4.1e-100 333.2 26.2 8.2e-42 143.4 2.8 3.6 3 0 0 3 3 3 3 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 ORY36459.1 - 3.1e-10 38.5 47.8 3.7 7.9 0.2 14.7 14 0 0 14 14 14 6 BNR/Asp-box repeat PSII_BNR PF14870.6 ORY36459.1 - 1.1e-05 24.8 0.1 0.4 9.9 0.0 4.5 4 0 0 4 4 4 2 Photosynthesis system II assembly factor YCF48 BNR_2 PF13088.6 ORY36459.1 - 0.00046 19.6 4.5 4.7 6.4 0.1 6.0 5 1 0 5 5 5 2 BNR repeat-like domain BNR_6 PF15899.5 ORY36459.1 - 1.9 8.7 6.9 58 4.2 0.1 5.9 6 0 0 6 6 6 0 BNR-Asp box repeat Cytochrom_B561 PF03188.16 ORY36460.1 - 6.8e-12 45.7 7.1 6.8e-12 45.7 7.1 1.9 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 ORY36460.1 - 0.00018 21.6 3.4 0.00035 20.7 1.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF4079) Yip1 PF04893.17 ORY36460.1 - 0.0039 16.9 7.0 0.0045 16.7 5.1 2.0 1 1 1 2 2 2 2 Yip1 domain DUF1129 PF06570.11 ORY36460.1 - 0.0096 15.4 2.4 0.015 14.8 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) Pox_A14 PF05767.12 ORY36460.1 - 0.042 14.0 1.1 0.55 10.4 0.0 2.7 2 2 0 2 2 2 0 Poxvirus virion envelope protein A14 DUF468 PF04318.12 ORY36460.1 - 0.064 14.0 0.8 0.13 13.0 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF468) ETRAMP PF09716.10 ORY36460.1 - 0.1 12.7 0.8 0.97 9.5 0.8 2.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) NADH-u_ox-rdase PF10785.9 ORY36460.1 - 0.12 13.1 0.6 1.2 9.9 0.0 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF4231 PF14015.6 ORY36460.1 - 0.26 11.8 9.8 0.7 10.4 1.7 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF4231) Cytochrom_B561 PF03188.16 ORY36461.1 - 2.6e-15 56.8 6.9 5e-15 55.8 6.9 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4418 PF14387.6 ORY36461.1 - 0.041 14.1 1.2 0.041 14.1 1.2 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4418) DUF4271 PF14093.6 ORY36461.1 - 0.043 13.7 9.3 0.17 11.7 9.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) YwiC PF14256.6 ORY36461.1 - 0.082 13.2 13.9 0.39 11.0 8.2 2.7 1 1 2 3 3 3 0 YwiC-like protein DUF2231 PF09990.9 ORY36461.1 - 0.2 12.1 8.6 0.54 10.7 1.1 2.7 2 1 1 3 3 3 0 Predicted membrane protein (DUF2231) DUF3681 PF12442.8 ORY36461.1 - 0.46 11.0 6.4 0.083 13.4 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3681) DUF4079 PF13301.6 ORY36461.1 - 3.1 8.0 9.8 0.6 10.3 1.7 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4079) Phage_holin_2_4 PF16082.5 ORY36461.1 - 4.4 7.1 5.0 29 4.5 0.2 2.8 1 1 2 3 3 3 0 Bacteriophage holin family, superfamily II-like FAD_binding_2 PF00890.24 ORY36462.1 - 1.7e-74 251.4 0.4 1.7e-74 251.4 0.4 2.0 2 0 0 2 2 2 1 FAD binding domain Cyt-b5 PF00173.28 ORY36462.1 - 9.2e-23 80.2 0.1 3.3e-22 78.4 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 ORY36462.1 - 3.7e-10 39.9 0.9 3.7e-10 39.9 0.9 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY36462.1 - 6.3e-08 32.2 4.6 2.2e-06 27.1 0.3 3.4 2 2 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY36462.1 - 3.8e-07 30.2 0.8 4.3e-06 26.9 0.6 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 ORY36462.1 - 7.2e-07 28.9 0.1 7.2e-07 28.9 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY36462.1 - 5.3e-05 22.1 2.7 0.00066 18.5 0.1 2.9 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 ORY36462.1 - 0.00027 20.1 0.6 0.013 14.6 0.6 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 ORY36462.1 - 0.0029 16.9 0.1 0.0097 15.2 0.1 1.9 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 ORY36462.1 - 0.056 12.7 0.4 0.11 11.8 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain Ribosomal_60s PF00428.19 ORY36462.1 - 0.29 11.8 10.6 0.77 10.4 10.6 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein GAS PF13851.6 ORY36463.1 - 9e-78 260.2 32.0 9e-78 260.2 32.0 3.2 1 1 2 3 3 3 1 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 ORY36463.1 - 3.4 7.0 68.1 3.6 7.0 35.9 3.9 1 1 3 4 4 4 0 Golgin subfamily A member 5 T_hemolysin PF12261.8 ORY36464.1 - 0.0023 17.7 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 Thermostable hemolysin MT-A70 PF05063.14 ORY36465.1 - 4.3e-17 62.6 0.0 7.7e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 MT-A70 Hamartin PF04388.12 ORY36465.1 - 0.91 8.1 15.3 1.1 7.8 15.3 1.0 1 0 0 1 1 1 0 Hamartin protein Thiolase_N PF00108.23 ORY36466.1 - 2.3e-95 318.9 1.7 3.5e-95 318.3 1.7 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY36466.1 - 1.3e-45 154.0 1.9 3.7e-45 152.6 1.9 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ORY36466.1 - 6.1e-06 26.0 5.7 1.5e-05 24.7 2.1 2.7 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 ORY36466.1 - 0.074 12.9 2.9 5.9 6.8 0.2 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Sialidase PF02973.16 ORY36467.1 - 0.032 13.7 0.2 0.048 13.2 0.2 1.2 1 0 0 1 1 1 0 Sialidase, N-terminal domain Flavin_Reduct PF01613.18 ORY36468.1 - 8.2e-09 35.7 0.2 1.8e-07 31.4 0.2 2.0 1 1 0 1 1 1 1 Flavin reductase like domain Sld5 PF05916.11 ORY36470.1 - 5.2e-05 23.7 0.1 9.9e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 GINS complex protein zf-C2H2 PF00096.26 ORY36471.1 - 1.3e-07 31.7 25.3 0.0013 19.1 6.9 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY36471.1 - 4.8e-07 30.1 21.4 0.0022 18.7 6.5 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY36471.1 - 0.00013 22.1 9.2 0.098 13.0 0.6 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY36471.1 - 0.00014 22.1 11.4 0.024 15.0 0.0 4.3 5 0 0 5 5 4 1 Zinc-finger of C2H2 type DUF2321 PF10083.9 ORY36471.1 - 0.0072 16.0 0.1 0.019 14.6 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2321) zf-H2C2_2 PF13465.6 ORY36471.1 - 0.029 14.8 25.4 0.063 13.7 4.1 3.9 4 0 0 4 4 3 0 Zinc-finger double domain Band_3_cyto PF07565.13 ORY36471.1 - 0.4 10.4 7.3 0.074 12.8 3.8 1.6 2 0 0 2 2 2 0 Band 3 cytoplasmic domain GAGA PF09237.11 ORY36471.1 - 0.52 10.2 6.9 0.25 11.2 2.3 2.8 2 1 0 2 2 2 0 GAGA factor IBR PF01485.21 ORY36471.1 - 0.83 9.9 6.5 0.3 11.3 3.5 1.8 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain zf-C2H2_8 PF15909.5 ORY36471.1 - 0.91 9.9 11.2 0.28 11.5 4.1 2.7 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-MYST PF17772.1 ORY36471.1 - 1.6 8.4 7.2 0.8 9.4 0.3 2.8 3 0 0 3 3 3 0 MYST family zinc finger domain zf-C2H2_6 PF13912.6 ORY36471.1 - 2.2 8.4 13.3 6.1 7.0 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger DUF5521 PF17659.1 ORY36471.1 - 8.1 4.1 9.3 13 3.5 9.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5521) zf-C2H2_2 PF12756.7 ORY36471.1 - 9.7 6.6 12.4 1.4 9.3 3.4 3.1 2 1 1 3 3 2 0 C2H2 type zinc-finger (2 copies) DUF5447 PF17525.2 ORY36472.1 - 0.096 13.2 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5447) BPD_transp_1 PF00528.22 ORY36472.1 - 0.29 10.9 14.7 0.035 13.8 1.3 2.2 2 0 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component ESCRT-II PF05871.12 ORY36473.1 - 0.2 11.9 1.6 0.33 11.2 1.0 1.7 2 0 0 2 2 2 0 ESCRT-II complex subunit Fib_alpha PF08702.10 ORY36473.1 - 0.28 11.4 5.8 7.1 6.8 0.0 2.7 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3925 PF13063.6 ORY36476.1 - 0.046 13.9 0.6 0.046 13.9 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3925) Pkinase PF00069.25 ORY36478.1 - 1.7e-65 221.0 0.0 2.8e-65 220.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY36478.1 - 1.2e-38 133.0 0.0 1.9e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY36478.1 - 0.00021 20.2 0.0 0.0026 16.6 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY36478.1 - 0.00027 20.0 0.0 0.00059 18.9 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORY36478.1 - 0.00047 19.6 0.0 0.0054 16.1 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORY36478.1 - 0.0029 17.6 0.0 0.0049 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORY36478.1 - 0.11 12.1 0.0 0.87 9.1 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Abhydrolase_1 PF00561.20 ORY36479.1 - 2.7e-15 56.7 0.1 2.1e-14 53.8 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY36479.1 - 6.4e-10 40.0 0.0 7.6e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY36479.1 - 1.7e-06 27.5 0.0 3.5e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 ORY36479.1 - 0.015 15.0 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein LIDHydrolase PF10230.9 ORY36479.1 - 0.072 12.6 0.0 0.27 10.7 0.0 2.0 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase TRM13 PF05206.14 ORY36479.1 - 0.13 11.7 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 DUF5535 PF17687.1 ORY36479.1 - 0.18 11.9 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5535) Metallophos PF00149.28 ORY36480.1 - 9.1e-08 32.8 0.1 1.7e-07 31.9 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AA_permease PF00324.21 ORY36481.1 - 4.3e-67 226.8 31.8 1.3e-59 202.1 26.0 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 ORY36481.1 - 2.4e-18 66.2 35.7 1.8e-16 60.0 29.8 2.1 1 1 1 2 2 2 2 Amino acid permease adh_short PF00106.25 ORY36482.1 - 7.8e-19 67.9 1.6 1.4e-18 67.1 1.6 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY36482.1 - 5.3e-13 49.1 2.2 8.8e-13 48.4 2.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY36482.1 - 1.8e-05 24.7 0.2 2.7e-05 24.2 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY36482.1 - 0.0051 16.3 0.9 0.042 13.3 0.9 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF4004 PF13171.6 ORY36483.1 - 0.072 13.3 0.2 0.12 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4004) Pkinase PF00069.25 ORY36484.1 - 6.4e-42 143.7 0.1 4.1e-41 141.1 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY36484.1 - 3.6e-17 62.5 0.7 1.8e-16 60.2 0.7 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase CoaE PF01121.20 ORY36486.1 - 1.4e-35 122.6 0.0 2e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase XendoU PF09412.10 ORY36487.1 - 1.7e-37 129.1 1.6 1.6e-19 70.2 1.0 3.3 1 1 1 2 2 2 2 Endoribonuclease XendoU XendoU PF09412.10 ORY36488.1 - 1.2e-69 234.5 1.0 1.4e-45 155.6 0.0 2.4 2 1 1 3 3 3 2 Endoribonuclease XendoU TFIIA PF03153.13 ORY36488.1 - 0.81 9.6 10.8 1 9.3 10.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 ORY36488.1 - 1.6 8.3 13.8 2.6 7.6 13.8 1.4 1 0 0 1 1 1 0 Spt20 family His_Phos_1 PF00300.22 ORY36489.1 - 5.5e-45 153.5 0.0 7.2e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Condensation PF00668.20 ORY36490.1 - 0.097 11.3 0.9 0.47 9.1 0.0 2.1 2 0 0 2 2 2 0 Condensation domain Ecl1 PF12855.7 ORY36490.1 - 7.3 7.7 13.9 17 6.5 13.9 1.5 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins Arf PF00025.21 ORY36491.1 - 1.6e-38 131.9 0.1 2.1e-38 131.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 ORY36491.1 - 1.9e-15 56.8 0.0 3.6e-15 55.9 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 ORY36491.1 - 4.1e-13 49.6 0.0 4.9e-12 46.1 0.0 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 ORY36491.1 - 3.4e-08 33.1 0.0 4.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORY36491.1 - 2.1e-07 30.5 0.0 6.6e-07 28.9 0.0 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 ORY36491.1 - 3.4e-06 26.5 0.5 0.0052 16.0 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 ORY36491.1 - 1.6e-05 25.0 0.1 7e-05 22.9 0.1 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY36491.1 - 0.001 18.6 0.0 0.023 14.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 ORY36491.1 - 0.0077 16.5 0.1 0.3 11.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 ORY36491.1 - 0.012 15.7 0.1 0.58 10.2 0.1 2.2 1 1 1 2 2 2 0 Dynamin family ABC_tran PF00005.27 ORY36491.1 - 0.025 15.1 0.2 0.056 13.9 0.2 1.6 1 1 0 1 1 1 0 ABC transporter VirE PF05272.11 ORY36491.1 - 0.068 12.9 0.0 0.096 12.4 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E FeoB_N PF02421.18 ORY36491.1 - 0.072 12.6 0.3 0.19 11.3 0.1 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 ORY36491.1 - 0.097 13.1 0.1 1.6 9.1 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 ORY36491.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region CRCB PF02537.15 ORY36492.1 - 2.9e-12 46.7 1.1 4.5e-12 46.1 1.1 1.2 1 0 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) GBR2_CC PF18455.1 ORY36492.1 - 0.023 14.8 0.1 0.034 14.3 0.1 1.3 1 0 0 1 1 1 0 Gamma-aminobutyric acid type B receptor subunit 2 coiled-coil domain CRCB PF02537.15 ORY36493.1 - 1.8e-13 50.6 10.1 1.1e-12 48.0 10.1 2.0 1 1 0 1 1 1 1 CrcB-like protein, Camphor Resistance (CrcB) Piwi PF02171.17 ORY36495.1 - 2.2e-76 257.0 0.0 7.2e-76 255.3 0.0 1.7 2 0 0 2 2 2 1 Piwi domain ArgoN PF16486.5 ORY36495.1 - 9.9e-20 71.6 0.2 2.3e-19 70.4 0.2 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 ORY36495.1 - 7.7e-12 45.2 0.3 1.9e-11 43.9 0.0 1.8 2 0 0 2 2 2 1 PAZ domain ArgoL2 PF16488.5 ORY36495.1 - 7.8e-09 35.7 0.1 6.1e-08 32.9 0.0 2.4 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoL1 PF08699.10 ORY36495.1 - 7.9e-09 35.1 0.0 2.5e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 ORY36495.1 - 5.6e-07 29.7 0.0 1.3e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Mid domain of argonaute Piwi PF02171.17 ORY36496.1 - 6.5e-74 248.9 0.0 2.4e-72 243.7 0.0 2.5 2 1 0 2 2 2 1 Piwi domain DNA_primase_lrg PF04104.14 ORY36496.1 - 8.5e-65 218.8 0.0 9.4e-64 215.4 0.0 2.4 1 1 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit ArgoN PF16486.5 ORY36496.1 - 1.8e-19 70.8 0.2 4.4e-19 69.5 0.2 1.8 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 ORY36496.1 - 6.6e-11 42.2 0.0 1.8e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 ORY36496.1 - 1.8e-08 33.9 0.0 4.7e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 ORY36496.1 - 1.8e-07 31.3 0.1 4e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 ORY36496.1 - 1.8e-07 31.4 0.0 1.2e-06 28.7 0.0 2.4 2 0 0 2 2 2 1 Argonaute linker 2 domain Methyltransf_13 PF08421.11 ORY36496.1 - 0.04 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Putative zinc binding domain DUF4200 PF13863.6 ORY36497.1 - 8.9e-33 113.2 25.1 8.9e-33 113.2 25.1 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4200) Phi_1 PF04674.12 ORY36498.1 - 8.7e-21 74.4 8.5 3.4e-20 72.5 8.5 1.9 1 1 0 1 1 1 1 Phosphate-induced protein 1 conserved region Ribosomal_S5 PF00333.20 ORY36499.1 - 1.5e-18 66.6 2.1 8.7e-18 64.1 2.1 2.2 1 1 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 ORY36499.1 - 1.2e-16 59.9 0.1 4e-16 58.2 0.1 1.9 1 1 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 ORY36499.1 - 1.2 9.7 10.4 2.3 8.8 10.4 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 RCC1 PF00415.18 ORY36502.1 - 2.4e-25 88.9 2.4 2.1e-09 37.9 0.1 5.1 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY36502.1 - 7.8e-14 51.0 16.8 2.1e-06 27.4 0.4 5.0 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat Mito_carr PF00153.27 ORY36503.1 - 2.4e-53 178.0 5.6 6.1e-20 70.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 ORY36503.1 - 0.00032 20.9 0.5 1.6 9.0 0.0 3.4 2 1 0 3 3 3 2 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase 60KD_IMP PF02096.20 ORY36503.1 - 0.0013 18.7 0.8 0.012 15.5 0.0 2.5 2 1 1 3 3 3 1 60Kd inner membrane protein DUF2700 PF10912.8 ORY36503.1 - 0.036 14.1 0.5 16 5.5 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2700) MtrF PF09472.10 ORY36503.1 - 0.075 12.4 0.6 0.43 10.0 0.0 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) PrcB_C PF14343.6 ORY36503.1 - 0.092 12.9 1.3 1.9 8.7 0.1 2.4 2 0 0 2 2 2 0 PrcB C-terminal Ank_2 PF12796.7 ORY36504.1 - 1.5e-23 83.2 2.0 1.3e-09 38.5 0.0 3.8 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY36504.1 - 2.6e-13 49.9 2.3 1.5 9.2 0.1 7.2 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY36504.1 - 7.3e-12 45.6 6.9 0.00012 22.6 0.0 5.1 2 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.30 ORY36504.1 - 1.5e-09 37.9 4.0 1.8 9.2 0.1 7.1 3 1 4 7 7 7 3 Ankyrin repeat Ank_3 PF13606.6 ORY36504.1 - 2e-08 33.8 0.1 12 6.8 0.0 6.6 7 0 0 7 7 7 2 Ankyrin repeat AP_endonuc_2 PF01261.24 ORY36505.1 - 5.4e-36 124.0 0.1 7.5e-36 123.5 0.1 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Ndc1_Nup PF09531.10 ORY36505.1 - 2.5 6.7 9.2 2.9 6.4 9.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CCSAP PF15748.5 ORY36505.1 - 4.4 7.4 19.8 6.8 6.8 19.8 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated TPR_10 PF13374.6 ORY36506.1 - 1.2e-45 152.1 0.2 4.6e-07 29.5 0.0 7.3 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 ORY36506.1 - 2.6e-43 146.2 1.5 2.4e-14 53.4 0.0 5.1 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_1 PF00515.28 ORY36506.1 - 1.3e-12 47.0 8.0 0.0088 15.8 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 ORY36506.1 - 1.4e-12 46.6 1.8 0.086 12.9 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY36506.1 - 1.3e-11 43.6 8.2 0.0025 17.8 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY36506.1 - 2.7e-08 33.4 13.3 0.39 11.0 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY36506.1 - 4.7e-08 33.4 0.0 0.0026 18.2 0.0 4.3 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY36506.1 - 2.2e-06 27.3 0.3 0.00081 18.9 0.8 2.1 1 1 1 2 2 2 2 MalT-like TPR region TPR_16 PF13432.6 ORY36506.1 - 2e-05 25.2 0.1 44 4.8 0.1 6.5 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY36506.1 - 3e-05 24.5 0.4 24 6.1 0.0 5.5 5 1 1 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY36506.1 - 0.0024 18.1 6.3 11 6.3 0.0 4.9 2 2 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 ORY36506.1 - 0.0073 16.6 0.2 18 5.7 0.0 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORY36506.1 - 0.02 15.2 0.7 18 6.0 0.0 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF952 PF06108.12 ORY36508.1 - 8.4e-17 61.0 0.0 1e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) MSC PF09402.10 ORY36511.1 - 2.8e-15 56.6 0.9 5.2e-15 55.7 0.9 1.4 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 ORY36511.1 - 1.6e-05 24.5 0.0 2.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 HeH/LEM domain HeH PF12949.7 ORY36512.1 - 7.1e-07 28.8 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 HeH/LEM domain CAP_N PF01213.19 ORY36512.1 - 1.9 7.9 8.3 0.47 9.9 2.7 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Pkinase PF00069.25 ORY36513.1 - 4.3e-57 193.5 0.0 5.8e-57 193.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY36513.1 - 3.6e-27 95.3 0.0 5e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY36513.1 - 8.1e-05 21.6 0.0 0.00016 20.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORY36513.1 - 0.0017 17.7 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORY36513.1 - 0.0022 17.6 0.1 0.0082 15.8 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 ORY36513.1 - 0.0055 16.7 0.0 0.59 10.0 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 ORY36513.1 - 0.007 16.0 0.5 0.21 11.2 0.1 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 ORY36513.1 - 0.083 12.2 0.1 0.18 11.1 0.0 1.5 2 0 0 2 2 2 0 Kinase-like rRNA_proc-arch PF13234.6 ORY36514.1 - 1.2e-75 254.9 0.3 2.1e-75 254.1 0.3 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 ORY36514.1 - 1.6e-52 177.5 0.7 3.5e-52 176.4 0.7 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 ORY36514.1 - 4.4e-19 68.9 0.0 1.6e-18 67.1 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY36514.1 - 4e-07 30.4 0.0 2.1e-06 28.1 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY36514.1 - 2.2e-05 24.5 0.0 6.4e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY36514.1 - 0.0005 20.3 0.0 0.018 15.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 ORY36514.1 - 0.0099 15.0 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein BRE1 PF08647.11 ORY36514.1 - 0.024 14.7 0.5 0.024 14.7 0.5 2.7 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF3886 PF13025.6 ORY36514.1 - 0.058 13.6 0.7 0.19 11.9 0.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) NCD2 PF04905.13 ORY36514.1 - 2.3 8.2 4.5 22 5.0 0.1 3.2 3 0 0 3 3 3 0 NAB conserved region 2 (NCD2) Prot_ATP_ID_OB PF16450.5 ORY36515.1 - 4.2 7.4 6.7 2.1 8.3 0.2 3.1 1 1 1 2 2 2 0 Proteasomal ATPase OB C-terminal domain IL4Ra_N PF09238.10 ORY36516.1 - 0.018 15.4 2.0 0.028 14.7 0.4 2.2 2 1 0 2 2 2 0 Interleukin-4 receptor alpha chain, N-terminal Mucin PF01456.17 ORY36518.1 - 0.075 13.0 20.1 0.18 11.8 20.1 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Oxidored_FMN PF00724.20 ORY36519.1 - 4.3e-86 289.3 0.0 5.5e-86 288.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 ORY36519.1 - 0.028 13.9 0.1 6.5 6.1 0.0 2.6 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel THF_DHG_CYH PF00763.23 ORY36520.1 - 4.1e-23 81.9 0.0 8.6e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 ORY36520.1 - 1.6e-15 56.8 0.3 2.6e-09 36.6 0.0 2.6 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DpaA_N PF16924.5 ORY36520.1 - 0.086 12.9 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain Galactosyl_T PF01762.21 ORY36521.1 - 8.6e-12 45.3 0.0 7.2e-05 22.7 0.0 2.5 1 1 1 2 2 2 2 Galactosyltransferase Pyr_redox_2 PF07992.14 ORY36522.1 - 4.2e-42 144.4 0.3 6.5e-42 143.8 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORY36522.1 - 9.2e-24 83.8 0.5 2.5e-23 82.4 0.5 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ORY36522.1 - 1.6e-10 41.4 2.6 2.6e-10 40.7 0.1 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY36522.1 - 0.016 14.4 0.0 3.6 6.7 0.0 2.4 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 ORY36522.1 - 0.068 12.2 0.6 0.99 8.4 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Oxidored_FMN PF00724.20 ORY36523.1 - 8.4e-92 308.0 0.0 9.6e-92 307.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Phage-tail_3 PF13550.6 ORY36524.1 - 0.021 14.7 0.0 0.029 14.2 0.0 1.2 1 0 0 1 1 1 0 Putative phage tail protein Lipocalin_4 PF13648.6 ORY36525.1 - 6.5 7.8 7.8 77 4.4 6.0 3.3 1 1 1 2 2 2 0 Lipocalin-like domain Clr2_transil PF16761.5 ORY36526.1 - 1.1e-09 39.0 0.1 3.5e-09 37.4 0.1 1.9 1 1 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 zf-C2H2 PF00096.26 ORY36526.1 - 2.7e-05 24.3 14.6 0.012 16.1 0.1 4.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY36526.1 - 0.00013 22.5 13.4 0.38 11.7 0.1 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY36526.1 - 0.0077 16.5 7.3 1.9 8.8 1.0 4.1 3 1 1 4 4 4 2 C2H2-type zinc ribbon zf_Hakai PF18408.1 ORY36526.1 - 0.0088 15.7 0.2 0.55 10.0 0.1 2.5 2 0 0 2 2 2 1 C2H2 Hakai zinc finger domain zf-C2H2_6 PF13912.6 ORY36526.1 - 0.17 11.9 0.5 7.3 6.7 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger FAR1 PF03101.15 ORY36526.1 - 0.74 10.6 3.9 0.84 10.4 0.3 2.5 2 0 0 2 2 2 0 FAR1 DNA-binding domain BTB PF00651.31 ORY36527.1 - 1.2e-12 48.1 0.0 2.2e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Acyl_transf_3 PF01757.22 ORY36528.1 - 1.5e-11 44.0 36.2 3.8e-10 39.4 36.2 2.8 1 1 0 1 1 1 1 Acyltransferase family DUF1295 PF06966.12 ORY36529.1 - 4.8e-35 121.2 0.3 5.3e-35 121.0 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 ORY36529.1 - 9.1e-05 22.5 0.8 0.00011 22.2 0.8 1.3 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 ORY36529.1 - 0.0017 18.8 0.1 0.003 17.9 0.1 1.5 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family peroxidase PF00141.23 ORY36530.1 - 1.5e-21 77.2 0.4 2.9e-21 76.2 0.4 1.5 1 0 0 1 1 1 1 Peroxidase Band_7 PF01145.25 ORY36531.1 - 8.1e-24 84.6 1.3 1.2e-23 84.1 1.3 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 ORY36531.1 - 0.015 15.0 0.3 0.027 14.2 0.2 1.4 1 1 0 1 1 1 0 SPFH domain-Band 7 family LRS4 PF10422.9 ORY36531.1 - 0.029 14.0 0.6 0.029 14.0 0.6 1.4 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 Band_7 PF01145.25 ORY36532.1 - 3e-29 102.3 0.2 4.3e-29 101.8 0.2 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 ORY36532.1 - 0.014 15.1 0.1 0.021 14.6 0.1 1.2 1 0 0 1 1 1 0 SPFH domain-Band 7 family Band_7 PF01145.25 ORY36533.1 - 1.1e-06 28.8 1.5 0.0043 17.1 0.2 2.1 1 1 1 2 2 2 2 SPFH domain / Band 7 family DUF2605 PF10792.9 ORY36533.1 - 0.061 13.3 1.2 1.1 9.3 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2605) LRS4 PF10422.9 ORY36533.1 - 0.1 12.1 0.5 0.12 11.9 0.5 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 WEMBL PF05701.11 ORY36535.1 - 0.0022 16.8 7.1 0.0032 16.2 7.1 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light SlyX PF04102.12 ORY36535.1 - 0.0037 17.9 7.2 0.023 15.3 0.3 3.7 2 1 1 3 3 3 1 SlyX Snapin_Pallidin PF14712.6 ORY36535.1 - 0.0055 17.1 7.6 0.021 15.3 2.4 2.9 2 1 0 2 2 2 1 Snapin/Pallidin Tropomyosin_1 PF12718.7 ORY36535.1 - 0.0057 16.8 7.9 0.0057 16.8 7.9 2.3 2 1 0 2 2 1 1 Tropomyosin like MoeA_N PF03453.17 ORY36535.1 - 0.0085 15.9 0.1 0.017 14.9 0.1 1.6 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) Jnk-SapK_ap_N PF09744.9 ORY36535.1 - 0.0088 16.3 5.8 0.044 14.0 5.8 2.2 1 1 0 1 1 1 1 JNK_SAPK-associated protein-1 Macoilin PF09726.9 ORY36535.1 - 0.009 14.6 6.8 0.014 14.0 6.8 1.3 1 0 0 1 1 1 1 Macoilin family HMMR_N PF15905.5 ORY36535.1 - 0.0092 15.5 8.9 0.14 11.6 3.2 2.4 2 0 0 2 2 2 2 Hyaluronan mediated motility receptor N-terminal CCDC144C PF14915.6 ORY36535.1 - 0.0099 15.0 8.9 0.24 10.5 0.2 2.5 2 0 0 2 2 2 2 CCDC144C protein coiled-coil region Tropomyosin PF00261.20 ORY36535.1 - 0.012 15.0 13.6 0.081 12.3 3.8 2.8 3 0 0 3 3 3 0 Tropomyosin AKNA PF12443.8 ORY36535.1 - 0.058 14.1 1.4 10 6.8 0.2 3.0 1 1 1 2 2 2 0 AT-hook-containing transcription factor MscS_porin PF12795.7 ORY36535.1 - 0.072 12.6 9.4 0.43 10.1 1.9 2.7 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain IFT57 PF10498.9 ORY36535.1 - 0.084 11.8 10.3 0.31 10.0 8.1 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Sec34 PF04136.15 ORY36535.1 - 0.087 12.7 6.6 0.099 12.5 3.0 2.3 2 0 0 2 2 2 0 Sec34-like family EzrA PF06160.12 ORY36535.1 - 0.1 10.7 7.3 0.11 10.6 2.1 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA STAT_alpha PF01017.20 ORY36535.1 - 0.11 12.4 5.3 0.062 13.2 2.0 2.0 1 1 1 2 2 2 0 STAT protein, all-alpha domain Spc7 PF08317.11 ORY36535.1 - 0.12 11.3 13.7 1 8.2 6.2 2.2 1 1 0 2 2 2 0 Spc7 kinetochore protein MCC-bdg_PDZ PF10506.9 ORY36535.1 - 0.27 11.3 3.2 3.5 7.7 0.2 3.2 4 0 0 4 4 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Golgin_A5 PF09787.9 ORY36535.1 - 0.29 10.6 11.6 0.039 13.4 2.6 2.4 1 1 2 3 3 3 0 Golgin subfamily A member 5 SKA2 PF16740.5 ORY36535.1 - 0.31 10.9 6.0 5.3 6.9 4.6 3.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Uds1 PF15456.6 ORY36535.1 - 0.52 10.5 8.3 4.5 7.5 8.0 2.9 1 1 0 1 1 1 0 Up-regulated During Septation Laminin_II PF06009.12 ORY36535.1 - 0.55 10.3 12.3 0.71 9.9 4.0 2.9 2 1 0 3 3 3 0 Laminin Domain II TMPIT PF07851.13 ORY36535.1 - 0.65 9.2 4.4 0.95 8.6 3.4 1.5 1 1 0 1 1 1 0 TMPIT-like protein ATG16 PF08614.11 ORY36535.1 - 0.66 10.2 14.0 13 6.0 11.6 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) NBP1 PF08537.10 ORY36535.1 - 0.7 9.3 11.0 0.045 13.2 5.0 1.9 2 1 0 2 2 2 0 Fungal Nap binding protein NBP1 CLZ PF16526.5 ORY36535.1 - 0.71 10.3 4.8 22 5.5 0.0 3.3 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Fez1 PF06818.15 ORY36535.1 - 0.71 10.3 11.9 0.46 10.9 9.6 1.8 1 1 1 2 2 2 0 Fez1 DUF948 PF06103.11 ORY36535.1 - 0.77 10.1 5.9 7.9 6.8 0.2 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF16 PF01519.16 ORY36535.1 - 1.1 9.8 7.3 45 4.6 7.3 2.7 1 1 0 1 1 1 0 Protein of unknown function DUF16 Nup54 PF13874.6 ORY36535.1 - 1.2 9.3 9.9 0.69 10.0 5.0 2.3 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 FliJ PF02050.16 ORY36535.1 - 1.5 9.0 13.5 1.2 9.4 1.7 2.8 3 0 0 3 3 2 0 Flagellar FliJ protein DUF724 PF05266.14 ORY36535.1 - 1.9 8.3 6.8 7.7 6.3 6.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF724) KELK PF15796.5 ORY36535.1 - 2.2 8.8 11.5 19 5.8 4.1 3.5 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF4201 PF13870.6 ORY36535.1 - 2.3 7.9 11.3 0.74 9.5 4.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) NPV_P10 PF05531.12 ORY36535.1 - 3 8.4 9.8 2.3e+03 -0.9 9.8 3.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein GIT_CC PF16559.5 ORY36535.1 - 3.8 7.5 6.3 55 3.7 0.1 3.5 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor V_ATPase_I PF01496.19 ORY36535.1 - 3.8 5.3 6.8 1 7.2 3.0 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family XhlA PF10779.9 ORY36535.1 - 5.4 7.3 10.6 16 5.7 1.5 3.5 2 1 1 3 3 3 0 Haemolysin XhlA Occludin_ELL PF07303.13 ORY36535.1 - 6.1 7.6 8.5 10 6.9 3.3 2.7 2 0 0 2 2 2 0 Occludin homology domain Csm1_N PF18504.1 ORY36535.1 - 8 6.9 9.7 10 6.5 0.2 4.1 3 1 0 3 3 3 0 Csm1 N-terminal domain DUF1664 PF07889.12 ORY36535.1 - 8 6.5 7.6 36 4.4 1.9 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) BST2 PF16716.5 ORY36535.1 - 9.1 6.9 11.1 45 4.7 0.4 3.2 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 RA PF00788.23 ORY36539.1 - 1.2e-15 57.9 0.0 2e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 ORY36539.1 - 2.5e-06 27.0 0.0 4.5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 ORY36539.1 - 0.052 13.8 0.2 0.1 12.9 0.2 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain DUF572 PF04502.13 ORY36539.1 - 0.61 9.7 3.9 0.2 11.2 1.0 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF572) DUF3597 PF12200.8 ORY36539.1 - 0.71 10.4 2.9 0.58 10.7 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) AAA PF00004.29 ORY36540.1 - 7.2e-18 65.3 0.0 1.2e-17 64.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 ORY36540.1 - 9.1e-17 61.2 0.0 3.3e-16 59.5 0.0 2.0 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 ORY36540.1 - 3.2e-15 56.3 0.0 3.4e-12 46.4 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 ORY36540.1 - 4e-08 33.4 0.0 1.2e-07 31.8 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 ORY36540.1 - 6.5e-06 26.2 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 ORY36540.1 - 2.4e-05 24.1 0.1 7.2e-05 22.6 0.0 1.9 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 ORY36540.1 - 9.2e-05 22.7 0.0 0.00021 21.5 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain DUF815 PF05673.13 ORY36540.1 - 0.00022 20.5 0.0 0.00035 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 ORY36540.1 - 0.00024 21.0 0.0 0.00047 20.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY36540.1 - 0.0004 20.7 0.2 0.28 11.5 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_7 PF12775.7 ORY36540.1 - 0.00046 19.8 0.0 0.0008 19.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 ORY36540.1 - 0.00054 20.4 0.0 0.0021 18.4 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 ORY36540.1 - 0.00067 19.4 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 ORY36540.1 - 0.0024 17.9 0.0 0.14 12.2 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 ORY36540.1 - 0.0035 17.1 0.0 0.0053 16.5 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 ORY36540.1 - 0.0037 17.2 0.0 0.0059 16.6 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 ORY36540.1 - 0.0041 17.5 0.3 0.6 10.4 0.0 2.7 1 1 2 3 3 3 1 AAA domain DEAD PF00270.29 ORY36540.1 - 0.0041 16.9 0.2 0.047 13.5 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 ORY36540.1 - 0.0044 16.8 0.0 0.012 15.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 ORY36540.1 - 0.0066 16.4 0.1 0.023 14.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 ORY36540.1 - 0.012 15.4 0.0 0.025 14.3 0.0 1.4 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 ORY36540.1 - 0.014 15.3 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 ORY36540.1 - 0.027 13.9 0.1 0.13 11.6 0.0 1.9 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 ORY36540.1 - 0.029 14.9 0.0 0.055 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 ORY36540.1 - 0.033 13.6 0.1 0.52 9.7 0.0 2.2 1 1 1 2 2 2 0 Bacterial TniB protein DNA_pol3_delta PF06144.13 ORY36540.1 - 0.035 13.9 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit TIP49 PF06068.13 ORY36540.1 - 0.064 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_25 PF13481.6 ORY36540.1 - 0.094 12.3 0.1 1.3 8.6 0.0 2.4 2 1 0 3 3 3 0 AAA domain DUF4106 PF13388.6 ORY36540.1 - 0.13 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) RNA_helicase PF00910.22 ORY36540.1 - 0.13 12.6 0.0 0.23 11.8 0.0 1.5 1 1 0 1 1 1 0 RNA helicase SHMT PF00464.19 ORY36543.1 - 5.6e-203 673.9 0.0 6.8e-203 673.6 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Microvir_H PF04687.12 ORY36543.1 - 0.039 13.3 0.2 0.058 12.8 0.2 1.2 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) Pkinase PF00069.25 ORY36544.1 - 7.9e-63 212.3 0.0 1e-62 211.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY36544.1 - 9.5e-34 116.8 0.0 1.3e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY36544.1 - 2.2e-09 37.1 0.0 3.5e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY36544.1 - 0.00055 19.3 0.2 0.00093 18.6 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 ORY36544.1 - 0.0052 15.8 0.2 0.011 14.7 0.2 1.5 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 ORY36544.1 - 0.096 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY36544.1 - 0.64 8.9 4.5 0.073 12.0 0.2 1.6 2 0 0 2 2 2 0 Haspin like kinase domain cNMP_binding PF00027.29 ORY36545.1 - 2.6e-20 72.3 1.2 5.7e-11 42.3 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 ORY36545.1 - 0.13 12.0 0.4 6.6 6.5 0.1 2.2 2 0 0 2 2 2 0 Cupin domain cNMP_binding PF00027.29 ORY36546.1 - 8.1e-17 61.1 0.2 9.7e-16 57.6 0.1 2.4 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 ORY36546.1 - 3.8e-06 26.3 11.4 6.8e-06 25.5 11.4 1.4 1 0 0 1 1 1 1 Ion transport protein Pkinase PF00069.25 ORY36547.1 - 6e-50 170.1 0.3 7.3e-50 169.8 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY36547.1 - 8.5e-31 107.2 0.3 1.1e-30 106.8 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY36547.1 - 3e-10 39.9 0.0 5.1e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY36547.1 - 4.7e-05 22.9 0.1 6.5e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY36547.1 - 0.00048 19.2 0.6 0.00064 18.8 0.6 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY36547.1 - 0.001 19.0 0.0 0.0014 18.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY36547.1 - 0.049 12.4 0.1 0.075 11.8 0.1 1.2 1 1 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 ORY36548.1 - 6.2e-62 209.3 0.1 9.6e-62 208.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY36548.1 - 6.2e-33 114.2 0.0 9e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY36548.1 - 1.2e-09 37.9 0.0 1.9e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY36548.1 - 0.00067 19.1 0.0 0.0013 18.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY36548.1 - 0.0082 15.1 0.2 0.015 14.3 0.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY36548.1 - 0.023 14.6 0.0 0.055 13.4 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 ORY36548.1 - 0.035 13.7 0.4 1.7 8.2 0.1 2.5 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 ORY36548.1 - 0.052 12.3 2.3 0.23 10.2 0.0 2.5 2 1 1 3 3 3 0 Fungal protein kinase SPC12 PF06645.13 ORY36549.1 - 8e-29 99.5 1.0 9.5e-29 99.3 1.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MerC PF03203.14 ORY36549.1 - 0.028 14.9 0.2 0.029 14.8 0.2 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein DUF3040 PF11239.8 ORY36549.1 - 0.48 10.7 4.8 0.66 10.3 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) CRPA PF05745.11 ORY36549.1 - 1.7 8.7 6.7 3.1 7.8 6.7 1.4 1 1 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Pkinase PF00069.25 ORY36550.1 - 1e-64 218.5 0.0 1.5e-64 217.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY36550.1 - 1.7e-37 129.2 0.0 2.2e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY36550.1 - 1.5e-07 31.0 0.0 2.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY36550.1 - 0.00017 20.5 0.0 0.0004 19.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY36550.1 - 0.00063 18.8 0.5 0.001 18.1 0.5 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY36550.1 - 0.00069 19.0 0.3 0.0013 18.1 0.3 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY36550.1 - 0.00073 19.5 0.2 0.0012 18.8 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 ORY36550.1 - 0.016 14.8 0.2 0.33 10.5 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 ORY36551.1 - 2.5e-62 210.7 0.3 2.9e-62 210.4 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY36551.1 - 4.4e-34 117.9 0.1 5.7e-34 117.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY36551.1 - 7.4e-08 32.1 0.0 1.4e-07 31.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORY36551.1 - 0.00013 20.8 0.0 0.00021 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY36551.1 - 0.00043 19.3 0.2 0.00062 18.8 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY36551.1 - 0.0022 17.4 0.1 0.0032 16.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY36551.1 - 0.023 14.7 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 ORY36551.1 - 0.025 13.6 0.1 0.041 12.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Mg_trans_NIPA PF05653.14 ORY36553.1 - 8e-67 225.4 4.4 9.6e-67 225.2 4.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORY36553.1 - 2.9e-07 30.7 5.1 2.9e-07 30.7 5.1 3.0 3 0 0 3 3 3 2 EamA-like transporter family LMBR1 PF04791.16 ORY36553.1 - 0.0036 16.3 0.6 0.007 15.3 0.6 1.4 1 0 0 1 1 1 1 LMBR1-like membrane protein SLC35F PF06027.12 ORY36553.1 - 0.016 14.7 1.3 0.024 14.1 0.8 1.4 1 1 0 1 1 1 0 Solute carrier family 35 DUF4229 PF14012.6 ORY36553.1 - 5 7.3 6.4 9.2 6.4 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) DUF2226 PF09987.9 ORY36554.1 - 0.03 13.7 0.2 0.064 12.6 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) APC_rep PF18797.1 ORY36554.1 - 0.16 12.9 0.2 12 6.9 0.1 2.5 2 0 0 2 2 2 0 Adenomatous polyposis coli (APC) repeat Git3 PF11710.8 ORY36556.1 - 0.00057 19.7 3.3 0.00083 19.2 3.3 1.1 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 ORY36556.1 - 0.11 11.6 2.0 0.15 11.2 2.0 1.1 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 ORY36556.1 - 0.12 11.7 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF792 PF05632.11 ORY36558.1 - 0.05 13.5 0.1 0.078 12.9 0.1 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF792) FUSC-like PF12805.7 ORY36559.1 - 0.21 10.6 8.6 0.021 13.9 3.0 1.9 1 1 1 2 2 2 0 FUSC-like inner membrane protein yccS COPI_assoc PF08507.10 ORY36560.1 - 0.14 12.2 0.0 0.14 12.2 0.0 2.1 2 1 0 2 2 2 0 COPI associated protein DUF4293 PF14126.6 ORY36560.1 - 0.26 11.5 3.7 4.3 7.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) DUF4282 PF14110.6 ORY36560.1 - 1.4 9.7 6.6 6.8 7.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Cytochrom_B561 PF03188.16 ORY36561.1 - 2.7e-09 37.3 6.4 2.7e-09 37.3 6.4 2.2 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 ORY36561.1 - 8.9e-05 22.2 6.6 0.16 11.8 0.0 3.5 2 1 2 4 4 4 3 Domain of unknown function (DUF2427) MARVEL PF01284.23 ORY36561.1 - 0.0001 22.4 11.2 0.002 18.2 6.9 2.1 2 0 0 2 2 2 2 Membrane-associating domain Virul_fac_BrkB PF03631.15 ORY36561.1 - 0.016 14.8 9.6 0.098 12.3 1.3 2.1 1 1 1 2 2 2 0 Virulence factor BrkB dsrm PF00035.26 ORY36562.1 - 0.023 15.4 0.0 0.065 14.0 0.0 1.8 1 1 0 1 1 1 0 Double-stranded RNA binding motif HA2 PF04408.23 ORY36563.1 - 4.7e-20 71.9 0.0 9.1e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ORY36563.1 - 1.3e-16 60.9 0.0 2.9e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY36563.1 - 1.8e-10 40.9 0.0 3.4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ORY36563.1 - 0.00019 21.7 0.3 0.00081 19.7 0.3 2.0 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 ORY36563.1 - 0.003 16.9 0.0 0.0071 15.7 0.0 1.6 1 0 0 1 1 1 1 KaiC AAA_19 PF13245.6 ORY36563.1 - 0.0039 17.5 0.0 0.0087 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 ORY36563.1 - 0.0044 17.6 0.1 0.01 16.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 ORY36563.1 - 0.036 14.6 0.0 0.076 13.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 ORY36563.1 - 0.068 13.1 0.0 0.19 11.6 0.0 1.8 1 1 0 1 1 1 0 NACHT domain Rad17 PF03215.15 ORY36563.1 - 0.095 12.6 0.3 0.33 10.9 0.0 2.0 3 0 0 3 3 3 0 Rad17 P-loop domain PhoH PF02562.16 ORY36563.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF3602 PF12223.8 ORY36563.1 - 0.11 13.2 0.0 0.25 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) T2SSE PF00437.20 ORY36563.1 - 0.11 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 ORY36563.1 - 0.12 12.0 0.0 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORY36563.1 - 0.14 11.9 0.0 0.45 10.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 ORY36563.1 - 0.16 11.8 0.2 0.49 10.3 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase F-box-like PF12937.7 ORY36564.1 - 3.6e-05 23.6 0.0 5.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORY36564.1 - 5e-05 23.1 0.3 0.00053 19.8 0.0 2.0 2 0 0 2 2 2 1 F-box Phage_BR0599 PF09356.10 ORY36620.1 - 0.023 15.0 0.0 0.72 10.2 0.0 2.4 2 0 0 2 2 2 0 Phage conserved hypothetical protein BR0599 AKAP7_NLS PF10469.9 ORY36620.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 AKAP7 2'5' RNA ligase-like domain RhoGAP PF00620.27 ORY36622.1 - 1.6e-35 122.2 0.0 3.2e-35 121.2 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 ORY36622.1 - 7.1e-12 45.8 0.0 1.4e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 ORY36622.1 - 1.7e-05 25.2 0.0 3.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain HOOK PF05622.12 ORY36622.1 - 0.14 10.3 0.2 0.2 9.8 0.2 1.1 1 0 0 1 1 1 0 HOOK protein DUF423 PF04241.15 ORY36623.1 - 0.0022 18.2 2.3 0.014 15.5 2.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF423) Ndc1_Nup PF09531.10 ORY36623.1 - 0.008 14.9 2.4 0.0087 14.8 2.4 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup SUIM_assoc PF16619.5 ORY36624.1 - 0.023 14.7 10.5 0.075 13.1 1.9 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SPRY PF00622.28 ORY36625.1 - 1.2e-06 28.7 0.0 2.4e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 SPRY domain TIR_2 PF13676.6 ORY36625.1 - 0.0053 17.4 0.0 0.018 15.6 0.0 1.9 2 0 0 2 2 2 1 TIR domain Agenet PF05641.12 ORY36625.1 - 0.0054 17.2 0.0 0.013 16.0 0.0 1.7 1 0 0 1 1 1 1 Agenet domain DUF4819 PF16090.5 ORY36625.1 - 0.081 13.0 0.3 0.2 11.7 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4819) DUF1635 PF07795.11 ORY36626.1 - 0.44 10.4 5.8 2.6 7.9 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Herpes_pp85 PF04637.12 ORY36626.1 - 4.8 5.5 7.4 8 4.7 7.4 1.4 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) TPR_10 PF13374.6 ORY36627.1 - 9.5e-33 111.2 0.3 1.6e-08 34.2 0.0 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 ORY36627.1 - 1.1e-32 112.1 2.4 7.2e-13 48.6 0.1 5.4 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 ORY36627.1 - 3e-09 36.3 9.2 0.1 12.5 0.2 6.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY36627.1 - 1.2e-07 31.4 12.2 0.053 13.8 0.2 7.6 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY36627.1 - 1.4e-07 31.0 11.2 1 9.5 0.2 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY36627.1 - 1.3e-05 24.9 10.2 1.6 9.0 0.1 6.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY36627.1 - 3.6e-05 24.2 7.3 3.8 8.1 0.2 5.8 4 2 1 5 5 5 2 Tetratricopeptide repeat PPR PF01535.20 ORY36627.1 - 5.3e-05 23.2 1.0 0.75 10.2 0.0 4.0 4 0 0 4 4 4 2 PPR repeat Sel1 PF08238.12 ORY36627.1 - 0.00011 22.8 8.3 2.1 9.2 0.0 6.2 6 0 0 6 6 6 1 Sel1 repeat TPR_17 PF13431.6 ORY36627.1 - 0.00044 20.4 7.9 4.8 7.8 0.0 5.8 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY36627.1 - 3.4 8.4 11.0 4.5 8.0 0.1 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat F-box-like PF12937.7 ORY36628.1 - 0.15 11.9 1.4 0.4 10.6 1.4 1.8 1 1 0 1 1 1 0 F-box-like Ank_2 PF12796.7 ORY36629.1 - 2.5e-28 98.5 0.0 4.2e-10 40.1 0.0 3.5 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY36629.1 - 1.3e-20 73.5 0.9 1.6e-06 28.5 0.1 5.1 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY36629.1 - 5.8e-18 63.1 3.8 0.014 15.8 0.0 8.2 9 0 0 9 9 9 5 Ankyrin repeat Ank PF00023.30 ORY36629.1 - 7.9e-16 57.7 5.9 0.0091 16.4 0.0 6.9 4 3 3 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 ORY36629.1 - 8.5e-11 41.9 8.8 0.051 13.9 0.0 6.8 2 2 6 8 8 8 5 Ankyrin repeats (many copies) DNA_pol_phi PF04931.13 ORY36629.1 - 2.4 6.2 6.2 3.5 5.6 6.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi Ank_2 PF12796.7 ORY36630.1 - 2.5e-39 133.7 1.0 5.6e-13 49.3 0.0 5.5 2 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY36630.1 - 1.1e-21 76.9 2.3 8.2e-05 23.1 0.0 6.6 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY36630.1 - 7.6e-20 68.9 1.3 0.14 12.8 0.0 10.3 10 0 0 10 10 10 4 Ankyrin repeat Ank_5 PF13857.6 ORY36630.1 - 2.5e-19 69.1 4.9 0.00075 19.8 0.0 8.5 2 2 8 10 10 10 5 Ankyrin repeats (many copies) Ank PF00023.30 ORY36630.1 - 1.3e-12 47.6 1.1 0.22 12.0 0.0 8.6 5 3 2 7 7 7 3 Ankyrin repeat HEAT PF02985.22 ORY36630.1 - 1.2e-06 28.3 0.0 0.027 14.7 0.0 3.5 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.6 ORY36630.1 - 7.3e-05 23.1 0.0 0.0011 19.3 0.0 3.0 2 0 0 2 2 2 1 HEAT repeats MMS19_N PF14500.6 ORY36630.1 - 0.047 13.3 0.0 1.7 8.2 0.0 2.7 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II F-box-like PF12937.7 ORY36630.1 - 0.18 11.7 0.6 0.57 10.1 0.6 1.9 1 0 0 1 1 1 0 F-box-like DUF4637 PF15470.6 ORY36630.1 - 0.81 9.4 6.5 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) Ima1_N PF09779.9 ORY36631.1 - 0.0013 19.6 0.6 0.0026 18.6 0.6 1.5 1 1 0 1 1 1 1 Ima1 N-terminal domain Yippee-Mis18 PF03226.14 ORY36631.1 - 0.079 13.2 0.1 0.21 11.8 0.1 1.6 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Ank_2 PF12796.7 ORY36632.1 - 1.5e-14 54.3 0.0 5.1e-08 33.4 0.0 2.2 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY36632.1 - 2.9e-09 37.0 0.3 0.2 12.0 0.0 4.1 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY36632.1 - 1.9e-07 30.8 0.2 0.45 11.2 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 ORY36632.1 - 8.4e-06 26.2 0.1 0.18 12.4 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY36632.1 - 1.4e-05 25.3 0.3 0.46 11.0 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat rve_3 PF13683.6 ORY36634.1 - 0.088 12.6 1.4 0.19 11.5 0.1 2.2 3 0 0 3 3 3 0 Integrase core domain DUF659 PF04937.15 ORY36635.1 - 1.7e-08 34.5 0.0 2.6e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) F-box-like PF12937.7 ORY36636.1 - 0.0012 18.7 0.1 0.0021 17.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like DUF2738 PF10927.8 ORY36636.1 - 0.025 13.7 0.1 0.031 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) F-box PF00646.33 ORY36636.1 - 0.074 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 F-box domain ARID PF01388.21 ORY36637.1 - 8.1e-18 64.9 1.1 1.6e-17 63.9 0.1 2.0 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 ORY36637.1 - 0.14 11.5 0.5 0.38 10.0 0.2 1.9 1 1 0 1 1 1 0 SWI/SNF-like complex subunit BAF250/Osa Activator_LAG-3 PF11498.8 ORY36637.1 - 0.21 10.5 14.4 0.4 9.6 14.4 1.4 1 0 0 1 1 1 0 Transcriptional activator LAG-3 AT_hook PF02178.19 ORY36637.1 - 3.5 7.8 8.8 0.05 13.5 1.0 2.3 2 0 0 2 2 2 0 AT hook motif Aldo_ket_red PF00248.21 ORY36638.1 - 1.9e-44 152.0 0.0 2.2e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ank_2 PF12796.7 ORY36639.1 - 6.8e-28 97.1 0.0 8.2e-12 45.6 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY36639.1 - 6e-20 71.1 0.2 0.00075 19.7 0.0 6.5 2 1 5 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY36639.1 - 4.5e-18 65.4 0.1 6.3e-05 23.5 0.0 4.8 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY36639.1 - 2.2e-17 61.4 0.0 0.27 11.9 0.0 7.5 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 ORY36639.1 - 1.6e-12 47.3 0.1 0.44 11.1 0.0 6.3 6 0 0 6 6 6 3 Ankyrin repeat DUF1281 PF06924.11 ORY36639.1 - 0.034 13.7 0.5 0.067 12.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) tRNA_U5-meth_tr PF05958.11 ORY36640.1 - 3.3e-16 59.2 0.0 3.1e-14 52.8 0.0 2.9 3 0 0 3 3 3 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 ORY36640.1 - 6.2e-06 26.1 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY36640.1 - 3.9e-05 24.3 0.0 0.00018 22.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY36640.1 - 0.00059 20.4 0.0 0.0019 18.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 ORY36640.1 - 0.0017 17.8 0.0 0.0026 17.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.16 ORY36640.1 - 0.0056 16.5 0.0 0.0095 15.7 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_15 PF09445.10 ORY36640.1 - 0.0068 16.0 0.0 0.024 14.2 0.0 1.9 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_4 PF02390.17 ORY36640.1 - 0.049 13.1 0.0 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase Acyl-CoA_dh_1 PF00441.24 ORY36641.1 - 9.6e-46 155.7 1.0 1.3e-45 155.3 1.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY36641.1 - 1.7e-23 82.6 0.0 5.9e-23 80.9 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY36641.1 - 3.1e-20 72.8 0.1 4.6e-20 72.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY36641.1 - 2.7e-18 66.7 0.0 7.7e-18 65.2 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Ribosomal_L1 PF00687.21 ORY36642.1 - 1.1e-27 97.1 0.0 1.4e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family AAA PF00004.29 ORY36643.1 - 1.7e-30 106.1 0.1 8.6e-21 74.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY36643.1 - 7.3e-09 35.3 0.2 0.00011 22.0 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain Vps4_C PF09336.10 ORY36643.1 - 0.019 15.0 0.3 0.74 9.9 0.0 3.0 2 1 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_16 PF13191.6 ORY36643.1 - 0.034 14.5 0.0 16 5.9 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 ORY36643.1 - 0.11 12.0 0.0 0.89 9.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region ALAD PF00490.21 ORY36646.1 - 4.2e-107 358.0 0.0 4.8e-107 357.8 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase LRR_8 PF13855.6 ORY36647.1 - 3.2e-17 62.0 20.6 0.00096 18.9 1.8 5.6 4 2 1 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 ORY36647.1 - 9.8e-13 48.1 25.0 0.001 19.4 3.0 6.0 3 3 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY36647.1 - 1.2e-06 28.2 23.2 2.1 9.2 0.1 9.1 9 0 0 9 9 9 3 Leucine Rich Repeat LRR_6 PF13516.6 ORY36647.1 - 2.6 8.3 14.2 3.6 7.9 0.3 5.4 6 0 0 6 6 6 0 Leucine Rich repeat LRR_9 PF14580.6 ORY36647.1 - 4.9 6.6 6.4 16 5.0 0.4 3.2 2 2 1 3 3 3 0 Leucine-rich repeat ABC_tran PF00005.27 ORY36648.1 - 2e-44 151.5 2.3 2.5e-32 112.3 0.1 3.0 2 1 1 3 3 3 2 ABC transporter ABC_membrane PF00664.23 ORY36648.1 - 1.7e-32 113.1 20.5 7.7e-18 65.1 7.5 2.9 2 2 0 2 2 2 2 ABC transporter transmembrane region AAA_29 PF13555.6 ORY36648.1 - 3.9e-10 39.3 4.2 2.3e-05 24.0 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY36648.1 - 2.5e-07 31.2 1.1 0.11 12.9 0.3 3.4 2 1 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 ORY36648.1 - 2.9e-07 30.6 0.7 0.017 15.2 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 ORY36648.1 - 6.9e-06 26.1 3.6 0.059 13.2 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ORY36648.1 - 1.6e-05 25.5 5.1 0.057 13.9 0.6 2.7 3 0 0 3 3 2 2 AAA domain DUF87 PF01935.17 ORY36648.1 - 1.9e-05 24.8 6.4 0.0038 17.4 0.1 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain T2SSE PF00437.20 ORY36648.1 - 3.6e-05 22.9 3.4 0.084 11.9 0.1 3.1 3 0 0 3 3 3 2 Type II/IV secretion system protein SMC_N PF02463.19 ORY36648.1 - 7.9e-05 22.2 6.0 0.29 10.6 0.4 3.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 ORY36648.1 - 9.7e-05 21.7 2.8 0.11 11.8 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 ORY36648.1 - 0.00022 21.2 3.2 0.25 11.2 0.5 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 ORY36648.1 - 0.00032 20.3 1.5 1.1 8.7 0.0 3.2 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_22 PF13401.6 ORY36648.1 - 0.00081 19.7 5.2 0.65 10.3 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 ORY36648.1 - 0.00088 19.0 6.7 0.25 11.0 0.1 2.9 3 0 0 3 3 3 2 AAA domain TrwB_AAD_bind PF10412.9 ORY36648.1 - 0.002 17.1 5.4 0.33 9.8 0.2 2.9 3 0 0 3 3 3 2 Type IV secretion-system coupling protein DNA-binding domain AAA_15 PF13175.6 ORY36648.1 - 0.0024 17.6 1.2 1.6 8.3 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.22 ORY36648.1 - 0.0028 18.0 0.4 8.5 6.8 0.0 3.5 4 0 0 4 4 3 0 RNA helicase FtsK_SpoIIIE PF01580.18 ORY36648.1 - 0.0039 16.6 4.4 0.67 9.3 0.3 2.6 3 0 0 3 3 3 2 FtsK/SpoIIIE family MeaB PF03308.16 ORY36648.1 - 0.004 16.2 3.1 0.38 9.7 0.1 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 ORY36648.1 - 0.0048 16.8 3.5 1.5 8.7 0.4 3.1 3 0 0 3 3 3 1 NACHT domain Roc PF08477.13 ORY36648.1 - 0.0051 17.0 1.0 5.2 7.3 0.1 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 ORY36648.1 - 0.0055 15.9 1.3 1.2 8.2 0.1 2.8 3 0 0 3 3 2 1 NB-ARC domain Ploopntkinase3 PF18751.1 ORY36648.1 - 0.0057 16.6 0.7 1.7 8.5 0.2 2.4 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 cobW PF02492.19 ORY36648.1 - 0.0081 15.8 1.1 4.2 6.9 0.1 2.9 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 ORY36648.1 - 0.034 13.9 3.9 0.59 9.9 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.25 ORY36648.1 - 0.045 13.4 0.5 2 8.0 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 ORY36648.1 - 0.048 14.2 0.3 14 6.2 0.1 3.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ORY36648.1 - 0.062 13.0 1.9 0.64 9.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.13 ORY36648.1 - 0.09 11.9 1.1 9 5.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Dynamin_N PF00350.23 ORY36648.1 - 0.1 12.7 10.6 0.18 11.8 1.0 3.0 4 0 0 4 4 2 0 Dynamin family AAA_33 PF13671.6 ORY36648.1 - 0.13 12.5 2.4 12 6.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain AWPM-19 PF05512.11 ORY36648.1 - 0.13 12.5 0.1 0.13 12.5 0.1 3.5 4 1 0 4 4 3 0 AWPM-19-like family GBP PF02263.19 ORY36648.1 - 0.19 11.0 1.1 48 3.1 0.1 3.2 3 0 0 3 3 3 0 Guanylate-binding protein, N-terminal domain PIF1 PF05970.14 ORY36648.1 - 0.31 10.2 5.0 4.2 6.5 0.1 2.6 3 0 0 3 3 2 0 PIF1-like helicase AAA_25 PF13481.6 ORY36648.1 - 0.34 10.5 3.7 2.1 7.9 1.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ORY36648.1 - 0.37 11.0 2.4 25 5.0 1.6 2.6 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 ORY36648.1 - 0.79 9.4 3.5 3.8 7.2 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.10 ORY36648.1 - 1.6 8.1 3.3 4.5 6.7 0.0 2.9 4 0 0 4 4 3 0 Chromatin associated protein KTI12 ABC_ATPase PF09818.9 ORY36648.1 - 2.6 6.7 6.2 0.75 8.5 0.3 2.8 4 0 0 4 4 3 0 Predicted ATPase of the ABC class DEAD PF00270.29 ORY36648.1 - 3.4 7.4 8.3 14 5.4 1.2 3.5 3 1 0 3 3 2 0 DEAD/DEAH box helicase DUF2101 PF09874.9 ORY36648.1 - 8.1 6.1 11.6 0.19 11.4 4.2 2.0 2 0 0 2 2 1 0 Predicted membrane protein (DUF2101) zf-C2H2_4 PF13894.6 ORY36650.1 - 0.0081 16.9 10.3 0.16 12.9 0.3 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY36650.1 - 0.012 15.6 1.0 0.62 10.1 0.0 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY36650.1 - 0.026 15.0 11.9 0.12 12.9 0.0 3.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY36651.1 - 1.1e-05 25.8 1.1 0.4 11.6 0.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY36651.1 - 8.2e-05 22.9 4.1 0.024 15.1 0.0 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.7 ORY36651.1 - 0.022 15.2 0.2 20 5.8 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type HTH_23 PF13384.6 ORY36654.1 - 9.1e-06 25.3 4.1 1.2e-05 25.0 0.9 2.4 2 1 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.18 ORY36654.1 - 5e-05 23.5 0.0 0.0001 22.5 0.0 1.5 1 0 0 1 1 1 1 Transposase HTH_32 PF13565.6 ORY36654.1 - 0.0043 17.6 0.7 0.0069 17.0 0.6 1.4 1 1 0 1 1 1 1 Homeodomain-like domain HTH_33 PF13592.6 ORY36654.1 - 0.0046 16.6 0.1 0.0074 15.9 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 ORY36654.1 - 0.0051 16.9 1.8 0.0079 16.3 0.9 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_21 PF13276.6 ORY36654.1 - 0.02 15.0 0.5 0.25 11.5 0.0 2.2 2 0 0 2 2 2 0 HTH-like domain HTH_Tnp_IS630 PF01710.16 ORY36654.1 - 0.12 12.4 0.1 0.15 12.1 0.1 1.3 1 1 0 1 1 1 0 Transposase ZZ PF00569.17 ORY36654.1 - 0.35 10.7 2.4 1.4 8.8 0.2 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type DDE_3 PF13358.6 ORY36655.1 - 9.4e-09 35.2 0.0 1.8e-08 34.3 0.0 1.4 1 1 1 2 2 2 1 DDE superfamily endonuclease Ank_2 PF12796.7 ORY36658.1 - 6.5e-44 148.4 0.0 4.8e-12 46.3 0.0 4.2 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY36658.1 - 6.4e-23 80.5 4.2 0.0092 16.3 0.1 8.2 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY36658.1 - 9.9e-22 77.0 0.2 4.7e-05 23.9 0.0 5.4 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY36658.1 - 3.2e-20 70.1 1.7 0.076 13.6 0.0 8.6 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 ORY36658.1 - 2e-15 56.4 0.5 0.6 10.6 0.1 7.8 6 2 2 8 8 8 5 Ankyrin repeat VWA_3_C PF18571.1 ORY36658.1 - 6.7e-06 25.9 0.4 0.26 11.2 0.0 4.6 4 1 1 5 5 5 1 von Willebrand factor type A C-terminal domain ERAP1_C PF11838.8 ORY36658.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 ERAP1-like C-terminal domain Arrestin_N PF00339.29 ORY36659.1 - 1.8e-14 54.0 0.0 4.7e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY36659.1 - 7.3e-05 23.2 7.6 0.00029 21.3 7.6 1.9 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 ORY36659.1 - 0.11 11.7 0.4 2.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Rgp1 DGF-1_C PF11040.8 ORY36659.1 - 0.62 10.1 2.4 3.3 7.8 0.0 3.0 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus KIAA1430 PF13879.6 ORY36660.1 - 4.6e-15 56.2 4.1 4.6e-15 56.2 4.1 3.6 4 0 0 4 4 4 1 KIAA1430 homologue WD40 PF00400.32 ORY36660.1 - 2.6e-09 37.6 9.8 3.6e-05 24.4 0.2 7.3 8 0 0 8 8 8 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY36660.1 - 4.9e-06 26.7 5.0 0.038 14.3 0.0 5.4 7 1 0 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain PHTB1_N PF14727.6 ORY36660.1 - 0.072 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 PTHB1 N-terminus Lgl_C PF08596.10 ORY36660.1 - 0.074 11.7 0.5 0.14 10.8 0.5 1.3 1 0 0 1 1 1 0 Lethal giant larvae(Lgl) like, C-terminal OstA PF03968.14 ORY36661.1 - 0.017 15.3 0.1 4.9 7.4 0.2 2.1 1 1 1 2 2 2 0 OstA-like protein DUF4326 PF14216.6 ORY36662.1 - 3.1e-11 43.8 0.0 4.5e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4326) DUF1349 PF07081.11 ORY36663.1 - 4.3e-27 95.0 0.3 4.8e-27 94.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) CN_hydrolase PF00795.22 ORY36664.1 - 5.1e-37 127.6 0.0 7.9e-37 127.0 0.0 1.2 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase zf-C2H2_aberr PF17017.5 ORY36666.1 - 0.0013 19.0 1.0 0.013 15.7 0.0 2.6 2 0 0 2 2 2 1 Aberrant zinc-finger zf-C2H2_4 PF13894.6 ORY36666.1 - 0.0027 18.4 5.9 0.036 14.9 0.8 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY36666.1 - 0.0044 17.4 4.6 0.065 13.7 1.1 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type Zn_clus PF00172.18 ORY36666.1 - 0.032 14.4 14.3 0.023 14.8 4.9 2.8 2 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 ORY36667.1 - 0.07 14.0 1.1 0.14 13.1 1.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Zn_clus PF00172.18 ORY36668.1 - 4.2e-10 39.6 18.8 9.2e-10 38.5 6.1 2.7 2 1 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain FA_hydroxylase PF04116.13 ORY36670.1 - 2.2e-24 86.3 14.7 2.5e-24 86.1 14.7 1.0 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Vma12 PF11712.8 ORY36670.1 - 0.065 13.3 0.4 2.3 8.3 0.1 2.1 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase CRAL_TRIO PF00650.20 ORY36671.1 - 1e-23 83.8 0.0 1.9e-23 82.9 0.0 1.5 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORY36671.1 - 1.3e-06 28.5 0.1 2.7e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ORY36671.1 - 0.038 14.1 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF963 PF06131.11 ORY36672.1 - 2.7 7.5 6.0 1.7 8.1 2.9 2.3 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) zf-C2H2 PF00096.26 ORY36673.1 - 8.5e-12 44.8 11.5 0.0045 17.4 0.3 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY36673.1 - 9.8e-11 41.6 10.4 0.012 16.4 0.2 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY36673.1 - 3.3e-05 23.8 5.7 0.055 13.5 0.0 3.5 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORY36673.1 - 0.0009 19.4 1.3 0.38 10.9 0.0 2.9 1 1 2 3 3 3 1 Aberrant zinc-finger zf-met PF12874.7 ORY36673.1 - 0.0012 19.2 2.0 1.5 9.3 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 ORY36673.1 - 0.0037 17.5 0.8 0.0041 17.4 0.8 1.1 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 ORY36673.1 - 0.01 16.2 0.1 0.01 16.2 0.1 3.5 4 0 0 4 4 4 0 Zinc-finger double domain zf_ZIC PF18366.1 ORY36673.1 - 0.029 14.5 2.7 4.7 7.4 0.2 2.8 2 1 1 3 3 3 0 Zic proteins zinc finger domain FOXP-CC PF16159.5 ORY36673.1 - 0.029 15.0 2.0 6.4 7.5 0.4 2.2 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 ORY36673.1 - 0.041 14.2 6.7 2.5 8.5 0.8 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 ORY36673.1 - 0.2 11.6 0.3 0.2 11.6 0.3 3.1 3 0 0 3 3 3 0 zinc-finger of a C2HC-type MamL-1 PF09596.10 ORY36673.1 - 1.1 9.5 5.8 5.5 7.3 0.0 2.8 2 1 1 3 3 3 0 MamL-1 domain ADH_zinc_N PF00107.26 ORY36674.1 - 1.7e-22 79.8 0.4 2.5e-22 79.2 0.4 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY36674.1 - 3.8e-13 50.6 0.0 6.6e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY36674.1 - 3.6e-07 30.1 0.0 1.7e-06 27.9 0.0 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.10 ORY36674.1 - 0.081 13.1 0.7 0.17 12.1 0.7 1.5 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Cys_Met_Meta_PP PF01053.20 ORY36675.1 - 3.1e-97 325.5 0.2 2.9e-48 164.3 0.0 2.0 1 1 1 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ORY36675.1 - 0.0026 17.0 0.1 0.0033 16.7 0.1 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ORY36675.1 - 0.04 13.2 0.3 0.067 12.5 0.3 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3646 PF12362.8 ORY36675.1 - 0.18 12.1 0.0 5.6 7.3 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase III gamma and tau subunits C terminal LRR_8 PF13855.6 ORY36676.1 - 1.7e-13 50.1 17.7 1.3e-08 34.4 3.5 4.2 3 2 1 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 ORY36676.1 - 9.8e-09 35.4 22.9 0.012 16.1 1.2 5.7 3 2 2 6 6 6 4 Leucine Rich repeats (2 copies) F-box PF00646.33 ORY36676.1 - 0.00052 19.8 0.2 0.001 18.9 0.2 1.4 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.33 ORY36676.1 - 0.0027 18.0 22.1 2.5 9.0 0.0 7.5 7 1 1 8 8 8 2 Leucine Rich Repeat LRR_9 PF14580.6 ORY36676.1 - 0.043 13.3 3.3 4 6.9 0.2 2.3 1 1 1 2 2 2 0 Leucine-rich repeat F-box-like PF12937.7 ORY36676.1 - 0.074 13.0 0.2 0.074 13.0 0.2 1.8 2 0 0 2 2 2 0 F-box-like Methyltransf_32 PF13679.6 ORY36677.1 - 2.5e-24 86.1 0.1 4.1e-24 85.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY36677.1 - 0.0033 17.0 0.0 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 ORY36677.1 - 0.027 14.2 0.1 0.086 12.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DREV PF05219.12 ORY36677.1 - 0.056 12.5 0.0 0.15 11.1 0.0 1.6 2 0 0 2 2 2 0 DREV methyltransferase TRM13 PF05206.14 ORY36677.1 - 0.082 12.4 0.4 0.18 11.3 0.4 1.5 1 1 0 1 1 1 0 Methyltransferase TRM13 RrnaAD PF00398.20 ORY36677.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF966 PF06136.13 ORY36677.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) F-box-like PF12937.7 ORY36678.1 - 4.7e-05 23.2 0.1 7e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY36678.1 - 0.022 14.6 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 F-box domain COPI_assoc PF08507.10 ORY36679.1 - 5.7e-07 29.6 7.1 6.8e-07 29.4 7.1 1.2 1 0 0 1 1 1 1 COPI associated protein FA_desaturase PF00487.24 ORY36681.1 - 8.7e-18 65.1 18.4 8.7e-18 65.1 18.4 1.6 1 1 1 2 2 2 2 Fatty acid desaturase Cyt-b5 PF00173.28 ORY36681.1 - 1e-14 54.4 0.0 2.4e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Zn_clus PF00172.18 ORY36682.1 - 1.6e-15 57.0 26.8 6.7e-09 35.7 8.1 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 ORY36682.1 - 0.0043 16.8 6.6 0.76 9.6 0.4 2.9 2 0 0 2 2 2 2 Integrin plexin domain UMPH-1 PF05822.12 ORY36683.1 - 8.5e-58 195.8 0.3 9.4e-58 195.6 0.3 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 ORY36683.1 - 4.2e-07 30.6 0.0 6.2e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Complex1_LYR PF05347.15 ORY36685.1 - 3.7e-16 58.9 0.2 5.8e-16 58.3 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 ORY36685.1 - 0.00017 22.3 0.0 0.00021 22.0 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Thioredoxin PF00085.20 ORY36686.1 - 1.2e-24 86.2 0.0 1.4e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY36686.1 - 4.1e-08 33.7 0.1 7.7e-08 32.8 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORY36686.1 - 3e-05 24.2 0.1 0.00019 21.7 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 ORY36686.1 - 0.00019 21.5 0.1 0.00033 20.8 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 ORY36686.1 - 0.00022 20.7 0.0 0.00022 20.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_3 PF13192.6 ORY36686.1 - 0.00022 21.2 0.0 0.00029 20.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.21 ORY36686.1 - 0.013 15.5 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family DUF3908 PF13048.6 ORY36686.1 - 0.029 14.6 0.1 0.038 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3908) DUF836 PF05768.14 ORY36686.1 - 0.029 14.8 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) TraF PF13728.6 ORY36686.1 - 0.064 13.1 0.0 0.082 12.7 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein HyaE PF07449.11 ORY36686.1 - 0.067 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 ORY36686.1 - 0.074 12.8 0.6 0.13 12.0 0.6 1.5 1 1 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.6 ORY36686.1 - 0.092 12.5 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Phosducin PF02114.16 ORY36686.1 - 0.16 10.9 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 Phosducin NIF PF03031.18 ORY36688.1 - 1.8e-25 89.6 0.0 7.6e-25 87.5 0.0 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Ank_2 PF12796.7 ORY36689.1 - 4.5e-27 94.5 0.0 2.4e-09 37.6 0.0 3.5 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY36689.1 - 1.8e-20 73.0 1.6 4.1e-05 24.1 0.0 5.1 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY36689.1 - 3.4e-20 71.8 0.7 0.00051 20.3 0.0 6.9 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY36689.1 - 4e-17 60.5 0.0 0.29 11.8 0.0 6.8 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 ORY36689.1 - 4.1e-15 55.4 0.1 0.81 10.3 0.0 7.3 5 2 2 7 7 7 4 Ankyrin repeat F-box-like PF12937.7 ORY36689.1 - 0.0021 17.9 0.3 0.0059 16.5 0.3 1.8 1 0 0 1 1 1 1 F-box-like VWA_3_C PF18571.1 ORY36689.1 - 0.014 15.2 0.2 0.065 13.1 0.1 2.3 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain DUF1110 PF06533.12 ORY36689.1 - 0.61 10.0 2.1 11 6.0 0.1 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1110) TPR_2 PF07719.17 ORY36690.1 - 5.7e-05 22.9 5.8 0.0065 16.5 0.2 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY36690.1 - 6e-05 23.4 1.8 0.035 14.7 0.0 2.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY36690.1 - 0.00033 20.6 2.5 0.0071 16.5 0.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY36690.1 - 0.00068 19.3 5.7 0.076 12.9 0.2 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY36690.1 - 0.0016 18.6 2.6 0.0033 17.6 2.7 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 ORY36690.1 - 0.0024 18.1 0.5 0.37 11.1 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY36690.1 - 0.0059 17.2 0.2 0.012 16.2 0.1 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY36690.1 - 0.018 15.0 1.4 0.72 10.0 0.1 3.0 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 ORY36690.1 - 0.019 15.1 0.3 0.32 11.2 0.2 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat Foie-gras_1 PF11817.8 ORY36690.1 - 0.02 14.5 0.1 0.12 11.9 0.1 1.9 2 0 0 2 2 2 0 Foie gras liver health family 1 TPR_14 PF13428.6 ORY36690.1 - 0.13 13.1 0.3 6.8 7.8 0.0 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF5448 PF17526.2 ORY36690.1 - 0.3 11.3 1.9 23 5.2 0.2 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5448) Cation_efflux PF01545.21 ORY36692.1 - 0.00034 20.4 0.0 0.00042 20.1 0.0 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORY36692.1 - 0.012 15.7 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter PI3_PI4_kinase PF00454.27 ORY36693.1 - 1.3e-37 130.0 0.0 1.1e-27 97.5 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 ORY36693.1 - 2e-26 92.5 0.9 3.7e-26 91.7 0.2 1.7 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF3007 PF11460.8 ORY36695.1 - 0.0078 16.4 0.3 0.0096 16.2 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3007) DUF2834 PF11196.8 ORY36697.1 - 0.007 16.7 16.8 0.074 13.4 1.5 3.5 2 1 0 2 2 2 2 Protein of unknown function (DUF2834) zf-C2H2_6 PF13912.6 ORY36700.1 - 0.015 15.3 5.3 0.14 12.2 0.4 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 ORY36700.1 - 1.2 9.5 8.2 0.81 10.1 0.8 3.6 4 0 0 4 4 4 0 C2H2 type zinc-finger (2 copies) TTL PF03133.15 ORY36702.1 - 1e-92 310.5 1.1 1.1e-92 310.3 1.1 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 ORY36702.1 - 1.9e-07 30.6 0.1 0.00021 20.6 0.0 2.4 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 ORY36702.1 - 5.4e-05 22.6 0.0 0.083 12.1 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp EamA PF00892.20 ORY36703.1 - 3.2e-06 27.4 26.6 0.00069 19.8 10.1 3.9 2 2 1 3 3 3 2 EamA-like transporter family TPT PF03151.16 ORY36703.1 - 8.9e-05 22.0 11.8 0.0047 16.3 2.8 2.3 1 1 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 ORY36703.1 - 0.00019 20.7 1.9 0.00044 19.5 1.9 1.6 1 0 0 1 1 1 1 Nucleotide-sugar transporter Ank_2 PF12796.7 ORY36704.1 - 1.9e-16 60.4 0.6 8.3e-11 42.3 0.0 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY36704.1 - 4.8e-11 41.9 6.7 0.0063 16.9 0.0 5.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 ORY36704.1 - 4e-09 36.6 8.8 0.019 15.3 0.1 4.7 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY36704.1 - 3.5e-07 30.6 1.7 0.0056 17.2 0.1 3.5 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY36704.1 - 1.4e-06 28.5 4.1 2.3 8.8 0.0 5.2 3 1 1 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 ORY36705.1 - 4.9e-08 33.5 0.0 3e-06 27.7 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY36705.1 - 0.00058 20.1 0.1 0.38 11.5 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeat F-box-like PF12937.7 ORY36705.1 - 0.0017 18.2 0.1 0.0045 16.8 0.0 1.7 2 0 0 2 2 2 1 F-box-like Ank_4 PF13637.6 ORY36705.1 - 0.0042 17.6 0.1 0.037 14.6 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY36705.1 - 0.0081 16.5 0.0 3.8 7.9 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) HEAT_2 PF13646.6 ORY36706.1 - 6.8e-15 55.2 12.6 6e-05 23.3 0.5 2.9 1 1 3 4 4 4 4 HEAT repeats EF-G-binding_N PF07299.11 ORY36706.1 - 1.4e-10 41.5 17.2 0.29 11.7 0.1 6.0 2 1 4 6 6 6 5 Elongation factor G-binding protein, N-terminal FliC_SP PF12613.8 ORY36706.1 - 5.1e-09 36.5 32.3 0.099 13.2 0.6 6.3 6 0 0 6 6 6 3 Flagellin structural protein DUF349 PF03993.12 ORY36706.1 - 3.5e-07 30.4 1.1 4 7.8 0.0 5.3 6 0 0 6 6 5 1 Domain of Unknown Function (DUF349) TTRAP PF14203.6 ORY36706.1 - 7e-06 25.9 0.6 1.1 9.3 0.0 5.4 4 2 2 6 6 6 1 Putative tranposon-transfer assisting protein TilS PF09179.11 ORY36706.1 - 8.8e-06 26.1 1.1 4.4 7.9 0.0 4.9 1 1 4 5 5 5 1 TilS substrate binding domain bPH_4 PF06713.11 ORY36706.1 - 2.7e-05 24.2 1.8 0.12 12.4 0.1 3.8 1 1 4 5 5 5 1 Bacterial PH domain NapD PF03927.13 ORY36706.1 - 0.00073 19.5 4.3 1.8 8.6 0.0 4.0 3 1 1 4 4 4 2 NapD protein Herpes_UL1 PF05259.11 ORY36706.1 - 0.00097 19.2 0.6 1 9.5 0.0 2.9 2 1 0 3 3 3 1 Herpesvirus glycoprotein L RVT_thumb PF06817.14 ORY36706.1 - 0.0013 18.5 2.0 5 7.0 0.1 4.3 3 2 2 5 5 5 1 Reverse transcriptase thumb domain EH_Signature PF15611.6 ORY36706.1 - 0.0023 17.4 0.2 0.019 14.4 0.2 2.1 1 1 0 1 1 1 1 EH_Signature domain Casc1_N PF15927.5 ORY36706.1 - 0.01 15.5 0.2 7.2 6.2 0.1 2.9 1 1 1 2 2 2 0 Cancer susceptibility candidate 1 N-terminus DnaB_bind PF10410.9 ORY36706.1 - 0.014 15.6 4.2 68 3.8 0.0 5.2 6 0 0 6 6 6 0 DnaB-helicase binding domain of primase PUB_1 PF18486.1 ORY36706.1 - 0.016 15.0 10.8 18 5.3 0.0 5.5 2 2 4 6 6 6 0 PNGase/UBA- or UBX-containing domain DUF4192 PF13830.6 ORY36706.1 - 0.017 15.2 0.0 0.11 12.5 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4192) LegC3_N PF18654.1 ORY36706.1 - 0.017 14.3 0.2 1.8 7.7 0.0 2.3 1 1 0 2 2 2 0 LegC3 N-terminal coiled-coil domain Ter PF05472.11 ORY36706.1 - 0.021 13.8 3.0 0.5 9.3 0.0 2.8 1 1 2 3 3 3 0 DNA replication terminus site-binding protein (Ter protein) DUF4844 PF16133.5 ORY36706.1 - 0.023 15.3 2.9 32 5.1 0.0 4.4 2 1 3 5 5 5 0 Domain of unknown function (DUF4844) Herpes_U34 PF04541.13 ORY36706.1 - 0.028 13.7 0.8 13 4.9 0.0 3.3 1 1 1 3 3 3 0 Herpesvirus virion protein U34 Dynactin_p22 PF07426.11 ORY36706.1 - 0.03 14.2 4.5 0.12 12.3 2.9 2.4 1 1 1 2 2 2 0 Dynactin subunit p22 VASt PF16016.5 ORY36706.1 - 0.065 13.6 0.2 10 6.5 0.0 2.6 1 1 1 2 2 2 0 VAD1 Analog of StAR-related lipid transfer domain CdiI_2 PF18593.1 ORY36706.1 - 0.15 12.7 0.0 17 6.1 0.0 3.8 1 1 3 5 5 5 0 CdiI immunity protein Yuri_gagarin PF15934.5 ORY36706.1 - 0.21 11.4 0.6 3.6 7.4 0.7 2.6 1 1 0 1 1 1 0 Yuri gagarin TraH_2 PF06871.11 ORY36706.1 - 0.22 11.1 2.4 5.9 6.5 0.1 2.8 2 2 1 3 3 3 0 TraH_2 DUF4290 PF14123.6 ORY36706.1 - 0.51 9.9 2.2 17 4.9 0.1 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4290) FliT PF05400.13 ORY36706.1 - 0.62 10.9 3.6 38 5.2 1.4 3.8 2 2 1 3 3 3 0 Flagellar protein FliT HiaBD2 PF15403.6 ORY36706.1 - 1.7 9.1 7.9 21 5.6 0.1 3.8 5 0 0 5 5 3 0 HiaBD2_N domain of Trimeric autotransporter adhesin (GIN) LIP1 PF15904.5 ORY36706.1 - 5.5 7.4 8.0 20 5.6 0.7 2.8 2 1 0 3 3 3 0 LKB1 serine/threonine kinase interacting protein 1 DUF4479 PF14794.6 ORY36706.1 - 7.4 6.5 13.3 7.2 6.5 0.2 4.7 6 0 0 6 6 5 0 Domain of unknown function (DUF4479) BRO1 PF03097.18 ORY36707.1 - 1.4e-65 221.6 7.8 3.5e-65 220.3 6.6 2.1 2 1 0 2 2 2 1 BRO1-like domain PP_M1 PF03012.14 ORY36709.1 - 3 7.3 5.7 4.3 6.8 5.7 1.1 1 0 0 1 1 1 0 Phosphoprotein HTH_45 PF14947.6 ORY36710.1 - 0.13 12.3 0.2 0.27 11.2 0.2 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix CtsR_C PF17727.1 ORY36710.1 - 0.2 11.8 0.0 0.37 11.0 0.0 1.3 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain zf-C2HE PF16278.5 ORY36711.1 - 1.4e-17 63.9 1.1 4.3e-17 62.3 0.1 2.2 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 ORY36711.1 - 4.6e-16 59.3 3.6 1.6e-14 54.4 1.5 2.5 2 1 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 ORY36711.1 - 1.9e-10 41.3 3.3 3.3e-08 34.2 3.3 2.4 1 1 0 1 1 1 1 HIT domain zf-C2H2 PF00096.26 ORY36711.1 - 0.014 15.8 0.7 0.047 14.2 0.7 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type Bystin PF05291.11 ORY36711.1 - 0.031 13.6 0.3 0.047 13.0 0.3 1.2 1 0 0 1 1 1 0 Bystin zf-C2H2_4 PF13894.6 ORY36711.1 - 0.044 14.6 0.5 0.15 13.0 0.5 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger CRAL_TRIO PF00650.20 ORY36711.1 - 0.069 12.9 0.0 0.1 12.3 0.0 1.5 1 1 0 1 1 1 0 CRAL/TRIO domain F-box-like PF12937.7 ORY36712.1 - 9.9e-05 22.2 0.1 0.00016 21.5 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY36712.1 - 0.0042 16.9 0.1 0.013 15.4 0.1 1.7 2 0 0 2 2 2 1 F-box domain Ank_2 PF12796.7 ORY36713.1 - 0.035 14.7 0.1 0.086 13.4 0.1 1.8 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 ORY36714.1 - 0.0068 17.0 0.0 0.013 16.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY36714.1 - 0.025 15.0 0.0 0.08 13.4 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 ORY36714.1 - 0.073 13.7 0.0 0.2 12.3 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat Ank_2 PF12796.7 ORY36715.1 - 7.6e-09 36.0 0.0 0.00026 21.5 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY36715.1 - 6.1e-08 32.3 0.1 0.89 10.3 0.0 4.0 3 1 1 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 ORY36715.1 - 1.5e-06 28.4 0.1 1 9.7 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY36715.1 - 7.2e-06 26.4 0.1 0.19 12.4 0.0 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY36715.1 - 0.078 13.5 0.0 13 6.4 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeat Hydrolase_6 PF13344.6 ORY36716.1 - 3.6e-20 72.0 0.0 1.1e-19 70.4 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY36716.1 - 8.8e-17 60.9 0.0 1.8e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 ORY36716.1 - 0.00011 22.6 0.0 0.00017 21.9 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY36716.1 - 0.00024 21.3 0.0 0.0034 17.5 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Spindle_Spc25 PF08234.12 ORY36716.1 - 0.14 12.4 0.0 0.69 10.2 0.0 2.0 2 1 1 3 3 3 0 Chromosome segregation protein Spc25 Hydrolase_6 PF13344.6 ORY36717.1 - 2.8e-27 94.8 0.0 7.8e-27 93.3 0.0 1.8 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY36717.1 - 1.2e-17 63.7 0.0 4e-17 62.0 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 ORY36717.1 - 6.1e-07 29.7 0.0 0.00015 21.9 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY36717.1 - 2.4e-06 28.0 0.0 4.4e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DSPn PF14671.6 ORY36718.1 - 3.2e-30 105.4 0.1 9.5e-29 100.7 0.1 2.8 2 1 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 ORY36718.1 - 8.6e-14 51.5 0.0 2.2e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY36718.1 - 0.00047 19.8 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 ORY36718.1 - 0.049 13.6 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family TPR_8 PF13181.6 ORY36719.1 - 0.029 14.6 2.0 0.9 9.9 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY36719.1 - 0.034 14.2 7.6 0.79 10.0 0.3 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY36719.1 - 0.21 12.5 0.9 1.8 9.6 0.9 2.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY36719.1 - 0.81 10.0 4.6 4.8 7.5 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat CENP-B_dimeris PF09026.10 ORY36720.1 - 0.037 14.4 6.3 0.071 13.5 6.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 ORY36720.1 - 0.39 10.0 4.8 0.57 9.5 4.8 1.3 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 ORY36720.1 - 6.1 6.5 14.0 0.94 9.2 9.3 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein OB_NTP_bind PF07717.16 ORY36721.1 - 5.1e-11 42.8 0.0 1.7e-10 41.1 0.0 1.9 1 1 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 ORY36721.1 - 4.8e-07 30.0 0.3 1.3e-06 28.7 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ORY36721.1 - 2.3e-06 27.9 0.0 1.1e-05 25.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 ORY36721.1 - 3.4e-05 24.1 0.0 0.00011 22.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 ORY36721.1 - 3.7e-05 23.6 0.0 0.00015 21.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 ORY36721.1 - 0.0097 15.6 0.1 0.023 14.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY36721.1 - 0.076 13.3 0.1 0.32 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 ORY36722.1 - 2.4e-06 28.2 0.1 8 7.5 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat FGE-sulfatase PF03781.16 ORY36723.1 - 1.3e-20 74.1 1.3 5.1e-10 39.4 0.2 2.2 1 1 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 ORY36723.1 - 0.0041 17.6 0.0 0.0089 16.5 0.0 1.5 1 0 0 1 1 1 1 DinB superfamily MIR PF02815.19 ORY36724.1 - 3.4e-05 23.8 0.0 0.012 15.5 0.0 2.0 1 1 1 2 2 2 2 MIR domain SH3_9 PF14604.6 ORY36726.1 - 2.7e-16 59.1 0.0 3.3e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 ORY36726.1 - 1e-14 53.9 0.0 5.9e-06 25.8 0.0 2.5 2 0 0 2 2 2 2 SH3 domain Phage_HK97_TLTM PF06120.11 ORY36726.1 - 0.00094 18.4 0.9 0.0017 17.6 0.9 1.3 1 0 0 1 1 1 1 Tail length tape measure protein SH3_2 PF07653.17 ORY36726.1 - 0.00094 18.8 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain DUF4366 PF14283.6 ORY36726.1 - 0.096 12.7 0.0 0.37 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) HsbA PF12296.8 ORY36727.1 - 0.015 15.7 1.7 0.025 15.0 1.5 1.6 1 1 0 1 1 1 0 Hydrophobic surface binding protein A Fez1 PF06818.15 ORY36727.1 - 0.037 14.5 6.8 0.86 10.0 1.0 2.1 1 1 1 2 2 2 0 Fez1 DUF4634 PF15465.6 ORY36727.1 - 0.043 14.1 0.4 0.3 11.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4634) NYD-SP28_assoc PF14775.6 ORY36727.1 - 0.088 12.9 0.8 0.21 11.7 0.8 1.6 1 0 0 1 1 1 0 Sperm tail C-terminal domain CRR7 PF12095.8 ORY36727.1 - 0.23 11.9 3.7 0.62 10.6 0.8 2.6 1 1 2 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 DUF4201 PF13870.6 ORY36727.1 - 1.1 9.0 7.7 0.79 9.4 0.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Lebercilin PF15619.6 ORY36727.1 - 1.2 8.7 8.7 1 9.0 0.3 2.6 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease TACC_C PF05010.14 ORY36728.1 - 0.013 15.3 5.9 0.066 13.0 1.6 2.3 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal TetR_C_13 PF16925.5 ORY36728.1 - 0.06 13.3 0.9 0.81 9.6 0.1 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Myc-LZ PF02344.15 ORY36728.1 - 0.13 12.3 2.7 5.9 7.1 0.1 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain DUF1664 PF07889.12 ORY36728.1 - 1 9.4 6.1 0.7 9.9 0.8 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.8 ORY36728.1 - 3.1 8.1 10.8 0.24 11.6 4.0 2.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4470 PF14737.6 ORY36729.1 - 0.12 12.6 0.2 0.45 10.7 0.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4470) T4-gp15_tss PF16724.5 ORY36730.1 - 0.096 12.4 0.4 0.31 10.8 0.3 1.8 2 0 0 2 2 2 0 T4-like virus Myoviridae tail sheath stabiliser DUF745 PF05335.13 ORY36730.1 - 5.6 6.6 6.2 56 3.4 1.4 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF745) Baculo_PEP_C PF04513.12 ORY36730.1 - 8.5 6.4 9.6 1.1 9.3 0.1 3.3 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2207 PF09972.9 ORY36731.1 - 0.11 11.3 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM100 PF16311.5 ORY36731.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 100 SCIMP PF15050.6 ORY36731.1 - 0.21 12.1 3.1 6.3 7.3 0.9 2.2 1 1 1 2 2 2 0 SCIMP protein RtcB PF01139.17 ORY36732.1 - 1.6e-54 185.7 0.0 6.8e-45 154.0 0.0 2.1 2 0 0 2 2 2 2 tRNA-splicing ligase RtcB SWIRM-assoc_3 PF16498.5 ORY36732.1 - 0.11 12.7 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal Ank_2 PF12796.7 ORY36733.1 - 0.00012 22.6 0.0 0.06 13.9 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORY36733.1 - 0.2 12.2 1.5 16 6.1 0.1 4.0 4 0 0 4 4 4 0 Ankyrin repeat Ank_2 PF12796.7 ORY36734.1 - 2.4e-15 56.9 1.9 1.3e-08 35.3 0.2 3.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY36734.1 - 1.7e-07 31.0 4.0 0.0034 17.7 0.0 6.1 6 1 1 7 7 7 1 Ankyrin repeat Ank_4 PF13637.6 ORY36734.1 - 7.1e-06 26.5 4.2 0.15 12.7 0.1 5.1 3 1 4 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY36734.1 - 3.6e-05 23.9 2.1 1.5 9.2 0.1 4.6 1 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY36734.1 - 0.24 11.9 8.9 5.7 7.6 0.1 4.3 5 1 0 5 5 5 0 Ankyrin repeat Pam17 PF08566.10 ORY36736.1 - 1.2e-23 83.7 0.6 1.6e-23 83.3 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Y_phosphatase PF00102.27 ORY36737.1 - 1.8e-06 27.7 0.0 2.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 ORY36737.1 - 1e-05 25.7 0.0 1.7e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 ORY36737.1 - 1e-05 25.3 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 ORY36737.1 - 0.0014 18.8 0.0 0.0022 18.1 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate PTEN_C2 PF10409.9 ORY36737.1 - 0.016 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 C2 domain of PTEN tumour-suppressor protein Pam17 PF08566.10 ORY36738.1 - 1.4e-35 122.6 0.2 1.5e-35 122.5 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF2062 PF09835.9 ORY36738.1 - 0.051 13.4 0.9 0.075 12.9 0.9 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) AA_permease_2 PF13520.6 ORY36739.1 - 2.2e-25 89.4 45.0 2.8e-25 89.1 45.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY36739.1 - 4.6e-14 51.9 38.7 9.2e-14 50.9 38.7 1.4 1 1 0 1 1 1 1 Amino acid permease LPMO_10 PF03067.15 ORY36741.1 - 0.061 14.0 0.4 0.13 12.9 0.4 1.6 1 0 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading PriC PF07445.12 ORY36742.1 - 0.0041 17.1 22.6 0.017 15.1 7.7 2.5 2 1 0 2 2 2 2 Primosomal replication protein priC DUF5320 PF17253.2 ORY36742.1 - 1.6 9.8 13.6 3.4 8.8 0.3 3.8 2 2 2 4 4 4 0 Family of unknown function (DUF5320) DUF4391 PF14335.6 ORY36742.1 - 3.6 7.2 14.8 0.3 10.8 0.6 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4391) FAD_binding_4 PF01565.23 ORY36743.1 - 4.9e-19 68.4 0.1 8.8e-19 67.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 ORY36743.1 - 5.1e-10 39.3 2.5 5.1e-10 39.3 2.5 2.1 2 0 0 2 2 2 1 Berberine and berberine like V_ATPase_I PF01496.19 ORY36744.1 - 0.0029 15.6 6.1 0.0036 15.3 6.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family APG5 PF04106.12 ORY36744.1 - 0.016 14.8 0.2 0.021 14.4 0.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg5 T3SSipB PF16535.5 ORY36744.1 - 0.03 14.8 8.8 0.062 13.8 8.8 1.5 1 1 0 1 1 1 0 Type III cell invasion protein SipB GNVR PF13807.6 ORY36744.1 - 1.2 9.1 3.1 0.65 10.0 0.8 1.7 2 0 0 2 2 2 0 G-rich domain on putative tyrosine kinase FlaC_arch PF05377.11 ORY36744.1 - 1.3 9.5 3.7 1.2 9.5 0.5 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 ORY36744.1 - 8.3 6.3 6.9 1.9 8.3 2.2 2.0 1 1 1 2 2 2 0 Septum formation initiator DUF1126 PF06565.12 ORY36745.1 - 5.6e-101 331.5 5.8 1.7e-35 121.0 0.3 3.2 3 0 0 3 3 3 3 DUF1126 PH-like domain DUF5041 PF16444.5 ORY36745.1 - 0.032 14.5 0.0 1.6 9.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5041) CH PF00307.31 ORY36746.1 - 8.9e-17 61.2 0.0 1.1e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 ORY36746.1 - 0.0086 16.3 0.1 0.013 15.8 0.1 1.2 1 0 0 1 1 1 1 CDC24 Calponin MBOAT_2 PF13813.6 ORY36748.1 - 4.9e-10 39.5 0.2 1.4e-09 38.1 0.2 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MBOAT PF03062.19 ORY36748.1 - 0.022 14.1 5.9 0.11 11.8 4.5 2.5 1 1 0 1 1 1 0 MBOAT, membrane-bound O-acyltransferase family Peptidase_M13_N PF05649.13 ORY36749.1 - 2.6e-58 198.6 0.9 1.3e-57 196.2 0.9 1.9 1 1 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 ORY36749.1 - 4.3e-40 137.5 0.7 6e-33 114.2 0.0 2.5 2 0 0 2 2 2 2 Peptidase family M13 PP-binding PF00550.25 ORY36749.1 - 0.032 14.6 0.0 0.097 13.0 0.0 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site DUF1542 PF07564.11 ORY36749.1 - 0.085 13.0 0.3 0.085 13.0 0.3 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) DUF445 PF04286.12 ORY36749.1 - 0.19 11.5 1.2 0.37 10.6 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF445) CHAP PF05257.16 ORY36750.1 - 2.1e-11 44.2 0.0 3.2e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 CHAP domain UMPH-1 PF05822.12 ORY36751.1 - 2.6e-82 276.0 0.2 3.1e-82 275.8 0.2 1.0 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 ORY36751.1 - 1.9e-07 31.6 0.0 3.1e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SIR2 PF02146.17 ORY36751.1 - 0.15 12.0 0.1 0.49 10.3 0.1 1.8 2 0 0 2 2 2 0 Sir2 family Mid2 PF04478.12 ORY36752.1 - 0.00079 19.3 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Spc7 PF08317.11 ORY36753.1 - 0.053 12.4 19.1 0.076 11.9 5.2 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2218 PF09981.9 ORY36753.1 - 0.054 13.9 2.4 0.25 11.7 1.7 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2218) Cep57_CLD_2 PF14197.6 ORY36753.1 - 2.5 8.3 23.6 0.16 12.0 3.2 3.4 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 DUF1664 PF07889.12 ORY36753.1 - 3.2 7.8 9.2 1.7 8.7 0.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Rootletin PF15035.6 ORY36753.1 - 4.8 7.2 16.8 6.1 6.8 3.1 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion FlxA PF14282.6 ORY36753.1 - 6.3 6.8 16.8 2.4 8.2 7.0 3.3 3 0 0 3 3 3 0 FlxA-like protein DivIC PF04977.15 ORY36753.1 - 6.6 6.6 20.4 1.9 8.3 2.5 3.9 2 1 1 3 3 3 0 Septum formation initiator SAM_1 PF00536.30 ORY36754.1 - 0.0072 16.7 0.1 0.016 15.7 0.1 1.6 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 ORY36754.1 - 0.0084 16.1 0.1 0.013 15.5 0.1 1.2 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain DUF3450 PF11932.8 ORY36755.1 - 0.00077 18.8 1.2 0.001 18.4 1.0 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) Nsp1_C PF05064.13 ORY36755.1 - 0.00095 19.0 1.0 0.0011 18.8 1.0 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region ZapB PF06005.12 ORY36755.1 - 0.0011 19.4 4.4 0.0014 19.0 4.4 1.3 1 1 0 1 1 1 1 Cell division protein ZapB BLOC1_2 PF10046.9 ORY36755.1 - 0.0022 18.2 0.8 0.0029 17.9 0.8 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 ORY36755.1 - 0.0029 17.5 0.9 0.0033 17.3 0.9 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 BST2 PF16716.5 ORY36755.1 - 0.0042 17.6 2.2 0.0053 17.3 2.2 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 GAS PF13851.6 ORY36755.1 - 0.0057 16.0 2.8 0.0064 15.9 2.8 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding YabA PF06156.13 ORY36755.1 - 0.018 15.6 1.2 0.022 15.4 1.2 1.2 1 0 0 1 1 1 0 Initiation control protein YabA CCDC92 PF14916.6 ORY36755.1 - 0.019 14.7 3.5 0.034 13.9 3.3 1.6 1 1 0 1 1 1 0 Coiled-coil domain of unknown function Cluap1 PF10234.9 ORY36755.1 - 0.019 14.4 1.4 0.02 14.3 1.4 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Herpes_UL6 PF01763.16 ORY36755.1 - 0.019 13.5 1.5 0.02 13.5 1.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like HlyD_D23 PF16576.5 ORY36755.1 - 0.027 13.7 1.0 0.029 13.6 1.0 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion TMF_DNA_bd PF12329.8 ORY36755.1 - 0.034 14.1 1.1 0.034 14.1 1.1 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Rab_bind PF16704.5 ORY36755.1 - 0.034 14.2 0.3 2.8 8.1 0.1 2.3 1 1 1 2 2 2 0 Rab binding domain Sec34 PF04136.15 ORY36755.1 - 0.035 14.0 1.3 0.039 13.8 1.3 1.1 1 0 0 1 1 1 0 Sec34-like family APG6_N PF17675.1 ORY36755.1 - 0.046 14.3 2.7 0.062 13.8 2.7 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF948 PF06103.11 ORY36755.1 - 0.077 13.3 0.4 0.11 12.8 0.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 ORY36755.1 - 0.13 12.5 2.9 0.52 10.5 2.8 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 ORY36755.1 - 0.14 12.4 1.7 0.27 11.5 1.7 1.5 1 0 0 1 1 1 0 Haemolysin XhlA USP8_interact PF08941.10 ORY36755.1 - 0.15 11.9 1.9 0.18 11.6 1.9 1.1 1 0 0 1 1 1 0 USP8 interacting SlyX PF04102.12 ORY36755.1 - 0.27 11.9 4.6 2.1 9.0 4.6 2.1 1 1 0 1 1 1 0 SlyX DivIC PF04977.15 ORY36755.1 - 0.77 9.6 4.7 3.7 7.4 4.7 2.0 1 1 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 ORY36755.1 - 0.98 9.6 3.9 3.9 7.6 1.2 2.3 1 1 1 2 2 2 0 Basic region leucine zipper GPP34 PF05719.11 ORY36758.1 - 0.081 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) S1-P1_nuclease PF02265.16 ORY36804.1 - 4.8e-36 124.9 0.0 7.4e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 S1/P1 Nuclease Lipase_3 PF01764.25 ORY36805.1 - 1.6e-34 118.8 0.0 2.4e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORY36805.1 - 0.01 16.5 1.9 0.021 15.5 1.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 ORY36805.1 - 0.017 14.6 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Esterase PF00756.20 ORY36805.1 - 0.071 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Mucin PF01456.17 ORY36806.1 - 1.8 8.5 3.8 5.6 7.0 1.0 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF4982 PF16355.5 ORY36807.1 - 0.0085 16.0 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) DHHC PF01529.20 ORY36808.1 - 3.5 7.7 15.6 1.1 9.4 2.1 3.5 4 0 0 4 4 4 0 DHHC palmitoyltransferase DUF4282 PF14110.6 ORY36808.1 - 8.9 7.1 23.8 1.3 9.9 0.1 4.0 4 1 0 4 4 4 0 Domain of unknown function (DUF4282) Tetraspanin PF00335.20 ORY36808.1 - 9.4 5.9 23.6 0.1 12.3 11.5 3.2 3 2 0 3 3 3 0 Tetraspanin family hDGE_amylase PF14701.6 ORY36809.1 - 4.3e-153 510.5 0.3 4.4e-80 269.9 0.0 2.2 1 1 1 2 2 2 2 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 ORY36809.1 - 2.5e-108 362.4 0.0 4e-108 361.8 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 ORY36809.1 - 2.4e-60 204.3 0.0 3.4e-59 200.6 0.0 2.3 1 1 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 ORY36809.1 - 9.9e-10 38.4 0.0 2.3e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme MMM1 PF10296.9 ORY36810.1 - 0.0021 17.2 0.1 0.011 14.8 0.0 2.0 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 PH PF00169.29 ORY36810.1 - 0.012 16.1 0.0 0.023 15.2 0.0 1.5 1 0 0 1 1 1 0 PH domain cNMP_binding PF00027.29 ORY36812.1 - 3.4e-16 59.1 0.0 9.6e-16 57.6 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Mito_carr PF00153.27 ORY36813.1 - 7.9e-24 83.4 2.8 2.5e-12 46.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein VanW PF04294.13 ORY36813.1 - 0.024 14.3 0.1 0.038 13.7 0.1 1.3 1 0 0 1 1 1 0 VanW like protein DUF726 PF05277.12 ORY36814.1 - 7.8e-63 212.5 0.1 2.4e-62 210.8 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 ORY36814.1 - 0.016 15.3 0.0 0.032 14.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain PE-PPE PF08237.11 ORY36814.1 - 0.1 12.1 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 PE-PPE domain DUF866 PF05907.13 ORY36815.1 - 4.5e-48 163.1 0.1 7.5e-48 162.4 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) DUF604 PF04646.12 ORY36815.1 - 6.7e-11 42.1 0.3 1.8e-10 40.7 0.3 1.7 2 1 0 2 2 2 1 Protein of unknown function, DUF604 Fringe PF02434.16 ORY36815.1 - 8.3e-09 35.2 0.2 6.2e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 Fringe-like PAN_4 PF14295.6 ORY36815.1 - 0.0051 16.7 0.4 0.013 15.4 0.4 1.6 1 0 0 1 1 1 1 PAN domain Galactosyl_T PF01762.21 ORY36815.1 - 0.21 11.4 0.0 0.44 10.3 0.0 1.4 1 0 0 1 1 1 0 Galactosyltransferase TPR_21 PF09976.9 ORY36816.1 - 0.039 13.6 0.2 0.047 13.4 0.2 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain Lysozyme_like PF13702.6 ORY36816.1 - 0.064 13.0 0.1 0.071 12.8 0.1 1.2 1 0 0 1 1 1 0 Lysozyme-like Sel_put PF04328.13 ORY36816.1 - 0.16 12.0 0.1 0.16 12.0 0.1 1.9 2 0 0 2 2 2 0 Selenoprotein, putative MMM1 PF10296.9 ORY36818.1 - 0.032 13.3 0.0 0.032 13.3 0.0 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Lactamase_B_6 PF16661.5 ORY36819.1 - 4.7e-16 58.8 0.0 8.4e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 ORY36819.1 - 1.7e-06 27.5 0.0 3.6e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Putative beta-lactamase-like family cNMP_binding PF00027.29 ORY36820.1 - 8.5e-09 35.4 0.0 5.1e-08 32.9 0.0 2.2 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain InvH PF04741.12 ORY36820.1 - 0.1 12.5 2.8 0.11 12.4 0.0 2.4 3 0 0 3 3 3 0 InvH outer membrane lipoprotein F-box PF00646.33 ORY36821.1 - 5.5e-05 22.9 0.5 0.00022 21.0 0.3 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY36821.1 - 0.003 17.4 0.7 0.02 14.8 0.3 2.3 2 0 0 2 2 2 1 F-box-like DUF2263 PF10021.9 ORY36822.1 - 1.2e-07 32.2 4.1 1.7e-07 31.7 0.0 3.5 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2263) Pim PF16765.5 ORY36822.1 - 0.033 14.4 0.1 0.094 12.9 0.1 1.7 1 0 0 1 1 1 0 Pesticin immunity protein Rep_N PF08724.10 ORY36822.1 - 0.033 13.9 0.1 0.47 10.2 0.0 2.5 2 0 0 2 2 2 0 Rep protein catalytic domain like WD40 PF00400.32 ORY36823.1 - 2.3e-09 37.7 3.0 0.0035 18.1 0.0 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY36823.1 - 2.8e-07 30.7 0.1 0.015 15.6 0.0 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 ORY36823.1 - 0.032 14.2 0.1 6.9 6.7 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat TPR_2 PF07719.17 ORY36824.1 - 9.5e-07 28.5 0.0 0.014 15.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY36824.1 - 1.7e-06 27.6 0.0 0.069 13.0 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY36824.1 - 7.3e-05 23.3 0.0 0.0016 19.0 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY36824.1 - 0.00022 21.8 0.2 0.44 11.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY36824.1 - 0.00045 19.9 0.0 0.023 14.4 0.0 2.5 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.6 ORY36824.1 - 0.00069 19.9 0.3 0.81 10.0 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY36824.1 - 0.0031 17.6 0.0 2 8.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY36824.1 - 0.0091 16.5 0.0 0.26 11.8 0.0 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 ORY36824.1 - 0.0099 16.3 0.2 3.3 8.2 0.0 2.3 2 0 0 2 2 2 2 Bacterial transcriptional activator domain ANAPC3 PF12895.7 ORY36824.1 - 0.035 14.3 0.1 12 6.2 0.0 2.3 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Hexokinase_2 PF03727.16 ORY36825.1 - 4e-81 272.0 0.0 6.6e-81 271.3 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORY36825.1 - 3.3e-70 236.1 0.0 4.5e-70 235.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Sel1 PF08238.12 ORY36828.1 - 2.6e-17 62.9 20.3 0.0038 17.9 0.1 7.4 9 0 0 9 9 9 5 Sel1 repeat TPR_16 PF13432.6 ORY36828.1 - 0.01 16.4 1.7 0.036 14.7 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Ferritin-like PF12902.7 ORY36829.1 - 0.081 12.8 0.4 0.11 12.3 0.3 1.3 1 1 0 1 1 1 0 Ferritin-like DNA_pol_phi PF04931.13 ORY36829.1 - 0.1 10.7 8.1 0.12 10.5 8.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Cwf_Cwc_15 PF04889.12 ORY36829.1 - 0.15 11.8 7.9 0.19 11.4 7.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.6 ORY36829.1 - 0.23 11.9 6.5 0.34 11.3 6.5 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1754 PF08555.10 ORY36829.1 - 0.45 11.4 7.9 0.7 10.7 7.9 1.4 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) RRN3 PF05327.11 ORY36829.1 - 0.45 9.0 2.7 0.51 8.8 2.7 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RXT2_N PF08595.11 ORY36829.1 - 0.63 10.0 5.2 1.1 9.3 5.2 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 ORY36829.1 - 0.71 10.3 9.7 1.1 9.7 9.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 ORY36829.1 - 4.5 6.9 5.9 5.9 6.5 5.9 1.4 1 1 0 1 1 1 0 FAM176 family 7tm_3 PF00003.22 ORY36830.1 - 9.9e-31 107.3 26.6 1.6e-30 106.6 26.6 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR FLgD_tudor PF13861.6 ORY36830.1 - 0.03 14.6 0.0 2.6 8.3 0.0 3.8 2 1 0 2 2 2 0 FlgD Tudor-like domain COX4 PF02936.14 ORY36830.1 - 0.39 10.7 1.0 5.1 7.1 0.2 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase subunit IV GTP_EFTU PF00009.27 ORY36831.1 - 1.5e-16 60.6 0.0 2.6e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY36831.1 - 0.0066 16.4 0.1 4 7.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ABC_tran PF00005.27 ORY36831.1 - 0.0069 16.9 0.0 0.019 15.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter PduV-EutP PF10662.9 ORY36831.1 - 0.007 16.1 0.3 19 5.0 0.0 4.0 3 1 1 4 4 4 1 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 ORY36831.1 - 0.029 13.8 0.6 7.4 6.0 0.0 2.8 2 1 0 2 2 2 0 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY36831.1 - 0.032 14.3 0.1 0.1 12.7 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase DHO_dh PF01180.21 ORY36832.1 - 1.7e-60 204.7 0.1 3.5e-60 203.7 0.1 1.5 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase NUFIP1 PF10453.9 ORY36833.1 - 0.18 11.7 0.1 0.41 10.5 0.1 1.5 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Iso_dh PF00180.20 ORY36834.1 - 5.3e-91 305.4 0.0 6.6e-91 305.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Peptidase_C78 PF07910.13 ORY36835.1 - 6.7e-25 87.8 0.5 3.5e-24 85.5 0.5 2.1 1 1 0 1 1 1 1 Peptidase family C78 EF-hand_4 PF12763.7 ORY36836.1 - 4.6e-20 71.5 0.0 6.5e-09 35.7 0.0 3.9 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_6 PF13405.6 ORY36836.1 - 0.00032 20.4 0.0 0.19 11.7 0.0 3.7 2 1 1 3 3 3 1 EF-hand domain UBA PF00627.31 ORY36836.1 - 0.0011 18.8 0.0 0.0031 17.4 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.32 ORY36836.1 - 0.015 14.8 0.0 3.9 7.3 0.0 4.2 5 0 0 5 5 5 0 EF hand Spc7 PF08317.11 ORY36836.1 - 3.3 6.5 32.8 0.069 12.0 14.7 2.4 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF2213 PF09979.9 ORY36839.1 - 0.033 14.2 0.2 0.042 13.8 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2213) DUF4293 PF14126.6 ORY36839.1 - 0.068 13.4 0.1 0.088 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) N1221 PF07923.13 ORY36841.1 - 0.025 13.8 0.1 0.028 13.6 0.1 1.1 1 0 0 1 1 1 0 N1221-like protein DUF3402 PF11882.8 ORY36842.1 - 1.2e-35 123.5 3.6 1.1e-19 70.9 0.6 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) PH_RBD PF12068.8 ORY36844.1 - 0.13 11.7 1.2 0.2 11.1 0.4 1.8 2 0 0 2 2 2 0 Rab-binding domain (RBD) Caprin-1_C PF12287.8 ORY36844.1 - 2 8.5 15.1 0.051 13.7 2.8 2.1 1 1 1 2 2 2 0 Cytoplasmic activation/proliferation-associated protein-1 C term UCH PF00443.29 ORY36846.1 - 9.4e-59 199.0 0.0 1.3e-58 198.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY36846.1 - 1.5e-11 44.5 0.0 8.2e-11 42.1 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Smr PF01713.21 ORY36847.1 - 7.5e-10 39.0 0.0 1.8e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Smr domain CUE PF02845.16 ORY36847.1 - 4.2e-07 29.5 0.1 0.00096 18.8 0.0 2.7 2 0 0 2 2 2 2 CUE domain DMA PF03474.14 ORY36847.1 - 3.3e-06 26.6 0.0 0.00028 20.4 0.0 2.3 2 0 0 2 2 2 1 DMRTA motif DUF1771 PF08590.10 ORY36847.1 - 7.6e-05 23.0 0.1 0.00017 21.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) HTH_8 PF02954.19 ORY36847.1 - 0.038 13.8 0.0 0.2 11.5 0.0 2.2 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family G-alpha PF00503.20 ORY36848.1 - 1.9e-111 372.7 4.3 2.3e-111 372.4 4.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY36848.1 - 5.4e-17 61.8 0.5 6.9e-13 48.4 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 ORY36848.1 - 1.6e-05 25.1 0.6 0.024 14.9 0.1 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORY36848.1 - 0.0023 17.5 1.1 0.16 11.5 0.2 2.4 2 0 0 2 2 2 1 Ras family FtsK_SpoIIIE PF01580.18 ORY36848.1 - 0.004 16.5 0.0 0.0081 15.5 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Gtr1_RagA PF04670.12 ORY36848.1 - 0.01 15.2 5.1 0.039 13.3 0.3 2.7 2 2 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 ORY36848.1 - 0.041 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY36848.1 - 0.054 13.6 0.1 11 6.1 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 ORY36848.1 - 0.17 11.7 2.3 0.37 10.5 0.2 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 ORY36848.1 - 0.18 11.3 1.9 2.4 7.7 0.1 2.9 1 1 2 3 3 3 0 Elongation factor Tu GTP binding domain G-alpha PF00503.20 ORY36850.1 - 3e-75 253.6 4.2 1.7e-44 152.4 2.3 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Nab1 PF04902.12 ORY36850.1 - 0.0051 17.2 0.1 0.0092 16.4 0.1 1.4 1 0 0 1 1 1 1 Conserved region in Nab1 PROCN PF08083.11 ORY36850.1 - 0.047 12.4 0.0 0.073 11.8 0.0 1.2 1 0 0 1 1 1 0 PROCN (NUC071) domain G-alpha PF00503.20 ORY36851.1 - 1.5e-107 359.9 3.5 1.7e-107 359.7 3.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY36851.1 - 5.3e-16 58.6 1.0 1.3e-11 44.2 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY36851.1 - 2e-07 30.6 1.8 4.2e-05 23.0 0.2 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY36851.1 - 2.7e-07 30.8 0.5 0.00084 19.5 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORY36851.1 - 0.0009 18.9 0.3 0.07 12.7 0.1 2.3 2 0 0 2 2 2 1 Ras family AAA_29 PF13555.6 ORY36851.1 - 0.0068 16.1 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.27 ORY36851.1 - 0.099 12.2 0.8 1.9 8.0 0.1 2.9 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain G-alpha PF00503.20 ORY36852.1 - 1.9e-95 320.0 3.3 3.3e-95 319.2 3.3 1.4 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY36852.1 - 9e-16 57.8 0.2 5.8e-12 45.4 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 ORY36852.1 - 2.5e-05 24.5 0.1 0.03 14.5 0.0 2.8 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 ORY36852.1 - 0.0013 18.1 3.4 0.027 13.8 0.3 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 ORY36852.1 - 0.055 13.2 0.6 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_27 PF13514.6 ORY36852.1 - 0.071 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 ORY36852.1 - 0.073 12.6 0.2 0.7 9.4 0.3 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain SNF5 PF04855.12 ORY36853.1 - 8.1e-49 166.5 0.1 1.2e-48 166.0 0.1 1.2 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 ORY36853.1 - 2.3e-10 39.9 0.6 5.6e-10 38.6 0.6 1.7 1 0 0 1 1 1 1 GATA zinc finger Adenylsucc_synt PF00709.21 ORY36854.1 - 1.9e-174 580.5 0.0 2.1e-174 580.3 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Chitin_synth_2 PF03142.15 ORY36855.1 - 1.2e-213 710.6 0.1 1.8e-213 710.0 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 ORY36855.1 - 3.9e-101 339.4 0.0 1.1e-63 215.6 0.1 2.5 1 1 1 2 2 2 2 Myosin head (motor domain) Glyco_trans_2_3 PF13632.6 ORY36855.1 - 1.2e-14 54.6 0.7 3.5e-14 53.2 0.7 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 DEK_C PF08766.11 ORY36855.1 - 4.3e-13 49.0 0.0 2.2e-12 46.7 0.0 2.2 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 ORY36855.1 - 1.3e-11 44.9 0.0 5.7e-10 39.5 0.0 2.9 4 0 0 4 4 4 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.28 ORY36855.1 - 3.8e-09 36.6 0.5 0.00044 20.3 0.0 2.9 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 ORY36855.1 - 0.0001 22.2 0.0 0.48 10.2 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 AAA_33 PF13671.6 ORY36855.1 - 0.0025 18.0 0.0 0.0054 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY36855.1 - 0.017 15.4 0.0 0.046 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Glyco_transf_21 PF13506.6 ORY36855.1 - 0.021 14.3 0.0 0.057 12.9 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 21 AAA_16 PF13191.6 ORY36855.1 - 0.033 14.6 0.0 0.07 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 ORY36855.1 - 0.087 11.7 0.1 0.39 9.6 0.0 1.9 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain BPL_N PF09825.9 ORY36856.1 - 1.2e-76 258.3 0.0 1.5e-76 257.9 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 ORY36856.1 - 1.2e-22 80.2 0.0 2e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Glyco_hydro_42M PF08532.10 ORY36856.1 - 7.8e-05 22.3 0.0 0.00018 21.1 0.0 1.6 2 0 0 2 2 2 1 Beta-galactosidase trimerisation domain DJ-1_PfpI PF01965.24 ORY36856.1 - 0.013 15.3 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family GATase_3 PF07685.14 ORY36856.1 - 0.079 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain cNMP_binding PF00027.29 ORY36857.1 - 1.1e-40 137.5 0.3 4.5e-20 71.5 0.1 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain OHCU_decarbox PF09349.10 ORY36857.1 - 0.0012 19.4 0.5 0.17 12.4 0.1 2.4 2 0 0 2 2 2 1 OHCU decarboxylase Cupin_3 PF05899.12 ORY36857.1 - 0.028 14.1 0.2 0.21 11.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Glyco_hydro_38 PF18438.1 ORY36857.1 - 0.07 13.2 0.0 0.21 11.7 0.0 1.9 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal domain 1 YabA PF06156.13 ORY36857.1 - 0.09 13.4 2.6 0.32 11.7 0.3 2.2 2 0 0 2 2 2 0 Initiation control protein YabA DNA_gyraseB PF00204.25 ORY36857.1 - 1.8 8.0 6.9 6.5 6.2 0.0 3.4 3 1 0 3 3 3 0 DNA gyrase B LRR_6 PF13516.6 ORY36858.1 - 1.1e-11 43.8 12.6 0.009 16.0 0.0 7.1 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 ORY36858.1 - 1.1e-07 32.1 1.7 0.045 14.2 0.0 4.5 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY36858.1 - 0.22 12.2 12.3 18 6.4 0.0 5.9 4 2 0 4 4 4 0 Leucine Rich Repeat zf-rbx1 PF12678.7 ORY36859.1 - 4.4e-12 46.1 3.6 4.4e-12 46.1 2.1 1.8 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 ORY36859.1 - 1.1e-08 35.2 7.2 8.5e-08 32.4 7.2 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORY36859.1 - 3.8e-07 29.9 1.9 7.9e-07 28.8 1.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY36859.1 - 1.8e-06 27.8 0.2 4.3e-06 26.6 0.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 ORY36859.1 - 5.1e-06 26.4 0.2 1.4e-05 25.0 0.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 ORY36859.1 - 9.4e-06 25.4 2.1 9.4e-06 25.4 2.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY36859.1 - 2.6e-05 24.1 2.9 0.00013 21.8 3.3 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY36859.1 - 4.3e-05 23.3 2.5 0.0012 18.7 0.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 ORY36859.1 - 0.00017 21.1 0.6 0.00048 19.7 0.6 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 ORY36859.1 - 0.00065 19.5 3.1 0.0018 18.1 3.1 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-4CXXC_R1 PF10497.9 ORY36859.1 - 0.0016 18.7 0.1 0.0085 16.3 0.0 2.1 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_11 PF17123.5 ORY36859.1 - 0.0021 17.7 1.5 0.016 15.0 0.0 2.5 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 ORY36859.1 - 0.022 14.9 1.7 0.058 13.6 1.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 ORY36859.1 - 0.039 14.1 1.3 0.076 13.2 0.6 2.0 2 0 0 2 2 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 ORY36859.1 - 0.07 13.4 1.6 0.18 12.1 1.6 1.7 1 0 0 1 1 1 0 RING-like domain FliT PF05400.13 ORY36859.1 - 0.098 13.5 4.6 7.5 7.4 2.5 2.7 2 0 0 2 2 2 0 Flagellar protein FliT TFIIA PF03153.13 ORY36859.1 - 0.57 10.1 4.0 0.76 9.7 4.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_4 PF14570.6 ORY36859.1 - 0.75 9.6 3.8 0.84 9.5 1.4 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_9 PF13901.6 ORY36859.1 - 1.1 9.2 7.0 0.089 12.8 2.0 1.7 2 0 0 2 2 1 0 Putative zinc-RING and/or ribbon RINGv PF12906.7 ORY36859.1 - 2.6 8.3 6.0 0.75 10.0 2.0 2.0 2 0 0 2 2 2 0 RING-variant domain Sid-5 PF17204.3 ORY36859.1 - 4.6 7.5 7.5 12 6.2 1.6 2.6 1 1 1 2 2 2 0 Sid-5 family Ras PF00071.22 ORY36860.1 - 5e-43 146.5 0.1 5.9e-43 146.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY36860.1 - 2.3e-25 89.2 0.0 3.1e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY36860.1 - 1.2e-12 47.6 0.0 1.6e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY36860.1 - 1.5e-05 24.5 0.0 1.7e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORY36860.1 - 0.0016 18.0 0.0 0.0059 16.2 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 ORY36860.1 - 0.005 16.8 0.0 0.065 13.1 0.0 2.2 2 1 1 3 3 3 1 RsgA GTPase AAA_24 PF13479.6 ORY36860.1 - 0.062 13.0 0.1 0.62 9.8 0.0 1.9 1 1 0 2 2 2 0 AAA domain ArfGap PF01412.18 ORY36861.1 - 5.4e-39 132.9 0.0 1.2e-38 131.8 0.0 1.6 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf SUIM_assoc PF16619.5 ORY36861.1 - 0.058 13.5 0.6 0.058 13.5 0.6 3.7 3 1 1 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 ORY36861.1 - 0.16 12.0 23.9 0.26 11.3 23.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 ORY36861.1 - 0.16 11.6 25.5 0.11 12.1 10.3 2.3 2 0 0 2 2 2 0 Spt20 family ABC_transp_aux PF09822.9 ORY36862.1 - 5.1e-06 26.2 0.0 7.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DUF3581 PF12119.8 ORY36863.1 - 0.024 14.0 0.2 0.035 13.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3581) ThiF PF00899.21 ORY36865.1 - 1.6e-64 217.6 0.0 2.2e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 ORY36865.1 - 1e-19 70.5 0.7 2.8e-19 69.0 0.7 1.7 1 1 0 1 1 1 1 E2 binding domain Pyr_redox PF00070.27 ORY36865.1 - 0.02 15.4 0.0 0.041 14.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ORY36865.1 - 0.079 13.0 0.5 0.18 11.9 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase cNMP_binding PF00027.29 ORY36867.1 - 2.6e-09 37.0 0.0 3.2e-06 27.1 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain cNMP_binding PF00027.29 ORY36868.1 - 2e-23 82.3 0.1 1.4e-17 63.6 0.0 3.1 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain DUF220 PF02713.14 ORY36868.1 - 0.17 12.0 0.2 0.69 10.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF220 cNMP_binding PF00027.29 ORY36869.1 - 1.3e-19 70.0 0.0 4.2e-16 58.8 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 ORY36869.1 - 0.022 14.4 0.0 0.059 13.1 0.0 1.8 2 0 0 2 2 2 0 Cupin domain Filament PF00038.21 ORY36870.1 - 0.0002 21.1 6.0 0.0002 21.1 6.0 2.5 1 1 0 2 2 2 1 Intermediate filament protein Spc7 PF08317.11 ORY36870.1 - 0.00022 20.2 5.8 0.00022 20.2 5.8 3.2 3 0 0 3 3 3 1 Spc7 kinetochore protein LRRFIP PF09738.9 ORY36870.1 - 0.0023 17.5 9.7 0.0023 17.5 9.7 2.1 2 1 0 2 2 2 1 LRRFIP family Ax_dynein_light PF10211.9 ORY36870.1 - 0.005 16.8 2.6 0.005 16.8 2.6 3.2 2 1 1 3 3 3 1 Axonemal dynein light chain CCDC-167 PF15188.6 ORY36870.1 - 0.0099 16.2 9.4 0.029 14.7 2.4 2.9 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 167 DHR10 PF18595.1 ORY36870.1 - 0.017 15.2 5.7 0.017 15.2 5.7 3.8 5 0 0 5 5 3 0 Designed helical repeat protein 10 domain Tropomyosin_1 PF12718.7 ORY36870.1 - 0.076 13.2 16.8 0.038 14.1 4.7 3.4 3 0 0 3 3 3 0 Tropomyosin like SlyX PF04102.12 ORY36870.1 - 0.14 12.8 11.6 3.4 8.3 2.0 4.3 3 1 0 3 3 3 0 SlyX Leu_zip PF15294.6 ORY36870.1 - 0.63 9.5 15.4 1.6 8.2 4.2 2.3 2 0 0 2 2 2 0 Leucine zipper NPV_P10 PF05531.12 ORY36870.1 - 0.75 10.3 8.3 1.1 9.7 0.9 4.0 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein SOGA PF11365.8 ORY36870.1 - 0.85 10.8 12.2 6.4 8.0 1.9 3.0 2 1 0 2 2 2 0 Protein SOGA T3SSipB PF16535.5 ORY36870.1 - 1.1 9.8 11.1 0.063 13.7 3.1 2.5 1 1 1 2 2 2 0 Type III cell invasion protein SipB Tropomyosin PF00261.20 ORY36870.1 - 1.1 8.5 14.3 0.79 9.1 2.9 3.1 3 0 0 3 3 3 0 Tropomyosin LMBR1 PF04791.16 ORY36870.1 - 1.9 7.3 12.2 6.5 5.5 0.0 2.1 1 1 1 2 2 2 0 LMBR1-like membrane protein AIM3 PF17096.5 ORY36870.1 - 2 9.4 6.2 1.7 9.6 0.1 2.8 3 0 0 3 3 2 0 Altered inheritance of mitochondria protein 3 TolA_bind_tri PF16331.5 ORY36870.1 - 2.7 8.1 16.7 25 5.0 2.4 4.5 3 1 1 4 4 4 0 TolA binding protein trimerisation Cnn_1N PF07989.11 ORY36870.1 - 2.9 8.1 14.2 0.83 9.9 0.4 3.5 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 FapA PF03961.13 ORY36870.1 - 3.4 6.2 10.3 4.6 5.7 1.3 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF4164 PF13747.6 ORY36870.1 - 5.2 7.4 13.8 0.26 11.6 1.9 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) OmpH PF03938.14 ORY36870.1 - 7.5 6.9 18.2 1.6 9.0 0.2 3.2 2 1 2 4 4 4 0 Outer membrane protein (OmpH-like) Spc24 PF08286.11 ORY36870.1 - 7.5 6.8 18.9 9.8 6.5 4.2 4.0 4 1 0 4 4 4 0 Spc24 subunit of Ndc80 Fez1 PF06818.15 ORY36870.1 - 8.1 6.9 17.7 3.5 8.0 9.6 2.4 1 1 0 2 2 2 0 Fez1 Bap31_Bap29_C PF18035.1 ORY36870.1 - 8.5 6.5 11.2 5.9 7.0 0.0 3.9 4 1 0 4 4 4 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4407 PF14362.6 ORY36870.1 - 9.6 5.5 17.4 87 2.3 17.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ATG16 PF08614.11 ORY36870.1 - 9.9 6.3 34.5 0.86 9.8 5.6 4.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF2052 PF09747.9 ORY36871.1 - 6.6e-34 117.8 12.5 1e-33 117.2 12.5 1.2 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) DUF4090 PF13319.6 ORY36871.1 - 0.099 12.9 0.3 10 6.4 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4090) EPL1 PF10513.9 ORY36872.1 - 2.5e-10 41.0 0.0 2.5e-10 41.0 0.0 3.7 5 0 0 5 5 5 1 Enhancer of polycomb-like FAD_binding_2 PF00890.24 ORY36873.1 - 0.0017 17.6 0.4 0.0029 16.7 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ORY36873.1 - 0.014 14.6 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY36873.1 - 0.015 14.6 0.2 0.032 13.5 0.2 1.6 1 1 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 ORY36873.1 - 0.033 12.9 0.1 0.073 11.8 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.14 ORY36873.1 - 0.055 12.7 0.2 0.11 11.7 0.2 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORY36873.1 - 0.063 12.6 0.8 0.096 12.0 0.8 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 ORY36873.1 - 0.11 11.7 0.1 0.23 10.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family XdhC_C PF13478.6 ORY36873.1 - 0.15 12.6 0.0 0.52 10.8 0.0 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain AlaDh_PNT_C PF01262.21 ORY36873.1 - 0.17 11.1 0.1 0.33 10.2 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain cNMP_binding PF00027.29 ORY36874.1 - 0.008 16.2 0.0 0.31 11.1 0.0 2.5 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RAP1 PF07218.11 ORY36875.1 - 4.5 5.4 4.4 6.2 5.0 4.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) G-alpha PF00503.20 ORY36876.1 - 1.9e-16 60.2 0.1 2e-16 60.1 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY36876.1 - 0.0033 16.9 0.2 0.0057 16.1 0.1 1.5 1 1 1 2 2 2 1 ADP-ribosylation factor family Mg_chelatase PF01078.21 ORY36876.1 - 0.0086 15.5 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 ORY36876.1 - 0.022 14.5 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 ORY36876.1 - 0.029 13.5 0.4 0.29 10.2 0.1 1.9 1 1 1 2 2 2 0 MCM P-loop domain MMR_HSR1 PF01926.23 ORY36876.1 - 0.03 14.4 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_PrkA PF08298.11 ORY36876.1 - 0.037 13.0 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain Cytidylate_kin PF02224.18 ORY36876.1 - 0.045 13.5 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase AAA_24 PF13479.6 ORY36876.1 - 0.06 13.1 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORY36876.1 - 0.092 13.3 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ORY36876.1 - 0.13 12.2 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Roc PF08477.13 ORY36876.1 - 0.16 12.2 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 ORY36876.1 - 0.17 11.2 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region G-alpha PF00503.20 ORY36877.1 - 3.3e-30 105.5 0.1 5e-29 101.6 0.0 2.0 1 1 1 2 2 2 1 G-protein alpha subunit Arf PF00025.21 ORY36877.1 - 9.3e-12 44.7 0.4 2.5e-11 43.3 0.4 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY36877.1 - 0.0031 16.9 0.1 0.0059 16.0 0.1 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.19 ORY36877.1 - 0.022 14.3 0.1 0.038 13.6 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 ORY36877.1 - 0.052 13.0 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORY36877.1 - 0.13 12.4 0.1 0.28 11.3 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.20 ORY36878.1 - 1.6e-70 238.0 6.8 1.8e-70 237.9 6.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY36878.1 - 9.8e-13 47.9 0.1 1.9e-12 47.0 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORY36878.1 - 0.0069 16.6 0.6 0.017 15.3 0.2 1.8 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 ORY36878.1 - 0.14 11.7 0.1 0.33 10.5 0.1 1.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain G-alpha PF00503.20 ORY36879.1 - 3.1e-22 79.2 0.1 6.4e-22 78.2 0.1 1.5 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY36879.1 - 0.00076 19.0 0.3 0.0019 17.7 0.3 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY36879.1 - 0.0065 16.5 0.0 0.019 15.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 ORY36879.1 - 0.009 16.2 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 ORY36879.1 - 0.013 15.9 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 ORY36879.1 - 0.053 14.0 0.0 0.22 12.1 0.0 2.0 2 0 0 2 2 2 0 ABC transporter MCM PF00493.23 ORY36879.1 - 0.064 12.3 0.2 0.16 11.0 0.2 1.7 2 0 0 2 2 2 0 MCM P-loop domain AAA_18 PF13238.6 ORY36879.1 - 0.089 13.3 0.0 0.22 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Csm1_N PF18504.1 ORY36880.1 - 0.021 15.2 1.5 0.026 14.8 1.5 1.2 1 0 0 1 1 1 0 Csm1 N-terminal domain MCC-bdg_PDZ PF10506.9 ORY36880.1 - 0.054 13.5 0.4 0.1 12.6 0.4 1.5 1 1 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome bZIP_1 PF00170.21 ORY36880.1 - 0.12 12.5 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor TMEM52 PF14979.6 ORY36881.1 - 0.022 14.7 0.0 0.026 14.4 0.0 1.1 1 0 0 1 1 1 0 Transmembrane 52 eIF-5_eIF-2B PF01873.17 ORY36882.1 - 1.5e-16 60.3 0.1 2.3e-16 59.7 0.1 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Orthopox_B11R PF07033.11 ORY36882.1 - 0.039 13.7 0.1 0.083 12.7 0.1 1.5 1 0 0 1 1 1 0 Orthopoxvirus B11R protein eIF-5_eIF-2B PF01873.17 ORY36883.1 - 9.8e-40 135.1 0.1 1.8e-39 134.3 0.1 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 ORY36883.1 - 6.2e-20 71.1 2.3 8.1e-20 70.7 1.1 1.9 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon zf-ribbon_3 PF13248.6 ORY36883.1 - 0.66 9.5 2.9 0.49 9.9 0.2 2.0 2 0 0 2 2 2 0 zinc-ribbon domain PGA2 PF07543.12 ORY36883.1 - 1.2 9.1 6.2 4 7.4 1.8 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 Ribosomal_L2_C PF03947.18 ORY36884.1 - 5.9e-47 159.0 1.5 1.2e-46 158.0 1.5 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 ORY36884.1 - 6.3e-21 74.1 0.0 1.9e-20 72.6 0.0 1.9 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain MBOAT_2 PF13813.6 ORY36885.1 - 5e-06 26.7 1.3 1.1e-05 25.6 0.5 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Ycf70 PF17382.2 ORY36885.1 - 0.16 12.4 0.0 0.35 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized Ycf70-like Glyco_hydro_46 PF01374.18 ORY36886.1 - 1.9e-07 30.9 0.2 2.9e-07 30.3 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Glyco_hydro_46 PF01374.18 ORY36887.1 - 1.7e-27 96.4 0.1 2e-27 96.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Glyco_hydro_46 PF01374.18 ORY36888.1 - 1.6e-06 27.9 0.7 2e-06 27.6 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Pyridox_oxase_2 PF12766.7 ORY36889.1 - 3.2e-20 72.6 0.0 7e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 ORY36889.1 - 0.1 12.8 0.0 1.6 8.9 0.0 2.3 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Pyrid_oxidase_2 PF13883.6 ORY36890.1 - 2.2e-21 76.5 0.0 2.9e-21 76.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pkinase PF00069.25 ORY36891.1 - 2.4e-41 141.8 0.0 3.4e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY36891.1 - 1.4e-22 80.2 0.0 2.1e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY36891.1 - 0.001 19.0 0.1 0.11 12.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 ORY36891.1 - 0.014 14.7 0.1 0.11 11.8 0.0 2.2 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY36891.1 - 0.054 12.3 0.0 0.16 10.7 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase CD34_antigen PF06365.12 ORY36892.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family TIG_plexin PF17960.1 ORY36894.1 - 0.015 15.3 0.1 0.028 14.4 0.1 1.4 1 0 0 1 1 1 0 TIG domain NCE101 PF11654.8 ORY36894.1 - 0.053 13.2 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Non-classical export protein 1 DUF5527 PF17665.1 ORY36895.1 - 0.014 14.9 0.1 0.1 12.1 0.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5527) DUF2244 PF10003.9 ORY36895.1 - 0.017 14.8 0.2 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Gram_pos_anchor PF00746.21 ORY36895.1 - 0.019 14.9 0.0 16 5.5 0.0 3.1 3 0 0 3 3 3 0 LPXTG cell wall anchor motif DUF202 PF02656.15 ORY36895.1 - 0.021 15.3 0.1 5.6 7.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF202) RAMP4 PF06624.12 ORY36895.1 - 0.032 14.3 0.1 0.099 12.7 0.1 1.8 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 DUF5367 PF17329.2 ORY36895.1 - 0.042 14.0 0.1 1.8 8.8 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5367) DUF4381 PF14316.6 ORY36895.1 - 0.12 12.6 0.0 14 5.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) TMEM154 PF15102.6 ORY36896.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Apidaecin PF00807.17 ORY36896.1 - 0.022 14.9 3.4 0.2 11.8 0.2 2.5 2 0 0 2 2 2 0 Apidaecin DUF2076 PF09849.9 ORY36898.1 - 0.0018 18.4 8.3 0.0019 18.3 8.3 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Extensin_2 PF04554.13 ORY36900.1 - 1.3 9.1 32.5 2.2 8.4 32.5 1.3 1 0 0 1 1 1 0 Extensin-like region Ntox22 PF15527.6 ORY36901.1 - 0.03 14.4 0.7 0.059 13.4 0.7 1.4 1 1 0 1 1 1 0 Bacterial toxin 22 DUF2673 PF10880.8 ORY36901.1 - 0.23 11.6 3.8 0.35 11.0 1.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2673) ATP-synt_G PF04718.15 ORY36902.1 - 0.2 12.5 0.0 0.24 12.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ATP synthase g subunit DUF2076 PF09849.9 ORY36905.1 - 1.5 8.8 7.5 1.6 8.7 7.5 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF2076 PF09849.9 ORY36907.1 - 0.011 15.8 9.4 0.017 15.2 9.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pex14_N PF04695.13 ORY36907.1 - 0.018 15.7 1.3 0.018 15.7 1.3 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Herpes_UL56 PF04534.12 ORY36909.1 - 0.038 13.5 1.0 0.06 12.8 1.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL56 protein PH PF00169.29 ORY36910.1 - 0.00086 19.8 0.2 0.0013 19.2 0.2 1.3 1 0 0 1 1 1 1 PH domain PH_16 PF17838.1 ORY36910.1 - 0.056 13.3 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 PH domain Kelch_1 PF01344.25 ORY36910.1 - 0.086 12.4 0.2 0.2 11.2 0.2 1.6 1 0 0 1 1 1 0 Kelch motif Ank_2 PF12796.7 ORY36911.1 - 7.5e-37 125.8 0.5 1.2e-10 41.8 0.1 4.8 2 2 1 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY36911.1 - 1.9e-24 85.7 2.0 0.0003 21.3 0.1 6.7 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY36911.1 - 7.3e-21 74.0 4.2 0.094 13.1 0.1 8.2 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY36911.1 - 6.6e-16 56.8 5.3 0.5 11.1 0.0 10.7 10 1 1 11 11 11 3 Ankyrin repeat Ank PF00023.30 ORY36911.1 - 6.8e-14 51.6 10.1 1.3 9.6 0.1 9.1 8 2 1 9 9 9 4 Ankyrin repeat MFS_1 PF07690.16 ORY36912.1 - 1.7e-38 132.5 58.4 4.9e-38 130.9 58.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY36912.1 - 6.5e-12 45.0 11.5 6.5e-12 45.0 11.5 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 ORY36912.1 - 6e-09 34.9 23.0 7.1e-09 34.6 23.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 ORY36912.1 - 0.0019 16.7 4.9 0.0019 16.7 4.9 2.4 3 0 0 3 3 3 1 Transmembrane secretion effector Aminotran_1_2 PF00155.21 ORY36913.1 - 3.4e-38 131.8 0.0 5.3e-38 131.1 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORY36913.1 - 0.05 12.9 0.0 0.071 12.4 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase MFS_1 PF07690.16 ORY36914.1 - 5.7e-39 134.0 51.7 1.3e-38 132.9 51.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY36914.1 - 5.9e-09 35.3 14.9 5.9e-09 35.3 14.9 3.1 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY36915.1 - 6.6e-43 147.0 50.8 6.6e-43 147.0 50.8 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY36915.1 - 5.5e-11 42.0 11.4 5.5e-11 42.0 11.4 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter RRM_1 PF00076.22 ORY36917.1 - 1.6e-28 98.3 0.0 1.8e-13 50.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.19 ORY36917.1 - 5.4e-25 85.6 0.8 8.3e-05 22.1 0.0 6.3 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_occluded PF16842.5 ORY36917.1 - 9.4e-08 31.8 0.0 0.0018 18.1 0.0 2.6 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_5 PF13893.6 ORY36917.1 - 3.4e-06 26.7 0.0 0.054 13.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 ORY36917.1 - 0.0069 16.4 46.9 0.049 13.6 12.5 2.4 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Nab6_mRNP_bdg PF10567.9 ORY36917.1 - 0.09 12.2 1.0 0.85 9.0 0.0 2.5 1 1 1 2 2 2 0 RNA-recognition motif SET_assoc PF11767.8 ORY36917.1 - 0.17 11.6 0.0 0.66 9.6 0.0 2.0 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Presenilin PF01080.17 ORY36917.1 - 1.4 7.6 5.3 1.8 7.2 0.3 2.2 2 0 0 2 2 2 0 Presenilin TTL PF03133.15 ORY36918.1 - 2.6e-85 286.1 0.0 6.3e-85 284.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 ORY36918.1 - 3.3e-09 36.4 0.0 0.00011 21.5 0.0 2.8 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 ORY36918.1 - 5.4e-05 22.6 0.1 0.0038 16.5 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 ORY36918.1 - 0.16 11.6 0.0 0.62 9.6 0.0 1.9 3 0 0 3 3 3 0 RimK-like ATP-grasp domain Podoplanin PF05808.11 ORY36918.1 - 9.4 6.3 7.1 21 5.2 7.1 1.5 1 0 0 1 1 1 0 Podoplanin Phi_1 PF04674.12 ORY36919.1 - 0.00063 19.1 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Phosphate-induced protein 1 conserved region Peptidase_M24 PF00557.24 ORY36920.1 - 2.9e-53 180.7 0.0 3.9e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 ORY36920.1 - 9.1e-23 80.3 0.0 1.8e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Pinin_SDK_memA PF04696.13 ORY36921.1 - 2e-22 79.7 12.7 2e-22 79.7 12.7 2.1 1 1 1 2 2 2 1 pinin/SDK/memA/ protein conserved region CwsA PF10814.8 ORY36921.1 - 0.31 11.2 2.4 0.64 10.2 2.4 1.6 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA ParcG PF10274.9 ORY36922.1 - 1.6e-35 122.9 0.0 6.7e-33 114.3 0.0 2.1 2 0 0 2 2 2 2 Parkin co-regulated protein DUF2956 PF11169.8 ORY36922.1 - 0.073 13.3 0.5 1 9.6 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2956) DUF936 PF06075.12 ORY36922.1 - 3.6 6.4 9.3 4.5 6.1 9.3 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) TraP PF07296.11 ORY36923.1 - 0.14 11.3 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 TraP protein IPP-2 PF04979.14 ORY36924.1 - 4.1e-15 56.7 10.3 4.1e-15 56.7 10.3 1.5 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) Peptidase_C37 PF05416.12 ORY36924.1 - 0.27 9.7 3.6 0.32 9.5 3.6 1.0 1 0 0 1 1 1 0 Southampton virus-type processing peptidase RF-1 PF00472.20 ORY36924.1 - 0.68 9.9 3.2 0.65 9.9 1.9 1.6 1 1 1 2 2 2 0 RF-1 domain MFS_1 PF07690.16 ORY36925.1 - 1.5e-28 99.8 40.1 5.7e-28 97.9 40.1 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY36925.1 - 9e-06 24.4 17.0 9e-06 24.4 16.7 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ORY36926.1 - 3.2e-31 108.5 44.8 5.4e-30 104.5 44.8 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY36926.1 - 1e-05 24.2 15.9 1.6e-05 23.5 15.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2417 PF10329.9 ORY36926.1 - 0.17 11.3 3.1 0.1 12.0 0.3 2.1 2 0 0 2 2 2 0 Region of unknown function (DUF2417) DUF3194 PF11419.8 ORY36926.1 - 0.18 12.2 0.1 0.47 10.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3194) OATP PF03137.20 ORY36926.1 - 0.3 9.3 10.0 0.023 13.0 2.1 2.4 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Ribonuclease_T2 PF00445.18 ORY36927.1 - 5e-33 114.9 0.0 6.4e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family G-alpha PF00503.20 ORY36928.1 - 1.2e-90 304.2 0.5 1.5e-90 303.9 0.5 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY36928.1 - 1.8e-11 43.8 0.0 3.6e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORY36928.1 - 0.052 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 ORY36929.1 - 6.6e-96 321.6 4.2 7.6e-96 321.3 4.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY36929.1 - 1.1e-13 51.1 0.4 6.5e-13 48.5 0.1 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family Roc PF08477.13 ORY36929.1 - 0.00094 19.4 0.0 0.0034 17.6 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 ORY36929.1 - 0.04 13.5 1.1 0.28 10.7 0.2 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain cwf21 PF08312.12 ORY36929.1 - 2.1 8.6 5.5 1.1 9.5 2.6 2.1 2 0 0 2 2 2 0 cwf21 domain G-alpha PF00503.20 ORY36930.1 - 8.6e-106 354.1 0.1 1e-105 353.8 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY36930.1 - 1.8e-16 60.1 0.9 1.1e-12 47.7 0.3 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 ORY36930.1 - 6.5e-06 26.4 0.3 0.092 13.0 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 ORY36930.1 - 1.6e-05 24.4 1.7 0.0046 16.3 0.2 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Ras PF00071.22 ORY36930.1 - 0.035 13.7 0.6 2.5 7.7 0.2 2.3 2 0 0 2 2 2 0 Ras family MMR_HSR1 PF01926.23 ORY36930.1 - 0.054 13.6 0.1 1.5 8.9 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 ORY36930.1 - 0.15 11.4 0.2 0.58 9.5 0.0 2.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family G-alpha PF00503.20 ORY36931.1 - 2.5e-64 217.7 0.0 3.2e-64 217.3 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY36931.1 - 1e-11 44.6 1.9 3.7e-08 33.0 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 ORY36931.1 - 0.00014 22.1 1.1 0.18 12.0 0.0 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 ORY36931.1 - 0.0024 17.3 0.7 0.28 10.5 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY36931.1 - 0.035 14.2 0.2 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY36931.1 - 0.076 12.8 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DAP3 PF10236.9 ORY36931.1 - 0.088 12.0 0.1 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 FtsK_SpoIIIE PF01580.18 ORY36931.1 - 0.2 11.0 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.20 ORY36932.1 - 1.6e-80 270.9 0.0 1.9e-80 270.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY36932.1 - 4.3e-11 42.6 0.0 1.2e-10 41.1 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Cofilin_ADF PF00241.20 ORY36933.1 - 1.2e-25 89.6 0.0 2.6e-13 49.8 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein G-alpha PF00503.20 ORY36934.1 - 3.2e-94 316.0 0.0 3.8e-94 315.8 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY36934.1 - 1.1e-16 60.8 0.5 7.1e-11 41.9 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY36934.1 - 8.3e-05 22.2 1.0 0.0078 15.8 0.4 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORY36934.1 - 0.00013 21.4 0.8 0.018 14.4 0.3 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY36934.1 - 0.00018 21.7 0.9 0.19 12.0 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 ORY36934.1 - 0.0042 16.5 0.9 2.3 7.6 0.1 2.5 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 ORY36934.1 - 0.0058 16.4 1.6 0.01 15.6 0.1 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 ORY36934.1 - 0.15 12.1 0.3 2.1 8.5 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase adh_short PF00106.25 ORY36935.1 - 1.8e-19 70.0 0.0 2.5e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY36935.1 - 4.8e-08 32.8 0.0 7.2e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY36935.1 - 0.0028 17.6 0.0 0.0041 17.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY36935.1 - 0.025 14.0 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY36935.1 - 0.048 12.8 0.0 0.066 12.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 ORY36935.1 - 0.068 12.9 0.2 0.26 11.1 0.2 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Cpn60_TCP1 PF00118.24 ORY36936.1 - 6.2e-162 539.6 14.0 7.1e-162 539.4 14.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.17 ORY36936.1 - 0.039 14.3 0.4 0.24 11.8 0.1 2.4 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor DUF356 PF04009.12 ORY36936.1 - 0.045 14.0 0.1 0.22 11.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF356) Adhesin_P1_N PF18652.1 ORY36936.1 - 0.82 9.7 3.1 9.6 6.3 0.3 2.8 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain PBP_sp32 PF07222.12 ORY36937.1 - 3.2 7.1 11.7 5.8 6.3 0.2 2.6 2 1 1 3 3 3 0 Proacrosin binding protein sp32 CHD5 PF04420.14 ORY36938.1 - 5.7e-39 133.5 4.5 8.7e-39 132.9 4.5 1.2 1 0 0 1 1 1 1 CHD5-like protein Herpes_env PF01673.18 ORY36938.1 - 0.08 11.9 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Glyco_transf_34 PF05637.12 ORY36939.1 - 1.3e-05 25.0 0.8 1.9e-05 24.5 0.8 1.4 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Cation_efflux PF01545.21 ORY36940.1 - 3.5e-38 131.3 1.2 4.4e-38 131.0 1.2 1.1 1 0 0 1 1 1 1 Cation efflux family Importin_rep_2 PF18786.1 ORY36940.1 - 0.12 12.2 0.3 0.53 10.2 0.3 2.1 1 0 0 1 1 1 0 Importin 13 repeat GtrA PF04138.14 ORY36940.1 - 1.5 9.1 6.7 1.1 9.5 1.1 2.5 2 1 0 2 2 2 0 GtrA-like protein ADH_zinc_N PF00107.26 ORY36941.1 - 3.5e-08 33.5 0.4 3.5e-08 33.5 0.4 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY36941.1 - 5.1e-08 32.8 0.2 4.1e-07 29.9 0.2 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 ORY36941.1 - 0.072 12.4 0.3 0.072 12.4 0.3 2.3 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Pox_I6 PF04595.13 ORY36941.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus I6-like family RP1-2 PF12042.8 ORY36941.1 - 0.65 9.8 2.6 1.9 8.4 0.8 2.0 2 0 0 2 2 2 0 Tubuliform egg casing silk strands structural domain DUF3952 PF13130.6 ORY36986.1 - 0.038 14.2 0.0 0.053 13.7 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3952) DUF1629 PF07791.11 ORY36986.1 - 0.1 12.8 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1629) WD40 PF00400.32 ORY36987.1 - 9.3e-63 206.7 22.3 4.7e-10 39.9 0.9 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY36987.1 - 4.4e-23 81.4 3.5 0.004 17.4 0.0 5.8 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain TIR_2 PF13676.6 ORY36987.1 - 3e-16 60.1 0.0 6.6e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 TIR domain Nup160 PF11715.8 ORY36987.1 - 3.3e-15 55.7 9.9 0.026 13.2 0.1 6.2 1 1 5 6 6 6 5 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY36987.1 - 9.5e-11 41.6 0.3 0.083 12.2 0.1 5.1 1 1 2 4 4 4 4 WD40-like domain NACHT PF05729.12 ORY36987.1 - 2.3e-09 37.4 0.0 6.7e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Ge1_WD40 PF16529.5 ORY36987.1 - 1.3e-07 30.9 11.1 0.029 13.3 0.2 6.0 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 ORY36987.1 - 3.5e-06 27.5 0.0 1.3e-05 25.6 0.0 1.9 2 0 0 2 2 1 1 AAA ATPase domain DUF4597 PF15366.6 ORY36987.1 - 0.00054 19.6 0.7 12 5.8 0.0 4.5 1 1 4 5 5 5 1 Domain of unknown function (DUF4597) AAA_7 PF12775.7 ORY36987.1 - 0.0026 17.3 0.0 0.0065 16.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region TIR PF01582.20 ORY36987.1 - 0.0097 15.7 0.0 0.028 14.2 0.0 1.8 1 0 0 1 1 1 1 TIR domain CNH PF00780.22 ORY36987.1 - 0.021 14.4 0.1 36 3.9 0.0 4.0 4 1 1 5 5 5 0 CNH domain DWNN PF08783.11 ORY36987.1 - 0.05 13.9 1.1 0.14 12.5 0.2 2.2 2 0 0 2 2 2 0 DWNN domain DUF5570 PF17731.1 ORY36987.1 - 0.85 9.7 15.2 13 5.9 0.9 4.8 1 1 4 5 5 5 0 Family of unknown function (DUF5570) UPF0506 PF11703.8 ORY36987.1 - 3 8.3 4.6 3.8e+02 1.6 1.1 5.0 6 0 0 6 6 6 0 UPF0506 hNIFK_binding PF12196.8 ORY36988.1 - 0.71 9.4 5.6 0.16 11.5 1.3 2.2 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK Es2 PF09751.9 ORY36989.1 - 2e-78 265.1 7.8 4.4e-78 264.0 5.0 1.9 2 0 0 2 2 2 2 Nuclear protein Es2 RGS PF00615.19 ORY36990.1 - 2.4e-06 27.8 2.4 0.002 18.4 0.0 3.0 3 0 0 3 3 3 2 Regulator of G protein signaling domain 7tm_3 PF00003.22 ORY36990.1 - 0.00018 21.3 20.0 0.0011 18.8 20.1 2.0 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Pkinase PF00069.25 ORY36991.1 - 7.7e-34 117.2 0.0 9.2e-33 113.7 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY36991.1 - 3.9e-12 46.0 0.0 7.9e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY36991.1 - 0.026 13.3 0.6 0.051 12.4 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Choline_kinase PF01633.20 ORY36991.1 - 0.044 13.4 0.0 0.044 13.4 0.0 2.5 2 1 1 3 3 3 0 Choline/ethanolamine kinase Seryl_tRNA_N PF02403.22 ORY36991.1 - 0.052 13.8 14.3 0.83 9.9 2.0 2.8 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ApoC-I PF04691.12 ORY36991.1 - 0.082 12.8 0.2 1.9 8.5 0.2 2.6 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) T3SS_needle_F PF09392.10 ORY36991.1 - 0.32 11.2 4.8 0.68 10.2 1.9 2.7 2 0 0 2 2 2 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF Sec8_exocyst PF04048.14 ORY36991.1 - 0.39 10.6 13.4 0.047 13.6 8.0 2.0 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain XhlA PF10779.9 ORY36991.1 - 0.65 10.2 4.5 3.5 7.9 0.2 2.8 2 0 0 2 2 2 0 Haemolysin XhlA IFT20 PF14931.6 ORY36991.1 - 0.97 9.6 14.1 0.19 11.9 4.6 2.8 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 UPF0242 PF06785.11 ORY36991.1 - 2.5 8.2 30.0 0.026 14.6 11.4 2.7 1 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus FadA PF09403.10 ORY36991.1 - 3.2 8.3 10.3 0.25 11.8 0.7 2.7 2 1 0 2 2 2 0 Adhesion protein FadA HIP1_clath_bdg PF16515.5 ORY36991.1 - 5.2 7.8 19.0 2 9.1 2.6 3.2 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF16 PF01519.16 ORY36991.1 - 6.7 7.3 19.0 3.9 8.0 5.9 2.9 2 1 1 3 3 3 0 Protein of unknown function DUF16 ATG16 PF08614.11 ORY36991.1 - 7.4 6.7 20.6 7.7 6.7 5.7 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Lactonase PF10282.9 ORY36993.1 - 1.6e-20 73.6 0.0 1.2e-12 47.8 0.0 2.1 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller ABC_tran PF00005.27 ORY36994.1 - 7.3e-44 149.6 0.6 1.8e-29 103.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORY36994.1 - 3.8e-25 89.1 0.7 3.8e-25 89.1 0.7 3.0 2 1 1 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 ORY36994.1 - 4.9e-12 45.8 2.6 0.00031 20.3 0.0 3.3 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY36994.1 - 2.7e-08 33.9 1.6 0.0074 16.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY36994.1 - 2.8e-08 34.3 0.1 0.0013 19.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 ORY36994.1 - 8.5e-08 31.8 0.6 0.014 15.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 ORY36994.1 - 2.8e-07 30.7 5.8 0.0042 16.9 0.2 3.3 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ORY36994.1 - 4.8e-07 30.5 0.0 0.059 13.9 0.1 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ORY36994.1 - 1.4e-06 28.3 0.7 0.0073 16.2 0.5 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 ORY36994.1 - 1.2e-05 25.2 0.6 0.058 13.1 0.4 2.3 2 0 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.18 ORY36994.1 - 1.2e-05 24.8 0.3 0.077 12.3 0.2 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF87 PF01935.17 ORY36994.1 - 1.8e-05 25.0 1.8 0.0085 16.2 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 ORY36994.1 - 2e-05 23.7 0.9 0.05 12.5 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 ORY36994.1 - 2.3e-05 24.7 0.4 0.28 11.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 ORY36994.1 - 3.4e-05 24.0 2.7 0.015 15.4 0.5 2.4 2 0 0 2 2 2 2 Dynamin family T2SSE PF00437.20 ORY36994.1 - 5.3e-05 22.4 0.4 0.23 10.5 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF815 PF05673.13 ORY36994.1 - 6.5e-05 22.2 0.4 0.12 11.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_7 PF12775.7 ORY36994.1 - 6.9e-05 22.4 0.1 0.37 10.3 0.1 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_30 PF13604.6 ORY36994.1 - 7e-05 22.6 0.3 0.41 10.3 0.0 2.8 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 ORY36994.1 - 0.00046 20.1 2.1 0.15 11.9 0.3 2.6 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.12 ORY36994.1 - 0.00056 19.2 1.0 0.15 11.3 0.2 2.3 2 0 0 2 2 2 1 Zeta toxin KAP_NTPase PF07693.14 ORY36994.1 - 0.00067 19.0 0.0 0.024 13.9 0.0 2.2 2 0 0 2 2 2 1 KAP family P-loop domain NB-ARC PF00931.22 ORY36994.1 - 0.00084 18.6 0.3 0.51 9.5 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Roc PF08477.13 ORY36994.1 - 0.00096 19.4 0.4 2.1 8.6 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 ORY36994.1 - 0.0022 18.6 0.1 2.4 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ORY36994.1 - 0.0032 17.8 0.2 2.5 8.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 ORY36994.1 - 0.0037 17.0 0.3 5.7 6.6 0.1 3.2 4 0 0 4 4 3 0 IstB-like ATP binding protein cobW PF02492.19 ORY36994.1 - 0.0049 16.5 1.4 0.59 9.7 0.4 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.25 ORY36994.1 - 0.0058 16.3 0.0 2.6 7.7 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.14 ORY36994.1 - 0.012 15.6 1.0 1.2 9.0 0.3 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Adeno_IVa2 PF02456.15 ORY36994.1 - 0.012 14.5 0.2 3.5 6.3 0.1 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein PduV-EutP PF10662.9 ORY36994.1 - 0.014 15.1 1.3 3.9 7.2 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 ORY36994.1 - 0.02 14.9 0.1 1.5 8.8 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MeaB PF03308.16 ORY36994.1 - 0.022 13.7 0.2 3.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 ORY36994.1 - 0.028 14.4 1.2 21 5.1 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Ploopntkinase3 PF18751.1 ORY36994.1 - 0.033 14.1 0.3 5.6 6.8 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ATP_bind_1 PF03029.17 ORY36994.1 - 0.048 13.4 1.4 9 6.0 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 ORY36994.1 - 0.058 13.0 0.3 1.3 8.6 0.1 2.8 3 0 0 3 3 3 0 AAA domain Pox_A32 PF04665.12 ORY36994.1 - 0.078 12.4 0.2 8.2 5.8 0.0 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein Sigma54_activat PF00158.26 ORY36994.1 - 0.079 12.7 0.1 4.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 ORY36994.1 - 0.084 13.3 0.7 20 5.6 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.7 ORY36994.1 - 0.093 11.6 1.0 1.8 7.4 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain ATPase_2 PF01637.18 ORY36994.1 - 0.11 12.4 0.0 3.8 7.3 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 ORY36994.1 - 0.14 12.4 0.3 11 6.1 0.3 2.6 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.21 ORY36994.1 - 0.14 11.8 0.4 3.3 7.3 0.1 2.3 2 0 0 2 2 2 0 Guanylate kinase AAA_28 PF13521.6 ORY36994.1 - 0.18 12.0 1.8 4.4 7.5 0.5 2.4 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 ORY36994.1 - 0.4 10.4 1.4 27 4.4 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase LtrA PF06772.11 ORY36995.1 - 3.9e-21 75.7 15.7 6e-21 75.1 15.7 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) TMEM208_SND2 PF05620.11 ORY36995.1 - 0.16 11.7 5.4 0.28 10.9 0.1 3.2 3 1 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 CsgE PF10627.9 ORY36996.1 - 0.13 12.5 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Curli assembly protein CsgE G8 PF10162.9 ORY36997.1 - 2.2e-26 92.4 0.6 1.5e-25 89.7 0.4 2.3 2 0 0 2 2 2 1 G8 domain DUSP PF06337.12 ORY36998.1 - 2.3e-06 28.1 0.0 3.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 DUSP domain zf-UBP PF02148.19 ORY36998.1 - 0.00016 22.0 1.5 0.00016 22.0 1.5 2.1 1 1 1 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein F-box_4 PF15966.5 ORY36999.1 - 0.035 14.0 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 F-box F-box-like PF12937.7 ORY36999.1 - 0.068 13.1 0.4 0.24 11.3 0.1 1.9 2 0 0 2 2 2 0 F-box-like zf-UBP PF02148.19 ORY37000.1 - 3.5e-09 36.9 3.1 5.4e-09 36.2 3.1 1.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein DUSP PF06337.12 ORY37000.1 - 0.0068 17.0 0.0 0.011 16.3 0.0 1.3 1 0 0 1 1 1 1 DUSP domain AAA PF00004.29 ORY37001.1 - 8.7e-13 48.8 0.0 3e-06 27.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 ORY37001.1 - 0.00015 21.1 0.0 0.00066 18.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 ORY37001.1 - 0.0025 18.2 0.6 0.013 15.9 0.0 2.4 3 0 0 3 3 3 1 RNA helicase AAA_16 PF13191.6 ORY37001.1 - 0.0065 16.9 0.0 0.013 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 ORY37001.1 - 0.028 14.9 0.1 0.1 13.1 0.1 2.0 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 ORY37001.1 - 0.032 13.7 0.0 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 ORY37001.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain CDC45 PF02724.14 ORY37001.1 - 0.083 11.2 7.8 0.14 10.4 7.8 1.3 1 0 0 1 1 1 0 CDC45-like protein AAA_5 PF07728.14 ORY37001.1 - 0.11 12.4 0.0 0.46 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 ORY37001.1 - 0.18 11.6 2.9 0.84 9.4 2.9 2.0 1 1 0 1 1 1 0 AAA domain Pox_Ag35 PF03286.14 ORY37001.1 - 0.38 10.5 5.2 0.9 9.3 5.2 1.6 1 0 0 1 1 1 0 Pox virus Ag35 surface protein AAA_18 PF13238.6 ORY37001.1 - 4.3 7.9 6.2 0.57 10.7 0.8 2.4 2 1 0 2 2 1 0 AAA domain Cellulase PF00150.18 ORY37003.1 - 0.061 12.7 0.0 0.34 10.3 0.0 2.0 2 1 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) STIL_N PF15253.6 ORY37005.1 - 2.1e-14 53.3 0.2 2.3e-14 53.2 0.2 1.0 1 0 0 1 1 1 1 SCL-interrupting locus protein N-terminus DUF3910 PF13049.6 ORY37005.1 - 0.17 12.2 0.0 0.9 9.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3910) Peptidase_S10 PF00450.22 ORY37011.1 - 4e-64 217.6 2.1 6.5e-63 213.6 2.1 2.0 1 1 0 1 1 1 1 Serine carboxypeptidase MFS_1 PF07690.16 ORY37012.1 - 1.8e-09 37.0 29.1 0.00049 19.1 22.3 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_3 PF05977.13 ORY37012.1 - 0.049 12.0 1.5 0.11 10.9 1.5 1.5 1 0 0 1 1 1 0 Transmembrane secretion effector MPS2 PF17060.5 ORY37013.1 - 0.012 14.9 1.1 0.015 14.6 1.1 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 PV-1 PF06637.11 ORY37013.1 - 0.013 14.3 2.4 0.026 13.3 2.4 1.4 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DUF4407 PF14362.6 ORY37013.1 - 0.095 12.0 2.6 0.12 11.7 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ABC_tran_CTD PF16326.5 ORY37013.1 - 0.18 12.1 7.9 0.2 11.9 6.5 1.8 1 1 1 2 2 2 0 ABC transporter C-terminal domain Herpes_BLRF2 PF05812.12 ORY37013.1 - 1.1 9.4 7.5 1.1 9.4 1.3 2.8 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein ZapB PF06005.12 ORY37013.1 - 2.8 8.4 14.2 5.1e+02 1.2 14.2 2.8 1 1 0 1 1 1 0 Cell division protein ZapB MSA-2c PF12238.8 ORY37014.1 - 0.078 13.0 1.4 0.093 12.7 1.4 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c BAR PF03114.18 ORY37015.1 - 4.2e-40 137.9 4.4 5.7e-40 137.4 4.4 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 ORY37015.1 - 7.4e-17 60.7 0.1 1.2e-16 60.0 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY37015.1 - 4.9e-14 51.9 0.1 7.7e-14 51.3 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY37015.1 - 4.2e-11 42.4 0.0 7.5e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.10 ORY37015.1 - 0.32 10.5 4.4 0.23 11.0 1.0 2.1 2 0 0 2 2 2 0 Vps5 C terminal like DUF3678 PF12435.8 ORY37015.1 - 0.32 10.4 3.6 1.4 8.4 3.6 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) AATF-Che1 PF13339.6 ORY37015.1 - 7.3 7.3 8.5 74 4.0 8.5 2.3 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor Inhibitor_I78 PF11720.8 ORY37016.1 - 1e-08 35.1 0.0 1.3e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 ORY37016.1 - 0.0012 19.5 0.0 0.0014 19.2 0.0 1.2 1 0 0 1 1 1 1 Potato inhibitor I family PAN_1 PF00024.26 ORY37017.1 - 9.8e-05 22.3 3.1 0.12 12.4 0.0 3.9 4 0 0 4 4 4 2 PAN domain PAN_4 PF14295.6 ORY37017.1 - 0.0028 17.5 0.8 0.0028 17.5 0.8 4.9 5 0 0 5 5 5 2 PAN domain PAN_3 PF08277.12 ORY37017.1 - 0.017 14.9 8.3 0.13 12.1 0.6 3.9 4 0 0 4 4 4 0 PAN-like domain NdhM PF10664.9 ORY37017.1 - 0.064 13.5 0.0 8.8 6.6 0.0 2.9 3 0 0 3 3 3 0 Cyanobacterial and plastid NDH-1 subunit M PAN_1 PF00024.26 ORY37018.1 - 1.7e-23 82.3 0.9 0.0012 18.7 0.1 5.2 5 0 0 5 5 5 5 PAN domain PAN_4 PF14295.6 ORY37018.1 - 3e-12 46.2 40.6 0.00046 20.0 0.2 6.6 7 0 0 7 7 7 5 PAN domain PAN_3 PF08277.12 ORY37018.1 - 9.4e-09 35.0 41.1 0.032 14.1 1.3 6.8 7 0 0 7 7 7 5 PAN-like domain YedD PF13987.6 ORY37018.1 - 1.1 9.2 3.6 35 4.3 0.0 3.2 4 0 0 4 4 4 0 YedD-like protein Metallophos PF00149.28 ORY37019.1 - 2.5e-14 54.3 4.0 2.9e-14 54.1 4.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pet100 PF09803.9 ORY37020.1 - 2.4e-07 31.2 0.1 2.7e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 Pet100 Caprin-1_C PF12287.8 ORY37021.1 - 0.00016 22.0 5.8 0.00028 21.1 5.8 1.4 1 0 0 1 1 1 1 Cytoplasmic activation/proliferation-associated protein-1 C term PNP_UDP_1 PF01048.20 ORY37022.1 - 2.4e-28 99.0 1.0 2.9e-26 92.2 1.0 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily Peptidase_S28 PF05577.12 ORY37023.1 - 2.3e-25 89.3 1.7 1.2e-21 77.1 0.8 3.3 1 1 1 2 2 2 2 Serine carboxypeptidase S28 ELFV_dehydrog_N PF02812.18 ORY37024.1 - 6.7e-08 32.5 0.0 1.1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Kinesin PF00225.23 ORY37026.1 - 1e-91 307.3 0.6 1e-91 307.3 0.6 2.7 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ORY37026.1 - 5.3e-21 75.1 0.0 4.4e-13 49.4 0.0 3.0 2 0 0 2 2 2 2 Microtubule binding Pox_A_type_inc PF04508.12 ORY37026.1 - 0.4 10.6 10.5 21 5.2 0.1 6.4 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat Cas6 PF09559.10 ORY37026.1 - 0.59 10.1 6.8 1.4 8.8 6.7 1.6 1 0 0 1 1 1 0 Cas6 Crispr ATG16 PF08614.11 ORY37027.1 - 0.11 12.7 1.4 0.15 12.2 1.4 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Tim17 PF02466.19 ORY37028.1 - 2.7e-34 117.9 7.0 3.8e-34 117.4 7.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Serine_protease PF18405.1 ORY37028.1 - 0.0033 16.6 0.1 0.0055 15.9 0.1 1.3 1 0 0 1 1 1 1 Gammaproteobacterial serine protease Carboxyl_trans PF01039.22 ORY37029.1 - 2.1e-118 396.1 0.0 2.7e-118 395.7 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain FAD_binding_4 PF01565.23 ORY37029.1 - 0.32 10.7 1.8 0.57 9.9 0.0 2.4 3 0 0 3 3 3 0 FAD binding domain DUF1447 PF07288.11 ORY37030.1 - 0.14 12.2 3.7 2.6 8.2 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1447) hGDE_central PF14702.6 ORY37030.1 - 0.19 11.4 4.4 0.3 10.7 4.4 1.3 1 0 0 1 1 1 0 Central domain of human glycogen debranching enzyme FtsQ PF03799.15 ORY37030.1 - 0.36 11.7 2.3 0.36 11.7 0.4 1.9 2 1 0 2 2 2 0 Cell division protein FtsQ DUF1269 PF06897.12 ORY37030.1 - 0.64 10.3 2.6 0.83 10.0 0.5 2.2 1 1 1 3 3 3 0 Protein of unknown function (DUF1269) DUF4250 PF14056.6 ORY37030.1 - 2.8 8.0 9.2 1.2 9.1 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) SbcD_C PF12320.8 ORY37030.1 - 4 7.8 9.2 11 6.4 4.3 3.1 1 1 2 3 3 3 0 Type 5 capsule protein repressor C-terminal domain UL11 PF11094.8 ORY37030.1 - 4.3 7.3 4.9 8.1 6.4 0.1 3.0 3 0 0 3 3 3 0 Membrane-associated tegument protein ECH_1 PF00378.20 ORY37031.1 - 2.5e-35 122.0 0.0 2.9e-35 121.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY37031.1 - 2.5e-25 89.7 0.0 2.9e-25 89.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase XAP5 PF04921.14 ORY37032.1 - 2.2e-70 237.4 1.4 2.6e-70 237.1 1.4 1.0 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF4690 PF15756.5 ORY37033.1 - 0.071 13.7 0.4 0.31 11.7 0.4 2.2 1 0 0 1 1 1 0 Small Novel Rich in Cartilage Putative_PNPOx PF01243.20 ORY37033.1 - 0.13 12.5 1.8 0.98 9.7 0.1 2.5 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase SecY PF00344.20 ORY37034.1 - 3.6e-37 128.3 11.6 4.3e-37 128.0 11.6 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 ORY37034.1 - 1.6e-10 40.7 0.0 4.1e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p FPP PF05911.11 ORY37035.1 - 0.00097 17.5 10.5 0.00097 17.5 10.5 7.6 2 2 4 6 6 6 3 Filament-like plant protein, long coiled-coil ATG16 PF08614.11 ORY37035.1 - 0.0051 17.1 8.9 0.0051 17.1 8.9 10.6 2 2 7 9 9 9 4 Autophagy protein 16 (ATG16) DHR10 PF18595.1 ORY37035.1 - 0.0069 16.4 5.0 0.0069 16.4 5.0 14.4 6 5 7 16 16 16 2 Designed helical repeat protein 10 domain NAD_binding_5 PF07994.12 ORY37035.1 - 1.7 7.9 14.2 0.8 9.0 1.2 3.7 3 0 0 3 3 3 0 Myo-inositol-1-phosphate synthase DUF1748 PF08520.10 ORY37037.1 - 5.3e-16 58.3 0.0 5.9e-16 58.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Mito_carr PF00153.27 ORY37040.1 - 9.6e-31 105.6 8.2 6.4e-13 48.4 0.1 4.7 2 2 2 4 4 4 4 Mitochondrial carrier protein Glyco_hydro_18 PF00704.28 ORY37042.1 - 4.7e-05 23.3 3.7 0.00034 20.4 3.5 2.3 2 1 0 2 2 2 1 Glycosyl hydrolases family 18 IgaA PF07095.11 ORY37043.1 - 0.012 13.6 0.5 1.2 7.0 0.1 2.1 2 0 0 2 2 2 0 Intracellular growth attenuator protein IgaA Glyco_hydro_18 PF00704.28 ORY37044.1 - 9.3e-05 22.3 0.1 0.00016 21.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF5344 PF17279.2 ORY37045.1 - 0.015 15.8 1.6 0.58 10.8 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5344) JAKMIP_CC3 PF16034.5 ORY37045.1 - 0.017 15.1 1.4 0.028 14.4 1.4 1.4 1 1 0 1 1 1 0 JAKMIP CC3 domain DUF2897 PF11446.8 ORY37045.1 - 0.033 14.1 0.1 0.055 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) BLOC1_2 PF10046.9 ORY37045.1 - 0.09 13.1 1.8 0.27 11.6 0.4 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CCDC92 PF14916.6 ORY37045.1 - 0.09 12.6 0.1 17 5.3 0.0 2.4 2 0 0 2 2 2 0 Coiled-coil domain of unknown function ApoO PF09769.9 ORY37045.1 - 0.16 11.9 0.4 0.28 11.1 0.4 1.5 1 1 0 1 1 1 0 Apolipoprotein O V-SNARE_C PF12352.8 ORY37046.1 - 9e-08 32.3 0.2 2.3e-07 31.0 0.2 1.7 1 1 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 ORY37046.1 - 2.4e-06 27.3 0.1 2.9e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 Sec20 E2F_TDP PF02319.20 ORY37046.1 - 0.031 14.3 0.3 0.045 13.8 0.3 1.3 1 1 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain RWP-RK PF02042.15 ORY37046.1 - 0.079 12.9 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 RWP-RK domain BSMAP PF12280.8 ORY37046.1 - 0.13 12.4 0.1 0.15 12.3 0.1 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein DUF2116 PF09889.9 ORY37046.1 - 0.13 12.2 2.2 0.13 12.2 0.5 1.8 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) ABC2_membrane PF01061.24 ORY37047.1 - 1.9e-66 223.5 61.9 2.2e-39 135.1 25.5 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 ORY37047.1 - 3.5e-37 128.0 0.0 2.9e-17 63.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ORY37047.1 - 4.1e-25 87.5 7.5 8.3e-18 64.1 0.1 3.2 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 ORY37047.1 - 3.3e-13 49.5 44.9 3.1e-08 33.1 11.8 2.7 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 ORY37047.1 - 2.9e-08 33.9 0.0 0.00031 20.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_trans_N PF14510.6 ORY37047.1 - 7.5e-06 26.5 0.0 1.6e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 ORY37047.1 - 7.9e-06 26.3 0.0 0.48 10.8 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORY37047.1 - 1.2e-05 25.3 0.2 0.011 15.6 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 ORY37047.1 - 8.8e-05 22.8 0.1 0.92 9.8 0.1 2.9 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 ORY37047.1 - 9.4e-05 22.1 0.1 0.34 10.4 0.1 3.0 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 ORY37047.1 - 0.00024 20.7 6.5 0.0069 16.1 0.3 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain NACHT PF05729.12 ORY37047.1 - 0.0019 18.2 0.1 1.6 8.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 ORY37047.1 - 0.0022 18.3 0.0 0.4 11.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 ORY37047.1 - 0.0026 18.3 0.1 3.4 8.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 ORY37047.1 - 0.0047 17.0 0.2 1.3 9.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 ORY37047.1 - 0.011 15.9 0.1 3.9 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ORY37047.1 - 0.012 16.1 0.7 11 6.4 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 ORY37047.1 - 0.021 15.0 0.3 7.5 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 ORY37047.1 - 0.024 14.2 0.4 1.8 8.1 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 ORY37047.1 - 0.069 12.6 1.9 5.9 6.2 0.0 3.3 4 0 0 4 4 3 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORY37047.1 - 0.082 13.4 0.3 0.27 11.7 0.1 2.0 2 0 0 2 2 1 0 AAA domain Roc PF08477.13 ORY37047.1 - 0.12 12.6 0.3 3.6 7.8 0.2 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 ORY37047.1 - 0.22 11.2 4.6 6.8 6.4 1.0 2.9 3 0 0 3 3 3 0 AAA domain Phosphoesterase PF04185.14 ORY37048.1 - 6.2e-07 28.9 3.1 7.6e-07 28.6 3.1 1.0 1 0 0 1 1 1 1 Phosphoesterase family Ribosomal_L22 PF00237.19 ORY37049.1 - 1.2e-07 31.9 0.0 2.2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e NAD_binding_8 PF13450.6 ORY37050.1 - 1.2e-07 31.8 0.0 1.4e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY37050.1 - 5.5e-07 29.5 0.2 6e-07 29.4 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY37050.1 - 8.1e-07 28.1 0.0 9.1e-07 27.9 0.0 1.0 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 ORY37050.1 - 3.5e-06 26.6 0.0 3.5e-06 26.6 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 ORY37050.1 - 5.8e-06 25.7 0.0 5.9e-06 25.7 0.0 1.0 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 ORY37050.1 - 8.3e-06 25.2 0.0 8.3e-06 25.2 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ORY37050.1 - 2.4e-05 23.8 0.0 2.6e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 ORY37050.1 - 3.2e-05 23.2 0.1 3.4e-05 23.1 0.1 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 ORY37050.1 - 3.3e-05 23.9 0.0 3.6e-05 23.8 0.0 1.0 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ORY37050.1 - 0.00015 21.1 0.0 0.00016 21.0 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY37050.1 - 0.00046 19.5 0.0 0.0005 19.4 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 ORY37050.1 - 0.0012 18.0 0.1 0.0012 18.0 0.1 1.0 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 ORY37050.1 - 0.002 18.6 0.0 0.0022 18.5 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 ORY37050.1 - 0.0029 17.8 0.1 0.0033 17.7 0.1 1.0 1 0 0 1 1 1 1 TrkA-N domain FMO-like PF00743.19 ORY37050.1 - 0.0037 15.8 0.0 0.0039 15.7 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Trp_halogenase PF04820.14 ORY37050.1 - 0.0042 16.0 0.2 0.0043 16.0 0.2 1.0 1 0 0 1 1 1 1 Tryptophan halogenase GIDA PF01134.22 ORY37050.1 - 0.005 16.0 0.1 0.0051 15.9 0.1 1.0 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 ORY37050.1 - 0.026 13.8 0.1 0.029 13.7 0.1 1.1 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 ORY37050.1 - 0.052 14.0 0.0 0.052 14.0 0.0 1.1 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 ORY37050.1 - 0.15 11.9 0.1 0.16 11.8 0.1 1.0 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_28 PF00295.17 ORY37051.1 - 1.9e-73 247.3 17.2 2.5e-73 247.0 17.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Methyltransf_20 PF12147.8 ORY37051.1 - 0.018 14.2 0.1 0.035 13.3 0.0 1.4 2 0 0 2 2 2 0 Putative methyltransferase NDK PF00334.19 ORY37052.1 - 3.3e-51 172.8 0.0 4e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase NYD-SP28 PF14772.6 ORY37053.1 - 3.2e-15 56.0 17.7 3.2e-15 56.0 17.7 4.9 3 1 1 4 4 4 2 Sperm tail DASH_Dam1 PF08653.10 ORY37053.1 - 2.3 8.1 5.3 60 3.5 0.3 3.9 3 0 0 3 3 3 0 DASH complex subunit Dam1 Pex2_Pex12 PF04757.14 ORY37054.1 - 3.4e-10 39.9 0.0 4.8e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region TFIID_30kDa PF03540.13 ORY37055.1 - 2e-11 43.7 0.6 3.1e-11 43.0 0.6 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit CBFD_NFYB_HMF PF00808.23 ORY37055.1 - 0.016 15.5 0.6 0.18 12.1 0.6 2.0 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF4 PF05236.14 ORY37055.1 - 0.045 13.5 0.1 0.051 13.3 0.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family UBN_AB PF14075.6 ORY37056.1 - 0.035 13.8 1.4 0.04 13.6 1.4 1.2 1 0 0 1 1 1 0 Ubinuclein conserved middle domain CPSF100_C PF13299.6 ORY37056.1 - 1.1 9.4 7.3 1.3 9.2 7.3 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal YL1 PF05764.13 ORY37056.1 - 1.6 8.8 29.0 1.7 8.7 29.0 1.0 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 ORY37056.1 - 2.6 6.2 23.2 2.7 6.2 23.2 1.0 1 0 0 1 1 1 0 CDC45-like protein POX PF07526.11 ORY37056.1 - 3.9 8.1 5.1 5 7.7 5.1 1.2 1 0 0 1 1 1 0 Associated with HOX FmiP_Thoc5 PF09766.9 ORY37056.1 - 4 6.6 11.5 4.2 6.6 11.5 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 RR_TM4-6 PF06459.12 ORY37056.1 - 4.1 7.1 9.2 4.8 6.9 9.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 ORY37056.1 - 4.9 7.6 7.5 6 7.3 7.5 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 PNISR PF15996.5 ORY37056.1 - 6 7.1 15.5 6.7 6.9 15.5 1.0 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR PI3K_1B_p101 PF10486.9 ORY37056.1 - 6.4 4.4 7.6 6.6 4.4 7.6 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SAPS PF04499.15 ORY37056.1 - 6.9 5.3 12.0 7.2 5.3 12.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Vfa1 PF08432.10 ORY37056.1 - 8 6.8 12.5 9.3 6.5 12.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Zip PF02535.22 ORY37056.1 - 8.8 5.4 6.8 9.4 5.3 6.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Mpp10 PF04006.12 ORY37056.1 - 9.8 4.5 24.9 11 4.4 24.9 1.0 1 0 0 1 1 1 0 Mpp10 protein Ribonuclease_3 PF00636.26 ORY37058.1 - 3.9e-40 136.7 0.0 1.3e-20 74.0 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 ORY37058.1 - 3.7e-24 85.3 0.0 1e-08 35.4 0.0 3.6 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 ORY37058.1 - 2.1e-16 59.8 0.0 5.5e-16 58.5 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 ORY37058.1 - 3.6e-15 56.3 0.0 1.3e-14 54.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY37058.1 - 0.001 19.1 0.0 0.0036 17.3 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY37058.1 - 0.042 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase DUF1624 PF07786.12 ORY37060.1 - 1.1e-09 38.3 20.6 2.1e-09 37.3 18.2 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1624) SHR3_chaperone PF08229.11 ORY37060.1 - 0.71 8.8 10.8 1.4 7.9 1.0 2.9 2 1 1 3 3 3 0 ER membrane protein SH3 DUF1624 PF07786.12 ORY37061.1 - 9.5e-08 31.9 13.5 9.5e-08 31.9 13.5 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1624) Acyl_transf_3 PF01757.22 ORY37061.1 - 7.1e-06 25.3 39.2 1.4e-05 24.3 39.2 1.5 1 1 0 1 1 1 1 Acyltransferase family DUF872 PF05915.12 ORY37063.1 - 0.074 13.2 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Phosphoesterase PF04185.14 ORY37063.1 - 0.095 11.9 0.1 0.11 11.7 0.1 1.1 1 0 0 1 1 1 0 Phosphoesterase family Cut8 PF08559.10 ORY37065.1 - 0.008 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein IGPD PF00475.18 ORY37066.1 - 2.3e-52 177.2 1.9 5.5e-52 175.9 1.9 1.6 1 1 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Acetyltransf_3 PF13302.7 ORY37068.1 - 0.0019 18.9 0.0 0.02 15.5 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY37068.1 - 0.13 12.2 0.0 1.4 8.9 0.0 2.3 1 1 0 1 1 1 0 FR47-like protein Peptidase_M64 PF09471.10 ORY37069.1 - 4.7e-29 101.7 0.0 2.2e-28 99.5 0.0 1.9 1 1 0 1 1 1 1 IgA Peptidase M64 Peptidase_S9 PF00326.21 ORY37070.1 - 2.5e-35 121.9 0.0 4e-35 121.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ORY37070.1 - 9e-10 38.6 0.0 4.7e-08 33.0 0.0 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 ORY37070.1 - 4.8e-08 33.0 0.0 4.5e-07 29.8 0.0 2.2 1 1 0 1 1 1 1 Putative esterase DLH PF01738.18 ORY37070.1 - 3.2e-07 30.1 0.0 1.4e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.12 ORY37070.1 - 7.5e-05 21.6 0.0 0.00035 19.4 0.0 1.9 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 ORY37070.1 - 8.7e-05 22.1 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_1 PF00561.20 ORY37070.1 - 0.00044 20.0 0.0 0.0013 18.5 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY37070.1 - 0.0017 19.0 0.0 0.003 18.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 ORY37070.1 - 0.0051 15.7 0.0 0.014 14.3 0.0 1.6 3 0 0 3 3 3 1 Carboxylesterase family Peptidase_S28 PF05577.12 ORY37070.1 - 0.022 13.6 0.0 0.039 12.7 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 BAAT_C PF08840.11 ORY37070.1 - 0.029 14.3 0.0 0.056 13.4 0.0 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 ORY37070.1 - 0.041 13.7 0.0 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S10 PF00450.22 ORY37070.1 - 0.1 12.0 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 Serine carboxypeptidase eRF1_1 PF03463.15 ORY37071.1 - 1.9e-48 163.7 0.2 3e-48 163.1 0.2 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 ORY37071.1 - 1.2e-26 93.6 0.1 1.9e-26 93.0 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 ORY37071.1 - 6.3e-25 87.9 0.0 1.9e-24 86.3 0.0 1.8 2 0 0 2 2 2 1 eRF1 domain 3 EF-hand_3 PF09069.11 ORY37071.1 - 0.11 12.9 0.4 0.38 11.2 0.1 2.1 2 0 0 2 2 2 0 EF-hand IBN_N PF03810.19 ORY37075.1 - 3.2e-14 52.6 0.1 8.9e-13 48.0 0.0 3.0 2 1 1 3 3 3 1 Importin-beta N-terminal domain DUF1624 PF07786.12 ORY37075.1 - 4.5e-10 39.5 0.9 6.9e-09 35.6 1.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1624) DUF5009 PF16401.5 ORY37075.1 - 1.2e-05 24.9 2.7 9e-05 22.1 2.6 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF5009) HPP PF04982.13 ORY37076.1 - 9.6e-40 135.6 6.3 9.6e-40 135.6 6.3 1.7 2 0 0 2 2 2 1 HPP family Trypsin_2 PF13365.6 ORY37077.1 - 4.3e-30 105.6 0.1 6.6e-30 105.0 0.1 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 ORY37077.1 - 1.1e-11 45.0 0.1 1.9e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 ORY37077.1 - 9.2e-09 35.0 0.1 1.6e-07 31.1 0.0 2.4 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 ORY37077.1 - 2e-08 34.4 0.0 1e-07 32.2 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 ORY37077.1 - 4.3e-07 30.2 0.0 2.2e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 ORY37077.1 - 0.0017 17.1 0.2 0.56 8.8 0.0 2.1 2 0 0 2 2 2 2 Peptidase S46 Peptidase_S29 PF02907.15 ORY37077.1 - 0.0031 17.3 0.1 0.0082 15.9 0.0 1.7 2 0 0 2 2 2 1 Hepatitis C virus NS3 protease Peptidase_S32 PF05579.13 ORY37077.1 - 0.14 11.4 1.6 0.95 8.6 0.1 2.3 3 0 0 3 3 3 0 Equine arteritis virus serine endopeptidase S32 Cluap1 PF10234.9 ORY37079.1 - 1.1e-101 339.7 7.9 1.1e-101 339.7 7.9 1.5 2 0 0 2 2 2 1 Clusterin-associated protein-1 FtsX_ECD PF18075.1 ORY37079.1 - 0.0011 19.5 2.3 0.14 12.8 0.4 2.6 2 0 0 2 2 2 2 FtsX extracellular domain Fez1 PF06818.15 ORY37079.1 - 0.0041 17.6 11.5 0.0041 17.6 11.5 1.8 1 1 1 2 2 2 1 Fez1 Ndc80_HEC PF03801.13 ORY37079.1 - 0.021 14.5 0.1 0.057 13.0 0.1 1.8 1 1 0 1 1 1 0 HEC/Ndc80p family Lectin_N PF03954.14 ORY37079.1 - 0.022 14.5 6.1 0.45 10.3 0.2 2.5 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Laminin_II PF06009.12 ORY37079.1 - 0.15 12.1 4.2 0.24 11.4 0.4 2.4 2 0 0 2 2 2 0 Laminin Domain II Tweety PF04906.13 ORY37079.1 - 0.65 8.6 4.9 1.5 7.4 0.3 2.3 1 1 1 2 2 2 0 Tweety ATP-synt_DE PF00401.20 ORY37079.1 - 1.2 9.4 4.6 3.9 7.8 0.3 2.5 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain LRR_8 PF13855.6 ORY37080.1 - 9.4e-20 70.1 59.3 4.5e-07 29.5 2.7 11.1 6 2 7 15 15 15 9 Leucine rich repeat LRR_4 PF12799.7 ORY37080.1 - 5.4e-15 55.3 59.9 5.3e-07 29.9 1.8 11.3 6 4 6 13 13 13 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY37080.1 - 2.6e-05 24.1 42.5 2.5 9.0 0.1 15.2 19 1 0 19 19 19 3 Leucine Rich Repeat LRR_6 PF13516.6 ORY37080.1 - 0.00042 20.1 31.6 3.6 7.9 0.1 11.4 13 0 0 13 13 13 3 Leucine Rich repeat RNA_pol_Rpc4 PF05132.14 ORY37082.1 - 2.8e-18 66.8 21.9 6.3e-18 65.6 0.0 4.0 2 2 1 3 3 3 2 RNA polymerase III RPC4 DUF4603 PF15376.6 ORY37082.1 - 1.6 6.0 7.5 0.85 6.9 5.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4603) Ank_2 PF12796.7 ORY37083.1 - 0.027 15.1 0.0 0.045 14.3 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) RINGv PF12906.7 ORY37084.1 - 0.00047 20.2 4.0 0.00098 19.2 4.0 1.5 1 0 0 1 1 1 1 RING-variant domain YiiD_C PF09500.10 ORY37084.1 - 0.12 12.3 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Putative thioesterase (yiiD_Cterm) DUF832 PF05734.11 ORY37084.1 - 0.19 11.2 0.7 0.52 9.8 0.1 1.9 2 0 0 2 2 2 0 Herpesvirus protein of unknown function (DUF832) Nnf1 PF03980.14 ORY37086.1 - 3.9e-11 43.3 1.5 1.3e-10 41.6 1.5 1.8 1 1 0 1 1 1 1 Nnf1 APG6_N PF17675.1 ORY37086.1 - 0.023 15.2 1.1 0.032 14.7 1.1 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region GAS PF13851.6 ORY37086.1 - 0.04 13.3 4.2 0.032 13.6 2.5 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 ORY37086.1 - 0.062 13.7 3.5 0.12 12.8 3.5 1.5 1 0 0 1 1 1 0 Cell division protein ZapB MSC PF09402.10 ORY37086.1 - 0.099 12.1 0.3 0.13 11.7 0.3 1.2 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain HSP90 PF00183.18 ORY37087.1 - 1.1e-182 608.6 16.4 1.3e-182 608.3 16.4 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 ORY37087.1 - 5.9e-12 46.1 0.1 1e-11 45.3 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORY37087.1 - 1.8e-11 44.0 0.3 5.3e-11 42.5 0.3 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3549 PF12069.8 ORY37087.1 - 0.02 13.9 0.1 0.037 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3549) Glyco_hydro_1 PF00232.18 ORY37090.1 - 2.4e-84 283.4 0.6 2.8e-84 283.1 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DUF4097 PF13349.6 ORY37091.1 - 1.7e-07 30.9 8.7 2.6e-07 30.2 8.7 1.3 1 0 0 1 1 1 1 Putative adhesin RNA_pol_RpbG PF16992.5 ORY37091.1 - 0.17 12.0 0.0 1.3 9.1 0.0 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase, subunit G DUF4097 PF13349.6 ORY37092.1 - 3.6e-07 29.8 0.1 4.2e-07 29.6 0.1 1.1 1 0 0 1 1 1 1 Putative adhesin PNP_UDP_1 PF01048.20 ORY37094.1 - 1.9e-31 109.1 0.1 2.4e-31 108.8 0.1 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily PNP_UDP_1 PF01048.20 ORY37095.1 - 7e-32 110.6 0.1 9.1e-32 110.2 0.1 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily TauD PF02668.16 ORY37096.1 - 4e-52 177.6 0.3 5.3e-52 177.3 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fasciclin PF02469.22 ORY37097.1 - 3.1e-37 127.7 7.7 4.3e-22 78.7 3.3 2.1 2 0 0 2 2 2 2 Fasciclin domain Glyco_hydro_18 PF00704.28 ORY37098.1 - 4.1e-60 204.1 3.7 5.1e-60 203.8 3.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LRR_8 PF13855.6 ORY37099.1 - 5.2e-15 55.0 13.7 4.4e-08 32.8 2.1 3.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY37099.1 - 7.6e-13 48.4 20.7 8.8e-06 26.0 3.0 5.6 4 2 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY37099.1 - 1.6e-06 27.8 17.0 2.5 9.0 0.1 7.8 9 0 0 9 9 9 3 Leucine Rich Repeat F-box PF00646.33 ORY37099.1 - 0.028 14.3 0.5 0.27 11.2 0.2 2.6 2 0 0 2 2 2 0 F-box domain Nrap_D5 PF17406.2 ORY37100.1 - 1.4e-43 148.5 0.7 1.6e-42 145.1 0.4 2.4 2 0 0 2 2 2 1 Nrap protein PAP/OAS1-like domain 5 Nrap PF03813.14 ORY37100.1 - 1.6e-42 145.2 0.0 3.1e-42 144.2 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D2 PF17403.2 ORY37100.1 - 4e-41 140.3 1.6 3.7e-40 137.2 0.5 2.7 2 1 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D4 PF17405.2 ORY37100.1 - 2.2e-37 128.5 0.0 4.3e-37 127.5 0.0 1.5 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D3 PF17404.2 ORY37100.1 - 7.6e-34 117.1 0.2 1.7e-33 115.9 0.0 1.7 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap_D6 PF17407.2 ORY37100.1 - 5.9e-28 97.8 0.2 1.6e-27 96.3 0.2 1.8 1 0 0 1 1 1 1 Nrap protein domain 6 RPN7 PF10602.9 ORY37100.1 - 0.042 13.6 0.2 0.1 12.3 0.2 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN7 FIN1 PF17300.2 ORY37100.1 - 0.12 11.8 4.9 0.22 11.0 4.9 1.3 1 0 0 1 1 1 0 Filaments in between nuclei protein-1 Merozoite_SPAM PF07133.11 ORY37100.1 - 0.42 10.6 20.2 0.85 9.6 20.2 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) SDA1 PF05285.12 ORY37100.1 - 2.5 7.5 12.1 3.5 6.9 12.1 1.2 1 0 0 1 1 1 0 SDA1 FtsJ PF01728.19 ORY37101.1 - 1.4e-70 237.0 0.0 1.7e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase WD40 PF00400.32 ORY37102.1 - 8.1e-126 406.3 57.9 5.7e-11 42.8 0.8 12.9 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY37102.1 - 2.9e-42 142.8 12.1 0.00089 19.5 0.1 12.5 1 1 11 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY37102.1 - 2.1e-24 86.1 15.9 0.042 12.5 0.0 11.5 4 3 8 12 12 12 10 Nucleoporin Nup120/160 eIF2A PF08662.11 ORY37102.1 - 1.2e-15 57.9 5.8 0.00083 19.3 0.2 5.4 1 1 4 5 5 5 4 Eukaryotic translation initiation factor eIF2A TIR_2 PF13676.6 ORY37102.1 - 1.7e-12 47.9 0.1 6.2e-12 46.2 0.0 2.1 2 0 0 2 2 2 1 TIR domain WD40_like PF17005.5 ORY37102.1 - 2.1e-12 47.0 9.8 0.87 8.9 0.0 8.8 4 3 6 10 10 10 6 WD40-like domain Ge1_WD40 PF16529.5 ORY37102.1 - 3.2e-10 39.5 25.5 0.28 10.1 0.8 11.1 1 1 6 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 ORY37102.1 - 1e-06 28.8 0.1 7.8e-06 25.9 0.1 2.3 1 1 0 1 1 1 1 NACHT domain TIR PF01582.20 ORY37102.1 - 0.00055 19.8 0.4 0.0033 17.2 0.0 2.2 2 0 0 2 2 2 1 TIR domain AAA_16 PF13191.6 ORY37102.1 - 0.00057 20.3 0.0 0.0013 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Polysacc_synt_2 PF02719.15 ORY37102.1 - 0.0011 18.1 1.6 1.2 8.3 0.0 3.7 4 0 0 4 4 4 1 Polysaccharide biosynthesis protein nos_propeller PF18764.1 ORY37102.1 - 0.0099 15.8 0.3 7.3 6.6 0.0 4.8 5 0 0 5 5 5 1 Nitrous oxide reductase propeller repeat Plavaka PF18759.1 ORY37102.1 - 0.01 15.1 0.0 18 4.4 0.0 4.1 1 1 3 5 5 5 0 Plavaka transposase RecQ_Zn_bind PF16124.5 ORY37102.1 - 0.057 14.2 0.0 0.16 12.7 0.0 1.7 1 0 0 1 1 1 0 RecQ zinc-binding Nuc_deoxyrib_tr PF05014.15 ORY37102.1 - 0.063 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase AAA_30 PF13604.6 ORY37102.1 - 0.066 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AHJR-like PF18743.1 ORY37102.1 - 0.084 12.4 1.0 30 4.2 0.0 3.3 3 0 0 3 3 3 0 REase_AHJR-like Rav1p_C PF12234.8 ORY37104.1 - 1.2e-150 503.0 4.1 5.2e-150 500.9 3.3 2.3 2 1 0 2 2 2 1 RAVE protein 1 C terminal WD40 PF00400.32 ORY37104.1 - 0.00095 19.9 16.0 0.31 12.0 0.0 7.1 8 0 0 8 8 8 2 WD domain, G-beta repeat DUF5522 PF17653.1 ORY37105.1 - 9.8e-19 67.1 9.9 2e-18 66.1 9.9 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5522) Peripla_BP_2 PF01497.18 ORY37105.1 - 2.7e-06 27.1 0.0 4.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein Diphthami_syn_2 PF01902.17 ORY37105.1 - 4.9e-06 26.2 0.0 8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Diphthamide synthase Radical_SAM PF04055.21 ORY37105.1 - 0.11 12.9 0.0 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 Radical SAM superfamily tRNA-synt_2d PF01409.20 ORY37106.1 - 5.8e-90 301.0 0.0 9.1e-90 300.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 ORY37106.1 - 1.1e-16 60.8 0.1 1.1e-16 60.8 0.1 2.1 3 0 0 3 3 3 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 ORY37106.1 - 1.4e-09 37.8 0.0 1.2e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2b PF00587.25 ORY37106.1 - 1.8e-05 24.8 0.0 3.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 ORY37106.1 - 0.0035 16.5 0.5 0.018 14.2 0.1 2.3 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) PheRS_DBD1 PF18552.1 ORY37106.1 - 0.03 14.1 0.0 0.076 12.8 0.0 1.8 1 0 0 1 1 1 0 PheRS DNA binding domain 1 S10_plectin PF03501.15 ORY37106.1 - 0.14 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 Plectin/S10 domain ABC_membrane PF00664.23 ORY37107.1 - 5.5e-60 203.3 34.2 4.4e-32 111.8 12.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY37107.1 - 2e-56 190.3 0.0 2e-32 112.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY37107.1 - 2e-11 43.7 4.4 0.0045 16.4 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY37107.1 - 1.6e-08 34.6 0.8 0.0034 17.4 0.1 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY37107.1 - 7.6e-08 32.0 0.5 0.012 15.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY37107.1 - 7e-07 29.8 0.2 0.029 14.8 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 ORY37107.1 - 8.1e-07 29.2 1.4 0.0018 18.4 0.7 2.6 2 0 0 2 2 2 2 Dynamin family AAA_21 PF13304.6 ORY37107.1 - 1.1e-06 28.7 0.5 0.11 12.3 0.0 3.8 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORY37107.1 - 3.3e-06 27.1 1.3 0.0023 17.9 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 ORY37107.1 - 1.8e-05 25.4 0.4 0.15 12.5 0.2 2.3 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 ORY37107.1 - 0.00017 21.0 0.4 0.38 10.1 0.0 2.2 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF87 PF01935.17 ORY37107.1 - 0.00031 20.9 3.5 0.063 13.4 0.1 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 ORY37107.1 - 0.00047 19.2 0.1 0.73 8.7 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.6 ORY37107.1 - 0.0014 18.9 1.0 1.5 9.1 0.1 2.9 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 ORY37107.1 - 0.0015 18.5 0.4 3.1 7.7 0.0 3.0 2 0 0 2 2 2 2 NACHT domain T2SSE PF00437.20 ORY37107.1 - 0.0016 17.6 0.0 0.31 10.1 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 ORY37107.1 - 0.0021 17.6 0.1 2.4 7.7 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region NB-ARC PF00931.22 ORY37107.1 - 0.0022 17.2 1.0 1.4 8.1 0.1 2.4 2 0 0 2 2 2 2 NB-ARC domain cobW PF02492.19 ORY37107.1 - 0.0023 17.5 1.0 0.23 11.1 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 ORY37107.1 - 0.0026 17.6 0.1 0.83 9.3 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 ORY37107.1 - 0.0038 17.0 0.3 2.1 8.0 0.1 2.9 3 0 0 3 3 3 1 AAA domain KAP_NTPase PF07693.14 ORY37107.1 - 0.0042 16.4 0.1 0.31 10.2 0.1 2.3 2 0 0 2 2 2 1 KAP family P-loop domain Zeta_toxin PF06414.12 ORY37107.1 - 0.01 15.1 0.2 0.76 9.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin DUF815 PF05673.13 ORY37107.1 - 0.019 14.2 0.1 2.4 7.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Roc PF08477.13 ORY37107.1 - 0.021 15.0 0.3 3.6 7.8 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Pox_A32 PF04665.12 ORY37107.1 - 0.084 12.3 0.3 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AIG1 PF04548.16 ORY37107.1 - 0.24 10.7 2.6 2.6 7.3 0.3 2.3 2 0 0 2 2 2 0 AIG1 family OPT PF03169.15 ORY37108.1 - 7.4e-125 417.9 48.8 8.7e-125 417.7 48.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2109 PF09882.9 ORY37108.1 - 0.91 9.6 10.2 0.34 10.9 1.0 3.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2109) KH_8 PF17903.1 ORY37109.1 - 4.5e-31 106.8 0.0 8.6e-31 105.9 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 ORY37109.1 - 0.013 15.3 0.0 0.033 14.0 0.0 1.7 1 1 1 2 2 2 0 KH domain Dscam_C PF12355.8 ORY37109.1 - 0.021 15.8 0.5 0.043 14.8 0.5 1.5 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal UTP25 PF06862.12 ORY37110.1 - 1.9e-172 574.3 1.9 4.6e-160 533.5 0.1 2.1 2 0 0 2 2 2 2 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 ORY37110.1 - 0.00036 20.3 0.1 0.66 9.7 0.0 2.4 2 1 0 2 2 2 2 DEAD/DEAH box helicase TFIIA PF03153.13 ORY37110.1 - 0.00063 19.9 21.9 0.00088 19.4 21.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SAPS PF04499.15 ORY37110.1 - 3 6.5 11.9 5.2 5.7 11.9 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNA_pol_3_Rpc31 PF11705.8 ORY37110.1 - 6.5 6.9 39.9 18 5.5 39.9 1.8 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Lipase_GDSL_2 PF13472.6 ORY37112.1 - 3.1e-21 76.6 0.0 5e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY37112.1 - 1e-09 38.7 0.0 1.6e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase zf-C2H2 PF00096.26 ORY37113.1 - 1.3e-06 28.6 7.1 0.0046 17.3 1.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY37113.1 - 1.8e-06 28.3 7.5 0.0021 18.8 1.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-LYAR PF08790.11 ORY37113.1 - 0.015 15.2 1.4 0.16 11.9 0.3 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_6 PF13912.6 ORY37113.1 - 0.025 14.6 6.7 0.12 12.4 1.4 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY37113.1 - 0.03 14.6 3.2 3.2 8.2 2.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY37113.1 - 0.1 13.0 4.4 0.2 12.1 1.9 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type SOAR PF16533.5 ORY37114.1 - 0.029 14.3 5.1 0.045 13.7 5.1 1.2 1 0 0 1 1 1 0 STIM1 Orai1-activating region Orthopox_F8 PF05886.11 ORY37114.1 - 0.51 10.5 3.0 0.99 9.6 3.0 1.7 1 1 0 1 1 1 0 Orthopoxvirus F8 protein LNS2 PF08235.13 ORY37116.1 - 3.7e-91 304.6 0.1 1.1e-89 299.8 0.1 2.1 1 1 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_mid PF16876.5 ORY37116.1 - 3.6e-11 43.1 0.0 2e-10 40.7 0.0 2.2 2 0 0 2 2 2 1 Lipin/Ned1/Smp2 multi-domain protein middle domain Lipin_N PF04571.14 ORY37116.1 - 0.0014 18.6 0.7 0.0034 17.3 0.0 2.1 2 0 0 2 2 2 1 lipin, N-terminal conserved region Sgf11 PF08209.11 ORY37176.1 - 0.00029 20.3 0.1 0.00044 19.8 0.1 1.2 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf_C2HC_14 PF18574.1 ORY37176.1 - 0.015 15.1 0.4 0.021 14.6 0.4 1.2 1 0 0 1 1 1 0 C2HC Zing finger domain DUF4674 PF15719.5 ORY37176.1 - 0.027 14.5 0.2 0.027 14.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) zf_C2H2_13 PF18508.1 ORY37176.1 - 0.051 13.2 1.1 0.084 12.5 1.1 1.3 1 0 0 1 1 1 0 Zinc finger domain LtrA PF06772.11 ORY37181.1 - 1.9e-25 89.9 28.5 1.7e-24 86.7 28.5 2.0 1 1 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF5090 PF17009.5 ORY37182.1 - 0.015 15.3 0.5 0.024 14.6 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) zf-HC5HC2H_2 PF13832.6 ORY37183.1 - 6.3e-27 93.9 1.8 6.3e-27 93.9 1.8 1.8 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 ORY37183.1 - 8.8e-15 54.7 2.5 8.8e-15 54.7 2.5 2.7 2 1 0 2 2 2 1 PHD-like zinc-binding domain SOCS_box PF07525.16 ORY37183.1 - 0.065 13.6 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 SOCS box IBV_3B PF03622.13 ORY37183.1 - 0.093 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 IBV 3B protein OrfB_Zn_ribbon PF07282.11 ORY37183.1 - 0.099 12.6 0.3 0.099 12.6 0.3 1.7 2 0 0 2 2 2 0 Putative transposase DNA-binding domain PyrI_C PF02748.15 ORY37184.1 - 0.054 13.4 0.6 2.1 8.3 0.1 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Elf1 PF05129.13 ORY37184.1 - 0.16 12.1 4.6 21 5.2 0.1 3.3 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like BOP1NT PF08145.12 ORY37186.1 - 4.1e-95 318.6 9.0 7.5e-95 317.8 9.0 1.4 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 ORY37186.1 - 1e-22 80.0 8.7 7e-09 36.2 0.4 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY37186.1 - 7.7e-07 29.3 0.2 0.012 15.9 0.1 4.3 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF3g PF12353.8 ORY37186.1 - 0.17 12.3 0.1 0.44 10.9 0.0 1.6 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Gcd10p PF04189.13 ORY37187.1 - 2.5e-64 217.3 0.1 3.1e-64 217.0 0.1 1.1 1 0 0 1 1 1 1 Gcd10p family Atg14 PF10186.9 ORY37187.1 - 0.13 11.4 1.7 0.19 10.8 1.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TRM PF02005.16 ORY37188.1 - 0.14 11.3 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase F-box_4 PF15966.5 ORY37190.1 - 0.00041 20.2 0.3 0.00085 19.2 0.1 1.7 2 0 0 2 2 2 1 F-box F-box-like PF12937.7 ORY37190.1 - 0.0061 16.4 0.2 0.023 14.6 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORY37192.1 - 0.017 15.0 0.2 0.04 13.8 0.0 1.7 2 0 0 2 2 2 0 F-box F-box-like PF12937.7 ORY37193.1 - 3.9e-05 23.4 1.8 0.00035 20.4 0.4 2.7 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 ORY37193.1 - 0.00045 20.1 0.0 0.0015 18.4 0.0 1.9 2 0 0 2 2 2 1 F-box NAC PF01849.18 ORY37194.1 - 2.7e-08 33.6 3.6 4e-07 29.9 2.1 2.8 2 1 0 2 2 2 1 NAC domain Halogen_Hydrol PF10112.9 ORY37194.1 - 0.38 10.8 4.8 31 4.5 0.2 3.0 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein LZ_Tnp_IS66 PF13007.7 ORY37194.1 - 3.1 8.6 6.0 0.82 10.5 2.0 2.0 2 1 0 2 2 2 0 Transposase C of IS166 homeodomain Dynamin_M PF01031.20 ORY37195.1 - 2.3e-93 312.5 0.0 5.6e-93 311.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 ORY37195.1 - 2.6e-56 190.3 0.0 5e-56 189.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 ORY37195.1 - 2.6e-26 91.6 3.9 2.6e-26 91.6 3.9 1.7 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 ORY37195.1 - 0.0002 21.4 0.4 0.0022 18.0 0.4 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY37195.1 - 0.031 14.7 0.0 0.099 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 ORY37195.1 - 0.15 12.3 0.0 1.5 9.0 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 ORY37195.1 - 1.9 8.1 5.5 1.6 8.4 0.1 2.4 3 0 0 3 3 3 0 AAA ATPase domain zf-C2H2 PF00096.26 ORY37196.1 - 1.4e-11 44.1 24.0 0.00096 19.5 3.6 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY37196.1 - 5.1e-11 42.5 16.1 0.0006 20.1 0.2 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY37196.1 - 1.3e-10 41.2 24.0 0.0072 17.1 0.5 4.5 4 1 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY37196.1 - 8.2e-06 25.7 18.4 1.2e-05 25.1 0.5 4.3 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORY37196.1 - 8.4e-05 22.2 15.2 0.13 12.0 1.0 4.2 4 0 0 4 4 4 3 zinc-finger C2H2-type zf-met PF12874.7 ORY37196.1 - 0.0038 17.6 14.8 0.025 15.0 1.4 3.9 4 0 0 4 4 4 1 Zinc-finger of C2H2 type Zn_ribbon_SprT PF17283.2 ORY37196.1 - 0.0045 16.9 0.5 0.0045 16.9 0.5 3.3 3 0 0 3 3 3 1 SprT-like zinc ribbon domain zf-C2H2_8 PF15909.5 ORY37196.1 - 0.018 15.4 5.5 0.063 13.6 0.9 2.3 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 ORY37196.1 - 0.02 15.2 12.6 6.9 7.1 0.8 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DUF629 PF04780.12 ORY37196.1 - 0.021 13.4 0.0 0.021 13.4 0.0 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF629) zf_C2H2_ZHX PF18387.1 ORY37196.1 - 0.024 14.2 0.5 0.024 14.2 0.5 3.7 2 1 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF4379 PF14311.6 ORY37196.1 - 0.038 14.4 7.1 4 7.9 0.1 3.1 3 0 0 3 3 3 0 Probable Zinc-ribbon domain C1_4 PF07975.12 ORY37196.1 - 0.41 10.9 13.1 1.3 9.3 2.1 3.7 2 1 2 4 4 4 0 TFIIH C1-like domain zf-C2HE PF16278.5 ORY37196.1 - 0.94 10.0 12.9 1.3 9.5 4.6 3.5 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Coiled PF05710.12 ORY37196.1 - 1.3 9.8 4.5 0.4 11.5 1.1 1.9 1 1 1 2 2 2 0 Coiled coil CpXC PF14353.6 ORY37196.1 - 2.3 8.3 10.0 4.3 7.4 0.2 3.5 3 1 0 3 3 3 0 CpXC protein zf-C2H2_3rep PF18868.1 ORY37196.1 - 3.9 8.2 10.2 4.4 8.0 3.1 3.1 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats HalOD2 PF18547.1 ORY37196.1 - 4.9 7.1 14.6 6.9 6.7 1.0 3.7 3 1 0 3 3 3 0 Halobacterial output domain 2 Ribosomal_S8e PF01201.22 ORY37197.1 - 2.3e-56 189.7 2.5 2.7e-56 189.5 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e DUF2087 PF09860.9 ORY37198.1 - 0.025 14.7 0.2 0.31 11.2 0.2 2.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) F-box_4 PF15966.5 ORY37200.1 - 0.035 14.0 0.1 0.066 13.1 0.1 1.5 1 0 0 1 1 1 0 F-box F-box_4 PF15966.5 ORY37201.1 - 0.014 15.2 0.0 0.042 13.7 0.0 2.0 1 0 0 1 1 1 0 F-box zf-H2C2_2 PF13465.6 ORY37202.1 - 2.8e-13 49.6 4.0 1.4e-05 25.3 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY37202.1 - 4.7e-11 42.5 15.1 0.001 19.4 1.2 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY37202.1 - 1e-06 29.0 14.0 0.0035 18.1 0.9 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORY37202.1 - 5.9e-05 22.7 8.8 0.15 11.9 1.0 3.5 3 0 0 3 3 3 3 C2H2-type zinc-finger domain zf-C2H2_8 PF15909.5 ORY37202.1 - 0.0091 16.3 6.8 0.0095 16.2 3.7 2.1 1 1 1 2 2 2 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 ORY37202.1 - 0.021 15.5 2.8 0.027 15.1 0.4 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain Glyco_hydro_64 PF16483.5 ORY37202.1 - 0.036 13.3 0.0 0.04 13.2 0.0 1.1 1 0 0 1 1 1 0 Beta-1,3-glucanase zf-C2H2_jaz PF12171.8 ORY37202.1 - 0.043 14.1 0.5 0.26 11.6 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY37202.1 - 0.074 13.1 0.3 0.074 13.1 0.3 3.4 4 0 0 4 4 3 0 C2H2-type zinc finger zf-C2HE PF16278.5 ORY37202.1 - 0.074 13.5 7.2 0.18 12.2 0.1 3.0 4 0 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger C1_4 PF07975.12 ORY37202.1 - 0.11 12.7 2.4 0.22 11.8 2.4 1.6 1 1 0 1 1 1 0 TFIIH C1-like domain DEAD PF00270.29 ORY37203.1 - 2.4e-16 60.0 0.0 3.2e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ORY37203.1 - 1.5e-05 25.3 0.1 2.9e-05 24.4 0.1 1.4 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 ORY37203.1 - 3.1e-05 23.9 0.0 4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Helicase AAA_30 PF13604.6 ORY37203.1 - 0.00023 20.9 0.1 0.00033 20.4 0.1 1.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 ORY37203.1 - 0.00035 20.6 0.0 0.00049 20.1 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 ORY37203.1 - 0.0005 19.8 0.0 0.00062 19.5 0.0 1.1 1 0 0 1 1 1 1 SWI2/SNF2 ATPase PhoH PF02562.16 ORY37203.1 - 0.064 12.7 0.1 0.52 9.7 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 ORY37203.1 - 0.097 12.2 0.6 0.35 10.4 0.6 1.9 1 1 0 1 1 1 0 AAA domain Helicase_C PF00271.31 ORY37204.1 - 1.5e-10 41.4 0.0 2.1e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2188 PF09954.9 ORY37205.1 - 0.14 12.3 0.1 0.42 10.8 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) CRM1_C PF08767.11 ORY37206.1 - 9.2e-113 376.6 9.5 9.2e-113 376.6 9.5 3.7 3 1 0 3 3 3 2 CRM1 C terminal Xpo1 PF08389.12 ORY37206.1 - 6.8e-44 149.5 9.3 1.8e-43 148.1 7.4 2.9 2 0 0 2 2 2 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 ORY37206.1 - 5.3e-34 115.7 5.3 1.7e-33 114.1 5.3 2.0 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 ORY37206.1 - 3e-28 97.7 3.0 5.1e-28 96.9 1.0 2.5 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 ORY37206.1 - 3.3e-19 68.1 1.3 1e-18 66.5 1.3 1.9 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 ORY37206.1 - 1.2e-13 50.7 0.5 5.5e-13 48.6 0.1 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Syd PF07348.12 ORY37206.1 - 0.0046 16.6 0.2 0.015 15.0 0.2 1.8 1 0 0 1 1 1 1 Syd protein (SUKH-2) BID PF06393.11 ORY37206.1 - 0.014 14.9 0.1 0.058 12.9 0.0 2.1 2 0 0 2 2 2 0 BH3 interacting domain (BID) WD40_alt PF14077.6 ORY37206.1 - 2.3 8.2 4.9 2.8 7.9 0.1 3.1 3 0 0 3 3 3 0 Alternative WD40 repeat motif MFS_1 PF07690.16 ORY37207.1 - 3.4e-32 111.8 60.5 5.2e-22 78.2 35.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY37207.1 - 0.002 16.8 44.2 0.042 12.4 25.1 2.8 1 1 1 2 2 2 2 MFS/sugar transport protein EamA PF00892.20 ORY37207.1 - 0.023 14.9 9.5 0.023 14.9 9.5 4.4 4 2 0 4 4 4 0 EamA-like transporter family TPR_12 PF13424.6 ORY37208.1 - 7.1e-62 205.7 22.4 5.7e-18 65.0 0.2 6.0 2 1 5 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 ORY37208.1 - 1.3e-43 145.7 8.3 2e-09 37.0 0.0 9.1 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_7 PF13176.6 ORY37208.1 - 3.5e-19 67.3 7.1 0.018 15.0 0.0 8.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 ORY37208.1 - 1.1e-14 53.5 10.8 0.31 10.9 0.0 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY37208.1 - 1.7e-13 49.5 12.9 0.27 11.5 0.3 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 ORY37208.1 - 3.6e-11 42.9 0.9 3.8 8.6 0.0 7.8 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY37208.1 - 2.9e-10 39.5 15.7 0.076 13.3 0.0 8.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY37208.1 - 1.3e-09 37.9 6.3 2.1e-05 24.1 1.9 3.1 2 1 1 3 3 3 2 MalT-like TPR region TPR_16 PF13432.6 ORY37208.1 - 4.7e-09 36.8 5.8 1.7 9.4 0.0 7.9 6 2 1 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY37208.1 - 4.2e-07 30.2 5.4 6.6 7.6 0.1 7.5 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_4 PF07721.14 ORY37208.1 - 2.7e-06 27.5 0.0 5.4 7.9 0.0 5.4 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY37208.1 - 3.1e-06 27.6 11.2 0.099 13.2 0.0 6.4 3 2 4 8 8 7 2 Tetratricopeptide repeat TPR_5 PF12688.7 ORY37208.1 - 0.00029 21.1 0.5 0.42 10.9 0.1 3.5 2 1 1 3 3 3 1 Tetratrico peptide repeat RPN7 PF10602.9 ORY37208.1 - 0.00088 19.0 0.8 0.2 11.4 0.0 4.1 3 1 0 4 4 4 1 26S proteasome subunit RPN7 TPR_17 PF13431.6 ORY37208.1 - 0.023 15.1 14.8 9.4 6.9 0.1 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat RPN6_N PF18055.1 ORY37208.1 - 0.036 14.4 0.2 1.3 9.4 0.1 3.3 2 1 1 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain PPR PF01535.20 ORY37208.1 - 0.053 13.8 8.9 16 6.0 0.0 6.1 8 0 0 8 8 6 0 PPR repeat RTP1_C1 PF10363.9 ORY37208.1 - 0.15 12.2 0.0 0.47 10.6 0.0 1.8 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 MIT PF04212.18 ORY37208.1 - 0.17 12.0 2.1 21 5.3 0.1 3.8 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 ORY37208.1 - 0.38 11.2 2.8 3.7 8.0 0.1 3.3 3 2 1 4 4 4 0 Bacterial transcriptional activator domain LRR_8 PF13855.6 ORY37209.1 - 7.8e-19 67.2 24.9 3.3e-07 30.0 6.5 4.1 2 2 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 ORY37209.1 - 6.8e-12 45.4 19.7 0.0019 18.6 0.5 5.2 2 2 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY37209.1 - 1.4e-06 28.0 20.0 0.11 13.1 0.4 7.7 8 0 0 8 8 8 3 Leucine Rich Repeat DUF4097 PF13349.6 ORY37210.1 - 5.6e-05 22.6 2.1 8.6e-05 22.0 2.0 1.3 1 1 0 1 1 1 1 Putative adhesin SusE PF14292.6 ORY37210.1 - 0.025 14.8 6.6 0.044 14.0 6.6 1.5 1 1 0 1 1 1 0 SusE outer membrane protein LsmAD PF06741.13 ORY37211.1 - 1.1e-24 86.8 1.9 2e-24 85.9 1.9 1.5 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 ORY37211.1 - 8e-12 45.1 0.0 1.5e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain PhoLip_ATPase_C PF16212.5 ORY37212.1 - 1.9e-49 168.7 19.5 1.9e-49 168.7 19.5 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY37212.1 - 7.8e-16 57.5 5.3 1.6e-15 56.5 5.3 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 ORY37212.1 - 8.6e-12 45.8 0.1 0.00011 22.6 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORY37212.1 - 1e-11 44.7 0.0 4.6e-11 42.6 0.0 2.1 1 1 1 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 ORY37212.1 - 6.6e-08 32.5 0.0 4.4e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY37212.1 - 0.0026 17.6 0.1 0.005 16.6 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Glycos_transf_1 PF00534.20 ORY37213.1 - 2.6e-08 33.6 0.0 1.2e-07 31.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY37213.1 - 0.00013 22.4 0.0 0.00026 21.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 UIM PF02809.20 ORY37213.1 - 0.31 11.1 3.3 5.6 7.1 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin interaction motif Macro PF01661.21 ORY37214.1 - 4e-29 101.1 0.0 7.5e-29 100.2 0.0 1.5 1 0 0 1 1 1 1 Macro domain Ribosomal_S17_N PF16205.5 ORY37214.1 - 0.17 12.3 0.0 0.41 11.1 0.0 1.6 1 0 0 1 1 1 0 Ribosomal_S17 N-terminal PHO4 PF01384.20 ORY37215.1 - 9.8e-114 379.9 24.0 1.4e-113 379.4 24.0 1.2 1 0 0 1 1 1 1 Phosphate transporter family Bacteriocin_IIi PF11758.8 ORY37215.1 - 0.019 14.8 0.5 0.052 13.4 0.5 1.7 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin Dpy19 PF10034.9 ORY37215.1 - 0.069 11.3 3.5 0.11 10.7 3.5 1.2 1 0 0 1 1 1 0 Q-cell neuroblast polarisation DUF4017 PF13209.6 ORY37215.1 - 2.6 8.0 8.2 0.18 11.8 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4017) dCache_1 PF02743.18 ORY37217.1 - 1.7e-15 57.5 0.5 2.5e-15 56.9 0.5 1.3 1 0 0 1 1 1 1 Cache domain dCache_1 PF02743.18 ORY37218.1 - 1.7e-12 47.6 2.1 4.5e-12 46.3 1.8 1.9 1 1 1 2 2 2 1 Cache domain DUF5344 PF17279.2 ORY37218.1 - 0.14 12.8 0.2 0.4 11.3 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5344) CodY PF06018.14 ORY37218.1 - 0.16 11.5 0.2 6.6 6.2 0.0 2.2 2 0 0 2 2 2 0 CodY GAF-like domain Chorismate_synt PF01264.21 ORY37219.1 - 6.3e-136 452.4 0.0 7.3e-136 452.2 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Cdd1 PF11731.8 ORY37219.1 - 0.073 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Pathogenicity locus Ras PF00071.22 ORY37220.1 - 1.2e-20 73.8 0.0 2e-20 73.0 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 ORY37220.1 - 6.4e-16 58.6 0.0 1e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY37220.1 - 0.021 14.3 0.0 0.029 13.8 0.0 1.2 1 0 0 1 1 1 0 ADP-ribosylation factor family ATP_bind_1 PF03029.17 ORY37220.1 - 0.096 12.4 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein WD40 PF00400.32 ORY37225.1 - 1.6e-14 54.1 19.8 0.011 16.6 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat Gpi16 PF04113.14 ORY37226.1 - 4.1e-131 438.2 0.0 2.6e-130 435.5 0.0 1.8 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Ribonuc_L-PSP PF01042.21 ORY37227.1 - 1e-28 99.8 0.0 1.4e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP P_proprotein PF01483.20 ORY37227.1 - 0.074 13.1 0.1 0.14 12.2 0.1 1.6 1 1 0 1 1 1 0 Proprotein convertase P-domain pPIWI_RE_REase PF18154.1 ORY37227.1 - 0.085 12.8 0.0 2.5 8.1 0.0 2.3 1 1 1 2 2 2 0 REase associating with pPIWI_RE F-box-like PF12937.7 ORY37228.1 - 0.00022 21.0 1.8 0.32 10.9 0.1 2.6 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 ORY37228.1 - 0.003 17.4 10.0 0.0091 15.9 0.4 3.4 3 0 0 3 3 3 2 F-box domain PRANC PF09372.10 ORY37228.1 - 0.0088 16.3 0.9 0.41 11.0 0.1 2.6 2 0 0 2 2 2 1 PRANC domain F-box_4 PF15966.5 ORY37228.1 - 0.088 12.7 1.0 14 5.6 0.1 2.9 3 0 0 3 3 3 0 F-box Plavaka PF18759.1 ORY37229.1 - 3.1e-42 144.9 0.0 4.2e-42 144.5 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase NCE101 PF11654.8 ORY37229.1 - 0.03 14.0 0.0 0.092 12.5 0.0 1.8 1 0 0 1 1 1 0 Non-classical export protein 1 FAD_syn PF06574.12 ORY37231.1 - 6.8e-07 29.3 0.0 2.9e-06 27.2 0.1 1.9 2 0 0 2 2 2 1 FAD synthetase CTP_transf_like PF01467.26 ORY37231.1 - 8.7e-07 29.2 0.0 1.3e-06 28.6 0.0 1.5 1 1 0 1 1 1 1 Cytidylyltransferase-like PT-TG PF14449.6 ORY37231.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Pre-toxin TG Sacchrp_dh_C PF16653.5 ORY37232.1 - 1.1e-95 320.7 0.0 2.6e-95 319.5 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 ORY37232.1 - 4.7e-25 88.3 0.4 9.6e-25 87.3 0.4 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 ORY37232.1 - 1.7e-06 28.1 0.9 2.5e-06 27.5 0.3 1.6 2 0 0 2 2 2 1 NAD(P)H-binding Shikimate_DH PF01488.20 ORY37232.1 - 0.0019 18.3 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.16 ORY37232.1 - 0.017 15.7 0.1 0.034 14.8 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ORY37232.1 - 0.018 15.6 0.4 0.098 13.3 0.1 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 ORY37232.1 - 0.12 13.2 0.1 0.21 12.4 0.1 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Peripla_BP_4 PF13407.6 ORY37232.1 - 0.2 11.2 1.0 2.5 7.6 0.3 2.6 3 0 0 3 3 3 0 Periplasmic binding protein domain Steroid_dh PF02544.16 ORY37233.1 - 1e-40 139.2 0.6 1.8e-40 138.3 0.6 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase YukD PF08817.10 ORY37233.1 - 0.006 17.3 0.0 0.011 16.4 0.0 1.4 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD PEMT PF04191.13 ORY37233.1 - 0.031 14.7 1.3 0.082 13.3 0.2 2.2 2 0 0 2 2 2 0 Phospholipid methyltransferase ubiquitin PF00240.23 ORY37233.1 - 0.05 13.4 0.1 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin family PhoLip_ATPase_C PF16212.5 ORY37234.1 - 4.5e-79 265.7 25.3 4.5e-79 265.7 25.3 2.8 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY37234.1 - 8.1e-26 89.5 1.4 2.8e-25 87.8 1.4 2.0 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 ORY37234.1 - 3.9e-11 42.9 0.0 1.4e-10 41.2 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 ORY37234.1 - 3.8e-09 36.3 0.0 9.9e-09 35.0 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 ORY37234.1 - 9.5e-09 35.8 2.8 0.00068 20.0 0.0 4.0 4 1 1 5 5 5 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORY37234.1 - 0.0038 17.0 0.2 0.011 15.5 0.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Usp PF00582.26 ORY37236.1 - 3.6e-11 43.7 0.0 3.6e-11 43.7 0.0 4.4 3 2 1 4 4 4 1 Universal stress protein family Apolipoprotein PF01442.18 ORY37236.1 - 0.0011 18.9 5.9 0.0011 18.9 5.9 8.6 2 1 5 8 8 8 4 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 ORY37236.1 - 0.004 17.2 3.6 0.004 17.2 3.6 5.9 5 2 1 6 6 6 1 Apolipophorin-III precursor (apoLp-III) Crystall_4 PF17945.1 ORY37236.1 - 0.013 15.9 0.2 14 6.2 0.0 3.1 2 0 0 2 2 2 0 Beta/Gamma crystallin pP_pnuc_2 PF18166.1 ORY37236.1 - 0.092 12.8 1.6 3.5 7.7 0.1 3.2 2 0 0 2 2 2 0 Predicted pPIWI-associating nuclease Baculo_PEP_C PF04513.12 ORY37236.1 - 1.5 8.9 47.4 0.16 12.0 0.3 10.5 6 3 7 13 13 13 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2564 PF10819.8 ORY37236.1 - 5.5 7.4 10.2 2 8.9 1.6 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2564) 7tm_3 PF00003.22 ORY37238.1 - 2e-23 83.4 9.7 3.4e-23 82.6 9.7 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR AveC_like PF17198.4 ORY37238.1 - 0.056 12.9 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Spirocyclase AveC-like Lectin_N PF03954.14 ORY37238.1 - 0.065 13.0 0.0 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain EGF PF00008.27 ORY37238.1 - 1 9.8 4.4 2.5 8.5 4.4 1.7 1 0 0 1 1 1 0 EGF-like domain YesK PF14150.6 ORY37238.1 - 5.4 7.3 10.6 5.7 7.2 0.8 3.5 2 1 1 3 3 3 0 YesK-like protein Usp PF00582.26 ORY37239.1 - 1.1e-21 77.9 0.0 1.6e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Anoctamin PF04547.12 ORY37240.1 - 3.2e-71 240.5 20.0 6.8e-71 239.4 20.0 1.5 1 1 0 1 1 1 1 Calcium-activated chloride channel DUF104 PF01954.16 ORY37240.1 - 0.019 15.4 0.4 0.05 14.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF104 dCache_1 PF02743.18 ORY37242.1 - 2.4e-10 40.6 2.8 1.1e-09 38.4 2.4 2.3 1 1 0 1 1 1 1 Cache domain OEP PF02321.18 ORY37242.1 - 0.042 13.7 0.9 3.5 7.4 0.1 2.3 2 0 0 2 2 2 0 Outer membrane efflux protein Wound_ind PF08186.11 ORY37243.1 - 0.11 13.0 0.1 0.18 12.3 0.1 1.4 1 0 0 1 1 1 0 Wound-inducible basic protein family Anoctamin PF04547.12 ORY37244.1 - 9.2e-80 268.7 7.6 1.1e-79 268.4 7.6 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Pilin_PilX PF11530.8 ORY37244.1 - 0.093 12.7 0.2 0.37 10.7 0.2 1.9 1 1 0 1 1 1 0 Minor type IV pilin, PilX DUF588 PF04535.12 ORY37244.1 - 0.11 12.3 2.0 0.25 11.1 2.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF588) DUF3180 PF11377.8 ORY37244.1 - 0.4 10.8 7.9 0.09 12.9 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) UQ_con PF00179.26 ORY37246.1 - 2.9e-43 146.9 0.2 3.3e-43 146.7 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY37246.1 - 0.0011 18.7 0.0 0.0018 18.0 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 ORY37246.1 - 0.027 14.8 0.0 0.028 14.7 0.0 1.3 1 0 0 1 1 1 0 RWD domain BUD22 PF09073.10 ORY37247.1 - 0.043 13.2 20.8 0.068 12.5 20.8 1.3 1 0 0 1 1 1 0 BUD22 Pyridoxal_deC PF00282.19 ORY37249.1 - 6.6e-05 21.8 0.0 8.5e-05 21.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF4920 PF16267.5 ORY37249.1 - 0.038 14.0 0.3 0.056 13.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4920) Methyltransf_16 PF10294.9 ORY37250.1 - 3.4e-33 114.8 0.0 9.2e-33 113.4 0.0 1.6 1 1 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 ORY37250.1 - 0.02 14.6 0.0 0.03 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 ORY37250.1 - 0.043 13.4 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain KH_1 PF00013.29 ORY37251.1 - 1.2e-89 294.1 48.5 8.3e-13 48.0 0.4 15.0 14 1 0 14 14 14 12 KH domain KH_2 PF07650.17 ORY37251.1 - 1.6e-06 27.8 25.1 0.46 10.3 0.5 9.4 8 2 1 9 9 9 2 KH domain KH_4 PF13083.6 ORY37251.1 - 3.7e-05 23.5 3.8 0.63 10.0 0.1 5.6 5 0 0 5 5 5 1 KH domain SLS PF14611.6 ORY37251.1 - 0.033 14.0 13.9 0.5 10.2 0.4 6.1 5 2 2 7 7 7 0 Mitochondrial inner-membrane-bound regulator BMC PF00936.19 ORY37251.1 - 0.24 11.4 15.7 8.3 6.5 0.1 5.4 5 0 0 5 5 5 0 BMC domain RHH_1 PF01402.21 ORY37251.1 - 2.3 8.3 4.4 54 3.9 0.1 3.5 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family tRNA-synt_1g PF09334.11 ORY37253.1 - 0.12 11.1 2.5 0.16 10.7 2.5 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) Glyco_hydro_18 PF00704.28 ORY37254.1 - 9.2e-42 143.9 0.9 2.3e-41 142.6 0.9 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF1910 PF08928.10 ORY37256.1 - 0.051 13.6 1.0 0.19 11.8 1.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) Pkinase PF00069.25 ORY37257.1 - 1.2e-59 201.8 0.0 1.4e-59 201.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY37257.1 - 4.3e-33 114.7 0.0 5.3e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY37257.1 - 5.8e-07 29.1 0.0 7.9e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY37257.1 - 9.4e-05 22.4 2.6 0.26 11.2 2.9 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY37257.1 - 0.00034 19.7 0.0 0.00047 19.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 ORY37257.1 - 0.0057 16.3 0.2 0.013 15.1 0.0 1.5 2 0 0 2 2 2 1 RIO1 family Seadorna_VP7 PF07387.11 ORY37257.1 - 0.015 14.4 0.1 0.024 13.7 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 ORY37257.1 - 0.015 14.6 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_C PF00433.24 ORY37257.1 - 0.089 13.5 0.0 0.2 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.11 ORY37257.1 - 0.097 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cyclin_N PF00134.23 ORY37258.1 - 4.4e-12 45.9 0.2 8.1e-12 45.0 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORY37258.1 - 0.0017 18.5 0.2 0.0036 17.4 0.0 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain MULE PF10551.9 ORY37259.1 - 1.2e-08 35.2 0.1 3.2e-08 33.9 0.1 1.8 1 0 0 1 1 1 1 MULE transposase domain FAR1 PF03101.15 ORY37259.1 - 0.029 15.1 0.2 0.029 15.1 0.2 2.6 2 0 0 2 2 2 0 FAR1 DNA-binding domain Torsin PF06309.11 ORY37259.1 - 0.11 12.6 0.3 2.6 8.2 0.0 3.2 4 0 0 4 4 4 0 Torsin AAA_14 PF13173.6 ORY37260.1 - 0.0034 17.4 0.3 0.1 12.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 ORY37260.1 - 0.0036 17.6 0.0 0.04 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY37260.1 - 0.17 12.2 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain TPX2_importin PF12214.8 ORY37261.1 - 5.5e-14 52.7 6.6 5.5e-14 52.7 6.6 6.5 6 2 1 8 8 8 1 Cell cycle regulated microtubule associated protein TPX2 PF06886.11 ORY37261.1 - 8.4e-11 41.9 20.1 8.4e-11 41.9 20.1 5.3 6 0 0 6 6 6 1 Targeting protein for Xklp2 (TPX2) CEP63 PF17045.5 ORY37262.1 - 0.0041 17.1 1.7 0.0061 16.5 1.7 1.2 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa BRE1 PF08647.11 ORY37262.1 - 0.0099 15.9 11.5 0.015 15.4 11.5 1.2 1 0 0 1 1 1 1 BRE1 E3 ubiquitin ligase DUF1053 PF06327.14 ORY37262.1 - 0.013 16.0 0.4 0.019 15.5 0.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) DUF3450 PF11932.8 ORY37262.1 - 0.014 14.8 1.8 0.02 14.2 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FapA PF03961.13 ORY37262.1 - 0.016 13.8 0.2 0.019 13.6 0.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A GIT_CC PF16559.5 ORY37262.1 - 0.03 14.2 1.2 0.078 12.9 0.1 2.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Seryl_tRNA_N PF02403.22 ORY37262.1 - 0.041 14.1 4.9 0.041 14.1 4.9 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CASP_C PF08172.12 ORY37262.1 - 0.11 11.8 4.9 0.19 11.0 0.7 2.0 1 1 1 2 2 2 0 CASP C terminal JIP_LZII PF16471.5 ORY37262.1 - 0.16 12.1 6.3 0.1 12.8 4.1 1.7 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DivIC PF04977.15 ORY37262.1 - 0.55 10.0 9.6 0.16 11.8 3.0 2.2 1 1 1 2 2 2 0 Septum formation initiator FlaC_arch PF05377.11 ORY37262.1 - 0.92 9.9 5.6 3.1 8.2 0.8 2.4 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) YabA PF06156.13 ORY37262.1 - 0.95 10.1 6.3 2 9.1 6.3 1.5 1 1 0 1 1 1 0 Initiation control protein YabA DUF2312 PF10073.9 ORY37262.1 - 0.96 9.1 5.7 4.7 6.9 0.5 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) ZapB PF06005.12 ORY37262.1 - 1.1 9.8 11.5 4.8 7.7 11.6 1.9 1 1 0 1 1 1 0 Cell division protein ZapB XhlA PF10779.9 ORY37262.1 - 1.2 9.4 8.3 0.68 10.2 1.5 2.2 1 1 1 2 2 2 0 Haemolysin XhlA DUF16 PF01519.16 ORY37262.1 - 2.2 8.8 6.6 9.6 6.8 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 bZIP_1 PF00170.21 ORY37262.1 - 4.7 7.4 11.7 8.7 6.5 1.6 2.6 1 1 1 2 2 2 0 bZIP transcription factor APG6_N PF17675.1 ORY37262.1 - 5.7 7.5 11.8 14 6.2 11.8 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region Acyltransferase PF01553.21 ORY37263.1 - 1.7e-12 47.1 0.0 3.4e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 ORY37263.1 - 0.00047 20.2 0.5 0.43 10.7 0.1 2.3 2 0 0 2 2 2 2 Acyltransferase C-terminus TMEM40 PF15817.5 ORY37263.1 - 0.088 12.6 0.4 0.17 11.7 0.4 1.4 1 0 0 1 1 1 0 Transmembrane protein 40 family Acyltransferase PF01553.21 ORY37264.1 - 2.1e-11 43.6 0.4 8.7e-09 35.1 0.3 2.8 2 1 0 2 2 2 1 Acyltransferase Acyltransf_C PF16076.5 ORY37264.1 - 4.3e-06 26.7 2.5 8.6e-05 22.6 2.5 2.4 1 1 0 1 1 1 1 Acyltransferase C-terminus DUF2892 PF11127.8 ORY37266.1 - 0.079 13.0 0.6 0.079 13.0 0.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2892) Acyltransferase PF01553.21 ORY37267.1 - 2.7e-12 46.5 0.7 1.4e-11 44.2 0.0 2.1 2 0 0 2 2 2 1 Acyltransferase Acyltransf_C PF16076.5 ORY37267.1 - 2.6e-05 24.2 2.6 0.00029 20.9 2.6 2.2 1 1 0 1 1 1 1 Acyltransferase C-terminus ThrE PF06738.12 ORY37267.1 - 0.11 11.9 0.5 0.16 11.3 0.5 1.2 1 0 0 1 1 1 0 Putative threonine/serine exporter PRiA4_ORF3 PF07929.11 ORY37267.1 - 0.11 12.1 0.1 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein Pkinase PF00069.25 ORY37268.1 - 4.6e-76 255.7 0.0 5.8e-76 255.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY37268.1 - 4.2e-38 131.1 0.0 5.6e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY37268.1 - 2.3e-06 26.8 0.3 3.8e-06 26.1 0.3 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY37268.1 - 1.5e-05 25.0 2.3 0.0014 18.6 0.2 2.5 3 0 0 3 3 3 2 Phosphotransferase enzyme family RIO1 PF01163.22 ORY37268.1 - 1.8e-05 24.4 0.1 3.1e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 ORY37268.1 - 2.3e-05 23.9 0.1 3.9e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY37268.1 - 3.7e-05 23.2 0.0 8.4e-05 22.0 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 ORY37268.1 - 0.00033 19.8 0.4 0.00071 18.7 0.1 1.6 2 0 0 2 2 2 1 Seadornavirus VP7 YukC PF10140.9 ORY37268.1 - 0.003 16.5 0.4 0.0043 15.9 0.4 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC YrbL-PhoP_reg PF10707.9 ORY37268.1 - 0.012 15.1 0.1 0.024 14.1 0.1 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.20 ORY37268.1 - 0.052 13.1 1.1 0.11 12.1 1.1 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase DSBA PF01323.20 ORY37269.1 - 1.6e-46 158.5 0.0 1.9e-25 89.8 0.0 2.1 2 0 0 2 2 2 2 DSBA-like thioredoxin domain NOP5NT PF08156.13 ORY37271.1 - 0.11 12.9 0.9 9 6.8 0.1 2.6 2 1 0 2 2 2 0 NOP5NT (NUC127) domain PIF1 PF05970.14 ORY37272.1 - 1.1e-11 44.6 0.1 1.4e-11 44.2 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase SH3_13 PF18335.1 ORY37272.1 - 2e-05 24.3 0.0 3.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain LANC_like PF05147.13 ORY37272.1 - 0.018 13.6 0.0 0.022 13.3 0.0 1.1 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein Hydrophobin PF01185.18 ORY37272.1 - 0.022 15.4 0.4 0.034 14.8 0.4 1.2 1 0 0 1 1 1 0 Fungal hydrophobin zf-HYPF PF07503.12 ORY37273.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 HypF finger zf_C2H2_13 PF18508.1 ORY37274.1 - 0.0028 17.2 0.1 0.0044 16.6 0.1 1.3 1 0 0 1 1 1 1 Zinc finger domain Sgf11 PF08209.11 ORY37274.1 - 0.0069 15.9 0.0 0.0093 15.5 0.0 1.2 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) DUF4674 PF15719.5 ORY37274.1 - 0.014 15.4 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) zf_UBZ PF18439.1 ORY37274.1 - 0.07 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger OrsD PF12013.8 ORY37274.1 - 0.12 12.8 1.1 0.26 11.7 1.1 1.6 1 1 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D Homeodomain PF00046.29 ORY37275.1 - 5.2e-19 67.8 4.0 7e-19 67.4 3.1 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 ORY37275.1 - 0.036 14.0 0.3 0.036 14.0 0.3 2.4 2 0 0 2 2 2 0 Homeobox KN domain Glutaredoxin PF00462.24 ORY37276.1 - 2.2e-20 72.6 0.0 3.3e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin SH3BGR PF04908.15 ORY37276.1 - 0.1 12.8 0.0 0.16 12.1 0.0 1.5 1 1 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Mg_trans_NIPA PF05653.14 ORY37278.1 - 2.6e-05 23.5 8.6 3.1e-05 23.2 8.6 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA Ank_2 PF12796.7 ORY37280.1 - 6.1e-28 97.2 5.9 5.8e-14 52.5 0.2 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) FYVE PF01363.21 ORY37280.1 - 1.1e-17 63.9 7.6 1.1e-17 63.9 7.6 2.2 2 0 0 2 2 2 1 FYVE zinc finger Ank_4 PF13637.6 ORY37280.1 - 8.5e-15 54.9 2.4 9.4e-09 35.6 0.1 4.8 2 1 3 5 5 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY37280.1 - 4e-13 49.3 2.3 3.8e-07 30.2 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY37280.1 - 2.9e-12 45.6 0.5 0.0015 18.9 0.0 5.4 4 1 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 ORY37280.1 - 7e-10 38.9 1.6 0.013 15.9 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat zf-RING_2 PF13639.6 ORY37280.1 - 3.3e-07 30.5 2.5 3.3e-07 30.5 2.5 4.0 4 0 0 4 4 4 1 Ring finger domain Pex24p PF06398.11 ORY37280.1 - 0.0002 20.5 0.0 0.0003 19.9 0.0 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin UBZ_FAAP20 PF15750.5 ORY37280.1 - 0.0011 18.8 3.1 0.014 15.3 0.8 2.7 2 0 0 2 2 2 1 Ubiquitin-binding zinc-finger zf-C3HC4_2 PF13923.6 ORY37280.1 - 0.0082 16.0 2.0 0.0082 16.0 2.0 4.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY37280.1 - 0.0095 16.2 1.7 0.0095 16.2 1.7 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain Ribosomal_60s PF00428.19 ORY37280.1 - 0.013 16.1 2.1 0.061 13.9 2.1 2.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-RING_11 PF17123.5 ORY37280.1 - 0.014 15.1 2.5 0.014 15.1 2.5 2.2 2 0 0 2 2 2 0 RING-like zinc finger E7 PF00527.18 ORY37280.1 - 0.047 13.9 4.2 0.12 12.6 1.0 2.8 3 0 0 3 3 2 0 E7 protein, Early protein Atracotoxin PF05353.11 ORY37280.1 - 0.14 12.2 1.9 0.29 11.2 1.9 1.5 1 0 0 1 1 1 0 Delta Atracotoxin FANCL_C PF11793.8 ORY37280.1 - 0.68 10.1 5.4 0.53 10.5 2.2 2.4 2 0 0 2 2 2 0 FANCL C-terminal domain FYVE_2 PF02318.16 ORY37280.1 - 2 8.6 8.5 0.31 11.3 3.6 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger Myosin_head PF00063.21 ORY37281.1 - 3.1e-250 832.1 5.6 3.1e-250 832.1 5.6 2.3 2 0 0 2 2 2 2 Myosin head (motor domain) DIL PF01843.19 ORY37281.1 - 8.8e-19 67.7 0.2 2.7e-18 66.2 0.2 1.9 1 0 0 1 1 1 1 DIL domain IQ PF00612.27 ORY37281.1 - 3.8e-09 35.5 9.9 5.9e-06 25.6 2.6 4.0 3 0 0 3 3 3 2 IQ calmodulin-binding motif AAA_22 PF13401.6 ORY37281.1 - 0.014 15.7 0.0 0.081 13.2 0.0 2.4 1 0 0 1 1 1 0 AAA domain Csm4_C PF17953.1 ORY37281.1 - 0.02 14.8 0.0 0.052 13.4 0.0 1.7 1 0 0 1 1 1 0 CRISPR Csm4 C-terminal domain AAA_16 PF13191.6 ORY37281.1 - 0.029 14.8 0.6 0.26 11.7 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain PI3K_P85_iSH2 PF16454.5 ORY37281.1 - 0.035 13.7 6.0 0.094 12.3 6.0 1.7 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain MbeD_MobD PF04899.12 ORY37281.1 - 0.12 12.5 0.5 0.47 10.6 0.2 2.2 1 1 1 2 2 2 0 MbeD/MobD like YabA PF06156.13 ORY37281.1 - 0.76 10.5 3.9 0.32 11.6 0.3 2.3 2 0 0 2 2 2 0 Initiation control protein YabA HALZ PF02183.18 ORY37281.1 - 2.6 8.3 4.8 1 9.6 0.8 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF2087 PF09860.9 ORY37282.1 - 3.5e-08 33.5 0.0 8e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2087) HTH_1 PF00126.27 ORY37282.1 - 0.098 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family zf-H2C2_2 PF13465.6 ORY37283.1 - 5.5e-10 39.2 17.2 8.9e-05 22.7 0.5 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY37283.1 - 5.5e-08 32.8 19.5 3.2e-05 24.1 2.2 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY37283.1 - 0.00038 21.1 17.4 0.0036 18.0 1.8 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORY37283.1 - 0.002 18.3 5.1 0.043 14.0 0.1 2.0 1 1 1 2 2 2 2 Aberrant zinc-finger Lact-deh-memb PF09330.11 ORY37283.1 - 0.023 14.1 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding FOXP-CC PF16159.5 ORY37283.1 - 0.073 13.7 2.6 2.3 8.9 0.4 2.1 2 0 0 2 2 2 0 FOXP coiled-coil domain CHORD PF04968.12 ORY37283.1 - 0.29 11.9 8.0 6.6 7.5 4.9 2.1 2 0 0 2 2 2 0 CHORD zf-C2H2_6 PF13912.6 ORY37283.1 - 2.4 8.2 12.8 5.4 7.1 1.6 3.6 3 2 0 3 3 3 0 C2H2-type zinc finger ATG16 PF08614.11 ORY37284.1 - 8.9e-07 29.3 136.1 0.012 15.9 13.7 8.5 2 1 5 7 7 7 5 Autophagy protein 16 (ATG16) PACT_coil_coil PF10495.9 ORY37284.1 - 7.5e-05 23.2 9.2 0.00015 22.3 0.0 4.8 4 0 0 4 4 4 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein GAS PF13851.6 ORY37284.1 - 0.0008 18.8 5.8 0.0008 18.8 5.8 8.6 3 2 5 8 8 8 4 Growth-arrest specific micro-tubule binding Filament PF00038.21 ORY37284.1 - 0.0048 16.5 6.4 0.0048 16.5 6.4 9.2 2 2 4 7 7 7 4 Intermediate filament protein APG6_N PF17675.1 ORY37284.1 - 0.0083 16.7 14.6 0.0083 16.7 14.6 9.5 3 2 6 9 9 9 2 Apg6 coiled-coil region GAIN_A PF18619.1 ORY37284.1 - 0.15 12.3 6.6 22 5.3 0.2 4.7 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A DUF1192 PF06698.11 ORY37284.1 - 0.37 10.9 21.1 1.1 9.4 0.4 8.3 8 1 0 8 8 8 0 Protein of unknown function (DUF1192) TPR_MLP1_2 PF07926.12 ORY37284.1 - 3.5 7.7 123.5 0.013 15.6 15.9 10.9 3 2 4 9 9 9 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.9 ORY37284.1 - 6.6 6.8 134.3 0.15 12.1 5.7 10.5 4 2 4 9 9 9 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PBP_like_2 PF12849.7 ORY37286.1 - 0.00039 20.2 0.6 0.00047 19.9 0.6 1.0 1 0 0 1 1 1 1 PBP superfamily domain Myosin_head PF00063.21 ORY37287.1 - 1.8e-247 822.9 4.5 2.7e-247 822.4 4.5 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 ORY37287.1 - 3.5e-21 75.4 0.9 3.1e-20 72.4 0.0 2.8 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 ORY37287.1 - 5.9e-11 41.2 10.5 1.6e-06 27.4 2.0 4.5 4 0 0 4 4 4 2 IQ calmodulin-binding motif MAD PF05557.13 ORY37287.1 - 1.5e-05 23.6 7.0 1.5e-05 23.6 7.0 1.8 2 0 0 2 2 2 1 Mitotic checkpoint protein DUF4201 PF13870.6 ORY37287.1 - 8e-05 22.4 6.7 8e-05 22.4 6.7 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) Spc7 PF08317.11 ORY37287.1 - 0.00062 18.8 9.2 0.00062 18.8 9.2 1.9 2 0 0 2 2 2 1 Spc7 kinetochore protein AAA_22 PF13401.6 ORY37287.1 - 0.0076 16.5 0.0 0.033 14.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY37287.1 - 0.032 14.6 0.0 0.12 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain Csm4_C PF17953.1 ORY37287.1 - 0.085 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 CRISPR Csm4 C-terminal domain Tropomyosin_1 PF12718.7 ORY37287.1 - 0.097 12.8 10.1 0.3 11.2 10.1 1.8 1 0 0 1 1 1 0 Tropomyosin like ERM PF00769.19 ORY37287.1 - 0.33 10.7 17.6 0.74 9.6 17.6 1.6 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Laminin_I PF06008.14 ORY37287.1 - 0.75 9.5 16.4 0.018 14.7 9.5 1.7 2 0 0 2 2 2 0 Laminin Domain I DUF724 PF05266.14 ORY37287.1 - 8.1 6.2 8.9 19 5.0 8.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF16 PF01519.16 ORY37288.1 - 0.00077 19.9 3.9 0.0013 19.1 3.9 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF16 TMF_DNA_bd PF12329.8 ORY37288.1 - 0.0012 18.7 4.6 0.0021 18.0 3.7 1.8 1 1 0 1 1 1 1 TATA element modulatory factor 1 DNA binding DASH_Spc19 PF08287.11 ORY37288.1 - 0.0015 18.4 6.2 0.0021 18.0 6.2 1.2 1 0 0 1 1 1 1 Spc19 Spc7 PF08317.11 ORY37288.1 - 0.003 16.5 6.2 0.0035 16.3 6.2 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Filament PF00038.21 ORY37288.1 - 0.0083 15.8 8.4 0.01 15.4 8.4 1.1 1 0 0 1 1 1 1 Intermediate filament protein Atg14 PF10186.9 ORY37288.1 - 0.0092 15.1 4.2 0.01 14.9 4.2 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 ORY37288.1 - 0.0094 15.3 7.3 0.011 15.1 7.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) GrpE PF01025.19 ORY37288.1 - 0.011 15.4 5.2 0.013 15.1 5.2 1.2 1 0 0 1 1 1 0 GrpE Mt_ATP-synt_D PF05873.12 ORY37288.1 - 0.012 15.5 1.4 0.016 15.1 1.4 1.3 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) Bcr-Abl_Oligo PF09036.10 ORY37288.1 - 0.017 15.1 1.4 0.027 14.5 1.4 1.3 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain APG6_N PF17675.1 ORY37288.1 - 0.017 15.6 9.0 0.022 15.3 9.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region TEX13 PF15186.6 ORY37288.1 - 0.024 14.3 7.3 0.031 14.0 7.3 1.1 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family SlyX PF04102.12 ORY37288.1 - 0.027 15.1 16.4 0.13 12.8 12.5 2.4 2 0 0 2 2 2 0 SlyX DUF724 PF05266.14 ORY37288.1 - 0.03 14.2 5.9 0.043 13.7 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) VPS38 PF17649.1 ORY37288.1 - 0.036 13.0 0.6 0.04 12.8 0.6 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 38 ADIP PF11559.8 ORY37288.1 - 0.081 13.0 14.2 0.19 11.8 14.4 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3138 PF11336.8 ORY37288.1 - 0.1 11.2 4.1 0.1 11.2 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Spc29 PF17082.5 ORY37288.1 - 0.11 12.3 4.0 0.17 11.7 4.0 1.5 1 1 0 1 1 1 0 Spindle Pole Component 29 Spc24 PF08286.11 ORY37288.1 - 0.19 12.0 3.2 0.37 11.0 3.2 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 YlqD PF11068.8 ORY37288.1 - 0.2 12.0 10.7 0.28 11.5 10.7 1.2 1 0 0 1 1 1 0 YlqD protein FlaC_arch PF05377.11 ORY37288.1 - 0.24 11.8 4.1 0.52 10.7 4.1 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Herpes_UL6 PF01763.16 ORY37288.1 - 0.3 9.6 4.6 0.41 9.1 4.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like MIP-T3_C PF17749.1 ORY37288.1 - 0.62 10.0 11.0 0.1 12.5 5.4 2.0 1 1 1 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region FlxA PF14282.6 ORY37288.1 - 2.8 8.0 21.9 9.5 6.3 17.4 2.4 1 1 1 2 2 2 0 FlxA-like protein DivIC PF04977.15 ORY37288.1 - 5 7.0 15.0 14 5.5 15.0 1.8 1 1 0 1 1 1 0 Septum formation initiator ABC_tran_CTD PF16326.5 ORY37288.1 - 8.6 6.7 21.5 2.4e+02 2.1 21.5 2.4 1 1 0 1 1 1 0 ABC transporter C-terminal domain Myosin_head PF00063.21 ORY37289.1 - 1e-241 803.9 0.2 1.5e-241 803.3 0.2 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 ORY37289.1 - 2e-07 30.2 11.5 0.00048 19.7 0.8 3.9 4 0 0 4 4 4 2 IQ calmodulin-binding motif TMF_TATA_bd PF12325.8 ORY37289.1 - 0.013 15.7 3.4 0.013 15.7 3.4 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding AAA_16 PF13191.6 ORY37289.1 - 0.065 13.6 0.0 0.065 13.6 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain FlaC_arch PF05377.11 ORY37289.1 - 2 8.8 8.0 3.8 8.0 0.9 3.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Asp PF00026.23 ORY37293.1 - 7.2e-51 173.5 1.5 1.6e-50 172.4 1.5 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY37293.1 - 2.8e-10 40.7 0.7 3.1e-08 34.1 0.2 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY37293.1 - 6.8e-08 32.4 0.0 1.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 ORY37293.1 - 0.00013 22.5 0.1 0.23 12.1 0.0 3.2 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 ORY37293.1 - 0.0028 18.2 0.2 0.43 11.2 0.1 3.7 2 2 0 2 2 2 1 gag-polyprotein putative aspartyl protease HNH_2 PF13391.6 ORY37295.1 - 7.3e-09 35.6 0.8 2.8e-08 33.8 0.8 2.0 1 1 0 1 1 1 1 HNH endonuclease SPRY PF00622.28 ORY37296.1 - 6.4e-15 55.3 0.3 4.8e-10 39.6 0.1 3.4 3 0 0 3 3 3 3 SPRY domain F-box PF00646.33 ORY37296.1 - 0.011 15.6 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 ORY37296.1 - 0.011 15.6 0.1 0.024 14.5 0.1 1.6 1 0 0 1 1 1 0 F-box-like TMEM174 PF15029.6 ORY37296.1 - 0.45 10.2 3.0 3.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 174 Asp PF00026.23 ORY37297.1 - 1.3e-46 159.5 1.2 1.7e-46 159.1 1.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY37297.1 - 7.6e-12 45.8 0.1 9.5e-06 26.0 0.1 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY37297.1 - 1.3e-05 25.1 0.0 2.1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal ADK PF00406.22 ORY37298.1 - 5.2e-45 153.2 0.0 6.7e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ORY37298.1 - 1.5e-30 106.4 0.0 2.1e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY37298.1 - 6.7e-06 26.7 0.0 1.3e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY37298.1 - 0.0053 16.9 0.0 0.017 15.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 ORY37298.1 - 0.016 14.9 0.1 4.5 6.9 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase Pex26 PF07163.12 ORY37299.1 - 0.09 12.1 1.5 0.1 11.9 1.5 1.1 1 0 0 1 1 1 0 Pex26 protein DUF747 PF05346.11 ORY37376.1 - 5.1e-109 364.6 8.4 7.5e-109 364.1 8.4 1.3 1 0 0 1 1 1 1 Eukaryotic membrane protein family ACOX PF01756.19 ORY37378.1 - 4.9e-49 166.3 0.0 8.6e-49 165.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 ORY37378.1 - 1.8e-21 77.0 0.0 3.8e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 ORY37378.1 - 1.5e-13 50.8 0.0 2.8e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ORY37378.1 - 0.081 13.1 0.0 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY37378.1 - 0.093 13.4 0.0 0.45 11.2 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain Homeodomain PF00046.29 ORY37379.1 - 3e-13 49.4 1.8 8.7e-13 47.9 1.8 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY37379.1 - 1.2e-05 25.1 0.1 3.8e-05 23.5 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain Glyco_transf_20 PF00982.21 ORY37380.1 - 5.3e-184 612.3 0.0 6.6e-184 612.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 ORY37380.1 - 1.2e-41 142.4 0.0 7.8e-25 87.4 0.0 2.3 2 0 0 2 2 2 2 Trehalose-phosphatase Glycos_transf_1 PF00534.20 ORY37380.1 - 0.0042 16.6 0.9 2 7.9 0.2 2.9 2 1 0 2 2 2 2 Glycosyl transferases group 1 SPX PF03105.19 ORY37380.1 - 0.41 10.5 5.0 0.63 9.9 5.0 1.2 1 0 0 1 1 1 0 SPX domain p450 PF00067.22 ORY37381.1 - 7.7e-77 259.0 0.0 5.4e-57 193.6 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 AMP-binding PF00501.28 ORY37382.1 - 4.3e-35 121.1 0.1 6.1e-35 120.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MAGE_N PF12440.8 ORY37382.1 - 7.1 7.4 9.9 16 6.2 9.9 1.6 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal Ank_2 PF12796.7 ORY37383.1 - 3.7e-25 88.3 0.0 3e-12 46.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY37383.1 - 1.6e-22 79.3 2.0 5e-07 29.9 0.0 4.8 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY37383.1 - 5.9e-22 75.4 1.1 0.00048 20.4 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 ORY37383.1 - 3e-17 62.2 3.5 0.0014 19.0 0.4 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 ORY37383.1 - 8.8e-17 61.2 0.1 1.7e-08 34.8 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeats (many copies) PP-binding PF00550.25 ORY37383.1 - 0.0016 18.8 0.0 0.0057 17.0 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site Spt5_N PF11942.8 ORY37383.1 - 8.9 7.4 7.6 65 4.6 0.0 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CM2 PF03021.14 ORY37384.1 - 0.12 12.2 1.8 0.21 11.4 1.8 1.5 1 0 0 1 1 1 0 Influenza C virus M2 protein Stevor PF17410.2 ORY37384.1 - 9.6 5.7 7.3 13 5.2 7.3 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame M20_dimer PF07687.14 ORY37385.1 - 1.1e-09 38.2 0.0 2e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 Peptidase dimerisation domain KIX PF02172.16 ORY37385.1 - 0.15 12.4 0.7 0.28 11.5 0.7 1.4 1 0 0 1 1 1 0 KIX domain Na_Ca_ex PF01699.24 ORY37386.1 - 1.5e-19 70.4 23.8 3.2e-12 46.6 3.2 3.3 2 2 0 2 2 2 2 Sodium/calcium exchanger protein YccF PF03733.13 ORY37386.1 - 0.00019 22.1 29.1 0.0022 18.7 0.3 5.2 5 0 0 5 5 5 2 Inner membrane component domain RNA_pol_3_Rpc31 PF11705.8 ORY37386.1 - 0.069 13.4 5.2 0.19 12.0 5.2 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SURF2 PF05477.11 ORY37386.1 - 0.2 11.3 4.9 0.48 10.1 4.9 1.6 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) NOA36 PF06524.12 ORY37386.1 - 1.4 8.1 12.2 3.4 6.9 12.2 1.6 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 ORY37386.1 - 2.1 6.5 7.1 3.8 5.7 7.1 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 ORY37386.1 - 5.1 5.2 8.1 11 4.1 8.1 1.4 1 0 0 1 1 1 0 Nop14-like family zf-C3HC4 PF00097.25 ORY37387.1 - 2.8e-10 39.9 5.0 5.5e-10 38.9 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY37387.1 - 2.3e-08 33.7 4.8 1.1e-07 31.6 5.1 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY37387.1 - 4.8e-08 33.2 5.7 1.1e-07 32.1 5.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORY37387.1 - 4.3e-07 29.7 4.6 7.8e-07 28.9 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY37387.1 - 5.2e-07 29.6 4.6 5.2e-07 29.6 4.6 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY37387.1 - 8.3e-07 28.9 5.0 1.6e-06 27.9 5.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORY37387.1 - 0.00028 21.0 7.1 0.00028 21.0 7.1 2.7 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ORY37387.1 - 0.0021 17.9 4.5 0.0053 16.6 4.5 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 ORY37387.1 - 0.0029 17.9 3.4 0.0075 16.5 3.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain TerY_C PF15616.6 ORY37387.1 - 0.33 11.1 2.7 0.77 9.9 2.7 1.6 1 0 0 1 1 1 0 TerY-C metal binding domain zf-ANAPC11 PF12861.7 ORY37387.1 - 0.37 10.9 2.8 0.75 9.9 2.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 ORY37387.1 - 1.8 8.4 5.1 3.6 7.4 3.2 2.4 2 0 0 2 2 2 0 RING-like zinc finger DUF1619 PF07773.11 ORY37388.1 - 4.7e-41 141.7 10.0 4.7e-41 141.7 10.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1619) TGS PF02824.21 ORY37388.1 - 0.15 12.1 0.2 1.5 8.9 0.0 2.6 3 0 0 3 3 3 0 TGS domain EAP30 PF04157.16 ORY37389.1 - 1.3e-75 253.7 0.3 1.4e-75 253.6 0.3 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family PilJ PF13675.6 ORY37389.1 - 0.049 13.7 0.5 0.099 12.7 0.5 1.5 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF5098 PF17023.5 ORY37389.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5098) QLQ PF08880.11 ORY37389.1 - 0.75 9.6 6.6 2.1 8.2 6.6 1.7 1 0 0 1 1 1 0 QLQ PDEase_I PF00233.19 ORY37391.1 - 1.8e-70 237.4 0.0 2e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Transport_MerF PF11431.8 ORY37391.1 - 0.012 15.4 0.3 0.072 13.0 0.0 2.1 2 0 0 2 2 2 0 Membrane transport protein MerF HVSL PF09749.9 ORY37392.1 - 9.8e-39 133.2 0.1 1.5e-38 132.7 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 ORY37392.1 - 0.046 13.6 0.0 0.28 11.1 0.0 2.0 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily PCNA_N PF00705.18 ORY37392.1 - 0.12 12.1 0.2 0.97 9.2 0.0 2.1 2 0 0 2 2 2 0 Proliferating cell nuclear antigen, N-terminal domain RTT107_BRCT_5 PF16770.5 ORY37393.1 - 2.6e-11 43.3 0.1 5.3e-11 42.3 0.1 1.5 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 ORY37393.1 - 3.7e-08 33.6 0.2 0.00017 21.9 0.1 2.9 2 1 1 3 3 3 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 ORY37393.1 - 4.8e-06 26.9 0.0 0.011 16.1 0.0 2.2 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain GATA PF00320.27 ORY37396.1 - 1e-09 37.8 8.8 2.1e-09 36.8 8.8 1.5 1 0 0 1 1 1 1 GATA zinc finger Med19 PF10278.9 ORY37397.1 - 0.018 15.0 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 SDA1 PF05285.12 ORY37398.1 - 3.4e-77 260.2 49.5 3.4e-77 260.2 49.5 2.2 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 ORY37398.1 - 6.2e-19 68.1 0.1 2.6e-18 66.1 0.1 2.2 2 0 0 2 2 2 1 NUC130/3NT domain Cnd1 PF12717.7 ORY37398.1 - 0.023 14.7 1.4 0.075 13.1 1.4 1.9 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 zf-RING_2 PF13639.6 ORY37399.1 - 1.1e-09 38.4 4.4 1.1e-09 38.4 4.4 4.7 3 2 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY37399.1 - 1.5e-09 37.5 3.7 1.5e-09 37.5 3.7 4.5 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY37399.1 - 2.1e-08 33.9 3.6 2.1e-08 33.9 3.6 3.6 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY37399.1 - 8.8e-08 32.1 7.0 8.8e-08 32.1 7.0 3.7 4 1 0 4 4 4 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORY37399.1 - 3.2e-07 30.1 0.6 3.2e-07 30.1 0.6 3.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 ORY37399.1 - 1.3e-05 24.9 3.5 1.3e-05 24.9 3.5 2.4 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 ORY37399.1 - 2.3e-05 24.6 4.1 2.3e-05 24.6 4.1 4.0 3 3 0 3 3 3 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 ORY37399.1 - 4.4e-05 23.6 5.9 4.4e-05 23.6 5.9 3.2 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 ORY37399.1 - 4.6e-05 23.3 2.5 4.6e-05 23.3 2.5 3.4 3 1 0 3 3 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY37399.1 - 0.00017 21.4 3.7 0.00017 21.4 3.7 3.0 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 ORY37399.1 - 0.01 15.6 0.2 0.01 15.6 0.2 3.3 4 1 0 4 4 4 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 ORY37399.1 - 1.3 8.8 15.8 2.1 8.2 4.2 3.0 2 0 0 2 2 2 0 RING-like zinc finger DM PF00751.18 ORY37399.1 - 3.4 7.6 16.3 8.1 6.4 4.8 3.1 1 1 1 2 2 2 0 DM DNA binding domain Glyco_hydro_26 PF02156.15 ORY37400.1 - 7.6e-09 35.4 6.4 2.2e-05 24.1 0.3 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 EF-hand_5 PF13202.6 ORY37400.1 - 0.08 12.5 0.1 0.25 10.9 0.1 1.9 1 0 0 1 1 1 0 EF hand PalH PF08733.10 ORY37401.1 - 0.16 11.0 7.3 0.045 12.7 3.8 1.8 2 1 0 2 2 2 0 PalH/RIM21 RRM_1 PF00076.22 ORY37402.1 - 2.7e-57 190.5 13.9 7.4e-15 54.5 0.4 6.4 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY37402.1 - 1.7e-05 24.4 0.1 0.0017 17.9 0.0 3.6 3 1 1 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY37402.1 - 5.7e-05 23.2 0.1 2.1 8.5 0.0 4.3 4 0 0 4 4 4 2 RNA recognition motif RRM_occluded PF16842.5 ORY37402.1 - 0.0026 17.6 1.5 0.16 11.8 0.0 4.0 5 0 0 5 5 5 1 Occluded RNA-recognition motif DUF3726 PF12525.8 ORY37402.1 - 0.095 12.8 0.0 2.1 8.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3726) TPR_1 PF00515.28 ORY37403.1 - 5.2e-17 60.9 0.4 5.1e-05 22.9 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY37403.1 - 4.1e-14 51.5 0.2 0.002 18.1 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 ORY37403.1 - 8e-10 38.7 0.1 0.064 13.9 0.0 4.7 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY37403.1 - 5.8e-09 35.5 0.0 0.0037 17.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY37403.1 - 7.9e-07 29.6 0.0 0.0066 17.1 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY37403.1 - 4.2e-05 24.0 0.0 0.00013 22.5 0.0 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY37403.1 - 5.7e-05 23.2 0.4 0.45 11.0 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY37403.1 - 0.00018 21.8 0.1 4.1 7.8 0.1 3.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY37403.1 - 0.00023 20.8 0.0 0.0042 16.7 0.0 3.0 2 2 2 4 4 4 1 TPR repeat TPR_7 PF13176.6 ORY37403.1 - 0.00082 19.2 0.1 11 6.3 0.0 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 ORY37403.1 - 0.013 15.2 0.0 0.031 14.0 0.0 1.6 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain TPR_9 PF13371.6 ORY37403.1 - 0.02 15.0 0.0 3.3 7.9 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat SusD-like_3 PF14322.6 ORY37403.1 - 0.023 15.0 1.0 0.14 12.5 0.2 2.1 1 1 1 2 2 2 0 Starch-binding associating with outer membrane Y_phosphatase2 PF03162.13 ORY37408.1 - 1.3e-20 73.6 0.0 1.4e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 ORY37408.1 - 0.0033 17.2 0.0 0.0039 17.0 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 ORY37408.1 - 0.031 14.3 0.1 0.052 13.5 0.1 1.5 1 1 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 ORY37408.1 - 0.033 13.8 0.0 0.072 12.6 0.0 1.5 1 1 1 2 2 2 0 Protein-tyrosine phosphatase Peptidase_M1 PF01433.20 ORY37409.1 - 1.5e-38 132.6 5.3 2.3e-38 131.9 5.3 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 ORY37409.1 - 2.4e-12 47.4 0.0 8.5e-12 45.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain HEAT_2 PF13646.6 ORY37409.1 - 7e-06 26.4 13.3 0.019 15.3 1.8 4.7 1 1 3 4 4 4 3 HEAT repeats A_deaminase PF00962.22 ORY37411.1 - 1.5e-125 418.9 0.2 2e-125 418.5 0.2 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Clathrin PF00637.20 ORY37412.1 - 3.2e-207 678.7 35.4 2.6e-34 118.1 0.3 7.8 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 ORY37412.1 - 2e-38 128.8 2.1 3.8e-08 33.2 0.0 6.5 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 ORY37412.1 - 2.8e-31 107.2 0.1 2.2e-30 104.4 0.1 2.6 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.10 ORY37412.1 - 3e-10 39.3 1.0 9e-10 37.7 1.0 1.9 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.14 ORY37412.1 - 3.6e-08 32.9 5.2 0.0016 17.6 0.0 4.4 4 1 0 4 4 4 2 Coatomer WD associated region TPR_14 PF13428.6 ORY37412.1 - 7.1e-05 23.3 6.8 2.4 9.2 0.0 7.8 9 1 1 10 10 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY37412.1 - 0.00079 19.1 0.2 2.7 8.0 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY37412.1 - 0.0017 18.4 0.0 0.64 10.4 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY37412.1 - 0.0062 16.6 5.3 5.9 7.3 0.0 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY37412.1 - 0.0062 16.5 5.8 17 5.7 0.3 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY37412.1 - 0.046 14.2 2.1 12 6.5 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3447 PF11929.8 ORY37412.1 - 0.73 9.8 2.7 0.73 9.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3447) TPR_12 PF13424.6 ORY37412.1 - 1.4 9.3 7.4 15 5.9 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat ATP-synt_C PF00137.21 ORY37413.1 - 3.2e-33 113.9 35.2 3.6e-20 72.1 12.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TPR_19 PF14559.6 ORY37414.1 - 2.7e-48 162.4 23.0 0.00011 22.6 0.1 16.9 15 3 4 19 19 18 9 Tetratricopeptide repeat TPR_2 PF07719.17 ORY37414.1 - 5.1e-37 123.0 35.3 0.016 15.3 0.0 20.6 21 0 0 21 21 20 7 Tetratricopeptide repeat TPR_14 PF13428.6 ORY37414.1 - 2.2e-33 112.1 2.7 0.0012 19.5 0.1 16.7 16 3 3 19 19 16 4 Tetratricopeptide repeat TPR_16 PF13432.6 ORY37414.1 - 7e-30 103.4 0.0 1.5e-05 25.5 0.0 12.6 11 2 2 13 13 13 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORY37414.1 - 3.5e-25 86.7 45.8 0.026 14.3 0.2 17.4 19 0 0 19 19 18 7 Tetratricopeptide repeat TPR_8 PF13181.6 ORY37414.1 - 3.8e-25 86.0 32.4 0.0012 18.9 0.0 14.5 15 0 0 15 15 15 7 Tetratricopeptide repeat TPR_12 PF13424.6 ORY37414.1 - 3.6e-24 84.8 25.3 0.0017 18.6 0.2 14.1 10 5 3 13 13 12 6 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY37414.1 - 7.2e-18 64.6 40.8 8e-05 22.8 0.1 12.9 10 2 2 13 13 13 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 ORY37414.1 - 1.6e-16 59.0 16.3 0.045 13.8 0.0 12.2 14 1 1 15 15 12 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORY37414.1 - 1.6e-11 43.6 17.6 1.3 8.8 0.1 13.6 15 3 2 17 17 16 2 TPR repeat TPR_6 PF13174.6 ORY37414.1 - 2.2e-10 40.5 35.4 0.12 13.1 0.4 15.9 19 0 0 19 19 15 2 Tetratricopeptide repeat TPR_4 PF07721.14 ORY37414.1 - 5.6e-10 38.9 0.2 0.24 12.1 0.5 8.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY37414.1 - 9.6e-10 38.2 23.1 0.12 12.8 0.1 13.5 17 0 0 17 17 12 2 Tetratricopeptide repeat TPR_21 PF09976.9 ORY37414.1 - 9.8e-07 28.7 20.3 0.72 9.5 0.6 7.1 6 2 1 7 7 7 3 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 ORY37414.1 - 1.8e-06 27.6 24.4 0.031 13.7 0.3 7.8 6 2 3 9 9 9 3 MalT-like TPR region TPR_9 PF13371.6 ORY37414.1 - 1.2e-05 25.3 4.9 3.2 8.0 0.0 8.5 9 1 1 10 10 9 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORY37414.1 - 6.5e-05 22.7 18.0 0.041 13.8 0.1 9.3 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_20 PF14561.6 ORY37414.1 - 0.00039 20.7 15.4 2.5 8.5 0.1 9.4 9 2 3 12 12 11 1 Tetratricopeptide repeat SNAP PF14938.6 ORY37414.1 - 0.0026 17.2 30.1 0.26 10.7 0.1 8.3 8 2 1 9 9 9 2 Soluble NSF attachment protein, SNAP SPOB_a PF14689.6 ORY37414.1 - 0.0054 16.4 0.5 0.89 9.3 0.0 4.7 5 0 0 5 5 5 1 Sensor_kinase_SpoOB-type, alpha-helical domain Fis1_TPR_C PF14853.6 ORY37414.1 - 0.015 15.4 9.4 30 4.8 0.0 7.6 8 0 0 8 8 8 0 Fis1 C-terminal tetratricopeptide repeat PMEI PF04043.15 ORY37414.1 - 0.042 14.2 1.9 0.094 13.1 0.2 2.6 2 0 0 2 2 1 0 Plant invertase/pectin methylesterase inhibitor UNC45-central PF11701.8 ORY37414.1 - 0.046 13.7 0.2 4.2 7.3 0.0 3.5 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central Clathrin PF00637.20 ORY37414.1 - 0.11 12.4 6.1 3.5 7.5 0.0 5.0 5 1 0 5 5 5 0 Region in Clathrin and VPS PRA1 PF03208.19 ORY37415.1 - 9.1e-25 87.0 2.2 1.1e-24 86.7 2.2 1.0 1 0 0 1 1 1 1 PRA1 family protein P21-Arc PF04062.14 ORY37416.1 - 1.7e-48 164.9 0.0 2.1e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Ribosomal_L5_C PF00673.21 ORY37417.1 - 2.6e-22 78.8 0.0 3.9e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 ORY37417.1 - 4.8e-20 71.6 0.0 3.3e-19 69.0 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L5 Ribosomal_S8 PF00410.19 ORY37418.1 - 2.9e-18 66.1 0.0 1.8e-17 63.5 0.0 1.8 1 1 0 1 1 1 1 Ribosomal protein S8 LSM PF01423.22 ORY37419.1 - 1.4e-19 69.5 0.5 1.7e-19 69.2 0.5 1.1 1 0 0 1 1 1 1 LSM domain DNA_ligase_A_M PF01068.21 ORY37420.1 - 6.5e-51 172.9 0.0 1.1e-50 172.1 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 ORY37420.1 - 1.9e-34 119.5 0.1 6.3e-34 117.8 0.2 1.9 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 ORY37420.1 - 9.6e-14 51.8 0.0 2.6e-13 50.4 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RCC1 PF00415.18 ORY37420.1 - 1.4e-11 44.8 5.1 2.3e-07 31.3 0.0 4.9 4 1 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY37420.1 - 2.6e-10 39.8 11.3 6.8e-05 22.6 2.6 4.0 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RNA_ligase PF09414.10 ORY37420.1 - 1.2e-08 35.4 0.1 3.4e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 RNA ligase BRCT_2 PF16589.5 ORY37420.1 - 3.5e-06 27.3 0.1 4.4e-05 23.8 0.0 2.9 4 0 0 4 4 4 1 BRCT domain, a BRCA1 C-terminus domain mRNA_cap_enzyme PF01331.19 ORY37420.1 - 0.00051 19.9 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain DNA_ligase_IV PF11411.8 ORY37420.1 - 0.017 15.2 0.1 0.042 14.0 0.1 1.7 1 0 0 1 1 1 0 DNA ligase IV LIG3_BRCT PF16759.5 ORY37420.1 - 0.042 14.1 0.0 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain Yippee-Mis18 PF03226.14 ORY37421.1 - 1.3e-15 57.5 2.7 1.5e-15 57.3 2.7 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 ORY37421.1 - 0.003 17.8 0.8 0.0038 17.5 0.8 1.1 1 0 0 1 1 1 1 C-terminal domain of RIG-I zf-RING_13 PF17977.1 ORY37421.1 - 0.028 14.6 1.3 0.056 13.6 1.3 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain LIM PF00412.22 ORY37421.1 - 0.4 11.0 4.3 3.8 7.8 0.4 2.4 2 1 0 2 2 2 0 LIM domain tRNA_int_endo PF01974.17 ORY37422.1 - 7.8e-17 61.1 0.0 1.3e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Translin PF01997.16 ORY37422.1 - 0.051 13.6 0.0 0.068 13.1 0.0 1.2 1 0 0 1 1 1 0 Translin family zf-RING_2 PF13639.6 ORY37423.1 - 2.7e-14 53.2 8.6 5.2e-13 49.1 4.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 ORY37423.1 - 7.8e-09 35.7 3.3 2.3e-08 34.2 3.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORY37423.1 - 1.6e-08 34.3 4.1 1.6e-08 34.3 4.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY37423.1 - 1.1e-07 31.5 3.2 2.8e-07 30.2 3.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 ORY37423.1 - 7.6e-07 28.9 3.1 7.6e-07 28.9 3.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY37423.1 - 1.5e-05 24.7 5.7 3e-05 23.8 1.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY37423.1 - 7.1e-05 22.7 2.8 7.1e-05 22.7 2.8 1.6 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY37423.1 - 0.00019 21.4 5.6 0.00068 19.6 2.9 2.5 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 ORY37423.1 - 0.0045 16.8 3.9 0.0045 16.8 3.9 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 ORY37423.1 - 0.019 14.8 2.3 0.036 13.9 2.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 ORY37423.1 - 0.02 14.9 3.4 0.079 13.0 3.4 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 ORY37423.1 - 0.056 13.1 3.6 0.13 11.9 3.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 ORY37423.1 - 0.16 11.9 3.6 0.29 11.0 3.6 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 ORY37423.1 - 0.31 11.2 4.8 1.3 9.2 4.8 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 ORY37423.1 - 0.38 10.9 4.4 0.72 10.0 4.4 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_10 PF16685.5 ORY37423.1 - 0.58 10.3 2.3 1.1 9.4 2.3 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 ORY37423.1 - 1.4 9.1 9.3 13 6.0 4.7 2.8 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 ORY37423.1 - 1.5 9.2 3.7 2.7 8.4 3.7 1.4 1 0 0 1 1 1 0 RING-like domain Mit_KHE1 PF10173.9 ORY37424.1 - 0.21 11.7 2.8 5.2 7.1 2.8 2.6 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF3439 PF11921.8 ORY37424.1 - 0.22 11.5 9.7 0.89 9.5 9.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FSA_C PF10479.9 ORY37424.1 - 5.6 5.0 10.1 12 3.8 10.1 1.5 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus RPN2_C PF18004.1 ORY37425.1 - 4e-51 173.1 4.7 4e-51 173.1 4.7 2.2 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 ORY37425.1 - 1e-35 120.4 22.8 4.3e-09 36.3 0.1 8.3 8 0 0 8 8 8 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 ORY37425.1 - 4.3e-19 68.7 5.1 2e-13 50.6 0.3 4.3 4 1 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 ORY37425.1 - 6.6e-06 26.5 0.5 0.023 15.2 0.1 4.4 4 0 0 4 4 4 1 HEAT-like repeat HEAT PF02985.22 ORY37425.1 - 0.00018 21.4 1.2 8.6 6.9 0.1 5.0 4 0 0 4 4 4 1 HEAT repeat Adaptin_N PF01602.20 ORY37425.1 - 0.064 11.8 0.1 13 4.2 0.0 2.7 2 1 0 2 2 2 0 Adaptin N terminal region DUF2052 PF09747.9 ORY37425.1 - 0.13 12.4 10.4 0.69 10.0 4.2 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) RNA_pol_Rpc4 PF05132.14 ORY37425.1 - 0.14 12.6 10.0 0.067 13.6 0.5 2.4 2 0 0 2 2 2 0 RNA polymerase III RPC4 DUF913 PF06025.12 ORY37425.1 - 2.1 7.3 9.4 6.5 5.6 0.6 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Sigma70_ner PF04546.13 ORY37425.1 - 4.9 7.0 12.3 0.068 13.0 2.6 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region TPR_16 PF13432.6 ORY37426.1 - 0.031 14.9 0.1 0.062 14.0 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Ninjurin PF04923.12 ORY37426.1 - 0.13 12.2 0.2 0.32 11.0 0.1 1.6 2 0 0 2 2 2 0 Ninjurin CsgE PF10627.9 ORY37427.1 - 0.12 12.7 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Curli assembly protein CsgE V-ATPase_H_N PF03224.14 ORY37428.1 - 0.01 15.1 2.6 0.089 12.1 1.2 2.8 2 1 0 2 2 2 0 V-ATPase subunit H Sas10 PF09368.10 ORY37429.1 - 1e-23 83.6 5.4 5.1e-23 81.3 5.4 2.3 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 ORY37429.1 - 1.4e-07 32.0 0.1 1.4e-07 32.0 0.1 2.7 2 1 0 2 2 2 1 Sas10/Utp3/C1D family ATP19 PF11022.8 ORY37429.1 - 0.75 10.2 2.4 4.9 7.6 2.4 2.5 1 0 0 1 1 1 0 ATP synthase subunit K TMIE PF16038.5 ORY37429.1 - 3.4 7.6 4.7 19 5.2 0.1 3.0 2 0 0 2 2 2 0 TMIE protein DHHC PF01529.20 ORY37430.1 - 0.1 12.7 4.5 0.13 12.4 4.2 1.4 1 1 0 1 1 1 0 DHHC palmitoyltransferase TAP_C PF03943.13 ORY37431.1 - 1.8e-12 46.7 0.4 1.8e-12 46.7 0.4 2.1 3 0 0 3 3 3 1 TAP C-terminal domain NTF2 PF02136.20 ORY37431.1 - 3.6e-08 34.0 0.0 1e-07 32.5 0.0 1.8 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_9 PF18444.1 ORY37431.1 - 5.5e-07 29.3 0.1 1.2e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif DUF604 PF04646.12 ORY37432.1 - 4.5e-08 32.8 0.4 7.2e-08 32.1 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 ORY37432.1 - 1.9e-07 30.8 0.1 3.1e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.21 ORY37432.1 - 0.013 15.3 0.1 0.063 13.1 0.0 1.9 2 0 0 2 2 2 0 Galactosyltransferase Choline_kinase PF01633.20 ORY37433.1 - 6e-54 182.9 0.0 1.7e-53 181.4 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 ORY37433.1 - 1.8e-10 41.2 0.0 2.8e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ORY37433.1 - 0.00042 19.7 0.2 0.0025 17.2 0.2 2.1 1 1 0 1 1 1 1 Ecdysteroid kinase DNA_photolyase PF00875.18 ORY37433.1 - 0.021 14.8 0.0 0.049 13.6 0.0 1.6 1 1 0 1 1 1 0 DNA photolyase DUF1679 PF07914.11 ORY37433.1 - 0.022 13.6 0.0 0.048 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) WH2 PF02205.20 ORY37434.1 - 0.0068 16.2 0.2 0.012 15.4 0.2 1.4 1 0 0 1 1 1 1 WH2 motif PBD PF00786.28 ORY37435.1 - 1.9e-14 53.7 0.6 4.3e-14 52.6 0.1 1.9 2 0 0 2 2 2 1 P21-Rho-binding domain WH1 PF00568.23 ORY37435.1 - 4.6e-11 42.6 0.1 7e-11 42.0 0.1 1.2 1 0 0 1 1 1 1 WH1 domain Tyrosinase PF00264.20 ORY37436.1 - 3.6e-41 141.9 2.2 1.1e-40 140.3 2.2 1.7 1 1 0 1 1 1 1 Common central domain of tyrosinase Peptidase_M28 PF04389.17 ORY37437.1 - 1.6e-37 129.1 0.0 3e-37 128.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 ORY37437.1 - 2.1e-08 34.1 0.1 8.3e-08 32.2 0.1 2.0 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 ORY37437.1 - 0.0016 18.2 0.0 0.0036 17.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF3131 PF11329.8 ORY37437.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3131) MFS18 PF17352.2 ORY37437.1 - 1.2 9.6 6.5 0.45 10.9 1.1 2.6 1 1 1 2 2 2 0 Male Flower Specific protein 18 DnaJ PF00226.31 ORY37439.1 - 2.4e-18 66.0 0.6 7e-18 64.5 0.6 1.9 1 0 0 1 1 1 1 DnaJ domain BT1 PF03092.16 ORY37439.1 - 0.28 9.4 1.8 0.41 8.8 1.8 1.2 1 0 0 1 1 1 0 BT1 family MscS_TM PF12794.7 ORY37439.1 - 7 5.4 5.6 13 4.6 5.6 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Thioredoxin_8 PF13905.6 ORY37440.1 - 1.2e-19 70.4 0.0 7.9e-18 64.6 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin-like ZZ PF00569.17 ORY37440.1 - 6e-10 38.8 5.7 1.5e-09 37.5 5.7 1.7 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 ORY37440.1 - 0.00083 19.6 5.5 0.0026 18.1 5.5 1.9 1 0 0 1 1 1 1 C1 domain dCache_1 PF02743.18 ORY37440.1 - 0.12 12.1 0.1 1.2 8.8 0.0 2.4 2 1 0 2 2 2 0 Cache domain Zn_Tnp_IS91 PF14319.6 ORY37440.1 - 0.18 11.8 4.0 0.53 10.3 4.0 1.7 1 0 0 1 1 1 0 Transposase zinc-binding domain DUF4718 PF15842.5 ORY37441.1 - 0.0073 16.1 0.2 0.0079 16.0 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4718) ANAPC4_WD40 PF12894.7 ORY37443.1 - 9e-06 25.9 0.0 0.0096 16.2 0.0 3.7 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY37443.1 - 0.0074 17.1 0.3 17 6.5 0.0 4.3 2 1 0 2 2 2 1 WD domain, G-beta repeat DUF4452 PF14618.6 ORY37443.1 - 0.43 10.4 7.7 0.47 10.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4452) MRP-S26 PF14943.6 ORY37444.1 - 0.02 14.8 0.4 0.14 12.1 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 MMU163 PF17119.5 ORY37444.1 - 0.27 10.4 2.7 0.12 11.5 0.5 1.5 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis Cation_ATPase_C PF00689.21 ORY37445.1 - 2.6e-38 131.5 8.8 2.6e-38 131.5 8.8 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 ORY37445.1 - 3.9e-38 130.8 2.2 3.9e-38 130.8 2.2 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 ORY37445.1 - 1.5e-17 63.4 0.0 3.8e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY37445.1 - 1.1e-15 58.5 0.1 9.9e-13 48.9 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORY37445.1 - 0.0027 17.5 0.3 0.0076 16.0 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY37445.1 - 0.02 14.6 2.8 0.19 11.5 0.0 3.4 3 0 0 3 3 3 0 Cation transporter/ATPase, N-terminus OppC_N PF12911.7 ORY37445.1 - 0.032 14.2 7.9 0.054 13.5 5.3 2.8 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Cation_ATPase_C PF00689.21 ORY37446.1 - 1.5e-40 138.8 4.8 1.5e-40 138.8 4.8 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 ORY37446.1 - 2.3e-38 131.5 3.3 2.3e-38 131.5 3.3 2.9 3 1 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 ORY37446.1 - 4.2e-18 65.2 0.0 9.7e-18 64.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY37446.1 - 2.4e-15 57.4 1.0 3.1e-14 53.7 1.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY37446.1 - 5.8e-07 29.1 0.5 8.5e-06 25.4 0.0 2.9 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY37446.1 - 0.0035 17.1 0.4 0.0079 16.0 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase OppC_N PF12911.7 ORY37446.1 - 0.22 11.5 7.8 0.062 13.3 3.3 2.4 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C KH_1 PF00013.29 ORY37447.1 - 4.5e-05 23.2 1.3 6.5e-05 22.7 1.3 1.2 1 0 0 1 1 1 1 KH domain KH_8 PF17903.1 ORY37448.1 - 1.9e-05 24.7 0.0 2.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Krr1 KH1 domain TMEM154 PF15102.6 ORY37449.1 - 0.0054 16.6 12.2 0.008 16.1 0.2 2.7 2 0 0 2 2 2 1 TMEM154 protein family Amnionless PF14828.6 ORY37449.1 - 0.049 12.5 0.0 0.049 12.5 0.0 2.1 2 0 0 2 2 2 0 Amnionless DUF3377 PF11857.8 ORY37449.1 - 0.13 12.2 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) SKG6 PF08693.10 ORY37449.1 - 0.15 11.5 0.2 0.48 9.9 0.2 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Plasmodium_Vir PF05795.11 ORY37449.1 - 3.9 6.8 9.9 1.3 8.4 0.2 2.3 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Abhydrolase_6 PF12697.7 ORY37450.1 - 5.2e-08 33.8 2.9 5.4e-07 30.5 3.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 ORY37450.1 - 1.2e-05 24.9 0.2 2.1e-05 24.1 0.2 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF900 PF05990.12 ORY37450.1 - 1.7e-05 24.4 0.1 4.9e-05 23.0 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Thioesterase PF00975.20 ORY37450.1 - 4.4e-05 23.7 0.0 6.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 ORY37450.1 - 0.00026 20.8 0.6 0.0018 18.0 0.6 2.1 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 ORY37450.1 - 0.0012 18.6 0.2 0.0035 17.0 0.2 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY37450.1 - 0.0026 17.0 0.5 0.019 14.3 0.5 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF915 PF06028.11 ORY37450.1 - 0.012 15.0 0.1 0.89 8.8 0.0 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 ORY37450.1 - 0.026 13.7 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase HlyIII PF03006.20 ORY37451.1 - 2e-42 145.5 23.4 2.3e-42 145.2 23.4 1.0 1 0 0 1 1 1 1 Haemolysin-III related Pkinase PF00069.25 ORY37452.1 - 2.9e-11 43.2 0.0 4.3e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 ORY37452.1 - 0.00011 22.2 0.1 0.00024 21.1 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY37452.1 - 0.00054 19.6 0.0 0.00086 18.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Methyltransf_22 PF13383.6 ORY37453.1 - 1.3e-15 57.7 3.6 3.3e-09 36.7 0.6 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_21 PF05050.12 ORY37453.1 - 1.8e-06 28.1 0.0 4.3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_22 PF13383.6 ORY37454.1 - 4.8e-17 62.4 0.5 7.6e-17 61.7 0.5 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 ORY37454.1 - 6.4e-05 23.0 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Cation_efflux PF01545.21 ORY37455.1 - 0.00034 20.4 0.0 0.00042 20.1 0.0 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORY37455.1 - 0.012 15.7 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter CsgE PF10627.9 ORY37456.1 - 0.12 12.7 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Curli assembly protein CsgE EF-hand_4 PF12763.7 ORY37457.1 - 7.8e-26 90.1 0.0 1.2e-15 57.3 0.0 2.6 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 ORY37457.1 - 5.7e-06 25.5 0.0 0.06 12.9 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 ORY37457.1 - 8.2e-05 22.2 0.0 0.27 11.3 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 ORY37457.1 - 0.00093 19.6 0.0 0.0058 17.1 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 ORY37457.1 - 0.033 14.0 0.0 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair SH3_9 PF14604.6 ORY37459.1 - 1.2e-22 79.5 0.4 9.4e-11 41.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 ORY37459.1 - 9.5e-20 70.0 0.9 9.5e-11 41.1 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 ORY37459.1 - 2.3e-14 52.8 0.0 1.3e-06 28.0 0.0 2.2 2 0 0 2 2 2 2 Variant SH3 domain SH3_10 PF17902.1 ORY37459.1 - 0.00057 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 ORY37459.1 - 0.17 12.2 0.3 0.61 10.4 0.1 1.9 2 0 0 2 2 2 0 Bacterial SH3 domain RhoGEF PF00621.20 ORY37460.1 - 2.4e-37 128.9 0.4 3e-37 128.6 0.4 1.1 1 0 0 1 1 1 1 RhoGEF domain PH_13 PF16652.5 ORY37460.1 - 2.7e-13 50.0 0.0 5.3e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PID_2 PF14719.6 ORY37460.1 - 0.025 14.5 0.5 0.038 13.9 0.5 1.3 1 0 0 1 1 1 0 Phosphotyrosine interaction domain (PTB/PID) GDA1_CD39 PF01150.17 ORY37461.1 - 1.6e-93 313.7 0.0 2.2e-93 313.3 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 ORY37461.1 - 0.049 13.1 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Ppx/GppA phosphatase family RNA_pol_Rpb1_4 PF05000.17 ORY37461.1 - 0.12 12.4 0.2 0.28 11.1 0.2 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 Dsh_C PF12316.8 ORY37461.1 - 1 9.8 7.1 0.11 12.9 2.0 1.8 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal RXT2_N PF08595.11 ORY37462.1 - 0.061 13.3 5.6 0.1 12.6 5.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal PAT1 PF09770.9 ORY37462.1 - 5.8 5.1 11.4 8.9 4.4 11.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Apt1 PF10351.9 ORY37463.1 - 5.1e-106 355.4 23.9 4.3e-73 246.8 8.7 3.3 2 1 1 3 3 3 2 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 ORY37463.1 - 4e-36 124.9 14.3 4e-36 124.9 14.3 2.5 2 1 1 3 3 3 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.9 ORY37463.1 - 7.1e-31 107.4 0.4 3.2e-30 105.3 0.0 2.3 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 ORY37463.1 - 2.6e-19 69.7 0.1 8.3e-19 68.0 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) DUF2604 PF10790.9 ORY37463.1 - 0.14 12.4 0.1 0.38 11.1 0.1 1.7 1 0 0 1 1 1 0 Protein of Unknown function (DUF2604) Fmp27_SW PF10305.9 ORY37463.1 - 0.35 11.6 10.6 5.4 7.8 0.0 4.3 3 1 1 4 4 4 0 RNA pol II promoter Fmp27 protein domain NicO PF03824.16 ORY37463.1 - 6 6.1 7.0 14 4.9 7.0 1.5 1 0 0 1 1 1 0 High-affinity nickel-transport protein Pro_isomerase PF00160.21 ORY37464.1 - 2.4e-47 161.1 0.2 2.7e-47 161.0 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD eIF-3_zeta PF05091.12 ORY37465.1 - 1.2e-152 509.6 0.0 1.3e-152 509.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) GTP_EFTU PF00009.27 ORY37466.1 - 3.2e-20 72.5 0.0 7.6e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 ORY37466.1 - 4.9e-08 33.3 0.5 2e-07 31.3 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 ORY37466.1 - 0.001 19.4 0.3 0.0041 17.4 0.2 2.2 2 1 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 ORY37466.1 - 0.0061 16.6 0.2 0.02 14.9 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 ORY37466.1 - 0.01 15.6 0.7 7.3 6.3 0.0 3.8 3 1 1 4 4 4 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 ORY37466.1 - 0.016 15.1 1.1 3.6 7.4 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase Roc PF08477.13 ORY37466.1 - 0.13 12.5 0.0 6.4 7.0 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ThiF PF00899.21 ORY37467.1 - 2.3e-33 115.6 0.1 3.1e-33 115.2 0.1 1.1 1 0 0 1 1 1 1 ThiF family E1_4HB PF16191.5 ORY37467.1 - 0.00064 19.9 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle UreE_N PF02814.15 ORY37467.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain SET PF00856.28 ORY37468.1 - 2.2e-11 44.4 0.0 4e-11 43.6 0.0 1.6 1 1 0 1 1 1 1 SET domain IML1 PF12257.8 ORY37470.1 - 5e-111 370.4 0.0 2.9e-110 367.9 0.0 2.0 2 0 0 2 2 2 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 ORY37470.1 - 2.8e-21 75.3 1.2 5.1e-21 74.5 0.3 2.0 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CsgE PF10627.9 ORY37472.1 - 0.079 13.2 0.1 0.079 13.2 0.1 1.1 1 0 0 1 1 1 0 Curli assembly protein CsgE Plasmid_RAQPRD PF09686.10 ORY37473.1 - 0.35 11.1 3.0 0.53 10.5 0.6 2.7 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) LUC7 PF03194.15 ORY37473.1 - 0.63 9.7 4.0 1 9.0 4.0 1.3 1 0 0 1 1 1 0 LUC7 N_terminus XhlA PF10779.9 ORY37473.1 - 1.3 9.2 4.6 0.41 10.9 0.6 2.2 2 0 0 2 2 2 0 Haemolysin XhlA FAM199X PF15814.5 ORY37473.1 - 4.3 6.3 15.1 1.2 8.2 11.7 1.8 1 1 0 2 2 2 0 Protein family FAM199X PPR_long PF17177.4 ORY37474.1 - 0.097 12.0 0.0 0.94 8.8 0.0 2.3 3 0 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP PEN-2 PF10251.9 ORY37475.1 - 1.8e-26 92.4 2.6 2.3e-26 92.0 2.6 1.1 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase DUF3302 PF11742.8 ORY37475.1 - 0.013 15.6 3.2 0.028 14.5 3.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3302) DUF1772 PF08592.11 ORY37475.1 - 0.028 14.7 0.0 0.034 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) SHE3 PF17078.5 ORY37476.1 - 0.36 10.5 7.3 0.65 9.7 7.3 1.4 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 zf-C2H2_12 PF18658.1 ORY37476.1 - 0.39 10.3 2.6 2 8.0 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger C2H2-type DivIC PF04977.15 ORY37476.1 - 1.2 9.0 9.7 2.6 7.9 9.7 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF2046 PF09755.9 ORY37476.1 - 4.5 6.4 10.8 0.56 9.4 0.3 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DSPc PF00782.20 ORY37477.1 - 1.6e-23 83.0 0.0 1.7e-23 82.9 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY37477.1 - 0.0064 16.1 0.0 0.0069 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 ORY37477.1 - 0.086 11.8 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain CDKN3 PF05706.12 ORY37477.1 - 0.095 12.4 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 ORY37477.1 - 0.11 12.7 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Init_tRNA_PT PF04179.12 ORY37477.1 - 0.11 12.8 0.0 0.13 12.6 0.0 1.1 1 0 0 1 1 1 0 Rit1 DUSP-like domain Homeodomain PF00046.29 ORY37478.1 - 4.6e-16 58.4 0.9 8.1e-16 57.6 0.9 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY37478.1 - 0.0011 18.8 0.7 0.0011 18.8 0.7 1.9 2 0 0 2 2 2 1 Homeobox KN domain DNA_pol_A_exo1 PF01612.20 ORY37480.1 - 1.5e-07 31.3 0.0 2.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease DUF1388 PF07142.12 ORY37481.1 - 0.045 13.7 10.1 0.12 12.4 10.1 1.8 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) MAD PF05557.13 ORY37481.1 - 0.13 10.6 1.3 0.19 10.0 1.3 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein TolA_bind_tri PF16331.5 ORY37481.1 - 0.18 11.9 2.8 0.42 10.7 2.8 1.5 1 0 0 1 1 1 0 TolA binding protein trimerisation Endonuclease_7 PF02945.15 ORY37481.1 - 1.1 9.3 3.6 6.2 6.8 0.4 2.3 2 0 0 2 2 2 0 Recombination endonuclease VII Tmemb_55A PF09788.9 ORY37481.1 - 2.2 7.3 10.7 1.9 7.5 0.2 3.0 3 0 0 3 3 3 0 Transmembrane protein 55A ZF-HD_dimer PF04770.12 ORY37482.1 - 0.009 16.3 1.3 0.017 15.5 0.1 2.0 2 0 0 2 2 2 1 ZF-HD protein dimerisation region CHORD PF04968.12 ORY37482.1 - 0.01 16.5 6.2 0.068 13.9 1.3 2.4 2 0 0 2 2 2 0 CHORD zf-C2H2 PF00096.26 ORY37482.1 - 3.9 8.1 9.6 2.7 8.6 0.4 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type Med11 PF10280.9 ORY37483.1 - 1.6e-10 41.6 1.2 1.6e-10 41.6 1.2 1.6 1 1 1 2 2 2 1 Mediator complex protein CENP-R PF06729.12 ORY37483.1 - 0.014 15.3 4.6 0.85 9.5 1.2 2.1 1 1 1 2 2 2 0 Kinetochore component, CENP-R FBPase PF00316.20 ORY37483.1 - 0.045 13.2 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain zf-C2H2_4 PF13894.6 ORY37484.1 - 3.4 8.8 5.6 2.4 9.2 0.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Mito_carr PF00153.27 ORY37485.1 - 0.00017 21.4 5.1 0.97 9.4 0.0 4.4 5 1 1 6 6 6 3 Mitochondrial carrier protein Pox_A_type_inc PF04508.12 ORY37486.1 - 0.029 14.2 0.6 0.064 13.1 0.0 1.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat SPX PF03105.19 ORY37486.1 - 0.52 10.2 6.0 2.4 8.0 6.0 1.9 1 1 0 1 1 1 0 SPX domain LRR_4 PF12799.7 ORY37487.1 - 0.025 15.0 5.3 0.027 14.9 3.5 2.1 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) DDDD PF10161.9 ORY37487.1 - 0.086 12.6 1.6 0.24 11.2 1.6 1.7 1 0 0 1 1 1 0 Putative mitochondrial precursor protein LRR_1 PF00560.33 ORY37487.1 - 0.37 11.5 3.3 4.8 8.1 0.8 3.4 2 0 0 2 2 2 0 Leucine Rich Repeat LRR_8 PF13855.6 ORY37487.1 - 1.4 8.7 4.6 6.1 6.7 3.4 2.5 1 1 1 2 2 2 0 Leucine rich repeat GATA PF00320.27 ORY37488.1 - 5.1e-12 45.2 4.3 5.1e-12 45.2 4.3 1.9 2 0 0 2 2 2 1 GATA zinc finger MerR-DNA-bind PF09278.11 ORY37488.1 - 0.14 12.7 0.6 4 8.0 0.0 2.4 2 0 0 2 2 2 0 MerR, DNA binding zf-C2H2 PF00096.26 ORY37488.1 - 0.15 12.5 5.9 2.1 9.0 0.3 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type NmrA PF05368.13 ORY37489.1 - 6e-22 78.3 2.3 1.7e-21 76.9 2.2 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY37489.1 - 1.4e-15 57.7 0.5 2.9e-15 56.6 0.4 1.7 1 1 1 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 ORY37489.1 - 0.00015 20.9 0.0 0.00026 20.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORY37489.1 - 0.001 18.3 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 ORY37489.1 - 0.0032 17.0 0.4 0.0094 15.4 0.4 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 ORY37489.1 - 0.0053 16.9 0.1 0.014 15.5 0.1 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 ORY37489.1 - 0.0073 16.2 0.5 0.013 15.5 0.5 1.3 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 ORY37489.1 - 0.0099 16.3 0.1 0.019 15.4 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DUF4088 PF13317.6 ORY37489.1 - 0.15 11.6 0.2 0.29 10.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) Phi_1 PF04674.12 ORY37490.1 - 6.4e-19 68.3 1.7 1.4e-18 67.2 1.7 1.5 1 1 0 1 1 1 1 Phosphate-induced protein 1 conserved region GATA PF00320.27 ORY37491.1 - 4.7e-13 48.5 5.6 8.2e-13 47.7 5.6 1.4 1 0 0 1 1 1 1 GATA zinc finger SDA1 PF05285.12 ORY37493.1 - 0.011 15.2 14.1 0.019 14.4 14.1 1.4 1 1 0 1 1 1 0 SDA1 PIG-P PF08510.12 ORY37493.1 - 0.68 9.9 2.7 2.9 7.8 2.7 2.1 1 0 0 1 1 1 0 PIG-P Nop14 PF04147.12 ORY37493.1 - 1.1 7.4 12.3 1.7 6.8 12.3 1.2 1 0 0 1 1 1 0 Nop14-like family RXLR PF16810.5 ORY37493.1 - 1.8 9.0 3.9 6 7.3 3.9 1.9 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity GREB1 PF15782.5 ORY37493.1 - 2.1 5.3 6.6 3.2 4.7 6.6 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LRR_8 PF13855.6 ORY37494.1 - 6.8e-20 70.6 3.9 1e-08 34.8 0.4 3.5 4 0 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 ORY37494.1 - 1.4e-15 57.2 7.9 0.0066 16.8 0.0 5.0 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY37494.1 - 3.5e-05 23.5 13.8 0.42 10.8 0.0 6.2 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.33 ORY37494.1 - 5.4e-05 23.2 17.8 0.75 10.6 0.1 7.7 8 0 0 8 8 8 2 Leucine Rich Repeat F-box PF00646.33 ORY37494.1 - 0.00049 19.9 0.0 0.0017 18.2 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY37494.1 - 0.0034 17.2 0.0 0.0096 15.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORY37494.1 - 0.021 14.7 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 F-box zf-C2H2 PF00096.26 ORY37495.1 - 1.2e-06 28.6 12.6 0.00096 19.5 4.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_8 PF15909.5 ORY37495.1 - 0.0065 16.7 4.1 0.0065 16.7 4.1 2.5 2 1 0 2 2 2 1 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 ORY37495.1 - 0.058 13.9 0.5 0.058 13.9 0.5 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY37495.1 - 0.21 12.5 0.2 0.21 12.5 0.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger ZF-HD_dimer PF04770.12 ORY37495.1 - 0.61 10.5 2.8 1.3 9.4 0.3 2.3 2 0 0 2 2 2 0 ZF-HD protein dimerisation region NOA36 PF06524.12 ORY37495.1 - 2.8 7.2 10.2 5.8 6.1 10.2 1.5 1 0 0 1 1 1 0 NOA36 protein zf-C2H2 PF00096.26 ORY37496.1 - 3.9e-11 42.7 11.8 4.2e-05 23.8 0.6 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY37496.1 - 2.2e-06 28.0 9.4 0.0035 18.1 0.1 2.5 2 1 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY37496.1 - 2.1e-05 24.7 11.5 0.00016 22.0 0.4 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY37496.1 - 0.00066 19.9 2.9 0.089 13.1 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 ORY37496.1 - 0.001 18.9 0.2 0.0014 18.4 0.2 1.4 1 0 0 1 1 1 1 GAGA factor zf-C2H2_8 PF15909.5 ORY37496.1 - 0.0017 18.6 0.4 0.0062 16.8 0.4 1.7 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-met PF12874.7 ORY37496.1 - 0.0019 18.5 2.9 1.8 9.1 0.0 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf_ZIC PF18366.1 ORY37496.1 - 0.011 15.9 4.3 0.27 11.3 3.1 2.2 1 1 1 2 2 2 0 Zic proteins zinc finger domain zf-C2H2_aberr PF17017.5 ORY37496.1 - 0.044 13.9 0.4 1.5 9.0 0.0 2.0 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_6 PF13912.6 ORY37496.1 - 0.16 12.0 0.0 0.16 12.0 0.0 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY37497.1 - 4.7e-08 33.1 9.2 0.00045 20.5 3.0 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY37497.1 - 1.5e-06 28.5 8.3 0.0014 19.3 2.6 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-LYAR PF08790.11 ORY37497.1 - 0.0022 17.9 0.9 0.009 15.9 0.3 2.1 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger FOXP-CC PF16159.5 ORY37497.1 - 0.0073 16.9 1.0 0.04 14.6 0.0 1.9 1 1 1 2 2 2 1 FOXP coiled-coil domain Ogr_Delta PF04606.12 ORY37497.1 - 0.013 15.5 1.3 2 8.4 0.1 2.1 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2_jaz PF12171.8 ORY37497.1 - 0.019 15.3 0.9 0.019 15.3 0.9 2.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY37497.1 - 0.023 15.1 1.9 3.6 8.1 0.8 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 ORY37497.1 - 0.09 12.9 4.2 1.2 9.3 4.1 2.2 1 1 0 1 1 1 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 ORY37497.1 - 0.13 12.8 0.3 0.13 12.8 0.3 3.2 2 1 1 3 3 3 0 Zinc-finger double domain TFIIS_C PF01096.18 ORY37497.1 - 0.2 11.5 3.9 0.39 10.6 0.5 2.1 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-C2H2_6 PF13912.6 ORY37497.1 - 2.2 8.4 10.4 1 9.4 4.9 2.8 2 2 0 2 2 2 0 C2H2-type zinc finger SUIM_assoc PF16619.5 ORY37498.1 - 0.039 14.0 14.1 0.74 9.9 2.0 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 ANAPC_CDC26 PF10471.9 ORY37498.1 - 7.3 7.5 15.9 3.9 8.4 3.2 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 LRR_6 PF13516.6 ORY37500.1 - 0.64 10.2 3.3 4.5 7.6 0.1 3.9 5 0 0 5 5 5 0 Leucine Rich repeat Kelch_6 PF13964.6 ORY37560.1 - 7.1e-09 35.7 11.7 0.013 15.8 0.2 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_5 PF13854.6 ORY37560.1 - 1.3e-05 25.1 7.7 0.068 13.2 0.0 5.2 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.6 ORY37560.1 - 0.00081 19.6 5.0 2.4 8.6 0.6 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY37560.1 - 0.0014 18.5 7.2 0.76 9.9 0.1 4.3 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 ORY37560.1 - 0.14 12.2 9.3 6.8 6.8 0.1 4.7 5 0 0 5 5 5 0 Galactose oxidase, central domain Retrotrans_gag PF03732.17 ORY37561.1 - 2e-05 24.8 0.3 5.2e-05 23.4 0.1 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4919 PF16266.5 ORY37561.1 - 0.036 14.0 0.1 0.076 13.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) DUF3524 PF12038.8 ORY37561.1 - 0.085 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3524) RVP_2 PF08284.11 ORY37562.1 - 0.00085 19.1 0.0 0.00092 19.0 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Phage-MuB_C PF09077.11 ORY37564.1 - 0.00052 19.8 0.1 0.46 10.4 0.0 3.5 2 0 0 2 2 2 2 Mu B transposition protein, C terminal SIR2_2 PF13289.6 ORY37564.1 - 0.14 12.2 0.0 0.81 9.8 0.0 2.3 2 0 0 2 2 2 0 SIR2-like domain HSV_VP16_C PF12149.8 ORY37564.1 - 0.25 11.4 3.6 3.4 7.8 0.1 2.7 2 0 0 2 2 2 0 Herpes simplex virus virion protein 16 C terminal Pkinase_Tyr PF07714.17 ORY37567.1 - 4.1e-42 144.3 0.0 6.8e-42 143.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORY37567.1 - 1.7e-39 135.8 0.0 2.6e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Sel1 PF08238.12 ORY37567.1 - 3.6e-16 59.3 6.5 2.9e-07 30.9 0.3 4.1 4 0 0 4 4 4 3 Sel1 repeat APH PF01636.23 ORY37567.1 - 0.00071 19.6 0.1 0.0017 18.4 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY37567.1 - 0.0029 17.0 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY37567.1 - 0.01 14.8 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 ORY37567.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 ORY37568.1 - 1.3e-41 142.6 0.0 1.6e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORY37568.1 - 1.8e-39 135.7 0.0 2.3e-39 135.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 ORY37568.1 - 0.00019 20.8 0.0 0.00028 20.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY37568.1 - 0.00069 19.6 1.9 0.0022 17.9 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY37568.1 - 0.0012 17.9 0.0 0.0017 17.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY37568.1 - 0.0093 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Sel1 PF08238.12 ORY37569.1 - 4.9e-20 71.5 4.9 3.3e-11 43.5 0.9 2.3 2 0 0 2 2 2 2 Sel1 repeat TPR_6 PF13174.6 ORY37569.1 - 0.00066 20.2 1.6 0.0013 19.2 0.2 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY37569.1 - 0.13 12.9 3.4 0.63 10.7 2.3 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY37569.1 - 0.22 11.7 3.0 34 4.9 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 ORY37570.1 - 1.2e-41 142.7 0.0 1.5e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORY37570.1 - 2e-40 138.8 0.0 2.6e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 ORY37570.1 - 3.1e-05 24.0 0.0 6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY37570.1 - 8.6e-05 22.0 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY37570.1 - 0.00065 18.8 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY37570.1 - 0.063 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sel1 PF08238.12 ORY37571.1 - 4.5e-16 58.9 0.4 4e-06 27.3 0.0 3.2 3 0 0 3 3 3 2 Sel1 repeat TPR_6 PF13174.6 ORY37571.1 - 0.07 13.8 1.1 2.9 8.7 0.3 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY37571.1 - 0.1 13.3 0.2 3.8 8.2 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Cupin_2 PF07883.11 ORY37572.1 - 0.003 17.2 0.0 0.0069 16.1 0.0 1.5 1 0 0 1 1 1 1 Cupin domain EutQ PF06249.12 ORY37572.1 - 0.0083 15.9 0.6 0.053 13.3 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.12 ORY37572.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) LRR_4 PF12799.7 ORY37573.1 - 7.2e-09 35.8 5.3 1.9e-05 24.9 0.2 3.0 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY37573.1 - 1.9e-06 27.5 0.5 4e-06 26.5 0.5 1.6 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.33 ORY37573.1 - 0.0029 17.9 0.2 8.4 7.4 0.1 3.4 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.6 ORY37573.1 - 0.039 14.0 2.4 0.75 10.0 0.3 2.9 2 0 0 2 2 2 0 Leucine Rich repeat F-box-like PF12937.7 ORY37573.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 F-box-like PARM PF17061.5 ORY37573.1 - 1.8 8.6 71.8 2.9 8.0 71.8 1.3 1 0 0 1 1 1 0 PARM UPF0220 PF05255.11 ORY37574.1 - 7.8e-38 129.6 0.0 1e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) PIF1 PF05970.14 ORY37577.1 - 1.3e-08 34.4 0.0 3.4e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 PIF1-like helicase DUF4926 PF16277.5 ORY37577.1 - 0.00013 21.3 0.0 0.00021 20.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4926) SH3_13 PF18335.1 ORY37577.1 - 0.0003 20.6 0.0 0.00065 19.5 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain SBDS_C PF09377.10 ORY37577.1 - 0.0096 15.9 0.1 0.057 13.4 0.2 2.0 1 1 0 1 1 1 1 SBDS protein C-terminal domain DUF4692 PF15763.5 ORY37577.1 - 0.12 12.9 0.2 0.17 12.3 0.2 1.2 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) zf-HC5HC2H PF13771.6 ORY37580.1 - 0.081 13.2 1.8 0.3 11.3 1.8 1.9 1 0 0 1 1 1 0 PHD-like zinc-binding domain Sulfotransfer_3 PF13469.6 ORY37582.1 - 3.2e-27 96.3 0.0 3.1e-26 93.1 0.0 2.3 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 ORY37582.1 - 3.6e-06 26.6 0.2 6.2e-05 22.6 0.2 2.3 1 1 0 1 1 1 1 Sulfotransferase domain PUF PF00806.19 ORY37583.1 - 8.6e-43 141.7 5.7 4.7e-06 26.0 0.1 8.5 8 0 0 8 8 8 7 Pumilio-family RNA binding repeat CPL PF08144.11 ORY37583.1 - 0.0036 17.7 0.2 2.8 8.3 0.1 3.7 3 1 0 3 3 3 1 CPL (NUC119) domain Atg14 PF10186.9 ORY37583.1 - 0.0053 15.9 3.7 0.012 14.7 3.7 1.5 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Tho2 PF11262.8 ORY37583.1 - 0.039 13.2 3.0 0.071 12.3 3.0 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Methyltransf_22 PF13383.6 ORY37585.1 - 2.1e-14 53.7 0.1 2.5e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 ORY37585.1 - 1.2e-06 28.7 0.0 1.3e-06 28.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase FkbM domain WD40 PF00400.32 ORY37586.1 - 3.1e-14 53.1 4.7 0.00049 20.9 0.2 6.9 6 0 0 6 6 6 3 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 ORY37586.1 - 5.7e-06 25.9 21.9 5.7e-06 25.9 21.9 2.0 1 1 1 2 2 2 1 Zinc-ribbon, C4HC2 type ANAPC4_WD40 PF12894.7 ORY37586.1 - 1.3e-05 25.4 0.0 0.091 13.1 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Pkinase PF00069.25 ORY37588.1 - 3e-52 177.6 0.0 4e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY37588.1 - 1.4e-29 103.2 0.0 3.5e-29 101.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY37588.1 - 3.1e-06 26.7 0.0 5.1e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORY37588.1 - 0.045 13.7 0.0 0.27 11.1 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Poxvirus_B22R PF04395.12 ORY37588.1 - 0.063 12.8 0.8 0.15 11.6 0.8 1.5 1 0 0 1 1 1 0 Poxvirus B22R protein B PF02216.16 ORY37589.1 - 0.12 12.3 0.5 0.84 9.7 0.2 2.2 2 0 0 2 2 2 0 B domain Pkinase PF00069.25 ORY37590.1 - 8.5e-55 186.0 0.0 3e-54 184.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY37590.1 - 3.6e-31 108.4 0.0 5.1e-30 104.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY37590.1 - 7.1e-09 35.4 0.0 1.1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY37590.1 - 1.2e-05 25.3 0.0 0.033 14.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY37590.1 - 0.0096 14.7 0.1 0.0096 14.7 0.1 2.0 2 0 0 2 2 2 1 Fungal protein kinase RPAP3_C PF13877.6 ORY37590.1 - 0.13 12.8 0.2 2.1 9.0 0.0 2.7 3 1 0 3 3 3 0 Potential Monad-binding region of RPAP3 CENP-C_C PF11699.8 ORY37591.1 - 3.3e-21 75.3 3.0 5.8e-21 74.5 3.0 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 ORY37591.1 - 1.7e-07 30.9 0.1 8.1e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 ORY37591.1 - 0.005 16.5 0.8 0.015 15.0 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF861) SMBP PF16785.5 ORY37591.1 - 0.07 13.4 2.4 0.16 12.2 2.4 1.5 1 0 0 1 1 1 0 Small metal-binding protein AraC_binding PF02311.19 ORY37591.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain Sel1 PF08238.12 ORY37593.1 - 4e-69 227.5 17.1 2e-09 37.8 0.3 10.8 10 1 0 10 10 10 8 Sel1 repeat TPR_6 PF13174.6 ORY37593.1 - 1e-15 57.2 11.4 0.77 10.5 0.0 10.3 10 0 0 10 10 10 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY37593.1 - 1.3e-12 47.7 17.3 0.00093 19.4 1.6 6.0 3 1 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 ORY37593.1 - 1.1e-09 38.8 5.0 0.0089 16.7 0.0 6.4 6 3 4 10 10 10 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY37593.1 - 4e-05 24.0 4.7 1.3 9.6 0.0 6.1 6 1 1 7 7 7 1 Tetratricopeptide repeat DSRB PF10781.9 ORY37593.1 - 0.047 13.3 0.0 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Dextransucrase DSRB TPR_3 PF07720.12 ORY37593.1 - 0.36 10.9 2.5 7.4 6.7 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORY37593.1 - 0.57 10.7 6.0 19 5.9 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat UFC1 PF08694.11 ORY37593.1 - 5.6 6.6 7.2 8.9 5.9 0.0 3.5 3 1 1 4 4 4 0 Ubiquitin-fold modifier-conjugating enzyme 1 Pkinase PF00069.25 ORY37594.1 - 1e-33 116.8 0.0 1.2e-33 116.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY37594.1 - 1.4e-31 109.8 0.0 1.7e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY37594.1 - 0.00015 21.7 0.0 0.00024 21.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY37594.1 - 0.0071 15.3 0.0 0.01 14.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY37594.1 - 0.0078 15.6 0.0 0.01 15.2 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY37594.1 - 0.23 10.8 0.0 0.28 10.4 0.0 1.1 1 0 0 1 1 1 0 Kinase-like LRR_4 PF12799.7 ORY37595.1 - 3.4e-12 46.4 36.3 1.4e-06 28.5 2.1 6.1 4 1 1 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY37595.1 - 4.6e-06 26.3 35.7 3.9e-05 23.3 6.9 5.3 2 2 4 6 6 6 4 Leucine rich repeat LRR_1 PF00560.33 ORY37595.1 - 0.008 16.6 27.8 21 6.2 0.1 8.7 7 2 1 8 8 8 2 Leucine Rich Repeat LRR_6 PF13516.6 ORY37595.1 - 7.9 6.8 21.4 0.61 10.3 0.3 5.6 7 0 0 7 7 7 0 Leucine Rich repeat Sel1 PF08238.12 ORY37596.1 - 1.6e-32 111.2 12.6 6.7e-09 36.2 0.3 4.1 4 0 0 4 4 4 4 Sel1 repeat TPR_6 PF13174.6 ORY37596.1 - 2.1e-05 24.8 10.4 10 7.0 1.2 5.0 4 1 0 4 4 4 4 Tetratricopeptide repeat DUF4213 PF13938.6 ORY37596.1 - 0.077 13.2 0.4 1.9 8.8 0.1 3.0 1 1 1 2 2 2 0 Putative heavy-metal chelation TPR_1 PF00515.28 ORY37596.1 - 0.2 11.6 7.8 49 4.0 0.0 5.5 5 1 1 6 6 6 0 Tetratricopeptide repeat Mito_carr PF00153.27 ORY37597.1 - 1.3e-67 223.8 3.1 6.9e-22 77.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY37597.1 - 0.011 14.9 0.0 0.27 10.3 0.0 2.8 3 0 0 3 3 3 0 Gammaproteobacterial serine protease PT-VENN PF04829.13 ORY37597.1 - 1.1 9.4 0.0 1.1 9.4 0.0 2.9 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif Aldedh PF00171.22 ORY37598.1 - 1.6e-120 402.7 0.0 1.9e-120 402.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3606 PF12244.8 ORY37598.1 - 0.024 14.6 0.1 0.082 12.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) DUF2229 PF09989.9 ORY37598.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) EBP PF05241.12 ORY37600.1 - 7.7e-52 175.3 10.3 9e-52 175.1 10.3 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF2781 PF10914.8 ORY37600.1 - 0.044 14.2 9.1 0.1 13.0 9.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2781) EBP PF05241.12 ORY37601.1 - 4.4e-50 169.6 11.6 5.2e-50 169.4 11.6 1.0 1 0 0 1 1 1 1 Emopamil binding protein CoA_binding_3 PF13727.6 ORY37601.1 - 0.014 15.4 0.8 0.025 14.6 0.8 1.4 1 0 0 1 1 1 0 CoA-binding domain VIT1 PF01988.19 ORY37601.1 - 0.19 11.6 7.8 0.4 10.5 7.8 1.5 1 1 0 1 1 1 0 VIT family DUF2781 PF10914.8 ORY37601.1 - 1.1 9.7 14.1 6.2 7.2 13.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2781) FtsX PF02687.21 ORY37601.1 - 6.5 7.3 8.6 0.19 12.2 0.7 2.4 2 1 0 2 2 2 0 FtsX-like permease family Pkinase PF00069.25 ORY37602.1 - 6.1e-67 225.8 0.0 8.1e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY37602.1 - 4.1e-37 127.9 0.0 6.2e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 ORY37602.1 - 1e-15 57.4 24.3 3.1e-09 36.6 10.5 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Haspin_kinase PF12330.8 ORY37602.1 - 5.2e-05 22.4 0.2 7.4e-05 21.9 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORY37602.1 - 0.00084 18.7 0.0 0.018 14.4 0.0 2.1 1 1 0 2 2 2 1 Kinase-like C1_2 PF03107.16 ORY37602.1 - 0.19 12.0 20.9 1 9.7 9.1 2.6 2 0 0 2 2 2 0 C1 domain K_channel_TID PF07941.11 ORY37602.1 - 1.2 9.7 10.0 1.6 9.2 8.2 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Atrophin-1 PF03154.15 ORY37602.1 - 2.7 6.2 3.5 3.7 5.7 3.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family Cyclin_N PF00134.23 ORY37603.1 - 8e-11 41.8 0.0 2e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 ORY37603.1 - 0.084 13.3 0.1 0.16 12.3 0.1 1.7 1 1 0 1 1 1 0 Cyclin C-terminal domain TFIIB PF00382.19 ORY37603.1 - 0.18 11.9 0.2 0.35 10.9 0.2 1.4 1 0 0 1 1 1 0 Transcription factor TFIIB repeat CLAMP PF14769.6 ORY37604.1 - 2.8e-07 30.9 0.0 5.4e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 HET PF06985.11 ORY37605.1 - 0.00066 20.0 0.1 0.00066 20.0 0.1 2.8 2 1 1 3 3 3 1 Heterokaryon incompatibility protein (HET) RRP36 PF06102.12 ORY37605.1 - 0.026 14.5 1.5 0.039 13.9 1.5 1.2 1 0 0 1 1 1 0 rRNA biogenesis protein RRP36 GCR PF02155.15 ORY37605.1 - 0.068 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Glucocorticoid receptor eIF-4B PF06273.11 ORY37605.1 - 3.8 6.5 5.2 5.5 5.9 5.2 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B p450 PF00067.22 ORY37606.1 - 9.5e-60 202.6 0.1 1.1e-59 202.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 IDEAL PF08858.10 ORY37606.1 - 9.5 6.1 5.6 23 4.8 0.5 3.4 3 0 0 3 3 3 0 IDEAL domain RRM_1 PF00076.22 ORY37608.1 - 4.1e-43 145.1 2.4 2.7e-19 68.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 ORY37608.1 - 4.3e-15 56.6 2.9 4.3e-15 56.6 2.9 3.6 3 1 0 3 3 3 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 ORY37608.1 - 4.9e-09 35.9 0.1 0.0082 16.0 0.0 3.4 3 0 0 3 3 3 3 Occluded RNA-recognition motif RRM_3 PF08777.11 ORY37608.1 - 5.1e-05 23.3 10.4 0.00086 19.3 0.0 4.0 4 0 0 4 4 4 2 RNA binding motif Nup35_RRM_2 PF14605.6 ORY37608.1 - 0.014 15.3 0.2 8.2 6.5 0.1 3.2 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 ORY37608.1 - 0.026 14.1 0.2 6.1 6.5 0.0 2.9 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PMT PF02366.18 ORY37609.1 - 7.1e-58 196.1 20.1 7.1e-58 196.1 20.1 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORY37609.1 - 1.7e-33 115.9 14.8 1.7e-33 115.9 14.8 2.0 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORY37609.1 - 3.6e-13 49.8 0.1 7.4e-13 48.8 0.1 1.5 1 1 0 1 1 1 1 MIR domain Glyco_hydro_26 PF02156.15 ORY37611.1 - 2.4e-06 27.2 0.5 3.5e-06 26.7 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 AJAP1_PANP_C PF15298.6 ORY37611.1 - 0.46 10.7 6.5 0.73 10.0 6.5 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Pkinase PF00069.25 ORY37612.1 - 4.1e-63 213.2 0.1 4.7e-63 213.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY37612.1 - 3.8e-32 111.6 0.0 4.3e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY37612.1 - 3.9e-08 33.0 0.0 2.1e-07 30.6 0.0 1.9 1 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 ORY37612.1 - 1.1e-05 25.2 0.1 0.12 12.0 0.0 2.1 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 ORY37612.1 - 0.0017 17.8 0.6 0.0035 16.7 0.6 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORY37612.1 - 0.054 13.1 0.9 0.11 12.1 0.9 1.4 1 1 0 1 1 1 0 RIO1 family APH PF01636.23 ORY37612.1 - 0.093 12.6 0.1 0.97 9.3 0.0 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY37612.1 - 0.13 11.0 0.1 0.42 9.3 0.1 1.7 1 1 1 2 2 2 0 Fungal protein kinase CAML PF14963.6 ORY37613.1 - 3.2 7.8 7.6 2.6 8.1 0.2 2.3 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand PP2C PF00481.21 ORY37615.1 - 2.1e-13 50.5 0.0 6.5e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Protein phosphatase 2C EOS1 PF12326.8 ORY37615.1 - 3.7 7.5 4.7 10 6.0 0.0 2.5 2 0 0 2 2 2 0 N-glycosylation protein DUF572 PF04502.13 ORY37615.1 - 3.9 7.0 19.2 5.2 6.6 9.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) BUD22 PF09073.10 ORY37615.1 - 9 5.5 37.2 5.9 6.1 18.3 2.1 2 0 0 2 2 2 0 BUD22 LRRCT PF01463.24 ORY37616.1 - 0.2 12.3 0.6 0.75 10.5 0.0 2.3 2 0 0 2 2 2 0 Leucine rich repeat C-terminal domain Methyltransf_22 PF13383.6 ORY37617.1 - 3.7e-14 52.9 0.1 4.5e-14 52.6 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 ORY37617.1 - 6.4e-07 29.5 0.0 8.2e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain zf-MYND PF01753.18 ORY37618.1 - 1.8e-07 31.1 15.5 3.2e-07 30.3 15.5 1.4 1 0 0 1 1 1 1 MYND finger FAM70 PF14967.6 ORY37618.1 - 0.6 9.5 6.2 1.3 8.4 6.2 1.5 1 0 0 1 1 1 0 FAM70 protein TFIIA PF03153.13 ORY37618.1 - 1.2 9.1 14.4 1.3 8.9 6.9 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3439 PF11921.8 ORY37618.1 - 4.1 7.4 8.8 23 5.0 8.8 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) F-box PF00646.33 ORY37619.1 - 0.025 14.5 2.4 0.092 12.7 0.3 2.8 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.7 ORY37619.1 - 0.036 13.9 0.5 0.036 13.9 0.5 2.6 3 0 0 3 3 3 0 F-box-like Usp PF00582.26 ORY37619.1 - 0.04 14.4 0.0 0.16 12.5 0.0 1.9 2 0 0 2 2 2 0 Universal stress protein family LRR_8 PF13855.6 ORY37620.1 - 1.6e-19 69.4 21.0 3.5e-09 36.3 4.0 2.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY37620.1 - 3.7e-08 33.5 7.0 0.00019 21.8 0.3 3.3 2 2 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY37620.1 - 3.8e-05 23.6 11.9 0.54 11.0 0.0 4.5 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.6 ORY37620.1 - 0.066 13.3 1.8 4.5 7.6 0.2 3.3 3 0 0 3 3 3 0 Leucine Rich repeat PHD PF00628.29 ORY37621.1 - 5.5e-12 45.4 6.2 2.3e-11 43.4 6.2 2.1 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 ORY37621.1 - 0.021 14.4 1.3 0.061 12.9 1.3 1.8 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.6 ORY37621.1 - 0.025 14.8 5.6 0.025 14.8 3.1 2.3 2 0 0 2 2 2 0 PHD-like zinc-binding domain DUF3605 PF12239.8 ORY37621.1 - 0.1 12.9 0.2 0.33 11.3 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3605) zf-HC5HC2H_2 PF13832.6 ORY37621.1 - 0.27 11.4 4.9 0.33 11.1 2.3 2.4 2 0 0 2 2 2 0 PHD-zinc-finger like domain AMP-binding PF00501.28 ORY37622.1 - 1.5e-55 188.5 0.0 6.5e-27 94.2 0.0 2.2 1 1 1 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 ORY37622.1 - 1.4e-27 96.5 0.1 2.1e-27 95.9 0.1 1.1 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 ORY37622.1 - 2.6e-09 37.3 0.0 6.2e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Condensation PF00668.20 ORY37624.1 - 1.2e-27 96.8 0.3 2e-27 96.0 0.3 1.3 1 1 0 1 1 1 1 Condensation domain DAD PF02109.16 ORY37624.1 - 0.015 15.6 0.3 0.03 14.6 0.3 1.6 1 0 0 1 1 1 0 DAD family DAO PF01266.24 ORY37625.1 - 9.7e-72 242.5 0.0 1.3e-71 242.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fer2_BFD PF04324.15 ORY37625.1 - 4.2e-16 59.0 1.5 1.2e-15 57.6 1.5 1.8 1 0 0 1 1 1 1 BFD-like [2Fe-2S] binding domain Pyr_redox_2 PF07992.14 ORY37625.1 - 2.7e-08 33.4 0.0 5.3e-05 22.6 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY37625.1 - 5e-06 26.6 0.4 1.3e-05 25.4 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY37625.1 - 3.1e-05 24.5 1.5 0.00019 21.9 0.9 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 ORY37625.1 - 0.00017 20.3 0.1 0.00026 19.7 0.1 1.2 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) 2-Hacid_dh_C PF02826.19 ORY37625.1 - 0.00094 18.6 0.1 0.0022 17.4 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 ORY37625.1 - 0.001 18.4 0.3 0.0015 17.8 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 ORY37625.1 - 0.0019 17.5 0.7 0.0035 16.6 0.7 1.3 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.18 ORY37625.1 - 0.0077 16.1 0.4 0.013 15.4 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 ORY37625.1 - 0.012 14.9 0.4 0.17 11.1 0.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 ORY37625.1 - 0.043 14.1 0.3 0.091 13.0 0.3 1.6 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.12 ORY37625.1 - 0.044 12.8 0.4 0.07 12.2 0.4 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 ORY37625.1 - 0.06 12.6 0.7 0.13 11.5 0.7 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 ORY37625.1 - 0.07 13.4 0.6 0.15 12.4 0.6 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 ORY37625.1 - 0.097 12.7 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase XdhC_C PF13478.6 ORY37625.1 - 0.1 13.1 0.0 0.26 11.8 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain adh_short PF00106.25 ORY37626.1 - 1.3e-32 112.9 0.6 7.5e-31 107.1 0.6 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY37626.1 - 4.8e-26 91.8 0.4 1.4e-24 87.0 0.4 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY37626.1 - 3.8e-08 33.5 0.0 5.9e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY37626.1 - 3.2e-05 23.5 0.0 0.00014 21.4 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY37626.1 - 0.035 14.0 0.6 0.39 10.6 0.6 2.2 1 1 0 1 1 1 0 NAD(P)H-binding CCB2_CCB4 PF11152.8 ORY37626.1 - 0.12 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 7tm_2 PF00002.24 ORY37627.1 - 1.4e-07 31.0 12.7 1.9e-07 30.6 12.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 ORY37627.1 - 1.5e-07 31.0 10.6 4.1e-07 29.6 10.6 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 ORY37627.1 - 0.024 14.4 18.6 0.1 12.4 18.6 2.0 1 1 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 DUF962 PF06127.11 ORY37627.1 - 2.7 8.2 7.0 1.2 9.3 0.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF962) ECH_1 PF00378.20 ORY37628.1 - 4.1e-85 285.1 1.6 4.6e-85 284.9 1.6 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY37628.1 - 1.4e-36 126.7 3.4 2.6e-33 115.9 0.8 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 ORY37628.1 - 0.0072 16.3 0.4 2.8 7.9 0.0 2.4 2 0 0 2 2 2 2 Peptidase family S49 NADH-u_ox-rdase PF10785.9 ORY37629.1 - 1.4e-11 44.9 0.2 1.6e-11 44.7 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Acetyltransf_9 PF13527.7 ORY37630.1 - 7.3e-14 52.0 0.0 1.3e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_17 PF17668.1 ORY37630.1 - 4.7e-12 46.7 0.0 8.5e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SCP2_2 PF13530.6 ORY37630.1 - 7.6e-07 29.5 0.0 1.3e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Sterol carrier protein domain Acetyltransf_10 PF13673.7 ORY37630.1 - 0.031 14.2 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY37630.1 - 0.045 14.0 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY37630.1 - 0.059 13.8 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY37630.1 - 0.11 12.4 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_17 PF17668.1 ORY37631.1 - 9.2e-13 49.0 0.0 2.5e-12 47.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY37631.1 - 1.3e-12 47.9 0.1 7e-12 45.5 0.0 2.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain SCP2_2 PF13530.6 ORY37631.1 - 8e-06 26.2 0.0 1.6e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Sterol carrier protein domain SCP2 PF02036.17 ORY37631.1 - 0.016 15.6 0.0 0.037 14.5 0.0 1.6 1 0 0 1 1 1 0 SCP-2 sterol transfer family Acetyltransf_7 PF13508.7 ORY37631.1 - 0.027 14.9 0.0 0.062 13.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY37631.1 - 0.028 14.4 0.0 0.093 12.7 0.0 1.9 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_1 PF00583.25 ORY37631.1 - 0.15 12.3 0.0 0.42 10.9 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Tyrosinase PF00264.20 ORY37632.1 - 2.9e-33 116.0 2.8 7.2e-33 114.7 2.8 1.7 1 1 0 1 1 1 1 Common central domain of tyrosinase Ricin_B_lectin PF00652.22 ORY37632.1 - 1.5e-10 41.4 0.7 1.5e-10 41.4 0.7 1.9 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 ORY37632.1 - 0.00063 20.4 0.1 0.0025 18.5 0.1 2.0 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 ORY37632.1 - 0.013 15.1 0.5 0.23 11.0 0.1 2.3 2 0 0 2 2 2 0 Cytolethal distending toxin A/C domain Vac_ImportDeg PF09783.9 ORY37633.1 - 4e-46 156.8 9.9 1.2e-42 145.5 6.9 2.0 1 1 1 2 2 2 2 Vacuolar import and degradation protein AMP-binding PF00501.28 ORY37634.1 - 1.3e-17 63.6 0.0 6.5e-17 61.2 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme NAD_Gly3P_dh_N PF01210.23 ORY37634.1 - 0.083 12.9 0.5 0.16 11.9 0.5 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Glyco_transf_21 PF13506.6 ORY37635.1 - 5.6e-26 91.1 0.0 1.4e-25 89.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 ORY37635.1 - 5.5e-11 42.8 0.0 1.3e-10 41.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ORY37636.1 - 2.9e-35 121.3 0.0 4.2e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 ORY37636.1 - 2.7e-14 53.6 0.0 4.1e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORY37636.1 - 3.7e-06 27.0 1.6 1.1e-05 25.5 1.6 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORY37636.1 - 0.028 14.2 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORY37637.1 - 4.2e-40 137.0 0.0 5.3e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 ORY37637.1 - 7.1e-17 62.1 0.0 1.8e-16 60.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORY37637.1 - 8.4e-09 35.6 3.2 1.2e-08 35.1 3.2 1.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 ORY37637.1 - 0.0071 16.2 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 UCH PF00443.29 ORY37639.1 - 1.2e-48 165.9 0.0 1.7e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 ORY37639.1 - 2.7e-39 134.9 0.0 5.7e-39 133.9 0.0 1.5 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 ORY37639.1 - 5.8e-20 72.1 0.0 2.1e-19 70.3 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 ORY37639.1 - 0.0008 19.6 0.0 0.0025 17.9 0.0 1.9 1 0 0 1 1 1 1 MATH domain USP7_C2 PF14533.6 ORY37640.1 - 5.4e-23 81.8 0.0 6e-23 81.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal YabA PF06156.13 ORY37641.1 - 9.4 6.9 6.3 1.2 9.8 0.6 2.5 3 0 0 3 3 3 0 Initiation control protein YabA Pox_D5 PF03288.16 ORY37642.1 - 0.032 14.7 0.0 0.07 13.6 0.0 1.5 1 0 0 1 1 1 0 Poxvirus D5 protein-like AAA_26 PF13500.6 ORY37644.1 - 2.6e-11 43.7 0.0 4.2e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain BATS PF06968.13 ORY37645.1 - 1.3e-18 66.9 0.1 2.6e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 ORY37645.1 - 7e-10 39.5 0.0 1.7e-09 38.3 0.0 1.7 2 0 0 2 2 2 1 Radical SAM superfamily PET117 PF15786.5 ORY37646.1 - 4.3e-11 42.9 0.1 5.7e-11 42.5 0.1 1.2 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial DUF4337 PF14235.6 ORY37647.1 - 5.2 7.2 8.3 6.1 6.9 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) WRC PF08879.10 ORY37648.1 - 0.074 12.8 0.4 0.13 12.0 0.4 1.4 1 0 0 1 1 1 0 WRC Proteasome PF00227.26 ORY37649.1 - 1.5e-56 190.9 0.0 2e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORY37649.1 - 1.5e-13 50.1 0.1 2.7e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Cpn60_TCP1 PF00118.24 ORY37650.1 - 7.3e-85 285.4 17.8 2.4e-49 168.3 9.7 5.2 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family VIT1 PF01988.19 ORY37652.1 - 1e-25 90.9 2.0 1.1e-25 90.8 2.0 1.0 1 0 0 1 1 1 1 VIT family DUF1129 PF06570.11 ORY37652.1 - 0.45 10.0 2.1 0.21 11.0 0.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Nucleopor_Nup85 PF07575.13 ORY37653.1 - 1.2e-52 179.3 2.9 1.1e-51 176.1 2.9 1.9 1 1 0 1 1 1 1 Nup85 Nucleoporin Nic96 PF04097.14 ORY37653.1 - 9.1e-05 21.1 1.3 0.00079 18.0 0.5 2.1 2 0 0 2 2 2 1 Nup93/Nic96 NRDE-2 PF08424.10 ORY37653.1 - 0.087 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference LRR_8 PF13855.6 ORY37654.1 - 1.6e-11 43.8 6.3 6.9e-09 35.3 0.2 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 ORY37654.1 - 1.3e-09 38.2 3.2 0.00064 20.1 0.1 3.3 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY37654.1 - 0.00014 21.9 9.7 4.1 8.3 0.3 6.0 5 1 1 6 6 6 2 Leucine Rich Repeat F-box PF00646.33 ORY37654.1 - 0.00044 20.1 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY37654.1 - 0.0046 16.8 0.0 0.02 14.8 0.0 2.1 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 ORY37654.1 - 0.063 13.4 4.6 10 6.5 0.4 4.3 4 0 0 4 4 4 0 Leucine Rich repeat Scs3p PF10261.9 ORY37655.1 - 5.7e-41 140.7 17.7 9.3e-33 113.8 3.6 2.0 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM NOA36 PF06524.12 ORY37656.1 - 0.18 11.1 3.3 0.18 11.1 3.3 1.1 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 ORY37656.1 - 4.1 7.8 9.9 4.7 7.7 9.3 1.5 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.32 ORY37657.1 - 8.4e-57 187.8 36.2 4.7e-07 30.4 0.0 12.8 11 1 0 11 11 11 8 WD domain, G-beta repeat Utp13 PF08625.11 ORY37657.1 - 1.5e-44 151.3 4.6 2.7e-44 150.5 4.6 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 ORY37657.1 - 2.9e-21 75.6 11.6 0.0046 17.2 0.0 9.5 2 2 8 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain NT-C2 PF10358.9 ORY37657.1 - 3.3e-14 52.8 0.0 2.4e-11 43.5 0.0 2.6 2 0 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins Nup160 PF11715.8 ORY37657.1 - 6e-09 35.1 12.8 0.23 10.1 0.3 6.8 3 1 3 6 6 6 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 ORY37657.1 - 6.3e-07 28.5 6.9 0.37 9.5 0.0 6.0 1 1 4 5 5 5 3 Nup133 N terminal like Cytochrom_D1 PF02239.16 ORY37657.1 - 1.1e-05 24.2 0.1 2.5e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Cytochrome D1 heme domain WD40_like PF17005.5 ORY37657.1 - 0.00081 18.8 3.3 14 4.8 0.0 5.2 5 1 1 6 6 6 1 WD40-like domain BBS2_Mid PF14783.6 ORY37657.1 - 0.019 15.0 3.3 4.7 7.3 0.0 5.3 6 2 1 7 7 7 0 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 ORY37657.1 - 0.034 13.1 9.6 2.5 6.9 0.1 4.5 3 2 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HPS3_N PF14761.6 ORY37657.1 - 0.11 12.0 0.3 4.9 6.6 0.1 3.2 4 0 0 4 4 4 0 Hermansky-Pudlak syndrome 3 MRP_L53 PF10780.9 ORY37658.1 - 1.3e-06 28.4 0.1 2.3e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 HLH PF00010.26 ORY37659.1 - 2.8e-09 36.8 0.3 7.2e-09 35.5 0.3 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SPAN PF02510.14 ORY37659.1 - 0.011 15.0 2.3 0.011 15.0 2.3 1.6 2 0 0 2 2 2 0 Surface presentation of antigens protein Acetyltransf_2 PF00797.17 ORY37660.1 - 4.7e-31 108.4 0.0 5.5e-31 108.2 0.0 1.0 1 0 0 1 1 1 1 N-acetyltransferase VP4_haemagglut PF00426.18 ORY37660.1 - 0.16 12.2 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) Concanavalin-like domain KTI12 PF08433.10 ORY37661.1 - 0.00061 19.3 0.0 0.001 18.6 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_14 PF13173.6 ORY37661.1 - 0.0019 18.3 0.0 0.004 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY37661.1 - 0.0036 17.6 0.0 0.38 11.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 ORY37661.1 - 0.0088 16.4 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 ORY37661.1 - 0.013 15.9 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 ORY37661.1 - 0.04 13.8 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 ORY37661.1 - 0.1 13.1 0.0 0.36 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ORY37661.1 - 0.12 12.5 0.0 0.66 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ORY37661.1 - 0.17 11.6 0.0 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Sterol-sensing PF12349.8 ORY37662.1 - 1.7e-49 167.6 10.2 2.5e-49 167.1 10.2 1.2 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 ORY37662.1 - 2.8e-20 72.0 16.1 3.5e-20 71.7 16.1 1.0 1 0 0 1 1 1 1 Patched family YrhC PF14143.6 ORY37662.1 - 4.3 7.5 10.2 0.46 10.6 4.6 2.1 2 0 0 2 2 2 0 YrhC-like protein TMEM223 PF14640.6 ORY37663.1 - 5.4e-14 52.7 0.0 1.3e-13 51.4 0.0 1.6 1 1 0 1 1 1 1 Transmembrane protein 223 DUF3918 PF13056.6 ORY37663.1 - 0.048 13.3 0.9 0.17 11.5 0.3 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3918) Megourin PF17560.2 ORY37663.1 - 0.21 11.9 0.0 0.38 11.0 0.0 1.4 1 0 0 1 1 1 0 Aphid Megourins Hemerythrin PF01814.23 ORY37664.1 - 9.8e-10 39.2 0.5 1.5e-09 38.6 0.5 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Hemerythrin PF01814.23 ORY37665.1 - 0.00018 22.1 0.0 0.00022 21.8 0.0 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain dCMP_cyt_deam_1 PF00383.23 ORY37666.1 - 7.1e-08 32.3 0.1 1.1e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Amidohydro_1 PF01979.20 ORY37667.1 - 4.9e-13 49.1 0.1 1.7e-08 34.2 0.1 3.5 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 ORY37667.1 - 8.8e-12 45.2 11.3 4.2e-06 26.5 0.2 4.0 4 1 0 4 4 4 3 Amidohydrolase family FAM183 PF14886.6 ORY37668.1 - 0.00012 22.8 0.1 0.00063 20.5 0.1 2.0 2 0 0 2 2 2 1 FAM183A and FAM183B related FA_desaturase PF00487.24 ORY37669.1 - 4.3e-34 118.5 17.1 7.2e-34 117.8 17.1 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 ORY37669.1 - 1.6e-11 44.2 0.0 3.7e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Caps_synth_CapC PF14102.6 ORY37669.1 - 0.42 11.0 3.2 0.16 12.4 0.4 1.7 2 0 0 2 2 2 0 Capsule biosynthesis CapC CDC24_OB3 PF17244.2 ORY37670.1 - 7.9e-24 84.6 0.0 2.3e-23 83.1 0.0 1.7 2 0 0 2 2 2 1 Cell division control protein 24, OB domain 3 CDC24_OB2 PF17245.2 ORY37670.1 - 2.3e-10 41.2 0.2 4.6e-10 40.2 0.2 1.5 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 2 CDC24_OB1 PF17246.2 ORY37670.1 - 1e-08 35.3 0.1 2.1e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 1 REPA_OB_2 PF16900.5 ORY37670.1 - 1.4e-05 25.0 0.0 0.022 14.7 0.0 2.6 2 0 0 2 2 2 2 Replication protein A OB domain adh_short PF00106.25 ORY37671.1 - 3.5e-24 85.4 0.0 3.4e-22 78.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY37671.1 - 2.1e-16 60.2 0.0 7e-13 48.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY37671.1 - 2.7e-10 40.5 0.0 3.7e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 ORY37672.1 - 2.8e-27 95.4 0.3 4.2e-26 91.6 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY37672.1 - 2.4e-21 76.4 0.1 1.5e-19 70.5 0.1 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY37672.1 - 2.1e-07 31.0 0.1 2.8e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY37672.1 - 7.2e-07 28.9 0.0 8.9e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 ORY37672.1 - 0.0022 17.3 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Eno-Rase_NADH_b PF12242.8 ORY37672.1 - 0.028 14.2 0.1 0.059 13.1 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.15 ORY37672.1 - 0.065 12.3 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein YjeF_N PF03853.15 ORY37672.1 - 0.071 13.0 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus RmlD_sub_bind PF04321.17 ORY37672.1 - 0.11 11.6 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain GIT_SHD PF08518.11 ORY37675.1 - 2.7e-21 74.8 0.6 2.2e-10 39.9 0.5 2.4 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 ORY37675.1 - 1.1e-07 32.0 4.8 2e-07 31.1 0.1 3.0 2 1 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term FAM184 PF15665.5 ORY37675.1 - 0.0011 18.8 14.0 0.0011 18.8 14.0 2.1 3 0 0 3 3 3 1 Family with sequence similarity 184, A and B MPS2 PF17060.5 ORY37675.1 - 0.0011 18.3 1.8 0.0021 17.4 1.8 1.5 1 0 0 1 1 1 1 Monopolar spindle protein 2 FPP PF05911.11 ORY37675.1 - 0.0024 16.2 11.3 0.041 12.1 8.9 2.3 2 0 0 2 2 2 1 Filament-like plant protein, long coiled-coil Uso1_p115_C PF04871.13 ORY37675.1 - 0.022 15.1 9.8 0.022 15.1 9.8 4.6 5 0 0 5 5 5 0 Uso1 / p115 like vesicle tethering protein, C terminal region UPF0184 PF03670.13 ORY37675.1 - 0.12 12.8 4.3 2.6 8.5 0.0 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0184) Sec34 PF04136.15 ORY37675.1 - 0.17 11.8 7.7 0.16 11.9 4.4 2.5 2 0 0 2 2 2 0 Sec34-like family GIT_CC PF16559.5 ORY37675.1 - 0.31 11.0 5.7 0.17 11.7 0.3 3.1 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Fib_alpha PF08702.10 ORY37675.1 - 0.41 10.8 0.1 0.41 10.8 0.1 3.4 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family HAUS-augmin3 PF14932.6 ORY37675.1 - 0.48 10.0 15.7 0.33 10.5 13.3 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Spc7 PF08317.11 ORY37675.1 - 0.61 8.9 13.8 15 4.3 13.8 2.7 2 0 0 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 ORY37675.1 - 0.67 7.8 6.1 1.3 6.9 6.1 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Myb_DNA-bind_3 PF12776.7 ORY37675.1 - 1.3 10.1 5.7 11 7.1 0.2 3.2 2 1 0 3 3 2 0 Myb/SANT-like DNA-binding domain Laminin_I PF06008.14 ORY37675.1 - 1.9 8.1 21.9 0.15 11.7 10.5 3.6 3 1 1 4 4 4 0 Laminin Domain I DUF4164 PF13747.6 ORY37675.1 - 3.5 8.0 12.7 57 4.1 9.6 3.6 2 1 0 2 2 1 0 Domain of unknown function (DUF4164) STAT_alpha PF01017.20 ORY37675.1 - 4.1 7.3 16.3 20 5.0 6.1 3.0 2 1 1 3 3 3 0 STAT protein, all-alpha domain KxDL PF10241.9 ORY37675.1 - 4.4 7.6 16.8 0.13 12.5 5.6 3.9 4 1 1 5 5 3 0 Uncharacterized conserved protein DUF5595 PF18077.1 ORY37675.1 - 4.9 7.3 7.7 23 5.2 0.5 3.4 2 1 2 4 4 4 0 Domain of unknown function (DUF5595) TMF_DNA_bd PF12329.8 ORY37675.1 - 6.8 6.8 20.0 2.7 8.1 2.5 4.5 4 1 1 5 5 4 0 TATA element modulatory factor 1 DNA binding Tho2 PF11262.8 ORY37675.1 - 7.3 5.7 9.2 21 4.2 9.2 1.8 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF724 PF05266.14 ORY37675.1 - 7.8 6.3 10.9 20 4.9 10.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TMCO5 PF14992.6 ORY37675.1 - 8.5 5.9 14.0 20 4.6 14.0 1.5 1 0 0 1 1 1 0 TMCO5 family Fz PF01392.22 ORY37676.1 - 1.3e-07 32.2 2.2 3.5e-07 30.8 2.2 1.7 1 0 0 1 1 1 1 Fz domain Frizzled PF01534.17 ORY37676.1 - 0.0036 16.4 15.1 0.0036 16.4 15.1 2.2 2 0 0 2 2 2 2 Frizzled/Smoothened family membrane region Fz PF01392.22 ORY37677.1 - 0.0001 22.9 1.7 0.00021 21.9 1.7 1.4 1 0 0 1 1 1 1 Fz domain Frizzled PF01534.17 ORY37677.1 - 0.0031 16.6 17.5 0.0034 16.5 10.1 2.1 2 0 0 2 2 2 2 Frizzled/Smoothened family membrane region Pkinase PF00069.25 ORY37678.1 - 1.6e-38 132.6 0.0 1.8e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY37678.1 - 7.7e-16 58.2 0.0 9.1e-16 57.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY37678.1 - 0.016 14.5 0.0 0.017 14.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Aminotran_5 PF00266.19 ORY37679.1 - 5.1e-89 298.8 0.0 5.9e-89 298.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ORY37679.1 - 3e-08 33.3 0.0 3.2e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 ORY37679.1 - 8.5e-06 25.3 0.3 1.7e-05 24.4 0.1 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 ORY37679.1 - 0.00051 18.7 0.0 0.00073 18.2 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.19 ORY37679.1 - 0.0089 16.1 0.1 0.46 10.5 0.0 2.5 2 0 0 2 2 2 1 B12 binding domain Pyridoxal_deC PF00282.19 ORY37679.1 - 0.0093 14.7 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Glyco_hydro_47 PF01532.20 ORY37680.1 - 1.1e-107 360.8 0.0 1.5e-107 360.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PAC3 PF10178.9 ORY37681.1 - 8.6e-13 48.2 0.0 1.3e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 SMC_N PF02463.19 ORY37682.1 - 1.9e-26 92.9 11.9 8.6e-26 90.7 11.9 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 ORY37682.1 - 2.4e-21 76.2 0.1 7.4e-21 74.6 0.1 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 ORY37682.1 - 0.00015 21.7 0.0 0.00059 19.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system FlaC_arch PF05377.11 ORY37682.1 - 0.018 15.4 0.9 0.018 15.4 0.9 8.8 7 1 2 9 9 9 0 Flagella accessory protein C (FlaC) Retrotran_gag_2 PF14223.6 ORY37684.1 - 0.00037 20.2 0.0 0.00071 19.2 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type SAM_1 PF00536.30 ORY37685.1 - 5.4e-06 26.8 0.0 1.2e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 ORY37685.1 - 0.025 14.7 0.0 0.082 13.0 0.0 1.8 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Draxin PF15550.6 ORY37686.1 - 3.2 7.5 8.3 5.9 6.7 8.3 1.3 1 0 0 1 1 1 0 Draxin TPH PF13868.6 ORY37688.1 - 3.1 6.2 145.2 0.012 14.2 116.5 2.9 1 1 1 2 2 2 0 Trichohyalin-plectin-homology domain ATG2_CAD PF13329.6 ORY37689.1 - 5e-06 26.3 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 ORY37690.1 - 1.4e-29 102.2 3.1 3e-29 101.2 0.8 2.4 2 1 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 ORY37690.1 - 3.6e-06 26.9 0.0 0.0018 18.1 0.0 2.3 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal Arf PF00025.21 ORY37691.1 - 6.5e-66 221.1 0.1 7.1e-66 221.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORY37691.1 - 1.4e-13 51.1 0.0 2e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 ORY37691.1 - 8.5e-13 48.2 0.3 1.1e-08 34.7 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 ORY37691.1 - 3.7e-12 46.1 0.0 4.4e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 ORY37691.1 - 2.6e-11 43.4 0.0 3e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 ORY37691.1 - 2.5e-10 40.1 0.0 3.1e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORY37691.1 - 4.3e-08 33.2 0.0 5.9e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 ORY37691.1 - 0.093 12.5 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 ORY37691.1 - 0.14 12.7 0.0 0.22 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain WD40 PF00400.32 ORY37693.1 - 1.6e-43 145.8 12.4 1.3e-05 25.9 0.4 11.0 11 0 0 11 11 11 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY37693.1 - 4.7e-17 62.1 2.8 3.9e-06 27.1 0.0 6.5 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY37693.1 - 3.1e-07 29.7 1.7 0.14 11.1 0.0 4.8 4 1 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ORY37693.1 - 0.00011 21.7 0.1 3.4 6.9 0.0 3.6 2 1 0 3 3 3 2 WD40-like domain WD40_3 PF15911.5 ORY37693.1 - 0.003 17.5 0.1 30 4.7 0.0 4.2 3 1 1 4 4 4 0 WD domain, G-beta repeat IKI3 PF04762.12 ORY37693.1 - 0.0049 15.0 0.2 0.062 11.3 0.1 2.6 2 1 0 2 2 2 1 IKI3 family Frtz PF11768.8 ORY37693.1 - 0.16 10.3 0.0 21 3.3 0.0 2.7 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 ORY37693.1 - 0.17 11.9 1.0 13 5.9 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 ORY37693.1 - 2.5 8.7 7.6 5.6 7.6 0.0 4.7 6 0 0 6 6 6 0 PQQ-like domain AAA PF00004.29 ORY37694.1 - 2.3e-58 196.3 0.0 5e-44 149.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 ORY37694.1 - 6.6e-27 93.7 0.7 1.9e-26 92.3 0.7 1.9 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 ORY37694.1 - 2.5e-13 49.6 0.5 3.2e-07 30.1 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 ORY37694.1 - 2e-11 44.6 12.9 0.00033 21.1 0.5 5.7 4 2 1 6 6 5 3 AAA ATPase domain NACHT PF05729.12 ORY37694.1 - 5.1e-08 33.0 1.1 0.00062 19.7 0.1 3.7 3 1 0 3 3 3 2 NACHT domain AAA_33 PF13671.6 ORY37694.1 - 1e-07 32.2 0.0 0.011 15.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.14 ORY37694.1 - 4.9e-07 29.8 0.0 0.04 13.9 0.0 3.8 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ORY37694.1 - 1.4e-06 28.2 0.0 0.0015 18.3 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 ORY37694.1 - 5.9e-06 26.3 0.0 0.15 12.1 0.1 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 ORY37694.1 - 7.7e-06 26.2 2.3 0.12 12.7 0.2 4.4 2 2 2 4 4 4 2 AAA domain Viral_helicase1 PF01443.18 ORY37694.1 - 4.7e-05 23.2 0.4 0.087 12.5 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 ORY37694.1 - 0.00027 21.0 0.0 0.45 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 ORY37694.1 - 0.00031 21.1 0.0 0.84 10.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase UFD1 PF03152.14 ORY37694.1 - 0.00032 20.2 0.0 0.0014 18.2 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin fusion degradation protein UFD1 AAA_2 PF07724.14 ORY37694.1 - 0.00043 20.4 0.0 0.011 15.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 ORY37694.1 - 0.00052 19.6 2.0 1.4 8.4 0.0 4.6 4 1 1 5 5 4 1 AAA domain TIP49 PF06068.13 ORY37694.1 - 0.00064 19.0 0.1 0.018 14.3 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain NB-ARC PF00931.22 ORY37694.1 - 0.00066 18.9 0.1 1.2 8.2 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_18 PF13238.6 ORY37694.1 - 0.0014 19.1 0.0 0.028 15.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 ORY37694.1 - 0.0049 16.4 0.0 1.5 8.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 ORY37694.1 - 0.0054 16.5 0.3 0.87 9.3 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.6 ORY37694.1 - 0.014 15.9 0.0 0.16 12.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 ORY37694.1 - 0.014 14.8 0.1 2 7.7 0.0 2.4 2 0 0 2 2 2 0 KaiC NTPase_1 PF03266.15 ORY37694.1 - 0.017 15.0 0.4 0.9 9.4 0.0 2.7 3 0 0 3 3 2 0 NTPase Mg_chelatase PF01078.21 ORY37694.1 - 0.024 14.0 0.1 1.5 8.1 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.18 ORY37694.1 - 0.029 14.2 0.0 2.7 7.8 0.0 2.9 3 0 0 3 3 3 0 Bacterial dnaA protein AAA_24 PF13479.6 ORY37694.1 - 0.031 14.0 0.0 6.1 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 ORY37694.1 - 0.047 13.6 0.0 0.58 10.1 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain PEX-2N PF09263.10 ORY37694.1 - 0.092 13.1 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal AAA_3 PF07726.11 ORY37694.1 - 0.11 12.4 0.0 2.9 7.8 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 ORY37694.1 - 0.24 10.5 0.7 3.4 6.7 0.0 2.9 4 0 0 4 4 4 0 Parvovirus non-structural protein NS1 Ank_2 PF12796.7 ORY37695.1 - 3.1e-25 88.6 1.0 4.2e-10 40.1 0.1 4.1 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY37695.1 - 1.8e-16 59.9 7.6 0.0022 18.3 0.1 7.3 1 1 7 8 8 8 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY37695.1 - 3e-14 53.2 4.3 0.0016 19.0 0.0 5.5 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY37695.1 - 4.5e-12 45.0 7.0 2.4 9.0 0.0 8.2 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 ORY37695.1 - 1.2e-09 38.2 7.7 0.073 13.6 0.0 7.6 6 2 2 8 8 8 2 Ankyrin repeat Helicase_PWI PF18149.1 ORY37695.1 - 0.11 12.7 0.2 1.3 9.3 0.0 2.2 2 0 0 2 2 2 0 N-terminal helicase PWI domain Acyltransferase PF01553.21 ORY37696.1 - 3.2e-33 114.2 0.0 5e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase fn3_3 PF14686.6 ORY37697.1 - 0.0005 19.8 0.3 0.99 9.2 0.0 3.6 3 0 0 3 3 3 2 Polysaccharide lyase family 4, domain II I-set PF07679.16 ORY37697.1 - 0.0059 16.6 0.0 59 3.8 0.0 4.9 6 0 0 6 6 6 1 Immunoglobulin I-set domain NAS PF03059.16 ORY37697.1 - 0.091 12.1 0.0 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Nicotianamine synthase protein ENTH PF01417.20 ORY37698.1 - 4.8e-39 133.3 0.0 7e-39 132.7 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 ORY37698.1 - 0.018 14.0 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 ANTH domain Dynactin PF12455.8 ORY37699.1 - 2.6e-44 151.6 2.5 2.6e-44 151.6 2.5 5.9 4 2 1 5 5 5 1 Dynein associated protein CAP_GLY PF01302.25 ORY37699.1 - 1.3e-17 63.6 1.6 2.3e-17 62.7 1.6 1.4 1 0 0 1 1 1 1 CAP-Gly domain Cnn_1N PF07989.11 ORY37699.1 - 0.0027 17.8 3.8 0.0027 17.8 3.8 13.0 9 2 0 10 10 10 2 Centrosomin N-terminal motif 1 MscS_porin PF12795.7 ORY37699.1 - 0.0029 17.2 29.8 0.0029 17.2 29.8 8.4 6 3 2 8 8 8 2 Mechanosensitive ion channel porin domain Soyouz_module PF14313.6 ORY37699.1 - 0.024 14.4 0.1 0.16 11.7 0.1 2.5 2 0 0 2 2 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) DDE_Tnp_1_3 PF13612.6 ORY37699.1 - 0.77 9.8 10.5 1.9 8.4 1.9 4.0 3 0 0 3 3 3 0 Transposase DDE domain Acyltransferase PF01553.21 ORY37700.1 - 9.2e-23 80.3 0.0 1.6e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Trehalose_recp PF06151.13 ORY37700.1 - 0.014 14.0 1.6 0.022 13.4 1.6 1.2 1 0 0 1 1 1 0 Trehalose receptor DDE_Tnp_4 PF13359.6 ORY37759.1 - 1.2e-10 41.3 0.0 1.6e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease FHA PF00498.26 ORY37761.1 - 7.9e-14 51.8 0.1 1.6e-13 50.8 0.1 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 ORY37761.1 - 4.9e-10 39.6 0.1 6.8e-10 39.1 0.1 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase PF00069.25 ORY37762.1 - 1.1e-43 149.5 0.0 2.6e-43 148.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY37762.1 - 2e-22 79.7 0.0 3.3e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY37762.1 - 2.8e-06 26.8 0.0 4.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 ORY37762.1 - 0.036 13.0 0.1 3.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase APH PF01636.23 ORY37762.1 - 0.15 12.0 0.1 4.3 7.2 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-CCCH_2 PF14608.6 ORY37763.1 - 9.2e-06 25.9 9.9 0.00031 21.1 0.6 2.8 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 ORY37763.1 - 1.6e-05 24.7 9.0 4.1e-05 23.5 2.3 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 ORY37763.1 - 3.8e-05 23.5 0.2 3.8e-05 23.5 0.2 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 ORY37763.1 - 0.0011 18.6 7.0 0.0021 17.8 0.6 2.4 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 ORY37763.1 - 0.025 14.8 3.6 0.025 14.8 3.6 2.0 1 1 1 2 2 2 0 Zinc-finger containing family Torus PF16131.5 ORY37763.1 - 0.076 13.7 2.4 0.86 10.3 0.2 2.2 1 1 1 2 2 2 0 Torus domain MIF4G PF02854.19 ORY37765.1 - 7.2e-61 205.5 6.6 1.9e-31 109.3 0.3 3.7 3 1 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 ORY37765.1 - 6.5e-32 111.1 10.8 6.5e-32 111.1 10.8 2.1 2 0 0 2 2 2 1 Up-frameshift suppressor 2 Bap31 PF05529.12 ORY37766.1 - 1.5e-21 76.7 1.6 2.5e-21 75.9 1.6 1.3 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Syja_N PF02383.18 ORY37767.1 - 6.5e-79 265.5 0.0 1.1e-78 264.8 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain Peptidase_M48 PF01435.18 ORY37768.1 - 6.6e-28 97.8 0.1 2.6e-27 95.9 0.0 2.0 2 1 0 2 2 2 1 Peptidase family M48 Nrap_D2 PF17403.2 ORY37768.1 - 0.061 13.1 0.2 0.77 9.5 0.0 2.4 2 0 0 2 2 2 0 Nrap protein PAP/OAS-like domain SATase_N PF06426.14 ORY37768.1 - 0.2 12.1 0.8 4.8 7.6 0.1 2.4 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal RhoGEF PF00621.20 ORY37769.1 - 1.3e-48 165.7 1.1 1.3e-48 165.7 1.1 2.1 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 ORY37769.1 - 0.0027 18.2 0.0 0.011 16.3 0.0 2.0 1 0 0 1 1 1 1 PH domain LRS4 PF10422.9 ORY37769.1 - 8.9 5.8 12.2 20 4.7 12.2 1.6 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Gly_transf_sug PF04488.15 ORY37773.1 - 0.00038 21.0 0.1 0.0008 20.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Mid1 PF12929.7 ORY37773.1 - 0.088 12.0 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Stretch-activated Ca2+-permeable channel component Gly_transf_sug PF04488.15 ORY37774.1 - 7.3e-33 113.1 4.3 2.3e-10 41.0 0.0 4.9 4 1 0 4 4 4 4 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 ORY37774.1 - 0.00036 20.0 2.8 0.58 9.4 0.1 3.4 3 0 0 3 3 3 2 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 ORY37774.1 - 0.034 13.5 0.2 3.7 6.9 0.1 3.5 3 0 0 3 3 3 0 Capsular polysaccharide synthesis protein CBFD_NFYB_HMF PF00808.23 ORY37775.1 - 1.3e-10 41.4 0.1 1.6e-10 41.1 0.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY37775.1 - 6.1e-08 33.1 0.1 8e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 ORY37775.1 - 0.15 12.2 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) F-box-like PF12937.7 ORY37776.1 - 5.9e-06 26.1 1.0 4.1e-05 23.4 0.1 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY37776.1 - 0.00059 19.7 0.0 0.0023 17.8 0.0 2.0 1 0 0 1 1 1 1 F-box domain XPG_I_2 PF12813.7 ORY37779.1 - 1.2e-10 41.3 0.5 4.6e-07 29.6 0.0 2.8 3 0 0 3 3 3 2 XPG domain containing Usp PF00582.26 ORY37779.1 - 0.0015 19.0 0.1 0.0044 17.5 0.1 1.7 1 0 0 1 1 1 1 Universal stress protein family XPG_I PF00867.18 ORY37779.1 - 0.041 14.2 0.0 0.094 13.1 0.0 1.7 1 0 0 1 1 1 0 XPG I-region DUF5615 PF18480.1 ORY37779.1 - 0.17 11.6 0.0 0.41 10.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) NAD_binding_10 PF13460.6 ORY37780.1 - 2.4e-32 112.3 0.0 2.7e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY37780.1 - 1e-06 28.5 0.1 1.3e-06 28.1 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 ORY37780.1 - 0.0037 17.7 0.0 0.0048 17.3 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ORY37780.1 - 0.0043 17.1 0.3 0.011 15.8 0.2 1.7 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 ORY37780.1 - 0.031 13.7 0.1 0.048 13.1 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.19 ORY37780.1 - 0.059 12.4 0.0 0.071 12.1 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 ORY37780.1 - 0.061 12.6 1.5 0.88 8.9 1.6 2.4 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Actin PF00022.19 ORY37781.1 - 5.9e-149 496.1 0.0 1.8e-148 494.5 0.0 1.6 1 1 0 1 1 1 1 Actin GerD PF17898.1 ORY37781.1 - 0.087 12.8 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Spore germination GerD central core domain Proteasome PF00227.26 ORY37782.1 - 1.2e-59 201.0 0.1 1.6e-59 200.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORY37782.1 - 2.7e-13 49.3 0.1 4.4e-13 48.6 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature TRP_N PF14558.6 ORY37782.1 - 0.053 13.9 0.1 0.12 12.8 0.1 1.5 1 0 0 1 1 1 0 ML-like domain MFS_1 PF07690.16 ORY37783.1 - 5.1e-23 81.6 34.4 2.8e-20 72.5 27.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY37783.1 - 0.52 9.1 29.7 0.041 12.7 6.1 3.8 3 1 1 4 4 4 0 Sugar (and other) transporter Actin PF00022.19 ORY37784.1 - 3.6e-134 447.4 0.0 1.2e-133 445.7 0.0 1.7 1 1 0 1 1 1 1 Actin Vg_Tdu PF07545.14 ORY37785.1 - 0.071 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Vestigial/Tondu family Chromo PF00385.24 ORY37788.1 - 9.9e-07 28.6 0.1 9.9e-07 28.6 0.1 2.3 3 0 0 3 3 3 1 Chromo (CHRromatin Organisation MOdifier) domain IHABP4_N PF16174.5 ORY37788.1 - 0.41 11.3 16.5 0.33 11.5 0.8 2.3 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal PDDEXK_9 PF08011.11 ORY37788.1 - 0.42 10.6 3.4 37 4.3 0.0 2.4 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily SRP-alpha_N PF04086.13 ORY37788.1 - 0.75 9.7 14.9 1.9 8.3 5.9 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF3438 PF11920.8 ORY37788.1 - 0.84 8.8 5.6 0.082 12.2 0.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3438) DUF4050 PF13259.6 ORY37788.1 - 2.6 8.3 14.7 2.1 8.6 3.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) DUF4678 PF15727.5 ORY37788.1 - 2.7 7.2 8.9 0.53 9.5 2.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4678) TP53IP5 PF15331.6 ORY37789.1 - 0.87 9.7 11.1 0.98 9.5 11.1 1.0 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 SAPS PF04499.15 ORY37789.1 - 5.8 5.6 12.4 6.5 5.4 12.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein LRR_4 PF12799.7 ORY37790.1 - 5.9e-12 45.6 15.8 9.7e-05 22.7 1.7 5.0 1 1 6 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY37790.1 - 5e-08 32.6 18.5 2.1e-05 24.2 3.4 4.6 2 2 3 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 ORY37790.1 - 0.0038 17.6 10.1 20 6.3 0.3 6.2 6 1 0 6 6 6 1 Leucine Rich Repeat Ribul_P_3_epim PF00834.19 ORY37790.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family LRR_6 PF13516.6 ORY37790.1 - 0.96 9.7 18.0 0.73 10.0 0.3 5.2 6 0 0 6 6 6 0 Leucine Rich repeat LRR_4 PF12799.7 ORY37791.1 - 2.7e-08 34.0 1.4 2.9e-05 24.3 0.6 2.9 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY37791.1 - 4.6e-05 23.1 1.8 0.0015 18.3 0.6 2.4 2 1 1 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 ORY37791.1 - 0.018 15.1 4.8 4.9 7.5 0.1 4.6 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 ORY37791.1 - 0.27 11.9 3.0 63 4.7 0.0 4.2 4 1 1 5 5 5 0 Leucine Rich Repeat Gly_acyl_tr_C PF08444.10 ORY37792.1 - 0.065 13.5 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region FR47 PF08445.10 ORY37792.1 - 0.17 11.8 0.0 22 5.1 0.0 2.4 2 0 0 2 2 2 0 FR47-like protein TPR_2 PF07719.17 ORY37794.1 - 1.9e-23 80.6 19.1 2.3e-05 24.1 0.3 8.8 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 ORY37794.1 - 3e-21 75.5 10.1 7.7e-07 29.3 0.4 6.3 4 2 1 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 ORY37794.1 - 9.8e-21 72.7 21.2 0.00042 20.0 0.8 8.0 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 ORY37794.1 - 2.9e-20 70.7 12.9 0.00055 19.9 0.8 8.4 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 ORY37794.1 - 4.6e-18 63.8 4.5 0.00088 19.1 0.0 8.1 7 2 1 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY37794.1 - 3.6e-11 42.5 7.0 0.013 15.1 0.7 5.9 5 1 1 6 6 6 2 TPR repeat TPR_16 PF13432.6 ORY37794.1 - 1.4e-09 38.4 8.2 0.00025 21.6 0.1 6.0 4 1 1 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY37794.1 - 4.4e-08 33.2 7.3 0.01 16.0 0.3 4.7 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 ORY37794.1 - 7e-07 28.9 2.6 0.018 14.4 1.3 3.8 3 1 1 4 4 4 2 MalT-like TPR region TPR_19 PF14559.6 ORY37794.1 - 8.8e-07 29.3 15.9 0.01 16.3 0.8 6.3 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY37794.1 - 1.5e-06 28.5 10.7 3.3 8.8 0.1 7.1 7 2 1 8 8 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY37794.1 - 7.5e-06 26.3 14.8 13 6.6 0.6 7.6 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORY37794.1 - 0.0006 20.0 3.5 62 4.3 0.2 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_21 PF09976.9 ORY37794.1 - 0.0012 18.5 10.9 0.017 14.8 0.2 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 ORY37794.1 - 0.0014 18.5 2.0 65 3.6 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_3 PF07720.12 ORY37794.1 - 0.033 14.2 8.7 11 6.1 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat USP8_dimer PF08969.11 ORY37794.1 - 0.12 12.6 0.2 3.2 8.0 0.0 2.7 2 1 0 2 2 2 0 USP8 dimerisation domain Mif2_N PF15624.6 ORY37794.1 - 0.15 12.7 5.5 1.9 9.2 2.4 2.5 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal MIT PF04212.18 ORY37794.1 - 0.17 12.0 4.4 12 6.0 0.2 3.6 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_9 PF13371.6 ORY37794.1 - 0.18 11.9 3.1 15 5.8 0.0 4.9 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 ORY37794.1 - 0.95 10.3 5.6 80 4.3 0.0 5.0 6 0 0 6 6 4 0 Tetratricopeptide repeat CK_II_beta PF01214.18 ORY37795.1 - 3.6e-67 225.7 0.0 5e-67 225.2 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit PGA2 PF07543.12 ORY37795.1 - 0.31 11.0 2.5 0.48 10.4 2.5 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 BUD22 PF09073.10 ORY37795.1 - 2.4 7.4 10.7 3.6 6.8 10.7 1.1 1 0 0 1 1 1 0 BUD22 PPP4R2 PF09184.11 ORY37795.1 - 2.9 7.4 9.3 4.3 6.8 9.3 1.2 1 0 0 1 1 1 0 PPP4R2 Pox_Ag35 PF03286.14 ORY37795.1 - 5.5 6.7 7.5 11 5.8 7.5 1.4 1 1 0 1 1 1 0 Pox virus Ag35 surface protein Cwf_Cwc_15 PF04889.12 ORY37795.1 - 8.5 6.0 10.7 12 5.5 10.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein LRR_4 PF12799.7 ORY37796.1 - 8.9e-10 38.7 8.8 0.0012 19.2 0.1 4.7 2 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY37796.1 - 8.1e-06 25.5 8.1 0.013 15.3 0.1 3.4 2 1 2 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 ORY37796.1 - 0.0005 20.2 10.2 0.1 13.2 0.1 5.3 5 0 0 5 5 5 1 Leucine Rich Repeat Xol-1_GHMP-like PF09109.10 ORY37796.1 - 0.043 13.7 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Switch protein XOL-1, GHMP-like DUF2013 PF09431.10 ORY37797.1 - 0.096 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2013) APC1_C PF18122.1 ORY37798.1 - 0.087 12.8 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain Pox_I1 PF03289.13 ORY37799.1 - 0.05 12.7 0.1 0.071 12.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus protein I1 MFS_5 PF05631.14 ORY37800.1 - 3.5e-99 332.1 14.5 3.2e-98 328.9 14.5 2.0 1 1 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 ORY37800.1 - 2.1e-18 66.4 52.5 1.4e-17 63.7 31.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY37800.1 - 8.3e-09 34.8 17.7 1.1e-08 34.5 2.5 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter LRR_4 PF12799.7 ORY37802.1 - 3.1e-11 43.3 21.9 0.0064 16.9 0.8 5.1 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY37802.1 - 1.1e-10 41.2 19.3 7.9e-06 25.6 1.8 5.0 3 1 2 5 5 5 4 Leucine rich repeat CAP_GLY PF01302.25 ORY37802.1 - 4.6e-09 36.2 0.0 8.7e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_9 PF14580.6 ORY37802.1 - 1.4e-05 24.6 3.9 0.015 14.8 0.4 3.2 2 1 2 4 4 4 3 Leucine-rich repeat DUF2840 PF11000.8 ORY37802.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2840) LRR_6 PF13516.6 ORY37802.1 - 0.46 10.7 11.7 20 5.6 0.0 5.4 5 0 0 5 5 5 0 Leucine Rich repeat Sdh5 PF03937.16 ORY37803.1 - 2.7e-21 75.3 0.7 4.1e-21 74.7 0.7 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Y_phosphatase PF00102.27 ORY37804.1 - 2.4e-12 46.9 0.0 6e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 ORY37804.1 - 3e-11 43.3 0.0 7.5e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 ORY37804.1 - 0.00038 20.2 0.1 0.00096 18.9 0.0 1.7 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) RhoGAP PF00620.27 ORY37804.1 - 0.03 14.1 0.1 0.095 12.5 0.0 1.8 2 0 0 2 2 2 0 RhoGAP domain Y_phosphatase3 PF13350.6 ORY37804.1 - 0.058 13.4 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family His_Phos_1 PF00300.22 ORY37804.1 - 0.068 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) TOM13 PF08219.11 ORY37805.1 - 0.1 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Outer membrane protein TOM13 FYVE_2 PF02318.16 ORY37805.1 - 0.24 11.6 8.0 1.3 9.2 0.6 2.7 2 0 0 2 2 2 0 FYVE-type zinc finger Siva PF05458.12 ORY37805.1 - 0.28 10.8 11.6 0.68 9.6 1.1 2.4 2 0 0 2 2 2 0 Cd27 binding protein (Siva) ARL2_Bind_BART PF11527.8 ORY37806.1 - 2.7e-27 95.2 6.0 3.8e-27 94.7 6.0 1.2 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART DUF3785 PF12653.7 ORY37806.1 - 0.032 14.3 1.1 0.13 12.4 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3785) Ndr PF03096.14 ORY37806.1 - 0.11 11.2 0.1 0.13 10.9 0.1 1.1 1 0 0 1 1 1 0 Ndr family RINGv PF12906.7 ORY37807.1 - 7.2e-13 48.4 7.6 3e-12 46.5 7.6 2.0 1 1 0 1 1 1 1 RING-variant domain RNA_POL_M_15KD PF02150.16 ORY37807.1 - 0.024 14.5 0.3 0.082 12.8 0.3 1.9 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit Sigma_reg_N PF13800.6 ORY37807.1 - 1 9.7 2.5 2.1 8.7 2.5 1.4 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Ras PF00071.22 ORY37808.1 - 5.4e-46 156.2 0.0 6.3e-46 155.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY37808.1 - 6.2e-28 97.4 0.0 1.3e-27 96.4 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY37808.1 - 1.6e-09 37.4 0.1 3e-09 36.6 0.0 1.4 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY37808.1 - 0.001 19.1 0.0 0.0018 18.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 ORY37808.1 - 0.0044 16.2 0.2 0.38 9.9 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 ORY37808.1 - 0.036 13.4 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Pox_A32 PF04665.12 ORY37808.1 - 0.049 13.1 0.1 0.085 12.3 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_24 PF13479.6 ORY37808.1 - 0.097 12.4 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY37808.1 - 0.11 12.9 0.0 0.18 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 ORY37808.1 - 0.12 12.3 0.1 12 5.7 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 ORY37808.1 - 0.17 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region M20_dimer PF07687.14 ORY37809.1 - 3.9e-08 33.2 0.0 8.5e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain Dicty_CAR PF05462.11 ORY37811.1 - 7.4e-07 28.6 14.9 5.9e-06 25.6 14.9 2.1 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 ORY37811.1 - 0.01 15.2 10.5 0.02 14.2 10.4 1.6 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 ORY37811.1 - 0.014 14.7 14.2 0.019 14.3 14.2 1.4 1 1 0 1 1 1 0 7 transmembrane receptor (Secretin family) 7TM_GPCR_Srsx PF10320.9 ORY37811.1 - 0.19 11.1 10.9 0.018 14.4 4.5 2.2 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx GST_C_6 PF17171.4 ORY37812.1 - 1.9e-11 43.6 0.0 4.2e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 ORY37812.1 - 1.4e-07 31.8 0.4 2.7e-07 30.9 0.4 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 ORY37812.1 - 0.00023 21.8 0.1 0.00074 20.2 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 ORY37812.1 - 0.00048 20.1 0.0 0.0025 17.8 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain BCAS2 PF05700.11 ORY37812.1 - 0.0019 18.0 2.4 0.0037 17.0 2.4 1.5 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF4407 PF14362.6 ORY37812.1 - 0.4 10.0 4.7 0.75 9.1 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Robl_LC7 PF03259.17 ORY37813.1 - 3.9e-06 26.6 0.1 0.00019 21.2 0.1 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain FA_desaturase PF00487.24 ORY37815.1 - 0.068 13.0 0.1 0.081 12.7 0.1 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Autophagy_N PF03986.13 ORY37818.1 - 2.9e-44 150.4 0.1 6.2e-44 149.3 0.1 1.7 1 1 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 ORY37818.1 - 2.1e-19 69.9 0.7 4.5e-19 68.8 0.7 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 ORY37818.1 - 3.8e-15 55.1 1.6 8.8e-15 53.9 1.6 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal PH PF00169.29 ORY37819.1 - 0.039 14.5 0.0 0.14 12.7 0.0 2.1 1 0 0 1 1 1 0 PH domain CH PF00307.31 ORY37820.1 - 7.1e-23 80.9 0.1 1.1e-22 80.3 0.1 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 ORY37820.1 - 0.0012 19.1 0.2 0.0018 18.5 0.2 1.3 1 0 0 1 1 1 1 CDC24 Calponin Calponin PF00402.18 ORY37820.1 - 0.077 12.7 1.0 0.15 11.8 0.1 2.0 3 0 0 3 3 3 0 Calponin family repeat CdiI_2 PF18593.1 ORY37820.1 - 0.11 13.2 0.3 0.38 11.4 0.0 1.9 2 0 0 2 2 2 0 CdiI immunity protein CAMSAP_CH PF11971.8 ORY37820.1 - 0.13 12.1 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain PEX11 PF05648.14 ORY37821.1 - 9.6e-27 93.9 0.3 1.1e-26 93.7 0.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) F-box-like PF12937.7 ORY37822.1 - 0.034 14.0 0.4 0.19 11.6 0.2 2.4 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.7 ORY37823.1 - 0.0054 16.6 1.7 0.0074 16.2 0.2 2.2 2 0 0 2 2 2 1 F-box-like HPD PF05044.12 ORY37823.1 - 0.0081 16.0 0.1 0.021 14.7 0.1 1.6 1 0 0 1 1 1 1 Homeo-prospero domain F-box PF00646.33 ORY37823.1 - 0.017 15.0 0.1 0.07 13.0 0.0 2.1 2 0 0 2 2 2 0 F-box domain Fels1 PF05666.11 ORY37823.1 - 0.12 12.0 0.3 0.26 10.9 0.3 1.5 1 0 0 1 1 1 0 Fels-1 Prophage Protein-like Neurochondrin PF05536.11 ORY37825.1 - 4.2e-12 45.2 0.0 3.6e-11 42.1 0.0 2.2 2 0 0 2 2 2 1 Neurochondrin Complex1_LYR PF05347.15 ORY37826.1 - 8.1e-16 57.8 0.5 1.1e-15 57.5 0.5 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 ORY37826.1 - 0.00064 20.3 0.4 0.00088 19.8 0.3 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 ORY37826.1 - 0.014 16.1 0.2 0.016 15.9 0.2 1.2 1 0 0 1 1 1 0 Complex1_LYR-like Jag_N PF14804.6 ORY37826.1 - 0.053 13.9 0.2 0.11 12.9 0.2 1.6 1 1 0 1 1 1 0 Jag N-terminus Viral_RdRp_C PF17501.2 ORY37827.1 - 0.026 15.0 0.1 0.041 14.3 0.1 1.3 1 0 0 1 1 1 0 Viral RNA-directed RNA polymerase RRM_1 PF00076.22 ORY37828.1 - 4.8e-20 71.1 0.0 5.1e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY37828.1 - 0.0065 16.3 0.0 0.013 15.3 0.0 1.5 1 1 0 1 1 1 1 Occluded RNA-recognition motif Methyltransf_5 PF01795.19 ORY37886.1 - 1.5e-78 264.4 0.0 6.5e-35 121.1 0.0 3.1 3 0 0 3 3 3 3 MraW methylase family Methyltransf_25 PF13649.6 ORY37886.1 - 0.012 16.3 0.0 0.038 14.7 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 ORY37886.1 - 0.035 14.2 0.0 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 ORY37886.1 - 0.045 14.5 0.0 0.49 11.2 0.0 2.6 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_31 PF13847.6 ORY37886.1 - 0.15 11.8 0.1 0.69 9.7 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain DUF1616 PF07760.11 ORY37887.1 - 0.0016 17.9 0.0 0.0042 16.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1616) DUF3446 PF11928.8 ORY37887.1 - 0.037 14.3 2.3 0.037 14.3 2.3 1.6 2 0 0 2 2 2 0 Early growth response N-terminal domain SR-25 PF10500.9 ORY37887.1 - 2.4 7.7 11.2 3.2 7.3 11.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WD40 PF00400.32 ORY37888.1 - 6.2e-44 147.1 17.2 1.2e-08 35.5 0.3 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY37888.1 - 2.3e-28 98.3 4.5 9.8e-08 32.2 0.3 5.5 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 ORY37888.1 - 2.9e-09 36.5 0.2 6e-09 35.6 0.2 1.6 1 0 0 1 1 1 1 LisH eIF2A PF08662.11 ORY37888.1 - 6.4e-07 29.4 1.4 0.011 15.7 0.0 3.5 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 ORY37888.1 - 0.00014 20.1 1.2 0.00031 18.9 0.1 1.9 1 1 1 2 2 2 1 IKI3 family Nfu_N PF08712.11 ORY37890.1 - 1.1e-30 105.6 0.0 4.6e-30 103.5 0.0 1.9 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 ORY37890.1 - 6.7e-27 93.4 0.1 1.4e-26 92.4 0.1 1.5 1 0 0 1 1 1 1 NifU-like domain IMD PF08397.11 ORY37890.1 - 0.036 13.4 0.1 0.049 13.0 0.1 1.1 1 0 0 1 1 1 0 IRSp53/MIM homology domain Alk_phosphatase PF00245.20 ORY37891.1 - 1.1e-46 159.6 0.2 1.5e-46 159.2 0.2 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 ORY37891.1 - 0.0051 16.2 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily SBDS_C PF09377.10 ORY37892.1 - 2.2e-38 130.8 1.0 4.5e-38 129.8 1.0 1.5 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 ORY37892.1 - 5.8e-34 116.0 0.9 1.4e-33 114.8 0.9 1.7 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein B2-adapt-app_C PF09066.10 ORY37892.1 - 0.019 15.1 1.3 3.9 7.6 0.2 2.3 2 0 0 2 2 2 0 Beta2-adaptin appendage, C-terminal sub-domain LRR_9 PF14580.6 ORY37893.1 - 7e-17 61.5 6.1 1.2e-16 60.7 6.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 ORY37893.1 - 9.7e-10 38.6 30.9 2.6e-06 27.7 8.8 3.7 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY37893.1 - 9.9e-07 28.4 22.6 1.2e-05 24.9 8.6 2.9 1 1 3 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 ORY37893.1 - 0.0017 18.2 3.1 6.1 7.2 0.1 3.7 3 0 0 3 3 3 2 Leucine Rich repeat Presenilin PF01080.17 ORY37893.1 - 0.27 9.9 0.5 0.48 9.1 0.5 1.3 1 0 0 1 1 1 0 Presenilin FAM184 PF15665.5 ORY37894.1 - 1.3e-07 31.6 1.0 1.8e-07 31.2 1.0 1.2 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B CDP-OH_P_transf PF01066.21 ORY37895.1 - 7e-16 58.8 0.4 7e-16 58.8 0.4 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Arteri_Gl PF00951.18 ORY37895.1 - 0.61 9.9 3.3 2.8 7.7 0.5 2.3 1 1 1 2 2 2 0 Arterivirus GL envelope glycoprotein WD40 PF00400.32 ORY37896.1 - 1e-12 48.3 5.1 0.023 15.5 0.1 5.9 5 0 0 5 5 5 4 WD domain, G-beta repeat SRA1 PF07304.11 ORY37896.1 - 1.3e-07 31.5 0.1 1.3e-07 31.5 0.1 4.9 6 1 0 6 6 6 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.15 ORY37896.1 - 2.3e-07 31.0 0.1 5.5e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 Prp18 domain ANAPC4_WD40 PF12894.7 ORY37896.1 - 3.2e-05 24.1 0.0 2.5 8.4 0.0 4.3 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain RRS1 PF04939.12 ORY37897.1 - 3.6e-42 144.0 4.4 3.6e-42 144.0 4.4 1.6 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) bZIP_2 PF07716.15 ORY37898.1 - 2.9e-10 40.0 7.5 5.8e-10 39.1 7.5 1.5 1 0 0 1 1 1 1 Basic region leucine zipper Serglycin PF04360.12 ORY37898.1 - 0.027 14.4 2.8 0.064 13.2 2.8 1.6 1 0 0 1 1 1 0 Serglycin bZIP_1 PF00170.21 ORY37898.1 - 0.066 13.3 7.3 0.13 12.3 7.3 1.4 1 0 0 1 1 1 0 bZIP transcription factor Brix PF04427.18 ORY37899.1 - 4.6e-32 111.7 0.1 6.4e-32 111.2 0.1 1.2 1 0 0 1 1 1 1 Brix domain RE_HindVP PF09519.10 ORY37899.1 - 0.14 11.1 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 HindVP restriction endonuclease MRP-S34 PF16053.5 ORY37900.1 - 3.2e-08 33.3 0.0 5e-08 32.7 0.0 1.3 2 0 0 2 2 2 1 Mitochondrial 28S ribosomal protein S34 ATP12 PF07542.11 ORY37901.1 - 2.1e-34 118.4 0.0 3.4e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein Pacs-1 PF10254.9 ORY37902.1 - 0.011 14.7 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein ADAM17_MPD PF16698.5 ORY37903.1 - 0.13 12.6 0.5 0.24 11.8 0.5 1.4 1 0 0 1 1 1 0 Membrane-proximal domain, switch, for ADAM17 NIF PF03031.18 ORY37906.1 - 0.018 14.8 0.1 0.23 11.2 0.1 2.5 1 1 0 1 1 1 0 NLI interacting factor-like phosphatase Sec6 PF06046.13 ORY37909.1 - 1e-122 410.4 5.0 1.2e-122 410.2 5.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec6 Peptidase_M24_C PF16188.5 ORY37909.1 - 0.034 14.2 0.5 0.38 10.8 0.1 2.9 3 0 0 3 3 3 0 C-terminal region of peptidase_M24 Med30 PF11315.8 ORY37909.1 - 0.14 12.4 1.6 0.27 11.4 0.2 2.2 2 0 0 2 2 2 0 Mediator complex subunit 30 Guanylate_cyc PF00211.20 ORY37909.1 - 0.15 11.6 0.0 0.47 10.1 0.0 1.8 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain zf-CCCH PF00642.24 ORY37911.1 - 2.8e-10 39.8 19.5 1.4e-06 28.0 3.0 3.0 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 ORY37911.1 - 4.1e-05 23.3 0.0 7.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 ORY37911.1 - 0.029 14.4 2.6 0.029 14.4 2.6 3.7 4 0 0 4 4 4 0 Zinc finger domain zf-CCCH_3 PF15663.5 ORY37911.1 - 0.037 14.2 6.8 0.54 10.5 1.0 2.3 2 0 0 2 2 2 0 Zinc-finger containing family Torus PF16131.5 ORY37911.1 - 0.062 14.0 7.9 0.17 12.6 0.1 2.7 2 1 1 3 3 3 0 Torus domain tRNA-synt_1 PF00133.22 ORY37912.1 - 7e-215 714.8 0.1 1.7e-213 710.3 0.1 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 ORY37912.1 - 4.4e-36 124.1 0.1 1.3e-35 122.6 0.1 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 ORY37912.1 - 2.8e-15 56.0 0.4 1.4e-06 27.3 0.0 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 ORY37912.1 - 1.4e-13 50.8 4.0 1.1e-11 44.5 0.1 2.8 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 ORY37912.1 - 0.0042 16.5 0.1 0.18 11.1 0.0 3.1 4 0 0 4 4 4 1 tRNA synthetases class I (C) catalytic domain Val_tRNA-synt_C PF10458.9 ORY37912.1 - 0.0096 16.2 4.5 0.024 14.9 4.5 1.7 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm DUF724 PF05266.14 ORY37912.1 - 0.2 11.4 2.6 0.42 10.4 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Fibrillarin PF01269.17 ORY37913.1 - 1.2e-108 361.5 0.0 1.4e-108 361.2 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 ORY37913.1 - 3e-06 27.1 0.0 4.1e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 ORY37913.1 - 0.011 15.5 0.1 0.019 14.7 0.1 1.4 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 ORY37913.1 - 0.017 15.2 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 ORY37913.1 - 0.018 14.7 0.0 0.04 13.5 0.0 1.6 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DREV PF05219.12 ORY37913.1 - 0.089 11.9 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase FoP_duplication PF13865.6 ORY37913.1 - 1.6 9.3 12.3 2.9 8.5 12.3 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 RNA12 PF10443.9 ORY37914.1 - 2.9e-83 280.1 0.2 1.2e-47 162.7 0.0 3.1 2 1 1 3 3 3 3 RNA12 protein RRM_1 PF00076.22 ORY37914.1 - 1.3e-09 37.8 0.0 3.4e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 ORY37916.1 - 1.9e-12 47.1 0.1 2e-12 47.1 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY37916.1 - 0.0019 17.5 0.1 0.0021 17.4 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Peroxin-22 PF12827.7 ORY37916.1 - 0.056 13.4 0.1 0.12 12.3 0.0 1.5 1 1 1 2 2 2 0 Peroxisomal biogenesis protein family Cyclin_N PF00134.23 ORY37917.1 - 1.4e-09 37.8 0.2 7.5e-09 35.4 0.1 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 ORY37917.1 - 0.06 13.4 0.5 11 6.1 0.1 2.6 2 1 0 2 2 2 0 Transcription factor TFIIB repeat zf-TFIIIC PF12660.7 ORY37918.1 - 1.2e-15 57.3 0.0 2.3e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Bmt2 PF11968.8 ORY37918.1 - 0.18 11.6 0.1 0.31 10.9 0.1 1.2 1 0 0 1 1 1 0 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 DUF2306 PF10067.9 ORY37919.1 - 0.013 15.7 8.9 0.013 15.7 8.9 2.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2306) Herpes_US9 PF06072.11 ORY37919.1 - 0.25 11.3 2.8 0.37 10.7 0.3 2.5 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Fez1 PF06818.15 ORY37920.1 - 0.00026 21.5 27.4 0.015 15.7 27.9 2.2 1 1 1 2 2 2 1 Fez1 DUF5082 PF16888.5 ORY37920.1 - 0.00031 21.0 23.1 0.012 15.8 3.7 3.2 2 1 0 2 2 2 1 Domain of unknown function (DUF5082) SlyX PF04102.12 ORY37920.1 - 0.00034 21.2 4.2 0.00034 21.2 4.2 3.3 2 1 1 3 3 3 1 SlyX APG6_N PF17675.1 ORY37920.1 - 0.0012 19.4 36.5 0.08 13.5 17.5 2.4 1 1 1 2 2 2 2 Apg6 coiled-coil region ADIP PF11559.8 ORY37920.1 - 0.0014 18.8 28.8 0.11 12.6 9.8 3.1 1 1 2 3 3 3 2 Afadin- and alpha -actinin-Binding DUF4472 PF14739.6 ORY37920.1 - 0.0019 18.9 23.7 0.0098 16.6 9.9 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4472) DUF4407 PF14362.6 ORY37920.1 - 0.0021 17.5 21.4 0.018 14.4 21.6 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) DUF1664 PF07889.12 ORY37920.1 - 0.0022 18.1 16.8 0.024 14.6 6.3 2.9 3 0 0 3 3 2 2 Protein of unknown function (DUF1664) Spc7 PF08317.11 ORY37920.1 - 0.0022 17.0 34.5 0.13 11.2 18.9 2.4 1 1 1 2 2 2 2 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 ORY37920.1 - 0.0024 17.8 4.8 0.0024 17.8 4.8 3.5 2 1 1 3 3 3 1 TATA element modulatory factor 1 DNA binding BST2 PF16716.5 ORY37920.1 - 0.0028 18.2 3.8 0.0028 18.2 3.8 3.5 1 1 1 3 3 2 1 Bone marrow stromal antigen 2 FAM76 PF16046.5 ORY37920.1 - 0.0033 16.8 11.4 0.0033 16.8 11.4 2.8 2 1 1 3 3 3 1 FAM76 protein Prefoldin_2 PF01920.20 ORY37920.1 - 0.0039 17.1 4.0 0.0039 17.1 4.0 3.8 2 2 1 3 3 3 1 Prefoldin subunit Sec2p PF06428.11 ORY37920.1 - 0.011 15.7 4.7 0.011 15.7 4.7 3.6 2 2 1 3 3 3 0 GDP/GTP exchange factor Sec2p ZapB PF06005.12 ORY37920.1 - 0.011 16.1 32.3 0.056 13.9 17.4 3.2 2 2 1 3 3 3 0 Cell division protein ZapB DivIC PF04977.15 ORY37920.1 - 0.012 15.4 1.7 0.012 15.4 1.7 4.7 2 2 2 4 4 4 0 Septum formation initiator V_ATPase_I PF01496.19 ORY37920.1 - 0.013 13.5 18.8 0.019 13.0 6.4 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Jnk-SapK_ap_N PF09744.9 ORY37920.1 - 0.015 15.5 6.5 0.015 15.5 6.5 2.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 NPV_P10 PF05531.12 ORY37920.1 - 0.015 15.8 15.5 0.039 14.4 1.5 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein TolA_bind_tri PF16331.5 ORY37920.1 - 0.015 15.3 15.6 0.071 13.2 2.3 4.2 2 1 2 4 4 4 0 TolA binding protein trimerisation Snapin_Pallidin PF14712.6 ORY37920.1 - 0.016 15.6 10.0 0.016 15.6 10.0 2.3 2 1 0 2 2 2 0 Snapin/Pallidin KASH_CCD PF14662.6 ORY37920.1 - 0.017 14.9 31.5 0.019 14.8 17.4 2.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF2968 PF11180.8 ORY37920.1 - 0.019 14.6 22.2 0.12 12.0 4.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) ATG16 PF08614.11 ORY37920.1 - 0.022 15.0 31.5 0.095 12.9 15.2 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF724 PF05266.14 ORY37920.1 - 0.023 14.5 21.7 0.16 11.8 10.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) MAD PF05557.13 ORY37920.1 - 0.027 12.8 27.9 0.35 9.2 28.0 1.9 1 1 0 1 1 1 0 Mitotic checkpoint protein AAA_13 PF13166.6 ORY37920.1 - 0.031 12.9 24.2 0.0066 15.2 17.1 2.0 1 1 1 2 2 2 0 AAA domain GAS PF13851.6 ORY37920.1 - 0.033 13.5 33.4 0.017 14.4 18.8 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TSC22 PF01166.18 ORY37920.1 - 0.037 14.3 1.0 0.037 14.3 1.0 3.3 2 1 1 3 3 1 0 TSC-22/dip/bun family Atg14 PF10186.9 ORY37920.1 - 0.054 12.6 24.5 0.087 11.9 11.7 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 ORY37920.1 - 0.066 13.3 33.2 3 7.9 6.2 4.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF3450 PF11932.8 ORY37920.1 - 0.069 12.4 26.1 0.22 10.8 11.8 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) TMF_TATA_bd PF12325.8 ORY37920.1 - 0.07 13.4 26.7 0.14 12.4 13.1 2.9 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding CALCOCO1 PF07888.11 ORY37920.1 - 0.14 10.9 27.7 0.82 8.5 27.0 1.9 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF812 PF05667.11 ORY37920.1 - 0.2 10.5 24.6 0.17 10.7 6.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) PI3K_P85_iSH2 PF16454.5 ORY37920.1 - 0.27 10.8 24.8 1.4 8.5 8.2 2.6 1 1 2 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Seryl_tRNA_N PF02403.22 ORY37920.1 - 0.4 10.9 31.9 5.7 7.2 9.6 3.3 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Tropomyosin_1 PF12718.7 ORY37920.1 - 0.4 10.8 32.4 0.98 9.6 4.4 2.6 2 1 0 2 2 2 0 Tropomyosin like PspA_IM30 PF04012.12 ORY37920.1 - 0.55 9.8 27.1 0.14 11.7 16.8 2.9 1 1 1 2 2 2 0 PspA/IM30 family DUF2203 PF09969.9 ORY37920.1 - 0.56 10.9 15.9 0.32 11.7 1.2 3.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) HOOK PF05622.12 ORY37920.1 - 0.61 8.2 30.0 1.6 6.8 17.7 2.1 1 1 1 2 2 2 0 HOOK protein JIP_LZII PF16471.5 ORY37920.1 - 0.65 10.2 30.1 1.7 8.8 6.0 5.4 3 2 2 5 5 4 0 JNK-interacting protein leucine zipper II ERM PF00769.19 ORY37920.1 - 0.66 9.8 28.7 1.3 8.8 17.1 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family FlxA PF14282.6 ORY37920.1 - 0.93 9.5 21.1 0.25 11.3 7.1 3.1 1 1 1 3 3 3 0 FlxA-like protein CLZ PF16526.5 ORY37920.1 - 0.93 9.9 26.6 0.95 9.9 1.0 4.7 2 2 3 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CENP-F_leu_zip PF10473.9 ORY37920.1 - 0.94 9.5 33.6 2.8 7.9 17.3 3.0 1 1 1 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 ORY37920.1 - 0.95 9.9 20.8 0.099 13.0 2.7 4.2 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) Noelin-1 PF12308.8 ORY37920.1 - 0.98 9.4 10.7 0.052 13.5 1.3 3.0 2 1 1 3 3 2 0 Neurogenesis glycoprotein COG2 PF06148.11 ORY37920.1 - 1 9.5 14.6 0.069 13.2 6.8 2.4 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 HAUS5 PF14817.6 ORY37920.1 - 1 8.0 18.4 1.9 7.2 17.5 1.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 COG6 PF06419.11 ORY37920.1 - 1.2 7.3 16.8 0.19 9.9 6.5 2.1 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 Syntaxin-6_N PF09177.11 ORY37920.1 - 1.4 9.5 19.8 6 7.5 8.2 3.8 2 2 0 2 2 2 0 Syntaxin 6, N-terminal HemX PF04375.14 ORY37920.1 - 1.5 8.1 21.7 0.18 11.1 10.4 2.7 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase OmpH PF03938.14 ORY37920.1 - 1.5 9.2 28.6 0.67 10.3 17.0 2.7 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) YabA PF06156.13 ORY37920.1 - 1.5 9.5 21.7 1.5 9.5 10.1 3.2 1 1 0 2 2 2 0 Initiation control protein YabA HrpB7 PF09486.10 ORY37920.1 - 1.6 9.1 18.5 1 9.7 0.5 3.5 1 1 3 4 4 4 0 Bacterial type III secretion protein (HrpB7) DUF3584 PF12128.8 ORY37920.1 - 1.6 6.1 28.2 0.84 7.1 9.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) HMMR_N PF15905.5 ORY37920.1 - 1.8 8.0 32.5 9.4 5.6 32.5 2.1 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Sec34 PF04136.15 ORY37920.1 - 2.1 8.2 17.0 0.88 9.4 5.2 2.8 2 2 0 2 2 2 0 Sec34-like family Mod_r PF07200.13 ORY37920.1 - 2.3 8.3 26.7 0.12 12.5 11.8 2.4 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF2730 PF10805.8 ORY37920.1 - 2.7 8.1 14.0 0.095 12.8 4.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) CEP63 PF17045.5 ORY37920.1 - 2.7 7.8 25.1 24 4.7 25.4 2.0 1 1 1 2 2 2 0 Centrosomal protein of 63 kDa IL4 PF00727.18 ORY37920.1 - 3 8.1 10.7 0.25 11.6 0.8 3.2 3 1 0 3 3 3 0 Interleukin 4 DUF1640 PF07798.11 ORY37920.1 - 3.1 7.8 22.4 1.6 8.8 4.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Phage_GP20 PF06810.11 ORY37920.1 - 3.2 7.5 29.8 0.2 11.4 13.4 2.7 1 1 0 2 2 2 0 Phage minor structural protein GP20 DUF4988 PF16378.5 ORY37920.1 - 3.2 7.4 7.7 0.51 10.0 1.4 2.6 2 1 0 2 2 2 0 Domain of unknown function LOH1CR12 PF10158.9 ORY37920.1 - 3.5 7.7 8.0 5.9 6.9 3.1 2.4 2 0 0 2 2 2 0 Tumour suppressor protein DUF4795 PF16043.5 ORY37920.1 - 3.9 7.0 29.1 6.3e+02 -0.2 29.2 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Allexi_40kDa PF05549.11 ORY37920.1 - 4.4 6.7 15.3 1.2 8.6 3.9 2.8 1 1 2 3 3 3 0 Allexivirus 40kDa protein LPP PF04728.13 ORY37920.1 - 4.8 7.7 14.8 1.1 9.6 1.1 4.0 2 2 1 3 3 3 0 Lipoprotein leucine-zipper Laminin_II PF06009.12 ORY37920.1 - 5.1 7.1 23.5 0.066 13.2 8.8 2.8 3 1 0 3 3 2 0 Laminin Domain II YlqD PF11068.8 ORY37920.1 - 5.5 7.4 22.3 1.5 9.2 11.5 2.5 1 1 1 2 2 2 0 YlqD protein DUF4349 PF14257.6 ORY37920.1 - 5.5 6.4 11.8 3 7.2 8.0 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) Macoilin PF09726.9 ORY37920.1 - 5.9 5.3 22.5 8 4.9 22.5 1.1 1 0 0 1 1 1 0 Macoilin family SHE3 PF17078.5 ORY37920.1 - 6.1 6.5 26.6 43 3.7 16.1 2.5 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 TMPIT PF07851.13 ORY37920.1 - 7.3 5.7 18.7 0.56 9.4 7.8 2.1 2 0 0 2 2 2 0 TMPIT-like protein Cob_adeno_trans PF01923.18 ORY37920.1 - 7.6 6.7 7.5 55 3.9 7.5 2.4 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Spc24 PF08286.11 ORY37920.1 - 7.7 6.8 29.6 14 6.0 4.8 4.3 1 1 2 3 3 2 0 Spc24 subunit of Ndc80 WXG100 PF06013.12 ORY37920.1 - 7.8 6.8 11.5 4.1 7.7 0.2 4.1 2 1 1 4 4 4 0 Proteins of 100 residues with WXG DUF4140 PF13600.6 ORY37920.1 - 8.2 6.9 29.2 0.98 9.9 4.1 5.2 2 1 2 4 4 3 0 N-terminal domain of unknown function (DUF4140) Exonuc_VII_L PF02601.15 ORY37920.1 - 9.2 5.7 20.9 3.4e+02 0.6 21.2 2.1 1 1 0 1 1 1 0 Exonuclease VII, large subunit RasGEF PF00617.19 ORY37921.1 - 1.8e-40 139.0 0.0 3.4e-40 138.1 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain peroxidase PF00141.23 ORY37924.1 - 2.3e-82 276.1 0.0 1.2e-52 178.8 0.0 3.1 2 1 0 2 2 2 2 Peroxidase RBP_receptor PF14752.6 ORY37925.1 - 5.6e-24 84.7 17.4 1.6e-23 83.1 17.0 1.9 1 1 0 1 1 1 1 Retinol binding protein receptor AAA PF00004.29 ORY37926.1 - 1.7e-14 54.4 0.0 3.2e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY37926.1 - 4.8e-13 49.8 0.0 2.4e-11 44.3 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY37926.1 - 1.5e-09 38.2 0.0 5.3e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_lid_10 PF17872.1 ORY37926.1 - 9e-07 28.9 4.2 1e-06 28.7 0.2 2.5 3 0 0 3 3 2 1 AAA lid domain YL1 PF05764.13 ORY37926.1 - 0.00058 20.0 8.4 0.00084 19.5 8.4 1.1 1 0 0 1 1 1 1 YL1 nuclear protein AAA_11 PF13086.6 ORY37926.1 - 0.0013 18.6 3.6 0.063 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 ORY37926.1 - 0.0026 17.7 0.0 0.0083 16.0 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.6 ORY37926.1 - 0.0027 18.0 0.1 0.0089 16.4 0.1 1.9 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 ORY37926.1 - 0.0039 17.1 0.1 0.015 15.2 0.1 1.9 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea PIF1 PF05970.14 ORY37926.1 - 0.0059 15.8 0.1 0.011 14.9 0.1 1.4 1 0 0 1 1 1 1 PIF1-like helicase SDA1 PF05285.12 ORY37926.1 - 0.029 13.8 8.8 0.045 13.2 8.8 1.2 1 0 0 1 1 1 0 SDA1 TniB PF05621.11 ORY37926.1 - 0.05 13.0 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Viral_helicase1 PF01443.18 ORY37926.1 - 0.056 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 ORY37926.1 - 0.068 13.1 0.1 0.17 11.7 0.1 1.7 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.22 ORY37926.1 - 0.074 13.4 0.0 0.25 11.8 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Nop14 PF04147.12 ORY37926.1 - 0.074 11.3 7.7 0.097 10.9 7.7 1.1 1 0 0 1 1 1 0 Nop14-like family AAA_30 PF13604.6 ORY37926.1 - 0.087 12.5 0.8 0.14 11.8 0.1 1.7 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 ORY37926.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cdc6_C PF09079.11 ORY37926.1 - 0.15 12.1 0.0 0.43 10.6 0.0 1.8 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain DNA_pol_phi PF04931.13 ORY37926.1 - 0.22 9.6 11.3 0.36 8.9 11.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 ORY37926.1 - 0.39 9.0 10.5 0.55 8.5 10.5 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 ORY37926.1 - 1.7 7.1 9.7 2.5 6.6 9.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 VCX_VCY PF15231.6 ORY37929.1 - 0.01 16.5 0.3 0.014 16.1 0.3 1.2 1 0 0 1 1 1 0 Variable charge X/Y family LRR_8 PF13855.6 ORY37930.1 - 4.6e-23 80.7 35.1 1.6e-09 37.3 0.3 5.8 2 2 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 ORY37930.1 - 5.3e-19 68.0 34.1 5.1e-05 23.6 0.1 7.7 1 1 7 10 10 10 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY37930.1 - 3.7e-10 38.9 36.6 1.4 9.7 0.1 10.7 11 1 0 11 11 11 6 Leucine Rich Repeat PAC2 PF09754.9 ORY37931.1 - 4.4e-12 46.5 0.0 6e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 PAC2 family DHHA2 PF02833.14 ORY37931.1 - 0.077 13.2 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 DHHA2 domain Nepo_coat_N PF03689.15 ORY37931.1 - 0.099 12.6 0.0 0.37 10.8 0.0 1.8 2 0 0 2 2 2 0 Nepovirus coat protein, N-terminal domain SET PF00856.28 ORY37932.1 - 0.03 14.7 0.0 6.5 7.1 0.0 2.7 2 1 0 2 2 2 0 SET domain LPMO_10 PF03067.15 ORY37933.1 - 0.0038 17.9 0.0 0.031 15.0 0.0 2.5 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading BNR PF02012.20 ORY37933.1 - 0.11 12.6 4.2 0.26 11.4 0.6 3.2 2 0 0 2 2 2 0 BNR/Asp-box repeat Cupin_8 PF13621.6 ORY37935.1 - 2.4e-56 191.3 0.0 3.1e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 ORY37935.1 - 0.0002 20.9 0.0 0.00038 20.0 0.0 1.5 1 1 0 1 1 1 1 Cupin superfamily protein Pirin PF02678.16 ORY37936.1 - 1.8e-24 85.8 0.2 4.8e-24 84.4 0.2 1.8 1 1 0 1 1 1 1 Pirin Pirin_C PF05726.13 ORY37936.1 - 2.6e-21 75.9 0.0 8.3e-21 74.3 0.0 1.8 2 0 0 2 2 2 1 Pirin C-terminal cupin domain UQ_con PF00179.26 ORY37937.1 - 1.7e-24 86.1 0.1 2.8e-24 85.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY37937.1 - 0.015 15.6 0.0 0.031 14.5 0.0 1.8 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 ORY37937.1 - 0.016 15.0 0.4 0.097 12.5 0.4 2.2 1 1 0 1 1 1 0 UEV domain Prok-E2_B PF14461.6 ORY37937.1 - 0.024 14.3 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Ank_4 PF13637.6 ORY37940.1 - 9e-15 54.8 0.8 0.0039 17.7 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY37940.1 - 1.8e-11 44.4 0.9 0.0029 18.1 0.1 4.3 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY37940.1 - 1.4e-08 34.8 0.0 0.036 14.4 0.0 4.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY37940.1 - 3.1e-08 33.7 1.4 0.98 10.0 0.0 6.6 6 0 0 6 6 6 1 Ankyrin repeat Ank_3 PF13606.6 ORY37940.1 - 7.9e-07 28.9 1.3 35 5.4 0.0 7.3 7 0 0 7 7 7 0 Ankyrin repeat F-box-like PF12937.7 ORY37940.1 - 0.14 12.1 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 F-box-like RusA PF05866.11 ORY37940.1 - 0.24 11.9 0.2 0.44 11.1 0.2 1.3 1 0 0 1 1 1 0 Endodeoxyribonuclease RusA MORN PF02493.20 ORY37941.1 - 4.9e-43 142.5 71.6 5.4e-07 29.1 1.4 11.5 12 0 0 12 12 12 10 MORN repeat TRAPPC10 PF12584.8 ORY37942.1 - 1e-12 48.0 0.0 4.6e-12 45.9 0.0 2.0 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 ORY37942.1 - 0.00033 20.3 0.0 0.00051 19.7 0.0 1.2 1 0 0 1 1 1 1 Foie gras liver health family 1 NUDIX PF00293.28 ORY37943.1 - 0.19 11.8 0.0 0.33 11.0 0.0 1.6 1 1 0 1 1 1 0 NUDIX domain FA_hydroxylase PF04116.13 ORY37945.1 - 1.1e-25 90.4 6.5 1.1e-25 90.4 6.5 2.5 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily AA_kinase PF00696.28 ORY37946.1 - 8.6e-35 120.5 0.2 1.5e-34 119.7 0.2 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 ORY37946.1 - 8.5e-16 57.7 1.5 1.7e-15 56.7 1.5 1.6 1 0 0 1 1 1 1 PUA domain Hydrolase_6 PF13344.6 ORY37948.1 - 1.9e-22 79.2 0.0 3.2e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY37948.1 - 3.8e-19 68.5 0.0 9.2e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 ORY37948.1 - 0.004 17.5 0.3 0.94 9.7 0.0 3.0 3 1 1 4 4 4 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORY37948.1 - 0.0096 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Asn_synthase PF00733.21 ORY37949.1 - 5.3e-86 289.5 1.2 1e-52 180.0 0.0 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 ORY37949.1 - 1.4e-38 131.6 0.0 2.3e-38 130.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ORY37949.1 - 2.4e-30 105.5 0.0 3.9e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 ORY37949.1 - 1.6e-07 31.1 0.0 3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 ORY37949.1 - 0.026 13.7 0.0 0.058 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD synthase Pirin_C PF05726.13 ORY37950.1 - 1.9e-24 86.0 0.0 7.3e-24 84.1 0.0 2.0 3 0 0 3 3 3 1 Pirin C-terminal cupin domain Pirin PF02678.16 ORY37950.1 - 3.1e-23 81.8 0.1 6.4e-23 80.8 0.1 1.5 1 0 0 1 1 1 1 Pirin S10_plectin PF03501.15 ORY37951.1 - 2e-41 139.9 0.2 2.5e-41 139.6 0.2 1.1 1 0 0 1 1 1 1 Plectin/S10 domain HBM PF16591.5 ORY37952.1 - 0.029 13.8 0.5 0.044 13.2 0.5 1.3 1 0 0 1 1 1 0 Helical bimodular sensor domain P22_AR_C PF10548.9 ORY37952.1 - 0.032 14.4 0.7 6.1 7.1 0.0 2.3 1 1 1 2 2 2 0 P22AR C-terminal domain DUF745 PF05335.13 ORY37952.1 - 0.49 10.1 5.1 1.5 8.5 5.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF745) CENP-K PF11802.8 ORY37952.1 - 0.67 9.5 10.1 1.1 8.7 10.1 1.3 1 0 0 1 1 1 0 Centromere-associated protein K Pirin_C PF05726.13 ORY37954.1 - 4.2e-24 84.9 0.0 1.5e-23 83.1 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Pirin PF02678.16 ORY37954.1 - 6.9e-23 80.7 0.0 1.4e-22 79.7 0.0 1.6 1 0 0 1 1 1 1 Pirin CDC73_C PF05179.14 ORY37954.1 - 0.0052 16.5 0.1 0.0093 15.7 0.1 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal WW PF00397.26 ORY37955.1 - 2.1e-06 27.7 4.1 4.6e-06 26.6 4.1 1.6 1 0 0 1 1 1 1 WW domain DUF2157 PF09925.9 ORY37955.1 - 0.0018 18.1 0.1 2.1 8.2 0.0 2.2 2 0 0 2 2 2 2 Predicted membrane protein (DUF2157) DUF3318 PF11780.8 ORY37955.1 - 0.0036 17.3 2.2 1.1 9.2 0.4 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3318) DUF3759 PF12585.8 ORY37955.1 - 0.013 15.5 7.6 0.33 11.0 1.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3759) DUF4202 PF13875.6 ORY37955.1 - 1.6 8.6 6.2 1.6 8.6 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4202) LicD PF04991.13 ORY37956.1 - 0.055 13.6 0.5 0.081 13.1 0.5 1.1 1 0 0 1 1 1 0 LicD family Bromodomain PF00439.25 ORY37957.1 - 1.6e-39 133.8 0.0 5.7e-19 68.0 0.0 3.4 3 0 0 3 3 3 2 Bromodomain BET PF17035.5 ORY37957.1 - 7e-21 74.2 0.7 1.5e-20 73.1 0.7 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Rtf2 PF04641.12 ORY37957.1 - 2.1 7.7 7.1 3.3 7.0 7.1 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Ribosomal_S15 PF00312.22 ORY37957.1 - 3.9 7.8 8.5 0.16 12.2 2.4 1.8 2 0 0 2 2 2 0 Ribosomal protein S15 RasGEF PF00617.19 ORY37958.1 - 2.9e-47 161.1 0.0 4.8e-47 160.4 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain FlxA PF14282.6 ORY37959.1 - 0.02 14.8 12.8 0.02 14.8 12.8 2.6 2 1 0 2 2 2 0 FlxA-like protein HSBP1 PF06825.12 ORY37959.1 - 0.065 13.1 7.4 0.21 11.5 0.2 3.3 4 0 0 4 4 4 0 Heat shock factor binding protein 1 SseC PF04888.12 ORY37959.1 - 0.12 12.0 8.8 0.14 11.7 8.8 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DAP_B PF07930.12 ORY37959.1 - 0.8 9.7 3.8 1.1 9.2 3.8 1.3 1 0 0 1 1 1 0 D-aminopeptidase, domain B ABC_tran_CTD PF16326.5 ORY37959.1 - 6 7.2 19.6 2.3 8.5 8.8 3.6 1 1 0 2 2 2 0 ABC transporter C-terminal domain zf-HIT PF04438.16 ORY37960.1 - 6.2e-10 38.8 13.7 9.9e-10 38.1 13.7 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-C2H2_4 PF13894.6 ORY37960.1 - 1.3 10.1 10.5 1.5 9.9 5.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger YL1_C PF08265.11 ORY37960.1 - 1.9 8.3 7.7 1.8 8.4 6.0 1.9 2 1 0 2 2 2 0 YL1 nuclear protein C-terminal domain RNF220 PF15926.5 ORY37961.1 - 4.3e-21 75.7 5.1 4.3e-21 75.7 5.1 2.3 2 1 0 2 2 2 1 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_2 PF13923.6 ORY37961.1 - 1e-10 41.3 11.1 1e-10 41.3 11.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_clus PF00172.18 ORY37961.1 - 1.9e-05 24.7 9.0 1.9e-05 24.7 9.0 2.5 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C3HC4 PF00097.25 ORY37961.1 - 0.00015 21.5 9.6 0.00015 21.5 9.6 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY37961.1 - 0.0013 18.6 9.1 0.0013 18.6 9.1 2.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY37961.1 - 0.0024 17.7 9.3 0.0024 17.7 9.3 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY37961.1 - 0.023 15.0 11.4 0.023 15.0 11.4 3.1 3 0 0 3 3 3 0 Ring finger domain CAP_N PF01213.19 ORY37961.1 - 0.13 11.7 1.9 0.26 10.8 1.9 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TMEM89 PF15098.6 ORY37961.1 - 0.16 12.2 0.9 0.98 9.6 0.5 2.2 1 1 1 2 2 2 0 TMEM89 protein family zf-Nse PF11789.8 ORY37961.1 - 0.76 9.6 6.0 2.3 8.1 6.0 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF640 PF04852.12 ORY37962.1 - 9.8e-08 32.2 0.1 5.2e-06 26.7 0.1 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF640) A_deaminase PF00962.22 ORY37962.1 - 0.076 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Adenosine/AMP deaminase Swi3 PF07962.12 ORY37964.1 - 5.5e-22 77.6 0.2 8.7e-22 76.9 0.2 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Glyco_hydro_46 PF01374.18 ORY37965.1 - 9.3e-24 84.2 0.0 2.1e-23 83.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 46 7tm_1 PF00001.21 ORY37966.1 - 1.9e-05 24.1 8.7 6.1e-05 22.5 8.0 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 ORY37967.1 - 0.00013 21.4 0.8 0.00016 21.1 0.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 ORY37968.1 - 0.0016 17.9 1.5 0.0022 17.4 1.5 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Oxidored_q2 PF00420.24 ORY37968.1 - 0.03 13.9 0.5 0.1 12.3 0.1 2.0 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 7tm_1 PF00001.21 ORY37969.1 - 0.0041 16.5 10.8 0.016 14.5 10.7 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) MeaB PF03308.16 ORY37970.1 - 3.5e-63 213.1 0.0 4.1e-63 212.9 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 ORY37970.1 - 0.035 13.7 0.1 0.1 12.2 0.1 1.8 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 ORY37971.1 - 2e-25 89.3 0.3 3.3e-25 88.6 0.3 1.3 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_24 PF13479.6 ORY37971.1 - 0.0047 16.7 0.1 0.0058 16.4 0.1 1.1 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 ORY37971.1 - 0.0053 16.6 0.0 0.0095 15.7 0.0 1.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ParA PF10609.9 ORY37971.1 - 0.011 15.2 0.1 0.015 14.8 0.1 1.1 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase KAP_NTPase PF07693.14 ORY37971.1 - 0.014 14.6 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain IstB_IS21 PF01695.17 ORY37971.1 - 0.016 15.0 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ArsA_ATPase PF02374.15 ORY37971.1 - 0.017 14.3 0.1 0.026 13.7 0.1 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_22 PF13401.6 ORY37971.1 - 0.035 14.4 0.1 0.097 12.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 ORY37971.1 - 0.046 13.8 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_10 PF12846.7 ORY37971.1 - 0.095 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_30 PF13604.6 ORY37971.1 - 0.11 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ORY37971.1 - 0.13 12.4 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 ORY37971.1 - 0.17 11.4 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain 7tm_1 PF00001.21 ORY37973.1 - 0.00029 20.2 2.7 0.00056 19.3 2.7 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Methyltransf_25 PF13649.6 ORY37974.1 - 1.2e-08 35.5 0.1 1.8e-08 34.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY37974.1 - 6e-07 29.4 0.0 1.8e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY37974.1 - 7.3e-07 29.8 0.1 1.2e-06 29.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY37974.1 - 8.2e-05 22.4 0.0 9.8e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 ORY37974.1 - 0.00042 19.8 0.0 0.00052 19.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB TPMT PF05724.11 ORY37974.1 - 0.0013 18.5 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Clc-like PF07062.12 ORY37976.1 - 0.11 12.0 0.5 0.37 10.2 0.0 2.0 2 0 0 2 2 2 0 Clc-like GIT_SHD PF08518.11 ORY37977.1 - 1e-07 31.4 3.2 0.00052 19.6 0.4 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT HALZ PF02183.18 ORY37977.1 - 1.1e-06 28.7 12.1 4.5e-05 23.6 0.3 5.7 4 1 1 5 5 5 2 Homeobox associated leucine zipper Spc7 PF08317.11 ORY37977.1 - 0.00037 19.5 5.0 0.00037 19.5 5.0 5.1 3 1 1 5 5 5 1 Spc7 kinetochore protein ATG16 PF08614.11 ORY37977.1 - 0.00057 20.2 3.1 0.00057 20.2 3.1 4.6 2 1 2 4 4 4 1 Autophagy protein 16 (ATG16) Fez1 PF06818.15 ORY37977.1 - 0.0037 17.7 9.6 0.0037 17.7 9.6 4.3 1 1 2 3 3 2 1 Fez1 Mod_r PF07200.13 ORY37977.1 - 0.0072 16.4 0.9 0.0072 16.4 0.9 5.2 4 1 1 5 5 5 1 Modifier of rudimentary (Mod(r)) protein ZapB PF06005.12 ORY37977.1 - 0.011 16.2 33.1 1.8 9.0 0.3 8.3 5 2 3 8 8 7 0 Cell division protein ZapB DUF4201 PF13870.6 ORY37977.1 - 0.055 13.2 19.5 0.024 14.4 1.3 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) ADIP PF11559.8 ORY37977.1 - 0.065 13.3 27.2 0.075 13.1 1.7 3.9 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding APC_N_CC PF16689.5 ORY37977.1 - 0.18 11.9 6.2 0.27 11.3 0.2 3.7 3 0 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain Snapin_Pallidin PF14712.6 ORY37977.1 - 0.56 10.7 13.7 0.029 14.8 2.6 4.1 4 1 0 4 4 4 0 Snapin/Pallidin Vir_act_alpha_C PF10400.9 ORY37977.1 - 1.6 9.4 7.2 3.2 8.5 0.0 4.4 4 1 0 4 4 3 0 Virulence activator alpha C-term HMMR_N PF15905.5 ORY37977.1 - 3.9 6.8 31.5 0.035 13.6 13.9 3.5 4 0 0 4 4 4 0 Hyaluronan mediated motility receptor N-terminal GAS PF13851.6 ORY37977.1 - 5.3 6.3 33.5 2 7.7 1.0 4.5 3 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding NYD-SP28_assoc PF14775.6 ORY37977.1 - 6 7.0 6.8 21 5.3 0.5 3.3 3 0 0 3 3 3 0 Sperm tail C-terminal domain DUF948 PF06103.11 ORY37977.1 - 7.8 6.8 22.2 17 5.8 1.9 6.7 4 4 2 6 6 6 0 Bacterial protein of unknown function (DUF948) YabA PF06156.13 ORY37977.1 - 8.1 7.2 22.0 29 5.4 0.3 5.8 2 1 2 4 4 4 0 Initiation control protein YabA B12D PF06522.11 ORY37978.1 - 3.7e-14 52.3 0.0 4.2e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit E1-E2_ATPase PF00122.20 ORY37979.1 - 9.6e-46 155.6 3.2 9.6e-46 155.6 3.2 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORY37979.1 - 5.9e-19 69.2 0.1 1.5e-18 67.9 0.1 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY37979.1 - 1.9e-11 43.5 0.0 1.3e-10 40.8 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.21 ORY37979.1 - 0.00067 19.4 9.3 0.00067 19.4 9.3 2.6 2 1 1 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORY37979.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY37979.1 - 0.021 14.6 0.2 0.06 13.1 0.1 1.8 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.12 ORY37979.1 - 1.4 8.9 6.5 0.16 11.9 0.4 2.6 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Rgp1 PF08737.10 ORY37980.1 - 4.2e-20 72.3 0.0 5.2e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Rgp1 Zn_clus PF00172.18 ORY37981.1 - 5.7e-05 23.2 8.0 0.00013 22.0 8.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 ORY37982.1 - 0.00014 21.9 10.8 0.00014 21.9 10.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 ORY37983.1 - 7.3e-27 94.4 0.0 8.8e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY37983.1 - 1.7e-16 60.3 0.0 2e-16 60.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY37983.1 - 8.9e-11 41.2 0.0 1.2e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY37983.1 - 0.00062 19.8 0.1 0.0057 16.6 0.1 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 ORY37983.1 - 0.016 14.2 0.1 0.023 13.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 ORY37983.1 - 0.05 12.9 0.2 0.11 11.8 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ctr PF04145.15 ORY37985.1 - 9.9e-13 49.0 0.2 1.3e-12 48.6 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF3613 PF12266.8 ORY37985.1 - 0.11 12.3 0.2 0.15 11.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) Metallophos PF00149.28 ORY37986.1 - 2.8e-26 93.3 13.3 6.5e-13 49.6 3.3 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos PF00149.28 ORY37987.1 - 1.7e-27 97.2 15.5 9.9e-14 52.3 5.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Ecm29 PF13001.7 ORY37989.1 - 4.1e-120 401.8 5.4 1.5e-115 386.7 5.0 3.9 3 1 1 4 4 4 2 Proteasome stabiliser HEAT_2 PF13646.6 ORY37989.1 - 6.9e-16 58.4 1.8 0.025 14.9 0.1 10.5 11 1 2 13 13 13 2 HEAT repeats HEAT PF02985.22 ORY37989.1 - 2.9e-14 51.9 5.2 0.28 11.5 0.0 11.5 15 0 0 15 15 15 3 HEAT repeat HEAT_EZ PF13513.6 ORY37989.1 - 1.8e-08 34.7 7.2 0.017 15.6 0.0 7.9 9 0 0 9 9 9 1 HEAT-like repeat IFRD PF05004.13 ORY37989.1 - 1e-06 28.1 5.6 1.4 8.0 0.0 6.6 6 2 0 6 6 6 3 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 ORY37989.1 - 2.2e-06 28.2 0.0 0.25 12.0 0.0 6.1 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 ORY37989.1 - 0.00012 22.2 0.4 0.18 11.8 0.0 5.3 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 ORY37989.1 - 0.00061 19.0 1.5 1.6 7.8 0.0 4.6 4 1 0 4 4 4 2 RNAPII transcription regulator C-terminal Cnd3 PF12719.7 ORY37989.1 - 0.024 13.9 0.6 1.4 8.0 0.0 3.7 4 0 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain DUF5392 PF17370.2 ORY37989.1 - 0.41 10.7 2.4 0.3 11.2 0.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5392) RSN1_7TM PF02714.15 ORY37990.1 - 8.9e-72 241.7 29.3 2.3e-71 240.3 29.3 1.7 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ORY37990.1 - 2.6e-29 102.0 6.0 2.6e-29 102.0 6.0 3.6 5 0 0 5 5 5 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 ORY37990.1 - 1.2e-20 74.5 0.4 1.2e-15 58.2 0.5 2.4 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter SRP1_TIP1 PF00660.17 ORY37990.1 - 0.025 14.7 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 Seripauperin and TIP1 family RRM_1 PF00076.22 ORY37990.1 - 0.095 12.5 0.2 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GOLGA2L5 PF15070.6 ORY37992.1 - 0.058 12.1 0.2 0.065 11.9 0.2 1.0 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Rx_N PF18052.1 ORY37992.1 - 0.093 13.0 0.2 0.13 12.6 0.2 1.1 1 0 0 1 1 1 0 Rx N-terminal domain FMO-like PF00743.19 ORY37994.1 - 7.4e-34 117.1 0.0 1.1e-23 83.5 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like DAO PF01266.24 ORY37994.1 - 2.5e-09 37.2 0.0 5.7e-06 26.2 0.1 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY37994.1 - 2e-07 31.2 0.0 4.5e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ORY37994.1 - 5.3e-06 25.8 0.0 0.0088 15.2 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 ORY37994.1 - 9.4e-06 25.1 0.0 0.00022 20.5 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY37994.1 - 2.4e-05 24.4 1.4 0.00099 19.1 0.1 3.1 3 1 1 4 4 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 ORY37994.1 - 3e-05 23.4 0.0 0.0059 15.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ORY37994.1 - 7.7e-05 22.2 0.0 0.002 17.5 0.0 2.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 ORY37994.1 - 0.0019 17.5 0.0 0.0034 16.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 ORY37994.1 - 0.0027 16.5 0.1 0.0045 15.7 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 ORY37994.1 - 0.0042 16.2 0.0 0.0067 15.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain TTc_toxin_rep PF18807.1 ORY37994.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Tripartite Tc toxins repeat FAD_binding_3 PF01494.19 ORY37994.1 - 0.012 14.9 0.1 0.036 13.3 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 ORY37994.1 - 0.043 14.4 0.2 0.1 13.2 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 ORY37994.1 - 0.16 12.5 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_oxidored PF12831.7 ORY37994.1 - 0.19 11.1 0.1 0.28 10.5 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.20 ORY37994.1 - 0.22 11.6 0.0 1.2 9.2 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 ORY37994.1 - 0.35 10.7 2.8 0.15 12.0 0.4 1.5 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyoxalase PF00903.25 ORY37995.1 - 5.9e-05 23.3 0.1 0.00019 21.6 0.1 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 ORY37995.1 - 0.0058 16.6 0.0 0.014 15.3 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase-like domain DUF604 PF04646.12 ORY37995.1 - 0.025 14.0 0.0 0.03 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF604 Exo_endo_phos PF03372.23 ORY37996.1 - 2e-14 53.7 0.2 3.3e-14 53.0 0.2 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF5344 PF17279.2 ORY37999.1 - 0.0013 19.3 0.2 0.008 16.7 0.2 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5344) DUF599 PF04654.12 ORY38005.1 - 1.3e-52 178.2 4.1 1.9e-52 177.7 4.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF599 DUF4706 PF15797.5 ORY38007.1 - 0.25 11.9 4.5 9.7 6.8 0.7 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4706) ASXH PF13919.6 ORY38007.1 - 0.4 10.7 6.0 0.73 9.8 3.6 2.6 2 1 0 2 2 2 0 Asx homology domain SPA PF08616.10 ORY38008.1 - 7.1e-18 64.6 0.0 1.4e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis DUF2347 PF09804.9 ORY38008.1 - 0.00063 19.4 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF5477 PF17571.2 ORY38009.1 - 0.12 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5477) ZapB PF06005.12 ORY38012.1 - 0.00041 20.7 2.4 0.00055 20.3 2.4 1.3 1 0 0 1 1 1 1 Cell division protein ZapB DUF3450 PF11932.8 ORY38012.1 - 0.0012 18.2 1.3 0.0016 17.8 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Nsp1_C PF05064.13 ORY38012.1 - 0.0013 18.5 1.0 0.0016 18.3 1.0 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region BLOC1_2 PF10046.9 ORY38012.1 - 0.0032 17.7 0.8 0.0041 17.4 0.8 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 ORY38012.1 - 0.0046 16.8 0.8 0.0052 16.7 0.8 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 BST2 PF16716.5 ORY38012.1 - 0.0052 17.3 1.9 0.007 16.9 1.9 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 GAS PF13851.6 ORY38012.1 - 0.0057 16.0 1.8 0.0065 15.8 1.8 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Cluap1 PF10234.9 ORY38012.1 - 0.017 14.5 0.7 0.021 14.2 0.7 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 Herpes_UL6 PF01763.16 ORY38012.1 - 0.018 13.6 0.4 0.02 13.5 0.4 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like APG6_N PF17675.1 ORY38012.1 - 0.02 15.4 1.4 0.025 15.1 1.4 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region CCDC92 PF14916.6 ORY38012.1 - 0.023 14.5 3.3 0.04 13.7 3.2 1.5 1 1 0 1 1 1 0 Coiled-coil domain of unknown function TMF_DNA_bd PF12329.8 ORY38012.1 - 0.033 14.2 2.0 0.052 13.5 1.6 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Fmp27_WPPW PF10359.9 ORY38012.1 - 0.033 13.0 0.9 0.039 12.8 0.9 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Tropomyosin_1 PF12718.7 ORY38012.1 - 0.036 14.2 2.1 0.054 13.7 2.1 1.4 1 1 0 1 1 1 0 Tropomyosin like YabA PF06156.13 ORY38012.1 - 0.039 14.6 1.5 0.046 14.4 1.5 1.2 1 0 0 1 1 1 0 Initiation control protein YabA Sec34 PF04136.15 ORY38012.1 - 0.04 13.8 1.3 0.046 13.6 1.3 1.1 1 0 0 1 1 1 0 Sec34-like family Rab_bind PF16704.5 ORY38012.1 - 0.05 13.7 0.3 3.4 7.8 0.1 2.4 1 1 1 2 2 2 0 Rab binding domain USP8_interact PF08941.10 ORY38012.1 - 0.069 13.0 0.6 0.081 12.7 0.6 1.1 1 0 0 1 1 1 0 USP8 interacting DUF948 PF06103.11 ORY38012.1 - 0.11 12.8 0.4 0.16 12.3 0.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 ORY38012.1 - 0.15 12.2 2.3 0.6 10.3 2.2 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 ORY38012.1 - 0.19 11.9 1.6 0.35 11.1 1.6 1.4 1 0 0 1 1 1 0 Haemolysin XhlA SlyX PF04102.12 ORY38012.1 - 0.38 11.4 4.4 2.5 8.8 4.4 2.0 1 1 0 1 1 1 0 SlyX DivIC PF04977.15 ORY38012.1 - 0.88 9.4 4.3 3.6 7.4 4.3 2.0 1 1 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 ORY38012.1 - 1.5 9.0 3.9 4.6 7.4 1.1 2.3 1 1 1 2 2 2 0 Basic region leucine zipper DUF1796 PF08795.10 ORY38014.1 - 0.077 13.0 0.3 0.28 11.1 0.3 1.9 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) DUF327 PF03885.13 ORY38014.1 - 1.3 9.0 3.8 14 5.7 0.1 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF327) zf-CCCH PF00642.24 ORY38057.1 - 0.066 13.1 4.2 0.11 12.4 4.2 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HSF_DNA-bind PF00447.17 ORY38057.1 - 0.087 13.5 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 HSF-type DNA-binding Dmrt1 PF12374.8 ORY38108.1 - 2 8.9 5.5 0.96 9.9 1.0 2.2 2 0 0 2 2 2 0 Double-sex mab3 related transcription factor 1 zf-CCHC_2 PF13696.6 ORY38109.1 - 0.027 14.3 0.8 0.078 12.8 0.8 1.8 1 0 0 1 1 1 0 Zinc knuckle DASH_Spc34 PF08657.10 ORY38109.1 - 0.11 12.3 0.1 0.3 10.9 0.1 1.6 1 0 0 1 1 1 0 DASH complex subunit Spc34 Pneumo_M2 PF07380.11 ORY38109.1 - 0.13 12.6 0.0 0.52 10.6 0.0 2.1 1 0 0 1 1 1 0 Pneumovirus M2 protein Chitin_synth_2 PF03142.15 ORY38111.1 - 1.1e-205 684.2 0.5 1.3e-205 684.0 0.5 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 ORY38111.1 - 6.7e-13 49.0 1.0 1.3e-12 48.1 1.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY38111.1 - 5.9e-12 46.0 0.1 1.1e-11 45.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ORY38111.1 - 5.8e-05 22.6 0.1 0.034 13.6 0.1 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORY38111.1 - 0.037 13.8 0.0 0.095 12.5 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 Aa_trans PF01490.18 ORY38112.1 - 0.041 12.6 0.3 0.06 12.0 0.3 1.2 1 0 0 1 1 1 0 Transmembrane amino acid transporter protein MBR1 PF17058.5 ORY38112.1 - 0.47 10.7 4.7 1.1 9.6 4.7 1.6 2 0 0 2 2 2 0 Mitochondrial biogenesis regulation protein 1 SLD5_C PF16922.5 ORY38113.1 - 6.1e-11 42.3 0.0 1.3e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 ORY38113.1 - 0.00062 20.2 0.2 0.0011 19.3 0.2 1.5 1 0 0 1 1 1 1 GINS complex protein Ribosomal_S27e PF01667.17 ORY38114.1 - 9.4e-28 95.7 4.2 1.1e-27 95.4 4.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-LSD1 PF06943.12 ORY38114.1 - 0.035 13.9 2.8 0.19 11.6 0.6 2.3 2 0 0 2 2 2 0 LSD1 zinc finger zinc_ribbon_12 PF11331.8 ORY38114.1 - 0.5 10.2 4.1 5 7.0 2.9 2.6 1 1 2 3 3 3 0 Probable zinc-ribbon domain zf-RING_7 PF02591.15 ORY38114.1 - 1 9.6 4.4 18 5.6 0.4 2.6 2 0 0 2 2 2 0 C4-type zinc ribbon domain Arg_tRNA_synt_N PF03485.16 ORY38115.1 - 0.015 15.8 0.1 0.022 15.3 0.1 1.5 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain DUF1192 PF06698.11 ORY38115.1 - 0.066 13.3 3.6 0.065 13.3 1.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) Aminopep PF10023.9 ORY38115.1 - 0.075 12.4 2.4 0.085 12.2 2.4 1.1 1 0 0 1 1 1 0 Putative aminopeptidase ApoO PF09769.9 ORY38115.1 - 0.12 12.3 0.6 0.22 11.5 0.3 1.5 1 1 0 1 1 1 0 Apolipoprotein O KxDL PF10241.9 ORY38115.1 - 0.21 11.9 6.6 0.34 11.2 3.3 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein GrpE PF01025.19 ORY38115.1 - 0.3 10.7 7.4 0.56 9.9 7.4 1.5 1 1 0 1 1 1 0 GrpE Phage_GPO PF05929.11 ORY38115.1 - 0.35 10.4 5.7 0.38 10.3 5.7 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Exonuc_VII_L PF02601.15 ORY38115.1 - 2 7.9 7.3 2.4 7.6 7.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit HSP70 PF00012.20 ORY38116.1 - 1.6e-225 749.9 6.2 2.2e-225 749.4 6.2 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY38116.1 - 2.5e-12 46.3 2.3 3.4e-10 39.2 0.1 2.6 3 0 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.6 ORY38116.1 - 0.0061 17.0 2.4 1.1 9.8 0.3 3.2 3 1 0 3 3 3 2 Cell division protein FtsA PhoH PF02562.16 ORY38116.1 - 0.055 12.9 0.0 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Hydantoinase_A PF01968.18 ORY38116.1 - 0.059 12.6 0.6 5.6 6.1 0.0 2.7 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FGGY_C PF02782.16 ORY38116.1 - 0.17 11.6 0.0 0.63 9.7 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain DSPc PF00782.20 ORY38117.1 - 9.5e-30 103.1 0.0 1.5e-29 102.5 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 ORY38117.1 - 7.8e-05 22.8 0.0 0.00029 21.0 0.0 1.8 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 ORY38117.1 - 0.00024 20.8 0.0 0.00047 19.8 0.0 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 ORY38117.1 - 0.0068 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 ORY38117.1 - 0.058 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 ORY38117.1 - 0.084 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Init_tRNA_PT PF04179.12 ORY38117.1 - 0.093 13.0 0.0 1.1 9.6 0.0 2.1 2 0 0 2 2 2 0 Rit1 DUSP-like domain Ion_trans PF00520.31 ORY38118.1 - 0.0051 16.1 0.5 0.0063 15.8 0.5 1.1 1 0 0 1 1 1 1 Ion transport protein DUF5539 PF17693.1 ORY38118.1 - 0.19 11.4 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5539) Mito_carr PF00153.27 ORY38119.1 - 4.4e-08 32.9 0.2 3.6e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial carrier protein EF1G PF00647.19 ORY38120.1 - 5.2e-42 142.2 0.1 1.2e-41 141.1 0.1 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 ORY38120.1 - 8.8e-20 70.8 0.1 8.8e-20 70.8 0.1 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY38120.1 - 1.8e-14 53.7 0.1 1.8e-14 53.7 0.1 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORY38120.1 - 1.5e-10 41.3 0.0 3.8e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY38120.1 - 4.1e-07 29.9 0.1 1.3e-06 28.3 0.1 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY38120.1 - 1.7e-06 28.1 0.0 5.9e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY38120.1 - 4e-06 27.0 0.0 9.6e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_5 PF18485.1 ORY38120.1 - 0.0014 18.9 0.0 0.0031 17.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 ORY38120.1 - 0.038 13.8 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CPSF100_C PF13299.6 ORY38120.1 - 1.7 8.8 4.8 1.7 8.8 2.5 1.9 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Pox_Ag35 PF03286.14 ORY38120.1 - 1.8 8.3 10.2 3.3 7.5 10.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Proteasome PF00227.26 ORY38121.1 - 7.5e-39 133.2 0.0 8.4e-39 133.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit UQ_con PF00179.26 ORY38122.1 - 1.7e-21 76.3 0.0 2.1e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme EptA_B_N PF08019.12 ORY38123.1 - 0.0062 16.4 1.2 0.0062 16.4 1.2 1.7 2 0 0 2 2 2 1 Phosphoethanolamine transferase EptA/EptB eIF-1a PF01176.19 ORY38125.1 - 7.5e-11 41.7 0.0 1.1e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ArsA_ATPase PF02374.15 ORY38125.1 - 0.0046 16.2 0.0 0.006 15.8 0.0 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase Sec7 PF01369.20 ORY38126.1 - 6e-73 244.4 1.0 1.2e-72 243.5 0.1 2.0 2 0 0 2 2 2 1 Sec7 domain DUF1981 PF09324.10 ORY38126.1 - 6.4e-31 106.0 1.4 1e-28 99.0 0.2 4.3 4 1 1 5 5 5 1 Domain of unknown function (DUF1981) Sec7_N PF12783.7 ORY38126.1 - 2.1e-29 102.5 4.0 2.2e-29 102.4 0.9 2.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 ORY38126.1 - 2.5e-11 43.6 1.0 4.5e-05 23.2 0.1 4.2 4 1 0 4 4 4 2 Dimerisation and cyclophilin-binding domain of Mon2 Cnd1 PF12717.7 ORY38126.1 - 0.034 14.2 0.1 0.89 9.6 0.0 3.0 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 WD40 PF00400.32 ORY38127.1 - 0.041 14.8 0.0 12 6.9 0.0 4.3 5 0 0 5 5 5 0 WD domain, G-beta repeat HAD_2 PF13419.6 ORY38128.1 - 7.8e-23 81.5 0.0 9.4e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY38128.1 - 3.9e-15 56.7 0.0 2.2e-13 51.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY38128.1 - 0.00027 21.4 0.0 0.00038 20.9 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ORY38128.1 - 0.00043 20.4 0.1 0.022 14.8 0.1 2.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY38128.1 - 0.047 13.8 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like HAD_2 PF13419.6 ORY38129.1 - 0.00074 19.6 0.0 0.00088 19.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ORY38129.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase ABC_tran PF00005.27 ORY38130.1 - 1.3e-28 100.2 0.0 2.4e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY38130.1 - 2e-13 50.9 0.5 3.1e-10 40.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 ORY38130.1 - 2.7e-13 49.7 28.6 4.5e-13 49.0 28.6 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.19 ORY38130.1 - 2.1e-06 27.3 0.4 0.0019 17.7 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 ORY38130.1 - 0.0021 17.8 0.1 0.11 12.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 ORY38130.1 - 0.006 17.1 0.0 0.012 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORY38130.1 - 0.01 15.6 0.5 0.033 13.9 0.5 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 ORY38131.1 - 1.6e-21 77.3 0.0 3.9e-21 76.0 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 ORY38131.1 - 1.3e-10 41.6 0.3 2.7e-05 24.1 0.0 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY38131.1 - 0.0025 17.3 0.0 0.14 11.6 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ORY38131.1 - 0.057 13.3 0.2 0.23 11.4 0.1 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 ORY38131.1 - 0.078 13.5 0.1 0.15 12.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain HAD_2 PF13419.6 ORY38132.1 - 3.6e-17 63.0 0.0 4.3e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY38132.1 - 1.7e-07 31.8 0.0 1.6e-06 28.5 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ORY38132.1 - 0.026 14.6 0.1 0.32 11.1 0.1 2.3 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DEAD PF00270.29 ORY38134.1 - 4.6e-40 137.2 0.0 9.1e-40 136.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY38134.1 - 8.6e-31 106.6 0.1 1.4e-29 102.7 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY38134.1 - 0.0016 18.5 0.1 0.017 15.1 0.0 2.8 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY38134.1 - 0.077 13.3 0.6 0.32 11.2 0.2 2.3 2 1 0 2 2 2 0 AAA domain Thiolase_N PF00108.23 ORY38135.1 - 1.6e-10 40.8 0.1 5.2e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY38135.1 - 1.7e-05 24.4 0.3 0.00012 21.7 0.8 2.2 2 1 0 2 2 2 1 Thiolase, C-terminal domain 7tm_1 PF00001.21 ORY38136.1 - 1e-21 77.5 8.3 1.7e-19 70.2 3.6 2.5 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) ECR1_N PF14382.6 ORY38136.1 - 0.025 14.4 0.0 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region PrgI PF12666.7 ORY38136.1 - 2.7 8.7 6.6 0.27 12.0 0.4 2.5 3 0 0 3 3 3 0 PrgI family protein Gti1_Pac2 PF09729.9 ORY38137.1 - 2.6e-19 70.0 0.0 7.5e-18 65.3 0.0 3.9 2 2 1 3 3 3 2 Gti1/Pac2 family AAA PF00004.29 ORY38138.1 - 1.1e-30 106.8 0.0 2.3e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY38138.1 - 2.8e-13 49.4 0.0 6.6e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 ORY38138.1 - 1.1e-07 31.7 0.3 1.3e-06 28.3 0.1 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_14 PF13173.6 ORY38138.1 - 0.041 13.9 0.0 0.084 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Cnn_1N PF07989.11 ORY38139.1 - 1.3e-10 41.3 0.6 1.3e-10 41.3 0.6 9.3 4 2 4 9 9 9 2 Centrosomin N-terminal motif 1 MAD PF05557.13 ORY38139.1 - 0.00052 18.5 24.7 0.00052 18.5 24.7 3.4 2 1 0 3 3 3 2 Mitotic checkpoint protein Fmp27_WPPW PF10359.9 ORY38139.1 - 0.006 15.5 5.2 0.006 15.5 5.2 4.6 2 2 3 5 5 5 1 RNA pol II promoter Fmp27 protein domain Fez1 PF06818.15 ORY38139.1 - 0.036 14.5 68.6 3.8 7.9 2.9 5.9 2 2 2 4 4 4 0 Fez1 TRAF_BIRC3_bd PF16673.5 ORY38139.1 - 0.91 9.4 13.4 0.87 9.4 3.3 3.9 1 1 1 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Golgin_A5 PF09787.9 ORY38139.1 - 1.9 7.9 77.6 0.058 12.8 15.7 5.3 3 2 2 5 5 5 0 Golgin subfamily A member 5 HMMR_N PF15905.5 ORY38139.1 - 1.9 7.8 73.5 0.087 12.3 15.8 4.9 2 2 2 4 4 4 0 Hyaluronan mediated motility receptor N-terminal Fib_alpha PF08702.10 ORY38139.1 - 4.4 7.5 43.4 0.045 13.9 3.8 5.4 3 1 3 6 6 6 0 Fibrinogen alpha/beta chain family F_actin_cap_B PF01115.17 ORY38140.1 - 5.2e-77 258.7 1.1 2.8e-58 197.4 0.3 2.3 1 1 1 2 2 2 2 F-actin capping protein, beta subunit F-actin_cap_A PF01267.17 ORY38140.1 - 0.0053 16.2 0.1 0.016 14.7 0.0 1.8 1 1 1 2 2 2 1 F-actin capping protein alpha subunit AAA_6 PF12774.7 ORY38141.1 - 3.3e-130 433.9 9.1 3.5e-105 351.6 0.0 4.5 5 0 0 5 5 4 2 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 ORY38141.1 - 6.5e-104 348.6 6.4 6.5e-104 348.6 6.4 3.0 3 0 0 3 3 2 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 ORY38141.1 - 1.2e-93 314.4 17.3 1.2e-93 314.4 17.3 4.5 4 1 0 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 ORY38141.1 - 9.8e-74 247.2 0.2 9.8e-74 247.2 0.2 4.0 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 ORY38141.1 - 4e-66 223.0 0.0 2.1e-65 220.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 MT PF12777.7 ORY38141.1 - 4.7e-49 167.3 14.9 4.7e-49 167.3 14.9 2.6 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 ORY38141.1 - 6.6e-44 150.4 0.2 2.2e-43 148.7 0.2 1.9 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 ORY38141.1 - 1.1e-41 142.4 0.0 3.7e-35 121.1 0.0 5.3 6 0 0 6 6 5 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 ORY38141.1 - 8e-36 123.3 0.0 1.9e-35 122.1 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 ORY38141.1 - 6.2e-33 113.7 0.3 3.1e-12 46.7 0.0 6.7 6 1 0 6 6 4 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 ORY38141.1 - 2e-30 105.3 0.0 9.9e-29 99.8 0.0 3.5 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 ORY38141.1 - 9.1e-20 71.1 0.3 1.5e-18 67.1 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 ORY38141.1 - 8.2e-16 58.6 0.0 0.00023 21.6 0.0 5.3 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY38141.1 - 1.3e-14 54.7 1.0 0.012 15.9 0.0 5.8 5 0 0 5 5 4 3 AAA domain AAA_33 PF13671.6 ORY38141.1 - 1e-11 45.2 0.1 0.017 15.3 0.0 5.1 4 0 0 4 4 4 3 AAA domain AAA_18 PF13238.6 ORY38141.1 - 3.2e-10 40.7 3.8 0.051 14.1 0.0 6.9 7 0 0 7 7 5 2 AAA domain AAA_16 PF13191.6 ORY38141.1 - 9.2e-10 39.2 0.5 0.48 10.8 0.0 6.6 6 0 0 6 6 5 1 AAA ATPase domain AAA_lid_1 PF17857.1 ORY38141.1 - 2e-07 31.1 0.1 2e-06 27.9 0.1 2.9 1 0 0 1 1 1 1 AAA+ lid domain T2SSE PF00437.20 ORY38141.1 - 1.3e-06 27.7 0.0 0.0028 16.7 0.0 3.7 3 0 0 3 3 3 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 ORY38141.1 - 3.5e-06 26.6 0.0 0.18 11.2 0.0 4.3 4 0 0 4 4 3 2 FtsK/SpoIIIE family AAA_29 PF13555.6 ORY38141.1 - 3.5e-06 26.7 0.1 0.78 9.5 0.1 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_30 PF13604.6 ORY38141.1 - 4.6e-05 23.2 0.4 14 5.3 0.0 5.0 4 0 0 4 4 4 0 AAA domain Rad17 PF03215.15 ORY38141.1 - 6.1e-05 23.0 0.3 2.3 8.1 0.0 4.6 4 0 0 4 4 4 1 Rad17 P-loop domain AAA_19 PF13245.6 ORY38141.1 - 8e-05 23.0 0.7 0.25 11.7 0.0 5.4 5 0 0 5 5 5 1 AAA domain ABC_tran PF00005.27 ORY38141.1 - 0.00016 22.2 3.6 0.96 10.0 0.0 5.0 5 0 0 5 5 3 1 ABC transporter Mg_chelatase PF01078.21 ORY38141.1 - 0.00024 20.5 4.0 0.82 9.0 0.0 3.8 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 ORY38141.1 - 0.0022 18.4 0.4 16 5.9 0.0 5.5 6 0 0 6 6 5 0 RNA helicase IstB_IS21 PF01695.17 ORY38141.1 - 0.0023 17.7 0.3 0.62 9.8 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein ZapB PF06005.12 ORY38141.1 - 0.0031 17.9 1.9 0.0031 17.9 1.9 6.3 6 0 0 6 6 4 1 Cell division protein ZapB AAA_25 PF13481.6 ORY38141.1 - 0.0036 16.9 0.0 0.67 9.5 0.0 3.8 3 0 0 3 3 3 1 AAA domain TsaE PF02367.17 ORY38141.1 - 0.011 15.8 2.1 18 5.4 0.0 4.5 5 0 0 5 5 5 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 ORY38141.1 - 0.045 13.7 0.8 54 3.7 0.1 4.6 4 0 0 4 4 4 0 NACHT domain AAA_28 PF13521.6 ORY38141.1 - 0.058 13.6 0.1 74 3.5 0.0 4.4 4 0 0 4 4 4 0 AAA domain RuvB_N PF05496.12 ORY38141.1 - 0.075 12.8 0.1 3.1 7.5 0.0 3.1 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 ORY38141.1 - 0.09 12.5 4.0 54 3.4 0.0 4.9 5 0 0 5 5 4 0 AAA domain AAA_21 PF13304.6 ORY38141.1 - 0.091 12.5 0.2 9.6 5.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system SspH PF08141.12 ORY38141.1 - 0.19 11.9 1.4 1.2 9.3 0.2 2.8 2 0 0 2 2 2 0 Small acid-soluble spore protein H family P16-Arc PF04699.14 ORY38142.1 - 4.6e-40 137.5 0.0 5.4e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) CBFD_NFYB_HMF PF00808.23 ORY38143.1 - 1.6e-12 47.6 0.4 1.6e-12 47.6 0.4 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY38143.1 - 8.2e-07 29.5 0.2 8.2e-07 29.5 0.2 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORY38143.1 - 0.0004 20.5 1.5 0.0015 18.6 0.1 2.0 1 1 1 2 2 2 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 ORY38143.1 - 0.01 16.0 0.1 0.023 14.9 0.1 1.6 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) DUF3322 PF11795.8 ORY38143.1 - 0.014 15.5 1.0 0.017 15.1 1.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) CNDH2_C PF16858.5 ORY38143.1 - 0.022 14.6 4.9 0.024 14.5 4.9 1.0 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Sec1 PF00995.23 ORY38143.1 - 0.04 13.2 0.6 0.043 13.0 0.6 1.1 1 0 0 1 1 1 0 Sec1 family Afi1 PF07792.12 ORY38143.1 - 8.4 6.9 9.8 24 5.4 9.8 1.8 1 1 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Methyltransf_21 PF05050.12 ORY38144.1 - 7.3e-15 55.4 0.1 1.1e-14 54.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Peptidase_C58 PF03543.14 ORY38144.1 - 0.00039 20.2 0.0 0.00064 19.5 0.0 1.3 1 0 0 1 1 1 1 Yersinia/Haemophilus virulence surface antigen Methyltransf_23 PF13489.6 ORY38144.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Hydrolase PF00702.26 ORY38145.1 - 5.2e-14 53.0 0.0 1.3e-13 51.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY38145.1 - 0.12 12.0 0.0 0.35 10.6 0.0 1.8 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus Peptidase_C58 PF03543.14 ORY38145.1 - 0.22 11.2 0.3 0.39 10.4 0.3 1.3 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen EamA PF00892.20 ORY38145.1 - 0.29 11.3 11.1 4 7.6 2.8 3.4 3 0 0 3 3 3 0 EamA-like transporter family Xpo1 PF08389.12 ORY38147.1 - 9.1e-06 25.8 1.3 0.00066 19.8 0.2 2.7 2 0 0 2 2 2 1 Exportin 1-like protein Rcd1 PF04078.13 ORY38147.1 - 0.012 14.9 1.2 0.13 11.5 0.2 2.5 2 0 0 2 2 2 0 Cell differentiation family, Rcd1-like DUF3689 PF12463.8 ORY38147.1 - 0.038 13.3 3.0 0.2 10.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3689) IBN_N PF03810.19 ORY38147.1 - 0.038 13.9 0.2 0.2 11.6 0.0 2.3 2 0 0 2 2 2 0 Importin-beta N-terminal domain LRR_4 PF12799.7 ORY38149.1 - 5.7e-14 52.0 15.9 0.00037 20.8 0.0 5.1 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY38149.1 - 2.7e-11 43.1 18.5 2.8e-06 27.0 8.3 4.6 1 1 4 5 5 5 5 Leucine rich repeat LRR_1 PF00560.33 ORY38149.1 - 1.6e-07 30.9 18.5 3.8 8.4 0.0 7.2 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_9 PF14580.6 ORY38149.1 - 0.13 11.7 4.3 0.44 10.0 0.3 2.8 3 0 0 3 3 3 0 Leucine-rich repeat LRR_2 PF07723.13 ORY38149.1 - 0.81 10.5 4.8 22 5.9 0.2 3.5 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 ORY38149.1 - 3 8.1 21.4 9.5 6.6 0.7 6.2 6 0 0 6 6 6 0 Leucine Rich repeat DAD PF02109.16 ORY38150.1 - 0.079 13.3 2.4 0.24 11.7 2.6 1.7 1 1 1 2 2 2 0 DAD family Tetraspanin PF00335.20 ORY38151.1 - 0.53 9.9 4.6 0.34 10.6 3.4 1.3 1 1 0 1 1 1 0 Tetraspanin family MtN3_slv PF03083.16 ORY38151.1 - 1.3 9.1 10.3 10 6.2 1.6 3.3 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange MscL PF01741.18 ORY38155.1 - 6.9e-17 61.9 0.3 9.5e-17 61.4 0.3 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL UPF0547 PF10571.9 ORY38155.1 - 0.0075 16.3 4.3 0.013 15.6 4.3 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 DZR PF12773.7 ORY38155.1 - 0.062 13.3 0.6 0.13 12.4 0.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon DUF4054 PF13262.6 ORY38156.1 - 0.026 14.6 0.8 0.03 14.3 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) SSP160 PF06933.11 ORY38156.1 - 0.42 8.8 10.0 0.45 8.7 10.0 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF515 PF04415.12 ORY38156.1 - 1.8 6.9 6.1 2.1 6.7 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Bud13 PF09736.9 ORY38157.1 - 3.1e-24 86.0 8.3 3.1e-24 86.0 8.3 2.2 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex PG_binding_4 PF12229.8 ORY38157.1 - 0.085 13.1 0.1 2.4 8.5 0.0 2.3 2 0 0 2 2 2 0 Putative peptidoglycan binding domain CAF20 PF17052.5 ORY38157.1 - 0.94 9.6 6.5 0.56 10.4 0.1 2.6 2 1 1 3 3 3 0 Cap associated factor SSP160 PF06933.11 ORY38159.1 - 0.81 7.8 11.0 0.88 7.7 11.0 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF515 PF04415.12 ORY38159.1 - 1.5 7.1 6.0 1.7 7.0 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) CBS PF00571.28 ORY38161.1 - 8.2e-17 61.4 2.5 2.4e-07 31.1 0.1 4.5 4 0 0 4 4 4 4 CBS domain PB1 PF00564.24 ORY38161.1 - 1e-06 28.6 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 PB1 domain HSP70 PF00012.20 ORY38162.1 - 8.5e-14 50.7 0.7 9.1e-14 50.6 0.7 1.0 1 0 0 1 1 1 1 Hsp70 protein DUF2922 PF11148.8 ORY38162.1 - 0.0044 16.7 0.3 0.024 14.3 0.1 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2922) Roughex PF06020.11 ORY38163.1 - 0.3 10.2 2.2 0.38 9.8 2.2 1.1 1 0 0 1 1 1 0 Drosophila roughex protein PB1 PF00564.24 ORY38164.1 - 3.2e-10 39.8 0.4 2.2e-08 33.9 0.0 3.4 3 0 0 3 3 3 1 PB1 domain ZZ PF00569.17 ORY38164.1 - 1.1e-08 34.8 7.6 2.2e-08 33.8 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 ORY38164.1 - 0.0013 19.0 2.8 0.0023 18.2 2.8 1.4 1 0 0 1 1 1 1 C1 domain PB1 PF00564.24 ORY38165.1 - 3e-05 23.9 0.0 4.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 PB1 domain DHquinase_I PF01487.15 ORY38165.1 - 0.11 12.7 0.3 0.17 12.1 0.3 1.4 1 1 0 1 1 1 0 Type I 3-dehydroquinase Cation_efflux PF01545.21 ORY38166.1 - 2.1e-13 50.5 0.2 2.6e-13 50.2 0.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORY38166.1 - 6.2e-07 29.5 0.4 1.5e-05 25.0 0.4 2.4 1 1 0 1 1 1 1 Dimerisation domain of Zinc Transporter HTH_Tnp_1 PF01527.20 ORY38167.1 - 0.055 13.8 0.1 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 Transposase SGT1 PF07093.11 ORY38168.1 - 4.9e-76 256.4 8.0 1.6e-58 198.6 6.5 2.4 2 1 0 2 2 2 2 SGT1 protein MatE PF01554.18 ORY38169.1 - 1.9e-50 170.7 20.8 1.8e-29 102.5 6.1 2.5 3 0 0 3 3 3 2 MatE VTC PF09359.10 ORY38170.1 - 5.8e-76 255.5 0.3 2e-48 165.2 0.0 2.2 1 1 1 2 2 2 2 VTC domain SPX PF03105.19 ORY38170.1 - 1.8e-09 38.0 12.5 0.00011 22.2 0.1 3.3 3 1 0 3 3 3 2 SPX domain DUF202 PF02656.15 ORY38170.1 - 2.2e-07 31.2 0.0 3.6e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Septin PF00735.18 ORY38171.1 - 2.4e-96 322.3 3.5 3.9e-94 315.1 3.5 2.1 1 1 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 ORY38171.1 - 0.0084 16.0 0.3 0.49 10.3 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase Strep_SA_rep PF06696.11 ORY38171.1 - 0.025 14.6 1.7 0.025 14.6 1.7 2.6 2 0 0 2 2 2 0 Streptococcal surface antigen repeat AAA_22 PF13401.6 ORY38171.1 - 0.14 12.4 0.0 0.82 9.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain Strumpellin PF10266.9 ORY38171.1 - 0.27 8.9 3.9 0.44 8.2 3.9 1.2 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin ABC_tran PF00005.27 ORY38171.1 - 0.55 10.7 2.6 2.5 8.6 2.6 2.3 1 1 0 1 1 1 0 ABC transporter MutS_IV PF05190.18 ORY38171.1 - 0.95 9.9 5.0 28 5.1 0.3 3.4 4 0 0 4 4 4 0 MutS family domain IV COG2 PF06148.11 ORY38171.1 - 1 9.4 5.7 4.7 7.3 5.0 2.1 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 PhnG PF06754.12 ORY38171.1 - 1.9 8.4 8.7 12 5.9 5.7 2.6 2 1 1 3 3 3 0 Phosphonate metabolism protein PhnG IFT81_CH PF18383.1 ORY38172.1 - 1.8e-20 73.4 0.0 9.1e-20 71.2 0.0 2.3 1 0 0 1 1 1 1 Intraflagellar transport 81 calponin homology domain DUF4164 PF13747.6 ORY38172.1 - 0.023 15.0 19.7 0.57 10.5 0.2 5.4 4 1 1 5 5 5 0 Domain of unknown function (DUF4164) FAM180 PF15173.6 ORY38172.1 - 0.061 13.3 0.6 0.21 11.6 0.1 2.1 2 0 0 2 2 2 0 FAM180 family Pox_A_type_inc PF04508.12 ORY38172.1 - 1.3 8.9 6.3 3.5 7.6 1.6 3.8 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat NPV_P10 PF05531.12 ORY38172.1 - 3.4 8.2 11.7 46 4.6 0.4 4.9 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 ORY38172.1 - 4.5 6.5 37.4 0.11 11.8 13.6 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) CBS PF00571.28 ORY38174.1 - 1e-17 64.3 1.7 4.6e-07 30.2 0.1 4.4 4 0 0 4 4 4 4 CBS domain 2-ph_phosp PF04029.14 ORY38175.1 - 0.11 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 2-phosphosulpholactate phosphatase Peptidase_S8 PF00082.22 ORY38176.1 - 1.8e-21 76.7 1.2 2.2e-21 76.4 1.2 1.1 1 0 0 1 1 1 1 Subtilase family PA PF02225.22 ORY38176.1 - 5e-06 26.5 0.1 1.2e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 PA domain RRM_1 PF00076.22 ORY38178.1 - 1.5e-35 120.8 0.1 1.1e-23 82.8 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY38178.1 - 0.00023 20.7 0.0 0.41 10.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY38178.1 - 0.0018 18.1 0.0 0.13 12.2 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif DbpA PF03880.15 ORY38178.1 - 0.0053 16.7 0.0 3.8 7.6 0.0 2.3 2 0 0 2 2 2 2 DbpA RNA binding domain Limkain-b1 PF11608.8 ORY38178.1 - 0.011 15.8 0.3 4.4 7.5 0.0 2.5 2 1 0 2 2 2 0 Limkain b1 RRM_Rrp7 PF17799.1 ORY38178.1 - 0.036 13.9 0.0 4.3 7.1 0.0 2.1 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 ORY38178.1 - 0.065 13.3 0.0 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif GRP PF07172.11 ORY38178.1 - 0.43 11.3 20.2 10 6.9 19.1 2.2 2 0 0 2 2 2 0 Glycine rich protein family DUF2427 PF10348.9 ORY38179.1 - 0.2 11.4 4.5 0.93 9.3 2.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) MARVEL PF01284.23 ORY38179.1 - 0.42 10.6 11.5 2.2 8.3 5.3 2.3 1 1 1 2 2 2 0 Membrane-associating domain Na_H_Exchanger PF00999.21 ORY38180.1 - 6.5e-46 156.8 35.3 1.1e-33 116.6 23.9 2.1 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.21 ORY38181.1 - 2.9e-49 167.9 29.2 3.7e-49 167.5 29.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Methyltransf_16 PF10294.9 ORY38182.1 - 0.063 13.0 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase FMN_dh PF01070.18 ORY38183.1 - 9.4e-102 340.6 0.0 1.1e-101 340.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 ORY38183.1 - 1.7e-09 37.3 0.1 2.7e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 ORY38183.1 - 0.0012 17.9 0.2 0.0023 17.0 0.1 1.5 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 ORY38183.1 - 0.057 12.8 0.2 0.085 12.2 0.2 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Arg_repressor_C PF02863.18 ORY38183.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain LpxK PF02606.14 ORY38184.1 - 0.072 12.2 0.2 0.12 11.4 0.2 1.4 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase Ly49 PF08391.10 ORY38185.1 - 0.01 16.2 0.0 0.016 15.6 0.0 1.3 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region LST1 PF05083.13 ORY38185.1 - 0.031 14.5 0.1 0.064 13.5 0.1 1.5 1 0 0 1 1 1 0 LST-1 protein EphA2_TM PF14575.6 ORY38185.1 - 0.14 13.0 0.1 0.27 12.1 0.1 1.4 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAD_binding_3 PF01494.19 ORY38186.1 - 5.4e-30 104.8 0.1 8.5e-30 104.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY38186.1 - 0.0011 18.7 2.2 0.061 12.9 0.9 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY38186.1 - 0.011 15.0 0.3 2.8 7.1 0.1 2.7 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY38186.1 - 0.014 15.6 0.4 0.04 14.1 0.4 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 ORY38186.1 - 0.021 13.9 0.1 0.12 11.5 0.1 2.1 1 1 0 1 1 1 0 Squalene epoxidase Pyr_redox_3 PF13738.6 ORY38186.1 - 0.041 13.1 0.3 3.9 6.6 0.3 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY38186.1 - 0.057 12.5 0.3 0.19 10.8 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein F-box-like PF12937.7 ORY38187.1 - 0.00017 21.4 0.0 0.00036 20.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like Alginate_lyase2 PF08787.11 ORY38188.1 - 2e-21 77.0 0.0 2.7e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Alginate lyase DUF1573 PF07610.11 ORY38188.1 - 0.076 13.1 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) SRP_SPB PF02978.19 ORY38189.1 - 0.12 13.1 6.0 0.12 13.0 2.2 2.5 2 1 0 2 2 2 0 Signal peptide binding domain BK_channel_a PF03493.18 ORY38190.1 - 1.8e-12 47.3 0.0 5.8e-12 45.7 0.0 1.9 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 ORY38190.1 - 2.6e-09 36.9 7.1 2.6e-09 36.9 7.1 2.1 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 ORY38190.1 - 1.4e-08 34.3 22.9 2.9e-08 33.2 22.9 1.4 1 0 0 1 1 1 1 Ion transport protein Castor_Poll_mid PF06241.12 ORY38190.1 - 0.15 12.0 0.0 0.54 10.3 0.0 1.9 2 0 0 2 2 2 0 Castor and Pollux, part of voltage-gated ion channel Lig_chan PF00060.26 ORY38190.1 - 0.6 9.9 5.5 0.054 13.3 0.5 1.8 2 0 0 2 2 2 0 Ligand-gated ion channel MscL PF01741.18 ORY38191.1 - 3.1e-18 66.2 0.9 5.6e-18 65.4 0.9 1.4 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL UPF0547 PF10571.9 ORY38191.1 - 0.059 13.5 5.0 0.11 12.5 5.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 DZR PF12773.7 ORY38191.1 - 0.088 12.8 0.4 0.2 11.7 0.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon LLC1 PF14945.6 ORY38192.1 - 8.5e-10 39.2 5.1 5.1e-08 33.5 4.9 2.4 1 1 0 1 1 1 1 Normal lung function maintenance, Low in Lung Cancer 1 protein FAM183 PF14886.6 ORY38192.1 - 0.00049 20.8 2.1 0.0014 19.4 2.1 2.0 1 1 0 1 1 1 1 FAM183A and FAM183B related Acyl_transf_3 PF01757.22 ORY38193.1 - 0.13 11.3 17.5 0.23 10.5 17.5 1.4 1 1 0 1 1 1 0 Acyltransferase family Ribonuclease_3 PF00636.26 ORY38195.1 - 6.1e-22 78.2 0.5 3.6e-09 37.2 0.0 3.8 2 1 0 2 2 2 2 Ribonuclease III domain DEAD PF00270.29 ORY38195.1 - 9.4e-15 54.8 0.0 8.6e-14 51.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY38195.1 - 1.7e-14 54.1 4.6 2.4e-14 53.6 0.1 3.2 3 1 1 4 4 4 1 Helicase conserved C-terminal domain Ribonucleas_3_3 PF14622.6 ORY38195.1 - 1.2e-12 48.1 0.1 1.6e-05 25.0 0.0 3.5 2 1 0 2 2 2 2 Ribonuclease-III-like ResIII PF04851.15 ORY38195.1 - 1.7e-12 47.7 0.0 4.9e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Dicer_dimer PF03368.14 ORY38195.1 - 3.8e-06 27.0 3.6 8.3e-06 25.9 0.1 3.0 3 0 0 3 3 3 1 Dicer dimerisation domain ABC1 PF03109.16 ORY38195.1 - 2e-05 24.8 0.0 0.00016 21.8 0.0 2.4 1 1 0 1 1 1 1 ABC1 family PAZ PF02170.22 ORY38195.1 - 2.1e-05 24.4 3.8 2.6e-05 24.1 0.2 2.3 2 0 0 2 2 2 1 PAZ domain FAD_binding_3 PF01494.19 ORY38196.1 - 4e-30 105.2 0.1 7.7e-30 104.3 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY38196.1 - 1.5e-05 24.4 1.1 0.027 13.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY38196.1 - 0.0013 19.2 1.0 0.81 10.3 0.3 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY38196.1 - 0.0027 17.4 2.2 0.16 11.5 1.5 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY38196.1 - 0.0082 15.4 0.2 0.66 9.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY38196.1 - 0.0089 16.2 0.2 0.022 15.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORY38196.1 - 0.017 14.2 1.3 0.042 12.9 1.3 1.7 1 0 0 1 1 1 0 FAD binding domain SE PF08491.10 ORY38196.1 - 0.033 13.3 0.1 0.18 10.8 0.1 2.0 1 1 0 1 1 1 0 Squalene epoxidase HI0933_like PF03486.14 ORY38196.1 - 0.053 12.2 0.5 1.6 7.4 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Amino_oxidase PF01593.24 ORY38196.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 ORY38196.1 - 0.12 12.3 0.5 0.22 11.4 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 ORY38196.1 - 0.38 9.8 1.9 0.69 8.9 1.9 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A HAD_2 PF13419.6 ORY38197.1 - 7.4e-25 88.0 0.0 9.1e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY38197.1 - 8.3e-15 55.6 0.1 4e-14 53.4 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ORY38197.1 - 8.3e-05 22.6 0.0 0.065 13.4 0.0 2.8 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY38197.1 - 0.0041 17.5 0.0 0.0056 17.1 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY38197.1 - 0.028 14.5 0.0 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Isy1 PF06246.12 ORY38197.1 - 0.073 12.6 0.0 0.089 12.3 0.0 1.1 1 0 0 1 1 1 0 Isy1-like splicing family Mito_carr PF00153.27 ORY38198.1 - 1.3e-66 220.6 1.7 9e-22 76.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MIP PF00230.20 ORY38199.1 - 2.8e-22 79.6 3.2 4.2e-13 49.5 0.0 2.2 2 0 0 2 2 2 2 Major intrinsic protein PhyH PF05721.13 ORY38199.1 - 0.18 12.1 0.1 0.47 10.7 0.0 1.7 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) LRR_8 PF13855.6 ORY38200.1 - 2e-10 40.3 5.3 3e-05 23.7 0.0 3.2 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 ORY38200.1 - 4.3e-08 33.3 7.1 0.011 16.2 0.9 3.9 3 1 1 4 4 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY38200.1 - 8.8e-06 25.6 7.3 0.055 14.0 0.6 5.1 4 1 0 4 4 4 1 Leucine Rich Repeat F-box PF00646.33 ORY38200.1 - 0.00031 20.5 0.0 0.00094 19.0 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY38200.1 - 0.00055 19.8 0.0 0.0015 18.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like FmiP_Thoc5 PF09766.9 ORY38200.1 - 0.035 13.4 0.4 0.065 12.5 0.3 1.4 1 1 0 1 1 1 0 Fms-interacting protein/Thoc5 FNIP PF05725.12 ORY38200.1 - 0.037 14.2 1.4 11 6.2 0.0 3.5 2 2 0 2 2 2 0 FNIP Repeat DUF4349 PF14257.6 ORY38200.1 - 0.063 12.7 1.8 0.091 12.2 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Syntaxin-6_N PF09177.11 ORY38200.1 - 0.15 12.7 2.3 0.39 11.3 2.1 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Syntaxin PF00804.25 ORY38200.1 - 0.16 11.7 2.3 0.25 11.0 2.3 1.3 1 0 0 1 1 1 0 Syntaxin FliD_N PF02465.18 ORY38200.1 - 0.2 12.4 4.2 0.19 12.4 2.7 1.6 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF3573 PF12097.8 ORY38200.1 - 0.2 10.5 0.5 0.24 10.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) HTH_19 PF12844.7 ORY38200.1 - 0.23 11.5 0.6 4.9 7.2 0.1 2.7 2 1 0 2 2 2 0 Helix-turn-helix domain EMP24_GP25L PF01105.24 ORY38200.1 - 0.31 11.0 2.8 0.26 11.2 1.1 1.6 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD MFS_1 PF07690.16 ORY38201.1 - 1.2e-16 60.6 31.3 2.8e-16 59.4 29.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 ORY38202.1 - 6.7e-17 61.4 21.6 7.3e-17 61.3 20.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.6 ORY38202.1 - 0.042 14.3 7.0 1.2 9.6 0.4 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) MFS_1 PF07690.16 ORY38203.1 - 2e-17 63.2 24.2 2.8e-17 62.7 24.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 ORY38203.1 - 8.8e-10 37.7 2.4 8.8e-10 37.7 2.4 1.6 2 0 0 2 2 2 1 MFS/sugar transport protein Adeno_E3_14_5 PF04834.12 ORY38203.1 - 0.12 12.9 1.1 0.35 11.4 0.9 1.9 1 1 0 1 1 1 0 Early E3 14.5 kDa protein DUF4231 PF14015.6 ORY38203.1 - 9.3 6.8 7.5 6.5 7.3 0.2 3.3 2 2 0 3 3 3 0 Protein of unknown function (DUF4231) DUF393 PF04134.12 ORY38204.1 - 4.8e-11 44.0 0.0 6.4e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF393 DUF4428 PF14471.6 ORY38204.1 - 0.12 12.3 0.1 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) zf-C2H2_2 PF12756.7 ORY38205.1 - 2.3e-33 114.6 3.4 8.8e-30 103.0 1.9 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 ORY38205.1 - 0.0025 18.0 0.6 0.0025 18.0 0.6 3.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding MEDS PF14417.6 ORY38205.1 - 0.032 14.1 0.1 0.28 11.0 0.0 2.4 2 1 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain DUF1460 PF07313.12 ORY38205.1 - 0.048 13.1 0.2 0.6 9.5 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1460) zf-LYAR PF08790.11 ORY38205.1 - 0.12 12.3 3.0 0.54 10.2 0.3 2.7 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_4 PF13894.6 ORY38205.1 - 0.32 12.0 9.5 8.1 7.6 0.4 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY38205.1 - 3.2 8.4 11.0 8.5 7.1 0.6 3.7 3 1 1 4 4 4 0 Zinc finger, C2H2 type DUF4149 PF13664.6 ORY38206.1 - 3.5e-18 65.8 1.9 3.1e-17 62.8 1.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) MtrG PF04210.13 ORY38206.1 - 0.14 12.0 0.1 15 5.5 0.0 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4149 PF13664.6 ORY38207.1 - 1.3e-16 60.8 3.6 1.8e-16 60.3 3.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4149) DUF2678 PF10856.8 ORY38207.1 - 0.032 14.2 0.4 0.095 12.6 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2678) Form-deh_trans PF09163.11 ORY38207.1 - 0.62 9.9 3.1 1.1 9.1 0.0 2.7 3 0 0 3 3 3 0 Formate dehydrogenase N, transmembrane BicD PF09730.9 ORY38208.1 - 0.085 11.3 0.4 0.15 10.5 0.0 1.5 2 0 0 2 2 2 0 Microtubule-associated protein Bicaudal-D F-box-like PF12937.7 ORY38212.1 - 6.3e-07 29.2 1.5 1.5e-06 28.0 1.5 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 ORY38212.1 - 0.0003 21.1 0.0 1.1 9.8 0.0 3.7 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) F-box PF00646.33 ORY38212.1 - 0.0024 17.7 0.7 0.0024 17.7 0.7 2.0 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.6 ORY38212.1 - 0.0066 16.4 0.1 20 5.6 0.0 5.1 7 0 0 7 7 7 1 Leucine Rich repeat 7tm_3 PF00003.22 ORY38214.1 - 6.7e-09 35.8 14.5 1.4e-08 34.8 14.5 1.5 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 ORY38216.1 - 7.8e-08 31.8 0.0 8.4e-08 31.7 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Lipase_3 PF01764.25 ORY38217.1 - 4.1e-17 62.4 0.0 1e-16 61.1 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORY38217.1 - 0.018 15.6 0.2 0.018 15.6 0.2 2.6 2 1 1 3 3 3 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY38217.1 - 0.13 11.5 0.1 0.27 10.4 0.1 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 GHMP_kinases_C PF08544.13 ORY38217.1 - 0.14 12.6 1.3 4 7.9 0.1 2.7 2 0 0 2 2 2 0 GHMP kinases C terminal RNA_pol_N PF01194.17 ORY38218.1 - 1e-30 105.8 1.3 1.1e-30 105.6 1.3 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Brix PF04427.18 ORY38219.1 - 1e-29 104.0 3.5 3.3e-29 102.4 3.5 1.8 1 1 0 1 1 1 1 Brix domain Gti1_Pac2 PF09729.9 ORY38220.1 - 1.7e-12 47.8 0.0 9.6e-11 42.1 0.0 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family FAD_binding_3 PF01494.19 ORY38221.1 - 4e-10 39.5 0.3 1.9e-07 30.7 0.0 3.2 2 1 0 2 2 2 1 FAD binding domain Piwi PF02171.17 ORY38221.1 - 0.0057 15.9 0.0 0.009 15.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain Pyr_redox PF00070.27 ORY38221.1 - 0.15 12.6 0.9 14 6.4 0.0 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY38221.1 - 0.16 11.2 0.6 13 4.9 0.0 2.6 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY38222.1 - 1e-32 113.8 0.7 4.5e-32 111.7 0.7 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY38222.1 - 5.9e-05 22.4 3.5 0.036 13.3 0.7 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY38222.1 - 0.0013 18.4 6.1 0.0032 17.1 3.0 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY38222.1 - 0.0018 18.5 0.1 0.0067 16.6 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 ORY38222.1 - 0.0024 17.0 0.0 0.0097 15.0 0.0 1.8 1 1 0 1 1 1 1 Squalene epoxidase GIDA PF01134.22 ORY38222.1 - 0.016 14.3 0.5 0.024 13.7 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ORY38222.1 - 0.016 14.3 1.7 0.025 13.7 1.7 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 ORY38222.1 - 0.028 15.0 1.2 0.33 11.5 0.3 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY38222.1 - 0.049 12.9 1.3 2.2 7.5 0.6 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY38222.1 - 0.26 9.9 2.1 6.5 5.3 0.5 2.2 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 ORY38222.1 - 0.58 8.9 2.4 3.3 6.5 0.4 2.1 2 0 0 2 2 2 0 Tryptophan halogenase DHC_N2 PF08393.13 ORY38223.1 - 0.023 13.8 0.1 0.031 13.4 0.1 1.2 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 zf-C4H2 PF10146.9 ORY38223.1 - 0.12 12.6 0.1 0.18 12.1 0.1 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein COG6 PF06419.11 ORY38224.1 - 3.6e-113 378.9 0.1 2.1e-83 280.6 0.0 3.4 1 1 2 3 3 3 3 Conserved oligomeric complex COG6 Sec34 PF04136.15 ORY38224.1 - 0.003 17.5 1.3 0.17 11.7 0.1 2.8 2 0 0 2 2 2 1 Sec34-like family Glycos_transf_N PF04413.16 ORY38224.1 - 0.011 15.4 0.1 0.69 9.5 0.0 2.7 2 0 0 2 2 2 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) SKA2 PF16740.5 ORY38224.1 - 0.25 11.1 4.5 11 5.9 0.0 3.7 3 0 0 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF3421 PF11901.8 ORY38225.1 - 2e-14 53.5 0.0 4.6e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3421) ABA_WDS PF02496.16 ORY38225.1 - 0.0011 19.5 1.6 0.0036 17.8 1.6 2.0 1 1 0 1 1 1 1 ABA/WDS induced protein FAD_binding_3 PF01494.19 ORY38226.1 - 2e-29 102.9 0.0 3.5e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY38226.1 - 0.0005 19.4 0.1 0.85 8.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY38226.1 - 0.00085 19.0 3.9 0.076 12.6 2.3 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY38226.1 - 0.0041 17.3 0.3 0.02 15.1 0.4 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 ORY38226.1 - 0.031 13.3 0.0 0.26 10.3 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox PF00070.27 ORY38226.1 - 0.06 13.9 0.1 4 8.1 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ACP_syn_III PF08545.10 ORY38226.1 - 0.06 13.2 4.6 4.5 7.2 0.2 3.9 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Pyr_redox_3 PF13738.6 ORY38226.1 - 0.15 11.2 0.1 13 4.9 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY38227.1 - 2.2e-16 60.1 0.2 3.3e-16 59.5 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY38227.1 - 0.0002 20.7 1.1 0.046 13.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY38227.1 - 0.0082 15.4 1.3 1 8.5 0.9 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY38227.1 - 0.017 14.0 0.7 0.042 12.7 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_8 PF13450.6 ORY38227.1 - 0.02 15.1 0.6 0.038 14.2 0.6 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY38227.1 - 0.027 15.0 0.8 2.9 8.5 0.2 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY38227.1 - 0.049 13.2 6.6 0.52 9.8 6.6 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase ACP_syn_III PF08545.10 ORY38227.1 - 0.079 12.8 0.7 1.9 8.4 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 2-Hacid_dh_C PF02826.19 ORY38227.1 - 0.083 12.2 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 ORY38228.1 - 7.1e-10 38.6 0.0 9e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 ORY38228.1 - 0.05 12.6 0.0 0.066 12.3 0.0 1.1 1 0 0 1 1 1 0 Squalene epoxidase FAD_binding_3 PF01494.19 ORY38229.1 - 4.3e-27 95.3 0.5 1.5e-26 93.5 0.5 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY38229.1 - 0.00044 19.9 2.3 0.014 15.0 1.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY38229.1 - 0.00047 19.5 2.5 0.11 11.7 0.4 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY38229.1 - 0.0033 17.9 0.5 0.68 10.5 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY38229.1 - 0.0055 16.9 0.1 0.011 15.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORY38229.1 - 0.06 12.4 0.4 0.12 11.4 0.4 1.5 1 0 0 1 1 1 0 FAD binding domain DUF1640 PF07798.11 ORY38230.1 - 5.1e-31 108.1 7.5 6.1e-31 107.8 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Sulphotransf PF09037.10 ORY38230.1 - 0.0027 17.3 0.2 0.0036 16.9 0.2 1.2 1 0 0 1 1 1 1 Stf0 sulphotransferase Zot PF05707.12 ORY38230.1 - 0.026 14.2 0.2 0.05 13.2 0.2 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) DotU PF09850.9 ORY38230.1 - 0.036 13.8 0.7 2.1 8.0 0.1 2.2 2 0 0 2 2 2 0 Type VI secretion system protein DotU Baculo_PEP_C PF04513.12 ORY38230.1 - 1.4 8.9 9.1 1.6 8.8 3.7 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cob_adeno_trans PF01923.18 ORY38231.1 - 5.1e-57 192.6 0.0 5.9e-57 192.4 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase PI3_PI4_kinase PF00454.27 ORY38232.1 - 1.9e-51 175.3 0.0 3.2e-51 174.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase NPHI_C PF08469.10 ORY38232.1 - 0.36 10.8 2.2 23 4.9 0.0 2.7 3 0 0 3 3 3 0 Nucleoside triphosphatase I C-terminal FRB_dom PF08771.11 ORY38233.1 - 0.29 11.6 1.7 2.9 8.4 0.1 2.4 1 1 1 2 2 2 0 FKBP12-rapamycin binding domain Pkinase PF00069.25 ORY38234.1 - 5.4e-53 180.0 0.0 1.7e-49 168.5 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY38234.1 - 1.3e-27 96.7 0.0 1.1e-24 87.2 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.6 ORY38234.1 - 3.1e-19 69.0 0.8 1.4e-18 66.9 0.1 2.3 3 0 0 3 3 3 1 PH domain Haspin_kinase PF12330.8 ORY38234.1 - 0.00035 19.6 0.0 0.00075 18.5 0.0 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORY38234.1 - 0.001 18.4 0.0 0.11 11.8 0.0 2.4 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORY38234.1 - 0.0019 17.0 0.0 0.003 16.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 ORY38234.1 - 0.0024 17.5 0.1 0.099 12.2 0.0 2.5 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 ORY38234.1 - 0.089 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY38234.1 - 0.16 11.9 0.0 0.71 9.8 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family FAD_binding_3 PF01494.19 ORY38235.1 - 8.5e-12 45.0 0.0 1.1e-11 44.7 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 ORY38236.1 - 1.2e-30 107.0 0.2 1.5e-30 106.7 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY38236.1 - 1.6e-06 27.6 0.6 0.012 14.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 ORY38236.1 - 0.0063 15.6 0.1 1.1 8.2 0.1 2.4 2 1 0 2 2 2 2 Squalene epoxidase DAO PF01266.24 ORY38236.1 - 0.02 14.5 5.6 0.45 10.1 3.4 2.2 1 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORY38236.1 - 0.022 15.3 0.5 7.4 7.2 0.2 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY38236.1 - 0.027 14.7 0.6 0.1 12.8 0.2 2.2 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ORY38237.1 - 3.6e-29 102.1 0.1 7e-29 101.2 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY38237.1 - 0.0005 19.8 5.9 0.16 11.5 3.6 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY38237.1 - 0.0013 18.0 0.9 0.32 10.2 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY38237.1 - 0.0097 16.1 0.1 0.034 14.4 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 ORY38237.1 - 0.026 13.6 0.0 0.13 11.3 0.0 1.9 1 1 0 1 1 1 0 Squalene epoxidase Trp_halogenase PF04820.14 ORY38237.1 - 0.028 13.3 0.8 0.98 8.2 0.0 2.6 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox PF00070.27 ORY38237.1 - 0.12 13.0 0.4 0.95 10.1 0.1 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY38237.1 - 0.15 11.1 0.8 0.26 10.3 0.8 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 ORY38237.1 - 0.17 10.9 1.8 0.39 9.7 1.8 1.7 1 1 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 ORY38238.1 - 5.3e-29 101.6 0.1 5.1e-28 98.3 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY38238.1 - 0.00035 19.9 2.0 0.21 10.8 0.8 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY38238.1 - 0.00058 20.4 1.1 0.079 13.5 0.7 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 ORY38238.1 - 0.00062 18.9 0.0 0.0022 17.1 0.0 1.9 1 1 0 1 1 1 1 Squalene epoxidase ACP_syn_III PF08545.10 ORY38238.1 - 0.01 15.6 2.9 3.4 7.6 0.1 3.8 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NAD_binding_8 PF13450.6 ORY38238.1 - 0.023 14.9 0.2 0.053 13.8 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY38238.1 - 0.025 14.2 8.1 0.11 12.1 5.4 2.1 1 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY38238.1 - 0.099 11.9 1.2 4.5 6.4 0.7 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ORY38238.1 - 0.14 11.5 0.7 0.25 10.6 0.7 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ORY38238.1 - 0.29 9.8 2.6 11 4.6 0.3 2.7 2 1 0 3 3 3 0 HI0933-like protein FAD_binding_2 PF00890.24 ORY38238.1 - 0.57 9.2 3.2 0.76 8.8 1.8 1.9 2 1 0 2 2 2 0 FAD binding domain Clathrin PF00637.20 ORY38239.1 - 1.1e-25 90.2 0.3 5.2e-25 88.0 0.2 2.0 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.9 ORY38239.1 - 7.4e-05 23.2 0.0 0.00024 21.5 0.0 1.8 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 WD40_like PF17005.5 ORY38239.1 - 0.0005 19.5 0.0 0.018 14.4 0.0 2.3 2 0 0 2 2 2 1 WD40-like domain WD40 PF00400.32 ORY38239.1 - 0.00083 20.1 0.2 0.0064 17.3 0.1 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY38239.1 - 0.033 14.5 0.2 0.29 11.4 0.0 2.5 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain zf-C2HE PF16278.5 ORY38239.1 - 0.085 13.3 0.1 0.27 11.7 0.1 1.8 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger CENP-B_dimeris PF09026.10 ORY38239.1 - 0.12 12.7 5.5 0.28 11.6 5.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 ORY38239.1 - 1.2 9.6 8.7 2.5 8.5 8.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_transf_34 PF05637.12 ORY38241.1 - 1e-14 54.9 2.9 1.3e-07 31.6 0.0 2.1 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family DUF262 PF03235.14 ORY38244.1 - 3.3e-07 30.7 0.4 3.2e-06 27.5 0.4 2.3 1 1 0 1 1 1 1 Protein of unknown function DUF262 CENP-B_dimeris PF09026.10 ORY38244.1 - 3.2 8.2 11.2 0.37 11.2 0.9 3.0 3 0 0 3 3 3 0 Centromere protein B dimerisation domain FAD_binding_3 PF01494.19 ORY38245.1 - 8.8e-18 64.6 0.3 8.4e-17 61.4 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 ORY38245.1 - 0.0045 16.1 0.0 0.011 14.8 0.0 1.6 1 1 0 1 1 1 1 Squalene epoxidase Pkinase_Tyr PF07714.17 ORY38246.1 - 1.7e-42 145.5 0.0 2e-41 142.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 ORY38246.1 - 3.4e-38 131.5 0.0 2.3e-37 128.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Sel1 PF08238.12 ORY38246.1 - 9.5e-14 51.6 1.2 3.7e-05 24.2 0.0 3.5 3 0 0 3 3 3 3 Sel1 repeat TIR_2 PF13676.6 ORY38246.1 - 2.3e-12 47.6 0.0 1.5e-10 41.7 0.0 2.7 2 0 0 2 2 2 1 TIR domain TIR PF01582.20 ORY38246.1 - 0.00045 20.1 0.0 0.00098 19.0 0.0 1.5 1 0 0 1 1 1 1 TIR domain Kinase-like PF14531.6 ORY38246.1 - 0.0025 17.2 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Sel1 PF08238.12 ORY38247.1 - 2.2e-07 31.3 3.0 1.9e-05 25.2 0.3 2.6 3 0 0 3 3 3 2 Sel1 repeat 7tm_1 PF00001.21 ORY38249.1 - 0.033 13.5 14.7 0.049 13.0 13.9 1.6 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) FAD_binding_3 PF01494.19 ORY38250.1 - 0.00093 18.5 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 ORY38250.1 - 0.089 11.8 0.0 3.9 6.4 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase FAD_binding_3 PF01494.19 ORY38251.1 - 3e-20 72.8 0.7 1.9e-11 43.9 0.1 2.8 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ORY38251.1 - 0.0038 17.4 0.1 0.0095 16.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY38251.1 - 0.0094 15.6 0.5 0.015 14.9 0.5 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.10 ORY38251.1 - 0.032 13.3 0.0 0.081 12.0 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox PF00070.27 ORY38251.1 - 0.042 14.4 0.1 0.78 10.3 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY38251.1 - 0.074 12.3 0.0 0.23 10.6 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY38251.1 - 0.077 12.1 0.2 0.13 11.3 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 ORY38252.1 - 9e-23 81.1 0.4 2e-22 79.9 0.4 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY38252.1 - 8e-05 22.0 0.7 0.1 11.8 0.4 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY38252.1 - 0.002 17.8 2.3 0.0051 16.5 1.3 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY38252.1 - 0.0022 18.2 0.2 0.0066 16.7 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY38252.1 - 0.0029 18.1 0.4 0.24 12.0 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY38252.1 - 0.061 12.4 1.7 0.17 10.9 1.7 1.7 1 1 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 ORY38252.1 - 0.11 11.3 0.4 5.7 5.7 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase SE PF08491.10 ORY38252.1 - 0.12 11.4 0.0 1 8.4 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase DHHC PF01529.20 ORY38253.1 - 2.7e-16 59.9 22.6 1.3e-14 54.4 11.4 2.9 3 1 0 3 3 3 2 DHHC palmitoyltransferase Surp PF01805.20 ORY38254.1 - 5.3e-09 35.9 1.2 7.3e-09 35.5 0.1 1.9 2 0 0 2 2 2 1 Surp module CTD_bind PF04818.13 ORY38254.1 - 4.9e-05 24.1 1.2 0.00023 21.9 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase II-binding domain. zf-CCHC PF00098.23 ORY38254.1 - 0.00044 20.2 3.3 0.00044 20.2 3.3 1.7 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 ORY38254.1 - 0.018 14.8 0.5 0.037 13.7 0.5 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger HAT PF02184.16 ORY38255.1 - 2.8e-28 97.5 64.3 5.8e-13 48.6 0.2 13.5 14 2 0 14 14 14 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 ORY38255.1 - 1.6e-22 78.2 12.1 0.0026 18.4 0.5 9.7 7 3 4 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 ORY38255.1 - 4.6e-14 52.7 0.0 0.049 14.1 0.0 7.4 7 1 0 8 8 7 3 Tetratricopeptide repeat Suf PF05843.14 ORY38255.1 - 9.8e-13 48.7 22.9 0.00014 21.9 5.5 7.3 2 1 3 6 6 6 3 Suppressor of forked protein (Suf) TPR_17 PF13431.6 ORY38255.1 - 8.1e-09 35.3 2.3 2.3 8.8 0.0 7.5 8 1 0 8 8 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY38255.1 - 4.7e-07 29.4 12.3 4.7 7.6 0.1 8.4 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY38255.1 - 2.7e-06 27.7 11.9 28 5.6 0.1 9.2 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY38255.1 - 7.7e-06 26.1 8.8 25 5.3 0.0 7.3 7 2 0 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY38255.1 - 4.6e-05 23.2 11.7 2.2 8.5 0.2 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 ORY38255.1 - 0.00053 19.3 10.9 0.74 9.0 0.9 5.0 1 1 5 6 6 6 2 Tetratricopeptide repeat BSD PF03909.17 ORY38255.1 - 0.0041 17.1 1.2 0.065 13.2 0.4 2.8 2 0 0 2 2 2 1 BSD domain T4BSS_DotI_IcmL PF11393.8 ORY38255.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 Type-IV b secretion system, inner-membrane complex component TPR_9 PF13371.6 ORY38255.1 - 0.033 14.3 1.8 2.2 8.5 0.3 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat U3_assoc_6 PF08640.11 ORY38255.1 - 0.26 11.4 16.9 0.37 10.9 0.3 6.1 6 1 1 7 7 7 0 U3 small nucleolar RNA-associated protein 6 TPR_8 PF13181.6 ORY38255.1 - 0.27 11.5 15.9 81 3.8 0.0 8.2 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY38255.1 - 0.34 11.6 10.4 29 5.4 0.1 5.7 7 0 0 7 7 5 0 Tetratricopeptide repeat Alpha_kinase PF02816.18 ORY38256.1 - 2.9e-14 53.6 0.3 4.9e-14 52.9 0.3 1.4 1 1 0 1 1 1 1 Alpha-kinase family DEAD PF00270.29 ORY38320.1 - 2.6e-16 59.9 0.0 5.1e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY38320.1 - 7.3e-16 58.5 0.1 7.5e-13 48.8 0.0 3.9 4 0 0 4 4 4 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 ORY38320.1 - 2e-10 41.2 2.5 6.2e-10 39.7 2.5 1.9 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 ORY38320.1 - 0.0036 17.3 0.0 0.015 15.3 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit BRCA2 PF00634.18 ORY38320.1 - 0.036 13.7 0.3 0.11 12.2 0.3 2.0 1 0 0 1 1 1 0 BRCA2 repeat Zn_clus PF00172.18 ORY38321.1 - 0.00058 19.9 9.3 0.0011 19.0 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_19 PF00182.19 ORY38322.1 - 6.7e-12 45.8 0.1 6.7e-12 45.8 0.1 1.9 2 0 0 2 2 2 1 Chitinase class I GIDA PF01134.22 ORY38322.1 - 0.15 11.1 0.4 0.25 10.4 0.4 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Dicty_REP PF05086.12 ORY38322.1 - 0.15 10.0 8.1 0.19 9.7 8.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 ORY38322.1 - 0.33 10.9 39.6 0.53 10.3 39.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Med13_C PF06333.12 ORY38322.1 - 2.9 7.1 11.9 3.8 6.7 11.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Mito_fiss_reg PF05308.11 ORY38322.1 - 4.8 7.2 5.6 6.9 6.7 5.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DEC-1_N PF04625.13 ORY38322.1 - 8.6 5.3 7.0 11 4.9 7.0 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region COX6A PF02046.15 ORY38323.1 - 0.22 12.0 0.6 0.3 11.6 0.6 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa Glyco_hydro_19 PF00182.19 ORY38325.1 - 3.4e-12 46.7 0.5 4e-11 43.3 0.1 2.6 2 0 0 2 2 2 1 Chitinase class I SOBP PF15279.6 ORY38325.1 - 9.9 6.7 39.0 15 6.1 39.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein SDA1 PF05285.12 ORY38327.1 - 0.011 15.1 49.7 0.015 14.8 49.7 1.2 1 0 0 1 1 1 0 SDA1 GREB1 PF15782.5 ORY38327.1 - 3.9 4.5 21.0 4.8 4.2 21.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Kelch_4 PF13418.6 ORY38328.1 - 3.9e-10 39.6 11.6 6.8e-05 22.8 0.0 4.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 ORY38328.1 - 1.6e-08 34.4 9.3 0.03 14.3 0.1 5.6 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.6 ORY38328.1 - 8.7e-08 32.2 5.7 0.027 14.7 0.1 4.2 2 1 1 3 3 3 3 Kelch motif Kelch_3 PF13415.6 ORY38328.1 - 3.8e-06 27.0 11.4 0.16 12.3 0.1 6.0 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_1 PF01344.25 ORY38328.1 - 0.00024 20.6 1.4 3.7 7.2 0.0 4.2 4 0 0 4 4 4 2 Kelch motif CD34_antigen PF06365.12 ORY38328.1 - 0.0019 17.8 0.0 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family Kelch_2 PF07646.15 ORY38328.1 - 0.011 15.7 0.7 8 6.6 0.0 3.7 3 0 0 3 3 3 0 Kelch motif ENTH PF01417.20 ORY38334.1 - 0.0068 16.4 4.4 0.022 14.8 4.1 1.9 1 1 1 2 2 2 1 ENTH domain Caprin-1_dimer PF18293.1 ORY38334.1 - 0.0085 16.6 2.3 0.028 14.9 1.5 1.9 1 1 1 2 2 2 1 Caprin-1 dimerization domain Prefoldin PF02996.17 ORY38335.1 - 8.7e-14 51.5 0.0 3e-13 49.7 0.0 1.9 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 ORY38335.1 - 7.3e-05 22.8 0.2 0.00036 20.5 0.0 2.4 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.7 ORY38335.1 - 0.00077 20.3 1.7 0.00077 20.3 1.7 8.3 6 2 2 8 8 8 3 Domain of unknown function (DUF3835) Nitr_red_assoc PF09655.10 ORY38335.1 - 0.057 14.1 4.6 0.35 11.5 0.0 3.5 3 0 0 3 3 3 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) TIR_2 PF13676.6 ORY38336.1 - 3.4e-07 30.9 0.0 6.5e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 TIR domain NB-ARC PF00931.22 ORY38336.1 - 0.00098 18.4 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 ORY38336.1 - 0.0038 17.6 0.0 0.011 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY38336.1 - 0.015 15.6 0.0 0.049 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ORY38336.1 - 0.037 14.0 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain TIR PF01582.20 ORY38336.1 - 0.048 13.4 0.1 0.12 12.2 0.1 1.6 1 1 0 1 1 1 0 TIR domain AAA PF00004.29 ORY38336.1 - 0.071 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_fla_DE PF04659.13 ORY38336.1 - 0.077 12.9 0.1 4.8 7.1 0.0 2.6 2 0 0 2 2 2 0 Archaeal flagella protein AAA_25 PF13481.6 ORY38336.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ORY38336.1 - 0.18 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TPR_12 PF13424.6 ORY38337.1 - 2.7e-51 171.7 23.6 3.3e-15 56.1 1.2 3.9 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 ORY38337.1 - 7.1e-39 130.6 0.5 3.8e-08 32.9 0.0 5.1 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 ORY38337.1 - 9.8e-24 81.5 10.8 1.5e-05 24.8 0.1 4.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORY38337.1 - 1.2e-22 78.1 15.5 1.6e-05 24.8 0.4 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 ORY38337.1 - 6.4e-22 76.4 13.4 1.8e-05 24.4 0.2 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 ORY38337.1 - 1.4e-15 56.7 0.1 0.076 13.9 0.0 4.7 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 ORY38337.1 - 2.9e-13 48.8 8.4 0.0077 16.2 0.1 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY38337.1 - 4.5e-12 46.0 8.4 2.1e-07 30.7 0.8 2.1 1 1 1 2 2 2 2 MalT-like TPR region Fis1_TPR_C PF14853.6 ORY38337.1 - 1e-10 41.5 9.7 0.0015 18.5 0.2 4.6 5 0 0 5 5 5 3 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 ORY38337.1 - 1.3e-10 41.8 0.2 0.19 12.4 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY38337.1 - 1.2e-09 38.5 4.5 0.00075 20.0 0.7 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 ORY38337.1 - 1.4e-08 34.0 4.2 0.076 12.5 0.1 4.4 4 0 0 4 4 4 3 SHNi-TPR TPR_6 PF13174.6 ORY38337.1 - 2.2e-07 31.1 9.4 0.64 10.8 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY38337.1 - 3.1e-07 30.3 2.1 1.4 9.4 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY38337.1 - 5.8e-07 29.6 4.9 0.076 13.3 0.3 3.8 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 ORY38337.1 - 1e-05 25.5 4.4 1.5 8.9 0.0 3.8 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain Toxin_13 PF07822.11 ORY38337.1 - 4.5e-05 23.5 0.3 0.72 10.0 0.0 3.3 3 0 0 3 3 3 2 Neurotoxin B-IV-like protein TPR_4 PF07721.14 ORY38337.1 - 0.0002 21.7 0.0 26 5.8 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat S_4TM PF18159.1 ORY38337.1 - 0.00094 18.6 0.3 3 7.1 0.0 3.0 1 1 2 3 3 3 1 SMODS-associating 4TM effector domain PPR PF01535.20 ORY38337.1 - 0.0016 18.6 0.1 36 4.9 0.0 4.3 4 0 0 4 4 4 0 PPR repeat T3SchapCesA PF11439.8 ORY38337.1 - 0.0019 18.3 0.4 10 6.4 0.1 3.6 3 1 0 3 3 3 0 Type III secretion system filament chaperone CesA Peptidase_U49 PF10463.9 ORY38337.1 - 0.0019 18.0 0.0 35 4.1 0.0 4.0 3 1 1 4 4 4 0 Peptidase U49 GAT PF03127.14 ORY38337.1 - 0.01 16.1 0.8 31 4.9 0.1 3.5 3 0 0 3 3 3 0 GAT domain FYRN PF05964.14 ORY38337.1 - 0.012 15.4 0.0 17 5.3 0.0 3.8 4 0 0 4 4 4 0 F/Y-rich N-terminus SPO22 PF08631.10 ORY38337.1 - 0.017 14.7 2.5 0.26 10.7 0.4 2.2 1 1 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like AP2 PF00847.20 ORY38337.1 - 0.019 15.2 3.9 38 4.6 0.0 4.2 4 0 0 4 4 4 0 AP2 domain TPR_3 PF07720.12 ORY38337.1 - 0.021 14.8 6.8 0.55 10.3 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 ORY38337.1 - 0.037 13.8 4.4 8 6.1 1.6 3.3 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain RPN7 PF10602.9 ORY38337.1 - 0.039 13.7 2.5 28 4.3 0.1 3.2 1 1 2 3 3 3 0 26S proteasome subunit RPN7 FliT PF05400.13 ORY38337.1 - 0.042 14.7 0.2 5.5 7.9 0.0 3.0 2 2 2 4 4 2 0 Flagellar protein FliT Baculo_PP31 PF05311.11 ORY38337.1 - 0.059 12.9 0.1 8.5 5.8 0.0 3.2 1 1 2 3 3 3 0 Baculovirus 33KDa late protein (PP31) KNTase_C PF07827.11 ORY38337.1 - 0.067 13.0 0.0 35 4.2 0.0 3.4 1 1 2 3 3 3 0 KNTase C-terminal domain TPR_9 PF13371.6 ORY38337.1 - 0.075 13.2 0.0 5 7.3 0.0 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat NDUF_C2 PF06374.11 ORY38337.1 - 0.086 13.0 0.1 29 4.9 0.0 2.9 1 1 2 3 3 3 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) YqjK PF13997.6 ORY38337.1 - 0.11 12.8 0.0 15 5.9 0.0 3.5 2 1 2 4 4 4 0 YqjK-like protein Cytochrom_B562 PF07361.11 ORY38337.1 - 0.11 13.2 2.1 43 4.9 0.1 3.6 4 0 0 4 4 4 0 Cytochrome b562 TPR_11 PF13414.6 ORY38337.1 - 0.12 12.0 14.5 3.1 7.6 0.2 4.5 4 0 0 4 4 4 0 TPR repeat GEN1_C PF18380.1 ORY38337.1 - 1 10.3 2.3 79 4.2 0.1 3.8 4 0 0 4 4 4 0 Holliday junction resolvase Gen1 C-terminal domain DUF1657 PF07870.11 ORY38337.1 - 1 9.3 8.2 7.1 6.6 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1657) Coat_F PF07875.12 ORY38337.1 - 2.5 8.4 4.6 75 3.7 0.0 3.6 4 0 0 4 4 3 0 Coat F domain Myb_DNA-bind_4 PF13837.6 ORY38339.1 - 0.018 15.4 0.1 0.062 13.7 0.1 1.9 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF3138 PF11336.8 ORY38339.1 - 0.15 10.6 1.0 0.21 10.2 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Orthopox_F7 PF05813.12 ORY38340.1 - 0.094 12.8 0.0 0.1 12.7 0.0 1.0 1 0 0 1 1 1 0 Orthopoxvirus F7 protein Ubiq-assoc PF09145.10 ORY38341.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-associated DUF5581 PF17744.1 ORY38342.1 - 0.3 10.4 0.4 13 5.1 0.1 3.4 5 0 0 5 5 5 0 Family of unknown function (DUF5581) Zn_clus PF00172.18 ORY38343.1 - 7.9e-07 29.1 7.4 1.5e-06 28.2 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EspF PF04806.12 ORY38345.1 - 0.078 13.4 0.1 3 8.3 0.1 2.7 2 0 0 2 2 2 0 EspF protein repeat LIM PF00412.22 ORY38346.1 - 3.8e-31 107.1 26.5 6.8e-11 42.2 5.5 3.2 3 0 0 3 3 3 3 LIM domain zf-RRN7 PF11781.8 ORY38346.1 - 0.29 10.9 0.1 0.29 10.9 0.1 5.0 5 0 0 5 5 5 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Mut7-C PF01927.16 ORY38346.1 - 4.6 7.4 15.0 0.34 11.0 0.5 3.0 2 2 1 3 3 3 0 Mut7-C RNAse domain WD40 PF00400.32 ORY38347.1 - 2.6e-42 142.0 13.7 2e-07 31.6 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY38347.1 - 3.8e-11 43.1 1.8 0.36 11.2 0.0 5.7 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY38347.1 - 3.7e-09 36.3 0.6 3.1e-05 23.5 0.1 2.1 1 1 1 2 2 2 2 WD40-like domain Nup160 PF11715.8 ORY38347.1 - 1e-06 27.7 5.6 0.99 8.0 0.0 5.1 2 2 4 6 6 6 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 ORY38347.1 - 1.4e-05 25.0 1.8 0.86 9.7 0.1 3.8 3 2 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region DUF5046 PF16465.5 ORY38347.1 - 0.00013 21.5 0.1 0.15 11.5 0.0 3.4 1 1 2 4 4 4 1 Domain of unknown function (DUF5046) PALB2_WD40 PF16756.5 ORY38347.1 - 0.00032 19.7 5.5 1.6 7.6 0.0 5.0 1 1 4 6 6 6 2 Partner and localizer of BRCA2 WD40 domain Arylsulfotran_2 PF14269.6 ORY38347.1 - 0.0011 18.5 0.3 0.88 8.9 0.1 3.0 2 1 1 3 3 3 1 Arylsulfotransferase (ASST) DUF1258 PF06869.12 ORY38347.1 - 0.0017 17.9 0.1 0.2 11.1 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1258) PQQ_2 PF13360.6 ORY38347.1 - 0.0018 17.9 1.2 0.061 12.9 0.5 2.6 1 1 2 3 3 3 1 PQQ-like domain DUF1513 PF07433.11 ORY38347.1 - 0.015 14.4 0.0 4.2 6.3 0.0 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF1513) TssD PF17642.1 ORY38347.1 - 0.035 13.9 0.0 17 5.2 0.0 3.3 2 1 1 3 3 3 0 Hemolysin coregulated protein Hcp (TssD) BRK PF07533.16 ORY38347.1 - 0.11 12.2 0.0 38 4.0 0.0 3.6 3 0 0 3 3 3 0 BRK domain Acyltransferase PF01553.21 ORY38348.1 - 5e-11 42.4 0.0 5.6e-10 39.0 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase POP1 PF06978.11 ORY38349.1 - 6.1e-37 127.6 16.5 3e-18 66.6 7.0 2.4 1 1 1 2 2 2 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 ORY38349.1 - 1.1e-24 86.6 0.0 2.6e-24 85.4 0.0 1.7 1 0 0 1 1 1 1 POPLD (NUC188) domain GCV_T PF01571.21 ORY38349.1 - 0.00045 19.7 0.0 0.0015 17.9 0.0 1.8 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain Pex16 PF08610.10 ORY38350.1 - 1.4e-82 277.5 0.0 1.5e-82 277.4 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Fe_dep_repress PF01325.19 ORY38350.1 - 0.062 13.5 0.2 0.93 9.7 0.0 2.3 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain Hist_deacetyl PF00850.19 ORY38351.1 - 2e-84 283.7 0.1 3e-84 283.1 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DnaJ PF00226.31 ORY38352.1 - 9.6e-20 70.5 0.2 2.7e-19 69.0 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain DUF3502 PF12010.8 ORY38352.1 - 0.0057 17.3 1.9 2.4 8.8 0.5 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF3502) DEAD_2 PF06733.15 ORY38353.1 - 2.1e-54 183.8 0.1 3.5e-54 183.1 0.1 1.4 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 ORY38353.1 - 1.1e-48 165.5 2.4 3.9e-43 147.4 0.5 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 ORY38353.1 - 6.4e-44 150.1 0.0 1.7e-43 148.8 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 ORY38353.1 - 7.1e-05 22.9 0.0 0.0074 16.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 ORY38353.1 - 0.00011 21.0 0.0 0.00058 18.7 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 ORY38353.1 - 0.015 15.6 0.9 0.7 10.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain DEAD PF00270.29 ORY38353.1 - 0.018 14.8 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_11 PF13086.6 ORY38353.1 - 0.021 14.6 1.4 0.038 13.8 0.0 2.0 3 0 0 3 3 3 0 AAA domain DUF2075 PF09848.9 ORY38353.1 - 0.059 12.6 0.0 2.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MDM10 PF12519.8 ORY38354.1 - 8e-32 110.7 9.3 7.8e-28 97.6 5.5 2.9 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 ORY38354.1 - 4.9e-07 29.5 0.3 6.6e-07 29.1 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic porin Ribosomal_S25 PF03297.15 ORY38355.1 - 4.9e-37 126.2 0.2 5.4e-37 126.0 0.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.7 ORY38355.1 - 0.015 15.1 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_CodY PF08222.11 ORY38355.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 CodY helix-turn-helix domain Pkinase PF00069.25 ORY38356.1 - 2.7e-65 220.4 0.1 9.4e-42 143.2 0.1 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY38356.1 - 2.3e-33 115.6 0.3 4.9e-25 88.3 0.2 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY38356.1 - 3.4e-05 23.3 1.2 0.003 16.9 0.0 2.9 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.14 ORY38356.1 - 0.00023 20.6 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY38356.1 - 0.00038 19.5 0.1 0.0006 18.9 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 ORY38356.1 - 0.00042 19.2 0.0 0.00054 18.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY38356.1 - 0.002 18.1 0.2 0.0085 16.0 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORY38356.1 - 0.011 15.4 0.3 0.059 13.0 0.0 2.0 1 1 1 2 2 2 0 RIO1 family Ank PF00023.30 ORY38358.1 - 1.6e-10 40.9 0.1 0.0048 17.3 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 ORY38358.1 - 9e-10 38.0 0.1 0.0072 16.7 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 ORY38358.1 - 1.1e-09 38.7 0.1 0.00086 19.9 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY38358.1 - 4.2e-07 30.1 0.0 0.0076 16.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY38358.1 - 8.9e-07 29.3 0.1 0.011 16.3 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Aa_trans PF01490.18 ORY38359.1 - 6.2e-40 137.2 23.7 7e-39 133.7 23.7 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein BAR_2 PF10455.9 ORY38361.1 - 5.8e-44 150.4 2.0 6.2e-43 147.0 2.0 1.9 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 ORY38361.1 - 5.9e-17 62.1 1.4 2.1e-16 60.3 1.4 1.7 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 ORY38361.1 - 3.3e-09 36.8 0.5 7.4e-09 35.7 0.1 1.6 2 0 0 2 2 2 1 BAR domain of APPL family Arfaptin PF06456.13 ORY38361.1 - 1.1e-05 25.1 0.1 2.4e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Arfaptin-like domain TMV_coat PF00721.21 ORY38361.1 - 0.0098 15.7 1.3 0.14 12.0 0.1 2.6 2 1 0 2 2 2 1 Virus coat protein (TMV like) Clusterin PF01093.17 ORY38361.1 - 0.03 13.4 0.3 0.14 11.2 0.0 1.9 1 1 0 2 2 2 0 Clusterin FokI_C PF02980.16 ORY38361.1 - 0.03 14.3 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease FokI, catalytic domain HBM PF16591.5 ORY38361.1 - 0.24 10.8 4.5 0.61 9.5 0.1 2.6 2 1 0 2 2 2 0 Helical bimodular sensor domain T3SS_needle_E PF08988.10 ORY38361.1 - 0.5 10.6 2.4 1 9.6 0.2 2.5 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle WD40 PF00400.32 ORY38364.1 - 1.9e-06 28.5 0.0 0.4 11.6 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY38364.1 - 0.00068 19.9 0.0 0.77 10.1 0.0 3.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 ORY38364.1 - 0.0007 19.5 0.5 1.8 8.6 0.0 3.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Lactonase PF10282.9 ORY38364.1 - 0.0049 16.2 0.0 0.015 14.5 0.0 1.7 1 1 1 2 2 2 1 Lactonase, 7-bladed beta-propeller SGL PF08450.12 ORY38364.1 - 0.035 13.7 0.2 0.54 9.8 0.0 2.7 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region UPF0180 PF03698.13 ORY38364.1 - 0.057 13.6 0.2 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) Cytochrom_D1 PF02239.16 ORY38364.1 - 0.068 11.7 0.0 0.22 10.0 0.0 1.8 2 1 0 2 2 2 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 ORY38364.1 - 0.12 12.9 0.4 6.8 7.3 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain TPR_14 PF13428.6 ORY38365.1 - 0.00031 21.3 0.0 0.31 12.0 0.0 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat LSM PF01423.22 ORY38366.1 - 3.6e-10 39.4 0.1 4.1e-10 39.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORY38366.1 - 5.2e-05 23.3 0.0 6.5e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Cyclin_N PF00134.23 ORY38367.1 - 1.4e-37 128.3 0.0 3.2e-37 127.1 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORY38367.1 - 6e-19 68.3 0.4 1e-17 64.3 0.0 2.8 2 1 0 2 2 2 1 Cyclin, C-terminal domain Peptidase_S64 PF08192.11 ORY38367.1 - 2.1 6.8 14.6 0.02 13.4 2.7 2.0 2 0 0 2 2 2 0 Peptidase family S64 CtsR_C PF17727.1 ORY38368.1 - 0.21 11.7 0.0 0.42 10.8 0.0 1.4 1 0 0 1 1 1 0 CtsR C-terminal dimerization domain SET PF00856.28 ORY38369.1 - 5.7e-10 39.8 0.0 3.8e-09 37.2 0.0 2.1 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 ORY38369.1 - 7.3e-08 32.4 9.3 7.3e-08 32.4 9.3 2.3 2 0 0 2 2 2 1 MYND finger Rad4 PF03835.15 ORY38370.1 - 8.2e-11 41.8 1.0 1.5e-10 41.0 1.0 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 ORY38370.1 - 3e-08 34.1 1.7 3.8e-08 33.7 0.4 1.9 2 0 0 2 2 2 1 Transglutaminase-like superfamily PAW PF04721.17 ORY38370.1 - 0.0027 17.5 0.0 0.0061 16.4 0.0 1.6 1 0 0 1 1 1 1 PNGase C-terminal domain, mannose-binding module PAW DUF874 PF05917.11 ORY38370.1 - 0.039 13.0 1.3 0.056 12.5 1.3 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) F-box-like PF12937.7 ORY38371.1 - 0.0016 18.3 1.8 0.0037 17.1 0.2 2.5 2 1 0 2 2 2 1 F-box-like F-box PF00646.33 ORY38371.1 - 0.029 14.3 0.3 14 5.7 0.1 3.1 2 0 0 2 2 2 0 F-box domain Efg1 PF10153.9 ORY38372.1 - 4.9e-28 97.8 13.1 4.9e-28 97.8 13.1 2.7 2 1 0 2 2 2 1 rRNA-processing protein Efg1 SMC_ScpB PF04079.16 ORY38372.1 - 0.01 15.5 3.3 0.012 15.2 2.1 1.7 2 0 0 2 2 2 0 Segregation and condensation complex subunit ScpB AlaDh_PNT_N PF05222.15 ORY38372.1 - 0.04 14.2 2.6 0.33 11.2 0.4 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, N-terminal domain MCR_C PF04609.12 ORY38372.1 - 0.26 10.3 2.6 0.38 9.8 0.2 2.1 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein C NOA36 PF06524.12 ORY38372.1 - 0.41 9.9 11.1 0.74 9.1 11.1 1.4 1 0 0 1 1 1 0 NOA36 protein FlxA PF14282.6 ORY38372.1 - 0.98 9.4 26.1 0.68 10.0 3.4 3.5 2 1 1 3 3 3 0 FlxA-like protein DUF2813 PF11398.8 ORY38372.1 - 3.5 6.8 14.1 0.042 13.1 4.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) FF PF01846.19 ORY38373.1 - 1.3e-36 124.5 24.5 7.8e-13 48.4 0.4 5.6 5 0 0 5 5 5 5 FF domain WW PF00397.26 ORY38373.1 - 1.3e-13 50.8 4.0 1.1e-08 35.0 1.7 2.8 2 0 0 2 2 2 2 WW domain Kelch_4 PF13418.6 ORY38373.1 - 0.0025 17.8 1.2 5.4 7.1 0.0 4.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY38373.1 - 0.025 14.8 0.4 17 5.8 0.0 3.6 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.6 ORY38373.1 - 0.16 12.3 16.9 0.56 10.6 0.1 6.0 6 0 0 6 6 6 0 Galactose oxidase, central domain RhoGAP-FF1 PF16512.5 ORY38373.1 - 1.2 9.9 5.0 11 6.7 0.1 3.5 2 1 1 3 3 3 0 p190-A and -B Rho GAPs FF domain zf-RanBP PF00641.18 ORY38374.1 - 4.4e-07 29.1 1.1 7.5e-07 28.4 1.1 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others DUF2072 PF09845.9 ORY38374.1 - 9 6.6 9.2 0.54 10.5 0.2 2.9 3 0 0 3 3 3 0 Zn-ribbon containing protein Exo_endo_phos PF03372.23 ORY38375.1 - 1.7e-07 31.0 0.4 2.7e-07 30.4 0.4 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family U-box PF04564.15 ORY38376.1 - 4.8e-11 42.7 0.0 7.9e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 ORY38376.1 - 9.1e-05 22.5 0.3 0.00019 21.5 0.0 1.6 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 ORY38376.1 - 0.00024 21.1 0.0 0.0018 18.3 0.0 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.8 ORY38376.1 - 0.00047 19.9 0.0 0.00085 19.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 ORY38376.1 - 0.0082 16.3 0.0 0.17 12.1 0.0 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING VASt PF16016.5 ORY38377.1 - 2.8e-17 63.5 0.0 8e-17 62.1 0.0 1.8 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain Asp PF00026.23 ORY38379.1 - 2.2e-20 73.3 11.6 2.9e-20 72.9 11.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 ORY38379.1 - 1.3e-08 34.8 0.0 2.2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 ORY38379.1 - 0.00015 22.3 0.7 0.0016 19.1 0.1 2.9 2 1 1 3 3 3 1 Aspartyl protease DUF4992 PF16383.5 ORY38379.1 - 0.049 13.2 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function gag-asp_proteas PF13975.6 ORY38379.1 - 0.058 14.0 0.2 0.66 10.6 0.0 2.7 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease FAM194 PF14977.6 ORY38380.1 - 3.7 6.8 15.0 0.26 10.6 3.8 3.5 3 0 0 3 3 3 0 FAM194 protein Filament PF00038.21 ORY38381.1 - 0.00055 19.6 24.2 0.00055 19.6 24.2 9.6 1 1 7 10 10 10 6 Intermediate filament protein DNA_pol_phi PF04931.13 ORY38382.1 - 0.33 9.0 11.8 0.68 8.0 11.8 1.4 1 0 0 1 1 1 0 DNA polymerase phi Cytomega_TRL10 PF06084.11 ORY38382.1 - 1.5 8.9 4.8 5.4 7.0 4.8 2.0 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Pribosyltran_N PF13793.6 ORY38383.1 - 3.8e-40 136.5 2.7 1.5e-39 134.5 0.2 2.3 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 ORY38383.1 - 3.1e-33 115.3 4.6 1.6e-28 100.0 2.7 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 ORY38383.1 - 9.9e-10 38.2 0.3 1.9e-09 37.2 0.3 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PTPA PF03095.15 ORY38384.1 - 1.2e-115 386.1 0.0 1.5e-115 385.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Na_sulph_symp PF00939.19 ORY38386.1 - 1.6e-34 119.8 32.2 2.4e-34 119.2 32.2 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region SPX PF03105.19 ORY38386.1 - 2e-32 113.6 2.5 2.6e-32 113.2 2.5 1.2 1 0 0 1 1 1 1 SPX domain CitMHS PF03600.16 ORY38386.1 - 2.7e-27 95.8 57.8 1.8e-24 86.5 32.7 2.2 1 1 1 2 2 2 2 Citrate transporter LSM PF01423.22 ORY38387.1 - 3.3e-16 58.7 0.0 4.3e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORY38387.1 - 0.017 15.3 0.0 0.023 14.8 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain LSM14 PF12701.7 ORY38387.1 - 0.067 13.3 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Scd6-like Sm domain RhlB PF12300.8 ORY38387.1 - 0.15 12.2 9.0 0.17 12.0 9.0 1.2 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB Fer2_3 PF13085.6 ORY38388.1 - 2.1e-31 108.2 0.0 3.2e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 ORY38388.1 - 1.8e-09 38.0 5.0 1.8e-09 38.0 5.0 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 ORY38388.1 - 6.8e-07 29.6 8.0 6.8e-07 29.6 8.0 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 ORY38388.1 - 1.3e-06 28.4 3.0 1.3e-06 28.4 3.0 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 ORY38388.1 - 0.0053 16.7 2.9 0.0092 15.9 0.4 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 ORY38388.1 - 0.17 12.1 12.4 0.043 14.0 6.6 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 ORY38388.1 - 0.45 11.5 8.1 3 8.8 1.2 3.0 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain CutC PF03932.14 ORY38389.1 - 1.9e-70 236.5 0.6 2.2e-70 236.3 0.6 1.0 1 0 0 1 1 1 1 CutC family ACT_5 PF13710.6 ORY38389.1 - 0.98 9.3 4.3 0.89 9.4 0.2 2.8 4 0 0 4 4 4 0 ACT domain Ribosomal_L24e PF01246.20 ORY38390.1 - 1.3e-27 95.8 0.1 1.3e-27 95.8 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e FANC_SAP PF18081.1 ORY38390.1 - 0.32 11.2 3.9 0.29 11.3 1.7 2.0 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain Spem1 PF15670.5 ORY38390.1 - 0.44 10.1 3.9 0.49 9.9 3.9 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 Glyco_hydro_18 PF00704.28 ORY38391.1 - 7.8e-06 25.8 0.0 0.064 13.0 0.0 2.3 2 1 0 2 2 2 2 Glycosyl hydrolases family 18 ThrE PF06738.12 ORY38392.1 - 2.8e-52 177.5 24.3 3.3e-48 164.2 6.3 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORY38392.1 - 1.1e-08 35.3 11.0 1.1e-08 35.3 11.0 2.9 3 0 0 3 3 3 1 Threonine/Serine exporter, ThrE DUF4191 PF13829.6 ORY38392.1 - 1.3 8.3 6.2 3.5 6.9 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF4231 PF14015.6 ORY38392.1 - 2.2 8.8 3.8 2.4 8.7 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Ras PF00071.22 ORY38393.1 - 5.8e-30 104.0 0.1 7.3e-30 103.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY38393.1 - 3e-20 72.6 0.1 4.4e-20 72.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY38393.1 - 1e-09 38.1 0.0 1.4e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY38393.1 - 2.3e-05 23.9 0.0 3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 ORY38393.1 - 9.3e-05 21.7 0.3 0.024 13.8 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 ORY38393.1 - 0.0094 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORY38393.1 - 0.035 14.2 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF420 PF04238.12 ORY38393.1 - 0.044 14.1 0.0 0.067 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF420) TniB PF05621.11 ORY38393.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Glyco_hydro_18 PF00704.28 ORY38394.1 - 4e-06 26.8 0.0 0.038 13.7 0.0 2.3 2 1 0 2 2 2 2 Glycosyl hydrolases family 18 DUF4455 PF14643.6 ORY38395.1 - 0.0007 18.4 0.4 0.0044 15.7 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4455) UPF0139 PF03669.13 ORY38396.1 - 0.072 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0139) PASTA PF03793.19 ORY38399.1 - 0.19 11.6 1.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 PASTA domain ubiquitin PF00240.23 ORY38401.1 - 3.4e-18 65.2 0.0 6.7e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY38401.1 - 6e-09 35.6 0.1 1.2e-08 34.6 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-RING_2 PF13639.6 ORY38401.1 - 8.5e-05 22.8 10.6 8.5e-05 22.8 10.6 2.6 2 1 1 3 3 3 1 Ring finger domain C1_1 PF00130.22 ORY38401.1 - 0.014 15.3 6.5 0.014 15.3 6.5 2.2 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TBK1_ULD PF18396.1 ORY38401.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 ORY38401.1 - 0.071 13.5 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Zn-ribbon_8 PF09723.10 ORY38401.1 - 0.093 12.9 11.9 1.7 8.8 7.2 2.8 2 0 0 2 2 2 0 Zinc ribbon domain Ubiquitin_2 PF14560.6 ORY38401.1 - 0.13 12.7 0.0 0.68 10.4 0.0 2.1 1 1 0 1 1 1 0 Ubiquitin-like domain zf-RING_11 PF17123.5 ORY38401.1 - 0.19 11.5 3.1 0.57 10.0 3.1 1.9 1 0 0 1 1 1 0 RING-like zinc finger Prok-RING_1 PF14446.6 ORY38401.1 - 0.22 11.5 14.4 0.15 12.0 7.5 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 PHD PF00628.29 ORY38401.1 - 1.8 8.5 15.5 0.36 10.7 11.0 2.2 2 0 0 2 2 2 0 PHD-finger zinc_ribbon_4 PF13717.6 ORY38401.1 - 2.3 8.2 7.2 0.62 10.0 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-C3HC4_2 PF13923.6 ORY38401.1 - 2.7 7.9 15.7 3.2 7.7 9.7 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY38401.1 - 5.7 7.3 13.4 2.5 8.5 9.4 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger domain FixQ PF05545.11 ORY38403.1 - 0.046 13.7 0.1 0.089 12.8 0.1 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ CMAS PF02353.20 ORY38406.1 - 6.5e-29 101.1 0.0 8.4e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 ORY38406.1 - 1.7e-11 44.7 0.0 4.1e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY38406.1 - 2.4e-10 40.5 0.0 3.8e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY38406.1 - 6.9e-10 39.4 0.0 1.5e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY38406.1 - 2.6e-09 37.1 0.0 4.4e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY38406.1 - 2e-08 34.9 0.0 3.8e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 ORY38406.1 - 3.7e-05 23.2 0.0 6.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 ORY38406.1 - 0.00011 21.8 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 ORY38406.1 - 0.00033 20.2 0.0 0.0006 19.3 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.20 ORY38406.1 - 0.0096 15.0 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase GidB PF02527.15 ORY38406.1 - 0.02 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DUF938 PF06080.12 ORY38406.1 - 0.021 14.6 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) tRNA_U5-meth_tr PF05958.11 ORY38406.1 - 0.022 13.8 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase PCMT PF01135.19 ORY38406.1 - 0.059 13.1 0.0 0.08 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 ORY38406.1 - 0.14 11.7 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Erf4 PF10256.9 ORY38407.1 - 7.8e-11 42.1 0.0 1.2e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family CHCH PF06747.13 ORY38408.1 - 0.005 16.9 6.0 0.005 16.9 6.0 2.0 2 1 0 2 2 2 1 CHCH domain Ndufs5 PF10200.9 ORY38408.1 - 0.4 11.0 3.9 0.95 9.8 3.9 1.6 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cytochrom_B561 PF03188.16 ORY38409.1 - 1.6e-09 38.0 11.3 4.3e-09 36.6 11.3 1.7 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.17 ORY38409.1 - 0.00067 19.9 0.0 0.0018 18.4 0.0 1.7 1 0 0 1 1 1 1 DOMON domain DUF4079 PF13301.6 ORY38409.1 - 0.031 14.4 11.4 0.14 12.3 11.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) DUF1461 PF07314.11 ORY38409.1 - 1.7 8.5 8.2 0.67 9.8 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1461) zf-AN1 PF01428.16 ORY38410.1 - 4.1e-09 36.4 9.2 5.9e-09 35.9 9.2 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger UPF1_Zn_bind PF09416.10 ORY38410.1 - 0.015 15.3 3.4 0.017 15.1 3.4 1.1 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) C5HCH PF17982.1 ORY38410.1 - 0.016 15.3 4.0 0.016 15.3 4.0 1.5 1 1 0 1 1 1 0 NSD Cys-His rich domain zf-C2H2_4 PF13894.6 ORY38410.1 - 5.2 8.2 9.3 3.1 8.9 4.3 2.4 2 1 0 2 2 2 0 C2H2-type zinc finger LRR_4 PF12799.7 ORY38411.1 - 0.0057 17.1 1.3 0.87 10.1 0.1 3.4 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY38411.1 - 0.0081 16.6 5.2 1.6 9.6 0.7 4.9 4 2 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.6 ORY38411.1 - 0.01 15.8 0.9 0.31 11.2 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeat F-box-like PF12937.7 ORY38411.1 - 0.071 13.0 0.3 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.7 ORY38412.1 - 1.5e-05 24.8 0.2 4.4e-05 23.3 0.2 1.9 1 0 0 1 1 1 1 F-box-like FANCI_S4 PF14678.6 ORY38412.1 - 0.054 12.6 0.2 0.17 11.0 0.4 1.7 2 0 0 2 2 2 0 FANCI solenoid 4 Mitofilin PF09731.9 ORY38412.1 - 0.8 8.5 4.9 1.2 7.9 4.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Muted PF14942.6 ORY38412.1 - 2.2 8.6 7.3 4.2 7.7 7.3 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein ubiquitin PF00240.23 ORY38413.1 - 7.5e-18 64.0 0.1 1.9e-17 62.8 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin family zf-RING_2 PF13639.6 ORY38413.1 - 0.00012 22.3 9.1 0.00012 22.3 9.1 2.7 2 0 0 2 2 2 1 Ring finger domain Rad60-SLD PF11976.8 ORY38413.1 - 0.0057 16.5 0.0 0.0094 15.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PHD PF00628.29 ORY38413.1 - 6.5 6.7 15.4 0.65 9.9 9.6 2.3 2 0 0 2 2 2 0 PHD-finger Cut8 PF08559.10 ORY38414.1 - 2.6e-31 109.1 0.1 2.6e-31 109.1 0.1 2.2 2 1 1 3 3 3 1 Cut8, nuclear proteasome tether protein MukF_M PF17192.4 ORY38414.1 - 0.07 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 MukF middle domain SOG2 PF10428.9 ORY38414.1 - 0.19 10.9 20.7 0.22 10.7 11.7 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein Nucleo_P87 PF07267.11 ORY38414.1 - 6 5.6 6.3 0.62 8.9 1.9 1.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 FSA_C PF10479.9 ORY38414.1 - 7.8 4.5 24.0 1.7 6.7 18.2 2.0 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus Il2rg PF15874.5 ORY38415.1 - 4.7e-22 78.0 0.0 5.6e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 Putative Interleukin 2 receptor, gamma chain WD40 PF00400.32 ORY38416.1 - 5.6e-09 36.5 4.4 0.004 18.0 0.0 4.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Pkinase PF00069.25 ORY38418.1 - 5.6e-65 219.3 0.0 7.2e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY38418.1 - 1.6e-27 96.4 0.0 2.2e-27 96.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY38418.1 - 3.2e-05 23.4 0.0 8.7e-05 22.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORY38418.1 - 0.00033 19.7 6.9 0.0018 17.3 6.9 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY38418.1 - 0.22 10.8 0.5 0.47 9.8 0.5 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY38418.1 - 5 5.8 5.1 1 8.0 0.1 1.9 2 0 0 2 2 2 0 Fungal protein kinase GST_N PF02798.20 ORY38421.1 - 0.13 12.6 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF4203 PF13886.6 ORY38422.1 - 3.1e-08 33.5 3.8 3.1e-08 33.5 3.8 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) YtxH PF12732.7 ORY38422.1 - 0.0093 16.5 0.1 5.2 7.7 0.0 2.2 2 0 0 2 2 2 2 YtxH-like protein TauE PF01925.19 ORY38422.1 - 0.017 14.8 4.9 0.022 14.4 4.9 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE DUF4203 PF13886.6 ORY38423.1 - 5.1e-21 75.3 17.1 6e-21 75.0 17.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) IalB PF06776.12 ORY38423.1 - 0.085 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Invasion associated locus B (IalB) protein Rhomboid PF01694.22 ORY38423.1 - 0.086 12.8 8.9 1.3 9.0 4.4 2.1 1 1 1 2 2 2 0 Rhomboid family BPD_transp_1 PF00528.22 ORY38423.1 - 1.6 8.4 8.8 7.9 6.2 6.0 2.5 2 1 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component GCP_N_terminal PF17681.1 ORY38424.1 - 3.2e-64 217.5 0.0 8.4e-64 216.1 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 ORY38424.1 - 1.7e-63 214.9 0.8 3.2e-63 214.1 0.2 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Coilin_N PF15862.5 ORY38424.1 - 0.0093 15.8 1.9 0.3 10.9 0.8 3.0 2 0 0 2 2 2 1 Coilin N-terminus Transposase_20 PF02371.16 ORY38424.1 - 2.7 8.4 6.1 1.4 9.3 0.6 2.6 2 0 0 2 2 2 0 Transposase IS116/IS110/IS902 family TFIIA PF03153.13 ORY38424.1 - 4.6 7.1 9.8 8.8 6.2 9.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Drc1-Sld2 PF11719.8 ORY38424.1 - 6.9 6.1 13.7 12 5.3 13.7 1.4 1 0 0 1 1 1 0 DNA replication and checkpoint protein Peptidase_M16_M PF16187.5 ORY38425.1 - 8.7e-96 320.5 1.0 1.2e-95 320.0 1.0 1.2 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 ORY38425.1 - 6.3e-41 140.4 0.1 2.7e-26 92.7 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ORY38425.1 - 3e-38 131.1 0.5 1.7e-37 128.7 0.2 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DNA_pol_A_exo1 PF01612.20 ORY38426.1 - 2.5e-12 46.8 0.0 3.9e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Chorismate_bind PF00425.18 ORY38428.1 - 4.9e-73 245.9 0.0 9.5e-73 244.9 0.0 1.5 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 ORY38428.1 - 1.7e-38 132.3 0.0 3.1e-38 131.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 ORY38428.1 - 1.7e-13 51.0 0.0 8.8e-13 48.7 0.0 2.3 1 1 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 ORY38428.1 - 7.5e-08 32.4 0.1 2.6e-07 30.6 0.1 1.8 1 1 0 1 1 1 1 Peptidase C26 Formyl_trans_C PF02911.18 ORY38428.1 - 0.074 13.3 0.1 0.86 9.9 0.0 2.3 2 0 0 2 2 2 0 Formyl transferase, C-terminal domain Nucleoside_tran PF01733.18 ORY38429.1 - 2.2e-15 56.8 2.0 2.2e-15 56.8 2.0 3.8 3 1 1 4 4 4 2 Nucleoside transporter MFS_1 PF07690.16 ORY38429.1 - 0.23 10.3 36.5 1.2 8.0 36.5 2.1 1 1 0 1 1 1 0 Major Facilitator Superfamily FAD_binding_1 PF00667.20 ORY38430.1 - 4.9e-33 114.6 0.0 7.2e-33 114.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORY38430.1 - 1.6e-29 103.0 0.0 8.5e-29 100.6 0.0 2.2 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 ORY38430.1 - 4.7e-13 49.7 0.0 1.1e-12 48.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 ORY38430.1 - 0.019 15.2 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin domain NAD_binding_6 PF08030.12 ORY38430.1 - 0.036 14.2 0.1 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 Ferric reductase NAD binding domain ODV-E18 PF10717.9 ORY38431.1 - 0.0083 16.0 1.0 0.013 15.4 1.0 1.3 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 DUF2207 PF09972.9 ORY38431.1 - 0.011 14.5 2.3 0.014 14.2 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Podoplanin PF05808.11 ORY38431.1 - 0.015 15.4 0.6 0.027 14.6 0.6 1.5 1 0 0 1 1 1 0 Podoplanin Phage_holin_3_6 PF07332.11 ORY38431.1 - 0.043 13.9 12.4 0.29 11.2 2.4 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Lipase_GDSL_2 PF13472.6 ORY38432.1 - 0.052 14.0 0.3 0.068 13.6 0.3 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.16 ORY38433.1 - 1e-30 106.9 67.3 2.4e-20 72.8 30.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2367 PF10164.9 ORY38435.1 - 0.15 12.5 4.2 3.2 8.3 0.7 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) DUF5092 PF17010.5 ORY38436.1 - 4.8e-38 130.6 1.7 2.6e-37 128.2 1.7 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF5092) Metallophos PF00149.28 ORY38437.1 - 8.6e-35 121.1 0.0 1.6e-34 120.2 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 ORY38437.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) Glyco_transf_6 PF03414.13 ORY38438.1 - 0.14 10.9 0.1 0.21 10.3 0.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 6 DUF2321 PF10083.9 ORY38438.1 - 0.18 11.4 3.4 0.4 10.3 0.2 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) DUF4094 PF13334.6 ORY38439.1 - 0.043 14.2 0.9 0.12 12.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) PPR_2 PF13041.6 ORY38439.1 - 0.073 13.3 0.0 27 5.0 0.0 3.6 4 0 0 4 4 4 0 PPR repeat family F-box PF00646.33 ORY38439.1 - 0.18 11.7 1.2 1.3 9.0 0.0 2.8 3 0 0 3 3 3 0 F-box domain Abhydrolase_1 PF00561.20 ORY38440.1 - 1.4e-32 113.4 0.0 1.7e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY38440.1 - 1.7e-09 38.7 0.2 2.3e-09 38.2 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY38440.1 - 5.1e-09 35.7 0.0 6.4e-08 32.2 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 ORY38440.1 - 0.0011 17.7 0.0 0.0016 17.2 0.0 1.2 1 0 0 1 1 1 1 Ndr family Peptidase_S28 PF05577.12 ORY38440.1 - 0.048 12.4 0.0 0.17 10.6 0.0 1.8 2 0 0 2 2 2 0 Serine carboxypeptidase S28 Sel1 PF08238.12 ORY38441.1 - 7.8e-29 99.5 23.6 0.046 14.4 0.0 11.9 12 0 0 12 12 12 8 Sel1 repeat SPO22 PF08631.10 ORY38441.1 - 0.00016 21.3 4.1 2.1 7.8 0.0 5.0 3 2 2 5 5 5 2 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.6 ORY38441.1 - 0.0024 18.1 0.4 6.3 7.2 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY38441.1 - 0.003 17.5 12.7 1.5 9.1 0.1 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY38441.1 - 0.013 16.2 0.3 8.4 7.5 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat ANTAR PF03861.14 ORY38441.1 - 0.17 11.8 0.1 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 ANTAR domain TPR_19 PF14559.6 ORY38441.1 - 0.54 10.8 4.1 4.7 7.8 0.1 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY38441.1 - 2.5 8.5 6.9 18 5.8 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY38441.1 - 8.4 6.2 9.0 6.6 6.5 0.2 4.7 4 2 0 4 4 4 0 TPR repeat Ank_2 PF12796.7 ORY38442.1 - 6.5e-24 84.3 2.1 2.6e-13 50.4 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY38442.1 - 9.6e-23 80.3 2.1 6.1e-12 45.8 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY38442.1 - 1e-22 79.5 6.4 1.2e-08 35.0 0.1 4.2 3 1 1 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 ORY38442.1 - 2.2e-20 70.6 2.4 1.4e-07 31.2 0.0 4.9 4 1 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 ORY38442.1 - 6e-20 71.0 3.3 3.2e-11 43.2 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) ATP-gua_PtransN PF02807.15 ORY38444.1 - 0.028 14.8 0.1 1 9.8 0.1 2.5 2 1 0 2 2 2 0 ATP:guanido phosphotransferase, N-terminal domain EF-hand_6 PF13405.6 ORY38445.1 - 1.4e-06 27.7 0.7 3.6e-06 26.5 0.4 1.8 2 1 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 ORY38445.1 - 0.0058 16.1 0.8 0.011 15.2 0.8 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 ORY38445.1 - 0.0087 16.5 0.2 0.016 15.7 0.0 1.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 ORY38445.1 - 0.0093 15.5 0.1 0.02 14.4 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 ORY38445.1 - 0.067 13.1 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 ORY38446.1 - 7.7e-12 44.1 4.7 2.7e-05 23.7 0.3 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 ORY38446.1 - 5.4e-08 31.8 4.5 0.00016 21.0 0.5 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 ORY38446.1 - 1.7e-07 31.6 3.3 0.00087 19.7 0.3 2.9 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 ORY38446.1 - 6.7e-06 25.4 5.4 0.00019 20.8 1.0 2.7 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 ORY38446.1 - 0.14 12.5 0.3 13 6.1 0.0 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 ORY38446.1 - 0.2 11.5 6.8 1.7 8.6 0.4 3.7 4 0 0 4 4 4 0 EF-hand domain pair Alpha_kinase PF02816.18 ORY38447.1 - 6.2e-18 65.6 1.3 6.2e-18 65.6 1.3 1.6 2 0 0 2 2 2 1 Alpha-kinase family HTH_21 PF13276.6 ORY38448.1 - 0.17 12.0 1.2 0.54 10.4 0.0 2.4 3 0 0 3 3 3 0 HTH-like domain Stc1 PF12898.7 ORY38448.1 - 0.76 10.4 5.9 0.66 10.6 1.7 2.7 2 0 0 2 2 2 0 Stc1 domain mRNA_cap_enzyme PF01331.19 ORY38450.1 - 0.0014 18.5 1.0 0.55 10.0 0.1 2.9 3 0 0 3 3 3 2 mRNA capping enzyme, catalytic domain NUC173 PF08161.12 ORY38450.1 - 0.032 13.9 5.0 8.8 5.9 0.1 3.4 3 0 0 3 3 3 0 NUC173 domain CEP63 PF17045.5 ORY38450.1 - 0.052 13.4 0.4 13 5.6 0.0 2.4 3 0 0 3 3 3 0 Centrosomal protein of 63 kDa Ribosomal_S15 PF00312.22 ORY38450.1 - 0.11 12.8 2.7 6.7 7.0 0.1 3.0 3 0 0 3 3 3 0 Ribosomal protein S15 RasGAP_C PF03836.15 ORY38450.1 - 0.18 12.0 0.4 76 3.4 0.0 3.0 2 1 0 3 3 3 0 RasGAP C-terminus DUF2400 PF09674.10 ORY38450.1 - 0.21 11.6 3.0 5.6 6.9 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2400) Arfaptin PF06456.13 ORY38450.1 - 0.76 9.3 2.5 48 3.4 0.0 3.2 1 1 1 3 3 3 0 Arfaptin-like domain Flavi_capsid PF01003.19 ORY38450.1 - 3.8 7.3 6.6 18 5.2 0.1 3.0 3 0 0 3 3 3 0 Flavivirus capsid protein C DUF4094 PF13334.6 ORY38451.1 - 0.032 14.7 0.2 0.075 13.5 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) PPR_2 PF13041.6 ORY38451.1 - 0.036 14.3 0.0 12 6.2 0.0 3.1 3 0 0 3 3 3 0 PPR repeat family Sigma70_r4_2 PF08281.12 ORY38451.1 - 0.08 12.6 0.6 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 ATG16 PF08614.11 ORY38451.1 - 2.5 8.3 6.9 0.36 11.0 0.7 2.0 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SLED PF12140.8 ORY38452.1 - 0.019 15.5 0.0 9.4 6.8 0.0 2.3 1 1 1 2 2 2 0 SLED domain DUF3274 PF11678.8 ORY38452.1 - 0.078 12.2 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3274) GREB1 PF15782.5 ORY38453.1 - 3.1 4.8 12.3 3.7 4.6 12.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIA PF03153.13 ORY38453.1 - 6.1 6.7 12.8 7.7 6.4 12.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Abhydrolase_1 PF00561.20 ORY38454.1 - 1.8e-32 113.0 0.0 2.3e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY38454.1 - 3.6e-09 37.6 0.1 4.9e-09 37.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY38454.1 - 5.2e-09 35.7 0.0 6.5e-08 32.1 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 ORY38454.1 - 0.0011 17.8 0.0 0.0016 17.2 0.0 1.2 1 0 0 1 1 1 1 Ndr family Peptidase_S28 PF05577.12 ORY38454.1 - 0.048 12.4 0.0 0.17 10.6 0.0 1.8 2 0 0 2 2 2 0 Serine carboxypeptidase S28 Sel1 PF08238.12 ORY38455.1 - 4.4e-32 109.8 30.9 0.065 13.9 0.0 14.5 15 0 0 15 15 15 10 Sel1 repeat Ank_2 PF12796.7 ORY38455.1 - 2.8e-09 37.4 0.1 1.2e-08 35.4 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY38455.1 - 3.1e-07 30.5 0.7 0.001 19.4 0.3 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 ORY38455.1 - 5.3e-07 29.5 0.4 0.00041 20.6 0.1 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 ORY38455.1 - 5.4e-07 29.8 0.3 3.3e-05 24.1 0.2 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY38455.1 - 1e-05 26.0 0.1 3.9e-05 24.1 0.0 2.1 2 0 0 2 2 1 1 Ankyrin repeats (many copies) SPO22 PF08631.10 ORY38455.1 - 4.7e-05 23.0 8.0 3.9 6.9 0.0 6.4 4 2 3 7 7 7 2 Meiosis protein SPO22/ZIP4 like TPR_14 PF13428.6 ORY38455.1 - 0.0082 16.9 0.4 13 6.9 0.1 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY38455.1 - 0.0098 16.2 0.5 10 6.5 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY38455.1 - 0.022 14.8 14.6 2.1 8.7 0.1 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat ANTAR PF03861.14 ORY38455.1 - 0.11 12.3 0.1 1.9 8.4 0.0 3.2 4 0 0 4 4 4 0 ANTAR domain TPR_19 PF14559.6 ORY38455.1 - 0.29 11.7 4.2 6.8 7.3 0.1 4.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY38455.1 - 3.1 8.2 6.6 26 5.4 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat UQ_con PF00179.26 ORY38457.1 - 0.0084 15.8 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Orbi_VP6 PF01516.16 ORY38457.1 - 0.2 11.2 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 SPATA1_C PF15743.5 ORY38459.1 - 0.0024 17.9 3.2 0.0036 17.4 3.2 1.2 1 0 0 1 1 1 1 Spermatogenesis-associated C-terminus DUF3015 PF11220.8 ORY38459.1 - 0.02 14.8 1.3 0.044 13.6 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) FlaC_arch PF05377.11 ORY38459.1 - 0.68 10.4 3.0 2.7 8.5 0.1 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4355 PF14265.6 ORY38459.1 - 0.77 10.0 8.9 1.4 9.1 8.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) TMPIT PF07851.13 ORY38459.1 - 5.2 6.2 5.5 7.9 5.6 5.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein Baculo_PEP_C PF04513.12 ORY38460.1 - 0.00089 19.3 3.0 0.00089 19.3 3.0 2.5 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus HSBP1 PF06825.12 ORY38460.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 DUF3450 PF11932.8 ORY38461.1 - 0.00036 19.9 1.5 0.00044 19.6 1.2 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) Nsp1_C PF05064.13 ORY38461.1 - 0.001 18.8 1.2 0.0011 18.7 1.2 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region ZapB PF06005.12 ORY38461.1 - 0.0018 18.7 5.1 0.0025 18.2 5.1 1.3 1 1 0 1 1 1 1 Cell division protein ZapB BLOC1_2 PF10046.9 ORY38461.1 - 0.0021 18.3 1.1 0.0027 17.9 1.1 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 ORY38461.1 - 0.0031 17.4 0.9 0.0035 17.2 0.9 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 BST2 PF16716.5 ORY38461.1 - 0.0038 17.8 2.3 0.0049 17.4 2.3 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 GAS PF13851.6 ORY38461.1 - 0.0039 16.6 2.9 0.0044 16.4 2.9 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 ORY38461.1 - 0.017 15.1 2.0 0.017 15.1 2.0 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Cluap1 PF10234.9 ORY38461.1 - 0.018 14.4 1.5 0.019 14.4 1.5 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Tropomyosin_1 PF12718.7 ORY38461.1 - 0.024 14.8 2.5 0.036 14.2 2.5 1.4 1 1 0 1 1 1 0 Tropomyosin like YabA PF06156.13 ORY38461.1 - 0.026 15.1 1.3 0.031 14.9 1.3 1.2 1 0 0 1 1 1 0 Initiation control protein YabA HlyD_D23 PF16576.5 ORY38461.1 - 0.028 13.6 1.0 0.03 13.5 1.0 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Herpes_UL6 PF01763.16 ORY38461.1 - 0.028 12.9 1.7 0.029 12.9 1.7 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like BSP PF04450.12 ORY38461.1 - 0.034 14.0 0.0 0.053 13.3 0.0 1.3 1 1 0 1 1 1 0 Peptidase of plants and bacteria Rab_bind PF16704.5 ORY38461.1 - 0.035 14.1 0.3 2.8 8.1 0.1 2.3 1 1 1 2 2 2 0 Rab binding domain DUF948 PF06103.11 ORY38461.1 - 0.041 14.1 0.5 0.058 13.7 0.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 ORY38461.1 - 0.042 14.4 2.8 0.057 14.0 2.8 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 ORY38461.1 - 0.12 13.0 4.7 0.33 11.6 4.7 1.8 1 1 0 1 1 1 0 SlyX Cep57_MT_bd PF06657.13 ORY38461.1 - 0.13 12.7 3.5 1.7 9.2 0.8 2.2 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 XhlA PF10779.9 ORY38461.1 - 0.14 12.3 2.3 0.29 11.4 2.3 1.5 1 0 0 1 1 1 0 Haemolysin XhlA Fib_alpha PF08702.10 ORY38461.1 - 0.15 12.2 3.3 0.49 10.6 3.2 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 ORY38461.1 - 0.25 11.8 2.6 1.1 9.8 2.9 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 ORY38461.1 - 0.62 9.9 5.3 6.3 6.7 0.4 2.0 1 1 1 2 2 2 0 Septum formation initiator Neural_ProG_Cyt PF06567.11 ORY38463.1 - 4.9e-09 36.4 1.4 3.6 7.8 0.0 4.8 1 1 4 5 5 5 4 Neural chondroitin sulphate proteoglycan cytoplasmic domain ARTD15_N PF18084.1 ORY38463.1 - 2.8e-07 30.7 1.5 6.1 7.2 0.0 4.4 1 1 3 4 4 4 4 ARTD15 N-terminal domain MRP-S24 PF14955.6 ORY38463.1 - 5.1e-06 26.5 0.0 15 5.6 0.0 4.0 1 1 3 4 4 4 4 Mitochondrial ribosome subunit S24 PAP2_3 PF14378.6 ORY38463.1 - 5.7e-05 22.9 2.3 15 5.2 0.0 4.0 1 1 3 4 4 4 4 PAP2 superfamily Lantibiotic_a PF14867.6 ORY38463.1 - 0.00061 19.5 0.0 1.2e+02 2.5 0.0 5.0 5 0 0 5 5 5 0 Lantibiotic alpha Bravo_FIGEY PF13882.6 ORY38463.1 - 0.0013 20.0 0.2 42 5.6 0.0 3.7 1 1 3 4 4 4 0 Bravo-like intracellular region DUF2278 PF10042.9 ORY38463.1 - 0.063 13.3 0.2 35 4.3 0.0 3.1 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2278) Diacid_rec PF05651.13 ORY38463.1 - 0.17 11.6 0.2 88 2.8 0.0 4.0 5 0 0 5 5 5 0 Putative sugar diacid recognition PhnG PF06754.12 ORY38466.1 - 0.86 9.6 0.0 0.86 9.6 0.0 2.5 2 0 0 2 2 2 0 Phosphonate metabolism protein PhnG OB_NTP_bind PF07717.16 ORY38513.1 - 1.1e-26 92.9 0.0 2.4e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 ORY38513.1 - 2.9e-26 91.9 0.2 2.9e-26 91.9 0.2 2.8 2 1 0 2 2 1 1 Helicase associated domain (HA2) S1 PF00575.23 ORY38513.1 - 1.1e-08 35.3 0.3 2.5e-08 34.2 0.3 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Helicase_C PF00271.31 ORY38513.1 - 5.9e-05 23.4 0.0 0.00099 19.4 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 ORY38513.1 - 8.8e-05 22.8 0.0 0.00035 20.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 ORY38513.1 - 0.00014 21.7 0.2 0.00053 19.8 0.2 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 ORY38513.1 - 0.001 18.8 0.0 0.0029 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY38513.1 - 0.029 14.7 0.0 0.078 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 ORY38513.1 - 0.046 13.7 0.0 4.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Microtubule binding SRP54 PF00448.22 ORY38513.1 - 0.049 13.3 0.1 0.095 12.3 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SSE PF00437.20 ORY38513.1 - 0.051 12.6 0.0 0.14 11.2 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_14 PF13173.6 ORY38513.1 - 0.086 12.9 0.1 0.62 10.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 ORY38513.1 - 0.71 9.2 2.8 13 5.0 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family Redoxin PF08534.10 ORY38514.1 - 1.6e-12 47.3 0.0 2.1e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 ORY38514.1 - 9.4e-12 45.1 0.0 1.3e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 ORY38514.1 - 4e-11 42.9 0.0 5.3e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin PF00085.20 ORY38514.1 - 1.3e-06 28.3 0.1 2.1e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin DUF953 PF06110.11 ORY38514.1 - 0.0078 15.8 0.1 0.012 15.2 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 ORY38514.1 - 0.0088 15.8 0.1 0.043 13.6 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY38514.1 - 0.15 12.5 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain DUF899 PF05988.12 ORY38514.1 - 0.18 11.3 0.0 0.22 11.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) Methyltransf_16 PF10294.9 ORY38515.1 - 2e-07 30.9 0.1 3.9e-07 30.0 0.1 1.5 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 ORY38515.1 - 0.0031 17.4 0.0 0.0036 17.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 ORY38515.1 - 0.044 13.4 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_31 PF13847.6 ORY38515.1 - 0.14 11.9 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain ASH PF15780.5 ORY38516.1 - 3.7e-07 30.2 6.6 3.2 8.0 1.0 8.2 8 1 0 8 8 8 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 ORY38516.1 - 5.4e-07 29.7 0.0 0.0012 18.9 0.0 3.5 3 0 0 3 3 3 2 Flagellar-associated PapD-like Transglut_C PF00927.22 ORY38516.1 - 0.00012 22.2 0.0 7.4 6.8 0.0 5.0 4 2 0 4 4 4 2 Transglutaminase family, C-terminal ig like domain fn3_5 PF06280.12 ORY38516.1 - 0.015 16.0 0.2 1 10.1 0.0 4.0 4 0 0 4 4 4 0 Fn3-like domain DUF1081 PF06448.11 ORY38516.1 - 0.04 14.3 0.4 0.34 11.3 0.0 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1081) DUF1997 PF09366.10 ORY38516.1 - 0.065 13.4 0.1 0.21 11.7 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1997) JmjC PF02373.22 ORY38518.1 - 4.6e-12 46.4 0.0 4.9e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 ORY38518.1 - 0.00024 20.9 0.0 0.00083 19.1 0.0 1.8 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 ORY38518.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Cupin domain Pyr_redox_2 PF07992.14 ORY38519.1 - 5.3e-32 111.2 0.0 6.3e-32 111.0 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY38519.1 - 2.3e-17 63.2 0.0 3.2e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY38519.1 - 4.4e-14 52.8 0.4 7.2e-14 52.1 0.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 ORY38519.1 - 0.013 15.9 0.1 0.023 15.1 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding K_oxygenase PF13434.6 ORY38519.1 - 0.047 12.8 0.0 0.17 11.0 0.0 1.8 1 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 ORY38519.1 - 0.077 12.3 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY38519.1 - 0.14 11.2 1.1 3.2 6.7 0.1 2.3 1 1 1 2 2 2 0 FAD binding domain RIFIN PF02009.16 ORY38520.1 - 0.7 9.7 6.8 7.5 6.3 0.3 2.2 2 0 0 2 2 2 0 Rifin EBP50_C PF09007.11 ORY38520.1 - 3 8.8 13.0 4.5 8.3 2.1 2.3 2 0 0 2 2 2 0 EBP50, C-terminal PH_12 PF16457.5 ORY38520.1 - 5.3 7.6 8.8 15 6.1 2.9 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Pex14_N PF04695.13 ORY38520.1 - 5.4 7.6 14.6 9.5 6.9 3.7 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Avl9 PF09794.9 ORY38521.1 - 2.9e-05 22.9 0.2 4.3e-05 22.4 0.2 1.2 1 0 0 1 1 1 1 Transport protein Avl9 Baculo_PEP_C PF04513.12 ORY38521.1 - 0.074 13.1 0.2 0.14 12.2 0.2 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Goodbye PF17109.5 ORY38521.1 - 0.36 11.3 1.8 0.42 11.1 0.5 1.9 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Avl9 PF09794.9 ORY38522.1 - 5.1e-70 236.1 0.1 8.7e-69 232.0 0.1 2.5 1 1 0 1 1 1 1 Transport protein Avl9 DENN PF02141.21 ORY38522.1 - 0.00016 21.7 0.4 0.00025 21.1 0.4 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain DUF2347 PF09804.9 ORY38522.1 - 0.001 18.7 0.2 0.11 12.1 0.4 3.2 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.10 ORY38522.1 - 0.0021 18.0 0.4 2.2 8.3 0.0 2.8 3 0 0 3 3 3 2 Stabilization of polarity axis Coatomer_E PF04733.14 ORY38523.1 - 8.8e-75 251.8 7.1 1e-74 251.6 7.1 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 ORY38523.1 - 2.9e-09 37.3 13.4 7.1e-05 23.2 0.7 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY38523.1 - 5.4e-05 23.3 0.8 0.36 11.1 0.1 2.8 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 ORY38523.1 - 0.016 15.8 4.6 3.5 8.5 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY38523.1 - 0.031 14.0 0.4 0.4 10.4 0.1 2.6 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.17 ORY38523.1 - 0.19 11.9 1.7 0.97 9.7 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY38523.1 - 1.9 9.2 6.0 2.2 9.0 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Pro_isomerase PF00160.21 ORY38524.1 - 6.2e-46 156.6 0.0 6.9e-46 156.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.25 ORY38525.1 - 1.5e-59 201.6 0.0 7.3e-44 150.1 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY38525.1 - 3.7e-23 82.1 0.0 2e-15 56.8 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY38525.1 - 0.00021 20.7 0.1 0.018 14.4 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 ORY38525.1 - 0.18 10.7 0.0 3 6.7 0.0 2.0 1 1 0 2 2 2 0 Haspin like kinase domain LRR_4 PF12799.7 ORY38526.1 - 2.5e-21 75.4 43.9 1.9e-05 24.9 3.4 6.2 2 1 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY38526.1 - 6.1e-20 70.8 44.4 3.8e-08 33.0 9.8 5.3 2 2 3 5 5 5 5 Leucine rich repeat LRR_1 PF00560.33 ORY38526.1 - 1.7e-08 33.8 39.9 0.049 14.2 1.3 10.5 10 0 0 10 10 10 3 Leucine Rich Repeat SAM_3 PF18016.1 ORY38526.1 - 0.00041 20.1 0.3 3.5 7.5 0.0 3.4 2 1 1 3 3 3 3 SAM domain (Sterile alpha motif) LRR_9 PF14580.6 ORY38526.1 - 2.7 7.4 12.9 0.91 9.0 0.1 3.0 1 1 1 3 3 3 0 Leucine-rich repeat LRR_6 PF13516.6 ORY38526.1 - 4.7 7.5 38.7 8.5 6.7 0.3 9.1 10 0 0 10 10 10 0 Leucine Rich repeat LRR_8 PF13855.6 ORY38527.1 - 2e-14 53.1 25.7 1.4e-08 34.4 3.9 4.4 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY38527.1 - 1.7e-12 47.3 18.6 0.032 14.7 0.2 4.8 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY38527.1 - 4.4e-05 23.5 21.4 0.46 11.2 0.7 6.4 6 1 0 6 6 6 3 Leucine Rich Repeat F-box-like PF12937.7 ORY38527.1 - 0.00027 20.7 1.2 0.0023 17.8 0.9 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 ORY38527.1 - 0.035 14.0 0.4 0.035 14.0 0.4 2.5 3 0 0 3 3 3 0 F-box domain LRR_9 PF14580.6 ORY38527.1 - 0.12 11.9 2.1 8.9 5.8 0.2 2.3 2 0 0 2 2 2 0 Leucine-rich repeat LRR_8 PF13855.6 ORY38528.1 - 1.2e-17 63.4 34.1 2.1e-10 40.2 6.1 4.3 5 0 0 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 ORY38528.1 - 3.5e-13 49.5 35.5 6.7e-07 29.5 3.1 6.6 3 3 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY38528.1 - 4e-09 35.8 28.2 0.031 14.8 0.2 8.5 7 1 1 8 8 8 4 Leucine Rich Repeat LRR_6 PF13516.6 ORY38528.1 - 7.1e-06 25.7 18.7 0.87 9.8 0.3 6.7 6 0 0 6 6 6 3 Leucine Rich repeat F-box-like PF12937.7 ORY38528.1 - 0.0012 18.7 0.5 0.0031 17.4 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY38528.1 - 0.0024 17.7 0.7 0.0076 16.1 0.3 2.1 2 0 0 2 2 2 1 F-box domain LRR_2 PF07723.13 ORY38528.1 - 0.051 14.3 0.1 35 5.3 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_9 PF14580.6 ORY38528.1 - 1.1 8.7 7.4 5.6 6.4 0.2 3.1 1 1 2 3 3 3 0 Leucine-rich repeat LRR_8 PF13855.6 ORY38529.1 - 4.1e-15 55.3 19.4 2.6e-09 36.7 2.5 4.0 2 1 3 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 ORY38529.1 - 1.2e-10 41.5 17.9 9.6e-05 22.7 0.7 5.2 2 1 5 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY38529.1 - 6e-08 32.2 15.6 0.37 11.5 0.0 7.0 5 3 1 6 6 6 3 Leucine Rich Repeat SAM_3 PF18016.1 ORY38529.1 - 0.0062 16.3 0.0 0.54 10.1 0.0 2.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) MitoNEET_N PF10660.9 ORY38529.1 - 0.064 13.3 0.1 2 8.5 0.0 2.9 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus LRR_6 PF13516.6 ORY38529.1 - 1.7 8.9 14.6 27 5.1 0.1 5.5 6 0 0 6 6 6 0 Leucine Rich repeat Gly_transf_sug PF04488.15 ORY38530.1 - 9.2e-09 35.8 0.0 1.8e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 ORY38530.1 - 0.0039 16.6 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 ORY38530.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain adh_short PF00106.25 ORY38531.1 - 8.4e-18 64.5 0.0 3.2e-13 49.6 0.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY38531.1 - 1.7e-09 37.6 0.0 2.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY38531.1 - 0.068 13.1 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 KR domain adh_short PF00106.25 ORY38532.1 - 2.1e-13 50.2 0.0 4e-08 33.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY38532.1 - 1e-08 35.1 0.0 1.5e-05 24.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase TB2_DP1_HVA22 PF03134.19 ORY38534.1 - 1.5e-27 95.3 6.4 1.5e-27 95.3 6.4 1.8 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Fib_alpha PF08702.10 ORY38534.1 - 0.1 12.8 0.1 0.15 12.3 0.1 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family GST_N_3 PF13417.6 ORY38535.1 - 8.2e-10 39.0 0.0 1.7e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY38535.1 - 1.2e-09 38.3 0.0 2.5e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 ORY38535.1 - 4.7e-05 23.5 0.1 0.00023 21.3 0.1 2.0 2 0 0 2 2 2 1 Glutaredoxin GST_C_2 PF13410.6 ORY38535.1 - 0.0027 17.7 0.1 0.008 16.2 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 ORY38535.1 - 0.005 17.4 0.0 0.012 16.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY38535.1 - 0.051 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Lipase_3 PF01764.25 ORY38536.1 - 9.2e-22 77.4 0.0 4.9e-17 62.1 0.0 2.2 1 1 1 2 2 2 2 Lipase (class 3) DUF2974 PF11187.8 ORY38536.1 - 0.12 12.0 0.1 6.2 6.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) RRM_1 PF00076.22 ORY38537.1 - 1.8e-30 104.5 1.0 2e-17 62.8 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY38537.1 - 0.00016 21.8 0.1 0.12 12.5 0.0 2.9 2 2 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 ORY38537.1 - 0.023 14.3 0.0 3 7.4 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 ORY38537.1 - 0.077 12.8 0.0 0.27 11.0 0.0 1.9 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain Limkain-b1 PF11608.8 ORY38537.1 - 0.13 12.4 0.2 12 6.1 0.0 2.5 2 0 0 2 2 2 0 Limkain b1 DUF1387 PF07139.11 ORY38537.1 - 0.42 10.3 5.8 0.73 9.5 5.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Mitofilin PF09731.9 ORY38537.1 - 5 5.8 18.4 0.08 11.8 10.0 1.8 2 0 0 2 2 2 0 Mitochondrial inner membrane protein CDC45 PF02724.14 ORY38538.1 - 0.015 13.7 1.7 0.015 13.6 1.7 1.1 1 0 0 1 1 1 0 CDC45-like protein CD99L2 PF12301.8 ORY38538.1 - 0.028 14.7 5.6 0.039 14.3 5.6 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 Herpes_DNAp_acc PF04929.12 ORY38538.1 - 0.17 10.8 2.9 0.22 10.5 2.9 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF913 PF06025.12 ORY38538.1 - 0.33 9.9 2.5 0.39 9.6 2.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NOA36 PF06524.12 ORY38538.1 - 3.8 6.8 13.3 0.094 12.0 7.2 1.4 2 0 0 2 2 2 0 NOA36 protein HSF_DNA-bind PF00447.17 ORY38539.1 - 3.6e-32 110.8 5.9 4.3e-32 110.6 5.9 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding DUF1919 PF08942.10 ORY38539.1 - 0.006 16.1 0.8 0.0068 15.9 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1919) Ribosomal_L30 PF00327.20 ORY38539.1 - 0.17 11.8 0.1 1 9.3 0.0 2.0 1 1 1 2 2 2 0 Ribosomal protein L30p/L7e Mito_carr PF00153.27 ORY38540.1 - 7.8e-47 157.1 11.1 1.6e-19 69.6 0.3 4.1 3 2 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY38540.1 - 0.017 14.3 0.0 2 7.5 0.0 2.4 2 0 0 2 2 2 0 Gammaproteobacterial serine protease Mito_carr PF00153.27 ORY38541.1 - 1.8e-57 191.3 5.1 2.2e-19 69.2 0.4 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY38541.1 - 0.045 12.9 0.0 2 7.5 0.0 2.5 2 0 0 2 2 2 0 Gammaproteobacterial serine protease Membr_traf_MHD PF10540.9 ORY38542.1 - 4.5e-11 43.1 0.0 8.1e-05 22.8 0.0 2.6 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain CCT PF06203.14 ORY38542.1 - 0.18 11.8 1.4 0.29 11.2 0.3 1.8 2 0 0 2 2 2 0 CCT motif Apis_Csd PF11671.8 ORY38543.1 - 0.0041 17.1 0.2 0.0041 17.1 0.2 3.4 1 1 2 3 3 3 1 Complementary sex determiner protein BTB PF00651.31 ORY38544.1 - 1.1e-13 51.3 0.1 5.4e-12 45.9 0.1 2.3 2 0 0 2 2 2 1 BTB/POZ domain SPRY PF00622.28 ORY38544.1 - 9.5e-05 22.5 0.0 0.00016 21.7 0.0 1.4 1 0 0 1 1 1 1 SPRY domain RP-C PF03428.13 ORY38544.1 - 0.18 11.4 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain PhoLip_ATPase_C PF16212.5 ORY38546.1 - 1.1e-70 238.2 22.3 1.1e-70 238.2 22.3 3.0 3 0 0 3 3 3 2 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY38546.1 - 3.4e-16 58.7 2.1 1.1e-15 57.0 2.1 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 ORY38546.1 - 2.6e-13 49.9 0.0 3.3e-12 46.3 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY38546.1 - 3.6e-12 47.0 1.2 3.3e-07 30.8 0.2 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORY38546.1 - 1.1e-08 34.8 0.3 1.1e-08 34.8 0.3 2.5 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 ORY38546.1 - 0.00061 19.6 0.4 0.032 14.0 0.4 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 ORY38547.1 - 4.3e-07 29.6 0.0 0.0011 18.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY38547.1 - 0.02 14.2 0.0 2 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.25 ORY38548.1 - 2.5e-35 122.1 0.0 3.4e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY38548.1 - 3.3e-24 85.6 0.0 8.4e-24 84.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY38548.1 - 0.0015 17.4 0.1 0.0025 16.7 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY38548.1 - 0.004 16.5 0.0 0.0064 15.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY38548.1 - 0.039 13.3 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY38548.1 - 0.1 12.5 0.2 0.16 11.8 0.2 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family PH PF00169.29 ORY38551.1 - 0.0018 18.8 0.0 0.0043 17.5 0.0 1.6 1 0 0 1 1 1 1 PH domain Git3 PF11710.8 ORY38552.1 - 0.00011 22.1 1.6 0.00013 21.8 1.6 1.1 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Frizzled PF01534.17 ORY38552.1 - 0.00014 21.0 1.7 0.00016 20.9 1.7 1.1 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Phageshock_PspG PF09583.10 ORY38552.1 - 0.078 13.3 3.7 0.11 12.8 3.7 1.2 1 0 0 1 1 1 0 Phage shock protein G (Phageshock_PspG) E1-E2_ATPase PF00122.20 ORY38552.1 - 1.3 8.5 3.9 2.3 7.7 3.9 1.4 1 1 1 2 2 2 0 E1-E2 ATPase 7tm_1 PF00001.21 ORY38553.1 - 0.00018 21.0 2.2 0.00022 20.7 2.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 ORY38553.1 - 0.012 15.4 2.9 0.012 15.4 2.9 1.8 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 DUF1600 PF07667.11 ORY38553.1 - 1.7 8.8 6.9 5.5 7.2 6.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1600) HORMA PF02301.18 ORY38554.1 - 1.4e-05 24.8 0.1 2.6e-05 23.9 0.1 1.4 1 1 0 1 1 1 1 HORMA domain Peptidase_M54 PF07998.11 ORY38554.1 - 0.065 13.2 0.0 0.12 12.3 0.0 1.4 1 1 0 1 1 1 0 Peptidase family M54 Polysacc_deac_1 PF01522.21 ORY38555.1 - 1.3e-10 41.2 0.0 2.3e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase ArAE_2 PF10334.9 ORY38557.1 - 1.3e-07 31.7 0.3 0.0048 16.8 0.1 2.8 2 1 0 2 2 2 2 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 ORY38557.1 - 0.00027 20.1 0.3 0.00027 20.1 0.3 2.4 3 1 0 3 3 3 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 ORY38557.1 - 0.0017 18.4 4.9 0.0017 18.4 4.9 3.2 4 0 0 4 4 4 1 Fusaric acid resistance protein-like ALMT PF11744.8 ORY38557.1 - 0.0037 16.2 0.0 0.015 14.2 0.0 2.0 2 0 0 2 2 2 1 Aluminium activated malate transporter CPP1-like PF11833.8 ORY38557.1 - 3.2 7.4 6.2 0.28 10.8 0.7 2.0 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Pkinase_Tyr PF07714.17 ORY38558.1 - 8.6e-16 58.0 0.0 3.9e-15 55.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase LRR_8 PF13855.6 ORY38558.1 - 1.6e-12 46.9 6.7 3.1e-07 30.1 2.2 3.5 2 1 1 3 3 3 3 Leucine rich repeat Pkinase PF00069.25 ORY38558.1 - 3.3e-10 39.8 0.0 5.2e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 ORY38558.1 - 3e-08 33.8 10.3 0.046 14.1 1.3 4.6 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) Kdo PF06293.14 ORY38558.1 - 2.2e-06 27.2 0.0 3.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY38558.1 - 0.0032 16.8 0.0 0.007 15.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY38558.1 - 0.0062 16.5 0.0 0.0096 15.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORY38558.1 - 0.2 11.2 0.1 0.48 10.0 0.0 1.5 2 0 0 2 2 2 0 RIO1 family LRR_1 PF00560.33 ORY38558.1 - 0.41 11.4 11.8 4.8 8.1 0.3 4.7 4 2 0 4 4 4 0 Leucine Rich Repeat SWIRM PF04433.17 ORY38559.1 - 3.6e-26 91.3 0.1 8.9e-26 90.1 0.0 1.8 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.31 ORY38559.1 - 2.8e-08 33.8 0.1 5.1e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY38559.1 - 2.4e-05 24.5 0.1 5.2e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 ORY38559.1 - 0.0045 16.8 0.1 0.01 15.7 0.1 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-HYPF PF07503.12 ORY38559.1 - 0.055 13.3 0.7 0.18 11.6 0.7 1.8 1 0 0 1 1 1 0 HypF finger PH PF00169.29 ORY38560.1 - 0.086 13.4 0.0 0.35 11.4 0.0 2.1 1 0 0 1 1 1 0 PH domain Glyco_hydro_3_C PF01915.22 ORY38561.1 - 7.1e-101 336.3 0.0 5.5e-56 189.7 0.0 2.5 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORY38561.1 - 2e-60 204.8 0.0 9.5e-33 113.9 0.0 2.9 2 1 0 2 2 2 2 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORY38561.1 - 5.9e-33 112.8 0.5 4e-18 65.3 0.0 2.4 2 0 0 2 2 2 2 Fibronectin type III-like domain CAP PF00188.26 ORY38561.1 - 2.8e-06 28.2 0.1 7.2e-06 26.8 0.1 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TBP-binding PF09247.11 ORY38561.1 - 0.014 15.7 0.1 7.7 6.9 0.0 2.9 3 0 0 3 3 3 0 TATA box-binding protein binding CagZ PF09053.10 ORY38561.1 - 0.13 11.8 0.0 6.7 6.3 0.0 2.4 2 0 0 2 2 2 0 CagZ RDD PF06271.12 ORY38562.1 - 0.32 11.2 3.0 0.82 9.9 0.1 2.1 2 0 0 2 2 2 0 RDD family DUF2408 PF10303.9 ORY38563.1 - 0.35 11.4 10.9 0.032 14.8 2.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) LMBR1 PF04791.16 ORY38563.1 - 3.1 6.6 3.4 7 5.4 3.5 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein Cnn_1N PF07989.11 ORY38563.1 - 8.7 6.6 9.3 0.39 10.9 0.4 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 PRP38 PF03371.15 ORY38564.1 - 4.1e-55 186.3 1.6 5.5e-55 185.9 1.6 1.2 1 0 0 1 1 1 1 PRP38 family Glycos_transf_1 PF00534.20 ORY38565.1 - 1.1e-11 44.6 0.0 1.5e-10 40.9 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY38565.1 - 7e-08 33.0 0.0 1.9e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 FH2 PF02181.23 ORY38565.1 - 0.091 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain PHP PF02811.19 ORY38566.1 - 4e-12 46.7 0.0 1.1e-11 45.3 0.0 1.7 1 1 0 1 1 1 1 PHP domain DUF3128 PF11326.8 ORY38567.1 - 9.6e-20 70.7 0.1 1.1e-19 70.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Glyco_hydro_3_C PF01915.22 ORY38568.1 - 3.8e-55 187.0 0.1 8.1e-55 185.9 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORY38568.1 - 7e-41 140.6 0.0 1.1e-40 140.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORY38568.1 - 4.9e-14 52.2 0.7 1e-13 51.2 0.7 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Amino_oxidase PF01593.24 ORY38568.1 - 0.044 13.1 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase SNF2_N PF00176.23 ORY38569.1 - 3.3e-57 193.8 0.0 5e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 ORY38569.1 - 4.9e-10 39.7 0.1 2.3e-09 37.5 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORY38569.1 - 4.9e-06 26.9 0.2 1.1e-05 25.7 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 ORY38569.1 - 0.00013 21.3 0.3 0.00024 20.4 0.3 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 ORY38569.1 - 0.0042 16.8 4.3 0.022 14.4 0.0 3.1 4 0 0 4 4 4 1 SWI2/SNF2 ATPase DUF1664 PF07889.12 ORY38570.1 - 0.018 15.1 2.6 0.66 10.0 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) NYD-SP28 PF14772.6 ORY38570.1 - 0.03 14.3 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Sperm tail T7SS_ESX_EspC PF10824.8 ORY38570.1 - 0.14 12.6 4.8 1.9 9.0 2.7 2.7 2 1 0 2 2 2 0 Excreted virulence factor EspC, type VII ESX diderm CytadhesinP1 PF12378.8 ORY38570.1 - 0.18 12.0 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 Trypsin-sensitive surface-exposed protein NTPase_I-T PF01931.18 ORY38571.1 - 9.6e-55 184.8 0.0 1.1e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 NTPase_I-T PF01931.18 ORY38572.1 - 3.4e-53 179.8 0.0 3.9e-53 179.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 DUF1746 PF08508.10 ORY38573.1 - 9.5e-09 35.6 4.9 1.1e-08 35.5 3.6 1.8 2 1 0 2 2 2 1 Fungal domain of unknown function (DUF1746) DUF5592 PF17332.2 ORY38573.1 - 0.091 13.3 1.2 0.19 12.3 0.3 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5592) DHHC PF01529.20 ORY38574.1 - 3.6e-17 62.7 22.9 3.6e-17 62.7 22.9 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ribosomal_L40e PF01020.17 ORY38574.1 - 0.029 14.2 2.2 0.05 13.5 2.2 1.3 1 0 0 1 1 1 0 Ribosomal L40e family Glyco_hydro_26 PF02156.15 ORY38575.1 - 9.9e-11 41.6 3.2 1.8e-10 40.8 3.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 DUF3673 PF12425.8 ORY38576.1 - 0.085 12.8 0.2 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3673) SSP160 PF06933.11 ORY38576.1 - 0.2 9.8 6.1 0.24 9.5 6.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 KRTAP PF11759.8 ORY38577.1 - 0.12 12.9 6.5 0.21 12.1 5.2 1.9 2 0 0 2 2 2 0 Keratin-associated matrix NDC10_II PF16787.5 ORY38580.1 - 0.032 13.3 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 DUF5344 PF17279.2 ORY38580.1 - 0.047 14.3 0.5 0.12 13.0 0.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5344) GCN5L1 PF06320.13 ORY38581.1 - 7.2e-30 103.5 1.4 8.7e-30 103.2 1.4 1.0 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Med10 PF09748.9 ORY38581.1 - 0.012 15.5 0.0 0.026 14.5 0.0 1.6 1 1 1 2 2 2 0 Transcription factor subunit Med10 of Mediator complex Erf4 PF10256.9 ORY38581.1 - 0.071 13.2 0.0 0.22 11.6 0.0 1.8 1 1 1 2 2 2 0 Golgin subfamily A member 7/ERF4 family Peptidase_Mx PF15887.5 ORY38581.1 - 0.076 12.4 0.1 0.085 12.2 0.1 1.1 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase Methyltransf_31 PF13847.6 ORY38583.1 - 0.00011 22.0 0.7 0.00027 20.8 0.6 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY38583.1 - 0.00012 21.9 0.0 0.00046 20.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY38583.1 - 0.0004 21.0 3.0 0.0028 18.3 1.7 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY38583.1 - 0.00056 20.5 0.4 0.0046 17.6 0.3 2.4 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 ORY38583.1 - 0.0035 16.8 0.1 0.0051 16.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ORY38583.1 - 0.05 13.2 0.1 0.086 12.4 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Adaptin_N PF01602.20 ORY38584.1 - 9.8e-49 166.3 5.0 1.2e-48 166.0 5.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ORY38584.1 - 0.0012 19.0 2.1 0.64 10.0 0.2 2.6 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORY38584.1 - 0.0021 18.1 0.2 3.1 8.3 0.0 3.6 3 0 0 3 3 3 2 HEAT repeat Vac14_Fab1_bd PF12755.7 ORY38584.1 - 0.18 12.4 3.4 2 9.1 0.1 3.3 2 2 1 4 4 4 0 Vacuolar 14 Fab1-binding region Cpn60_TCP1 PF00118.24 ORY38585.1 - 4.6e-150 500.5 3.1 1.5e-123 413.1 3.0 2.0 1 1 1 2 2 2 2 TCP-1/cpn60 chaperonin family AAA_6 PF12774.7 ORY38586.1 - 2.2e-155 516.6 0.0 6.3e-154 511.8 0.0 2.6 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 ORY38586.1 - 2.7e-135 452.2 9.7 2.7e-135 452.2 9.7 4.9 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 ORY38586.1 - 9.7e-119 397.0 2.3 9.7e-119 397.0 2.3 5.5 7 0 0 7 7 6 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 ORY38586.1 - 1.9e-94 316.4 0.1 3.4e-93 312.2 0.0 3.1 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 ORY38586.1 - 3.3e-91 304.3 0.1 3.3e-91 304.3 0.1 4.1 5 0 0 5 5 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 ORY38586.1 - 3.2e-72 243.0 3.3 2.1e-70 237.0 0.4 4.6 3 1 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 ORY38586.1 - 1e-60 204.3 7.4 1.9e-56 190.4 0.0 4.7 5 1 0 5 5 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 ORY38586.1 - 7.5e-56 188.5 0.1 1.8e-55 187.2 0.1 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 ORY38586.1 - 1.8e-54 185.1 10.7 1.8e-54 185.1 10.7 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 ORY38586.1 - 6.3e-46 155.3 0.0 2.4e-43 147.0 0.0 3.6 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 ORY38586.1 - 3.3e-30 104.8 0.1 5e-29 101.0 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 ORY38586.1 - 1.9e-28 99.2 1.3 2e-14 53.8 0.0 6.0 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 ORY38586.1 - 1.7e-19 69.9 4.2 8.5e-18 64.4 0.2 3.5 2 0 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 ORY38586.1 - 1.3e-10 41.8 0.9 0.00053 20.4 0.0 4.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY38586.1 - 3.6e-10 40.5 0.3 0.24 11.8 0.0 5.5 4 0 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 ORY38586.1 - 6.5e-08 32.9 0.1 0.11 12.8 0.0 4.3 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 ORY38586.1 - 2.1e-06 28.3 0.1 0.085 13.4 0.0 4.2 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 ORY38586.1 - 0.00036 20.9 0.3 1.3 9.4 0.0 4.1 3 0 0 3 3 3 1 RNA helicase RsgA_GTPase PF03193.16 ORY38586.1 - 0.0005 20.0 0.3 0.87 9.5 0.0 3.2 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 ORY38586.1 - 0.00074 19.3 1.6 9.2 5.9 0.1 3.6 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 ORY38586.1 - 0.0009 19.2 1.4 1.6 8.7 0.0 3.7 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 ORY38586.1 - 0.0019 17.7 0.1 0.82 9.0 0.1 3.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 ORY38586.1 - 0.0044 16.2 0.3 1.2 8.2 0.0 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF815) Roc PF08477.13 ORY38586.1 - 0.0052 17.0 0.8 0.84 9.9 0.0 3.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 ORY38586.1 - 0.0059 16.3 0.4 3.5 7.4 0.3 3.6 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 ORY38586.1 - 0.006 16.9 2.6 12 6.3 0.1 3.8 3 0 0 3 3 3 0 AAA domain Septin PF00735.18 ORY38586.1 - 0.0068 15.7 0.2 1.2 8.4 0.0 2.6 2 0 0 2 2 2 1 Septin AAA_24 PF13479.6 ORY38586.1 - 0.008 15.9 0.6 7.3 6.3 0.1 4.1 3 0 0 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.6 ORY38586.1 - 0.0091 16.1 0.0 6.7 6.8 0.0 3.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 ORY38586.1 - 0.0098 15.6 0.2 0.82 9.4 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_33 PF13671.6 ORY38586.1 - 0.011 15.8 1.8 8 6.6 0.2 3.7 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 ORY38586.1 - 0.024 14.4 1.4 8.3 6.2 0.1 2.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SSE PF00437.20 ORY38586.1 - 0.033 13.3 2.8 0.36 9.8 0.1 3.1 3 0 0 3 3 2 0 Type II/IV secretion system protein AAA_28 PF13521.6 ORY38586.1 - 0.052 13.8 1.4 2.9 8.1 0.2 3.5 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 ORY38586.1 - 0.075 13.1 0.5 23 5.1 0.0 3.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase P22_AR_C PF10548.9 ORY38586.1 - 0.27 11.5 1.4 0.63 10.2 0.2 2.4 2 0 0 2 2 1 0 P22AR C-terminal domain T3SSipB PF16535.5 ORY38586.1 - 0.63 10.5 26.7 0.5 10.8 0.1 5.1 4 0 0 4 4 4 0 Type III cell invasion protein SipB ABC_tran PF00005.27 ORY38586.1 - 3.2 8.3 10.7 3.8 8.0 0.1 4.3 4 0 0 4 4 2 0 ABC transporter DASH_Duo1 PF08651.10 ORY38586.1 - 3.2 7.6 11.9 4.8 7.0 0.2 5.1 4 0 0 4 4 4 0 DASH complex subunit Duo1 Actin PF00022.19 ORY38587.1 - 8.5e-45 153.1 0.0 5.3e-43 147.2 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 ORY38587.1 - 9.6e-12 44.3 0.0 1.2e-08 34.2 0.0 2.3 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 ORY38587.1 - 0.013 15.9 0.0 0.074 13.5 0.0 2.1 1 1 0 1 1 1 0 Cell division protein FtsA DUF1640 PF07798.11 ORY38588.1 - 1.5e-23 83.7 10.6 2.5e-23 83.0 10.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Acetyltransf_1 PF00583.25 ORY38589.1 - 0.0075 16.5 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF4242 PF14026.6 ORY38589.1 - 0.052 13.7 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) DUF3285 PF11688.8 ORY38589.1 - 0.64 10.0 0.0 0.64 10.0 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3285) ABC_membrane PF00664.23 ORY38590.1 - 5.9e-45 154.0 25.6 6.8e-34 117.8 13.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY38590.1 - 6.4e-45 153.0 0.0 3.8e-27 95.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY38590.1 - 9e-09 35.1 0.9 0.1 12.0 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY38590.1 - 8e-07 29.6 0.3 0.077 13.4 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 ORY38590.1 - 3.8e-06 26.6 0.4 0.054 13.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ORY38590.1 - 2.5e-05 24.6 0.1 0.4 10.9 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 ORY38590.1 - 5.7e-05 23.1 0.8 0.36 10.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORY38590.1 - 0.00039 20.4 0.2 1.5 8.7 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ORY38590.1 - 0.00047 20.2 0.0 0.057 13.5 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 ORY38590.1 - 0.0015 18.5 0.1 0.84 9.5 0.0 2.5 2 0 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 ORY38590.1 - 0.0017 18.3 0.0 1.1 9.1 0.0 2.7 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea FtsK_SpoIIIE PF01580.18 ORY38590.1 - 0.0019 17.6 0.0 0.72 9.2 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_15 PF13175.6 ORY38590.1 - 0.0019 18.0 0.0 0.27 10.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 ORY38590.1 - 0.0035 17.9 0.2 1.7 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 ORY38590.1 - 0.0045 17.1 0.8 1.5 8.9 0.1 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain Roc PF08477.13 ORY38590.1 - 0.0048 17.1 0.3 4.3 7.6 0.0 3.3 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase tRNA_lig_kinase PF08303.11 ORY38590.1 - 0.0082 16.2 0.0 0.052 13.6 0.0 2.2 2 0 0 2 2 2 1 tRNA ligase kinase domain Zeta_toxin PF06414.12 ORY38590.1 - 0.01 15.1 0.1 1 8.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 ORY38590.1 - 0.013 15.8 0.0 1.4 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.15 ORY38590.1 - 0.019 13.8 0.4 0.87 8.3 0.1 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_5 PF07728.14 ORY38590.1 - 0.019 14.9 0.2 0.8 9.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 ORY38590.1 - 0.026 14.1 0.1 1.8 8.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Ras PF00071.22 ORY38590.1 - 0.035 13.7 0.1 5.3 6.6 0.0 2.6 2 0 0 2 2 2 0 Ras family IIGP PF05049.13 ORY38590.1 - 0.041 12.9 0.1 0.12 11.3 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Viral_helicase1 PF01443.18 ORY38590.1 - 0.044 13.5 0.6 4.4 7.0 0.1 2.6 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 ORY38590.1 - 0.05 12.7 0.3 7.6 5.5 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 ORY38590.1 - 0.051 13.0 0.1 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 ORY38590.1 - 0.051 13.3 0.0 7.3 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 ORY38590.1 - 0.061 12.5 0.1 0.32 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 ORY38590.1 - 0.11 12.6 0.0 8.3 6.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ORY38590.1 - 0.12 11.9 0.6 10 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 ORY38590.1 - 0.26 11.3 1.2 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Dynamin family Glu_dehyd_C PF16912.5 ORY38592.1 - 1.5e-10 40.9 0.1 4.5e-08 32.8 0.1 2.4 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N PF00107.26 ORY38592.1 - 4.3e-06 26.7 0.2 1.8e-05 24.7 0.2 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY38592.1 - 0.00032 20.5 0.9 0.0024 17.7 0.9 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 ORY38592.1 - 0.0082 16.4 0.2 0.018 15.3 0.2 1.5 1 0 0 1 1 1 1 TrkA-N domain ADH_zinc_N_2 PF13602.6 ORY38592.1 - 0.009 17.1 0.4 0.058 14.4 0.0 2.4 3 1 0 3 3 3 1 Zinc-binding dehydrogenase Actin PF00022.19 ORY38593.1 - 2.8e-06 26.2 0.0 3.1e-06 26.1 0.0 1.0 1 0 0 1 1 1 1 Actin ATP-synt_C PF00137.21 ORY38594.1 - 6.2e-34 116.1 33.9 2e-22 79.3 12.7 2.4 3 0 0 3 3 3 2 ATP synthase subunit C Peroxin-3 PF04882.12 ORY38598.1 - 1.5 7.7 0.0 1.5 7.7 0.0 2.3 2 0 0 2 2 2 0 Peroxin-3 RNA_pol_3_Rpc31 PF11705.8 ORY38600.1 - 0.0021 18.3 11.9 0.0042 17.4 11.9 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.12 ORY38600.1 - 0.098 12.4 11.5 0.17 11.6 11.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Taeniidae_ag PF05596.11 ORY38600.1 - 0.11 12.5 0.0 0.77 9.8 0.0 2.5 3 0 0 3 3 3 0 Taeniidae antigen CNDH2_C PF16858.5 ORY38600.1 - 0.56 10.0 9.3 0.5 10.2 5.6 2.2 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Glyco_hydro_18 PF00704.28 ORY38601.1 - 6.7e-10 39.2 0.0 1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Abhydrolase_3 PF07859.13 ORY38602.1 - 3.2e-05 23.9 0.1 5.2e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY38602.1 - 0.00014 21.2 0.0 0.11 11.7 0.0 2.5 2 1 0 2 2 2 2 Serine aminopeptidase, S33 COesterase PF00135.28 ORY38602.1 - 0.0054 15.7 0.0 0.0081 15.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Acetyltransf_9 PF13527.7 ORY38603.1 - 3.1e-17 62.8 0.0 5.4e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY38603.1 - 7.7e-09 35.6 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY38603.1 - 2.3e-07 31.0 0.0 1.1e-06 28.9 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY38603.1 - 2.4e-05 24.7 0.0 5.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 ORY38603.1 - 0.053 13.0 0.0 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase FR47 PF08445.10 ORY38603.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Pro_isomerase PF00160.21 ORY38604.1 - 2.4e-48 164.4 0.1 2.7e-48 164.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD BP28CT PF08146.12 ORY38605.1 - 1.3e-26 93.3 0.8 1.3e-26 93.3 0.8 3.0 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 ORY38605.1 - 5.5e-10 39.6 0.0 5.5e-10 39.6 0.0 6.4 8 1 0 9 9 9 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 ORY38605.1 - 0.0035 17.5 0.7 14 6.3 0.1 5.5 5 0 0 5 5 5 1 HEAT repeat Erf4 PF10256.9 ORY38605.1 - 0.022 14.9 0.3 2.9 8.0 0.1 3.4 3 0 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family HEAT_2 PF13646.6 ORY38605.1 - 0.027 14.9 2.7 22 5.5 0.1 5.4 6 0 0 6 6 6 0 HEAT repeats TolA_bind_tri PF16331.5 ORY38605.1 - 0.12 12.4 0.0 7.1 6.8 0.0 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation Condensin2nSMC PF12422.8 ORY38605.1 - 1.4 9.1 7.5 3.1 7.9 0.6 4.6 4 1 1 5 5 5 0 Condensin II non structural maintenance of chromosomes subunit Cellulase PF00150.18 ORY38606.1 - 3.9e-13 49.5 0.1 7.3e-07 28.9 0.0 2.1 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 ORY38606.1 - 0.0012 18.3 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 ORY38606.1 - 0.068 12.8 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 Glyco_hydro_5_C PF18564.1 ORY38606.1 - 0.15 12.6 0.0 0.56 10.8 0.0 1.9 2 0 0 2 2 2 0 Glycoside hydrolase family 5 C-terminal domain LRR_8 PF13855.6 ORY38607.1 - 8.1e-05 22.3 0.0 0.0015 18.2 0.0 2.3 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 ORY38607.1 - 0.52 10.8 3.5 1.7 9.2 0.7 2.9 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) DUF3157 PF11355.8 ORY38607.1 - 0.55 9.8 6.3 0.84 9.2 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) LRR_8 PF13855.6 ORY38608.1 - 1e-07 31.6 0.1 0.0022 17.7 0.0 2.4 2 0 0 2 2 2 2 Leucine rich repeat RAC_head PF16717.5 ORY38610.1 - 3.1e-09 37.7 4.5 3.1e-09 37.7 4.5 2.8 2 1 0 2 2 2 1 Ribosome-associated complex head domain DnaJ PF00226.31 ORY38610.1 - 0.03 14.5 8.9 1.6 8.9 0.0 4.6 4 0 0 4 4 4 0 DnaJ domain DUF4136 PF13590.6 ORY38610.1 - 0.034 14.7 1.7 0.097 13.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4136) CemA PF03040.14 ORY38610.1 - 0.061 13.2 4.9 0.098 12.6 4.9 1.4 1 0 0 1 1 1 0 CemA family Gaa1 PF04114.14 ORY38611.1 - 7.9e-83 279.2 0.0 1.4e-82 278.3 0.0 1.3 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component Glyco_hydro_3_C PF01915.22 ORY38612.1 - 4.7e-57 193.2 0.0 9.8e-57 192.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 ORY38612.1 - 1.3e-20 74.1 0.8 2.6e-19 69.8 0.2 2.1 1 1 1 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 ORY38612.1 - 7.6e-17 61.2 0.6 1.8e-16 60.0 0.6 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain Rft-1 PF04506.13 ORY38614.1 - 2.6e-128 429.0 7.9 3.2e-128 428.7 7.9 1.0 1 0 0 1 1 1 1 Rft protein NDK PF00334.19 ORY38616.1 - 8.8e-19 67.9 0.0 9.8e-19 67.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF4928 PF16280.5 ORY38617.1 - 0.021 14.1 0.1 0.029 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4928) HSP70 PF00012.20 ORY38618.1 - 5e-178 593.0 1.2 5.9e-178 592.8 1.2 1.0 1 0 0 1 1 1 1 Hsp70 protein NDK PF00334.19 ORY38618.1 - 4.1e-47 159.6 0.0 7.1e-47 158.8 0.0 1.4 1 0 0 1 1 1 1 Nucleoside diphosphate kinase MreB_Mbl PF06723.13 ORY38618.1 - 6.3e-15 54.8 0.3 2.5e-14 52.8 0.2 1.9 2 0 0 2 2 2 1 MreB/Mbl protein Imm17 PF15562.6 ORY38619.1 - 0.075 12.9 6.0 0.1 12.5 1.9 2.5 2 0 0 2 2 2 0 Immunity protein 17 WD40 PF00400.32 ORY38620.1 - 2.5e-43 145.2 30.4 9.9e-09 35.7 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY38620.1 - 1.9e-14 53.7 7.1 0.011 16.0 0.1 6.0 1 1 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY38620.1 - 2.5e-07 30.8 1.7 0.055 13.3 0.1 3.4 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 ORY38620.1 - 0.00012 20.2 4.1 0.00041 18.5 3.1 2.3 1 1 0 1 1 1 1 IKI3 family Coatomer_WDAD PF04053.14 ORY38620.1 - 0.047 12.7 0.9 0.15 11.1 0.2 2.0 2 0 0 2 2 2 0 Coatomer WD associated region YmzC PF14157.6 ORY38620.1 - 0.16 12.1 0.1 5 7.3 0.0 3.1 3 0 0 3 3 3 0 YmzC-like protein Amino_oxidase PF01593.24 ORY38621.1 - 2.4e-18 66.7 0.0 4.3e-18 65.8 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY38621.1 - 2e-13 50.4 0.1 9.4e-13 48.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY38621.1 - 2.2e-07 30.8 0.0 0.00017 21.3 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY38621.1 - 3.2e-07 29.9 0.0 0.0048 16.2 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY38621.1 - 5.7e-05 22.5 0.2 0.0001 21.7 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 ORY38621.1 - 0.00018 20.9 0.0 0.0011 18.4 0.0 1.9 2 0 0 2 2 2 1 ThiF family Pyr_redox PF00070.27 ORY38621.1 - 0.00038 21.0 0.2 0.11 13.1 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY38621.1 - 0.00069 19.6 0.4 0.42 10.6 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 ORY38621.1 - 0.0016 17.7 0.0 0.0029 16.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ORY38621.1 - 0.0036 16.1 0.1 0.063 12.0 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 ORY38621.1 - 0.022 13.8 0.1 0.054 12.6 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 ORY38621.1 - 0.035 13.4 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 ORY38621.1 - 0.084 11.9 0.0 0.45 9.5 0.0 2.1 3 0 0 3 3 3 0 Lycopene cyclase protein SgrR_N PF12793.7 ORY38621.1 - 0.17 12.1 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 Sugar transport-related sRNA regulator N-term FAD_oxidored PF12831.7 ORY38621.1 - 0.24 10.7 0.0 0.63 9.3 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase COX7C PF02935.16 ORY38623.1 - 4.9 7.5 6.3 18 5.7 0.5 2.3 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc V_ATPase_I PF01496.19 ORY38625.1 - 0.34 8.8 1.2 0.39 8.6 1.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 ORY38625.1 - 3.1 6.5 3.9 3.6 6.3 3.9 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 ORY38625.1 - 8.8 5.0 9.0 9.8 4.8 9.0 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 zf-MYND PF01753.18 ORY38627.1 - 1.3e-10 41.2 17.1 2.3e-10 40.4 17.1 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY38627.1 - 2.4 8.5 15.0 1.9 8.8 10.0 2.4 2 1 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 ORY38627.1 - 8.8 6.3 16.2 0.29 11.0 8.1 2.3 2 0 0 2 2 2 0 HIT zinc finger UCH PF00443.29 ORY38628.1 - 3.2e-56 190.7 0.0 5.7e-56 189.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY38628.1 - 1.9e-16 60.6 0.5 1e-06 28.6 0.1 3.3 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 ORY38628.1 - 0.091 12.5 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin family Pga1 PF10333.9 ORY38630.1 - 0.00028 20.8 0.0 0.0025 17.7 0.0 2.0 2 0 0 2 2 2 1 GPI-Mannosyltransferase II co-activator Pur_ac_phosph_N PF16656.5 ORY38630.1 - 0.017 15.7 0.0 0.028 15.0 0.0 1.5 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain CARDB PF07705.11 ORY38630.1 - 0.03 14.6 0.0 0.051 13.8 0.0 1.3 1 0 0 1 1 1 0 CARDB fn3 PF00041.21 ORY38630.1 - 0.14 12.5 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III domain Tim17 PF02466.19 ORY38631.1 - 8.7e-06 26.1 0.2 1.3e-05 25.6 0.2 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Ribosomal_S3_C PF00189.20 ORY38632.1 - 2.8e-23 82.2 1.1 9.8e-23 80.5 1.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 ORY38632.1 - 6.7e-12 45.1 0.1 1.2e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 ORY38632.1 - 0.18 11.6 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Coilin N-terminus TPR_12 PF13424.6 ORY38633.1 - 1.6e-56 188.5 27.3 2.1e-11 43.9 1.0 7.6 4 3 4 8 8 8 7 Tetratricopeptide repeat TPR_10 PF13374.6 ORY38633.1 - 6e-24 83.2 10.3 1.6e-06 27.8 0.2 8.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY38633.1 - 7.8e-22 77.6 7.7 0.026 15.0 0.1 8.4 4 2 5 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 ORY38633.1 - 3.9e-18 64.0 11.2 0.65 10.3 0.0 9.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY38633.1 - 3.9e-14 52.8 6.1 1.9e-05 24.2 0.1 3.1 2 1 0 3 3 3 3 MalT-like TPR region TPR_8 PF13181.6 ORY38633.1 - 1.2e-13 50.1 10.9 0.93 9.9 0.0 9.4 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY38633.1 - 1.1e-11 43.9 18.5 0.88 9.7 0.2 8.5 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 ORY38633.1 - 3.6e-11 42.9 11.5 4.2 8.5 0.0 9.1 7 2 2 9 9 9 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY38633.1 - 2.2e-10 39.9 8.6 1.3 8.9 0.1 8.6 10 0 0 10 10 10 3 Tetratricopeptide repeat PPR PF01535.20 ORY38633.1 - 1.6e-09 37.3 2.9 1.9 8.9 0.0 8.3 9 0 0 9 9 8 1 PPR repeat TPR_16 PF13432.6 ORY38633.1 - 3.3e-08 34.0 13.0 0.012 16.2 1.0 6.7 6 2 0 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 ORY38633.1 - 1.2e-06 28.7 1.5 3.4 8.0 0.1 5.7 5 1 3 8 8 7 2 Tetratricopeptide repeat RPN6_N PF18055.1 ORY38633.1 - 3.1e-05 24.3 0.5 4.7 7.6 0.0 4.4 3 2 1 5 5 5 1 26S proteasome regulatory subunit RPN6 N-terminal domain ANAPC3 PF12895.7 ORY38633.1 - 0.00012 22.2 9.2 0.22 11.8 0.4 6.1 5 3 2 7 7 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 ORY38633.1 - 0.0018 18.8 15.9 16 6.4 0.1 7.6 8 0 0 8 8 8 0 Tetratricopeptide repeat SNAP PF14938.6 ORY38633.1 - 0.0061 16.0 8.0 0.19 11.1 0.2 3.7 2 1 2 4 4 4 1 Soluble NSF attachment protein, SNAP TPR_3 PF07720.12 ORY38633.1 - 0.008 16.2 8.7 0.28 11.2 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF269 PF03270.13 ORY38633.1 - 0.1 12.7 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF269 ER-remodelling PF14755.6 ORY38633.1 - 0.15 12.4 2.2 0.42 10.9 2.2 1.8 1 0 0 1 1 1 0 Intracellular membrane remodeller pPIWI_RE_Z PF18155.1 ORY38633.1 - 0.18 11.6 4.8 18 5.1 0.1 3.7 3 1 0 3 3 3 0 pPIWI RE three-gene island domain Z TPR_11 PF13414.6 ORY38633.1 - 0.71 9.6 7.0 21 4.9 0.0 4.8 6 0 0 6 6 6 0 TPR repeat TPR_4 PF07721.14 ORY38633.1 - 1.1 10.1 4.2 72 4.5 0.0 4.1 4 0 0 4 4 2 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 ORY38633.1 - 3 7.9 9.8 78 3.3 0.0 5.9 6 1 0 6 6 5 0 Mad3/BUB1 homology region 1 PsbN PF02468.15 ORY38634.1 - 9.4 6.2 12.1 6.4 6.7 1.5 3.6 3 0 0 3 3 3 0 Photosystem II reaction centre N protein (psbN) Ank_4 PF13637.6 ORY38635.1 - 9.4e-08 32.5 1.4 0.33 11.6 0.1 5.4 3 1 4 7 7 7 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY38635.1 - 2.6e-06 28.0 0.0 0.047 14.3 0.0 3.6 3 2 0 3 3 3 2 Ankyrin repeats (3 copies) DUF4891 PF16232.5 ORY38635.1 - 0.0055 17.2 0.0 16 6.1 0.0 4.4 5 1 1 6 6 6 1 Domain of unknown function (DUF4891) Ank_4 PF13637.6 ORY38637.1 - 1.2e-05 25.7 0.1 10 6.9 0.0 4.8 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY38637.1 - 0.0093 16.5 0.0 0.06 13.9 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) F-box PF00646.33 ORY38637.1 - 0.0098 15.7 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain Citrate_bind PF16114.5 ORY38638.1 - 2.7e-90 300.6 0.0 5.2e-90 299.7 0.0 1.5 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding Citrate_synt PF00285.21 ORY38638.1 - 6.7e-19 68.2 0.0 2.1e-16 59.9 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 ORY38638.1 - 1.7e-14 53.9 0.1 4.3e-14 52.6 0.1 1.8 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.19 ORY38638.1 - 1.2e-11 45.1 0.0 3e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.10 ORY38638.1 - 7.9e-08 32.1 0.0 2.3e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain Succ_CoA_lig PF13607.6 ORY38638.1 - 6.6e-07 29.2 1.6 1e-05 25.3 0.0 3.1 3 0 0 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain UQ_con PF00179.26 ORY38639.1 - 2.6e-32 111.4 0.0 3.1e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TPH PF13868.6 ORY38641.1 - 8.6e-08 31.1 8.8 1e-07 30.8 8.8 1.0 1 0 0 1 1 1 1 Trichohyalin-plectin-homology domain Utp21 PF04192.12 ORY38641.1 - 0.015 14.8 1.8 0.022 14.3 1.8 1.2 1 1 0 1 1 1 0 Utp21 specific WD40 associated putative domain Ribosomal_S17 PF00366.20 ORY38643.1 - 2.9e-13 49.7 0.2 7.4e-13 48.4 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 Ala_racemase_N PF01168.20 ORY38646.1 - 5.4e-24 85.1 0.0 6.9e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain BSD PF03909.17 ORY38647.1 - 4.4e-14 52.2 0.2 1.1e-13 51.0 0.2 1.7 1 0 0 1 1 1 1 BSD domain DUF1719 PF08224.11 ORY38647.1 - 0.004 16.3 0.1 0.058 12.5 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF1719) ORC4_C PF14629.6 ORY38647.1 - 0.1 12.0 0.0 0.29 10.4 0.0 1.8 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 4 C-terminus DUF4694 PF15765.5 ORY38647.1 - 0.15 12.1 0.6 0.28 11.2 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4694) DUF948 PF06103.11 ORY38647.1 - 3.8 7.8 7.4 6.2 7.2 3.2 3.3 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Nucleo_P87 PF07267.11 ORY38648.1 - 0.22 10.3 2.0 0.24 10.2 2.0 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 APG12 PF04110.13 ORY38649.1 - 3.1e-35 120.4 0.0 3.5e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 ORY38649.1 - 0.00012 22.2 0.0 0.00014 22.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Ufm1 PF03671.14 ORY38649.1 - 0.0017 18.4 0.1 0.002 18.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein Pkinase PF00069.25 ORY38650.1 - 3.3e-37 128.3 0.0 4e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY38650.1 - 3.2e-30 105.3 0.0 4.5e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY38650.1 - 0.00019 20.8 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 ORY38650.1 - 0.01 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 ORY38650.1 - 0.029 13.4 0.3 0.05 12.7 0.3 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 ORY38650.1 - 0.031 13.6 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lipase_GDSL PF00657.22 ORY38651.1 - 4.9e-07 29.9 0.1 1.3e-06 28.6 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY38651.1 - 4.3e-06 27.2 0.0 1.7e-05 25.3 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY38652.1 - 3.2e-05 24.0 0.0 4.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY38652.1 - 0.0021 18.5 0.0 0.0036 17.7 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY38653.1 - 7e-10 39.2 0.0 9.8e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY38653.1 - 0.00035 21.0 0.0 0.00046 20.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family HSP20 PF00011.21 ORY38654.1 - 6.8e-27 93.6 0.9 9.7e-27 93.1 0.9 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORY38654.1 - 3.1e-11 42.6 0.0 7.2e-11 41.5 0.0 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA FKBP26_C PF18046.1 ORY38654.1 - 0.0045 17.0 0.4 0.063 13.4 0.1 2.1 2 0 0 2 2 2 1 FKBP26_C-terminal CS PF04969.16 ORY38654.1 - 0.0096 16.9 0.0 0.013 16.5 0.0 1.2 1 0 0 1 1 1 1 CS domain GvpH PF05455.11 ORY38654.1 - 0.025 14.7 0.5 0.066 13.3 0.1 1.8 1 1 1 2 2 2 0 GvpH LSM PF01423.22 ORY38654.1 - 0.045 13.5 0.0 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 LSM domain GlcV_C_terminal PF17847.1 ORY38654.1 - 0.066 13.7 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Glucose ABC transporter C-terminal domain Sfi1 PF08457.10 ORY38656.1 - 3.8e-07 29.0 11.3 1.1e-06 27.6 11.2 1.5 1 1 0 1 1 1 1 Sfi1 spindle body protein Sfi1 PF08457.10 ORY38657.1 - 9.8e-14 50.8 86.8 3.9e-07 29.0 39.8 5.4 3 2 1 4 4 4 4 Sfi1 spindle body protein RHD_DNA_bind PF00554.22 ORY38657.1 - 0.57 10.1 2.4 0.97 9.4 0.3 2.4 3 0 0 3 3 3 0 Rel homology DNA-binding domain YchF-GTPase_C PF06071.13 ORY38658.1 - 7.2e-33 112.6 0.2 7.2e-33 112.6 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 ORY38658.1 - 1e-21 77.2 0.0 2e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY38658.1 - 2.2e-08 33.8 0.0 3.8e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Cupin_2 PF07883.11 ORY38658.1 - 0.053 13.2 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Roc PF08477.13 ORY38658.1 - 0.13 12.4 0.0 0.67 10.2 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TGS PF02824.21 ORY38658.1 - 0.14 12.2 0.1 0.48 10.5 0.1 1.9 1 1 0 1 1 1 0 TGS domain Glyco_hydro_18 PF00704.28 ORY38659.1 - 3e-13 50.2 0.2 4.3e-13 49.7 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 FAD_binding_3 PF01494.19 ORY38660.1 - 1.1e-25 90.7 0.8 4e-24 85.5 0.8 2.2 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 ORY38660.1 - 0.00099 18.2 0.0 0.0046 16.0 0.0 1.9 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 ORY38660.1 - 0.0051 17.0 0.9 0.012 15.9 0.9 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY38660.1 - 0.0078 15.8 0.7 0.014 15.0 0.7 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ORY38660.1 - 0.14 11.2 0.6 0.24 10.4 0.6 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ORY38660.1 - 0.17 10.9 1.7 0.3 10.1 1.7 1.4 1 0 0 1 1 1 0 FAD binding domain HEAT PF02985.22 ORY38661.1 - 1.3e-41 137.0 28.9 0.00066 19.7 0.1 13.5 14 0 0 14 14 14 10 HEAT repeat HEAT_2 PF13646.6 ORY38661.1 - 1.7e-31 108.4 21.0 2.6e-09 37.3 0.0 8.6 3 3 6 9 9 9 8 HEAT repeats Vac14_Fab1_bd PF12755.7 ORY38661.1 - 8e-15 55.2 1.1 9.6e-05 22.9 0.1 7.1 4 3 3 7 7 7 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 ORY38661.1 - 1.2e-09 38.4 16.1 0.0077 16.7 0.0 7.9 9 0 0 9 9 9 3 HEAT-like repeat Cnd1 PF12717.7 ORY38661.1 - 2.4e-08 34.2 9.1 0.018 15.1 0.1 4.8 3 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 ORY38661.1 - 3e-08 33.8 5.5 0.0044 17.2 0.0 4.6 5 0 0 5 5 5 3 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 ORY38661.1 - 4.6e-05 22.2 10.4 0.064 11.8 0.3 3.9 2 1 0 3 3 3 2 Adaptin N terminal region IFRD PF05004.13 ORY38661.1 - 0.0004 19.6 3.5 0.048 12.8 0.6 4.0 3 1 1 4 4 4 2 Interferon-related developmental regulator (IFRD) CLASP_N PF12348.8 ORY38661.1 - 0.00063 19.4 1.7 2.1 7.9 0.1 4.3 3 2 1 4 4 4 2 CLASP N terminal Ecm29 PF13001.7 ORY38661.1 - 0.0055 15.4 2.4 2.8 6.5 0.1 3.5 3 0 0 3 3 3 2 Proteasome stabiliser IQ PF00612.27 ORY38662.1 - 1.3e-16 58.8 46.0 0.00035 20.1 1.3 8.5 8 0 0 8 8 8 7 IQ calmodulin-binding motif DUF3080 PF11279.8 ORY38662.1 - 0.22 10.7 4.9 1.2 8.3 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3080) Sel1 PF08238.12 ORY38663.1 - 4.4e-42 141.6 15.6 5.1e-08 33.3 0.0 9.9 11 0 0 11 11 10 7 Sel1 repeat TPR_1 PF00515.28 ORY38663.1 - 6.4e-21 73.2 17.5 0.00021 21.0 0.0 10.6 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY38663.1 - 4.8e-16 57.5 33.4 0.0001 22.1 0.3 10.7 11 1 1 12 12 12 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORY38663.1 - 8.3e-11 41.4 17.5 1.1e-06 28.1 0.5 6.5 6 1 1 7 7 7 2 TPR repeat TPR_9 PF13371.6 ORY38663.1 - 4.5e-10 39.5 1.8 0.00016 21.7 0.1 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY38663.1 - 3.6e-09 36.4 8.2 0.15 12.5 0.1 7.0 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY38663.1 - 4e-09 36.0 33.2 9.8e-05 22.3 1.6 10.1 11 1 0 11 11 11 2 Tetratricopeptide repeat zf-MYND PF01753.18 ORY38663.1 - 6.9e-09 35.7 14.2 1.5e-08 34.6 14.2 1.6 1 0 0 1 1 1 1 MYND finger ANAPC3 PF12895.7 ORY38663.1 - 5.3e-06 26.6 20.6 0.00029 21.0 4.1 4.6 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 ORY38663.1 - 0.0011 19.2 21.2 0.068 13.5 1.7 7.6 7 2 3 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY38663.1 - 0.0019 18.8 14.4 0.043 14.5 0.0 6.3 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY38663.1 - 0.0022 17.9 1.7 0.32 11.1 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY38663.1 - 0.003 18.2 13.4 0.077 13.9 0.2 7.0 5 2 3 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY38663.1 - 0.0056 17.2 0.1 0.0056 17.2 0.1 5.2 4 2 2 6 6 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 ORY38663.1 - 0.012 15.0 1.1 1.8 8.1 0.1 3.7 3 1 1 4 4 4 0 SHNi-TPR SGTA_dimer PF16546.5 ORY38663.1 - 0.014 15.1 0.9 0.029 14.1 0.1 2.0 2 0 0 2 2 2 0 Homodimerisation domain of SGTA TPR_15 PF13429.6 ORY38663.1 - 0.28 10.4 3.5 3 7.0 0.1 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat LSM PF01423.22 ORY38664.1 - 7.1e-11 41.6 0.2 1e-10 41.1 0.2 1.2 1 0 0 1 1 1 1 LSM domain LNS2 PF08235.13 ORY38664.1 - 0.018 14.5 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) dCache_1 PF02743.18 ORY38664.1 - 0.12 12.1 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Cache domain Adap_comp_sub PF00928.21 ORY38666.1 - 2.7e-22 79.4 0.0 3.9e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ORY38666.1 - 1.9e-07 31.1 0.0 3.1e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain GRP PF07172.11 ORY38666.1 - 0.15 12.8 13.0 0.3 11.8 13.0 1.4 1 0 0 1 1 1 0 Glycine rich protein family TraT PF05818.12 ORY38666.1 - 4.8 6.8 5.5 5.9 6.5 4.3 1.7 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Lipase_GDSL PF00657.22 ORY38667.1 - 9.1e-12 45.4 0.2 1.7e-11 44.5 0.2 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY38667.1 - 3.9e-06 27.4 1.0 2e-05 25.1 1.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PEP_mutase PF13714.6 ORY38667.1 - 0.12 11.8 1.6 0.22 10.9 1.6 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase DUF4865 PF16157.5 ORY38667.1 - 0.17 11.8 0.0 0.29 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4865) Lipase_GDSL PF00657.22 ORY38668.1 - 3.3e-12 46.8 0.3 5.2e-12 46.2 0.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY38668.1 - 2.2e-07 31.4 1.9 6.4e-07 29.9 1.9 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Tom37 PF10568.9 ORY38669.1 - 4.4e-21 75.5 0.0 7.4e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 ORY38669.1 - 1.7e-16 59.7 0.0 3.8e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 ORY38669.1 - 4.8e-13 49.7 0.0 9e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 ORY38669.1 - 1.2e-08 34.9 0.0 3.1e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY38669.1 - 0.00031 20.9 0.0 0.00063 19.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY38669.1 - 0.0013 18.8 0.0 0.0025 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FIBP PF05427.11 ORY38670.1 - 3.4e-70 237.1 0.8 1.1e-68 232.2 0.8 2.0 1 1 0 1 1 1 1 Acidic fibroblast growth factor binding (FIBP) Tfb4 PF03850.14 ORY38671.1 - 7e-77 258.6 0.8 8e-77 258.4 0.8 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Methyltransf_31 PF13847.6 ORY38672.1 - 7e-14 51.9 0.0 1.3e-13 51.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY38672.1 - 1.7e-10 41.4 0.0 3e-09 37.4 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY38672.1 - 1.8e-10 41.3 0.0 4.9e-09 36.8 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY38672.1 - 2.9e-08 34.3 0.0 5e-07 30.4 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY38672.1 - 2.2e-07 30.9 0.0 1e-06 28.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 ORY38672.1 - 0.0067 15.9 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.14 ORY38672.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Zn_clus PF00172.18 ORY38673.1 - 0.0001 22.4 10.5 0.00016 21.7 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OPT PF03169.15 ORY38674.1 - 9.8e-136 453.9 44.6 1.1e-135 453.7 44.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TraT PF05818.12 ORY38674.1 - 0.06 13.0 0.2 0.1 12.3 0.2 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein CbtB PF09489.10 ORY38674.1 - 0.53 10.4 2.1 3.3 7.9 0.3 3.4 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) Transgly_assoc PF04226.13 ORY38674.1 - 0.6 10.4 6.7 6.3 7.1 3.0 3.8 3 1 0 3 3 3 0 Transglycosylase associated protein HPP PF04982.13 ORY38674.1 - 2.6 8.3 11.0 1.2 9.3 1.4 3.9 3 1 0 3 3 3 0 HPP family zf-CRD PF17979.1 ORY38675.1 - 5.9e-28 98.0 4.9 5.9e-28 98.0 4.9 3.2 3 0 0 3 3 3 1 Cysteine rich domain with multizinc binding regions zf-C3HC4 PF00097.25 ORY38675.1 - 8.5e-09 35.1 7.9 8.5e-09 35.1 7.9 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY38675.1 - 9.2e-09 35.0 9.3 9.2e-09 35.0 9.3 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY38675.1 - 9.2e-09 35.5 8.8 9.2e-09 35.5 8.8 3.7 6 0 0 6 6 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORY38675.1 - 1.6e-07 31.0 5.8 1.6e-07 31.0 5.8 3.8 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY38675.1 - 9.8e-07 28.7 7.8 9.8e-07 28.7 7.8 3.2 4 0 0 4 4 3 1 RING-type zinc-finger zf-CCHH PF10283.9 ORY38675.1 - 2.5e-05 24.1 4.5 3.1e-05 23.9 1.3 2.7 2 0 0 2 2 2 1 PBZ domain zf-RING_5 PF14634.6 ORY38675.1 - 5.6e-05 23.0 7.2 5.6e-05 23.0 7.2 3.6 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORY38675.1 - 0.0001 22.3 8.8 0.0001 22.3 8.8 3.5 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 ORY38675.1 - 0.00013 21.8 2.9 0.00013 21.8 2.9 2.9 3 0 0 3 3 3 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 ORY38675.1 - 0.00027 20.7 8.1 0.00027 20.7 8.1 3.7 4 1 0 4 4 3 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 ORY38675.1 - 0.00027 21.0 3.2 0.00027 21.0 3.2 2.6 2 0 0 2 2 1 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 ORY38675.1 - 0.0034 17.6 9.3 0.0034 17.6 9.3 3.1 2 1 0 2 2 2 1 RING-H2 zinc finger domain CAP_N PF01213.19 ORY38675.1 - 0.26 10.7 8.8 0.46 9.9 8.8 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 ORY38675.1 - 0.42 10.7 6.9 0.92 9.6 6.9 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 ORY38675.1 - 8.2 6.4 11.7 16 5.4 11.7 1.5 1 1 0 1 1 1 0 Mitochondrial fission regulator zf-C2H2_4 PF13894.6 ORY38676.1 - 1.2e-06 28.8 5.2 0.0063 17.3 0.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY38676.1 - 1.1e-05 25.7 5.9 0.0054 17.1 0.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY38676.1 - 0.0033 17.8 6.5 0.27 11.7 0.4 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_3rep PF18868.1 ORY38676.1 - 0.0079 16.9 0.4 0.36 11.5 0.0 2.2 1 1 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats CPP1-like PF11833.8 ORY38676.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like zf-C2H2_6 PF13912.6 ORY38676.1 - 0.19 11.8 6.2 0.52 10.4 0.9 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger DAAD PF18752.1 ORY38676.1 - 2.1 8.1 6.8 0.58 10.0 2.4 1.9 2 1 0 2 2 2 0 Dictyosteliid AID/APOBEC-like Deaminase DUF5316 PF17247.2 ORY38677.1 - 0.029 14.4 0.1 0.038 14.0 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5316) zf-C2H2_4 PF13894.6 ORY38678.1 - 2.3e-09 37.3 3.1 0.00091 19.9 0.4 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY38678.1 - 6.1e-09 35.8 4.7 0.00051 20.4 0.5 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ORY38678.1 - 6.4e-07 29.2 1.9 0.0048 16.9 0.1 2.4 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY38678.1 - 3.6e-05 23.9 1.1 0.045 14.1 0.4 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY38678.1 - 0.00019 21.7 0.7 0.12 12.8 0.2 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 ORY38678.1 - 0.006 17.0 8.3 0.11 13.0 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger double domain LUC7 PF03194.15 ORY38678.1 - 0.068 12.8 2.2 0.086 12.5 2.2 1.4 1 1 0 1 1 1 0 LUC7 N_terminus zf-C2H2_2 PF12756.7 ORY38678.1 - 0.28 11.6 3.9 2.1 8.7 0.5 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) PHtD_u1 PF16645.5 ORY38679.1 - 0.04 14.3 5.6 0.051 14.0 5.6 1.2 1 0 0 1 1 1 0 Unstructured region on Pneumococcal histidine triad protein AflR PF08493.10 ORY38679.1 - 0.075 12.5 2.1 0.086 12.3 2.1 1.0 1 0 0 1 1 1 0 Aflatoxin regulatory protein zf-C2H2 PF00096.26 ORY38680.1 - 3.7e-09 36.5 2.7 0.00013 22.2 0.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY38680.1 - 1.5e-08 34.8 1.4 0.0053 17.5 0.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 ORY38680.1 - 9.7e-05 23.0 2.4 0.0047 17.6 0.3 3.0 1 1 2 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 ORY38680.1 - 0.0097 16.3 12.3 0.026 14.9 0.2 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY38680.1 - 0.076 13.0 1.4 8 6.6 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 ORY38680.1 - 2.1 8.7 5.4 0.35 11.2 0.7 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ogr_Delta PF04606.12 ORY38680.1 - 5.2 7.1 6.2 0.4 10.7 0.8 2.0 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2_4 PF13894.6 ORY38681.1 - 2e-05 25.0 3.4 0.0027 18.4 0.3 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY38681.1 - 3.6e-05 24.0 9.1 0.0067 16.8 0.1 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 ORY38681.1 - 0.1 13.3 2.9 0.86 10.3 0.3 2.3 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2 PF00096.26 ORY38684.1 - 2.7e-08 33.8 9.3 0.00013 22.2 2.8 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY38684.1 - 9.3e-07 29.2 6.9 0.0025 18.5 1.4 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ORY38684.1 - 0.0011 19.3 2.5 0.19 12.1 0.4 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 ORY38684.1 - 0.0023 18.3 10.2 0.11 13.0 0.9 2.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_8 PF15909.5 ORY38684.1 - 0.026 14.8 2.3 0.033 14.5 2.3 1.2 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 ORY38684.1 - 0.034 14.1 3.5 0.69 10.0 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger BolA PF01722.18 ORY38684.1 - 0.057 13.7 0.7 0.25 11.6 0.0 2.0 1 1 1 2 2 2 0 BolA-like protein zf-C2H2_jaz PF12171.8 ORY38684.1 - 0.097 13.0 3.4 0.28 11.5 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 ORY38684.1 - 1 9.5 5.3 5.3 7.1 0.9 2.4 1 1 1 2 2 2 0 BED zinc finger SAM_2 PF07647.17 ORY38685.1 - 2.6e-14 53.1 0.0 3e-14 52.9 0.0 1.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORY38685.1 - 6.3e-14 52.2 0.1 6.8e-14 52.1 0.1 1.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 ORY38685.1 - 0.0017 18.6 0.1 0.002 18.3 0.1 1.2 1 0 0 1 1 1 1 Ste50p, sterile alpha motif SAM_PNT PF02198.16 ORY38685.1 - 0.009 16.0 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain COBRA PF04833.15 ORY38686.1 - 0.034 14.1 0.0 0.94 9.4 0.0 2.2 2 0 0 2 2 2 0 COBRA-like protein Adeno_PV PF03910.13 ORY38688.1 - 0.0091 14.7 4.8 0.0098 14.6 4.8 1.2 1 0 0 1 1 1 1 Adenovirus minor core protein PV DDOST_48kD PF03345.14 ORY38688.1 - 0.11 11.4 0.4 0.12 11.2 0.4 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta TraG_N PF07916.11 ORY38688.1 - 0.81 8.5 8.7 0.94 8.3 8.7 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF1192 PF06698.11 ORY38690.1 - 0.0057 16.7 0.1 0.011 15.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) Circo_capsid PF02443.15 ORY38690.1 - 0.028 14.0 0.7 0.041 13.5 0.7 1.3 1 0 0 1 1 1 0 Circovirus capsid protein FSA_C PF10479.9 ORY38691.1 - 0.23 9.5 3.2 0.24 9.5 3.2 1.0 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus zf-C2H2 PF00096.26 ORY38692.1 - 1.2e-10 41.2 1.4 0.00045 20.5 0.4 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY38692.1 - 1.3e-09 38.1 3.6 0.00011 22.7 0.4 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY38692.1 - 7.5e-08 32.5 7.1 0.00021 21.6 0.1 2.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY38692.1 - 3.6e-07 30.0 3.3 0.0016 18.4 1.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY38692.1 - 0.00028 21.1 0.1 0.042 14.2 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 ORY38692.1 - 0.0012 19.1 1.3 0.0014 18.8 1.3 1.2 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 ORY38692.1 - 0.017 14.7 0.3 2.7 7.7 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2HC_2 PF13913.6 ORY38692.1 - 0.026 14.4 7.5 0.13 12.2 0.2 2.6 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-met PF12874.7 ORY38692.1 - 0.028 14.8 0.1 10 6.6 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 ORY38692.1 - 0.032 14.9 2.6 0.26 11.9 0.3 1.9 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats DUF5473 PF17567.2 ORY38692.1 - 0.047 14.0 0.2 0.052 13.8 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5473) zf-MYST PF17772.1 ORY38692.1 - 0.078 12.6 0.2 0.4 10.3 0.2 1.9 1 1 0 1 1 1 0 MYST family zinc finger domain Prok-RING_1 PF14446.6 ORY38692.1 - 0.083 12.8 1.9 2.1 8.3 1.9 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-TRAF PF02176.18 ORY38692.1 - 0.09 13.5 2.2 0.33 11.7 1.0 2.0 1 1 1 2 2 2 0 TRAF-type zinc finger zinc_ribbon_9 PF14369.6 ORY38692.1 - 0.11 12.8 1.5 11 6.4 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon TF_Zn_Ribbon PF08271.12 ORY38692.1 - 0.13 11.8 1.8 0.3 10.6 1.8 1.6 1 1 0 1 1 1 0 TFIIB zinc-binding DUF4764 PF15961.5 ORY38692.1 - 0.69 8.5 2.1 2.8 6.5 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4764) zf-C2H2_4 PF13894.6 ORY38693.1 - 2.9e-07 30.7 4.7 0.017 15.9 1.9 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY38693.1 - 1.4e-05 25.3 4.6 0.0028 18.0 0.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY38693.1 - 0.0062 16.9 5.8 0.15 12.5 0.3 3.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY38693.1 - 0.016 15.2 4.1 0.51 10.4 0.6 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 ORY38693.1 - 0.053 13.8 0.9 1.7 9.0 0.3 2.2 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 ORY38694.1 - 0.0001 22.9 8.5 0.059 14.2 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY38694.1 - 0.0039 17.2 3.1 0.0039 17.2 3.1 2.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY38694.1 - 0.007 16.8 10.1 0.018 15.5 0.2 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type HPIP PF15226.6 ORY38694.1 - 0.012 16.0 1.1 0.023 15.1 0.1 1.9 2 0 0 2 2 2 0 HCF-1 beta-propeller-interacting protein family DUF4298 PF14131.6 ORY38694.1 - 0.026 14.5 0.1 0.049 13.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) zf-H2C2_2 PF13465.6 ORY38694.1 - 0.07 13.6 8.2 0.29 11.6 1.3 2.9 3 0 0 3 3 3 0 Zinc-finger double domain Ogr_Delta PF04606.12 ORY38694.1 - 0.36 10.8 6.6 4.6 7.3 0.4 2.9 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger zf-C2H2_4 PF13894.6 ORY38696.1 - 1.2e-05 25.8 6.3 0.054 14.4 2.8 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY38696.1 - 0.00017 21.9 6.0 0.019 15.4 0.0 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY38696.1 - 0.0061 16.9 5.4 0.34 11.4 0.2 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY38696.1 - 0.012 15.5 3.9 0.11 12.5 2.0 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY38696.1 - 0.22 11.9 3.3 1.1 9.7 1.9 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn_clus PF00172.18 ORY38698.1 - 3.3e-05 23.9 8.2 6.1e-05 23.1 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 ORY38699.1 - 3.8e-05 23.7 10.5 7.2e-05 22.8 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 ORY38700.1 - 0.00063 19.8 11.0 0.0013 18.8 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1086 PF06461.11 ORY38700.1 - 0.14 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) Zn_clus PF00172.18 ORY38701.1 - 3.5e-07 30.2 10.2 5.6e-07 29.6 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BCDHK_Adom3 PF10436.9 ORY38703.1 - 6.8e-21 74.8 0.0 1.2e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase GTP_EFTU PF00009.27 ORY38704.1 - 3.4e-63 212.7 0.4 5.1e-63 212.1 0.4 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 ORY38704.1 - 1.1e-20 73.7 0.0 1e-19 70.5 0.0 2.4 1 1 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 ORY38704.1 - 1.2e-20 73.3 0.0 2.8e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORY38704.1 - 5.4e-07 29.9 1.3 1.6e-05 25.2 0.2 3.3 2 1 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 ORY38704.1 - 1.5e-05 25.0 0.4 0.00053 20.0 0.4 2.5 1 1 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 ORY38704.1 - 0.0023 18.0 0.1 0.0048 17.0 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ACPS PF01648.20 ORY38705.1 - 0.068 13.3 0.0 0.9 9.7 0.0 2.2 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase superfamily Tcf25 PF04910.14 ORY38707.1 - 5e-15 55.4 0.0 6.3e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 7TM_GPCR_Srt PF10321.9 ORY38744.1 - 0.075 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt PelD_GGDEF PF16963.5 ORY38744.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 PelD GGDEF domain DUF3531 PF12049.8 ORY38745.1 - 0.13 12.2 0.0 0.15 12.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3531) Tmemb_14 PF03647.13 ORY38746.1 - 1.8e-22 79.9 7.6 1.9e-22 79.8 7.6 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Tmemb_14 PF03647.13 ORY38747.1 - 4.1e-18 65.9 13.4 5.1e-18 65.6 13.4 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C OST3_OST6 PF04756.13 ORY38747.1 - 0.066 12.5 1.1 0.065 12.6 1.1 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Acyl-CoA_dh_1 PF00441.24 ORY38748.1 - 7.1e-32 110.7 2.3 1.1e-31 110.1 2.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY38748.1 - 2.7e-19 69.2 0.7 4.4e-19 68.5 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 ORY38748.1 - 5.8e-19 68.0 0.0 1e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 ORY38748.1 - 1.1e-12 48.6 0.1 2.9e-12 47.2 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY38748.1 - 2.3e-05 24.7 0.0 4.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Sugar_tr PF00083.24 ORY38749.1 - 3e-47 161.5 21.9 8.7e-47 160.0 21.9 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY38749.1 - 1.4e-22 80.2 32.6 4e-17 62.2 16.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORY38749.1 - 9.6e-06 25.1 3.9 9.6e-06 25.1 3.9 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 ORY38750.1 - 7e-46 157.0 25.8 1.6e-45 155.9 25.8 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY38750.1 - 2.7e-26 92.4 24.5 5e-20 71.7 11.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORY38750.1 - 0.00012 21.5 6.5 0.00012 21.5 6.5 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 ORY38751.1 - 3.2e-47 161.4 17.3 5.9e-47 160.6 17.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY38751.1 - 1.6e-23 83.3 31.4 1.6e-18 66.8 13.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORY38751.1 - 2.1e-05 24.0 3.4 2.1e-05 24.0 3.4 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 ORY38752.1 - 1.6e-48 165.7 21.8 3.7e-48 164.5 21.8 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY38752.1 - 3.1e-24 85.6 33.9 1.3e-18 67.1 13.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Endosulfine PF04667.17 ORY38753.1 - 7.3e-25 86.9 1.0 8.1e-25 86.8 1.0 1.0 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region SUIM_assoc PF16619.5 ORY38754.1 - 0.00032 20.7 0.7 0.00032 20.7 0.7 3.5 1 1 1 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 SRA1 PF07304.11 ORY38754.1 - 0.00035 20.4 1.3 0.00055 19.7 1.3 1.4 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.15 ORY38754.1 - 0.0037 17.3 0.1 0.0037 17.3 0.1 2.2 1 1 1 2 2 2 1 Prp18 domain Arf PF00025.21 ORY38754.1 - 0.17 11.3 1.1 0.23 10.9 0.9 1.4 1 1 0 1 1 1 0 ADP-ribosylation factor family TFIIA PF03153.13 ORY38754.1 - 1.8 8.5 26.2 2.1 8.3 26.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit T2SSC PF11356.8 ORY38754.1 - 9.1 6.2 14.5 9.6 6.1 11.1 2.1 1 1 1 2 2 2 0 Type II secretion system protein C DUF829 PF05705.14 ORY38755.1 - 4.2e-29 102.2 0.0 6.2e-29 101.6 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Ribosomal_60s PF00428.19 ORY38756.1 - 1.6e-25 89.5 14.8 2.3e-25 89.0 14.8 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 ORY38756.1 - 0.062 11.8 0.6 0.078 11.4 0.6 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Sugar_tr PF00083.24 ORY38757.1 - 3.7e-45 154.6 22.1 3.5e-43 148.1 22.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY38757.1 - 1.8e-20 73.2 36.9 4e-15 55.6 15.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORY38757.1 - 0.00011 21.6 8.2 0.00011 21.6 8.2 1.6 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Methyltransf_16 PF10294.9 ORY38758.1 - 1.5e-20 73.6 0.1 1.9e-20 73.3 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_28 PF02636.17 ORY38758.1 - 0.18 11.4 0.0 0.22 11.1 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase WD40 PF00400.32 ORY38759.1 - 6.7e-08 33.1 7.7 0.0024 18.6 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF3546 PF12066.8 ORY38760.1 - 7.4e-17 61.5 0.1 1.5e-16 60.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 ORY38760.1 - 1e-09 39.1 13.8 6.4e-09 36.5 13.8 2.2 1 1 0 1 1 1 1 Arsenite-resistance protein 2 zf-PHD-like PF15446.6 ORY38760.1 - 0.17 11.5 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-C2H2_4 PF13894.6 ORY38760.1 - 0.33 11.9 1.1 1.2 10.2 1.1 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY38760.1 - 6.4 7.4 5.5 1 9.9 1.0 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF3808 PF10300.9 ORY38761.1 - 1.7e-74 251.3 2.9 9.8e-38 130.1 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3808) TPR_8 PF13181.6 ORY38761.1 - 0.023 14.9 1.1 0.56 10.5 0.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY38761.1 - 1.3 9.3 7.1 1.1 9.5 0.5 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_trans_1_2 PF13524.6 ORY38762.1 - 0.00014 22.1 0.3 0.00029 21.1 0.3 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 TP6A_N PF04406.14 ORY38762.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Type IIB DNA topoisomerase ATP-cone PF03477.16 ORY38762.1 - 0.15 12.7 0.2 0.31 11.6 0.2 1.5 1 0 0 1 1 1 0 ATP cone domain Glyco_trans_1_2 PF13524.6 ORY38763.1 - 1.9e-05 25.0 0.2 3.8e-05 24.0 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 ATP-cone PF03477.16 ORY38763.1 - 0.014 15.9 0.1 0.031 14.8 0.1 1.5 1 0 0 1 1 1 0 ATP cone domain TP6A_N PF04406.14 ORY38763.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Type IIB DNA topoisomerase Phosphodiest PF01663.22 ORY38765.1 - 3.4e-80 270.3 0.2 4.3e-80 270.0 0.2 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.12 ORY38765.1 - 0.17 12.0 0.0 0.28 11.2 0.0 1.2 1 0 0 1 1 1 0 PglZ domain Pkinase PF00069.25 ORY38766.1 - 2.2e-64 217.4 0.0 3.6e-64 216.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY38766.1 - 6.5e-36 123.9 0.0 1.2e-35 123.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.22 ORY38766.1 - 2.8e-18 65.5 31.1 1.3e-10 41.0 15.1 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 ORY38766.1 - 1.1e-12 48.4 1.3 2.6e-12 47.2 1.3 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain HR1 PF02185.16 ORY38766.1 - 2.2e-11 43.7 25.5 3.3e-08 33.5 7.6 2.8 3 0 0 3 3 3 2 Hr1 repeat C2 PF00168.30 ORY38766.1 - 5.9e-08 32.9 0.0 1.3e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain Haspin_kinase PF12330.8 ORY38766.1 - 7.7e-05 21.8 0.1 7.7e-05 21.8 0.1 2.4 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 ORY38766.1 - 0.0042 16.4 1.5 0.024 13.9 0.0 2.5 3 0 0 3 3 3 1 Kinase-like WD40 PF00400.32 ORY38769.1 - 1.7e-19 69.8 3.0 6.5e-06 26.8 0.0 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY38769.1 - 4.1e-10 39.8 0.1 0.0051 17.1 0.0 3.9 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 ORY38769.1 - 0.0014 18.2 0.0 0.004 16.8 0.0 1.8 1 1 1 2 2 2 1 PQQ-like domain MMS1_N PF10433.9 ORY38769.1 - 0.0023 16.7 0.5 6 5.4 0.0 3.5 1 1 3 4 4 4 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term WD40_like PF17005.5 ORY38769.1 - 0.0084 15.5 0.5 0.33 10.2 0.0 2.5 2 1 0 2 2 2 1 WD40-like domain Nup160 PF11715.8 ORY38769.1 - 0.024 13.3 0.0 0.065 11.9 0.0 1.7 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Gmad1 PF10647.9 ORY38769.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain TTL PF03133.15 ORY38770.1 - 1.6e-76 257.3 0.2 1.6e-76 257.3 0.2 2.1 2 1 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 ORY38770.1 - 1.9e-05 24.1 4.6 0.035 13.4 0.0 3.2 3 0 0 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 ORY38770.1 - 0.0019 17.5 0.0 0.1 11.8 0.0 2.3 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp DUF2027 PF09640.10 ORY38770.1 - 0.24 11.0 3.0 0.47 10.0 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2027) SDA1 PF05285.12 ORY38770.1 - 1.3 8.4 19.2 3.2 7.1 19.2 1.6 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 ORY38770.1 - 4.4 5.5 14.0 10 4.3 14.0 1.5 1 0 0 1 1 1 0 CDC45-like protein UPF0220 PF05255.11 ORY38771.1 - 0.0016 18.1 0.1 0.003 17.1 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Pox_A14 PF05767.12 ORY38773.1 - 5.5 7.2 27.5 0.12 12.5 4.7 4.7 3 1 1 4 4 4 0 Poxvirus virion envelope protein A14 DUF3054 PF11255.8 ORY38773.1 - 9.2 6.8 12.3 0.75 10.3 2.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3054) Aminotran_5 PF00266.19 ORY38775.1 - 7.3e-46 156.8 0.0 8.3e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V SET PF00856.28 ORY38776.1 - 1.1e-14 55.2 0.0 2.1e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 SET domain DUF3522 PF12036.8 ORY38777.1 - 0.02 15.2 3.0 0.11 12.7 0.1 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3522) Serinc PF03348.15 ORY38777.1 - 0.41 9.5 7.8 0.33 9.8 1.5 2.2 2 0 0 2 2 2 0 Serine incorporator (Serinc) PHO4 PF01384.20 ORY38778.1 - 2.4e-103 345.7 19.8 2.9e-103 345.5 19.8 1.1 1 0 0 1 1 1 1 Phosphate transporter family DUF3337 PF11816.8 ORY38779.1 - 4.3e-23 82.0 0.1 4.6e-20 72.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.32 ORY38779.1 - 1.8e-22 79.2 28.2 3.2e-06 27.8 0.4 7.0 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY38779.1 - 0.0078 16.5 0.1 6.4 7.2 0.0 3.4 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CFEM PF05730.11 ORY38781.1 - 9.4e-05 22.4 19.7 0.016 15.3 6.2 2.5 2 0 0 2 2 2 2 CFEM domain Tweety PF04906.13 ORY38783.1 - 0.08 11.6 0.0 0.61 8.7 0.0 2.0 2 0 0 2 2 2 0 Tweety Arrestin_N PF00339.29 ORY38783.1 - 0.12 12.5 0.1 0.5 10.4 0.0 1.9 1 1 1 2 2 2 0 Arrestin (or S-antigen), N-terminal domain Glyco_trans_1_2 PF13524.6 ORY38784.1 - 0.00066 20.0 0.1 0.0013 19.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 MEKHLA PF08670.11 ORY38785.1 - 6.1e-14 52.1 0.0 7.6e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 MEKHLA domain Ribosomal_S19e PF01090.19 ORY38785.1 - 0.19 11.4 0.0 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S19e Acetyltransf_3 PF13302.7 ORY38786.1 - 4.1e-16 59.9 0.1 5.1e-16 59.6 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORY38786.1 - 0.0031 17.7 0.0 0.0041 17.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fucose_iso_N2 PF07882.12 ORY38786.1 - 0.061 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain Vac14_Fig4_bd PF11916.8 ORY38787.1 - 8.2e-76 253.6 5.8 1.6e-75 252.7 5.8 1.5 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 ORY38787.1 - 2.9e-42 143.2 0.6 6.6e-38 129.2 0.0 3.6 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.22 ORY38787.1 - 3.7e-12 45.4 3.2 0.027 14.7 0.0 6.9 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 ORY38787.1 - 2.1e-07 31.2 3.3 0.36 11.2 0.0 5.3 5 1 0 5 5 5 2 HEAT repeats CLASP_N PF12348.8 ORY38787.1 - 1.3e-05 24.9 0.1 0.0019 17.8 0.1 3.5 3 0 0 3 3 3 1 CLASP N terminal HEAT_EZ PF13513.6 ORY38787.1 - 3e-05 24.4 10.0 0.0026 18.2 0.3 5.3 5 0 0 5 5 5 1 HEAT-like repeat Cnd1 PF12717.7 ORY38787.1 - 5.9e-05 23.2 5.8 0.06 13.4 1.2 4.1 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Tti2 PF10521.9 ORY38787.1 - 0.002 17.7 0.4 1.2 8.6 0.0 4.1 4 0 0 4 4 4 1 Tti2 family PPL4 PF18188.1 ORY38787.1 - 0.0096 15.9 0.3 0.024 14.6 0.0 1.8 2 0 0 2 2 2 1 Prim-pol 4 RasGEF_N_2 PF14663.6 ORY38787.1 - 0.018 15.4 0.4 4.4 7.7 0.1 4.1 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Cohesin_HEAT PF12765.7 ORY38787.1 - 0.021 15.1 0.4 2.2 8.7 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Dopey_N PF04118.14 ORY38787.1 - 0.069 12.3 1.5 5.3 6.1 0.1 3.6 3 1 0 3 3 3 0 Dopey, N-terminal Arm PF00514.23 ORY38787.1 - 0.86 9.7 5.3 43 4.4 0.0 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Acetyltransf_3 PF13302.7 ORY38788.1 - 2e-25 90.0 0.1 2.4e-25 89.8 0.1 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY38788.1 - 2.7e-09 37.3 0.0 3.4e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 ORY38788.1 - 5.3e-07 29.9 0.0 7e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ORY38788.1 - 0.0055 16.4 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 ORY38788.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase Acyl-CoA_dh_1 PF00441.24 ORY38793.1 - 5.1e-33 114.4 0.7 8.3e-33 113.7 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 ORY38793.1 - 1e-16 60.8 0.0 2.6e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 ORY38793.1 - 1.1e-16 60.8 0.3 2.2e-16 59.8 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORY38793.1 - 5.2e-15 56.1 0.0 9.9e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY38793.1 - 3.2e-05 24.2 0.0 6.8e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Abhydrolase_3 PF07859.13 ORY38794.1 - 7.9e-47 159.8 0.0 1.3e-46 159.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY38794.1 - 1.5e-06 27.3 0.0 2.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Lipase_3 PF01764.25 ORY38794.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) COesterase PF00135.28 ORY38794.1 - 0.12 11.2 0.1 0.34 9.7 0.0 1.6 2 0 0 2 2 2 0 Carboxylesterase family Pkinase PF00069.25 ORY38795.1 - 2.7e-45 154.8 0.0 3e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY38795.1 - 2.3e-22 79.5 0.0 2.8e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY38795.1 - 1.4e-06 27.9 0.0 0.00098 18.5 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 ORY38795.1 - 0.0015 17.4 0.0 0.0017 17.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY38795.1 - 0.0018 17.3 0.0 0.0023 16.9 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain GDP_Man_Dehyd PF16363.5 ORY38796.1 - 1.3e-49 169.4 0.0 1.8e-49 169.0 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY38796.1 - 1.6e-49 168.5 0.0 2.3e-49 168.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY38796.1 - 1.4e-16 60.5 0.0 9.4e-16 57.8 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ORY38796.1 - 1.2e-15 57.3 0.0 1.7e-15 56.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ORY38796.1 - 5e-12 45.5 0.0 7.6e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ORY38796.1 - 3.1e-08 33.1 0.0 0.00011 21.4 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 ORY38796.1 - 7.8e-07 29.2 0.0 1.6e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 ORY38796.1 - 0.00037 20.5 0.0 0.76 9.7 0.0 2.4 2 0 0 2 2 2 2 KR domain NmrA PF05368.13 ORY38796.1 - 0.00098 18.7 0.1 0.007 16.0 0.0 2.2 2 1 0 2 2 2 1 NmrA-like family TrkA_N PF02254.18 ORY38796.1 - 0.0033 17.6 0.1 0.0063 16.8 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain DapB_N PF01113.20 ORY38796.1 - 0.082 13.0 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 ORY38796.1 - 0.14 12.4 0.8 0.38 11.0 0.1 2.1 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain DUF1800 PF08811.11 ORY38796.1 - 0.16 10.9 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Epimerase PF01370.21 ORY38797.1 - 1.5e-54 185.0 0.0 2e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY38797.1 - 1.1e-50 172.9 0.0 2.1e-50 172.0 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ORY38797.1 - 6.9e-19 67.9 0.0 2e-18 66.4 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ORY38797.1 - 1.3e-16 60.6 0.0 1.1e-15 57.5 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ORY38797.1 - 5.2e-13 48.7 0.0 9.5e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ORY38797.1 - 5.5e-09 35.6 0.0 6e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 ORY38797.1 - 1e-07 32.1 0.0 2e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY38797.1 - 1.2e-06 28.2 0.0 0.00063 19.4 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family KR PF08659.10 ORY38797.1 - 0.00072 19.5 0.4 0.068 13.1 0.4 2.4 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.18 ORY38797.1 - 0.007 16.6 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Sacchrp_dh_NADP PF03435.18 ORY38797.1 - 0.019 15.2 0.3 0.069 13.4 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 ORY38797.1 - 0.086 13.0 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF1800 PF08811.11 ORY38797.1 - 0.16 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) MFS_1 PF07690.16 ORY38798.1 - 3.2e-18 65.8 37.2 3.6e-11 42.6 17.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 ORY38798.1 - 3.2e-06 26.8 12.1 3.2e-06 26.8 12.1 2.6 3 0 0 3 3 3 1 Nodulin-like PIRT PF15099.6 ORY38798.1 - 0.18 11.4 3.0 1.4 8.5 0.1 3.2 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family MFS_1 PF07690.16 ORY38799.1 - 4.1e-18 65.4 30.6 1.7e-09 37.1 16.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 ORY38799.1 - 4.3e-06 26.4 11.3 4.3e-06 26.4 11.3 2.7 3 0 0 3 3 3 1 Nodulin-like Pkinase PF00069.25 ORY38800.1 - 1e-72 244.7 0.0 1.4e-72 244.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY38800.1 - 2e-45 155.1 0.0 2.9e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DNA_methylase PF00145.17 ORY38800.1 - 2.7e-29 102.6 0.0 6.2e-29 101.4 0.0 1.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Kinase-like PF14531.6 ORY38800.1 - 1e-06 28.3 0.1 5.9e-06 25.8 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORY38800.1 - 0.00036 19.4 0.3 0.00089 18.1 0.3 1.6 1 1 0 1 1 1 1 Fungal protein kinase RNA_pol_Rpc4 PF05132.14 ORY38800.1 - 0.026 14.9 5.8 3.2 8.2 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 Seadorna_VP7 PF07387.11 ORY38800.1 - 0.043 12.9 0.0 0.071 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.9 ORY38800.1 - 0.046 13.2 1.5 0.07 12.6 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DDHD PF02862.17 ORY38800.1 - 0.049 13.8 1.6 2.4 8.3 1.2 2.3 2 0 0 2 2 2 0 DDHD domain FTA2 PF13095.6 ORY38800.1 - 0.058 13.0 0.3 0.26 10.9 0.1 2.0 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 ORY38800.1 - 0.12 11.7 0.1 0.26 10.6 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cytomega_UL84 PF06284.11 ORY38800.1 - 0.33 9.4 1.8 0.56 8.6 1.8 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein TFIIA PF03153.13 ORY38800.1 - 9.5 6.1 19.7 0.13 12.3 7.5 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 ORY38802.1 - 5.9e-77 258.6 0.0 7.1e-77 258.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY38802.1 - 5.5e-44 150.4 0.0 6.5e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY38802.1 - 1.9e-07 30.7 0.0 4.9e-07 29.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 ORY38802.1 - 4.5e-05 23.1 0.5 7.2e-05 22.5 0.5 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 ORY38802.1 - 0.001 18.5 1.8 0.002 17.5 1.8 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY38802.1 - 0.0024 16.9 0.0 0.0031 16.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Vta1_C PF18097.1 ORY38802.1 - 0.005 16.5 0.1 3.2 7.5 0.0 2.5 2 0 0 2 2 2 2 Vta1 C-terminal domain APH PF01636.23 ORY38802.1 - 0.062 13.2 0.4 1 9.2 0.3 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 ORY38802.1 - 0.092 12.3 0.3 0.2 11.2 0.2 1.6 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL KA1 PF02149.19 ORY38803.1 - 6.4e-21 73.9 0.0 1e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Fungal_KA1 PF16797.5 ORY38803.1 - 0.0034 17.1 0.0 0.02 14.6 0.0 1.8 1 1 1 2 2 2 1 Fungal kinase associated-1 domain DUF4097 PF13349.6 ORY38804.1 - 0.0003 20.2 0.6 0.00047 19.6 0.6 1.3 1 0 0 1 1 1 1 Putative adhesin DUF4097 PF13349.6 ORY38805.1 - 0.017 14.4 0.8 0.076 12.3 0.8 1.9 1 1 0 1 1 1 0 Putative adhesin DUF4097 PF13349.6 ORY38806.1 - 2.7e-05 23.7 0.3 5e-05 22.8 0.3 1.4 1 1 0 1 1 1 1 Putative adhesin p450 PF00067.22 ORY38807.1 - 6.7e-77 259.2 0.9 7.7e-77 259.0 0.9 1.0 1 0 0 1 1 1 1 Cytochrome P450 CCDC92 PF14916.6 ORY38807.1 - 0.18 11.6 0.1 0.34 10.7 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain of unknown function p450 PF00067.22 ORY38808.1 - 7.2e-76 255.8 0.0 8.8e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4536 PF15055.6 ORY38809.1 - 0.0002 21.6 4.6 0.00026 21.2 4.1 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4536) NCE101 PF11654.8 ORY38809.1 - 0.039 13.7 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 Non-classical export protein 1 zf-C3HC4_3 PF13920.6 ORY38810.1 - 1.8e-05 24.5 11.5 3.4e-05 23.6 11.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY38810.1 - 3.9e-05 23.9 12.8 8.4e-05 22.8 12.8 1.6 1 0 0 1 1 1 1 Ring finger domain Sina PF03145.16 ORY38810.1 - 0.0027 17.7 0.2 0.0027 17.7 0.2 1.6 1 1 0 1 1 1 1 Seven in absentia protein family zf-C3HC4 PF00097.25 ORY38810.1 - 0.13 12.2 11.9 0.26 11.2 11.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY38810.1 - 0.16 11.9 15.9 0.045 13.6 12.3 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 ORY38810.1 - 0.52 10.2 11.5 1.1 9.2 11.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY38810.1 - 5.1 7.1 11.1 9.9 6.2 11.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Met_synt_B12 PF02965.17 ORY38811.1 - 1.1e-115 385.8 0.1 2e-115 385.0 0.1 1.4 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 ORY38811.1 - 8.1e-76 255.4 0.0 1.5e-75 254.5 0.0 1.5 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 ORY38811.1 - 1.2e-54 185.6 0.8 2.7e-54 184.4 0.4 1.9 2 0 0 2 2 2 1 Pterin binding enzyme B12-binding_2 PF02607.17 ORY38811.1 - 3.2e-23 82.0 0.0 1.5e-22 79.8 0.0 2.3 1 0 0 1 1 1 1 B12 binding domain B12-binding PF02310.19 ORY38811.1 - 4.4e-19 68.7 2.8 1.8e-18 66.8 0.9 3.0 3 1 1 4 4 4 1 B12 binding domain MtrH PF02007.18 ORY38811.1 - 0.00014 21.1 0.4 0.00035 19.8 0.4 1.6 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase MtrH subunit Pkinase PF00069.25 ORY38812.1 - 1.4e-74 250.9 0.0 1.8e-74 250.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY38812.1 - 9.4e-37 126.7 0.0 1.3e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 ORY38812.1 - 1.8e-11 44.6 1.8 7.8e-11 42.5 1.0 2.2 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 ORY38812.1 - 1.9e-06 27.1 0.1 2.9e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORY38812.1 - 3.2e-06 26.7 0.0 1.1e-05 24.9 0.0 1.8 1 1 1 2 2 2 1 Kinase-like C2 PF00168.30 ORY38812.1 - 0.00026 21.3 0.0 0.00061 20.0 0.0 1.7 1 1 0 1 1 1 1 C2 domain FTA2 PF13095.6 ORY38812.1 - 0.00061 19.5 0.0 0.24 11.0 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 ORY38812.1 - 0.049 13.6 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 ORY38812.1 - 0.15 11.4 0.0 0.34 10.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-CCCH PF00642.24 ORY38813.1 - 1.4e-17 63.2 18.2 2.2e-10 40.2 6.5 2.2 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 ORY38813.1 - 1.3e-08 34.4 14.7 3.3e-05 23.5 1.9 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ORY38813.1 - 1.4e-05 25.0 15.2 0.00014 21.8 1.5 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 ORY38813.1 - 0.028 15.1 11.4 0.68 10.7 1.2 2.1 1 1 1 2 2 2 0 Torus domain zf-CCCH_2 PF14608.6 ORY38813.1 - 0.56 10.8 0.6 0.56 10.8 0.6 2.8 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCHH PF10283.9 ORY38813.1 - 4.5 7.4 14.3 2.2 8.4 1.6 2.9 3 0 0 3 3 3 0 PBZ domain ADH_zinc_N PF00107.26 ORY38814.1 - 9.2e-27 93.6 0.2 1.7e-26 92.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY38814.1 - 5.5e-21 76.0 0.2 1.5e-20 74.6 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY38814.1 - 4.5e-12 45.8 0.0 2e-11 43.7 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain NMO PF03060.15 ORY38814.1 - 0.0004 19.9 0.3 0.00056 19.4 0.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase PA PF02225.22 ORY38814.1 - 0.0047 16.9 0.5 0.02 14.9 0.5 2.1 1 1 0 1 1 1 1 PA domain CMAS PF02353.20 ORY38814.1 - 0.009 15.3 0.1 0.016 14.5 0.1 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase ADH_N_2 PF16884.5 ORY38814.1 - 0.032 14.1 0.0 0.089 12.7 0.0 1.8 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase TrkA_N PF02254.18 ORY38814.1 - 0.049 13.9 0.3 0.078 13.2 0.3 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF3318 PF11780.8 ORY38814.1 - 0.14 12.1 0.5 0.25 11.3 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) SpoIIID PF12116.8 ORY38815.1 - 0.016 15.3 0.1 0.18 11.9 0.1 2.4 1 1 1 2 2 2 0 Stage III sporulation protein D ICMT PF04140.14 ORY38816.1 - 1.7e-08 34.7 0.0 1.4e-07 31.8 0.0 2.2 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 ORY38816.1 - 0.0035 17.7 0.0 0.012 16.0 0.0 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase FA_desaturase PF00487.24 ORY38817.1 - 3.7e-22 79.4 21.6 6.4e-22 78.6 21.6 1.4 1 0 0 1 1 1 1 Fatty acid desaturase F-box-like PF12937.7 ORY38818.1 - 0.0019 18.0 0.1 0.006 16.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like Glyco_trans_1_2 PF13524.6 ORY38819.1 - 3.2e-05 24.2 0.3 6.6e-05 23.2 0.3 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 ATP-cone PF03477.16 ORY38819.1 - 0.011 16.3 0.2 0.024 15.2 0.2 1.5 1 0 0 1 1 1 0 ATP cone domain TP6A_N PF04406.14 ORY38819.1 - 0.06 13.3 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Type IIB DNA topoisomerase DSPc PF00782.20 ORY38820.1 - 6.1e-12 45.5 0.0 1.2e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 ORY38820.1 - 1.9e-08 34.6 0.1 7.2e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 ORY38820.1 - 2.7e-06 27.1 0.0 5.4e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 ORY38820.1 - 0.0029 17.3 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 ORY38820.1 - 0.02 14.9 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family DnaJ PF00226.31 ORY38821.1 - 1.8e-10 40.8 0.4 7.6e-10 38.8 0.2 2.2 2 1 0 2 2 2 1 DnaJ domain GTP_cyclohydro2 PF00925.20 ORY38825.1 - 3.7e-55 185.9 0.0 1.9e-53 180.4 0.0 2.1 1 1 0 1 1 1 1 GTP cyclohydrolase II SBP_bac_8 PF13416.6 ORY38827.1 - 7e-14 52.3 2.2 3.2e-13 50.1 2.2 2.0 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 ORY38827.1 - 1.2e-11 45.2 2.0 4.5e-05 23.6 0.2 2.3 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein Thioredoxin PF00085.20 ORY38828.1 - 0.00012 22.0 0.0 0.00026 20.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin YajC PF02699.15 ORY38829.1 - 0.86 9.5 3.4 0.72 9.8 0.4 2.4 2 1 1 3 3 3 0 Preprotein translocase subunit Pkinase PF00069.25 ORY38830.1 - 1.5e-66 224.5 0.0 1.7e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY38830.1 - 8.8e-39 133.3 0.0 1.1e-38 133.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY38830.1 - 1.4e-07 31.1 0.0 9.1e-07 28.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORY38830.1 - 0.0034 17.3 0.1 0.023 14.6 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORY38830.1 - 0.0052 16.4 0.1 0.011 15.4 0.1 1.4 1 1 0 1 1 1 1 RIO1 family Pkinase PF00069.25 ORY38831.1 - 3.1e-58 197.2 0.0 2.2e-56 191.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY38831.1 - 1.6e-33 116.1 0.0 9.1e-31 107.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 ORY38831.1 - 3.6e-11 42.7 0.0 7.1e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 ORY38831.1 - 0.0027 17.1 0.7 0.25 10.6 0.1 2.6 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 ORY38831.1 - 0.049 13.0 0.0 0.3 10.4 0.0 2.0 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Patatin PF01734.22 ORY38833.1 - 0.054 13.7 0.3 0.054 13.7 0.3 1.1 1 0 0 1 1 1 0 Patatin-like phospholipase Plasmid_stab_B PF10784.9 ORY38834.1 - 0.0024 17.7 0.0 0.057 13.3 0.0 2.2 2 0 0 2 2 2 1 Plasmid stability protein Ada3 PF10198.9 ORY38834.1 - 0.0037 17.4 0.9 0.0053 16.9 0.9 1.2 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 CPG4 PF15481.6 ORY38837.1 - 0.018 15.7 2.0 0.024 15.2 2.0 1.2 1 0 0 1 1 1 0 Chondroitin proteoglycan 4 NUDIX PF00293.28 ORY38838.1 - 1.9e-09 37.7 0.0 2.3e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain GCP_C_terminal PF04130.13 ORY38839.1 - 4e-05 23.2 0.0 4.2e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 ORY38840.1 - 3.4e-82 276.5 0.0 5.7e-82 275.8 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 ORY38840.1 - 1e-68 232.1 3.0 1e-68 232.1 3.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal MAPKK1_Int PF08923.10 ORY38841.1 - 6.3e-20 71.2 0.1 7.3e-20 71.0 0.1 1.1 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting TFIIS_C PF01096.18 ORY38842.1 - 5.4e-16 58.2 1.5 5.4e-16 58.2 1.5 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 ORY38842.1 - 2.4e-06 27.3 10.8 3e-06 27.0 1.9 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit zf-ribbon_3 PF13248.6 ORY38842.1 - 0.00071 18.9 7.0 0.24 10.9 0.1 3.4 3 0 0 3 3 3 2 zinc-ribbon domain Baculo_LEF5_C PF11792.8 ORY38842.1 - 0.0075 15.9 0.0 0.0075 15.9 0.0 3.0 3 0 0 3 3 3 1 Baculoviridae late expression factor 5 C-terminal domain DZR PF12773.7 ORY38842.1 - 0.0079 16.2 9.4 0.66 10.0 9.4 2.7 1 1 0 1 1 1 1 Double zinc ribbon Zn_ribbon_recom PF13408.6 ORY38842.1 - 0.028 14.9 0.7 7 7.3 0.0 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF2387 PF09526.10 ORY38842.1 - 0.031 14.4 0.6 0.031 14.4 0.6 2.1 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) Lar_restr_allev PF14354.6 ORY38842.1 - 0.041 14.3 8.1 0.2 12.0 0.9 2.9 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-C4_Topoisom PF01396.19 ORY38842.1 - 0.072 12.9 7.7 1.6 8.6 3.4 3.0 2 1 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zinc_ribbon_9 PF14369.6 ORY38842.1 - 0.11 12.8 3.5 6.6 7.1 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon TF_Zn_Ribbon PF08271.12 ORY38842.1 - 0.6 9.7 14.6 2.8 7.5 3.9 3.1 2 2 0 2 2 2 0 TFIIB zinc-binding A2L_zn_ribbon PF08792.10 ORY38842.1 - 0.65 9.8 0.1 0.65 9.8 0.1 3.6 4 0 0 4 4 3 0 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 ORY38842.1 - 1.2 9.2 8.5 2.5 8.1 0.7 2.6 2 2 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.6 ORY38842.1 - 1.3 8.8 0.1 1.3 8.8 0.1 3.5 4 0 0 4 4 4 0 zinc-ribbon domain zf_UBZ PF18439.1 ORY38842.1 - 1.6 8.4 0.1 1.6 8.4 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger Ribosomal_S27e PF01667.17 ORY38842.1 - 2.1 8.1 14.3 3 7.6 3.3 3.5 2 2 1 3 3 3 0 Ribosomal protein S27 Ogr_Delta PF04606.12 ORY38842.1 - 2.5 8.1 8.0 0.58 10.2 0.2 2.8 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger zf-TFIIB PF13453.6 ORY38842.1 - 3.5 7.0 9.1 0.44 9.9 0.9 2.3 2 0 0 2 2 2 0 Transcription factor zinc-finger Zn-ribbon_8 PF09723.10 ORY38842.1 - 3.6 7.8 13.1 7.3 6.8 0.1 3.6 4 0 0 4 4 3 0 Zinc ribbon domain VP_N-CPKC PF11475.8 ORY38842.1 - 4 7.4 10.0 9.1 6.3 0.1 3.1 3 0 0 3 3 3 0 Virion protein N terminal domain GTP_EFTU PF00009.27 ORY38843.1 - 3.3e-34 118.1 0.6 1e-33 116.5 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 ORY38843.1 - 1.5e-18 66.8 0.0 4.3e-18 65.4 0.0 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 ORY38843.1 - 3.8e-15 56.0 8.3 1.5e-10 41.3 0.1 5.0 4 0 0 4 4 4 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 ORY38843.1 - 2.8e-09 36.8 0.5 1.2e-08 34.7 0.1 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 ORY38843.1 - 0.00015 21.8 0.0 0.00015 21.8 0.0 3.7 4 0 0 4 4 4 1 50S ribosome-binding GTPase Cwf_Cwc_15 PF04889.12 ORY38843.1 - 0.0015 18.3 21.5 0.0015 18.3 21.5 5.8 2 1 3 5 5 5 1 Cwf15/Cwc15 cell cycle control protein ATP_bind_1 PF03029.17 ORY38843.1 - 0.0023 17.8 0.0 0.0063 16.3 0.0 1.8 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Roc PF08477.13 ORY38843.1 - 0.017 15.3 0.0 0.044 14.0 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SNO PF01174.19 ORY38844.1 - 3.3e-50 170.5 0.0 3.9e-50 170.3 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 ORY38844.1 - 7.7e-15 55.0 0.2 6.8e-14 51.9 0.2 1.9 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 ORY38844.1 - 5e-06 26.3 0.0 7e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family S51 GATase PF00117.28 ORY38844.1 - 0.00031 20.6 0.1 0.0018 18.1 0.1 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORY38844.1 - 0.0011 18.8 0.2 0.014 15.2 0.0 2.4 2 1 0 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.24 ORY38844.1 - 0.0016 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family ThrE PF06738.12 ORY38845.1 - 4.6e-51 173.5 20.2 1.2e-48 165.6 3.4 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORY38845.1 - 1.1e-06 28.8 11.3 1.1e-06 28.8 11.3 2.4 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE Abhydrolase_9_N PF15420.6 ORY38845.1 - 0.033 14.2 2.9 0.059 13.4 1.2 2.2 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus FTR1 PF03239.14 ORY38846.1 - 6.9e-50 170.0 1.2 1.3e-37 129.7 0.1 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family RTA1 PF04479.13 ORY38846.1 - 0.015 15.0 2.0 0.051 13.2 0.2 2.2 2 0 0 2 2 2 0 RTA1 like protein DUF3180 PF11377.8 ORY38846.1 - 0.094 12.9 20.0 0.99 9.5 7.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) DUF4131 PF13567.6 ORY38846.1 - 0.099 12.3 4.9 2.2 7.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Wzy_C PF04932.15 ORY38846.1 - 0.16 11.6 4.9 2.2 7.9 0.0 2.6 2 1 0 2 2 2 0 O-Antigen ligase Tmemb_14 PF03647.13 ORY38846.1 - 0.18 12.6 8.5 0.9 10.3 0.9 2.5 2 0 0 2 2 2 0 Transmembrane proteins 14C DUF2721 PF11026.8 ORY38846.1 - 0.47 10.4 8.0 0.15 11.9 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF1043 PF06295.12 ORY38846.1 - 0.63 10.1 2.8 6.2 6.8 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) LptF_LptG PF03739.14 ORY38846.1 - 1.1 8.0 8.9 0.32 9.8 2.1 2.5 2 0 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG DUF3054 PF11255.8 ORY38846.1 - 6.6 7.3 14.1 2.3 8.8 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3054) DUF4201 PF13870.6 ORY38847.1 - 5.9e-44 149.9 25.6 5.9e-44 149.9 25.6 3.2 1 1 2 3 3 3 1 Domain of unknown function (DUF4201) COG5 PF10392.9 ORY38847.1 - 2.3 8.4 13.0 0.53 10.5 3.0 2.9 3 1 0 3 3 3 0 Golgi transport complex subunit 5 TFIIS_C PF01096.18 ORY38849.1 - 6.7e-11 41.9 9.9 1e-08 34.9 4.5 2.3 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) Ogr_Delta PF04606.12 ORY38849.1 - 0.00034 20.5 11.6 0.00061 19.7 2.5 2.5 2 1 0 2 2 2 2 Ogr/Delta-like zinc finger Lar_restr_allev PF14354.6 ORY38849.1 - 0.0056 17.0 1.5 0.0056 17.0 1.5 2.1 2 0 0 2 2 2 1 Restriction alleviation protein Lar RbpA PF13397.6 ORY38849.1 - 0.031 14.9 0.5 0.054 14.1 0.3 1.5 1 1 0 1 1 1 0 RNA polymerase-binding protein DpnI PF06044.12 ORY38849.1 - 0.19 11.3 5.1 0.31 10.6 0.2 2.0 1 1 1 2 2 2 0 Dam-replacing family HypA PF01155.19 ORY38849.1 - 0.28 11.2 8.2 0.031 14.3 2.1 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RNA_POL_M_15KD PF02150.16 ORY38849.1 - 0.3 11.0 0.2 0.3 11.0 0.2 2.7 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit NOB1_Zn_bind PF08772.11 ORY38849.1 - 1.3 9.2 8.8 6.8 6.9 0.6 2.6 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Zn_Tnp_IS1595 PF12760.7 ORY38849.1 - 1.8 8.6 10.8 1.9 8.6 2.9 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.12 ORY38849.1 - 5 6.7 8.5 8.2 6.0 2.2 2.6 2 1 0 2 2 2 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 ORY38849.1 - 5.1 7.3 14.3 1.6e+02 2.5 9.0 3.3 2 1 0 2 2 2 0 Zinc ribbon domain GST_C_2 PF13410.6 ORY38850.1 - 1.9e-06 27.8 0.1 4.4e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY38850.1 - 0.00023 21.3 0.3 0.0021 18.3 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 ORY38850.1 - 0.003 17.3 0.1 0.0086 15.9 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY38850.1 - 0.0057 16.8 0.0 0.017 15.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain UL41A PF17591.2 ORY38850.1 - 0.069 13.3 0.2 0.16 12.1 0.2 1.5 1 0 0 1 1 1 0 Herpesvirus UL41A Ank_2 PF12796.7 ORY38851.1 - 3.4e-14 53.2 1.1 4.1e-06 27.3 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY38851.1 - 3.7e-09 36.1 2.4 0.68 10.7 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 ORY38851.1 - 4.2e-09 36.8 0.8 8.1e-05 23.1 0.0 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY38851.1 - 1.3e-06 28.6 5.7 0.026 15.0 0.1 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 ORY38851.1 - 1.8e-05 24.9 4.9 0.016 15.5 0.1 4.3 3 1 2 5 5 5 3 Ankyrin repeats (many copies) KilA-N PF04383.13 ORY38851.1 - 0.00014 21.7 0.1 0.00094 19.0 0.1 2.1 1 1 0 1 1 1 1 KilA-N domain DUF1077 PF06417.12 ORY38853.1 - 3.1e-45 153.0 1.3 3.8e-45 152.7 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) MIX PF18529.1 ORY38853.1 - 0.0066 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial membrane-anchored proteins ABA_GPCR PF12430.8 ORY38853.1 - 0.027 14.3 0.3 0.032 14.0 0.3 1.2 1 0 0 1 1 1 0 Abscisic acid G-protein coupled receptor DUF4271 PF14093.6 ORY38853.1 - 0.04 13.8 1.4 0.1 12.5 1.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) Myb_DNA-binding PF00249.31 ORY38854.1 - 9.5e-10 38.5 0.0 2.3e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY38854.1 - 3.3e-05 24.0 0.0 9.1e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 ORY38854.1 - 7.2e-05 22.5 1.2 0.00016 21.4 1.2 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 ORY38854.1 - 0.00053 20.3 0.5 0.0018 18.6 0.0 2.1 2 0 0 2 2 2 1 SWIRM domain HTH_ParB PF17762.1 ORY38854.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 HTH domain found in ParB protein DND1_DSRM PF14709.7 ORY38854.1 - 0.15 12.3 0.1 0.32 11.3 0.1 1.5 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Mannosyl_trans3 PF11051.8 ORY38855.1 - 2.3e-26 92.8 0.0 2.4e-25 89.4 0.0 2.2 1 1 0 1 1 1 1 Mannosyltransferase putative SMC_Nse1 PF07574.13 ORY38856.1 - 1e-12 48.3 6.1 1e-06 28.8 0.6 2.6 2 1 1 3 3 3 2 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 ORY38856.1 - 3.4e-06 27.2 8.6 6.8e-06 26.3 8.6 1.5 1 0 0 1 1 1 1 RING-like domain Zn_ribbon_17 PF17120.5 ORY38856.1 - 0.27 10.9 9.7 0.51 10.0 9.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-HC5HC2H PF13771.6 ORY38856.1 - 0.96 9.7 6.8 0.52 10.6 4.1 1.9 1 1 0 1 1 1 0 PHD-like zinc-binding domain TPR_MLP1_2 PF07926.12 ORY38857.1 - 0.002 18.2 5.6 0.002 18.2 5.6 7.3 4 3 3 7 7 7 2 TPR/MLP1/MLP2-like protein OmpH PF03938.14 ORY38857.1 - 0.0029 18.0 7.4 0.0029 18.0 7.4 7.3 2 2 6 8 8 8 2 Outer membrane protein (OmpH-like) Inhibitor_I34 PF10466.9 ORY38857.1 - 0.076 13.6 0.5 0.076 13.6 0.5 3.4 5 0 0 5 5 5 0 Saccharopepsin inhibitor I34 Arc_C PF18162.1 ORY38858.1 - 0.13 12.2 1.7 0.75 9.7 0.2 2.6 2 1 1 3 3 3 0 Arc C-lobe SepF PF04472.12 ORY38859.1 - 0.21 11.9 3.4 0.48 10.7 0.0 3.2 4 1 1 5 5 5 0 Cell division protein SepF IQ PF00612.27 ORY38859.1 - 0.21 11.5 3.2 0.67 9.9 3.2 1.9 1 0 0 1 1 1 0 IQ calmodulin-binding motif Spc7 PF08317.11 ORY38859.1 - 7.7 5.3 53.7 0.093 11.6 21.8 3.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Cullin PF00888.22 ORY38860.1 - 0.00024 19.9 0.0 0.00028 19.7 0.0 1.0 1 0 0 1 1 1 1 Cullin family Cullin_binding PF03556.15 ORY38860.1 - 0.076 13.5 0.0 0.093 13.2 0.0 1.2 1 0 0 1 1 1 0 Cullin binding FAD_binding_3 PF01494.19 ORY38861.1 - 0.015 14.5 0.3 0.02 14.2 0.0 1.3 2 0 0 2 2 2 0 FAD binding domain Importin_rep PF18773.1 ORY38862.1 - 0.45 10.2 1.5 0.55 10.0 0.3 1.7 2 0 0 2 2 2 0 Importin 13 repeat Glyco_hydro_48 PF02011.15 ORY38863.1 - 0.0088 14.6 0.0 0.013 14.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 48 PPV_E1_N PF00524.18 ORY38863.1 - 0.11 13.0 1.9 1.7 9.1 0.0 2.6 2 0 0 2 2 2 0 E1 Protein, N terminal domain CENP-T_C PF15511.6 ORY38863.1 - 0.14 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold AA_permease PF00324.21 ORY38866.1 - 2.7e-111 372.5 34.8 3.3e-111 372.2 34.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY38866.1 - 3.2e-42 144.9 41.0 3.8e-42 144.6 41.0 1.0 1 0 0 1 1 1 1 Amino acid permease Pkinase PF00069.25 ORY38867.1 - 5.7e-35 120.9 0.9 1.7e-32 112.9 0.0 3.2 2 2 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY38867.1 - 1.1e-17 64.2 0.2 4.2e-17 62.3 0.0 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY38867.1 - 0.00017 21.0 0.0 0.00017 21.0 0.0 2.3 3 0 0 3 3 3 1 Kinase-like APH PF01636.23 ORY38867.1 - 0.1 12.5 0.2 0.25 11.2 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Meckelin PF09773.9 ORY38867.1 - 8.9 4.3 9.6 15 3.5 9.6 1.2 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) Viral_P18 PF04521.13 ORY38868.1 - 0.077 12.8 1.1 0.11 12.3 1.1 1.3 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein MBD PF01429.19 ORY38869.1 - 0.00071 19.2 0.1 0.0014 18.3 0.1 1.7 1 1 0 1 1 1 1 Methyl-CpG binding domain Csm1 PF12539.8 ORY38870.1 - 1.2e-07 32.2 0.0 2.4e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 TelA PF05816.11 ORY38870.1 - 0.003 16.7 4.5 0.0045 16.1 4.5 1.2 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) BLOC1_2 PF10046.9 ORY38870.1 - 0.011 16.1 4.7 0.024 14.9 4.2 1.9 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sec34 PF04136.15 ORY38870.1 - 0.019 14.8 1.2 0.033 14.1 1.2 1.4 1 0 0 1 1 1 0 Sec34-like family TRAF_BIRC3_bd PF16673.5 ORY38870.1 - 0.029 14.1 2.3 0.029 14.1 2.3 2.6 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Laminin_II PF06009.12 ORY38870.1 - 0.038 14.0 2.2 0.079 13.0 2.2 1.5 1 0 0 1 1 1 0 Laminin Domain II MbeD_MobD PF04899.12 ORY38870.1 - 0.05 13.7 0.5 0.05 13.7 0.5 2.0 2 1 0 2 2 2 0 MbeD/MobD like TMPIT PF07851.13 ORY38870.1 - 0.1 11.9 4.4 0.15 11.3 4.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF5094 PF17015.5 ORY38870.1 - 0.11 12.6 0.0 0.11 12.6 0.0 2.9 2 1 0 3 3 3 0 Domain of unknown function (DUF5094) SesA PF17107.5 ORY38870.1 - 0.18 12.0 3.9 0.15 12.3 2.2 1.8 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF1664 PF07889.12 ORY38870.1 - 0.19 11.8 5.5 0.082 12.9 2.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) BRE1 PF08647.11 ORY38870.1 - 0.19 11.8 11.8 0.42 10.7 11.8 1.6 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase HALZ PF02183.18 ORY38870.1 - 0.63 10.3 11.4 1.7 8.9 1.5 3.3 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF4238 PF14022.6 ORY38870.1 - 0.91 9.0 7.0 1.1 8.7 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) Spc7 PF08317.11 ORY38870.1 - 1.1 8.1 19.7 4.5 6.1 19.7 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein LMBR1 PF04791.16 ORY38870.1 - 1.2 7.9 4.7 1.4 7.8 4.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein YlqD PF11068.8 ORY38870.1 - 1.3 9.4 11.7 0.17 12.3 6.4 2.0 1 1 1 2 2 2 0 YlqD protein FUSC PF04632.12 ORY38870.1 - 2.4 6.6 3.7 3 6.2 3.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family bZIP_1 PF00170.21 ORY38870.1 - 5.2 7.3 11.7 6.4 7.0 4.6 3.0 1 1 1 2 2 2 0 bZIP transcription factor MCU PF04678.13 ORY38870.1 - 9.3 6.3 11.6 16 5.5 5.6 2.4 1 1 1 2 2 2 0 Mitochondrial calcium uniporter NST1 PF13945.6 ORY38871.1 - 5.5e-48 163.6 14.9 5.5e-48 163.6 14.9 4.6 4 1 1 5 5 5 1 Salt tolerance down-regulator PBP1_TM PF14812.6 ORY38871.1 - 0.018 15.4 3.6 0.018 15.4 3.6 6.2 7 1 0 7 7 7 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pol_alpha_B_N PF08418.10 ORY38873.1 - 5 7.0 5.9 5.8 6.8 5.9 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal PAP1 PF08601.10 ORY38873.1 - 8.3 6.0 13.4 9.7 5.8 13.4 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 CFEM PF05730.11 ORY38874.1 - 0.0028 17.7 0.9 0.0037 17.3 0.2 1.5 2 0 0 2 2 2 1 CFEM domain PfkB PF00294.24 ORY38876.1 - 4.2e-69 233.2 0.1 4.8e-69 233.0 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 ORY38876.1 - 0.016 14.6 0.0 0.037 13.4 0.0 1.5 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase DUF3112 PF11309.8 ORY38877.1 - 0.048 13.1 2.6 0.13 11.7 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) Sec7 PF01369.20 ORY38878.1 - 4.4e-66 222.1 0.0 8.6e-66 221.1 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 ORY38878.1 - 5.9e-11 42.5 0.9 5.5e-09 36.1 0.0 3.1 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF3439 PF11921.8 ORY38878.1 - 2 8.4 5.6 4.5 7.3 5.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) AAA_6 PF12774.7 ORY38879.1 - 4.8e-162 538.5 0.6 4.2e-159 528.8 0.0 3.9 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 ORY38879.1 - 3e-139 464.5 4.3 3e-139 464.5 4.3 3.3 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 ORY38879.1 - 2.4e-105 351.6 0.0 7.8e-105 349.9 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 ORY38879.1 - 2e-104 349.1 0.0 5.4e-100 334.6 0.0 3.6 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 ORY38879.1 - 1.5e-94 315.2 2.4 1.5e-94 315.2 2.4 2.9 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 ORY38879.1 - 9.5e-77 256.6 0.0 1.7e-70 236.2 0.0 4.0 4 0 0 4 4 4 3 P-loop containing dynein motor region AAA_lid_11 PF18198.1 ORY38879.1 - 6.4e-56 188.7 0.1 3.4e-55 186.3 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 ORY38879.1 - 3.4e-52 177.6 12.6 3.4e-52 177.6 12.6 1.7 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 ORY38879.1 - 4.4e-40 136.5 0.0 1.1e-38 132.0 0.0 3.1 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 ORY38879.1 - 1.2e-28 99.7 0.1 1.2e-27 96.5 0.0 3.0 3 0 0 3 3 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 ORY38879.1 - 2.1e-18 66.7 0.0 0.00021 21.3 0.0 5.7 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 ORY38879.1 - 1.6e-16 60.3 0.1 8.4e-16 58.0 0.1 2.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 ORY38879.1 - 4.6e-10 40.1 0.0 0.12 12.8 0.0 5.9 5 0 0 5 5 5 2 AAA ATPase domain AAA PF00004.29 ORY38879.1 - 5.5e-09 36.5 0.2 0.047 14.1 0.0 5.2 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 ORY38879.1 - 1.3e-05 25.8 0.0 0.065 13.8 0.0 4.0 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 ORY38879.1 - 4.8e-05 22.6 0.0 0.17 10.9 0.0 3.6 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_22 PF13401.6 ORY38879.1 - 8e-05 22.9 5.6 2.3 8.5 0.0 5.9 7 0 0 7 7 4 1 AAA domain RNA_helicase PF00910.22 ORY38879.1 - 0.00018 21.8 0.1 4.9 7.6 0.0 3.9 3 0 0 3 3 3 1 RNA helicase ABC_tran PF00005.27 ORY38879.1 - 0.00063 20.3 0.1 12 6.4 0.0 4.3 4 0 0 4 4 3 0 ABC transporter AAA_30 PF13604.6 ORY38879.1 - 0.0022 17.8 0.2 0.85 9.3 0.1 3.6 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 ORY38879.1 - 0.0033 17.1 0.3 2.5 7.9 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain Spc7 PF08317.11 ORY38879.1 - 0.013 14.4 23.9 0.0033 16.4 3.1 3.6 4 0 0 4 4 3 0 Spc7 kinetochore protein RsgA_GTPase PF03193.16 ORY38879.1 - 0.02 14.8 0.0 3.9 7.3 0.0 3.8 4 0 0 4 4 3 0 RsgA GTPase AAA_28 PF13521.6 ORY38879.1 - 0.024 14.9 0.2 54 4.0 0.0 3.9 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 ORY38879.1 - 0.035 14.3 0.3 11 6.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain FNIP_M PF14637.6 ORY38879.1 - 0.053 13.5 1.6 14 5.6 0.1 3.2 3 0 0 3 3 3 0 Folliculin-interacting protein middle domain NACHT PF05729.12 ORY38879.1 - 0.14 12.1 0.1 51 3.7 0.0 3.6 3 0 0 3 3 3 0 NACHT domain SRP54 PF00448.22 ORY38879.1 - 0.15 11.7 0.8 28 4.3 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain MADF_DNA_bdg PF10545.9 ORY38879.1 - 0.29 11.5 1.5 12 6.3 0.0 2.8 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3496 PF12001.8 ORY38879.1 - 0.71 10.3 4.7 3.2 8.2 4.7 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) TraF PF13728.6 ORY38879.1 - 8.2 6.2 10.7 0.083 12.7 1.1 2.3 2 0 0 2 2 1 0 F plasmid transfer operon protein Mod_r PF07200.13 ORY38879.1 - 8.6 6.5 17.5 0.12 12.5 5.0 3.5 3 0 0 3 3 2 0 Modifier of rudimentary (Mod(r)) protein LRR_8 PF13855.6 ORY38880.1 - 1.2e-06 28.2 17.0 0.0032 17.2 0.4 4.6 3 1 1 4 4 4 4 Leucine rich repeat Pep_deformylase PF01327.21 ORY38881.1 - 3e-27 95.2 0.0 5.2e-27 94.4 0.0 1.4 1 1 0 1 1 1 1 Polypeptide deformylase SHOCT PF09851.9 ORY38881.1 - 0.014 15.1 2.4 0.025 14.3 2.4 1.4 1 0 0 1 1 1 0 Short C-terminal domain RVT_3 PF13456.6 ORY38882.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase-like Imm52 PF15579.6 ORY38883.1 - 0.064 13.1 0.0 5.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Immunity protein 52 AAA_18 PF13238.6 ORY38883.1 - 0.068 13.7 0.0 0.33 11.5 0.0 2.1 3 0 0 3 3 3 0 AAA domain AMP-binding PF00501.28 ORY38884.1 - 1.6e-96 323.5 0.0 2e-96 323.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY38884.1 - 6.7e-18 65.4 0.5 2.3e-17 63.7 0.5 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain IucA_IucC PF04183.12 ORY38884.1 - 0.087 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 IucA / IucC family Glyco_transf_22 PF03901.17 ORY38885.1 - 7.6e-37 127.5 15.3 1.1e-36 127.0 15.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family CLTH PF10607.9 ORY38886.1 - 3e-30 105.1 0.9 5.1e-30 104.3 0.3 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 ORY38886.1 - 1.7e-07 31.2 0.5 3.4e-07 30.2 0.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY38886.1 - 2.4e-05 24.2 0.9 5e-05 23.2 0.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORY38886.1 - 0.00053 20.1 1.6 0.0013 18.9 1.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Rtf2 PF04641.12 ORY38886.1 - 0.00069 19.1 0.2 0.00069 19.1 0.2 1.8 2 0 0 2 2 2 1 Rtf2 RING-finger zf-C3HC4 PF00097.25 ORY38886.1 - 0.0032 17.3 2.3 0.007 16.2 2.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY38886.1 - 0.0053 16.6 1.1 0.01 15.7 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY38886.1 - 0.0059 16.9 1.0 0.013 15.8 1.0 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 ORY38886.1 - 0.0076 16.1 0.6 0.016 15.1 0.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 ORY38886.1 - 0.018 14.9 2.1 0.044 13.6 2.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF5358 PF17311.2 ORY38886.1 - 0.12 12.4 0.2 0.24 11.4 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5358) mRNA_cap_enzyme PF01331.19 ORY38887.1 - 2.6e-47 161.2 0.1 3.5e-47 160.8 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 ORY38887.1 - 8e-20 71.5 0.0 1.4e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 ORY38887.1 - 6.8e-09 35.7 0.1 0.00074 19.2 0.1 2.9 1 1 1 2 2 2 2 ATP dependent DNA ligase domain LtrA PF06772.11 ORY38888.1 - 6.1e-29 101.3 10.0 7e-29 101.1 10.0 1.0 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) UPF0086 PF01868.16 ORY38889.1 - 1.4e-23 82.6 0.0 2.2e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 SHIPPO-rpt PF07004.12 ORY38890.1 - 5.6e-11 42.8 31.9 1.4 10.0 2.1 11.6 11 0 0 11 11 11 7 Sperm-tail PG-rich repeat Ax_dynein_light PF10211.9 ORY38891.1 - 7.1e-88 293.5 11.5 8.2e-88 293.2 11.5 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain LRRFIP PF09738.9 ORY38891.1 - 0.0022 17.5 9.0 0.0031 17.0 9.0 1.2 1 0 0 1 1 1 1 LRRFIP family bZIP_2 PF07716.15 ORY38891.1 - 0.085 13.0 13.3 0.42 10.7 2.9 2.8 2 0 0 2 2 2 0 Basic region leucine zipper Syntaxin-6_N PF09177.11 ORY38891.1 - 0.12 12.9 8.0 0.056 14.0 5.7 1.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF4164 PF13747.6 ORY38891.1 - 0.39 11.0 11.5 2.7 8.4 6.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Jnk-SapK_ap_N PF09744.9 ORY38891.1 - 0.47 10.7 15.9 15 5.8 15.9 2.3 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 GrpE PF01025.19 ORY38891.1 - 0.69 9.6 10.0 0.77 9.4 8.6 1.8 2 0 0 2 2 2 0 GrpE TSNAXIP1_N PF15739.5 ORY38891.1 - 1.4 9.3 13.0 2.4 8.6 4.4 2.3 1 1 1 2 2 2 0 Translin-associated factor X-interacting N-terminus Spc24 PF08286.11 ORY38891.1 - 2.7 8.3 8.2 2.1 8.6 6.3 1.8 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 APG6_N PF17675.1 ORY38891.1 - 3.1 8.3 19.0 11 6.6 19.4 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region FapA PF03961.13 ORY38891.1 - 4.1 5.9 9.1 6 5.4 8.8 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF724 PF05266.14 ORY38891.1 - 5.5 6.8 11.7 3.5 7.4 9.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF3784 PF12650.7 ORY38892.1 - 0.066 13.4 3.7 0.12 12.6 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) CoA_binding_3 PF13727.6 ORY38892.1 - 0.25 11.4 1.2 0.36 10.8 1.2 1.1 1 0 0 1 1 1 0 CoA-binding domain Phage_holin_3_6 PF07332.11 ORY38892.1 - 0.27 11.3 3.4 0.42 10.7 3.4 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III ATP-synt_Z PF16594.5 ORY38894.1 - 0.0081 15.6 0.3 0.0081 15.6 0.3 2.1 2 0 0 2 2 2 1 Putative AtpZ or ATP-synthase-associated DUF3955 PF13127.6 ORY38894.1 - 3.2 7.6 7.7 0.23 11.3 0.8 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3955) Acyl-CoA_dh_1 PF00441.24 ORY38895.1 - 9.9e-29 100.5 0.2 1.6e-28 99.8 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY38895.1 - 3.9e-20 71.9 0.0 6.4e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY38895.1 - 1.7e-11 44.5 0.0 3.1e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY38895.1 - 0.00097 19.8 0.0 0.013 16.2 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain LIDHydrolase PF10230.9 ORY38896.1 - 1.2e-49 169.2 1.2 1.7e-49 168.8 1.2 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 ORY38896.1 - 0.00016 21.0 0.0 0.00032 20.1 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 ORY38896.1 - 0.017 15.0 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase PGAP1 PF07819.13 ORY38896.1 - 0.017 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 ORY38896.1 - 0.022 15.4 0.0 0.039 14.5 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family DEAD PF00270.29 ORY38897.1 - 1.3e-46 158.6 0.0 2.2e-46 157.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY38897.1 - 4.7e-32 110.6 0.0 2.2e-31 108.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY38897.1 - 6.1e-05 23.1 0.0 0.00013 22.0 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4729 PF15866.5 ORY38898.1 - 0.00011 21.6 0.1 0.00015 21.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4729) Tox-GHH2 PF15635.6 ORY38898.1 - 0.017 15.7 0.1 0.029 14.9 0.1 1.4 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 zf-TRAF PF02176.18 ORY38898.1 - 0.059 14.1 1.3 0.086 13.5 1.3 1.2 1 0 0 1 1 1 0 TRAF-type zinc finger ETC_C1_NDUFA4 PF04800.12 ORY38899.1 - 0.0006 20.0 0.9 0.79 10.0 0.1 2.6 2 0 0 2 2 2 2 ETC complex I subunit conserved region DUF775 PF05603.12 ORY38899.1 - 0.0017 18.0 0.1 0.0034 16.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF775) VasI PF11319.8 ORY38899.1 - 0.045 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Type VI secretion system VasI, EvfG, VC_A0118 LIDHydrolase PF10230.9 ORY38900.1 - 1.7e-49 168.8 0.0 2.3e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 ORY38900.1 - 0.0018 17.6 0.0 0.0044 16.3 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY38900.1 - 0.0079 16.8 0.0 0.0091 16.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 ORY38900.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 1 0 1 1 1 0 PGAP1-like protein DUF2407_C PF13373.6 ORY38901.1 - 0.072 13.3 0.8 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 DUF2407 C-terminal domain Tox-GHH2 PF15635.6 ORY38902.1 - 0.059 13.9 0.1 0.12 12.9 0.1 1.4 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 DUF775 PF05603.12 ORY38903.1 - 0.00069 19.2 0.1 0.0014 18.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF775) ETC_C1_NDUFA4 PF04800.12 ORY38903.1 - 0.11 12.8 0.5 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 ETC complex I subunit conserved region LIDHydrolase PF10230.9 ORY38904.1 - 1.1e-44 153.0 0.8 2.1e-28 99.6 0.0 2.2 1 1 1 2 2 2 2 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 ORY38904.1 - 0.0011 18.3 0.0 0.0027 17.0 0.0 1.8 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY38904.1 - 0.029 15.0 0.0 0.034 14.7 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY38904.1 - 0.081 12.6 0.0 1.5 8.4 0.0 2.2 1 1 0 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.13 ORY38904.1 - 0.087 12.5 0.0 0.2 11.3 0.0 1.7 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.7 ORY38904.1 - 0.2 11.4 0.0 0.46 10.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Tox-GHH2 PF15635.6 ORY38906.1 - 0.058 13.9 0.1 0.12 12.9 0.1 1.4 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 DUF775 PF05603.12 ORY38907.1 - 0.0012 18.4 0.1 0.0022 17.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF775) ETC_C1_NDUFA4 PF04800.12 ORY38907.1 - 0.003 17.8 3.8 0.65 10.3 0.1 2.7 3 0 0 3 3 3 2 ETC complex I subunit conserved region VasI PF11319.8 ORY38907.1 - 0.033 13.8 0.0 0.088 12.5 0.0 1.7 1 0 0 1 1 1 0 Type VI secretion system VasI, EvfG, VC_A0118 LIDHydrolase PF10230.9 ORY38908.1 - 1e-48 166.3 0.1 2e-48 165.3 0.1 1.5 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 ORY38908.1 - 0.0085 15.4 0.0 0.018 14.3 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY38908.1 - 0.18 12.4 0.0 0.18 12.4 0.0 2.6 2 1 1 3 3 3 0 Alpha/beta hydrolase family DUF2407_C PF13373.6 ORY38908.1 - 0.25 11.5 0.4 0.74 10.0 0.0 1.9 2 0 0 2 2 2 0 DUF2407 C-terminal domain LRR_4 PF12799.7 ORY38909.1 - 5.4e-23 80.7 27.3 2e-06 28.0 0.7 5.6 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY38909.1 - 9.2e-22 76.6 29.3 8.6e-07 28.6 1.6 4.8 1 1 4 5 5 5 5 Leucine rich repeat LRR_1 PF00560.33 ORY38909.1 - 4.9e-07 29.4 36.6 0.1 13.2 0.4 9.5 9 1 0 9 9 9 4 Leucine Rich Repeat F-box-like PF12937.7 ORY38909.1 - 0.00079 19.3 0.1 0.0024 17.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 ORY38909.1 - 0.0029 17.5 34.9 1.6 9.0 1.3 8.1 8 0 0 8 8 8 4 Leucine Rich repeat F-box PF00646.33 ORY38909.1 - 0.0053 16.6 0.0 0.019 14.8 0.0 1.9 1 0 0 1 1 1 1 F-box domain SGL PF08450.12 ORY38910.1 - 6.7e-10 39.0 0.0 1e-09 38.3 0.0 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 ORY38910.1 - 4.4e-09 36.3 0.0 2.3e-07 30.8 0.0 3.1 3 0 0 3 3 3 1 Strictosidine synthase Arylesterase PF01731.20 ORY38910.1 - 2.1e-05 24.6 0.2 0.00036 20.7 0.0 2.5 2 0 0 2 2 2 1 Arylesterase WD40 PF00400.32 ORY38910.1 - 0.098 13.6 0.1 36 5.4 0.0 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat RGS PF00615.19 ORY38911.1 - 3.8e-12 46.5 0.0 1.1e-06 28.9 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain CUE PF02845.16 ORY38912.1 - 0.00042 20.0 0.0 0.00074 19.2 0.0 1.4 1 0 0 1 1 1 1 CUE domain DUF924 PF06041.11 ORY38913.1 - 0.046 13.8 0.0 0.047 13.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) FPL PF09758.9 ORY38914.1 - 3.1e-29 101.9 2.2 5.8e-29 101.0 2.2 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein AbiJ_NTD3 PF18860.1 ORY38914.1 - 0.043 13.3 0.0 13 5.3 0.0 3.2 3 0 0 3 3 3 0 AbiJ N-terminal domain 3 Ank_2 PF12796.7 ORY38915.1 - 4.3e-07 30.4 0.1 7.2e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY38915.1 - 1.5e-05 25.2 0.1 3.2e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY38915.1 - 0.00076 20.0 0.1 0.0042 17.6 0.1 2.2 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY38915.1 - 0.0013 19.0 0.2 0.026 15.1 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 ORY38915.1 - 0.0086 16.5 0.0 0.022 15.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Pkinase PF00069.25 ORY38917.1 - 1.6e-61 208.0 0.0 3.8e-61 206.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY38917.1 - 1.7e-29 102.9 0.0 2.8e-18 66.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY38917.1 - 0.00018 21.0 0.0 0.097 12.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 ORY38917.1 - 0.0013 18.7 0.0 0.12 12.2 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY38917.1 - 0.0021 16.9 0.0 0.0032 16.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORY38917.1 - 0.02 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY38917.1 - 0.033 13.1 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain E1_DerP2_DerF2 PF02221.15 ORY38918.1 - 6.2e-17 62.3 0.0 7.9e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 ORY38918.1 - 0.00056 20.3 0.0 0.0025 18.2 0.0 1.9 2 0 0 2 2 2 1 ML-like domain Alph_Pro_TM PF09608.10 ORY38918.1 - 0.024 14.5 0.0 0.29 10.9 0.0 2.1 2 0 0 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) Glyco_hydro_61 PF03443.14 ORY38918.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 DUF2738 PF10927.8 ORY38919.1 - 0.061 12.4 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) FAM178 PF14816.6 ORY38919.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 Ank_2 PF12796.7 ORY38922.1 - 3.3e-29 101.3 2.2 8e-11 42.4 0.0 3.4 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY38922.1 - 2.4e-24 85.3 5.2 7e-07 29.7 0.2 6.8 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY38922.1 - 1.2e-18 65.3 3.5 0.011 16.2 0.1 6.3 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 ORY38922.1 - 7.6e-18 64.1 2.7 0.00019 21.7 0.1 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 ORY38922.1 - 2.1e-14 53.4 8.8 0.00041 20.6 0.1 5.9 2 2 4 6 6 6 5 Ankyrin repeats (many copies) HET PF06985.11 ORY38923.1 - 2.2e-08 34.6 2.9 4.2e-07 30.4 2.9 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WD40_4 PF16300.5 ORY38988.1 - 4.6e-25 87.2 0.2 7.6e-14 51.3 0.0 2.6 2 0 0 2 2 2 2 Type of WD40 repeat WD40 PF00400.32 ORY38988.1 - 1.8e-06 28.5 3.9 0.0002 22.1 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY38988.1 - 3.9e-05 23.9 0.0 0.059 13.7 0.0 2.9 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1899 PF08953.11 ORY38988.1 - 0.004 17.0 0.1 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) Ge1_WD40 PF16529.5 ORY38988.1 - 0.014 14.3 0.0 0.14 11.1 0.0 2.2 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 ORY38988.1 - 0.11 10.8 0.0 7 4.8 0.0 2.6 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz GGACT PF06094.12 ORY38989.1 - 7.5e-07 29.8 0.0 1.1e-06 29.3 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like ChaC PF04752.12 ORY38989.1 - 0.069 13.2 0.0 0.19 11.7 0.0 1.7 1 1 0 1 1 1 0 ChaC-like protein Herpes_UL35 PF04496.12 ORY38990.1 - 0.056 13.7 0.0 1.8 8.9 0.0 2.7 3 0 0 3 3 3 0 Herpesvirus UL35 family Tiam_CC_Ex PF18385.1 ORY38990.1 - 0.15 12.4 0.0 0.62 10.5 0.0 2.0 2 0 0 2 2 2 0 T-lymphoma invasion and metastasis CC-Ex domain Ank_2 PF12796.7 ORY38991.1 - 4.4e-06 27.2 0.0 1.3e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY38991.1 - 8.5e-05 22.7 0.0 1.4 9.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat MMR_HSR1 PF01926.23 ORY38991.1 - 8.7e-05 22.6 0.9 0.00072 19.6 0.2 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.18 ORY38991.1 - 0.001 18.4 0.3 1.3 8.3 0.1 2.7 2 0 0 2 2 2 2 Septin Ank_4 PF13637.6 ORY38991.1 - 0.0015 19.1 0.0 0.0076 16.8 0.0 2.3 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY38991.1 - 0.003 17.8 0.0 0.21 11.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) AIG1 PF04548.16 ORY38991.1 - 0.012 14.9 0.3 0.21 10.9 0.0 2.5 2 0 0 2 2 2 0 AIG1 family Ank PF00023.30 ORY38991.1 - 0.1 13.1 0.1 0.91 10.1 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeat HMMR_N PF15905.5 ORY38991.1 - 0.68 9.3 7.3 0.67 9.4 1.5 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal PMT PF02366.18 ORY38992.1 - 8e-84 281.0 13.9 8e-84 281.0 13.9 1.9 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORY38992.1 - 3.1e-58 196.7 14.2 3.1e-58 196.7 14.2 2.5 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORY38992.1 - 5.2e-12 46.0 0.0 8.3e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 MIR domain VIT1 PF01988.19 ORY38994.1 - 7.6e-07 29.2 0.2 8.6e-07 29.0 0.2 1.1 1 0 0 1 1 1 1 VIT family DUF4381 PF14316.6 ORY38995.1 - 0.12 12.6 0.2 0.23 11.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Vps39_2 PF10367.9 ORY38997.1 - 0.049 14.1 0.2 0.084 13.3 0.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Retrotran_gag_2 PF14223.6 ORY38998.1 - 0.00096 18.8 0.1 0.0012 18.5 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type WAK PF08488.11 ORY38998.1 - 0.014 15.9 0.0 0.019 15.5 0.0 1.3 1 0 0 1 1 1 0 Wall-associated kinase Bax1-I PF01027.20 ORY38999.1 - 2.4e-18 66.8 2.6 3.4e-18 66.2 2.6 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 SAP PF02037.27 ORY39001.1 - 0.036 13.8 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 SAP domain Bax1-I PF01027.20 ORY39002.1 - 8e-40 136.9 11.5 1.1e-39 136.4 11.5 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 EB PF01683.18 ORY39003.1 - 0.041 14.2 4.0 0.098 13.0 4.0 1.7 1 1 0 1 1 1 0 EB module TNFR_c6 PF00020.18 ORY39003.1 - 3.9 8.0 7.7 0.75 10.2 0.9 2.6 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region LRR_8 PF13855.6 ORY39004.1 - 9.2e-05 22.1 5.8 0.002 17.8 0.1 3.1 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY39004.1 - 0.00041 20.7 2.7 0.21 12.1 0.0 3.1 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY39004.1 - 1.1 10.1 5.3 1.5e+02 3.6 0.0 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat EGF_Tenascin PF18720.1 ORY39004.1 - 5.5 7.1 10.8 19 5.5 10.8 2.0 1 0 0 1 1 1 0 Tenascin EGF domain OpuAC PF04069.12 ORY39005.1 - 2.7e-10 40.3 0.7 4.6e-05 23.1 0.1 2.1 2 0 0 2 2 2 2 Substrate binding domain of ABC-type glycine betaine transport system Ephrin_rec_like PF07699.13 ORY39005.1 - 0.0022 17.7 2.2 0.0022 17.7 2.2 3.5 3 0 0 3 3 3 1 Putative ephrin-receptor like NCD3G PF07562.14 ORY39005.1 - 0.0071 16.3 8.5 0.024 14.6 1.2 2.7 2 0 0 2 2 2 2 Nine Cysteines Domain of family 3 GPCR Dioxygenase_C PF00775.21 ORY39005.1 - 0.068 12.6 0.1 0.55 9.6 0.0 2.1 2 0 0 2 2 2 0 Dioxygenase DUF4083 PF13314.6 ORY39005.1 - 0.07 13.1 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) PIG-F PF06699.11 ORY39006.1 - 1.5e-28 100.2 8.3 1.6e-28 100.1 8.3 1.0 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF1461 PF07314.11 ORY39006.1 - 0.024 14.5 1.2 0.044 13.7 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Gly-zipper_YMGG PF13441.6 ORY39006.1 - 0.11 12.3 3.3 10 6.0 2.4 2.2 2 0 0 2 2 2 0 YMGG-like Gly-zipper Ras PF00071.22 ORY39007.1 - 1.8e-47 160.9 0.0 2.1e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY39007.1 - 5.4e-29 100.9 0.1 1.4e-28 99.5 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY39007.1 - 2e-10 40.4 0.0 2.4e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 ORY39007.1 - 0.00013 22.3 0.1 0.00051 20.4 0.1 1.9 1 1 0 1 1 1 1 RNA helicase G-alpha PF00503.20 ORY39007.1 - 0.0016 17.7 0.3 0.4 9.8 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 ORY39007.1 - 0.0046 16.4 0.0 0.0058 16.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 ORY39007.1 - 0.015 14.8 0.1 0.024 14.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Pox_A32 PF04665.12 ORY39007.1 - 0.023 14.2 0.1 0.043 13.3 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 ORY39007.1 - 0.034 14.1 0.2 7.9 6.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase ArgoMid PF16487.5 ORY39007.1 - 0.038 14.2 0.1 0.069 13.4 0.1 1.5 1 0 0 1 1 1 0 Mid domain of argonaute MMR_HSR1 PF01926.23 ORY39007.1 - 0.049 13.7 0.0 0.082 13.0 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 ORY39007.1 - 0.055 13.2 0.1 0.087 12.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 ORY39007.1 - 0.083 12.9 0.1 0.19 11.7 0.2 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 ORY39007.1 - 0.095 12.9 0.2 0.17 12.1 0.2 1.4 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.9 ORY39007.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 ORY39007.1 - 0.16 12.3 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 ORY39007.1 - 0.28 10.4 1.5 0.25 10.6 0.2 1.5 2 0 0 2 2 2 0 Septin Exo70 PF03081.15 ORY39008.1 - 1.4e-63 215.2 7.0 1.4e-63 215.2 7.0 2.6 1 1 1 2 2 2 1 Exo70 exocyst complex subunit V-SNARE PF05008.15 ORY39008.1 - 0.021 15.2 5.1 0.8 10.1 0.0 3.7 4 0 0 4 4 3 0 Vesicle transport v-SNARE protein N-terminus HrpB7 PF09486.10 ORY39008.1 - 0.029 14.7 0.6 6.7 7.1 0.3 2.6 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) BORCS7 PF16088.5 ORY39008.1 - 0.098 12.9 3.1 0.42 10.9 1.3 3.1 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 DASH_Hsk3 PF08227.11 ORY39008.1 - 0.12 12.7 2.2 4.3 7.8 0.5 3.1 3 0 0 3 3 2 0 DASH complex subunit Hsk3 like YkyA PF10368.9 ORY39008.1 - 0.14 11.8 8.3 3.2 7.4 0.5 2.8 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein CENP-Q PF13094.6 ORY39008.1 - 0.15 12.3 5.2 0.37 11.0 5.2 1.7 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Osmo_CC PF08946.10 ORY39008.1 - 0.15 12.3 3.4 0.33 11.2 0.1 3.2 3 0 0 3 3 3 0 Osmosensory transporter coiled coil THOC7 PF05615.13 ORY39008.1 - 0.23 11.7 3.0 0.68 10.2 1.1 2.4 2 0 0 2 2 2 0 Tho complex subunit 7 Sec34 PF04136.15 ORY39008.1 - 0.38 10.6 12.0 0.22 11.4 7.3 3.1 3 1 0 3 3 3 0 Sec34-like family APG17 PF04108.12 ORY39008.1 - 0.38 9.8 6.1 0.15 11.2 1.7 2.5 2 1 0 2 2 2 0 Autophagy protein Apg17 DUF4404 PF14357.6 ORY39008.1 - 0.39 11.4 3.0 3.2 8.5 0.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) BLOC1_2 PF10046.9 ORY39008.1 - 0.51 10.7 4.1 0.96 9.8 0.4 3.1 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Dynactin_p22 PF07426.11 ORY39008.1 - 2.5 7.9 13.2 0.44 10.4 2.3 4.3 4 1 0 4 4 4 0 Dynactin subunit p22 Syntaxin PF00804.25 ORY39009.1 - 1.1e-43 149.3 16.5 1.1e-43 149.3 16.5 1.4 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 ORY39009.1 - 6.6e-13 48.5 1.4 3.3e-12 46.2 1.4 2.3 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 ORY39009.1 - 4.1e-08 33.5 6.7 4.1e-08 33.5 6.7 2.7 2 1 1 3 3 3 1 Syntaxin-like protein Spore_III_AB PF09548.10 ORY39009.1 - 0.015 15.4 0.2 0.015 15.4 0.2 2.7 2 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) DUF2118 PF09891.9 ORY39009.1 - 0.056 13.4 0.6 0.32 11.0 0.6 2.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) DUF948 PF06103.11 ORY39009.1 - 0.13 12.5 9.6 0.17 12.2 1.5 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DraK_HK_N PF18092.1 ORY39009.1 - 0.15 12.5 2.3 0.74 10.3 0.1 2.3 2 0 0 2 2 2 0 DraK Histidine Kinase N-terminal domain VitD-bind_III PF09164.10 ORY39009.1 - 0.19 11.8 1.0 0.42 10.6 0.2 2.0 2 0 0 2 2 2 0 Vitamin D binding protein, domain III Baculo_PEP_C PF04513.12 ORY39009.1 - 0.3 11.1 10.2 0.19 11.8 1.6 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus 60KD_IMP PF02096.20 ORY39009.1 - 0.59 10.0 9.2 12 5.8 1.4 3.4 2 1 1 3 3 3 0 60Kd inner membrane protein DUF3708 PF12501.8 ORY39009.1 - 0.89 9.3 8.2 0.43 10.3 1.7 2.2 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter Herpes_UL25 PF01499.16 ORY39009.1 - 1 7.8 7.3 0.15 10.5 2.3 1.8 1 1 0 2 2 2 0 Herpesvirus UL25 family Allexi_40kDa PF05549.11 ORY39009.1 - 1.4 8.4 11.6 0.066 12.7 3.1 2.3 1 1 0 2 2 2 0 Allexivirus 40kDa protein YfdX PF10938.8 ORY39009.1 - 1.6 8.7 13.3 0.3 11.0 2.5 3.1 2 1 1 3 3 3 0 YfdX protein PriC PF07445.12 ORY39009.1 - 1.8 8.4 15.7 0.098 12.6 6.8 2.5 2 1 1 3 3 3 0 Primosomal replication protein priC RP-C_C PF11800.8 ORY39009.1 - 4.1 7.5 9.3 0.43 10.6 2.4 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region ETRAMP PF09716.10 ORY39009.1 - 5 7.3 9.9 44 4.2 9.9 2.9 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) ACBP PF00887.19 ORY39010.1 - 1.4e-20 73.3 0.0 2.1e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Ank PF00023.30 ORY39010.1 - 7.5e-15 54.6 0.0 3.7e-07 30.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 ORY39010.1 - 3.6e-13 49.9 0.0 5.6e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY39010.1 - 1.6e-11 44.5 0.1 2.3e-10 40.8 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY39010.1 - 2.6e-10 39.6 0.1 0.00062 20.0 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ORY39010.1 - 3.6e-10 39.9 0.0 1.6e-07 31.5 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Glyco_transf_7C PF02709.14 ORY39011.1 - 5e-19 67.8 0.0 8.6e-19 67.0 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_7N PF13733.6 ORY39011.1 - 1.1e-16 60.7 0.0 1.6e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 SURF1 PF02104.15 ORY39012.1 - 0.0071 16.6 0.0 0.0075 16.5 0.0 1.1 1 0 0 1 1 1 1 SURF1 family Cellulase PF00150.18 ORY39013.1 - 1.9e-17 63.6 0.4 2.4e-13 50.2 0.0 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 ORY39013.1 - 1.1e-16 61.2 0.0 2.4e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 ORY39014.1 - 7.2e-22 78.1 0.2 7.8e-15 55.0 0.0 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 ORY39014.1 - 5.3e-18 65.4 0.3 2.3e-17 63.3 0.1 2.1 2 0 0 2 2 2 1 Glycoside hydrolase family 5 C-terminal domain GTP1_OBG PF01018.22 ORY39015.1 - 1e-40 138.9 2.8 1.6e-40 138.3 2.8 1.3 1 0 0 1 1 1 1 GTP1/OBG MMR_HSR1 PF01926.23 ORY39015.1 - 3.8e-23 81.8 0.1 1e-22 80.3 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY39015.1 - 1.3e-09 37.8 0.0 2.9e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 ORY39015.1 - 2e-05 24.1 0.0 4.9e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family MeaB PF03308.16 ORY39015.1 - 0.038 13.0 0.1 2.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 ORY39015.1 - 0.084 12.3 0.4 0.33 10.4 0.0 2.0 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF3602 PF12223.8 ORY39015.1 - 0.9 10.2 3.7 7.3 7.3 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3602) ORC6 PF05460.13 ORY39015.1 - 1.1 8.5 5.6 1.5 8.1 5.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Baculo_F PF12259.8 ORY39017.1 - 0.0012 17.4 0.1 0.0014 17.2 0.1 1.0 1 0 0 1 1 1 1 Baculovirus F protein DUF4349 PF14257.6 ORY39017.1 - 0.14 11.6 1.4 0.17 11.3 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) CPSF100_C PF13299.6 ORY39018.1 - 0.06 13.5 0.7 0.11 12.6 0.7 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal OrfB_Zn_ribbon PF07282.11 ORY39018.1 - 1.8 8.6 4.1 0.62 10.0 0.9 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Acetyltransf_10 PF13673.7 ORY39019.1 - 7.8e-11 42.0 0.0 9.4e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY39019.1 - 2.8e-09 37.2 0.0 3.4e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY39019.1 - 4.2e-09 36.7 0.0 6.1e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY39019.1 - 3e-08 33.5 0.0 4.3e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 ORY39019.1 - 0.0031 17.6 0.1 0.0045 17.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 ORY39019.1 - 0.013 15.0 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase HTH_37 PF13744.6 ORY39019.1 - 0.053 13.5 0.0 0.092 12.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain UBX PF00789.20 ORY39020.1 - 1.5e-19 70.0 0.6 2.9e-11 43.4 0.1 2.5 2 0 0 2 2 2 2 UBX domain SHQ1 PF04925.15 ORY39021.1 - 9.9e-62 207.6 0.1 1.4e-61 207.1 0.1 1.2 1 0 0 1 1 1 1 SHQ1 protein Promethin PF16015.5 ORY39022.1 - 1.9e-09 37.4 12.1 2.4e-09 37.0 12.1 1.1 1 0 0 1 1 1 1 Promethin Xan_ur_permease PF00860.20 ORY39024.1 - 6.1e-70 235.9 31.8 1.3e-68 231.5 31.8 2.1 1 1 0 1 1 1 1 Permease family Cyclin_N PF00134.23 ORY39025.1 - 2.8e-11 43.3 0.6 2.1e-07 30.7 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 ORY39025.1 - 0.033 14.2 0.0 17 5.6 0.0 2.7 3 0 0 3 3 3 0 Transcription factor TFIIB repeat Inhibitor_I53 PF11714.8 ORY39025.1 - 0.27 11.5 1.0 0.66 10.2 1.0 1.7 1 0 0 1 1 1 0 Thrombin inhibitor Madanin MurJ PF03023.14 ORY39026.1 - 0.068 11.8 0.5 0.083 11.5 0.5 1.0 1 0 0 1 1 1 0 Lipid II flippase MurJ Trehalose_recp PF06151.13 ORY39026.1 - 0.16 10.6 1.0 0.32 9.6 0.6 1.6 1 1 1 2 2 2 0 Trehalose receptor Redoxin PF08534.10 ORY39027.1 - 8.2e-16 58.0 0.0 9.7e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ORY39027.1 - 2.5e-14 53.3 0.0 2.9e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF899 PF05988.12 ORY39027.1 - 0.0012 18.4 0.0 0.0015 18.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) Thioredoxin_8 PF13905.6 ORY39027.1 - 0.04 14.2 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.24 ORY39027.1 - 0.15 12.3 0.7 0.3 11.3 0.1 1.9 2 1 0 2 2 2 0 Glutaredoxin Citrate_synt PF00285.21 ORY39029.1 - 4.1e-93 312.3 0.0 6e-93 311.8 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain SCP2_2 PF13530.6 ORY39029.1 - 0.078 13.4 1.2 1.2 9.6 0.1 2.9 2 1 1 3 3 3 0 Sterol carrier protein domain 7tm_1 PF00001.21 ORY39030.1 - 2.7e-07 30.2 12.8 4e-07 29.6 12.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 ORY39030.1 - 0.065 13.0 17.3 0.17 11.6 17.3 1.7 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Bestrophin PF01062.21 ORY39031.1 - 3.9e-39 134.8 0.3 5.4e-39 134.3 0.3 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel zf-C2H2 PF00096.26 ORY39032.1 - 2.7e-11 43.3 21.1 0.0011 19.3 2.2 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY39032.1 - 4.3e-07 30.1 18.1 0.0027 18.0 1.9 4.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY39032.1 - 1.8e-06 28.3 22.6 0.01 16.6 2.1 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY39032.1 - 0.0024 18.1 4.4 1.8 8.9 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORY39032.1 - 0.0031 17.8 10.8 0.087 13.1 3.3 3.1 2 1 1 3 3 3 2 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 ORY39032.1 - 0.0067 16.4 1.7 0.0067 16.4 1.7 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORY39032.1 - 0.33 10.8 6.6 5.6 6.8 1.6 3.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-met PF12874.7 ORY39032.1 - 0.43 11.0 9.2 1.2 9.6 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type IBR PF01485.21 ORY39032.1 - 1.1 9.5 8.4 4.5 7.6 7.0 2.6 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain adh_short PF00106.25 ORY39034.1 - 4.8e-27 94.7 1.9 1.2e-26 93.4 1.9 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY39034.1 - 5e-14 52.4 0.8 1.1e-13 51.4 0.8 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Peptidase_S28 PF05577.12 ORY39034.1 - 5.9e-12 45.1 4.2 4.1e-09 35.8 0.1 2.8 1 1 1 2 2 2 2 Serine carboxypeptidase S28 Epimerase PF01370.21 ORY39034.1 - 0.02 14.4 0.3 0.041 13.4 0.3 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY39034.1 - 0.031 14.1 0.3 0.052 13.4 0.3 1.4 1 0 0 1 1 1 0 NAD(P)H-binding DNA_pol_lambd_f PF10391.9 ORY39034.1 - 0.052 13.4 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda PAXNEB PF05625.11 ORY39035.1 - 1.7e-55 188.7 0.0 2e-55 188.5 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein PAXNEB PF05625.11 ORY39037.1 - 7.5e-08 31.9 0.0 7.5e-08 31.9 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein Chitin_synth_2 PF03142.15 ORY39038.1 - 7.5e-18 64.4 0.1 2.7e-14 52.7 0.1 3.2 2 1 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORY39038.1 - 7e-14 52.3 0.0 1.2e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_hydro_16 PF00722.21 ORY39038.1 - 1.2e-13 50.9 0.1 2e-13 50.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.6 ORY39038.1 - 5.5e-10 39.5 12.4 5.5e-10 39.5 12.4 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORY39038.1 - 2.2e-07 30.5 0.0 4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORY39038.1 - 4.6e-06 26.6 0.0 0.00035 20.4 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 2 Pkinase PF00069.25 ORY39039.1 - 2e-60 204.4 0.0 3.5e-60 203.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY39039.1 - 1.8e-33 115.9 0.0 3.6e-33 114.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 ORY39039.1 - 1e-11 44.8 4.5 1e-06 28.7 3.3 3.9 3 1 0 3 3 2 2 Hr1 repeat C1_1 PF00130.22 ORY39039.1 - 1.5e-10 40.8 25.5 3.8e-06 26.7 6.9 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 ORY39039.1 - 4.2e-06 27.4 0.4 2.1e-05 25.1 0.4 2.3 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 ORY39039.1 - 0.0014 17.7 0.2 0.0028 16.6 0.2 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORY39039.1 - 0.0022 17.3 0.0 0.0022 17.3 0.0 2.0 2 0 0 2 2 1 1 Kinase-like BCA_ABC_TP_C PF12399.8 ORY39039.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter TFIIA PF03153.13 ORY39039.1 - 0.15 12.0 9.3 0.68 9.9 2.2 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TMEM247 PF15444.6 ORY39039.1 - 0.46 10.5 14.4 0.19 11.7 11.5 1.8 2 0 0 2 2 2 0 Transmembrane protein 247 RimM PF01782.18 ORY39039.1 - 0.92 9.8 2.6 2.1 8.6 0.1 2.7 2 1 1 3 3 3 0 RimM N-terminal domain DUF3874 PF12990.7 ORY39039.1 - 4.2 7.8 5.5 0.6 10.5 0.5 2.3 2 0 0 2 2 2 0 Domain of unknonw function from B. Theta Gene description (DUF3874) Pkinase_fungal PF17667.1 ORY39039.1 - 5.8 5.6 10.5 0.28 9.9 2.0 2.5 2 1 0 2 2 2 0 Fungal protein kinase Fer4_17 PF13534.6 ORY39039.1 - 8.5 7.0 14.4 17 6.1 12.5 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain CENP-F_leu_zip PF10473.9 ORY39041.1 - 0.21 11.6 24.4 0.25 11.4 4.3 2.7 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SHIPPO-rpt PF07004.12 ORY39042.1 - 0.00022 22.0 0.0 0.039 14.9 0.0 2.6 2 0 0 2 2 2 2 Sperm-tail PG-rich repeat Dpy-30 PF05186.13 ORY39044.1 - 0.00023 20.8 0.0 0.00042 19.9 0.0 1.5 1 0 0 1 1 1 1 Dpy-30 motif DUF2890 PF11081.8 ORY39044.1 - 0.046 13.8 0.3 0.069 13.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Pyridoxal_deC PF00282.19 ORY39045.1 - 5.2e-117 390.7 0.0 6.3e-117 390.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 ORY39045.1 - 0.0048 16.2 0.1 0.0077 15.6 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Ank_2 PF12796.7 ORY39046.1 - 1.1e-15 57.9 0.0 1.3e-06 28.9 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) SH3_1 PF00018.28 ORY39046.1 - 1.2e-08 34.4 0.0 2.4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Ank_5 PF13857.6 ORY39046.1 - 7.2e-08 32.6 4.7 0.2 12.0 0.2 5.1 3 2 2 5 5 5 2 Ankyrin repeats (many copies) SH3_2 PF07653.17 ORY39046.1 - 2.2e-06 27.2 0.0 5.3e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ORY39046.1 - 4e-06 26.6 0.1 8.5e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ank_4 PF13637.6 ORY39046.1 - 0.00012 22.6 9.5 1.4 9.6 0.0 6.5 3 3 5 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY39046.1 - 0.00018 21.7 2.6 18 6.3 0.2 6.0 6 0 0 6 6 6 0 Ankyrin repeat F-box-like PF12937.7 ORY39046.1 - 0.0025 17.7 0.3 0.0069 16.3 0.3 1.8 1 0 0 1 1 1 1 F-box-like Ank PF00023.30 ORY39046.1 - 0.048 14.1 5.4 36 5.0 0.1 5.1 3 2 1 4 4 4 0 Ankyrin repeat F-box PF00646.33 ORY39046.1 - 0.05 13.5 0.1 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 F-box domain Phi_1 PF04674.12 ORY39048.1 - 4.6e-25 88.5 0.8 7.2e-24 84.5 0.8 2.4 1 1 0 1 1 1 1 Phosphate-induced protein 1 conserved region SET PF00856.28 ORY39050.1 - 8.2e-13 49.1 0.0 9.9e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 SET domain Macoilin PF09726.9 ORY39052.1 - 0.41 9.1 5.1 0.43 9.1 5.1 1.0 1 0 0 1 1 1 0 Macoilin family CLASP_N PF12348.8 ORY39053.1 - 7.6e-25 87.8 2.8 5.2e-11 42.6 0.0 5.4 7 0 0 7 7 7 3 CLASP N terminal HEAT PF02985.22 ORY39053.1 - 4.5e-20 70.0 10.8 0.0088 16.2 0.0 10.4 10 0 0 10 10 9 5 HEAT repeat HEAT_2 PF13646.6 ORY39053.1 - 1.2e-15 57.7 6.8 0.018 15.4 0.0 8.2 7 1 1 8 8 8 4 HEAT repeats Cnd1 PF12717.7 ORY39053.1 - 5.9e-13 49.2 11.0 0.13 12.3 0.0 7.8 6 2 1 7 7 7 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 ORY39053.1 - 8e-12 45.6 1.6 0.31 11.7 0.0 7.7 8 1 1 9 9 9 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 ORY39053.1 - 2.9e-08 34.1 15.6 0.05 14.1 0.1 8.3 9 0 0 9 9 8 3 HEAT-like repeat RTP1_C1 PF10363.9 ORY39053.1 - 3.8e-06 27.0 0.9 1 9.6 0.0 5.6 6 0 0 6 6 6 2 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 ORY39053.1 - 0.00041 19.0 9.1 0.0031 16.1 0.8 4.8 5 1 0 5 5 5 1 Adaptin N terminal region Proteasom_PSMB PF10508.9 ORY39053.1 - 0.00058 18.5 3.9 0.023 13.2 0.3 3.5 4 0 0 4 4 4 1 Proteasome non-ATPase 26S subunit Arm PF00514.23 ORY39053.1 - 0.0034 17.4 7.1 21 5.4 0.0 5.7 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat MMS19_N PF14500.6 ORY39053.1 - 0.013 15.1 7.4 0.19 11.3 0.0 5.5 6 0 0 6 6 6 0 Dos2-interacting transcription regulator of RNA-Pol-II Cohesin_HEAT PF12765.7 ORY39053.1 - 0.027 14.8 1.8 4.1 7.8 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion V-ATPase_H_C PF11698.8 ORY39053.1 - 0.14 12.3 2.3 9.2 6.4 0.0 4.6 4 1 0 4 4 4 0 V-ATPase subunit H UreD PF01774.17 ORY39054.1 - 4.7e-49 167.2 0.0 5.8e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 UreD urease accessory protein DUF5378 PF17349.2 ORY39054.1 - 0.041 13.2 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) zf-C2H2 PF00096.26 ORY39055.1 - 1.9e-06 28.0 15.7 0.0042 17.5 6.8 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY39055.1 - 0.00057 20.5 13.3 0.13 13.2 5.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY39055.1 - 0.0013 19.1 1.6 0.0013 19.1 1.6 3.1 3 0 0 3 3 3 1 Zinc-finger double domain PSCyt3 PF07627.11 ORY39055.1 - 0.055 13.7 0.6 0.11 12.8 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1588) zf-met PF12874.7 ORY39055.1 - 0.071 13.5 8.5 0.085 13.3 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF1356 PF07092.12 ORY39056.1 - 2.4e-07 30.3 1.5 3.3e-07 29.8 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) LEA_2 PF03168.13 ORY39057.1 - 1.1e-08 35.5 0.0 1.8e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF1356 PF07092.12 ORY39057.1 - 0.00028 20.2 0.2 0.00041 19.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) PAP2_3 PF14378.6 ORY39057.1 - 0.065 12.9 0.1 0.08 12.6 0.1 1.1 1 0 0 1 1 1 0 PAP2 superfamily Thioredoxin PF00085.20 ORY39059.1 - 2.9e-05 24.0 0.0 4.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.20 ORY39060.1 - 0.00049 20.0 0.1 0.00095 19.1 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Pre-PUA PF17832.1 ORY39060.1 - 0.024 15.3 0.2 0.067 13.9 0.1 1.8 2 0 0 2 2 2 0 Pre-PUA-like domain iPGM_N PF06415.13 ORY39060.1 - 0.081 12.4 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 BPG-independent PGAM N-terminus (iPGM_N) Glyco_hydro_26 PF02156.15 ORY39061.1 - 0.00056 19.4 0.3 0.84 9.0 0.6 2.4 2 1 0 2 2 2 2 Glycosyl hydrolase family 26 EF-hand_5 PF13202.6 ORY39061.1 - 0.089 12.3 1.2 0.23 11.0 1.2 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 ORY39061.1 - 0.33 11.0 1.5 1 9.5 1.5 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 ORY39061.1 - 0.56 9.9 2.3 1.3 8.7 2.3 1.6 1 0 0 1 1 1 0 EF hand Gelsolin PF00626.22 ORY39062.1 - 7.7e-25 86.6 0.0 5.2e-09 35.9 0.0 6.4 6 0 0 6 6 6 6 Gelsolin repeat E1-E2_ATPase PF00122.20 ORY39063.1 - 3.1e-45 153.9 3.6 3.1e-45 153.9 3.6 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORY39063.1 - 1.2e-18 68.2 0.1 2.7e-18 67.0 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY39063.1 - 1.3e-13 50.4 0.1 1.7e-12 46.8 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.21 ORY39063.1 - 0.00026 20.7 10.1 0.00026 20.7 10.1 2.8 2 1 1 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORY39063.1 - 0.007 16.4 0.0 0.021 14.9 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY39063.1 - 0.024 14.4 0.2 0.061 13.1 0.1 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Gly_transf_sug PF04488.15 ORY39064.1 - 4.3e-21 75.4 1.1 1e-11 45.3 0.3 3.1 2 1 0 2 2 2 2 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 ORY39064.1 - 0.011 15.2 0.1 0.011 15.2 0.1 2.0 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 ORY39064.1 - 0.053 12.8 0.0 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DUF4131 PF13567.6 ORY39064.1 - 0.084 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Oxidored_molyb PF00174.19 ORY39065.1 - 1.5e-56 190.7 0.1 2.2e-56 190.2 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 ORY39065.1 - 1.6e-35 122.2 1.0 2.7e-35 121.4 1.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 ORY39065.1 - 4.6e-12 45.9 0.0 8.1e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Thiolase_N PF00108.23 ORY39066.1 - 2.1e-72 243.6 0.9 3.1e-72 243.0 0.9 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY39066.1 - 1.7e-46 156.9 0.9 3.1e-46 156.0 0.4 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ORY39066.1 - 0.026 14.1 1.0 0.099 12.2 0.8 2.1 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Cadherin_tail PF15974.5 ORY39066.1 - 0.13 12.6 0.5 0.53 10.6 0.3 2.0 1 1 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region DSPc PF00782.20 ORY39068.1 - 2.2e-30 105.2 0.0 2.9e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 ORY39068.1 - 0.0052 17.1 0.0 0.0076 16.5 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain V-SNARE_C PF12352.8 ORY39069.1 - 1.3e-12 47.8 3.3 1.3e-12 47.8 3.3 1.9 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 ORY39069.1 - 0.0033 17.3 0.3 0.013 15.4 0.0 2.1 2 1 0 2 2 2 1 Sec20 FOXP-CC PF16159.5 ORY39069.1 - 0.15 12.7 5.5 0.57 10.8 0.7 3.2 3 0 0 3 3 3 0 FOXP coiled-coil domain Dicty_CAR PF05462.11 ORY39070.1 - 0.0012 18.0 7.6 0.0039 16.4 2.7 2.2 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor APG6_N PF17675.1 ORY39071.1 - 1.9 9.0 8.7 5.3 7.6 0.1 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Romo1 PF10247.9 ORY39072.1 - 1.4e-07 31.8 15.9 0.00083 19.7 15.9 2.2 1 1 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 IDO PF01231.18 ORY39073.1 - 4.6e-124 414.5 0.0 5.5e-124 414.3 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 ORY39073.1 - 0.035 12.9 0.0 0.13 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) Lipase_3 PF01764.25 ORY39078.1 - 6.5e-05 22.8 0.0 9.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Macro PF01661.21 ORY39081.1 - 4.6e-21 75.0 0.6 8e-18 64.6 0.0 2.6 2 1 1 3 3 3 2 Macro domain Exo5 PF09810.9 ORY39082.1 - 3.9e-27 95.7 1.7 2.1e-24 86.7 1.7 2.9 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease NFACT-R_1 PF05670.13 ORY39083.1 - 1.2e-15 58.1 0.0 2.3e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 NFACT protein RNA binding domain DUF778 PF05608.12 ORY39083.1 - 0.0078 16.6 1.1 0.0099 16.3 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF778) DUF3363 PF11843.8 ORY39083.1 - 0.026 13.5 4.8 0.031 13.2 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) BST2 PF16716.5 ORY39083.1 - 0.077 13.6 5.4 0.12 13.0 4.3 1.8 1 1 0 1 1 1 0 Bone marrow stromal antigen 2 Fungal_trans PF04082.18 ORY39085.1 - 0.015 14.3 0.0 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF1979 PF09322.10 ORY39085.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1979) Metallophos PF00149.28 ORY39086.1 - 8.5e-39 134.2 0.2 1.3e-38 133.6 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORY39086.1 - 0.0027 18.1 0.5 0.0055 17.1 0.5 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 ORY39086.1 - 0.18 11.4 0.0 0.26 10.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain MOZART1 PF12554.8 ORY39087.1 - 5.8e-22 77.2 0.2 6.7e-22 77.0 0.2 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated PMEI PF04043.15 ORY39087.1 - 0.066 13.6 0.4 0.074 13.4 0.4 1.0 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor FATC PF02260.20 ORY39087.1 - 0.085 12.7 0.1 13 5.7 0.0 2.2 1 1 1 2 2 2 0 FATC domain PRELI PF04707.14 ORY39088.1 - 5.3e-35 120.5 5.6 3.1e-27 95.3 1.4 2.2 2 0 0 2 2 2 2 PRELI-like family Fungal_trans PF04082.18 ORY39089.1 - 2.9e-05 23.3 0.0 4.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FGGY_C PF02782.16 ORY39090.1 - 5.2e-15 55.7 0.0 1e-14 54.7 0.0 1.5 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 ORY39090.1 - 2.8e-14 53.3 0.0 6.7e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain LRR_8 PF13855.6 ORY39091.1 - 4.7e-32 109.5 36.5 1.8e-11 43.6 4.2 5.5 2 2 1 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 ORY39091.1 - 1.9e-27 94.8 35.8 2.5e-06 27.7 6.4 5.7 4 2 0 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY39091.1 - 8.1e-12 44.0 33.6 1.8 9.4 0.0 10.0 9 1 0 9 9 9 6 Leucine Rich Repeat LRR_6 PF13516.6 ORY39091.1 - 3.1e-08 33.0 39.7 0.029 14.4 0.0 9.0 9 0 0 9 9 9 4 Leucine Rich repeat F-box-like PF12937.7 ORY39091.1 - 0.00016 21.5 0.0 0.00039 20.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY39091.1 - 0.00036 20.3 0.1 0.0011 18.8 0.1 1.7 1 0 0 1 1 1 1 F-box domain LRR_9 PF14580.6 ORY39091.1 - 0.0011 18.5 4.1 0.0011 18.5 4.1 2.7 1 1 2 3 3 3 2 Leucine-rich repeat LRR_5 PF13306.6 ORY39091.1 - 0.86 9.6 4.2 0.53 10.2 1.2 2.1 2 1 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) NOA36 PF06524.12 ORY39091.1 - 1.8 7.8 7.9 3.2 7.0 7.9 1.4 1 0 0 1 1 1 0 NOA36 protein VIT1 PF01988.19 ORY39092.1 - 7.4e-71 238.4 0.6 1.1e-70 237.9 0.6 1.2 1 0 0 1 1 1 1 VIT family DUF5326 PF17260.2 ORY39092.1 - 1.2 9.3 4.6 9.2 6.5 0.6 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5326) Laminin_G_1 PF00054.23 ORY39093.1 - 0.098 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Laminin G domain Retrotran_gag_2 PF14223.6 ORY39094.1 - 2.9e-05 23.8 0.1 3.7e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type WAK PF08488.11 ORY39094.1 - 0.093 13.3 0.0 0.13 12.8 0.0 1.2 1 0 0 1 1 1 0 Wall-associated kinase Peptidase_S8 PF00082.22 ORY39097.1 - 1.1e-37 129.9 3.6 1.5e-37 129.5 3.6 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 ORY39097.1 - 4e-22 78.1 0.0 9.5e-22 76.8 0.0 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain Peptidase_S8_N PF16361.5 ORY39097.1 - 0.059 13.8 0.0 0.11 13.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal of Subtilase family PPP1R35_C PF15503.6 ORY39099.1 - 0.00045 20.0 3.3 0.00097 19.0 3.3 1.6 1 0 0 1 1 1 1 Protein phosphatase 1 regulatory subunit 35 C-terminus SNARE_assoc PF09335.11 ORY39100.1 - 4.6e-08 33.6 0.5 4.6e-08 33.6 0.5 2.9 4 1 0 4 4 4 1 SNARE associated Golgi protein Vut_1 PF02592.15 ORY39100.1 - 0.09 13.1 12.7 0.095 13.0 4.8 3.4 2 1 0 2 2 2 0 Putative vitamin uptake transporter SNARE_assoc PF09335.11 ORY39101.1 - 1.5e-08 35.1 1.7 1.5e-08 35.1 1.7 3.5 4 0 0 4 4 4 1 SNARE associated Golgi protein Phage_holin_2_1 PF04971.12 ORY39101.1 - 0.053 13.5 0.5 0.053 13.5 0.5 3.1 3 0 0 3 3 3 0 Bacteriophage P21 holin S Vut_1 PF02592.15 ORY39101.1 - 0.074 13.4 0.0 0.074 13.4 0.0 3.0 3 2 0 3 3 3 0 Putative vitamin uptake transporter Ank_2 PF12796.7 ORY39102.1 - 2.2e-08 34.6 0.0 0.12 13.0 0.0 4.1 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY39102.1 - 2.4e-07 30.5 0.5 0.54 11.0 0.1 4.9 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 ORY39102.1 - 3.9e-07 30.2 0.4 0.016 15.6 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 ORY39102.1 - 0.00057 20.4 0.0 3.8 8.2 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY39102.1 - 0.058 13.7 0.0 9.9 6.6 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeats (many copies) zf-RING_2 PF13639.6 ORY39103.1 - 2e-13 50.4 7.5 2.9e-13 49.9 7.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY39103.1 - 3.5e-09 36.3 8.1 6.3e-09 35.5 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY39103.1 - 8.9e-09 34.9 2.6 1.6e-08 34.1 2.6 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 ORY39103.1 - 5.6e-08 32.9 10.4 2.2e-07 31.0 10.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORY39103.1 - 7.2e-08 32.2 7.4 1.1e-07 31.5 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY39103.1 - 9.5e-08 31.9 4.5 1.5e-07 31.3 4.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY39103.1 - 3.4e-07 30.2 4.8 6.7e-07 29.2 4.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 ORY39103.1 - 9e-06 25.5 4.4 1.8e-05 24.5 4.4 1.5 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 ORY39103.1 - 4e-05 23.4 3.1 6.6e-05 22.7 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORY39103.1 - 0.0031 17.5 5.5 0.008 16.2 5.5 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 ORY39103.1 - 0.0095 16.1 5.1 0.084 13.1 5.1 2.2 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 ORY39103.1 - 0.011 15.9 3.0 0.023 14.8 3.0 1.6 1 1 0 1 1 1 0 RING-variant domain Baculo_RING PF05883.11 ORY39103.1 - 0.038 14.0 0.2 0.073 13.1 0.2 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Zn_ribbon_17 PF17120.5 ORY39103.1 - 0.073 12.7 5.2 0.15 11.7 5.2 1.5 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 ORY39103.1 - 0.14 12.4 2.1 0.21 11.8 2.1 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3H2C3 PF17122.5 ORY39103.1 - 0.14 12.2 5.8 0.26 11.4 5.8 1.5 1 0 0 1 1 1 0 Zinc-finger Suf PF05843.14 ORY39103.1 - 0.18 11.8 2.4 0.3 11.0 2.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-Nse PF11789.8 ORY39103.1 - 0.24 11.2 4.5 0.5 10.2 4.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_1 PF14446.6 ORY39103.1 - 0.26 11.3 4.0 2.5 8.1 1.9 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.6 ORY39103.1 - 0.29 11.3 4.5 1.1 9.5 4.5 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 ORY39103.1 - 0.35 10.7 5.8 0.58 10.0 5.8 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 ORY39103.1 - 1.6 8.7 5.2 3.8 7.5 5.2 1.7 1 1 0 1 1 1 0 PHD-finger BLM10_mid PF16507.5 ORY39104.1 - 9.1e-128 427.2 0.1 4.8e-126 421.5 0.0 2.8 2 1 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 ORY39104.1 - 2.7e-32 110.5 0.2 2.1e-31 107.6 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) RFC1 PF08519.12 ORY39104.1 - 0.16 12.1 0.1 0.53 10.4 0.1 1.9 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain MMR_HSR1 PF01926.23 ORY39105.1 - 1e-08 35.2 0.1 1.7e-07 31.3 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY39105.1 - 1.2e-05 24.8 0.7 0.012 15.1 0.1 3.2 4 0 0 4 4 4 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 ORY39105.1 - 3.3e-05 23.5 0.2 0.00081 19.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 ORY39105.1 - 0.038 13.7 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY39105.1 - 0.042 13.7 0.5 2.1 8.2 0.3 2.8 2 1 0 2 2 2 0 RsgA GTPase ATP_bind_1 PF03029.17 ORY39105.1 - 0.052 13.3 0.0 0.18 11.6 0.0 2.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein YscJ_FliF_C PF08345.11 ORY39108.1 - 0.025 14.9 0.1 0.03 14.7 0.1 1.1 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal SIR2 PF02146.17 ORY39109.1 - 4e-51 173.5 0.0 4.8e-50 169.9 0.0 2.3 1 1 0 1 1 1 1 Sir2 family zf-UBP PF02148.19 ORY39109.1 - 4.8e-15 55.6 6.5 1e-14 54.6 6.5 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 ORY39109.1 - 0.02 14.6 0.1 0.052 13.3 0.1 1.7 1 0 0 1 1 1 0 Variant UBP zinc finger ABC_transp_aux PF09822.9 ORY39109.1 - 0.15 11.5 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 ABC-type uncharacterized transport system zinc_ribbon_9 PF14369.6 ORY39109.1 - 7.5 6.9 10.7 5.6 7.3 0.2 3.4 3 1 1 4 4 4 0 zinc-ribbon SIR2 PF02146.17 ORY39110.1 - 6.3e-52 176.1 0.0 6.7e-50 169.4 0.0 2.4 1 1 0 1 1 1 1 Sir2 family zf-UBP PF02148.19 ORY39110.1 - 4.3e-17 62.2 6.5 8.4e-17 61.3 6.5 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Zn-ribbon_8 PF09723.10 ORY39110.1 - 0.16 12.1 0.8 1.4 9.1 0.1 2.9 3 0 0 3 3 3 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 ORY39110.1 - 0.79 10.0 4.1 3.4 8.0 0.1 2.9 3 0 0 3 3 3 0 zinc-ribbon An_peroxidase PF03098.15 ORY39111.1 - 1.4e-13 50.3 0.3 1.4e-05 23.9 0.0 3.1 1 1 2 3 3 3 3 Animal haem peroxidase DUF321 PF03778.13 ORY39111.1 - 0.074 12.7 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF321) An_peroxidase PF03098.15 ORY39112.1 - 2e-08 33.3 0.0 2.3e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Animal haem peroxidase RabGAP-TBC PF00566.18 ORY39113.1 - 3.3e-54 183.8 1.8 5e-54 183.2 1.8 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain IL34 PF15036.6 ORY39113.1 - 0.0081 16.2 0.1 0.028 14.5 0.0 1.9 1 1 1 2 2 2 1 Interleukin 34 Fungal_trans PF04082.18 ORY39114.1 - 0.00026 20.1 1.3 0.00086 18.4 0.1 2.4 3 0 0 3 3 3 1 Fungal specific transcription factor domain Pkinase PF00069.25 ORY39115.1 - 1.7e-05 24.3 0.1 5.5e-05 22.7 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Dynein_light PF01221.18 ORY39116.1 - 2e-43 146.6 1.8 2.2e-43 146.4 1.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 FA_desaturase PF00487.24 ORY39119.1 - 0.043 13.7 2.0 0.11 12.3 2.0 1.6 1 0 0 1 1 1 0 Fatty acid desaturase DUF4514 PF14986.6 ORY39119.1 - 1.6 8.7 4.6 13 5.9 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4514) Dicty_CAR PF05462.11 ORY39121.1 - 3.7e-05 23.0 17.7 0.0013 17.9 15.9 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor Git3 PF11710.8 ORY39121.1 - 0.0057 16.5 15.2 0.0084 15.9 15.2 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_2 PF00002.24 ORY39121.1 - 0.062 12.6 15.8 0.1 11.9 15.8 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) DUF4834 PF16118.5 ORY39121.1 - 0.19 12.7 1.9 6.1 7.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) LRR_8 PF13855.6 ORY39122.1 - 5.2e-15 55.0 12.9 8.5e-07 28.6 2.5 3.6 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY39122.1 - 1.7e-10 41.0 17.5 0.00063 20.1 3.1 4.4 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY39122.1 - 3.6e-07 29.8 4.8 1.5 9.6 0.1 5.3 5 0 0 5 5 5 2 Leucine Rich Repeat TRCF PF03461.15 ORY39122.1 - 0.15 12.5 0.0 3 8.3 0.0 2.6 2 1 1 3 3 3 0 TRCF domain LRR_6 PF13516.6 ORY39122.1 - 0.24 11.5 16.8 25 5.3 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich repeat UCH PF00443.29 ORY39123.1 - 6.9e-14 51.9 0.0 4.8e-13 49.2 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY39123.1 - 4.2e-06 26.6 0.3 5e-05 23.0 0.3 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase 7tm_3 PF00003.22 ORY39125.1 - 3.4e-26 92.4 16.8 4.2e-26 92.1 16.8 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 ORY39126.1 - 1.1e-20 74.0 0.0 1.5e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY39126.1 - 0.00089 19.0 0.1 0.0021 17.8 0.1 1.6 2 0 0 2 2 2 1 Periplasmic binding protein RNA_polI_A34 PF08208.11 ORY39128.1 - 1.1e-06 28.9 0.8 1.1e-06 28.9 0.8 2.9 2 1 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 AIM3 PF17096.5 ORY39128.1 - 7.2 7.6 11.3 19 6.3 1.3 2.4 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 RRM_1 PF00076.22 ORY39129.1 - 4.4e-46 154.6 0.0 1.6e-15 56.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY39129.1 - 0.0001 21.9 0.0 0.092 12.4 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY39129.1 - 0.00088 19.3 0.0 0.06 13.5 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 ORY39129.1 - 0.015 15.3 0.0 0.28 11.2 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif TFIIA PF03153.13 ORY39129.1 - 0.026 14.5 4.2 0.041 13.9 4.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 ORY39129.1 - 0.043 12.8 2.9 0.049 12.6 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) RRM_occluded PF16842.5 ORY39129.1 - 0.12 12.2 0.0 3.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_3 PF08777.11 ORY39129.1 - 0.2 11.7 3.5 0.23 11.5 0.0 2.5 3 0 0 3 3 3 0 RNA binding motif Activator_LAG-3 PF11498.8 ORY39129.1 - 0.37 9.7 20.5 5.8 5.8 21.5 2.0 2 0 0 2 2 2 0 Transcriptional activator LAG-3 UPF0560 PF10577.9 ORY39129.1 - 1.5 7.2 3.2 2.1 6.7 3.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF5349 PF17298.2 ORY39129.1 - 2.2 8.0 8.6 6.4 6.4 8.5 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5349) Fungal_trans PF04082.18 ORY39130.1 - 4.3e-07 29.2 0.1 6.8e-07 28.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 ORY39132.1 - 0.0081 15.2 0.3 0.01 14.9 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Il2rg PF15874.5 ORY39132.1 - 0.02 15.1 0.0 0.043 14.1 0.0 1.5 1 0 0 1 1 1 0 Putative Interleukin 2 receptor, gamma chain Fungal_trans PF04082.18 ORY39133.1 - 8.7e-05 21.7 0.2 0.00011 21.4 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF5422 PF17459.2 ORY39134.1 - 0.011 16.0 0.6 0.012 15.8 0.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5422) DUF2244 PF10003.9 ORY39134.1 - 0.15 11.7 0.9 0.2 11.3 0.9 1.1 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Fungal_trans PF04082.18 ORY39135.1 - 0.0025 16.9 1.2 0.0051 15.9 1.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_kinase PF00696.28 ORY39137.1 - 5.3e-07 29.5 0.0 2.2e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Amino acid kinase family dbPDZ_assoc PF16610.5 ORY39138.1 - 0.35 11.1 6.9 0.1 12.8 2.2 2.2 2 1 0 2 2 2 0 Unstructured region between two PDZ domains on Dlg5 Fungal_trans PF04082.18 ORY39140.1 - 1.1e-06 27.8 0.9 1.6e-06 27.4 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Gtr1_RagA PF04670.12 ORY39141.1 - 2.3e-22 79.5 0.1 3e-22 79.1 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNase_H2-Ydr279 PF09468.10 ORY39141.1 - 0.049 13.8 0.0 0.054 13.7 0.0 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain GHMP_kinases_N PF00288.26 ORY39142.1 - 3.9e-10 39.8 0.5 9.1e-10 38.6 0.5 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ORY39142.1 - 6.3e-06 26.5 0.3 6.3e-06 26.5 0.3 2.5 2 1 1 3 3 3 1 GHMP kinases C terminal Peripla_BP_2 PF01497.18 ORY39144.1 - 1.1e-07 31.7 0.0 1.5e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Peripla_BP_2 PF01497.18 ORY39145.1 - 0.032 13.8 0.0 0.28 10.7 0.0 2.1 1 1 1 2 2 2 0 Periplasmic binding protein DUF913 PF06025.12 ORY39145.1 - 0.077 12.0 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Fungal_trans PF04082.18 ORY39147.1 - 2.8e-06 26.6 0.6 3.9e-06 26.1 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain CENP-F_leu_zip PF10473.9 ORY39148.1 - 0.00022 21.3 2.9 0.00031 20.8 2.9 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.10 ORY39148.1 - 0.0052 17.0 0.6 0.0057 16.9 0.6 1.2 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.12 ORY39148.1 - 0.013 15.5 4.6 0.026 14.6 4.6 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Cep57_CLD_2 PF14197.6 ORY39148.1 - 0.015 15.3 3.3 0.12 12.5 3.3 2.1 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF745 PF05335.13 ORY39148.1 - 0.019 14.7 0.5 0.025 14.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) ATG16 PF08614.11 ORY39148.1 - 0.02 15.1 4.0 0.028 14.6 4.0 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) V-ATPase_G_2 PF16999.5 ORY39148.1 - 0.029 14.8 2.8 0.045 14.2 2.8 1.2 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF5320 PF17253.2 ORY39148.1 - 0.035 15.2 0.6 0.06 14.4 0.2 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5320) DUF2508 PF10704.9 ORY39148.1 - 0.04 14.1 0.2 0.068 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) LZ_Tnp_IS66 PF13007.7 ORY39148.1 - 0.041 14.7 0.6 0.065 14.0 0.6 1.4 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain bZIP_1 PF00170.21 ORY39148.1 - 0.15 12.2 1.4 12 6.1 0.3 2.3 2 0 0 2 2 2 0 bZIP transcription factor Csm1_N PF18504.1 ORY39148.1 - 2.7 8.4 7.9 0.26 11.6 1.2 2.4 2 1 1 3 3 3 0 Csm1 N-terminal domain Mucin15 PF15672.5 ORY39149.1 - 0.12 11.9 5.7 0.13 11.7 5.7 1.1 1 0 0 1 1 1 0 Cell-membrane associated Mucin15 MetOD2 PF18548.1 ORY39149.1 - 0.17 12.0 2.5 7.9 6.7 0.4 2.7 1 1 2 3 3 3 0 Metanogen output domain 2 FlgT_C PF16538.5 ORY39149.1 - 0.21 12.2 1.8 0.26 11.8 0.6 1.9 2 0 0 2 2 2 0 Flagellar assembly protein T, C-terminal domain DHR10 PF18595.1 ORY39149.1 - 0.53 10.3 9.3 0.26 11.4 6.9 1.5 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Troponin PF00992.20 ORY39150.1 - 0.0034 17.7 2.2 0.004 17.5 2.2 1.1 1 0 0 1 1 1 1 Troponin NepR PF18557.1 ORY39150.1 - 0.011 15.4 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Anti-sigma factor NepR TSC22 PF01166.18 ORY39150.1 - 0.026 14.8 3.2 0.071 13.4 2.7 1.9 1 1 1 2 2 2 0 TSC-22/dip/bun family Csm1_N PF18504.1 ORY39150.1 - 0.04 14.3 6.5 0.095 13.0 5.9 1.8 1 1 1 2 2 2 0 Csm1 N-terminal domain CENP-H PF05837.12 ORY39150.1 - 0.051 14.0 3.3 0.07 13.5 3.3 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) SlyX PF04102.12 ORY39150.1 - 0.077 13.6 1.5 0.13 12.9 1.5 1.4 1 0 0 1 1 1 0 SlyX YabA PF06156.13 ORY39150.1 - 0.084 13.5 0.5 0.12 13.0 0.5 1.2 1 0 0 1 1 1 0 Initiation control protein YabA CAP59_mtransfer PF11735.8 ORY39150.1 - 0.091 12.4 0.2 0.11 12.2 0.2 1.1 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 DUF4404 PF14357.6 ORY39150.1 - 0.25 12.0 2.6 0.38 11.4 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) BTB PF00651.31 ORY39151.1 - 3.5e-05 24.0 0.0 0.00017 21.8 0.0 2.1 1 1 0 1 1 1 1 BTB/POZ domain Zn_clus PF00172.18 ORY39152.1 - 0.0014 18.7 14.9 0.0014 18.7 14.9 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY39154.1 - 0.015 14.4 0.6 0.024 13.7 0.6 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain SNF2_N PF00176.23 ORY39156.1 - 5.5e-70 235.8 0.1 1.4e-69 234.5 0.1 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY39156.1 - 4.2e-20 72.2 0.8 1.1e-17 64.3 0.0 3.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain SnAC PF14619.6 ORY39156.1 - 6.2e-12 46.0 1.0 3.3e-11 43.6 0.3 2.7 1 1 1 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex Bromodomain PF00439.25 ORY39156.1 - 7.6e-12 45.1 0.0 2.3e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Bromodomain ResIII PF04851.15 ORY39156.1 - 1.5e-09 38.1 2.2 3e-09 37.1 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HSA PF07529.13 ORY39156.1 - 2.1e-08 34.4 6.4 2.8e-08 34.0 2.0 2.7 2 0 0 2 2 2 1 HSA QLQ PF08880.11 ORY39156.1 - 1.1e-06 28.3 2.5 2.7e-06 27.0 2.5 1.8 1 0 0 1 1 1 1 QLQ DEAD PF00270.29 ORY39156.1 - 0.00012 21.9 0.9 0.00046 20.0 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 ORY39156.1 - 0.00026 20.7 1.3 0.00054 19.7 0.1 2.2 2 1 0 2 2 2 1 SWI2/SNF2 ATPase DUF2982 PF11201.8 ORY39156.1 - 0.014 14.9 0.2 0.032 13.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2982) HDA2-3 PF11496.8 ORY39156.1 - 0.021 14.0 0.1 0.18 11.0 0.1 2.3 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 AAA_14 PF13173.6 ORY39156.1 - 0.023 14.7 0.3 0.19 11.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF4336 PF14234.6 ORY39156.1 - 0.18 11.0 0.0 3.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4336) DUF2664 PF10867.8 ORY39156.1 - 2.7 8.5 9.3 24 5.5 0.2 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2664) 7tm_3 PF00003.22 ORY39157.1 - 4.7e-13 49.4 13.1 8.7e-13 48.5 13.1 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 ORY39158.1 - 0.014 14.5 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Receptor family ligand binding region 7tm_2 PF00002.24 ORY39159.1 - 0.018 14.3 6.9 0.032 13.5 6.9 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) GPR_Gpa2_C PF11970.8 ORY39159.1 - 0.043 13.9 0.1 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term FtsH_ext PF06480.15 ORY39159.1 - 0.24 11.8 3.3 0.43 11.0 3.3 1.4 1 0 0 1 1 1 0 FtsH Extracellular CASP_C PF08172.12 ORY39161.1 - 1.2e-42 146.1 4.3 1.2e-42 146.1 4.3 4.8 3 2 1 4 4 4 1 CASP C terminal DASH_Hsk3 PF08227.11 ORY39161.1 - 0.027 14.8 1.7 0.027 14.8 1.7 3.1 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like ZapB PF06005.12 ORY39161.1 - 0.27 11.7 0.1 0.27 11.7 0.1 6.4 5 1 0 5 5 5 0 Cell division protein ZapB Tweety PF04906.13 ORY39161.1 - 0.69 8.5 2.8 0.92 8.1 1.7 1.8 1 1 0 1 1 1 0 Tweety PgaD PF13994.6 ORY39164.1 - 0.00052 20.1 1.0 0.0013 18.8 1.0 1.6 1 0 0 1 1 1 1 PgaD-like protein Frizzled PF01534.17 ORY39164.1 - 0.0091 15.1 1.5 0.013 14.6 1.5 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.24 ORY39164.1 - 0.014 14.7 0.6 0.023 14.0 0.6 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) HofP PF10748.9 ORY39164.1 - 0.041 13.4 0.1 0.079 12.5 0.1 1.4 1 0 0 1 1 1 0 DNA utilization proteins HofP IPK PF03770.16 ORY39165.1 - 3.3e-44 151.1 0.0 1.1e-43 149.4 0.0 1.7 1 1 0 1 1 1 1 Inositol polyphosphate kinase DUF5364 PF17322.2 ORY39167.1 - 0.009 16.3 0.8 0.29 11.5 1.1 2.0 1 1 1 2 2 2 1 Family of unknown function (DUF5364) DUF2840 PF11000.8 ORY39167.1 - 0.099 12.4 0.0 0.22 11.3 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2840) DUF4231 PF14015.6 ORY39169.1 - 0.016 15.7 0.0 0.028 14.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Tetraspanin PF00335.20 ORY39169.1 - 0.024 14.3 0.9 0.048 13.4 0.2 1.6 2 0 0 2 2 2 0 Tetraspanin family ALP_N PF17989.1 ORY39171.1 - 0.029 14.5 0.0 0.041 14.1 0.0 1.3 1 0 0 1 1 1 0 Actin like proteins N terminal domain ESR1_C PF12743.7 ORY39171.1 - 4.7 7.1 7.1 10 6.0 0.5 2.5 2 0 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal DUF4541 PF15074.6 ORY39172.1 - 0.15 12.7 0.2 0.26 11.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4541) zf-C2H2 PF00096.26 ORY39174.1 - 7e-13 48.3 21.9 6.6e-06 26.3 5.0 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY39174.1 - 3e-09 36.9 20.2 6.2e-05 23.5 4.4 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY39174.1 - 3.2e-09 36.8 17.1 2.3e-05 24.6 4.4 2.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY39174.1 - 2.6e-07 30.5 16.9 0.0072 16.3 0.7 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY39174.1 - 1.3e-06 28.5 6.2 0.00064 19.9 1.3 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 ORY39174.1 - 0.00036 20.8 4.8 0.00054 20.2 4.8 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 ORY39174.1 - 0.00085 19.0 8.3 0.011 15.5 6.0 3.0 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-met PF12874.7 ORY39174.1 - 0.0015 18.8 8.3 0.5 10.8 0.6 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 ORY39174.1 - 0.0018 18.6 7.6 0.12 12.8 2.0 2.3 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 ORY39174.1 - 0.013 15.2 8.5 0.16 11.7 1.8 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HE PF16278.5 ORY39174.1 - 0.013 15.9 8.2 0.2 12.1 0.5 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger DUF2256 PF10013.9 ORY39174.1 - 0.044 13.9 2.3 3.6 7.8 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf_C2H2_ZHX PF18387.1 ORY39174.1 - 0.048 13.3 9.2 0.17 11.6 0.3 2.7 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain GAGA PF09237.11 ORY39174.1 - 0.072 12.9 7.1 1.2 9.0 2.1 2.1 1 1 1 2 2 2 0 GAGA factor zf-CHCC PF10276.9 ORY39174.1 - 0.12 12.4 3.7 5.5 7.1 1.8 2.5 2 1 0 2 2 2 0 Zinc-finger domain zf_ZIC PF18366.1 ORY39174.1 - 0.14 12.3 4.3 2 8.6 1.4 2.9 1 1 2 3 3 3 0 Zic proteins zinc finger domain DUF4187 PF13821.6 ORY39174.1 - 0.15 11.9 4.7 0.42 10.4 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4187) FYVE PF01363.21 ORY39174.1 - 0.32 11.2 11.1 0.21 11.8 1.8 2.5 1 1 1 2 2 2 0 FYVE zinc finger zinc_ribbon_9 PF14369.6 ORY39174.1 - 3.5 8.0 8.9 1.2 9.4 0.3 2.6 2 1 0 2 2 2 0 zinc-ribbon zf-BED PF02892.15 ORY39174.1 - 4.8 7.3 12.6 1.3 9.1 7.3 2.6 1 1 2 3 3 3 0 BED zinc finger CPL PF08144.11 ORY39176.1 - 0.077 13.3 0.2 0.12 12.8 0.2 1.3 1 0 0 1 1 1 0 CPL (NUC119) domain DUF2184 PF09950.9 ORY39176.1 - 0.15 11.4 0.9 1.6 8.1 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2184) Zn_clus PF00172.18 ORY39179.1 - 0.00024 21.1 8.5 0.00056 20.0 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_G7 PF05503.12 ORY39179.1 - 0.0082 15.1 0.1 0.013 14.5 0.1 1.2 1 0 0 1 1 1 1 Poxvirus G7-like LRR_6 PF13516.6 ORY39181.1 - 0.022 14.8 0.1 0.047 13.8 0.1 1.6 1 0 0 1 1 1 0 Leucine Rich repeat PM0188 PF11477.8 ORY39181.1 - 0.049 12.8 1.2 3.7 6.6 0.1 2.2 2 0 0 2 2 2 0 Sialyltransferase PMO188 Neuromodulin PF06614.11 ORY39186.1 - 0.0046 17.2 4.9 0.0058 16.8 4.9 1.1 1 0 0 1 1 1 1 Neuromodulin AAA PF00004.29 ORY39187.1 - 8.5e-39 133.0 0.0 1.6e-38 132.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY39187.1 - 7.2e-14 51.3 1.1 1.2e-13 50.6 0.1 1.9 2 0 0 2 2 1 1 AAA+ lid domain Vps4_C PF09336.10 ORY39187.1 - 3.8e-06 26.8 0.4 1.5e-05 24.9 0.0 2.3 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 ORY39187.1 - 4.1e-06 26.6 0.0 7.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ORY39187.1 - 1.3e-05 25.4 0.0 2.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 ORY39187.1 - 1.5e-05 24.4 0.1 2.8e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 ORY39187.1 - 0.00011 22.4 0.0 0.00031 20.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ORY39187.1 - 0.00015 21.7 0.0 0.00066 19.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY39187.1 - 0.00016 22.0 0.4 0.0029 17.9 0.4 2.4 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ORY39187.1 - 0.00027 20.4 0.0 0.00067 19.1 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 ORY39187.1 - 0.00081 19.4 0.0 0.0021 18.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 ORY39187.1 - 0.001 18.8 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 ORY39187.1 - 0.0031 17.9 0.0 0.0083 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 ORY39187.1 - 0.0032 18.0 0.4 0.0084 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 ORY39187.1 - 0.0058 16.0 0.2 0.63 9.3 0.1 2.4 1 1 1 2 2 2 1 KaiC AAA_7 PF12775.7 ORY39187.1 - 0.0067 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 ORY39187.1 - 0.0081 16.5 0.0 0.019 15.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.27 ORY39187.1 - 0.0098 16.4 0.0 0.018 15.6 0.0 1.5 1 1 0 1 1 1 1 ABC transporter Cytidylate_kin PF02224.18 ORY39187.1 - 0.014 15.2 0.9 0.6 9.8 0.0 2.7 2 1 0 3 3 3 0 Cytidylate kinase AAA_24 PF13479.6 ORY39187.1 - 0.017 14.9 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ORY39187.1 - 0.031 14.5 0.1 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 ORY39187.1 - 0.036 13.8 0.0 0.45 10.2 0.0 2.3 1 1 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 ORY39187.1 - 0.045 13.7 0.1 0.13 12.2 0.0 1.8 2 1 0 2 2 1 0 NACHT domain T2SSE PF00437.20 ORY39187.1 - 0.056 12.5 0.0 0.13 11.3 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Parvo_NS1 PF01057.17 ORY39187.1 - 0.059 12.5 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 ORY39187.1 - 0.075 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 ORY39187.1 - 0.1 12.1 0.0 0.35 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 ORY39187.1 - 0.12 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sel1 PF08238.12 ORY39190.1 - 4.3e-34 116.2 10.8 1.8e-07 31.6 0.3 8.6 10 0 0 10 10 9 5 Sel1 repeat TPR_7 PF13176.6 ORY39190.1 - 5.7e-11 41.6 1.2 0.012 15.6 0.0 5.8 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY39190.1 - 1.8e-07 31.7 9.6 0.0025 18.4 0.2 5.7 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY39190.1 - 2.4e-06 27.3 2.4 0.19 12.0 0.0 5.1 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY39190.1 - 3.5e-06 26.6 7.8 1.2 9.1 0.0 6.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY39190.1 - 5.2e-05 23.7 4.6 9.4 6.8 0.0 5.3 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY39190.1 - 7.9e-05 22.5 17.7 0.81 10.0 0.0 7.9 7 2 1 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY39190.1 - 0.00016 21.8 0.3 16 6.1 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY39190.1 - 0.00018 21.9 7.5 1.2 10.0 0.0 6.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY39190.1 - 0.018 15.3 6.3 0.11 12.9 0.1 4.4 3 1 0 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY39190.1 - 0.078 12.7 6.3 0.79 9.5 0.1 4.5 4 0 0 4 4 4 0 TPR repeat HemY_N PF07219.13 ORY39190.1 - 0.27 11.4 3.0 10 6.4 0.1 3.1 3 0 0 3 3 3 0 HemY protein N-terminus NSF PF02071.20 ORY39190.1 - 5.7 8.2 5.3 1.6e+02 3.9 0.1 4.8 5 0 0 5 5 4 0 Aromatic-di-Alanine (AdAR) repeat Pantoate_transf PF02548.15 ORY39197.1 - 1.7e-36 125.9 8.0 1.7e-29 103.0 2.9 4.0 1 1 1 2 2 2 2 Ketopantoate hydroxymethyltransferase PPR_1 PF12854.7 ORY39198.1 - 0.0044 16.7 0.2 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 PPR repeat PPR_2 PF13041.6 ORY39198.1 - 0.0072 16.5 0.0 7.2 6.9 0.0 3.9 4 0 0 4 4 4 1 PPR repeat family PPR PF01535.20 ORY39198.1 - 0.0095 16.1 0.0 0.53 10.7 0.0 3.1 3 0 0 3 3 3 1 PPR repeat DHBP_synthase PF00926.19 ORY39199.1 - 5.5e-56 189.1 0.0 6.1e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase DUF3450 PF11932.8 ORY39262.1 - 0.00075 18.9 1.4 0.00095 18.5 1.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) Nsp1_C PF05064.13 ORY39262.1 - 0.00097 18.9 1.2 0.0011 18.8 1.2 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region BLOC1_2 PF10046.9 ORY39262.1 - 0.0012 19.1 1.0 0.0016 18.7 1.0 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ZapB PF06005.12 ORY39262.1 - 0.0012 19.2 4.9 0.0017 18.8 5.0 1.3 1 1 0 1 1 1 1 Cell division protein ZapB GAS PF13851.6 ORY39262.1 - 0.0018 17.6 2.2 0.0021 17.4 2.2 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Spc29 PF17082.5 ORY39262.1 - 0.0029 17.5 1.0 0.0033 17.3 1.0 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 BST2 PF16716.5 ORY39262.1 - 0.0041 17.7 2.1 0.0052 17.3 2.1 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 Cluap1 PF10234.9 ORY39262.1 - 0.02 14.3 1.4 0.021 14.2 1.4 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 TMF_DNA_bd PF12329.8 ORY39262.1 - 0.02 14.9 2.3 0.02 14.9 2.3 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding HlyD_D23 PF16576.5 ORY39262.1 - 0.026 13.8 1.0 0.028 13.7 1.0 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion YabA PF06156.13 ORY39262.1 - 0.026 15.2 1.3 0.031 14.9 1.3 1.2 1 0 0 1 1 1 0 Initiation control protein YabA Tropomyosin_1 PF12718.7 ORY39262.1 - 0.031 14.4 2.7 0.044 13.9 2.7 1.4 1 1 0 1 1 1 0 Tropomyosin like Herpes_UL6 PF01763.16 ORY39262.1 - 0.032 12.8 1.6 0.032 12.8 1.6 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like APG6_N PF17675.1 ORY39262.1 - 0.036 14.6 2.8 0.048 14.2 2.8 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region BSP PF04450.12 ORY39262.1 - 0.037 13.8 0.0 0.055 13.3 0.0 1.3 1 1 0 1 1 1 0 Peptidase of plants and bacteria DUF948 PF06103.11 ORY39262.1 - 0.058 13.7 0.3 0.082 13.2 0.3 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.12 ORY39262.1 - 0.097 13.3 4.0 0.32 11.6 4.0 1.9 1 1 0 1 1 1 0 SlyX FliJ PF02050.16 ORY39262.1 - 0.13 12.5 5.9 1 9.6 3.0 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein Fib_alpha PF08702.10 ORY39262.1 - 0.15 12.3 3.3 0.47 10.6 3.2 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 ORY39262.1 - 0.2 12.2 2.3 0.82 10.2 2.4 1.9 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein XhlA PF10779.9 ORY39262.1 - 0.25 11.6 2.1 0.5 10.6 2.1 1.5 1 0 0 1 1 1 0 Haemolysin XhlA DivIC PF04977.15 ORY39262.1 - 0.32 10.8 3.5 0.79 9.5 3.5 1.8 1 1 0 1 1 1 0 Septum formation initiator FlaC_arch PF05377.11 ORY39262.1 - 0.37 11.2 3.7 1.8 9.0 0.3 2.3 1 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Asp PF00026.23 ORY39263.1 - 3e-23 82.7 0.6 2.4e-16 60.1 0.1 2.3 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 ORY39263.1 - 0.047 13.5 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal SdrG_C_C PF10425.9 ORY39263.1 - 0.094 12.8 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 C-terminus of bacterial fibrinogen-binding adhesin Transferase PF02458.15 ORY39264.1 - 0.022 13.4 0.1 0.041 12.5 0.1 1.4 1 0 0 1 1 1 0 Transferase family DUF885 PF05960.11 ORY39265.1 - 1.8e-109 367.8 0.0 1.9e-109 367.7 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) YfiO PF13525.6 ORY39265.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Outer membrane lipoprotein MMR_HSR1 PF01926.23 ORY39266.1 - 6.6e-05 23.0 0.3 0.00022 21.3 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase SHE3 PF17078.5 ORY39266.1 - 0.00054 19.7 13.1 0.00054 19.7 13.1 2.1 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 RsgA_GTPase PF03193.16 ORY39266.1 - 0.0039 17.1 0.2 0.0039 17.1 0.2 2.1 2 0 0 2 2 2 1 RsgA GTPase CENP-F_leu_zip PF10473.9 ORY39266.1 - 0.0051 16.8 16.7 0.0051 16.8 16.7 2.6 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_22 PF13401.6 ORY39266.1 - 0.013 15.8 1.8 0.063 13.6 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ORY39266.1 - 0.026 14.2 0.0 0.074 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY39266.1 - 0.031 14.6 0.3 0.18 12.2 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain Spc7 PF08317.11 ORY39266.1 - 0.1 11.4 26.1 0.13 11.2 18.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4934 PF16288.5 ORY39266.1 - 0.11 12.4 0.2 21 5.1 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4934) DUF3389 PF11869.8 ORY39266.1 - 0.29 11.3 1.5 9.6 6.5 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3389) SWIRM PF04433.17 ORY39266.1 - 0.33 11.3 2.0 0.61 10.5 1.1 2.0 1 1 0 1 1 1 0 SWIRM domain DivIC PF04977.15 ORY39266.1 - 0.37 10.6 17.4 2.4 8.0 7.4 3.6 1 1 2 3 3 3 0 Septum formation initiator Dynamin_N PF00350.23 ORY39266.1 - 0.44 10.6 0.0 0.44 10.6 0.0 3.4 4 1 0 4 4 4 0 Dynamin family DUF4200 PF13863.6 ORY39266.1 - 1.9 8.9 24.1 0.44 11.0 18.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) APG6_N PF17675.1 ORY39266.1 - 3 8.4 24.3 0.14 12.7 7.3 3.2 1 1 2 3 3 3 0 Apg6 coiled-coil region HALZ PF02183.18 ORY39266.1 - 3.1 8.1 13.3 26 5.1 1.3 4.0 3 1 1 4 4 4 0 Homeobox associated leucine zipper CENP-H PF05837.12 ORY39266.1 - 5.8 7.4 25.5 1 9.8 14.4 3.6 2 1 1 3 3 3 0 Centromere protein H (CENP-H) DUF3450 PF11932.8 ORY39266.1 - 8.3 5.6 20.4 0.41 9.9 4.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) ATG16 PF08614.11 ORY39266.1 - 9.2 6.4 22.7 1.5 9.0 17.7 2.1 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) RabGAP-TBC PF00566.18 ORY39267.1 - 2.5e-12 46.9 0.2 2e-11 43.9 0.2 2.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain FMO-like PF00743.19 ORY39269.1 - 8.4e-15 54.2 0.0 3.1e-13 49.0 0.0 2.4 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORY39269.1 - 1.5e-05 24.4 0.0 0.00019 20.8 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY39269.1 - 0.00012 21.4 0.0 0.00032 20.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY39269.1 - 0.00048 19.8 0.0 0.028 14.0 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 ORY39269.1 - 0.00081 18.6 0.0 0.0037 16.4 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 ORY39269.1 - 0.18 11.0 0.1 4.3 6.5 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain TIR_2 PF13676.6 ORY39270.1 - 1.8e-12 47.9 0.0 4.7e-06 27.2 0.0 2.5 2 1 0 2 2 2 2 TIR domain TIR PF01582.20 ORY39270.1 - 0.00029 20.7 0.0 0.26 11.0 0.0 2.6 2 1 0 2 2 2 2 TIR domain Peptidase_Mx1 PF15890.5 ORY39270.1 - 0.11 11.9 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase HBD PF18534.1 ORY39270.1 - 0.12 12.5 0.0 0.32 11.2 0.0 1.7 2 0 0 2 2 2 0 Helical bundle domain DUF1863 PF08937.11 ORY39270.1 - 0.15 12.4 0.0 2.2 8.6 0.1 2.4 2 1 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) GDI PF00996.18 ORY39271.1 - 1.1e-178 594.3 0.9 8.6e-145 482.6 0.2 2.0 1 1 1 2 2 2 2 GDP dissociation inhibitor Amino_oxidase PF01593.24 ORY39271.1 - 0.0058 16.0 0.0 0.0079 15.5 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase TFIIA PF03153.13 ORY39272.1 - 3.7 7.4 17.9 4.7 7.1 17.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA PF00004.29 ORY39273.1 - 5.1e-25 88.4 0.1 1.7e-24 86.7 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 ORY39273.1 - 4.4e-07 29.8 0.1 1.6e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 ORY39273.1 - 0.0018 18.1 0.1 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ORY39273.1 - 0.0024 17.9 0.2 0.1 12.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY39273.1 - 0.0036 17.7 0.1 0.0069 16.8 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 ORY39273.1 - 0.0097 15.1 0.0 0.025 13.8 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 ORY39273.1 - 0.018 14.4 0.2 0.053 12.9 0.2 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 ORY39273.1 - 0.019 15.2 0.1 0.029 14.7 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORY39273.1 - 0.12 12.5 0.1 0.2 11.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ORY39273.1 - 0.17 11.6 0.1 0.32 10.7 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Hydrolase PF00702.26 ORY39274.1 - 5.8e-12 46.4 3.4 4.6e-07 30.3 1.7 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORY39274.1 - 1.8e-11 43.9 0.0 6.4e-09 35.6 0.0 2.6 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase PF13246.6 ORY39274.1 - 8.7e-09 35.3 0.0 1.4e-07 31.5 0.0 2.7 1 1 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 ORY39274.1 - 2.3e-08 34.0 0.6 6.3e-08 32.5 0.0 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 ORY39274.1 - 1.8e-06 27.5 0.0 3.4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 ORY39274.1 - 0.0069 16.8 0.0 0.019 15.4 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORY39275.1 - 5.9e-32 110.6 0.4 5.9e-32 110.6 0.4 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY39275.1 - 1.5e-21 76.9 2.7 1.5e-21 76.9 2.7 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY39275.1 - 9.9e-07 29.2 0.1 1.6e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UPF0060 PF02694.15 ORY39275.1 - 0.023 14.9 0.5 0.088 13.0 0.5 2.0 1 0 0 1 1 1 0 Uncharacterised BCR, YnfA/UPF0060 family DUF1751 PF08551.10 ORY39275.1 - 0.042 14.4 0.2 0.22 12.1 0.2 2.2 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) Hydrolase_3 PF08282.12 ORY39275.1 - 0.071 12.8 0.9 0.15 11.8 0.0 1.9 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase bMG6 PF17962.1 ORY39275.1 - 0.08 13.1 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Bacterial macroglobulin domain 6 NADH_dh_m_C1 PF15088.6 ORY39275.1 - 0.14 11.7 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial TRAPP PF04051.16 ORY39277.1 - 1.4e-35 122.1 0.0 1.7e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ferritin_2 PF13668.6 ORY39277.1 - 0.15 12.3 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 Ferritin-like domain DUF5101 PF17031.5 ORY39278.1 - 0.12 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) SpoU_methylase PF00588.19 ORY39279.1 - 1.8e-21 76.8 0.0 3.2e-21 76.0 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family Lung_7-TM_R PF06814.13 ORY39280.1 - 7.1e-08 32.0 11.8 1.9e-06 27.3 6.1 2.3 2 0 0 2 2 2 2 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 ORY39280.1 - 0.019 14.4 5.2 0.031 13.7 5.2 1.3 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain CCDC53 PF10152.9 ORY39280.1 - 0.11 12.9 0.3 0.18 12.2 0.3 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex ALMT PF11744.8 ORY39280.1 - 0.48 9.2 1.9 11 4.7 0.5 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter ubiquitin PF00240.23 ORY39281.1 - 1.2e-137 447.9 19.3 8.6e-34 115.1 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 ORY39281.1 - 7.7e-64 211.5 19.7 1.9e-15 56.4 0.6 4.1 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORY39281.1 - 5.2e-24 84.5 10.1 0.00013 22.3 0.2 5.7 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 ORY39281.1 - 1.4e-15 57.0 4.5 0.031 14.2 0.1 4.3 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 ORY39281.1 - 1.1e-14 54.6 9.2 0.014 15.8 0.2 4.1 4 0 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORY39281.1 - 2.6e-14 53.2 3.7 0.097 12.8 0.0 5.1 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 ORY39281.1 - 2.2e-13 50.6 1.3 0.29 11.7 0.0 4.2 1 1 1 4 4 4 4 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 ORY39281.1 - 9.4e-11 41.8 0.5 0.74 9.6 0.0 4.1 1 1 3 4 4 4 4 Silencing defective 2 N-terminal ubiquitin domain Methyltrans_RNA PF04452.14 ORY39281.1 - 3.7e-07 29.7 1.0 0.85 8.9 0.0 3.4 3 0 0 3 3 3 3 RNA methyltransferase Ubiquitin_4 PF18036.1 ORY39281.1 - 8.8e-07 28.9 25.3 12 6.0 0.2 8.0 8 0 0 8 8 8 0 Ubiquitin-like domain DUF3861 PF12977.7 ORY39281.1 - 1.5e-06 28.3 3.2 8.9 6.6 0.0 4.3 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 ORY39281.1 - 8e-06 26.2 0.0 33 5.0 0.0 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) UDP-g_GGTase PF06427.11 ORY39281.1 - 1.7e-05 24.9 5.5 4.2 7.5 0.1 4.2 4 0 0 4 4 4 3 UDP-glucose:Glycoprotein Glucosyltransferase Big_7 PF17957.1 ORY39281.1 - 3.3e-05 24.6 0.1 48 4.8 0.0 4.2 4 0 0 4 4 4 0 Bacterial Ig domain ACT_5 PF13710.6 ORY39281.1 - 6.1e-05 22.8 4.7 16 5.5 0.0 4.3 4 0 0 4 4 4 0 ACT domain ACT_4 PF13291.6 ORY39281.1 - 0.00023 21.7 1.5 50 4.6 0.0 4.3 4 0 0 4 4 4 0 ACT domain DUF969 PF06149.12 ORY39281.1 - 0.00041 19.8 0.0 23 4.3 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF969) ORF11CD3 PF10549.9 ORY39281.1 - 0.0065 16.6 0.0 1e+02 3.2 0.0 4.6 4 0 0 4 4 4 0 ORF11CD3 domain ProRS-C_2 PF09181.10 ORY39281.1 - 0.017 15.2 6.4 59 3.9 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal DUF493 PF04359.14 ORY39281.1 - 0.039 14.5 0.1 2.8e+02 2.2 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF493) Tash_PEST PF07708.11 ORY39281.1 - 0.18 12.0 27.2 6.8 7.0 1.4 4.4 4 0 0 4 4 4 0 Tash protein PEST motif YcgR_2 PF12945.7 ORY39281.1 - 0.19 11.9 4.9 1.4e+02 2.7 0.1 4.1 4 0 0 4 4 4 0 Flagellar protein YcgR Phage_sheath_1N PF17481.2 ORY39281.1 - 0.32 11.5 8.4 51 4.4 1.3 4.0 1 1 1 2 2 2 0 Phage tail sheath protein beta-sandwich domain Plexin_cytopl PF08337.12 ORY39281.1 - 0.61 8.7 15.7 10 4.7 0.2 4.9 4 3 0 4 4 4 0 Plexin cytoplasmic RasGAP domain FlgD_ig PF13860.6 ORY39281.1 - 1 9.3 8.7 1.1e+02 2.8 0.1 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain PI3K_p85B PF02192.16 ORY39281.1 - 1.8 8.3 9.6 91 2.9 0.1 4.3 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain TIM21 PF08294.11 ORY39282.1 - 5.8e-16 58.7 0.0 7.1e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 TIM21 HIG_1_N PF04588.13 ORY39283.1 - 0.013 15.7 0.2 0.024 14.8 0.2 1.5 1 0 0 1 1 1 0 Hypoxia induced protein conserved region ENOD93 PF03386.14 ORY39284.1 - 0.075 12.9 0.4 0.075 12.9 0.4 1.6 2 0 0 2 2 2 0 Early nodulin 93 ENOD93 protein SH3_9 PF14604.6 ORY39286.1 - 1.4e-18 66.4 0.1 1.6e-08 34.2 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 ORY39286.1 - 2.7e-18 65.3 0.1 1.6e-09 37.2 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 ORY39286.1 - 4.1e-16 58.4 0.0 2.9e-08 33.2 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain Amidohydro_1 PF01979.20 ORY39287.1 - 1.5e-22 80.4 0.1 2.4e-22 79.8 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY39287.1 - 2.9e-08 33.6 0.1 1.7e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase family DUF1897 PF09005.10 ORY39289.1 - 5.9e-06 25.7 1.3 1.2e-05 24.7 1.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1897) SARAF PF06682.12 ORY39289.1 - 0.045 13.4 0.1 0.052 13.2 0.1 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Saf_2TM PF18303.1 ORY39289.1 - 0.17 11.4 0.1 0.23 11.0 0.1 1.1 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain PRMT5 PF05185.16 ORY39289.1 - 0.8 9.5 2.1 4.2 7.2 1.6 1.9 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase AAA_22 PF13401.6 ORY39291.1 - 0.00098 19.4 0.0 0.008 16.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY39291.1 - 0.01 16.2 0.0 0.028 14.8 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain ResIII PF04851.15 ORY39291.1 - 0.038 14.0 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1925 PF09094.11 ORY39291.1 - 0.16 12.3 0.0 0.36 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1925) AAA_5 PF07728.14 ORY39292.1 - 9.8e-78 258.8 0.0 2e-29 102.4 0.0 3.4 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) CbbQ_C PF08406.10 ORY39292.1 - 2.9e-06 27.5 0.0 0.0096 16.2 0.0 2.7 2 0 0 2 2 2 2 CbbQ/NirQ/NorQ C-terminal AAA_22 PF13401.6 ORY39292.1 - 0.00029 21.1 1.4 3.1 8.1 0.1 4.2 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 ORY39292.1 - 0.0006 20.2 0.7 0.89 9.9 0.0 3.6 3 1 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.27 ORY39292.1 - 0.011 16.3 0.0 1.8 9.1 0.0 2.9 2 0 0 2 2 2 0 ABC transporter AAA_3 PF07726.11 ORY39292.1 - 0.029 14.2 0.0 6.6 6.6 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ORY39292.1 - 0.032 13.7 0.0 9.5 5.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 ORY39292.1 - 0.042 13.2 0.3 3.3 7.0 0.0 3.2 3 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_lid_7 PF17867.1 ORY39292.1 - 0.095 12.9 0.0 0.45 10.7 0.0 2.1 2 0 0 2 2 2 0 Midasin AAA lid domain AAA_29 PF13555.6 ORY39292.1 - 0.098 12.4 0.0 9.2 6.1 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain MCM PF00493.23 ORY39292.1 - 0.16 11.1 0.0 0.4 9.7 0.0 1.6 1 0 0 1 1 1 0 MCM P-loop domain AAA_22 PF13401.6 ORY39293.1 - 0.00071 19.9 0.0 0.0037 17.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 ORY39293.1 - 0.021 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 ORY39293.1 - 0.023 15.1 0.0 0.045 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Plus-3 PF03126.18 ORY39294.1 - 8.2e-19 68.1 0.2 2.9e-18 66.4 0.2 2.0 1 1 0 1 1 1 1 Plus-3 domain Peptidase_M3_N PF08439.10 ORY39294.1 - 0.038 14.3 2.3 0.14 12.4 0.2 2.8 1 1 1 2 2 2 0 Oligopeptidase F CorA PF01544.18 ORY39294.1 - 1.1 8.4 11.4 0.031 13.6 5.0 1.6 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Plavaka PF18759.1 ORY39295.1 - 4e-20 72.3 0.0 7.1e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase NADHdh-2_N PF12155.8 ORY39297.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 N-terminal TPR_2 PF07719.17 ORY39298.1 - 0.012 15.7 0.4 2.2 8.6 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY39298.1 - 0.024 15.4 0.2 2.6 9.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY39298.1 - 0.025 14.4 0.5 10 6.1 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TFIIF_alpha PF05793.12 ORY39299.1 - 1.9 7.0 3.2 2.9 6.4 3.3 1.4 1 1 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MNR PF15718.5 ORY39300.1 - 0.033 12.3 2.9 0.036 12.2 2.9 1.0 1 0 0 1 1 1 0 Protein moonraker PRP38_assoc PF12871.7 ORY39303.1 - 0.18 12.4 8.3 0.44 11.2 8.3 1.6 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Tub_N PF16322.5 ORY39303.1 - 0.59 10.5 7.8 0.67 10.3 7.8 1.3 1 1 0 1 1 1 0 Tubby N-terminal HflK_N PF12221.8 ORY39305.1 - 0.12 12.4 0.0 0.35 10.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial membrane protein N terminal Kelch_5 PF13854.6 ORY39306.1 - 2e-22 78.7 2.1 0.001 19.0 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 ORY39306.1 - 5e-19 67.9 2.6 0.0064 16.8 0.0 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 ORY39306.1 - 2.9e-18 65.6 9.5 0.008 16.2 0.1 7.0 6 1 1 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY39306.1 - 4.1e-17 61.4 3.7 0.00077 19.3 0.0 6.6 6 1 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 ORY39306.1 - 2.5e-15 56.3 8.5 0.002 18.4 0.0 7.4 7 2 0 7 7 7 3 Galactose oxidase, central domain Kelch_1 PF01344.25 ORY39306.1 - 4.1e-15 55.1 7.1 0.00086 18.8 0.0 6.7 7 1 0 7 7 7 4 Kelch motif zf-MYND PF01753.18 ORY39306.1 - 1.5e-11 44.2 13.1 2.7e-11 43.4 13.1 1.4 1 0 0 1 1 1 1 MYND finger RAG2 PF03089.14 ORY39306.1 - 0.041 12.9 0.0 0.15 11.0 0.0 1.9 2 0 0 2 2 2 0 Recombination activating protein 2 DUF296 PF03479.15 ORY39306.1 - 0.16 12.4 0.0 0.43 11.0 0.0 1.7 1 1 0 1 1 1 0 Plants and Prokaryotes Conserved (PCC) domain zf-C6H2 PF15801.5 ORY39306.1 - 4.3 7.7 11.6 8.5 6.8 11.6 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PolC_DP2 PF03833.13 ORY39306.1 - 8 4.2 5.7 12 3.6 5.7 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 TPR_MLP1_2 PF07926.12 ORY39307.1 - 0.048 13.7 1.4 0.064 13.3 1.4 1.2 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Peptidase_M28 PF04389.17 ORY39309.1 - 1.5e-15 57.4 0.0 4.2e-07 29.8 0.0 2.4 1 1 1 2 2 2 2 Peptidase family M28 ZNRF_3_ecto PF18212.1 ORY39309.1 - 0.028 14.4 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 ZNRF-3 Ectodomain DUF4097 PF13349.6 ORY39310.1 - 0.00016 21.1 5.9 0.0003 20.2 5.9 1.4 1 0 0 1 1 1 1 Putative adhesin Peptidase_S9 PF00326.21 ORY39311.1 - 1.9e-25 89.6 0.0 1.6e-12 47.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 ORY39311.1 - 2.7e-07 30.4 0.0 2.3e-06 27.3 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 ORY39311.1 - 0.00063 19.4 0.0 0.17 11.4 0.0 2.2 2 0 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 ORY39311.1 - 0.096 11.9 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Phtf-FEM1B_bdg PF12129.8 ORY39312.1 - 8.5 6.2 8.0 25 4.7 0.0 2.7 3 0 0 3 3 3 0 Male germ-cell putative homeodomain transcription factor Glyco_trans_1_3 PF13528.6 ORY39314.1 - 0.12 11.6 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 1 zf-C2HC_2 PF13913.6 ORY39315.1 - 3.5e-17 61.8 5.9 2.7e-08 33.5 1.8 2.4 2 0 0 2 2 2 2 zinc-finger of a C2HC-type Sgf11 PF08209.11 ORY39315.1 - 0.00024 20.6 3.7 0.052 13.1 0.4 2.8 2 0 0 2 2 2 2 Sgf11 (transcriptional regulation protein) DZR PF12773.7 ORY39315.1 - 0.0019 18.1 0.5 0.0019 18.1 0.5 3.1 2 1 1 3 3 3 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 ORY39315.1 - 0.0063 16.2 13.4 0.0068 16.1 2.8 3.8 3 1 0 3 3 3 1 zinc-ribbon domain Rad50_zn_hook PF04423.14 ORY39315.1 - 0.055 13.3 1.4 0.19 11.6 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zinc_ribbon_15 PF17032.5 ORY39315.1 - 0.065 14.0 7.5 0.1 13.4 0.3 2.7 2 1 0 2 2 2 0 zinc-ribbon family Elf1 PF05129.13 ORY39315.1 - 0.12 12.4 1.5 8.5 6.5 0.0 3.1 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like zf-C2H2_4 PF13894.6 ORY39315.1 - 0.17 12.8 2.3 9.5 7.4 0.5 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger NinF PF05810.12 ORY39315.1 - 0.33 10.9 5.0 4.4 7.2 0.7 2.6 2 0 0 2 2 2 0 NinF protein DUF2318 PF10080.9 ORY39315.1 - 0.71 10.0 0.0 0.71 10.0 0.0 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) HypA PF01155.19 ORY39315.1 - 2.5 8.2 10.2 4 7.5 0.1 3.1 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RNA_POL_M_15KD PF02150.16 ORY39315.1 - 3.6 7.5 10.9 10 6.1 0.2 3.3 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-ribbon_3 PF13248.6 ORY39315.1 - 3.7 7.1 11.9 0.38 10.2 2.6 3.3 3 1 0 3 3 3 0 zinc-ribbon domain zf-C2H2_11 PF16622.5 ORY39315.1 - 4 7.3 10.8 6.9 6.5 0.1 3.9 4 0 0 4 4 4 0 zinc-finger C2H2-type DUF202 PF02656.15 ORY39316.1 - 2.9e-15 56.5 1.2 3.2e-15 56.3 0.4 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Pex14_N PF04695.13 ORY39316.1 - 0.023 15.3 0.1 0.023 15.3 0.1 1.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LptF_LptG PF03739.14 ORY39316.1 - 0.073 11.9 0.0 0.093 11.6 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG YiaAB PF05360.14 ORY39316.1 - 0.075 13.3 2.9 0.13 12.5 2.9 1.4 1 0 0 1 1 1 0 yiaA/B two helix domain DNA_methylase PF00145.17 ORY39317.1 - 0.017 14.5 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase FBP_C PF16571.5 ORY39317.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 FBP C-terminal treble-clef zinc-finger Dppa2_A PF14049.6 ORY39317.1 - 0.2 11.8 4.2 28 4.9 0.0 4.0 3 0 0 3 3 3 0 Dppa2/4 conserved region in higher vertebrates Hydrolase_4 PF12146.8 ORY39318.1 - 4.4e-52 176.7 0.1 5.1e-52 176.5 0.1 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY39318.1 - 7.4e-08 33.3 0.0 9e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY39318.1 - 7.6e-06 25.7 0.1 1.5e-05 24.8 0.0 1.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 ORY39318.1 - 0.0031 17.2 0.0 0.0047 16.6 0.0 1.4 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 ORY39318.1 - 0.0072 15.8 0.1 0.76 9.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Thioesterase PF00975.20 ORY39318.1 - 0.0073 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain AXE1 PF05448.12 ORY39318.1 - 0.0088 14.8 0.3 0.023 13.4 0.3 1.7 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) PGAP1 PF07819.13 ORY39318.1 - 0.037 13.7 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein CDC14 PF08045.11 ORY39319.1 - 3.9e-19 68.9 2.0 5.5e-19 68.3 2.0 1.2 1 0 0 1 1 1 1 Cell division control protein 14, SIN component DUF3361 PF11841.8 ORY39319.1 - 0.078 12.9 0.4 0.64 9.9 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3361) Orbi_NS3 PF01616.16 ORY39319.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Orbivirus NS3 tRNA_edit PF04073.15 ORY39320.1 - 6e-11 42.5 0.0 1.3e-10 41.4 0.0 1.5 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain Bep_C_terminal PF17841.1 ORY39320.1 - 0.082 13.1 0.4 0.15 12.3 0.4 1.3 1 0 0 1 1 1 0 BID domain of Bartonella effector protein (Bep) Exo_endo_phos PF03372.23 ORY39321.1 - 2.1e-06 27.4 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family TPR_1 PF00515.28 ORY39322.1 - 1.8e-27 94.0 0.1 5.2e-06 26.0 0.3 8.1 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.17 ORY39322.1 - 2.2e-27 92.9 0.1 6e-07 29.1 0.1 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORY39322.1 - 4.7e-19 66.9 0.9 0.00016 21.7 0.0 7.5 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 ORY39322.1 - 3.9e-13 49.8 0.0 0.017 15.7 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORY39322.1 - 2.4e-12 47.0 2.9 3.6e-05 24.0 0.0 6.4 6 2 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY39322.1 - 6.5e-12 45.5 4.5 2.1e-05 24.7 0.1 4.2 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 ORY39322.1 - 6.9e-12 45.1 0.0 0.0079 16.9 0.0 7.2 6 2 2 8 8 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY39322.1 - 5.1e-11 42.1 0.0 0.15 11.8 0.0 5.8 4 1 1 5 5 5 4 TPR repeat TPR_7 PF13176.6 ORY39322.1 - 1.8e-10 40.1 0.7 0.0014 18.6 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY39322.1 - 6.3e-08 32.5 1.0 0.0021 18.3 0.0 5.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 ORY39322.1 - 1.2e-05 24.7 0.0 0.21 10.7 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY39322.1 - 5.5e-05 23.6 0.0 0.013 15.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORY39322.1 - 6.6e-05 23.0 0.0 0.0022 18.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 ORY39322.1 - 7e-05 23.1 3.0 1.4 9.8 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORY39322.1 - 0.00018 21.2 1.2 4.5 7.3 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY39322.1 - 0.00073 20.0 0.2 27 5.7 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY39322.1 - 0.026 14.6 0.7 4.8 7.3 0.0 3.2 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Pept_tRNA_hydro PF01195.19 ORY39324.1 - 2.7e-43 147.9 0.0 3.6e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase zf-RING_11 PF17123.5 ORY39327.1 - 3.5e-08 33.1 0.6 6.5e-08 32.2 0.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 ORY39327.1 - 5.5e-05 23.4 1.4 0.0001 22.6 1.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY39327.1 - 0.0025 17.8 0.6 0.0059 16.6 0.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY39327.1 - 0.013 15.4 0.3 0.027 14.3 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ADH_zinc_N PF00107.26 ORY39334.1 - 2.2e-15 56.8 0.1 5.9e-15 55.4 0.1 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY39334.1 - 1.2e-05 25.1 0.0 3.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Septin PF00735.18 ORY39335.1 - 7.3e-115 383.1 0.3 7.3e-115 383.1 0.3 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 ORY39335.1 - 6.1e-10 39.2 1.7 6.3e-10 39.1 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY39335.1 - 2.5e-07 30.7 6.1 4.4e-06 26.7 0.1 2.9 3 0 0 3 3 3 1 RsgA GTPase GTP_EFTU PF00009.27 ORY39335.1 - 6.4e-06 25.8 0.1 6.4e-06 25.8 0.1 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 ORY39335.1 - 0.00014 22.0 4.9 0.063 13.3 0.0 3.5 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.16 ORY39335.1 - 0.00045 19.6 0.0 0.00045 19.6 0.0 2.1 2 0 0 2 2 2 1 AIG1 family AAA_24 PF13479.6 ORY39335.1 - 0.0011 18.7 0.0 0.003 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 ORY39335.1 - 0.0012 19.0 0.0 0.0056 16.9 0.0 2.2 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 ORY39335.1 - 0.0013 19.0 0.7 0.013 15.8 0.0 2.8 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.27 ORY39335.1 - 0.0014 19.1 0.5 0.0014 19.1 0.5 2.5 2 1 0 2 2 2 1 ABC transporter Ras PF00071.22 ORY39335.1 - 0.0025 17.4 1.0 0.022 14.4 0.3 2.8 3 1 0 3 3 2 1 Ras family AAA_16 PF13191.6 ORY39335.1 - 0.0043 17.4 0.1 0.013 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain TSNAXIP1_N PF15739.5 ORY39335.1 - 0.0047 17.3 0.0 0.0047 17.3 0.0 3.1 2 1 1 3 3 2 1 Translin-associated factor X-interacting N-terminus AAA_29 PF13555.6 ORY39335.1 - 0.0093 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain KAP_NTPase PF07693.14 ORY39335.1 - 0.1 11.8 2.9 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain HAUS6_N PF14661.6 ORY39335.1 - 0.12 11.9 9.4 0.22 11.1 9.4 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus NuiA PF07924.11 ORY39335.1 - 0.13 12.6 4.8 0.31 11.4 4.8 1.6 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein TFIIF_beta_N PF17683.1 ORY39335.1 - 0.19 12.4 4.1 0.2 12.3 2.7 1.8 2 0 0 2 2 1 0 TFIIF, beta subunit N-terminus IIGP PF05049.13 ORY39335.1 - 0.22 10.5 0.0 0.22 10.5 0.0 3.0 4 1 0 4 4 4 0 Interferon-inducible GTPase (IIGP) SRPRB PF09439.10 ORY39335.1 - 0.32 10.4 0.0 0.32 10.4 0.0 2.7 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit AAA_23 PF13476.6 ORY39335.1 - 1.3 9.5 23.0 4.1e+02 1.3 23.0 2.3 1 1 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 ORY39335.1 - 1.4 8.4 10.4 2.6 7.5 10.4 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Strep_SA_rep PF06696.11 ORY39335.1 - 6.6 6.9 10.5 0.15 12.1 1.6 2.4 2 0 0 2 2 2 0 Streptococcal surface antigen repeat Atg14 PF10186.9 ORY39335.1 - 9.3 5.2 12.8 16 4.4 12.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1681 PF07933.14 ORY39336.1 - 1.3e-45 154.8 0.0 1.4e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) AATase PF07247.12 ORY39337.1 - 0.0025 16.5 0.0 0.0033 16.1 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase DUF126 PF01989.16 ORY39337.1 - 0.08 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Aconitase X swivel domain Acyltransferase PF01553.21 ORY39340.1 - 9.9e-08 31.7 0.4 2.9e-07 30.2 0.4 1.7 1 1 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 ORY39340.1 - 3.2e-07 29.6 0.0 5.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Nup54_C PF18437.1 ORY39340.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain Rad9 PF04139.13 ORY39341.1 - 6.8e-57 192.8 0.0 1e-56 192.2 0.0 1.2 1 0 0 1 1 1 1 Rad9 DUF773 PF05600.12 ORY39341.1 - 0.21 10.3 3.5 0.32 9.7 3.5 1.2 1 0 0 1 1 1 0 CDK5 regulatory subunit-associated protein 3 Ribosomal_60s PF00428.19 ORY39341.1 - 1.4 9.6 9.7 8.6 7.0 9.7 2.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein Myb_DNA-binding PF00249.31 ORY39342.1 - 0.005 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Sulfotransfer_3 PF13469.6 ORY39344.1 - 2.9e-20 73.6 0.0 1.9e-19 71.0 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase family ubiquitin PF00240.23 ORY39345.1 - 1.6e-171 556.4 26.1 1.1e-33 114.8 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 ORY39345.1 - 8.9e-80 262.5 26.6 2.5e-15 56.1 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORY39345.1 - 2.5e-29 101.6 13.6 0.00035 21.0 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 ORY39345.1 - 4.7e-19 68.1 7.1 0.047 13.6 0.0 5.2 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORY39345.1 - 1.8e-17 63.4 5.5 0.15 12.2 0.0 6.0 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 ORY39345.1 - 2.4e-17 63.1 13.2 0.054 13.9 0.1 5.1 5 0 0 5 5 5 5 Ubiquitin-like domain DUF2407 PF10302.9 ORY39345.1 - 1.1e-16 61.2 2.3 0.34 11.5 0.0 5.2 1 1 4 5 5 5 5 DUF2407 ubiquitin-like domain Methyltrans_RNA PF04452.14 ORY39345.1 - 2.2e-09 37.0 2.7 1.1 8.6 0.0 4.3 4 0 0 4 4 4 4 RNA methyltransferase Ubiquitin_4 PF18036.1 ORY39345.1 - 2.8e-08 33.7 33.1 15 5.7 0.2 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain DUF3861 PF12977.7 ORY39345.1 - 7e-08 32.5 5.4 12 6.1 0.0 5.2 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) DUF2870 PF11069.8 ORY39345.1 - 1.8e-07 31.5 0.0 40 4.7 0.0 5.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) Big_7 PF17957.1 ORY39345.1 - 1.1e-06 29.3 0.2 63 4.4 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 ORY39345.1 - 2.4e-06 27.6 9.0 5.3 7.2 0.1 5.0 5 0 0 5 5 5 4 UDP-glucose:Glycoprotein Glucosyltransferase ACT_5 PF13710.6 ORY39345.1 - 6.3e-06 25.9 7.2 19 5.2 0.0 5.3 5 0 0 5 5 5 0 ACT domain ACT_4 PF13291.6 ORY39345.1 - 1.5e-05 25.5 1.9 76 4.0 0.0 5.2 5 0 0 5 5 5 0 ACT domain DUF969 PF06149.12 ORY39345.1 - 2.1e-05 24.0 0.1 29 4.0 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF969) ORF11CD3 PF10549.9 ORY39345.1 - 0.00045 20.3 0.0 1.2e+02 2.9 0.0 5.5 5 0 0 5 5 5 0 ORF11CD3 domain DUF493 PF04359.14 ORY39345.1 - 0.0064 17.1 0.2 3.3e+02 1.9 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF493) ProRS-C_2 PF09181.10 ORY39345.1 - 0.0095 16.0 9.9 72 3.6 0.1 5.1 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 ORY39345.1 - 0.18 12.0 36.0 8 6.8 1.4 5.4 5 0 0 5 5 5 0 Tash protein PEST motif YcgR_2 PF12945.7 ORY39345.1 - 0.19 11.9 8.1 1.7e+02 2.4 0.1 5.0 5 0 0 5 5 5 0 Flagellar protein YcgR Phage_sheath_1N PF17481.2 ORY39345.1 - 0.22 12.0 10.7 1.3e+02 3.1 0.1 4.8 1 1 1 2 2 2 0 Phage tail sheath protein beta-sandwich domain FlgD_ig PF13860.6 ORY39345.1 - 1.8 8.5 12.8 1.3e+02 2.5 0.1 5.2 5 0 0 5 5 5 0 FlgD Ig-like domain PI3K_p85B PF02192.16 ORY39345.1 - 3.9 7.3 14.0 1.1e+02 2.7 0.1 5.1 5 0 0 5 5 5 0 PI3-kinase family, p85-binding domain LSM PF01423.22 ORY39346.1 - 1.5e-14 53.4 1.3 1.5e-14 53.4 1.3 1.4 2 0 0 2 2 2 1 LSM domain Man-6-P_recep PF02157.15 ORY39347.1 - 0.058 12.5 0.5 0.079 12.0 0.5 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate receptor Glycos_transf_2 PF00535.26 ORY39348.1 - 4.7e-17 62.3 0.0 9.1e-08 32.1 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glycos_transf_1 PF00534.20 ORY39348.1 - 1.2e-10 41.2 0.0 3.5e-10 39.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY39348.1 - 3.5e-10 40.4 0.0 1.9e-09 38.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_tranf_2_2 PF10111.9 ORY39348.1 - 3.3e-08 33.4 0.0 0.01 15.3 0.0 3.4 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 ORY39348.1 - 0.018 14.9 0.0 2.8 7.8 0.0 2.7 3 0 0 3 3 3 0 Glycosyltransferase like family 2 DUF2034 PF10356.9 ORY39349.1 - 2.1e-12 46.8 0.5 1.1e-06 28.2 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 ORY39349.1 - 1.9e-07 31.1 0.0 2.9e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease Ribosomal_S10 PF00338.22 ORY39350.1 - 2.7e-19 69.2 0.1 2.9e-19 69.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-CDGSH PF09360.10 ORY39352.1 - 3.3e-16 59.2 1.8 3.1e-08 33.7 0.1 2.3 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type Sulfatase PF00884.23 ORY39353.1 - 1.9e-57 195.0 0.4 2.4e-57 194.7 0.4 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 ORY39353.1 - 2.4e-06 27.8 0.0 5.6e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) PET10 PF17316.2 ORY39353.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Petite colonies protein 10 D123 PF07065.14 ORY39354.1 - 5.7e-108 360.7 0.0 6.5e-108 360.5 0.0 1.0 1 0 0 1 1 1 1 D123 Phage-tail_2 PF09096.10 ORY39354.1 - 0.13 12.2 0.1 0.21 11.5 0.1 1.2 1 0 0 1 1 1 0 Baseplate structural protein, domain 2 Transket_pyr PF02779.24 ORY39355.1 - 4e-64 215.5 0.0 6.4e-64 214.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 ORY39355.1 - 2.3e-61 207.4 0.0 3.6e-61 206.7 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 ORY39355.1 - 6.3e-36 123.4 0.0 8.9e-33 113.1 0.0 3.2 2 1 0 2 2 2 2 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 ORY39355.1 - 3.9e-19 67.9 0.4 8e-19 66.9 0.4 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus KASH_CCD PF14662.6 ORY39356.1 - 0.00051 19.9 15.4 0.0009 19.1 15.4 1.3 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 ORY39356.1 - 0.00076 18.5 15.3 0.0009 18.2 15.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein FlaC_arch PF05377.11 ORY39356.1 - 0.0011 19.4 12.4 0.41 11.1 1.2 3.5 2 2 1 3 3 3 2 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 ORY39356.1 - 0.0018 17.7 9.6 0.0021 17.5 9.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) SKA2 PF16740.5 ORY39356.1 - 0.004 16.9 10.2 0.091 12.5 1.5 2.0 1 1 1 2 2 2 2 Spindle and kinetochore-associated protein 2 CENP-F_leu_zip PF10473.9 ORY39356.1 - 0.0055 16.7 17.3 0.036 14.1 9.1 2.1 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mod_r PF07200.13 ORY39356.1 - 0.0064 16.6 15.4 0.032 14.3 14.3 1.9 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Spectrin PF00435.21 ORY39356.1 - 0.0079 16.7 13.1 0.17 12.4 1.3 2.2 1 1 1 2 2 2 2 Spectrin repeat Lebercilin PF15619.6 ORY39356.1 - 0.0079 15.9 18.0 0.01 15.5 18.0 1.1 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease EzrA PF06160.12 ORY39356.1 - 0.0093 14.2 11.2 0.0086 14.3 10.4 1.3 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA DMPK_coil PF08826.10 ORY39356.1 - 0.011 15.9 3.9 0.011 15.9 3.9 3.1 1 1 2 3 3 3 0 DMPK coiled coil domain like Fzo_mitofusin PF04799.13 ORY39356.1 - 0.012 15.2 10.5 0.21 11.1 2.1 2.1 1 1 1 2 2 2 0 fzo-like conserved region Med9 PF07544.13 ORY39356.1 - 0.014 15.5 10.4 0.077 13.1 10.0 2.3 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 TMF_DNA_bd PF12329.8 ORY39356.1 - 0.016 15.2 19.8 0.59 10.2 0.8 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.12 ORY39356.1 - 0.017 15.2 14.3 0.04 14.0 11.2 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 ORY39356.1 - 0.018 14.8 17.8 0.15 11.9 1.0 3.1 2 1 1 3 3 3 0 Septum formation initiator HAP1_N PF04849.13 ORY39356.1 - 0.019 14.2 12.8 0.44 9.7 7.1 2.0 1 1 1 2 2 2 0 HAP1 N-terminal conserved region TolA_bind_tri PF16331.5 ORY39356.1 - 0.033 14.3 12.8 0.86 9.7 0.8 3.0 1 1 2 3 3 3 0 TolA binding protein trimerisation Ax_dynein_light PF10211.9 ORY39356.1 - 0.034 14.1 14.2 0.68 9.9 7.2 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain DUF489 PF04356.12 ORY39356.1 - 0.034 14.1 5.2 0.021 14.8 3.2 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF489) JIP_LZII PF16471.5 ORY39356.1 - 0.039 14.1 15.4 0.38 10.9 1.7 3.3 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II HMMR_N PF15905.5 ORY39356.1 - 0.04 13.4 15.1 0.18 11.2 14.9 1.6 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal HOOK PF05622.12 ORY39356.1 - 0.042 12.0 14.2 0.049 11.8 14.2 1.0 1 0 0 1 1 1 0 HOOK protein ATG16 PF08614.11 ORY39356.1 - 0.045 14.0 18.2 0.18 12.0 18.2 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DivIVA PF05103.13 ORY39356.1 - 0.048 13.7 13.8 0.2 11.8 13.8 2.1 1 1 0 1 1 1 0 DivIVA protein Phage_GP20 PF06810.11 ORY39356.1 - 0.06 13.1 17.3 0.24 11.2 7.1 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 THOC7 PF05615.13 ORY39356.1 - 0.062 13.6 11.8 0.19 12.0 11.8 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 Intimin_C PF07979.11 ORY39356.1 - 0.07 13.6 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Intimin C-type lectin domain Gp58 PF07902.11 ORY39356.1 - 0.083 11.2 6.8 0.1 10.9 6.8 1.0 1 0 0 1 1 1 0 gp58-like protein DUF1664 PF07889.12 ORY39356.1 - 0.088 12.9 10.5 0.22 11.6 6.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Snapin_Pallidin PF14712.6 ORY39356.1 - 0.089 13.2 14.5 0.73 10.3 7.5 2.8 1 1 2 3 3 3 0 Snapin/Pallidin Golgin_A5 PF09787.9 ORY39356.1 - 0.096 12.1 14.9 0.1 12.0 14.9 1.0 1 0 0 1 1 1 0 Golgin subfamily A member 5 AAA_13 PF13166.6 ORY39356.1 - 0.097 11.3 11.0 0.11 11.1 11.0 1.1 1 0 0 1 1 1 0 AAA domain YabA PF06156.13 ORY39356.1 - 0.099 13.3 11.2 0.11 13.2 6.2 2.1 1 1 0 2 2 2 0 Initiation control protein YabA UPF0449 PF15136.6 ORY39356.1 - 0.1 13.1 0.6 0.1 13.1 0.6 2.9 1 1 2 3 3 3 0 Uncharacterised protein family UPF0449 Prefoldin PF02996.17 ORY39356.1 - 0.11 12.5 14.3 0.49 10.3 1.5 3.2 2 1 1 3 3 3 0 Prefoldin subunit Exonuc_VII_L PF02601.15 ORY39356.1 - 0.11 12.0 8.8 0.13 11.8 8.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Imm7 PF15585.6 ORY39356.1 - 0.13 12.5 4.5 0.13 12.5 1.4 2.1 1 1 1 2 2 2 0 Immunity protein 7 MtrB PF05440.12 ORY39356.1 - 0.13 12.7 3.0 11 6.5 0.1 2.9 1 1 2 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF3584 PF12128.8 ORY39356.1 - 0.14 9.7 13.1 0.16 9.5 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fez1 PF06818.15 ORY39356.1 - 0.15 12.5 13.7 0.4 11.1 8.8 1.6 1 1 0 1 1 1 0 Fez1 TFR_dimer PF04253.15 ORY39356.1 - 0.16 12.1 3.1 0.62 10.2 3.1 2.0 1 1 0 1 1 1 0 Transferrin receptor-like dimerisation domain HIP1_clath_bdg PF16515.5 ORY39356.1 - 0.17 12.5 16.7 4.2 8.1 4.4 2.9 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FadA PF09403.10 ORY39356.1 - 0.2 12.2 11.0 1 9.9 0.3 2.1 1 1 1 2 2 2 0 Adhesion protein FadA DUF745 PF05335.13 ORY39356.1 - 0.2 11.4 8.6 0.24 11.1 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Prefoldin_2 PF01920.20 ORY39356.1 - 0.21 11.6 16.0 1.9 8.5 0.6 3.1 1 1 2 3 3 3 0 Prefoldin subunit Apolipoprotein PF01442.18 ORY39356.1 - 0.24 11.3 14.1 0.88 9.4 13.6 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain LPP PF04728.13 ORY39356.1 - 0.29 11.6 11.2 34 4.9 7.4 3.2 2 1 0 2 2 2 0 Lipoprotein leucine-zipper Fungal_TACC PF12709.7 ORY39356.1 - 0.29 11.6 12.1 0.8 10.2 0.2 3.2 1 1 2 3 3 3 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF3450 PF11932.8 ORY39356.1 - 0.34 10.2 13.7 1.9 7.7 9.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Atg14 PF10186.9 ORY39356.1 - 0.39 9.7 12.5 0.48 9.5 12.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-H PF05837.12 ORY39356.1 - 0.41 11.1 15.7 0.57 10.6 10.3 2.1 1 1 1 2 2 2 0 Centromere protein H (CENP-H) ADIP PF11559.8 ORY39356.1 - 0.41 10.7 19.4 0.9 9.6 11.1 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMPIT PF07851.13 ORY39356.1 - 0.51 9.5 9.8 1.4 8.1 9.8 1.7 1 1 0 1 1 1 0 TMPIT-like protein DUF948 PF06103.11 ORY39356.1 - 0.52 10.6 9.8 3.4 8.0 0.2 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Latarcin PF10279.9 ORY39356.1 - 0.56 10.6 7.4 0.82 10.1 4.7 2.4 1 1 1 2 2 2 0 Latarcin precursor YlqD PF11068.8 ORY39356.1 - 0.62 10.5 10.5 0.67 10.3 4.8 2.0 1 1 1 2 2 2 0 YlqD protein FAM184 PF15665.5 ORY39356.1 - 0.62 9.8 15.1 3 7.6 9.9 2.1 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Prominin PF05478.11 ORY39356.1 - 0.65 7.9 11.9 0.73 7.7 11.9 1.1 1 0 0 1 1 1 0 Prominin T3SS_needle_E PF08988.10 ORY39356.1 - 0.67 10.1 6.6 0.88 9.8 1.3 3.0 1 1 1 3 3 3 0 Type III secretion system, cytoplasmic E component of needle DUF724 PF05266.14 ORY39356.1 - 0.68 9.7 13.0 1.1 9.1 13.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Laminin_II PF06009.12 ORY39356.1 - 0.69 9.9 12.6 0.49 10.4 6.6 2.1 1 1 1 2 2 2 0 Laminin Domain II Muted PF14942.6 ORY39356.1 - 0.72 10.2 12.3 1.6 9.1 11.7 1.8 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein HAUS6_N PF14661.6 ORY39356.1 - 0.75 9.3 8.3 1.1 8.9 8.3 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus APG6_N PF17675.1 ORY39356.1 - 0.75 10.3 17.2 0.78 10.3 5.8 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Occludin_ELL PF07303.13 ORY39356.1 - 0.76 10.5 7.8 4.9 7.9 3.4 2.1 1 1 1 2 2 2 0 Occludin homology domain DUF3958 PF13125.6 ORY39356.1 - 0.78 10.0 11.5 0.63 10.3 1.6 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF3958) KxDL PF10241.9 ORY39356.1 - 0.81 10.0 15.3 0.3 11.4 3.5 3.0 1 1 2 3 3 3 0 Uncharacterized conserved protein BRE1 PF08647.11 ORY39356.1 - 0.98 9.5 16.3 0.86 9.7 1.1 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.10 ORY39356.1 - 1.1 9.5 11.8 8.6 6.5 11.6 2.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family UPF0242 PF06785.11 ORY39356.1 - 1.1 9.3 17.0 11 6.0 17.0 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PilO PF04350.13 ORY39356.1 - 1.1 9.4 9.4 6.6 6.9 0.5 2.6 1 1 1 2 2 2 0 Pilus assembly protein, PilO HALZ PF02183.18 ORY39356.1 - 1.2 9.4 12.1 0.21 11.8 0.7 3.7 3 1 1 4 4 4 0 Homeobox associated leucine zipper Nup54 PF13874.6 ORY39356.1 - 1.4 9.0 9.8 5.1 7.2 9.7 2.0 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 DUF641 PF04859.12 ORY39356.1 - 1.5 9.2 10.3 8.4 6.7 10.3 2.0 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) V_ATPase_I PF01496.19 ORY39356.1 - 1.6 6.6 7.7 2.1 6.1 7.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BST2 PF16716.5 ORY39356.1 - 1.7 9.3 16.5 21 5.8 9.2 2.8 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 TBCA PF02970.16 ORY39356.1 - 1.7 9.0 11.7 0.44 10.9 6.1 2.2 1 1 1 2 2 2 0 Tubulin binding cofactor A HR1 PF02185.16 ORY39356.1 - 1.9 8.7 15.4 46 4.2 10.6 3.6 1 1 1 2 2 2 0 Hr1 repeat Bcr-Abl_Oligo PF09036.10 ORY39356.1 - 1.9 8.6 6.5 3.7 7.6 0.2 3.2 1 1 2 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain DUF4140 PF13600.6 ORY39356.1 - 2.3 8.7 14.9 2.2e+03 -0.8 14.9 3.0 1 1 0 1 1 0 0 N-terminal domain of unknown function (DUF4140) CHDCT2 PF08074.11 ORY39356.1 - 2.3 8.4 8.6 0.55 10.4 0.8 2.1 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain TSC22 PF01166.18 ORY39356.1 - 2.6 8.4 9.5 0.94 9.8 0.8 3.1 1 1 2 3 3 3 0 TSC-22/dip/bun family DASH_Dam1 PF08653.10 ORY39356.1 - 2.6 7.9 7.2 6.4 6.7 0.3 3.2 3 0 0 3 3 3 0 DASH complex subunit Dam1 PRKG1_interact PF15898.5 ORY39356.1 - 2.7 8.9 15.0 21 6.1 13.7 2.6 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF5339 PF17274.2 ORY39356.1 - 3.1 8.7 7.8 7.4 7.5 1.5 3.0 1 1 1 2 2 2 0 Family of unknown function (DUF5339) Spc24 PF08286.11 ORY39356.1 - 3.4 7.9 17.1 22 5.4 0.7 3.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 GrpE PF01025.19 ORY39356.1 - 3.7 7.2 14.3 25 4.5 0.4 2.9 1 1 1 2 2 2 0 GrpE MCC-bdg_PDZ PF10506.9 ORY39356.1 - 4.1 7.5 9.5 3.7 7.6 5.9 2.5 2 1 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome ZapB PF06005.12 ORY39356.1 - 4.4 7.8 15.2 69 4.0 9.6 3.0 1 1 1 2 2 2 0 Cell division protein ZapB DUF5595 PF18077.1 ORY39356.1 - 4.7 7.4 11.0 1.2 9.3 0.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5595) DUF2203 PF09969.9 ORY39356.1 - 5.1 7.8 7.5 50 4.6 7.5 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Lectin_N PF03954.14 ORY39356.1 - 5.1 6.8 10.4 7 6.4 2.1 2.3 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain DUF4337 PF14235.6 ORY39356.1 - 7.8 6.6 8.6 13 5.8 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) zf-C4H2 PF10146.9 ORY39356.1 - 9.2 6.5 11.1 30 4.8 5.4 2.6 1 1 1 2 2 2 0 Zinc finger-containing protein NUC173 PF08161.12 ORY39357.1 - 7e-30 104.2 0.3 5.9e-27 94.7 0.0 3.4 3 1 0 3 3 3 2 NUC173 domain DNA_pol_phi PF04931.13 ORY39357.1 - 0.37 8.9 10.4 0.42 8.6 8.1 2.2 3 0 0 3 3 3 0 DNA polymerase phi Ribosomal_S9 PF00380.19 ORY39359.1 - 8e-39 132.9 0.4 1.2e-38 132.3 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 AAA PF00004.29 ORY39360.1 - 1.2e-43 148.7 0.1 4.4e-13 49.8 0.0 5.1 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.6 ORY39360.1 - 1.4e-21 77.0 0.0 3.2e-20 72.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORY39360.1 - 3.6e-18 66.3 9.9 6.2e-07 29.5 0.0 6.8 7 0 0 7 7 7 2 AAA domain AAA_lid_6 PF17866.1 ORY39360.1 - 3.2e-14 52.8 0.1 0.00011 22.3 0.0 3.8 3 0 0 3 3 3 3 AAA lid domain AAA_30 PF13604.6 ORY39360.1 - 3.3e-12 46.5 0.0 0.17 11.6 0.0 5.6 5 0 0 5 5 5 3 AAA domain AAA_5 PF07728.14 ORY39360.1 - 9.5e-12 45.1 0.8 0.02 14.9 0.0 4.7 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ORY39360.1 - 3.8e-10 39.5 2.4 0.28 10.5 0.0 7.0 5 2 2 7 7 7 3 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 ORY39360.1 - 8.4e-10 39.2 0.4 0.32 11.3 0.1 6.0 5 1 1 6 6 6 2 AAA domain RuvB_N PF05496.12 ORY39360.1 - 5e-09 36.1 0.3 0.16 11.7 0.0 4.6 4 0 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY39360.1 - 6.7e-09 36.4 0.7 0.024 15.0 0.0 5.4 5 1 0 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 ORY39360.1 - 1.6e-08 34.9 13.1 0.28 11.5 0.1 7.6 6 2 0 6 6 5 2 AAA domain RNA_helicase PF00910.22 ORY39360.1 - 7.3e-08 32.8 0.4 0.93 9.9 0.0 5.0 4 0 0 4 4 4 1 RNA helicase Torsin PF06309.11 ORY39360.1 - 1.6e-07 31.5 0.1 0.027 14.6 0.0 3.7 3 0 0 3 3 3 2 Torsin Sigma54_activat PF00158.26 ORY39360.1 - 2.5e-07 30.6 2.9 0.34 10.6 0.5 5.1 3 2 0 3 3 3 2 Sigma-54 interaction domain AAA_2 PF07724.14 ORY39360.1 - 2.5e-07 30.9 0.0 0.58 10.2 0.0 3.5 3 0 0 3 3 3 3 AAA domain (Cdc48 subfamily) Viral_helicase1 PF01443.18 ORY39360.1 - 3e-07 30.4 0.3 0.86 9.3 0.0 4.6 5 0 0 5 5 4 2 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 ORY39360.1 - 4.4e-07 30.5 7.7 1.5 9.4 0.2 5.6 5 0 0 5 5 5 2 AAA domain AAA_33 PF13671.6 ORY39360.1 - 5.7e-07 29.8 2.5 0.25 11.5 0.1 4.7 4 0 0 4 4 4 1 AAA domain zf-RanBP PF00641.18 ORY39360.1 - 6.1e-07 28.6 1.1 1.4e-06 27.5 1.1 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others IstB_IS21 PF01695.17 ORY39360.1 - 6.3e-07 29.3 0.4 1.9 8.2 0.0 5.0 4 1 1 5 5 5 1 IstB-like ATP binding protein NTPase_1 PF03266.15 ORY39360.1 - 3.8e-06 26.9 0.7 1.5 8.7 0.1 3.9 3 0 0 3 3 3 1 NTPase Sigma54_activ_2 PF14532.6 ORY39360.1 - 2e-05 24.7 0.0 0.88 9.7 0.0 4.0 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_24 PF13479.6 ORY39360.1 - 2.1e-05 24.3 1.4 1.2 8.8 0.0 4.5 4 0 0 4 4 4 1 AAA domain AAA_7 PF12775.7 ORY39360.1 - 0.00022 20.8 1.4 7.7 6.0 0.0 4.3 5 0 0 5 5 4 0 P-loop containing dynein motor region TsaE PF02367.17 ORY39360.1 - 0.00067 19.7 0.3 1.6 8.7 0.0 3.8 4 0 0 4 4 4 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 ORY39360.1 - 0.00076 19.0 1.2 3.7 6.9 0.2 3.9 4 0 0 4 4 4 1 PhoH-like protein APS_kinase PF01583.20 ORY39360.1 - 0.0014 18.5 0.4 0.77 9.6 0.0 3.5 4 0 0 4 4 3 1 Adenylylsulphate kinase AAA_3 PF07726.11 ORY39360.1 - 0.0039 17.0 0.0 17 5.3 0.0 3.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.10 ORY39360.1 - 0.011 15.3 0.2 4.1 6.8 0.0 3.2 3 0 0 3 3 3 0 Chromatin associated protein KTI12 NACHT PF05729.12 ORY39360.1 - 0.014 15.3 1.6 9.2 6.2 0.0 4.6 4 1 0 4 4 4 0 NACHT domain ATPase PF06745.13 ORY39360.1 - 0.083 12.2 2.4 17 4.7 0.0 3.7 4 0 0 4 4 3 0 KaiC DUF2075 PF09848.9 ORY39360.1 - 0.088 12.0 6.9 23 4.1 0.1 4.8 5 1 0 5 5 4 0 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.13 ORY39360.1 - 0.098 11.8 0.3 5.8 6.0 0.0 3.9 4 1 1 5 5 5 0 TIP49 P-loop domain CbiA PF01656.23 ORY39360.1 - 0.18 11.9 0.6 30 4.7 0.0 3.2 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PRK PF00485.18 ORY39360.1 - 0.18 11.5 0.6 21 4.8 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Parvo_NS1 PF01057.17 ORY39360.1 - 0.19 10.8 0.2 10 5.1 0.0 2.7 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 ORY39360.1 - 0.23 11.7 0.0 0.23 11.7 0.0 4.3 5 0 0 5 5 3 0 AAA domain DUF3987 PF13148.6 ORY39360.1 - 0.25 10.3 8.1 3.4 6.6 0.0 4.1 4 0 0 4 4 3 0 Protein of unknown function (DUF3987) ABC_tran PF00005.27 ORY39360.1 - 0.47 11.0 10.3 25 5.3 0.0 5.1 5 1 0 5 5 4 0 ABC transporter AAA_13 PF13166.6 ORY39360.1 - 0.77 8.3 9.4 0.59 8.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 ORY39360.1 - 3.7 8.0 18.6 12 6.3 7.6 4.3 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.6 ORY39360.1 - 4.6 6.8 10.1 32 4.0 0.0 4.7 5 0 0 5 5 5 0 AAA domain SEP PF08059.13 ORY39361.1 - 3.3e-21 75.6 0.3 5.1e-20 71.8 0.0 2.6 2 1 1 3 3 3 1 SEP domain UBX PF00789.20 ORY39361.1 - 3.6e-17 62.3 0.0 5.9e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 UBX domain Acetyltransf_2 PF00797.17 ORY39362.1 - 4.7e-70 236.1 0.0 3.7e-35 121.9 0.0 2.0 2 0 0 2 2 2 2 N-acetyltransferase Transglut_core PF01841.19 ORY39362.1 - 0.0013 19.2 0.0 0.13 12.7 0.0 2.4 2 0 0 2 2 2 1 Transglutaminase-like superfamily Tox-PLDMTX PF15645.6 ORY39362.1 - 0.11 12.8 0.0 3.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Dermonecrotoxin of the Papain-like fold Defensin_2 PF01097.18 ORY39362.1 - 0.19 11.7 0.3 12 5.9 0.1 2.4 2 0 0 2 2 2 0 Arthropod defensin ABA_GPCR PF12430.8 ORY39364.1 - 7.4e-39 133.4 8.4 7.4e-39 133.4 8.4 2.3 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 ORY39364.1 - 2.8e-19 69.0 0.0 6.1e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal LMBR1 PF04791.16 ORY39364.1 - 0.58 9.0 10.3 1.9 7.3 9.9 2.0 1 1 0 1 1 1 0 LMBR1-like membrane protein Carn_acyltransf PF00755.20 ORY39365.1 - 2.5e-202 673.6 0.0 2.9e-202 673.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Carn_acyltransf PF00755.20 ORY39366.1 - 1.9e-207 690.6 0.0 2.1e-207 690.4 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Ribosomal_S2 PF00318.20 ORY39367.1 - 3.6e-49 166.9 0.2 1.6e-48 164.8 0.2 1.8 1 1 0 1 1 1 1 Ribosomal protein S2 NIBRIN_BRCT_II PF16508.5 ORY39368.1 - 3.2e-06 27.5 0.1 1.2e-05 25.6 0.0 1.9 2 0 0 2 2 2 1 Second BRCT domain on Nijmegen syndrome breakage protein DUF5102 PF17104.5 ORY39368.1 - 0.0014 18.8 2.9 0.0024 18.0 2.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5102) Mt_ATP-synt_B PF05405.14 ORY39368.1 - 0.14 11.7 0.5 0.25 11.0 0.5 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Mid2 PF04478.12 ORY39369.1 - 0.07 13.0 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor MORN PF02493.20 ORY39372.1 - 3.8e-29 98.8 40.4 4.4e-07 29.4 0.9 7.3 8 0 0 8 8 8 6 MORN repeat DUF3048_C PF17479.2 ORY39372.1 - 0.25 11.8 5.7 1.7 9.1 5.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3048) C-terminal domain LRR_4 PF12799.7 ORY39373.1 - 4.4e-07 30.1 7.9 0.004 17.5 1.5 4.1 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORY39373.1 - 1.9e-06 27.5 5.3 0.0002 20.9 0.7 3.8 2 1 1 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 ORY39373.1 - 2.6e-06 27.1 7.5 0.011 15.4 3.4 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 ORY39373.1 - 0.0026 17.7 3.0 0.78 9.9 0.5 3.8 3 0 0 3 3 3 1 Leucine Rich repeat Filament PF00038.21 ORY39373.1 - 0.0048 16.5 47.7 0.0048 16.5 47.7 3.4 3 1 1 4 4 4 1 Intermediate filament protein DUF1664 PF07889.12 ORY39373.1 - 0.96 9.5 46.1 0.28 11.2 2.1 5.8 5 1 1 6 6 6 0 Protein of unknown function (DUF1664) GP57 PF17594.2 ORY39373.1 - 5.9 6.7 9.6 1.6 8.5 0.0 4.0 3 1 1 4 4 4 0 Phage Tail fiber assembly helper gene product 57 SAM_Exu PF18609.1 ORY39373.1 - 8.4 6.6 13.3 3.3 7.9 0.8 3.9 3 1 0 3 3 3 0 Exuperantia SAM-like domain Mob1_phocein PF03637.17 ORY39374.1 - 4.8e-50 169.9 0.7 5.5e-50 169.7 0.7 1.0 1 0 0 1 1 1 1 Mob1/phocein family DUF1965 PF09248.10 ORY39374.1 - 0.041 13.6 0.1 0.07 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1965) TBCA PF02970.16 ORY39375.1 - 3e-28 98.0 5.0 3.7e-28 97.7 5.0 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Spc7 PF08317.11 ORY39375.1 - 0.045 12.6 5.6 0.05 12.5 5.6 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein ChaC PF04752.12 ORY39375.1 - 0.13 12.3 0.1 0.15 12.1 0.1 1.0 1 0 0 1 1 1 0 ChaC-like protein DUF569 PF04601.13 ORY39375.1 - 0.14 11.8 0.9 0.3 10.8 0.5 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF569) TMF_DNA_bd PF12329.8 ORY39375.1 - 0.2 11.7 5.5 0.11 12.5 2.5 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding XRN_M PF17846.1 ORY39375.1 - 0.23 10.4 1.7 0.25 10.3 1.7 1.0 1 0 0 1 1 1 0 Xrn1 helical domain Pkinase PF00069.25 ORY39376.1 - 2.5e-73 246.7 0.8 2.6e-73 246.6 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY39376.1 - 9.4e-35 120.1 0.3 1.6e-34 119.4 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY39376.1 - 0.0035 16.4 4.9 0.0043 16.0 0.0 2.6 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 ORY39376.1 - 0.15 12.0 7.0 0.16 11.9 0.0 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family TFIIA PF03153.13 ORY39376.1 - 0.75 9.7 27.4 1.1 9.2 27.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GYF PF02213.16 ORY39377.1 - 1.6e-17 62.9 1.1 3.4e-17 61.8 1.1 1.5 1 0 0 1 1 1 1 GYF domain TAF4 PF05236.14 ORY39377.1 - 0.001 18.9 0.2 0.0025 17.6 0.2 1.7 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family GYF_2 PF14237.6 ORY39377.1 - 0.016 15.0 0.0 0.04 13.7 0.0 1.7 1 0 0 1 1 1 0 GYF domain 2 Lon_C PF05362.13 ORY39378.1 - 1.3e-76 256.7 0.5 2.4e-76 255.8 0.5 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 ORY39378.1 - 3.5e-21 76.0 0.1 6.8e-21 75.1 0.1 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 ORY39378.1 - 6.5e-21 75.1 0.0 2.2e-20 73.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY39378.1 - 2.3e-08 34.1 0.0 5.5e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 ORY39378.1 - 1.2e-07 31.6 0.0 4.9e-07 29.6 0.0 2.2 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 ORY39378.1 - 0.00013 22.1 0.0 0.00036 20.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 ORY39378.1 - 0.00023 21.0 0.0 0.0082 15.9 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_PrkA PF08298.11 ORY39378.1 - 0.00057 18.9 0.0 0.0011 17.9 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_3 PF07726.11 ORY39378.1 - 0.00078 19.3 0.0 0.0024 17.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 ORY39378.1 - 0.002 18.0 0.0 0.0057 16.6 0.0 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 ORY39378.1 - 0.0029 17.9 1.1 0.098 12.9 0.1 3.0 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY39378.1 - 0.016 15.6 3.9 0.017 15.5 0.1 2.7 2 2 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 ORY39378.1 - 0.024 15.2 0.1 0.065 13.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ORY39378.1 - 0.027 14.2 0.1 0.067 12.9 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein NACHT PF05729.12 ORY39378.1 - 0.089 12.7 1.1 0.91 9.4 0.0 2.9 3 0 0 3 3 3 0 NACHT domain RNA_helicase PF00910.22 ORY39378.1 - 0.089 13.2 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 ORY39378.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 ORY39378.1 - 0.13 12.6 0.9 2 8.9 0.0 3.0 2 1 0 2 2 2 0 AAA domain LTXXQ PF07813.12 ORY39378.1 - 0.16 12.7 2.3 4.4 8.1 0.6 3.2 3 0 0 3 3 3 0 LTXXQ motif family protein AAA_23 PF13476.6 ORY39378.1 - 0.25 11.8 0.0 0.25 11.8 0.0 2.7 2 1 0 2 2 1 0 AAA domain E1_dh PF00676.20 ORY39379.1 - 2.2e-86 289.5 0.2 6.2e-86 288.0 0.2 1.6 1 1 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.21 ORY39379.1 - 9e-05 21.6 0.0 0.00017 20.7 0.0 1.5 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain TPP_enzyme_C PF02775.21 ORY39379.1 - 9.3e-05 22.3 2.5 0.00017 21.4 0.2 2.2 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 ORY39379.1 - 0.00046 19.5 0.0 0.0014 17.9 0.0 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Aminotran_1_2 PF00155.21 ORY39380.1 - 3.6e-21 75.8 0.0 1.2e-11 44.5 0.0 2.6 2 1 1 3 3 3 2 Aminotransferase class I and II E1_dh PF00676.20 ORY39381.1 - 4.9e-101 337.6 0.2 6.2e-101 337.3 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 ORY39381.1 - 3e-05 23.8 0.2 0.00032 20.5 0.2 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 ORY39381.1 - 0.00014 21.2 0.0 0.0016 17.7 0.0 2.2 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Amidase02_C PF12123.8 ORY39381.1 - 0.065 12.9 3.4 0.11 12.2 1.7 2.1 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase Suf PF05843.14 ORY39382.1 - 6.4e-65 220.1 9.0 1.2e-56 192.9 0.3 4.6 4 2 0 5 5 5 3 Suppressor of forked protein (Suf) TPR_14 PF13428.6 ORY39382.1 - 1.9e-08 34.5 17.8 0.00053 20.6 4.5 5.7 4 1 2 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY39382.1 - 1.7e-06 28.6 13.7 0.0016 19.0 3.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY39382.1 - 2.3e-06 27.3 0.2 0.0087 16.1 0.3 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY39382.1 - 0.00011 22.6 9.9 0.042 14.4 0.9 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat NRDE-2 PF08424.10 ORY39382.1 - 0.0036 16.5 2.9 0.034 13.3 0.4 3.2 2 1 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_8 PF13181.6 ORY39382.1 - 0.015 15.5 4.4 1.1 9.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY39382.1 - 0.016 15.8 4.4 12 6.8 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY39382.1 - 0.019 14.9 2.2 1.2 9.1 0.8 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY39382.1 - 0.12 12.7 1.6 0.98 9.8 0.5 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3915 PF13054.6 ORY39382.1 - 0.18 11.8 2.8 0.36 10.8 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) FTCD_C PF04961.12 ORY39382.1 - 0.35 10.6 2.3 1.7 8.4 0.0 2.9 3 1 1 4 4 4 0 Formiminotransferase-cyclodeaminase Atrophin-1 PF03154.15 ORY39382.1 - 0.54 8.5 4.2 0.82 7.9 4.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family TPR_4 PF07721.14 ORY39382.1 - 8.2 7.4 6.7 0.99 10.2 1.1 2.7 2 0 0 2 2 1 0 Tetratricopeptide repeat TSNAXIP1_N PF15739.5 ORY39383.1 - 3.7e-17 62.7 5.0 3.7e-17 62.7 5.0 3.5 2 1 0 3 3 3 1 Translin-associated factor X-interacting N-terminus Csm1_N PF18504.1 ORY39383.1 - 1.6e-05 25.2 24.2 0.084 13.2 3.1 5.1 3 1 0 4 4 4 3 Csm1 N-terminal domain Microtub_bd PF16796.5 ORY39383.1 - 0.0013 18.7 0.1 0.0044 17.0 0.1 1.9 1 0 0 1 1 1 1 Microtubule binding DUF4795 PF16043.5 ORY39383.1 - 0.0066 16.1 22.2 0.0066 16.1 11.5 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4795) Phage_GP20 PF06810.11 ORY39383.1 - 0.011 15.6 16.0 0.4 10.5 5.1 2.7 1 1 1 2 2 2 0 Phage minor structural protein GP20 TolA_bind_tri PF16331.5 ORY39383.1 - 0.022 14.8 14.8 0.036 14.1 0.6 4.4 4 2 0 4 4 4 0 TolA binding protein trimerisation Spc7 PF08317.11 ORY39383.1 - 0.25 10.2 26.2 0.65 8.8 4.2 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein FlxA PF14282.6 ORY39383.1 - 0.29 11.1 18.7 7.4 6.6 7.3 3.5 1 1 1 2 2 2 0 FlxA-like protein bZIP_1 PF00170.21 ORY39383.1 - 0.32 11.1 22.2 0.064 13.4 4.2 4.3 4 0 0 4 4 4 0 bZIP transcription factor Golgin_A5 PF09787.9 ORY39383.1 - 0.43 10.0 25.7 1.9 7.9 25.6 1.8 1 1 0 1 1 1 0 Golgin subfamily A member 5 Tropomyosin_1 PF12718.7 ORY39383.1 - 0.5 10.5 26.8 2.5 8.3 11.6 2.8 2 1 1 3 3 2 0 Tropomyosin like XhlA PF10779.9 ORY39383.1 - 0.75 10.1 5.4 2.6 8.3 0.5 2.8 2 0 0 2 2 2 0 Haemolysin XhlA DivIC PF04977.15 ORY39383.1 - 0.78 9.5 18.3 1.8 8.4 1.6 4.2 3 2 0 3 3 3 0 Septum formation initiator CHDCT2 PF08074.11 ORY39383.1 - 1 9.5 9.5 0.38 10.9 5.2 2.3 2 1 1 3 3 3 0 CHDCT2 (NUC038) domain DUF4407 PF14362.6 ORY39383.1 - 1 8.7 17.6 3.3 7.0 10.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Swi5 PF07061.11 ORY39383.1 - 1.4 9.1 16.8 0.77 9.9 1.7 3.8 2 1 1 3 3 3 0 Swi5 LMBR1 PF04791.16 ORY39383.1 - 1.4 7.8 8.9 21 3.9 8.9 2.1 1 1 0 1 1 1 0 LMBR1-like membrane protein Nas2_N PF18265.1 ORY39383.1 - 1.7 8.6 5.1 9.6 6.2 0.5 3.9 3 1 0 3 3 3 0 Nas2 N_terminal domain PKcGMP_CC PF16808.5 ORY39383.1 - 1.8 8.5 8.4 2.9 7.8 0.9 3.8 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ERM PF00769.19 ORY39383.1 - 5.9 6.6 25.6 9.3 6.0 1.6 2.3 1 1 0 2 2 2 0 Ezrin/radixin/moesin family MCC-bdg_PDZ PF10506.9 ORY39383.1 - 6.5 6.9 14.4 10 6.2 0.1 4.3 4 0 0 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF5320 PF17253.2 ORY39383.1 - 6.6 7.9 11.2 2.1 9.4 1.0 3.7 2 1 1 3 3 3 0 Family of unknown function (DUF5320) Cep57_MT_bd PF06657.13 ORY39383.1 - 6.9 7.2 11.0 0.69 10.4 0.3 4.0 3 1 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 CC2-LZ PF16516.5 ORY39383.1 - 9.1 6.7 22.1 2 8.8 0.3 4.6 4 1 0 5 5 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DNA_methylase PF00145.17 ORY39384.1 - 3.1e-27 95.8 0.0 4.6e-20 72.2 0.0 2.1 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase SE PF08491.10 ORY39385.1 - 3.1e-112 374.1 0.0 3.9e-112 373.8 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 ORY39385.1 - 7.1e-16 58.4 0.0 9.5e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY39385.1 - 1.6e-08 34.6 0.1 0.0001 22.0 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY39385.1 - 6.3e-06 26.3 0.2 1.6e-05 25.0 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY39385.1 - 7.1e-05 22.2 0.1 0.00012 21.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY39385.1 - 0.00024 20.3 0.1 0.00035 19.8 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 ORY39385.1 - 0.00031 20.0 0.3 0.00057 19.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 ORY39385.1 - 0.0013 18.0 0.0 0.0034 16.6 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 ORY39385.1 - 0.003 17.0 0.2 0.0043 16.5 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ORY39385.1 - 0.0035 16.4 0.3 0.0088 15.1 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 ORY39385.1 - 0.0057 15.4 0.0 0.0086 14.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 ORY39385.1 - 0.011 14.7 2.0 1.7 7.4 0.0 2.3 1 1 1 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 ORY39385.1 - 0.075 12.3 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 ORY39385.1 - 0.13 10.8 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor ApbA PF02558.16 ORY39385.1 - 0.14 11.8 0.2 0.36 10.5 0.1 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA cNMP_binding PF00027.29 ORY39386.1 - 2.4e-18 66.0 0.0 5.2e-18 64.9 0.0 1.6 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 ORY39386.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Cupin domain PIG-P PF08510.12 ORY39388.1 - 1.3e-26 92.9 5.3 1.5e-26 92.7 5.3 1.0 1 0 0 1 1 1 1 PIG-P Phage_holin_3_6 PF07332.11 ORY39388.1 - 0.058 13.4 2.0 0.075 13.1 2.0 1.1 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DPM2 PF07297.12 ORY39388.1 - 0.074 13.4 10.0 0.12 12.7 10.0 1.3 1 1 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Bromodomain PF00439.25 ORY39389.1 - 8.3e-18 64.2 0.3 2.3e-17 62.8 0.3 1.7 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 ORY39389.1 - 6.3e-07 29.3 0.1 2.3e-06 27.5 0.1 1.9 1 0 0 1 1 1 1 Bromodomain associated HEPN_Swt1 PF18731.1 ORY39389.1 - 0.071 13.5 0.3 0.071 13.5 0.3 3.7 4 1 1 5 5 5 0 Swt1-like HEPN DUF2992 PF11208.8 ORY39389.1 - 4.8 7.4 18.2 1.8 8.8 14.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Yae1_N PF09811.9 ORY39390.1 - 1.3e-11 44.0 5.4 1.9e-10 40.2 5.4 2.1 1 1 0 1 1 1 1 Essential protein Yae1, N terminal CATSPERD PF15020.6 ORY39391.1 - 6.1e-09 34.7 1.5 7.5e-09 34.5 1.5 1.0 1 0 0 1 1 1 1 Cation channel sperm-associated protein subunit delta BNR PF02012.20 ORY39391.1 - 0.014 15.3 0.4 0.11 12.5 0.3 2.6 2 0 0 2 2 2 0 BNR/Asp-box repeat CATSPERD PF15020.6 ORY39392.1 - 1.2e-16 60.2 0.1 1.4e-16 60.0 0.1 1.0 1 0 0 1 1 1 1 Cation channel sperm-associated protein subunit delta DUF485 PF04341.12 ORY39392.1 - 0.013 15.5 1.2 0.023 14.7 1.1 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF485 CATSPERB PF15149.6 ORY39392.1 - 0.027 13.0 0.2 0.034 12.7 0.2 1.0 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit beta protein family MAS20 PF02064.15 ORY39393.1 - 1.9e-35 121.7 1.2 2.5e-35 121.4 1.2 1.1 1 0 0 1 1 1 1 MAS20 protein import receptor GRASP55_65 PF04495.14 ORY39394.1 - 1.2e-13 51.5 0.0 1.7e-05 25.2 0.0 2.0 2 0 0 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 ORY39394.1 - 0.16 12.3 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 PDZ domain GRASP55_65 PF04495.14 ORY39395.1 - 2.3e-19 70.0 0.0 2.6e-19 69.9 0.0 1.0 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain Pkinase PF00069.25 ORY39397.1 - 6.2e-74 248.7 0.0 8.7e-74 248.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY39397.1 - 1.1e-37 129.7 0.0 1.7e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 ORY39397.1 - 4e-17 62.8 0.2 2e-09 37.9 0.0 2.5 1 1 1 2 2 2 2 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 ORY39397.1 - 1.6e-07 30.9 0.0 2.1e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY39397.1 - 0.00054 19.0 0.5 0.0013 17.8 0.5 1.6 1 0 0 1 1 1 1 Haspin like kinase domain UBA_2 PF08587.11 ORY39397.1 - 0.0027 17.8 0.0 0.015 15.4 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) APH PF01636.23 ORY39397.1 - 0.17 11.8 0.1 0.77 9.6 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 ORY39397.1 - 0.49 9.7 1.9 1.7 8.0 1.9 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CoA_binding PF02629.19 ORY39398.1 - 8.7e-32 109.7 0.9 8.7e-32 109.7 0.9 2.2 3 0 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.19 ORY39398.1 - 3.5e-19 69.1 0.0 6.3e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 CoA-ligase CoA_binding_2 PF13380.6 ORY39398.1 - 9.1e-05 22.9 0.1 0.00025 21.5 0.1 1.7 1 0 0 1 1 1 1 CoA binding domain DHC_N1 PF08385.12 ORY39399.1 - 5.2e-157 523.9 4.7 7.8e-108 361.5 0.2 3.9 2 1 1 3 3 3 2 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 ORY39399.1 - 1.1e-130 435.4 0.3 2e-128 428.0 0.0 2.7 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 ORY39399.1 - 1.2e-92 310.4 0.3 6.5e-92 308.0 0.1 2.5 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain DHC_N2 PF08393.13 ORY39399.1 - 1.4e-89 301.0 24.3 7.2e-77 259.1 3.5 5.2 3 1 1 4 4 4 2 Dynein heavy chain, N-terminal region 2 MT PF12777.7 ORY39399.1 - 1.2e-84 284.3 19.3 7.9e-49 166.5 12.4 4.1 2 1 1 3 3 3 2 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 ORY39399.1 - 2.2e-74 249.3 0.2 2.2e-74 249.3 0.2 2.6 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_8 PF12780.7 ORY39399.1 - 4.8e-70 235.9 6.5 1.2e-68 231.3 2.2 3.9 3 1 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 ORY39399.1 - 1.6e-69 233.0 0.0 3.5e-66 222.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 ORY39399.1 - 9e-48 162.2 0.0 2.4e-47 160.8 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 ORY39399.1 - 7.3e-22 77.7 1.5 3.9e-21 75.3 0.0 3.2 2 1 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 ORY39399.1 - 1.2e-18 67.1 1.7 6e-17 61.7 1.7 3.1 1 1 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 ORY39399.1 - 1.5e-14 54.2 0.0 2.2e-06 27.7 0.0 4.8 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 ORY39399.1 - 9.7e-08 32.2 0.0 9.7e-07 28.9 0.0 2.9 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 ORY39399.1 - 0.00019 21.9 0.0 0.055 13.9 0.0 4.0 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 ORY39399.1 - 0.00051 20.5 0.0 0.34 11.3 0.0 3.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY39399.1 - 0.0019 18.5 0.1 1.8 8.9 0.0 3.7 2 1 1 3 3 3 1 AAA domain AAA_25 PF13481.6 ORY39399.1 - 0.036 13.6 0.1 0.14 11.7 0.0 2.1 2 0 0 2 2 1 0 AAA domain Rad17 PF03215.15 ORY39399.1 - 0.044 13.7 0.0 9.4 6.1 0.0 3.4 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_14 PF13173.6 ORY39399.1 - 0.052 13.6 0.1 3.1 7.8 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 ORY39399.1 - 0.074 13.4 0.6 22 5.4 0.0 3.8 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 ORY39399.1 - 0.11 12.4 0.4 0.53 10.2 0.0 2.5 2 0 0 2 2 2 0 NACHT domain NRN1 PF15056.6 ORY39399.1 - 1 9.5 3.6 5.9 7.0 0.0 3.8 3 0 0 3 3 3 0 Neuritin protein family AAA_18 PF13238.6 ORY39399.1 - 2.3 8.8 6.2 2.6 8.6 0.0 4.0 3 0 0 3 3 3 0 AAA domain OpuAC PF04069.12 ORY39401.1 - 1.6e-14 54.1 0.2 2.9e-11 43.5 0.1 2.2 2 0 0 2 2 2 2 Substrate binding domain of ABC-type glycine betaine transport system DNA_pol_B_palm PF14792.6 ORY39402.1 - 5.5e-25 87.8 0.0 1.2e-24 86.7 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 ORY39402.1 - 6.1e-21 74.4 0.0 1.5e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 ORY39402.1 - 3.9e-18 65.0 0.2 7.1e-18 64.2 0.2 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 ORY39402.1 - 4.1e-17 62.3 0.3 8.1e-15 54.9 0.1 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain BRCT PF00533.26 ORY39402.1 - 1e-05 25.8 0.9 2.4e-05 24.6 0.1 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 ORY39402.1 - 0.00032 21.1 0.0 0.00071 19.9 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Cdd1 PF11731.8 ORY39402.1 - 0.00062 19.9 0.0 0.0017 18.6 0.0 1.7 1 0 0 1 1 1 1 Pathogenicity locus HHH_5 PF14520.6 ORY39402.1 - 0.0022 18.5 0.1 0.16 12.6 0.0 2.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain LIG3_BRCT PF16759.5 ORY39402.1 - 0.0043 17.3 0.0 0.0088 16.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain IMS_HHH PF11798.8 ORY39402.1 - 0.078 13.3 0.2 0.61 10.5 0.0 2.6 2 0 0 2 2 2 0 IMS family HHH motif DUF1564 PF07600.11 ORY39402.1 - 0.081 12.6 1.4 0.12 12.1 0.7 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1564) tRNA-synt_2d PF01409.20 ORY39403.1 - 1.8e-53 181.5 0.7 2.9e-29 102.3 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 ORY39403.1 - 1.2e-24 86.5 0.0 2.7e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain GrpE PF01025.19 ORY39404.1 - 1.4e-46 158.2 0.3 1.5e-46 158.1 0.3 1.0 1 0 0 1 1 1 1 GrpE PRP38 PF03371.15 ORY39404.1 - 0.013 15.4 0.1 0.017 15.0 0.1 1.2 1 0 0 1 1 1 0 PRP38 family Apt1 PF10351.9 ORY39404.1 - 0.039 12.8 0.3 0.042 12.7 0.3 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Mit_KHE1 PF10173.9 ORY39404.1 - 0.054 13.6 0.0 0.059 13.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Glyco_transf_88 PF16849.5 ORY39404.1 - 0.089 11.7 0.0 0.092 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 88 Clusterin PF01093.17 ORY39404.1 - 0.12 11.4 0.1 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Clusterin NDUFB10 PF10249.9 ORY39405.1 - 0.00027 21.4 0.1 0.00032 21.2 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 60KD_IMP PF02096.20 ORY39405.1 - 0.085 12.8 0.1 0.1 12.5 0.1 1.1 1 0 0 1 1 1 0 60Kd inner membrane protein zf-CCHH PF10283.9 ORY39405.1 - 0.092 12.7 0.3 0.14 12.2 0.3 1.3 1 0 0 1 1 1 0 PBZ domain RNA_pol_Rpb5_C PF01191.19 ORY39406.1 - 2.1e-34 117.2 0.1 4.1e-34 116.3 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 ORY39406.1 - 1.5e-25 89.6 0.0 2.6e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 ORY39406.1 - 0.088 12.8 0.0 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 Restriction endonuclease Sld3_N PF18523.1 ORY39406.1 - 0.11 12.6 0.2 0.19 11.8 0.2 1.4 1 0 0 1 1 1 0 Sld3 N-terminal domain IBN_N PF03810.19 ORY39407.1 - 0.0012 18.7 0.1 0.0036 17.2 0.1 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain RNA_pol_Rpb2_6 PF00562.28 ORY39408.1 - 3e-126 421.6 0.7 5.1e-126 420.9 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 ORY39408.1 - 8.3e-62 208.3 0.2 1.2e-61 207.8 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 ORY39408.1 - 2.4e-49 167.5 0.3 5.2e-49 166.5 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 ORY39408.1 - 1.3e-35 121.6 1.2 2.1e-34 117.8 0.2 2.9 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 ORY39408.1 - 5.7e-25 87.3 0.1 1.5e-24 85.9 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 ORY39408.1 - 1.8e-22 79.4 0.0 4.5e-22 78.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 ORY39408.1 - 1.8e-18 66.8 0.1 5e-18 65.4 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 SpoU_methylase PF00588.19 ORY39409.1 - 1.3e-30 106.5 0.0 2.2e-27 96.0 0.0 2.4 2 0 0 2 2 2 2 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 ORY39409.1 - 3.3e-06 27.3 0.0 1.2e-05 25.5 0.0 1.9 1 1 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Peptidase_C14 PF00656.22 ORY39410.1 - 2.6e-43 148.8 0.0 3.5e-43 148.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.22 ORY39411.1 - 2.5e-44 152.1 0.0 3.2e-44 151.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Mucin PF01456.17 ORY39411.1 - 0.0018 18.3 0.7 0.0035 17.4 0.7 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF2228 PF10228.9 ORY39411.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) Sec5 PF15469.6 ORY39412.1 - 9.5e-49 165.8 10.5 3.1e-48 164.1 7.5 3.0 2 1 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.11 ORY39412.1 - 0.0028 17.7 0.1 0.0097 16.0 0.1 2.0 1 0 0 1 1 1 1 Vps51/Vps67 SecA_SW PF07516.13 ORY39412.1 - 5.8 6.9 7.1 9.6 6.2 2.5 3.1 2 1 0 2 2 2 0 SecA Wing and Scaffold domain DUF3399 PF11879.8 ORY39413.1 - 0.01 16.2 0.2 0.018 15.4 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3399) NDUFB11 PF17250.2 ORY39414.1 - 0.11 13.1 0.2 0.16 12.7 0.2 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase 11 kDa subunit Xpo1 PF08389.12 ORY39415.1 - 5.7e-18 65.4 0.0 3.1e-16 59.8 0.0 3.3 4 0 0 4 4 4 1 Exportin 1-like protein Importin_rep PF18773.1 ORY39415.1 - 0.00035 20.2 0.0 0.00095 18.8 0.0 1.8 1 0 0 1 1 1 1 Importin 13 repeat U3snoRNP10 PF12397.8 ORY39415.1 - 0.11 12.8 0.0 0.61 10.5 0.0 2.3 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 UQ_con PF00179.26 ORY39416.1 - 1.5e-36 125.2 0.0 1.7e-36 125.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ABC_tran PF00005.27 ORY39417.1 - 1e-41 142.6 0.0 2.5e-22 79.8 0.0 3.2 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ORY39417.1 - 1.3e-16 61.2 0.0 3.6e-09 36.8 0.0 3.2 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 ORY39417.1 - 6.1e-07 28.9 56.5 1.6e-05 24.2 24.1 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein SbcCD_C PF13558.6 ORY39417.1 - 3e-05 24.1 0.0 0.54 10.5 0.0 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 ORY39417.1 - 0.00017 21.1 0.0 1.4 8.3 0.0 3.0 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY39417.1 - 0.015 15.7 0.1 0.035 14.5 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 ORY39417.1 - 0.21 11.3 0.0 4.9 6.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Acetyltransf_1 PF00583.25 ORY39418.1 - 2.7e-10 40.5 0.0 3.4e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY39418.1 - 1.1e-08 35.1 0.0 1.7e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY39418.1 - 4.9e-07 30.1 0.1 8.4e-07 29.3 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY39418.1 - 0.00011 22.1 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 ORY39418.1 - 0.003 17.6 0.2 0.0049 17.0 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.7 ORY39419.1 - 0.00061 20.5 0.0 0.0012 19.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 ORY39419.1 - 0.012 15.5 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_1 PF00561.20 ORY39419.1 - 0.013 15.1 0.0 0.17 11.5 0.0 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF915 PF06028.11 ORY39419.1 - 0.27 10.5 0.0 0.35 10.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PseudoU_synth_2 PF00849.22 ORY39421.1 - 1.4e-18 67.5 0.0 1.7e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Zn_clus PF00172.18 ORY39422.1 - 0.0045 17.1 12.5 0.0087 16.2 12.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UvrD_C_2 PF13538.6 ORY39423.1 - 2.5e-08 33.6 0.1 0.00076 19.3 0.0 3.1 3 0 0 3 3 3 2 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 ORY39423.1 - 1.2e-07 31.4 0.0 2.6e-06 27.1 0.0 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 ORY39423.1 - 0.0002 21.7 0.0 0.01 16.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORY39423.1 - 0.0019 18.5 0.0 0.22 11.8 0.0 3.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY39423.1 - 0.033 13.9 0.0 0.44 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 ORY39423.1 - 0.055 13.0 0.0 0.25 10.8 0.0 2.0 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Vps39_1 PF10366.9 ORY39423.1 - 0.059 13.7 0.1 13 6.1 0.2 2.9 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 DEAD PF00270.29 ORY39423.1 - 0.16 11.8 0.0 0.88 9.3 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase Peptidase_M76 PF09768.9 ORY39425.1 - 4.4e-60 202.4 2.0 4.9e-60 202.2 2.0 1.0 1 0 0 1 1 1 1 Peptidase M76 family FAD_binding_3 PF01494.19 ORY39426.1 - 4.5e-25 88.7 3.7 6.2e-24 84.9 3.7 2.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY39426.1 - 4.6e-08 32.7 1.4 0.0014 17.9 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY39426.1 - 4.6e-06 25.9 0.9 0.0068 15.5 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein Trp_halogenase PF04820.14 ORY39426.1 - 9.7e-06 24.7 2.5 0.0054 15.6 0.0 2.2 1 1 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.14 ORY39426.1 - 1.3e-05 24.1 2.8 0.049 12.3 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 ORY39426.1 - 8.6e-05 21.8 1.1 0.00013 21.2 1.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY39426.1 - 0.00017 21.3 2.7 0.084 12.4 0.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY39426.1 - 0.00045 20.4 0.7 0.0012 19.1 0.3 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ORY39426.1 - 0.00079 18.6 2.9 0.0014 17.8 2.9 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A SE PF08491.10 ORY39426.1 - 0.0056 15.8 0.0 0.027 13.6 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.27 ORY39426.1 - 0.0087 16.6 0.7 6.4 7.4 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORY39426.1 - 0.015 14.6 2.1 0.024 14.0 1.8 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY39426.1 - 0.017 14.4 0.8 0.91 8.7 0.3 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.28 ORY39427.1 - 3.9e-98 328.8 0.2 4.9e-98 328.5 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme SH3_1 PF00018.28 ORY39427.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 SH3 domain DUF2415 PF10313.9 ORY39428.1 - 1.2e-13 50.8 0.1 1.4e-11 44.2 0.1 2.6 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.32 ORY39428.1 - 1.1e-07 32.3 1.8 0.041 14.8 0.2 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY39428.1 - 5e-05 23.5 0.0 0.095 13.0 0.0 3.2 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 ORY39428.1 - 0.0013 18.6 0.1 2 8.5 0.1 2.5 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Lgl_C PF08596.10 ORY39428.1 - 0.0039 15.9 0.0 0.012 14.3 0.0 1.7 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal Frtz PF11768.8 ORY39428.1 - 0.0042 15.5 0.0 0.0099 14.2 0.0 1.6 1 1 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz Utp8 PF10395.9 ORY39428.1 - 0.051 12.1 0.0 0.074 11.5 0.0 1.3 1 0 0 1 1 1 0 Utp8 family RRM_1 PF00076.22 ORY39429.1 - 9.3e-14 51.0 0.1 1.4e-13 50.4 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORY39429.1 - 0.0012 18.9 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif Nup35_RRM_2 PF14605.6 ORY39429.1 - 0.17 11.9 0.1 0.25 11.4 0.1 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF5531 PF17671.1 ORY39429.1 - 3.6 7.4 4.6 0.4 10.6 0.1 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5531) ANAPC4_WD40 PF12894.7 ORY39430.1 - 4.6e-07 30.0 0.1 1.3 9.4 0.0 5.7 4 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY39430.1 - 1.8e-05 25.4 10.5 2.5 9.1 0.1 8.1 10 0 0 10 10 10 2 WD domain, G-beta repeat eIF2A PF08662.11 ORY39430.1 - 0.00024 21.1 0.0 0.19 11.6 0.0 3.4 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A DUF4326 PF14216.6 ORY39430.1 - 8.3 7.2 6.4 87 3.9 0.2 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4326) DUF1917 PF08939.10 ORY39431.1 - 2.9e-31 109.3 0.0 4.2e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Epimerase PF01370.21 ORY39432.1 - 4.4e-23 82.0 0.0 9.8e-23 80.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY39432.1 - 7.2e-19 68.3 0.2 5.1e-13 49.1 0.0 3.1 1 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ORY39432.1 - 3.1e-11 42.9 0.1 1e-09 38.0 0.0 2.5 2 0 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 ORY39432.1 - 4e-10 39.3 0.0 4.5e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ORY39432.1 - 1.7e-08 34.0 0.8 2.7e-05 23.5 0.1 3.1 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 ORY39432.1 - 2.3e-07 30.1 0.0 6.3e-07 28.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 ORY39432.1 - 0.0096 15.8 6.6 0.059 13.3 0.3 2.8 2 1 1 3 3 3 1 KR domain adh_short PF00106.25 ORY39432.1 - 0.098 12.1 0.1 2.6 7.5 0.1 2.2 1 1 0 1 1 1 0 short chain dehydrogenase PPR PF01535.20 ORY39433.1 - 1.1e-05 25.3 0.1 0.97 9.8 0.0 4.2 4 0 0 4 4 4 3 PPR repeat PPR_1 PF12854.7 ORY39433.1 - 0.1 12.3 0.0 27 4.6 0.0 3.4 3 0 0 3 3 3 0 PPR repeat NKAIN PF05640.14 ORY39435.1 - 3.9 6.7 11.4 5 6.3 11.4 1.2 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein cNMP_binding PF00027.29 ORY39436.1 - 2.7e-12 46.6 0.0 9.2e-12 44.9 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Mito_carr PF00153.27 ORY39438.1 - 2.8e-43 145.8 7.1 1.4e-20 73.0 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Homeodomain PF00046.29 ORY39489.1 - 8.8e-10 38.3 0.0 2e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY39489.1 - 0.013 15.4 0.2 0.054 13.4 0.0 2.2 2 0 0 2 2 2 0 Homeobox KN domain DUF3562 PF12085.8 ORY39489.1 - 0.025 14.2 0.0 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3562) Cwf_Cwc_15 PF04889.12 ORY39490.1 - 0.005 16.6 3.1 0.0084 15.9 3.1 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Homeodomain PF00046.29 ORY39490.1 - 0.0065 16.3 0.4 0.0065 16.3 0.4 2.4 2 0 0 2 2 2 1 Homeodomain Vasculin PF15337.6 ORY39490.1 - 0.19 12.6 1.8 0.5 11.2 1.8 1.8 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 EF-hand_13 PF17958.1 ORY39491.1 - 1.4e-15 56.8 0.0 3.6e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 ORY39491.1 - 6.4e-13 49.0 0.0 5.1e-12 46.1 0.0 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 ORY39491.1 - 0.00011 21.6 0.1 0.00025 20.4 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 ORY39491.1 - 0.00051 19.8 0.1 0.023 14.6 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 ORY39491.1 - 0.00072 18.9 0.1 0.011 15.3 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 ORY39491.1 - 0.033 14.0 0.6 0.12 12.2 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain pair DUF4746 PF15928.5 ORY39491.1 - 1.4 8.3 4.9 0.58 9.5 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4746) Ysc84 PF04366.12 ORY39492.1 - 8.4e-39 132.3 0.5 1.6e-38 131.3 0.5 1.5 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 ORY39492.1 - 5.5e-12 45.1 0.1 1.2e-11 44.0 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY39492.1 - 9.5e-12 44.6 0.0 2.4e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY39492.1 - 5.9e-11 41.9 0.0 2e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain Glyco_hydro_18 PF00704.28 ORY39492.1 - 9.3e-10 38.7 0.0 1.3e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PGM1_C PF18105.1 ORY39492.1 - 0.15 11.6 0.1 0.32 10.6 0.1 1.5 1 0 0 1 1 1 0 PGM1 C-terminal domain BAG PF02179.16 ORY39493.1 - 0.00025 21.4 3.4 0.11 12.9 0.2 2.3 2 0 0 2 2 2 2 BAG domain ssDNA_TraI_N PF18272.1 ORY39493.1 - 0.0019 18.2 0.3 0.13 12.2 0.1 2.6 2 0 0 2 2 2 1 single-stranded DNA binding TraI N-terminal subdomain SLATT_fungal PF18142.1 ORY39493.1 - 0.0075 16.3 2.4 0.019 14.9 0.4 2.3 2 1 0 2 2 2 1 SMODS and SLOG-associating 2TM effector domain SR-25 PF10500.9 ORY39493.1 - 6.6 6.3 9.8 11 5.6 7.8 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Ribonuclease_T2 PF00445.18 ORY39494.1 - 6.3e-27 95.0 0.3 9.1e-27 94.5 0.3 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Ribonuclease_T2 PF00445.18 ORY39495.1 - 2.3e-24 86.6 0.1 3.4e-24 86.1 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Peptidase_S9_N PF02897.15 ORY39496.1 - 1.5e-92 310.6 0.3 2e-92 310.2 0.3 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 ORY39496.1 - 2.2e-60 203.8 0.0 4.6e-60 202.7 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF4811 PF16069.5 ORY39496.1 - 0.27 11.1 2.6 2.1 8.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4811) Rieske PF00355.26 ORY39497.1 - 2.3e-10 40.3 0.1 3.3e-10 39.8 0.1 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 ORY39497.1 - 0.00086 19.2 0.0 0.0016 18.4 0.0 1.4 1 1 0 1 1 1 1 Rieske-like [2Fe-2S] domain BRE1 PF08647.11 ORY39498.1 - 1.3e-11 44.4 11.8 1.3e-11 44.4 11.8 10.1 2 2 7 11 11 11 3 BRE1 E3 ubiquitin ligase FYVE PF01363.21 ORY39499.1 - 4.1e-23 81.3 20.6 1.5e-17 63.4 5.1 3.0 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 ORY39499.1 - 5.2e-05 22.9 4.9 0.00021 20.9 4.9 2.1 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 ORY39499.1 - 0.02 15.0 3.7 0.02 15.0 3.7 4.4 6 2 0 6 6 6 0 AN1-like Zinc finger Occludin_ELL PF07303.13 ORY39499.1 - 2.5 8.9 7.9 10 6.9 0.2 3.5 3 1 1 4 4 4 0 Occludin homology domain Pam16 PF03656.13 ORY39500.1 - 1.5e-06 28.2 0.1 2.4e-06 27.6 0.1 1.4 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 ORY39500.1 - 7.5e-06 26.0 0.0 1.3e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Phage_TAC_6 PF09550.10 ORY39500.1 - 0.2 12.1 0.3 1.6 9.2 0.1 2.1 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC HET PF06985.11 ORY39501.1 - 5.5e-08 33.3 0.3 2.4e-06 28.0 0.3 2.3 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF647 PF04884.14 ORY39502.1 - 1.7e-47 162.1 0.3 2.3e-47 161.6 0.3 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis MerE PF05052.12 ORY39502.1 - 0.012 15.5 0.1 0.037 13.9 0.1 1.7 1 0 0 1 1 1 0 MerE protein Nop PF01798.18 ORY39503.1 - 1e-87 293.5 0.1 1.9e-87 292.5 0.1 1.5 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 ORY39503.1 - 6.4e-12 45.7 0.1 2.1e-11 44.0 0.1 1.9 1 0 0 1 1 1 1 NOP5NT (NUC127) domain Semialdhyde_dhC PF02774.18 ORY39504.1 - 0.15 12.1 0.1 13 5.8 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain SKG6 PF08693.10 ORY39506.1 - 0.00048 19.5 3.5 0.00077 18.8 3.5 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM61 PF15105.6 ORY39506.1 - 0.073 12.9 0.0 0.1 12.4 0.0 1.3 1 1 0 1 1 1 0 TMEM61 protein family Tetraspanin PF00335.20 ORY39506.1 - 0.13 11.9 1.4 0.19 11.4 1.4 1.1 1 0 0 1 1 1 0 Tetraspanin family SAM_1 PF00536.30 ORY39507.1 - 0.022 15.2 0.1 0.039 14.4 0.1 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 ORY39507.1 - 0.035 14.2 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SKG6 PF08693.10 ORY39507.1 - 0.41 10.1 6.6 0.75 9.3 6.6 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain NOA36 PF06524.12 ORY39508.1 - 0.065 12.5 8.1 0.095 12.0 8.1 1.1 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 ORY39508.1 - 0.86 9.3 2.8 1.6 8.4 2.8 1.3 1 0 0 1 1 1 0 FAM176 family Nop14 PF04147.12 ORY39508.1 - 2.3 6.3 6.1 3.3 5.8 6.1 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-B_dimeris PF09026.10 ORY39508.1 - 3.6 8.0 11.5 7.9 6.9 11.5 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RRM_1 PF00076.22 ORY39509.1 - 1.3e-08 34.5 0.0 2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribonuclease_T2 PF00445.18 ORY39510.1 - 4.8e-26 92.1 0.1 6.6e-26 91.7 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family Ceramidase PF05875.12 ORY39513.1 - 4.1e-69 232.9 15.4 4.8e-69 232.7 15.4 1.0 1 0 0 1 1 1 1 Ceramidase HlyIII PF03006.20 ORY39513.1 - 0.045 13.5 15.6 0.65 9.7 15.6 2.1 1 1 0 1 1 1 0 Haemolysin-III related DUF2109 PF09882.9 ORY39513.1 - 0.26 11.3 2.7 0.62 10.1 2.7 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2109) zf-BED PF02892.15 ORY39515.1 - 0.00021 21.3 0.5 0.00037 20.5 0.5 1.4 1 0 0 1 1 1 1 BED zinc finger zf-C2H2_jaz PF12171.8 ORY39515.1 - 0.0018 18.5 2.1 0.003 17.8 2.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF629 PF04780.12 ORY39515.1 - 0.0083 14.7 0.6 0.011 14.4 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF629) zf-Di19 PF05605.12 ORY39515.1 - 0.012 15.9 4.1 0.018 15.3 4.1 1.2 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 ORY39515.1 - 0.015 16.1 7.3 0.029 15.2 7.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY39515.1 - 0.02 15.4 7.9 0.036 14.5 7.9 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY39515.1 - 0.03 14.8 2.4 0.03 14.8 2.4 2.0 2 0 0 2 2 2 0 Zinc-finger double domain zf-met PF12874.7 ORY39515.1 - 0.045 14.2 2.7 0.093 13.2 2.7 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type LON_substr_bdg PF02190.16 ORY39516.1 - 6.3e-10 39.3 0.0 9.1e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_4 PF15227.6 ORY39516.1 - 3.4e-07 30.3 13.8 0.00047 20.2 10.9 2.7 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 ORY39516.1 - 0.0002 21.1 13.8 0.004 17.0 9.9 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY39516.1 - 0.00079 19.4 14.2 0.012 15.6 10.2 3.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_10 PF16685.5 ORY39516.1 - 0.0011 19.1 5.0 0.0066 16.6 3.3 2.4 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-C3HC4_3 PF13920.6 ORY39516.1 - 0.0014 18.5 8.1 0.0014 18.5 8.1 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY39516.1 - 0.0034 17.7 9.7 0.0034 17.7 9.7 2.8 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY39516.1 - 0.046 13.6 14.7 0.18 11.7 10.6 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_14 PF13428.6 ORY39516.1 - 0.098 13.5 0.5 0.23 12.4 0.5 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-RING_5 PF14634.6 ORY39516.1 - 0.17 11.9 17.2 0.12 12.4 8.4 2.7 2 1 0 2 2 2 0 zinc-RING finger domain zf-RING_11 PF17123.5 ORY39517.1 - 4.4e-11 42.3 1.4 4.4e-11 42.3 1.4 2.3 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 ORY39517.1 - 3.6e-10 40.0 13.3 1.1e-07 32.1 3.8 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 ORY39517.1 - 1.3e-07 31.4 12.5 1.3e-05 24.9 4.2 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY39517.1 - 3.5e-06 26.8 6.9 9.4e-05 22.2 6.9 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY39517.1 - 0.00021 21.2 9.9 0.0003 20.7 3.4 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 ORY39517.1 - 0.00021 21.5 12.0 0.075 13.3 12.0 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 ORY39517.1 - 0.00049 20.0 8.6 0.0018 18.2 8.6 1.9 1 1 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 ORY39517.1 - 0.0085 16.1 8.6 0.35 11.0 8.6 2.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 ORY39517.1 - 0.054 13.4 3.6 0.054 13.4 3.6 2.2 2 0 0 2 2 2 0 PHD-finger zf-C3HC4_3 PF13920.6 ORY39517.1 - 0.15 11.9 9.7 23 5.0 9.7 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 ORY39517.1 - 0.26 10.9 9.0 0.28 10.9 4.5 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 ORY39517.1 - 0.41 10.6 6.8 22 5.0 6.8 2.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 ORY39517.1 - 0.71 9.9 6.5 1 9.3 2.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.8 ORY39517.1 - 1.2 9.4 10.0 2.7 8.2 10.0 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain NADH-G_4Fe-4S_3 PF10588.9 ORY39517.1 - 1.3 8.7 5.5 2.3 7.8 0.2 3.1 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region zf-C3H2C3 PF17122.5 ORY39517.1 - 1.5 8.9 6.2 0.75 9.9 1.6 2.6 2 0 0 2 2 2 0 Zinc-finger DUF3275 PF11679.8 ORY39518.1 - 0.026 14.5 3.9 0.029 14.3 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) LRR_4 PF12799.7 ORY39519.1 - 4.2e-11 42.9 7.3 0.0012 19.3 0.4 4.0 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY39519.1 - 1.3e-06 28.1 1.7 7.5 7.5 0.0 5.8 4 1 1 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 ORY39519.1 - 5.8e-06 26.0 1.4 1.7 8.9 0.0 5.1 5 0 0 5 5 5 2 Leucine Rich repeat LRR_8 PF13855.6 ORY39519.1 - 0.00021 21.0 6.6 0.071 12.9 0.1 4.0 1 1 2 4 4 4 3 Leucine rich repeat Response_reg PF00072.24 ORY39521.1 - 1.9e-18 66.7 0.0 1e-17 64.3 0.0 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 ORY39521.1 - 2.1e-13 50.8 0.0 5.8e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.7 ORY39521.1 - 1.6e-12 47.6 2.9 3.1e-12 46.7 0.2 3.0 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 ORY39521.1 - 2.7e-12 46.7 0.1 2.7e-12 46.7 0.1 3.6 3 1 1 4 4 4 1 PAS fold PAS_4 PF08448.10 ORY39521.1 - 1.9e-06 28.1 0.0 2e-05 24.8 0.0 2.5 1 1 1 2 2 2 1 PAS fold HisKA PF00512.25 ORY39521.1 - 3.2e-06 27.1 0.3 1.4e-05 25.1 0.3 2.2 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 ORY39521.1 - 4.8e-06 26.5 0.2 0.0003 20.7 0.0 3.0 3 0 0 3 3 3 1 PAS domain PET117 PF15786.5 ORY39521.1 - 9.1 6.6 8.8 1.8 8.9 2.0 3.5 2 0 0 2 2 2 0 PET assembly of cytochrome c oxidase, mitochondrial MPC PF03650.13 ORY39522.1 - 8.2e-34 116.1 0.1 1.2e-33 115.6 0.0 1.3 1 1 1 2 2 2 1 Mitochondrial pyruvate carriers SAM_PNT PF02198.16 ORY39523.1 - 0.0024 17.8 0.0 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_1 PF00536.30 ORY39523.1 - 0.066 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Big_9 PF17963.1 ORY39523.1 - 0.073 13.8 1.3 1.2 9.9 0.7 3.1 1 1 1 2 2 2 0 Bacterial Ig domain TMEM154 PF15102.6 ORY39523.1 - 0.1 12.5 0.1 0.26 11.2 0.1 1.7 1 0 0 1 1 1 0 TMEM154 protein family PRIMA1 PF16101.5 ORY39523.1 - 0.14 12.2 0.4 0.35 10.9 0.4 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 PASTA PF03793.19 ORY39526.1 - 0.081 12.8 0.6 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 PASTA domain DUF4210 PF13915.6 ORY39527.1 - 2.4e-17 63.3 0.1 8.8e-17 61.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 ORY39527.1 - 1.7e-14 53.7 0.0 3.1e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation during meiosis CD24 PF14984.6 ORY39529.1 - 2.3 8.5 9.6 0.12 12.6 3.1 2.2 2 1 0 2 2 2 0 CD24 protein Glyco_hydro_31 PF01055.26 ORY39530.1 - 4.8e-56 190.8 0.2 8.3e-51 173.5 0.3 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 31 DUF5110 PF17137.4 ORY39530.1 - 3.5e-09 36.8 0.2 1.8e-08 34.5 0.2 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) DUF4968 PF16338.5 ORY39530.1 - 2.4e-07 31.0 0.7 5.8e-07 29.7 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) DUF2207 PF09972.9 ORY39530.1 - 0.0021 16.9 0.1 0.004 16.0 0.1 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) SH3_2 PF07653.17 ORY39532.1 - 1.6e-06 27.7 0.2 3.2e-06 26.7 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ORY39532.1 - 2.2e-06 27.5 1.1 2.9e-06 27.0 0.3 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 ORY39532.1 - 6.7e-06 25.6 0.1 1.3e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY39533.1 - 1.8e-06 27.5 0.1 3.6e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY39533.1 - 8.7e-06 25.3 0.1 1.6e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY39533.1 - 2.6e-05 24.0 0.2 4.9e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain ASH PF15780.5 ORY39534.1 - 1.8e-64 214.1 49.4 0.0079 16.4 0.0 28.7 28 1 1 29 29 29 17 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 ORY39534.1 - 1.1e-23 83.1 26.1 0.0053 16.8 0.1 20.8 25 2 0 25 25 24 4 Protein of unknown function (DUF1573) PapD-like PF14874.6 ORY39534.1 - 1.2e-18 67.2 1.2 0.48 10.6 0.0 11.6 11 0 0 11 11 11 4 Flagellar-associated PapD-like Motile_Sperm PF00635.26 ORY39534.1 - 1.5e-18 66.6 38.6 0.21 11.5 0.0 18.8 23 0 0 23 23 23 5 MSP (Major sperm protein) domain Hydin_ADK PF17213.3 ORY39534.1 - 4.7e-11 43.3 0.1 6.7e-06 26.5 0.1 2.8 2 0 0 2 2 2 2 Hydin Adenylate kinase-like domain MYCBPAP PF14646.6 ORY39534.1 - 3e-09 36.3 9.1 0.25 10.2 0.0 10.5 10 1 0 11 11 11 1 MYCBP-associated protein family TMEM131_like PF12371.8 ORY39534.1 - 7.7e-07 29.3 22.9 0.14 12.4 0.1 12.4 14 0 0 14 14 13 2 Transmembrane protein 131-like PapD_N PF00345.20 ORY39534.1 - 3.8e-05 23.6 0.1 0.041 13.8 0.0 5.7 5 0 0 5 5 5 1 Pili and flagellar-assembly chaperone, PapD N-terminal domain DUF5001 PF16392.5 ORY39534.1 - 5.2e-05 23.1 12.2 0.12 12.3 0.0 9.8 13 0 0 13 13 13 1 Ig-like domain ADK PF00406.22 ORY39534.1 - 7.9e-05 22.8 1.4 0.07 13.2 0.8 2.8 1 1 1 2 2 2 2 Adenylate kinase Cupredoxin_1 PF13473.6 ORY39534.1 - 0.0045 17.1 0.3 1.7 8.8 0.0 4.5 2 0 0 2 2 2 1 Cupredoxin-like domain AAA PF00004.29 ORY39534.1 - 0.071 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ig_GlcNase PF18368.1 ORY39534.1 - 0.18 12.0 0.2 46 4.2 0.0 4.8 5 0 0 5 5 5 0 Exo-beta-D-glucosaminidase Ig-fold domain TMPIT PF07851.13 ORY39535.1 - 2.3e-67 227.6 3.1 2.4e-66 224.2 0.2 2.0 2 0 0 2 2 2 2 TMPIT-like protein NIT PF08376.10 ORY39535.1 - 0.0078 16.7 0.1 1 9.8 0.1 2.4 2 0 0 2 2 2 2 Nitrate and nitrite sensing Sporozoite_P67 PF05642.11 ORY39535.1 - 0.36 8.9 1.7 0.54 8.3 1.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ecl1 PF12855.7 ORY39536.1 - 5.5e-11 43.9 4.3 6.6e-11 43.7 4.3 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins LRR_8 PF13855.6 ORY39541.1 - 7e-19 67.3 19.4 2.7e-08 33.4 3.2 4.5 4 0 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 ORY39541.1 - 1.2e-09 38.2 23.1 0.00024 21.4 1.5 5.6 2 1 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY39541.1 - 3.6e-09 35.9 31.6 2.2 9.2 1.2 9.2 8 1 1 9 9 9 6 Leucine Rich Repeat FNIP PF05725.12 ORY39541.1 - 5.9e-06 26.4 0.1 0.0033 17.6 0.1 4.1 1 1 0 1 1 1 1 FNIP Repeat LRR_6 PF13516.6 ORY39541.1 - 1.5e-05 24.7 11.6 16 5.8 0.1 6.4 6 0 0 6 6 6 3 Leucine Rich repeat F-box PF00646.33 ORY39541.1 - 0.00016 21.5 0.0 0.00039 20.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY39541.1 - 0.013 15.3 0.2 0.035 14.0 0.0 1.9 2 0 0 2 2 2 0 F-box-like TauD PF02668.16 ORY39542.1 - 1e-48 166.5 0.0 1.3e-48 166.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF2207 PF09972.9 ORY39543.1 - 0.035 12.9 0.8 0.038 12.8 0.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4418 PF14387.6 ORY39543.1 - 0.19 11.9 7.0 0.044 14.0 2.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4418) DUF202 PF02656.15 ORY39543.1 - 1.2 9.6 6.2 0.7 10.4 2.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Phage_holin_3_6 PF07332.11 ORY39543.1 - 6.3 6.9 8.4 1.5 8.8 5.0 1.6 1 1 1 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Rpp20 PF12328.8 ORY39544.1 - 1.3e-15 57.5 3.3 4.2e-11 43.0 1.5 2.1 1 1 1 2 2 2 2 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 ORY39544.1 - 9.7e-14 50.9 0.6 1.4e-13 50.4 0.2 1.5 2 0 0 2 2 2 1 Alba SIP1 PF04938.12 ORY39545.1 - 0.09 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Patatin PF01734.22 ORY39545.1 - 0.17 12.0 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Patatin-like phospholipase UPF0193 PF05250.11 ORY39546.1 - 4.3e-38 131.3 6.7 1.2e-18 67.8 1.1 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0193) Snf7 PF03357.21 ORY39547.1 - 5.2e-13 49.0 16.9 7.8e-13 48.4 16.9 1.1 1 0 0 1 1 1 1 Snf7 DMSP_lyase PF16867.5 ORY39547.1 - 0.0044 16.7 0.1 0.0092 15.6 0.1 1.5 1 0 0 1 1 1 1 Dimethlysulfonioproprionate lyase Ist1 PF03398.14 ORY39547.1 - 0.01 15.8 6.4 0.014 15.3 6.4 1.2 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway ANAPC2 PF08672.11 ORY39547.1 - 1.1 9.8 5.2 30 5.2 4.0 3.0 2 1 0 2 2 2 0 Anaphase promoting complex (APC) subunit 2 Ribosomal_L37 PF08561.10 ORY39547.1 - 1.8 9.1 7.9 1.2 9.6 5.4 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L37 DHHC PF01529.20 ORY39548.1 - 2.2e-34 118.4 10.9 2.2e-34 118.4 10.9 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF5381 PF17353.2 ORY39548.1 - 0.61 9.8 3.4 1.2 8.9 3.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5381) DUF202 PF02656.15 ORY39548.1 - 4.3 7.9 6.2 5.4 7.5 0.1 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF202) cNMP_binding PF00027.29 ORY39549.1 - 3.7e-18 65.4 0.1 8.4e-18 64.2 0.1 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Glyco_hydro_26 PF02156.15 ORY39550.1 - 1.2e-09 38.1 2.9 1.7e-09 37.5 2.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Mucin PF01456.17 ORY39550.1 - 0.26 11.3 21.8 0.22 11.5 13.7 2.5 2 0 0 2 2 2 0 Mucin-like glycoprotein Ribosomal_L14 PF00238.19 ORY39551.1 - 8.2e-41 138.9 1.8 9.2e-41 138.7 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e PAAR_motif PF05488.13 ORY39551.1 - 0.045 13.9 0.3 0.069 13.3 0.3 1.3 1 0 0 1 1 1 0 PAAR motif CS PF04969.16 ORY39552.1 - 5.9e-18 65.7 0.5 5.9e-18 65.7 0.5 1.8 3 0 0 3 3 3 1 CS domain T4bSS_IcmS PF12608.8 ORY39552.1 - 0.025 14.9 0.1 0.063 13.6 0.1 1.7 1 1 0 1 1 1 0 Type IVb secretion, IcmS, effector-recruitment FAD_binding_4 PF01565.23 ORY39552.1 - 0.11 12.2 0.0 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain LRR_8 PF13855.6 ORY39553.1 - 1.6e-22 79.0 30.1 7e-09 35.3 0.5 7.2 5 2 2 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 ORY39553.1 - 2.4e-20 72.3 45.3 6.1e-07 29.7 0.4 8.8 8 1 1 9 9 9 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY39553.1 - 1.9e-08 33.7 26.2 0.21 11.7 0.1 10.7 9 2 1 10 10 10 4 Leucine Rich repeat LRR_9 PF14580.6 ORY39553.1 - 4.8e-06 26.2 8.2 0.0065 16.0 0.6 4.4 1 1 3 4 4 4 2 Leucine-rich repeat LRR_1 PF00560.33 ORY39553.1 - 5.2e-06 26.3 31.8 0.32 11.7 0.7 10.5 9 3 1 10 10 10 4 Leucine Rich Repeat Ribosomal_L19e PF01280.20 ORY39555.1 - 1.7e-57 193.6 5.3 1.7e-57 193.6 5.3 1.7 1 1 1 2 2 2 1 Ribosomal protein L19e Lant_dehydr_C PF14028.6 ORY39555.1 - 0.0047 16.5 0.9 0.006 16.2 0.2 1.4 1 1 0 1 1 1 1 Lantibiotic biosynthesis dehydratase C-term DEDD_Tnp_IS110 PF01548.17 ORY39555.1 - 0.034 14.0 1.0 0.07 13.0 1.0 1.6 1 0 0 1 1 1 0 Transposase Mon2_C PF16206.5 ORY39555.1 - 0.14 10.2 0.1 0.16 10.1 0.1 1.0 1 0 0 1 1 1 0 C-terminal region of Mon2 protein Maf1 PF09174.10 ORY39557.1 - 3.7e-52 177.0 0.0 4.9e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator NAT PF04768.13 ORY39557.1 - 0.091 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase FCH PF00611.23 ORY39558.1 - 3.3e-13 49.7 0.1 1e-12 48.1 0.1 1.9 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 ORY39558.1 - 1.1e-10 41.2 0.1 2.7e-10 39.9 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY39558.1 - 9.2e-09 34.8 0.0 1.7e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY39558.1 - 3.5e-07 29.8 0.1 6.1e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.10 ORY39558.1 - 0.0024 17.5 0.9 0.0024 17.5 0.9 2.4 1 1 1 2 2 2 1 Vps5 C terminal like ALMT PF11744.8 ORY39558.1 - 1.2 7.9 7.3 1.7 7.4 7.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter tRNA-synt_2 PF00152.20 ORY39559.1 - 2.3e-77 260.2 0.0 3.3e-77 259.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORY39559.1 - 7.5e-11 41.9 0.0 2.1e-10 40.4 0.0 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ORY39559.1 - 1.6e-06 27.8 0.0 0.014 14.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF4203 PF13886.6 ORY39560.1 - 2.7e-16 59.9 30.0 3.3e-16 59.5 30.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Cmc1 PF08583.10 ORY39561.1 - 0.00033 20.6 2.1 0.00062 19.7 2.1 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Cys_Met_Meta_PP PF01053.20 ORY39562.1 - 4.1e-134 446.9 0.0 4.8e-134 446.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ORY39562.1 - 1.8e-05 24.1 0.0 3.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Coat_X PF07552.11 ORY39562.1 - 0.0064 16.3 0.1 0.016 15.1 0.1 1.6 1 0 0 1 1 1 1 Spore Coat Protein X and V domain Methyltransf_29 PF03141.16 ORY39562.1 - 0.0086 14.7 0.0 0.013 14.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Met_gamma_lyase PF06838.11 ORY39562.1 - 0.029 12.9 0.0 0.039 12.5 0.0 1.3 1 0 0 1 1 1 0 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 ORY39562.1 - 0.096 12.0 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family PapA_C PF16911.5 ORY39562.1 - 0.15 12.2 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus zf-Tim10_DDP PF02953.15 ORY39564.1 - 9e-20 70.1 0.4 1.1e-19 69.9 0.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger OMS28_porin PF03532.13 ORY39564.1 - 0.058 12.6 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 OMS28 porin Condensin2nSMC PF12422.8 ORY39564.1 - 0.12 12.6 0.1 0.16 12.2 0.1 1.3 1 1 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit Ribosomal_S7 PF00177.21 ORY39565.1 - 1.5e-35 122.1 3.7 1.7e-35 121.8 3.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e LRR_6 PF13516.6 ORY39566.1 - 4.3e-06 26.4 4.5 2.3 8.5 0.0 6.4 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 ORY39566.1 - 0.0063 16.9 6.0 5.6 7.5 0.0 5.7 6 0 0 6 6 6 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY39566.1 - 4.4 8.2 11.7 34 5.5 0.0 6.5 8 1 0 8 8 8 0 Leucine Rich Repeat Cytidylate_kin PF02224.18 ORY39567.1 - 6.6e-56 189.4 1.1 7.6e-56 189.2 1.1 1.0 1 0 0 1 1 1 1 Cytidylate kinase AAA_18 PF13238.6 ORY39567.1 - 7.4e-05 23.3 0.0 0.00083 19.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY39567.1 - 0.00044 20.4 0.1 0.0083 16.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.6 ORY39567.1 - 0.029 14.5 0.1 0.091 12.9 0.1 1.9 1 1 0 1 1 1 0 Cytidylate kinase-like family ANTH PF07651.16 ORY39568.1 - 3.4e-52 177.2 1.1 4.1e-52 176.9 1.1 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 ORY39568.1 - 2.1e-05 24.5 0.4 6e-05 23.1 0.4 1.7 1 0 0 1 1 1 1 ENTH domain Adaptin_N PF01602.20 ORY39568.1 - 0.095 11.2 0.3 0.14 10.7 0.3 1.2 1 0 0 1 1 1 0 Adaptin N terminal region cNMP_binding PF00027.29 ORY39569.1 - 9.7e-18 64.0 0.0 1.7e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF3729 PF12526.8 ORY39569.1 - 0.034 15.7 0.2 0.034 15.7 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3729) LRR_4 PF12799.7 ORY39569.1 - 0.26 11.8 11.0 2.3 8.7 0.1 3.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) WbqC PF08889.11 ORY39571.1 - 0.039 13.9 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 WbqC-like protein family RPAP1_C PF08620.10 ORY39571.1 - 0.1 12.7 0.2 0.37 10.9 0.2 1.9 1 0 0 1 1 1 0 RPAP1-like, C-terminal zf-C4_ClpX PF06689.13 ORY39571.1 - 0.17 11.8 0.0 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 ClpX C4-type zinc finger PEP-utilisers_N PF05524.13 ORY39572.1 - 0.026 14.7 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal PI3_PI4_kinase PF00454.27 ORY39573.1 - 2e-47 162.1 0.0 1.1e-46 159.7 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF4042 PF13251.6 ORY39573.1 - 0.064 12.9 1.9 0.16 11.7 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4042) Thymidylate_kin PF02223.17 ORY39574.1 - 3.1e-44 150.9 0.0 3.6e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 ORY39574.1 - 0.0014 18.9 0.0 0.0018 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain PPK2 PF03976.14 ORY39574.1 - 0.012 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Polyphosphate kinase 2 (PPK2) AAA_17 PF13207.6 ORY39574.1 - 0.033 14.6 0.0 0.079 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.10 ORY39574.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 CIDE-N PF02017.15 ORY39575.1 - 0.28 11.2 4.0 20 5.3 0.0 3.6 4 0 0 4 4 4 0 CIDE-N domain KilA-N PF04383.13 ORY39576.1 - 0.00022 21.0 0.1 0.00028 20.7 0.1 1.2 1 0 0 1 1 1 1 KilA-N domain UPF0160 PF03690.13 ORY39577.1 - 2.7e-117 392.0 0.0 3.1e-117 391.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Prefoldin PF02996.17 ORY39578.1 - 3.2e-28 98.0 1.0 4.5e-28 97.6 0.5 1.4 1 1 0 1 1 1 1 Prefoldin subunit End3 PF12761.7 ORY39578.1 - 0.003 17.7 0.7 0.007 16.6 0.6 1.7 1 1 1 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 DUF1664 PF07889.12 ORY39578.1 - 0.023 14.7 0.2 2.9 8.0 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) LMP PF04778.12 ORY39578.1 - 0.024 14.5 0.1 7.1 6.5 0.1 2.2 2 0 0 2 2 2 0 LMP repeated region Lebercilin PF15619.6 ORY39578.1 - 0.1 12.2 2.5 0.27 10.9 0.2 2.0 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Prefoldin_2 PF01920.20 ORY39578.1 - 0.23 11.5 2.7 1.7 8.7 0.7 2.4 1 1 0 2 2 2 0 Prefoldin subunit FlaC_arch PF05377.11 ORY39578.1 - 0.25 11.8 1.2 4 7.9 0.2 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Mucin PF01456.17 ORY39579.1 - 0.018 15.0 24.7 0.041 13.9 24.7 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein HTH_21 PF13276.6 ORY39580.1 - 0.091 12.9 1.8 0.2 11.8 0.1 2.4 3 0 0 3 3 3 0 HTH-like domain Stc1 PF12898.7 ORY39580.1 - 7.9 7.1 10.0 5.8 7.5 5.1 3.2 3 1 0 3 3 3 0 Stc1 domain zf-RING_UBOX PF13445.6 ORY39580.1 - 9.1 6.4 15.2 20 5.3 3.9 4.5 4 0 0 4 4 4 0 RING-type zinc-finger CRAL_TRIO PF00650.20 ORY39582.1 - 1.8e-29 102.5 0.0 3.1e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 ORY39582.1 - 9e-06 25.9 0.0 1.2e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain EspB_PE PF18625.1 ORY39582.1 - 0.11 13.0 0.3 0.58 10.7 0.0 2.1 1 1 1 2 2 2 0 ESX-1 secreted protein B PE domain MFS_1 PF07690.16 ORY39583.1 - 5.4e-21 74.9 46.1 7.1e-21 74.5 46.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Esterase PF00756.20 ORY39583.1 - 0.17 11.5 0.4 0.26 10.9 0.4 1.2 1 0 0 1 1 1 0 Putative esterase Pkinase PF00069.25 ORY39585.1 - 1.6e-20 73.6 0.0 4.6e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY39585.1 - 1.7e-15 57.0 0.0 2e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY39585.1 - 0.0019 18.2 0.8 0.0049 16.8 0.8 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY39585.1 - 0.018 13.9 0.0 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RabGAP-TBC PF00566.18 ORY39587.1 - 1.8e-38 132.4 0.0 2.6e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EXS PF03124.14 ORY39588.1 - 5.5e-80 269.2 10.6 8.8e-80 268.5 10.6 1.3 1 1 0 1 1 1 1 EXS family Pkinase PF00069.25 ORY39589.1 - 1.5e-56 191.7 0.0 1.8e-56 191.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY39589.1 - 1.3e-36 126.3 0.0 1.5e-36 126.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY39589.1 - 1.8e-06 27.5 0.0 2.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY39589.1 - 0.0062 15.4 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 ORY39589.1 - 0.036 13.7 0.2 1.8 8.2 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 ORY39589.1 - 0.15 11.9 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Herpes_UL51 PF04540.13 ORY39590.1 - 0.058 13.1 0.0 0.068 12.9 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL51 protein Pkinase PF00069.25 ORY39591.1 - 1.2e-69 234.6 0.0 1.5e-69 234.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY39591.1 - 1.6e-38 132.5 0.0 2.1e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY39591.1 - 8.9e-07 28.5 0.1 1.9e-06 27.4 0.1 1.6 1 1 0 1 1 1 1 Kinase-like WH1 PF00568.23 ORY39591.1 - 0.045 13.7 0.4 0.084 12.8 0.4 1.4 1 0 0 1 1 1 0 WH1 domain Haspin_kinase PF12330.8 ORY39591.1 - 0.054 12.4 0.2 0.078 11.9 0.2 1.1 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 ORY39591.1 - 0.18 11.7 0.0 11 5.9 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family GDPD PF03009.17 ORY39592.1 - 9.4e-11 41.9 0.0 2.2e-10 40.7 0.0 1.7 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family V-SNARE_C PF12352.8 ORY39593.1 - 1.1e-11 44.9 3.8 3.5e-10 40.0 1.8 2.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 ORY39593.1 - 3.7e-07 30.4 2.9 3.7e-07 30.4 2.9 3.0 2 2 2 4 4 4 1 Vesicle transport v-SNARE protein N-terminus Synaptobrevin PF00957.21 ORY39593.1 - 0.029 14.2 1.5 0.078 12.8 0.2 2.2 2 0 0 2 2 2 0 Synaptobrevin MAP65_ASE1 PF03999.12 ORY39594.1 - 8.8e-16 57.7 9.3 1e-15 57.5 9.3 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF743 PF05332.11 ORY39594.1 - 0.12 12.4 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF743) Glyco_hydro_18 PF00704.28 ORY39595.1 - 1.5e-12 47.9 1.5 1.5e-12 47.9 1.5 2.5 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.14 ORY39595.1 - 0.00028 21.3 3.3 0.00028 21.3 3.3 3.2 3 0 0 3 3 3 1 Carbohydrate binding domain Mucin PF01456.17 ORY39595.1 - 0.032 14.2 22.1 0.06 13.3 22.1 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein FSA_C PF10479.9 ORY39595.1 - 2.2 6.3 9.4 2.8 5.9 9.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus NIF PF03031.18 ORY39596.1 - 2.8e-56 189.6 0.7 3.3e-56 189.4 0.7 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 ORY39596.1 - 0.011 16.1 0.1 0.12 12.7 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 ORY39597.1 - 4.3e-62 209.9 0.0 1e-61 208.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY39597.1 - 2.9e-37 128.3 0.0 1.8e-36 125.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY39597.1 - 4.5e-05 22.9 0.0 0.00011 21.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORY39597.1 - 0.0017 18.3 0.1 0.021 14.8 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF927 PF06048.11 ORY39597.1 - 0.042 13.4 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF927) Haspin_kinase PF12330.8 ORY39597.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain SHE3 PF17078.5 ORY39598.1 - 0.0075 16.0 3.1 0.0075 16.0 3.1 1.7 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 DUF3275 PF11679.8 ORY39598.1 - 0.044 13.7 0.1 0.044 13.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) bZIP_1 PF00170.21 ORY39598.1 - 0.046 13.8 3.4 2.3 8.4 0.3 2.5 2 0 0 2 2 2 0 bZIP transcription factor ZapB PF06005.12 ORY39598.1 - 0.11 13.0 4.3 0.41 11.1 4.3 2.0 1 0 0 1 1 1 0 Cell division protein ZapB Nnf1 PF03980.14 ORY39598.1 - 0.2 12.0 6.6 0.1 13.0 3.7 2.0 2 0 0 2 2 2 0 Nnf1 DUF4472 PF14739.6 ORY39598.1 - 0.75 10.6 7.3 0.17 12.7 3.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4472) YabA PF06156.13 ORY39598.1 - 0.81 10.4 6.2 0.23 12.1 2.9 1.8 2 0 0 2 2 2 0 Initiation control protein YabA HALZ PF02183.18 ORY39598.1 - 1.2 9.4 4.4 17 5.7 0.4 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper NRBF2 PF08961.10 ORY39598.1 - 1.6 8.3 11.6 0.97 9.0 0.5 3.2 2 1 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator ADIP PF11559.8 ORY39598.1 - 3.8 7.6 10.8 0.45 10.6 6.1 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Motile_Sperm PF00635.26 ORY39599.1 - 2.3e-09 37.1 0.4 4.4e-09 36.2 0.4 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain DUF1573 PF07610.11 ORY39599.1 - 0.014 15.5 0.2 0.014 15.5 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1573) RAMPs PF03787.15 ORY39600.1 - 2.1 8.4 8.3 3.9 7.4 5.2 2.1 1 1 1 2 2 2 0 RAMP superfamily fn3 PF00041.21 ORY39601.1 - 0.035 14.4 0.0 0.22 11.9 0.0 2.2 2 0 0 2 2 2 0 Fibronectin type III domain Ribosomal_60s PF00428.19 ORY39601.1 - 0.93 10.1 10.8 0.13 12.8 6.6 1.9 2 1 0 2 2 2 0 60s Acidic ribosomal protein DUF4200 PF13863.6 ORY39602.1 - 0.00041 20.7 19.7 0.00041 20.7 19.7 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) Sds3 PF08598.11 ORY39602.1 - 0.0015 18.6 0.9 0.0015 18.6 0.9 2.2 1 1 1 2 2 2 1 Sds3-like TPR_MLP1_2 PF07926.12 ORY39602.1 - 0.021 14.9 9.4 0.021 14.9 9.4 2.7 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF3584 PF12128.8 ORY39602.1 - 0.38 8.2 18.9 0.48 7.9 18.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Lectin_N PF03954.14 ORY39602.1 - 0.69 9.7 5.0 0.5 10.1 1.5 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Golgin_A5 PF09787.9 ORY39602.1 - 2.2 7.7 23.5 0.78 9.1 15.2 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 Fez1 PF06818.15 ORY39602.1 - 2.5 8.5 22.3 3.5 8.0 22.3 1.2 1 0 0 1 1 1 0 Fez1 PRKG1_interact PF15898.5 ORY39602.1 - 4.9 8.1 23.8 0.72 10.8 11.6 2.3 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Fmp27_WPPW PF10359.9 ORY39602.1 - 5.9 5.6 17.3 18 4.0 17.2 1.6 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain ZapD PF07072.11 ORY39602.1 - 7.4 6.3 11.2 15 5.3 0.4 2.2 2 0 0 2 2 2 0 Cell division protein GRAM PF02893.20 ORY39604.1 - 4.5e-11 42.6 0.1 1.2e-10 41.3 0.1 1.6 1 0 0 1 1 1 1 GRAM domain HlyIII PF03006.20 ORY39605.1 - 3.9e-45 154.3 24.7 1.2e-43 149.5 24.7 2.2 1 1 0 1 1 1 1 Haemolysin-III related Cpn60_TCP1 PF00118.24 ORY39606.1 - 9e-159 529.2 2.6 1.2e-158 528.8 2.6 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Acyl-CoA_dh_M PF02770.19 ORY39607.1 - 1.1e-08 35.2 0.0 2.2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORY39607.1 - 9.9e-05 23.0 0.0 0.00027 21.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_ox_N PF14749.6 ORY39607.1 - 0.00024 21.7 0.0 0.0044 17.6 0.0 2.3 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Pkinase PF00069.25 ORY39608.1 - 2.6e-21 76.2 0.0 4.6e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY39608.1 - 3.1e-14 52.9 0.0 5e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY39608.1 - 8e-06 24.9 0.1 1.6e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORY39608.1 - 0.052 12.9 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY39608.1 - 0.072 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family TEX12 PF15219.6 ORY39609.1 - 0.26 11.6 1.3 10 6.5 0.0 2.8 3 0 0 3 3 3 0 Testis-expressed 12 MIT PF04212.18 ORY39610.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain PDEase_I PF00233.19 ORY39611.1 - 1.4e-84 283.5 4.0 1.9e-84 283.1 4.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase cNMP_binding PF00027.29 ORY39612.1 - 5.8e-18 64.8 0.0 1.4e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain YqfD PF06898.11 ORY39612.1 - 0.02 13.7 0.2 0.034 13.0 0.2 1.3 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD SCAMP PF04144.13 ORY39614.1 - 2.3e-43 148.5 18.3 2.7e-43 148.3 18.3 1.1 1 0 0 1 1 1 1 SCAMP family Proteasome PF00227.26 ORY39615.1 - 3e-31 108.4 0.0 3.6e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Lipase_3 PF01764.25 ORY39617.1 - 5.8e-10 39.2 0.0 1.5e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORY39617.1 - 0.14 12.7 0.1 0.46 11.1 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2891 PF11199.8 ORY39617.1 - 0.18 10.7 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2891) UCR_Fe-S_N PF10399.9 ORY39617.1 - 2.2 7.7 5.6 0.43 10.0 1.7 1.9 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Sec10 PF07393.11 ORY39618.1 - 0.011 14.2 0.2 0.02 13.4 0.2 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec10 PsbT PF01405.17 ORY39618.1 - 0.096 12.5 1.1 0.27 11.1 1.1 1.8 1 0 0 1 1 1 0 Photosystem II reaction centre T protein zf-RING_2 PF13639.6 ORY39620.1 - 9.8e-08 32.2 11.2 2e-07 31.3 11.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 ORY39620.1 - 9.2e-07 28.7 13.3 1.5e-06 28.1 13.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY39620.1 - 1.2e-06 28.2 14.0 2e-06 27.6 14.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY39620.1 - 2.3e-06 27.3 11.5 5e-06 26.3 11.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY39620.1 - 7.7e-06 25.8 10.4 1.5e-05 24.9 10.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 ORY39620.1 - 0.00019 21.2 10.2 0.00035 20.4 10.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 ORY39620.1 - 0.0003 21.0 8.1 0.0003 21.0 8.1 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 ORY39620.1 - 0.0023 18.1 10.5 0.0054 16.9 10.6 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 ORY39620.1 - 0.0026 17.6 4.8 0.0048 16.7 4.8 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Nse PF11789.8 ORY39620.1 - 0.0039 17.0 6.9 0.0076 16.0 6.9 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 ORY39620.1 - 0.0054 16.8 5.0 0.0054 16.8 5.0 1.7 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 ORY39620.1 - 0.016 14.9 9.6 0.029 14.2 9.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2630 PF10944.8 ORY39620.1 - 0.021 15.3 0.3 0.043 14.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) zf-RING_11 PF17123.5 ORY39620.1 - 0.13 12.1 8.1 0.27 11.0 8.1 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.5 ORY39620.1 - 0.24 11.6 6.5 0.46 10.6 6.5 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-UDP PF14569.6 ORY39620.1 - 0.37 10.9 5.8 0.76 9.9 5.8 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger Utp14 PF04615.13 ORY39620.1 - 2 6.9 6.5 2.4 6.6 6.5 1.1 1 0 0 1 1 1 0 Utp14 protein DZR PF12773.7 ORY39620.1 - 2.2 8.4 9.4 7.5 6.7 9.7 1.8 1 1 0 1 1 1 0 Double zinc ribbon TFIIE-A_C PF11521.8 ORY39620.1 - 6.3 7.2 8.9 0.1 12.9 1.3 2.0 2 0 0 2 2 1 0 C-terminal general transcription factor TFIIE alpha Na_trans_assoc PF06512.13 ORY39621.1 - 0.014 15.7 0.8 0.018 15.3 0.8 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated GET2 PF08690.10 ORY39621.1 - 5.2 6.6 7.5 0.62 9.7 3.1 1.6 1 1 1 2 2 2 0 GET complex subunit GET2 Melibiase_2 PF16499.5 ORY39622.1 - 5.3e-71 239.1 1.2 8.4e-71 238.4 1.2 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 ORY39622.1 - 8.3e-09 35.4 0.3 8.3e-09 35.4 0.3 2.3 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain DnaJ PF00226.31 ORY39622.1 - 2.6e-07 30.7 0.3 2e-06 27.8 0.7 2.1 2 0 0 2 2 2 1 DnaJ domain Melibiase PF02065.18 ORY39622.1 - 5.2e-06 25.7 0.2 1.1e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Melibiase Melibiase_2 PF16499.5 ORY39623.1 - 1.8e-56 191.4 0.7 2.4e-56 191.0 0.7 1.2 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 ORY39623.1 - 1.3e-14 54.0 0.0 3.4e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Malt_amylase_C PF16657.5 ORY39623.1 - 0.048 13.8 0.0 0.69 10.1 0.0 2.3 1 1 1 2 2 2 0 Maltogenic Amylase, C-terminal domain E1-N PF14463.6 ORY39624.1 - 0.072 12.9 1.3 5.7 6.7 1.3 2.2 1 1 0 1 1 1 0 E1 N-terminal domain Melibiase_2 PF16499.5 ORY39625.1 - 1.6e-71 240.8 3.0 2.4e-71 240.2 3.0 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 ORY39625.1 - 1.9e-11 43.8 0.4 5e-11 42.5 0.1 1.9 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 ORY39625.1 - 1.1e-06 27.9 0.0 2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Melibiase Melibiase_2 PF16499.5 ORY39626.1 - 3e-72 243.2 1.2 4.4e-72 242.6 1.2 1.2 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 ORY39626.1 - 3e-11 43.2 0.1 7.1e-11 42.0 0.1 1.6 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 ORY39626.1 - 0.00018 20.6 0.0 0.00039 19.5 0.0 1.5 1 0 0 1 1 1 1 Melibiase Kinesin PF00225.23 ORY39627.1 - 2.9e-96 322.3 0.1 4.2e-96 321.8 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY39627.1 - 3.9e-30 104.8 0.0 9.3e-30 103.5 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding AAA_19 PF13245.6 ORY39627.1 - 0.016 15.5 0.2 1.8 8.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ORY39627.1 - 0.021 14.5 0.1 0.08 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain PBP1_TM PF14812.6 ORY39627.1 - 0.11 12.9 6.2 0.28 11.6 6.2 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BST2 PF16716.5 ORY39627.1 - 0.2 12.3 2.7 0.48 11.1 1.5 2.3 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 DUF4637 PF15470.6 ORY39627.1 - 0.28 10.9 4.6 0.55 9.9 4.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) PRKG1_interact PF15898.5 ORY39627.1 - 4.6 8.2 6.7 9.3 7.2 1.6 3.4 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Mitoc_mL59 PF18126.1 ORY39629.1 - 9.9e-11 42.1 0.3 1.2e-10 41.7 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 CR6_interact PF10147.9 ORY39629.1 - 0.0077 16.0 6.3 0.012 15.4 6.3 1.2 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 STAC2_u1 PF16664.5 ORY39629.1 - 0.031 14.7 0.8 0.037 14.5 0.8 1.2 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 UBA PF00627.31 ORY39630.1 - 1.9e-07 30.9 1.4 0.00058 19.7 0.1 2.9 3 0 0 3 3 3 2 UBA/TS-N domain HOIP-UBA PF16678.5 ORY39630.1 - 0.0067 16.4 0.1 0.24 11.4 0.0 2.1 2 0 0 2 2 2 1 HOIP UBA domain pair DPPIV_N PF00930.21 ORY39631.1 - 6.7e-90 301.4 0.0 1.3e-89 300.4 0.0 1.5 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 ORY39631.1 - 2.7e-46 157.7 0.2 4.4e-46 157.0 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ORY39631.1 - 3.4e-10 40.0 1.0 1.6e-09 37.8 0.4 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 ORY39631.1 - 9.7e-06 25.4 0.0 2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY39631.1 - 4.4e-05 24.2 0.1 0.00017 22.3 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 ORY39631.1 - 0.00011 21.8 0.0 0.00021 20.8 0.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_3 PF07859.13 ORY39631.1 - 0.00013 21.9 0.1 0.00052 19.9 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 ORY39631.1 - 0.00056 19.5 0.1 0.0021 17.7 0.1 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.12 ORY39631.1 - 0.0055 15.4 0.0 0.02 13.6 0.0 1.9 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 ORY39631.1 - 0.012 14.9 0.1 0.2 10.9 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S28 PF05577.12 ORY39631.1 - 0.013 14.3 0.1 0.022 13.6 0.1 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 PD40 PF07676.12 ORY39631.1 - 0.03 14.3 0.1 0.64 10.0 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Baculo_PP31 PF05311.11 ORY39632.1 - 7.6 5.9 12.4 39 3.6 12.4 2.0 1 1 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) SRP-alpha_N PF04086.13 ORY39632.1 - 7.7 6.3 13.2 12 5.7 13.2 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SSXT PF05030.12 ORY39633.1 - 0.038 13.6 0.1 0.061 13.0 0.1 1.3 1 0 0 1 1 1 0 SSXT protein (N-terminal region) AAA PF00004.29 ORY39634.1 - 0.0018 18.7 0.1 0.01 16.2 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY39634.1 - 0.081 13.3 0.1 0.23 11.8 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain E1-E2_ATPase PF00122.20 ORY39637.1 - 5.1e-47 159.7 1.3 5.1e-47 159.7 1.3 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY39637.1 - 8.4e-20 71.2 7.9 1.5e-17 63.9 3.3 3.7 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY39637.1 - 2.5e-17 63.9 0.0 6.2e-08 33.2 0.0 2.7 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY39637.1 - 3.6e-14 52.2 0.0 8.6e-14 51.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 ORY39637.1 - 3.9e-14 52.5 0.0 7.8e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY39637.1 - 0.0043 16.8 0.5 0.077 12.7 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Imm12 PF15560.6 ORY39637.1 - 0.034 14.1 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 12 OprF PF05736.11 ORY39637.1 - 0.087 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 OprF membrane domain DUF2686 PF10887.8 ORY39637.1 - 0.1 11.6 0.2 0.19 10.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) Lactamase_B_2 PF12706.7 ORY39638.1 - 0.00012 21.7 0.0 0.00026 20.6 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.14 ORY39638.1 - 0.00066 19.8 0.1 0.002 18.3 0.1 1.8 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.27 ORY39638.1 - 0.047 13.7 0.1 0.19 11.7 0.1 1.9 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily E1-E2_ATPase PF00122.20 ORY39639.1 - 2.3e-48 164.1 1.9 4.3e-48 163.2 1.9 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY39639.1 - 1.2e-20 74.0 14.0 1.2e-17 64.2 2.2 3.2 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY39639.1 - 2.4e-18 67.2 0.2 1.6e-15 58.0 0.2 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY39639.1 - 2.8e-13 49.7 0.0 7.3e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY39639.1 - 0.0015 18.3 0.6 0.064 13.0 0.4 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2686 PF10887.8 ORY39639.1 - 0.071 12.1 0.2 0.16 10.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) HAD PF12710.7 ORY39639.1 - 0.076 13.4 0.1 0.73 10.2 0.1 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase OprF PF05736.11 ORY39639.1 - 0.08 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 OprF membrane domain HRG PF16954.5 ORY39639.1 - 3.1 8.3 6.0 2 8.9 2.5 2.6 2 0 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Myb_DNA-binding PF00249.31 ORY39640.1 - 4.6e-06 26.7 0.3 4.6e-06 26.7 0.3 2.8 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY39640.1 - 3.9e-05 23.8 2.5 0.00015 22.0 0.1 3.0 4 0 0 4 4 4 1 Myb-like DNA-binding domain DUF966 PF06136.13 ORY39640.1 - 0.0092 15.7 10.8 0.013 15.2 10.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF966) SANT_DAMP1_like PF16282.5 ORY39640.1 - 0.029 14.5 0.0 0.064 13.5 0.0 1.5 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 V-ATPase_H_N PF03224.14 ORY39640.1 - 0.051 12.9 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 V-ATPase subunit H Cwf_Cwc_15 PF04889.12 ORY39641.1 - 0.00032 20.5 1.9 0.00086 19.1 1.9 1.7 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Myb_DNA-binding PF00249.31 ORY39641.1 - 0.00049 20.2 0.1 0.0011 19.1 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain GEMIN8 PF15348.6 ORY39641.1 - 0.048 14.0 1.2 0.15 12.3 1.2 1.9 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Myb_DNA-bind_6 PF13921.6 ORY39641.1 - 0.1 12.9 0.1 0.23 11.8 0.1 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain Syntaxin-18_N PF10496.9 ORY39641.1 - 8.9 6.6 8.7 1.7 9.0 1.3 3.2 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Ribosomal_L36e PF01158.18 ORY39643.1 - 2e-43 146.6 1.9 2.3e-43 146.4 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Pkinase PF00069.25 ORY39645.1 - 3e-59 200.5 0.0 4.1e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY39645.1 - 6.9e-45 153.3 0.0 1.1e-44 152.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY39645.1 - 5.6e-05 22.6 0.1 0.0049 16.2 0.2 2.5 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 ORY39645.1 - 0.0018 18.3 0.0 0.0049 16.8 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family PI3K_1B_p101 PF10486.9 ORY39645.1 - 0.13 10.0 3.8 0.18 9.6 3.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit SDA1 PF05285.12 ORY39645.1 - 6.6 6.1 10.7 9.1 5.6 10.7 1.1 1 0 0 1 1 1 0 SDA1 NOA36 PF06524.12 ORY39645.1 - 6.8 5.9 10.3 10 5.3 10.3 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 ORY39645.1 - 7.9 4.5 10.9 11 4.1 10.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF563 PF04577.14 ORY39646.1 - 4.1e-13 50.0 0.1 6.5e-12 46.0 0.0 2.7 3 1 0 3 3 3 1 Protein of unknown function (DUF563) AAA_13 PF13166.6 ORY39646.1 - 0.29 9.7 14.2 0.4 9.2 14.2 1.1 1 0 0 1 1 1 0 AAA domain DDHD PF02862.17 ORY39646.1 - 0.51 10.5 3.8 0.98 9.5 3.8 1.5 1 0 0 1 1 1 0 DDHD domain FAM76 PF16046.5 ORY39646.1 - 7.5 5.8 21.8 11 5.3 21.8 1.1 1 0 0 1 1 1 0 FAM76 protein FTR1 PF03239.14 ORY39647.1 - 1.4e-57 195.2 12.8 2.7e-34 118.8 4.7 2.0 1 1 1 2 2 2 2 Iron permease FTR1 family DUF2615 PF11027.8 ORY39647.1 - 0.14 12.3 0.1 5.3 7.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) DUF3180 PF11377.8 ORY39647.1 - 0.36 11.0 12.0 0.37 10.9 0.8 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) SID-1_RNA_chan PF13965.6 ORY39647.1 - 0.78 8.1 3.8 0.31 9.4 0.8 1.7 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF2207 PF09972.9 ORY39647.1 - 5.1 5.8 13.5 0.056 12.2 0.9 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) VEGFR-2_TMD PF17988.1 ORY39647.1 - 5.7 6.5 7.7 2.8 7.4 2.7 2.7 2 0 0 2 2 2 0 VEGFR-2 Transmembrane domain Phage_holin_3_6 PF07332.11 ORY39647.1 - 6.2 6.9 18.8 0.45 10.6 2.7 3.4 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4271 PF14093.6 ORY39647.1 - 8.6 6.2 14.3 0.71 9.8 2.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4271) DUF563 PF04577.14 ORY39648.1 - 4.4e-11 43.3 0.1 2.9e-10 40.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF563) DUF563 PF04577.14 ORY39649.1 - 1.4e-12 48.2 0.0 1.3e-11 45.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF563) DUF563 PF04577.14 ORY39651.1 - 1.2e-12 48.5 0.0 2.8e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF563) START PF01852.19 ORY39652.1 - 1.8e-14 53.7 0.0 2.8e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 START domain MOSP_C PF02722.15 ORY39652.1 - 0.092 12.4 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Major Outer Sheath Protein C-terminal domain FTR1 PF03239.14 ORY39654.1 - 6.8e-48 163.4 3.6 2.3e-26 92.7 0.1 2.1 2 0 0 2 2 2 2 Iron permease FTR1 family MgtE PF01769.16 ORY39654.1 - 0.16 12.4 12.5 0.96 9.8 4.0 2.3 2 0 0 2 2 2 0 Divalent cation transporter DUF3180 PF11377.8 ORY39654.1 - 0.41 10.8 9.2 0.079 13.1 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) Cytochrom_B561 PF03188.16 ORY39654.1 - 1.2 9.2 8.9 0.16 12.1 3.5 2.1 2 1 0 2 2 2 0 Eukaryotic cytochrome b561 FtsX PF02687.21 ORY39654.1 - 9.8 6.7 13.0 22 5.6 4.7 2.8 2 0 0 2 2 2 0 FtsX-like permease family FTR1 PF03239.14 ORY39655.1 - 3.5e-58 197.2 4.7 4.2e-36 124.7 0.5 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family FUN14 PF04930.15 ORY39655.1 - 1.4 9.4 0.0 1.4 9.4 0.0 3.0 4 0 0 4 4 4 0 FUN14 family DUF3180 PF11377.8 ORY39655.1 - 1.9 8.6 14.4 0.25 11.5 3.6 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3180) Cytochrom_B561 PF03188.16 ORY39655.1 - 5.3 7.2 12.7 0.053 13.7 3.4 2.4 3 0 0 3 3 3 0 Eukaryotic cytochrome b561 FTR1 PF03239.14 ORY39656.1 - 5.2e-58 196.6 0.9 1.6e-34 119.5 0.0 2.0 2 0 0 2 2 2 2 Iron permease FTR1 family DUF3180 PF11377.8 ORY39656.1 - 0.71 10.0 10.2 0.17 12.0 0.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) AAA_12 PF13087.6 ORY39657.1 - 1e-44 152.6 0.0 2.9e-44 151.1 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 ORY39657.1 - 4.5e-25 88.9 0.0 1.3e-15 57.9 0.0 2.5 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.6 ORY39657.1 - 1e-09 38.9 0.0 8.5e-09 35.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY39657.1 - 1.9e-09 37.5 0.0 2.4e-08 33.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 ORY39657.1 - 1.1e-05 25.6 0.0 2.8e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 ORY39657.1 - 0.00021 20.9 0.0 0.0092 15.5 0.0 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 ORY39657.1 - 0.002 18.0 0.0 0.0042 17.0 0.0 1.5 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.18 ORY39657.1 - 0.0054 16.5 0.0 1.3 8.7 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 ORY39657.1 - 0.019 14.9 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 ORY39657.1 - 0.019 15.3 0.0 0.044 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 ORY39657.1 - 0.067 13.0 0.1 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_23 PF13476.6 ORY39657.1 - 0.071 13.6 0.0 0.85 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 ORY39657.1 - 0.085 11.9 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 ORY39657.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PIF1 PF05970.14 ORY39657.1 - 0.13 11.4 0.0 1.5 7.9 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase FAD_binding_3 PF01494.19 ORY39658.1 - 7.2e-25 88.0 0.0 5.1e-15 55.6 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ORY39658.1 - 6.9e-13 48.5 0.7 5.4e-07 29.1 0.1 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY39658.1 - 1.8e-06 28.4 0.0 0.039 14.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY39658.1 - 3.9e-06 26.3 0.1 0.011 15.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY39658.1 - 5.2e-06 26.3 0.0 0.0031 17.1 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY39658.1 - 2.3e-05 23.3 0.1 0.0048 15.7 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Trp_halogenase PF04820.14 ORY39658.1 - 2.8e-05 23.1 0.2 0.068 12.0 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.6 ORY39658.1 - 4.2e-05 23.7 0.0 0.00013 22.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 ORY39658.1 - 0.0038 17.2 0.2 1.3 9.0 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.22 ORY39658.1 - 0.042 12.9 0.0 0.059 12.4 0.0 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A Amino_oxidase PF01593.24 ORY39658.1 - 0.044 13.1 0.0 0.12 11.6 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 ORY39658.1 - 0.082 11.9 0.0 0.5 9.4 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 ORY39658.1 - 0.085 11.9 0.0 0.3 10.1 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain DEAD PF00270.29 ORY39659.1 - 8.5e-21 74.5 0.0 2.2e-20 73.2 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY39659.1 - 1.6e-14 54.1 0.1 6.2e-14 52.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY39659.1 - 5.3e-08 33.1 0.0 1.1e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1998 PF09369.10 ORY39659.1 - 0.0028 18.4 0.3 0.0078 16.9 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) 7tm_3 PF00003.22 ORY39660.1 - 1.8e-12 47.5 18.9 2.7e-12 46.9 18.4 1.5 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 ORY39660.1 - 2.2e-05 23.7 0.0 3.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Phospholip_A2_3 PF09056.11 ORY39663.1 - 0.00019 22.1 4.1 0.00026 21.6 2.3 2.1 1 1 2 3 3 3 1 Prokaryotic phospholipase A2 PLA2G12 PF06951.11 ORY39663.1 - 0.0024 17.8 3.0 0.0034 17.3 3.0 1.3 1 0 0 1 1 1 1 Group XII secretory phospholipase A2 precursor (PLA2G12) DUF1353 PF07087.11 ORY39663.1 - 0.025 14.3 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) DNA_pol_E_B PF04042.16 ORY39664.1 - 6.8e-26 90.9 0.0 1.1e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 ORY39664.1 - 4e-10 40.1 5.5 2e-09 37.8 5.4 2.1 1 1 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal JHY PF15261.6 ORY39664.1 - 0.69 10.6 4.1 1.8 9.3 4.1 1.6 1 0 0 1 1 1 0 Jhy protein Herpes_DNAp_acc PF04929.12 ORY39664.1 - 1.4 7.8 6.9 45 2.9 6.2 2.5 2 0 0 2 2 2 0 Herpes DNA replication accessory factor cwf21 PF08312.12 ORY39665.1 - 6.9e-14 51.7 7.3 9.7e-14 51.3 7.3 1.2 1 0 0 1 1 1 1 cwf21 domain Transposase_24 PF03004.14 ORY39665.1 - 0.056 13.6 1.4 0.071 13.2 1.4 1.2 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) TauD PF02668.16 ORY39729.1 - 6.7e-51 173.6 0.4 9.8e-51 173.1 0.4 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF4962 PF16332.5 ORY39730.1 - 7.2e-16 57.7 1.9 1.3e-15 56.9 0.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4962) Hepar_II_III PF07940.13 ORY39730.1 - 2e-14 53.8 0.3 4.6e-07 29.7 0.1 2.3 2 0 0 2 2 2 2 Heparinase II/III-like protein TPR_12 PF13424.6 ORY39730.1 - 0.16 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat adh_short PF00106.25 ORY39809.1 - 2.3e-05 23.9 0.6 0.0046 16.4 0.6 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY39809.1 - 0.048 13.2 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase ACTL7A_N PF16840.5 ORY39810.1 - 0.028 14.5 0.1 0.034 14.2 0.1 1.2 1 0 0 1 1 1 0 Actin-like protein 7A N-terminus bZIP_1 PF00170.21 ORY39811.1 - 0.00033 20.7 6.8 0.00043 20.3 3.6 2.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORY39811.1 - 0.96 9.6 10.3 0.2 11.7 3.8 2.7 3 0 0 3 3 3 0 Basic region leucine zipper bZIP_1 PF00170.21 ORY39812.1 - 7.1e-07 29.2 9.9 4.7e-05 23.4 0.7 3.2 3 0 0 3 3 3 2 bZIP transcription factor bZIP_2 PF07716.15 ORY39812.1 - 0.56 10.3 13.0 0.11 12.6 2.6 3.1 3 0 0 3 3 3 0 Basic region leucine zipper PKcGMP_CC PF16808.5 ORY39812.1 - 0.82 9.6 6.6 21 5.1 0.1 3.3 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Ank_2 PF12796.7 ORY39813.1 - 2.2e-12 47.4 0.0 0.0097 16.5 0.0 4.3 2 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 ORY39813.1 - 0.00046 20.5 0.1 23 5.6 0.0 5.5 6 0 0 6 6 6 1 Ankyrin repeat F-box-like PF12937.7 ORY39813.1 - 0.068 13.1 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 F-box-like Heme_oxygenase PF01126.20 ORY39814.1 - 2e-49 168.2 0.0 2.3e-49 168.0 0.0 1.1 1 0 0 1 1 1 1 Heme oxygenase EF-hand_1 PF00036.32 ORY39815.1 - 1.6e-24 83.6 6.8 9.8e-06 24.8 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORY39815.1 - 4.9e-23 81.4 3.5 3.1e-11 43.6 0.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 ORY39815.1 - 2.7e-21 74.1 4.1 3.2e-05 23.2 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 ORY39815.1 - 1.4e-20 71.4 4.9 1.8e-05 24.3 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 ORY39815.1 - 5.6e-15 54.9 7.5 0.0015 18.3 0.2 4.3 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_11 PF08976.11 ORY39815.1 - 5.9e-05 23.9 0.0 0.01 16.7 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 ORY39815.1 - 0.0002 21.7 0.2 0.0022 18.3 0.1 2.2 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 ORY39815.1 - 0.025 14.8 1.5 0.12 12.6 0.1 2.8 3 1 0 3 3 3 0 Dockerin type I domain EF-hand_4 PF12763.7 ORY39815.1 - 0.06 13.3 2.5 15 5.6 0.1 3.3 2 2 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand DUF4756 PF15948.5 ORY39815.1 - 0.069 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4756) PMBR PF09373.10 ORY39815.1 - 0.17 12.1 0.0 1.1e+02 3.2 0.0 3.6 3 0 0 3 3 3 0 Pseudomurein-binding repeat bZIP_1 PF00170.21 ORY39816.1 - 0.0016 18.5 5.4 0.003 17.6 5.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF16 PF01519.16 ORY39816.1 - 0.043 14.3 0.4 0.086 13.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 NPV_P10 PF05531.12 ORY39816.1 - 0.55 10.7 4.2 0.44 11.0 0.2 2.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 ORY39816.1 - 0.72 9.7 4.0 1.4 8.8 4.0 1.5 1 0 0 1 1 1 0 Septum formation initiator Adaptin_binding PF10199.9 ORY39816.1 - 1.5 9.5 5.0 2.8 8.5 5.0 1.4 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 bZIP_1 PF00170.21 ORY39817.1 - 0.00088 19.3 8.2 0.0013 18.8 8.2 1.2 1 0 0 1 1 1 1 bZIP transcription factor Cauli_AT PF03233.13 ORY39817.1 - 0.041 13.8 0.5 0.061 13.2 0.5 1.2 1 0 0 1 1 1 0 Aphid transmission protein Mut7-C PF01927.16 ORY39817.1 - 0.069 13.3 1.4 0.12 12.5 1.4 1.4 1 0 0 1 1 1 0 Mut7-C RNAse domain HTH_WhiA PF02650.14 ORY39817.1 - 0.073 13.4 0.9 0.14 12.5 0.9 1.4 1 0 0 1 1 1 0 WhiA C-terminal HTH domain DUF4094 PF13334.6 ORY39817.1 - 0.074 13.5 1.2 0.14 12.6 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) zf-C2HE PF16278.5 ORY39817.1 - 0.13 12.7 0.2 0.29 11.6 0.2 1.7 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger BCL9 PF11502.8 ORY39817.1 - 0.37 10.6 4.0 0.71 9.7 4.0 1.5 1 0 0 1 1 1 0 B-cell lymphoma 9 protein UPF0242 PF06785.11 ORY39817.1 - 0.52 10.4 4.9 0.73 9.9 4.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_2 PF07716.15 ORY39817.1 - 1.6 8.9 9.1 2.5 8.3 8.6 1.6 1 1 1 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 ORY39818.1 - 6.7e-06 26.1 8.6 1.4e-05 25.1 8.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor Exonuc_VII_L PF02601.15 ORY39818.1 - 0.0049 16.5 0.7 0.0069 16.0 0.7 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit bZIP_2 PF07716.15 ORY39818.1 - 0.021 14.9 7.5 0.043 13.9 7.5 1.6 1 0 0 1 1 1 0 Basic region leucine zipper Mut7-C PF01927.16 ORY39818.1 - 0.03 14.4 0.6 0.066 13.3 0.6 1.5 1 0 0 1 1 1 0 Mut7-C RNAse domain DUF16 PF01519.16 ORY39818.1 - 0.032 14.7 1.1 0.061 13.8 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 CCDC92 PF14916.6 ORY39818.1 - 0.05 13.4 1.8 0.17 11.6 1.8 1.8 1 1 0 1 1 1 0 Coiled-coil domain of unknown function ABC_tran_Xtn PF12848.7 ORY39818.1 - 2.5 8.2 6.0 4.8 7.3 6.0 1.4 1 0 0 1 1 1 0 ABC transporter bZIP_1 PF00170.21 ORY39819.1 - 0.018 15.1 8.8 0.018 15.1 8.8 2.0 2 0 0 2 2 2 0 bZIP transcription factor bZIP_Maf PF03131.17 ORY39819.1 - 0.21 12.1 9.2 0.071 13.6 6.1 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor FliD_N PF02465.18 ORY39819.1 - 0.26 12.0 1.3 0.3 11.8 0.1 1.8 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus PRKG1_interact PF15898.5 ORY39819.1 - 0.73 10.8 9.9 1.3 10.0 9.3 1.7 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain bZIP_2 PF07716.15 ORY39819.1 - 6.1 7.0 16.4 2.7 8.2 13.1 2.2 2 1 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 ORY39821.1 - 3e-05 24.0 6.8 5.2e-05 23.3 6.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY39821.1 - 0.032 14.3 4.3 0.056 13.5 4.3 1.4 1 0 0 1 1 1 0 Basic region leucine zipper AKAP2_C PF15304.6 ORY39821.1 - 0.07 12.4 5.1 0.1 11.9 4.2 1.6 1 1 0 1 1 1 0 A-kinase anchor protein 2 C-terminus CTU2 PF10288.9 ORY39821.1 - 0.33 11.2 3.4 0.31 11.3 2.0 1.7 1 1 1 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 NUDE_C PF04880.13 ORY39821.1 - 2.1 8.8 12.0 4.9 7.6 11.9 1.7 1 1 0 1 1 1 0 NUDE protein, C-terminal conserved region Peptidase_S8 PF00082.22 ORY39823.1 - 1.1e-66 225.1 0.8 1.7e-66 224.5 0.8 1.2 1 0 0 1 1 1 1 Subtilase family TPPII PF12580.8 ORY39823.1 - 3.6e-46 157.0 0.0 5.8e-46 156.4 0.0 1.3 1 0 0 1 1 1 1 Tripeptidyl peptidase II EF-hand_2 PF09068.11 ORY39823.1 - 0.18 11.9 0.0 0.58 10.3 0.0 1.8 1 0 0 1 1 1 0 EF hand p450 PF00067.22 ORY39827.1 - 3.2e-41 141.6 0.0 8.9e-41 140.1 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 LRR_9 PF14580.6 ORY39828.1 - 1.1e-58 197.7 40.0 4.8e-19 68.5 2.4 8.2 3 2 4 7 7 7 7 Leucine-rich repeat LRR_4 PF12799.7 ORY39828.1 - 6.4e-53 175.8 92.2 1.5e-08 34.8 3.4 16.7 9 4 10 21 21 21 17 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY39828.1 - 1.3e-48 162.5 76.7 6.3e-13 48.3 4.7 12.2 7 3 5 13 13 13 11 Leucine rich repeat LRR_6 PF13516.6 ORY39828.1 - 0.00067 19.5 56.1 1.1 9.5 0.2 16.5 18 1 1 19 19 19 4 Leucine Rich repeat RecC_C PF17946.1 ORY39828.1 - 0.081 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 RecC C-terminal domain DUF3744 PF12558.8 ORY39828.1 - 0.11 13.2 0.5 10 7.0 0.0 4.2 3 0 0 3 3 3 0 ATP-binding cassette cobalt transporter LRR_5 PF13306.6 ORY39828.1 - 0.97 9.4 22.1 0.19 11.7 1.3 6.0 5 1 0 5 5 5 0 BspA type Leucine rich repeat region (6 copies) STAS PF01740.21 ORY39829.1 - 0.18 11.4 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 STAS domain LRR_8 PF13855.6 ORY39830.1 - 0.00056 19.6 0.8 0.0037 17.0 0.6 2.4 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 ORY39830.1 - 0.0013 19.1 1.5 1.7 9.1 0.1 2.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY39830.1 - 0.091 12.9 1.2 18 5.7 0.1 3.0 2 0 0 2 2 2 0 Leucine Rich repeat LRR_1 PF00560.33 ORY39830.1 - 0.25 12.0 3.2 6.2 7.8 0.8 3.3 2 1 0 2 2 2 0 Leucine Rich Repeat Mod_r PF07200.13 ORY39835.1 - 2.8e-19 69.7 1.3 3.1e-19 69.5 1.3 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Wtap PF17098.5 ORY39835.1 - 0.045 13.7 0.4 0.056 13.4 0.4 1.3 1 0 0 1 1 1 0 WTAP/Mum2p family AhpC-TSA PF00578.21 ORY39836.1 - 3.9e-25 88.2 0.0 6e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY39836.1 - 2.1e-18 66.5 0.0 3.1e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Redoxin NOA36 PF06524.12 ORY39836.1 - 0.058 12.7 3.4 0.087 12.1 3.4 1.3 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 ORY39836.1 - 0.077 13.4 8.5 0.15 12.4 8.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Presenilin PF01080.17 ORY39836.1 - 0.11 11.3 5.2 0.15 10.8 5.2 1.1 1 0 0 1 1 1 0 Presenilin FAM176 PF14851.6 ORY39836.1 - 0.32 10.7 4.0 0.51 10.0 4.0 1.4 1 0 0 1 1 1 0 FAM176 family Spore_coat_CotO PF14153.6 ORY39836.1 - 0.32 10.9 5.7 0.49 10.3 5.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Zip PF02535.22 ORY39836.1 - 0.43 9.8 2.3 0.46 9.6 2.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter ORC6 PF05460.13 ORY39836.1 - 0.53 9.5 10.5 0.78 9.0 10.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Med13_C PF06333.12 ORY39836.1 - 0.57 9.4 8.2 0.92 8.7 8.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Tim54 PF11711.8 ORY39836.1 - 1.3 7.7 6.8 1.9 7.2 6.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CT47 PF15623.6 ORY39836.1 - 2.9 7.6 9.2 4.5 7.0 9.2 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 SAPS PF04499.15 ORY39836.1 - 3 6.5 7.1 3.8 6.2 7.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nucleo_P87 PF07267.11 ORY39836.1 - 4 6.2 8.4 5.2 5.8 8.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RR_TM4-6 PF06459.12 ORY39836.1 - 6.1 6.6 8.5 8.2 6.2 8.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Mit_KHE1 PF10173.9 ORY39838.1 - 2e-08 34.5 0.1 4e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related PTCB-BRCT PF12738.7 ORY39842.1 - 7.9e-67 221.1 4.5 2.6e-17 62.5 0.0 5.6 5 0 0 5 5 5 5 twin BRCT domain BRCT PF00533.26 ORY39842.1 - 4e-50 168.1 6.1 1.2e-12 48.1 0.0 7.1 8 0 0 8 8 8 6 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 ORY39842.1 - 1.3e-32 112.0 0.0 3.2e-05 24.2 0.0 6.6 6 0 0 6 6 6 6 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 ORY39842.1 - 1.9e-16 60.1 0.1 0.19 12.0 0.0 6.3 6 0 0 6 6 6 5 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 ORY39842.1 - 2e-13 50.1 0.0 3.6e-06 26.8 0.0 4.8 4 1 1 5 5 5 2 Regulator of Ty1 transposition protein 107 BRCT domain Serglycin PF04360.12 ORY39842.1 - 0.013 15.4 0.5 0.03 14.3 0.5 1.5 1 0 0 1 1 1 0 Serglycin BBE PF08031.12 ORY39842.1 - 0.16 12.1 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 Berberine and berberine like Ndc1_Nup PF09531.10 ORY39842.1 - 2.3 6.8 15.6 0.47 9.1 0.0 2.6 3 0 0 3 3 3 0 Nucleoporin protein Ndc1-Nup KIX_2 PF16987.5 ORY39843.1 - 0.011 15.8 1.0 0.011 15.7 1.0 1.1 1 0 0 1 1 1 0 KIX domain KIX_2 PF16987.5 ORY39845.1 - 5.1e-06 26.4 0.2 1.1e-05 25.3 0.0 1.6 2 0 0 2 2 2 1 KIX domain F-box-like PF12937.7 ORY39846.1 - 0.00016 21.5 0.1 0.00034 20.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like DUF4827 PF16109.5 ORY39847.1 - 0.031 14.3 1.0 0.052 13.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4827) DicB PF05358.11 ORY39847.1 - 0.14 12.3 0.0 5.4 7.3 0.0 2.6 2 0 0 2 2 2 0 DicB protein Mucin PF01456.17 ORY39847.1 - 0.52 10.3 26.3 1.3 9.0 26.3 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Hydantoinase_B PF02538.14 ORY39848.1 - 0.0036 15.8 0.3 0.0078 14.7 0.3 1.5 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase DUF846 PF05832.12 ORY39849.1 - 1.6e-53 180.5 15.6 1.9e-53 180.2 15.6 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Phage_holin_3_6 PF07332.11 ORY39849.1 - 7.9 6.6 9.1 9.1 6.4 0.8 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III STAS PF01740.21 ORY39850.1 - 6.2e-06 25.8 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 ORY39850.1 - 0.025 14.9 0.0 0.05 13.9 0.0 1.5 1 0 0 1 1 1 0 STAS domain ORC3_N PF07034.11 ORY39852.1 - 2.9e-26 92.4 6.1 3.5e-26 92.1 2.8 2.5 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 ORY39852.1 - 9.1e-22 77.6 0.2 5e-11 42.8 0.0 3.0 2 1 1 3 3 3 2 Origin recognition complex winged helix C-terminal Gpi1 PF05024.15 ORY39852.1 - 0.065 13.3 0.1 0.52 10.4 0.1 2.3 2 0 0 2 2 2 0 N-acetylglucosaminyl transferase component (Gpi1) Cep57_MT_bd PF06657.13 ORY39854.1 - 0.015 15.8 5.5 9.4 6.8 0.0 4.3 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 MNE1 PF13762.6 ORY39854.1 - 0.091 12.7 4.5 0.2 11.6 4.5 1.5 1 0 0 1 1 1 0 Mitochondrial splicing apparatus component RICH PF05062.12 ORY39854.1 - 0.18 12.2 2.0 0.51 10.7 0.5 2.2 2 0 0 2 2 2 0 RICH domain AA_permease_2 PF13520.6 ORY39859.1 - 5.3e-51 173.8 54.7 6.6e-51 173.5 54.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY39859.1 - 1.4e-22 80.0 50.1 1.8e-22 79.6 50.1 1.0 1 0 0 1 1 1 1 Amino acid permease Pox_L3_FP4 PF03339.14 ORY39859.1 - 0.042 12.8 0.1 0.067 12.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus L3/FP4 protein MFS_1 PF07690.16 ORY39860.1 - 4.2e-10 39.1 28.7 7.4e-10 38.3 28.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY39860.1 - 0.054 13.2 16.7 0.17 11.6 2.4 3.4 4 1 0 4 4 4 0 Ion channel regulatory protein UNC-93 UL41A PF17591.2 ORY39860.1 - 0.1 12.7 0.1 0.57 10.3 0.1 2.3 1 0 0 1 1 1 0 Herpesvirus UL41A Fasciclin PF02469.22 ORY39861.1 - 2.8e-36 124.6 6.4 2.6e-21 76.2 2.1 2.1 2 0 0 2 2 2 2 Fasciclin domain LSM PF01423.22 ORY39862.1 - 5.4e-16 58.0 0.2 6.8e-16 57.7 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORY39862.1 - 0.00014 21.9 0.0 0.00017 21.6 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF1461 PF07314.11 ORY39862.1 - 0.088 12.7 0.0 0.1 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) DUF2642 PF10842.8 ORY39862.1 - 0.1 12.5 0.1 0.2 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) Tctex-1 PF03645.13 ORY39863.1 - 4.5e-28 97.5 0.0 5.1e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family RasGEF PF00617.19 ORY39864.1 - 2.3e-53 181.0 0.9 4.6e-53 180.0 0.1 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 ORY39864.1 - 1.5e-19 70.2 0.0 4e-19 68.8 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif RBD PF02196.15 ORY39864.1 - 3.4e-10 39.8 0.0 0.00015 21.8 0.0 3.0 2 0 0 2 2 2 2 Raf-like Ras-binding domain TUG-UBL1 PF11470.8 ORY39864.1 - 4.3e-05 23.6 0.0 0.083 13.1 0.0 2.7 2 0 0 2 2 2 2 TUG ubiquitin-like domain Alpha_adaptinC2 PF02883.20 ORY39864.1 - 0.037 14.3 0.1 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 Adaptin C-terminal domain HSBP1 PF06825.12 ORY39866.1 - 0.035 14.0 0.2 0.22 11.4 0.2 2.1 2 0 0 2 2 2 0 Heat shock factor binding protein 1 HA2 PF04408.23 ORY39867.1 - 7.6e-20 71.2 0.0 1.6e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 ORY39867.1 - 4.8e-16 58.9 0.0 1.5e-15 57.3 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 ORY39867.1 - 7.1e-13 48.9 0.0 3.2e-12 46.8 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY39867.1 - 1.6e-06 28.0 0.2 1.2e-05 25.1 0.1 2.4 2 1 1 3 3 3 1 DEAD/DEAH box helicase AAA_30 PF13604.6 ORY39867.1 - 0.00018 21.3 0.0 0.00034 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY39867.1 - 0.0011 19.2 0.1 0.0041 17.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY39867.1 - 0.0053 17.1 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 ORY39867.1 - 0.0068 16.4 0.7 11 6.0 0.0 3.2 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit cobW PF02492.19 ORY39867.1 - 0.051 13.2 0.2 1.9 8.0 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 ORY39867.1 - 0.06 13.9 0.0 0.19 12.3 0.0 1.8 1 1 0 1 1 1 0 ABC transporter SRP54 PF00448.22 ORY39867.1 - 0.065 12.9 0.5 0.2 11.3 0.1 2.1 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain SCO1-SenC PF02630.14 ORY39867.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 SCO1/SenC T2SSE PF00437.20 ORY39867.1 - 0.13 11.3 0.0 0.3 10.1 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Metallophos PF00149.28 ORY39868.1 - 4.9e-36 125.2 0.1 7.9e-36 124.5 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 ORY39868.1 - 0.057 12.7 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5378) LRR_8 PF13855.6 ORY39869.1 - 6.6e-10 38.6 0.5 0.00025 20.7 0.2 2.7 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY39869.1 - 1.2e-08 35.1 1.6 0.00085 19.7 0.1 4.0 1 1 5 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY39869.1 - 3e-05 23.9 7.3 13 6.9 0.0 6.7 6 1 0 6 6 6 2 Leucine Rich Repeat F-box PF00646.33 ORY39869.1 - 4.2e-05 23.3 2.5 0.00016 21.5 2.5 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY39869.1 - 0.00066 19.5 3.3 0.00079 19.3 1.7 2.0 2 0 0 2 2 2 1 F-box-like DUF3429 PF11911.8 ORY39869.1 - 0.19 12.0 0.0 0.31 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) UCH PF00443.29 ORY39870.1 - 2.8e-39 135.2 0.0 3.4e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 ORY39870.1 - 1.1e-13 51.2 0.3 2.8e-13 50.0 0.3 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 ORY39870.1 - 1e-07 31.9 0.0 3.3e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase F5_F8_type_C PF00754.25 ORY39871.1 - 0.0023 18.0 0.9 0.0061 16.7 0.9 1.7 1 0 0 1 1 1 1 F5/8 type C domain Sod_Fe_C PF02777.18 ORY39872.1 - 2.6e-37 127.1 0.4 5.2e-37 126.1 0.4 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 ORY39872.1 - 2.7e-27 95.1 0.3 4.7e-27 94.3 0.3 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Pro_isomerase PF00160.21 ORY39873.1 - 2.1e-30 106.1 0.0 3.1e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 ORY39873.1 - 2.5e-16 59.3 0.1 6.2e-16 58.0 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CHCH PF06747.13 ORY39874.1 - 3.6e-07 30.1 3.9 4.5e-07 29.8 3.9 1.1 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.9 ORY39874.1 - 0.0084 16.2 0.6 0.01 15.9 0.6 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CX9C PF16860.5 ORY39874.1 - 0.022 14.8 1.7 0.03 14.3 1.7 1.1 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, SeqA_N PF17206.3 ORY39875.1 - 0.14 11.5 0.1 0.71 9.2 0.0 2.0 2 0 0 2 2 2 0 SeqA protein N-terminal domain Mito_carr PF00153.27 ORY39876.1 - 3.1e-69 229.0 1.6 1.5e-24 85.7 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein CTK3_C PF12350.8 ORY39877.1 - 3.3e-10 40.0 2.9 6.5e-10 39.0 2.9 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CTK3 PF12243.8 ORY39877.1 - 2.3e-07 30.9 0.0 3.2e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTD_bind PF04818.13 ORY39877.1 - 7.6e-07 29.9 0.1 1.3e-06 29.1 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase II-binding domain. NMD3 PF04981.13 ORY39877.1 - 0.013 15.0 0.1 0.016 14.7 0.1 1.2 1 0 0 1 1 1 0 NMD3 family JAMP PF05571.12 ORY39877.1 - 0.18 11.4 0.0 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein BRE1 PF08647.11 ORY39878.1 - 3.2e-15 56.0 13.2 3.2e-15 56.0 13.2 7.1 5 2 2 7 7 6 2 BRE1 E3 ubiquitin ligase zf-C3HC4 PF00097.25 ORY39878.1 - 1.7e-07 31.0 13.2 3.1e-07 30.1 13.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY39878.1 - 2.7e-07 30.3 8.5 4.6e-07 29.6 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY39878.1 - 2.6e-06 27.3 11.8 4.6e-06 26.5 11.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY39878.1 - 5.7e-05 22.9 9.3 9.5e-05 22.2 9.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 ORY39878.1 - 6.2e-05 23.3 10.1 0.00012 22.3 10.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY39878.1 - 7.6e-05 22.5 11.9 0.00014 21.6 11.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY39878.1 - 0.00013 21.9 8.2 0.00026 20.9 8.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger TPR_MLP1_2 PF07926.12 ORY39878.1 - 0.00038 20.5 5.1 0.00038 20.5 5.1 7.1 5 3 2 7 7 7 2 TPR/MLP1/MLP2-like protein zf-rbx1 PF12678.7 ORY39878.1 - 0.033 14.5 6.3 0.082 13.2 6.3 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 ORY39878.1 - 0.041 13.7 6.3 0.077 12.8 6.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 ORY39878.1 - 0.042 13.7 4.6 0.11 12.4 4.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF3800 PF12686.7 ORY39878.1 - 0.043 14.5 1.0 18 6.0 1.0 3.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) zf-C3HC4_5 PF17121.5 ORY39878.1 - 0.045 13.6 4.8 0.11 12.4 4.8 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.11 ORY39878.1 - 0.046 13.8 4.8 0.1 12.7 4.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.6 ORY39878.1 - 0.047 13.8 9.4 0.088 13.0 9.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING GIT_CC PF16559.5 ORY39878.1 - 0.066 13.1 0.2 0.066 13.1 0.2 7.2 7 1 0 7 7 7 0 GIT coiled-coil Rho guanine nucleotide exchange factor Ntox16 PF15523.6 ORY39878.1 - 0.19 12.0 0.1 0.19 12.0 0.1 3.9 3 1 2 5 5 4 0 Novel toxin 16 DUF1382 PF07131.11 ORY39878.1 - 0.62 10.1 5.7 10 6.2 0.6 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1382) zf-Nse PF11789.8 ORY39878.1 - 0.75 9.7 3.9 2.3 8.1 3.9 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DZR PF12773.7 ORY39878.1 - 0.81 9.8 7.2 1.8 8.6 7.2 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-C2HC_2 PF13913.6 ORY39878.1 - 1.5 8.8 4.5 24 5.0 0.1 2.7 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF3987 PF13148.6 ORY39879.1 - 5e-15 55.4 0.0 1.1e-06 27.9 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF3987) NDC10_II PF16787.5 ORY39883.1 - 0.026 13.6 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 ORY39883.1 - 0.06 13.7 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes NDC10_II PF16787.5 ORY39884.1 - 6.3e-05 22.2 0.0 0.00011 21.3 0.0 1.5 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Cytochrom_B558a PF05038.13 ORY39884.1 - 1.4 8.4 3.0 2.7 7.5 3.0 1.4 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit DDE_Tnp_4 PF13359.6 ORY39888.1 - 1.4e-11 44.3 0.0 3.7e-11 42.9 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 ORY39888.1 - 7.4e-06 25.8 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain Peptidase_S49_N PF08496.10 ORY39889.1 - 0.36 10.9 6.6 0.22 11.6 4.1 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CDC27 PF09507.10 ORY39889.1 - 0.72 9.2 25.0 0.29 10.5 18.4 2.0 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 RXT2_N PF08595.11 ORY39889.1 - 3.4 7.7 15.7 2.9 7.9 12.0 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal NOA36 PF06524.12 ORY39889.1 - 3.8 6.7 18.6 8.2 5.6 18.6 1.6 1 0 0 1 1 1 0 NOA36 protein UPF0524 PF15823.5 ORY39889.1 - 4.4 6.6 8.4 7.3 5.9 8.4 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 DDE_Tnp_4 PF13359.6 ORY39890.1 - 0.0046 16.6 0.0 0.0058 16.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Methyltransf_11 PF08241.12 ORY39892.1 - 3.4e-14 53.2 0.0 6.4e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY39892.1 - 3.2e-13 49.9 0.0 6.8e-13 48.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY39892.1 - 3.8e-13 49.9 0.0 6.6e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY39892.1 - 2.9e-11 44.0 0.0 4.9e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY39892.1 - 2.3e-08 34.0 0.0 3.5e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 ORY39892.1 - 4.5e-05 22.5 0.0 8.7e-05 21.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 ORY39892.1 - 8e-05 22.2 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 ORY39892.1 - 0.00025 20.6 0.0 0.00034 20.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 ORY39892.1 - 0.00084 18.7 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DREV PF05219.12 ORY39892.1 - 0.0059 15.7 0.0 0.0092 15.1 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase PCMT PF01135.19 ORY39892.1 - 0.0085 15.9 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.20 ORY39892.1 - 0.081 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.18 ORY39892.1 - 0.099 12.0 0.0 0.32 10.3 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 ORY39892.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 ORY39892.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Tho1_MOS11_C PF18592.1 ORY39893.1 - 1.1e-11 44.3 10.6 2.8e-05 23.8 1.9 4.7 3 1 2 5 5 5 3 Tho1/MOS11 C-terminal domain SAP PF02037.27 ORY39893.1 - 1.5e-11 43.7 1.2 3.6e-11 42.6 0.3 2.2 2 0 0 2 2 2 1 SAP domain HTH_Tnp_IS630 PF01710.16 ORY39893.1 - 0.018 15.1 0.2 5.7 7.0 0.1 2.7 2 1 0 2 2 2 0 Transposase Med26 PF08711.11 ORY39894.1 - 2.7e-05 24.1 0.1 8.3e-05 22.5 0.1 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain PHC2_SAM_assoc PF16616.5 ORY39894.1 - 0.12 13.2 9.8 0.21 12.4 1.1 2.4 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 SURF6 PF04935.12 ORY39894.1 - 0.13 12.0 3.5 2.6 7.8 1.4 2.3 2 0 0 2 2 2 0 Surfeit locus protein 6 DUF572 PF04502.13 ORY39894.1 - 5.2 6.6 7.5 0.16 11.6 1.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF572) zf_CCCH_4 PF18345.1 ORY39895.1 - 0.00024 21.1 7.9 0.00037 20.5 7.9 1.3 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 ORY39895.1 - 0.015 15.2 5.8 0.027 14.4 5.8 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 ORY39895.1 - 0.023 15.4 4.5 0.066 13.9 4.5 1.8 1 1 0 1 1 1 0 Torus domain zf-CCCH_4 PF18044.1 ORY39895.1 - 0.031 14.1 5.2 0.047 13.5 5.2 1.3 1 0 0 1 1 1 0 CCCH-type zinc finger TFIIA PF03153.13 ORY39895.1 - 2.4 8.1 33.3 3.5 7.5 33.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MCM PF00493.23 ORY39896.1 - 1e-104 348.5 0.1 1.5e-104 348.0 0.1 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY39896.1 - 1.6e-36 124.9 0.8 2.5e-36 124.3 0.2 1.7 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 ORY39896.1 - 1.3e-24 86.4 0.3 3e-24 85.2 0.3 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM6_C PF18263.1 ORY39896.1 - 7.1e-20 71.3 0.0 1.9e-19 69.9 0.0 1.8 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_N PF14551.6 ORY39896.1 - 1.8e-10 41.3 0.0 5.9e-10 39.7 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ORY39896.1 - 2.9e-07 30.1 0.0 5.9e-06 25.8 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 ORY39896.1 - 0.00011 22.1 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY39896.1 - 0.00016 21.7 0.0 0.00035 20.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 ORY39896.1 - 0.0047 16.7 0.0 0.0097 15.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Phage_XkdX PF09693.10 ORY39896.1 - 0.11 12.6 0.0 0.35 10.9 0.0 1.9 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) Polyoma_coat2 PF00761.20 ORY39896.1 - 0.46 10.1 3.4 0.13 12.0 0.3 1.6 2 0 0 2 2 2 0 Polyomavirus coat protein ASH PF15780.5 ORY39900.1 - 3.6e-06 27.1 0.4 0.42 10.9 0.0 4.6 4 0 0 4 4 4 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Phage_term_sma PF07141.11 ORY39900.1 - 0.043 13.6 0.1 0.097 12.4 0.1 1.5 1 0 0 1 1 1 0 Putative bacteriophage terminase small subunit Bul1_C PF04426.12 ORY39900.1 - 5.6 6.3 8.9 0.19 11.1 0.9 2.1 2 0 0 2 2 2 0 Bul1 C terminus ASH PF15780.5 ORY39901.1 - 5.3e-09 36.2 0.2 0.00013 22.1 0.1 2.8 2 0 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 ORY39901.1 - 7.8e-07 29.3 0.9 0.0023 18.1 0.1 3.4 3 0 0 3 3 3 1 Transmembrane protein 131-like PapD-like PF14874.6 ORY39901.1 - 1.3e-05 25.3 0.0 0.0015 18.7 0.0 3.1 4 0 0 4 4 4 1 Flagellar-associated PapD-like IL17R_fnIII_D1 PF16556.5 ORY39901.1 - 0.0012 18.5 0.0 0.0056 16.3 0.0 2.0 3 0 0 3 3 3 1 Interleukin-17 receptor, fibronectin-III-like domain 1 Motile_Sperm PF00635.26 ORY39901.1 - 0.0016 18.3 0.1 2.3 8.1 0.0 2.9 3 0 0 3 3 3 2 MSP (Major sperm protein) domain FixG_C PF11614.8 ORY39901.1 - 0.0059 16.8 0.1 0.026 14.7 0.1 2.0 2 0 0 2 2 2 1 IG-like fold at C-terminal of FixG, putative oxidoreductase Transglut_C PF00927.22 ORY39901.1 - 0.041 14.0 0.2 0.42 10.8 0.1 2.6 3 0 0 3 3 3 0 Transglutaminase family, C-terminal ig like domain fn3_5 PF06280.12 ORY39901.1 - 0.073 13.8 0.1 20 5.9 0.0 2.6 2 0 0 2 2 2 0 Fn3-like domain Glyco_hydro_30C PF17189.4 ORY39901.1 - 0.074 13.3 0.4 1.5 9.1 0.1 2.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 30 beta sandwich domain TFIIA_gamma_N PF02268.16 ORY39902.1 - 4e-21 74.8 0.0 6.6e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 ORY39902.1 - 1.3e-16 60.4 1.0 2e-16 59.9 1.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit cNMP_binding PF00027.29 ORY39904.1 - 2.2e-19 69.3 0.0 3.9e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF2441 PF10386.9 ORY39904.1 - 0.066 13.2 0.2 0.19 11.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2441) GAT PF03127.14 ORY39905.1 - 5.6e-09 36.2 0.0 1.4e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 GAT domain LRR_6 PF13516.6 ORY39905.1 - 4.4e-05 23.2 7.9 0.018 15.1 0.4 4.5 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 ORY39905.1 - 2.6 8.9 4.3 2.6e+02 2.8 0.1 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat PRIMA1 PF16101.5 ORY39907.1 - 0.13 12.3 0.8 0.17 11.9 0.7 1.3 1 1 0 1 1 1 0 Proline-rich membrane anchor 1 F-box-like PF12937.7 ORY39908.1 - 3e-09 36.6 0.0 5.8e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY39908.1 - 1.8e-07 30.8 0.0 4.5e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ORY39908.1 - 0.0015 18.4 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 F-box NDUFA12 PF05071.16 ORY39909.1 - 1.4e-07 32.3 2.0 4.9e-07 30.5 2.0 1.8 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 DUF3584 PF12128.8 ORY39910.1 - 0.00033 18.4 2.6 0.00046 17.9 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Apolipoprotein PF01442.18 ORY39910.1 - 0.0019 18.1 2.5 0.0029 17.5 2.5 1.3 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain TPR_MLP1_2 PF07926.12 ORY39910.1 - 0.01 15.9 1.9 0.021 14.9 1.9 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein IZUMO PF15005.6 ORY39910.1 - 0.015 15.8 1.4 0.025 15.1 1.4 1.4 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated TetR_C_32 PF09209.11 ORY39910.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Phage_int_SAM_1 PF02899.17 ORY39910.1 - 0.043 14.1 0.4 0.6 10.5 0.1 2.4 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain CLZ PF16526.5 ORY39910.1 - 0.53 10.7 4.0 0.73 10.2 1.5 2.6 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels zf-C2H2 PF00096.26 ORY39912.1 - 1.6e-10 40.9 17.8 0.0011 19.4 2.2 3.7 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY39912.1 - 8.7e-09 35.5 20.4 0.0036 18.0 0.4 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY39912.1 - 2e-05 24.8 6.4 0.023 15.1 0.0 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY39912.1 - 7.2e-05 23.0 4.0 0.24 11.7 0.5 3.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 ORY39912.1 - 0.00017 22.3 2.3 0.0056 17.4 1.1 2.3 2 0 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 ORY39912.1 - 0.0019 18.2 11.9 0.012 15.6 0.1 3.7 3 0 0 3 3 3 1 C2H2-type zinc finger FOXP-CC PF16159.5 ORY39912.1 - 0.0047 17.5 5.6 0.0047 17.5 5.6 2.1 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORY39912.1 - 0.0093 16.2 3.0 0.0093 16.2 3.0 2.0 1 1 1 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 ORY39912.1 - 0.04 13.7 1.4 0.04 13.7 1.4 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-met PF12874.7 ORY39912.1 - 0.61 10.6 13.8 5.7 7.5 2.8 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-AN1 PF01428.16 ORY39912.1 - 0.91 9.7 6.3 13 6.1 1.9 3.0 1 1 1 2 2 2 0 AN1-like Zinc finger zf-C2H2_4 PF13894.6 ORY39913.1 - 0.00012 22.6 8.9 0.0017 19.0 0.2 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger Zn-C2H2_12 PF18112.1 ORY39913.1 - 0.0024 18.3 0.3 0.0063 17.0 0.3 1.8 1 0 0 1 1 1 1 Autophagy receptor zinc finger-C2H2 domain zf-C2H2_9 PF16293.5 ORY39913.1 - 0.0031 17.3 0.8 0.93 9.4 0.1 3.0 2 0 0 2 2 2 2 C2H2 type zinc-finger (1 copy) zf-C2H2_2 PF12756.7 ORY39913.1 - 0.072 13.4 2.0 0.2 12.0 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 ORY39913.1 - 0.41 11.2 11.7 0.68 10.5 0.1 3.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 ORY39913.1 - 0.47 10.8 2.6 1 9.7 0.0 2.8 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 ORY39913.1 - 1.7 8.8 5.4 0.27 11.3 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger DUF667 PF05018.13 ORY39914.1 - 1.1e-22 80.7 0.0 1.7e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF667) Glyco_hydro_18 PF00704.28 ORY39915.1 - 5.3e-09 36.2 0.0 6.4e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PDEase_I PF00233.19 ORY39916.1 - 1.3e-80 270.5 0.0 2e-80 269.9 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PCI PF01399.27 ORY39917.1 - 0.0034 17.9 0.0 0.0084 16.6 0.0 1.7 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 ORY39917.1 - 1.5 9.2 2.9 1.4 9.2 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Solute_trans_a PF03619.16 ORY39918.1 - 1.6e-25 90.1 2.6 2.3e-25 89.7 2.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha SAM_2 PF07647.17 ORY39919.1 - 0.00046 20.2 0.0 0.0006 19.9 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Arrestin_N PF00339.29 ORY39920.1 - 2.2e-06 27.8 0.0 5e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain SAM_2 PF07647.17 ORY39920.1 - 0.011 15.8 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORY39920.1 - 0.069 13.6 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Arrestin_N PF00339.29 ORY39921.1 - 0.0003 20.9 0.1 0.00053 20.1 0.1 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY39921.1 - 0.00036 21.0 0.7 0.52 10.8 0.3 2.7 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain SAM_2 PF07647.17 ORY39922.1 - 4.8e-13 49.0 0.0 9.5e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORY39922.1 - 9.7e-13 48.4 0.1 1.5e-12 47.7 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 ORY39922.1 - 0.0072 16.5 0.1 0.011 15.9 0.1 1.3 1 0 0 1 1 1 1 Ste50p, sterile alpha motif SAM_PNT PF02198.16 ORY39922.1 - 0.018 15.0 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DNA_pol_A_exo1 PF01612.20 ORY39923.1 - 3.8e-12 46.3 0.0 7e-11 42.2 0.0 2.3 2 0 0 2 2 2 1 3'-5' exonuclease OTU PF02338.19 ORY39923.1 - 5.4e-06 26.9 0.1 1.1e-05 26.0 0.1 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Arrestin_N PF00339.29 ORY39924.1 - 0.1 12.6 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Hydrolase_4 PF12146.8 ORY39925.1 - 1.8e-08 33.9 0.0 2.1e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY39925.1 - 4.3e-07 30.8 0.1 5.2e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY39925.1 - 5.4e-06 26.2 0.0 7.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 ORY39925.1 - 0.00046 20.4 0.0 0.00063 19.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 ORY39925.1 - 0.036 13.9 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_M48 PF01435.18 ORY39927.1 - 7.7e-14 51.9 0.0 2.4e-11 43.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M48 Syja_N PF02383.18 ORY39929.1 - 4e-50 171.0 2.4 1.5e-34 119.8 2.6 3.3 1 1 1 2 2 2 2 SacI homology domain MIF4G PF02854.19 ORY39930.1 - 6e-49 166.6 7.0 1.6e-31 109.6 0.3 3.6 3 1 0 3 3 3 2 MIF4G domain Upf2 PF04050.14 ORY39930.1 - 2.3e-25 89.9 8.1 6.7e-25 88.4 8.1 1.8 1 0 0 1 1 1 1 Up-frameshift suppressor 2 Pkinase PF00069.25 ORY39933.1 - 0.00024 20.5 0.0 0.00045 19.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain zf-CCCH_2 PF14608.6 ORY39933.1 - 0.0016 18.9 5.9 0.76 10.4 1.0 2.8 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 ORY39933.1 - 0.021 14.9 7.2 0.05 13.7 1.1 2.5 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 ORY39933.1 - 0.044 13.7 0.4 0.044 13.7 0.4 2.1 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) FlaC_arch PF05377.11 ORY39934.1 - 0.002 18.5 0.4 0.02 15.3 0.3 2.4 2 1 1 3 3 3 1 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.22 ORY39934.1 - 0.015 15.5 2.9 0.022 15.0 2.8 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Vac_Fusion PF02346.16 ORY39934.1 - 0.019 14.6 0.3 0.049 13.3 0.3 1.8 1 1 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 GAS PF13851.6 ORY39934.1 - 0.027 13.8 3.5 0.19 11.0 2.1 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding LOH1CR12 PF10158.9 ORY39934.1 - 0.042 13.9 0.4 0.055 13.5 0.4 1.1 1 0 0 1 1 1 0 Tumour suppressor protein Lge1 PF11488.8 ORY39934.1 - 0.05 13.8 2.1 0.16 12.2 0.9 2.2 1 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 Prefoldin_2 PF01920.20 ORY39934.1 - 0.055 13.4 1.4 0.079 12.9 0.6 1.6 1 1 1 2 2 2 0 Prefoldin subunit Allexi_40kDa PF05549.11 ORY39934.1 - 0.067 12.7 0.4 0.067 12.7 0.4 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein PRKG1_interact PF15898.5 ORY39934.1 - 0.11 13.5 3.4 0.15 13.0 3.4 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF4298 PF14131.6 ORY39934.1 - 0.27 11.2 3.6 8 6.5 0.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4298) DivIC PF04977.15 ORY39934.1 - 0.46 10.3 4.6 0.6 9.9 1.4 2.2 1 1 1 2 2 2 0 Septum formation initiator Pkinase PF00069.25 ORY39935.1 - 1.6e-31 109.6 0.0 5.2e-31 108.0 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY39935.1 - 1.5e-21 76.8 0.0 2.3e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY39935.1 - 2.6e-05 24.3 0.2 0.05 13.5 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 ORY39935.1 - 6e-05 22.5 0.0 0.00013 21.4 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family bZIP_1 PF00170.21 ORY39935.1 - 0.02 15.0 0.9 0.02 15.0 0.9 1.7 2 0 0 2 2 2 0 bZIP transcription factor ADIP PF11559.8 ORY39935.1 - 0.14 12.2 0.7 0.25 11.4 0.7 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FHA PF00498.26 ORY39936.1 - 2.4e-07 31.0 0.3 4e-07 30.3 0.3 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 ORY39936.1 - 2e-05 24.8 0.1 2.9e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain BHD_3 PF10405.9 ORY39937.1 - 4.7e-21 75.0 0.0 8.6e-21 74.1 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 ORY39937.1 - 1.1e-13 50.8 0.0 2.2e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 ORY39937.1 - 1.1e-12 48.7 0.1 1.1e-12 48.7 0.1 2.5 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Rad4 PF03835.15 ORY39937.1 - 3.3e-06 26.8 0.1 3.3e-06 26.8 0.1 2.0 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 ORY39937.1 - 0.049 14.1 0.0 0.36 11.3 0.0 2.2 2 0 0 2 2 2 0 Transglutaminase-like superfamily T4SS_TraI PF16932.5 ORY39937.1 - 0.057 12.6 1.6 0.14 11.3 1.6 1.7 1 1 0 1 1 1 0 Type IV secretory system, conjugal DNA-protein transfer DLIC PF05783.11 ORY39938.1 - 1e-08 34.5 0.0 1.4e-06 27.4 0.0 2.2 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) Roc PF08477.13 ORY39938.1 - 3.2e-05 24.1 0.0 9.3e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORY39938.1 - 0.0017 18.0 0.0 0.33 10.5 0.0 2.5 2 0 0 2 2 2 2 Ras family SRPRB PF09439.10 ORY39938.1 - 0.026 13.9 0.0 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORY39938.1 - 0.18 11.9 0.1 0.43 10.7 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Cellulase PF00150.18 ORY39939.1 - 5.8e-06 25.9 2.3 1.2e-05 24.9 2.3 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.18 ORY39940.1 - 0.00045 19.7 1.6 0.0068 15.9 0.7 2.8 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) HTH_56 PF18662.1 ORY39940.1 - 0.098 12.7 0.1 0.24 11.5 0.1 1.6 1 0 0 1 1 1 0 Cch helix turn helix domain Glyco_hydro_cc PF11790.8 ORY39940.1 - 0.1 12.1 0.2 0.32 10.5 0.0 1.9 3 0 0 3 3 3 0 Glycosyl hydrolase catalytic core TPR_14 PF13428.6 ORY39941.1 - 0.089 13.7 0.8 1.3 10.1 0.2 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat RNA_pol_L_2 PF13656.6 ORY39942.1 - 3.3e-09 36.4 0.0 4.6e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Golgin_A5 PF09787.9 ORY39943.1 - 0.054 13.0 41.2 0.097 12.1 41.2 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 HTH_23 PF13384.6 ORY39943.1 - 0.069 13.0 0.1 0.54 10.1 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain PUL PF08324.11 ORY39946.1 - 3.8e-41 141.2 1.5 6e-41 140.5 1.5 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 ORY39946.1 - 1.5e-34 118.7 0.3 3.1e-34 117.6 0.1 1.7 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 ORY39946.1 - 6.5e-33 112.2 17.4 9.5e-07 29.4 0.0 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat BBS2_Mid PF14783.6 ORY39946.1 - 0.044 13.8 0.0 0.4 10.7 0.0 2.6 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DUF1160 PF06648.11 ORY39946.1 - 0.055 13.5 0.4 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1160) MFS_1 PF07690.16 ORY39947.1 - 1.2e-49 169.1 52.7 1.8e-49 168.6 52.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY39947.1 - 2.9e-11 42.9 13.9 2.9e-11 42.9 13.9 3.7 2 2 0 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.6 ORY39947.1 - 7.7 4.9 42.6 1.9 6.9 24.1 3.3 1 1 2 3 3 3 0 MFS/sugar transport protein CLASP_N PF12348.8 ORY39948.1 - 5.5e-32 111.1 0.0 5.6e-29 101.3 0.0 3.3 2 1 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 ORY39948.1 - 0.13 12.6 7.3 4 8.0 0.0 4.9 6 0 0 6 6 6 0 HEAT repeat LSM PF01423.22 ORY39949.1 - 7.8e-13 47.9 0.0 9.4e-13 47.7 0.0 1.0 1 0 0 1 1 1 1 LSM domain zinc_ribbon_16 PF17034.5 ORY39952.1 - 4.9e-15 55.9 19.2 1.7e-10 41.2 9.1 2.4 1 1 1 2 2 2 2 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 ORY39952.1 - 0.013 15.1 15.6 0.013 15.1 15.6 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Med26 PF08711.11 ORY39953.1 - 9.4e-08 32.0 0.3 2.6e-07 30.6 0.3 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-CCCH_2 PF14608.6 ORY39954.1 - 0.012 16.1 9.5 0.37 11.3 0.2 2.8 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 ORY39954.1 - 9 6.2 11.6 0.24 11.2 0.9 3.0 2 1 0 2 2 2 0 CCCH-type zinc finger CTP_transf_like PF01467.26 ORY39956.1 - 2.9e-24 85.9 0.0 4.3e-13 49.7 0.0 2.4 2 1 0 2 2 2 2 Cytidylyltransferase-like CTP_transf_like PF01467.26 ORY39957.1 - 2.1e-41 141.5 0.0 1.5e-25 90.1 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 ORY39957.1 - 0.0037 17.2 2.0 1.4 8.8 0.0 2.8 3 0 0 3 3 3 2 FAD synthetase PP2C PF00481.21 ORY39958.1 - 1.1e-20 74.4 0.0 1.3e-20 74.2 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C Sec1 PF00995.23 ORY39959.1 - 8.4e-128 428.1 0.0 9.5e-128 427.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family EF-hand_1 PF00036.32 ORY39960.1 - 2.5e-26 89.2 10.8 7.6e-08 31.4 0.5 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORY39960.1 - 6.8e-21 74.5 6.1 1.9e-13 50.6 1.6 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 ORY39960.1 - 1.8e-20 71.4 8.4 2.6e-07 29.8 0.4 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 ORY39960.1 - 2.1e-19 67.7 9.5 0.00013 21.7 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 ORY39960.1 - 5.7e-13 48.5 12.9 0.00027 20.7 0.6 4.3 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 ORY39960.1 - 6.5e-07 29.7 0.0 0.0034 17.7 0.1 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 ORY39960.1 - 0.00049 20.0 7.0 0.072 13.0 0.3 3.8 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 ORY39960.1 - 0.00057 20.2 0.2 0.22 11.9 0.1 3.0 2 1 1 3 3 3 1 EF-hand domain Dockerin_1 PF00404.18 ORY39960.1 - 0.4 10.9 3.4 1.6 8.9 1.7 2.6 2 1 0 2 2 2 0 Dockerin type I domain TMF_TATA_bd PF12325.8 ORY39961.1 - 4.1e-20 72.1 11.6 4.1e-20 72.1 11.6 7.2 2 1 5 8 8 8 3 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 ORY39961.1 - 9.9e-15 54.3 10.2 9.9e-15 54.3 10.2 9.3 4 3 7 11 11 11 2 TATA element modulatory factor 1 DNA binding Cast PF10174.9 ORY39961.1 - 0.00013 20.4 18.2 0.00013 20.4 18.2 3.1 2 1 1 3 3 3 1 RIM-binding protein of the cytomatrix active zone Filament PF00038.21 ORY39961.1 - 0.068 12.7 80.0 0.015 14.9 36.9 4.5 2 1 1 3 3 3 0 Intermediate filament protein Pox_A_type_inc PF04508.12 ORY39963.1 - 0.031 14.1 0.1 0.031 14.1 0.1 6.8 7 0 0 7 7 7 0 Viral A-type inclusion protein repeat MtrB PF05440.12 ORY39963.1 - 0.48 10.9 6.9 15 6.1 0.1 4.4 4 1 1 5 5 5 0 Tetrahydromethanopterin S-methyltransferase subunit B Filament PF00038.21 ORY39963.1 - 8.8 5.8 111.0 0.48 9.9 7.0 5.6 2 1 4 6 6 6 0 Intermediate filament protein Peptidase_C65 PF10275.9 ORY39964.1 - 7.5e-46 156.6 0.2 1.4e-45 155.6 0.2 1.4 1 1 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 ORY39964.1 - 9.1e-05 23.0 0.0 0.012 16.1 0.0 2.1 2 0 0 2 2 2 2 OTU-like cysteine protease PQ-loop PF04193.14 ORY39965.1 - 1.7e-20 72.5 2.9 2.4e-20 72.1 2.9 1.2 1 0 0 1 1 1 1 PQ loop repeat Cytochrom_C_asm PF01578.20 ORY39965.1 - 0.025 14.3 1.2 0.029 14.1 1.2 1.1 1 0 0 1 1 1 0 Cytochrome C assembly protein RRM_1 PF00076.22 ORY39966.1 - 3e-18 65.4 2.2 6.6e-10 38.7 0.1 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY39966.1 - 0.0059 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif RRM_occluded PF16842.5 ORY39966.1 - 0.22 11.4 1.6 6 6.8 0.0 2.9 4 0 0 4 4 4 0 Occluded RNA-recognition motif Stap_Strp_tox_C PF02876.17 ORY39966.1 - 0.33 11.3 3.7 0.28 11.5 0.3 2.4 1 1 2 3 3 3 0 Staphylococcal/Streptococcal toxin, beta-grasp domain RNA_pol_Rpc4 PF05132.14 ORY39966.1 - 0.62 10.5 5.1 0.43 11.0 0.4 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 cobW PF02492.19 ORY39967.1 - 4.3e-32 111.1 0.0 5.7e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 ORY39967.1 - 9.5e-05 21.5 0.1 0.01 14.9 0.0 2.1 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 ORY39967.1 - 0.00034 20.7 0.0 0.00075 19.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 ORY39967.1 - 0.032 14.7 0.0 0.045 14.3 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 ORY39967.1 - 0.058 13.9 0.0 0.1 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 ORY39967.1 - 0.059 13.4 0.0 0.081 12.9 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit GHMP_kinases_C PF08544.13 ORY39967.1 - 0.062 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 GHMP kinases C terminal Phos_pyr_kin PF08543.12 ORY39969.1 - 6.2e-17 61.8 0.0 8.6e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 ORY39969.1 - 2.5e-15 56.6 0.0 3.6e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase IFT46_B_C PF12317.8 ORY39970.1 - 1.3e-79 266.9 0.3 1.8e-79 266.4 0.3 1.2 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Cullin PF00888.22 ORY39971.1 - 1.2e-184 615.5 13.5 1.5e-184 615.1 13.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 ORY39971.1 - 3.4e-25 87.9 5.5 1.1e-24 86.2 5.5 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF4423 PF14394.6 ORY39971.1 - 0.012 15.3 4.4 0.76 9.5 0.3 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4423) Penicillinase_R PF03965.16 ORY39971.1 - 0.03 14.7 0.1 0.03 14.7 0.1 3.8 4 0 0 4 4 4 0 Penicillinase repressor Glutaminase PF04960.15 ORY39971.1 - 0.053 12.7 0.1 0.053 12.7 0.1 1.9 2 0 0 2 2 2 0 Glutaminase Op_neuropeptide PF08035.11 ORY39971.1 - 0.12 12.3 0.5 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 Opioids neuropeptide Phage_rep_org_N PF09681.10 ORY39971.1 - 0.13 12.2 3.5 5.1 7.1 0.2 3.2 3 0 0 3 3 3 0 N-terminal phage replisome organiser (Phage_rep_org_N) Phage_TAC_12 PF12363.8 ORY39971.1 - 0.16 12.4 0.2 0.16 12.4 0.2 3.3 5 1 0 5 5 5 0 Phage tail assembly chaperone protein, TAC Fn_bind PF02986.14 ORY39971.1 - 0.81 9.5 3.0 1.1 9.0 0.6 2.3 2 0 0 2 2 2 0 Fibronectin binding repeat WD40 PF00400.32 ORY39972.1 - 8e-18 64.5 14.3 0.0011 19.7 0.6 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY39972.1 - 0.00039 20.7 0.0 11 6.3 0.0 4.3 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Zn_Tnp_IS1595 PF12760.7 ORY39972.1 - 0.039 13.9 0.3 0.071 13.1 0.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Radial_spoke PF04712.12 ORY39972.1 - 0.18 10.7 3.9 0.29 10.0 3.9 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein PhnA_Zn_Ribbon PF08274.12 ORY39972.1 - 0.31 11.0 2.2 0.51 10.3 0.2 2.1 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Ribosomal_L44 PF00935.19 ORY39972.1 - 0.33 11.5 1.2 0.79 10.2 0.2 2.2 2 0 0 2 2 2 0 Ribosomal protein L44 CDC45 PF02724.14 ORY39972.1 - 0.92 7.7 5.9 1.6 6.9 5.9 1.3 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 ORY39972.1 - 0.97 8.8 10.7 2 7.8 10.7 1.5 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 ORY39972.1 - 1.8 6.7 13.9 2.8 6.0 13.9 1.2 1 0 0 1 1 1 0 Nop14-like family Mito_carr PF00153.27 ORY39973.1 - 2.8e-43 145.8 1.3 1.8e-16 59.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein GTP_EFTU PF00009.27 ORY39975.1 - 7.4e-63 211.6 0.2 1.6e-62 210.5 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 ORY39975.1 - 3.1e-32 110.9 0.7 8.6e-32 109.5 0.5 1.9 1 1 1 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.6 ORY39975.1 - 6e-31 106.4 0.0 1.5e-30 105.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 ORY39975.1 - 3.1e-25 88.0 0.4 9.3e-25 86.5 0.1 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORY39975.1 - 9.5e-13 48.4 0.1 4.4e-12 46.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 ORY39975.1 - 6.5e-06 26.0 0.0 3e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 ORY39975.1 - 9.3e-05 22.5 0.1 0.00027 21.0 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 ORY39975.1 - 0.0065 15.8 0.1 0.022 14.1 0.0 1.8 2 0 0 2 2 2 1 AIG1 family FeoB_N PF02421.18 ORY39975.1 - 0.045 13.3 0.0 0.14 11.7 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B PAC4 PF16093.5 ORY39976.1 - 1.9e-18 66.4 0.1 3.2e-18 65.7 0.1 1.4 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 Mito_carr PF00153.27 ORY39977.1 - 3.5e-23 81.4 3.2 6.2e-14 51.7 0.1 3.1 3 0 0 3 3 3 2 Mitochondrial carrier protein Pyr_redox_2 PF07992.14 ORY39981.1 - 8.4e-07 28.5 0.2 3e-06 26.7 0.3 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY39981.1 - 0.004 17.2 0.5 1 9.4 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding K_oxygenase PF13434.6 ORY39981.1 - 0.0093 15.1 0.2 0.023 13.8 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ORY39981.1 - 0.063 12.5 2.5 0.59 9.3 1.9 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Toxin_R_bind_N PF07953.12 ORY39981.1 - 0.16 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Clostridium neurotoxin, N-terminal receptor binding ADH_zinc_N_2 PF13602.6 ORY39982.1 - 2.5e-25 90.1 0.0 4.6e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY39982.1 - 9.5e-16 58.0 1.2 1.7e-15 57.2 1.1 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY39982.1 - 1.9e-06 27.7 0.1 2e-05 24.4 0.0 2.5 1 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 ORY39982.1 - 0.019 14.4 0.3 0.032 13.7 0.3 1.3 1 0 0 1 1 1 0 short chain dehydrogenase Epimerase PF01370.21 ORY39982.1 - 0.048 13.1 0.2 0.32 10.4 0.1 2.3 2 1 1 3 3 3 0 NAD dependent epimerase/dehydratase family Peptidase_M13_N PF05649.13 ORY39983.1 - 3.8e-62 211.2 0.8 6.6e-61 207.1 0.8 2.3 1 1 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 ORY39983.1 - 2.2e-36 125.4 6.2 1.3e-24 87.0 0.1 3.3 2 1 1 3 3 3 3 Peptidase family M13 Peptidase_M48 PF01435.18 ORY39983.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M48 zf-RING_2 PF13639.6 ORY39984.1 - 8.5e-12 45.2 9.5 8.5e-12 45.2 9.5 2.0 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORY39984.1 - 7.3e-10 38.6 5.7 1.5e-09 37.5 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY39984.1 - 3.8e-08 33.5 9.0 1.2e-07 32.0 9.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 ORY39984.1 - 8.7e-08 32.0 8.3 1.7e-07 31.1 8.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ORY39984.1 - 1.2e-07 31.4 9.8 1.4e-07 31.2 7.6 2.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY39984.1 - 3.3e-07 30.1 5.3 3.9e-07 29.8 3.8 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY39984.1 - 2.3e-06 27.5 4.2 2.3e-06 27.5 4.2 2.5 2 1 1 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 ORY39984.1 - 3.2e-06 26.9 11.6 3.1e-05 23.8 11.4 2.6 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 ORY39984.1 - 3.5e-06 27.0 5.2 7e-06 26.0 5.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 ORY39984.1 - 0.0012 18.5 7.5 0.0029 17.4 7.5 1.6 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain CEBP_ZZ PF16366.5 ORY39984.1 - 0.0015 18.7 0.8 0.0015 18.7 0.8 2.5 2 0 0 2 2 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain Rtf2 PF04641.12 ORY39984.1 - 0.0049 16.3 5.8 0.0049 16.3 5.8 2.4 1 1 0 2 2 2 1 Rtf2 RING-finger zf-P11 PF03854.14 ORY39984.1 - 0.036 13.7 8.3 0.082 12.6 8.3 1.6 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_4 PF15227.6 ORY39984.1 - 0.062 13.5 14.3 0.27 11.4 13.0 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Cys_rich_CPXG PF14255.6 ORY39984.1 - 0.077 12.9 3.5 0.78 9.7 0.6 2.7 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-C3HC4_5 PF17121.5 ORY39984.1 - 0.34 10.8 4.7 0.8 9.6 4.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 ORY39984.1 - 0.38 10.7 8.1 0.38 10.7 6.7 1.7 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-Di19 PF05605.12 ORY39984.1 - 0.47 10.8 8.1 2 8.8 1.4 2.9 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.21 ORY39984.1 - 0.54 10.5 13.6 0.5 10.6 9.7 2.4 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain PRCC PF10253.9 ORY39984.1 - 1.1 10.0 13.0 2 9.2 13.0 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DZR PF12773.7 ORY39984.1 - 1.6 8.8 8.1 5.7 7.0 8.2 1.9 1 1 0 1 1 1 0 Double zinc ribbon TerY_C PF15616.6 ORY39984.1 - 1.8 8.6 9.2 0.53 10.4 6.1 1.6 2 0 0 2 2 1 0 TerY-C metal binding domain zf-RING_11 PF17123.5 ORY39984.1 - 9.2 6.1 11.9 0.78 9.5 4.3 2.8 3 0 0 3 3 3 0 RING-like zinc finger zf-RING_6 PF14835.6 ORY39984.1 - 9.7 6.1 10.9 28 4.7 9.2 2.3 1 1 1 2 2 2 0 zf-RING of BARD1-type protein NDK PF00334.19 ORY39985.1 - 5.5e-143 470.0 0.0 1.4e-39 135.2 0.0 4.8 5 0 0 5 5 5 4 Nucleoside diphosphate kinase Thioredoxin PF00085.20 ORY39985.1 - 1.6e-06 28.0 0.0 4.1e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin PASTA PF03793.19 ORY39985.1 - 0.003 17.4 0.3 1.8 8.4 0.0 2.6 2 0 0 2 2 2 2 PASTA domain IQCJ-SCHIP1 PF15157.6 ORY39985.1 - 0.0054 16.6 0.4 0.04 13.7 0.0 2.5 2 0 0 2 2 2 1 Fusion protein IQCJ-SCHIP1 with IQ-like motif DUF2795 PF11387.8 ORY39985.1 - 0.039 14.2 0.1 16 5.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2795) Glyco_hydro_26 PF02156.15 ORY39986.1 - 9.6e-09 35.1 0.3 1.5e-08 34.5 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 RVT_connect PF06815.13 ORY39986.1 - 0.089 13.1 0.6 5 7.4 0.0 2.6 1 1 0 2 2 2 0 Reverse transcriptase connection domain V-ATPase_C PF03223.15 ORY39987.1 - 6.1e-136 453.7 4.9 6.8e-136 453.5 4.9 1.0 1 0 0 1 1 1 1 V-ATPase subunit C 14-3-3 PF00244.20 ORY39988.1 - 1.2e-106 355.2 0.8 1.4e-106 355.0 0.8 1.0 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 ORY39988.1 - 0.058 13.4 0.3 0.11 12.5 0.3 1.5 1 0 0 1 1 1 0 Flagellar protein FlaF MORN PF02493.20 ORY39989.1 - 4e-14 51.6 15.7 1.2e-07 31.1 3.6 3.7 4 0 0 4 4 4 3 MORN repeat DUF3048_C PF17479.2 ORY39989.1 - 0.13 12.7 2.5 1.3 9.4 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3048) C-terminal domain Pkinase PF00069.25 ORY39990.1 - 1.6e-64 217.8 0.0 1.8e-64 217.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY39990.1 - 3.5e-45 154.3 0.0 4.3e-45 154.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY39990.1 - 1.7e-07 30.4 0.0 2.3e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY39990.1 - 5.7e-05 22.6 0.0 8.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 ORY39990.1 - 0.0013 18.4 0.0 0.0029 17.2 0.0 1.6 1 1 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 ORY39990.1 - 0.031 13.2 0.0 0.082 11.8 0.0 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 ORY39990.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY39990.1 - 0.15 11.9 0.0 3.8 7.4 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family CNH PF00780.22 ORY39991.1 - 4.3e-06 26.5 0.1 8e-06 25.7 0.1 1.4 1 1 0 1 1 1 1 CNH domain ANAPC4_WD40 PF12894.7 ORY39991.1 - 0.00044 20.5 0.0 0.006 16.8 0.1 2.4 1 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Mpv17_PMP22 PF04117.12 ORY39991.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Mpv17 / PMP22 family zf-CpG_bind_C PF12269.8 ORY39992.1 - 6.2e-07 29.4 0.9 1.3e-06 28.4 0.9 1.5 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain PHD PF00628.29 ORY39993.1 - 7.3e-10 38.6 8.3 1.2e-09 37.9 8.3 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORY39993.1 - 0.0021 17.6 1.7 0.0021 17.6 1.7 1.8 2 0 0 2 2 2 1 PHD-finger AMP-binding PF00501.28 ORY39994.1 - 1.4e-48 165.5 0.0 2.1e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.24 ORY39994.1 - 3.1e-13 48.9 5.9 9.8e-07 28.3 0.1 6.0 6 1 1 7 7 7 2 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.25 ORY39994.1 - 7.3e-09 35.9 0.0 2.1e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 ORY39994.1 - 1.5e-07 32.3 0.0 0.0007 20.5 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Hexapep_2 PF14602.6 ORY39994.1 - 0.00012 21.7 6.7 0.023 14.5 0.3 4.2 5 0 0 5 5 5 2 Hexapeptide repeat of succinyl-transferase GH3 PF03321.13 ORY39994.1 - 0.051 12.4 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 GH3 auxin-responsive promoter PC4 PF02229.16 ORY39995.1 - 3.1e-18 65.1 0.9 3.1e-18 65.1 0.9 1.5 2 0 0 2 2 2 1 Transcriptional Coactivator p15 (PC4) HUN PF08729.10 ORY39995.1 - 0.034 14.1 0.6 0.034 14.1 0.6 2.2 2 0 0 2 2 2 0 HPC2 and ubinuclein domain RNA_polI_A14 PF08203.11 ORY39995.1 - 0.045 14.5 0.8 0.073 13.8 0.8 1.3 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Med4 PF10018.9 ORY39996.1 - 2.4e-08 33.9 10.0 1.5e-07 31.3 10.0 1.9 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Cgr1 PF03879.14 ORY39996.1 - 0.035 14.5 2.7 0.061 13.7 2.7 1.4 1 0 0 1 1 1 0 Cgr1 family LMBR1 PF04791.16 ORY39996.1 - 0.21 10.5 2.0 0.2 10.5 2.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein FOXP-CC PF16159.5 ORY39996.1 - 0.83 10.3 5.1 0.24 12.1 1.8 1.8 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-CpG_bind_C PF12269.8 ORY39996.1 - 1.7 8.4 6.3 0.12 12.1 1.5 1.5 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain HEAT_2 PF13646.6 ORY39997.1 - 3.8e-19 68.9 0.1 1.1e-09 38.6 0.0 4.6 4 1 0 4 4 4 3 HEAT repeats HEAT PF02985.22 ORY39997.1 - 3.9e-06 26.7 5.8 19 5.9 0.0 7.9 8 1 1 9 9 9 1 HEAT repeat HEAT_PBS PF03130.16 ORY39997.1 - 0.00013 22.3 0.1 1.7 9.6 0.0 3.7 3 0 0 3 3 3 2 PBS lyase HEAT-like repeat Cnd1 PF12717.7 ORY39997.1 - 0.012 15.6 2.2 0.64 10.0 0.4 3.7 3 1 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 ORY39997.1 - 0.021 13.4 0.1 0.049 12.2 0.0 1.6 1 1 0 1 1 1 0 Adaptin N terminal region DUF4042 PF13251.6 ORY39997.1 - 0.13 11.9 0.2 25 4.5 0.0 3.8 3 1 0 4 4 4 0 Domain of unknown function (DUF4042) Vac14_Fab1_bd PF12755.7 ORY39997.1 - 0.18 12.4 0.4 2.6 8.7 0.1 3.0 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region Polysacc_deac_1 PF01522.21 ORY39998.1 - 1.4e-14 54.0 0.0 2.6e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Transthyretin PF00576.21 ORY39999.1 - 1.1e-28 100.1 0.1 1.3e-28 99.8 0.1 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family MG4 PF17789.1 ORY39999.1 - 0.0017 18.5 0.1 0.0026 17.9 0.1 1.3 1 0 0 1 1 1 1 Macroglobulin domain MG4 Big_1 PF02369.16 ORY39999.1 - 0.035 14.1 1.0 0.064 13.3 1.0 1.5 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 1) OHCU_decarbox PF09349.10 ORY40000.1 - 1.9e-34 119.4 0.0 2.1e-34 119.3 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase APG6 PF04111.12 ORY40001.1 - 2.3e-71 239.4 0.0 4e-71 238.7 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 ORY40001.1 - 4.5e-20 72.5 23.0 7.7e-20 71.8 23.0 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region Activator_LAG-3 PF11498.8 ORY40001.1 - 0.26 10.2 6.0 0.37 9.7 6.0 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 VPS38 PF17649.1 ORY40001.1 - 1.3 7.8 7.5 2 7.2 0.0 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting 38 FapA PF03961.13 ORY40001.1 - 1.6 7.2 5.4 2.3 6.7 5.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Jnk-SapK_ap_N PF09744.9 ORY40001.1 - 5.2 7.3 21.4 2.1 8.5 18.4 1.7 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Atg14 PF10186.9 ORY40001.1 - 5.7 5.9 13.5 9.5 5.2 11.5 2.0 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 7tm_3 PF00003.22 ORY40002.1 - 1.6e-12 47.7 5.4 5.4e-12 46.0 5.4 1.9 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 ORY40002.1 - 2e-12 46.9 0.1 3.1e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region DUF642 PF04862.12 ORY40003.1 - 0.054 13.3 0.1 0.07 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF642) ThiF PF00899.21 ORY40005.1 - 2.2e-106 354.7 0.0 1.9e-70 237.0 0.0 2.2 1 1 1 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 ORY40005.1 - 1.7e-97 326.3 0.7 2.1e-95 319.5 0.6 2.2 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 ORY40005.1 - 2.9e-35 120.8 0.3 7.8e-35 119.5 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 ORY40005.1 - 2.8e-34 117.1 0.3 6.6e-34 115.9 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 ORY40005.1 - 5.1e-21 74.6 0.9 1.2e-20 73.4 0.9 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle CBP_BcsR PF10945.8 ORY40005.1 - 0.14 11.6 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsR Shikimate_DH PF01488.20 ORY40005.1 - 0.19 11.8 0.3 4.7 7.3 0.1 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DEAD PF00270.29 ORY40006.1 - 2.9e-41 141.2 0.0 5.9e-41 140.1 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY40006.1 - 4.6e-13 49.5 1.0 6.5e-09 36.1 0.0 3.1 2 1 1 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 ORY40006.1 - 0.00012 22.1 0.0 0.00021 21.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 ORY40006.1 - 0.00037 20.2 0.0 0.0093 15.7 0.0 2.1 1 1 0 1 1 1 1 SWI2/SNF2 ATPase GST_N_3 PF13417.6 ORY40006.1 - 0.066 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain MSL1_dimer PF16801.5 ORY40007.1 - 0.11 12.2 1.4 0.33 10.7 1.4 1.8 1 0 0 1 1 1 0 Dimerisation domain of Male-specific-Lethal 1 PCI PF01399.27 ORY40007.1 - 0.22 12.1 5.9 0.92 10.1 0.0 4.0 4 0 0 4 4 4 0 PCI domain RMI1_N PF08585.12 ORY40082.1 - 8.6e-23 81.2 0.1 1e-22 81.0 0.1 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein Fzo_mitofusin PF04799.13 ORY40083.1 - 0.14 11.7 3.4 0.21 11.2 1.5 1.9 1 1 1 2 2 2 0 fzo-like conserved region CutA1 PF03091.15 ORY40085.1 - 8.9e-35 118.5 0.2 1e-34 118.4 0.2 1.0 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Sel1 PF08238.12 ORY40086.1 - 1.1e-32 111.7 18.5 2.6e-08 34.3 0.6 6.4 5 2 1 6 6 6 6 Sel1 repeat TPR_16 PF13432.6 ORY40086.1 - 2.9e-08 34.2 0.1 0.062 14.0 0.0 4.4 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY40086.1 - 3.7e-05 23.9 4.0 0.41 11.0 0.1 4.6 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY40086.1 - 0.001 18.8 13.5 0.086 12.7 0.2 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY40086.1 - 0.001 19.0 9.9 0.37 11.0 0.0 6.1 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY40086.1 - 0.02 15.3 10.5 10 6.7 0.0 5.7 4 2 1 5 5 5 0 Tetratricopeptide repeat DUF5112 PF17139.4 ORY40086.1 - 0.069 12.6 0.5 0.52 9.8 0.1 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF5112) YcbB PF08664.10 ORY40086.1 - 0.079 13.0 0.0 11 6.1 0.0 2.2 2 0 0 2 2 2 0 YcbB domain TPR_7 PF13176.6 ORY40086.1 - 0.16 12.1 0.5 11 6.3 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY40086.1 - 0.32 11.3 12.7 22 5.6 0.0 5.6 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY40086.1 - 1.3 9.0 12.4 0.33 10.9 0.3 4.6 5 1 0 5 5 5 0 Tetratricopeptide repeat RhoGEF PF00621.20 ORY40087.1 - 1.5e-31 110.1 2.4 2.3e-31 109.4 2.4 1.3 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.6 ORY40087.1 - 2e-07 31.3 0.1 3.5e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain RabGAP-TBC PF00566.18 ORY40087.1 - 0.081 12.6 0.3 0.15 11.7 0.3 1.4 1 0 0 1 1 1 0 Rab-GTPase-TBC domain PH_10 PF15411.6 ORY40088.1 - 2.4e-25 89.2 0.0 4.4e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 ORY40088.1 - 2.6e-24 86.5 4.6 4.4e-24 85.7 4.6 1.4 1 0 0 1 1 1 1 RhoGEF domain CDC24 PF06395.11 ORY40088.1 - 1.1e-16 60.9 0.0 2.8e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 CDC24 Calponin DUF493 PF04359.14 ORY40088.1 - 0.14 12.7 0.1 0.36 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF493) PH PF00169.29 ORY40088.1 - 0.15 12.6 0.0 0.39 11.3 0.0 1.7 1 0 0 1 1 1 0 PH domain Rab5ip PF07019.12 ORY40089.1 - 7.8e-16 58.4 8.5 2.3e-15 56.9 8.5 1.8 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Lipase_GDSL PF00657.22 ORY40089.1 - 2.6e-10 40.6 0.1 5.6e-10 39.5 0.1 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY40089.1 - 0.007 16.8 6.8 0.028 14.8 6.8 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF4865 PF16157.5 ORY40089.1 - 0.12 12.3 0.1 0.2 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4865) SET PF00856.28 ORY40091.1 - 4.3e-19 69.5 1.1 2.2e-18 67.2 0.1 2.4 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.16 ORY40091.1 - 8e-08 32.9 8.1 8e-08 32.9 8.1 2.1 2 0 0 2 2 2 1 Pre-SET motif CNRIP1 PF15043.6 ORY40091.1 - 0.032 13.8 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 CB1 cannabinoid receptor-interacting protein 1 Prefoldin_3 PF13758.6 ORY40092.1 - 0.2 11.7 1.5 0.43 10.7 0.2 2.2 2 0 0 2 2 2 0 Prefoldin subunit WD40 PF00400.32 ORY40093.1 - 5.1e-13 49.3 17.7 7.4e-05 23.4 0.3 7.1 7 1 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.8 ORY40093.1 - 1.2e-08 34.1 8.0 0.00081 18.2 0.0 3.4 2 1 1 3 3 3 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 ORY40093.1 - 0.00021 21.5 0.7 3.6 7.9 0.0 4.5 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 ORY40093.1 - 0.041 12.8 0.2 0.13 11.2 0.0 1.9 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain SH3_9 PF14604.6 ORY40094.1 - 3.2e-25 87.7 0.0 7.2e-08 32.2 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 ORY40094.1 - 3.3e-17 61.8 0.0 0.00016 21.2 0.0 3.5 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 ORY40094.1 - 1e-06 28.3 0.0 0.22 11.2 0.0 3.5 3 0 0 3 3 3 2 Variant SH3 domain TMEM154 PF15102.6 ORY40094.1 - 0.038 13.9 0.6 0.038 13.9 0.6 3.1 2 1 0 2 2 2 0 TMEM154 protein family DUF347 PF03988.12 ORY40094.1 - 0.047 13.9 0.2 0.13 12.4 0.2 1.8 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) SapA PF02199.15 ORY40094.1 - 0.26 11.6 1.5 0.64 10.4 1.5 1.7 1 0 0 1 1 1 0 Saposin A-type domain COesterase PF00135.28 ORY40096.1 - 8.2e-49 166.8 0.0 9.2e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family DUF4141 PF13605.6 ORY40096.1 - 0.11 11.7 0.1 0.2 10.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) Amino_oxidase PF01593.24 ORY40098.1 - 1.5e-17 64.1 0.1 3.9e-08 33.0 0.0 2.7 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY40098.1 - 6.2e-12 45.6 0.1 1.2e-11 44.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY40098.1 - 1.2e-08 34.5 0.0 1.5e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY40098.1 - 5.4e-08 32.8 0.0 3.3e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ORY40098.1 - 2.9e-05 23.6 0.2 5.1e-05 22.8 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY40098.1 - 3.9e-05 22.9 1.6 8.2e-05 21.9 1.6 1.5 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 ORY40098.1 - 0.00021 20.7 0.6 0.00038 19.8 0.6 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ORY40098.1 - 0.0047 15.7 1.3 0.0087 14.8 1.3 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 ORY40098.1 - 0.0049 16.1 0.4 0.0086 15.3 0.4 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 ORY40098.1 - 0.0087 15.2 1.9 0.0087 15.2 1.9 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.27 ORY40098.1 - 0.01 16.4 2.3 0.082 13.5 1.4 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 ORY40098.1 - 0.016 14.1 0.1 2 7.1 0.0 2.1 2 0 0 2 2 2 0 MCRA family Pyr_redox_3 PF13738.6 ORY40098.1 - 0.018 14.3 1.1 0.1 11.8 1.7 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY40098.1 - 0.02 14.9 2.5 0.12 12.3 1.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 ORY40098.1 - 0.023 14.0 0.7 0.047 12.9 0.7 1.5 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 ORY40098.1 - 0.035 13.7 0.7 0.1 12.2 0.2 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 ORY40098.1 - 0.064 12.9 0.1 0.13 11.9 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 ORY40098.1 - 0.11 12.7 0.4 0.23 11.7 0.1 1.7 2 0 0 2 2 1 0 TrkA-N domain F420_oxidored PF03807.17 ORY40098.1 - 0.18 12.4 0.9 0.52 10.9 0.9 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Trp_halogenase PF04820.14 ORY40098.1 - 0.31 9.8 2.3 0.41 9.4 1.2 1.7 2 0 0 2 2 2 0 Tryptophan halogenase ANAPC15 PF15243.6 ORY40099.1 - 0.00021 21.6 0.4 0.00021 21.6 0.4 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 15 FMP23 PF17315.2 ORY40099.1 - 0.04 14.1 0.6 1.7 8.8 0.0 2.7 2 0 0 2 2 2 0 Found in mitochondrial proteome KilA-N PF04383.13 ORY40099.1 - 0.51 10.2 3.7 0.39 10.6 0.3 2.6 3 0 0 3 3 3 0 KilA-N domain DUF1387 PF07139.11 ORY40100.1 - 0.006 16.4 1.7 0.0097 15.7 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1387) Phostensin PF13914.6 ORY40100.1 - 0.016 15.8 1.7 0.037 14.7 1.7 1.7 1 0 0 1 1 1 0 Phostensin PP1-binding and SH3-binding region RRM_1 PF00076.22 ORY40102.1 - 4.6e-22 77.6 0.0 6.6e-10 38.7 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY40102.1 - 2.8e-06 27.4 0.0 0.0011 19.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif Phytochelatin PF05023.14 ORY40102.1 - 0.18 11.0 0.0 9.4 5.4 0.0 2.1 2 0 0 2 2 2 0 Phytochelatin synthase BAG PF02179.16 ORY40103.1 - 4.6e-12 46.2 0.8 9.3e-12 45.2 0.8 1.5 1 0 0 1 1 1 1 BAG domain PRCC PF10253.9 ORY40103.1 - 0.17 12.7 3.8 0.17 12.6 3.8 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Asp PF00026.23 ORY40104.1 - 2.3e-37 129.1 5.9 2.2e-36 125.9 5.9 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY40104.1 - 4.3e-17 62.9 6.0 5.9e-17 62.5 6.0 1.2 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal DUF4796 PF16044.5 ORY40104.1 - 0.013 15.1 0.1 0.017 14.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) Asp PF00026.23 ORY40105.1 - 2.9e-24 86.1 0.4 3.2e-24 85.9 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 ORY40105.1 - 4.9e-08 32.9 0.2 2.2e-07 30.8 0.2 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal BAG PF02179.16 ORY40107.1 - 2.5e-08 34.2 0.3 4.9e-08 33.3 0.1 1.7 2 0 0 2 2 2 1 BAG domain zf-Di19 PF05605.12 ORY40107.1 - 0.03 14.6 2.7 0.055 13.8 2.7 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding IQ PF00612.27 ORY40107.1 - 0.069 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif ABC_tran PF00005.27 ORY40108.1 - 8.5e-57 191.5 0.6 5e-32 111.3 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORY40108.1 - 2.3e-25 89.8 38.4 6.7e-14 52.2 11.8 3.1 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ORY40108.1 - 5.4e-11 42.3 7.0 0.00012 21.6 1.9 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY40108.1 - 4.3e-08 32.8 2.9 0.00025 20.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 ORY40108.1 - 3.7e-07 30.3 2.3 0.036 13.9 0.0 4.2 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 ORY40108.1 - 1.1e-06 28.6 1.1 0.0093 16.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF87 PF01935.17 ORY40108.1 - 3.9e-06 27.1 5.5 0.0012 19.0 0.2 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_16 PF13191.6 ORY40108.1 - 1.7e-05 25.3 0.8 0.25 11.7 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 ORY40108.1 - 3.9e-05 24.3 0.4 0.093 13.2 0.1 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ORY40108.1 - 8.5e-05 22.5 0.8 0.26 11.2 0.2 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 ORY40108.1 - 0.00032 21.0 1.2 0.32 11.3 0.1 3.2 3 1 0 3 3 2 1 AAA domain AAA_30 PF13604.6 ORY40108.1 - 0.00036 20.3 2.1 0.2 11.4 0.1 2.7 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 ORY40108.1 - 0.0004 20.3 2.1 0.36 10.7 0.1 3.1 3 0 0 3 3 2 2 NACHT domain TrwB_AAD_bind PF10412.9 ORY40108.1 - 0.00051 19.1 1.5 0.24 10.3 0.1 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain T2SSE PF00437.20 ORY40108.1 - 0.00068 18.8 0.3 0.28 10.2 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 ORY40108.1 - 0.0014 18.1 1.1 0.6 9.6 0.1 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Ploopntkinase3 PF18751.1 ORY40108.1 - 0.0024 17.8 0.4 2.1 8.3 0.0 2.4 2 0 0 2 2 2 2 P-loop Nucleotide Kinase3 NB-ARC PF00931.22 ORY40108.1 - 0.0031 16.7 1.0 0.18 10.9 0.2 2.4 2 0 0 2 2 2 1 NB-ARC domain FtsK_SpoIIIE PF01580.18 ORY40108.1 - 0.0036 16.7 0.7 2.8 7.2 0.1 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family RNA_helicase PF00910.22 ORY40108.1 - 0.0045 17.4 0.1 2.4 8.6 0.0 2.9 2 0 0 2 2 2 1 RNA helicase Roc PF08477.13 ORY40108.1 - 0.005 17.1 0.3 2.4 8.4 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 ORY40108.1 - 0.0054 16.3 0.2 0.53 9.8 0.2 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 ORY40108.1 - 0.0069 16.5 3.1 0.65 10.0 0.8 2.7 2 0 0 2 2 2 1 Dynamin family AAA_33 PF13671.6 ORY40108.1 - 0.023 14.9 1.1 9.9 6.3 0.7 2.6 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 ORY40108.1 - 0.032 13.2 0.8 0.45 9.4 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 ORY40108.1 - 0.033 13.8 0.3 8.2 6.0 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 ORY40108.1 - 0.038 13.3 3.7 0.74 9.1 0.2 2.8 3 0 0 3 3 3 0 Zeta toxin ATP-synt_ab PF00006.25 ORY40108.1 - 0.04 13.6 0.1 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.17 ORY40108.1 - 0.053 13.3 2.0 2.3 7.9 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 ORY40108.1 - 0.086 12.4 0.3 1.3 8.6 0.0 2.5 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain Sigma54_activat PF00158.26 ORY40108.1 - 0.11 12.2 0.2 14 5.4 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_15 PF13175.6 ORY40108.1 - 0.14 11.8 4.9 2.3 7.8 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain AAA_18 PF13238.6 ORY40108.1 - 0.26 11.9 0.6 12 6.5 0.1 2.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 ORY40108.1 - 0.26 11.2 1.5 2.6 7.9 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 ORY40108.1 - 0.41 10.2 2.8 17 4.9 0.8 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 ORY40108.1 - 0.72 10.1 2.0 14 5.9 0.8 2.4 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 ORY40108.1 - 0.75 9.2 5.0 1.9 7.9 0.1 2.8 3 0 0 3 3 3 0 Poxvirus A32 protein SWIRM PF04433.17 ORY40109.1 - 8.3e-06 26.1 0.0 1.8e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain FAM176 PF14851.6 ORY40110.1 - 0.037 13.7 0.7 0.07 12.8 0.7 1.3 1 0 0 1 1 1 0 FAM176 family O-FucT PF10250.9 ORY40110.1 - 0.091 12.4 0.0 0.33 10.6 0.0 1.9 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Pkinase PF00069.25 ORY40111.1 - 9e-05 22.0 0.0 0.00011 21.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF1847 PF08901.11 ORY40111.1 - 0.049 13.3 0.0 0.068 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1847) Pkinase_Tyr PF07714.17 ORY40111.1 - 0.056 12.7 0.0 0.089 12.1 0.0 1.3 1 1 0 1 1 1 0 Protein tyrosine kinase Choline_kinase PF01633.20 ORY40112.1 - 0.009 15.6 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 ORY40112.1 - 0.037 13.4 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain SNF2_N PF00176.23 ORY40113.1 - 1.4e-55 188.4 0.0 2.5e-55 187.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY40113.1 - 6.9e-17 61.8 0.0 1.9e-16 60.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY40113.1 - 5.7e-12 46.0 0.0 1.3e-11 44.8 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 ORY40113.1 - 3e-08 33.2 0.1 1.6e-07 30.8 0.1 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 ORY40113.1 - 1.7e-05 24.7 0.0 4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 ORY40113.1 - 0.00042 20.1 0.0 0.00082 19.1 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase ABC_membrane PF00664.23 ORY40113.1 - 0.15 11.6 0.1 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region FAM199X PF15814.5 ORY40114.1 - 0.2 10.7 2.0 0.24 10.4 2.0 1.1 1 0 0 1 1 1 0 Protein family FAM199X TM231 PF10149.9 ORY40115.1 - 2.5e-33 115.7 6.7 1.8e-19 70.2 0.4 2.8 1 1 1 2 2 2 2 Transmembrane protein 231 Ferric_reduct PF01794.19 ORY40116.1 - 9.9e-16 58.0 9.7 9.9e-16 58.0 9.7 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ORY40116.1 - 1.1e-07 31.9 0.0 2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain ABC_membrane PF00664.23 ORY40118.1 - 2.5e-45 155.2 25.6 3e-27 96.0 14.5 4.2 2 2 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 ORY40118.1 - 2.1e-34 119.0 0.0 4e-26 92.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY40118.1 - 3.6e-08 33.1 0.5 1.1e-05 25.0 0.0 2.9 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY40118.1 - 0.052 13.6 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 ORY40118.1 - 0.12 12.4 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_29 PF13555.6 ORY40118.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 ORY40118.1 - 0.17 11.6 1.0 0.52 10.0 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AA_permease_2 PF13520.6 ORY40120.1 - 0.00011 21.1 27.2 0.00023 20.1 27.2 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY40120.1 - 0.011 14.4 19.3 0.013 14.1 19.3 1.1 1 0 0 1 1 1 0 Amino acid permease Peroxidase_2 PF01328.17 ORY40122.1 - 1e-28 101.2 0.0 1.3e-28 100.8 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 An_peroxidase PF03098.15 ORY40123.1 - 2.2e-90 303.7 0.0 2.9e-64 217.6 0.1 2.0 1 1 1 2 2 2 2 Animal haem peroxidase bZIP_1 PF00170.21 ORY40124.1 - 2e-05 24.6 1.0 3.2e-05 23.9 1.0 1.2 1 0 0 1 1 1 1 bZIP transcription factor DUF1769 PF08588.10 ORY40125.1 - 1.1e-19 70.4 0.2 2e-19 69.6 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) bZIP_2 PF07716.15 ORY40125.1 - 0.0029 17.7 7.4 0.0029 17.7 7.4 2.5 2 0 0 2 2 2 1 Basic region leucine zipper TFIIA PF03153.13 ORY40125.1 - 0.0061 16.6 33.2 0.0087 16.1 33.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit bZIP_1 PF00170.21 ORY40125.1 - 0.18 11.9 8.7 0.56 10.3 8.7 1.8 1 0 0 1 1 1 0 bZIP transcription factor DUF4600 PF15372.6 ORY40126.1 - 0.044 14.2 3.5 0.057 13.8 3.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) Ccdc124 PF06244.12 ORY40127.1 - 2.8e-32 112.0 0.2 5e-32 111.2 0.2 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 HMG_box PF00505.19 ORY40127.1 - 2.3e-05 24.7 0.8 4e-05 23.9 0.8 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box CHDNT PF08073.12 ORY40127.1 - 0.004 17.1 0.3 0.0066 16.4 0.3 1.4 1 0 0 1 1 1 1 CHDNT (NUC034) domain BAG PF02179.16 ORY40128.1 - 9.1e-11 42.0 0.1 9.1e-11 42.0 0.1 2.8 2 2 0 2 2 2 1 BAG domain FUSC PF04632.12 ORY40128.1 - 2.7 6.4 4.1 3.7 6.0 4.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family THOC7 PF05615.13 ORY40128.1 - 3.7 7.8 18.0 12 6.1 9.4 3.2 3 1 0 3 3 3 0 Tho complex subunit 7 7tm_1 PF00001.21 ORY40129.1 - 3.5e-07 29.8 14.2 4.4e-07 29.5 14.2 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SieB PF14163.6 ORY40130.1 - 0.13 11.7 0.3 0.86 9.1 0.3 2.1 1 1 0 1 1 1 0 Super-infection exclusion protein B Herpes_UL79 PF03049.14 ORY40130.1 - 0.2 11.3 1.3 0.25 10.9 0.6 1.5 1 1 0 1 1 1 0 UL79 family 7tm_1 PF00001.21 ORY40131.1 - 0.0037 16.6 9.7 0.01 15.2 9.7 1.8 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pmp3 PF01679.17 ORY40131.1 - 0.055 13.7 2.4 0.055 13.7 2.4 3.0 3 0 0 3 3 3 0 Proteolipid membrane potential modulator Abhydrolase_1 PF00561.20 ORY40132.1 - 1.1e-12 48.2 0.1 2.6e-08 33.8 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY40132.1 - 3.1e-12 46.3 0.0 2.5e-08 33.5 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY40132.1 - 6.4e-08 33.5 0.0 1e-07 32.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 ORY40132.1 - 0.0089 15.7 0.0 0.094 12.4 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 ORY40132.1 - 0.12 12.1 0.0 5.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 ORY40132.1 - 0.22 11.1 0.0 0.66 9.5 0.0 1.7 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) NOC3p PF07540.11 ORY40133.1 - 3.1e-29 101.3 0.0 3.1e-29 101.3 0.0 3.0 3 0 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.17 ORY40133.1 - 5e-15 56.0 0.5 5e-15 56.0 0.5 2.5 2 1 0 2 2 2 1 CBF/Mak21 family DUF4250 PF14056.6 ORY40133.1 - 0.037 14.0 1.7 5 7.2 0.6 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) SWIRM-assoc_2 PF16496.5 ORY40133.1 - 0.72 8.7 14.2 1.2 7.9 14.2 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DUF4407 PF14362.6 ORY40133.1 - 0.84 8.9 4.0 1.7 8.0 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4337 PF14235.6 ORY40133.1 - 2.6 8.1 7.6 5.6 7.0 7.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Rtf2 PF04641.12 ORY40133.1 - 5.2 6.4 13.7 5.6 6.2 12.4 1.7 2 0 0 2 2 2 0 Rtf2 RING-finger DUF4207 PF13904.6 ORY40134.1 - 0.78 9.4 39.1 4.9 6.8 9.5 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4207) DUF2852 PF11014.8 ORY40134.1 - 0.83 9.8 8.9 3.3 7.9 8.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2852) AAA_11 PF13086.6 ORY40134.1 - 1.1 8.9 12.0 2.3 8.0 12.0 1.5 1 0 0 1 1 1 0 AAA domain ELO PF01151.18 ORY40135.1 - 9.9e-59 198.9 17.1 1.2e-58 198.6 17.1 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family AA_permease_2 PF13520.6 ORY40137.1 - 0.00025 20.0 10.1 0.00034 19.6 10.1 1.2 1 0 0 1 1 1 1 Amino acid permease Pox_A14 PF05767.12 ORY40137.1 - 0.014 15.5 0.3 0.037 14.2 0.3 1.6 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Ribul_P_3_epim PF00834.19 ORY40138.1 - 4.3e-71 238.4 0.5 4.9e-71 238.2 0.5 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family His_biosynth PF00977.21 ORY40138.1 - 0.0038 16.7 0.0 0.015 14.8 0.0 2.0 2 1 1 3 3 3 1 Histidine biosynthesis protein OMPdecase PF00215.24 ORY40138.1 - 0.064 12.8 1.6 4.6 6.8 0.1 2.3 2 1 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family His_Phos_1 PF00300.22 ORY40139.1 - 5.4e-22 78.4 0.1 9.7e-22 77.6 0.1 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) YgaB PF14182.6 ORY40139.1 - 0.04 14.3 0.7 1.2 9.6 0.2 2.4 2 0 0 2 2 2 0 YgaB-like protein Thg1 PF04446.12 ORY40140.1 - 3.4e-27 95.0 0.0 6.1e-27 94.1 0.0 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase ABC_tran PF00005.27 ORY40141.1 - 6.5e-23 81.8 0.0 6.3e-13 49.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORY40141.1 - 6.9e-12 45.6 17.9 8.2e-06 25.7 5.3 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY40142.1 - 5.8e-58 195.3 0.5 1.7e-33 116.0 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORY40142.1 - 1.8e-46 159.0 40.6 7.4e-28 98.0 20.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ORY40142.1 - 1e-10 41.5 4.6 0.0022 17.5 0.3 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY40142.1 - 1.2e-08 35.5 0.1 0.001 19.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 ORY40142.1 - 1.5e-07 31.5 1.5 0.2 11.4 0.0 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY40142.1 - 2e-07 30.7 7.2 0.00097 18.8 0.0 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY40142.1 - 1.3e-06 28.5 0.3 0.039 14.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.9 ORY40142.1 - 5.2e-06 25.6 1.1 0.011 14.6 0.1 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 ORY40142.1 - 1.5e-05 25.3 5.5 0.011 15.9 0.1 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_22 PF13401.6 ORY40142.1 - 3.9e-05 23.9 0.3 0.42 10.9 0.0 3.3 3 1 0 3 3 2 2 AAA domain AAA_23 PF13476.6 ORY40142.1 - 8e-05 23.2 0.2 0.38 11.2 0.1 2.3 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 ORY40142.1 - 0.00016 20.8 0.5 0.48 9.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein RsgA_GTPase PF03193.16 ORY40142.1 - 0.00034 20.6 2.3 0.074 13.0 0.2 3.0 3 0 0 3 3 3 1 RsgA GTPase NACHT PF05729.12 ORY40142.1 - 0.00037 20.4 1.0 0.64 9.9 0.3 2.9 2 0 0 2 2 2 2 NACHT domain FtsK_SpoIIIE PF01580.18 ORY40142.1 - 0.0004 19.8 0.7 0.16 11.3 0.1 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_30 PF13604.6 ORY40142.1 - 0.00047 19.9 3.5 0.32 10.7 0.5 2.8 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 ORY40142.1 - 0.00051 19.4 1.9 0.096 12.0 0.6 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 ORY40142.1 - 0.00068 19.3 0.5 0.072 12.7 0.2 2.7 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 ORY40142.1 - 0.0012 18.9 2.7 0.088 12.9 0.6 2.5 2 0 0 2 2 2 1 Dynamin family AAA_7 PF12775.7 ORY40142.1 - 0.0015 18.0 0.2 1.2 8.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region cobW PF02492.19 ORY40142.1 - 0.0049 16.5 0.2 0.73 9.4 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 ORY40142.1 - 0.008 15.2 1.3 1.2 8.1 0.0 2.2 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RNA_helicase PF00910.22 ORY40142.1 - 0.013 15.9 0.1 7.6 7.0 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Ploopntkinase3 PF18751.1 ORY40142.1 - 0.017 15.1 0.3 2.3 8.1 0.1 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 ATP-synt_ab PF00006.25 ORY40142.1 - 0.022 14.4 0.4 2.2 7.9 0.1 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.17 ORY40142.1 - 0.025 14.4 1.4 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Roc PF08477.13 ORY40142.1 - 0.05 13.8 0.9 11 6.3 0.1 2.7 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 ORY40142.1 - 0.063 12.5 2.5 0.95 8.6 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.6 ORY40142.1 - 0.073 12.8 0.2 5.9 6.5 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 ORY40142.1 - 0.082 13.1 1.6 5.9 7.1 0.4 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ORY40142.1 - 0.086 12.6 0.2 1.7 8.4 0.1 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein ATPase PF06745.13 ORY40142.1 - 0.22 10.9 0.9 5.2 6.3 0.1 2.3 2 0 0 2 2 2 0 KaiC AAA_18 PF13238.6 ORY40142.1 - 0.34 11.5 1.0 16 6.1 0.2 2.7 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 ORY40142.1 - 0.53 10.0 3.3 14 5.4 1.0 3.0 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_28 PF13521.6 ORY40142.1 - 0.53 10.5 2.2 1.1 9.5 0.7 2.1 2 0 0 2 2 2 0 AAA domain CDH-cyt PF16010.5 ORY40143.1 - 4.3e-06 26.5 0.1 0.0039 16.9 0.0 3.4 2 2 0 2 2 2 2 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 ORY40143.1 - 0.00061 19.9 9.0 0.01 16.0 9.0 2.3 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 Ferric_reduct PF01794.19 ORY40143.1 - 0.0084 16.2 3.0 4.1 7.6 0.0 2.6 2 0 0 2 2 2 2 Ferric reductase like transmembrane component DOMON PF03351.17 ORY40143.1 - 0.061 13.5 2.3 0.076 13.2 0.0 2.3 3 0 0 3 3 3 0 DOMON domain CDH-cyt PF16010.5 ORY40144.1 - 1.1e-12 48.0 1.4 9.3e-12 45.0 0.1 2.7 2 1 1 3 3 3 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 ORY40144.1 - 8e-05 22.8 5.2 0.0003 20.9 5.3 1.8 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 ORY40144.1 - 2.6 7.9 6.3 24 4.8 6.3 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF2427) Actin PF00022.19 ORY40145.1 - 5.3e-16 58.2 0.0 6.5e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 Actin Herpes_pp85 PF04637.12 ORY40146.1 - 0.38 9.1 1.4 0.47 8.8 1.4 1.1 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) CDH-cyt PF16010.5 ORY40147.1 - 0.00055 19.7 0.6 0.003 17.3 0.0 1.9 1 1 1 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase zf-H2C2_5 PF13909.6 ORY40147.1 - 0.14 12.0 2.3 0.25 11.1 2.3 1.5 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Cytochrom_B561 PF03188.16 ORY40149.1 - 4.4e-07 30.1 3.0 4.4e-07 30.1 3.0 2.4 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 CDH-cyt PF16010.5 ORY40149.1 - 0.0043 16.7 0.0 0.0065 16.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF4051 PF13260.6 ORY40149.1 - 4.8 7.0 11.8 0.15 11.8 2.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4051) DUF2427 PF10348.9 ORY40149.1 - 8.9 6.2 13.7 3.5 7.5 0.3 4.0 3 1 2 5 5 5 0 Domain of unknown function (DUF2427) DUF2967 PF11179.8 ORY40150.1 - 0.11 10.6 10.3 0.12 10.4 10.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) ABC_membrane PF00664.23 ORY40151.1 - 6.3e-45 153.9 51.5 2.4e-31 109.4 22.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY40151.1 - 1.6e-39 135.6 0.0 3.1e-32 112.0 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY40151.1 - 1.9e-08 34.0 1.0 3.5e-05 23.3 0.8 3.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY40151.1 - 4.9e-06 26.2 0.1 1.4e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 ORY40151.1 - 2e-05 24.5 0.2 0.0052 16.6 0.0 3.0 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ORY40151.1 - 0.0095 16.4 0.0 0.026 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY40151.1 - 0.014 15.7 0.1 0.43 10.9 0.1 2.9 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ORY40151.1 - 0.02 15.0 0.0 0.052 13.6 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 ORY40151.1 - 0.028 14.5 0.1 0.058 13.5 0.1 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain Zeta_toxin PF06414.12 ORY40151.1 - 0.048 12.9 0.5 0.22 10.7 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin MID_MedPIWI PF18296.1 ORY40152.1 - 0.087 12.6 3.7 0.11 12.3 3.7 1.1 1 0 0 1 1 1 0 MID domain of medPIWI DUF3446 PF11928.8 ORY40153.1 - 0.001 19.3 8.6 0.001 19.3 8.6 6.7 4 2 1 5 5 5 1 Early growth response N-terminal domain Macoilin PF09726.9 ORY40153.1 - 3.8 5.9 6.0 1.1 7.7 2.0 1.8 2 0 0 2 2 2 0 Macoilin family NDUF_B12 PF08122.12 ORY40154.1 - 3.4e-13 49.4 3.3 3.4e-13 49.4 3.3 1.5 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase B12 subunit family MORN PF02493.20 ORY40155.1 - 3.8e-28 95.7 37.4 4.4e-05 23.1 0.1 7.3 7 0 0 7 7 7 7 MORN repeat DUF2158 PF09926.9 ORY40155.1 - 0.088 12.6 0.5 5.3 6.9 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized small protein (DUF2158) DUF3048_C PF17479.2 ORY40155.1 - 0.23 11.8 13.6 14 6.1 0.4 4.4 2 2 1 4 4 4 0 Protein of unknown function (DUF3048) C-terminal domain ALG3 PF05208.13 ORY40156.1 - 4e-133 444.3 25.0 4e-133 444.3 25.0 1.6 2 0 0 2 2 2 1 ALG3 protein cNMP_binding PF00027.29 ORY40158.1 - 3.8e-16 58.9 0.0 8.6e-16 57.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain NOD PF06816.13 ORY40158.1 - 0.14 11.8 0.1 0.68 9.6 0.0 2.1 1 1 1 2 2 2 0 NOTCH protein Thiamine_BP PF01910.17 ORY40159.1 - 0.026 14.5 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 Thiamine-binding protein Brucella_OMP2 PF05244.11 ORY40159.1 - 0.17 11.3 0.0 0.22 10.9 0.0 1.1 1 0 0 1 1 1 0 Brucella outer membrane protein 2 RhoGAP PF00620.27 ORY40160.1 - 3.2e-08 33.5 0.1 4e-08 33.2 0.1 1.1 1 0 0 1 1 1 1 RhoGAP domain DUF4111 PF13427.6 ORY40160.1 - 0.019 15.1 0.0 0.025 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) RhoGAP PF00620.27 ORY40161.1 - 9.7e-07 28.7 0.0 1.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain ABC1 PF03109.16 ORY40164.1 - 3.2e-16 59.6 0.0 8.4e-16 58.2 0.0 1.8 1 1 1 2 2 2 1 ABC1 family PT-VENN PF04829.13 ORY40164.1 - 0.014 15.4 1.5 0.044 13.9 1.5 1.8 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Pex14_N PF04695.13 ORY40164.1 - 0.21 12.3 4.2 0.068 13.8 1.3 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ABC_tran PF00005.27 ORY40165.1 - 7.1e-26 91.4 0.1 1.3e-25 90.5 0.1 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ORY40165.1 - 1.3e-11 44.7 0.2 9.8e-07 28.7 0.0 2.2 1 1 1 2 2 2 2 ABC transporter transmembrane region AAA_29 PF13555.6 ORY40165.1 - 0.00011 21.9 0.1 0.00025 20.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.14 ORY40165.1 - 0.008 16.2 0.1 12 5.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF87 PF01935.17 ORY40165.1 - 0.0085 16.2 0.8 0.016 15.3 0.2 1.7 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 ORY40165.1 - 0.012 16.0 0.1 0.022 15.1 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 ORY40165.1 - 0.02 15.0 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 ORY40165.1 - 0.021 15.1 0.1 0.077 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 ORY40165.1 - 0.024 14.5 0.5 0.36 10.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 ORY40165.1 - 0.039 13.7 0.3 0.22 11.2 0.3 2.1 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 ORY40165.1 - 0.045 13.2 0.6 0.3 10.5 0.1 2.1 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 ORY40165.1 - 0.079 12.0 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 ORY40165.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AFG1_ATPase PF03969.16 ORY40165.1 - 0.17 10.7 0.0 0.52 9.1 0.0 1.7 2 0 0 2 2 2 0 AFG1-like ATPase NB-ARC PF00931.22 ORY40165.1 - 0.17 11.0 0.4 0.4 9.8 0.2 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 ORY40165.1 - 0.2 12.2 0.1 0.43 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ORY40166.1 - 3.7e-21 76.1 0.0 6.9e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ORY40166.1 - 1.9e-17 63.8 9.8 3e-17 63.2 9.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ORY40166.1 - 0.0003 20.3 0.1 0.086 12.3 0.0 2.3 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY40166.1 - 0.00047 20.6 0.0 0.0011 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 ORY40166.1 - 0.0051 16.7 0.0 0.085 12.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY40166.1 - 0.0088 15.8 0.2 0.022 14.5 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ORY40166.1 - 0.011 15.3 0.3 0.026 14.1 0.3 1.5 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ORY40166.1 - 0.012 15.7 0.2 0.028 14.5 0.2 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 ORY40166.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 ORY40166.1 - 0.015 15.2 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain TrwB_AAD_bind PF10412.9 ORY40166.1 - 0.02 13.8 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain RsgA_GTPase PF03193.16 ORY40166.1 - 0.024 14.5 0.2 0.057 13.3 0.1 1.6 2 0 0 2 2 1 0 RsgA GTPase AAA_23 PF13476.6 ORY40166.1 - 0.031 14.8 0.1 0.058 13.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 ORY40166.1 - 0.038 13.1 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 ORY40166.1 - 0.043 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ORY40166.1 - 0.043 13.5 0.1 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Dynamin_N PF00350.23 ORY40166.1 - 0.046 13.8 0.2 0.086 12.9 0.2 1.4 1 0 0 1 1 1 0 Dynamin family AAA_28 PF13521.6 ORY40166.1 - 0.054 13.7 0.4 0.11 12.8 0.4 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 ORY40166.1 - 0.072 12.4 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF87 PF01935.17 ORY40166.1 - 0.074 13.1 3.1 0.061 13.4 1.4 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_30 PF13604.6 ORY40166.1 - 0.093 12.4 0.2 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 AAA domain Kinocilin PF15033.6 ORY40166.1 - 0.12 12.0 0.2 0.32 10.6 0.2 1.7 1 0 0 1 1 1 0 Kinocilin protein EMC1_C PF07774.13 ORY40167.1 - 6.3e-63 212.3 1.6 7.2e-63 212.1 0.1 1.9 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 ORY40167.1 - 2.8e-07 30.4 1.5 0.0099 15.5 0.5 3.9 3 1 1 4 4 4 3 PQQ-like domain ABC_tran PF00005.27 ORY40168.1 - 3.5e-31 108.5 0.0 4.9e-20 72.4 0.0 3.0 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORY40168.1 - 2e-11 44.1 2.1 2e-11 44.1 2.1 2.5 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.19 ORY40168.1 - 4.1e-06 26.4 4.2 0.038 13.4 1.4 3.3 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY40168.1 - 0.0043 17.4 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 ORY40168.1 - 0.014 15.0 0.2 0.08 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ORY40168.1 - 0.049 13.7 0.1 0.14 12.3 0.1 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY40168.1 - 0.051 13.3 0.3 0.15 11.9 0.3 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY40168.1 - 0.081 12.8 1.3 0.11 12.4 0.2 1.7 2 0 0 2 2 2 0 RsgA GTPase NACHT PF05729.12 ORY40168.1 - 0.089 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.18 ORY40168.1 - 0.12 11.7 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 ORY40168.1 - 0.35 11.4 0.0 0.35 11.4 0.0 2.4 3 0 0 3 3 2 0 AAA domain Dynamin_N PF00350.23 ORY40168.1 - 1.9 8.5 4.3 0.64 10.1 0.8 2.0 2 0 0 2 2 2 0 Dynamin family CDH-cyt PF16010.5 ORY40170.1 - 2e-16 60.2 6.6 3.1e-09 36.8 0.2 3.1 1 1 1 2 2 2 2 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 ORY40170.1 - 0.00032 20.9 10.7 0.046 13.9 0.1 3.1 2 1 1 3 3 3 2 DOMON domain Cytochrom_B561 PF03188.16 ORY40170.1 - 0.00052 20.2 4.3 0.00052 20.2 4.3 1.9 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Fungal_trans PF04082.18 ORY40171.1 - 0.011 14.8 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain SPRY PF00622.28 ORY40172.1 - 5.4e-09 36.2 0.0 0.25 11.5 0.0 4.3 3 1 1 4 4 4 3 SPRY domain F-box-like PF12937.7 ORY40172.1 - 0.0017 18.2 0.4 0.0045 16.8 0.2 1.9 2 0 0 2 2 2 1 F-box-like F-box_4 PF15966.5 ORY40172.1 - 0.0044 16.9 0.0 0.0082 16.0 0.0 1.3 1 0 0 1 1 1 1 F-box F-box PF00646.33 ORY40172.1 - 0.097 12.6 0.0 0.33 10.9 0.0 1.9 1 0 0 1 1 1 0 F-box domain CDH-cyt PF16010.5 ORY40173.1 - 7.6e-08 32.2 3.4 5.1e-07 29.6 0.8 2.7 2 1 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 ORY40173.1 - 1.3e-06 28.6 4.3 1.4e-06 28.5 2.3 2.2 2 1 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.17 ORY40173.1 - 1.4e-06 28.5 0.2 3.7e-06 27.2 0.2 1.7 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 ORY40173.1 - 2.6e-05 24.0 3.9 0.0002 21.1 4.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF2427) PseudoU_synth_2 PF00849.22 ORY40176.1 - 8e-27 94.3 0.0 9.5e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 RNA pseudouridylate synthase TauD PF02668.16 ORY40177.1 - 1.7e-39 136.2 0.2 2.7e-39 135.6 0.2 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family OPT PF03169.15 ORY40178.1 - 5.6e-117 391.9 53.8 8.7e-117 391.3 53.8 1.3 1 1 0 1 1 1 1 OPT oligopeptide transporter protein Ax_dynein_light PF10211.9 ORY40179.1 - 2.1e-05 24.6 9.0 2.1e-05 24.6 9.0 4.0 3 1 3 6 6 6 1 Axonemal dynein light chain P22_AR_N PF10547.9 ORY40179.1 - 0.039 14.3 1.9 4.5 7.6 0.0 3.4 3 0 0 3 3 3 0 P22_AR N-terminal domain Hs1pro-1_C PF07014.12 ORY40179.1 - 0.21 11.0 0.0 0.21 11.0 0.0 3.5 3 1 2 5 5 5 0 Hs1pro-1 protein C-terminus zf-C2HC_2 PF13913.6 ORY40180.1 - 1.3e-07 31.4 0.9 1.3e-07 31.4 0.9 2.2 2 1 0 2 2 2 1 zinc-finger of a C2HC-type zf-CpG_bind_C PF12269.8 ORY40180.1 - 0.01 15.7 0.5 0.4 10.4 0.1 2.4 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain zf-C2H2 PF00096.26 ORY40180.1 - 0.84 10.2 4.3 3.9 8.1 0.2 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY40180.1 - 8.1 7.6 6.9 2.2 9.3 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger ApoA-II PF04711.13 ORY40181.1 - 0.056 13.6 0.1 0.17 12.0 0.1 1.8 1 0 0 1 1 1 0 Apolipoprotein A-II (ApoA-II) TetR_C_22 PF17928.1 ORY40181.1 - 0.1 12.9 0.4 16 5.8 0.0 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain SET PF00856.28 ORY40182.1 - 4.2e-08 33.8 0.0 8.5e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 SET domain PNRC PF15365.6 ORY40183.1 - 8.1e-09 35.1 0.8 8.1e-09 35.1 0.8 3.2 3 0 0 3 3 3 1 Proline-rich nuclear receptor coactivator motif Elong_Iki1 PF10483.9 ORY40184.1 - 1.6e-11 44.2 0.0 4.1e-11 42.9 0.0 1.8 1 1 0 1 1 1 1 Elongator subunit Iki1 FA_hydroxylase PF04116.13 ORY40185.1 - 5.3e-05 23.6 16.1 5.3e-05 23.6 16.1 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily SCAMP PF04144.13 ORY40186.1 - 1.1e-46 159.4 6.3 1.3e-46 159.1 6.3 1.0 1 0 0 1 1 1 1 SCAMP family Pam16 PF03656.13 ORY40188.1 - 8.4e-31 106.6 0.6 9.8e-31 106.4 0.6 1.0 1 0 0 1 1 1 1 Pam16 DUF2802 PF10975.8 ORY40188.1 - 0.056 13.6 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) ABC_tran PF00005.27 ORY40189.1 - 4.3e-55 186.0 2.6 2.6e-32 112.2 0.1 2.9 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 ORY40189.1 - 2.6e-47 161.7 38.2 2.3e-29 102.9 18.4 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ORY40189.1 - 1.4e-11 44.3 6.4 6.2e-05 22.5 1.0 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY40189.1 - 3.8e-10 39.3 3.6 1.2e-05 24.9 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 ORY40189.1 - 1e-08 35.4 6.1 0.016 15.1 0.1 4.5 4 1 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 ORY40189.1 - 5.8e-07 29.6 0.9 0.046 13.8 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY40189.1 - 2e-06 28.3 0.3 0.094 13.1 0.1 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 ORY40189.1 - 3.1e-05 24.6 8.8 0.023 15.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 ORY40189.1 - 0.00027 20.9 0.2 0.24 11.3 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 ORY40189.1 - 0.00029 20.6 3.0 0.33 10.6 0.1 3.1 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 ORY40189.1 - 0.00029 20.2 3.1 0.2 10.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_7 PF12775.7 ORY40189.1 - 0.00038 20.0 0.8 0.89 9.0 0.1 2.9 3 0 0 3 3 3 2 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 ORY40189.1 - 0.00097 18.6 2.3 0.97 8.7 0.1 3.6 4 0 0 4 4 4 2 FtsK/SpoIIIE family T2SSE PF00437.20 ORY40189.1 - 0.0012 18.0 0.9 0.98 8.4 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF87 PF01935.17 ORY40189.1 - 0.0015 18.7 6.2 0.052 13.6 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_22 PF13401.6 ORY40189.1 - 0.0017 18.7 3.9 0.42 10.9 0.0 3.1 2 1 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 ORY40189.1 - 0.0058 16.6 0.7 2.5 7.9 0.2 2.5 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_25 PF13481.6 ORY40189.1 - 0.0062 16.1 0.1 0.61 9.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 ORY40189.1 - 0.0068 15.6 3.1 1.1 8.4 0.1 3.5 3 0 0 3 3 3 1 NB-ARC domain Roc PF08477.13 ORY40189.1 - 0.01 16.1 2.2 5.2 7.3 0.1 3.3 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase DUF815 PF05673.13 ORY40189.1 - 0.012 14.8 1.7 0.7 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MeaB PF03308.16 ORY40189.1 - 0.012 14.6 3.2 0.68 8.9 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 ORY40189.1 - 0.015 15.3 5.2 0.56 10.2 0.9 3.3 3 0 0 3 3 3 0 Dynamin family NACHT PF05729.12 ORY40189.1 - 0.022 14.7 3.8 5 7.0 0.1 3.1 3 0 0 3 3 3 0 NACHT domain TrwB_AAD_bind PF10412.9 ORY40189.1 - 0.024 13.5 6.6 0.98 8.3 0.2 2.8 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 ORY40189.1 - 0.029 14.0 0.3 9.6 5.7 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 ORY40189.1 - 0.063 13.1 3.5 1.8 8.3 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 ORY40189.1 - 0.063 13.7 0.3 8.3 6.9 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 ORY40189.1 - 0.22 12.0 1.7 18 5.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.6 ORY40189.1 - 0.28 10.9 1.7 1.6 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 ORY40189.1 - 0.62 9.7 7.5 3.2 7.4 0.1 3.1 3 0 0 3 3 3 0 AAA ATPase domain PRK PF00485.18 ORY40189.1 - 0.95 9.2 3.8 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.25 ORY40189.1 - 3.3 7.3 5.0 16 5.0 0.1 2.7 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SAGA-Tad1 PF12767.7 ORY40190.1 - 5.6e-31 108.1 3.2 7.4e-31 107.7 3.2 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit ABC_tran PF00005.27 ORY40191.1 - 2.9e-56 189.8 0.8 2.6e-32 112.2 0.1 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORY40191.1 - 1.2e-45 156.3 42.2 2.3e-26 93.1 16.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ORY40191.1 - 7.8e-12 45.1 7.4 6.2e-05 22.5 1.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ORY40191.1 - 2.1e-10 40.9 2.3 0.016 15.1 0.1 4.2 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY40191.1 - 2.7e-10 39.8 3.7 1.2e-05 24.9 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY40191.1 - 5.3e-07 29.7 2.7 0.024 14.7 0.2 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY40191.1 - 3.7e-06 27.4 1.2 0.11 12.9 0.2 3.3 2 1 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 ORY40191.1 - 0.0001 22.8 11.0 0.023 15.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 ORY40191.1 - 0.00023 21.1 0.1 0.22 11.4 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 ORY40191.1 - 0.00027 20.3 3.1 0.2 10.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.6 ORY40191.1 - 0.00044 20.5 2.4 0.42 10.9 0.0 3.4 3 1 0 3 3 2 1 AAA domain AAA_7 PF12775.7 ORY40191.1 - 0.00055 19.5 1.3 1.1 8.8 0.1 2.9 3 0 0 3 3 3 2 P-loop containing dynein motor region DUF87 PF01935.17 ORY40191.1 - 0.00095 19.3 7.4 0.052 13.6 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 ORY40191.1 - 0.0015 18.0 1.7 0.72 9.1 0.1 2.9 3 0 0 3 3 3 2 FtsK/SpoIIIE family Ploopntkinase3 PF18751.1 ORY40191.1 - 0.0051 16.7 0.7 2.1 8.2 0.2 2.5 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_25 PF13481.6 ORY40191.1 - 0.0056 16.3 0.1 0.5 9.9 0.0 2.7 3 0 0 3 3 2 1 AAA domain Roc PF08477.13 ORY40191.1 - 0.0061 16.8 1.8 5.2 7.3 0.1 3.3 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 ORY40191.1 - 0.0061 15.7 3.5 0.98 8.4 0.0 2.6 3 0 0 3 3 3 2 Type II/IV secretion system protein Na_Pi_cotrans PF02690.15 ORY40191.1 - 0.0076 16.4 0.2 0.0076 16.4 0.2 3.4 2 1 1 3 3 3 1 Na+/Pi-cotransporter AAA_30 PF13604.6 ORY40191.1 - 0.0079 15.9 8.0 0.5 10.1 0.6 3.2 4 0 0 4 4 4 2 AAA domain Dynamin_N PF00350.23 ORY40191.1 - 0.0088 16.1 5.3 0.23 11.5 1.0 3.1 3 0 0 3 3 3 1 Dynamin family NACHT PF05729.12 ORY40191.1 - 0.011 15.6 3.8 2.6 7.9 0.6 3.0 3 0 0 3 3 3 0 NACHT domain NB-ARC PF00931.22 ORY40191.1 - 0.014 14.6 2.4 1.1 8.4 0.1 2.8 2 0 0 2 2 2 0 NB-ARC domain DUF815 PF05673.13 ORY40191.1 - 0.018 14.2 2.0 0.7 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) MeaB PF03308.16 ORY40191.1 - 0.019 13.9 3.6 0.68 8.9 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TrwB_AAD_bind PF10412.9 ORY40191.1 - 0.02 13.8 6.6 0.74 8.7 0.3 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 ORY40191.1 - 0.02 14.5 0.3 7.7 6.1 0.1 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 ORY40191.1 - 0.031 14.6 0.2 8.3 6.9 0.0 2.9 3 0 0 3 3 2 0 RNA helicase ATP_bind_1 PF03029.17 ORY40191.1 - 0.071 12.9 3.1 1.8 8.3 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_ATPase PF09818.9 ORY40191.1 - 0.23 10.2 2.6 1.8 7.3 0.9 2.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class PRK PF00485.18 ORY40191.1 - 0.26 11.0 3.1 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.6 ORY40191.1 - 0.62 10.1 2.9 5.6 7.0 0.0 3.5 4 0 0 4 4 4 0 AAA domain AAA_24 PF13479.6 ORY40191.1 - 0.86 9.3 4.4 1.6 8.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 ORY40191.1 - 1.1 8.9 9.2 3.2 7.4 0.1 2.8 3 0 0 3 3 3 0 AAA ATPase domain MobB PF03205.14 ORY40191.1 - 1.3 8.9 3.6 16 5.4 0.0 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.25 ORY40191.1 - 3.2 7.4 5.9 16 5.0 0.1 2.6 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.6 ORY40191.1 - 4.5 7.8 6.2 18 5.9 0.0 3.1 4 0 0 4 4 2 0 AAA domain LRR_8 PF13855.6 ORY40192.1 - 3e-10 39.7 1.2 6.2e-06 25.9 0.5 3.8 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 ORY40192.1 - 4.8e-06 26.8 1.8 0.0043 17.4 0.6 3.6 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY40192.1 - 0.0073 16.7 1.9 38 5.4 0.1 4.3 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 ORY40192.1 - 0.028 14.4 4.9 11 6.4 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich repeat FANCI_S4 PF14678.6 ORY40192.1 - 0.068 12.3 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 FANCI solenoid 4 PUF PF00806.19 ORY40193.1 - 3e-65 212.4 13.5 1.7e-08 33.7 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat sCache_2 PF17200.4 ORY40193.1 - 0.0013 18.6 0.7 3.5 7.4 0.0 4.1 5 0 0 5 5 5 1 Single Cache domain 2 NABP PF07990.12 ORY40193.1 - 0.0066 16.0 0.7 0.013 15.0 0.0 1.8 2 0 0 2 2 2 1 Nucleic acid binding protein NABP Importin_rep_3 PF18806.1 ORY40193.1 - 0.039 14.0 0.5 0.81 9.8 0.0 3.4 3 2 0 3 3 3 0 Importin 13 repeat Ost5 PF05251.12 ORY40195.1 - 2.2e-11 43.9 0.6 2.5e-11 43.7 0.6 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 DHFR_1 PF00186.19 ORY40196.1 - 1.8e-27 96.0 0.0 8.9e-27 93.8 0.0 1.8 1 1 0 1 1 1 1 Dihydrofolate reductase Spc7 PF08317.11 ORY40197.1 - 5.1e-34 117.6 0.1 8.6e-34 116.8 0.1 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Proteasome PF00227.26 ORY40199.1 - 2.1e-50 170.9 0.0 2.5e-50 170.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Ion_trans PF00520.31 ORY40200.1 - 4.9e-38 130.8 31.1 7.2e-38 130.2 31.1 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 ORY40200.1 - 9.7e-09 34.4 12.2 9.7e-09 34.4 12.2 2.1 1 1 1 2 2 2 2 Polycystin cation channel DUF4834 PF16118.5 ORY40200.1 - 0.13 13.2 5.7 5.4 8.0 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Rx_N PF18052.1 ORY40200.1 - 0.69 10.2 3.3 0.48 10.7 0.8 2.0 2 0 0 2 2 2 0 Rx N-terminal domain zf-MIZ PF02891.20 ORY40203.1 - 6.3e-11 41.9 1.7 7.1e-11 41.7 0.2 1.8 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 ORY40203.1 - 0.0052 16.6 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Muted PF14942.6 ORY40205.1 - 0.00075 19.9 0.7 0.00075 19.9 0.7 3.9 3 1 1 4 4 4 2 Organelle biogenesis, Muted-like protein NPV_P10 PF05531.12 ORY40205.1 - 0.0039 17.6 15.4 2.2 8.8 0.2 4.6 2 2 1 3 3 3 1 Nucleopolyhedrovirus P10 protein SYCE1 PF15233.6 ORY40205.1 - 0.0058 16.7 10.5 0.0058 16.7 10.5 3.5 1 1 2 3 3 3 1 Synaptonemal complex central element protein 1 DUF4407 PF14362.6 ORY40205.1 - 0.0077 15.6 42.1 0.047 13.0 19.6 3.4 2 1 1 3 3 3 2 Domain of unknown function (DUF4407) HSBP1 PF06825.12 ORY40205.1 - 0.014 15.2 1.3 1.6 8.7 0.1 3.6 3 0 0 3 3 3 0 Heat shock factor binding protein 1 ABC_tran_CTD PF16326.5 ORY40205.1 - 0.021 15.1 0.9 0.021 15.1 0.9 7.3 2 2 4 6 6 5 0 ABC transporter C-terminal domain UPF0184 PF03670.13 ORY40205.1 - 0.024 15.0 3.4 0.031 14.6 0.1 2.9 2 2 1 3 3 3 0 Uncharacterised protein family (UPF0184) Filament PF00038.21 ORY40205.1 - 0.039 13.5 32.9 0.76 9.3 28.2 3.0 2 1 0 2 2 2 0 Intermediate filament protein Fez1 PF06818.15 ORY40205.1 - 0.087 13.3 34.3 0.032 14.7 13.0 3.1 2 1 1 3 3 3 0 Fez1 Spc7 PF08317.11 ORY40205.1 - 0.17 10.8 40.9 0.018 13.9 13.9 2.8 2 1 1 3 3 3 0 Spc7 kinetochore protein TolA_bind_tri PF16331.5 ORY40205.1 - 0.64 10.1 15.3 2.9 8.0 0.6 5.1 5 1 0 5 5 5 0 TolA binding protein trimerisation BLOC1_2 PF10046.9 ORY40205.1 - 0.96 9.8 23.5 0.6 10.5 6.6 4.3 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 OSTbeta PF15048.6 ORY40205.1 - 1.4 9.1 7.1 3.4 7.8 0.2 2.9 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein HOOK PF05622.12 ORY40205.1 - 1.6 6.8 34.4 1.4 6.9 4.2 3.2 2 1 2 4 4 4 0 HOOK protein Osmo_CC PF08946.10 ORY40205.1 - 2.5 8.4 14.8 20 5.5 0.2 5.8 5 2 0 5 5 5 0 Osmosensory transporter coiled coil Baculo_p24 PF05073.12 ORY40205.1 - 7.5 6.3 17.3 4.3 7.1 3.7 3.3 1 1 2 3 3 3 0 Baculovirus P24 capsid protein FAM76 PF16046.5 ORY40205.1 - 7.9 5.7 26.8 1.5 8.2 4.8 3.2 2 1 1 3 3 3 0 FAM76 protein DUF812 PF05667.11 ORY40205.1 - 9.4 5.0 39.1 0.46 9.3 15.3 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF812) RNase_P_Rpp14 PF01900.19 ORY40207.1 - 5.5e-27 94.0 0.1 6.7e-27 93.7 0.1 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family HrpB7 PF09486.10 ORY40208.1 - 0.004 17.6 7.7 0.0088 16.4 7.7 1.5 1 0 0 1 1 1 1 Bacterial type III secretion protein (HrpB7) Med4 PF10018.9 ORY40208.1 - 0.0066 16.2 1.5 0.015 14.9 0.6 2.0 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 DHR10 PF18595.1 ORY40208.1 - 0.0075 16.3 8.6 0.0075 16.3 8.6 1.9 2 0 0 2 2 2 1 Designed helical repeat protein 10 domain Spc7 PF08317.11 ORY40208.1 - 0.0093 14.9 2.9 0.017 14.0 2.9 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF2780 PF11075.8 ORY40208.1 - 0.012 15.8 0.4 0.012 15.8 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function VcgC/VcgE (DUF2780) CALCOCO1 PF07888.11 ORY40208.1 - 0.013 14.5 5.1 0.02 13.8 5.1 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like TMF_DNA_bd PF12329.8 ORY40208.1 - 0.052 13.6 0.8 0.15 12.0 0.2 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding PKcGMP_CC PF16808.5 ORY40208.1 - 0.052 13.4 0.6 0.12 12.3 0.6 1.6 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4201 PF13870.6 ORY40208.1 - 0.068 12.9 5.8 1.2 8.8 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF4763 PF15960.5 ORY40208.1 - 0.17 11.1 2.3 0.4 10.0 2.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) CENP-H PF05837.12 ORY40208.1 - 0.26 11.7 6.6 0.17 12.3 3.3 2.0 2 0 0 2 2 2 0 Centromere protein H (CENP-H) OmpH PF03938.14 ORY40208.1 - 0.31 11.4 6.2 0.085 13.2 2.6 1.8 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FUSC PF04632.12 ORY40208.1 - 0.54 8.7 3.4 0.79 8.2 3.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Taxilin PF09728.9 ORY40208.1 - 0.66 9.1 7.5 3.8 6.6 0.2 2.1 2 0 0 2 2 2 0 Myosin-like coiled-coil protein ADIP PF11559.8 ORY40208.1 - 1.2 9.2 9.4 12 6.0 0.2 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 ORY40208.1 - 4.1 7.9 11.6 0.4 11.2 6.4 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region Jnk-SapK_ap_N PF09744.9 ORY40208.1 - 5.7 7.1 8.4 1.2 9.3 3.3 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Pkinase PF00069.25 ORY40209.1 - 2e-70 237.2 0.0 2.7e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY40209.1 - 8.8e-50 169.4 0.0 1.3e-49 168.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 ORY40209.1 - 1.2e-22 80.0 0.0 2.5e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 ORY40209.1 - 7.1e-08 31.6 0.0 1.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY40209.1 - 3.6e-07 29.8 0.0 7e-07 28.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 ORY40209.1 - 0.0022 17.9 1.3 0.015 15.2 0.1 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family KIND PF16474.5 ORY40209.1 - 0.05 13.5 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Haspin_kinase PF12330.8 ORY40209.1 - 0.058 12.3 1.4 0.08 11.9 0.2 1.7 2 1 0 2 2 2 0 Haspin like kinase domain Kdo PF06293.14 ORY40209.1 - 0.15 11.4 0.1 0.3 10.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 ORY40209.1 - 0.16 11.0 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Synaptobrevin PF00957.21 ORY40210.1 - 1.3e-32 111.4 4.0 1.4e-32 111.3 4.0 1.0 1 0 0 1 1 1 1 Synaptobrevin GP41 PF00517.17 ORY40210.1 - 0.003 17.5 1.7 0.004 17.1 1.7 1.1 1 0 0 1 1 1 1 Retroviral envelope protein Pex24p PF06398.11 ORY40210.1 - 0.0097 14.9 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Baculo_F PF12259.8 ORY40210.1 - 0.013 14.1 0.3 0.015 13.9 0.3 1.0 1 0 0 1 1 1 0 Baculovirus F protein MCU PF04678.13 ORY40210.1 - 0.017 15.3 0.1 0.02 15.0 0.1 1.0 1 0 0 1 1 1 0 Mitochondrial calcium uniporter LRRC37AB_C PF14914.6 ORY40210.1 - 0.064 13.2 0.4 0.072 13.0 0.4 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF515 PF04415.12 ORY40210.1 - 0.088 11.2 5.1 0.065 11.6 4.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF515) ASFV_J13L PF05568.11 ORY40210.1 - 0.75 9.5 4.3 0.26 11.0 1.9 1.4 2 0 0 2 2 2 0 African swine fever virus J13L protein ODV-E18 PF10717.9 ORY40210.1 - 0.87 9.5 3.9 0.36 10.7 1.0 1.7 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Cupin_8 PF13621.6 ORY40211.1 - 4.5e-35 121.6 0.1 1.4e-34 120.0 0.0 1.8 2 0 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 ORY40211.1 - 0.015 14.8 0.0 0.72 9.3 0.0 2.5 2 0 0 2 2 2 0 Cupin superfamily protein JmjC PF02373.22 ORY40211.1 - 0.053 14.0 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 JmjC domain, hydroxylase KDZ PF18758.1 ORY40213.1 - 6.2e-17 62.0 0.1 7.7e-17 61.6 0.1 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF5113 PF17140.4 ORY40215.1 - 0.15 11.8 1.3 0.63 9.8 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) SEP PF08059.13 ORY40216.1 - 5.3e-17 62.1 0.0 9.8e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 SEP domain GST_N_3 PF13417.6 ORY40217.1 - 3.1e-06 27.5 0.0 5.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY40217.1 - 4.4e-05 23.4 0.2 7.6e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY40217.1 - 0.00037 20.7 0.1 0.0008 19.6 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY40217.1 - 0.023 15.0 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain CDC45 PF02724.14 ORY40218.1 - 1.3e-173 578.7 0.0 3.9e-173 577.2 0.0 1.7 1 1 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 ORY40218.1 - 1.7 8.0 16.9 0.058 12.8 10.6 1.7 2 0 0 2 2 2 0 SDA1 adh_short PF00106.25 ORY40219.1 - 6.6e-48 162.8 0.6 7.8e-48 162.5 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY40219.1 - 9.4e-37 126.8 0.0 1.3e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY40219.1 - 1.9e-06 27.9 0.1 2.9e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 ORY40219.1 - 0.00051 19.5 0.0 0.0024 17.3 0.0 1.8 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 ORY40219.1 - 0.0011 18.4 0.0 0.0015 18.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY40219.1 - 0.027 13.9 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase CLPTM1 PF05602.12 ORY40220.1 - 8.3e-140 466.6 1.2 1e-139 466.3 1.2 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 ORY40220.1 - 0.049 13.4 1.7 1.4 8.7 0.2 2.5 2 0 0 2 2 2 0 PQ loop repeat MtN3_slv PF03083.16 ORY40220.1 - 2.7 8.1 12.3 0.036 14.1 1.2 2.9 2 1 1 3 3 3 0 Sugar efflux transporter for intercellular exchange CDC45 PF02724.14 ORY40220.1 - 3 6.0 13.6 4.1 5.6 13.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4604 PF15377.6 ORY40220.1 - 6.3 7.2 28.9 3.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Fungal_trans PF04082.18 ORY40221.1 - 0.029 13.4 0.5 0.062 12.3 0.0 1.7 2 0 0 2 2 2 0 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY40221.1 - 0.46 10.6 21.8 1.4 9.1 7.0 2.6 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain LicD PF04991.13 ORY40222.1 - 1e-19 71.6 1.1 1.1e-15 58.4 0.7 2.5 1 1 1 2 2 2 2 LicD family SpvB PF03534.13 ORY40222.1 - 0.073 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Salmonella virulence plasmid 65kDa B protein LicD PF04991.13 ORY40223.1 - 1.2e-18 68.1 1.0 1.1e-14 55.1 0.3 2.3 1 1 1 2 2 2 2 LicD family LicD PF04991.13 ORY40224.1 - 1.3e-14 54.9 5.4 1.7e-11 44.7 1.1 3.1 3 1 1 4 4 4 2 LicD family Peptidase_S10 PF00450.22 ORY40225.1 - 8.5e-89 298.8 0.3 1.1e-88 298.5 0.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF2205 PF10224.9 ORY40226.1 - 6.5e-13 48.5 0.0 1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Short coiled-coil protein Sas10_Utp3 PF04000.15 ORY40226.1 - 0.034 14.8 0.1 0.06 14.0 0.1 1.4 1 0 0 1 1 1 0 Sas10/Utp3/C1D family Tudor_2 PF18104.1 ORY40227.1 - 0.0078 15.9 2.1 0.0084 15.8 0.1 2.1 2 1 0 2 2 2 1 Jumonji domain-containing protein 2A Tudor domain LHC PF00556.20 ORY40229.1 - 7.3 6.9 6.0 17 5.8 6.0 1.6 1 0 0 1 1 1 0 Antenna complex alpha/beta subunit ANAPC4_WD40 PF12894.7 ORY40233.1 - 8.5e-06 26.0 1.0 0.022 15.1 0.6 3.6 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY40233.1 - 0.00022 21.9 0.7 9.2 7.3 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Multi_Drug_Res PF00893.19 ORY40235.1 - 0.1 13.3 1.1 0.17 12.6 0.2 1.8 2 0 0 2 2 2 0 Small Multidrug Resistance protein zf-MYND PF01753.18 ORY40236.1 - 2.1e-08 34.1 10.6 2.8e-08 33.7 10.6 1.2 1 0 0 1 1 1 1 MYND finger DEAD PF00270.29 ORY40237.1 - 1.5e-46 158.4 0.0 3.7e-46 157.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY40237.1 - 3.3e-25 88.6 0.1 9.4e-25 87.1 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY40237.1 - 0.00014 22.0 0.0 0.00034 20.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 ORY40237.1 - 0.12 11.1 0.0 0.31 9.7 0.0 1.6 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 FISNA PF14484.6 ORY40237.1 - 1.2 9.4 4.5 0.65 10.3 0.4 2.4 3 0 0 3 3 3 0 Fish-specific NACHT associated domain 7tm_3 PF00003.22 ORY40238.1 - 2.6e-09 37.1 12.2 4.1e-09 36.5 12.2 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 ORY40239.1 - 1.8e-17 63.5 0.0 2.5e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY40239.1 - 4e-05 23.5 0.0 4.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein TPP_enzyme_M PF00205.22 ORY40239.1 - 0.0029 17.4 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Methyltransf_25 PF13649.6 ORY40241.1 - 4.8e-12 46.4 0.0 2e-11 44.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY40241.1 - 4.2e-10 39.7 0.0 8.4e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY40241.1 - 8.7e-10 39.1 0.0 2e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY40241.1 - 3.1e-09 36.8 0.0 5.3e-08 32.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY40241.1 - 9.1e-06 26.3 0.0 0.00013 22.7 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 ORY40241.1 - 0.00054 19.6 0.0 0.0019 17.8 0.0 1.7 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_29 PF03141.16 ORY40241.1 - 0.0024 16.5 0.0 0.0042 15.7 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase FtsJ PF01728.19 ORY40241.1 - 0.016 15.3 0.2 0.034 14.3 0.2 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 ORY40242.1 - 1.2e-09 38.7 0.0 2.8e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY40242.1 - 3.4e-09 36.7 0.0 8.1e-09 35.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY40242.1 - 9.2e-09 35.8 0.0 2.3e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY40242.1 - 9.6e-09 35.3 0.0 1.3e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 ORY40242.1 - 0.07 13.2 0.0 0.11 12.6 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 ORY40242.1 - 0.087 13.6 0.0 0.27 12.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain WD40 PF00400.32 ORY40243.1 - 0.05 14.5 0.0 0.77 10.7 0.0 2.1 2 0 0 2 2 2 0 WD domain, G-beta repeat PhoLip_ATPase_C PF16212.5 ORY40244.1 - 5.8e-73 245.7 26.5 5.8e-73 245.7 26.5 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY40244.1 - 8.3e-21 73.5 0.6 2.7e-20 71.8 0.6 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 ORY40244.1 - 2.3e-12 46.8 0.0 8.9e-12 44.9 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY40244.1 - 1.2e-08 35.5 0.1 0.011 16.1 0.0 3.5 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORY40244.1 - 2.5e-07 30.4 0.0 7.2e-06 25.6 0.0 3.0 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 ORY40244.1 - 0.0019 18.0 0.2 0.0057 16.4 0.2 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase TRAPPC9-Trs120 PF08626.11 ORY40245.1 - 2.6e-157 525.3 0.0 2.6e-73 247.1 0.0 3.5 3 1 0 3 3 3 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Peptidase_S10 PF00450.22 ORY40246.1 - 6.7e-88 295.9 0.7 8e-88 295.6 0.7 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.22 ORY40247.1 - 6.8e-87 292.6 1.2 9e-87 292.2 1.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase SSP160 PF06933.11 ORY40249.1 - 0.008 14.4 7.4 0.011 14.0 7.4 1.2 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 AF-4 PF05110.13 ORY40249.1 - 0.24 9.5 8.2 0.29 9.2 8.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Mg_trans_NIPA PF05653.14 ORY40251.1 - 6.3e-91 304.5 18.3 8.1e-91 304.2 18.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORY40251.1 - 2.2e-05 24.6 3.1 2.2e-05 24.6 3.1 3.8 3 1 0 3 3 3 2 EamA-like transporter family Ninjurin PF04923.12 ORY40251.1 - 0.018 15.0 1.6 0.39 10.7 0.7 2.8 3 0 0 3 3 3 0 Ninjurin TMEM72 PF16054.5 ORY40251.1 - 2.8 7.6 9.5 0.51 10.0 4.1 2.1 2 0 0 2 2 2 0 Transmembrane protein family 72 TIR_2 PF13676.6 ORY40252.1 - 7.6e-11 42.7 0.0 1.4e-10 41.8 0.0 1.4 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 ORY40252.1 - 0.00046 20.0 0.0 0.00088 19.1 0.0 1.5 1 0 0 1 1 1 1 TIR domain CHORD PF04968.12 ORY40252.1 - 0.016 15.9 1.5 0.03 15.0 1.2 1.6 1 1 0 1 1 1 0 CHORD Glyco_hydro_18 PF00704.28 ORY40253.1 - 4.8e-66 223.6 0.0 5.9e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Pro_isomerase PF00160.21 ORY40254.1 - 3e-49 167.3 0.6 4.4e-49 166.8 0.6 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.28 ORY40254.1 - 1.1e-07 31.3 4.0 4.2e-05 23.2 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY40254.1 - 7.4e-07 28.8 4.4 0.0059 16.6 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY40254.1 - 3e-05 23.9 2.7 0.001 19.1 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY40254.1 - 0.00045 19.8 5.8 0.31 10.7 1.3 2.6 2 0 0 2 2 2 2 TPR repeat TPR_14 PF13428.6 ORY40254.1 - 0.0021 18.7 2.3 0.058 14.2 0.5 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY40254.1 - 0.0036 17.2 0.6 0.33 11.1 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 ORY40254.1 - 0.0052 16.8 6.4 0.14 12.2 0.5 2.5 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 ORY40254.1 - 0.016 15.8 3.4 1.8 9.3 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY40254.1 - 0.021 15.1 2.0 4.3 7.7 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 ORY40254.1 - 0.077 13.4 1.0 0.15 12.5 0.2 1.8 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_9 PF13371.6 ORY40254.1 - 0.13 12.4 1.0 0.51 10.5 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Ctr PF04145.15 ORY40256.1 - 9.1e-10 39.3 4.6 8.7e-09 36.2 4.6 2.1 1 1 0 1 1 1 1 Ctr copper transporter family DUF3429 PF11911.8 ORY40259.1 - 6.6e-30 104.3 11.4 7.8e-30 104.1 11.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Spem1 PF15670.5 ORY40260.1 - 0.11 12.1 11.7 0.14 11.7 11.7 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 Helo_like_N PF17111.5 ORY40260.1 - 0.24 10.7 4.6 0.081 12.3 1.7 1.7 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Presenilin PF01080.17 ORY40260.1 - 1.8 7.3 2.6 1.9 7.1 2.6 1.0 1 0 0 1 1 1 0 Presenilin DUF2407_C PF13373.6 ORY40260.1 - 2.9 8.1 4.7 4.6 7.4 4.7 1.3 1 1 0 1 1 1 0 DUF2407 C-terminal domain Zip PF02535.22 ORY40260.1 - 4.9 6.3 5.4 5.5 6.1 5.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Sulfotransfer_3 PF13469.6 ORY40261.1 - 4.5e-28 99.1 0.0 3.5e-27 96.2 0.0 2.0 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 ORY40261.1 - 4e-05 23.2 0.3 0.0015 18.1 0.3 2.3 1 1 0 1 1 1 1 Sulfotransferase domain Sulphotransf PF09037.10 ORY40261.1 - 0.016 14.7 0.1 1.5 8.3 0.0 2.2 2 0 0 2 2 2 0 Stf0 sulphotransferase Sulfotransfer_4 PF17784.1 ORY40261.1 - 0.019 14.8 0.5 0.2 11.5 0.4 2.3 1 1 0 1 1 1 0 Sulfotransferase domain ScsC_N PF18312.1 ORY40261.1 - 0.07 13.0 0.1 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain FYRC PF05965.14 ORY40261.1 - 0.088 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 F/Y rich C-terminus AA_permease_2 PF13520.6 ORY40262.1 - 8e-15 54.6 33.7 1.8e-12 46.9 33.7 2.2 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY40262.1 - 8.8e-14 50.9 33.1 1.6e-08 33.6 16.6 2.1 2 0 0 2 2 2 2 Amino acid permease DUF3093 PF11292.8 ORY40262.1 - 0.04 14.2 5.3 0.59 10.4 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3093) Ctr PF04145.15 ORY40263.1 - 3.7e-20 73.0 0.9 5.3e-20 72.5 0.9 1.2 1 0 0 1 1 1 1 Ctr copper transporter family A_deaminase PF00962.22 ORY40264.1 - 5.6e-22 78.5 0.0 1.2e-21 77.4 0.0 1.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase SH3_9 PF14604.6 ORY40264.1 - 0.057 13.3 0.0 0.55 10.1 0.0 2.4 2 0 0 2 2 2 0 Variant SH3 domain Sel1 PF08238.12 ORY40265.1 - 4.3e-19 68.5 24.0 2.2e-05 24.9 0.2 8.2 8 0 0 8 8 8 5 Sel1 repeat 2OG-FeII_Oxy_3 PF13640.6 ORY40265.1 - 9.2e-08 32.9 0.0 2.3e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DNA_pol_phi PF04931.13 ORY40265.1 - 3.6 5.6 5.7 5.4 5.0 5.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi SUI1 PF01253.22 ORY40266.1 - 8.7e-29 99.9 1.3 1.2e-28 99.4 1.3 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 YfhE PF14152.6 ORY40266.1 - 0.1 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 YfhE-like protein Fe-S_biosyn PF01521.20 ORY40267.1 - 1.1e-17 64.2 0.0 1.3e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis HAUS2 PF15003.6 ORY40270.1 - 0.028 14.2 0.6 0.052 13.3 0.6 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 HWE_HK PF07536.14 ORY40270.1 - 0.044 14.5 0.7 0.23 12.2 0.1 2.1 2 0 0 2 2 2 0 HWE histidine kinase Glyco_hydro_18 PF00704.28 ORY40271.1 - 4.4e-11 43.1 0.3 6.8e-11 42.5 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_26 PF02156.15 ORY40272.1 - 3e-07 30.2 3.5 1.7e-05 24.4 0.0 3.0 3 1 0 3 3 3 2 Glycosyl hydrolase family 26 Nanovirus_C8 PF05629.11 ORY40273.1 - 0.042 14.0 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 Nanovirus component 8 (C8) protein ABM PF03992.16 ORY40278.1 - 0.0017 18.5 0.1 0.0022 18.1 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Oxidored_FMN PF00724.20 ORY40279.1 - 1.4e-80 271.1 0.0 1.7e-80 270.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Meth_synt_1 PF08267.12 ORY40279.1 - 0.0067 16.0 0.0 0.0098 15.4 0.0 1.2 1 0 0 1 1 1 1 Cobalamin-independent synthase, N-terminal domain DUF1629 PF07791.11 ORY40283.1 - 0.1 12.8 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1629) zf-C2H2_jaz PF12171.8 ORY40283.1 - 0.2 12.0 1.1 1.7 9.0 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding OrsD PF12013.8 ORY40283.1 - 0.4 11.1 7.6 0.13 12.7 2.3 2.7 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-H2C2_5 PF13909.6 ORY40283.1 - 7 6.5 16.0 2.8 7.8 3.5 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 ORY40283.1 - 7.5 7.7 10.2 14 6.9 0.2 3.4 2 0 0 2 2 2 0 C2H2-type zinc finger LRR_8 PF13855.6 ORY40335.1 - 0.011 15.5 0.2 0.019 14.7 0.2 1.4 1 0 0 1 1 1 0 Leucine rich repeat RIFIN PF02009.16 ORY40335.1 - 0.012 15.5 1.6 0.014 15.3 1.6 1.2 1 0 0 1 1 1 0 Rifin Sec3_C PF09763.9 ORY40335.1 - 0.96 7.8 8.7 1.1 7.6 8.7 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Menin PF05053.13 ORY40335.1 - 7.6 4.8 10.9 11 4.3 10.9 1.3 1 0 0 1 1 1 0 Menin SOBP PF15279.6 ORY40335.1 - 8.1 7.0 25.0 11 6.5 25.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Utp14 PF04615.13 ORY40335.1 - 8.3 4.8 10.5 9.7 4.6 10.5 1.1 1 0 0 1 1 1 0 Utp14 protein LRR_8 PF13855.6 ORY40336.1 - 3.3e-18 65.2 16.4 6.2e-09 35.5 0.9 4.4 4 0 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 ORY40336.1 - 1.5e-12 47.5 24.6 9e-08 32.3 2.1 5.6 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY40336.1 - 1.4e-06 28.0 13.4 0.18 12.4 0.1 7.0 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 ORY40336.1 - 0.00043 20.1 13.8 0.94 9.7 0.4 6.2 6 0 0 6 6 6 2 Leucine Rich repeat LRR_8 PF13855.6 ORY40338.1 - 4.2e-07 29.6 0.0 7.9e-07 28.7 0.0 1.5 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 ORY40338.1 - 3.9e-05 23.9 0.0 7.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_5 PF13306.6 ORY40338.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.4 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) Mucin PF01456.17 ORY40339.1 - 0.0014 18.6 27.6 0.0031 17.5 27.6 1.6 1 0 0 1 1 1 1 Mucin-like glycoprotein LRR_8 PF13855.6 ORY40339.1 - 0.009 15.8 4.6 9.8 6.0 0.0 4.3 3 1 2 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 ORY40339.1 - 0.016 15.6 10.5 0.022 15.2 0.3 4.4 3 2 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY40339.1 - 0.081 13.0 7.6 18 5.7 0.1 4.7 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 ORY40339.1 - 0.61 10.9 7.7 1e+02 4.1 0.0 5.3 5 1 0 5 5 5 0 Leucine Rich Repeat 6PF2K PF01591.18 ORY40340.1 - 2.7e-64 216.5 0.0 2.3e-35 121.9 0.3 2.4 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 ORY40340.1 - 3.1e-35 121.7 0.0 5.1e-28 98.1 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 ORY40340.1 - 0.028 14.6 0.0 0.31 11.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ribosomal_L7Ae PF01248.26 ORY40340.1 - 0.044 13.5 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Bmp PF02608.14 ORY40342.1 - 7.8e-18 64.5 0.1 9.3e-18 64.2 0.1 1.2 1 1 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like Kelch_4 PF13418.6 ORY40343.1 - 1.8e-22 79.1 9.7 4.8e-07 29.7 0.1 4.2 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.6 ORY40343.1 - 4.6e-18 65.0 9.7 6.6e-05 23.1 0.2 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY40343.1 - 2.1e-17 62.7 7.3 4e-05 23.7 0.3 4.4 4 0 0 4 4 4 4 Kelch motif Kelch_1 PF01344.25 ORY40343.1 - 1.7e-13 49.9 2.0 0.00061 19.3 0.1 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 ORY40343.1 - 2.8e-13 49.5 1.0 0.00017 21.5 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 ORY40343.1 - 1.4e-09 37.5 3.5 0.038 14.0 0.1 4.6 4 1 0 4 4 4 4 Kelch motif 7tm_3 PF00003.22 ORY40344.1 - 3e-32 112.2 25.2 4e-32 111.8 25.2 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF3119 PF11317.8 ORY40344.1 - 1.1 9.6 0.0 1.1 9.6 0.0 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3119) Hydrolase_4 PF12146.8 ORY40345.1 - 2.4e-05 23.7 0.0 3.6e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY40345.1 - 3.2e-05 23.7 0.0 4.6e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY40345.1 - 8.2e-05 23.3 0.2 0.00013 22.6 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 ORY40345.1 - 0.018 15.1 0.2 0.06 13.4 0.1 1.8 1 1 1 2 2 2 0 Thioesterase domain DUF2920 PF11144.8 ORY40345.1 - 0.023 13.9 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Esterase PF00756.20 ORY40345.1 - 0.054 13.1 0.0 0.075 12.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.13 ORY40345.1 - 0.065 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Palm_thioest PF02089.15 ORY40345.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase LIDHydrolase PF10230.9 ORY40345.1 - 0.14 11.7 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase LRR_8 PF13855.6 ORY40346.1 - 6e-12 45.2 5.8 9.1e-07 28.6 1.8 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY40346.1 - 5.9e-11 42.4 8.2 6.7e-05 23.2 1.7 3.7 2 2 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY40346.1 - 4.2e-06 26.6 9.6 0.038 14.5 0.0 4.5 5 0 0 5 5 5 2 Leucine Rich Repeat SSP160 PF06933.11 ORY40346.1 - 1.9e-05 23.1 7.8 1.9e-05 23.1 7.8 2.1 2 0 0 2 2 2 1 Special lobe-specific silk protein SSP160 LRR_6 PF13516.6 ORY40346.1 - 0.0044 17.0 9.4 0.82 9.9 0.1 4.5 4 0 0 4 4 4 1 Leucine Rich repeat MGC-24 PF05283.11 ORY40346.1 - 0.12 12.9 6.4 0.2 12.1 6.4 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mucin PF01456.17 ORY40346.1 - 1.9 8.5 25.1 0.41 10.6 20.2 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein Pil1 PF13805.6 ORY40347.1 - 0.13 11.8 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Eisosome component PIL1 SH3_1 PF00018.28 ORY40348.1 - 6.1e-09 35.4 0.0 9.7e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY40348.1 - 1.2e-08 34.7 0.1 1.8e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY40348.1 - 1.2e-05 24.8 0.0 2.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain CBF PF03914.17 ORY40351.1 - 2.1e-49 167.8 0.0 2.1e-49 167.8 0.0 2.7 2 1 0 2 2 2 1 CBF/Mak21 family RasGAP PF00616.19 ORY40353.1 - 8.6e-08 32.1 0.0 0.00018 21.3 0.0 2.4 2 0 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase RRM_1 PF00076.22 ORY40354.1 - 3.5e-23 81.2 0.0 4.6e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY40354.1 - 0.00027 20.5 0.0 0.00035 20.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 ORY40354.1 - 0.00031 20.7 0.1 0.00047 20.1 0.1 1.3 1 0 0 1 1 1 1 DbpA RNA binding domain RRM_occluded PF16842.5 ORY40354.1 - 0.0027 17.5 0.0 0.0045 16.8 0.0 1.3 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.5 ORY40354.1 - 0.15 12.2 0.0 0.21 11.7 0.0 1.4 1 1 0 1 1 1 0 RNA recognition motif LRR_8 PF13855.6 ORY40355.1 - 1.5e-07 31.1 3.3 2.9e-07 30.1 3.3 1.4 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 ORY40355.1 - 2.8e-07 30.7 12.1 0.00013 22.3 4.1 2.7 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY40355.1 - 0.017 15.6 0.4 1.1 10.1 0.1 2.9 2 0 0 2 2 2 0 Leucine Rich Repeat Acetyltransf_1 PF00583.25 ORY40357.1 - 1.9e-10 41.0 0.0 3.8e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY40357.1 - 7.4e-10 39.1 0.7 1.8e-08 34.7 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY40357.1 - 1.1e-07 31.8 0.6 5e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY40357.1 - 7.6e-06 25.8 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 ORY40357.1 - 0.00042 20.0 0.3 0.0055 16.4 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY40357.1 - 0.0021 18.1 0.0 0.0056 16.8 0.0 1.7 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 ORY40357.1 - 0.0098 16.6 0.2 0.037 14.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY40357.1 - 0.034 14.2 0.2 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain PAZ PF02170.22 ORY40357.1 - 0.071 12.9 6.3 0.15 11.9 6.3 1.5 1 0 0 1 1 1 0 PAZ domain Acetyltransf_4 PF13420.7 ORY40357.1 - 0.13 12.4 0.4 0.27 11.4 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain TFIIA PF03153.13 ORY40357.1 - 3.8 7.4 19.3 5.3 6.9 19.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HTH_48 PF17906.1 ORY40358.1 - 0.28 11.3 0.4 0.28 11.3 0.4 1.5 2 0 0 2 2 2 0 HTH domain in Mos1 transposase Ribosomal_L10 PF00466.20 ORY40359.1 - 0.00019 21.5 0.1 0.00037 20.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_L11_N PF03946.14 ORY40360.1 - 1.6e-20 72.7 0.1 2.3e-20 72.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 ORY40360.1 - 3.7e-17 62.6 0.1 6.8e-17 61.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Chal_sti_synt_C PF02797.15 ORY40360.1 - 0.0051 16.8 0.0 0.0068 16.4 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ATF7IP_BD PF16788.5 ORY40361.1 - 0.44 10.6 12.3 0.59 10.2 12.3 1.1 1 0 0 1 1 1 0 ATF-interacting protein binding domain F-box-like PF12937.7 ORY40363.1 - 2.5e-09 36.9 1.7 5.6e-09 35.8 1.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY40363.1 - 3.2e-07 30.1 0.9 9.3e-07 28.6 0.9 1.8 1 0 0 1 1 1 1 F-box domain ABC_membrane PF00664.23 ORY40364.1 - 1.8e-56 191.8 34.3 1.1e-34 120.4 11.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY40364.1 - 2e-53 180.6 0.2 8e-32 110.6 0.1 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY40364.1 - 6e-09 35.7 4.7 0.045 13.2 0.1 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY40364.1 - 7.5e-08 32.5 0.2 0.013 15.6 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 ORY40364.1 - 1.1e-06 28.7 4.4 0.17 11.7 0.1 4.3 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY40364.1 - 1.6e-06 27.8 0.2 0.057 13.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY40364.1 - 2.2e-06 27.7 0.6 0.019 14.9 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 ORY40364.1 - 4.4e-05 24.1 0.8 0.38 11.2 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ORY40364.1 - 5.8e-05 23.5 0.2 0.055 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 ORY40364.1 - 0.00014 22.1 0.8 0.8 10.0 0.1 3.0 2 1 0 2 2 2 2 AAA domain DUF815 PF05673.13 ORY40364.1 - 0.00034 19.9 0.1 0.077 12.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Dynamin_N PF00350.23 ORY40364.1 - 0.00081 19.5 1.9 0.23 11.5 0.2 2.5 2 0 0 2 2 2 2 Dynamin family AAA_7 PF12775.7 ORY40364.1 - 0.00099 18.7 0.2 0.45 10.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 ORY40364.1 - 0.0012 19.3 0.5 4.1 7.8 0.0 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 ORY40364.1 - 0.0044 16.8 0.0 0.79 9.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 ORY40364.1 - 0.014 15.1 1.5 4.1 7.1 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ORY40364.1 - 0.014 15.9 0.0 9.1 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 ORY40364.1 - 0.019 15.2 0.2 5.8 7.2 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 ORY40364.1 - 0.02 14.2 2.2 2.9 7.1 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 ORY40364.1 - 0.02 15.0 3.4 1.8 8.6 0.3 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 ORY40364.1 - 0.024 14.4 0.3 4.4 7.0 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MeaB PF03308.16 ORY40364.1 - 0.026 13.5 0.6 1.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_PrkA PF08298.11 ORY40364.1 - 0.029 13.3 0.4 0.44 9.4 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain AAA_25 PF13481.6 ORY40364.1 - 0.036 13.6 0.4 0.88 9.1 0.1 2.6 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 ORY40364.1 - 0.11 12.0 0.9 1.5 8.4 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 ORY40364.1 - 0.15 11.8 0.7 15 5.3 0.1 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_24 PF13479.6 ORY40364.1 - 0.17 11.6 0.1 7.7 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 ORY40364.1 - 0.2 11.2 0.1 7.5 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 ORY40364.1 - 0.27 11.2 3.1 1.3 9.1 0.2 2.7 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP-synt_ab PF00006.25 ORY40364.1 - 0.31 10.7 0.9 7.8 6.1 0.0 2.7 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SNF2_N PF00176.23 ORY40365.1 - 9.4e-65 218.6 1.8 1.5e-64 217.9 1.8 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY40365.1 - 2.2e-17 63.4 0.0 6.9e-17 61.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 ORY40365.1 - 4.5e-13 48.9 0.5 1.9e-07 30.9 0.1 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.29 ORY40365.1 - 0.00016 21.5 0.0 0.00043 20.1 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 ORY40365.1 - 0.00029 20.1 3.6 0.00044 19.5 0.0 2.8 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 CHDCT2 PF08074.11 ORY40365.1 - 0.053 13.7 2.6 0.58 10.3 0.0 3.5 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain RNA_pol_Rpc34 PF05158.12 ORY40367.1 - 1.4e-80 271.3 0.0 1.6e-80 271.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.11 ORY40367.1 - 1e-05 26.1 0.0 0.032 14.9 0.0 2.5 1 1 1 2 2 2 2 Replication protein A C terminal B-block_TFIIIC PF04182.12 ORY40367.1 - 3e-05 24.1 0.2 0.046 13.9 0.2 2.4 2 0 0 2 2 2 2 B-block binding subunit of TFIIIC MarR_2 PF12802.7 ORY40367.1 - 6.1e-05 22.8 0.0 0.0019 18.1 0.0 2.3 2 0 0 2 2 2 1 MarR family MarR PF01047.22 ORY40367.1 - 0.00024 21.0 0.0 0.17 11.8 0.0 2.4 2 0 0 2 2 2 2 MarR family TrmB PF01978.19 ORY40367.1 - 0.0031 17.4 0.0 0.39 10.6 0.0 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB TFIIE_alpha PF02002.17 ORY40367.1 - 0.008 16.0 0.3 1.2 9.0 0.0 2.4 1 1 1 2 2 2 1 TFIIE alpha subunit HTH_27 PF13463.6 ORY40367.1 - 0.024 15.1 0.0 3 8.4 0.0 2.3 2 0 0 2 2 2 0 Winged helix DNA-binding domain CSD PF00313.22 ORY40367.1 - 0.083 12.8 0.5 0.15 11.9 0.5 1.4 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain HTH_6 PF01418.17 ORY40367.1 - 0.13 12.3 0.1 5.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family DUF2250 PF10007.9 ORY40367.1 - 0.13 12.4 0.4 11 6.3 0.1 2.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2250) Rrf2 PF02082.20 ORY40367.1 - 0.2 12.0 0.7 7.3 7.0 0.1 2.8 3 0 0 3 3 3 0 Transcriptional regulator RRM_1 PF00076.22 ORY40368.1 - 8.5e-14 51.1 0.0 2e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3439 PF11921.8 ORY40369.1 - 0.00053 19.9 28.1 0.039 13.9 14.8 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3439) Mucin PF01456.17 ORY40369.1 - 0.0021 18.0 49.1 0.078 13.0 28.2 2.4 2 0 0 2 2 2 2 Mucin-like glycoprotein Dicty_REP PF05086.12 ORY40369.1 - 5.2 4.9 5.9 7.8 4.3 5.9 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glyco_hydro_18 PF00704.28 ORY40370.1 - 7.4e-10 39.0 9.9 1.2e-09 38.3 9.8 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Mucin PF01456.17 ORY40370.1 - 0.00097 19.1 36.4 0.0021 18.1 36.4 1.6 1 0 0 1 1 1 1 Mucin-like glycoprotein Acetyltransf_1 PF00583.25 ORY40371.1 - 1.3e-08 35.1 0.0 1.8e-08 34.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY40371.1 - 2.5e-08 33.9 0.0 4.9e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY40371.1 - 7.2e-08 32.7 0.0 1.6e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY40371.1 - 2.1e-05 24.4 0.1 3.8e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 ORY40371.1 - 0.0043 17.1 0.0 0.038 14.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 ORY40371.1 - 0.08 12.7 1.1 0.35 10.6 0.2 2.3 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain, PanZ COX15-CtaA PF02628.15 ORY40372.1 - 5.6e-103 344.4 10.0 7e-103 344.1 10.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein YobH PF13996.6 ORY40372.1 - 0.077 13.1 0.1 0.26 11.4 0.1 1.9 1 0 0 1 1 1 0 YobH-like protein DUF2627 PF11118.8 ORY40372.1 - 7.6 7.2 7.9 0.58 10.8 0.1 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2627) Gti1_Pac2 PF09729.9 ORY40374.1 - 6e-28 98.2 5.9 1.7e-21 77.1 0.0 3.2 2 1 1 3 3 3 2 Gti1/Pac2 family Elongin_A PF06881.11 ORY40374.1 - 0.034 14.7 0.8 0.07 13.7 0.8 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Gti1_Pac2 PF09729.9 ORY40375.1 - 2.9e-21 76.4 0.0 6.6e-21 75.2 0.0 1.6 2 0 0 2 2 2 1 Gti1/Pac2 family Rad9 PF04139.13 ORY40375.1 - 0.027 14.0 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Rad9 Gti1_Pac2 PF09729.9 ORY40376.1 - 1.1e-25 90.7 0.9 4.5e-20 72.5 0.0 2.5 2 1 1 3 3 3 2 Gti1/Pac2 family Gti1_Pac2 PF09729.9 ORY40378.1 - 2.3e-25 89.7 0.8 7.4e-20 71.8 0.0 2.9 2 1 1 3 3 3 2 Gti1/Pac2 family Dynamin_M PF01031.20 ORY40379.1 - 1.9e-98 329.2 0.0 3.6e-98 328.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 ORY40379.1 - 7.2e-56 188.8 0.0 1.3e-55 188.0 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 ORY40379.1 - 2.8e-27 94.7 3.4 2.8e-27 94.7 3.4 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 ORY40379.1 - 9e-05 22.5 0.4 0.0029 17.7 0.4 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY40379.1 - 0.066 13.6 0.0 0.23 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain Thioredoxin_14 PF18402.1 ORY40379.1 - 0.11 12.5 0.5 1.8 8.5 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin-like domain SGTA_dimer PF16546.5 ORY40380.1 - 8.9e-23 79.8 0.3 2e-22 78.8 0.3 1.6 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 ORY40380.1 - 7.4e-20 69.9 10.8 3.3e-10 39.3 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORY40380.1 - 1e-17 63.5 12.8 4.7e-07 29.4 0.1 3.3 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.17 ORY40380.1 - 2.8e-17 61.4 9.6 6.2e-08 32.2 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY40380.1 - 5.6e-13 48.0 6.9 2.6e-06 27.2 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY40380.1 - 1.8e-10 40.1 2.9 1.1e-05 25.1 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY40380.1 - 4.6e-10 39.2 6.3 0.00062 20.0 1.6 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat STI1 PF17830.1 ORY40380.1 - 3.1e-09 36.6 20.8 2.9e-08 33.5 15.1 3.6 3 1 1 4 4 3 1 STI1 domain TPR_19 PF14559.6 ORY40380.1 - 4.3e-09 36.7 10.9 6.3e-08 33.0 0.3 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY40380.1 - 5.8e-08 32.9 5.3 0.00019 21.9 0.0 3.9 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY40380.1 - 1.9e-07 31.3 6.4 1.4e-05 25.3 2.7 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY40380.1 - 2.5e-06 27.2 3.7 0.057 13.3 0.3 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_15 PF13429.6 ORY40380.1 - 5.4e-05 22.6 1.5 5.4e-05 22.6 1.5 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY40380.1 - 0.00016 22.3 11.7 0.0035 18.0 0.9 3.0 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY40380.1 - 0.00031 20.8 1.2 0.0057 16.8 0.2 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.17 ORY40380.1 - 0.0059 17.1 1.3 0.037 14.5 0.2 2.1 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_6 PF13174.6 ORY40380.1 - 0.0078 16.8 7.1 0.063 13.9 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY40380.1 - 0.017 15.3 2.8 0.044 14.0 2.7 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 ORY40380.1 - 0.019 15.0 5.3 0.19 11.8 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY40380.1 - 0.042 13.9 0.6 0.33 11.0 0.0 2.4 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_4 PF07721.14 ORY40380.1 - 0.12 13.1 6.4 16 6.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat XPC-binding PF09280.11 ORY40380.1 - 0.13 12.0 3.9 3.4 7.5 0.8 2.4 1 1 1 2 2 2 0 XPC-binding domain GerD PF17898.1 ORY40380.1 - 0.44 10.5 15.1 15 5.6 10.6 3.3 2 1 0 2 2 2 0 Spore germination GerD central core domain MIT PF04212.18 ORY40380.1 - 0.47 10.6 12.8 0.74 9.9 1.5 3.3 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain CN_hydrolase PF00795.22 ORY40382.1 - 9.5e-12 44.8 0.0 3.4e-09 36.4 0.0 2.1 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase TPR_1 PF00515.28 ORY40383.1 - 9.9e-42 139.1 23.1 4.4e-08 32.6 2.5 12.2 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_2 PF07719.17 ORY40383.1 - 1.2e-41 137.4 12.0 5.1e-06 26.2 1.4 12.2 13 0 0 13 13 12 8 Tetratricopeptide repeat TPR_12 PF13424.6 ORY40383.1 - 1.7e-33 114.7 6.3 4.2e-09 36.6 0.0 8.2 6 1 3 9 9 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 ORY40383.1 - 9.6e-28 94.1 30.1 0.00017 21.6 0.3 12.0 13 0 0 13 13 11 7 Tetratricopeptide repeat TPR_7 PF13176.6 ORY40383.1 - 8.6e-27 91.2 10.6 0.00078 19.3 0.0 10.5 12 0 0 12 12 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 ORY40383.1 - 9.7e-27 93.3 0.1 0.016 15.7 1.8 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_6 PF13174.6 ORY40383.1 - 6.1e-26 89.3 6.0 0.0088 16.6 0.1 10.3 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.6 ORY40383.1 - 1.5e-21 75.2 0.0 0.0077 17.0 0.0 9.9 2 2 8 10 10 10 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORY40383.1 - 1.2e-20 72.9 2.5 3.6e-06 26.6 0.8 7.2 5 2 3 8 8 8 3 TPR repeat TPR_16 PF13432.6 ORY40383.1 - 8.3e-18 64.8 0.0 5.8e-05 23.7 0.0 7.5 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY40383.1 - 7.1e-15 54.3 10.6 0.0032 17.3 0.3 7.9 8 0 0 8 8 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY40383.1 - 2.7e-14 53.1 13.1 0.001 19.2 0.1 6.1 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 ORY40383.1 - 3.1e-11 43.3 0.0 0.14 12.3 0.0 5.3 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY40383.1 - 4.6e-09 36.1 2.4 0.0064 15.9 0.0 4.9 3 1 1 5 5 5 2 MalT-like TPR region TPR_21 PF09976.9 ORY40383.1 - 4.8e-08 32.9 11.2 0.00019 21.2 1.6 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat-like domain TPR_17 PF13431.6 ORY40383.1 - 6.9e-08 32.3 16.2 0.014 15.7 0.2 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat RPN7 PF10602.9 ORY40383.1 - 8.8e-07 28.8 11.1 2.7 7.7 0.0 6.9 3 3 1 5 5 5 2 26S proteasome subunit RPN7 TPR_15 PF13429.6 ORY40383.1 - 2e-05 23.9 0.2 0.024 13.8 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat Wzy_C_2 PF11846.8 ORY40383.1 - 0.00017 21.6 0.0 0.4 10.6 0.0 4.2 3 1 1 4 4 4 1 Virulence factor membrane-bound polymerase, C-terminal NARP1 PF12569.8 ORY40383.1 - 0.00023 20.2 6.2 1.2 7.9 0.0 4.4 3 1 0 4 4 4 2 NMDA receptor-regulated protein 1 DUF3808 PF10300.9 ORY40383.1 - 0.00039 19.3 0.9 0.0015 17.4 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_20 PF14561.6 ORY40383.1 - 0.0014 18.9 5.8 0.22 11.9 0.0 5.4 6 1 1 7 7 5 1 Tetratricopeptide repeat DUF4810 PF16068.5 ORY40383.1 - 0.0023 18.4 5.4 1.7 9.2 0.0 5.7 6 0 0 6 6 5 1 Domain of unknown function (DUF4810) PPR PF01535.20 ORY40383.1 - 0.0067 16.6 5.1 32 5.1 0.0 6.3 7 0 0 7 7 6 0 PPR repeat Foie-gras_1 PF11817.8 ORY40383.1 - 0.016 14.8 12.6 5.6 6.5 0.3 5.6 3 2 2 6 6 6 0 Foie gras liver health family 1 MA3 PF02847.17 ORY40383.1 - 0.024 14.6 0.3 3.7 7.6 0.0 3.1 2 0 0 2 2 2 0 MA3 domain BTAD PF03704.17 ORY40383.1 - 0.028 14.9 0.4 10 6.6 0.0 3.7 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Rapsyn_N PF10579.9 ORY40383.1 - 0.047 13.8 1.1 0.72 10.0 0.1 3.1 3 1 1 4 4 3 0 Rapsyn N-terminal myristoylation and linker region DUF627 PF04781.12 ORY40383.1 - 0.054 13.5 2.2 1 9.4 0.5 3.6 3 2 0 3 3 2 0 Protein of unknown function (DUF627) Snf7 PF03357.21 ORY40383.1 - 0.13 11.8 1.9 0.36 10.4 1.9 1.7 1 0 0 1 1 1 0 Snf7 SHNi-TPR PF10516.9 ORY40383.1 - 0.14 11.6 0.1 2.9 7.4 0.0 3.1 4 0 0 4 4 3 0 SHNi-TPR DUF4919 PF16266.5 ORY40383.1 - 0.54 10.2 4.4 3.4 7.6 1.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4919) MIT PF04212.18 ORY40383.1 - 0.9 9.7 21.2 33 4.6 0.0 8.6 10 0 0 10 10 9 0 MIT (microtubule interacting and transport) domain Vps54 PF07928.12 ORY40384.1 - 7e-41 139.8 0.2 2.7e-40 137.9 0.2 2.1 1 0 0 1 1 1 1 Vps54-like protein UvrA_inter PF17760.1 ORY40384.1 - 0.0069 16.4 0.0 1.1 9.3 0.0 2.8 2 0 0 2 2 2 2 UvrA interaction domain Glyco_hydro_19 PF00182.19 ORY40385.1 - 9.3e-23 81.3 1.9 9.3e-23 81.3 1.9 2.8 2 1 0 2 2 2 1 Chitinase class I CBM_5_12 PF02839.14 ORY40385.1 - 1.7 9.3 9.8 0.63 10.7 5.3 2.7 1 1 0 1 1 1 0 Carbohydrate binding domain Baculo_p74 PF04583.12 ORY40385.1 - 5.9 6.3 5.6 8.5 5.8 4.9 1.6 2 0 0 2 2 2 0 Baculoviridae p74 conserved region Glyco_hydro_19 PF00182.19 ORY40386.1 - 1.5e-20 74.1 0.4 3.2e-20 73.0 0.4 1.5 1 0 0 1 1 1 1 Chitinase class I Mucin PF01456.17 ORY40386.1 - 0.005 16.8 33.0 0.005 16.8 33.0 2.3 2 0 0 2 2 2 1 Mucin-like glycoprotein Chorismate_bind PF00425.18 ORY40387.1 - 1.1e-93 313.6 0.0 9e-92 307.3 0.0 2.1 2 0 0 2 2 2 2 chorismate binding enzyme Anth_synt_I_N PF04715.13 ORY40387.1 - 2.2e-27 96.0 0.0 2.7e-25 89.3 0.0 2.9 3 1 0 3 3 3 2 Anthranilate synthase component I, N terminal region Phage_Treg PF04761.12 ORY40388.1 - 0.07 13.2 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator STE3 PF02076.15 ORY40389.1 - 0.056 12.6 2.7 0.06 12.5 2.7 1.2 1 0 0 1 1 1 0 Pheromone A receptor 7tm_1 PF00001.21 ORY40389.1 - 0.062 12.6 3.0 0.075 12.3 3.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF92 PF01940.16 ORY40389.1 - 0.08 12.4 0.1 0.097 12.1 0.1 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF92 Sprouty PF05210.13 ORY40389.1 - 0.12 12.8 0.3 6.5 7.2 0.1 2.2 2 0 0 2 2 2 0 Sprouty protein (Spry) Ytca PF17090.5 ORY40390.1 - 0.044 14.3 2.2 0.044 14.3 2.2 3.0 3 0 0 3 3 3 0 Uncharacterised protein family 7tm_1 PF00001.21 ORY40390.1 - 2 7.6 13.8 3.2 7.0 13.0 1.8 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) SfLAP PF11139.8 ORY40391.1 - 0.00044 19.8 7.0 0.00052 19.5 7.0 1.1 1 0 0 1 1 1 1 Sap, sulfolipid-1-addressing protein 7tm_1 PF00001.21 ORY40391.1 - 0.0019 17.5 11.2 0.0024 17.3 11.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ATP-synt_8 PF00895.20 ORY40391.1 - 0.073 13.5 1.9 5.4 7.5 0.0 2.6 3 0 0 3 3 3 0 ATP synthase protein 8 Rubella_E1 PF05748.11 ORY40391.1 - 0.12 11.3 0.8 0.17 10.8 0.8 1.1 1 0 0 1 1 1 0 Rubella membrane glycoprotein E1 TatC PF00902.18 ORY40391.1 - 0.12 12.2 10.7 0.23 11.3 10.7 1.5 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) Holin_2-3 PF13272.6 ORY40391.1 - 0.14 12.5 6.4 0.17 12.2 1.0 2.4 1 1 1 2 2 2 0 Putative 2/3 transmembrane domain holin 4HBT_2 PF13279.6 ORY40392.1 - 0.01 16.3 0.0 0.02 15.3 0.0 1.4 1 1 0 1 1 1 0 Thioesterase-like superfamily Phe_hydrox_dim PF07976.12 ORY40395.1 - 0.16 12.0 0.0 0.19 11.8 0.0 1.1 1 0 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain ABC_membrane PF00664.23 ORY40399.1 - 2.4e-67 227.5 33.7 1.3e-42 146.4 11.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY40399.1 - 5.9e-55 185.5 0.2 8.8e-30 104.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY40399.1 - 2.1e-11 43.7 6.3 0.00062 19.3 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY40399.1 - 1.5e-09 37.9 1.1 0.0011 19.1 0.2 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY40399.1 - 1.7e-07 30.8 1.7 0.0095 15.7 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 ORY40399.1 - 5.2e-07 29.8 2.4 0.029 14.2 0.0 3.3 2 2 2 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORY40399.1 - 1.3e-06 29.0 0.0 0.049 14.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORY40399.1 - 1.7e-06 28.1 3.0 0.0011 18.9 1.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 ORY40399.1 - 3.3e-06 27.7 3.9 0.038 14.5 0.2 3.2 2 1 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 ORY40399.1 - 2.4e-05 24.5 5.5 0.0017 18.4 1.6 3.0 2 0 0 2 2 2 1 Dynamin family FtsK_SpoIIIE PF01580.18 ORY40399.1 - 4e-05 23.1 1.0 0.26 10.6 0.2 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_22 PF13401.6 ORY40399.1 - 9e-05 22.8 1.7 0.23 11.7 0.1 3.4 2 2 1 3 3 3 2 AAA domain MeaB PF03308.16 ORY40399.1 - 0.00014 20.9 1.1 0.011 14.8 0.1 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 ORY40399.1 - 0.00042 20.5 3.8 0.015 15.4 0.1 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain NB-ARC PF00931.22 ORY40399.1 - 0.00083 18.6 0.5 0.26 10.4 0.2 2.4 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 ORY40399.1 - 0.0015 18.5 2.2 1.8 8.5 0.0 3.1 4 0 0 4 4 2 2 NACHT domain AAA_7 PF12775.7 ORY40399.1 - 0.0017 17.9 0.6 0.85 9.1 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_15 PF13175.6 ORY40399.1 - 0.0019 18.0 0.7 1.6 8.4 0.3 2.3 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 ORY40399.1 - 0.002 17.4 0.3 0.24 10.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin cobW PF02492.19 ORY40399.1 - 0.002 17.7 1.4 0.94 9.0 0.2 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 ORY40399.1 - 0.002 17.2 0.2 1.5 7.8 0.2 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein ATP-synt_ab PF00006.25 ORY40399.1 - 0.0023 17.6 0.0 0.059 13.0 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 ORY40399.1 - 0.0024 17.6 1.2 0.82 9.4 0.3 2.8 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY40399.1 - 0.0025 18.4 0.2 2.3 8.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 ORY40399.1 - 0.0043 17.3 0.2 1.2 9.4 0.0 2.7 3 0 0 3 3 2 1 AAA domain DUF815 PF05673.13 ORY40399.1 - 0.0062 15.7 0.5 2.7 7.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Roc PF08477.13 ORY40399.1 - 0.0069 16.6 0.3 4.5 7.5 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 ORY40399.1 - 0.013 15.0 0.0 6 6.4 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Ploopntkinase3 PF18751.1 ORY40399.1 - 0.015 15.2 0.4 5.1 7.0 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 TrwB_AAD_bind PF10412.9 ORY40399.1 - 0.017 14.1 1.7 2.7 6.8 0.2 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 ORY40399.1 - 0.018 15.4 0.2 3.2 8.2 0.1 2.8 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 ORY40399.1 - 0.018 14.6 0.1 0.95 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ORY40399.1 - 0.02 15.0 0.0 8.8 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 ORY40399.1 - 0.027 14.3 1.4 1.6 8.5 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 ORY40399.1 - 0.027 14.5 1.5 13 5.8 0.1 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.9 ORY40399.1 - 0.039 12.8 2.6 0.35 9.6 0.3 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class MobB PF03205.14 ORY40399.1 - 0.039 13.8 0.5 11 6.0 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.18 ORY40399.1 - 0.042 13.4 0.1 1.7 8.2 0.1 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.9 ORY40399.1 - 0.048 13.4 0.3 4.4 7.0 0.2 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.14 ORY40399.1 - 0.053 12.8 0.0 0.61 9.3 0.0 2.1 2 0 0 2 2 2 0 KAP family P-loop domain Septin PF00735.18 ORY40399.1 - 0.057 12.7 0.2 4 6.6 0.0 2.3 2 0 0 2 2 2 0 Septin TsaE PF02367.17 ORY40399.1 - 0.11 12.5 0.1 28 4.7 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GBP PF02263.19 ORY40399.1 - 0.11 11.7 0.1 2.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain Regnase_1_C PF18561.1 ORY40399.1 - 0.17 11.6 0.2 0.52 10.1 0.2 1.8 1 0 0 1 1 1 0 Endoribonuclease Regnase 1/ ZC3H12 C-terminal domain AAA PF00004.29 ORY40399.1 - 0.28 11.6 1.0 33 4.9 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Lipoxygenase PF00305.19 ORY40400.1 - 6e-72 243.1 0.1 6.4e-70 236.4 0.0 2.2 1 1 1 2 2 2 2 Lipoxygenase PLAT PF01477.23 ORY40400.1 - 0.00023 21.7 0.3 0.0011 19.5 0.3 2.2 1 1 0 1 1 1 1 PLAT/LH2 domain Lipase_GDSL_3 PF14606.6 ORY40400.1 - 0.078 13.1 0.3 0.54 10.4 0.3 2.1 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family SET PF00856.28 ORY40401.1 - 8e-14 52.4 0.0 2.9e-13 50.6 0.0 1.9 1 1 0 1 1 1 1 SET domain Acyltransferase PF01553.21 ORY40402.1 - 1.8e-13 50.3 0.0 3.1e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 ORY40402.1 - 1.8e-07 31.1 0.0 3.7e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Pkinase PF00069.25 ORY40403.1 - 4.4e-45 154.1 0.0 5.8e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY40403.1 - 9e-17 61.2 0.0 1.3e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY40403.1 - 6.5e-05 22.4 0.0 0.00015 21.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like WW PF00397.26 ORY40403.1 - 0.00022 21.2 2.8 0.00022 21.2 2.8 2.5 3 0 0 3 3 3 1 WW domain Kdo PF06293.14 ORY40403.1 - 0.0052 16.1 0.0 0.0085 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5388 PF17363.2 ORY40403.1 - 0.04 14.1 0.0 0.091 13.0 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5388) Pkinase PF00069.25 ORY40404.1 - 9.4e-49 166.1 0.0 1.2e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY40404.1 - 2.1e-17 63.3 0.0 3.1e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase WW PF00397.26 ORY40404.1 - 0.0017 18.4 0.5 0.0051 16.9 0.5 1.8 1 0 0 1 1 1 1 WW domain MecA PF05389.12 ORY40404.1 - 0.19 11.4 0.1 0.32 10.6 0.1 1.3 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) Kdo PF06293.14 ORY40404.1 - 0.2 11.0 0.0 0.32 10.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PBP1_TM PF14812.6 ORY40404.1 - 0.31 11.5 2.4 0.73 10.2 2.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF647 PF04884.14 ORY40405.1 - 7e-82 274.7 0.5 9.8e-82 274.2 0.5 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis TNT PF14021.6 ORY40405.1 - 0.014 15.9 0.0 0.034 14.7 0.0 1.6 1 0 0 1 1 1 0 Tuberculosis necrotizing toxin Med6 PF04934.14 ORY40406.1 - 4.7e-34 117.1 2.6 6.4e-34 116.6 2.6 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component LSM14 PF12701.7 ORY40407.1 - 2.2e-28 98.1 0.1 3.8e-28 97.4 0.1 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 ORY40407.1 - 7.9e-16 58.8 2.0 7.9e-16 58.8 2.0 2.4 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.6 ORY40407.1 - 4.7e-07 29.9 0.1 1.2e-06 28.6 0.1 1.7 1 0 0 1 1 1 1 Ataxin 2 SM domain Peptidase_S39 PF02122.15 ORY40407.1 - 0.024 14.2 0.3 0.046 13.3 0.3 1.4 1 0 0 1 1 1 0 Peptidase S39 WD-3 PF09765.9 ORY40408.1 - 2.5e-17 63.1 0.0 2.9e-17 62.9 0.0 1.1 1 0 0 1 1 1 1 WD-repeat region DUF3073 PF11273.8 ORY40408.1 - 0.11 13.3 0.0 0.16 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3073) DUF2408 PF10303.9 ORY40409.1 - 5.4e-11 43.2 0.0 6.9e-08 33.1 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2408) HOASN PF14515.6 ORY40410.1 - 0.077 13.4 0.3 0.1 13.0 0.3 1.2 1 0 0 1 1 1 0 Haem-oxygenase-associated N-terminal helices DDE_Tnp_4 PF13359.6 ORY40411.1 - 5.2e-09 36.0 0.0 6e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Glyco_hydro_16 PF00722.21 ORY40413.1 - 1.7e-28 99.3 1.2 2.7e-28 98.6 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 RNA_pol_Rpc34 PF05158.12 ORY40414.1 - 1.2e-09 38.1 0.0 1.5e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit Cyclin_N PF00134.23 ORY40415.1 - 1.1e-06 28.4 0.3 3.7e-06 26.7 0.2 1.8 1 1 1 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORY40415.1 - 0.0022 18.1 0.2 0.0022 18.1 0.2 2.7 2 1 1 3 3 3 1 Cyclin, C-terminal domain DNA_pol_E_B PF04042.16 ORY40416.1 - 8.6e-38 129.8 0.1 1.2e-37 129.4 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 ORY40416.1 - 4.7e-36 123.8 0.0 7.1e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Rieske PF00355.26 ORY40417.1 - 4.6e-12 45.7 0.1 1.1e-11 44.5 0.1 1.6 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 ORY40417.1 - 0.00026 21.4 1.2 0.00026 21.4 1.2 1.9 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region SUKH-4 PF14435.6 ORY40417.1 - 0.016 15.3 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 SUKH-4 immunity protein Pkinase PF00069.25 ORY40418.1 - 4.5e-60 203.2 0.0 6.1e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY40418.1 - 2.2e-29 102.5 0.0 3.4e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY40418.1 - 0.00089 18.6 0.1 0.002 17.5 0.1 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY40418.1 - 0.0011 18.0 0.1 0.0018 17.3 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY40418.1 - 0.041 13.8 0.3 0.11 12.4 0.3 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Activator_LAG-3 PF11498.8 ORY40418.1 - 4.6 6.1 13.8 7.4 5.4 13.8 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Glyco_hydro_18 PF00704.28 ORY40419.1 - 1.8e-06 27.9 0.2 2.5e-06 27.4 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase PF00069.25 ORY40420.1 - 8.3e-71 238.4 0.0 1e-70 238.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY40420.1 - 1.8e-50 171.7 0.0 2.3e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY40420.1 - 0.00032 19.8 0.1 0.012 14.5 0.1 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 ORY40420.1 - 0.0047 15.7 0.0 0.0067 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY40420.1 - 0.028 13.7 0.1 0.072 12.4 0.0 1.7 2 1 0 2 2 2 0 Kinase-like MORN PF02493.20 ORY40421.1 - 5.1e-11 41.8 10.1 6.4e-05 22.6 2.2 4.1 4 0 0 4 4 4 3 MORN repeat DUF1107 PF06526.12 ORY40421.1 - 0.18 11.7 1.5 8.1 6.4 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1107) Bromodomain PF00439.25 ORY40422.1 - 4.4e-16 58.7 0.0 7.2e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Bromodomain Ndc1_Nup PF09531.10 ORY40422.1 - 0.0064 15.2 5.3 0.0072 15.1 5.3 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Clat_adaptor_s PF01217.20 ORY40423.1 - 7.2e-46 155.7 0.1 8.3e-46 155.4 0.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1646 PF07854.12 ORY40423.1 - 0.019 14.3 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1646) PIH1 PF08190.12 ORY40423.1 - 0.15 11.5 0.1 0.31 10.5 0.0 1.5 2 0 0 2 2 2 0 PIH1 N-terminal domain Rootletin PF15035.6 ORY40424.1 - 0.39 10.7 33.5 0.59 10.1 21.0 2.8 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion GRDB PF07355.12 ORY40424.1 - 0.46 9.7 4.8 0.75 9.0 4.8 1.3 1 0 0 1 1 1 0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) Atg8 PF02991.16 ORY40425.1 - 5.5e-50 167.9 0.1 6.3e-50 167.7 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 ORY40425.1 - 3.4e-07 30.6 0.1 4.3e-07 30.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 APG5 PF04106.12 ORY40425.1 - 0.11 12.1 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg5 Ribosomal_L29 PF00831.23 ORY40426.1 - 0.0022 17.9 1.9 0.0087 16.0 0.7 2.3 2 0 0 2 2 2 1 Ribosomal L29 protein HOOK PF05622.12 ORY40426.1 - 0.0054 14.9 4.9 0.006 14.8 4.9 1.0 1 0 0 1 1 1 1 HOOK protein DUF1192 PF06698.11 ORY40426.1 - 0.052 13.6 1.6 0.12 12.5 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Peptidase_C98 PF15499.6 ORY40426.1 - 0.076 12.5 0.6 0.083 12.4 0.6 1.2 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase RhoGAP PF00620.27 ORY40427.1 - 5.4e-35 120.5 0.0 9.3e-35 119.7 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Galactosyl_T PF01762.21 ORY40428.1 - 7.9e-07 29.1 0.0 0.0015 18.4 0.0 2.2 1 1 1 2 2 2 2 Galactosyltransferase HOOK PF05622.12 ORY40429.1 - 1.5e-77 261.4 63.8 6.9e-68 229.4 30.5 2.3 2 0 0 2 2 2 2 HOOK protein Filament PF00038.21 ORY40429.1 - 0.00022 20.9 41.4 0.00022 20.9 41.4 4.2 1 1 2 3 3 3 2 Intermediate filament protein CALCOCO1 PF07888.11 ORY40429.1 - 0.0031 16.4 20.2 0.0031 16.4 20.2 3.8 2 1 1 3 3 3 1 Calcium binding and coiled-coil domain (CALCOCO1) like bZIP_1 PF00170.21 ORY40429.1 - 0.019 15.0 6.8 0.019 15.0 6.8 9.0 9 1 1 10 10 10 0 bZIP transcription factor TSC22 PF01166.18 ORY40429.1 - 0.071 13.4 0.6 0.071 13.4 0.6 8.4 7 2 4 11 11 11 0 TSC-22/dip/bun family WD40_alt PF14077.6 ORY40429.1 - 0.19 11.6 4.1 5 7.1 0.0 4.3 4 0 0 4 4 4 0 Alternative WD40 repeat motif DUF3800 PF12686.7 ORY40429.1 - 0.41 11.3 6.1 67 4.1 6.1 3.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) bZIP_1 PF00170.21 ORY40430.1 - 0.0084 16.2 3.5 0.15 12.2 1.0 2.3 2 0 0 2 2 2 1 bZIP transcription factor DivIC PF04977.15 ORY40430.1 - 0.012 15.3 1.3 1.3 8.8 0.3 2.1 2 0 0 2 2 2 0 Septum formation initiator Nnf1 PF03980.14 ORY40430.1 - 0.029 14.8 2.0 1.4 9.3 0.4 2.3 2 0 0 2 2 2 0 Nnf1 zf-GRF PF06839.12 ORY40430.1 - 0.029 14.5 0.2 0.056 13.5 0.2 1.4 1 0 0 1 1 1 0 GRF zinc finger JAKMIP_CC3 PF16034.5 ORY40430.1 - 0.038 13.9 0.5 0.038 13.9 0.5 2.0 1 1 1 2 2 2 0 JAKMIP CC3 domain WD40_alt PF14077.6 ORY40430.1 - 0.064 13.1 1.4 0.072 13.0 0.1 1.7 2 0 0 2 2 2 0 Alternative WD40 repeat motif CENP-H PF05837.12 ORY40430.1 - 0.069 13.6 0.2 0.1 13.0 0.2 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Mto2_bdg PF12808.7 ORY40430.1 - 0.084 13.2 3.4 0.35 11.2 0.1 2.4 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region TolA_bind_tri PF16331.5 ORY40430.1 - 0.13 12.3 2.3 6.6 6.9 0.3 2.3 2 0 0 2 2 2 0 TolA binding protein trimerisation HALZ PF02183.18 ORY40430.1 - 0.17 12.1 4.8 0.72 10.1 0.3 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper Cep57_CLD_2 PF14197.6 ORY40430.1 - 0.17 12.0 5.4 2.1 8.5 0.3 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DASH_Duo1 PF08651.10 ORY40430.1 - 0.22 11.3 0.1 0.22 11.3 0.1 1.7 2 0 0 2 2 2 0 DASH complex subunit Duo1 bZIP_2 PF07716.15 ORY40430.1 - 0.47 10.6 6.5 6.1 7.0 0.4 2.4 2 0 0 2 2 2 0 Basic region leucine zipper JIP_LZII PF16471.5 ORY40430.1 - 3.5 7.9 6.6 9 6.5 1.3 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II PLDc_2 PF13091.6 ORY40431.1 - 6.9e-05 22.8 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 PLD-like domain PLDc PF00614.22 ORY40431.1 - 0.0034 17.5 0.2 0.0061 16.7 0.2 1.5 1 0 0 1 1 1 1 Phospholipase D Active site motif Ribonucleas_3_3 PF14622.6 ORY40432.1 - 1.6e-10 41.2 0.0 0.0003 21.0 0.0 2.2 1 1 1 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 ORY40432.1 - 0.0035 17.9 0.0 1.8 9.2 0.0 2.6 1 1 1 2 2 2 2 Ribonuclease III domain DUF3924 PF13062.6 ORY40432.1 - 0.32 11.0 1.5 1.2 9.2 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) B56 PF01603.20 ORY40433.1 - 4.2e-197 655.1 4.8 5.1e-197 654.9 4.8 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) NAD1 PF18778.1 ORY40433.1 - 0.028 14.5 0.3 0.23 11.5 0.3 2.1 1 1 0 1 1 1 0 Novel AID APOBEC clade 1 Sec7_N PF12783.7 ORY40433.1 - 0.12 12.2 1.7 1.6 8.6 0.3 2.5 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Complex1_LYR PF05347.15 ORY40434.1 - 1.3e-11 44.3 1.5 1.7e-11 43.9 1.5 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF5521 PF17659.1 ORY40434.1 - 0.067 11.0 1.0 0.077 10.8 1.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5521) LMBR1 PF04791.16 ORY40435.1 - 3.9e-35 121.7 12.3 1.5e-22 80.2 0.0 2.1 1 1 1 2 2 2 2 LMBR1-like membrane protein Cpn60_TCP1 PF00118.24 ORY40436.1 - 4.7e-158 526.8 14.4 5.3e-158 526.7 14.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SAS-6_N PF16531.5 ORY40437.1 - 5.4e-10 39.7 0.1 1.3e-09 38.5 0.1 1.7 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal Fib_alpha PF08702.10 ORY40437.1 - 0.2 11.9 10.6 5 7.3 0.0 3.3 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family Mt_ATP-synt_D PF05873.12 ORY40437.1 - 1 9.2 8.8 4.2 7.2 0.4 3.6 2 1 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) DUF1664 PF07889.12 ORY40437.1 - 2 8.5 12.2 0.92 9.6 0.5 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) RUN PF02759.19 ORY40437.1 - 2.7 7.9 7.2 13 5.7 7.2 2.2 1 1 0 1 1 1 0 RUN domain DUF2120 PF09893.9 ORY40437.1 - 7.5 6.7 7.6 9.8 6.3 1.7 2.9 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) LSM PF01423.22 ORY40438.1 - 4e-17 61.7 0.1 4.5e-17 61.5 0.1 1.0 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 ORY40438.1 - 0.0018 17.9 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 Hfq protein HSF_DNA-bind PF00447.17 ORY40439.1 - 4.3e-32 110.6 0.6 5e-32 110.4 0.6 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding GPI2 PF06432.11 ORY40440.1 - 1.5e-67 228.0 9.9 2.2e-53 181.5 4.9 2.0 1 1 1 2 2 2 2 Phosphatidylinositol N-acetylglucosaminyltransferase TMEM40 PF15817.5 ORY40440.1 - 0.12 12.1 0.3 0.23 11.2 0.3 1.5 1 0 0 1 1 1 0 Transmembrane protein 40 family NMN_transporter PF04973.12 ORY40440.1 - 1.6 8.7 5.7 9 6.2 0.5 2.4 1 1 0 2 2 2 0 Nicotinamide mononucleotide transporter PRA1 PF03208.19 ORY40440.1 - 2.2 7.9 11.1 0.55 9.8 4.2 2.1 2 0 0 2 2 2 0 PRA1 family protein zf-C2H2 PF00096.26 ORY40441.1 - 3.8e-05 23.9 10.8 0.0033 17.8 6.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY40441.1 - 0.0014 19.3 10.3 0.0073 17.1 4.3 2.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY40441.1 - 0.096 13.0 7.0 0.75 10.1 2.5 2.3 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 ORY40441.1 - 9.2 6.9 10.9 14 6.3 2.2 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-H2C2_2 PF13465.6 ORY40442.1 - 0.0073 16.7 0.7 0.0073 16.7 0.7 2.2 2 1 0 2 2 2 1 Zinc-finger double domain zf-FCS PF06467.14 ORY40442.1 - 0.023 14.6 0.2 0.045 13.7 0.2 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-C2H2_6 PF13912.6 ORY40442.1 - 0.18 11.9 0.5 0.18 11.9 0.5 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY40442.1 - 0.24 11.9 1.5 0.24 11.9 1.5 2.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY40446.1 - 0.0048 17.3 0.6 0.0084 16.5 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger double domain zf-C2H2 PF00096.26 ORY40446.1 - 0.056 13.9 3.8 3.1 8.4 0.6 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2 PF00096.26 ORY40447.1 - 0.0013 19.1 5.5 0.0013 19.1 5.5 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY40447.1 - 0.011 16.5 4.4 0.011 16.5 4.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY40447.1 - 0.024 14.9 0.4 0.024 14.9 0.4 1.8 2 1 0 2 2 2 0 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 ORY40447.1 - 0.79 10.3 11.5 1 9.9 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain F-box-like PF12937.7 ORY40448.1 - 0.0013 18.6 0.1 0.0032 17.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like DEAD PF00270.29 ORY40449.1 - 1.7e-48 164.7 0.0 2.5e-48 164.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY40449.1 - 7.8e-31 106.7 0.0 2.7e-30 105.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 ORY40449.1 - 0.0053 16.1 0.0 0.0092 15.4 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 ORY40449.1 - 0.0059 16.6 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY40449.1 - 0.073 13.4 0.2 1.9 8.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain Mak10 PF04112.13 ORY40450.1 - 5.9e-22 78.0 0.1 4.2e-20 71.9 0.0 2.5 1 1 1 2 2 2 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase UPF0181 PF03701.14 ORY40450.1 - 0.033 13.8 0.4 0.092 12.4 0.4 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) GntP_permease PF02447.16 ORY40451.1 - 0.054 12.2 0.4 0.059 12.1 0.4 1.0 1 0 0 1 1 1 0 GntP family permease NADH_B2 PF14813.6 ORY40451.1 - 0.11 12.3 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 LrgB PF04172.16 ORY40452.1 - 1.9 8.0 7.8 1.4 8.4 0.4 2.4 2 0 0 2 2 2 0 LrgB-like family SNF2_N PF00176.23 ORY40453.1 - 6e-58 196.2 0.0 1.1e-57 195.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF3535 PF12054.8 ORY40453.1 - 2.8e-56 191.6 0.0 1.6e-45 156.2 0.0 5.1 5 0 0 5 5 5 2 Domain of unknown function (DUF3535) Helicase_C PF00271.31 ORY40453.1 - 1.1e-16 61.1 0.0 2.6e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 ORY40453.1 - 6.9e-09 35.2 18.5 0.022 15.0 0.2 9.1 9 1 1 10 10 10 2 HEAT repeat HEAT_2 PF13646.6 ORY40453.1 - 3.8e-05 24.0 2.0 0.02 15.3 0.2 4.5 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 ORY40453.1 - 0.00014 22.3 10.9 0.39 11.3 0.0 7.1 6 2 1 7 7 7 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 ORY40453.1 - 0.00052 20.6 0.0 0.27 11.9 0.0 3.6 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region IL31 PF15209.6 ORY40453.1 - 0.059 13.1 0.1 16 5.3 0.0 3.2 3 0 0 3 3 3 0 Interleukin 31 HEAT PF02985.22 ORY40454.1 - 4.1e-09 35.9 0.0 0.31 11.4 0.0 5.7 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 ORY40454.1 - 4e-07 30.2 0.0 0.00022 21.3 0.0 2.6 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Pkinase PF00069.25 ORY40454.1 - 0.00011 21.7 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY40454.1 - 0.00016 21.1 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 ORY40454.1 - 0.0015 18.9 0.0 0.82 10.1 0.0 3.2 1 1 2 3 3 3 2 HEAT repeats RAP1 PF07218.11 ORY40454.1 - 3.5 5.8 6.2 5.3 5.2 6.2 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) 7tm_1 PF00001.21 ORY40455.1 - 0.00067 19.1 18.2 0.0012 18.3 18.2 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF2637 PF10935.8 ORY40455.1 - 0.81 9.6 6.4 1.7 8.5 3.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2637) cNMP_binding PF00027.29 ORY40457.1 - 3.4e-41 139.2 1.6 8.3e-17 61.1 0.1 3.3 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 ORY40457.1 - 0.0046 16.6 0.4 0.87 9.4 0.2 2.5 2 0 0 2 2 2 2 Cupin domain EMG1 PF03587.14 ORY40457.1 - 0.065 12.9 0.4 0.79 9.3 0.1 2.4 2 0 0 2 2 2 0 EMG1/NEP1 methyltransferase Spc24 PF08286.11 ORY40457.1 - 0.26 11.6 2.9 1.5 9.1 0.4 2.7 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 SlyX PF04102.12 ORY40457.1 - 0.77 10.4 2.8 0.57 10.8 0.2 2.1 2 0 0 2 2 2 0 SlyX HAP1_N PF04849.13 ORY40457.1 - 2 7.6 8.0 0.5 9.5 1.4 2.6 2 1 1 3 3 3 0 HAP1 N-terminal conserved region Vasohibin PF14822.6 ORY40458.1 - 1.5e-18 66.9 0.0 3e-18 65.9 0.0 1.4 1 1 1 2 2 2 1 Vasohibin DUF935 PF06074.12 ORY40459.1 - 0.29 9.8 2.3 0.51 9.0 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Pkinase PF00069.25 ORY40460.1 - 1.2e-41 142.9 0.0 1.7e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY40460.1 - 4.9e-41 140.7 0.0 1.7e-40 139.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY40460.1 - 4.1e-05 23.6 0.1 0.00011 22.3 0.1 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY40460.1 - 0.0071 15.7 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY40460.1 - 0.012 14.6 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 ORY40460.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4031 PF13223.6 ORY40461.1 - 0.076 13.2 0.1 0.13 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4031) FlaG PF03646.15 ORY40462.1 - 0.39 10.9 6.3 0.48 10.6 6.3 1.1 1 0 0 1 1 1 0 FlaG protein YfhO PF09586.10 ORY40462.1 - 2.5 6.2 9.9 2.7 6.1 9.9 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Pkinase PF00069.25 ORY40463.1 - 2e-43 148.7 0.0 2.9e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY40463.1 - 2.1e-38 132.1 0.0 7.3e-38 130.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Sel1 PF08238.12 ORY40463.1 - 5.9e-18 64.9 0.1 5.3e-08 33.3 0.0 2.8 2 0 0 2 2 2 2 Sel1 repeat APH PF01636.23 ORY40463.1 - 0.0001 22.4 0.1 0.00019 21.4 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family TPR_6 PF13174.6 ORY40463.1 - 0.00021 21.7 0.0 0.014 16.0 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Kinase-like PF14531.6 ORY40463.1 - 0.00048 19.5 0.0 0.00076 18.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY40463.1 - 0.032 13.2 0.0 0.06 12.3 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain TPR_11 PF13414.6 ORY40463.1 - 0.038 13.7 0.8 35 4.2 0.1 3.6 3 0 0 3 3 3 0 TPR repeat bZIP_1 PF00170.21 ORY40464.1 - 3.2e-05 23.9 2.5 3.2e-05 23.9 2.5 4.8 5 0 0 5 5 5 1 bZIP transcription factor TSC22 PF01166.18 ORY40464.1 - 0.00085 19.6 12.3 0.15 12.4 0.0 5.9 4 1 2 6 6 6 2 TSC-22/dip/bun family Shugoshin_N PF07558.11 ORY40464.1 - 0.0021 17.9 9.0 0.81 9.6 0.3 4.2 4 0 0 4 4 4 2 Shugoshin N-terminal coiled-coil region SlyX PF04102.12 ORY40464.1 - 1.2 9.8 8.4 3.2 8.4 0.0 4.7 5 0 0 5 5 5 0 SlyX JIP_LZII PF16471.5 ORY40464.1 - 6.8 6.9 9.1 2 8.6 3.0 3.3 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II bZIP_1 PF00170.21 ORY40466.1 - 6.4e-07 29.4 1.3 6.4e-07 29.4 1.3 2.7 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 ORY40466.1 - 0.016 15.3 3.3 0.016 15.3 3.3 2.8 3 0 0 3 3 3 0 Basic region leucine zipper SLX9 PF15341.6 ORY40466.1 - 0.019 15.4 1.1 0.019 15.4 1.1 1.7 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 DUF3553 PF12073.8 ORY40466.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3553) OmpH PF03938.14 ORY40466.1 - 0.4 11.0 4.5 0.91 9.9 4.5 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SNF2_N PF00176.23 ORY40467.1 - 2.9e-25 88.7 0.8 7.1e-25 87.5 0.2 2.1 2 1 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 ORY40467.1 - 1.8e-08 34.1 7.1 3.8e-08 33.1 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 ORY40467.1 - 1.6e-07 31.5 2.2 2e-07 31.2 0.2 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 ORY40467.1 - 5.7e-06 26.2 7.1 1.3e-05 25.1 7.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 ORY40467.1 - 1.6e-05 25.1 9.0 1.6e-05 25.1 9.0 2.4 2 0 0 2 2 2 1 Ring finger domain Helicase_C PF00271.31 ORY40467.1 - 4e-05 23.9 0.1 0.13 12.6 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 ORY40467.1 - 0.00026 20.8 7.0 0.00075 19.3 7.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY40467.1 - 0.00065 19.5 8.2 0.0017 18.2 8.2 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 ORY40467.1 - 0.0012 18.7 9.2 0.0012 18.7 9.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY40467.1 - 0.0015 18.5 8.2 0.0052 16.8 8.2 2.0 1 0 0 1 1 1 1 RING-type zinc-finger DEAD PF00270.29 ORY40467.1 - 0.003 17.3 0.3 0.36 10.6 0.3 2.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_11 PF17123.5 ORY40467.1 - 0.0037 17.0 1.3 0.0037 17.0 1.3 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_6 PF14835.6 ORY40467.1 - 0.0071 16.2 3.6 0.025 14.4 3.6 2.0 1 0 0 1 1 1 1 zf-RING of BARD1-type protein bZIP_1 PF00170.21 ORY40468.1 - 3.2e-05 23.9 9.4 3.2e-05 23.9 9.4 3.1 2 1 1 3 3 3 2 bZIP transcription factor CCD48 PF15799.5 ORY40468.1 - 0.00014 20.4 1.7 0.0002 19.8 1.7 1.2 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 48 DUF4662 PF15578.6 ORY40468.1 - 0.054 13.3 1.3 0.08 12.7 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) TSC22 PF01166.18 ORY40468.1 - 0.64 10.4 3.7 5.3 7.4 0.4 3.3 2 1 1 3 3 3 0 TSC-22/dip/bun family DivIC PF04977.15 ORY40468.1 - 0.66 9.8 3.2 0.57 10.0 0.7 2.1 1 1 1 2 2 2 0 Septum formation initiator bZIP_2 PF07716.15 ORY40468.1 - 1 9.5 17.1 0.25 11.5 2.9 3.2 3 0 0 3 3 3 0 Basic region leucine zipper Methyltransf_16 PF10294.9 ORY40469.1 - 2.5e-19 69.7 0.0 3.5e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_31 PF13847.6 ORY40469.1 - 7e-08 32.4 0.0 8.3e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY40469.1 - 1.4e-05 24.8 0.0 1.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ORY40469.1 - 4.1e-05 24.2 0.0 6.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY40469.1 - 0.0022 18.7 0.0 0.0035 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ORY40469.1 - 0.0022 17.4 0.1 0.0027 17.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.15 ORY40469.1 - 0.033 13.5 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G DUF5522 PF17653.1 ORY40470.1 - 4.3e-21 74.6 6.0 8.2e-21 73.7 6.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5522) Diphthami_syn_2 PF01902.17 ORY40470.1 - 1.1e-05 25.0 0.0 3.2e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Diphthamide synthase Ank_2 PF12796.7 ORY40471.1 - 1.5e-25 89.6 11.5 5.2e-08 33.4 0.7 4.8 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY40471.1 - 1.3e-12 47.9 14.5 0.00042 20.8 0.1 6.5 3 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY40471.1 - 1.7e-12 46.3 19.1 0.19 12.4 0.0 9.5 9 1 1 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 ORY40471.1 - 8.3e-11 41.9 20.7 0.042 14.2 0.3 9.1 2 2 8 10 10 10 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY40471.1 - 6.1e-07 29.6 23.3 0.59 10.7 0.3 8.4 8 2 2 10 10 10 4 Ankyrin repeat MRJP PF03022.16 ORY40471.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Major royal jelly protein GPP34 PF05719.11 ORY40472.1 - 0.087 12.9 0.0 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 Golgi phosphoprotein 3 (GPP34) CDC45 PF02724.14 ORY40475.1 - 0.25 9.6 15.9 0.48 8.6 15.9 1.5 1 0 0 1 1 1 0 CDC45-like protein MDM10 PF12519.8 ORY40475.1 - 5.7 5.7 7.5 12 4.7 7.5 1.5 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 IGFBP PF00219.18 ORY40477.1 - 0.0008 20.0 13.9 0.36 11.5 0.5 4.4 4 0 0 4 4 4 3 Insulin-like growth factor binding protein CBM_1 PF00734.18 ORY40477.1 - 0.19 11.7 18.4 0.1 12.6 1.2 4.5 4 0 0 4 4 4 0 Fungal cellulose binding domain Inhibitor_I36 PF03995.13 ORY40477.1 - 0.73 9.8 0.0 0.73 9.8 0.0 2.8 4 0 0 4 4 4 0 Peptidase inhibitor family I36 NTF2 PF02136.20 ORY40478.1 - 4.7e-34 117.5 0.0 5.3e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain HAUS6_N PF14661.6 ORY40479.1 - 7.2e-27 94.4 0.5 9.9e-27 94.0 0.5 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Fic_N PF13784.6 ORY40479.1 - 0.015 15.4 0.9 0.04 14.0 0.7 1.8 1 1 1 2 2 2 0 Fic/DOC family N-terminal Methyltransf_22 PF13383.6 ORY40479.1 - 0.027 14.0 0.3 0.068 12.7 0.1 1.6 1 1 1 2 2 2 0 Methyltransferase domain Hexokinase_2 PF03727.16 ORY40479.1 - 0.032 13.7 1.4 0.06 12.8 1.4 1.4 1 0 0 1 1 1 0 Hexokinase NST1 PF13945.6 ORY40479.1 - 0.06 13.5 0.5 0.11 12.5 0.5 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator TRAM_LAG1_CLN8 PF03798.16 ORY40480.1 - 2.4e-21 76.4 14.0 3.3e-21 75.9 14.0 1.2 1 0 0 1 1 1 1 TLC domain FA_hydroxylase PF04116.13 ORY40481.1 - 4.8e-14 52.9 16.0 4.8e-14 52.9 16.0 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Sin_N PF04801.13 ORY40482.1 - 9e-31 107.5 0.0 1.2e-30 107.1 0.0 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region DUF3597 PF12200.8 ORY40482.1 - 0.3 11.6 2.3 0.58 10.7 2.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) G-patch PF01585.23 ORY40483.1 - 3.5e-09 36.4 1.4 5.1e-09 35.9 0.3 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 ORY40483.1 - 0.00093 19.2 0.1 0.01 15.9 0.2 2.5 2 0 0 2 2 2 1 G-patch domain FAD_binding_4 PF01565.23 ORY40484.1 - 2.4e-57 192.6 2.4 8.1e-28 96.9 0.2 2.5 2 0 0 2 2 2 2 FAD binding domain BBE PF08031.12 ORY40484.1 - 5.5e-09 36.0 0.2 5.7e-07 29.5 0.0 2.6 2 0 0 2 2 2 1 Berberine and berberine like SNAD3 PF18749.1 ORY40484.1 - 5.3e-05 22.5 0.9 0.19 10.9 0.0 2.3 2 0 0 2 2 2 2 Secreted Novel AID/APOBEC-like Deaminase 3 DUF4532 PF15046.6 ORY40484.1 - 0.0029 16.8 0.0 2.5 7.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF4532) DUF3525 PF12039.8 ORY40484.1 - 0.034 12.9 0.0 7.3 5.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3525) Cytidylate_kin PF02224.18 ORY40484.1 - 0.15 11.8 0.1 19 4.9 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase MFS_1 PF07690.16 ORY40485.1 - 4e-33 114.8 68.3 7.2e-17 61.3 23.2 4.0 1 1 2 3 3 3 3 Major Facilitator Superfamily UNC-93 PF05978.16 ORY40485.1 - 2.4e-24 85.9 41.8 4.9e-14 52.3 10.3 4.9 3 2 0 3 3 3 2 Ion channel regulatory protein UNC-93 Peptidase_C14 PF00656.22 ORY40486.1 - 6e-44 150.9 0.1 7.9e-44 150.5 0.1 1.1 1 0 0 1 1 1 1 Caspase domain RST PF12174.8 ORY40486.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain RRM_1 PF00076.22 ORY40487.1 - 4.1e-06 26.5 0.0 7.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MRNIP PF15749.5 ORY40488.1 - 1.8e-21 76.9 15.2 8.2e-21 74.8 15.2 2.3 1 1 0 1 1 1 1 MRN-interacting protein zf-MIZ PF02891.20 ORY40488.1 - 0.0037 17.0 3.2 0.0085 15.8 3.2 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Sec23_Sec24 PF04810.15 ORY40488.1 - 0.01 15.8 3.8 0.03 14.4 3.8 1.8 1 1 0 1 1 1 0 Sec23/Sec24 zinc finger Nuc_deoxyri_tr2 PF15891.5 ORY40488.1 - 0.027 14.8 0.2 0.052 13.9 0.2 1.5 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase like PHM7_cyt PF14703.6 ORY40488.1 - 0.05 13.8 2.0 0.15 12.3 0.7 2.2 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter FlhC PF05280.11 ORY40488.1 - 0.066 12.9 1.6 0.097 12.4 1.6 1.2 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) C1_1 PF00130.22 ORY40488.1 - 0.54 10.2 4.4 0.91 9.5 4.4 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ima1_N PF09779.9 ORY40488.1 - 2.4 9.0 12.4 5.8 7.8 12.1 1.9 1 1 0 1 1 1 0 Ima1 N-terminal domain Gram_pos_anchor PF00746.21 ORY40489.1 - 0.04 13.9 1.2 0.04 13.9 1.2 2.4 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Trp_oprn_chp PF09534.10 ORY40489.1 - 0.24 11.2 4.9 4.6 7.0 0.3 2.3 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Hepar_II_III PF07940.13 ORY40490.1 - 9.7e-19 67.9 0.6 1.7e-18 67.1 0.6 1.3 1 0 0 1 1 1 1 Heparinase II/III-like protein DUF4962 PF16332.5 ORY40490.1 - 5.4e-15 54.9 0.1 5.4e-15 54.9 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4962) PALP PF00291.25 ORY40491.1 - 3e-47 161.4 0.1 3.5e-47 161.3 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ndc1_Nup PF09531.10 ORY40492.1 - 1.5e-18 66.9 0.0 1.6e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Ndc1_Nup PF09531.10 ORY40493.1 - 1.2e-11 44.1 14.0 1.2e-11 44.1 14.0 1.8 1 1 1 2 2 2 1 Nucleoporin protein Ndc1-Nup DUF2516 PF10724.9 ORY40493.1 - 0.81 10.0 3.6 0.23 11.8 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2516) UQ_con PF00179.26 ORY40495.1 - 2.5e-25 88.8 0.0 4.8e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 ORY40495.1 - 0.014 15.3 0.2 0.048 13.5 0.2 1.9 1 1 0 1 1 1 0 UEV domain Dynein_AAA_lid PF17852.1 ORY40496.1 - 0.076 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain PTPLA PF04387.14 ORY40496.1 - 1.4 8.7 15.0 0.52 10.0 0.3 3.4 1 1 2 3 3 3 0 Protein tyrosine phosphatase-like protein, PTPLA Snf7 PF03357.21 ORY40497.1 - 4.2e-23 81.8 12.4 9.7e-23 80.6 12.4 1.6 1 0 0 1 1 1 1 Snf7 ZapB PF06005.12 ORY40497.1 - 0.19 12.2 10.6 0.048 14.1 2.5 2.8 2 1 0 2 2 2 0 Cell division protein ZapB DUF1542 PF07564.11 ORY40497.1 - 0.27 11.4 4.0 3.7 7.7 0.1 3.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) DUF3080 PF11279.8 ORY40497.1 - 0.37 10.0 6.8 0.089 12.0 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3080) YabA PF06156.13 ORY40497.1 - 9.9 6.9 9.6 11 6.7 2.8 2.5 1 1 1 2 2 2 0 Initiation control protein YabA HOOK PF05622.12 ORY40500.1 - 0.74 7.9 43.8 0.041 12.1 28.2 2.1 1 1 1 2 2 2 0 HOOK protein FUSC PF04632.12 ORY40500.1 - 1.2 7.6 22.9 0.23 10.0 18.2 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family ArAE_2_N PF10337.9 ORY40500.1 - 1.4 7.8 11.3 2.7 7.0 11.3 1.5 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal EzrA PF06160.12 ORY40500.1 - 2.4 6.2 29.2 4.8 5.2 24.1 2.7 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA Golgin_A5 PF09787.9 ORY40500.1 - 4.4 6.7 47.0 0.15 11.5 10.3 3.3 1 1 2 3 3 3 0 Golgin subfamily A member 5 YabA PF06156.13 ORY40500.1 - 6.2 7.5 27.9 4.7 7.9 1.6 4.7 1 1 4 5 5 5 0 Initiation control protein YabA DUF812 PF05667.11 ORY40500.1 - 9.8 4.9 40.7 39 2.9 39.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) F-box-like PF12937.7 ORY40502.1 - 2.2e-09 37.1 3.0 4.1e-09 36.2 3.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY40502.1 - 3.8e-07 29.8 0.6 6.9e-07 29.0 0.6 1.4 1 0 0 1 1 1 1 F-box domain RPA_interact_N PF14766.6 ORY40502.1 - 0.013 15.1 0.7 0.026 14.1 0.7 1.5 1 0 0 1 1 1 0 Replication protein A interacting N-terminal Serglycin PF04360.12 ORY40502.1 - 0.15 12.0 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Serglycin Peptidase_M1 PF01433.20 ORY40504.1 - 2.2e-54 184.4 2.8 3.2e-54 183.8 2.8 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 ORY40504.1 - 2.5e-23 83.2 0.0 5.3e-23 82.2 0.0 1.6 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 ORY40504.1 - 6.1e-20 72.0 0.0 1.4e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 ERAP1-like C-terminal domain LRR_4 PF12799.7 ORY40505.1 - 4.9e-17 61.8 31.5 5.2e-05 23.5 0.1 9.6 6 3 3 10 10 10 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY40505.1 - 1.1e-05 25.0 26.9 0.0018 18.0 3.7 6.0 3 3 3 6 6 6 4 Leucine rich repeat LRR_9 PF14580.6 ORY40505.1 - 1.6e-05 24.5 10.1 0.0057 16.2 2.3 3.3 1 1 3 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.6 ORY40505.1 - 0.81 9.9 11.8 34 4.8 0.0 6.5 7 0 0 7 7 7 0 Leucine Rich repeat IDO PF01231.18 ORY40506.1 - 0.0083 14.9 1.3 0.01 14.6 0.0 1.7 3 0 0 3 3 3 1 Indoleamine 2,3-dioxygenase MADF_DNA_bdg PF10545.9 ORY40506.1 - 0.042 14.2 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like MFS_1 PF07690.16 ORY40508.1 - 4.5e-21 75.2 31.5 4.5e-21 75.2 31.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY40508.1 - 1e-10 41.5 22.9 1.3e-09 38.0 13.1 3.8 2 2 1 3 3 3 2 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 ORY40508.1 - 0.013 14.4 17.5 0.0075 15.2 5.4 2.8 2 1 0 2 2 2 0 MFS_1 like family DUF2374 PF09574.10 ORY40508.1 - 0.049 13.5 0.2 0.049 13.5 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (Duf2374) AAA_33 PF13671.6 ORY40509.1 - 0.015 15.5 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ORY40509.1 - 0.023 14.9 0.0 0.034 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ORY40509.1 - 0.042 14.4 0.0 0.052 14.1 0.0 1.3 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 ORY40509.1 - 0.048 13.6 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 ORY40509.1 - 0.079 13.5 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 ORY40510.1 - 8.2e-13 48.6 15.7 0.0012 19.6 1.9 7.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY40510.1 - 8.1e-07 29.3 0.1 0.00063 20.0 0.2 3.6 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY40510.1 - 0.015 14.6 0.1 0.2 11.0 0.0 2.2 1 1 1 2 2 2 0 WD40-like domain Ribosomal_L33 PF00471.20 ORY40511.1 - 8.2e-10 39.0 0.0 1.1e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 YchF-GTPase_C PF06071.13 ORY40512.1 - 3.2e-37 126.6 0.2 1.9e-36 124.1 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 ORY40512.1 - 6.8e-23 80.9 0.0 2e-22 79.4 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY40512.1 - 8.1e-08 31.9 0.0 1.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORY40512.1 - 0.00046 20.3 0.3 0.24 11.5 0.1 3.2 2 1 1 3 3 3 2 Dynamin family ABC_tran PF00005.27 ORY40512.1 - 0.12 12.9 0.0 0.36 11.3 0.0 1.8 2 0 0 2 2 2 0 ABC transporter Phage_holin_3_6 PF07332.11 ORY40513.1 - 9.6e-05 22.4 0.9 0.0001 22.3 0.9 1.0 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III SLATT_fungal PF18142.1 ORY40513.1 - 0.0016 18.4 0.4 0.002 18.1 0.4 1.1 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Gram_pos_anchor PF00746.21 ORY40513.1 - 0.0081 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 LPXTG cell wall anchor motif DUF4381 PF14316.6 ORY40513.1 - 0.083 13.1 0.2 0.094 13.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF2206 PF09971.9 ORY40513.1 - 0.097 11.4 0.2 0.11 11.3 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) DUF3188 PF11384.8 ORY40513.1 - 0.1 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) Phage_holin_3_6 PF07332.11 ORY40514.1 - 0.037 14.1 0.2 0.037 14.1 0.2 1.7 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Gram_pos_anchor PF00746.21 ORY40514.1 - 1.5 8.8 6.1 0.19 11.7 0.5 2.6 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Mannosyl_trans PF05007.13 ORY40515.1 - 1.7e-79 267.4 20.0 1.3e-77 261.2 20.0 2.1 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 ORY40515.1 - 4.1e-13 49.1 16.4 1.3e-12 47.5 16.4 1.7 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 ORY40515.1 - 0.003 17.3 9.7 0.003 17.3 9.7 3.4 2 2 0 2 2 2 1 Glycosyltransferase family 87 ALG3 PF05208.13 ORY40515.1 - 0.059 12.8 16.0 2.6 7.4 6.2 3.5 3 1 0 3 3 3 0 ALG3 protein Corona_nucleoca PF00937.18 ORY40515.1 - 0.81 8.7 4.3 1.3 8.0 4.3 1.2 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF5029 PF16432.5 ORY40516.1 - 0.12 12.0 4.1 1.1 8.8 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5029) Phage_holin_3_6 PF07332.11 ORY40517.1 - 0.084 12.9 0.3 0.23 11.5 0.3 1.7 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Gram_pos_anchor PF00746.21 ORY40517.1 - 0.15 12.0 0.2 0.15 12.0 0.2 2.5 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Shadoo PF14999.6 ORY40517.1 - 0.67 10.1 5.9 1.9 8.6 0.6 2.8 2 1 1 3 3 3 0 Shadow of prion protein, neuroprotective CATSPERG PF15064.6 ORY40518.1 - 7.4e-16 57.2 0.0 1.1e-13 50.0 0.0 2.2 2 0 0 2 2 2 2 Cation channel sperm-associated protein subunit gamma DUF1754 PF08555.10 ORY40520.1 - 3.9e-07 30.8 15.6 3.9e-07 30.8 15.6 2.3 1 1 1 2 2 2 1 Eukaryotic family of unknown function (DUF1754) HemY_N PF07219.13 ORY40520.1 - 0.17 12.1 1.5 0.2 11.8 1.5 1.1 1 0 0 1 1 1 0 HemY protein N-terminus DUF5384 PF17358.2 ORY40521.1 - 0.088 12.8 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5384) DAP10 PF07213.11 ORY40522.1 - 0.074 13.0 0.4 0.16 11.9 0.4 1.5 1 0 0 1 1 1 0 DAP10 membrane protein Adenine_glyco PF03352.13 ORY40523.1 - 4.8e-75 251.2 0.0 7.2e-75 250.6 0.0 1.2 1 0 0 1 1 1 1 Methyladenine glycosylase AA_permease_2 PF13520.6 ORY40524.1 - 5e-13 48.7 44.2 7.8e-13 48.0 44.2 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY40524.1 - 5.5e-10 38.4 36.4 8.1e-10 37.9 36.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF218 PF02698.17 ORY40524.1 - 0.18 11.8 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 DUF218 domain cNMP_binding PF00027.29 ORY40526.1 - 9.2e-08 32.1 0.1 1.3e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Cupin_3 PF05899.12 ORY40526.1 - 0.033 13.9 0.0 0.075 12.7 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF861) DUF2244 PF10003.9 ORY40527.1 - 0.16 11.6 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) EphA2_TM PF14575.6 ORY40531.1 - 0.13 13.2 0.0 0.23 12.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LMBR1 PF04791.16 ORY40531.1 - 0.15 10.9 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Troponin-I_N PF11636.8 ORY40532.1 - 0.021 14.8 0.1 0.043 13.8 0.1 1.4 1 0 0 1 1 1 0 Troponin I residues 1-32 Cadherin_C_2 PF16492.5 ORY40533.1 - 0.00045 20.9 0.1 0.08 13.7 0.2 2.5 2 0 0 2 2 2 1 Cadherin cytoplasmic C-terminal EphA2_TM PF14575.6 ORY40533.1 - 0.0012 19.7 0.0 0.42 11.5 0.0 2.6 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 ORY40533.1 - 0.0014 18.6 0.7 0.055 13.4 0.1 2.6 2 0 0 2 2 2 1 TMEM154 protein family Protocadherin PF08374.11 ORY40533.1 - 0.0017 18.4 0.0 0.038 14.0 0.0 2.2 2 0 0 2 2 2 1 Protocadherin Shisa PF13908.6 ORY40533.1 - 0.011 16.0 0.6 0.11 12.7 0.5 2.3 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Orf78 PF06024.12 ORY40533.1 - 0.014 15.6 0.2 0.56 10.5 0.1 2.5 2 0 0 2 2 2 0 Orf78 (ac78) Oxidored_q2 PF00420.24 ORY40533.1 - 0.036 13.7 0.6 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L LapA_dom PF06305.11 ORY40533.1 - 0.18 11.6 1.8 0.87 9.5 0.1 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DOPA_dioxygen PF08883.11 ORY40534.1 - 1.1e-15 57.7 0.1 1.7e-15 57.1 0.1 1.3 1 1 0 1 1 1 1 Dopa 4,5-dioxygenase family DOPA_dioxygen PF08883.11 ORY40535.1 - 4.5e-23 81.5 0.1 5.8e-23 81.1 0.1 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family TMEM154 PF15102.6 ORY40536.1 - 0.026 14.4 0.2 0.037 13.9 0.2 1.2 1 0 0 1 1 1 0 TMEM154 protein family Trep_Strep PF09605.10 ORY40536.1 - 0.04 13.9 0.1 0.055 13.5 0.1 1.2 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Herpes_gE PF02480.16 ORY40536.1 - 0.099 11.4 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E ArAE_2_N PF10337.9 ORY40537.1 - 0.038 13.0 0.1 0.038 13.0 0.1 2.8 2 1 1 3 3 3 0 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 ORY40538.1 - 0.00025 21.2 13.0 0.00028 21.0 12.1 1.5 1 1 0 1 1 1 1 Fusaric acid resistance protein-like ArAE_1 PF06081.11 ORY40538.1 - 0.014 15.6 1.5 0.014 15.6 1.5 1.6 2 0 0 2 2 2 0 Aromatic acid exporter family member 1 Mid2 PF04478.12 ORY40540.1 - 0.00012 22.0 2.3 0.00035 20.4 2.3 1.8 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Herpes_gE PF02480.16 ORY40540.1 - 0.037 12.8 0.3 0.037 12.8 0.3 2.4 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E MAP70 PF07058.11 ORY40542.1 - 0.45 9.2 5.2 0.79 8.4 5.2 1.3 1 0 0 1 1 1 0 Microtubule-associated protein 70 DUF4229 PF14012.6 ORY40543.1 - 0.013 15.5 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF4328 PF14219.6 ORY40543.1 - 0.035 13.6 0.0 0.74 9.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) DUF456 PF04306.13 ORY40543.1 - 0.037 14.3 0.3 0.062 13.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) LapA_dom PF06305.11 ORY40543.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF4448 PF14610.6 ORY40543.1 - 0.13 12.0 0.1 0.24 11.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) TMEM154 PF15102.6 ORY40544.1 - 0.039 13.8 0.6 0.039 13.8 0.6 3.0 2 1 0 3 3 3 0 TMEM154 protein family Orf78 PF06024.12 ORY40544.1 - 0.098 13.0 1.0 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 Orf78 (ac78) Adeno_E3_CR2 PF02439.15 ORY40544.1 - 0.22 11.3 0.1 0.46 10.3 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SR-25 PF10500.9 ORY40544.1 - 7.7 6.0 13.0 3.7 7.1 6.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CBM_5_12 PF02839.14 ORY40545.1 - 0.016 15.8 1.9 0.053 14.1 1.9 2.0 1 0 0 1 1 1 0 Carbohydrate binding domain PRR18 PF15671.5 ORY40545.1 - 0.05 13.5 1.7 0.071 13.0 1.7 1.2 1 0 0 1 1 1 0 Proline-rich protein family 18 DUF3439 PF11921.8 ORY40546.1 - 1.3 9.0 20.6 13 5.7 18.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) HHV-5_US34A PF17087.5 ORY40547.1 - 0.15 12.2 1.2 0.18 12.0 0.9 1.3 1 1 0 1 1 1 0 Herpesvirus US34A protein family Nuc_sug_transp PF04142.15 ORY40548.1 - 6.8e-08 32.0 11.1 7.6e-08 31.9 11.1 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter Myelin_PLP PF01275.19 ORY40548.1 - 0.084 12.7 4.8 0.12 12.2 4.8 1.2 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) Got1 PF04178.12 ORY40548.1 - 0.16 12.4 13.1 0.3 11.5 13.1 1.4 1 1 0 1 1 1 0 Got1/Sft2-like family YoaP PF14268.6 ORY40548.1 - 0.71 9.4 2.2 9.9 5.8 0.1 2.3 2 0 0 2 2 2 0 YoaP-like DUF2975 PF11188.8 ORY40548.1 - 1 9.3 10.1 0.96 9.3 8.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) DUF3980 PF13140.6 ORY40548.1 - 1.2 9.7 11.6 28 5.2 7.4 3.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3980) DUF2157 PF09925.9 ORY40548.1 - 2.4 7.9 10.6 2.4 7.9 9.6 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) YrhK PF14145.6 ORY40548.1 - 2.9 7.8 12.5 7.9 6.4 3.1 3.1 2 2 1 3 3 3 0 YrhK-like protein COX14 PF14880.6 ORY40549.1 - 0.093 12.6 0.1 1.8 8.5 0.0 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c assembly PPL4 PF18188.1 ORY40550.1 - 7.7e-07 29.2 0.1 1.1e-06 28.7 0.1 1.3 1 0 0 1 1 1 1 Prim-pol 4 YxiJ PF14176.6 ORY40550.1 - 0.05 14.1 0.1 0.094 13.2 0.1 1.4 1 0 0 1 1 1 0 YxiJ-like protein zf-C2H2_12 PF18658.1 ORY40551.1 - 0.061 12.9 0.6 0.17 11.5 0.6 1.8 1 0 0 1 1 1 0 Zinc-finger C2H2-type SET PF00856.28 ORY40552.1 - 0.024 15.0 0.0 0.13 12.6 0.0 2.0 1 1 0 1 1 1 0 SET domain Cyt-b5 PF00173.28 ORY40553.1 - 9.1e-05 22.5 0.0 0.0011 19.0 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain LRR_8 PF13855.6 ORY40558.1 - 3.2e-07 30.0 15.4 0.00034 20.3 0.4 4.9 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.6 ORY40558.1 - 2.5e-06 27.1 24.4 0.11 12.6 0.0 7.6 8 0 0 8 8 8 4 Leucine Rich repeat LRR_1 PF00560.33 ORY40558.1 - 0.00017 21.6 19.2 16 6.5 0.0 8.7 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_4 PF12799.7 ORY40558.1 - 0.022 15.2 22.3 0.029 14.8 2.2 5.7 5 1 0 6 6 6 0 Leucine Rich repeats (2 copies) YjeJ PF15922.5 ORY40558.1 - 0.084 12.1 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 YjeJ-like D5_N PF08706.11 ORY40559.1 - 2.4e-07 31.1 0.0 6.1e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 D5 N terminal like BRI3BP PF14965.6 ORY40559.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Negative regulator of p53/TP53 Ank_2 PF12796.7 ORY40635.1 - 2.4e-26 92.1 1.5 2.4e-16 60.1 0.3 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORY40635.1 - 2.1e-21 75.3 1.3 1.5e-05 25.2 0.0 4.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 ORY40635.1 - 1.1e-17 64.1 0.1 1.6e-06 28.5 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY40635.1 - 2.1e-14 52.2 0.0 0.049 14.2 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 ORY40635.1 - 3.5e-10 39.9 1.9 4.2e-05 23.7 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Imm_superinfect PF14373.6 ORY40635.1 - 0.015 15.2 0.1 3.6 7.6 0.0 2.7 3 0 0 3 3 3 0 Superinfection immunity protein DUF2384 PF09722.10 ORY40635.1 - 0.055 13.5 0.0 0.45 10.6 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2384) Ank PF00023.30 ORY40636.1 - 2.8e-29 100.3 3.8 2.6e-05 24.5 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.7 ORY40636.1 - 2.5e-27 95.3 1.0 2e-15 57.1 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY40636.1 - 2.6e-18 66.1 0.1 1.2e-05 25.7 0.0 3.3 1 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY40636.1 - 2.7e-18 64.2 0.5 0.08 13.5 0.0 5.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 ORY40636.1 - 8.2e-16 57.9 4.7 3.1e-05 24.2 0.1 3.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Imm_superinfect PF14373.6 ORY40636.1 - 0.0084 16.0 0.0 21 5.1 0.0 3.4 3 0 0 3 3 3 1 Superinfection immunity protein zf-ribbon_3 PF13248.6 ORY40636.1 - 0.57 9.7 5.5 13 5.4 0.2 3.0 3 0 0 3 3 3 0 zinc-ribbon domain MFS_1 PF07690.16 ORY40637.1 - 5.9e-44 150.4 39.3 5.9e-44 150.4 39.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY40637.1 - 3.2e-10 39.5 10.8 3.2e-10 39.5 10.8 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter GPR_Gpa2_C PF11970.8 ORY40637.1 - 0.47 10.6 5.6 3.9 7.6 1.1 3.7 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term zf-C2H2 PF00096.26 ORY40638.1 - 4.3e-07 30.0 10.3 0.00024 21.4 1.7 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 ORY40638.1 - 0.00032 21.3 4.5 0.00091 19.8 4.5 1.7 1 0 0 1 1 1 1 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 ORY40638.1 - 0.00055 20.2 7.3 0.015 15.7 2.3 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_8 PF15909.5 ORY40638.1 - 0.0015 18.8 0.5 0.0015 18.8 0.5 1.8 2 0 0 2 2 2 1 C2H2-type zinc ribbon zf-C2H2_4 PF13894.6 ORY40638.1 - 0.0084 16.9 12.8 0.046 14.6 2.2 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 ORY40638.1 - 0.0088 16.4 2.4 0.0088 16.4 2.4 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY40638.1 - 0.45 10.9 9.3 0.24 11.7 2.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Pkinase PF00069.25 ORY40640.1 - 3.9e-35 121.5 0.0 9e-35 120.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY40640.1 - 1.1e-27 97.0 0.0 4.4e-27 95.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Fascin PF06268.13 ORY40640.1 - 8.9e-09 35.6 0.1 0.00012 22.2 0.1 2.5 1 1 1 2 2 2 2 Fascin domain FGF PF00167.18 ORY40640.1 - 1.6e-05 25.0 0.2 5.6e-05 23.2 0.1 1.9 2 1 0 2 2 2 1 Fibroblast growth factor FRG1 PF06229.12 ORY40640.1 - 0.00061 19.6 0.0 0.083 12.6 0.0 2.2 1 1 1 2 2 2 2 FRG1-like domain APH PF01636.23 ORY40640.1 - 0.01 15.8 0.1 0.05 13.5 0.1 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 ORY40640.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY40640.1 - 0.05 12.9 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 ORY40641.1 - 1.5e-35 122.8 0.0 1.9e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY40641.1 - 6.9e-28 97.6 0.0 2e-27 96.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY40641.1 - 0.00059 19.8 0.1 0.001 19.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4287 PF14117.6 ORY40641.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4287) Sel1 PF08238.12 ORY40642.1 - 2.5e-223 717.4 129.0 5.9e-13 49.0 1.2 22.5 23 0 0 23 23 23 22 Sel1 repeat TPR_16 PF13432.6 ORY40642.1 - 3.6e-29 101.1 62.7 0.0065 17.1 0.9 15.8 1 1 16 19 19 19 15 Tetratricopeptide repeat TPR_19 PF14559.6 ORY40642.1 - 2.7e-14 53.4 71.9 0.22 12.0 0.3 19.7 19 2 2 21 21 21 2 Tetratricopeptide repeat Flu_M1_C PF08289.11 ORY40642.1 - 1.1e-13 51.2 0.4 30 4.9 0.0 11.6 3 2 12 15 15 15 0 Influenza Matrix protein (M1) C-terminal domain DIOX_N PF14226.6 ORY40642.1 - 5.1e-13 49.8 3.7 0.56 11.0 0.0 9.9 10 1 1 11 11 11 1 non-haem dioxygenase in morphine synthesis N-terminal TPR_6 PF13174.6 ORY40642.1 - 6.8e-13 48.3 33.5 1.7 9.5 0.1 17.6 20 2 0 20 20 19 4 Tetratricopeptide repeat TPR_12 PF13424.6 ORY40642.1 - 1.3e-10 41.4 72.2 0.15 12.4 1.9 19.7 5 1 14 19 19 19 9 Tetratricopeptide repeat MIT PF04212.18 ORY40642.1 - 3.9e-05 23.6 63.1 37 4.5 0.1 19.6 21 0 0 21 21 21 0 MIT (microtubule interacting and transport) domain TPR_17 PF13431.6 ORY40642.1 - 9.7e-05 22.5 54.7 34 5.1 0.2 16.5 16 1 0 16 16 16 0 Tetratricopeptide repeat AmpE PF17113.5 ORY40642.1 - 0.012 15.0 7.8 57 2.9 0.0 7.6 5 3 7 12 12 12 0 Regulatory signalling modulator protein AmpE TPR_3 PF07720.12 ORY40642.1 - 0.013 15.5 0.5 0.013 15.5 0.5 9.1 16 0 0 16 16 16 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY40642.1 - 0.03 14.4 56.7 1.7 8.9 0.3 15.8 18 0 0 18 18 16 0 Tetratricopeptide repeat Ssl1 PF04056.14 ORY40642.1 - 0.041 13.7 0.0 4.2e+02 0.6 0.0 5.6 4 3 3 9 9 9 0 Ssl1-like DNA_Packaging_2 PF11123.8 ORY40642.1 - 0.05 13.8 6.5 1.4 9.1 0.0 5.5 5 2 2 7 7 7 0 DNA packaging protein PurK_C PF17769.1 ORY40642.1 - 0.1 12.3 34.5 11 5.8 0.2 11.0 15 1 0 15 15 12 0 Phosphoribosylaminoimidazole carboxylase C-terminal domain Nucleopor_Nup85 PF07575.13 ORY40642.1 - 0.47 9.0 2.0 4.1 5.9 0.0 3.7 5 0 0 5 5 5 0 Nup85 Nucleoporin TPR_11 PF13414.6 ORY40642.1 - 3.5 7.4 140.0 0.39 10.4 2.5 22.3 23 1 0 23 23 23 0 TPR repeat DCX PF03607.17 ORY40644.1 - 2.5e-31 107.6 0.6 1.6e-13 50.5 0.0 3.3 3 0 0 3 3 3 3 Doublecortin KHA PF11834.8 ORY40644.1 - 0.084 13.0 0.0 21 5.3 0.0 2.5 2 0 0 2 2 2 0 KHA, dimerisation domain of potassium ion channel AMP-binding PF00501.28 ORY40645.1 - 4.7e-88 295.6 0.5 5.5e-88 295.4 0.5 1.0 1 0 0 1 1 1 1 AMP-binding enzyme CUE PF02845.16 ORY40647.1 - 1.1e-07 31.4 0.0 3.5e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 CUE domain HAP1_N PF04849.13 ORY40647.1 - 0.00012 21.4 1.6 0.00012 21.4 1.6 2.7 2 1 0 2 2 2 1 HAP1 N-terminal conserved region DUF2894 PF11445.8 ORY40647.1 - 0.11 12.9 12.7 1.9 8.9 7.8 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2894) DUF4407 PF14362.6 ORY40647.1 - 0.14 11.5 21.1 2.3 7.5 11.9 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Hydantoinase_B PF02538.14 ORY40647.1 - 0.15 10.4 1.0 0.24 9.8 1.0 1.3 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase PIN_8 PF18476.1 ORY40647.1 - 0.21 11.4 16.2 0.67 9.8 2.8 2.6 1 1 1 2 2 2 0 PIN like domain YlbD_coat PF14071.6 ORY40647.1 - 0.27 11.5 5.5 16 5.8 0.0 3.4 2 1 0 2 2 2 0 Putative coat protein Fib_alpha PF08702.10 ORY40647.1 - 0.4 10.9 14.1 0.82 9.8 7.9 3.2 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family SecD-TM1 PF13721.6 ORY40647.1 - 0.46 11.0 4.0 1.5 9.3 3.6 2.2 1 1 0 1 1 1 0 SecD export protein N-terminal TM region FlaC_arch PF05377.11 ORY40647.1 - 0.62 10.5 11.3 4.5 7.7 0.2 5.0 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) ATG16 PF08614.11 ORY40647.1 - 0.83 9.9 36.2 0.35 11.1 1.1 3.6 2 1 0 3 3 3 0 Autophagy protein 16 (ATG16) FAM194 PF14977.6 ORY40647.1 - 0.84 8.9 4.4 0.28 10.5 0.5 2.1 2 0 0 2 2 2 0 FAM194 protein FapA PF03961.13 ORY40647.1 - 1.2 7.7 11.2 3.3 6.2 4.6 2.4 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF4665 PF15679.5 ORY40647.1 - 2.8 8.6 7.6 15 6.3 0.9 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4665) Prominin PF05478.11 ORY40647.1 - 3.7 5.4 11.6 3.8 5.4 0.2 2.2 1 1 1 2 2 2 0 Prominin LPP PF04728.13 ORY40647.1 - 5.8 7.4 21.6 4.3 7.8 0.6 4.8 5 1 0 5 5 5 0 Lipoprotein leucine-zipper CFEM PF05730.11 ORY40648.1 - 0.47 10.6 7.7 0.92 9.7 7.7 1.6 1 1 0 1 1 1 0 CFEM domain LRR_4 PF12799.7 ORY40650.1 - 4.1e-16 58.8 52.3 0.00011 22.5 0.2 9.7 7 3 1 10 10 10 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORY40650.1 - 0.00029 20.4 11.2 0.44 10.0 0.3 4.5 1 1 3 4 4 4 3 Leucine-rich repeat LRR_8 PF13855.6 ORY40650.1 - 0.015 15.1 40.1 0.24 11.2 3.4 7.2 4 2 2 6 6 6 0 Leucine rich repeat LRR_6 PF13516.6 ORY40650.1 - 0.31 11.2 19.5 7 7.0 0.0 7.8 9 0 0 9 9 9 0 Leucine Rich repeat PAN_1 PF00024.26 ORY40651.1 - 8.8e-05 22.4 0.2 0.00017 21.5 0.2 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 ORY40651.1 - 0.08 12.9 1.7 0.12 12.3 0.9 1.7 2 0 0 2 2 2 0 PAN domain SAM_PNT PF02198.16 ORY40652.1 - 0.13 12.2 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain ABC_tran PF00005.27 ORY40654.1 - 3.9e-27 95.4 0.0 6.7e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 ORY40654.1 - 4.1e-05 23.6 0.1 8.1e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 ORY40654.1 - 0.00082 19.8 0.1 0.0037 17.7 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 ORY40654.1 - 0.0027 16.8 0.0 0.0047 16.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 ORY40654.1 - 0.0063 16.3 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY40654.1 - 0.0083 16.3 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY40654.1 - 0.012 15.9 0.1 0.041 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ORY40654.1 - 0.015 15.2 0.1 0.045 13.7 0.1 1.8 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 ORY40654.1 - 0.024 14.7 0.2 0.058 13.5 0.2 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.6 ORY40654.1 - 0.067 12.8 0.6 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 ORY40654.1 - 0.11 11.9 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_29 PF13555.6 ORY40654.1 - 0.11 12.2 0.2 0.11 12.2 0.2 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 ORY40654.1 - 0.11 12.1 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 ORY40654.1 - 0.13 12.3 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Dynamin family AAA_7 PF12775.7 ORY40654.1 - 0.13 11.8 0.2 0.24 10.9 0.2 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 ORY40654.1 - 0.18 12.2 0.0 0.59 10.6 0.0 1.8 2 0 0 2 2 2 0 RNA helicase AAA_21 PF13304.6 ORY40654.1 - 0.18 11.6 0.1 1.4 8.6 0.2 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RecA PF00154.21 ORY40654.1 - 0.18 11.2 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein MobB PF03205.14 ORY40654.1 - 0.19 11.6 0.1 0.47 10.4 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PelG PF16933.5 ORY40654.1 - 1.2 7.9 10.6 0.099 11.5 5.9 1.5 2 0 0 2 2 2 0 Putative exopolysaccharide Exporter (EPS-E) Ribonuclease_T2 PF00445.18 ORY40655.1 - 1.6e-09 38.2 0.1 2.2e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family 5_nucleotid_C PF02872.18 ORY40656.1 - 0.014 15.6 0.0 0.054 13.7 0.0 1.9 1 1 1 2 2 2 0 5'-nucleotidase, C-terminal domain UAA PF08449.11 ORY40657.1 - 1.5e-09 37.5 16.4 2e-09 37.1 16.4 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 ORY40657.1 - 1.2e-06 28.1 17.3 1.6e-06 27.7 17.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family E1-E2_ATPase PF00122.20 ORY40658.1 - 4.1e-29 101.4 1.4 1.1e-28 100.0 1.4 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 ORY40658.1 - 5.8e-10 39.8 0.1 0.0014 18.9 0.0 3.6 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 ORY40658.1 - 2.7e-07 30.7 0.0 8.2e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.26 ORY40658.1 - 7.9e-07 28.7 0.0 2.2e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus MBF1 PF08523.10 ORY40659.1 - 0.061 13.8 0.3 0.11 13.0 0.3 1.5 1 0 0 1 1 1 0 Multiprotein bridging factor 1 NDC10_II PF16787.5 ORY40661.1 - 4.1e-08 32.6 0.0 1.1e-07 31.3 0.0 1.6 1 1 1 2 2 2 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 Porin_O_P PF07396.11 ORY40661.1 - 0.0097 15.1 0.5 0.016 14.4 0.5 1.3 1 0 0 1 1 1 1 Phosphate-selective porin O and P AAA_lid_8 PF17868.1 ORY40663.1 - 0.012 15.5 0.4 2.6 8.0 0.0 2.7 2 0 0 2 2 2 0 AAA lid domain RSB_motif PF16294.5 ORY40663.1 - 0.15 12.3 2.4 0.81 10.0 0.6 2.5 2 0 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif TACC_C PF05010.14 ORY40665.1 - 4.3e-34 118.1 30.2 5.9e-34 117.6 30.2 1.1 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Filament PF00038.21 ORY40665.1 - 0.002 17.8 22.2 0.002 17.8 22.2 1.9 1 1 1 2 2 2 1 Intermediate filament protein UPF0061 PF02696.14 ORY40665.1 - 0.16 10.7 6.8 0.23 10.2 6.8 1.1 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family T6PP_N PF18572.1 ORY40665.1 - 0.94 9.3 6.3 0.19 11.5 1.3 2.3 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF3584 PF12128.8 ORY40665.1 - 3.5 5.0 28.5 4.9 4.5 28.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 ORY40665.1 - 6.7 6.0 23.3 11 5.3 22.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 ORY40665.1 - 8.7 5.1 34.0 12 4.7 22.1 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Jnk-SapK_ap_N PF09744.9 ORY40665.1 - 8.9 6.5 32.1 1.3 9.2 20.4 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 2OG-FeII_Oxy_3 PF13640.6 ORY40667.1 - 9.6e-11 42.4 0.1 3.9e-09 37.3 0.0 2.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DNA_pol_phi PF04931.13 ORY40667.1 - 0.002 16.3 20.4 0.0027 15.9 20.4 1.1 1 0 0 1 1 1 1 DNA polymerase phi SDA1 PF05285.12 ORY40667.1 - 0.11 11.9 18.3 0.16 11.4 18.3 1.2 1 0 0 1 1 1 0 SDA1 Slu7 PF11708.8 ORY40667.1 - 0.37 10.5 11.3 0.59 9.8 11.3 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Nop14 PF04147.12 ORY40667.1 - 0.66 8.1 18.2 0.84 7.8 18.2 1.1 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.10 ORY40667.1 - 1.1 9.6 10.5 1.6 9.0 10.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RRN3 PF05327.11 ORY40667.1 - 1.1 7.7 11.4 1.5 7.3 11.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 ORY40667.1 - 2 6.6 13.3 2.8 6.1 13.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Kdo PF06293.14 ORY40670.1 - 0.049 13.0 0.1 0.088 12.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C2H2_2 PF12756.7 ORY40671.1 - 3.7e-35 120.3 12.1 1.8e-29 102.0 0.2 3.2 2 1 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 ORY40671.1 - 2.4e-06 27.7 10.8 0.00025 21.3 6.8 3.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY40671.1 - 0.00026 21.3 6.4 0.00026 21.3 6.4 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type AKAP95 PF04988.12 ORY40671.1 - 2.8 8.2 6.4 18 5.5 2.9 2.6 2 1 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.6 ORY40671.1 - 4.3 8.4 17.7 0.5 11.3 1.5 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger PAH PF02671.21 ORY40672.1 - 2.1e-08 34.1 0.8 0.0063 16.6 0.0 2.4 2 0 0 2 2 2 2 Paired amphipathic helix repeat Pkinase PF00069.25 ORY40673.1 - 8.4e-21 74.5 0.0 1e-20 74.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY40673.1 - 2.5e-14 53.2 0.0 3.1e-14 52.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY40673.1 - 0.0096 15.9 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4291 PF14124.6 ORY40675.1 - 1.2e-56 191.5 0.0 1.9e-56 190.8 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4291) NMO PF03060.15 ORY40676.1 - 2.5e-61 207.9 2.2 3.3e-60 204.2 2.2 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ORY40676.1 - 2.4e-12 46.6 0.1 5.5e-10 38.8 0.1 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.17 ORY40676.1 - 0.0016 17.8 0.2 0.0033 16.8 0.2 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase His_biosynth PF00977.21 ORY40676.1 - 0.014 14.9 0.1 0.028 13.9 0.1 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein NanE PF04131.14 ORY40676.1 - 0.053 12.7 0.0 0.1 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.18 ORY40676.1 - 0.094 11.7 0.5 0.15 11.0 0.5 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Glu_synthase PF01645.17 ORY40676.1 - 0.11 11.6 1.6 0.29 10.2 1.4 1.9 1 1 0 1 1 1 0 Conserved region in glutamate synthase Ste5_C PF12194.8 ORY40684.1 - 0.01 15.8 0.6 0.16 11.9 0.6 2.2 1 1 0 1 1 1 0 Protein kinase Fus3-binding Glyco_transf_24 PF18404.1 ORY40687.1 - 1.3e-146 487.1 1.0 2e-146 486.4 1.0 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 ORY40687.1 - 4.9e-60 203.6 2.4 1.3e-55 189.1 0.0 3.4 3 0 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_15 PF18403.1 ORY40687.1 - 2.8e-41 141.8 0.6 3.1e-36 125.3 0.0 3.4 4 0 0 4 4 4 2 Thioredoxin-like domain UDP-g_GGTase PF06427.11 ORY40687.1 - 1.6e-37 128.0 0.0 3.1e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_13 PF18401.1 ORY40687.1 - 3.4e-35 120.9 6.7 1.1e-34 119.3 6.7 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 ORY40687.1 - 4.6e-35 121.2 2.1 9.2e-35 120.2 2.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 ORY40687.1 - 3.6e-06 26.7 0.0 8.8e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 8 ATP-sulfurylase PF01747.17 ORY40687.1 - 0.049 13.1 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 ATP-sulfurylase PrmA PF06325.13 ORY40689.1 - 3e-07 30.1 0.1 4.9e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ORY40689.1 - 8.9e-05 22.1 0.0 0.00025 20.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ORY40689.1 - 0.00021 22.0 0.0 0.0011 19.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ORY40689.1 - 0.00029 20.5 0.0 0.00042 20.0 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 CMAS PF02353.20 ORY40689.1 - 0.0051 16.1 0.0 0.012 14.9 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase PRMT5_C PF17286.2 ORY40689.1 - 0.017 15.0 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 PRMT5 oligomerisation domain Methyltransf_31 PF13847.6 ORY40689.1 - 0.022 14.6 0.0 0.08 12.7 0.0 1.9 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 ORY40689.1 - 0.023 14.5 0.0 0.051 13.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 ORY40689.1 - 0.027 14.5 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.11 ORY40689.1 - 0.032 13.2 0.0 0.063 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) PRMT5 PF05185.16 ORY40689.1 - 0.083 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.12 ORY40689.1 - 0.12 13.2 0.0 0.63 10.8 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Response_reg PF00072.24 ORY40692.1 - 4.6e-40 136.3 2.3 4.2e-19 68.8 0.6 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 ORY40692.1 - 1.9e-05 25.1 0.1 4.3e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1154 PF06631.11 ORY40693.1 - 0.76 9.8 3.9 1.6 8.8 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) Response_reg PF00072.24 ORY40694.1 - 4.3e-16 59.1 0.4 3.7e-10 40.0 0.1 2.3 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 ORY40694.1 - 0.048 14.2 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PRP38 PF03371.15 ORY40695.1 - 3.2e-27 95.5 0.3 5.6e-16 58.9 0.4 2.1 2 0 0 2 2 2 2 PRP38 family Pardaxin PF07425.11 ORY40695.1 - 0.32 10.6 0.6 0.85 9.3 0.0 1.9 2 0 0 2 2 2 0 Pardaxin Ras PF00071.22 ORY40696.1 - 1.9e-37 128.4 0.0 2.1e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY40696.1 - 4e-24 85.1 0.0 5.5e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY40696.1 - 2.3e-07 30.5 0.0 3.2e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORY40696.1 - 6.2e-05 22.5 0.0 0.00022 20.7 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 ORY40696.1 - 6.4e-05 23.4 0.0 8.7e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 ORY40696.1 - 0.0038 17.7 0.0 0.0067 16.8 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 ORY40696.1 - 0.015 15.2 0.1 0.6 10.0 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase Viral_helicase1 PF01443.18 ORY40696.1 - 0.017 14.9 0.1 0.022 14.5 0.1 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.9 ORY40696.1 - 0.021 14.6 0.0 0.18 11.5 0.0 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 ORY40696.1 - 0.025 14.8 0.1 0.042 14.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ORY40696.1 - 0.028 14.5 0.1 0.035 14.2 0.1 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase MeaB PF03308.16 ORY40696.1 - 0.043 12.8 0.0 3.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 ORY40696.1 - 0.05 13.9 0.0 0.089 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORY40696.1 - 0.061 13.0 0.0 3 7.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 ORY40696.1 - 0.087 12.4 0.0 0.57 9.7 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_5 PF07728.14 ORY40696.1 - 0.096 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.27 ORY40696.1 - 0.1 12.2 0.0 0.37 10.3 0.0 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 ORY40696.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY40696.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 ORY40696.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Chromo PF00385.24 ORY40697.1 - 2.4e-09 37.0 0.1 4.1e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain LepB_GAP_C PF18227.1 ORY40697.1 - 0.088 13.3 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 LepB GAP domain C-terminal subdomain Herpes_UL25 PF01499.16 ORY40698.1 - 0.14 10.6 2.7 0.23 9.9 2.7 1.3 1 0 0 1 1 1 0 Herpesvirus UL25 family PAN_4 PF14295.6 ORY40699.1 - 7.1e-14 51.5 6.8 0.00098 19.0 0.0 3.3 3 0 0 3 3 3 3 PAN domain PAN_1 PF00024.26 ORY40699.1 - 3.8e-11 42.8 4.0 0.0021 18.0 0.1 3.1 3 0 0 3 3 3 3 PAN domain MANEC PF07502.14 ORY40699.1 - 3e-05 24.2 4.5 1.7 9.0 0.1 3.1 3 0 0 3 3 3 3 MANEC domain PAN_3 PF08277.12 ORY40699.1 - 4.7e-05 23.1 9.8 0.0015 18.3 0.7 3.1 3 0 0 3 3 3 2 PAN-like domain Brix PF04427.18 ORY40700.1 - 4.2e-48 164.0 0.1 4.8e-48 163.8 0.1 1.0 1 0 0 1 1 1 1 Brix domain AAA_22 PF13401.6 ORY40701.1 - 4.2e-08 33.6 0.0 1.4e-07 31.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 ORY40701.1 - 4.3e-08 33.4 0.0 5.6e-07 29.7 0.0 2.6 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 ORY40701.1 - 5.5e-05 23.6 0.1 0.00039 20.8 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain Peptidase_M60 PF13402.6 ORY40701.1 - 0.0024 17.4 0.1 0.0039 16.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase M60, enhancin and enhancin-like NACHT PF05729.12 ORY40701.1 - 0.0098 15.8 0.1 2.9 7.8 0.0 2.8 2 1 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 ORY40701.1 - 0.015 15.6 0.1 1.2 9.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain DUF3384 PF11864.8 ORY40701.1 - 0.019 13.9 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) AAA PF00004.29 ORY40701.1 - 0.02 15.3 0.0 0.13 12.7 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ORY40701.1 - 0.022 14.9 0.0 0.067 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORY40701.1 - 0.025 15.1 0.4 0.14 12.7 0.0 2.6 3 1 0 3 3 3 0 AAA domain Adeno_IVa2 PF02456.15 ORY40701.1 - 0.03 13.1 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein ABC_tran PF00005.27 ORY40701.1 - 0.038 14.5 0.0 0.13 12.7 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.6 ORY40701.1 - 0.041 13.7 0.5 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY40701.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY40701.1 - 0.046 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase IstB_IS21 PF01695.17 ORY40701.1 - 0.063 13.0 0.0 7.6 6.2 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Consortin_C PF15281.6 ORY40701.1 - 0.075 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Consortin C-terminus AAA_25 PF13481.6 ORY40701.1 - 0.085 12.4 0.0 4.8 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 ORY40701.1 - 0.089 12.2 0.0 5.6 6.3 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 ORY40701.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA12 PF10443.9 ORY40701.1 - 0.47 9.1 3.6 2.2 6.9 0.0 2.6 3 0 0 3 3 3 0 RNA12 protein TPR_2 PF07719.17 ORY40703.1 - 8.3e-18 63.0 2.2 0.0012 18.8 0.0 7.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 ORY40703.1 - 4.4e-13 48.4 0.3 0.0023 17.7 0.0 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY40703.1 - 1.4e-12 47.9 16.2 0.049 14.1 0.1 6.5 5 1 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORY40703.1 - 5.6e-12 44.9 1.8 0.0042 17.2 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORY40703.1 - 2.7e-09 37.1 20.4 0.62 11.0 0.0 8.6 7 2 2 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY40703.1 - 3.7e-08 32.8 3.3 1.8 8.8 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY40703.1 - 4.3e-07 30.5 13.9 3.3 8.4 0.1 6.0 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 ORY40703.1 - 6e-06 26.3 4.0 0.00083 19.5 0.0 4.8 3 1 2 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY40703.1 - 1.3e-05 25.4 10.5 0.05 13.8 0.0 5.6 4 2 3 7 7 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 ORY40703.1 - 2.6e-05 24.4 17.8 1.2 9.5 0.1 6.1 6 1 0 6 6 6 2 Tetratricopeptide repeat BTAD PF03704.17 ORY40703.1 - 3.9e-05 24.1 8.8 0.033 14.6 1.9 2.9 2 1 0 2 2 2 2 Bacterial transcriptional activator domain TPR_17 PF13431.6 ORY40703.1 - 0.0013 19.0 0.0 7.4 7.2 0.0 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY40703.1 - 0.02 14.6 0.5 1.6 8.5 0.0 3.6 4 0 0 4 4 4 0 TPR repeat Fis1_TPR_C PF14853.6 ORY40703.1 - 0.029 14.4 2.6 60 3.8 0.0 4.7 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.6 ORY40703.1 - 0.034 14.8 14.8 0.18 12.5 0.1 6.2 7 0 0 7 7 5 0 Tetratricopeptide repeat Uteroglobin PF01099.17 ORY40703.1 - 0.11 12.8 0.2 0.54 10.6 0.0 2.1 2 0 0 2 2 2 0 Uteroglobin family TPR_10 PF13374.6 ORY40703.1 - 0.15 12.0 4.2 65 3.6 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Succ_DH_flav_C PF02910.20 ORY40703.1 - 0.24 11.4 1.4 13 5.8 0.1 2.4 2 0 0 2 2 2 0 Fumarate reductase flavoprotein C-term RPN7 PF10602.9 ORY40703.1 - 2 8.1 7.8 4.5 6.9 0.0 4.1 5 1 1 6 6 6 0 26S proteasome subunit RPN7 VWA_2 PF13519.6 ORY40703.1 - 4.8 7.9 6.5 36 5.1 0.2 3.5 3 1 1 4 4 3 0 von Willebrand factor type A domain LEH PF07858.12 ORY40704.1 - 0.013 15.5 0.1 0.027 14.6 0.1 1.6 1 1 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain DUF630 PF04783.12 ORY40705.1 - 0.014 15.5 0.0 0.042 14.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF630) PRKG1_interact PF15898.5 ORY40707.1 - 0.025 15.5 0.0 5.8 7.9 0.0 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF2563 PF10817.8 ORY40707.1 - 0.053 14.1 0.1 0.1 13.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2563) Cep57_CLD PF14073.6 ORY40708.1 - 2e-07 31.2 0.8 2e-07 31.2 0.8 3.6 4 0 0 4 4 4 1 Centrosome localisation domain of Cep57 DUF334 PF03904.13 ORY40708.1 - 0.22 11.0 0.3 0.53 9.8 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Tma16 PF11176.8 ORY40709.1 - 8.3e-42 142.5 0.1 1.1e-41 142.2 0.1 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 DUF3135 PF11333.8 ORY40709.1 - 0.083 13.2 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) PKcGMP_CC PF16808.5 ORY40709.1 - 0.12 12.2 1.8 0.21 11.5 0.3 2.1 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Phage_fiber_2 PF03406.13 ORY40709.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 Phage tail fibre repeat Pdase_C33_assoc PF14756.6 ORY40709.1 - 0.2 11.6 0.4 2.7 7.9 0.0 2.1 2 0 0 2 2 2 0 Peptidase_C33-associated domain Homeobox_KN PF05920.11 ORY40710.1 - 3.3e-16 58.9 0.1 5.9e-16 58.1 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 ORY40710.1 - 0.00014 21.6 0.1 0.00037 20.3 0.1 1.7 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 ORY40710.1 - 0.036 13.5 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Tubulin_C PF03953.17 ORY40712.1 - 2.7e-52 176.2 0.0 3.7e-52 175.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 ORY40713.1 - 7.9e-64 215.5 0.0 1e-63 215.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_3 PF14881.6 ORY40713.1 - 0.00039 20.1 0.0 0.00058 19.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin domain DUF3759 PF12585.8 ORY40714.1 - 9e-25 86.5 9.2 1.2e-24 86.2 9.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3759 PF12585.8 ORY40715.1 - 7.4e-14 51.6 0.1 8.1e-14 51.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Rep_1 PF01446.17 ORY40716.1 - 0.079 12.4 0.2 2.4 7.6 0.1 2.0 2 0 0 2 2 2 0 Replication protein Vps5 PF09325.10 ORY40716.1 - 0.084 12.4 5.0 2.7 7.5 2.2 2.8 1 1 1 2 2 2 0 Vps5 C terminal like MAGE PF01454.19 ORY40717.1 - 3.5e-32 111.8 4.3 1.6e-24 86.8 1.1 2.1 2 0 0 2 2 2 2 MAGE family SUIM_assoc PF16619.5 ORY40717.1 - 1.3 9.1 5.7 23 5.1 2.3 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Glycos_transf_2 PF00535.26 ORY40718.1 - 1.2e-29 103.3 0.1 2.9e-29 102.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 ORY40718.1 - 7.8e-18 64.9 1.0 1.4e-08 34.5 0.0 2.7 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 ORY40718.1 - 2.6e-08 34.1 0.0 6.5e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 ORY40718.1 - 0.00056 19.5 0.1 0.0013 18.3 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase CARDB PF07705.11 ORY40718.1 - 0.0095 16.2 1.9 0.031 14.6 1.9 1.9 1 0 0 1 1 1 1 CARDB Glycos_transf_1 PF00534.20 ORY40718.1 - 0.092 12.3 0.1 4.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferases group 1 EGF_Tenascin PF18720.1 ORY40719.1 - 0.00051 20.0 4.1 0.0014 18.6 4.1 1.7 1 0 0 1 1 1 1 Tenascin EGF domain EGF_2 PF07974.13 ORY40719.1 - 0.0019 18.5 2.9 0.0052 17.1 2.9 1.8 1 0 0 1 1 1 1 EGF-like domain zf-H2C2_2 PF13465.6 ORY40721.1 - 7.1e-07 29.4 0.7 7.1e-07 29.4 0.7 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY40721.1 - 8.4e-07 29.1 17.5 0.00038 20.7 0.3 4.1 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY40721.1 - 0.00019 22.0 6.5 0.0044 17.7 0.2 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY40721.1 - 0.00077 19.7 0.1 0.32 11.3 0.1 2.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY40721.1 - 0.0039 17.5 0.5 3.3 8.2 0.5 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY40721.1 - 0.69 10.0 12.6 0.29 11.2 0.5 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HE PF16278.5 ORY40721.1 - 3.6 8.1 8.7 0.61 10.6 0.3 2.9 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger DCP1 PF06058.13 ORY40722.1 - 6.5e-38 129.3 0.3 7.1e-38 129.1 0.3 1.0 1 0 0 1 1 1 1 Dcp1-like decapping family Ribosomal_L32e PF01655.18 ORY40723.1 - 8.7e-52 174.1 0.2 1.1e-51 173.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 Ribosomal_S9 PF00380.19 ORY40725.1 - 1.1e-19 71.1 0.0 1.3e-19 70.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 ILVD_EDD PF00920.21 ORY40726.1 - 2.2e-213 709.6 0.3 2.5e-213 709.4 0.3 1.0 1 0 0 1 1 1 1 Dehydratase family FeoA PF04023.14 ORY40726.1 - 0.15 12.3 0.1 1.2 9.5 0.0 2.6 2 0 0 2 2 2 0 FeoA domain Pkinase PF00069.25 ORY40727.1 - 3.2e-61 207.0 0.0 5.3e-60 203.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY40727.1 - 3.1e-28 98.8 0.0 3.2e-20 72.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY40727.1 - 1.7e-05 24.0 0.0 2.3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY40727.1 - 0.00013 21.5 0.1 0.0043 16.4 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY40727.1 - 0.00013 22.0 0.2 0.0016 18.4 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY40727.1 - 0.0033 16.8 0.1 0.012 14.9 0.0 1.9 2 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 ORY40727.1 - 0.0061 16.2 0.2 0.017 14.7 0.0 1.6 1 1 0 2 2 2 1 RIO1 family Seadorna_VP7 PF07387.11 ORY40727.1 - 0.033 13.3 0.0 0.06 12.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_C PF00433.24 ORY40727.1 - 0.11 13.2 1.1 0.27 12.0 1.1 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain FTA2 PF13095.6 ORY40727.1 - 0.14 11.8 0.1 4.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF1757 PF08560.10 ORY40731.1 - 0.026 14.6 0.0 0.65 10.1 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1757) Suf PF05843.14 ORY40731.1 - 0.28 11.1 2.7 0.35 10.8 2.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) NAM-associated PF14303.6 ORY40731.1 - 0.49 11.1 5.5 0.72 10.6 5.5 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF2109 PF09882.9 ORY40732.1 - 3.2 7.8 5.5 1.8 8.6 0.5 2.7 2 1 1 3 3 3 0 Predicted membrane protein (DUF2109) dCMP_cyt_deam_1 PF00383.23 ORY40733.1 - 6.3e-09 35.6 0.0 1.3e-08 34.7 0.0 1.5 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY40733.1 - 3e-05 23.8 0.2 0.0043 16.8 0.0 2.3 2 0 0 2 2 2 2 MafB19-like deaminase DUF5429 PF17494.2 ORY40733.1 - 0.09 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5429) Dynactin PF12455.8 ORY40734.1 - 0.018 14.3 6.4 0.039 13.2 1.1 2.8 2 0 0 2 2 2 0 Dynein associated protein Glu-tRNAGln PF02686.15 ORY40734.1 - 0.078 13.3 0.6 4.9 7.5 0.0 3.3 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit LMBR1 PF04791.16 ORY40735.1 - 3.4e-116 389.2 20.5 4e-116 388.9 20.5 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF2058 PF09831.9 ORY40736.1 - 0.78 9.9 4.8 5.1 7.2 1.3 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2058) DDHD PF02862.17 ORY40736.1 - 1.1 9.4 6.8 0.3 11.2 0.3 2.2 2 0 0 2 2 2 0 DDHD domain EPL1 PF10513.9 ORY40736.1 - 2.4 8.5 8.8 0.21 12.0 0.6 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like PC-Esterase PF13839.6 ORY40737.1 - 1.2e-06 28.6 0.6 0.0041 16.9 0.6 3.1 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Surp PF01805.20 ORY40739.1 - 1.5e-37 127.3 4.3 2.9e-19 68.8 0.2 2.4 2 0 0 2 2 2 2 Surp module PRP21_like_P PF12230.8 ORY40739.1 - 6.6e-32 111.1 8.1 4.7e-22 78.9 0.3 3.8 4 1 0 4 4 4 2 Pre-mRNA splicing factor PRP21 like protein zf_UBZ PF18439.1 ORY40739.1 - 0.00031 20.3 0.2 0.00067 19.2 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger ubiquitin PF00240.23 ORY40739.1 - 0.044 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin family zinc_ribbon_16 PF17034.5 ORY40739.1 - 0.22 11.7 0.4 2.5 8.3 0.1 2.3 2 0 0 2 2 2 0 Zinc-ribbon like family SRA1 PF07304.11 ORY40739.1 - 0.29 10.9 0.0 0.29 10.9 0.0 5.1 4 1 0 4 4 4 0 Steroid receptor RNA activator (SRA1) CTU2 PF10288.9 ORY40739.1 - 1.6 9.0 5.9 15 5.8 1.1 2.8 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Ndufs5 PF10200.9 ORY40740.1 - 0.0008 19.6 0.3 0.00089 19.5 0.3 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa UPF0203 PF05254.12 ORY40740.1 - 0.012 15.8 5.5 0.096 12.9 5.7 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) COX6B PF02297.17 ORY40740.1 - 0.13 12.5 6.6 1.6 9.0 6.6 1.9 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb CHCH PF06747.13 ORY40740.1 - 0.65 10.2 6.3 1.1 9.4 6.3 1.5 1 0 0 1 1 1 0 CHCH domain CAP_GLY PF01302.25 ORY40741.1 - 1.4e-23 82.7 0.3 2.1e-23 82.1 0.3 1.3 1 0 0 1 1 1 1 CAP-Gly domain EF-hand_7 PF13499.6 ORY40741.1 - 0.002 18.6 0.1 0.006 17.0 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 ORY40741.1 - 0.0061 16.4 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 ORY40741.1 - 0.041 13.4 0.5 0.16 11.6 0.0 2.2 2 0 0 2 2 2 0 EF hand Pkinase PF00069.25 ORY40742.1 - 4e-32 111.6 0.0 4.6e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY40742.1 - 7.1e-25 87.8 0.0 1.1e-24 87.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY40742.1 - 0.0016 18.4 0.1 0.0024 17.8 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family AAA_assoc_2 PF16193.5 ORY40742.1 - 0.19 12.1 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA C-terminal domain Ribosomal_L13e PF01294.18 ORY40743.1 - 7e-75 250.8 2.1 9.2e-75 250.4 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e Ada3 PF10198.9 ORY40744.1 - 0.099 12.8 0.0 0.099 12.8 0.0 1.1 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 TFIIA_gamma_N PF02268.16 ORY40744.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain WD40 PF00400.32 ORY40745.1 - 2.3e-31 107.3 18.7 1.6e-08 35.0 0.3 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY40745.1 - 7.5e-09 35.8 0.1 0.15 12.4 0.0 4.7 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY40745.1 - 4.9e-07 28.8 2.9 0.03 13.0 0.1 3.5 1 1 3 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.11 ORY40745.1 - 1.5e-06 28.3 0.1 0.0026 17.6 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY40745.1 - 9.6e-06 25.1 0.8 0.027 13.8 0.2 2.6 2 1 0 2 2 2 2 WD40-like domain Coatomer_WDAD PF04053.14 ORY40745.1 - 0.0022 17.1 0.0 0.1 11.6 0.0 2.4 1 1 1 2 2 2 1 Coatomer WD associated region Cytochrom_D1 PF02239.16 ORY40745.1 - 0.0024 16.5 0.2 0.49 8.9 0.1 2.4 2 1 1 3 3 3 2 Cytochrome D1 heme domain PQQ PF01011.21 ORY40745.1 - 0.0065 16.4 0.0 3.2 7.8 0.0 2.8 2 0 0 2 2 2 1 PQQ enzyme repeat DUF1764 PF08576.10 ORY40745.1 - 0.1 13.5 1.7 0.21 12.5 1.7 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) TRP_2 PF08344.11 ORY40745.1 - 0.13 12.5 0.0 0.34 11.1 0.0 1.7 1 0 0 1 1 1 0 Transient receptor ion channel II LRR_6 PF13516.6 ORY40746.1 - 4e-14 51.4 26.6 0.15 12.2 0.0 10.2 10 0 0 10 10 10 4 Leucine Rich repeat TIR_2 PF13676.6 ORY40746.1 - 3.5e-08 34.1 0.0 1e-07 32.6 0.0 1.8 1 0 0 1 1 1 1 TIR domain FAM76 PF16046.5 ORY40746.1 - 0.0082 15.5 1.4 0.013 14.9 1.4 1.2 1 0 0 1 1 1 1 FAM76 protein LRR_8 PF13855.6 ORY40746.1 - 0.044 13.5 4.6 12 5.7 0.1 4.9 3 2 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 ORY40746.1 - 0.083 13.4 22.3 0.56 10.7 0.1 6.8 6 2 2 8 8 8 0 Leucine Rich repeats (2 copies) BBP1_C PF15272.6 ORY40746.1 - 0.11 12.3 3.3 0.25 11.2 3.3 1.5 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal LRR_1 PF00560.33 ORY40746.1 - 0.59 10.9 7.7 33 5.6 0.0 5.4 5 0 0 5 5 5 0 Leucine Rich Repeat Amnionless PF14828.6 ORY40747.1 - 0.26 10.1 0.4 0.33 9.7 0.4 1.1 1 0 0 1 1 1 0 Amnionless zf-C2H2 PF00096.26 ORY40749.1 - 0.0011 19.3 4.1 0.0023 18.3 4.1 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY40749.1 - 0.024 15.5 1.7 0.046 14.6 1.7 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORY40749.1 - 0.028 14.6 0.4 0.04 14.1 0.4 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger zf-RAG1 PF10426.9 ORY40749.1 - 0.11 12.6 0.4 0.19 11.9 0.4 1.4 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain zf-C2H2 PF00096.26 ORY40750.1 - 0.00057 20.2 2.7 0.0013 19.1 2.7 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY40750.1 - 0.011 16.5 0.6 0.03 15.1 0.6 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger PHD PF00628.29 ORY40755.1 - 0.0011 18.8 1.6 0.0011 18.8 1.6 1.9 2 0 0 2 2 2 1 PHD-finger Anp1 PF03452.14 ORY40756.1 - 0.11 11.9 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Anp1 GTF2I PF02946.14 ORY40757.1 - 0.093 12.8 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 GTF2I-like repeat GAGA_bind PF06217.12 ORY40758.1 - 0.073 13.4 5.9 0.082 13.2 5.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family KDZ PF18758.1 ORY40759.1 - 4.8e-12 46.0 0.0 1.4e-11 44.4 0.0 1.7 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase SpoVAD PF07451.11 ORY40759.1 - 0.085 11.5 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) zf-C2H2 PF00096.26 ORY40760.1 - 0.00091 19.6 4.1 0.0019 18.5 4.1 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY40760.1 - 0.021 15.6 1.7 0.038 14.8 1.7 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORY40760.1 - 0.024 14.8 0.4 0.033 14.3 0.4 1.2 1 0 0 1 1 1 0 Aberrant zinc-finger zf-RAG1 PF10426.9 ORY40760.1 - 0.091 12.9 0.4 0.16 12.1 0.4 1.4 1 0 0 1 1 1 0 Recombination-activating protein 1 zinc-finger domain zf-C2H2 PF00096.26 ORY40761.1 - 0.00059 20.2 2.7 0.0013 19.1 2.7 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY40761.1 - 0.011 16.5 0.6 0.031 15.1 0.6 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Frag1 PF10277.9 ORY40763.1 - 0.023 14.2 1.6 0.028 13.9 1.6 1.1 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family Ricin_B_lectin PF00652.22 ORY40764.1 - 2e-14 53.9 10.3 3.4e-08 33.8 0.1 3.1 3 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain Mucin PF01456.17 ORY40764.1 - 3.2e-05 24.0 26.0 3.2e-05 24.0 26.0 4.3 2 1 2 4 4 4 1 Mucin-like glycoprotein PAN_1 PF00024.26 ORY40765.1 - 2.3e-21 75.5 29.5 1.5e-06 28.1 0.2 5.6 5 1 0 5 5 5 4 PAN domain PAN_4 PF14295.6 ORY40765.1 - 7.8e-17 60.9 18.1 0.00013 21.8 0.9 4.4 4 0 0 4 4 4 4 PAN domain Ricin_B_lectin PF00652.22 ORY40765.1 - 9.7e-07 29.1 1.9 1.1e-05 25.7 1.6 2.5 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain PAN_2 PF08276.11 ORY40765.1 - 1.6e-05 24.9 20.8 0.029 14.5 0.6 5.0 4 0 0 4 4 4 3 PAN-like domain Mucin PF01456.17 ORY40765.1 - 0.00058 19.9 39.8 0.00058 19.9 39.8 3.4 3 0 0 3 3 3 1 Mucin-like glycoprotein PAN_3 PF08277.12 ORY40765.1 - 0.001 18.8 6.0 0.0071 16.1 0.4 5.3 6 0 0 6 6 6 4 PAN-like domain Fer4_19 PF06902.11 ORY40765.1 - 0.47 10.6 2.5 4.7 7.4 0.1 2.8 2 0 0 2 2 2 0 Divergent 4Fe-4S mono-cluster SAM_Ste50p PF09235.10 ORY40765.1 - 1.8 8.8 7.0 11 6.4 0.2 3.2 3 0 0 3 3 3 0 Ste50p, sterile alpha motif AJAP1_PANP_C PF15298.6 ORY40765.1 - 6.6 6.9 46.3 0.68 10.1 11.7 3.0 3 0 0 3 3 3 0 AJAP1/PANP C-terminus Abhydrolase_1 PF00561.20 ORY40766.1 - 5.1e-17 62.4 0.1 5.1e-13 49.3 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY40766.1 - 1.6e-14 55.0 0.3 2e-14 54.7 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY40766.1 - 6.2e-11 42.0 0.0 1.1e-10 41.2 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 ORY40766.1 - 5.7e-05 22.8 0.3 0.00013 21.7 0.3 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 ORY40766.1 - 0.006 16.1 0.0 0.042 13.3 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 ORY40766.1 - 0.027 14.3 0.1 0.11 12.3 0.1 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 ORY40766.1 - 0.033 13.8 0.0 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF2048 PF09752.9 ORY40766.1 - 0.089 11.9 0.2 0.12 11.5 0.2 1.3 1 0 0 1 1 1 0 Abhydrolase domain containing 18 LRR_4 PF12799.7 ORY40767.1 - 4e-15 55.7 38.1 0.00082 19.7 2.4 8.7 6 3 4 10 10 10 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORY40767.1 - 0.37 10.3 22.9 0.18 11.3 0.9 4.3 1 1 3 4 4 4 0 Leucine-rich repeat LRR_6 PF13516.6 ORY40767.1 - 6.6 7.1 25.4 2.2 8.6 0.0 7.7 9 0 0 9 9 9 0 Leucine Rich repeat FlbD PF06289.11 ORY40768.1 - 1.7 8.3 4.2 0.6 9.8 0.1 2.2 3 0 0 3 3 3 0 Flagellar and Swarming motility proteins DUF3421 PF11901.8 ORY40770.1 - 1.8e-20 73.0 1.2 7e-08 32.5 0.2 3.3 2 1 1 3 3 3 3 Protein of unknown function (DUF3421) LRR_4 PF12799.7 ORY40771.1 - 4.7e-17 61.8 26.7 0.0019 18.6 0.9 9.3 4 2 7 12 12 12 10 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY40771.1 - 0.0019 18.1 1.4 5 7.4 0.0 6.0 6 0 0 6 6 6 1 Leucine Rich repeat Recep_L_domain PF01030.24 ORY40771.1 - 0.051 13.7 9.2 0.19 11.9 0.1 4.3 1 1 4 5 5 5 0 Receptor L domain LRR_8 PF13855.6 ORY40771.1 - 7.3 6.4 20.2 3.6 7.4 2.5 5.5 4 1 2 6 6 6 0 Leucine rich repeat Abhydrolase_1 PF00561.20 ORY40772.1 - 1.1e-17 64.5 0.1 8.9e-10 38.6 0.1 3.3 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY40772.1 - 1.2e-13 52.1 0.0 2e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY40772.1 - 3.3e-12 46.2 0.0 4.8e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 ORY40772.1 - 0.0042 16.8 0.0 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) LRR_9 PF14580.6 ORY40772.1 - 0.0053 16.3 3.5 0.0053 16.3 3.5 2.8 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 ORY40772.1 - 0.0082 16.5 35.1 0.35 11.4 1.6 7.1 3 2 1 6 6 6 3 Leucine Rich repeats (2 copies) Peptidase_S9 PF00326.21 ORY40772.1 - 0.017 14.6 0.3 0.064 12.7 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 ORY40772.1 - 0.027 14.3 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase LIP PF03583.14 ORY40772.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Secretory lipase DLH PF01738.18 ORY40772.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Palm_thioest PF02089.15 ORY40772.1 - 0.18 11.6 0.0 0.43 10.4 0.0 1.5 1 1 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 ORY40773.1 - 2.8e-19 69.8 0.1 1.7e-17 63.9 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY40773.1 - 4.9e-14 53.5 0.6 5.9e-14 53.2 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY40773.1 - 7.5e-09 35.2 0.0 1.6e-08 34.2 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_2 PF01674.18 ORY40773.1 - 0.081 12.4 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 2) PGAP1 PF07819.13 ORY40773.1 - 0.15 11.7 0.3 0.66 9.7 0.2 1.9 2 0 0 2 2 2 0 PGAP1-like protein UPF0227 PF05728.12 ORY40773.1 - 0.2 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Spo7 PF03907.13 ORY40774.1 - 3.3e-13 49.6 4.0 5.4e-13 48.9 3.7 1.5 1 1 0 1 1 1 1 Spo7-like protein Tmemb_18A PF09771.9 ORY40774.1 - 3.2e-06 27.5 0.1 4.1e-06 27.2 0.1 1.1 1 0 0 1 1 1 1 Transmembrane protein 188 Otopetrin PF03189.13 ORY40774.1 - 0.0025 16.7 0.1 0.0028 16.6 0.1 1.1 1 0 0 1 1 1 1 Otopetrin Ni_hydr_CYTB PF01292.20 ORY40774.1 - 0.0074 15.9 0.0 0.0095 15.6 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 DUF4271 PF14093.6 ORY40774.1 - 0.0079 16.1 2.5 0.011 15.6 2.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) Lectin_N PF03954.14 ORY40774.1 - 0.046 13.5 0.2 0.099 12.4 0.2 1.6 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF4064 PF13273.6 ORY40774.1 - 0.067 13.5 3.2 0.1 12.9 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) PsbT PF01405.17 ORY40774.1 - 0.097 12.5 1.0 0.22 11.4 1.0 1.7 1 0 0 1 1 1 0 Photosystem II reaction centre T protein DUF5305 PF17231.2 ORY40774.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) SpoIIIAH PF12685.7 ORY40774.1 - 0.28 11.0 0.3 0.47 10.3 0.3 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein SH3_1 PF00018.28 ORY40775.1 - 0.0022 17.6 0.1 0.059 13.0 0.0 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 ORY40775.1 - 0.011 15.6 0.1 0.32 10.9 0.1 2.4 1 1 0 1 1 1 0 Variant SH3 domain VSP PF03302.13 ORY40775.1 - 0.07 12.0 0.0 0.095 11.5 0.0 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein FecCD PF01032.18 ORY40775.1 - 0.1 11.6 1.1 0.13 11.2 1.1 1.1 1 0 0 1 1 1 0 FecCD transport family KGK PF08872.10 ORY40775.1 - 0.2 12.2 0.0 0.3 11.6 0.0 1.3 1 0 0 1 1 1 0 KGK domain KH_1 PF00013.29 ORY40778.1 - 5.9e-28 96.5 0.0 7.9e-08 32.0 0.0 6.0 6 0 0 6 6 6 5 KH domain SAM_1 PF00536.30 ORY40778.1 - 4e-11 43.2 0.0 1e-10 41.9 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 ORY40778.1 - 1.2e-07 31.8 1.9 5.6e-07 29.6 0.0 3.0 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) RabGAP-TBC PF00566.18 ORY40779.1 - 1e-24 87.4 0.0 1.3e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain zf-MYND PF01753.18 ORY40780.1 - 3.3e-09 36.7 10.6 7.3e-09 35.6 10.6 1.6 1 0 0 1 1 1 1 MYND finger Arm_3 PF16186.5 ORY40780.1 - 0.026 14.1 0.1 0.089 12.4 0.1 1.8 2 0 0 2 2 2 0 Atypical Arm repeat Ribosomal_S4 PF00163.19 ORY40780.1 - 0.07 14.0 0.1 0.31 12.0 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S4/S9 N-terminal domain Chromo_shadow PF01393.19 ORY40781.1 - 0.023 14.8 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Chromo shadow domain Chromo PF00385.24 ORY40781.1 - 0.046 13.6 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.6 ORY40782.1 - 0.00034 21.2 0.0 0.00084 19.9 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 ORY40782.1 - 0.00064 20.2 0.0 0.0014 19.1 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1667 PF07892.11 ORY40782.1 - 0.096 12.8 0.2 0.32 11.1 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) HrpB7 PF09486.10 ORY40783.1 - 0.00072 20.0 7.3 0.022 15.1 0.8 2.4 2 0 0 2 2 2 2 Bacterial type III secretion protein (HrpB7) CENP-Q PF13094.6 ORY40783.1 - 0.00094 19.4 2.5 0.00094 19.4 2.5 3.1 1 1 2 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit MbeD_MobD PF04899.12 ORY40783.1 - 0.065 13.4 0.1 0.21 11.7 0.1 1.8 1 1 0 1 1 1 0 MbeD/MobD like ADIP PF11559.8 ORY40783.1 - 0.12 12.5 17.6 0.16 12.1 7.0 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding KELK PF15796.5 ORY40783.1 - 0.29 11.6 11.8 0.036 14.5 5.6 2.4 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF16 PF01519.16 ORY40783.1 - 0.56 10.7 17.9 0.46 11.0 7.1 2.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 ORF6N PF10543.9 ORY40783.1 - 0.6 10.4 2.4 1.3 9.3 2.0 1.9 1 1 0 1 1 1 0 ORF6N domain Fib_alpha PF08702.10 ORY40783.1 - 1.1 9.5 12.2 0.8 9.9 4.8 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Macoilin PF09726.9 ORY40783.1 - 2 6.9 12.2 2.8 6.4 12.2 1.1 1 0 0 1 1 1 0 Macoilin family Cep57_CLD_2 PF14197.6 ORY40783.1 - 3 8.0 10.0 3 8.0 0.4 3.2 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Fez1 PF06818.15 ORY40783.1 - 3.5 8.0 16.8 27 5.1 6.9 2.1 1 1 1 2 2 2 0 Fez1 Csm1_N PF18504.1 ORY40783.1 - 4 7.8 13.3 5.2 7.5 0.5 3.4 2 1 1 3 3 3 0 Csm1 N-terminal domain Exonuc_VII_L PF02601.15 ORY40783.1 - 5 6.6 10.3 12 5.4 9.8 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit Seryl_tRNA_N PF02403.22 ORY40783.1 - 5.6 7.2 16.4 17 5.7 9.9 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Phage_GP20 PF06810.11 ORY40783.1 - 5.6 6.7 21.9 0.19 11.5 8.3 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 Tropomyosin_1 PF12718.7 ORY40783.1 - 8.8 6.5 23.8 14 5.8 14.0 2.7 1 1 1 2 2 2 0 Tropomyosin like CENP-K PF11802.8 ORY40783.1 - 9.4 5.7 15.3 47 3.4 14.1 1.9 1 1 0 1 1 1 0 Centromere-associated protein K zf-MYND PF01753.18 ORY40785.1 - 3.3e-07 30.3 15.8 8.1e-07 29.0 15.8 1.7 1 0 0 1 1 1 1 MYND finger DUF5578 PF17741.1 ORY40785.1 - 0.079 12.4 0.4 7.8 5.8 0.0 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5578) Peptidase_M16_C PF05193.21 ORY40785.1 - 0.093 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase M16 inactive domain Cas_Cas02710 PF09670.10 ORY40785.1 - 0.15 10.8 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) zf-MYND PF01753.18 ORY40786.1 - 2e-08 34.2 11.1 4e-08 33.2 11.1 1.5 1 0 0 1 1 1 1 MYND finger DUF2828 PF11443.8 ORY40786.1 - 0.027 12.6 0.0 0.041 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) zf-Mss51 PF13824.6 ORY40786.1 - 0.14 12.2 3.4 0.37 10.9 3.4 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-tcix PF14952.6 ORY40786.1 - 0.22 11.2 3.1 0.44 10.2 3.1 1.5 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding zf-HIT PF04438.16 ORY40786.1 - 0.86 9.5 6.8 2.3 8.2 6.8 1.6 1 0 0 1 1 1 0 HIT zinc finger 3HCDH_N PF02737.18 ORY40787.1 - 4.7e-53 179.7 0.5 8.8e-53 178.9 0.5 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 ORY40787.1 - 2.6e-32 111.3 0.1 5.7e-32 110.2 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain UDPG_MGDP_dh_N PF03721.14 ORY40787.1 - 0.091 12.3 0.6 0.24 11.0 0.6 1.7 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Sacchrp_dh_NADP PF03435.18 ORY40787.1 - 0.14 12.4 0.6 0.26 11.5 0.6 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF4744 PF15918.5 ORY40788.1 - 4 8.4 5.9 13 6.7 5.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) Response_reg PF00072.24 ORY40789.1 - 8.4e-08 32.4 0.1 1.7e-06 28.2 0.1 2.6 1 1 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 ORY40789.1 - 3.1e-05 24.5 0.0 6.8e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 ORY40789.1 - 0.0015 18.5 0.0 0.012 15.7 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_9 PF13426.7 ORY40789.1 - 0.0049 17.1 0.0 0.036 14.3 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 ORY40789.1 - 0.021 14.8 0.0 0.089 12.8 0.0 2.1 2 0 0 2 2 2 0 PAS fold PAS_4 PF08448.10 ORY40789.1 - 0.034 14.4 0.0 0.74 10.1 0.0 2.6 2 0 0 2 2 2 0 PAS fold Response_reg PF00072.24 ORY40790.1 - 1.5e-23 83.1 0.2 5.3e-23 81.3 0.2 2.0 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 ORY40790.1 - 6.3e-18 65.3 0.1 1.4e-17 64.2 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 ORY40790.1 - 0.002 18.1 0.3 0.0089 16.0 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Tho2 PF11262.8 ORY40790.1 - 0.0039 16.4 1.9 0.0072 15.6 1.9 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 HATPase_c_3 PF13589.6 ORY40790.1 - 0.0085 15.9 0.0 0.054 13.3 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rab_bind PF16704.5 ORY40790.1 - 0.018 15.1 1.0 0.06 13.4 1.0 1.9 1 0 0 1 1 1 0 Rab binding domain Nup54_57_C PF18570.1 ORY40790.1 - 0.02 14.5 0.6 0.048 13.2 0.6 1.6 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain RRM_1 PF00076.22 ORY40790.1 - 0.031 14.1 0.0 0.085 12.7 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1664 PF07889.12 ORY40790.1 - 0.055 13.5 3.2 0.054 13.5 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) HATPase_c_2 PF13581.6 ORY40790.1 - 0.1 12.6 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Spc7 PF08317.11 ORY40790.1 - 0.17 10.7 9.9 0.29 10.0 9.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 ORY40790.1 - 0.2 11.0 4.0 0.32 10.3 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 ORY40790.1 - 0.21 12.1 6.7 0.48 10.9 6.7 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Golgin_A5 PF09787.9 ORY40790.1 - 0.22 10.9 8.7 0.46 9.9 8.7 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF5082 PF16888.5 ORY40790.1 - 0.36 11.1 5.4 0.94 9.8 5.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DUF4201 PF13870.6 ORY40790.1 - 0.69 9.6 11.4 1.9 8.2 11.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Syntaxin-6_N PF09177.11 ORY40790.1 - 1.5 9.4 4.2 4.9 7.8 4.2 1.9 1 0 0 1 1 1 0 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.12 ORY40790.1 - 5.6 7.0 12.2 0.85 9.7 4.4 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.6 ORY40790.1 - 7.3 7.0 10.8 17 5.8 10.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Cep57_CLD_2 PF14197.6 ORY40790.1 - 9.7 6.4 7.7 10 6.3 2.9 2.7 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Response_reg PF00072.24 ORY40791.1 - 5.2e-25 87.8 0.5 5.3e-24 84.5 0.3 2.7 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 ORY40791.1 - 9.1e-21 74.5 0.1 2.9e-20 72.9 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_8 PF13188.7 ORY40791.1 - 8.2e-06 25.7 0.0 0.00092 19.2 0.0 2.8 2 0 0 2 2 2 1 PAS domain HisKA PF00512.25 ORY40791.1 - 0.00026 21.0 0.0 0.0017 18.3 0.0 2.4 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 ORY40791.1 - 0.0024 18.1 0.0 0.015 15.6 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 ORY40791.1 - 0.008 16.2 0.0 0.038 14.0 0.0 2.2 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 ORY40791.1 - 0.0092 15.8 0.1 0.03 14.1 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Imm8 PF15586.6 ORY40791.1 - 0.012 15.7 0.1 0.09 12.8 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 8 PAS_4 PF08448.10 ORY40791.1 - 0.012 15.8 0.0 0.027 14.7 0.0 1.7 1 0 0 1 1 1 0 PAS fold PAS_3 PF08447.12 ORY40791.1 - 0.044 14.1 0.0 0.17 12.2 0.0 2.1 1 0 0 1 1 1 0 PAS fold Cyclin_N PF00134.23 ORY40793.1 - 8.6e-13 48.1 1.3 1.4e-12 47.5 0.4 1.8 2 1 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 ORY40793.1 - 1.7e-06 28.0 0.2 0.00012 22.0 0.2 2.3 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.19 ORY40793.1 - 0.0071 16.4 0.2 0.054 13.6 0.0 2.2 2 1 0 2 2 2 1 Cyclin, C-terminal domain DUF1254 PF06863.12 ORY40794.1 - 1e-29 103.3 2.2 1.8e-29 102.5 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1254) DUF1214 PF06742.11 ORY40794.1 - 3.3e-26 91.9 0.2 2e-25 89.4 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1214) DUF1254 PF06863.12 ORY40795.1 - 2.7e-29 101.9 1.1 4.8e-29 101.1 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1254) DUF1214 PF06742.11 ORY40795.1 - 4e-25 88.4 0.7 1.3e-24 86.7 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1214) Aminotran_3 PF00202.21 ORY40796.1 - 4.5e-120 401.0 0.0 5.3e-120 400.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ORY40796.1 - 0.19 10.8 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DUF4918 PF16265.5 ORY40796.1 - 0.21 11.0 0.0 0.36 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4918) DOT1 PF08123.13 ORY40797.1 - 6.4e-53 179.3 0.0 9.8e-53 178.7 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_23 PF13489.6 ORY40797.1 - 0.0042 17.0 0.1 0.0084 16.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY40797.1 - 0.0048 16.7 0.0 0.0096 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY40797.1 - 0.0051 17.5 0.0 0.011 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY40797.1 - 0.092 13.5 0.1 0.25 12.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain NDUFA12 PF05071.16 ORY40798.1 - 2.1e-30 105.4 3.8 2.3e-30 105.3 3.8 1.0 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 2-oxogl_dehyd_N PF16078.5 ORY40798.1 - 0.017 14.7 2.1 0.028 14.0 2.1 1.4 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus Ras PF00071.22 ORY40799.1 - 5.9e-57 191.8 0.1 7.1e-57 191.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY40799.1 - 5.1e-33 113.8 0.1 8.4e-33 113.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY40799.1 - 1.3e-12 47.6 0.0 1.5e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY40799.1 - 1.7e-07 31.3 0.0 2.8e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY40799.1 - 1.6e-05 24.5 0.1 0.0003 20.4 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORY40799.1 - 2.4e-05 23.8 0.0 3.2e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 ORY40799.1 - 8e-05 22.6 0.1 0.0049 16.8 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase SRPRB PF09439.10 ORY40799.1 - 0.00028 20.4 0.0 0.0004 19.9 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 ORY40799.1 - 0.00053 19.8 0.7 0.018 14.8 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.18 ORY40799.1 - 0.001 18.4 0.1 0.04 13.2 0.1 2.2 2 0 0 2 2 2 1 Septin DLIC PF05783.11 ORY40799.1 - 0.0013 17.6 0.0 0.97 8.2 0.0 2.1 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) PduV-EutP PF10662.9 ORY40799.1 - 0.002 17.9 0.0 0.062 13.0 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 ORY40799.1 - 0.0031 17.1 0.1 0.022 14.4 0.0 2.1 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 ORY40799.1 - 0.0071 16.6 0.0 0.013 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY40799.1 - 0.016 15.3 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY40799.1 - 0.019 14.7 0.2 0.026 14.2 0.2 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY40799.1 - 0.019 15.3 0.1 0.024 15.0 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 ORY40799.1 - 0.026 14.1 0.1 0.038 13.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 ORY40799.1 - 0.052 13.4 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 ORY40799.1 - 0.052 13.5 0.0 0.11 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TniB PF05621.11 ORY40799.1 - 0.082 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 ORY40799.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Beta_helix_2 PF18835.1 ORY40799.1 - 0.12 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Beta helix repeat of Inulin fructotransferase RNA_helicase PF00910.22 ORY40799.1 - 0.13 12.7 0.1 0.27 11.6 0.0 1.6 2 0 0 2 2 1 0 RNA helicase AAA_18 PF13238.6 ORY40799.1 - 0.18 12.4 0.1 0.24 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ORY40799.1 - 0.19 12.3 0.2 0.25 11.9 0.2 1.6 1 1 0 1 1 1 0 ABC transporter Ribosomal_L4 PF00573.22 ORY40800.1 - 1.3e-39 135.9 0.3 1.8e-39 135.4 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family FHA PF00498.26 ORY40802.1 - 3.7e-19 68.8 0.1 6.8e-19 68.0 0.1 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 ORY40802.1 - 9.3e-07 29.1 0.0 6.8e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Presenilin PF01080.17 ORY40802.1 - 0.18 10.6 1.8 0.13 11.0 1.8 1.1 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 ORY40802.1 - 0.77 8.0 4.3 0.87 7.9 4.3 1.1 1 0 0 1 1 1 0 Menin NPR3 PF03666.13 ORY40802.1 - 7.5 5.2 7.9 8.2 5.1 7.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ank_2 PF12796.7 ORY40805.1 - 5e-42 142.4 8.2 3.5e-13 50.0 0.0 5.4 2 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 ORY40805.1 - 1.2e-30 104.6 18.2 1.8e-07 31.3 0.1 8.6 9 0 0 9 9 8 6 Ankyrin repeat Ank_4 PF13637.6 ORY40805.1 - 1.4e-29 102.1 12.3 4.4e-09 36.7 0.1 8.0 4 2 4 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY40805.1 - 5.7e-27 93.4 7.6 3.5e-07 30.4 0.0 8.1 4 2 5 9 9 9 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY40805.1 - 5.7e-21 72.4 16.7 2.2e-05 24.5 0.0 10.2 11 0 0 11 11 10 4 Ankyrin repeat HlyU PF10115.9 ORY40805.1 - 0.0017 18.4 0.0 0.0043 17.1 0.0 1.6 1 0 0 1 1 1 1 Transcriptional activator HlyU Asp_protease_2 PF13650.6 ORY40805.1 - 0.0049 17.5 0.4 38 5.0 0.0 3.8 3 0 0 3 3 3 0 Aspartyl protease gag-asp_proteas PF13975.6 ORY40805.1 - 0.12 12.9 0.5 34 5.1 0.0 3.6 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease PKcGMP_CC PF16808.5 ORY40805.1 - 0.14 12.1 0.1 0.14 12.1 0.1 2.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc29 PF17082.5 ORY40805.1 - 1.5 8.6 11.7 0.11 12.3 5.9 2.1 2 1 0 2 2 2 0 Spindle Pole Component 29 Fez1 PF06818.15 ORY40805.1 - 2.6 8.4 22.5 0.12 12.9 6.9 3.2 2 1 0 3 3 3 0 Fez1 DUF641 PF04859.12 ORY40805.1 - 3.7 7.9 17.6 0.078 13.3 3.0 3.6 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) CHDCT2 PF08074.11 ORY40805.1 - 5.3 7.2 6.9 3.3 7.8 3.9 2.3 3 0 0 3 3 1 0 CHDCT2 (NUC038) domain HAUS-augmin3 PF14932.6 ORY40805.1 - 8.1 5.9 20.7 6 6.4 4.9 3.3 3 0 0 3 3 3 0 HAUS augmin-like complex subunit 3 SlyX PF04102.12 ORY40805.1 - 8.8 7.0 13.8 1.9 9.1 0.8 4.0 3 1 1 4 4 4 0 SlyX Ank_2 PF12796.7 ORY40806.1 - 3.7e-20 72.3 2.5 1.4e-13 51.3 0.3 3.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORY40806.1 - 1e-16 60.5 3.0 7.2e-07 29.4 0.0 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 ORY40806.1 - 5.6e-15 55.5 2.6 2.2e-08 34.5 0.1 4.8 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY40806.1 - 2.3e-13 49.0 0.0 7.5e-05 22.8 0.0 5.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 ORY40806.1 - 1.6e-10 41.0 2.2 1.3e-06 28.6 0.4 3.7 1 1 4 5 5 5 3 Ankyrin repeats (many copies) Rop-like PF05082.13 ORY40806.1 - 0.0069 16.2 1.0 0.0069 16.2 1.0 4.9 6 0 0 6 6 6 1 Rop-like FSIP1 PF15554.6 ORY40807.1 - 2.2e-09 36.9 3.9 9.6e-06 24.9 0.0 3.3 2 1 0 3 3 3 2 FSIP1 family Mog1 PF04603.12 ORY40807.1 - 0.59 10.5 3.1 0.25 11.7 0.4 1.8 2 0 0 2 2 2 0 Ran-interacting Mog1 protein Pkinase_Tyr PF07714.17 ORY40808.1 - 5.9e-32 111.0 0.0 9.4e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORY40808.1 - 9.1e-30 103.9 0.0 1.7e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 ORY40808.1 - 6.5e-13 48.2 13.7 3.8e-06 26.6 0.1 3.7 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 ORY40808.1 - 3.7e-11 43.1 10.2 0.0067 16.8 1.1 4.2 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY40808.1 - 5.9e-08 32.2 4.0 1.2 9.9 0.0 5.5 5 0 0 5 5 5 3 Leucine Rich Repeat Kinase-like PF14531.6 ORY40808.1 - 0.00051 19.5 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 ORY40809.1 - 5.6e-31 107.8 0.0 8.5e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORY40809.1 - 8.9e-26 90.8 0.0 2.1e-25 89.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 ORY40809.1 - 0.00084 18.7 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like LRR_4 PF12799.7 ORY40809.1 - 0.0019 18.6 8.0 1.7 9.2 0.6 3.7 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY40809.1 - 0.01 15.6 8.5 0.057 13.2 6.0 2.8 2 1 1 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 ORY40809.1 - 0.032 14.8 3.6 5.4 8.0 0.3 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat Pkinase_Tyr PF07714.17 ORY40810.1 - 2.7e-24 85.8 0.0 6.4e-23 81.4 0.0 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 ORY40810.1 - 1.2e-21 77.3 0.0 2.2e-19 69.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 ORY40810.1 - 0.0035 16.7 0.0 0.005 16.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like LRR_8 PF13855.6 ORY40811.1 - 0.00054 19.7 3.8 0.0062 16.3 1.5 1.8 1 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 ORY40811.1 - 0.035 14.5 2.6 0.15 12.5 0.8 2.2 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY40811.1 - 0.27 11.9 4.9 18 6.3 0.2 3.1 3 0 0 3 3 3 0 Leucine Rich Repeat Pox_A3L PF05288.11 ORY40812.1 - 0.086 12.8 0.1 0.17 11.9 0.1 1.5 1 1 0 1 1 1 0 Poxvirus A3L Protein GREB1 PF15782.5 ORY40813.1 - 9.7 3.2 18.8 12 2.9 18.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer zf-CCCH PF00642.24 ORY40814.1 - 3.5e-06 26.8 10.7 0.00095 19.0 0.9 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 ORY40814.1 - 0.0013 18.5 15.0 0.042 13.7 3.1 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 ORY40814.1 - 0.0065 17.1 5.1 1.1 10.0 0.5 2.8 1 1 1 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 ORY40814.1 - 0.0085 16.1 20.3 0.21 11.7 5.7 2.4 2 0 0 2 2 2 2 Zinc finger domain Helitron_like_N PF14214.6 ORY40820.1 - 3.3e-16 60.1 0.0 4.1e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus DUF4368 PF14287.6 ORY40820.1 - 0.0074 16.6 0.1 0.019 15.2 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4368) PIF1 PF05970.14 ORY40822.1 - 2.5e-08 33.5 0.0 2.7e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 ORY40822.1 - 1.2e-07 31.7 0.0 1.2e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY40822.1 - 1.8e-06 28.3 0.2 2.6e-06 27.9 0.2 1.3 1 1 0 1 1 1 1 AAA domain MeaB PF03308.16 ORY40822.1 - 6.2e-06 25.4 0.0 6.9e-06 25.2 0.0 1.0 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP_bind_1 PF03029.17 ORY40822.1 - 0.00024 21.0 0.0 0.0003 20.6 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 ORY40822.1 - 0.00058 19.5 0.1 0.0012 18.6 0.0 1.5 1 1 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY40822.1 - 0.0016 18.9 0.0 0.0017 18.8 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain DUF463 PF04317.12 ORY40822.1 - 0.0071 15.3 0.1 0.0081 15.1 0.1 1.1 1 0 0 1 1 1 1 YcjX-like family, DUF463 ResIII PF04851.15 ORY40822.1 - 0.0075 16.3 0.0 0.0089 16.0 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 ORY40822.1 - 0.0088 15.1 0.0 0.0093 15.1 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 ORY40822.1 - 0.012 14.9 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.18 ORY40822.1 - 0.018 14.8 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase APS_kinase PF01583.20 ORY40822.1 - 0.02 14.8 0.0 0.026 14.4 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.6 ORY40822.1 - 0.042 14.1 0.0 0.053 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ORY40822.1 - 0.057 13.3 0.0 0.075 12.9 0.0 1.2 1 0 0 1 1 1 0 NTPase SRP54 PF00448.22 ORY40822.1 - 0.066 12.8 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_18 PF13238.6 ORY40822.1 - 0.066 13.8 0.1 0.12 12.9 0.1 1.5 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 ORY40822.1 - 0.068 12.7 0.1 0.12 11.8 0.1 1.4 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 ORY40822.1 - 0.07 12.9 0.0 0.074 12.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY40822.1 - 0.094 13.1 0.1 0.16 12.4 0.0 1.4 2 0 0 2 2 1 0 RNA helicase DUF2075 PF09848.9 ORY40822.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.19 ORY40822.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 ORY40822.1 - 0.11 11.6 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit AAA_24 PF13479.6 ORY40822.1 - 0.15 11.8 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 ORY40822.1 - 0.15 10.9 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain IIGP PF05049.13 ORY40822.1 - 0.16 11.0 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) UvrD-helicase PF00580.21 ORY40822.1 - 0.17 11.3 0.0 0.22 11.0 0.0 1.1 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Herpes_Helicase PF02689.14 ORY40822.1 - 0.19 9.6 0.0 0.19 9.6 0.0 1.0 1 0 0 1 1 1 0 Helicase Thymidylate_kin PF02223.17 ORY40822.1 - 0.19 11.4 0.1 0.24 11.1 0.1 1.2 1 0 0 1 1 1 0 Thymidylate kinase PIF1 PF05970.14 ORY40823.1 - 1.5e-05 24.3 0.0 0.0011 18.2 0.0 2.1 1 1 0 1 1 1 1 PIF1-like helicase DUF4797 PF16051.5 ORY40824.1 - 0.028 14.4 0.3 0.054 13.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4797) Mannosyl_trans3 PF11051.8 ORY40825.1 - 1.2e-42 146.2 0.0 2e-42 145.5 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 ORY40825.1 - 0.026 14.5 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Peptidase_S9 PF00326.21 ORY40828.1 - 4.5e-43 147.2 0.0 6.7e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ORY40828.1 - 4.9e-06 26.4 0.3 0.052 13.2 0.0 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY40828.1 - 1.2e-05 24.7 0.1 0.0012 18.2 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PD40 PF07676.12 ORY40828.1 - 1.5e-05 24.8 1.7 0.017 15.0 0.1 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DLH PF01738.18 ORY40828.1 - 1.9e-05 24.4 0.1 4.6e-05 23.1 0.1 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.12 ORY40828.1 - 8.5e-05 21.4 0.0 0.00029 19.6 0.0 1.8 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 ORY40828.1 - 0.00023 20.9 0.0 0.58 9.7 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 ORY40828.1 - 0.0087 15.9 0.1 0.1 12.5 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 ORY40828.1 - 0.023 14.6 0.0 0.16 11.8 0.0 2.0 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.10 ORY40828.1 - 0.038 14.1 0.0 0.08 13.1 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Esterase PF00756.20 ORY40828.1 - 0.047 13.3 0.0 0.096 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative esterase DUF829 PF05705.14 ORY40828.1 - 0.095 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) FSH1 PF03959.13 ORY40828.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PQQ_3 PF13570.6 ORY40828.1 - 0.11 13.0 1.7 9.5 6.9 0.1 3.2 2 0 0 2 2 2 0 PQQ-like domain Esterase_phd PF10503.9 ORY40828.1 - 0.16 11.4 0.6 2.1 7.8 0.3 2.5 2 1 0 2 2 2 0 Esterase PHB depolymerase Thiamine_BP PF01910.17 ORY40830.1 - 7.5e-06 25.8 0.0 2.2e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 Thiamine-binding protein Thiamine_BP PF01910.17 ORY40831.1 - 5e-11 42.4 0.1 5.8e-11 42.2 0.1 1.1 1 0 0 1 1 1 1 Thiamine-binding protein Glyco_tran_28_C PF04101.16 ORY40832.1 - 1.3e-24 87.0 0.0 2e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain ASCH PF04266.14 ORY40832.1 - 0.0012 19.4 0.0 0.002 18.7 0.0 1.3 1 0 0 1 1 1 1 ASCH domain Col_cuticle_N PF01484.17 ORY40834.1 - 0.025 14.6 0.2 0.031 14.3 0.2 1.1 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Thiamine_BP PF01910.17 ORY40835.1 - 3.4e-10 39.7 0.0 3.9e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Thiamine-binding protein Lactamase_B_2 PF12706.7 ORY40836.1 - 2.7e-10 40.1 0.0 5.7e-05 22.7 0.0 2.9 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY40836.1 - 3.3e-09 37.1 0.2 1.1e-08 35.3 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.6 ORY40836.1 - 0.0025 17.5 0.0 0.37 10.5 0.0 2.4 2 0 0 2 2 2 2 tRNase Z endonuclease adh_short PF00106.25 ORY40838.1 - 2.7e-33 115.1 0.0 1.9e-28 99.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY40838.1 - 2.8e-20 72.9 0.0 2.5e-19 69.8 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY40838.1 - 7.3e-12 45.5 0.0 1.2e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY40838.1 - 0.00012 21.7 0.1 0.00039 20.0 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 ORY40838.1 - 0.0031 16.9 0.3 0.0049 16.2 0.3 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YjeF_N PF03853.15 ORY40838.1 - 0.016 15.1 0.2 0.033 14.1 0.2 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus DUF3889 PF13028.6 ORY40838.1 - 0.027 14.4 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) RmlD_sub_bind PF04321.17 ORY40838.1 - 0.094 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 ORY40839.1 - 1.7e-06 27.6 0.0 0.0026 17.3 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY40839.1 - 0.0055 16.3 0.0 0.01 15.4 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HoxA13_N PF12284.8 ORY40839.1 - 0.11 13.1 0.0 0.15 12.7 0.0 1.3 1 0 0 1 1 1 0 Hox protein A13 N terminal adh_short PF00106.25 ORY40840.1 - 4.5e-17 62.2 0.2 1.1e-16 60.8 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY40840.1 - 2.2e-09 37.3 0.0 3.7e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY40840.1 - 2.6e-08 34.0 0.1 4.1e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY40840.1 - 0.022 14.2 0.1 0.029 13.8 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family YjeF_N PF03853.15 ORY40840.1 - 0.088 12.7 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus RmlD_sub_bind PF04321.17 ORY40840.1 - 0.1 11.7 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DUF1647 PF07801.11 ORY40840.1 - 0.1 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1647) DUF3889 PF13028.6 ORY40840.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) Homeodomain PF00046.29 ORY40841.1 - 2.3e-11 43.4 0.3 3.6e-11 42.7 0.3 1.3 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 ORY40841.1 - 0.0049 16.6 0.1 0.0088 15.8 0.1 1.3 1 0 0 1 1 1 1 Homeodomain-like domain Homeobox_KN PF05920.11 ORY40841.1 - 0.015 15.2 1.0 0.03 14.2 0.1 2.0 2 0 0 2 2 2 0 Homeobox KN domain DUF2285 PF10074.9 ORY40841.1 - 0.041 14.5 0.1 0.07 13.8 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2285) IF2_N PF04760.15 ORY40841.1 - 0.089 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region MarR_2 PF12802.7 ORY40841.1 - 0.16 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 MarR family MerR_1 PF13411.6 ORY40841.1 - 0.17 12.0 0.1 0.45 10.6 0.0 1.7 2 0 0 2 2 2 0 MerR HTH family regulatory protein Homeodomain PF00046.29 ORY40842.1 - 3.6e-05 23.5 0.0 7.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Homeodomain IF2_N PF04760.15 ORY40842.1 - 0.14 12.0 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Sigma70_r3 PF04539.16 ORY40842.1 - 0.15 12.1 0.0 0.44 10.7 0.0 1.9 1 0 0 1 1 1 0 Sigma-70 region 3 Sulfate_transp PF00916.20 ORY40905.1 - 7.6e-39 133.5 26.6 1.1e-38 133.0 26.6 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORY40905.1 - 7.2e-09 35.3 0.0 1.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain FAD_binding_3 PF01494.19 ORY40909.1 - 4.9e-28 98.4 0.1 5.9e-27 94.8 0.1 2.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY40909.1 - 8.8e-13 48.1 1.4 2.4e-06 27.0 0.1 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY40909.1 - 5.5e-09 36.1 0.5 0.0013 18.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY40909.1 - 2.1e-08 33.3 2.9 1.3e-05 24.1 0.2 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.6 ORY40909.1 - 7.9e-07 29.2 0.1 4.3e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORY40909.1 - 3e-06 26.7 2.6 0.0071 15.6 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY40909.1 - 2.2e-05 23.7 1.2 0.0081 15.3 0.0 2.3 2 1 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.24 ORY40909.1 - 2.9e-05 23.3 0.3 8.7e-05 21.8 0.4 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 ORY40909.1 - 4.6e-05 23.9 1.9 0.14 12.8 0.1 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY40909.1 - 4.9e-05 22.6 3.2 0.00017 20.8 3.2 1.9 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 ORY40909.1 - 0.0002 21.4 0.1 0.89 9.5 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding SE PF08491.10 ORY40909.1 - 0.00021 20.4 0.0 0.067 12.2 0.0 2.4 3 0 0 3 3 3 2 Squalene epoxidase Trp_halogenase PF04820.14 ORY40909.1 - 0.0013 17.7 1.7 0.4 9.5 0.3 2.3 2 0 0 2 2 2 2 Tryptophan halogenase 3HCDH_N PF02737.18 ORY40909.1 - 0.0021 18.0 0.0 0.015 15.2 0.1 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 ORY40909.1 - 0.012 15.2 0.1 0.034 13.8 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 ORY40909.1 - 0.026 13.9 0.3 0.026 13.9 0.3 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ORY40909.1 - 0.048 12.9 0.2 0.31 10.3 0.1 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.24 ORY40909.1 - 0.06 12.6 0.3 1 8.6 0.3 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Rap_GAP PF02145.15 ORY40910.1 - 6.1e-59 198.7 0.0 8e-59 198.3 0.0 1.1 1 0 0 1 1 1 1 Rap/ran-GAP WD40 PF00400.32 ORY40911.1 - 8.9e-14 51.7 9.8 0.22 12.4 0.0 7.0 6 1 1 7 7 7 5 WD domain, G-beta repeat zf-H2C2_2 PF13465.6 ORY40912.1 - 1.5e-31 107.4 54.3 1e-05 25.7 1.0 9.2 9 0 0 9 9 9 8 Zinc-finger double domain zf-C2H2 PF00096.26 ORY40912.1 - 9e-30 101.5 61.5 6.7e-05 23.1 2.4 9.2 9 0 0 9 9 9 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY40912.1 - 3.8e-20 70.8 60.0 0.0027 18.4 1.6 9.2 9 0 0 9 9 9 7 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORY40912.1 - 6.7e-05 22.6 0.2 6.7e-05 22.6 0.2 6.2 7 0 0 7 7 7 2 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 ORY40912.1 - 7.1e-05 23.0 19.1 0.052 13.8 0.3 6.0 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY40912.1 - 0.00048 20.4 31.0 0.27 11.7 0.0 7.6 8 0 0 8 8 8 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY40912.1 - 0.0024 17.8 0.0 0.0024 17.8 0.0 7.0 7 0 0 7 7 7 2 C2H2-type zinc finger GAGA PF09237.11 ORY40912.1 - 0.0058 16.4 11.9 0.56 10.1 0.2 4.5 4 0 0 4 4 4 2 GAGA factor zf-C2HE PF16278.5 ORY40912.1 - 0.013 16.0 34.3 0.27 11.7 0.2 6.7 3 3 3 6 6 6 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_3rep PF18868.1 ORY40912.1 - 0.1 13.3 14.1 11 6.7 0.4 5.9 2 1 2 5 5 5 0 Zinc finger C2H2-type, 3 repeats BolA PF01722.18 ORY40912.1 - 0.14 12.4 3.8 2.1 8.7 0.0 3.5 4 0 0 4 4 4 0 BolA-like protein zf-RING_11 PF17123.5 ORY40912.1 - 1 9.2 5.0 26 4.7 1.6 3.4 3 0 0 3 3 3 0 RING-like zinc finger zf-Sec23_Sec24 PF04810.15 ORY40912.1 - 1.1 9.4 4.4 2.7 8.1 0.1 3.6 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Glyco_hydro_15 PF00723.21 ORY40913.1 - 3.1e-42 144.9 1.6 1.6e-41 142.5 1.6 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 Glyco_hydro_15 PF00723.21 ORY40914.1 - 2.3e-41 142.0 0.8 1.2e-40 139.7 0.8 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 DUF4512 PF14975.6 ORY40915.1 - 0.091 13.5 5.1 2.3 9.1 0.7 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4512) adh_short PF00106.25 ORY40916.1 - 9.3e-34 116.6 0.1 1.6e-31 109.3 0.1 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY40916.1 - 3.5e-23 82.4 0.0 2.6e-18 66.5 0.1 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY40916.1 - 1.6e-07 31.4 0.0 2.9e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY40916.1 - 4.5e-05 23.0 0.7 0.00015 21.3 0.7 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY40916.1 - 0.00089 18.7 0.1 0.002 17.6 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Pkinase PF00069.25 ORY40917.1 - 8.8e-53 179.3 0.0 2.2e-52 178.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY40917.1 - 4.5e-30 104.8 0.0 2.1e-29 102.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY40917.1 - 0.0096 15.3 0.1 0.029 13.7 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY40917.1 - 0.01 14.6 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase ATP-synt_G PF04718.15 ORY40919.1 - 4.3e-17 62.8 0.2 5e-17 62.6 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit DTW PF03942.15 ORY40920.1 - 7.3e-18 65.0 0.0 1.3e-17 64.2 0.0 1.4 1 1 0 1 1 1 1 DTW domain W2 PF02020.18 ORY40922.1 - 7.2e-23 80.5 2.0 4.7e-22 77.9 2.0 2.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 ORY40922.1 - 8.9e-11 41.1 16.1 0.00012 21.6 3.7 3.4 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 ORY40922.1 - 7.9e-10 38.7 0.0 2e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 ORY40922.1 - 5.7e-05 23.5 0.1 0.0001 22.7 0.1 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 ORY40922.1 - 0.00012 21.8 5.0 0.00012 21.8 5.0 2.9 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 ORY40922.1 - 0.00082 18.4 0.3 0.0015 17.6 0.3 1.4 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 ORY40922.1 - 0.0037 15.5 0.7 0.007 14.6 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NAD_binding_8 PF13450.6 ORY40923.1 - 4.4e-10 39.7 0.1 7.6e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ORY40923.1 - 1.5e-09 37.7 0.0 1.6e-09 37.6 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 ORY40923.1 - 5.1e-05 23.0 1.2 9.4e-05 22.1 1.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ORY40923.1 - 0.05 12.7 0.3 0.068 12.2 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 ORY40923.1 - 0.093 11.9 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY40923.1 - 0.11 11.6 0.2 0.16 11.0 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 ORY40924.1 - 2.1e-19 70.2 0.0 2.4e-19 69.9 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DUF563 PF04577.14 ORY40925.1 - 4.9e-27 95.4 0.3 2e-25 90.2 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF563) TPR_14 PF13428.6 ORY40925.1 - 3.7e-05 24.2 0.0 0.64 11.0 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY40925.1 - 0.00048 20.0 0.1 0.062 13.4 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY40925.1 - 0.0048 17.1 0.3 2.2 8.6 0.0 2.8 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 ORY40925.1 - 0.054 14.0 0.0 7.9 7.1 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY40925.1 - 0.15 12.8 0.2 1.1e+02 3.8 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Fungal_trans PF04082.18 ORY40926.1 - 0.0031 16.6 0.2 0.0062 15.6 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain LURAP PF14854.6 ORY40926.1 - 0.02 14.8 0.0 0.24 11.4 0.0 2.2 2 0 0 2 2 2 0 Leucine rich adaptor protein Zn_clus PF00172.18 ORY40926.1 - 0.029 14.5 7.2 0.057 13.5 7.2 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 ORY40927.1 - 7e-29 99.0 35.4 6.5e-09 35.8 1.3 6.2 6 0 0 6 6 6 6 Zinc-finger double domain zf-C2H2 PF00096.26 ORY40927.1 - 1e-25 88.7 30.6 0.00022 21.5 0.1 6.2 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 ORY40927.1 - 2.2e-16 59.6 14.8 0.016 15.5 0.0 6.5 6 1 0 6 6 6 6 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 ORY40927.1 - 5.8e-16 57.8 32.2 0.0054 17.5 0.7 6.2 6 0 0 6 6 6 6 C2H2-type zinc finger zf-met PF12874.7 ORY40927.1 - 2.4e-08 34.1 19.6 2.6 8.5 0.1 6.3 6 0 0 6 6 6 4 Zinc-finger of C2H2 type DUF3268 PF11672.8 ORY40927.1 - 0.017 15.4 4.0 0.3 11.4 0.2 2.5 2 1 0 2 2 2 0 zinc-finger-containing domain zf-LYAR PF08790.11 ORY40927.1 - 0.025 14.5 3.4 2.1 8.3 0.0 3.7 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger C1_4 PF07975.12 ORY40927.1 - 0.045 14.0 14.1 0.07 13.4 1.0 3.6 2 1 0 3 3 3 0 TFIIH C1-like domain zf-C2H2_6 PF13912.6 ORY40927.1 - 0.061 13.4 23.2 0.49 10.5 0.1 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger C1_1 PF00130.22 ORY40927.1 - 0.087 12.7 17.6 0.77 9.7 2.7 4.7 3 2 2 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C4 PF00105.18 ORY40927.1 - 1.9 9.0 9.5 23 5.5 0.8 4.1 1 1 3 4 4 4 0 Zinc finger, C4 type (two domains) zf-H2C2_5 PF13909.6 ORY40927.1 - 2.5 7.9 27.7 3.3 7.6 0.1 5.8 6 1 0 6 6 6 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 ORY40927.1 - 3.2 8.1 21.8 8 6.9 0.1 5.1 1 1 2 4 4 4 0 C2H2 type zinc-finger (2 copies) CLASP_N PF12348.8 ORY40928.1 - 3.8e-09 36.4 1.3 1.2e-08 34.8 0.1 2.3 2 1 0 2 2 2 1 CLASP N terminal CRAL_TRIO PF00650.20 ORY40930.1 - 4.2e-27 94.8 0.0 5.9e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORY40930.1 - 1.7e-07 31.3 0.0 3.3e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ORY40930.1 - 0.048 13.8 0.0 0.07 13.3 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 ORY40931.1 - 3.1e-27 95.3 0.0 4.6e-27 94.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORY40931.1 - 6.7e-08 32.6 0.4 1.2e-07 31.8 0.4 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ORY40931.1 - 0.00043 20.4 0.0 0.00065 19.9 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain LRR_8 PF13855.6 ORY40932.1 - 5.5e-15 54.9 14.0 2.1e-07 30.6 3.1 3.6 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY40932.1 - 6.1e-05 23.3 16.0 0.083 13.3 0.1 4.4 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY40932.1 - 0.00017 21.7 18.0 2.2 9.1 0.2 7.5 6 1 2 8 8 8 2 Leucine Rich Repeat F-box-like PF12937.7 ORY40932.1 - 0.11 12.4 0.1 0.31 11.0 0.1 1.8 1 0 0 1 1 1 0 F-box-like LRR_9 PF14580.6 ORY40932.1 - 0.12 11.8 1.1 10 5.6 0.6 2.1 1 1 1 2 2 2 0 Leucine-rich repeat Cornifin PF02389.15 ORY40933.1 - 2e-05 24.8 0.0 0.098 12.9 0.0 2.4 1 1 1 2 2 2 2 Cornifin (SPRR) family DUF3809 PF12723.7 ORY40933.1 - 0.038 14.3 8.3 54 4.1 0.0 6.2 1 1 8 9 9 9 0 Protein of unknown function (DUF3809) LRR_8 PF13855.6 ORY40934.1 - 9.6e-12 44.5 26.1 1.3e-05 24.8 1.0 3.7 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY40934.1 - 6.9e-06 26.3 21.4 3.2e-05 24.2 1.6 4.3 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY40934.1 - 0.0051 16.8 10.4 3.6 7.9 0.0 4.2 4 0 0 4 4 4 3 Leucine Rich repeat FNIP PF05725.12 ORY40934.1 - 0.01 16.0 2.4 6.6 7.0 0.0 4.4 2 1 2 4 4 4 0 FNIP Repeat LRR_1 PF00560.33 ORY40934.1 - 2.3 9.1 30.1 5.9 7.9 0.4 7.6 7 2 0 7 7 7 0 Leucine Rich Repeat Epimerase PF01370.21 ORY40935.1 - 3.4e-33 115.1 0.0 4.4e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY40935.1 - 1.3e-32 112.9 0.0 1.7e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORY40935.1 - 7.2e-19 68.0 0.0 2.2e-18 66.4 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 ORY40935.1 - 1.4e-18 67.4 0.0 7.6e-17 61.7 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ORY40935.1 - 3.8e-17 62.8 0.0 2e-16 60.4 0.1 1.8 1 1 1 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 ORY40935.1 - 1e-12 48.1 0.1 6.8e-11 42.2 0.1 2.5 3 0 0 3 3 3 1 NmrA-like family Polysacc_synt_2 PF02719.15 ORY40935.1 - 1.5e-09 37.4 0.0 2.4e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 ORY40935.1 - 3.3e-06 26.4 0.0 4.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 ORY40935.1 - 0.00011 22.2 0.3 0.00027 20.9 0.3 1.6 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 ORY40935.1 - 0.085 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_2 PF03446.15 ORY40935.1 - 0.19 11.9 0.0 0.45 10.7 0.0 1.5 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF848 PF05852.11 ORY40936.1 - 0.032 14.3 11.8 0.94 9.6 3.6 2.6 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Seryl_tRNA_N PF02403.22 ORY40936.1 - 0.043 14.0 8.1 0.19 12.0 0.8 2.7 2 1 1 3 3 2 0 Seryl-tRNA synthetase N-terminal domain DUF1843 PF08898.10 ORY40936.1 - 0.14 12.7 0.1 0.47 11.0 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) DivIC PF04977.15 ORY40936.1 - 0.42 10.4 9.5 0.34 10.7 0.5 3.4 1 1 3 4 4 4 0 Septum formation initiator Cnn_1N PF07989.11 ORY40936.1 - 1.2 9.3 14.4 13 6.0 4.5 3.9 1 1 3 4 4 4 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 ORY40936.1 - 1.4 9.4 14.8 4.8 7.7 1.6 3.4 2 2 1 3 3 3 0 Cell division protein ZapB DUF4201 PF13870.6 ORY40936.1 - 1.5 8.5 16.6 0.038 13.7 3.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) bZIP_1 PF00170.21 ORY40936.1 - 1.6 8.9 11.2 19 5.5 0.6 4.1 2 2 2 4 4 4 0 bZIP transcription factor GAS PF13851.6 ORY40936.1 - 1.6 8.0 20.1 0.077 12.3 7.7 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding SKA2 PF16740.5 ORY40936.1 - 1.7 8.4 13.7 2 8.3 2.2 3.0 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 APG6_N PF17675.1 ORY40936.1 - 2.4 8.7 20.6 4.5 7.8 7.7 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region ArAE_2_N PF10337.9 ORY40936.1 - 3.2 6.7 4.2 5.2 6.0 4.2 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal DUF4795 PF16043.5 ORY40936.1 - 3.5 7.2 13.7 2.7 7.5 5.8 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) JIP_LZII PF16471.5 ORY40936.1 - 3.9 7.7 17.5 4.6 7.5 1.2 3.7 3 1 1 4 4 4 0 JNK-interacting protein leucine zipper II DUF948 PF06103.11 ORY40936.1 - 4.5 7.6 10.2 25 5.2 0.7 3.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) TMF_TATA_bd PF12325.8 ORY40936.1 - 6.1 7.1 19.8 0.76 10.0 6.2 3.2 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding GIT_CC PF16559.5 ORY40936.1 - 7.4 6.5 7.3 5.4 7.0 0.3 3.1 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Takusan PF04822.13 ORY40936.1 - 7.4 6.5 9.6 0.8 9.6 0.9 3.1 2 1 1 3 3 3 0 Takusan DASH_Dam1 PF08653.10 ORY40936.1 - 7.9 6.4 7.4 2.5 8.0 0.2 3.6 4 1 0 4 4 4 0 DASH complex subunit Dam1 YabA PF06156.13 ORY40936.1 - 9 7.0 17.6 23 5.7 4.4 4.3 1 1 3 4 4 4 0 Initiation control protein YabA cNMP_binding PF00027.29 ORY40937.1 - 6.1e-15 55.1 0.0 1.1e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CRAL_TRIO PF00650.20 ORY40938.1 - 0.035 13.8 0.0 0.23 11.1 0.0 2.1 1 1 0 1 1 1 0 CRAL/TRIO domain GDPD PF03009.17 ORY40940.1 - 7.4e-46 157.0 0.0 1.1e-45 156.5 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family NAD_Gly3P_dh_N PF01210.23 ORY40941.1 - 4.2e-50 169.8 0.3 7.3e-50 169.0 0.3 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 ORY40941.1 - 7.6e-50 168.9 0.0 1.5e-49 167.9 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus CRAL_TRIO PF00650.20 ORY40942.1 - 7.9e-27 93.9 0.0 1.1e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORY40942.1 - 3.3e-07 30.4 0.0 5.8e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ORY40942.1 - 0.0026 17.9 0.0 0.0039 17.3 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Ribosomal_S24e PF01282.19 ORY40943.1 - 0.034 14.1 0.0 0.041 13.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S24e Ribosomal_S24e PF01282.19 ORY40946.1 - 0.034 14.1 0.0 0.041 13.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S24e zf-C2H2 PF00096.26 ORY40948.1 - 3e-12 46.3 23.0 0.00097 19.5 3.6 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY40948.1 - 2.1e-11 43.7 15.0 0.0006 20.1 0.2 4.3 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY40948.1 - 2.9e-11 43.2 23.1 0.0073 17.1 0.5 4.5 4 1 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY40948.1 - 1.7e-06 27.9 17.4 1.2e-05 25.1 0.5 4.4 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORY40948.1 - 3.3e-05 23.5 15.4 0.044 13.5 1.1 4.2 4 0 0 4 4 4 2 zinc-finger C2H2-type Zn_ribbon_SprT PF17283.2 ORY40948.1 - 0.0045 16.9 0.5 0.0045 16.9 0.5 3.3 3 0 0 3 3 3 1 SprT-like zinc ribbon domain zf-met PF12874.7 ORY40948.1 - 0.01 16.2 13.1 0.13 12.7 0.6 4.0 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 ORY40948.1 - 0.025 14.9 5.0 0.077 13.3 1.3 2.3 2 0 0 2 2 2 0 C2H2-type zinc ribbon zf_C2H2_ZHX PF18387.1 ORY40948.1 - 0.046 13.4 1.6 0.046 13.4 1.6 3.6 2 1 2 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF629 PF04780.12 ORY40948.1 - 0.048 12.2 0.0 0.048 12.2 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF629) DUF4379 PF14311.6 ORY40948.1 - 0.049 14.0 7.1 5.1 7.5 0.7 3.1 3 0 0 3 3 3 0 Probable Zinc-ribbon domain zf-C2H2_jaz PF12171.8 ORY40948.1 - 0.091 13.1 14.4 8.6 6.8 0.3 4.7 5 0 0 5 5 4 0 Zinc-finger double-stranded RNA-binding HalOD2 PF18547.1 ORY40948.1 - 0.12 12.4 13.6 0.25 11.3 0.6 3.7 3 1 0 3 3 3 0 Halobacterial output domain 2 CLU PF13236.6 ORY40948.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Clustered mitochondria zf-C2HE PF16278.5 ORY40948.1 - 0.18 12.3 0.6 0.18 12.3 0.6 3.5 2 1 2 4 4 3 0 C2HE / C2H2 / C2HC zinc-binding finger Ribosomal_L37ae PF01780.19 ORY40948.1 - 0.61 10.2 14.0 3.1 7.9 0.1 3.6 2 1 2 4 4 4 0 Ribosomal L37ae protein family zf-C2H2_3rep PF18868.1 ORY40948.1 - 0.79 10.4 10.8 5.8 7.6 3.4 3.2 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats DNA_RNApol_7kD PF03604.13 ORY40948.1 - 0.86 9.3 8.9 25 4.7 0.2 4.2 4 0 0 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit C1_4 PF07975.12 ORY40948.1 - 0.96 9.7 12.2 1.3 9.4 2.1 3.7 2 1 2 4 4 4 0 TFIIH C1-like domain zf-BED PF02892.15 ORY40948.1 - 1.8 8.6 12.1 20 5.3 0.4 3.5 3 1 0 3 3 3 0 BED zinc finger Coiled PF05710.12 ORY40948.1 - 1.9 9.3 5.2 0.57 11.0 1.6 2.0 1 1 1 2 2 2 0 Coiled coil CpXC PF14353.6 ORY40948.1 - 2.1 8.4 8.9 4.3 7.4 0.2 3.4 3 1 0 3 3 3 0 CpXC protein zf-LYAR PF08790.11 ORY40948.1 - 2.7 8.0 13.4 6 6.9 0.1 3.9 4 0 0 4 4 3 0 LYAR-type C2HC zinc finger Zn_ribbon_recom PF13408.6 ORY40948.1 - 3 8.4 14.9 0.36 11.4 1.1 3.4 3 1 0 3 3 3 0 Recombinase zinc beta ribbon domain Zn_Tnp_IS1595 PF12760.7 ORY40948.1 - 4.7 7.3 13.3 5 7.2 3.5 3.2 3 0 0 3 3 3 0 Transposase zinc-ribbon domain zf_UBZ PF18439.1 ORY40948.1 - 5.1 6.8 13.6 5 6.8 0.1 4.0 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Mut7-C PF01927.16 ORY40948.1 - 6.4 6.9 11.7 7.7 6.6 0.1 3.0 2 1 0 2 2 2 0 Mut7-C RNAse domain Tetraspanin PF00335.20 ORY40949.1 - 7.9e-11 42.1 6.5 1e-10 41.7 6.5 1.1 1 0 0 1 1 1 1 Tetraspanin family CD20 PF04103.15 ORY40949.1 - 0.0034 17.5 4.7 0.029 14.5 2.2 2.1 2 0 0 2 2 2 1 CD20-like family Claudin_2 PF13903.6 ORY40949.1 - 0.0064 16.3 4.0 0.047 13.5 2.4 2.0 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF308 PF03729.13 ORY40949.1 - 0.14 12.5 15.1 1.2 9.5 8.4 2.2 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) DUF2417 PF10329.9 ORY40949.1 - 0.8 9.1 0.0 0.8 9.1 0.0 2.2 2 1 1 3 3 3 0 Region of unknown function (DUF2417) Phage_holin_3_6 PF07332.11 ORY40949.1 - 1 9.4 8.0 3.5 7.7 5.3 2.1 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Tetraspanin PF00335.20 ORY40950.1 - 1.4e-12 47.8 8.4 3e-12 46.7 8.6 1.5 1 1 0 1 1 1 1 Tetraspanin family DUF3472 PF11958.8 ORY40951.1 - 1.5e-39 136.3 10.1 3e-21 76.6 3.9 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3472) Cas9_PI2 PF18070.1 ORY40951.1 - 0.12 13.2 0.2 20 6.0 0.0 3.2 3 0 0 3 3 3 0 CRISPR-Cas9 PI domain MG4 PF17789.1 ORY40951.1 - 0.13 12.5 0.1 0.13 12.5 0.1 2.9 4 0 0 4 4 4 0 Macroglobulin domain MG4 Big_1 PF02369.16 ORY40952.1 - 0.001 19.0 0.3 0.009 16.0 0.0 2.7 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 1) Ricin_B_lectin PF00652.22 ORY40952.1 - 0.0014 18.9 1.1 0.07 13.4 0.0 3.1 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain DUF3472 PF11958.8 ORY40952.1 - 0.037 14.5 0.1 0.06 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3472) Nop PF01798.18 ORY40953.1 - 2.1e-85 285.9 0.1 3.6e-85 285.1 0.1 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin RNA_polI_A34 PF08208.11 ORY40953.1 - 3.7 7.6 39.2 6.6 6.8 39.2 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 PIP5K PF01504.18 ORY40954.1 - 2.6e-77 259.7 0.0 4.5e-47 160.6 0.1 2.1 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase RNA_pol_Rpb1_5 PF04998.17 ORY40955.1 - 5.2e-101 337.6 0.0 8.2e-101 336.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 ORY40955.1 - 3.1e-97 325.7 0.1 4.5e-97 325.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_6 PF04992.14 ORY40955.1 - 5.2e-64 215.6 0.1 1.3e-63 214.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_2 PF00623.20 ORY40955.1 - 9.2e-59 198.4 0.5 7.9e-57 192.1 0.1 2.7 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 ORY40955.1 - 7.5e-50 168.9 0.0 1.8e-49 167.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 ORY40955.1 - 4e-36 123.2 0.2 1.1e-35 121.9 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_7 PF04990.12 ORY40955.1 - 1.1e-23 83.8 0.0 2.7e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_R PF05001.13 ORY40955.1 - 2.4e-10 40.2 390.2 0.15 12.5 11.6 18.6 2 1 24 28 28 28 25 RNA polymerase Rpb1 C-terminal repeat MFS_1 PF07690.16 ORY40956.1 - 1.6e-41 142.5 62.7 7e-34 117.3 32.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily E1-E2_ATPase PF00122.20 ORY40958.1 - 1.1e-44 152.1 7.6 2.7e-44 150.9 3.4 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORY40958.1 - 1.4e-33 116.9 0.5 3.6e-33 115.6 0.5 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 ORY40958.1 - 3.2e-30 104.3 2.3 5.7e-14 52.3 0.2 3.8 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 ORY40958.1 - 0.0026 17.5 3.1 0.089 12.5 0.9 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase CorA PF01544.18 ORY40958.1 - 0.13 11.6 1.0 0.23 10.8 1.0 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein OPT PF03169.15 ORY40959.1 - 2e-119 400.0 59.6 2.3e-119 399.8 59.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Cmc1 PF08583.10 ORY40960.1 - 4.8e-12 45.7 2.8 6e-12 45.4 2.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 ORY40960.1 - 0.013 15.6 0.2 0.027 14.6 0.2 1.6 1 0 0 1 1 1 0 CHCH domain E1-E2_ATPase PF00122.20 ORY40961.1 - 1.2e-25 90.1 0.0 2.8e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase P5-ATPase PF12409.8 ORY40961.1 - 1.6e-18 67.0 0.9 4.6e-17 62.3 0.0 2.7 2 0 0 2 2 2 1 P5-type ATPase cation transporter Hydrolase PF00702.26 ORY40961.1 - 6.7e-14 52.7 0.1 2.9e-06 27.7 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 ORY40961.1 - 0.00055 19.7 2.7 0.00055 19.7 2.7 2.4 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORY40961.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) DUF2627 PF11118.8 ORY40961.1 - 0.13 12.8 0.2 0.33 11.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Oxidored_q6 PF01058.22 ORY40962.1 - 1e-22 80.4 0.2 1.5e-22 79.8 0.2 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Ribosomal_L1 PF00687.21 ORY40963.1 - 1.6e-47 161.9 3.4 2.5e-47 161.3 3.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family RRM_1 PF00076.22 ORY40963.1 - 1.5e-12 47.1 0.0 4.9e-12 45.5 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S30 PF01577.16 ORY40963.1 - 1 8.9 4.1 1.9 8.0 4.1 1.4 1 0 0 1 1 1 0 Potyvirus P1 protease Cornifin PF02389.15 ORY40964.1 - 0.0013 18.9 0.0 0.53 10.5 0.0 2.0 1 1 1 2 2 2 2 Cornifin (SPRR) family AvrRpt-cleavage PF05627.11 ORY40964.1 - 0.047 13.1 13.7 1.3e+02 2.1 0.1 7.9 4 4 4 8 8 8 0 Cleavage site for pathogenic type III effector avirulence factor Avr DCD PF06559.11 ORY40964.1 - 0.13 11.0 0.1 50 2.5 0.0 3.0 1 1 2 3 3 3 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) Rpn3_C PF08375.11 ORY40966.1 - 2.7e-22 79.0 0.5 1.1e-21 77.0 0.3 2.0 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 ORY40966.1 - 6.6e-22 78.0 1.3 5.3e-21 75.1 0.1 2.5 2 1 0 2 2 2 1 PCI domain Helicase_C PF00271.31 ORY40967.1 - 2e-28 98.9 1.2 3.7e-28 98.1 0.5 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY40967.1 - 4.2e-17 62.5 0.0 6.6e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Phage_integrase PF00589.22 ORY40967.1 - 0.016 15.0 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 Phage integrase family WD40 PF00400.32 ORY40968.1 - 6.9e-31 105.8 10.6 0.0014 19.4 0.0 11.0 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY40968.1 - 4.9e-08 33.2 1.4 0.065 13.5 0.0 5.5 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Proteasome_A_N PF10584.9 ORY40968.1 - 0.12 12.0 0.0 95 2.8 0.0 3.9 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature zf-H2C2_2 PF13465.6 ORY40970.1 - 4.7e-18 64.7 21.1 3.7e-06 27.1 6.5 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORY40970.1 - 1.9e-11 43.7 17.0 0.0001 22.6 2.4 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY40970.1 - 4e-08 33.4 17.2 0.00094 19.8 2.3 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger GAGA PF09237.11 ORY40970.1 - 0.00048 19.9 1.7 0.048 13.5 0.0 2.4 1 1 2 3 3 3 2 GAGA factor zf-Paramyx-P PF13008.7 ORY40970.1 - 0.001 18.4 5.8 0.079 12.4 0.2 3.1 3 0 0 3 3 3 2 Zinc-binding domain of Paramyxoviridae V protein zf-C2H2_jaz PF12171.8 ORY40970.1 - 0.0014 18.8 5.8 0.79 10.1 0.3 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 ORY40970.1 - 0.0055 16.4 9.4 0.79 9.5 2.1 3.1 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2HE PF16278.5 ORY40970.1 - 0.021 15.3 16.6 0.18 12.3 3.5 3.1 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_5 PF13909.6 ORY40970.1 - 0.038 13.7 2.9 0.038 13.7 2.9 3.9 4 1 0 4 4 4 0 C2H2-type zinc-finger domain TF_Zn_Ribbon PF08271.12 ORY40970.1 - 0.082 12.4 3.8 3.1 7.4 0.7 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding zf-met PF12874.7 ORY40970.1 - 0.19 12.2 13.4 0.71 10.3 0.7 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type NOA36 PF06524.12 ORY40970.1 - 0.21 10.9 7.7 0.33 10.2 7.7 1.3 1 1 0 1 1 1 0 NOA36 protein DUF3268 PF11672.8 ORY40970.1 - 0.39 11.1 4.9 0.87 9.9 0.6 2.1 1 1 1 2 2 2 0 zinc-finger-containing domain zf-C3HC PF07967.13 ORY40970.1 - 0.45 10.6 7.0 0.61 10.1 7.0 1.3 1 1 0 1 1 1 0 C3HC zinc finger-like Elf1 PF05129.13 ORY40970.1 - 0.46 10.6 11.3 1.7 8.7 5.7 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2_7 PF15269.6 ORY40970.1 - 0.48 10.5 13.2 0.6 10.2 1.0 3.1 1 1 2 3 3 3 0 Zinc-finger Zn_Tnp_IS1595 PF12760.7 ORY40970.1 - 0.95 9.5 12.0 1.5 8.9 7.8 2.4 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-C2H2_6 PF13912.6 ORY40970.1 - 1.1 9.3 0.1 1.1 9.3 0.1 4.1 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_9 PF16293.5 ORY40970.1 - 1.1 9.2 6.6 1.7 8.5 0.9 2.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) PhnA_Zn_Ribbon PF08274.12 ORY40970.1 - 5 7.2 11.2 6 6.9 4.5 2.7 2 2 0 2 2 2 0 PhnA Zinc-Ribbon zf-C2H2_4 PF13894.6 ORY40971.1 - 2.3e-06 27.9 21.6 0.0034 18.1 1.2 3.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY40971.1 - 8.5e-06 25.6 15.0 0.00012 22.0 1.3 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 ORY40971.1 - 5.2e-05 23.9 1.3 5.2e-05 23.9 1.3 1.8 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2 PF00096.26 ORY40971.1 - 0.00031 21.0 22.5 0.01 16.2 1.7 4.2 4 1 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 ORY40971.1 - 0.009 16.3 4.3 6.8 7.1 0.0 2.8 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) PHD_Oberon PF07227.11 ORY40971.1 - 0.0098 15.8 0.3 4.4 7.2 0.0 2.2 2 0 0 2 2 2 2 PHD - plant homeodomain finger protein zf_C2H2_ZHX PF18387.1 ORY40971.1 - 0.12 12.1 0.5 0.12 12.1 0.5 2.1 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Actin_micro PF17003.5 ORY40971.1 - 0.33 10.1 6.8 1.7 7.7 0.2 2.3 2 1 0 2 2 2 0 Putative actin-like family DZR PF12773.7 ORY40971.1 - 0.5 10.4 4.8 1.7 8.8 0.8 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf-C2H2_jaz PF12171.8 ORY40971.1 - 1.3 9.4 0.0 1.3 9.4 0.0 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 ORY40971.1 - 3.9 8.1 21.7 0.59 10.7 1.4 4.1 4 0 0 4 4 4 0 Zinc-finger double domain LRR_8 PF13855.6 ORY40972.1 - 1.9e-15 56.3 1.3 2.6e-07 30.3 0.0 2.0 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY40972.1 - 3.3e-08 33.7 5.1 0.00069 20.0 0.2 2.6 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY40972.1 - 1.3e-05 25.1 5.9 6.2 7.8 0.1 4.4 3 1 1 4 4 4 3 Leucine Rich Repeat LRR_9 PF14580.6 ORY40972.1 - 0.077 12.5 0.2 0.13 11.7 0.1 1.3 1 1 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 ORY40972.1 - 0.12 12.5 1.2 32 4.9 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich repeat Glyco_trans_1_2 PF13524.6 ORY40973.1 - 2.2e-07 31.1 1.5 3.9e-07 30.4 1.5 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 ATP-cone PF03477.16 ORY40973.1 - 7e-05 23.3 0.4 0.00013 22.4 0.4 1.4 1 0 0 1 1 1 1 ATP cone domain Ribonuc_L-PSP PF01042.21 ORY40974.1 - 2.3e-28 98.7 0.0 2.6e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP VMA21 PF09446.10 ORY40975.1 - 7.1e-11 42.0 9.0 1.2e-10 41.4 9.0 1.3 1 1 0 1 1 1 1 VMA21-like domain IBR PF01485.21 ORY40976.1 - 2.6e-19 69.2 44.8 1e-09 38.5 5.1 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 ORY40976.1 - 6.5e-06 25.9 4.7 6.5e-06 25.9 4.7 4.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY40976.1 - 0.00028 20.7 4.6 0.00028 20.7 4.6 4.6 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY40976.1 - 0.00029 20.8 5.8 0.00029 20.8 5.8 3.9 3 1 0 3 3 3 1 RING-type zinc-finger zf-Nse PF11789.8 ORY40976.1 - 0.0033 17.2 1.5 0.024 14.4 1.5 2.5 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.6 ORY40976.1 - 0.005 16.7 6.8 0.005 16.7 6.8 4.2 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY40976.1 - 0.0074 16.6 7.5 0.0074 16.6 7.5 3.7 3 0 0 3 3 3 2 Ring finger domain DUF4599 PF15371.6 ORY40976.1 - 0.09 13.3 1.2 0.99 10.0 0.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4599) FancD2 PF14631.6 ORY40978.1 - 4.7e-161 538.0 42.4 5.1e-83 279.4 2.6 4.3 2 1 1 3 3 3 2 Fanconi anaemia protein FancD2 nuclease Tup_N PF08581.10 ORY40979.1 - 0.17 12.2 0.9 0.32 11.3 0.9 1.5 1 0 0 1 1 1 0 Tup N-terminal SPATA1_C PF15743.5 ORY40979.1 - 1.1 9.4 3.5 1.5 8.9 3.5 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus BTB PF00651.31 ORY40981.1 - 0.0074 16.5 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain MATH PF00917.26 ORY40981.1 - 0.1 12.8 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 MATH domain Podoplanin PF05808.11 ORY40982.1 - 0.11 12.6 0.3 0.13 12.3 0.3 1.1 1 0 0 1 1 1 0 Podoplanin CFEM PF05730.11 ORY40983.1 - 0.0027 17.8 2.3 0.0046 17.0 2.3 1.4 1 1 0 1 1 1 1 CFEM domain ECSIT_C PF14784.6 ORY40983.1 - 0.082 13.3 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein DUF2201_N PF13203.6 ORY40984.1 - 0.23 11.0 1.1 0.36 10.4 1.1 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain PepSY_2 PF13670.6 ORY40987.1 - 0.14 12.1 0.6 0.18 11.8 0.6 1.2 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain LRR_8 PF13855.6 ORY40989.1 - 8.3e-12 44.7 5.4 7.8e-06 25.6 1.4 2.1 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY40989.1 - 1.8e-09 37.7 12.0 0.00088 19.6 0.9 2.4 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY40989.1 - 4.7e-09 35.6 1.6 0.11 13.1 0.0 3.9 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.6 ORY40989.1 - 0.0044 17.0 5.6 7.6 6.9 0.1 3.9 4 0 0 4 4 4 2 Leucine Rich repeat Pkinase PF00069.25 ORY40990.1 - 7.3e-63 212.4 0.0 9e-63 212.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY40990.1 - 4.9e-49 166.9 0.0 6.6e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY40990.1 - 0.00011 21.7 0.1 0.00037 19.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORY40990.1 - 0.00014 20.8 0.0 0.00022 20.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY40990.1 - 0.056 12.4 0.1 0.067 12.1 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain TB2_DP1_HVA22 PF03134.19 ORY40994.1 - 8.5e-18 64.1 4.5 8.5e-18 64.1 4.5 1.8 2 0 0 2 2 2 1 TB2/DP1, HVA22 family VIT1 PF01988.19 ORY40994.1 - 1.7 8.4 3.5 1.9 8.3 2.7 1.5 1 1 0 1 1 1 0 VIT family LRR_8 PF13855.6 ORY40995.1 - 1e-18 66.9 29.3 1.8e-08 34.0 5.4 2.9 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY40995.1 - 5e-11 42.7 20.6 7.2e-06 26.3 2.6 4.8 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY40995.1 - 8.2e-07 28.7 26.4 0.38 11.5 2.1 7.3 8 0 0 8 8 8 5 Leucine Rich Repeat F-box PF00646.33 ORY40995.1 - 2.3e-05 24.2 1.1 2.3e-05 24.2 1.1 3.0 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 ORY40995.1 - 0.0036 17.1 2.9 0.0045 16.9 1.5 1.9 2 0 0 2 2 2 1 F-box-like LRR_9 PF14580.6 ORY40995.1 - 0.69 9.4 6.4 7.4 6.0 0.8 2.3 1 1 0 2 2 2 0 Leucine-rich repeat Peptidase_C50 PF03568.17 ORY40996.1 - 5e-79 266.3 0.8 1.3e-77 261.6 0.1 3.4 2 1 0 2 2 2 1 Peptidase family C50 TPR_12 PF13424.6 ORY40996.1 - 0.00021 21.5 6.1 2 8.7 0.9 7.3 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY40996.1 - 0.0003 20.7 0.1 15 6.0 0.0 5.7 7 0 0 7 7 7 2 Tetratricopeptide repeat SPO22 PF08631.10 ORY40996.1 - 0.0072 15.8 2.6 0.018 14.6 0.2 2.9 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like DnaB_C PF03796.15 ORY40996.1 - 0.13 11.5 0.2 0.34 10.2 0.0 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Peptidase_S9_N PF02897.15 ORY40997.1 - 1e-105 353.9 0.2 1.9e-105 353.0 0.2 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 ORY40997.1 - 5.5e-18 65.2 0.1 5.2e-10 39.2 0.0 3.7 3 1 1 4 4 4 3 Prolyl oligopeptidase family CBM65_1 PF18259.1 ORY40997.1 - 0.041 14.0 0.0 0.09 12.9 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate binding module 65 domain 1 CFEM PF05730.11 ORY40998.1 - 0.00036 20.5 3.1 0.00036 20.5 3.1 3.1 3 1 1 4 4 4 1 CFEM domain Ank_2 PF12796.7 ORY41000.1 - 1.5e-21 76.7 5.9 3.5e-11 43.5 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY41000.1 - 8.1e-14 50.4 1.6 0.023 15.2 0.1 6.6 7 0 0 7 7 7 3 Ankyrin repeat Ank_4 PF13637.6 ORY41000.1 - 4e-12 46.4 2.4 8e-06 26.3 0.5 4.4 2 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY41000.1 - 4e-09 36.5 9.5 0.0045 17.4 0.1 6.0 6 1 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 ORY41000.1 - 1.4e-05 25.3 4.4 0.024 15.0 0.5 4.5 4 2 2 6 6 6 2 Ankyrin repeats (many copies) DUF3447 PF11929.8 ORY41000.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3447) DUF2786 PF10979.8 ORY41000.1 - 0.035 14.0 3.3 2.9 7.9 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2786) Glyco_hydro_18 PF00704.28 ORY41001.1 - 1.3e-76 258.3 3.1 1.3e-76 258.3 3.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Hydrolase_like PF13242.6 ORY41002.1 - 1.3e-17 63.6 0.2 2.7e-17 62.6 0.2 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 ORY41002.1 - 4.2e-12 46.1 0.0 8.8e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY41002.1 - 6.1e-09 36.5 0.4 2.4e-08 34.6 0.4 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY41002.1 - 2.4e-07 31.0 0.0 1.2e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase MFS_MOT1 PF16983.5 ORY41004.1 - 0.025 15.0 0.7 0.025 15.0 0.7 2.8 2 1 1 3 3 3 0 Molybdate transporter of MFS superfamily MpPF26 PF07666.11 ORY41004.1 - 0.063 13.4 21.3 0.036 14.2 2.6 3.3 3 0 0 3 3 3 0 M penetrans paralogue family 26 DUF2627 PF11118.8 ORY41004.1 - 2.4 8.8 6.0 1.1 9.9 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2627) Fungal_trans PF04082.18 ORY41005.1 - 3e-06 26.5 0.1 5e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY41005.1 - 0.00028 20.9 6.5 0.0006 19.9 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DFP PF04127.15 ORY41006.1 - 1.7e-18 67.1 0.0 9.3e-12 45.2 0.0 2.3 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Sec63 PF02889.16 ORY41007.1 - 7.8e-120 398.8 0.0 1.5e-77 260.2 0.1 3.7 2 1 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 ORY41007.1 - 2.9e-52 177.0 0.6 5.7e-26 91.3 0.6 4.2 5 0 0 5 5 5 2 DEAD/DEAH box helicase ResIII PF04851.15 ORY41007.1 - 2.7e-28 99.1 0.0 6e-14 52.4 0.1 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORY41007.1 - 1e-16 61.3 0.0 1.9e-06 28.2 0.0 3.6 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 ORY41007.1 - 5.3e-07 30.0 0.4 0.022 15.1 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 ORY41007.1 - 0.0066 16.9 0.3 5.6 7.4 0.0 3.4 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 ORY41007.1 - 0.014 14.4 0.0 1.7 7.6 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 ORY41007.1 - 0.031 14.0 0.3 2.4 7.8 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein PhoH PF02562.16 ORY41007.1 - 0.054 13.0 0.0 7.1 6.0 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein DUF2541 PF10807.8 ORY41007.1 - 0.08 13.0 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2541) UvrD-helicase PF00580.21 ORY41007.1 - 0.11 12.0 0.7 1.6 8.2 0.2 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Thymidylat_synt PF00303.19 ORY41008.1 - 1.3e-100 335.9 0.0 1.6e-100 335.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase adh_short_C2 PF13561.6 ORY41009.1 - 2.6e-63 213.7 3.5 3e-63 213.5 3.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY41009.1 - 4.8e-57 192.6 3.1 5.9e-57 192.3 3.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY41009.1 - 2.9e-15 56.6 0.8 4.3e-15 56.1 0.8 1.2 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 ORY41009.1 - 0.00026 20.4 0.4 0.00045 19.6 0.4 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 ORY41009.1 - 0.014 14.9 1.6 0.027 13.9 1.6 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family B12-binding PF02310.19 ORY41009.1 - 0.068 13.2 0.7 0.23 11.5 0.3 1.9 2 0 0 2 2 2 0 B12 binding domain DUF3290 PF11694.8 ORY41011.1 - 0.32 11.0 0.1 0.44 10.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) LRR_8 PF13855.6 ORY41012.1 - 4.3e-17 61.6 26.9 2e-07 30.7 6.5 4.4 2 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 ORY41012.1 - 1.7e-13 50.5 30.9 1.9e-07 31.3 3.8 4.8 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY41012.1 - 5.2e-08 32.4 24.4 0.064 13.8 0.3 7.8 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_9 PF14580.6 ORY41012.1 - 0.031 13.8 9.8 0.061 12.8 1.4 3.3 2 1 0 3 3 3 0 Leucine-rich repeat F-box-like PF12937.7 ORY41012.1 - 0.043 13.7 0.1 0.092 12.7 0.1 1.5 1 0 0 1 1 1 0 F-box-like LRR_6 PF13516.6 ORY41012.1 - 0.045 13.8 0.7 0.045 13.8 0.7 7.0 8 0 0 8 8 8 0 Leucine Rich repeat DPPIV_N PF00930.21 ORY41012.1 - 0.18 10.6 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region adh_short_C2 PF13561.6 ORY41013.1 - 3.3e-62 210.1 3.8 3.9e-62 209.9 3.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY41013.1 - 5.6e-57 192.4 3.6 6.8e-57 192.1 3.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY41013.1 - 2.4e-15 56.9 0.7 3.5e-15 56.4 0.7 1.2 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 ORY41013.1 - 0.00027 20.4 0.6 0.00047 19.6 0.6 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 ORY41013.1 - 0.012 15.1 1.8 0.023 14.1 1.8 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family B12-binding PF02310.19 ORY41013.1 - 0.06 13.4 0.6 0.16 12.0 0.3 1.8 2 0 0 2 2 2 0 B12 binding domain DUF460 PF04312.13 ORY41013.1 - 0.069 12.8 0.2 0.12 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF460) p450 PF00067.22 ORY41014.1 - 6.2e-29 101.1 0.0 6.6e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SHQ1 PF04925.15 ORY41015.1 - 0.12 12.0 0.0 0.13 11.8 0.0 1.0 1 0 0 1 1 1 0 SHQ1 protein p450 PF00067.22 ORY41016.1 - 6.2e-79 265.9 0.0 8.2e-79 265.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APH PF01636.23 ORY41017.1 - 6.8e-12 45.8 0.0 8.8e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY41017.1 - 0.0013 18.4 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 ORY41017.1 - 0.0022 17.4 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Methyltransf_16 PF10294.9 ORY41019.1 - 2.4e-09 37.2 0.0 3e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 ORY41019.1 - 0.00022 21.1 0.0 0.00033 20.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY41019.1 - 0.0015 19.2 0.0 0.006 17.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ORY41019.1 - 0.024 14.0 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Sulfatase PF00884.23 ORY41020.1 - 1.2e-59 202.3 0.3 1.5e-59 201.9 0.3 1.1 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 ORY41020.1 - 3.6e-07 30.4 0.3 7.6e-07 29.3 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Methyltransf_16 PF10294.9 ORY41021.1 - 2.4e-07 30.7 0.0 3.4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase eIF3g PF12353.8 ORY41022.1 - 1.9e-36 125.2 0.2 2.8e-36 124.6 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 ORY41022.1 - 5.5e-16 58.2 0.0 1.3e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HLH PF00010.26 ORY41024.1 - 3.8e-07 30.0 1.4 6.7e-07 29.2 1.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Caudo_TAP PF02413.17 ORY41024.1 - 0.45 10.7 3.5 1 9.5 1.3 2.2 1 1 1 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK HLH PF00010.26 ORY41026.1 - 6.9e-06 25.9 0.6 1.7e-05 24.7 0.6 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 ORY41027.1 - 2.2e-08 33.9 4.0 4.9e-08 32.8 4.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF1640 PF07798.11 ORY41027.1 - 1.5 8.8 11.3 2.3 8.2 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) HLH PF00010.26 ORY41028.1 - 1.3e-05 25.1 0.2 2.6e-05 24.1 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HLH PF00010.26 ORY41029.1 - 4.6e-11 42.5 0.1 8.6e-11 41.6 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain FAM76 PF16046.5 ORY41029.1 - 0.87 8.9 5.9 1.2 8.4 5.9 1.1 1 0 0 1 1 1 0 FAM76 protein HLH PF00010.26 ORY41030.1 - 1.7e-07 31.1 0.3 3.5e-07 30.1 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain PH PF00169.29 ORY41031.1 - 0.00013 22.4 0.2 0.005 17.3 0.0 2.8 3 0 0 3 3 3 1 PH domain DUF5098 PF17023.5 ORY41031.1 - 0.0034 16.4 7.2 1.2 8.0 5.3 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF5098) DUF3597 PF12200.8 ORY41031.1 - 0.0065 17.0 0.2 0.016 15.7 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3597) Bacillus_HBL PF05791.11 ORY41031.1 - 0.012 15.4 1.4 0.11 12.3 0.2 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) FCH PF00611.23 ORY41031.1 - 0.031 14.5 0.4 0.13 12.6 0.1 2.2 2 1 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain EloA-BP1 PF15870.5 ORY41031.1 - 0.11 12.7 4.2 2.1 8.6 4.2 2.2 1 1 0 1 1 1 0 ElonginA binding-protein 1 Profilin PF00235.19 ORY41032.1 - 5.7e-22 78.3 0.1 6.6e-22 78.1 0.1 1.0 1 0 0 1 1 1 1 Profilin XPG_N PF00752.17 ORY41033.1 - 5.7e-35 119.8 0.0 9.5e-35 119.1 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 ORY41033.1 - 4.3e-32 110.3 0.0 7.9e-32 109.5 0.0 1.5 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 ORY41033.1 - 5.9e-06 26.8 0.0 1.3e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold A_deamin PF02137.18 ORY41034.1 - 1.4e-67 228.5 0.0 1.6e-67 228.3 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF1325 PF07039.11 ORY41036.1 - 6.6e-29 100.6 0.0 1.1e-28 99.9 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 ORY41036.1 - 0.0012 18.6 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain LBR_tudor PF09465.10 ORY41036.1 - 0.0018 18.0 0.0 0.004 16.9 0.0 1.5 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain TUDOR_5 PF18359.1 ORY41036.1 - 0.0098 15.6 0.1 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 Histone methyltransferase Tudor domain 1 zf-MYND PF01753.18 ORY41037.1 - 1.3e-07 31.6 16.2 3.2e-07 30.3 16.2 1.7 1 0 0 1 1 1 1 MYND finger DNApol_Exo PF18136.1 ORY41038.1 - 1.2e-89 300.2 0.1 2.3e-89 299.3 0.1 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 ORY41038.1 - 1.2e-31 110.1 0.0 1.1e-30 107.0 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase family A zf-RING_2 PF13639.6 ORY41039.1 - 5.1e-11 42.7 32.0 4.8e-05 23.6 5.2 3.7 3 0 0 3 3 3 3 Ring finger domain zf-rbx1 PF12678.7 ORY41039.1 - 5.6e-05 23.3 31.1 0.033 14.5 7.1 4.2 3 2 0 3 3 3 3 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORY41039.1 - 0.00035 20.3 34.5 0.053 13.4 6.9 4.2 3 3 0 3 3 3 3 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY41039.1 - 0.0061 16.3 18.1 0.041 13.6 0.3 4.6 5 0 0 5 5 5 3 RING-like zinc finger zf-ANAPC11 PF12861.7 ORY41039.1 - 0.007 16.4 19.9 0.19 11.8 1.6 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 ORY41039.1 - 0.0072 16.2 26.8 0.096 12.6 2.1 3.7 3 0 0 3 3 3 2 PHD-finger zf-RING_5 PF14634.6 ORY41039.1 - 0.026 14.5 34.4 0.098 12.6 1.8 4.6 4 2 1 5 5 5 0 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY41039.1 - 0.028 14.3 23.9 1.2 9.0 0.1 4.2 3 2 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 ORY41039.1 - 0.03 14.2 2.4 0.03 14.2 2.4 4.9 3 2 2 5 5 5 0 Zinc finger, C3HC4 type (RING finger) Birna_VP5 PF03042.14 ORY41039.1 - 0.071 13.1 0.3 0.16 12.0 0.3 1.6 1 0 0 1 1 1 0 Birnavirus VP5 protein zf-RING_UBOX PF13445.6 ORY41039.1 - 0.08 13.0 26.9 0.14 12.2 0.8 5.2 4 1 1 5 5 5 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 ORY41039.1 - 0.12 12.0 27.6 0.42 10.3 7.8 4.1 3 2 0 3 3 3 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 ORY41039.1 - 0.38 10.8 22.5 0.12 12.4 2.6 4.2 4 0 0 4 4 4 0 Zinc-finger FANCL_C PF11793.8 ORY41039.1 - 4.7 7.5 25.7 0.78 10.0 0.5 4.9 3 3 1 4 4 4 0 FANCL C-terminal domain TctA PF01970.16 ORY41040.1 - 0.0025 16.6 4.9 0.0029 16.4 0.3 2.2 2 0 0 2 2 2 2 Tripartite tricarboxylate transporter TctA family SNF2_N PF00176.23 ORY41041.1 - 1.4e-26 93.0 0.2 3.1e-26 91.9 0.2 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY41041.1 - 5.6e-20 71.8 0.1 1.3e-18 67.4 0.0 3.2 4 0 0 4 4 4 1 Helicase conserved C-terminal domain VIGSSK PF14773.6 ORY41041.1 - 5.9e-10 39.1 0.3 5.9e-10 39.1 0.3 2.0 2 0 0 2 2 2 1 Helicase-associated putative binding domain, C-terminal ERCC3_RAD25_C PF16203.5 ORY41041.1 - 0.00056 19.2 0.0 0.0016 17.7 0.0 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase DUF3800 PF12686.7 ORY41041.1 - 0.11 13.2 0.1 17 6.0 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3800) Alk_phosphatase PF00245.20 ORY41042.1 - 5.8e-90 302.2 0.0 7.9e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase DUF5363 PF17320.2 ORY41042.1 - 0.21 11.5 0.1 25 4.9 0.0 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5363) adh_short PF00106.25 ORY41043.1 - 7.2e-34 116.9 0.3 4.9e-26 91.4 0.0 3.0 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY41043.1 - 4.8e-21 75.4 0.1 2.5e-16 60.0 0.0 2.5 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY41043.1 - 1.3e-09 38.2 0.0 2.3e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 ORY41043.1 - 0.00029 20.3 0.1 0.00078 18.9 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY41043.1 - 0.00074 19.0 0.4 0.013 15.0 0.4 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY41043.1 - 0.14 11.2 0.3 0.32 10.1 0.1 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein LRR_8 PF13855.6 ORY41044.1 - 6.4e-36 121.9 66.6 1.9e-08 34.0 3.8 9.5 4 3 5 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 ORY41044.1 - 8.7e-31 105.5 68.0 8.9e-06 26.0 0.3 10.5 8 1 1 10 10 10 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY41044.1 - 1.4e-10 40.2 77.9 0.057 14.0 0.6 17.5 16 2 1 17 17 17 7 Leucine Rich Repeat F-box PF00646.33 ORY41044.1 - 3.7e-10 39.4 0.1 0.00066 19.5 0.0 3.0 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 ORY41044.1 - 2e-09 37.2 1.3 0.008 16.0 0.0 3.9 4 0 0 4 4 4 2 F-box-like SAM_3 PF18016.1 ORY41044.1 - 0.014 15.2 0.1 28 4.6 0.0 3.7 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) DUF5612 PF18462.1 ORY41044.1 - 0.095 12.5 0.0 32 4.3 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5612) MIT PF04212.18 ORY41045.1 - 0.0011 19.0 0.2 0.0017 18.4 0.2 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Peptidase_C2 PF00648.21 ORY41046.1 - 4.2e-43 147.5 0.3 6.4e-43 146.9 0.3 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 ORY41046.1 - 2.6e-07 31.0 0.0 1.7e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 Calpain large subunit, domain III YbjN PF10722.9 ORY41046.1 - 0.032 14.3 0.1 0.28 11.2 0.1 2.3 2 0 0 2 2 2 0 Putative bacterial sensory transduction regulator PCI PF01399.27 ORY41047.1 - 3.6e-07 30.7 0.1 6.2e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 ORY41047.1 - 0.053 13.4 0.1 0.094 12.6 0.1 1.4 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain ATP-cone PF03477.16 ORY41047.1 - 0.091 13.3 0.3 0.22 12.1 0.3 1.6 1 0 0 1 1 1 0 ATP cone domain SIMPL PF04402.14 ORY41047.1 - 0.37 11.2 5.4 0.53 10.7 4.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF541) bZIP_1 PF00170.21 ORY41048.1 - 1.6e-09 37.7 2.9 1.6e-09 37.7 2.9 2.7 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 ORY41048.1 - 1.3e-05 25.2 8.0 1.3e-05 25.2 8.0 3.0 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORY41048.1 - 0.016 15.7 7.9 0.023 15.2 6.3 2.2 1 1 0 1 1 1 0 bZIP Maf transcription factor DUF4407 PF14362.6 ORY41048.1 - 0.033 13.5 3.0 0.05 13.0 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2284 PF10050.9 ORY41048.1 - 0.053 13.3 0.3 0.16 11.7 0.3 1.7 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) ABC_tran_CTD PF16326.5 ORY41048.1 - 0.089 13.1 4.4 0.1 12.9 1.4 2.7 2 1 0 2 2 2 0 ABC transporter C-terminal domain TMF_DNA_bd PF12329.8 ORY41048.1 - 0.47 10.5 7.8 3.2 7.8 0.1 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding BMFP PF04380.13 ORY41048.1 - 1 9.9 6.4 0.39 11.2 2.8 2.2 2 0 0 2 2 2 0 Membrane fusogenic activity DivIC PF04977.15 ORY41048.1 - 2.2 8.1 6.0 26 4.7 0.1 2.9 2 0 0 2 2 2 0 Septum formation initiator GvpL_GvpF PF06386.11 ORY41048.1 - 6.3 6.6 7.8 1.3e+02 2.3 7.8 2.2 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Cornichon PF03311.14 ORY41049.1 - 6.5e-49 165.3 14.4 7.4e-49 165.1 14.4 1.0 1 0 0 1 1 1 1 Cornichon protein zf-RING_2 PF13639.6 ORY41050.1 - 1.7e-05 25.1 5.3 1.7e-05 25.1 5.3 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 ORY41050.1 - 0.0049 16.6 1.2 0.0049 16.6 1.2 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 ORY41050.1 - 0.005 16.9 2.2 0.005 16.9 2.2 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 ORY41050.1 - 0.0089 15.9 2.0 0.0089 15.9 2.0 2.5 2 0 0 2 2 2 1 PHD-finger GAGA PF09237.11 ORY41050.1 - 0.21 11.4 4.3 4.5 7.2 0.2 2.4 1 1 1 2 2 2 0 GAGA factor Ost4 PF10215.9 ORY41050.1 - 0.3 10.9 3.6 0.45 10.4 3.6 1.3 1 0 0 1 1 1 0 Oligosaccaryltransferase zf-rbx1 PF12678.7 ORY41050.1 - 2.6 8.4 12.8 0.17 12.2 3.5 2.7 2 1 0 2 2 2 0 RING-H2 zinc finger domain Metallophos PF00149.28 ORY41051.1 - 5.4e-39 134.8 0.2 6.8e-39 134.5 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORY41051.1 - 1.1e-20 73.8 0.1 2.5e-20 72.7 0.1 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DUF2043 PF09740.9 ORY41052.1 - 2.8e-26 92.2 1.6 6.2e-26 91.1 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2043) 2-oxoacid_dh PF00198.23 ORY41053.1 - 7.3e-81 271.0 0.2 8.1e-81 270.9 0.2 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) MAM33 PF02330.16 ORY41055.1 - 4.7e-59 199.9 4.4 6.2e-59 199.5 4.4 1.2 1 0 0 1 1 1 1 Mitochondrial glycoprotein SHMT PF00464.19 ORY41056.1 - 4.1e-179 595.3 0.0 4.9e-179 595.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 ORY41056.1 - 1.5e-05 24.4 0.0 5.3e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 ORY41056.1 - 0.00041 19.8 0.0 0.00075 18.9 0.0 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family AbiJ_NTD3 PF18860.1 ORY41056.1 - 0.036 13.6 0.0 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 AbiJ N-terminal domain 3 LRR_4 PF12799.7 ORY41057.1 - 2.3e-08 34.2 29.7 0.00063 20.1 3.2 5.6 2 2 5 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY41057.1 - 1.4e-06 28.0 21.1 2.1e-06 27.4 3.3 4.3 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 ORY41057.1 - 9.8e-05 22.4 26.2 0.0041 17.5 0.5 8.5 5 3 2 7 7 7 1 Leucine Rich Repeat F-box PF00646.33 ORY41057.1 - 0.0018 18.1 0.8 0.0042 16.9 0.1 1.9 2 0 0 2 2 2 1 F-box domain ADIP PF11559.8 ORY41057.1 - 0.025 14.6 1.5 0.043 13.9 1.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding YabA PF06156.13 ORY41057.1 - 0.046 14.4 1.7 0.096 13.3 1.7 1.5 1 0 0 1 1 1 0 Initiation control protein YabA Hormone_1 PF00103.20 ORY41057.1 - 0.053 13.3 1.4 0.083 12.6 1.4 1.2 1 0 0 1 1 1 0 Somatotropin hormone family HALZ PF02183.18 ORY41057.1 - 0.054 13.7 0.7 0.23 11.7 0.2 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper RasGAP_C PF03836.15 ORY41057.1 - 0.064 13.4 0.9 0.12 12.6 0.9 1.3 1 0 0 1 1 1 0 RasGAP C-terminus ZapB PF06005.12 ORY41057.1 - 0.086 13.3 6.1 0.17 12.4 6.1 1.4 1 0 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 ORY41057.1 - 0.12 12.2 0.5 0.29 10.9 0.5 1.7 1 0 0 1 1 1 0 Septum formation initiator Cupin_8 PF13621.6 ORY41058.1 - 7.9e-18 65.1 0.0 1.5e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 ORY41058.1 - 6.5e-17 62.0 0.0 1.4e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Basic PF01586.16 ORY41058.1 - 0.22 12.7 0.3 0.22 12.7 0.3 2.4 2 1 0 2 2 2 0 Myogenic Basic domain SIR4_SID PF16991.5 ORY41058.1 - 3.5 7.7 0.0 3.5 7.7 0.0 3.2 3 0 0 3 3 3 0 Sir4 SID domain MRI PF15325.6 ORY41058.1 - 3.7 8.7 23.6 3.4 8.8 12.8 2.6 2 1 0 2 2 2 0 Modulator of retrovirus infection RAI16-like PF10257.9 ORY41059.1 - 2e-43 148.6 0.1 3.9e-43 147.7 0.1 1.4 1 1 0 1 1 1 1 Retinoic acid induced 16-like protein APG9 PF04109.16 ORY41060.1 - 4.8e-160 533.7 9.5 6e-160 533.4 9.5 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Ribophorin_II PF05817.14 ORY41061.1 - 1.6e-27 96.4 0.2 1.8e-27 96.2 0.2 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II LRR_8 PF13855.6 ORY41062.1 - 2.8e-13 49.4 22.6 1.3e-07 31.2 4.5 4.9 4 1 1 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 ORY41062.1 - 3.4e-11 43.2 22.2 0.00041 20.7 2.7 5.0 2 1 5 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY41062.1 - 1.9e-05 24.6 22.3 0.21 12.3 0.1 7.4 7 0 0 7 7 7 4 Leucine Rich Repeat F-box PF00646.33 ORY41062.1 - 0.00083 19.2 1.1 0.0021 17.9 1.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY41062.1 - 0.0056 16.6 0.6 0.013 15.3 0.6 1.7 1 0 0 1 1 1 1 F-box-like DUF4577 PF15145.6 ORY41063.1 - 1.3 9.1 4.1 5.5 7.0 2.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) polyprenyl_synt PF00348.17 ORY41064.1 - 2.1e-69 233.5 0.0 4.3e-69 232.4 0.0 1.6 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 ORY41064.1 - 0.013 15.2 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Svs_4_5_6 PF17381.2 ORY41064.1 - 0.85 10.6 0.1 0.85 10.6 0.1 2.5 2 0 0 2 2 2 0 Seminal vesicle secretory proteins 4/5/6 DUF829 PF05705.14 ORY41065.1 - 3.1e-27 96.0 0.0 3.8e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Ank_2 PF12796.7 ORY41066.1 - 1.1e-17 64.4 4.9 9.6e-09 35.7 0.1 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY41066.1 - 9e-05 22.7 1.6 0.11 12.9 0.2 3.9 2 1 2 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY41066.1 - 0.00061 20.3 0.7 0.024 15.2 0.3 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY41066.1 - 0.0015 18.9 1.2 6.8 7.6 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 ORY41066.1 - 0.011 16.1 2.2 8.9 7.0 0.0 3.5 3 1 1 4 4 4 0 Ankyrin repeat Vps5 PF09325.10 ORY41067.1 - 5.8e-49 166.8 3.5 8.5e-49 166.2 2.3 1.7 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 ORY41067.1 - 3.7e-27 94.5 0.0 7.7e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 PX domain Arfaptin PF06456.13 ORY41067.1 - 0.059 12.9 0.7 0.12 11.9 0.1 1.8 2 0 0 2 2 2 0 Arfaptin-like domain LRR_8 PF13855.6 ORY41068.1 - 1.4e-20 72.8 18.5 2.1e-08 33.8 0.6 4.6 2 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 ORY41068.1 - 4e-18 65.2 19.6 8.4e-06 26.0 1.1 5.6 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY41068.1 - 1.3e-11 43.3 21.9 0.42 11.4 0.0 9.0 8 1 1 9 9 9 5 Leucine Rich Repeat F-box PF00646.33 ORY41068.1 - 0.0078 16.1 0.3 0.018 14.9 0.3 1.6 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.6 ORY41068.1 - 0.012 15.6 16.0 18 5.7 0.0 7.6 8 0 0 8 8 8 0 Leucine Rich repeat zf-RING_2 PF13639.6 ORY41069.1 - 2.8e-06 27.6 7.9 2.8e-06 27.6 7.9 2.5 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 ORY41069.1 - 3.4e-05 23.9 5.1 0.00012 22.2 5.1 1.9 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 ORY41069.1 - 0.0001 22.2 3.1 0.00027 20.9 3.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 ORY41069.1 - 0.00011 22.5 5.6 0.00029 21.1 5.6 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain RINGv PF12906.7 ORY41069.1 - 0.077 13.1 11.8 0.017 15.3 7.6 2.2 2 0 0 2 2 2 0 RING-variant domain zf-C3HC4 PF00097.25 ORY41069.1 - 0.2 11.5 15.2 0.025 14.5 10.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 ORY41069.1 - 0.45 10.7 4.5 1.2 9.3 4.5 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING-like PF08746.11 ORY41069.1 - 0.71 10.2 12.6 0.089 13.1 7.9 2.0 2 0 0 2 2 2 0 RING-like domain PHD PF00628.29 ORY41069.1 - 1.3 8.9 6.6 5.3 7.0 6.6 2.1 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 ORY41069.1 - 1.8 8.5 6.5 4.5 7.2 6.5 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 ORY41069.1 - 2.2 8.0 4.7 6.5 6.5 4.7 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 ORY41069.1 - 2.6 7.9 10.5 0.98 9.3 7.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 ORY41069.1 - 3.6 7.4 5.7 8.9 6.2 5.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain AvrLm4-7 PF18661.1 ORY41070.1 - 0.07 14.2 0.5 0.2 12.7 0.2 1.8 1 1 1 2 2 2 0 Avirulence Effector AvrLm4-7 DUF4789 PF16033.5 ORY41071.1 - 0.029 14.9 0.8 0.04 14.4 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4789) WD40 PF00400.32 ORY41072.1 - 0.00082 20.1 5.5 12 6.9 0.1 6.1 7 0 0 7 7 7 2 WD domain, G-beta repeat URO-D PF01208.17 ORY41073.1 - 7.8e-89 298.2 0.1 2.9e-46 158.2 0.0 2.0 2 0 0 2 2 2 2 Uroporphyrinogen decarboxylase (URO-D) EF-hand_1 PF00036.32 ORY41076.1 - 2.4e-10 39.2 0.0 5.5e-06 25.5 0.0 3.3 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 ORY41076.1 - 3.5e-10 39.0 0.0 6.3e-05 22.6 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 ORY41076.1 - 2.5e-08 34.2 0.1 8e-05 23.0 0.0 3.4 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 ORY41076.1 - 2.5e-05 23.6 0.7 0.0028 17.1 0.0 2.7 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 ORY41076.1 - 0.00011 22.0 0.0 0.019 14.8 0.0 2.8 3 1 0 3 3 3 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 ORY41076.1 - 0.097 13.0 0.0 0.25 11.7 0.0 1.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2828 PF11443.8 ORY41077.1 - 4e-105 352.3 0.5 7.8e-90 301.8 0.3 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF2828) VWA_CoxE PF05762.14 ORY41077.1 - 0.0002 20.8 0.1 0.00036 20.0 0.1 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_2 PF13519.6 ORY41077.1 - 0.00026 21.6 0.0 0.00065 20.3 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF963 PF06131.11 ORY41077.1 - 0.046 13.1 0.8 0.11 12.0 0.8 1.6 1 0 0 1 1 1 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) DeoC PF01791.9 ORY41078.1 - 7.6e-10 38.8 0.6 9e-10 38.6 0.6 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase Methyltr_RsmB-F PF01189.17 ORY41079.1 - 2.5e-26 92.6 0.0 3.5e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 ORY41079.1 - 1.1e-05 25.6 0.0 2.7e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 ORY41079.1 - 0.056 13.2 0.0 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) zinc_ribbon_10 PF10058.9 ORY41080.1 - 3.6e-19 68.2 0.1 5.8e-19 67.6 0.1 1.3 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Lipase_3 PF01764.25 ORY41082.1 - 1.5e-34 118.9 0.0 1.9e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 ORY41082.1 - 0.0019 17.8 0.0 0.069 12.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 ORY41082.1 - 0.014 14.6 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Cutinase PF01083.22 ORY41082.1 - 0.019 14.9 0.1 0.026 14.5 0.1 1.4 1 1 0 1 1 1 0 Cutinase Abhydrolase_6 PF12697.7 ORY41082.1 - 0.031 14.9 0.0 0.037 14.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family zf-MYND PF01753.18 ORY41083.1 - 7.8e-05 22.7 13.7 0.00015 21.8 13.7 1.5 1 0 0 1 1 1 1 MYND finger Carboxyl_trans PF01039.22 ORY41084.1 - 8.2e-61 206.1 0.0 1.7e-60 205.1 0.0 1.5 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 ORY41084.1 - 5.2e-53 179.7 0.0 1.1e-52 178.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 ORY41084.1 - 2.7e-19 69.3 0.0 7.4e-19 67.8 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 ORY41084.1 - 5e-17 62.4 0.4 1e-10 42.1 0.0 2.7 1 1 1 2 2 2 2 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 ORY41084.1 - 1.9e-11 43.6 0.4 5.2e-11 42.2 0.4 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 ORY41084.1 - 2.2e-06 27.4 0.2 2.8e-05 23.8 0.1 2.5 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 ORY41084.1 - 1.6e-05 25.6 0.2 0.021 15.5 0.0 2.7 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp PF02222.22 ORY41084.1 - 0.00092 18.8 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.6 ORY41084.1 - 0.0041 17.1 0.1 0.015 15.3 0.1 1.9 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Dala_Dala_lig_C PF07478.13 ORY41084.1 - 0.0044 16.6 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_ST PF14397.6 ORY41084.1 - 0.0074 15.6 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp HlyD_D23 PF16576.5 ORY41084.1 - 0.018 14.3 0.1 1.5 8.0 0.0 2.3 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion ECH_1 PF00378.20 ORY41084.1 - 0.019 14.3 0.2 0.04 13.2 0.2 1.5 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase ATP-grasp_3 PF02655.14 ORY41084.1 - 0.12 12.4 0.1 2.7 8.0 0.1 2.8 1 1 0 1 1 1 0 ATP-grasp domain PS_Dcarbxylase PF02666.15 ORY41084.1 - 0.13 11.8 0.0 0.53 9.8 0.0 1.8 2 0 0 2 2 2 0 Phosphatidylserine decarboxylase DUF2118 PF09891.9 ORY41084.1 - 0.18 11.7 0.0 1.5 8.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) MadL PF03817.13 ORY41087.1 - 0.059 13.4 0.0 0.059 13.4 0.0 2.3 3 1 1 4 4 4 0 Malonate transporter MadL subunit SAM_1 PF00536.30 ORY41087.1 - 0.086 13.3 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Putative_PNPOx PF01243.20 ORY41088.1 - 5.2e-06 26.6 0.0 8.4e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF1729 PF08354.10 ORY41089.1 - 7.2e-147 488.9 0.0 1.2e-146 488.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) FAS_I_H PF18314.1 ORY41089.1 - 2.9e-69 232.8 0.5 9.6e-68 227.8 0.3 2.4 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain Acyl_transf_1 PF00698.21 ORY41089.1 - 2.2e-67 227.9 0.0 4.9e-67 226.7 0.0 1.7 1 0 0 1 1 1 1 Acyl transferase domain Fas_alpha_ACP PF18325.1 ORY41089.1 - 3.6e-60 203.0 0.0 6.5e-60 202.2 0.0 1.4 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_meander PF17951.1 ORY41089.1 - 1.4e-37 128.8 0.0 4.6e-37 127.1 0.0 2.0 2 0 0 2 2 2 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 ORY41089.1 - 2.8e-31 109.1 0.1 9.4e-31 107.4 0.0 2.0 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 ORY41089.1 - 3.5e-24 84.7 0.1 1.3e-23 82.8 0.1 2.0 1 0 0 1 1 1 1 MaoC like domain ketoacyl-synt PF00109.26 ORY41089.1 - 6.5e-20 71.8 0.0 3.4e-19 69.4 0.1 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 ORY41089.1 - 4.7e-14 52.5 0.0 1.3e-13 51.1 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 ORY41089.1 - 1.3e-13 51.0 0.0 4.5e-13 49.3 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain MaoC_dehydrat_N PF13452.6 ORY41089.1 - 2.2e-12 47.3 0.0 7.3e-12 45.6 0.0 1.9 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase FAS_N PF17828.1 ORY41089.1 - 1.1e-05 25.5 0.0 0.00077 19.5 0.0 2.5 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta An_peroxidase PF03098.15 ORY41090.1 - 1.1e-46 159.6 0.4 2.3e-42 145.3 0.2 2.2 1 1 1 2 2 2 2 Animal haem peroxidase ORC6 PF05460.13 ORY41090.1 - 0.2 10.9 1.5 0.56 9.4 1.1 1.9 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) TF_Otx PF03529.13 ORY41090.1 - 2.7 8.5 7.0 0.34 11.3 2.0 2.1 2 0 0 2 2 2 0 Otx1 transcription factor Atx10homo_assoc PF09759.9 ORY41091.1 - 2.7e-31 107.5 0.2 5.3e-30 103.4 0.0 2.8 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 ORY41091.1 - 0.16 11.4 0.1 1.4 8.3 0.0 2.2 2 1 1 3 3 3 0 Armadillo-like COPIIcoated_ERV PF07970.12 ORY41092.1 - 7.9e-88 294.0 0.3 9.8e-88 293.7 0.3 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 ORY41092.1 - 3.9e-12 46.4 0.2 8.2e-12 45.3 0.2 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase PF00069.25 ORY41093.1 - 6.9e-61 205.9 0.0 8.6e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY41093.1 - 6.1e-46 156.8 0.0 9.5e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY41093.1 - 2.6e-07 30.3 0.0 1.9e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like SUD-M PF11633.8 ORY41093.1 - 0.00036 20.2 0.0 0.0013 18.4 0.0 1.9 2 0 0 2 2 2 1 Single-stranded poly(A) binding domain Pkinase_fungal PF17667.1 ORY41093.1 - 0.0043 15.9 0.1 0.0053 15.6 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORY41093.1 - 0.026 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY41093.1 - 0.03 13.3 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain C2 PF00168.30 ORY41094.1 - 7.8e-16 58.2 0.0 2.8e-15 56.5 0.0 2.0 2 0 0 2 2 2 1 C2 domain RasGAP PF00616.19 ORY41094.1 - 2.6e-14 53.4 2.5 1.1e-13 51.4 0.0 2.9 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase FCH PF00611.23 ORY41094.1 - 2.5e-08 34.1 0.2 1e-07 32.1 0.2 2.1 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain PH PF00169.29 ORY41094.1 - 4.4e-07 30.4 0.1 9e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 PH domain FlaF PF07309.11 ORY41094.1 - 0.22 11.5 1.5 1.9 8.5 0.1 3.1 3 0 0 3 3 3 0 Flagellar protein FlaF cNMP_binding PF00027.29 ORY41095.1 - 2e-13 50.2 0.0 5.3e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 ORY41095.1 - 1.9e-12 47.0 3.2 1.9e-12 47.0 3.2 2.1 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 ORY41095.1 - 2.8e-10 39.8 12.4 9.5e-10 38.1 0.2 2.2 2 0 0 2 2 2 2 Ion transport protein DUF1764 PF08576.10 ORY41096.1 - 4.6e-19 69.2 12.1 1.4e-17 64.4 2.8 2.2 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF1764) Dicty_REP PF05086.12 ORY41096.1 - 0.7 7.8 6.1 0.74 7.7 6.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-C2H2_4 PF13894.6 ORY41097.1 - 6.3 7.9 5.9 0.92 10.5 0.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger PH PF00169.29 ORY41099.1 - 0.078 13.5 0.1 0.48 11.0 0.1 2.3 1 1 0 1 1 1 0 PH domain Amidohydro_1 PF01979.20 ORY41101.1 - 2.4e-08 33.7 0.2 8e-07 28.7 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 ORY41101.1 - 1.1e-07 31.7 0.6 3.5e-07 30.1 0.1 2.0 2 0 0 2 2 2 1 Amidohydrolase family UPF0515 PF15135.6 ORY41103.1 - 0.0018 17.7 2.4 0.0029 17.0 2.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein UPF0515 CH PF00307.31 ORY41104.1 - 1.2e-09 38.3 0.2 3.4e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 Calponin homology (CH) domain TrmO_C PF18389.1 ORY41105.1 - 0.091 12.9 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 TrmO C-terminal domain DUF4081 PF13312.6 ORY41106.1 - 0.19 12.0 0.1 1 9.6 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4081) TauD PF02668.16 ORY41193.1 - 1.8e-35 123.0 5.3 2.6e-27 96.3 0.1 2.4 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family Carboxyl_trans PF01039.22 ORY41194.1 - 1.8e-114 383.2 0.0 2.7e-92 310.0 0.0 2.2 2 0 0 2 2 2 2 Carboxyl transferase domain Hexokinase_1 PF00349.21 ORY41195.1 - 0.22 11.4 0.0 1.1 9.2 0.0 1.8 2 0 0 2 2 2 0 Hexokinase CS PF04969.16 ORY41196.1 - 4.4e-13 50.0 0.2 8.1e-13 49.2 0.2 1.5 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 ORY41196.1 - 1.5e-09 37.3 0.0 0.0014 18.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY41196.1 - 4.9e-09 35.6 1.6 0.0025 17.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY41196.1 - 9.3e-09 35.5 2.7 0.00087 19.5 5.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY41196.1 - 4.4e-07 30.4 5.3 1.7e-05 25.4 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY41196.1 - 1.1e-06 28.4 0.1 0.31 11.4 0.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat SGS PF05002.15 ORY41196.1 - 2.1e-06 27.7 0.2 4.6e-06 26.6 0.2 1.5 1 0 0 1 1 1 1 SGS domain TPR_19 PF14559.6 ORY41196.1 - 0.00054 20.4 0.8 0.14 12.7 0.0 2.6 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORY41196.1 - 0.0024 17.7 0.7 4.4 7.3 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY41196.1 - 0.0031 18.2 2.2 0.83 10.6 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY41196.1 - 0.0059 16.6 0.1 0.07 13.2 0.0 2.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.14 ORY41196.1 - 0.075 13.7 3.7 58 4.7 4.1 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY41196.1 - 0.081 12.6 0.0 2.1 8.1 0.0 2.5 2 0 0 2 2 2 0 TPR repeat Carbpep_Y_N PF05388.11 ORY41196.1 - 0.2 12.2 1.2 8.1 7.0 0.6 2.3 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide TPR_6 PF13174.6 ORY41196.1 - 0.24 12.1 3.7 25 5.8 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat PCRF PF03462.18 ORY41197.1 - 0.078 12.8 0.5 0.17 11.7 0.5 1.5 1 0 0 1 1 1 0 PCRF domain ATG16 PF08614.11 ORY41197.1 - 8.8 6.5 20.1 0.024 14.9 2.0 2.8 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Glyco_transf_4 PF13439.6 ORY41199.1 - 0.0048 16.9 0.0 0.0056 16.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 ORY41199.1 - 0.018 15.5 0.0 0.022 15.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 ORY41199.1 - 0.1 12.3 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 ORY41200.1 - 2.9e-24 86.0 0.1 4.9e-24 85.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 ORY41200.1 - 6.3e-23 81.2 0.0 5.1e-14 52.2 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 ORY41200.1 - 0.11 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Mersacidin PF16934.5 ORY41201.1 - 0.16 11.7 1.4 3.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Two-component Enterococcus faecalis cytolysin (EFC) Sel1 PF08238.12 ORY41202.1 - 5.9e-25 87.1 1.0 0.00013 22.5 0.0 5.4 5 0 0 5 5 5 5 Sel1 repeat TPR_6 PF13174.6 ORY41202.1 - 1.2e-07 31.9 0.7 0.21 12.3 0.1 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY41202.1 - 0.094 13.2 8.2 0.61 10.6 0.2 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat UvrD_C_2 PF13538.6 ORY41203.1 - 1.6e-09 37.5 0.0 0.0002 21.1 0.0 2.2 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 ORY41203.1 - 6.6e-08 32.3 0.0 1.1e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_12 PF13087.6 ORY41203.1 - 0.068 12.8 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ORY41204.1 - 0.017 15.4 0.0 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORY41204.1 - 0.14 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region WD40 PF00400.32 ORY41209.1 - 0.00057 20.6 0.5 3.3 8.7 0.1 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat tRNA-synt_1b PF00579.25 ORY41210.1 - 7.1e-67 225.8 0.0 3.1e-33 115.4 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) PfkB PF00294.24 ORY41211.1 - 9.4e-18 64.5 0.0 3.6e-11 42.9 0.0 2.5 3 0 0 3 3 3 2 pfkB family carbohydrate kinase Mucin15 PF15672.5 ORY41211.1 - 0.0049 16.4 1.8 0.008 15.7 1.8 1.3 1 0 0 1 1 1 1 Cell-membrane associated Mucin15 Se-cys_synth_N PF12390.8 ORY41211.1 - 0.22 11.8 2.0 0.27 11.5 0.1 2.1 2 0 0 2 2 2 0 Selenocysteine synthase N terminal Pkinase PF00069.25 ORY41212.1 - 2.7e-23 82.7 0.0 4.5e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY41212.1 - 2.9e-09 36.6 0.0 5e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY41212.1 - 1.6e-05 23.9 3.9 1.6e-05 23.9 3.9 2.3 2 1 0 2 2 2 1 Fungal protein kinase PDEase_I PF00233.19 ORY41214.1 - 7.8e-65 218.9 0.5 8.6e-65 218.8 0.5 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase ANF_receptor PF01094.28 ORY41215.1 - 3.4e-11 42.8 1.1 4.8e-11 42.4 1.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY41215.1 - 0.00076 19.2 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein BtpA PF03437.15 ORY41215.1 - 0.082 12.3 0.1 2.4 7.5 0.0 2.5 2 1 0 2 2 2 0 BtpA family F-box-like PF12937.7 ORY41216.1 - 1e-13 51.0 0.9 1.7e-13 50.2 0.9 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY41216.1 - 0.0013 18.5 1.2 0.0037 17.1 1.2 1.8 1 1 0 1 1 1 1 F-box domain Armet PF10208.9 ORY41216.1 - 0.024 14.6 0.2 0.042 13.8 0.0 1.5 2 0 0 2 2 2 0 Degradation arginine-rich protein for mis-folding Fib_alpha PF08702.10 ORY41217.1 - 0.21 11.8 1.8 0.41 10.8 1.8 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family EamA PF00892.20 ORY41218.1 - 2.2e-26 92.7 29.3 3.8e-19 69.2 15.2 2.5 2 1 0 2 2 2 2 EamA-like transporter family BaxI_1 PF12811.7 ORY41218.1 - 0.68 9.5 14.7 0.79 9.2 11.5 2.5 1 1 1 2 2 2 0 Bax inhibitor 1 like DUF2070 PF09843.9 ORY41218.1 - 7.2 4.8 16.4 1.6 6.9 9.5 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Glyco_hydro_20 PF00728.22 ORY41219.1 - 5.3e-75 253.0 0.0 1e-74 252.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain ECH_1 PF00378.20 ORY41219.1 - 1.2e-43 149.2 0.0 3.1e-39 134.8 0.0 2.3 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY41219.1 - 5.4e-22 78.7 0.0 4e-19 69.3 0.0 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Glyco_hydro_20b PF02838.15 ORY41219.1 - 6.5e-10 39.8 0.0 1.2e-09 39.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 ORY41219.1 - 1.7e-07 32.0 0.1 3.3e-06 27.8 0.1 2.7 2 1 0 2 2 2 1 beta-acetyl hexosaminidase like DUF3767 PF12597.8 ORY41220.1 - 0.14 12.0 0.3 0.21 11.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) Usp PF00582.26 ORY41224.1 - 0.075 13.5 0.0 0.16 12.5 0.0 1.5 1 0 0 1 1 1 0 Universal stress protein family Methyltransf_31 PF13847.6 ORY41226.1 - 0.00071 19.4 0.0 0.00087 19.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY41226.1 - 0.0068 17.1 0.0 0.0092 16.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CPSase_L_D2 PF02786.17 ORY41227.1 - 3e-70 236.0 0.0 5.3e-70 235.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ORY41227.1 - 1.1e-45 154.6 0.2 2.6e-45 153.5 0.2 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORY41227.1 - 3e-29 101.3 0.0 7.8e-29 99.9 0.0 1.8 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ORY41227.1 - 3e-11 43.0 3.5 8.6e-11 41.5 3.5 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ORY41227.1 - 6.1e-10 39.0 0.0 1.6e-09 37.6 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 ORY41227.1 - 1.6e-09 37.6 0.0 6.7e-09 35.5 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 ORY41227.1 - 5.7e-07 29.3 0.1 0.011 15.5 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 ORY41227.1 - 1.1e-06 28.8 0.0 1.9e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 ORY41227.1 - 0.0003 20.5 0.0 0.0017 18.0 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.6 ORY41227.1 - 0.0042 17.8 2.8 1.3 9.7 0.2 4.2 4 1 1 5 5 5 2 HlyD family secretion protein PDZ_2 PF13180.6 ORY41227.1 - 0.16 12.3 0.6 19 5.7 0.1 2.8 2 0 0 2 2 2 0 PDZ domain Ion_trans PF00520.31 ORY41228.1 - 5.8e-13 48.6 9.1 1.3e-12 47.4 9.1 1.5 1 1 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 ORY41228.1 - 6.3e-12 45.4 0.0 1.5e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 ORY41228.1 - 7.4e-11 41.9 6.3 7.4e-11 41.9 6.3 1.9 2 0 0 2 2 2 1 Ion channel DUF2514 PF10721.9 ORY41228.1 - 0.22 11.6 1.9 0.45 10.5 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Rap1-DNA-bind PF09197.10 ORY41228.1 - 0.28 11.8 3.5 0.2 12.3 0.8 2.1 2 0 0 2 2 2 0 Rap1, DNA-binding TPH PF13868.6 ORY41229.1 - 4.2e-19 68.3 85.4 4.2e-19 68.3 85.4 1.9 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain Bap31 PF05529.12 ORY41229.1 - 0.85 9.5 5.8 0.87 9.4 1.8 2.6 2 0 0 2 2 2 0 Bap31/Bap29 transmembrane region DUF4302 PF14135.6 ORY41229.1 - 1.8 8.4 7.2 1.1 9.2 0.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4302) Peptidase_M16_C PF05193.21 ORY41230.1 - 1.7e-19 70.6 0.0 3.2e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ORY41230.1 - 1.1e-11 44.9 0.0 2.4e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) HTH_15 PF12324.8 ORY41230.1 - 0.0091 15.9 1.7 0.081 12.9 0.2 2.8 1 1 1 2 2 2 1 Helix-turn-helix domain of alkylmercury lyase DUF438 PF04282.13 ORY41230.1 - 0.12 12.3 0.1 0.7 9.9 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF438) Phosducin PF02114.16 ORY41232.1 - 5.7e-07 28.7 1.7 7.5e-07 28.4 1.7 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 ORY41232.1 - 1.7e-05 24.7 0.1 4e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Glyco_hydro_31 PF01055.26 ORY41233.1 - 7.8e-104 348.3 0.0 9.8e-104 348.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 ORY41233.1 - 0.0049 17.2 0.1 0.014 15.7 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4968) DUF5110 PF17137.4 ORY41233.1 - 0.014 15.6 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) MoaF PF10703.9 ORY41233.1 - 0.028 14.4 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 MoaF N-terminal domain zf-BED PF02892.15 ORY41234.1 - 0.00017 21.6 1.7 0.0003 20.7 1.7 1.4 1 0 0 1 1 1 1 BED zinc finger zf-C2H2_4 PF13894.6 ORY41234.1 - 0.00029 21.4 1.0 0.0014 19.2 1.0 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY41234.1 - 0.013 15.9 1.5 0.013 15.9 1.5 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type Paired_CXXCH_1 PF09699.10 ORY41234.1 - 0.028 14.2 0.2 0.06 13.1 0.2 1.5 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) zf-C2H2_2 PF12756.7 ORY41234.1 - 0.052 13.9 0.2 0.084 13.2 0.2 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Arv1 PF04161.13 ORY41236.1 - 1e-51 176.1 13.5 1.2e-51 175.9 13.5 1.1 1 0 0 1 1 1 1 Arv1-like family PRKCSH PF07915.13 ORY41237.1 - 7.8e-11 42.8 0.6 2.5e-10 41.2 0.6 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 ORY41237.1 - 6.5e-07 29.1 2.6 2.7e-06 27.1 2.6 2.0 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF2002 PF09400.10 ORY41237.1 - 0.086 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2002) AAA PF00004.29 ORY41238.1 - 6.1e-30 104.3 0.0 2e-29 102.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY41238.1 - 2.7e-13 49.5 0.2 2.7e-13 49.5 0.2 2.5 3 0 0 3 3 3 1 AAA+ lid domain Vps4_C PF09336.10 ORY41238.1 - 1.4e-09 37.8 0.0 4.6e-09 36.1 0.0 1.9 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 ORY41238.1 - 7.8e-06 25.7 0.0 3e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 ORY41238.1 - 0.00032 20.9 0.0 0.00067 19.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY41238.1 - 0.00043 20.6 0.6 0.0072 16.6 0.3 2.5 2 1 1 3 3 2 1 AAA domain TIP49 PF06068.13 ORY41238.1 - 0.0011 18.2 0.0 0.0032 16.8 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_2 PF07724.14 ORY41238.1 - 0.0018 18.4 0.0 0.0037 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 ORY41238.1 - 0.003 17.3 0.0 0.0055 16.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 ORY41238.1 - 0.0045 17.0 0.1 0.014 15.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 ORY41238.1 - 0.0056 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 ORY41238.1 - 0.0094 16.5 0.8 0.054 14.0 0.6 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY41238.1 - 0.011 16.1 0.0 0.028 14.8 0.0 1.7 2 0 0 2 2 1 0 AAA ATPase domain AAA_24 PF13479.6 ORY41238.1 - 0.033 13.9 0.0 0.092 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY41238.1 - 0.036 14.5 0.0 0.16 12.3 0.0 2.2 2 0 0 2 2 2 0 RNA helicase AAA_14 PF13173.6 ORY41238.1 - 0.04 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 ORY41238.1 - 0.045 13.1 2.0 0.84 8.9 0.1 2.8 2 1 1 3 3 3 0 KaiC AAA_7 PF12775.7 ORY41238.1 - 0.054 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 ORY41238.1 - 0.062 12.8 0.1 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 ORY41238.1 - 0.17 12.1 0.1 0.34 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain MHCassoc_trimer PF08831.10 ORY41238.1 - 0.19 11.8 1.5 0.77 9.8 0.1 2.6 3 0 0 3 3 2 0 Class II MHC-associated invariant chain trimerisation domain Aldo_ket_red PF00248.21 ORY41240.1 - 2.5e-29 102.4 0.2 7.9e-26 90.9 0.2 3.0 1 1 0 1 1 1 1 Aldo/keto reductase family PBP_like_2 PF12849.7 ORY41241.1 - 9.5e-23 81.3 0.0 2.3e-22 80.0 0.0 1.5 1 1 0 1 1 1 1 PBP superfamily domain DUF2070 PF09843.9 ORY41242.1 - 0.00081 17.8 6.0 0.001 17.5 6.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) DUF3810 PF12725.7 ORY41242.1 - 0.0045 16.4 0.1 0.0045 16.4 0.1 2.3 1 1 1 2 2 2 1 Protein of unknown function (DUF3810) DUF2339 PF10101.9 ORY41242.1 - 0.01 14.5 4.0 0.019 13.6 4.0 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2339) ExoD PF06055.12 ORY41242.1 - 0.023 14.1 0.2 0.058 12.8 0.2 1.6 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD DUF1772 PF08592.11 ORY41242.1 - 0.039 14.3 1.6 4 7.8 0.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) 7tm_1 PF00001.21 ORY41242.1 - 1.5 8.1 8.4 13 5.1 8.4 2.1 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF4079 PF13301.6 ORY41242.1 - 6.2 7.0 7.5 57 3.8 7.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) DUF3611 PF12263.8 ORY41242.1 - 6.3 6.7 10.6 1.3 8.8 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) EF-hand_7 PF13499.6 ORY41243.1 - 3.2e-08 33.9 0.2 4.1e-08 33.5 0.2 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF_assoc_1 PF08355.12 ORY41243.1 - 1.2e-05 24.8 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 EF hand associated EF-hand_6 PF13405.6 ORY41243.1 - 3.3e-05 23.5 0.4 0.0023 17.7 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 ORY41243.1 - 0.0019 17.6 0.1 0.0049 16.3 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 ORY41243.1 - 0.0059 16.0 0.9 0.0059 16.0 0.9 1.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 ORY41243.1 - 0.24 11.3 2.5 3.8 7.4 0.7 2.2 1 1 2 3 3 3 0 EF-hand domain pair Med9 PF07544.13 ORY41244.1 - 0.05 13.7 0.4 0.12 12.4 0.4 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 PhzC-PhzF PF02567.16 ORY41245.1 - 1.4e-30 106.8 0.0 1.5e-30 106.6 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Mannosyl_trans3 PF11051.8 ORY41247.1 - 3.2e-33 115.3 0.0 2e-32 112.6 0.0 1.9 1 1 0 1 1 1 1 Mannosyltransferase putative WW PF00397.26 ORY41247.1 - 0.099 12.8 1.2 6.6 6.9 0.5 2.6 2 0 0 2 2 2 0 WW domain TPR_19 PF14559.6 ORY41248.1 - 1.9e-07 31.5 1.6 8.4e-05 23.0 0.7 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY41248.1 - 0.0012 18.8 0.1 8.5 6.8 0.5 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY41248.1 - 0.0015 17.9 0.7 0.015 14.7 0.7 2.1 1 1 0 1 1 1 1 MalT-like TPR region TPR_12 PF13424.6 ORY41248.1 - 0.0033 17.7 2.9 4.3 7.7 0.4 3.9 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY41248.1 - 0.043 14.5 0.9 0.18 12.5 0.7 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Sec16_C PF12931.7 ORY41248.1 - 0.084 12.5 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 ANAPC3 PF12895.7 ORY41248.1 - 0.12 12.6 0.4 0.53 10.6 0.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 ORY41248.1 - 0.13 12.0 0.6 0.23 11.1 0.6 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain OPT PF03169.15 ORY41249.1 - 2.5e-124 416.2 45.8 3.2e-124 415.9 45.8 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.8 ORY41249.1 - 2.3 8.5 5.7 9 6.5 5.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) zf-UBP PF02148.19 ORY41250.1 - 7.1e-13 48.7 6.7 1.5e-12 47.7 6.7 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein DUSP PF06337.12 ORY41250.1 - 9.9e-09 35.7 0.0 4.4e-08 33.6 0.0 2.1 2 1 0 2 2 2 1 DUSP domain F-box-like PF12937.7 ORY41250.1 - 0.0015 18.4 0.1 0.0015 18.4 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY41250.1 - 0.034 14.1 0.1 0.11 12.4 0.1 1.8 1 0 0 1 1 1 0 F-box domain DUF1473 PF07341.11 ORY41251.1 - 0.013 15.3 1.0 0.023 14.4 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1473) zf-C2H2_3 PF13878.6 ORY41251.1 - 0.16 11.8 1.6 0.34 10.8 0.1 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO RINGv PF12906.7 ORY41251.1 - 0.69 10.1 4.4 15 5.8 4.4 2.5 1 1 0 1 1 1 0 RING-variant domain RhoGAP PF00620.27 ORY41253.1 - 7.9e-30 103.7 0.0 1.3e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Complex1_LYR PF05347.15 ORY41254.1 - 0.0014 18.6 1.9 0.083 12.9 1.9 2.2 1 1 0 1 1 1 1 Complex 1 protein (LYR family) TFIIA PF03153.13 ORY41255.1 - 0.07 13.1 12.8 0.09 12.8 12.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 ORY41255.1 - 3.7 6.1 27.4 5.1 5.7 27.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RNase_T PF00929.24 ORY41256.1 - 2.2e-07 31.6 0.0 2.9e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 ORY41256.1 - 0.0052 16.5 0.0 0.0057 16.4 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease LRR_4 PF12799.7 ORY41257.1 - 4.2e-15 55.6 11.6 0.00018 21.8 0.1 4.8 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY41257.1 - 5e-15 55.0 13.8 4.1e-08 32.9 3.6 4.0 3 1 2 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 ORY41257.1 - 3e-12 45.3 17.4 0.059 13.9 0.2 7.3 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_6 PF13516.6 ORY41257.1 - 0.0021 18.0 19.7 5.4 7.3 0.4 6.1 7 0 0 7 7 7 3 Leucine Rich repeat F-box PF00646.33 ORY41257.1 - 0.0044 16.9 1.1 0.015 15.2 1.1 1.9 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.6 ORY41258.1 - 2.2e-13 49.8 14.7 5.1e-10 39.0 0.3 4.0 4 1 1 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 ORY41258.1 - 8.9e-13 48.2 19.6 2.1e-08 34.3 0.8 5.1 3 1 4 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY41258.1 - 0.00015 21.9 16.6 1.6 9.6 0.7 7.1 5 1 1 6 6 6 2 Leucine Rich Repeat F-box PF00646.33 ORY41258.1 - 0.00017 21.4 0.5 0.00082 19.2 0.5 2.2 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY41258.1 - 0.015 15.2 0.6 0.015 15.2 0.6 2.7 3 0 0 3 3 3 0 F-box-like LRR_9 PF14580.6 ORY41258.1 - 0.13 11.8 1.2 0.45 10.0 0.1 2.0 1 1 2 3 3 3 0 Leucine-rich repeat FNIP PF05725.12 ORY41258.1 - 0.19 11.9 2.6 22 5.3 0.1 3.5 2 1 0 2 2 2 0 FNIP Repeat LRR_6 PF13516.6 ORY41258.1 - 5.1 7.4 19.0 8.4 6.7 0.1 5.8 6 0 0 6 6 6 0 Leucine Rich repeat LRR_8 PF13855.6 ORY41259.1 - 1e-18 66.8 22.1 1.2e-08 34.6 2.1 3.5 3 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY41259.1 - 2.3e-16 59.6 27.7 7.8e-05 23.0 8.4 5.0 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY41259.1 - 3.7e-08 32.8 26.2 0.032 14.7 0.4 7.0 6 2 0 6 6 6 3 Leucine Rich Repeat FNIP PF05725.12 ORY41259.1 - 0.49 10.6 11.0 6.1 7.1 0.1 4.9 3 1 1 4 4 4 0 FNIP Repeat LRR_6 PF13516.6 ORY41259.1 - 2.1 8.6 19.0 4 7.7 0.1 5.4 5 0 0 5 5 5 0 Leucine Rich repeat LRR_9 PF14580.6 ORY41259.1 - 4.4 6.8 8.7 4.4 6.8 1.3 2.9 1 1 2 3 3 3 0 Leucine-rich repeat Mito_carr PF00153.27 ORY41260.1 - 3.6e-27 94.1 6.4 1.2e-12 47.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 ORY41261.1 - 2.2e-09 36.7 29.9 2.2e-09 36.7 29.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 ORY41261.1 - 0.05 13.3 0.0 0.05 13.3 0.0 4.1 4 3 0 4 4 4 0 Ion channel regulatory protein UNC-93 ETF PF01012.21 ORY41262.1 - 4.1e-45 153.9 3.4 8e-45 153.0 3.4 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Ion_trans_2 PF07885.16 ORY41263.1 - 1.2e-07 31.6 7.4 1.2e-07 31.6 7.4 3.3 4 0 0 4 4 4 1 Ion channel Flu_M2 PF00599.17 ORY41263.1 - 0.022 14.8 2.8 0.58 10.3 0.0 2.8 3 0 0 3 3 3 0 Influenza Matrix protein (M2) Ion_trans_2 PF07885.16 ORY41264.1 - 5.5e-13 48.7 23.2 2.2e-07 30.8 9.0 2.6 2 0 0 2 2 2 2 Ion channel DUF1772 PF08592.11 ORY41264.1 - 0.028 14.7 1.5 0.028 14.7 1.5 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) Snapin_Pallidin PF14712.6 ORY41265.1 - 4.1e-12 46.4 0.3 4.5e-12 46.2 0.3 1.0 1 0 0 1 1 1 1 Snapin/Pallidin Nitr_red_bet_C PF14711.6 ORY41265.1 - 0.071 12.8 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal Vmethyltransf_C PF08456.10 ORY41266.1 - 0.018 14.6 0.7 0.025 14.1 0.7 1.2 1 0 0 1 1 1 0 Viral methyltransferase C-terminal FAM199X PF15814.5 ORY41266.1 - 0.74 8.8 8.0 1.1 8.2 8.0 1.2 1 0 0 1 1 1 0 Protein family FAM199X Neuropeptide_S PF14993.6 ORY41267.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Neuropeptide S precursor protein ALS2CR11 PF15729.5 ORY41268.1 - 0.00022 20.5 0.0 0.00023 20.4 0.0 1.1 1 0 0 1 1 1 1 Amyotrophic lateral sclerosis 2 candidate 11 C2 PF00168.30 ORY41268.1 - 0.0013 19.0 0.0 0.0027 18.0 0.0 1.5 2 0 0 2 2 2 1 C2 domain LRR_9 PF14580.6 ORY41269.1 - 1e-09 38.1 2.4 1e-09 38.1 2.4 2.1 2 0 0 2 2 2 1 Leucine-rich repeat Uteroglobin PF01099.17 ORY41269.1 - 0.03 14.6 4.1 0.29 11.5 0.7 3.0 1 1 1 2 2 2 0 Uteroglobin family Pet191_N PF10203.9 ORY41269.1 - 0.041 14.2 0.5 0.1 12.9 0.5 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 PKK PF12474.8 ORY41269.1 - 0.051 13.7 4.4 0.099 12.8 3.6 1.9 1 1 0 1 1 1 0 Polo kinase kinase LRR_4 PF12799.7 ORY41269.1 - 0.051 14.0 14.4 0.3 11.6 7.1 3.8 2 2 0 2 2 2 0 Leucine Rich repeats (2 copies) Gp-FAR-1 PF05823.12 ORY41269.1 - 0.088 13.2 6.4 0.39 11.1 1.9 2.8 2 1 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Syntaxin_2 PF14523.6 ORY41269.1 - 0.13 12.7 5.3 0.19 12.1 1.6 3.0 2 1 0 2 2 2 0 Syntaxin-like protein PI_PP_I PF18363.1 ORY41269.1 - 0.26 11.5 1.5 0.95 9.7 0.2 2.5 2 1 1 3 3 3 0 Phosphoinositide phosphatase insertion domain DUF1664 PF07889.12 ORY41269.1 - 0.35 10.9 5.9 27 4.8 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF148 PF02520.17 ORY41269.1 - 0.46 10.6 9.0 0.15 12.2 1.2 3.5 2 1 2 4 4 4 0 Domain of unknown function DUF148 EF-G-binding_N PF07299.11 ORY41269.1 - 0.5 10.9 7.8 0.27 11.8 0.3 3.7 4 2 0 4 4 4 0 Elongation factor G-binding protein, N-terminal AATF-Che1 PF13339.6 ORY41269.1 - 1.3 9.7 5.5 11 6.7 5.5 2.7 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor ArdA PF07275.11 ORY41269.1 - 9.2 6.8 8.8 78 3.8 8.7 2.6 1 1 0 1 1 1 0 Antirestriction protein (ArdA) F-box-like PF12937.7 ORY41270.1 - 0.0005 19.9 0.4 0.0013 18.6 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY41270.1 - 0.026 14.4 0.1 0.062 13.2 0.0 1.7 2 0 0 2 2 2 0 F-box domain LRR_6 PF13516.6 ORY41271.1 - 4.7e-08 32.5 13.7 0.02 14.9 0.1 5.6 6 0 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 ORY41271.1 - 0.0002 21.6 1.3 0.024 15.1 0.5 2.8 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY41271.1 - 0.022 14.5 1.6 33 4.3 0.6 3.8 3 1 0 3 3 3 0 Leucine rich repeat Sec20 PF03908.13 ORY41272.1 - 0.0028 17.5 0.2 0.006 16.5 0.2 1.5 1 0 0 1 1 1 1 Sec20 HisKA_3 PF07730.13 ORY41273.1 - 0.058 13.9 0.4 0.065 13.8 0.4 1.1 1 0 0 1 1 1 0 Histidine kinase Rab_bind PF16704.5 ORY41273.1 - 0.059 13.4 0.1 0.088 12.9 0.0 1.4 1 1 0 1 1 1 0 Rab binding domain COG2 PF06148.11 ORY41273.1 - 0.062 13.4 0.1 0.066 13.3 0.1 1.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 SlyX PF04102.12 ORY41273.1 - 0.074 13.7 0.2 0.084 13.5 0.2 1.1 1 0 0 1 1 1 0 SlyX DUF836 PF05768.14 ORY41274.1 - 1.8e-15 57.1 0.1 2.5e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin PF00085.20 ORY41274.1 - 0.0032 17.4 0.0 0.0033 17.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 ORY41274.1 - 0.0054 16.9 0.0 0.039 14.2 0.0 2.4 3 0 0 3 3 3 1 Glutaredoxin TraF PF13728.6 ORY41274.1 - 0.035 13.9 0.0 0.043 13.6 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein REF PF05755.12 ORY41274.1 - 0.065 13.0 0.0 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) Methyltransf_22 PF13383.6 ORY41275.1 - 3.2e-15 56.4 0.1 4.1e-15 56.1 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 ORY41275.1 - 0.00023 21.2 0.0 0.0004 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_22 PF13383.6 ORY41277.1 - 1.2e-11 44.7 5.0 2.4e-11 43.7 5.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 ORY41277.1 - 0.0028 17.7 0.0 0.0052 16.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain ZF-HD_dimer PF04770.12 ORY41277.1 - 0.073 13.4 0.2 0.19 12.1 0.2 1.7 1 0 0 1 1 1 0 ZF-HD protein dimerisation region SNF2_N PF00176.23 ORY41278.1 - 2.3e-56 191.0 1.6 3.5e-55 187.1 1.1 2.9 1 1 1 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.15 ORY41278.1 - 0.00062 19.8 0.1 0.0048 16.9 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Eapp_C PF10238.9 ORY41278.1 - 0.66 10.1 6.5 0.56 10.3 1.7 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein LRR_8 PF13855.6 ORY41279.1 - 1.2e-23 82.6 14.4 1.3e-07 31.2 3.8 5.4 3 2 2 6 6 6 5 Leucine rich repeat LRR_1 PF00560.33 ORY41279.1 - 4.6e-21 72.1 13.5 0.0022 18.3 0.1 10.0 10 0 0 10 10 10 7 Leucine Rich Repeat LRR_4 PF12799.7 ORY41279.1 - 1.6e-19 69.7 12.4 1.2e-05 25.6 1.7 6.1 3 2 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY41279.1 - 1.2e-07 31.2 29.7 0.27 11.4 0.2 8.5 9 0 0 9 9 9 5 Leucine Rich repeat DUF5612 PF18462.1 ORY41279.1 - 0.0012 18.7 0.0 0.017 14.9 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF5612) F-box-like PF12937.7 ORY41279.1 - 0.002 18.0 0.7 0.0082 16.0 0.7 2.1 1 0 0 1 1 1 1 F-box-like SNF2_N PF00176.23 ORY41281.1 - 4.2e-58 196.7 1.0 6.2e-58 196.2 1.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY41281.1 - 4.2e-09 36.7 0.2 0.00014 22.1 0.0 3.0 2 1 1 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 ORY41281.1 - 1.2e-05 25.2 0.0 3.1e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ORY41281.1 - 3.4e-05 23.9 1.4 7.4e-05 22.8 0.0 2.3 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit zinc-ribbons_6 PF07191.12 ORY41281.1 - 0.024 14.6 0.1 0.051 13.6 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbons zf_Rg PF17915.1 ORY41281.1 - 0.12 11.8 0.1 0.98 8.9 0.0 2.3 2 0 0 2 2 2 0 Reverse gyrase zinc finger TFIIE-A_C PF11521.8 ORY41281.1 - 0.14 12.5 2.3 0.32 11.3 2.3 1.6 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha RRN3 PF05327.11 ORY41281.1 - 0.18 10.3 0.6 0.24 9.9 0.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC27 PF09507.10 ORY41281.1 - 1.3 8.3 5.4 2.2 7.6 5.4 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 UAA PF08449.11 ORY41283.1 - 0.00044 19.6 19.2 0.00073 18.8 19.2 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 ORY41283.1 - 0.0027 17.9 11.2 0.0027 17.9 11.2 2.3 2 0 0 2 2 2 1 EamA-like transporter family Cas_DxTHG PF09455.10 ORY41284.1 - 0.012 15.3 0.1 0.014 15.0 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family MoCF_biosynth PF00994.24 ORY41286.1 - 6.4e-31 107.0 0.3 1.3e-30 105.9 0.0 1.7 2 0 0 2 2 2 1 Probable molybdopterin binding domain FCH PF00611.23 ORY41287.1 - 7.1e-15 55.1 2.7 1e-14 54.6 0.5 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF724 PF05266.14 ORY41287.1 - 2.6 7.8 15.7 2 8.2 2.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF724) Syntaxin-6_N PF09177.11 ORY41287.1 - 2.8 8.6 15.4 0.13 12.9 1.0 3.9 4 1 0 4 4 4 0 Syntaxin 6, N-terminal Sel1 PF08238.12 ORY41288.1 - 6.1e-27 93.5 0.6 0.00064 20.3 0.0 6.9 7 0 0 7 7 7 6 Sel1 repeat Ribosomal_L24e PF01246.20 ORY41289.1 - 1.2e-31 108.7 6.0 1.2e-31 108.7 6.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e SPRY PF00622.28 ORY41290.1 - 4.5e-11 42.9 0.3 0.00039 20.5 0.0 2.4 2 0 0 2 2 2 2 SPRY domain PHD PF00628.29 ORY41290.1 - 0.0048 16.8 3.4 0.011 15.6 3.4 1.7 1 0 0 1 1 1 1 PHD-finger Zf_RING PF16744.5 ORY41290.1 - 0.022 14.9 1.5 0.045 13.9 0.6 1.9 2 0 0 2 2 2 0 KIAA1045 RING finger DNAPolymera_Pol PF11590.8 ORY41290.1 - 0.043 13.7 0.1 3 7.8 0.0 2.6 2 0 0 2 2 2 0 DNA polymerase catalytic subunit Pol C1_1 PF00130.22 ORY41290.1 - 0.075 12.9 1.4 0.22 11.5 1.4 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RINGv PF12906.7 ORY41290.1 - 0.078 13.1 1.6 0.19 11.9 1.6 1.6 1 0 0 1 1 1 0 RING-variant domain CMV_US PF08001.11 ORY41290.1 - 0.22 10.8 0.3 1.1 8.5 0.3 2.1 1 1 0 1 1 1 0 CMV US PH_17 PF18012.1 ORY41291.1 - 0.0031 17.2 0.2 0.0087 15.8 0.2 1.7 1 0 0 1 1 1 1 PH domain PH PF00169.29 ORY41291.1 - 0.0074 16.8 0.2 0.055 14.0 0.2 2.1 1 1 0 1 1 1 1 PH domain MoCF_biosynth PF00994.24 ORY41291.1 - 0.0091 15.7 0.2 0.016 14.9 0.2 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain PH_8 PF15409.6 ORY41291.1 - 0.014 15.7 0.5 0.043 14.1 0.1 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain PH_9 PF15410.6 ORY41291.1 - 0.03 14.7 0.1 0.087 13.2 0.1 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain Ctr PF04145.15 ORY41292.1 - 0.09 13.4 0.0 0.13 12.9 0.0 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Peptidase_M20 PF01546.28 ORY41293.1 - 7.1e-14 52.0 0.0 2.2e-13 50.4 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY41293.1 - 1.1e-08 34.9 0.0 2.4e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain RrnaAD PF00398.20 ORY41294.1 - 3.1e-28 98.6 1.6 2.7e-15 56.2 1.0 4.4 2 1 0 2 2 2 2 Ribosomal RNA adenine dimethylase Glyco_hydro_35 PF01301.19 ORY41295.1 - 2.9e-28 99.4 2.5 4.7e-28 98.7 2.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 GHD PF17834.1 ORY41295.1 - 0.00011 22.2 0.1 0.0037 17.3 0.0 2.8 2 0 0 2 2 2 1 Beta-sandwich domain in beta galactosidase RabGAP-TBC PF00566.18 ORY41297.1 - 2.6e-05 24.0 0.0 3.4e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 ORY41298.1 - 1.2e-06 27.9 1.9 1.2e-06 27.9 1.9 1.9 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 ORY41298.1 - 1e-05 24.7 1.7 1.5e-05 24.2 0.8 1.9 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 ORY41298.1 - 1.1e-05 25.8 0.1 2.7e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 ORY41298.1 - 0.00033 20.0 0.6 0.00078 18.8 0.6 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 ORY41298.1 - 0.00099 18.9 0.2 0.0023 17.7 0.2 1.6 1 0 0 1 1 1 1 EF-hand domain pair Drf_DAD PF06345.11 ORY41298.1 - 0.11 12.5 0.1 0.39 10.8 0.1 2.0 1 0 0 1 1 1 0 DRF Autoregulatory Domain APS_kinase PF01583.20 ORY41301.1 - 1.8e-71 239.1 0.0 2.3e-71 238.8 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 ORY41301.1 - 2.6e-08 34.1 0.0 5.1e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 ORY41301.1 - 0.0021 17.6 0.0 0.0025 17.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 ORY41301.1 - 0.0024 18.4 0.0 0.0037 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORY41301.1 - 0.0069 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ER_lumen_recept PF00810.18 ORY41302.1 - 5.1e-40 137.7 4.2 1.3e-37 129.9 0.4 2.3 2 0 0 2 2 2 2 ER lumen protein retaining receptor CxC4 PF18717.1 ORY41302.1 - 0.015 15.1 0.1 0.03 14.2 0.1 1.5 1 1 0 1 1 1 0 CxC4 like cysteine cluster associated with KDZ transposases DUF3430 PF11912.8 ORY41304.1 - 0.13 12.3 7.4 1 9.3 7.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3430) GST_N PF02798.20 ORY41306.1 - 1e-11 45.0 0.1 2.2e-11 43.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY41306.1 - 1.1e-09 38.4 0.0 2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY41306.1 - 3.2e-09 37.1 0.0 5.5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY41306.1 - 1.7e-08 34.6 0.0 4.4e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY41306.1 - 2.8e-06 27.4 0.0 6.4e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY41306.1 - 1.6e-05 24.8 0.0 4.1e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Amino_oxidase PF01593.24 ORY41308.1 - 1.8e-54 185.7 0.0 4.7e-54 184.4 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase VHS PF00790.19 ORY41309.1 - 1e-09 38.4 0.0 1.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 VHS domain GAT PF03127.14 ORY41309.1 - 0.00032 21.0 0.2 0.0014 18.9 0.0 2.1 2 0 0 2 2 2 1 GAT domain DUF150 PF02576.17 ORY41309.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 RimP N-terminal domain FAM75 PF14650.6 ORY41309.1 - 0.49 9.9 5.3 0.9 9.0 5.3 1.3 1 0 0 1 1 1 0 FAM75 family DUF2076 PF09849.9 ORY41309.1 - 1.3 9.0 4.4 0.26 11.3 0.8 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) VHS PF00790.19 ORY41312.1 - 0.00051 19.9 0.0 0.0007 19.5 0.0 1.2 1 0 0 1 1 1 1 VHS domain Acetyltransf_1 PF00583.25 ORY41313.1 - 5.8e-10 39.4 0.0 6.6e-09 36.0 0.1 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY41313.1 - 5.3e-07 30.0 0.1 4.6e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY41313.1 - 6e-07 29.5 0.0 2.2e-06 27.6 0.1 1.9 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY41313.1 - 1.8e-05 24.6 0.1 3.6e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 ORY41313.1 - 0.00016 21.7 0.0 0.00081 19.5 0.0 2.2 1 1 1 2 2 2 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 ORY41313.1 - 0.04 13.6 0.2 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ Prok-RING_4 PF14447.6 ORY41314.1 - 4.9e-09 35.9 5.6 8e-09 35.2 5.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 ORY41314.1 - 7e-09 35.4 7.0 1.1e-08 34.8 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY41314.1 - 9.3e-08 32.3 8.5 1.6e-07 31.6 8.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY41314.1 - 3.1e-07 30.1 8.4 5.3e-07 29.4 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY41314.1 - 4.3e-06 26.6 6.4 8.4e-06 25.7 6.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY41314.1 - 8e-06 25.6 8.2 1.4e-05 24.8 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY41314.1 - 2.7e-05 24.4 5.0 5.7e-05 23.3 5.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain Helicase_C PF00271.31 ORY41314.1 - 6.9e-05 23.2 0.0 0.00042 20.6 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 ORY41314.1 - 0.00037 20.4 3.0 0.00075 19.5 3.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 ORY41314.1 - 0.0082 16.3 6.5 0.0082 16.3 6.5 1.8 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 ORY41314.1 - 0.0088 15.8 6.0 0.019 14.7 6.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_9 PF18444.1 ORY41314.1 - 0.045 13.6 0.1 0.76 9.7 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif zf-UDP PF14569.6 ORY41314.1 - 0.089 12.9 2.4 0.21 11.7 2.4 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-ANAPC11 PF12861.7 ORY41314.1 - 0.22 11.6 2.2 0.44 10.6 2.2 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 ORY41314.1 - 0.23 11.6 4.2 0.48 10.6 4.2 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zn_ribbon_17 PF17120.5 ORY41314.1 - 1.9 8.2 6.9 3.3 7.4 6.9 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C2H2 PF00096.26 ORY41315.1 - 9.5e-08 32.1 18.1 0.00034 20.9 1.6 3.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY41315.1 - 7.5e-06 26.4 17.2 0.00056 20.5 1.2 3.7 4 0 0 4 4 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY41315.1 - 1.4e-05 25.2 1.3 0.0022 18.2 0.0 2.9 2 1 1 3 3 3 1 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 ORY41315.1 - 0.00013 22.6 5.9 0.029 15.0 0.2 3.1 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-met PF12874.7 ORY41315.1 - 0.00013 22.3 1.6 0.17 12.3 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 ORY41315.1 - 0.0002 21.6 2.7 0.0002 21.6 2.7 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY41315.1 - 0.00041 20.3 8.2 0.017 15.1 0.3 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORY41315.1 - 0.00058 20.0 0.8 0.00073 19.7 0.8 1.2 1 0 0 1 1 1 1 Aberrant zinc-finger zf-Di19 PF05605.12 ORY41315.1 - 0.046 14.0 4.4 0.24 11.7 1.1 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 ORY41315.1 - 0.068 13.1 1.0 0.15 12.0 1.0 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.7 ORY41315.1 - 0.084 13.2 2.7 0.66 10.3 2.7 2.2 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_9 PF16293.5 ORY41315.1 - 0.38 10.6 2.5 5.3 7.0 0.1 3.1 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf_C2H2_ZHX PF18387.1 ORY41315.1 - 1.4 8.6 7.0 7.1 6.4 0.2 3.4 3 1 1 4 4 4 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF1793 PF08760.11 ORY41316.1 - 0.023 15.1 2.7 0.043 14.3 2.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1793) AAA_11 PF13086.6 ORY41317.1 - 9.6e-43 146.8 0.2 5.5e-26 91.9 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 ORY41317.1 - 4.2e-14 52.7 0.0 4.2e-13 49.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY41317.1 - 6.3e-11 42.8 0.0 3.7e-10 40.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.6 ORY41317.1 - 2.8e-10 40.2 0.0 6.1e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 ORY41317.1 - 2.3e-06 27.7 0.0 4.9e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 ORY41317.1 - 0.0005 19.7 0.0 0.0013 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY41317.1 - 0.0007 19.9 0.1 0.0025 18.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY41317.1 - 0.00092 19.6 0.1 0.0028 18.1 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.18 ORY41317.1 - 0.0028 17.4 0.0 1.7 8.3 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.9 ORY41317.1 - 0.0038 16.2 0.0 0.0073 15.3 0.0 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Helicase_RecD PF05127.14 ORY41317.1 - 0.004 17.0 0.0 0.015 15.2 0.0 2.0 1 1 0 1 1 1 1 Helicase AAA_6 PF12774.7 ORY41317.1 - 0.008 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA PF00004.29 ORY41317.1 - 0.016 15.6 0.0 0.044 14.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.21 ORY41317.1 - 0.017 14.6 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_33 PF13671.6 ORY41317.1 - 0.022 14.9 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 ORY41317.1 - 0.028 13.8 0.0 0.067 12.5 0.0 1.6 1 1 0 1 1 1 0 KaiC ANAPC5 PF12862.7 ORY41317.1 - 0.056 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 CbiA PF01656.23 ORY41317.1 - 0.068 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.9 ORY41317.1 - 0.069 12.4 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 ORY41317.1 - 0.081 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 ORY41317.1 - 0.1 13.1 0.0 0.26 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 ORY41317.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 ORY41317.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.16 ORY41317.1 - 0.12 11.9 0.0 0.69 9.3 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_31 PF13614.6 ORY41317.1 - 0.15 12.0 0.1 0.59 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 ORY41317.1 - 0.16 11.1 0.0 6.8 5.8 0.0 2.4 2 0 0 2 2 2 0 PIF1-like helicase AAA_14 PF13173.6 ORY41317.1 - 0.17 11.9 0.0 7.6 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain ELP6 PF09807.9 ORY41318.1 - 8.3e-18 64.7 1.9 3.3e-10 39.8 0.9 2.0 1 1 1 2 2 2 2 Elongation complex protein 6 Elong_Iki1 PF10483.9 ORY41318.1 - 0.017 14.6 0.1 0.023 14.2 0.1 1.1 1 0 0 1 1 1 0 Elongator subunit Iki1 TFIIA PF03153.13 ORY41319.1 - 0.33 10.9 24.7 0.44 10.5 24.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 ORY41319.1 - 2 6.6 21.5 2.5 6.3 21.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-C2H2 PF00096.26 ORY41320.1 - 1.4e-08 34.7 13.2 1.2e-05 25.5 1.8 2.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY41320.1 - 6.1e-07 29.7 9.9 0.00021 21.9 1.8 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY41320.1 - 7.5e-06 26.1 2.3 7.5e-06 26.1 2.3 2.7 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY41320.1 - 0.00011 22.3 1.1 0.00042 20.5 0.1 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY41320.1 - 0.00012 22.3 1.5 0.037 14.4 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY41320.1 - 0.0048 16.9 5.5 0.013 15.5 0.7 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 ORY41320.1 - 0.01 16.1 3.6 0.13 12.6 1.8 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 ORY41320.1 - 0.034 14.1 1.3 0.034 14.1 1.3 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Rad50_zn_hook PF04423.14 ORY41320.1 - 0.056 13.3 0.4 0.091 12.6 0.4 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif zf_ZIC PF18366.1 ORY41320.1 - 0.16 12.1 6.6 7.2 6.8 0.0 3.6 3 1 0 3 3 3 0 Zic proteins zinc finger domain eIF-5_eIF-2B PF01873.17 ORY41321.1 - 0.043 13.7 0.1 0.046 13.6 0.1 1.1 1 0 0 1 1 1 0 Domain found in IF2B/IF5 SKA1 PF07160.12 ORY41322.1 - 0.0023 17.8 0.0 0.0044 16.9 0.0 1.5 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 DUF4495 PF14906.6 ORY41323.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4495) SNF2_N PF00176.23 ORY41324.1 - 8.9e-29 100.3 0.1 2.4e-28 98.9 0.1 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 ORY41324.1 - 3.5e-11 42.8 5.0 8.4e-11 41.6 5.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY41324.1 - 5.2e-10 39.5 6.1 1.6e-09 37.9 6.1 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 ORY41324.1 - 1.7e-08 34.2 5.7 3.5e-08 33.3 5.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ORY41324.1 - 3.2e-06 26.9 7.1 3.2e-06 26.9 7.1 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY41324.1 - 3.8e-06 26.5 1.7 1.4e-05 24.7 1.7 2.1 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 ORY41324.1 - 4.1e-06 26.6 5.7 1.2e-05 25.1 5.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 ORY41324.1 - 2.7e-05 24.2 0.0 8e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 ORY41324.1 - 2.8e-05 23.9 5.8 2.8e-05 23.9 5.8 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 ORY41324.1 - 3.3e-05 23.7 2.2 0.00014 21.7 1.9 2.2 2 0 0 2 2 1 1 zf-RING of BARD1-type protein Helicase_C PF00271.31 ORY41324.1 - 4.2e-05 23.8 0.0 0.00014 22.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 ORY41324.1 - 6.9e-05 22.8 7.0 0.00016 21.6 7.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 ORY41324.1 - 0.00013 21.5 0.5 0.00023 20.7 0.5 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger UPF0547 PF10571.9 ORY41324.1 - 0.00046 20.2 0.0 8.2 6.6 0.0 2.6 1 1 1 2 2 2 1 Uncharacterised protein family UPF0547 zf-RING_4 PF14570.6 ORY41324.1 - 0.0041 16.9 6.2 0.0091 15.8 6.2 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DZR PF12773.7 ORY41324.1 - 0.032 14.3 4.7 0.072 13.1 4.7 1.6 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 ORY41324.1 - 0.15 12.4 2.6 0.38 11.1 2.6 1.7 1 0 0 1 1 1 0 zinc-ribbon zf-rbx1 PF12678.7 ORY41324.1 - 0.29 11.4 3.9 0.84 10.0 3.9 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 ORY41324.1 - 0.3 11.3 6.4 0.063 13.4 2.7 1.8 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING ABC_tran PF00005.27 ORY41325.1 - 2.2e-56 190.2 0.1 1.2e-33 116.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORY41325.1 - 3.6e-51 174.4 19.5 1.4e-36 126.5 4.0 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ORY41325.1 - 1.2e-10 41.2 1.2 0.00019 20.9 0.0 4.3 3 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY41325.1 - 3.3e-06 27.6 0.6 0.016 15.6 0.2 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 ORY41325.1 - 3.9e-06 26.9 0.2 0.034 14.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY41325.1 - 6e-05 23.0 0.3 0.11 12.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 ORY41325.1 - 6e-05 22.7 1.3 0.021 14.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF87 PF01935.17 ORY41325.1 - 6.4e-05 23.2 1.5 0.15 12.1 0.2 2.6 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_23 PF13476.6 ORY41325.1 - 0.00088 19.8 0.3 0.81 10.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 ORY41325.1 - 0.0015 18.3 0.3 0.033 14.0 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ORY41325.1 - 0.0016 18.8 2.3 0.69 10.2 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 ORY41325.1 - 0.0028 17.5 0.5 2.4 7.9 0.0 3.8 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 ORY41325.1 - 0.0036 16.8 0.4 2.8 7.4 0.1 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 ORY41325.1 - 0.0048 16.6 0.6 5.7 6.6 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein DUF815 PF05673.13 ORY41325.1 - 0.013 14.7 1.4 0.068 12.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 ORY41325.1 - 0.018 14.8 1.5 0.98 9.1 0.1 2.9 3 1 0 3 3 2 0 AAA domain MobB PF03205.14 ORY41325.1 - 0.02 14.8 0.9 3.7 7.4 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 ORY41325.1 - 0.021 14.1 1.4 4.2 6.6 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.23 ORY41325.1 - 0.052 13.6 2.2 2.3 8.3 0.1 2.5 2 0 0 2 2 2 0 Dynamin family AAA_5 PF07728.14 ORY41325.1 - 0.056 13.5 1.7 15 5.6 0.0 3.5 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 ORY41325.1 - 0.069 12.7 0.2 15 5.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 ORY41325.1 - 0.069 13.4 0.6 14 5.9 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Pico_P2B PF01552.17 ORY41325.1 - 0.11 12.7 0.3 15 5.8 0.0 3.4 3 0 0 3 3 3 0 Picornavirus 2B protein ATP-synt_ab PF00006.25 ORY41325.1 - 0.11 12.2 0.0 12 5.4 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 ORY41325.1 - 0.17 11.2 0.2 8.3 5.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 ORY41325.1 - 0.19 11.5 0.1 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ORY41325.1 - 4 7.3 5.7 40 4.1 0.0 3.2 3 0 0 3 3 3 0 NACHT domain DUF45 PF01863.17 ORY41326.1 - 0.13 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 DUF4290 PF14123.6 ORY41326.1 - 0.13 11.8 0.4 8.5 5.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4290) Hit1_C PF18268.1 ORY41327.1 - 0.075 13.2 2.2 8.7 6.6 0.0 3.8 3 0 0 3 3 3 0 Hit1 C-terminal CTU2 PF10288.9 ORY41327.1 - 2.6 8.3 7.1 4.4 7.6 0.7 3.5 3 0 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-RanBP PF00641.18 ORY41327.1 - 3.2 7.1 4.9 0.68 9.3 0.8 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others 7tm_3 PF00003.22 ORY41328.1 - 9.5e-11 41.9 8.2 1.2e-10 41.6 8.2 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 ORY41329.1 - 2.4e-18 66.4 0.0 3.4e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region NAD_kinase PF01513.21 ORY41330.1 - 5.5e-52 176.8 0.0 1.2e-51 175.7 0.0 1.4 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 ORY41330.1 - 0.16 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Fer4 PF00037.27 ORY41331.1 - 2.3e-15 55.7 15.9 5.1e-09 35.6 4.9 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 ORY41331.1 - 3.3e-14 53.2 10.7 4.7e-14 52.7 10.7 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 ORY41331.1 - 2.4e-11 44.4 9.9 3.7e-06 27.8 0.7 2.1 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 ORY41331.1 - 8.9e-11 41.7 22.5 1.4e-07 31.5 12.9 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 ORY41331.1 - 1.4e-10 41.1 4.6 9e-05 22.5 0.5 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 ORY41331.1 - 1.3e-09 38.1 10.7 2.1e-09 37.4 10.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 ORY41331.1 - 1.6e-08 34.3 17.5 4.6e-05 23.3 4.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 ORY41331.1 - 2.5e-08 34.2 22.1 8.1e-06 26.2 12.0 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 ORY41331.1 - 3.6e-07 29.9 12.3 0.0017 18.3 2.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 ORY41331.1 - 9.4e-07 28.9 10.6 0.00015 22.0 2.0 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_13 PF13370.6 ORY41331.1 - 3.7e-05 24.2 9.5 0.019 15.5 0.4 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_17 PF13534.6 ORY41331.1 - 5.8e-05 23.5 13.1 0.0022 18.5 13.5 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 ORY41331.1 - 0.0034 17.6 5.5 0.25 11.6 0.2 2.2 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 ORY41331.1 - 0.012 15.8 9.4 0.57 10.4 1.4 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 ORY41331.1 - 0.012 16.5 16.9 0.1 13.6 5.2 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 ORY41331.1 - 0.05 13.7 6.3 0.73 10.0 0.7 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S EPF PF17181.4 ORY41331.1 - 0.056 13.4 4.6 0.16 12.0 0.7 2.2 2 0 0 2 2 2 0 Epidermal patterning factor proteins Fer4_22 PF17179.4 ORY41331.1 - 0.12 13.3 12.4 1.3 10.0 2.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain HEPN_RES_NTD1 PF18870.1 ORY41331.1 - 0.12 12.6 0.2 0.21 11.8 0.2 1.4 1 0 0 1 1 1 0 HEPN/RES N-terminal domain 1 Fer4_15 PF13459.6 ORY41331.1 - 5.4 7.8 18.6 4.9 8.0 5.6 3.4 2 2 0 2 2 2 0 4Fe-4S single cluster domain RNase_PH PF01138.21 ORY41332.1 - 9.6e-14 52.0 0.0 1.9e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ORY41332.1 - 1e-05 25.5 0.1 3.4e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 DUF4618 PF15397.6 ORY41333.1 - 5.8e-08 32.5 26.7 5.8e-08 32.5 26.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4618) DUF1638 PF07796.11 ORY41333.1 - 0.41 10.7 4.0 0.95 9.5 4.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1638) WD40 PF00400.32 ORY41334.1 - 0.0017 19.1 10.3 6.6 7.8 0.1 5.4 5 0 0 5 5 5 1 WD domain, G-beta repeat Terminase_1 PF03354.15 ORY41334.1 - 0.042 12.4 0.1 0.08 11.5 0.1 1.4 1 0 0 1 1 1 0 Phage Terminase ANAPC4_WD40 PF12894.7 ORY41334.1 - 0.15 12.4 0.0 5.5 7.4 0.0 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain GAT PF03127.14 ORY41336.1 - 5.1e-10 39.5 0.2 1.4e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 GAT domain DUF202 PF02656.15 ORY41337.1 - 0.0081 16.6 1.5 0.011 16.1 0.4 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF202) OpuAC PF04069.12 ORY41338.1 - 1.8e-13 50.7 0.0 3e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 Substrate binding domain of ABC-type glycine betaine transport system Ephrin_rec_like PF07699.13 ORY41338.1 - 0.00019 21.1 3.5 0.00019 21.1 3.5 3.5 4 0 0 4 4 4 1 Putative ephrin-receptor like NCD3G PF07562.14 ORY41338.1 - 0.00042 20.2 1.1 0.00042 20.2 1.1 3.1 3 1 0 3 3 3 1 Nine Cysteines Domain of family 3 GPCR Furin-like_2 PF15913.5 ORY41338.1 - 1.7 8.8 12.5 1.7 8.8 4.7 2.5 2 0 0 2 2 2 0 Furin-like repeat, cysteine-rich DUF1035 PF06281.12 ORY41339.1 - 0.0037 17.2 2.1 0.01 15.8 0.7 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1035) TMEM95 PF15203.6 ORY41339.1 - 0.13 11.9 0.0 0.36 10.5 0.0 1.7 1 1 1 2 2 2 0 TMEM95 family CBF PF03914.17 ORY41340.1 - 0.051 13.6 0.1 7.6 6.5 0.0 3.0 2 1 1 3 3 3 0 CBF/Mak21 family Endotoxin_N PF03945.14 ORY41341.1 - 0.03 14.0 0.1 0.068 12.9 0.1 1.5 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain SAGA-Tad1 PF12767.7 ORY41342.1 - 0.23 11.2 4.5 6.8 6.3 0.1 2.4 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit Rootletin PF15035.6 ORY41344.1 - 0.00024 21.2 7.7 0.0004 20.5 7.7 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion PPPI_inhib PF14895.6 ORY41345.1 - 0.00026 20.3 0.1 0.0026 17.0 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 1 inhibitor CENP-F_leu_zip PF10473.9 ORY41346.1 - 0.00086 19.3 0.9 0.00098 19.2 0.9 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3153 PF11353.8 ORY41346.1 - 0.12 11.9 0.1 0.14 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) CLAMP PF14769.6 ORY41347.1 - 0.00026 21.4 0.1 0.00044 20.7 0.1 1.4 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Colipase_C PF02740.14 ORY41347.1 - 0.064 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Colipase, C-terminal domain CLAMP PF14769.6 ORY41348.1 - 8.5e-05 22.9 1.7 0.00017 22.0 1.7 1.5 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 Foie-gras_1 PF11817.8 ORY41348.1 - 0.067 12.8 0.1 0.086 12.4 0.1 1.1 1 0 0 1 1 1 0 Foie gras liver health family 1 Enkurin PF13864.6 ORY41349.1 - 7.6e-05 23.1 0.1 7.6e-05 23.1 0.1 3.7 3 1 0 3 3 3 1 Calmodulin-binding Macoilin PF09726.9 ORY41349.1 - 0.0014 17.3 13.6 0.0014 17.3 13.6 1.6 2 0 0 2 2 2 1 Macoilin family XRN_M PF17846.1 ORY41349.1 - 0.083 11.8 7.3 0.16 10.9 7.3 1.4 1 0 0 1 1 1 0 Xrn1 helical domain Nsp1_C PF05064.13 ORY41349.1 - 0.3 10.9 11.3 0.37 10.6 9.2 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region HAP1_N PF04849.13 ORY41349.1 - 3.9 6.6 25.9 0.48 9.6 20.3 2.3 2 1 1 3 3 3 0 HAP1 N-terminal conserved region DUF1664 PF07889.12 ORY41349.1 - 5 7.2 13.0 16 5.6 5.8 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) His_Phos_1 PF00300.22 ORY41352.1 - 1.8e-14 53.9 0.0 2.3e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DAO PF01266.24 ORY41353.1 - 2.4e-15 57.0 1.8 4.1e-10 39.8 0.1 2.5 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ORY41353.1 - 0.022 14.0 1.4 0.032 13.5 1.4 1.2 1 0 0 1 1 1 0 FAD binding domain IlvN PF07991.12 ORY41353.1 - 0.068 12.7 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain SQHop_cyclase_C PF13243.6 ORY41353.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain zf-CCHC PF00098.23 ORY41356.1 - 0.002 18.1 2.3 0.0031 17.5 2.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 ORY41356.1 - 0.022 14.6 4.3 0.022 14.6 4.3 1.6 2 0 0 2 2 2 0 Zinc knuckle DUF2040 PF09745.9 ORY41357.1 - 1.2e-33 115.7 12.6 1.2e-33 115.7 12.6 4.0 3 1 1 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) LRR_8 PF13855.6 ORY41357.1 - 1.3e-07 31.2 8.1 6.9e-06 25.7 0.7 4.1 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 ORY41357.1 - 0.00034 20.9 15.7 0.4 11.2 1.9 4.4 2 1 2 5 5 5 4 Leucine Rich repeats (2 copies) HTH_15 PF12324.8 ORY41357.1 - 0.16 11.9 0.7 0.43 10.5 0.1 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase LRR_1 PF00560.33 ORY41357.1 - 0.22 12.2 5.7 0.78 10.5 0.1 4.0 4 1 0 4 4 4 0 Leucine Rich Repeat F-box-like PF12937.7 ORY41359.1 - 7.2e-11 41.8 0.0 1.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORY41359.1 - 8e-07 28.9 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 F-box F-box PF00646.33 ORY41359.1 - 1.4e-06 28.0 0.0 2.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain DUF4423 PF14394.6 ORY41360.1 - 0.099 12.3 0.1 0.24 11.1 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) Fascin PF06268.13 ORY41362.1 - 2.2e-05 24.6 0.0 0.00069 19.8 0.0 2.2 1 1 1 2 2 2 2 Fascin domain FRG1 PF06229.12 ORY41362.1 - 0.00034 20.4 0.1 0.012 15.4 0.0 2.7 2 1 1 3 3 3 1 FRG1-like domain FGF PF00167.18 ORY41362.1 - 0.062 13.4 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Fibroblast growth factor Hemerythrin PF01814.23 ORY41363.1 - 7.9e-07 29.8 0.4 0.00089 19.9 0.0 2.2 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain DUF1322 PF07032.11 ORY41363.1 - 0.025 15.1 0.3 0.062 13.8 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1322) GH97_C PF14509.6 ORY41363.1 - 0.028 14.6 0.0 0.052 13.8 0.0 1.4 1 1 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation COX7C PF02935.16 ORY41363.1 - 0.067 13.5 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc MATalpha_HMGbox PF04769.12 ORY41363.1 - 0.15 11.3 0.2 0.23 10.7 0.2 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box TAF4 PF05236.14 ORY41364.1 - 1.1e-17 64.7 11.3 1.7e-09 37.9 8.5 4.4 3 2 2 5 5 5 2 Transcription initiation factor TFIID component TAF4 family DDHD PF02862.17 ORY41365.1 - 1.5e-16 61.3 3.4 1.9e-16 60.9 0.0 2.8 2 2 0 2 2 2 1 DDHD domain Hydrolase_4 PF12146.8 ORY41365.1 - 0.066 12.5 0.0 0.2 10.9 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Lipase_3 PF01764.25 ORY41365.1 - 0.072 13.0 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) SKA1 PF07160.12 ORY41365.1 - 0.4 10.5 5.5 0.053 13.4 0.6 1.9 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 ANF_receptor PF01094.28 ORY41366.1 - 1.4e-11 44.1 0.0 1.9e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 ORY41367.1 - 1.3e-07 31.6 10.1 1.6e-07 31.3 10.1 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR 7tm_3 PF00003.22 ORY41368.1 - 2.8e-15 56.7 18.8 5.7e-15 55.7 18.8 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 ORY41368.1 - 5.7e-08 32.3 0.1 9.1e-06 25.0 0.0 2.4 1 1 1 2 2 2 2 Receptor family ligand binding region FAD_binding_2 PF00890.24 ORY41369.1 - 7.1e-127 423.9 4.3 1.1e-126 423.4 4.3 1.3 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 ORY41369.1 - 8.7e-43 145.4 2.3 1.3e-42 144.8 2.3 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term GIDA PF01134.22 ORY41369.1 - 1e-05 24.8 1.3 0.0049 16.0 1.6 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 ORY41369.1 - 8.3e-05 21.9 0.2 0.02 14.1 0.1 2.5 2 0 0 2 2 2 2 Thi4 family Pyr_redox_2 PF07992.14 ORY41369.1 - 0.00046 19.5 2.3 0.0026 17.0 0.2 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY41369.1 - 0.0029 16.7 0.1 0.02 13.9 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 ORY41369.1 - 0.011 15.0 0.1 0.02 14.2 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 ORY41369.1 - 0.062 12.0 1.9 0.35 9.5 0.5 2.7 4 0 0 4 4 4 0 HI0933-like protein DAO PF01266.24 ORY41369.1 - 0.065 12.8 1.1 0.16 11.5 1.1 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase 7tm_3 PF00003.22 ORY41370.1 - 8e-07 29.0 24.3 2.2e-06 27.6 24.3 1.8 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 ORY41370.1 - 0.00033 19.9 0.4 0.32 10.0 0.1 3.0 1 1 1 2 2 2 2 Receptor family ligand binding region TMF_DNA_bd PF12329.8 ORY41371.1 - 0.014 15.3 5.7 0.014 15.3 5.7 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 ORY41371.1 - 0.43 10.7 10.0 0.46 10.6 1.4 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1664 PF07889.12 ORY41371.1 - 0.7 9.9 5.5 0.39 10.8 0.3 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF3130 PF11328.8 ORY41371.1 - 1.2 9.5 4.8 1.8 8.9 0.6 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3130 Fez1 PF06818.15 ORY41371.1 - 2.4 8.6 11.6 11 6.4 1.2 2.4 1 1 1 2 2 2 0 Fez1 Tup_N PF08581.10 ORY41371.1 - 2.8 8.3 7.0 19 5.6 1.0 2.7 2 1 0 2 2 2 0 Tup N-terminal DUF4368 PF14287.6 ORY41372.1 - 0.087 13.1 3.0 0.28 11.5 3.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4368) Aconitase_C PF00694.19 ORY41372.1 - 0.14 12.4 3.2 0.36 11.2 0.3 2.6 2 1 0 2 2 2 0 Aconitase C-terminal domain DUF5041 PF16444.5 ORY41372.1 - 1.7 8.8 5.3 7.2 6.8 1.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5041) Filament PF00038.21 ORY41372.1 - 1.8 8.1 51.6 1.1 8.8 40.3 3.2 1 1 0 2 2 2 0 Intermediate filament protein BCL_N PF04714.13 ORY41372.1 - 2 8.5 5.4 22 5.2 0.0 3.2 3 0 0 3 3 3 0 BCL7, N-terminal conserver region Spc7 PF08317.11 ORY41372.1 - 2.8 6.7 53.1 0.31 9.9 21.5 4.1 2 1 1 4 4 4 0 Spc7 kinetochore protein HTH_57 PF18679.1 ORY41372.1 - 5.8 7.3 7.5 1.2 9.5 2.2 2.6 2 1 0 2 2 2 0 ThcOx helix turn helix domain Peripla_BP_2 PF01497.18 ORY41372.1 - 9.3 5.7 7.6 7.6 6.0 1.2 2.5 2 1 1 3 3 3 0 Periplasmic binding protein COX5A PF02284.16 ORY41373.1 - 7.6e-25 86.9 0.1 9.1e-25 86.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Pecanex_C PF05041.15 ORY41374.1 - 2.1e-10 40.5 0.2 4e-10 39.7 0.2 1.4 1 0 0 1 1 1 1 Pecanex protein (C-terminus) Acetyltransf_4 PF13420.7 ORY41375.1 - 1.5e-25 90.2 0.0 1.8e-25 89.9 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORY41375.1 - 4.5e-10 40.3 0.0 5.5e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY41375.1 - 2.2e-09 37.6 0.0 2.7e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 ORY41375.1 - 3.1e-08 33.5 0.0 5.2e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 ORY41375.1 - 2.9e-05 24.0 0.0 3.8e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY41375.1 - 0.0003 21.1 0.0 0.00048 20.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 ORY41375.1 - 0.0015 18.2 0.0 0.12 11.9 0.0 2.1 1 1 1 2 2 2 2 GNAT acetyltransferase GSHPx PF00255.19 ORY41376.1 - 4.7e-30 103.3 0.0 6.5e-30 102.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 ORY41376.1 - 0.041 13.8 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Acetyltransf_1 PF00583.25 ORY41377.1 - 2.3e-10 40.7 0.0 3.7e-10 40.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 ORY41377.1 - 9.8e-06 26.3 0.0 1.4e-05 25.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY41377.1 - 0.011 15.7 0.1 0.02 14.8 0.1 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY41377.1 - 0.015 15.7 0.0 0.022 15.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_16 PF05301.11 ORY41377.1 - 0.046 13.5 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 Acetyltransf_1 PF00583.25 ORY41378.1 - 2.4e-14 53.6 0.0 4.1e-14 52.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY41378.1 - 5.8e-09 36.3 0.0 8.3e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY41378.1 - 2.6e-08 33.8 0.0 3.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORY41378.1 - 3.8e-05 24.4 0.0 4.5e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORY41378.1 - 4.4e-05 23.7 0.0 6.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY41378.1 - 0.0013 18.7 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 ORY41378.1 - 0.029 14.0 0.0 0.037 13.7 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 ORY41378.1 - 0.074 12.5 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative acetyl-transferase GNAT_acetyltr_2 PF13718.6 ORY41378.1 - 0.1 12.0 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Not3 PF04065.15 ORY41379.1 - 1e-80 270.5 19.1 2e-80 269.6 19.1 1.5 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 ORY41379.1 - 2.2e-36 124.8 15.4 5e-36 123.7 15.0 1.9 1 1 0 1 1 1 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.9 ORY41379.1 - 0.014 15.2 3.9 0.036 13.9 3.9 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Syntaxin_2 PF14523.6 ORY41379.1 - 0.12 12.8 0.3 0.12 12.8 0.3 3.5 3 0 0 3 3 3 0 Syntaxin-like protein MYO10_CC PF16735.5 ORY41379.1 - 3.6 7.8 6.6 9.8 6.4 0.3 3.4 3 0 0 3 3 3 0 Unconventional myosin-X coiled coil domain Rx_N PF18052.1 ORY41379.1 - 4.8 7.5 12.2 2.7 8.3 0.7 3.7 1 1 2 3 3 3 0 Rx N-terminal domain YlqD PF11068.8 ORY41379.1 - 5.5 7.4 12.0 0.28 11.5 2.3 2.6 1 1 1 2 2 2 0 YlqD protein TIR_2 PF13676.6 ORY41380.1 - 1.2e-15 58.1 0.0 3.1e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 TIR domain C2 PF00168.30 ORY41380.1 - 1.7e-11 44.3 0.2 4e-11 43.1 0.2 1.6 1 0 0 1 1 1 1 C2 domain TIR PF01582.20 ORY41380.1 - 0.0063 16.3 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 TIR domain DUF1863 PF08937.11 ORY41380.1 - 0.054 13.8 0.1 0.21 11.9 0.1 2.0 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) SAM_PNT PF02198.16 ORY41380.1 - 0.075 13.0 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain TIR_2 PF13676.6 ORY41381.1 - 2.3e-18 66.9 0.0 3.3e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 ORY41381.1 - 0.0089 15.8 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 TIR domain Glyco_hydro_20 PF00728.22 ORY41383.1 - 8e-79 265.6 0.0 1.3e-78 264.9 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 ORY41383.1 - 2.3e-10 41.3 0.2 4.4e-10 40.4 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 ORY41383.1 - 8.8e-07 29.7 0.7 7.2e-06 26.7 0.1 2.5 2 1 0 3 3 3 1 beta-acetyl hexosaminidase like RhoGAP PF00620.27 ORY41384.1 - 8e-07 29.0 0.2 1.2e-06 28.5 0.2 1.2 1 0 0 1 1 1 1 RhoGAP domain Rho_GDI PF02115.17 ORY41385.1 - 1.9e-63 213.8 0.0 2.2e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Ribosomal_L12 PF00542.19 ORY41386.1 - 1.4e-21 76.6 9.5 1.6e-21 76.4 9.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain NKAP PF15692.5 ORY41386.1 - 0.029 15.1 1.0 0.055 14.2 1.0 1.4 1 0 0 1 1 1 0 NF-kappa-B-activating protein Trm5_N PF18093.1 ORY41386.1 - 0.074 13.0 0.2 0.17 11.8 0.2 1.6 1 0 0 1 1 1 0 tRNA methyltransferase 5 N-terminal domain zf-C2H2 PF00096.26 ORY41387.1 - 2.8e-12 46.4 12.5 0.00012 22.4 1.0 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY41387.1 - 2.1e-08 34.3 9.8 0.048 14.5 0.4 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY41387.1 - 0.0016 18.7 5.6 0.64 10.4 0.0 3.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 ORY41387.1 - 0.01 16.2 11.0 1.8 9.2 0.3 3.7 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_8 PF15909.5 ORY41387.1 - 0.012 15.9 3.2 0.03 14.6 2.3 2.1 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf_ZIC PF18366.1 ORY41387.1 - 0.014 15.5 4.2 0.88 9.7 0.1 2.9 3 0 0 3 3 3 0 Zic proteins zinc finger domain zf-RAG1 PF10426.9 ORY41387.1 - 0.018 15.2 3.6 0.33 11.1 0.2 2.8 2 1 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain zf-C2H2_aberr PF17017.5 ORY41387.1 - 0.024 14.8 6.0 0.34 11.0 0.1 3.1 1 1 2 3 3 3 0 Aberrant zinc-finger zf-met PF12874.7 ORY41387.1 - 0.041 14.3 4.7 4.4 7.8 0.2 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type TPR_12 PF13424.6 ORY41388.1 - 1.9e-12 47.3 4.2 0.00077 19.7 0.2 3.5 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY41388.1 - 1.8e-07 30.7 4.9 0.12 12.6 0.3 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY41388.1 - 2.1e-07 30.6 4.3 0.027 14.7 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY41388.1 - 5.6e-07 29.1 5.2 0.49 10.3 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat zf-MYND PF01753.18 ORY41388.1 - 9.3e-07 28.8 5.8 1.6e-06 28.0 5.8 1.4 1 0 0 1 1 1 1 MYND finger TPR_10 PF13374.6 ORY41388.1 - 0.00094 19.0 4.0 0.094 12.6 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-Mss51 PF13824.6 ORY41388.1 - 0.0021 18.1 2.7 0.036 14.2 2.7 2.5 1 1 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 TPR_17 PF13431.6 ORY41388.1 - 0.11 12.9 0.1 39 4.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY41388.1 - 2.4 8.4 5.5 24 5.3 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY41388.1 - 2.7 7.7 6.9 0.62 9.8 0.1 3.1 4 0 0 4 4 4 0 TPR repeat TPR_16 PF13432.6 ORY41388.1 - 4 8.2 8.8 15 6.3 0.2 3.8 2 2 0 3 3 3 0 Tetratricopeptide repeat MSA-2c PF12238.8 ORY41389.1 - 2.5 8.1 4.3 3.2 7.7 4.3 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c Kinesin PF00225.23 ORY41390.1 - 2.4e-15 56.3 0.1 1.6e-10 40.4 0.1 2.5 1 1 1 2 2 2 2 Kinesin motor domain HAP1_N PF04849.13 ORY41390.1 - 0.78 8.9 50.5 2.2 7.4 5.6 6.1 5 1 0 5 5 5 0 HAP1 N-terminal conserved region GTSE1_N PF15259.6 ORY41390.1 - 1.7 8.8 10.6 1.3 9.2 2.6 3.2 2 1 0 2 2 2 0 G-2 and S-phase expressed 1 FPP PF05911.11 ORY41391.1 - 0.00021 19.7 99.3 0.005 15.1 19.2 4.2 1 1 3 4 4 4 3 Filament-like plant protein, long coiled-coil TPR_MLP1_2 PF07926.12 ORY41391.1 - 0.00038 20.5 16.1 0.00038 20.5 16.1 8.7 2 2 7 9 9 9 4 TPR/MLP1/MLP2-like protein Lectin_N PF03954.14 ORY41391.1 - 0.003 17.3 5.8 0.003 17.3 5.8 6.7 1 1 4 5 5 5 2 Hepatic lectin, N-terminal domain Fib_alpha PF08702.10 ORY41391.1 - 0.0065 16.7 9.5 0.0065 16.7 9.5 6.7 1 1 7 9 9 9 2 Fibrinogen alpha/beta chain family Striatin PF08232.12 ORY41391.1 - 0.097 13.3 67.2 0.033 14.8 19.5 7.1 1 1 5 7 7 7 0 Striatin family DUF4472 PF14739.6 ORY41391.1 - 0.15 12.8 84.2 0.61 10.9 8.5 7.7 2 2 6 8 8 8 0 Domain of unknown function (DUF4472) Filament PF00038.21 ORY41391.1 - 0.66 9.5 92.1 0.074 12.6 3.4 6.2 1 1 2 3 3 3 0 Intermediate filament protein Myosin_tail_1 PF01576.19 ORY41391.1 - 1.6 6.4 104.7 0.3 8.8 19.5 4.5 1 1 2 3 3 3 0 Myosin tail ABC_tran_CTD PF16326.5 ORY41392.1 - 0.0022 18.2 56.3 0.77 10.0 0.3 8.1 4 2 4 8 8 8 5 ABC transporter C-terminal domain MAD PF05557.13 ORY41392.1 - 0.0092 14.4 50.0 0.038 12.3 13.2 3.9 2 2 1 3 3 3 2 Mitotic checkpoint protein FPP PF05911.11 ORY41392.1 - 0.011 14.0 43.8 0.022 13.0 43.8 1.4 1 1 0 1 1 1 0 Filament-like plant protein, long coiled-coil SlyX PF04102.12 ORY41392.1 - 0.024 15.2 47.8 0.5 11.0 4.4 8.2 3 3 6 9 9 9 0 SlyX EzrA PF06160.12 ORY41392.1 - 0.038 12.2 41.9 0.74 7.9 20.6 3.2 2 2 0 2 2 2 0 Septation ring formation regulator, EzrA Endonuc_Holl PF10107.9 ORY41392.1 - 0.072 12.9 0.2 0.072 12.9 0.2 3.6 2 1 2 5 5 5 0 Endonuclease related to archaeal Holliday junction resolvase NPV_P10 PF05531.12 ORY41392.1 - 0.15 12.6 29.6 4.4 7.8 0.1 7.0 3 3 4 7 7 7 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 ORY41392.1 - 0.64 8.9 52.8 0.19 10.6 4.3 4.7 2 2 1 4 4 4 0 Spc7 kinetochore protein MetOD2 PF18548.1 ORY41392.1 - 0.85 9.8 25.9 0.52 10.4 0.1 5.1 3 2 2 5 5 5 0 Metanogen output domain 2 Lebercilin PF15619.6 ORY41392.1 - 1.4 8.5 55.1 0.12 12.0 5.6 5.9 2 2 2 5 5 5 0 Ciliary protein causing Leber congenital amaurosis disease APG17 PF04108.12 ORY41392.1 - 1.7 7.6 34.1 0.64 9.1 15.1 3.3 2 1 2 4 4 4 0 Autophagy protein Apg17 Exonuc_VII_L PF02601.15 ORY41392.1 - 1.8 8.1 38.9 0.97 8.9 9.0 3.8 1 1 1 3 3 3 0 Exonuclease VII, large subunit OmpH PF03938.14 ORY41392.1 - 1.9 8.8 40.3 0.71 10.2 2.1 4.9 3 1 1 4 4 4 0 Outer membrane protein (OmpH-like) GAS PF13851.6 ORY41392.1 - 2 7.7 47.7 0.98 8.7 3.9 4.4 2 2 2 4 4 4 0 Growth-arrest specific micro-tubule binding MscS_porin PF12795.7 ORY41392.1 - 2.6 7.5 54.5 0.56 9.7 16.9 5.8 2 2 3 5 5 5 0 Mechanosensitive ion channel porin domain DUF1664 PF07889.12 ORY41392.1 - 3.2 7.8 31.6 0.24 11.4 3.7 5.0 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) DHR10 PF18595.1 ORY41392.1 - 4.9 7.3 50.0 3 7.9 6.8 5.3 4 2 1 5 5 5 0 Designed helical repeat protein 10 domain HIP1_clath_bdg PF16515.5 ORY41392.1 - 8.4 7.1 53.8 1 10.0 6.2 6.4 2 2 2 5 5 5 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Med9 PF07544.13 ORY41392.1 - 8.7 6.5 30.3 0.11 12.6 1.9 5.3 3 2 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 zf-C2H2_4 PF13894.6 ORY41393.1 - 1.4e-09 38.0 6.4 0.00025 21.6 2.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY41393.1 - 1.5e-09 37.8 7.9 0.00059 20.1 0.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 ORY41393.1 - 1.4e-07 31.6 4.4 0.0021 18.3 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY41393.1 - 2.1e-07 30.8 3.5 0.009 16.0 1.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY41393.1 - 4.8e-06 26.7 7.1 0.034 14.6 1.0 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_2 PF12756.7 ORY41393.1 - 0.0014 18.9 5.7 0.21 11.9 0.8 2.3 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 ORY41393.1 - 0.0023 18.3 5.9 0.11 12.9 0.2 2.7 3 0 0 3 3 2 2 Zinc-finger of C2H2 type zf-C2HE PF16278.5 ORY41393.1 - 0.0075 16.7 2.2 0.24 11.9 0.6 2.3 1 1 1 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 ORY41393.1 - 0.028 14.5 5.5 1.8 8.7 0.5 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-FCS PF06467.14 ORY41393.1 - 0.032 14.2 0.8 1.7 8.6 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF1272 PF06906.11 ORY41393.1 - 0.1 12.7 2.2 0.91 9.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Elf1 PF05129.13 ORY41393.1 - 0.2 11.7 4.1 0.42 10.7 4.1 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-BED PF02892.15 ORY41393.1 - 0.29 11.2 6.4 3.2 7.8 1.5 2.5 1 1 1 2 2 2 0 BED zinc finger zf-nanos PF05741.13 ORY41393.1 - 0.34 11.2 2.1 0.72 10.1 2.1 1.5 1 0 0 1 1 1 0 Nanos RNA binding domain zf-C2HC_2 PF13913.6 ORY41393.1 - 0.41 10.6 9.1 1 9.3 0.9 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-LYAR PF08790.11 ORY41393.1 - 0.54 10.2 4.6 9.3 6.3 0.3 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 ORY41393.1 - 1.7 8.3 6.1 3.7 7.2 0.2 2.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-H2C2_5 PF13909.6 ORY41393.1 - 2.1 8.2 15.9 0.43 10.4 2.4 2.9 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 ORY41394.1 - 8.7e-07 29.1 6.2 2.9e-05 24.3 2.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY41394.1 - 8.6e-06 25.9 2.6 0.059 13.8 0.0 2.3 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY41394.1 - 0.0001 22.8 4.5 0.027 15.3 1.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 ORY41394.1 - 0.16 12.6 0.2 0.24 12.0 0.2 1.2 1 0 0 1 1 1 0 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 ORY41394.1 - 0.34 10.7 1.8 0.34 10.7 0.1 1.8 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 ORY41394.1 - 0.85 9.7 2.8 20 5.3 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.15 ORY41394.1 - 1.4 9.0 3.5 5.4 7.1 0.2 2.4 2 0 0 2 2 2 0 BED zinc finger Methyltransf_13 PF08421.11 ORY41395.1 - 0.16 12.2 0.0 0.65 10.3 0.0 2.1 2 0 0 2 2 2 0 Putative zinc binding domain MMACHC PF16690.5 ORY41396.1 - 9.9e-06 25.3 1.9 5.8e-05 22.8 0.1 2.5 2 1 0 2 2 2 1 Methylmalonic aciduria and homocystinuria type C family RRM_1 PF00076.22 ORY41397.1 - 2.1e-15 56.3 0.1 2e-09 37.2 0.0 3.2 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORY41397.1 - 0.002 18.2 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif Limkain-b1 PF11608.8 ORY41397.1 - 0.13 12.3 2.8 2.6 8.2 0.1 2.6 2 1 0 2 2 2 0 Limkain b1 PX PF00787.24 ORY41398.1 - 1.5e-07 31.4 3.1 5e-07 29.7 3.1 1.9 1 1 0 1 1 1 1 PX domain PB1 PF00564.24 ORY41398.1 - 1.7e-05 24.7 0.0 3.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 PB1 domain SH3_9 PF14604.6 ORY41398.1 - 0.00071 19.4 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY41398.1 - 0.0088 15.7 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY41398.1 - 0.03 13.9 0.0 0.064 12.9 0.0 1.6 1 0 0 1 1 1 0 SH3 domain EB1 PF03271.17 ORY41399.1 - 6.4e-11 42.3 1.7 1.1e-10 41.6 1.7 1.4 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 ORY41399.1 - 0.0029 17.8 0.1 0.0049 17.0 0.1 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Spo7 PF03907.13 ORY41400.1 - 0.086 12.3 0.2 0.14 11.6 0.2 1.3 1 0 0 1 1 1 0 Spo7-like protein DUF4401 PF14351.6 ORY41400.1 - 0.42 9.9 9.0 1.7 7.9 6.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4401) Cation_efflux PF01545.21 ORY41402.1 - 6.1e-14 52.2 0.3 8.3e-14 51.8 0.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORY41402.1 - 5.7e-13 48.8 0.3 1e-12 48.0 0.3 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter E1-E2_ATPase PF00122.20 ORY41403.1 - 3.9e-21 75.4 8.8 2.7e-20 72.6 0.0 3.6 3 1 1 4 4 4 2 E1-E2 ATPase Hydrolase PF00702.26 ORY41403.1 - 3.9e-15 56.7 0.3 1e-14 55.3 0.3 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY41403.1 - 5e-10 38.9 0.0 1.3e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 ORY41403.1 - 2.7e-08 33.8 0.0 6.7e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY41403.1 - 0.0091 15.8 1.6 0.029 14.1 0.1 2.5 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase Hexapep PF00132.24 ORY41404.1 - 1.1e-09 37.6 12.3 1.3e-07 31.1 4.4 4.2 3 2 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ORY41404.1 - 3.2e-07 30.0 2.4 5.1e-05 22.9 2.1 2.8 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 ORY41404.1 - 0.0018 17.3 0.4 0.0038 16.2 0.1 1.5 1 1 0 2 2 2 1 L-fucokinase ADH_N PF08240.12 ORY41405.1 - 1.5e-23 82.8 3.3 2.9e-23 81.8 3.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY41405.1 - 3.2e-23 82.1 0.1 5.8e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 ORY41405.1 - 0.022 14.1 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RhoGAP PF00620.27 ORY41407.1 - 7.1e-07 29.2 0.1 1.5e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain RhoGAP PF00620.27 ORY41408.1 - 2.2e-23 82.8 0.1 2.1e-12 47.1 0.0 2.4 2 0 0 2 2 2 2 RhoGAP domain RhoGAP PF00620.27 ORY41409.1 - 1.6e-11 44.2 0.0 2.4e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain Peptidase_M3 PF01432.20 ORY41411.1 - 8.6e-107 358.2 0.0 1.2e-106 357.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 ORY41411.1 - 0.062 12.9 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like TIR_2 PF13676.6 ORY41412.1 - 1.8e-06 28.6 0.0 3.3e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 TIR domain DUF3450 PF11932.8 ORY41413.1 - 0.0011 18.3 1.3 0.0014 17.9 1.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) ZapB PF06005.12 ORY41413.1 - 0.0012 19.2 5.1 0.0017 18.8 5.1 1.3 1 1 0 1 1 1 1 Cell division protein ZapB Nsp1_C PF05064.13 ORY41413.1 - 0.0012 18.6 1.1 0.0014 18.4 1.1 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region BLOC1_2 PF10046.9 ORY41413.1 - 0.0036 17.6 1.0 0.0047 17.2 1.0 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 ORY41413.1 - 0.0047 16.8 1.0 0.0053 16.6 1.0 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 BST2 PF16716.5 ORY41413.1 - 0.0052 17.3 2.4 0.0065 17.0 2.4 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 GAS PF13851.6 ORY41413.1 - 0.0093 15.3 3.1 0.01 15.2 3.1 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding CCDC92 PF14916.6 ORY41413.1 - 0.015 15.0 3.3 0.027 14.2 3.2 1.5 1 1 0 1 1 1 0 Coiled-coil domain of unknown function Herpes_UL6 PF01763.16 ORY41413.1 - 0.021 13.4 1.8 0.021 13.3 1.8 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like YabA PF06156.13 ORY41413.1 - 0.022 15.4 1.5 0.027 15.1 1.5 1.2 1 0 0 1 1 1 0 Initiation control protein YabA Sec34 PF04136.15 ORY41413.1 - 0.023 14.5 1.4 0.026 14.4 1.4 1.1 1 0 0 1 1 1 0 Sec34-like family DUF948 PF06103.11 ORY41413.1 - 0.026 14.8 0.5 0.036 14.3 0.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) HlyD_D23 PF16576.5 ORY41413.1 - 0.028 13.6 1.1 0.03 13.5 1.1 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion TMF_DNA_bd PF12329.8 ORY41413.1 - 0.032 14.2 1.0 0.032 14.2 1.0 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding APG6_N PF17675.1 ORY41413.1 - 0.066 13.7 2.6 0.095 13.2 2.6 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region Fib_alpha PF08702.10 ORY41413.1 - 0.11 12.7 3.1 0.42 10.8 3.1 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 ORY41413.1 - 0.12 12.6 1.9 0.24 11.6 1.9 1.5 1 0 0 1 1 1 0 Haemolysin XhlA USP8_interact PF08941.10 ORY41413.1 - 0.13 12.1 2.2 0.15 11.9 2.2 1.1 1 0 0 1 1 1 0 USP8 interacting DUF3592 PF12158.8 ORY41413.1 - 0.14 12.2 0.1 0.16 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) SlyX PF04102.12 ORY41413.1 - 0.23 12.1 4.0 1.2 9.9 4.0 2.0 1 1 0 1 1 1 0 SlyX DivIC PF04977.15 ORY41413.1 - 1.4 8.8 5.2 5.8 6.8 5.1 2.0 1 1 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 ORY41413.1 - 2.2 8.5 4.9 6.7 6.9 1.8 2.3 1 1 1 2 2 2 0 Basic region leucine zipper DCA16 PF15349.6 ORY41416.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.0 2 0 0 2 2 2 0 DDB1- and CUL4-associated factor 16 Dynamin_N PF00350.23 ORY41416.1 - 0.2 11.7 0.1 0.2 11.7 0.1 2.7 3 1 0 3 3 3 0 Dynamin family TFIIA PF03153.13 ORY41416.1 - 2.7 7.9 20.3 0.11 12.5 6.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3450 PF11932.8 ORY41418.1 - 0.00077 18.8 1.2 0.001 18.4 1.0 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) Nsp1_C PF05064.13 ORY41418.1 - 0.00095 19.0 1.0 0.0011 18.8 1.0 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region ZapB PF06005.12 ORY41418.1 - 0.0011 19.4 4.4 0.0014 19.0 4.4 1.3 1 1 0 1 1 1 1 Cell division protein ZapB BLOC1_2 PF10046.9 ORY41418.1 - 0.0022 18.2 0.8 0.0029 17.9 0.8 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 ORY41418.1 - 0.0029 17.5 0.9 0.0033 17.3 0.9 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 BST2 PF16716.5 ORY41418.1 - 0.0042 17.6 2.2 0.0053 17.3 2.2 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 GAS PF13851.6 ORY41418.1 - 0.0057 16.0 2.8 0.0064 15.9 2.8 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding YabA PF06156.13 ORY41418.1 - 0.018 15.6 1.2 0.022 15.4 1.2 1.2 1 0 0 1 1 1 0 Initiation control protein YabA CCDC92 PF14916.6 ORY41418.1 - 0.019 14.7 3.5 0.034 13.9 3.3 1.6 1 1 0 1 1 1 0 Coiled-coil domain of unknown function Cluap1 PF10234.9 ORY41418.1 - 0.019 14.4 1.4 0.02 14.3 1.4 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Herpes_UL6 PF01763.16 ORY41418.1 - 0.019 13.5 1.5 0.02 13.5 1.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like HlyD_D23 PF16576.5 ORY41418.1 - 0.027 13.7 1.0 0.029 13.6 1.0 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion TMF_DNA_bd PF12329.8 ORY41418.1 - 0.034 14.1 1.1 0.034 14.1 1.1 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Rab_bind PF16704.5 ORY41418.1 - 0.034 14.2 0.3 2.8 8.1 0.1 2.3 1 1 1 2 2 2 0 Rab binding domain Sec34 PF04136.15 ORY41418.1 - 0.035 14.0 1.3 0.039 13.8 1.3 1.1 1 0 0 1 1 1 0 Sec34-like family APG6_N PF17675.1 ORY41418.1 - 0.046 14.3 2.7 0.062 13.8 2.7 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF948 PF06103.11 ORY41418.1 - 0.077 13.3 0.4 0.11 12.8 0.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 ORY41418.1 - 0.13 12.5 2.9 0.52 10.5 2.8 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 ORY41418.1 - 0.14 12.4 1.7 0.27 11.5 1.7 1.5 1 0 0 1 1 1 0 Haemolysin XhlA USP8_interact PF08941.10 ORY41418.1 - 0.15 11.9 1.9 0.18 11.6 1.9 1.1 1 0 0 1 1 1 0 USP8 interacting SlyX PF04102.12 ORY41418.1 - 0.27 11.9 4.6 2.1 9.0 4.6 2.1 1 1 0 1 1 1 0 SlyX DivIC PF04977.15 ORY41418.1 - 0.77 9.6 4.7 3.7 7.4 4.7 2.0 1 1 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 ORY41418.1 - 0.98 9.6 3.9 3.9 7.6 1.2 2.3 1 1 1 2 2 2 0 Basic region leucine zipper PhnG PF06754.12 ORY41422.1 - 0.96 9.4 0.0 0.96 9.4 0.0 2.4 2 0 0 2 2 2 0 Phosphonate metabolism protein PhnG G-alpha PF00503.20 ORY41511.1 - 2.2e-09 37.0 0.0 2.7e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit G-alpha PF00503.20 ORY41512.1 - 5.2e-58 196.9 0.1 6.3e-58 196.6 0.1 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY41512.1 - 1.4e-08 34.4 0.3 0.00047 19.6 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 ORY41512.1 - 0.0003 21.0 0.2 0.5 10.6 0.1 2.3 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 ORY41512.1 - 0.058 12.8 0.0 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein G-alpha PF00503.20 ORY41513.1 - 4.5e-92 308.9 4.4 7.1e-89 298.4 0.5 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Arf PF00025.21 ORY41513.1 - 9.6e-14 51.2 2.0 1.1e-09 38.0 0.3 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 ORY41513.1 - 0.00036 20.7 0.2 0.85 9.8 0.0 2.8 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 ORY41513.1 - 0.0065 15.9 6.6 0.0084 15.5 0.3 2.8 2 1 1 3 3 3 1 Gtr1/RagA G protein conserved region TniB PF05621.11 ORY41513.1 - 0.009 15.4 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein DAP3 PF10236.9 ORY41513.1 - 0.052 12.7 1.2 0.88 8.7 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 GTP_EFTU PF00009.27 ORY41513.1 - 0.054 13.0 0.9 3.8 7.0 0.6 3.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Ofd1_CTDD PF10637.9 ORY41514.1 - 1.3e-66 224.6 0.0 8.1e-63 212.1 0.0 2.4 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 ORY41514.1 - 4.5e-28 97.8 0.0 9.2e-28 96.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 ORY41514.1 - 1.5e-13 51.5 0.0 3.5e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SMC_N PF02463.19 ORY41516.1 - 1.4e-27 96.6 0.0 2.7e-27 95.6 0.0 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORY41516.1 - 3.9e-11 43.8 19.7 3.9e-11 43.8 19.7 5.8 3 2 0 3 3 3 1 AAA domain AAA_15 PF13175.6 ORY41516.1 - 1.6e-07 31.4 0.2 1.6e-07 31.4 0.2 3.8 3 2 1 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 ORY41516.1 - 0.0028 17.4 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_hinge PF06470.13 ORY41516.1 - 0.0066 16.7 0.0 0.046 14.0 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain UvrA_DNA-bind PF17755.1 ORY41516.1 - 0.0082 16.5 0.6 0.9 9.9 0.0 3.0 2 0 0 2 2 2 1 UvrA DNA-binding domain Phage_int_SAM_2 PF12834.7 ORY41516.1 - 0.79 10.5 5.5 1.6 9.5 2.1 3.5 3 0 0 3 3 3 0 Phage integrase, N-terminal AAA_21 PF13304.6 ORY41516.1 - 8.1 6.1 14.5 0.32 10.8 0.9 3.7 4 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Cyclin PF08613.11 ORY41517.1 - 0.0067 16.8 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY41517.1 - 0.015 15.1 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain IQ PF00612.27 ORY41518.1 - 6.2e-11 41.1 0.8 0.00028 20.4 0.1 2.5 2 0 0 2 2 2 2 IQ calmodulin-binding motif Feld-I_B PF09252.10 ORY41518.1 - 0.14 12.1 0.9 20 5.3 0.0 2.5 2 0 0 2 2 2 0 Allergen Fel d I-B chain SNF2_assoc PF08455.10 ORY41522.1 - 0.038 13.0 2.1 0.059 12.4 2.1 1.2 1 0 0 1 1 1 0 Bacterial SNF2 helicase associated Ank_2 PF12796.7 ORY41523.1 - 6.5e-18 65.1 0.2 0.00018 22.0 0.0 4.5 2 1 0 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY41523.1 - 2.4e-08 34.1 3.1 0.0067 16.7 0.0 5.0 3 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY41523.1 - 1.3e-07 32.0 3.8 0.79 10.4 0.0 5.8 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY41523.1 - 2.4e-06 27.5 4.9 45 5.1 0.0 8.5 8 1 1 9 9 9 0 Ankyrin repeat F-box PF00646.33 ORY41523.1 - 0.00019 21.2 0.1 0.00055 19.8 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY41523.1 - 0.00023 21.0 0.3 0.00054 19.8 0.3 1.6 1 0 0 1 1 1 1 F-box-like Ank PF00023.30 ORY41523.1 - 0.00061 20.1 6.4 7.6 7.2 0.1 6.1 5 2 1 6 6 6 1 Ankyrin repeat Ank_2 PF12796.7 ORY41524.1 - 2.7e-18 66.3 3.9 9.3e-08 32.6 0.0 4.4 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY41524.1 - 3.5e-10 40.2 1.9 0.23 12.1 0.0 5.0 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY41524.1 - 7.8e-09 35.6 3.8 0.029 14.7 0.0 5.9 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY41524.1 - 6e-05 23.1 5.6 3.9 8.4 0.0 6.6 6 1 1 7 7 7 1 Ankyrin repeat Ank PF00023.30 ORY41524.1 - 0.6 10.7 10.3 6.3 7.4 0.4 6.1 4 2 1 5 5 5 0 Ankyrin repeat Gly_transf_sug PF04488.15 ORY41526.1 - 9.4e-07 29.4 0.1 3.3e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 ORY41526.1 - 0.0047 16.4 0.3 0.0079 15.6 0.2 1.4 1 1 0 1 1 1 1 Capsular polysaccharide synthesis protein LRR_8 PF13855.6 ORY41527.1 - 2.8e-17 62.2 25.0 4.6e-07 29.5 5.4 5.3 4 1 1 6 6 6 5 Leucine rich repeat LRR_1 PF00560.33 ORY41527.1 - 1.4e-11 43.2 24.7 1.2 9.9 0.2 8.5 9 0 0 9 9 9 6 Leucine Rich Repeat LRR_4 PF12799.7 ORY41527.1 - 1.1e-09 38.4 31.3 0.0078 16.6 5.4 5.5 2 2 1 5 5 5 4 Leucine Rich repeats (2 copies) Spo7_2_N PF15407.6 ORY41527.1 - 0.083 12.5 0.0 1.7 8.3 0.0 3.0 3 0 0 3 3 3 0 Sporulation protein family 7 LRR_6 PF13516.6 ORY41527.1 - 0.6 10.3 0.1 0.6 10.3 0.1 6.1 8 0 0 8 8 8 0 Leucine Rich repeat RTT107_BRCT_5 PF16770.5 ORY41529.1 - 1.2e-10 41.1 0.0 2.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 ORY41529.1 - 0.0033 17.8 0.0 0.43 11.0 0.0 2.1 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 ORY41529.1 - 0.025 15.0 0.1 0.23 11.9 0.1 2.0 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Ank_2 PF12796.7 ORY41530.1 - 1.6e-21 76.6 4.3 1e-06 29.2 0.0 4.6 1 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY41530.1 - 5.2e-11 42.8 8.4 0.069 13.7 0.1 6.4 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY41530.1 - 5.1e-08 32.6 8.0 0.97 10.2 0.0 8.2 9 1 1 10 10 10 3 Ankyrin repeat Ank_5 PF13857.6 ORY41530.1 - 1.5e-07 31.6 5.7 0.005 17.1 0.1 6.7 5 2 3 8 8 8 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY41530.1 - 2.3e-06 27.8 7.9 3.4 8.3 0.0 6.2 5 1 1 6 6 6 4 Ankyrin repeat DUF3447 PF11929.8 ORY41530.1 - 0.00067 19.6 0.6 17 5.5 0.0 4.5 4 0 0 4 4 4 1 Domain of unknown function (DUF3447) F-box PF00646.33 ORY41530.1 - 0.091 12.7 1.6 0.25 11.3 1.6 1.8 1 0 0 1 1 1 0 F-box domain VRP1 PF03538.14 ORY41530.1 - 0.11 11.9 0.6 0.58 9.5 0.2 2.0 2 0 0 2 2 2 0 Salmonella virulence plasmid 28.1kDa A protein Pkinase PF00069.25 ORY41531.1 - 0.0066 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.20 ORY41531.1 - 0.17 11.4 0.3 0.33 10.5 0.3 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-CW PF07496.15 ORY41532.1 - 0.0068 16.4 1.4 0.015 15.3 0.2 2.2 2 0 0 2 2 2 1 CW-type Zinc Finger Ank_2 PF12796.7 ORY41533.1 - 2.6e-19 69.6 4.1 1.1e-05 26.0 0.0 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY41533.1 - 1.7e-09 37.7 1.9 0.022 15.1 0.0 4.7 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY41533.1 - 5.3e-09 36.4 3.5 0.14 12.8 0.4 4.5 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY41533.1 - 1.8e-07 30.9 3.1 14 6.6 0.0 6.3 6 1 1 7 7 7 3 Ankyrin repeat Ank PF00023.30 ORY41533.1 - 3.1e-06 27.4 4.2 2 9.0 0.0 5.8 4 2 1 5 5 5 1 Ankyrin repeat MiaE_2 PF13794.6 ORY41533.1 - 0.18 11.5 0.1 1.2 8.8 0.0 2.3 2 1 1 3 3 3 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like SNF2_assoc PF08455.10 ORY41536.1 - 0.034 13.2 2.1 0.052 12.6 2.1 1.2 1 0 0 1 1 1 0 Bacterial SNF2 helicase associated Helitron_like_N PF14214.6 ORY41536.1 - 0.052 13.8 0.5 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus DUF3045 PF11243.8 ORY41537.1 - 0.063 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) RNase_T PF00929.24 ORY41538.1 - 3.2e-30 105.8 0.0 4e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 ORY41538.1 - 0.0012 18.8 0.0 0.0029 17.6 0.0 1.6 2 0 0 2 2 2 1 3' exoribonuclease, RNase T-like RepB-RCR_reg PF10723.9 ORY41538.1 - 0.099 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Replication regulatory protein RepB Ribosomal_S13 PF00416.22 ORY41539.1 - 2e-53 180.2 1.5 2.4e-53 179.9 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 HHH_6 PF14579.6 ORY41539.1 - 0.069 13.4 0.4 0.21 11.9 0.1 2.0 2 1 0 2 2 2 0 Helix-hairpin-helix motif zf-C2H2 PF00096.26 ORY41540.1 - 4.1e-14 52.1 26.9 0.0095 16.3 1.1 5.4 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY41540.1 - 1.5e-07 31.6 25.8 0.098 13.5 2.4 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY41540.1 - 0.00097 19.1 2.0 0.00097 19.1 2.0 4.9 5 0 0 5 5 5 1 C2H2-type zinc finger zf-met PF12874.7 ORY41540.1 - 0.0017 18.7 10.1 2.7 8.5 0.7 4.8 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 ORY41540.1 - 0.0025 18.1 1.6 0.0025 18.1 1.6 2.8 3 1 1 4 4 4 1 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 ORY41540.1 - 0.0034 17.7 0.6 0.0034 17.7 0.6 4.7 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY41540.1 - 0.091 13.1 10.7 0.37 11.1 0.9 4.0 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding Ig_3 PF13927.6 ORY41540.1 - 0.093 13.3 0.5 0.28 11.8 0.1 2.0 2 0 0 2 2 2 0 Immunoglobulin domain zf-C2H2_11 PF16622.5 ORY41540.1 - 0.097 12.4 10.2 2.3 8.1 0.5 4.1 4 0 0 4 4 4 0 zinc-finger C2H2-type PHD PF00628.29 ORY41541.1 - 0.0002 21.2 11.5 0.00035 20.4 11.5 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORY41541.1 - 6.2 6.5 13.5 0.22 11.1 7.5 1.8 2 0 0 2 2 2 0 PHD-finger OSR1_C PF12202.8 ORY41542.1 - 0.17 12.1 0.4 0.39 11.0 0.4 1.6 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C-terminal domain CCDC53 PF10152.9 ORY41543.1 - 0.071 13.5 0.4 0.087 13.2 0.4 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex TFIIA PF03153.13 ORY41543.1 - 4.1 7.3 7.6 4.7 7.1 7.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAP_assoc PF03828.19 ORY41544.1 - 8.2e-12 45.2 0.0 5.5e-11 42.5 0.0 2.3 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 ORY41544.1 - 1e-06 29.0 0.0 2.6e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 ORY41544.1 - 0.18 11.9 0.0 0.43 10.7 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase AF-4 PF05110.13 ORY41544.1 - 0.88 7.6 20.9 1.1 7.2 20.9 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein HET PF06985.11 ORY41545.1 - 0.0017 18.7 0.0 0.0028 18.0 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Nitrate_red_gam PF02665.14 ORY41545.1 - 0.2 11.2 0.1 0.3 10.6 0.1 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit bZIP_1 PF00170.21 ORY41547.1 - 1.1e-08 35.1 9.3 1.3e-06 28.4 3.6 2.2 2 0 0 2 2 2 2 bZIP transcription factor TSC22 PF01166.18 ORY41547.1 - 4e-05 23.8 1.7 0.0016 18.7 0.2 2.5 2 0 0 2 2 2 1 TSC-22/dip/bun family Mt_ATP-synt_D PF05873.12 ORY41547.1 - 0.0033 17.3 0.2 0.053 13.4 0.0 2.2 2 0 0 2 2 2 1 ATP synthase D chain, mitochondrial (ATP5H) ABC_tran_CTD PF16326.5 ORY41547.1 - 0.0069 16.6 3.4 1.8 8.9 0.2 2.4 2 0 0 2 2 2 2 ABC transporter C-terminal domain GOLGA2L5 PF15070.6 ORY41547.1 - 0.0071 15.1 1.2 0.0088 14.8 1.2 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 zf-C2H2_2 PF12756.7 ORY41547.1 - 0.0096 16.2 2.0 0.55 10.6 0.2 2.1 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) HOOK PF05622.12 ORY41547.1 - 0.013 13.7 0.9 0.015 13.4 0.9 1.1 1 0 0 1 1 1 0 HOOK protein UPF0242 PF06785.11 ORY41547.1 - 0.014 15.5 1.6 3.3 7.8 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF390 PF04094.14 ORY41547.1 - 0.026 12.9 3.1 0.034 12.4 3.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF390) BRE1 PF08647.11 ORY41547.1 - 0.028 14.5 0.6 0.048 13.7 0.1 1.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase EzrA PF06160.12 ORY41547.1 - 0.032 12.4 0.2 1.9 6.5 0.0 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA YabA PF06156.13 ORY41547.1 - 0.034 14.8 1.2 0.051 14.2 0.3 1.7 2 0 0 2 2 2 0 Initiation control protein YabA DUF16 PF01519.16 ORY41547.1 - 0.05 14.1 0.1 0.075 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 Ax_dynein_light PF10211.9 ORY41547.1 - 0.053 13.5 3.0 0.2 11.6 3.0 1.8 1 1 0 1 1 1 0 Axonemal dynein light chain K-box PF01486.17 ORY41547.1 - 0.074 13.2 0.4 0.074 13.2 0.4 1.8 2 0 0 2 2 2 0 K-box region FlxA PF14282.6 ORY41547.1 - 0.075 13.0 0.6 0.15 12.0 0.4 1.7 1 1 0 1 1 1 0 FlxA-like protein ZapB PF06005.12 ORY41547.1 - 0.077 13.4 3.2 0.13 12.7 0.1 2.4 2 1 0 2 2 2 0 Cell division protein ZapB zf-C4pol PF14260.6 ORY41547.1 - 0.082 13.4 5.4 0.13 12.7 4.3 1.8 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Fmp27_WPPW PF10359.9 ORY41547.1 - 0.1 11.4 2.7 0.12 11.2 2.7 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain GAS PF13851.6 ORY41547.1 - 0.1 11.9 1.9 0.088 12.1 0.7 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Shugoshin_N PF07558.11 ORY41547.1 - 0.14 12.1 4.2 1.1 9.2 0.6 2.3 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region bZIP_2 PF07716.15 ORY41547.1 - 0.15 12.1 12.1 1.8 8.7 0.5 2.3 2 0 0 2 2 2 0 Basic region leucine zipper TMF_TATA_bd PF12325.8 ORY41547.1 - 0.19 12.0 3.1 0.75 10.0 0.6 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4618 PF15397.6 ORY41547.1 - 0.28 10.6 4.3 1.8 7.9 0.5 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) DUF2076 PF09849.9 ORY41547.1 - 1.7 8.6 8.7 2 8.4 4.7 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) bZIP_Maf PF03131.17 ORY41547.1 - 4.3 7.9 11.3 6.5 7.4 4.8 2.3 1 1 1 2 2 2 0 bZIP Maf transcription factor bZIP_1 PF00170.21 ORY41549.1 - 2e-06 27.8 1.3 2e-06 27.8 1.3 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORY41549.1 - 0.063 13.4 0.9 0.063 13.4 0.9 2.0 2 0 0 2 2 2 0 Basic region leucine zipper PKcGMP_CC PF16808.5 ORY41549.1 - 0.84 9.5 3.4 0.64 9.9 0.9 1.9 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF627 PF04781.12 ORY41550.1 - 0.092 12.8 0.3 0.61 10.1 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF627) bZIP_1 PF00170.21 ORY41552.1 - 4e-12 46.0 9.3 4.8e-08 33.0 5.1 2.4 2 0 0 2 2 2 2 bZIP transcription factor Laminin_I PF06008.14 ORY41552.1 - 2.2e-05 24.3 0.4 2.2e-05 24.3 0.4 1.7 1 1 1 2 2 2 1 Laminin Domain I ABC_tran_CTD PF16326.5 ORY41552.1 - 0.00013 22.2 3.5 0.00019 21.6 1.3 2.1 1 1 1 2 2 2 1 ABC transporter C-terminal domain bZIP_2 PF07716.15 ORY41552.1 - 0.00035 20.6 18.5 0.04 14.0 10.3 2.6 2 2 0 2 2 2 2 Basic region leucine zipper HOOK PF05622.12 ORY41552.1 - 0.00092 17.5 2.0 0.0011 17.3 2.0 1.1 1 0 0 1 1 1 1 HOOK protein FapA PF03961.13 ORY41552.1 - 0.0012 17.5 0.9 0.0014 17.3 0.9 1.1 1 0 0 1 1 1 1 Flagellar Assembly Protein A ATG16 PF08614.11 ORY41552.1 - 0.0018 18.6 6.1 0.0023 18.2 6.1 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) ADIP PF11559.8 ORY41552.1 - 0.0027 17.8 4.8 0.5 10.4 0.1 2.1 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding GOLGA2L5 PF15070.6 ORY41552.1 - 0.0027 16.5 4.0 0.0034 16.1 4.0 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 Csm1_N PF18504.1 ORY41552.1 - 0.0028 18.0 3.4 0.87 10.0 1.2 2.5 2 0 0 2 2 2 1 Csm1 N-terminal domain TSC22 PF01166.18 ORY41552.1 - 0.0033 17.7 6.1 0.081 13.2 0.9 2.3 2 0 0 2 2 2 1 TSC-22/dip/bun family DivIC PF04977.15 ORY41552.1 - 0.0034 17.1 3.6 0.78 9.6 0.0 2.3 2 0 0 2 2 2 1 Septum formation initiator Fmp27_WPPW PF10359.9 ORY41552.1 - 0.0039 16.1 2.4 0.0043 16.0 2.4 1.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain HAUS-augmin3 PF14932.6 ORY41552.1 - 0.0042 16.7 2.3 0.0055 16.3 2.3 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 CREPT PF16566.5 ORY41552.1 - 0.0051 17.0 3.9 0.0064 16.7 3.9 1.1 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour DUF2730 PF10805.8 ORY41552.1 - 0.0056 16.7 0.7 2.2 8.4 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2730) SHE3 PF17078.5 ORY41552.1 - 0.0069 16.1 5.0 0.077 12.7 2.7 2.0 1 1 1 2 2 2 1 SWI5-dependent HO expression protein 3 DUF4618 PF15397.6 ORY41552.1 - 0.0072 15.8 3.1 0.21 11.0 1.3 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4618) YabA PF06156.13 ORY41552.1 - 0.012 16.3 0.6 0.3 11.7 0.0 2.2 2 0 0 2 2 2 0 Initiation control protein YabA FlaC_arch PF05377.11 ORY41552.1 - 0.014 15.7 3.1 0.64 10.5 0.2 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) V_ATPase_I PF01496.19 ORY41552.1 - 0.016 13.1 1.7 0.018 13.0 1.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nnf1 PF03980.14 ORY41552.1 - 0.016 15.5 9.4 0.097 13.1 0.4 2.2 1 1 1 2 2 2 0 Nnf1 SlyX PF04102.12 ORY41552.1 - 0.018 15.7 3.9 2.6 8.8 1.7 2.3 2 0 0 2 2 2 0 SlyX Spc24 PF08286.11 ORY41552.1 - 0.024 14.9 1.9 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 NPV_P10 PF05531.12 ORY41552.1 - 0.027 15.0 0.4 3.9 8.0 0.3 2.1 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Lzipper-MIP1 PF14389.6 ORY41552.1 - 0.027 14.8 6.2 0.11 12.9 6.2 1.9 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Spc7 PF08317.11 ORY41552.1 - 0.028 13.3 6.1 0.92 8.3 0.1 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 ORY41552.1 - 0.031 14.6 1.3 3.7 7.9 0.0 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4349 PF14257.6 ORY41552.1 - 0.035 13.5 0.9 0.053 13.0 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) PKcGMP_CC PF16808.5 ORY41552.1 - 0.043 13.7 5.8 0.1 12.4 1.5 3.0 2 2 1 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4988 PF16378.5 ORY41552.1 - 0.045 13.4 0.4 1 9.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function TPR_MLP1_2 PF07926.12 ORY41552.1 - 0.047 13.8 11.3 0.38 10.8 11.4 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein CLZ PF16526.5 ORY41552.1 - 0.047 14.0 7.0 1 9.8 0.5 2.2 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_Maf PF03131.17 ORY41552.1 - 0.049 14.2 7.7 1.1 9.8 4.2 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor SKA2 PF16740.5 ORY41552.1 - 0.058 13.2 2.5 0.69 9.7 1.8 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF3138 PF11336.8 ORY41552.1 - 0.058 12.0 0.1 0.069 11.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4200 PF13863.6 ORY41552.1 - 0.063 13.7 6.0 1.1 9.7 3.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) BST2 PF16716.5 ORY41552.1 - 0.067 13.8 5.6 4.1 8.1 2.1 2.2 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Swi5 PF07061.11 ORY41552.1 - 0.076 13.1 3.4 3 8.0 0.9 2.3 1 1 1 2 2 2 0 Swi5 GIT_CC PF16559.5 ORY41552.1 - 0.08 12.8 2.1 0.29 11.0 0.2 2.4 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4635 PF15466.6 ORY41552.1 - 0.083 12.4 0.9 0.14 11.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) ZapB PF06005.12 ORY41552.1 - 0.091 13.2 0.2 0.091 13.2 0.2 2.2 2 0 0 2 2 2 0 Cell division protein ZapB GrpE PF01025.19 ORY41552.1 - 0.11 12.2 8.5 6.9 6.3 8.5 2.1 1 1 0 1 1 1 0 GrpE DUF2968 PF11180.8 ORY41552.1 - 0.11 12.2 4.0 0.14 11.7 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DHR10 PF18595.1 ORY41552.1 - 0.12 12.4 11.0 1.8 8.6 4.3 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain CENP-F_leu_zip PF10473.9 ORY41552.1 - 0.12 12.4 7.9 0.56 10.2 8.0 1.7 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.20 ORY41552.1 - 0.13 12.2 5.0 2.9 7.9 2.0 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF4407 PF14362.6 ORY41552.1 - 0.14 11.5 5.4 0.63 9.3 5.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 ORY41552.1 - 0.16 12.4 7.3 0.6 10.5 7.0 1.8 1 1 1 2 2 2 0 Fez1 Viral_P18 PF04521.13 ORY41552.1 - 0.16 11.7 0.9 0.27 11.0 0.5 1.5 1 1 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein CENP-H PF05837.12 ORY41552.1 - 0.17 12.3 6.2 0.56 10.6 0.1 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) TolA_bind_tri PF16331.5 ORY41552.1 - 0.17 12.0 5.0 2 8.5 4.3 2.3 1 1 0 1 1 1 0 TolA binding protein trimerisation DUF4140 PF13600.6 ORY41552.1 - 0.17 12.3 8.8 1.6 9.2 0.2 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Golgin_A5 PF09787.9 ORY41552.1 - 0.19 11.2 7.9 0.43 10.0 7.9 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 5 Tropomyosin_1 PF12718.7 ORY41552.1 - 0.21 11.7 8.8 0.38 10.9 8.8 1.3 1 1 0 1 1 1 0 Tropomyosin like MAD PF05557.13 ORY41552.1 - 0.22 9.9 8.5 0.91 7.8 8.6 1.7 1 1 0 1 1 1 0 Mitotic checkpoint protein TMF_TATA_bd PF12325.8 ORY41552.1 - 0.28 11.4 7.5 0.53 10.5 0.4 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding GAS PF13851.6 ORY41552.1 - 0.37 10.1 8.1 2.2 7.6 8.1 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 ORY41552.1 - 0.38 10.8 7.4 1.6 8.8 7.3 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HalX PF08663.10 ORY41552.1 - 0.39 11.1 8.0 3.3 8.1 1.5 2.9 1 1 1 2 2 2 0 HalX domain FlxA PF14282.6 ORY41552.1 - 0.41 10.7 7.8 2 8.4 6.0 2.2 1 1 1 2 2 2 0 FlxA-like protein BRI3BP PF14965.6 ORY41552.1 - 0.45 10.0 5.0 6.6 6.2 0.8 2.1 2 0 0 2 2 2 0 Negative regulator of p53/TP53 DMPK_coil PF08826.10 ORY41552.1 - 0.5 10.5 10.1 2.1 8.5 4.0 2.2 2 0 0 2 2 2 0 DMPK coiled coil domain like MCC-bdg_PDZ PF10506.9 ORY41552.1 - 0.66 10.0 5.6 1.8 8.6 0.8 2.4 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Atg14 PF10186.9 ORY41552.1 - 0.76 8.8 9.4 14 4.7 9.4 2.0 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Uso1_p115_C PF04871.13 ORY41552.1 - 0.77 10.1 9.1 0.86 10.0 8.1 1.6 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1690 PF07956.11 ORY41552.1 - 0.79 10.1 7.0 1 9.8 7.0 1.1 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) EMP24_GP25L PF01105.24 ORY41552.1 - 0.89 9.5 3.6 7.1 6.5 3.6 2.0 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD HIP1_clath_bdg PF16515.5 ORY41552.1 - 0.91 10.2 9.5 3.7 8.2 9.6 1.8 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 PspB PF06667.12 ORY41552.1 - 0.92 9.6 4.6 17 5.6 0.2 2.6 2 1 1 3 3 2 0 Phage shock protein B LPP PF04728.13 ORY41552.1 - 0.94 9.9 9.1 2 8.9 0.1 2.7 2 1 1 3 3 2 0 Lipoprotein leucine-zipper DUF1003 PF06210.11 ORY41552.1 - 0.94 9.6 3.0 3.6 7.7 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) HALZ PF02183.18 ORY41552.1 - 1.1 9.5 8.9 0.37 11.0 1.5 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper Cep57_CLD_2 PF14197.6 ORY41552.1 - 1.5 9.0 12.4 4.5 7.4 0.1 3.3 2 2 0 3 3 3 0 Centrosome localisation domain of PPC89 APG6_N PF17675.1 ORY41552.1 - 1.6 9.3 11.7 1.3 9.6 0.4 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF641 PF04859.12 ORY41552.1 - 1.7 9.0 7.4 15 5.9 7.4 2.0 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Miff PF05644.11 ORY41552.1 - 1.8 8.1 9.6 1.4 8.5 0.7 1.9 1 1 1 2 2 2 0 Mitochondrial and peroxisomal fission factor Mff TMF_DNA_bd PF12329.8 ORY41552.1 - 1.9 8.5 9.9 3.2 7.8 1.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF5320 PF17253.2 ORY41552.1 - 2.2 9.4 5.8 8.6 7.5 0.2 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5320) NYD-SP28_assoc PF14775.6 ORY41552.1 - 9.7 6.4 7.2 5.5 7.2 0.6 2.3 2 0 0 2 2 2 0 Sperm tail C-terminal domain bZIP_1 PF00170.21 ORY41554.1 - 1.4e-05 25.1 9.3 1.4e-05 25.1 9.3 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 ORY41554.1 - 0.00077 19.9 10.4 0.00077 19.9 10.4 3.4 3 1 1 4 4 4 1 bZIP Maf transcription factor bZIP_2 PF07716.15 ORY41554.1 - 0.0018 18.3 9.7 0.0018 18.3 9.7 2.0 3 0 0 3 3 3 1 Basic region leucine zipper Sec34 PF04136.15 ORY41554.1 - 1.4 8.8 10.5 0.98 9.3 4.9 2.2 2 0 0 2 2 2 0 Sec34-like family SHE3 PF17078.5 ORY41554.1 - 8.5 6.0 13.6 0.18 11.5 6.3 1.9 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 bZIP_1 PF00170.21 ORY41555.1 - 1.6e-10 40.9 9.0 9.9e-08 32.0 4.3 2.2 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 ORY41555.1 - 0.0075 16.3 9.3 0.038 14.1 2.3 2.3 2 0 0 2 2 2 2 Basic region leucine zipper TSC22 PF01166.18 ORY41555.1 - 0.042 14.2 1.3 0.15 12.4 0.4 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family Shugoshin_N PF07558.11 ORY41555.1 - 0.1 12.5 4.2 0.13 12.2 0.8 2.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region PKcGMP_CC PF16808.5 ORY41555.1 - 1.9 8.4 7.5 0.37 10.7 0.6 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TSC22 PF01166.18 ORY41556.1 - 0.00034 20.8 0.2 0.0006 20.1 0.2 1.4 1 0 0 1 1 1 1 TSC-22/dip/bun family bZIP_1 PF00170.21 ORY41556.1 - 0.023 14.8 1.4 0.032 14.3 1.4 1.1 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 ORY41556.1 - 0.042 13.9 3.2 0.061 13.4 3.2 1.1 1 0 0 1 1 1 0 Basic region leucine zipper M PF02370.16 ORY41556.1 - 0.21 12.3 3.9 0.31 11.7 3.9 1.3 1 0 0 1 1 1 0 M protein repeat WD40_alt PF14077.6 ORY41556.1 - 0.44 10.4 1.9 0.63 10.0 1.9 1.1 1 0 0 1 1 1 0 Alternative WD40 repeat motif PKcGMP_CC PF16808.5 ORY41556.1 - 2.7 7.9 5.3 3.6 7.5 5.3 1.1 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase bZIP_1 PF00170.21 ORY41557.1 - 1e-06 28.7 13.4 3.3e-05 23.9 6.3 3.1 3 0 0 3 3 3 2 bZIP transcription factor TSC22 PF01166.18 ORY41557.1 - 0.022 15.1 3.6 0.022 15.1 0.3 2.7 3 1 1 4 4 4 0 TSC-22/dip/bun family bZIP_2 PF07716.15 ORY41557.1 - 0.18 11.9 12.7 3.6 7.7 7.6 2.7 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 ORY41558.1 - 3.1e-08 33.6 34.9 0.0004 20.4 10.6 4.8 4 1 0 4 4 4 3 bZIP transcription factor TSC22 PF01166.18 ORY41558.1 - 7.5e-05 23.0 5.1 0.14 12.5 0.3 2.9 2 0 0 2 2 2 2 TSC-22/dip/bun family Mito_fiss_reg PF05308.11 ORY41558.1 - 0.27 11.3 8.0 1.9 8.5 4.2 2.5 2 0 0 2 2 2 0 Mitochondrial fission regulator MerR_2 PF13591.6 ORY41558.1 - 0.49 10.3 11.2 3.1 7.7 1.3 3.9 3 0 0 3 3 3 0 MerR HTH family regulatory protein OrfB_IS605 PF01385.19 ORY41558.1 - 1.3 9.2 8.1 3.4 7.9 0.8 2.7 2 0 0 2 2 2 0 Probable transposase bZIP_1 PF00170.21 ORY41559.1 - 1.2e-08 34.9 32.1 0.00072 19.6 9.3 4.5 4 0 0 4 4 4 3 bZIP transcription factor Mvb12 PF09452.10 ORY41559.1 - 0.0047 17.3 0.8 0.094 13.2 0.1 3.1 2 0 0 2 2 2 1 ESCRT-I subunit Mvb12 DUF2937 PF11157.8 ORY41559.1 - 0.037 13.7 1.0 0.12 12.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) TSC22 PF01166.18 ORY41559.1 - 0.42 11.0 7.6 0.21 11.9 0.7 3.4 3 0 0 3 3 3 0 TSC-22/dip/bun family bZIP_2 PF07716.15 ORY41559.1 - 0.98 9.5 39.4 0.55 10.3 8.8 4.5 4 0 0 4 4 4 0 Basic region leucine zipper Mt_ATP-synt_B PF05405.14 ORY41559.1 - 1.8 8.1 7.3 0.5 10.0 0.1 3.1 3 0 0 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) OrfB_IS605 PF01385.19 ORY41559.1 - 6.4 7.0 7.7 17 5.7 0.2 2.7 2 0 0 2 2 2 0 Probable transposase SNAPc19 PF15497.6 ORY41559.1 - 8.2 7.0 10.3 2.9 8.4 3.1 3.6 3 1 0 3 3 3 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 DED PF01335.21 ORY41560.1 - 0.035 14.4 0.3 7.2 7.0 0.1 2.8 2 1 0 2 2 2 0 Death effector domain Cnd3 PF12719.7 ORY41561.1 - 1.4e-60 205.0 7.6 3.3e-59 200.5 1.0 3.2 4 0 0 4 4 4 2 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 ORY41561.1 - 4.3e-08 33.4 0.3 3e-05 24.3 0.0 4.1 2 1 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 ORY41561.1 - 0.044 14.3 1.1 0.94 10.1 0.0 4.0 5 0 0 5 5 5 0 HEAT-like repeat HEAT PF02985.22 ORY41561.1 - 0.046 14.0 12.1 12 6.4 0.1 6.7 8 0 0 8 8 8 0 HEAT repeat Gemin6 PF06372.12 ORY41561.1 - 0.15 11.6 0.0 8.8 5.8 0.0 2.7 3 0 0 3 3 3 0 Gemin6 protein zf-like PF04071.12 ORY41561.1 - 0.16 11.9 0.0 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 Cysteine-rich small domain API5 PF05918.11 ORY41561.1 - 0.25 10.1 2.1 0.62 8.8 0.1 2.3 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) bZIP_1 PF00170.21 ORY41562.1 - 2.4e-05 24.3 6.3 4.7e-05 23.4 6.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY41562.1 - 0.0062 16.6 6.2 0.0095 16.0 6.2 1.3 1 0 0 1 1 1 1 Basic region leucine zipper CENP-R PF06729.12 ORY41562.1 - 0.077 12.9 6.1 0.053 13.4 4.9 1.3 1 1 0 1 1 1 0 Kinetochore component, CENP-R ASD2 PF08687.11 ORY41562.1 - 0.099 12.2 5.4 0.12 11.9 5.4 1.0 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 CENP-U PF13097.6 ORY41562.1 - 0.26 11.2 8.8 0.32 10.9 8.8 1.1 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit DUF3292 PF11696.8 ORY41562.1 - 0.65 8.3 6.1 0.68 8.2 6.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) CDC45 PF02724.14 ORY41562.1 - 1.7 6.8 9.5 1.9 6.7 9.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Apt1 PF10351.9 ORY41562.1 - 3.4 6.4 9.9 4.2 6.1 9.9 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Zip PF02535.22 ORY41562.1 - 9.7 5.3 6.7 9.9 5.3 6.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter LPMO_10 PF03067.15 ORY41563.1 - 0.00022 22.0 0.2 0.00022 22.0 0.2 2.6 2 1 1 3 3 3 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading 7tm_3 PF00003.22 ORY41565.1 - 1.8e-16 60.6 12.5 2.7e-16 60.0 12.5 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF4131 PF13567.6 ORY41565.1 - 0.2 11.3 5.9 0.45 10.1 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) TSC22 PF01166.18 ORY41566.1 - 0.026 14.8 0.8 0.085 13.2 0.8 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family Sec2p PF06428.11 ORY41566.1 - 1.8 8.6 6.0 2.3 8.3 0.1 3.0 4 0 0 4 4 4 0 GDP/GTP exchange factor Sec2p bZIP_2 PF07716.15 ORY41566.1 - 4.1 7.6 6.2 0.81 9.8 1.7 2.1 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_1 PF00170.21 ORY41567.1 - 5.2e-07 29.7 15.9 2.6e-05 24.2 10.2 2.5 2 0 0 2 2 2 2 bZIP transcription factor TSC22 PF01166.18 ORY41567.1 - 0.0088 16.3 0.4 0.026 14.8 0.4 1.8 1 0 0 1 1 1 1 TSC-22/dip/bun family bZIP_2 PF07716.15 ORY41567.1 - 0.3 11.2 19.6 0.28 11.3 1.0 2.3 2 0 0 2 2 2 0 Basic region leucine zipper PKcGMP_CC PF16808.5 ORY41567.1 - 0.67 9.9 5.7 0.35 10.8 0.3 2.4 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase bZIP_1 PF00170.21 ORY41568.1 - 1.4e-05 25.1 15.4 0.001 19.1 5.0 2.5 2 0 0 2 2 2 2 bZIP transcription factor PKcGMP_CC PF16808.5 ORY41568.1 - 0.062 13.2 1.8 0.062 13.2 1.8 2.1 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase bZIP_1 PF00170.21 ORY41569.1 - 6.1e-05 23.0 5.0 0.00011 22.2 0.4 2.9 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 ORY41569.1 - 0.0001 22.3 1.8 0.0028 17.7 0.2 2.7 2 0 0 2 2 2 1 Basic region leucine zipper DUF848 PF05852.11 ORY41569.1 - 0.021 14.9 0.1 0.061 13.4 0.1 1.8 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) bZIP_1 PF00170.21 ORY41570.1 - 1.4e-10 41.1 16.0 8.2e-07 29.0 1.3 2.3 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 ORY41570.1 - 6e-08 32.6 10.4 2.8e-05 24.1 0.4 2.3 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.17 ORY41570.1 - 0.0095 16.4 13.7 0.026 15.0 0.3 2.3 2 0 0 2 2 2 1 bZIP Maf transcription factor DUF2630 PF10944.8 ORY41570.1 - 0.013 16.0 4.4 0.013 16.0 4.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2630) Miga PF10265.9 ORY41570.1 - 0.15 11.0 1.5 0.21 10.5 1.5 1.1 1 0 0 1 1 1 0 Mitoguardin LCD1 PF09798.9 ORY41570.1 - 0.42 9.1 5.2 0.54 8.7 5.2 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein BLOC1_2 PF10046.9 ORY41570.1 - 0.58 10.5 4.0 8.1 6.8 1.7 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 ORY41570.1 - 0.92 10.2 9.2 6 7.6 0.2 2.8 2 1 0 2 2 2 0 SlyX POX PF07526.11 ORY41570.1 - 3.1 8.4 10.0 0.48 11.0 3.8 2.1 1 1 1 2 2 2 0 Associated with HOX Filament PF00038.21 ORY41571.1 - 0.99 8.9 94.9 0.53 9.8 9.1 6.3 2 2 3 5 5 5 0 Intermediate filament protein DUF211 PF02680.14 ORY41571.1 - 1.3 9.2 9.3 7.1 6.9 0.0 4.3 5 0 0 5 5 5 0 Uncharacterized ArCR, COG1888 bZIP_2 PF07716.15 ORY41572.1 - 0.0042 17.1 1.7 0.0063 16.6 1.7 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ORY41572.1 - 0.024 14.7 0.3 0.034 14.2 0.3 1.2 1 0 0 1 1 1 0 bZIP transcription factor GIT_CC PF16559.5 ORY41572.1 - 0.073 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor TSC22 PF01166.18 ORY41572.1 - 0.088 13.1 0.2 0.14 12.5 0.2 1.2 1 0 0 1 1 1 0 TSC-22/dip/bun family Shugoshin_N PF07558.11 ORY41572.1 - 0.18 11.7 0.5 0.26 11.2 0.5 1.2 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region DUF3375 PF11855.8 ORY41572.1 - 0.19 10.6 0.8 0.32 9.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) DUF1192 PF06698.11 ORY41572.1 - 0.31 11.1 0.9 0.54 10.4 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) bZIP_1 PF00170.21 ORY41573.1 - 8.2e-09 35.4 17.5 7.9e-06 25.9 6.6 2.2 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 ORY41573.1 - 0.032 14.3 18.8 0.22 11.6 4.2 2.4 1 1 1 2 2 2 0 Basic region leucine zipper DUF3573 PF12097.8 ORY41573.1 - 0.09 11.6 0.1 0.14 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) PKcGMP_CC PF16808.5 ORY41573.1 - 0.15 12.0 8.6 0.32 10.9 0.0 3.0 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ABC_tran_CTD PF16326.5 ORY41573.1 - 0.15 12.3 2.7 0.29 11.4 2.7 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF1690 PF07956.11 ORY41573.1 - 0.99 9.8 9.7 1.6 9.2 9.7 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) TSC22 PF01166.18 ORY41573.1 - 2.8 8.3 8.3 0.19 12.1 1.3 2.3 2 1 1 3 3 3 0 TSC-22/dip/bun family bZIP_1 PF00170.21 ORY41574.1 - 2.4e-10 40.3 12.7 2.1e-06 27.7 7.5 2.2 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 ORY41574.1 - 0.012 15.7 15.1 0.13 12.3 0.4 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Shugoshin_N PF07558.11 ORY41574.1 - 0.05 13.5 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region PKcGMP_CC PF16808.5 ORY41574.1 - 0.33 10.8 0.1 0.33 10.8 0.1 2.8 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1690 PF07956.11 ORY41574.1 - 0.4 11.1 5.2 0.7 10.3 5.2 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) bZIP_Maf PF03131.17 ORY41574.1 - 7.6 7.1 11.4 8.2 7.0 9.6 1.8 1 1 1 2 2 2 0 bZIP Maf transcription factor bZIP_1 PF00170.21 ORY41575.1 - 1.7e-10 40.8 11.8 1.2e-07 31.7 5.6 2.5 1 1 1 2 2 2 2 bZIP transcription factor bZIP_Maf PF03131.17 ORY41575.1 - 0.0088 16.5 12.8 0.037 14.5 12.4 2.3 1 1 0 1 1 1 1 bZIP Maf transcription factor TSC22 PF01166.18 ORY41575.1 - 0.014 15.7 1.9 2.6 8.4 0.2 3.1 2 1 1 3 3 3 0 TSC-22/dip/bun family bZIP_2 PF07716.15 ORY41575.1 - 0.016 15.3 19.1 0.028 14.5 5.4 2.7 2 1 1 3 3 3 0 Basic region leucine zipper Shugoshin_N PF07558.11 ORY41575.1 - 0.018 14.9 3.0 0.066 13.1 0.4 2.7 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region aGPT-Pplase1 PF18723.1 ORY41576.1 - 1.2e-24 87.3 0.0 5.4e-24 85.1 0.0 1.9 1 1 0 1 1 1 1 alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 1 FA_desaturase PF00487.24 ORY41576.1 - 0.06 13.2 0.5 0.094 12.5 0.5 1.2 1 0 0 1 1 1 0 Fatty acid desaturase cNMP_binding PF00027.29 ORY41577.1 - 1.6e-16 60.1 0.0 3.1e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain TPR_2 PF07719.17 ORY41579.1 - 6.7e-33 110.1 29.6 0.0011 18.9 0.1 17.1 18 0 0 18 18 16 7 Tetratricopeptide repeat TPR_1 PF00515.28 ORY41579.1 - 1.3e-29 100.8 17.8 2.1e-05 24.1 0.0 14.4 17 0 0 17 17 15 5 Tetratricopeptide repeat TPR_8 PF13181.6 ORY41579.1 - 6.7e-25 85.2 2.7 0.0017 18.4 0.0 13.1 14 0 0 14 14 11 4 Tetratricopeptide repeat TPR_17 PF13431.6 ORY41579.1 - 3.4e-24 83.4 13.2 0.00018 21.7 0.1 12.6 13 0 0 13 13 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 ORY41579.1 - 1.5e-19 70.3 23.9 0.0011 19.4 0.0 12.0 13 2 2 15 15 12 4 Tetratricopeptide repeat TPR_12 PF13424.6 ORY41579.1 - 7.2e-18 64.7 27.5 0.0011 19.3 0.1 12.1 10 2 2 12 12 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 ORY41579.1 - 1.9e-17 62.7 7.5 0.015 15.0 0.0 12.7 13 1 1 14 14 13 2 TPR repeat TPR_14 PF13428.6 ORY41579.1 - 1.9e-17 62.4 29.7 1.4 10.0 0.0 16.6 12 4 6 19 19 15 5 Tetratricopeptide repeat TPR_16 PF13432.6 ORY41579.1 - 4e-17 62.6 26.3 0.00034 21.2 0.0 11.9 10 3 4 14 14 13 5 Tetratricopeptide repeat TPR_7 PF13176.6 ORY41579.1 - 1.7e-13 49.6 12.6 0.58 10.3 0.0 10.5 11 0 0 11 11 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY41579.1 - 4e-10 39.8 7.4 0.14 12.4 0.0 9.3 8 2 1 10 10 10 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 ORY41579.1 - 3.9e-08 33.3 5.0 0.13 12.4 0.0 6.9 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_20 PF14561.6 ORY41579.1 - 5e-08 33.2 1.2 0.012 15.9 0.0 6.2 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY41579.1 - 1e-07 32.1 21.7 14 6.6 0.0 11.0 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_15 PF13429.6 ORY41579.1 - 1.1e-05 24.8 4.1 0.087 12.0 0.0 5.5 5 1 1 6 6 6 1 Tetratricopeptide repeat Coatomer_E PF04733.14 ORY41579.1 - 0.0018 17.7 0.0 0.44 9.9 0.0 3.9 4 0 0 4 4 4 1 Coatomer epsilon subunit BTAD PF03704.17 ORY41579.1 - 0.0048 17.3 7.4 3.6 8.0 0.0 5.7 6 1 0 6 6 6 1 Bacterial transcriptional activator domain PknG_TPR PF16918.5 ORY41579.1 - 0.023 13.5 0.0 1 8.1 0.0 2.6 2 0 0 2 2 2 0 Protein kinase G tetratricopeptide repeat TPR_22 PF18833.1 ORY41579.1 - 0.027 14.6 0.1 0.079 13.1 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY41579.1 - 0.031 14.3 0.1 1.5 9.0 0.0 3.9 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat RPN7 PF10602.9 ORY41579.1 - 0.054 13.2 0.1 10 5.8 0.0 3.9 4 0 0 4 4 3 0 26S proteasome subunit RPN7 DUF4919 PF16266.5 ORY41579.1 - 0.13 12.2 0.8 25 4.8 0.0 4.3 4 2 1 5 5 5 0 Domain of unknown function (DUF4919) TPR_10 PF13374.6 ORY41579.1 - 0.41 10.6 20.7 12 6.0 0.1 9.1 11 0 0 11 11 9 0 Tetratricopeptide repeat Rota_NSP4 PF01452.16 ORY41579.1 - 0.97 9.1 2.8 11 5.7 1.3 2.5 2 0 0 2 2 2 0 Rotavirus non structural protein Guanylate_cyc PF00211.20 ORY41580.1 - 4.8e-50 169.7 0.0 1.3e-49 168.3 0.0 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PAS_9 PF13426.7 ORY41580.1 - 2e-09 37.6 0.7 1.6e-08 34.7 0.0 2.9 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 ORY41580.1 - 5.2e-05 23.2 0.0 5.2e-05 23.2 0.0 3.1 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 ORY41580.1 - 0.038 14.0 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 PAS domain APH PF01636.23 ORY41581.1 - 1.3e-12 48.2 0.0 3.6e-12 46.7 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 ORY41581.1 - 6.7e-12 45.0 0.0 1.2e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) EcKinase PF02958.20 ORY41581.1 - 1.3e-11 44.4 0.0 4.5e-10 39.3 0.0 2.3 2 1 0 2 2 2 1 Ecdysteroid kinase Choline_kinase PF01633.20 ORY41581.1 - 3.4e-05 23.5 0.1 6.6e-05 22.6 0.1 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase Peptidase_S58 PF03576.14 ORY41581.1 - 0.087 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S58 SNF2_N PF00176.23 ORY41584.1 - 6.8e-28 97.4 0.0 9.1e-27 93.7 0.0 2.1 1 1 1 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 ORY41584.1 - 2e-10 40.4 6.3 4.1e-10 39.4 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY41584.1 - 1.1e-08 35.2 9.0 1.1e-08 35.2 9.0 2.1 2 0 0 2 2 1 1 Ring finger domain ResIII PF04851.15 ORY41584.1 - 2.3e-06 27.7 0.5 1.2e-05 25.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.6 ORY41584.1 - 1.1e-05 25.2 7.6 2.4e-05 24.2 7.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY41584.1 - 1.7e-05 24.6 9.2 1.7e-05 24.6 9.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY41584.1 - 1.8e-05 24.4 8.5 1.8e-05 24.4 8.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY41584.1 - 2.9e-05 24.0 4.7 8.5e-05 22.5 4.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 ORY41584.1 - 5.1e-05 23.0 6.7 0.00011 22.0 6.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 ORY41584.1 - 0.00037 20.2 6.9 0.0008 19.2 6.9 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 ORY41584.1 - 0.0033 17.1 4.5 0.012 15.4 4.5 2.0 1 0 0 1 1 1 1 RING-like zinc finger DUF1272 PF06906.11 ORY41584.1 - 0.0093 16.0 4.6 0.021 14.9 4.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) DUF4201 PF13870.6 ORY41584.1 - 0.012 15.4 4.4 0.029 14.1 4.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Helicase_C PF00271.31 ORY41584.1 - 0.022 15.1 0.1 0.15 12.4 0.0 2.4 2 1 0 2 2 2 0 Helicase conserved C-terminal domain PEARLI-4 PF05278.12 ORY41584.1 - 0.1 12.2 4.1 0.22 11.1 4.1 1.5 1 0 0 1 1 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) zf-rbx1 PF12678.7 ORY41584.1 - 0.1 12.9 6.7 0.25 11.6 6.7 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Terminase_2 PF03592.16 ORY41584.1 - 0.11 13.0 5.5 0.25 11.8 3.5 2.3 2 0 0 2 2 2 0 Terminase small subunit DUF4061 PF13270.6 ORY41584.1 - 0.12 12.8 1.7 0.26 11.6 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) AAA_13 PF13166.6 ORY41584.1 - 0.14 10.8 4.7 0.21 10.2 4.7 1.2 1 0 0 1 1 1 0 AAA domain DUF4200 PF13863.6 ORY41584.1 - 0.25 11.7 8.5 0.64 10.4 8.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Atg14 PF10186.9 ORY41584.1 - 0.34 9.9 3.0 0.66 9.0 3.0 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 zinc-ribbons_6 PF07191.12 ORY41584.1 - 0.69 9.9 5.9 1.5 8.9 5.9 1.6 1 0 0 1 1 1 0 zinc-ribbons DUF4407 PF14362.6 ORY41584.1 - 0.84 8.9 4.6 1.5 8.1 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 ORY41584.1 - 1.3 9.2 9.2 4.1 7.7 9.2 1.8 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Rtf2 PF04641.12 ORY41584.1 - 1.7 7.9 10.1 0.14 11.5 1.6 2.2 2 0 0 2 2 2 0 Rtf2 RING-finger zf-C3HC4_4 PF15227.6 ORY41584.1 - 2.2 8.5 8.2 5.7 7.2 8.2 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DZR PF12773.7 ORY41584.1 - 2.3 8.3 4.9 5.2 7.2 4.9 1.5 1 0 0 1 1 1 0 Double zinc ribbon IBR PF01485.21 ORY41584.1 - 8.9 6.6 8.7 24 5.2 6.6 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain MFS_1 PF07690.16 ORY41585.1 - 1.6e-09 37.1 20.5 1.6e-09 37.1 20.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily LRR_8 PF13855.6 ORY41586.1 - 2e-11 43.5 37.5 1.5e-05 24.7 8.9 3.5 1 1 4 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 ORY41586.1 - 6.8e-07 29.5 26.1 0.0044 17.4 9.0 4.2 1 1 2 4 4 4 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORY41586.1 - 0.00077 19.3 0.5 0.0019 18.1 0.5 1.7 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 ORY41586.1 - 0.0093 15.9 16.7 7.4 6.9 0.7 5.8 5 0 0 5 5 5 3 Leucine Rich repeat F-box PF00646.33 ORY41586.1 - 0.013 15.4 1.6 0.056 13.3 0.9 2.4 2 0 0 2 2 2 0 F-box domain LRR_1 PF00560.33 ORY41586.1 - 1.5 9.7 25.8 40 5.3 0.3 6.2 4 2 1 5 5 5 0 Leucine Rich Repeat Utp21 PF04192.12 ORY41587.1 - 7.2e-33 114.0 3.2 2e-31 109.3 3.2 2.2 1 1 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 ORY41587.1 - 1.5e-25 88.9 18.9 2.7e-05 24.8 0.1 10.6 11 0 0 11 11 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY41587.1 - 3.4e-17 62.5 0.0 0.0016 18.7 0.0 7.1 4 2 5 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY41587.1 - 0.00091 18.0 1.5 1.8 7.1 0.3 3.4 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Utp12 PF04003.12 ORY41587.1 - 0.0012 19.1 0.2 0.0027 18.0 0.2 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.11 ORY41587.1 - 0.0016 18.4 0.0 0.0093 15.9 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 ORY41587.1 - 0.0022 17.1 0.2 0.77 8.7 0.1 2.7 3 0 0 3 3 3 2 Coatomer WD associated region Nucleoporin_N PF08801.11 ORY41587.1 - 0.0026 16.6 0.5 0.13 10.9 0.0 2.9 2 1 1 3 3 3 1 Nup133 N terminal like Nbas_N PF15492.6 ORY41587.1 - 0.02 14.2 0.0 0.061 12.7 0.0 1.9 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal PGM_PMM_I PF02878.16 ORY41588.1 - 3.5e-16 59.2 0.1 2.8e-07 30.3 0.0 2.9 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 ORY41588.1 - 2e-10 40.7 0.1 8.2e-10 38.7 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 ORY41588.1 - 0.039 14.2 0.1 0.1 12.8 0.1 1.9 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III tRNA-synt_His PF13393.6 ORY41588.1 - 0.1 11.8 0.1 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Histidyl-tRNA synthetase PGM_PMM_II PF02879.16 ORY41588.1 - 0.16 12.6 0.2 1.4 9.6 0.2 2.6 1 1 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Aldedh PF00171.22 ORY41589.1 - 4.7e-120 401.2 0.1 5.8e-120 400.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family zf-C2H2_4 PF13894.6 ORY41590.1 - 1.7e-07 31.5 16.1 0.006 17.3 2.5 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY41590.1 - 3.6e-07 30.3 19.2 0.0003 21.1 2.3 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY41590.1 - 5.1e-05 23.5 16.9 0.00013 22.2 1.2 4.6 5 0 0 5 5 5 2 Zinc-finger double domain zf-Di19 PF05605.12 ORY41590.1 - 0.00019 21.6 3.1 0.00019 21.6 3.1 2.0 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 ORY41590.1 - 0.0077 16.2 1.0 0.0077 16.2 1.0 2.0 2 0 0 2 2 2 1 BED zinc finger zf-C2H2_jaz PF12171.8 ORY41590.1 - 0.065 13.5 12.5 0.77 10.1 0.6 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zinc-ribbons_6 PF07191.12 ORY41590.1 - 0.2 11.7 4.3 2.8 8.0 1.0 2.4 2 0 0 2 2 2 0 zinc-ribbons FOXP-CC PF16159.5 ORY41590.1 - 1.8 9.3 5.0 0.42 11.3 1.2 2.0 2 1 0 2 2 2 0 FOXP coiled-coil domain zf-met PF12874.7 ORY41590.1 - 3.2 8.3 10.4 6.5 7.3 0.1 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 ORY41590.1 - 5 7.5 6.7 35 4.8 0.0 2.9 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) LIM PF00412.22 ORY41590.1 - 6.4 7.1 8.2 15 5.9 2.3 2.8 2 1 0 2 2 2 0 LIM domain HNH_5 PF14279.6 ORY41590.1 - 9.2 6.2 6.5 24 4.9 0.6 2.6 2 1 0 2 2 2 0 HNH endonuclease FGGY_C PF02782.16 ORY41592.1 - 3.6e-63 212.9 0.0 6.5e-63 212.0 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 ORY41592.1 - 1.8e-61 207.9 0.1 2.7e-61 207.3 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FAD_binding_4 PF01565.23 ORY41592.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 FAD binding domain DHC_N1 PF08385.12 ORY41594.1 - 2.9e-179 597.4 14.4 2.9e-179 597.4 14.4 3.4 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 ORY41594.1 - 7.8e-119 397.3 3.3 7.8e-119 397.3 3.3 4.8 3 1 1 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 ORY41594.1 - 6.7e-106 354.0 0.1 7.8e-54 182.8 0.0 3.2 1 1 1 2 2 2 2 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 ORY41594.1 - 1.5e-96 323.3 0.0 1.5e-96 323.3 0.0 3.6 4 0 0 4 4 4 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 ORY41594.1 - 5.9e-55 185.6 0.3 2.7e-51 173.7 0.1 4.0 3 1 0 3 3 3 1 P-loop containing dynein motor region AAA_9 PF12781.7 ORY41594.1 - 1.3e-48 165.1 3.1 1.3e-48 165.1 3.1 2.9 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 ORY41594.1 - 2.9e-48 164.4 3.5 5.1e-27 94.8 0.2 3.7 1 1 1 2 2 2 2 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 ORY41594.1 - 2.9e-42 144.3 0.0 7.7e-42 142.9 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 ORY41594.1 - 2.8e-36 124.2 0.2 2e-35 121.5 0.0 2.8 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 ORY41594.1 - 4.6e-19 68.5 0.1 5e-18 65.1 0.0 2.9 2 0 0 2 2 2 1 AAA+ lid domain MT PF12777.7 ORY41594.1 - 1.5e-16 60.3 1.4 1.5e-16 60.3 1.4 2.9 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 ORY41594.1 - 3.4e-10 40.0 0.1 5.6e-05 23.2 0.0 5.1 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 ORY41594.1 - 4.3e-06 26.8 0.0 2.4e-05 24.4 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 ORY41594.1 - 6.7e-05 23.3 0.0 0.39 11.1 0.0 4.1 3 0 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 ORY41594.1 - 0.00013 22.4 0.3 0.076 13.4 0.0 3.3 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY41594.1 - 0.0032 17.7 5.2 0.18 12.1 0.0 3.9 4 0 0 4 4 3 1 AAA domain Bac_DNA_binding PF00216.21 ORY41594.1 - 0.072 13.3 1.0 0.45 10.7 0.3 2.7 2 0 0 2 2 2 0 Bacterial DNA-binding protein AAA_19 PF13245.6 ORY41594.1 - 0.18 12.1 5.2 3.4 8.0 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.6 ORY41594.1 - 0.26 11.1 3.2 2.3 7.9 0.0 3.7 4 0 0 4 4 4 0 AAA domain AAA_30 PF13604.6 ORY41594.1 - 1.2 8.8 7.5 32 4.2 0.0 4.1 4 0 0 4 4 4 0 AAA domain Trs65 PF12735.7 ORY41595.1 - 1.1e-16 61.1 1.5 7.5e-15 55.1 1.5 2.4 1 1 0 1 1 1 1 TRAPP trafficking subunit Trs65 DUF1724 PF08350.10 ORY41595.1 - 0.071 13.3 0.0 0.25 11.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1724) SufE PF02657.15 ORY41596.1 - 0.011 15.6 0.6 0.32 10.9 0.0 2.7 2 1 0 2 2 2 0 Fe-S metabolism associated domain DUF4600 PF15372.6 ORY41596.1 - 0.017 15.6 1.2 0.017 15.6 1.2 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4600) HALZ PF02183.18 ORY41596.1 - 0.023 14.9 0.3 0.023 14.9 0.3 4.0 5 1 0 5 5 5 0 Homeobox associated leucine zipper DivIC PF04977.15 ORY41596.1 - 0.041 13.7 0.4 0.041 13.7 0.4 4.4 4 1 0 5 5 5 0 Septum formation initiator Baculo_PEP_C PF04513.12 ORY41596.1 - 0.13 12.3 20.3 0.4 10.7 0.3 3.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4786 PF16027.5 ORY41596.1 - 0.15 12.7 1.8 0.39 11.3 1.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4786) ZapB PF06005.12 ORY41596.1 - 0.16 12.4 23.5 1.1 9.7 7.6 4.0 3 1 0 3 3 3 0 Cell division protein ZapB T3SSipB PF16535.5 ORY41596.1 - 4.4 7.8 16.6 5 7.6 4.5 2.4 2 0 0 2 2 2 0 Type III cell invasion protein SipB Hrs_helical PF12210.8 ORY41596.1 - 6 7.5 17.7 0.43 11.2 3.2 3.8 2 2 2 4 4 4 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Cullin PF00888.22 ORY41597.1 - 1e-22 80.5 2.7 1.4e-22 80.1 2.7 1.2 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 ORY41597.1 - 5.3e-12 46.1 0.0 1.7e-11 44.4 0.0 2.0 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 F_bP_aldolase PF01116.20 ORY41597.1 - 0.074 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II Phage_rep_O PF04492.13 ORY41597.1 - 0.11 13.1 0.0 0.54 10.9 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage replication protein O Formyl_trans_N PF00551.19 ORY41598.1 - 7.3e-29 100.8 0.0 1e-28 100.3 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 ORY41598.1 - 3.1e-13 49.8 0.0 6.2e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain CDtoxinA PF03498.14 ORY41599.1 - 0.24 11.0 4.4 9.2 5.8 0.0 2.8 2 1 1 3 3 3 0 Cytolethal distending toxin A/C domain ECH_1 PF00378.20 ORY41600.1 - 1e-38 133.1 0.1 1.4e-38 132.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY41600.1 - 7.5e-16 58.5 0.1 1.2e-15 57.9 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Lipase_3 PF01764.25 ORY41601.1 - 1.3e-29 102.9 0.0 1.8e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORY41601.1 - 0.014 16.0 0.0 0.017 15.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.14 ORY41601.1 - 0.047 13.2 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Cutinase PF01083.22 ORY41601.1 - 0.08 12.9 0.0 0.19 11.6 0.0 1.6 2 0 0 2 2 2 0 Cutinase adh_short PF00106.25 ORY41602.1 - 2.5e-05 23.8 0.3 2.8e-05 23.7 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY41602.1 - 0.006 16.5 0.2 0.0064 16.4 0.2 1.0 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY41602.1 - 0.027 13.6 0.1 0.031 13.4 0.1 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 ORY41602.1 - 0.031 14.5 0.2 0.036 14.3 0.2 1.0 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short_C2 PF13561.6 ORY41602.1 - 0.036 13.6 0.2 0.042 13.4 0.2 1.0 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase adh_short_C2 PF13561.6 ORY41603.1 - 2.2e-32 112.5 0.1 2.6e-32 112.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY41603.1 - 3.7e-13 49.4 0.0 5.3e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase TPR_19 PF14559.6 ORY41604.1 - 0.0022 18.4 0.1 0.0031 18.0 0.1 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY41604.1 - 0.04 14.8 0.0 0.073 13.9 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY41604.1 - 0.045 14.0 0.1 0.059 13.6 0.1 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Ras PF00071.22 ORY41605.1 - 1.1e-07 31.6 0.0 4.2e-06 26.4 0.0 2.1 1 1 1 2 2 2 2 Ras family Roc PF08477.13 ORY41605.1 - 0.018 15.2 0.0 0.1 12.8 0.0 1.9 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF3591 PF12157.8 ORY41606.1 - 8.7e-144 479.5 0.1 1.2e-143 479.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 ORY41606.1 - 3.2e-17 62.4 0.0 9.6e-17 60.8 0.0 1.8 1 0 0 1 1 1 1 Bromodomain Mog1 PF04603.12 ORY41607.1 - 5.4e-34 117.5 0.1 6.6e-34 117.2 0.1 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein DCAF15_WD40 PF14939.6 ORY41607.1 - 0.043 13.5 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat Kinesin PF00225.23 ORY41608.1 - 1.4e-47 162.3 0.3 5.3e-47 160.4 0.3 1.9 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY41608.1 - 1.1e-09 38.5 0.1 4.8e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding ResIII PF04851.15 ORY41608.1 - 0.0034 17.4 0.0 0.0094 16.0 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF87 PF01935.17 ORY41608.1 - 0.0054 16.9 0.0 0.013 15.6 0.0 1.8 1 1 0 1 1 1 1 Helicase HerA, central domain AAA_22 PF13401.6 ORY41608.1 - 0.079 13.2 0.1 0.71 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORY41608.1 - 0.13 12.6 0.0 0.33 11.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase RunxI PF08504.11 ORY41608.1 - 0.73 10.6 3.8 11 6.8 0.1 2.7 2 0 0 2 2 2 0 Runx inhibition domain LRR_8 PF13855.6 ORY41609.1 - 3.3e-27 94.0 31.3 2.2e-11 43.3 7.5 5.4 3 1 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 ORY41609.1 - 1.7e-18 66.4 28.2 1.2e-06 28.8 0.6 6.8 3 2 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY41609.1 - 1.3e-17 61.6 30.9 0.015 15.7 0.3 10.2 11 0 0 11 11 11 7 Leucine Rich Repeat LRR_6 PF13516.6 ORY41609.1 - 4.7e-08 32.5 30.0 0.045 13.8 0.9 8.7 10 0 0 10 10 10 4 Leucine Rich repeat KLRAQ PF10205.9 ORY41612.1 - 1.1e-17 64.0 1.2 1.1e-17 64.0 1.2 2.3 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein SHE3 PF17078.5 ORY41612.1 - 0.002 17.9 10.9 0.017 14.9 3.0 2.1 2 0 0 2 2 2 2 SWI5-dependent HO expression protein 3 ATG16 PF08614.11 ORY41612.1 - 0.004 17.4 1.3 0.004 17.4 1.3 2.2 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 ORY41612.1 - 0.023 14.8 13.6 0.87 9.7 6.3 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF3450 PF11932.8 ORY41612.1 - 0.027 13.8 1.2 0.027 13.8 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) KELK PF15796.5 ORY41612.1 - 0.042 14.3 1.7 0.042 14.3 1.7 2.8 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GAS PF13851.6 ORY41612.1 - 0.078 12.3 18.7 0.75 9.1 1.6 2.8 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 ORY41612.1 - 0.078 13.2 18.0 3.2 8.0 2.1 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 ORY41612.1 - 0.08 13.0 16.5 0.56 10.3 7.9 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein K_channel_TID PF07941.11 ORY41612.1 - 0.12 12.9 3.9 0.21 12.0 3.9 1.4 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain HrpB7 PF09486.10 ORY41612.1 - 0.19 12.1 9.4 0.22 11.9 0.8 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF1474 PF07342.11 ORY41612.1 - 0.33 11.5 2.0 0.52 10.9 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1474) Sigma54_AID PF00309.20 ORY41612.1 - 0.55 10.1 8.4 0.25 11.2 0.8 2.8 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) HALZ PF02183.18 ORY41612.1 - 0.76 10.0 13.5 6.8 7.0 0.3 3.9 4 0 0 4 4 3 0 Homeobox associated leucine zipper CorA PF01544.18 ORY41612.1 - 2.4 7.4 11.4 1.2 8.4 1.8 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein FPP PF05911.11 ORY41612.1 - 2.5 6.2 22.3 1.8 6.7 14.7 2.4 1 1 2 3 3 3 0 Filament-like plant protein, long coiled-coil DHR10 PF18595.1 ORY41612.1 - 2.7 8.1 22.0 5.8 7.0 2.4 3.5 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain APG6_N PF17675.1 ORY41612.1 - 3.7 8.1 19.1 0.98 9.9 6.7 2.4 3 0 0 3 3 2 0 Apg6 coiled-coil region TMPIT PF07851.13 ORY41612.1 - 4.6 6.4 9.2 2.4 7.3 3.6 2.1 2 0 0 2 2 2 0 TMPIT-like protein TSNAXIP1_N PF15739.5 ORY41612.1 - 4.7 7.6 10.2 12 6.3 3.4 2.6 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus Fez1 PF06818.15 ORY41612.1 - 5 7.5 16.9 2.3e+02 2.1 16.9 2.1 1 1 0 1 1 1 0 Fez1 DUF641 PF04859.12 ORY41612.1 - 7.6 6.9 11.3 2.2 8.6 0.2 3.1 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) YabA PF06156.13 ORY41612.1 - 8 7.2 15.2 12 6.6 2.7 3.8 1 1 3 4 4 4 0 Initiation control protein YabA UPF0449 PF15136.6 ORY41612.1 - 8.1 7.0 8.5 4.5 7.8 2.1 2.8 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 Glyco_transf_34 PF05637.12 ORY41613.1 - 3.3e-15 56.5 2.8 2.5e-13 50.3 2.8 2.3 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family HLH PF00010.26 ORY41614.1 - 9.9e-07 28.6 0.2 1.9e-06 27.8 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain TFIIA PF03153.13 ORY41614.1 - 0.1 12.6 15.5 0.14 12.2 15.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5094 PF17015.5 ORY41614.1 - 0.38 10.8 2.2 2.4 8.2 2.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5094) SR-25 PF10500.9 ORY41614.1 - 1.1 8.8 15.4 0.12 12.0 6.0 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Striatin PF08232.12 ORY41614.1 - 4 8.0 8.2 0.32 11.6 1.5 2.3 3 0 0 3 3 3 0 Striatin family CCDC106 PF15794.5 ORY41614.1 - 4.4 7.0 9.7 1.2 8.8 5.3 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 zf-MYND PF01753.18 ORY41615.1 - 8.8e-09 35.3 9.1 8.8e-09 35.3 9.1 1.7 2 0 0 2 2 2 1 MYND finger TPR_2 PF07719.17 ORY41615.1 - 0.0014 18.6 4.0 0.023 14.8 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY41615.1 - 0.0058 16.8 2.4 0.24 11.7 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY41615.1 - 0.019 15.6 0.7 0.48 11.1 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY41615.1 - 0.18 11.7 2.1 0.71 9.8 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY41615.1 - 0.38 11.1 2.2 13 6.1 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_8 PF13855.6 ORY41617.1 - 2.9e-21 75.0 23.3 1.5e-08 34.3 1.6 2.7 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY41617.1 - 2.5e-11 43.6 6.2 0.00034 20.9 1.0 3.2 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY41617.1 - 3.8e-08 32.8 6.6 1.2 9.9 0.1 4.6 5 0 0 5 5 5 4 Leucine Rich Repeat LRR_6 PF13516.6 ORY41617.1 - 0.015 15.3 7.8 2.3 8.5 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich repeat SKICH PF17751.1 ORY41617.1 - 0.054 14.0 0.0 0.08 13.5 0.0 1.3 1 0 0 1 1 1 0 SKICH domain LRR_6 PF13516.6 ORY41618.1 - 1.2e-15 56.1 0.6 0.011 15.7 0.0 7.5 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.7 ORY41618.1 - 2.1e-05 24.8 14.0 6.9 7.2 0.0 7.3 2 1 7 9 9 9 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY41618.1 - 0.00045 19.9 4.6 8 6.3 0.0 6.1 7 1 0 7 7 7 1 Leucine rich repeat Roughex PF06020.11 ORY41618.1 - 0.0043 16.2 1.7 0.0089 15.2 1.8 1.5 2 0 0 2 2 2 1 Drosophila roughex protein LRR_1 PF00560.33 ORY41618.1 - 0.013 15.9 4.8 8.2 7.4 0.1 5.7 4 2 0 4 4 4 0 Leucine Rich Repeat LRR_9 PF14580.6 ORY41618.1 - 0.095 12.2 1.8 13 5.2 0.7 3.2 2 1 1 3 3 3 0 Leucine-rich repeat Importin_rep_4 PF18808.1 ORY41618.1 - 0.33 11.3 4.0 0.66 10.3 4.0 1.5 1 0 0 1 1 1 0 Importin repeat DNA_pol_phi PF04931.13 ORY41618.1 - 8.2 4.4 6.5 14 3.6 6.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi WBS28 PF15164.6 ORY41624.1 - 0.01 15.2 2.9 0.016 14.5 2.9 1.3 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue Tmemb_9 PF05434.11 ORY41624.1 - 0.038 13.9 0.4 0.068 13.1 0.2 1.4 1 1 0 1 1 1 0 TMEM9 ABC_membrane_2 PF06472.15 ORY41625.1 - 2.3e-37 128.9 8.7 1.4e-28 100.0 0.5 2.4 3 0 0 3 3 2 2 ABC transporter transmembrane region 2 ABC_tran PF00005.27 ORY41625.1 - 8.3e-17 62.0 0.0 1.5e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 ORY41625.1 - 5.7e-06 26.8 0.0 1.4e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ORY41625.1 - 2.8e-05 23.8 0.0 6.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 ORY41625.1 - 3.9e-05 23.9 0.0 0.00012 22.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain NACHT PF05729.12 ORY41625.1 - 0.0012 18.8 0.0 0.052 13.5 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.6 ORY41625.1 - 0.0038 17.1 0.0 0.0069 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ORY41625.1 - 0.0041 17.6 0.0 0.0096 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.18 ORY41625.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 ORY41625.1 - 0.016 15.1 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 ORY41625.1 - 0.018 14.6 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 ORY41625.1 - 0.019 14.9 0.0 0.05 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SMC_N PF02463.19 ORY41625.1 - 0.021 14.3 0.0 0.26 10.7 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 ORY41625.1 - 0.048 13.4 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORY41625.1 - 0.052 14.1 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF3987 PF13148.6 ORY41625.1 - 0.099 11.6 0.0 4.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Adeno_IVa2 PF02456.15 ORY41625.1 - 0.099 11.4 0.2 0.32 9.7 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein Rad17 PF03215.15 ORY41625.1 - 0.13 12.2 0.1 1 9.3 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain cobW PF02492.19 ORY41625.1 - 0.13 11.8 0.1 0.34 10.5 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Cytidylate_kin PF02224.18 ORY41625.1 - 0.14 11.8 0.0 0.4 10.4 0.0 1.6 1 0 0 1 1 1 0 Cytidylate kinase Mg_chelatase PF01078.21 ORY41625.1 - 0.16 11.3 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Glyco_hydro_35 PF01301.19 ORY41626.1 - 1.8e-100 336.6 1.8 2.4e-100 336.2 1.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 ORY41626.1 - 1.1e-08 34.8 5.3 3.7e-08 33.1 2.1 2.5 1 1 1 2 2 2 1 Beta-galactosidase GHD PF17834.1 ORY41626.1 - 1.8e-05 24.7 0.0 5.3e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Beta-sandwich domain in beta galactosidase Abhydrolase_3 PF07859.13 ORY41627.1 - 8.2e-36 123.9 0.0 6.4e-35 120.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY41627.1 - 9.4e-07 28.0 0.0 1.3e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 ORY41627.1 - 0.042 13.1 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 COX7C PF02935.16 ORY41628.1 - 0.032 14.5 0.4 0.032 14.5 0.4 1.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc CobS PF02654.15 ORY41629.1 - 8.7e-32 111.0 12.1 1.3e-31 110.4 12.1 1.3 1 0 0 1 1 1 1 Cobalamin-5-phosphate synthase Hepar_II_III PF07940.13 ORY41630.1 - 6.6e-18 65.2 0.3 1.1e-17 64.5 0.3 1.2 1 0 0 1 1 1 1 Heparinase II/III-like protein DUF4962 PF16332.5 ORY41630.1 - 1.8e-16 59.7 1.2 6.2e-16 58.0 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4962) NOG1_N PF17835.1 ORY41633.1 - 2.9e-54 183.4 1.0 8e-54 181.9 1.0 1.8 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOG1 PF06858.14 ORY41633.1 - 1.1e-26 92.3 0.1 2.2e-26 91.4 0.1 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 ORY41633.1 - 7.4e-26 89.9 2.4 1.6e-25 88.9 2.4 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 ORY41633.1 - 1.2e-19 70.5 0.0 2.7e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY41633.1 - 5.9e-11 42.1 0.0 1.1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 ORY41633.1 - 0.0025 17.4 0.0 0.0054 16.3 0.0 1.6 1 0 0 1 1 1 1 Ras family Dynamin_N PF00350.23 ORY41633.1 - 0.0026 17.8 1.5 0.39 10.8 0.0 3.1 2 1 1 3 3 3 1 Dynamin family AAA_18 PF13238.6 ORY41633.1 - 0.0033 18.0 0.6 1.1 9.9 0.0 4.0 4 1 0 4 4 4 1 AAA domain AIG1 PF04548.16 ORY41633.1 - 0.0041 16.5 0.0 0.021 14.1 0.0 2.1 2 0 0 2 2 2 1 AIG1 family SRPRB PF09439.10 ORY41633.1 - 0.0087 15.5 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 ORY41633.1 - 0.016 15.1 0.1 0.57 10.1 0.0 2.8 2 1 0 2 2 2 0 RsgA GTPase Roc PF08477.13 ORY41633.1 - 0.02 15.1 0.0 0.13 12.5 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 ORY41633.1 - 0.083 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_16 PF13191.6 ORY41633.1 - 0.11 12.8 4.5 0.15 12.4 0.0 3.1 2 2 0 2 2 1 0 AAA ATPase domain Lip_prot_lig_C PF10437.9 ORY41633.1 - 0.15 12.0 0.7 0.69 9.9 0.0 2.4 3 0 0 3 3 3 0 Bacterial lipoate protein ligase C-terminus TRIF-NTD PF17798.1 ORY41634.1 - 0.1 12.7 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 TRIF N-terminal domain Glyco_hydro_18 PF00704.28 ORY41636.1 - 4.2e-18 66.1 0.1 4.2e-18 66.1 0.1 1.8 2 1 0 2 2 2 1 Glycosyl hydrolases family 18 WD40 PF00400.32 ORY41637.1 - 8.7e-07 29.6 8.1 0.026 15.4 0.1 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY41637.1 - 0.0001 22.5 0.0 3.1 8.1 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Secretin_N PF03958.17 ORY41637.1 - 0.081 13.3 0.1 0.2 12.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain Phage_T4_gp36 PF03903.13 ORY41637.1 - 0.1 12.6 0.3 0.15 12.0 0.3 1.2 1 0 0 1 1 1 0 Phage T4 tail fibre Pro_Al_protease PF02983.14 ORY41637.1 - 0.57 10.3 2.9 0.51 10.4 0.2 2.2 2 0 0 2 2 2 0 Alpha-lytic protease prodomain DUF2218 PF09981.9 ORY41638.1 - 0.15 12.5 0.3 0.66 10.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2218) RRM_1 PF00076.22 ORY41639.1 - 1e-37 127.8 0.0 1.8e-13 50.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY41639.1 - 8e-05 22.6 0.0 0.25 11.4 0.0 3.1 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 ORY41639.1 - 0.0023 17.8 0.0 1.9 8.5 0.0 2.7 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif AstE_AspA PF04952.14 ORY41640.1 - 2.2e-33 115.6 0.0 4.1e-33 114.7 0.0 1.4 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family HutD PF05962.11 ORY41640.1 - 3.1e-22 79.4 0.0 1.9e-15 57.3 0.0 3.2 3 0 0 3 3 3 3 HutD GMC_oxred_N PF00732.19 ORY41641.1 - 1.3e-37 129.8 4.6 4.2e-34 118.3 0.5 2.4 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY41641.1 - 6.9e-25 88.2 0.2 1.3e-24 87.4 0.2 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ORY41641.1 - 0.00083 18.5 0.0 0.0013 18.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY41641.1 - 0.02 14.5 0.0 0.045 13.3 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF4318 PF14201.6 ORY41641.1 - 0.073 13.6 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4318) Ank_2 PF12796.7 ORY41642.1 - 0.013 16.1 0.1 2.1 9.0 0.0 3.4 3 1 0 3 3 3 0 Ankyrin repeats (3 copies) PCIF1_WW PF12237.8 ORY41643.1 - 7.8e-53 178.6 0.1 1.3e-52 177.8 0.1 1.3 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain Citrate_synt PF00285.21 ORY41644.1 - 3e-137 457.5 0.0 3.5e-137 457.3 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Galactosyl_T PF01762.21 ORY41645.1 - 2e-12 47.4 0.1 2.6e-08 33.9 0.3 2.9 1 1 1 2 2 2 2 Galactosyltransferase Fringe PF02434.16 ORY41645.1 - 0.00097 18.6 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 Fringe-like bPH_1 PF08000.11 ORY41646.1 - 1.3e-13 51.1 0.0 1.8e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial PH domain PCNA_N PF00705.18 ORY41647.1 - 1.7e-50 170.0 3.4 1.8e-50 169.9 1.8 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 ORY41647.1 - 7.6e-48 161.9 0.5 2.6e-46 157.0 0.1 2.1 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 ORY41647.1 - 3.2e-08 33.4 0.1 3.7e-08 33.1 0.1 1.0 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 ORY41647.1 - 2.2e-07 30.2 2.9 1.9e-05 23.9 2.9 2.1 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.12 ORY41647.1 - 0.03 13.4 0.3 0.2 10.8 0.1 2.0 2 1 0 2 2 2 0 Hus1-like protein DNA_pol3_beta_3 PF02768.15 ORY41647.1 - 0.037 13.9 0.0 0.097 12.5 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III beta subunit, C-terminal domain zf-C2H2 PF00096.26 ORY41648.1 - 6.9e-10 38.8 5.7 7.6e-06 26.1 1.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 ORY41648.1 - 4.8e-05 23.5 2.3 5.9e-05 23.2 0.4 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 ORY41648.1 - 0.00016 22.2 1.0 0.00016 22.2 1.0 2.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.7 ORY41648.1 - 0.0014 19.0 0.9 0.004 17.5 0.2 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 ORY41648.1 - 0.0037 17.6 0.3 0.0037 17.6 0.3 3.5 4 0 0 4 4 4 2 Zinc-finger double domain Zn_ribbon_SprT PF17283.2 ORY41648.1 - 0.021 14.7 0.6 0.021 14.7 0.6 2.0 1 1 1 2 2 2 0 SprT-like zinc ribbon domain DUF4097 PF13349.6 ORY41650.1 - 1.1e-12 47.9 27.1 9.2e-10 38.3 14.2 3.1 1 1 1 2 2 2 2 Putative adhesin SH3_15 PF18346.1 ORY41650.1 - 0.016 15.5 2.7 0.017 15.5 1.1 1.9 2 0 0 2 2 2 0 Mind bomb SH3 repeat domain bZIP_1 PF00170.21 ORY41651.1 - 7e-07 29.2 13.5 5.8e-05 23.1 7.8 2.9 3 0 0 3 3 3 2 bZIP transcription factor bZIP_2 PF07716.15 ORY41651.1 - 5.2e-05 23.2 16.3 0.00051 20.1 10.3 2.3 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.17 ORY41651.1 - 0.017 15.7 7.3 0.39 11.3 5.4 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF4589 PF15252.6 ORY41651.1 - 0.39 10.7 6.6 0.25 11.3 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4589) DUF1484 PF07363.11 ORY41651.1 - 1.3 10.0 5.5 0.47 11.5 1.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1484) eIF3_N PF09440.10 ORY41652.1 - 0.077 13.4 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain CCDC106 PF15794.5 ORY41654.1 - 1.7 8.3 8.8 3 7.5 8.8 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 LRR_4 PF12799.7 ORY41655.1 - 0.011 16.1 1.0 0.029 14.8 1.0 1.7 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) bZIP_1 PF00170.21 ORY41657.1 - 0.0013 18.7 2.5 0.0037 17.3 1.0 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_1 PF00170.21 ORY41659.1 - 5.9e-05 23.1 8.6 0.00013 22.0 8.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor Mto2_bdg PF12808.7 ORY41659.1 - 0.019 15.2 0.7 0.041 14.2 0.7 1.5 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region PEX-1N PF09262.11 ORY41659.1 - 0.078 13.4 0.1 11 6.5 0.0 2.3 2 0 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal Phage_GP20 PF06810.11 ORY41659.1 - 0.1 12.4 0.6 0.14 11.9 0.6 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 bZIP_2 PF07716.15 ORY41659.1 - 4.4 7.5 15.5 0.68 10.1 6.7 2.7 1 1 1 3 3 3 0 Basic region leucine zipper bZIP_2 PF07716.15 ORY41660.1 - 0.00023 21.1 3.2 0.065 13.3 0.4 2.3 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 ORY41660.1 - 0.0036 17.4 4.7 0.091 12.9 0.9 2.3 1 1 1 2 2 2 2 bZIP transcription factor HAP1_N PF04849.13 ORY41660.1 - 0.029 13.6 0.5 0.044 13.0 0.5 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Drf_FH3 PF06367.16 ORY41660.1 - 0.13 11.8 0.2 0.29 10.7 0.2 1.5 1 0 0 1 1 1 0 Diaphanous FH3 Domain bZIP_1 PF00170.21 ORY41661.1 - 2.1e-07 31.0 6.8 0.0001 22.3 2.4 2.3 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 ORY41661.1 - 0.0012 18.8 7.6 0.0015 18.6 5.4 2.1 1 1 1 2 2 2 2 Basic region leucine zipper HAP1_N PF04849.13 ORY41661.1 - 0.0027 17.0 0.1 0.0037 16.5 0.1 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF2353 PF09789.9 ORY41661.1 - 0.053 12.9 0.2 0.073 12.4 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Tropomyosin PF00261.20 ORY41661.1 - 0.068 12.5 1.9 0.099 12.0 1.9 1.2 1 0 0 1 1 1 0 Tropomyosin TSC22 PF01166.18 ORY41661.1 - 0.07 13.4 0.2 0.3 11.4 0.1 2.0 1 1 1 2 2 2 0 TSC-22/dip/bun family Pex19 PF04614.12 ORY41661.1 - 0.086 12.6 0.8 0.12 12.2 0.8 1.1 1 0 0 1 1 1 0 Pex19 protein family PSI_PsaF PF02507.15 ORY41661.1 - 0.1 12.5 0.3 0.18 11.6 0.3 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III Glutaredoxin2_C PF04399.13 ORY41661.1 - 0.1 12.4 0.9 0.17 11.7 0.2 1.7 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain MapZ_EC1 PF18041.1 ORY41661.1 - 0.11 12.7 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 MapZ extracellular domain 1 BLOC1_2 PF10046.9 ORY41661.1 - 0.15 12.3 0.8 0.42 10.9 0.7 1.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Surfac_D-trimer PF09006.11 ORY41661.1 - 0.17 11.8 0.5 0.64 10.0 0.1 2.1 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation bZIP_1 PF00170.21 ORY41662.1 - 1.1e-06 28.6 9.1 0.00058 19.9 3.5 2.2 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 ORY41662.1 - 4.7e-06 26.6 6.9 0.0033 17.5 1.2 2.2 2 0 0 2 2 2 2 Basic region leucine zipper PRKG1_interact PF15898.5 ORY41662.1 - 0.047 14.6 1.9 0.063 14.2 1.9 1.2 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain TSC22 PF01166.18 ORY41662.1 - 0.068 13.5 0.1 0.16 12.3 0.0 1.7 2 0 0 2 2 2 0 TSC-22/dip/bun family Acyl-CoA_dh_2 PF08028.11 ORY41662.1 - 0.17 12.1 2.0 0.21 11.9 2.0 1.1 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain bZIP_1 PF00170.21 ORY41663.1 - 1.7e-07 31.2 9.4 4.4e-06 26.7 9.5 2.5 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY41663.1 - 0.0047 17.0 13.1 0.012 15.6 8.0 2.4 1 1 1 2 2 2 2 Basic region leucine zipper TSC22 PF01166.18 ORY41663.1 - 0.061 13.6 0.2 0.18 12.1 0.2 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family SOGA PF11365.8 ORY41663.1 - 0.28 12.4 2.6 0.68 11.1 2.6 1.7 1 1 0 1 1 1 0 Protein SOGA Mto2_bdg PF12808.7 ORY41663.1 - 6.3 7.2 10.5 15 6.0 3.3 3.1 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region bZIP_2 PF07716.15 ORY41664.1 - 0.0021 18.1 15.0 0.012 15.7 8.2 2.2 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 ORY41664.1 - 0.021 14.9 13.8 0.058 13.5 13.8 1.7 1 1 0 1 1 1 0 bZIP transcription factor Mto2_bdg PF12808.7 ORY41664.1 - 0.023 15.0 6.7 0.043 14.1 6.7 1.4 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region NAM-associated PF14303.6 ORY41664.1 - 0.29 11.8 5.2 0.39 11.4 5.2 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain bZIP_1 PF00170.21 ORY41665.1 - 3.8e-06 26.9 15.0 1.2e-05 25.3 15.0 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY41665.1 - 0.00046 20.2 16.3 0.0032 17.5 5.7 2.1 2 0 0 2 2 2 2 Basic region leucine zipper SR-25 PF10500.9 ORY41665.1 - 0.015 14.9 11.3 0.019 14.6 11.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SelA PF03841.13 ORY41665.1 - 0.035 13.1 0.4 0.042 12.8 0.4 1.0 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase NAM-associated PF14303.6 ORY41665.1 - 0.12 13.0 9.8 0.16 12.7 9.8 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain bZIP_1 PF00170.21 ORY41666.1 - 1.4e-05 25.1 8.1 2.6e-05 24.2 8.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY41666.1 - 0.0081 16.2 7.7 0.015 15.4 7.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ORY41667.1 - 0.00023 21.2 16.3 0.0004 20.4 16.3 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY41667.1 - 0.0082 16.2 18.7 0.0082 16.2 18.7 2.1 1 1 1 2 2 2 1 Basic region leucine zipper NAM-associated PF14303.6 ORY41667.1 - 0.55 10.9 9.3 0.78 10.4 9.3 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain bZIP_1 PF00170.21 ORY41668.1 - 2e-08 34.2 0.5 2e-08 34.2 0.5 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORY41668.1 - 0.0011 19.0 0.7 0.0021 18.1 0.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ORY41669.1 - 0.00037 20.5 12.9 0.0034 17.5 5.8 2.5 2 0 0 2 2 2 2 bZIP transcription factor PSI_PsaF PF02507.15 ORY41669.1 - 0.28 11.0 0.8 0.69 9.7 0.1 1.9 3 0 0 3 3 3 0 Photosystem I reaction centre subunit III RRM_3 PF08777.11 ORY41671.1 - 4.1e-13 49.3 0.6 1.5e-08 34.6 0.0 2.4 2 0 0 2 2 2 2 RNA binding motif RRM_1 PF00076.22 ORY41671.1 - 0.00021 21.0 0.0 0.015 15.1 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) La PF05383.17 ORY41671.1 - 0.0012 18.8 0.0 0.0031 17.5 0.0 1.7 1 0 0 1 1 1 1 La domain bZIP_1 PF00170.21 ORY41672.1 - 0.013 15.5 0.2 0.013 15.5 0.2 2.6 2 0 0 2 2 2 0 bZIP transcription factor zf-AD PF07776.15 ORY41672.1 - 0.04 14.2 0.1 0.12 12.7 0.1 1.8 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) DNA_pol3_gamma3 PF12169.8 ORY41672.1 - 0.049 13.5 0.7 0.76 9.7 0.1 2.5 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III Zn_clus PF00172.18 ORY41673.1 - 2.7e-18 65.8 20.9 1.9e-09 37.5 7.8 2.2 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 ORY41673.1 - 0.48 10.8 20.9 1.5 9.2 6.5 3.1 2 1 1 3 3 3 0 Opy2 protein PADR1 PF08063.12 ORY41673.1 - 8.4 6.3 16.0 0.34 10.7 4.0 2.6 2 1 0 2 2 2 0 PADR1 (NUC008) domain SnoaL_2 PF12680.7 ORY41674.1 - 1.6e-12 48.0 0.0 1.8e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ORY41674.1 - 0.00013 21.8 0.0 0.00054 19.8 0.0 2.0 2 1 0 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_3 PF13474.6 ORY41674.1 - 0.00081 19.6 0.0 0.0015 18.8 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 ORY41674.1 - 0.0059 17.0 0.0 0.0075 16.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) ATP-synt_ab PF00006.25 ORY41675.1 - 1.5e-72 243.7 0.0 2.6e-72 243.0 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 ORY41675.1 - 1.5e-47 161.1 0.1 2.6e-47 160.3 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 ORY41675.1 - 4e-20 72.1 3.2 7e-20 71.3 2.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 ORY41675.1 - 0.038 14.1 1.4 0.14 12.3 0.9 2.3 2 0 0 2 2 2 0 HAS barrel domain Radical_SAM_C PF16199.5 ORY41675.1 - 0.16 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Radical_SAM C-terminal domain Cwf_Cwc_15 PF04889.12 ORY41676.1 - 9.9e-65 218.7 28.7 2.3e-64 217.5 28.7 1.5 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.14 ORY41676.1 - 0.0042 15.4 17.7 0.0049 15.2 17.7 1.1 1 0 0 1 1 1 1 CDC45-like protein MFAP1 PF06991.11 ORY41676.1 - 0.026 14.4 26.2 0.043 13.7 26.2 1.4 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing SDA1 PF05285.12 ORY41676.1 - 0.092 12.2 24.1 0.1 12.0 24.1 1.1 1 0 0 1 1 1 0 SDA1 CDC27 PF09507.10 ORY41676.1 - 0.12 11.7 18.0 0.16 11.4 18.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.12 ORY41676.1 - 0.14 10.4 24.0 0.16 10.2 24.0 1.1 1 0 0 1 1 1 0 Nop14-like family SURF2 PF05477.11 ORY41676.1 - 0.31 10.7 13.4 0.43 10.2 13.4 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Nop53 PF07767.11 ORY41676.1 - 1.1 8.6 26.7 1.5 8.1 26.7 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SGT1 PF07093.11 ORY41676.1 - 1.3 7.3 11.5 1.7 7.0 11.5 1.2 1 0 0 1 1 1 0 SGT1 protein PA26 PF04636.13 ORY41676.1 - 1.4 7.8 3.6 1.6 7.5 3.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) FAM176 PF14851.6 ORY41676.1 - 2 8.0 17.1 4.4 7.0 17.1 1.6 1 0 0 1 1 1 0 FAM176 family SAPS PF04499.15 ORY41676.1 - 3.8 6.2 10.1 4.1 6.1 10.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein VIT1 PF01988.19 ORY41676.1 - 5 6.9 6.1 4.1 7.2 4.7 1.5 1 1 0 1 1 1 0 VIT family TFIIF_alpha PF05793.12 ORY41676.1 - 5.9 5.4 25.5 7.2 5.1 25.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_phi PF04931.13 ORY41676.1 - 8.4 4.4 33.6 9.7 4.1 33.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi BCS1_N PF08740.11 ORY41677.1 - 5.2e-36 124.4 0.0 8.5e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 ORY41677.1 - 6.2e-18 65.5 0.0 1e-17 64.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY41677.1 - 0.00037 20.5 0.0 0.0013 18.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY41677.1 - 0.00053 20.4 0.1 0.0024 18.3 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain DUF815 PF05673.13 ORY41677.1 - 0.0037 16.4 0.0 0.0054 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 ORY41677.1 - 0.0046 17.5 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ORY41677.1 - 0.0067 16.0 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region RuvB_N PF05496.12 ORY41677.1 - 0.0074 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_21 PF13304.6 ORY41677.1 - 0.0082 16.0 0.0 0.018 14.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY41677.1 - 0.012 15.4 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 ORY41677.1 - 0.017 15.0 0.1 0.47 10.4 0.0 2.4 1 1 1 2 2 2 0 NACHT domain AAA_28 PF13521.6 ORY41677.1 - 0.019 15.2 0.0 0.046 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY41677.1 - 0.025 14.3 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ORY41677.1 - 0.028 14.7 0.0 0.076 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORY41677.1 - 0.037 14.2 0.0 0.069 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 ORY41677.1 - 0.044 13.6 0.0 0.067 13.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ATPase PF06745.13 ORY41677.1 - 0.061 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 KaiC Rad17 PF03215.15 ORY41677.1 - 0.07 13.1 0.0 1.8 8.5 0.0 2.2 1 1 1 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 ORY41677.1 - 0.07 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 ORY41677.1 - 0.1 12.2 0.1 0.39 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 ORY41677.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ORY41677.1 - 0.12 12.9 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter TsaE PF02367.17 ORY41677.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 ORY41677.1 - 0.15 12.5 0.0 0.4 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ORY41677.1 - 0.21 12.1 0.0 0.43 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_6 PF12774.7 ORY41677.1 - 0.22 10.5 0.0 0.35 9.8 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Glycos_transf_1 PF00534.20 ORY41679.1 - 8.6e-09 35.2 0.0 4.8e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY41679.1 - 2.9e-05 24.5 0.0 5.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 LRR_8 PF13855.6 ORY41680.1 - 6.4e-33 112.3 18.3 1.9e-12 46.7 1.1 3.2 1 1 3 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 ORY41680.1 - 4.3e-19 68.3 13.9 5e-07 29.9 0.2 3.8 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY41680.1 - 7e-12 44.2 8.2 0.31 11.7 0.3 5.7 6 0 0 6 6 6 5 Leucine Rich Repeat LRR_6 PF13516.6 ORY41680.1 - 0.00011 22.0 5.9 2.8 8.2 0.1 5.3 5 0 0 5 5 5 1 Leucine Rich repeat LRR_9 PF14580.6 ORY41680.1 - 0.00059 19.4 0.2 0.66 9.5 0.1 2.4 1 1 1 2 2 2 2 Leucine-rich repeat Asp PF00026.23 ORY41681.1 - 7e-49 166.9 0.1 1.1e-47 163.0 0.1 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY41681.1 - 0.062 13.5 3.6 1.4 9.1 1.4 2.7 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal Glycos_transf_1 PF00534.20 ORY41682.1 - 1.8e-07 30.8 0.0 3.4e-06 26.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 TIR_2 PF13676.6 ORY41685.1 - 1.4e-09 38.6 0.0 0.0011 19.6 0.0 2.5 2 0 0 2 2 2 2 TIR domain TIR PF01582.20 ORY41685.1 - 0.006 16.4 0.3 0.032 14.0 0.0 2.3 3 0 0 3 3 3 1 TIR domain zf-C3HC4_3 PF13920.6 ORY41686.1 - 5.6e-09 35.7 6.2 1.1e-08 34.8 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY41686.1 - 1.7e-08 34.6 9.0 1.7e-08 34.6 9.0 2.1 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 ORY41686.1 - 2.2e-08 33.9 6.2 4.1e-08 33.0 6.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY41686.1 - 3.3e-06 26.8 9.1 1.6e-05 24.7 8.9 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 ORY41686.1 - 4.4e-06 26.4 7.6 4.4e-06 26.4 7.6 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY41686.1 - 4.6e-06 26.4 7.2 1.3e-05 25.0 7.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY41686.1 - 2.7e-05 24.1 5.6 6.7e-05 22.8 5.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 ORY41686.1 - 0.00063 19.4 1.9 0.00063 19.4 1.9 2.3 3 0 0 3 3 3 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 ORY41686.1 - 0.013 15.7 4.3 0.013 15.7 4.3 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FapA PF03961.13 ORY41686.1 - 0.015 14.0 4.3 0.02 13.5 4.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DZR PF12773.7 ORY41686.1 - 0.017 15.1 4.5 0.045 13.8 4.5 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-UDP PF14569.6 ORY41686.1 - 0.059 13.5 2.1 0.17 12.0 2.1 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 ORY41686.1 - 0.12 12.2 9.7 0.5 10.2 9.7 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 ORY41686.1 - 0.13 12.2 5.0 0.44 10.5 5.0 1.9 1 1 0 1 1 1 0 zf-RING of BARD1-type protein DUF1272 PF06906.11 ORY41686.1 - 0.29 11.3 4.8 0.81 9.8 4.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-rbx1 PF12678.7 ORY41686.1 - 1 9.7 12.8 0.17 12.2 8.1 2.2 3 0 0 3 3 2 0 RING-H2 zinc finger domain LMBR1 PF04791.16 ORY41686.1 - 2.6 6.8 4.7 3.3 6.5 4.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-P11 PF03854.14 ORY41686.1 - 6.5 6.5 10.2 2.3 8.0 5.9 2.1 2 0 0 2 2 2 0 P-11 zinc finger SNF2_N PF00176.23 ORY41687.1 - 9.5e-24 83.8 0.2 4e-23 81.7 0.2 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 ORY41687.1 - 1.4e-09 37.6 4.9 3.3e-09 36.5 4.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY41687.1 - 5.8e-09 35.8 3.8 1.2e-08 34.8 3.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 ORY41687.1 - 3.8e-08 33.5 6.6 1e-07 32.1 6.6 1.8 1 0 0 1 1 1 1 Ring finger domain ResIII PF04851.15 ORY41687.1 - 6.6e-08 32.7 0.3 6.6e-08 32.7 0.3 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_2 PF13923.6 ORY41687.1 - 1.8e-06 27.6 6.0 1.8e-06 27.6 6.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY41687.1 - 3.3e-06 26.8 4.2 8.2e-06 25.6 4.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY41687.1 - 3.3e-06 27.0 2.6 8e-06 25.8 2.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 ORY41687.1 - 0.00023 21.0 8.8 0.0013 18.5 8.7 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 ORY41687.1 - 0.0011 18.7 1.3 0.004 16.9 1.3 2.1 1 0 0 1 1 1 1 RING-like zinc finger TetR_N PF00440.23 ORY41687.1 - 0.0087 15.8 0.1 6.1 6.7 0.0 2.5 2 0 0 2 2 2 2 Bacterial regulatory proteins, tetR family zf-RING_6 PF14835.6 ORY41687.1 - 0.063 13.2 1.7 0.2 11.6 1.7 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Remorin_N PF03766.13 ORY41687.1 - 0.069 13.2 1.0 0.23 11.5 1.0 1.9 1 0 0 1 1 1 0 Remorin, N-terminal region AAA_19 PF13245.6 ORY41687.1 - 0.089 13.1 0.0 0.24 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DZR PF12773.7 ORY41687.1 - 0.093 12.8 4.6 0.22 11.6 4.6 1.6 1 0 0 1 1 1 0 Double zinc ribbon SWI2_SNF2 PF18766.1 ORY41687.1 - 0.12 12.0 2.6 0.24 11.0 0.1 2.5 2 1 0 2 2 2 0 SWI2/SNF2 ATPase zf-C3HC4_4 PF15227.6 ORY41687.1 - 0.14 12.4 7.5 0.028 14.6 3.6 1.8 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 ORY41687.1 - 0.22 11.8 5.9 0.63 10.4 5.9 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 ORY41687.1 - 0.42 10.4 7.9 1.1 9.1 7.9 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 ORY41687.1 - 0.74 9.5 7.6 0.24 11.1 4.0 2.0 2 0 0 2 2 2 0 P-11 zinc finger zf-ribbon_3 PF13248.6 ORY41687.1 - 8.9 5.9 7.9 0.37 10.3 1.9 1.9 2 0 0 2 2 2 0 zinc-ribbon domain PIF1 PF05970.14 ORY41688.1 - 6.2e-05 22.3 0.1 8.1e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase SH3_13 PF18335.1 ORY41688.1 - 7.5e-05 22.5 0.0 0.00016 21.4 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain EF1_GNE PF00736.19 ORY41689.1 - 1.2e-33 115.1 0.6 1.2e-33 115.1 0.6 1.8 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 ORY41689.1 - 5.6e-11 42.7 7.5 5.6e-11 42.7 7.5 2.8 4 0 0 4 4 4 1 Eukaryotic elongation factor 1 beta central acidic region MinC_N PF05209.13 ORY41689.1 - 0.077 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain Glyco_transf_90 PF05686.12 ORY41690.1 - 0.13 11.1 0.9 13 4.6 0.0 2.6 3 0 0 3 3 3 0 Glycosyl transferase family 90 Glyco_transf_90 PF05686.12 ORY41691.1 - 1.4e-19 70.3 1.1 1.4e-18 67.0 0.1 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 90 zf-C2HE PF16278.5 ORY41691.1 - 0.035 14.6 0.7 0.035 14.6 0.7 1.8 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger ribosomal_L24 PF17136.4 ORY41692.1 - 1.1e-11 45.0 0.1 1.9e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 ORY41692.1 - 0.095 12.7 5.9 1.7 8.7 5.9 2.4 1 1 0 1 1 1 0 KOW motif Vta1 PF04652.16 ORY41693.1 - 9.3e-51 171.6 0.3 1.3e-50 171.2 0.3 1.2 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 ORY41693.1 - 2.3e-17 62.4 0.6 2.3e-17 62.4 0.6 2.1 2 0 0 2 2 2 1 Vta1 C-terminal domain TRM PF02005.16 ORY41694.1 - 2e-127 425.5 0.0 2.5e-127 425.2 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase DUF4470 PF14737.6 ORY41695.1 - 4.4e-16 58.8 0.0 6.2e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) DUF4471 PF14740.6 ORY41696.1 - 2.2e-07 30.4 0.0 2.2e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4471) ALG11_N PF15924.5 ORY41697.1 - 7.8e-63 212.3 0.1 2.3e-62 210.8 0.1 1.7 1 1 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 ORY41697.1 - 1.5e-19 70.2 0.0 3.2e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY41697.1 - 3.3e-11 43.7 0.0 1.2e-10 41.9 0.0 2.0 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORY41697.1 - 0.0038 17.2 0.0 0.0075 16.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 ORY41697.1 - 0.0089 16.4 0.0 0.021 15.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Flavodoxin_NdrI PF07972.11 ORY41697.1 - 0.078 13.2 0.0 0.21 11.8 0.0 1.8 1 0 0 1 1 1 0 NrdI Flavodoxin like Mito_carr PF00153.27 ORY41698.1 - 2.9e-29 100.9 0.1 1e-15 57.4 0.0 2.1 1 1 1 2 2 2 2 Mitochondrial carrier protein bZIP_1 PF00170.21 ORY41699.1 - 9e-06 25.7 12.8 0.005 16.9 0.2 2.1 2 0 0 2 2 2 2 bZIP transcription factor SIKE PF05769.11 ORY41699.1 - 0.00018 21.5 1.0 0.00028 20.9 1.0 1.3 1 0 0 1 1 1 1 SIKE family bZIP_2 PF07716.15 ORY41699.1 - 0.00042 20.3 11.5 0.021 14.9 0.8 2.1 1 1 1 2 2 2 2 Basic region leucine zipper SOGA PF11365.8 ORY41699.1 - 0.0012 19.9 2.5 0.0016 19.6 2.5 1.2 1 0 0 1 1 1 1 Protein SOGA TSC22 PF01166.18 ORY41699.1 - 0.0022 18.3 0.5 0.025 14.9 0.2 2.5 2 1 0 2 2 2 1 TSC-22/dip/bun family Spc29 PF17082.5 ORY41699.1 - 0.0029 17.5 0.5 0.0034 17.3 0.5 1.2 1 0 0 1 1 1 1 Spindle Pole Component 29 PRKG1_interact PF15898.5 ORY41699.1 - 0.0075 17.2 4.8 0.0098 16.8 4.8 1.2 1 0 0 1 1 1 1 cGMP-dependent protein kinase interacting domain Shugoshin_N PF07558.11 ORY41699.1 - 0.037 13.9 0.1 0.037 13.9 0.1 2.3 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Atg14 PF10186.9 ORY41699.1 - 0.056 12.5 5.1 0.075 12.1 5.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 ORY41699.1 - 0.062 13.4 3.8 0.076 13.1 3.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus GIT_CC PF16559.5 ORY41699.1 - 0.072 13.0 2.1 0.13 12.1 2.1 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor NolV PF06635.12 ORY41699.1 - 0.093 12.1 2.2 0.12 11.7 2.2 1.1 1 0 0 1 1 1 0 Nodulation protein NolV Jnk-SapK_ap_N PF09744.9 ORY41699.1 - 0.11 12.7 8.2 0.13 12.5 8.2 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 HAUS6_N PF14661.6 ORY41699.1 - 0.13 11.9 3.4 0.14 11.8 3.4 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus OrfB_IS605 PF01385.19 ORY41699.1 - 0.13 12.4 1.1 0.2 11.9 1.1 1.3 1 0 0 1 1 1 0 Probable transposase DUF5539 PF17693.1 ORY41699.1 - 0.15 11.7 1.8 0.2 11.3 1.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5539) Nnf1 PF03980.14 ORY41699.1 - 0.16 12.3 6.8 1 9.8 6.8 1.9 1 1 0 1 1 1 0 Nnf1 bZIP_Maf PF03131.17 ORY41699.1 - 0.74 10.4 10.1 1.1 9.8 10.1 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF4140 PF13600.6 ORY41699.1 - 2.4 8.6 8.2 82 3.7 8.2 2.1 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Cu-oxidase PF00394.22 ORY41700.1 - 2.2e-39 135.1 0.3 8.1e-38 130.0 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY41700.1 - 2.9e-29 101.5 8.5 2.2e-13 50.1 0.1 3.8 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORY41700.1 - 3e-20 72.4 8.8 2.1e-19 69.7 0.6 4.0 4 1 0 4 4 4 1 Multicopper oxidase bZIP_1 PF00170.21 ORY41701.1 - 2e-06 27.8 10.9 6.2e-05 23.0 10.9 2.2 1 1 0 1 1 1 1 bZIP transcription factor Rootletin PF15035.6 ORY41701.1 - 0.00067 19.7 1.9 0.00075 19.6 1.9 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion Dynamitin PF04912.14 ORY41701.1 - 0.0011 18.4 1.3 0.0013 18.1 1.3 1.2 1 0 0 1 1 1 1 Dynamitin HOOK PF05622.12 ORY41701.1 - 0.0039 15.4 1.7 0.0047 15.2 1.7 1.1 1 0 0 1 1 1 1 HOOK protein bZIP_2 PF07716.15 ORY41701.1 - 0.012 15.7 8.4 0.23 11.5 0.9 2.3 2 0 0 2 2 2 0 Basic region leucine zipper SOGA PF11365.8 ORY41701.1 - 0.028 15.5 3.9 0.044 14.9 3.3 1.6 1 1 0 1 1 1 0 Protein SOGA YabA PF06156.13 ORY41701.1 - 0.045 14.4 1.5 0.064 13.9 1.5 1.3 1 0 0 1 1 1 0 Initiation control protein YabA HALZ PF02183.18 ORY41701.1 - 0.045 14.0 0.7 0.09 13.0 0.7 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper KASH_CCD PF14662.6 ORY41701.1 - 0.061 13.1 5.4 0.081 12.8 5.4 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH BRE1 PF08647.11 ORY41701.1 - 0.12 12.5 4.8 0.16 12.0 4.8 1.2 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Macoilin PF09726.9 ORY41701.1 - 0.26 9.8 6.4 0.28 9.7 6.4 1.0 1 0 0 1 1 1 0 Macoilin family bZIP_Maf PF03131.17 ORY41701.1 - 0.68 10.5 10.4 0.074 13.6 5.0 1.9 1 1 1 2 2 2 0 bZIP Maf transcription factor ZapB PF06005.12 ORY41701.1 - 1.8 9.1 9.1 2 8.9 7.8 1.8 1 1 0 1 1 1 0 Cell division protein ZapB DivIC PF04977.15 ORY41701.1 - 2.1 8.2 6.0 0.75 9.6 1.1 2.1 1 1 1 2 2 2 0 Septum formation initiator Glutaredoxin2_C PF04399.13 ORY41704.1 - 0.0069 16.2 0.2 0.011 15.5 0.2 1.4 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain bZIP_1 PF00170.21 ORY41704.1 - 0.081 13.0 3.2 0.18 11.9 3.2 1.5 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 ORY41704.1 - 2.8 8.1 14.9 0.063 13.4 7.7 1.8 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_2 PF07716.15 ORY41705.1 - 6.2e-05 23.0 7.7 0.00015 21.7 7.7 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 ORY41705.1 - 0.00024 21.1 9.7 0.0011 19.1 9.7 2.0 1 1 0 1 1 1 1 bZIP transcription factor ketoacyl-synt PF00109.26 ORY41705.1 - 0.4 10.2 2.1 1.3 8.5 0.4 2.0 1 1 1 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain bZIP_Maf PF03131.17 ORY41706.1 - 0.00048 20.6 5.8 0.00099 19.6 5.8 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 ORY41706.1 - 0.0013 18.8 10.9 0.0031 17.6 10.9 1.7 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY41706.1 - 0.38 10.9 22.2 0.11 12.7 17.4 2.4 2 1 0 2 2 2 0 Basic region leucine zipper ketoacyl-synt PF00109.26 ORY41706.1 - 0.67 9.5 2.0 1.7 8.2 0.5 1.9 1 1 1 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain bZIP_1 PF00170.21 ORY41707.1 - 4.8e-06 26.6 8.1 8.4e-06 25.8 8.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY41707.1 - 0.0012 18.9 9.8 0.0019 18.3 9.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper Glutaredoxin2_C PF04399.13 ORY41707.1 - 0.014 15.2 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain MRP-S26 PF14943.6 ORY41707.1 - 0.044 13.7 2.6 0.071 13.0 2.6 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 Dynactin_p22 PF07426.11 ORY41708.1 - 0.024 14.5 0.1 0.034 14.0 0.1 1.2 1 0 0 1 1 1 0 Dynactin subunit p22 Ada3 PF10198.9 ORY41708.1 - 0.034 14.3 0.1 0.043 14.0 0.1 1.1 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 DUF5578 PF17741.1 ORY41709.1 - 0.069 12.6 0.3 0.13 11.7 0.1 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5578) bZIP_1 PF00170.21 ORY41710.1 - 1.4e-07 31.5 3.3 1.4e-07 31.5 3.3 3.5 3 1 0 3 3 3 2 bZIP transcription factor bZIP_2 PF07716.15 ORY41710.1 - 0.00048 20.1 16.3 0.027 14.6 2.6 3.5 3 0 0 3 3 3 3 Basic region leucine zipper bZIP_Maf PF03131.17 ORY41710.1 - 0.004 17.7 8.5 0.035 14.6 4.1 2.9 2 1 1 3 3 3 1 bZIP Maf transcription factor TSC22 PF01166.18 ORY41710.1 - 0.0082 16.4 4.2 0.51 10.7 0.1 3.3 3 0 0 3 3 3 2 TSC-22/dip/bun family zf-C4pol PF14260.6 ORY41710.1 - 0.78 10.3 3.9 0.92 10.0 1.6 2.2 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta HutD PF05962.11 ORY41711.1 - 1.2e-35 123.2 0.0 1.4e-35 123.0 0.0 1.1 1 0 0 1 1 1 1 HutD bZIP_1 PF00170.21 ORY41712.1 - 4.1e-11 42.8 17.1 9e-11 41.7 6.9 3.1 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 ORY41712.1 - 1.2e-06 28.5 6.8 1.2e-06 28.5 6.8 3.4 3 1 0 3 3 3 2 Basic region leucine zipper DUF2721 PF11026.8 ORY41712.1 - 0.02 14.8 1.3 0.02 14.8 1.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) BLOC1_2 PF10046.9 ORY41712.1 - 0.057 13.7 7.3 2.4 8.5 1.3 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UPF0242 PF06785.11 ORY41712.1 - 0.073 13.2 15.0 0.13 12.4 1.1 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1380 PF07128.12 ORY41712.1 - 0.19 11.9 2.7 1.4 9.1 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1380) BRE1 PF08647.11 ORY41712.1 - 1.1 9.4 15.4 0.22 11.6 9.2 2.1 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF724 PF05266.14 ORY41712.1 - 3.5 7.4 12.7 0.5 10.2 7.3 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF724) bZIP_1 PF00170.21 ORY41713.1 - 1.3e-07 31.6 8.6 4.5e-07 29.9 4.1 2.4 2 0 0 2 2 2 1 bZIP transcription factor Nop53 PF07767.11 ORY41713.1 - 0.0059 16.0 1.4 0.0099 15.3 1.4 1.3 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) CENP-F_leu_zip PF10473.9 ORY41713.1 - 0.035 14.1 5.2 0.11 12.5 0.1 2.4 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FAM199X PF15814.5 ORY41713.1 - 0.15 11.1 2.9 0.23 10.5 2.9 1.2 1 0 0 1 1 1 0 Protein family FAM199X IATP PF04568.12 ORY41713.1 - 0.2 12.1 0.2 0.2 12.1 0.2 2.4 3 0 0 3 3 3 0 Mitochondrial ATPase inhibitor, IATP Sugarporin_N PF11471.8 ORY41713.1 - 0.37 10.8 4.2 3.7 7.6 0.1 3.2 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension bZIP_2 PF07716.15 ORY41713.1 - 0.68 10.1 11.6 0.15 12.2 2.2 2.8 3 0 0 3 3 3 0 Basic region leucine zipper Spc24 PF08286.11 ORY41713.1 - 4 7.7 6.2 12 6.2 0.1 2.8 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Npa1 PF11707.8 ORY41714.1 - 0.012 15.0 0.6 0.019 14.4 0.2 1.4 1 1 0 1 1 1 0 Ribosome 60S biogenesis N-terminal DUF5388 PF17363.2 ORY41714.1 - 0.026 14.7 0.1 0.042 14.1 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5388) IMP_cyclohyd PF07826.11 ORY41714.1 - 0.065 12.8 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein Gluconate_2-dh3 PF13618.6 ORY41714.1 - 0.082 13.1 0.0 0.23 11.7 0.0 1.6 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Paramyxo_C PF01692.18 ORY41714.1 - 0.17 11.2 2.2 0.45 9.9 1.0 1.8 1 1 1 2 2 2 0 Paramyxovirus non-structural protein C Conotoxin PF02950.17 ORY41715.1 - 2.5 9.2 7.8 11 7.1 0.5 2.7 3 0 0 3 3 3 0 Conotoxin bZIP_1 PF00170.21 ORY41718.1 - 0.049 13.7 1.4 0.1 12.7 1.4 1.5 1 0 0 1 1 1 0 bZIP transcription factor UPF0183 PF03676.14 ORY41719.1 - 0.087 12.1 0.3 0.13 11.5 0.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0183) LamB_YcsF PF03746.16 ORY41720.1 - 0.015 15.0 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 LamB/YcsF family zf-C2H2_4 PF13894.6 ORY41721.1 - 0.0014 19.3 17.6 0.011 16.6 1.1 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY41721.1 - 0.0039 17.6 1.3 0.0039 17.6 1.3 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.7 ORY41721.1 - 0.01 16.2 3.9 0.02 15.3 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 ORY41721.1 - 0.024 14.4 7.4 0.16 11.8 1.5 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-HIT PF04438.16 ORY41721.1 - 0.024 14.5 10.5 0.063 13.2 4.2 2.4 2 0 0 2 2 2 0 HIT zinc finger Zn-C2H2_12 PF18112.1 ORY41721.1 - 0.17 12.4 2.2 6 7.4 0.0 2.7 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf_UBZ PF18439.1 ORY41721.1 - 0.34 10.5 3.0 4.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_5 PF13719.6 ORY41721.1 - 0.64 9.8 5.7 11 5.8 0.2 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_6 PF13912.6 ORY41721.1 - 3.5 7.7 11.2 1.4 9.0 0.3 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger DZR PF12773.7 ORY41721.1 - 4.5 7.4 10.9 32 4.7 10.9 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_9 PF16293.5 ORY41721.1 - 4.5 7.2 7.0 2.5 8.0 0.0 3.2 4 0 0 4 4 3 0 C2H2 type zinc-finger (1 copy) Zn-ribbon_8 PF09723.10 ORY41721.1 - 4.6 7.4 8.7 17 5.6 0.1 2.8 2 1 0 2 2 2 0 Zinc ribbon domain zf_C2H2_6 PF18450.1 ORY41721.1 - 8.2 6.2 9.1 4 7.2 0.5 2.7 2 0 0 2 2 2 0 Zinc Finger domain XPA_N PF01286.18 ORY41721.1 - 9.2 6.4 8.4 14 5.8 0.4 2.7 3 0 0 3 3 3 0 XPA protein N-terminal DBP PF12361.8 ORY41723.1 - 0.09 12.6 2.1 0.15 11.9 2.1 1.3 1 0 0 1 1 1 0 Duffy-antigen binding protein TBD PF12845.7 ORY41723.1 - 0.28 11.1 1.4 1.8 8.5 0.1 2.3 1 1 1 2 2 2 0 TBD domain LRR_8 PF13855.6 ORY41724.1 - 8.5e-28 95.9 43.6 3.9e-09 36.2 2.8 6.0 4 1 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 ORY41724.1 - 9.4e-22 76.7 40.9 0.00015 22.0 1.9 7.2 5 1 3 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY41724.1 - 1e-10 40.6 34.1 2.5 9.0 0.1 11.8 12 0 0 12 12 12 5 Leucine Rich Repeat LRR_6 PF13516.6 ORY41724.1 - 5.3e-05 22.9 32.6 1.7 8.9 0.0 10.6 11 0 0 11 11 11 3 Leucine Rich repeat TSC22 PF01166.18 ORY41725.1 - 0.0026 18.0 3.2 4.1 7.8 0.1 3.4 3 0 0 3 3 3 2 TSC-22/dip/bun family YobH PF13996.6 ORY41725.1 - 0.14 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 YobH-like protein bZIP_1 PF00170.21 ORY41725.1 - 0.21 11.7 11.7 0.44 10.7 0.9 3.1 3 1 1 4 4 4 0 bZIP transcription factor ABC_tran_CTD PF16326.5 ORY41725.1 - 2.3 8.6 4.0 5 7.4 2.0 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain Acyl_transf_3 PF01757.22 ORY41726.1 - 0.06 12.4 0.2 0.069 12.2 0.2 1.1 1 0 0 1 1 1 0 Acyltransferase family Transferase PF02458.15 ORY41727.1 - 1.8e-08 33.5 0.0 2.2e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Transferase family bZIP_Maf PF03131.17 ORY41728.1 - 0.013 16.0 6.1 0.016 15.8 6.1 1.1 1 0 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 ORY41728.1 - 0.08 13.0 11.8 0.13 12.4 11.8 1.3 1 0 0 1 1 1 0 Basic region leucine zipper NeA_P2 PF12312.8 ORY41728.1 - 0.16 11.4 0.9 0.19 11.2 0.9 1.1 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein DivIC PF04977.15 ORY41728.1 - 0.17 11.7 2.1 0.26 11.1 2.1 1.3 1 0 0 1 1 1 0 Septum formation initiator bZIP_1 PF00170.21 ORY41728.1 - 0.49 10.5 12.5 1.7 8.8 12.5 1.8 1 1 0 1 1 1 0 bZIP transcription factor Beta-lactamase PF00144.24 ORY41729.1 - 5.4e-43 147.5 0.0 7.7e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 ORY41729.1 - 0.00041 20.8 0.0 0.0011 19.5 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3471) IlvN PF07991.12 ORY41729.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain bZIP_1 PF00170.21 ORY41730.1 - 0.00016 21.7 10.4 0.00019 21.5 1.9 3.0 3 0 0 3 3 3 2 bZIP transcription factor bZIP_2 PF07716.15 ORY41730.1 - 0.014 15.5 4.1 0.014 15.5 4.1 2.4 3 0 0 3 3 3 0 Basic region leucine zipper DUF5094 PF17015.5 ORY41730.1 - 0.11 12.5 1.2 0.46 10.6 1.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5094) DUF2058 PF09831.9 ORY41730.1 - 0.69 10.0 6.7 0.89 9.7 6.5 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Gp_dh_C PF02800.20 ORY41731.1 - 0.19 11.3 0.1 0.79 9.3 0.1 1.9 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Methyltransf_4 PF02390.17 ORY41732.1 - 0.066 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase BppL_N PF18338.1 ORY41732.1 - 1.1 9.2 6.0 2.9 7.8 6.0 1.7 1 0 0 1 1 1 0 Lower baseplate protein N-terminal domain bZIP_1 PF00170.21 ORY41733.1 - 6.9e-12 45.3 10.4 1.3e-07 31.6 0.2 3.3 3 0 0 3 3 3 3 bZIP transcription factor bZIP_2 PF07716.15 ORY41733.1 - 1.8e-06 27.9 10.0 0.0026 17.8 2.0 3.3 2 1 1 3 3 3 2 Basic region leucine zipper TSC22 PF01166.18 ORY41733.1 - 0.00065 20.0 1.6 0.83 10.0 0.2 2.6 2 0 0 2 2 2 2 TSC-22/dip/bun family ABC_tran_CTD PF16326.5 ORY41733.1 - 0.001 19.2 0.8 1.5 9.2 0.1 3.2 2 1 1 3 3 3 2 ABC transporter C-terminal domain HALZ PF02183.18 ORY41733.1 - 0.0012 19.0 9.7 0.12 12.7 1.0 3.2 3 0 0 3 3 3 2 Homeobox associated leucine zipper LRRFIP PF09738.9 ORY41733.1 - 0.0027 17.2 0.8 0.0039 16.7 0.8 1.2 1 0 0 1 1 1 1 LRRFIP family Lebercilin PF15619.6 ORY41733.1 - 0.0038 16.9 7.6 0.13 11.9 0.8 2.2 2 0 0 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease Herpes_BLRF2 PF05812.12 ORY41733.1 - 0.012 15.8 1.3 0.041 14.0 0.0 2.4 3 0 0 3 3 2 0 Herpesvirus BLRF2 protein DivIC PF04977.15 ORY41733.1 - 0.018 14.8 5.1 0.53 10.1 0.1 3.2 2 1 1 3 3 3 0 Septum formation initiator Ubiq_cyt_C_chap PF03981.12 ORY41733.1 - 0.061 13.4 0.3 0.58 10.2 0.1 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome C chaperone CCDC144C PF14915.6 ORY41733.1 - 0.066 12.3 5.1 0.58 9.2 0.9 2.1 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region UPF0242 PF06785.11 ORY41733.1 - 0.069 13.2 5.3 0.17 12.0 2.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 ORY41733.1 - 0.088 13.0 9.7 1.8 8.7 1.3 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 ORY41733.1 - 0.1 12.6 5.0 0.42 10.6 5.0 1.9 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fungal_TACC PF12709.7 ORY41733.1 - 0.13 12.7 2.5 14 6.2 0.4 2.5 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins K-box PF01486.17 ORY41733.1 - 0.15 12.3 3.7 1.2 9.3 0.7 2.5 2 1 0 2 2 2 0 K-box region TPR_MLP1_2 PF07926.12 ORY41733.1 - 0.3 11.2 6.9 0.3 11.1 4.8 1.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CLZ PF16526.5 ORY41733.1 - 0.4 11.1 5.8 5.4 7.5 0.9 2.6 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels YabA PF06156.13 ORY41733.1 - 0.49 11.1 3.5 12 6.6 0.6 2.3 1 1 0 2 2 2 0 Initiation control protein YabA Csm1_N PF18504.1 ORY41733.1 - 0.63 10.4 6.3 3.7 8.0 0.7 3.1 2 1 0 3 3 3 0 Csm1 N-terminal domain KLRAQ PF10205.9 ORY41733.1 - 0.71 10.1 4.1 5.4 7.3 0.6 2.4 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Shugoshin_N PF07558.11 ORY41733.1 - 0.77 9.7 8.7 0.7 9.8 4.6 2.5 2 1 0 2 2 2 0 Shugoshin N-terminal coiled-coil region GAS PF13851.6 ORY41733.1 - 1.2 8.5 6.6 7.2 5.9 0.5 2.2 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.6 ORY41733.1 - 1.2 9.3 6.6 5.3 7.2 0.9 3.1 3 0 0 3 3 2 0 Centrosome localisation domain of PPC89 ZapB PF06005.12 ORY41733.1 - 1.3 9.6 5.7 19 5.8 0.4 2.7 2 1 0 2 2 2 0 Cell division protein ZapB Nnf1 PF03980.14 ORY41733.1 - 1.6 9.2 6.4 3.7 8.0 4.3 2.5 1 1 1 2 2 2 0 Nnf1 DUF4140 PF13600.6 ORY41733.1 - 2.4 8.6 5.0 87 3.6 5.0 2.6 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.11 ORY41733.1 - 5.5 7.3 5.7 8 6.8 1.9 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 SlyX PF04102.12 ORY41733.1 - 9.7 6.9 7.1 54 4.5 0.2 3.4 3 1 0 3 3 3 0 SlyX LRR_8 PF13855.6 ORY41734.1 - 9.2e-15 54.2 25.0 1.4e-06 28.0 2.3 4.6 4 1 1 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 ORY41734.1 - 5.9e-08 32.9 30.9 0.016 15.6 6.8 4.7 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY41734.1 - 0.32 11.7 33.0 3.4 8.6 1.1 7.7 3 2 3 6 6 6 0 Leucine Rich Repeat Protoglobin PF11563.8 ORY41736.1 - 1.9e-41 141.6 0.1 2.3e-41 141.3 0.1 1.1 1 0 0 1 1 1 1 Protoglobin UPF0183 PF03676.14 ORY41737.1 - 5.8e-52 177.3 0.0 9.7e-52 176.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) Glycos_transf_1 PF00534.20 ORY41737.1 - 2.4e-08 33.7 0.0 5.6e-08 32.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY41737.1 - 4.8e-06 27.1 0.0 1.1e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 KH_9 PF17904.1 ORY41738.1 - 0.039 14.3 0.3 0.05 14.0 0.3 1.2 1 0 0 1 1 1 0 FMRP KH0 domain PLL PF18587.1 ORY41738.1 - 0.045 13.9 0.4 0.055 13.6 0.4 1.1 1 0 0 1 1 1 0 PTX/LNS-Like (PLL) domain Sensor_TM1 PF13755.6 ORY41742.1 - 0.067 12.9 0.2 0.067 12.9 0.2 1.6 2 0 0 2 2 2 0 Sensor N-terminal transmembrane domain PDR_assoc PF08370.11 ORY41743.1 - 1.6 8.5 6.5 8.1 6.3 0.7 2.2 1 1 1 2 2 2 0 Plant PDR ABC transporter associated DSPc PF00782.20 ORY41744.1 - 1.2e-11 44.6 0.0 2e-11 43.8 0.0 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 ORY41744.1 - 0.16 12.3 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain LRR_8 PF13855.6 ORY41745.1 - 4e-24 84.1 18.9 7.4e-09 35.2 4.2 4.5 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY41745.1 - 5.9e-16 58.3 24.3 0.00032 21.0 0.8 5.6 4 1 0 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY41745.1 - 8.2e-07 28.7 25.7 0.1 13.2 0.7 8.8 6 1 3 9 9 9 3 Leucine Rich Repeat F-box-like PF12937.7 ORY41745.1 - 0.0016 18.3 0.2 0.0034 17.2 0.2 1.5 1 0 0 1 1 1 1 F-box-like PHF12_MRG_bd PF16737.5 ORY41745.1 - 0.021 14.5 0.9 0.04 13.7 0.9 1.4 1 0 0 1 1 1 0 PHD finger protein 12 MRG binding domain LRR_6 PF13516.6 ORY41745.1 - 0.13 12.3 25.7 1.4 9.2 0.8 6.9 7 0 0 7 7 7 0 Leucine Rich repeat LRR_8 PF13855.6 ORY41746.1 - 0.0003 20.5 0.8 0.0069 16.1 1.1 2.5 1 1 2 3 3 3 3 Leucine rich repeat F-box-like PF12937.7 ORY41746.1 - 0.00033 20.5 0.1 0.0008 19.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY41746.1 - 0.0024 17.7 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.33 ORY41746.1 - 0.0038 17.6 0.4 10 7.1 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_4 PF12799.7 ORY41746.1 - 0.018 15.5 0.8 0.28 11.7 0.2 2.5 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY41746.1 - 0.028 14.5 0.9 14 6.1 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeat Mannosyl_trans2 PF04188.13 ORY41832.1 - 0.016 14.5 0.1 0.018 14.4 0.1 1.2 1 0 0 1 1 1 0 Mannosyltransferase (PIG-V) Gemini_coat PF00844.18 ORY41833.1 - 0.022 14.2 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Geminivirus coat protein/nuclear export factor BR1 family Peptidase_S8 PF00082.22 ORY41834.1 - 3e-35 121.9 4.5 5e-35 121.2 4.5 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 ORY41834.1 - 0.00074 20.2 6.5 0.058 14.1 6.5 2.6 1 1 0 1 1 1 1 Fn3-like domain PA PF02225.22 ORY41834.1 - 0.042 13.9 1.5 0.079 13.0 0.4 2.1 1 1 1 2 2 2 0 PA domain fn3_3 PF14686.6 ORY41834.1 - 0.17 11.7 1.5 1.4 8.8 0.1 3.1 3 0 0 3 3 3 0 Polysaccharide lyase family 4, domain II Solute_trans_a PF03619.16 ORY41835.1 - 1.4e-31 110.0 16.9 9.1e-27 94.2 9.0 2.0 1 1 1 2 2 2 2 Organic solute transporter Ostalpha FA_hydroxylase PF04116.13 ORY41839.1 - 9.5e-18 64.8 17.8 9.5e-18 64.8 17.8 1.8 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily EST1_DNA_bind PF10373.9 ORY41840.1 - 1.7e-17 63.8 2.8 4.1e-14 52.7 1.6 3.4 1 1 0 2 2 2 2 Est1 DNA/RNA binding domain EST1 PF10374.9 ORY41840.1 - 9.7e-12 45.7 0.1 9.7e-12 45.7 0.1 2.7 3 0 0 3 3 3 1 Telomerase activating protein Est1 PIN_4 PF13638.6 ORY41840.1 - 0.00015 22.0 0.0 0.00046 20.5 0.0 1.9 1 0 0 1 1 1 1 PIN domain DPBB_1 PF03330.18 ORY41841.1 - 0.0048 17.2 2.9 0.057 13.7 0.1 2.7 1 1 1 2 2 2 1 Lytic transglycolase Menin PF05053.13 ORY41841.1 - 0.11 10.8 5.5 0.15 10.4 5.5 1.1 1 0 0 1 1 1 0 Menin TFIIA PF03153.13 ORY41841.1 - 0.99 9.3 8.5 1.2 9.0 8.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC84 PF14968.6 ORY41841.1 - 5.4 6.5 7.1 7.5 6.1 7.1 1.1 1 0 0 1 1 1 0 Coiled coil protein 84 DPBB_1 PF03330.18 ORY41842.1 - 0.023 15.0 0.6 0.063 13.6 0.0 2.1 2 0 0 2 2 2 0 Lytic transglycolase PHC2_SAM_assoc PF16616.5 ORY41842.1 - 3.1 8.6 11.3 5 8.0 10.8 1.6 1 1 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Macoilin PF09726.9 ORY41842.1 - 7 5.1 5.7 8.7 4.8 5.7 1.1 1 0 0 1 1 1 0 Macoilin family Cytochrom_B558a PF05038.13 ORY41845.1 - 0.00045 19.8 1.3 0.00045 19.8 1.3 2.1 1 1 1 2 2 2 2 Cytochrome Cytochrome b558 alpha-subunit UQ_con PF00179.26 ORY41846.1 - 3.2e-44 150.0 0.1 3.5e-44 149.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 ORY41846.1 - 0.0001 22.2 0.1 0.00016 21.5 0.1 1.3 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 ORY41846.1 - 0.0042 17.4 0.0 0.0059 16.9 0.0 1.2 1 0 0 1 1 1 1 RWD domain Pex14_N PF04695.13 ORY41847.1 - 0.8 10.3 9.8 0.87 10.2 9.8 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CYSTM PF12734.7 ORY41847.1 - 3 8.2 78.0 25 5.3 56.4 4.7 1 1 0 2 2 2 0 Cysteine-rich TM module stress tolerance DUF2781 PF10914.8 ORY41848.1 - 7.8e-33 114.0 12.6 8.7e-33 113.8 12.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DsbD PF02683.15 ORY41848.1 - 0.014 15.3 0.4 0.02 14.8 0.4 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region DUF2569 PF10754.9 ORY41848.1 - 0.38 11.2 6.1 0.6 10.6 5.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) DUF2781 PF10914.8 ORY41849.1 - 2.7e-31 109.0 16.6 3e-31 108.8 16.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) GlpM PF06942.12 ORY41849.1 - 0.78 10.2 8.5 0.27 11.6 4.6 2.0 1 1 1 2 2 2 0 GlpM protein DUF2781 PF10914.8 ORY41850.1 - 6.8e-32 110.9 10.3 7.8e-32 110.7 10.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DUF3923 PF13061.6 ORY41850.1 - 0.12 12.5 0.2 0.12 12.5 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3923) Gemini_coat PF00844.18 ORY41851.1 - 0.01 15.3 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Geminivirus coat protein/nuclear export factor BR1 family Ion_trans PF00520.31 ORY41852.1 - 9.2e-10 38.2 5.1 1.4e-09 37.6 5.1 1.3 1 0 0 1 1 1 1 Ion transport protein Ank_3 PF13606.6 ORY41852.1 - 6.6e-09 35.3 0.2 0.071 13.7 0.0 6.0 7 0 0 7 7 7 2 Ankyrin repeat Ank_4 PF13637.6 ORY41852.1 - 5.2e-08 33.3 0.0 0.017 15.7 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY41852.1 - 3e-07 30.9 0.0 0.0023 18.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) PKD_channel PF08016.12 ORY41852.1 - 1.9e-05 23.5 0.7 2.8e-05 23.0 0.7 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ank PF00023.30 ORY41852.1 - 0.00011 22.5 0.0 0.017 15.6 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 ORY41852.1 - 0.00022 21.4 0.2 1.7 9.1 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) cNMP_binding PF00027.29 ORY41854.1 - 2.5e-15 56.3 0.0 5.7e-15 55.2 0.0 1.6 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain PGA2 PF07543.12 ORY41856.1 - 0.17 11.9 0.0 0.22 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 Tmemb_170 PF10190.9 ORY41857.1 - 0.0026 18.1 0.2 0.0026 18.1 0.2 1.5 2 0 0 2 2 2 1 Putative transmembrane protein 170 Ion_trans_2 PF07885.16 ORY41857.1 - 2 8.4 8.4 16 5.5 8.0 2.4 1 1 0 1 1 1 0 Ion channel PARG_cat PF05028.14 ORY41858.1 - 4.6e-06 26.2 0.0 6.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) MAPEG PF01124.18 ORY41860.1 - 9.3e-10 38.5 4.1 2.2e-09 37.3 3.9 1.8 1 1 0 1 1 1 1 MAPEG family DUF5325 PF17259.2 ORY41860.1 - 0.19 11.6 3.5 0.37 10.7 3.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5325) MAPEG PF01124.18 ORY41861.1 - 6.2e-22 77.9 1.3 7.6e-22 77.6 1.3 1.1 1 0 0 1 1 1 1 MAPEG family DUF4381 PF14316.6 ORY41861.1 - 0.014 15.6 0.1 0.044 14.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF4405 PF14358.6 ORY41861.1 - 1.5 9.4 8.9 16 6.1 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) PX PF00787.24 ORY41863.1 - 2.4e-09 37.2 0.1 3.4e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 ORY41864.1 - 0.00067 19.3 1.1 0.0065 16.1 0.1 2.3 2 1 0 2 2 2 1 Vps5 C terminal like DUF4795 PF16043.5 ORY41864.1 - 0.06 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4551 PF15087.6 ORY41864.1 - 0.09 11.6 1.8 0.098 11.5 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF4407 PF14362.6 ORY41864.1 - 0.9 8.8 3.7 0.21 10.9 0.8 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF3801 PF12687.7 ORY41864.1 - 6.3 6.8 7.5 11 6.0 7.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3801) DUF4448 PF14610.6 ORY41866.1 - 0.023 14.5 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Yos1 PF08571.10 ORY41867.1 - 1.9e-31 108.2 5.4 2.1e-31 108.0 5.4 1.0 1 0 0 1 1 1 1 Yos1-like DUF5083 PF16890.5 ORY41867.1 - 0.02 14.6 1.9 0.024 14.4 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) ArsC PF03960.15 ORY41867.1 - 0.039 14.0 0.0 0.059 13.4 0.0 1.2 1 0 0 1 1 1 0 ArsC family CDC45 PF02724.14 ORY41868.1 - 0.2 9.9 15.1 0.23 9.7 15.1 1.1 1 0 0 1 1 1 0 CDC45-like protein TrmO PF01980.16 ORY41869.1 - 5.6e-38 129.8 0.0 1.2e-37 128.7 0.0 1.6 1 0 0 1 1 1 1 tRNA-methyltransferase O TrmO_C PF18389.1 ORY41869.1 - 0.045 13.9 0.0 0.17 12.0 0.0 2.0 1 1 0 1 1 1 0 TrmO C-terminal domain CPL PF08144.11 ORY41870.1 - 5.6e-26 91.6 11.3 2.6e-25 89.4 0.1 4.7 3 3 2 5 5 5 1 CPL (NUC119) domain DUF2441 PF10386.9 ORY41870.1 - 0.048 13.7 0.0 0.33 10.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2441) DUF4541 PF15074.6 ORY41870.1 - 0.3 11.7 2.1 5.1 7.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4541) zf-ANAPC11 PF12861.7 ORY41872.1 - 1.6e-34 117.9 7.9 1.9e-34 117.6 7.9 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 ORY41872.1 - 5.7e-18 65.0 7.0 8.2e-18 64.4 7.0 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ORY41872.1 - 0.0025 17.8 8.3 0.0042 17.1 8.3 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 ORY41872.1 - 0.0028 17.9 13.4 0.048 14.0 13.3 2.3 1 1 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 ORY41872.1 - 0.0086 15.7 5.3 0.0086 15.7 5.3 1.8 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 ORY41872.1 - 0.08 12.7 11.9 1.2 9.0 11.9 2.2 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4 PF00097.25 ORY41872.1 - 0.17 11.8 9.8 0.73 9.8 9.8 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY41872.1 - 3.4 7.7 14.0 29 4.7 14.5 2.3 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ORY41872.1 - 6.4 6.7 14.2 31 4.5 14.2 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MutS_V PF00488.21 ORY41873.1 - 1.3e-38 132.9 0.0 2.1e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORY41873.1 - 3.2e-05 24.3 0.1 7.9e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 ORY41873.1 - 0.0002 21.6 0.0 0.0005 20.4 0.0 1.7 2 0 0 2 2 2 1 MutS family domain IV Y_phosphatase PF00102.27 ORY41874.1 - 1.2e-06 28.3 0.0 1.7e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 ORY41874.1 - 2.7e-06 27.2 0.0 3.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 ORY41874.1 - 0.0027 17.8 0.0 0.0039 17.3 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 ORY41874.1 - 0.014 15.1 0.2 0.056 13.1 0.1 2.0 2 1 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Rbsn PF11464.8 ORY41876.1 - 0.059 13.1 3.4 0.42 10.4 0.0 3.4 3 0 0 3 3 3 0 Rabenosyn Rab binding domain Chordopox_RPO7 PF05864.12 ORY41876.1 - 0.35 11.1 1.5 15 5.9 0.1 2.6 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) RapH_N PF18801.1 ORY41876.1 - 1.3 9.1 4.7 1.3 9.2 0.6 3.1 3 0 0 3 3 3 0 response regulator aspartate phosphatase H, N terminal Spc7 PF08317.11 ORY41876.1 - 4 6.2 33.0 2.2 7.1 10.2 3.2 1 1 1 3 3 3 0 Spc7 kinetochore protein PRESAN PF09687.10 ORY41876.1 - 6.7 7.3 12.5 0.12 12.9 3.7 2.5 2 1 1 3 3 3 0 Plasmodium RESA N-terminal Guanylate_cyc PF00211.20 ORY41877.1 - 3.7e-12 46.2 0.1 1.4e-06 28.1 0.0 2.6 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 ORY41877.1 - 2.4e-11 44.3 0.0 1.1e-10 42.1 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 ORY41877.1 - 0.0012 18.1 0.8 0.0058 15.8 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ATPase_2 PF01637.18 ORY41877.1 - 0.0026 17.7 0.1 0.096 12.6 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea T2SSE PF00437.20 ORY41877.1 - 0.0037 16.4 0.0 0.0074 15.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 ORY41877.1 - 0.0049 17.1 0.0 0.33 11.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain CofC PF01983.16 ORY41877.1 - 0.0054 15.9 0.0 0.012 14.8 0.0 1.6 1 0 0 1 1 1 1 Guanylyl transferase CofC like AAA_35 PF14516.6 ORY41877.1 - 0.012 14.5 0.0 0.028 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_7 PF12775.7 ORY41877.1 - 0.015 14.8 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 ORY41877.1 - 0.019 14.9 0.1 0.12 12.3 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 ORY41877.1 - 0.022 15.2 0.0 0.086 13.3 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA12 PF10443.9 ORY41877.1 - 0.04 12.6 0.2 0.089 11.5 0.0 1.6 2 0 0 2 2 2 0 RNA12 protein RsgA_GTPase PF03193.16 ORY41877.1 - 0.043 13.7 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase cobW PF02492.19 ORY41877.1 - 0.093 12.3 0.0 0.31 10.6 0.0 1.9 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 ORY41877.1 - 0.094 11.9 0.3 0.3 10.3 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.27 ORY41877.1 - 0.13 12.8 0.0 0.49 10.9 0.0 2.1 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.6 ORY41877.1 - 0.13 12.5 1.8 1.1 9.5 1.8 2.7 1 1 0 1 1 1 0 AAA domain Helicase_C PF00271.31 ORY41878.1 - 1e-27 96.7 0.1 3.1e-25 88.7 0.1 2.7 2 1 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 ORY41878.1 - 2.7e-25 89.2 2.0 2.9e-21 76.0 2.0 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ORY41878.1 - 2.4e-05 24.4 1.5 0.00036 20.6 0.1 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 ORY41878.1 - 0.0052 16.3 0.2 0.01 15.4 0.2 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain RNA_pol_Rpb4 PF03874.16 ORY41879.1 - 2.6e-16 60.1 1.6 3.5e-16 59.7 1.6 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb4 ABC_membrane PF00664.23 ORY41880.1 - 2.8e-37 128.9 32.0 1.7e-24 86.9 13.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY41880.1 - 7.4e-37 126.9 0.0 1.2e-29 103.6 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.6 ORY41880.1 - 0.00016 21.4 2.7 0.0068 16.1 0.3 2.9 3 0 0 3 3 3 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY41880.1 - 0.019 15.0 0.5 0.19 11.8 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 ORY41880.1 - 0.069 12.6 7.8 1.5 8.2 0.3 3.8 4 0 0 4 4 4 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY41880.1 - 0.07 13.5 0.0 6.2 7.2 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Sec2p PF06428.11 ORY41880.1 - 0.11 12.5 0.6 0.28 11.2 0.6 1.6 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p ATP-synt_ab PF00006.25 ORY41880.1 - 0.12 12.1 0.2 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.23 ORY41880.1 - 0.35 10.9 3.6 16 5.5 0.1 2.9 2 1 0 2 2 2 0 Dynamin family S8_pro-domain PF16470.5 ORY41881.1 - 0.082 13.7 0.1 0.69 10.7 0.0 2.2 2 0 0 2 2 2 0 Peptidase S8 pro-domain BTB PF00651.31 ORY41882.1 - 6.7e-08 32.7 0.8 5.3e-07 29.9 0.1 2.3 2 0 0 2 2 2 1 BTB/POZ domain cNMP_binding PF00027.29 ORY41884.1 - 4.3e-15 55.6 0.0 1.2e-14 54.1 0.0 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Tmemb_170 PF10190.9 ORY41884.1 - 0.059 13.7 2.0 0.081 13.3 0.1 2.1 2 0 0 2 2 2 0 Putative transmembrane protein 170 NAM-associated PF14303.6 ORY41886.1 - 8.3e-15 55.9 3.5 1.1e-14 55.5 3.5 1.2 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain MSA-2c PF12238.8 ORY41886.1 - 0.017 15.1 3.0 0.017 15.1 3.0 1.6 1 1 0 1 1 1 0 Merozoite surface antigen 2c DUF4529 PF15032.6 ORY41887.1 - 0.1 11.7 0.1 0.2 10.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4529) VWA_2 PF13519.6 ORY41888.1 - 5.1e-08 33.5 0.0 5.8e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 von Willebrand factor type A domain USP7_ICP0_bdg PF12436.8 ORY41889.1 - 2.1e-56 190.9 0.7 1.2e-53 181.9 0.1 2.3 2 0 0 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 ORY41889.1 - 8e-56 189.0 0.5 1e-53 182.1 0.0 3.2 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 ORY41889.1 - 4.2e-50 170.6 0.3 8.1e-50 169.7 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY41889.1 - 6.2e-23 81.9 0.0 3.4e-22 79.4 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 ORY41889.1 - 4.4e-05 23.6 0.0 0.00013 22.1 0.0 1.8 1 0 0 1 1 1 1 MATH domain TRAM_LAG1_CLN8 PF03798.16 ORY41890.1 - 0.013 15.2 5.5 0.015 15.0 5.2 1.3 1 1 0 1 1 1 0 TLC domain HAD_2 PF13419.6 ORY41891.1 - 4.6e-19 69.2 0.0 6.3e-19 68.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY41891.1 - 1.2e-11 45.3 0.1 1.7e-09 38.3 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ORY41891.1 - 0.00066 19.7 0.0 2.2 8.5 0.0 2.6 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY41891.1 - 0.0026 18.2 0.1 0.015 15.7 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY41891.1 - 0.035 14.2 0.0 0.062 13.4 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Lar_N PF09861.9 ORY41891.1 - 0.18 10.9 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Lactate racemase N-terminal domain Ank_2 PF12796.7 ORY41892.1 - 2.3e-32 111.4 0.1 1.8e-11 44.5 0.0 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY41892.1 - 9.2e-15 54.5 1.7 0.0012 19.1 0.1 6.4 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY41892.1 - 7.3e-13 48.8 0.1 0.021 15.4 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY41892.1 - 2e-09 37.5 2.0 0.018 15.4 0.0 6.4 5 1 1 6 6 6 2 Ankyrin repeat Ank_3 PF13606.6 ORY41892.1 - 2.8e-09 36.4 0.1 4 8.3 0.0 6.5 6 0 0 6 6 6 3 Ankyrin repeat Ank_2 PF12796.7 ORY41893.1 - 1.2e-11 45.0 0.0 0.00016 22.2 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY41893.1 - 3.7e-08 33.8 0.0 0.0047 17.5 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY41893.1 - 1.5e-07 31.2 0.0 0.0039 17.6 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ORY41893.1 - 3.3e-05 24.1 0.0 0.026 14.8 0.0 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY41893.1 - 0.0024 18.2 0.0 0.79 10.3 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeat Sel1 PF08238.12 ORY41894.1 - 1.7e-16 60.3 1.9 2.2e-07 31.3 0.1 2.3 2 0 0 2 2 2 2 Sel1 repeat TPR_17 PF13431.6 ORY41894.1 - 0.00016 21.8 0.4 3.7 8.1 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY41894.1 - 0.021 15.4 0.5 3.6 8.3 0.2 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY41894.1 - 0.089 12.9 0.2 8.9 6.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY41894.1 - 0.11 13.2 1.1 0.35 11.6 0.1 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat Macoilin PF09726.9 ORY41897.1 - 3.2 6.2 4.9 3.8 5.9 4.9 1.1 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 ORY41897.1 - 4.3 6.4 19.6 5.4 6.1 19.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein RhoGAP PF00620.27 ORY41898.1 - 6.5e-10 39.0 0.7 1.5e-09 37.8 0.7 1.6 1 0 0 1 1 1 1 RhoGAP domain Syja_N PF02383.18 ORY41899.1 - 1.4e-64 218.5 0.0 2.1e-64 217.9 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Ank_2 PF12796.7 ORY41900.1 - 7.2e-44 148.3 1.1 1.8e-09 38.1 0.0 4.1 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY41900.1 - 1.2e-16 60.8 1.1 0.0011 19.5 0.0 6.1 2 2 6 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY41900.1 - 2.3e-16 58.2 1.0 0.16 12.6 0.1 7.4 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.6 ORY41900.1 - 1.7e-15 56.9 6.9 0.023 15.0 0.1 8.1 2 2 6 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.30 ORY41900.1 - 1.9e-12 47.1 3.4 0.12 12.9 0.1 7.8 7 1 1 8 8 8 4 Ankyrin repeat ADH_zinc_N_2 PF13602.6 ORY41900.1 - 0.012 16.7 0.3 1.6 9.8 0.3 2.3 1 1 0 1 1 1 0 Zinc-binding dehydrogenase F-box PF00646.33 ORY41900.1 - 0.13 12.2 0.2 0.32 10.9 0.2 1.7 1 0 0 1 1 1 0 F-box domain Glyco_hydro_9 PF00759.19 ORY41901.1 - 1.9e-26 93.5 3.7 2.5e-26 93.1 3.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 CelD_N PF02927.14 ORY41901.1 - 1.1e-09 39.1 0.5 4.1e-09 37.2 0.0 2.3 2 0 0 2 2 2 1 Cellulase N-terminal ig-like domain FtsH_ext PF06480.15 ORY41901.1 - 0.44 10.9 2.3 3.3 8.1 2.3 2.3 1 1 0 1 1 1 0 FtsH Extracellular MPDZ_u10 PF16667.5 ORY41902.1 - 0.04 14.8 0.5 0.099 13.6 0.5 1.7 1 0 0 1 1 1 0 Unstructured region 10 on multiple PDZ protein SH3_19 PF18597.1 ORY41902.1 - 0.12 12.3 0.2 0.45 10.4 0.1 2.1 2 0 0 2 2 2 0 Myosin X N-terminal SH3 domain Zn_clus PF00172.18 ORY41903.1 - 0.0082 16.3 1.0 0.029 14.5 1.0 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 ORY41904.1 - 1e-08 35.2 5.5 1.7e-08 34.4 5.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 ORY41905.1 - 0.025 14.7 0.9 0.041 14.0 0.9 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.7 ORY41906.1 - 6.6e-24 84.3 0.9 3.2e-10 40.4 0.0 3.8 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY41906.1 - 2.7e-11 43.8 2.9 1.9e-05 25.1 0.0 5.7 2 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY41906.1 - 6e-08 32.8 4.2 0.42 11.0 0.1 5.9 5 2 1 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY41906.1 - 1.1e-06 28.5 3.1 11 7.0 0.0 6.8 8 0 0 8 8 8 2 Ankyrin repeat Ank PF00023.30 ORY41906.1 - 3.6e-06 27.2 4.0 1.1 9.9 0.0 6.0 3 2 2 5 5 5 2 Ankyrin repeat Mito_carr PF00153.27 ORY41907.1 - 1.3e-27 95.6 0.2 2.1e-19 69.2 0.0 2.0 1 1 1 2 2 2 2 Mitochondrial carrier protein Voltage_CLC PF00654.20 ORY41907.1 - 0.0075 15.6 0.3 0.011 15.1 0.3 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel Aldo_ket_red PF00248.21 ORY41909.1 - 4.2e-86 288.8 0.0 4.7e-86 288.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Nitro_FeMo-Co PF02579.17 ORY41909.1 - 0.13 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor HDC PF02329.16 ORY41909.1 - 0.19 10.8 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Histidine carboxylase PI chain ABC_tran PF00005.27 ORY41910.1 - 7.7e-49 165.7 1.3 4.5e-32 111.4 0.1 3.4 2 1 1 3 3 3 3 ABC transporter ABC_membrane PF00664.23 ORY41910.1 - 3e-29 102.5 29.8 8.6e-16 58.4 10.7 3.8 2 2 1 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 ORY41910.1 - 6.9e-07 28.9 8.1 0.56 9.6 0.0 4.4 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY41910.1 - 3.6e-05 23.4 1.4 0.11 12.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 ORY41910.1 - 3.6e-05 23.7 7.6 0.082 12.7 0.2 4.3 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 ORY41910.1 - 0.00094 19.3 2.1 0.019 15.1 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY41910.1 - 0.019 15.3 0.2 8.7 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 ORY41910.1 - 0.02 15.2 3.3 6.7 7.0 0.2 3.2 2 1 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 ORY41910.1 - 0.021 14.8 3.0 0.54 10.1 0.1 2.9 3 0 0 3 3 3 0 RsgA GTPase AAA_23 PF13476.6 ORY41910.1 - 0.034 14.6 5.3 0.56 10.7 0.6 2.4 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 ORY41910.1 - 0.1 12.3 0.8 0.39 10.4 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 ORY41910.1 - 0.15 12.2 1.1 3.1 8.0 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 ORY41910.1 - 1.6 8.8 3.4 1.7 8.7 0.3 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain Ninjurin PF04923.12 ORY41911.1 - 0.1 12.5 0.3 0.1 12.5 0.3 2.1 2 1 0 2 2 2 0 Ninjurin F-box-like PF12937.7 ORY41913.1 - 0.0036 17.2 0.0 0.0079 16.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY41913.1 - 0.004 17.0 0.2 0.0082 16.0 0.2 1.5 1 0 0 1 1 1 1 F-box domain RUN PF02759.19 ORY41914.1 - 8e-05 22.6 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 RUN domain Peptidase_S10 PF00450.22 ORY41916.1 - 4.9e-77 260.1 5.1 8.7e-43 147.3 0.1 2.0 1 1 1 2 2 2 2 Serine carboxypeptidase FAD_binding_3 PF01494.19 ORY41917.1 - 2.1e-09 37.1 0.0 8.3e-06 25.3 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 ORY41917.1 - 0.00084 18.3 0.1 0.0012 17.7 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 ORY41917.1 - 0.009 15.3 0.2 0.015 14.6 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY41917.1 - 0.011 15.0 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GRAM PF02893.20 ORY41918.1 - 1.2e-22 79.9 0.0 2.1e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 GRAM domain VASt PF16016.5 ORY41918.1 - 1.1e-21 77.8 3.1 3.2e-21 76.3 0.0 2.4 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain Vps36_ESCRT-II PF11605.8 ORY41918.1 - 0.0012 19.0 0.0 0.0043 17.2 0.0 1.9 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.18 ORY41919.1 - 4.5e-07 29.1 2.3 8.8e-07 28.1 2.3 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Asparaginase_2 PF01112.18 ORY41921.1 - 5.3e-20 71.7 0.3 3e-15 56.0 0.0 2.0 2 0 0 2 2 2 2 Asparaginase Myc_N PF01056.18 ORY41922.1 - 0.00098 19.1 1.3 0.0012 18.9 1.3 1.1 1 0 0 1 1 1 1 Myc amino-terminal region TRAP_alpha PF03896.16 ORY41922.1 - 0.051 12.8 2.2 0.055 12.7 2.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Vfa1 PF08432.10 ORY41922.1 - 0.19 12.1 6.5 0.21 11.9 6.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAM176 PF14851.6 ORY41922.1 - 0.62 9.7 5.0 0.73 9.5 5.0 1.3 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 ORY41922.1 - 4.5 5.2 13.0 5.1 5.1 13.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 ORY41922.1 - 5 5.3 11.1 5.4 5.2 11.1 1.0 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.12 ORY41922.1 - 5.6 6.2 12.5 7.4 5.8 12.5 1.1 1 0 0 1 1 1 0 NOA36 protein Ank_2 PF12796.7 ORY41923.1 - 2.3e-33 114.6 3.4 3.7e-08 33.8 0.0 5.0 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY41923.1 - 4.1e-23 79.0 4.5 0.023 15.2 0.0 8.4 8 1 1 9 9 9 6 Ankyrin repeat Ank_4 PF13637.6 ORY41923.1 - 1.8e-18 66.6 3.1 0.00028 21.4 0.0 4.9 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY41923.1 - 1.7e-11 44.1 9.1 0.04 14.2 0.0 6.9 3 2 5 8 8 8 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY41923.1 - 2.3e-10 40.4 7.4 0.12 12.9 0.1 7.1 3 3 3 6 6 6 3 Ankyrin repeat Shigella_OspC PF06128.11 ORY41923.1 - 0.032 14.0 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Shigella flexneri OspC protein VWA_3_C PF18571.1 ORY41923.1 - 0.14 12.0 0.0 3.2 7.7 0.0 2.5 2 0 0 2 2 2 0 von Willebrand factor type A C-terminal domain TLP-20 PF06088.11 ORY41924.1 - 1.8 8.4 9.5 3.8 7.4 0.0 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) G-alpha PF00503.20 ORY41926.1 - 3.9e-89 299.3 6.7 2.2e-88 296.8 6.7 1.8 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY41926.1 - 2.2e-12 46.8 0.5 6.1e-08 32.3 0.2 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY41926.1 - 0.0065 16.5 0.0 0.83 9.8 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORY41926.1 - 0.0066 15.8 0.6 0.11 11.8 0.1 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Roc PF08477.13 ORY41926.1 - 0.01 16.0 0.1 5.4 7.3 0.0 2.6 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 ORY41926.1 - 0.02 14.4 0.1 7.1 6.1 0.0 2.8 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Peptidase_M1 PF01433.20 ORY41927.1 - 4.7e-70 235.5 2.9 7.2e-70 234.9 2.9 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 ORY41927.1 - 2.7e-43 148.7 0.5 3.2e-42 145.2 0.5 2.3 1 1 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 ORY41927.1 - 1.2e-39 136.5 0.0 1.9e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Piwi PF02171.17 ORY41928.1 - 2.6e-86 289.6 0.0 4.1e-86 288.9 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 ORY41928.1 - 6.1e-18 65.8 0.0 1.8e-17 64.3 0.1 1.8 2 0 0 2 2 2 1 N-terminal domain of argonaute PAZ PF02170.22 ORY41928.1 - 3.5e-10 39.8 0.0 6.2e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 ORY41928.1 - 2.6e-09 36.6 0.1 5.9e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 ORY41928.1 - 2.8e-08 33.9 0.0 7.1e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 ORY41928.1 - 1.2e-06 28.8 0.0 2.7e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain PQQ_2 PF13360.6 ORY41929.1 - 0.00018 21.2 0.2 0.00059 19.5 0.2 1.9 2 1 0 2 2 2 1 PQQ-like domain Ras PF00071.22 ORY41930.1 - 1.8e-52 177.2 0.0 2e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY41930.1 - 2.6e-19 69.6 0.0 3.5e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY41930.1 - 2.5e-06 27.0 0.0 3.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY41930.1 - 0.0079 15.7 0.0 0.039 13.5 0.0 1.8 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FKBP_C PF00254.28 ORY41931.1 - 9.9e-30 102.7 0.0 1.3e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CaM-KIIN PF15170.6 ORY41931.1 - 0.074 13.2 0.0 0.21 11.8 0.0 1.7 1 1 1 2 2 2 0 Calcium/calmodulin-dependent protein kinase II inhibitor FKBP_C PF00254.28 ORY41932.1 - 1.6e-31 108.5 0.0 2.9e-31 107.6 0.0 1.4 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4294 PF14127.6 ORY41933.1 - 0.18 11.7 0.0 0.44 10.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) UCH PF00443.29 ORY41936.1 - 6.4e-71 238.9 0.0 1.3e-70 237.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY41936.1 - 3.2e-17 63.1 0.0 4.8e-09 36.3 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 ORY41936.1 - 6.1e-06 26.1 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal RSF PF14876.6 ORY41936.1 - 0.094 11.7 0.0 0.59 9.0 0.0 1.9 2 0 0 2 2 2 0 Respiratory growth transcriptional regulator MFS_1 PF07690.16 ORY41937.1 - 1.1e-40 139.7 45.3 1.1e-40 139.7 45.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY41937.1 - 2e-10 40.2 11.3 2e-10 40.2 11.3 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 ORY41937.1 - 1.2e-08 33.9 16.1 1.2e-08 33.9 16.1 2.2 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 ORY41937.1 - 0.0022 16.6 12.4 0.0022 16.6 12.4 3.4 2 1 3 5 5 5 2 MFS/sugar transport protein RVT_thumb PF06817.14 ORY41937.1 - 0.082 12.8 0.2 0.38 10.6 0.0 2.1 2 0 0 2 2 2 0 Reverse transcriptase thumb domain COX6B PF02297.17 ORY41939.1 - 1.3e-12 47.8 0.8 5.4e-12 45.8 0.8 1.8 1 1 0 1 1 1 1 Cytochrome oxidase c subunit VIb Chal_sti_synt_C PF02797.15 ORY41939.1 - 0.027 14.5 0.0 0.035 14.1 0.0 1.1 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain Phosphoesterase PF04185.14 ORY41940.1 - 7.9e-57 193.1 0.6 1e-56 192.7 0.6 1.1 1 0 0 1 1 1 1 Phosphoesterase family zf-C2H2 PF00096.26 ORY41941.1 - 1.4e-05 25.3 8.5 0.00029 21.1 0.5 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY41941.1 - 0.00025 21.3 3.1 0.014 15.8 0.1 2.8 2 1 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY41941.1 - 0.00038 21.1 10.3 0.0048 17.6 0.3 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORY41941.1 - 0.0074 16.5 7.9 0.0079 16.4 0.3 2.9 2 1 1 3 3 3 1 Aberrant zinc-finger Carb_anhydrase PF00194.21 ORY41943.1 - 1.1e-25 90.6 0.2 1.1e-23 84.1 0.1 2.3 1 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 ORY41944.1 - 1e-31 110.4 0.0 1.9e-25 89.8 0.0 2.3 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 ORY41945.1 - 1.9e-33 116.1 0.5 6.8e-26 91.3 0.4 2.3 1 1 1 2 2 2 2 Eukaryotic-type carbonic anhydrase FAD-oxidase_C PF02913.19 ORY41946.1 - 5.7e-59 199.8 0.1 7.6e-59 199.3 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ORY41946.1 - 4.2e-38 130.2 0.0 7.9e-38 129.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_31 PF01055.26 ORY41949.1 - 3.7e-146 487.8 2.3 4.5e-146 487.5 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 ORY41949.1 - 6.9e-10 39.1 0.2 2.8e-08 33.9 0.0 3.2 2 1 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 ORY41949.1 - 2.2e-06 27.8 0.0 4.7e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) DUF3905 PF13045.6 ORY41949.1 - 0.085 12.9 0.2 1.7 8.7 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3905) Ank_2 PF12796.7 ORY41950.1 - 1.3e-35 121.8 16.0 1e-07 32.5 0.1 7.5 2 2 6 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY41950.1 - 6.3e-28 96.8 30.2 0.00031 21.2 0.1 10.0 8 2 2 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY41950.1 - 3.4e-21 75.0 23.7 0.084 13.2 0.1 12.3 5 4 8 13 13 13 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY41950.1 - 2.6e-17 61.1 15.5 2.9 8.7 0.0 13.5 15 1 1 16 16 16 5 Ankyrin repeat Ank PF00023.30 ORY41950.1 - 0.0048 17.3 13.8 35 5.1 0.0 9.0 6 2 2 8 8 8 0 Ankyrin repeat DUF1979 PF09322.10 ORY41950.1 - 0.069 13.1 0.1 86 3.2 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1979) TctA PF01970.16 ORY41951.1 - 0.0047 15.7 0.5 0.062 12.0 0.5 2.1 2 0 0 2 2 2 2 Tripartite tricarboxylate transporter TctA family Spore_YabQ PF09578.10 ORY41951.1 - 0.045 14.0 3.0 4 7.7 0.0 2.4 2 0 0 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) RINGv PF12906.7 ORY41953.1 - 8.7e-06 25.8 4.3 1.5e-05 25.1 4.3 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 ORY41953.1 - 0.0066 16.8 2.2 0.014 15.7 2.2 1.6 1 0 0 1 1 1 1 Ring finger domain Peptidase_S10 PF00450.22 ORY41955.1 - 4.9e-85 286.5 0.4 5.7e-85 286.2 0.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Cutinase PF01083.22 ORY41956.1 - 0.00082 19.4 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Cutinase F-box-like PF12937.7 ORY41956.1 - 0.033 14.1 1.2 0.88 9.5 0.2 2.6 2 0 0 2 2 2 0 F-box-like LRR_4 PF12799.7 ORY41956.1 - 0.045 14.2 1.0 3 8.4 0.4 3.4 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) RhoGEF PF00621.20 ORY41957.1 - 2.1e-40 138.9 3.2 8.9e-40 136.9 1.8 2.1 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.18 ORY41957.1 - 5.1e-18 65.6 0.3 2.1e-17 63.6 0.0 2.1 2 0 0 2 2 2 1 BAR domain SH3_9 PF14604.6 ORY41957.1 - 1.3e-08 34.5 0.4 2.6e-08 33.6 0.4 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY41957.1 - 2.1e-07 30.5 0.1 6.1e-07 29.0 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY41957.1 - 4e-07 29.5 3.3 1.5e-06 27.7 3.3 2.0 1 1 0 1 1 1 1 SH3 domain cNMP_binding PF00027.29 ORY41958.1 - 9e-15 54.5 0.0 2.3e-14 53.2 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 ORY41958.1 - 1.4e-06 27.7 17.4 2.4e-06 27.0 17.4 1.3 1 0 0 1 1 1 1 Ion transport protein Tmemb_170 PF10190.9 ORY41958.1 - 0.021 15.2 0.4 0.062 13.7 0.4 1.8 1 0 0 1 1 1 0 Putative transmembrane protein 170 cNMP_binding PF00027.29 ORY41959.1 - 4e-15 55.6 0.0 1.2e-14 54.1 0.0 1.9 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Tmemb_170 PF10190.9 ORY41959.1 - 0.12 12.8 0.2 0.12 12.8 0.2 2.2 3 0 0 3 3 3 0 Putative transmembrane protein 170 OKR_DC_1_N PF03709.15 ORY41959.1 - 0.13 12.6 0.1 0.76 10.1 0.1 2.2 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, N-terminal domain OpuAC PF04069.12 ORY41961.1 - 5.4e-18 65.5 0.5 5.9e-10 39.2 0.1 2.1 2 0 0 2 2 2 2 Substrate binding domain of ABC-type glycine betaine transport system Ephrin_rec_like PF07699.13 ORY41961.1 - 0.00046 19.9 6.5 0.00046 19.9 6.5 2.5 2 0 0 2 2 2 1 Putative ephrin-receptor like NCD3G PF07562.14 ORY41961.1 - 0.00051 20.0 4.5 0.001 19.0 4.5 1.6 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 ORY41961.1 - 4.1 7.9 8.0 1.1 9.7 2.3 2.5 2 0 0 2 2 2 0 TNFR/NGFR cysteine-rich region DRMBL PF07522.14 ORY41962.1 - 2.2e-28 98.6 0.0 3.4e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 ORY41962.1 - 0.0021 17.6 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY41962.1 - 0.019 15.0 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Lipase_3 PF01764.25 ORY41963.1 - 3.2e-12 46.5 0.0 6.2e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORY41963.1 - 0.12 12.9 1.9 0.33 11.5 0.3 2.3 1 1 0 2 2 2 0 Alpha/beta hydrolase family ArnB_C PF18677.1 ORY41964.1 - 0.21 11.7 4.3 0.48 10.6 4.3 1.5 1 0 0 1 1 1 0 Archaellum regulatory network B, C-terminal domain Methyltransf_25 PF13649.6 ORY41965.1 - 1e-07 32.5 0.0 2.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY41965.1 - 5.7e-06 26.3 0.0 9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY41965.1 - 1.9e-05 25.3 0.0 5.3e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY41965.1 - 2.8e-05 24.7 0.0 5.8e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY41965.1 - 0.00012 21.9 0.0 0.00024 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 ORY41965.1 - 0.052 13.5 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MOZART1 PF12554.8 ORY41965.1 - 0.054 13.3 0.1 14 5.6 0.0 2.5 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated MTS PF05175.14 ORY41965.1 - 0.077 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain WLM PF08325.10 ORY41966.1 - 2.7e-38 132.0 0.0 3.9e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 ORY41966.1 - 1.7e-07 30.5 14.6 0.00028 20.1 1.6 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DZR PF12773.7 ORY41966.1 - 0.016 15.2 3.3 0.037 14.0 3.4 1.6 1 1 0 1 1 1 0 Double zinc ribbon DUF5567 PF17722.1 ORY41966.1 - 0.024 14.5 0.0 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5567) C1_2 PF03107.16 ORY41966.1 - 0.27 11.6 3.9 7.3 7.0 0.3 2.6 2 0 0 2 2 2 0 C1 domain zf-CHY PF05495.12 ORY41966.1 - 0.57 10.7 3.4 6.6 7.3 3.4 2.3 1 1 0 1 1 1 0 CHY zinc finger zf-C4pol PF14260.6 ORY41966.1 - 1 9.9 4.9 24 5.5 6.0 2.2 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta MFS_1 PF07690.16 ORY41967.1 - 9.4e-36 123.4 47.4 3.1e-35 121.7 47.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY41967.1 - 4.2e-13 49.0 13.5 4.2e-13 49.0 13.5 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 ORY41967.1 - 2.2e-11 42.9 19.5 2.9e-11 42.5 19.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1133 PF06576.11 ORY41970.1 - 0.058 12.8 0.1 0.11 11.9 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1133) MFS_1 PF07690.16 ORY41971.1 - 1.3e-43 149.3 60.2 2e-41 142.1 60.2 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY41971.1 - 8.9e-15 54.5 11.3 8.9e-15 54.5 11.3 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 ORY41971.1 - 4.7e-12 45.1 24.7 5.8e-12 44.8 24.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ASFV_L11L PF05293.11 ORY41971.1 - 1.9 8.8 5.1 6.1 7.3 0.8 2.6 1 1 1 2 2 2 0 African swine fever virus (ASFV) L11L protein 7TMR-DISM_7TM PF07695.11 ORY41971.1 - 8.9 6.1 37.4 0.027 14.4 20.6 3.0 2 2 0 2 2 2 0 7TM diverse intracellular signalling KfrA_N PF11740.8 ORY41973.1 - 0.57 10.9 5.0 1 10.0 3.5 2.2 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term CxC4 PF18717.1 ORY41974.1 - 6.3e-35 119.9 1.0 6.3e-35 119.9 1.0 2.0 2 0 0 2 2 2 1 CxC4 like cysteine cluster associated with KDZ transposases MFS_1 PF07690.16 ORY41975.1 - 1.6e-37 129.3 49.6 2.9e-37 128.4 49.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY41975.1 - 6.6e-14 51.2 27.7 8.7e-14 50.9 27.7 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY41975.1 - 5e-06 25.6 10.9 5e-06 25.6 10.9 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter Stevor PF17410.2 ORY41975.1 - 2.8 7.4 3.3 0.7 9.4 0.1 1.6 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame MFS_1 PF07690.16 ORY41976.1 - 7.7e-41 140.2 51.8 7.7e-41 140.2 51.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY41976.1 - 2.6e-11 43.1 11.4 2.6e-11 43.1 11.4 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 ORY41976.1 - 2e-10 39.7 27.3 2.8e-10 39.3 27.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ORY41977.1 - 2e-37 129.0 34.8 3e-37 128.4 34.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY41977.1 - 9.5e-13 47.4 11.0 9.5e-13 47.4 11.0 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY41977.1 - 1.4e-11 44.0 10.3 1.4e-11 44.0 10.3 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY41978.1 - 3e-38 131.6 50.7 7.5e-38 130.4 47.2 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY41978.1 - 2.7e-13 49.6 7.3 2.7e-13 49.6 7.3 2.9 1 1 1 3 3 3 1 Sugar (and other) transporter MASE2 PF05230.11 ORY41978.1 - 2.1 8.5 8.6 0.7 10.0 2.6 3.4 3 1 0 3 3 3 0 MASE2 domain Sigma_reg_N PF13800.6 ORY41978.1 - 4.6 7.6 5.4 13 6.2 0.4 3.3 2 1 1 3 3 3 0 Sigma factor regulator N-terminal MFS_1 PF07690.16 ORY41979.1 - 2.2e-42 145.3 46.5 2.2e-42 145.3 46.5 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY41979.1 - 3.9e-07 29.3 13.2 3.9e-07 29.3 13.2 3.3 3 1 0 3 3 3 2 Sugar (and other) transporter DUF4231 PF14015.6 ORY41979.1 - 0.6 10.6 0.1 0.6 10.6 0.1 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF4231) MFS_1 PF07690.16 ORY41980.1 - 6.5e-12 45.0 27.6 1.5e-09 37.3 4.4 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY41980.1 - 0.00031 19.7 0.7 0.00031 19.7 0.7 3.2 3 0 0 3 3 3 2 Sugar (and other) transporter DUF4407 PF14362.6 ORY41980.1 - 0.88 8.9 5.9 1.1 8.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MFS_1 PF07690.16 ORY41981.1 - 1.8e-29 102.8 63.0 2e-29 102.7 58.6 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily 60KD_IMP PF02096.20 ORY41982.1 - 8.9e-29 100.5 5.2 1.1e-28 100.3 5.2 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein CAP_N PF01213.19 ORY41982.1 - 0.066 12.7 0.2 0.1 12.1 0.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Co_AT_N PF12557.8 ORY41982.1 - 6.5 6.8 7.6 0.3 11.0 1.9 1.8 2 0 0 2 2 2 0 Cob(I)alamin adenosyltransferase N terminal Peptidase_M16_C PF05193.21 ORY41983.1 - 2.8e-40 138.3 0.1 2.8e-39 135.0 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ORY41983.1 - 2.6e-34 118.4 0.1 5.1e-34 117.4 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) PAP2 PF01569.21 ORY41986.1 - 2.6e-23 82.3 2.0 2.6e-23 82.3 2.0 1.8 2 1 0 2 2 2 1 PAP2 superfamily Colicin_V PF02674.16 ORY41986.1 - 0.023 14.7 3.3 1.7 8.6 0.2 2.6 2 1 1 3 3 3 0 Colicin V production protein DUF2182 PF09948.9 ORY41986.1 - 0.038 13.9 1.1 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 Predicted metal-binding integral membrane protein (DUF2182) Ank_2 PF12796.7 ORY41988.1 - 5.4e-12 46.1 0.0 6.1e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY41988.1 - 1.7e-10 40.8 0.1 7.8e-05 22.9 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 ORY41988.1 - 5.7e-08 32.4 0.0 0.018 15.5 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 ORY41988.1 - 1.9e-07 31.5 0.8 0.0016 18.9 0.1 2.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY41988.1 - 1.8e-06 28.1 0.0 0.018 15.4 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) VWA_3_C PF18571.1 ORY41988.1 - 0.008 16.0 0.2 5.4 7.0 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A C-terminal domain DUF3447 PF11929.8 ORY41988.1 - 0.23 11.4 0.0 12 6.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) Lipase_3 PF01764.25 ORY41989.1 - 1.9e-11 44.0 0.0 3.6e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORY41989.1 - 0.031 14.9 0.0 0.061 13.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY41989.1 - 0.041 13.1 0.0 0.072 12.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Transmemb_17 PF09799.9 ORY41989.1 - 0.62 10.7 4.7 1.2 9.8 4.3 1.7 1 1 1 2 2 2 0 Predicted membrane protein DUF4793 PF16041.5 ORY41990.1 - 0.0041 17.3 0.0 0.0071 16.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4793) Aldolase PF01081.19 ORY41990.1 - 0.16 11.3 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 KDPG and KHG aldolase Aldo_ket_red PF00248.21 ORY41991.1 - 2.3e-28 99.3 0.0 3e-27 95.6 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 ORY41992.1 - 2.9e-16 59.5 0.0 5.2e-09 35.7 0.0 2.7 1 1 1 3 3 3 2 Aldo/keto reductase family Aldo_ket_red PF00248.21 ORY41993.1 - 1.2e-20 74.0 0.0 7.6e-18 64.7 0.0 3.0 1 1 0 1 1 1 1 Aldo/keto reductase family SPC25 PF06703.11 ORY41994.1 - 0.0017 18.2 0.4 0.0019 18.0 0.4 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF2207 PF09972.9 ORY41994.1 - 0.1 11.3 0.6 0.11 11.3 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Herpes_US9 PF06072.11 ORY41994.1 - 0.72 9.8 5.3 6.7 6.7 4.6 2.5 2 1 0 2 2 2 0 Alphaherpesvirus tegument protein US9 DUF3764 PF12594.8 ORY41995.1 - 0.0072 16.4 0.0 0.056 13.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3764) Inhibitor_I9 PF05922.16 ORY41995.1 - 0.03 15.0 0.0 0.058 14.1 0.0 1.5 1 1 0 1 1 1 0 Peptidase inhibitor I9 LysM PF01476.20 ORY41996.1 - 5.7e-07 29.5 0.1 1.8e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 LysM domain AA_permease_2 PF13520.6 ORY41997.1 - 1e-63 215.7 59.2 1.2e-63 215.4 59.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY41997.1 - 2.9e-19 69.0 49.4 3.8e-19 68.6 49.4 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_M24 PF00557.24 ORY41998.1 - 1.6e-10 41.1 0.0 2.1e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 WD40 PF00400.32 ORY41999.1 - 1.1e-14 54.6 8.9 1.3e-07 32.1 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY41999.1 - 1.3e-08 35.0 1.8 0.0006 20.1 0.2 3.3 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY41999.1 - 0.017 14.1 0.0 0.037 13.0 0.0 1.6 1 1 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4524 PF15025.6 ORY41999.1 - 0.33 10.7 1.9 1.1 9.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4524) IKI3 PF04762.12 ORY41999.1 - 0.59 8.1 2.8 8.2 4.3 0.1 2.5 2 1 0 3 3 3 0 IKI3 family CAF1C_H4-bd PF12265.8 ORY42000.1 - 1.8e-12 47.3 0.0 2.7e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex SDA1 PF05285.12 ORY42000.1 - 4.5 6.6 14.1 5.1 6.4 14.1 1.1 1 0 0 1 1 1 0 SDA1 Spc24 PF08286.11 ORY42002.1 - 2.5e-19 69.5 0.2 3.1e-19 69.2 0.2 1.1 1 0 0 1 1 1 1 Spc24 subunit of Ndc80 PI_PP_I PF18363.1 ORY42003.1 - 0.0087 16.2 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoinositide phosphatase insertion domain DUF3857 PF12969.7 ORY42003.1 - 0.16 12.0 0.0 0.18 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3857) DUF3619 PF12279.8 ORY42006.1 - 0.12 12.7 0.2 0.17 12.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Sulfate_transp PF00916.20 ORY42007.1 - 3.1e-89 299.4 25.4 4.1e-89 299.0 25.4 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORY42007.1 - 3e-11 43.0 0.0 6.9e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ORY42007.1 - 0.004 17.5 17.9 0.21 12.0 4.9 3.1 2 1 0 2 2 2 2 Molybdate transporter of MFS superfamily Na_H_antiport_2 PF13726.6 ORY42007.1 - 0.0044 17.1 0.5 0.0044 17.1 0.5 2.7 3 0 0 3 3 3 1 Na+-H+ antiporter family STAS_2 PF13466.6 ORY42007.1 - 0.037 14.4 0.0 0.078 13.3 0.0 1.5 1 0 0 1 1 1 0 STAS domain HRG PF16954.5 ORY42008.1 - 0.16 12.4 2.8 0.89 10.0 0.1 3.1 2 0 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene DUF2254 PF10011.9 ORY42008.1 - 1.6 7.5 6.1 0.2 10.4 1.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) dCache_1 PF02743.18 ORY42009.1 - 5.1e-07 29.7 1.1 1.3e-06 28.4 0.4 1.9 1 1 1 2 2 2 1 Cache domain HAMP PF00672.25 ORY42009.1 - 0.071 13.5 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 HAMP domain Kelch_6 PF13964.6 ORY42009.1 - 0.079 13.3 0.2 4.4 7.7 0.0 2.9 2 1 0 2 2 2 0 Kelch motif LapA_dom PF06305.11 ORY42009.1 - 0.17 11.7 0.5 0.34 10.7 0.5 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PPR PF01535.20 ORY42010.1 - 7.1e-13 47.9 1.6 0.085 13.1 0.0 6.9 7 0 0 7 7 7 4 PPR repeat PPR_2 PF13041.6 ORY42010.1 - 1.6e-09 37.8 0.8 0.0062 16.7 0.0 5.2 5 1 1 6 6 6 2 PPR repeat family PPR_3 PF13812.6 ORY42010.1 - 1.6e-08 34.5 0.3 0.0002 21.3 0.0 4.6 3 2 2 5 5 5 1 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORY42010.1 - 0.0001 21.9 0.1 1.1 9.0 0.0 3.8 3 0 0 3 3 3 1 PPR repeat ATP13 PF12921.7 ORY42010.1 - 0.00061 19.6 0.0 3.3 7.6 0.0 3.3 1 1 2 3 3 3 2 Mitochondrial ATPase expression PPR_long PF17177.4 ORY42010.1 - 0.01 15.3 0.4 29 4.0 0.0 3.6 3 1 0 3 3 3 0 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 ORY42010.1 - 0.023 15.5 5.7 11 7.2 0.0 5.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY42010.1 - 0.041 14.5 0.1 3.1 8.5 0.0 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat SPC25 PF06703.11 ORY42011.1 - 0.017 14.9 0.2 0.021 14.6 0.2 1.1 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Herpes_US9 PF06072.11 ORY42011.1 - 0.88 9.5 4.6 6.6 6.7 4.0 2.4 2 1 0 2 2 2 0 Alphaherpesvirus tegument protein US9 DUF2721 PF11026.8 ORY42012.1 - 0.043 13.7 0.2 0.061 13.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) YwcE PF17368.2 ORY42012.1 - 0.072 13.8 0.9 0.11 13.2 0.9 1.2 1 0 0 1 1 1 0 Spore morphogenesis and germination YwcE DUF1676 PF07898.13 ORY42012.1 - 0.073 13.1 0.3 0.1 12.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) Med9 PF07544.13 ORY42012.1 - 0.16 12.1 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Yip1 PF04893.17 ORY42013.1 - 0.024 14.3 0.2 0.026 14.2 0.2 1.1 1 0 0 1 1 1 0 Yip1 domain ADH_zinc_N_2 PF13602.6 ORY42014.1 - 3.8e-15 57.1 0.0 9.8e-15 55.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY42014.1 - 5.8e-12 45.7 0.0 1.2e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY42014.1 - 1.9e-07 30.9 0.0 3.2e-06 27.0 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF3842 PF12953.7 ORY42014.1 - 0.0022 18.4 0.0 0.0043 17.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3842) DapB_N PF01113.20 ORY42014.1 - 0.043 13.9 0.1 0.18 11.9 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.16 ORY42014.1 - 0.062 14.0 0.0 0.12 13.1 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Peptidase_M20 PF01546.28 ORY42015.1 - 3.1e-34 118.5 0.0 3.9e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY42015.1 - 7.8e-11 41.9 0.0 1.9e-10 40.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ORY42015.1 - 0.14 11.8 0.0 0.34 10.6 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M28 LRR_8 PF13855.6 ORY42016.1 - 7.8e-27 92.8 34.5 1.2e-08 34.6 1.2 4.9 4 1 1 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 ORY42016.1 - 5.1e-24 83.9 27.1 3.8e-05 24.0 0.9 6.6 6 0 0 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY42016.1 - 7.2e-11 41.1 36.5 2.3 9.1 0.2 11.8 11 1 1 12 12 12 5 Leucine Rich Repeat LRR_6 PF13516.6 ORY42016.1 - 4.9e-10 38.7 31.0 0.73 10.0 0.3 11.1 11 0 0 11 11 11 5 Leucine Rich repeat F-box PF00646.33 ORY42016.1 - 0.00055 19.7 0.5 0.0018 18.1 0.5 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY42016.1 - 0.11 12.4 0.2 0.3 11.0 0.2 1.7 1 0 0 1 1 1 0 F-box-like Pkinase PF00069.25 ORY42017.1 - 2.1e-32 112.5 0.0 2.3e-31 109.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY42017.1 - 5e-10 39.1 0.0 4.1e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 ORY42017.1 - 1.4e-07 31.7 0.1 0.0034 17.3 0.1 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY42017.1 - 0.032 13.5 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 ORY42017.1 - 0.11 12.0 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase SPX PF03105.19 ORY42017.1 - 0.86 9.5 9.2 1.4 8.7 9.2 1.3 1 0 0 1 1 1 0 SPX domain Glyco_transf_17 PF04724.13 ORY42018.1 - 1.4e-40 139.5 0.2 4.3e-40 137.8 0.2 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 17 PAXIP1_C PF15364.6 ORY42019.1 - 0.17 12.2 0.5 0.34 11.2 0.5 1.4 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein PQQ_3 PF13570.6 ORY42020.1 - 4.5e-05 23.8 0.0 0.93 10.1 0.0 3.1 3 0 0 3 3 3 2 PQQ-like domain WD40 PF00400.32 ORY42020.1 - 6e-05 23.7 0.7 0.0059 17.4 0.0 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF836 PF05768.14 ORY42020.1 - 0.013 15.9 0.8 0.036 14.5 0.8 1.7 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) HalX PF08663.10 ORY42020.1 - 0.02 15.2 1.1 0.02 15.2 1.1 2.2 2 0 0 2 2 2 0 HalX domain FAM76 PF16046.5 ORY42020.1 - 0.12 11.7 4.2 0.15 11.4 4.2 1.2 1 0 0 1 1 1 0 FAM76 protein HDAC4_Gln PF12203.8 ORY42020.1 - 1.1 9.5 8.8 2.2 8.5 8.8 1.5 1 1 0 1 1 1 0 Glutamine rich N terminal domain of histone deacetylase 4 MCM_bind PF09739.9 ORY42022.1 - 1.1e-67 228.8 0.2 1.6e-52 178.8 0.2 2.9 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor ANF_receptor PF01094.28 ORY42023.1 - 2.3e-05 23.7 0.0 3.2e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 ORY42023.1 - 0.00012 21.9 11.9 0.00026 20.8 11.6 1.8 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Ceramidase PF05875.12 ORY42024.1 - 4.4e-15 55.8 0.5 4.9e-15 55.7 0.5 1.0 1 0 0 1 1 1 1 Ceramidase Ceramidase PF05875.12 ORY42025.1 - 1.3e-30 106.7 6.8 1.5e-30 106.5 6.8 1.0 1 0 0 1 1 1 1 Ceramidase DUF3488 PF11992.8 ORY42025.1 - 0.0097 14.9 3.1 0.0097 14.9 3.1 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF3488) DUF4131 PF13567.6 ORY42025.1 - 2.2 7.9 7.2 4.8 6.8 0.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Ycf66_N PF07444.11 ORY42025.1 - 3.7 7.7 6.7 1.1 9.5 0.9 2.7 2 1 1 3 3 3 0 Ycf66 protein N-terminus Ceramidase PF05875.12 ORY42026.1 - 2.5e-59 200.9 12.5 2.9e-59 200.6 12.5 1.0 1 0 0 1 1 1 1 Ceramidase GATA PF00320.27 ORY42027.1 - 1.3e-14 53.5 5.6 2.1e-14 52.8 5.6 1.3 1 0 0 1 1 1 1 GATA zinc finger ADD_DNMT3 PF17980.1 ORY42027.1 - 0.054 13.5 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 Zn_clus PF00172.18 ORY42029.1 - 1.4e-10 41.1 46.2 0.004 17.2 5.4 4.5 4 0 0 4 4 4 4 Fungal Zn(2)-Cys(6) binuclear cluster domain SGL PF08450.12 ORY42030.1 - 2.8e-17 63.1 0.0 3.4e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 ORY42030.1 - 0.00097 19.2 0.0 0.21 11.8 0.0 2.5 2 0 0 2 2 2 1 Strictosidine synthase DUF2371 PF10177.9 ORY42030.1 - 0.02 15.0 0.1 0.031 14.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Pilin_N PF07790.11 ORY42030.1 - 0.022 15.7 2.5 0.058 14.3 2.5 1.7 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal Arylesterase PF01731.20 ORY42030.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Arylesterase Tad PF13400.6 ORY42030.1 - 0.61 10.4 4.7 2.1 8.7 4.7 1.9 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Glyco_transf_90 PF05686.12 ORY42031.1 - 6.6e-27 94.4 0.0 1.4e-26 93.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 90 HTH_45 PF14947.6 ORY42031.1 - 0.099 12.6 0.0 21 5.2 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix SGL PF08450.12 ORY42032.1 - 4.4e-29 101.8 0.2 6e-18 65.3 0.0 3.6 3 1 1 4 4 4 2 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 ORY42032.1 - 2.4e-05 24.4 0.0 0.4 10.9 0.0 2.6 2 0 0 2 2 2 2 Arylesterase PD40 PF07676.12 ORY42032.1 - 0.0037 17.2 0.0 0.61 10.1 0.0 2.8 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat WD40_3 PF15911.5 ORY42032.1 - 0.16 12.0 0.0 0.94 9.5 0.0 2.2 2 0 0 2 2 2 0 WD domain, G-beta repeat Pkinase PF00069.25 ORY42033.1 - 3.7e-54 183.8 0.0 5.2e-54 183.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY42033.1 - 6e-23 81.5 0.0 1.3e-22 80.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY42033.1 - 0.0077 15.6 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY42033.1 - 0.0081 15.5 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ANF_receptor PF01094.28 ORY42034.1 - 5.2e-27 94.9 0.0 7.6e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY42034.1 - 5.3e-18 65.8 0.1 7e-18 65.4 0.1 1.1 1 0 0 1 1 1 1 Periplasmic binding protein Fe-ADH PF00465.19 ORY42034.1 - 0.011 14.6 0.0 0.022 13.6 0.0 1.5 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase DUF771 PF05595.11 ORY42034.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF771) 7tm_3 PF00003.22 ORY42035.1 - 1.5e-11 44.5 7.9 2.3e-11 43.9 7.9 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR CPP1-like PF11833.8 ORY42035.1 - 0.034 13.8 2.8 0.062 13.0 2.1 1.8 1 1 1 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like ANF_receptor PF01094.28 ORY42036.1 - 0.0012 18.0 0.1 0.0018 17.4 0.1 1.3 1 1 0 1 1 1 1 Receptor family ligand binding region Indigoidine_A PF04227.12 ORY42037.1 - 2.4e-113 378.3 2.1 3.5e-113 377.8 2.1 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 ORY42037.1 - 1.1e-22 80.7 4.9 3.2e-20 72.6 3.4 3.4 2 1 0 2 2 2 1 pfkB family carbohydrate kinase NIR_SIR PF01077.22 ORY42037.1 - 0.031 13.8 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain HTH_AraC PF00165.23 ORY42037.1 - 0.19 11.9 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix proteins, AraC family Metallothio_PEC PF02068.16 ORY42039.1 - 0.0009 19.5 52.6 0.046 14.1 25.7 2.1 1 1 1 2 2 2 2 Plant PEC family metallothionein Metallothio_Euk PF12749.7 ORY42039.1 - 0.12 12.6 60.2 1.4e+03 -0.5 60.2 2.3 1 1 0 1 1 1 0 Eukaryotic metallothionein Metallothi_Euk2 PF12809.7 ORY42039.1 - 0.12 12.7 52.8 0.45 10.8 11.2 2.3 1 1 1 2 2 2 0 Eukaryotic metallothionein Metallothio_5 PF02067.15 ORY42039.1 - 1.6 8.9 66.8 28 4.9 27.0 3.9 1 1 1 2 2 2 0 Metallothionein family 5 Lipase_GDSL_2 PF13472.6 ORY42041.1 - 3.9e-21 76.2 0.0 4.5e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY42041.1 - 1.7e-14 54.3 0.0 2.4e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Y_phosphatase3 PF13350.6 ORY42042.1 - 1.8e-37 129.6 0.0 2.3e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 ORY42042.1 - 1.9e-08 34.0 0.1 1.1e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 ORY42042.1 - 9.1e-05 22.1 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 ORY42042.1 - 0.017 14.1 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DSPc PF00782.20 ORY42042.1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Acetyltransf_1 PF00583.25 ORY42043.1 - 1.5e-09 38.1 0.0 2.1e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY42043.1 - 9.6e-09 35.6 0.0 1.4e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY42043.1 - 1e-07 32.1 0.0 1.4e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY42043.1 - 0.00082 19.3 0.0 0.0023 17.9 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY42043.1 - 0.0054 16.7 0.0 0.014 15.4 0.0 1.7 1 1 0 1 1 1 1 FR47-like protein DUF4477 PF14780.6 ORY42044.1 - 2.9e-08 33.6 0.4 4.6e-08 32.9 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) Galactosyl_T PF01762.21 ORY42045.1 - 5.1e-10 39.5 0.3 7.6e-06 25.9 0.2 3.3 2 1 1 3 3 3 3 Galactosyltransferase Fringe PF02434.16 ORY42045.1 - 0.0014 18.1 0.0 0.003 17.0 0.0 1.4 1 0 0 1 1 1 1 Fringe-like KDZ PF18758.1 ORY42046.1 - 1.5e-17 64.0 0.0 3.4e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC2 PF18803.1 ORY42046.1 - 0.044 14.0 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases Galactosyl_T PF01762.21 ORY42049.1 - 6.9e-11 42.3 0.1 4.8e-09 36.3 0.1 2.1 1 1 1 2 2 2 2 Galactosyltransferase Fringe PF02434.16 ORY42049.1 - 0.038 13.4 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Fringe-like RNA_ligase PF09414.10 ORY42052.1 - 2.1e-16 60.7 0.0 6e-16 59.2 0.0 1.8 1 0 0 1 1 1 1 RNA ligase NT5C PF06941.12 ORY42052.1 - 2e-15 57.1 1.3 8.2e-15 55.1 1.3 2.1 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) AAA_33 PF13671.6 ORY42052.1 - 4.9e-13 49.4 0.1 3.8e-06 27.1 0.0 2.4 1 1 1 2 2 2 2 AAA domain DSPc PF00782.20 ORY42052.1 - 1.6e-06 28.0 0.0 1.1e-05 25.2 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain HAD_2 PF13419.6 ORY42052.1 - 4.1e-06 27.0 0.1 1.7e-05 25.0 0.1 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase NIF PF03031.18 ORY42052.1 - 0.00012 21.8 0.0 0.00026 20.8 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Y_phosphatase PF00102.27 ORY42052.1 - 0.0025 17.4 0.0 0.0064 16.1 0.0 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Zeta_toxin PF06414.12 ORY42052.1 - 0.0053 16.0 0.0 0.017 14.4 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin KTI12 PF08433.10 ORY42052.1 - 0.0079 15.7 0.0 0.054 12.9 0.0 2.0 1 1 0 1 1 1 1 Chromatin associated protein KTI12 tRNA_lig_kinase PF08303.11 ORY42052.1 - 0.011 15.8 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 tRNA ligase kinase domain 6PF2K PF01591.18 ORY42052.1 - 0.015 14.6 0.0 0.036 13.4 0.0 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase AAA_22 PF13401.6 ORY42052.1 - 0.081 13.2 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Cytochrom_C1 PF02167.15 ORY42053.1 - 7e-94 313.6 0.0 8.4e-94 313.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 ORY42053.1 - 0.0013 19.0 0.1 0.0038 17.5 0.0 1.9 2 0 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 ORY42053.1 - 0.017 16.3 0.2 0.039 15.1 0.2 1.8 1 1 0 1 1 1 0 Cytochrome c LRR_4 PF12799.7 ORY42054.1 - 0.00026 21.3 8.5 0.42 11.1 0.2 5.9 3 2 5 8 8 8 3 Leucine Rich repeats (2 copies) NnrU PF07298.11 ORY42055.1 - 2.9e-15 56.4 1.2 1.3e-10 41.1 0.4 2.1 1 1 1 2 2 2 2 NnrU protein PEMT PF04191.13 ORY42055.1 - 0.056 13.9 0.4 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 Phospholipid methyltransferase RSN1_7TM PF02714.15 ORY42056.1 - 5.4e-42 144.0 28.0 5.4e-42 144.0 28.0 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 ORY42056.1 - 6.4e-19 68.9 3.5 1.3e-18 67.9 3.5 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PX PF00787.24 ORY42056.1 - 1.2e-17 63.9 0.2 3.6e-17 62.4 0.2 1.9 1 0 0 1 1 1 1 PX domain RSN1_TM PF13967.6 ORY42056.1 - 2.6e-11 43.5 3.1 5.9e-08 32.6 0.0 4.7 5 1 0 5 5 5 2 Late exocytosis, associated with Golgi transport Trypan_PARP PF05887.11 ORY42056.1 - 1.5e-08 34.7 108.6 4.1e-05 23.6 50.8 3.4 2 1 1 3 3 3 2 Procyclic acidic repetitive protein (PARP) FlxA PF14282.6 ORY42056.1 - 0.0078 16.2 1.3 0.023 14.7 1.3 1.7 1 0 0 1 1 1 1 FlxA-like protein DUF919 PF06034.11 ORY42056.1 - 0.22 11.4 5.7 0.55 10.1 5.7 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF2684 PF10885.8 ORY42056.1 - 0.51 10.5 2.5 0.56 10.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2684) SSP160 PF06933.11 ORY42056.1 - 6.3 4.9 13.2 12 3.9 13.2 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Phage_holin_2_4 PF16082.5 ORY42057.1 - 0.011 15.5 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Herpes_pp38 PF04846.13 ORY42057.1 - 0.014 15.3 0.1 0.02 14.8 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein Chordopox_A13L PF05961.11 ORY42057.1 - 0.042 14.1 0.1 0.06 13.6 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus A13L protein MFS_1 PF07690.16 ORY42058.1 - 8.9e-30 103.8 25.1 8.9e-30 103.8 25.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4244 PF14029.6 ORY42058.1 - 0.045 13.2 1.5 0.25 10.8 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) DUF1213 PF06740.12 ORY42060.1 - 0.038 14.6 0.5 0.1 13.2 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1213) ATG13 PF10033.9 ORY42061.1 - 3.5e-37 128.4 0.0 4.7e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 13 RhoGEF67_u2 PF16614.5 ORY42061.1 - 0.0096 16.0 0.1 0.023 14.8 0.1 1.6 1 0 0 1 1 1 1 Unstructured region two on RhoGEF 6 and 7 Prefoldin_2 PF01920.20 ORY42062.1 - 6.6e-24 83.9 7.4 8.3e-24 83.6 7.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit FTA4 PF13093.6 ORY42062.1 - 0.0031 17.4 4.2 0.0038 17.2 4.2 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4709 PF15821.5 ORY42062.1 - 0.0058 16.9 3.6 0.2 11.9 0.2 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4709) DASH_Dam1 PF08653.10 ORY42062.1 - 0.21 11.4 2.8 9.5 6.1 0.1 2.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 GvpL_GvpF PF06386.11 ORY42062.1 - 0.26 11.2 3.5 0.36 10.7 3.4 1.2 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF CHD5 PF04420.14 ORY42062.1 - 0.42 10.4 2.2 1.2 9.0 1.5 1.9 2 0 0 2 2 2 0 CHD5-like protein ZapB PF06005.12 ORY42062.1 - 0.44 11.0 8.6 1.9 9.0 1.3 2.7 3 0 0 3 3 3 0 Cell division protein ZapB DivIC PF04977.15 ORY42062.1 - 0.63 9.9 9.8 3.3 7.5 0.1 2.5 2 1 0 2 2 2 0 Septum formation initiator YabA PF06156.13 ORY42062.1 - 0.7 10.6 5.7 9.7 6.9 0.2 2.2 1 1 1 2 2 2 0 Initiation control protein YabA bZIP_1 PF00170.21 ORY42062.1 - 1.3 9.2 7.1 17 5.6 3.1 2.4 2 0 0 2 2 2 0 bZIP transcription factor TIR_2 PF13676.6 ORY42063.1 - 1.1e-16 61.5 0.0 2.6e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 TIR domain NACHT PF05729.12 ORY42063.1 - 2.4e-06 27.5 0.0 1.2e-05 25.3 0.0 2.5 1 1 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 ORY42063.1 - 0.037 13.8 0.0 0.082 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 ORY42063.1 - 0.096 11.9 0.7 1.7 7.8 0.1 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 ORY42063.1 - 0.12 12.7 0.2 3 8.2 0.0 2.9 2 1 1 3 3 3 0 AAA ATPase domain ANAPC4_WD40 PF12894.7 ORY42064.1 - 0.0044 17.3 0.0 0.021 15.1 0.0 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY42064.1 - 0.014 16.2 0.0 0.034 15.0 0.0 1.7 1 0 0 1 1 1 0 WD domain, G-beta repeat WD40 PF00400.32 ORY42065.1 - 1.6e-38 130.0 18.2 2.7e-06 28.0 0.4 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY42065.1 - 3.7e-20 72.0 2.4 6.1e-05 23.3 0.1 6.0 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY42065.1 - 1.1e-09 37.6 10.9 0.13 10.9 0.1 5.8 1 1 5 6 6 6 5 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORY42065.1 - 1.9e-08 33.7 14.7 0.01 14.8 1.8 5.2 1 1 4 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein CDtoxinA PF03498.14 ORY42065.1 - 2.8e-07 30.2 1.1 0.073 12.7 0.1 3.6 1 1 2 3 3 3 3 Cytolethal distending toxin A/C domain WD40_like PF17005.5 ORY42065.1 - 4.4e-07 29.5 3.4 0.038 13.3 0.4 3.1 2 1 0 3 3 3 3 WD40-like domain Gmad1 PF10647.9 ORY42065.1 - 4.6e-05 23.3 0.7 0.051 13.3 0.0 3.2 1 1 2 3 3 3 2 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.16 ORY42065.1 - 0.069 11.7 0.1 4.2 5.8 0.0 2.5 2 1 1 3 3 3 0 Cytochrome D1 heme domain FLgD_tudor PF13861.6 ORY42065.1 - 2.4 8.5 7.4 0.31 11.3 0.5 3.1 4 1 0 4 4 4 0 FlgD Tudor-like domain DUF3450 PF11932.8 ORY42066.1 - 0.0003 20.2 1.2 0.00034 20.0 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Nsp1_C PF05064.13 ORY42066.1 - 0.00089 19.0 0.9 0.001 18.9 0.9 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region ZapB PF06005.12 ORY42066.1 - 0.0018 18.7 5.0 0.0024 18.3 5.1 1.3 1 1 0 1 1 1 1 Cell division protein ZapB BLOC1_2 PF10046.9 ORY42066.1 - 0.0021 18.3 1.1 0.0027 17.9 1.1 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.6 ORY42066.1 - 0.0023 17.3 1.9 0.0025 17.2 1.9 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding BST2 PF16716.5 ORY42066.1 - 0.0031 18.1 2.0 0.0038 17.8 2.0 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 Spc29 PF17082.5 ORY42066.1 - 0.0034 17.2 0.9 0.0038 17.1 0.9 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 Cluap1 PF10234.9 ORY42066.1 - 0.013 14.9 1.0 0.016 14.6 1.0 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 TMF_DNA_bd PF12329.8 ORY42066.1 - 0.014 15.4 3.0 0.014 15.4 1.5 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.7 ORY42066.1 - 0.02 15.1 2.1 0.028 14.6 2.1 1.4 1 1 0 1 1 1 0 Tropomyosin like APG6_N PF17675.1 ORY42066.1 - 0.027 15.0 1.9 0.032 14.7 1.9 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region YabA PF06156.13 ORY42066.1 - 0.027 15.1 1.1 0.031 14.9 1.1 1.2 1 0 0 1 1 1 0 Initiation control protein YabA Herpes_UL6 PF01763.16 ORY42066.1 - 0.028 13.0 1.5 0.028 12.9 1.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like HlyD_D23 PF16576.5 ORY42066.1 - 0.033 13.4 1.0 0.035 13.3 1.0 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion BSP PF04450.12 ORY42066.1 - 0.034 13.9 0.0 0.06 13.1 0.0 1.3 1 1 0 1 1 1 0 Peptidase of plants and bacteria Rab_bind PF16704.5 ORY42066.1 - 0.036 14.1 0.3 2.8 8.1 0.1 2.3 1 1 1 2 2 2 0 Rab binding domain DUF948 PF06103.11 ORY42066.1 - 0.041 14.1 0.5 0.058 13.7 0.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SlyX PF04102.12 ORY42066.1 - 0.12 13.0 4.7 0.34 11.6 4.7 1.8 1 1 0 1 1 1 0 SlyX Fib_alpha PF08702.10 ORY42066.1 - 0.14 12.3 3.1 0.4 10.9 2.9 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 ORY42066.1 - 0.15 12.3 2.3 0.29 11.4 2.3 1.5 1 0 0 1 1 1 0 Haemolysin XhlA NPV_P10 PF05531.12 ORY42066.1 - 0.26 11.8 2.6 1 9.9 2.7 1.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 ORY42066.1 - 0.8 9.5 5.6 9.6 6.1 0.9 2.0 1 1 1 2 2 2 0 Septum formation initiator MFS_1 PF07690.16 ORY42139.1 - 3e-20 72.5 28.3 3.6e-12 45.9 13.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY42139.1 - 8.5e-08 31.2 5.9 1.7e-07 30.2 5.7 1.5 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.7 ORY42139.1 - 4e-07 29.2 2.7 5.5e-07 28.8 2.7 1.2 1 0 0 1 1 1 1 MFS_1 like family DUF3439 PF11921.8 ORY42140.1 - 1.9 8.5 12.1 4 7.4 12.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SecY PF00344.20 ORY42141.1 - 3.4e-69 233.4 8.6 4.8e-69 232.9 8.6 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 ORY42141.1 - 8e-19 67.2 0.2 8e-19 67.2 0.2 2.5 3 0 0 3 3 3 1 Plug domain of Sec61p SET PF00856.28 ORY42142.1 - 1.4e-11 45.1 0.1 1.3e-10 41.9 0.1 2.4 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 ORY42142.1 - 1.9e-05 24.6 7.6 1.9e-05 24.6 7.6 2.7 2 1 0 2 2 2 1 MYND finger SAF PF08666.12 ORY42142.1 - 0.00021 21.9 0.0 0.29 11.8 0.0 2.4 2 0 0 2 2 2 2 SAF domain zf-Mss51 PF13824.6 ORY42142.1 - 0.028 14.5 6.3 0.076 13.1 6.3 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 LCD1 PF09798.9 ORY42142.1 - 0.19 10.2 0.0 0.37 9.2 0.0 1.4 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF3439 PF11921.8 ORY42143.1 - 0.25 11.3 10.5 0.53 10.3 10.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Glyco_transf_34 PF05637.12 ORY42144.1 - 2.8e-05 24.0 0.0 8.6e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family HEAT_2 PF13646.6 ORY42145.1 - 2.9e-32 110.9 1.2 2.4e-13 50.3 0.2 3.8 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.16 ORY42145.1 - 1.1e-22 78.3 0.0 0.00089 19.7 0.0 6.4 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 ORY42145.1 - 1.3e-05 25.0 0.1 4 7.9 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat Arm PF00514.23 ORY42145.1 - 0.0004 20.3 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 ORY42145.1 - 0.013 16.0 0.4 28 5.4 0.0 3.7 3 2 3 6 6 6 0 HEAT-like repeat Stap_Strp_toxin PF01123.20 ORY42145.1 - 0.083 13.7 0.0 0.21 12.5 0.0 1.7 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, OB-fold domain SH2_2 PF14633.6 ORY42146.1 - 1.5e-57 194.4 0.4 1.5e-57 194.4 0.4 2.8 3 0 0 3 3 3 1 SH2 domain HHH_7 PF14635.6 ORY42146.1 - 6.9e-30 103.5 0.0 1.5e-29 102.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 ORY42146.1 - 8.1e-23 80.9 0.0 3e-22 79.0 0.0 2.1 1 1 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 ORY42146.1 - 7.5e-17 61.8 0.1 5.4e-16 59.0 0.0 2.5 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 ORY42146.1 - 6.2e-11 42.7 17.9 6.2e-11 42.7 17.9 5.7 8 0 0 8 8 8 2 Acidic N-terminal SPT6 SH2 PF00017.24 ORY42146.1 - 1.1e-08 35.0 0.0 4.1e-08 33.2 0.0 2.0 1 0 0 1 1 1 1 SH2 domain HHH_9 PF17674.1 ORY42146.1 - 2e-05 25.4 4.2 4.4e-05 24.3 0.6 3.6 2 1 0 2 2 2 1 HHH domain HHH_3 PF12836.7 ORY42146.1 - 0.00043 20.5 0.0 0.0013 18.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif Tex_YqgF PF16921.5 ORY42146.1 - 0.00072 20.0 0.0 0.0037 17.7 0.0 2.2 1 1 0 1 1 1 1 Tex protein YqgF-like domain LIAS_N PF16881.5 ORY42146.1 - 0.15 12.5 0.8 0.89 10.0 0.8 2.4 1 0 0 1 1 1 0 N-terminal domain of lipoyl synthase of Radical_SAM family Oxidored_FMN PF00724.20 ORY42147.1 - 1.3e-69 235.1 0.0 2e-69 234.4 0.0 1.3 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family CBM_25 PF03423.13 ORY42147.1 - 0.0055 16.9 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) 4HBT_2 PF13279.6 ORY42148.1 - 8.3e-14 52.1 0.3 1e-13 51.9 0.3 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 ORY42148.1 - 0.00022 20.6 2.8 0.0031 16.9 0.3 2.1 1 1 0 2 2 2 2 Acyl-ACP thioesterase 4HBT PF03061.22 ORY42148.1 - 0.13 12.6 0.0 0.39 11.1 0.0 1.8 2 1 0 2 2 2 0 Thioesterase superfamily 4HBT_2 PF13279.6 ORY42149.1 - 7.7e-19 68.4 0.2 1.1e-18 67.9 0.2 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 ORY42149.1 - 1.6e-07 30.9 1.3 4.5e-06 26.1 0.2 2.2 1 1 1 2 2 2 2 Acyl-ACP thioesterase 4HBT PF03061.22 ORY42149.1 - 0.00029 21.1 0.0 0.00081 19.7 0.0 1.7 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_2 PF13279.6 ORY42150.1 - 2.6e-13 50.5 0.1 3.3e-13 50.2 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 ORY42150.1 - 0.00011 21.6 0.3 0.0032 16.8 0.1 2.1 2 0 0 2 2 2 2 Acyl-ACP thioesterase 4HBT PF03061.22 ORY42150.1 - 0.016 15.6 0.0 0.027 14.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily LapA_dom PF06305.11 ORY42151.1 - 0.027 14.3 4.0 0.26 11.1 0.6 2.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF2878 PF11086.8 ORY42151.1 - 0.039 14.2 0.8 0.048 13.9 0.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2878) DUF2148 PF09918.9 ORY42151.1 - 0.06 13.4 0.3 0.11 12.5 0.3 1.5 1 1 0 1 1 1 0 Uncharacterized protein containing a ferredoxin domain (DUF2148) SnoaL_2 PF12680.7 ORY42152.1 - 1.2e-11 45.2 0.0 1.6e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 ORY42152.1 - 3.5e-06 26.8 0.0 6.2e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 ORY42152.1 - 0.011 16.1 0.0 0.015 15.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) COQ7 PF03232.13 ORY42153.1 - 7.2e-68 227.7 0.1 8.5e-68 227.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 ORY42153.1 - 0.029 14.8 0.0 0.094 13.1 0.0 1.7 1 1 0 1 1 1 0 Rubrerythrin TipE PF16972.5 ORY42153.1 - 0.12 11.6 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE PP-binding PF00550.25 ORY42154.1 - 7.8e-13 48.6 1.7 1.1e-12 48.1 1.7 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 ORY42154.1 - 0.018 15.2 0.4 0.024 14.9 0.4 1.2 1 0 0 1 1 1 0 Acyl-carrier DUF1493 PF07377.12 ORY42154.1 - 0.12 12.9 0.1 0.14 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) BolA PF01722.18 ORY42155.1 - 2e-18 66.4 0.0 3.8e-18 65.5 0.0 1.4 1 1 0 1 1 1 1 BolA-like protein PAN_4 PF14295.6 ORY42156.1 - 6.3e-05 22.8 30.5 0.022 14.7 1.2 6.2 6 0 0 6 6 6 4 PAN domain MANEC PF07502.14 ORY42156.1 - 0.012 15.8 1.3 0.012 15.8 1.3 5.7 5 1 1 6 6 6 0 MANEC domain cNMP_binding PF00027.29 ORY42157.1 - 7.9e-22 77.1 0.0 4.3e-14 52.3 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Peptidase_M14 PF00246.24 ORY42159.1 - 2.2e-70 237.7 0.0 2.7e-70 237.5 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Peptidase_C54 PF03416.19 ORY42159.1 - 0.077 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C54 Sugar_tr PF00083.24 ORY42161.1 - 3.5e-117 392.0 21.1 4.3e-117 391.8 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY42161.1 - 1.3e-25 90.1 40.3 4.4e-21 75.2 10.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY42161.1 - 0.00021 19.9 2.9 0.00033 19.2 2.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 ORY42161.1 - 0.0005 18.4 1.1 0.013 13.7 0.0 2.3 2 0 0 2 2 2 2 BT1 family UDPGP PF01704.18 ORY42163.1 - 1.4e-194 646.5 0.0 1.6e-194 646.3 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase CLU PF13236.6 ORY42164.1 - 2e-26 93.2 0.0 3.6e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Clustered mitochondria TPR_12 PF13424.6 ORY42164.1 - 1.1e-16 60.8 8.7 8.4e-13 48.4 1.3 3.8 3 1 0 4 4 4 3 Tetratricopeptide repeat eIF3_p135 PF12807.7 ORY42164.1 - 8.1e-11 42.3 0.4 1.7e-09 38.0 0.4 2.4 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 PH PF00169.29 ORY42164.1 - 0.00083 19.8 0.0 0.0021 18.5 0.0 1.7 1 0 0 1 1 1 1 PH domain TPR_10 PF13374.6 ORY42164.1 - 0.0016 18.3 4.4 12 5.9 0.3 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY42164.1 - 0.02 15.0 10.7 5.8 7.3 0.4 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY42164.1 - 0.083 12.7 3.9 32 4.5 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY42164.1 - 0.29 11.3 1.4 9.5 6.5 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4401 PF14351.6 ORY42165.1 - 0.011 15.1 0.0 0.012 15.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) Ydr279_N PF17745.1 ORY42167.1 - 9.1e-10 38.7 0.0 8.4e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 Ydr279p protein triple barrel domain RNase_H2-Ydr279 PF09468.10 ORY42167.1 - 2.5e-09 37.5 0.1 3.9e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain HD PF01966.22 ORY42168.1 - 0.015 15.5 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 HD domain FHA PF00498.26 ORY42169.1 - 4.6e-15 55.7 0.0 9e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 FHA domain PP1_bind PF15276.6 ORY42169.1 - 4.1e-08 33.4 1.4 4.1e-08 33.4 1.4 3.7 3 0 0 3 3 3 1 Protein phosphatase 1 binding Yop-YscD_cpl PF16697.5 ORY42169.1 - 1.8e-06 28.2 0.0 5.3e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DUF5013 PF16405.5 ORY42171.1 - 0.12 12.7 0.1 0.18 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5013) Protoglobin PF11563.8 ORY42172.1 - 5.8e-23 81.5 0.1 9.8e-23 80.8 0.1 1.4 1 0 0 1 1 1 1 Protoglobin Lipocalin PF00061.23 ORY42172.1 - 0.13 12.5 0.4 0.21 11.8 0.4 1.2 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family DIL PF01843.19 ORY42173.1 - 4.6e-09 36.5 0.0 9.9e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 DIL domain Ank_5 PF13857.6 ORY42174.1 - 2.5e-09 37.2 0.0 6.4e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY42174.1 - 6.2e-06 26.2 0.0 2e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 ORY42174.1 - 2.2e-05 25.0 0.0 5.6e-05 23.7 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY42174.1 - 9.6e-05 22.9 0.0 0.00019 21.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 ORY42174.1 - 0.00083 19.7 0.0 0.0019 18.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ran_BP1 PF00638.18 ORY42176.1 - 9.6e-47 158.3 0.4 1.1e-46 158.0 0.4 1.1 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 ORY42176.1 - 5.7e-05 23.0 0.0 7.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 WH1 domain Hydantoinase_B PF02538.14 ORY42177.1 - 1.1e-219 730.1 0.2 1.5e-219 729.7 0.2 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 ORY42177.1 - 1.3e-97 326.6 0.4 1.3e-97 326.6 0.4 2.5 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 ORY42177.1 - 4e-62 209.1 0.8 1.7e-60 203.8 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Hydrolase_4 PF12146.8 ORY42179.1 - 1.7e-11 43.8 0.0 2.7e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY42179.1 - 4.8e-11 43.7 0.4 6.6e-11 43.2 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY42179.1 - 0.00039 20.1 0.0 0.035 13.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 ORY42179.1 - 0.0054 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3120 PF11318.8 ORY42179.1 - 0.052 13.9 0.0 0.094 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) Carb_anhydrase PF00194.21 ORY42181.1 - 1.2e-44 152.7 1.3 2.1e-44 151.9 1.3 1.3 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Carb_anhydrase PF00194.21 ORY42182.1 - 4.5e-48 164.0 2.5 7.7e-48 163.2 2.4 1.3 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DLH PF01738.18 ORY42183.1 - 9.5e-31 107.0 0.0 1.9e-29 102.8 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 ORY42183.1 - 0.019 14.6 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PNRC PF15365.6 ORY42183.1 - 0.093 12.6 2.0 0.19 11.6 2.0 1.6 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif Carb_anhydrase PF00194.21 ORY42184.1 - 4.4e-29 101.8 1.6 9.8e-29 100.7 1.5 1.5 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Lipase PF00151.19 ORY42184.1 - 0.088 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipase Rhodanese PF00581.20 ORY42186.1 - 8e-11 42.4 0.0 1.1e-10 42.0 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_S41 PF03572.18 ORY42186.1 - 0.005 16.4 0.2 0.0062 16.1 0.2 1.4 1 1 0 1 1 1 1 Peptidase family S41 Rhodanese PF00581.20 ORY42187.1 - 1.2e-11 45.0 0.1 2e-11 44.4 0.1 1.3 1 1 0 1 1 1 1 Rhodanese-like domain Alpha_GJ PF03229.13 ORY42188.1 - 0.064 13.8 1.9 0.098 13.2 1.9 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J 5TM-5TMR_LYT PF07694.12 ORY42188.1 - 0.098 12.2 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 5TMR of 5TMR-LYT FAM163 PF15069.6 ORY42188.1 - 0.22 11.9 0.0 0.33 11.4 0.0 1.4 1 0 0 1 1 1 0 FAM163 family Syndecan PF01034.20 ORY42188.1 - 0.24 11.3 0.2 0.4 10.6 0.2 1.3 1 0 0 1 1 1 0 Syndecan domain Pex14_N PF04695.13 ORY42189.1 - 3.5e-24 86.2 3.9 3.5e-24 86.2 3.9 3.8 2 2 1 3 3 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1664 PF07889.12 ORY42189.1 - 0.0033 17.5 0.1 0.0062 16.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) HlyD_2 PF12700.7 ORY42189.1 - 0.0033 16.2 2.4 0.0048 15.7 2.4 1.1 1 0 0 1 1 1 1 HlyD family secretion protein DUF3584 PF12128.8 ORY42189.1 - 0.0049 14.5 1.9 0.0072 13.9 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Mce4_CUP1 PF11887.8 ORY42189.1 - 0.0066 15.9 0.5 0.012 15.1 0.5 1.3 1 0 0 1 1 1 1 Cholesterol uptake porter CUP1 of Mce4, putative Exonuc_VII_L PF02601.15 ORY42189.1 - 0.024 14.2 2.0 0.034 13.7 2.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit TMPIT PF07851.13 ORY42189.1 - 0.036 13.3 3.1 0.062 12.5 3.1 1.4 1 0 0 1 1 1 0 TMPIT-like protein AIP3 PF03915.13 ORY42189.1 - 0.054 12.6 4.2 0.085 11.9 4.2 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 Tho2 PF11262.8 ORY42189.1 - 0.073 12.3 2.4 0.1 11.7 2.4 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Baculo_PEP_C PF04513.12 ORY42189.1 - 0.089 12.8 2.8 0.21 11.6 2.8 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus PCRF PF03462.18 ORY42189.1 - 0.096 12.5 3.5 1.4 8.8 3.9 2.0 2 0 0 2 2 2 0 PCRF domain GLTSCR1 PF15249.6 ORY42189.1 - 0.11 12.9 1.8 0.19 12.2 1.8 1.4 1 0 0 1 1 1 0 Conserved region of unknown function on GLTSCR protein DUF4407 PF14362.6 ORY42189.1 - 0.15 11.4 5.3 0.21 10.9 4.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5320 PF17253.2 ORY42189.1 - 0.16 13.1 3.0 9 7.4 0.0 2.9 1 1 2 3 3 3 0 Family of unknown function (DUF5320) FAP206 PF12018.8 ORY42189.1 - 0.18 11.3 2.9 0.36 10.3 2.9 1.4 1 0 0 1 1 1 0 Domain of unknown function LMBR1 PF04791.16 ORY42189.1 - 0.2 10.6 0.3 0.26 10.1 0.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein His_kinase PF06580.13 ORY42189.1 - 0.2 12.0 2.8 0.41 11.0 1.7 2.0 1 1 1 2 2 2 0 Histidine kinase Phasin PF05597.11 ORY42189.1 - 0.21 11.6 4.1 0.51 10.3 4.1 1.6 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SKIP_SNW PF02731.15 ORY42189.1 - 0.26 10.9 3.7 0.51 10.0 3.7 1.4 1 0 0 1 1 1 0 SKIP/SNW domain Helo_like_N PF17111.5 ORY42189.1 - 0.38 10.1 6.4 0.21 10.9 0.9 2.1 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins CorA PF01544.18 ORY42189.1 - 0.54 9.5 2.4 0.95 8.7 2.4 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Phage_Mu_Gam PF07352.12 ORY42189.1 - 0.8 9.6 7.9 0.53 10.2 4.6 2.1 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Spc7 PF08317.11 ORY42189.1 - 0.82 8.5 10.8 1.5 7.6 10.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein AMPKBI PF04739.15 ORY42189.1 - 1 9.7 3.8 1.4 9.2 0.6 2.6 2 1 0 2 2 2 0 5'-AMP-activated protein kinase beta subunit, interaction domain Golgin_A5 PF09787.9 ORY42189.1 - 1 8.8 12.5 0.1 12.0 8.0 1.5 2 0 0 2 2 2 0 Golgin subfamily A member 5 AAA_13 PF13166.6 ORY42189.1 - 1.2 7.7 5.4 1.8 7.1 5.4 1.1 1 0 0 1 1 1 0 AAA domain FapA PF03961.13 ORY42189.1 - 2.1 6.9 4.4 3.2 6.3 4.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3450 PF11932.8 ORY42189.1 - 2.3 7.5 11.1 0.3 10.4 6.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) zf-C4H2 PF10146.9 ORY42189.1 - 2.6 8.3 11.9 1.1 9.5 4.0 2.4 2 1 0 2 2 2 0 Zinc finger-containing protein CLZ PF16526.5 ORY42189.1 - 2.6 8.5 6.9 44 4.5 4.7 3.2 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Zw10 PF06248.13 ORY42189.1 - 3 6.3 7.7 4.3 5.8 7.7 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Blt1 PF12754.7 ORY42189.1 - 4.8 7.5 10.9 1.1 9.6 0.4 3.1 3 0 0 3 3 3 0 Blt1 N-terminal domain Rx_N PF18052.1 ORY42189.1 - 7.6 6.9 7.2 11 6.3 2.2 2.9 1 1 2 3 3 3 0 Rx N-terminal domain Ceramidase PF05875.12 ORY42190.1 - 1.1e-07 31.5 15.3 1.6e-06 27.7 15.3 2.0 1 1 0 1 1 1 1 Ceramidase Wzy_C PF04932.15 ORY42191.1 - 0.057 13.1 0.1 0.078 12.6 0.1 1.2 1 0 0 1 1 1 0 O-Antigen ligase F-box-like PF12937.7 ORY42192.1 - 0.0036 17.2 0.2 0.0079 16.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like Steroid_dh PF02544.16 ORY42193.1 - 3e-20 72.7 0.6 3e-20 72.7 0.6 2.0 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Peptidase_M3 PF01432.20 ORY42193.1 - 3.9e-19 69.2 0.0 2.5e-18 66.6 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M2 PF01401.18 ORY42193.1 - 1.9e-08 33.4 0.0 2.6e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Angiotensin-converting enzyme DUF1295 PF06966.12 ORY42193.1 - 1.4e-07 31.3 0.1 2.4e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Peptidase_M32 PF02074.15 ORY42193.1 - 0.016 14.0 0.0 4 6.1 0.0 2.3 2 0 0 2 2 2 0 Carboxypeptidase Taq (M32) metallopeptidase Peptidase_M91 PF14891.6 ORY42193.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Effector protein DUF4106 PF13388.6 ORY42194.1 - 8.6 5.5 9.8 9.7 5.3 9.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Muskelin_N PF06588.11 ORY42195.1 - 2.3e-58 197.4 0.5 5.8e-45 153.6 0.0 2.3 1 1 1 2 2 2 2 Muskelin N-terminus Kelch_3 PF13415.6 ORY42195.1 - 1.2e-18 67.0 2.7 2.6e-10 40.3 0.0 5.7 5 1 1 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.25 ORY42195.1 - 2.7e-13 49.2 4.6 2.3e-06 27.1 0.2 3.9 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 ORY42195.1 - 1.8e-09 37.5 4.6 0.0016 18.6 0.1 5.0 4 1 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 ORY42195.1 - 1.2e-07 31.6 6.6 0.0031 17.5 0.0 4.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY42195.1 - 1.5e-05 24.7 3.9 0.014 15.4 0.4 4.2 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.6 ORY42195.1 - 0.00024 21.0 3.9 3.1 7.9 0.0 5.2 4 1 0 4 4 4 1 Kelch motif Reovirus_Mu2 PF07781.11 ORY42195.1 - 0.25 9.7 0.0 0.36 9.1 0.0 1.1 1 0 0 1 1 1 0 Reovirus minor core protein Mu-2 LRR_4 PF12799.7 ORY42196.1 - 8.9e-11 41.9 10.9 0.00018 21.8 0.3 3.4 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY42196.1 - 2e-07 30.6 4.2 3e-05 23.7 2.0 3.1 1 1 2 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 ORY42196.1 - 3e-05 23.7 7.8 0.85 9.8 0.0 4.8 5 0 0 5 5 5 2 Leucine Rich repeat LRR_1 PF00560.33 ORY42196.1 - 0.00054 20.1 7.6 4.9 8.1 0.1 5.1 5 0 0 5 5 5 2 Leucine Rich Repeat Syndecan PF01034.20 ORY42196.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain FNIP PF05725.12 ORY42196.1 - 2.3 8.5 8.9 4.8 7.4 0.1 3.2 3 1 0 3 3 3 0 FNIP Repeat LRR_4 PF12799.7 ORY42197.1 - 0.0011 19.3 5.1 0.76 10.3 0.2 2.9 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY42197.1 - 0.04 14.5 2.6 22 6.1 0.1 3.9 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_8 PF13855.6 ORY42197.1 - 0.13 12.0 4.3 1.4 8.7 0.9 2.9 1 1 1 2 2 2 0 Leucine rich repeat WD40 PF00400.32 ORY42198.1 - 2.3e-12 47.2 6.2 7.2e-06 26.6 0.0 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY42198.1 - 0.083 13.2 0.0 1.8 8.9 0.0 3.0 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain adh_short_C2 PF13561.6 ORY42199.1 - 1.1e-52 179.0 3.3 1.5e-52 178.5 3.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY42199.1 - 1.9e-44 151.5 3.1 3.1e-44 150.8 3.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY42199.1 - 3.9e-10 39.9 1.1 7e-10 39.1 1.1 1.5 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ORY42199.1 - 0.0048 16.8 0.7 0.0077 16.1 0.7 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 ORY42199.1 - 0.053 13.6 0.1 0.086 12.9 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4808 PF16066.5 ORY42200.1 - 0.14 12.7 0.1 0.23 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4808) PKD_channel PF08016.12 ORY42200.1 - 0.43 9.2 6.2 0.26 9.9 1.0 2.0 1 1 0 2 2 2 0 Polycystin cation channel LrgA PF03788.14 ORY42200.1 - 1.6 8.8 11.0 1.5 8.8 3.5 2.2 1 1 1 2 2 2 0 LrgA family DUF455 PF04305.14 ORY42201.1 - 3.5e-92 308.4 0.1 4.2e-92 308.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 ORY42201.1 - 3.4e-07 30.1 0.0 9.9e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 ORY42201.1 - 0.12 12.3 0.0 0.37 10.8 0.0 1.7 1 1 0 1 1 1 0 Rieske-like [2Fe-2S] domain Pterin_4a PF01329.19 ORY42202.1 - 1.2e-28 99.1 0.3 1.4e-28 98.9 0.3 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase SLATT_fungal PF18142.1 ORY42203.1 - 0.11 12.5 0.3 0.24 11.4 0.3 1.7 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain LRR_4 PF12799.7 ORY42204.1 - 4e-12 46.1 17.9 0.00018 21.8 0.2 4.6 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY42204.1 - 1.6e-10 40.6 17.2 0.0015 18.3 1.0 4.3 2 2 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.6 ORY42204.1 - 4.9e-07 29.3 12.9 0.39 10.9 0.0 6.6 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 ORY42204.1 - 5.2e-07 29.3 20.3 1.5 9.7 0.2 7.4 7 1 0 7 7 7 4 Leucine Rich Repeat FNIP PF05725.12 ORY42204.1 - 0.002 18.3 3.5 0.002 18.3 3.5 4.7 3 2 2 5 5 5 2 FNIP Repeat adh_short_C2 PF13561.6 ORY42206.1 - 1e-51 175.8 7.8 1.3e-49 168.9 7.8 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY42206.1 - 4.8e-40 137.1 3.0 6.1e-40 136.8 3.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY42206.1 - 2.8e-07 30.6 0.7 4.4e-07 30.0 0.7 1.3 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ORY42206.1 - 0.0034 17.3 0.5 0.0062 16.4 0.5 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain OrsD PF12013.8 ORY42207.1 - 0.014 15.8 0.1 0.042 14.3 0.1 1.8 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF3430 PF11912.8 ORY42208.1 - 0.00024 21.2 44.4 0.15 12.1 15.6 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3430) TNFR_16_TM PF18422.1 ORY42208.1 - 0.04 13.9 0.1 0.077 13.0 0.1 1.4 1 0 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Syndecan PF01034.20 ORY42208.1 - 0.056 13.4 0.1 0.1 12.5 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain SAM_PNT PF02198.16 ORY42209.1 - 2.3e-05 24.3 0.0 4.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain MOLO1 PF17175.4 ORY42210.1 - 0.088 12.9 0.2 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 Modulator of levamisole receptor-1 AF0941-like PF14591.6 ORY42211.1 - 0.12 13.0 0.0 0.17 12.5 0.0 1.2 1 0 0 1 1 1 0 AF0941-like DUF3430 PF11912.8 ORY42212.1 - 3.4e-05 24.0 32.4 0.00013 22.1 7.5 3.9 1 1 2 3 3 3 3 Protein of unknown function (DUF3430) SAM_PNT PF02198.16 ORY42213.1 - 0.00091 19.1 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain DUF3430 PF11912.8 ORY42213.1 - 0.0091 16.1 12.3 0.0091 16.1 12.3 3.3 1 1 2 3 3 3 2 Protein of unknown function (DUF3430) Inhibitor_I36 PF03995.13 ORY42213.1 - 0.051 13.5 7.4 0.52 10.3 1.1 3.4 2 1 1 3 3 3 0 Peptidase inhibitor family I36 Syndecan PF01034.20 ORY42213.1 - 0.16 11.9 0.1 0.34 10.9 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain DUF4729 PF15866.5 ORY42214.1 - 0.0087 15.4 0.4 0.019 14.3 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4729) SAM_PNT PF02198.16 ORY42215.1 - 4.8e-07 29.7 0.1 9e-07 28.8 0.1 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_1 PF00536.30 ORY42215.1 - 2.9e-06 27.6 0.2 4.6e-06 27.0 0.2 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Urb2 PF10441.9 ORY42216.1 - 2.8e-14 53.5 2.4 2.7e-12 47.1 0.2 2.5 3 0 0 3 3 3 2 Urb2/Npa2 family AAA_lid_11 PF18198.1 ORY42217.1 - 0.064 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain Shisa PF13908.6 ORY42218.1 - 0.0047 17.2 0.4 0.0085 16.4 0.4 1.5 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator WBP-1 PF11669.8 ORY42218.1 - 0.034 14.8 0.2 0.034 14.8 0.2 1.7 2 0 0 2 2 2 0 WW domain-binding protein 1 Rrn6 PF10214.9 ORY42218.1 - 0.17 10.3 2.1 0.21 10.0 2.1 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor IBN_N PF03810.19 ORY42219.1 - 0.19 11.6 0.0 0.39 10.7 0.0 1.4 1 0 0 1 1 1 0 Importin-beta N-terminal domain Polysacc_deac_1 PF01522.21 ORY42220.1 - 8.9e-23 80.5 0.0 1.2e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase 6PGD PF00393.19 ORY42221.1 - 6.8e-94 314.5 0.7 2e-46 158.7 0.3 2.9 1 1 1 2 2 2 2 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 ORY42221.1 - 1.7e-51 174.5 0.0 2.7e-51 173.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_16 PF10294.9 ORY42221.1 - 0.00038 20.2 0.0 0.00066 19.5 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase NAD_binding_11 PF14833.6 ORY42221.1 - 0.0097 16.1 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 ORY42221.1 - 0.027 15.1 0.1 0.061 13.9 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PrmA PF06325.13 ORY42221.1 - 0.041 13.3 0.1 0.075 12.4 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) SWIM PF04434.17 ORY42222.1 - 6.7e-08 32.0 0.9 1.3e-07 31.1 0.9 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-RING_2 PF13639.6 ORY42222.1 - 1.1e-05 25.6 7.9 1.1e-05 25.6 7.9 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 ORY42222.1 - 0.00029 20.7 7.0 0.00029 20.7 7.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_1 PF14446.6 ORY42222.1 - 0.00029 20.7 2.8 0.00029 20.7 2.8 2.4 2 1 1 3 3 2 1 Prokaryotic RING finger family 1 Zf_RING PF16744.5 ORY42222.1 - 0.00054 20.0 3.3 0.0012 19.0 3.3 1.6 1 0 0 1 1 1 1 KIAA1045 RING finger PHD PF00628.29 ORY42222.1 - 0.00056 19.7 8.4 0.0012 18.7 8.4 1.6 1 0 0 1 1 1 1 PHD-finger zf-RING_UBOX PF13445.6 ORY42222.1 - 0.0032 17.5 3.0 0.0087 16.1 3.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-PHD-like PF15446.6 ORY42222.1 - 0.0099 15.5 3.8 0.022 14.4 3.8 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 ORY42222.1 - 0.016 15.1 8.4 0.018 14.9 4.7 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_4 PF14570.6 ORY42222.1 - 0.021 14.6 5.1 0.021 14.6 5.1 1.7 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 ORY42222.1 - 0.027 14.6 5.7 0.027 14.6 5.7 2.1 2 0 0 2 2 2 0 FANCL C-terminal domain FYVE_2 PF02318.16 ORY42222.1 - 0.028 14.6 1.5 0.028 14.6 1.5 1.6 2 0 0 2 2 2 0 FYVE-type zinc finger DUF2318 PF10080.9 ORY42222.1 - 0.071 13.2 3.9 4.2 7.5 2.0 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) RINGv PF12906.7 ORY42222.1 - 0.15 12.2 9.6 0.33 11.1 9.6 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4 PF00097.25 ORY42222.1 - 7.7 6.5 13.4 0.084 12.8 5.6 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Hist_deacetyl PF00850.19 ORY42223.1 - 8.4e-72 242.2 0.0 1.1e-71 241.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain AA_permease PF00324.21 ORY42224.1 - 3.5e-63 213.9 30.4 3.2e-50 171.1 20.3 2.2 1 1 0 2 2 2 2 Amino acid permease RseC_MucC PF04246.12 ORY42224.1 - 3.9 7.4 5.6 13 5.8 5.6 1.9 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Synaptobrevin PF00957.21 ORY42225.1 - 2e-10 40.3 0.6 3.5e-10 39.5 0.6 1.4 1 0 0 1 1 1 1 Synaptobrevin ubiquitin PF00240.23 ORY42226.1 - 0.082 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family HEAT PF02985.22 ORY42229.1 - 0.0003 20.8 0.1 0.13 12.6 0.0 2.6 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.6 ORY42229.1 - 0.0082 16.5 0.1 0.025 15.0 0.1 1.7 1 1 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.6 ORY42229.1 - 0.08 13.5 0.1 6 7.5 0.0 2.4 2 0 0 2 2 2 0 HEAT-like repeat Polysacc_deac_1 PF01522.21 ORY42230.1 - 3.7e-30 104.4 0.0 5.4e-30 103.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORY42230.1 - 0.075 12.2 0.0 0.094 11.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 CorA PF01544.18 ORY42231.1 - 0.037 13.3 5.4 0.045 13.1 5.4 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Ndc80_HEC PF03801.13 ORY42232.1 - 7.9e-52 174.9 0.0 1.6e-51 173.9 0.0 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family DUF5595 PF18077.1 ORY42232.1 - 8.8e-13 48.1 0.5 8.8e-13 48.1 0.5 3.5 3 1 1 4 4 4 1 Domain of unknown function (DUF5595) HsbA PF12296.8 ORY42232.1 - 0.07 13.6 3.8 0.4 11.1 0.0 3.2 3 0 0 3 3 3 0 Hydrophobic surface binding protein A DUF1759 PF03564.15 ORY42232.1 - 0.25 11.3 8.9 3.8 7.4 0.5 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1759) NuA4 PF09340.10 ORY42232.1 - 0.73 9.7 4.3 1.4 8.9 1.2 2.9 2 0 0 2 2 2 0 Histone acetyltransferase subunit NuA4 DUF948 PF06103.11 ORY42232.1 - 1.8 8.8 8.8 35 4.7 0.0 4.0 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) CorA PF01544.18 ORY42232.1 - 2 7.7 15.7 3.4 6.9 4.6 2.4 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF3450 PF11932.8 ORY42232.1 - 2.3 7.5 22.1 1 8.6 2.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) SPT_ssu-like PF11779.8 ORY42233.1 - 6.3e-19 67.3 5.1 8.5e-19 66.9 5.1 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like SPT_ssu-like PF11779.8 ORY42234.1 - 2.3e-11 43.1 0.6 3.1e-11 42.7 0.6 1.3 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like X PF00739.19 ORY42234.1 - 0.23 11.6 0.0 0.24 11.5 0.0 1.1 1 0 0 1 1 1 0 Trans-activation protein X AIG2_2 PF13772.6 ORY42235.1 - 7.8e-06 26.2 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family GGACT PF06094.12 ORY42235.1 - 2.2e-05 25.0 0.0 2.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like EF-hand_8 PF13833.6 ORY42235.1 - 0.00084 19.1 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair Ribosomal_L7Ae PF01248.26 ORY42236.1 - 9.5e-26 89.4 3.2 1.3e-25 88.9 3.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Fam20C PF06702.12 ORY42236.1 - 0.0012 18.7 0.1 0.0017 18.3 0.1 1.1 1 0 0 1 1 1 1 Golgi casein kinase, C-terminal, Fam20 PSK_trans_fac PF07704.11 ORY42236.1 - 0.087 13.6 0.6 0.12 13.2 0.6 1.3 1 0 0 1 1 1 0 Rv0623-like transcription factor Ribonuc_L-PSP PF01042.21 ORY42237.1 - 1.3e-20 73.6 0.0 1.5e-20 73.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF630 PF04783.12 ORY42237.1 - 0.038 14.2 0.0 0.65 10.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF630) P22_AR_C PF10548.9 ORY42237.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 P22AR C-terminal domain Aa_trans PF01490.18 ORY42238.1 - 8.2e-86 288.3 29.2 1e-85 288.0 29.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 ORY42238.1 - 2.5e-06 26.8 14.9 2.5e-06 26.8 14.9 2.0 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family DUF4271 PF14093.6 ORY42238.1 - 0.0054 16.7 0.2 0.0054 16.7 0.2 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4271) DUF4731 PF15875.5 ORY42238.1 - 4.8 7.4 8.8 1.3 9.3 0.8 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4731) Glyco_hydro_18 PF00704.28 ORY42239.1 - 7.7e-09 35.7 0.0 8.8e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SAM_PNT PF02198.16 ORY42240.1 - 0.03 14.3 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain SAM_1 PF00536.30 ORY42240.1 - 0.031 14.7 0.0 0.06 13.8 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 ORY42240.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF677 PF05055.12 ORY42241.1 - 0.057 12.3 1.0 0.08 11.8 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) SAM_PNT PF02198.16 ORY42242.1 - 9.3e-05 22.3 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_1 PF00536.30 ORY42242.1 - 0.00028 21.3 0.1 0.00043 20.7 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DAP10 PF07213.11 ORY42242.1 - 0.0064 16.4 1.6 0.017 15.0 0.3 2.3 2 0 0 2 2 2 1 DAP10 membrane protein SAM_PNT PF02198.16 ORY42243.1 - 2.3e-07 30.7 0.2 4.1e-07 29.9 0.2 1.3 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_1 PF00536.30 ORY42243.1 - 2.5e-05 24.6 0.2 3.7e-05 24.1 0.2 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 ORY42243.1 - 0.00027 21.0 0.1 0.00044 20.3 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Syndecan PF01034.20 ORY42243.1 - 0.013 15.4 0.1 0.033 14.1 0.1 1.6 1 0 0 1 1 1 0 Syndecan domain SAM_PNT PF02198.16 ORY42244.1 - 2.4e-05 24.2 0.1 5.2e-05 23.1 0.1 1.6 1 1 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.17 ORY42244.1 - 0.00078 19.5 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORY42244.1 - 0.014 15.8 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 ORY42244.1 - 0.023 14.9 0.1 0.075 13.3 0.0 1.8 2 0 0 2 2 2 0 Ste50p, sterile alpha motif Fibrinogen_aC PF12160.8 ORY42244.1 - 0.03 14.2 2.5 0.42 10.5 0.2 2.8 2 0 0 2 2 2 0 Fibrinogen alpha C domain SAM_PNT PF02198.16 ORY42245.1 - 0.00026 20.9 0.0 0.00045 20.1 0.0 1.3 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_1 PF00536.30 ORY42245.1 - 0.024 15.1 0.0 0.044 14.2 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 ORY42246.1 - 1.3e-06 28.2 0.0 2.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_1 PF00536.30 ORY42246.1 - 0.001 19.4 0.0 0.0017 18.7 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 ORY42246.1 - 0.16 12.1 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORY42249.1 - 7.1e-06 26.4 0.0 1.5e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 ORY42249.1 - 1.9e-05 24.5 0.0 3.8e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.17 ORY42249.1 - 0.024 14.7 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 ORY42250.1 - 1.2e-05 25.1 0.0 2.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_1 PF00536.30 ORY42250.1 - 0.0011 19.3 0.0 0.002 18.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 ORY42250.1 - 0.034 14.4 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif EamA PF00892.20 ORY42251.1 - 1.1e-07 32.1 10.9 3.5e-06 27.2 10.9 2.0 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 ORY42251.1 - 0.00053 20.0 1.8 0.00083 19.4 0.8 1.6 1 1 0 2 2 2 1 Putative transmembrane family 234 Multi_Drug_Res PF00893.19 ORY42251.1 - 0.012 16.3 0.7 0.023 15.4 0.7 1.5 1 0 0 1 1 1 0 Small Multidrug Resistance protein DUF4357 PF14267.6 ORY42251.1 - 0.35 10.9 3.0 0.75 9.8 3.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) DUF3471 PF11954.8 ORY42255.1 - 1.8e-05 25.2 0.0 2.7e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3471) SKG6 PF08693.10 ORY42256.1 - 0.035 13.5 0.0 0.035 13.5 0.0 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain CD34_antigen PF06365.12 ORY42256.1 - 0.19 11.3 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Glycos_transf_2 PF00535.26 ORY42257.1 - 2.9e-06 27.2 0.0 4.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF3731 PF12531.8 ORY42257.1 - 0.087 12.6 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 DNA-K related protein Polysacc_deac_1 PF01522.21 ORY42258.1 - 8.3e-28 96.8 0.0 1.3e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORY42258.1 - 0.0031 16.8 0.1 0.012 14.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 Polysacc_deac_1 PF01522.21 ORY42259.1 - 2.2e-17 63.1 0.0 4.6e-17 62.1 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide deacetylase GAT PF03127.14 ORY42260.1 - 4.5e-11 42.9 4.1 5.7e-11 42.6 3.0 1.7 2 0 0 2 2 2 1 GAT domain VHS PF00790.19 ORY42260.1 - 1.6e-09 37.7 0.0 3.2e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 VHS domain DDE_Tnp_Tn3 PF01526.17 ORY42260.1 - 0.051 12.3 0.0 0.074 11.8 0.0 1.2 1 0 0 1 1 1 0 Tn3 transposase DDE domain Polysacc_deac_1 PF01522.21 ORY42261.1 - 2.4e-20 72.7 0.0 3.6e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORY42261.1 - 0.00011 21.5 0.0 0.00016 21.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 MIP-T3 PF10243.9 ORY42261.1 - 0.076 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CH-like domain MGC-24 PF05283.11 ORY42261.1 - 0.17 12.3 4.6 0.27 11.7 4.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pribosyltran_N PF13793.6 ORY42263.1 - 3.1e-47 159.3 0.9 4.1e-46 155.7 0.2 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 ORY42263.1 - 6.1e-42 143.7 1.2 3.3e-36 125.1 0.2 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 ORY42263.1 - 4.9e-16 58.6 4.5 4e-15 55.7 1.7 2.4 2 1 0 2 2 2 2 Phosphoribosyl transferase domain ABC_tran PF00005.27 ORY42264.1 - 5.7e-57 192.1 0.1 6.5e-30 104.4 0.2 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORY42264.1 - 9.3e-46 156.7 18.7 2.2e-24 86.6 5.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_29 PF13555.6 ORY42264.1 - 2.1e-08 33.8 1.2 0.0026 17.5 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ORY42264.1 - 5.7e-08 33.1 0.0 0.00017 21.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 ORY42264.1 - 2.2e-07 31.0 0.0 0.14 11.9 0.0 4.1 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORY42264.1 - 3.5e-06 27.5 0.1 0.049 14.0 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 ORY42264.1 - 2.3e-05 23.9 0.0 0.045 13.2 0.0 3.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain DEAD PF00270.29 ORY42264.1 - 0.00013 21.7 0.1 0.12 12.1 0.0 2.7 2 1 0 2 2 2 2 DEAD/DEAH box helicase AAA_30 PF13604.6 ORY42264.1 - 0.00051 19.8 0.1 0.085 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ORY42264.1 - 0.00092 19.2 0.8 1.7 8.5 0.1 3.0 3 0 0 3 3 2 2 RsgA GTPase G-alpha PF00503.20 ORY42264.1 - 0.0031 16.7 0.1 0.45 9.6 0.1 2.3 2 0 0 2 2 2 1 G-protein alpha subunit Zeta_toxin PF06414.12 ORY42264.1 - 0.0095 15.2 0.0 3.4 6.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin SbcCD_C PF13558.6 ORY42264.1 - 0.041 14.1 0.1 3.1 8.1 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 ORY42264.1 - 0.06 13.4 0.1 0.98 9.5 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_25 PF13481.6 ORY42264.1 - 0.064 12.8 1.4 5.6 6.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 ORY42264.1 - 0.075 13.6 0.0 1.2 9.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.6 ORY42264.1 - 0.091 11.8 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) NTPase_1 PF03266.15 ORY42264.1 - 0.1 12.5 0.0 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_23 PF13476.6 ORY42264.1 - 0.18 12.3 2.5 5.7 7.4 0.3 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORY42264.1 - 0.28 11.5 2.7 2.2 8.6 0.2 3.3 3 1 0 3 3 2 0 AAA domain ADC PF06314.11 ORY42266.1 - 8e-08 32.1 0.0 2.3e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 Acetoacetate decarboxylase (ADC) RP-C_C PF11800.8 ORY42267.1 - 3 7.9 7.3 0.89 9.6 4.0 1.6 1 1 1 2 2 2 0 Replication protein C C-terminal region HSBP1 PF06825.12 ORY42267.1 - 7.1 6.6 7.0 0.95 9.4 1.0 2.4 2 1 0 2 2 2 0 Heat shock factor binding protein 1 DJ-1_PfpI PF01965.24 ORY42270.1 - 5.3e-17 62.1 0.0 1e-16 61.2 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORY42270.1 - 4.9e-09 36.2 0.3 0.00091 19.0 0.0 2.3 2 1 0 2 2 2 2 ThiJ/PfpI family-like Glycos_transf_4 PF00953.21 ORY42271.1 - 2.3e-32 112.2 15.0 2.3e-32 112.2 15.0 2.2 3 0 0 3 3 3 1 Glycosyl transferase family 4 EAP30 PF04157.16 ORY42272.1 - 0.064 12.5 0.1 0.15 11.4 0.1 1.5 1 0 0 1 1 1 0 EAP30/Vps36 family DJ-1_PfpI PF01965.24 ORY42273.1 - 8.6e-17 61.4 0.0 1.5e-16 60.6 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORY42273.1 - 3e-09 36.8 0.2 0.00091 19.0 0.0 2.4 2 1 0 2 2 2 2 ThiJ/PfpI family-like MFS_1 PF07690.16 ORY42274.1 - 1.7e-16 60.1 41.9 6.5e-10 38.5 28.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 ORY42274.1 - 6.2e-07 29.3 10.6 6.2e-07 29.3 10.6 2.9 2 2 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 ORY42275.1 - 5.8e-09 35.3 12.2 7.3e-09 35.0 12.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ORY42275.1 - 0.06 12.2 5.1 0.099 11.5 4.4 1.6 1 1 0 1 1 1 0 MFS_1 like family DMT_YdcZ PF04657.13 ORY42275.1 - 0.2 11.9 9.9 0.74 10.1 5.2 2.3 1 1 0 2 2 2 0 Putative inner membrane exporter, YdcZ Wtap PF17098.5 ORY42278.1 - 1.3e-12 47.9 14.2 1.9e-12 47.4 14.2 1.3 1 0 0 1 1 1 1 WTAP/Mum2p family DUF641 PF04859.12 ORY42278.1 - 0.0034 17.7 10.6 0.091 13.1 0.1 3.2 2 1 0 3 3 3 1 Plant protein of unknown function (DUF641) SlyX PF04102.12 ORY42278.1 - 0.008 16.8 9.1 0.018 15.6 0.4 3.3 3 0 0 3 3 3 1 SlyX DMPK_coil PF08826.10 ORY42278.1 - 0.019 15.0 2.1 0.019 15.0 2.1 3.1 3 1 1 4 4 4 0 DMPK coiled coil domain like IFT20 PF14931.6 ORY42278.1 - 0.027 14.6 1.3 0.027 14.6 1.3 2.8 2 1 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 Herpes_BLRF2 PF05812.12 ORY42278.1 - 0.064 13.4 12.0 0.24 11.6 0.4 3.2 1 1 2 3 3 3 0 Herpesvirus BLRF2 protein DivIC PF04977.15 ORY42278.1 - 0.14 12.0 0.2 0.14 12.0 0.2 2.8 3 0 0 3 3 3 0 Septum formation initiator Sas10_Utp3 PF04000.15 ORY42278.1 - 0.14 12.8 6.3 0.056 14.1 3.0 2.0 2 0 0 2 2 2 0 Sas10/Utp3/C1D family Pneumo_att_G PF05539.11 ORY42278.1 - 0.33 10.5 5.9 0.39 10.3 5.9 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G FliJ PF02050.16 ORY42278.1 - 0.4 10.9 12.5 0.39 11.0 1.4 3.0 3 0 0 3 3 3 0 Flagellar FliJ protein Exonuc_VII_L PF02601.15 ORY42278.1 - 0.49 9.9 7.7 0.7 9.4 7.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ly49 PF08391.10 ORY42278.1 - 0.54 10.6 3.7 0.37 11.1 0.2 2.2 2 1 0 2 2 2 0 Ly49-like protein, N-terminal region DUF3573 PF12097.8 ORY42278.1 - 0.6 8.9 4.2 0.91 8.3 2.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Occludin_ELL PF07303.13 ORY42278.1 - 1.1 10.0 5.9 2.3 9.0 1.2 2.3 2 0 0 2 2 2 0 Occludin homology domain TFIIA PF03153.13 ORY42278.1 - 1.6 8.6 8.9 1.8 8.5 8.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fib_alpha PF08702.10 ORY42278.1 - 2.5 8.3 9.0 1.3 9.2 1.4 2.5 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family zn-ribbon_14 PF16503.5 ORY42280.1 - 1.7e-17 62.6 3.6 1.7e-17 62.6 3.6 4.0 5 0 0 5 5 5 1 Zinc-ribbon ATP_bind_3 PF01171.20 ORY42280.1 - 2.7e-13 50.1 0.0 4.8e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 PP-loop family RecR PF02132.15 ORY42280.1 - 0.034 13.7 1.6 0.034 13.7 1.6 3.1 4 0 0 4 4 4 0 RecR protein ThiI PF02568.14 ORY42280.1 - 0.059 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Dak1 PF02733.17 ORY42281.1 - 2.1e-79 266.7 6.0 2.1e-78 263.4 6.0 2.0 1 1 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 ORY42281.1 - 9.8e-45 152.6 0.8 2.4e-44 151.3 0.8 1.7 1 0 0 1 1 1 1 DAK2 domain GCP_C_terminal PF04130.13 ORY42282.1 - 1.3e-42 146.3 0.1 2.8e-42 145.3 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 ORY42282.1 - 1.8e-36 126.4 0.1 3.6e-36 125.4 0.1 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal UPF1_Zn_bind PF09416.10 ORY42284.1 - 2.6e-67 225.5 0.0 4e-67 224.9 0.0 1.3 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) RVT_3 PF13456.6 ORY42284.1 - 3.1e-12 46.4 0.0 3.7e-10 39.7 0.0 2.5 2 0 0 2 2 2 1 Reverse transcriptase-like DUF5599 PF18141.1 ORY42284.1 - 9.4e-07 29.0 0.0 1.9e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) Ribosomal_S27e PF01667.17 ORY42284.1 - 3.9 7.2 6.6 1.8 8.3 2.0 2.6 3 0 0 3 3 3 0 Ribosomal protein S27 Myc_N PF01056.18 ORY42284.1 - 4.6 7.1 7.2 1.2 9.0 3.6 1.6 1 1 0 1 1 1 0 Myc amino-terminal region Gly-zipper_YMGG PF13441.6 ORY42285.1 - 0.054 13.2 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper MatE PF01554.18 ORY42286.1 - 0.031 13.9 1.7 0.031 13.9 1.7 1.7 2 0 0 2 2 2 0 MatE Chlorosome_CsmC PF11098.8 ORY42286.1 - 0.15 12.0 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C DUF5464 PF17552.2 ORY42286.1 - 7.3 6.9 8.1 0.74 10.1 2.3 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5464) MFS_1 PF07690.16 ORY42287.1 - 2.1e-24 86.2 34.7 8.3e-13 48.0 11.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 ORY42287.1 - 5.7e-09 35.9 10.0 5.7e-09 35.9 10.0 2.7 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 ORY42287.1 - 1.8e-05 23.8 17.7 2.5e-05 23.3 1.6 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter PUCC PF03209.15 ORY42287.1 - 0.00038 19.6 7.2 0.002 17.2 6.3 2.2 1 1 0 1 1 1 1 PUCC protein TRI12 PF06609.13 ORY42287.1 - 0.0059 15.1 5.4 0.0096 14.4 0.2 2.4 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 ORY42288.1 - 5.1e-14 52.0 18.9 1.8e-11 43.6 11.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3430 PF11912.8 ORY42289.1 - 0.00014 21.9 43.0 0.0021 18.1 5.9 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3430) Yip1 PF04893.17 ORY42289.1 - 0.055 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Yip1 domain S1FA PF04689.13 ORY42289.1 - 0.1 12.8 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA zf-PARP PF00645.18 ORY42291.1 - 1.4e-09 38.7 0.0 3.8e-09 37.3 0.0 1.7 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DnaJ PF00226.31 ORY42291.1 - 4.3e-06 26.8 0.0 8.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain BRCT PF00533.26 ORY42291.1 - 1.1e-05 25.7 0.0 2.3e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 ORY42291.1 - 7.2e-05 22.7 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain Ribosomal_L3 PF00297.22 ORY42292.1 - 5.3e-22 78.3 0.8 1.1e-18 67.3 0.6 2.0 1 1 1 2 2 2 2 Ribosomal protein L3 UbiA PF01040.18 ORY42293.1 - 8.7e-48 162.8 19.6 1.2e-47 162.4 19.6 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF4419 PF14388.6 ORY42294.1 - 1.2e-102 343.4 0.5 1.4e-102 343.2 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Glyco_hydro_85 PF03644.13 ORY42295.1 - 2.6e-91 306.2 0.4 4.1e-91 305.5 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 F-box PF00646.33 ORY42296.1 - 0.029 14.2 1.5 0.095 12.6 0.8 2.3 2 0 0 2 2 2 0 F-box domain HECT PF00632.25 ORY42297.1 - 8.1e-100 334.3 0.4 1.2e-99 333.7 0.4 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 ORY42297.1 - 5.1e-34 116.0 10.5 4.3e-11 42.7 0.1 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.30 ORY42297.1 - 3.3e-18 65.9 0.6 9.3e-18 64.4 0.1 2.1 2 0 0 2 2 2 1 C2 domain CAF1 PF04857.20 ORY42298.1 - 2.1e-56 191.5 0.0 7.7e-31 107.4 0.0 2.1 1 1 1 2 2 2 2 CAF1 family ribonuclease Torus PF16131.5 ORY42298.1 - 0.0017 19.0 0.1 0.0035 18.0 0.1 1.4 1 0 0 1 1 1 1 Torus domain zf-CCCH PF00642.24 ORY42298.1 - 0.029 14.3 1.8 0.048 13.6 1.8 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY42298.1 - 0.04 14.0 0.6 0.076 13.1 0.6 1.5 1 0 0 1 1 1 0 Zinc finger domain zf-C2H2 PF00096.26 ORY42301.1 - 3.4e-08 33.5 11.1 3.5e-05 24.0 0.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 ORY42301.1 - 3.1e-07 30.5 2.9 0.0015 18.7 0.4 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 ORY42301.1 - 4.9e-07 30.0 9.2 0.0062 17.3 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ORY42301.1 - 0.002 18.5 1.2 0.0099 16.2 0.0 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 ORY42301.1 - 0.019 15.4 1.5 0.019 15.4 1.5 2.6 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_11 PF16622.5 ORY42301.1 - 0.34 10.7 2.8 4.8 7.0 0.0 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type HIM1 PF08732.10 ORY42303.1 - 0.044 13.3 0.3 0.16 11.5 0.2 1.9 2 0 0 2 2 2 0 HIM1 IMUP PF15761.5 ORY42303.1 - 5.4 7.8 11.5 3 8.6 8.9 1.9 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF4413 PF14372.6 ORY42304.1 - 0.084 13.3 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) NUDE_C PF04880.13 ORY42305.1 - 0.71 10.3 5.0 0.83 10.1 5.0 1.1 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region SSFA2_C PF14723.6 ORY42305.1 - 1.3 8.9 4.1 1.4 8.8 4.1 1.0 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus DUF3987 PF13148.6 ORY42306.1 - 2e-09 36.9 0.0 6.1e-07 28.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) DUF684 PF05075.14 ORY42308.1 - 0.063 12.3 0.1 0.085 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF684) zf-C2H2 PF00096.26 ORY42309.1 - 1.1e-09 38.2 7.3 0.00015 22.0 1.4 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY42309.1 - 3.7e-09 36.7 6.4 0.00071 20.2 0.9 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY42309.1 - 3e-07 30.3 0.4 0.0028 17.6 0.1 3.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-met PF12874.7 ORY42309.1 - 1.6e-05 25.1 0.3 0.013 15.9 0.0 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 ORY42309.1 - 5.5e-05 23.4 1.9 0.0012 19.2 0.0 3.0 3 0 0 3 3 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY42309.1 - 0.0001 22.5 1.5 0.022 15.0 0.2 2.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 ORY42309.1 - 0.0001 22.1 13.6 0.00035 20.4 1.2 3.2 4 0 0 4 4 4 2 zinc-finger of a C2HC-type zf-C2H2_3rep PF18868.1 ORY42309.1 - 0.0014 19.3 1.4 0.059 14.1 0.1 2.4 2 0 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf_ZIC PF18366.1 ORY42309.1 - 0.0024 17.9 2.7 0.24 11.5 0.2 2.7 3 0 0 3 3 2 1 Zic proteins zinc finger domain zf-Di19 PF05605.12 ORY42309.1 - 0.0041 17.4 0.4 0.0094 16.2 0.4 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding ADK_lid PF05191.14 ORY42309.1 - 0.0094 15.9 0.7 2.9 8.0 0.1 3.0 3 0 0 3 3 3 1 Adenylate kinase, active site lid zf-C2H2_12 PF18658.1 ORY42309.1 - 0.016 14.7 0.8 0.016 14.7 0.8 2.0 1 1 1 2 2 2 0 Zinc-finger C2H2-type zf-C2H2_2 PF12756.7 ORY42309.1 - 0.027 14.8 1.6 3.9 7.9 0.1 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn-ribbon_8 PF09723.10 ORY42309.1 - 0.029 14.5 4.9 2.9 8.1 0.2 2.8 3 0 0 3 3 3 0 Zinc ribbon domain FOXP-CC PF16159.5 ORY42309.1 - 0.054 14.1 0.4 0.13 12.9 0.4 1.6 1 0 0 1 1 1 0 FOXP coiled-coil domain DUF2256 PF10013.9 ORY42309.1 - 0.1 12.8 0.9 5.8 7.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zinc_ribbon_5 PF13719.6 ORY42309.1 - 0.41 10.4 3.1 3.3 7.6 0.9 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-C2H2_11 PF16622.5 ORY42309.1 - 0.95 9.3 8.0 0.97 9.2 0.3 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 ORY42310.1 - 1.1e-05 25.3 0.1 1.1e-05 25.3 0.1 1.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY42310.1 - 4.4e-05 23.7 0.7 0.00048 20.4 0.2 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 ORY42310.1 - 4.6e-05 23.6 0.1 4.6e-05 23.6 0.1 2.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 ORY42310.1 - 7.1e-05 22.6 1.1 0.00013 21.8 1.1 1.5 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 ORY42310.1 - 0.00023 21.7 0.1 0.00023 21.7 0.1 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.7 ORY42310.1 - 0.0026 18.1 0.2 0.0051 17.2 0.0 1.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-LSD1 PF06943.12 ORY42310.1 - 0.024 14.5 0.1 0.042 13.7 0.1 1.4 1 0 0 1 1 1 0 LSD1 zinc finger HET PF06985.11 ORY42312.1 - 1.8e-09 38.1 0.4 3.4e-09 37.2 0.4 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AAA_10 PF12846.7 ORY42313.1 - 0.03 13.3 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain TrwB_AAD_bind PF10412.9 ORY42313.1 - 0.033 13.1 0.0 0.058 12.3 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain zf-C2H2_4 PF13894.6 ORY42314.1 - 1.4e-07 31.7 5.1 0.01 16.6 0.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY42314.1 - 8.1e-07 29.2 6.0 0.005 17.2 0.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type TFIIA PF03153.13 ORY42314.1 - 5e-05 23.5 19.5 5e-05 23.5 19.5 3.0 1 1 1 3 3 3 1 Transcription factor IIA, alpha/beta subunit zf-H2C2_2 PF13465.6 ORY42314.1 - 0.0005 20.4 1.1 0.77 10.3 0.0 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY42314.1 - 0.0022 18.2 0.1 2.6 8.4 0.3 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY42314.1 - 0.0059 16.6 0.8 2 8.5 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zinc_ribbon_5 PF13719.6 ORY42314.1 - 0.096 12.5 0.3 0.26 11.1 0.3 1.7 1 0 0 1 1 1 0 zinc-ribbon domain Zn_ribbon_recom PF13408.6 ORY42314.1 - 0.12 12.9 3.3 0.67 10.5 1.1 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Zn-ribbon_8 PF09723.10 ORY42314.1 - 0.14 12.3 2.3 0.64 10.2 1.6 2.3 1 1 1 2 2 2 0 Zinc ribbon domain zf-LYAR PF08790.11 ORY42314.1 - 0.27 11.2 1.0 7.1 6.6 0.0 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger DnaGprimase_HBD PF16730.5 ORY42314.1 - 3.6 7.7 9.4 0.7 10.0 2.1 2.6 3 0 0 3 3 3 0 DnaG-primase C-terminal, helicase-binding domain CIAPIN1 PF05093.13 ORY42315.1 - 9.2e-26 90.3 10.6 1e-25 90.1 8.5 2.3 1 1 1 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis BSP_II PF05432.11 ORY42315.1 - 0.9 9.2 3.9 1.2 8.8 3.9 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CTP_transf_like PF01467.26 ORY42316.1 - 2.2e-23 83.0 0.0 3.7e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like ETC_C1_NDUFA5 PF04716.14 ORY42317.1 - 0.0014 18.4 0.2 0.0014 18.4 0.2 2.5 3 0 0 3 3 3 1 ETC complex I subunit conserved region GAPT PF11770.8 ORY42317.1 - 0.16 11.8 2.2 0.3 11.0 2.2 1.4 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Big_2 PF02368.18 ORY42317.1 - 0.26 11.2 4.6 0.26 11.2 0.6 2.5 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) DUF4078 PF13300.6 ORY42317.1 - 0.71 10.2 5.7 1.3 9.4 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4078) bZIP_2 PF07716.15 ORY42318.1 - 0.026 14.6 11.8 0.73 10.0 7.4 2.2 2 0 0 2 2 2 0 Basic region leucine zipper NP1-WLL PF11733.8 ORY42318.1 - 0.16 11.8 0.6 0.32 10.7 0.6 1.5 1 1 1 2 2 2 0 Non-capsid protein NP1 bZIP_1 PF00170.21 ORY42318.1 - 1.5 9.0 15.5 13 6.0 15.5 2.0 1 1 0 1 1 1 0 bZIP transcription factor SUIM_assoc PF16619.5 ORY42319.1 - 0.062 13.4 2.9 0.16 12.0 0.2 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 SANT_DAMP1_like PF16282.5 ORY42320.1 - 3.7e-27 94.3 2.4 4.5e-27 94.0 0.5 2.1 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 ORY42320.1 - 1.2e-08 35.0 0.1 4.5e-08 33.2 0.1 1.9 1 1 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-bind_6 PF13921.6 ORY42320.1 - 0.0052 17.0 0.1 0.021 15.0 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 ORY42320.1 - 0.052 13.8 0.0 0.052 13.8 0.0 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 ORY42320.1 - 0.44 10.5 0.1 0.44 10.5 0.1 2.5 3 0 0 3 3 3 0 Myb DNA-binding like 4HBT_2 PF13279.6 ORY42321.1 - 6e-08 33.2 0.0 9.3e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF382 PF04037.13 ORY42321.1 - 0.026 14.7 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF382) 4HBT PF03061.22 ORY42321.1 - 0.093 13.1 0.0 0.18 12.2 0.0 1.5 1 1 0 1 1 1 0 Thioesterase superfamily 4HBT_2 PF13279.6 ORY42322.1 - 5.6e-15 55.9 0.1 6.5e-15 55.7 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 ORY42322.1 - 4.5e-07 30.1 0.1 7.1e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 ORY42322.1 - 4.4e-05 22.9 0.0 0.22 10.8 0.0 2.0 2 0 0 2 2 2 2 Acyl-ACP thioesterase DUF3642 PF12182.8 ORY42324.1 - 0.056 13.7 1.8 50 4.3 0.0 4.8 6 0 0 6 6 6 0 Bacterial lipoprotein HSP70 PF00012.20 ORY42325.1 - 8.2e-262 869.7 9.2 9.3e-262 869.6 9.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY42325.1 - 2.6e-16 59.3 0.1 3.6e-15 55.6 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 ORY42325.1 - 0.0017 18.1 0.0 0.004 16.9 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 ORY42325.1 - 0.0062 15.8 0.1 0.014 14.7 0.1 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 ORY42325.1 - 0.023 14.2 0.0 4.6 6.7 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.11 ORY42325.1 - 0.074 12.3 1.2 0.39 9.9 0.0 2.1 2 0 0 2 2 2 0 StbA protein Vta1 PF04652.16 ORY42325.1 - 0.35 10.8 3.7 0.78 9.7 3.7 1.6 1 0 0 1 1 1 0 Vta1 like Ribosomal_L14 PF00238.19 ORY42326.1 - 6.9e-35 119.8 0.0 8.9e-35 119.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e zinc_ribbon_6 PF14599.6 ORY42327.1 - 2.9e-22 78.4 6.0 2.9e-22 78.4 6.0 4.9 4 1 1 5 5 5 1 Zinc-ribbon zf-CHY PF05495.12 ORY42327.1 - 1.7e-19 70.1 23.5 1.7e-19 70.1 23.5 3.8 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 ORY42327.1 - 2.5e-08 34.1 10.8 2.5e-08 34.1 10.8 5.4 5 1 0 5 5 5 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORY42327.1 - 0.0001 22.0 8.4 0.0001 22.0 8.4 5.6 3 2 3 6 6 6 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY42327.1 - 0.00025 20.8 12.7 0.00025 20.8 12.7 5.4 6 2 2 8 8 8 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY42327.1 - 0.0033 17.1 6.4 0.0033 17.1 6.4 4.1 5 0 0 5 5 5 1 RING-like zinc finger AF-4 PF05110.13 ORY42328.1 - 0.019 13.1 6.8 0.018 13.1 6.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein INO80_Ies4 PF08193.11 ORY42328.1 - 0.02 14.9 2.3 0.023 14.7 2.3 1.1 1 0 0 1 1 1 0 INO80 complex subunit Ies4 HSP20 PF00011.21 ORY42331.1 - 1.5e-12 47.5 0.1 2.1e-12 47.1 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORY42331.1 - 9.2e-07 28.3 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Alkyl_sulf_C PF14864.6 ORY42331.1 - 0.046 14.0 0.0 0.11 12.7 0.0 1.7 1 1 1 2 2 2 0 Alkyl sulfatase C-terminal zf-CCCH_2 PF14608.6 ORY42334.1 - 4.4e-07 30.1 38.8 0.00016 22.0 10.2 3.4 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger Zip PF02535.22 ORY42334.1 - 4.2 6.5 9.3 9.1 5.4 9.3 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIA PF03153.13 ORY42334.1 - 5.1 7.0 46.9 6.6 6.6 5.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Glyco_trans_1_2 PF13524.6 ORY42335.1 - 0.00057 20.2 0.8 0.0031 17.9 0.1 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 DNA_pol_A_exo1 PF01612.20 ORY42336.1 - 2e-08 34.2 0.0 6.5e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 3'-5' exonuclease Glyco_trans_1_2 PF13524.6 ORY42337.1 - 0.00052 20.3 0.0 0.0012 19.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Astro_capsid_p PF12226.8 ORY42338.1 - 1.9 7.6 9.9 6.5 5.8 9.9 1.9 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF572 PF04502.13 ORY42338.1 - 2.2 7.8 21.4 3.8 7.1 21.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-RING_4 PF14570.6 ORY42340.1 - 1e-21 76.5 13.1 1e-21 76.5 13.1 2.1 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 ORY42340.1 - 8.6e-07 28.7 8.6 8.6e-07 28.7 8.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 ORY42340.1 - 1.7e-06 27.8 0.4 1.7e-05 24.5 0.4 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Prok-RING_4 PF14447.6 ORY42340.1 - 4.8e-05 23.1 13.7 0.0029 17.4 5.2 3.2 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 ORY42340.1 - 6.2e-05 23.2 10.7 6.2e-05 23.2 10.7 2.1 2 0 0 2 2 2 1 Ring finger domain zf-UDP PF14569.6 ORY42340.1 - 0.00038 20.5 4.4 0.00038 20.5 4.4 2.2 2 0 0 2 2 2 1 Zinc-binding RING-finger Baculo_IE-1 PF05290.11 ORY42340.1 - 0.0025 17.8 5.4 0.0025 17.8 5.4 2.1 2 0 0 2 2 2 1 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.12 ORY42340.1 - 0.0093 15.4 2.5 0.014 14.7 2.5 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger DUF1154 PF06631.11 ORY42340.1 - 0.089 12.8 0.3 0.19 11.8 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) NPDC1 PF06809.11 ORY42340.1 - 0.15 11.1 0.5 0.24 10.4 0.5 1.2 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) zf-C3HC4_2 PF13923.6 ORY42340.1 - 0.26 11.2 20.5 0.064 13.1 11.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY42340.1 - 0.68 9.8 19.9 0.2 11.5 10.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY42340.1 - 1 9.4 18.2 0.86 9.7 5.9 3.3 3 0 0 3 3 3 0 RING-type zinc-finger zf-RING_10 PF16685.5 ORY42340.1 - 2.2 8.5 12.1 4.7 7.4 5.3 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 DUF4451 PF14616.6 ORY42340.1 - 2.5 8.3 8.2 3.9 7.7 1.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4451) Spc7_N PF15402.6 ORY42340.1 - 6.5 4.9 5.3 9.2 4.4 5.3 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 zf-RING_5 PF14634.6 ORY42340.1 - 7.7 6.6 17.8 4.3 7.4 9.2 2.6 2 0 0 2 2 2 0 zinc-RING finger domain SNF2_N PF00176.23 ORY42341.1 - 1.9e-67 227.5 0.8 1.9e-67 227.5 0.8 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY42341.1 - 1.1e-16 61.1 0.0 4.1e-16 59.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY42341.1 - 0.0018 18.1 0.1 0.012 15.4 0.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 ORY42341.1 - 0.031 13.5 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Csd3_N PF18059.1 ORY42341.1 - 0.034 14.7 0.1 4.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Csd3 N-terminal Glyco_hydro_46 PF01374.18 ORY42341.1 - 0.083 12.5 0.0 8 6.0 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 46 Pkinase PF00069.25 ORY42342.1 - 1.5e-70 237.6 0.0 1.8e-70 237.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY42342.1 - 1.8e-37 129.1 0.0 2.5e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY42342.1 - 0.0035 16.7 0.0 0.0062 15.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY42342.1 - 0.34 9.8 8.1 0.044 12.7 0.3 2.2 2 0 0 2 2 2 0 Haspin like kinase domain Voltage_CLC PF00654.20 ORY42343.1 - 2.3e-51 175.1 27.2 4.9e-39 134.6 12.5 3.0 3 0 0 3 3 3 3 Voltage gated chloride channel CBS PF00571.28 ORY42343.1 - 0.00032 21.1 0.1 0.0013 19.2 0.0 2.0 2 0 0 2 2 2 1 CBS domain Voltage_CLC PF00654.20 ORY42344.1 - 3.2e-72 243.7 24.4 3.2e-72 243.7 24.4 2.1 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 ORY42344.1 - 5.5e-08 33.1 0.2 1.3e-05 25.5 0.1 2.5 2 0 0 2 2 2 2 CBS domain UEV PF05743.13 ORY42345.1 - 1.1e-35 122.1 0.0 1.5e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 UEV domain Pkinase PF00069.25 ORY42347.1 - 2.9e-58 197.3 0.0 4.2e-58 196.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY42347.1 - 2.7e-15 56.4 0.1 3.1e-14 52.9 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY42347.1 - 4.8e-08 33.2 0.0 3.3e-07 30.5 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY42347.1 - 0.0094 14.8 0.0 0.02 13.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 ORY42347.1 - 0.018 14.6 1.2 0.023 14.3 0.0 1.7 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kinase-like PF14531.6 ORY42347.1 - 0.037 13.3 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 ORY42347.1 - 0.067 12.8 0.2 0.13 11.9 0.2 1.4 1 1 0 1 1 1 0 RIO1 family Kdo PF06293.14 ORY42347.1 - 0.073 12.4 0.3 0.15 11.4 0.2 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_C15 PF01470.17 ORY42349.1 - 2.8e-06 27.6 0.0 0.15 12.2 0.0 2.8 1 1 2 3 3 3 2 Pyroglutamyl peptidase Fumble PF03630.14 ORY42350.1 - 1.3e-115 386.1 0.0 1.9e-115 385.6 0.0 1.2 1 0 0 1 1 1 1 Fumble DUF89 PF01937.19 ORY42350.1 - 6.1e-39 134.0 0.1 8.3e-39 133.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF89 LupA PF18242.1 ORY42350.1 - 0.0026 17.4 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 Legionella ubiquitin-specific protease A domain AAA_16 PF13191.6 ORY42352.1 - 5e-06 27.0 2.5 1.1e-05 26.0 0.9 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY42352.1 - 0.0011 19.3 0.1 3.3 8.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.6 ORY42352.1 - 0.0092 16.0 0.0 0.8 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ORY42352.1 - 0.026 14.9 0.0 5.9 7.3 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ORY42352.1 - 0.09 12.9 0.3 0.34 11.1 0.0 2.2 2 1 0 2 2 2 0 AAA domain HSP20 PF00011.21 ORY42353.1 - 3.7e-10 39.9 0.8 5.5e-10 39.3 0.8 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORY42353.1 - 0.0018 17.8 0.2 0.0035 16.9 0.2 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Orthoreo_P10 PF07204.11 ORY42354.1 - 0.0067 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 Mid2 PF04478.12 ORY42354.1 - 0.0098 15.7 0.2 0.026 14.4 0.2 1.7 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor Borealin PF10512.9 ORY42354.1 - 0.01 15.8 0.5 0.036 14.0 0.5 1.9 1 0 0 1 1 1 0 Cell division cycle-associated protein 8 DUF4733 PF15878.5 ORY42354.1 - 0.13 12.7 0.2 0.48 10.9 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4733) DUF3172 PF11371.8 ORY42356.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) Acetyltransf_3 PF13302.7 ORY42357.1 - 9.6e-14 52.2 0.0 1.5e-13 51.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY42357.1 - 3.9e-07 30.3 0.0 5.1e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family SAM_PNT PF02198.16 ORY42358.1 - 1.3e-05 25.1 0.0 2.7e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_1 PF00536.30 ORY42358.1 - 0.01 16.3 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 ORY42358.1 - 0.12 12.6 0.2 0.72 10.1 0.2 2.1 2 0 0 2 2 2 0 Ste50p, sterile alpha motif Rick_17kDa_Anti PF05433.15 ORY42358.1 - 0.19 11.6 9.1 0.39 10.6 9.1 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain WD40 PF00400.32 ORY42359.1 - 1.6e-17 63.5 12.7 0.0021 18.9 0.3 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY42359.1 - 9.3e-09 35.5 0.2 0.00025 21.3 0.0 4.6 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain SL4P PF17618.2 ORY42360.1 - 0.093 12.8 0.4 0.89 9.7 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized Strongylid L4 protein Mito_carr PF00153.27 ORY42361.1 - 2.2e-66 219.9 5.1 6.3e-22 77.3 0.1 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein Metallophos PF00149.28 ORY42362.1 - 6e-40 137.9 0.1 8.3e-40 137.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORY42362.1 - 1.2e-22 80.1 0.5 2.4e-22 79.1 0.2 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Peptidase_M13_N PF05649.13 ORY42363.1 - 5.8e-59 200.7 0.4 4.6e-58 197.7 0.4 2.4 1 1 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 ORY42363.1 - 3.9e-48 163.8 3.3 3.4e-40 137.8 0.0 2.6 2 0 0 2 2 2 2 Peptidase family M13 ThrE PF06738.12 ORY42364.1 - 1.4e-22 80.2 10.4 2.7e-15 56.4 13.9 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter RRN3 PF05327.11 ORY42364.1 - 0.031 12.9 0.5 0.04 12.5 0.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Med26 PF08711.11 ORY42364.1 - 0.047 13.7 0.1 4.6 7.3 0.0 2.7 2 0 0 2 2 2 0 TFIIS helical bundle-like domain BNIP2 PF12496.8 ORY42364.1 - 0.23 11.9 3.5 0.4 11.1 3.5 1.3 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 MNHE PF01899.16 ORY42364.1 - 0.23 11.2 2.3 0.41 10.4 2.3 1.4 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit ThrE_2 PF12821.7 ORY42364.1 - 3.3 7.8 9.1 6.1 7.0 8.9 1.5 1 1 0 1 1 1 0 Threonine/Serine exporter, ThrE ThrE PF06738.12 ORY42365.1 - 4.4e-39 134.3 23.7 1.3e-30 106.5 5.6 3.2 3 0 0 3 3 3 3 Putative threonine/serine exporter ThrE_2 PF12821.7 ORY42365.1 - 4e-07 30.2 25.9 3.7e-06 27.1 11.2 2.3 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE RNA_polI_A14 PF08203.11 ORY42365.1 - 0.096 13.4 1.5 0.87 10.4 0.4 2.5 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 ThrE PF06738.12 ORY42366.1 - 3.3e-39 134.7 23.5 1.4e-30 106.4 6.4 3.1 3 0 0 3 3 3 3 Putative threonine/serine exporter ThrE_2 PF12821.7 ORY42366.1 - 4.5e-06 26.8 23.6 8e-06 26.0 7.9 2.3 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE PfkB PF00294.24 ORY42367.1 - 1.7e-44 152.4 0.0 2.2e-44 152.0 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase PfkB PF00294.24 ORY42368.1 - 1.1e-57 195.6 0.4 1.3e-57 195.4 0.4 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase ABC1 PF03109.16 ORY42369.1 - 6.6e-22 77.9 0.0 1.4e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 ABC1 family GCS PF03074.16 ORY42370.1 - 7.1e-143 476.4 0.0 2e-95 320.2 0.0 2.1 1 1 1 2 2 2 2 Glutamate-cysteine ligase DUF1331 PF07048.11 ORY42370.1 - 0.085 12.5 0.0 0.55 9.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1331) Kinesin PF00225.23 ORY42371.1 - 7.8e-06 25.0 0.0 1.7e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Pol_alpha_B_N PF08418.10 ORY42371.1 - 0.43 10.5 12.3 0.61 10.0 12.3 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Kinesin PF00225.23 ORY42372.1 - 6.3e-100 334.3 0.5 7.6e-100 334.1 0.5 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY42372.1 - 1.7e-18 67.0 1.2 1.2e-17 64.2 0.1 2.8 2 1 0 2 2 2 1 Microtubule binding Bac_DnaA PF00308.18 ORY42372.1 - 0.025 14.4 0.0 0.066 13.0 0.0 1.6 2 0 0 2 2 2 0 Bacterial dnaA protein Kinesin PF00225.23 ORY42373.1 - 3.1e-65 220.3 0.4 1.6e-64 217.9 0.4 1.8 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY42373.1 - 7.3e-22 77.9 0.5 6.9e-21 74.8 0.5 2.3 1 1 0 1 1 1 1 Microtubule binding ABC_tran PF00005.27 ORY42374.1 - 2.4e-14 54.0 0.9 1.2e-13 51.7 0.2 2.3 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 ORY42374.1 - 0.0022 17.7 0.1 0.0039 16.9 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Dynamin_N PF00350.23 ORY42374.1 - 0.0027 17.8 0.1 0.0046 17.0 0.0 1.5 2 0 0 2 2 2 1 Dynamin family AAA_21 PF13304.6 ORY42374.1 - 0.0034 17.2 0.1 0.0068 16.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 ORY42374.1 - 0.0043 17.1 0.0 0.0076 16.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 ORY42374.1 - 0.011 16.3 0.8 0.011 16.3 0.8 2.1 1 1 1 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 ORY42374.1 - 0.012 15.5 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 ORY42374.1 - 0.031 14.0 0.1 0.047 13.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain Chrome_Resist PF09828.9 ORY42374.1 - 0.066 13.7 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Chromate resistance exported protein AAA_27 PF13514.6 ORY42374.1 - 0.12 11.9 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran_Xtn PF12848.7 ORY42374.1 - 0.15 12.1 1.2 0.24 11.5 1.2 1.3 1 0 0 1 1 1 0 ABC transporter RhoGAP PF00620.27 ORY42378.1 - 8.2e-21 74.4 0.0 9.9e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain XRCC4 PF06632.12 ORY42379.1 - 2.1e-08 33.4 0.1 2.7e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Ribosomal_S10 PF00338.22 ORY42379.1 - 0.036 14.3 0.8 0.076 13.2 0.7 1.6 1 1 0 1 1 1 0 Ribosomal protein S10p/S20e HTH_26 PF13443.6 ORY42379.1 - 0.25 11.8 1.3 7.6 7.1 0.1 2.2 1 1 1 2 2 2 0 Cro/C1-type HTH DNA-binding domain RRM_1 PF00076.22 ORY42381.1 - 3.1e-06 26.9 0.1 5.9e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF5107 PF17128.4 ORY42381.1 - 0.046 12.9 0.0 0.99 8.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5107) DUF2937 PF11157.8 ORY42382.1 - 0.072 12.8 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) zf-C3HC4_2 PF13923.6 ORY42384.1 - 2.5e-08 33.6 14.1 4e-08 33.0 14.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY42384.1 - 7.3e-08 32.6 13.2 1.2e-07 32.0 13.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORY42384.1 - 1.2e-07 31.5 7.4 1.7e-07 31.0 7.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY42384.1 - 3.7e-07 29.9 12.6 5.7e-07 29.3 12.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY42384.1 - 4.2e-06 26.7 8.7 4.2e-06 26.7 8.7 1.8 1 1 1 2 2 2 1 RING-type zinc-finger PWI PF01480.17 ORY42384.1 - 5.4e-06 26.6 0.0 1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 PWI domain zf-rbx1 PF12678.7 ORY42384.1 - 6.4e-05 23.2 11.1 0.00016 21.9 11.1 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 ORY42384.1 - 0.00018 21.4 10.0 0.00032 20.6 10.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORY42384.1 - 0.00093 19.3 14.6 0.0016 18.5 14.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ORY42384.1 - 0.0073 16.1 14.1 0.067 13.1 13.7 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 ORY42384.1 - 0.019 14.8 6.9 0.043 13.7 6.9 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 ORY42384.1 - 0.42 10.4 7.5 0.97 9.3 7.2 1.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 ORY42384.1 - 0.7 10.0 5.8 1.7 8.7 5.8 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 ORY42384.1 - 2.3 7.9 10.7 8.3 6.2 10.7 1.9 1 1 0 1 1 1 0 P-11 zinc finger RecR PF02132.15 ORY42384.1 - 8.9 6.0 7.0 1.9 8.1 0.4 2.3 2 0 0 2 2 2 0 RecR protein S1-P1_nuclease PF02265.16 ORY42386.1 - 2.1e-18 67.0 0.0 1.2e-10 41.7 0.0 2.3 1 1 1 2 2 2 2 S1/P1 Nuclease Lipase_3 PF01764.25 ORY42387.1 - 1.1e-33 116.1 0.0 1.5e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 ORY42387.1 - 0.012 15.1 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Esterase PF00756.20 ORY42387.1 - 0.057 13.0 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_6 PF12697.7 ORY42387.1 - 0.064 13.8 3.7 0.14 12.7 3.7 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.8 ORY42387.1 - 0.067 12.7 0.0 0.37 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 ORY42387.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Jiraiya PF15038.6 ORY42388.1 - 0.0097 15.3 1.7 0.79 9.1 0.3 2.6 2 0 0 2 2 2 2 Jiraiya DUF4982 PF16355.5 ORY42389.1 - 0.0085 16.0 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) DHHC PF01529.20 ORY42390.1 - 3.5 7.7 15.6 1.1 9.4 2.1 3.5 4 0 0 4 4 4 0 DHHC palmitoyltransferase DUF4282 PF14110.6 ORY42390.1 - 8.9 7.1 23.8 1.3 9.9 0.1 4.0 4 1 0 4 4 4 0 Domain of unknown function (DUF4282) Tetraspanin PF00335.20 ORY42390.1 - 9.4 5.9 23.6 0.1 12.3 11.5 3.2 3 2 0 3 3 3 0 Tetraspanin family Tetraspanin PF00335.20 ORY42391.1 - 0.11 12.2 12.4 0.48 10.1 8.4 2.5 2 0 0 2 2 2 0 Tetraspanin family DUF3953 PF13129.6 ORY42391.1 - 7.7 6.4 15.4 1.1 9.0 0.7 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3953) hDGE_amylase PF14701.6 ORY42392.1 - 6.7e-155 516.5 0.5 8.5e-82 275.6 0.0 2.2 1 1 1 2 2 2 2 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 ORY42392.1 - 1.6e-64 218.3 0.0 3.1e-64 217.3 0.0 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 ORY42392.1 - 1e-52 179.3 0.0 1.7e-51 175.3 0.0 2.4 1 1 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 ORY42392.1 - 9.3e-10 38.5 0.0 2.1e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 ORY42392.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 2 0 0 2 2 2 0 Alpha amylase, catalytic domain PH PF00169.29 ORY42393.1 - 4.4e-05 23.9 0.0 9.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 PH domain MMM1 PF10296.9 ORY42393.1 - 0.00077 18.6 0.1 0.0043 16.2 0.0 2.0 1 1 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 TamB PF04357.13 ORY42393.1 - 0.14 11.4 1.3 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 TamB, inner membrane protein subunit of TAM complex SPATA1_C PF15743.5 ORY42454.1 - 0.0026 17.8 4.0 0.0039 17.3 4.0 1.2 1 0 0 1 1 1 1 Spermatogenesis-associated C-terminus DUF3015 PF11220.8 ORY42454.1 - 0.014 15.2 1.2 0.033 14.1 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) FlaC_arch PF05377.11 ORY42454.1 - 0.44 11.0 2.2 2.7 8.5 0.1 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4355 PF14265.6 ORY42454.1 - 0.96 9.7 9.3 1.8 8.8 9.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) TMPIT PF07851.13 ORY42454.1 - 3.5 6.8 6.1 5.5 6.2 6.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein NACHT PF05729.12 ORY42455.1 - 5.7e-08 32.8 0.0 1.3e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Talin_middle PF09141.10 ORY42455.1 - 0.00036 20.6 1.2 0.13 12.3 0.3 2.8 1 1 0 2 2 2 2 Talin, middle domain DUF4404 PF14357.6 ORY42455.1 - 0.0099 16.5 1.1 27 5.5 0.0 4.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) AAA_16 PF13191.6 ORY42455.1 - 0.016 15.6 0.0 0.051 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain FANCI_S3 PF14677.6 ORY42455.1 - 0.027 14.2 0.3 0.17 11.6 0.1 2.4 1 1 1 2 2 2 0 FANCI solenoid 3 RNA_helicase PF00910.22 ORY42455.1 - 0.054 13.9 0.1 3.7 8.0 0.0 3.3 3 0 0 3 3 3 0 RNA helicase XPC-binding PF09280.11 ORY42455.1 - 0.066 12.9 0.6 0.3 10.9 0.3 2.3 2 0 0 2 2 2 0 XPC-binding domain Thioredoxin_6 PF13848.6 ORY42455.1 - 3.1 7.7 7.0 9.6 6.1 0.1 3.1 4 0 0 4 4 4 0 Thioredoxin-like domain CAP_N PF01213.19 ORY42456.1 - 0.0042 16.6 0.2 0.0056 16.2 0.2 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Pkip-1 PF06878.11 ORY42456.1 - 0.03 14.4 2.6 0.047 13.8 2.6 1.3 1 0 0 1 1 1 0 Pkip-1 protein zf-ZPR1 PF03367.13 ORY42456.1 - 0.089 12.6 1.9 0.48 10.3 1.9 2.1 1 1 0 1 1 1 0 ZPR1 zinc-finger domain Nnf1 PF03980.14 ORY42456.1 - 0.33 11.3 3.2 0.58 10.5 3.2 1.3 1 0 0 1 1 1 0 Nnf1 Bro-N PF02498.17 ORY42458.1 - 3.2e-05 24.5 0.2 0.0046 17.6 0.0 2.7 2 1 1 3 3 3 2 BRO family, N-terminal domain KELK PF15796.5 ORY42458.1 - 0.017 15.5 7.2 0.017 15.5 7.2 1.6 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF1256 PF06866.11 ORY42458.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) zf-C2H2 PF00096.26 ORY42459.1 - 1.7e-07 31.3 11.3 0.00024 21.4 3.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY42459.1 - 1.4e-06 28.6 11.2 6e-05 23.6 2.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY42459.1 - 0.00014 21.8 4.7 0.0013 18.7 0.4 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY42459.1 - 0.017 15.4 6.0 0.072 13.4 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 ORY42459.1 - 0.022 14.4 5.1 0.025 14.2 1.2 2.3 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Lar_restr_allev PF14354.6 ORY42459.1 - 0.026 14.9 0.3 0.043 14.2 0.3 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar OrsD PF12013.8 ORY42459.1 - 0.12 12.8 2.3 1.6 9.2 0.4 2.4 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Actin_micro PF17003.5 ORY42459.1 - 0.13 11.4 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative actin-like family zf-Di19 PF05605.12 ORY42459.1 - 0.14 12.4 8.9 14 6.1 6.7 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 ORY42459.1 - 0.15 12.6 9.3 2.5 8.7 0.9 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-HYPF PF07503.12 ORY42459.1 - 0.16 11.8 2.4 0.35 10.7 2.4 1.5 1 0 0 1 1 1 0 HypF finger zf-CSL PF05207.13 ORY42459.1 - 0.18 11.6 0.4 0.31 10.8 0.4 1.3 1 0 0 1 1 1 0 CSL zinc finger DUF2256 PF10013.9 ORY42459.1 - 0.36 11.0 1.5 15 5.8 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_9 PF16293.5 ORY42459.1 - 0.54 10.2 2.0 0.82 9.6 0.1 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) DDE_1 PF03184.19 ORY42460.1 - 0.0024 17.5 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease CENP-T_C PF15511.6 ORY42460.1 - 0.066 13.3 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold PAN_4 PF14295.6 ORY42461.1 - 0.00011 22.0 1.9 0.00011 22.0 1.9 1.8 2 0 0 2 2 2 1 PAN domain PAN_2 PF08276.11 ORY42461.1 - 0.051 13.7 1.3 0.051 13.7 1.3 1.6 1 1 0 1 1 1 0 PAN-like domain PAN_1 PF00024.26 ORY42461.1 - 0.051 13.5 1.9 0.066 13.2 0.6 1.8 1 1 1 2 2 2 0 PAN domain LON_substr_bdg PF02190.16 ORY42462.1 - 0.11 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 ATP-dependent protease La (LON) substrate-binding domain Glyco_hydro_20 PF00728.22 ORY42464.1 - 7.7e-72 242.6 0.0 9.9e-72 242.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY42464.1 - 3.9e-13 50.2 0.6 1.2e-11 45.5 0.4 2.7 2 1 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY42464.1 - 3.1e-09 37.7 0.4 1.1e-08 35.9 0.3 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Big_7 PF17957.1 ORY42464.1 - 0.15 12.8 3.9 0.57 11.0 3.6 2.3 1 1 0 1 1 1 0 Bacterial Ig domain Glyco_hydro_20 PF00728.22 ORY42465.1 - 3.7e-71 240.4 0.0 4.7e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY42465.1 - 7.7e-11 42.8 2.0 9.6e-10 39.3 1.3 2.7 2 1 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY42465.1 - 5.9e-09 36.8 0.1 2.4e-08 34.8 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 RRN9 PF10680.9 ORY42466.1 - 0.11 12.8 0.5 3 8.2 0.5 2.1 1 1 0 1 1 1 0 RNA polymerase I specific transcription initiation factor D5_N PF08706.11 ORY42467.1 - 1.5e-09 38.3 0.5 2.9e-09 37.3 0.5 1.4 1 0 0 1 1 1 1 D5 N terminal like RTA1 PF04479.13 ORY42468.1 - 3.8e-58 196.5 12.9 8.2e-48 162.7 5.8 2.2 1 1 1 2 2 2 2 RTA1 like protein Ses_B PF17046.5 ORY42470.1 - 0.24 11.4 0.8 0.41 10.6 0.8 1.4 1 0 0 1 1 1 0 SesB domain on fungal death-pathway protein zf_C2H2_ZHX PF18387.1 ORY42475.1 - 0.021 14.5 1.1 0.035 13.7 1.1 1.3 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2 PF00096.26 ORY42475.1 - 0.058 13.9 1.1 0.058 13.9 1.1 1.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type OrsD PF12013.8 ORY42475.1 - 0.12 12.9 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D DUF2813 PF11398.8 ORY42475.1 - 0.15 11.3 0.3 0.29 10.3 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2813) Cluap1 PF10234.9 ORY42478.1 - 0.0058 16.1 0.1 0.0068 15.8 0.1 1.1 1 0 0 1 1 1 1 Clusterin-associated protein-1 WCCH PF03716.14 ORY42478.1 - 0.21 11.3 8.9 0.4 10.4 8.9 1.4 1 0 0 1 1 1 0 WCCH motif Glyco_hydro_20 PF00728.22 ORY42481.1 - 1.5e-71 241.7 0.0 2e-71 241.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY42481.1 - 3.9e-13 50.2 0.6 1.2e-11 45.5 0.4 2.7 2 1 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY42481.1 - 2.2e-09 38.2 0.4 1.1e-08 35.9 0.3 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Big_7 PF17957.1 ORY42481.1 - 0.15 12.8 3.9 0.57 11.0 3.6 2.3 1 1 0 1 1 1 0 Bacterial Ig domain Glyco_hydro_20 PF00728.22 ORY42482.1 - 3e-71 240.7 0.0 3.9e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY42482.1 - 1.2e-10 42.2 1.9 1.4e-09 38.7 1.3 2.7 2 1 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY42482.1 - 3.5e-09 37.5 0.1 2.1e-08 35.0 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 YojJ PF10372.9 ORY42483.1 - 0.028 14.5 1.7 0.028 14.5 1.7 2.5 3 1 1 4 4 4 0 Bacterial membrane-spanning protein N-terminus ApoO PF09769.9 ORY42483.1 - 0.092 12.7 1.6 0.11 12.4 0.2 2.0 2 0 0 2 2 2 0 Apolipoprotein O Flagellin_C PF00700.21 ORY42483.1 - 0.11 12.9 1.7 0.34 11.3 0.2 2.3 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region DUF4320 PF14208.6 ORY42483.1 - 9.6 6.3 13.5 4.6 7.3 4.3 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF4320) LRR_1 PF00560.33 ORY42484.1 - 0.14 12.8 0.7 37 5.4 0.3 3.7 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.7 ORY42484.1 - 0.21 12.1 6.9 1.3 9.6 0.8 2.6 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY42484.1 - 1.1 9.5 3.3 24 5.3 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich repeat HSP70 PF00012.20 ORY42485.1 - 5e-45 153.8 0.4 6.1e-45 153.5 0.4 1.1 1 0 0 1 1 1 1 Hsp70 protein DTC PF18102.1 ORY42485.1 - 3.2e-06 27.3 0.2 0.00022 21.3 0.1 3.3 3 1 0 3 3 3 1 Deltex C-terminal domain MreB_Mbl PF06723.13 ORY42485.1 - 8.1e-05 21.6 0.0 0.00013 20.9 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein PARP PF00644.20 ORY42486.1 - 1.2e-05 24.9 0.1 8.1e-05 22.3 0.1 2.2 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain zf-RanBP PF00641.18 ORY42486.1 - 0.0088 15.3 1.0 0.0088 15.3 1.0 1.9 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others DZR PF12773.7 ORY42486.1 - 0.13 12.4 0.6 0.26 11.3 0.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon RVP_2 PF08284.11 ORY42487.1 - 6.3e-05 22.8 0.1 6.4e-05 22.7 0.1 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 ORY42487.1 - 0.0011 19.6 0.0 0.0015 19.2 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 ORY42487.1 - 0.014 15.9 0.0 0.02 15.5 0.0 1.2 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 ORY42487.1 - 0.023 14.5 0.0 0.025 14.4 0.0 1.0 1 0 0 1 1 1 0 Aspartyl protease Retrotrans_gag PF03732.17 ORY42488.1 - 2e-05 24.8 0.3 5.2e-05 23.4 0.1 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4919 PF16266.5 ORY42488.1 - 0.035 14.0 0.1 0.076 13.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) DUF3524 PF12038.8 ORY42488.1 - 0.085 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3524) DDE_1 PF03184.19 ORY42490.1 - 0.17 11.5 0.2 11 5.7 0.0 2.3 1 1 0 2 2 2 0 DDE superfamily endonuclease Peptidase_C48 PF02902.19 ORY42491.1 - 0.00027 20.9 0.1 0.00066 19.6 0.0 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Histone PF00125.24 ORY42492.1 - 5.5e-05 23.5 2.4 0.00022 21.6 0.3 2.0 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 CsgE PF10627.9 ORY42497.1 - 0.041 14.1 0.1 0.044 14.0 0.1 1.0 1 0 0 1 1 1 0 Curli assembly protein CsgE CactinC_cactus PF09732.9 ORY42499.1 - 6.5e-60 200.6 8.9 1.2e-59 199.7 8.9 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 ORY42499.1 - 4.6e-58 196.2 2.1 4.6e-58 196.2 2.1 2.5 2 0 0 2 2 2 1 Conserved mid region of cactin SF3A2 PF16835.5 ORY42499.1 - 0.041 14.2 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) FliL PF03748.14 ORY42499.1 - 2 9.0 5.6 3.3 8.4 0.1 3.2 3 0 0 3 3 3 0 Flagellar basal body-associated protein FliL tRNA-synt_1b PF00579.25 ORY42500.1 - 2.6e-76 256.7 0.0 3.4e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 ORY42500.1 - 0.0012 18.5 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain SPOB_ab PF14682.6 ORY42500.1 - 0.088 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal TyrRSs_C PF16714.5 ORY42500.1 - 0.29 11.0 1.0 12 5.8 1.0 2.4 1 1 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain CBM_21 PF03370.13 ORY42501.1 - 1.2e-06 28.7 0.0 2.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 ORY42501.1 - 0.043 14.4 0.0 0.13 12.9 0.0 1.8 1 1 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) Haem_degrading PF03928.14 ORY42501.1 - 0.048 13.7 0.8 0.091 12.8 0.8 1.4 1 0 0 1 1 1 0 Haem-degrading Methyltransf_16 PF10294.9 ORY42502.1 - 1.5e-19 70.4 0.0 1.1e-18 67.6 0.0 2.1 1 1 0 1 1 1 1 Lysine methyltransferase DUF938 PF06080.12 ORY42502.1 - 0.004 16.9 0.0 0.0058 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF938) MTS PF05175.14 ORY42502.1 - 0.088 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Aminotran_1_2 PF00155.21 ORY42503.1 - 1.6e-32 113.1 0.0 2.1e-32 112.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Rubredoxin PF00301.20 ORY42504.1 - 0.04 13.9 0.0 0.093 12.8 0.0 1.5 1 0 0 1 1 1 0 Rubredoxin RVT_1 PF00078.27 ORY42506.1 - 5.6e-05 22.8 0.0 7.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA PF00004.29 ORY42507.1 - 8.7e-10 39.1 0.1 2.5e-05 24.7 0.0 2.5 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 ORY42507.1 - 0.0093 15.3 0.0 1 8.6 0.0 2.3 2 0 0 2 2 2 2 KaiC AAA_16 PF13191.6 ORY42507.1 - 0.088 13.2 0.0 0.37 11.2 0.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.12 ORY42507.1 - 0.12 12.1 0.0 0.66 9.7 0.0 2.1 2 1 2 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 ORY42507.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ORY42507.1 - 0.15 12.4 0.2 3.6 7.9 0.2 2.4 1 1 0 1 1 1 0 AAA domain RNAse_A_bac PF18431.1 ORY42508.1 - 0.015 16.3 0.0 0.036 15.0 0.0 1.6 1 1 0 1 1 1 0 Bacterial CdiA-CT RNAse A domain 7TM-7TMR_HD PF07698.11 ORY42508.1 - 0.92 9.2 5.5 0.31 10.8 1.3 2.0 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Aminotran_1_2 PF00155.21 ORY42510.1 - 1.4e-34 119.9 0.0 1.6e-34 119.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.21 ORY42511.1 - 2.8e-34 118.9 0.0 3.7e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II CRAL_TRIO PF00650.20 ORY42512.1 - 1.6e-24 86.5 0.0 2.1e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 ORY42512.1 - 1.9e-05 24.8 0.0 2.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain cobW PF02492.19 ORY42514.1 - 1.3e-50 171.5 0.7 1.8e-50 171.0 0.7 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 ORY42514.1 - 2.3e-09 37.0 0.1 5.4e-09 35.9 0.1 1.7 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain SRPRB PF09439.10 ORY42514.1 - 0.0061 16.0 1.5 0.051 13.0 0.1 2.5 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 ORY42514.1 - 0.01 16.3 0.1 0.026 14.9 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.14 ORY42514.1 - 0.015 15.2 0.6 0.061 13.2 0.6 2.0 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.17 ORY42514.1 - 0.016 15.0 0.2 0.034 13.9 0.2 1.5 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 ORY42514.1 - 0.016 15.1 0.2 2.3 8.1 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase Viral_helicase1 PF01443.18 ORY42514.1 - 0.021 14.6 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.6 ORY42514.1 - 0.023 14.9 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 ORY42514.1 - 0.029 14.3 1.2 0.19 11.7 0.2 2.2 2 0 0 2 2 2 0 NTPase MeaB PF03308.16 ORY42514.1 - 0.03 13.3 1.3 0.14 11.1 0.2 2.3 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 ORY42514.1 - 0.054 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 ORY42514.1 - 0.066 12.7 1.5 0.28 10.7 1.3 1.9 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain NACHT PF05729.12 ORY42514.1 - 0.069 13.1 0.3 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Epimerase PF01370.21 ORY42515.1 - 2.8e-17 63.0 0.1 6e-17 61.9 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY42515.1 - 4.3e-15 55.5 0.0 1e-14 54.2 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 ORY42515.1 - 1.5e-10 41.3 0.5 3.1e-10 40.3 0.5 1.6 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ORY42515.1 - 2.9e-09 36.5 0.0 2.1e-08 33.7 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 ORY42515.1 - 8e-09 35.3 0.5 2.4e-08 33.7 0.0 2.0 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 ORY42515.1 - 7.4e-07 29.0 1.0 9.5e-06 25.3 0.5 2.2 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 ORY42515.1 - 0.00016 20.9 0.0 0.00023 20.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 ORY42515.1 - 0.00088 18.8 1.0 0.0041 16.6 0.3 2.2 2 1 0 2 2 2 1 short chain dehydrogenase Ldh_1_N PF00056.23 ORY42515.1 - 0.028 14.5 0.1 0.058 13.5 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 ORY42515.1 - 0.11 12.0 0.5 0.29 10.6 0.5 1.7 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NEMO PF11577.8 ORY42516.1 - 0.00069 19.6 0.2 0.0015 18.5 0.2 1.5 1 0 0 1 1 1 1 NF-kappa-B essential modulator NEMO DivIC PF04977.15 ORY42516.1 - 0.00081 19.1 1.3 0.0015 18.2 0.4 1.7 2 0 0 2 2 2 1 Septum formation initiator HALZ PF02183.18 ORY42516.1 - 0.0027 17.9 0.5 0.0055 16.9 0.5 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_1 PF00170.21 ORY42516.1 - 0.0058 16.7 0.2 0.011 15.8 0.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor FlaC_arch PF05377.11 ORY42516.1 - 0.0069 16.7 1.6 0.017 15.5 0.2 2.0 2 0 0 2 2 2 1 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.9 ORY42516.1 - 0.0085 16.1 0.2 0.015 15.4 0.1 1.5 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4635 PF15466.6 ORY42516.1 - 0.011 15.3 0.2 0.016 14.7 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4635) ZapB PF06005.12 ORY42516.1 - 0.013 16.0 0.6 0.022 15.2 0.2 1.5 2 0 0 2 2 2 0 Cell division protein ZapB DivIVA PF05103.13 ORY42516.1 - 0.017 15.2 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 DivIVA protein Cnn_1N PF07989.11 ORY42516.1 - 0.017 15.3 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 KLRAQ PF10205.9 ORY42516.1 - 0.037 14.3 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein CLZ PF16526.5 ORY42516.1 - 0.049 14.0 0.1 0.29 11.5 0.1 1.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_2 PF07716.15 ORY42516.1 - 0.049 13.7 0.4 0.082 13.0 0.4 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Rho_Binding PF08912.11 ORY42516.1 - 0.052 14.4 0.6 0.097 13.5 0.2 1.6 2 0 0 2 2 2 0 Rho Binding GIT_CC PF16559.5 ORY42516.1 - 0.063 13.2 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor APC_N_CC PF16689.5 ORY42516.1 - 0.078 13.0 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain PI3K_P85_iSH2 PF16454.5 ORY42516.1 - 0.12 12.0 0.7 0.24 11.0 0.7 1.6 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SIKE PF05769.11 ORY42516.1 - 0.14 12.1 0.6 0.15 12.0 0.6 1.2 1 1 0 1 1 1 0 SIKE family E1_dh PF00676.20 ORY42516.1 - 0.18 10.7 0.1 0.35 9.8 0.0 1.5 1 1 1 2 2 2 0 Dehydrogenase E1 component TIR_2 PF13676.6 ORY42517.1 - 2.3e-36 125.0 0.0 1e-16 61.6 0.0 3.1 2 1 1 3 3 3 2 TIR domain TIR PF01582.20 ORY42517.1 - 1e-06 28.7 0.0 0.0014 18.5 0.0 2.5 2 0 0 2 2 2 2 TIR domain RIX1 PF08167.12 ORY42517.1 - 0.0028 17.4 0.7 0.0078 16.0 0.1 2.1 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Sugarporin_N PF11471.8 ORY42517.1 - 0.034 14.1 0.1 0.12 12.4 0.1 1.9 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Spidroin_N PF16763.5 ORY42517.1 - 0.075 13.0 0.1 0.38 10.8 0.1 2.2 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term Ribo_biogen_C PF04034.13 ORY42518.1 - 3.9e-45 152.7 0.0 5e-45 152.3 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 ORY42518.1 - 3.9e-14 52.2 0.2 6.6e-14 51.4 0.2 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Zip PF02535.22 ORY42518.1 - 0.1 11.8 1.1 0.13 11.4 1.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DNA_pol_phi PF04931.13 ORY42518.1 - 0.55 8.3 3.5 0.65 8.0 3.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi PPP4R2 PF09184.11 ORY42518.1 - 2.8 7.5 6.9 7.9 6.0 6.5 1.7 2 0 0 2 2 2 0 PPP4R2 Sua5_yciO_yrdC PF01300.18 ORY42519.1 - 2.8e-56 189.9 0.0 4.6e-56 189.1 0.0 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 ORY42519.1 - 3.9e-27 95.4 0.0 7.7e-27 94.5 0.0 1.5 2 0 0 2 2 2 1 Putative GTP-binding controlling metal-binding TIR_2 PF13676.6 ORY42520.1 - 2.2e-35 121.8 0.0 4.3e-17 62.8 0.0 3.0 3 0 0 3 3 3 2 TIR domain TIR PF01582.20 ORY42520.1 - 5.7e-07 29.5 0.0 0.0024 17.7 0.0 2.4 2 0 0 2 2 2 2 TIR domain CPDase PF07823.11 ORY42520.1 - 0.0071 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein TIR_2 PF13676.6 ORY42522.1 - 0.12 13.0 0.0 0.25 12.0 0.0 1.5 1 0 0 1 1 1 0 TIR domain JmjC PF02373.22 ORY42523.1 - 1.1e-13 51.5 0.0 2.4e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 ORY42523.1 - 0.046 13.4 0.1 0.35 10.5 0.1 2.4 1 1 0 1 1 1 0 Cupin-like domain ELM2 PF01448.24 ORY42523.1 - 0.16 12.7 0.4 9.7 7.0 0.0 2.6 2 0 0 2 2 2 0 ELM2 domain ING PF12998.7 ORY42524.1 - 2.8e-11 43.9 0.1 0.0004 20.9 0.0 2.2 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding SOG2 PF10428.9 ORY42524.1 - 0.00047 19.5 22.5 0.00062 19.1 22.5 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein TFIIA PF03153.13 ORY42524.1 - 0.15 12.1 8.2 0.19 11.7 8.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 ORY42524.1 - 0.18 10.4 10.3 0.24 10.1 10.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hamartin PF04388.12 ORY42524.1 - 0.44 9.1 12.8 0.5 9.0 12.8 1.1 1 0 0 1 1 1 0 Hamartin protein Tmemb_cc2 PF10267.9 ORY42524.1 - 0.65 9.1 5.1 0.85 8.7 5.1 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SPX PF03105.19 ORY42524.1 - 1.4 8.7 16.0 2 8.3 16.0 1.2 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 ORY42524.1 - 1.6 7.2 8.2 2.1 6.8 8.2 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 ORY42524.1 - 2.2 7.0 11.9 3.5 6.4 11.9 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Peptidase_S64 PF08192.11 ORY42524.1 - 3.1 6.2 9.6 4 5.8 9.6 1.1 1 0 0 1 1 1 0 Peptidase family S64 Suf PF05843.14 ORY42524.1 - 3.9 7.4 7.2 5.3 6.9 7.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SRP-alpha_N PF04086.13 ORY42524.1 - 6.9 6.5 10.6 9.9 6.0 10.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 ORY42524.1 - 9.5 4.9 8.2 13 4.4 8.2 1.1 1 0 0 1 1 1 0 Presenilin PHD PF00628.29 ORY42525.1 - 1e-07 31.7 5.5 1.3e-07 31.4 5.5 1.2 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 ORY42525.1 - 0.0014 18.9 0.7 0.0021 18.3 0.7 1.3 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-C4_Topoisom PF01396.19 ORY42525.1 - 0.014 15.2 2.0 0.33 10.8 0.1 2.2 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger FANCL_C PF11793.8 ORY42525.1 - 0.081 13.1 1.4 0.081 13.1 1.4 1.8 2 0 0 2 2 2 0 FANCL C-terminal domain PhnA_Zn_Ribbon PF08274.12 ORY42525.1 - 0.34 10.9 0.3 0.34 10.9 0.3 2.5 2 1 0 2 2 2 0 PhnA Zinc-Ribbon Nab2 PF11517.8 ORY42526.1 - 0.7 10.2 5.1 0.53 10.6 0.0 3.4 4 0 0 4 4 4 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Sulfate_transp PF00916.20 ORY42527.1 - 1.1e-64 218.6 21.3 1.4e-64 218.3 21.3 1.1 1 0 0 1 1 1 1 Sulfate permease family MFS_MOT1 PF16983.5 ORY42527.1 - 0.0033 17.8 5.1 0.0033 17.8 5.1 3.6 3 2 1 4 4 4 1 Molybdate transporter of MFS superfamily PRD_Mga PF08270.11 ORY42527.1 - 0.046 13.4 0.1 0.073 12.7 0.1 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain E1_dh PF00676.20 ORY42529.1 - 3.9e-112 374.1 0.0 2.5e-111 371.4 0.0 1.8 2 0 0 2 2 2 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 ORY42529.1 - 0.056 12.6 0.1 0.09 12.0 0.1 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase DAO PF01266.24 ORY42530.1 - 9.2e-39 134.0 0.0 1.1e-38 133.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY42530.1 - 1.8e-07 31.3 0.0 3.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY42530.1 - 2.2e-05 23.9 0.0 0.00079 18.7 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY42530.1 - 0.00013 21.2 0.2 0.0011 18.2 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 ORY42530.1 - 0.00021 21.8 0.1 0.00067 20.2 0.0 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY42530.1 - 0.0012 18.1 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ORY42530.1 - 0.0027 16.5 0.0 0.0041 15.9 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 ORY42530.1 - 0.0038 16.4 0.1 0.24 10.5 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 ORY42530.1 - 0.022 14.1 0.0 0.98 8.7 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY42530.1 - 0.036 13.3 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 ORY42530.1 - 0.066 12.5 0.1 0.75 9.1 0.0 2.4 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 ORY42530.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.14 ORY42530.1 - 0.13 11.1 0.1 6.3 5.5 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Glu_dehyd_C PF16912.5 ORY42530.1 - 0.15 11.5 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus ECH_2 PF16113.5 ORY42531.1 - 1.5e-114 383.0 0.0 1.9e-114 382.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 ORY42531.1 - 5.8e-25 88.0 0.0 2.6e-24 85.9 0.0 1.9 2 1 1 3 3 3 1 Enoyl-CoA hydratase/isomerase FliG_N PF14842.6 ORY42531.1 - 0.064 13.8 0.0 0.23 12.0 0.0 1.9 2 0 0 2 2 2 0 FliG N-terminal domain HIGH_NTase1_ass PF16581.5 ORY42531.1 - 0.065 13.2 0.1 0.17 11.9 0.1 1.7 1 1 0 1 1 1 0 Cytidyltransferase-related C-terminal region TFIIA_gamma_C PF02751.14 ORY42532.1 - 0.89 9.8 5.8 1.6 9.0 5.8 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit FtsJ PF01728.19 ORY42534.1 - 6e-49 166.5 0.0 9.8e-49 165.8 0.0 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase DUF2196 PF09962.9 ORY42534.1 - 1.1e-07 31.7 0.4 6.5e-07 29.3 0.4 2.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) Methyltransf_31 PF13847.6 ORY42534.1 - 0.0033 17.3 0.0 0.22 11.3 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Ferric_reduct PF01794.19 ORY42535.1 - 1.1e-16 61.0 9.7 1.1e-16 61.0 9.7 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ORY42535.1 - 2.2e-10 40.6 0.0 5.5e-10 39.3 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 ORY42535.1 - 4.9e-08 33.2 0.1 1.6e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 ORY42535.1 - 0.0016 19.0 0.0 0.044 14.4 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain CSN8_PSD8_EIF3K PF10075.9 ORY42536.1 - 1e-18 67.7 0.8 1.7e-17 63.8 0.8 2.1 1 1 0 1 1 1 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 ORY42536.1 - 0.062 13.8 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 PCI domain Nairo_nucleo PF02477.15 ORY42536.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Nucleocapsid N protein Pkinase PF00069.25 ORY42537.1 - 5.4e-67 225.9 0.0 7.3e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY42537.1 - 1.2e-30 106.7 0.0 1.8e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TFIIA PF03153.13 ORY42537.1 - 2.3 8.1 12.0 3.1 7.7 12.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 ORY42537.1 - 6.4 4.9 11.0 8.3 4.5 11.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DHHC PF01529.20 ORY42539.1 - 5.1e-24 84.9 24.2 1.2e-12 48.1 8.6 3.0 3 0 0 3 3 3 2 DHHC palmitoyltransferase DUF5592 PF17332.2 ORY42539.1 - 0.62 10.7 5.2 0.16 12.5 2.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5592) RGCC PF15151.6 ORY42541.1 - 0.052 13.8 2.3 0.26 11.5 0.7 2.3 2 0 0 2 2 2 0 Response gene to complement 32 protein family Histone PF00125.24 ORY42542.1 - 8.6e-15 55.3 6.8 1.2e-13 51.6 3.8 2.8 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORY42542.1 - 0.0069 16.5 0.2 0.018 15.1 0.1 1.7 1 1 1 2 2 2 1 Centromere kinetochore component CENP-T histone fold PALP PF00291.25 ORY42543.1 - 3.3e-81 272.9 0.5 4.1e-81 272.6 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 ORY42543.1 - 2.7e-36 123.2 0.0 4.7e-17 61.5 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase N_BRCA1_IG PF16158.5 ORY42543.1 - 0.068 13.9 0.0 0.18 12.6 0.0 1.7 1 0 0 1 1 1 0 Ig-like domain from next to BRCA1 gene CPSase_C PF18302.1 ORY42543.1 - 0.11 12.9 0.1 0.31 11.5 0.1 1.8 1 0 0 1 1 1 0 Carbamoyl phosphate synthetase C-terminal domain Mito_carr PF00153.27 ORY42544.1 - 6.3e-64 212.0 0.9 1.2e-20 73.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HECT PF00632.25 ORY42545.1 - 8.5e-89 298.1 0.0 1e-88 297.8 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) tRNA-synt_1c PF00749.21 ORY42546.1 - 7.7e-106 353.5 0.0 1.1e-105 353.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 ORY42546.1 - 3.6e-45 154.0 0.0 7.8e-45 152.9 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.15 ORY42546.1 - 6.1e-38 130.4 3.1 6.1e-38 130.4 3.1 1.9 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.15 ORY42546.1 - 2.4e-07 31.6 1.9 5.7e-07 30.4 1.9 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 GATase_2 PF00310.21 ORY42546.1 - 0.029 13.1 0.3 0.044 12.5 0.3 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II UPF0253 PF06786.12 ORY42546.1 - 0.069 13.4 0.0 24 5.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0253) IL4_i_Ig PF18258.1 ORY42546.1 - 0.22 11.7 0.7 0.48 10.7 0.7 1.5 1 0 0 1 1 1 0 Interleukin-4 inducing immunoglobulin-binding domain Zn_clus PF00172.18 ORY42547.1 - 1.1e-13 51.0 24.6 3.5e-07 30.2 8.3 2.2 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.7 ORY42549.1 - 8.3e-08 32.7 0.0 1.9e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY42549.1 - 4.3e-06 27.2 0.0 1e-05 26.0 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) TIG PF01833.24 ORY42549.1 - 2.3e-05 24.4 3.0 3.6e-05 23.8 0.8 2.3 2 0 0 2 2 2 1 IPT/TIG domain Ank_5 PF13857.6 ORY42549.1 - 3.2e-05 24.1 0.0 0.021 15.1 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY42549.1 - 5.4e-05 23.3 0.0 0.094 13.3 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 ORY42549.1 - 0.0018 18.6 0.1 0.14 12.6 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Piwi PF02171.17 ORY42550.1 - 1.6e-86 290.3 0.0 2.6e-86 289.6 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 ORY42550.1 - 1.1e-11 44.7 0.0 2.2e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 ORY42550.1 - 2.9e-09 36.4 0.0 7.4e-09 35.1 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 ORY42550.1 - 1.6e-08 34.8 0.2 5.6e-08 33.0 0.1 2.0 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoMid PF16487.5 ORY42550.1 - 6.1e-05 23.2 0.0 0.00016 21.9 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute Hydrolase_4 PF12146.8 ORY42551.1 - 1e-15 57.7 0.0 1e-11 44.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY42551.1 - 2.4e-13 50.3 0.1 1.3e-12 47.9 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY42551.1 - 2.7e-11 44.5 0.1 4.2e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 ORY42551.1 - 4.7e-07 29.9 0.1 9.3e-07 28.9 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 ORY42551.1 - 0.00011 22.4 0.0 0.00018 21.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF818 PF05677.12 ORY42551.1 - 0.0003 19.9 0.0 0.00051 19.1 0.0 1.3 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S28 PF05577.12 ORY42551.1 - 0.00031 19.7 0.0 0.00046 19.1 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S15 PF02129.18 ORY42551.1 - 0.0041 16.8 0.0 0.062 12.9 0.0 2.1 1 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) LIDHydrolase PF10230.9 ORY42551.1 - 0.02 14.4 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 ORY42551.1 - 0.041 13.7 0.0 10 5.8 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase LIP PF03583.14 ORY42551.1 - 0.057 12.7 0.1 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Secretory lipase FSH1 PF03959.13 ORY42551.1 - 0.089 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF1057 PF06342.12 ORY42551.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) SH3_9 PF14604.6 ORY42553.1 - 2.3e-08 33.8 0.1 5.4e-08 32.6 0.1 1.7 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY42553.1 - 4.6e-07 29.4 0.0 1.4e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY42553.1 - 0.0053 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_16 PF18348.1 ORY42553.1 - 0.0076 16.0 0.1 0.016 15.0 0.1 1.5 1 0 0 1 1 1 1 Bacterial dipeptidyl-peptidase Sh3 domain APC_u9 PF16633.5 ORY42553.1 - 0.032 15.3 0.6 0.28 12.3 0.1 2.2 1 1 1 2 2 2 0 Unstructured region on APC between 1st two creatine-rich regions SH3_3 PF08239.11 ORY42553.1 - 0.17 12.2 0.4 1.3 9.4 0.0 2.4 3 0 0 3 3 3 0 Bacterial SH3 domain RNA_pol_L_2 PF13656.6 ORY42555.1 - 6e-33 112.5 0.0 6.7e-33 112.3 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 ORY42555.1 - 2.3e-16 59.0 0.0 2.9e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF5330 PF17264.2 ORY42555.1 - 0.056 13.5 0.0 0.087 12.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5330) CsgE PF10627.9 ORY42556.1 - 0.12 12.7 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Curli assembly protein CsgE CinA PF02464.17 ORY42557.1 - 9.7e-22 77.2 0.0 1.1e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 Competence-damaged protein Glyco_hydro_18 PF00704.28 ORY42558.1 - 2.4e-11 44.0 0.1 3.3e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ETRAMP PF09716.10 ORY42558.1 - 0.2 11.7 0.5 0.41 10.7 0.5 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) CwfJ_C_2 PF04676.14 ORY42559.1 - 1.9e-34 118.5 3.0 1.9e-34 118.5 3.0 2.0 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 ORY42559.1 - 1.1e-24 86.7 0.1 1.6e-24 86.1 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 ATP-synt_10 PF05176.14 ORY42560.1 - 3.4e-37 128.1 0.0 3.9e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein DUF1883 PF08980.10 ORY42560.1 - 0.11 12.5 0.0 0.3 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1883) CS PF04969.16 ORY42561.1 - 8e-06 26.8 0.0 1.2e-05 26.2 0.0 1.3 1 0 0 1 1 1 1 CS domain Bindin PF02084.15 ORY42561.1 - 0.035 14.4 7.5 0.052 13.8 7.5 1.3 1 0 0 1 1 1 0 Bindin Forkhead_N PF08430.12 ORY42561.1 - 0.27 11.8 15.7 0.42 11.2 15.7 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region Sporozoite_P67 PF05642.11 ORY42561.1 - 4.3 5.3 7.9 5.6 4.9 7.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TFA2_Winged_2 PF18121.1 ORY42562.1 - 2.1e-16 59.4 0.1 4.8e-16 58.2 0.1 1.7 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 ORY42562.1 - 5.2e-06 26.6 0.5 5.2e-06 26.6 0.5 1.6 2 0 0 2 2 2 1 TFIIE beta subunit core domain HTH_24 PF13412.6 ORY42562.1 - 0.066 12.8 0.2 6.1 6.5 0.1 2.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Virulence_fact PF13769.6 ORY42562.1 - 0.1 12.8 0.1 0.35 11.1 0.0 1.8 2 0 0 2 2 2 0 Virulence factor Fip1 PF05182.13 ORY42563.1 - 1.8e-25 88.2 0.5 4.2e-25 87.0 0.5 1.7 1 0 0 1 1 1 1 Fip1 motif Sporozoite_P67 PF05642.11 ORY42563.1 - 7.3 4.5 6.6 2.5 6.1 1.2 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Pkinase PF00069.25 ORY42566.1 - 5.1e-65 219.4 0.0 6e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY42566.1 - 2.7e-27 95.7 0.0 3.4e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY42566.1 - 0.011 14.7 0.0 0.086 11.8 0.0 2.1 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 ORY42566.1 - 0.049 13.5 0.0 0.34 10.8 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 ORY42566.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY42566.1 - 0.15 11.3 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 Kinase-like RRM_1 PF00076.22 ORY42567.1 - 4.5e-18 64.8 0.1 6.8e-18 64.3 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 ORY42567.1 - 4.9e-07 30.2 9.0 4.9e-07 30.2 9.0 3.2 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 DUF2181 PF10223.9 ORY42568.1 - 6.9e-46 156.7 0.0 9.4e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2181) p450 PF00067.22 ORY42569.1 - 8.6e-51 173.1 0.0 1.1e-50 172.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Lectin_leg-like PF03388.13 ORY42569.1 - 0.22 10.9 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 Legume-like lectin family MIP PF00230.20 ORY42570.1 - 1.7e-44 152.2 17.8 2.9e-27 95.9 6.8 2.1 2 0 0 2 2 2 2 Major intrinsic protein MM_CoA_mutase PF01642.22 ORY42571.1 - 3.8e-242 804.4 0.4 4.8e-242 804.0 0.4 1.1 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 ORY42571.1 - 6.2e-14 52.1 0.3 1.6e-13 50.7 0.3 1.7 1 0 0 1 1 1 1 B12 binding domain PhnI PF05861.12 ORY42571.1 - 0.037 12.9 0.0 0.13 11.1 0.0 1.8 2 0 0 2 2 2 0 Bacterial phosphonate metabolism protein (PhnI) PPR_2 PF13041.6 ORY42572.1 - 1.3e-35 121.3 2.8 2.3e-10 40.5 0.1 6.7 3 2 3 6 6 6 4 PPR repeat family PPR_3 PF13812.6 ORY42572.1 - 2.1e-28 98.2 0.0 1e-08 35.1 0.0 5.7 3 1 3 6 6 6 5 Pentatricopeptide repeat domain PPR PF01535.20 ORY42572.1 - 2.6e-25 86.8 6.4 5.6e-06 26.3 0.1 8.5 9 1 0 9 9 9 5 PPR repeat PPR_1 PF12854.7 ORY42572.1 - 6.6e-19 67.3 0.3 1.5e-05 24.6 0.0 5.8 5 0 0 5 5 5 4 PPR repeat PPR_long PF17177.4 ORY42572.1 - 1.5e-14 53.9 1.6 6e-14 51.9 0.1 2.6 2 1 1 3 3 3 1 Pentacotripeptide-repeat region of PRORP Terminase_4 PF05119.12 ORY42572.1 - 0.033 14.6 2.9 0.12 12.9 0.4 3.3 3 1 0 3 3 3 0 Phage terminase, small subunit RPN7 PF10602.9 ORY42572.1 - 0.085 12.6 0.7 0.85 9.3 0.4 2.8 2 1 0 2 2 2 0 26S proteasome subunit RPN7 Wzy_C_2 PF11846.8 ORY42572.1 - 0.29 11.0 0.8 1.3 8.9 0.1 2.4 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal IF-2B PF01008.17 ORY42573.1 - 2.3e-70 237.0 0.6 2.7e-70 236.8 0.6 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family G6PD_C PF02781.16 ORY42574.1 - 2e-116 388.2 0.0 2.9e-116 387.8 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 ORY42574.1 - 5.5e-54 183.5 0.0 8.9e-54 182.8 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain YIF1 PF03878.15 ORY42575.1 - 2.7e-78 262.8 9.7 2.9e-78 262.7 9.7 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 ORY42575.1 - 6.8e-08 32.4 7.4 8.4e-08 32.1 6.8 1.4 1 1 0 1 1 1 1 Yip1 domain DIOX_N PF14226.6 ORY42576.1 - 3.1e-23 82.8 0.0 4.8e-23 82.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY42576.1 - 5.2e-21 75.0 0.0 1.2e-20 73.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sec10 PF07393.11 ORY42578.1 - 2e-101 340.6 0.0 2.5e-101 340.3 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box PF00646.33 ORY42578.1 - 3.3e-06 26.8 0.0 7.5e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY42578.1 - 2e-05 24.4 0.0 4.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF1769 PF08588.10 ORY42580.1 - 3.8e-05 23.8 0.3 7.6e-05 22.8 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Peptidase_M28 PF04389.17 ORY42581.1 - 1.1e-29 103.5 0.0 1.6e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 ORY42581.1 - 0.025 13.6 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 ORY42581.1 - 0.061 13.0 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 CsgE PF10627.9 ORY42582.1 - 0.12 12.7 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Curli assembly protein CsgE Peptidase_M28 PF04389.17 ORY42583.1 - 4.2e-29 101.6 0.0 7.1e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 CPSase_sm_chain PF00988.22 ORY42584.1 - 5.5e-46 155.5 0.0 1.7e-45 154.0 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 ORY42584.1 - 2e-42 145.1 0.0 2.8e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORY42584.1 - 0.0002 21.2 0.4 0.038 13.7 0.2 2.9 1 1 1 2 2 2 2 Peptidase C26 DJ-1_PfpI PF01965.24 ORY42584.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Glyco_transf_8 PF01501.20 ORY42586.1 - 2.7e-07 30.4 0.0 2.5e-06 27.2 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 ORY42586.1 - 0.051 13.5 0.1 0.072 13.0 0.1 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.8 ORY42586.1 - 0.053 12.9 0.2 0.082 12.2 0.2 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative SQHop_cyclase_C PF13243.6 ORY42587.1 - 5.5e-55 186.7 2.5 3.6e-51 174.2 0.4 2.7 2 1 1 3 3 3 3 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 ORY42587.1 - 2.2e-48 164.8 0.0 1.5e-40 139.1 0.0 4.2 3 1 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 ORY42587.1 - 1.1e-34 117.8 7.1 3.9e-11 42.5 0.0 6.2 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 ORY42587.1 - 1.9e-05 23.8 0.5 0.0012 17.9 0.2 3.4 3 1 1 4 4 4 1 A-macroglobulin TED domain Pec_lyase PF09492.10 ORY42587.1 - 0.00035 20.0 0.7 1.2 8.3 0.0 3.6 2 1 2 4 4 4 2 Pectic acid lyase DUF4568 PF15132.6 ORY42587.1 - 2.8 7.3 4.4 7 6.0 0.8 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4568) Ribosomal_S6 PF01250.17 ORY42588.1 - 1.3e-17 63.9 0.0 3.9e-16 59.1 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S6 Vps53_N PF04100.12 ORY42589.1 - 4.9e-101 338.5 8.4 4.9e-101 338.5 8.4 1.6 2 0 0 2 2 2 1 Vps53-like, N-terminal CEP63 PF17045.5 ORY42589.1 - 0.006 16.5 5.6 0.011 15.7 5.6 1.3 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa Spc7 PF08317.11 ORY42589.1 - 0.007 15.3 6.4 0.012 14.5 6.4 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein VPS53_C PF16854.5 ORY42589.1 - 0.013 15.4 0.3 0.11 12.4 0.0 2.5 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 53 C-terminus NBD94 PF16830.5 ORY42589.1 - 0.46 10.9 3.8 1 9.8 0.7 3.0 3 0 0 3 3 3 0 Nucleotide-Binding Domain 94 of RH Dict-STAT-coil PF09267.10 ORY42589.1 - 0.71 10.3 6.1 2.1 8.8 3.6 2.7 1 1 1 2 2 2 0 Dictyostelium STAT, coiled coil Chorion_3 PF05387.11 ORY42589.1 - 4.9 6.7 9.5 8.3 6.0 9.5 1.3 1 0 0 1 1 1 0 Chorion family 3 AhpC-TSA PF00578.21 ORY42590.1 - 7.6e-40 135.7 0.0 1.3e-39 135.0 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY42590.1 - 2.3e-14 53.4 0.0 3.1e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 ORY42590.1 - 6.5e-10 38.7 0.0 1.2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 ORY42590.1 - 0.028 14.3 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 SCO1/SenC Erythro-docking PF09277.11 ORY42590.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Erythronolide synthase, docking AhpC-TSA PF00578.21 ORY42591.1 - 3.1e-36 124.0 0.0 4.7e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY42591.1 - 1.8e-15 56.9 0.0 2.4e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 ORY42591.1 - 1.4e-12 47.2 0.2 6.1e-12 45.2 0.0 1.9 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA PF00578.21 ORY42592.1 - 4.2e-40 136.5 0.0 6.3e-40 135.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY42592.1 - 8.8e-16 57.9 0.0 1.1e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 ORY42592.1 - 8.3e-10 38.3 0.0 1.4e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 ORY42592.1 - 0.0031 17.4 0.0 0.021 14.7 0.0 2.1 2 0 0 2 2 2 1 SCO1/SenC Erythro-docking PF09277.11 ORY42592.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Erythronolide synthase, docking SIR2 PF02146.17 ORY42593.1 - 3.9e-55 186.5 0.0 6.4e-35 120.7 0.0 2.4 2 0 0 2 2 2 2 Sir2 family Gly_transf_sug PF04488.15 ORY42594.1 - 4.3e-15 56.1 0.0 9.6e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 ORY42594.1 - 9.2e-06 25.2 0.1 1.3e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Methyltransf_24 PF13578.6 ORY42595.1 - 0.12 13.4 0.0 0.43 11.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain TFIIA PF03153.13 ORY42595.1 - 3.5 7.5 24.1 1.3e+02 2.4 24.5 2.2 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Chorein_N PF12624.7 ORY42596.1 - 0.019 15.1 1.0 0.019 15.1 1.0 1.8 2 0 0 2 2 2 0 N-terminal region of Chorein or VPS13 DUF4205 PF13898.6 ORY42597.1 - 3.2e-94 315.7 0.0 4.9e-94 315.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) Ank_2 PF12796.7 ORY42598.1 - 5.1e-07 30.2 8.2 0.00079 20.0 0.3 3.2 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY42598.1 - 0.00055 20.4 1.9 0.87 10.2 0.1 3.9 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY42598.1 - 0.049 14.2 1.9 1.6e+02 3.4 0.0 5.1 5 0 0 5 5 5 0 Ankyrin repeat Ank PF00023.30 ORY42598.1 - 0.33 11.5 8.5 0.64 10.6 0.0 4.3 5 0 0 5 5 5 0 Ankyrin repeat Aminotran_3 PF00202.21 ORY42599.1 - 8.1e-103 344.2 0.1 9.2e-103 344.0 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 ORY42599.1 - 0.018 14.3 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II OAM_dimer PF16554.5 ORY42599.1 - 0.062 13.7 0.1 0.33 11.4 0.0 2.1 3 0 0 3 3 3 0 Dimerisation domain of d-ornithine 4,5-aminomutase Epimerase PF01370.21 ORY42600.1 - 4.5e-19 68.9 0.0 5.5e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY42600.1 - 6.7e-13 48.7 0.1 5.4e-12 45.7 0.1 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ORY42600.1 - 1.7e-10 40.5 0.0 2.4e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 ORY42600.1 - 1.5e-06 27.4 0.0 3e-06 26.5 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORY42600.1 - 0.00034 19.9 0.0 0.0015 17.8 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 ORY42600.1 - 0.00058 19.1 0.3 0.015 14.4 0.3 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Aminotran_1_2 PF00155.21 ORY42601.1 - 4.5e-74 249.8 0.0 5.4e-74 249.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 ORY42601.1 - 0.0023 16.9 0.0 0.018 14.0 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 ORY42601.1 - 0.045 13.0 0.0 0.15 11.4 0.0 1.6 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 ORY42601.1 - 0.06 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 ORY42601.1 - 0.066 11.7 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Galactosyl_T PF01762.21 ORY42602.1 - 1.6e-13 50.9 0.0 5.5e-08 32.8 0.0 4.0 3 1 1 4 4 4 3 Galactosyltransferase Fringe PF02434.16 ORY42602.1 - 0.0033 16.9 0.1 0.036 13.5 0.0 2.3 2 0 0 2 2 2 1 Fringe-like Galactosyl_T PF01762.21 ORY42603.1 - 4.5e-12 46.2 0.3 2.4e-08 34.0 0.1 2.9 2 1 1 3 3 3 2 Galactosyltransferase Fringe PF02434.16 ORY42603.1 - 0.0036 16.8 0.6 0.0071 15.8 0.1 1.7 2 0 0 2 2 2 1 Fringe-like PMSR PF01625.21 ORY42604.1 - 0.00041 20.6 3.0 0.0011 19.1 1.5 2.3 2 1 0 2 2 2 1 Peptide methionine sulfoxide reductase Galactosyl_T PF01762.21 ORY42605.1 - 3.1e-09 37.0 0.6 2.8e-08 33.8 0.1 2.2 2 0 0 2 2 2 1 Galactosyltransferase Galactosyl_T PF01762.21 ORY42606.1 - 5.3e-12 46.0 0.3 2.1e-08 34.2 0.1 3.2 2 1 1 3 3 3 2 Galactosyltransferase Fringe PF02434.16 ORY42606.1 - 0.00062 19.3 0.5 0.01 15.3 0.1 2.5 3 0 0 3 3 3 1 Fringe-like DnaG_DnaB_bind PF08278.11 ORY42607.1 - 0.002 18.7 0.4 0.002 18.7 0.4 2.1 2 0 0 2 2 2 1 DNA primase DnaG DnaB-binding Ldh_1_N PF00056.23 ORY42607.1 - 0.057 13.5 0.3 0.083 13.0 0.3 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain CaM_bdg_C0 PF10562.9 ORY42607.1 - 3.6 7.7 4.9 6.6 6.9 0.5 2.9 3 0 0 3 3 3 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit SAPS PF04499.15 ORY42608.1 - 1.5e-96 324.2 3.6 1.3e-58 199.1 1.1 2.5 3 0 0 3 3 3 2 SIT4 phosphatase-associated protein YqzH PF14164.6 ORY42608.1 - 0.014 15.4 0.0 3.8 7.6 0.0 3.0 2 0 0 2 2 2 0 YqzH-like protein Sel1 PF08238.12 ORY42609.1 - 1.8e-59 196.8 43.1 3.7e-07 30.6 0.2 14.4 13 1 0 13 13 13 11 Sel1 repeat TPR_6 PF13174.6 ORY42609.1 - 0.0047 17.5 13.2 5.7 7.8 0.0 8.4 10 1 0 10 10 10 2 Tetratricopeptide repeat ABC_tran PF00005.27 ORY42611.1 - 2.6e-27 96.0 0.0 4.3e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 ORY42611.1 - 0.00028 20.8 0.1 0.00063 19.7 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 ORY42611.1 - 0.00058 19.4 0.1 0.021 14.3 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 ORY42611.1 - 0.00078 18.6 0.1 0.0012 17.9 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 ORY42611.1 - 0.0052 16.5 0.2 0.012 15.3 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 ORY42611.1 - 0.0077 16.8 0.1 0.013 16.0 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.7 ORY42611.1 - 0.0095 14.9 0.1 0.014 14.3 0.1 1.2 1 0 0 1 1 1 1 AAA-like domain AAA_30 PF13604.6 ORY42611.1 - 0.014 15.1 0.1 0.027 14.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ORY42611.1 - 0.015 15.4 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 ORY42611.1 - 0.016 15.0 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ORY42611.1 - 0.016 15.5 0.0 0.035 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY42611.1 - 0.042 14.2 0.0 0.084 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_21 PF13304.6 ORY42611.1 - 0.049 13.4 2.6 0.5 10.1 0.2 2.7 2 2 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 ORY42611.1 - 0.096 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 ORY42611.1 - 0.24 11.3 0.0 0.53 10.2 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain ABC_tran PF00005.27 ORY42612.1 - 1.9e-28 99.7 0.1 5e-28 98.3 0.1 1.8 2 0 0 2 2 2 1 ABC transporter ABC2_membrane PF01061.24 ORY42612.1 - 1.1e-10 41.3 9.3 2.4e-10 40.2 9.3 1.5 1 0 0 1 1 1 1 ABC-2 type transporter RsgA_GTPase PF03193.16 ORY42612.1 - 0.00093 19.1 0.1 0.0018 18.2 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 ORY42612.1 - 0.014 15.2 0.1 0.04 13.6 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 ORY42612.1 - 0.021 14.5 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 ORY42612.1 - 0.022 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 ORY42612.1 - 0.034 14.2 0.2 0.25 11.4 0.1 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY42612.1 - 0.037 14.4 0.0 0.08 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 ORY42612.1 - 0.04 14.4 0.0 0.066 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 ORY42612.1 - 0.06 12.8 0.1 1.1 8.6 0.1 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 ORY42612.1 - 0.092 12.3 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ORY42612.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain RecA PF00154.21 ORY42612.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 recA bacterial DNA recombination protein ATPase PF06745.13 ORY42612.1 - 0.19 11.1 0.2 0.36 10.1 0.2 1.4 1 0 0 1 1 1 0 KaiC AAA_21 PF13304.6 ORY42612.1 - 0.19 11.5 0.8 5.7 6.7 0.1 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system VID27 PF08553.10 ORY42614.1 - 5e-127 423.8 0.0 8.6e-127 423.0 0.0 1.3 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 ORY42614.1 - 2.7e-37 128.3 0.3 2.7e-37 128.3 0.3 4.1 3 1 1 4 4 4 1 VID27 N-terminal region VID27_PH PF17747.1 ORY42614.1 - 2.5e-20 72.8 0.2 6.5e-20 71.5 0.2 1.8 1 0 0 1 1 1 1 VID27 PH-like domain Rap1_C PF11626.8 ORY42615.1 - 0.0066 16.5 0.3 0.0066 16.5 0.3 2.5 3 0 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF4778 PF16008.5 ORY42615.1 - 1.2 9.1 12.0 0.059 13.4 4.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) Peptidase_S10 PF00450.22 ORY42617.1 - 1.4e-103 347.5 0.0 1.8e-103 347.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase HTH_Tnp_1 PF01527.20 ORY42618.1 - 0.00094 19.5 0.2 0.029 14.7 0.2 2.2 1 1 0 1 1 1 1 Transposase HTH_28 PF13518.6 ORY42618.1 - 0.0092 16.1 0.0 0.019 15.1 0.0 1.7 1 1 0 1 1 1 1 Helix-turn-helix domain Histone PF00125.24 ORY42619.1 - 1.4e-15 57.8 6.7 1.9e-14 54.2 3.7 2.8 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORY42619.1 - 0.0046 17.1 0.2 0.016 15.3 0.1 1.9 1 1 1 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 ORY42619.1 - 0.2 12.0 0.7 2.6 8.4 0.1 2.2 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CsgE PF10627.9 ORY42623.1 - 0.12 12.7 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Curli assembly protein CsgE AIG1 PF04548.16 ORY42624.1 - 5.9e-08 32.3 0.0 0.00028 20.3 0.0 2.6 2 0 0 2 2 2 2 AIG1 family MMR_HSR1 PF01926.23 ORY42624.1 - 1.2e-06 28.6 0.2 0.052 13.6 0.0 3.5 3 0 0 3 3 3 2 50S ribosome-binding GTPase Septin PF00735.18 ORY42624.1 - 0.00025 20.4 0.0 0.00078 18.8 0.0 1.8 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 ORY42624.1 - 0.00049 20.0 0.3 0.0034 17.3 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 ORY42624.1 - 0.00088 19.8 0.1 0.00088 19.8 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY42624.1 - 0.0016 18.8 0.0 0.0047 17.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 ORY42624.1 - 0.0036 17.0 1.6 0.01 15.6 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 ORY42624.1 - 0.0042 16.8 0.0 0.0097 15.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Radical_SAM PF04055.21 ORY42624.1 - 0.0059 17.0 0.2 0.027 14.8 0.1 2.1 2 0 0 2 2 2 1 Radical SAM superfamily ABC_tran PF00005.27 ORY42624.1 - 0.0074 16.8 0.3 0.088 13.3 0.0 2.7 2 0 0 2 2 2 1 ABC transporter Dynamin_N PF00350.23 ORY42624.1 - 0.016 15.3 1.8 0.057 13.5 0.3 2.7 2 1 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 ORY42624.1 - 0.021 14.2 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family TniB PF05621.11 ORY42624.1 - 0.022 14.2 0.0 0.1 12.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein RNA_helicase PF00910.22 ORY42624.1 - 0.1 13.0 0.4 1.3 9.4 0.0 3.1 3 0 0 3 3 3 0 RNA helicase Pkinase PF00069.25 ORY42626.1 - 0.04 13.3 0.2 0.096 12.0 0.1 1.6 2 0 0 2 2 2 0 Protein kinase domain Kdo PF06293.14 ORY42626.1 - 0.054 12.8 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TRM13 PF05206.14 ORY42629.1 - 3e-64 217.1 0.2 4.5e-64 216.5 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 ORY42629.1 - 4.7e-06 26.3 0.7 4.7e-06 26.3 0.7 2.3 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein PSI_integrin PF17205.3 ORY42629.1 - 0.0022 17.7 0.8 0.0076 16.0 0.8 2.0 1 0 0 1 1 1 1 Integrin plexin domain GATase_5 PF13507.6 ORY42630.1 - 3.1e-87 292.0 0.0 4.8e-87 291.3 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 ORY42630.1 - 1.7e-42 145.2 0.8 1.1e-26 93.8 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 ORY42630.1 - 1.6e-29 102.2 0.0 3e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 ORY42630.1 - 4e-22 78.5 0.0 7.8e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain ArfGap PF01412.18 ORY42631.1 - 4.1e-07 30.1 0.0 7.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf HEAT_2 PF13646.6 ORY42632.1 - 0.013 15.9 0.0 0.032 14.6 0.0 1.6 1 0 0 1 1 1 0 HEAT repeats zf-HC5HC2H PF13771.6 ORY42633.1 - 0.18 12.1 9.4 0.07 13.4 1.8 2.8 2 1 1 3 3 3 0 PHD-like zinc-binding domain C1_1 PF00130.22 ORY42633.1 - 3.9 7.4 18.3 1 9.3 9.5 2.7 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MCM_OB PF17207.3 ORY42634.1 - 0.04 13.8 0.1 0.057 13.3 0.1 1.3 1 0 0 1 1 1 0 MCM OB domain Zf_RING PF16744.5 ORY42635.1 - 0.088 12.9 4.1 0.23 11.6 4.1 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger Pkinase_Tyr PF07714.17 ORY42636.1 - 0.034 13.4 0.1 0.052 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase PIF1 PF05970.14 ORY42646.1 - 6.7e-14 51.8 0.0 1.2e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase Helitron_like_N PF14214.6 ORY42646.1 - 2.9e-08 34.1 0.0 6.9e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 ORY42646.1 - 0.00015 21.5 0.0 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF4452 PF14618.6 ORY42646.1 - 0.055 13.3 0.5 0.14 12.0 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) AAA_5 PF07728.14 ORY42646.1 - 0.06 13.3 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Pkinase PF00069.25 ORY42648.1 - 0.029 13.8 0.1 0.04 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein kinase domain PB1 PF00564.24 ORY42652.1 - 0.019 14.9 0.0 9.7 6.2 0.0 2.7 2 0 0 2 2 2 0 PB1 domain F-box-like PF12937.7 ORY42654.1 - 0.00014 21.7 0.3 0.0004 20.2 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY42654.1 - 0.00025 20.8 0.4 0.00059 19.6 0.4 1.7 1 0 0 1 1 1 1 F-box domain PRORP PF16953.5 ORY42655.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein-only RNase P SPATA1_C PF15743.5 ORY42658.1 - 0.0033 17.5 3.5 0.005 16.9 3.5 1.2 1 0 0 1 1 1 1 Spermatogenesis-associated C-terminus DUF4355 PF14265.6 ORY42658.1 - 0.11 12.7 7.7 0.2 11.9 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) FlaC_arch PF05377.11 ORY42658.1 - 0.38 11.2 2.3 2.9 8.4 0.1 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 ORY42658.1 - 2.3 7.4 5.4 3.6 6.8 5.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF2203 PF09969.9 ORY42658.1 - 9.2 7.0 7.4 5.8 7.7 5.2 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF3450 PF11932.8 ORY42659.1 - 0.00077 18.8 1.2 0.001 18.4 1.0 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) Nsp1_C PF05064.13 ORY42659.1 - 0.00095 19.0 1.0 0.0011 18.8 1.0 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region ZapB PF06005.12 ORY42659.1 - 0.0011 19.4 4.4 0.0014 19.0 4.4 1.3 1 1 0 1 1 1 1 Cell division protein ZapB BLOC1_2 PF10046.9 ORY42659.1 - 0.0022 18.2 0.8 0.0029 17.9 0.8 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 ORY42659.1 - 0.0029 17.5 0.9 0.0033 17.3 0.9 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 BST2 PF16716.5 ORY42659.1 - 0.0042 17.6 2.2 0.0053 17.3 2.2 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 GAS PF13851.6 ORY42659.1 - 0.0057 16.0 2.8 0.0064 15.9 2.8 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding YabA PF06156.13 ORY42659.1 - 0.018 15.6 1.2 0.022 15.4 1.2 1.2 1 0 0 1 1 1 0 Initiation control protein YabA CCDC92 PF14916.6 ORY42659.1 - 0.019 14.7 3.5 0.034 13.9 3.3 1.6 1 1 0 1 1 1 0 Coiled-coil domain of unknown function Cluap1 PF10234.9 ORY42659.1 - 0.019 14.4 1.4 0.02 14.3 1.4 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Herpes_UL6 PF01763.16 ORY42659.1 - 0.019 13.5 1.5 0.02 13.5 1.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like HlyD_D23 PF16576.5 ORY42659.1 - 0.027 13.7 1.0 0.029 13.6 1.0 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion TMF_DNA_bd PF12329.8 ORY42659.1 - 0.034 14.1 1.1 0.034 14.1 1.1 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Rab_bind PF16704.5 ORY42659.1 - 0.034 14.2 0.3 2.8 8.1 0.1 2.3 1 1 1 2 2 2 0 Rab binding domain Sec34 PF04136.15 ORY42659.1 - 0.035 14.0 1.3 0.039 13.8 1.3 1.1 1 0 0 1 1 1 0 Sec34-like family APG6_N PF17675.1 ORY42659.1 - 0.046 14.3 2.7 0.062 13.8 2.7 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF948 PF06103.11 ORY42659.1 - 0.077 13.3 0.4 0.11 12.8 0.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 ORY42659.1 - 0.13 12.5 2.9 0.52 10.5 2.8 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 ORY42659.1 - 0.14 12.4 1.7 0.27 11.5 1.7 1.5 1 0 0 1 1 1 0 Haemolysin XhlA USP8_interact PF08941.10 ORY42659.1 - 0.15 11.9 1.9 0.18 11.6 1.9 1.1 1 0 0 1 1 1 0 USP8 interacting SlyX PF04102.12 ORY42659.1 - 0.27 11.9 4.6 2.1 9.0 4.6 2.1 1 1 0 1 1 1 0 SlyX DivIC PF04977.15 ORY42659.1 - 0.77 9.6 4.7 3.7 7.4 4.7 2.0 1 1 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 ORY42659.1 - 0.98 9.6 3.9 3.9 7.6 1.2 2.3 1 1 1 2 2 2 0 Basic region leucine zipper AAA PF00004.29 ORY42724.1 - 3e-23 82.7 0.0 1.7e-22 80.3 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ORY42724.1 - 0.015 15.0 0.0 0.083 12.6 0.0 2.2 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 ORY42724.1 - 0.032 14.4 0.3 0.34 11.1 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 ORY42724.1 - 0.086 13.2 0.0 0.27 11.6 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain VWA_2 PF13519.6 ORY42725.1 - 1.6e-08 35.1 0.0 8.4e-08 32.8 0.0 2.3 1 0 0 1 1 1 1 von Willebrand factor type A domain RHD3 PF05879.12 ORY42725.1 - 5.6e-07 28.1 1.3 1.1e-06 27.2 0.1 2.1 2 1 0 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) VWA PF00092.28 ORY42725.1 - 1.2e-05 25.6 0.1 0.0003 21.1 0.0 3.0 2 1 0 2 2 2 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 ORY42725.1 - 6.1e-05 23.2 0.0 0.00035 20.7 0.0 2.3 1 1 0 1 1 1 1 vWA found in TerF C terminus GBP PF02263.19 ORY42725.1 - 6.9e-05 22.2 0.1 0.00025 20.4 0.0 1.8 1 1 1 2 2 2 1 Guanylate-binding protein, N-terminal domain DUF2849 PF11011.8 ORY42725.1 - 0.27 11.9 1.1 0.52 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2849) Cu-oxidase PF00394.22 ORY42727.1 - 2.6e-39 134.9 0.2 5.4e-38 130.6 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY42727.1 - 1.3e-35 122.1 8.6 5.4e-15 55.3 0.1 4.3 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORY42727.1 - 1.6e-33 115.2 8.0 2.5e-32 111.4 0.5 4.0 5 0 0 5 5 5 2 Multicopper oxidase Lum_binding PF00677.17 ORY42727.1 - 0.16 12.0 0.1 0.35 10.9 0.1 1.6 1 0 0 1 1 1 0 Lumazine binding domain UCH PF00443.29 ORY42728.1 - 4.3e-46 157.5 0.0 9.8e-46 156.3 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 ORY42728.1 - 2.6e-18 65.5 0.9 2.6e-18 65.5 0.9 3.2 3 0 0 3 3 3 1 Variant UBP zinc finger zf-UBP PF02148.19 ORY42728.1 - 5e-18 65.2 0.5 5e-18 65.2 0.5 4.0 4 0 0 4 4 4 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 ORY42728.1 - 6.4e-18 65.4 0.0 2.6e-15 56.8 0.0 3.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.31 ORY42728.1 - 2.4e-16 59.3 1.4 1.1e-07 31.6 0.1 3.0 3 0 0 3 3 3 2 UBA/TS-N domain WD40 PF00400.32 ORY42729.1 - 4.5e-18 65.3 5.3 3.3e-08 34.1 0.0 4.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY42729.1 - 9.3e-08 32.3 0.0 0.00046 20.4 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY42729.1 - 0.0024 16.6 0.9 0.25 9.9 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 LETM1 PF07766.13 ORY42730.1 - 8e-94 313.9 2.3 8e-94 313.9 2.3 1.8 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.6 ORY42730.1 - 4e-05 24.0 0.0 0.0003 21.2 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 ORY42730.1 - 6.5e-05 22.7 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 ORY42730.1 - 0.00024 20.4 0.0 0.0017 17.7 0.0 2.4 2 0 0 2 2 2 1 EF hand SAP PF02037.27 ORY42730.1 - 0.0022 17.7 0.2 0.046 13.5 0.0 3.0 3 0 0 3 3 3 1 SAP domain EF-hand_6 PF13405.6 ORY42730.1 - 0.0064 16.3 0.0 0.42 10.7 0.0 3.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 ORY42730.1 - 0.011 15.1 0.2 0.062 12.8 0.0 2.4 3 0 0 3 3 3 0 EF hand RPA_interact_N PF14766.6 ORY42731.1 - 5.5e-07 29.1 0.3 7.8e-07 28.6 0.3 1.3 1 0 0 1 1 1 1 Replication protein A interacting N-terminal RPA_interact_C PF14768.6 ORY42731.1 - 0.00026 21.5 0.2 0.00064 20.2 0.2 1.7 1 0 0 1 1 1 1 Replication protein A interacting C-terminal Zn_Tnp_IS1 PF03811.13 ORY42731.1 - 0.29 10.9 5.3 0.6 9.9 0.0 2.6 2 0 0 2 2 2 0 InsA N-terminal domain Polyketide_cyc2 PF10604.9 ORY42733.1 - 0.0013 19.0 0.1 0.036 14.3 0.0 2.5 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 ORY42733.1 - 0.0034 17.6 0.1 0.094 12.9 0.0 2.4 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Ribosomal_S8e PF01201.22 ORY42734.1 - 4e-50 169.5 8.5 1.4e-49 167.8 8.5 1.8 1 1 0 1 1 1 1 Ribosomal protein S8e DEAD PF00270.29 ORY42735.1 - 1.3e-05 25.1 0.1 1.6e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ORY42735.1 - 0.00097 19.2 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORY42736.1 - 8.1e-07 29.4 0.1 1.9e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1604 PF07713.13 ORY42737.1 - 3.5e-36 122.9 1.0 3.5e-36 122.9 1.0 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.23 ORY42737.1 - 5.8e-07 29.3 0.0 1.5e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 ORY42737.1 - 0.013 15.6 0.0 0.013 15.6 0.0 2.9 2 0 0 2 2 2 0 G-patch domain Sec3_C PF09763.9 ORY42737.1 - 0.37 9.1 7.9 0.59 8.4 7.9 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 Neur_chan_memb PF02932.16 ORY42737.1 - 2.7 8.0 4.8 7 6.6 4.8 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BolA PF01722.18 ORY42738.1 - 1.1e-12 48.1 0.2 5.3e-12 45.8 0.0 2.1 1 1 1 2 2 2 1 BolA-like protein Stb3 PF10330.9 ORY42738.1 - 0.0043 17.1 0.0 0.0061 16.6 0.0 1.2 1 0 0 1 1 1 1 Putative Sin3 binding protein Guanylate_cyc PF00211.20 ORY42739.1 - 2.4e-09 37.0 0.1 0.00014 21.6 0.2 2.5 2 1 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 ORY42739.1 - 1.9e-05 25.1 0.0 3.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.17 ORY42739.1 - 0.0035 17.1 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 ORY42739.1 - 0.11 12.8 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ORY42739.1 - 0.18 11.7 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase FoP_duplication PF13865.6 ORY42740.1 - 0.036 14.6 11.6 0.055 14.0 11.6 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Cdc13_OB2 PF18691.1 ORY42741.1 - 0.046 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Cell division control protein 13, OB2 domain Voldacs PF03517.13 ORY42741.1 - 0.22 11.6 2.3 1.1 9.4 0.1 2.6 3 0 0 3 3 3 0 Regulator of volume decrease after cellular swelling S-methyl_trans PF02574.16 ORY42742.1 - 0.017 14.9 0.1 0.76 9.5 0.0 2.2 1 1 0 2 2 2 0 Homocysteine S-methyltransferase ubiquitin PF00240.23 ORY42743.1 - 0.00041 20.0 0.0 0.0066 16.2 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin family TPT PF03151.16 ORY42744.1 - 3.3e-08 33.2 21.3 6.3e-05 22.5 2.0 3.0 3 0 0 3 3 3 2 Triose-phosphate Transporter family EamA PF00892.20 ORY42744.1 - 0.0021 18.3 15.2 0.0021 18.3 15.2 3.4 3 1 0 3 3 3 2 EamA-like transporter family SH3_9 PF14604.6 ORY42745.1 - 3e-14 52.6 0.0 3.1e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 ORY42745.1 - 4e-12 45.5 0.0 1.8e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 ORY42745.1 - 6.3e-07 29.0 0.0 0.00015 21.4 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain Stevor PF17410.2 ORY42745.1 - 0.06 12.9 0.5 0.06 12.9 0.5 1.6 2 0 0 2 2 2 0 Subtelomeric Variable Open Reading frame MaAIMP_sms PF16951.5 ORY42745.1 - 0.13 12.0 0.6 0.34 10.7 0.2 1.9 2 0 0 2 2 2 0 Putative methionine and alanine importer, small subunit LapA_dom PF06305.11 ORY42745.1 - 0.87 9.4 2.4 1.5 8.7 2.4 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Thioredoxin PF00085.20 ORY42746.1 - 3.5e-58 194.0 6.5 4.7e-30 103.6 0.2 4.3 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 ORY42746.1 - 3e-37 128.3 7.2 3.6e-32 111.7 4.2 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.17 ORY42746.1 - 7.8e-11 41.6 1.8 7.8e-11 41.6 1.8 1.5 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_8 PF13905.6 ORY42746.1 - 2e-07 31.2 2.2 0.095 13.0 0.0 4.5 4 2 1 5 5 5 2 Thioredoxin-like AhpC-TSA PF00578.21 ORY42746.1 - 6e-07 29.4 1.6 0.0048 16.8 0.0 3.4 3 0 0 3 3 3 1 AhpC/TSA family Thioredoxin_7 PF13899.6 ORY42746.1 - 5.2e-06 26.6 0.3 0.055 13.6 0.0 3.2 4 0 0 4 4 4 2 Thioredoxin-like Redoxin PF08534.10 ORY42746.1 - 0.00034 20.3 1.5 0.8 9.4 0.0 3.0 3 0 0 3 3 3 2 Redoxin Thioredoxin_2 PF13098.6 ORY42746.1 - 0.00062 20.2 2.5 1.4 9.4 0.1 3.5 3 2 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 ORY42746.1 - 0.0051 16.2 0.2 2.2 7.5 0.0 3.1 3 1 0 3 3 3 2 OST3 / OST6 family, transporter family TraF PF13728.6 ORY42746.1 - 0.034 14.0 0.0 1.9 8.3 0.0 2.4 2 0 0 2 2 2 0 F plasmid transfer operon protein ERp29_N PF07912.13 ORY42746.1 - 0.049 13.8 1.0 0.3 11.2 0.0 2.8 4 0 0 4 4 4 0 ERp29, N-terminal domain Thioredoxin_9 PF14595.6 ORY42746.1 - 0.17 11.7 0.2 5.6 6.7 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin Guanylate_cyc PF00211.20 ORY42747.1 - 3.2e-10 39.9 0.1 9.8e-06 25.3 0.1 2.6 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 ORY42747.1 - 3.5e-06 27.5 0.0 4.1e-05 24.0 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain Ank_2 PF12796.7 ORY42748.1 - 2.7e-32 111.2 2.9 7.5e-12 45.7 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY42748.1 - 6.2e-20 69.2 4.4 0.00055 20.2 0.0 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 ORY42748.1 - 1.7e-17 63.2 2.5 1.5e-05 25.2 0.0 5.8 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY42748.1 - 4.8e-17 61.6 3.8 1.9e-05 24.9 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.6 ORY42748.1 - 7.1e-16 58.4 0.8 2.3e-05 24.9 0.1 4.4 2 1 3 5 5 5 5 Ankyrin repeats (many copies) DUF4998 PF16389.5 ORY42748.1 - 0.00092 18.8 0.1 0.022 14.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function fn3 PF00041.21 ORY42748.1 - 0.0044 17.3 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain CCDC-167 PF15188.6 ORY42748.1 - 0.053 13.9 0.3 0.1 12.9 0.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF2369 PF10179.9 ORY42748.1 - 0.095 13.1 0.1 0.23 11.9 0.1 1.7 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) NP1-WLL PF11733.8 ORY42749.1 - 0.1 12.3 2.7 0.17 11.7 2.7 1.4 1 0 0 1 1 1 0 Non-capsid protein NP1 Dishevelled PF02377.15 ORY42749.1 - 8.2 6.8 15.5 1.6 9.1 6.1 2.2 1 1 1 2 2 2 0 Dishevelled specific domain CRIM PF16978.5 ORY42750.1 - 1.9e-34 118.8 0.0 4.2e-34 117.7 0.0 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 ORY42750.1 - 4.5e-12 46.2 0.0 9.9e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TFIIA PF03153.13 ORY42750.1 - 0.032 14.2 10.9 0.077 13.0 10.9 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 ORY42750.1 - 1.7 8.2 13.8 2.8 7.5 13.8 1.3 1 0 0 1 1 1 0 Spt20 family AMP-binding PF00501.28 ORY42751.1 - 4.7e-80 269.2 0.0 5.8e-80 268.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY42751.1 - 2.2e-13 51.0 0.4 7.6e-13 49.3 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain WD40 PF00400.32 ORY42752.1 - 6.3e-10 39.5 7.4 0.0048 17.7 0.0 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 ORY42752.1 - 0.002 17.5 0.4 0.011 15.1 0.0 2.3 3 0 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus ARGLU PF15346.6 ORY42752.1 - 0.0063 16.4 8.4 0.0063 16.4 8.4 4.3 5 0 0 5 5 5 1 Arginine and glutamate-rich 1 Nucleoporin_N PF08801.11 ORY42752.1 - 0.054 12.2 1.0 0.2 10.3 0.0 2.4 3 0 0 3 3 3 0 Nup133 N terminal like Phage_terminase PF10668.9 ORY42752.1 - 0.098 12.7 0.3 0.39 10.8 0.3 2.1 1 0 0 1 1 1 0 Phage terminase small subunit RXT2_N PF08595.11 ORY42752.1 - 2.8 7.9 9.0 3.1 7.8 3.3 3.1 3 0 0 3 3 3 0 RXT2-like, N-terminal ABC_membrane PF00664.23 ORY42753.1 - 6e-64 216.3 33.7 4.5e-34 118.4 14.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY42753.1 - 1e-57 194.5 0.0 1e-31 110.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 ORY42753.1 - 2.7e-08 33.9 2.1 0.00092 19.3 0.5 3.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY42753.1 - 1.5e-07 31.0 0.0 0.025 14.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 ORY42753.1 - 2.1e-07 31.7 3.5 0.036 14.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 ORY42753.1 - 3.2e-06 27.6 0.3 0.94 9.8 0.0 3.6 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.6 ORY42753.1 - 4.9e-06 26.6 0.7 0.15 11.8 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORY42753.1 - 1.3e-05 25.2 0.3 0.0058 16.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 ORY42753.1 - 1.9e-05 24.8 5.6 0.00013 22.0 0.0 3.4 4 0 0 4 4 4 1 Dynamin family SMC_N PF02463.19 ORY42753.1 - 2.6e-05 23.8 5.8 0.31 10.4 0.2 3.8 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 ORY42753.1 - 9.3e-05 21.8 0.2 0.18 11.1 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin DUF87 PF01935.17 ORY42753.1 - 0.00015 21.9 0.8 0.068 13.3 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_15 PF13175.6 ORY42753.1 - 0.00031 20.6 0.0 0.085 12.5 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 ORY42753.1 - 0.00047 19.6 0.2 0.08 12.3 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_7 PF12775.7 ORY42753.1 - 0.0011 18.6 0.3 0.63 9.5 0.1 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region NB-ARC PF00931.22 ORY42753.1 - 0.0013 17.9 0.5 1.6 7.9 0.1 2.7 3 0 0 3 3 3 2 NB-ARC domain T2SSE PF00437.20 ORY42753.1 - 0.0024 17.0 0.0 0.96 8.4 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.6 ORY42753.1 - 0.0025 18.1 0.1 2.1 8.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY42753.1 - 0.0036 17.0 0.1 1.8 8.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 ORY42753.1 - 0.012 15.4 0.1 0.74 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 ORY42753.1 - 0.021 13.7 0.2 6.8 5.4 0.0 3.2 4 0 0 4 4 4 0 Predicted ATPase of the ABC class cobW PF02492.19 ORY42753.1 - 0.035 13.7 2.4 1.6 8.3 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 ORY42753.1 - 0.036 14.3 1.5 4.2 7.6 0.1 3.3 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 ORY42753.1 - 0.059 12.9 0.0 12 5.3 0.0 2.6 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_25 PF13481.6 ORY42753.1 - 0.08 12.5 0.0 7.2 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 ORY42753.1 - 0.081 12.2 0.0 0.9 8.7 0.0 2.6 2 1 0 2 2 2 0 KAP family P-loop domain NACHT PF05729.12 ORY42753.1 - 0.096 12.6 0.3 2 8.3 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 ORY42753.1 - 0.22 12.1 0.6 8.2 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain AIG1 PF04548.16 ORY42753.1 - 0.52 9.6 4.9 2 7.7 0.0 2.8 3 0 0 3 3 3 0 AIG1 family MeaB PF03308.16 ORY42753.1 - 1.8 7.5 4.5 6 5.8 0.3 2.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TOM13 PF08219.11 ORY42754.1 - 0.078 13.0 0.0 0.094 12.7 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein TOM13 PALP PF00291.25 ORY42755.1 - 8.1e-66 222.4 0.1 1.2e-65 221.9 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 ORY42755.1 - 5.6e-09 36.3 0.0 3.1e-05 24.3 0.0 2.9 3 0 0 3 3 3 2 CBS domain LTV PF04180.14 ORY42756.1 - 1.4e-49 169.8 34.1 7e-43 147.8 29.0 4.1 1 1 2 3 3 3 2 Low temperature viability protein SAD_SRA PF02182.17 ORY42756.1 - 0.098 12.3 0.2 0.26 11.0 0.2 1.7 1 0 0 1 1 1 0 SAD/SRA domain YL1 PF05764.13 ORY42756.1 - 1 9.5 59.5 0.11 12.6 8.8 3.6 3 0 0 3 3 3 0 YL1 nuclear protein SDA1 PF05285.12 ORY42756.1 - 2 7.8 53.3 0.22 10.9 17.6 3.2 3 0 0 3 3 3 0 SDA1 zf-RanBP PF00641.18 ORY42757.1 - 2.3e-14 52.4 26.3 1.1e-07 31.0 2.1 3.4 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others Tom37 PF10568.9 ORY42758.1 - 0.077 13.3 0.3 0.077 13.3 0.3 1.8 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein Pertussis_S1 PF02917.14 ORY42758.1 - 0.26 11.0 3.3 0.42 10.4 3.3 1.2 1 0 0 1 1 1 0 Pertussis toxin, subunit 1 SHIPPO-rpt PF07004.12 ORY42759.1 - 0.03 15.2 1.3 11 7.2 0.1 3.5 3 0 0 3 3 3 0 Sperm-tail PG-rich repeat Pkinase PF00069.25 ORY42760.1 - 7.6e-58 195.9 0.0 1.4e-57 195.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY42760.1 - 1.9e-36 125.7 0.0 2.6e-26 92.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY42760.1 - 3.8e-07 29.7 0.0 5.9e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY42760.1 - 0.00022 20.2 0.0 0.00022 20.2 0.0 2.1 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 ORY42760.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family MIP-T3_C PF17749.1 ORY42761.1 - 0.00097 19.1 5.2 0.006 16.6 0.8 2.3 1 1 1 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region AIP3 PF03915.13 ORY42761.1 - 0.00099 18.3 8.8 0.0012 18.0 8.8 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 Fez1 PF06818.15 ORY42761.1 - 0.0039 17.7 6.8 0.0087 16.5 6.1 1.7 1 1 1 2 2 2 1 Fez1 BLOC1_2 PF10046.9 ORY42761.1 - 0.012 15.9 9.0 0.42 10.9 1.2 2.6 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rootletin PF15035.6 ORY42761.1 - 0.014 15.4 7.0 0.096 12.7 6.8 2.8 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.9 ORY42761.1 - 0.024 14.7 12.3 0.11 12.6 10.7 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF641 PF04859.12 ORY42761.1 - 0.036 14.4 9.3 0.19 12.1 1.0 3.1 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) Jnk-SapK_ap_N PF09744.9 ORY42761.1 - 0.041 14.1 1.6 0.041 14.1 1.6 2.3 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF4201 PF13870.6 ORY42761.1 - 0.054 13.2 4.9 0.16 11.7 1.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) HIP1_clath_bdg PF16515.5 ORY42761.1 - 0.059 14.0 12.6 1 10.0 2.7 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 ORY42761.1 - 0.16 10.8 12.2 0.85 8.4 2.4 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Mis12 PF05859.12 ORY42761.1 - 0.22 11.6 3.4 0.44 10.6 3.4 1.7 1 1 0 1 1 1 0 Mis12 protein DUF489 PF04356.12 ORY42761.1 - 0.28 11.2 5.2 4.9 7.1 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF489) ATG16 PF08614.11 ORY42761.1 - 0.3 11.3 11.1 0.035 14.3 5.2 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Csm1_N PF18504.1 ORY42761.1 - 0.36 11.2 9.8 0.44 10.9 0.1 3.7 2 2 2 4 4 4 0 Csm1 N-terminal domain FAM76 PF16046.5 ORY42761.1 - 0.43 9.9 4.5 0.32 10.3 2.6 1.6 1 1 0 1 1 1 0 FAM76 protein THOC7 PF05615.13 ORY42761.1 - 0.72 10.1 7.8 0.99 9.7 4.9 2.4 1 1 1 2 2 2 0 Tho complex subunit 7 DUF1664 PF07889.12 ORY42761.1 - 0.73 9.9 5.9 0.6 10.1 1.3 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DivIC PF04977.15 ORY42761.1 - 0.76 9.6 5.4 7.5 6.4 0.7 3.6 2 1 2 4 4 4 0 Septum formation initiator APG6_N PF17675.1 ORY42761.1 - 1.1 9.8 13.1 1 9.9 5.4 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region CENP-H PF05837.12 ORY42761.1 - 5.1 7.6 13.0 1.7 9.1 2.3 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) TMPIT PF07851.13 ORY42761.1 - 5.1 6.2 6.1 2.3 7.4 2.4 1.8 1 1 1 2 2 2 0 TMPIT-like protein Lectin_N PF03954.14 ORY42761.1 - 6 6.6 11.2 1.3 8.8 3.5 2.5 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Fib_alpha PF08702.10 ORY42761.1 - 7.6 6.7 9.2 28 4.9 3.7 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Ribosomal_L21e PF01157.18 ORY42762.1 - 3.2e-47 158.5 4.6 1.7e-46 156.2 3.4 1.9 2 0 0 2 2 2 1 Ribosomal protein L21e Ribosomal_S19e PF01090.19 ORY42763.1 - 7.8e-60 200.5 0.3 8.8e-60 200.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e MOZ_SAS PF01853.18 ORY42764.1 - 2.8e-82 274.7 0.1 3.9e-82 274.2 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 ORY42764.1 - 1.3e-21 76.0 4.9 1.3e-21 76.0 4.9 2.0 2 0 0 2 2 2 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 ORY42764.1 - 0.014 15.8 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PAP1 PF08601.10 ORY42764.1 - 0.041 13.6 1.3 0.065 13.0 1.3 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 tRNA_synt_1c_R2 PF04557.15 ORY42764.1 - 0.18 12.8 0.8 0.27 12.2 0.0 1.7 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 SelP_N PF04592.14 ORY42764.1 - 6.2 6.1 7.7 9.9 5.5 7.7 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region OSCP PF00213.18 ORY42765.1 - 1.3e-45 155.6 6.2 1.6e-45 155.3 6.2 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit IML1 PF12257.8 ORY42765.1 - 0.081 12.0 0.3 0.16 11.0 0.2 1.5 1 1 0 1 1 1 0 Vacuolar membrane-associated protein Iml1 UCH PF00443.29 ORY42766.1 - 2.5e-54 184.5 0.3 3e-54 184.2 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY42766.1 - 9.8e-22 78.0 0.4 1.3e-21 77.5 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-ribbon_3 PF13248.6 ORY42766.1 - 0.42 10.1 3.0 3 7.4 0.0 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-HIT PF04438.16 ORY42766.1 - 2.3 8.2 11.3 1.4 8.9 0.7 3.3 3 0 0 3 3 3 0 HIT zinc finger C1_2 PF03107.16 ORY42766.1 - 9 6.7 8.8 5.1 7.5 0.0 3.2 3 0 0 3 3 3 0 C1 domain Nucleoporin_N PF08801.11 ORY42767.1 - 6.8e-74 249.2 0.0 1.1e-73 248.5 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 ORY42767.1 - 1.7e-24 86.5 0.0 4.4e-24 85.2 0.0 1.6 1 1 1 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Sds3 PF08598.11 ORY42768.1 - 5.9e-05 23.2 29.8 5.9e-05 23.2 29.8 2.0 2 1 0 2 2 2 1 Sds3-like DIOX_N PF14226.6 ORY42769.1 - 0.00068 20.4 0.0 0.0011 19.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY42769.1 - 0.0033 17.9 0.0 0.0063 17.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AAA_12 PF13087.6 ORY42770.1 - 5.2e-54 182.9 0.0 1.3e-53 181.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORY42770.1 - 5.3e-35 121.5 4.8 5.5e-34 118.1 3.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY42770.1 - 8.1e-13 48.5 1.1 2.7e-06 27.3 0.3 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 ORY42770.1 - 2.8e-12 46.9 0.7 1.5e-06 28.2 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 ORY42770.1 - 3.5e-11 43.6 2.5 4.1e-10 40.2 2.5 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY42770.1 - 1.9e-05 25.1 0.1 0.00031 21.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.9 ORY42770.1 - 0.00023 20.5 0.0 0.18 11.0 0.0 2.7 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 ORY42770.1 - 0.00032 20.8 0.0 0.005 16.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY42770.1 - 0.00081 19.2 0.3 0.015 15.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 ORY42770.1 - 0.00091 18.8 0.0 0.25 10.8 0.0 2.4 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 ORY42770.1 - 0.0013 18.6 0.0 0.017 14.9 0.0 2.3 2 0 0 2 2 2 1 Helicase PhoH PF02562.16 ORY42770.1 - 0.007 15.8 0.6 2.7 7.4 0.1 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA PF00004.29 ORY42770.1 - 0.015 15.8 0.1 0.062 13.7 0.0 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.14 ORY42770.1 - 0.018 14.2 0.0 0.047 12.9 0.0 1.6 2 0 0 2 2 2 0 PIF1-like helicase FtsK_SpoIIIE PF01580.18 ORY42770.1 - 0.025 13.9 0.1 0.077 12.3 0.1 1.8 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.6 ORY42770.1 - 0.059 13.6 0.3 0.94 9.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORY42770.1 - 0.07 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region UvrD_C_2 PF13538.6 ORY42770.1 - 0.13 12.1 0.0 0.42 10.5 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Peptidase_S68 PF10461.9 ORY42770.1 - 0.41 10.9 2.2 1.6 9.0 2.2 2.1 1 0 0 1 1 1 0 Peptidase S68 DNA_pol_phi PF04931.13 ORY42770.1 - 1.2 7.2 4.9 1.8 6.6 4.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Ank_2 PF12796.7 ORY42772.1 - 0.0027 18.3 0.1 0.019 15.6 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY42772.1 - 0.0077 16.6 0.3 0.035 14.6 0.3 2.2 1 0 0 1 1 1 1 Ankyrin repeat MarR PF01047.22 ORY42772.1 - 0.11 12.5 0.1 0.29 11.1 0.1 1.7 1 0 0 1 1 1 0 MarR family Ank_5 PF13857.6 ORY42772.1 - 0.15 12.4 0.4 8.4 6.9 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY42772.1 - 0.39 11.4 3.1 2.9 8.7 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat MIP-T3_C PF17749.1 ORY42773.1 - 4.1e-40 137.3 11.4 4.1e-40 137.3 11.4 2.1 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region MIP-T3 PF10243.9 ORY42773.1 - 6.5e-37 126.0 0.3 1.3e-36 125.0 0.3 1.5 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CH-like domain TFIIA PF03153.13 ORY42773.1 - 0.26 11.2 27.2 0.086 12.8 24.5 1.5 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF641 PF04859.12 ORY42773.1 - 0.31 11.4 4.5 0.28 11.5 2.4 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) UPF0242 PF06785.11 ORY42773.1 - 0.74 9.9 11.8 0.064 13.4 6.6 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin PF02996.17 ORY42773.1 - 0.8 9.6 6.0 5.8 6.8 0.5 2.9 2 1 1 3 3 3 0 Prefoldin subunit KIAA1430 PF13879.6 ORY42774.1 - 2.7e-11 44.1 0.9 2.7e-11 44.1 0.9 2.5 2 0 0 2 2 2 1 KIAA1430 homologue AAA_16 PF13191.6 ORY42774.1 - 0.0097 16.3 0.0 0.078 13.4 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain SpoU_sub_bind PF08032.12 ORY42774.1 - 0.4 11.0 1.9 12 6.3 0.1 3.4 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding Armet PF10208.9 ORY42775.1 - 0.0023 17.9 1.3 0.0094 15.9 0.1 2.3 2 0 0 2 2 2 1 Degradation arginine-rich protein for mis-folding Nterm_IS4 PF13006.7 ORY42775.1 - 0.13 12.4 0.5 1.6 8.9 0.0 2.7 3 0 0 3 3 3 0 Insertion element 4 transposase N-terminal DUF2967 PF11179.8 ORY42775.1 - 0.22 9.6 14.3 0.3 9.2 14.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Lzipper-MIP1 PF14389.6 ORY42775.1 - 0.34 11.3 4.5 0.19 12.0 0.6 2.7 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 CCDC53 PF10152.9 ORY42775.1 - 1.9 8.9 7.0 4.6 7.6 7.0 1.7 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex RNA_pol_3_Rpc31 PF11705.8 ORY42776.1 - 1.2e-13 51.8 18.5 2e-13 51.1 18.5 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.11 ORY42776.1 - 0.047 13.3 6.8 0.052 13.1 6.8 1.1 1 0 0 1 1 1 0 PPP4R2 CTF_NFI PF00859.18 ORY42776.1 - 0.15 11.9 0.3 0.25 11.2 0.2 1.3 1 1 0 1 1 1 0 CTF/NF-I family transcription modulation region NOA36 PF06524.12 ORY42776.1 - 1.8 7.8 9.2 2 7.7 9.2 1.1 1 0 0 1 1 1 0 NOA36 protein HSP70 PF00012.20 ORY42777.1 - 9.1e-118 394.0 6.8 1.1e-117 393.8 6.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY42777.1 - 1.4e-11 43.9 0.1 3.2e-11 42.6 0.1 1.6 1 0 0 1 1 1 1 MreB/Mbl protein DUF3403 PF11883.8 ORY42777.1 - 0.059 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3403) Ribonuc_L-PSP PF01042.21 ORY42778.1 - 6.2e-46 155.4 0.5 6.9e-46 155.2 0.5 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Mt_ATP-synt_D PF05873.12 ORY42778.1 - 0.024 14.5 0.0 0.032 14.1 0.0 1.1 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) RPN1_RPN2_N PF17781.1 ORY42778.1 - 0.094 12.1 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain YjgF_endoribonc PF14588.6 ORY42778.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease Ribonuc_L-PSP PF01042.21 ORY42779.1 - 1.2e-45 154.5 0.3 1.3e-45 154.3 0.3 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Mt_ATP-synt_D PF05873.12 ORY42779.1 - 0.022 14.6 0.0 0.029 14.2 0.0 1.1 1 0 0 1 1 1 0 ATP synthase D chain, mitochondrial (ATP5H) RPN1_RPN2_N PF17781.1 ORY42779.1 - 0.093 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain YjgF_endoribonc PF14588.6 ORY42779.1 - 0.13 12.4 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 YjgF/chorismate_mutase-like, putative endoribonuclease FoP_duplication PF13865.6 ORY42780.1 - 0.036 14.6 11.6 0.055 14.0 11.6 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 ubiquitin PF00240.23 ORY42781.1 - 9e-05 22.2 0.0 0.0016 18.2 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin family LCE PF14672.6 ORY42781.1 - 0.16 12.6 1.5 0.74 10.5 1.5 2.2 1 0 0 1 1 1 0 Late cornified envelope Malate_synthase PF01274.22 ORY42782.1 - 1.7e-216 719.6 0.0 1.9e-216 719.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Choline_kinase PF01633.20 ORY42783.1 - 4.3e-58 196.4 0.0 1.2e-57 194.9 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 ORY42783.1 - 3.8e-08 33.6 0.0 6.6e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ORY42783.1 - 0.02 14.2 0.2 0.1 11.9 0.2 2.0 1 1 0 1 1 1 0 Ecdysteroid kinase Hus1 PF04005.12 ORY42784.1 - 1.3e-63 214.9 0.0 1.5e-63 214.6 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein FoP_duplication PF13865.6 ORY42786.1 - 0.036 14.6 11.6 0.055 14.0 11.6 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 ubiquitin PF00240.23 ORY42787.1 - 7.3e-05 22.4 0.0 0.0016 18.2 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin family LCE PF14672.6 ORY42787.1 - 1.4 9.6 5.2 0.74 10.5 1.5 2.5 2 0 0 2 2 2 0 Late cornified envelope DIOX_N PF14226.6 ORY42788.1 - 0.00021 22.0 0.0 0.00033 21.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Peptidase_S68 PF10461.9 ORY42789.1 - 0.11 12.7 1.4 0.29 11.4 1.4 1.7 1 0 0 1 1 1 0 Peptidase S68 AAA_12 PF13087.6 ORY42790.1 - 2.1e-54 184.2 0.0 5.8e-54 182.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 ORY42790.1 - 5e-24 85.5 2.6 1e-22 81.2 1.3 2.9 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 ORY42790.1 - 1.9e-11 44.2 0.1 7.3e-07 29.2 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 ORY42790.1 - 9.2e-05 22.2 0.3 0.00035 20.4 0.3 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY42790.1 - 0.0033 17.8 0.9 0.029 14.7 0.9 2.3 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 ORY42790.1 - 0.067 13.0 0.0 0.24 11.3 0.0 2.0 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DNA_pol_phi PF04931.13 ORY42790.1 - 0.75 7.8 5.1 1.1 7.3 5.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi mRNA_triPase PF02940.15 ORY42792.1 - 1.4e-45 155.7 7.1 1e-32 113.6 2.0 2.1 1 1 1 2 2 2 2 mRNA capping enzyme, beta chain Ribosomal_L21e PF01157.18 ORY42793.1 - 3.2e-47 158.5 4.6 1.7e-46 156.2 3.4 1.9 2 0 0 2 2 2 1 Ribosomal protein L21e WD40 PF00400.32 ORY42794.1 - 1.9e-41 139.3 12.1 9.7e-07 29.4 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY42794.1 - 2e-14 53.7 0.1 0.001 19.3 0.0 5.8 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY42794.1 - 1.8e-07 30.8 1.8 0.0067 15.8 0.2 3.4 2 2 2 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 ORY42794.1 - 9.6e-06 24.8 2.0 0.023 13.6 0.0 4.2 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5046 PF16465.5 ORY42794.1 - 0.00022 20.8 1.0 0.54 9.7 0.0 3.1 2 1 2 4 4 4 2 Domain of unknown function (DUF5046) Nup160 PF11715.8 ORY42794.1 - 0.0004 19.2 0.3 2.3 6.8 0.1 4.0 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Frtz PF11768.8 ORY42794.1 - 0.033 12.5 0.0 1 7.6 0.0 2.3 1 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz BBS2_Mid PF14783.6 ORY42794.1 - 0.055 13.5 0.2 16 5.6 0.0 3.4 2 2 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF2745 PF10922.8 ORY42794.1 - 0.16 12.2 0.8 2.3 8.6 0.0 2.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2745) PQQ_3 PF13570.6 ORY42794.1 - 0.25 11.9 5.0 5.1 7.7 0.0 4.4 5 0 0 5 5 5 0 PQQ-like domain RRM_1 PF00076.22 ORY42795.1 - 4.5e-33 112.9 0.4 9.3e-17 60.6 0.0 4.6 3 2 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY42795.1 - 9.8e-07 28.8 0.0 0.022 14.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 ORY42795.1 - 0.019 14.8 0.0 12 5.9 0.0 3.3 3 0 0 3 3 3 0 Occluded RNA-recognition motif E1-E2_ATPase PF00122.20 ORY42796.1 - 4.1e-45 153.5 1.9 4.1e-45 153.5 1.9 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORY42796.1 - 1e-42 146.8 0.7 1e-42 146.8 0.7 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 ORY42796.1 - 1.1e-29 102.6 0.8 7.4e-13 48.7 0.0 3.6 3 0 0 3 3 3 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 ORY42796.1 - 0.00072 19.4 1.1 0.043 13.6 0.8 2.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase WD40 PF00400.32 ORY42797.1 - 2.8e-30 103.9 25.6 3.4e-05 24.5 0.0 10.4 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY42797.1 - 2.1e-11 43.9 0.6 0.00014 22.0 0.0 6.8 4 2 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY42797.1 - 1.9e-07 30.1 0.5 0.12 11.0 0.0 5.2 4 2 2 6 6 6 2 Nucleoporin Nup120/160 EF-hand_8 PF13833.6 ORY42797.1 - 1.5e-05 24.8 2.2 3.6e-05 23.5 1.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 ORY42797.1 - 3e-05 24.4 0.7 0.00017 21.9 0.7 2.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 ORY42797.1 - 0.0002 20.7 0.0 0.00051 19.4 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 ORY42797.1 - 0.00021 20.6 0.2 0.00075 18.9 0.2 2.1 1 0 0 1 1 1 1 EF hand eIF2A PF08662.11 ORY42797.1 - 0.00045 20.1 1.0 0.088 12.7 0.0 3.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A EF-hand_6 PF13405.6 ORY42797.1 - 0.0068 16.3 0.6 0.03 14.2 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain Nucleoporin_N PF08801.11 ORY42797.1 - 0.024 13.4 3.9 3.5 6.3 0.0 3.8 3 1 2 5 5 5 0 Nup133 N terminal like ubiquitin PF00240.23 ORY42798.1 - 3.5e-27 94.0 0.0 3.8e-27 93.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY42798.1 - 2.5e-15 56.1 0.0 2.7e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORY42798.1 - 6e-05 23.4 0.0 0.00016 22.1 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 ORY42798.1 - 6.4e-05 22.8 0.0 7.5e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_4 PF18036.1 ORY42798.1 - 0.022 14.8 0.1 0.53 10.4 0.2 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain HATPase_c PF02518.26 ORY42798.1 - 0.041 14.4 0.0 0.048 14.2 0.0 1.1 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Rad60-SLD_2 PF13881.6 ORY42798.1 - 0.064 13.4 0.0 0.16 12.1 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Pkinase PF00069.25 ORY42799.1 - 4.5e-73 245.8 0.0 6.2e-73 245.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY42799.1 - 1.4e-44 152.4 0.0 1.9e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY42799.1 - 6.2e-06 25.2 0.0 6.2e-06 25.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 ORY42799.1 - 0.00018 21.2 0.0 0.00051 19.7 0.0 1.7 1 1 1 2 2 2 1 RIO1 family Kinase-like PF14531.6 ORY42799.1 - 0.004 16.5 0.0 0.0063 15.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY42799.1 - 0.031 14.2 0.0 0.083 12.8 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY42799.1 - 0.044 12.7 0.1 0.075 12.0 0.1 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Plk4_PB1 PF18190.1 ORY42799.1 - 0.046 13.9 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 Polo-like Kinase 4 Polo Box 1 Kdo PF06293.14 ORY42799.1 - 0.064 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NUDIX_4 PF14815.6 ORY42799.1 - 0.073 13.1 0.1 0.22 11.5 0.1 1.7 1 0 0 1 1 1 0 NUDIX domain Glycos_trans_3N PF02885.17 ORY42799.1 - 0.075 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain DUF3915 PF13054.6 ORY42799.1 - 0.15 12.0 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) POLO_box PF00659.18 ORY42799.1 - 0.51 10.6 2.5 12 6.2 0.0 3.3 3 1 0 3 3 3 0 POLO box duplicated region FAM27 PF15832.5 ORY42799.1 - 0.64 10.6 6.9 1.7 9.3 5.8 2.2 2 0 0 2 2 2 0 FAM27 D and E protein family RRM_1 PF00076.22 ORY42800.1 - 2.6e-20 72.0 0.0 1.4e-10 40.9 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY42800.1 - 1.1e-08 34.8 0.0 0.0014 18.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PPP4R2 PF09184.11 ORY42800.1 - 0.0028 17.3 0.4 0.0032 17.1 0.4 1.1 1 0 0 1 1 1 1 PPP4R2 TFIIA PF03153.13 ORY42800.1 - 0.029 14.4 2.8 0.034 14.2 2.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CPSF100_C PF13299.6 ORY42800.1 - 0.08 13.1 1.0 0.12 12.5 1.0 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DNA_pol_phi PF04931.13 ORY42800.1 - 0.098 10.8 6.9 0.13 10.4 6.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_3_Rpc31 PF11705.8 ORY42800.1 - 0.3 11.3 8.8 0.43 10.8 8.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FYDLN_acid PF09538.10 ORY42800.1 - 0.44 11.3 11.5 0.69 10.6 11.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) UPF0560 PF10577.9 ORY42800.1 - 0.56 8.7 4.8 0.72 8.3 4.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Cwf_Cwc_15 PF04889.12 ORY42800.1 - 1.1 8.9 10.8 1.6 8.4 10.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein EBV-NA3 PF05009.12 ORY42800.1 - 1.1 8.7 3.2 1.6 8.2 3.2 1.3 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) NOA36 PF06524.12 ORY42800.1 - 5 6.4 9.3 7.2 5.8 9.3 1.2 1 0 0 1 1 1 0 NOA36 protein Ribosomal_S13 PF00416.22 ORY42801.1 - 1.4e-20 74.0 0.0 2.4e-18 66.8 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 HHH_5 PF14520.6 ORY42801.1 - 0.04 14.5 0.0 0.14 12.8 0.0 2.0 2 1 0 2 2 2 0 Helix-hairpin-helix domain DAO PF01266.24 ORY42802.1 - 5e-44 151.3 0.1 5.9e-44 151.1 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY42802.1 - 4.6e-05 23.6 0.1 9.6e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY42802.1 - 0.001 18.3 0.0 0.014 14.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY42802.1 - 0.0013 17.9 1.1 0.028 13.5 1.1 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 ORY42802.1 - 0.0038 17.2 0.2 1.6 8.7 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 ORY42802.1 - 0.015 14.2 0.3 0.02 13.7 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 ORY42802.1 - 0.098 13.2 0.2 0.22 12.1 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY42802.1 - 0.13 11.5 0.0 0.85 8.8 0.0 2.0 2 0 0 2 2 2 0 Thi4 family MDD_C PF18376.1 ORY42803.1 - 2.4e-72 242.6 0.1 3.4e-72 242.1 0.1 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 ORY42803.1 - 1.1e-05 25.6 3.6 3.2e-05 24.1 3.6 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain Tyrosinase PF00264.20 ORY42804.1 - 1.6e-32 113.6 20.9 8.4e-31 108.0 11.8 2.2 2 0 0 2 2 2 2 Common central domain of tyrosinase KRAB PF01352.27 ORY42804.1 - 0.15 11.8 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 KRAB box Tyrosinase PF00264.20 ORY42805.1 - 2e-26 93.7 8.8 2e-26 93.7 8.8 2.3 2 0 0 2 2 2 1 Common central domain of tyrosinase FSA_C PF10479.9 ORY42805.1 - 5.1 5.1 14.6 7.9 4.5 14.6 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Glyco_hydro_18 PF00704.28 ORY42806.1 - 2.5e-66 224.6 5.0 3.3e-66 224.1 5.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ABC_tran PF00005.27 ORY42807.1 - 4.4e-36 124.4 0.0 7.9e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ORY42807.1 - 1e-34 120.4 8.8 1.4e-34 120.0 8.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ORY42807.1 - 2.6e-08 33.6 0.2 3.1e-05 23.5 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY42807.1 - 0.00041 20.8 0.1 0.00098 19.5 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ORY42807.1 - 0.00075 19.2 2.3 0.0045 16.7 0.1 2.9 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_22 PF13401.6 ORY42807.1 - 0.001 19.4 0.1 0.02 15.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 ORY42807.1 - 0.0017 18.4 0.0 0.0042 17.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY42807.1 - 0.0043 17.0 0.0 0.013 15.4 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 ORY42807.1 - 0.0056 16.0 0.1 0.029 13.7 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_21 PF13304.6 ORY42807.1 - 0.011 15.5 0.1 0.038 13.8 0.0 1.9 3 0 0 3 3 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 ORY42807.1 - 0.03 14.3 0.3 4.1 7.4 0.0 2.9 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 ORY42807.1 - 0.051 12.7 0.0 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit SbcCD_C PF13558.6 ORY42807.1 - 0.066 13.5 0.3 1.5 9.1 0.3 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 ORY42807.1 - 0.089 12.5 0.1 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain DUF3987 PF13148.6 ORY42807.1 - 0.096 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_23 PF13476.6 ORY42807.1 - 0.17 12.4 0.0 0.37 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain MpPF26 PF07666.11 ORY42807.1 - 9.2 6.4 8.8 0.33 11.1 2.4 1.8 2 0 0 2 2 1 0 M penetrans paralogue family 26 Tyrosinase PF00264.20 ORY42808.1 - 9.5e-30 104.5 0.3 9.5e-30 104.5 0.3 2.3 2 0 0 2 2 2 1 Common central domain of tyrosinase Adaptin_N PF01602.20 ORY42809.1 - 5.5e-125 417.9 0.6 6.5e-125 417.6 0.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 ORY42809.1 - 1.6e-19 70.3 0.0 3.9e-19 69.0 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 ORY42809.1 - 8.9e-09 35.6 1.5 1.2e-05 25.5 0.0 2.7 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORY42809.1 - 0.041 14.1 0.1 61 4.3 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat Peptidase_M73 PF12389.8 ORY42809.1 - 0.055 13.3 0.3 0.098 12.5 0.3 1.3 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase Arm PF00514.23 ORY42809.1 - 0.086 12.9 1.2 22 5.3 0.0 4.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Glyco_hydro_4C PF11975.8 ORY42809.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain Hexokinase_2 PF03727.16 ORY42810.1 - 7.7e-83 277.6 0.1 1.2e-82 277.0 0.1 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORY42810.1 - 3e-69 232.9 0.3 4.3e-69 232.4 0.3 1.2 1 0 0 1 1 1 1 Hexokinase Ribosomal_L7Ae PF01248.26 ORY42811.1 - 2.1e-23 81.9 0.0 2.6e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Clathrin_lg_ch PF01086.17 ORY42812.1 - 2.7e-36 125.8 15.8 1.7e-35 123.2 15.8 1.9 1 1 0 1 1 1 1 Clathrin light chain DUF1464 PF07318.12 ORY42812.1 - 0.065 12.4 0.1 0.084 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) ArAE_2_N PF10337.9 ORY42812.1 - 0.14 11.1 0.3 0.2 10.6 0.3 1.2 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Phage_SSB PF16773.5 ORY42812.1 - 0.4 10.8 0.2 0.4 10.8 0.2 2.3 3 0 0 3 3 3 0 Lactococcus phage single-stranded DNA binding protein TPR_19 PF14559.6 ORY42813.1 - 4.7e-18 65.5 7.8 1.1e-05 25.9 0.1 6.4 5 2 1 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY42813.1 - 4.1e-14 52.6 20.1 0.00063 19.9 0.5 5.1 4 1 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 ORY42813.1 - 6.1e-10 38.4 19.7 0.36 11.1 0.1 8.6 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORY42813.1 - 2.9e-07 30.8 0.4 0.78 10.7 0.0 6.5 6 2 2 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY42813.1 - 4.9e-06 26.8 10.9 0.63 10.8 0.0 6.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY42813.1 - 0.00016 21.9 12.4 1.2 9.5 0.1 6.9 6 2 0 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORY42813.1 - 0.00017 21.7 0.0 1.1 9.5 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY42813.1 - 0.00045 20.1 8.0 0.15 12.2 0.2 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat Coatomer_E PF04733.14 ORY42813.1 - 0.0012 18.3 1.0 0.018 14.4 0.3 2.3 2 0 0 2 2 2 1 Coatomer epsilon subunit TPR_16 PF13432.6 ORY42813.1 - 0.0023 18.6 0.0 14 6.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY42813.1 - 0.003 17.7 11.8 6.1 7.3 0.1 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY42813.1 - 0.018 14.9 26.1 0.51 10.2 0.1 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat PPR PF01535.20 ORY42813.1 - 0.029 14.6 4.7 8.9 6.8 0.0 5.3 6 0 0 6 6 5 0 PPR repeat Fis1_TPR_C PF14853.6 ORY42813.1 - 0.32 11.1 6.1 6.8 6.8 0.1 4.5 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 ORY42813.1 - 2.1 8.9 4.3 3.4 8.3 0.1 3.7 4 1 1 5 5 4 0 Tetratricopeptide repeat Kinesin PF00225.23 ORY42814.1 - 2.2e-20 72.9 1.8 2.2e-20 72.9 1.8 2.8 2 2 1 3 3 3 1 Kinesin motor domain DUF4472 PF14739.6 ORY42814.1 - 1.2e-05 26.0 18.2 1.2e-05 26.0 18.2 5.3 3 1 1 5 5 5 1 Domain of unknown function (DUF4472) DUF2968 PF11180.8 ORY42814.1 - 0.002 17.8 5.6 0.002 17.8 5.6 3.9 3 1 0 4 4 4 1 Protein of unknown function (DUF2968) CENP-F_leu_zip PF10473.9 ORY42814.1 - 0.0024 17.9 25.6 0.0024 17.9 25.6 4.1 2 1 2 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF737 PF05300.11 ORY42814.1 - 0.0077 16.6 2.7 0.0077 16.6 2.7 3.9 2 1 2 4 4 4 1 Protein of unknown function (DUF737) Metal_resist PF13801.6 ORY42814.1 - 0.015 15.5 3.7 1.2 9.3 0.4 2.7 2 0 0 2 2 2 0 Heavy-metal resistance ATG16 PF08614.11 ORY42814.1 - 0.022 15.0 59.8 0.21 11.8 26.2 4.1 1 1 1 3 3 3 0 Autophagy protein 16 (ATG16) MAD PF05557.13 ORY42814.1 - 0.97 7.7 66.0 2.2 6.6 36.3 2.5 1 1 1 2 2 2 0 Mitotic checkpoint protein CCDC92 PF14916.6 ORY42814.1 - 6 6.7 18.4 2.4 8.0 0.8 5.0 4 1 1 5 5 5 0 Coiled-coil domain of unknown function WD40 PF00400.32 ORY42815.1 - 9.7e-21 73.7 6.2 3.6e-05 24.4 0.1 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY42815.1 - 3.9e-06 27.1 0.0 1.1 9.7 0.0 4.9 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY42815.1 - 0.00027 20.0 0.0 0.0047 15.9 0.0 2.6 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORY42815.1 - 0.0012 18.8 1.2 5.4 6.8 0.0 3.4 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.9 ORY42815.1 - 0.13 12.0 0.0 3 7.6 0.0 2.7 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Nop14 PF04147.12 ORY42815.1 - 1.2 7.2 9.9 2.1 6.5 9.9 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 ORY42815.1 - 1.7 6.7 13.6 2.6 6.0 13.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi HNF-1_N PF04814.13 ORY42815.1 - 4.7 7.8 6.7 3.2 8.3 4.3 1.8 1 1 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus PPP4R2 PF09184.11 ORY42815.1 - 6 6.4 12.3 15 5.1 12.3 1.6 1 0 0 1 1 1 0 PPP4R2 RNA_pol_Rpb6 PF01192.22 ORY42816.1 - 3.6e-17 62.0 0.0 6.4e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 IBR PF01485.21 ORY42817.1 - 8.6e-08 32.3 24.5 1.6e-05 25.0 7.0 3.6 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain TFIIA PF03153.13 ORY42817.1 - 0.0052 16.8 45.2 0.16 11.9 2.9 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Focadhesin PF11229.8 ORY42817.1 - 0.044 12.0 0.0 0.071 11.3 0.0 1.2 1 0 0 1 1 1 0 Focadhesin WD40 PF00400.32 ORY42818.1 - 3.6e-36 122.6 22.5 1.4e-06 28.9 0.1 8.1 7 1 0 7 7 7 7 WD domain, G-beta repeat PQQ_3 PF13570.6 ORY42818.1 - 9.5e-08 32.3 1.3 0.44 11.1 0.1 5.8 4 1 1 5 5 5 3 PQQ-like domain Nup160 PF11715.8 ORY42818.1 - 5.4e-05 22.0 1.0 0.17 10.5 0.0 4.2 3 1 0 5 5 5 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 ORY42818.1 - 0.00026 21.2 0.4 13 6.2 0.0 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY42818.1 - 0.00043 19.7 0.1 0.0012 18.2 0.0 1.7 1 1 0 1 1 1 1 WD40-like domain PQQ PF01011.21 ORY42818.1 - 0.046 13.7 1.1 4.1 7.5 0.0 4.0 5 0 0 5 5 5 0 PQQ enzyme repeat Peptidase_C9 PF01707.16 ORY42818.1 - 0.049 13.2 0.1 10 5.6 0.1 2.5 2 0 0 2 2 2 0 Peptidase family C9 Actin PF00022.19 ORY42819.1 - 2.6e-115 385.3 0.0 2.4e-114 382.1 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 ORY42819.1 - 0.0038 16.1 0.0 0.0097 14.8 0.0 1.5 1 1 0 1 1 1 1 MreB/Mbl protein DUF3502 PF12010.8 ORY42819.1 - 0.011 16.3 0.0 0.63 10.7 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3502) Actin_micro PF17003.5 ORY42819.1 - 0.29 10.3 0.5 16 4.5 0.2 2.3 2 0 0 2 2 2 0 Putative actin-like family RNase_H2_suC PF08615.11 ORY42820.1 - 2.6e-16 60.1 0.0 1.9e-09 37.8 0.0 2.1 1 1 1 2 2 2 2 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) SH3_1 PF00018.28 ORY42821.1 - 3e-14 52.3 3.4 1.8e-09 37.0 0.0 2.9 2 1 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 ORY42821.1 - 4e-11 42.6 0.1 1.1e-05 25.2 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 ORY42821.1 - 7.7e-11 41.5 1.3 8.8e-07 28.5 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain RA PF00788.23 ORY42821.1 - 1.8e-08 34.9 0.0 3.1e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_3 PF08239.11 ORY42821.1 - 9e-06 25.9 9.8 0.028 14.7 0.3 3.4 3 0 0 3 3 3 2 Bacterial SH3 domain SH3_4 PF06347.13 ORY42821.1 - 0.15 11.9 2.7 4.7 7.1 0.2 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain YfkD PF14167.6 ORY42821.1 - 0.23 10.6 0.3 0.79 8.9 0.0 1.8 2 0 0 2 2 2 0 YfkD-like protein Ribosomal_L21p PF00829.21 ORY42822.1 - 8.8e-14 51.6 0.2 1e-13 51.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein zf-RING_2 PF13639.6 ORY42823.1 - 1.1e-14 54.4 26.6 7.9e-09 35.7 10.3 3.3 2 1 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.6 ORY42823.1 - 1.2e-12 47.6 21.8 4.1e-06 26.7 3.8 2.8 2 1 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY42823.1 - 5.7e-12 45.3 23.5 6e-06 26.0 11.2 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY42823.1 - 1.1e-10 41.1 19.8 1.1e-05 25.1 8.5 3.7 3 0 0 3 3 3 3 RING-like zinc finger zf-RING_UBOX PF13445.6 ORY42823.1 - 4.1e-10 39.5 18.3 1.1e-05 25.4 7.4 3.7 2 1 1 3 3 3 2 RING-type zinc-finger zf-rbx1 PF12678.7 ORY42823.1 - 1.3e-08 35.0 19.1 2.3e-05 24.6 8.4 3.0 2 1 0 2 2 2 2 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 ORY42823.1 - 1.7e-08 34.1 22.8 8.7e-05 22.3 0.9 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORY42823.1 - 1.3e-07 31.5 10.7 3.2e-05 23.9 2.0 3.0 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 ORY42823.1 - 3.9e-06 26.6 26.8 6.4e-06 25.9 8.9 3.8 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) IQ PF00612.27 ORY42823.1 - 1.8e-05 24.2 0.1 6.5e-05 22.4 0.1 2.1 1 0 0 1 1 1 1 IQ calmodulin-binding motif Prok-RING_4 PF14447.6 ORY42823.1 - 0.00012 21.9 19.9 0.0016 18.2 0.2 2.9 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 ORY42823.1 - 0.00077 19.0 19.9 0.0012 18.4 5.9 3.0 3 1 0 3 3 3 2 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 ORY42823.1 - 0.00084 19.1 12.1 0.2 11.5 0.2 2.6 2 0 0 2 2 2 2 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 ORY42823.1 - 0.014 15.7 3.6 0.014 15.7 3.6 3.1 3 0 0 3 3 3 0 RING-like domain zf-C3H2C3 PF17122.5 ORY42823.1 - 0.042 13.9 14.9 1.9 8.6 0.1 3.6 3 1 0 3 3 3 0 Zinc-finger zf-Nse PF11789.8 ORY42823.1 - 0.17 11.7 13.3 0.031 14.1 6.4 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Pellino PF04710.14 ORY42823.1 - 0.62 8.7 5.9 7.8 5.0 1.2 2.6 2 1 1 3 3 3 0 Pellino FYVE_2 PF02318.16 ORY42823.1 - 1.5 9.1 16.2 0.054 13.7 3.7 2.8 3 0 0 3 3 3 0 FYVE-type zinc finger HscB_4_cys PF18256.1 ORY42823.1 - 3 7.7 8.0 1.1 9.1 0.4 2.8 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif DUF1752 PF08550.10 ORY42824.1 - 1.6e-07 31.0 5.2 3.4e-07 30.0 5.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) S4 PF01479.25 ORY42825.1 - 3.6e-12 45.8 1.0 3.6e-12 45.8 1.0 1.9 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 ORY42825.1 - 0.00022 22.0 0.3 0.00059 20.7 0.1 1.9 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Topoisom_bac PF01131.20 ORY42826.1 - 6.3e-104 348.3 0.0 7.7e-104 348.0 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 ORY42826.1 - 1.1e-19 70.6 0.0 2.4e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Toprim domain ERCC4 PF02732.15 ORY42827.1 - 2.8e-24 86.1 0.0 5.2e-24 85.2 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 ORY42827.1 - 0.00054 20.3 0.1 0.0027 18.1 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain DUF2816 PF10992.8 ORY42827.1 - 0.088 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2816) Spa1_C PF18218.1 ORY42827.1 - 0.13 12.7 0.0 1.1 9.8 0.0 2.5 2 0 0 2 2 2 0 Lantibiotic immunity protein Spa1 C-terminal domain DUF1869 PF08956.10 ORY42827.1 - 0.14 12.1 0.1 3.5 7.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) ABC2_membrane PF01061.24 ORY42828.1 - 4.6e-36 124.2 18.5 4.6e-36 124.2 18.5 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 ORY42828.1 - 1.4e-27 96.9 0.0 2.1e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 ORY42828.1 - 1.4e-05 25.1 0.1 2.7e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 ORY42828.1 - 0.0004 20.8 0.0 0.00062 20.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain MMR_HSR1 PF01926.23 ORY42828.1 - 0.0018 18.3 0.1 0.004 17.2 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_25 PF13481.6 ORY42828.1 - 0.007 16.0 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORY42828.1 - 0.008 15.9 0.2 0.016 14.9 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.6 ORY42828.1 - 0.0082 16.4 0.0 0.013 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY42828.1 - 0.012 15.9 0.1 0.029 14.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 ORY42828.1 - 0.018 14.0 0.1 0.037 13.0 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 ORY42828.1 - 0.028 14.3 0.4 0.099 12.5 0.2 2.0 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.19 ORY42828.1 - 0.04 13.3 0.1 0.13 11.7 0.1 1.7 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 ORY42828.1 - 0.043 13.5 0.2 0.07 12.8 0.2 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY42828.1 - 0.059 13.8 0.0 0.19 12.1 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_21 PF13304.6 ORY42828.1 - 0.062 13.1 0.0 9.9 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF2075 PF09848.9 ORY42828.1 - 0.067 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Dynamin_N PF00350.23 ORY42828.1 - 0.12 12.5 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Dynamin family T2SSE PF00437.20 ORY42828.1 - 0.15 11.1 0.1 0.24 10.4 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_ATPase PF09818.9 ORY42828.1 - 0.2 10.4 0.1 0.32 9.7 0.1 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_24 PF13479.6 ORY42828.1 - 0.21 11.3 0.1 0.36 10.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ORY42828.1 - 0.22 11.3 0.1 0.43 10.3 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF87 PF01935.17 ORY42828.1 - 0.26 11.4 0.3 0.54 10.3 0.3 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain Zeta_toxin PF06414.12 ORY42828.1 - 0.27 10.5 0.2 0.4 9.9 0.2 1.2 1 0 0 1 1 1 0 Zeta toxin Methyltransf_23 PF13489.6 ORY42829.1 - 0.0049 16.7 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORY42829.1 - 0.011 15.5 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 ORY42829.1 - 0.039 13.8 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Transketolase_C PF02780.20 ORY42829.1 - 0.12 12.2 0.0 0.79 9.6 0.0 2.0 2 0 0 2 2 2 0 Transketolase, C-terminal domain tRNA-synt_2 PF00152.20 ORY42830.1 - 2.2e-75 253.6 1.2 3.1e-75 253.2 1.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORY42830.1 - 3.7e-08 33.2 0.1 7.2e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain AUX_IAA PF02309.16 ORY42830.1 - 0.0059 16.5 0.6 0.034 14.0 0.0 2.2 2 0 0 2 2 2 1 AUX/IAA family tRNA-synt_2d PF01409.20 ORY42830.1 - 0.15 11.5 2.0 9.5 5.6 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class II core domain (F) Erythro_esteras PF05139.14 ORY42830.1 - 0.56 10.0 3.3 53 3.5 1.0 3.0 2 1 1 3 3 3 0 Erythromycin esterase NUDIX PF00293.28 ORY42831.1 - 9.6e-08 32.1 0.0 0.00012 22.1 0.0 2.9 1 1 1 2 2 2 2 NUDIX domain EMC1_C PF07774.13 ORY42831.1 - 0.024 14.3 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 ER membrane protein complex subunit 1, C-terminal Abhydrolase_6 PF12697.7 ORY42833.1 - 2.4e-14 54.5 0.0 4.1e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY42833.1 - 2.8e-11 43.1 0.0 2.7e-09 36.7 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY42833.1 - 9.4e-11 41.8 0.1 9.9e-10 38.5 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1749 PF08538.10 ORY42833.1 - 0.00032 19.9 0.0 0.00074 18.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF676 PF05057.14 ORY42833.1 - 0.0046 16.5 0.0 0.011 15.3 0.0 1.6 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.13 ORY42833.1 - 0.0071 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.22 ORY42833.1 - 0.02 14.8 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Cutinase LIDHydrolase PF10230.9 ORY42833.1 - 0.028 14.0 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase VirJ PF06057.11 ORY42833.1 - 0.033 14.1 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Peptidase_S9 PF00326.21 ORY42833.1 - 0.092 12.2 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 ORY42833.1 - 0.66 9.7 3.6 0.75 9.5 0.1 2.4 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Rhodanese PF00581.20 ORY42834.1 - 1.9e-18 66.9 0.0 1.6e-09 38.3 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain GCFC PF07842.12 ORY42836.1 - 0.0017 18.0 1.4 0.31 10.6 0.0 2.4 2 1 0 2 2 2 2 GC-rich sequence DNA-binding factor-like protein SBD_N PF07005.11 ORY42837.1 - 0.039 13.7 0.0 0.042 13.6 0.0 1.0 1 0 0 1 1 1 0 Sugar-binding N-terminal domain HSD3 PF15244.6 ORY42837.1 - 0.084 12.4 1.9 0.091 12.3 1.9 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 FBPase_glpX PF03320.13 ORY42837.1 - 0.21 10.4 0.2 0.24 10.2 0.2 1.1 1 0 0 1 1 1 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded CAP_N PF01213.19 ORY42838.1 - 0.48 9.9 4.2 0.95 8.9 4.2 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal GCFC PF07842.12 ORY42839.1 - 6.8e-09 35.7 1.1 5e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 GC-rich sequence DNA-binding factor-like protein CAP_C PF08603.11 ORY42840.1 - 2.2e-09 37.1 1.1 2.9e-09 36.7 1.1 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 ORY42840.1 - 0.001 18.8 1.8 0.013 15.2 0.8 2.3 1 1 1 2 2 2 2 Tubulin binding cofactor C PFK PF00365.20 ORY42841.1 - 8.3e-179 593.0 0.1 4.7e-94 314.9 0.0 2.1 2 0 0 2 2 2 2 Phosphofructokinase TIR_2 PF13676.6 ORY42842.1 - 2.6e-09 37.7 0.6 1.6e-08 35.2 0.0 2.5 2 1 0 2 2 2 1 TIR domain DUF4349 PF14257.6 ORY42842.1 - 0.00012 21.6 0.7 0.00022 20.7 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) UTP15_C PF09384.10 ORY42842.1 - 0.0053 16.4 0.4 0.0092 15.7 0.4 1.4 1 0 0 1 1 1 1 UTP15 C terminal Cas9_b_hairpin PF17893.1 ORY42842.1 - 0.073 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain FAM76 PF16046.5 ORY42842.1 - 0.18 11.1 5.2 0.28 10.5 5.2 1.2 1 0 0 1 1 1 0 FAM76 protein IZUMO PF15005.6 ORY42842.1 - 0.6 10.6 3.2 1.3 9.6 3.2 1.5 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated BSD PF03909.17 ORY42843.1 - 1.4e-11 44.2 0.9 3.1e-11 43.1 0.2 1.9 2 0 0 2 2 2 1 BSD domain Syja_N PF02383.18 ORY42844.1 - 4.2e-71 239.9 0.0 5.7e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 ORY42844.1 - 2.1e-09 37.2 0.4 6.9e-08 32.3 0.1 2.3 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family COPIIcoated_ERV PF07970.12 ORY42845.1 - 2.3e-43 148.6 0.1 3.2e-43 148.1 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 ORY42845.1 - 4.5e-15 55.8 0.4 1.2e-14 54.4 0.2 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF4714 PF15833.5 ORY42845.1 - 0.11 12.4 0.2 0.2 11.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4714) Prenyltransf PF01255.19 ORY42846.1 - 1.3e-64 217.8 0.0 1.9e-64 217.3 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase DUF3858 PF12970.7 ORY42846.1 - 0.037 14.0 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3858) ATP-synt_E PF05680.12 ORY42847.1 - 3e-15 56.3 0.1 3.1e-15 56.3 0.1 1.0 1 0 0 1 1 1 1 ATP synthase E chain Nefa_Nip30_N PF10187.9 ORY42848.1 - 1.5e-18 67.1 1.9 1.5e-18 67.1 1.9 2.2 3 0 0 3 3 3 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.13 ORY42848.1 - 0.001 18.8 7.5 0.0013 18.5 7.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF1919 PF08942.10 ORY42851.1 - 0.0064 16.0 0.0 0.0097 15.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1919) FmdA_AmdA PF03069.15 ORY42851.1 - 0.082 11.8 0.1 0.084 11.7 0.1 1.1 1 0 0 1 1 1 0 Acetamidase/Formamidase family OrfB_Zn_ribbon PF07282.11 ORY42858.1 - 0.006 16.5 0.2 0.013 15.4 0.2 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Tropomyosin PF00261.20 ORY42858.1 - 0.045 13.1 22.5 0.42 9.9 22.5 2.1 1 1 0 1 1 1 0 Tropomyosin TMF_TATA_bd PF12325.8 ORY42858.1 - 1.9 8.8 19.6 0.079 13.2 6.2 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ATP-synt_DE PF00401.20 ORY42858.1 - 1.9 8.8 12.4 2 8.8 0.5 3.6 4 1 0 4 4 4 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DUF724 PF05266.14 ORY42858.1 - 7.7 6.3 16.1 1.7 8.5 11.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) BMFP PF04380.13 ORY42858.1 - 9.9 6.7 19.6 0.9 10.1 3.3 3.7 2 2 2 4 4 4 0 Membrane fusogenic activity DUF3818 PF12825.7 ORY42859.1 - 0.16 11.0 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) DUF745 PF05335.13 ORY42874.1 - 6.6e-07 29.2 34.6 0.00046 20.0 19.3 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF745) APG17 PF04108.12 ORY42874.1 - 1.1e-05 24.8 36.7 0.0016 17.6 21.0 2.4 1 1 1 2 2 2 2 Autophagy protein Apg17 MCPsignal PF00015.21 ORY42874.1 - 2.7e-05 24.1 6.3 0.029 14.2 1.8 2.4 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 ORY42874.1 - 0.00083 19.6 44.9 1.8e+04 -15.6 44.9 4.1 1 1 0 1 1 0 0 Bacterial protein of unknown function (DUF948) Glutaredoxin2_C PF04399.13 ORY42874.1 - 0.0013 18.6 33.1 1.4 8.8 2.3 4.9 2 1 3 5 5 5 1 Glutaredoxin 2, C terminal domain P4Ha_N PF08336.11 ORY42874.1 - 0.0033 17.4 32.9 5.7 7.0 10.1 4.0 1 1 1 2 2 1 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Syntaxin_2 PF14523.6 ORY42874.1 - 0.004 17.5 54.9 1.8e+04 -13.3 54.9 3.5 1 1 0 1 1 0 0 Syntaxin-like protein YkyA PF10368.9 ORY42874.1 - 0.0064 16.2 27.7 0.18 11.5 27.6 2.1 1 1 0 1 1 1 1 Putative cell-wall binding lipoprotein Laminin_I PF06008.14 ORY42874.1 - 0.019 14.7 51.5 0.051 13.3 51.5 1.8 1 1 0 1 1 1 0 Laminin Domain I RNase_E_G PF10150.9 ORY42874.1 - 0.024 14.0 15.4 0.027 13.9 8.2 2.0 1 1 1 2 2 2 0 Ribonuclease E/G family DUF883 PF05957.13 ORY42874.1 - 0.041 14.5 19.1 4.4 8.0 2.4 4.5 2 1 2 4 4 3 0 Bacterial protein of unknown function (DUF883) Sec34 PF04136.15 ORY42874.1 - 0.05 13.5 44.2 1.7 8.5 10.9 3.3 1 1 2 3 3 3 0 Sec34-like family FliT PF05400.13 ORY42874.1 - 0.34 11.7 25.8 1.8e+04 -9.9 25.8 4.2 1 1 0 1 1 0 0 Flagellar protein FliT CheZ PF04344.13 ORY42874.1 - 0.58 10.1 24.9 6.7 6.6 12.3 2.4 1 1 1 2 2 2 0 Chemotaxis phosphatase, CheZ Sec20 PF03908.13 ORY42874.1 - 1 9.3 37.3 6.2 6.8 11.6 3.4 1 1 3 4 4 4 0 Sec20 DUF4298 PF14131.6 ORY42874.1 - 1.3 9.0 41.8 4.8 7.2 5.9 4.6 2 1 3 6 6 5 0 Domain of unknown function (DUF4298) bVLRF1 PF18826.1 ORY42874.1 - 1.5 8.7 15.9 11 5.8 2.4 3.1 1 1 1 2 2 2 0 bacteroidetes VLRF1 release factor Mitovir_RNA_pol PF05919.11 ORY42874.1 - 1.7 7.7 25.2 2.1 7.4 25.2 1.1 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase ARGLU PF15346.6 ORY42874.1 - 2.1 8.2 19.8 4.1e+03 -2.5 19.8 2.7 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 GLTSCR1 PF15249.6 ORY42874.1 - 3.2 8.2 19.4 47 4.5 2.9 4.3 1 1 1 2 2 1 0 Conserved region of unknown function on GLTSCR protein Vezatin PF12632.7 ORY42874.1 - 3.6 6.9 52.2 4.2 6.7 8.5 4.1 1 1 2 3 3 2 0 Mysoin-binding motif of peroxisomes SKA2 PF16740.5 ORY42874.1 - 4.2 7.2 43.8 13 5.6 12.2 3.1 1 1 1 2 2 1 0 Spindle and kinetochore-associated protein 2 Perilipin PF03036.16 ORY42874.1 - 5 6.0 26.9 11 4.9 26.7 1.6 1 1 0 1 1 1 0 Perilipin family PAH PF02671.21 ORY42874.1 - 5.2 7.3 15.7 1.8e+04 -7.0 15.1 4.5 1 1 0 1 1 0 0 Paired amphipathic helix repeat BORCS7 PF16088.5 ORY42874.1 - 6.7 7.0 40.0 1.8e+04 -12.1 40.0 3.2 1 1 0 1 1 0 0 BLOC-1-related complex sub-unit 7 Exonuc_VII_L PF02601.15 ORY42874.1 - 8.4 5.9 40.9 1.3e+03 -1.3 40.9 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit OrfB_Zn_ribbon PF07282.11 ORY42878.1 - 0.006 16.5 0.2 0.013 15.4 0.2 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Tropomyosin PF00261.20 ORY42878.1 - 0.045 13.1 22.5 0.42 9.9 22.5 2.1 1 1 0 1 1 1 0 Tropomyosin TMF_TATA_bd PF12325.8 ORY42878.1 - 1.9 8.8 19.6 0.079 13.2 6.2 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ATP-synt_DE PF00401.20 ORY42878.1 - 1.9 8.8 12.4 2 8.8 0.5 3.6 4 1 0 4 4 4 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DUF724 PF05266.14 ORY42878.1 - 7.7 6.3 16.1 1.7 8.5 11.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) BMFP PF04380.13 ORY42878.1 - 9.9 6.7 19.6 0.9 10.1 3.3 3.7 2 2 2 4 4 4 0 Membrane fusogenic activity DUF3818 PF12825.7 ORY42879.1 - 0.16 11.0 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) CARD_2 PF16739.5 ORY42886.1 - 0.025 14.6 0.1 0.035 14.1 0.1 1.2 1 0 0 1 1 1 0 Caspase recruitment domain OrfB_Zn_ribbon PF07282.11 ORY42887.1 - 0.0088 16.0 0.2 0.02 14.8 0.2 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Tropomyosin PF00261.20 ORY42887.1 - 0.023 14.1 20.9 0.041 13.3 17.2 2.2 1 1 1 2 2 2 0 Tropomyosin Flexi_CP PF00286.20 ORY42887.1 - 0.48 10.3 4.8 0.18 11.7 0.6 2.0 2 0 0 2 2 2 0 Viral coat protein TMF_TATA_bd PF12325.8 ORY42887.1 - 3.7 7.8 19.4 0.13 12.5 5.9 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 ORY42887.1 - 9.1 5.1 17.6 3.1 6.6 0.3 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3818 PF12825.7 ORY42888.1 - 0.16 11.0 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) OrfB_Zn_ribbon PF07282.11 ORY42899.1 - 0.0062 16.4 0.2 0.013 15.4 0.2 1.6 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Tropomyosin PF00261.20 ORY42899.1 - 0.053 12.9 23.5 0.098 12.0 19.7 2.3 1 1 1 2 2 2 0 Tropomyosin TMF_TATA_bd PF12325.8 ORY42899.1 - 1.8 8.8 19.7 0.093 13.0 6.2 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ATP-synt_DE PF00401.20 ORY42899.1 - 1.9 8.8 12.4 2 8.8 0.5 3.7 4 1 0 4 4 4 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DUF724 PF05266.14 ORY42899.1 - 5.9 6.7 15.8 1.4 8.7 10.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Poty_PP PF08440.10 ORY42901.1 - 0.033 13.3 0.1 0.058 12.5 0.1 1.3 1 0 0 1 1 1 0 Potyviridae polyprotein DUF3818 PF12825.7 ORY42910.1 - 0.18 10.8 0.1 0.35 9.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) DUF1056 PF06341.11 ORY42911.1 - 0.0027 18.0 0.1 0.064 13.6 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF1056) FAM198 PF15051.6 ORY42912.1 - 0.16 10.8 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 FAM198 protein PPR_2 PF13041.6 ORY42915.1 - 1.3e-06 28.5 1.7 0.063 13.5 0.1 5.8 4 1 2 6 6 6 1 PPR repeat family PPR PF01535.20 ORY42915.1 - 5.3e-05 23.2 0.1 20 5.7 0.0 6.6 8 0 0 8 8 8 1 PPR repeat PPR_3 PF13812.6 ORY42915.1 - 0.011 15.7 0.1 0.25 11.5 0.1 2.9 3 0 0 3 3 3 0 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORY42915.1 - 0.032 13.9 0.5 0.63 9.8 0.1 2.9 3 0 0 3 3 3 0 PPR repeat PPR_long PF17177.4 ORY42915.1 - 0.049 13.0 0.1 0.38 10.1 0.0 2.5 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP T2SSF PF00482.23 ORY42915.1 - 0.057 13.4 0.0 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Herpes_TK_C PF08465.10 ORY42915.1 - 0.31 10.8 1.2 0.91 9.3 0.2 2.3 3 0 0 3 3 3 0 Thymidine kinase from Herpesvirus C-terminal DUF2660 PF10859.8 ORY42920.1 - 0.078 13.4 0.5 0.67 10.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2660) DUF1056 PF06341.11 ORY42921.1 - 0.29 11.5 2.7 5.1 7.5 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1056) OKR_DC_1_N PF03709.15 ORY42922.1 - 0.12 12.6 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain Hydin_ADK PF17213.3 ORY42927.1 - 7.8 6.7 11.1 0.57 10.4 4.5 2.0 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain Ank_2 PF12796.7 ORY42984.1 - 8.8e-15 55.1 0.0 3.4e-05 24.3 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY42984.1 - 2.4e-10 40.7 0.5 0.15 12.6 0.0 5.2 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY42984.1 - 1.5e-09 37.3 0.0 5.4 7.9 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 ORY42984.1 - 3.6e-06 27.2 0.1 6 7.3 0.0 5.1 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY42984.1 - 0.092 13.2 0.1 2.9e+02 2.2 0.0 4.8 5 1 0 5 5 5 0 Ankyrin repeat HATPase_c PF02518.26 ORY42987.1 - 2.6e-45 153.5 2.8 3.9e-23 82.1 0.2 3.0 3 0 0 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY42987.1 - 1.8e-42 144.0 0.9 5.8e-21 74.8 0.1 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 ORY42987.1 - 3.5e-23 81.4 0.3 6.5e-13 48.5 0.1 2.8 2 0 0 2 2 2 2 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 ORY42987.1 - 2.9e-07 30.7 0.1 6.2e-05 23.2 0.2 3.1 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 ORY42987.1 - 1.6e-05 24.9 0.1 0.00012 22.1 0.1 2.4 1 1 0 1 1 1 1 PAS fold PAS_4 PF08448.10 ORY42987.1 - 5.4e-05 23.4 0.0 0.057 13.7 0.0 2.7 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 ORY42987.1 - 0.0003 20.7 0.0 0.0013 18.7 0.0 2.2 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.12 ORY42987.1 - 0.0017 18.6 0.1 0.01 16.1 0.1 2.4 1 1 0 1 1 1 1 PAS fold HATPase_c_2 PF13581.6 ORY42987.1 - 0.029 14.3 0.0 3.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.6 ORY42987.1 - 0.049 13.5 0.0 0.4 10.5 0.0 2.4 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HTH_16 PF12645.7 ORY42987.1 - 0.11 12.5 0.0 0.35 10.9 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain ALMT PF11744.8 ORY42988.1 - 8.2e-07 28.2 0.4 1.6e-06 27.2 0.1 1.8 2 1 0 2 2 2 1 Aluminium activated malate transporter ArAE_2_N PF10337.9 ORY42988.1 - 0.00035 19.7 4.5 0.25 10.3 1.7 2.4 2 0 0 2 2 2 2 Putative ER transporter, 6TM, N-terminal BatD PF13584.6 ORY42989.1 - 0.021 13.6 0.2 0.028 13.3 0.2 1.0 1 0 0 1 1 1 0 Oxygen tolerance TAL_FSA PF00923.19 ORY42990.1 - 0.094 12.0 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Transaldolase/Fructose-6-phosphate aldolase Homeodomain PF00046.29 ORY42991.1 - 0.0017 18.1 0.0 0.0046 16.8 0.0 1.7 1 0 0 1 1 1 1 Homeodomain Ureide_permease PF07168.11 ORY42991.1 - 3.3 6.4 5.1 7.3 5.2 5.1 1.5 1 0 0 1 1 1 0 Ureide permease DUF4569 PF15133.6 ORY42991.1 - 3.9 7.1 7.8 23 4.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) E1-E2_ATPase PF00122.20 ORY42993.1 - 7e-47 159.3 2.9 2.8e-46 157.3 2.9 2.1 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 ORY42993.1 - 1.4e-18 68.0 0.1 3.1e-18 66.8 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY42993.1 - 4.1e-13 48.8 0.0 2.9e-12 46.1 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase_C PF00689.21 ORY42993.1 - 0.00013 21.8 8.9 0.00013 21.8 8.9 2.7 2 1 1 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORY42993.1 - 0.0055 16.8 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY42993.1 - 0.023 14.4 0.2 0.061 13.1 0.1 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TMEM171 PF15471.6 ORY42993.1 - 0.071 12.1 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Glyco_hydro_26 PF02156.15 ORY42994.1 - 0.0012 18.4 1.7 0.36 10.2 0.8 2.8 2 1 0 2 2 2 1 Glycosyl hydrolase family 26 EF-hand_5 PF13202.6 ORY42994.1 - 0.048 13.2 0.7 0.12 12.0 0.7 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 ORY42994.1 - 0.061 13.3 1.1 0.24 11.4 1.1 2.0 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 ORY42994.1 - 0.13 11.9 1.8 0.36 10.5 1.8 1.7 1 0 0 1 1 1 0 EF hand Thioredoxin PF00085.20 ORY42995.1 - 0.00013 21.9 0.0 0.0035 17.3 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Sec10 PF07393.11 ORY42996.1 - 0.11 10.8 1.2 0.16 10.3 1.2 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 EssA PF10661.9 ORY42997.1 - 0.22 11.3 0.2 0.46 10.3 0.0 1.5 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA DUF1356 PF07092.12 ORY42998.1 - 4.4e-05 22.9 0.1 6.2e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) LEA_2 PF03168.13 ORY42998.1 - 0.00024 21.6 0.1 0.00031 21.2 0.1 1.3 1 0 0 1 1 1 1 Late embryogenesis abundant protein Vac7 PF12751.7 ORY42998.1 - 0.0042 16.6 0.0 0.0056 16.2 0.0 1.1 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 NiFeSe_Hases PF00374.19 ORY43000.1 - 0.067 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Nickel-dependent hydrogenase RQC PF09382.10 ORY43000.1 - 0.099 12.4 0.0 12 5.7 0.0 2.5 2 0 0 2 2 2 0 RQC domain CsgE PF10627.9 ORY43001.1 - 0.12 12.7 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Curli assembly protein CsgE FMN_red PF03358.15 ORY43004.1 - 1.4e-24 86.6 0.0 1.8e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ORY43004.1 - 3.3e-05 23.7 0.0 4.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Ist1 PF03398.14 ORY43004.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Ank_2 PF12796.7 ORY43005.1 - 2.1e-09 37.9 0.0 6.5e-09 36.3 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY43005.1 - 1.3e-06 28.3 2.7 0.095 13.3 0.1 4.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 ORY43005.1 - 2.1e-06 28.2 1.8 0.11 13.0 0.0 3.0 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY43005.1 - 0.0023 18.2 3.3 1.1 9.6 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY43005.1 - 0.0085 16.5 4.5 0.39 11.2 0.4 3.6 3 1 1 4 4 4 1 Ankyrin repeat PDZ_5 PF17817.1 ORY43007.1 - 0.047 14.0 0.1 0.14 12.4 0.1 1.9 1 0 0 1 1 1 0 PDZ domain APC_N_CC PF16689.5 ORY43007.1 - 0.14 12.3 3.2 6.7 6.9 0.2 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain NBD94 PF16830.5 ORY43007.1 - 0.14 12.6 3.9 0.33 11.4 0.3 2.7 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH CENP-F_leu_zip PF10473.9 ORY43007.1 - 4.4 7.3 13.4 0.5 10.4 0.7 2.9 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADK PF00406.22 ORY43008.1 - 1.9e-45 154.6 0.0 2.3e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ORY43008.1 - 1.4e-35 122.6 0.0 2e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY43008.1 - 7.6e-09 36.2 0.0 1.2e-08 35.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 ORY43008.1 - 1.4e-05 24.8 0.2 0.031 13.9 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 ORY43008.1 - 0.00015 22.0 0.0 0.0011 19.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain RAG1 PF12940.7 ORY43009.1 - 0.0028 15.8 0.9 0.004 15.3 0.9 1.2 1 0 0 1 1 1 1 Recombination-activation protein 1 (RAG1), recombinase Filament PF00038.21 ORY43009.1 - 0.0045 16.6 12.2 0.043 13.4 4.3 2.2 1 1 1 2 2 2 2 Intermediate filament protein CtIP_N PF10482.9 ORY43009.1 - 0.041 13.9 9.1 0.72 9.9 6.7 3.0 2 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain IPPT PF01715.17 ORY43009.1 - 0.1 12.4 3.2 0.24 11.2 3.2 1.7 1 1 0 1 1 1 0 IPP transferase DUF4358 PF14270.6 ORY43009.1 - 0.33 11.3 4.9 0.15 12.4 0.9 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4358) ATG16 PF08614.11 ORY43009.1 - 0.37 11.0 14.5 0.17 12.1 3.6 2.7 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 ORY43009.1 - 0.62 10.1 5.7 2 8.5 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ZapB PF06005.12 ORY43009.1 - 1.6 9.2 10.5 2.9 8.4 3.1 3.0 1 1 1 2 2 2 0 Cell division protein ZapB Cep57_MT_bd PF06657.13 ORY43009.1 - 1.8 9.1 10.4 0.14 12.6 2.8 2.7 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Nup54 PF13874.6 ORY43009.1 - 2.1 8.4 8.4 6.5 6.9 8.4 1.9 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 FliD_N PF02465.18 ORY43009.1 - 3 8.6 8.0 10 6.9 5.4 2.8 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Lectin_N PF03954.14 ORY43009.1 - 3.1 7.5 6.4 0.85 9.4 0.8 2.2 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain V-SNARE PF05008.15 ORY43009.1 - 3.8 8.0 11.9 5.7 7.4 6.4 3.0 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DivIC PF04977.15 ORY43009.1 - 5.5 6.8 9.4 1.3 8.9 4.4 2.4 1 1 2 3 3 3 0 Septum formation initiator FapA PF03961.13 ORY43009.1 - 5.8 5.4 8.4 8.1 4.9 8.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF16 PF01519.16 ORY43009.1 - 8.8 6.9 9.7 3.7 8.1 1.7 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 Mei5 PF10376.9 ORY43010.1 - 0.1 12.4 20.4 0.26 11.1 20.2 1.8 1 1 1 2 2 2 0 Double-strand recombination repair protein TMPIT PF07851.13 ORY43010.1 - 0.14 11.3 9.6 0.19 10.9 9.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.6 ORY43010.1 - 0.24 10.7 12.0 0.33 10.2 12.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Consortin_C PF15281.6 ORY43010.1 - 0.49 10.4 0.0 0.49 10.4 0.0 2.3 1 1 2 3 3 3 0 Consortin C-terminus 7TMR-HDED PF07697.11 ORY43010.1 - 2.5 8.1 16.9 3.3 7.8 16.9 1.2 1 0 0 1 1 1 0 7TM-HD extracellular Neur_chan_memb PF02932.16 ORY43010.1 - 3.5 7.6 7.8 4.4 7.3 7.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Phage_GP20 PF06810.11 ORY43011.1 - 0.0034 17.2 13.3 0.0092 15.8 13.3 1.7 1 1 0 1 1 1 1 Phage minor structural protein GP20 ZapB PF06005.12 ORY43011.1 - 0.0045 17.4 4.4 0.0045 17.4 4.4 3.1 1 1 1 2 2 1 1 Cell division protein ZapB DivIC PF04977.15 ORY43011.1 - 0.0071 16.1 2.1 0.0071 16.1 2.1 3.6 1 1 3 4 4 4 1 Septum formation initiator TSC22 PF01166.18 ORY43011.1 - 0.033 14.5 0.6 0.033 14.5 0.6 2.9 2 1 0 2 2 2 0 TSC-22/dip/bun family Baculo_PEP_C PF04513.12 ORY43011.1 - 0.081 13.0 4.2 0.17 11.9 4.2 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2524 PF10732.9 ORY43011.1 - 0.26 11.6 17.4 0.16 12.3 11.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) MCC-bdg_PDZ PF10506.9 ORY43011.1 - 0.27 11.3 9.6 0.51 10.4 0.2 2.8 2 1 1 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome NPV_P10 PF05531.12 ORY43011.1 - 0.27 11.7 5.4 9.2 6.8 0.8 2.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Prominin PF05478.11 ORY43011.1 - 0.32 8.9 10.2 0.41 8.5 10.2 1.2 1 0 0 1 1 1 0 Prominin Exonuc_VII_L PF02601.15 ORY43011.1 - 0.47 10.0 15.6 0.61 9.6 15.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DDE_Tnp_IS66 PF03050.14 ORY43011.1 - 0.48 9.9 6.1 0.6 9.5 6.1 1.1 1 0 0 1 1 1 0 Transposase IS66 family DNA_pol3_a_NI PF14480.6 ORY43011.1 - 0.54 10.3 6.9 0.27 11.3 0.8 2.8 2 1 1 3 3 3 0 DNA polymerase III polC-type N-terminus I Herpes_UL6 PF01763.16 ORY43011.1 - 0.63 8.5 9.0 0.84 8.1 8.9 1.3 1 1 0 1 1 1 0 Herpesvirus UL6 like UPF0184 PF03670.13 ORY43011.1 - 0.7 10.3 4.5 0.3 11.5 0.7 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) YabA PF06156.13 ORY43011.1 - 0.74 10.5 15.1 1.1 9.9 1.9 2.5 1 1 1 2 2 2 0 Initiation control protein YabA DUF3584 PF12128.8 ORY43011.1 - 0.99 6.8 19.0 1.1 6.7 19.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HIP1_clath_bdg PF16515.5 ORY43011.1 - 1.2 9.8 21.7 0.93 10.1 14.6 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Fib_alpha PF08702.10 ORY43011.1 - 1.3 9.2 13.5 3.1 8.0 13.5 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.8 ORY43011.1 - 2 8.5 30.1 0.33 11.0 4.0 3.5 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Tup_N PF08581.10 ORY43011.1 - 2.3 8.6 20.0 5.3 7.4 13.4 2.6 1 1 1 2 2 2 0 Tup N-terminal PKcGMP_CC PF16808.5 ORY43011.1 - 3.3 7.6 14.8 1.1 9.2 1.2 3.3 3 1 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4407 PF14362.6 ORY43011.1 - 5.2 6.3 14.2 9.5 5.5 14.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_lysis PF03245.13 ORY43011.1 - 5.5 7.1 13.0 1.3e+03 -0.6 13.0 2.8 1 1 0 1 1 1 0 Bacteriophage Rz lysis protein FAM76 PF16046.5 ORY43011.1 - 6.5 6.0 17.3 5.5 6.3 5.5 2.0 1 1 1 2 2 2 0 FAM76 protein DUF3740 PF12548.8 ORY43011.1 - 9.4 6.7 11.3 0.87 10.0 1.4 2.3 1 1 1 2 2 2 0 Sulfatase protein ZZ PF00569.17 ORY43012.1 - 4.5e-13 48.8 7.0 7.6e-13 48.1 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.32 ORY43012.1 - 8.3e-12 43.8 8.8 4.6e-05 22.7 0.0 4.0 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 ORY43012.1 - 2.7e-11 43.7 1.4 0.00021 21.6 0.2 3.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 ORY43012.1 - 6.5e-10 38.1 4.7 9.8e-05 22.0 0.1 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 ORY43012.1 - 3.1e-08 33.3 2.5 0.0032 17.3 0.5 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 ORY43012.1 - 4e-07 29.2 8.9 0.00025 20.4 0.0 4.0 4 0 0 4 4 4 2 EF hand C1_2 PF03107.16 ORY43012.1 - 0.019 15.3 5.0 0.033 14.5 5.0 1.3 1 0 0 1 1 1 0 C1 domain SIR2 PF02146.17 ORY43013.1 - 1e-57 194.9 0.0 1.4e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Sir2 family HMG_box_5 PF14887.6 ORY43015.1 - 0.029 14.3 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box 5 NYN PF01936.18 ORY43018.1 - 0.016 15.7 0.0 1 9.9 0.0 2.2 2 0 0 2 2 2 0 NYN domain 2OG-FeII_Oxy_2 PF13532.6 ORY43020.1 - 5.7e-10 39.7 0.0 3.8e-09 37.0 0.0 1.8 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily Atrophin-1 PF03154.15 ORY43020.1 - 1.6 7.0 3.9 2.3 6.4 3.9 1.2 1 0 0 1 1 1 0 Atrophin-1 family MMR_HSR1_Xtn PF16897.5 ORY43021.1 - 1.2e-44 150.7 0.3 5.3e-44 148.6 0.2 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 ORY43021.1 - 1.3e-20 73.5 0.0 3.2e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 ORY43021.1 - 2.2e-18 66.1 0.1 4.7e-18 65.0 0.1 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 ORY43021.1 - 6.2e-12 45.3 0.1 3.6e-11 42.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 ORY43021.1 - 0.00037 19.6 0.6 0.011 14.8 0.3 2.5 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 ORY43021.1 - 0.0052 16.4 0.4 6.8 6.2 0.0 3.9 2 2 1 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 ORY43021.1 - 0.041 13.9 0.4 9.3 6.3 0.0 2.5 1 1 1 2 2 2 0 Dynamin family NB-ARC PF00931.22 ORY43021.1 - 0.049 12.8 0.1 0.089 12.0 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain G-gamma PF00631.22 ORY43022.1 - 6.2e-10 38.9 0.2 6.5e-10 38.9 0.2 1.0 1 0 0 1 1 1 1 GGL domain Alk_phosphatase PF00245.20 ORY43023.1 - 2e-53 181.9 0.0 3.8e-53 180.9 0.0 1.5 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 ORY43023.1 - 0.0058 16.0 0.0 0.015 14.6 0.0 1.6 2 0 0 2 2 2 1 Metalloenzyme superfamily Alk_phosphatase PF00245.20 ORY43024.1 - 1.2e-43 149.7 0.0 3.2e-43 148.3 0.0 1.7 1 1 0 1 1 1 1 Alkaline phosphatase TMEM108 PF15759.5 ORY43026.1 - 0.011 14.7 1.2 0.02 13.9 1.2 1.3 1 0 0 1 1 1 0 TMEM108 family DUF4604 PF15377.6 ORY43026.1 - 2.3 8.6 14.1 7.3 7.0 14.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF4407 PF14362.6 ORY43026.1 - 9.4 5.5 7.0 20 4.4 7.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) JHY PF15261.6 ORY43027.1 - 8.3e-05 23.3 2.0 8.3e-05 23.3 2.0 3.8 2 1 0 2 2 2 1 Jhy protein RNA_pol_3_Rpc31 PF11705.8 ORY43027.1 - 0.28 11.4 14.4 0.064 13.5 5.6 3.3 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 DUF5113 PF17140.4 ORY43027.1 - 0.64 9.8 1.5 1.4 8.8 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) Rep_4 PF05797.11 ORY43027.1 - 3 6.9 6.2 4.7 6.2 6.2 1.2 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) NOA36 PF06524.12 ORY43027.1 - 7.5 5.8 11.8 13 5.0 11.8 1.2 1 0 0 1 1 1 0 NOA36 protein Choline_transpo PF04515.12 ORY43028.1 - 4.2e-70 236.5 31.2 4.2e-70 236.5 31.2 2.4 3 0 0 3 3 3 1 Plasma-membrane choline transporter DUF1970 PF09301.10 ORY43028.1 - 1.3 9.3 3.7 3.5 7.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1970) GET2 PF08690.10 ORY43029.1 - 0.56 9.8 8.0 0.56 9.8 7.4 1.3 1 1 0 1 1 1 0 GET complex subunit GET2 UPF0370 PF13980.6 ORY43029.1 - 2.5 8.2 4.5 1.2 9.2 0.1 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0370) Aha1_N PF09229.11 ORY43030.1 - 4.5e-28 98.2 0.1 8.5e-28 97.3 0.1 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 ORY43030.1 - 2.4e-09 37.5 0.0 4.6e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DUF908 PF06012.12 ORY43030.1 - 0.023 14.2 0.4 0.03 13.8 0.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) zf-AN1 PF01428.16 ORY43031.1 - 5.2e-14 52.1 27.8 1.8e-07 31.2 4.3 3.1 2 1 1 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 ORY43031.1 - 0.00081 19.7 15.4 0.0059 16.9 1.7 2.3 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain ZZ PF00569.17 ORY43032.1 - 2.3e-07 30.5 7.7 4.2e-07 29.7 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type PB1 PF00564.24 ORY43032.1 - 2e-06 27.6 0.0 4.1e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 PB1 domain CUE PF02845.16 ORY43032.1 - 0.0048 16.6 0.1 0.01 15.5 0.1 1.5 1 0 0 1 1 1 1 CUE domain CH PF00307.31 ORY43033.1 - 1.2e-78 260.3 1.4 1.2e-20 73.7 0.0 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 ORY43033.1 - 4.7e-08 32.8 0.0 0.0064 16.3 0.0 3.3 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_7 PF13499.6 ORY43033.1 - 0.0057 17.1 0.0 0.017 15.5 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair DUF2666 PF10869.8 ORY43033.1 - 0.061 13.5 0.0 0.21 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) HTH_26 PF13443.6 ORY43033.1 - 0.19 12.2 0.2 0.69 10.4 0.1 2.0 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain TFIIA PF03153.13 ORY43033.1 - 8.7 6.2 9.3 13 5.6 9.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit cNMP_binding PF00027.29 ORY43034.1 - 1.2e-17 63.8 0.0 2.6e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF2671 PF10877.8 ORY43034.1 - 0.2 11.4 0.0 0.46 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2671) GLTP PF08718.11 ORY43035.1 - 1.2e-43 148.9 0.0 1.5e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) zf-C2H2 PF00096.26 ORY43036.1 - 3e-13 49.4 23.2 4.3e-06 26.9 3.8 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY43036.1 - 6.6e-10 39.0 20.7 0.00043 20.9 2.4 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY43036.1 - 7.2e-08 32.5 9.0 4.2e-05 23.8 1.3 3.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY43036.1 - 3.6e-06 26.8 14.7 0.063 13.3 0.3 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-LYAR PF08790.11 ORY43036.1 - 0.0012 18.6 11.7 0.034 14.1 1.1 3.3 3 0 0 3 3 3 2 LYAR-type C2HC zinc finger zf-C2H2_8 PF15909.5 ORY43036.1 - 0.0035 17.6 3.5 0.0035 17.6 3.5 1.9 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 ORY43036.1 - 0.013 15.8 14.4 0.022 15.0 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 ORY43036.1 - 0.021 14.5 6.5 0.45 10.2 0.2 2.5 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain C1_4 PF07975.12 ORY43036.1 - 0.03 14.5 3.1 0.03 14.5 3.1 2.0 1 1 1 2 2 2 0 TFIIH C1-like domain DUF1062 PF06353.12 ORY43036.1 - 0.058 14.2 1.0 0.089 13.6 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1062) HypA PF01155.19 ORY43036.1 - 0.071 13.1 3.3 0.15 12.1 3.3 1.5 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Actin_micro PF17003.5 ORY43036.1 - 0.091 11.9 2.0 0.097 11.8 2.0 1.2 1 0 0 1 1 1 0 Putative actin-like family zf-C2H2_2 PF12756.7 ORY43036.1 - 0.13 12.6 9.5 29 5.1 9.7 2.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_aberr PF17017.5 ORY43036.1 - 0.13 12.4 5.0 3.9 7.6 0.2 2.2 1 1 1 2 2 2 0 Aberrant zinc-finger FOXP-CC PF16159.5 ORY43036.1 - 0.16 12.6 6.8 2.2 9.0 1.0 2.3 1 1 1 2 2 2 0 FOXP coiled-coil domain DUF629 PF04780.12 ORY43036.1 - 0.36 9.3 6.0 1.8 7.0 6.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-met PF12874.7 ORY43036.1 - 0.4 11.1 0.2 0.4 11.1 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 ORY43036.1 - 0.6 10.3 8.5 1.3 9.2 5.1 2.6 2 1 1 3 3 3 0 Zinc ribbon domain zf-Di19 PF05605.12 ORY43036.1 - 0.62 10.4 9.7 0.45 10.9 4.9 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PHD PF00628.29 ORY43036.1 - 0.89 9.5 7.9 1.7 8.6 3.1 2.2 2 0 0 2 2 2 0 PHD-finger DHC_N1 PF08385.12 ORY43038.1 - 2.4e-163 544.8 14.8 2.4e-163 544.8 14.8 3.4 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 ORY43038.1 - 1.7e-158 526.8 0.0 2.6e-157 522.9 0.0 3.0 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 ORY43038.1 - 7.8e-130 433.6 8.1 7.8e-130 433.6 8.1 4.8 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 ORY43038.1 - 1.2e-98 329.6 0.0 3.3e-98 328.2 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 ORY43038.1 - 1e-84 283.1 0.7 2.7e-83 278.5 0.1 3.4 3 0 0 3 3 3 1 ATP-binding dynein motor region Dynein_C PF18199.1 ORY43038.1 - 7e-83 278.4 0.4 5.1e-82 275.5 0.0 2.7 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 ORY43038.1 - 1.5e-75 252.7 9.0 2.5e-72 242.2 0.0 4.5 5 0 0 5 5 4 2 P-loop containing dynein motor region MT PF12777.7 ORY43038.1 - 1.8e-57 195.0 13.4 5e-57 193.5 13.4 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 ORY43038.1 - 4.3e-52 176.2 0.1 1.2e-51 174.8 0.1 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 ORY43038.1 - 1.3e-44 151.1 0.0 3.1e-43 146.6 0.0 3.3 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_5 PF07728.14 ORY43038.1 - 3.9e-28 98.2 0.1 7e-08 32.6 0.0 5.6 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 ORY43038.1 - 3.4e-24 85.4 0.0 1.3e-23 83.5 0.0 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 ORY43038.1 - 6e-17 61.7 0.6 4.1e-16 59.0 0.1 2.7 2 0 0 2 2 2 1 AAA+ lid domain AAA PF00004.29 ORY43038.1 - 7.3e-09 36.1 0.1 0.68 10.4 0.0 6.1 6 0 0 6 6 5 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY43038.1 - 6.1e-08 33.0 0.7 0.11 12.8 0.0 5.3 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 ORY43038.1 - 5.3e-07 30.2 8.0 0.63 10.4 0.0 7.1 6 1 1 7 7 5 2 AAA ATPase domain AAA_18 PF13238.6 ORY43038.1 - 0.00024 21.7 0.3 3.5 8.2 0.0 4.8 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.6 ORY43038.1 - 0.0033 17.6 2.4 20 5.3 0.0 4.3 4 0 0 4 4 4 0 AAA domain Rsd_AlgQ PF04353.13 ORY43038.1 - 0.044 13.7 6.0 0.27 11.2 0.1 4.2 3 0 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ PhoH PF02562.16 ORY43038.1 - 0.091 12.2 1.0 1.3 8.4 0.0 3.3 3 0 0 3 3 2 0 PhoH-like protein TPR_20 PF14561.6 ORY43038.1 - 0.092 13.1 0.5 0.55 10.6 0.2 2.6 1 1 0 1 1 1 0 Tetratricopeptide repeat RsgA_GTPase PF03193.16 ORY43038.1 - 0.098 12.5 1.3 5.4 6.9 0.0 3.8 4 0 0 4 4 3 0 RsgA GTPase DUF2353 PF09789.9 ORY43038.1 - 0.12 11.8 19.5 1.4 8.2 2.6 4.1 3 0 0 3 3 3 0 Uncharacterized coiled-coil protein (DUF2353) Rad17 PF03215.15 ORY43038.1 - 0.13 12.2 3.3 23 4.8 0.1 3.9 4 0 0 4 4 3 0 Rad17 P-loop domain Mvb12 PF09452.10 ORY43038.1 - 0.14 12.6 2.3 7.8 7.0 0.0 4.2 4 0 0 4 4 3 0 ESCRT-I subunit Mvb12 AAA_30 PF13604.6 ORY43038.1 - 0.21 11.3 0.0 0.21 11.3 0.0 4.8 6 0 0 6 6 4 0 AAA domain AAA_25 PF13481.6 ORY43038.1 - 0.31 10.6 1.6 14 5.2 0.0 3.5 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.6 ORY43038.1 - 1.2 9.5 7.2 10 6.4 0.1 4.6 5 0 0 5 5 4 0 AAA domain BORCS7 PF16088.5 ORY43038.1 - 2.2 8.6 6.9 17 5.7 1.8 4.0 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 7 DUF4164 PF13747.6 ORY43038.1 - 3.3 8.1 14.7 0.47 10.8 5.2 3.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4164) BLUF PF04940.12 ORY43039.1 - 0.0018 18.4 0.0 0.0044 17.1 0.0 1.7 1 0 0 1 1 1 1 Sensors of blue-light using FAD DUF5067 PF16729.5 ORY43039.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5067) UQ_con PF00179.26 ORY43041.1 - 7e-39 132.7 0.1 8.5e-39 132.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY43041.1 - 0.14 12.5 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 RWD domain MutL_C PF08676.11 ORY43042.1 - 1.6e-24 86.4 0.0 1e-23 83.7 0.0 2.2 2 0 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 ORY43042.1 - 1.4e-23 82.9 0.5 3.8e-23 81.4 0.5 1.8 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 ORY43042.1 - 4.3e-09 36.3 2.8 4.9e-09 36.1 0.0 2.4 2 1 1 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ORY43042.1 - 9.7e-06 26.1 0.1 2.8e-05 24.6 0.1 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FAT PF02259.23 ORY43043.1 - 3.2e-97 325.9 2.9 3.2e-97 325.9 2.9 2.0 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 ORY43043.1 - 1.3e-74 251.2 1.0 3.4e-74 249.8 1.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 ORY43043.1 - 2.8e-44 150.8 9.7 2.8e-39 134.6 0.2 5.7 5 1 1 6 6 6 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 ORY43043.1 - 2.1e-39 133.9 0.2 2.1e-38 130.7 0.1 2.9 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 ORY43043.1 - 8.4e-17 61.3 9.2 8.4e-05 22.9 0.0 8.1 7 1 0 7 7 7 3 HEAT repeats FATC PF02260.20 ORY43043.1 - 4.7e-14 51.9 0.3 1.3e-13 50.5 0.3 1.9 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 ORY43043.1 - 1.4e-13 49.8 12.4 0.0064 16.7 0.0 10.1 10 0 0 10 10 8 3 HEAT repeat Vac14_Fab1_bd PF12755.7 ORY43043.1 - 4.4e-09 36.8 2.2 0.24 12.0 0.0 6.8 6 1 1 7 7 7 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 ORY43043.1 - 1.1e-07 32.2 11.8 0.29 11.7 0.0 8.0 9 0 0 9 9 8 2 HEAT-like repeat Cnd1 PF12717.7 ORY43043.1 - 3.1e-05 24.1 12.4 0.78 9.8 0.1 6.2 4 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 TPR_19 PF14559.6 ORY43043.1 - 0.029 14.9 0.3 8.4 7.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat IFRD PF05004.13 ORY43043.1 - 0.038 13.1 0.4 6.3 5.8 0.0 3.8 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) Imm58 PF15581.6 ORY43043.1 - 0.06 13.5 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Immunity protein 58 DUF3437 PF11919.8 ORY43043.1 - 0.21 11.6 1.1 18 5.4 0.1 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF3437) IFT20 PF14931.6 ORY43044.1 - 2e-36 124.7 11.4 2.3e-36 124.6 11.4 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 NPA PF16469.5 ORY43044.1 - 0.32 11.6 6.6 1.2 9.7 2.1 2.2 1 1 1 2 2 2 0 Nematode polyprotein allergen ABA-1 RSS_P20 PF11757.8 ORY43044.1 - 0.41 11.1 5.5 0.27 11.7 0.7 2.3 1 1 1 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain CH PF00307.31 ORY43045.1 - 1.7e-12 47.5 0.0 2.5e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain Rad21_Rec8_N PF04825.13 ORY43046.1 - 2.5e-18 66.2 0.0 6.4e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein UbiA PF01040.18 ORY43047.1 - 7.6e-58 195.8 26.8 9.7e-58 195.4 26.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family PTS_EIIB PF00367.20 ORY43047.1 - 0.44 10.1 1.2 0.85 9.2 1.2 1.5 1 0 0 1 1 1 0 phosphotransferase system, EIIB DUF1129 PF06570.11 ORY43047.1 - 4.4 6.7 6.2 0.38 10.2 0.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) RNA_pol_Rpb4 PF03874.16 ORY43048.1 - 5.4e-20 72.0 4.0 6.2e-20 71.8 4.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb4 HMGL-like PF00682.19 ORY43048.1 - 0.051 13.1 0.1 0.067 12.7 0.1 1.2 1 0 0 1 1 1 0 HMGL-like PAN_1 PF00024.26 ORY43049.1 - 0.0014 18.5 0.7 0.16 12.0 0.0 2.5 2 1 0 2 2 2 2 PAN domain PAN_4 PF14295.6 ORY43049.1 - 0.0069 16.3 1.9 0.016 15.1 1.9 1.6 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 ORY43049.1 - 0.0092 15.8 1.1 0.02 14.7 1.1 1.5 1 0 0 1 1 1 1 PAN-like domain DUF3144 PF11342.8 ORY43050.1 - 0.17 12.2 0.4 0.66 10.3 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3144) Ribosomal_L7Ae PF01248.26 ORY43052.1 - 1.5e-28 98.4 1.0 2.4e-28 97.7 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family OmpH PF03938.14 ORY43052.1 - 0.026 14.9 3.9 0.06 13.7 1.3 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CARD_2 PF16739.5 ORY43052.1 - 0.23 11.5 2.0 1.5 8.9 0.0 2.6 3 0 0 3 3 3 0 Caspase recruitment domain FAD_binding_7 PF03441.14 ORY43053.1 - 5.6e-79 264.3 0.0 8.6e-79 263.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 ORY43053.1 - 1.5e-44 151.9 0.5 2.5e-44 151.2 0.5 1.3 1 0 0 1 1 1 1 DNA photolyase Cytidylate_kin PF02224.18 ORY43054.1 - 0.017 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase HdeA PF06411.11 ORY43054.1 - 0.039 14.1 0.5 0.068 13.4 0.5 1.4 1 0 0 1 1 1 0 HdeA/HdeB family Polbeta PF18765.1 ORY43054.1 - 0.067 13.3 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Lipase_3 PF01764.25 ORY43055.1 - 1.1e-15 57.8 0.0 2.2e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 ORY43055.1 - 0.0046 16.3 0.0 0.015 14.6 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY43055.1 - 0.0093 16.6 0.1 0.0093 16.6 0.1 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Filament PF00038.21 ORY43056.1 - 0.00067 19.3 2.6 0.00067 19.3 2.6 2.0 2 0 0 2 2 2 1 Intermediate filament protein Tropomyosin_1 PF12718.7 ORY43056.1 - 0.014 15.5 6.0 0.014 15.5 6.0 2.7 2 1 1 3 3 2 0 Tropomyosin like TMF_TATA_bd PF12325.8 ORY43056.1 - 0.052 13.8 12.5 0.18 12.1 7.2 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding ATG16 PF08614.11 ORY43056.1 - 0.16 12.2 13.1 0.26 11.5 9.4 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 ORY43056.1 - 0.22 10.4 11.1 0.18 10.7 6.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein HalX PF08663.10 ORY43056.1 - 0.26 11.6 0.3 0.26 11.6 0.3 2.8 3 0 0 3 3 3 0 HalX domain Rx_N PF18052.1 ORY43056.1 - 0.77 10.1 4.8 0.78 10.1 0.2 2.5 2 1 0 2 2 2 0 Rx N-terminal domain CENP-F_leu_zip PF10473.9 ORY43056.1 - 0.83 9.7 11.7 1.2 9.1 7.5 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC85 PF10226.9 ORY43056.1 - 1.1 8.9 7.4 0.23 11.1 1.2 2.5 2 1 1 3 3 3 0 CCDC85 family ABC_tran_CTD PF16326.5 ORY43056.1 - 1.3 9.4 12.3 22 5.4 7.6 3.5 2 1 0 2 2 2 0 ABC transporter C-terminal domain NPV_P10 PF05531.12 ORY43056.1 - 2.3 8.7 7.3 14 6.2 0.2 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.13 ORY43056.1 - 3.5 8.4 6.2 23 5.8 3.5 2.9 2 1 0 2 2 2 0 Occludin homology domain YabA PF06156.13 ORY43056.1 - 4.6 7.9 7.7 6.1 7.5 0.9 3.0 2 2 1 3 3 3 0 Initiation control protein YabA Prefoldin_2 PF01920.20 ORY43056.1 - 5.4 7.0 13.4 20 5.2 7.5 3.4 2 1 0 2 2 2 0 Prefoldin subunit Fzo_mitofusin PF04799.13 ORY43056.1 - 6.2 6.4 7.1 2.5 7.6 1.4 2.5 2 1 1 3 3 3 0 fzo-like conserved region DUF1664 PF07889.12 ORY43056.1 - 8.6 6.4 7.0 17 5.5 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Rab5-bind PF09311.11 ORY43057.1 - 0.0081 15.6 3.7 0.0081 15.6 3.7 2.8 1 1 1 2 2 2 1 Rabaptin-like protein SecD-TM1 PF13721.6 ORY43057.1 - 0.077 13.5 10.9 0.073 13.5 2.2 2.5 1 1 1 2 2 2 0 SecD export protein N-terminal TM region Pox_A_type_inc PF04508.12 ORY43057.1 - 0.37 10.7 16.0 3.6 7.6 0.0 5.6 5 1 0 5 5 5 0 Viral A-type inclusion protein repeat Tropomyosin PF00261.20 ORY43057.1 - 1.6 8.1 49.9 0.56 9.5 8.1 3.1 1 1 2 3 3 3 0 Tropomyosin Gly_acyl_tr_N PF06021.11 ORY43057.1 - 3.7 7.6 8.0 1.8 8.6 4.9 1.9 1 1 1 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase Fez1 PF06818.15 ORY43057.1 - 9.4 6.6 37.0 1.6 9.1 8.4 3.2 1 1 2 3 3 3 0 Fez1 DSPc PF00782.20 ORY43058.1 - 5.8e-30 103.8 0.0 1.7e-29 102.3 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 ORY43058.1 - 1.2e-06 29.0 0.1 0.00013 22.4 0.0 2.8 3 0 0 3 3 3 1 Rhodanese-like domain Init_tRNA_PT PF04179.12 ORY43058.1 - 0.00057 20.2 0.1 0.0036 17.6 0.0 2.1 2 0 0 2 2 2 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 ORY43058.1 - 0.00079 19.1 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF240 PF03086.14 ORY43058.1 - 0.069 13.1 0.2 0.069 13.1 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF240) DSPn PF14671.6 ORY43058.1 - 0.15 12.5 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half Mif2_N PF15624.6 ORY43058.1 - 4.6 7.9 8.1 17 6.1 8.2 1.9 1 1 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal G-patch PF01585.23 ORY43059.1 - 1.3e-07 31.3 0.2 2.6e-07 30.4 0.2 1.5 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.8 ORY43059.1 - 8.3e-06 26.0 3.2 8.3e-06 26.0 3.2 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY43059.1 - 0.00021 21.6 0.9 0.00042 20.6 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type G-patch_2 PF12656.7 ORY43059.1 - 0.0046 17.0 0.1 0.014 15.5 0.1 1.9 1 0 0 1 1 1 1 G-patch domain Rrn6 PF10214.9 ORY43059.1 - 0.0092 14.5 1.0 0.01 14.4 1.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor zf-C2H2_2 PF12756.7 ORY43059.1 - 0.021 15.1 1.5 0.037 14.3 1.5 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 ORY43059.1 - 0.043 14.3 1.4 0.089 13.3 1.4 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-DBF PF07535.12 ORY43059.1 - 0.21 11.7 6.6 0.063 13.4 3.3 1.9 2 0 0 2 2 2 0 DBF zinc finger Tubulin PF00091.25 ORY43060.1 - 2.1e-70 237.0 0.0 3.9e-70 236.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORY43060.1 - 2.9e-47 160.0 0.6 4.7e-47 159.3 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 ORY43060.1 - 0.00019 21.7 0.0 0.0005 20.4 0.0 1.7 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 ORY43060.1 - 0.065 12.4 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Phosphodiest PF01663.22 ORY43061.1 - 6.5e-12 45.7 0.5 1.4e-11 44.6 0.1 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 ORY43061.1 - 0.0027 17.1 0.1 0.0044 16.4 0.1 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Arc_PepC_II PF06847.11 ORY43061.1 - 0.0071 16.8 0.1 0.019 15.4 0.1 1.7 1 0 0 1 1 1 1 Archaeal Peptidase A24 C-terminus Type II Sulfatase PF00884.23 ORY43061.1 - 0.15 11.4 0.1 0.46 9.8 0.0 1.8 2 0 0 2 2 2 0 Sulfatase Tubulin-binding PF00418.19 ORY43062.1 - 1.1e-41 140.5 7.5 5.7e-08 32.6 1.3 10.4 10 0 0 10 10 10 8 Tau and MAP protein, tubulin-binding repeat Tnp_22_dsRBD PF17490.2 ORY43062.1 - 0.00049 20.0 9.5 15 5.7 0.0 6.8 1 1 7 8 8 8 1 L1 transposable element dsRBD-like domain NPM1-C PF16276.5 ORY43062.1 - 0.0012 18.8 0.0 49 4.0 0.0 5.1 5 0 0 5 5 5 0 Nucleophosmin C-terminal domain DUF761 PF05553.11 ORY43062.1 - 0.0014 18.1 1.4 58 3.3 0.0 4.8 5 0 0 5 5 5 0 Cotton fibre expressed protein Coagulin PF02035.15 ORY43062.1 - 0.016 15.1 1.6 1.1 9.1 0.1 3.2 2 1 2 4 4 4 0 Coagulin Sa_NUDIX PF18167.1 ORY43062.1 - 0.44 10.3 8.2 6.3 6.6 0.1 4.3 2 2 1 5 5 5 0 SMODS-associated NUDIX domain Ribosomal_L36 PF00444.18 ORY43064.1 - 9.3e-15 54.6 2.0 1.3e-14 54.0 2.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 Cyt-b5 PF00173.28 ORY43065.1 - 7e-24 83.8 0.0 8.1e-24 83.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain LRR_6 PF13516.6 ORY43066.1 - 5.7e-15 54.0 17.3 8.4e-06 25.4 0.1 10.1 10 0 0 10 10 10 3 Leucine Rich repeat LRR_4 PF12799.7 ORY43066.1 - 4.2e-09 36.5 17.4 0.011 16.2 0.1 6.7 5 1 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY43066.1 - 5.4e-05 22.9 22.7 0.0035 17.1 0.9 6.1 5 2 2 7 7 7 3 Leucine rich repeat zf-ribbon_3 PF13248.6 ORY43066.1 - 0.13 11.7 0.4 0.3 10.6 0.4 1.6 1 0 0 1 1 1 0 zinc-ribbon domain LRR_1 PF00560.33 ORY43066.1 - 0.3 11.8 18.1 35 5.5 0.0 8.3 8 2 1 9 9 9 0 Leucine Rich Repeat GHMP_kinases_N PF00288.26 ORY43067.1 - 1e-10 41.7 0.3 2.1e-10 40.7 0.3 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ORY43067.1 - 0.0057 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Gar1 PF04410.14 ORY43068.1 - 1.1e-38 132.4 0.0 1.3e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region LMWPc PF01451.21 ORY43069.1 - 7.3e-44 149.6 0.0 8.2e-44 149.4 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DUF1682 PF07946.14 ORY43070.1 - 1.3e-63 215.2 0.1 1.7e-63 214.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Peptidase_M20 PF01546.28 ORY43071.1 - 4.2e-30 105.0 0.0 7.3e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY43071.1 - 1.9e-10 40.6 0.0 3.5e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ORY43071.1 - 0.0014 18.3 0.0 0.062 13.0 0.0 2.4 2 0 0 2 2 2 1 Peptidase family M28 DUF3357 PF11837.8 ORY43071.1 - 0.16 12.4 0.1 0.27 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) MTP18 PF10558.9 ORY43072.1 - 1.3e-52 178.3 1.6 6.4e-26 91.3 0.1 2.1 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) DUF4606 PF15379.6 ORY43074.1 - 0.00049 20.3 0.7 0.0012 19.1 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4606) TadE PF07811.12 ORY43075.1 - 0.17 12.2 1.8 1.6 9.1 0.0 2.7 2 0 0 2 2 2 0 TadE-like protein DAD PF02109.16 ORY43076.1 - 8.9e-38 129.0 2.4 9.8e-38 128.8 2.4 1.0 1 0 0 1 1 1 1 DAD family MNHE PF01899.16 ORY43076.1 - 0.13 12.0 1.0 0.15 11.8 0.6 1.4 1 1 0 1 1 1 0 Na+/H+ ion antiporter subunit Macoilin PF09726.9 ORY43077.1 - 0.04 12.5 5.1 0.049 12.2 5.1 1.1 1 0 0 1 1 1 0 Macoilin family V_ATPase_I PF01496.19 ORY43077.1 - 2.5 5.9 4.1 3.1 5.6 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SH3_9 PF14604.6 ORY43078.1 - 5.5e-07 29.3 0.0 1.2e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY43078.1 - 1.1e-06 28.1 0.0 2.1e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY43078.1 - 0.0035 17.0 0.0 0.0096 15.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SKG6 PF08693.10 ORY43078.1 - 0.041 13.3 0.4 0.12 11.9 0.4 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PI3_PI4_kinase PF00454.27 ORY43079.1 - 1.7e-35 123.0 0.0 1.3e-34 120.1 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 ORY43079.1 - 0.00018 21.0 0.2 0.00036 20.0 0.2 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 ORY43079.1 - 0.011 15.0 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Cyt-b5 PF00173.28 ORY43080.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain TPH PF13868.6 ORY43081.1 - 5.7e-07 28.4 59.8 5.7e-07 28.4 59.8 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Arf PF00025.21 ORY43082.1 - 2e-78 261.8 0.1 2.3e-78 261.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORY43082.1 - 4.4e-14 52.7 0.0 6e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 ORY43082.1 - 1.2e-12 47.7 0.0 1.5e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 ORY43082.1 - 1.9e-12 47.0 1.3 1.5e-08 34.2 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 ORY43082.1 - 2e-12 47.0 0.0 2.3e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 ORY43082.1 - 2.9e-10 39.9 0.0 3.6e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY43082.1 - 9.1e-06 25.7 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 ORY43082.1 - 0.0076 15.6 0.2 0.028 13.7 0.1 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase WD40 PF00400.32 ORY43083.1 - 3.8e-18 65.5 8.3 9.8e-07 29.4 0.6 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY43083.1 - 1.2e-06 28.7 0.1 2.7 8.4 0.0 4.7 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 ORY43083.1 - 0.0063 14.9 0.0 0.2 9.9 0.0 2.5 3 0 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_2 PF13360.6 ORY43083.1 - 0.02 14.5 0.5 0.075 12.6 0.5 1.8 1 1 0 1 1 1 0 PQQ-like domain SWIRM PF04433.17 ORY43084.1 - 0.00024 21.4 0.0 0.00056 20.2 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain SDA1 PF05285.12 ORY43084.1 - 0.0023 17.4 3.4 0.0023 17.4 3.4 1.6 2 0 0 2 2 2 1 SDA1 Nop14 PF04147.12 ORY43084.1 - 0.015 13.5 11.3 0.026 12.7 11.3 1.3 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 ORY43084.1 - 0.11 11.8 10.7 0.009 15.4 5.6 1.7 2 0 0 2 2 2 0 BUD22 Fungus-induced PF10917.8 ORY43084.1 - 0.33 11.3 4.0 1.6 9.1 4.0 2.2 1 0 0 1 1 1 0 Fungus-induced protein Sigma70_ner PF04546.13 ORY43084.1 - 0.38 10.6 7.3 0.98 9.3 7.3 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 ORY43084.1 - 0.81 7.9 12.2 0.015 13.6 5.6 1.4 2 0 0 2 2 2 0 CDC45-like protein TRAP_alpha PF03896.16 ORY43084.1 - 0.86 8.8 5.3 1.9 7.6 5.3 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF719 PF05334.13 ORY43084.1 - 1.1 9.4 7.8 1.4 9.1 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Polyketide_cyc PF03364.20 ORY43085.1 - 4.2e-15 56.1 0.0 3.3e-14 53.2 0.0 2.0 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport TRADD_N PF09034.10 ORY43086.1 - 0.019 15.0 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 TRADD, N-terminal domain ABC_tran PF00005.27 ORY43087.1 - 3e-31 108.8 0.0 7.2e-31 107.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ORY43087.1 - 3.2e-29 102.4 2.6 4.6e-29 101.9 2.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ORY43087.1 - 6.6e-09 35.5 0.5 2.3e-07 30.5 0.0 2.1 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 ORY43087.1 - 0.00027 19.9 0.0 0.00055 18.9 0.0 1.4 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 ORY43087.1 - 0.00051 20.3 0.7 0.0085 16.4 0.7 2.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ORY43087.1 - 0.0023 17.2 0.1 0.015 14.6 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.6 ORY43087.1 - 0.0032 18.0 0.0 0.0092 16.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 ORY43087.1 - 0.0078 16.0 0.1 0.11 12.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase PRK PF00485.18 ORY43087.1 - 0.0085 15.8 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 ORY43087.1 - 0.014 14.9 0.0 0.21 11.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 ORY43087.1 - 0.02 14.8 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_21 PF13304.6 ORY43087.1 - 0.031 14.1 0.1 0.2 11.5 0.0 2.1 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY43087.1 - 0.041 13.6 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 ORY43087.1 - 0.11 12.6 0.2 0.36 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 ORY43087.1 - 0.2 11.9 0.6 2.9 8.2 0.6 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.6 ORY43087.1 - 0.26 10.9 0.0 0.41 10.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain OrfB_Zn_ribbon PF07282.11 ORY43089.1 - 0.00037 20.4 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Aminotran_4 PF01063.19 ORY43090.1 - 4.2e-28 98.7 0.0 1.1e-27 97.4 0.0 1.6 2 0 0 2 2 2 1 Amino-transferase class IV DUF1279 PF06916.13 ORY43091.1 - 3.7e-09 37.0 0.1 6e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) RabGAP-TBC PF00566.18 ORY43092.1 - 2.6e-22 79.6 2.1 3.9e-12 46.3 0.3 3.8 2 1 0 2 2 2 2 Rab-GTPase-TBC domain Spore_YtfJ PF09579.10 ORY43092.1 - 8.3 6.7 7.2 11 6.3 0.2 2.5 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) TIP41 PF04176.13 ORY43093.1 - 8.2e-61 204.4 0.1 1.1e-60 204.1 0.1 1.1 1 0 0 1 1 1 1 TIP41-like family Rpr2 PF04032.16 ORY43094.1 - 7.6e-10 38.9 0.0 2.2e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain FYVE PF01363.21 ORY43094.1 - 0.044 13.9 0.7 0.29 11.3 1.2 2.0 1 1 1 2 2 2 0 FYVE zinc finger DUF4813 PF16072.5 ORY43094.1 - 0.056 13.1 10.1 0.022 14.5 7.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) GHMP_kinases_C PF08544.13 ORY43094.1 - 0.15 12.4 1.7 1.2 9.6 0.0 2.3 2 0 0 2 2 2 0 GHMP kinases C terminal zf-C2H2_6 PF13912.6 ORY43094.1 - 1.1 9.4 6.1 5.5 7.1 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2981 PF11200.8 ORY43094.1 - 8.8 6.0 7.6 13 5.4 7.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) CbtA PF09490.10 ORY43095.1 - 0.0066 16.2 4.6 0.076 12.8 0.7 2.4 2 1 0 2 2 2 2 Probable cobalt transporter subunit (CbtA) COX7a PF02238.15 ORY43095.1 - 0.085 13.3 0.5 0.085 13.3 0.5 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VII DUF2456 PF10445.9 ORY43095.1 - 2.3 8.4 8.9 0.2 11.7 1.3 2.9 2 2 1 3 3 3 0 Protein of unknown function (DUF2456) GNAT_acetyltr_2 PF13718.6 ORY43096.1 - 7.4e-89 297.0 0.0 2.4e-88 295.4 0.0 1.8 2 0 0 2 2 2 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 ORY43096.1 - 1.4e-64 218.0 6.3 1.9e-63 214.4 6.3 2.2 1 1 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 ORY43096.1 - 1.1e-61 207.7 0.0 4.2e-61 205.9 0.0 2.0 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 ORY43096.1 - 3.1e-32 110.4 0.3 8.7e-32 108.9 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) Acetyltransf_1 PF00583.25 ORY43096.1 - 0.0084 16.3 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Sigma70_r4_2 PF08281.12 ORY43096.1 - 0.043 13.5 1.4 0.37 10.5 0.0 3.1 3 0 0 3 3 3 0 Sigma-70, region 4 DEAD PF00270.29 ORY43096.1 - 0.092 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase MOR2-PAG1_N PF14222.6 ORY43097.1 - 1.6e-17 63.7 6.7 1.1e-16 61.0 6.7 2.3 1 1 0 1 1 1 1 Cell morphogenesis N-terminal Adaptin_N PF01602.20 ORY43097.1 - 0.011 14.4 3.1 0.2 10.2 0.0 3.3 3 0 0 3 3 3 0 Adaptin N terminal region HEAT PF02985.22 ORY43097.1 - 0.015 15.5 0.1 12 6.5 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat Ribosomal_L5_C PF00673.21 ORY43098.1 - 2.3e-22 79.0 0.0 3.4e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 ORY43098.1 - 7.9e-19 67.7 0.0 5.7e-18 65.0 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L5 GDP_Man_Dehyd PF16363.5 ORY43099.1 - 5e-163 542.2 0.0 5.9e-163 542.0 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY43099.1 - 3e-75 252.8 0.1 3.8e-75 252.5 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORY43099.1 - 1.7e-05 24.1 0.0 2.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ORY43099.1 - 0.0012 18.0 0.0 0.0023 17.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ORY43099.1 - 0.0031 17.1 0.0 0.0055 16.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family WG_beta_rep PF14903.6 ORY43102.1 - 0.1 12.9 0.1 0.34 11.3 0.1 1.9 1 0 0 1 1 1 0 WG containing repeat SYCP2_SLD PF18584.1 ORY43102.1 - 0.11 12.8 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Synaptonemal complex 2 Spt16M-like domain Nse4_C PF08743.10 ORY43103.1 - 1.5e-30 105.3 0.3 1.4e-29 102.2 0.0 2.7 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 ORY43103.1 - 6.1e-08 32.7 0.7 6.1e-08 32.7 0.7 3.9 3 1 0 3 3 3 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF4411 PF14367.6 ORY43103.1 - 0.01 15.8 0.5 0.039 13.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4411) CENP-B_dimeris PF09026.10 ORY43103.1 - 0.16 12.3 30.7 0.33 11.4 20.9 2.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain SART-1 PF03343.13 ORY43103.1 - 2.7 6.5 37.4 9.4 4.7 37.6 1.6 1 1 0 1 1 1 0 SART-1 family YL1 PF05764.13 ORY43103.1 - 3.4 7.7 40.6 0.6 10.2 21.6 2.4 1 1 1 2 2 2 0 YL1 nuclear protein Ferric_reduct PF01794.19 ORY43104.1 - 1.2e-20 73.8 10.0 1.2e-20 73.8 10.0 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 ORY43104.1 - 6.7e-09 36.0 0.0 1.2e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 ORY43104.1 - 1.5e-06 28.2 0.1 4.1e-05 23.6 0.1 2.3 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 ORY43104.1 - 0.12 13.0 0.0 1.1 9.9 0.0 2.4 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain Syntaxin-18_N PF10496.9 ORY43106.1 - 0.0019 18.4 0.2 0.012 15.9 0.0 2.5 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus Ntox10 PF15520.6 ORY43106.1 - 0.18 11.6 0.7 5.6 6.8 0.0 2.7 2 1 1 3 3 3 0 Novel toxin 10 Glyco_transf_34 PF05637.12 ORY43107.1 - 2.2e-17 63.6 0.1 7.7e-09 35.6 0.0 2.6 2 0 0 2 2 2 2 galactosyl transferase GMA12/MNN10 family Glyco_transf_8 PF01501.20 ORY43107.1 - 1.3e-05 24.9 0.1 3e-05 23.7 0.1 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 ORY43107.1 - 0.0033 17.4 0.4 0.1 12.6 0.0 2.3 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase Zip PF02535.22 ORY43108.1 - 1.2e-36 126.7 20.7 1.2e-28 100.3 12.0 2.9 2 1 1 3 3 3 3 ZIP Zinc transporter Neuromodulin_N PF10580.9 ORY43108.1 - 0.5 10.2 1.6 0.67 9.8 0.2 1.9 2 0 0 2 2 2 0 Gap junction protein N-terminal region PGAP1 PF07819.13 ORY43109.1 - 5.4e-41 140.8 2.9 8.8e-41 140.1 2.9 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.11 ORY43109.1 - 1e-07 31.6 0.2 0.00037 19.9 0.1 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.14 ORY43109.1 - 3.8e-06 26.6 0.2 7.1e-06 25.7 0.2 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_2 PF01674.18 ORY43109.1 - 3.3e-05 23.5 0.0 5.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) Palm_thioest PF02089.15 ORY43109.1 - 0.00067 19.6 0.1 0.00099 19.0 0.1 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Hydrolase_4 PF12146.8 ORY43109.1 - 0.0028 17.0 0.1 0.024 13.9 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY43109.1 - 0.0029 17.3 0.1 0.0057 16.3 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 ORY43109.1 - 0.0067 16.0 0.7 0.014 14.9 0.7 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.15 ORY43109.1 - 0.033 13.4 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 ORY43109.1 - 0.061 13.9 0.1 0.11 13.1 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 ORY43109.1 - 0.068 12.9 0.0 0.17 11.6 0.0 1.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family bPH_4 PF06713.11 ORY43109.1 - 0.086 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial PH domain Ribosomal_S15 PF00312.22 ORY43110.1 - 2.1e-24 85.5 0.3 3.9e-24 84.7 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 UL42 PF17638.2 ORY43111.1 - 0.18 11.8 0.2 0.18 11.8 0.2 1.7 2 0 0 2 2 2 0 HCMV UL42 Ank_2 PF12796.7 ORY43112.1 - 5.5e-30 103.8 3.9 6.3e-10 39.5 0.1 2.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY43112.1 - 4.3e-18 65.4 0.9 1.8e-05 25.2 0.0 3.9 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY43112.1 - 8.2e-17 61.1 0.1 3.9e-08 33.4 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY43112.1 - 5.8e-13 47.8 0.1 0.0071 16.8 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 ORY43112.1 - 6.1e-09 35.9 0.0 0.011 16.1 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat NIF PF03031.18 ORY43113.1 - 9.9e-13 48.1 0.0 5.8e-11 42.4 0.0 2.3 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Pkinase_Tyr PF07714.17 ORY43114.1 - 1.2e-42 146.0 0.0 3.9e-28 98.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 ORY43114.1 - 4.7e-38 131.1 0.0 1.6e-37 129.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain SHD1 PF03983.12 ORY43114.1 - 2e-13 49.9 0.0 6.1e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 ENTH PF01417.20 ORY43114.1 - 3.3e-12 46.5 0.0 7.3e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 ENTH domain SAM_2 PF07647.17 ORY43114.1 - 6.3e-06 26.2 0.0 1.9e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 ORY43114.1 - 0.012 15.5 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain SAM_1 PF00536.30 ORY43114.1 - 0.21 12.0 0.8 0.58 10.6 0.1 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Atg14 PF10186.9 ORY43115.1 - 1.1 8.3 14.0 0.54 9.3 4.4 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5595 PF18077.1 ORY43115.1 - 2.7 8.1 6.5 6.9 6.8 0.5 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) SAPS PF04499.15 ORY43116.1 - 5.6e-95 319.0 1.0 5e-57 193.8 1.2 2.9 3 0 0 3 3 3 2 SIT4 phosphatase-associated protein YqzH PF14164.6 ORY43116.1 - 0.0095 16.0 0.0 0.78 9.8 0.0 2.8 2 0 0 2 2 2 1 YqzH-like protein Cellulase PF00150.18 ORY43117.1 - 7.8e-29 101.0 0.0 2e-28 99.6 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 ORY43117.1 - 9.4e-07 29.3 0.0 1.9e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_42 PF02449.15 ORY43117.1 - 0.0003 20.2 0.0 0.00045 19.7 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 ORY43117.1 - 0.00048 19.9 0.0 0.0008 19.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_53 PF07745.13 ORY43117.1 - 0.18 10.8 0.0 0.46 9.4 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 53 Cellulase PF00150.18 ORY43118.1 - 1.4e-26 93.6 0.0 3.3e-26 92.4 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 ORY43118.1 - 4.5e-09 36.7 0.0 8.2e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_35 PF01301.19 ORY43118.1 - 0.00065 19.4 0.1 0.0017 18.1 0.0 1.7 1 1 0 2 2 2 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 ORY43118.1 - 0.001 18.5 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_1 PF00232.18 ORY43118.1 - 0.052 12.0 0.0 0.17 10.2 0.0 1.8 1 1 1 2 2 2 0 Glycosyl hydrolase family 1 DUF4951 PF16309.5 ORY43118.1 - 0.13 12.4 0.1 1.9 8.6 0.0 2.6 3 0 0 3 3 3 0 Domian of unknown function (DUF4951) Cellulase PF00150.18 ORY43119.1 - 3.7e-26 92.2 0.0 1.1e-25 90.6 0.0 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 ORY43119.1 - 9.8e-07 29.2 0.0 1.9e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_35 PF01301.19 ORY43119.1 - 0.00034 20.4 0.0 0.00054 19.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 ORY43119.1 - 0.00076 18.9 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_53 PF07745.13 ORY43119.1 - 0.062 12.3 0.0 0.15 11.0 0.0 1.5 2 0 0 2 2 2 0 Glycosyl hydrolase family 53 Myb_DNA-bind_2 PF08914.11 ORY43120.1 - 3.4e-13 49.6 0.0 6.3e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.10 ORY43120.1 - 0.0056 17.3 0.0 0.013 16.1 0.0 1.6 1 0 0 1 1 1 1 Rap1, DNA-binding RsdA_SigD_bd PF16751.5 ORY43120.1 - 0.018 15.3 0.4 23 5.3 0.1 3.5 3 0 0 3 3 3 0 Anti-sigma-D factor RsdA to sigma factor binding region MIT PF04212.18 ORY43121.1 - 1.6e-06 28.1 0.3 4.6e-06 26.6 0.3 1.9 1 1 0 1 1 1 1 MIT (microtubule interacting and transport) domain ABC_tran PF00005.27 ORY43122.1 - 2.1e-23 83.4 0.0 4.2e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ORY43122.1 - 2.3e-10 40.6 0.0 3.1e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ORY43122.1 - 0.00019 20.9 0.4 0.0017 17.8 0.4 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORY43122.1 - 0.0073 16.6 0.0 0.018 15.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 ORY43122.1 - 0.027 14.3 0.2 5.4 6.7 0.0 2.4 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 ORY43122.1 - 0.036 14.3 0.1 0.089 13.0 0.1 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 ORY43122.1 - 0.047 13.4 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 ORY43122.1 - 0.048 13.8 0.3 0.12 12.5 0.3 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 ORY43122.1 - 0.13 12.3 0.1 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DEAD PF00270.29 ORY43122.1 - 0.2 11.4 0.7 2.5 7.9 0.7 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase Gly-rich_Ago1 PF12764.7 ORY43123.1 - 2.2 9.1 5.9 3.1 8.6 5.9 1.2 1 0 0 1 1 1 0 Glycine-rich region of argonaut ABC_membrane PF00664.23 ORY43124.1 - 1.5e-18 67.4 2.9 7.9e-18 65.1 2.9 2.1 1 1 0 1 1 1 1 ABC transporter transmembrane region CENP-B_dimeris PF09026.10 ORY43124.1 - 0.24 11.8 2.3 0.51 10.8 2.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Peptidase_M17 PF00883.21 ORY43125.1 - 3.4e-86 289.3 0.2 5.8e-86 288.6 0.2 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 ORY43125.1 - 2.8e-10 40.5 0.1 2.8e-10 40.5 0.1 2.7 3 1 0 3 3 3 1 M17 aminopeptidase N-terminal domain 2 DUF2258 PF10015.9 ORY43125.1 - 0.074 13.2 0.0 0.36 11.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) Peptidase_M17 PF00883.21 ORY43127.1 - 9.9e-88 294.4 2.1 1.9e-87 293.5 2.1 1.4 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 ORY43127.1 - 1.1e-10 41.9 2.5 1.2e-10 41.7 0.7 2.0 2 0 0 2 2 2 1 M17 aminopeptidase N-terminal domain 2 YscJ_FliF_C PF08345.11 ORY43127.1 - 0.96 9.8 3.3 1.5 9.2 0.2 2.5 3 0 0 3 3 3 0 Flagellar M-ring protein C-terminal Pescadillo_N PF06732.11 ORY43128.1 - 2e-115 385.0 0.2 2e-115 385.0 0.2 2.0 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 ORY43128.1 - 2e-11 44.1 0.0 5.2e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 ORY43128.1 - 7.7e-06 26.2 0.0 3.6e-05 24.1 0.0 2.1 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Speriolin_C PF15059.6 ORY43128.1 - 0.14 12.3 0.0 0.44 10.7 0.0 1.9 1 0 0 1 1 1 0 Speriolin C-terminus DUF3246 PF11596.8 ORY43128.1 - 0.26 10.7 7.9 1.9 7.9 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) DUF4758 PF15950.5 ORY43128.1 - 0.28 11.5 1.1 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 Putative sperm flagellar membrane protein Tub PF01167.18 ORY43129.1 - 2.4e-65 220.7 1.2 1.8e-32 113.0 0.0 2.0 2 0 0 2 2 2 2 Tub family Cofilin_ADF PF00241.20 ORY43130.1 - 4.5e-23 81.4 0.0 5.3e-23 81.1 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Molybdopterin PF00384.22 ORY43131.1 - 1.2e-71 242.0 0.0 3.5e-70 237.2 0.0 2.2 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 ORY43131.1 - 1.3e-19 70.0 0.0 3.2e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 ORY43131.1 - 1.7e-16 59.5 0.1 1.7e-16 59.5 0.1 2.0 3 0 0 3 3 3 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 ORY43131.1 - 1.2e-13 51.5 0.4 3.3e-13 50.1 0.4 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 ORY43131.1 - 1.1e-09 38.1 1.8 2.7e-09 36.8 0.2 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 ORY43131.1 - 0.0029 17.3 0.4 0.26 11.0 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF4452 PF14618.6 ORY43132.1 - 0.0038 17.1 0.5 0.011 15.6 0.4 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4452) TMF_TATA_bd PF12325.8 ORY43132.1 - 3.6 7.8 40.8 0.22 11.7 7.7 3.7 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF563 PF04577.14 ORY43134.1 - 1.8e-22 80.5 0.0 8.2e-22 78.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF563) O-FucT PF10250.9 ORY43134.1 - 7.2e-18 65.4 0.0 1.6e-17 64.2 0.0 1.6 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.16 ORY43134.1 - 0.035 13.3 0.1 0.091 12.0 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 11 Antimicrobial12 PF08107.11 ORY43134.1 - 0.038 13.8 1.4 0.094 12.5 1.4 1.7 1 0 0 1 1 1 0 Pleurocidin family RNA_pol_Rpb1_5 PF04998.17 ORY43135.1 - 5.6e-85 285.0 2.1 8.9e-85 284.3 2.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 ORY43135.1 - 2.2e-80 270.3 0.0 3.7e-80 269.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 ORY43135.1 - 1e-73 247.1 0.0 1.8e-73 246.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 ORY43135.1 - 2.4e-34 118.5 0.0 5.6e-34 117.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 ORY43135.1 - 1.6e-28 98.8 0.0 4.3e-28 97.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RecR PF02132.15 ORY43135.1 - 0.2 11.3 2.3 2.3 7.8 0.4 2.9 2 0 0 2 2 2 0 RecR protein PPR_2 PF13041.6 ORY43136.1 - 6.7e-35 119.1 4.2 8e-07 29.2 0.0 11.2 6 2 7 13 13 13 8 PPR repeat family PPR_3 PF13812.6 ORY43136.1 - 8.2e-19 67.4 1.3 0.00054 20.0 0.0 7.1 4 3 5 9 9 9 7 Pentatricopeptide repeat domain PPR PF01535.20 ORY43136.1 - 2.9e-18 64.8 14.5 0.0014 18.7 0.0 13.9 15 0 0 15 15 15 3 PPR repeat PPR_long PF17177.4 ORY43136.1 - 1e-15 57.7 0.0 1.9e-05 24.1 0.0 4.2 1 1 4 5 5 5 5 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 ORY43136.1 - 3.6e-15 55.4 11.4 0.0003 20.4 0.0 8.5 9 0 0 9 9 9 4 PPR repeat RPM2 PF08579.11 ORY43136.1 - 1.2e-07 32.2 0.1 0.8 10.1 0.0 4.5 4 0 0 4 4 4 3 Mitochondrial ribonuclease P subunit (RPM2) TPR_7 PF13176.6 ORY43136.1 - 0.0018 18.2 0.0 25 5.2 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY43136.1 - 0.0041 17.8 0.7 22 6.2 0.1 6.5 8 2 2 10 10 8 0 Tetratricopeptide repeat U-box PF04564.15 ORY43136.1 - 0.091 12.9 0.0 0.37 11.0 0.0 2.0 1 0 0 1 1 1 0 U-box domain ATP13 PF12921.7 ORY43136.1 - 0.097 12.5 0.2 7.3 6.5 0.0 3.4 3 0 0 3 3 3 0 Mitochondrial ATPase expression TPR_10 PF13374.6 ORY43136.1 - 0.18 11.8 0.0 12 5.9 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Med13_C PF06333.12 ORY43137.1 - 5.1e-14 52.3 0.0 5.1e-14 52.3 0.0 3.8 3 2 0 3 3 3 1 Mediator complex subunit 13 C-terminal domain Cwf_Cwc_15 PF04889.12 ORY43137.1 - 0.12 12.1 0.2 0.22 11.2 0.2 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pkinase PF00069.25 ORY43138.1 - 5.9e-70 235.6 0.0 7.9e-70 235.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY43138.1 - 9.9e-46 156.1 0.0 1.4e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 ORY43138.1 - 2.5e-22 79.0 0.0 6.2e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 ORY43138.1 - 1.2e-07 31.4 0.0 1.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY43138.1 - 1.5e-05 24.0 0.0 2.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY43138.1 - 0.027 14.4 0.1 0.41 10.5 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family DSHCT PF08148.12 ORY43138.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 DSHCT (NUC185) domain JTB PF05439.12 ORY43141.1 - 0.044 13.8 0.0 0.047 13.7 0.0 1.0 1 0 0 1 1 1 0 Jumping translocation breakpoint protein (JTB) Pkinase PF00069.25 ORY43142.1 - 4.6e-66 222.9 0.0 5.9e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY43142.1 - 4.8e-29 101.4 0.0 6.7e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C2 PF00168.30 ORY43142.1 - 1.5e-11 44.5 0.1 2.9e-09 37.1 0.1 2.5 1 1 0 1 1 1 1 C2 domain Pkinase_C PF00433.24 ORY43142.1 - 6.6e-09 36.3 7.2 2e-08 34.8 7.1 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 ORY43142.1 - 0.013 14.9 0.0 0.027 13.8 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Adeno_E3_15_3 PF03307.14 ORY43142.1 - 0.061 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region APH PF01636.23 ORY43142.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 ORY43143.1 - 2.9e-65 220.3 0.0 3.6e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY43143.1 - 3.5e-30 105.1 0.0 4.7e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 ORY43143.1 - 2.3e-09 37.8 7.2 4.8e-09 36.8 7.2 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 ORY43143.1 - 1.1e-08 35.3 0.0 1.7e-05 25.0 0.0 2.4 2 0 0 2 2 2 2 C2 domain Kdo PF06293.14 ORY43143.1 - 0.0076 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY43143.1 - 0.012 15.0 0.0 0.031 13.6 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 ORY43143.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Med21 PF11221.8 ORY43144.1 - 0.0035 17.6 5.5 0.0035 17.6 5.5 3.2 3 1 0 3 3 3 1 Subunit 21 of Mediator complex THOC7 PF05615.13 ORY43144.1 - 0.0076 16.5 1.4 0.0076 16.5 1.4 2.8 1 1 2 3 3 3 1 Tho complex subunit 7 Fam20C PF06702.12 ORY43144.1 - 0.021 14.6 0.4 0.059 13.2 0.4 1.7 1 0 0 1 1 1 0 Golgi casein kinase, C-terminal, Fam20 HIP1_clath_bdg PF16515.5 ORY43144.1 - 0.022 15.4 4.7 0.022 15.4 4.7 3.9 3 1 1 4 4 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Baculo_PEP_C PF04513.12 ORY43144.1 - 0.027 14.5 14.8 0.27 11.3 7.6 3.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus VIR_N PF15912.5 ORY43144.1 - 0.031 13.9 1.4 0.047 13.3 1.4 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal Phage_GP20 PF06810.11 ORY43144.1 - 0.085 12.7 13.5 1.1 9.1 1.1 3.3 2 1 1 3 3 3 0 Phage minor structural protein GP20 SHE3 PF17078.5 ORY43144.1 - 0.2 11.4 23.7 0.061 13.0 2.2 3.2 2 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 DUF3450 PF11932.8 ORY43144.1 - 0.23 10.7 22.0 0.27 10.5 1.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3450) HAUS-augmin3 PF14932.6 ORY43144.1 - 0.3 10.6 25.3 0.032 13.8 2.1 3.1 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 Spc29 PF17082.5 ORY43144.1 - 0.42 10.4 7.7 0.51 10.1 0.7 2.7 2 1 1 3 3 2 0 Spindle Pole Component 29 CLZ PF16526.5 ORY43144.1 - 0.44 10.9 25.6 0.46 10.9 2.5 5.3 3 2 2 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels YkyA PF10368.9 ORY43144.1 - 0.65 9.7 17.7 0.29 10.8 11.0 2.4 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein CENP-Q PF13094.6 ORY43144.1 - 0.86 9.8 25.5 1.6 8.9 3.9 3.6 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Seryl_tRNA_N PF02403.22 ORY43144.1 - 1.2 9.4 11.0 6.6 7.0 0.1 3.3 3 2 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Filament PF00038.21 ORY43144.1 - 1.7 8.1 24.4 3.2 7.2 4.1 3.2 2 1 1 3 3 3 0 Intermediate filament protein Tup_N PF08581.10 ORY43144.1 - 2.3 8.6 21.4 6.6 7.1 2.7 4.2 2 1 2 4 4 4 0 Tup N-terminal DUF5320 PF17253.2 ORY43144.1 - 2.5 9.2 4.5 5.5 8.1 0.0 3.1 3 1 0 3 3 3 0 Family of unknown function (DUF5320) ADIP PF11559.8 ORY43144.1 - 2.6 8.1 22.9 0.73 9.9 0.9 3.5 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Spectrin PF00435.21 ORY43144.1 - 2.8 8.5 19.3 0.92 10.0 1.2 3.7 3 1 0 3 3 3 0 Spectrin repeat APG6_N PF17675.1 ORY43144.1 - 3.1 8.3 25.8 0.81 10.2 3.1 3.4 1 1 2 3 3 3 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 ORY43144.1 - 3.7 7.6 28.4 2 8.5 13.5 3.1 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Ntox28 PF15605.6 ORY43144.1 - 4.1 7.7 9.1 4.2 7.6 0.3 3.2 2 1 0 3 3 3 0 Bacterial toxin 28 ATG16 PF08614.11 ORY43144.1 - 4.8 7.3 31.4 2.8 8.1 10.0 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) MscS_porin PF12795.7 ORY43144.1 - 5.4 6.5 29.0 2.8 7.4 10.5 3.3 2 1 2 4 4 4 0 Mechanosensitive ion channel porin domain COG5 PF10392.9 ORY43144.1 - 6.7 6.9 19.4 1.4 9.1 5.7 3.7 2 2 0 3 3 3 0 Golgi transport complex subunit 5 YabA PF06156.13 ORY43144.1 - 6.8 7.4 20.5 5.3 7.7 1.5 3.8 2 1 1 3 3 3 0 Initiation control protein YabA Sec8_exocyst PF04048.14 ORY43144.1 - 8.2 6.3 20.7 4.4 7.2 4.3 3.9 3 1 1 4 4 4 0 Sec8 exocyst complex component specific domain Arm PF00514.23 ORY43145.1 - 3.4e-89 290.5 18.8 2.7e-13 49.4 0.1 8.9 9 1 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 ORY43145.1 - 1.7e-23 82.9 4.4 3.8e-23 81.7 4.4 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.6 ORY43145.1 - 1.7e-22 79.5 3.2 9.6e-08 32.4 0.1 6.8 6 1 1 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.6 ORY43145.1 - 3.6e-21 75.4 0.2 9.3e-08 32.4 0.0 5.4 3 1 1 5 5 5 3 HEAT repeats HEAT PF02985.22 ORY43145.1 - 3.4e-19 67.3 1.0 4.5e-06 26.5 0.0 7.9 8 0 0 8 8 8 3 HEAT repeat Arm_3 PF16186.5 ORY43145.1 - 1.8e-17 62.6 1.2 1.8e-17 62.6 1.2 2.1 2 0 0 2 2 1 1 Atypical Arm repeat V-ATPase_H_C PF11698.8 ORY43145.1 - 7.3e-08 32.5 0.0 0.084 13.0 0.0 4.6 3 2 2 5 5 5 3 V-ATPase subunit H Arm_2 PF04826.13 ORY43145.1 - 6.8e-07 29.0 0.0 0.024 14.1 0.0 3.2 2 1 1 3 3 3 2 Armadillo-like Cnd1 PF12717.7 ORY43145.1 - 2e-05 24.7 0.1 1.4 9.0 0.0 4.3 3 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 ORY43145.1 - 0.00014 20.6 0.0 0.024 13.2 0.0 3.1 1 1 2 3 3 3 1 Adaptin N terminal region CTNNBL PF08216.11 ORY43145.1 - 0.00095 19.3 0.0 27 5.0 0.0 5.0 5 0 0 5 5 5 0 Catenin-beta-like, Arm-motif containing nuclear HEAT_PBS PF03130.16 ORY43145.1 - 0.0012 19.3 0.9 0.74 10.7 0.1 4.5 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat RICTOR_V PF14668.6 ORY43145.1 - 0.0014 18.8 1.0 0.39 11.0 0.0 4.4 4 1 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Atx10homo_assoc PF09759.9 ORY43145.1 - 0.012 15.6 0.1 5.6 7.1 0.0 4.1 5 0 0 5 5 4 0 Spinocerebellar ataxia type 10 protein domain TFIIE-A_C PF11521.8 ORY43145.1 - 0.31 11.4 2.4 0.71 10.2 2.4 1.6 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha Phytochelatin PF05023.14 ORY43146.1 - 1.6e-13 50.4 0.0 1.9e-10 40.3 0.0 2.3 2 0 0 2 2 2 2 Phytochelatin synthase Peptidase_C39_2 PF13529.6 ORY43146.1 - 0.06 13.9 0.1 1.7 9.2 0.1 2.3 1 1 0 1 1 1 0 Peptidase_C39 like family EMC3_TMCO1 PF01956.16 ORY43147.1 - 1.7e-41 141.8 3.2 2.3e-41 141.3 3.2 1.2 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like HMG_box PF00505.19 ORY43149.1 - 7.2e-14 52.0 0.6 1.5e-13 51.0 0.6 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY43149.1 - 0.0026 18.3 1.3 0.0045 17.6 1.3 1.4 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 ORY43150.1 - 4.8e-07 30.1 0.2 8.7e-07 29.3 0.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY43150.1 - 0.09 13.4 0.5 0.19 12.4 0.5 1.5 1 0 0 1 1 1 0 HMG-box domain MATalpha_HMGbox PF04769.12 ORY43150.1 - 0.16 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box F-box-like PF12937.7 ORY43151.1 - 0.002 17.9 0.4 0.0072 16.2 0.4 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY43151.1 - 0.066 13.1 0.1 0.22 11.5 0.1 2.0 1 1 0 1 1 1 0 F-box domain HSP20 PF00011.21 ORY43152.1 - 2.8e-06 27.4 0.2 6.1e-05 23.1 0.2 2.2 1 1 0 1 1 1 1 Hsp20/alpha crystallin family DUF1455 PF07306.11 ORY43152.1 - 0.0094 15.9 2.4 0.033 14.2 1.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1455) ArsA_HSP20 PF17886.1 ORY43152.1 - 0.054 13.1 0.1 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 HSP20-like domain found in ArsA CTNNB1_binding PF08347.11 ORY43152.1 - 0.058 13.6 1.6 0.08 13.1 1.6 1.2 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Sporozoite_P67 PF05642.11 ORY43153.1 - 0.11 10.5 2.8 0.13 10.4 2.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.12 ORY43153.1 - 1.1 8.5 10.2 1.3 8.3 10.2 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 ORY43153.1 - 5.3 5.0 13.8 7.8 4.5 13.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi HSP20 PF00011.21 ORY43154.1 - 1.4e-06 28.4 0.4 4.2e-05 23.6 0.4 2.2 1 1 0 1 1 1 1 Hsp20/alpha crystallin family Svf1_C PF17187.4 ORY43155.1 - 5.7e-31 107.6 0.1 8.5e-31 107.0 0.1 1.3 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 ORY43155.1 - 1.1e-21 77.5 0.0 2e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain VWA_N PF08399.11 ORY43155.1 - 0.022 15.2 0.1 4.3 7.8 0.0 2.3 2 0 0 2 2 2 0 VWA N-terminal PBP-Tp47_c PF14888.6 ORY43155.1 - 0.038 13.9 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain C DUF5038 PF16441.5 ORY43155.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF5038) CEP76-C2 PF15627.6 ORY43157.1 - 7.5e-22 77.6 0.1 1.3e-21 76.8 0.1 1.4 1 0 0 1 1 1 1 CEP76 C2 domain C2-C2_1 PF11618.8 ORY43157.1 - 0.14 12.2 0.0 0.4 10.8 0.0 1.7 2 0 0 2 2 2 0 First C2 domain of RPGR-interacting protein 1 Peptidase_M1 PF01433.20 ORY43158.1 - 4.3e-44 150.7 1.9 3.5e-41 141.2 2.2 2.7 2 1 0 2 2 2 2 Peptidase family M1 domain Peptidase_M1_N PF17900.1 ORY43158.1 - 1.6e-31 109.9 0.0 1.2e-29 103.8 0.0 2.6 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 ORY43158.1 - 1.1e-22 81.0 0.0 2e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain HSP20 PF00011.21 ORY43159.1 - 1.7e-06 28.1 0.4 5.1e-05 23.4 0.4 2.2 1 1 0 1 1 1 1 Hsp20/alpha crystallin family Cwf_Cwc_15 PF04889.12 ORY43160.1 - 0.43 10.3 8.7 0.57 9.9 8.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3439 PF11921.8 ORY43160.1 - 0.48 10.4 4.6 0.8 9.7 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) NOA36 PF06524.12 ORY43160.1 - 2.4 7.4 11.0 3.1 7.0 11.0 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 ORY43160.1 - 4.4 5.4 8.1 6 4.9 8.1 1.2 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.11 ORY43160.1 - 4.6 5.2 11.1 0.17 9.9 2.2 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen HSP20 PF00011.21 ORY43161.1 - 1.8e-07 31.2 0.4 3.8e-06 27.0 0.4 2.2 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORY43161.1 - 0.016 14.8 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 HSP20-like domain found in ArsA CTNNB1_binding PF08347.11 ORY43161.1 - 0.047 13.9 1.1 0.065 13.4 1.1 1.2 1 0 0 1 1 1 0 N-terminal CTNNB1 binding DUF1455 PF07306.11 ORY43161.1 - 0.14 12.2 2.1 0.47 10.4 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1455) F-box-like PF12937.7 ORY43162.1 - 0.00075 19.3 0.9 0.0022 17.8 0.9 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY43162.1 - 0.049 13.5 0.1 0.13 12.2 0.1 1.7 1 0 0 1 1 1 0 F-box domain FMN_dh PF01070.18 ORY43163.1 - 1e-129 432.5 0.3 1.2e-129 432.3 0.3 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ORY43163.1 - 4e-09 35.9 0.1 1.7e-07 30.6 0.0 2.4 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 ORY43163.1 - 1.5e-06 27.9 0.2 4.5e-06 26.3 0.1 1.8 2 0 0 2 2 2 1 Nitronate monooxygenase Glu_synthase PF01645.17 ORY43163.1 - 0.00014 21.1 0.0 0.00028 20.1 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.14 ORY43163.1 - 0.04 13.2 0.1 4.8 6.4 0.0 2.9 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG STAT2_C PF12188.8 ORY43163.1 - 0.063 13.2 0.0 0.25 11.3 0.0 2.0 2 0 0 2 2 2 0 Signal transducer and activator of transcription 2 C terminal G3P_antiterm PF04309.12 ORY43163.1 - 0.11 11.9 0.0 0.28 10.6 0.0 1.7 1 1 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator SOG2 PF10428.9 ORY43164.1 - 7.1 5.7 10.1 9 5.4 10.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein LapA_dom PF06305.11 ORY43166.1 - 0.75 9.7 0.0 0.75 9.7 0.0 2.5 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Arrestin_N PF00339.29 ORY43167.1 - 0.094 12.8 0.2 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain MAP65_ASE1 PF03999.12 ORY43167.1 - 5.9 5.5 9.3 8.6 4.9 9.3 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Sec7 PF01369.20 ORY43168.1 - 1.3e-69 233.5 1.3 2.4e-69 232.7 0.1 2.1 2 0 0 2 2 2 1 Sec7 domain DUF1981 PF09324.10 ORY43168.1 - 3.1e-23 81.4 7.7 5.4e-19 67.8 0.2 5.6 5 0 0 5 5 5 3 Domain of unknown function (DUF1981) adh_short PF00106.25 ORY43169.1 - 6.3e-09 35.6 0.0 9.3e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY43169.1 - 0.00015 21.8 0.0 0.00023 21.1 0.0 1.3 1 0 0 1 1 1 1 KR domain WEMBL PF05701.11 ORY43170.1 - 0.08 11.6 6.9 0.11 11.2 6.9 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light G-alpha PF00503.20 ORY43170.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit DUF3138 PF11336.8 ORY43170.1 - 0.29 9.7 4.2 0.45 9.1 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) ZapB PF06005.12 ORY43170.1 - 0.38 11.2 1.3 0.77 10.2 1.3 1.4 1 0 0 1 1 1 0 Cell division protein ZapB LPP PF04728.13 ORY43170.1 - 1.8 9.0 10.7 0.086 13.2 2.8 2.5 1 1 1 2 2 2 0 Lipoprotein leucine-zipper zf-C2H2_4 PF13894.6 ORY43171.1 - 1.5e-07 31.6 6.1 0.0072 17.1 0.1 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY43171.1 - 0.001 19.0 1.0 0.88 9.6 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY43171.1 - 0.0028 18.0 5.8 0.04 14.4 0.1 3.5 3 0 0 3 3 3 1 Zinc finger, C2H2 type Zn-ribbon_8 PF09723.10 ORY43171.1 - 0.0066 16.5 4.5 0.69 10.1 0.7 2.7 2 0 0 2 2 2 2 Zinc ribbon domain XPA_N PF01286.18 ORY43171.1 - 0.063 13.3 1.0 6.5 6.9 0.0 2.5 2 0 0 2 2 2 0 XPA protein N-terminal zinc_ribbon_9 PF14369.6 ORY43171.1 - 0.11 12.7 2.9 1.1 9.6 0.8 2.7 2 0 0 2 2 2 0 zinc-ribbon zf-C2H2_11 PF16622.5 ORY43171.1 - 0.16 11.8 0.9 25 4.8 0.1 2.9 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HE PF16278.5 ORY43171.1 - 0.37 11.3 2.0 16 6.0 0.1 2.7 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-TFIIB PF13453.6 ORY43171.1 - 0.37 10.2 4.2 9.2 5.7 0.2 2.7 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-BED PF02892.15 ORY43171.1 - 0.5 10.4 4.1 0.62 10.1 0.1 2.5 2 1 0 2 2 2 0 BED zinc finger zf-Di19 PF05605.12 ORY43171.1 - 7.8 6.9 7.1 1 9.7 1.5 2.2 2 1 1 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 ORY43172.1 - 4.9e-07 30.0 7.8 0.007 17.1 0.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY43172.1 - 0.001 19.0 1.0 0.86 9.7 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY43172.1 - 0.0027 18.1 5.8 0.039 14.4 0.1 3.5 3 0 0 3 3 3 1 Zinc finger, C2H2 type Zn-ribbon_8 PF09723.10 ORY43172.1 - 0.0068 16.5 4.4 0.66 10.1 0.7 2.5 2 0 0 2 2 2 2 Zinc ribbon domain XPA_N PF01286.18 ORY43172.1 - 0.064 13.3 1.0 6.3 6.9 0.0 2.4 2 0 0 2 2 2 0 XPA protein N-terminal zinc_ribbon_9 PF14369.6 ORY43172.1 - 0.12 12.7 2.9 1.1 9.6 0.8 2.7 2 0 0 2 2 2 0 zinc-ribbon zf-C2H2_11 PF16622.5 ORY43172.1 - 0.15 11.8 0.9 24 4.8 0.1 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-TFIIB PF13453.6 ORY43172.1 - 0.16 11.3 2.4 9 5.7 0.2 2.6 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-C2HE PF16278.5 ORY43172.1 - 0.38 11.2 1.7 18 5.9 0.1 2.6 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-BED PF02892.15 ORY43172.1 - 0.59 10.2 4.3 0.6 10.2 0.1 2.5 2 1 0 2 2 2 0 BED zinc finger zinc_ribbon_5 PF13719.6 ORY43172.1 - 2.6 7.9 4.4 4.7 7.1 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-Di19 PF05605.12 ORY43172.1 - 6.6 7.1 6.9 0.86 9.9 1.3 2.3 2 1 1 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding ACC_central PF08326.12 ORY43173.1 - 2.9e-195 650.7 0.0 3.6e-195 650.4 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 ORY43173.1 - 4.7e-171 569.8 0.0 6.7e-171 569.3 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 ORY43173.1 - 4.6e-55 186.4 1.5 2e-54 184.3 0.1 2.4 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ORY43173.1 - 6e-30 104.0 0.1 1.4e-29 102.9 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORY43173.1 - 2.2e-21 76.0 0.0 9.7e-21 73.9 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ORY43173.1 - 2.1e-12 46.7 0.0 1.3e-11 44.2 0.0 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 ORY43173.1 - 5e-06 26.6 0.0 4.1e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ORY43173.1 - 0.00057 19.5 0.0 0.0015 18.2 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 ORY43173.1 - 0.013 15.3 0.0 0.069 13.0 0.0 2.1 2 0 0 2 2 2 0 Biotin-lipoyl like RimK PF08443.11 ORY43173.1 - 0.075 12.6 0.0 0.27 10.8 0.0 1.9 1 1 0 1 1 1 0 RimK-like ATP-grasp domain ACC_central PF08326.12 ORY43174.1 - 2.9e-195 650.7 0.0 3.6e-195 650.4 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 ORY43174.1 - 4.7e-171 569.8 0.0 6.7e-171 569.3 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 ORY43174.1 - 4.6e-55 186.4 1.5 2e-54 184.3 0.1 2.4 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ORY43174.1 - 6e-30 104.0 0.1 1.4e-29 102.9 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORY43174.1 - 2.2e-21 76.0 0.0 9.7e-21 73.9 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ORY43174.1 - 2.1e-12 46.7 0.0 1.3e-11 44.2 0.0 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 ORY43174.1 - 5e-06 26.6 0.0 4.1e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ORY43174.1 - 0.00057 19.5 0.0 0.0015 18.2 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 ORY43174.1 - 0.013 15.3 0.0 0.069 13.0 0.0 2.1 2 0 0 2 2 2 0 Biotin-lipoyl like RimK PF08443.11 ORY43174.1 - 0.075 12.6 0.0 0.27 10.8 0.0 1.9 1 1 0 1 1 1 0 RimK-like ATP-grasp domain zf-C2H2_4 PF13894.6 ORY43175.1 - 7.1e-05 23.3 14.4 0.02 15.7 0.6 4.0 4 0 0 4 4 3 2 C2H2-type zinc finger UPF0547 PF10571.9 ORY43175.1 - 0.0014 18.6 8.0 0.012 15.7 0.1 3.0 3 0 0 3 3 2 1 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.6 ORY43175.1 - 0.0047 16.3 2.4 0.86 9.1 0.1 2.7 2 0 0 2 2 2 1 zinc-ribbon domain zf-C2H2_6 PF13912.6 ORY43175.1 - 0.0078 16.2 5.0 0.96 9.5 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-FPG_IleRS PF06827.14 ORY43175.1 - 0.01 15.7 0.7 2.3 8.2 0.1 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS A2L_zn_ribbon PF08792.10 ORY43175.1 - 0.012 15.3 2.8 2.7 7.8 0.5 2.6 2 0 0 2 2 2 0 A2L zinc ribbon domain zf_UBZ PF18439.1 ORY43175.1 - 0.014 15.0 1.3 2.5 7.8 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger TF_Zn_Ribbon PF08271.12 ORY43175.1 - 0.025 14.1 3.2 2 8.0 0.1 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding YhfH PF14149.6 ORY43175.1 - 0.039 13.9 0.7 12 6.0 0.1 2.8 2 0 0 2 2 2 0 YhfH-like protein Zn-ribbon_8 PF09723.10 ORY43175.1 - 0.039 14.1 8.8 1.7 8.8 0.5 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2H2 PF00096.26 ORY43175.1 - 0.075 13.5 0.3 0.075 13.5 0.3 4.1 4 0 0 4 4 3 0 Zinc finger, C2H2 type XPA_N PF01286.18 ORY43175.1 - 0.076 13.1 2.5 3 8.0 0.2 2.5 2 0 0 2 2 2 0 XPA protein N-terminal ADK_lid PF05191.14 ORY43175.1 - 0.078 13.0 1.9 6.6 6.8 0.1 2.8 3 0 0 3 3 3 0 Adenylate kinase, active site lid zf-tcix PF14952.6 ORY43175.1 - 0.08 12.6 7.7 0.086 12.5 0.3 3.3 3 0 0 3 3 3 0 Putative treble-clef, zinc-finger, Zn-binding zf-C4_Topoisom PF01396.19 ORY43175.1 - 0.097 12.5 1.6 9.6 6.1 0.1 2.5 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger zf-NADH-PPase PF09297.11 ORY43175.1 - 0.11 12.2 1.1 7.1 6.4 0.1 2.7 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 ORY43175.1 - 0.13 12.1 3.9 4.9 7.0 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_9 PF14369.6 ORY43175.1 - 0.15 12.4 5.1 3.6 7.9 0.5 3.2 3 0 0 3 3 3 0 zinc-ribbon Zn-C2H2_12 PF18112.1 ORY43175.1 - 0.26 11.8 7.9 0.98 9.9 0.2 3.2 3 0 0 3 3 2 0 Autophagy receptor zinc finger-C2H2 domain zf-Di19 PF05605.12 ORY43175.1 - 0.37 11.1 6.2 9.2 6.7 1.7 2.9 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_5 PF13719.6 ORY43175.1 - 0.45 10.3 5.0 8 6.3 0.6 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 ORY43175.1 - 0.47 10.4 3.2 5.5 7.0 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-ACC PF17848.1 ORY43175.1 - 0.5 10.5 4.7 2.1 8.5 0.1 2.5 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Zn_Tnp_IS1595 PF12760.7 ORY43175.1 - 0.62 10.1 8.2 0.47 10.5 0.5 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.7 ORY43175.1 - 0.79 9.8 6.6 10 6.2 6.6 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_11 PF16622.5 ORY43175.1 - 2 8.3 10.5 0.76 9.6 0.4 3.0 3 0 0 3 3 2 0 zinc-finger C2H2-type DUF35_N PF12172.8 ORY43175.1 - 2.5 8.0 8.7 4.8 7.2 0.1 3.0 3 0 0 3 3 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Zn_Tnp_IS91 PF14319.6 ORY43175.1 - 4.7 7.3 7.5 15 5.7 1.3 2.4 1 1 0 2 2 2 0 Transposase zinc-binding domain zf-TFIIB PF13453.6 ORY43175.1 - 4.9 6.6 6.3 16 5.0 0.3 2.6 2 1 0 2 2 2 0 Transcription factor zinc-finger zf_C2HC_14 PF18574.1 ORY43175.1 - 5 7.0 5.2 19 5.1 0.6 2.6 2 0 0 2 2 2 0 C2HC Zing finger domain Glyco_hydro_16 PF00722.21 ORY43176.1 - 3.4e-09 36.4 1.0 6.9e-09 35.4 0.4 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 DUF347 PF03988.12 ORY43177.1 - 2.5 8.4 6.8 26 5.1 6.8 2.2 1 1 0 1 1 1 0 Repeat of Unknown Function (DUF347) DUF3450 PF11932.8 ORY43178.1 - 0.00036 19.9 1.5 0.00044 19.6 1.2 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) Nsp1_C PF05064.13 ORY43178.1 - 0.001 18.8 1.2 0.0011 18.7 1.2 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region ZapB PF06005.12 ORY43178.1 - 0.0018 18.7 5.1 0.0025 18.2 5.1 1.3 1 1 0 1 1 1 1 Cell division protein ZapB BLOC1_2 PF10046.9 ORY43178.1 - 0.0021 18.3 1.1 0.0027 17.9 1.1 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 ORY43178.1 - 0.0031 17.4 0.9 0.0035 17.2 0.9 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 BST2 PF16716.5 ORY43178.1 - 0.0038 17.8 2.3 0.0049 17.4 2.3 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 GAS PF13851.6 ORY43178.1 - 0.0039 16.6 2.9 0.0044 16.4 2.9 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 ORY43178.1 - 0.017 15.1 2.0 0.017 15.1 2.0 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Cluap1 PF10234.9 ORY43178.1 - 0.018 14.4 1.5 0.019 14.4 1.5 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Tropomyosin_1 PF12718.7 ORY43178.1 - 0.024 14.8 2.5 0.036 14.2 2.5 1.4 1 1 0 1 1 1 0 Tropomyosin like YabA PF06156.13 ORY43178.1 - 0.026 15.1 1.3 0.031 14.9 1.3 1.2 1 0 0 1 1 1 0 Initiation control protein YabA HlyD_D23 PF16576.5 ORY43178.1 - 0.028 13.6 1.0 0.03 13.5 1.0 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Herpes_UL6 PF01763.16 ORY43178.1 - 0.028 12.9 1.7 0.029 12.9 1.7 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like BSP PF04450.12 ORY43178.1 - 0.034 14.0 0.0 0.053 13.3 0.0 1.3 1 1 0 1 1 1 0 Peptidase of plants and bacteria Rab_bind PF16704.5 ORY43178.1 - 0.035 14.1 0.3 2.8 8.1 0.1 2.3 1 1 1 2 2 2 0 Rab binding domain DUF948 PF06103.11 ORY43178.1 - 0.041 14.1 0.5 0.058 13.7 0.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 ORY43178.1 - 0.042 14.4 2.8 0.057 14.0 2.8 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 ORY43178.1 - 0.12 13.0 4.7 0.33 11.6 4.7 1.8 1 1 0 1 1 1 0 SlyX Cep57_MT_bd PF06657.13 ORY43178.1 - 0.13 12.7 3.5 1.7 9.2 0.8 2.2 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 XhlA PF10779.9 ORY43178.1 - 0.14 12.3 2.3 0.29 11.4 2.3 1.5 1 0 0 1 1 1 0 Haemolysin XhlA Fib_alpha PF08702.10 ORY43178.1 - 0.15 12.2 3.3 0.49 10.6 3.2 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 ORY43178.1 - 0.25 11.8 2.6 1.1 9.8 2.9 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 ORY43178.1 - 0.62 9.9 5.3 6.3 6.7 0.4 2.0 1 1 1 2 2 2 0 Septum formation initiator Neural_ProG_Cyt PF06567.11 ORY43180.1 - 0.00011 22.4 0.3 1.2 9.4 0.1 3.0 1 1 1 2 2 2 2 Neural chondroitin sulphate proteoglycan cytoplasmic domain MRP-S24 PF14955.6 ORY43180.1 - 0.0011 18.9 0.0 8.4 6.4 0.0 3.0 1 1 2 3 3 3 2 Mitochondrial ribosome subunit S24 ARTD15_N PF18084.1 ORY43180.1 - 0.0026 18.0 0.1 2.7 8.3 0.0 2.5 1 1 1 2 2 2 2 ARTD15 N-terminal domain PAP2_3 PF14378.6 ORY43180.1 - 0.032 13.9 0.2 6.9 6.3 0.0 2.1 1 1 1 2 2 2 0 PAP2 superfamily Peptidase_C53 PF05550.11 ORY43180.1 - 0.051 13.3 0.1 58 3.3 0.0 3.0 3 0 0 3 3 3 0 Pestivirus Npro endopeptidase C53 Lantibiotic_a PF14867.6 ORY43180.1 - 0.063 13.0 0.0 78 3.1 0.0 3.1 3 0 0 3 3 3 0 Lantibiotic alpha DUF1798 PF08807.10 ORY43180.1 - 0.072 13.2 0.0 28 4.9 0.0 2.8 1 1 2 3 3 3 0 Bacterial domain of unknown function (DUF1798) HrpB7 PF09486.10 ORY43180.1 - 0.1 13.0 0.3 8.2 6.8 0.1 2.2 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) PAF PF15715.5 ORY43182.1 - 1.8 9.1 3.9 3 8.4 3.9 1.3 1 0 0 1 1 1 0 PCNA-associated factor histone like domain Dynactin_p62 PF05502.13 ORY43262.1 - 0.12 11.1 0.1 0.13 11.0 0.1 1.1 1 0 0 1 1 1 0 Dynactin p62 family Abhydrolase_1 PF00561.20 ORY43265.1 - 9.1e-24 84.5 0.1 7.2e-22 78.3 0.2 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 ORY43265.1 - 2.3e-23 82.3 0.0 4.2e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein TPR_1 PF00515.28 ORY43266.1 - 2.3e-69 226.6 60.9 3e-07 30.0 2.0 23.2 23 1 0 23 23 23 14 Tetratricopeptide repeat TPR_11 PF13414.6 ORY43266.1 - 2.1e-52 174.5 38.4 8.8e-06 25.3 0.1 18.6 13 5 6 19 19 18 14 TPR repeat TPR_2 PF07719.17 ORY43266.1 - 6.3e-52 169.6 42.7 1.1e-05 25.1 2.1 22.4 22 0 0 22 22 22 12 Tetratricopeptide repeat TPR_17 PF13431.6 ORY43266.1 - 4.3e-38 127.0 32.8 0.0021 18.3 0.0 18.5 19 0 0 19 19 18 10 Tetratricopeptide repeat TPR_9 PF13371.6 ORY43266.1 - 6.2e-34 116.0 16.7 0.00019 21.5 0.1 13.4 8 2 4 14 14 14 6 Tetratricopeptide repeat TPR_16 PF13432.6 ORY43266.1 - 1.8e-32 111.7 17.9 0.027 15.1 0.0 12.4 12 1 1 13 13 13 9 Tetratricopeptide repeat TPR_8 PF13181.6 ORY43266.1 - 3.5e-28 95.4 41.3 0.0026 17.8 0.1 17.2 20 0 0 20 20 16 7 Tetratricopeptide repeat TPR_12 PF13424.6 ORY43266.1 - 1.2e-21 76.7 32.9 0.0035 17.6 0.0 13.5 10 4 4 14 14 14 6 Tetratricopeptide repeat Nitroreductase PF00881.24 ORY43266.1 - 6.4e-17 62.1 0.0 4.1e-16 59.5 0.0 2.4 2 0 0 2 2 2 1 Nitroreductase family TPR_14 PF13428.6 ORY43266.1 - 6.8e-15 54.5 23.5 0.16 12.9 0.3 13.1 11 2 4 15 15 14 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY43266.1 - 3.7e-11 43.4 28.8 0.14 12.7 0.1 11.8 11 3 2 13 13 11 4 Tetratricopeptide repeat TPR_7 PF13176.6 ORY43266.1 - 1.1e-09 37.7 24.9 0.45 10.7 0.3 11.6 13 0 0 13 13 11 2 Tetratricopeptide repeat NARP1 PF12569.8 ORY43266.1 - 1.3e-09 37.5 1.7 1.9 7.3 0.0 6.8 6 1 1 7 7 7 4 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 ORY43266.1 - 1.4e-09 38.0 39.9 0.69 10.7 0.4 14.7 16 1 0 16 16 15 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY43266.1 - 0.0015 18.7 34.4 2.6 8.3 0.3 9.1 9 1 1 10 10 10 2 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 ORY43266.1 - 0.0017 18.8 0.4 0.48 10.8 0.0 4.8 6 1 1 7 7 7 1 Bacterial transcriptional activator domain TPR_MalT PF17874.1 ORY43266.1 - 0.0021 17.5 0.6 0.32 10.3 0.0 3.4 4 0 0 4 4 4 1 MalT-like TPR region Fis1_TPR_C PF14853.6 ORY43266.1 - 7.5 6.7 11.7 6.1 7.0 0.1 6.0 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat Glyco_hydro_26 PF02156.15 ORY43267.1 - 1.4e-06 27.9 0.4 8e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 EF-hand_5 PF13202.6 ORY43267.1 - 0.17 11.4 0.1 0.4 10.3 0.1 1.6 1 0 0 1 1 1 0 EF hand Asp PF00026.23 ORY43268.1 - 8.7e-61 206.1 7.6 1.4e-60 205.3 7.6 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY43268.1 - 0.00053 20.3 9.6 0.036 14.3 0.1 3.8 3 1 1 4 4 4 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY43268.1 - 0.0023 17.7 0.0 0.006 16.4 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 ORY43268.1 - 0.0029 18.2 1.9 1.2 9.9 0.2 2.9 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 ORY43268.1 - 0.16 12.6 0.5 6.5 7.4 0.1 2.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Ank_2 PF12796.7 ORY43269.1 - 3.6e-17 62.7 0.0 3.4e-10 40.4 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY43269.1 - 4.6e-14 51.1 0.0 0.039 14.5 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 ORY43269.1 - 2e-11 44.2 0.3 0.045 14.4 0.0 5.2 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY43269.1 - 2.8e-09 37.1 0.2 0.081 13.3 0.0 4.8 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY43269.1 - 6.2e-09 35.9 0.0 0.032 14.7 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ion_trans PF00520.31 ORY43269.1 - 0.0012 18.1 23.2 0.0034 16.6 22.5 1.9 1 1 0 1 1 1 1 Ion transport protein RD3 PF14473.6 ORY43269.1 - 0.1 12.4 1.5 0.27 11.1 1.5 1.6 1 0 0 1 1 1 0 RD3 protein Ank_2 PF12796.7 ORY43270.1 - 5.4e-14 52.5 0.0 1.5e-06 28.7 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY43270.1 - 7.7e-13 47.4 0.3 0.032 14.7 0.0 5.6 4 1 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 ORY43270.1 - 3.3e-09 37.1 0.8 0.0095 16.5 0.1 5.0 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY43270.1 - 2.2e-08 34.2 1.1 0.027 14.8 0.0 4.9 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY43270.1 - 6.2e-07 29.6 0.1 0.17 12.4 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ion_trans PF00520.31 ORY43270.1 - 1.6e-05 24.3 14.6 2.3e-05 23.8 14.6 1.2 1 0 0 1 1 1 1 Ion transport protein Methyltransf_4 PF02390.17 ORY43270.1 - 0.025 14.0 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase F-box-like PF12937.7 ORY43271.1 - 0.015 15.2 2.8 0.028 14.3 0.3 2.3 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 ORY43271.1 - 0.078 12.9 0.6 0.81 9.6 0.2 2.6 2 0 0 2 2 2 0 F-box domain Arm PF00514.23 ORY43278.1 - 0.0017 18.3 10.0 0.47 10.6 0.1 5.7 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Thioredoxin PF00085.20 ORY43279.1 - 7.5e-28 96.5 0.0 1.2e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 ORY43279.1 - 2.1e-06 27.3 0.0 2.5e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 ORY43279.1 - 4.3e-06 26.5 0.0 5.7e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY43279.1 - 5.1e-05 23.7 0.3 0.0014 19.0 0.3 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORY43279.1 - 0.00021 21.5 0.0 0.0023 18.2 0.0 2.0 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.6 ORY43279.1 - 0.00063 19.9 0.0 0.00098 19.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 ORY43279.1 - 0.0023 17.9 0.0 0.0037 17.2 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Phosducin PF02114.16 ORY43279.1 - 0.0025 16.8 0.0 0.0026 16.7 0.0 1.1 1 0 0 1 1 1 1 Phosducin TPR_1 PF00515.28 ORY43279.1 - 0.0073 16.1 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY43279.1 - 0.031 14.4 0.0 0.071 13.3 0.0 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat HyaE PF07449.11 ORY43279.1 - 0.051 13.5 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 ORY43279.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin DSBA PF01323.20 ORY43279.1 - 0.14 11.9 0.2 3.8 7.3 0.0 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain STI1 PF17830.1 ORY43280.1 - 2.2e-32 110.8 11.3 2.8e-21 75.2 1.7 2.9 2 0 0 2 2 2 2 STI1 domain TPR_1 PF00515.28 ORY43280.1 - 3.7e-30 102.5 21.5 1.7e-05 24.5 0.0 7.6 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 ORY43280.1 - 2.1e-22 77.4 21.8 0.0015 18.5 0.3 7.4 8 0 0 8 8 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 ORY43280.1 - 4.2e-17 61.6 13.8 7.1e-05 22.4 0.1 6.1 5 1 1 6 6 6 4 TPR repeat TPR_8 PF13181.6 ORY43280.1 - 4.5e-12 45.2 26.0 4.7e-05 23.3 0.3 7.5 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 ORY43280.1 - 2.2e-11 44.1 13.8 0.0022 18.5 0.0 6.2 6 2 1 7 7 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORY43280.1 - 8.5e-11 42.0 18.3 4.1e-08 33.4 0.0 6.1 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY43280.1 - 9.8e-11 41.6 4.6 1.3 10.1 0.2 7.2 5 3 2 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY43280.1 - 1.1e-10 40.7 3.5 5.9e-05 22.8 0.0 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY43280.1 - 8e-08 32.2 10.0 0.39 11.2 0.0 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY43280.1 - 2e-06 28.3 8.7 0.15 12.7 0.0 5.4 4 2 1 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY43280.1 - 1.6e-05 25.1 7.6 0.018 15.3 0.7 3.8 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 ORY43280.1 - 0.0022 17.8 17.3 0.92 9.5 0.0 6.7 8 0 0 8 8 8 2 Tetratricopeptide repeat DUF627 PF04781.12 ORY43280.1 - 0.1 12.6 3.6 3.1 7.8 0.1 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF627) TPR_6 PF13174.6 ORY43280.1 - 1.3 9.8 7.8 31 5.5 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 ORY43280.1 - 1.3 9.4 6.7 20 5.7 0.1 4.0 4 0 0 4 4 2 0 PPR repeat DUF3856 PF12968.7 ORY43280.1 - 4.5 7.3 8.7 4.3 7.4 0.5 3.5 4 0 0 4 4 4 0 Domain of Unknown Function (DUF3856) 7tm_2 PF00002.24 ORY43282.1 - 2.8e-11 43.2 9.9 4.5e-11 42.5 9.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 ORY43282.1 - 7.1e-08 32.1 9.7 8.9e-08 31.8 9.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 ORY43282.1 - 1.6e-06 28.1 12.9 2.5e-06 27.4 12.9 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 ORY43282.1 - 0.005 16.0 14.9 0.011 14.9 14.6 1.6 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 ORY43283.1 - 2.5e-12 46.7 4.6 3.1e-12 46.4 4.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 ORY43283.1 - 1e-11 44.6 7.3 1.6e-11 44.0 7.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Git3 PF11710.8 ORY43283.1 - 2e-09 37.6 15.0 3.3e-09 36.8 15.0 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 HLH PF00010.26 ORY43284.1 - 3.3e-08 33.4 0.0 6.4e-08 32.4 0.0 1.5 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Sporozoite_P67 PF05642.11 ORY43284.1 - 1.4 6.9 4.8 1.6 6.7 4.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Diphthami_syn_2 PF01902.17 ORY43286.1 - 2.3e-11 43.7 0.0 3.3e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 Diphthamide synthase Ribosomal_60s PF00428.19 ORY43287.1 - 1.2 9.8 5.3 0.57 10.8 0.0 3.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein 7tm_2 PF00002.24 ORY43288.1 - 1.4e-12 47.4 7.8 2.3e-12 46.8 7.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 ORY43288.1 - 1.1e-08 34.6 13.1 1.3e-06 27.8 9.1 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 ORY43288.1 - 2.3e-08 33.7 7.6 3.1e-08 33.3 7.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 ORY43288.1 - 4.4e-07 29.9 10.5 1.3e-06 28.4 10.5 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 DUF1182 PF06681.13 ORY43288.1 - 0.12 12.0 5.1 0.22 11.1 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1182) Sigma_reg_N PF13800.6 ORY43288.1 - 0.71 10.2 3.2 25 5.2 0.2 2.6 2 0 0 2 2 2 0 Sigma factor regulator N-terminal RhodobacterPufX PF11511.8 ORY43288.1 - 9 6.0 6.6 1.1 8.9 0.4 2.6 3 0 0 3 3 3 0 Intrinsic membrane protein PufX 7tm_2 PF00002.24 ORY43289.1 - 1.6e-08 34.2 10.6 1.8e-08 34.0 10.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 ORY43289.1 - 0.0003 20.2 9.9 0.00039 19.8 9.9 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 ORY43289.1 - 0.0006 19.0 9.7 0.00069 18.8 9.7 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.8 ORY43289.1 - 0.0018 18.1 10.9 0.0034 17.2 10.9 1.4 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GLE1 PF07817.13 ORY43292.1 - 9.3e-64 215.0 1.4 1.9e-63 214.0 1.4 1.5 1 0 0 1 1 1 1 GLE1-like protein AAA_15 PF13175.6 ORY43292.1 - 0.0024 17.7 3.0 0.0035 17.1 3.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain V_ATPase_I PF01496.19 ORY43292.1 - 0.064 11.2 3.8 0.095 10.6 3.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.6 ORY43292.1 - 0.08 12.3 12.8 0.13 11.6 12.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rrn6 PF10214.9 ORY43292.1 - 0.51 8.8 9.4 0.7 8.3 9.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SOBP PF15279.6 ORY43292.1 - 0.79 10.3 13.9 1.2 9.7 13.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein AAA_23 PF13476.6 ORY43292.1 - 1.6 9.2 17.1 2.7 8.4 17.1 1.4 1 0 0 1 1 1 0 AAA domain Borrelia_P83 PF05262.11 ORY43292.1 - 1.9 6.9 21.0 2.9 6.3 21.0 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Presenilin PF01080.17 ORY43292.1 - 4.2 6.0 10.1 7.4 5.2 10.1 1.4 1 0 0 1 1 1 0 Presenilin 7tm_2 PF00002.24 ORY43293.1 - 1.8e-10 40.5 11.8 2.7e-10 40.0 11.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 ORY43293.1 - 6.6e-08 32.2 0.1 8.4e-08 31.9 0.1 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Frizzled PF01534.17 ORY43293.1 - 0.00081 18.5 10.1 0.00081 18.5 10.1 2.1 2 1 1 3 3 3 2 Frizzled/Smoothened family membrane region Git3 PF11710.8 ORY43293.1 - 0.12 12.1 10.3 0.2 11.4 10.3 1.3 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Ribosomal_L4 PF00573.22 ORY43294.1 - 2.2e-39 135.2 0.8 3.2e-39 134.6 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 ORY43294.1 - 1.5e-30 105.1 1.5 1.1e-27 95.9 0.2 2.5 2 0 0 2 2 2 2 60S ribosomal protein L4 C-terminal domain WSC PF01822.19 ORY43296.1 - 9.9e-07 28.9 0.3 1.8e-06 28.0 0.3 1.5 1 0 0 1 1 1 1 WSC domain Wzy_C_2 PF11846.8 ORY43296.1 - 0.035 14.0 0.0 0.072 13.0 0.0 1.5 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal EphA2_TM PF14575.6 ORY43296.1 - 0.084 13.8 0.0 0.16 12.8 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain WSC PF01822.19 ORY43299.1 - 4.6e-06 26.7 5.7 1.1e-05 25.6 5.7 1.7 1 0 0 1 1 1 1 WSC domain Phage_Coat_B PF05356.11 ORY43300.1 - 0.12 12.3 0.0 0.36 10.8 0.0 1.8 1 0 0 1 1 1 0 Phage Coat protein B PRIMA1 PF16101.5 ORY43301.1 - 0.023 14.7 0.2 0.078 13.0 0.0 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 WSC PF01822.19 ORY43301.1 - 0.12 12.6 4.6 1.5 9.1 4.6 2.3 1 1 0 1 1 1 0 WSC domain Cadherin_C_2 PF16492.5 ORY43303.1 - 0.023 15.4 0.1 0.048 14.4 0.1 1.5 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal DZR PF12773.7 ORY43304.1 - 0.17 11.9 7.9 3.1 7.9 0.4 3.1 2 1 0 2 2 2 0 Double zinc ribbon hSac2 PF12456.8 ORY43305.1 - 0.07 12.8 0.0 14 5.4 0.0 2.3 2 0 0 2 2 2 0 Inositol phosphatase Di19_C PF14571.6 ORY43305.1 - 0.088 13.3 0.9 0.26 11.9 0.9 1.7 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal DUF4276 PF14103.6 ORY43305.1 - 0.1 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4276) LRR_8 PF13855.6 ORY43306.1 - 1.4e-11 44.0 20.9 4.5e-07 29.5 12.7 2.5 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY43306.1 - 1.5e-11 44.3 22.5 3.8e-06 27.2 5.0 4.3 2 2 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORY43306.1 - 5e-07 29.4 2.9 0.00011 21.7 0.1 2.1 2 0 0 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 ORY43306.1 - 0.00033 20.5 15.6 0.86 9.8 0.1 6.3 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 ORY43306.1 - 0.054 14.1 18.8 6.8 7.7 1.4 5.9 5 1 0 5 5 5 0 Leucine Rich Repeat DUF1685 PF07939.11 ORY43307.1 - 0.067 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1685) Octopine_DH PF02317.17 ORY43307.1 - 0.11 12.6 0.0 0.48 10.5 0.0 1.9 2 0 0 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain DUF3984 PF13136.6 ORY43307.1 - 0.26 10.6 5.8 0.38 10.1 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) ANF_receptor PF01094.28 ORY43308.1 - 2.8e-30 105.6 0.5 6.9e-30 104.3 0.5 1.5 1 1 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY43308.1 - 0.0047 16.6 3.3 0.013 15.2 3.3 1.6 1 1 0 1 1 1 1 Periplasmic binding protein DUF3096 PF11295.8 ORY43309.1 - 0.011 15.4 0.2 0.019 14.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3096) RNase_HII PF01351.18 ORY43310.1 - 3e-41 141.5 0.0 3.7e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII HNHc_6 PF16784.5 ORY43310.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative HNHc nuclease NmrA PF05368.13 ORY43311.1 - 5.2e-15 55.6 0.2 1.1e-14 54.6 0.2 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY43311.1 - 4.7e-14 52.7 0.4 8.7e-14 51.8 0.4 1.5 1 1 0 1 1 1 1 NAD(P)H-binding PIRT PF15099.6 ORY43311.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family PBP_like_2 PF12849.7 ORY43312.1 - 4.3e-16 59.4 0.2 1.1e-15 58.1 0.2 1.5 1 1 0 1 1 1 1 PBP superfamily domain Phage_holin_5_2 PF16079.5 ORY43312.1 - 0.11 12.8 0.3 0.36 11.2 0.3 1.8 1 0 0 1 1 1 0 Phage holin family Hol44, in holin superfamily V SPX PF03105.19 ORY43315.1 - 2.1 8.2 5.2 2.6 7.9 5.2 1.2 1 0 0 1 1 1 0 SPX domain PBP_like_2 PF12849.7 ORY43316.1 - 6.4e-10 39.2 0.0 7.2e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 PBP superfamily domain Flavodoxin_1 PF00258.25 ORY43316.1 - 0.13 12.5 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin PBP_like PF12727.7 ORY43316.1 - 0.2 10.7 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 PBP superfamily domain EF-hand_6 PF13405.6 ORY43317.1 - 2.8e-14 51.7 5.0 8.6e-08 31.5 1.7 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 ORY43317.1 - 5.7e-12 44.3 8.3 2.1e-06 26.9 2.3 3.4 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 ORY43317.1 - 3.4e-10 40.2 8.5 9.3e-09 35.6 2.3 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 ORY43317.1 - 5.1e-07 28.9 2.8 0.0063 16.0 2.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 ORY43317.1 - 6.9e-07 29.0 4.9 0.0022 17.8 0.2 3.3 1 1 2 3 3 3 2 EF-hand domain pair UPF0154 PF03672.13 ORY43317.1 - 0.0023 17.9 0.2 0.2 11.7 0.0 2.8 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 ORY43317.1 - 0.0027 18.5 0.1 0.0066 17.3 0.1 1.6 1 1 1 2 2 2 1 EF-hand domain EF-hand_9 PF14658.6 ORY43317.1 - 0.013 15.8 0.1 0.9 9.9 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain Rad50_zn_hook PF04423.14 ORY43318.1 - 2.7e-07 30.3 4.6 9e-07 28.6 0.0 4.4 4 0 0 4 4 4 1 Rad50 zinc hook motif SbcCD_C PF13558.6 ORY43318.1 - 4.4e-05 23.6 0.0 0.00014 22.0 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 ORY43318.1 - 0.00047 19.7 1.8 0.001 18.5 1.8 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain Endonuc-BglII PF09195.11 ORY43318.1 - 0.017 14.9 1.8 0.072 12.9 1.0 2.5 2 0 0 2 2 2 0 Restriction endonuclease BglII DUF2045 PF09741.9 ORY43319.1 - 3.4e-39 134.6 0.1 8.3e-38 130.1 0.1 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2045) TRAP_beta PF05753.14 ORY43319.1 - 0.061 12.7 0.9 0.79 9.1 0.0 2.2 2 0 0 2 2 2 0 Translocon-associated protein beta (TRAPB) DUF1864 PF08933.11 ORY43319.1 - 0.17 10.6 0.1 0.27 10.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) ZapB PF06005.12 ORY43320.1 - 0.0083 16.5 0.2 0.021 15.3 0.2 1.6 1 0 0 1 1 1 1 Cell division protein ZapB Herpes_BLRF2 PF05812.12 ORY43320.1 - 0.024 14.8 0.4 0.063 13.4 0.4 1.7 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein PRKG1_interact PF15898.5 ORY43320.1 - 0.03 15.2 1.2 0.092 13.7 0.8 2.0 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Myc-LZ PF02344.15 ORY43320.1 - 0.25 11.4 1.8 0.74 10.0 1.8 1.8 1 0 0 1 1 1 0 Myc leucine zipper domain DivIC PF04977.15 ORY43320.1 - 0.49 10.2 1.6 1 9.2 1.6 1.4 1 0 0 1 1 1 0 Septum formation initiator Ank_2 PF12796.7 ORY43321.1 - 1e-13 51.6 3.5 2.9e-07 31.0 0.0 3.6 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY43321.1 - 1.1e-09 37.6 7.2 0.41 11.4 0.0 7.2 6 1 1 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 ORY43321.1 - 4.8e-07 29.9 6.0 0.059 13.7 0.8 4.9 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY43321.1 - 8.9e-05 22.8 4.4 0.23 12.0 0.4 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 ORY43321.1 - 0.00012 22.6 2.1 3 8.5 0.2 4.3 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ribosomal_L35p PF01632.19 ORY43322.1 - 8.5e-07 29.4 7.4 3.4e-06 27.4 7.4 2.1 1 1 0 1 1 1 1 Ribosomal protein L35 MCD PF05292.11 ORY43324.1 - 1.6e-93 313.0 0.0 3.1e-93 312.1 0.0 1.4 2 0 0 2 2 2 1 Malonyl-CoA decarboxylase C-terminal domain MCD_N PF17408.2 ORY43324.1 - 2.2e-13 50.2 0.8 5.5e-13 48.8 0.5 1.9 2 0 0 2 2 2 1 Malonyl-CoA decarboxylase N-terminal domain C2 PF00168.30 ORY43326.1 - 3.9e-08 33.5 0.0 1.4e-07 31.8 0.0 2.0 1 0 0 1 1 1 1 C2 domain PH PF00169.29 ORY43326.1 - 4.5e-05 23.9 0.4 0.0033 17.9 0.4 3.1 1 1 0 1 1 1 1 PH domain FCH PF00611.23 ORY43326.1 - 0.026 14.8 0.2 0.026 14.8 0.2 2.5 2 1 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain Toxin_28 PF08115.11 ORY43326.1 - 0.23 11.4 5.6 10 6.1 0.1 2.4 2 0 0 2 2 2 0 SFI toxin family EMC3_TMCO1 PF01956.16 ORY43326.1 - 0.66 9.7 2.2 1.3 8.7 2.2 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like PdaC PF13739.6 ORY43326.1 - 6.1 7.9 8.0 35 5.5 3.4 2.8 3 0 0 3 3 3 0 Deacetylase PdaC DUF3512 PF12024.8 ORY43327.1 - 0.00049 19.7 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3512) ZZ PF00569.17 ORY43328.1 - 8.3e-05 22.3 7.4 0.00017 21.4 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 ORY43328.1 - 0.52 10.7 6.9 0.92 9.9 6.9 1.3 1 0 0 1 1 1 0 C1 domain Mucin-like PF16058.5 ORY43328.1 - 1 9.5 13.1 3 8.0 13.1 1.7 1 0 0 1 1 1 0 Mucin-like Pyridoxal_deC PF00282.19 ORY43329.1 - 2.8e-59 200.7 0.0 7.2e-59 199.4 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF5494 PF17598.2 ORY43330.1 - 0.12 12.5 0.2 0.27 11.4 0.1 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5494) HAUS6_N PF14661.6 ORY43331.1 - 0.0059 16.2 0.5 0.55 9.8 0.0 2.2 2 0 0 2 2 2 2 HAUS augmin-like complex subunit 6 N-terminus DHR10 PF18595.1 ORY43331.1 - 1.8 8.6 9.6 1.1 9.4 4.4 2.2 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Amidase PF01425.21 ORY43332.1 - 7.6e-107 358.1 1.2 9.8e-107 357.7 1.2 1.0 1 0 0 1 1 1 1 Amidase DUF724 PF05266.14 ORY43333.1 - 0.0036 17.2 10.3 0.0036 17.2 10.3 4.2 3 1 1 4 4 4 1 Protein of unknown function (DUF724) ADIP PF11559.8 ORY43333.1 - 0.25 11.4 30.7 0.65 10.1 0.5 4.7 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding Fez1 PF06818.15 ORY43333.1 - 0.33 11.4 36.1 1.1 9.7 0.2 4.1 2 1 1 3 3 3 0 Fez1 LPP PF04728.13 ORY43333.1 - 1.5 9.3 15.0 2.7 8.4 0.5 5.1 4 1 1 5 5 5 0 Lipoprotein leucine-zipper PKcGMP_CC PF16808.5 ORY43333.1 - 2.2 8.2 8.2 12 5.9 0.3 4.1 3 1 1 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FUSC PF04632.12 ORY43333.1 - 4.5 5.7 8.7 7.3 5.0 8.7 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family HAD_2 PF13419.6 ORY43334.1 - 8.6e-09 35.7 0.0 2.1e-08 34.5 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY43334.1 - 2.4e-07 31.2 0.0 3.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY43334.1 - 0.0044 17.0 0.0 0.0088 16.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.7 ORY43334.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.8 1 1 0 1 1 1 0 Acid Phosphatase Methyltransf_8 PF05148.15 ORY43335.1 - 4.6e-81 271.8 0.0 6e-81 271.5 0.0 1.1 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 ORY43335.1 - 7.7e-07 29.7 0.1 3.8e-06 27.5 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY43335.1 - 1.5e-05 25.6 0.0 0.0015 19.2 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY43335.1 - 0.00032 20.5 0.0 0.12 12.1 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 ORY43335.1 - 0.00086 19.3 1.0 0.01 15.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY43335.1 - 0.029 13.7 0.0 0.55 9.5 0.0 2.7 2 1 2 4 4 4 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 ORY43335.1 - 0.075 12.6 0.0 6.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase small domain Glyco_transf_34 PF05637.12 ORY43336.1 - 1.8e-16 60.6 2.8 5e-08 33.0 0.4 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family Y_phosphatase2 PF03162.13 ORY43337.1 - 1.5e-48 164.5 0.0 1.7e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 ORY43337.1 - 0.00078 19.5 0.0 0.0018 18.3 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 ORY43337.1 - 0.037 13.8 0.0 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain TPT PF03151.16 ORY43338.1 - 1.6e-07 31.0 20.1 1.3e-05 24.7 3.3 3.0 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 ORY43338.1 - 0.00025 21.2 28.2 0.038 14.2 9.1 3.2 3 0 0 3 3 3 3 EamA-like transporter family TPT PF03151.16 ORY43339.1 - 3.6e-08 33.1 30.0 0.0002 20.8 12.1 3.0 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 ORY43340.1 - 0.0086 16.3 38.4 0.018 15.2 8.8 3.4 3 1 0 3 3 3 3 EamA-like transporter family DUF4201 PF13870.6 ORY43341.1 - 2e-46 157.9 20.0 2e-46 157.9 20.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4201) FAD_binding_3 PF01494.19 ORY43343.1 - 9.9e-29 100.7 0.0 5.3e-28 98.3 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 ORY43343.1 - 2.7e-05 24.3 0.4 5.7e-05 23.3 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY43343.1 - 2.9e-05 23.8 0.2 0.0001 22.0 0.5 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY43343.1 - 0.00013 21.3 0.1 0.0038 16.5 0.2 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY43343.1 - 0.00036 21.0 0.5 0.33 11.5 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY43343.1 - 0.005 16.0 0.6 0.0083 15.2 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 ORY43343.1 - 0.015 14.6 0.4 0.029 13.6 0.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 ORY43343.1 - 0.12 13.0 0.9 0.31 11.7 0.9 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Trp_halogenase PF04820.14 ORY43343.1 - 0.15 10.9 0.3 0.84 8.4 0.2 2.0 2 0 0 2 2 2 0 Tryptophan halogenase SNF2_N PF00176.23 ORY43344.1 - 7.4e-67 225.5 0.1 1.8e-66 224.3 0.1 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 ORY43344.1 - 1.2e-27 95.6 0.4 1.6e-16 60.0 0.1 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 ORY43344.1 - 1.4e-19 70.4 0.0 2.8e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.6 ORY43344.1 - 1.5e-13 51.0 1.7 4.2e-13 49.6 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) ResIII PF04851.15 ORY43344.1 - 1.7e-09 37.9 0.0 5.4e-09 36.3 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 ORY43344.1 - 1.8e-08 33.9 0.2 5e-08 32.5 0.2 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Cdh1_DBD_1 PF18196.1 ORY43344.1 - 3e-08 34.0 0.1 2.8e-07 30.9 0.1 2.8 1 0 0 1 1 1 1 Chromodomain helicase DNA-binding domain 1 CDH1_2_SANT_HL1 PF18375.1 ORY43344.1 - 7.1e-07 29.8 2.0 1.8e-06 28.5 0.1 2.9 2 0 0 2 2 1 1 CDH1/2 SANT-Helical linker 1 ERCC3_RAD25_C PF16203.5 ORY43344.1 - 1.7e-05 24.2 0.3 3.5e-05 23.1 0.3 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SLIDE PF09111.10 ORY43344.1 - 0.02 14.9 0.0 0.15 12.1 0.0 2.5 2 0 0 2 2 2 0 SLIDE Tudor-knot PF11717.8 ORY43344.1 - 0.059 13.3 0.0 2 8.4 0.0 2.6 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain CytochromB561_N PF09786.9 ORY43344.1 - 1.2 8.1 5.3 0.28 10.1 1.2 2.0 2 0 0 2 2 2 0 Cytochrome B561, N terminal WD40 PF00400.32 ORY43345.1 - 0.00016 22.4 0.1 0.052 14.4 0.0 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat SNAP PF14938.6 ORY43347.1 - 3.7e-102 341.6 9.3 4.2e-102 341.4 9.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_8 PF13181.6 ORY43347.1 - 0.016 15.4 10.5 1 9.7 0.2 5.2 3 1 3 6 6 6 0 Tetratricopeptide repeat Spatacsin_C PF14649.6 ORY43347.1 - 0.045 12.9 4.6 0.48 9.5 4.6 2.2 1 1 0 1 1 1 0 Spatacsin C-terminus TPR_MalT PF17874.1 ORY43347.1 - 0.048 13.0 4.4 0.5 9.7 4.6 2.2 1 1 1 2 2 2 0 MalT-like TPR region TPR_6 PF13174.6 ORY43347.1 - 0.06 14.0 10.5 4.1 8.2 0.2 5.6 5 2 1 6 6 6 0 Tetratricopeptide repeat MAS20 PF02064.15 ORY43347.1 - 0.068 13.3 0.5 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 MAS20 protein import receptor TPR_14 PF13428.6 ORY43347.1 - 0.086 13.7 9.9 6.9 7.8 0.0 5.7 5 1 0 5 5 5 0 Tetratricopeptide repeat MARCKS PF02063.17 ORY43347.1 - 0.25 11.3 5.8 0.34 10.9 5.8 1.1 1 0 0 1 1 1 0 MARCKS family TPR_2 PF07719.17 ORY43347.1 - 0.39 11.0 16.2 0.69 10.2 0.0 6.5 5 2 3 8 8 8 0 Tetratricopeptide repeat Pkinase PF00069.25 ORY43348.1 - 8.6e-50 169.5 0.1 1.4e-49 168.8 0.1 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY43348.1 - 2.5e-20 72.8 0.0 4.3e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 ORY43348.1 - 0.0019 17.9 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 ORY43348.1 - 0.014 14.7 0.0 0.038 13.3 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY43348.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY43348.1 - 0.028 13.2 0.0 0.055 12.2 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase zf-H2C2_2 PF13465.6 ORY43348.1 - 0.066 13.7 0.7 0.17 12.4 0.7 1.7 1 0 0 1 1 1 0 Zinc-finger double domain Myosin_head PF00063.21 ORY43349.1 - 6.5e-236 784.7 1.3 6.5e-236 784.7 1.3 1.8 2 0 0 2 2 2 1 Myosin head (motor domain) MyTH4 PF00784.17 ORY43349.1 - 6.2e-44 148.9 0.0 1.3e-21 77.1 0.2 3.2 2 0 0 2 2 2 2 MyTH4 domain FERM_M PF00373.18 ORY43349.1 - 4e-24 85.3 0.1 6.9e-15 55.5 0.0 3.5 3 0 0 3 3 3 2 FERM central domain IQ PF00612.27 ORY43349.1 - 2e-11 42.7 10.7 0.00047 19.7 0.4 3.8 3 0 0 3 3 3 3 IQ calmodulin-binding motif RA PF00788.23 ORY43349.1 - 3.1e-08 34.1 0.0 0.00011 22.8 0.0 3.4 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain Ras_bdg_2 PF14847.6 ORY43349.1 - 0.0024 18.2 0.0 0.0081 16.5 0.0 1.9 1 0 0 1 1 1 1 Ras-binding domain of Byr2 AAA_22 PF13401.6 ORY43349.1 - 0.016 15.5 0.6 0.13 12.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain TUG-UBL1 PF11470.8 ORY43349.1 - 0.078 13.2 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 TUG ubiquitin-like domain AAA_16 PF13191.6 ORY43349.1 - 0.24 11.7 0.0 0.24 11.7 0.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain GAS PF13851.6 ORY43350.1 - 0.0017 17.7 24.4 0.0035 16.7 11.8 2.3 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding HOOK PF05622.12 ORY43350.1 - 0.02 13.1 20.6 0.02 13.1 4.9 2.4 2 1 0 2 2 2 0 HOOK protein DUF724 PF05266.14 ORY43350.1 - 0.17 11.7 24.6 0.03 14.1 4.5 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF724) APG6_N PF17675.1 ORY43350.1 - 0.58 10.7 27.6 1.2 9.7 12.8 2.9 2 1 0 2 2 2 0 Apg6 coiled-coil region UPF0242 PF06785.11 ORY43350.1 - 2.1 8.4 21.2 1.3 9.1 10.3 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF445 PF04286.12 ORY43350.1 - 3.1 7.5 14.1 2 8.2 10.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF445) KELK PF15796.5 ORY43350.1 - 9 6.8 22.4 0.22 12.0 3.1 3.5 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PHTB1_N PF14727.6 ORY43351.1 - 9.9e-34 117.4 0.4 1.4e-33 116.9 0.4 1.2 1 0 0 1 1 1 1 PTHB1 N-terminus RabGAP-TBC PF00566.18 ORY43353.1 - 1.3e-13 51.1 1.2 8.8e-13 48.4 0.4 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Sld3_N PF18523.1 ORY43353.1 - 0.094 12.8 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Sld3 N-terminal domain Lebercilin PF15619.6 ORY43354.1 - 2.8e-18 66.3 24.1 5.5e-18 65.3 24.1 1.5 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease HMMR_N PF15905.5 ORY43354.1 - 0.0088 15.6 17.5 0.0088 15.6 17.5 2.5 2 1 1 3 3 3 1 Hyaluronan mediated motility receptor N-terminal SpoIIID PF12116.8 ORY43354.1 - 0.7 10.0 5.4 3.4 7.8 0.2 3.2 4 0 0 4 4 4 0 Stage III sporulation protein D FAM76 PF16046.5 ORY43354.1 - 2 7.7 25.8 1.3 8.3 21.0 2.3 1 1 1 2 2 2 0 FAM76 protein UPF0242 PF06785.11 ORY43354.1 - 2.6 8.1 22.0 4.4 7.4 10.7 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Aminotran_3 PF00202.21 ORY43354.1 - 3.4 6.2 5.6 7.8 5.0 0.3 2.2 1 1 1 2 2 2 0 Aminotransferase class-III Rpn9_C PF18261.1 ORY43354.1 - 5.6 6.6 6.8 5.3 6.7 2.0 3.0 2 1 1 3 3 3 0 Rpn9 C-terminal helix BMFP PF04380.13 ORY43354.1 - 6.5 7.3 9.5 0.23 12.0 0.8 2.9 3 0 0 3 3 3 0 Membrane fusogenic activity Homeodomain PF00046.29 ORY43355.1 - 2.4e-08 33.7 1.0 6.6e-08 32.3 1.0 1.7 1 0 0 1 1 1 1 Homeodomain Homeodomain PF00046.29 ORY43357.1 - 3.8e-10 39.4 5.4 6.9e-10 38.6 5.4 1.4 1 0 0 1 1 1 1 Homeodomain zf-DBF PF07535.12 ORY43358.1 - 8.6e-15 54.6 1.0 1.9e-14 53.5 1.0 1.5 1 0 0 1 1 1 1 DBF zinc finger Dfp1_Him1_M PF08630.10 ORY43358.1 - 1e-12 48.4 0.5 3.9e-12 46.5 0.0 2.3 2 0 0 2 2 2 1 Dfp1/Him1, central region SDA1 PF05285.12 ORY43358.1 - 0.099 12.1 34.8 0.097 12.1 8.9 2.3 2 0 0 2 2 2 0 SDA1 TFIIF_alpha PF05793.12 ORY43358.1 - 9.2 4.7 43.4 4.3 5.8 23.9 2.7 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Biopterin_H PF00351.21 ORY43359.1 - 6.5e-150 498.8 0.2 9e-150 498.3 0.2 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 ORY43359.1 - 9.6e-05 22.1 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 ORY43359.1 - 0.00053 20.5 0.0 0.0009 19.8 0.0 1.3 1 0 0 1 1 1 1 ACT domain NPL PF17800.1 ORY43360.1 - 1.7e-13 51.0 0.0 2.4e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Nucleoplasmin-like domain DUF945 PF06097.11 ORY43360.1 - 0.2 10.7 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) Ras PF00071.22 ORY43361.1 - 6e-60 201.5 0.6 7.6e-60 201.2 0.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY43361.1 - 5.4e-38 129.9 0.2 7.6e-38 129.4 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY43361.1 - 1.1e-16 60.8 0.2 1.3e-16 60.5 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY43361.1 - 5.2e-07 29.4 0.2 2.8e-06 27.0 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 ORY43361.1 - 2e-06 27.4 0.1 3.8e-06 26.5 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORY43361.1 - 6.4e-06 25.7 0.2 7.8e-06 25.4 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY43361.1 - 8.1e-06 25.9 0.1 1.5e-05 25.0 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY43361.1 - 0.00044 20.2 0.1 0.42 10.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 ORY43361.1 - 0.0028 17.5 0.1 0.0075 16.1 0.0 1.6 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 ORY43361.1 - 0.021 14.3 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FlgH PF02107.16 ORY43361.1 - 0.022 14.3 0.2 0.033 13.8 0.2 1.3 1 0 0 1 1 1 0 Flagellar L-ring protein TIR_2 PF13676.6 ORY43361.1 - 0.048 14.3 0.1 0.077 13.6 0.1 1.3 1 0 0 1 1 1 0 TIR domain TniB PF05621.11 ORY43361.1 - 0.051 13.0 0.0 0.73 9.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein ATPase_2 PF01637.18 ORY43361.1 - 0.064 13.2 0.1 0.12 12.3 0.1 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea TetR_C_16 PF17920.1 ORY43361.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.5 2 0 0 2 2 1 0 Tetracyclin repressor-like, C-terminal domain Ras PF00071.22 ORY43362.1 - 6.3e-60 201.4 0.3 8e-60 201.1 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY43362.1 - 3.4e-37 127.3 0.1 4.9e-37 126.8 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY43362.1 - 8.4e-16 57.9 0.1 9.4e-16 57.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY43362.1 - 2.3e-06 27.3 0.1 1.6e-05 24.6 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 ORY43362.1 - 1.7e-05 24.4 0.1 2.3e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 ORY43362.1 - 3e-05 24.1 0.0 4.8e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY43362.1 - 6.5e-05 22.9 0.0 0.091 12.7 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 ORY43362.1 - 8.1e-05 22.1 0.1 0.0001 21.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FlgH PF02107.16 ORY43362.1 - 0.0041 16.7 0.3 0.0061 16.2 0.3 1.2 1 0 0 1 1 1 1 Flagellar L-ring protein AAA_7 PF12775.7 ORY43362.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 ORY43362.1 - 0.15 11.4 0.0 1.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein Methyltr_RsmB-F PF01189.17 ORY43363.1 - 6.2e-33 114.1 0.0 2.1e-32 112.4 0.0 1.9 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 ORY43363.1 - 0.01 15.9 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase W2 PF02020.18 ORY43364.1 - 4.2e-18 65.3 1.1 1.3e-17 63.6 1.1 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon RL PF17797.1 ORY43364.1 - 0.076 13.0 0.3 6 6.9 0.1 2.5 2 0 0 2 2 2 0 RL domain Chordopox_A33R PF05966.12 ORY43365.1 - 0.079 12.2 0.1 0.29 10.4 0.0 1.7 2 0 0 2 2 2 0 Chordopoxvirus A33R protein DUF3318 PF11780.8 ORY43367.1 - 0.077 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Amnionless PF14828.6 ORY43367.1 - 0.095 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF3439 PF11921.8 ORY43367.1 - 0.76 9.8 20.5 0.11 12.4 11.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 ORY43367.1 - 1.6 6.6 7.0 1.9 6.4 7.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TMEM154 PF15102.6 ORY43367.1 - 4.2 7.3 6.7 14 5.6 5.3 2.1 2 0 0 2 2 2 0 TMEM154 protein family DUF3995 PF13160.6 ORY43369.1 - 0.032 14.6 0.1 0.073 13.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) stn_TNFRSF12A PF12191.8 ORY43369.1 - 0.041 14.1 0.6 0.076 13.2 0.4 1.6 1 1 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF3827 PF12877.7 ORY43369.1 - 0.17 10.2 0.4 0.24 9.7 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) WSC PF01822.19 ORY43369.1 - 0.25 11.6 3.6 0.78 10.0 3.6 1.8 1 1 0 1 1 1 0 WSC domain Arf PF00025.21 ORY43372.1 - 1e-49 168.3 0.0 1.2e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 ORY43372.1 - 1.1e-11 44.5 2.3 4.6e-07 29.3 0.6 2.8 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 ORY43372.1 - 8.9e-11 42.1 0.0 1.2e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORY43372.1 - 1.6e-09 37.5 0.0 2e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 ORY43372.1 - 1.7e-09 37.4 0.0 2.1e-09 37.1 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORY43372.1 - 1.9e-09 37.2 0.0 2.5e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY43372.1 - 1.9e-08 34.4 0.0 3.1e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY43372.1 - 0.00022 20.8 0.1 0.0082 15.7 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 ORY43372.1 - 0.0026 17.5 0.1 0.006 16.3 0.1 1.6 1 1 0 1 1 1 1 P-loop containing region of AAA domain AAA_7 PF12775.7 ORY43372.1 - 0.015 14.8 0.1 0.024 14.2 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 ORY43372.1 - 0.046 13.2 0.8 0.11 12.0 0.8 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.23 ORY43372.1 - 0.11 12.6 0.3 1.7 8.7 0.1 2.0 1 1 1 2 2 2 0 Dynamin family TniB PF05621.11 ORY43372.1 - 0.17 11.3 0.0 0.63 9.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein 6PF2K PF01591.18 ORY43372.1 - 0.18 11.1 0.0 0.31 10.3 0.0 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase Septin PF00735.18 ORY43372.1 - 0.19 11.0 0.1 0.26 10.5 0.1 1.4 1 1 0 1 1 1 0 Septin SAP18 PF06487.12 ORY43373.1 - 6.9e-22 78.1 0.0 6.9e-22 78.1 0.0 2.3 2 1 0 2 2 2 1 Sin3 associated polypeptide p18 (SAP18) MCM_bind PF09739.9 ORY43373.1 - 0.3 9.5 9.2 0.41 9.0 9.2 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor CDC45 PF02724.14 ORY43373.1 - 0.8 7.9 10.8 1.1 7.4 10.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 ORY43373.1 - 3.1 5.9 15.5 4.4 5.4 15.5 1.1 1 0 0 1 1 1 0 Nop14-like family Ndc1_Nup PF09531.10 ORY43373.1 - 6.1 5.4 8.1 7.9 5.0 8.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 ORY43373.1 - 7.4 5.2 12.4 11 4.7 12.4 1.2 1 0 0 1 1 1 0 Presenilin Glyoxalase PF00903.25 ORY43374.1 - 0.0011 19.1 0.0 0.0017 18.5 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily LysR_substrate PF03466.20 ORY43374.1 - 0.19 11.1 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 LysR substrate binding domain Tubulin PF00091.25 ORY43375.1 - 1.9e-71 240.4 0.0 2.7e-71 239.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORY43375.1 - 4.3e-43 146.5 0.1 7e-43 145.8 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 ORY43375.1 - 3.7e-05 24.0 0.1 0.00019 21.7 0.0 2.0 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 ORY43375.1 - 0.0002 21.1 0.0 0.00037 20.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain DUF3403 PF11883.8 ORY43375.1 - 0.042 13.9 0.0 0.24 11.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3403) Tubulin_2 PF13809.6 ORY43375.1 - 0.098 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Tubulin like ACCA PF03255.14 ORY43376.1 - 0.0028 17.5 7.0 0.068 13.0 0.8 2.4 2 0 0 2 2 2 2 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit SPT16 PF08644.11 ORY43376.1 - 0.05 13.8 5.5 0.13 12.5 0.6 2.2 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) GrpE PF01025.19 ORY43376.1 - 0.086 12.5 13.9 0.4 10.3 5.8 2.3 2 1 0 2 2 2 0 GrpE NPV_P10 PF05531.12 ORY43376.1 - 0.19 12.2 3.0 0.36 11.3 1.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 ORY43376.1 - 0.19 10.6 17.0 0.8 8.5 4.4 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein OmpH PF03938.14 ORY43376.1 - 0.33 11.3 8.9 0.42 10.9 0.6 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF2203 PF09969.9 ORY43376.1 - 0.5 11.1 4.6 8.3 7.2 0.4 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Occludin_ELL PF07303.13 ORY43376.1 - 0.6 10.9 8.7 0.16 12.7 0.9 2.6 2 2 0 2 2 2 0 Occludin homology domain Retrotrans_gag PF03732.17 ORY43376.1 - 0.71 10.2 4.3 9.3 6.6 0.3 2.6 2 0 0 2 2 2 0 Retrotransposon gag protein CENP-H PF05837.12 ORY43376.1 - 0.78 10.2 11.9 0.69 10.3 3.3 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) FliD_C PF07195.12 ORY43376.1 - 0.86 9.0 8.3 2.7 7.4 0.4 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus Cauli_AT PF03233.13 ORY43376.1 - 2.7 7.9 9.8 0.09 12.7 1.6 2.2 2 1 1 3 3 3 0 Aphid transmission protein DUF4140 PF13600.6 ORY43376.1 - 3.5 8.1 9.3 5.9 7.4 3.6 2.6 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Homeodomain PF00046.29 ORY43376.1 - 4 7.3 7.0 0.9 9.4 1.9 2.5 2 1 0 2 2 2 0 Homeodomain AAA_23 PF13476.6 ORY43376.1 - 4.9 7.6 14.6 2.5 8.5 5.4 2.1 2 0 0 2 2 2 0 AAA domain TMPIT PF07851.13 ORY43376.1 - 6.3 5.9 7.9 7.4 5.7 0.6 2.1 2 0 0 2 2 2 0 TMPIT-like protein FAM184 PF15665.5 ORY43376.1 - 8.6 6.1 17.3 2.5 7.8 4.6 2.2 1 1 0 2 2 2 0 Family with sequence similarity 184, A and B Kinesin PF00225.23 ORY43377.1 - 2.3e-102 342.4 0.4 4.7e-102 341.3 0.4 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY43377.1 - 7e-24 84.5 0.2 2.6e-23 82.6 0.2 2.0 1 0 0 1 1 1 1 Microtubule binding CENP-F_leu_zip PF10473.9 ORY43377.1 - 0.2 11.7 16.5 0.43 10.6 2.9 3.4 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 ORY43377.1 - 0.22 11.6 9.9 1.8 8.6 0.5 3.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus APG6_N PF17675.1 ORY43377.1 - 0.31 11.6 15.7 1.2 9.7 1.0 3.0 2 1 0 2 2 2 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 ORY43377.1 - 0.98 9.7 9.5 3 8.1 1.2 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.8 ORY43377.1 - 1.1 9.3 18.5 0.025 14.7 4.0 3.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding KIAA1430 PF13879.6 ORY43377.1 - 1.2 9.9 11.0 3.2 8.6 0.3 3.6 3 0 0 3 3 3 0 KIAA1430 homologue Spc24 PF08286.11 ORY43377.1 - 2.3 8.5 10.9 4.7 7.5 1.8 3.5 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 eIF3_N PF09440.10 ORY43377.1 - 3 8.3 7.6 5.3 7.5 0.8 2.6 2 1 0 2 2 2 0 eIF3 subunit 6 N terminal domain GAS PF13851.6 ORY43377.1 - 6.8 6.0 19.6 1.5 8.1 1.4 2.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF3336 PF11815.8 ORY43378.1 - 8.3e-31 106.6 4.9 1.2e-30 106.0 4.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 ORY43378.1 - 1.2e-15 58.3 0.0 2.1e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Fer4_12 PF13353.6 ORY43378.1 - 0.14 12.5 0.0 0.41 10.9 0.0 1.8 1 1 1 2 2 2 0 4Fe-4S single cluster domain SWIRM PF04433.17 ORY43379.1 - 2.2e-18 66.4 0.0 5.8e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain JAB PF01398.21 ORY43379.1 - 2.5e-11 43.6 0.1 7e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 ORY43379.1 - 2e-08 34.0 0.1 6.5e-08 32.4 0.1 1.9 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain UIM PF02809.20 ORY43379.1 - 0.009 15.9 0.4 0.009 15.9 0.4 2.2 3 0 0 3 3 3 1 Ubiquitin interaction motif Glyco_hydro_2 PF00703.21 ORY43380.1 - 0.00015 22.4 0.0 0.00039 21.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 DUF2715 PF10895.8 ORY43380.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2715) Cytotoxic PF09000.10 ORY43380.1 - 0.16 12.4 0.1 0.32 11.3 0.1 1.4 1 0 0 1 1 1 0 Cytotoxic DUF4203 PF13886.6 ORY43381.1 - 1.2e-09 38.1 17.4 1.8e-09 37.6 17.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) RasGEF PF00617.19 ORY43383.1 - 1.1e-28 100.6 0.3 2.8e-28 99.3 0.3 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY43383.1 - 2.3e-06 27.8 5.2 5.5e-06 26.6 0.3 3.7 3 1 0 3 3 3 1 RasGEF N-terminal motif TSC22 PF01166.18 ORY43383.1 - 0.13 12.6 0.2 0.61 10.4 0.2 2.2 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF4429 PF14472.6 ORY43383.1 - 0.14 12.7 0.1 0.32 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4429) DUF3439 PF11921.8 ORY43383.1 - 0.91 9.5 7.8 4.2 7.4 3.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) RasGEF PF00617.19 ORY43384.1 - 5.4e-13 49.5 0.1 7.3e-13 49.1 0.1 1.2 1 0 0 1 1 1 1 RasGEF domain Mito_carr PF00153.27 ORY43385.1 - 8.4e-55 182.7 6.3 1.6e-20 72.8 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein GDC-P PF02347.16 ORY43386.1 - 6e-188 625.0 0.3 3.6e-180 599.4 0.0 2.3 2 0 0 2 2 2 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 ORY43386.1 - 1.5e-06 27.4 0.3 2.2e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ORY43386.1 - 0.00022 20.6 0.1 0.00049 19.5 0.1 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Ribosomal_L32p PF01783.23 ORY43387.1 - 2e-11 44.0 5.5 2.2e-11 43.8 5.5 1.0 1 0 0 1 1 1 1 Ribosomal L32p protein family Prok-RING_1 PF14446.6 ORY43387.1 - 0.027 14.4 0.1 0.038 13.9 0.1 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Tim44 PF04280.15 ORY43388.1 - 7.9e-07 29.3 0.0 1.5e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Tim44-like domain MBA1 PF07961.11 ORY43388.1 - 0.053 12.6 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 MBA1-like protein WD40 PF00400.32 ORY43389.1 - 4.7e-62 204.5 23.5 1.3e-07 32.2 1.6 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY43389.1 - 1.8e-20 73.0 1.1 0.00038 20.7 0.0 6.7 1 1 7 8 8 8 7 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY43389.1 - 1.5e-08 34.3 2.4 0.00055 19.4 0.4 3.8 2 1 1 3 3 3 2 WD40-like domain Nup160 PF11715.8 ORY43389.1 - 5.1e-07 28.7 3.6 0.25 9.9 0.3 4.5 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Frtz PF11768.8 ORY43389.1 - 0.0001 20.8 0.2 0.25 9.6 0.0 4.0 3 1 1 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz Nucleoporin_N PF08801.11 ORY43389.1 - 0.00044 19.1 0.2 0.084 11.6 0.0 2.6 1 1 1 2 2 2 2 Nup133 N terminal like WD40_3 PF15911.5 ORY43389.1 - 0.039 13.9 1.5 1.4 9.0 0.0 3.5 3 1 1 4 4 4 0 WD domain, G-beta repeat CEP19 PF14933.6 ORY43389.1 - 0.19 12.1 0.0 0.28 11.5 0.0 1.2 1 0 0 1 1 1 0 CEP19-like protein MMtag PF10159.9 ORY43390.1 - 3.3e-30 104.2 2.2 3.3e-30 104.2 2.2 1.5 2 0 0 2 2 2 1 Multiple myeloma tumor-associated Iwr1 PF08574.10 ORY43391.1 - 4.3e-13 50.1 18.7 4.3e-13 50.1 18.7 1.5 1 1 0 1 1 1 1 Transcription factor Iwr1 Tape_meas_lam_C PF09718.10 ORY43393.1 - 0.11 12.6 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Peptidase_S8 PF00082.22 ORY43394.1 - 2.5e-53 181.3 0.1 7.6e-53 179.7 0.1 1.8 1 1 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 ORY43394.1 - 5.3e-12 46.4 1.8 1.2e-11 45.3 1.8 1.7 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 ORY43394.1 - 2.1e-05 24.4 0.4 7e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 PA domain DUF2989 PF11207.8 ORY43396.1 - 0.014 15.2 0.6 0.014 15.2 0.6 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2989) DUF2845 PF11006.8 ORY43396.1 - 0.044 13.9 0.9 0.083 13.0 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2845) NusG_II PF07009.11 ORY43396.1 - 0.054 13.7 2.8 0.083 13.1 2.8 1.4 1 0 0 1 1 1 0 NusG domain II Ribosomal_60s PF00428.19 ORY43396.1 - 1.5 9.5 19.6 2.3 8.9 19.6 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF5633 PF18656.1 ORY43397.1 - 0.31 10.9 0.3 0.31 10.9 0.3 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5633) Chitin_synth_1 PF01644.17 ORY43398.1 - 1.3e-62 210.6 0.0 1.9e-62 210.0 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 ORY43398.1 - 3.5e-24 85.3 7.4 3.1e-20 72.3 0.2 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 ORY43398.1 - 3.9e-19 68.4 0.1 1.4e-18 66.6 0.1 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 ORY43398.1 - 1.3e-11 44.8 0.5 1.3e-11 44.8 0.5 2.5 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY43398.1 - 0.00024 21.1 0.0 0.00052 20.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DPM3 PF08285.11 ORY43398.1 - 0.049 13.8 1.5 0.11 12.8 0.1 2.3 1 1 1 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) LRR_8 PF13855.6 ORY43401.1 - 2.2e-13 49.8 11.3 5.3e-08 32.5 1.8 3.7 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 ORY43401.1 - 3.2e-12 46.4 19.3 1.6e-06 28.4 1.7 4.2 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORY43401.1 - 0.00078 19.0 2.5 0.34 10.4 0.0 2.2 1 1 1 2 2 2 2 Leucine-rich repeat LRR_5 PF13306.6 ORY43401.1 - 0.044 13.7 1.4 0.084 12.8 0.5 1.9 2 0 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) Herp-Cyclin PF09241.10 ORY43401.1 - 0.071 13.8 0.1 0.15 12.8 0.1 1.5 1 0 0 1 1 1 0 Herpesviridae viral cyclin LRR_1 PF00560.33 ORY43401.1 - 0.22 12.2 18.7 18 6.4 1.2 6.8 5 2 0 5 5 5 0 Leucine Rich Repeat DUF2408 PF10303.9 ORY43402.1 - 2.7e-11 44.1 1.6 2.6e-06 28.0 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF2408) LemA PF04011.12 ORY43402.1 - 0.014 15.2 0.1 0.29 11.0 0.1 2.1 2 0 0 2 2 2 0 LemA family APG17 PF04108.12 ORY43402.1 - 0.018 14.2 0.0 0.037 13.1 0.0 1.5 1 1 1 2 2 2 0 Autophagy protein Apg17 HBM PF16591.5 ORY43402.1 - 0.021 14.2 1.6 0.065 12.7 0.2 2.0 2 0 0 2 2 2 0 Helical bimodular sensor domain DHC_N2 PF08393.13 ORY43402.1 - 0.033 13.3 0.2 0.62 9.1 0.0 2.0 1 1 0 2 2 2 0 Dynein heavy chain, N-terminal region 2 End3 PF12761.7 ORY43402.1 - 0.059 13.5 0.3 6.4 6.9 0.1 2.3 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 Pox_I1 PF03289.13 ORY43402.1 - 0.079 12.1 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus protein I1 Cep57_CLD_2 PF14197.6 ORY43402.1 - 0.47 10.6 2.6 8.9 6.5 0.0 2.7 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 AidB_N PF18158.1 ORY43403.1 - 3.4e-26 92.0 0.0 5.9e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 ORY43403.1 - 1.9e-22 80.1 0.4 3.8e-22 79.1 0.2 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY43403.1 - 1.9e-10 40.8 0.0 5.5e-10 39.3 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY43403.1 - 0.087 13.1 0.0 0.2 11.9 0.0 1.7 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain ubiquitin PF00240.23 ORY43404.1 - 6.8e-07 29.0 1.0 2.5e-06 27.1 1.0 1.8 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 ORY43404.1 - 0.00011 22.6 0.4 0.00057 20.3 0.4 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 ORY43404.1 - 0.0088 15.9 0.9 0.043 13.7 0.9 1.8 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RAWUL PF16207.5 ORY43404.1 - 0.026 15.2 0.0 0.033 14.8 0.0 1.2 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Ubiquitin_4 PF18036.1 ORY43404.1 - 0.043 13.9 0.5 0.41 10.7 0.2 1.9 1 1 1 2 2 2 0 Ubiquitin-like domain UN_NPL4 PF11543.8 ORY43404.1 - 0.058 13.9 0.0 0.061 13.8 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 zf-HC5HC2H_2 PF13832.6 ORY43405.1 - 1.2e-30 105.9 13.8 1.2e-30 105.9 13.8 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain Bromodomain PF00439.25 ORY43405.1 - 2.3e-20 72.5 1.0 7.2e-19 67.6 0.1 3.2 3 1 1 4 4 4 1 Bromodomain zf-HC5HC2H PF13771.6 ORY43405.1 - 3.3e-20 72.1 9.8 3.3e-20 72.1 9.8 3.3 3 0 0 3 3 3 2 PHD-like zinc-binding domain PHD_2 PF13831.6 ORY43405.1 - 8.5e-15 54.0 2.1 8.5e-15 54.0 2.1 2.2 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 ORY43405.1 - 4.7e-09 36.0 8.7 4.7e-09 36.0 8.7 3.2 3 0 0 3 3 3 1 PHD-finger EPL1 PF10513.9 ORY43405.1 - 5.8e-07 30.0 28.7 5.8e-07 30.0 28.7 3.3 3 1 0 3 3 3 1 Enhancer of polycomb-like C1_2 PF03107.16 ORY43405.1 - 2.6 8.4 18.7 4.3 7.7 4.4 2.7 2 0 0 2 2 2 0 C1 domain DinB PF05163.12 ORY43406.1 - 1.1e-21 77.5 0.2 2.6e-21 76.3 0.2 1.5 1 1 0 1 1 1 1 DinB family DinB_2 PF12867.7 ORY43406.1 - 3.3e-07 30.8 0.7 3.9e-07 30.6 0.7 1.1 1 0 0 1 1 1 1 DinB superfamily DUF664 PF04978.12 ORY43406.1 - 6.3e-05 23.4 0.9 0.00027 21.4 0.9 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF664) FUSC PF04632.12 ORY43407.1 - 0.21 10.1 8.7 0.23 10.0 8.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2203 PF09969.9 ORY43407.1 - 0.27 12.0 4.9 0.25 12.1 3.5 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) MFS_1 PF07690.16 ORY43408.1 - 8.4e-25 87.4 66.7 5.9e-23 81.4 42.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Flavi_NS4A PF01350.17 ORY43408.1 - 0.035 14.1 0.2 0.035 14.1 0.2 2.4 3 0 0 3 3 3 0 Flavivirus non-structural protein NS4A MFS_1 PF07690.16 ORY43409.1 - 5.4e-18 65.0 42.3 9.6e-16 57.6 29.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 ORY43409.1 - 8.9e-05 21.1 8.5 8.9e-05 21.1 8.5 1.6 2 1 0 2 2 2 1 Transmembrane secretion effector LapA_dom PF06305.11 ORY43409.1 - 1.7 8.5 9.0 6.6 6.6 0.3 3.1 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MFS_1 PF07690.16 ORY43410.1 - 2.1e-22 79.5 47.2 2.3e-15 56.4 28.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 ORY43410.1 - 3.3e-06 25.8 12.3 3.3e-06 25.8 12.3 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_1 PF07690.16 ORY43411.1 - 5.6e-18 65.0 41.8 5.6e-18 65.0 41.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyt-b5 PF00173.28 ORY43412.1 - 1.1e-11 44.6 0.2 1.8e-11 44.0 0.2 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Spectrin PF00435.21 ORY43412.1 - 0.071 13.6 0.1 0.16 12.5 0.1 1.4 2 0 0 2 2 2 0 Spectrin repeat Glyco_hydro_2_C PF02836.17 ORY43413.1 - 4e-12 45.9 0.0 4.3e-11 42.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 ORY43413.1 - 1.1e-05 26.1 0.0 2.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 G10 PF01125.17 ORY43415.1 - 1.7e-66 222.5 4.6 2e-66 222.3 4.6 1.0 1 0 0 1 1 1 1 G10 protein Prp18 PF02840.15 ORY43416.1 - 3.3e-58 195.8 1.8 3.3e-58 195.8 0.1 1.9 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.11 ORY43416.1 - 4.2e-06 26.2 0.6 8e-06 25.3 0.6 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Halogen_Hydrol PF10112.9 ORY43417.1 - 3.5 7.6 5.3 1.9 8.5 0.4 2.4 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF2207 PF09972.9 ORY43417.1 - 10 4.8 9.9 0.97 8.1 1.2 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Fungal_trans PF04082.18 ORY43418.1 - 3.3e-17 62.4 1.4 9e-17 61.0 1.4 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY43418.1 - 8.2e-06 25.8 9.8 1.5e-05 25.0 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 ORY43418.1 - 0.26 11.5 3.0 0.27 11.4 0.6 2.2 2 0 0 2 2 2 0 Gal4-like dimerisation domain DNA_pol_A_exo1 PF01612.20 ORY43419.1 - 6.9e-47 159.4 0.2 1e-46 158.9 0.2 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 ORY43419.1 - 2.5e-13 49.8 0.0 6.3e-13 48.5 0.0 1.7 2 0 0 2 2 2 1 HRDC domain TMEM208_SND2 PF05620.11 ORY43420.1 - 2.8 7.7 6.9 1.4 8.7 0.3 2.9 3 2 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 OAD_gamma PF04277.13 ORY43420.1 - 4.3 8.0 8.2 1.3 9.7 0.7 2.9 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain CAAD PF14159.6 ORY43424.1 - 0.015 15.1 0.1 0.079 12.8 0.0 2.3 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF2500 PF10694.9 ORY43424.1 - 0.051 14.1 0.4 2.9 8.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) DUF4094 PF13334.6 ORY43424.1 - 0.098 13.1 0.6 1 9.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) FTR1 PF03239.14 ORY43425.1 - 0.0003 20.1 1.8 0.00051 19.3 1.8 1.3 1 0 0 1 1 1 1 Iron permease FTR1 family Zn_clus PF00172.18 ORY43427.1 - 9.6e-06 25.6 9.6 9.6e-06 25.6 9.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 ORY43427.1 - 0.0098 15.9 0.8 0.026 14.6 0.8 1.8 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 PAS PF00989.25 ORY43427.1 - 0.033 14.2 0.0 0.08 13.0 0.0 1.8 1 1 0 1 1 1 0 PAS fold Antirestrict PF03230.13 ORY43427.1 - 0.034 14.2 0.0 0.089 12.8 0.0 1.7 1 0 0 1 1 1 0 Antirestriction protein Pro_isomerase PF00160.21 ORY43428.1 - 4.3e-52 176.6 0.0 4.9e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sld7_N PF18636.1 ORY43428.1 - 0.08 13.3 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial morphogenesis protein SLD7 N-terminal domain TIP49 PF06068.13 ORY43430.1 - 4.9e-173 575.2 1.4 6.1e-173 574.9 1.4 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 ORY43430.1 - 2.3e-24 85.3 0.4 6.1e-24 83.9 0.1 2.0 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 ORY43430.1 - 4.7e-12 46.5 0.2 1.6e-07 31.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ORY43430.1 - 8.4e-11 41.9 0.1 1.6e-07 31.2 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORY43430.1 - 2.3e-06 27.9 0.1 0.11 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ORY43430.1 - 9.6e-06 26.1 0.0 0.00084 19.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 ORY43430.1 - 4.2e-05 23.9 0.1 9.2e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ORY43430.1 - 4.3e-05 23.5 0.1 0.0083 16.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 ORY43430.1 - 0.00033 20.3 0.0 0.00061 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY43430.1 - 0.00036 21.1 0.0 0.0023 18.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 ORY43430.1 - 0.00039 19.8 0.2 0.00086 18.7 0.0 1.6 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain Sigma54_activat PF00158.26 ORY43430.1 - 0.0012 18.5 0.1 0.98 9.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.6 ORY43430.1 - 0.0026 18.1 2.8 0.062 13.6 2.8 2.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ORY43430.1 - 0.0028 17.0 0.2 0.01 15.2 0.1 1.9 2 0 0 2 2 2 1 Zeta toxin ResIII PF04851.15 ORY43430.1 - 0.0029 17.6 0.2 0.18 11.8 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 ORY43430.1 - 0.0032 17.5 0.0 1.4 8.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 ORY43430.1 - 0.0034 16.8 0.2 0.12 11.7 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 ORY43430.1 - 0.0064 16.7 0.0 0.037 14.2 0.0 2.2 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 ORY43430.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 ORY43430.1 - 0.012 15.0 0.2 0.16 11.3 0.0 2.3 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 ORY43430.1 - 0.02 14.8 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 ORY43430.1 - 0.02 14.1 0.1 0.04 13.2 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 ORY43430.1 - 0.038 13.5 0.1 0.22 11.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 ORY43430.1 - 0.045 13.7 0.1 0.096 12.7 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 ORY43430.1 - 0.047 14.1 0.5 0.26 11.7 0.1 2.4 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 ORY43430.1 - 0.071 12.5 1.4 0.16 11.4 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_3 PF07726.11 ORY43430.1 - 0.092 12.6 0.0 0.33 10.8 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORY43430.1 - 0.12 12.7 0.0 0.4 11.1 0.0 1.9 2 0 0 2 2 1 0 RNA helicase WD40 PF00400.32 ORY43432.1 - 3.6e-28 97.2 14.4 0.00087 20.1 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 ORY43432.1 - 3e-12 46.1 10.5 3e-12 46.1 10.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Nucleoporin_N PF08801.11 ORY43432.1 - 1.1e-09 37.6 2.8 0.0027 16.5 0.9 3.3 1 1 1 3 3 3 2 Nup133 N terminal like Sina PF03145.16 ORY43432.1 - 1.4e-08 34.9 0.2 3.4e-08 33.7 0.2 1.5 1 0 0 1 1 1 1 Seven in absentia protein family zf-C3HC4 PF00097.25 ORY43432.1 - 5.2e-08 32.6 10.9 5.2e-08 32.6 10.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ANAPC4_WD40 PF12894.7 ORY43432.1 - 1.3e-07 31.8 0.1 0.048 13.9 0.0 3.6 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_2 PF13639.6 ORY43432.1 - 3.1e-07 30.6 9.7 3.1e-07 30.6 9.7 3.0 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY43432.1 - 7.5e-07 29.1 8.0 7.5e-07 29.1 8.0 2.5 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORY43432.1 - 2.6e-06 27.2 8.6 8.4e-06 25.6 8.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Nup160 PF11715.8 ORY43432.1 - 9.1e-06 24.6 9.7 0.013 14.2 0.4 3.9 2 1 2 4 4 4 3 Nucleoporin Nup120/160 zf-RING_6 PF14835.6 ORY43432.1 - 1.2e-05 25.1 2.6 1.2e-05 25.1 2.6 2.4 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 ORY43432.1 - 1.5e-05 25.0 8.5 3e-05 24.1 8.5 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 ORY43432.1 - 7.6e-05 22.9 5.3 7.6e-05 22.9 5.3 2.2 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 ORY43432.1 - 0.00012 22.0 8.6 0.00028 20.8 8.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain WD40_like PF17005.5 ORY43432.1 - 0.00016 21.1 0.1 0.00084 18.8 0.0 1.9 2 0 0 2 2 2 1 WD40-like domain PQQ_3 PF13570.6 ORY43432.1 - 0.00027 21.3 2.1 0.52 10.9 0.1 4.3 5 0 0 5 5 3 1 PQQ-like domain zf-TRAF PF02176.18 ORY43432.1 - 0.00036 21.1 0.3 0.0011 19.6 0.3 1.9 1 0 0 1 1 1 1 TRAF-type zinc finger zf-C3HC4_4 PF15227.6 ORY43432.1 - 0.00054 20.1 7.5 0.00054 20.1 7.5 2.5 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING ELYS-bb PF16687.5 ORY43432.1 - 0.0048 15.6 0.0 0.022 13.4 0.0 1.8 1 1 0 1 1 1 1 beta-propeller of ELYS nucleoporin Prok-RING_4 PF14447.6 ORY43432.1 - 0.005 16.7 9.2 0.013 15.4 9.2 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 ORY43432.1 - 0.015 15.1 6.3 0.029 14.2 6.3 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 ORY43432.1 - 0.019 15.0 3.9 0.08 13.0 3.6 2.3 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PQQ PF01011.21 ORY43432.1 - 0.089 12.8 0.2 0.61 10.1 0.0 2.6 3 0 0 3 3 3 0 PQQ enzyme repeat zf-P11 PF03854.14 ORY43432.1 - 0.69 9.6 7.4 2 8.1 7.4 1.8 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_4 PF14570.6 ORY43432.1 - 0.75 9.6 6.4 2.5 8.0 6.4 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-TRAF_2 PF15965.5 ORY43432.1 - 2.7 8.5 10.2 5 7.7 8.3 2.2 1 1 1 2 2 2 0 TRAF-like zinc-finger zf-C3H2C3 PF17122.5 ORY43432.1 - 6.3 6.9 9.2 16 5.6 9.2 1.8 1 0 0 1 1 1 0 Zinc-finger Ham1p_like PF01725.16 ORY43433.1 - 1.4e-58 198.0 0.0 1.5e-58 197.8 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Tetraspanin PF00335.20 ORY43434.1 - 0.0086 15.8 2.4 0.0086 15.8 2.4 2.3 2 0 0 2 2 2 2 Tetraspanin family DUF4491 PF14898.6 ORY43434.1 - 0.17 12.4 0.1 0.17 12.4 0.1 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4491) Phage_holin_1 PF04531.13 ORY43434.1 - 3.1 8.4 7.9 0.28 11.7 2.1 2.2 2 0 0 2 2 2 0 Bacteriophage holin MBOAT PF03062.19 ORY43437.1 - 1.2e-42 146.5 27.8 1.6e-42 146.1 27.8 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF5422 PF17459.2 ORY43438.1 - 0.44 10.7 5.2 0.69 10.1 1.2 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5422) MBOAT PF03062.19 ORY43439.1 - 2e-46 159.0 18.5 2e-46 159.0 18.5 2.2 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Pkinase PF00069.25 ORY43440.1 - 5.7e-31 107.9 0.0 6.7e-26 91.2 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY43440.1 - 1.4e-18 67.1 0.0 2.1e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY43440.1 - 0.024 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAXIP1_C PF15364.6 ORY43440.1 - 1.8 8.9 11.3 0.072 13.4 1.8 2.5 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF4326 PF14216.6 ORY43441.1 - 2.2e-11 44.3 0.1 2.9e-11 43.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4326) FMO-like PF00743.19 ORY43442.1 - 4.1e-51 174.0 0.0 2.1e-42 145.3 0.0 2.4 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 ORY43442.1 - 3.7e-24 85.5 0.0 7.4e-23 81.3 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY43442.1 - 6.7e-14 51.8 0.0 2.4e-13 50.0 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY43442.1 - 2.9e-08 32.9 0.7 0.00049 18.9 2.8 2.3 2 1 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 ORY43442.1 - 8.2e-08 32.4 0.1 1.8e-05 24.8 0.1 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 ORY43442.1 - 2.5e-07 30.8 4.5 5.9e-07 29.6 2.3 2.8 3 1 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 ORY43442.1 - 3.7e-05 23.1 0.4 0.0026 17.1 1.4 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 ORY43442.1 - 5.2e-05 22.5 0.9 9.7e-05 21.6 0.9 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY43442.1 - 6.6e-05 22.6 0.9 0.049 13.2 1.8 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORY43442.1 - 7.5e-05 23.2 0.0 0.031 14.8 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ORY43442.1 - 0.00019 20.9 0.0 0.52 9.5 0.1 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 ORY43442.1 - 0.0028 17.1 0.0 0.0038 16.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 ORY43442.1 - 0.0038 16.4 0.6 0.012 14.8 0.0 2.1 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 ORY43442.1 - 0.0058 15.9 0.5 0.051 12.8 1.7 1.8 2 0 0 2 2 2 1 FAD binding domain IlvN PF07991.12 ORY43442.1 - 0.079 12.5 0.0 0.44 10.1 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Lycopene_cycl PF05834.12 ORY43442.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 ORY43442.1 - 0.12 11.4 0.1 0.2 10.7 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 ORY43442.1 - 0.25 10.6 0.0 1.2 8.4 0.3 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HET PF06985.11 ORY43443.1 - 3.5e-18 66.4 0.5 6.8e-18 65.4 0.5 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NRDE-2 PF08424.10 ORY43444.1 - 8.3e-78 261.7 0.5 8.3e-78 261.7 0.5 2.0 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 ORY43444.1 - 1.6e-06 28.4 0.7 6.3 7.9 0.0 7.4 6 2 2 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY43444.1 - 0.019 15.4 0.4 2.9 8.5 0.1 4.2 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY43444.1 - 0.031 14.9 0.1 0.22 12.2 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY43444.1 - 0.043 13.7 0.2 0.69 9.9 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY43444.1 - 0.049 13.9 0.9 0.29 11.4 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY43444.1 - 0.058 14.0 0.6 3 8.7 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY43444.1 - 0.14 11.5 0.1 0.26 10.6 0.1 1.3 1 0 0 1 1 1 0 MalT-like TPR region AJAP1_PANP_C PF15298.6 ORY43444.1 - 7.1 6.8 11.0 5.3 7.2 4.3 2.5 2 0 0 2 2 2 0 AJAP1/PANP C-terminus Pro_isomerase PF00160.21 ORY43445.1 - 1.6e-53 181.2 0.0 1.9e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3830 PF12903.7 ORY43445.1 - 0.024 14.3 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3830) DUF5316 PF17247.2 ORY43446.1 - 0.19 11.8 3.1 0.37 10.8 0.2 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5316) ECF_trnsprt PF12822.7 ORY43446.1 - 0.57 10.3 10.0 0.036 14.2 3.9 2.0 2 0 0 2 2 2 0 ECF transporter, substrate-specific component WD40 PF00400.32 ORY43448.1 - 2.8e-07 31.1 6.4 0.00023 21.9 0.1 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat MGAT2 PF05060.14 ORY43448.1 - 0.056 12.5 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) p450 PF00067.22 ORY43451.1 - 1.2e-77 261.6 0.0 1.5e-77 261.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 ORY43452.1 - 2e-66 223.8 0.0 3.4e-66 223.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain POR_N PF01855.19 ORY43452.1 - 2.1e-25 89.9 8.3 6.1e-25 88.3 8.3 1.8 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg NAD_binding_7 PF13241.6 ORY43452.1 - 2.4e-17 63.3 0.2 2.1e-16 60.2 0.0 2.8 3 0 0 3 3 3 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 ORY43452.1 - 1.3e-12 47.2 0.0 8.8e-12 44.5 0.0 2.4 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 ORY43452.1 - 2.4e-12 46.1 0.2 5e-12 45.0 0.2 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central NAD_binding_1 PF00175.21 ORY43452.1 - 2.7e-10 40.8 0.0 6.6e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain TP_methylase PF00590.20 ORY43452.1 - 8.6e-10 38.9 3.6 2.8e-09 37.2 3.6 1.9 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases PFOR_II PF17147.4 ORY43452.1 - 3.5e-07 30.5 0.1 1.3e-06 28.7 0.1 2.0 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II MMS19_C PF12460.8 ORY43452.1 - 0.053 12.6 0.3 0.11 11.7 0.3 1.4 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal PIP5K PF01504.18 ORY43453.1 - 6.7e-41 140.3 0.9 8.6e-34 117.0 0.8 2.3 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 ORY43453.1 - 4.4e-29 101.5 0.0 6.7e-29 100.9 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family baeRF_family5 PF18846.1 ORY43453.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 5 Mito_carr PF00153.27 ORY43454.1 - 1.5e-63 210.7 0.9 8.3e-21 73.7 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 ORY43454.1 - 0.0048 17.3 0.4 1.8 9.0 0.1 2.4 1 1 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family Mito_carr PF00153.27 ORY43455.1 - 4.3e-66 218.9 1.9 2.4e-22 78.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY43455.1 - 1.3 8.1 3.7 6.8 5.8 0.2 2.7 2 2 1 3 3 3 0 Gammaproteobacterial serine protease PTPA PF03095.15 ORY43456.1 - 3e-115 384.8 0.0 3.5e-115 384.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein zf-HC5HC2H_2 PF13832.6 ORY43457.1 - 7.1e-15 55.1 11.2 1.5e-12 47.7 3.2 2.3 2 0 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 ORY43457.1 - 9.4e-12 45.0 13.4 5.2e-10 39.4 2.1 2.6 2 0 0 2 2 2 2 PHD-like zinc-binding domain PHD_2 PF13831.6 ORY43457.1 - 2.4e-06 27.0 8.2 5.3e-06 25.9 1.9 2.8 2 0 0 2 2 2 2 PHD-finger PHD PF00628.29 ORY43457.1 - 3.8e-06 26.7 24.1 3.8e-05 23.5 7.9 3.2 3 1 0 3 3 3 2 PHD-finger XRN_N PF03159.18 ORY43458.1 - 1.1e-61 208.3 0.0 5.4e-61 206.1 0.0 1.8 1 1 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus T3SS_NleG PF06416.12 ORY43458.1 - 0.067 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Effector protein NleG Septin PF00735.18 ORY43459.1 - 2.6e-113 378.0 0.0 3e-113 377.8 0.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 ORY43459.1 - 1.2e-09 38.2 0.0 2.2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY43459.1 - 3.2e-06 27.2 0.3 3.3e-05 23.9 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 ORY43459.1 - 1.2e-05 24.9 0.1 0.0017 17.9 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 ORY43459.1 - 4.1e-05 23.7 0.6 0.051 13.6 0.1 2.5 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 ORY43459.1 - 5e-05 22.7 0.1 9.7e-05 21.8 0.1 1.6 1 1 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 ORY43459.1 - 0.00024 21.6 0.1 0.00051 20.6 0.1 1.8 1 1 0 1 1 1 1 ABC transporter AAA_33 PF13671.6 ORY43459.1 - 0.00062 19.9 0.0 0.0014 18.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 ORY43459.1 - 0.00065 19.5 0.0 0.00096 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.20 ORY43459.1 - 0.0018 17.5 0.2 0.028 13.6 0.0 2.2 1 1 0 2 2 2 1 G-protein alpha subunit RNA_helicase PF00910.22 ORY43459.1 - 0.0052 17.2 0.1 0.019 15.3 0.1 2.0 1 1 0 1 1 1 1 RNA helicase FtsK_SpoIIIE PF01580.18 ORY43459.1 - 0.008 15.5 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Roc PF08477.13 ORY43459.1 - 0.011 15.9 0.0 0.028 14.6 0.0 1.7 2 0 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 ORY43459.1 - 0.011 14.8 0.2 0.032 13.3 0.0 1.9 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) PRK PF00485.18 ORY43459.1 - 0.027 14.2 0.4 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.6 ORY43459.1 - 0.046 13.5 0.1 0.091 12.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 ORY43459.1 - 0.061 13.6 0.1 0.46 10.8 0.0 2.2 3 0 0 3 3 2 0 AAA domain AAA_16 PF13191.6 ORY43459.1 - 0.062 13.7 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.17 ORY43459.1 - 0.067 13.3 0.1 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain NACHT PF05729.12 ORY43459.1 - 0.073 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.15 ORY43459.1 - 0.094 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain FeoB_N PF02421.18 ORY43459.1 - 0.12 11.9 0.2 0.59 9.7 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Viral_helicase1 PF01443.18 ORY43459.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.9 ORY43459.1 - 0.17 11.7 0.0 0.94 9.2 0.0 2.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 ORY43459.1 - 0.17 11.4 0.1 0.49 10.0 0.1 1.8 1 1 0 1 1 1 0 Ras family SRPRB PF09439.10 ORY43459.1 - 0.17 11.3 0.1 0.33 10.3 0.1 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Sigma54_activat PF00158.26 ORY43459.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DOMON PF03351.17 ORY43462.1 - 0.00028 21.1 0.0 0.00036 20.7 0.0 1.2 1 0 0 1 1 1 1 DOMON domain LppX_LprAFG PF07161.13 ORY43462.1 - 0.0049 16.7 0.3 0.19 11.6 0.1 2.1 1 1 0 2 2 2 1 LppX_LprAFG lipoprotein Big_1 PF02369.16 ORY43462.1 - 0.037 14.0 0.4 0.037 14.0 0.4 2.2 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) Tad_C PF09977.9 ORY43462.1 - 1.4 10.2 7.6 0.33 12.2 3.1 2.2 2 1 0 2 2 2 0 Putative Tad-like Flp pilus-assembly PPR_2 PF13041.6 ORY43463.1 - 6.6e-21 74.3 1.2 0.0006 19.9 0.0 7.7 7 1 1 8 8 8 4 PPR repeat family PPR_3 PF13812.6 ORY43463.1 - 1.7e-18 66.5 1.3 0.00017 21.6 0.0 7.4 6 1 2 8 8 8 5 Pentatricopeptide repeat domain PPR_long PF17177.4 ORY43463.1 - 2.2e-06 27.2 0.1 0.5 9.7 0.1 4.2 3 1 1 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 ORY43463.1 - 0.022 15.0 24.1 3.2 8.2 0.9 8.4 9 0 0 9 9 9 0 PPR repeat RPM2 PF08579.11 ORY43463.1 - 0.034 14.6 1.2 5.5 7.4 0.0 3.8 2 2 2 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.6 ORY43463.1 - 0.15 13.0 1.6 27 6.0 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR_1 PF12854.7 ORY43463.1 - 1.2 8.9 4.7 22 4.8 0.0 4.9 6 0 0 6 6 6 0 PPR repeat 3HCDH_N PF02737.18 ORY43464.1 - 2.8e-55 187.0 3.2 3.6e-55 186.6 3.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 ORY43464.1 - 1.2e-36 125.2 0.0 2.2e-36 124.4 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Mon1 PF03164.14 ORY43465.1 - 7e-63 213.1 1.1 3.6e-46 158.0 0.1 2.0 1 1 1 2 2 2 2 Trafficking protein Mon1 DOMON PF03351.17 ORY43469.1 - 0.00079 19.6 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 DOMON domain NMT1_3 PF16868.5 ORY43469.1 - 0.04 13.3 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family DOMON PF03351.17 ORY43470.1 - 0.00039 20.6 1.2 0.0007 19.8 0.1 1.9 2 0 0 2 2 2 1 DOMON domain MGC-24 PF05283.11 ORY43470.1 - 4.2 7.8 11.4 3.6 8.0 10.2 1.5 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin KRAP_IP3R_bind PF14722.6 ORY43472.1 - 0.83 9.4 5.3 9.6 5.9 0.1 2.7 2 1 1 3 3 3 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain Mito_fiss_reg PF05308.11 ORY43473.1 - 0.016 15.3 6.2 0.016 15.3 6.2 2.2 1 1 1 2 2 2 0 Mitochondrial fission regulator SOG2 PF10428.9 ORY43473.1 - 0.49 9.5 20.9 0.57 9.3 20.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Met_10 PF02475.16 ORY43477.1 - 0.17 11.6 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein Ctr PF04145.15 ORY43478.1 - 7.2e-23 81.8 2.7 1e-22 81.3 2.7 1.2 1 0 0 1 1 1 1 Ctr copper transporter family Yip1 PF04893.17 ORY43478.1 - 7.9 6.2 10.9 0.98 9.1 5.7 1.9 1 1 1 2 2 2 0 Yip1 domain Cep57_CLD_2 PF14197.6 ORY43479.1 - 0.0036 17.3 0.2 0.0084 16.2 0.2 1.7 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 Yuri_gagarin PF15934.5 ORY43479.1 - 0.0049 16.8 0.4 0.0053 16.6 0.4 1.2 1 0 0 1 1 1 1 Yuri gagarin Sigma70_ner PF04546.13 ORY43479.1 - 0.0067 16.3 0.4 0.0073 16.2 0.4 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region DegS PF05384.11 ORY43479.1 - 0.0097 15.4 0.1 0.014 14.9 0.1 1.2 1 0 0 1 1 1 1 Sensor protein DegS DUF3450 PF11932.8 ORY43479.1 - 0.01 15.2 3.3 0.011 15.1 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) JIP_LZII PF16471.5 ORY43479.1 - 0.035 14.3 2.1 0.052 13.7 2.1 1.3 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II CCDC-167 PF15188.6 ORY43479.1 - 0.087 13.2 1.0 1.1 9.6 0.7 2.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF563 PF04577.14 ORY43480.1 - 4e-11 43.4 0.0 6.1e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) RIB43A PF05914.12 ORY43481.1 - 4.6e-96 321.8 41.2 6.8e-96 321.3 41.2 1.2 1 0 0 1 1 1 1 RIB43A Ax_dynein_light PF10211.9 ORY43482.1 - 0.087 12.8 7.1 0.12 12.3 7.1 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain DUF724 PF05266.14 ORY43482.1 - 0.1 12.4 3.4 0.14 12.0 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ADIP PF11559.8 ORY43482.1 - 0.12 12.4 5.8 0.16 12.1 5.8 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding GrpE PF01025.19 ORY43482.1 - 0.15 11.7 4.1 0.2 11.3 4.1 1.2 1 0 0 1 1 1 0 GrpE TPR_MLP1_2 PF07926.12 ORY43482.1 - 0.18 11.9 8.6 0.24 11.5 8.6 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Herpes_UL6 PF01763.16 ORY43482.1 - 0.57 8.6 3.9 0.93 7.9 4.0 1.3 1 1 0 1 1 1 0 Herpesvirus UL6 like Ndc1_Nup PF09531.10 ORY43482.1 - 3.4 6.2 5.7 4.4 5.9 5.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UBA PF00627.31 ORY43484.1 - 1.2e-24 85.8 9.7 4.2e-12 45.7 2.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 ORY43484.1 - 1.5e-19 69.5 10.7 1.5e-19 69.5 10.7 1.8 2 0 0 2 2 2 1 XPC-binding domain WIYLD PF10440.9 ORY43484.1 - 0.013 15.2 0.3 2.2 8.2 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain DUF1421 PF07223.11 ORY43484.1 - 0.19 11.6 0.0 5.4 6.9 0.0 2.6 3 0 0 3 3 3 0 UBA-like domain (DUF1421) MAP17 PF15807.5 ORY43485.1 - 0.067 13.4 1.1 15 5.9 0.0 2.6 3 0 0 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF2207 PF09972.9 ORY43485.1 - 3.7 6.2 10.1 4.8 5.8 2.2 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Phage_holin_3_6 PF07332.11 ORY43485.1 - 7.9 6.6 10.2 1.7 8.7 3.2 2.6 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Claudin_3 PF06653.11 ORY43485.1 - 8.5 6.3 15.8 0.036 14.0 3.2 2.4 2 0 0 2 2 2 0 Tight junction protein, Claudin-like Usp PF00582.26 ORY43486.1 - 1.5e-13 51.4 0.0 2.1e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family KAR9 PF08580.10 ORY43487.1 - 0.87 8.1 7.7 0.98 7.9 7.7 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Hira PF07569.11 ORY43488.1 - 0.017 14.8 0.2 0.033 13.9 0.2 1.5 1 0 0 1 1 1 0 TUP1-like enhancer of split Spo0A_C PF08769.11 ORY43488.1 - 0.074 13.2 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal Csm2_III-A PF03750.13 ORY43488.1 - 0.1 13.4 0.1 1.6 9.6 0.0 2.2 2 0 0 2 2 2 0 Csm2 Type III-A DUF3446 PF11928.8 ORY43489.1 - 0.0071 16.6 0.2 0.0071 16.6 0.2 1.8 2 1 0 2 2 2 1 Early growth response N-terminal domain API5 PF05918.11 ORY43490.1 - 1.8e-26 93.1 0.2 2e-26 92.9 0.2 1.0 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.6 ORY43490.1 - 0.002 18.5 0.0 0.0026 18.1 0.0 1.3 1 0 0 1 1 1 1 HEAT repeats HEAT PF02985.22 ORY43490.1 - 0.0056 16.8 0.0 0.017 15.3 0.0 1.8 1 0 0 1 1 1 1 HEAT repeat Cecropin PF00272.19 ORY43490.1 - 0.085 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Cecropin family API5 PF05918.11 ORY43491.1 - 1.8 7.3 9.7 1.2 7.9 2.1 3.3 3 1 0 3 3 3 0 Apoptosis inhibitory protein 5 (API5) cNMP_binding PF00027.29 ORY43492.1 - 1.1e-42 144.0 0.2 7.5e-21 74.0 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain cNMP_binding PF00027.29 ORY43493.1 - 2.1e-40 136.7 0.2 1.8e-21 76.0 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Endomucin PF07010.12 ORY43493.1 - 0.44 10.5 8.7 0.68 9.9 8.7 1.2 1 0 0 1 1 1 0 Endomucin ORC6 PF05460.13 ORY43493.1 - 2.8 7.1 9.9 4 6.6 9.9 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Guanylate_cyc PF00211.20 ORY43494.1 - 4.5e-68 228.5 6.1 3.5e-34 118.0 0.5 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain cNMP_binding PF00027.29 ORY43495.1 - 3.5e-14 52.6 0.0 7.6e-14 51.6 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain cNMP_binding PF00027.29 ORY43496.1 - 3e-06 27.2 0.1 5.8e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF5570 PF17731.1 ORY43496.1 - 0.087 12.9 2.8 4 7.5 4.9 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5570) Condensation PF00668.20 ORY43497.1 - 1.3e-09 37.2 0.0 2.2e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Condensation domain WES_acyltransf PF03007.16 ORY43497.1 - 0.0059 16.4 0.1 0.012 15.4 0.1 1.5 1 1 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Ank_2 PF12796.7 ORY43498.1 - 0.0002 21.9 0.0 0.00038 21.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY43498.1 - 0.00043 20.8 0.1 0.01 16.4 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) AtpR PF12966.7 ORY43499.1 - 1.6 9.3 3.8 0.44 11.0 0.4 1.8 2 0 0 2 2 2 0 N-ATPase, AtpR subunit SRR1 PF07985.12 ORY43501.1 - 2.3e-16 59.6 0.2 3.9e-16 58.8 0.2 1.4 1 0 0 1 1 1 1 SRR1 Ribosomal_L28e PF01778.17 ORY43503.1 - 2.8e-38 131.2 2.7 2.8e-38 131.2 2.7 2.6 3 0 0 3 3 3 1 Ribosomal L28e protein family Mak16 PF04874.14 ORY43503.1 - 1.3e-23 83.4 12.5 2.7e-23 82.5 12.5 1.5 1 0 0 1 1 1 1 Mak16 protein C-terminal region Exonuc_VII_L PF02601.15 ORY43503.1 - 0.00081 19.0 3.0 0.0011 18.7 3.0 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit RNA_pol_3_Rpc31 PF11705.8 ORY43503.1 - 0.57 10.4 9.4 0.9 9.8 9.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 NPCC PF08058.11 ORY43505.1 - 0.02 14.9 0.1 0.052 13.6 0.1 1.7 1 0 0 1 1 1 0 Nuclear pore complex component MMR_HSR1 PF01926.23 ORY43506.1 - 0.00026 21.0 0.1 0.00094 19.2 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GAS PF13851.6 ORY43506.1 - 0.00069 19.0 4.1 0.0067 15.8 0.2 2.5 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding AIG1 PF04548.16 ORY43506.1 - 0.0021 17.4 4.3 0.0035 16.7 0.4 3.1 3 1 1 4 4 4 1 AIG1 family Vps5 PF09325.10 ORY43506.1 - 0.025 14.1 7.7 0.27 10.8 0.2 3.0 3 0 0 3 3 3 0 Vps5 C terminal like ATG16 PF08614.11 ORY43506.1 - 0.23 11.7 2.5 0.39 10.9 0.1 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 ORY43506.1 - 0.45 10.5 4.7 9 6.3 0.4 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF848 PF05852.11 ORY43506.1 - 0.65 10.1 3.3 7 6.8 0.2 2.9 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Dynamin_N PF00350.23 ORY43506.1 - 0.71 9.9 8.4 0.39 10.8 4.0 2.6 2 1 0 2 2 2 0 Dynamin family APG6_N PF17675.1 ORY43506.1 - 0.81 10.2 4.6 4.8 7.7 0.2 2.9 3 0 0 3 3 3 0 Apg6 coiled-coil region Spc7 PF08317.11 ORY43506.1 - 1.2 8.0 11.2 1.2 8.0 0.8 2.8 3 0 0 3 3 3 0 Spc7 kinetochore protein Ank_2 PF12796.7 ORY43507.1 - 1.9e-15 57.2 0.0 5.9e-09 36.4 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Lipase_3 PF01764.25 ORY43507.1 - 3.9e-09 36.5 0.0 8.8e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Ank_4 PF13637.6 ORY43507.1 - 4.7e-08 33.4 0.0 0.0046 17.5 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY43507.1 - 7e-07 29.1 0.0 0.39 11.4 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 ORY43507.1 - 1.7e-06 28.2 0.1 0.12 12.8 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY43507.1 - 3.8e-06 27.1 0.0 0.53 10.8 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat DUF4436 PF14494.6 ORY43509.1 - 0.0099 15.2 0.7 0.012 15.0 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) RSN1_7TM PF02714.15 ORY43510.1 - 1.7e-58 198.2 22.6 2.9e-58 197.4 22.6 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 ORY43510.1 - 1e-12 48.7 0.0 1.6e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 ORY43510.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Extracellular tail, of 10TM putative phosphate transporter cNMP_binding PF00027.29 ORY43511.1 - 8e-16 57.9 0.0 1.9e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CRISPR_Cas6 PF10040.9 ORY43511.1 - 0.14 12.8 0.0 0.33 11.6 0.0 1.7 1 0 0 1 1 1 0 CRISPR-associated endoribonuclease Cas6 DUF4337 PF14235.6 ORY43511.1 - 0.15 12.2 0.5 0.4 10.8 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DnaJ-X PF14308.6 ORY43514.1 - 2e-41 141.7 0.8 2.6e-37 128.3 0.2 2.4 2 0 0 2 2 2 2 X-domain of DnaJ-containing DnaJ PF00226.31 ORY43514.1 - 3.5e-26 91.1 0.3 9.4e-26 89.7 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain CN_hydrolase PF00795.22 ORY43515.1 - 0.013 14.8 0.2 0.015 14.6 0.2 1.1 1 0 0 1 1 1 0 Carbon-nitrogen hydrolase DUF4150 PF13665.6 ORY43515.1 - 0.063 13.4 3.6 0.073 13.2 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4150) zf-WRNIP1_ubi PF18279.1 ORY43515.1 - 0.19 12.4 0.2 0.19 12.4 0.2 1.9 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-H2C2_2 PF13465.6 ORY43516.1 - 5.4e-11 42.4 22.3 2.8e-05 24.3 1.7 4.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY43516.1 - 2.8e-10 40.1 22.6 0.0092 16.7 2.6 5.0 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY43516.1 - 6.4e-10 38.9 23.5 0.00018 21.8 0.5 4.9 5 0 0 5 5 5 3 Zinc finger, C2H2 type TFIIA PF03153.13 ORY43516.1 - 4.8e-06 26.8 12.3 5.9e-06 26.6 12.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit zf-C2H2_6 PF13912.6 ORY43516.1 - 0.0018 18.2 15.7 2.1 8.5 2.1 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY43516.1 - 0.0029 17.9 11.9 0.015 15.6 4.8 2.6 1 1 1 2 2 2 1 C2H2-type zinc ribbon NOA36 PF06524.12 ORY43516.1 - 0.0094 15.3 11.6 0.013 14.9 11.6 1.2 1 0 0 1 1 1 1 NOA36 protein FOXP-CC PF16159.5 ORY43516.1 - 0.033 14.8 0.4 0.033 14.8 0.4 3.1 3 1 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2_aberr PF17017.5 ORY43516.1 - 0.36 10.9 8.3 1.7 8.8 0.3 2.8 2 1 1 3 3 3 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 ORY43516.1 - 0.37 11.1 11.7 8.6 6.8 0.5 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_9 PF16293.5 ORY43516.1 - 0.66 9.9 2.9 73 3.3 0.1 3.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) zinc_ribbon_15 PF17032.5 ORY43516.1 - 1.4 9.7 6.1 7.5 7.4 1.7 2.4 1 1 0 2 2 2 0 zinc-ribbon family DDE_Tnp_ISL3 PF01610.17 ORY43517.1 - 0.052 13.3 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Transposase Sel1 PF08238.12 ORY43519.1 - 4.6e-103 335.3 74.4 2.6e-10 40.6 0.4 11.6 12 0 0 12 12 11 11 Sel1 repeat Pkinase PF00069.25 ORY43519.1 - 4.1e-24 85.4 0.0 5.9e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY43519.1 - 8.5e-19 67.8 0.0 1.3e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_19 PF14559.6 ORY43519.1 - 1.4e-05 25.5 40.3 1 9.9 1.5 10.0 6 4 2 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY43519.1 - 1.5e-05 25.6 42.0 0.1 13.2 0.6 8.5 3 3 5 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.6 ORY43519.1 - 0.00046 20.6 39.0 0.44 11.3 0.2 10.6 11 1 0 11 11 10 2 Tetratricopeptide repeat RNA_pol_N PF01194.17 ORY43519.1 - 0.00086 19.6 9.9 1.5e+02 2.8 0.0 7.9 7 1 1 8 8 8 0 RNA polymerases N / 8 kDa subunit APH PF01636.23 ORY43519.1 - 0.0022 18.0 0.0 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family TPR_1 PF00515.28 ORY43519.1 - 0.0026 17.5 71.2 0.88 9.5 0.2 16.3 19 1 0 19 19 18 2 Tetratricopeptide repeat Raptor_N PF14538.6 ORY43519.1 - 0.0077 16.2 9.8 1.1e+02 2.8 0.0 7.5 3 1 6 9 9 9 0 Raptor N-terminal CASPase like domain SPO22 PF08631.10 ORY43519.1 - 0.024 14.1 17.3 0.13 11.7 0.2 6.3 4 2 4 8 8 8 0 Meiosis protein SPO22/ZIP4 like TPR_11 PF13414.6 ORY43519.1 - 0.033 13.9 69.3 1.9 8.3 0.2 13.0 13 2 0 13 13 12 0 TPR repeat Pox_ser-thr_kin PF05445.11 ORY43519.1 - 0.059 12.3 0.1 0.097 11.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF2554 PF10829.8 ORY43519.1 - 0.07 13.5 23.2 19 5.7 0.1 9.1 3 2 8 11 11 9 0 Protein of unknown function (DUF2554) Kdo PF06293.14 ORY43519.1 - 0.076 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY43519.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase TPR_2 PF07719.17 ORY43519.1 - 0.19 11.9 56.1 3 8.2 0.5 13.8 14 1 0 14 14 14 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY43519.1 - 0.35 11.0 25.7 68 3.8 0.1 9.8 10 1 1 11 11 11 0 Tetratricopeptide repeat SQAPI PF16845.5 ORY43519.1 - 0.7 10.3 24.0 0.53 10.7 0.2 6.8 3 3 5 8 8 8 0 Aspartic acid proteinase inhibitor NRBF2_MIT PF17169.4 ORY43519.1 - 0.89 9.8 13.2 3 8.1 0.1 6.2 7 0 0 7 7 7 0 MIT domain of nuclear receptor-binding factor 2 KxDL PF10241.9 ORY43520.1 - 0.019 15.2 0.9 0.22 11.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF3450 PF11932.8 ORY43521.1 - 0.00077 18.8 1.2 0.001 18.4 1.0 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) Nsp1_C PF05064.13 ORY43521.1 - 0.00095 19.0 1.0 0.0011 18.8 1.0 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region ZapB PF06005.12 ORY43521.1 - 0.0011 19.4 4.4 0.0014 19.0 4.4 1.3 1 1 0 1 1 1 1 Cell division protein ZapB BLOC1_2 PF10046.9 ORY43521.1 - 0.0022 18.2 0.8 0.0029 17.9 0.8 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 ORY43521.1 - 0.0029 17.5 0.9 0.0033 17.3 0.9 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 BST2 PF16716.5 ORY43521.1 - 0.0042 17.6 2.2 0.0053 17.3 2.2 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 GAS PF13851.6 ORY43521.1 - 0.0057 16.0 2.8 0.0064 15.9 2.8 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding YabA PF06156.13 ORY43521.1 - 0.018 15.6 1.2 0.022 15.4 1.2 1.2 1 0 0 1 1 1 0 Initiation control protein YabA CCDC92 PF14916.6 ORY43521.1 - 0.019 14.7 3.5 0.034 13.9 3.3 1.6 1 1 0 1 1 1 0 Coiled-coil domain of unknown function Cluap1 PF10234.9 ORY43521.1 - 0.019 14.4 1.4 0.02 14.3 1.4 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Herpes_UL6 PF01763.16 ORY43521.1 - 0.019 13.5 1.5 0.02 13.5 1.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like HlyD_D23 PF16576.5 ORY43521.1 - 0.027 13.7 1.0 0.029 13.6 1.0 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion TMF_DNA_bd PF12329.8 ORY43521.1 - 0.034 14.1 1.1 0.034 14.1 1.1 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Rab_bind PF16704.5 ORY43521.1 - 0.034 14.2 0.3 2.8 8.1 0.1 2.3 1 1 1 2 2 2 0 Rab binding domain Sec34 PF04136.15 ORY43521.1 - 0.035 14.0 1.3 0.039 13.8 1.3 1.1 1 0 0 1 1 1 0 Sec34-like family APG6_N PF17675.1 ORY43521.1 - 0.046 14.3 2.7 0.062 13.8 2.7 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF948 PF06103.11 ORY43521.1 - 0.077 13.3 0.4 0.11 12.8 0.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 ORY43521.1 - 0.13 12.5 2.9 0.52 10.5 2.8 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 ORY43521.1 - 0.14 12.4 1.7 0.27 11.5 1.7 1.5 1 0 0 1 1 1 0 Haemolysin XhlA USP8_interact PF08941.10 ORY43521.1 - 0.15 11.9 1.9 0.18 11.6 1.9 1.1 1 0 0 1 1 1 0 USP8 interacting SlyX PF04102.12 ORY43521.1 - 0.27 11.9 4.6 2.1 9.0 4.6 2.1 1 1 0 1 1 1 0 SlyX DivIC PF04977.15 ORY43521.1 - 0.77 9.6 4.7 3.7 7.4 4.7 2.0 1 1 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 ORY43521.1 - 0.98 9.6 3.9 3.9 7.6 1.2 2.3 1 1 1 2 2 2 0 Basic region leucine zipper Pkinase_Tyr PF07714.17 ORY43594.1 - 5.3e-08 32.5 0.0 6.1e-08 32.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORY43594.1 - 7.6e-07 28.7 0.1 8.5e-07 28.6 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Ribosomal_S19e PF01090.19 ORY43594.1 - 0.0046 16.7 0.0 0.0052 16.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19e BMC PF00936.19 ORY43594.1 - 0.0069 16.4 0.0 0.0086 16.0 0.0 1.2 1 0 0 1 1 1 1 BMC domain DUF1768 PF08719.11 ORY43595.1 - 3.6e-31 108.6 0.0 5.9e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) TolA_bind_tri PF16331.5 ORY43596.1 - 0.085 13.0 3.4 0.26 11.4 3.4 1.9 1 0 0 1 1 1 0 TolA binding protein trimerisation dbPDZ_assoc PF16610.5 ORY43596.1 - 0.72 10.1 2.8 1.2 9.4 0.5 2.2 2 0 0 2 2 2 0 Unstructured region between two PDZ domains on Dlg5 Radical_SAM PF04055.21 ORY43597.1 - 4.7e-15 56.4 0.0 3.5e-14 53.5 0.0 2.3 2 1 1 3 3 3 1 Radical SAM superfamily Fer4_14 PF13394.6 ORY43597.1 - 6e-05 23.2 0.0 0.00014 22.0 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 ORY43597.1 - 0.049 13.9 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 4Fe-4S single cluster domain YjcB PF15940.5 ORY43597.1 - 0.17 12.1 0.5 1.3 9.3 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function DUF2431 PF10354.9 ORY43598.1 - 1.3e-25 90.6 0.0 1.8e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) zf-C2H2_4 PF13894.6 ORY43598.1 - 0.0087 16.8 4.5 0.065 14.1 0.2 4.1 5 0 0 5 5 5 1 C2H2-type zinc finger zf-Di19 PF05605.12 ORY43598.1 - 0.016 15.4 0.1 9 6.7 0.0 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 ORY43598.1 - 0.019 15.4 1.0 0.13 12.7 0.1 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type Lipase_3 PF01764.25 ORY43600.1 - 5.6e-34 117.0 0.0 1e-33 116.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 ORY43600.1 - 0.051 12.8 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PH_2 PF08458.10 ORY43600.1 - 0.15 12.4 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Plant pleckstrin homology-like region Lipase_3 PF01764.25 ORY43601.1 - 1.3e-08 34.8 0.0 1.2e-07 31.7 0.0 2.5 1 1 0 1 1 1 1 Lipase (class 3) MMR_HSR1 PF01926.23 ORY43601.1 - 0.0013 18.8 0.0 0.019 15.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 ORY43601.1 - 0.12 11.8 0.2 0.37 10.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Ribonuclease_T2 PF00445.18 ORY43604.1 - 5.1e-29 101.8 0.3 5.9e-29 101.6 0.3 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family FAD_binding_8 PF08022.12 ORY43605.1 - 0.08 13.0 1.2 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 FAD-binding domain EIIBC-GUT_N PF03612.14 ORY43606.1 - 5.2 6.8 5.9 1.7 8.3 0.1 2.2 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Peroxidase_2 PF01328.17 ORY43607.1 - 5e-50 170.6 0.0 6.1e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 DER1 PF04511.15 ORY43608.1 - 3.7e-43 147.7 8.2 4.4e-43 147.4 8.2 1.0 1 0 0 1 1 1 1 Der1-like family Ribonuclease_T2 PF00445.18 ORY43609.1 - 1.6e-29 103.4 0.3 2e-29 103.1 0.3 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Ribonuclease_T2 PF00445.18 ORY43610.1 - 1.3e-32 113.5 0.2 1.9e-32 113.0 0.2 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Solute_trans_a PF03619.16 ORY43611.1 - 4.2e-42 144.5 9.4 5e-42 144.3 9.4 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4293 PF14126.6 ORY43611.1 - 0.71 10.1 8.1 0.093 13.0 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Solute_trans_a PF03619.16 ORY43612.1 - 3.7e-81 272.5 25.2 4.4e-81 272.3 25.2 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha MscL PF01741.18 ORY43612.1 - 0.032 14.5 2.1 0.055 13.8 0.3 2.2 2 1 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL DPM3 PF08285.11 ORY43612.1 - 6.9 6.9 12.2 0.17 12.1 4.8 2.2 2 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) IL34 PF15036.6 ORY43614.1 - 0.039 14.0 0.2 0.043 13.9 0.2 1.1 1 0 0 1 1 1 0 Interleukin 34 CRA PF06589.11 ORY43614.1 - 0.041 14.0 0.2 0.053 13.6 0.2 1.1 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) DUF2721 PF11026.8 ORY43614.1 - 0.05 13.5 0.1 0.063 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) TctB PF07331.11 ORY43616.1 - 0.92 9.8 11.5 0.21 11.8 0.6 2.9 1 1 2 3 3 3 0 Tripartite tricarboxylate transporter TctB family DUF2070 PF09843.9 ORY43616.1 - 5.2 5.2 6.4 6.3 5.0 6.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Cpn60_TCP1 PF00118.24 ORY43617.1 - 1.2e-75 255.1 6.1 7.9e-75 252.3 6.1 2.2 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF5442 PF17514.2 ORY43617.1 - 0.036 14.3 0.0 0.081 13.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5442) CRM1_repeat PF18777.1 ORY43617.1 - 0.062 12.8 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat DUF829 PF05705.14 ORY43620.1 - 4.6e-09 36.5 0.0 4.9e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Collagen PF01391.18 ORY43621.1 - 0.027 14.2 5.5 0.054 13.3 5.5 1.5 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) WD40 PF00400.32 ORY43622.1 - 1.4e-09 38.4 0.6 0.015 16.1 0.0 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat AmiS_UreI PF02293.15 ORY43627.1 - 0.065 13.2 0.0 0.07 13.1 0.0 1.0 1 0 0 1 1 1 0 AmiS/UreI family transporter Metallophos_2 PF12850.7 ORY43628.1 - 0.0014 18.8 0.3 0.049 13.8 0.0 2.5 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Myc_N PF01056.18 ORY43628.1 - 0.041 13.8 0.9 0.048 13.5 0.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region FAM176 PF14851.6 ORY43628.1 - 0.13 11.9 1.2 0.19 11.4 1.2 1.2 1 0 0 1 1 1 0 FAM176 family WRNPLPNID PF15017.6 ORY43628.1 - 0.13 13.2 8.4 0.23 12.4 8.4 1.4 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box BioY PF02632.14 ORY43630.1 - 0.001 19.1 2.1 0.0014 18.7 2.1 1.2 1 0 0 1 1 1 1 BioY family Erf4 PF10256.9 ORY43631.1 - 0.0019 18.3 0.0 0.0035 17.5 0.0 1.5 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DHHW PF14286.6 ORY43632.1 - 0.09 12.1 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 DHHW protein Erf4 PF10256.9 ORY43635.1 - 0.0005 20.2 0.5 0.07 13.2 0.0 2.2 1 1 1 2 2 2 2 Golgin subfamily A member 7/ERF4 family SdpI PF13630.6 ORY43636.1 - 0.06 13.5 2.3 0.11 12.7 2.3 1.4 1 0 0 1 1 1 0 SdpI/YhfL protein family DUF2842 PF11003.8 ORY43637.1 - 0.0054 17.0 1.5 0.0085 16.3 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2842) Peroxidase_2 PF01328.17 ORY43638.1 - 8e-44 150.4 0.0 9.9e-44 150.1 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Peroxidase_2 PF01328.17 ORY43639.1 - 7.1e-52 176.7 0.0 8.7e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Glycos_transf_2 PF00535.26 ORY43642.1 - 0.0046 16.8 0.0 0.0094 15.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ORY43642.1 - 0.034 14.0 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 T2SSE PF00437.20 ORY43642.1 - 0.095 11.7 0.2 0.13 11.3 0.2 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF5335 PF17269.2 ORY43642.1 - 0.11 12.4 0.3 0.26 11.2 0.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5335) 5-nucleotidase PF06189.12 ORY43642.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 5'-nucleotidase adh_short PF00106.25 ORY43644.1 - 1.7e-19 70.0 0.3 2.7e-18 66.1 0.4 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY43644.1 - 1.1e-11 44.8 0.9 6.5e-11 42.2 0.8 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY43644.1 - 1.8e-06 28.0 0.6 2.8e-06 27.4 0.6 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORY43644.1 - 0.00078 19.4 0.1 0.001 19.0 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding F420_oxidored PF03807.17 ORY43644.1 - 0.00084 19.9 0.4 0.0015 19.1 0.4 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 ORY43644.1 - 0.004 17.2 0.1 0.0075 16.3 0.1 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 ORY43644.1 - 0.023 15.0 0.4 0.035 14.4 0.4 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 ORY43644.1 - 0.05 13.1 0.1 0.064 12.7 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 ORY43644.1 - 0.082 12.2 0.3 0.12 11.7 0.3 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Fringe PF02434.16 ORY43645.1 - 0.0036 16.8 0.1 0.0045 16.4 0.1 1.2 1 0 0 1 1 1 1 Fringe-like Glyco_transf_34 PF05637.12 ORY43645.1 - 0.012 15.4 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Galactosyl_T PF01762.21 ORY43645.1 - 0.013 15.3 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Galactosyltransferase ABC2_membrane_5 PF13346.6 ORY43647.1 - 0.0053 16.3 5.7 0.0072 15.9 5.7 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein FA_desaturase PF00487.24 ORY43647.1 - 0.031 14.1 0.0 0.035 13.9 0.0 1.1 1 0 0 1 1 1 0 Fatty acid desaturase DUF2069 PF09842.9 ORY43647.1 - 0.09 13.0 2.8 0.15 12.3 2.8 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2069) DUF2626 PF11117.8 ORY43647.1 - 0.21 12.3 3.2 0.32 11.7 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2626) Glyco_hydro_46 PF01374.18 ORY43649.1 - 2.8e-15 56.5 0.0 2.4e-10 40.4 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 46 CH PF00307.31 ORY43650.1 - 0.059 13.6 0.1 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 Calponin homology (CH) domain RhoGEF PF00621.20 ORY43651.1 - 1.8e-09 38.1 0.1 4e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 RhoGEF domain Plavaka PF18759.1 ORY43653.1 - 6.2e-42 144.0 0.0 9e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Plavaka transposase NCE101 PF11654.8 ORY43653.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Non-classical export protein 1 NifW PF03206.14 ORY43653.1 - 0.097 13.2 0.2 0.26 11.8 0.2 1.7 1 0 0 1 1 1 0 Nitrogen fixation protein NifW Alpha_kinase PF02816.18 ORY43654.1 - 4.8e-05 23.6 0.0 0.00014 22.1 0.0 1.8 1 0 0 1 1 1 1 Alpha-kinase family CxC6 PF18721.1 ORY43654.1 - 0.12 12.7 3.0 0.39 11.0 3.0 1.9 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases NPC1_N PF16414.5 ORY43654.1 - 0.23 11.0 5.2 0.39 10.2 5.2 1.3 1 0 0 1 1 1 0 Niemann-Pick C1 N terminus HTH_21 PF13276.6 ORY43655.1 - 0.0021 18.2 2.5 0.0074 16.4 0.0 2.7 3 0 0 3 3 3 1 HTH-like domain HTH_33 PF13592.6 ORY43655.1 - 0.051 13.2 2.7 0.94 9.2 0.1 3.3 3 0 0 3 3 3 0 Winged helix-turn helix rve PF00665.26 ORY43655.1 - 0.083 13.1 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain RNase_PH PF01138.21 ORY43657.1 - 3.5e-31 108.4 0.0 4.8e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 LUC7 PF03194.15 ORY43659.1 - 0.016 14.9 0.9 0.018 14.7 0.9 1.1 1 0 0 1 1 1 0 LUC7 N_terminus DUF3091 PF11291.8 ORY43659.1 - 0.083 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3091) Peptidase_S8 PF00082.22 ORY43661.1 - 6.2e-32 111.0 1.0 1.3e-31 110.0 1.0 1.5 1 1 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 ORY43661.1 - 1.7e-21 76.0 0.3 8.9e-21 73.7 0.1 2.1 2 0 0 2 2 2 1 Proprotein convertase P-domain S8_pro-domain PF16470.5 ORY43661.1 - 0.00017 22.2 0.0 0.00036 21.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase S8 pro-domain Peptidase_S8_N PF16361.5 ORY43661.1 - 0.084 13.4 0.1 0.15 12.5 0.1 1.4 1 0 0 1 1 1 0 N-terminal of Subtilase family MFS18 PF17352.2 ORY43661.1 - 0.35 11.3 4.7 6.1 7.3 0.6 2.6 2 0 0 2 2 2 0 Male Flower Specific protein 18 Vps35 PF03635.17 ORY43662.1 - 4.4e-225 749.5 0.2 1.4e-172 575.9 0.0 2.7 2 1 0 2 2 2 2 Vacuolar protein sorting-associated protein 35 Mob1_phocein PF03637.17 ORY43662.1 - 0.18 11.8 0.1 2.6 8.1 0.0 2.5 2 0 0 2 2 2 0 Mob1/phocein family CAP_N PF01213.19 ORY43663.1 - 0.046 13.2 3.6 0.063 12.8 1.4 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal CYSTM PF12734.7 ORY43663.1 - 0.47 10.8 1.2 0.94 9.9 0.1 2.1 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance CRAL_TRIO PF00650.20 ORY43665.1 - 2.8e-21 75.9 0.0 6e-21 74.8 0.0 1.5 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORY43665.1 - 3.6e-08 33.5 0.3 7.1e-08 32.5 0.3 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Antigen_Bd37 PF11641.8 ORY43665.1 - 0.015 14.8 0.1 0.024 14.2 0.1 1.3 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein A1_Propeptide PF07966.12 ORY43665.1 - 0.19 11.7 0.1 0.43 10.5 0.1 1.6 1 0 0 1 1 1 0 A1 Propeptide Imm57 PF15596.6 ORY43666.1 - 0.34 11.2 4.4 1.1e+02 3.2 0.0 3.9 4 0 0 4 4 4 0 Immunity protein 57 T4_Rnl2_C PF18043.1 ORY43667.1 - 0.0078 16.3 0.0 0.012 15.8 0.0 1.2 1 0 0 1 1 1 1 T4 RNA ligase 2 C-terminal Kelch_5 PF13854.6 ORY43669.1 - 1.1e-09 38.1 5.5 0.022 14.7 0.0 5.6 5 1 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 ORY43669.1 - 0.0004 20.6 13.3 7.5 7.0 4.0 5.4 5 1 0 5 5 5 3 Kelch motif Kelch_4 PF13418.6 ORY43669.1 - 0.69 10.0 0.0 0.69 10.0 0.0 4.2 5 1 0 5 5 5 0 Galactose oxidase, central domain DUF724 PF05266.14 ORY43670.1 - 1.3 8.8 6.2 2.9 7.7 5.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Tim54 PF11711.8 ORY43671.1 - 9.3e-34 116.8 0.0 3.5e-25 88.6 0.0 2.1 1 1 1 2 2 2 2 Inner membrane protein import complex subunit Tim54 Acetyltransf_9 PF13527.7 ORY43673.1 - 7.1e-05 22.9 0.1 0.00034 20.7 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain OCRE PF17780.1 ORY43674.1 - 0.001 19.0 0.3 0.88 9.6 0.0 2.7 2 1 0 2 2 2 2 OCRE domain HTH_Tnp_ISL3 PF13542.6 ORY43674.1 - 0.022 14.1 0.1 5.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 UPF0547 PF10571.9 ORY43674.1 - 6.4 7.0 7.4 26 5.0 0.4 3.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 DUF438 PF04282.13 ORY43676.1 - 1.3 9.0 6.0 0.54 10.3 0.6 2.8 2 2 1 3 3 3 0 Family of unknown function (DUF438) FSA_C PF10479.9 ORY43677.1 - 0.041 12.0 2.1 0.044 11.9 2.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus FAD_binding_3 PF01494.19 ORY43678.1 - 5e-09 35.9 4.8 0.00092 18.6 0.6 3.5 3 1 0 3 3 3 2 FAD binding domain DAO PF01266.24 ORY43678.1 - 0.00017 21.3 0.4 0.00017 21.3 0.4 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY43678.1 - 0.0047 16.2 0.1 0.0047 16.2 0.1 1.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY43678.1 - 0.0081 16.7 0.4 0.023 15.2 0.4 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY43678.1 - 0.015 15.5 3.2 0.024 14.9 0.2 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORY43678.1 - 0.038 13.1 0.4 0.066 12.3 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 ORY43678.1 - 0.056 12.5 0.2 0.089 11.8 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 ORY43678.1 - 0.15 11.3 0.2 0.28 10.4 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_N PF08240.12 ORY43680.1 - 8.8e-10 38.4 0.0 1.5e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY43680.1 - 1.8e-09 37.7 0.0 3.7e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY43680.1 - 0.0011 20.1 0.1 0.0028 18.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF4864 PF16156.5 ORY43680.1 - 0.12 13.1 0.0 0.26 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) AAA PF00004.29 ORY43681.1 - 6.3e-05 23.4 0.1 0.00059 20.3 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PD40 PF07676.12 ORY43682.1 - 4e-05 23.4 0.1 0.009 15.9 0.1 3.2 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 ORY43682.1 - 0.00019 21.6 0.0 0.87 9.9 0.0 4.1 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain SGL PF08450.12 ORY43682.1 - 0.037 13.6 0.0 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region WD40 PF00400.32 ORY43682.1 - 0.092 13.7 0.5 92 4.2 0.0 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat DUF2415 PF10313.9 ORY43682.1 - 0.14 12.1 0.1 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) S-AdoMet_synt_C PF02773.16 ORY43685.1 - 4.3e-53 179.0 7.6 7e-53 178.3 3.6 2.8 2 1 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 ORY43685.1 - 3e-46 156.6 0.0 5.3e-46 155.8 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 ORY43685.1 - 1.8e-44 150.4 0.3 4e-44 149.3 0.3 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 ORY43685.1 - 0.043 12.6 0.4 0.11 11.3 0.2 1.7 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Homeodomain PF00046.29 ORY43690.1 - 5e-14 51.9 2.8 1.1e-13 50.7 2.8 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY43690.1 - 0.061 13.2 0.2 0.16 11.9 0.2 1.7 1 0 0 1 1 1 0 Homeobox KN domain Cation_ATPase_C PF00689.21 ORY43691.1 - 3.1e-44 150.9 9.8 4.7e-44 150.3 9.8 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 ORY43691.1 - 0.00044 20.1 0.8 0.00071 19.4 0.8 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORY43694.1 - 2.8e-36 124.8 1.8 2.8e-36 124.8 1.8 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 ORY43694.1 - 4.4e-12 45.9 0.1 8.7e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORY43694.1 - 9.7e-07 28.4 0.0 2.3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Ion_trans_2 PF07885.16 ORY43694.1 - 0.007 16.3 0.4 0.007 16.3 0.4 2.2 2 0 0 2 2 2 1 Ion channel Claudin_3 PF06653.11 ORY43694.1 - 0.092 12.7 3.3 0.17 11.8 0.1 2.3 2 0 0 2 2 2 0 Tight junction protein, Claudin-like Peptidase_S8 PF00082.22 ORY43695.1 - 3e-33 115.4 11.7 5e-33 114.6 11.7 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 ORY43695.1 - 5.8e-05 23.7 0.0 0.00012 22.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 GIT_SHD PF08518.11 ORY43697.1 - 5.5e-11 41.9 11.5 0.00042 19.9 0.2 5.5 5 0 0 5 5 5 5 Spa2 homology domain (SHD) of GIT DUF1192 PF06698.11 ORY43697.1 - 2.6 8.2 8.1 5.8 7.1 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) AA_kinase PF00696.28 ORY43698.1 - 1.5e-23 83.7 0.0 2e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Amino acid kinase family tRNA-synt_2b PF00587.25 ORY43699.1 - 6.8e-34 117.4 0.0 1.5e-33 116.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ORY43699.1 - 1.8e-18 66.5 0.1 3.7e-18 65.5 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 ORY43699.1 - 3.1e-13 49.5 0.0 5.7e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 ORY43699.1 - 5.2e-11 42.5 0.0 1.2e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF5110 PF17137.4 ORY43699.1 - 0.14 12.4 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) DUF3010 PF11215.8 ORY43699.1 - 0.16 12.3 0.9 3 8.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3010) Homeodomain PF00046.29 ORY43701.1 - 6.1e-08 32.4 2.0 1.2e-07 31.4 0.5 2.1 2 1 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 ORY43701.1 - 0.00019 21.3 0.3 0.00038 20.3 0.3 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.8 ORY43701.1 - 0.0032 16.9 0.3 0.007 15.8 0.3 1.6 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez ADH_zinc_N PF00107.26 ORY43703.1 - 0.0081 16.1 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY43703.1 - 0.093 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain WAP PF00095.21 ORY43704.1 - 3.9 7.9 13.6 1.7 9.1 2.0 2.6 1 1 1 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' Glyco_hydro_19 PF00182.19 ORY43706.1 - 3.8e-11 43.3 0.7 6.2e-11 42.6 0.4 1.4 1 1 0 1 1 1 1 Chitinase class I DEC-1_N PF04625.13 ORY43706.1 - 0.1 11.6 7.2 0.13 11.2 7.2 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region CDRT4 PF15213.6 ORY43707.1 - 0.053 14.1 2.0 0.1 13.2 2.0 1.6 1 1 0 1 1 1 0 CMT1A duplicated region transcript 4 protein Actino_peptide PF14408.6 ORY43707.1 - 0.11 12.7 0.6 1.5 9.0 0.1 2.3 2 0 0 2 2 2 0 Ribosomally synthesised peptide in actinomycetes LRRC37AB_C PF14914.6 ORY43708.1 - 0.083 12.8 0.2 0.12 12.3 0.2 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain CRC_subunit PF08624.10 ORY43709.1 - 3e-32 111.9 0.1 6e-32 110.9 0.1 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit PHD PF00628.29 ORY43709.1 - 6.6e-14 51.5 49.1 2.2e-11 43.5 9.7 5.1 4 1 1 5 5 5 3 PHD-finger Requiem_N PF14051.6 ORY43709.1 - 0.086 13.1 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 N-terminal domain of DPF2/REQ. 1-cysPrx_C PF10417.9 ORY43710.1 - 3.5e-09 36.4 0.0 6.9e-09 35.4 0.0 1.5 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA PF00578.21 ORY43710.1 - 6e-07 29.4 0.0 7.4e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY43710.1 - 0.034 13.9 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 Redoxin Mcl1_mid PF12341.8 ORY43711.1 - 1.7e-72 244.3 0.0 2.5e-72 243.7 0.0 1.2 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 ORY43711.1 - 0.018 15.3 0.0 1.2 9.5 0.0 3.1 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY43711.1 - 0.03 15.2 5.7 0.031 15.1 0.2 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat DNA_pol_alpha_N PF12254.8 ORY43711.1 - 0.65 10.1 10.1 0.082 13.0 4.8 2.1 1 1 1 2 2 2 0 DNA polymerase alpha subunit p180 N terminal DUF4515 PF14988.6 ORY43712.1 - 6.2e-08 32.7 21.7 6.2e-08 32.7 21.7 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4515) DUF2570 PF10828.8 ORY43713.1 - 0.071 12.9 0.6 0.075 12.9 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Iso_dh PF00180.20 ORY43714.1 - 5.8e-75 252.6 0.0 6.9e-75 252.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SH3_1 PF00018.28 ORY43715.1 - 1.1e-17 63.3 0.7 6e-08 32.2 0.0 2.5 2 0 0 2 2 2 2 SH3 domain FCH PF00611.23 ORY43715.1 - 6.2e-16 58.4 0.3 1.1e-14 54.4 0.2 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.22 ORY43715.1 - 2.3e-11 43.4 5.7 4.4e-11 42.5 5.7 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_9 PF14604.6 ORY43715.1 - 3.9e-11 42.6 0.2 2.4e-05 24.1 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 ORY43715.1 - 4.9e-10 38.9 0.0 2.4e-05 23.9 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 ORY43715.1 - 0.0039 17.4 0.7 0.4 11.0 0.5 2.3 2 0 0 2 2 2 1 Bacterial SH3 domain PHD PF00628.29 ORY43715.1 - 0.4 10.6 3.1 1.2 9.1 3.1 1.8 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.16 ORY43715.1 - 1.8 8.9 4.3 4.2 7.8 4.3 1.6 1 0 0 1 1 1 0 C1 domain UPF0052 PF01933.18 ORY43717.1 - 2e-37 129.0 0.0 4.5e-37 127.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Pkinase PF00069.25 ORY43718.1 - 1.9e-60 204.4 0.0 2.6e-60 204.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY43718.1 - 4.6e-32 111.3 0.0 6.3e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY43718.1 - 0.00012 21.5 0.0 0.00022 20.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY43718.1 - 0.0012 18.8 0.1 0.0064 16.5 0.0 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY43718.1 - 0.0062 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY43718.1 - 0.043 12.6 0.0 0.077 11.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase KA1 PF02149.19 ORY43718.1 - 0.043 13.6 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 Kinase associated domain 1 Choline_kinase PF01633.20 ORY43718.1 - 0.045 13.3 0.0 0.094 12.3 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 ORY43718.1 - 0.1 11.5 0.1 0.17 10.8 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 ORY43718.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 CxC6 PF18721.1 ORY43720.1 - 6.1e-13 48.8 9.7 1.1e-12 48.0 9.7 1.5 1 0 0 1 1 1 1 CxC6 like cysteine cluster associated with KDZ transposases DUF1465 PF07323.12 ORY43721.1 - 0.043 13.7 0.1 0.097 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) DUF761 PF05553.11 ORY43721.1 - 0.11 12.1 0.4 0.21 11.1 0.4 1.5 1 0 0 1 1 1 0 Cotton fibre expressed protein GILT PF03227.16 ORY43722.1 - 0.016 15.4 2.9 0.62 10.3 0.1 2.3 2 0 0 2 2 2 0 Gamma interferon inducible lysosomal thiol reductase (GILT) Defensin_4 PF07936.12 ORY43722.1 - 0.34 10.8 0.2 0.34 10.8 0.2 2.9 2 1 1 3 3 3 0 Potassium-channel blocking toxin I-EGF_1 PF18372.1 ORY43722.1 - 0.65 10.1 4.7 1.7 8.8 0.6 2.7 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 Atrophin-1 PF03154.15 ORY43723.1 - 0.8 7.9 16.9 1 7.6 16.9 1.0 1 0 0 1 1 1 0 Atrophin-1 family Polysacc_deac_1 PF01522.21 ORY43724.1 - 0.022 14.7 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide deacetylase Pentaxin PF00354.17 ORY43726.1 - 0.028 14.1 0.0 7.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Pentaxin family Polysacc_deac_1 PF01522.21 ORY43728.1 - 0.00018 21.4 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase HD_6 PF18019.1 ORY43728.1 - 0.078 13.1 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 HD domain Fapy_DNA_glyco PF01149.24 ORY43729.1 - 1e-27 97.0 0.0 2.5e-27 95.8 0.0 1.7 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 ORY43729.1 - 1.6e-23 82.5 0.0 2.7e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 ORY43729.1 - 0.00048 19.0 0.0 0.00077 18.3 0.0 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) CDC45 PF02724.14 ORY43729.1 - 0.032 12.5 0.6 0.035 12.4 0.6 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2 PF00096.26 ORY43730.1 - 3.9e-09 36.5 6.2 3.5e-05 24.0 1.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ORY43730.1 - 3.9e-07 29.9 4.4 0.0028 17.6 0.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ORY43730.1 - 9.5e-06 25.8 4.1 0.0069 16.8 0.8 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 ORY43730.1 - 0.0011 19.3 1.6 1.9 9.1 0.1 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY43730.1 - 0.0027 18.4 6.3 0.011 16.5 0.8 3.1 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2HE PF16278.5 ORY43730.1 - 0.0042 17.5 0.1 0.0042 17.5 0.1 2.0 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger ADK_lid PF05191.14 ORY43730.1 - 0.0091 16.0 1.1 0.021 14.8 1.1 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid PI3K_1B_p101 PF10486.9 ORY43730.1 - 0.036 11.8 5.8 0.047 11.5 5.8 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit zf-C2H2_jaz PF12171.8 ORY43730.1 - 0.041 14.2 3.2 0.17 12.2 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CDC45 PF02724.14 ORY43730.1 - 0.68 8.2 6.3 1.1 7.5 6.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Macoilin PF09726.9 ORY43730.1 - 2.3 6.7 6.6 3.5 6.1 6.6 1.3 1 0 0 1 1 1 0 Macoilin family BUD22 PF09073.10 ORY43730.1 - 3.1 7.1 13.7 4.1 6.6 13.7 1.2 1 0 0 1 1 1 0 BUD22 Apt1 PF10351.9 ORY43730.1 - 3.4 6.4 12.8 0.036 12.9 5.6 1.3 2 0 0 2 2 2 0 Golgi-body localisation protein domain Exo_endo_phos PF03372.23 ORY43732.1 - 5.8e-13 48.9 0.0 2e-12 47.1 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SR-25 PF10500.9 ORY43732.1 - 0.37 10.4 2.4 0.61 9.7 2.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein GTA_holin_3TM PF11351.8 ORY43733.1 - 0.58 10.7 2.7 0.67 10.5 2.7 1.2 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release PCRF PF03462.18 ORY43734.1 - 2e-42 145.3 0.2 2.4e-42 145.0 0.2 1.1 1 0 0 1 1 1 1 PCRF domain Syntaxin-6_N PF09177.11 ORY43734.1 - 0.1 13.2 0.5 3.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal ABC_tran_CTD PF16326.5 ORY43734.1 - 0.24 11.7 2.9 2.4 8.5 2.9 2.2 1 1 0 1 1 1 0 ABC transporter C-terminal domain MFS_1 PF07690.16 ORY43735.1 - 3.4e-12 45.9 31.6 7.1e-08 31.8 28.9 3.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 ORY43735.1 - 1.8e-11 44.0 14.1 2.3e-10 40.4 13.0 2.9 2 1 0 2 2 2 1 Nodulin-like MFS_1 PF07690.16 ORY43738.1 - 3.5e-22 78.8 36.8 5.4e-22 78.2 36.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.13 ORY43738.1 - 1.7e-15 57.2 16.3 1.7e-15 57.2 16.3 1.9 2 0 0 2 2 2 1 Nodulin-like PIRT PF15099.6 ORY43738.1 - 0.019 14.5 0.2 0.019 14.5 0.2 2.3 2 1 1 3 3 3 0 Phosphoinositide-interacting protein family MFS_MOT1 PF16983.5 ORY43738.1 - 0.97 9.9 11.1 1.8 9.0 7.5 3.0 1 1 1 2 2 2 0 Molybdate transporter of MFS superfamily Lipocalin_5 PF13924.6 ORY43739.1 - 0.025 14.4 0.0 0.04 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipocalin-like domain ICEA PF05315.11 ORY43739.1 - 0.032 13.7 1.0 0.048 13.1 1.0 1.2 1 0 0 1 1 1 0 ICEA Protein MMR_HSR1_Xtn PF16897.5 ORY43741.1 - 1.7e-33 114.8 1.4 2.7e-33 114.2 1.4 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 ORY43741.1 - 3.4e-18 65.4 0.0 7.2e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 ORY43741.1 - 2.4e-12 47.0 0.2 2.4e-10 40.5 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY43741.1 - 2.1e-05 24.1 0.1 0.0044 16.6 0.1 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORY43741.1 - 0.0022 18.1 0.2 0.56 10.3 0.0 2.4 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 ORY43741.1 - 0.069 12.1 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Rhodanese PF00581.20 ORY43742.1 - 6.5e-05 23.4 0.2 0.0002 21.8 0.2 1.8 1 1 0 1 1 1 1 Rhodanese-like domain PI-PLC-X PF00388.19 ORY43743.1 - 4.5e-51 172.2 0.0 3.7e-50 169.3 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PH_12 PF16457.5 ORY43743.1 - 6.7e-07 29.9 0.0 1.9e-06 28.5 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain EF-hand_like PF09279.11 ORY43743.1 - 0.00011 22.6 0.0 0.00025 21.5 0.0 1.6 1 1 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like Hemocyanin_C PF03723.14 ORY43743.1 - 0.086 12.2 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 Hemocyanin, ig-like domain PH_16 PF17838.1 ORY43743.1 - 0.11 12.4 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 PH domain PPTA PF01239.22 ORY43743.1 - 0.22 11.3 1.2 21 5.0 0.1 2.8 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat PI-PLC-Y PF00387.19 ORY43744.1 - 0.00012 22.4 0.0 0.00015 22.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 ORY43745.1 - 1.2e-11 44.8 0.0 1.5e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 C2 domain zf-PARP PF00645.18 ORY43746.1 - 9e-05 23.3 1.5 0.00046 21.0 0.1 2.4 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-PARP PF00645.18 ORY43747.1 - 1.5e-09 38.6 1.0 2.1e-09 38.1 0.0 1.8 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf_C2HC_14 PF18574.1 ORY43747.1 - 0.043 13.6 1.5 2.4 8.0 0.1 2.3 2 0 0 2 2 2 0 C2HC Zing finger domain Fer4_10 PF13237.6 ORY43747.1 - 0.43 10.7 3.4 6.1 7.0 3.1 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain GAGA_bind PF06217.12 ORY43749.1 - 0.86 9.8 15.9 1.1 9.5 15.9 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family GM_CSF PF01109.17 ORY43752.1 - 0.14 12.4 1.2 17 5.6 0.1 2.7 1 1 2 3 3 3 0 Granulocyte-macrophage colony-stimulating factor CD34_antigen PF06365.12 ORY43753.1 - 0.0014 18.3 0.0 0.0032 17.1 0.0 1.5 1 0 0 1 1 1 1 CD34/Podocalyxin family Adeno_E3_CR2 PF02439.15 ORY43753.1 - 0.0019 17.9 0.6 0.0019 17.9 0.6 2.1 2 0 0 2 2 2 1 Adenovirus E3 region protein CR2 FAM163 PF15069.6 ORY43753.1 - 0.026 15.0 0.0 0.046 14.2 0.0 1.3 1 0 0 1 1 1 0 FAM163 family CD99L2 PF12301.8 ORY43753.1 - 0.066 13.5 0.3 0.14 12.5 0.3 1.5 1 0 0 1 1 1 0 CD99 antigen like protein 2 SKG6 PF08693.10 ORY43753.1 - 0.067 12.6 3.1 0.056 12.9 1.4 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 ORY43753.1 - 0.069 14.0 0.0 0.12 13.3 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DAG1 PF05454.11 ORY43753.1 - 0.069 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) VSP PF03302.13 ORY43753.1 - 0.74 8.6 6.0 0.98 8.2 6.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Suf PF05843.14 ORY43754.1 - 0.96 9.4 8.7 1.2 9.0 8.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RIO1 PF01163.22 ORY43755.1 - 1.9e-56 190.6 5.2 1.9e-56 190.6 5.2 2.6 2 1 0 2 2 2 1 RIO1 family Cwf_Cwc_15 PF04889.12 ORY43755.1 - 0.0015 18.3 13.3 0.0015 18.3 13.3 2.0 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein CENP-N PF05238.13 ORY43755.1 - 0.019 14.3 3.8 0.041 13.2 3.8 1.5 1 0 0 1 1 1 0 Kinetochore protein CHL4 like SH3_11 PF18103.1 ORY43755.1 - 0.033 14.3 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 Retroviral integrase C-terminal SH3 domain Nop14 PF04147.12 ORY43755.1 - 0.042 12.1 15.9 0.07 11.3 15.9 1.3 1 0 0 1 1 1 0 Nop14-like family Choline_kinase PF01633.20 ORY43755.1 - 0.044 13.4 0.9 0.11 12.1 0.9 1.8 1 1 0 1 1 1 0 Choline/ethanolamine kinase CDC45 PF02724.14 ORY43755.1 - 0.47 8.7 19.3 0.035 12.4 14.6 1.5 2 0 0 2 2 2 0 CDC45-like protein Sigma70_ner PF04546.13 ORY43755.1 - 1.5 8.7 18.7 0.061 13.2 12.9 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Pkinase PF00069.25 ORY43755.1 - 4.7 6.5 10.0 0.033 13.6 0.5 2.2 3 1 0 3 3 3 0 Protein kinase domain CENP-B_dimeris PF09026.10 ORY43755.1 - 5.2 7.5 18.0 14 6.1 18.0 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FAM176 PF14851.6 ORY43755.1 - 5.7 6.6 11.2 3.2 7.4 7.2 2.4 2 0 0 2 2 2 0 FAM176 family DNA_pol_phi PF04931.13 ORY43755.1 - 7.6 4.5 24.2 14 3.7 24.2 1.4 1 0 0 1 1 1 0 DNA polymerase phi PTPRCAP PF15713.5 ORY43755.1 - 8.4 6.7 16.8 21 5.4 16.8 1.7 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated dCMP_cyt_deam_1 PF00383.23 ORY43757.1 - 9.4e-08 31.9 0.1 1.5e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY43757.1 - 0.00015 21.5 0.1 0.00018 21.2 0.1 1.2 1 0 0 1 1 1 1 MafB19-like deaminase DUF2076 PF09849.9 ORY43758.1 - 0.087 12.9 24.1 0.38 10.8 14.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Pex14_N PF04695.13 ORY43758.1 - 0.25 12.0 23.3 1.8 9.2 2.7 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3371 PF11851.8 ORY43758.1 - 0.79 10.8 17.9 2 9.5 2.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) TFIIA PF03153.13 ORY43758.1 - 1.4 8.8 42.1 0.23 11.4 4.5 2.8 2 1 1 3 3 3 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 ORY43758.1 - 3.4 7.2 45.1 0.43 10.2 20.8 2.3 2 0 0 2 2 2 0 Spt20 family Transglycosylas PF06737.14 ORY43759.1 - 0.0089 16.7 6.6 3.8 8.2 0.2 3.8 4 0 0 4 4 4 2 Transglycosylase-like domain YkuI_C PF10388.9 ORY43759.1 - 0.043 13.6 0.1 2.4 8.0 0.0 2.8 3 0 0 3 3 3 0 EAL-domain associated signalling protein domain DUF1811 PF08838.10 ORY43759.1 - 0.18 12.0 0.0 39 4.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1811) Epimerase PF01370.21 ORY43761.1 - 8.3e-31 107.3 0.0 1.1e-30 106.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY43761.1 - 7e-10 38.8 0.0 2.2e-05 24.0 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ORY43761.1 - 8.4e-06 25.0 0.0 1.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glycos_transf_2 PF00535.26 ORY43761.1 - 0.00022 21.1 0.0 0.00041 20.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 NAD_binding_10 PF13460.6 ORY43761.1 - 0.002 18.0 0.0 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 ORY43761.1 - 0.076 12.2 0.0 3.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein TFIIA PF03153.13 ORY43764.1 - 8.5 6.3 19.8 11 5.9 19.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DivIC PF04977.15 ORY43765.1 - 0.0014 18.3 0.3 0.015 15.0 0.2 2.1 2 0 0 2 2 2 1 Septum formation initiator PKcGMP_CC PF16808.5 ORY43765.1 - 0.0022 17.8 6.3 0.23 11.3 2.4 3.0 2 1 1 3 3 3 1 Coiled-coil N-terminus of cGMP-dependent protein kinase TMF_TATA_bd PF12325.8 ORY43765.1 - 0.003 17.8 2.4 0.0058 16.8 2.4 1.6 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 ORY43765.1 - 0.0054 16.7 4.6 0.008 16.2 3.4 1.8 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding GOLGA2L5 PF15070.6 ORY43765.1 - 0.006 15.3 0.2 0.0065 15.2 0.2 1.0 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 TSNAXIP1_N PF15739.5 ORY43765.1 - 0.0078 16.6 0.2 0.01 16.2 0.2 1.1 1 0 0 1 1 1 1 Translin-associated factor X-interacting N-terminus DUF4763 PF15960.5 ORY43765.1 - 0.0099 15.2 0.1 0.011 15.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) Dynactin_p22 PF07426.11 ORY43765.1 - 0.01 15.7 0.3 0.011 15.6 0.3 1.1 1 0 0 1 1 1 0 Dynactin subunit p22 CCDC92 PF14916.6 ORY43765.1 - 0.013 15.2 0.3 0.023 14.5 0.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Sec2p PF06428.11 ORY43765.1 - 0.014 15.3 0.2 0.66 10.0 0.0 2.2 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p Angiomotin_C PF12240.8 ORY43765.1 - 0.02 14.5 0.3 0.28 10.7 0.3 1.9 2 0 0 2 2 2 0 Angiomotin C terminal ATG16 PF08614.11 ORY43765.1 - 0.032 14.5 1.7 0.043 14.0 1.7 1.4 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) TBCA PF02970.16 ORY43765.1 - 0.032 14.5 1.6 0.12 12.8 1.1 1.8 1 1 1 2 2 2 0 Tubulin binding cofactor A HALZ PF02183.18 ORY43765.1 - 0.042 14.1 1.4 1.2 9.4 0.1 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Csm1_N PF18504.1 ORY43765.1 - 0.071 13.5 2.1 0.95 9.8 1.3 2.2 1 1 1 2 2 2 0 Csm1 N-terminal domain FlaC_arch PF05377.11 ORY43765.1 - 0.078 13.4 0.8 0.34 11.3 0.5 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) M PF02370.16 ORY43765.1 - 0.47 11.2 6.6 18 6.3 0.1 2.5 2 0 0 2 2 2 0 M protein repeat RRM_1 PF00076.22 ORY43766.1 - 2.6e-29 100.8 0.8 7.7e-16 57.7 0.0 2.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY43766.1 - 7.9e-05 22.4 0.0 0.0036 17.1 0.0 2.2 2 0 0 2 2 2 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 ORY43766.1 - 0.00033 21.0 0.8 2.4 8.3 0.0 3.3 2 1 1 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 ORY43766.1 - 0.00067 19.2 0.0 0.65 9.6 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY43766.1 - 0.0064 16.5 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.11 ORY43766.1 - 0.03 14.2 0.0 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) RRM_Rrp7 PF17799.1 ORY43766.1 - 0.2 11.5 0.2 1.2 8.9 0.0 2.2 2 1 1 3 3 3 0 Rrp7 RRM-like N-terminal domain Snf7 PF03357.21 ORY43767.1 - 8.1e-42 142.7 22.0 1.1e-41 142.4 22.0 1.1 1 0 0 1 1 1 1 Snf7 HAP1_N PF04849.13 ORY43767.1 - 0.027 13.7 6.4 0.041 13.1 6.4 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region YlqD PF11068.8 ORY43767.1 - 0.065 13.6 10.2 1.9 8.8 10.2 2.2 1 1 0 1 1 1 0 YlqD protein Ist1 PF03398.14 ORY43767.1 - 0.11 12.4 7.1 0.14 12.0 7.1 1.2 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DUF2570 PF10828.8 ORY43767.1 - 0.13 12.1 0.2 0.13 12.1 0.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2570) OKR_DC_1_C PF03711.15 ORY43767.1 - 0.32 11.3 2.4 0.31 11.3 0.5 1.9 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, C-terminal domain DUF1002 PF06207.11 ORY43767.1 - 2.1 7.8 9.2 0.25 10.8 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1002) Cep57_MT_bd PF06657.13 ORY43767.1 - 4.9 7.7 9.2 0.88 10.1 2.2 2.6 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 E1-E2_ATPase PF00122.20 ORY43768.1 - 6.8e-34 117.0 14.2 2.4e-32 111.9 8.9 3.3 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORY43768.1 - 1.2e-24 87.8 0.9 2.2e-20 73.8 0.3 3.0 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 ORY43768.1 - 5.1e-19 68.7 4.7 7.3e-18 64.9 0.8 2.6 2 0 0 2 2 2 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORY43768.1 - 2.4e-13 50.0 0.0 5.1e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY43768.1 - 8.4e-06 25.7 1.9 0.0016 18.2 0.5 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY43768.1 - 0.011 16.2 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase BatA PF07584.11 ORY43768.1 - 2 8.9 4.3 6 7.3 0.1 3.4 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal WD40 PF00400.32 ORY43769.1 - 2.1e-34 117.0 12.5 4.3e-06 27.4 0.1 7.2 6 1 1 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY43769.1 - 0.00048 20.4 0.1 0.26 11.6 0.0 3.6 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY43769.1 - 0.0023 16.7 1.4 0.08 11.6 1.1 3.1 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 ORY43769.1 - 0.0047 15.7 0.1 0.068 11.9 0.1 2.4 1 1 0 2 2 2 1 Nup133 N terminal like DUF5018 PF16410.5 ORY43769.1 - 0.013 14.2 0.2 0.037 12.7 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5018) WD40_like PF17005.5 ORY43769.1 - 0.053 12.8 0.0 0.11 11.8 0.0 1.6 1 1 0 1 1 1 0 WD40-like domain DRY_EERY PF09750.9 ORY43771.1 - 1.2e-13 51.5 1.2 2.9e-13 50.3 0.0 2.1 2 0 0 2 2 2 1 Alternative splicing regulator Peptidase_S49_N PF08496.10 ORY43771.1 - 0.045 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ribonuc_red_sm PF00268.21 ORY43772.1 - 5.6e-113 377.0 1.4 8.6e-113 376.4 1.4 1.3 1 1 0 1 1 1 1 Ribonucleotide reductase, small chain G-alpha PF00503.20 ORY43773.1 - 2.4e-91 306.6 3.9 8.6e-91 304.7 3.9 1.7 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY43773.1 - 6.6e-14 51.7 2.2 1.3e-10 41.0 0.1 3.1 3 0 0 3 3 3 2 ADP-ribosylation factor family Roc PF08477.13 ORY43773.1 - 9.6e-05 22.6 0.1 0.23 11.7 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 ORY43773.1 - 0.00054 19.5 0.3 0.18 11.3 0.1 2.6 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORY43773.1 - 0.047 13.0 2.9 0.31 10.4 0.1 2.6 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_25 PF13481.6 ORY43773.1 - 0.2 11.2 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Tom22 PF04281.13 ORY43774.1 - 6.2e-30 103.8 0.6 7.9e-30 103.5 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DctM PF06808.12 ORY43774.1 - 0.029 13.2 0.1 0.035 12.9 0.1 1.0 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporter, DctM component Pox_RNA_Pol_19 PF05320.12 ORY43774.1 - 0.069 13.1 1.2 0.11 12.5 1.2 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit IKKbetaNEMObind PF12179.8 ORY43775.1 - 0.24 11.5 1.0 3 7.9 0.1 2.7 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain DUF5601 PF18151.1 ORY43777.1 - 0.016 15.5 0.7 1.1 9.6 0.2 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5601) Prominin PF05478.11 ORY43777.1 - 8.3 4.2 14.5 6.8 4.5 12.4 1.7 1 1 0 1 1 1 0 Prominin HTH_29 PF13551.6 ORY43779.1 - 7.2e-07 29.1 0.1 1.2e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 ORY43779.1 - 7.4e-06 25.6 0.1 1.4e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain Terminase_5 PF06056.12 ORY43779.1 - 0.0094 15.8 0.1 0.016 15.1 0.1 1.3 1 0 0 1 1 1 1 Putative ATPase subunit of terminase (gpP-like) HTH_28 PF13518.6 ORY43779.1 - 0.0094 16.1 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Strumpellin PF10266.9 ORY43779.1 - 0.033 11.9 0.0 0.041 11.6 0.0 1.1 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin DUF4817 PF16087.5 ORY43779.1 - 0.058 13.2 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) DUF2428 PF10350.9 ORY43781.1 - 2.1e-55 188.0 0.5 1.7e-54 185.0 0.0 2.7 3 0 0 3 3 3 1 Putative death-receptor fusion protein (DUF2428) HEAT_2 PF13646.6 ORY43781.1 - 0.00073 19.9 0.4 3.5 8.1 0.0 4.7 6 0 0 6 6 6 2 HEAT repeats HEAT PF02985.22 ORY43781.1 - 0.006 16.7 6.5 12 6.5 0.1 7.0 8 0 0 8 8 8 2 HEAT repeat HSP70 PF00012.20 ORY43782.1 - 1.1e-143 479.7 4.0 3.7e-143 477.9 1.2 2.4 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 ORY43782.1 - 9.6e-07 27.9 0.0 2e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DUF775 PF05603.12 ORY43783.1 - 4e-55 186.4 0.0 7.3e-55 185.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF775) PAP2 PF01569.21 ORY43783.1 - 1.8e-18 66.7 3.1 1.8e-18 66.7 3.1 2.5 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 ORY43783.1 - 4.3e-10 39.6 2.8 1.1e-09 38.3 2.8 1.7 1 0 0 1 1 1 1 PAP2 superfamily Fz PF01392.22 ORY43784.1 - 0.00021 21.9 3.9 0.00048 20.7 3.9 1.6 1 0 0 1 1 1 1 Fz domain 7tm_1 PF00001.21 ORY43784.1 - 0.001 18.5 0.4 0.0018 17.6 0.4 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Frizzled PF01534.17 ORY43784.1 - 0.0022 17.1 11.4 0.053 12.6 5.0 2.3 2 0 0 2 2 2 2 Frizzled/Smoothened family membrane region DUF4710 PF15828.5 ORY43784.1 - 0.0064 16.6 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4710) E1-E2_ATPase PF00122.20 ORY43784.1 - 0.14 11.6 1.4 1.5 8.3 0.1 2.4 2 0 0 2 2 2 0 E1-E2 ATPase HXXEE PF13787.6 ORY43784.1 - 0.15 12.9 0.3 0.15 12.9 0.3 3.2 2 1 1 3 3 3 0 Protein of unknown function with HXXEE motif DNA_pol_delta_4 PF04081.13 ORY43785.1 - 9.4e-22 77.8 1.2 1.5e-21 77.1 1.2 1.4 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 SOBP PF15279.6 ORY43785.1 - 0.014 16.1 3.9 0.014 16.0 3.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Atg14 PF10186.9 ORY43786.1 - 2.2e-07 30.3 3.2 2.2e-07 30.3 3.2 2.3 2 1 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 KASH_CCD PF14662.6 ORY43786.1 - 0.0087 15.9 0.7 0.0087 15.9 0.7 2.3 3 1 0 3 3 3 1 Coiled-coil region of CCDC155 or KASH DUF4778 PF16008.5 ORY43786.1 - 0.03 14.4 1.8 0.047 13.7 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4778) MAD PF05557.13 ORY43787.1 - 3.8e-49 167.7 64.5 6.3e-48 163.6 64.5 2.0 1 1 0 1 1 1 1 Mitotic checkpoint protein DUF4250 PF14056.6 ORY43787.1 - 0.45 10.5 6.4 3.5 7.6 0.4 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) BRI3BP PF14965.6 ORY43787.1 - 5.2 6.5 10.9 7.8 6.0 0.2 3.9 4 0 0 4 4 4 0 Negative regulator of p53/TP53 DASH_Hsk3 PF08227.11 ORY43787.1 - 6.1 7.3 11.9 51 4.3 1.8 5.1 5 0 0 5 5 5 0 DASH complex subunit Hsk3 like 2-Hacid_dh_C PF02826.19 ORY43788.1 - 8e-39 132.8 0.0 2.6e-37 127.9 0.0 2.1 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 ORY43788.1 - 0.0015 18.7 0.3 0.0058 16.8 0.3 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 ORY43788.1 - 0.049 13.9 0.1 0.1 12.8 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ThiF PF00899.21 ORY43788.1 - 0.059 12.7 0.0 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 ThiF family F420_oxidored PF03807.17 ORY43788.1 - 0.14 12.8 0.1 0.27 11.8 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GCV_T PF01571.21 ORY43789.1 - 3.4e-14 52.8 0.0 5e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Myb_DNA-binding PF00249.31 ORY43790.1 - 2.3e-05 24.5 0.1 0.00015 21.9 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY43790.1 - 0.09 13.0 0.0 0.83 10.0 0.0 2.2 2 0 0 2 2 2 0 Myb-like DNA-binding domain MFS_1 PF07690.16 ORY43791.1 - 0.00024 20.1 26.2 0.039 12.9 2.9 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.13 ORY43791.1 - 0.0062 16.0 0.6 0.0062 16.0 0.6 2.9 2 2 1 3 3 3 1 Nodulin-like MOZ_SAS PF01853.18 ORY43792.1 - 2e-67 226.3 6.2 6e-47 159.6 0.7 2.6 2 1 1 3 3 3 2 MOZ/SAS family zf-MYST PF17772.1 ORY43792.1 - 4.9e-13 48.5 0.1 4.9e-13 48.5 0.1 2.2 2 0 0 2 2 2 1 MYST family zinc finger domain zf-MYND PF01753.18 ORY43793.1 - 1.8e-11 44.0 12.7 1.8e-11 44.0 12.7 3.3 2 1 0 2 2 2 1 MYND finger zf-C3HC4 PF00097.25 ORY43793.1 - 2.1e-08 33.9 2.2 2.1e-08 33.9 2.2 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY43793.1 - 2e-07 31.2 5.8 2e-07 31.2 5.8 2.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY43793.1 - 2.1e-07 30.8 5.4 3.7e-07 30.1 3.6 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORY43793.1 - 4.3e-07 29.7 6.7 4.3e-07 29.7 6.7 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY43793.1 - 2.1e-06 27.5 2.3 2.1e-06 27.5 2.3 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY43793.1 - 2.7e-06 27.2 3.2 2.7e-06 27.2 3.2 2.6 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORY43793.1 - 2.9e-05 24.1 6.2 2.9e-05 24.1 6.2 3.0 2 2 0 2 2 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ORY43793.1 - 3.7e-05 23.5 5.7 3.7e-05 23.5 5.7 3.0 2 2 0 2 2 1 1 Prokaryotic RING finger family 4 TPR_14 PF13428.6 ORY43793.1 - 0.00043 20.9 0.3 0.022 15.5 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY43793.1 - 0.00086 19.8 0.2 0.042 14.3 0.4 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY43793.1 - 0.0015 18.7 1.4 0.022 15.0 0.3 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 ORY43793.1 - 0.0027 18.0 0.6 2.9 8.2 0.0 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat zf-RING_11 PF17123.5 ORY43793.1 - 0.0034 17.1 5.3 0.0034 17.1 5.3 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_6 PF14835.6 ORY43793.1 - 0.012 15.5 0.7 0.012 15.5 0.7 2.8 3 0 0 3 3 3 0 zf-RING of BARD1-type protein TPR_2 PF07719.17 ORY43793.1 - 0.022 14.8 2.2 5.4 7.4 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY43793.1 - 0.065 12.6 0.1 0.12 11.7 0.0 1.5 2 0 0 2 2 2 0 MalT-like TPR region Glyco_hydro_92 PF07971.12 ORY43793.1 - 0.2 10.6 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 zf-C2H2_jaz PF12171.8 ORY43794.1 - 6.5e-11 42.2 0.6 9.9e-11 41.6 0.6 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY43794.1 - 0.0015 18.9 0.1 0.0025 18.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 ORY43794.1 - 0.0079 16.5 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 ORY43794.1 - 0.022 15.6 0.2 0.038 14.8 0.2 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger DEP PF00610.21 ORY43795.1 - 1.2e-14 54.0 0.1 4e-14 52.4 0.0 1.9 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RGS PF00615.19 ORY43795.1 - 4.3e-12 46.4 0.9 6.3e-08 32.9 0.0 3.5 3 1 0 4 4 4 2 Regulator of G protein signaling domain RGS_DHEX PF18148.1 ORY43795.1 - 8.7e-11 41.8 1.1 1.7e-10 40.9 1.1 1.4 1 0 0 1 1 1 1 Regulator of G-protein signalling DHEX domain Clat_adaptor_s PF01217.20 ORY43796.1 - 6.1e-56 188.3 5.2 6.9e-56 188.1 5.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PCAF_N PF06466.11 ORY43796.1 - 0.045 13.3 0.3 0.054 13.1 0.3 1.1 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain TFIIA PF03153.13 ORY43797.1 - 1.9e-53 183.0 28.2 2.2e-39 136.7 18.7 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.12 ORY43797.1 - 1 9.0 20.4 0.19 11.5 11.8 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Ndc1_Nup PF09531.10 ORY43797.1 - 6.4 5.3 8.5 7.2 5.2 8.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ion_trans PF00520.31 ORY43798.1 - 1.7e-30 106.0 28.1 2.3e-30 105.6 28.1 1.1 1 0 0 1 1 1 1 Ion transport protein Renin_r PF07850.14 ORY43798.1 - 0.19 12.4 7.0 2.3 8.9 1.0 3.1 3 0 0 3 3 3 0 Renin receptor-like protein DUF4577 PF15145.6 ORY43798.1 - 0.24 11.5 1.6 0.65 10.0 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) OPT PF03169.15 ORY43799.1 - 2.4e-80 270.9 24.4 3.3e-80 270.5 24.4 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ECH_1 PF00378.20 ORY43801.1 - 2.1e-41 141.9 0.0 2.5e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY43801.1 - 1.1e-18 67.9 0.0 1.2e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Carboxyl_trans PF01039.22 ORY43801.1 - 0.044 12.4 0.1 0.063 11.9 0.1 1.1 1 0 0 1 1 1 0 Carboxyl transferase domain Band_7 PF01145.25 ORY43802.1 - 1.7e-33 116.1 3.6 3.7e-33 115.0 3.6 1.6 1 1 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 ORY43802.1 - 1.4e-23 82.7 4.4 1.3e-22 79.6 1.9 2.7 2 0 0 2 2 2 1 C-terminal region of band_7 Band_7_1 PF13421.6 ORY43802.1 - 0.037 13.7 1.0 0.072 12.8 0.1 2.0 2 1 0 2 2 2 0 SPFH domain-Band 7 family RLL PF10036.9 ORY43802.1 - 0.043 13.7 3.2 0.079 12.8 3.2 1.3 1 1 0 1 1 1 0 RNA transcription, translation and transport factor protein RecX PF02631.16 ORY43802.1 - 0.064 13.7 0.6 0.13 12.7 0.2 1.7 1 1 1 2 2 2 0 RecX family Lactamase_B_2 PF12706.7 ORY43803.1 - 1e-23 83.9 2.0 1.3e-14 54.2 0.0 2.6 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORY43803.1 - 5.4e-11 42.6 0.2 1.6e-10 41.1 0.1 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain zf-MYND PF01753.18 ORY43804.1 - 1.5e-06 28.2 19.2 1.5e-06 28.2 19.2 4.2 2 2 1 3 3 3 1 MYND finger Stc1 PF12898.7 ORY43804.1 - 0.035 14.6 16.9 0.035 14.6 16.9 2.9 2 2 0 2 2 2 0 Stc1 domain MatE PF01554.18 ORY43805.1 - 3.1e-53 179.7 21.7 7.7e-28 97.2 7.8 2.5 2 0 0 2 2 2 2 MatE Peptidase_M1 PF01433.20 ORY43806.1 - 2.3e-46 158.1 0.0 5.1e-46 157.0 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 ORY43806.1 - 1.3e-38 131.5 0.2 2.7e-38 130.5 0.2 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 ORY43806.1 - 7.6e-21 75.1 0.4 1.3e-20 74.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Peptidase_M48 PF01435.18 ORY43806.1 - 0.061 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M48 Peptidase_MA_2 PF13485.6 ORY43806.1 - 0.15 11.7 0.2 0.68 9.6 0.2 1.9 1 1 0 1 1 1 0 Peptidase MA superfamily Peptidase_M61 PF05299.12 ORY43806.1 - 0.17 12.3 0.5 2.4 8.6 0.5 2.4 1 1 0 1 1 1 0 M61 glycyl aminopeptidase F-box PF00646.33 ORY43807.1 - 9.9e-06 25.3 0.9 1.7e-05 24.5 0.9 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY43807.1 - 5.6e-05 23.0 0.3 9.5e-05 22.2 0.3 1.3 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORY43807.1 - 0.00042 20.2 0.1 0.00078 19.3 0.0 1.6 2 0 0 2 2 2 1 F-box Vps39_2 PF10367.9 ORY43809.1 - 6e-14 52.4 0.0 5.1e-12 46.2 0.0 3.2 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 ORY43809.1 - 7.6e-12 45.5 0.6 2.3e-11 43.9 0.6 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 ORY43809.1 - 0.00012 21.7 0.0 0.00039 20.1 0.0 1.8 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 ORY43809.1 - 0.00019 21.3 6.9 0.62 9.9 2.7 3.6 3 0 0 3 3 3 2 Region in Clathrin and VPS DUF4460 PF14687.6 ORY43809.1 - 0.13 12.3 0.2 0.44 10.6 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) DNA_pol_A_exo1 PF01612.20 ORY43811.1 - 2.1e-08 34.1 0.0 4.7e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease Leo1 PF04004.13 ORY43812.1 - 2e-40 138.3 0.2 2e-40 138.3 0.2 2.0 2 1 0 2 2 2 1 Leo1-like protein BUD22 PF09073.10 ORY43812.1 - 0.11 11.8 19.6 0.2 11.0 19.6 1.4 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 ORY43812.1 - 0.16 10.7 3.1 0.22 10.3 3.1 1.2 1 0 0 1 1 1 0 Presenilin TFIIF_alpha PF05793.12 ORY43812.1 - 3.9 5.9 16.4 6.9 5.1 16.4 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RasGEF PF00617.19 ORY43814.1 - 1e-43 149.6 0.0 8.4e-42 143.4 0.0 2.6 2 1 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 ORY43814.1 - 1.9e-20 73.0 0.6 4.6e-20 71.8 0.6 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif RBD PF02196.15 ORY43814.1 - 0.00026 21.0 0.0 0.0053 16.8 0.0 2.6 2 0 0 2 2 2 1 Raf-like Ras-binding domain CTX_RstB PF07459.11 ORY43814.1 - 0.0038 17.4 0.0 0.014 15.6 0.0 2.0 1 0 0 1 1 1 1 CTX phage RstB protein RD3 PF14473.6 ORY43814.1 - 0.0077 16.1 0.8 0.15 11.9 0.5 2.4 2 0 0 2 2 2 1 RD3 protein DOCK-C2 PF14429.6 ORY43815.1 - 0.022 14.6 0.0 0.059 13.2 0.0 1.7 2 0 0 2 2 2 0 C2 domain in Dock180 and Zizimin proteins Med26 PF08711.11 ORY43816.1 - 2.3e-12 46.7 0.8 8.4e-12 44.9 0.0 2.3 3 0 0 3 3 3 1 TFIIS helical bundle-like domain ParG PF09274.10 ORY43816.1 - 0.053 13.7 0.1 1.1 9.5 0.0 2.6 2 0 0 2 2 2 0 ParG GET2 PF08690.10 ORY43816.1 - 0.22 11.2 3.1 0.3 10.7 3.1 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 DUF4200 PF13863.6 ORY43816.1 - 0.44 11.0 6.8 1.2 9.5 6.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DUF2630 PF10944.8 ORY43816.1 - 0.89 10.1 4.1 0.4 11.2 0.5 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2630) NDK PF00334.19 ORY43818.1 - 3.5e-15 56.2 0.0 4.6e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Dpy-30 PF05186.13 ORY43818.1 - 1.4e-12 47.1 0.2 2.3e-12 46.4 0.2 1.3 1 0 0 1 1 1 1 Dpy-30 motif WD40 PF00400.32 ORY43819.1 - 8.7e-09 35.9 3.8 0.027 15.4 0.1 6.3 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY43819.1 - 5.7e-07 29.7 0.0 2.2 8.7 0.0 5.1 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain GUCT PF08152.12 ORY43819.1 - 0.12 12.7 0.0 8.6 6.7 0.0 2.8 1 1 1 2 2 2 0 GUCT (NUC152) domain JAB PF01398.21 ORY43820.1 - 7e-28 97.0 0.0 1.3e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 ORY43820.1 - 1.5e-12 47.9 0.5 2.5e-12 47.2 0.5 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 ORY43820.1 - 4.5e-06 26.4 0.0 6.8e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain GCP_C_terminal PF04130.13 ORY43822.1 - 1.1e-17 64.5 0.6 1.1e-17 64.5 0.6 3.8 3 1 0 3 3 3 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 ORY43822.1 - 4.1e-09 36.5 3.9 1e-08 35.2 3.9 1.8 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Oscp1 PF10188.9 ORY43822.1 - 0.028 14.5 3.8 8.8 6.4 0.0 3.8 3 0 0 3 3 3 0 Organic solute transport protein 1 ASC PF00858.24 ORY43823.1 - 0.0098 14.9 0.2 0.16 10.9 0.1 2.1 1 1 1 2 2 2 2 Amiloride-sensitive sodium channel DctQ PF04290.12 ORY43823.1 - 0.032 14.2 0.2 0.07 13.0 0.0 1.6 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Aquarius_N PF16399.5 ORY43824.1 - 4.7e-248 825.3 4.3 6.5e-248 824.9 4.3 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 ORY43824.1 - 1.4e-26 93.9 0.0 1.4e-25 90.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.6 ORY43824.1 - 1.3e-16 60.9 0.1 3.2e-13 49.7 0.0 3.8 2 1 0 3 3 3 2 AAA domain AAA_19 PF13245.6 ORY43824.1 - 5e-09 36.6 0.0 4e-08 33.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY43824.1 - 5.2e-08 32.8 0.1 0.00054 19.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 ORY43824.1 - 3.6e-05 23.8 0.0 0.0001 22.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 ORY43824.1 - 0.0003 20.4 0.2 0.0013 18.4 0.0 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA PF00004.29 ORY43824.1 - 0.012 16.0 0.0 0.077 13.4 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.6 ORY43824.1 - 0.021 14.7 0.1 0.049 13.5 0.1 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 ORY43824.1 - 0.025 15.0 0.0 0.095 13.1 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain DEAD PF00270.29 ORY43824.1 - 0.059 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase ATPase PF06745.13 ORY43824.1 - 0.069 12.5 0.0 0.2 10.9 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_27 PF13514.6 ORY43824.1 - 0.076 12.6 0.0 4.9 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 ORY43824.1 - 0.08 12.7 0.0 0.93 9.2 0.0 2.5 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ABC2_membrane PF01061.24 ORY43825.1 - 9.3e-38 129.7 19.8 9.3e-38 129.7 19.8 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 ORY43825.1 - 8.7e-26 91.1 0.1 1.4e-25 90.4 0.1 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 ORY43825.1 - 1.2e-05 25.3 0.1 2.2e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 ORY43825.1 - 0.00022 21.6 0.0 0.00038 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY43825.1 - 0.00084 19.6 0.0 0.0024 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 ORY43825.1 - 0.0015 18.6 0.2 0.003 17.6 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SMC_N PF02463.19 ORY43825.1 - 0.0049 16.3 0.0 0.011 15.2 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ORY43825.1 - 0.0053 16.6 0.3 6.2 6.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 ORY43825.1 - 0.0055 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORY43825.1 - 0.007 16.1 0.2 0.017 14.8 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_28 PF13521.6 ORY43825.1 - 0.011 16.0 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ORY43825.1 - 0.017 15.1 0.0 0.043 13.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain MeaB PF03308.16 ORY43825.1 - 0.023 13.7 0.6 0.036 13.0 0.2 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 ORY43825.1 - 0.025 14.3 0.2 0.045 13.5 0.2 1.3 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 ORY43825.1 - 0.052 12.8 0.0 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Glu_dehyd_C PF16912.5 ORY43825.1 - 0.06 12.8 0.0 0.098 12.1 0.0 1.2 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus RNA_helicase PF00910.22 ORY43825.1 - 0.069 13.5 0.0 0.23 11.9 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Dynamin_N PF00350.23 ORY43825.1 - 0.096 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Dynamin family T2SSE PF00437.20 ORY43825.1 - 0.099 11.7 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SAMP PF05924.11 ORY43825.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 SAMP Motif DUF87 PF01935.17 ORY43825.1 - 0.14 12.2 0.3 0.3 11.2 0.3 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_24 PF13479.6 ORY43825.1 - 0.14 11.8 0.1 0.31 10.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ORY43825.1 - 0.16 11.7 0.1 0.33 10.7 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 ORY43825.1 - 0.18 11.1 0.2 0.27 10.5 0.2 1.2 1 0 0 1 1 1 0 Zeta toxin ABC2_membrane_2 PF12679.7 ORY43825.1 - 0.92 8.7 9.5 0.27 10.5 5.0 2.0 1 1 0 2 2 2 0 ABC-2 family transporter protein Acyl-CoA_dh_1 PF00441.24 ORY43826.1 - 1.8e-41 141.9 0.4 2.8e-41 141.2 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY43826.1 - 9e-39 132.6 0.0 1.9e-38 131.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ORY43826.1 - 1.1e-24 86.5 0.0 2e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY43826.1 - 1.3e-12 48.1 0.1 2.2e-12 47.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain UBZ_FAAP20 PF15750.5 ORY43826.1 - 0.3 11.1 0.8 0.82 9.7 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger bZIP_1 PF00170.21 ORY43827.1 - 6.7e-06 26.1 4.6 1.2e-05 25.3 4.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY43827.1 - 1.9e-05 24.6 7.3 1.9e-05 24.6 7.3 2.5 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORY43827.1 - 0.0012 19.3 8.0 0.0012 19.3 8.0 1.5 2 0 0 2 2 2 1 bZIP Maf transcription factor MipZ PF09140.11 ORY43827.1 - 0.0072 15.6 1.8 0.0099 15.2 1.2 1.4 1 1 0 1 1 1 1 ATPase MipZ APG6_N PF17675.1 ORY43827.1 - 0.087 13.4 2.0 0.13 12.8 2.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Med21 PF11221.8 ORY43827.1 - 0.38 11.0 6.6 0.71 10.1 6.6 1.5 1 0 0 1 1 1 0 Subunit 21 of Mediator complex DivIC PF04977.15 ORY43827.1 - 0.4 10.5 3.3 0.9 9.3 3.3 1.5 1 0 0 1 1 1 0 Septum formation initiator ATG16 PF08614.11 ORY43827.1 - 1.7 8.8 12.1 2.8 8.1 12.0 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) rve PF00665.26 ORY43830.1 - 0.37 11.0 3.7 8.4e+02 0.2 0.0 6.9 3 2 5 10 10 10 0 Integrase core domain IL28A PF15177.6 ORY43832.1 - 0.053 13.4 0.1 0.084 12.7 0.1 1.3 1 0 0 1 1 1 0 Interleukin-28A DUF1415 PF07209.12 ORY43832.1 - 0.1 12.3 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1415) ORC4_C PF14629.6 ORY43834.1 - 5.5e-23 81.5 0.0 9.7e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 ORY43834.1 - 8.3e-11 42.6 0.0 4.8e-10 40.1 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY43834.1 - 4.1e-09 36.8 0.0 9.2e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 ORY43834.1 - 6.7e-07 29.8 0.0 1.5e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ORY43834.1 - 5.6e-06 26.0 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region DAP3 PF10236.9 ORY43834.1 - 0.00075 18.8 0.0 4.4 6.4 0.0 3.2 3 0 0 3 3 3 1 Mitochondrial ribosomal death-associated protein 3 ATPase_2 PF01637.18 ORY43834.1 - 0.0092 15.9 0.0 0.029 14.3 0.0 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 ORY43834.1 - 0.01 15.8 0.0 0.026 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 ORY43834.1 - 0.017 14.5 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein DUF815 PF05673.13 ORY43834.1 - 0.022 13.9 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Cas_CXXC_CXXC PF09706.10 ORY43834.1 - 0.13 12.5 0.3 0.34 11.2 0.2 1.8 2 0 0 2 2 1 0 CRISPR-associated protein (Cas_CXXC_CXXC) Mg_chelatase PF01078.21 ORY43834.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Hamartin PF04388.12 ORY43834.1 - 0.62 8.7 4.2 0.78 8.3 4.2 1.1 1 0 0 1 1 1 0 Hamartin protein Dicty_REP PF05086.12 ORY43834.1 - 1.3 6.9 6.3 1.7 6.5 6.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Xpo1 PF08389.12 ORY43835.1 - 1.3e-22 80.5 0.2 1.3e-22 80.5 0.2 2.9 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 ORY43835.1 - 1.8e-07 30.9 0.2 3.7e-06 26.8 0.0 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Abhydrolase_1 PF00561.20 ORY43836.1 - 2.5e-29 102.7 0.0 3e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY43836.1 - 5.6e-13 48.7 0.0 2.6e-12 46.5 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY43836.1 - 5.2e-08 33.8 0.1 7.5e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 ORY43836.1 - 0.0009 18.0 0.0 0.0017 17.1 0.0 1.4 1 0 0 1 1 1 1 Ndr family Peptidase_S28 PF05577.12 ORY43836.1 - 0.18 10.5 0.3 0.45 9.3 0.0 1.7 2 0 0 2 2 2 0 Serine carboxypeptidase S28 DUF1761 PF08570.10 ORY43837.1 - 5.2e-11 42.9 0.1 6.4e-11 42.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) F-box-like PF12937.7 ORY43838.1 - 5.9e-09 35.7 0.4 1.4e-08 34.5 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY43838.1 - 0.037 13.9 0.4 0.037 13.9 0.4 2.5 3 0 0 3 3 3 0 F-box domain SNF2_N PF00176.23 ORY43840.1 - 1.8e-57 194.6 0.2 2.4e-56 191.0 0.1 2.3 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY43840.1 - 1.9e-17 63.6 0.0 4.5e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY43840.1 - 2.7e-09 37.3 0.0 6.9e-09 35.9 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY43840.1 - 5.3e-06 26.3 0.0 1.3e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 ORY43840.1 - 0.0046 15.9 0.1 0.016 14.1 0.1 1.8 1 1 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 ERCC3_RAD25_C PF16203.5 ORY43840.1 - 0.017 14.3 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase SWI2_SNF2 PF18766.1 ORY43840.1 - 0.067 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Il2rg PF15874.5 ORY43841.1 - 8.3e-22 77.3 0.0 1.2e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Putative Interleukin 2 receptor, gamma chain UL11 PF11094.8 ORY43841.1 - 0.034 14.0 0.1 0.064 13.1 0.1 1.4 1 0 0 1 1 1 0 Membrane-associated tegument protein SUI1 PF01253.22 ORY43842.1 - 7.8e-22 77.6 0.2 1.3e-21 76.9 0.2 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 CTP_synth_N PF06418.14 ORY43843.1 - 8.2e-126 418.7 0.1 1.1e-125 418.3 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 ORY43843.1 - 6.4e-56 189.1 0.0 9.6e-56 188.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORY43843.1 - 0.0011 18.7 0.2 0.004 16.9 0.2 1.9 1 1 0 1 1 1 1 Peptidase C26 Syntaxin PF00804.25 ORY43844.1 - 2.6e-24 86.0 10.2 4.4e-24 85.3 10.2 1.3 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 ORY43844.1 - 2.6e-15 56.2 0.6 2.6e-15 56.2 0.6 2.4 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.9 ORY43844.1 - 0.0011 18.7 12.0 0.0017 18.1 11.7 1.6 1 1 0 1 1 1 1 Membrane fusion protein Use1 TMCO5 PF14992.6 ORY43844.1 - 0.0011 18.6 8.7 0.004 16.8 2.4 2.5 3 0 0 3 3 3 1 TMCO5 family LMBR1 PF04791.16 ORY43844.1 - 0.0033 16.4 4.2 0.0043 16.0 4.2 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein SKA1 PF07160.12 ORY43844.1 - 0.0069 16.3 5.7 0.0069 16.3 5.7 2.7 2 1 1 3 3 3 1 Spindle and kinetochore-associated protein 1 CENP-K PF11802.8 ORY43844.1 - 0.013 15.1 4.0 0.034 13.7 4.0 1.7 1 1 0 1 1 1 0 Centromere-associated protein K Syntaxin_2 PF14523.6 ORY43844.1 - 0.036 14.4 13.1 0.057 13.8 1.4 3.0 2 2 0 2 2 2 0 Syntaxin-like protein APG17 PF04108.12 ORY43844.1 - 0.038 13.1 11.2 0.34 10.0 4.6 2.3 1 1 1 2 2 2 0 Autophagy protein Apg17 MCPsignal PF00015.21 ORY43844.1 - 0.054 13.3 8.4 0.031 14.1 2.3 2.5 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain VitD-bind_III PF09164.10 ORY43844.1 - 0.069 13.1 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Vitamin D binding protein, domain III FapA PF03961.13 ORY43844.1 - 0.072 11.7 13.2 0.035 12.7 7.3 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A PCRF PF03462.18 ORY43844.1 - 0.1 12.5 11.0 0.041 13.7 2.9 2.4 2 1 0 2 2 2 0 PCRF domain Prominin PF05478.11 ORY43844.1 - 0.13 10.2 12.7 1.2 7.0 12.0 2.0 1 1 0 1 1 1 0 Prominin CrgA PF06781.12 ORY43844.1 - 0.15 12.1 1.0 0.58 10.3 1.0 2.0 1 0 0 1 1 1 0 Cell division protein CrgA Pox_EPC_I2-L1 PF12575.8 ORY43844.1 - 0.18 12.1 0.3 0.41 10.9 0.3 1.6 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 Laminin_II PF06009.12 ORY43844.1 - 0.18 11.8 11.3 0.31 11.0 4.1 2.7 2 0 0 2 2 2 0 Laminin Domain II Spectrin PF00435.21 ORY43844.1 - 0.2 12.2 12.2 1.1 9.7 0.2 2.8 2 1 1 3 3 3 0 Spectrin repeat YkyA PF10368.9 ORY43844.1 - 0.24 11.1 14.6 0.39 10.4 7.3 2.4 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Syntaxin-6_N PF09177.11 ORY43844.1 - 0.26 11.8 11.7 4.5 7.9 3.2 3.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF2951 PF11166.8 ORY43844.1 - 0.3 11.3 6.3 0.12 12.6 1.6 2.5 2 1 1 3 3 2 0 Protein of unknown function (DUF2951) TMPIT PF07851.13 ORY43844.1 - 0.34 10.1 9.3 0.66 9.2 1.5 2.3 2 0 0 2 2 2 0 TMPIT-like protein AIP3 PF03915.13 ORY43844.1 - 0.4 9.7 19.7 5.4 6.0 18.0 2.1 1 1 1 2 2 2 0 Actin interacting protein 3 DUF3720 PF12517.8 ORY43844.1 - 0.42 11.6 10.9 0.22 12.5 7.5 2.3 2 0 0 2 2 1 0 Protein of unknown function (DUF3720) EspB PF05802.11 ORY43844.1 - 0.67 9.9 20.8 0.036 14.1 5.3 2.5 1 1 1 2 2 2 0 Enterobacterial EspB protein RIFIN PF02009.16 ORY43844.1 - 0.72 9.7 13.9 0.11 12.3 7.4 2.1 1 1 1 2 2 2 0 Rifin DUF5344 PF17279.2 ORY43844.1 - 0.75 10.4 10.2 24 5.6 5.5 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5344) Med11 PF10280.9 ORY43844.1 - 0.82 10.1 18.9 1.2 9.6 2.4 3.7 1 1 2 3 3 3 0 Mediator complex protein ApoO PF09769.9 ORY43844.1 - 0.88 9.5 3.0 3.6 7.6 0.6 2.7 3 1 0 3 3 2 0 Apolipoprotein O ING PF12998.7 ORY43844.1 - 0.99 10.0 7.4 0.67 10.6 2.2 2.5 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding SKA2 PF16740.5 ORY43844.1 - 1.2 8.9 16.5 1.6 8.5 4.2 3.7 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 Tweety PF04906.13 ORY43844.1 - 1.3 7.6 6.9 0.29 9.8 1.9 2.0 2 0 0 2 2 2 0 Tweety Synaptobrevin PF00957.21 ORY43844.1 - 1.4 8.8 13.8 0.41 10.5 7.5 3.2 2 2 0 2 2 2 0 Synaptobrevin CK2S PF15011.6 ORY43844.1 - 1.4 8.8 11.4 0.19 11.6 6.1 2.1 2 2 0 2 2 2 0 Casein Kinase 2 substrate DUF745 PF05335.13 ORY43844.1 - 1.9 8.2 17.0 0.24 11.1 7.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF745) NPV_P10 PF05531.12 ORY43844.1 - 1.9 9.0 9.8 11 6.5 2.6 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein YtxH PF12732.7 ORY43844.1 - 2.5 8.7 6.4 23 5.6 0.3 3.0 2 1 0 2 2 2 0 YtxH-like protein DUF2408 PF10303.9 ORY43844.1 - 3.8 8.1 13.7 15 6.2 1.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DegS PF05384.11 ORY43844.1 - 4.9 6.6 13.6 0.56 9.7 4.6 2.9 2 1 0 2 2 2 0 Sensor protein DegS DUF16 PF01519.16 ORY43844.1 - 6.6 7.3 12.3 1.4 9.5 6.5 2.4 3 0 0 3 3 2 0 Protein of unknown function DUF16 PBP1_TM PF14812.6 ORY43844.1 - 6.6 7.2 8.1 2.9 8.3 0.1 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HisKA_3 PF07730.13 ORY43844.1 - 6.9 7.3 7.3 3.5 8.2 0.9 3.2 2 2 0 2 2 2 0 Histidine kinase DUF883 PF05957.13 ORY43844.1 - 7 7.3 11.0 0.93 10.1 0.4 3.4 3 1 0 3 3 2 0 Bacterial protein of unknown function (DUF883) Carn_acyltransf PF00755.20 ORY43845.1 - 7.6e-181 602.7 0.0 8.5e-181 602.5 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Ceramidase PF05875.12 ORY43846.1 - 4.2e-71 239.4 9.9 4.9e-71 239.2 9.9 1.0 1 0 0 1 1 1 1 Ceramidase Abhydrolase_1 PF00561.20 ORY43847.1 - 5.4e-14 52.5 0.9 1e-12 48.2 0.9 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY43847.1 - 9.8e-09 36.1 0.1 2.1e-08 35.0 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY43847.1 - 9e-08 31.7 0.5 1.3e-07 31.1 0.5 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Lipase_3 PF01764.25 ORY43847.1 - 0.0075 16.1 0.1 0.016 15.1 0.1 1.6 1 1 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 ORY43847.1 - 0.022 14.3 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) FAD_binding_3 PF01494.19 ORY43849.1 - 4.5e-24 85.3 1.0 3.5e-17 62.7 0.4 2.2 1 1 1 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ORY43849.1 - 1.8e-07 30.7 1.6 0.015 14.6 0.3 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY43849.1 - 6.2e-05 22.7 1.2 8.8e-05 22.2 0.2 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY43849.1 - 0.00017 21.8 0.2 0.00041 20.5 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 ORY43849.1 - 0.00091 18.4 0.0 0.033 13.2 0.0 2.1 1 1 1 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.27 ORY43849.1 - 0.0033 18.0 0.0 0.15 12.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY43849.1 - 0.0038 16.4 0.2 0.0066 15.6 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 ORY43849.1 - 0.0087 15.2 0.4 0.015 14.4 0.1 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 ORY43849.1 - 0.01 14.5 1.0 0.81 8.3 0.1 2.5 3 0 0 3 3 3 0 HI0933-like protein 3HCDH_N PF02737.18 ORY43849.1 - 0.022 14.6 0.1 0.038 13.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 ORY43849.1 - 0.026 14.2 0.2 0.06 13.0 0.1 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 ORY43849.1 - 0.05 12.9 0.2 0.62 9.3 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ldh_1_N PF00056.23 ORY43849.1 - 0.15 12.1 0.1 0.33 11.0 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 ORY43849.1 - 0.19 10.6 1.6 7.1 5.4 0.0 2.6 3 0 0 3 3 3 0 Tryptophan halogenase NYN PF01936.18 ORY43850.1 - 0.0012 19.3 0.0 0.0019 18.7 0.0 1.3 1 0 0 1 1 1 1 NYN domain zf-C2H2_aberr PF17017.5 ORY43850.1 - 0.039 14.1 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 Aberrant zinc-finger Peptidase_M16_C PF05193.21 ORY43851.1 - 1.5e-19 70.7 0.0 4.6e-11 43.1 0.0 3.6 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ORY43851.1 - 5.4e-14 52.4 0.0 7.2e-12 45.5 0.0 3.2 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.11 ORY43851.1 - 0.00013 21.2 2.8 0.00014 21.0 0.7 2.1 2 1 0 2 2 2 1 Peptidase M16C associated RXT2_N PF08595.11 ORY43851.1 - 0.085 12.9 3.3 0.15 12.0 3.3 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Pox_RNA_Pol_19 PF05320.12 ORY43851.1 - 0.23 11.4 5.3 0.43 10.5 5.3 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit CENP-B_dimeris PF09026.10 ORY43851.1 - 0.28 11.6 17.6 6.2 7.3 17.6 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FAM176 PF14851.6 ORY43851.1 - 0.5 10.0 2.9 0.95 9.1 2.9 1.4 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.13 ORY43851.1 - 1.2 9.0 9.2 0.68 9.8 7.2 1.5 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF2457 PF10446.9 ORY43851.1 - 2.2 7.3 17.6 3.5 6.7 17.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop25 PF09805.9 ORY43851.1 - 5.1 7.6 7.1 9.7 6.7 7.1 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) SDA1 PF05285.12 ORY43851.1 - 7 6.0 13.0 11 5.3 13.0 1.2 1 0 0 1 1 1 0 SDA1 adh_short PF00106.25 ORY43853.1 - 8e-40 136.4 0.5 1.2e-39 135.9 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY43853.1 - 3.2e-21 76.0 0.8 4.5e-21 75.5 0.4 1.4 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY43853.1 - 7.5e-05 22.7 0.1 0.00012 22.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Glyoxalase_6 PF18029.1 ORY43853.1 - 0.0055 17.5 0.0 0.011 16.5 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain Elf4 PF07011.11 ORY43853.1 - 0.087 12.7 0.5 0.18 11.7 0.5 1.5 1 0 0 1 1 1 0 Early Flowering 4 domain TMEM206 PF15122.6 ORY43853.1 - 0.092 11.9 0.2 0.14 11.3 0.2 1.2 1 0 0 1 1 1 0 TMEM206 protein family DUF4926 PF16277.5 ORY43853.1 - 0.094 12.1 0.1 0.23 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4926) Epimerase PF01370.21 ORY43853.1 - 0.099 12.1 0.5 0.14 11.6 0.5 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FMO-like PF00743.19 ORY43854.1 - 5.6e-14 51.5 0.5 3.2e-12 45.6 0.1 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 ORY43854.1 - 5e-12 45.6 0.1 2.7e-07 30.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY43854.1 - 4.6e-07 30.0 0.4 4.3e-06 26.9 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORY43854.1 - 4.8e-07 29.3 3.3 1.6e-06 27.6 1.5 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY43854.1 - 4.3e-06 26.5 2.6 0.061 12.9 0.1 3.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 ORY43854.1 - 1.5e-05 24.3 0.3 1.5e-05 24.3 0.3 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 ORY43854.1 - 0.0025 17.8 1.7 3.5 7.6 0.2 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding F-box PF00646.33 ORY43854.1 - 0.014 15.3 0.6 0.037 13.9 0.6 1.6 1 0 0 1 1 1 0 F-box domain FAD_binding_2 PF00890.24 ORY43854.1 - 0.031 13.4 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 ORY43854.1 - 0.034 13.5 0.3 0.68 9.2 0.1 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 ORY43854.1 - 0.12 11.4 0.5 8.5 5.3 0.1 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Transket_pyr PF02779.24 ORY43855.1 - 5.5e-44 150.0 0.0 8.3e-44 149.4 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORY43855.1 - 4.1e-42 143.0 0.1 2.3e-41 140.6 0.1 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain PFOR_II PF17147.4 ORY43855.1 - 0.0027 18.0 0.1 0.0096 16.2 0.0 1.9 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II Zn_dep_PLPC PF00882.18 ORY43856.1 - 8.6e-17 61.7 4.1 1.5e-16 61.0 4.1 1.3 1 0 0 1 1 1 1 Zinc dependent phospholipase C FG-GAP PF01839.23 ORY43856.1 - 1.8e-14 53.5 13.6 9.2e-08 32.1 3.1 4.7 5 0 0 5 5 5 2 FG-GAP repeat VCBS PF13517.6 ORY43856.1 - 2e-05 25.1 2.8 2e-05 25.1 2.8 4.8 5 1 0 5 5 5 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 PF14312.6 ORY43856.1 - 0.00041 20.5 3.8 0.11 12.8 0.1 3.2 3 0 0 3 3 3 2 FG-GAP repeat CDP-OH_P_transf PF01066.21 ORY43856.1 - 0.13 13.1 0.0 2.9 8.7 0.0 2.4 2 0 0 2 2 2 0 CDP-alcohol phosphatidyltransferase TcdB_toxin_midN PF12256.8 ORY43856.1 - 0.48 9.8 2.0 4 6.8 0.0 2.5 3 0 0 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region Asparaginase_2 PF01112.18 ORY43857.1 - 4.4e-100 334.7 9.2 4.9e-100 334.5 9.2 1.0 1 0 0 1 1 1 1 Asparaginase Peptidase_S10 PF00450.22 ORY43858.1 - 1.3e-83 281.8 1.2 2.8e-83 280.7 1.2 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase PAN_1 PF00024.26 ORY43859.1 - 0.0012 18.8 1.1 0.018 15.0 0.1 2.3 2 0 0 2 2 2 2 PAN domain ArAE_2 PF10334.9 ORY43860.1 - 1.1e-08 35.3 0.1 1.1e-05 25.4 0.1 3.1 3 0 0 3 3 3 2 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 ORY43860.1 - 0.00027 20.1 2.0 0.00027 20.1 2.0 3.5 2 2 0 4 4 4 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 ORY43860.1 - 0.0012 18.9 6.5 0.0012 18.9 6.5 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 ORY43860.1 - 0.28 10.0 7.6 0.81 8.4 5.9 2.3 2 1 0 2 2 2 0 Aluminium activated malate transporter ArAE_2 PF10334.9 ORY43861.1 - 3e-11 43.6 0.3 3.4e-05 23.8 0.1 2.5 2 0 0 2 2 2 2 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 ORY43861.1 - 3e-07 29.9 1.2 3e-07 29.9 1.2 3.2 3 0 0 3 3 3 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 ORY43861.1 - 0.00043 20.4 8.7 0.00043 20.4 8.7 2.7 2 0 0 2 2 2 1 Fusaric acid resistance protein-like DUF948 PF06103.11 ORY43861.1 - 0.14 12.4 0.4 2 8.7 0.0 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) ALMT PF11744.8 ORY43861.1 - 0.34 9.7 14.0 0.29 9.9 5.8 2.9 2 1 1 3 3 3 0 Aluminium activated malate transporter ArAE_2 PF10334.9 ORY43862.1 - 2.5e-12 47.1 0.4 2.5e-06 27.5 0.1 2.8 2 0 0 2 2 2 2 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 ORY43862.1 - 7.7e-07 28.5 11.8 1.3e-06 27.7 0.4 3.7 3 0 0 3 3 3 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 ORY43862.1 - 0.0016 18.6 11.4 0.0016 18.6 11.4 3.0 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ANF_receptor PF01094.28 ORY43863.1 - 5.4e-12 45.5 0.0 8.4e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 ORY43864.1 - 1e-18 68.0 26.5 1.7e-18 67.2 26.5 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR PSII PF00421.19 ORY43864.1 - 0.00083 18.2 0.0 0.0016 17.2 0.0 1.4 1 0 0 1 1 1 1 Photosystem II protein Pox_A14 PF05767.12 ORY43864.1 - 0.0036 17.4 1.8 0.0036 17.4 1.8 3.5 2 2 2 4 4 4 1 Poxvirus virion envelope protein A14 DUF3357 PF11837.8 ORY43864.1 - 0.077 13.5 0.0 0.48 10.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DsbD PF02683.15 ORY43864.1 - 0.7 9.8 13.3 0.35 10.7 8.8 2.4 1 1 1 2 2 2 0 Cytochrome C biogenesis protein transmembrane region YtpI PF14007.6 ORY43864.1 - 7 6.9 16.9 0.45 10.7 8.4 3.0 2 1 1 3 3 3 0 YtpI-like protein Rad1 PF02144.16 ORY43865.1 - 7.2e-34 117.1 0.0 8.7e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 GRIP PF01465.20 ORY43866.1 - 1.5e-13 50.4 0.2 4.4e-13 48.9 0.2 1.9 1 0 0 1 1 1 1 GRIP domain DUF4795 PF16043.5 ORY43866.1 - 0.00011 21.9 17.3 0.00011 21.9 17.3 9.5 4 2 5 10 10 10 2 Domain of unknown function (DUF4795) FUSC PF04632.12 ORY43866.1 - 0.00046 18.9 5.8 0.00046 18.9 5.8 5.8 1 1 3 5 5 5 1 Fusaric acid resistance protein family Tropomyosin_1 PF12718.7 ORY43866.1 - 0.0046 17.1 3.8 0.0046 17.1 3.8 13.8 3 2 10 13 13 13 1 Tropomyosin like MscS_porin PF12795.7 ORY43866.1 - 0.0049 16.4 35.2 0.0049 16.4 35.2 9.8 4 2 4 9 9 9 2 Mechanosensitive ion channel porin domain DUF4097 PF13349.6 ORY43867.1 - 0.00043 19.7 3.5 0.13 11.6 0.0 2.7 2 1 0 3 3 3 2 Putative adhesin DUF2706 PF10913.8 ORY43867.1 - 0.15 12.0 0.0 0.38 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2706) Ribosomal_S17e PF00833.18 ORY43868.1 - 1.4e-61 205.8 0.2 1.7e-61 205.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 Mre11_DNA_bind PF04152.14 ORY43869.1 - 8.1e-54 182.5 2.3 1.1e-53 182.0 2.3 1.2 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 ORY43869.1 - 4.1e-14 53.6 0.5 8.4e-14 52.6 0.5 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY43869.1 - 9.3e-06 25.9 0.0 3.9e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sec15 PF04091.12 ORY43869.1 - 0.13 11.7 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like TPR_1 PF00515.28 ORY43870.1 - 4.2e-21 73.8 1.6 0.00051 19.8 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORY43870.1 - 2.1e-18 64.9 0.1 9.8e-05 22.3 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY43870.1 - 1e-17 62.7 1.5 0.0049 16.9 1.1 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORY43870.1 - 1.4e-15 56.7 0.1 9.4e-10 38.0 0.1 4.6 3 1 1 4 4 4 1 TPR repeat TPR_14 PF13428.6 ORY43870.1 - 7.9e-10 38.7 0.4 0.0028 18.4 0.0 4.9 3 3 3 6 6 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY43870.1 - 3.5e-09 37.1 0.1 0.00093 19.8 0.1 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY43870.1 - 4.9e-09 36.4 3.3 1.7 9.0 0.0 5.4 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY43870.1 - 4.2e-08 33.6 0.0 0.066 13.7 0.0 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY43870.1 - 4.1e-07 29.6 1.4 0.17 12.0 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY43870.1 - 9.8e-07 28.7 0.7 0.0015 18.7 0.0 4.9 4 2 1 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 ORY43870.1 - 1.2e-06 28.0 0.2 2e-05 24.0 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat ChAPs PF09295.10 ORY43870.1 - 4.9e-05 22.5 0.0 0.00011 21.3 0.0 1.6 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.6 ORY43870.1 - 9.5e-05 22.5 0.6 1 9.6 0.1 3.9 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY43870.1 - 0.00042 20.8 4.3 28 5.6 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY43870.1 - 0.0024 17.7 0.6 2.3 8.2 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.18 ORY43870.1 - 0.013 15.6 0.1 39 4.4 0.0 3.5 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 ORY43870.1 - 0.032 14.6 0.1 0.19 12.2 0.0 2.2 2 0 0 2 2 2 0 Bacterial transcriptional activator domain ANAPC3 PF12895.7 ORY43870.1 - 0.063 13.5 4.7 0.14 12.4 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 ORY43870.1 - 0.076 13.1 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) Sel1 PF08238.12 ORY43870.1 - 0.14 12.9 1.0 54 4.7 0.1 3.8 3 0 0 3 3 3 0 Sel1 repeat MFS_1 PF07690.16 ORY43871.1 - 5.5e-16 58.4 26.1 7.3e-16 58.0 26.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.13 ORY43871.1 - 0.0076 15.8 10.8 0.01 15.4 10.8 1.1 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 ORY43872.1 - 4.1e-27 95.0 47.4 1.2e-17 63.9 22.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GHMP_kinases_C PF08544.13 ORY43872.1 - 0.066 13.6 0.1 0.17 12.3 0.1 1.6 1 0 0 1 1 1 0 GHMP kinases C terminal DUF2838 PF10998.8 ORY43873.1 - 1.2e-34 118.8 9.5 1.2e-34 118.8 9.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) TRAPPC-Trs85 PF12739.7 ORY43873.1 - 7.2e-33 114.1 11.4 5.2e-19 68.5 7.3 3.2 1 1 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit ubiquitin PF00240.23 ORY43874.1 - 5.6e-06 26.0 0.0 8.4e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY43874.1 - 0.024 14.5 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 ORY43874.1 - 0.088 13.2 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain His_biosynth PF00977.21 ORY43876.1 - 3.6e-40 137.9 3.7 4.7e-39 134.2 3.7 2.4 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 ORY43876.1 - 9.6e-24 84.2 0.0 1.6e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 ORY43876.1 - 3.3e-07 30.1 0.0 1.2e-06 28.3 0.0 1.8 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 ORY43876.1 - 4.2e-07 30.0 0.0 7e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 ORY43876.1 - 0.07 12.9 0.1 1.4 8.6 0.0 2.5 3 0 0 3 3 3 0 Peptidase C26 Diphthami_syn_2 PF01902.17 ORY43876.1 - 0.11 12.0 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Diphthamide synthase Mitofilin PF09731.9 ORY43877.1 - 2.4e-47 162.2 57.6 4.2e-38 131.6 0.1 3.2 1 1 2 3 3 3 3 Mitochondrial inner membrane protein Phage_Mu_Gam PF07352.12 ORY43877.1 - 0.0079 16.1 6.5 0.0079 16.1 6.5 2.9 2 1 0 2 2 2 1 Bacteriophage Mu Gam like protein DinB_2 PF12867.7 ORY43877.1 - 0.38 11.3 4.7 1.3 9.5 0.5 3.1 3 0 0 3 3 3 0 DinB superfamily LprI PF07007.12 ORY43877.1 - 2.6 8.8 16.7 1 10.1 5.0 2.9 2 0 0 2 2 2 0 Lysozyme inhibitor LprI HIG_1_N PF04588.13 ORY43878.1 - 1.2e-05 25.5 0.9 1.3e-05 25.3 0.9 1.0 1 0 0 1 1 1 1 Hypoxia induced protein conserved region NFACT-R_1 PF05670.13 ORY43943.1 - 1.8e-20 73.6 0.0 8.4e-20 71.5 0.0 2.0 2 0 0 2 2 2 1 NFACT protein RNA binding domain FbpA PF05833.11 ORY43943.1 - 1.3e-10 40.7 0.7 1.9e-10 40.1 0.7 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) YL1 PF05764.13 ORY43943.1 - 0.0067 16.6 6.8 0.0067 16.6 6.8 1.7 2 0 0 2 2 2 1 YL1 nuclear protein DUF1943 PF09172.11 ORY43943.1 - 0.008 15.4 0.1 0.012 14.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) Spt5_N PF11942.8 ORY43943.1 - 0.063 14.3 6.4 0.12 13.3 6.4 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.14 ORY43943.1 - 0.43 8.8 5.7 0.64 8.2 5.7 1.1 1 0 0 1 1 1 0 CDC45-like protein T3SS_needle_E PF08988.10 ORY43943.1 - 2.2 8.5 6.2 22 5.3 0.3 2.4 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle FbpA PF05833.11 ORY43944.1 - 0.076 11.8 2.0 0.49 9.1 0.0 2.0 2 0 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) cobW PF02492.19 ORY43948.1 - 2.9e-21 75.9 0.2 5.2e-21 75.0 0.2 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 ORY43948.1 - 0.00026 20.0 6.2 0.019 13.9 0.0 2.6 3 0 0 3 3 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 ORY43948.1 - 0.0011 18.6 1.0 0.05 13.1 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 ORY43948.1 - 0.0022 18.4 0.0 0.0022 18.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 ORY43948.1 - 0.0054 17.2 0.2 0.0054 17.2 0.2 2.4 2 1 1 3 3 3 1 ABC transporter AAA_18 PF13238.6 ORY43948.1 - 0.0058 17.2 1.7 0.013 16.0 0.1 2.3 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 ORY43948.1 - 0.0079 16.1 0.1 0.015 15.2 0.1 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain DUF4175 PF13779.6 ORY43948.1 - 0.0097 13.9 10.5 0.012 13.6 10.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) TsaE PF02367.17 ORY43948.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 ORY43948.1 - 0.012 16.0 0.6 0.024 15.0 0.1 1.7 2 0 0 2 2 1 0 AAA ATPase domain AAA_23 PF13476.6 ORY43948.1 - 0.015 15.8 0.0 0.015 15.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORY43948.1 - 0.021 14.4 0.0 0.021 14.4 0.0 1.6 2 0 0 2 2 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 ORY43948.1 - 0.022 14.8 0.8 0.031 14.3 0.0 1.6 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) PRK PF00485.18 ORY43948.1 - 0.023 14.4 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.23 ORY43948.1 - 0.028 14.5 0.0 0.081 13.0 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 ORY43948.1 - 0.028 14.3 0.1 0.057 13.3 0.1 1.5 1 0 0 1 1 1 0 NTPase RsgA_GTPase PF03193.16 ORY43948.1 - 0.035 14.0 1.6 4.4 7.2 0.0 2.6 3 0 0 3 3 3 0 RsgA GTPase RNA_helicase PF00910.22 ORY43948.1 - 0.038 14.4 1.3 0.073 13.5 0.0 2.0 2 0 0 2 2 2 0 RNA helicase KAP_NTPase PF07693.14 ORY43948.1 - 0.046 13.0 0.6 0.16 11.1 0.0 1.9 2 1 0 2 2 2 0 KAP family P-loop domain CbiA PF01656.23 ORY43948.1 - 0.048 13.7 0.1 0.084 12.9 0.1 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain dNK PF01712.19 ORY43948.1 - 0.051 13.4 0.0 0.051 13.4 0.0 1.7 2 0 0 2 2 1 0 Deoxynucleoside kinase NACHT PF05729.12 ORY43948.1 - 0.079 12.9 0.0 0.079 12.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.6 ORY43948.1 - 0.079 12.7 2.2 0.88 9.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain Flagellin_IN PF07196.13 ORY43948.1 - 0.087 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Flagellin hook IN motif AAA_29 PF13555.6 ORY43948.1 - 0.097 12.4 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 ORY43948.1 - 0.098 11.7 1.0 0.38 9.8 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein PqqD PF05402.12 ORY43948.1 - 0.12 12.7 0.0 12 6.3 0.0 2.3 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) ATP_bind_1 PF03029.17 ORY43948.1 - 0.18 11.6 1.5 0.19 11.5 0.0 1.8 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 ORY43948.1 - 0.18 10.9 0.0 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 ORY43948.1 - 0.21 11.7 0.0 0.21 11.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 ORY43948.1 - 0.21 11.3 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein MobB PF03205.14 ORY43948.1 - 0.32 10.9 0.0 0.32 10.9 0.0 1.7 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B TFIIA PF03153.13 ORY43948.1 - 0.46 10.4 16.2 0.63 10.0 16.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_28 PF13521.6 ORY43948.1 - 0.49 10.6 0.0 0.49 10.6 0.0 2.5 3 0 0 3 3 1 0 AAA domain Spt20 PF12090.8 ORY43948.1 - 0.53 9.9 18.1 0.81 9.2 18.1 1.2 1 0 0 1 1 1 0 Spt20 family Zip PF02535.22 ORY43948.1 - 3 7.0 6.0 4.1 6.5 6.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter zinc_ribbon_9 PF14369.6 ORY43949.1 - 0.26 11.6 19.4 3.2 8.1 0.1 6.1 5 0 0 5 5 5 0 zinc-ribbon LBP_BPI_CETP PF01273.25 ORY43951.1 - 1e-09 38.2 0.5 1.4e-09 37.7 0.5 1.2 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain LBP_BPI_CETP PF01273.25 ORY43952.1 - 7.3e-10 38.7 0.1 1.3e-09 37.9 0.1 1.3 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain TPR_12 PF13424.6 ORY43954.1 - 1.6e-08 34.7 7.6 8.2e-05 22.8 0.4 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY43954.1 - 0.00051 19.8 4.4 0.41 10.6 0.5 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY43954.1 - 0.03 14.8 4.9 1.8 9.1 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY43954.1 - 0.048 13.9 1.1 16 6.1 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 ORY43954.1 - 0.051 14.2 5.8 1.5 9.7 3.7 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY43954.1 - 0.42 10.8 8.4 5.2 7.4 0.9 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY43954.1 - 2 9.4 5.2 53 5.0 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Ysc84 PF04366.12 ORY43956.1 - 4.9e-34 116.8 0.7 6.5e-34 116.4 0.7 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator Dynein_light PF01221.18 ORY43957.1 - 3.2e-23 81.9 0.3 3.8e-23 81.6 0.3 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 PCI PF01399.27 ORY43958.1 - 4.6e-15 56.0 1.6 1.5e-14 54.4 0.0 2.6 2 1 0 2 2 2 1 PCI domain eIF3m_C_helix PF18005.1 ORY43958.1 - 4.9e-07 29.3 0.3 1.1e-06 28.2 0.3 1.7 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix Peptidase_S8 PF00082.22 ORY43959.1 - 1.8e-50 171.9 4.5 3.4e-50 171.0 4.5 1.5 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 ORY43959.1 - 1.1e-11 45.4 1.4 1.1e-11 45.4 1.4 1.7 2 0 0 2 2 2 1 Fn3-like domain PA PF02225.22 ORY43959.1 - 4.4e-07 29.8 0.2 1.2e-06 28.4 0.2 1.8 1 0 0 1 1 1 1 PA domain FixG_C PF11614.8 ORY43959.1 - 0.023 14.9 0.2 0.051 13.8 0.2 1.5 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase MFS_1 PF07690.16 ORY43960.1 - 6.7e-23 81.2 35.6 6.7e-23 81.2 35.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY43960.1 - 3.4e-05 22.9 12.7 3.4e-05 22.9 12.7 2.4 1 1 1 2 2 2 1 Sugar (and other) transporter AC_N PF16214.5 ORY43960.1 - 2.5 7.2 5.8 4 6.5 5.8 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region VHS PF00790.19 ORY43961.1 - 4.6e-15 55.7 0.0 8e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 VHS domain Synuclein PF01387.17 ORY43961.1 - 0.06 13.6 0.4 0.11 12.7 0.4 1.3 1 0 0 1 1 1 0 Synuclein Ysc84 PF04366.12 ORY43963.1 - 5.4e-37 126.4 0.3 7.5e-37 125.9 0.3 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator Ysc84 PF04366.12 ORY43964.1 - 1.2e-38 131.7 0.2 1.7e-38 131.3 0.2 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator Glycos_transf_1 PF00534.20 ORY43964.1 - 0.028 13.9 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 DinB PF05163.12 ORY43965.1 - 2e-18 66.9 1.0 1.3e-15 57.8 0.2 2.6 2 2 0 2 2 2 2 DinB family DinB_2 PF12867.7 ORY43965.1 - 9.9e-07 29.3 0.1 2.3e-06 28.1 0.1 1.6 1 0 0 1 1 1 1 DinB superfamily DUF664 PF04978.12 ORY43965.1 - 3.4e-06 27.5 0.3 1.9e-05 25.2 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF664) VHS PF00790.19 ORY43966.1 - 0.042 13.7 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 VHS domain ABC_membrane PF00664.23 ORY43967.1 - 1.9e-55 188.4 32.3 6.9e-32 111.2 13.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY43967.1 - 3.2e-51 173.4 0.1 1.3e-30 106.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ORY43967.1 - 1.6e-08 34.7 4.1 0.0035 17.2 0.2 4.4 5 0 0 5 5 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY43967.1 - 1.8e-08 34.1 4.1 0.09 12.2 0.0 4.1 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY43967.1 - 4.1e-07 29.6 1.0 0.026 14.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY43967.1 - 1.9e-06 27.9 0.4 0.019 15.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 ORY43967.1 - 7.2e-06 26.6 0.4 0.18 12.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 ORY43967.1 - 5.6e-05 23.3 2.6 0.0074 16.4 0.4 2.4 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 ORY43967.1 - 5.7e-05 23.1 0.2 0.073 13.0 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 ORY43967.1 - 7.2e-05 22.7 0.3 0.011 15.5 0.3 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY43967.1 - 0.00014 22.1 0.8 0.48 10.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.18 ORY43967.1 - 0.00033 20.1 0.3 0.14 11.5 0.2 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.6 ORY43967.1 - 0.0038 17.6 0.0 4.3 7.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 ORY43967.1 - 0.005 16.6 0.2 2.2 7.9 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.6 ORY43967.1 - 0.0054 16.3 0.2 2.5 7.6 0.1 2.4 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 ORY43967.1 - 0.0062 16.7 0.3 3.5 7.9 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 ORY43967.1 - 0.0092 15.5 0.2 4.7 6.7 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF87 PF01935.17 ORY43967.1 - 0.015 15.4 3.1 0.25 11.4 0.1 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain MeaB PF03308.16 ORY43967.1 - 0.015 14.3 0.2 0.093 11.7 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 ORY43967.1 - 0.031 13.5 0.5 2.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_27 PF13514.6 ORY43967.1 - 0.058 13.0 0.1 4.3 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 ORY43967.1 - 0.063 12.9 0.7 2.1 7.9 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.16 ORY43967.1 - 0.078 12.3 0.4 9.9 5.4 0.0 2.4 2 0 0 2 2 2 0 AIG1 family AAA_24 PF13479.6 ORY43967.1 - 0.12 12.1 0.2 4.7 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 ORY43967.1 - 0.12 12.1 2.3 7.8 6.2 0.1 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 ORY43967.1 - 0.12 11.5 0.8 0.56 9.3 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain IIGP PF05049.13 ORY43967.1 - 0.22 10.5 1.4 8.8 5.3 0.1 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) BatA PF07584.11 ORY43967.1 - 0.3 11.5 1.5 5.6 7.4 0.1 2.9 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal NACHT PF05729.12 ORY43967.1 - 0.62 10.0 4.3 1.9 8.4 0.2 3.0 3 0 0 3 3 3 0 NACHT domain ABC_ATPase PF09818.9 ORY43967.1 - 0.77 8.5 4.4 7.7 5.2 0.1 3.0 3 0 0 3 3 3 0 Predicted ATPase of the ABC class ABC_tran PF00005.27 ORY43968.1 - 9.4e-52 175.2 0.1 4.6e-31 108.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORY43968.1 - 1.2e-50 172.7 40.5 2.1e-29 103.0 16.0 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 ORY43968.1 - 1e-09 38.6 1.3 0.0013 18.6 0.0 4.0 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY43968.1 - 3.1e-09 36.6 2.7 0.096 12.1 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY43968.1 - 1.8e-07 30.8 1.7 0.016 14.9 0.4 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY43968.1 - 3.5e-07 30.3 0.8 0.018 15.1 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 ORY43968.1 - 5.7e-06 27.0 0.2 0.17 12.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ORY43968.1 - 1.6e-05 24.8 0.9 0.016 15.1 0.5 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 ORY43968.1 - 5e-05 23.4 2.4 0.0083 16.2 0.4 2.4 2 0 0 2 2 2 1 Dynamin family AAA_22 PF13401.6 ORY43968.1 - 9.4e-05 22.7 0.9 0.99 9.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ORY43968.1 - 0.00058 20.3 0.1 0.95 9.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 ORY43968.1 - 0.001 18.8 1.0 0.12 12.1 0.6 2.2 2 0 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 ORY43968.1 - 0.0012 18.1 0.5 0.66 9.1 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Roc PF08477.13 ORY43968.1 - 0.0013 18.9 0.2 2.9 8.1 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 ORY43968.1 - 0.0018 17.7 0.3 0.75 9.1 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_30 PF13604.6 ORY43968.1 - 0.0019 17.9 0.3 2.1 8.0 0.0 2.7 3 0 0 3 3 2 2 AAA domain MeaB PF03308.16 ORY43968.1 - 0.0023 17.0 0.4 0.069 12.1 0.0 2.3 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 ORY43968.1 - 0.0063 16.0 1.1 2.2 7.8 0.3 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 ORY43968.1 - 0.009 15.2 0.2 0.48 9.6 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.12 ORY43968.1 - 0.014 14.6 1.2 2.7 7.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 ORY43968.1 - 0.02 14.4 0.4 5.4 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 ORY43968.1 - 0.046 13.8 5.1 0.26 11.3 0.2 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AIG1 PF04548.16 ORY43968.1 - 0.05 12.9 1.3 9.1 5.5 0.0 2.5 2 0 0 2 2 2 0 AIG1 family cobW PF02492.19 ORY43968.1 - 0.051 13.2 2.2 0.87 9.1 0.4 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 ORY43968.1 - 0.053 13.3 0.7 8.4 6.1 0.2 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 ORY43968.1 - 0.086 12.6 0.5 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 ORY43968.1 - 0.13 12.8 0.1 30 5.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Complex1_LYR_2 PF13233.6 ORY43968.1 - 0.14 13.0 0.0 6.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Complex1_LYR-like AAA_27 PF13514.6 ORY43968.1 - 0.14 11.7 0.1 9.4 5.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORY43968.1 - 0.14 12.5 0.1 13 6.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.18 ORY43968.1 - 0.19 11.4 0.2 13 5.4 0.0 2.6 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 ORY43968.1 - 0.19 11.7 0.3 15 5.6 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 ORY43968.1 - 0.25 10.6 0.8 18 4.5 0.2 2.2 2 0 0 2 2 2 0 Septin ABC_ATPase PF09818.9 ORY43968.1 - 1.7 7.3 6.7 4.7 5.9 0.0 3.1 4 0 0 4 4 4 0 Predicted ATPase of the ABC class NACHT PF05729.12 ORY43968.1 - 2.4 8.0 4.8 4 7.3 0.4 2.8 3 0 0 3 3 3 0 NACHT domain Ysc84 PF04366.12 ORY43969.1 - 3.1e-45 153.1 0.1 4.6e-45 152.5 0.1 1.3 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 ORY43969.1 - 7.7e-15 54.2 0.1 1.5e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY43969.1 - 9.4e-13 47.8 0.1 1.5e-12 47.1 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY43969.1 - 2.7e-09 36.6 0.0 5.3e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Gti1_Pac2 PF09729.9 ORY43970.1 - 1.6e-11 44.7 0.1 2.1e-09 37.7 0.1 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family BORCS6 PF10157.9 ORY43972.1 - 5.6e-10 39.6 1.1 6.1e-10 39.5 1.1 1.0 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 Vitellogenin_N PF01347.22 ORY43972.1 - 0.012 14.0 0.2 0.014 13.9 0.2 1.0 1 0 0 1 1 1 0 Lipoprotein amino terminal region Amino_oxidase PF01593.24 ORY43974.1 - 6e-71 240.1 0.1 1.1e-70 239.2 0.1 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY43974.1 - 8.1e-09 35.6 0.1 1.6e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY43974.1 - 0.0018 17.5 0.2 0.47 9.6 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY43974.1 - 0.0053 16.4 1.3 0.012 15.2 1.3 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 ORY43974.1 - 0.0089 15.3 0.6 0.047 12.9 0.3 2.2 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 ORY43974.1 - 0.087 11.5 0.5 0.13 11.0 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 ORY43974.1 - 0.27 10.5 0.6 0.51 9.5 0.6 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Acetyltransf_7 PF13508.7 ORY43975.1 - 0.0093 16.4 0.0 0.013 15.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY43975.1 - 0.028 14.6 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY43975.1 - 0.059 13.3 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain tRNA-synt_1c PF00749.21 ORY43975.1 - 0.16 10.8 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain GST_C_2 PF13410.6 ORY43976.1 - 0.00031 20.7 0.1 0.00039 20.4 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY43976.1 - 0.0092 16.2 0.1 0.011 16.0 0.1 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY43976.1 - 0.03 14.5 0.0 0.034 14.3 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY43977.1 - 2e-05 24.7 0.1 3.1e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY43977.1 - 0.0021 18.2 0.1 0.0036 17.5 0.0 1.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Amino_oxidase PF01593.24 ORY43978.1 - 4.4e-65 220.7 0.0 4.9e-47 161.2 0.1 2.0 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY43978.1 - 5.5e-12 45.7 0.0 1.3e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ORY43978.1 - 4.6e-05 22.3 0.8 7.1e-05 21.7 0.8 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 ORY43978.1 - 7.5e-05 22.1 1.1 0.00074 18.9 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 ORY43978.1 - 0.00025 20.4 0.3 0.00041 19.7 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 ORY43978.1 - 0.00046 19.9 0.6 0.0017 18.0 0.5 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY43978.1 - 0.00094 18.5 0.1 0.0026 17.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY43978.1 - 0.002 17.4 0.3 0.003 16.8 0.3 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 ORY43978.1 - 0.0039 16.6 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORY43978.1 - 0.0061 17.1 0.2 0.014 15.9 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY43978.1 - 0.017 14.4 0.2 0.035 13.4 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY43978.1 - 0.019 14.1 1.3 0.03 13.4 1.3 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 ORY43978.1 - 0.021 13.9 0.7 0.032 13.3 0.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 ORY43978.1 - 0.04 13.0 0.2 0.071 12.1 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 ORY43978.1 - 0.076 12.7 0.2 0.25 11.0 0.2 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Acetyltransf_7 PF13508.7 ORY43980.1 - 1.3e-06 28.7 0.0 1.8e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY43980.1 - 2.3e-05 24.6 0.0 2.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY43980.1 - 0.00012 22.0 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY43980.1 - 0.00028 20.8 0.0 0.00048 20.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 ORY43980.1 - 0.06 14.0 0.0 0.073 13.7 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Ysc84 PF04366.12 ORY43981.1 - 5.9e-23 81.0 0.1 6.7e-19 67.9 0.1 2.0 1 1 1 2 2 2 2 Las17-binding protein actin regulator MFS_MOT1 PF16983.5 ORY43981.1 - 0.038 14.4 0.0 0.06 13.8 0.0 1.3 1 0 0 1 1 1 0 Molybdate transporter of MFS superfamily MFS_1 PF07690.16 ORY43982.1 - 1.9e-23 83.0 25.0 2.3e-22 79.4 17.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Acetyltransf_10 PF13673.7 ORY43982.1 - 3.9e-06 26.8 0.0 7.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY43982.1 - 3.9e-06 27.0 0.0 7.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY43982.1 - 4.8e-06 26.8 0.0 1.8e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 ORY43982.1 - 1.4e-05 25.1 0.0 3.7e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.7 ORY43982.1 - 0.0001 22.7 0.0 0.00023 21.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY43982.1 - 0.0001 22.2 0.0 0.00026 20.9 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Sugar_tr PF00083.24 ORY43982.1 - 0.0019 17.2 4.6 0.0029 16.6 3.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter UNC-93 PF05978.16 ORY43982.1 - 0.012 15.3 3.1 0.035 13.8 3.1 1.7 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 DUF1003 PF06210.11 ORY43982.1 - 0.061 13.4 0.0 0.2 11.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Ysc84 PF04366.12 ORY43984.1 - 5.7e-26 90.8 0.3 3.5e-25 88.2 0.3 1.9 1 1 0 1 1 1 1 Las17-binding protein actin regulator DGF-1_4 PF11024.8 ORY43984.1 - 0.092 13.6 0.2 0.24 12.2 0.1 1.7 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 Ysc84 PF04366.12 ORY43985.1 - 3.2e-41 140.1 0.1 4.4e-41 139.6 0.1 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator DUF4337 PF14235.6 ORY43986.1 - 0.11 12.6 0.1 0.16 12.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RNase_H PF00075.24 ORY43987.1 - 1.3e-16 61.1 0.0 2e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 RNase H MFS_1 PF07690.16 ORY43988.1 - 3.4e-12 46.0 25.0 1.8e-10 40.3 4.0 3.0 1 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1 PF07690.16 ORY43989.1 - 0.00011 21.3 31.8 0.00018 20.5 5.3 3.1 1 1 1 3 3 3 3 Major Facilitator Superfamily FKBP_C PF00254.28 ORY43990.1 - 1.8e-20 73.1 0.0 3.5e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase BTHB PF18410.1 ORY43990.1 - 2e-15 56.3 0.6 5.7e-15 54.9 0.6 1.8 1 0 0 1 1 1 1 Basic tilted helix bundle domain pP_pnuc_1 PF18165.1 ORY43990.1 - 0.019 14.9 0.1 0.027 14.3 0.1 1.3 1 0 0 1 1 1 0 Predicted pPIWI-associating nuclease ZirS_C PF16583.5 ORY43990.1 - 0.067 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain Ysc84 PF04366.12 ORY43992.1 - 9.1e-19 67.5 0.0 6.5e-13 48.5 0.0 2.2 1 1 1 2 2 2 2 Las17-binding protein actin regulator CUB PF00431.20 ORY43993.1 - 1.8e-13 50.8 0.2 3.1e-13 50.0 0.2 1.4 1 0 0 1 1 1 1 CUB domain Kelch_4 PF13418.6 ORY43993.1 - 1.2e-09 38.0 5.3 0.0028 17.6 0.4 5.0 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY43993.1 - 3.5e-09 36.6 8.6 5.8e-05 23.2 0.1 5.6 4 1 2 6 6 6 2 Kelch motif Kelch_1 PF01344.25 ORY43993.1 - 4.8e-09 35.7 0.8 0.00019 20.9 0.2 4.0 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.6 ORY43993.1 - 1.7e-08 34.2 2.3 0.0018 18.2 0.0 4.9 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 ORY43993.1 - 2.4e-06 27.3 1.2 0.012 15.6 0.0 4.8 5 0 0 5 5 5 1 Kelch motif Kelch_3 PF13415.6 ORY43993.1 - 8e-05 22.8 9.6 0.015 15.5 0.7 4.6 3 1 2 5 5 5 2 Galactose oxidase, central domain EGF_2 PF07974.13 ORY43993.1 - 0.00096 19.5 14.0 0.0022 18.3 14.0 1.7 1 0 0 1 1 1 1 EGF-like domain EB PF01683.18 ORY43993.1 - 0.0041 17.4 5.0 0.0096 16.2 5.0 1.7 1 1 0 1 1 1 1 EB module EGF_Tenascin PF18720.1 ORY43993.1 - 3.9 7.6 14.5 0.13 12.3 8.2 1.8 2 0 0 2 2 2 0 Tenascin EGF domain ParcG PF10274.9 ORY43994.1 - 2.9e-82 275.2 0.0 3.4e-82 275.0 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 ORY43994.1 - 0.0026 17.5 0.0 0.0035 17.0 0.0 1.2 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 VHS PF00790.19 ORY43994.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 VHS domain Forkhead PF00250.18 ORY43995.1 - 7e-17 61.5 0.8 2e-11 44.0 0.3 2.4 1 1 1 2 2 2 2 Forkhead domain FHA PF00498.26 ORY43995.1 - 1.3e-09 38.2 0.1 2.1e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 FHA domain Linker_histone PF00538.19 ORY43995.1 - 0.0058 17.0 0.1 0.012 16.0 0.1 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family ANF_receptor PF01094.28 ORY43996.1 - 6.7e-32 111.0 0.1 2.3e-31 109.2 0.0 1.7 2 0 0 2 2 2 1 Receptor family ligand binding region 7tm_3 PF00003.22 ORY43996.1 - 1.8e-14 54.1 26.4 1.8e-14 54.1 26.4 1.9 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 ORY43996.1 - 0.0032 17.2 0.1 0.0049 16.6 0.1 1.2 1 0 0 1 1 1 1 Periplasmic binding protein TPR_10 PF13374.6 ORY43997.1 - 3.1e-62 204.9 19.1 3.4e-10 39.5 0.0 9.7 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_12 PF13424.6 ORY43997.1 - 7.2e-57 189.6 27.8 2.3e-15 56.6 0.1 6.5 3 2 4 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 ORY43997.1 - 1.6e-18 65.3 7.4 0.027 14.5 0.1 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 ORY43997.1 - 6.7e-15 54.0 12.6 0.012 15.7 0.0 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 ORY43997.1 - 2.2e-11 43.0 8.8 0.35 10.8 0.1 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY43997.1 - 1.7e-10 40.2 8.0 3.1 8.1 0.0 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY43997.1 - 4.8e-08 32.8 9.0 0.00056 19.4 0.0 3.1 1 1 2 3 3 3 3 MalT-like TPR region TPR_4 PF07721.14 ORY43997.1 - 0.00015 22.1 0.0 0.97 10.3 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat Mitovir_RNA_pol PF05919.11 ORY43997.1 - 0.00018 20.8 0.1 0.0004 19.7 0.0 1.6 1 1 0 1 1 1 1 Mitovirus RNA-dependent RNA polymerase TPR_17 PF13431.6 ORY43997.1 - 0.00035 20.7 14.3 2.6 8.6 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY43997.1 - 0.0014 19.1 11.2 3.4 8.2 0.4 5.8 4 2 3 7 7 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY43997.1 - 0.0014 18.8 7.0 1 9.6 0.1 5.3 4 3 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_5 PF12688.7 ORY43997.1 - 0.0072 16.6 2.8 3.6 7.9 0.2 3.5 2 1 1 3 3 3 1 Tetratrico peptide repeat TPR_16 PF13432.6 ORY43997.1 - 0.0098 16.5 2.8 92 3.8 0.2 5.2 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 ORY43997.1 - 0.048 13.7 7.1 1e+02 3.0 0.1 6.0 6 1 0 6 6 6 0 Tetratricopeptide repeat ANAPC5 PF12862.7 ORY43997.1 - 0.097 12.7 1.7 2.5 8.3 0.1 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_14 PF13428.6 ORY43997.1 - 0.15 13.0 7.2 52 5.1 0.0 6.1 8 0 0 8 8 6 0 Tetratricopeptide repeat ArAE_2 PF10334.9 ORY43998.1 - 8e-09 35.7 0.1 9e-06 25.7 0.0 2.6 2 1 0 2 2 2 2 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 ORY43998.1 - 0.0014 18.7 5.3 0.0014 18.7 5.3 2.9 3 0 0 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 ORY43999.1 - 9.3e-11 42.0 0.8 1e-07 32.1 0.2 2.7 2 1 0 2 2 2 2 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 ORY43999.1 - 5.8e-07 28.9 8.2 0.00033 19.8 0.4 2.5 2 1 0 2 2 2 2 Putative ER transporter, 6TM, N-terminal FUSC PF04632.12 ORY43999.1 - 0.0014 17.3 2.5 0.0014 17.3 2.5 3.3 2 2 1 3 3 3 2 Fusaric acid resistance protein family Ras PF00071.22 ORY44000.1 - 4.4e-52 176.0 0.0 5.2e-52 175.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY44000.1 - 3.7e-29 101.4 0.0 5.4e-29 100.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY44000.1 - 9.2e-10 38.2 0.0 1.3e-09 37.7 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY44000.1 - 0.00032 20.7 0.0 0.00049 20.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY44000.1 - 0.0017 18.8 0.0 0.0045 17.4 0.0 1.6 1 1 0 2 2 2 1 AAA ATPase domain Gtr1_RagA PF04670.12 ORY44000.1 - 0.0076 15.6 0.0 0.0086 15.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 ORY44000.1 - 0.022 14.7 0.0 2.4 8.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase PDEase_I PF00233.19 ORY44001.1 - 1e-77 261.1 0.1 1.4e-77 260.6 0.1 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase CNV-Replicase_N PF16688.5 ORY44001.1 - 0.08 13.3 0.0 9.2 6.7 0.0 2.8 2 0 0 2 2 2 0 Replicase polyprotein N-term from Coronavirus nsp1 Pkinase PF00069.25 ORY44002.1 - 4.2e-68 229.6 0.0 5.1e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY44002.1 - 2.9e-32 112.0 0.0 3.8e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY44002.1 - 3.4e-07 29.9 0.1 1.7e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 ORY44002.1 - 0.00078 19.1 0.1 0.35 10.4 0.1 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 ORY44002.1 - 0.0065 15.5 0.1 0.017 14.1 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY44002.1 - 0.02 14.8 0.1 0.12 12.3 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 ORY44002.1 - 0.081 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NTP_transf_7 PF07984.12 ORY44004.1 - 0.01 15.1 0.0 0.012 14.9 0.0 1.0 1 0 0 1 1 1 0 Nucleotidyltransferase HSP70 PF00012.20 ORY44005.1 - 3.5e-226 752.1 12.8 1.2e-225 750.2 12.8 1.7 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY44005.1 - 1.9e-13 50.0 1.4 3.9e-11 42.3 0.3 2.5 2 0 0 2 2 2 2 MreB/Mbl protein Ribosomal_L9_C PF03948.14 ORY44005.1 - 0.034 14.6 0.6 0.12 12.9 0.2 2.1 2 0 0 2 2 2 0 Ribosomal protein L9, C-terminal domain DbpA PF03880.15 ORY44005.1 - 0.078 13.0 0.0 16 5.6 0.1 2.9 2 0 0 2 2 2 0 DbpA RNA binding domain FtsA PF14450.6 ORY44005.1 - 0.19 12.1 8.6 11 6.5 0.3 4.2 3 2 0 3 3 3 0 Cell division protein FtsA YkyA PF10368.9 ORY44005.1 - 1.5 8.5 17.7 0.13 11.9 12.3 1.8 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Seryl_tRNA_N PF02403.22 ORY44005.1 - 3.4 7.9 10.1 14 6.0 10.1 2.0 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ArAE_2_N PF10337.9 ORY44006.1 - 1.3e-09 37.6 0.9 2.6e-09 36.7 0.1 1.8 2 0 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 ORY44006.1 - 2.2e-06 27.7 0.5 0.0035 17.2 0.0 2.7 3 0 0 3 3 3 2 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 ORY44006.1 - 0.00024 21.2 10.5 0.00024 21.2 10.5 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 ORY44006.1 - 0.0041 15.7 0.0 0.0041 15.7 0.0 2.8 3 0 0 3 3 3 1 Fusaric acid resistance protein family Pex24p PF06398.11 ORY44006.1 - 0.041 12.9 0.2 0.041 12.9 0.2 1.8 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin GRDA PF04723.14 ORY44006.1 - 0.2 11.4 0.7 0.54 10.0 0.0 2.0 2 0 0 2 2 2 0 Glycine reductase complex selenoprotein A MMACHC PF16690.5 ORY44007.1 - 1.1e-05 25.2 0.7 7.2e-05 22.5 0.0 2.6 2 1 0 2 2 2 1 Methylmalonic aciduria and homocystinuria type C family TPR_10 PF13374.6 ORY44009.1 - 1.7e-44 148.5 3.4 3.8e-09 36.1 0.1 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 ORY44009.1 - 1.6e-41 140.4 2.3 2.2e-12 47.1 0.1 5.0 2 1 2 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.6 ORY44009.1 - 4.8e-11 41.9 1.3 0.094 12.8 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORY44009.1 - 1.4e-10 40.5 4.9 0.092 13.0 0.0 4.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY44009.1 - 1.1e-06 28.3 2.9 2.9 8.2 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY44009.1 - 1.4e-06 27.9 2.9 0.38 10.7 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORY44009.1 - 9.7e-06 25.6 4.1 7 7.3 0.2 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY44009.1 - 3.6e-05 24.2 3.4 3.1 8.4 0.0 4.8 3 2 3 6 6 6 3 Tetratricopeptide repeat Lipase_GDSL_2 PF13472.6 ORY44011.1 - 9.2e-41 140.2 0.0 3.3e-21 76.5 0.0 2.2 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY44011.1 - 3.2e-33 115.4 0.0 4.7e-16 59.4 0.0 2.3 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase CDT1 PF08839.11 ORY44013.1 - 6.8e-23 81.9 0.1 1.4e-22 80.8 0.1 1.6 1 0 0 1 1 1 1 DNA replication factor CDT1 like CDT1_C PF16679.5 ORY44013.1 - 5.7e-15 55.5 0.0 3.3e-14 53.1 0.0 2.4 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain Ni_hydr_CYTB PF01292.20 ORY44014.1 - 0.0037 16.9 9.8 0.0043 16.7 4.5 2.3 2 0 0 2 2 2 2 Prokaryotic cytochrome b561 E1-E2_ATPase PF00122.20 ORY44014.1 - 7 6.1 8.2 1.8 8.0 4.5 1.9 2 0 0 2 2 2 0 E1-E2 ATPase LRR_8 PF13855.6 ORY44015.1 - 1.5e-08 34.3 19.1 3.8e-05 23.4 6.4 3.0 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 ORY44015.1 - 2.5e-05 24.5 19.5 0.00085 19.7 2.0 4.0 2 2 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY44015.1 - 0.033 14.7 20.2 0.8 10.5 1.4 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat F-box PF00646.33 ORY44015.1 - 0.083 12.8 0.5 0.18 11.7 0.5 1.6 1 0 0 1 1 1 0 F-box domain LRR_6 PF13516.6 ORY44015.1 - 3.6 7.9 9.0 3.2 8.1 0.6 3.9 4 0 0 4 4 4 0 Leucine Rich repeat Methyltransf_21 PF05050.12 ORY44016.1 - 0.0046 17.0 0.0 0.007 16.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain DDE_Tnp_IS66_C PF13817.6 ORY44016.1 - 0.076 13.2 0.1 0.3 11.3 0.1 2.0 1 0 0 1 1 1 0 IS66 C-terminal element MCM PF00493.23 ORY44017.1 - 2.1e-79 265.7 0.0 3.3e-79 265.1 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY44017.1 - 4.2e-22 78.3 1.4 9.6e-22 77.2 1.4 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORY44017.1 - 5.5e-17 62.0 1.4 1e-16 61.1 1.4 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 ORY44017.1 - 2.1e-09 37.1 0.0 9.4e-06 25.1 0.0 2.5 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ORY44017.1 - 7e-06 26.1 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 ORY44017.1 - 0.0017 18.1 0.0 0.041 13.6 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 ORY44017.1 - 0.0037 17.1 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY44017.1 - 0.023 15.1 0.3 0.095 13.1 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 ORY44017.1 - 0.05 13.0 0.1 0.092 12.1 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.6 ORY44017.1 - 0.051 13.3 0.1 0.29 10.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain ToxB_N PF18224.1 ORY44017.1 - 0.099 12.6 0.4 0.29 11.1 0.4 1.7 1 0 0 1 1 1 0 ToxB N-terminal domain AAA_22 PF13401.6 ORY44017.1 - 0.12 12.7 0.1 0.39 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain zf-MYND PF01753.18 ORY44018.1 - 4.6e-08 33.0 19.3 4.6e-08 33.0 19.3 1.5 2 0 0 2 2 2 1 MYND finger DUF3337 PF11816.8 ORY44020.1 - 0.031 14.1 0.0 0.031 14.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) DUF485 PF04341.12 ORY44023.1 - 0.48 10.4 1.9 1.1 9.3 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF485 LRR_8 PF13855.6 ORY44024.1 - 2e-17 62.7 13.9 7.1e-09 35.3 3.3 2.7 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY44024.1 - 3.7e-12 46.3 34.9 1.3e-05 25.4 5.0 3.8 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY44024.1 - 1.1e-08 34.4 19.2 0.13 12.9 1.9 6.2 5 1 0 5 5 5 4 Leucine Rich Repeat LRR_6 PF13516.6 ORY44024.1 - 6.6e-05 22.6 14.9 0.31 11.2 1.1 4.6 4 0 0 4 4 4 3 Leucine Rich repeat LRR_9 PF14580.6 ORY44024.1 - 0.033 13.7 0.0 0.24 10.9 0.0 2.0 1 1 1 2 2 2 0 Leucine-rich repeat LRR_2 PF07723.13 ORY44024.1 - 0.074 13.7 0.0 54 4.7 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich Repeat Dict-STAT-coil PF09267.10 ORY44024.1 - 0.13 12.7 0.1 1.7 9.0 0.0 2.3 1 1 0 2 2 2 0 Dictyostelium STAT, coiled coil PRK PF00485.18 ORY44025.1 - 5.6e-35 120.9 0.0 6.9e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CoaE PF01121.20 ORY44025.1 - 0.026 14.2 0.2 1.8 8.2 0.1 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_18 PF13238.6 ORY44025.1 - 0.038 14.6 0.1 0.074 13.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain Spore_II_R PF09551.10 ORY44025.1 - 0.17 12.4 0.0 0.53 10.8 0.0 1.7 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) LRR_4 PF12799.7 ORY44026.1 - 0.012 16.0 1.1 0.036 14.5 0.1 2.4 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Zip PF02535.22 ORY44027.1 - 6.3 5.9 8.3 17 4.5 0.0 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter CHD5 PF04420.14 ORY44028.1 - 0.3 10.9 2.1 0.33 10.8 0.8 1.8 2 0 0 2 2 2 0 CHD5-like protein AA_permease_2 PF13520.6 ORY44028.1 - 0.37 9.6 8.5 5.1 5.8 9.1 1.8 1 1 1 2 2 2 0 Amino acid permease Chromate_transp PF02417.15 ORY44028.1 - 0.65 10.1 6.1 0.95 9.6 2.1 2.0 1 1 1 2 2 2 0 Chromate transporter ANF_receptor PF01094.28 ORY44030.1 - 7.7e-18 64.7 0.2 9.1e-18 64.5 0.2 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY44030.1 - 5.4e-06 26.3 0.4 5.4e-06 26.3 0.4 1.4 2 0 0 2 2 2 1 Periplasmic binding protein 7tm_3 PF00003.22 ORY44031.1 - 8.8e-14 51.8 13.3 1.4e-13 51.1 13.3 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 ORY44031.1 - 0.003 16.7 0.0 0.0057 15.8 0.0 1.4 1 0 0 1 1 1 1 Receptor family ligand binding region pPIWI_RE_Z PF18155.1 ORY44031.1 - 0.18 11.7 0.0 0.52 10.2 0.0 1.7 2 0 0 2 2 2 0 pPIWI RE three-gene island domain Z ATP-synt_8 PF00895.20 ORY44032.1 - 0.0037 17.7 0.1 0.007 16.8 0.1 1.5 1 0 0 1 1 1 1 ATP synthase protein 8 ATP19 PF11022.8 ORY44033.1 - 0.074 13.4 0.0 0.1 13.0 0.0 1.2 1 0 0 1 1 1 0 ATP synthase subunit K Lipase_GDSL_2 PF13472.6 ORY44034.1 - 2.1e-13 51.0 0.0 3e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY44034.1 - 0.0012 18.9 0.0 0.003 17.6 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY44035.1 - 1.8e-19 70.9 0.0 2.5e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY44035.1 - 1.3e-11 44.8 0.0 2e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF5055 PF16478.5 ORY44036.1 - 0.0047 17.1 1.7 4.5 7.6 0.2 3.1 2 0 0 2 2 2 2 Domain of unknown function (DUF5055) Tup_N PF08581.10 ORY44036.1 - 0.008 16.5 7.9 0.008 16.5 7.9 7.1 6 2 2 8 8 8 2 Tup N-terminal PKcGMP_CC PF16808.5 ORY44036.1 - 0.0084 15.9 0.3 0.0084 15.9 0.3 9.3 8 1 1 9 9 9 1 Coiled-coil N-terminus of cGMP-dependent protein kinase YgbB PF02542.16 ORY44036.1 - 0.11 12.8 9.3 0.15 12.3 0.1 3.2 3 1 1 4 4 4 0 YgbB family Bacillus_HBL PF05791.11 ORY44036.1 - 0.64 9.8 39.3 0.022 14.6 3.9 5.9 1 1 3 6 6 6 0 Bacillus haemolytic enterotoxin (HBL) YvrJ PF12841.7 ORY44036.1 - 4.4 6.9 12.6 27 4.4 0.1 4.7 4 0 0 4 4 4 0 YvrJ protein family LPP PF04728.13 ORY44036.1 - 6.9 7.2 24.2 4 7.9 0.3 6.4 6 0 0 6 6 6 0 Lipoprotein leucine-zipper HALZ PF02183.18 ORY44037.1 - 0.00041 20.5 22.3 0.087 13.1 4.1 4.7 3 1 1 4 4 4 2 Homeobox associated leucine zipper Leu_zip PF15294.6 ORY44037.1 - 0.0038 16.8 33.0 0.023 14.2 3.5 3.1 1 1 2 3 3 3 2 Leucine zipper TSC22 PF01166.18 ORY44037.1 - 0.032 14.5 14.7 14 6.1 1.9 5.1 5 0 0 5 5 5 0 TSC-22/dip/bun family CASP_C PF08172.12 ORY44037.1 - 0.067 12.5 21.2 0.2 11.0 6.3 3.5 2 1 1 3 3 3 0 CASP C terminal bZIP_1 PF00170.21 ORY44037.1 - 0.16 12.1 28.9 0.086 13.0 7.8 5.8 4 2 1 5 5 5 0 bZIP transcription factor FlaC_arch PF05377.11 ORY44037.1 - 2.5 8.6 20.1 1.1 9.7 0.3 5.0 4 2 1 5 5 5 0 Flagella accessory protein C (FlaC) Tmemb_cc2 PF10267.9 ORY44037.1 - 2.7 7.1 24.0 2.7 7.0 11.3 3.2 1 1 3 4 4 4 0 Predicted transmembrane and coiled-coil 2 protein DivIC PF04977.15 ORY44037.1 - 4.6 7.1 39.1 0.31 10.8 4.2 5.9 5 2 2 7 7 7 0 Septum formation initiator CCDC92 PF14916.6 ORY44037.1 - 5.5 6.8 12.5 8.8 6.2 0.5 4.3 4 0 0 4 4 4 0 Coiled-coil domain of unknown function YabA PF06156.13 ORY44038.1 - 0.0093 16.6 0.6 0.01 16.5 0.6 1.1 1 0 0 1 1 1 1 Initiation control protein YabA CAF20 PF17052.5 ORY44038.1 - 0.027 14.6 0.5 0.033 14.4 0.5 1.1 1 0 0 1 1 1 0 Cap associated factor ZapB PF06005.12 ORY44038.1 - 0.07 13.6 4.0 0.092 13.2 4.0 1.4 1 1 0 1 1 1 0 Cell division protein ZapB TSC22 PF01166.18 ORY44038.1 - 0.071 13.4 0.8 0.14 12.5 0.8 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family bZIP_1 PF00170.21 ORY44038.1 - 0.65 10.1 7.2 0.081 13.0 3.0 1.6 2 0 0 2 2 2 0 bZIP transcription factor DivIC PF04977.15 ORY44038.1 - 1.8 8.4 6.6 5.4 6.9 6.6 1.9 1 1 0 1 1 1 0 Septum formation initiator Golgin_A5 PF09787.9 ORY44039.1 - 2.8e-05 23.7 2.0 3.1e-05 23.6 2.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 GAS PF13851.6 ORY44039.1 - 0.00016 21.1 2.3 0.0025 17.2 0.8 2.1 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding CALCOCO1 PF07888.11 ORY44039.1 - 0.0048 15.8 2.1 0.0055 15.6 2.1 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.11 ORY44039.1 - 0.0098 14.8 0.7 0.011 14.7 0.7 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein HTH_AraC PF00165.23 ORY44039.1 - 0.01 16.0 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family DUF3584 PF12128.8 ORY44039.1 - 0.016 12.7 1.9 0.032 11.8 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.9 ORY44039.1 - 0.033 14.2 1.5 0.033 14.2 1.5 1.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ABC_tran_CTD PF16326.5 ORY44039.1 - 0.035 14.3 0.5 0.035 14.3 0.5 2.0 1 1 0 2 2 2 0 ABC transporter C-terminal domain Mst1_SARAH PF11629.8 ORY44039.1 - 0.04 14.0 1.7 0.16 12.1 0.8 2.2 1 1 1 2 2 2 0 C terminal SARAH domain of Mst1 Fmp27_WPPW PF10359.9 ORY44039.1 - 0.057 12.3 0.9 0.065 12.1 0.9 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Ax_dynein_light PF10211.9 ORY44039.1 - 0.068 13.1 2.6 0.057 13.4 1.1 1.6 1 1 0 1 1 1 0 Axonemal dynein light chain Fez1 PF06818.15 ORY44039.1 - 0.068 13.6 3.0 0.086 13.3 3.0 1.2 1 0 0 1 1 1 0 Fez1 HAP1_N PF04849.13 ORY44039.1 - 0.073 12.3 4.3 0.3 10.3 0.3 2.0 1 1 1 2 2 2 0 HAP1 N-terminal conserved region FapA PF03961.13 ORY44039.1 - 0.08 11.5 0.1 0.081 11.5 0.1 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1161 PF06649.12 ORY44039.1 - 0.082 13.1 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1161) H-kinase_dim PF02895.14 ORY44039.1 - 0.097 13.1 1.0 0.21 12.0 0.9 1.6 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain DUF3145 PF11343.8 ORY44039.1 - 0.098 12.2 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3145) Tup_N PF08581.10 ORY44039.1 - 0.14 12.5 3.4 2.8 8.3 3.6 2.3 1 1 1 2 2 2 0 Tup N-terminal 7tm_6 PF02949.20 ORY44039.1 - 0.17 11.0 0.1 0.2 10.7 0.1 1.1 1 0 0 1 1 1 0 7tm Odorant receptor SOGA PF11365.8 ORY44039.1 - 0.17 13.0 4.4 0.31 12.2 2.0 2.2 1 1 1 2 2 2 0 Protein SOGA DivIC PF04977.15 ORY44039.1 - 0.19 11.5 2.4 3.8 7.4 0.1 2.5 3 0 0 3 3 2 0 Septum formation initiator Apolipoprotein PF01442.18 ORY44039.1 - 0.22 11.4 6.1 0.43 10.4 6.1 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Csm1_N PF18504.1 ORY44039.1 - 0.25 11.7 4.5 0.15 12.4 1.3 2.1 1 1 1 2 2 2 0 Csm1 N-terminal domain WD40_alt PF14077.6 ORY44039.1 - 0.33 10.8 3.3 0.83 9.6 3.3 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif TPR_MLP1_2 PF07926.12 ORY44039.1 - 0.38 10.8 4.8 0.17 12.0 1.2 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 ORY44039.1 - 0.58 10.4 6.1 0.14 12.4 2.7 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Swi5 PF07061.11 ORY44039.1 - 0.61 10.2 4.3 3.1 7.9 2.0 2.7 2 1 0 2 2 2 0 Swi5 Cep57_MT_bd PF06657.13 ORY44039.1 - 0.69 10.4 4.4 0.4 11.2 1.6 2.1 2 1 0 2 2 1 0 Centrosome microtubule-binding domain of Cep57 Pox_A_type_inc PF04508.12 ORY44039.1 - 0.7 9.8 7.1 0.14 12.0 2.0 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat ZapB PF06005.12 ORY44039.1 - 0.92 10.0 9.2 13 6.3 6.2 2.7 1 1 1 2 2 2 0 Cell division protein ZapB APG6_N PF17675.1 ORY44039.1 - 3.4 8.2 8.2 5.8 7.4 7.3 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region RILP PF11461.8 ORY44039.1 - 9.3 6.6 10.7 0.54 10.5 3.9 2.4 2 1 1 3 3 2 0 Rab interacting lysosomal protein Acatn PF13000.7 ORY44040.1 - 2.8e-112 376.0 33.7 3.5e-39 134.7 4.5 4.1 2 1 2 4 4 4 4 Acetyl-coenzyme A transporter 1 DUF4728 PF15860.5 ORY44040.1 - 0.014 16.1 2.6 0.03 15.0 1.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4728) K_trans PF02705.16 ORY44041.1 - 2.9e-149 498.0 25.6 3.5e-149 497.7 25.6 1.1 1 0 0 1 1 1 1 K+ potassium transporter DUF4131 PF13567.6 ORY44041.1 - 0.0025 17.5 4.2 0.85 9.3 1.7 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF4131) Lipase_GDSL_2 PF13472.6 ORY44042.1 - 8.6e-15 55.6 0.0 1.4e-14 54.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY44042.1 - 7.4e-14 52.2 0.0 1.1e-13 51.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY44043.1 - 1.4e-15 58.2 0.0 2e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY44043.1 - 3.3e-14 53.3 0.0 4.6e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY44044.1 - 0.012 16.0 0.0 0.012 16.0 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family LRR_8 PF13855.6 ORY44045.1 - 1e-26 92.5 26.6 3.9e-11 42.6 0.5 4.8 2 1 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 ORY44045.1 - 2.6e-18 65.8 29.8 1.9e-05 24.9 3.2 5.8 2 2 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY44045.1 - 5.4e-10 38.4 35.1 0.052 14.1 0.3 9.6 10 2 1 11 11 11 4 Leucine Rich Repeat LRR_6 PF13516.6 ORY44045.1 - 2.3e-06 27.2 28.6 0.92 9.7 0.4 8.5 8 0 0 8 8 8 5 Leucine Rich repeat F-box PF00646.33 ORY44045.1 - 8.8e-05 22.3 0.8 0.00024 20.9 0.8 1.8 1 0 0 1 1 1 1 F-box domain Lipase_GDSL_2 PF13472.6 ORY44046.1 - 3.1e-32 112.4 0.0 1.9e-15 57.7 0.0 2.6 2 1 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY44046.1 - 6.5e-23 81.8 0.0 3e-11 43.7 0.0 3.0 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase NmrA PF05368.13 ORY44047.1 - 6.8e-20 71.6 0.0 8.9e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 ORY44047.1 - 1.2e-12 48.1 0.0 1.8e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 ORY44047.1 - 3.9e-05 23.9 0.3 0.00017 21.8 0.1 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 ORY44047.1 - 0.00039 20.5 0.0 0.00075 19.6 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.19 ORY44047.1 - 0.0007 18.7 0.1 0.0016 17.5 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY44047.1 - 0.0082 15.6 0.2 0.1 12.0 0.2 2.4 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 ORY44047.1 - 0.018 15.5 0.1 0.032 14.7 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 ORY44047.1 - 0.035 13.3 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein TPR_12 PF13424.6 ORY44048.1 - 8.4e-70 231.1 14.3 5.9e-14 52.1 0.1 6.5 4 1 3 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 ORY44048.1 - 5.2e-69 226.4 1.8 6.2e-11 41.8 0.0 11.2 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 ORY44048.1 - 6.4e-23 79.0 1.7 0.055 13.6 0.0 9.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 ORY44048.1 - 9.7e-23 78.5 8.5 0.0054 16.7 0.1 9.4 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 ORY44048.1 - 1.1e-22 78.9 0.0 0.15 11.9 0.0 10.5 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.6 ORY44048.1 - 1.7e-14 52.7 0.1 2.2 8.7 0.0 8.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY44048.1 - 1.7e-12 47.4 0.7 3.2e-05 23.5 0.1 3.4 1 1 2 3 3 3 3 MalT-like TPR region TPR_19 PF14559.6 ORY44048.1 - 2.6e-10 40.7 5.3 2.5 8.7 0.1 8.2 7 1 2 9 9 9 2 Tetratricopeptide repeat TPR_4 PF07721.14 ORY44048.1 - 1.1e-08 34.9 0.0 7.8 7.5 0.0 7.6 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY44048.1 - 1.4e-08 35.3 3.6 1 10.0 0.0 6.4 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY44048.1 - 2.1e-08 34.3 3.7 7.7 7.6 0.0 8.1 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY44048.1 - 7.7e-06 25.9 4.1 2.3 8.8 0.3 7.4 9 0 0 9 9 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY44048.1 - 0.0025 18.0 0.3 4.5 7.6 0.1 4.7 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 ORY44048.1 - 0.11 13.2 6.1 95 4.0 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat RPN6_N PF18055.1 ORY44048.1 - 0.94 9.9 4.8 5.5 7.4 0.6 3.4 2 2 1 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain Lipase_GDSL_2 PF13472.6 ORY44049.1 - 5.4e-17 62.8 0.0 8.6e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY44049.1 - 5.8e-16 59.1 0.0 6.9e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Imm47 PF15573.6 ORY44049.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 47 CAAP1 PF15335.6 ORY44049.1 - 0.15 12.6 0.3 0.34 11.5 0.3 1.5 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 Pkinase PF00069.25 ORY44050.1 - 3.4e-55 187.3 0.0 1.8e-54 184.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY44050.1 - 5.6e-27 94.6 0.5 2.8e-21 76.0 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY44050.1 - 3.3e-05 23.4 0.0 0.00077 18.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 ORY44050.1 - 6.6e-05 22.4 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY44050.1 - 0.0001 21.4 0.1 0.00013 21.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY44050.1 - 0.0012 18.8 0.2 0.012 15.5 0.2 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_C PF00433.24 ORY44050.1 - 0.0044 17.7 0.0 0.014 16.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase C terminal domain DUF3627 PF12299.8 ORY44050.1 - 0.072 13.2 0.3 2.7 8.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3627) RIO1 PF01163.22 ORY44050.1 - 0.12 12.0 0.0 0.35 10.4 0.0 1.7 1 1 1 2 2 2 0 RIO1 family Lipase_GDSL PF00657.22 ORY44051.1 - 4.2e-20 72.6 0.0 5.6e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY44051.1 - 3.6e-19 69.8 0.0 5.2e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family HIP1_clath_bdg PF16515.5 ORY44052.1 - 0.052 14.1 1.5 0.052 14.1 1.5 3.0 4 0 0 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 UPF0449 PF15136.6 ORY44052.1 - 0.46 11.0 5.0 1.7 9.2 0.8 3.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 FlgN PF05130.12 ORY44052.1 - 0.59 10.6 10.0 3.9 8.0 8.5 2.5 2 1 0 2 2 2 0 FlgN protein Bacillus_HBL PF05791.11 ORY44052.1 - 0.73 9.6 5.5 0.59 9.9 0.2 2.9 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF1664 PF07889.12 ORY44052.1 - 0.94 9.5 12.7 2.6 8.1 0.6 3.1 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 ORY44052.1 - 1.4 9.2 7.7 13 6.1 0.3 3.8 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 ORY44052.1 - 4.8 6.0 13.5 1.2 7.9 9.7 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Med21 PF11221.8 ORY44052.1 - 6 7.1 10.5 0.13 12.5 2.2 2.4 3 0 0 3 3 3 0 Subunit 21 of Mediator complex DUF724 PF05266.14 ORY44052.1 - 8 6.2 13.5 0.58 10.0 7.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) OmpH PF03938.14 ORY44052.1 - 8.6 6.7 10.0 0.68 10.3 4.5 2.0 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Peptidase_S24 PF00717.23 ORY44053.1 - 1.2e-10 41.2 0.1 2.1e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 Peptidase S24-like DEAD PF00270.29 ORY44054.1 - 1.7e-46 158.2 0.0 3e-46 157.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY44054.1 - 1.1e-26 93.4 0.0 2.8e-26 92.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GUCT PF08152.12 ORY44054.1 - 8.9e-21 74.0 0.0 3.8e-20 72.0 0.0 2.1 2 0 0 2 2 2 1 GUCT (NUC152) domain CMS1 PF14617.6 ORY44054.1 - 0.0033 16.8 0.0 0.0033 16.8 0.0 3.4 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit SOBP PF15279.6 ORY44054.1 - 9.3 6.8 8.9 13 6.3 8.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein PIF1 PF05970.14 ORY44055.1 - 1.4e-13 50.8 0.0 1.1e-12 47.8 0.0 2.0 2 0 0 2 2 2 1 PIF1-like helicase Helitron_like_N PF14214.6 ORY44055.1 - 2.5e-11 44.1 0.0 6.9e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus AAA_30 PF13604.6 ORY44055.1 - 4.6e-08 33.0 0.0 9.4e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY44055.1 - 0.00021 21.7 0.0 0.00046 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain zf_C2H2_6 PF18450.1 ORY44055.1 - 0.065 13.0 0.4 0.33 10.7 0.4 2.4 1 0 0 1 1 1 0 Zinc Finger domain AAA_16 PF13191.6 ORY44055.1 - 0.11 12.8 0.1 0.44 10.9 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 ORY44055.1 - 0.14 12.4 0.0 19 5.5 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Histone PF00125.24 ORY44056.1 - 2.5e-17 63.5 0.0 2.8e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORY44056.1 - 2.2e-05 24.5 0.0 2.3e-05 24.5 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 ORY44056.1 - 0.0021 18.3 0.0 0.0026 18.0 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 ORY44056.1 - 0.0038 17.6 0.0 0.0038 17.6 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 ORY44056.1 - 0.061 13.4 0.0 0.066 13.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Pkinase PF00069.25 ORY44058.1 - 6.5e-47 160.1 0.0 3.7e-46 157.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY44058.1 - 1.7e-22 79.9 0.3 1.5e-16 60.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY44058.1 - 1.8e-05 24.2 0.1 0.00054 19.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 ORY44058.1 - 5.5e-05 22.6 0.0 8.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY44058.1 - 0.00014 21.0 0.0 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY44058.1 - 0.0019 18.1 0.2 0.0066 16.4 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_C PF00433.24 ORY44058.1 - 0.0026 18.4 0.0 0.0093 16.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase C terminal domain RIO1 PF01163.22 ORY44058.1 - 0.16 11.5 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF1664 PF07889.12 ORY44059.1 - 0.077 13.0 6.9 2.8 8.0 0.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Peptidase_S24 PF00717.23 ORY44060.1 - 1.2e-10 41.1 0.1 2.3e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase S24-like DEAD PF00270.29 ORY44061.1 - 1.8e-46 158.1 0.0 3e-46 157.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY44061.1 - 1.1e-26 93.4 0.0 2.8e-26 92.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GUCT PF08152.12 ORY44061.1 - 9.1e-21 74.0 0.0 3.8e-20 72.0 0.0 2.1 2 0 0 2 2 2 1 GUCT (NUC152) domain CMS1 PF14617.6 ORY44061.1 - 0.0033 16.8 0.0 0.0033 16.8 0.0 3.4 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit RabGAP-TBC PF00566.18 ORY44064.1 - 9.2e-54 182.3 0.1 1.2e-53 182.0 0.1 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain NDK PF00334.19 ORY44065.1 - 9.7e-56 187.5 0.0 2.8e-28 98.6 0.0 2.2 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 ORY44065.1 - 3.8e-06 26.7 0.4 6.6e-05 22.7 0.2 2.4 2 0 0 2 2 2 1 DUF1126 PH-like domain LMP PF04778.12 ORY44065.1 - 0.02 14.8 0.0 0.35 10.8 0.0 2.4 2 0 0 2 2 2 0 LMP repeated region GPP34 PF05719.11 ORY44066.1 - 1.4e-49 168.9 0.4 2.6e-49 168.0 0.4 1.4 1 1 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) NOA36 PF06524.12 ORY44066.1 - 7.3 5.8 6.9 10 5.3 6.9 1.2 1 0 0 1 1 1 0 NOA36 protein ARPC4 PF05856.12 ORY44067.1 - 2.7e-80 267.8 8.0 3e-80 267.7 8.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Sm_like PF16243.5 ORY44067.1 - 0.013 15.6 0.1 0.023 14.9 0.1 1.4 1 0 0 1 1 1 0 Sm_like domain GPS2_interact PF15784.5 ORY44067.1 - 0.14 12.6 2.8 7.4 7.1 0.1 2.2 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain DUF3467 PF11950.8 ORY44067.1 - 0.15 12.3 0.5 0.78 10.0 0.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3467) RNA_helicase PF00910.22 ORY44068.1 - 0.0085 16.5 0.2 0.11 12.9 0.1 2.2 1 1 1 2 2 2 1 RNA helicase GSK-3_bind PF05350.12 ORY44069.1 - 0.071 12.4 0.1 0.085 12.2 0.1 1.1 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding Semialdhyde_dhC PF02774.18 ORY44071.1 - 4.9e-34 118.0 0.0 7.6e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 ORY44071.1 - 3.7e-26 91.9 0.1 6.4e-26 91.2 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 ORY44071.1 - 0.00052 20.3 0.3 0.0013 19.0 0.2 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 ORY44071.1 - 0.0069 16.5 0.3 0.013 15.6 0.3 1.5 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Gp_dh_C PF02800.20 ORY44071.1 - 0.02 14.5 0.0 0.042 13.4 0.0 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain NAD_binding_10 PF13460.6 ORY44071.1 - 0.34 10.8 1.6 0.71 9.7 1.6 1.6 1 1 0 1 1 1 0 NAD(P)H-binding Ribosomal_L39 PF00832.20 ORY44072.1 - 6.7e-22 76.9 11.1 7.7e-22 76.7 11.1 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Patatin PF01734.22 ORY44078.1 - 8.1e-19 68.6 1.6 4e-18 66.3 1.6 2.2 1 1 0 1 1 1 1 Patatin-like phospholipase cNMP_binding PF00027.29 ORY44078.1 - 5.6e-11 42.4 0.0 5.5e-09 36.0 0.0 2.8 2 1 0 2 2 2 1 Cyclic nucleotide-binding domain HisKA_4TM PF16926.5 ORY44079.1 - 0.075 12.6 3.4 0.13 11.8 3.4 1.3 1 0 0 1 1 1 0 Archaeal 4TM region of histidine kinase Transmemb_17 PF09799.9 ORY44080.1 - 6.2e-09 36.4 2.6 6.6e-09 36.3 2.6 1.0 1 0 0 1 1 1 1 Predicted membrane protein DUF640 PF04852.12 ORY44081.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF640) Lipase_GDSL_2 PF13472.6 ORY44085.1 - 3.9e-40 138.1 0.0 1.9e-19 70.8 0.0 2.2 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY44085.1 - 9.3e-28 97.6 0.0 2.6e-13 50.4 0.0 2.4 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase DUF1016_N PF17761.1 ORY44085.1 - 0.02 15.0 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 DUF1016 N-terminal domain DUF4042 PF13251.6 ORY44085.1 - 0.049 13.3 0.0 11 5.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) CRAL_TRIO PF00650.20 ORY44086.1 - 5.6e-06 26.2 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain UBA_4 PF14555.6 ORY44086.1 - 0.00014 21.6 0.6 0.00065 19.5 0.6 2.0 2 0 0 2 2 2 1 UBA-like domain Dsl1_N PF11988.8 ORY44086.1 - 0.14 11.1 1.9 0.26 10.2 0.2 2.0 2 0 0 2 2 2 0 Retrograde transport protein Dsl1 N terminal EPO_TPO PF00758.18 ORY44087.1 - 0.16 12.0 1.8 1.7 8.6 0.0 2.6 2 1 0 2 2 2 0 Erythropoietin/thrombopoietin CAP_N PF01213.19 ORY44087.1 - 0.31 10.5 6.5 0.54 9.7 6.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 ORY44087.1 - 5.8 7.0 9.1 13 5.8 9.1 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Ank_2 PF12796.7 ORY44088.1 - 1.9e-28 98.9 8.5 1.2e-11 45.0 0.4 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY44088.1 - 1.5e-11 43.5 4.4 0.3 11.8 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 ORY44088.1 - 8e-11 42.3 0.9 3e-05 24.5 0.3 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY44088.1 - 4.3e-09 36.5 5.3 0.013 15.8 0.0 4.7 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY44088.1 - 2.4e-06 27.7 3.7 0.76 10.3 0.0 5.2 4 1 1 5 5 5 2 Ankyrin repeat CstA_5TM PF13722.6 ORY44088.1 - 0.042 14.2 0.4 0.074 13.4 0.4 1.4 1 0 0 1 1 1 0 5TM C-terminal transporter carbon starvation CstA HECT PF00632.25 ORY44089.1 - 1.4e-98 330.2 0.1 2.6e-98 329.3 0.1 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 ORY44089.1 - 4.3e-83 279.3 0.0 4.3e-83 279.3 0.0 4.4 4 1 0 4 4 4 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 ORY44089.1 - 2.4e-55 188.4 0.5 1.5e-54 185.8 0.0 2.5 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) UBM PF14377.6 ORY44089.1 - 4.8e-26 89.4 22.1 1.2e-10 40.5 2.5 4.6 5 0 0 5 5 5 3 Ubiquitin binding region UBA PF00627.31 ORY44089.1 - 6.7e-09 35.5 0.0 1.9e-08 34.0 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain MAP7 PF05672.11 ORY44089.1 - 0.042 13.5 33.9 0.15 11.8 33.9 1.9 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family UIM PF02809.20 ORY44089.1 - 0.17 11.8 3.3 1.5 8.9 3.3 2.8 1 0 0 1 1 1 0 Ubiquitin interaction motif NARP1 PF12569.8 ORY44089.1 - 3.1 6.6 13.3 5.8 5.7 13.3 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 p450 PF00067.22 ORY44090.1 - 2.8e-95 319.8 0.0 3.7e-95 319.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.20 ORY44090.1 - 7.4e-29 100.9 0.1 2.1e-27 96.1 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 ORY44090.1 - 1.5e-21 77.1 0.0 4.2e-21 75.7 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ORY44090.1 - 5.1e-17 62.5 0.0 1.9e-16 60.6 0.0 2.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain HTH_Tnp_1 PF01527.20 ORY44092.1 - 0.00063 20.0 1.0 0.0013 19.0 0.0 2.1 2 0 0 2 2 2 1 Transposase HTH_28 PF13518.6 ORY44092.1 - 0.001 19.1 0.2 0.001 19.1 0.2 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain DDE_1 PF03184.19 ORY44092.1 - 0.0011 18.6 0.2 0.024 14.3 0.1 2.3 1 1 1 2 2 2 1 DDE superfamily endonuclease CoA_binding_3 PF13727.6 ORY44092.1 - 0.0074 16.3 0.2 0.013 15.5 0.2 1.4 1 0 0 1 1 1 1 CoA-binding domain BrkDBD PF09607.10 ORY44092.1 - 0.0094 15.7 0.0 0.03 14.1 0.0 1.8 1 0 0 1 1 1 1 Brinker DNA-binding domain HTH_Tnp_ISL3 PF13542.6 ORY44092.1 - 0.01 15.2 0.2 5 6.6 0.2 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DDE_3 PF13358.6 ORY44092.1 - 0.034 13.9 0.4 2.3 7.9 0.1 2.2 1 1 1 2 2 2 0 DDE superfamily endonuclease HTH_29 PF13551.6 ORY44092.1 - 0.078 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_23 PF13384.6 ORY44092.1 - 0.17 11.7 1.9 0.26 11.1 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain Cwf_Cwc_15 PF04889.12 ORY44093.1 - 0.027 14.2 4.8 0.035 13.8 4.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 ORY44093.1 - 0.21 12.0 7.2 0.34 11.3 7.2 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 ORY44093.1 - 2.4 7.4 6.9 3 7.1 6.9 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 ORY44093.1 - 3.9 7.9 8.5 2.2 8.7 6.5 1.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GST_N_3 PF13417.6 ORY44094.1 - 4.2e-16 59.1 0.1 7.1e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY44094.1 - 3.3e-12 46.6 0.1 5.7e-12 45.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY44094.1 - 8.3e-12 45.2 0.0 1.5e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY44094.1 - 1.1e-07 32.0 0.0 5.6e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY44094.1 - 1.2e-05 25.4 0.0 1.9e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY44094.1 - 0.0036 17.3 0.0 0.0076 16.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 ORY44094.1 - 0.032 15.0 0.0 0.11 13.3 0.0 2.1 1 1 1 2 2 2 0 Glutathione S-transferase N-terminal domain GnsAB_toxin PF08178.11 ORY44094.1 - 0.041 13.8 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system Creatinase_N_2 PF16189.5 ORY44096.1 - 7.7e-48 162.6 0.0 9.1e-47 159.1 0.0 2.3 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 ORY44096.1 - 8.2e-41 140.0 0.0 1.3e-40 139.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 ORY44096.1 - 8.7e-24 83.4 0.2 2.9e-23 81.7 0.2 2.0 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 ORY44096.1 - 3.6e-19 69.7 0.0 1.5e-16 61.2 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain HNH_2 PF13391.6 ORY44097.1 - 0.00017 21.6 0.1 0.00037 20.6 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease Alpha_kinase PF02816.18 ORY44098.1 - 3.9e-15 56.4 0.0 7.1e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Alpha-kinase family GTP_EFTU PF00009.27 ORY44099.1 - 6.5e-48 162.9 0.0 1e-47 162.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 ORY44099.1 - 3e-26 91.6 0.0 6.2e-26 90.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFTUD2 PF16004.5 ORY44099.1 - 3.7e-24 85.6 0.4 6.9e-24 84.8 0.4 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_C PF00679.24 ORY44099.1 - 1.7e-23 82.5 0.0 9.1e-23 80.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 ORY44099.1 - 6.4e-10 39.3 0.3 1.9e-09 37.8 0.3 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 ORY44099.1 - 2.9e-07 30.5 0.0 7.3e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 ORY44099.1 - 4.4e-07 30.0 0.0 1e-06 28.8 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 ORY44099.1 - 0.02 14.5 0.0 0.053 13.1 0.0 1.6 1 1 0 1 1 1 0 Ras family Roc PF08477.13 ORY44099.1 - 0.074 13.3 0.0 0.38 11.0 0.0 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PG_binding_4 PF12229.8 ORY44099.1 - 0.14 12.5 0.0 0.43 10.9 0.0 1.8 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Gp45_2 PF17470.2 ORY44101.1 - 0.1 12.6 0.5 1.3 9.0 0.1 2.5 2 0 0 2 2 2 0 Phage gene product 45.2 SRP-alpha_N PF04086.13 ORY44101.1 - 0.17 11.8 16.8 0.33 10.8 9.0 2.4 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal Kinesin PF00225.23 ORY44103.1 - 6.1e-110 367.3 0.7 6.1e-110 367.3 0.7 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ORY44103.1 - 2.1e-24 86.2 0.1 2.1e-24 86.2 0.1 2.4 3 0 0 3 3 3 1 Microtubule binding KfrA_N PF11740.8 ORY44103.1 - 0.014 16.0 3.4 0.014 16.0 3.4 2.6 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF1284 PF06935.11 ORY44103.1 - 0.029 14.8 0.4 0.12 12.9 0.4 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1284) DUF4140 PF13600.6 ORY44103.1 - 0.13 12.8 4.7 1 9.9 2.2 3.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3053 PF11254.8 ORY44103.1 - 7.4 6.1 11.2 3.1 7.3 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) Roughex PF06020.11 ORY44104.1 - 0.23 10.5 3.3 0.29 10.2 3.3 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Afaf PF15339.6 ORY44105.1 - 0.0083 15.9 0.2 0.0089 15.8 0.2 1.0 1 0 0 1 1 1 1 Acrosome formation-associated factor Orf78 PF06024.12 ORY44105.1 - 0.033 14.5 0.3 0.038 14.3 0.3 1.0 1 0 0 1 1 1 0 Orf78 (ac78) Glt_symporter PF03616.14 ORY44105.1 - 0.085 11.5 0.1 0.082 11.6 0.1 1.0 1 0 0 1 1 1 0 Sodium/glutamate symporter ESP PF16590.5 ORY44105.1 - 0.088 13.1 0.1 0.1 12.9 0.1 1.1 1 0 0 1 1 1 0 Exocrine gland-secreting peptide DUF5516 PF17637.2 ORY44105.1 - 0.16 11.7 0.9 0.23 11.2 0.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5516) FAM60A PF15396.6 ORY44106.1 - 0.027 14.5 0.0 0.029 14.4 0.0 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Creatinase_N_2 PF16189.5 ORY44107.1 - 3.6e-50 170.2 0.0 1.4e-49 168.3 0.0 1.9 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 ORY44107.1 - 3.9e-45 154.1 0.1 6.2e-45 153.5 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 ORY44107.1 - 1.2e-23 82.9 0.1 3.8e-23 81.3 0.1 1.9 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 ORY44107.1 - 2.2e-22 80.1 0.0 4.1e-17 63.1 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain ACT_7 PF13840.6 ORY44108.1 - 5.7e-20 70.9 0.1 9.9e-20 70.1 0.1 1.4 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 ORY44108.1 - 0.038 13.8 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 ACT domain Castor1_N PF18700.1 ORY44108.1 - 0.16 11.8 0.6 0.38 10.6 0.0 2.0 3 0 0 3 3 3 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain Mt_ATP-synt_B PF05405.14 ORY44109.1 - 6.3e-36 123.5 0.9 7.4e-36 123.2 0.9 1.0 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2764 PF10962.8 ORY44109.1 - 0.022 14.2 0.1 0.027 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) Ribosomal_S26e PF01283.19 ORY44110.1 - 4.8e-27 94.5 0.9 5.4e-27 94.4 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Dus PF01207.17 ORY44112.1 - 1.9e-34 119.2 0.0 2.1e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) IMPDH PF00478.25 ORY44112.1 - 0.027 13.5 0.0 0.036 13.1 0.0 1.3 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain DUF3509 PF12021.8 ORY44112.1 - 0.091 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3509) FMN_dh PF01070.18 ORY44112.1 - 0.11 11.5 0.0 0.28 10.2 0.0 1.6 1 1 1 2 2 2 0 FMN-dependent dehydrogenase Saf_2TM PF18303.1 ORY44113.1 - 0.19 11.3 3.8 0.25 10.9 3.0 1.5 1 1 0 1 1 1 0 SAVED-fused 2TM effector domain zf-C4H2 PF10146.9 ORY44114.1 - 0.23 11.8 1.0 0.34 11.2 0.7 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein Sugar_tr PF00083.24 ORY44115.1 - 2.3e-49 168.5 21.4 2.9e-49 168.2 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY44115.1 - 3.2e-23 82.2 31.1 6.5e-16 58.2 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORY44115.1 - 2.5e-05 23.8 5.6 6.3e-05 22.4 5.6 1.6 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB UCH PF00443.29 ORY44117.1 - 1.1e-32 113.5 0.0 2.1e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY44117.1 - 9.2e-18 64.9 2.6 6.4e-09 35.8 0.0 3.6 2 2 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 ORY44117.1 - 1.3e-08 35.3 1.1 1.2e-06 29.1 0.1 3.4 3 0 0 3 3 3 1 DUSP domain zf-RanBP PF00641.18 ORY44117.1 - 3.4e-06 26.3 4.1 3.4e-06 26.3 4.1 3.5 4 0 0 4 4 4 1 Zn-finger in Ran binding protein and others ubiquitin PF00240.23 ORY44117.1 - 7.5e-05 22.4 0.1 0.00018 21.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family UIM PF02809.20 ORY44117.1 - 0.0048 16.7 1.8 0.013 15.3 1.8 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif SBF PF01758.16 ORY44118.1 - 5.9e-42 143.6 9.3 1.2e-41 142.6 9.3 1.5 1 0 0 1 1 1 1 Sodium Bile acid symporter family MCH PF02289.16 ORY44118.1 - 0.13 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Cyclohydrolase (MCH) Corona_NS3b PF03053.14 ORY44118.1 - 0.52 10.0 4.3 12 5.6 0.1 2.4 2 0 0 2 2 2 0 ORF3b coronavirus protein ABC2_membrane PF01061.24 ORY44120.1 - 5.3e-38 130.6 16.4 5.3e-38 130.6 16.4 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 ORY44120.1 - 8e-14 52.3 0.0 1.5e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 ORY44120.1 - 1e-05 24.8 14.4 1e-05 24.8 14.4 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein LacI PF00356.21 ORY44120.1 - 0.077 12.8 0.2 0.19 11.6 0.2 1.7 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family AAA_21 PF13304.6 ORY44120.1 - 0.081 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Ni_hydr_CYTB PF01292.20 ORY44120.1 - 0.35 10.4 3.4 1.1 8.9 0.5 2.5 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 SAM_1 PF00536.30 ORY44121.1 - 0.011 16.1 0.4 0.031 14.7 0.4 1.7 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 ORY44121.1 - 0.014 15.4 0.2 0.045 13.7 0.2 1.8 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain PTP_tm PF18861.1 ORY44121.1 - 0.13 12.3 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J SKG6 PF08693.10 ORY44121.1 - 0.16 11.4 3.4 0.28 10.6 3.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain WD40 PF00400.32 ORY44122.1 - 5.1e-41 137.9 27.3 2.4e-07 31.3 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY44122.1 - 4.4e-08 33.3 1.8 1.3 9.4 0.0 5.0 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY44122.1 - 1.8e-07 30.2 8.1 1.3 7.5 0.2 5.4 3 3 3 6 6 6 5 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY44122.1 - 0.00023 20.6 0.4 0.62 9.3 0.0 3.1 2 1 1 3 3 3 2 WD40-like domain PQQ_2 PF13360.6 ORY44122.1 - 0.005 16.4 0.5 0.16 11.5 0.0 2.7 1 1 2 3 3 3 2 PQQ-like domain DUF5046 PF16465.5 ORY44122.1 - 0.0051 16.3 0.0 3.1 7.2 0.0 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF5046) GST_N_3 PF13417.6 ORY44126.1 - 1.7e-17 63.6 0.0 2.8e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY44126.1 - 2.6e-17 62.9 0.0 4.3e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY44126.1 - 3.4e-12 46.5 0.0 5.4e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY44126.1 - 5.2e-08 33.0 0.0 2e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY44126.1 - 2.4e-06 27.7 0.0 4.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY44126.1 - 0.00012 22.0 0.0 0.00031 20.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 ORY44126.1 - 0.055 13.7 0.0 0.25 11.6 0.0 2.1 3 0 0 3 3 3 0 Glutaredoxin Cadherin_C_2 PF16492.5 ORY44127.1 - 0.012 16.4 0.3 0.029 15.1 0.2 1.9 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal NPV_P10 PF05531.12 ORY44127.1 - 0.16 12.4 2.4 1.6 9.3 0.3 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Striatin PF08232.12 ORY44127.1 - 0.41 11.2 11.8 1.8 9.1 5.9 2.7 1 1 1 2 2 2 0 Striatin family DUF1664 PF07889.12 ORY44127.1 - 0.94 9.5 14.7 0.096 12.7 1.6 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 ORY44127.1 - 1.4 9.1 16.3 0.88 9.8 1.1 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF641 PF04859.12 ORY44127.1 - 2.5 8.4 12.2 2.8 8.3 0.4 3.5 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) GIT_CC PF16559.5 ORY44127.1 - 9.9 6.1 11.2 0.86 9.5 0.1 3.9 5 0 0 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF1769 PF08588.10 ORY44128.1 - 4.7e-10 39.5 0.0 8.8e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) CN_hydrolase PF00795.22 ORY44129.1 - 1.2e-42 146.1 0.0 1.3e-42 145.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase JHY PF15261.6 ORY44133.1 - 0.089 13.5 5.1 0.15 12.8 5.1 1.4 1 0 0 1 1 1 0 Jhy protein SR-25 PF10500.9 ORY44133.1 - 0.21 11.1 8.9 0.23 11.0 8.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAM220 PF15487.6 ORY44133.1 - 0.47 10.0 6.4 0.59 9.7 6.4 1.2 1 0 0 1 1 1 0 FAM220 family DUF4680 PF15730.5 ORY44133.1 - 0.84 10.0 8.7 1.1 9.6 8.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) Hamartin PF04388.12 ORY44133.1 - 2.7 6.6 8.0 2.7 6.5 8.0 1.0 1 0 0 1 1 1 0 Hamartin protein Kinesin PF00225.23 ORY44134.1 - 3e-37 128.3 0.4 1.8e-35 122.5 0.4 2.1 1 1 0 1 1 1 1 Kinesin motor domain SAM_PNT PF02198.16 ORY44134.1 - 0.011 15.7 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain FAD-SLDH PF12318.8 ORY44135.1 - 3.3 7.7 7.1 0.62 10.1 1.2 2.0 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase PXA PF02194.15 ORY44135.1 - 5.8 6.9 10.3 25 4.8 10.3 1.8 1 1 0 1 1 1 0 PXA domain DUF3619 PF12279.8 ORY44135.1 - 6 7.2 9.5 0.71 10.2 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3619) KH_1 PF00013.29 ORY44137.1 - 6.7e-44 147.6 11.2 2.2e-18 65.8 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 ORY44137.1 - 1.6e-09 37.4 7.2 0.022 14.6 0.2 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 ORY44137.1 - 3.7e-09 36.3 0.5 0.78 9.7 0.0 4.3 4 0 0 4 4 4 4 KH domain KH_5 PF13184.6 ORY44137.1 - 0.006 16.6 10.2 2 8.6 0.1 4.2 3 1 1 4 4 4 2 NusA-like KH domain TMV_coat PF00721.21 ORY44137.1 - 9.2 6.1 7.4 18 5.1 3.2 2.5 2 0 0 2 2 2 0 Virus coat protein (TMV like) Cadherin_C_2 PF16492.5 ORY44138.1 - 2 9.2 12.5 2.1 9.2 7.8 3.0 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal Cadherin_C_2 PF16492.5 ORY44140.1 - 0.018 15.8 7.5 0.092 13.5 7.5 2.0 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal DUF1129 PF06570.11 ORY44140.1 - 0.14 11.6 1.8 0.19 11.2 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Sec1 PF00995.23 ORY44141.1 - 5.6e-92 309.8 0.2 7e-91 306.2 0.2 2.1 1 1 0 1 1 1 1 Sec1 family Glyco_hydro_18 PF00704.28 ORY44142.1 - 5e-59 200.6 1.4 5.6e-59 200.4 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DHHC PF01529.20 ORY44144.1 - 1.2 9.2 6.8 2.8 8.1 6.8 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase cNMP_binding PF00027.29 ORY44146.1 - 8.9e-15 54.5 0.0 1.7e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain MFS_1 PF07690.16 ORY44147.1 - 1.9e-42 145.5 44.1 1.6e-26 93.1 14.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORY44147.1 - 1e-05 25.0 20.2 0.0012 18.2 6.7 2.8 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 ORY44147.1 - 1.6e-05 23.4 9.5 2.7e-05 22.7 0.5 2.8 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 ORY44147.1 - 0.046 12.6 25.6 0.049 12.5 5.4 3.0 2 2 1 3 3 3 0 Sugar (and other) transporter DUF4271 PF14093.6 ORY44147.1 - 3.8 7.4 14.4 1.7 8.5 5.2 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4271) MFS_1 PF07690.16 ORY44148.1 - 9.5e-55 185.9 38.6 8.2e-36 123.6 7.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORY44148.1 - 7.4e-11 41.9 27.8 3.8e-06 26.4 10.0 2.5 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 ORY44148.1 - 1.2e-10 40.9 30.9 1.4e-08 34.0 31.1 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter DUF3149 PF11346.8 ORY44148.1 - 4.5 7.0 8.9 5.4 6.7 1.3 3.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) MFS_1 PF07690.16 ORY44149.1 - 1.1e-34 120.0 44.0 2.4e-26 92.5 22.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORY44149.1 - 4e-06 26.4 20.2 8.3e-06 25.3 20.2 1.5 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 ORY44149.1 - 0.00032 19.7 6.0 0.00032 19.7 6.0 2.3 2 1 0 2 2 2 2 MFS_1 like family MOSP_C PF02722.15 ORY44149.1 - 0.064 12.9 0.1 0.09 12.4 0.1 1.2 1 0 0 1 1 1 0 Major Outer Sheath Protein C-terminal domain Mito_carr PF00153.27 ORY44150.1 - 2.1e-07 30.7 0.1 3.5e-06 26.8 0.1 2.1 1 1 0 1 1 1 1 Mitochondrial carrier protein Mito_carr PF00153.27 ORY44151.1 - 9.9e-24 83.1 2.9 1.7e-18 66.3 0.7 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein LRR_8 PF13855.6 ORY44152.1 - 3.3e-06 26.8 15.3 0.0011 18.7 1.6 3.4 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 ORY44152.1 - 0.0037 17.7 20.3 0.039 14.4 1.1 4.3 1 1 4 5 5 5 3 Leucine Rich repeats (2 copies) DUF1218 PF06749.12 ORY44152.1 - 0.24 12.0 1.8 0.91 10.1 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1218) Renin_r PF07850.14 ORY44152.1 - 0.3 11.7 2.0 0.63 10.7 0.1 2.3 2 0 0 2 2 2 0 Renin receptor-like protein PA28_beta PF02252.18 ORY44153.1 - 2.4e-10 40.3 0.0 6.5e-09 35.6 0.0 2.1 1 1 0 1 1 1 1 Proteasome activator pa28 beta subunit LRR_4 PF12799.7 ORY44154.1 - 6.2e-10 39.2 18.0 2.1e-05 24.8 1.4 3.1 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY44154.1 - 1.1e-09 37.9 12.4 2.5e-06 27.1 3.5 3.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 ORY44154.1 - 1.2e-05 25.2 10.1 0.92 10.3 0.0 5.2 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 ORY44154.1 - 0.00072 19.4 9.3 8.4 6.7 0.6 4.6 4 0 0 4 4 4 2 Leucine Rich repeat OAD_gamma PF04277.13 ORY44154.1 - 0.87 10.2 3.8 2.5 8.8 0.0 2.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain LRR19-TM PF15176.6 ORY44154.1 - 3.7 7.6 4.1 3.8 7.6 0.0 2.4 2 1 0 2 2 2 0 Leucine-rich repeat family 19 TM domain LRR_8 PF13855.6 ORY44155.1 - 2.1e-10 40.2 9.0 0.0023 17.7 0.3 3.4 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY44155.1 - 4e-06 27.1 11.2 0.026 14.9 6.1 3.0 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY44155.1 - 0.01 16.3 8.2 8.6 7.4 0.5 5.1 3 1 1 4 4 4 0 Leucine Rich Repeat 7TM_GPCR_Sri PF10327.9 ORY44155.1 - 0.012 14.8 3.2 0.019 14.2 3.2 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sri LRR_8 PF13855.6 ORY44157.1 - 7.7e-11 41.6 5.6 1.9e-09 37.1 3.0 2.4 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 ORY44157.1 - 8e-11 42.0 11.0 6.6e-07 29.5 1.8 3.4 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY44157.1 - 2e-05 24.5 1.0 0.29 11.8 0.0 4.0 3 0 0 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.6 ORY44157.1 - 0.0059 16.6 6.8 0.7 10.1 0.6 3.9 4 0 0 4 4 4 2 Leucine Rich repeat DoxA PF07680.11 ORY44157.1 - 0.046 13.6 0.4 2.2 8.2 0.0 2.4 1 1 0 2 2 2 0 TQO small subunit DoxA Cation_ATPase_C PF00689.21 ORY44157.1 - 0.24 11.1 11.7 0.14 11.8 9.9 1.4 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus DHHC PF01529.20 ORY44157.1 - 9.5 6.3 15.2 2e+02 2.0 15.2 2.2 1 1 0 1 1 1 0 DHHC palmitoyltransferase MRC1 PF09444.10 ORY44158.1 - 3.7e-12 47.0 0.8 3.7e-12 47.0 0.8 3.2 3 1 0 3 3 3 1 MRC1-like domain DUF4196 PF13846.6 ORY44158.1 - 0.00046 20.4 7.5 0.00046 20.4 7.5 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4196) 7tm_1 PF00001.21 ORY44159.1 - 0.0027 17.1 5.2 0.0027 17.1 5.2 1.9 1 1 1 2 2 2 2 7 transmembrane receptor (rhodopsin family) Bax1-I PF01027.20 ORY44159.1 - 0.1 12.4 7.9 0.93 9.3 7.7 2.0 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Beta-lactamase PF00144.24 ORY44160.1 - 7.5e-09 35.3 0.0 1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase ABC1 PF03109.16 ORY44161.1 - 1.2e-21 77.1 1.5 8.6e-19 67.9 0.3 2.6 1 1 1 2 2 2 2 ABC1 family Beta-lactamase PF00144.24 ORY44161.1 - 1e-06 28.2 0.1 1.5e-05 24.4 0.1 2.1 1 1 0 1 1 1 1 Beta-lactamase DUF5345 PF17280.2 ORY44162.1 - 0.012 15.6 0.3 0.03 14.3 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5345) 7tm_1 PF00001.21 ORY44163.1 - 2.1e-09 37.1 0.6 2.5e-09 36.8 0.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srv PF10323.9 ORY44163.1 - 0.00057 19.3 0.2 0.00069 19.1 0.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF126 PF01989.16 ORY44163.1 - 0.039 13.7 0.1 0.25 11.1 0.1 2.1 2 0 0 2 2 2 0 Aconitase X swivel domain DUF4244 PF14029.6 ORY44163.1 - 0.11 11.9 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) S1FA PF04689.13 ORY44165.1 - 0.33 11.1 0.2 0.33 11.1 0.2 2.2 3 0 0 3 3 3 0 DNA binding protein S1FA NAM-associated PF14303.6 ORY44166.1 - 5e-13 50.1 1.8 7e-13 49.6 1.8 1.2 1 0 0 1 1 1 1 No apical meristem-associated C-terminal domain MSA-2c PF12238.8 ORY44166.1 - 0.0076 16.3 2.6 0.012 15.7 2.6 1.3 1 0 0 1 1 1 1 Merozoite surface antigen 2c Zn_clus PF00172.18 ORY44169.1 - 5e-07 29.7 9.9 9.6e-07 28.8 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY44169.1 - 8.8e-07 28.2 0.1 1.2e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RNA_helicase PF00910.22 ORY44170.1 - 0.072 13.5 0.3 0.71 10.3 0.2 2.2 1 1 1 2 2 2 0 RNA helicase CtsR_C PF17727.1 ORY44170.1 - 0.51 10.5 2.8 8.9 6.5 1.1 2.5 2 0 0 2 2 2 0 CtsR C-terminal dimerization domain DUF5089 PF17002.5 ORY44171.1 - 3.5e-05 23.8 0.9 5.1e-05 23.2 0.7 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF5089) V-SNARE_C PF12352.8 ORY44171.1 - 0.00054 20.2 1.1 0.019 15.2 0.2 2.9 3 1 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus DUF1664 PF07889.12 ORY44171.1 - 0.0011 19.0 4.8 0.83 9.7 0.1 2.8 2 1 1 3 3 3 3 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 ORY44171.1 - 0.027 14.8 3.5 0.065 13.5 1.9 2.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Snapin_Pallidin PF14712.6 ORY44171.1 - 0.037 14.4 4.2 3.7 8.0 2.5 2.7 3 0 0 3 3 3 0 Snapin/Pallidin FlaC_arch PF05377.11 ORY44171.1 - 0.12 12.8 1.7 3.4 8.1 0.2 2.9 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 ORY44171.1 - 0.26 11.8 6.6 13 6.3 0.5 3.8 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein PMEI PF04043.15 ORY44171.1 - 0.57 10.5 7.5 35 4.7 7.5 2.1 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor FAM72 PF14976.6 ORY44172.1 - 1.4e-55 187.4 6.1 2.1e-55 186.8 6.1 1.2 1 0 0 1 1 1 1 FAM72 protein FliJ PF02050.16 ORY44172.1 - 5.2 7.3 6.4 3.6 7.8 3.1 2.1 1 1 1 2 2 2 0 Flagellar FliJ protein Myb_DNA-binding PF00249.31 ORY44173.1 - 0.08 13.2 2.3 6.6 7.0 0.1 3.3 2 2 0 2 2 2 0 Myb-like DNA-binding domain Zn_clus PF00172.18 ORY44176.1 - 1.1e-07 31.8 9.9 1.9e-07 31.1 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADIP PF11559.8 ORY44177.1 - 0.043 13.9 0.5 0.071 13.2 0.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding 7tm_1 PF00001.21 ORY44178.1 - 2.4e-12 46.8 11.7 3e-12 46.4 11.7 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Jnk-SapK_ap_N PF09744.9 ORY44179.1 - 0.013 15.7 5.4 0.016 15.4 5.4 1.1 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 HSBP1 PF06825.12 ORY44179.1 - 0.042 13.7 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 DUF3347 PF11827.8 ORY44179.1 - 0.099 12.8 0.4 0.12 12.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Fib_alpha PF08702.10 ORY44179.1 - 0.13 12.4 1.0 0.17 12.1 1.0 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family HTH_17 PF12728.7 ORY44180.1 - 0.028 14.6 0.3 0.11 12.7 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain RGS PF00615.19 ORY44181.1 - 2.1e-14 53.8 0.5 5.7e-14 52.4 0.1 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain FERM_N PF09379.10 ORY44181.1 - 0.0067 16.3 0.2 0.024 14.5 0.2 1.9 1 0 0 1 1 1 1 FERM N-terminal domain DNA_pol_P_Exo PF18049.1 ORY44181.1 - 0.032 13.6 0.1 0.07 12.5 0.1 1.6 1 0 0 1 1 1 0 DNA polymerase nu pseudo-exo MscL PF01741.18 ORY44182.1 - 1.2e-31 109.5 0.2 1.7e-31 109.0 0.2 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL Chal_sti_synt_C PF02797.15 ORY44182.1 - 0.00055 19.9 0.0 0.00077 19.5 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain GPDPase_memb PF10110.9 ORY44182.1 - 0.012 14.4 0.1 0.02 13.7 0.1 1.3 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase Herpes_U30 PF04523.13 ORY44182.1 - 0.051 11.5 0.1 0.059 11.2 0.1 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 MscL PF01741.18 ORY44183.1 - 2.7e-17 63.2 0.2 3.6e-17 62.8 0.2 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL FAM76 PF16046.5 ORY44183.1 - 0.043 13.2 0.9 0.057 12.8 0.9 1.1 1 0 0 1 1 1 0 FAM76 protein C1_1 PF00130.22 ORY44183.1 - 0.081 12.8 3.7 0.15 12.0 3.7 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Glycogen_syn PF05693.13 ORY44184.1 - 1.3e-282 939.2 5.7 7e-171 570.0 3.7 3.5 2 1 0 2 2 2 2 Glycogen synthase Glyco_transf_5 PF08323.11 ORY44184.1 - 1.1e-06 28.5 0.8 2.8e-06 27.2 0.8 1.7 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 ORY44184.1 - 0.00024 21.2 0.8 0.00049 20.1 0.8 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 ORY44184.1 - 0.0014 18.2 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ORY44184.1 - 0.0027 18.2 1.6 0.0064 16.9 1.6 1.7 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 ORY44184.1 - 0.0067 16.9 0.0 0.016 15.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 IQ PF00612.27 ORY44185.1 - 0.037 13.8 0.1 0.22 11.4 0.1 2.2 2 0 0 2 2 2 0 IQ calmodulin-binding motif cIII PF08134.11 ORY44186.1 - 0.078 12.7 0.7 0.23 11.2 0.7 1.8 1 0 0 1 1 1 0 cIII protein family Macscav_rec PF03523.13 ORY44188.1 - 0.15 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Macrophage scavenger receptor RRP36 PF06102.12 ORY44191.1 - 1e-39 136.2 28.1 1.2e-39 135.9 28.1 1.1 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 Neur_chan_memb PF02932.16 ORY44191.1 - 1.3 9.1 5.4 1.4 8.9 5.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pannexin_like PF12534.8 ORY44191.1 - 6 5.9 7.7 8 5.4 7.7 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 cNMP_binding PF00027.29 ORY44192.1 - 4e-17 62.1 0.0 8.1e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 ORY44192.1 - 1.4 8.1 9.6 6.9 5.8 9.6 1.9 1 1 0 1 1 1 0 Ion transport protein Vezatin PF12632.7 ORY44193.1 - 0.082 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes Galactosyl_T PF01762.21 ORY44194.1 - 2.9e-05 24.0 0.0 4e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase ABC_tran PF00005.27 ORY44195.1 - 5.2e-46 156.6 0.2 7.5e-27 94.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORY44195.1 - 1.2e-32 113.7 33.9 1.1e-30 107.2 14.7 3.6 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 ORY44195.1 - 1.4e-07 31.2 0.3 0.002 17.6 0.0 3.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ORY44195.1 - 1.2e-05 25.3 4.2 2.1 8.1 1.0 4.3 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ORY44195.1 - 1.6e-05 25.5 0.4 0.0025 18.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ORY44195.1 - 5.5e-05 22.8 1.1 0.16 11.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY44195.1 - 0.0038 17.3 1.4 0.94 9.6 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY44195.1 - 0.0099 16.3 1.8 1.1 9.6 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 ORY44195.1 - 0.013 16.0 2.4 6.1 7.3 0.1 3.7 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 ORY44195.1 - 0.034 14.1 1.9 1 9.2 0.3 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_25 PF13481.6 ORY44195.1 - 0.04 13.5 0.3 2 8.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ORY44195.1 - 0.07 13.4 1.4 12 6.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 ORY44195.1 - 0.37 10.5 1.7 27 4.4 0.1 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF87 PF01935.17 ORY44195.1 - 0.57 10.2 2.8 5 7.1 0.3 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain T2SSE PF00437.20 ORY44195.1 - 0.8 8.7 4.5 1.8 7.6 0.2 2.7 3 0 0 3 3 3 0 Type II/IV secretion system protein dbPDZ_assoc PF16610.5 ORY44195.1 - 3.9 7.8 5.7 8.4 6.7 5.7 1.5 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 PRIMA1 PF16101.5 ORY44196.1 - 0.026 14.5 0.1 0.026 14.5 0.1 2.3 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 DUF1772 PF08592.11 ORY44196.1 - 0.25 11.7 6.3 0.44 10.8 0.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF2970 PF11174.8 ORY44196.1 - 0.34 10.8 0.0 0.34 10.8 0.0 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2970) DC_STAMP PF07782.13 ORY44196.1 - 3.7 7.3 6.3 0.45 10.3 1.3 2.1 1 1 1 2 2 2 0 DC-STAMP-like protein MnhB PF04039.13 ORY44196.1 - 4 7.8 12.7 5.1 7.4 2.9 3.2 2 1 1 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter TPMT PF05724.11 ORY44197.1 - 0.088 12.5 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) FWWh PF14922.6 ORY44197.1 - 0.12 12.3 3.6 0.82 9.6 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function Rod_C PF10493.9 ORY44198.1 - 4e-52 177.3 0.8 7.7e-51 173.1 0.8 2.4 1 1 0 1 1 1 1 Rough deal protein C-terminal region TPR_14 PF13428.6 ORY44198.1 - 0.089 13.7 0.2 61 4.8 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat RhoGEF PF00621.20 ORY44200.1 - 7.3e-06 26.3 3.8 1.5e-05 25.3 3.8 1.5 1 0 0 1 1 1 1 RhoGEF domain Peptidase_C2 PF00648.21 ORY44201.1 - 4.7e-69 232.7 0.0 8.2e-69 231.9 0.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 ORY44201.1 - 1.4e-21 77.2 0.0 3.5e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Calpain large subunit, domain III C2 PF00168.30 ORY44201.1 - 3e-10 40.3 0.0 7.1e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 C2 domain Ubiquitin_2 PF14560.6 ORY44202.1 - 2.2e-25 88.9 0.0 7e-25 87.3 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-like domain CAP_GLY PF01302.25 ORY44202.1 - 1.9e-22 79.1 1.3 3.8e-22 78.1 1.1 1.7 2 0 0 2 2 2 1 CAP-Gly domain ubiquitin PF00240.23 ORY44202.1 - 0.005 16.6 0.0 0.018 14.8 0.0 2.0 2 1 0 2 2 2 1 Ubiquitin family FCH PF00611.23 ORY44203.1 - 3.7e-15 56.0 0.2 3.7e-15 56.0 0.2 2.1 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 ORY44203.1 - 4.3e-08 32.6 0.1 9.3e-08 31.6 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY44203.1 - 2.8e-05 23.9 0.0 5.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF724 PF05266.14 ORY44203.1 - 0.027 14.3 8.5 0.76 9.6 6.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Z1 PF10593.9 ORY44203.1 - 0.21 11.0 4.9 0.6 9.6 4.7 1.9 1 1 0 1 1 1 0 Z1 domain FapA PF03961.13 ORY44203.1 - 0.22 10.1 6.7 7.9 5.0 6.1 2.4 2 1 0 2 2 2 0 Flagellar Assembly Protein A DUF2347 PF09804.9 ORY44203.1 - 0.23 11.0 1.9 0.46 10.0 1.9 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) MitMem_reg PF13012.6 ORY44203.1 - 0.28 11.6 2.1 1.3 9.5 0.3 2.7 3 0 0 3 3 3 0 Maintenance of mitochondrial structure and function YicC_N PF03755.13 ORY44203.1 - 0.9 10.0 6.1 5.9 7.3 0.1 2.6 1 1 1 2 2 2 0 YicC-like family, N-terminal region DUF3450 PF11932.8 ORY44203.1 - 0.91 8.8 14.6 0.58 9.4 5.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 ORY44203.1 - 4.2 7.9 18.5 7.2 7.1 0.6 3.6 3 1 0 3 3 3 0 Apg6 coiled-coil region DUF4140 PF13600.6 ORY44203.1 - 6.6 7.2 7.2 33 5.0 0.1 3.6 3 2 0 3 3 2 0 N-terminal domain of unknown function (DUF4140) GAS PF13851.6 ORY44203.1 - 9.4 5.5 17.5 11 5.3 10.0 2.6 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DASH_Dad2 PF08654.10 ORY44204.1 - 0.0047 17.3 2.0 0.038 14.4 0.7 2.8 1 1 1 2 2 2 1 DASH complex subunit Dad2 Phage_GPO PF05929.11 ORY44204.1 - 0.12 12.0 9.1 0.21 11.2 0.6 2.4 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase TSC22 PF01166.18 ORY44204.1 - 0.28 11.5 10.5 2.3 8.6 0.2 4.0 3 1 1 4 4 4 0 TSC-22/dip/bun family DUF724 PF05266.14 ORY44204.1 - 0.34 10.7 20.1 0.59 9.9 2.5 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF724) DUF4795 PF16043.5 ORY44204.1 - 0.65 9.6 15.9 2.1 7.9 14.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Spc7 PF08317.11 ORY44204.1 - 0.69 8.7 24.1 1 8.2 1.5 3.5 1 1 2 3 3 3 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 ORY44204.1 - 0.76 9.8 28.0 1 9.4 8.9 3.4 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.9 ORY44204.1 - 1.2 9.4 24.1 0.94 9.7 8.8 2.7 2 1 0 2 2 2 0 JNK_SAPK-associated protein-1 JIP_LZII PF16471.5 ORY44204.1 - 1.9 8.7 13.2 1.6 9.0 0.7 4.0 3 1 1 4 4 4 0 JNK-interacting protein leucine zipper II Snapin_Pallidin PF14712.6 ORY44204.1 - 4.8 7.7 18.4 1.6 9.2 1.9 4.0 2 1 1 3 3 3 0 Snapin/Pallidin Hid1 PF12722.7 ORY44205.1 - 8.4e-138 460.8 40.9 3.6e-74 250.4 3.0 5.0 1 1 3 4 4 4 3 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 ORY44205.1 - 5.9e-101 338.8 0.0 1.6e-100 337.4 0.0 1.6 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein AF-4 PF05110.13 ORY44205.1 - 0.083 11.0 22.7 0.13 10.3 22.7 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Presenilin PF01080.17 ORY44205.1 - 0.26 10.0 13.2 0.46 9.2 13.2 1.4 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 ORY44205.1 - 1.3 7.7 14.8 2.2 7.0 14.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Neur_chan_memb PF02932.16 ORY44205.1 - 4.9 7.1 13.1 8.9 6.3 13.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1230 PF06799.11 ORY44206.1 - 0.0089 16.1 2.0 0.027 14.6 0.1 2.4 2 1 0 2 2 2 1 Conserved in the green lineage and diatoms 27 COX4_pro_2 PF07835.12 ORY44206.1 - 0.23 11.6 8.1 5.9 7.1 0.0 4.0 4 0 0 4 4 4 0 Bacterial aa3 type cytochrome c oxidase subunit IV TMEM132D_C PF15706.5 ORY44207.1 - 0.085 12.6 0.0 0.085 12.6 0.0 1.7 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term LRR_8 PF13855.6 ORY44208.1 - 1.2e-06 28.1 1.1 1.2e-06 28.1 1.1 2.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY44208.1 - 2.8e-05 24.4 3.6 4.6e-05 23.7 0.7 2.4 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY44208.1 - 8.1e-05 22.7 5.6 0.0069 16.8 0.3 3.3 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_6 PF13516.6 ORY44208.1 - 0.11 12.6 2.1 0.84 9.8 0.2 2.4 2 0 0 2 2 2 0 Leucine Rich repeat Peptidase_M41 PF01434.18 ORY44209.1 - 3.3e-68 229.3 0.1 5.1e-68 228.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 ORY44209.1 - 2.4e-42 144.5 0.0 5.7e-42 143.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY44209.1 - 7.6e-12 44.8 0.1 2e-11 43.5 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 ORY44209.1 - 1.6e-08 34.9 0.0 4.3e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular RuvB_N PF05496.12 ORY44209.1 - 0.0013 18.5 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY44209.1 - 0.0028 18.1 0.7 0.017 15.5 0.2 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY44209.1 - 0.01 16.1 0.2 0.62 10.3 0.2 2.7 1 1 1 2 2 2 0 AAA domain IstB_IS21 PF01695.17 ORY44209.1 - 0.015 15.0 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein CDC45 PF02724.14 ORY44209.1 - 0.022 13.1 4.3 0.032 12.5 4.3 1.1 1 0 0 1 1 1 0 CDC45-like protein TIP49 PF06068.13 ORY44209.1 - 0.031 13.5 0.1 0.062 12.5 0.1 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain RR_TM4-6 PF06459.12 ORY44209.1 - 0.034 14.0 6.1 0.062 13.1 6.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_5 PF07728.14 ORY44209.1 - 0.047 13.7 0.2 0.26 11.3 0.2 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF913 PF06025.12 ORY44209.1 - 0.053 12.5 1.7 0.085 11.8 1.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) AAA_18 PF13238.6 ORY44209.1 - 0.12 12.9 0.0 3.8 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 ORY44209.1 - 0.15 12.2 0.0 0.15 12.2 0.0 2.2 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) CDC27 PF09507.10 ORY44209.1 - 0.19 11.1 20.0 0.29 10.5 20.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Tim54 PF11711.8 ORY44209.1 - 0.2 10.4 8.6 0.37 9.5 8.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Coilin_N PF15862.5 ORY44209.1 - 0.25 11.1 11.6 0.49 10.2 11.6 1.5 1 0 0 1 1 1 0 Coilin N-terminus NARP1 PF12569.8 ORY44209.1 - 0.5 9.2 10.3 0.78 8.6 10.3 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 NOA36 PF06524.12 ORY44209.1 - 0.59 9.4 5.9 0.91 8.8 5.9 1.2 1 0 0 1 1 1 0 NOA36 protein AAA_11 PF13086.6 ORY44209.1 - 0.74 9.5 5.1 8.1 6.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain PBP1_TM PF14812.6 ORY44209.1 - 0.86 10.0 12.0 1.7 9.1 12.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sec62 PF03839.16 ORY44209.1 - 1 8.8 4.3 1.8 8.0 4.3 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 TLP-20 PF06088.11 ORY44209.1 - 1 9.2 8.7 2 8.3 8.7 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DNA_pol_phi PF04931.13 ORY44209.1 - 1.6 6.8 11.3 2.7 6.0 11.3 1.3 1 0 0 1 1 1 0 DNA polymerase phi RNA_pol_Rpc4 PF05132.14 ORY44209.1 - 1.6 9.2 9.6 3 8.3 9.6 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 GEN1_C PF18380.1 ORY44209.1 - 2 9.3 8.2 5.6 7.9 8.2 1.8 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain PcfK PF14058.6 ORY44209.1 - 3.4 8.0 16.7 8.5 6.7 16.7 1.7 1 0 0 1 1 1 0 PcfK-like protein Presenilin PF01080.17 ORY44209.1 - 5.6 5.6 5.8 8.4 5.0 5.8 1.2 1 0 0 1 1 1 0 Presenilin SpoIIP PF07454.11 ORY44209.1 - 9.6 5.6 10.1 16 4.8 10.1 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Pkinase PF00069.25 ORY44210.1 - 5.1e-39 134.2 0.0 1.7e-38 132.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY44210.1 - 1.9e-22 79.8 0.0 3e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY44210.1 - 1.1e-05 25.0 0.0 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY44210.1 - 0.011 15.1 0.0 0.1 12.0 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY44210.1 - 0.013 14.3 0.0 0.032 13.0 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase Asp PF00026.23 ORY44212.1 - 6.6e-29 101.3 0.1 8.4e-29 101.0 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 ORY44212.1 - 2.9e-09 36.9 0.5 1.1e-06 28.5 0.0 2.1 2 0 0 2 2 2 2 Xylanase inhibitor C-terminal adh_short PF00106.25 ORY44215.1 - 2.1e-25 89.3 0.2 3.6e-21 75.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY44215.1 - 2.2e-14 53.6 0.0 9.4e-13 48.3 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY44215.1 - 3.6e-05 23.7 0.0 6.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 ORY44215.1 - 0.16 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Fungal_trans PF04082.18 ORY44216.1 - 0.0041 16.2 0.0 0.012 14.6 0.0 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain PBP_sp32 PF07222.12 ORY44216.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Asp PF00026.23 ORY44218.1 - 1.5e-37 129.7 0.0 2.1e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 ORY44218.1 - 3.8e-10 39.8 0.0 2.9e-09 36.9 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.23 ORY44220.1 - 2.8e-105 352.2 0.0 3.4e-105 351.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY44220.1 - 3e-15 56.9 0.2 1.3e-08 35.3 0.2 3.2 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORY44220.1 - 0.00023 21.8 0.1 0.46 11.2 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 ORY44220.1 - 0.0024 18.4 0.0 3 8.5 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 ORY44220.1 - 0.0056 16.5 0.0 0.029 14.1 0.0 2.2 3 0 0 3 3 3 1 Xylanase inhibitor C-terminal RTA1 PF04479.13 ORY44221.1 - 2.7e-52 177.4 9.5 3.7e-52 177.0 9.5 1.2 1 0 0 1 1 1 1 RTA1 like protein Phage_holin_5_2 PF16079.5 ORY44221.1 - 0.87 10.0 7.6 0.56 10.6 2.9 2.5 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V RTA1 PF04479.13 ORY44222.1 - 3.6e-27 95.3 1.8 5.4e-18 65.4 0.1 3.0 2 1 1 3 3 3 3 RTA1 like protein Nodulin-like PF06813.13 ORY44222.1 - 0.049 13.1 0.2 0.18 11.2 0.0 1.9 2 0 0 2 2 2 0 Nodulin-like MLVIN_C PF18697.1 ORY44222.1 - 0.15 12.2 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain RTA1 PF04479.13 ORY44223.1 - 8.7e-53 179.0 10.3 1.1e-52 178.7 10.3 1.1 1 0 0 1 1 1 1 RTA1 like protein Nodulin-like PF06813.13 ORY44223.1 - 0.14 11.6 6.6 1.2 8.5 6.2 2.6 1 1 0 1 1 1 0 Nodulin-like YtpI PF14007.6 ORY44223.1 - 0.31 11.2 0.1 0.31 11.2 0.1 3.7 5 1 1 6 6 6 0 YtpI-like protein MscL PF01741.18 ORY44224.1 - 1.3e-25 90.0 0.0 2.1e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL UPF0547 PF10571.9 ORY44224.1 - 7.8 6.7 9.6 15 5.8 9.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 MscL PF01741.18 ORY44225.1 - 7.6e-34 116.6 2.3 9.5e-34 116.3 2.3 1.1 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL DUF1206 PF06724.11 ORY44225.1 - 4.4 7.5 7.8 0.12 12.5 1.1 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) NFACT-C PF11923.8 ORY44227.1 - 4.3e-26 90.9 1.6 1.2e-25 89.5 0.2 2.6 2 0 0 2 2 2 1 NFACT protein C-terminal domain FbpA PF05833.11 ORY44227.1 - 4.6e-26 91.6 11.6 1.6e-17 63.4 0.0 2.5 3 0 0 3 3 3 2 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 ORY44227.1 - 2.8e-19 69.7 0.0 9e-19 68.1 0.0 1.8 1 0 0 1 1 1 1 NFACT protein RNA binding domain TPR_12 PF13424.6 ORY44228.1 - 7.7e-126 410.6 67.6 2e-16 60.1 0.8 9.8 2 2 9 13 13 13 13 Tetratricopeptide repeat TPR_10 PF13374.6 ORY44228.1 - 3.2e-112 363.8 2.6 8.9e-08 31.8 0.0 15.2 16 0 0 16 16 15 13 Tetratricopeptide repeat TPR_2 PF07719.17 ORY44228.1 - 2.2e-75 242.8 57.9 3.8e-05 23.5 0.5 15.6 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_8 PF13181.6 ORY44228.1 - 5.7e-64 207.1 78.2 7.4e-05 22.7 0.5 15.7 16 0 0 16 16 15 13 Tetratricopeptide repeat TPR_7 PF13176.6 ORY44228.1 - 3.8e-56 183.1 30.3 0.00044 20.1 0.1 14.0 14 0 0 14 14 13 12 Tetratricopeptide repeat TPR_1 PF00515.28 ORY44228.1 - 3e-51 169.3 75.3 0.00035 20.2 0.9 15.3 15 0 0 15 15 15 13 Tetratricopeptide repeat TPR_14 PF13428.6 ORY44228.1 - 1.1e-41 137.9 1.1 0.38 11.7 0.0 14.4 13 1 1 14 14 14 9 Tetratricopeptide repeat TPR_17 PF13431.6 ORY44228.1 - 6.1e-27 92.0 5.5 1.6 9.3 0.0 15.1 15 1 0 15 15 12 5 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY44228.1 - 1.6e-21 77.1 21.5 1.6e-07 31.1 2.0 5.5 2 1 3 5 5 5 4 MalT-like TPR region TPR_16 PF13432.6 ORY44228.1 - 3e-21 75.8 21.0 1.1 10.0 0.4 13.1 12 1 0 12 12 12 6 Tetratricopeptide repeat TPR_6 PF13174.6 ORY44228.1 - 1.5e-20 72.3 47.6 0.5 11.1 0.1 14.1 14 0 0 14 14 13 6 Tetratricopeptide repeat TPR_19 PF14559.6 ORY44228.1 - 7e-20 71.3 30.9 0.00026 21.4 0.5 9.5 4 3 8 12 12 11 10 Tetratricopeptide repeat TPR_4 PF07721.14 ORY44228.1 - 1.7e-14 52.9 0.0 38 5.3 0.0 11.5 12 0 0 12 12 12 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY44228.1 - 6.2e-12 45.4 43.7 4.9 7.3 0.1 14.0 15 0 0 15 15 13 2 Fis1 C-terminal tetratricopeptide repeat TIR_2 PF13676.6 ORY44228.1 - 8.7e-10 39.2 0.1 1.3e-08 35.4 0.0 2.6 2 0 0 2 2 2 1 TIR domain PPR PF01535.20 ORY44228.1 - 1.7e-09 37.2 5.3 1e+02 3.5 0.0 11.8 12 0 0 12 12 12 0 PPR repeat Toxin_13 PF07822.11 ORY44228.1 - 7.5e-08 32.4 1.6 33 4.7 0.0 9.9 10 1 1 11 11 11 0 Neurotoxin B-IV-like protein HTH_Tnp_Mu_2 PF09039.11 ORY44228.1 - 2.7e-07 30.6 3.7 12 6.0 0.0 7.4 5 2 3 9 9 8 0 Mu DNA binding, I gamma subdomain MIT PF04212.18 ORY44228.1 - 2e-06 27.8 65.8 3.9 7.6 0.3 13.4 6 3 7 13 13 13 1 MIT (microtubule interacting and transport) domain NB-ARC PF00931.22 ORY44228.1 - 2.6e-06 26.8 0.0 5.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain ANAPC3 PF12895.7 ORY44228.1 - 2.8e-06 27.4 35.8 4 7.7 2.3 11.8 3 2 9 12 12 12 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 ORY44228.1 - 0.0003 20.9 0.0 33 4.7 0.0 6.2 4 2 3 8 8 8 0 Tetratricopeptide repeat AAA_22 PF13401.6 ORY44228.1 - 0.00067 19.9 0.0 0.0025 18.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 ORY44228.1 - 0.00076 19.4 0.0 0.0035 17.3 0.0 2.1 2 0 0 2 2 2 1 NACHT domain Glyoxalase PF00903.25 ORY44228.1 - 0.0022 18.2 0.1 1.6e+02 2.5 0.0 7.7 8 3 2 10 10 9 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF4945 PF16303.5 ORY44228.1 - 0.0042 17.0 14.0 5.7 6.9 0.0 7.3 6 3 2 8 8 8 1 Domain of unknown function (DUF4945) AAA_16 PF13191.6 ORY44228.1 - 0.018 15.5 0.0 0.057 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain FYRN PF05964.14 ORY44228.1 - 0.037 13.9 0.0 1.1e+02 2.8 0.0 5.8 8 0 0 8 8 8 0 F/Y-rich N-terminus Ribosomal_S19 PF00203.21 ORY44228.1 - 0.055 13.4 0.2 3.5 7.6 0.0 4.1 4 0 0 4 4 4 0 Ribosomal protein S19 DUF1657 PF07870.11 ORY44228.1 - 8.4 6.4 42.3 49 3.9 0.1 13.2 14 0 0 14 14 14 0 Protein of unknown function (DUF1657) BPS1 PF05633.11 ORY44284.1 - 0.49 9.4 1.9 0.71 8.8 1.9 1.1 1 0 0 1 1 1 0 Protein BYPASS1-related SGP PF17228.2 ORY44286.1 - 0.00049 20.9 11.5 0.0011 19.8 11.5 1.5 1 0 0 1 1 1 1 Sulphur globule protein DUF1921 PF09081.10 ORY44287.1 - 0.23 11.7 2.3 21 5.5 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1921) Methyltransf_31 PF13847.6 ORY44288.1 - 0.087 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Macoilin PF09726.9 ORY44289.1 - 8.7 4.8 10.0 11 4.4 10.0 1.1 1 0 0 1 1 1 0 Macoilin family Acetyltransf_1 PF00583.25 ORY44290.1 - 1.3e-14 54.5 0.0 1.6e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY44290.1 - 1.7e-10 41.2 0.0 2.6e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY44290.1 - 4.8e-06 26.5 0.0 7.5e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORY44290.1 - 0.00012 22.7 0.0 0.00015 22.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY44290.1 - 0.003 17.5 0.0 0.0062 16.5 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 ORY44290.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Nipped-B_C PF12830.7 ORY44291.1 - 2.5e-24 86.3 0.2 1e-19 71.2 0.4 3.5 3 0 0 3 3 3 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 ORY44291.1 - 1.1e-08 35.2 4.2 4.3e-08 33.3 4.2 2.2 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 ORY44291.1 - 0.0023 18.0 0.1 4.8 7.7 0.0 4.1 3 0 0 3 3 3 2 HEAT repeat Ldi PF18566.1 ORY44291.1 - 0.025 14.1 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 Linalool dehydratase/isomerase DUF2207 PF09972.9 ORY44292.1 - 0.018 13.8 0.9 0.018 13.8 0.9 1.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) SPC25 PF06703.11 ORY44292.1 - 0.036 13.9 3.2 0.098 12.4 1.0 2.3 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) zinc_ribbon_10 PF10058.9 ORY44292.1 - 0.25 11.1 6.1 0.48 10.2 1.4 2.5 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF2721 PF11026.8 ORY44292.1 - 7.8 6.4 9.7 1.1 9.1 4.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) RPE65 PF03055.15 ORY44294.1 - 5.3e-74 250.1 0.0 6.6e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein MpPF26 PF07666.11 ORY44295.1 - 0.001 19.2 0.4 0.0021 18.2 0.4 1.5 1 0 0 1 1 1 1 M penetrans paralogue family 26 UPF0114 PF03350.16 ORY44295.1 - 0.043 14.0 3.3 0.084 13.1 3.3 1.5 1 0 0 1 1 1 0 Uncharacterized protein family, UPF0114 UPF0139 PF03669.13 ORY44296.1 - 2e-18 66.0 0.0 2.4e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Gram_pos_anchor PF00746.21 ORY44296.1 - 0.18 11.7 4.7 1 9.4 0.3 2.2 2 0 0 2 2 2 0 LPXTG cell wall anchor motif Pro_CA PF00484.19 ORY44297.1 - 6.5e-22 78.5 0.2 7.3e-21 75.1 0.2 1.9 1 1 0 1 1 1 1 Carbonic anhydrase DUF948 PF06103.11 ORY44302.1 - 0.013 15.7 0.7 0.71 10.2 0.2 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 ORY44302.1 - 0.017 15.2 0.8 0.066 13.2 0.4 2.2 1 1 1 2 2 2 0 Laminin Domain II HIP1_clath_bdg PF16515.5 ORY44302.1 - 0.055 14.1 0.4 0.7 10.5 0.1 2.6 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Seryl_tRNA_N PF02403.22 ORY44302.1 - 0.096 12.9 0.9 0.3 11.3 0.9 1.9 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Allexi_40kDa PF05549.11 ORY44302.1 - 0.14 11.7 1.5 1.2 8.6 0.1 2.4 1 1 0 2 2 2 0 Allexivirus 40kDa protein TFIID-18kDa PF02269.16 ORY44304.1 - 6e-19 67.9 0.1 9.8e-19 67.2 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Ecl1 PF12855.7 ORY44305.1 - 1e-08 36.5 5.7 1.3e-08 36.3 5.7 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins PLATZ PF04640.14 ORY44305.1 - 0.031 14.9 1.3 0.06 14.0 1.3 1.5 1 0 0 1 1 1 0 PLATZ transcription factor VATC PF18716.1 ORY44305.1 - 0.23 11.3 3.9 0.98 9.3 3.9 1.9 1 1 0 1 1 1 0 Vms1-associating treble clef domain zf-FLZ PF04570.14 ORY44305.1 - 0.36 10.3 2.6 1.9 8.1 2.6 2.0 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 DUF515 PF04415.12 ORY44306.1 - 0.27 9.6 4.5 0.38 9.1 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) IF4E PF01652.18 ORY44307.1 - 4.6e-45 153.3 0.0 5.8e-45 152.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E PA26 PF04636.13 ORY44308.1 - 1.1 8.0 4.6 2.3 7.1 4.6 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CENP-B_dimeris PF09026.10 ORY44308.1 - 1.4 9.4 9.4 16 6.0 6.9 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NPR3 PF03666.13 ORY44308.1 - 2.3 6.9 9.6 5.7 5.6 9.6 1.6 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Connexin PF00029.19 ORY44308.1 - 6.1 6.5 7.6 12 5.5 7.6 1.5 1 0 0 1 1 1 0 Connexin SAPS PF04499.15 ORY44308.1 - 8 5.1 13.4 0.4 9.4 6.6 1.9 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Acyltransferase PF01553.21 ORY44310.1 - 5.9e-32 110.1 0.0 7.6e-32 109.8 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Peptidase_M28 PF04389.17 ORY44311.1 - 6.9e-20 71.6 0.0 1.1e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 SLATT_1 PF18181.1 ORY44312.1 - 0.35 10.8 1.7 0.49 10.3 0.2 2.0 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 YbgT_YccB PF08173.11 ORY44312.1 - 2.5 8.3 9.9 0.55 10.4 2.5 3.1 2 1 1 3 3 3 0 Membrane bound YbgT-like protein Peptidase_M28 PF04389.17 ORY44313.1 - 1.3e-31 109.9 0.0 2.2e-31 109.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 ORY44313.1 - 0.034 13.6 0.8 0.079 12.4 0.1 2.0 2 0 0 2 2 2 0 Nicastrin Glyco_transf_90 PF05686.12 ORY44314.1 - 7.6e-26 90.9 0.0 1.7e-22 79.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 90 JmjC PF02373.22 ORY44315.1 - 3.5e-41 140.2 0.1 6e-41 139.5 0.1 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.16 ORY44315.1 - 8.1e-08 32.5 8.3 1.8e-07 31.4 8.3 1.7 1 0 0 1 1 1 1 C5HC2 zinc finger PLU-1 PF08429.11 ORY44315.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 PLU-1-like protein Zn-ribbon_8 PF09723.10 ORY44318.1 - 1.6 8.9 5.4 7.3 6.8 0.6 3.2 3 0 0 3 3 3 0 Zinc ribbon domain Resolvase PF00239.21 ORY44319.1 - 1.5e-15 57.6 0.4 3.6e-15 56.3 0.4 1.7 1 1 0 1 1 1 1 Resolvase, N terminal domain Peptidase_A25 PF03418.14 ORY44319.1 - 0.064 12.1 0.0 0.094 11.6 0.0 1.2 1 0 0 1 1 1 0 Germination protease Peptidase_M28 PF04389.17 ORY44320.1 - 6.3e-30 104.3 0.0 8e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.14 ORY44320.1 - 0.0031 16.6 0.0 0.0062 15.6 0.0 1.4 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase Peptidase_M20 PF01546.28 ORY44320.1 - 0.021 14.5 0.0 0.029 14.1 0.0 1.4 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 PUF PF00806.19 ORY44321.1 - 1.3e-17 62.4 0.2 0.0019 17.8 0.0 6.9 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat Ank_4 PF13637.6 ORY44322.1 - 1.3e-07 32.0 0.0 0.055 14.1 0.0 3.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY44322.1 - 0.0094 16.5 0.0 0.33 11.6 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) F-box-like PF12937.7 ORY44322.1 - 0.075 12.9 0.6 0.14 12.1 0.6 1.4 1 0 0 1 1 1 0 F-box-like TetR_C_8 PF14278.6 ORY44322.1 - 0.076 13.1 0.6 0.58 10.3 0.1 2.6 2 1 1 3 3 3 0 Transcriptional regulator C-terminal region Cas9_Topo PF17894.1 ORY44322.1 - 0.14 12.3 0.0 2.3 8.4 0.0 2.6 2 1 0 2 2 2 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 LRR_8 PF13855.6 ORY44324.1 - 1.5e-06 27.8 11.9 0.00053 19.7 1.7 2.6 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY44324.1 - 1.3e-05 25.4 10.6 0.0038 17.6 0.9 3.4 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY44324.1 - 0.00059 20.0 12.4 4.7 8.2 0.1 4.7 4 1 1 5 5 5 2 Leucine Rich Repeat LRR_2 PF07723.13 ORY44324.1 - 0.046 14.4 0.0 11 6.9 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich Repeat LSPR PF06049.12 ORY44324.1 - 1.3 9.2 3.4 30 5.0 0.1 2.8 2 0 0 2 2 2 0 Coagulation Factor V LSPD Repeat Sel1 PF08238.12 ORY44325.1 - 3.8e-16 59.2 6.3 5.4e-08 33.3 1.5 2.6 2 0 0 2 2 2 2 Sel1 repeat TIR_2 PF13676.6 ORY44325.1 - 3.4e-14 53.5 0.0 8.8e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 TIR domain NACHT PF05729.12 ORY44325.1 - 4.9e-09 36.3 0.0 1e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain SAM_2 PF07647.17 ORY44325.1 - 5.7e-05 23.1 0.0 0.0012 18.9 0.0 2.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORY44325.1 - 0.0031 17.9 0.1 0.0066 16.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TIR PF01582.20 ORY44325.1 - 0.0082 16.0 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 TIR domain XisI PF08869.11 ORY44325.1 - 0.012 16.0 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 XisI protein AAA_16 PF13191.6 ORY44325.1 - 0.028 14.8 0.0 0.07 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain LRR_8 PF13855.6 ORY44326.1 - 9.7e-11 41.3 9.8 6.3e-06 25.9 0.7 3.4 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY44326.1 - 2.4e-10 40.5 12.7 0.0014 18.9 0.1 5.3 2 1 6 8 8 8 5 Leucine Rich repeats (2 copies) F-box PF00646.33 ORY44326.1 - 0.00016 21.4 1.2 0.00051 19.8 1.2 1.9 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.33 ORY44326.1 - 0.00021 21.4 5.7 14 6.7 0.1 6.2 5 1 0 5 5 5 1 Leucine Rich Repeat F-box-like PF12937.7 ORY44326.1 - 0.0017 18.2 1.3 0.0063 16.4 1.3 2.0 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 ORY44326.1 - 4.1 7.7 16.1 3.9 7.8 0.2 5.8 7 0 0 7 7 7 0 Leucine Rich repeat HAT_KAT11 PF08214.11 ORY44328.1 - 4.5e-05 22.9 0.0 5.9e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Pkinase PF00069.25 ORY44329.1 - 2.2e-34 119.0 0.0 3.2e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY44329.1 - 6.9e-16 58.3 0.0 9.9e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY44329.1 - 0.036 13.4 0.0 0.073 12.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 ORY44330.1 - 4.3e-37 127.9 0.0 9.5e-37 126.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY44330.1 - 2.8e-21 76.0 0.0 4.6e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2009 PF09418.10 ORY44330.1 - 0.028 13.5 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Pkinase_fungal PF17667.1 ORY44330.1 - 0.038 12.8 0.9 0.06 12.1 0.8 1.5 1 1 0 1 1 1 0 Fungal protein kinase MBR1 PF17058.5 ORY44330.1 - 0.11 12.8 2.3 0.21 11.9 2.3 1.4 1 0 0 1 1 1 0 Mitochondrial biogenesis regulation protein 1 SAM_1 PF00536.30 ORY44331.1 - 0.0073 16.7 0.0 0.018 15.4 0.0 1.7 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) Amnionless PF14828.6 ORY44331.1 - 0.0085 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Amnionless SAM_PNT PF02198.16 ORY44331.1 - 0.04 13.9 0.0 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF347 PF03988.12 ORY44331.1 - 0.13 12.5 0.7 0.34 11.1 0.3 2.0 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Syndecan PF01034.20 ORY44331.1 - 0.18 11.8 0.4 0.37 10.7 0.4 1.4 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.15 ORY44331.1 - 4.2 7.2 8.4 0.42 10.4 3.6 1.7 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 NAPRTase_C PF17956.1 ORY44332.1 - 0.0074 16.7 1.8 0.011 16.1 0.9 1.9 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain GST_N_4 PF17172.4 ORY44332.1 - 0.12 13.1 0.5 0.12 13.1 0.5 2.2 2 2 1 3 3 3 0 Glutathione S-transferase N-terminal domain Bap31_Bap29_C PF18035.1 ORY44332.1 - 0.17 11.9 11.8 0.3 11.1 1.2 4.2 4 1 0 4 4 4 0 Bap31/Bap29 cytoplasmic coiled-coil domain Scaffolding_pro PF11418.8 ORY44332.1 - 7.3 7.2 11.7 0.8 10.3 2.6 3.3 1 1 3 4 4 4 0 Phi29 scaffolding protein FAM184 PF15665.5 ORY44332.1 - 8 6.2 30.0 0.035 13.9 12.4 2.3 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B ADK PF00406.22 ORY44333.1 - 0.0021 18.1 0.0 0.0028 17.8 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase vATP-synt_AC39 PF01992.16 ORY44334.1 - 3e-99 332.7 5.0 7.7e-99 331.4 5.0 1.7 1 1 0 1 1 1 1 ATP synthase (C/AC39) subunit PDE4_UCR PF18100.1 ORY44336.1 - 0.18 12.5 1.0 0.81 10.3 0.2 2.0 2 0 0 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) DUF2157 PF09925.9 ORY44338.1 - 6.7 6.5 10.0 11 5.8 8.5 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) AA_permease_2 PF13520.6 ORY44339.1 - 2.3e-24 86.0 25.5 3.3e-24 85.5 25.5 1.2 1 0 0 1 1 1 1 Amino acid permease Adeno_E3_CR2 PF02439.15 ORY44341.1 - 0.02 14.7 0.7 0.033 13.9 0.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SLAC1 PF03595.17 ORY44341.1 - 0.054 12.7 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Voltage-dependent anion channel COX2_TM PF02790.15 ORY44341.1 - 0.071 13.3 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain Hum_adeno_E3A PF05393.11 ORY44341.1 - 0.1 12.6 0.1 0.15 12.0 0.1 1.2 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Syndecan PF01034.20 ORY44341.1 - 0.16 11.9 0.9 0.27 11.2 0.9 1.3 1 0 0 1 1 1 0 Syndecan domain SIT PF15330.6 ORY44341.1 - 0.16 12.4 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Microcin PF03526.13 ORY44341.1 - 0.18 11.6 0.2 0.32 10.8 0.2 1.3 1 0 0 1 1 1 0 Colicin E1 (microcin) immunity protein RCR PF12273.8 ORY44342.1 - 0.067 13.9 11.7 0.15 12.7 11.7 1.6 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red G_path_suppress PF15991.5 ORY44342.1 - 7.4 6.6 10.9 9.7 6.2 10.9 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor DUF1180 PF06679.12 ORY44343.1 - 0.19 12.1 0.2 0.23 11.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF2919 PF11143.8 ORY44344.1 - 0.00081 19.7 0.9 0.002 18.4 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2919) RCR PF12273.8 ORY44344.1 - 0.012 16.3 3.8 0.02 15.6 3.8 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF4448 PF14610.6 ORY44344.1 - 0.042 13.6 0.6 0.08 12.7 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Mid2 PF04478.12 ORY44344.1 - 0.2 11.5 1.1 0.38 10.6 1.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Shisa PF13908.6 ORY44344.1 - 0.28 11.4 2.6 0.38 11.0 2.6 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4690 PF15756.5 ORY44345.1 - 0.094 13.3 0.1 0.24 12.0 0.1 1.6 1 0 0 1 1 1 0 Small Novel Rich in Cartilage RCR PF12273.8 ORY44346.1 - 1.1 9.9 18.1 1.6 9.4 18.1 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red MLANA PF14991.6 ORY44348.1 - 0.093 13.0 0.0 0.16 12.2 0.0 1.5 1 1 0 1 1 1 0 Protein melan-A 7tm_7 PF08395.12 ORY44349.1 - 0.037 13.2 0.5 0.048 12.9 0.5 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor ECSCR PF15820.5 ORY44349.1 - 0.037 13.8 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Shisa PF13908.6 ORY44349.1 - 0.038 14.2 0.0 0.041 14.1 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Comm PF15957.5 ORY44349.1 - 0.054 13.8 3.3 0.14 12.5 3.3 1.7 1 1 0 1 1 1 0 Commissureless Serinc PF03348.15 ORY44349.1 - 0.057 12.3 0.0 0.057 12.3 0.0 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Adeno_GP19K PF04881.13 ORY44349.1 - 0.076 13.0 0.2 0.095 12.7 0.2 1.1 1 0 0 1 1 1 0 Adenovirus GP19K m04gp34like PF12216.8 ORY44349.1 - 0.078 12.5 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Immune evasion protein EphA2_TM PF14575.6 ORY44349.1 - 0.13 13.1 0.0 0.17 12.8 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain CD34_antigen PF06365.12 ORY44349.1 - 0.14 11.7 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family LST1 PF05083.13 ORY44349.1 - 0.14 12.5 0.2 0.83 10.0 0.2 2.1 1 1 0 1 1 1 0 LST-1 protein Amnionless PF14828.6 ORY44349.1 - 0.18 10.6 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF4881 PF16222.5 ORY44350.1 - 0.087 12.7 0.2 0.12 12.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4881) Arginase PF00491.21 ORY44352.1 - 2.2e-54 184.8 0.1 3.9e-54 184.1 0.1 1.4 1 0 0 1 1 1 1 Arginase family zf-CCHC_6 PF15288.6 ORY44354.1 - 0.11 12.3 1.9 0.25 11.2 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle Glyoxalase PF00903.25 ORY44355.1 - 0.0018 18.4 0.2 0.064 13.5 0.0 1.6 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Peripla_BP_1 PF00532.21 ORY44355.1 - 0.026 13.9 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family Glyoxalase_3 PF13468.6 ORY44355.1 - 0.045 13.9 0.5 0.17 12.0 0.1 2.1 2 1 1 3 3 3 0 Glyoxalase-like domain Glyoxalase_4 PF13669.6 ORY44355.1 - 0.16 12.3 0.0 0.48 10.7 0.0 1.8 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 ORY44357.1 - 1.5e-07 31.7 0.0 1.6e-07 31.5 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ORY44357.1 - 3.3e-06 27.4 0.0 0.0053 17.0 0.0 1.4 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Guanylate_kin PF00625.21 ORY44358.1 - 4.7e-45 153.5 0.0 3.6e-42 144.1 0.0 2.6 2 0 0 2 2 2 2 Guanylate kinase LRR_4 PF12799.7 ORY44358.1 - 2.6e-14 53.1 32.8 0.00031 21.1 2.7 6.0 3 1 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY44358.1 - 2.4e-10 39.6 19.7 0.17 12.0 0.2 9.0 8 1 1 9 9 9 4 Leucine Rich repeat LRR_8 PF13855.6 ORY44358.1 - 1.9e-09 37.2 23.0 0.0013 18.5 6.0 5.3 2 2 3 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 ORY44358.1 - 0.00016 21.2 9.7 0.028 13.9 1.4 2.7 1 1 1 2 2 2 2 Leucine-rich repeat AAA_18 PF13238.6 ORY44358.1 - 0.0002 21.9 0.0 0.00044 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ORY44358.1 - 0.0017 18.3 0.0 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 ORY44358.1 - 0.0051 17.0 0.0 0.031 14.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain Pkip-1 PF06878.11 ORY44358.1 - 0.032 14.3 0.9 2.2 8.4 0.1 2.5 2 0 0 2 2 2 0 Pkip-1 protein LRR_1 PF00560.33 ORY44358.1 - 3.1 8.7 22.5 55 4.9 0.1 7.8 7 2 0 7 7 7 0 Leucine Rich Repeat ADK PF00406.22 ORY44359.1 - 1.2e-60 204.0 0.0 1.5e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 ORY44359.1 - 6.1e-22 78.5 0.0 1.2e-21 77.6 0.0 1.4 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 ORY44359.1 - 2.1e-17 62.8 0.0 5.3e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 ORY44359.1 - 0.00012 22.3 0.0 0.00018 21.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY44359.1 - 0.0013 19.3 0.0 0.0021 18.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 ORY44359.1 - 0.037 13.7 0.0 0.049 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 ORY44359.1 - 0.078 13.3 0.7 1.7 8.9 0.2 2.2 1 1 1 2 2 2 0 Hydin Adenylate kinase-like domain Zeta_toxin PF06414.12 ORY44359.1 - 0.095 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin BRO1 PF03097.18 ORY44360.1 - 0.27 10.0 6.0 0.17 10.6 0.4 2.2 1 1 1 2 2 2 0 BRO1-like domain PUF PF00806.19 ORY44361.1 - 1.7e-34 115.6 0.0 6.4e-07 28.7 0.0 7.1 5 1 1 6 6 6 6 Pumilio-family RNA binding repeat DUF1397 PF07165.11 ORY44361.1 - 0.16 11.3 0.6 1.1 8.6 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1397) GTP_EFTU PF00009.27 ORY44362.1 - 1.8e-58 197.3 0.6 2.5e-58 196.8 0.6 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORY44362.1 - 9.5e-31 106.4 0.0 2.1e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ORY44362.1 - 5.7e-18 65.1 2.2 1.3e-17 64.0 2.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY44362.1 - 1.6e-05 25.0 0.1 3e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 ORY44362.1 - 0.0021 17.7 0.1 0.0021 17.7 0.1 1.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 ORY44362.1 - 0.0049 16.8 0.3 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase PduV-EutP PF10662.9 ORY44362.1 - 0.015 15.1 0.4 5 6.9 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation HSP20 PF00011.21 ORY44363.1 - 7.1e-19 67.9 0.5 2.3e-18 66.2 0.4 1.8 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORY44363.1 - 1.7e-06 27.4 0.0 7.6e-05 22.2 0.0 2.3 1 1 0 1 1 1 1 HSP20-like domain found in ArsA HAD_2 PF13419.6 ORY44364.1 - 4.6e-11 43.1 0.0 1.2e-10 41.8 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY44364.1 - 1.5e-07 31.9 0.0 3.7e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY44364.1 - 0.017 15.1 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like zf-C4H2 PF10146.9 ORY44364.1 - 0.079 13.3 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein Methyltransf_23 PF13489.6 ORY44365.1 - 2.3e-11 43.8 0.0 3.8e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY44365.1 - 2.5e-11 44.1 0.0 4.8e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY44365.1 - 4.4e-11 43.3 0.0 8.7e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY44365.1 - 2.9e-07 30.4 0.0 4.7e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 ORY44365.1 - 9.8e-05 22.0 0.0 0.00019 21.1 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_12 PF08242.12 ORY44365.1 - 0.00089 20.0 0.0 0.0015 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY44365.1 - 0.0015 17.9 0.0 0.0034 16.7 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 ORY44365.1 - 0.041 13.7 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase DUF3879 PF12995.7 ORY44366.1 - 0.011 15.4 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3879) Abhydrolase_1 PF00561.20 ORY44368.1 - 1.2e-07 31.6 0.6 1.8e-07 31.0 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY44368.1 - 5.1e-07 30.5 0.3 1.4e-06 29.1 0.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY44368.1 - 3.6e-05 23.2 0.0 7.2e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 ORY44368.1 - 0.0075 16.4 0.1 0.019 15.1 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain LCAT PF02450.15 ORY44368.1 - 0.051 12.7 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase PGAP1 PF07819.13 ORY44368.1 - 0.17 11.5 0.3 0.48 10.1 0.3 1.7 1 1 0 1 1 1 0 PGAP1-like protein Cytochrom_B_C PF00032.17 ORY44368.1 - 0.29 11.4 2.8 0.25 11.6 0.8 1.9 1 1 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD COG7 PF10191.9 ORY44369.1 - 4.2e-71 240.3 1.4 1.8e-44 152.2 0.5 2.5 2 1 0 2 2 2 2 Golgi complex component 7 (COG7) LRR_8 PF13855.6 ORY44370.1 - 2.3e-11 43.2 10.9 0.00048 19.8 0.9 3.7 3 1 0 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 ORY44370.1 - 4e-11 41.9 24.3 0.31 11.7 0.1 8.0 8 0 0 8 8 8 6 Leucine Rich Repeat LRR_4 PF12799.7 ORY44370.1 - 4.1e-11 42.9 17.4 0.00062 20.1 1.2 5.0 2 1 3 5 5 5 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY44370.1 - 1.6e-06 27.7 25.6 0.49 10.6 0.0 7.2 8 0 0 8 8 8 5 Leucine Rich repeat F-box PF00646.33 ORY44370.1 - 7.7e-05 22.5 0.2 7.7e-05 22.5 0.2 3.3 4 0 0 4 4 4 1 F-box domain F-box-like PF12937.7 ORY44370.1 - 0.0009 19.1 1.1 0.0022 17.8 0.1 2.2 2 0 0 2 2 2 1 F-box-like TIR_2 PF13676.6 ORY44371.1 - 4e-14 53.2 0.6 1.7e-11 44.8 0.0 3.1 3 0 0 3 3 3 1 TIR domain TIR PF01582.20 ORY44371.1 - 8.2e-05 22.5 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 TIR domain DUF1863 PF08937.11 ORY44371.1 - 0.00062 20.1 0.4 0.27 11.5 0.0 2.6 2 1 0 2 2 2 2 MTH538 TIR-like domain (DUF1863) PYNP_C PF07831.13 ORY44371.1 - 0.17 11.6 0.0 13 5.6 0.0 2.4 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain Ank_2 PF12796.7 ORY44372.1 - 9e-16 58.2 0.5 1.1e-08 35.6 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY44372.1 - 6.5e-12 45.7 0.2 1.2e-06 29.0 0.1 2.8 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY44372.1 - 1.4e-07 31.2 0.1 2.4 9.0 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 ORY44372.1 - 1.8e-06 28.1 0.0 1.2 9.7 0.2 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 ORY44372.1 - 1.9e-06 28.0 0.5 0.41 11.0 0.0 3.7 2 1 2 4 4 4 3 Ankyrin repeats (many copies) DUF1724 PF08350.10 ORY44372.1 - 0.08 13.1 0.5 1.2 9.3 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1724) RNase_P_p30 PF01876.16 ORY44372.1 - 0.089 12.2 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 RNase P subunit p30 AMP-binding PF00501.28 ORY44373.1 - 7.8e-36 123.6 0.8 1.4e-21 76.6 0.1 2.6 2 1 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 ORY44373.1 - 1.3e-12 48.5 0.1 3e-12 47.3 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thioredoxin PF00085.20 ORY44375.1 - 1.4e-11 44.2 0.0 2.6e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY44375.1 - 0.006 17.0 0.0 0.015 15.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 ORY44375.1 - 0.015 15.3 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.10 ORY44375.1 - 0.16 11.7 0.0 0.43 10.3 0.0 1.7 2 0 0 2 2 2 0 Redoxin NAD_binding_10 PF13460.6 ORY44376.1 - 2.9e-19 69.7 0.8 3.9e-18 66.0 0.8 1.9 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY44376.1 - 2.1e-10 40.6 0.6 9.2e-10 38.5 0.5 2.0 1 1 1 2 2 2 1 NmrA-like family Epimerase PF01370.21 ORY44376.1 - 4.4e-07 29.6 1.4 8.9e-06 25.3 0.1 2.6 1 1 2 3 3 3 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 ORY44376.1 - 2.3e-06 27.2 0.4 2.3e-05 23.9 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.19 ORY44376.1 - 0.00022 20.4 0.7 0.00056 19.0 0.7 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 ORY44376.1 - 0.00024 21.4 0.2 0.00041 20.6 0.2 1.5 1 0 0 1 1 1 1 TrkA-N domain DapB_N PF01113.20 ORY44376.1 - 0.0013 18.9 0.3 0.0018 18.4 0.3 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_2 PF03446.15 ORY44376.1 - 0.003 17.8 0.3 0.0044 17.2 0.1 1.4 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.10 ORY44376.1 - 0.0045 16.9 0.6 0.0072 16.3 0.6 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 ORY44376.1 - 0.0058 15.8 0.3 0.01 15.0 0.3 1.4 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 ORY44376.1 - 0.026 13.6 0.7 0.12 11.5 0.7 2.0 1 1 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ORY44376.1 - 0.059 12.5 0.1 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein HSP20 PF00011.21 ORY44377.1 - 1.4e-26 92.6 0.9 1.9e-26 92.2 0.9 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORY44377.1 - 2.8e-11 42.8 0.0 6.6e-11 41.6 0.0 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA FKBP26_C PF18046.1 ORY44377.1 - 0.0062 16.6 0.4 0.047 13.8 0.1 2.0 2 0 0 2 2 2 1 FKBP26_C-terminal CS PF04969.16 ORY44377.1 - 0.015 16.3 0.0 0.02 15.9 0.0 1.2 1 0 0 1 1 1 0 CS domain GvpH PF05455.11 ORY44377.1 - 0.039 14.0 0.1 0.11 12.6 0.0 1.7 1 1 0 1 1 1 0 GvpH DEAD PF00270.29 ORY44378.1 - 1.8e-27 96.2 0.2 5.5e-12 45.8 0.0 4.0 2 1 1 3 3 3 3 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY44378.1 - 4e-26 91.5 0.0 9.9e-26 90.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FliS PF02561.14 ORY44378.1 - 0.082 13.2 0.7 0.28 11.5 0.9 1.8 2 0 0 2 2 2 0 Flagellar protein FliS DUF4821 PF16092.5 ORY44379.1 - 1.5e-28 100.2 0.1 4.2e-17 62.6 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4821) DUF5522 PF17653.1 ORY44379.1 - 3.6 7.6 8.5 7.1 6.7 8.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5522) HLH PF00010.26 ORY44380.1 - 4.9e-09 36.0 0.0 1.1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pyr_redox_2 PF07992.14 ORY44380.1 - 0.0013 18.0 0.0 0.25 10.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SUIM_assoc PF16619.5 ORY44380.1 - 0.015 15.3 3.8 0.047 13.8 3.8 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Pyr_redox PF00070.27 ORY44380.1 - 0.077 13.6 0.0 25 5.5 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TFIIA PF03153.13 ORY44380.1 - 0.26 11.2 13.8 0.36 10.8 13.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PGA2 PF07543.12 ORY44380.1 - 5.2 7.0 8.4 10 6.1 8.4 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 zf-B_box PF00643.24 ORY44381.1 - 7.3e-15 54.8 18.0 9.9e-08 32.0 7.3 2.3 2 0 0 2 2 2 2 B-box zinc finger DUF445 PF04286.12 ORY44381.1 - 0.016 15.0 1.4 0.026 14.3 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) PARP PF00644.20 ORY44381.1 - 0.056 13.0 0.9 0.34 10.5 0.9 2.3 1 1 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain ATP-synt_B PF00430.18 ORY44381.1 - 0.06 13.4 7.8 0.051 13.7 4.9 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) LMBR1 PF04791.16 ORY44381.1 - 0.093 11.6 0.3 0.12 11.2 0.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein MCD_N PF17408.2 ORY44381.1 - 0.16 12.1 0.7 0.34 11.1 0.7 1.5 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase N-terminal domain DUF1664 PF07889.12 ORY44381.1 - 0.29 11.2 2.8 0.77 9.8 2.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zinc-ribbons_6 PF07191.12 ORY44381.1 - 5.1 7.1 10.9 1.4 9.0 2.5 2.4 2 0 0 2 2 2 0 zinc-ribbons RNHCP PF12647.7 ORY44381.1 - 6 6.9 12.8 16 5.5 12.9 1.7 1 1 0 1 1 1 0 RNHCP domain MlaA PF04333.13 ORY44382.1 - 0.021 14.5 0.0 0.036 13.8 0.0 1.3 1 0 0 1 1 1 0 MlaA lipoprotein DUF4699 PF15770.5 ORY44382.1 - 0.092 12.5 0.6 0.13 12.0 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) Glyco_transf_8 PF01501.20 ORY44383.1 - 0.037 13.6 0.1 0.085 12.4 0.1 1.7 1 1 0 1 1 1 0 Glycosyl transferase family 8 Competence PF03772.16 ORY44384.1 - 0.076 12.3 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Competence protein DBR1 PF05011.13 ORY44385.1 - 8e-18 65.2 0.0 1.7e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 ORY44385.1 - 2.4e-09 38.0 3.6 3.4e-09 37.5 3.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3336 PF11815.8 ORY44386.1 - 1.5e-30 105.7 0.0 5.4e-30 103.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 ORY44386.1 - 1.1e-18 68.2 0.0 2.5e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Peptidase_S51 PF03575.17 ORY44386.1 - 0.016 14.8 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase family S51 Brix PF04427.18 ORY44387.1 - 6.6e-24 85.1 0.1 9.2e-24 84.6 0.1 1.2 1 0 0 1 1 1 1 Brix domain MMACHC PF16690.5 ORY44388.1 - 2e-06 27.6 0.1 1.1e-05 25.3 0.1 1.8 1 1 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family FAD_binding_3 PF01494.19 ORY44389.1 - 1.8e-18 66.9 0.0 5e-08 32.6 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 ORY44389.1 - 2.3e-05 23.6 0.0 0.0033 16.5 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.24 ORY44389.1 - 3.4e-05 23.6 0.0 6.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY44389.1 - 0.0024 17.2 0.1 0.018 14.3 0.1 1.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 ORY44389.1 - 0.0026 16.9 0.0 0.0045 16.1 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.14 ORY44389.1 - 0.008 15.1 0.3 0.031 13.1 0.2 2.0 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.6 ORY44389.1 - 0.0082 16.3 1.2 0.018 15.3 1.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY44389.1 - 0.016 15.7 0.0 0.044 14.4 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY44389.1 - 0.049 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Mito_carr PF00153.27 ORY44390.1 - 3.5e-19 68.5 0.0 1.7e-07 31.1 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DDE_Tnp_1_3 PF13612.6 ORY44390.1 - 0.14 12.1 0.0 0.45 10.5 0.0 1.7 2 0 0 2 2 2 0 Transposase DDE domain ParA PF10609.9 ORY44391.1 - 4.9e-90 301.3 3.2 6.1e-90 301.0 3.2 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 ORY44391.1 - 9.5e-14 51.6 0.0 4.4e-13 49.4 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 ORY44391.1 - 2.8e-13 50.2 0.9 3.4e-10 40.1 0.1 2.2 2 0 0 2 2 2 2 AAA domain Fer4_NifH PF00142.18 ORY44391.1 - 2.3e-07 30.6 0.0 0.00056 19.4 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 ORY44391.1 - 1.1e-06 28.2 0.2 2.2e-06 27.1 0.2 1.6 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 ORY44391.1 - 0.00011 21.6 3.5 0.0058 15.9 3.0 2.8 1 1 1 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 ORY44391.1 - 0.0012 18.2 0.1 0.0021 17.4 0.1 1.4 1 0 0 1 1 1 1 VirC1 protein AAA_26 PF13500.6 ORY44391.1 - 0.0035 17.2 2.9 0.22 11.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain CLP1_P PF16575.5 ORY44391.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SIKE PF05769.11 ORY44392.1 - 1.4e-06 28.4 11.0 2.9e-06 27.3 11.0 1.5 1 1 0 1 1 1 1 SIKE family Lipase_chap PF03280.14 ORY44392.1 - 0.014 15.3 2.5 0.014 15.3 2.5 2.1 2 0 0 2 2 2 0 Proteobacterial lipase chaperone protein DUF2220 PF09983.9 ORY44392.1 - 0.016 14.6 0.5 0.029 13.7 0.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) Rootletin PF15035.6 ORY44392.1 - 0.4 10.7 12.2 1 9.3 3.9 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Cnn_1N PF07989.11 ORY44392.1 - 3.5 7.9 8.9 13 6.0 0.7 2.5 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 p450 PF00067.22 ORY44394.1 - 5.1e-21 75.0 0.0 6.7e-10 38.3 0.0 3.0 1 1 2 3 3 3 3 Cytochrome P450 CBM32 PF18344.1 ORY44395.1 - 0.037 13.9 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding module family 32 Acetyltransf_1 PF00583.25 ORY44395.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Mito_carr PF00153.27 ORY44396.1 - 1.5e-11 44.0 0.0 1.1e-06 28.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 ORY44397.1 - 8.8e-06 25.6 0.2 0.059 13.3 0.1 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein SYS1 PF09801.9 ORY44399.1 - 2.8e-23 82.7 5.2 3.3e-23 82.4 5.2 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network PI3Ka PF00613.20 ORY44400.1 - 2.8e-37 127.9 0.3 4.2e-36 124.1 0.3 2.4 1 1 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 ORY44400.1 - 4.4e-37 127.1 0.0 7.2e-37 126.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3_PI4_kinase PF00454.27 ORY44400.1 - 2.1e-12 47.4 0.5 3.8e-09 36.7 0.0 2.6 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase BT1 PF03092.16 ORY44401.1 - 1.8e-57 194.8 10.0 1.3e-33 116.0 1.4 3.0 2 2 1 3 3 3 2 BT1 family DUF1889 PF08986.10 ORY44401.1 - 0.15 12.4 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1889) Acetyltransf_3 PF13302.7 ORY44402.1 - 1.8e-18 67.5 0.0 2.2e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY44402.1 - 1.4e-07 31.8 0.0 1.8e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 ORY44402.1 - 2.3e-06 27.8 0.0 3.4e-06 27.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY44402.1 - 0.032 14.7 0.0 0.054 13.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ORY44402.1 - 0.039 13.6 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_M14 PF00246.24 ORY44403.1 - 1.4e-64 218.7 0.0 1.7e-64 218.4 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.16 ORY44403.1 - 2.1e-05 24.8 0.1 4.6e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Carboxypeptidase activation peptide RNA_lig_T4_1 PF09511.10 ORY44404.1 - 1.4e-66 224.5 0.0 2.2e-66 223.9 0.0 1.3 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 ORY44404.1 - 2e-13 50.8 0.0 4.2e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain Ubiq_cyt_C_chap PF03981.12 ORY44405.1 - 2.1e-29 102.4 0.1 2.6e-29 102.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone MFS_1 PF07690.16 ORY44406.1 - 1.6e-16 60.2 60.5 9.9e-09 34.6 29.8 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 ORY44407.1 - 5.7e-08 32.1 30.0 4.2e-07 29.2 30.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2614 PF11023.8 ORY44407.1 - 7.9 6.6 7.5 0.41 10.8 1.6 1.8 2 0 0 2 2 2 0 Zinc-ribbon containing domain MFS_1 PF07690.16 ORY44408.1 - 5.5e-12 45.3 56.0 3e-08 33.0 20.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ADK PF00406.22 ORY44410.1 - 1.9e-49 167.7 0.0 2.7e-48 163.9 0.0 2.1 2 0 0 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 ORY44410.1 - 2.2e-33 115.6 0.2 4e-32 111.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY44410.1 - 4.6e-08 33.7 0.0 6.5e-07 30.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORY44410.1 - 6.4e-05 23.2 0.0 0.00076 19.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 ORY44410.1 - 0.00033 21.0 0.4 0.91 9.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF5582 PF17819.1 ORY44410.1 - 0.00055 20.4 0.0 0.001 19.5 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5582) AAA_16 PF13191.6 ORY44410.1 - 0.0018 18.7 0.0 1.1 9.6 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Cytidylate_kin PF02224.18 ORY44410.1 - 0.002 17.9 0.0 0.016 14.9 0.0 2.1 2 0 0 2 2 2 1 Cytidylate kinase Zeta_toxin PF06414.12 ORY44410.1 - 0.004 16.4 0.0 0.12 11.7 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.6 ORY44410.1 - 0.0042 17.3 0.4 1.4 9.2 0.1 2.6 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 ORY44410.1 - 0.0043 17.0 0.0 0.16 11.8 0.0 2.3 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 Thymidylate_kin PF02223.17 ORY44410.1 - 0.0087 15.8 0.5 0.61 9.7 0.0 2.7 3 0 0 3 3 3 1 Thymidylate kinase DUF5586 PF17824.1 ORY44410.1 - 0.01 15.0 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5586) AAA PF00004.29 ORY44410.1 - 0.015 15.8 0.1 3.6 8.0 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 ORY44410.1 - 0.035 13.8 0.1 6.8 6.4 0.1 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 ORY44410.1 - 0.037 14.3 0.2 0.91 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain ADK PF00406.22 ORY44411.1 - 8.2e-251 821.3 0.0 2.5e-44 151.0 0.0 6.1 6 0 0 6 6 6 6 Adenylate kinase AAA_17 PF13207.6 ORY44411.1 - 1.9e-179 588.5 4.2 4e-31 108.2 0.0 6.1 6 0 0 6 6 6 6 AAA domain AAA_18 PF13238.6 ORY44411.1 - 3.4e-40 137.6 0.0 1.2e-05 25.9 0.0 6.6 6 0 0 6 6 6 6 AAA domain AAA_33 PF13671.6 ORY44411.1 - 5.5e-23 81.7 16.8 0.04 14.1 0.1 10.6 7 4 0 7 7 7 7 AAA domain Cytidylate_kin PF02224.18 ORY44411.1 - 1.7e-20 73.7 0.3 0.22 11.3 0.0 6.2 6 0 0 6 6 6 6 Cytidylate kinase Ploopntkinase3 PF18751.1 ORY44411.1 - 4.3e-19 69.2 0.1 0.3 11.0 0.0 6.2 6 0 0 6 6 6 6 P-loop Nucleotide Kinase3 Hydin_ADK PF17213.3 ORY44411.1 - 2.8e-15 57.1 0.0 0.22 11.8 0.0 6.2 6 0 0 6 6 6 5 Hydin Adenylate kinase-like domain AAA_19 PF13245.6 ORY44411.1 - 4.7e-13 49.7 7.1 1.7 9.0 0.0 6.3 6 0 0 6 6 6 5 AAA domain Zeta_toxin PF06414.12 ORY44411.1 - 4.8e-13 48.8 0.5 2.2 7.5 0.0 6.4 6 0 0 6 6 6 4 Zeta toxin SRP54 PF00448.22 ORY44411.1 - 1.4e-12 47.7 0.5 2.3 7.8 0.0 6.3 6 0 0 6 6 6 2 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.17 ORY44411.1 - 2e-08 34.1 19.7 3.7 7.2 0.1 9.7 10 1 0 10 10 10 1 Thymidylate kinase Prot_ATP_ID_OB PF16450.5 ORY44411.1 - 1.6e-07 31.1 0.6 25 4.9 0.0 6.6 6 1 0 6 6 6 0 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 ORY44411.1 - 5e-07 30.1 7.8 22 5.3 0.1 6.6 6 0 0 6 6 6 0 AAA domain GATase PF00117.28 ORY44411.1 - 7.5e-07 29.1 0.2 20 4.8 0.0 6.0 6 0 0 6 6 6 0 Glutamine amidotransferase class-I DUF2075 PF09848.9 ORY44411.1 - 1.1e-06 28.1 3.0 21 4.2 0.0 6.0 6 0 0 6 6 6 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 ORY44411.1 - 5.8e-06 26.8 7.0 50 4.3 0.0 6.9 6 0 0 6 6 6 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY44411.1 - 6e-06 26.8 9.9 5.1 7.4 0.0 6.3 6 0 0 6 6 6 1 AAA ATPase domain Thermopsin PF05317.11 ORY44411.1 - 8.8e-06 25.4 0.0 37 3.7 0.0 5.8 6 0 0 6 6 6 0 Thermopsin MIR PF02815.19 ORY44411.1 - 1.8e-05 24.7 0.0 33 4.3 0.0 5.6 6 0 0 6 6 6 0 MIR domain DUF1830 PF08865.11 ORY44411.1 - 1.8e-05 24.6 8.2 5.7 7.0 0.1 5.3 5 0 0 5 5 5 0 Domain of unknown function (DUF1830) Viral_helicase1 PF01443.18 ORY44411.1 - 2.1e-05 24.4 16.6 10 5.8 0.1 6.2 6 0 0 6 6 6 0 Viral (Superfamily 1) RNA helicase DUF4817 PF16087.5 ORY44411.1 - 2.4e-05 24.0 1.8 45 4.0 0.0 5.6 6 0 0 6 6 6 0 Helix-turn-helix domain (DUF4817) Ploopntkinase2 PF18747.1 ORY44411.1 - 4.3e-05 22.9 2.8 33 3.6 0.0 6.3 6 0 0 6 6 6 0 P-loop Nucleotide Kinase2 Rad17 PF03215.15 ORY44411.1 - 0.00018 21.5 3.0 30 4.5 0.0 5.6 6 0 0 6 6 6 0 Rad17 P-loop domain ASPRs PF17641.2 ORY44411.1 - 0.00023 21.4 0.0 20 5.5 0.0 4.9 5 0 0 5 5 5 0 Ancylostoma-associated secreted protein related ATP_bind_1 PF03029.17 ORY44411.1 - 0.0003 20.7 16.0 13 5.4 0.1 6.1 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 ORY44411.1 - 0.0006 20.1 15.9 33 4.7 0.1 6.2 6 0 0 6 6 6 0 AAA domain KTI12 PF08433.10 ORY44411.1 - 0.0016 17.9 3.9 39 3.6 0.0 5.8 6 0 0 6 6 6 0 Chromatin associated protein KTI12 RNA_helicase PF00910.22 ORY44411.1 - 0.011 16.2 4.7 2.5e+02 2.1 0.0 5.9 6 0 0 6 6 6 0 RNA helicase NTPase_1 PF03266.15 ORY44411.1 - 0.011 15.6 15.1 18 5.2 0.1 6.2 6 0 0 6 6 6 0 NTPase DUF1477 PF07346.11 ORY44411.1 - 0.026 14.8 0.2 1.3e+02 2.8 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1477) UvrD-helicase PF00580.21 ORY44411.1 - 0.036 13.6 0.7 1.8e+02 1.4 0.0 5.1 6 0 0 6 6 6 0 UvrD/REP helicase N-terminal domain MutL PF13941.6 ORY44411.1 - 0.16 10.5 0.1 55 2.2 0.0 4.1 5 0 0 5 5 5 0 MutL protein Cys_Met_Meta_PP PF01053.20 ORY44412.1 - 3.3e-142 473.5 0.0 4.4e-142 473.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 ORY44412.1 - 2.3e-10 40.0 0.3 3.6e-10 39.3 0.3 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 ORY44412.1 - 3.5e-10 39.6 0.0 4.8e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ORY44412.1 - 3.4e-09 36.5 0.1 6.3e-09 35.6 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 ORY44412.1 - 8e-06 25.3 0.0 2.5e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase SepSecS PF05889.13 ORY44412.1 - 0.0019 17.0 0.0 0.0031 16.3 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS GDC-P PF02347.16 ORY44412.1 - 0.0024 16.8 0.0 0.0035 16.2 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.11 ORY44412.1 - 0.012 14.2 0.1 0.017 13.7 0.1 1.3 1 0 0 1 1 1 0 Methionine gamma-lyase SPRY PF00622.28 ORY44413.1 - 3.5e-27 94.9 0.1 4.8e-27 94.5 0.1 1.2 1 0 0 1 1 1 1 SPRY domain AtuA PF07287.11 ORY44416.1 - 1.7e-54 184.9 0.1 2.1e-54 184.6 0.1 1.0 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA His_Phos_2 PF00328.22 ORY44417.1 - 0.022 14.1 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Topoisom_I_N PF02919.15 ORY44417.1 - 0.023 14.2 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment OCIA PF07051.11 ORY44417.1 - 0.16 12.0 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Ovarian carcinoma immunoreactive antigen (OCIA) WD40 PF00400.32 ORY44418.1 - 2.4e-10 40.8 2.1 1 10.4 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Nop53 PF07767.11 ORY44419.1 - 5.8e-62 210.3 24.5 2.6e-45 155.5 15.4 2.1 1 1 1 2 2 2 2 Nop53 (60S ribosomal biogenesis) PRAS PF15798.5 ORY44419.1 - 0.026 15.1 2.6 0.15 12.7 1.2 2.4 2 0 0 2 2 2 0 Proline-rich AKT1 substrate 1 Aldo_ket_red PF00248.21 ORY44420.1 - 1.1e-46 159.4 0.0 4.6e-46 157.4 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Hydrolase_4 PF12146.8 ORY44421.1 - 1.6e-46 158.5 0.0 1.9e-46 158.3 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY44421.1 - 6.4e-07 30.2 0.0 6.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 ORY44421.1 - 5.7e-06 26.3 0.5 1.5 8.6 0.0 3.1 3 0 0 3 3 3 3 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 ORY44421.1 - 0.00012 21.8 0.2 0.0011 18.7 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY44421.1 - 0.006 16.1 0.1 1.5 8.2 0.0 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family AXE1 PF05448.12 ORY44421.1 - 0.012 14.3 0.4 0.032 12.9 0.4 1.7 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Thioesterase PF00975.20 ORY44421.1 - 0.02 15.0 0.0 0.034 14.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain OpuAC PF04069.12 ORY44422.1 - 9.7e-14 51.6 0.0 6.8e-06 25.8 0.0 2.1 2 0 0 2 2 2 2 Substrate binding domain of ABC-type glycine betaine transport system Furin-like_2 PF15913.5 ORY44422.1 - 9.3 6.5 12.7 22 5.3 6.5 2.3 2 0 0 2 2 2 0 Furin-like repeat, cysteine-rich HTH_21 PF13276.6 ORY44424.1 - 0.1 12.7 0.1 2.1 8.6 0.0 2.5 2 0 0 2 2 2 0 HTH-like domain HTH_33 PF13592.6 ORY44424.1 - 0.2 11.3 1.4 2.5 7.8 0.1 2.6 2 0 0 2 2 2 0 Winged helix-turn helix WD40 PF00400.32 ORY44426.1 - 3e-06 27.8 0.0 3.8 8.5 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat eIF2A PF08662.11 ORY44426.1 - 1.4e-05 25.1 0.1 0.0079 16.1 0.0 3.5 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A DUF3844 PF12955.7 ORY44427.1 - 1.1e-24 86.5 2.3 2e-24 85.7 2.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_2 PF07974.13 ORY44427.1 - 4.8 7.7 8.9 14 6.2 8.9 1.8 1 0 0 1 1 1 0 EGF-like domain WD40 PF00400.32 ORY44428.1 - 1.2e-46 155.7 14.5 2.9e-07 31.0 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY44428.1 - 9e-17 61.2 0.2 0.0032 17.7 0.0 5.4 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY44428.1 - 4.8e-08 32.3 0.5 0.018 14.0 0.0 4.6 1 1 3 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 ORY44428.1 - 3.7e-05 23.6 1.0 0.0011 18.8 0.0 2.7 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.6 ORY44428.1 - 0.02 14.5 0.6 0.16 11.5 0.2 2.4 2 1 0 2 2 2 0 PQQ-like domain Frtz PF11768.8 ORY44428.1 - 0.044 12.1 0.0 0.88 7.8 0.0 2.4 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 ORY44428.1 - 0.088 12.8 2.7 41 4.3 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.6 ORY44428.1 - 0.098 13.2 0.1 1.8 9.1 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain Nucleoporin_N PF08801.11 ORY44428.1 - 0.11 11.2 0.2 0.65 8.7 0.0 2.3 2 2 0 2 2 2 0 Nup133 N terminal like Cytochrom_C552 PF02335.15 ORY44428.1 - 0.17 10.8 0.1 0.23 10.3 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c552 SesA PF17107.5 ORY44429.1 - 0.016 15.4 0.9 0.016 15.4 0.9 3.3 4 0 0 4 4 4 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DASH_Hsk3 PF08227.11 ORY44429.1 - 0.065 13.6 0.6 60 4.1 0.0 3.9 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like NPV_P10 PF05531.12 ORY44429.1 - 2.6 8.6 13.7 9.9 6.7 0.8 4.1 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF2730 PF10805.8 ORY44429.1 - 3.4 7.8 30.6 0.17 12.0 1.4 5.2 2 2 3 6 6 6 0 Protein of unknown function (DUF2730) SF3b1 PF08920.10 ORY44430.1 - 9.8e-42 142.2 4.1 9.8e-42 142.2 4.1 3.3 1 1 2 3 3 3 2 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 ORY44430.1 - 2.1e-11 44.0 0.4 0.23 12.0 0.0 6.9 8 1 1 9 9 8 3 HEAT-like repeat HEAT PF02985.22 ORY44430.1 - 6.6e-10 38.4 2.1 5.9 7.4 0.1 8.9 10 0 0 10 10 10 2 HEAT repeat HEAT_2 PF13646.6 ORY44430.1 - 1.2e-09 38.5 1.7 0.17 12.3 0.0 7.4 5 2 2 7 7 7 3 HEAT repeats DUF3385 PF11865.8 ORY44430.1 - 0.00016 21.6 4.9 0.34 10.8 0.1 5.4 4 2 0 5 5 5 1 Domain of unknown function (DUF3385) Dopey_N PF04118.14 ORY44430.1 - 0.00087 18.5 1.9 0.35 9.9 0.0 3.9 3 1 0 4 4 4 1 Dopey, N-terminal Cnd1 PF12717.7 ORY44430.1 - 0.0014 18.7 7.2 1 9.4 0.1 5.6 6 1 1 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 ORY44430.1 - 0.0041 15.7 2.6 0.26 9.8 0.0 3.3 3 2 0 3 3 3 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 ORY44430.1 - 0.009 16.6 2.0 7 7.3 0.0 4.5 5 0 0 5 5 4 1 Vacuolar 14 Fab1-binding region NUC173 PF08161.12 ORY44430.1 - 0.035 13.8 0.6 7.4 6.2 0.0 4.6 3 2 1 5 5 5 0 NUC173 domain MMS19_C PF12460.8 ORY44430.1 - 0.082 12.0 0.0 17 4.4 0.0 3.2 2 1 0 2 2 2 0 RNAPII transcription regulator C-terminal UNC45-central PF11701.8 ORY44430.1 - 0.087 12.8 0.2 0.38 10.7 0.0 2.2 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central DNA_pol_phi PF04931.13 ORY44430.1 - 0.093 10.8 0.0 0.093 10.8 0.0 3.0 3 0 0 3 3 2 0 DNA polymerase phi Arm PF00514.23 ORY44430.1 - 0.13 12.3 0.6 41 4.4 0.0 4.5 6 0 0 6 6 5 0 Armadillo/beta-catenin-like repeat EGF PF00008.27 ORY44431.1 - 0.43 10.9 0.3 0.43 10.9 0.3 3.3 3 0 0 3 3 3 0 EGF-like domain ABC2_membrane PF01061.24 ORY44432.1 - 4.2e-31 108.0 16.0 7.9e-31 107.1 16.0 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 ORY44432.1 - 3.8e-28 98.7 0.0 6.1e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY44432.1 - 1.8e-05 24.7 1.5 0.14 11.9 0.1 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY44432.1 - 0.00072 19.3 0.2 0.0016 18.1 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY44432.1 - 0.001 19.0 0.1 0.0022 17.9 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 ORY44432.1 - 0.0067 16.0 0.0 0.026 14.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY44432.1 - 0.024 15.2 0.0 0.05 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 ORY44432.1 - 0.051 13.5 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_33 PF13671.6 ORY44432.1 - 0.13 12.4 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ORY44432.1 - 0.14 12.7 0.1 0.25 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY44432.1 - 0.19 11.4 0.7 0.84 9.3 0.2 2.0 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 ORY44432.1 - 0.29 10.5 0.5 9 5.7 0.3 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain PDR_assoc PF08370.11 ORY44432.1 - 0.85 9.4 3.9 2.1 8.2 0.1 2.6 2 0 0 2 2 2 0 Plant PDR ABC transporter associated SYF2 PF08231.12 ORY44433.1 - 3.7e-44 150.9 15.0 3.7e-44 150.9 15.0 2.0 2 0 0 2 2 2 1 SYF2 splicing factor DUF2813 PF11398.8 ORY44433.1 - 0.094 12.0 5.0 0.19 10.9 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2813) Peptidase_M57 PF12388.8 ORY44433.1 - 0.12 12.0 0.7 0.18 11.4 0.5 1.3 1 1 0 1 1 1 0 Dual-action HEIGH metallo-peptidase SR-25 PF10500.9 ORY44434.1 - 2.4 7.7 35.6 0.042 13.5 27.1 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Peptidase_M1 PF01433.20 ORY44436.1 - 8.4e-15 54.9 0.2 2.8e-14 53.2 0.2 1.9 1 1 0 1 1 1 1 Peptidase family M1 domain HEAT_2 PF13646.6 ORY44436.1 - 0.065 13.6 0.0 0.41 11.1 0.0 2.2 2 0 0 2 2 2 0 HEAT repeats Hamartin PF04388.12 ORY44437.1 - 0.18 10.5 0.0 0.18 10.5 0.0 1.3 2 0 0 2 2 2 0 Hamartin protein Med12-LCEWAV PF12145.8 ORY44439.1 - 0.0033 16.4 0.0 0.0062 15.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain Na_sulph_symp PF00939.19 ORY44440.1 - 7.8e-73 246.1 29.4 9.3e-73 245.9 29.4 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 ORY44440.1 - 4.4e-08 32.7 26.9 4.4e-08 32.7 26.9 2.2 1 1 1 2 2 2 2 Citrate transporter ANF_receptor PF01094.28 ORY44441.1 - 1.8e-23 83.3 0.0 2.5e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY44441.1 - 4.2e-06 26.7 0.0 1.3e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Periplasmic binding protein 7tm_3 PF00003.22 ORY44442.1 - 1.1e-05 25.3 13.5 1.7e-05 24.7 13.5 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR MnhB PF04039.13 ORY44442.1 - 0.93 9.8 8.0 1.3 9.4 5.0 2.3 1 1 1 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter Polysacc_synt_C PF14667.6 ORY44442.1 - 4.4 7.4 13.5 0.7 9.9 6.0 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain RPAP1_C PF08620.10 ORY44443.1 - 4e-09 36.5 0.1 1.1e-08 35.0 0.1 1.8 1 0 0 1 1 1 1 RPAP1-like, C-terminal ANF_receptor PF01094.28 ORY44444.1 - 3.6e-16 59.2 0.0 4.9e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY44444.1 - 4.8e-05 23.2 0.0 0.00024 20.9 0.0 1.8 1 1 0 1 1 1 1 Periplasmic binding protein MMS19_N PF14500.6 ORY44446.1 - 2.8e-48 164.8 0.0 3e-48 164.7 0.0 1.0 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II DUF1324 PF07038.11 ORY44446.1 - 0.0056 16.9 0.1 0.7 10.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1324) RNA_pol_Rpb2_2 PF04561.14 ORY44447.1 - 0.003 17.2 0.0 0.0042 16.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 TrbC PF04956.13 ORY44447.1 - 0.034 14.4 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 TrbC/VIRB2 family DUF982 PF06169.12 ORY44447.1 - 0.042 13.9 0.3 2.2 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF982) MMS19_C PF12460.8 ORY44448.1 - 1.2e-14 54.3 0.3 1.5e-14 54.0 0.3 1.0 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal LIAS_N PF16881.5 ORY44449.1 - 3e-22 79.1 0.3 8.1e-22 77.7 0.3 1.7 1 1 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 ORY44449.1 - 8.5e-10 39.3 0.1 3.2e-09 37.4 0.1 2.0 1 1 0 1 1 1 1 Radical SAM superfamily HMG-CoA_red PF00368.18 ORY44450.1 - 1.5e-146 488.2 6.1 2e-146 487.7 6.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.8 ORY44450.1 - 1.3e-06 28.3 6.6 2.8e-06 27.2 6.6 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation HPIH PF13323.6 ORY44450.1 - 0.18 11.7 3.0 0.43 10.4 3.0 1.6 1 0 0 1 1 1 0 N-terminal domain with HPIH motif PCI PF01399.27 ORY44451.1 - 5.7e-17 62.1 1.4 8.4e-17 61.6 0.4 1.8 2 0 0 2 2 2 1 PCI domain ACDC PF14733.6 ORY44451.1 - 0.067 13.5 0.2 0.37 11.1 0.0 2.2 2 0 0 2 2 2 0 AP2-coincident C-terminal PAS_3 PF08447.12 ORY44452.1 - 1.4e-07 31.7 0.0 3.8e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.6 ORY44452.1 - 9.5e-06 25.7 0.0 4.4e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 ORY44452.1 - 1.7e-05 24.8 0.0 0.0015 18.5 0.0 2.3 2 1 0 2 2 2 1 PAS fold PAS_4 PF08448.10 ORY44452.1 - 0.057 13.7 0.0 0.48 10.7 0.0 2.1 2 1 0 2 2 2 0 PAS fold PAS_9 PF13426.7 ORY44452.1 - 0.059 13.6 0.0 0.69 10.2 0.0 2.1 2 0 0 2 2 2 0 PAS domain Pkinase PF00069.25 ORY44453.1 - 7.2e-06 25.5 0.0 8.6e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY44453.1 - 0.0063 15.8 0.1 0.008 15.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORY44454.1 - 2.3e-14 53.4 0.0 2.5e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY44454.1 - 1.5e-09 37.5 0.0 1.6e-09 37.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Septin PF00735.18 ORY44455.1 - 6.6e-78 261.8 0.7 7.6e-78 261.6 0.7 1.1 1 0 0 1 1 1 1 Septin SDA1 PF05285.12 ORY44456.1 - 0.018 14.5 27.0 0.021 14.3 27.0 1.0 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 ORY44456.1 - 0.27 9.4 28.2 0.32 9.2 28.2 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 ORY44456.1 - 0.3 10.4 20.4 0.35 10.2 20.4 1.1 1 0 0 1 1 1 0 BUD22 Dynactin_p62 PF05502.13 ORY44456.1 - 1.3 7.7 4.2 1.8 7.3 4.2 1.1 1 0 0 1 1 1 0 Dynactin p62 family Merozoite_SPAM PF07133.11 ORY44456.1 - 8.4 6.3 38.0 2.4 8.1 27.7 2.1 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) RF-1 PF00472.20 ORY44458.1 - 4.4e-13 49.2 0.1 4.8e-13 49.1 0.1 1.0 1 0 0 1 1 1 1 RF-1 domain DUF705 PF05152.12 ORY44458.1 - 0.049 13.1 0.1 0.056 12.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF705) MOR2-PAG1_N PF14222.6 ORY44459.1 - 5.3e-107 359.0 2.2 1.1e-86 292.0 4.2 2.6 2 0 0 2 2 2 2 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 ORY44459.1 - 1e-48 166.4 1.1 1e-48 166.4 1.1 2.8 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 ORY44459.1 - 6e-20 70.6 2.5 7e-11 40.6 0.1 4.9 3 1 1 4 4 4 4 Cell morphogenesis central region SPO22 PF08631.10 ORY44459.1 - 0.087 12.3 2.8 3 7.2 0.0 3.2 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like Kinesin PF00225.23 ORY44460.1 - 1.8e-66 224.4 0.4 2.5e-66 223.9 0.4 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY44460.1 - 3.1e-10 40.2 0.0 6.5e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding CHASE3 PF05227.13 ORY44460.1 - 0.005 16.7 0.8 0.005 16.7 0.8 2.0 2 0 0 2 2 2 1 CHASE3 domain SAM_PNT PF02198.16 ORY44460.1 - 0.035 14.1 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF4240 PF14024.6 ORY44460.1 - 0.058 13.6 0.8 0.26 11.5 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4240) AAA_16 PF13191.6 ORY44460.1 - 0.065 13.6 0.3 0.27 11.6 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain DEAD PF00270.29 ORY44460.1 - 0.17 11.7 0.5 0.32 10.8 0.5 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase STI1 PF17830.1 ORY44460.1 - 0.17 11.9 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 STI1 domain Peptidase_M13_N PF05649.13 ORY44461.1 - 5.6e-73 246.8 1.7 7.7e-73 246.4 1.7 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 ORY44461.1 - 8.1e-68 228.1 0.0 1.4e-67 227.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M13 PfkB PF00294.24 ORY44462.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Bromodomain PF00439.25 ORY44464.1 - 1.5e-11 44.2 0.1 2.9e-11 43.3 0.1 1.5 1 1 0 1 1 1 1 Bromodomain BET PF17035.5 ORY44465.1 - 2.5e-16 59.6 0.6 5.2e-16 58.6 0.6 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation GATA PF00320.27 ORY44465.1 - 1.3e-11 43.9 6.0 2.1e-11 43.2 6.0 1.4 1 0 0 1 1 1 1 GATA zinc finger IQ_SEC7_PH PF16453.5 ORY44465.1 - 0.01 15.8 0.5 0.022 14.8 0.5 1.4 1 0 0 1 1 1 0 PH domain IMUP PF15761.5 ORY44465.1 - 0.041 14.6 11.1 0.041 14.6 11.1 2.9 3 0 0 3 3 3 0 Immortalisation up-regulated protein DUF2956 PF11169.8 ORY44465.1 - 0.076 13.2 0.4 0.076 13.2 0.4 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2956) Cwf_Cwc_15 PF04889.12 ORY44465.1 - 0.31 10.8 13.8 0.031 14.0 4.7 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 ORY44465.1 - 0.53 10.1 9.3 0.26 11.1 0.9 2.4 2 1 0 2 2 2 0 Sigma-70, non-essential region SURF2 PF05477.11 ORY44465.1 - 1.7 8.3 10.1 0.19 11.4 4.0 2.0 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) DUF1117 PF06547.12 ORY44465.1 - 2.3 8.8 6.8 2.3 8.8 3.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1117) AF-4 PF05110.13 ORY44465.1 - 3 5.8 30.6 6.3 4.8 30.6 1.6 1 1 0 1 1 1 0 AF-4 proto-oncoprotein TP_methylase PF00590.20 ORY44466.1 - 4.8e-28 98.6 1.2 8.6e-28 97.7 0.1 2.0 2 1 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases BTB PF00651.31 ORY44468.1 - 1e-16 61.2 0.0 6.4e-12 45.7 0.0 2.6 1 1 1 2 2 2 2 BTB/POZ domain BACK PF07707.15 ORY44468.1 - 0.0055 16.8 0.3 0.074 13.2 0.0 2.4 2 0 0 2 2 2 1 BTB And C-terminal Kelch GLTP PF08718.11 ORY44468.1 - 0.067 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) RCC1 PF00415.18 ORY44469.1 - 1.3e-32 112.2 6.8 1.1e-09 38.8 0.0 5.5 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY44469.1 - 3e-12 46.0 14.5 3e-06 26.9 0.1 6.6 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat Ank_5 PF13857.6 ORY44469.1 - 3.6e-05 23.9 0.1 0.00017 21.8 0.1 2.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) BTB PF00651.31 ORY44469.1 - 0.0036 17.5 0.0 0.0086 16.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF1459 PF07312.11 ORY44469.1 - 0.9 9.8 4.9 9.2 6.6 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1459) Bax1-I PF01027.20 ORY44470.1 - 1.1e-18 67.9 3.4 1.5e-18 67.4 3.4 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 SET PF00856.28 ORY44471.1 - 3.9e-12 46.9 0.2 1.3e-11 45.1 0.2 2.0 1 1 0 1 1 1 1 SET domain TPR_2 PF07719.17 ORY44471.1 - 0.00088 19.2 0.7 0.12 12.6 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY44471.1 - 0.0023 18.2 0.9 2 8.8 0.5 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF3856 PF12968.7 ORY44471.1 - 0.024 14.7 0.2 0.063 13.4 0.2 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) PI3_PI4_kinase PF00454.27 ORY44473.1 - 4.7e-54 183.8 0.0 1.1e-53 182.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 ORY44473.1 - 1e-12 47.6 0.3 3.6e-12 45.9 0.1 2.1 2 0 0 2 2 2 1 FATC domain Hit1_C PF18268.1 ORY44473.1 - 0.054 13.6 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 Hit1 C-terminal Mce4_CUP1 PF11887.8 ORY44473.1 - 0.06 12.8 0.8 0.82 9.1 0.0 2.2 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative DUF4042 PF13251.6 ORY44474.1 - 0.0012 18.5 0.5 0.035 13.8 0.0 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF4042) TAN PF11640.8 ORY44475.1 - 9.9e-06 25.8 3.8 0.0032 17.6 0.1 4.3 5 0 0 5 5 5 1 Telomere-length maintenance and DNA damage repair WbqC PF08889.11 ORY44475.1 - 0.0045 16.9 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 WbqC-like protein family RPAP1_C PF08620.10 ORY44475.1 - 0.059 13.5 1.0 0.19 11.9 0.3 2.2 2 0 0 2 2 2 0 RPAP1-like, C-terminal UME PF08064.13 ORY44475.1 - 0.11 12.4 1.9 0.63 10.0 0.3 2.7 2 0 0 2 2 2 0 UME (NUC010) domain AKAP2_C PF15304.6 ORY44475.1 - 0.12 11.7 2.0 0.2 10.9 2.0 1.2 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus CDC45 PF02724.14 ORY44476.1 - 1.4 7.1 5.3 2 6.6 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein ATP-grasp_3 PF02655.14 ORY44477.1 - 0.19 11.8 0.0 4.6 7.3 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain UQ_con PF00179.26 ORY44478.1 - 1.7e-34 118.5 0.0 2.1e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY44478.1 - 0.063 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B peroxidase PF00141.23 ORY44479.1 - 3e-12 46.7 0.0 4.3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase Actin PF00022.19 ORY44480.1 - 6.1e-86 288.6 0.0 1.4e-83 280.8 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 ORY44480.1 - 0.0082 15.0 0.0 1.8 7.3 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein baeRF_family10 PF18854.1 ORY44480.1 - 0.072 13.3 0.0 0.3 11.3 0.0 1.9 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 GCOM2 PF15328.6 ORY44481.1 - 5.9e-08 33.4 1.8 9.4e-08 32.7 1.7 1.5 1 1 0 1 1 1 1 Putative GRINL1B complex locus protein 2 RICTOR_phospho PF14665.6 ORY44481.1 - 0.085 13.2 0.1 0.52 10.7 0.0 2.2 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site Cupin_2 PF07883.11 ORY44482.1 - 6.3e-12 45.0 1.3 3.5e-05 23.4 0.0 2.7 3 0 0 3 3 3 2 Cupin domain Cupin_3 PF05899.12 ORY44482.1 - 1.2e-06 28.1 0.1 0.0049 16.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.7 ORY44482.1 - 3.8e-06 26.8 0.0 0.0046 16.7 0.0 2.4 2 0 0 2 2 2 2 Cupin HutD PF05962.11 ORY44482.1 - 0.0007 19.6 0.0 0.0034 17.4 0.0 2.0 3 0 0 3 3 3 1 HutD Ectoine_synth PF06339.12 ORY44482.1 - 0.0079 16.4 0.1 0.33 11.1 0.0 2.1 2 0 0 2 2 2 1 Ectoine synthase Ppnp PF06865.11 ORY44482.1 - 0.0096 16.3 0.0 0.022 15.2 0.0 1.6 1 1 0 1 1 1 1 Pyrimidine/purine nucleoside phosphorylase Pirin_C_2 PF17954.1 ORY44482.1 - 0.18 12.0 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain Ribosomal_S6e PF01092.19 ORY44483.1 - 4.3e-57 191.5 0.1 7.5e-57 190.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e HEAT_2 PF13646.6 ORY44484.1 - 0.00066 20.0 0.2 0.0044 17.4 0.1 2.4 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 ORY44484.1 - 0.0029 17.7 1.8 0.05 13.9 0.1 3.6 3 0 0 3 3 3 1 HEAT repeat SUZ PF12752.7 ORY44484.1 - 0.1 13.4 2.5 0.63 10.8 0.1 3.5 2 0 0 2 2 2 0 SUZ domain SIR2 PF02146.17 ORY44486.1 - 4.3e-35 121.2 0.0 5.9e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Mtc PF03820.17 ORY44487.1 - 3.4e-126 420.5 1.1 3.8e-126 420.4 1.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Mannosyl_trans2 PF04188.13 ORY44487.1 - 0.025 13.9 0.6 0.038 13.3 0.6 1.2 1 0 0 1 1 1 0 Mannosyltransferase (PIG-V) SNF2_N PF00176.23 ORY44489.1 - 5.1e-60 203.0 0.0 5.1e-60 203.0 0.0 2.8 2 1 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY44489.1 - 6.9e-17 61.8 0.0 6.9e-17 61.8 0.0 3.4 5 0 0 5 5 5 1 Helicase conserved C-terminal domain Hamartin PF04388.12 ORY44489.1 - 0.092 11.4 23.1 0.15 10.7 23.1 1.3 1 0 0 1 1 1 0 Hamartin protein SID-1_RNA_chan PF13965.6 ORY44489.1 - 1.9 6.8 8.5 3.1 6.1 8.5 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CLN3 PF02487.17 ORY44489.1 - 3.9 6.4 15.3 6.9 5.6 15.3 1.4 1 0 0 1 1 1 0 CLN3 protein Ribosomal_60s PF00428.19 ORY44489.1 - 6.1 7.5 20.5 0.064 13.8 1.8 4.3 4 0 0 4 4 4 0 60s Acidic ribosomal protein Folate_carrier PF01770.18 ORY44489.1 - 8.4 5.0 10.2 14 4.2 10.2 1.3 1 0 0 1 1 1 0 Reduced folate carrier ALMT PF11744.8 ORY44489.1 - 8.7 5.1 15.1 23 3.7 15.1 1.7 1 0 0 1 1 1 0 Aluminium activated malate transporter TFIIA PF03153.13 ORY44490.1 - 0.048 13.7 10.0 0.054 13.5 10.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SBP_bac_3 PF00497.20 ORY44490.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 Peptidase_M24 PF00557.24 ORY44491.1 - 2.9e-22 79.4 0.4 4.1e-22 78.9 0.4 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 tRNA-synt_2 PF00152.20 ORY44492.1 - 1.1e-80 271.0 0.0 1.5e-80 270.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORY44492.1 - 5.1e-07 29.6 0.3 9e-07 28.8 0.3 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ORY44492.1 - 0.14 11.6 0.0 0.56 9.6 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Trimer_CC PF08954.11 ORY44492.1 - 0.45 10.1 1.6 0.87 9.2 1.6 1.4 1 0 0 1 1 1 0 Trimerisation motif AhpC-TSA PF00578.21 ORY44493.1 - 4.2e-37 126.8 0.0 5.4e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY44493.1 - 3.5e-15 56.0 0.0 4.5e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 ORY44493.1 - 2.5e-09 36.8 0.0 4.4e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin 2-Hacid_dh_C PF02826.19 ORY44494.1 - 9.9e-54 181.4 0.0 1.3e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY44494.1 - 1.6e-22 79.6 0.0 1.8e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.17 ORY44494.1 - 0.00031 21.3 0.0 0.00067 20.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 ORY44494.1 - 0.0011 19.2 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 ORY44494.1 - 0.03 14.4 0.3 0.14 12.3 0.0 2.0 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.18 ORY44494.1 - 0.047 13.9 0.1 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain peroxidase PF00141.23 ORY44495.1 - 1e-33 117.0 0.1 1.7e-33 116.3 0.1 1.3 1 0 0 1 1 1 1 Peroxidase Vint PF14623.6 ORY44496.1 - 3.6e-27 95.2 0.0 6.2e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.6 ORY44496.1 - 2.7e-24 85.1 0.0 6.1e-24 83.9 0.0 1.6 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_2 PF13519.6 ORY44496.1 - 2e-14 54.1 0.3 4.2e-14 53.1 0.3 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 ORY44496.1 - 1.3e-13 51.6 0.0 2.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 ORY44496.1 - 2.2e-09 37.4 0.0 1.2e-08 35.0 0.0 2.3 2 1 0 2 2 2 1 von Willebrand factor type A domain Hint PF01079.20 ORY44496.1 - 1.9e-05 24.3 0.0 3.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Hint module VWA_CoxE PF05762.14 ORY44496.1 - 0.12 11.7 0.3 1.2 8.5 0.1 2.2 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein DUF4100 PF13352.6 ORY44497.1 - 0.042 13.6 1.5 0.091 12.5 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) DUF4407 PF14362.6 ORY44497.1 - 1.4 8.2 4.8 2.6 7.3 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ndc1_Nup PF09531.10 ORY44497.1 - 7 5.2 5.7 11 4.5 5.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Gly_transf_sug PF04488.15 ORY44498.1 - 3.8e-09 37.0 0.0 1.3e-08 35.3 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Glycos_transf_2 PF00535.26 ORY44498.1 - 1.2e-08 35.0 0.0 2.9e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 fn3 PF00041.21 ORY44498.1 - 0.00094 19.5 1.2 0.017 15.5 0.3 3.3 2 1 0 2 2 2 1 Fibronectin type III domain Glyco_tranf_2_3 PF13641.6 ORY44498.1 - 0.0067 16.3 0.3 0.027 14.3 0.3 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Usp PF00582.26 ORY44499.1 - 1.8e-21 77.2 0.1 6e-21 75.4 0.1 1.7 1 1 0 1 1 1 1 Universal stress protein family Cofac_haem_bdg PF04187.13 ORY44499.1 - 0.14 12.1 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN Usp PF00582.26 ORY44500.1 - 5.3e-21 75.6 1.5 8.8e-21 74.9 1.5 1.4 1 1 0 1 1 1 1 Universal stress protein family STE3 PF02076.15 ORY44502.1 - 0.048 12.9 0.0 0.055 12.7 0.0 1.1 1 0 0 1 1 1 0 Pheromone A receptor Vault_3 PF17795.1 ORY44502.1 - 0.13 12.4 0.0 0.71 10.0 0.0 2.1 2 0 0 2 2 2 0 Major Vault Protein Repeat domain PPV_E2_C PF00511.17 ORY44503.1 - 0.099 12.8 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 E2 (early) protein, C terminal Usp PF00582.26 ORY44504.1 - 6e-10 39.8 0.4 3.9e-09 37.1 0.4 1.9 1 1 0 1 1 1 1 Universal stress protein family SNAD1 PF18744.1 ORY44505.1 - 0.042 13.7 0.1 0.06 13.2 0.1 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 1 DUF2688 PF10892.8 ORY44505.1 - 0.11 12.0 0.0 19 4.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2688) Usp PF00582.26 ORY44506.1 - 0.0029 18.1 0.0 0.0042 17.6 0.0 1.6 1 1 0 1 1 1 1 Universal stress protein family ABC2_membrane_2 PF12679.7 ORY44508.1 - 0.018 14.3 0.6 0.031 13.6 0.6 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Jiraiya PF15038.6 ORY44508.1 - 0.026 13.9 1.7 0.06 12.8 1.7 1.5 1 0 0 1 1 1 0 Jiraiya DEAD PF00270.29 ORY44509.1 - 6.4e-46 156.3 0.0 3.7e-45 153.8 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY44509.1 - 1.6e-30 105.7 0.0 6.2e-30 103.8 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY44509.1 - 0.00018 21.5 0.0 0.0013 18.8 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 ORY44509.1 - 0.067 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain zf-CCHC_2 PF13696.6 ORY44509.1 - 0.085 12.7 2.0 0.2 11.5 2.0 1.7 1 0 0 1 1 1 0 Zinc knuckle LBP_BPI_CETP_C PF02886.17 ORY44509.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 LBP / BPI / CETP family, C-terminal domain zf-CCHC PF00098.23 ORY44509.1 - 0.16 12.1 1.5 0.26 11.4 1.5 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 ORY44509.1 - 0.37 10.6 1.2 0.91 9.3 1.2 1.7 1 0 0 1 1 1 0 Zinc knuckle LRR_8 PF13855.6 ORY44510.1 - 6.7e-21 73.8 26.1 1.3e-06 28.0 1.8 5.9 4 1 1 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 ORY44510.1 - 1.8e-12 47.3 36.5 0.00055 20.3 2.7 7.1 4 2 5 9 9 9 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY44510.1 - 7.1e-06 25.9 38.3 0.73 10.6 0.1 10.6 11 0 0 11 11 11 5 Leucine Rich Repeat LRR_6 PF13516.6 ORY44510.1 - 0.038 14.1 32.0 0.1 12.7 0.1 8.2 8 0 0 8 8 8 0 Leucine Rich repeat MCM_N PF14551.6 ORY44510.1 - 0.055 14.1 0.5 0.41 11.3 0.1 2.2 2 0 0 2 2 2 0 MCM N-terminal domain CCDC24 PF15669.5 ORY44510.1 - 0.34 10.8 2.9 0.39 10.6 0.2 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Synaptobrevin PF00957.21 ORY44511.1 - 1.2e-21 76.3 0.6 1.4e-21 76.0 0.6 1.1 1 0 0 1 1 1 1 Synaptobrevin Fzo_mitofusin PF04799.13 ORY44511.1 - 0.043 13.4 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF4566 PF15130.6 ORY44511.1 - 0.058 12.8 0.1 0.066 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) 7tm_3 PF00003.22 ORY44513.1 - 1.9e-16 60.5 21.0 3.9e-16 59.5 21.0 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 ORY44513.1 - 1.2e-09 37.8 1.0 0.0015 17.7 0.6 3.8 1 1 2 3 3 3 2 Receptor family ligand binding region P5-ATPase PF12409.8 ORY44513.1 - 0.28 11.3 3.8 13 5.9 0.3 3.4 3 0 0 3 3 3 0 P5-type ATPase cation transporter ANF_receptor PF01094.28 ORY44514.1 - 1.7e-12 47.2 0.2 2.7e-12 46.5 0.2 1.3 1 1 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY44514.1 - 0.0065 16.2 0.0 0.013 15.2 0.0 1.6 1 1 0 1 1 1 1 Periplasmic binding protein DUF1533 PF07550.11 ORY44514.1 - 0.027 14.3 1.0 0.16 11.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1533) 7tm_3 PF00003.22 ORY44515.1 - 2.1e-20 73.5 15.0 3.8e-20 72.6 15.0 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Tmemb_14 PF03647.13 ORY44515.1 - 0.027 15.2 1.1 0.027 15.2 1.1 2.4 2 1 0 2 2 2 0 Transmembrane proteins 14C DUF2157 PF09925.9 ORY44515.1 - 8.2 6.2 7.6 1.6e+02 2.1 7.6 2.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) PXA PF02194.15 ORY44516.1 - 3.3e-28 98.9 0.8 2e-27 96.3 0.1 2.5 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 ORY44516.1 - 2.5e-22 79.5 0.2 6.9e-22 78.1 0.2 1.8 1 0 0 1 1 1 1 Sorting nexin C terminal C2 PF00168.30 ORY44516.1 - 7.3e-14 51.9 0.0 1.5e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain Npa1 PF11707.8 ORY44516.1 - 0.073 12.4 0.0 2.6 7.3 0.0 2.5 2 0 0 2 2 2 0 Ribosome 60S biogenesis N-terminal PRKCSH-like PF12999.7 ORY44517.1 - 6.9e-46 156.2 3.5 6.9e-46 156.2 3.5 2.3 3 0 0 3 3 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 ORY44517.1 - 4.1e-31 107.8 1.7 4.5e-31 107.6 0.2 1.9 2 0 0 2 2 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 ORY44517.1 - 2.2e-08 35.0 0.6 6e-08 33.6 0.6 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein DUF2408 PF10303.9 ORY44517.1 - 5.3e-06 27.0 11.4 4.6e-05 24.0 8.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2408) Prefoldin_2 PF01920.20 ORY44517.1 - 0.00015 21.7 3.6 0.00015 21.7 3.6 2.6 3 0 0 3 3 2 1 Prefoldin subunit Mus7 PF09462.10 ORY44517.1 - 0.1 11.4 1.9 0.14 11.0 1.9 1.1 1 0 0 1 1 1 0 Mus7/MMS22 family Baculo_PEP_C PF04513.12 ORY44517.1 - 0.12 12.4 4.4 0.27 11.3 4.4 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dam1 PF08653.10 ORY44517.1 - 0.13 12.1 1.1 1.3 8.9 0.2 2.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 DNA_topoisoIV PF00521.20 ORY44517.1 - 0.23 10.3 6.2 0.38 9.6 6.2 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF2730 PF10805.8 ORY44517.1 - 0.39 10.8 6.3 9.4 6.4 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) DUF4349 PF14257.6 ORY44517.1 - 0.89 9.0 4.8 1.7 8.0 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) MRP-S26 PF14943.6 ORY44517.1 - 1.2 9.1 16.4 0.21 11.5 0.4 2.8 2 1 0 2 2 2 0 Mitochondrial ribosome subunit S26 PspB PF06667.12 ORY44517.1 - 1.3 9.1 3.4 15 5.7 0.3 2.9 3 0 0 3 3 3 0 Phage shock protein B DUF5082 PF16888.5 ORY44517.1 - 1.6 9.0 14.1 12 6.2 3.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) DMPK_coil PF08826.10 ORY44517.1 - 3 8.0 20.1 0.61 10.2 4.1 3.5 3 0 0 3 3 3 0 DMPK coiled coil domain like Mod_r PF07200.13 ORY44517.1 - 3.4 7.8 18.2 2.3 8.3 11.5 2.7 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Cluap1 PF10234.9 ORY44517.1 - 3.9 6.8 16.1 0.065 12.6 8.3 1.7 2 0 0 2 2 2 0 Clusterin-associated protein-1 Exonuc_VII_L PF02601.15 ORY44517.1 - 4.3 6.8 11.4 0.22 11.0 5.8 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF3450 PF11932.8 ORY44517.1 - 4.4 6.5 15.7 0.2 10.9 8.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Prefoldin PF02996.17 ORY44517.1 - 5 7.1 14.9 0.11 12.4 0.5 2.9 2 1 1 3 3 2 0 Prefoldin subunit MerR-DNA-bind PF09278.11 ORY44517.1 - 5.9 7.5 11.5 17 6.1 2.1 3.4 3 0 0 3 3 3 0 MerR, DNA binding TPR_MLP1_2 PF07926.12 ORY44517.1 - 6.6 6.8 26.7 0.15 12.1 15.0 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Fzo_mitofusin PF04799.13 ORY44517.1 - 9.1 5.8 13.6 3.3 7.2 0.8 2.8 2 1 1 3 3 3 0 fzo-like conserved region Fib_alpha PF08702.10 ORY44517.1 - 9.1 6.5 16.1 0.62 10.2 5.9 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family LMBR1 PF04791.16 ORY44517.1 - 9.7 5.0 6.2 13 4.6 0.1 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF3097 PF11296.8 ORY44518.1 - 0.11 11.7 0.0 0.11 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3097) PPR_2 PF13041.6 ORY44519.1 - 1.3e-47 159.7 1.3 1.2e-09 38.1 0.0 8.0 6 2 3 9 9 9 9 PPR repeat family PPR PF01535.20 ORY44519.1 - 5.8e-40 132.8 5.9 5.6e-05 23.1 0.0 9.4 10 0 0 10 10 10 8 PPR repeat PPR_1 PF12854.7 ORY44519.1 - 5.8e-34 115.5 0.0 3.5e-05 23.4 0.0 9.9 10 0 0 10 10 10 8 PPR repeat PPR_3 PF13812.6 ORY44519.1 - 3.3e-31 107.2 0.0 1.9e-06 27.9 0.1 7.2 6 1 1 7 7 7 7 Pentatricopeptide repeat domain PPR_long PF17177.4 ORY44519.1 - 8.2e-18 64.5 0.3 4.8e-08 32.6 0.8 4.3 2 2 1 4 4 4 4 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 ORY44519.1 - 4.4e-07 29.7 0.1 1.4 8.7 0.0 5.4 2 1 4 6 6 6 2 Mitochondrial ATPase expression RPM2 PF08579.11 ORY44519.1 - 0.005 17.2 0.0 8.9 6.8 0.0 3.2 2 1 1 3 3 3 2 Mitochondrial ribonuclease P subunit (RPM2) TPR_MalT PF17874.1 ORY44519.1 - 0.025 14.0 0.0 0.18 11.1 0.0 2.1 2 1 0 2 2 2 0 MalT-like TPR region SPO22 PF08631.10 ORY44519.1 - 0.026 14.0 0.1 0.3 10.5 0.0 2.4 3 0 0 3 3 3 0 Meiosis protein SPO22/ZIP4 like TPR_2 PF07719.17 ORY44519.1 - 0.037 14.1 1.5 2.7 8.3 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Clathrin PF00637.20 ORY44519.1 - 0.037 13.9 0.3 0.79 9.6 0.7 3.0 3 1 2 5 5 5 0 Region in Clathrin and VPS MRP-S27 PF10037.9 ORY44519.1 - 0.13 11.1 0.2 9.5 5.0 0.1 2.9 2 1 1 3 3 3 0 Mitochondrial 28S ribosomal protein S27 Glyco_hydro_19 PF00182.19 ORY44521.1 - 6.9e-13 49.0 1.1 2.3e-12 47.3 0.5 1.9 1 1 1 2 2 2 1 Chitinase class I Glyco_hydro_19 PF00182.19 ORY44522.1 - 4.4e-11 43.1 1.0 5.1e-11 42.9 0.1 1.6 2 0 0 2 2 2 1 Chitinase class I VSP PF03302.13 ORY44522.1 - 0.00053 19.0 1.1 0.00053 19.0 1.1 2.1 2 0 0 2 2 2 1 Giardia variant-specific surface protein CD99L2 PF12301.8 ORY44522.1 - 0.00074 19.9 1.2 0.0016 18.8 1.2 1.5 1 0 0 1 1 1 1 CD99 antigen like protein 2 ABC_tran PF00005.27 ORY44524.1 - 9.9e-33 113.6 0.0 1.6e-18 67.6 0.0 2.7 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ORY44524.1 - 4.8e-11 43.0 3.5 0.00027 20.8 0.1 4.1 2 2 2 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY44524.1 - 3.1e-08 33.2 1.0 0.0055 16.4 0.1 2.8 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_18 PF13238.6 ORY44524.1 - 1.4e-05 25.7 0.1 0.2 12.2 0.0 3.2 4 0 0 4 4 3 2 AAA domain SMC_N PF02463.19 ORY44524.1 - 4.1e-05 23.1 3.6 5 6.5 0.0 4.2 4 0 0 4 4 4 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY44524.1 - 0.00033 20.7 0.2 0.24 11.5 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_25 PF13481.6 ORY44524.1 - 0.00055 19.6 0.1 9.3 5.8 0.1 3.8 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.6 ORY44524.1 - 0.0017 18.6 0.1 0.74 10.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 ORY44524.1 - 0.0022 17.6 0.7 0.43 10.2 0.1 3.2 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 ORY44524.1 - 0.0027 18.0 0.0 2.8 8.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 ORY44524.1 - 0.0042 17.0 0.1 1.2 9.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_7 PF12775.7 ORY44524.1 - 0.0045 16.5 0.0 0.49 9.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region dNK PF01712.19 ORY44524.1 - 0.0064 16.4 0.0 0.28 11.0 0.0 2.3 2 0 0 2 2 2 1 Deoxynucleoside kinase Acyl-CoA_dh_M PF02770.19 ORY44524.1 - 0.0085 16.3 0.0 0.023 14.9 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AAA_33 PF13671.6 ORY44524.1 - 0.015 15.5 2.6 3.9 7.6 0.1 2.8 3 0 0 3 3 2 0 AAA domain RsgA_GTPase PF03193.16 ORY44524.1 - 0.018 14.9 0.3 7.7 6.4 0.1 2.5 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 ORY44524.1 - 0.032 14.7 7.4 0.51 10.8 1.0 2.7 2 2 0 2 2 2 0 AAA domain Ploopntkinase1 PF18748.1 ORY44524.1 - 0.042 13.4 0.0 0.5 9.9 0.0 2.5 3 0 0 3 3 3 0 P-loop Nucleotide Kinase1 AAA_24 PF13479.6 ORY44524.1 - 0.044 13.5 0.2 4.3 7.0 0.1 2.7 3 0 0 3 3 3 0 AAA domain MeaB PF03308.16 ORY44524.1 - 0.047 12.7 0.1 0.67 8.9 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 ORY44524.1 - 0.064 13.2 3.1 6.1 6.7 0.1 3.2 3 0 0 3 3 3 0 NTPase T2SSE PF00437.20 ORY44524.1 - 0.065 12.3 0.1 0.89 8.6 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_16 PF13191.6 ORY44524.1 - 0.09 13.2 0.1 20 5.5 0.1 2.9 3 0 0 3 3 3 0 AAA ATPase domain TsaE PF02367.17 ORY44524.1 - 0.093 12.7 0.1 12 5.9 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 ORY44524.1 - 0.1 12.3 0.1 5.1 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 ORY44524.1 - 0.16 12.0 0.6 7.2 6.6 0.1 2.8 2 1 0 2 2 2 0 Dynamin family NB-ARC PF00931.22 ORY44524.1 - 0.51 9.5 2.2 11 5.1 0.1 2.8 3 0 0 3 3 3 0 NB-ARC domain CoaE PF01121.20 ORY44524.1 - 0.93 9.1 2.6 39 3.9 0.1 3.2 4 0 0 4 4 4 0 Dephospho-CoA kinase IQ PF00612.27 ORY44525.1 - 0.0028 17.3 0.1 0.0055 16.4 0.1 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif zf-CDGSH PF09360.10 ORY44526.1 - 2.5e-19 69.2 4.8 1.8e-10 40.9 0.3 2.3 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type FF PF01846.19 ORY44527.1 - 1e-32 112.1 4.4 5.9e-11 42.4 0.2 6.1 5 0 0 5 5 5 5 FF domain WW PF00397.26 ORY44527.1 - 2.7e-15 56.1 14.9 4.7e-10 39.4 4.2 3.2 3 0 0 3 3 3 2 WW domain FliS_cochap PF16522.5 ORY44527.1 - 0.014 15.4 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Flagellar FLiS export co-chaperone, HP1076 DUF3014 PF11219.8 ORY44527.1 - 0.1 12.9 0.7 18 5.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3014) Glyco_hyd_101C PF17451.2 ORY44527.1 - 0.39 11.0 4.2 2.4 8.4 0.4 2.9 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain HAD_2 PF13419.6 ORY44527.1 - 0.41 10.7 3.9 4.8 7.2 0.1 3.1 3 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase TetR_C_24 PF17932.1 ORY44527.1 - 0.8 10.0 4.6 0.42 10.9 0.7 2.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Aldedh PF00171.22 ORY44528.1 - 3.5e-75 253.3 0.8 1e-72 245.2 0.8 2.1 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Ras PF00071.22 ORY44528.1 - 0.027 14.1 0.0 0.065 12.8 0.0 1.6 1 0 0 1 1 1 0 Ras family DUF35_N PF12172.8 ORY44528.1 - 0.14 12.1 0.2 0.68 9.9 0.1 2.1 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Prenyltrans PF00432.21 ORY44529.1 - 2.9e-65 215.6 7.5 7.4e-13 48.0 0.1 5.5 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 ORY44529.1 - 8.9e-05 21.7 0.0 0.002 17.3 0.0 2.7 1 1 2 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 ORY44529.1 - 0.0021 17.2 0.0 0.51 9.4 0.0 3.8 1 1 4 5 5 5 3 Squalene-hopene cyclase N-terminal domain zf-MYND PF01753.18 ORY44530.1 - 9.9e-08 32.0 18.4 1.6e-07 31.3 18.4 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY44530.1 - 0.05 13.9 14.9 0.091 13.1 14.9 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding TQ PF18202.1 ORY44530.1 - 0.14 12.7 0.1 0.23 12.0 0.1 1.3 1 0 0 1 1 1 0 T-Q ester bond containing domain MFS_1 PF07690.16 ORY44531.1 - 1.8e-09 37.0 21.8 2.7e-09 36.4 21.8 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY44531.1 - 0.00039 19.4 3.9 0.00039 19.4 3.9 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter Choline_transpo PF04515.12 ORY44532.1 - 8.4e-16 58.1 31.0 6.9e-14 51.8 2.1 4.6 3 1 1 5 5 5 3 Plasma-membrane choline transporter DDE_3 PF13358.6 ORY44533.1 - 0.007 16.1 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease ADP_ribosyl_GH PF03747.14 ORY44535.1 - 1e-39 137.1 7.1 1e-39 137.1 7.1 1.8 2 0 0 2 2 2 1 ADP-ribosylglycohydrolase MFS_1 PF07690.16 ORY44536.1 - 1.1e-20 73.8 64.9 5.3e-13 48.6 13.5 3.4 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 ORY44536.1 - 0.24 9.6 14.4 0.68 8.2 0.1 3.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family YlaC PF10777.9 ORY44536.1 - 2 8.2 4.8 0.69 9.8 0.7 2.2 2 0 0 2 2 2 0 Inner membrane protein YlaC SH3_1 PF00018.28 ORY44537.1 - 2.4e-38 129.5 8.7 1.3e-15 56.7 0.2 3.7 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 ORY44537.1 - 9.9e-34 115.0 9.2 6.3e-12 45.2 0.5 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 ORY44537.1 - 2.6e-20 71.9 0.0 2.2e-06 27.3 0.0 3.9 4 0 0 4 4 4 3 Variant SH3 domain SHD1 PF03983.12 ORY44537.1 - 7.9e-10 38.4 0.2 2.5e-07 30.4 0.3 2.5 1 1 1 2 2 2 2 SLA1 homology domain 1, SHD1 SH3_10 PF17902.1 ORY44537.1 - 1.6e-07 31.3 0.0 0.021 14.9 0.0 3.6 3 0 0 3 3 3 2 SH3 domain SAM_4 PF18017.1 ORY44537.1 - 7.1e-06 25.9 0.0 2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ank_5 PF13857.6 ORY44538.1 - 2.4e-14 53.2 6.9 0.00079 19.7 0.1 8.1 9 0 0 9 9 9 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY44538.1 - 6.2e-08 33.0 14.3 0.0042 17.6 0.0 8.1 10 1 0 10 10 10 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY44538.1 - 3.1e-05 24.5 15.5 0.0006 20.4 0.3 7.6 7 3 1 8 8 8 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY44538.1 - 0.024 15.1 4.9 15 6.6 0.0 6.4 8 0 0 8 8 8 0 Ankyrin repeat Mto2_bdg PF12808.7 ORY44539.1 - 0.044 14.1 0.9 0.044 14.1 0.9 5.2 5 3 1 6 6 6 0 Micro-tubular organiser Mto1 C-term Mto2-binding region MLD PF11647.8 ORY44539.1 - 0.43 10.9 6.5 3.5 8.0 0.2 3.6 2 1 1 3 3 3 0 Membrane Localization Domain LRRFIP PF09738.9 ORY44539.1 - 3.7 6.9 43.1 0.12 11.8 11.4 3.1 3 0 0 3 3 3 0 LRRFIP family Band_7 PF01145.25 ORY44540.1 - 1.1e-28 100.4 1.1 1.5e-28 100.0 1.1 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family zf-CCHC PF00098.23 ORY44541.1 - 8.6e-07 28.8 1.9 1.7e-06 27.8 1.9 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF1510 PF07423.11 ORY44541.1 - 0.01 16.0 0.1 0.025 14.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1510) gp32 PF08804.10 ORY44541.1 - 0.061 13.4 0.3 0.089 12.8 0.3 1.3 1 0 0 1 1 1 0 gp32 DNA binding protein like Pkinase PF00069.25 ORY44544.1 - 3.3e-23 82.4 0.0 6.4e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY44544.1 - 3.2e-10 39.7 0.1 6.8e-10 38.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY44544.1 - 1.1e-07 31.0 0.8 4.9e-07 28.9 0.0 2.3 2 1 0 2 2 2 1 Fungal protein kinase ABC_tran PF00005.27 ORY44545.1 - 6e-44 149.9 0.0 7.9e-23 81.5 0.0 3.5 3 0 0 3 3 3 3 ABC transporter ABC_tran_Xtn PF12848.7 ORY44545.1 - 1.2e-21 76.5 3.0 1.2e-21 76.5 3.0 2.3 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.6 ORY44545.1 - 1.2e-09 38.5 7.5 0.00076 19.4 0.0 4.1 2 2 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY44545.1 - 2.3e-06 27.2 1.8 0.3 10.5 0.0 4.1 3 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 ORY44545.1 - 0.00053 20.3 0.1 1.5 9.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ORY44545.1 - 0.00061 19.7 1.0 0.005 16.8 0.0 2.6 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 ORY44545.1 - 0.0011 19.3 0.4 0.027 14.9 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.23 ORY44545.1 - 0.0018 18.3 0.0 0.043 13.9 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY44545.1 - 0.0026 17.5 1.4 0.0085 15.8 0.0 2.4 3 0 0 3 3 2 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 ORY44545.1 - 0.0044 17.4 0.6 0.43 11.0 0.0 3.3 3 0 0 3 3 3 1 RNA helicase AAA_23 PF13476.6 ORY44545.1 - 0.0057 17.2 7.0 0.06 13.8 0.0 3.3 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 ORY44545.1 - 0.0063 17.1 0.0 0.68 10.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 ORY44545.1 - 0.0065 16.5 0.0 7.5 6.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 ORY44545.1 - 0.007 16.3 0.6 0.027 14.4 0.1 2.2 2 0 0 2 2 2 1 NACHT domain Dynamin_N PF00350.23 ORY44545.1 - 0.007 16.4 0.4 1.5 8.9 0.0 3.2 3 1 1 4 4 4 1 Dynamin family AAA_33 PF13671.6 ORY44545.1 - 0.025 14.7 0.0 1.4 9.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ORY44545.1 - 0.029 14.6 0.0 0.22 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ORY44545.1 - 0.045 14.2 0.1 2.6 8.5 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 ORY44545.1 - 0.059 13.1 0.0 0.21 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain DUF87 PF01935.17 ORY44545.1 - 0.075 13.1 1.0 0.42 10.7 0.0 2.5 2 1 0 2 2 2 0 Helicase HerA, central domain Arf PF00025.21 ORY44545.1 - 0.11 11.9 0.0 0.31 10.5 0.0 1.7 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_24 PF13479.6 ORY44545.1 - 0.16 11.6 0.7 0.83 9.3 0.0 2.3 3 0 0 3 3 2 0 AAA domain ABC_tran_CTD PF16326.5 ORY44545.1 - 0.33 11.2 9.2 0.051 13.8 2.9 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain TipAS PF07739.13 ORY44545.1 - 0.41 11.2 4.2 13 6.4 0.1 2.8 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain CAMSAP_CKK PF08683.11 ORY44546.1 - 2.6e-28 98.6 0.1 1.6e-19 70.2 0.0 2.5 2 0 0 2 2 2 2 Microtubule-binding calmodulin-regulated spectrin-associated CAMSAP_CH PF11971.8 ORY44546.1 - 0.00071 19.4 0.4 1.4 8.8 0.0 4.7 5 0 0 5 5 5 1 CAMSAP CH domain CH_2 PF06294.11 ORY44546.1 - 0.038 14.1 0.1 9.1 6.5 0.0 3.3 2 1 1 3 3 3 0 CH-like domain in sperm protein CH PF00307.31 ORY44546.1 - 0.15 12.2 0.0 2 8.6 0.0 2.6 2 0 0 2 2 2 0 Calponin homology (CH) domain DUF3439 PF11921.8 ORY44547.1 - 0.085 12.8 9.2 0.17 11.8 9.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TatD_DNase PF01026.21 ORY44548.1 - 1.3e-32 113.2 0.0 1.6e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Bin3 PF06859.12 ORY44549.1 - 5.6e-24 84.9 0.0 7.9e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 ORY44549.1 - 1.6e-09 37.7 0.0 6.1e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 ORY44549.1 - 7.3e-09 36.2 0.1 8.3e-05 23.2 0.1 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 ORY44549.1 - 1.3e-06 28.9 0.1 8.4e-05 23.1 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY44549.1 - 1.9e-06 28.5 0.0 3.3e-05 24.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY44549.1 - 2.2e-06 27.6 0.0 2.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY44549.1 - 0.0042 16.7 0.1 0.013 15.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.20 ORY44549.1 - 0.0065 15.8 0.0 2.9 7.1 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase PrmA PF06325.13 ORY44549.1 - 0.0071 15.8 0.1 0.011 15.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 ORY44549.1 - 0.013 14.4 0.0 0.14 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Methyltransf_PK PF05891.12 ORY44549.1 - 0.091 12.3 0.0 0.65 9.5 0.0 1.9 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase PCMT PF01135.19 ORY44549.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) p450 PF00067.22 ORY44551.1 - 5.3e-79 266.1 0.2 7.2e-79 265.7 0.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 LRR_8 PF13855.6 ORY44552.1 - 2.2e-43 145.9 44.7 2.3e-08 33.6 7.0 9.2 5 2 3 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 ORY44552.1 - 1.1e-40 137.0 40.1 6.1e-07 29.7 2.8 11.1 8 1 1 11 11 11 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY44552.1 - 2.7e-17 60.7 56.3 1.8 9.4 0.0 18.3 17 1 1 18 18 18 7 Leucine Rich Repeat LRR_6 PF13516.6 ORY44552.1 - 5.4e-11 41.6 50.3 9.6 6.6 0.0 17.3 18 0 0 18 18 18 3 Leucine Rich repeat F-box PF00646.33 ORY44552.1 - 3.7e-09 36.2 0.0 0.0029 17.4 0.0 3.2 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 ORY44552.1 - 0.00011 22.1 0.7 0.032 14.1 0.1 2.8 2 0 0 2 2 2 2 F-box-like LRR_9 PF14580.6 ORY44552.1 - 0.00074 19.1 11.3 0.16 11.4 0.4 4.5 3 2 1 4 4 4 2 Leucine-rich repeat LRR_4 PF12799.7 ORY44554.1 - 3.1e-14 52.9 0.1 0.00021 21.6 0.0 4.4 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY44554.1 - 1.7e-13 50.1 2.9 6.4e-05 22.6 0.1 5.3 5 1 0 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 ORY44554.1 - 4.9e-09 35.5 3.2 12 6.9 0.0 6.5 6 0 0 6 6 6 3 Leucine Rich Repeat F-box PF00646.33 ORY44554.1 - 3.4e-06 26.8 0.2 8.7e-06 25.5 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY44554.1 - 3.8e-06 26.7 0.6 9.8e-06 25.4 0.6 1.7 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 ORY44554.1 - 0.00011 22.0 5.1 4.8 7.5 0.0 5.2 5 0 0 5 5 5 1 Leucine Rich repeat Adaptin_binding PF10199.9 ORY44555.1 - 1.1e-05 26.0 3.4 1.4e-05 25.7 3.4 1.3 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 LRR_8 PF13855.6 ORY44557.1 - 1.7e-07 30.9 18.5 0.00065 19.4 2.7 3.9 2 1 2 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 ORY44557.1 - 7.4e-05 23.0 21.6 0.071 13.6 1.2 4.3 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY44557.1 - 3 8.7 19.1 6.8 7.7 1.7 5.3 5 3 0 5 5 5 0 Leucine Rich Repeat zf-C3HC4_2 PF13923.6 ORY44558.1 - 2.1e-08 33.9 11.8 2.1e-08 33.9 11.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY44558.1 - 1.3e-06 28.1 11.1 1.3e-06 28.1 11.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY44558.1 - 4.1e-06 27.0 11.8 4.1e-06 27.0 11.8 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORY44558.1 - 2.3e-05 24.1 14.3 2.3e-05 24.1 14.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY44558.1 - 0.0001 22.3 8.9 0.0001 22.3 8.9 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY44558.1 - 0.0032 17.4 14.6 0.0032 17.4 14.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 ORY44558.1 - 0.005 16.7 8.7 0.005 16.7 8.7 2.1 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 ORY44558.1 - 0.029 14.6 6.4 0.029 14.6 6.4 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 ORY44558.1 - 0.047 13.6 20.7 0.058 13.3 14.4 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 ORY44558.1 - 0.54 10.5 21.5 0.067 13.4 13.8 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING p450 PF00067.22 ORY44559.1 - 3.6e-45 154.6 0.2 3.9e-45 154.5 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 RhoGAP PF00620.27 ORY44560.1 - 4e-36 124.1 0.0 1.9e-27 96.0 0.0 2.1 2 0 0 2 2 2 2 RhoGAP domain DUF1708 PF08101.11 ORY44560.1 - 0.11 11.6 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) WW PF00397.26 ORY44561.1 - 5e-06 26.5 1.7 5e-06 26.5 1.7 1.8 2 0 0 2 2 2 1 WW domain PH_9 PF15410.6 ORY44561.1 - 0.074 13.4 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain Homeodomain PF00046.29 ORY44564.1 - 6.1e-05 22.8 0.7 0.00015 21.5 0.7 1.7 1 0 0 1 1 1 1 Homeodomain LRR_8 PF13855.6 ORY44565.1 - 1.7e-16 59.7 45.8 4.7e-07 29.5 5.5 3.6 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 ORY44565.1 - 4.1e-10 39.7 18.0 1.4e-05 25.3 0.6 4.4 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY44565.1 - 9.8e-08 31.5 21.5 1.3 9.8 0.1 7.2 6 0 0 6 6 6 4 Leucine Rich Repeat F-box PF00646.33 ORY44565.1 - 0.078 12.9 0.2 0.17 11.8 0.2 1.6 1 0 0 1 1 1 0 F-box domain Peptidase_C2 PF00648.21 ORY44566.1 - 8.8e-09 34.8 0.0 4.2e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Calpain family cysteine protease Pyr_redox_2 PF07992.14 ORY44567.1 - 3e-41 141.6 0.0 1.3e-40 139.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY44567.1 - 0.00021 21.8 0.1 0.0026 18.3 0.3 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_TMD PF18613.1 ORY44567.1 - 0.083 12.3 1.1 0.2 11.1 1.1 1.6 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain Pyr_redox_3 PF13738.6 ORY44567.1 - 0.12 11.7 0.1 4 6.6 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ArsA_ATPase PF02374.15 ORY44568.1 - 1.8e-110 368.9 0.2 2.1e-110 368.7 0.2 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 ORY44568.1 - 2.6e-12 47.0 0.0 7e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 ORY44568.1 - 1e-10 41.8 0.0 1.7e-10 41.1 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 ORY44568.1 - 7.2e-06 25.6 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 ORY44568.1 - 5.7e-05 22.7 0.7 0.00056 19.4 0.0 2.2 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 ORY44568.1 - 0.00049 19.6 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 ORY44568.1 - 0.0044 16.7 0.1 0.012 15.3 0.0 1.7 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 ORY44568.1 - 0.013 15.2 0.0 0.036 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORY44568.1 - 0.031 13.9 0.1 0.067 12.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ORY44568.1 - 0.066 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Chromo_shadow PF01393.19 ORY44663.1 - 0.023 14.8 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Chromo shadow domain Chromo PF00385.24 ORY44663.1 - 0.046 13.6 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain DUF1796 PF08795.10 ORY44664.1 - 0.75 9.7 2.9 0.67 9.9 0.3 2.2 2 0 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) zf-C2H2 PF00096.26 ORY44665.1 - 0.037 14.5 11.1 9.6 6.9 2.0 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type OrsD PF12013.8 ORY44665.1 - 0.38 11.2 7.4 0.93 10.0 1.8 3.0 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 ORY44665.1 - 2.6 9.1 12.8 23 6.2 2.4 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 ORY44665.1 - 6.3 6.5 8.7 5.5 6.7 1.3 2.5 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain E1-E2_ATPase PF00122.20 ORY44666.1 - 4.4e-28 98.0 1.2 1.1e-27 96.7 1.2 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 ORY44666.1 - 8.4e-17 62.2 1.4 1.9e-16 61.0 1.4 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY44666.1 - 6e-14 51.5 0.0 1.8e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 ORY44666.1 - 3.7e-05 23.7 0.0 0.00012 22.1 0.0 1.9 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY44666.1 - 0.0043 16.8 0.1 0.012 15.4 0.1 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AGTRAP PF06396.11 ORY44666.1 - 0.12 12.2 0.8 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 Angiotensin II, type I receptor-associated protein (AGTRAP) ComJ PF11033.8 ORY44666.1 - 0.17 11.6 0.1 0.39 10.4 0.1 1.5 1 0 0 1 1 1 0 Competence protein J (ComJ) MMR_HSR1_C PF08438.10 ORY44667.1 - 0.056 14.0 0.0 0.085 13.4 0.0 1.3 1 1 0 1 1 1 0 GTPase of unknown function C-terminal YCII PF03795.14 ORY44668.1 - 0.17 12.3 0.0 0.24 11.8 0.0 1.3 1 0 0 1 1 1 0 YCII-related domain ChlI PF13541.6 ORY44669.1 - 0.018 14.9 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Subunit ChlI of Mg-chelatase Ank_2 PF12796.7 ORY44670.1 - 2.1e-27 95.5 0.0 1.8e-11 44.4 0.0 3.9 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY44670.1 - 4.8e-20 71.6 0.3 5.9e-06 26.7 0.0 6.1 5 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY44670.1 - 6.5e-18 63.0 0.0 0.23 12.1 0.0 7.5 7 1 1 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 ORY44670.1 - 4.5e-14 52.3 2.8 0.02 15.2 0.1 7.8 4 1 4 8 8 8 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY44670.1 - 8.4e-10 38.6 0.4 0.32 11.5 0.0 7.3 7 1 1 8 8 8 2 Ankyrin repeat Mur_ligase_M PF08245.12 ORY44671.1 - 0.0018 18.3 2.0 0.33 10.9 0.1 3.4 2 1 1 3 3 3 2 Mur ligase middle domain Mur_ligase_C PF02875.21 ORY44671.1 - 0.078 13.2 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Septin PF00735.18 ORY44672.1 - 5.9e-28 97.9 0.0 1.1e-27 97.1 0.0 1.4 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 ORY44672.1 - 5.8e-06 26.4 0.0 1.3e-05 25.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SH3_9 PF14604.6 ORY44672.1 - 0.00017 21.4 0.0 0.0003 20.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain GTP_EFTU PF00009.27 ORY44672.1 - 0.0033 17.0 0.0 0.025 14.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 ORY44672.1 - 0.0045 17.2 0.0 0.0087 16.3 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SH3_1 PF00018.28 ORY44672.1 - 0.024 14.3 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 SH3 domain Ras PF00071.22 ORY44672.1 - 0.028 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Ras family AAA_16 PF13191.6 ORY44672.1 - 0.04 14.3 0.0 0.064 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 ORY44672.1 - 0.063 13.2 0.1 0.51 10.2 0.1 2.2 2 1 0 2 2 2 0 RsgA GTPase Dynamin_N PF00350.23 ORY44672.1 - 0.1 12.7 0.1 6 6.9 0.0 2.3 1 1 1 2 2 2 0 Dynamin family AAA_24 PF13479.6 ORY44672.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ORY44672.1 - 0.13 12.1 0.0 0.42 10.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain SET PF00856.28 ORY44673.1 - 0.052 13.9 0.0 0.27 11.6 0.0 2.0 1 1 0 1 1 1 0 SET domain Put_Phosphatase PF06888.12 ORY44674.1 - 4.8e-43 147.2 0.0 6.3e-41 140.3 0.0 2.0 1 1 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 ORY44674.1 - 1.5e-05 25.5 0.0 3.2e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Surfac_D-trimer PF09006.11 ORY44674.1 - 0.048 13.6 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation HAD_2 PF13419.6 ORY44674.1 - 0.12 12.5 0.7 0.24 11.5 0.7 1.5 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Coa1 PF08695.10 ORY44674.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 Guanylate_cyc PF00211.20 ORY44675.1 - 1.3e-52 178.1 0.1 1.6e-52 177.8 0.1 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF2521 PF10730.9 ORY44675.1 - 0.036 14.1 0.0 0.069 13.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2521) Guanylate_cyc PF00211.20 ORY44677.1 - 3.5e-52 176.7 0.1 3.5e-52 176.7 0.1 1.7 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain DUF2521 PF10730.9 ORY44677.1 - 0.028 14.4 1.8 0.075 13.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2521) DUF2617 PF10936.8 ORY44677.1 - 0.97 9.5 4.4 2.9 7.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF2617 RapH_N PF18801.1 ORY44677.1 - 3.7 7.7 6.8 0.51 10.5 1.0 2.7 3 0 0 3 3 3 0 response regulator aspartate phosphatase H, N terminal Guanylate_cyc PF00211.20 ORY44678.1 - 2.6e-53 180.4 0.2 5.2e-53 179.4 0.2 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF2521 PF10730.9 ORY44678.1 - 0.029 14.4 0.0 0.029 14.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2521) RNA_pol_Rpb2_6 PF00562.28 ORY44680.1 - 3.4e-93 312.8 0.0 2.4e-47 161.8 0.2 2.2 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 ORY44680.1 - 2.3e-53 180.7 0.1 3.5e-53 180.1 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 ORY44680.1 - 6.6e-30 103.4 0.1 1.6e-29 102.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 ORY44680.1 - 7.9e-25 86.9 0.6 2.1e-24 85.6 0.6 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.14 ORY44680.1 - 4e-22 78.8 0.0 9.1e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 ORY44680.1 - 8e-21 74.0 0.0 1.8e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 ORY44680.1 - 2e-11 44.2 0.4 5.3e-11 42.9 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Ca_chan_IQ PF08763.11 ORY44680.1 - 0.052 13.8 0.0 0.14 12.4 0.0 1.8 1 0 0 1 1 1 0 Voltage gated calcium channel IQ domain Chitin_synth_2 PF03142.15 ORY44681.1 - 4.6e-241 801.0 1.6 2.3e-238 792.1 1.6 2.2 1 1 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORY44681.1 - 7.8e-13 48.8 0.0 2.6e-10 40.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORY44681.1 - 5e-11 42.9 10.2 5e-11 42.9 10.2 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.28 ORY44681.1 - 0.00011 22.3 0.0 0.022 14.9 0.0 2.6 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 ORY44681.1 - 0.002 18.0 1.0 0.047 13.5 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORY44681.1 - 0.014 14.8 0.0 0.11 12.0 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 21 HemY_N PF07219.13 ORY44681.1 - 0.51 10.6 6.3 0.16 12.2 0.4 2.6 2 0 0 2 2 2 0 HemY protein N-terminus Peptidase_M13_N PF05649.13 ORY44682.1 - 1.9e-59 202.3 0.0 2.6e-59 201.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 ORY44682.1 - 2.7e-28 99.0 0.0 4.5e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 DUF1968 PF09291.10 ORY44683.1 - 0.09 12.9 1.1 2.3 8.3 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1968) eIF2A PF08662.11 ORY44684.1 - 1.7e-62 210.8 0.0 1.7e-61 207.5 0.0 2.4 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 ORY44684.1 - 0.73 10.8 3.9 72 4.5 0.0 4.6 4 1 0 4 4 4 0 WD domain, G-beta repeat Mito_carr PF00153.27 ORY44685.1 - 1.6e-21 76.0 2.6 3.9e-09 36.3 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 ORY44687.1 - 8.5e-58 195.8 0.0 3.2e-44 151.3 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY44687.1 - 6.6e-27 94.4 0.0 1e-26 93.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY44687.1 - 4e-09 36.2 0.0 6.4e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY44687.1 - 1.4e-05 24.1 0.0 2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY44687.1 - 2.2e-05 23.6 0.0 2.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 ORY44687.1 - 0.00037 20.2 0.1 0.00057 19.5 0.1 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 ORY44687.1 - 0.0015 18.5 0.0 0.0023 17.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY44687.1 - 0.0023 17.3 0.1 0.0034 16.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3439 PF11921.8 ORY44688.1 - 0.15 12.0 2.5 0.32 11.0 2.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ank_5 PF13857.6 ORY44689.1 - 0.00012 22.3 0.0 0.0055 17.0 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY44689.1 - 0.00031 21.2 0.0 0.012 16.2 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 ORY44689.1 - 0.0004 20.7 0.0 2.1 9.0 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 ORY44689.1 - 0.0012 19.1 0.0 14 6.6 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 ORY44689.1 - 0.014 15.9 0.0 0.59 10.8 0.0 2.0 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) WGR PF05406.15 ORY44690.1 - 0.0012 18.9 0.3 0.0017 18.3 0.3 1.2 1 0 0 1 1 1 1 WGR domain PARP PF00644.20 ORY44691.1 - 5.1e-36 124.1 0.0 7.3e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain DivIC PF04977.15 ORY44692.1 - 0.18 11.6 3.3 0.38 10.6 3.3 1.5 1 0 0 1 1 1 0 Septum formation initiator Pro_isomerase PF00160.21 ORY44693.1 - 1.4e-40 139.1 0.1 1.8e-40 138.8 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Gly_transf_sug PF04488.15 ORY44694.1 - 7.4e-07 29.7 0.0 1.4e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 ORY44694.1 - 0.027 13.9 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein ABC_membrane PF00664.23 ORY44695.1 - 9.5e-77 258.3 17.0 2.4e-56 191.4 10.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY44695.1 - 4.4e-63 211.9 0.0 2.6e-34 118.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY44695.1 - 2.1e-15 56.8 2.8 5.4e-05 22.7 0.1 4.4 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 ORY44695.1 - 3.6e-09 35.9 4.1 0.0008 18.3 0.0 3.1 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 ORY44695.1 - 5.3e-08 33.2 0.0 0.0079 16.5 0.0 3.5 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 ORY44695.1 - 2.3e-07 30.9 0.1 0.028 14.3 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 ORY44695.1 - 1e-06 28.4 2.4 0.012 15.3 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY44695.1 - 2.8e-06 27.8 1.6 0.044 14.2 0.0 3.3 3 1 0 3 3 2 2 AAA ATPase domain AAA_30 PF13604.6 ORY44695.1 - 3.2e-06 27.0 6.3 0.001 18.8 0.0 3.3 4 0 0 4 4 3 2 AAA domain AAA PF00004.29 ORY44695.1 - 1.4e-05 25.5 2.0 4.3 7.8 0.3 4.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 ORY44695.1 - 9.1e-05 22.8 0.3 0.66 10.2 0.0 3.7 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.14 ORY44695.1 - 9.9e-05 22.4 0.1 0.93 9.5 0.0 3.6 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ORY44695.1 - 0.00012 22.6 0.1 0.092 13.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 ORY44695.1 - 0.00019 21.4 0.0 0.06 13.3 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain G-alpha PF00503.20 ORY44695.1 - 0.00047 19.4 0.0 0.046 12.9 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_21 PF13304.6 ORY44695.1 - 0.00061 19.7 0.0 0.53 10.1 0.0 3.8 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 ORY44695.1 - 0.00074 19.1 0.1 0.49 9.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region SbcCD_C PF13558.6 ORY44695.1 - 0.00083 19.5 5.5 0.43 10.8 0.5 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.6 ORY44695.1 - 0.00096 18.8 1.5 1.4 8.4 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_15 PF13175.6 ORY44695.1 - 0.002 17.9 0.4 0.078 12.7 0.0 2.5 3 0 0 3 3 2 1 AAA ATPase domain Zeta_toxin PF06414.12 ORY44695.1 - 0.0025 17.1 1.8 0.24 10.7 0.0 3.5 4 0 0 4 4 3 1 Zeta toxin APS_kinase PF01583.20 ORY44695.1 - 0.0026 17.7 0.1 0.12 12.2 0.1 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_24 PF13479.6 ORY44695.1 - 0.0029 17.3 0.0 1.1 9.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 ORY44695.1 - 0.0039 17.3 0.3 0.54 10.3 0.1 3.7 3 0 0 3 3 3 1 Helicase HerA, central domain DUF815 PF05673.13 ORY44695.1 - 0.0059 15.8 0.1 0.73 9.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 ORY44695.1 - 0.0061 16.9 0.0 4.1 7.8 0.0 3.0 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.23 ORY44695.1 - 0.0061 16.6 0.3 4.4 7.4 0.1 3.0 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_23 PF13476.6 ORY44695.1 - 0.0063 17.0 7.5 5 7.6 0.0 3.5 3 0 0 3 3 3 0 AAA domain NACHT PF05729.12 ORY44695.1 - 0.0064 16.4 0.0 4.5 7.2 0.0 2.7 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 ORY44695.1 - 0.01 15.0 0.0 4.6 6.3 0.0 2.6 3 0 0 3 3 2 0 NB-ARC domain IstB_IS21 PF01695.17 ORY44695.1 - 0.02 14.7 1.2 20 4.9 0.0 3.5 3 0 0 3 3 3 0 IstB-like ATP binding protein PRK PF00485.18 ORY44695.1 - 0.053 13.2 0.0 7.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_19 PF13245.6 ORY44695.1 - 0.055 13.8 1.2 4.4 7.6 0.0 3.1 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 ORY44695.1 - 0.082 12.7 0.1 15 5.3 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 ORY44695.1 - 0.1 12.6 0.0 35 4.4 0.0 3.4 4 0 0 4 4 3 0 AAA domain AAA_33 PF13671.6 ORY44695.1 - 0.19 11.9 7.9 1.1 9.5 0.2 3.2 3 1 0 3 3 2 0 AAA domain AAA_17 PF13207.6 ORY44695.1 - 0.8 10.1 3.5 23 5.4 0.0 3.6 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.25 ORY44695.1 - 1.1 8.9 6.4 30 4.2 0.0 3.7 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain Syntaphilin PF15290.6 ORY44695.1 - 2.4 7.7 7.2 4.1 7.0 5.6 2.0 1 1 1 2 2 2 0 Golgi-localised syntaxin-1-binding clamp NTPase_1 PF03266.15 ORY44695.1 - 4.1 7.3 6.2 25 4.7 0.1 3.8 4 0 0 4 4 4 0 NTPase Yip1 PF04893.17 ORY44695.1 - 8.3 6.1 19.2 14 5.4 2.6 3.5 3 1 0 3 3 3 0 Yip1 domain MSC PF09402.10 ORY44697.1 - 2.3e-24 86.5 0.2 2.9e-24 86.2 0.2 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain Peripla_BP_5 PF13433.6 ORY44697.1 - 0.047 12.7 0.0 0.059 12.3 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein domain GBP PF02263.19 ORY44697.1 - 0.07 12.4 0.0 0.086 12.1 0.0 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain His_Phos_1 PF00300.22 ORY44698.1 - 6.8e-13 48.7 0.0 8.1e-13 48.5 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF498 PF04430.14 ORY44699.1 - 1.9e-29 101.9 0.0 2.9e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) DUF726 PF05277.12 ORY44701.1 - 6.5e-79 265.3 0.0 8.3e-79 265.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) DUF5427 PF10310.9 ORY44701.1 - 0.00027 20.0 3.5 0.00036 19.6 3.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5427) LCAT PF02450.15 ORY44701.1 - 0.029 13.5 0.0 0.037 13.2 0.0 1.3 1 1 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF3089 PF11288.8 ORY44701.1 - 0.097 12.2 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF664 PF04978.12 ORY44701.1 - 0.15 12.4 0.7 0.25 11.8 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF664) Polysacc_synt_C PF14667.6 ORY44701.1 - 0.27 11.3 1.7 0.72 9.9 0.3 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain PIEZO PF15917.5 ORY44701.1 - 0.8 9.1 4.8 1.2 8.6 4.8 1.1 1 0 0 1 1 1 0 Piezo Hid1 PF12722.7 ORY44701.1 - 0.8 7.8 3.6 1.1 7.4 3.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 ORY44701.1 - 3.7 5.7 7.4 5.3 5.2 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein TPR_19 PF14559.6 ORY44703.1 - 1.5e-16 60.7 15.7 6.7e-06 26.5 2.1 6.5 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY44703.1 - 2e-14 52.4 29.9 0.0012 18.8 0.5 9.5 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 ORY44703.1 - 1.5e-13 51.1 3.5 4.5e-05 24.0 2.2 6.2 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORY44703.1 - 7.6e-11 42.2 11.6 0.42 10.9 1.4 7.4 6 3 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORY44703.1 - 7.3e-09 35.1 29.6 0.021 14.7 0.5 9.3 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY44703.1 - 7.6e-08 32.6 7.2 0.0033 18.1 1.0 6.8 6 2 2 8 8 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY44703.1 - 8.1e-08 32.4 24.0 0.0019 18.4 3.7 5.9 5 2 2 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 ORY44703.1 - 1.8e-06 27.5 12.5 0.01 15.8 0.2 8.0 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY44703.1 - 0.00013 21.9 22.0 0.66 10.3 0.0 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY44703.1 - 0.0018 18.8 21.4 0.017 15.8 0.3 6.8 8 1 0 8 8 7 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORY44703.1 - 0.0047 17.0 0.2 0.52 10.5 0.1 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY44703.1 - 0.011 16.0 13.2 0.42 11.1 1.5 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 ORY44703.1 - 0.013 15.5 20.9 0.65 10.0 0.5 5.7 4 2 2 6 6 6 0 Putative TPR-like repeat DUF285 PF03382.14 ORY44703.1 - 0.03 14.1 0.2 0.06 13.1 0.2 1.5 1 0 0 1 1 1 0 Mycoplasma protein of unknown function, DUF285 Sec16_C PF12931.7 ORY44703.1 - 0.041 13.5 0.2 0.11 12.1 0.2 1.7 1 0 0 1 1 1 0 Sec23-binding domain of Sec16 TPR_20 PF14561.6 ORY44703.1 - 0.15 12.4 4.7 3.9 7.9 0.0 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY44703.1 - 1.7 8.8 21.6 0.48 10.5 0.2 5.0 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat DUF1266 PF06889.11 ORY44703.1 - 3.1 7.8 5.1 0.93 9.5 0.5 2.3 3 0 0 3 3 2 0 Protein of unknown function (DUF1266) Sel1 PF08238.12 ORY44704.1 - 1.6e-24 85.7 1.1 2.6e-06 27.9 0.0 5.3 5 0 0 5 5 5 3 Sel1 repeat TPR_6 PF13174.6 ORY44704.1 - 0.00025 21.5 0.9 19 6.2 0.4 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat dUTPase PF00692.19 ORY44705.1 - 1.4e-44 150.8 0.0 1.7e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 dUTPase FtsZ_C PF12327.8 ORY44705.1 - 0.038 14.3 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 FtsZ family, C-terminal domain Peptidase_M36 PF02128.15 ORY44706.1 - 7.9e-136 453.1 5.9 9.8e-136 452.8 5.9 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) Peptidase_M50B PF13398.6 ORY44706.1 - 0.019 14.6 0.2 0.046 13.3 0.2 1.6 1 0 0 1 1 1 0 Peptidase M50B-like Rxt3 PF08642.10 ORY44707.1 - 2.4e-22 80.1 0.3 1.4e-21 77.6 0.0 2.1 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 ORY44707.1 - 0.047 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 LCCL domain MMR_HSR1 PF01926.23 ORY44708.1 - 0.00014 21.9 0.1 0.00049 20.2 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 ORY44708.1 - 0.011 15.8 0.1 0.058 13.4 0.1 2.4 1 1 0 1 1 1 0 Dynamin family AAA_14 PF13173.6 ORY44708.1 - 0.011 15.8 0.3 0.077 13.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 ORY44708.1 - 0.028 13.8 0.0 0.084 12.3 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 ORY44708.1 - 0.068 13.5 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF1828 PF08861.10 ORY44708.1 - 0.12 12.7 0.1 0.36 11.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF1828 MMR_HSR1 PF01926.23 ORY44709.1 - 8.5e-06 25.8 0.0 9.8e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 ORY44709.1 - 0.0017 18.5 0.0 0.49 10.4 0.0 2.0 1 1 1 2 2 2 2 Dynamin family SRPRB PF09439.10 ORY44709.1 - 0.0034 16.9 0.0 0.0038 16.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 ORY44709.1 - 0.0043 17.3 0.0 0.0048 17.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 ORY44709.1 - 0.031 14.3 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 ORY44709.1 - 0.065 12.8 0.2 0.27 10.7 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 ORY44709.1 - 0.089 13.3 0.0 0.097 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ORY44710.1 - 3.9e-06 26.9 0.0 4.4e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 ORY44710.1 - 0.0022 18.1 0.0 0.42 10.6 0.0 2.0 1 1 1 2 2 2 2 Dynamin family AAA_22 PF13401.6 ORY44710.1 - 0.0041 17.4 0.0 0.0046 17.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.10 ORY44710.1 - 0.0043 16.5 0.0 0.0048 16.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.6 ORY44710.1 - 0.03 14.3 0.0 0.036 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 ORY44710.1 - 0.052 13.1 0.1 0.27 10.7 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 ORY44710.1 - 0.1 13.2 0.0 0.11 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ORY44711.1 - 8.5e-06 25.8 0.0 9.8e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 ORY44711.1 - 0.0017 18.5 0.0 0.49 10.4 0.0 2.0 1 1 1 2 2 2 2 Dynamin family SRPRB PF09439.10 ORY44711.1 - 0.0034 16.9 0.0 0.0038 16.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 ORY44711.1 - 0.0043 17.3 0.0 0.0048 17.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 ORY44711.1 - 0.031 14.3 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 ORY44711.1 - 0.065 12.8 0.2 0.27 10.7 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 ORY44711.1 - 0.089 13.3 0.0 0.097 13.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain LRR_8 PF13855.6 ORY44712.1 - 1.6e-15 56.6 36.2 1.2e-07 31.4 10.8 4.3 3 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 ORY44712.1 - 1.7e-13 50.5 25.7 9.3e-05 22.7 5.0 5.3 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY44712.1 - 0.00085 19.6 25.1 0.15 12.7 0.2 7.3 7 2 1 8 8 8 2 Leucine Rich Repeat Ribosomal_L32e PF01655.18 ORY44712.1 - 0.082 13.3 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L32 DUF5612 PF18462.1 ORY44712.1 - 0.12 12.2 0.1 18 5.1 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5612) LRR_9 PF14580.6 ORY44712.1 - 0.14 11.7 4.5 9.8 5.6 1.5 3.0 2 1 1 3 3 3 0 Leucine-rich repeat LRR_6 PF13516.6 ORY44712.1 - 0.21 11.7 19.1 39 4.7 1.4 6.9 7 0 0 7 7 7 0 Leucine Rich repeat Rhomboid PF01694.22 ORY44713.1 - 2e-20 73.3 16.8 3.5e-20 72.5 16.8 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 ORY44713.1 - 0.0076 16.8 4.0 0.0076 16.8 4.0 2.2 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) DUF5326 PF17260.2 ORY44713.1 - 0.49 10.6 6.6 0.3 11.2 3.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5326) Velvet PF11754.8 ORY44714.1 - 6.1e-35 121.4 0.1 2e-30 106.5 0.0 2.1 1 1 1 2 2 2 2 Velvet factor Myotub-related PF06602.14 ORY44715.1 - 2.1e-144 480.8 0.0 2.5e-144 480.6 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 ORY44715.1 - 0.027 14.0 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 ORY44715.1 - 0.057 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF501 PF04417.12 ORY44716.1 - 0.016 15.0 0.2 0.029 14.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF501) DUF3395 PF11875.8 ORY44716.1 - 0.12 12.2 1.1 0.42 10.5 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3395) OPT PF03169.15 ORY44717.1 - 2.7e-110 369.9 44.3 3e-109 366.4 44.3 1.9 1 1 0 1 1 1 1 OPT oligopeptide transporter protein DUF2109 PF09882.9 ORY44717.1 - 1 9.4 4.2 10 6.2 0.0 3.4 3 0 0 3 3 3 0 Predicted membrane protein (DUF2109) Glyco_hydro_47 PF01532.20 ORY44718.1 - 9.2e-140 466.5 0.2 1.8e-139 465.6 0.2 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 NUC153 PF08159.12 ORY44720.1 - 4e-12 45.7 0.5 8.9e-12 44.6 0.5 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 ORY44720.1 - 3.2e-06 27.8 0.0 0.11 13.4 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY44720.1 - 0.00072 19.8 0.0 0.42 10.9 0.0 3.6 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_22 PF18833.1 ORY44720.1 - 0.044 13.9 0.8 0.13 12.5 0.8 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat SNF2_N PF00176.23 ORY44722.1 - 7.8e-52 176.1 0.0 1.1e-51 175.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY44722.1 - 4.9e-22 78.4 0.0 1.1e-21 77.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 ORY44722.1 - 1.5e-16 60.4 0.0 3.3e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 ORY44722.1 - 4.7e-11 43.0 0.0 9.2e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ORY44722.1 - 0.00036 19.8 0.0 0.0006 19.1 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase KRAB PF01352.27 ORY44722.1 - 0.0052 16.4 0.0 0.015 14.9 0.0 1.8 1 0 0 1 1 1 1 KRAB box Ribul_P_3_epim PF00834.19 ORY44722.1 - 0.072 12.5 0.0 0.39 10.1 0.0 2.0 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family AAA_22 PF13401.6 ORY44722.1 - 0.083 13.2 0.0 0.26 11.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain Chromo PF00385.24 ORY44723.1 - 5.4e-13 48.6 0.8 1.6e-11 44.0 0.1 2.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 ORY44723.1 - 0.002 18.2 0.3 0.73 10.0 0.0 2.5 2 0 0 2 2 2 2 Chromo shadow domain Mtf2_C PF14061.6 ORY44723.1 - 0.064 13.4 0.0 0.77 10.0 0.0 2.3 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 SMYLE_N PF18615.1 ORY44725.1 - 2.5 7.6 6.9 0.23 11.0 0.8 2.1 2 1 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain PI3K_1B_p101 PF10486.9 ORY44725.1 - 3.8 5.2 9.3 0.18 9.5 3.2 1.7 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DDOST_48kD PF03345.14 ORY44726.1 - 2.7e-124 415.2 1.6 3.3e-124 414.9 1.6 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Methyltransf_25 PF13649.6 ORY44727.1 - 2.5e-13 50.5 0.0 1.1e-12 48.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Dala_Dala_lig_C PF07478.13 ORY44727.1 - 1.4e-12 47.6 0.0 3.5e-12 46.3 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Methyltransf_31 PF13847.6 ORY44727.1 - 9.2e-11 41.8 0.0 2.1e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY44727.1 - 4.1e-10 40.2 0.0 1.2e-09 38.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY44727.1 - 6.3e-07 29.1 0.0 4.9e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 ORY44727.1 - 6.4e-06 26.1 0.0 0.00038 20.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY44727.1 - 9e-06 25.2 0.0 2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 ORY44727.1 - 6.4e-05 22.5 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.14 ORY44727.1 - 0.00041 19.8 0.0 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 Tellurite resistance protein TehB ATP-grasp_3 PF02655.14 ORY44727.1 - 0.0078 16.3 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Methyltransf_12 PF08242.12 ORY44727.1 - 0.013 16.2 0.0 0.047 14.4 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain ATP-grasp_4 PF13535.6 ORY44727.1 - 0.086 12.4 0.0 0.31 10.6 0.0 1.9 2 1 0 2 2 2 0 ATP-grasp domain WW PF00397.26 ORY44728.1 - 3.5e-25 87.8 4.7 5.7e-12 45.5 1.0 2.3 2 0 0 2 2 2 2 WW domain EF_assoc_1 PF08355.12 ORY44728.1 - 0.12 12.0 0.9 8 6.1 0.1 2.4 2 0 0 2 2 2 0 EF hand associated EDR1 PF14381.6 ORY44729.1 - 9.3e-14 51.6 0.0 2.2e-13 50.4 0.0 1.6 1 1 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 Guanylate_cyc PF00211.20 ORY44730.1 - 3.2e-28 98.6 0.0 4.8e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain MazG-like PF12643.7 ORY44730.1 - 0.041 14.1 0.0 0.082 13.2 0.0 1.4 1 0 0 1 1 1 0 MazG-like family FlxA PF14282.6 ORY44730.1 - 0.16 12.0 1.7 0.28 11.2 0.1 2.0 2 0 0 2 2 2 0 FlxA-like protein Cep57_MT_bd PF06657.13 ORY44730.1 - 0.65 10.5 3.0 0.36 11.3 0.9 1.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Guanylate_cyc PF00211.20 ORY44732.1 - 4.1e-46 156.9 0.2 5.1e-46 156.6 0.2 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF2521 PF10730.9 ORY44732.1 - 0.029 14.4 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2521) DUF603 PF04645.12 ORY44732.1 - 0.06 13.1 0.1 0.083 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF603 Guanylate_cyc PF00211.20 ORY44735.1 - 2.6e-44 151.1 0.8 1e-22 80.6 0.1 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain CENP-O PF09496.10 ORY44736.1 - 0.017 15.1 3.4 0.017 15.1 3.4 1.1 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component Erp_C PF06780.11 ORY44736.1 - 0.02 14.9 0.6 0.025 14.6 0.6 1.2 1 0 0 1 1 1 0 Erp protein C-terminus DUF2968 PF11180.8 ORY44736.1 - 0.08 12.6 6.4 0.097 12.3 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) HalX PF08663.10 ORY44736.1 - 0.21 11.9 2.9 0.14 12.4 1.2 1.6 2 0 0 2 2 2 0 HalX domain KH_1 PF00013.29 ORY44737.1 - 1.5e-29 101.6 15.3 2.2e-17 62.6 0.3 4.3 3 1 1 4 4 4 3 KH domain KH_2 PF07650.17 ORY44737.1 - 2.7e-09 36.7 6.4 0.0054 16.5 0.5 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 ORY44737.1 - 1.8e-05 24.5 5.3 0.044 13.6 0.2 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 ORY44737.1 - 0.014 15.4 6.7 0.18 11.9 0.4 2.7 3 0 0 3 3 3 0 NusA-like KH domain Guanylate_cyc PF00211.20 ORY44738.1 - 1.5e-50 171.3 0.2 2.3e-50 170.7 0.2 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF2521 PF10730.9 ORY44738.1 - 0.028 14.5 0.3 0.077 13.0 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2521) Guanylate_cyc PF00211.20 ORY44739.1 - 7.7e-28 97.4 0.1 9.2e-28 97.1 0.1 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF2521 PF10730.9 ORY44739.1 - 0.0083 16.2 0.0 0.011 15.7 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2521) SH3_1 PF00018.28 ORY44741.1 - 3.6e-07 29.7 0.0 6.1e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY44741.1 - 2.1e-06 27.5 0.0 4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Arrestin_C PF02752.22 ORY44741.1 - 1.1e-05 25.9 0.0 2.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY44741.1 - 0.025 14.7 0.1 0.093 12.8 0.0 2.0 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain SH3_2 PF07653.17 ORY44741.1 - 0.034 13.8 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain DUF4820 PF16091.5 ORY44742.1 - 0.18 11.1 0.2 0.3 10.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) HTH_DeoR PF08220.12 ORY44743.1 - 0.053 13.3 0.8 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 DeoR-like helix-turn-helix domain UPF0767 PF15990.5 ORY44743.1 - 0.11 12.7 0.3 0.22 11.7 0.0 1.6 1 1 1 2 2 2 0 UPF0767 family Peptidase_M14 PF00246.24 ORY44744.1 - 2.4e-16 60.4 0.0 2.2e-15 57.2 0.0 2.1 2 0 0 2 2 2 1 Zinc carboxypeptidase AstE_AspA PF04952.14 ORY44744.1 - 0.0055 15.8 0.0 0.0076 15.4 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family GGACT PF06094.12 ORY44745.1 - 2.6e-08 34.5 0.0 3.9e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like ABC_tran PF00005.27 ORY44747.1 - 2.1e-38 131.9 0.0 8.4e-29 100.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ORY44747.1 - 1.8e-21 77.2 0.0 1.3e-08 35.1 0.0 3.9 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 ORY44747.1 - 2.9e-18 66.1 52.3 2.8e-11 43.2 23.0 2.8 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_15 PF13175.6 ORY44747.1 - 1.6e-09 38.0 0.0 0.13 12.0 0.0 3.6 2 1 1 3 3 3 3 AAA ATPase domain SMC_N PF02463.19 ORY44747.1 - 0.0005 19.6 0.0 0.18 11.2 0.0 3.0 2 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 ORY44747.1 - 0.047 13.4 0.1 0.098 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 ORY44747.1 - 0.085 13.1 0.0 16 5.8 0.0 3.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC2_membrane PF01061.24 ORY44747.1 - 0.73 9.2 51.1 1.1 8.7 23.3 4.3 4 1 0 4 4 4 0 ABC-2 type transporter Presenilin PF01080.17 ORY44749.1 - 6.2 5.5 5.6 7.4 5.2 5.6 1.1 1 0 0 1 1 1 0 Presenilin Methyltransf_23 PF13489.6 ORY44750.1 - 5.1e-16 58.9 0.0 7.4e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY44750.1 - 1.3e-15 57.7 0.0 6.1e-15 55.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY44750.1 - 3.4e-14 53.3 0.0 9.6e-13 48.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY44750.1 - 4e-09 37.1 0.0 9e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY44750.1 - 2.6e-08 33.5 0.0 2e-07 30.6 0.0 1.9 1 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 ORY44750.1 - 5.3e-08 32.8 0.1 5e-07 29.6 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain DREV PF05219.12 ORY44750.1 - 0.042 12.9 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase MetW PF07021.12 ORY44750.1 - 0.078 12.6 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW IMS_C PF11799.8 ORY44750.1 - 0.26 12.0 0.9 35 5.1 0.0 3.0 2 2 1 3 3 3 0 impB/mucB/samB family C-terminal domain Prefoldin_2 PF01920.20 ORY44751.1 - 3.8e-21 75.0 4.9 4.2e-21 74.9 4.9 1.0 1 0 0 1 1 1 1 Prefoldin subunit DASH_Dad3 PF08656.10 ORY44751.1 - 0.0013 18.7 0.4 0.074 13.2 0.0 2.1 2 0 0 2 2 2 1 DASH complex subunit Dad3 Prefoldin PF02996.17 ORY44751.1 - 0.0067 16.3 2.8 0.044 13.7 2.8 1.9 1 1 0 1 1 1 1 Prefoldin subunit Occludin_ELL PF07303.13 ORY44751.1 - 0.0071 17.0 2.2 0.88 10.3 0.2 2.1 2 0 0 2 2 2 2 Occludin homology domain SAPIS-gp6 PF16722.5 ORY44751.1 - 0.014 15.8 5.2 0.31 11.5 0.3 2.2 2 0 0 2 2 2 0 Pathogenicity island protein gp6 in Staphylococcus FliJ PF02050.16 ORY44751.1 - 0.029 14.6 4.1 1.7 8.8 0.4 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein Allexi_40kDa PF05549.11 ORY44751.1 - 0.058 12.9 2.1 0.3 10.6 0.3 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein PAS_10 PF13596.6 ORY44751.1 - 0.067 13.8 0.6 0.41 11.3 0.1 2.0 1 1 1 2 2 2 0 PAS domain Peptidase_M75 PF09375.10 ORY44751.1 - 0.075 12.5 1.2 0.55 9.7 0.4 1.9 2 0 0 2 2 2 0 Imelysin LXG PF04740.12 ORY44751.1 - 0.08 12.6 3.3 0.24 11.1 0.7 2.0 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF2408 PF10303.9 ORY44751.1 - 0.12 12.9 2.2 0.18 12.4 1.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) SKA2 PF16740.5 ORY44751.1 - 0.15 11.9 4.4 0.93 9.3 4.4 1.9 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Tup_N PF08581.10 ORY44751.1 - 0.15 12.4 4.1 0.59 10.5 0.9 2.1 2 0 0 2 2 2 0 Tup N-terminal Tho2 PF11262.8 ORY44751.1 - 0.28 10.4 3.7 3.2 6.9 0.1 2.0 1 1 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 FapA PF03961.13 ORY44751.1 - 0.79 8.3 5.5 0.23 10.0 0.8 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A OmpH PF03938.14 ORY44751.1 - 5.7 7.3 12.2 12 6.3 1.9 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Ank_2 PF12796.7 ORY44752.1 - 3.4e-10 40.4 0.0 0.0065 17.0 0.0 3.9 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY44752.1 - 9e-08 32.5 0.5 0.13 12.9 0.1 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY44752.1 - 3.8e-07 30.3 1.5 0.32 11.5 0.0 5.8 5 1 1 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 ORY44752.1 - 3.2e-06 27.3 1.0 0.069 13.5 0.1 5.0 3 2 2 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY44752.1 - 0.0038 17.6 1.2 28 5.7 0.0 5.5 7 0 0 7 7 7 1 Ankyrin repeat F-box PF00646.33 ORY44752.1 - 2.1 8.3 6.0 2.4 8.1 0.6 2.8 2 0 0 2 2 2 0 F-box domain Ank_2 PF12796.7 ORY44753.1 - 1.1e-12 48.3 0.0 1.3e-05 25.7 0.1 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY44753.1 - 1.5e-08 34.7 2.5 0.1 13.0 0.0 5.4 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY44753.1 - 1.4e-05 25.6 4.1 0.028 15.0 0.0 4.1 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY44753.1 - 3.4e-05 23.9 0.1 39 5.3 0.0 6.0 6 0 0 6 6 6 0 Ankyrin repeat Ank PF00023.30 ORY44753.1 - 0.00034 20.9 1.2 81 3.9 0.0 6.6 6 2 0 6 6 6 0 Ankyrin repeat RAMA PF18755.1 ORY44753.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 Restriction Enzyme Adenine Methylase Associated Ank_2 PF12796.7 ORY44754.1 - 3.6e-20 72.3 1.6 4.9e-06 27.0 0.2 4.5 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY44754.1 - 4.7e-20 71.7 0.5 6.1e-06 26.7 0.1 5.9 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY44754.1 - 3.6e-18 65.4 2.8 0.03 14.6 0.0 7.6 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY44754.1 - 2.3e-13 49.0 1.4 2.2 9.1 0.0 8.1 6 2 2 8 8 8 4 Ankyrin repeat Ank PF00023.30 ORY44754.1 - 0.00013 22.2 3.0 15 6.2 0.0 6.9 5 2 2 7 7 7 1 Ankyrin repeat FBD PF08387.10 ORY44754.1 - 0.0016 18.3 1.2 7.3 6.6 0.0 4.5 3 1 1 4 4 4 1 FBD AMPK1_CBM PF16561.5 ORY44755.1 - 8e-06 26.0 0.1 1.5e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DUF4674 PF15719.5 ORY44755.1 - 10 6.1 10.4 35 4.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4674) AMPK1_CBM PF16561.5 ORY44756.1 - 0.00032 20.9 0.0 0.00051 20.2 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase RRM_1 PF00076.22 ORY44757.1 - 1.4e-15 56.8 0.0 1.8e-08 34.1 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GBP_C PF02841.14 ORY44758.1 - 0.025 14.0 2.4 0.042 13.3 0.9 2.0 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain CAP_N PF01213.19 ORY44758.1 - 0.042 13.3 7.8 0.11 11.9 0.8 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Nitr_red_assoc PF09655.10 ORY44758.1 - 0.19 12.4 1.1 0.44 11.2 0.6 1.8 2 0 0 2 2 2 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) PRIMA1 PF16101.5 ORY44758.1 - 0.3 11.1 7.4 0.77 9.8 7.4 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 KASH_CCD PF14662.6 ORY44758.1 - 0.35 10.7 6.0 0.094 12.5 1.3 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Fib_alpha PF08702.10 ORY44758.1 - 10 6.3 7.8 1.3 9.2 1.3 2.5 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family THUMP PF02926.17 ORY44759.1 - 0.0021 18.2 0.3 0.0021 18.2 0.3 2.5 3 0 0 3 3 3 1 THUMP domain DUF3727 PF12527.8 ORY44759.1 - 0.62 10.3 3.6 1.6 9.1 3.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3727) FAM176 PF14851.6 ORY44759.1 - 5.9 6.5 8.3 2.2 7.9 1.8 2.4 2 0 0 2 2 2 0 FAM176 family F1F0-ATPsyn_F PF10791.9 ORY44761.1 - 7.8e-06 26.3 2.8 0.00022 21.6 2.8 2.2 1 1 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi Adaptin_N PF01602.20 ORY44762.1 - 3.3e-110 369.1 6.5 5.9e-110 368.3 6.5 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_g_Cpla PF16381.5 ORY44762.1 - 3.5e-37 127.0 0.0 1e-36 125.6 0.0 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform COP-gamma_platf PF08752.10 ORY44762.1 - 4e-36 124.4 2.7 5.3e-35 120.8 0.4 3.1 2 1 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.6 ORY44762.1 - 3.4e-11 43.4 3.5 1.1e-06 28.9 0.0 5.3 4 1 2 6 6 6 1 HEAT repeats Cnd1 PF12717.7 ORY44762.1 - 6.1e-09 36.1 4.9 0.0016 18.5 0.1 3.7 3 1 0 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 ORY44762.1 - 0.068 13.9 0.6 1.2e+02 3.8 0.0 4.5 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat HEAT PF02985.22 ORY44762.1 - 1.2 9.6 5.0 3e+02 2.1 0.1 5.6 5 0 0 5 5 5 0 HEAT repeat Response_reg PF00072.24 ORY44763.1 - 3.7e-08 33.5 0.4 6.5e-06 26.3 0.1 2.3 2 0 0 2 2 2 2 Response regulator receiver domain DUF1694 PF07997.11 ORY44763.1 - 0.11 12.6 0.2 0.38 10.8 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1694) Response_reg PF00072.24 ORY44764.1 - 3.4e-09 36.9 1.9 3.3e-07 30.5 0.4 2.4 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 ORY44764.1 - 1.6e-06 28.6 0.0 5.8e-06 26.8 0.0 1.9 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_1 PF00515.28 ORY44765.1 - 2.9e-06 26.9 0.0 0.054 13.3 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY44765.1 - 2.8e-05 23.8 0.8 0.36 11.0 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY44765.1 - 0.00032 20.6 1.9 2 8.7 0.2 4.0 4 0 0 4 4 3 1 Tetratricopeptide repeat DnaJ PF00226.31 ORY44765.1 - 0.00059 19.9 0.0 0.0016 18.5 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain UBA PF00627.31 ORY44765.1 - 0.016 15.1 0.2 0.2 11.6 0.0 2.8 2 0 0 2 2 2 0 UBA/TS-N domain DUF349 PF03993.12 ORY44765.1 - 0.027 14.8 3.3 0.1 12.9 3.3 2.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) COQ7 PF03232.13 ORY44765.1 - 0.064 13.0 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 TPR_6 PF13174.6 ORY44765.1 - 0.14 12.9 1.5 9.4 7.1 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY44765.1 - 1.1 10.0 5.4 2.8 8.7 0.0 3.1 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY44765.1 - 1.1 9.6 5.7 2 8.8 0.0 2.9 2 1 1 3 3 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY44765.1 - 2.3 9.2 5.3 48 5.1 0.1 3.5 2 1 2 4 4 3 0 Tetratricopeptide repeat L51_S25_CI-B8 PF05047.16 ORY44766.1 - 0.039 13.9 0.0 0.066 13.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain cNMP_binding PF00027.29 ORY44767.1 - 1.1e-14 54.3 0.1 2.4e-14 53.1 0.1 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain CSRNP_N PF16019.5 ORY44767.1 - 0.26 11.2 2.5 7.4 6.4 0.6 2.4 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus FadA PF09403.10 ORY44767.1 - 0.47 11.0 5.7 16 6.0 0.0 2.5 2 0 0 2 2 2 0 Adhesion protein FadA OPT PF03169.15 ORY44768.1 - 4.9e-126 421.8 48.0 4.8e-123 411.9 48.0 2.0 1 1 0 1 1 1 1 OPT oligopeptide transporter protein SOG2 PF10428.9 ORY44768.1 - 8.8 5.4 12.4 12 4.9 12.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein OPT PF03169.15 ORY44769.1 - 4.9e-120 402.0 42.7 8.9e-120 401.2 42.7 1.4 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Mito_carr PF00153.27 ORY44770.1 - 4.5e-10 39.3 1.1 0.0046 16.8 0.0 4.3 4 0 0 4 4 4 3 Mitochondrial carrier protein PAP_central PF04928.17 ORY44771.1 - 1.8e-59 200.8 0.0 2.8e-59 200.1 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 ORY44771.1 - 3.5e-22 78.8 0.0 2.8e-14 53.1 0.0 2.2 1 1 1 2 2 2 2 Poly(A) polymerase predicted RNA binding domain BRAP2 PF07576.12 ORY44772.1 - 4.1e-28 97.5 0.0 9.1e-28 96.4 0.0 1.5 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 ORY44772.1 - 2e-19 69.7 4.9 4.1e-19 68.7 4.9 1.5 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 ORY44772.1 - 0.17 11.6 0.8 0.41 10.4 0.8 1.6 1 0 0 1 1 1 0 Variant UBP zinc finger Ufd2P_core PF10408.9 ORY44773.1 - 2.4e-191 637.6 0.0 2.8e-191 637.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 ORY44773.1 - 5.6e-18 64.9 3.0 1.4e-17 63.6 3.0 1.7 1 0 0 1 1 1 1 U-box domain DUF3276 PF11680.8 ORY44773.1 - 0.12 12.5 0.2 0.31 11.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) ATG22 PF11700.8 ORY44774.1 - 2.8e-51 174.7 19.1 1e-24 87.0 0.5 3.1 2 1 1 3 3 3 3 Vacuole effluxer Atg22 like Peptidase_M24 PF00557.24 ORY44776.1 - 3.6e-53 180.4 0.0 5.6e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 ORY44776.1 - 4.5e-25 87.8 0.0 9.5e-25 86.7 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain TSP_NTD PF17804.1 ORY44778.1 - 0.09 13.0 6.1 0.1 12.8 6.1 1.1 1 0 0 1 1 1 0 Tail specific protease N-terminal domain DDE_Tnp_4 PF13359.6 ORY44780.1 - 0.0033 17.1 0.0 0.0054 16.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease SNF2_N PF00176.23 ORY44781.1 - 1.2e-49 169.0 0.0 2.6e-49 167.8 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY44781.1 - 7e-15 55.3 0.1 6.5e-14 52.2 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY44781.1 - 1.2e-07 31.9 0.0 5.7e-07 29.7 0.0 2.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SAM_1 PF00536.30 ORY44781.1 - 1.7e-05 25.2 0.0 4.2e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ERCC3_RAD25_C PF16203.5 ORY44781.1 - 0.0018 17.5 1.2 0.003 16.8 0.3 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Aminotran_5 PF00266.19 ORY44782.1 - 1e-25 90.5 0.0 1.3e-25 90.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ORY44782.1 - 0.00072 18.2 0.0 0.0011 17.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme PcrB PF01884.17 ORY44782.1 - 0.067 12.6 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 PcrB family RPN6_N PF18055.1 ORY44783.1 - 2.7e-36 124.5 0.7 1e-35 122.6 0.7 2.0 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 ORY44783.1 - 2.2e-19 69.9 0.2 2.5e-18 66.5 0.2 2.5 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 ORY44783.1 - 4.9e-15 55.0 2.3 2.8e-14 52.5 0.7 2.7 2 0 0 2 2 2 1 26S proteasome subunit RPN6 C-terminal helix domain RPN7 PF10602.9 ORY44783.1 - 0.008 15.9 0.2 0.021 14.5 0.2 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_1 PF00515.28 ORY44783.1 - 0.4 10.6 5.1 6.7 6.7 0.6 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat SKIP_SNW PF02731.15 ORY44784.1 - 4.7e-71 237.6 1.8 4.7e-71 237.6 1.8 2.4 2 0 0 2 2 2 1 SKIP/SNW domain Nucleo_P87 PF07267.11 ORY44784.1 - 0.48 9.2 3.0 0.77 8.5 3.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Cwf_Cwc_15 PF04889.12 ORY44784.1 - 0.97 9.1 22.2 0.22 11.2 15.8 2.5 2 1 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein T4SS-DNA_transf PF02534.14 ORY44784.1 - 1.7 7.3 4.1 1.5 7.5 0.2 2.1 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Glyco_transf_8 PF01501.20 ORY44785.1 - 5.6e-11 42.5 0.0 8.4e-10 38.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 ORY44785.1 - 0.035 14.1 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.8 ORY44785.1 - 0.061 12.7 0.1 0.12 11.7 0.1 1.4 2 0 0 2 2 2 0 Mannosyltransferase putative DUF273 PF03314.14 ORY44785.1 - 0.23 11.0 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF273 Caudo_TAP PF02413.17 ORY44785.1 - 0.25 11.5 0.0 0.42 10.8 0.0 1.3 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK ThiF PF00899.21 ORY44786.1 - 7.5e-60 202.3 0.1 1.1e-59 201.8 0.1 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 ORY44786.1 - 8.1e-11 42.4 0.0 7.6e-10 39.3 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 ORY44786.1 - 0.00039 20.5 0.2 0.0064 16.6 0.1 2.5 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 ORY44786.1 - 0.011 15.0 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Ldh_1_N PF00056.23 ORY44786.1 - 0.02 15.0 0.1 0.039 14.0 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 ORY44786.1 - 0.039 14.4 0.1 0.099 13.1 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding DAO PF01266.24 ORY44786.1 - 0.19 11.3 0.1 0.33 10.5 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ribosomal_L27 PF01016.19 ORY44787.1 - 1.4e-30 105.1 0.6 2.2e-30 104.5 0.6 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein SNF2_N PF00176.23 ORY44788.1 - 3.9e-64 216.6 0.4 3.1e-62 210.3 0.1 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY44788.1 - 2.1e-20 73.1 0.1 7.9e-20 71.3 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY44788.1 - 8e-08 32.5 0.0 3.9e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY44788.1 - 2.2e-06 27.5 0.0 4.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBINO PF13892.6 ORY44788.1 - 0.0056 17.0 2.8 0.0056 17.0 2.8 2.2 2 0 0 2 2 2 1 DNA-binding domain ERCC3_RAD25_C PF16203.5 ORY44788.1 - 0.011 15.0 0.0 0.011 15.0 0.0 1.9 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase EST1 PF10374.9 ORY44790.1 - 2.9e-18 66.8 0.0 7.3e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Telomerase activating protein Est1 EST1_DNA_bind PF10373.9 ORY44790.1 - 1.4e-15 57.6 0.3 2.3e-14 53.5 0.3 2.2 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain Thiol_cytolys_C PF17440.2 ORY44790.1 - 0.22 11.7 1.4 19 5.5 0.5 2.3 2 0 0 2 2 2 0 Thiol-activated cytolysin beta sandwich domain CYTH PF01928.21 ORY44791.1 - 0.1 12.5 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 CYTH domain C2-C2_1 PF11618.8 ORY44791.1 - 0.16 12.0 0.0 0.17 12.0 0.0 1.1 1 0 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 AATase PF07247.12 ORY44792.1 - 0.066 11.8 1.4 0.6 8.6 0.0 2.7 3 0 0 3 3 3 0 Alcohol acetyltransferase WES_acyltransf PF03007.16 ORY44792.1 - 0.11 12.3 0.0 0.34 10.6 0.0 1.9 2 0 0 2 2 2 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Glyco_hydro_114 PF03537.13 ORY44793.1 - 2.7e-58 197.0 0.0 3.4e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Acetyltransf_1 PF00583.25 ORY44794.1 - 2e-12 47.4 0.0 2.8e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY44794.1 - 5.3e-09 36.1 0.0 7.5e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY44794.1 - 1.3e-08 35.1 0.0 1.8e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY44794.1 - 5.2e-06 26.3 0.0 9e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 ORY44794.1 - 0.00025 21.1 0.0 0.00048 20.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ORY44794.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 ORY44794.1 - 0.18 11.3 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase zf-C3HC4 PF00097.25 ORY44795.1 - 4.2e-11 42.5 6.2 6.7e-11 41.9 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY44795.1 - 4.3e-10 39.8 7.9 6.4e-10 39.2 7.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORY44795.1 - 5.2e-10 39.0 3.9 8.5e-10 38.3 3.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY44795.1 - 1.2e-09 38.0 2.8 1.2e-09 38.0 2.8 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORY44795.1 - 7.4e-09 35.3 6.2 1.3e-08 34.5 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY44795.1 - 3.4e-07 30.3 7.2 5.5e-07 29.6 7.2 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 ORY44795.1 - 3.6e-07 30.0 4.8 5.6e-07 29.4 4.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY44795.1 - 4.9e-07 29.5 5.7 8.4e-07 28.8 5.7 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 ORY44795.1 - 6.2e-05 23.2 4.3 0.00012 22.3 4.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain Baculo_IE-1 PF05290.11 ORY44795.1 - 0.0016 18.4 1.9 0.0026 17.7 1.9 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-ANAPC11 PF12861.7 ORY44795.1 - 0.002 18.1 1.9 0.003 17.6 1.9 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 ORY44795.1 - 0.062 13.2 4.1 0.12 12.2 4.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Rad50_zn_hook PF04423.14 ORY44795.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 ORY44795.1 - 0.19 11.6 3.2 0.39 10.5 3.2 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 ORY44795.1 - 0.54 10.4 4.0 2.3 8.4 4.0 2.0 1 1 0 1 1 1 0 RING-variant domain SOG2 PF10428.9 ORY44795.1 - 0.56 9.3 12.4 0.68 9.1 12.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.9 ORY44795.1 - 2.1 6.8 3.2 2.5 6.5 3.2 1.1 1 0 0 1 1 1 0 Macoilin family IBR PF01485.21 ORY44795.1 - 2.2 8.6 8.2 5.1 7.4 4.7 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Kinesin PF00225.23 ORY44796.1 - 3.7e-91 305.5 0.0 9.3e-91 304.2 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY44796.1 - 6.4e-18 65.1 0.0 1.4e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding WD40 PF00400.32 ORY44797.1 - 2.1e-49 164.4 17.6 9.1e-10 39.0 0.6 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY44797.1 - 2.6e-24 85.3 2.0 4.6e-05 23.6 0.1 6.6 1 1 6 7 7 7 7 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY44797.1 - 9.3e-10 38.7 0.7 0.0038 17.1 0.1 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ORY44797.1 - 0.00012 21.1 0.2 0.23 10.4 0.1 3.5 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 ORY44797.1 - 0.005 15.6 0.0 1.1 8.0 0.0 2.8 3 0 0 3 3 3 2 Nup133 N terminal like WD40_like PF17005.5 ORY44797.1 - 0.0058 16.0 0.0 0.027 13.8 0.0 2.0 2 0 0 2 2 2 1 WD40-like domain PQ-loop PF04193.14 ORY44799.1 - 6.4e-25 86.7 3.4 5.5e-12 45.3 0.5 2.6 2 0 0 2 2 2 2 PQ loop repeat Thioredoxin PF00085.20 ORY44799.1 - 8.8e-18 64.2 0.1 1.6e-17 63.4 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY44799.1 - 0.00065 20.1 0.1 0.0014 19.1 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 ORY44799.1 - 0.061 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 AhpC/TSA family PQ-loop PF04193.14 ORY44800.1 - 1.8e-23 82.1 5.0 8.6e-13 47.9 0.3 2.7 2 0 0 2 2 2 2 PQ loop repeat Pkinase PF00069.25 ORY44801.1 - 9.4e-64 215.3 0.0 1.1e-63 215.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY44801.1 - 4.6e-48 163.8 0.0 5.1e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY44801.1 - 1.5e-06 27.3 0.0 3.1e-06 26.2 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase ABC1 PF03109.16 ORY44801.1 - 0.0057 16.8 0.0 0.0095 16.1 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Haspin_kinase PF12330.8 ORY44801.1 - 0.015 14.3 0.0 0.21 10.5 0.0 2.0 1 1 0 1 1 1 0 Haspin like kinase domain Abi_2 PF07751.11 ORY44801.1 - 0.18 12.1 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 Abi-like protein Kdo PF06293.14 ORY44801.1 - 0.2 11.0 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mito_carr PF00153.27 ORY44802.1 - 2.2e-58 194.2 4.6 4.2e-22 77.9 0.2 3.8 4 0 0 4 4 4 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 ORY44802.1 - 7.5e-10 37.7 2.4 1e-05 24.7 1.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 ORY44802.1 - 4.8e-08 32.3 0.1 1.2e-06 27.9 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 ORY44802.1 - 1.1e-07 32.2 0.8 1.9e-07 31.4 0.8 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 ORY44802.1 - 3.6e-07 29.4 1.0 0.00039 19.8 0.9 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 ORY44802.1 - 0.00058 19.7 0.2 0.015 15.1 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 ORY44802.1 - 0.013 15.8 0.1 0.06 13.7 0.1 1.9 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Elongin_A PF06881.11 ORY44803.1 - 5.1e-13 49.5 4.3 7.5e-13 48.9 4.3 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A NAM-associated PF14303.6 ORY44805.1 - 0.34 11.6 2.0 0.42 11.3 2.0 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain AF-4 PF05110.13 ORY44810.1 - 0.047 11.8 12.7 0.053 11.6 12.7 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein TP2 PF01254.18 ORY44810.1 - 4.1 8.0 8.1 3 8.4 6.7 1.6 1 1 1 2 2 2 0 Nuclear transition protein 2 VEGFR-2_TMD PF17988.1 ORY44811.1 - 8.8 5.9 7.3 1.5 8.3 0.9 2.3 2 0 0 2 2 2 0 VEGFR-2 Transmembrane domain zf-C3HC4_3 PF13920.6 ORY44813.1 - 5.8e-13 48.5 8.0 1.1e-12 47.6 8.0 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY44813.1 - 2.3e-05 24.2 9.7 8.4e-05 22.4 9.7 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 ORY44813.1 - 3.9e-05 23.9 7.4 7.7e-05 22.9 7.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 ORY44813.1 - 0.00065 19.6 7.1 0.001 19.0 7.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 ORY44813.1 - 0.016 15.1 10.0 0.032 14.1 6.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY44813.1 - 0.31 10.8 5.1 0.17 11.7 1.5 2.2 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_UBOX PF13445.6 ORY44813.1 - 0.53 10.4 8.3 12 6.0 4.1 2.5 2 0 0 2 2 2 0 RING-type zinc-finger GATA PF00320.27 ORY44814.1 - 2e-06 27.3 1.3 3.6e-06 26.5 1.3 1.5 1 0 0 1 1 1 1 GATA zinc finger Arrestin_C PF02752.22 ORY44815.1 - 2.5e-05 24.7 0.1 0.00019 21.9 0.0 2.6 3 1 1 4 4 4 1 Arrestin (or S-antigen), C-terminal domain FAM86 PF14904.6 ORY44815.1 - 0.056 13.5 0.3 0.23 11.6 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function Gram_pos_anchor PF00746.21 ORY44816.1 - 0.043 13.8 0.3 0.043 13.8 0.3 2.0 2 0 0 2 2 2 0 LPXTG cell wall anchor motif RIFIN PF02009.16 ORY44816.1 - 0.16 11.8 0.1 0.31 10.9 0.0 1.4 2 0 0 2 2 2 0 Rifin DUF3149 PF11346.8 ORY44816.1 - 8.2 6.1 6.3 0.37 10.5 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) Saf_2TM PF18303.1 ORY44817.1 - 0.049 13.2 0.2 0.098 12.2 0.2 1.4 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Yip1 PF04893.17 ORY44817.1 - 1.4 8.6 5.4 0.15 11.8 0.5 1.8 2 1 1 3 3 3 0 Yip1 domain Dala_Dala_lig_C PF07478.13 ORY44818.1 - 0.0011 18.6 0.1 0.0018 17.9 0.1 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Phage_Coat_B PF05356.11 ORY44818.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Phage Coat protein B DUF4336 PF14234.6 ORY44819.1 - 1.7e-05 24.2 0.1 2.9e-05 23.4 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4336) Lactamase_B_5 PF14597.6 ORY44819.1 - 0.039 13.4 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily PIRT PF15099.6 ORY44820.1 - 0.041 13.5 0.0 0.045 13.3 0.0 1.1 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Plasmod_dom_1 PF09715.10 ORY44821.1 - 0.067 13.3 0.0 0.091 12.8 0.0 1.1 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) 7TM_GPCR_Srv PF10323.9 ORY44822.1 - 0.0023 17.3 0.0 0.0025 17.2 0.0 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srv DUF1345 PF07077.11 ORY44822.1 - 0.04 13.6 0.0 0.047 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) OAD_gamma PF04277.13 ORY44823.1 - 0.016 15.8 0.1 0.029 14.9 0.1 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain LapA_dom PF06305.11 ORY44823.1 - 0.027 14.3 0.2 0.027 14.3 0.2 1.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Nuc_sug_transp PF04142.15 ORY44823.1 - 0.047 12.8 0.3 0.062 12.5 0.3 1.1 1 0 0 1 1 1 0 Nucleotide-sugar transporter CBP_BcsF PF11120.8 ORY44823.1 - 0.086 13.0 0.3 13 6.0 0.2 2.2 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF WD40 PF00400.32 ORY44824.1 - 3.4e-13 49.8 2.2 0.031 15.1 0.0 6.0 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY44824.1 - 9.7e-10 38.6 0.1 0.061 13.6 0.1 4.4 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain SRA1 PF07304.11 ORY44824.1 - 0.011 15.5 0.1 0.011 15.5 0.1 2.7 3 0 0 3 3 3 0 Steroid receptor RNA activator (SRA1) Ge1_WD40 PF16529.5 ORY44824.1 - 0.13 11.2 0.1 2.4 7.0 0.0 2.4 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Bac_GDH PF05088.12 ORY44824.1 - 0.16 9.5 0.1 0.22 9.0 0.1 1.1 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase COG5 PF10392.9 ORY44824.1 - 0.16 12.2 1.4 0.37 10.9 0.3 2.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 PikAIV_N PF18605.1 ORY44824.1 - 0.17 11.5 2.5 0.44 10.2 2.5 1.7 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain HATPase_c PF02518.26 ORY44825.1 - 1.7e-27 96.1 0.4 4.4e-27 94.8 0.4 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 ORY44825.1 - 9.9e-16 57.9 0.0 5.1e-15 55.6 0.0 2.3 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.7 ORY44825.1 - 9.8e-11 41.8 0.4 9.8e-11 41.8 0.4 3.1 4 0 0 4 4 4 1 PAS domain PAS PF00989.25 ORY44825.1 - 9.8e-10 38.4 0.1 9.8e-10 38.4 0.1 3.4 4 0 0 4 4 4 1 PAS fold HisKA PF00512.25 ORY44825.1 - 1.5e-07 31.3 2.9 2.9e-07 30.4 0.3 3.0 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 ORY44825.1 - 5.6e-07 29.8 0.4 2.9e-05 24.3 0.0 3.1 2 1 1 3 3 3 1 PAS fold PAS_8 PF13188.7 ORY44825.1 - 0.0035 17.3 0.0 0.0095 15.9 0.0 1.7 1 0 0 1 1 1 1 PAS domain HATPase_c_3 PF13589.6 ORY44825.1 - 0.0045 16.8 0.1 0.023 14.6 0.1 2.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SecE PF00584.20 ORY44826.1 - 1.1e-14 54.1 0.2 1.3e-14 53.9 0.2 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex CbtB PF09489.10 ORY44826.1 - 0.055 13.6 0.2 0.069 13.3 0.2 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) Cofilin_ADF PF00241.20 ORY44827.1 - 4.2e-34 117.0 0.1 4.8e-34 116.8 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Toprim_C_rpt PF13368.6 ORY44827.1 - 4.1 7.5 6.0 75 3.4 0.1 3.1 3 0 0 3 3 3 0 Topoisomerase C-terminal repeat Pro_isomerase PF00160.21 ORY44829.1 - 2e-24 86.6 0.0 3.2e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 ORY44831.1 - 4.5e-08 32.6 9.2 0.0095 16.0 1.4 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 ORY44831.1 - 8.5e-07 29.4 3.9 0.035 14.6 0.2 3.5 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY44831.1 - 3.2e-05 23.8 4.3 1.6 9.2 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY44831.1 - 0.00013 22.5 8.5 0.058 14.2 1.0 4.1 2 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY44831.1 - 0.00025 21.2 10.1 0.2 12.0 1.2 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORY44831.1 - 0.0015 18.2 6.2 0.01 15.6 1.4 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 ORY44831.1 - 0.0023 17.2 1.2 0.0089 15.3 0.5 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.10 ORY44831.1 - 0.0041 16.2 0.1 0.0044 16.1 0.1 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.6 ORY44831.1 - 0.0067 16.4 1.9 0.14 12.2 0.3 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY44831.1 - 0.02 14.6 0.5 0.19 11.5 1.4 2.2 3 0 0 3 3 3 0 TPR repeat TPR_16 PF13432.6 ORY44831.1 - 0.038 14.6 5.4 10 6.8 1.5 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 ORY44831.1 - 0.051 14.0 0.7 1.9 8.9 0.0 2.4 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_17 PF13431.6 ORY44831.1 - 0.062 13.7 0.2 13 6.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY44831.1 - 0.28 11.9 4.9 9.6 7.1 0.9 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat GMP_synt_C PF00958.22 ORY44834.1 - 1.7e-46 156.2 0.0 3.5e-46 155.2 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 ORY44834.1 - 5.2e-37 127.5 0.0 9e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORY44834.1 - 4e-09 36.6 0.2 1.2e-08 35.0 0.2 1.8 1 1 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.17 ORY44834.1 - 2.3e-08 33.5 0.1 1.7e-06 27.3 0.0 2.2 2 0 0 2 2 2 1 NAD synthase tRNA_Me_trans PF03054.16 ORY44834.1 - 0.0052 15.6 0.1 0.01 14.7 0.1 1.4 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 ORY44834.1 - 0.022 14.3 0.0 0.094 12.2 0.0 1.9 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ThiI PF02568.14 ORY44834.1 - 0.022 14.3 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 ORY44834.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Homoserine_dh PF00742.19 ORY44835.1 - 3.9e-51 173.4 0.0 6e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 ORY44835.1 - 5.9e-18 65.6 0.2 1.3e-17 64.5 0.2 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 ORY44835.1 - 0.0096 16.4 0.1 0.026 15.0 0.1 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 ORY44835.1 - 0.017 15.4 0.0 0.028 14.7 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain EF-hand_1 PF00036.32 ORY44836.1 - 2.7e-07 29.7 0.5 8.8e-05 21.8 0.0 3.6 3 1 1 4 4 4 1 EF hand EF-hand_7 PF13499.6 ORY44836.1 - 1.2e-06 28.9 0.1 0.00017 22.0 0.0 2.9 1 1 2 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 ORY44836.1 - 6.4e-06 25.7 0.1 0.0013 18.5 0.0 3.6 3 1 1 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 ORY44836.1 - 0.00042 20.1 0.9 0.0041 16.9 0.1 2.8 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 ORY44836.1 - 0.0025 18.1 0.0 0.037 14.4 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 ORY44836.1 - 0.055 13.0 0.0 0.2 11.2 0.0 2.0 2 0 0 2 2 2 0 EF hand 7tm_1 PF00001.21 ORY44837.1 - 5e-15 55.5 15.4 6.4e-15 55.2 15.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_1 PF00001.21 ORY44838.1 - 7.4e-12 45.1 6.9 9e-12 44.9 6.9 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF4131 PF13567.6 ORY44838.1 - 0.034 13.8 0.1 0.034 13.8 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) E1-E2_ATPase PF00122.20 ORY44838.1 - 4.7 6.7 7.1 1.4 8.4 1.0 2.7 2 1 1 3 3 3 0 E1-E2 ATPase HECT PF00632.25 ORY44839.1 - 2.4e-58 198.1 0.0 2.6e-58 197.9 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Zn_clus PF00172.18 ORY44841.1 - 5.9e-06 26.3 8.0 1.2e-05 25.3 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY44842.1 - 2.8e-05 23.3 0.3 6e-05 22.2 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain ERCC4 PF02732.15 ORY44843.1 - 1.7e-10 41.3 0.0 5.3e-10 39.7 0.0 1.9 1 0 0 1 1 1 1 ERCC4 domain LAP1C PF05609.12 ORY44843.1 - 0.89 8.6 28.4 1.5 7.8 28.4 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Hamartin PF04388.12 ORY44843.1 - 7.4 5.1 29.4 9.9 4.7 29.4 1.1 1 0 0 1 1 1 0 Hamartin protein Zn_clus PF00172.18 ORY44845.1 - 0.0012 18.9 10.7 0.0012 18.9 10.7 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_11 PF13086.6 ORY44846.1 - 4.9e-13 49.5 0.0 6.7e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY44846.1 - 5.9e-08 33.2 0.1 1.1e-07 32.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY44846.1 - 9.3e-07 28.8 0.0 1.3e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 ORY44846.1 - 5.3e-05 23.0 0.0 8.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.21 ORY44846.1 - 0.00097 18.7 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.14 ORY44846.1 - 0.0022 17.8 0.0 0.0038 17.1 0.0 1.3 1 0 0 1 1 1 1 Helicase AAA_16 PF13191.6 ORY44846.1 - 0.0028 18.0 0.1 0.0046 17.4 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain ResIII PF04851.15 ORY44846.1 - 0.0031 17.5 0.0 0.0046 17.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.29 ORY44846.1 - 0.013 15.9 0.0 0.024 15.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 ORY44846.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 ORY44846.1 - 0.044 13.3 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY44846.1 - 0.047 14.1 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.16 ORY44846.1 - 0.049 13.1 0.0 0.077 12.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 ORY44846.1 - 0.074 13.6 0.0 0.13 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 ORY44846.1 - 0.081 12.0 0.4 0.17 10.9 0.2 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein PIF1 PF05970.14 ORY44846.1 - 0.088 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_7 PF12775.7 ORY44846.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Polyoma_coat2 PF00761.20 ORY44846.1 - 0.15 11.7 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus coat protein DUF2075 PF09848.9 ORY44846.1 - 0.16 11.2 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF4771 PF15995.5 ORY44847.1 - 0.092 13.0 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) AAA_12 PF13087.6 ORY44848.1 - 6.8e-26 91.1 0.0 1.5e-25 90.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 ORY44848.1 - 7.4e-05 22.6 0.0 0.0052 16.5 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 ORY44848.1 - 0.022 14.3 0.1 0.61 9.5 0.0 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 ORY44848.1 - 0.026 14.9 0.2 0.35 11.2 0.2 2.3 1 1 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 ORY44848.1 - 0.12 12.2 0.1 0.28 11.1 0.1 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 ORY44849.1 - 1.1e-10 41.5 0.0 6.3e-06 25.8 0.0 3.4 2 2 1 3 3 3 2 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 ORY44849.1 - 1.5e-06 27.9 0.0 0.028 14.2 0.0 2.6 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain DUF3294 PF07957.11 ORY44850.1 - 4.5e-07 29.8 0.0 6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) Asp PF00026.23 ORY44851.1 - 2.4e-15 56.8 4.9 9.2e-15 54.9 4.9 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY44851.1 - 0.01 16.1 1.2 0.037 14.3 1.2 1.9 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY44851.1 - 0.048 13.4 0.0 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal TPR_12 PF13424.6 ORY44852.1 - 8e-14 51.7 2.5 0.002 18.4 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 ORY44852.1 - 4.7e-09 35.8 0.4 5.8e-05 22.8 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY44852.1 - 5.4e-06 26.0 0.1 0.41 10.6 0.0 4.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY44852.1 - 1.7e-05 24.6 0.0 1 9.6 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY44852.1 - 0.00072 19.4 0.2 1.5 9.1 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat ABC_tran PF00005.27 ORY44853.1 - 3.5e-53 179.8 3.8 1.2e-29 103.5 0.1 3.8 4 0 0 4 4 3 2 ABC transporter ABC_membrane PF00664.23 ORY44853.1 - 7.1e-51 173.5 28.0 1.6e-33 116.5 7.3 2.4 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ORY44853.1 - 1.2e-12 47.8 0.6 0.00031 20.2 0.0 4.7 4 1 1 5 5 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY44853.1 - 3.5e-11 43.8 0.1 9.7e-05 22.8 0.0 3.5 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 ORY44853.1 - 1e-10 41.2 2.0 0.0013 18.4 0.1 3.7 3 0 0 3 3 3 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 ORY44853.1 - 6.6e-08 32.2 0.1 0.067 12.5 0.0 3.3 3 0 0 3 3 3 3 FtsK/SpoIIIE family T2SSE PF00437.20 ORY44853.1 - 2.3e-07 30.2 0.1 0.00074 18.7 0.0 3.2 3 0 0 3 3 3 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 ORY44853.1 - 1.3e-06 28.5 0.1 0.049 13.7 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.9 ORY44853.1 - 4.9e-06 25.7 0.2 0.68 8.8 0.1 3.3 3 0 0 3 3 3 2 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 ORY44853.1 - 5.8e-06 27.0 3.2 0.0043 17.6 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_21 PF13304.6 ORY44853.1 - 1.3e-05 25.2 3.3 0.098 12.5 0.1 4.1 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 ORY44853.1 - 1.4e-05 24.7 0.5 0.17 11.4 0.0 3.4 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_30 PF13604.6 ORY44853.1 - 2.3e-05 24.2 0.4 0.44 10.2 0.0 3.6 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 ORY44853.1 - 3.5e-05 23.8 0.2 0.038 13.9 0.0 3.0 3 0 0 3 3 3 1 RsgA GTPase DUF87 PF01935.17 ORY44853.1 - 0.00011 22.4 4.2 0.025 14.7 0.1 3.0 3 0 0 3 3 3 2 Helicase HerA, central domain AAA_22 PF13401.6 ORY44853.1 - 0.00015 22.0 0.7 1.6 9.0 0.0 4.2 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.6 ORY44853.1 - 0.00036 20.2 0.3 0.019 14.5 0.0 3.4 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 ORY44853.1 - 0.00048 20.5 0.1 2.1 8.8 0.0 3.4 3 0 0 3 3 3 1 RNA helicase IstB_IS21 PF01695.17 ORY44853.1 - 0.00078 19.2 0.0 0.16 11.7 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein Dynamin_N PF00350.23 ORY44853.1 - 0.0017 18.5 2.8 0.14 12.2 0.5 3.0 3 0 0 3 3 2 1 Dynamin family Sigma54_activat PF00158.26 ORY44853.1 - 0.0029 17.4 0.1 1.1 8.9 0.0 3.1 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_15 PF13175.6 ORY44853.1 - 0.0031 17.3 0.4 0.23 11.1 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 ORY44853.1 - 0.0041 16.4 0.4 0.14 11.4 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin ATP-synt_ab PF00006.25 ORY44853.1 - 0.0042 16.8 0.9 5.1 6.7 0.1 3.4 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 ORY44853.1 - 0.0048 16.8 1.8 0.68 9.8 0.0 3.5 3 1 0 3 3 3 1 NACHT domain DUF815 PF05673.13 ORY44853.1 - 0.0067 15.6 0.6 4.7 6.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 ORY44853.1 - 0.0088 15.8 0.5 10 5.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain Pox_A32 PF04665.12 ORY44853.1 - 0.009 15.5 0.6 25 4.2 0.0 3.5 3 0 0 3 3 3 0 Poxvirus A32 protein AAA PF00004.29 ORY44853.1 - 0.0095 16.4 0.6 1.3 9.5 0.0 3.5 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 ORY44853.1 - 0.012 15.4 5.0 2.5 7.9 0.1 4.0 4 1 0 4 4 3 0 DEAD/DEAH box helicase AAA_33 PF13671.6 ORY44853.1 - 0.015 15.4 0.1 0.85 9.8 0.1 2.7 3 0 0 3 3 2 0 AAA domain AAA_10 PF12846.7 ORY44853.1 - 0.017 14.1 0.5 2.2 7.1 0.0 3.0 3 0 0 3 3 3 0 AAA-like domain ATP_bind_1 PF03029.17 ORY44853.1 - 0.019 14.8 0.8 2.9 7.6 0.2 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PhoH PF02562.16 ORY44853.1 - 0.024 14.1 0.2 0.41 10.1 0.0 2.6 3 0 0 3 3 2 0 PhoH-like protein IIGP PF05049.13 ORY44853.1 - 0.026 13.6 0.5 2.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Roc PF08477.13 ORY44853.1 - 0.031 14.5 0.7 18 5.5 0.0 3.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_19 PF13245.6 ORY44853.1 - 0.052 13.9 1.4 36 4.7 0.0 3.9 3 1 0 3 3 3 0 AAA domain AAA_14 PF13173.6 ORY44853.1 - 0.064 13.3 0.2 61 3.7 0.0 3.8 3 1 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 ORY44853.1 - 0.065 12.6 0.2 28 4.0 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ORY44853.1 - 0.068 13.2 0.7 6.6 6.7 0.0 3.4 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ORY44853.1 - 0.073 13.6 0.4 1.7 9.2 0.1 2.8 2 1 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 ORY44853.1 - 0.09 12.7 0.1 7.6 6.4 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 SRP54 PF00448.22 ORY44853.1 - 0.092 12.4 0.3 2.4 7.7 0.0 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 ORY44853.1 - 0.12 12.2 0.4 6.8 6.5 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea DNA_pol_alpha_N PF12254.8 ORY44853.1 - 0.16 12.1 0.0 0.49 10.5 0.0 1.8 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Gtr1_RagA PF04670.12 ORY44853.1 - 0.21 10.9 2.5 1.3 8.3 0.1 2.8 3 0 0 3 3 2 0 Gtr1/RagA G protein conserved region RRM_1 PF00076.22 ORY44854.1 - 0.00089 19.0 0.0 0.046 13.5 0.0 2.6 1 1 2 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_12 PF13424.6 ORY44855.1 - 7.8e-12 45.3 5.9 0.00034 20.8 0.2 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 ORY44855.1 - 6e-05 22.8 0.5 0.011 15.6 0.1 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY44855.1 - 0.00016 21.4 1.7 0.28 11.1 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY44855.1 - 0.0024 17.8 6.1 0.63 10.2 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY44855.1 - 0.027 14.6 0.1 6.2 7.3 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Hamartin PF04388.12 ORY44855.1 - 1.9 7.1 12.1 2.9 6.5 12.1 1.2 1 0 0 1 1 1 0 Hamartin protein RhoGEF PF00621.20 ORY44857.1 - 2.8e-42 145.0 0.1 4.4e-42 144.4 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain LRR_8 PF13855.6 ORY44857.1 - 1.7e-13 50.1 13.7 6.5e-07 29.0 1.0 3.5 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY44857.1 - 4.7e-13 49.1 9.4 0.00017 21.9 1.7 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORY44857.1 - 0.035 13.6 1.5 1.2 8.6 0.2 2.3 1 1 1 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.33 ORY44857.1 - 0.066 13.8 14.8 6.3 7.8 0.3 5.4 4 0 0 4 4 4 0 Leucine Rich Repeat NTR2 PF15458.6 ORY44857.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Nineteen complex-related protein 2 LRR_6 PF13516.6 ORY44857.1 - 0.81 9.9 12.8 38 4.7 0.3 4.8 4 0 0 4 4 4 0 Leucine Rich repeat zf-C3HC4 PF00097.25 ORY44858.1 - 1.8e-09 37.3 6.0 1.8e-09 37.3 6.0 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY44858.1 - 7.4e-09 35.5 3.2 2.3e-08 33.9 3.2 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORY44858.1 - 1.3e-08 34.6 6.7 1.3e-08 34.6 6.7 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY44858.1 - 3.8e-08 33.5 8.6 3.8e-08 33.5 8.6 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY44858.1 - 6.9e-07 29.0 6.3 6.9e-07 29.0 6.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY44858.1 - 9.9e-06 25.4 6.7 9.9e-06 25.4 6.7 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORY44858.1 - 1.5e-05 25.0 7.3 1.5e-05 25.0 7.3 1.9 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ORY44858.1 - 0.00075 19.3 6.7 0.00075 19.3 6.7 2.2 2 0 0 2 2 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 ORY44858.1 - 0.00076 19.3 3.2 0.00076 19.3 3.2 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 ORY44858.1 - 0.0041 17.4 7.3 0.0041 17.4 7.3 3.0 2 1 1 3 3 3 1 RING-H2 zinc finger domain DZR PF12773.7 ORY44858.1 - 0.0049 16.9 7.6 0.088 12.9 2.6 2.5 1 1 1 2 2 2 1 Double zinc ribbon zf-RING_10 PF16685.5 ORY44858.1 - 0.0061 16.7 4.7 0.0061 16.7 4.7 1.9 2 1 0 2 2 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 ORY44858.1 - 0.0095 15.8 3.6 0.0095 15.8 3.6 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein DUF2685 PF10886.8 ORY44858.1 - 0.028 14.6 1.3 0.84 9.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2685) zf-RING_11 PF17123.5 ORY44858.1 - 0.03 14.1 6.9 0.076 12.8 3.9 2.5 2 0 0 2 2 2 0 RING-like zinc finger CCSMST1 PF15013.6 ORY44858.1 - 0.055 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 CCSMST1 family DUF5129 PF17173.4 ORY44858.1 - 0.18 10.9 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5129) zf-ANAPC11 PF12861.7 ORY44858.1 - 1.6 8.8 12.0 0.059 13.4 3.2 2.7 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2673 PF10880.8 ORY44860.1 - 0.0076 16.4 0.1 0.012 15.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2673) Pkinase PF00069.25 ORY44861.1 - 7.5e-44 150.1 0.0 3.1e-43 148.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY44861.1 - 5e-26 91.5 0.0 3.1e-25 88.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase GPI-anchored PF10342.9 ORY44862.1 - 1.2e-05 25.9 4.6 1.8e-05 25.4 4.6 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Big_10 PF17964.1 ORY44862.1 - 0.0011 19.0 0.8 0.67 9.9 0.1 2.1 2 0 0 2 2 2 2 Bacterial Ig domain DUF5525 PF17663.1 ORY44862.1 - 0.0089 14.2 7.5 0.0099 14.0 7.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5525) Pirin PF02678.16 ORY44863.1 - 3.5e-06 27.0 0.1 1.1e-05 25.4 0.1 1.7 1 1 0 1 1 1 1 Pirin AAA_29 PF13555.6 ORY44863.1 - 0.15 11.8 0.0 0.42 10.4 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain GPI-anchored PF10342.9 ORY44864.1 - 0.00059 20.5 0.1 0.0015 19.2 0.1 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Prenylcys_lyase PF07156.14 ORY44865.1 - 6.2e-48 163.7 0.1 2.4e-25 89.4 0.1 2.1 1 1 1 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.6 ORY44865.1 - 2.6e-11 43.6 0.0 5.8e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 ORY44865.1 - 2.6e-06 27.0 0.0 3.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 ORY44865.1 - 0.0007 18.9 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY44865.1 - 0.0022 17.7 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORY44865.1 - 0.016 15.2 0.1 0.034 14.1 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 ORY44865.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain PriCT_1 PF08708.11 ORY44866.1 - 0.003 17.2 0.0 0.0066 16.2 0.0 1.6 1 0 0 1 1 1 1 Primase C terminal 1 (PriCT-1) PX PF00787.24 ORY44867.1 - 0.017 15.1 0.0 0.032 14.2 0.0 1.5 1 0 0 1 1 1 0 PX domain Beta-lactamase PF00144.24 ORY44868.1 - 2.7e-34 118.9 0.0 3.9e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 ORY44868.1 - 0.08 12.5 0.0 0.25 10.9 0.0 1.7 2 0 0 2 2 2 0 Beta-lactamase enzyme family Zn_clus PF00172.18 ORY44869.1 - 1.4e-05 25.1 9.9 3e-05 24.1 9.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY44869.1 - 0.0051 15.9 0.1 0.01 14.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 ORY44870.1 - 0.00051 19.2 0.0 0.001 18.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY44871.1 - 5.8e-06 26.3 9.7 8.9e-06 25.7 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BNIP3 PF06553.12 ORY44871.1 - 0.024 14.3 0.3 0.035 13.8 0.3 1.2 1 0 0 1 1 1 0 BNIP3 MGC-24 PF05283.11 ORY44872.1 - 0.17 12.3 1.3 0.25 11.8 1.3 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Zn_clus PF00172.18 ORY44872.1 - 0.59 10.3 10.6 0.85 9.8 10.6 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.7 ORY44873.1 - 3.8e-05 24.4 2.7 7.5e-05 23.4 2.7 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 ORY44873.1 - 5.6e-05 23.0 1.3 6.9e-05 22.7 0.3 1.8 2 1 0 2 2 2 1 PGAP1-like protein Thioesterase PF00975.20 ORY44873.1 - 0.00013 22.1 0.8 0.00026 21.2 0.7 1.7 1 1 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 ORY44873.1 - 0.00015 21.1 0.1 0.00024 20.5 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 ORY44873.1 - 0.0004 20.0 0.1 0.00056 19.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) LCAT PF02450.15 ORY44873.1 - 0.0006 19.1 0.2 0.00081 18.7 0.2 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 ORY44873.1 - 0.00092 18.8 0.4 0.0024 17.5 0.5 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) LIDHydrolase PF10230.9 ORY44873.1 - 0.01 15.4 0.2 0.048 13.2 0.2 1.9 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Esterase PF00756.20 ORY44873.1 - 0.025 14.2 0.0 0.053 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 ORY44873.1 - 0.06 13.0 0.3 0.28 10.8 0.2 2.0 2 1 0 2 2 2 0 alpha/beta hydrolase fold MCLC PF05934.11 ORY44873.1 - 0.48 9.1 4.0 0.74 8.5 4.0 1.3 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF4698 PF15769.5 ORY44875.1 - 0.21 10.6 0.7 0.36 9.8 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Thioredoxin_6 PF13848.6 ORY44877.1 - 4.3e-08 33.3 0.0 1.2e-07 31.8 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Pkinase PF00069.25 ORY44878.1 - 5.3e-53 180.1 0.0 4.3e-39 134.5 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY44878.1 - 1.7e-26 93.0 0.0 4.7e-26 91.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY44878.1 - 0.0005 19.5 0.1 0.00092 18.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY44878.1 - 0.0014 18.6 0.0 0.0038 17.2 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY44878.1 - 0.0033 16.8 0.0 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY44878.1 - 0.0052 15.8 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 ORY44878.1 - 0.049 13.2 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 RIO1 family YbjQ_1 PF01906.17 ORY44879.1 - 0.097 13.3 0.5 0.22 12.2 0.2 1.7 2 0 0 2 2 2 0 Putative heavy-metal-binding SAM_PNT PF02198.16 ORY44881.1 - 0.011 15.7 0.1 0.05 13.6 0.1 2.0 1 1 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF3430 PF11912.8 ORY44881.1 - 0.55 10.3 21.3 0.24 11.4 0.2 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3430) Adaptin_N PF01602.20 ORY44882.1 - 6.5e-104 348.4 4.9 1e-103 347.7 4.9 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 ORY44882.1 - 1.5e-61 206.0 0.1 4.5e-61 204.5 0.1 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 ORY44882.1 - 6.1e-60 201.2 1.5 2.2e-59 199.3 0.4 2.5 3 0 0 3 3 3 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 ORY44882.1 - 1.7e-10 41.1 0.0 0.0057 17.0 0.0 4.1 1 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 ORY44882.1 - 1.4e-08 35.0 5.0 3.1e-06 27.3 0.1 3.2 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORY44882.1 - 1.5e-06 28.0 0.1 0.75 10.2 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat Coatomer_g_Cpla PF16381.5 ORY44882.1 - 0.00016 21.8 0.0 0.00052 20.1 0.0 2.0 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform PAPA-1 PF04795.12 ORY44882.1 - 0.076 13.8 0.9 0.72 10.7 0.2 2.5 2 0 0 2 2 2 0 PAPA-1-like conserved region DUF2664 PF10867.8 ORY44882.1 - 0.096 13.1 0.4 24 5.5 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2664) Arm PF00514.23 ORY44882.1 - 0.097 12.8 0.0 13 6.0 0.0 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat TPR_2 PF07719.17 ORY44883.1 - 1.8e-06 27.6 11.1 0.00026 20.9 0.5 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY44883.1 - 2.6e-06 27.0 1.6 2.2e-05 24.0 1.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY44883.1 - 3e-05 23.9 4.2 0.0044 17.1 0.5 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY44883.1 - 0.00013 22.2 1.7 0.2 12.0 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY44883.1 - 0.016 15.7 0.5 1.7 9.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat NARP1 PF12569.8 ORY44883.1 - 0.016 14.1 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Vac_Fusion PF02346.16 ORY44883.1 - 0.042 13.5 0.1 0.23 11.1 0.5 2.0 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 TPR_7 PF13176.6 ORY44883.1 - 0.063 13.3 1.4 0.19 11.8 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY44883.1 - 0.092 12.8 3.4 3.3 7.9 0.5 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 ORY44883.1 - 0.37 10.7 8.8 42 4.2 0.5 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY44883.1 - 0.6 10.9 6.5 24 5.8 0.5 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat 60KD_IMP PF02096.20 ORY44885.1 - 0.014 15.3 2.2 0.027 14.4 2.2 1.5 1 0 0 1 1 1 0 60Kd inner membrane protein DUF2583 PF10762.9 ORY44885.1 - 0.29 11.6 1.9 0.43 11.0 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) ABC_membrane PF00664.23 ORY44886.1 - 1.4e-142 474.2 62.9 1.3e-41 143.1 8.3 4.1 4 0 0 4 4 4 4 ABC transporter transmembrane region ABC_tran PF00005.27 ORY44886.1 - 1.5e-118 391.5 1.1 7.3e-33 114.0 0.0 4.5 4 0 0 4 4 4 4 ABC transporter SMC_N PF02463.19 ORY44886.1 - 2.8e-20 72.7 17.5 0.012 15.0 0.0 8.3 5 3 1 6 6 6 6 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY44886.1 - 2.8e-15 56.4 9.8 0.0082 16.2 0.2 4.9 4 0 0 4 4 4 4 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY44886.1 - 2.6e-14 52.7 6.4 0.048 13.4 0.2 4.5 4 0 0 4 4 4 4 P-loop containing region of AAA domain AAA_23 PF13476.6 ORY44886.1 - 1.2e-12 48.7 3.3 0.21 12.1 0.0 5.3 5 0 0 5 5 5 3 AAA domain RsgA_GTPase PF03193.16 ORY44886.1 - 6.4e-12 45.7 9.0 0.0019 18.1 0.1 4.5 4 0 0 4 4 4 2 RsgA GTPase AAA_16 PF13191.6 ORY44886.1 - 9.4e-12 45.6 0.6 0.2 12.0 0.0 4.8 5 0 0 5 5 4 3 AAA ATPase domain DUF87 PF01935.17 ORY44886.1 - 4.6e-10 40.0 13.5 0.0064 16.6 0.1 4.7 4 0 0 4 4 4 4 Helicase HerA, central domain AAA_21 PF13304.6 ORY44886.1 - 9.1e-10 38.8 9.3 0.091 12.6 0.0 5.1 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 ORY44886.1 - 1.9e-09 37.1 7.4 0.031 13.5 0.1 4.3 4 0 0 4 4 4 2 Zeta toxin AAA_30 PF13604.6 ORY44886.1 - 9e-09 35.3 3.2 2.1 8.0 0.0 4.8 4 0 0 4 4 4 4 AAA domain AAA_15 PF13175.6 ORY44886.1 - 2.1e-08 34.3 8.4 0.16 11.7 0.0 5.1 5 0 0 5 5 5 2 AAA ATPase domain Dynamin_N PF00350.23 ORY44886.1 - 4.4e-08 33.4 24.9 0.0064 16.6 2.0 5.1 5 0 0 5 5 4 3 Dynamin family T2SSE PF00437.20 ORY44886.1 - 6.9e-08 31.9 1.5 0.39 9.7 0.0 4.3 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_7 PF12775.7 ORY44886.1 - 1.3e-07 31.4 4.4 2.1 7.8 0.0 4.3 4 0 0 4 4 4 3 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 ORY44886.1 - 1.6e-07 30.6 5.2 0.71 8.7 0.1 4.2 4 0 0 4 4 4 3 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 ORY44886.1 - 2.4e-07 30.8 4.7 0.68 9.8 0.1 4.4 4 0 0 4 4 4 2 NACHT domain cobW PF02492.19 ORY44886.1 - 3.1e-07 30.2 8.2 0.029 14.0 0.1 4.3 4 0 0 4 4 4 2 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 ORY44886.1 - 5e-07 30.1 3.6 3.5 7.9 0.0 4.9 4 1 0 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.18 ORY44886.1 - 1.4e-06 27.9 3.7 4.2 6.7 0.0 4.4 4 0 0 4 4 4 0 FtsK/SpoIIIE family DUF815 PF05673.13 ORY44886.1 - 1.6e-06 27.5 4.3 1.8 7.7 0.0 4.6 4 0 0 4 4 4 1 Protein of unknown function (DUF815) NB-ARC PF00931.22 ORY44886.1 - 4.8e-06 25.9 7.8 2.7 7.1 0.1 4.4 4 0 0 4 4 4 3 NB-ARC domain ATPase_2 PF01637.18 ORY44886.1 - 1.5e-05 25.1 1.2 1.1 9.1 0.0 4.4 4 0 0 4 4 4 2 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 ORY44886.1 - 1.7e-05 24.3 2.7 0.38 9.9 0.3 4.5 5 1 0 5 5 5 2 KAP family P-loop domain Roc PF08477.13 ORY44886.1 - 3.5e-05 24.0 7.1 10 6.3 0.1 4.8 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 ORY44886.1 - 0.0001 22.7 3.2 12 6.3 0.0 4.7 4 0 0 4 4 4 0 RNA helicase Sigma54_activat PF00158.26 ORY44886.1 - 0.00013 21.8 0.9 17 5.0 0.0 4.3 4 0 0 4 4 4 0 Sigma-54 interaction domain AAA PF00004.29 ORY44886.1 - 0.001 19.5 2.3 56 4.2 0.1 5.2 4 2 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) IIGP PF05049.13 ORY44886.1 - 0.0012 17.9 3.6 9.7 5.1 0.0 4.1 4 0 0 4 4 4 0 Interferon-inducible GTPase (IIGP) AAA_PrkA PF08298.11 ORY44886.1 - 0.0015 17.5 1.1 26 3.6 0.1 4.1 4 0 0 4 4 4 0 PrkA AAA domain ATP-synt_ab PF00006.25 ORY44886.1 - 0.0022 17.7 0.4 43 3.7 0.0 4.1 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.9 ORY44886.1 - 0.0036 17.0 5.5 9.2 6.0 0.1 4.4 4 0 0 4 4 4 0 Ethanolamine utilisation - propanediol utilisation ABC_ATPase PF09818.9 ORY44886.1 - 0.0044 15.9 0.4 5.4 5.7 0.0 3.8 5 0 0 5 5 5 0 Predicted ATPase of the ABC class MeaB PF03308.16 ORY44886.1 - 0.0052 15.8 11.6 1.8 7.5 0.1 4.5 5 0 0 5 5 4 1 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 ORY44886.1 - 0.0066 16.2 6.4 22 4.7 0.0 5.4 6 0 0 6 6 4 0 IstB-like ATP binding protein TsaE PF02367.17 ORY44886.1 - 0.0093 16.0 1.9 28 4.7 0.0 4.2 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RecA PF00154.21 ORY44886.1 - 0.0093 15.5 0.0 3.6 7.0 0.0 2.3 2 0 0 2 2 2 0 recA bacterial DNA recombination protein Ploopntkinase3 PF18751.1 ORY44886.1 - 0.011 15.6 4.4 23 4.8 0.0 4.4 4 0 0 4 4 4 0 P-loop Nucleotide Kinase3 GTP_EFTU PF00009.27 ORY44886.1 - 0.011 15.2 0.4 33 3.9 0.0 4.0 4 0 0 4 4 4 0 Elongation factor Tu GTP binding domain Adeno_IVa2 PF02456.15 ORY44886.1 - 0.015 14.1 2.5 4.2 6.1 0.0 4.0 4 0 0 4 4 4 0 Adenovirus IVa2 protein PIF1 PF05970.14 ORY44886.1 - 0.018 14.2 2.0 12 4.9 0.0 3.6 4 0 0 4 4 4 0 PIF1-like helicase AAA_25 PF13481.6 ORY44886.1 - 0.021 14.4 0.1 13 5.3 0.0 3.4 4 0 0 4 4 4 0 AAA domain FeoB_N PF02421.18 ORY44886.1 - 0.024 14.1 4.6 10 5.6 0.2 4.0 4 0 0 4 4 4 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 ORY44886.1 - 0.025 14.3 14.0 2.2 8.0 0.1 4.3 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_35 PF14516.6 ORY44886.1 - 0.027 13.3 0.5 5.1 5.8 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain MobB PF03205.14 ORY44886.1 - 0.047 13.6 7.6 19 5.2 0.1 4.4 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.6 ORY44886.1 - 0.098 13.0 3.2 15 5.9 0.0 3.5 4 0 0 4 4 2 0 AAA domain AAA_24 PF13479.6 ORY44886.1 - 0.18 11.5 5.3 12 5.6 0.0 4.0 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.6 ORY44886.1 - 0.41 11.2 16.2 9.3 6.8 0.1 5.4 6 0 0 6 6 4 0 AAA domain CDC45 PF02724.14 ORY44886.1 - 0.87 7.8 4.6 1.1 7.4 0.5 2.1 2 0 0 2 2 2 0 CDC45-like protein AIG1 PF04548.16 ORY44886.1 - 1.4 8.2 19.8 1.8 7.9 0.3 5.1 5 0 0 5 5 5 0 AIG1 family AAA_10 PF12846.7 ORY44886.1 - 1.8 7.4 9.5 31 3.3 0.3 4.0 4 0 0 4 4 4 0 AAA-like domain NTPase_1 PF03266.15 ORY44886.1 - 2.2 8.2 12.0 15 5.4 0.2 4.5 4 0 0 4 4 4 0 NTPase AAA_5 PF07728.14 ORY44886.1 - 2.3 8.2 7.6 64 3.5 0.0 4.9 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 ORY44886.1 - 3 8.0 9.4 1.2e+02 2.8 0.2 4.5 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.6 ORY44886.1 - 3.2 8.0 8.7 86 3.3 0.1 4.5 4 0 0 4 4 4 0 AAA domain DUF4484 PF14831.6 ORY44886.1 - 4.2 7.4 6.3 0.41 10.6 0.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) PRK PF00485.18 ORY44886.1 - 5.9 6.6 10.9 18 5.0 0.1 4.3 4 0 0 4 4 4 0 Phosphoribulokinase / Uridine kinase family Mem_trans PF03547.18 ORY44887.1 - 5.8e-22 77.6 17.5 4.3e-21 74.8 17.5 1.9 1 1 0 1 1 1 1 Membrane transport protein Acyl-CoA_dh_1 PF00441.24 ORY44888.1 - 6.1e-49 166.1 1.8 8.4e-49 165.6 1.8 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY44888.1 - 2e-27 96.1 0.0 5.8e-27 94.6 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ORY44888.1 - 7.4e-25 87.0 0.0 1.4e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY44888.1 - 1.5e-22 80.3 0.9 2.1e-22 79.9 0.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cupin_8 PF13621.6 ORY44889.1 - 1.7e-35 123.0 0.0 2.7e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 ORY44889.1 - 3.6e-08 33.2 0.1 7.6e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 ORY44889.1 - 0.017 14.8 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 Cupin domain PCO_ADO PF07847.12 ORY44889.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 PCO_ADO Zn_clus PF00172.18 ORY44890.1 - 0.005 16.9 11.1 0.011 15.8 11.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gin PF10764.9 ORY44890.1 - 0.46 10.5 5.3 1.1 9.3 5.3 1.6 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin Redoxin PF08534.10 ORY44891.1 - 9.7e-35 119.4 0.2 1.1e-34 119.3 0.2 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 ORY44891.1 - 4.4e-11 42.8 0.0 4.6e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family BPL_LplA_LipB PF03099.19 ORY44892.1 - 4.1e-10 39.7 0.0 2e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF2207 PF09972.9 ORY44893.1 - 0.054 12.3 0.5 0.08 11.7 0.2 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) MbeB_N PF04837.12 ORY44893.1 - 0.12 12.7 0.1 0.19 12.1 0.1 1.3 1 0 0 1 1 1 0 MbeB-like, N-term conserved region ATP-synt_Z PF16594.5 ORY44893.1 - 0.23 11.0 2.1 0.36 10.3 0.2 2.3 2 0 0 2 2 2 0 Putative AtpZ or ATP-synthase-associated PEP-CTERM PF07589.11 ORY44893.1 - 9.6 6.5 5.9 60 3.9 0.3 2.9 2 1 0 2 2 2 0 PEP-CTERM motif CLP1_P PF16575.5 ORY44894.1 - 5e-36 124.3 0.0 8.2e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop CLP1_N PF16573.5 ORY44894.1 - 3.4e-25 88.1 0.0 6.1e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Clp1 PF06807.14 ORY44894.1 - 1.5e-10 41.5 0.0 3e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 IstB_IS21 PF01695.17 ORY44894.1 - 0.012 15.4 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 ORY44894.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.6 ORY44894.1 - 0.02 15.3 0.0 0.046 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 ORY44894.1 - 0.077 13.4 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 ORY44894.1 - 0.077 12.7 0.0 5.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 ORY44894.1 - 0.12 12.9 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 ORY44894.1 - 0.12 12.4 0.0 0.32 11.1 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Roc PF08477.13 ORY44894.1 - 0.18 12.0 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PHD PF00628.29 ORY44895.1 - 5.2e-07 29.5 4.1 9e-07 28.7 4.1 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORY44895.1 - 0.00054 19.4 2.0 0.0011 18.5 2.0 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 ORY44895.1 - 0.0022 17.9 1.7 0.0051 16.7 1.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.6 ORY44895.1 - 0.013 15.7 0.2 0.033 14.4 0.2 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain C1_1 PF00130.22 ORY44895.1 - 0.019 14.9 0.5 0.044 13.7 0.5 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.6 ORY44895.1 - 0.052 13.7 0.5 0.11 12.7 0.5 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain DUF1677 PF07911.13 ORY44895.1 - 0.076 13.4 3.1 0.48 10.8 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1677) C1_2 PF03107.16 ORY44895.1 - 0.13 12.6 4.1 0.071 13.4 1.7 1.8 2 0 0 2 2 2 0 C1 domain zf-rbx1 PF12678.7 ORY44895.1 - 0.38 11.1 5.7 0.79 10.1 0.4 2.7 2 0 0 2 2 2 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 ORY44895.1 - 2.1 8.0 7.1 0.23 11.1 2.5 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 ORY44895.1 - 3.5 8.0 12.8 3.6 8.0 0.3 2.4 2 0 0 2 2 2 0 Ring finger domain FYVE_2 PF02318.16 ORY44895.1 - 9.1 6.5 11.7 0.057 13.6 1.2 2.5 3 0 0 3 3 3 0 FYVE-type zinc finger DUF3176 PF11374.8 ORY44899.1 - 0.0067 16.6 7.0 0.023 14.9 5.1 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3176) Glyco_hydro_61 PF03443.14 ORY44901.1 - 0.0065 16.4 0.0 0.46 10.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 61 DUF1640 PF07798.11 ORY44902.1 - 1.8e-31 109.5 5.7 2.1e-31 109.3 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DSPc PF00782.20 ORY44904.1 - 0.00076 19.3 0.0 0.00086 19.1 0.0 1.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY44904.1 - 0.0014 18.3 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Acetyltransf_1 PF00583.25 ORY44906.1 - 5.7e-16 58.8 0.0 7.8e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY44906.1 - 1.6e-08 34.9 0.0 2.4e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY44906.1 - 3.4e-06 27.0 0.0 4.7e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY44906.1 - 0.0013 18.7 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 ORY44906.1 - 0.0077 16.3 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase IMPDH PF00478.25 ORY44907.1 - 6.1e-133 443.1 4.7 7.1e-133 442.9 4.7 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 ORY44907.1 - 4.1e-12 46.4 0.9 1.4e-05 25.4 0.0 3.2 4 0 0 4 4 3 2 CBS domain NMO PF03060.15 ORY44907.1 - 8.1e-12 45.2 3.9 6.1e-08 32.4 5.1 2.5 2 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 ORY44907.1 - 1.2e-10 41.0 2.3 2.5e-10 39.9 0.9 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 ORY44907.1 - 4.1e-07 29.7 3.2 1e-05 25.1 2.5 2.5 2 1 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.21 ORY44907.1 - 3e-05 23.3 1.0 0.0038 16.4 0.0 3.0 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase NanE PF04131.14 ORY44907.1 - 0.0002 20.6 0.1 0.0014 17.9 0.3 2.2 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase Dus PF01207.17 ORY44907.1 - 0.00074 18.7 0.3 0.45 9.6 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) Aldolase PF01081.19 ORY44907.1 - 0.00089 18.7 1.5 0.0015 18.0 0.3 2.0 2 0 0 2 2 2 1 KDPG and KHG aldolase ThiG PF05690.14 ORY44907.1 - 0.0022 17.3 3.1 0.0045 16.3 2.3 1.8 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG DUF561 PF04481.12 ORY44907.1 - 0.005 16.0 0.5 0.16 11.1 0.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF561) B12-binding PF02310.19 ORY44907.1 - 0.052 13.6 0.1 0.21 11.6 0.1 2.0 2 0 0 2 2 2 0 B12 binding domain G3P_antiterm PF04309.12 ORY44907.1 - 0.077 12.4 0.9 6.7 6.1 0.2 2.5 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator DHO_dh PF01180.21 ORY44907.1 - 0.35 10.0 3.3 8.3 5.5 0.5 2.5 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Arrestin_C PF02752.22 ORY44909.1 - 1.1e-15 58.2 0.3 1.2e-13 51.7 0.1 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY44909.1 - 5.5e-08 33.0 0.0 2.8e-07 30.7 0.0 2.2 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Epimerase PF01370.21 ORY44912.1 - 1.3e-26 93.5 0.1 1.7e-26 93.2 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY44912.1 - 3.3e-15 56.3 0.1 4.5e-15 55.9 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 ORY44912.1 - 6e-09 36.0 0.6 1e-08 35.3 0.6 1.5 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ORY44912.1 - 8.1e-09 35.0 0.3 1.2e-08 34.4 0.3 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 ORY44912.1 - 8.4e-09 34.8 0.1 2.6e-08 33.2 0.1 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORY44912.1 - 8.3e-05 21.9 1.1 0.00033 19.9 1.1 2.0 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 ORY44912.1 - 0.0092 15.1 0.1 0.017 14.3 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein PS-DH PF14765.6 ORY44912.1 - 0.032 13.5 0.1 0.055 12.7 0.1 1.3 1 0 0 1 1 1 0 Polyketide synthase dehydratase Aldedh PF00171.22 ORY44913.1 - 2.9e-175 583.2 0.8 3.3e-175 583.0 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ORY44913.1 - 0.015 14.3 0.7 0.088 11.8 0.7 2.0 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Peptidase_M28 PF04389.17 ORY44914.1 - 5e-34 117.7 0.0 6.3e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ORY44914.1 - 1.9e-10 40.8 0.1 8.5e-10 38.7 0.1 1.9 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 ORY44915.1 - 7.7e-30 104.1 0.1 1.1e-29 103.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ORY44915.1 - 1.8e-08 34.4 0.1 3.2e-07 30.3 0.2 2.4 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 ORY44916.1 - 4.5e-31 108.1 0.0 8.6e-31 107.2 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 ORY44916.1 - 2e-08 34.2 0.1 7e-08 32.4 0.2 1.8 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 ORY44916.1 - 0.003 17.1 0.4 0.017 14.6 0.0 2.3 3 0 0 3 3 3 1 Nicastrin CRAL_TRIO PF00650.20 ORY44917.1 - 1.8e-25 89.5 0.0 2.5e-25 89.0 0.0 1.3 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 ORY44917.1 - 2.9e-05 24.3 0.0 5.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORY44917.1 - 4.1e-05 23.7 0.0 8.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Peptidase_M28 PF04389.17 ORY44918.1 - 9e-28 97.3 0.0 2.5e-27 95.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 ORY44918.1 - 3.2e-10 40.1 0.0 6.9e-10 39.0 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 ORY44918.1 - 0.11 11.5 0.1 0.46 9.4 0.0 1.8 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Metallophos PF00149.28 ORY44919.1 - 4e-32 112.4 0.2 5e-32 112.1 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORY44919.1 - 0.029 14.8 0.1 0.074 13.5 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 ORY44919.1 - 0.049 13.8 0.0 0.071 13.3 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain A_thal_3526 PF09713.10 ORY44920.1 - 0.09 13.0 0.2 0.41 10.9 0.0 2.2 2 0 0 2 2 2 0 Plant protein 1589 of unknown function (A_thal_3526) Zn_clus PF00172.18 ORY44921.1 - 4.4e-06 26.7 7.8 8.4e-06 25.8 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY44921.1 - 0.022 13.8 0.9 0.036 13.1 0.2 1.7 2 0 0 2 2 2 0 Fungal specific transcription factor domain FPN1 PF06963.12 ORY44922.1 - 6.1e-105 351.3 20.0 7.7e-105 351.0 20.0 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Peptidase_M28 PF04389.17 ORY44923.1 - 1.1e-13 51.4 0.0 2.5e-13 50.2 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 zf-MIZ PF02891.20 ORY44925.1 - 4.5e-08 32.7 0.3 9.2e-08 31.7 0.3 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 ORY44925.1 - 3.5e-06 26.7 0.0 8.2e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit GET2 PF08690.10 ORY44925.1 - 0.045 13.4 0.7 0.083 12.6 0.7 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 HECW_N PF16562.5 ORY44925.1 - 0.095 12.5 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 zf-MIZ PF02891.20 ORY44926.1 - 2.6e-17 62.3 4.0 9.3e-17 60.5 0.9 2.4 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 ORY44926.1 - 5.2e-07 29.4 1.2 8.4e-07 28.7 0.2 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit C1_1 PF00130.22 ORY44926.1 - 0.88 9.5 6.1 5.4 7.0 1.4 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-MIZ PF02891.20 ORY44928.1 - 3.5e-15 55.5 1.7 3.5e-15 55.5 1.7 2.5 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 ORY44928.1 - 1.6e-06 27.8 0.9 1.6e-06 27.8 0.9 2.5 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit DcuA_DcuB PF03605.14 ORY44928.1 - 0.064 12.1 0.0 0.097 11.5 0.0 1.2 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter zinc_ribbon_12 PF11331.8 ORY44928.1 - 1.7 8.5 9.4 2.9 7.7 7.8 2.2 2 0 0 2 2 2 0 Probable zinc-ribbon domain PALP PF00291.25 ORY44930.1 - 4.5e-71 239.7 0.6 5.2e-71 239.4 0.6 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glutaredoxin PF00462.24 ORY44931.1 - 8.6e-17 61.1 0.1 1.4e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 ORY44931.1 - 0.00037 20.8 0.0 0.00061 20.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY44931.1 - 0.063 13.6 0.0 0.089 13.1 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain LRR_8 PF13855.6 ORY44932.1 - 1.1e-08 34.7 14.6 0.0013 18.5 0.2 4.0 3 1 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 ORY44932.1 - 2e-06 27.6 16.2 0.56 11.0 0.1 6.7 6 2 1 7 7 7 3 Leucine Rich Repeat LRR_4 PF12799.7 ORY44932.1 - 3.5e-06 27.3 20.6 0.0014 19.0 1.4 4.6 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) F-box PF00646.33 ORY44932.1 - 0.0053 16.6 0.0 0.018 14.9 0.0 2.0 1 0 0 1 1 1 1 F-box domain BshC PF10079.9 ORY44932.1 - 0.048 12.4 0.1 0.066 12.0 0.1 1.1 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC PRANC PF09372.10 ORY44932.1 - 0.11 12.8 0.8 0.3 11.4 0.2 2.0 2 0 0 2 2 2 0 PRANC domain BTB PF00651.31 ORY44933.1 - 1.3e-18 67.2 0.1 4.1e-13 49.5 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain DUF4644 PF15486.6 ORY44933.1 - 0.28 10.9 3.5 0.68 9.7 3.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4644) ECH_2 PF16113.5 ORY44934.1 - 2.9e-38 132.2 0.0 6.9e-38 131.0 0.0 1.5 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 ORY44934.1 - 0.0011 18.3 0.0 0.0041 16.5 0.0 1.8 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Zn_clus PF00172.18 ORY44935.1 - 2.1e-07 31.0 6.6 4.4e-07 29.9 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY44935.1 - 0.0098 14.9 3.5 0.017 14.1 0.2 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY44936.1 - 8.6e-08 32.2 7.0 1.8e-07 31.1 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY44936.1 - 0.03 13.4 3.0 0.075 12.0 0.1 2.2 2 0 0 2 2 2 0 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY44937.1 - 6e-08 32.7 6.4 1.3e-07 31.6 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY44937.1 - 0.017 14.1 0.2 0.017 14.1 0.2 2.2 2 0 0 2 2 2 0 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY44938.1 - 6e-08 32.7 6.4 1.3e-07 31.6 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY44938.1 - 0.0092 15.0 4.1 0.017 14.1 0.2 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain EF1_GNE PF00736.19 ORY44939.1 - 2.8e-37 126.8 1.9 3e-37 126.7 1.9 1.0 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain ABC_tran PF00005.27 ORY44940.1 - 8.3e-21 74.9 0.0 1.4e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY44940.1 - 4.8e-08 33.2 0.0 0.0013 18.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY44940.1 - 1.4e-07 31.2 0.0 0.01 15.3 0.0 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORY44940.1 - 3.5e-05 24.1 0.0 6.9e-05 23.1 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY44940.1 - 4.6e-05 23.9 0.0 7.4e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 ORY44940.1 - 0.00011 22.8 0.0 0.00017 22.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 ORY44940.1 - 0.00016 21.6 0.1 0.0065 16.4 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 ORY44940.1 - 0.00065 20.1 0.0 0.0011 19.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 ORY44940.1 - 0.0012 18.6 0.1 0.004 16.8 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_14 PF13173.6 ORY44940.1 - 0.0038 17.3 0.0 0.0065 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 ORY44940.1 - 0.0048 16.7 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.15 ORY44940.1 - 0.0048 16.8 0.0 0.0065 16.4 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain NB-ARC PF00931.22 ORY44940.1 - 0.0051 16.0 0.0 0.0082 15.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 ORY44940.1 - 0.0056 16.6 0.0 0.0085 16.0 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 ORY44940.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_30 PF13604.6 ORY44940.1 - 0.015 15.1 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORY44940.1 - 0.021 15.0 0.1 0.04 14.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 ORY44940.1 - 0.034 12.9 0.0 1.8 7.2 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class SbcCD_C PF13558.6 ORY44940.1 - 0.036 14.3 0.0 0.65 10.3 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Adeno_IVa2 PF02456.15 ORY44940.1 - 0.051 12.4 0.1 0.073 11.8 0.1 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein RNA_helicase PF00910.22 ORY44940.1 - 0.065 13.6 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 ORY44940.1 - 0.076 13.0 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.18 ORY44940.1 - 0.081 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_15 PF13175.6 ORY44940.1 - 0.1 12.3 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 ORY44940.1 - 0.12 12.6 0.3 0.21 11.8 0.3 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 ORY44940.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 ORY44940.1 - 0.18 12.3 0.2 0.41 11.2 0.1 1.6 2 0 0 2 2 1 0 AAA domain FSA_C PF10479.9 ORY44941.1 - 0.99 7.5 18.5 1.4 7.0 18.5 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus NOA36 PF06524.12 ORY44942.1 - 0.15 11.4 7.5 0.22 10.8 7.5 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 ORY44942.1 - 0.17 11.0 6.8 0.24 10.5 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.11 ORY44942.1 - 0.35 10.9 2.8 0.55 10.3 2.8 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 ORY44942.1 - 0.42 10.3 2.0 0.4 10.3 0.6 1.7 2 0 0 2 2 2 0 FAM176 family DUF2076 PF09849.9 ORY44942.1 - 0.85 9.6 3.4 1.1 9.2 3.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DNA_pol_phi PF04931.13 ORY44942.1 - 1.6 6.7 5.1 2.1 6.4 5.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi PBP1_TM PF14812.6 ORY44942.1 - 1.9 8.9 17.9 0.15 12.4 12.1 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 ORY44942.1 - 3.4 7.3 9.6 5.9 6.6 9.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.10 ORY44942.1 - 4.7 7.7 14.5 3.2 8.2 12.6 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain HTH_32 PF13565.6 ORY44943.1 - 0.0034 18.0 1.8 0.0038 17.8 0.1 2.0 2 0 0 2 2 2 1 Homeodomain-like domain DUF3391 PF11871.8 ORY44944.1 - 0.025 15.1 0.5 0.15 12.6 0.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) SCF PF02404.15 ORY44945.1 - 0.017 14.4 0.0 0.044 13.1 0.0 1.5 2 0 0 2 2 2 0 Stem cell factor FixS PF03597.15 ORY44945.1 - 0.55 10.0 2.0 1.1 9.0 2.0 1.5 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type O-FucT PF10250.9 ORY44946.1 - 6.2e-21 75.5 0.0 9.7e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase WD40 PF00400.32 ORY44947.1 - 1.1e-14 54.5 5.4 0.00025 21.8 0.4 6.8 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY44947.1 - 4.5e-12 46.1 0.1 0.025 14.9 0.0 5.7 3 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 ORY44947.1 - 0.04 13.2 0.5 11 5.3 0.0 3.0 3 1 0 3 3 3 0 WD40-like domain Ank_2 PF12796.7 ORY44948.1 - 5.2e-32 110.3 6.9 4.8e-17 62.3 1.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY44948.1 - 4.5e-26 90.6 11.2 1.2e-09 38.3 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY44948.1 - 2.2e-24 85.5 6.7 5.4e-12 46.0 0.6 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY44948.1 - 9.6e-23 77.8 2.5 3e-05 24.1 0.1 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 ORY44948.1 - 9.8e-20 70.1 4.1 1.7e-05 25.0 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat P22_CoatProtein PF11651.8 ORY44948.1 - 0.019 13.6 0.1 0.029 13.0 0.0 1.3 2 0 0 2 2 2 0 P22 coat protein - gene protein 5 DUF249 PF03158.13 ORY44948.1 - 0.1 12.3 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Multigene family 530 protein Acetyltransf_3 PF13302.7 ORY44949.1 - 2.5e-48 164.3 0.0 6.9e-31 107.8 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY44949.1 - 1.8e-11 44.3 0.0 3.3e-07 30.5 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 ORY44949.1 - 2.2e-09 37.6 0.0 0.00013 22.2 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 ORY44949.1 - 7.8e-08 32.1 0.0 0.001 18.8 0.0 3.3 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY44949.1 - 0.0093 15.9 0.0 0.081 12.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain PUB PF09409.10 ORY44949.1 - 0.053 13.5 0.0 14 5.7 0.0 2.5 2 0 0 2 2 2 0 PUB domain FR47 PF08445.10 ORY44949.1 - 0.054 13.5 0.1 0.23 11.5 0.0 2.1 3 0 0 3 3 3 0 FR47-like protein AstA PF04958.12 ORY44949.1 - 0.062 11.9 0.0 0.79 8.2 0.0 2.2 2 0 0 2 2 2 0 Arginine N-succinyltransferase beta subunit Fungal_trans PF04082.18 ORY44950.1 - 0.001 18.2 0.7 0.002 17.2 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TFIID-18kDa PF02269.16 ORY44951.1 - 3.9e-28 97.3 0.6 8e-28 96.3 0.2 1.7 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TAFII28 PF04719.14 ORY44951.1 - 0.015 15.4 0.0 0.09 12.9 0.0 2.3 2 1 0 2 2 2 0 hTAFII28-like protein conserved region Rab3-GTPase_cat PF13890.6 ORY44952.1 - 9e-53 178.3 0.2 1.5e-52 177.5 0.2 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit PRKG1_interact PF15898.5 ORY45040.1 - 0.0057 17.5 8.5 0.0057 17.5 8.5 2.3 2 0 0 2 2 2 1 cGMP-dependent protein kinase interacting domain Prp19 PF08606.11 ORY45040.1 - 0.021 14.8 1.1 0.046 13.7 1.1 1.6 1 0 0 1 1 1 0 Prp19/Pso4-like DUF4196 PF13846.6 ORY45040.1 - 0.11 12.7 6.5 0.57 10.4 6.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4196) TFIIA PF03153.13 ORY45040.1 - 0.98 9.3 43.4 0.1 12.6 38.4 1.7 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Toprim_C_rpt PF13368.6 ORY45041.1 - 0.17 11.9 0.0 56 3.8 0.0 3.7 4 0 0 4 4 4 0 Topoisomerase C-terminal repeat TMF_DNA_bd PF12329.8 ORY45042.1 - 0.0079 16.2 0.9 0.022 14.8 0.9 1.7 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Macoilin PF09726.9 ORY45042.1 - 0.15 10.6 3.5 0.19 10.2 3.5 1.1 1 0 0 1 1 1 0 Macoilin family zf-C2H2 PF00096.26 ORY45043.1 - 0.1 13.1 11.0 13 6.4 2.0 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type OrsD PF12013.8 ORY45043.1 - 0.3 11.5 5.8 1.3 9.5 1.7 2.7 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 ORY45043.1 - 9 7.4 12.0 33 5.7 2.4 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger Carn_acyltransf PF00755.20 ORY45045.1 - 1.3e-195 651.5 0.0 1.6e-195 651.2 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Ank_2 PF12796.7 ORY45047.1 - 8.6e-43 144.8 0.3 2.1e-10 41.0 0.0 4.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY45047.1 - 2.1e-17 63.2 0.6 0.00015 22.3 0.0 5.8 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY45047.1 - 7.6e-13 47.4 1.2 1 10.2 0.0 8.1 9 0 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 ORY45047.1 - 4.3e-11 42.8 0.6 0.08 13.3 0.0 6.2 1 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY45047.1 - 1.4e-08 34.8 0.7 1.2 9.7 0.0 6.7 6 3 0 6 6 6 2 Ankyrin repeat BLACT_WH PF17778.1 ORY45047.1 - 0.13 12.2 0.6 2.8 8.0 0.0 3.2 3 1 1 4 4 4 0 Beta-lactamase associated winged helix domain Stig1 PF04885.13 ORY45048.1 - 8.1e-34 117.1 156.9 2.9e-09 37.6 32.3 5.5 2 2 6 8 8 8 6 Stigma-specific protein, Stig1 CorA PF01544.18 ORY45049.1 - 8.1e-43 146.8 0.0 9.4e-43 146.6 0.0 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CybS PF05328.12 ORY45050.1 - 1e-30 106.1 0.4 1.1e-30 106.0 0.4 1.0 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit CybS PF05328.12 ORY45051.1 - 5.1e-32 110.3 0.4 5.8e-32 110.2 0.4 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit zf-C2H2_assoc PF16606.5 ORY45052.1 - 1 9.6 6.7 3.8 7.8 1.4 3.2 2 1 1 3 3 3 0 Unstructured conserved, between two C2H2-type zinc-fingers DUF773 PF05600.12 ORY45055.1 - 0.0032 16.3 4.4 0.0032 16.3 4.4 1.0 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 ADIP PF11559.8 ORY45055.1 - 0.013 15.6 6.2 0.018 15.1 4.4 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding GIDA PF01134.22 ORY45055.1 - 0.061 12.4 2.5 0.07 12.2 2.5 1.0 1 0 0 1 1 1 0 Glucose inhibited division protein A Kinesin_assoc PF16183.5 ORY45055.1 - 0.071 13.3 2.3 0.079 13.1 2.3 1.1 1 0 0 1 1 1 0 Kinesin-associated Syntaxin-6_N PF09177.11 ORY45055.1 - 0.22 12.1 5.4 0.28 11.8 5.4 1.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal MRP-S31 PF15433.6 ORY45055.1 - 0.35 10.5 5.3 0.39 10.4 5.3 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 GTP_cyclohydro2 PF00925.20 ORY45056.1 - 2.1e-60 203.0 0.0 3e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Pkinase PF00069.25 ORY45058.1 - 1.9e-42 145.5 0.0 2.3e-40 138.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY45058.1 - 2.8e-18 66.1 0.0 9.6e-16 57.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 ORY45058.1 - 0.0011 19.0 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY45058.1 - 0.02 14.2 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.20 ORY45058.1 - 0.18 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase_fungal PF17667.1 ORY45058.1 - 0.22 10.3 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DMT_YdcZ PF04657.13 ORY45061.1 - 1.2e-35 122.8 34.4 9.2e-20 71.3 11.8 2.1 2 0 0 2 2 2 2 Putative inner membrane exporter, YdcZ Peptidase_M13_N PF05649.13 ORY45062.1 - 3.7e-58 198.0 1.9 1.4e-57 196.2 1.9 1.8 1 1 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 ORY45062.1 - 1.7e-52 178.0 1.1 1.1e-43 149.3 0.0 2.5 2 0 0 2 2 2 2 Peptidase family M13 ssDNA_TraI_N PF18272.1 ORY45062.1 - 0.03 14.3 0.4 0.15 12.1 0.0 2.3 2 0 0 2 2 2 0 single-stranded DNA binding TraI N-terminal subdomain ELFV_dehydrog PF00208.21 ORY45063.1 - 6.7e-56 189.7 0.0 1.1e-55 189.1 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 ORY45063.1 - 3.1e-25 88.0 0.0 7.8e-18 63.5 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 ORY45063.1 - 0.0033 17.3 0.0 0.0076 16.1 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain LRR_8 PF13855.6 ORY45064.1 - 2.8e-16 59.0 24.4 1.6e-07 30.9 4.9 5.7 4 2 2 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 ORY45064.1 - 1.1e-15 57.5 17.5 6e-05 23.3 0.0 6.3 1 1 9 10 10 10 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY45064.1 - 4.8e-07 29.4 17.8 0.1 13.2 0.2 7.8 7 2 2 9 9 9 2 Leucine Rich Repeat F-box-like PF12937.7 ORY45064.1 - 0.00091 19.1 2.5 0.0013 18.6 0.5 2.3 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.6 ORY45064.1 - 0.0023 17.8 18.3 0.1 12.7 0.0 5.3 7 0 0 7 7 7 2 Leucine Rich repeat F-box PF00646.33 ORY45064.1 - 0.028 14.3 1.0 0.08 12.8 1.0 1.8 1 0 0 1 1 1 0 F-box domain IGR PF09597.10 ORY45065.1 - 1.3e-21 76.4 0.7 2.5e-21 75.5 0.1 1.8 2 0 0 2 2 2 1 IGR protein motif Ribosomal_S13_N PF08069.12 ORY45066.1 - 2.3e-31 107.6 0.1 4e-31 106.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 ORY45066.1 - 2e-14 53.6 0.4 2.8e-14 53.1 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 ORY45066.1 - 0.05 13.5 0.1 0.087 12.7 0.1 1.6 1 1 0 1 1 1 0 'Paired box' domain ABC1 PF03109.16 ORY45067.1 - 4.3e-18 65.6 0.0 1.3e-17 64.1 0.0 1.7 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 ORY45067.1 - 0.086 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Sugarporin_N PF11471.8 ORY45068.1 - 0.1 12.6 0.4 1.9 8.5 0.1 2.2 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension LigB PF02900.18 ORY45071.1 - 4.9e-36 124.2 0.0 5.7e-36 124.0 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase HlyIII PF03006.20 ORY45072.1 - 1.4e-50 172.1 21.7 1.8e-50 171.8 21.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF2304 PF10066.9 ORY45072.1 - 3.8 7.8 9.8 0.77 10.0 5.7 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) LRR_8 PF13855.6 ORY45075.1 - 4.9e-15 55.0 25.5 3.9e-08 32.9 5.6 3.4 1 1 3 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 ORY45075.1 - 3.6e-08 33.6 13.1 0.021 15.3 2.3 5.1 2 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY45075.1 - 0.00034 20.8 13.8 0.27 11.9 0.2 6.3 6 0 0 6 6 6 2 Leucine Rich Repeat F-box-like PF12937.7 ORY45075.1 - 0.0011 18.8 0.0 0.0053 16.6 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY45075.1 - 0.0032 17.3 0.3 0.012 15.5 0.1 2.0 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.6 ORY45075.1 - 0.005 16.8 9.3 1.9 8.8 0.2 4.8 5 0 0 5 5 5 2 Leucine Rich repeat Asp PF00026.23 ORY45076.1 - 8.2e-59 199.6 2.5 1.2e-58 199.0 2.5 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY45076.1 - 1.1e-08 35.5 7.0 1.7e-07 31.7 1.9 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORY45076.1 - 0.0021 18.7 0.2 0.21 12.3 0.1 3.8 2 1 0 2 2 2 1 Aspartyl protease LRR_8 PF13855.6 ORY45077.1 - 2.3e-10 40.1 14.0 3.6e-08 33.1 4.2 4.3 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 ORY45077.1 - 5.4e-08 33.0 16.8 2e-06 28.0 2.5 5.3 3 2 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY45077.1 - 0.062 13.9 17.3 4.3 8.3 0.6 6.1 6 0 0 6 6 6 0 Leucine Rich Repeat HpcH_HpaI PF03328.14 ORY45078.1 - 2.3e-47 161.0 0.1 3e-47 160.6 0.1 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 ORY45078.1 - 8.4e-19 67.9 0.0 7.2e-11 41.8 0.0 2.1 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.21 ORY45078.1 - 0.00089 18.2 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain LRR_9 PF14580.6 ORY45079.1 - 2.4e-51 173.7 0.2 2.9e-51 173.4 0.2 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 ORY45079.1 - 6.8e-11 41.8 0.3 2.7e-10 39.9 0.5 1.8 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 ORY45079.1 - 1.5e-05 25.2 6.3 0.00056 20.2 0.6 3.5 2 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY45079.1 - 0.012 16.0 2.8 8.4 7.4 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich Repeat Sod_Cu PF00080.20 ORY45080.1 - 1.2e-28 100.0 1.0 1.4e-28 99.9 1.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) RTA1 PF04479.13 ORY45081.1 - 6.6e-52 176.1 9.3 8.2e-52 175.8 9.3 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF5418 PF17439.2 ORY45081.1 - 0.03 14.4 1.4 0.078 13.1 1.4 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5418) DUF3671 PF12420.8 ORY45081.1 - 7.6 6.6 6.8 0.85 9.7 2.3 1.7 2 0 0 2 2 2 0 Protein of unknown function PIG-S PF10510.9 ORY45082.1 - 1.2e-108 364.2 5.3 1.4e-101 340.9 0.5 2.0 1 1 1 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein SIR2_2 PF13289.6 ORY45083.1 - 9.2e-07 29.1 0.0 4.1e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 SIR2-like domain GATA PF00320.27 ORY45084.1 - 4e-15 55.1 5.0 6.6e-15 54.4 5.0 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.12 ORY45084.1 - 0.012 15.9 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 PAS fold Nudix_N_2 PF14803.6 ORY45084.1 - 0.054 13.4 1.1 0.11 12.4 1.1 1.4 1 0 0 1 1 1 0 Nudix N-terminal DZR PF12773.7 ORY45084.1 - 0.07 13.2 0.6 0.14 12.2 0.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon FAM76 PF16046.5 ORY45084.1 - 0.15 11.4 5.9 0.13 11.5 4.5 1.6 2 0 0 2 2 2 0 FAM76 protein TFIIA PF03153.13 ORY45084.1 - 0.3 11.1 15.7 0.24 11.3 13.2 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CDV3 PF15359.6 ORY45084.1 - 1.1 9.7 7.9 5.6 7.4 6.0 2.4 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 Ank_2 PF12796.7 ORY45085.1 - 6.4e-12 45.9 0.3 7.7e-07 29.6 0.1 3.5 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY45085.1 - 0.00029 21.0 0.4 11 6.9 0.1 4.6 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 ORY45085.1 - 0.00055 20.2 1.7 0.86 10.0 0.2 3.8 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY45085.1 - 0.0024 18.4 1.3 0.13 12.9 0.1 3.6 2 2 2 4 4 4 2 Ankyrin repeats (many copies) OSCP PF00213.18 ORY45085.1 - 0.12 12.5 0.5 3.6 7.7 0.0 3.0 2 1 1 3 3 3 0 ATP synthase delta (OSCP) subunit Ank_2 PF12796.7 ORY45086.1 - 3.1e-21 75.7 0.0 3.3e-07 30.8 0.0 4.7 3 2 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY45086.1 - 2.7e-08 33.4 1.7 7.4 7.5 0.0 9.0 10 0 0 10 10 10 2 Ankyrin repeat Ank_4 PF13637.6 ORY45086.1 - 4.9e-07 30.2 2.7 7.4 7.3 0.0 7.4 5 2 1 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY45086.1 - 2.7e-06 27.6 1.7 28 5.4 0.0 7.6 8 0 0 8 8 8 0 Ankyrin repeat Ank_5 PF13857.6 ORY45086.1 - 0.0015 18.8 1.2 0.42 11.0 0.0 5.0 5 1 2 7 7 7 1 Ankyrin repeats (many copies) F-box PF00646.33 ORY45086.1 - 0.016 15.1 0.1 0.061 13.2 0.1 2.1 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 ORY45086.1 - 0.081 12.8 0.1 0.23 11.4 0.1 1.8 1 0 0 1 1 1 0 F-box-like TTc_toxin_rep PF18807.1 ORY45091.1 - 6.4e-11 41.9 8.8 7 6.6 0.0 8.5 6 1 3 9 9 9 5 Tripartite Tc toxins repeat VQ PF05678.14 ORY45091.1 - 0.091 12.3 2.6 18 4.9 0.0 4.9 6 0 0 6 6 6 0 VQ motif PA_decarbox PF05870.11 ORY45091.1 - 0.15 11.7 0.6 22 4.7 0.0 2.8 2 1 1 3 3 3 0 Phenolic acid decarboxylase (PAD) DUF3349 PF11829.8 ORY45091.1 - 1.5 9.6 17.3 41 5.0 1.4 6.2 1 1 5 6 6 6 0 Protein of unknown function (DUF3349) DUF257 PF03192.13 ORY45091.1 - 1.5 8.6 4.5 5.9 6.6 0.3 2.8 2 1 2 4 4 4 0 Pyrococcus protein of unknown function, DUF257 SOAR PF16533.5 ORY45091.1 - 2.8 8.0 4.0 9.7 6.2 0.1 3.4 3 2 1 4 4 4 0 STIM1 Orai1-activating region Rotamase_3 PF13616.6 ORY45093.1 - 1.6e-12 48.0 0.0 2.9e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 ORY45093.1 - 2e-12 47.9 0.0 3.8e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 ORY45093.1 - 4.6e-07 30.7 0.0 2.1e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 ORY45094.1 - 3.6e-20 72.6 0.0 4.9e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 ORY45094.1 - 2.1e-19 70.3 0.1 2.9e-19 69.8 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 ORY45094.1 - 3.1e-07 31.2 0.0 4.7e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Nif11 PF07862.11 ORY45094.1 - 0.024 15.0 0.4 0.047 14.0 0.4 1.4 1 0 0 1 1 1 0 Nif11 domain S1FA PF04689.13 ORY45095.1 - 0.16 12.1 2.0 0.39 10.9 0.1 2.3 1 1 1 2 2 2 0 DNA binding protein S1FA Endothelin PF00322.17 ORY45097.1 - 0.12 12.0 0.2 0.33 10.6 0.1 1.8 2 0 0 2 2 2 0 Endothelin family WRW PF10206.9 ORY45098.1 - 0.071 13.5 0.1 0.15 12.4 0.0 1.6 1 1 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f AAA PF00004.29 ORY45099.1 - 7.6e-86 285.2 0.0 8.2e-45 152.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY45099.1 - 1.1e-25 89.1 2.8 1.2e-14 53.8 0.3 2.9 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 ORY45099.1 - 5.5e-10 39.2 0.0 4.4e-07 29.8 0.0 3.1 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ORY45099.1 - 5.8e-10 39.5 0.0 3.3e-05 24.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 ORY45099.1 - 4.4e-07 30.4 0.2 8.2e-05 23.1 0.1 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY45099.1 - 2.5e-06 27.8 0.6 0.007 16.6 0.4 3.4 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 ORY45099.1 - 2.7e-06 27.1 0.1 1.1 8.8 0.0 3.7 3 0 0 3 3 3 3 AAA domain AAA_5 PF07728.14 ORY45099.1 - 4.7e-06 26.7 0.5 0.00036 20.5 0.1 3.3 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 ORY45099.1 - 9.5e-06 25.7 0.0 0.0021 18.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORY45099.1 - 2.2e-05 24.6 0.0 0.0002 21.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 ORY45099.1 - 5.3e-05 22.6 0.1 0.00067 19.0 0.0 2.7 4 0 0 4 4 4 1 TIP49 P-loop domain AAA_18 PF13238.6 ORY45099.1 - 0.00041 20.9 0.1 0.023 15.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 ORY45099.1 - 0.005 16.6 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 ORY45099.1 - 0.0092 15.7 0.1 0.42 10.3 0.0 3.2 2 2 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.6 ORY45099.1 - 0.018 14.8 0.0 0.053 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ORY45099.1 - 0.031 14.5 0.0 0.094 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 ORY45099.1 - 0.034 13.5 0.1 0.069 12.5 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 ORY45099.1 - 0.039 13.3 0.1 0.3 10.4 0.0 2.4 1 1 0 1 1 1 0 KaiC RNA_helicase PF00910.22 ORY45099.1 - 0.065 13.6 0.0 0.19 12.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase IPT PF01745.16 ORY45099.1 - 0.074 12.4 0.1 0.15 11.4 0.1 1.4 1 0 0 1 1 1 0 Isopentenyl transferase AAA_7 PF12775.7 ORY45099.1 - 0.14 11.7 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 ORY45099.1 - 0.14 11.3 0.0 0.36 10.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NACHT PF05729.12 ORY45099.1 - 0.17 11.8 0.2 4.3 7.2 0.0 2.7 3 0 0 3 3 3 0 NACHT domain Parvo_NS1 PF01057.17 ORY45099.1 - 0.23 10.5 0.0 0.44 9.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CDH-cyt PF16010.5 ORY45100.1 - 2.2e-26 92.7 4.0 7.9e-17 61.5 0.4 2.6 2 1 0 2 2 2 2 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 ORY45100.1 - 1.2e-09 38.5 1.1 0.00043 20.5 0.1 2.5 2 0 0 2 2 2 2 DOMON domain Cytochrom_B561 PF03188.16 ORY45100.1 - 0.36 11.0 3.4 1.1 9.4 1.4 2.7 2 1 0 2 2 2 0 Eukaryotic cytochrome b561 Aminotran_1_2 PF00155.21 ORY45101.1 - 4e-25 88.8 0.0 1.7e-23 83.4 0.0 2.7 2 1 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 ORY45101.1 - 0.051 12.8 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase B12D PF06522.11 ORY45102.1 - 1e-05 25.2 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit L51_S25_CI-B8 PF05047.16 ORY45103.1 - 1.5e-10 40.8 0.0 2e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Rep_N PF08724.10 ORY45103.1 - 0.072 12.8 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 Rep protein catalytic domain like OmpH PF03938.14 ORY45104.1 - 0.23 11.8 6.2 0.4 11.0 6.2 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3037 PF11236.8 ORY45104.1 - 0.31 11.5 2.4 1.4 9.3 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) DUF2335 PF10097.9 ORY45104.1 - 0.52 10.3 4.5 1.7 8.7 4.5 1.9 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) PRKG1_interact PF15898.5 ORY45104.1 - 3 8.8 9.4 29 5.6 9.1 2.5 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain MCM3AP_GANP PF16769.5 ORY45105.1 - 3.3e-05 22.4 0.0 3.7e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 MCM3AP domain of GANP SAC3_GANP PF03399.16 ORY45107.1 - 0.00029 20.3 0.3 0.00047 19.6 0.1 1.4 2 0 0 2 2 2 1 SAC3/GANP family Ku_N PF03731.15 ORY45107.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain GATA PF00320.27 ORY45108.1 - 8.5e-08 31.7 1.9 2e-07 30.5 1.9 1.7 1 0 0 1 1 1 1 GATA zinc finger TAP35_44 PF07265.11 ORY45108.1 - 0.043 13.8 0.7 0.11 12.6 0.7 1.6 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 FAD_binding_3 PF01494.19 ORY45109.1 - 2e-18 66.8 0.1 1.4e-15 57.4 0.1 2.4 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ORY45109.1 - 1.3e-10 41.0 0.2 3.9e-06 26.3 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY45109.1 - 1.8e-07 30.7 0.3 0.0015 17.9 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY45109.1 - 3.6e-06 25.9 0.1 6.1e-05 21.9 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 ORY45109.1 - 1.6e-05 25.1 0.0 3.3e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 ORY45109.1 - 2.3e-05 23.4 0.2 0.13 11.1 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.22 ORY45109.1 - 0.00023 20.3 0.2 0.00039 19.6 0.2 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 ORY45109.1 - 0.0003 20.0 0.3 0.00097 18.3 0.3 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 ORY45109.1 - 0.0006 19.8 0.1 1.3 9.0 0.0 2.2 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 ORY45109.1 - 0.0009 18.4 0.1 0.0016 17.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ORY45109.1 - 0.0031 18.0 0.0 0.17 12.5 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY45109.1 - 0.0076 15.9 0.1 0.091 12.3 0.1 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ORY45109.1 - 0.021 14.2 0.1 0.038 13.3 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.16 ORY45109.1 - 0.054 13.1 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FMO-like PF00743.19 ORY45109.1 - 0.091 11.2 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like AdoHcyase_NAD PF00670.21 ORY45109.1 - 0.11 12.6 0.2 0.86 9.7 0.2 2.3 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GATA PF00320.27 ORY45111.1 - 8.2e-35 118.1 19.6 5.6e-16 57.9 4.4 3.3 3 0 0 3 3 3 3 GATA zinc finger TF_Zn_Ribbon PF08271.12 ORY45111.1 - 1.2e-06 28.0 9.5 0.0014 18.1 1.6 2.3 2 0 0 2 2 2 2 TFIIB zinc-binding Elf1 PF05129.13 ORY45111.1 - 8.2e-06 25.8 2.6 0.0016 18.5 0.1 2.9 3 0 0 3 3 3 2 Transcription elongation factor Elf1 like Zn-ribbon_8 PF09723.10 ORY45111.1 - 3.4e-05 23.9 5.0 0.0038 17.3 0.1 2.8 3 0 0 3 3 3 2 Zinc ribbon domain Auto_anti-p27 PF06677.12 ORY45111.1 - 5.1e-05 23.3 4.5 0.0097 16.0 0.4 2.5 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OTT_1508_deam PF14441.6 ORY45111.1 - 7.1e-05 22.7 2.2 2.7 8.1 0.1 3.5 4 0 0 4 4 3 2 OTT_1508-like deaminase ArfGap PF01412.18 ORY45111.1 - 0.00032 20.8 1.6 0.024 14.7 0.1 2.3 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf eIF-5_eIF-2B PF01873.17 ORY45111.1 - 0.01 15.7 6.2 0.21 11.5 0.2 2.3 2 0 0 2 2 2 2 Domain found in IF2B/IF5 Prim_Zn_Ribbon PF08273.12 ORY45111.1 - 0.012 15.8 12.1 0.064 13.5 3.7 2.8 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase TDP43_N PF18694.1 ORY45111.1 - 0.025 14.4 0.1 5.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Transactive response DNA-binding protein N-terminal domain DZR PF12773.7 ORY45111.1 - 0.092 12.8 10.3 0.78 9.8 6.6 3.4 2 1 1 3 3 3 0 Double zinc ribbon OrfB_Zn_ribbon PF07282.11 ORY45111.1 - 0.42 10.6 9.2 0.58 10.1 0.6 2.8 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Rpr2 PF04032.16 ORY45111.1 - 1.6 9.1 5.7 51 4.2 0.0 3.5 1 1 2 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-RRN7 PF11781.8 ORY45111.1 - 3.7 7.3 13.9 2.4 7.9 0.3 3.8 3 1 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 GATA PF00320.27 ORY45112.1 - 1.8e-20 72.2 14.2 1e-14 53.9 2.5 2.3 2 0 0 2 2 2 2 GATA zinc finger Zn-ribbon_8 PF09723.10 ORY45112.1 - 0.0019 18.3 2.0 0.78 9.9 0.1 2.6 2 0 0 2 2 2 2 Zinc ribbon domain ArfGap PF01412.18 ORY45112.1 - 0.0033 17.5 4.2 1.2 9.2 0.6 2.7 2 1 0 2 2 2 2 Putative GTPase activating protein for Arf OrfB_Zn_ribbon PF07282.11 ORY45112.1 - 0.027 14.4 2.5 3.8 7.5 0.2 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DZR PF12773.7 ORY45112.1 - 0.069 13.2 6.9 6.4 6.9 7.4 2.9 1 1 1 2 2 2 0 Double zinc ribbon zf-RRN7 PF11781.8 ORY45112.1 - 0.14 11.9 0.4 0.14 11.9 0.4 2.9 3 0 0 3 3 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 FYVE PF01363.21 ORY45112.1 - 0.36 11.0 3.3 7.6 6.7 0.6 2.5 2 0 0 2 2 2 0 FYVE zinc finger Rpr2 PF04032.16 ORY45112.1 - 0.41 10.9 4.0 14 6.1 1.3 3.5 3 1 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain TF_Zn_Ribbon PF08271.12 ORY45112.1 - 0.47 10.0 4.5 0.21 11.1 0.3 2.5 3 0 0 3 3 3 0 TFIIB zinc-binding ADK_lid PF05191.14 ORY45112.1 - 0.52 10.3 3.0 28 4.8 0.0 3.4 3 1 0 3 3 3 0 Adenylate kinase, active site lid Nudix_N_2 PF14803.6 ORY45112.1 - 0.65 10.0 10.3 1 9.3 1.9 3.2 3 0 0 3 3 3 0 Nudix N-terminal DUF3039 PF11238.8 ORY45112.1 - 0.87 9.4 3.9 0.68 9.7 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3039) zf-NADH-PPase PF09297.11 ORY45112.1 - 0.99 9.1 0.1 0.99 9.1 0.1 3.6 4 0 0 4 4 4 0 NADH pyrophosphatase zinc ribbon domain Auto_anti-p27 PF06677.12 ORY45112.1 - 1.4 9.1 6.4 0.62 10.3 0.6 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-piccolo PF05715.13 ORY45112.1 - 2.1 8.6 8.8 5.3 7.3 0.4 3.4 2 1 1 3 3 3 0 Piccolo Zn-finger Vps36-NZF-N PF16988.5 ORY45112.1 - 3.2 7.2 12.9 2.5 7.6 0.4 3.9 3 1 1 4 4 4 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zinc_ribbon_2 PF13240.6 ORY45112.1 - 4.1 7.3 9.9 8.5 6.2 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain Zn_ribbon_recom PF13408.6 ORY45112.1 - 9.2 6.9 11.1 3.5 8.2 0.4 3.1 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain GATA PF00320.27 ORY45113.1 - 0.0017 17.9 4.4 0.0028 17.2 4.4 1.3 1 0 0 1 1 1 1 GATA zinc finger F-box-like PF12937.7 ORY45114.1 - 0.00011 22.0 0.2 0.00051 19.9 0.1 2.1 2 0 0 2 2 2 1 F-box-like KCH PF16944.5 ORY45115.1 - 1e-36 127.0 11.0 1.2e-36 126.7 11.0 1.1 1 0 0 1 1 1 1 Fungal potassium channel DUF3139 PF11337.8 ORY45115.1 - 0.16 12.6 1.4 0.23 12.1 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) LRR_8 PF13855.6 ORY45116.1 - 4.9e-12 45.4 8.1 1.3e-05 24.9 0.5 4.0 1 1 4 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 ORY45116.1 - 3.7e-07 30.4 9.1 0.038 14.4 0.1 4.7 2 2 4 6 6 6 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORY45116.1 - 0.00082 19.2 0.1 0.0023 17.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 ORY45116.1 - 0.00083 19.6 16.2 0.66 10.8 0.3 7.4 7 1 0 7 7 7 1 Leucine Rich Repeat F-box PF00646.33 ORY45116.1 - 0.0021 17.9 2.3 0.0023 17.8 0.7 1.9 2 0 0 2 2 2 1 F-box domain KCH PF16944.5 ORY45117.1 - 3.1e-52 177.8 19.0 7.9e-52 176.5 19.0 1.6 1 1 0 1 1 1 1 Fungal potassium channel SH3_9 PF14604.6 ORY45118.1 - 3e-06 27.0 0.1 1.5e-05 24.8 0.1 2.1 1 1 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY45118.1 - 0.00055 19.5 0.0 0.0011 18.5 0.0 1.6 1 1 0 1 1 1 1 SH3 domain EphA2_TM PF14575.6 ORY45118.1 - 0.093 13.6 0.0 0.18 12.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAD_binding_3 PF01494.19 ORY45119.1 - 1.4e-23 83.8 1.0 7.7e-12 45.1 0.0 3.3 3 1 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 ORY45119.1 - 2.1e-07 30.5 0.6 1.4e-05 24.5 0.1 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY45119.1 - 1.3e-05 25.4 0.0 2.7e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ORY45119.1 - 1.4e-05 24.0 0.1 0.00018 20.3 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 ORY45119.1 - 0.00016 20.9 0.2 0.00025 20.3 0.2 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 ORY45119.1 - 0.00025 20.7 0.0 0.086 12.4 0.1 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ORY45119.1 - 0.00042 19.3 0.1 0.19 10.6 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.6 ORY45119.1 - 0.001 18.4 0.3 0.0029 16.9 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY45119.1 - 0.0012 18.0 0.1 0.0017 17.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ORY45119.1 - 0.0097 15.3 0.2 0.014 14.8 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORY45119.1 - 0.012 15.6 0.1 1 9.3 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 ORY45119.1 - 0.076 12.0 0.0 4.8 6.1 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.16 ORY45119.1 - 0.08 12.6 0.0 0.35 10.5 0.0 2.1 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 ORY45119.1 - 0.083 13.5 0.0 0.83 10.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY45120.1 - 6.2e-18 65.1 0.0 7.5e-09 35.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 ORY45120.1 - 0.0046 15.9 0.0 0.14 11.0 0.0 2.0 2 0 0 2 2 2 2 Tryptophan halogenase Sod_Cu PF00080.20 ORY45122.1 - 2.9e-28 98.8 0.5 3.7e-28 98.5 0.5 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.12 ORY45122.1 - 0.0024 18.8 0.7 0.0031 18.5 0.7 1.3 1 0 0 1 1 1 1 CHRD domain Pentapeptide_2 PF01469.18 ORY45124.1 - 0.64 9.9 33.1 0.24 11.3 28.2 2.4 2 1 0 2 2 2 0 Pentapeptide repeats (8 copies) DUF4841 PF16129.5 ORY45125.1 - 0.041 14.1 2.8 2.4 8.5 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4841) DUF1180 PF06679.12 ORY45125.1 - 8.9 6.7 5.4 1.6 9.1 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Sod_Cu PF00080.20 ORY45126.1 - 4.1e-31 108.1 4.6 1.4e-30 106.3 2.4 2.1 2 0 0 2 2 2 1 Copper/zinc superoxide dismutase (SODC) Chromo PF00385.24 ORY45127.1 - 0.00026 20.9 0.3 0.00048 20.0 0.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF325 PF03804.13 ORY45127.1 - 0.02 14.9 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Viral proteins of unknown function AJAP1_PANP_C PF15298.6 ORY45127.1 - 0.042 14.0 3.8 0.065 13.4 3.8 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Tudor-knot PF11717.8 ORY45127.1 - 0.061 13.2 0.2 0.16 11.9 0.2 1.8 1 1 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF2465 PF10239.9 ORY45127.1 - 0.14 11.4 1.0 0.18 11.0 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2465) TAXi_C PF14541.6 ORY45128.1 - 1.1e-15 57.7 0.0 1.6e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.23 ORY45128.1 - 2.2e-14 53.6 0.4 2.9e-14 53.2 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Methyltr_RsmB-F PF01189.17 ORY45129.1 - 2.6e-23 82.7 0.0 4.2e-16 59.2 0.0 2.2 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Methyltransf_25 PF13649.6 ORY45129.1 - 9.9e-07 29.4 0.1 0.00094 19.8 0.0 2.6 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.12 ORY45129.1 - 9.4e-05 23.0 0.1 0.82 10.4 0.0 2.8 2 1 1 3 3 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 ORY45129.1 - 0.0001 22.1 0.0 0.031 14.1 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 ORY45129.1 - 0.0027 17.6 0.0 0.0057 16.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY45129.1 - 0.011 16.5 0.1 7.2 7.4 0.0 3.1 3 0 0 3 3 3 0 Methyltransferase domain MTS PF05175.14 ORY45129.1 - 0.12 12.0 0.0 0.31 10.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain FtsJ PF01728.19 ORY45129.1 - 0.19 11.9 0.1 0.67 10.0 0.1 2.0 1 1 0 1 1 1 0 FtsJ-like methyltransferase HA2 PF04408.23 ORY45130.1 - 6.3e-17 61.8 2.5 9.6e-17 61.2 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) DUF2196 PF09962.9 ORY45130.1 - 1.9e-15 56.6 0.3 6.6e-15 54.9 0.3 2.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) OB_NTP_bind PF07717.16 ORY45130.1 - 2e-12 47.3 0.0 6.1e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 ORY45130.1 - 5.3e-08 32.8 0.1 1.1e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY45130.1 - 5.8e-08 33.1 0.0 1.9e-07 31.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.22 ORY45130.1 - 7.2e-08 32.7 0.0 2.6e-07 30.9 0.0 2.0 1 0 0 1 1 1 1 RWD domain AAA_22 PF13401.6 ORY45130.1 - 0.0005 20.4 1.0 0.0024 18.1 1.0 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 ORY45130.1 - 0.0018 18.3 0.0 0.015 15.3 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit ATPase PF06745.13 ORY45130.1 - 0.042 13.2 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 KaiC T2SSE PF00437.20 ORY45130.1 - 0.065 12.3 0.1 0.16 11.0 0.1 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 ORY45130.1 - 0.45 11.0 0.0 0.45 11.0 0.0 2.7 2 0 0 2 2 1 0 AAA domain peroxidase PF00141.23 ORY45131.1 - 4.3e-53 180.4 0.0 5.7e-53 180.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase GCV_H PF01597.19 ORY45132.1 - 1.8e-27 95.6 0.3 2.3e-27 95.3 0.3 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 ORY45132.1 - 0.014 15.2 0.1 0.021 14.6 0.1 1.3 1 0 0 1 1 1 0 Biotin-requiring enzyme RnfC_N PF13375.6 ORY45132.1 - 0.036 14.0 0.1 0.056 13.4 0.1 1.3 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Dimer_Tnp_Tn5 PF02281.16 ORY45133.1 - 0.1 12.3 0.2 0.14 11.8 0.2 1.2 1 0 0 1 1 1 0 Transposase Tn5 dimerisation domain zf-C2H2_3 PF13878.6 ORY45134.1 - 0.21 11.5 0.2 0.21 11.5 0.2 3.6 4 0 0 4 4 4 0 zinc-finger of acetyl-transferase ESCO TauD PF02668.16 ORY45135.1 - 1e-36 127.1 0.3 5.1e-36 124.8 0.3 1.8 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Mpv17_PMP22 PF04117.12 ORY45136.1 - 2.5e-13 50.0 0.7 4.4e-13 49.3 0.7 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF604 PF04646.12 ORY45137.1 - 3.3e-07 30.0 0.8 5.4e-07 29.3 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF604 PAN_4 PF14295.6 ORY45137.1 - 4.4e-07 29.7 0.7 9.6e-07 28.6 0.2 1.8 2 0 0 2 2 2 1 PAN domain Methyltransf_21 PF05050.12 ORY45138.1 - 4.3e-13 49.6 0.0 7.7e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Peptidase_C58 PF03543.14 ORY45138.1 - 0.0096 15.7 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 1 Yersinia/Haemophilus virulence surface antigen BMF PF15185.6 ORY45138.1 - 0.075 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis DUF938 PF06080.12 ORY45138.1 - 0.1 12.3 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) CFEM PF05730.11 ORY45139.1 - 0.0069 16.5 11.9 0.0083 16.2 2.2 2.6 2 1 0 2 2 2 2 CFEM domain Inositol_P PF00459.25 ORY45140.1 - 6.4e-66 222.7 0.1 7.5e-66 222.4 0.1 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family BTB PF00651.31 ORY45141.1 - 3.6e-06 27.2 0.0 5.5e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain MFS_1 PF07690.16 ORY45142.1 - 2.3e-13 49.8 20.7 4.1e-13 49.0 20.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY45142.1 - 1.4e-11 44.3 3.9 9.7e-05 22.1 1.0 2.8 2 0 0 2 2 2 2 Ion channel regulatory protein UNC-93 zf-C3HC4_2 PF13923.6 ORY45143.1 - 7.8e-10 38.4 1.8 1.4e-09 37.7 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY45143.1 - 3e-09 37.1 1.4 5.1e-09 36.3 1.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 ORY45143.1 - 3.8e-09 36.7 0.7 5.4e-09 36.2 0.7 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 ORY45143.1 - 2.2e-07 30.7 0.4 3.3e-07 30.1 0.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY45143.1 - 1.6e-06 27.9 1.2 2.1e-06 27.5 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 ORY45143.1 - 1.1e-05 24.9 2.2 1.4e-05 24.6 1.3 1.6 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 ORY45143.1 - 1.3e-05 25.0 0.5 2e-05 24.3 0.5 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 ORY45143.1 - 2.4e-05 24.1 1.0 2.4e-05 24.1 1.0 1.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY45143.1 - 2.5e-05 24.2 4.3 2.6e-05 24.1 0.9 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 ORY45143.1 - 0.00028 20.9 1.0 0.00054 20.0 1.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 ORY45143.1 - 0.00046 19.9 3.6 0.00061 19.5 0.2 2.5 3 0 0 3 3 3 1 RING-like zinc finger RINGv PF12906.7 ORY45143.1 - 0.016 15.3 1.2 0.031 14.4 1.2 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 ORY45143.1 - 0.2 12.0 1.2 0.36 11.2 1.2 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3H2C3 PF17122.5 ORY45143.1 - 0.38 10.8 2.7 1.2 9.2 2.7 1.9 1 1 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 ORY45143.1 - 1 9.6 4.1 5.7 7.2 4.1 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain PDT PF00800.18 ORY45145.1 - 2.5e-59 200.2 0.4 3.1e-59 199.9 0.4 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 ORY45145.1 - 1.1e-07 31.5 0.0 2.2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 ACT domain DUF1970 PF09301.10 ORY45145.1 - 0.0064 16.7 0.1 0.012 15.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1970) Exo_endo_phos PF03372.23 ORY45146.1 - 2.8e-09 36.8 0.0 6.5e-09 35.6 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 ORY45146.1 - 5.3e-06 26.4 2.3 0.00024 21.2 0.3 2.6 2 0 0 2 2 2 2 GRF zinc finger Exo_endo_phos_2 PF14529.6 ORY45146.1 - 0.034 14.0 0.1 0.23 11.3 0.0 2.2 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase CDC27 PF09507.10 ORY45146.1 - 0.21 10.9 0.3 0.59 9.5 0.1 1.7 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 CDP-OH_P_tran_2 PF08009.11 ORY45148.1 - 0.011 15.6 2.2 0.013 15.4 0.3 2.2 2 0 0 2 2 2 0 CDP-alcohol phosphatidyltransferase 2 RB_A PF01858.17 ORY45148.1 - 0.025 14.4 0.1 0.033 14.0 0.1 1.1 1 0 0 1 1 1 0 Retinoblastoma-associated protein A domain adh_short PF00106.25 ORY45151.1 - 3.5e-23 82.1 0.2 4.4e-23 81.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY45151.1 - 1e-11 44.8 0.0 1.4e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY45151.1 - 1.1e-06 28.7 0.1 1.5e-06 28.3 0.1 1.1 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 ORY45151.1 - 0.021 14.2 0.2 0.038 13.4 0.1 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase O-ag_pol_Wzy PF14296.6 ORY45151.1 - 0.023 13.4 0.8 0.027 13.1 0.8 1.1 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy Epimerase PF01370.21 ORY45151.1 - 0.068 12.6 0.6 0.088 12.3 0.1 1.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 ORY45152.1 - 1.6e-08 34.2 0.0 0.0032 16.9 0.0 2.0 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY45152.1 - 0.00033 20.3 0.0 0.023 14.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 ORY45152.1 - 0.053 13.0 0.0 0.063 12.7 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ChaC PF04752.12 ORY45153.1 - 1.3e-48 165.4 0.0 1.5e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein LRR_8 PF13855.6 ORY45154.1 - 3.3e-07 29.9 1.4 0.009 15.8 0.1 3.1 2 1 1 3 3 3 2 Leucine rich repeat F-box PF00646.33 ORY45154.1 - 0.0013 18.5 0.8 0.0023 17.7 0.8 1.4 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 ORY45154.1 - 0.0016 18.8 1.2 1.9 9.0 0.1 3.5 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORY45154.1 - 0.0026 17.6 1.4 0.0049 16.7 1.4 1.4 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 ORY45154.1 - 0.1 13.2 0.4 1.2e+02 3.8 0.0 4.4 4 1 0 4 4 4 0 Leucine Rich Repeat DUF761 PF05553.11 ORY45155.1 - 0.15 11.6 0.4 0.41 10.2 0.4 1.7 1 0 0 1 1 1 0 Cotton fibre expressed protein Fringe PF02434.16 ORY45156.1 - 7.9e-11 41.9 0.0 1.4e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.12 ORY45156.1 - 7.1e-10 38.7 0.1 1.1e-09 38.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Galactosyl_T PF01762.21 ORY45156.1 - 4.2e-08 33.3 0.0 0.0001 22.2 0.0 2.2 2 0 0 2 2 2 2 Galactosyltransferase Nitro_FeMo-Co PF02579.17 ORY45156.1 - 0.094 13.1 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor MIP PF00230.20 ORY45158.1 - 2.1e-48 165.0 11.9 2.7e-48 164.7 11.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 ORY45159.1 - 3.4e-48 164.3 9.2 5.6e-48 163.6 9.2 1.3 1 1 0 1 1 1 1 Major intrinsic protein DUF4651 PF15513.6 ORY45159.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) DUF604 PF04646.12 ORY45160.1 - 5.6e-06 25.9 0.1 9.8e-06 25.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 PAN_4 PF14295.6 ORY45160.1 - 5.9e-06 26.1 1.9 5.9e-06 26.1 1.9 2.1 2 0 0 2 2 2 1 PAN domain PAN_1 PF00024.26 ORY45160.1 - 7.1e-05 22.7 0.0 0.00014 21.8 0.0 1.4 1 0 0 1 1 1 1 PAN domain Fringe PF02434.16 ORY45160.1 - 0.00025 20.6 0.2 0.42 10.0 0.0 2.4 2 1 0 2 2 2 2 Fringe-like Galactosyl_T PF01762.21 ORY45160.1 - 0.0026 17.6 0.0 0.25 11.1 0.0 2.7 2 1 1 3 3 3 1 Galactosyltransferase DUF604 PF04646.12 ORY45161.1 - 8.2e-08 31.9 0.1 1.4e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Glyco_tranf_2_4 PF13704.6 ORY45161.1 - 0.13 12.8 0.2 0.29 11.7 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 2 LRR_8 PF13855.6 ORY45162.1 - 0.01 15.6 12.7 0.087 12.6 1.3 3.0 2 1 1 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 ORY45162.1 - 0.69 10.7 14.7 34 5.5 0.4 4.9 4 1 0 4 4 4 0 Leucine Rich Repeat DUF604 PF04646.12 ORY45163.1 - 5.9e-07 29.1 0.5 1.7e-06 27.6 0.2 1.9 1 1 1 2 2 2 1 Protein of unknown function, DUF604 Fringe PF02434.16 ORY45163.1 - 0.00011 21.8 0.0 0.0004 19.9 0.0 1.8 2 0 0 2 2 2 1 Fringe-like PAN_4 PF14295.6 ORY45163.1 - 0.0059 16.5 0.2 0.013 15.3 0.2 1.6 1 0 0 1 1 1 1 PAN domain Fringe PF02434.16 ORY45164.1 - 4.3e-10 39.5 0.0 2.4e-09 37.0 0.0 2.1 2 1 0 2 2 2 1 Fringe-like DUF604 PF04646.12 ORY45164.1 - 3.8e-08 33.0 0.0 7.1e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 PAN_1 PF00024.26 ORY45164.1 - 5.8e-06 26.2 0.1 1e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 PAN domain Galactosyl_T PF01762.21 ORY45164.1 - 7.5e-06 25.9 0.0 1.9e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 Galactosyltransferase PAN_4 PF14295.6 ORY45164.1 - 2.4e-05 24.2 0.5 5.4e-05 23.0 0.5 1.6 1 0 0 1 1 1 1 PAN domain RCC1_2 PF13540.6 ORY45164.1 - 0.13 12.1 0.3 0.43 10.5 0.3 1.8 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat Fringe PF02434.16 ORY45165.1 - 1.6e-08 34.3 0.7 2.2e-08 33.8 0.1 1.6 2 0 0 2 2 2 1 Fringe-like DUF604 PF04646.12 ORY45165.1 - 2.3e-07 30.5 0.2 4.9e-07 29.4 0.1 1.5 1 1 1 2 2 2 1 Protein of unknown function, DUF604 Galactosyl_T PF01762.21 ORY45165.1 - 1e-05 25.4 0.0 2.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Galactosyltransferase TauD PF02668.16 ORY45166.1 - 6.2e-47 160.6 0.2 8.2e-47 160.2 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TauD PF02668.16 ORY45167.1 - 6.3e-40 137.7 0.5 1e-39 136.9 0.5 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_transf_34 PF05637.12 ORY45168.1 - 9.3e-14 51.7 1.5 4.2e-08 33.2 0.5 2.2 1 1 1 2 2 2 2 galactosyl transferase GMA12/MNN10 family CH PF00307.31 ORY45169.1 - 0.0013 18.9 0.0 0.0048 17.1 0.0 2.0 1 0 0 1 1 1 1 Calponin homology (CH) domain SelP_N PF04592.14 ORY45169.1 - 0.74 9.2 11.7 1.9 7.8 11.7 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Atg14 PF10186.9 ORY45171.1 - 0.00021 20.5 28.9 0.025 13.7 19.3 2.3 1 1 1 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 CLZ PF16526.5 ORY45171.1 - 0.00063 20.1 6.6 0.00063 20.1 6.6 3.7 2 2 3 5 5 5 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels WXG100 PF06013.12 ORY45171.1 - 0.0054 16.9 0.7 2.1 8.6 0.3 2.7 2 0 0 2 2 2 1 Proteins of 100 residues with WXG HlyD_2 PF12700.7 ORY45171.1 - 0.0082 14.9 2.8 0.0082 14.9 2.8 2.4 1 1 1 2 2 2 1 HlyD family secretion protein KASH_CCD PF14662.6 ORY45171.1 - 0.045 13.6 37.7 0.65 9.8 10.3 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH CP12 PF02672.15 ORY45171.1 - 0.098 13.4 0.5 0.098 13.4 0.5 3.4 3 1 1 4 4 4 0 CP12 domain DUF2968 PF11180.8 ORY45171.1 - 0.59 9.7 21.5 0.026 14.2 8.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF812 PF05667.11 ORY45171.1 - 0.63 8.8 27.9 0.9 8.3 27.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Tropomyosin_1 PF12718.7 ORY45171.1 - 0.98 9.6 36.8 0.81 9.8 25.5 2.5 2 1 0 2 2 2 0 Tropomyosin like Fez1 PF06818.15 ORY45171.1 - 1 9.8 33.6 0.75 10.2 29.7 2.4 1 1 2 3 3 3 0 Fez1 CENP-H PF05837.12 ORY45171.1 - 4 7.9 34.8 0.37 11.2 16.8 3.4 1 1 3 4 4 4 0 Centromere protein H (CENP-H) DUF4407 PF14362.6 ORY45171.1 - 5.4 6.3 26.9 5.5 6.2 19.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4055 PF13264.6 ORY45171.1 - 6.5 6.9 9.2 1.1 9.4 2.8 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4055) HIP1_clath_bdg PF16515.5 ORY45171.1 - 6.8 7.4 34.3 4.6 7.9 2.3 3.5 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 GAS PF13851.6 ORY45171.1 - 7.7 5.8 33.6 3.3 7.0 28.5 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ERG4_ERG24 PF01222.17 ORY45172.1 - 1.1e-45 156.2 16.4 5.8e-45 153.8 16.4 1.9 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 ORY45172.1 - 0.00023 20.8 1.1 0.00091 18.8 1.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) NAD_binding_4 PF07993.12 ORY45173.1 - 1.7e-10 40.5 0.0 1.9e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 ORY45174.1 - 1.1e-28 100.0 0.0 1.7e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 ORY45174.1 - 2.2e-08 34.3 0.0 6.6e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site NAD_binding_4 PF07993.12 ORY45174.1 - 3.8e-07 29.5 0.0 5.8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein DUF2072 PF09845.9 ORY45174.1 - 0.13 12.5 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein DUF3454 PF11936.8 ORY45174.1 - 0.14 12.6 0.2 2.4 8.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3454) ScsC_N PF18312.1 ORY45174.1 - 0.24 11.2 0.8 7.1 6.5 0.9 2.4 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain AMP-binding PF00501.28 ORY45175.1 - 1.7e-15 56.5 0.1 1.9e-15 56.4 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme adh_short PF00106.25 ORY45176.1 - 9e-11 41.6 0.9 1.2e-10 41.2 0.2 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY45176.1 - 0.00018 21.1 0.0 0.00031 20.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY45176.1 - 0.0024 17.8 0.1 0.014 15.4 0.0 1.9 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.20 ORY45176.1 - 0.023 14.7 0.5 0.068 13.2 0.1 1.8 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.6 ORY45176.1 - 0.061 12.6 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase LRR_8 PF13855.6 ORY45177.1 - 4.4e-11 42.4 41.4 5.4e-05 22.9 3.8 5.9 2 1 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 ORY45177.1 - 1.1e-07 32.1 35.7 0.045 14.2 2.0 7.2 3 1 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY45177.1 - 0.0014 18.9 39.1 0.55 11.0 0.6 9.8 5 3 3 8 8 8 4 Leucine Rich Repeat CENP-B_dimeris PF09026.10 ORY45179.1 - 0.034 14.5 2.7 0.074 13.5 2.7 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 ORY45179.1 - 0.61 9.3 7.3 1 8.7 7.3 1.2 1 0 0 1 1 1 0 NOA36 protein TLP-20 PF06088.11 ORY45179.1 - 2.5 7.9 6.8 0.56 10.1 3.2 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Casc1 PF12366.8 ORY45180.1 - 0.013 15.0 5.0 0.04 13.4 5.0 1.8 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 STE3 PF02076.15 ORY45182.1 - 0.004 16.4 4.3 0.0061 15.8 4.3 1.3 1 0 0 1 1 1 1 Pheromone A receptor Peptidase_C30 PF05409.13 ORY45182.1 - 0.01 15.1 0.1 0.017 14.4 0.1 1.4 1 0 0 1 1 1 0 Coronavirus endopeptidase C30 2OG-FeII_Oxy_2 PF13532.6 ORY45183.1 - 3.9e-14 53.3 0.0 4.5e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.32 ORY45184.1 - 2.8e-07 31.1 9.8 0.051 14.5 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat NTP_transf_9 PF04248.12 ORY45184.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF427) CPSF_A PF03178.15 ORY45184.1 - 0.074 12.3 0.1 1 8.6 0.0 2.4 1 1 1 2 2 2 0 CPSF A subunit region PgaPase_1 PF06162.12 ORY45184.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative pyroglutamyl peptidase PgaPase_1 OMS28_porin PF03532.13 ORY45184.1 - 0.22 10.7 0.5 0.31 10.2 0.5 1.2 1 0 0 1 1 1 0 OMS28 porin SET PF00856.28 ORY45185.1 - 3.1e-11 43.9 0.1 2.6e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 SET domain SKA2 PF16740.5 ORY45185.1 - 0.017 14.9 0.7 0.17 11.6 0.2 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF948 PF06103.11 ORY45185.1 - 0.11 12.8 0.1 7.4 6.9 0.3 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Herpes_UL25 PF01499.16 ORY45185.1 - 0.19 10.2 1.0 0.27 9.7 1.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Cyclin_N PF00134.23 ORY45188.1 - 0.022 14.5 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Cyclin PF08613.11 ORY45188.1 - 0.028 14.8 0.0 0.056 13.8 0.0 1.5 1 1 0 1 1 1 0 Cyclin Cyclin_N PF00134.23 ORY45189.1 - 5.4e-06 26.2 0.5 9.5e-06 25.4 0.5 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORY45189.1 - 0.0023 18.3 0.6 0.0023 18.3 0.6 2.1 2 0 0 2 2 2 1 Cyclin DUF1765 PF08578.10 ORY45189.1 - 0.096 13.2 1.3 0.2 12.1 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1765) Cyclin_N PF00134.23 ORY45190.1 - 4.3e-06 26.5 0.1 8.1e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORY45190.1 - 0.0004 20.8 6.7 0.0017 18.8 0.6 2.1 2 0 0 2 2 2 2 Cyclin Cyclin_N PF00134.23 ORY45191.1 - 1.5e-07 31.2 1.7 2.2e-07 30.7 1.4 1.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORY45191.1 - 0.0008 19.8 0.2 0.0011 19.4 0.2 1.2 1 0 0 1 1 1 1 Cyclin BtrH_N PF14399.6 ORY45191.1 - 0.069 13.4 0.0 0.34 11.2 0.0 1.9 1 1 1 2 2 2 0 Butirosin biosynthesis protein H, N-terminal FNIP_M PF14637.6 ORY45191.1 - 0.19 11.7 3.4 3.9 7.4 0.8 2.1 1 1 1 2 2 2 0 Folliculin-interacting protein middle domain Cyclin_N PF00134.23 ORY45192.1 - 0.00035 20.3 0.6 0.001 18.8 0.5 1.8 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORY45192.1 - 0.013 15.9 0.1 0.019 15.3 0.1 1.3 1 0 0 1 1 1 0 Cyclin Cyclin_N PF00134.23 ORY45193.1 - 1.7e-13 50.4 0.0 2.7e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORY45193.1 - 0.0061 16.9 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin GTP_cyclohydroI PF01227.22 ORY45194.1 - 3.6e-75 251.3 0.1 4.6e-75 251.0 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 ORY45194.1 - 0.0013 18.8 0.2 0.004 17.3 0.0 1.9 3 0 0 3 3 3 1 QueF-like protein EIF_2_alpha PF07541.12 ORY45194.1 - 0.02 15.0 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit TIM PF00121.18 ORY45194.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Triosephosphate isomerase AKAP7_NLS PF10469.9 ORY45195.1 - 9.7e-24 84.4 0.0 8.6e-23 81.3 0.0 1.9 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 ORY45195.1 - 2.3e-10 40.6 0.0 2.8e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 ORY45195.1 - 0.0028 17.8 0.0 0.55 10.5 0.0 2.8 2 1 0 2 2 2 1 LigT like Phosphoesterase EF-hand_6 PF13405.6 ORY45196.1 - 0.0001 22.0 0.6 0.00025 20.7 0.6 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 ORY45196.1 - 0.0057 16.1 0.1 0.015 14.8 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 ORY45196.1 - 0.023 15.1 0.2 0.045 14.2 0.2 1.5 1 0 0 1 1 1 0 EF-hand domain pair CALCOCO1 PF07888.11 ORY45196.1 - 0.1 11.5 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ANAPC4_WD40 PF12894.7 ORY45197.1 - 1.8e-07 31.4 0.2 0.0065 16.7 0.0 3.9 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY45197.1 - 6.6e-07 29.9 5.3 0.048 14.5 0.0 4.6 4 1 1 5 5 5 2 WD domain, G-beta repeat Proteasome_A_N PF10584.9 ORY45197.1 - 0.0041 16.8 0.7 1.3 8.8 0.0 3.4 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature DPPIV_N PF00930.21 ORY45197.1 - 0.006 15.4 0.6 5.5 5.6 0.0 3.5 3 1 0 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.11 ORY45197.1 - 0.0083 16.0 0.0 0.16 11.8 0.0 2.4 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 ORY45197.1 - 0.013 15.4 3.4 0.25 11.3 0.1 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat IKI3 PF04762.12 ORY45197.1 - 0.028 12.4 0.7 1.5 6.7 0.0 2.1 2 0 0 2 2 2 0 IKI3 family Phytase-like PF13449.6 ORY45197.1 - 0.2 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Esterase-like activity of phytase SecE PF00584.20 ORY45199.1 - 1.7 8.6 6.1 38 4.3 0.6 4.6 2 0 0 2 2 2 0 SecE/Sec61-gamma subunits of protein translocation complex Amino_oxidase PF01593.24 ORY45201.1 - 0.00084 18.7 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DEAD PF00270.29 ORY45202.1 - 3.7e-19 69.1 0.2 8.3e-19 68.0 0.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY45202.1 - 1.3e-15 57.7 0.1 3.7e-15 56.2 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4410 PF14366.6 ORY45202.1 - 0.034 14.1 1.4 0.11 12.4 1.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) BUD22 PF09073.10 ORY45202.1 - 0.94 8.8 30.3 1.8 7.8 30.3 1.4 1 0 0 1 1 1 0 BUD22 DUF659 PF04937.15 ORY45203.1 - 1.7e-08 34.5 0.0 2.6e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Filament_head PF04732.14 ORY45204.1 - 0.28 12.1 5.6 0.63 11.0 5.6 1.6 1 0 0 1 1 1 0 Intermediate filament head (DNA binding) region KptA_kDCL PF18176.1 ORY45205.1 - 0.11 12.3 0.1 7.8 6.3 0.0 2.3 2 0 0 2 2 2 0 KptA in kinetoplastid DICER domain Syntaxin PF00804.25 ORY45206.1 - 2.3e-19 69.9 14.1 4.1e-19 69.1 14.1 1.4 1 1 0 1 1 1 1 Syntaxin Goodbye PF17109.5 ORY45206.1 - 0.038 14.5 0.4 0.57 10.6 0.0 2.6 2 1 0 2 2 2 0 fungal STAND N-terminal Goodbye domain PriC PF07445.12 ORY45206.1 - 0.084 12.8 10.6 0.088 12.7 5.1 2.5 1 1 0 2 2 2 0 Primosomal replication protein priC 4HB_MCP_1 PF12729.7 ORY45206.1 - 0.1 12.2 6.9 0.25 10.9 1.3 2.4 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction Syntaxin_2 PF14523.6 ORY45206.1 - 0.32 11.4 15.4 0.54 10.7 7.4 2.5 2 0 0 2 2 2 0 Syntaxin-like protein LMBR1 PF04791.16 ORY45206.1 - 0.54 9.1 4.0 0.85 8.5 4.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-C4H2 PF10146.9 ORY45206.1 - 3.4 7.9 7.7 1.6 9.0 3.8 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein Glyco_hydro_20 PF00728.22 ORY45207.1 - 4.6e-74 249.9 0.0 6.3e-74 249.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY45207.1 - 7e-09 36.5 0.3 1e-07 32.7 0.3 2.2 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY45207.1 - 3.9e-08 34.1 0.0 8.5e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 KH_1 PF00013.29 ORY45208.1 - 1.3e-18 66.6 0.0 7e-08 32.2 0.0 3.6 3 0 0 3 3 3 3 KH domain Clr2_transil PF16761.5 ORY45208.1 - 1.1e-17 64.6 1.3 2.7e-17 63.3 1.3 1.7 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 TAF8_C PF10406.9 ORY45208.1 - 0.0083 16.7 0.3 0.0083 16.7 0.3 3.3 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term WD40 PF00400.32 ORY45210.1 - 3.8e-15 56.0 5.8 0.04 14.8 0.0 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY45210.1 - 6.3e-11 42.4 0.0 0.0093 16.3 0.0 5.5 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY45210.1 - 0.00043 19.3 0.1 0.73 8.7 0.0 3.4 3 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ORY45210.1 - 0.00051 19.5 0.1 0.016 14.6 0.0 2.4 1 1 2 3 3 3 1 WD40-like domain Lactonase PF10282.9 ORY45210.1 - 0.0039 16.5 0.0 0.018 14.3 0.0 1.8 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Nop14 PF04147.12 ORY45210.1 - 0.047 11.9 32.8 0.064 11.5 32.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 ORY45210.1 - 0.052 11.8 25.9 0.082 11.2 25.9 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 ORY45210.1 - 1.3 8.8 10.7 2.5 7.8 10.7 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SAPS PF04499.15 ORY45210.1 - 1.5 7.5 11.9 1.9 7.2 11.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 ORY45210.1 - 1.7 8.0 39.0 2.6 7.4 39.0 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 ORY45210.1 - 2.7 7.2 38.7 3.9 6.7 38.7 1.1 1 0 0 1 1 1 0 BUD22 Hid1 PF12722.7 ORY45210.1 - 2.7 6.0 9.4 3.6 5.6 9.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SURF2 PF05477.11 ORY45210.1 - 6.2 6.4 20.6 11 5.6 20.6 1.4 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) UCH PF00443.29 ORY45211.1 - 8.9e-48 163.0 0.0 1.1e-47 162.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY45211.1 - 5e-13 49.3 0.4 1.7e-12 47.6 0.4 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 ORY45211.1 - 4e-08 32.9 0.1 1.1e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family Peptidase_C98 PF15499.6 ORY45211.1 - 0.036 13.5 0.1 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase MFS_1 PF07690.16 ORY45215.1 - 3.3e-34 118.4 52.9 1.8e-31 109.3 25.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY45215.1 - 8.5e-12 44.7 7.6 8.5e-12 44.7 7.6 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 ORY45215.1 - 3.5e-05 23.3 3.0 9e-05 21.9 3.0 1.6 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 ORY45215.1 - 0.00057 18.9 18.8 0.023 13.6 0.1 3.4 2 1 1 3 3 3 2 MFS_1 like family TRI12 PF06609.13 ORY45215.1 - 0.0029 16.1 1.7 0.0059 15.1 1.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2207 PF09972.9 ORY45215.1 - 0.014 14.2 4.0 6.2 5.5 1.5 3.1 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) MFS_3 PF05977.13 ORY45215.1 - 0.023 13.1 7.3 0.6 8.4 1.7 2.4 2 1 0 2 2 2 0 Transmembrane secretion effector DUF3311 PF11755.8 ORY45215.1 - 0.15 12.0 5.5 0.099 12.6 3.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) Phage_holin_2_4 PF16082.5 ORY45215.1 - 0.16 11.7 0.0 2.8 7.7 0.0 2.6 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like LRR_6 PF13516.6 ORY45216.1 - 1.2e-14 53.0 10.2 4.7e-06 26.2 0.0 6.3 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 ORY45216.1 - 0.0013 19.0 0.6 41 5.3 0.0 4.9 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_4 PF12799.7 ORY45216.1 - 0.63 10.5 11.2 3 8.4 0.1 3.9 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Elf1 PF05129.13 ORY45217.1 - 8.6e-27 93.0 2.5 9.5e-27 92.9 2.5 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Ribosomal_L37ae PF01780.19 ORY45217.1 - 0.0086 16.1 1.8 0.013 15.6 1.8 1.2 1 1 0 1 1 1 1 Ribosomal L37ae protein family GATA PF00320.27 ORY45217.1 - 0.017 14.7 0.1 0.031 13.9 0.1 1.5 1 1 0 1 1 1 0 GATA zinc finger Zn-ribbon_8 PF09723.10 ORY45217.1 - 0.019 15.1 1.8 0.056 13.6 1.8 1.7 1 1 1 2 2 2 0 Zinc ribbon domain A2L_zn_ribbon PF08792.10 ORY45217.1 - 0.021 14.5 4.8 0.056 13.2 4.8 1.7 1 1 0 1 1 1 0 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.7 ORY45217.1 - 0.023 14.7 0.2 0.03 14.3 0.2 1.2 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF2387 PF09526.10 ORY45217.1 - 0.024 14.8 0.8 0.04 14.1 0.8 1.4 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Vps36-NZF-N PF16988.5 ORY45217.1 - 0.025 13.9 0.3 0.043 13.2 0.3 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain LIM PF00412.22 ORY45217.1 - 0.061 13.6 4.1 1.7 8.9 3.9 2.1 1 1 0 1 1 1 0 LIM domain zf-C2HE PF16278.5 ORY45217.1 - 0.063 13.7 6.2 0.31 11.5 1.0 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf_UBZ PF18439.1 ORY45217.1 - 0.081 12.5 2.0 1.2 8.7 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zinc_ribbon_15 PF17032.5 ORY45217.1 - 0.11 13.2 3.7 0.16 12.7 3.7 1.4 1 1 0 1 1 1 0 zinc-ribbon family zf-H2C2_2 PF13465.6 ORY45217.1 - 0.11 12.9 1.8 9 6.9 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain DNA_RNApol_7kD PF03604.13 ORY45217.1 - 0.46 10.2 4.3 3.5 7.4 4.3 2.1 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit DUF1451 PF07295.11 ORY45217.1 - 2 8.5 6.3 8.4 6.4 0.5 2.1 1 1 1 2 2 2 0 Zinc-ribbon containing domain MIG-14_Wnt-bd PF06664.12 ORY45218.1 - 0.33 10.1 5.0 0.43 9.8 4.5 1.4 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion AA_kinase PF00696.28 ORY45219.1 - 9.4e-26 90.9 0.0 1.6e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 ORY45219.1 - 3e-10 39.7 0.2 0.00048 19.8 0.0 2.6 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 ORY45219.1 - 1.3e-08 34.5 2.3 3e-05 23.7 0.3 2.4 2 0 0 2 2 2 2 ACT domain zf-CCHC PF00098.23 ORY45220.1 - 4.2e-07 29.7 3.9 7.8e-07 28.9 3.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 ORY45220.1 - 0.038 13.7 2.1 0.079 12.7 1.4 1.8 2 0 0 2 2 2 0 Zinc knuckle AA_kinase PF00696.28 ORY45221.1 - 4.4e-13 49.4 0.2 5.8e-13 49.0 0.2 1.1 1 0 0 1 1 1 1 Amino acid kinase family Thymidylate_kin PF02223.17 ORY45221.1 - 0.0036 17.0 0.0 0.0049 16.6 0.0 1.2 1 0 0 1 1 1 1 Thymidylate kinase Peptidase_C23 PF05379.11 ORY45221.1 - 0.0073 16.4 0.4 0.41 10.8 0.0 2.8 2 1 1 3 3 3 1 Carlavirus endopeptidase zf-CCHH PF10283.9 ORY45222.1 - 1.5e-13 50.4 1.1 2.5e-13 49.7 1.1 1.3 1 0 0 1 1 1 1 PBZ domain GFP PF01353.22 ORY45222.1 - 0.046 13.2 0.0 0.069 12.6 0.0 1.2 1 0 0 1 1 1 0 Green fluorescent protein DNA_ligase_OB_2 PF14743.6 ORY45223.1 - 2e-29 101.4 0.2 4.3e-29 100.3 0.2 1.6 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 ORY45223.1 - 8e-13 48.5 0.0 1.3e-11 44.6 0.0 2.2 1 1 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.10 ORY45223.1 - 2.8e-05 24.5 0.0 9.3e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 RNA ligase zf-C2HC5 PF06221.13 ORY45225.1 - 9.2e-12 44.8 7.7 1.5e-11 44.1 7.7 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type TerY_C PF15616.6 ORY45225.1 - 0.14 12.3 2.9 0.28 11.3 2.9 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain DUF5427 PF10310.9 ORY45225.1 - 1.3 7.9 11.0 2.3 7.1 11.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5427) ARF7EP_C PF14949.6 ORY45225.1 - 9.2 6.9 10.0 0.35 11.5 1.9 2.6 2 1 1 3 3 3 0 ARF7 effector protein C-terminus Costars PF14705.6 ORY45227.1 - 8e-24 83.6 0.2 9.2e-24 83.4 0.2 1.0 1 0 0 1 1 1 1 Costars Glyco_transf_34 PF05637.12 ORY45228.1 - 2.1e-16 60.4 1.0 3.1e-14 53.3 1.0 2.3 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family BAR_2 PF10455.9 ORY45229.1 - 1e-44 152.8 1.2 1.1e-42 146.2 1.2 2.0 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 ORY45229.1 - 5.2e-18 65.6 0.1 7.6e-18 65.0 0.1 1.2 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.13 ORY45229.1 - 1.1e-06 28.4 1.7 2.3e-06 27.4 0.4 2.1 2 1 0 2 2 2 1 Arfaptin-like domain BAR_3 PF16746.5 ORY45229.1 - 4.5e-06 26.5 0.6 1.1e-05 25.3 0.1 1.7 2 0 0 2 2 2 1 BAR domain of APPL family CAF-1_p60_C PF15512.6 ORY45229.1 - 0.012 16.1 0.4 0.018 15.6 0.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor complex 1 subunit p60, C-terminal FGase PF05013.12 ORY45229.1 - 0.037 14.2 0.1 0.054 13.7 0.1 1.3 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase GH131_N PF18271.1 ORY45229.1 - 0.06 13.0 0.0 0.091 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 131 catalytic N-terminal domain Laminin_II PF06009.12 ORY45229.1 - 0.083 12.9 0.5 2.6 8.0 0.0 2.8 2 2 1 3 3 3 0 Laminin Domain II Phasin PF05597.11 ORY45229.1 - 0.31 11.1 1.6 1.1 9.3 0.6 2.4 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Ribosomal_L37e PF01907.19 ORY45230.1 - 2.3e-26 91.7 12.8 2.3e-26 91.7 12.8 1.5 2 0 0 2 2 2 1 Ribosomal protein L37e zf-RING_2 PF13639.6 ORY45232.1 - 9.5e-13 48.3 3.2 1.7e-12 47.5 3.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORY45232.1 - 4.6e-09 36.0 2.5 7.7e-09 35.3 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY45232.1 - 6.3e-09 36.0 2.4 1.3e-08 35.0 2.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORY45232.1 - 1.1e-06 28.4 5.5 4.2e-06 26.5 5.5 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY45232.1 - 1.4e-06 28.2 1.3 2.8e-06 27.3 1.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 ORY45232.1 - 3.7e-06 26.6 5.7 3.7e-06 26.6 5.7 1.7 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 ORY45232.1 - 7.9e-06 25.7 3.5 1.3e-05 25.0 3.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 ORY45232.1 - 0.00014 21.8 2.8 0.00038 20.5 2.8 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 ORY45232.1 - 0.00026 20.8 2.8 0.00046 20.0 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 ORY45232.1 - 0.00077 19.6 4.3 0.0019 18.3 4.3 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 ORY45232.1 - 0.0038 17.4 0.7 0.0038 17.4 0.7 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING RINGv PF12906.7 ORY45232.1 - 0.022 14.8 4.8 0.022 14.8 4.8 1.8 2 0 0 2 2 1 0 RING-variant domain Zf_RING PF16744.5 ORY45232.1 - 0.08 13.1 2.1 0.15 12.2 2.1 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger FYVE PF01363.21 ORY45232.1 - 0.09 12.9 2.8 0.15 12.2 2.8 1.4 1 0 0 1 1 1 0 FYVE zinc finger zf-RING-like PF08746.11 ORY45232.1 - 0.12 12.7 4.5 0.25 11.7 4.5 1.6 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 ORY45232.1 - 0.13 12.2 4.2 0.22 11.5 4.2 1.4 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 ORY45232.1 - 0.18 11.7 3.8 0.34 10.8 3.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 NMO PF03060.15 ORY45234.1 - 8e-61 206.2 0.5 1e-60 205.9 0.5 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ORY45234.1 - 3.7e-11 42.6 3.8 1.8e-10 40.4 3.8 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 ORY45234.1 - 8.4e-07 28.3 2.5 1.4e-06 27.6 2.5 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 ORY45234.1 - 0.031 13.4 3.1 0.065 12.4 3.1 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase Dus PF01207.17 ORY45235.1 - 1.4e-41 142.6 0.0 4.1e-40 137.8 0.0 2.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Syntaxin PF00804.25 ORY45236.1 - 3.9e-17 62.6 9.6 7.5e-17 61.7 9.6 1.5 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 ORY45236.1 - 2.3e-10 40.3 0.6 2.3e-10 40.3 0.6 2.8 3 0 0 3 3 3 1 SNARE domain LMBR1 PF04791.16 ORY45236.1 - 0.011 14.7 6.1 0.016 14.1 6.1 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Complex1_LYR_2 PF13233.6 ORY45236.1 - 0.074 13.8 0.6 0.46 11.3 0.0 2.2 1 1 1 2 2 2 0 Complex1_LYR-like Fib_alpha PF08702.10 ORY45236.1 - 0.11 12.7 13.9 0.52 10.5 2.5 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family MnmE_helical PF12631.7 ORY45236.1 - 0.44 10.7 5.2 0.63 10.2 5.2 1.2 1 0 0 1 1 1 0 MnmE helical domain Syntaxin_2 PF14523.6 ORY45236.1 - 0.73 10.2 8.7 0.45 10.9 2.7 2.5 2 1 0 2 2 2 0 Syntaxin-like protein Vpu PF00558.19 ORY45236.1 - 1.3 8.9 9.2 0.81 9.5 6.1 2.3 2 0 0 2 2 2 0 Vpu protein Bacillus_HBL PF05791.11 ORY45236.1 - 1.4 8.7 10.3 2.2 8.1 1.0 2.3 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Muted PF14942.6 ORY45236.1 - 3.4 8.0 10.4 2.3 8.5 2.5 2.4 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein PCRF PF03462.18 ORY45236.1 - 8 6.3 9.0 0.86 9.4 2.4 2.3 1 1 0 2 2 2 0 PCRF domain 7tm_1 PF00001.21 ORY45237.1 - 0.027 13.8 0.1 0.033 13.5 0.1 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 ORY45238.1 - 3.9e-09 36.2 15.4 4.7e-09 35.9 15.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Git3 PF11710.8 ORY45238.1 - 0.0006 19.6 15.1 0.0011 18.8 15.1 1.4 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 SPA PF08616.10 ORY45238.1 - 0.035 14.1 0.2 0.075 13.0 0.2 1.6 1 1 0 1 1 1 0 Stabilization of polarity axis DUF2457 PF10446.9 ORY45239.1 - 0.081 12.1 9.7 0.089 11.9 9.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.13 ORY45239.1 - 0.67 8.0 6.5 0.8 7.7 6.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 ORY45239.1 - 4.4 6.6 10.5 4.9 6.4 10.5 1.1 1 0 0 1 1 1 0 NOA36 protein zf_CCCH_4 PF18345.1 ORY45240.1 - 1.3e-11 44.2 29.8 8.1e-07 28.9 1.3 4.5 4 0 0 4 4 4 3 Zinc finger domain Torus PF16131.5 ORY45240.1 - 2.2e-10 41.2 12.9 3.4e-07 30.9 0.1 3.2 3 1 1 4 4 3 2 Torus domain zf-C3HC4 PF00097.25 ORY45240.1 - 4.8e-08 32.7 4.8 2.6e-07 30.4 4.8 2.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.24 ORY45240.1 - 9.2e-08 31.8 17.6 0.00036 20.4 3.4 3.9 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 ORY45240.1 - 2.7e-06 27.2 5.5 2.7e-06 27.2 5.5 3.1 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY45240.1 - 2.7e-06 27.3 1.0 2.7e-06 27.3 1.0 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY45240.1 - 3.8e-06 26.8 4.1 3.8e-06 26.8 4.1 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 ORY45240.1 - 7.4e-06 26.2 4.2 7.4e-06 26.2 4.2 2.7 2 0 0 2 2 2 1 Ring finger domain zf-CCCH_3 PF15663.5 ORY45240.1 - 4.2e-05 23.7 10.9 0.027 14.7 1.6 3.2 2 1 1 3 3 3 2 Zinc-finger containing family zf-C3HC4_2 PF13923.6 ORY45240.1 - 0.0003 20.5 1.4 0.0003 20.5 1.4 3.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.6 ORY45240.1 - 0.0012 19.3 23.2 0.37 11.3 2.7 4.0 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 ORY45240.1 - 0.0016 18.2 20.3 0.0049 16.6 3.4 3.9 3 1 0 3 3 3 2 CCCH-type zinc finger Zn_ribbon_17 PF17120.5 ORY45240.1 - 0.026 14.1 0.6 0.026 14.1 0.6 2.9 4 0 0 4 4 4 0 Zinc-ribbon, C4HC2 type zf-C3HC4_4 PF15227.6 ORY45240.1 - 0.034 14.3 5.3 0.18 12.0 5.3 2.4 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF4789 PF16033.5 ORY45240.1 - 0.064 13.8 4.6 0.28 11.7 4.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4789) Prok-RING_4 PF14447.6 ORY45240.1 - 0.099 12.5 10.7 0.034 14.0 4.3 3.3 2 2 0 2 2 2 0 Prokaryotic RING finger family 4 TFIIA PF03153.13 ORY45241.1 - 0.0051 16.9 31.5 0.0064 16.5 31.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 ORY45241.1 - 0.01 16.3 4.8 0.011 16.1 4.8 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Ndc1_Nup PF09531.10 ORY45241.1 - 0.066 11.9 10.0 0.073 11.8 10.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 ORY45241.1 - 0.15 10.8 10.3 0.18 10.5 10.3 1.1 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 ORY45241.1 - 0.34 10.9 14.2 0.42 10.6 14.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) GREB1 PF15782.5 ORY45241.1 - 0.59 7.2 11.6 0.68 7.0 11.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Endostatin PF06482.11 ORY45241.1 - 1.4 8.3 10.3 1.8 8.0 10.3 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin TERB2 PF15101.6 ORY45241.1 - 1.7 8.7 11.7 2.4 8.2 11.7 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SprA-related PF12118.8 ORY45241.1 - 2.2 7.4 23.3 3 6.9 23.3 1.2 1 0 0 1 1 1 0 SprA-related family Lin-8 PF03353.15 ORY45241.1 - 2.6 7.5 15.2 3.1 7.3 15.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ECM1 PF05782.11 ORY45241.1 - 3.3 6.5 18.9 3.9 6.3 18.9 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) SAGA-Tad1 PF12767.7 ORY45241.1 - 4.1 7.1 13.2 5.6 6.6 13.2 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit ALMT PF11744.8 ORY45241.1 - 6.7 5.4 8.0 8.5 5.1 8.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Roughex PF06020.11 ORY45241.1 - 9 5.3 12.0 12 4.9 12.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein HMG_box PF00505.19 ORY45243.1 - 6.7e-05 23.2 0.2 0.00042 20.7 0.2 2.1 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY45243.1 - 0.034 14.7 0.0 0.083 13.5 0.0 1.6 1 0 0 1 1 1 0 HMG-box domain EF-1_beta_acid PF10587.9 ORY45244.1 - 0.024 15.1 3.1 0.024 15.1 3.1 2.8 3 1 1 4 4 4 0 Eukaryotic elongation factor 1 beta central acidic region VEK-30 PF12107.8 ORY45244.1 - 0.24 11.3 3.7 0.61 10.1 3.7 1.7 1 0 0 1 1 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway DUF3328 PF11807.8 ORY45244.1 - 1.4 8.6 3.5 0.45 10.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) FAA_hydrolase PF01557.18 ORY45245.1 - 1.5e-58 198.0 0.0 1.9e-58 197.7 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family XPG_I PF00867.18 ORY45246.1 - 2.2e-17 63.2 1.5 1.3e-15 57.5 0.1 2.9 2 1 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 ORY45246.1 - 4.3e-06 27.3 0.4 4.3e-05 24.0 0.0 2.5 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 ORY45246.1 - 0.0067 16.5 0.0 0.022 14.8 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif MHYT PF03707.16 ORY45247.1 - 1.1e-16 60.8 16.1 1.7e-11 44.1 7.3 2.6 2 1 0 2 2 2 2 Bacterial signalling protein N terminal repeat Proton_antipo_M PF00361.20 ORY45247.1 - 0.015 14.5 3.7 0.021 14.0 3.7 1.1 1 0 0 1 1 1 0 Proton-conducting membrane transporter ATP-synt_J PF04911.12 ORY45247.1 - 2.7 7.6 5.0 0.83 9.3 1.5 2.0 2 0 0 2 2 2 0 ATP synthase j chain UPF0016 PF01169.19 ORY45247.1 - 3 8.2 7.2 18 5.8 6.9 2.1 1 1 1 2 2 2 0 Uncharacterized protein family UPF0016 FAD_binding_3 PF01494.19 ORY45249.1 - 1.2e-17 64.2 0.1 5.8e-10 39.0 0.0 2.7 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 ORY45249.1 - 1.3e-07 31.6 0.6 0.00038 20.1 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY45249.1 - 0.00022 21.4 0.8 0.00052 20.2 0.8 1.8 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY45249.1 - 0.00056 19.2 0.1 0.0011 18.3 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY45249.1 - 0.0034 17.9 0.4 0.0064 17.0 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ORY45249.1 - 0.0059 15.9 0.2 0.022 14.1 0.1 1.9 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 ORY45249.1 - 0.0097 15.2 0.3 0.016 14.5 0.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 ORY45249.1 - 0.016 14.3 0.0 0.091 11.8 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain SE PF08491.10 ORY45249.1 - 0.041 12.9 0.0 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase GIDA PF01134.22 ORY45249.1 - 0.062 12.4 0.2 0.089 11.9 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 ORY45249.1 - 0.064 12.6 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase WD40 PF00400.32 ORY45251.1 - 9.1e-27 92.8 10.9 8.7e-05 23.2 0.0 6.7 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY45251.1 - 2.6e-10 40.4 4.5 3.1e-06 27.4 0.2 3.8 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY45251.1 - 3.7e-08 33.5 0.6 0.0038 17.1 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A ELYS-bb PF16687.5 ORY45251.1 - 0.026 13.1 0.0 0.078 11.6 0.0 1.7 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin LRR_8 PF13855.6 ORY45252.1 - 5.3e-13 48.5 14.8 3.1e-06 26.8 2.6 4.2 3 1 1 4 4 4 3 Leucine rich repeat F-box PF00646.33 ORY45252.1 - 1.6e-06 27.8 0.4 1.6e-06 27.8 0.4 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 ORY45252.1 - 6.3e-05 22.8 2.8 9.4e-05 22.2 0.8 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.7 ORY45252.1 - 0.00012 22.3 19.3 0.062 13.7 0.7 5.0 3 1 2 5 5 4 3 Leucine Rich repeats (2 copies) PTRF_SDPR PF15237.6 ORY45252.1 - 0.0012 18.6 0.3 0.0018 18.0 0.3 1.2 1 0 0 1 1 1 1 PTRF/SDPR family Prominin PF05478.11 ORY45252.1 - 0.015 13.3 1.3 0.02 12.9 1.3 1.1 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.12 ORY45252.1 - 0.017 15.1 0.3 0.029 14.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) LRR_6 PF13516.6 ORY45252.1 - 0.026 14.6 7.6 27 5.2 0.4 5.1 4 0 0 4 4 4 0 Leucine Rich repeat FlaC_arch PF05377.11 ORY45252.1 - 0.033 14.6 0.4 0.075 13.4 0.4 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) V-SNARE PF05008.15 ORY45252.1 - 0.048 14.0 1.0 0.091 13.1 1.0 1.4 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus MutS_IV PF05190.18 ORY45252.1 - 0.054 13.8 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 MutS family domain IV Med9 PF07544.13 ORY45252.1 - 0.073 13.2 0.9 0.17 12.0 0.9 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 CLZ PF16526.5 ORY45252.1 - 0.078 13.3 0.2 0.21 12.0 0.2 1.8 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels LRR_1 PF00560.33 ORY45252.1 - 0.079 13.6 28.6 0.51 11.1 0.5 7.5 8 0 0 8 8 7 0 Leucine Rich Repeat Baculo_PEP_C PF04513.12 ORY45252.1 - 0.14 12.2 4.6 0.19 11.7 0.9 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Med4 PF10018.9 ORY45252.1 - 0.17 11.5 0.6 0.28 10.9 0.6 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 HSBP1 PF06825.12 ORY45252.1 - 0.18 11.7 2.5 1.1 9.1 1.0 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 LPP PF04728.13 ORY45252.1 - 0.2 12.1 1.6 0.49 10.8 1.6 1.6 1 0 0 1 1 1 0 Lipoprotein leucine-zipper LRR_4 PF12799.7 ORY45253.1 - 1.2e-05 25.5 32.6 0.013 15.9 3.9 5.4 5 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY45253.1 - 3.2e-05 23.6 38.0 0.022 14.5 2.8 4.7 3 2 0 4 4 4 3 Leucine rich repeat F-box PF00646.33 ORY45253.1 - 0.0045 16.8 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 F-box domain IFT57 PF10498.9 ORY45253.1 - 0.11 11.4 0.8 0.17 10.8 0.8 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 APG17 PF04108.12 ORY45253.1 - 0.11 11.5 0.5 0.2 10.7 0.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 GCR1_C PF12550.8 ORY45255.1 - 0.05 13.9 3.1 2.2 8.7 0.0 3.4 3 1 0 3 3 3 0 Transcriptional activator of glycolytic enzymes DUF3336 PF11815.8 ORY45255.1 - 0.6 9.8 3.1 1.9 8.2 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3336) DUF908 PF06012.12 ORY45256.1 - 2.1 7.7 5.7 3.8 6.8 5.7 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Ank_2 PF12796.7 ORY45258.1 - 4.3e-12 46.4 0.2 3.1e-05 24.5 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY45258.1 - 7.4e-11 42.1 0.7 6.3e-05 23.2 0.0 4.0 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY45258.1 - 8e-11 42.2 0.5 7e-05 23.3 0.3 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY45258.1 - 9.3e-11 41.7 4.0 0.0034 17.8 0.2 4.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 ORY45258.1 - 1.5e-08 34.2 0.9 0.085 13.5 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat KilA-N PF04383.13 ORY45259.1 - 3.8e-05 23.5 0.1 9.4e-05 22.2 0.1 1.7 1 1 0 1 1 1 1 KilA-N domain NRDE-2 PF08424.10 ORY45261.1 - 0.0006 19.0 1.1 0.0006 19.0 1.1 2.5 1 1 1 2 2 2 1 NRDE-2, necessary for RNA interference Glyco_transf_90 PF05686.12 ORY45262.1 - 1.3e-20 73.7 0.3 4.8e-10 38.9 0.0 2.1 1 1 0 2 2 2 2 Glycosyl transferase family 90 DUSP PF06337.12 ORY45263.1 - 4.4e-13 49.7 0.0 7.7e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 DUSP domain F-box-like PF12937.7 ORY45264.1 - 3.4e-05 23.6 0.4 6.6e-05 22.7 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORY45264.1 - 0.011 15.6 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 0 F-box F-box PF00646.33 ORY45264.1 - 0.045 13.7 1.1 0.22 11.5 1.1 2.1 1 1 0 1 1 1 0 F-box domain zf-UBP PF02148.19 ORY45265.1 - 1.7e-09 37.8 10.7 9.9e-09 35.4 10.7 2.2 1 1 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein F-box PF00646.33 ORY45265.1 - 0.0048 16.8 1.8 0.012 15.4 1.8 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY45265.1 - 0.016 15.1 1.2 0.037 13.9 1.2 1.7 1 0 0 1 1 1 0 F-box-like AA_permease_2 PF13520.6 ORY45266.1 - 6.8e-17 61.4 29.1 6.8e-10 38.3 11.7 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.21 ORY45266.1 - 5.8e-13 48.3 31.6 8e-12 44.5 12.0 2.2 2 0 0 2 2 2 2 Amino acid permease DUSP PF06337.12 ORY45267.1 - 6.6e-09 36.3 0.1 2.3e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 DUSP domain TB2_DP1_HVA22 PF03134.19 ORY45268.1 - 1.2e-07 31.6 5.4 2.1e-07 30.7 5.4 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family SF3A2 PF16835.5 ORY45269.1 - 1.4e-24 86.2 1.2 7e-22 77.6 1.2 2.3 1 1 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 ORY45269.1 - 5.7e-07 29.7 2.0 1.2e-06 28.6 2.0 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.11 ORY45269.1 - 0.0084 15.6 0.4 0.028 14.0 0.9 1.7 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like FAM222A PF15258.6 ORY45269.1 - 0.032 13.4 0.1 0.037 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein family of FAM222A Cu2_monooxygen PF01082.20 ORY45269.1 - 0.14 12.4 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Copper type II ascorbate-dependent monooxygenase, N-terminal domain zf-C2H2_jaz PF12171.8 ORY45269.1 - 6.2 7.2 6.1 20 5.6 5.2 2.3 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF4131 PF13567.6 ORY45270.1 - 1.7 8.3 5.7 1.2 8.8 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Pkinase PF00069.25 ORY45271.1 - 7.6e-19 68.1 0.0 6.8e-18 65.0 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY45271.1 - 2e-08 33.8 0.0 1.7e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Cbl_N PF02262.16 ORY45271.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 RuvX PF03652.15 ORY45271.1 - 0.13 12.7 0.1 0.29 11.5 0.1 1.5 1 0 0 1 1 1 0 Holliday junction resolvase DUF89 PF01937.19 ORY45272.1 - 1.5e-94 316.9 0.0 1.7e-94 316.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Sec3_C PF09763.9 ORY45273.1 - 7.9e-116 388.1 18.9 1.2e-115 387.5 18.9 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 ORY45273.1 - 0.0002 21.4 0.9 0.29 11.3 0.6 3.1 1 1 1 2 2 2 2 Exocyst complex component SEC3 N-terminal PIP2 binding PH GRAM PF02893.20 ORY45274.1 - 1.5e-31 108.7 4.2 1.1e-17 63.9 0.3 2.7 2 0 0 2 2 2 2 GRAM domain RabGAP-TBC PF00566.18 ORY45274.1 - 1.1e-28 100.4 0.5 7.4e-28 97.7 0.1 2.5 3 0 0 3 3 3 1 Rab-GTPase-TBC domain 2_5_RNA_ligase2 PF13563.6 ORY45274.1 - 6.8e-16 58.5 0.3 2.4e-15 56.8 0.3 1.9 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily MJ1316 PF04457.12 ORY45274.1 - 7.4e-16 58.7 0.1 2.4e-15 57.0 0.1 1.9 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain PAP_central PF04928.17 ORY45274.1 - 1.7e-08 33.8 0.2 2.3e-06 26.8 0.0 3.1 3 0 0 3 3 3 1 Poly(A) polymerase central domain Exo_endo_phos PF03372.23 ORY45274.1 - 9.2e-07 28.6 0.4 2.5e-06 27.2 0.4 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LigT_PEase PF02834.16 ORY45274.1 - 1.5e-05 25.1 0.1 0.0061 16.7 0.0 2.6 2 0 0 2 2 2 1 LigT like Phosphoesterase Nrap_D2 PF17403.2 ORY45274.1 - 2.8e-05 23.9 0.0 7.3e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain EF-hand_6 PF13405.6 ORY45274.1 - 0.0001 22.0 3.8 0.034 14.1 0.5 3.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 ORY45274.1 - 0.00032 20.0 6.4 0.05 13.2 1.4 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 ORY45274.1 - 0.0017 18.8 1.3 0.36 11.3 0.3 2.9 2 0 0 2 2 2 1 EF-hand domain pair NTP_transf_2 PF01909.23 ORY45274.1 - 0.0076 16.5 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4269 PF14091.6 ORY45274.1 - 0.09 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) EF-hand_5 PF13202.6 ORY45274.1 - 0.3 10.7 2.7 1.8 8.2 1.3 2.5 2 0 0 2 2 2 0 EF hand Abhydrolase_1 PF00561.20 ORY45275.1 - 4.9e-09 36.2 0.3 6.8e-09 35.8 0.3 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY45275.1 - 5.8e-09 35.6 0.2 7.6e-09 35.2 0.2 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY45275.1 - 5.4e-08 33.7 0.3 6.2e-08 33.5 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 ORY45275.1 - 0.0021 18.2 0.8 0.0032 17.6 0.8 1.2 1 0 0 1 1 1 1 Thioesterase domain UPF0227 PF05728.12 ORY45275.1 - 0.075 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.7 ORY45275.1 - 0.11 12.2 0.2 0.63 9.8 0.2 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 ORY45275.1 - 0.45 10.2 1.4 1 9.0 1.4 1.7 1 1 0 1 1 1 0 PGAP1-like protein Yip1 PF04893.17 ORY45276.1 - 1.2e-06 28.3 17.8 1.8e-06 27.8 17.8 1.3 1 0 0 1 1 1 1 Yip1 domain TMEM252 PF15664.5 ORY45276.1 - 0.18 11.5 3.1 0.26 11.0 1.0 2.1 1 1 1 2 2 2 0 Transmembrane protein 252 family DUF2070 PF09843.9 ORY45276.1 - 2.6 6.2 12.5 3 6.0 12.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) CLAMP PF14769.6 ORY45277.1 - 2.1e-17 63.4 0.0 3.4e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Flagellar C1a complex subunit C1a-32 CC2D2AN-C2 PF15625.6 ORY45278.1 - 1.7e-11 44.1 0.2 3.1e-10 40.1 0.2 2.6 1 1 0 1 1 1 1 CC2D2A N-terminal C2 domain DUF5523 PF17661.1 ORY45278.1 - 3e-10 40.2 12.2 3e-10 40.2 12.2 3.3 2 1 1 3 3 3 1 Family of unknown function (DUF5523) Squash PF00299.18 ORY45280.1 - 0.05 13.6 2.3 0.087 12.9 2.3 1.4 1 0 0 1 1 1 0 Squash family serine protease inhibitor Orthoreo_P10 PF07204.11 ORY45280.1 - 0.16 11.9 0.3 0.28 11.2 0.3 1.3 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DNase_II PF03265.15 ORY45284.1 - 0.031 13.6 0.1 0.033 13.5 0.1 1.1 1 0 0 1 1 1 0 Deoxyribonuclease II Drf_FH1 PF06346.12 ORY45285.1 - 0.01 15.6 7.8 0.018 14.8 7.8 1.3 1 0 0 1 1 1 0 Formin Homology Region 1 DUF3430 PF11912.8 ORY45287.1 - 0.035 14.2 0.4 0.044 13.8 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3430) Phage_Coat_B PF05356.11 ORY45287.1 - 0.25 11.3 4.1 0.48 10.4 3.3 1.8 2 0 0 2 2 2 0 Phage Coat protein B GTP_EFTU PF00009.27 ORY45288.1 - 2.3e-45 154.6 0.0 3.2e-45 154.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 ORY45288.1 - 3e-21 75.2 0.0 6.2e-21 74.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus LepA_C PF06421.12 ORY45288.1 - 7.2e-17 61.5 0.6 4e-07 30.2 0.0 2.5 1 1 1 2 2 2 2 GTP-binding protein LepA C-terminus GTP_EFTU_D2 PF03144.25 ORY45288.1 - 1.6e-07 31.6 0.0 2.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY45288.1 - 1.3e-05 25.2 0.0 3.1e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 ORY45288.1 - 0.0029 17.1 0.1 0.0086 15.5 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit RF3_C PF16658.5 ORY45288.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Roc PF08477.13 ORY45288.1 - 0.082 13.1 0.0 0.79 10.0 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TMEM107 PF14995.6 ORY45289.1 - 3.8e-13 50.0 4.9 1.5e-11 44.8 4.9 2.0 1 1 0 2 2 2 2 Transmembrane protein CHASE4 PF05228.13 ORY45293.1 - 0.11 12.7 1.0 0.2 11.9 1.0 1.6 1 1 0 1 1 1 0 CHASE4 domain DUF4929 PF16283.5 ORY45297.1 - 0.011 14.7 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4929) FPV060 PF17614.2 ORY45297.1 - 0.026 13.9 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Viral CC-type chemokine DUF499 PF04465.12 ORY45297.1 - 0.1 10.3 0.0 0.13 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF499) Bot1p PF12298.8 ORY45298.1 - 1.7e-21 77.1 2.7 4.4e-20 72.5 2.7 2.3 1 1 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.7 ORY45298.1 - 3.7e-05 24.0 0.0 5.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 SHIPPO-rpt PF07004.12 ORY45299.1 - 1.8e-16 60.2 61.4 0.0025 18.7 0.4 11.1 11 0 0 11 11 11 9 Sperm-tail PG-rich repeat Mago_nashi PF02792.14 ORY45300.1 - 1.8e-77 258.3 0.3 2e-77 258.1 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF3506 PF12014.8 ORY45300.1 - 0.13 12.3 0.0 0.17 11.9 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3506) Peptidase_C14 PF00656.22 ORY45301.1 - 4.6e-53 180.7 0.0 5.9e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.18 ORY45301.1 - 0.0087 15.6 0.1 0.018 14.5 0.1 1.6 1 1 0 1 1 1 1 Peptidase C13 family LRR_4 PF12799.7 ORY45302.1 - 3.9e-15 55.7 6.6 5.8e-06 26.5 4.0 4.5 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY45302.1 - 6e-14 51.6 33.9 6.5e-07 29.0 7.2 3.7 1 1 4 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 ORY45302.1 - 6.2e-08 32.1 18.5 0.086 13.4 0.5 7.7 6 2 1 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 ORY45302.1 - 1.6 9.0 11.8 1.7 8.9 1.3 4.4 4 0 0 4 4 4 0 Leucine Rich repeat LRR_4 PF12799.7 ORY45303.1 - 3.9e-15 55.7 6.6 5.8e-06 26.5 4.0 4.5 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY45303.1 - 6e-14 51.6 33.9 6.5e-07 29.0 7.2 3.7 1 1 4 5 5 5 4 Leucine rich repeat LRR_1 PF00560.33 ORY45303.1 - 6.2e-08 32.1 18.5 0.086 13.4 0.5 7.7 6 2 1 7 7 7 3 Leucine Rich Repeat LRR_6 PF13516.6 ORY45303.1 - 1.6 8.9 11.8 1.7 8.9 1.3 4.4 4 0 0 4 4 4 0 Leucine Rich repeat Ribosomal_S30 PF04758.14 ORY45304.1 - 9e-18 64.2 2.2 9.2e-18 64.2 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S30 LRR_8 PF13855.6 ORY45305.1 - 3.4e-14 52.3 18.5 1e-07 31.6 7.5 4.5 1 1 4 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 ORY45305.1 - 1e-09 38.5 20.3 0.00029 21.2 0.1 5.3 5 2 0 5 5 5 3 Leucine Rich repeats (2 copies) F-box PF00646.33 ORY45305.1 - 0.0015 18.4 0.5 0.0042 16.9 0.2 2.0 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 ORY45305.1 - 0.0016 18.7 25.8 0.16 12.6 0.2 7.8 8 0 0 8 8 8 2 Leucine Rich Repeat F-box-like PF12937.7 ORY45305.1 - 0.0058 16.5 0.1 0.014 15.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like DUF3338 PF11819.8 ORY45305.1 - 0.12 12.3 2.0 0.56 10.2 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3338) LRR_6 PF13516.6 ORY45305.1 - 1.6 8.9 13.1 46 4.4 0.6 5.7 5 0 0 5 5 5 0 Leucine Rich repeat Paf1 PF03985.13 ORY45306.1 - 6.3e-42 144.1 21.1 5.3e-41 141.0 21.1 2.1 1 1 0 1 1 1 1 Paf1 PilO PF04350.13 ORY45306.1 - 0.11 12.7 6.1 0.24 11.6 6.1 1.5 1 0 0 1 1 1 0 Pilus assembly protein, PilO Methyltransf_28 PF02636.17 ORY45307.1 - 6.8e-42 143.9 0.0 9.2e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.20 ORY45307.1 - 0.026 13.6 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 ORY45307.1 - 0.061 14.1 0.0 0.13 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain AA_permease_2 PF13520.6 ORY45308.1 - 2e-45 155.4 48.9 2e-45 155.4 48.9 1.7 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 ORY45308.1 - 1.2e-17 63.7 52.9 8.7e-17 60.9 52.9 1.9 1 1 0 1 1 1 1 Amino acid permease RE_HaeII PF09554.10 ORY45308.1 - 0.11 11.7 0.2 2.2 7.4 0.0 2.0 2 0 0 2 2 2 0 HaeII restriction endonuclease DUF3930 PF13067.6 ORY45308.1 - 0.33 11.2 0.1 0.33 11.2 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3930) LRR_8 PF13855.6 ORY45309.1 - 2e-15 56.3 36.8 1.2e-07 31.4 4.9 4.4 3 1 4 7 7 7 4 Leucine rich repeat LRR_4 PF12799.7 ORY45309.1 - 9.6e-09 35.4 15.5 0.00014 22.2 2.2 3.9 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) F-box PF00646.33 ORY45309.1 - 0.00033 20.4 0.0 0.00069 19.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY45309.1 - 0.00079 19.3 0.0 0.002 18.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 ORY45309.1 - 0.0015 18.8 16.2 0.38 11.5 0.6 5.9 6 0 0 6 6 6 1 Leucine Rich Repeat Sigma70_ner PF04546.13 ORY45309.1 - 0.086 12.7 0.1 0.14 12.1 0.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Terminase_3C PF17288.2 ORY45309.1 - 0.093 13.1 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Terminase RNAseH like domain Fib_alpha PF08702.10 ORY45309.1 - 0.13 12.4 0.8 0.24 11.6 0.8 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family IFT57 PF10498.9 ORY45309.1 - 0.14 11.1 1.0 0.21 10.5 1.0 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 WD40 PF00400.32 ORY45310.1 - 1.1e-46 155.8 9.2 5.3e-09 36.6 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 ORY45310.1 - 3.2e-42 143.8 1.0 6.3e-42 142.9 1.0 1.5 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 ORY45310.1 - 1.8e-13 50.6 0.2 0.0022 18.3 0.0 4.5 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 ORY45310.1 - 1.1e-06 28.4 0.1 6.6e-06 25.9 0.0 2.4 2 0 0 2 2 2 1 LisH Ge1_WD40 PF16529.5 ORY45310.1 - 1.7e-05 24.0 0.8 0.097 11.6 0.0 3.7 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ORY45310.1 - 0.0093 15.3 0.0 9.3 5.5 0.0 3.5 2 1 4 6 6 6 2 WD40-like domain Nup160 PF11715.8 ORY45310.1 - 0.014 14.1 0.3 8 5.0 0.1 3.3 2 2 2 4 4 4 0 Nucleoporin Nup120/160 ELYS-bb PF16687.5 ORY45310.1 - 0.11 11.1 0.0 4.2 5.9 0.0 2.4 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin DUF2385 PF09539.10 ORY45311.1 - 0.68 10.5 4.6 22 5.6 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2385) LRR_8 PF13855.6 ORY45313.1 - 2.3e-16 59.3 13.6 8.7e-06 25.4 1.0 3.7 1 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY45313.1 - 2.5e-15 56.3 10.4 1.9e-05 24.9 0.1 4.0 3 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY45313.1 - 1.3e-06 28.1 9.3 2.6 8.9 0.1 7.0 6 0 0 6 6 6 2 Leucine Rich Repeat F-box PF00646.33 ORY45313.1 - 1.8e-06 27.6 0.1 3.9e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.6 ORY45313.1 - 0.0043 17.0 5.2 2.7 8.3 0.0 4.6 4 0 0 4 4 4 2 Leucine Rich repeat F-box-like PF12937.7 ORY45313.1 - 0.0061 16.4 0.2 0.017 15.0 0.2 1.8 1 0 0 1 1 1 1 F-box-like GREB1 PF15782.5 ORY45315.1 - 8.6 3.3 18.2 11 3.0 18.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LRR_8 PF13855.6 ORY45317.1 - 9.3e-21 73.4 32.3 1.6e-10 40.6 5.5 4.8 3 2 3 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 ORY45317.1 - 6.5e-12 45.5 16.0 4.8e-05 23.6 0.4 4.8 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY45317.1 - 4.2e-06 26.6 15.3 0.75 10.6 0.0 7.2 8 0 0 8 8 8 2 Leucine Rich Repeat DUF3338 PF11819.8 ORY45317.1 - 0.083 12.9 0.0 13 5.7 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3338) LRR_6 PF13516.6 ORY45317.1 - 0.47 10.6 11.3 2.9 8.2 0.8 4.6 4 0 0 4 4 4 0 Leucine Rich repeat ABC1 PF03109.16 ORY45320.1 - 1.8e-30 105.6 0.2 3.3e-30 104.7 0.2 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 ORY45320.1 - 0.002 18.1 0.2 0.0084 16.0 0.2 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Med15_fungi PF05397.12 ORY45320.1 - 0.0022 18.2 0.2 0.0058 16.9 0.2 1.7 1 0 0 1 1 1 1 Mediator complex subunit 15 Pkinase PF00069.25 ORY45320.1 - 0.16 11.3 0.0 0.5 9.7 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain SAM_2 PF07647.17 ORY45321.1 - 3.5e-05 23.8 0.0 0.00016 21.7 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 ORY45321.1 - 8.6e-05 22.4 0.0 0.00023 21.1 0.0 1.7 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_1 PF00536.30 ORY45321.1 - 0.00011 22.5 0.0 0.00026 21.4 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_Ste50p PF09235.10 ORY45321.1 - 0.057 13.7 0.0 0.18 12.1 0.0 1.9 1 0 0 1 1 1 0 Ste50p, sterile alpha motif PTP_tm PF18861.1 ORY45321.1 - 0.51 10.3 2.8 0.75 9.8 0.7 2.1 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J ANF_receptor PF01094.28 ORY45322.1 - 4.5e-20 72.0 0.0 5.6e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 ORY45323.1 - 1e-16 61.4 14.9 1.7e-16 60.7 14.9 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR 7tm_3 PF00003.22 ORY45324.1 - 1.8e-22 80.2 17.1 2.8e-22 79.6 17.1 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 ORY45324.1 - 2.6e-08 33.4 0.1 4e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region AIM3 PF17096.5 ORY45324.1 - 0.24 12.4 7.7 0.86 10.6 7.7 1.9 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 3 zf-NOSIP PF15906.5 ORY45325.1 - 4.8e-11 42.6 0.2 9.4e-11 41.7 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_3 PF13920.6 ORY45325.1 - 3.4e-07 30.0 18.4 0.00019 21.2 8.7 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY45325.1 - 3.1e-06 26.9 19.3 0.00046 20.0 7.6 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY45325.1 - 3.3e-05 23.8 14.7 0.0042 17.1 5.3 2.5 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_2 PF13639.6 ORY45325.1 - 6.4e-05 23.2 16.5 0.00018 21.8 6.4 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.6 ORY45325.1 - 0.0003 20.6 18.7 0.0029 17.4 7.3 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY45325.1 - 0.00032 20.6 7.0 0.00032 20.6 7.0 2.4 2 0 0 2 2 2 1 zinc-RING finger domain Rtf2 PF04641.12 ORY45325.1 - 0.0016 17.8 1.1 0.0016 17.8 1.1 2.0 2 0 0 2 2 2 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 ORY45325.1 - 0.013 15.3 18.6 0.36 10.7 8.7 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 ORY45325.1 - 0.096 12.9 16.4 1.3 9.2 2.2 2.9 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 ORY45325.1 - 1.6 8.9 14.9 5.2 7.3 7.5 2.5 2 1 0 2 2 2 0 zinc RING finger of MSL2 FYVE PF01363.21 ORY45325.1 - 7 6.9 16.9 0.3 11.3 7.9 2.6 2 2 0 2 2 2 0 FYVE zinc finger zf-RING_4 PF14570.6 ORY45325.1 - 9 6.2 18.8 1.6 8.6 9.1 3.2 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain 7tm_3 PF00003.22 ORY45326.1 - 2.1e-21 76.8 23.4 4.2e-21 75.8 23.4 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 ORY45326.1 - 1.1e-20 74.1 0.0 1.6e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY45326.1 - 4.1e-05 23.4 0.2 8.3e-05 22.4 0.2 1.4 1 0 0 1 1 1 1 Periplasmic binding protein Ost5 PF05251.12 ORY45326.1 - 2.4 8.5 9.3 0.09 13.1 1.6 2.7 3 0 0 3 3 3 0 Oligosaccharyltransferase subunit 5 ADP_ribosyl_GH PF03747.14 ORY45327.1 - 1.9e-14 54.1 0.0 2.3e-14 53.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase ADP_ribosyl_GH PF03747.14 ORY45328.1 - 2.4e-15 57.0 0.0 2.8e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase 7tm_3 PF00003.22 ORY45329.1 - 4.5e-24 85.5 17.7 6.3e-24 85.0 17.7 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR RRM_1 PF00076.22 ORY45331.1 - 4.9e-13 48.7 0.1 7.6e-13 48.1 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 ORY45331.1 - 1e-07 31.7 3.5 1.6e-07 31.1 3.5 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 ORY45331.1 - 0.00038 20.1 2.8 0.0013 18.4 1.3 2.2 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 ORY45331.1 - 0.011 15.6 0.6 0.017 15.0 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 ORY45331.1 - 0.023 14.7 0.2 0.039 13.9 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Rep_fac_C PF08542.11 ORY45332.1 - 1.1e-12 48.2 0.1 2.8e-12 46.9 0.1 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 ORY45332.1 - 9.7e-08 32.5 0.1 3.1e-07 30.9 0.1 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 ORY45332.1 - 1.5e-06 28.1 0.1 6.1e-06 26.1 0.0 1.9 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_assoc_2 PF16193.5 ORY45332.1 - 0.00091 19.5 0.1 0.0095 16.3 0.0 2.3 2 0 0 2 2 2 1 AAA C-terminal domain Arm PF00514.23 ORY45333.1 - 6.2e-26 89.6 14.6 6.8e-09 35.5 0.0 7.4 8 0 0 8 8 8 4 Armadillo/beta-catenin-like repeat HEAT PF02985.22 ORY45333.1 - 2e-14 52.5 5.2 0.071 13.4 0.0 6.6 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.6 ORY45333.1 - 2.9e-14 53.2 3.0 0.0037 17.6 0.3 4.5 1 1 4 5 5 5 4 HEAT repeats HEAT_EZ PF13513.6 ORY45333.1 - 7.7e-11 42.3 13.0 0.001 19.5 0.2 6.1 5 1 1 6 6 6 3 HEAT-like repeat Cnd1 PF12717.7 ORY45333.1 - 3.9e-07 30.3 0.0 0.019 15.0 0.0 3.0 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DNA_alkylation PF08713.11 ORY45333.1 - 1e-05 25.4 0.0 1.6 8.4 0.0 4.2 2 1 3 5 5 5 2 DNA alkylation repair enzyme Adaptin_N PF01602.20 ORY45333.1 - 2.9e-05 22.8 0.0 0.013 14.1 0.0 3.0 2 1 0 2 2 2 2 Adaptin N terminal region CHASE6_C PF17150.4 ORY45333.1 - 8.4e-05 23.2 0.2 14 6.4 0.0 5.6 5 1 1 6 6 6 0 C-terminal domain of two-partite extracellular sensor domain RICTOR_V PF14668.6 ORY45333.1 - 0.0018 18.4 0.0 1.6 9.0 0.0 2.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 ORY45333.1 - 0.0045 17.5 7.4 0.92 10.4 0.0 4.9 5 0 0 5 5 4 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.9 ORY45333.1 - 0.061 11.8 0.0 0.4 9.1 0.0 1.8 1 1 0 1 1 1 0 Proteasome non-ATPase 26S subunit HEAT_UF PF18817.1 ORY45333.1 - 0.072 13.4 0.3 1.8 8.9 0.0 3.3 4 0 0 4 4 4 0 Repeat of uncharacterized protein PH0542 Vac14_Fab1_bd PF12755.7 ORY45333.1 - 0.12 13.0 0.0 2.1 9.0 0.0 2.8 1 1 1 2 2 2 0 Vacuolar 14 Fab1-binding region Arm_2 PF04826.13 ORY45333.1 - 0.12 11.8 0.1 45 3.4 0.0 3.5 2 1 3 5 5 5 0 Armadillo-like TPR_12 PF13424.6 ORY45333.1 - 0.13 12.5 1.7 0.9 9.9 0.2 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat API5 PF05918.11 ORY45333.1 - 0.18 10.6 0.0 22 3.7 0.0 2.8 1 1 2 3 3 3 0 Apoptosis inhibitory protein 5 (API5) TPR_16 PF13432.6 ORY45333.1 - 0.22 12.2 2.4 5.2 7.8 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TMEM220 PF15071.6 ORY45334.1 - 5.4 7.8 6.7 2.2 9.1 0.3 2.7 2 1 0 2 2 2 0 Transmembrane family 220, helix KDZ PF18758.1 ORY45336.1 - 3.8e-19 69.2 0.0 9e-19 68.0 0.0 1.7 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase Death PF00531.22 ORY45339.1 - 0.019 15.1 0.2 4 7.7 0.1 2.7 2 0 0 2 2 2 0 Death domain dUTPase PF00692.19 ORY45340.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 dUTPase CoatB PF10389.9 ORY45341.1 - 0.85 9.5 6.8 2.5 8.0 6.8 1.9 1 0 0 1 1 1 0 Bacteriophage coat protein B LRR_4 PF12799.7 ORY45342.1 - 6e-15 55.1 12.7 8.6e-05 22.8 0.5 4.7 1 1 6 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY45342.1 - 1.9e-14 53.2 12.4 0.00012 21.7 0.7 4.1 1 1 3 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 ORY45342.1 - 1.7e-06 27.8 18.7 3.7 8.5 0.2 7.4 6 1 0 6 6 6 4 Leucine Rich Repeat F-box PF00646.33 ORY45342.1 - 1.2e-05 25.0 0.0 2.7e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY45342.1 - 0.00086 19.1 0.0 0.0027 17.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like Sde2_N_Ubi PF13019.6 ORY45342.1 - 0.19 11.6 1.2 0.31 10.9 1.2 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain CPSF_A PF03178.15 ORY45343.1 - 4e-32 111.8 0.0 1e-31 110.5 0.0 1.7 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 ORY45343.1 - 1.7e-24 86.3 0.0 3.8e-22 78.6 0.0 3.4 2 1 1 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term PQQ_3 PF13570.6 ORY45343.1 - 1.8 9.1 5.7 14 6.3 0.0 4.3 4 0 0 4 4 4 0 PQQ-like domain MFS_1 PF07690.16 ORY45344.1 - 2.1e-11 43.4 25.2 7.2e-10 38.3 19.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 ORY45345.1 - 2.2e-09 36.7 32.8 2.3e-09 36.6 20.8 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily SpoIIE PF07228.12 ORY45346.1 - 3.9e-09 36.7 0.0 4.7e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 ORY45346.1 - 9.5e-09 35.2 0.1 1.1e-08 35.0 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 ORY45346.1 - 4.4e-08 33.1 0.0 0.0015 18.2 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C LRR_8 PF13855.6 ORY45349.1 - 1.5e-14 53.5 17.9 5.8e-09 35.6 7.3 2.4 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY45349.1 - 2.8e-13 49.8 29.8 2.8e-05 24.4 1.7 3.3 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY45349.1 - 1.5e-06 27.9 11.2 4.2 8.3 0.1 5.4 5 0 0 5 5 5 4 Leucine Rich Repeat LRR_9 PF14580.6 ORY45349.1 - 0.0034 16.9 0.3 0.0049 16.4 0.3 1.3 1 0 0 1 1 1 1 Leucine-rich repeat Ank_2 PF12796.7 ORY45350.1 - 1.8e-15 57.3 0.1 2.6e-07 31.1 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY45350.1 - 3.4e-12 46.3 0.2 0.28 11.6 0.0 5.8 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY45350.1 - 4.7e-09 36.6 0.2 0.00066 20.2 0.0 3.6 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY45350.1 - 3.5e-06 26.9 2.3 2.8 8.8 0.0 6.6 7 1 1 8 8 8 1 Ankyrin repeat F-box PF00646.33 ORY45350.1 - 1.5e-05 24.7 0.7 3.6e-05 23.5 0.7 1.7 1 0 0 1 1 1 1 F-box domain Ank PF00023.30 ORY45350.1 - 1.9e-05 24.9 2.4 6.7 7.3 0.0 5.6 5 1 0 5 5 5 2 Ankyrin repeat F-box-like PF12937.7 ORY45350.1 - 0.0028 17.5 0.3 0.0077 16.1 0.3 1.8 1 0 0 1 1 1 1 F-box-like RNB PF00773.19 ORY45350.1 - 0.21 10.9 0.7 0.38 10.0 0.2 1.6 2 0 0 2 2 2 0 RNB domain DUF4446 PF14584.6 ORY45352.1 - 0.078 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) EphA2_TM PF14575.6 ORY45352.1 - 0.15 13.0 0.0 0.29 12.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Acetyltransf_7 PF13508.7 ORY45354.1 - 1e-09 38.6 0.1 0.0022 18.4 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY45354.1 - 2.4e-07 30.7 0.0 0.012 15.6 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY45354.1 - 5.8e-07 29.8 0.3 0.036 14.3 0.1 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 ORY45354.1 - 9.4e-07 29.0 0.1 0.11 12.6 0.0 4.0 4 0 0 4 4 4 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY45354.1 - 0.00041 20.3 0.1 0.41 10.6 0.0 2.4 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_7 PF13508.7 ORY45356.1 - 0.00027 21.3 0.0 0.00039 20.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY45356.1 - 0.0003 20.9 0.0 0.013 15.5 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY45356.1 - 0.002 18.1 0.0 0.003 17.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY45356.1 - 0.0095 16.2 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Calreticulin PF00262.18 ORY45358.1 - 3e-78 263.3 19.2 1.1e-60 205.5 7.0 2.5 2 1 1 3 3 3 2 Calreticulin family CSN5_C PF18323.1 ORY45358.1 - 3.4 8.6 10.4 6.5 7.7 10.4 1.4 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain CDC45 PF02724.14 ORY45358.1 - 8 4.6 12.4 12 4.0 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein LRR_8 PF13855.6 ORY45359.1 - 6.3e-24 83.5 36.6 6.9e-08 32.1 5.2 5.8 1 1 5 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 ORY45359.1 - 2e-18 66.2 42.6 2.1e-07 31.1 3.0 6.2 2 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY45359.1 - 6.9e-08 32.0 36.3 0.18 12.4 0.1 9.1 9 2 0 9 9 9 4 Leucine Rich Repeat LRR_9 PF14580.6 ORY45359.1 - 4.4e-06 26.3 7.6 0.00023 20.7 1.5 2.6 2 1 1 3 3 3 2 Leucine-rich repeat F-box-like PF12937.7 ORY45359.1 - 0.00018 21.4 0.0 0.00052 19.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 ORY45359.1 - 0.00062 19.6 33.7 0.58 10.4 0.1 7.9 8 0 0 8 8 8 4 Leucine Rich repeat F-box PF00646.33 ORY45359.1 - 0.002 18.0 0.0 0.006 16.4 0.0 1.9 1 0 0 1 1 1 1 F-box domain LRR_5 PF13306.6 ORY45359.1 - 0.025 14.5 2.1 0.063 13.2 0.5 2.0 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) LRR_2 PF07723.13 ORY45359.1 - 0.26 12.0 1.6 38 5.2 0.0 3.5 2 1 0 2 2 2 0 Leucine Rich Repeat cNMP_binding PF00027.29 ORY45361.1 - 9.9e-20 70.4 0.1 3.9e-19 68.5 0.0 2.1 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 ORY45361.1 - 4.6e-07 29.3 11.4 8.4e-07 28.5 11.4 1.3 1 0 0 1 1 1 1 Ion transport protein Co_AT_N PF12557.8 ORY45361.1 - 0.45 10.5 2.8 1.1 9.3 2.8 1.5 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal cNMP_binding PF00027.29 ORY45362.1 - 8.4e-20 70.6 0.0 3e-19 68.9 0.1 1.9 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain GST_N_3 PF13417.6 ORY45363.1 - 3.9e-12 46.4 0.1 6.7e-12 45.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY45363.1 - 2.1e-08 34.3 0.0 3.4e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY45363.1 - 7.4e-07 29.4 0.0 1.5e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_5 PF18485.1 ORY45363.1 - 0.0097 16.3 0.0 0.021 15.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY45363.1 - 0.12 12.4 0.3 0.21 11.6 0.3 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain LRR_8 PF13855.6 ORY45364.1 - 6.1e-17 61.1 35.6 2.2e-06 27.3 3.2 4.4 1 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY45364.1 - 3.8e-15 55.7 35.3 2e-05 24.8 3.2 5.8 2 2 5 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY45364.1 - 7.2e-11 41.1 37.2 0.00027 21.1 1.2 8.5 9 0 0 9 9 9 5 Leucine Rich Repeat LRR_6 PF13516.6 ORY45364.1 - 0.048 13.7 29.5 1.2 9.3 0.4 6.2 8 0 0 8 8 8 0 Leucine Rich repeat TetR_C_37 PF18665.1 ORY45366.1 - 0.042 14.5 0.5 0.086 13.5 0.5 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain CNH PF00780.22 ORY45367.1 - 1.3e-52 179.1 0.1 4.6e-52 177.3 0.0 1.8 2 0 0 2 2 2 1 CNH domain RhoGEF PF00621.20 ORY45367.1 - 1.1e-35 123.6 2.1 1.9e-35 122.8 2.1 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 ORY45367.1 - 5.4e-08 32.8 0.0 1.4e-07 31.5 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_5 PF15405.6 ORY45367.1 - 5.9e-07 29.6 0.0 2.2e-05 24.6 0.0 2.6 1 1 1 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 ORY45367.1 - 0.0036 17.1 0.0 0.094 12.5 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain PH_16 PF17838.1 ORY45367.1 - 0.0098 15.7 0.3 0.13 12.1 0.0 2.8 3 0 0 3 3 3 1 PH domain UvrD-helicase PF00580.21 ORY45367.1 - 0.042 13.4 0.1 0.082 12.4 0.1 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Myb_DNA-bind_7 PF15963.5 ORY45368.1 - 6.3e-21 74.1 0.1 7.8e-21 73.8 0.1 1.1 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 ORY45368.1 - 4.7e-05 23.5 0.0 7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY45368.1 - 0.021 15.1 0.1 0.028 14.7 0.1 1.2 1 0 0 1 1 1 0 Myb-like DNA-binding domain Ribosomal_S19 PF00203.21 ORY45369.1 - 1.4e-22 79.3 0.0 2.5e-22 78.6 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S19 Zn_clus PF00172.18 ORY45371.1 - 4.4e-05 23.5 5.6 9e-05 22.5 5.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NTP_transf_7 PF07984.12 ORY45371.1 - 0.2 10.8 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyltransferase SPATA1_C PF15743.5 ORY45454.1 - 0.0034 17.5 3.6 0.0053 16.8 3.6 1.2 1 0 0 1 1 1 1 Spermatogenesis-associated C-terminus DUF3015 PF11220.8 ORY45454.1 - 0.014 15.2 1.2 0.034 14.0 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) DUF4355 PF14265.6 ORY45454.1 - 0.099 12.9 7.7 0.19 12.0 7.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) FlaC_arch PF05377.11 ORY45454.1 - 0.44 11.0 2.2 2.7 8.4 0.1 2.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) GET2 PF08690.10 ORY45454.1 - 1.2 8.7 7.6 2.7 7.6 2.6 2.3 2 0 0 2 2 2 0 GET complex subunit GET2 TMPIT PF07851.13 ORY45454.1 - 3.8 6.7 6.1 5.8 6.1 6.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF2203 PF09969.9 ORY45454.1 - 5.4 7.7 6.9 8.6 7.1 5.8 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Luciferase_3H PF10284.9 ORY45455.1 - 0.37 11.0 11.6 4.7 7.4 1.0 3.2 2 1 1 3 3 3 0 Luciferase helical bundle domain U3_snoRNA_assoc PF08297.11 ORY45455.1 - 7.4 7.4 6.1 5.8 7.7 0.6 2.6 1 1 1 2 2 2 0 U3 snoRNA associated OPT PF03169.15 ORY45456.1 - 7.9e-124 414.6 57.3 1e-123 414.2 57.3 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FAD_binding_3 PF01494.19 ORY45457.1 - 3.7e-24 85.6 0.1 2.6e-23 82.8 0.1 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY45457.1 - 1.8e-05 24.5 0.4 0.0084 15.7 0.5 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.10 ORY45457.1 - 0.00015 20.9 0.0 0.00033 19.8 0.0 1.5 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 ORY45457.1 - 0.0054 16.9 1.3 0.011 15.9 0.2 2.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY45457.1 - 0.03 13.5 0.2 1.9 7.6 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY45457.1 - 0.035 13.4 0.1 5.4 6.2 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY45457.1 - 0.08 13.5 0.1 2.1 8.9 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase OPT PF03169.15 ORY45459.1 - 2.7e-94 317.0 41.0 3.8e-94 316.5 41.0 1.2 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CMAS PF02353.20 ORY45462.1 - 4.1e-64 216.5 0.8 5.1e-64 216.2 0.8 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 ORY45462.1 - 4.4e-11 43.3 0.1 7.7e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY45462.1 - 1.9e-10 41.3 0.0 3.9e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY45462.1 - 4.3e-10 39.7 0.0 7.2e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY45462.1 - 5.4e-07 29.3 0.0 8.7e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 ORY45462.1 - 7e-07 29.9 0.0 1.3e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY45462.1 - 6e-06 26.1 0.0 1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 ORY45462.1 - 0.0018 17.7 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 ORY45462.1 - 0.0032 16.6 0.0 0.0055 15.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.18 ORY45462.1 - 0.0048 16.3 0.1 0.008 15.5 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 ORY45462.1 - 0.028 13.9 0.0 0.07 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_18 PF12847.7 ORY45462.1 - 0.03 14.2 0.0 0.063 13.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 ORY45462.1 - 0.035 13.9 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein DOT1 PF08123.13 ORY45462.1 - 0.042 13.4 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 FtsJ PF01728.19 ORY45462.1 - 0.051 13.7 0.1 0.11 12.7 0.1 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 ORY45462.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) B PF02216.16 ORY45462.1 - 0.17 11.9 0.0 0.45 10.6 0.0 1.7 1 0 0 1 1 1 0 B domain LRR_1 PF00560.33 ORY45463.1 - 0.19 12.4 0.5 31 5.7 0.0 3.2 2 1 1 3 3 3 0 Leucine Rich Repeat CMAS PF02353.20 ORY45464.1 - 6.1e-67 225.8 0.4 7.7e-67 225.5 0.4 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 ORY45464.1 - 4.6e-12 46.1 0.0 9.3e-12 45.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY45464.1 - 5e-12 46.4 0.0 9.1e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY45464.1 - 7e-12 45.8 0.0 1.5e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY45464.1 - 2.7e-07 31.3 0.0 4.8e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY45464.1 - 1.1e-05 25.2 0.0 2.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY45464.1 - 5.5e-05 22.8 0.0 9.1e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 ORY45464.1 - 0.0013 18.5 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein RrnaAD PF00398.20 ORY45464.1 - 0.0015 17.7 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.18 ORY45464.1 - 0.0033 16.8 0.1 0.0061 15.9 0.1 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family UPF0020 PF01170.18 ORY45464.1 - 0.012 15.4 0.1 0.085 12.5 0.1 2.0 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 FtsJ PF01728.19 ORY45464.1 - 0.014 15.6 0.0 0.022 14.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DOT1 PF08123.13 ORY45464.1 - 0.017 14.6 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_15 PF09445.10 ORY45464.1 - 0.04 13.5 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 ORY45464.1 - 0.047 13.1 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 ORY45464.1 - 0.058 13.1 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 ORY45464.1 - 0.08 12.9 0.0 0.17 11.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 ORY45464.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain WD40 PF00400.32 ORY45465.1 - 8.9e-08 32.7 12.4 0.00053 20.7 0.1 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat F-box-like PF12937.7 ORY45465.1 - 2.7e-06 27.2 3.8 6.2e-06 26.0 3.8 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY45465.1 - 7.2e-06 25.8 2.6 1.4e-05 24.8 2.6 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 ORY45465.1 - 0.15 12.3 0.0 13 6.2 0.0 3.2 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain UIM PF02809.20 ORY45465.1 - 1.5 8.9 9.5 5.4 7.2 2.3 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif WD40 PF00400.32 ORY45466.1 - 7.2e-23 80.4 19.4 1.5e-06 28.8 0.3 6.4 6 1 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 ORY45466.1 - 8.2e-08 31.3 4.3 0.0022 16.7 0.1 3.8 2 1 2 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY45466.1 - 3.7e-07 29.8 0.6 6.8e-07 28.9 0.5 1.6 1 1 0 1 1 1 1 WD40-like domain BBS2_Mid PF14783.6 ORY45466.1 - 5.9e-06 26.3 0.1 0.015 15.3 0.0 3.6 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region ANAPC4_WD40 PF12894.7 ORY45466.1 - 0.00017 21.8 1.7 0.009 16.3 0.2 3.1 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PALB2_WD40 PF16756.5 ORY45466.1 - 0.0068 15.4 3.8 0.99 8.3 0.1 3.1 2 1 1 3 3 3 1 Partner and localizer of BRCA2 WD40 domain DUF4402 PF14352.6 ORY45466.1 - 0.018 15.7 0.5 3.3 8.4 0.2 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4402) DUF1487 PF07368.11 ORY45466.1 - 0.056 12.9 0.2 0.22 11.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) BRK PF07533.16 ORY45466.1 - 0.11 12.1 0.0 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 BRK domain Bet_v_1 PF00407.19 ORY45466.1 - 0.2 11.5 1.7 0.81 9.6 0.3 2.4 1 1 1 3 3 3 0 Pathogenesis-related protein Bet v I family FAD_binding_3 PF01494.19 ORY45467.1 - 1.9e-17 63.6 0.9 4.5e-15 55.7 0.9 3.3 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 ORY45467.1 - 0.0063 15.6 0.0 0.055 12.5 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 ORY45467.1 - 0.034 14.4 0.2 0.078 13.2 0.2 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 ORY45468.1 - 3.8e-23 82.3 0.2 2.1e-22 79.9 0.2 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY45468.1 - 4.4e-05 23.2 1.6 0.098 12.2 1.5 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY45468.1 - 0.00043 19.6 1.1 0.25 10.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY45468.1 - 0.0069 16.6 0.9 0.053 13.8 0.4 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY45468.1 - 0.015 15.8 0.3 1.1 9.9 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 ORY45468.1 - 0.037 13.1 0.0 0.14 11.1 0.0 1.9 1 1 0 1 1 1 0 Squalene epoxidase FAD_binding_2 PF00890.24 ORY45468.1 - 0.28 10.2 2.0 0.56 9.2 2.0 1.5 1 0 0 1 1 1 0 FAD binding domain EF-hand_1 PF00036.32 ORY45469.1 - 8.6e-19 65.6 4.2 4.4e-06 25.9 0.5 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 ORY45469.1 - 4.5e-17 60.4 3.4 2.7e-05 23.7 0.6 4.9 5 1 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 ORY45469.1 - 8.7e-16 58.1 4.0 7.8e-10 39.1 1.5 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 ORY45469.1 - 2.7e-12 45.6 5.5 0.00097 18.5 0.3 4.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 ORY45469.1 - 2.2e-11 43.4 4.5 2.5e-07 30.4 2.3 4.5 3 2 1 4 4 4 2 EF-hand domain pair EF-hand_4 PF12763.7 ORY45469.1 - 2e-05 24.5 2.6 0.063 13.2 0.3 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORY45469.1 - 0.00013 22.2 0.1 0.37 11.1 0.0 2.7 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 ORY45469.1 - 0.00015 22.0 0.2 0.0034 17.7 0.1 2.7 3 1 0 3 3 3 1 EF-hand domain POTRA_2 PF08479.11 ORY45469.1 - 0.022 14.6 0.0 0.065 13.1 0.0 1.7 2 0 0 2 2 2 0 POTRA domain, ShlB-type HTH_IclR PF09339.10 ORY45469.1 - 0.16 11.8 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain FAD_binding_3 PF01494.19 ORY45472.1 - 2.3e-14 53.4 0.2 1.9e-07 30.7 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ORY45472.1 - 0.0027 17.9 1.0 0.0069 16.6 0.3 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY45472.1 - 0.0054 16.4 2.0 0.0068 16.0 2.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY45472.1 - 0.0083 15.2 1.9 0.012 14.7 1.9 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 ORY45472.1 - 0.032 14.8 0.3 0.081 13.5 0.3 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 ORY45472.1 - 0.04 13.0 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Pyr_redox_2 PF07992.14 ORY45472.1 - 0.076 12.2 0.3 0.21 10.8 0.4 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GST_N_4 PF17172.4 ORY45473.1 - 5.7e-09 36.6 0.0 8.9e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_N_3 PF13417.6 ORY45473.1 - 0.00084 19.7 0.0 0.0018 18.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 ORY45474.1 - 1.4e-11 44.0 0.0 1.7e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY45474.1 - 0.01 16.0 0.0 0.012 15.8 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FAD_binding_3 PF01494.19 ORY45476.1 - 1.6e-18 67.1 0.2 1.3e-17 64.1 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY45476.1 - 0.00016 21.4 1.2 0.0021 17.7 0.3 2.4 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY45476.1 - 0.00032 20.0 0.1 0.067 12.4 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY45476.1 - 0.0014 18.8 0.0 0.0041 17.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY45476.1 - 0.0015 19.0 0.1 0.046 14.3 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 ORY45476.1 - 0.04 13.0 0.0 0.65 9.0 0.0 2.3 3 0 0 3 3 3 0 Squalene epoxidase GIDA PF01134.22 ORY45476.1 - 0.088 11.9 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 ORY45477.1 - 2.1e-21 76.5 0.9 4.1e-10 39.4 0.2 2.8 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ORY45477.1 - 0.00019 20.7 0.7 0.4 9.9 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY45477.1 - 0.00099 19.3 1.1 0.0024 18.0 0.6 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY45477.1 - 0.018 14.6 5.2 0.21 11.2 4.9 2.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORY45477.1 - 0.026 15.1 0.3 0.9 10.1 0.3 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase EspF PF04806.12 ORY45477.1 - 0.12 12.8 0.7 0.68 10.4 0.1 2.1 2 0 0 2 2 2 0 EspF protein repeat UDPG_MGDP_dh_N PF03721.14 ORY45477.1 - 0.17 11.5 0.2 0.29 10.7 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.24 ORY45477.1 - 2.3 7.2 4.2 4.2 6.3 3.5 1.7 1 1 1 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 ORY45478.1 - 8.9e-16 58.1 2.0 3.8e-09 36.3 0.6 3.4 1 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 ORY45478.1 - 0.0018 18.5 0.4 0.004 17.3 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY45478.1 - 0.0037 16.9 3.5 0.019 14.5 2.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY45478.1 - 0.014 14.7 1.2 1.1 8.4 0.8 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 ORY45478.1 - 0.015 14.4 0.1 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase FAD_binding_2 PF00890.24 ORY45478.1 - 0.16 11.1 4.6 0.089 11.9 2.7 1.5 2 0 0 2 2 2 0 FAD binding domain DUF3987 PF13148.6 ORY45479.1 - 5e-15 55.4 0.0 1.1e-06 27.9 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF3987) NDC10_II PF16787.5 ORY45483.1 - 0.015 14.3 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 ORY45483.1 - 0.042 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes Pepdidase_M14_N PF18027.1 ORY45483.1 - 0.097 13.0 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Cytosolic carboxypeptidase N-terminal domain HAUS-augmin3 PF14932.6 ORY45485.1 - 4e-06 26.6 5.9 4e-06 26.6 5.9 1.4 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 3 Spc24 PF08286.11 ORY45485.1 - 0.023 14.9 1.7 0.055 13.7 1.7 1.7 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF4349 PF14257.6 ORY45485.1 - 0.036 13.5 1.1 0.078 12.4 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) V_ATPase_I PF01496.19 ORY45485.1 - 0.04 11.9 2.0 0.053 11.4 2.0 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF5082 PF16888.5 ORY45485.1 - 0.064 13.5 3.4 0.26 11.6 3.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) BLOC1_2 PF10046.9 ORY45485.1 - 0.19 12.0 4.8 0.46 10.8 1.5 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cortex-I_coil PF09304.10 ORY45485.1 - 0.33 11.2 0.1 0.33 11.2 0.1 2.6 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF3450 PF11932.8 ORY45485.1 - 0.46 9.7 5.3 1.9 7.7 5.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) AKNA PF12443.8 ORY45485.1 - 0.63 10.7 3.6 0.7 10.6 0.1 2.6 2 1 1 3 3 3 0 AT-hook-containing transcription factor zf-C2H2 PF00096.26 ORY45487.1 - 0.0088 16.4 1.6 0.02 15.3 1.6 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ORY45487.1 - 0.057 13.4 0.4 0.098 12.7 0.4 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger EIN3 PF04873.13 ORY45487.1 - 0.1 11.9 0.4 0.19 11.0 0.4 1.3 1 0 0 1 1 1 0 Ethylene insensitive 3 EMP24_GP25L PF01105.24 ORY45488.1 - 0.018 15.0 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF1874 PF08960.10 ORY45489.1 - 0.15 12.2 0.4 15 5.8 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1874) YIF1 PF03878.15 ORY45490.1 - 0.18 11.3 4.4 0.19 11.2 4.4 1.1 1 0 0 1 1 1 0 YIF1 KAsynt_C_assoc PF16197.5 ORY45494.1 - 0.0094 16.4 0.0 0.012 16.0 0.0 1.2 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension DEAD PF00270.29 ORY45499.1 - 3.5e-39 134.4 0.1 8.6e-39 133.1 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY45499.1 - 2e-18 66.8 0.0 1.1e-17 64.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY45499.1 - 1.3e-06 28.5 0.0 4.5e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RhoGAP PF00620.27 ORY45499.1 - 1.6e-06 28.0 0.1 3.4e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain ERCC3_RAD25_C PF16203.5 ORY45499.1 - 0.0067 15.7 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CBM9_1 PF06452.11 ORY45500.1 - 2.5e-07 30.8 0.0 5.5e-07 29.7 0.0 1.6 2 0 0 2 2 2 1 Carbohydrate family 9 binding domain-like CBM9_2 PF16011.5 ORY45500.1 - 0.0023 17.7 1.1 0.0029 17.3 0.1 1.7 2 0 0 2 2 2 1 Carbohydrate-binding family 9 Pkinase PF00069.25 ORY45501.1 - 6e-37 127.4 0.7 4.4e-35 121.3 0.7 2.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY45501.1 - 1.1e-18 67.5 0.5 1.3e-17 64.0 0.5 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Coleoptericin PF06286.11 ORY45501.1 - 0.13 12.4 0.1 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Coleoptericin DUF938 PF06080.12 ORY45502.1 - 1.9e-30 106.1 0.9 3e-29 102.3 0.9 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 ORY45502.1 - 2.3e-05 25.0 0.0 3.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY45502.1 - 0.00022 21.1 0.0 0.00027 20.8 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY45502.1 - 0.00042 20.9 0.0 0.00059 20.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 ORY45502.1 - 0.054 13.0 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.14 ORY45502.1 - 0.074 12.6 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase small domain TPT PF03151.16 ORY45503.1 - 1.8e-12 47.2 16.2 2.1e-09 37.1 16.2 2.9 1 1 0 1 1 1 1 Triose-phosphate Transporter family FAD_binding_3 PF01494.19 ORY45503.1 - 6.4e-07 28.9 0.0 1.2e-06 28.0 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain Anoctamin PF04547.12 ORY45503.1 - 0.00045 19.2 1.2 0.00045 19.2 1.2 2.0 2 0 0 2 2 2 1 Calcium-activated chloride channel FAD_binding_3 PF01494.19 ORY45504.1 - 1.3e-12 47.6 0.6 5.9e-12 45.5 0.6 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY45504.1 - 6.2e-06 25.6 2.0 0.025 13.8 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY45504.1 - 0.0017 18.0 3.3 0.0037 16.9 2.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY45504.1 - 0.0044 17.2 1.5 0.0073 16.5 0.3 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY45504.1 - 0.017 15.6 0.5 0.32 11.6 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY45504.1 - 0.31 10.1 2.3 0.68 8.9 2.3 1.6 1 0 0 1 1 1 0 FAD binding domain ECH_1 PF00378.20 ORY45505.1 - 2e-25 89.5 0.0 2.6e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY45505.1 - 9.8e-09 35.1 0.0 1.6e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase FAD_binding_3 PF01494.19 ORY45506.1 - 1.3e-19 70.7 0.3 1.3e-18 67.3 0.3 2.5 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 ORY45506.1 - 0.0059 15.7 0.0 0.063 12.3 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 ORY45506.1 - 0.046 14.0 0.4 0.13 12.5 0.4 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain p25-alpha PF05517.12 ORY45507.1 - 2.4e-38 131.7 0.0 5.4e-28 98.1 0.0 2.3 2 1 0 2 2 2 2 p25-alpha Mito_carr PF00153.27 ORY45508.1 - 3.7e-62 206.3 6.7 1.3e-21 76.3 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 ORY45510.1 - 3.9e-49 167.4 0.3 9.3e-26 90.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY45510.1 - 1.3e-27 96.7 1.2 2.3e-13 50.0 0.0 2.6 2 1 1 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY45510.1 - 0.042 13.2 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 ORY45511.1 - 1.2e-58 198.5 0.0 1.4e-58 198.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY45511.1 - 6.9e-39 133.7 0.0 8.4e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY45511.1 - 6.6e-06 25.6 0.0 9.4e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY45511.1 - 0.0043 16.0 0.1 0.0066 15.4 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 ORY45511.1 - 0.0072 15.1 0.0 0.0088 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY45511.1 - 0.012 15.5 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 ORY45511.1 - 0.058 12.4 0.0 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RTC PF01137.21 ORY45512.1 - 9.5e-46 155.8 0.0 1.2e-45 155.4 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 ORY45512.1 - 1.9e-31 108.6 0.0 1.4e-30 105.8 0.0 2.1 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain AA_permease PF00324.21 ORY45513.1 - 7.4e-41 140.2 20.5 8.7e-41 140.0 20.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY45513.1 - 4.3e-11 42.3 20.1 5e-11 42.1 20.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY45514.1 - 2e-28 99.3 12.2 2.4e-28 99.0 12.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY45514.1 - 6.2e-10 38.5 12.2 7.6e-10 38.2 12.2 1.2 1 0 0 1 1 1 1 Amino acid permease Fringe PF02434.16 ORY45516.1 - 0.13 11.6 0.1 0.16 11.3 0.1 1.1 1 0 0 1 1 1 0 Fringe-like CBM9_1 PF06452.11 ORY45518.1 - 4.8e-11 42.9 0.0 9.7e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate family 9 binding domain-like CBM9_2 PF16011.5 ORY45518.1 - 9.5e-05 22.2 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate-binding family 9 NTP_transferase PF00483.23 ORY45520.1 - 1.8e-05 24.4 0.0 0.00017 21.3 0.0 2.1 2 1 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 ORY45520.1 - 0.00032 21.1 0.0 0.00042 20.7 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain UL2 PF08196.11 ORY45521.1 - 0.039 13.9 0.3 0.07 13.1 0.3 1.4 1 0 0 1 1 1 0 UL2 protein DUF5484 PF17583.2 ORY45521.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5484) MBOAT_2 PF13813.6 ORY45522.1 - 2.7e-09 37.1 5.0 6.9e-09 35.9 5.0 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family OPT PF03169.15 ORY45524.1 - 2.2e-112 376.8 56.2 2.7e-112 376.5 56.2 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2109 PF09882.9 ORY45524.1 - 0.63 10.1 5.0 0.56 10.2 0.8 2.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) Alpha_kinase PF02816.18 ORY45525.1 - 1.4e-38 132.8 4.1 6.8e-25 88.3 0.2 2.6 3 0 0 3 3 3 2 Alpha-kinase family VWA_2 PF13519.6 ORY45525.1 - 3.9e-07 30.7 0.1 1.1e-06 29.2 0.1 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 ORY45525.1 - 0.0095 16.2 0.3 0.024 14.9 0.3 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain MBOAT_2 PF13813.6 ORY45526.1 - 2.6e-11 43.6 0.3 6.8e-11 42.3 0.3 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MBOAT_2 PF13813.6 ORY45527.1 - 4.1e-10 39.8 0.3 1e-09 38.5 0.3 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family bZIP_2 PF07716.15 ORY45530.1 - 0.0081 16.2 8.1 0.0081 16.2 8.1 2.1 2 1 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 ORY45530.1 - 0.48 10.6 15.7 0.086 13.0 11.2 1.8 2 0 0 2 2 2 0 bZIP transcription factor bZIP_1 PF00170.21 ORY45531.1 - 0.0088 16.1 5.5 0.0088 16.1 5.5 2.3 2 0 0 2 2 2 1 bZIP transcription factor DUF1529 PF07485.11 ORY45531.1 - 0.084 12.8 0.0 9.2 6.2 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1259) DUF733 PF05306.11 ORY45531.1 - 6.2 7.2 8.2 2.7 8.4 2.8 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF733) bZIP_1 PF00170.21 ORY45532.1 - 1.6e-06 28.1 6.1 2.6e-06 27.4 6.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 ORY45532.1 - 0.025 14.6 9.6 0.043 13.9 9.6 1.4 1 1 0 1 1 1 0 Basic region leucine zipper DUF4683 PF15735.5 ORY45533.1 - 0.11 12.1 0.1 0.13 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4683) bZIP_1 PF00170.21 ORY45534.1 - 4.7e-05 23.4 9.3 4.7e-05 23.4 9.3 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORY45534.1 - 0.0018 18.3 15.4 0.0059 16.7 8.0 2.4 2 0 0 2 2 2 2 Basic region leucine zipper DUF3287 PF11690.8 ORY45534.1 - 0.017 14.9 0.8 0.035 13.8 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) TSC22 PF01166.18 ORY45534.1 - 0.24 11.7 4.6 2 8.8 0.6 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family MPS2 PF17060.5 ORY45534.1 - 0.61 9.3 3.9 0.88 8.8 3.9 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 GATA PF00320.27 ORY45539.1 - 2e-14 52.9 7.6 3.6e-14 52.1 7.6 1.5 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.18 ORY45539.1 - 0.033 14.3 0.9 0.045 13.8 0.9 1.2 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf DUF2387 PF09526.10 ORY45539.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) NMD3 PF04981.13 ORY45539.1 - 0.14 11.6 0.1 0.17 11.3 0.1 1.1 1 0 0 1 1 1 0 NMD3 family FAD_binding_3 PF01494.19 ORY45541.1 - 1.9e-23 83.3 0.3 3e-22 79.4 0.3 2.5 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 ORY45541.1 - 3.8e-05 22.9 0.0 0.00019 20.6 0.0 1.9 1 1 0 1 1 1 1 Squalene epoxidase DAO PF01266.24 ORY45541.1 - 0.00033 20.4 3.7 0.13 11.8 2.7 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 ORY45541.1 - 0.0015 19.0 0.1 0.46 11.1 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY45541.1 - 0.012 14.9 0.8 2.3 7.4 0.8 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY45541.1 - 0.027 13.7 0.0 5.4 6.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY45541.1 - 0.031 14.5 1.5 0.091 13.0 1.5 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORY45541.1 - 0.68 8.9 6.0 1.3 8.0 5.4 1.7 1 1 1 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.19 ORY45542.1 - 3.1e-19 69.4 0.3 2.1e-08 33.8 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 ORY45542.1 - 0.00043 19.4 0.0 0.0016 17.6 0.0 1.8 2 0 0 2 2 2 1 Squalene epoxidase FAD_binding_2 PF00890.24 ORY45542.1 - 0.1 11.7 2.6 0.16 11.0 2.6 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 ORY45542.1 - 0.13 12.9 0.3 32 5.2 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 ORY45542.1 - 0.16 11.2 0.4 7.4 5.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY45542.1 - 0.17 12.2 1.6 0.25 11.6 0.5 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GATA PF00320.27 ORY45543.1 - 2.4e-14 52.6 2.0 3.8e-14 52.0 2.0 1.3 1 0 0 1 1 1 1 GATA zinc finger DZR PF12773.7 ORY45543.1 - 0.022 14.8 0.6 0.057 13.5 0.6 1.6 1 1 0 1 1 1 0 Double zinc ribbon Nucleo_P87 PF07267.11 ORY45543.1 - 0.12 11.2 0.3 0.14 11.0 0.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 ArfGap PF01412.18 ORY45543.1 - 0.15 12.1 2.0 0.29 11.2 2.0 1.5 1 1 0 1 1 1 0 Putative GTPase activating protein for Arf GATA PF00320.27 ORY45544.1 - 8.5e-15 54.1 2.3 1.3e-14 53.5 2.3 1.3 1 0 0 1 1 1 1 GATA zinc finger eIF-5_eIF-2B PF01873.17 ORY45544.1 - 0.004 17.0 0.6 0.008 16.0 0.6 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 OrfB_Zn_ribbon PF07282.11 ORY45544.1 - 0.14 12.1 1.3 0.23 11.4 1.3 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Chlam_PMP PF02415.17 ORY45544.1 - 0.14 12.7 0.7 0.48 11.0 0.7 2.1 1 1 0 1 1 1 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DUF1752 PF08550.10 ORY45545.1 - 2.3e-11 43.3 0.2 4.4e-11 42.4 0.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) GATA PF00320.27 ORY45546.1 - 1.6e-23 82.0 25.6 3.7e-13 48.8 3.8 2.8 3 0 0 3 3 3 2 GATA zinc finger ArfGap PF01412.18 ORY45546.1 - 3.4e-05 23.9 3.5 0.091 12.8 0.2 2.3 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf TF_Zn_Ribbon PF08271.12 ORY45546.1 - 0.00032 20.1 7.6 0.005 16.3 0.6 2.2 2 0 0 2 2 2 2 TFIIB zinc-binding DZR PF12773.7 ORY45546.1 - 0.17 11.9 12.9 3.6 7.7 12.8 2.7 1 1 1 2 2 2 0 Double zinc ribbon OTT_1508_deam PF14441.6 ORY45546.1 - 0.27 11.3 4.6 0.48 10.5 0.2 2.7 1 1 1 2 2 2 0 OTT_1508-like deaminase zf-RRPl_C4 PF17026.5 ORY45546.1 - 0.85 9.7 4.6 12 6.0 5.4 2.0 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type Zn-ribbon_8 PF09723.10 ORY45546.1 - 2.5 8.3 9.8 4.9 7.3 0.4 3.1 2 1 0 3 3 3 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.17 ORY45546.1 - 4.3 7.2 9.7 2 8.3 1.2 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 NMD3 PF04981.13 ORY45546.1 - 5.1 6.5 8.0 6.2 6.2 1.1 2.1 1 1 1 2 2 2 0 NMD3 family Auto_anti-p27 PF06677.12 ORY45546.1 - 5.9 7.1 13.9 1.3 9.2 0.9 2.7 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF1752 PF08550.10 ORY45547.1 - 1e-08 34.9 0.1 2.6e-08 33.6 0.1 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) GATA PF00320.27 ORY45547.1 - 2.2e-07 30.4 2.9 3.9e-07 29.5 2.9 1.4 1 0 0 1 1 1 1 GATA zinc finger CDRT4 PF15213.6 ORY45547.1 - 1.3 9.7 11.4 0.99 10.0 2.1 3.2 3 0 0 3 3 3 0 CMT1A duplicated region transcript 4 protein DUF824 PF05688.11 ORY45547.1 - 8.4 6.3 6.8 0.47 10.3 0.2 2.3 3 0 0 3 3 3 0 Salmonella repeat of unknown function (DUF824) SNF2_N PF00176.23 ORY45548.1 - 6.1e-19 67.9 0.0 7.4e-11 41.4 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain MBD PF01429.19 ORY45548.1 - 2.4e-06 27.1 0.0 7.8e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 Methyl-CpG binding domain Helicase_C PF00271.31 ORY45548.1 - 0.0008 19.7 0.1 0.003 17.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Zn_clus PF00172.18 ORY45550.1 - 0.0014 18.7 1.7 0.0022 18.1 1.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_membrane PF00664.23 ORY45551.1 - 3.7e-56 190.8 46.3 1.2e-36 126.8 17.6 3.0 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY45551.1 - 1.6e-49 167.9 3.2 5.4e-29 101.4 0.1 3.1 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 ORY45551.1 - 7.7e-09 35.3 9.4 0.0053 16.2 1.3 4.4 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY45551.1 - 5.9e-06 26.4 3.5 0.1 12.7 0.0 3.6 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY45551.1 - 6.1e-05 23.0 0.9 0.019 14.9 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase MTABC_N PF16185.5 ORY45551.1 - 0.00012 21.7 6.5 0.00048 19.7 6.5 2.0 1 0 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region AAA_21 PF13304.6 ORY45551.1 - 0.00092 19.1 0.4 11 5.7 0.0 3.4 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 ORY45551.1 - 0.0057 16.9 1.6 14 5.9 0.1 4.2 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 ORY45551.1 - 0.0088 15.6 0.2 0.24 10.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 ORY45551.1 - 0.012 15.4 3.3 2.9 7.7 0.3 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY45551.1 - 0.023 15.1 0.2 8 6.8 0.0 3.2 3 0 0 3 3 3 0 AAA ATPase domain Dynamin_N PF00350.23 ORY45551.1 - 0.038 14.0 4.5 0.063 13.3 0.4 2.6 2 1 0 2 2 2 0 Dynamin family DUF5021 PF16424.5 ORY45551.1 - 0.043 13.7 0.1 0.096 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5021) AAA_7 PF12775.7 ORY45551.1 - 0.047 13.2 0.2 1.9 7.9 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 ORY45551.1 - 0.073 13.2 3.8 2.1 8.4 0.3 2.8 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 ORY45551.1 - 0.073 13.3 0.4 11 6.4 0.0 2.8 2 1 0 2 2 2 0 AAA domain AA_permease PF00324.21 ORY45552.1 - 8.9e-109 364.2 38.6 1.1e-108 363.9 38.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY45552.1 - 2.4e-37 128.8 44.0 3.1e-37 128.4 44.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY45553.1 - 7.4e-92 308.4 41.4 1.8e-80 270.9 25.9 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 ORY45553.1 - 4.2e-29 101.6 27.5 4.2e-29 101.6 27.5 2.2 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.21 ORY45554.1 - 4.4e-103 345.4 39.5 5.4e-103 345.2 39.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY45554.1 - 1.2e-35 123.2 43.1 1.6e-35 122.8 43.1 1.0 1 0 0 1 1 1 1 Amino acid permease TrbE PF11100.8 ORY45554.1 - 0.11 12.8 3.3 0.11 12.7 0.3 2.6 2 0 0 2 2 2 0 Conjugal transfer protein TrbE SAP PF02037.27 ORY45555.1 - 6e-08 32.3 0.1 1.7e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 SAP domain BK_channel_a PF03493.18 ORY45555.1 - 0.023 14.9 0.5 0.06 13.5 0.5 1.6 1 0 0 1 1 1 0 Calcium-activated BK potassium channel alpha subunit PhoPQ_related PF10142.9 ORY45555.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein MBOAT_2 PF13813.6 ORY45556.1 - 0.00017 21.8 0.2 0.00039 20.6 0.2 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family MBOAT_2 PF13813.6 ORY45557.1 - 6.8e-06 26.3 0.5 1.3e-05 25.3 0.5 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF3774 PF12609.8 ORY45557.1 - 0.16 13.0 1.0 0.33 12.0 0.1 1.8 2 0 0 2 2 2 0 Wound-induced protein WBP-1 PF11669.8 ORY45559.1 - 0.052 14.2 1.3 0.069 13.8 1.3 1.5 1 1 0 1 1 1 0 WW domain-binding protein 1 EphA2_TM PF14575.6 ORY45559.1 - 0.084 13.8 0.0 0.096 13.6 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain MBOAT_2 PF13813.6 ORY45560.1 - 0.005 17.1 0.7 0.005 17.1 0.7 2.5 2 1 0 2 2 2 1 Membrane bound O-acyl transferase family MBOAT_2 PF13813.6 ORY45561.1 - 0.0069 16.6 0.1 0.021 15.1 0.1 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Piwi PF02171.17 ORY45562.1 - 1.9e-68 231.0 0.0 4.2e-68 229.8 0.0 1.5 1 1 0 1 1 1 1 Piwi domain PAZ PF02170.22 ORY45562.1 - 4.6e-23 81.5 0.0 7.8e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoN PF16486.5 ORY45562.1 - 1.4e-21 77.6 0.0 3.2e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoMid PF16487.5 ORY45562.1 - 3.8e-12 46.3 0.2 1.7e-11 44.2 0.0 2.1 3 0 0 3 3 3 1 Mid domain of argonaute ArgoL2 PF16488.5 ORY45562.1 - 0.017 15.5 0.0 0.053 13.9 0.0 1.9 1 0 0 1 1 1 0 Argonaute linker 2 domain AAA_19 PF13245.6 ORY45563.1 - 0.0085 16.4 0.0 0.1 12.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain SGIII PF15467.6 ORY45563.1 - 0.015 14.5 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Secretogranin-3 ResIII PF04851.15 ORY45563.1 - 0.02 14.9 0.0 0.049 13.6 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 ORY45563.1 - 0.033 13.9 0.0 0.46 10.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ORY45563.1 - 0.065 13.5 0.1 0.72 10.1 0.1 2.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY45563.1 - 0.18 12.2 0.0 0.47 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Dicty_REP PF05086.12 ORY45565.1 - 3.5 5.5 5.9 3.5 5.5 5.9 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NIF PF03031.18 ORY45566.1 - 4.5e-54 182.4 0.0 5.5e-54 182.2 0.0 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.7 ORY45566.1 - 0.0028 18.1 0.1 0.027 14.9 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase MBOAT_2 PF13813.6 ORY45567.1 - 5.1e-05 23.5 0.5 5.1e-05 23.5 0.5 2.1 2 1 0 2 2 2 1 Membrane bound O-acyl transferase family PGA2 PF07543.12 ORY45567.1 - 0.12 12.4 1.3 0.54 10.2 0.3 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 F-box-like PF12937.7 ORY45568.1 - 0.0001 22.1 0.2 0.00021 21.1 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY45568.1 - 0.011 15.6 0.1 0.027 14.3 0.1 1.7 1 0 0 1 1 1 0 F-box domain SPG48 PF14764.6 ORY45568.1 - 0.084 13.3 0.0 0.24 11.9 0.0 1.7 1 0 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking AA_permease PF00324.21 ORY45570.1 - 7.8e-110 367.7 39.0 9.4e-110 367.4 39.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY45570.1 - 3.5e-36 124.9 44.6 4.5e-36 124.6 44.6 1.1 1 0 0 1 1 1 1 Amino acid permease Fucose_iso_C PF02952.17 ORY45571.1 - 2.9 7.6 5.1 0.7 9.6 1.3 1.9 2 0 0 2 2 2 0 L-fucose isomerase, C-terminal domain Grg1 PF11034.8 ORY45571.1 - 3.7 7.8 8.6 7.7 6.8 0.6 3.4 3 0 0 3 3 3 0 Glucose-repressible protein Grg1 FYVE PF01363.21 ORY45572.1 - 6.9e-20 71.0 7.7 1e-19 70.4 7.7 1.3 1 0 0 1 1 1 1 FYVE zinc finger CENP-B_dimeris PF09026.10 ORY45572.1 - 0.25 11.7 6.3 0.45 10.9 6.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf_C2HC_14 PF18574.1 ORY45572.1 - 0.3 10.9 4.2 0.65 9.8 4.2 1.5 1 0 0 1 1 1 0 C2HC Zing finger domain zf-AN1 PF01428.16 ORY45572.1 - 0.56 10.4 6.6 1.7 8.9 6.7 1.8 1 1 0 1 1 1 0 AN1-like Zinc finger FYVE_2 PF02318.16 ORY45572.1 - 2.6 8.3 6.0 10 6.3 6.2 1.7 1 1 0 1 1 1 0 FYVE-type zinc finger Fungal_trans PF04082.18 ORY45573.1 - 0.00013 21.1 0.1 0.00025 20.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY45573.1 - 0.23 11.6 3.0 0.57 10.3 3.0 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY45574.1 - 0.041 12.9 0.3 0.067 12.2 0.3 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain ABC_membrane PF00664.23 ORY45576.1 - 1.1e-55 189.2 34.6 1.1e-35 123.6 13.9 2.8 3 1 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY45576.1 - 2.4e-50 170.6 2.7 3e-29 102.3 0.1 3.2 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 ORY45576.1 - 4.4e-07 29.5 15.7 0.0087 15.5 1.5 4.5 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY45576.1 - 5.1e-07 29.8 0.5 0.033 14.3 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase MTABC_N PF16185.5 ORY45576.1 - 3.1e-05 23.6 7.3 3.1e-05 23.6 7.3 2.7 2 0 0 2 2 2 1 Mitochondrial ABC-transporter N-terminal five TM region RsgA_GTPase PF03193.16 ORY45576.1 - 7.9e-05 22.6 0.9 0.027 14.4 0.1 2.6 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 ORY45576.1 - 0.0011 18.9 2.5 3.5 7.4 0.3 3.3 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 ORY45576.1 - 0.0014 18.7 1.5 0.016 15.3 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 ORY45576.1 - 0.0035 17.1 1.5 2.7 7.8 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 ORY45576.1 - 0.032 13.8 0.2 0.45 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 ORY45576.1 - 0.051 13.8 0.8 14 5.9 0.1 3.9 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 ORY45576.1 - 0.053 13.0 0.1 2.2 7.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 ORY45576.1 - 0.084 12.0 0.6 5.5 6.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IIGP PF05049.13 ORY45576.1 - 0.11 11.6 2.8 0.56 9.2 0.1 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 ORY45576.1 - 0.13 12.6 0.3 19 5.6 0.1 2.8 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 ORY45576.1 - 0.13 12.3 5.8 2.1 8.4 0.3 2.7 3 0 0 3 3 2 0 Helicase HerA, central domain CAP PF00188.26 ORY45577.1 - 2.8e-11 44.3 0.4 4.9e-11 43.5 0.0 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family TMEM154 PF15102.6 ORY45577.1 - 0.00017 21.5 0.3 0.00017 21.5 0.3 2.4 1 1 1 2 2 2 1 TMEM154 protein family MGC-24 PF05283.11 ORY45577.1 - 0.00026 21.5 8.8 0.00026 21.5 8.8 2.1 2 1 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF1180 PF06679.12 ORY45577.1 - 0.00083 19.8 0.8 0.00083 19.8 0.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1180) DUF5305 PF17231.2 ORY45577.1 - 0.0015 18.0 2.5 0.0022 17.4 2.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Adeno_E3_CR2 PF02439.15 ORY45577.1 - 0.0092 15.7 6.3 0.016 14.9 6.3 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Stevor PF17410.2 ORY45577.1 - 0.014 14.9 3.8 0.03 13.9 3.8 1.5 1 1 0 1 1 1 0 Subtelomeric Variable Open Reading frame Pex14_N PF04695.13 ORY45577.1 - 0.021 15.5 0.9 0.04 14.6 0.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AJAP1_PANP_C PF15298.6 ORY45577.1 - 0.025 14.8 9.8 0.059 13.6 9.8 1.6 1 0 0 1 1 1 0 AJAP1/PANP C-terminus LapA_dom PF06305.11 ORY45577.1 - 0.073 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF2207 PF09972.9 ORY45577.1 - 0.074 11.8 0.0 0.095 11.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glycophorin_A PF01102.18 ORY45577.1 - 0.1 12.9 7.4 0.32 11.2 7.4 1.9 1 1 0 1 1 1 0 Glycophorin A Pox_A14 PF05767.12 ORY45577.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF5534 PF17686.1 ORY45577.1 - 0.16 12.2 0.3 0.25 11.6 0.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5534) MULE PF10551.9 ORY45578.1 - 1.1e-10 41.7 0.0 6.6e-10 39.3 0.0 2.4 2 0 0 2 2 2 1 MULE transposase domain Imm3 PF14425.6 ORY45578.1 - 0.011 15.8 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 Immunity protein Imm3 AAA_30 PF13604.6 ORY45579.1 - 0.00085 19.1 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 ORY45579.1 - 0.0023 18.4 0.0 0.0047 17.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF3987 PF13148.6 ORY45579.1 - 0.0024 16.9 0.1 2.2 7.2 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF3987) MMR_HSR1 PF01926.23 ORY45579.1 - 0.004 17.2 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 ORY45579.1 - 0.0096 16.3 0.0 0.21 12.0 0.0 2.5 1 1 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 ORY45579.1 - 0.012 15.9 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORY45579.1 - 0.012 16.2 0.0 0.023 15.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY45579.1 - 0.015 15.7 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 ORY45579.1 - 0.018 14.8 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 ORY45579.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 ORY45579.1 - 0.07 13.3 0.1 0.36 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORY45579.1 - 0.089 12.3 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 ORY45579.1 - 0.099 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 ORY45579.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 ORY45579.1 - 0.19 10.9 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 ORY45579.1 - 0.21 11.5 0.0 0.61 10.0 0.1 1.7 2 0 0 2 2 2 0 NTPase ABC_membrane PF00664.23 ORY45580.1 - 1.7e-57 195.1 49.0 1.6e-36 126.4 18.4 2.6 3 0 0 3 3 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY45580.1 - 8.2e-50 168.9 1.0 5.2e-29 101.5 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY45580.1 - 6.4e-09 35.6 9.4 0.0078 15.7 1.3 4.4 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY45580.1 - 1.3e-06 28.5 0.4 0.098 12.7 0.1 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY45580.1 - 9.6e-05 22.3 1.5 0.016 15.1 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 ORY45580.1 - 0.00078 19.3 0.4 9.5 5.9 0.0 3.5 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 ORY45580.1 - 0.0026 17.8 0.8 0.051 13.6 0.0 2.5 2 0 0 2 2 2 1 Dynamin family AAA_25 PF13481.6 ORY45580.1 - 0.013 15.1 0.2 0.22 11.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 ORY45580.1 - 0.014 15.2 3.5 3 7.7 0.3 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY45580.1 - 0.014 15.8 0.2 7.5 6.9 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain DUF87 PF01935.17 ORY45580.1 - 0.027 14.6 4.0 0.65 10.1 0.3 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 ORY45580.1 - 0.035 13.8 0.1 3.4 7.3 0.0 2.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_7 PF12775.7 ORY45580.1 - 0.039 13.5 0.2 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_22 PF13401.6 ORY45580.1 - 0.1 12.9 1.1 10 6.4 0.1 2.7 3 0 0 3 3 2 0 AAA domain Sigma54_activat PF00158.26 ORY45580.1 - 0.12 12.1 0.1 3.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain BBP1_N PF15271.6 ORY45581.1 - 0.0014 19.4 5.3 0.027 15.3 0.9 2.5 2 0 0 2 2 2 2 Spindle pole body component BBP1, Mps2-binding protein AAA_2 PF07724.14 ORY45581.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) TFIIA PF03153.13 ORY45581.1 - 2.4 8.1 52.3 0.13 12.2 26.6 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit BAF250_C PF12031.8 ORY45582.1 - 7.2e-11 41.9 2.0 2.6e-10 40.1 2.0 1.8 1 1 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa Ferric_reduct PF01794.19 ORY45583.1 - 1.2e-17 64.2 7.4 2.1e-17 63.4 7.4 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ORY45583.1 - 3.8e-07 30.2 0.0 1e-06 28.8 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.12 ORY45583.1 - 1.8e-05 24.9 0.0 3.8e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain RNase_P_p30 PF01876.16 ORY45584.1 - 1.5e-52 178.2 0.5 1.7e-52 178.0 0.5 1.0 1 0 0 1 1 1 1 RNase P subunit p30 SlyX PF04102.12 ORY45585.1 - 0.012 16.2 1.0 0.36 11.5 0.0 3.1 3 0 0 3 3 3 0 SlyX CCDC66 PF15236.6 ORY45586.1 - 5.3e-07 29.6 24.0 5.3e-07 29.6 24.0 2.2 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 66 DUF4055 PF13264.6 ORY45586.1 - 0.18 11.9 2.6 0.33 11.1 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) FAST_2 PF08368.12 ORY45586.1 - 0.76 10.6 3.2 16 6.3 0.2 2.4 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 2 TFIIA PF03153.13 ORY45586.1 - 5.1 7.0 22.8 6.3 6.7 22.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ICL PF00463.21 ORY45588.1 - 9.4e-243 806.5 2.1 1.6e-242 805.7 2.1 1.3 1 1 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 ORY45588.1 - 1.1e-07 31.6 0.1 1.9e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase RFC1 PF08519.12 ORY45588.1 - 0.099 12.8 0.0 0.6 10.3 0.1 2.1 2 0 0 2 2 2 0 Replication factor RFC1 C terminal domain PDEase_I PF00233.19 ORY45590.1 - 2.8e-50 171.3 0.0 1.9e-49 168.5 0.0 2.3 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Acetyltransf_7 PF13508.7 ORY45591.1 - 3.5e-05 24.1 0.1 0.00021 21.6 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY45591.1 - 3.8e-05 23.9 0.0 0.00035 20.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY45591.1 - 0.0042 17.0 0.1 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY45591.1 - 0.0097 16.0 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase 7tm_2 PF00002.24 ORY45592.1 - 8e-09 35.1 13.2 1.3e-08 34.5 13.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 ORY45592.1 - 3e-08 33.3 11.2 4.1e-08 32.9 11.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 ORY45592.1 - 1.6e-05 24.2 9.4 1.6e-05 24.2 9.4 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Chordopox_G3 PF06129.12 ORY45592.1 - 0.0061 17.3 0.1 0.014 16.1 0.1 1.6 1 1 0 1 1 1 1 Chordopoxvirus G3 protein Tmemb_18A PF09771.9 ORY45592.1 - 0.014 15.8 1.0 0.014 15.8 1.0 2.6 3 0 0 3 3 3 0 Transmembrane protein 188 DUF4834 PF16118.5 ORY45592.1 - 0.025 15.5 0.1 0.14 13.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Orbi_VP4 PF05059.12 ORY45592.1 - 0.25 9.3 1.4 0.35 8.9 1.4 1.1 1 0 0 1 1 1 0 Orbivirus VP4 core protein Ocular_alb PF02101.15 ORY45592.1 - 2.3 7.1 12.5 4.2 6.2 12.5 1.5 1 0 0 1 1 1 0 Ocular albinism type 1 protein ABC_tran PF00005.27 ORY45593.1 - 1.6e-41 142.0 0.3 6.1e-20 72.1 0.0 3.3 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 ORY45593.1 - 7.5e-18 65.4 1.6 4e-05 23.6 0.0 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ORY45593.1 - 7.1e-11 42.4 0.4 0.00017 21.4 0.0 4.9 3 1 0 3 3 3 1 AAA ATPase domain SMC_N PF02463.19 ORY45593.1 - 6.3e-09 35.6 9.9 0.49 9.8 0.0 5.1 5 0 0 5 5 5 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY45593.1 - 3.7e-08 33.0 1.8 0.0091 15.7 0.1 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain ABC_tran_Xtn PF12848.7 ORY45593.1 - 5.6e-06 26.3 12.5 5.6e-06 26.3 12.5 2.7 3 0 0 3 3 2 1 ABC transporter AAA_22 PF13401.6 ORY45593.1 - 1.1e-05 25.7 0.1 0.063 13.5 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_27 PF13514.6 ORY45593.1 - 0.00021 20.9 4.3 0.18 11.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 ORY45593.1 - 0.00071 19.4 0.0 0.13 12.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 ORY45593.1 - 0.0009 19.8 0.8 0.042 14.3 0.1 4.5 4 1 0 4 4 4 2 AAA domain AAA_18 PF13238.6 ORY45593.1 - 0.0012 19.4 0.6 0.081 13.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 ORY45593.1 - 0.0016 18.4 4.7 0.016 15.1 0.0 3.2 3 0 0 3 3 3 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 ORY45593.1 - 0.0017 17.8 0.0 0.068 12.5 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.6 ORY45593.1 - 0.0047 16.5 0.0 2.5 7.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 ORY45593.1 - 0.0061 16.6 0.8 0.051 13.6 0.0 2.7 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_33 PF13671.6 ORY45593.1 - 0.0062 16.7 0.0 0.23 11.6 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 ORY45593.1 - 0.02 15.3 0.4 2.8 8.4 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 ORY45593.1 - 0.023 14.6 0.3 1.9 8.4 0.0 2.8 3 0 0 3 3 3 0 NACHT domain AAA_16 PF13191.6 ORY45593.1 - 0.023 15.1 0.0 0.64 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.22 ORY45593.1 - 0.035 14.5 0.0 1.4 9.3 0.0 2.6 2 0 0 2 2 2 0 RNA helicase MukB PF04310.12 ORY45593.1 - 0.037 13.8 0.1 7.1 6.4 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal NTPase_1 PF03266.15 ORY45593.1 - 0.042 13.8 0.0 2 8.3 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.14 ORY45593.1 - 0.099 12.6 0.0 2.4 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 ORY45593.1 - 0.14 12.4 0.9 2.3 8.4 0.0 3.1 3 1 0 3 3 3 0 AAA domain DUF4999 PF16390.5 ORY45593.1 - 0.15 12.3 0.1 0.34 11.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 PF01935.17 ORY45593.1 - 0.24 11.5 7.6 14 5.7 0.2 3.6 3 0 0 3 3 3 0 Helicase HerA, central domain cobW PF02492.19 ORY45593.1 - 0.26 10.9 5.1 2 7.9 0.1 3.4 4 0 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain DDHD PF02862.17 ORY45593.1 - 0.73 10.0 4.5 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 DDHD domain STAT_bind PF02864.15 ORY45593.1 - 0.98 10.0 4.9 2.5 8.7 4.9 1.7 1 0 0 1 1 1 0 STAT protein, DNA binding domain TMPIT PF07851.13 ORY45593.1 - 4.2 6.5 8.1 8 5.6 8.1 1.4 1 0 0 1 1 1 0 TMPIT-like protein GAGA_bind PF06217.12 ORY45593.1 - 8.9 6.5 14.0 8.6 6.5 1.5 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family HSP70 PF00012.20 ORY45594.1 - 7e-257 853.4 13.6 8e-257 853.2 13.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 ORY45594.1 - 9.9e-17 60.7 0.5 3.2e-15 55.8 0.2 2.3 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 ORY45594.1 - 0.0042 16.1 0.7 0.029 13.4 0.4 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 ORY45594.1 - 0.0049 16.2 4.4 0.72 9.1 0.3 3.2 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase FtsA PF14450.6 ORY45594.1 - 0.01 16.2 6.8 2.4 8.6 0.2 4.1 3 2 0 3 3 3 0 Cell division protein FtsA DUF4624 PF15417.6 ORY45594.1 - 0.094 12.5 1.1 2.1 8.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4624) FGGY_C PF02782.16 ORY45594.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain FIVAR PF07554.13 ORY45594.1 - 2.2 9.1 9.7 1.6 9.6 6.3 2.6 3 0 0 3 3 3 0 FIVAR domain Radial_spoke_3 PF06098.11 ORY45594.1 - 2.7 7.2 11.1 0.057 12.7 3.5 2.0 3 0 0 3 3 3 0 Radial spoke protein 3 Spa1_C PF18218.1 ORY45594.1 - 7.9 7.0 7.3 5.3 7.5 2.9 2.6 2 1 1 3 3 3 0 Lantibiotic immunity protein Spa1 C-terminal domain Complex1_30kDa PF00329.19 ORY45595.1 - 1.2e-47 161.5 0.0 1.6e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit Ribosomal_L31 PF01197.18 ORY45596.1 - 3.3e-05 24.0 0.0 4.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L31 DUF5585 PF17823.1 ORY45599.1 - 0.0079 15.2 14.4 0.01 14.8 14.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5585) RMI1_N PF08585.12 ORY45599.1 - 0.036 13.8 0.2 0.054 13.3 0.2 1.3 1 0 0 1 1 1 0 RecQ mediated genome instability protein Put_Phosphatase PF06888.12 ORY45599.1 - 0.045 13.1 0.0 0.061 12.7 0.0 1.1 1 0 0 1 1 1 0 Putative Phosphatase Transposase_21 PF02992.14 ORY45600.1 - 0.026 13.8 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Transposase family tnp2 Siva PF05458.12 ORY45600.1 - 0.081 12.6 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Cd27 binding protein (Siva) WD40 PF00400.32 ORY45601.1 - 2.8e-25 88.1 13.3 3.2e-07 30.9 0.2 6.8 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY45601.1 - 2.1e-09 37.5 1.3 0.19 12.0 0.1 4.7 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY45601.1 - 0.00017 21.5 0.2 0.086 12.7 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 ORY45601.1 - 0.012 14.3 1.1 0.34 9.5 0.1 2.4 1 1 1 2 2 2 0 Nucleoporin Nup120/160 TRAM_2 PF18693.1 ORY45601.1 - 0.03 14.5 0.0 0.1 12.8 0.0 1.9 1 0 0 1 1 1 0 TRAM domain NIF PF03031.18 ORY45601.1 - 0.043 13.6 0.1 0.09 12.5 0.1 1.6 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase MSA-2c PF12238.8 ORY45601.1 - 4.2 7.3 6.9 11 5.9 6.9 1.7 1 0 0 1 1 1 0 Merozoite surface antigen 2c PsbU PF06514.11 ORY45602.1 - 0.11 12.5 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) tRNA_m1G_MT PF01746.21 ORY45603.1 - 8.9e-26 90.8 0.1 5.4e-25 88.2 0.0 1.8 1 1 1 2 2 2 1 tRNA (Guanine-1)-methyltransferase Pox_Ag35 PF03286.14 ORY45603.1 - 8.2 6.2 19.2 0.11 12.3 10.0 2.1 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FAM176 PF14851.6 ORY45603.1 - 9.9 5.8 9.5 28 4.3 9.5 1.8 1 0 0 1 1 1 0 FAM176 family FCH PF00611.23 ORY45604.1 - 2e-14 53.6 0.5 2e-14 53.6 0.5 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF3091 PF11291.8 ORY45604.1 - 0.0072 16.5 0.4 0.0072 16.5 0.4 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF3091) Nup54 PF13874.6 ORY45604.1 - 0.91 9.6 4.0 2.4 8.3 1.8 2.5 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Adaptin_binding PF10199.9 ORY45604.1 - 4 8.1 5.9 3.1 8.4 0.0 3.0 4 0 0 4 4 4 0 Alpha and gamma adaptin binding protein p34 PI3K_P85_iSH2 PF16454.5 ORY45604.1 - 5.1 6.7 10.8 8.7 5.9 2.9 3.0 3 1 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain F_bP_aldolase PF01116.20 ORY45605.1 - 1.4e-88 297.0 0.1 1.7e-88 296.7 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Prion_bPrPp PF11587.8 ORY45606.1 - 0.22 11.4 1.7 0.5 10.3 1.7 1.6 1 0 0 1 1 1 0 Major prion protein bPrPp - N terminal Glycolytic PF00274.19 ORY45607.1 - 1.1e-167 557.2 0.0 1.3e-167 556.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I OMPdecase PF00215.24 ORY45608.1 - 2.1e-78 263.0 0.0 2.5e-78 262.8 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family P5CR_dimer PF14748.6 ORY45609.1 - 4.1e-34 116.9 1.3 9.4e-34 115.8 0.3 2.1 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 ORY45609.1 - 2.3e-14 53.7 1.0 2.3e-14 53.7 1.0 2.3 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Abhydrolase_1 PF00561.20 ORY45610.1 - 2e-14 53.9 0.1 4e-12 46.3 0.1 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY45610.1 - 1.3e-13 50.8 0.0 6.4e-10 38.7 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 BAAT_C PF08840.11 ORY45610.1 - 2.1e-08 34.4 0.2 6.2e-06 26.3 0.0 2.8 3 1 0 4 4 4 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.18 ORY45610.1 - 8.1e-07 28.9 0.0 7.6e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 ORY45610.1 - 2.7e-06 28.2 0.0 5e-05 24.0 0.0 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 ORY45610.1 - 3.4e-06 26.8 0.0 1.3e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 ORY45610.1 - 0.00015 21.5 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 ORY45610.1 - 0.0002 21.3 0.0 0.01 15.7 0.0 2.5 2 1 1 3 3 3 1 Phospholipase/Carboxylesterase AXE1 PF05448.12 ORY45610.1 - 0.00053 18.8 0.0 0.0017 17.1 0.0 1.6 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 ORY45610.1 - 0.0014 18.1 0.0 0.011 15.3 0.0 2.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 ORY45610.1 - 0.0032 17.3 0.0 0.0053 16.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.13 ORY45610.1 - 0.096 12.3 0.0 0.25 11.0 0.0 1.6 1 1 1 2 2 2 0 Serine hydrolase (FSH1) LIDHydrolase PF10230.9 ORY45610.1 - 0.14 11.7 0.0 2.5 7.6 0.0 2.1 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase DUF818 PF05677.12 ORY45610.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) PAF-AH_p_II PF03403.13 ORY45610.1 - 0.17 10.3 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF262 PF03235.14 ORY45611.1 - 1.3e-13 51.7 0.0 4.3e-13 49.9 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function DUF262 Tim44 PF04280.15 ORY45612.1 - 0.14 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Tim44-like domain DCP2 PF05026.13 ORY45614.1 - 7.9e-32 109.4 0.8 1.6e-31 108.4 0.8 1.6 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 ORY45614.1 - 1.2e-17 64.2 0.0 2.3e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 ORY45614.1 - 0.064 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain DVL PF08137.12 ORY45614.1 - 1.2 9.0 4.2 2.6 8.0 4.2 1.5 1 0 0 1 1 1 0 DVL family ADH_zinc_N PF00107.26 ORY45615.1 - 1.2e-25 90.0 0.0 2e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 ORY45615.1 - 2.1e-18 67.6 0.0 3.4e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY45615.1 - 2.9e-08 33.5 0.1 1.2e-06 28.4 0.0 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 ORY45615.1 - 0.089 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Peptidase_A2B PF12384.8 ORY45616.1 - 0.018 14.6 0.2 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 Ty3 transposon peptidase Pkinase PF00069.25 ORY45618.1 - 2.3e-31 109.1 0.0 3.4e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY45618.1 - 1.5e-15 57.2 0.0 2.3e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RA PF00788.23 ORY45618.1 - 8.9e-06 26.3 0.0 3.8e-05 24.2 0.0 2.0 2 0 0 2 2 2 1 Ras association (RalGDS/AF-6) domain PH PF00169.29 ORY45618.1 - 0.00014 22.4 0.0 0.00034 21.1 0.0 1.7 1 0 0 1 1 1 1 PH domain Pkinase PF00069.25 ORY45619.1 - 1.6e-18 67.1 0.0 1.8e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY45619.1 - 5.3e-11 42.3 0.0 6.9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY45619.1 - 0.094 12.0 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Bestrophin PF01062.21 ORY45620.1 - 3.9e-16 59.3 0.0 4.8e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Hemerythrin PF01814.23 ORY45620.1 - 0.027 15.1 0.1 0.041 14.5 0.1 1.2 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain Pyridoxal_deC PF00282.19 ORY45621.1 - 2.1e-79 266.9 0.0 2.9e-79 266.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF305 PF03713.13 ORY45621.1 - 0.051 13.7 0.4 0.12 12.5 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF305) Peptidase_S8 PF00082.22 ORY45622.1 - 6.2e-24 84.8 14.4 9.6e-23 80.9 14.4 2.2 1 1 0 1 1 1 1 Subtilase family DUF4336 PF14234.6 ORY45623.1 - 0.0078 15.4 0.0 1 8.5 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) Ca_hom_mod PF14798.6 ORY45624.1 - 1.3 8.1 5.3 1.3 8.1 3.0 2.2 1 1 1 2 2 2 0 Calcium homeostasis modulator Cdh1_DBD_1 PF18196.1 ORY45624.1 - 5 7.5 18.7 0.033 14.5 5.5 2.9 1 1 1 2 2 2 0 Chromodomain helicase DNA-binding domain 1 Guanylate_cyc PF00211.20 ORY45625.1 - 2.5e-41 141.3 0.0 3e-41 141.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 ORY45625.1 - 0.12 11.7 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Heme NO binding associated Nop14 PF04147.12 ORY45625.1 - 0.16 10.2 0.0 0.21 9.7 0.0 1.1 1 0 0 1 1 1 0 Nop14-like family zf-C2H2_11 PF16622.5 ORY45626.1 - 0.003 17.3 0.5 0.0053 16.5 0.5 1.4 1 0 0 1 1 1 1 zinc-finger C2H2-type zf-C2H2_4 PF13894.6 ORY45626.1 - 0.0043 17.8 2.7 0.0055 17.4 1.3 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY45626.1 - 0.0048 17.3 2.6 0.0093 16.4 1.0 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type Actin_micro PF17003.5 ORY45626.1 - 0.031 13.5 0.0 0.038 13.2 0.0 1.0 1 0 0 1 1 1 0 Putative actin-like family zf-C2H2_7 PF15269.6 ORY45626.1 - 0.04 14.0 0.5 0.072 13.2 0.5 1.4 1 0 0 1 1 1 0 Zinc-finger DpnI PF06044.12 ORY45626.1 - 0.044 13.4 0.0 0.45 10.1 0.0 2.1 1 1 1 2 2 2 0 Dam-replacing family zf-C2HE PF16278.5 ORY45626.1 - 0.055 13.9 0.3 0.1 13.1 0.3 1.4 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 ORY45626.1 - 0.091 13.1 1.3 0.19 12.1 0.5 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF629 PF04780.12 ORY45626.1 - 0.24 9.9 0.2 0.36 9.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF629) NAPRTase PF04095.16 ORY45627.1 - 6.9e-19 68.4 0.1 9.5e-19 68.0 0.1 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 ORY45627.1 - 1.2e-15 58.0 0.0 2.1e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NMO PF03060.15 ORY45628.1 - 5.1e-72 243.0 0.3 1.3e-71 241.7 0.3 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase FMN_dh PF01070.18 ORY45628.1 - 3.5e-09 36.2 0.6 6.7e-09 35.2 0.6 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 ORY45628.1 - 1.8e-07 30.5 0.1 2.3e-06 26.9 0.1 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.21 ORY45628.1 - 4.5e-07 29.4 0.1 8e-07 28.5 0.1 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 ORY45628.1 - 1.7e-05 24.1 0.1 5.6e-05 22.4 0.2 1.7 2 0 0 2 2 2 1 Conserved region in glutamate synthase NanE PF04131.14 ORY45628.1 - 2.2e-05 23.7 0.1 4.7e-05 22.7 0.1 1.5 1 1 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 ORY45628.1 - 0.00011 21.8 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 ORY45628.1 - 0.003 16.9 2.2 0.0043 16.4 1.6 1.5 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG PEP_hydrolase PF09370.10 ORY45628.1 - 0.02 14.1 0.1 0.032 13.4 0.1 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate hydrolase-like G3P_antiterm PF04309.12 ORY45628.1 - 0.025 14.0 0.2 0.066 12.6 0.1 1.7 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Dus PF01207.17 ORY45628.1 - 0.047 12.8 0.0 0.16 11.1 0.0 1.9 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) adh_short PF00106.25 ORY45630.1 - 2.6e-45 154.3 0.2 3.4e-45 153.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY45630.1 - 1.1e-25 90.6 0.3 1.3e-25 90.3 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY45630.1 - 1.6e-07 31.5 2.0 4.7e-07 29.9 2.0 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 ORY45630.1 - 0.053 12.6 0.0 0.84 8.7 0.1 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein AAA PF00004.29 ORY45631.1 - 7.1e-37 126.8 0.0 1.1e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY45631.1 - 4e-09 36.1 0.0 8.8e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 ORY45631.1 - 5.5e-06 26.9 0.2 0.00032 21.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 ORY45631.1 - 9.6e-06 25.6 0.2 0.0001 22.3 0.2 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 ORY45631.1 - 1.5e-05 24.7 0.6 0.028 14.0 0.5 2.4 1 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 ORY45631.1 - 6.2e-05 23.3 0.3 0.0016 18.7 0.2 2.7 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 ORY45631.1 - 6.6e-05 23.1 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 ORY45631.1 - 9.8e-05 22.2 0.0 0.00025 20.8 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 ORY45631.1 - 0.00017 21.6 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 ORY45631.1 - 0.00032 20.0 0.0 0.00051 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 ORY45631.1 - 0.00045 20.0 0.0 0.00067 19.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 ORY45631.1 - 0.00073 19.7 0.0 0.0016 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 ORY45631.1 - 0.00091 18.7 0.2 0.0018 17.7 0.2 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 ORY45631.1 - 0.00094 19.0 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 ORY45631.1 - 0.0014 19.1 0.0 0.0025 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ORY45631.1 - 0.0015 18.1 0.2 0.022 14.3 0.1 2.6 1 1 1 2 2 2 1 P-loop containing dynein motor region TniB PF05621.11 ORY45631.1 - 0.0035 16.8 0.1 2.9 7.3 0.0 3.0 1 1 1 3 3 3 1 Bacterial TniB protein RNA_helicase PF00910.22 ORY45631.1 - 0.0055 17.1 0.0 0.017 15.5 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_28 PF13521.6 ORY45631.1 - 0.0074 16.6 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 ORY45631.1 - 0.0089 15.4 0.0 0.12 11.7 0.0 2.2 1 1 0 2 2 2 1 KaiC TsaE PF02367.17 ORY45631.1 - 0.012 15.6 0.1 0.023 14.7 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 ORY45631.1 - 0.014 15.3 0.0 0.039 13.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Guanylate_kin PF00625.21 ORY45631.1 - 0.017 14.8 0.0 0.32 10.7 0.0 2.7 2 1 0 2 2 2 0 Guanylate kinase Sigma54_activ_2 PF14532.6 ORY45631.1 - 0.021 14.9 0.0 0.063 13.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 ORY45631.1 - 0.022 13.8 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 ORY45631.1 - 0.027 14.2 0.6 0.071 12.8 0.0 2.1 2 1 0 2 2 1 0 Sigma-54 interaction domain AAA_21 PF13304.6 ORY45631.1 - 0.029 14.2 0.2 2.9 7.6 0.1 2.4 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system TIP49 PF06068.13 ORY45631.1 - 0.032 13.5 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain CPT PF07931.12 ORY45631.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Bac_DnaA PF00308.18 ORY45631.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein PhoH PF02562.16 ORY45631.1 - 0.14 11.6 0.4 0.26 10.7 0.4 1.4 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 ORY45631.1 - 0.14 12.7 0.0 0.27 11.8 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_11 PF13086.6 ORY45631.1 - 0.17 11.7 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORY45631.1 - 0.19 11.0 0.2 0.32 10.2 0.2 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 ORY45631.1 - 0.28 10.9 0.5 0.59 9.8 0.2 1.6 2 0 0 2 2 2 0 AAA domain Methyltr_RsmB-F PF01189.17 ORY45632.1 - 1.4e-75 253.4 0.0 2.1e-75 252.8 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 ORY45632.1 - 2.3e-08 34.4 0.0 6e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 ORY45632.1 - 0.0014 18.5 0.0 0.0026 17.5 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein FtsJ PF01728.19 ORY45632.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 ORY45632.1 - 0.021 14.6 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF2431 PF10354.9 ORY45632.1 - 0.081 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) SLX9 PF15341.6 ORY45633.1 - 8e-13 48.9 2.3 9.3e-13 48.7 2.3 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 zf-CCCH_6 PF18585.1 ORY45633.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 DUF1394 PF07159.12 ORY45634.1 - 1.1e-79 267.9 0.0 1.4e-79 267.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) WASH-7_N PF14745.6 ORY45634.1 - 0.019 13.5 0.0 0.028 13.0 0.0 1.2 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal NTP_transferase PF00483.23 ORY45635.1 - 4.4e-52 177.1 0.0 7.8e-52 176.3 0.0 1.3 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 ORY45635.1 - 1.2e-11 43.9 5.9 4.8e-10 38.7 2.5 2.9 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 ORY45635.1 - 5.5e-11 43.1 0.0 7.9e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 ORY45635.1 - 0.0001 22.0 1.1 0.0001 22.0 1.1 2.6 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 ORY45635.1 - 0.0069 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase Fucokinase PF07959.12 ORY45635.1 - 0.031 13.2 0.1 0.73 8.7 0.1 2.1 2 0 0 2 2 2 0 L-fucokinase IspD PF01128.19 ORY45635.1 - 0.069 12.9 0.1 0.2 11.4 0.0 1.7 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase VTC PF09359.10 ORY45636.1 - 6.1e-91 304.6 2.3 8.5e-91 304.2 2.3 1.2 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 ORY45636.1 - 2.4e-11 43.9 1.8 2.4e-11 43.9 1.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 ORY45636.1 - 0.00059 19.9 0.1 0.00059 19.9 0.1 2.3 3 0 0 3 3 3 1 SPX domain SLATT_5 PF18160.1 ORY45636.1 - 0.081 12.2 3.2 2 7.7 0.1 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Kelch_4 PF13418.6 ORY45637.1 - 0.69 10.0 3.7 1.3 9.1 0.1 3.1 4 0 0 4 4 4 0 Galactose oxidase, central domain DUF5418 PF17439.2 ORY45638.1 - 0.066 13.3 0.2 0.14 12.2 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5418) E1-E2_ATPase PF00122.20 ORY45640.1 - 8.2e-28 97.1 0.7 8.2e-28 97.1 0.7 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORY45640.1 - 2.6e-14 54.0 0.1 6e-08 33.2 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY45640.1 - 0.00014 21.5 0.1 0.0006 19.4 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 ORY45640.1 - 0.0032 17.5 0.0 0.0092 16.0 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) S6PP PF05116.13 ORY45640.1 - 0.014 15.0 0.0 0.051 13.1 0.0 1.8 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 ORY45640.1 - 0.031 14.0 0.1 0.26 11.0 0.1 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase SH3_9 PF14604.6 ORY45641.1 - 2.1e-06 27.5 0.3 3.6e-06 26.7 0.3 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY45641.1 - 0.00037 20.0 0.2 0.00097 18.7 0.0 1.7 2 0 0 2 2 2 1 SH3 domain PI3K_1B_p101 PF10486.9 ORY45641.1 - 1.3 6.7 3.9 2.1 6.0 3.9 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit IBR PF01485.21 ORY45642.1 - 2.2e-18 66.2 30.0 3.7e-12 46.3 7.0 3.6 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 ORY45642.1 - 9.6e-08 32.2 6.3 9.6e-08 32.2 6.3 4.2 4 2 0 4 4 3 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY45642.1 - 3.8e-06 26.8 2.7 3.8e-06 26.8 2.7 2.7 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY45642.1 - 4e-05 23.4 5.4 4e-05 23.4 5.4 4.4 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY45642.1 - 0.00089 19.2 3.9 0.00089 19.2 3.9 4.2 2 1 2 4 4 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY45642.1 - 0.0035 17.2 5.5 0.0035 17.2 5.5 4.5 5 1 1 6 6 5 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 ORY45642.1 - 0.0089 15.8 7.9 0.0089 15.8 7.9 4.8 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY45642.1 - 0.042 14.0 1.9 0.042 14.0 1.9 4.5 4 1 1 5 5 5 0 zinc finger of C3HC4-type, RING NupH_GANP PF16768.5 ORY45642.1 - 0.072 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin homology of Germinal-centre associated nuclear protein HHH_8 PF14716.6 ORY45642.1 - 0.18 12.2 0.2 0.35 11.3 0.2 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain zf-RING_11 PF17123.5 ORY45642.1 - 0.23 11.2 6.3 0.12 12.2 3.3 2.2 2 0 0 2 2 2 0 RING-like zinc finger 3-HAO PF06052.12 ORY45643.1 - 2.9e-64 215.3 0.0 3.3e-64 215.1 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 ORY45643.1 - 1.8e-05 24.4 0.0 2.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Cupin domain ARD PF03079.14 ORY45643.1 - 0.015 15.4 0.1 0.029 14.6 0.0 1.5 2 0 0 2 2 2 0 ARD/ARD' family DZR PF12773.7 ORY45643.1 - 0.036 14.1 1.5 0.036 14.1 1.5 1.6 2 0 0 2 2 2 0 Double zinc ribbon AraC_binding PF02311.19 ORY45643.1 - 0.047 13.6 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain zf-C2H2 PF00096.26 ORY45644.1 - 5.7e-06 26.5 5.6 0.041 14.4 1.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY45644.1 - 0.00021 21.6 1.8 0.00021 21.6 1.8 1.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY45644.1 - 0.016 16.0 3.5 0.59 11.1 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY45644.1 - 0.019 15.3 0.5 0.36 11.1 0.1 2.5 2 1 0 2 2 2 0 C2H2-type zinc ribbon zf-C2H2 PF00096.26 ORY45645.1 - 1.2e-05 25.5 11.1 0.007 16.8 1.3 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY45645.1 - 0.00025 21.3 4.7 0.00025 21.3 4.7 2.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY45645.1 - 0.0024 18.6 8.2 0.1 13.5 0.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY45645.1 - 0.029 14.6 2.0 0.085 13.2 2.0 1.8 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 ORY45645.1 - 0.042 14.0 0.1 0.16 12.1 0.1 1.8 1 1 1 2 2 2 0 Aberrant zinc-finger BCD PF15461.6 ORY45646.1 - 5.7e-42 144.1 11.3 5.2e-38 131.1 9.3 2.3 2 0 0 2 2 2 2 Beta-carotene 15,15'-dioxygenase OPT PF03169.15 ORY45647.1 - 2.9e-59 201.3 29.4 5.2e-34 117.9 16.6 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein OPT PF03169.15 ORY45648.1 - 2.2e-50 172.0 16.6 2.6e-50 171.7 16.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2109 PF09882.9 ORY45648.1 - 0.058 13.4 1.3 0.2 11.7 1.3 2.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2109) CPP1-like PF11833.8 ORY45648.1 - 0.16 11.6 0.4 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like zf-C2H2 PF00096.26 ORY45649.1 - 1.3e-10 41.1 13.1 1.5e-06 28.4 0.3 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY45649.1 - 2.7e-07 30.9 8.8 0.0012 19.5 0.2 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY45649.1 - 0.00016 21.6 6.6 0.017 15.1 0.5 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORY45649.1 - 0.00022 20.9 2.4 0.23 11.3 0.1 2.4 2 0 0 2 2 2 2 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 ORY45649.1 - 0.00023 21.4 7.8 0.011 16.1 1.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2HC_2 PF13913.6 ORY45649.1 - 0.0026 17.6 1.9 0.0052 16.7 1.9 1.6 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2HE PF16278.5 ORY45649.1 - 0.0063 16.9 1.1 0.98 9.9 1.0 2.5 1 1 1 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-LYAR PF08790.11 ORY45649.1 - 0.032 14.1 0.9 2.5 8.1 0.0 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-met PF12874.7 ORY45649.1 - 0.053 13.9 2.5 0.52 10.8 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 ORY45649.1 - 0.06 13.0 2.2 1.6 8.4 0.2 2.7 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain YhfH PF14149.6 ORY45649.1 - 0.11 12.5 0.1 16 5.6 0.0 2.3 2 0 0 2 2 2 0 YhfH-like protein Zn-ribbon_8 PF09723.10 ORY45649.1 - 0.14 12.3 2.7 0.82 9.8 1.8 2.2 1 1 1 2 2 2 0 Zinc ribbon domain zf-BED PF02892.15 ORY45649.1 - 0.33 11.0 6.0 0.31 11.1 2.2 2.6 1 1 1 2 2 2 0 BED zinc finger ABC_tran PF00005.27 ORY45650.1 - 1.5e-21 77.3 0.3 7.7e-10 39.4 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 ORY45650.1 - 1.1e-08 35.0 1.3 3.1e-08 33.6 1.3 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY45650.1 - 8.1e-07 29.1 0.0 0.0027 17.6 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 ORY45650.1 - 0.00086 19.6 0.0 0.0031 17.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF87 PF01935.17 ORY45650.1 - 0.001 19.2 1.1 0.0037 17.4 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 ORY45650.1 - 0.01 15.8 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 ORY45650.1 - 0.015 15.0 0.1 0.054 13.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 ORY45650.1 - 0.015 14.7 0.6 0.033 13.5 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 ORY45650.1 - 0.03 13.3 0.2 0.03 13.3 0.2 2.8 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Hamartin PF04388.12 ORY45650.1 - 0.041 12.6 3.5 0.061 12.0 3.5 1.2 1 0 0 1 1 1 0 Hamartin protein DUF815 PF05673.13 ORY45650.1 - 0.071 12.3 0.0 0.24 10.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 ORY45650.1 - 0.08 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.23 ORY45650.1 - 0.08 13.0 0.0 0.31 11.1 0.0 2.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 ORY45650.1 - 0.13 12.2 0.4 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_15 PF13175.6 ORY45650.1 - 0.3 10.8 2.1 1.3 8.7 0.0 2.7 2 1 1 3 3 3 0 AAA ATPase domain Ndc1_Nup PF09531.10 ORY45650.1 - 2.5 6.7 7.6 4.5 5.8 7.6 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ORC6 PF05460.13 ORY45650.1 - 4.6 6.4 11.2 8.7 5.5 11.2 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RAP1 PF07218.11 ORY45650.1 - 8.7 4.5 10.0 14 3.8 10.0 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pol_alpha_B_N PF08418.10 ORY45650.1 - 8.7 6.2 12.4 2.9 7.8 8.3 2.1 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal TFIIA PF03153.13 ORY45651.1 - 0.0066 16.5 4.3 0.0075 16.3 4.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit NIF PF03031.18 ORY45652.1 - 9.5e-48 161.9 0.2 1.5e-47 161.3 0.2 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase AA_permease_2 PF13520.6 ORY45652.1 - 1.5e-27 96.5 57.8 5.2e-24 84.8 32.3 2.8 3 0 0 3 3 3 2 Amino acid permease AA_permease PF00324.21 ORY45652.1 - 1.6e-10 40.2 31.7 1.6e-10 40.2 31.7 2.4 3 0 0 3 3 3 1 Amino acid permease WD40 PF00400.32 ORY45654.1 - 6.9e-48 159.6 24.0 3e-09 37.3 0.1 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY45654.1 - 4.5e-15 55.7 6.5 0.0032 17.7 0.0 6.6 2 1 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY45654.1 - 2.4e-09 36.6 1.5 0.062 12.2 0.0 5.9 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ORY45654.1 - 1.4e-05 24.6 0.1 0.38 10.0 0.0 3.6 2 2 1 3 3 3 2 WD40-like domain Nup160 PF11715.8 ORY45654.1 - 0.0052 15.5 9.5 2 6.9 0.0 5.0 2 1 3 6 6 6 2 Nucleoporin Nup120/160 PD40 PF07676.12 ORY45654.1 - 0.018 15.0 0.3 19 5.3 0.0 4.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat VID27 PF08553.10 ORY45654.1 - 0.039 13.0 0.1 2.5 7.1 0.0 2.3 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain SGL PF08450.12 ORY45654.1 - 0.048 13.2 0.2 0.1 12.2 0.2 1.5 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region LRR_6 PF13516.6 ORY45656.1 - 2.6e-10 39.5 18.7 0.23 11.6 0.2 10.5 12 0 0 12 12 12 5 Leucine Rich repeat LRR_4 PF12799.7 ORY45656.1 - 4.6e-05 23.7 24.9 5.1 7.6 0.2 8.4 5 4 2 8 8 8 4 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORY45656.1 - 0.017 15.0 1.1 0.055 13.4 1.1 1.9 1 0 0 1 1 1 0 F-box-like LRR_1 PF00560.33 ORY45656.1 - 2.8 8.8 17.0 1.1e+02 4.0 0.0 8.1 6 3 1 7 7 7 0 Leucine Rich Repeat AA_permease_2 PF13520.6 ORY45657.1 - 2.4e-41 142.0 38.7 2.4e-41 142.0 38.7 1.7 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 ORY45657.1 - 1e-15 57.3 38.5 1.5e-15 56.8 38.5 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY45658.1 - 5.3e-43 147.4 44.2 5.3e-43 147.4 44.2 1.6 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 ORY45658.1 - 1.2e-14 53.8 43.0 2.6e-14 52.7 42.8 1.7 1 1 0 1 1 1 1 Amino acid permease OPT PF03169.15 ORY45659.1 - 5.3e-95 319.3 56.3 8.5e-93 312.0 56.3 2.1 1 1 0 1 1 1 1 OPT oligopeptide transporter protein Sulfate_transp PF00916.20 ORY45660.1 - 3.2e-84 282.9 18.2 2.1e-50 171.6 5.9 2.1 1 1 1 2 2 2 2 Sulfate permease family STAS PF01740.21 ORY45660.1 - 1.5e-14 53.6 0.0 3.2e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 ORY45660.1 - 0.0053 17.1 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ORY45660.1 - 0.85 10.0 12.0 0.038 14.4 5.0 2.3 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily CoatB PF10389.9 ORY45660.1 - 1.1 9.2 4.6 0.99 9.3 0.8 3.0 2 0 0 2 2 2 0 Bacteriophage coat protein B HA2 PF04408.23 ORY45661.1 - 9.5e-19 67.7 0.5 9.5e-19 67.7 0.5 2.6 2 1 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ORY45661.1 - 1.1e-11 45.0 0.0 2.4e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 ORY45661.1 - 0.019 15.3 0.0 0.062 13.7 0.0 1.8 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold PGI PF00342.19 ORY45662.1 - 3.8e-242 804.1 1.2 5e-242 803.7 0.2 1.6 2 0 0 2 2 2 1 Phosphoglucose isomerase Urease_beta PF00699.20 ORY45662.1 - 0.025 14.6 0.0 0.07 13.2 0.0 1.7 1 0 0 1 1 1 0 Urease beta subunit DUF4148 PF13663.6 ORY45662.1 - 0.063 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) WD40 PF00400.32 ORY45663.1 - 2.7e-08 34.3 14.7 0.0004 21.1 0.2 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ_3 PF13570.6 ORY45663.1 - 0.03 14.8 0.4 17 6.1 0.1 3.8 3 0 0 3 3 3 0 PQQ-like domain DUF3405 PF11885.8 ORY45665.1 - 3.8e-20 72.0 0.4 3.4e-17 62.3 0.6 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3405) zf-Nse PF11789.8 ORY45665.1 - 0.066 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF3405 PF11885.8 ORY45666.1 - 1.8e-23 83.0 0.9 4.1e-18 65.3 0.9 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3405) zf-C2H2 PF00096.26 ORY45667.1 - 4e-07 30.1 9.8 0.00018 21.8 3.2 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY45667.1 - 0.001 19.7 8.7 0.0051 17.5 2.7 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-LYAR PF08790.11 ORY45667.1 - 0.02 14.8 0.4 0.051 13.5 0.4 1.7 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.5 ORY45667.1 - 0.021 14.6 3.0 0.043 13.6 3.0 1.4 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 ORY45667.1 - 0.1 13.1 2.6 9.3 6.9 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf_CopZ PF18423.1 ORY45667.1 - 0.12 12.4 0.5 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 Zinc binding domain Tim44 PF04280.15 ORY45668.1 - 1e-24 87.3 0.0 2.7e-24 86.0 0.0 1.8 1 0 0 1 1 1 1 Tim44-like domain Gluconate_2-dh3 PF13618.6 ORY45668.1 - 0.064 13.5 0.9 0.25 11.6 1.0 2.0 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 Stomoxyn PF11585.8 ORY45668.1 - 1.6 8.8 8.0 0.22 11.6 1.7 2.6 2 0 0 2 2 2 0 Insect antimicrobial peptide, stomoxyn DUF4865 PF16157.5 ORY45668.1 - 6.8 6.6 6.7 13 5.7 3.2 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4865) Cyclin PF08613.11 ORY45675.1 - 5.5e-07 30.1 0.1 5.5e-07 30.1 0.1 2.3 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 ORY45675.1 - 0.001 18.8 0.1 0.002 17.9 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Zn_clus PF00172.18 ORY45676.1 - 0.002 18.2 10.9 0.0042 17.2 10.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 ORY45677.1 - 0.00027 21.2 13.0 0.0097 16.3 1.9 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY45677.1 - 0.63 11.0 10.3 3.6 8.7 3.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger PAF-AH_p_II PF03403.13 ORY45678.1 - 1.1e-34 119.5 0.1 4.4e-17 61.7 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Hydrolase_4 PF12146.8 ORY45678.1 - 8.5e-06 25.2 0.7 0.011 15.0 0.6 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 ORY45678.1 - 3.4e-05 22.9 0.0 9.1e-05 21.5 0.0 1.7 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.7 ORY45678.1 - 0.00018 22.2 0.1 0.00024 21.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family OTU PF02338.19 ORY45679.1 - 2.8e-14 53.7 0.0 5.5e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 ORY45679.1 - 1.6e-09 37.6 0.1 1.1e-05 25.1 0.0 2.2 1 1 1 2 2 2 2 Peptidase C65 Otubain NETI PF14044.6 ORY45679.1 - 0.051 13.3 1.5 0.068 12.9 0.0 2.0 2 0 0 2 2 2 0 NETI protein DUF1672 PF07901.11 ORY45679.1 - 0.081 12.2 0.1 0.081 12.2 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1672) PGM_PMM_I PF02878.16 ORY45680.1 - 7.3e-30 103.5 0.1 1.2e-29 102.8 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 ORY45680.1 - 1.2e-26 93.1 0.0 2.1e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 ORY45680.1 - 5.1e-14 52.7 0.0 1.9e-13 50.9 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 ORY45680.1 - 2.3e-05 24.5 0.0 5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain LRR_8 PF13855.6 ORY45681.1 - 8.7e-16 57.4 29.1 2e-07 30.7 5.1 3.2 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY45681.1 - 3.3e-12 46.4 13.2 5.4e-05 23.5 0.3 3.6 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY45681.1 - 1.2e-06 28.2 15.4 0.52 11.0 1.0 5.4 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.6 ORY45681.1 - 3e-05 23.7 6.6 2.8 8.2 0.0 5.2 5 0 0 5 5 5 3 Leucine Rich repeat LRR_9 PF14580.6 ORY45681.1 - 0.0032 17.0 0.4 1.5 8.3 0.1 2.1 1 1 1 2 2 2 2 Leucine-rich repeat DUF676 PF05057.14 ORY45682.1 - 2.5e-35 122.0 0.0 3.4e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 ORY45682.1 - 0.0063 16.4 0.0 0.012 15.4 0.0 1.5 1 1 0 1 1 1 1 Palmitoyl protein thioesterase Trimer_CC PF08954.11 ORY45682.1 - 0.12 11.9 0.3 0.73 9.4 0.4 2.1 2 0 0 2 2 2 0 Trimerisation motif Abhydrolase_6 PF12697.7 ORY45682.1 - 0.22 12.1 1.4 0.47 11.0 1.2 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family F-box-like PF12937.7 ORY45683.1 - 3e-06 27.0 0.6 3e-06 27.0 0.6 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY45683.1 - 1.7e-05 24.5 1.6 6.6e-05 22.7 0.1 2.5 2 0 0 2 2 2 1 F-box domain WD40 PF00400.32 ORY45683.1 - 0.0091 16.8 1.8 4 8.5 0.1 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat TB2_DP1_HVA22 PF03134.19 ORY45684.1 - 5.2e-05 23.1 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Hydrolase_3 PF08282.12 ORY45685.1 - 3.1e-53 181.1 0.0 3.7e-53 180.9 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 ORY45685.1 - 2.2e-14 53.6 0.0 1.7e-06 27.8 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 ORY45685.1 - 1e-05 25.9 0.0 0.038 14.3 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY45685.1 - 0.019 15.4 0.4 2.6 8.4 0.0 3.1 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase DUF4279 PF14106.6 ORY45685.1 - 0.16 12.2 0.0 0.31 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) Amidinotransf PF02274.17 ORY45686.1 - 3.9e-15 55.8 0.1 4.8e-15 55.5 0.1 1.1 1 0 0 1 1 1 1 Amidinotransferase zf-C2H2_4 PF13894.6 ORY45687.1 - 2.9e-08 33.9 4.4 0.0028 18.4 0.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY45687.1 - 5.7e-08 32.8 10.2 5.5e-05 23.4 0.8 2.9 3 0 0 3 3 2 2 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 ORY45687.1 - 0.00015 21.6 3.9 0.00018 21.3 0.7 2.5 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-BED PF02892.15 ORY45687.1 - 0.00015 21.7 3.1 0.54 10.3 0.2 3.7 4 0 0 4 4 4 2 BED zinc finger zf-C2H2_11 PF16622.5 ORY45687.1 - 0.0038 16.9 0.4 0.0038 16.9 0.4 2.8 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 ORY45687.1 - 0.019 15.0 2.1 0.99 9.5 0.1 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 ORY45687.1 - 0.035 14.8 0.1 0.064 13.9 0.1 1.5 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 ORY45687.1 - 0.036 14.5 0.8 5.5 7.5 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 ORY45687.1 - 0.13 12.7 0.3 0.13 12.7 0.3 3.0 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY45687.1 - 0.13 12.5 0.1 27 5.2 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ORY45687.1 - 0.23 11.8 1.0 13 6.2 0.0 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) OPT PF03169.15 ORY45688.1 - 2.6e-14 52.8 11.5 3e-14 52.6 11.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein EB PF01683.18 ORY45690.1 - 0.019 15.3 1.4 0.019 15.3 1.4 2.1 2 1 0 2 2 2 0 EB module UFD1 PF03152.14 ORY45691.1 - 2.4e-38 131.3 0.0 8.1e-24 84.0 0.0 2.8 2 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 Kdo PF06293.14 ORY45693.1 - 3e-05 23.5 0.0 3.7e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 ORY45693.1 - 0.00023 20.6 0.0 0.00033 20.1 0.0 1.2 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 ORY45693.1 - 0.029 14.3 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family PPR_2 PF13041.6 ORY45694.1 - 0.00017 21.7 0.0 0.17 12.1 0.0 3.8 3 0 0 3 3 3 2 PPR repeat family PPR_3 PF13812.6 ORY45694.1 - 0.0005 20.1 0.0 0.032 14.3 0.0 2.9 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PWI PF01480.17 ORY45695.1 - 6.8e-11 42.3 0.1 4.2e-10 39.8 0.0 2.3 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.22 ORY45695.1 - 0.00061 19.6 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arrestin_N PF00339.29 ORY45696.1 - 0.033 14.3 0.1 0.071 13.2 0.0 1.6 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain DUF1236 PF06823.12 ORY45696.1 - 0.21 11.5 1.9 0.68 9.9 1.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1236) Phage_holin_7_1 PF16081.5 ORY45697.1 - 0.098 12.8 2.0 0.26 11.5 2.0 1.7 1 0 0 1 1 1 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Ank PF00023.30 ORY45699.1 - 2.3e-08 34.1 0.2 7.7e-07 29.3 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 ORY45699.1 - 6.4e-08 32.7 0.0 1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY45699.1 - 4.6e-07 30.3 0.1 1.2e-06 29.0 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY45699.1 - 7.3e-07 29.0 0.2 1.7e-05 24.8 0.0 2.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 ORY45699.1 - 2.1e-06 28.1 0.0 1.2e-05 25.7 0.0 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) DUF962 PF06127.11 ORY45700.1 - 1.4e-16 60.3 0.1 1.8e-16 60.0 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Tecti-min-caps PF09300.10 ORY45700.1 - 0.051 13.6 0.1 0.091 12.8 0.1 1.5 1 1 0 1 1 1 0 Tectiviridae, minor capsid EB PF01683.18 ORY45701.1 - 0.03 14.6 1.5 0.03 14.6 1.5 2.3 3 0 0 3 3 3 0 EB module Gly_transf_sug PF04488.15 ORY45702.1 - 1.4e-06 28.8 0.0 2.6e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 ORY45702.1 - 0.029 13.8 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Kelch_3 PF13415.6 ORY45703.1 - 1.4e-19 69.8 12.4 6.1e-05 23.2 0.1 5.3 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 ORY45703.1 - 1.5e-17 63.1 1.2 0.0002 21.3 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 ORY45703.1 - 1.7e-17 63.0 1.0 9.4e-05 22.6 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 ORY45703.1 - 5.9e-17 61.4 14.3 3.5e-06 26.9 0.0 5.1 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_1 PF01344.25 ORY45703.1 - 8.7e-11 41.2 1.6 0.0051 16.4 0.1 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 ORY45703.1 - 2.4e-09 36.8 4.9 0.048 13.7 0.0 4.6 4 1 0 4 4 4 3 Kelch motif SPT6_acidic PF14632.6 ORY45704.1 - 0.00061 20.3 4.7 0.00078 20.0 4.7 1.1 1 0 0 1 1 1 1 Acidic N-terminal SPT6 DUF2992 PF11208.8 ORY45704.1 - 0.00093 19.5 4.2 0.0012 19.1 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2992) Spt5_N PF11942.8 ORY45704.1 - 0.014 16.3 7.5 0.021 15.8 7.5 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal XAP5 PF04921.14 ORY45704.1 - 0.047 13.5 7.1 0.054 13.3 7.1 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Apt1 PF10351.9 ORY45704.1 - 0.056 12.3 9.1 0.062 12.1 9.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Codanin-1_C PF15296.6 ORY45704.1 - 0.082 13.0 9.3 0.12 12.5 9.3 1.2 1 0 0 1 1 1 0 Codanin-1 C-terminus TFIIF_alpha PF05793.12 ORY45704.1 - 0.083 11.5 8.3 0.1 11.2 8.3 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 ORY45704.1 - 0.12 10.6 8.1 0.14 10.4 8.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Paramyxo_ncap PF00973.19 ORY45704.1 - 0.14 11.0 6.8 0.16 10.9 6.8 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Roughex PF06020.11 ORY45704.1 - 0.26 10.3 10.5 0.33 10.0 10.5 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Zip PF02535.22 ORY45704.1 - 0.81 8.8 3.3 0.87 8.7 3.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 ORY45704.1 - 1 8.1 9.5 1.1 8.0 9.5 1.0 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 ORY45704.1 - 2.5 7.7 17.7 3.1 7.4 17.7 1.1 1 0 0 1 1 1 0 Spt20 family SPOC PF07744.13 ORY45706.1 - 4.8e-12 46.0 0.0 8.5e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 ORY45706.1 - 8.5e-07 29.4 0.1 1.6e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain DNA_pol3_gamma3 PF12169.8 ORY45706.1 - 0.23 11.4 1.6 1 9.3 0.1 2.1 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III DUF1631 PF07793.11 ORY45706.1 - 9.2 4.6 12.3 16 3.8 12.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Phosphoesterase PF04185.14 ORY45707.1 - 9.3e-76 255.3 0.9 1.2e-75 255.0 0.9 1.1 1 0 0 1 1 1 1 Phosphoesterase family Sulfate_transp PF00916.20 ORY45708.1 - 5e-97 325.0 25.7 6.8e-97 324.6 25.7 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORY45708.1 - 2.7e-11 43.1 0.0 5.7e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 ORY45708.1 - 0.034 14.5 0.1 0.074 13.4 0.1 1.5 1 0 0 1 1 1 0 STAS domain EB1 PF03271.17 ORY45709.1 - 7.7e-12 45.3 0.1 1.6e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 ORY45709.1 - 0.0013 18.9 0.1 0.0025 18.0 0.1 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain Suppressor_APC PF11414.8 ORY45709.1 - 0.054 13.6 0.2 0.1 12.7 0.2 1.4 1 0 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein ubiquitin PF00240.23 ORY45710.1 - 0.0043 16.8 0.1 0.0066 16.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_4 PF18036.1 ORY45710.1 - 0.087 12.9 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain zf-4CXXC_R1 PF10497.9 ORY45710.1 - 0.17 12.1 10.0 0.28 11.4 10.0 1.3 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-C2H2_4 PF13894.6 ORY45710.1 - 0.51 11.3 0.0 0.51 11.3 0.0 2.9 2 1 1 3 3 3 0 C2H2-type zinc finger zf-B_box PF00643.24 ORY45710.1 - 1.4 9.1 11.5 0.35 11.1 6.5 2.1 2 0 0 2 2 2 0 B-box zinc finger Zn_Tnp_IS91 PF14319.6 ORY45710.1 - 1.8 8.7 13.6 0.59 10.2 7.8 2.1 1 1 1 2 2 2 0 Transposase zinc-binding domain C1_1 PF00130.22 ORY45711.1 - 1.6e-12 47.1 8.7 2.6e-12 46.4 8.7 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 ORY45711.1 - 0.029 14.3 5.2 0.069 13.1 5.2 1.7 1 0 0 1 1 1 0 PHD-finger DUF3916 PF13079.6 ORY45711.1 - 0.046 13.6 0.2 0.073 12.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3916) DUF2318 PF10080.9 ORY45711.1 - 0.049 13.7 1.5 0.12 12.5 1.5 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) DUF1068 PF06364.12 ORY45711.1 - 0.16 11.8 11.6 0.028 14.3 3.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1068) Rnk_N PF14760.6 ORY45711.1 - 0.24 11.9 2.1 1.3 9.6 1.4 2.2 2 0 0 2 2 2 0 Rnk N-terminus zinc-ribbons_6 PF07191.12 ORY45711.1 - 0.57 10.2 6.0 11 6.1 1.9 2.5 2 0 0 2 2 2 0 zinc-ribbons zf-HIT PF04438.16 ORY45711.1 - 0.9 9.5 5.8 4.6 7.2 1.3 2.7 2 0 0 2 2 2 0 HIT zinc finger PRKG1_interact PF15898.5 ORY45711.1 - 1.5 9.8 10.0 0.76 10.7 3.2 2.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain PocR PF10114.9 ORY45711.1 - 2.3 8.0 5.4 1.1 9.0 2.7 1.8 2 0 0 2 2 2 0 Sensory domain found in PocR zf-RING_9 PF13901.6 ORY45711.1 - 6.3 6.7 11.0 0.74 9.8 4.7 2.4 2 1 0 2 2 2 0 Putative zinc-RING and/or ribbon MFS_1 PF07690.16 ORY45712.1 - 1.8e-36 125.8 44.0 1.1e-35 123.3 44.0 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY45712.1 - 8.5e-12 44.3 18.0 1.1e-11 44.0 18.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY45712.1 - 1.7e-11 43.6 12.7 1.7e-11 43.6 12.7 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter JIP_LZII PF16471.5 ORY45713.1 - 0.0011 19.1 1.8 0.0011 19.1 1.8 2.1 2 0 0 2 2 2 1 JNK-interacting protein leucine zipper II APG6_N PF17675.1 ORY45713.1 - 0.022 15.3 8.7 0.032 14.8 8.7 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Pox_A_type_inc PF04508.12 ORY45713.1 - 0.026 14.4 0.8 0.18 11.7 0.0 2.8 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat bZIP_1 PF00170.21 ORY45713.1 - 0.031 14.4 0.7 0.031 14.4 0.7 2.3 2 0 0 2 2 2 0 bZIP transcription factor Csm1_N PF18504.1 ORY45713.1 - 0.053 13.9 8.3 0.25 11.7 2.0 2.4 1 1 1 2 2 2 0 Csm1 N-terminal domain DASH_Hsk3 PF08227.11 ORY45713.1 - 0.078 13.4 3.2 0.078 13.4 3.2 2.1 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like Cnn_1N PF07989.11 ORY45713.1 - 0.095 12.9 5.7 0.81 9.9 2.1 2.7 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 APC_N_CC PF16689.5 ORY45713.1 - 0.11 12.6 10.8 0.38 10.8 4.5 3.4 3 1 0 3 3 3 0 Coiled-coil N-terminus of APC, dimerisation domain PAXX PF15384.6 ORY45713.1 - 0.15 11.7 2.1 0.29 10.8 1.1 1.6 1 1 1 2 2 2 0 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 Tropomyosin_1 PF12718.7 ORY45713.1 - 0.16 12.1 10.2 0.36 11.0 9.8 1.8 1 1 1 2 2 2 0 Tropomyosin like Spc24 PF08286.11 ORY45713.1 - 0.39 11.0 8.0 1.2 9.4 7.3 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 ZapB PF06005.12 ORY45713.1 - 0.44 11.0 7.5 1.9 9.0 6.6 2.2 1 1 0 1 1 1 0 Cell division protein ZapB SlyX PF04102.12 ORY45713.1 - 0.68 10.6 3.9 1.7 9.3 1.2 2.5 1 1 1 2 2 2 0 SlyX bZIP_2 PF07716.15 ORY45713.1 - 1.1 9.4 4.4 0.67 10.1 0.7 2.4 2 1 1 3 3 3 0 Basic region leucine zipper LPP PF04728.13 ORY45713.1 - 1.2 9.6 5.3 0.55 10.7 1.6 2.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper LMBR1 PF04791.16 ORY45713.1 - 1.5 7.6 3.9 1.6 7.5 3.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CAP PF00188.26 ORY45714.1 - 1.8e-06 28.8 1.3 2.6e-06 28.3 1.3 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Cytochrom_C PF00034.21 ORY45714.1 - 0.056 14.6 0.3 0.13 13.4 0.3 1.6 1 0 0 1 1 1 0 Cytochrome c CAP PF00188.26 ORY45716.1 - 0.022 15.6 2.2 0.043 14.7 2.2 1.5 1 0 0 1 1 1 0 Cysteine-rich secretory protein family LysM PF01476.20 ORY45716.1 - 0.031 14.4 0.0 0.074 13.1 0.0 1.6 1 0 0 1 1 1 0 LysM domain VacA PF02691.15 ORY45716.1 - 0.17 9.7 1.7 0.23 9.3 1.7 1.1 1 0 0 1 1 1 0 Vacuolating cyotoxin LysM PF01476.20 ORY45717.1 - 2.1e-11 43.7 0.1 6.1e-06 26.2 0.0 3.7 3 0 0 3 3 3 3 LysM domain LysM PF01476.20 ORY45718.1 - 1.2e-10 41.2 0.0 0.0085 16.1 0.0 3.4 3 0 0 3 3 3 3 LysM domain LysM PF01476.20 ORY45720.1 - 2.9e-12 46.4 0.0 6.9e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 LysM domain LysM PF01476.20 ORY45721.1 - 0.025 14.6 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 LysM domain DEC-1_N PF04625.13 ORY45722.1 - 0.66 8.9 3.2 0.82 8.6 3.2 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region PRIMA1 PF16101.5 ORY45724.1 - 0.017 15.1 6.7 0.048 13.7 6.7 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Apt1 PF10351.9 ORY45724.1 - 0.022 13.6 1.9 0.026 13.4 1.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SOG2 PF10428.9 ORY45724.1 - 0.059 12.6 22.0 0.076 12.2 22.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CAP PF00188.26 ORY45724.1 - 0.14 13.0 6.7 0.061 14.2 2.5 2.5 2 1 0 2 2 2 0 Cysteine-rich secretory protein family SPX PF03105.19 ORY45724.1 - 6.8 6.5 10.1 8.5 6.2 10.1 1.1 1 0 0 1 1 1 0 SPX domain zf-C2H2 PF00096.26 ORY45725.1 - 0.00073 19.8 12.2 0.003 17.9 1.7 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_11 PF16622.5 ORY45725.1 - 0.00086 19.0 11.2 0.0044 16.8 2.0 2.7 2 0 0 2 2 2 2 zinc-finger C2H2-type zf_C2H2_ZHX PF18387.1 ORY45725.1 - 0.0089 15.6 1.9 0.31 10.7 0.7 2.6 1 1 1 2 2 2 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_3 PF13878.6 ORY45725.1 - 0.014 15.2 0.3 1.8 8.5 0.0 2.6 1 1 1 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-C2H2_4 PF13894.6 ORY45725.1 - 0.019 15.8 17.0 0.048 14.5 1.4 3.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 ORY45725.1 - 0.023 15.4 3.8 0.37 11.5 0.2 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 ORY45725.1 - 0.033 14.6 0.7 0.033 14.6 0.7 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY45725.1 - 0.074 13.1 1.2 0.074 13.1 1.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY45725.1 - 2.7 8.6 12.8 0.28 11.7 1.6 4.0 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY45725.1 - 3.7 8.0 12.3 1.5 9.2 6.2 2.8 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding OPT PF03169.15 ORY45726.1 - 5.9e-113 378.6 47.8 6.9e-113 378.4 47.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2109 PF09882.9 ORY45726.1 - 0.034 14.2 0.6 0.034 14.2 0.6 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2109) zf-C2H2 PF00096.26 ORY45727.1 - 1.4e-08 34.7 7.7 0.00032 21.0 1.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY45727.1 - 1.4e-06 28.6 10.1 0.00076 20.1 1.7 3.2 3 0 0 3 3 2 2 C2H2-type zinc finger zf-met PF12874.7 ORY45727.1 - 0.0042 17.4 1.7 0.46 10.9 0.1 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY45727.1 - 0.0068 16.4 0.2 0.0068 16.4 0.2 3.1 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 ORY45727.1 - 0.012 16.3 3.1 0.39 11.4 1.0 2.5 2 1 1 3 3 2 0 Zinc finger C2H2-type, 3 repeats Codanin-1_C PF15296.6 ORY45727.1 - 0.038 14.1 0.4 0.19 11.8 0.1 2.1 2 0 0 2 2 2 0 Codanin-1 C-terminus HypA PF01155.19 ORY45727.1 - 0.07 13.1 0.3 0.13 12.3 0.3 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf_C2H2_ZHX PF18387.1 ORY45727.1 - 0.11 12.2 2.6 0.41 10.3 0.5 2.4 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-BED PF02892.15 ORY45727.1 - 0.14 12.2 7.6 3.1 7.9 2.4 2.5 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_11 PF16622.5 ORY45727.1 - 0.16 11.8 5.3 7.4 6.4 1.7 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zinc_ribbon_4 PF13717.6 ORY45727.1 - 0.18 11.7 1.4 21 5.2 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain FOXP-CC PF16159.5 ORY45727.1 - 0.32 11.7 3.0 1.5 9.5 0.1 2.8 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 ORY45727.1 - 0.67 10.3 5.9 7.7 6.9 0.4 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 ORY45727.1 - 0.73 10.4 10.0 8.5 7.0 2.9 3.6 3 0 0 3 3 3 0 Zinc-finger double domain OPT PF03169.15 ORY45728.1 - 1.8e-90 304.4 34.4 8.6e-90 302.1 34.4 1.8 1 1 0 1 1 1 1 OPT oligopeptide transporter protein SET PF00856.28 ORY45729.1 - 3.2e-20 73.2 1.0 1.9e-19 70.7 1.0 1.9 1 1 0 1 1 1 1 SET domain AWS PF17907.1 ORY45729.1 - 1.6e-12 47.2 4.4 1.6e-12 47.2 4.4 2.5 3 0 0 3 3 3 1 AWS domain Gasdermin PF04598.12 ORY45730.1 - 0.19 11.2 0.2 0.25 10.7 0.2 1.1 1 0 0 1 1 1 0 Gasdermin pore forming domain LysM PF01476.20 ORY45731.1 - 1.2e-14 54.0 0.0 0.0003 20.8 0.0 4.0 4 0 0 4 4 4 3 LysM domain CAP PF00188.26 ORY45731.1 - 3e-09 37.8 0.0 2.1e-08 35.0 0.0 2.4 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Peptidase_M36 PF02128.15 ORY45732.1 - 6.3e-113 377.7 9.0 1.1e-112 376.8 9.0 1.4 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 ORY45732.1 - 1.1e-11 44.3 1.3 3.8e-11 42.6 1.3 2.0 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M50B PF13398.6 ORY45732.1 - 0.029 14.0 0.1 0.052 13.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Abhydrolase_1 PF00561.20 ORY45733.1 - 2.9e-12 46.8 0.1 4.5e-12 46.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold ChiC PF06483.11 ORY45733.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Chitinase C adh_short PF00106.25 ORY45734.1 - 3.1e-23 82.3 3.1 2.8e-12 46.5 0.3 3.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY45734.1 - 5.1e-13 49.1 0.7 1.8e-07 31.0 0.0 2.7 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 ORY45734.1 - 0.035 13.7 0.2 0.046 13.3 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family Epimerase PF01370.21 ORY45734.1 - 0.045 13.2 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MyTH4 PF00784.17 ORY45735.1 - 0.084 13.4 0.3 0.15 12.6 0.3 1.4 1 0 0 1 1 1 0 MyTH4 domain OPT PF03169.15 ORY45736.1 - 3.9e-121 405.6 49.9 4.6e-121 405.4 49.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ZYG-11_interact PF05884.12 ORY45736.1 - 0.033 13.6 1.8 0.67 9.3 0.0 2.6 2 0 0 2 2 2 0 Interactor of ZYG-11 Bestrophin PF01062.21 ORY45737.1 - 2.1e-33 116.0 0.6 3.2e-32 112.1 0.6 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF2374 PF09574.10 ORY45737.1 - 0.11 12.3 1.7 0.3 10.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) Radical_SAM PF04055.21 ORY45738.1 - 2.6e-09 37.7 0.0 4.9e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 ORY45738.1 - 1.9e-06 28.0 0.0 3.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 ORY45738.1 - 0.0014 18.9 0.0 0.0027 18.0 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain OPT PF03169.15 ORY45741.1 - 6.7e-113 378.4 59.0 8.9e-113 378.0 59.0 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.15 ORY45743.1 - 3.3e-75 254.0 40.4 5.4e-73 246.6 40.4 2.0 1 1 0 1 1 1 1 OPT oligopeptide transporter protein DUF4407 PF14362.6 ORY45743.1 - 0.21 10.9 3.4 0.55 9.5 3.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-RING_2 PF13639.6 ORY45744.1 - 8.1e-08 32.5 0.7 1.4e-07 31.7 0.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 ORY45744.1 - 7.6e-07 29.3 1.2 1.4e-06 28.5 1.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORY45744.1 - 8.1e-07 28.8 0.5 1.3e-06 28.2 0.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORY45744.1 - 1.7e-05 24.8 0.3 3.1e-05 23.9 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 ORY45744.1 - 2e-05 24.3 0.8 3.5e-05 23.6 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY45744.1 - 6.1e-05 23.0 2.2 0.0011 19.0 0.1 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 ORY45744.1 - 6.8e-05 22.9 0.3 0.00011 22.3 0.3 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 ORY45744.1 - 0.00061 19.7 0.4 0.00095 19.1 0.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY45744.1 - 0.00074 19.3 0.3 0.0011 18.8 0.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY45744.1 - 0.0017 18.2 0.3 0.0026 17.6 0.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 ORY45744.1 - 0.026 14.1 0.4 0.2 11.3 0.5 2.0 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 ORY45744.1 - 0.065 13.1 0.1 0.096 12.5 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 ORY45744.1 - 0.093 12.9 0.5 0.093 12.9 0.5 2.2 2 1 0 2 2 2 0 RING-variant domain zf-RING_11 PF17123.5 ORY45744.1 - 0.11 12.3 1.9 0.16 11.7 0.1 2.0 2 0 0 2 2 2 0 RING-like zinc finger RGS PF00615.19 ORY45746.1 - 4.6e-07 30.1 0.3 1.4e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain DUF3007 PF11460.8 ORY45747.1 - 0.00058 20.1 0.1 0.00091 19.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3007) Shisa PF13908.6 ORY45749.1 - 0.0044 17.3 2.3 0.0075 16.5 2.1 1.5 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF4448 PF14610.6 ORY45749.1 - 0.09 12.5 0.1 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) Rax2 PF12768.7 ORY45749.1 - 0.11 12.0 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF5349 PF17298.2 ORY45750.1 - 0.53 10.0 4.3 0.61 9.8 4.3 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5349) OPT PF03169.15 ORY45751.1 - 1.1e-121 407.4 52.1 1.3e-121 407.2 52.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein IBR PF01485.21 ORY45752.1 - 3.3e-10 40.0 7.2 3.3e-10 40.0 7.2 4.2 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 ORY45752.1 - 2.3e-06 27.8 27.7 0.00024 21.4 10.1 3.8 3 0 0 3 3 3 2 Ring finger domain zf-RING_UBOX PF13445.6 ORY45752.1 - 0.00016 21.6 7.1 0.00016 21.6 7.1 3.3 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY45752.1 - 0.00034 20.4 8.8 0.00034 20.4 8.8 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY45752.1 - 0.0018 18.1 5.3 0.0018 18.1 5.3 4.3 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) RWD PF05773.22 ORY45752.1 - 0.036 14.3 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 RWD domain zf-C3HC4_4 PF15227.6 ORY45752.1 - 4.8 7.4 30.3 1.1 9.5 8.9 4.1 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING 7TM_GPCR_Srd PF10317.9 ORY45753.1 - 0.0035 16.6 1.1 0.0064 15.7 1.1 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srd ABC_tran PF00005.27 ORY45756.1 - 1e-44 152.4 1.8 1.4e-28 100.1 0.1 4.3 3 1 1 4 4 4 3 ABC transporter SMC_N PF02463.19 ORY45756.1 - 8.4e-08 31.9 5.3 0.026 14.0 1.2 4.0 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORY45756.1 - 0.00023 21.5 0.3 0.043 14.1 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 ORY45756.1 - 0.00026 20.9 0.1 5.2 6.8 0.0 3.3 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 ORY45756.1 - 0.0027 17.8 0.1 0.08 13.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase MTABC_N PF16185.5 ORY45756.1 - 0.0075 15.8 7.8 0.027 14.0 7.8 2.0 1 0 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region RsgA_GTPase PF03193.16 ORY45756.1 - 0.011 15.7 0.3 6.6 6.6 0.0 2.5 2 0 0 2 2 2 0 RsgA GTPase ABC_membrane PF00664.23 ORY45756.1 - 0.013 15.2 1.3 0.013 15.2 1.3 5.4 4 1 1 5 5 5 0 ABC transporter transmembrane region AAA_29 PF13555.6 ORY45756.1 - 0.015 15.0 2.1 3 7.7 0.2 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_7 PF12775.7 ORY45756.1 - 0.018 14.6 0.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 ORY45756.1 - 0.037 14.4 0.0 6.2 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 ORY45756.1 - 0.12 12.4 0.6 1.8 8.6 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain TP_methylase PF00590.20 ORY45757.1 - 7.1e-26 91.5 0.7 8e-25 88.0 0.0 2.6 2 1 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 ORY45757.1 - 6.7e-07 29.7 0.0 1.3e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.6 ORY45757.1 - 8.6e-07 28.3 0.1 2e-06 27.1 0.1 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.6 ORY45757.1 - 0.00036 20.1 0.5 0.00075 19.1 0.2 1.7 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal CholecysA-Rec_N PF09193.10 ORY45759.1 - 0.0051 16.8 0.9 3.6 7.7 0.2 2.7 2 0 0 2 2 2 2 Cholecystokinin A receptor, N-terminal Pam17 PF08566.10 ORY45759.1 - 0.012 15.5 2.3 0.039 13.8 0.4 2.4 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 Pkinase_Tyr PF07714.17 ORY45761.1 - 0.0061 15.9 0.0 0.0078 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORY45761.1 - 0.08 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase PF00069.25 ORY45762.1 - 6.1e-37 127.4 0.0 7.7e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY45762.1 - 8.7e-22 77.6 0.0 1.1e-19 70.7 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY45762.1 - 0.0014 17.4 0.0 0.0018 17.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY45762.1 - 0.044 13.7 0.0 0.068 13.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY45762.1 - 0.046 13.0 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 ORY45762.1 - 0.066 12.6 0.1 0.095 12.0 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNase_H PF00075.24 ORY45854.1 - 1.5e-09 38.2 0.0 4.6e-09 36.6 0.0 1.9 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 ORY45854.1 - 0.0019 18.9 0.5 0.0019 18.9 0.5 2.3 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase SPATA1_C PF15743.5 ORY45855.1 - 0.0033 17.5 3.6 0.0051 16.9 3.6 1.2 1 0 0 1 1 1 1 Spermatogenesis-associated C-terminus DUF3015 PF11220.8 ORY45855.1 - 0.011 15.7 1.2 0.026 14.4 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) Exonuc_VII_L PF02601.15 ORY45855.1 - 0.062 12.9 3.7 0.094 12.3 3.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4355 PF14265.6 ORY45855.1 - 0.098 12.9 7.7 0.18 12.0 7.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) FlaC_arch PF05377.11 ORY45855.1 - 0.5 10.8 2.2 2.7 8.5 0.1 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 ORY45855.1 - 3.5 6.8 6.1 5.6 6.1 6.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF2203 PF09969.9 ORY45855.1 - 9.8 6.9 7.7 8.3 7.2 5.8 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DDE_3 PF13358.6 ORY45856.1 - 4.6e-20 71.9 0.0 5.5e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease E1-E2_ATPase PF00122.20 ORY45857.1 - 3e-28 98.6 1.4 7.9e-28 97.2 1.4 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 ORY45857.1 - 1.9e-17 64.3 1.0 3.8e-17 63.3 1.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY45857.1 - 1.4e-13 50.3 0.0 4.3e-13 48.7 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 ORY45857.1 - 0.00023 21.2 0.0 0.00069 19.7 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY45857.1 - 0.0037 17.0 0.2 0.012 15.4 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase AGTRAP PF06396.11 ORY45857.1 - 0.12 12.2 0.8 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 Angiotensin II, type I receptor-associated protein (AGTRAP) ComJ PF11033.8 ORY45857.1 - 0.17 11.6 0.1 0.41 10.4 0.1 1.6 1 0 0 1 1 1 0 Competence protein J (ComJ) adh_short PF00106.25 ORY45858.1 - 1.3e-17 63.9 0.0 4e-09 36.2 0.0 3.3 3 0 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 ORY45858.1 - 3e-12 46.6 0.0 1.4e-05 24.7 0.0 3.2 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.19 ORY45858.1 - 0.1 11.9 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SLC12 PF03522.15 ORY45858.1 - 1.4 7.9 3.8 2.1 7.3 3.8 1.2 1 0 0 1 1 1 0 Solute carrier family 12 SAPS PF04499.15 ORY45858.1 - 1.4 7.6 7.3 2.3 6.9 7.3 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Aldo_ket_red PF00248.21 ORY45861.1 - 3.1e-70 236.7 0.0 3.7e-70 236.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Det1 PF09737.9 ORY45862.1 - 1.6e-80 271.2 0.1 1.5e-51 175.8 0.0 2.2 2 0 0 2 2 2 2 De-etiolated protein 1 Det1 Read-through PF16814.5 ORY45862.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Read-through domain HPPK PF01288.20 ORY45862.1 - 0.12 12.8 0.0 0.52 10.8 0.0 2.0 1 1 0 1 1 1 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) HTH_21 PF13276.6 ORY45862.1 - 0.14 12.3 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 HTH-like domain BRE PF06113.12 ORY45863.1 - 1.9e-10 40.1 0.0 2.6e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) Glutaredoxin PF00462.24 ORY45864.1 - 3.3e-21 75.3 0.1 4.7e-21 74.8 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin DUF836 PF05768.14 ORY45864.1 - 0.0002 21.7 0.0 0.00025 21.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 ORY45864.1 - 0.0026 18.2 0.0 0.0033 17.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 ORY45864.1 - 0.047 14.1 0.3 0.11 13.0 0.3 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_3 PF13192.6 ORY45864.1 - 0.078 13.0 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain TraF PF13728.6 ORY45864.1 - 0.097 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein DSBA PF01323.20 ORY45864.1 - 0.1 12.3 0.2 0.15 11.8 0.2 1.5 1 1 0 1 1 1 0 DSBA-like thioredoxin domain GST_N_2 PF13409.6 ORY45864.1 - 0.19 12.1 0.0 0.24 11.7 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 ORY45865.1 - 5.4e-22 77.8 0.0 8e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 ORY45865.1 - 0.00027 21.3 0.0 0.00033 21.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 ORY45865.1 - 0.0006 20.2 0.1 0.0014 19.0 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain GST_N_2 PF13409.6 ORY45865.1 - 0.0015 18.8 0.0 0.0018 18.5 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF836 PF05768.14 ORY45865.1 - 0.0038 17.6 0.1 0.0052 17.2 0.1 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DUF953 PF06110.11 ORY45865.1 - 0.02 14.5 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_3 PF13192.6 ORY45865.1 - 0.052 13.6 0.0 0.1 12.7 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_9 PF14595.6 ORY45865.1 - 0.052 13.3 0.0 0.068 13.0 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin PF00085.20 ORY45865.1 - 0.084 12.9 0.1 0.098 12.6 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.10 ORY45865.1 - 0.087 12.5 0.2 0.14 11.8 0.2 1.4 1 1 0 1 1 1 0 Redoxin Mis12 PF05859.12 ORY45866.1 - 1.9e-24 86.2 0.3 2.9e-24 85.7 0.3 1.3 1 0 0 1 1 1 1 Mis12 protein SSP160 PF06933.11 ORY45866.1 - 0.033 12.4 14.3 0.046 11.9 14.3 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Med3 PF11593.8 ORY45866.1 - 0.042 13.1 6.8 0.053 12.7 6.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4618 PF15397.6 ORY45866.1 - 0.056 12.9 0.4 0.1 12.0 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DLIC PF05783.11 ORY45866.1 - 1 8.1 4.6 1.5 7.6 4.6 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Sporozoite_P67 PF05642.11 ORY45866.1 - 4.9 5.1 10.7 6.8 4.6 10.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pox_A_type_inc PF04508.12 ORY45866.1 - 5.2 7.1 6.2 6.9 6.7 1.7 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat FSA_C PF10479.9 ORY45866.1 - 8.2 4.4 14.3 11 4.0 14.3 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Acetyltransf_1 PF00583.25 ORY45867.1 - 6.2e-18 65.1 0.0 8.3e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY45867.1 - 1.6e-11 44.2 0.0 2.2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY45867.1 - 8e-11 42.2 0.1 1.1e-10 41.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY45867.1 - 2.2e-08 34.0 0.1 3.7e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 ORY45867.1 - 0.00097 18.8 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORY45867.1 - 0.0016 19.2 0.0 0.0017 19.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY45867.1 - 0.0073 16.4 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY45867.1 - 0.015 15.4 0.1 0.026 14.7 0.1 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase TMEM108 PF15759.5 ORY45868.1 - 0.021 13.9 6.4 0.028 13.4 6.4 1.1 1 0 0 1 1 1 0 TMEM108 family DUF1149 PF06619.11 ORY45869.1 - 0.024 14.9 0.2 7.8 6.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1149) DUF4659 PF15558.6 ORY45869.1 - 0.039 12.8 0.3 0.052 12.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4659) zf-MYND PF01753.18 ORY45870.1 - 1.4e-15 57.1 28.1 5.4e-08 32.8 11.0 2.7 2 0 0 2 2 2 2 MYND finger zf-C6H2 PF15801.5 ORY45870.1 - 0.00027 21.2 23.6 0.0016 18.7 2.5 3.4 3 1 0 3 3 3 2 zf-MYND-like zinc finger, mRNA-binding PAN_4 PF14295.6 ORY45871.1 - 0.00013 21.8 5.4 0.092 12.7 0.4 2.6 2 0 0 2 2 2 2 PAN domain PAN_3 PF08277.12 ORY45871.1 - 0.00087 19.1 0.8 0.00087 19.1 0.8 4.2 4 1 0 4 4 4 2 PAN-like domain LRR_8 PF13855.6 ORY45872.1 - 8.9e-18 63.8 6.4 1.2e-08 34.5 0.2 2.0 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY45872.1 - 3.3e-09 36.9 0.7 2.5e-05 24.5 0.3 2.3 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY45872.1 - 7.3e-06 25.8 0.2 1.6 9.6 0.0 3.6 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_6 PF13516.6 ORY45872.1 - 0.00011 21.9 1.7 0.57 10.4 0.0 3.4 3 0 0 3 3 3 2 Leucine Rich repeat zf-C2H2 PF00096.26 ORY45873.1 - 3.2e-09 36.7 29.0 0.00021 21.5 4.1 4.7 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY45873.1 - 4.4e-09 36.4 24.0 3.4e-06 27.2 0.2 5.4 5 1 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY45873.1 - 1.3e-06 28.7 29.4 0.0055 17.4 3.3 4.8 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY45873.1 - 0.00037 20.7 12.3 0.0013 19.0 3.1 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY45873.1 - 0.0023 18.3 9.7 0.0049 17.2 4.7 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 ORY45873.1 - 0.0041 16.9 5.7 0.41 10.4 0.1 3.2 3 0 0 3 3 3 2 C2H2-type zinc-finger domain CDH-cyt PF16010.5 ORY45873.1 - 0.0086 15.8 0.8 0.013 15.1 0.8 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase zf-C2H2_11 PF16622.5 ORY45873.1 - 0.091 12.5 0.2 0.091 12.5 0.2 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 ORY45873.1 - 0.88 9.6 10.3 3.7 7.7 1.7 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 ORY45873.1 - 4.2 8.1 12.6 56 4.5 2.7 3.8 2 1 1 3 3 3 0 FOXP coiled-coil domain Polysacc_deac_1 PF01522.21 ORY45874.1 - 9e-26 90.2 0.0 1.3e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF3530 PF12048.8 ORY45874.1 - 0.051 13.0 2.9 0.076 12.4 2.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3530) Ndc1_Nup PF09531.10 ORY45874.1 - 4.6 5.8 6.8 5.5 5.6 6.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Polysacc_deac_1 PF01522.21 ORY45875.1 - 3.6e-24 85.0 0.0 6.6e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase LRR_8 PF13855.6 ORY45876.1 - 1.8e-12 46.8 10.9 2.5e-08 33.6 2.7 2.1 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY45876.1 - 2.2e-09 37.5 1.6 8.7e-06 26.0 1.4 2.7 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY45876.1 - 1.2e-05 25.2 1.8 1.8 9.4 0.1 3.9 3 1 1 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 ORY45876.1 - 0.0022 17.9 3.1 0.16 12.1 0.3 3.1 3 0 0 3 3 3 2 Leucine Rich repeat PhoD PF09423.10 ORY45877.1 - 1.2e-05 24.6 0.7 0.0015 17.6 0.7 2.3 1 1 0 1 1 1 1 PhoD-like phosphatase GST_N PF02798.20 ORY45880.1 - 2.7e-15 56.5 0.3 6.9e-15 55.2 0.0 1.9 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY45880.1 - 1.1e-11 44.9 0.1 3e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY45880.1 - 1.3e-09 38.2 0.0 4.3e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY45880.1 - 2.6e-08 34.0 0.0 6.3e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY45880.1 - 1.3e-06 28.3 0.0 2.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY45880.1 - 6e-05 23.2 0.0 0.00013 22.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.16 ORY45882.1 - 3.7e-24 85.3 35.4 4e-24 85.2 24.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY45882.1 - 3.2e-07 29.6 7.0 3.2e-07 29.6 7.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 ORY45882.1 - 0.00047 18.7 7.4 0.063 11.7 0.3 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector TRI12 PF06609.13 ORY45882.1 - 0.0006 18.4 2.9 0.0006 18.4 2.9 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Stathmin PF00836.19 ORY45885.1 - 9.8e-05 22.3 2.7 0.0001 22.3 2.7 1.1 1 0 0 1 1 1 1 Stathmin family Peroxidase_2 PF01328.17 ORY45886.1 - 5.1e-53 180.4 0.0 6.2e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 PEMT PF04191.13 ORY45887.1 - 1e-36 125.5 10.6 1.7e-24 86.3 1.0 3.3 2 1 0 2 2 2 2 Phospholipid methyltransferase HECW_N PF16562.5 ORY45887.1 - 0.024 14.4 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 ORY45887.1 - 0.08 13.5 0.0 0.7 10.5 0.0 2.2 2 0 0 2 2 2 0 SKICH domain GST_N PF02798.20 ORY45888.1 - 1e-14 54.6 0.0 4.6e-14 52.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY45888.1 - 9.1e-10 38.8 0.0 1.6e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY45888.1 - 2.5e-09 37.3 0.0 6.1e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY45888.1 - 3e-08 33.8 0.0 7.2e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY45888.1 - 4.4e-07 30.0 0.0 9.7e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY45888.1 - 7.1e-05 22.7 0.1 0.00014 21.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain IBR PF01485.21 ORY45889.1 - 1.6e-12 47.4 26.3 6.9e-08 32.6 2.7 4.2 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain GST_N PF02798.20 ORY45890.1 - 1.8e-14 53.8 0.1 4.8e-14 52.5 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY45890.1 - 3.2e-11 43.3 0.0 6.7e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORY45890.1 - 6.5e-11 42.5 0.0 1.2e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY45890.1 - 2.1e-10 40.7 0.0 5.5e-10 39.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY45890.1 - 3.2e-08 33.7 0.0 7.1e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY45890.1 - 2.5e-07 30.6 0.0 4.4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CorA PF01544.18 ORY45891.1 - 7.3e-08 32.1 0.1 8.3e-08 31.9 0.1 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein CagA PF03507.13 ORY45891.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.4 1 1 0 1 1 1 0 CagA exotoxin TIR_2 PF13676.6 ORY45892.1 - 2.5e-14 53.9 0.1 1.7e-11 44.8 0.0 2.3 2 0 0 2 2 2 2 TIR domain TIR PF01582.20 ORY45892.1 - 7.2e-08 32.4 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 TIR domain BAR PF03114.18 ORY45892.1 - 0.13 11.9 0.1 13 5.3 0.1 2.2 1 1 1 2 2 2 0 BAR domain Spc7 PF08317.11 ORY45892.1 - 0.38 9.6 1.7 1.1 8.1 0.1 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Polyketide_cyc2 PF10604.9 ORY45893.1 - 8.5e-05 22.8 0.2 0.00049 20.4 0.2 1.9 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport RRN9 PF10680.9 ORY45893.1 - 0.57 10.5 0.1 0.57 10.5 0.1 2.1 1 1 1 2 2 2 0 RNA polymerase I specific transcription initiation factor WW PF00397.26 ORY45895.1 - 5.4e-13 48.8 1.4 1.5e-12 47.3 1.4 1.8 1 0 0 1 1 1 1 WW domain Beta-lactamase PF00144.24 ORY45895.1 - 0.037 13.3 5.0 0.05 12.8 5.0 1.1 1 0 0 1 1 1 0 Beta-lactamase DUF2076 PF09849.9 ORY45895.1 - 0.13 12.3 2.4 0.13 12.2 2.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pkinase PF00069.25 ORY45896.1 - 2.3e-62 210.8 0.0 4.2e-62 209.9 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY45896.1 - 1.6e-44 152.1 0.0 7.5e-44 150.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY45896.1 - 1.5e-07 30.5 0.3 5.8e-07 28.6 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 ORY45896.1 - 1.9e-05 24.2 0.5 3.9e-05 23.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORY45896.1 - 0.066 13.1 0.1 0.51 10.2 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 ORY45896.1 - 0.088 12.4 0.0 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 RIO1 family RE_EcoO109I PF14511.6 ORY45896.1 - 0.12 11.9 0.2 1 8.9 0.0 2.2 2 0 0 2 2 2 0 Type II restriction endonuclease EcoO109I Spore_II_R PF09551.10 ORY45896.1 - 1.1 9.8 3.7 2.1 8.8 3.7 1.4 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) Pyr_redox_2 PF07992.14 ORY45898.1 - 1.3e-36 126.3 0.5 1.8e-36 125.9 0.5 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY45898.1 - 2.8e-12 47.0 2.5 1.9e-10 41.1 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY45898.1 - 5.4e-06 25.8 0.1 1.4e-05 24.5 0.1 1.6 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ORY45898.1 - 0.00029 20.2 0.9 0.00036 19.9 0.1 1.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY45898.1 - 0.016 14.3 0.8 0.97 8.4 0.2 3.1 4 0 0 4 4 4 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 ORY45898.1 - 0.016 15.2 0.1 3.3 7.7 0.0 3.3 2 1 1 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 ORY45898.1 - 0.045 14.2 0.1 3.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.22 ORY45898.1 - 0.09 11.8 6.8 0.21 10.7 0.0 3.2 2 1 1 3 3 3 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 ORY45898.1 - 0.13 11.1 1.3 3 6.6 0.2 2.4 3 0 0 3 3 3 0 Tryptophan halogenase DAO PF01266.24 ORY45898.1 - 0.17 11.4 0.3 0.84 9.1 0.3 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase AhpC-TSA PF00578.21 ORY45899.1 - 2.5e-14 53.3 0.0 2.8e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY45899.1 - 2.9e-12 46.5 0.0 3.2e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 ORY45899.1 - 4.7e-05 23.6 0.0 7.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 ORY45899.1 - 0.0018 18.4 0.1 0.0044 17.2 0.1 1.6 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 ORY45899.1 - 0.0025 18.3 0.0 0.0033 17.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain SRAP PF02586.14 ORY45900.1 - 7.8e-32 110.6 0.0 1.1e-31 110.2 0.0 1.1 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) WW PF00397.26 ORY45902.1 - 7.9e-06 25.9 6.3 1e-05 25.5 6.3 1.2 1 0 0 1 1 1 1 WW domain Abhydrolase_3 PF07859.13 ORY45903.1 - 1.8e-45 155.4 0.0 2.6e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY45903.1 - 2.5e-15 56.2 0.0 3.7e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 ORY45903.1 - 3.7e-05 23.1 0.0 0.0015 17.8 0.0 2.5 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 ORY45903.1 - 0.021 14.7 0.0 0.072 12.9 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 ORY45903.1 - 0.062 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) RRF_GI PF12614.8 ORY45903.1 - 0.12 12.5 0.3 0.34 11.1 0.1 1.8 2 0 0 2 2 2 0 Ribosome recycling factor PhoD PF09423.10 ORY45905.1 - 0.00048 19.2 0.1 0.013 14.6 0.0 2.2 2 0 0 2 2 2 2 PhoD-like phosphatase WW PF00397.26 ORY45908.1 - 3.5e-10 39.8 0.2 6.3e-10 39.0 0.2 1.5 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 ORY45908.1 - 3.2e-08 34.0 8.3 4.6e-08 33.4 8.3 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) EspB PF05802.11 ORY45908.1 - 0.15 12.1 0.9 0.21 11.6 0.9 1.2 1 0 0 1 1 1 0 Enterobacterial EspB protein DUF3482 PF11981.8 ORY45908.1 - 7.8 5.8 10.1 5.7 6.2 8.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3482) TFIIA PF03153.13 ORY45908.1 - 9.8 6.1 14.0 12 5.7 14.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WW PF00397.26 ORY45909.1 - 1.8e-09 37.5 0.5 3.1e-09 36.8 0.5 1.4 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 ORY45909.1 - 0.0012 18.9 10.9 0.0014 18.7 10.9 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) TFIIA PF03153.13 ORY45909.1 - 3.7 7.4 11.8 3.8 7.4 11.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pinin_SDK_memA PF04696.13 ORY45910.1 - 2.5 8.2 46.6 2 8.5 26.4 2.5 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Homeodomain PF00046.29 ORY45911.1 - 6.8e-19 67.5 5.5 7.9e-19 67.3 5.5 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY45911.1 - 0.0025 17.7 0.7 0.0045 16.9 0.7 1.4 1 0 0 1 1 1 1 Homeobox KN domain KH_dom-like PF14714.6 ORY45911.1 - 0.069 13.5 0.2 0.082 13.2 0.2 1.1 1 0 0 1 1 1 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 7tm_3 PF00003.22 ORY45912.1 - 6.6e-25 88.2 24.5 1.2e-24 87.4 24.5 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR PBP_like_2 PF12849.7 ORY45912.1 - 1.7e-21 77.2 0.8 2.5e-21 76.6 0.8 1.1 1 0 0 1 1 1 1 PBP superfamily domain DUF1700 PF08006.11 ORY45912.1 - 0.06 12.9 8.2 0.19 11.2 8.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Herpes_LMP1 PF05297.11 ORY45912.1 - 8.3 5.5 7.7 15 4.6 7.7 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Glyco_hydro_9 PF00759.19 ORY45913.1 - 0.0093 15.4 3.4 0.015 14.7 3.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DUF410 PF04190.13 ORY45913.1 - 0.032 14.0 3.0 0.13 12.0 1.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF410) DUF5326 PF17260.2 ORY45913.1 - 0.55 10.4 6.4 0.39 10.9 1.6 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5326) DUF4231 PF14015.6 ORY45913.1 - 4.5 7.8 7.8 10 6.7 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) DUF2951 PF11166.8 ORY45913.1 - 7.5 6.8 8.7 4.3 7.6 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2951) DUF755 PF05501.11 ORY45913.1 - 9.7 6.5 9.1 0.54 10.5 0.1 3.2 5 0 0 5 5 5 0 Domain of unknown function (DUF755) cNMP_binding PF00027.29 ORY45915.1 - 7.8e-07 29.1 0.0 1.1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain cNMP_binding PF00027.29 ORY45917.1 - 5.1e-14 52.1 0.0 1.4e-07 31.5 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Mem_trans PF03547.18 ORY45918.1 - 1.7e-06 26.7 5.7 0.002 16.6 0.9 3.0 2 1 0 2 2 2 2 Membrane transport protein RFX5_DNA_bdg PF14621.6 ORY45918.1 - 0.14 11.9 2.4 0.22 11.3 2.4 1.2 1 0 0 1 1 1 0 RFX5 DNA-binding domain Sporozoite_P67 PF05642.11 ORY45919.1 - 0.21 9.6 2.6 0.32 9.0 2.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TFIIE-A_C PF11521.8 ORY45919.1 - 1.6 9.1 7.1 2.8 8.3 4.0 2.4 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha Ank_3 PF13606.6 ORY45921.1 - 1.1e-20 71.5 0.0 4.3e-05 23.6 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.7 ORY45921.1 - 1.6e-20 73.5 0.0 1.8e-13 50.8 0.0 3.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY45921.1 - 7.5e-20 70.7 0.1 0.00024 21.3 0.0 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY45921.1 - 8.1e-17 61.4 0.2 2.7e-06 27.8 0.0 4.4 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY45921.1 - 2.8e-14 52.8 0.0 8.2e-05 22.9 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat DUF4026 PF13218.6 ORY45922.1 - 0.0094 15.0 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4026) ASH PF15780.5 ORY45923.1 - 8.9e-05 22.6 0.1 0.0074 16.5 0.0 3.4 4 0 0 4 4 4 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 ORY45923.1 - 0.017 15.2 0.5 2.2 8.5 0.0 3.2 4 0 0 4 4 4 0 Flagellar-associated PapD-like Motile_Sperm PF00635.26 ORY45923.1 - 0.046 13.6 0.5 0.32 10.9 0.1 2.7 3 0 0 3 3 3 0 MSP (Major sperm protein) domain ASH PF15780.5 ORY45924.1 - 0.00016 21.8 2.3 0.13 12.4 0.3 3.5 2 2 0 2 2 2 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin SSF PF00474.17 ORY45925.1 - 1.7e-09 37.1 13.8 8e-09 34.8 13.8 1.9 1 1 0 1 1 1 1 Sodium:solute symporter family IlvGEDA_leader PF08046.11 ORY45925.1 - 0.039 13.4 0.6 0.11 11.9 0.6 1.7 1 0 0 1 1 1 0 IlvGEDA operon leader peptide DUF3980 PF13140.6 ORY45925.1 - 0.21 12.0 0.2 0.21 12.0 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3980) Clat_adaptor_s PF01217.20 ORY45927.1 - 9.6e-25 87.2 1.0 1.1e-24 86.9 1.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain F-box-like PF12937.7 ORY45928.1 - 1.7e-07 31.0 0.1 3.8e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like PP2 PF14299.6 ORY45928.1 - 0.0011 19.1 0.0 0.0049 16.9 0.0 1.9 1 1 0 1 1 1 1 Phloem protein 2 F-box PF00646.33 ORY45928.1 - 0.0079 16.1 0.1 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 F-box domain DUF2760 PF10816.8 ORY45928.1 - 0.085 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2760) NDK PF00334.19 ORY45929.1 - 1e-75 252.2 0.8 2.5e-26 92.3 0.1 6.2 4 2 2 6 6 6 5 Nucleoside diphosphate kinase Thioredoxin PF00085.20 ORY45929.1 - 0.061 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin Ion_trans PF00520.31 ORY45930.1 - 0.00076 18.8 16.2 0.0018 17.5 16.2 1.8 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 ORY45930.1 - 0.00095 17.9 7.9 0.0017 17.2 7.9 1.4 1 0 0 1 1 1 1 Polycystin cation channel DUF5455 PF17537.2 ORY45930.1 - 0.15 12.4 5.6 3.5 8.1 0.5 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5455) Ank_2 PF12796.7 ORY45931.1 - 1.5e-21 76.8 0.0 2.6e-12 47.1 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY45931.1 - 1.8e-18 66.6 1.0 3.9e-05 24.1 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY45931.1 - 4.2e-18 63.6 0.0 0.00012 22.2 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 ORY45931.1 - 1.4e-15 57.1 0.0 0.001 19.3 0.0 4.0 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY45931.1 - 1.4e-13 50.6 0.0 0.003 18.0 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat DUF4690 PF15756.5 ORY45932.1 - 0.35 11.5 2.1 0.31 11.7 0.4 1.7 2 0 0 2 2 2 0 Small Novel Rich in Cartilage EphA2_TM PF14575.6 ORY45932.1 - 0.42 11.5 1.3 0.53 11.2 0.3 1.7 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.11 ORY45932.1 - 0.53 10.4 2.3 3.1 7.9 0.0 2.1 2 0 0 2 2 2 0 Podoplanin Podoplanin PF05808.11 ORY45933.1 - 2.4 8.3 8.6 12 6.0 8.6 2.0 1 1 0 1 1 1 0 Podoplanin VSP PF03302.13 ORY45935.1 - 0.0035 16.3 0.2 0.0038 16.2 0.2 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF1180 PF06679.12 ORY45935.1 - 0.059 13.8 0.0 0.087 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Vps35 PF03635.17 ORY45937.1 - 1.5e-192 642.0 0.0 4.1e-192 640.5 0.0 1.7 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Aminotran_5 PF00266.19 ORY45938.1 - 6.5e-70 235.9 0.0 8.1e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ORY45938.1 - 9.4e-05 21.8 0.0 0.00012 21.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 ORY45938.1 - 0.02 14.3 0.0 0.028 13.7 0.0 1.1 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Mcp5_PH PF12814.7 ORY45938.1 - 0.082 13.0 0.2 0.23 11.6 0.0 1.9 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology NifU_N PF01592.16 ORY45939.1 - 1.3e-50 170.9 0.0 1.5e-50 170.6 0.0 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain zf-C2H2 PF00096.26 ORY45940.1 - 5.2e-09 36.1 8.2 0.00014 22.1 0.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY45940.1 - 3.4e-06 27.4 12.6 0.0085 16.8 2.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORY45940.1 - 0.0031 17.2 8.5 0.3 10.9 4.5 2.9 2 1 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2HE PF16278.5 ORY45940.1 - 0.027 14.9 1.5 0.31 11.5 0.5 2.4 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger C1_4 PF07975.12 ORY45940.1 - 0.039 14.2 2.5 0.052 13.8 0.6 2.3 2 1 0 2 2 2 0 TFIIH C1-like domain zf-H2C2_2 PF13465.6 ORY45940.1 - 0.064 13.7 10.2 0.24 11.9 0.1 3.7 4 0 0 4 4 4 0 Zinc-finger double domain zf-Di19 PF05605.12 ORY45940.1 - 0.089 13.1 2.5 0.18 12.1 2.3 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 ORY45940.1 - 0.2 12.0 2.6 2.7 8.4 1.8 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Nic96 PF04097.14 ORY45941.1 - 0.14 10.6 0.6 0.21 10.0 0.6 1.2 1 0 0 1 1 1 0 Nup93/Nic96 Glyco_hydro_26 PF02156.15 ORY45942.1 - 1.4e-07 31.2 3.2 0.0002 20.9 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 26 EF-hand_5 PF13202.6 ORY45942.1 - 0.0018 17.7 1.0 0.0043 16.5 1.0 1.6 1 0 0 1 1 1 1 EF hand DUF4913 PF16259.5 ORY45942.1 - 0.067 13.3 0.0 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4913) EF-hand_1 PF00036.32 ORY45942.1 - 0.16 11.6 1.5 0.41 10.3 1.5 1.7 1 0 0 1 1 1 0 EF hand MCRA PF06100.11 ORY45943.1 - 4e-189 629.5 0.0 4.5e-189 629.4 0.0 1.0 1 0 0 1 1 1 1 MCRA family NAD_binding_8 PF13450.6 ORY45943.1 - 4e-05 23.8 0.0 8.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY45943.1 - 0.015 14.9 0.0 0.07 12.7 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORY45943.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding ABC_membrane PF00664.23 ORY45944.1 - 6.3e-118 393.4 32.1 2.9e-60 204.2 9.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY45944.1 - 2.8e-71 238.4 0.1 4.2e-34 118.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY45944.1 - 1.4e-13 50.8 8.4 2.6e-05 23.8 1.8 4.6 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 ORY45944.1 - 4e-08 32.5 0.6 0.0034 16.2 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 ORY45944.1 - 7.4e-08 33.0 1.0 0.017 15.5 0.3 3.1 2 2 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 ORY45944.1 - 1.7e-07 31.4 1.3 0.032 14.0 0.1 3.7 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY45944.1 - 9.3e-07 28.5 1.9 0.0082 15.9 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 ORY45944.1 - 1.1e-06 28.9 1.2 0.24 11.7 0.2 4.1 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 ORY45944.1 - 1.5e-06 28.2 0.3 0.018 15.0 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase AAA_15 PF13175.6 ORY45944.1 - 3e-06 27.2 0.2 0.034 13.9 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 ORY45944.1 - 5.2e-06 26.3 1.6 0.036 13.8 0.4 3.5 2 2 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 ORY45944.1 - 7.6e-06 25.3 0.1 0.093 12.0 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin AAA_7 PF12775.7 ORY45944.1 - 2.4e-05 24.0 0.0 0.14 11.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 ORY45944.1 - 6.7e-05 23.4 0.0 0.063 13.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 ORY45944.1 - 0.00028 20.2 0.0 0.08 12.1 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_5 PF07728.14 ORY45944.1 - 0.00038 20.5 0.0 1.3 9.0 0.0 3.3 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA PF00004.29 ORY45944.1 - 0.00041 20.8 3.9 1.1 9.7 0.1 4.3 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ORY45944.1 - 0.00072 19.5 0.1 0.14 12.0 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain NB-ARC PF00931.22 ORY45944.1 - 0.00095 18.4 0.2 0.28 10.3 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.6 ORY45944.1 - 0.0011 18.6 0.3 1.9 8.0 0.0 3.5 4 0 0 4 4 4 1 AAA domain Dala_Dala_lig_N PF01820.21 ORY45944.1 - 0.0015 19.0 0.0 1.8 9.1 0.0 2.7 2 0 0 2 2 2 1 D-ala D-ala ligase N-terminus AAA_28 PF13521.6 ORY45944.1 - 0.0018 18.5 0.1 1.3 9.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 ORY45944.1 - 0.0019 18.4 3.5 0.48 10.7 0.4 3.8 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 ORY45944.1 - 0.0021 18.2 0.0 2.4 8.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 ORY45944.1 - 0.003 17.5 0.0 0.36 10.7 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_23 PF13476.6 ORY45944.1 - 0.0041 17.6 4.4 1.2 9.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain DUF815 PF05673.13 ORY45944.1 - 0.011 14.9 0.0 3.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 ORY45944.1 - 0.014 15.1 0.1 7.8 6.2 0.0 3.3 4 0 0 4 4 3 0 AAA domain AAA_14 PF13173.6 ORY45944.1 - 0.03 14.4 0.1 13 5.8 0.0 3.6 5 0 0 5 5 2 0 AAA domain RNA_helicase PF00910.22 ORY45944.1 - 0.032 14.6 0.0 10 6.6 0.0 2.8 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 ORY45944.1 - 0.046 13.8 0.0 7 6.7 0.0 2.8 2 0 0 2 2 2 0 Helicase HerA, central domain KAP_NTPase PF07693.14 ORY45944.1 - 0.063 12.5 0.1 0.21 10.8 0.0 1.9 2 0 0 2 2 2 0 KAP family P-loop domain MMR_HSR1 PF01926.23 ORY45944.1 - 0.065 13.3 4.4 2.5 8.2 0.0 3.9 4 0 0 4 4 3 0 50S ribosome-binding GTPase PRK PF00485.18 ORY45944.1 - 0.073 12.8 0.1 14 5.3 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.25 ORY45944.1 - 0.75 9.4 2.5 3.9 7.1 0.1 2.9 3 1 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain LRR_4 PF12799.7 ORY45948.1 - 1.3e-18 66.8 9.9 7.7e-07 29.3 0.1 3.2 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY45948.1 - 3.5e-12 45.9 3.0 1.7e-07 30.9 0.1 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 ORY45948.1 - 3e-08 33.1 0.1 0.57 10.9 0.0 4.9 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 ORY45948.1 - 8.2e-07 28.6 3.5 0.59 10.3 0.0 4.5 4 0 0 4 4 4 2 Leucine Rich repeat PAN_4 PF14295.6 ORY45948.1 - 0.0061 16.4 0.5 0.0061 16.4 0.5 2.8 2 0 0 2 2 2 1 PAN domain PAN_3 PF08277.12 ORY45948.1 - 0.087 12.7 7.0 3.6 7.5 1.0 3.9 2 0 0 2 2 2 0 PAN-like domain Utp14 PF04615.13 ORY45948.1 - 8.3 4.8 20.2 11 4.4 20.2 1.1 1 0 0 1 1 1 0 Utp14 protein KDZ PF18758.1 ORY45950.1 - 6.7e-22 78.2 0.0 1.3e-21 77.3 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase PG_binding_4 PF12229.8 ORY45951.1 - 0.0017 18.6 0.1 0.0049 17.1 0.1 1.8 1 0 0 1 1 1 1 Putative peptidoglycan binding domain DUF4041 PF13250.6 ORY45951.1 - 0.021 14.7 0.6 3.1 7.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4041) RsfS PF02410.15 ORY45952.1 - 5.7e-25 87.6 0.4 4e-24 84.9 0.0 2.3 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation Nop25 PF09805.9 ORY45952.1 - 0.0053 17.2 8.0 0.0053 17.2 8.0 2.1 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) GNAT_acetyltr_2 PF13718.6 ORY45952.1 - 0.036 13.5 1.3 0.077 12.4 1.3 1.5 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Noggin PF05806.12 ORY45952.1 - 0.25 11.2 3.1 0.51 10.2 3.1 1.5 1 0 0 1 1 1 0 Noggin His_Phos_1 PF00300.22 ORY45953.1 - 1.7e-19 70.3 0.0 8.7e-19 68.0 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) LRR_4 PF12799.7 ORY45954.1 - 7.7e-11 42.1 1.9 0.00022 21.5 0.1 4.4 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY45954.1 - 1.5e-08 34.0 6.2 0.11 13.1 0.3 6.6 6 2 1 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.6 ORY45954.1 - 2.7e-06 27.0 2.5 0.012 15.3 0.4 3.6 2 1 3 5 5 5 4 Leucine rich repeat F-box-like PF12937.7 ORY45954.1 - 6.4e-05 22.8 0.1 0.00025 20.9 0.1 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY45954.1 - 0.0028 17.5 0.0 0.015 15.2 0.1 2.1 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.6 ORY45954.1 - 0.023 14.7 0.2 27 5.2 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich repeat 7tm_3 PF00003.22 ORY45956.1 - 1.2e-10 41.5 5.1 1.6e-10 41.1 5.1 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF2461 PF09365.10 ORY45959.1 - 0.11 12.4 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein (DUF2461) SPX PF03105.19 ORY45961.1 - 0.15 12.0 4.9 0.2 11.5 4.9 1.1 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 ORY45961.1 - 1.5 7.4 4.8 1.8 7.2 4.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GATA PF00320.27 ORY45962.1 - 3.1e-11 42.7 5.1 6e-11 41.8 5.1 1.5 1 0 0 1 1 1 1 GATA zinc finger Rhodanese PF00581.20 ORY45963.1 - 2.8e-15 56.7 0.0 3.9e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Sof1 PF04158.14 ORY45964.1 - 1.1e-33 115.4 11.2 1.8e-33 114.7 11.2 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 ORY45964.1 - 1e-25 89.5 7.4 4.4e-05 24.2 0.0 6.2 6 1 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY45964.1 - 2.3e-09 37.4 0.5 0.0069 16.7 0.0 4.7 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TIMP PF00965.17 ORY45964.1 - 0.01 15.7 0.1 0.019 14.8 0.1 1.6 1 0 0 1 1 1 1 Tissue inhibitor of metalloproteinase WD40_like PF17005.5 ORY45964.1 - 0.015 14.7 0.0 1.6 8.0 0.0 3.0 2 1 1 3 3 3 0 WD40-like domain LRR_4 PF12799.7 ORY45965.1 - 2.4e-18 65.9 12.4 1.3e-06 28.6 0.2 3.8 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY45965.1 - 6.2e-15 54.7 16.6 7.1e-07 28.9 7.0 4.0 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 ORY45965.1 - 1e-09 37.6 22.5 0.24 12.1 0.2 6.6 6 0 0 6 6 6 5 Leucine Rich Repeat DUF1589 PF07628.11 ORY45965.1 - 0.0061 16.7 0.0 0.01 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1589) KinB_sensor PF16767.5 ORY45965.1 - 0.016 15.7 0.7 0.038 14.4 0.7 1.6 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB Myosin_tail_1 PF01576.19 ORY45965.1 - 0.046 11.5 0.1 0.057 11.2 0.1 1.0 1 0 0 1 1 1 0 Myosin tail CCDC144C PF14915.6 ORY45965.1 - 0.049 12.7 0.3 0.067 12.3 0.3 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region LRR_6 PF13516.6 ORY45965.1 - 0.56 10.4 11.5 34 4.8 0.1 4.8 4 0 0 4 4 4 0 Leucine Rich repeat Abhydrolase_3 PF07859.13 ORY45966.1 - 1.7e-30 106.4 0.0 8.7e-25 87.8 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY45966.1 - 0.019 13.8 0.0 2 7.2 0.1 2.2 2 0 0 2 2 2 0 Steryl acetyl hydrolase Gln-synt_C PF00120.24 ORY45966.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Glutamine synthetase, catalytic domain LRR_8 PF13855.6 ORY45968.1 - 8.5e-14 51.1 20.0 3.7e-07 29.8 4.7 5.5 4 1 1 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 ORY45968.1 - 5.4e-09 36.2 25.6 0.063 13.7 1.4 6.9 3 1 4 8 8 8 5 Leucine Rich repeats (2 copies) F-box PF00646.33 ORY45968.1 - 0.00021 21.1 0.7 0.00073 19.4 0.0 2.4 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.33 ORY45968.1 - 0.001 19.3 22.3 5.1 8.1 1.7 7.9 6 2 0 6 6 6 3 Leucine Rich Repeat Syntaxin PF00804.25 ORY45968.1 - 0.074 12.7 0.2 0.1 12.3 0.2 1.2 1 0 0 1 1 1 0 Syntaxin DUF5579 PF17742.1 ORY45969.1 - 0.042 13.4 0.3 0.078 12.5 0.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5579) Saf-Nte_pilin PF09460.10 ORY45969.1 - 0.15 12.1 0.6 0.63 10.0 0.0 2.2 3 0 0 3 3 3 0 Saf-pilin pilus formation protein 7tm_3 PF00003.22 ORY45970.1 - 3.5e-15 56.4 13.8 3.6e-14 53.1 13.8 2.0 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.14 ORY45970.1 - 4.9e-11 42.2 0.0 7e-11 41.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like Kelch_5 PF13854.6 ORY45970.1 - 1.5e-07 31.2 0.2 0.011 15.7 0.0 2.9 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 ORY45970.1 - 4.7e-07 29.7 1.2 5e-05 23.2 0.0 3.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_3 PF13415.6 ORY45970.1 - 0.00021 21.5 2.0 3.5 8.0 0.0 4.8 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY45970.1 - 0.006 16.8 0.2 0.43 10.9 0.0 3.2 3 0 0 3 3 3 1 Kelch motif Dynein_IC2 PF11540.8 ORY45970.1 - 1.5 8.8 4.4 11 6.0 0.1 2.5 2 0 0 2 2 2 0 Cytoplasmic dynein 1 intermediate chain 2 NEMP PF10225.9 ORY45970.1 - 7.6 6.1 8.2 0.24 11.1 1.4 1.8 2 0 0 2 2 2 0 NEMP family gag-asp_proteas PF13975.6 ORY45971.1 - 0.0012 19.3 0.0 0.0034 17.9 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 ORY45971.1 - 0.0015 19.1 0.1 0.0061 17.2 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease LRR_8 PF13855.6 ORY45972.1 - 1.5e-22 79.1 27.6 2.4e-06 27.2 7.0 6.9 4 2 3 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 ORY45972.1 - 5.6e-20 71.1 27.1 6.3e-05 23.3 3.7 8.6 3 2 5 10 10 10 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY45972.1 - 4.1e-08 32.7 36.6 2.3 9.1 0.8 12.5 12 1 1 13 13 13 3 Leucine Rich Repeat F-box-like PF12937.7 ORY45972.1 - 0.13 12.1 0.1 0.37 10.7 0.1 1.8 1 0 0 1 1 1 0 F-box-like SBF_like PF13593.6 ORY45973.1 - 7.8e-90 301.3 18.5 9.1e-90 301.1 18.5 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 ORY45973.1 - 2.9e-08 33.6 11.3 2.9e-08 33.6 11.3 2.0 2 0 0 2 2 2 1 Sodium Bile acid symporter family Rnf-Nqr PF02508.14 ORY45973.1 - 0.32 11.0 14.2 0.23 11.4 2.6 3.2 1 1 2 3 3 3 0 Rnf-Nqr subunit, membrane protein Deltameth_res PF16020.5 ORY45973.1 - 1.1 9.1 5.0 14 5.6 0.0 3.3 2 1 1 3 3 3 0 Deltamethrin resistance MacB_PCD PF12704.7 ORY45974.1 - 0.0027 18.1 0.0 0.0033 17.8 0.0 1.1 1 0 0 1 1 1 1 MacB-like periplasmic core domain DUF5630 PF18632.1 ORY45974.1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5630) DUF515 PF04415.12 ORY45974.1 - 4.4 5.6 6.1 4.8 5.5 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) RAP1 PF07218.11 ORY45974.1 - 4.4 5.5 9.7 4.9 5.3 9.7 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF5572 PF17733.1 ORY45975.1 - 6.2e-18 64.4 0.0 1.4e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5572) ABC_membrane PF00664.23 ORY45978.1 - 6.7e-62 209.6 26.9 4.1e-37 128.3 9.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY45978.1 - 8.8e-49 165.5 0.3 5.4e-29 101.4 0.0 2.7 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 ORY45978.1 - 2e-09 37.3 2.7 0.068 12.6 0.0 4.4 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY45978.1 - 1e-07 32.0 0.1 0.028 14.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY45978.1 - 1.2e-07 31.3 0.5 0.0046 16.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 ORY45978.1 - 1.5e-07 31.6 0.1 0.089 12.6 0.0 3.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ORY45978.1 - 1.7e-07 31.9 1.8 0.0053 17.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 ORY45978.1 - 1.2e-05 25.7 0.1 0.19 12.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.18 ORY45978.1 - 1.5e-05 24.5 0.4 0.021 14.2 0.0 2.7 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_22 PF13401.6 ORY45978.1 - 2.1e-05 24.8 0.4 0.32 11.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain NACHT PF05729.12 ORY45978.1 - 2.1e-05 24.5 0.1 0.022 14.7 0.0 2.8 2 0 0 2 2 2 1 NACHT domain RsgA_GTPase PF03193.16 ORY45978.1 - 2.5e-05 24.2 0.2 0.027 14.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 ORY45978.1 - 0.00017 21.7 3.5 0.092 12.8 0.0 2.8 3 0 0 3 3 2 2 Dynamin family T2SSE PF00437.20 ORY45978.1 - 0.0023 17.0 0.0 1.4 7.9 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein RNA_helicase PF00910.22 ORY45978.1 - 0.0024 18.2 0.0 5.9 7.3 0.0 3.4 3 0 0 3 3 3 0 RNA helicase DUF87 PF01935.17 ORY45978.1 - 0.0066 16.6 5.0 0.092 12.8 0.2 2.6 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_15 PF13175.6 ORY45978.1 - 0.0078 16.0 1.3 2.1 7.9 0.0 2.4 3 0 0 3 3 2 1 AAA ATPase domain cobW PF02492.19 ORY45978.1 - 0.0079 15.8 3.5 0.26 10.9 0.0 3.5 4 0 0 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain Ploopntkinase3 PF18751.1 ORY45978.1 - 0.015 15.3 0.0 8.9 6.2 0.0 2.8 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 AAA_10 PF12846.7 ORY45978.1 - 0.023 13.6 0.1 0.28 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.6 ORY45978.1 - 0.025 15.1 0.0 16 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 ORY45978.1 - 0.03 13.2 0.8 2.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.17 ORY45978.1 - 0.031 14.1 0.0 4.2 7.1 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 ORY45978.1 - 0.033 13.7 0.2 3.8 7.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 ORY45978.1 - 0.035 13.3 0.1 8.4 5.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 ORY45978.1 - 0.038 13.7 0.1 9.3 5.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 ORY45978.1 - 0.039 12.9 0.3 2.9 6.8 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Zeta_toxin PF06414.12 ORY45978.1 - 0.07 12.4 0.1 6.3 6.0 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin ABC_ATPase PF09818.9 ORY45978.1 - 0.082 11.7 0.7 2.1 7.0 0.0 2.7 3 0 0 3 3 3 0 Predicted ATPase of the ABC class ATP-synt_ab PF00006.25 ORY45978.1 - 0.11 12.1 0.0 13 5.3 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.14 ORY45978.1 - 0.14 12.1 0.2 8.1 6.4 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Roc PF08477.13 ORY45978.1 - 0.17 12.1 2.2 8.8 6.6 0.1 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Adeno_IVa2 PF02456.15 ORY45978.1 - 0.17 10.6 0.5 5.7 5.6 0.0 2.5 3 0 0 3 3 3 0 Adenovirus IVa2 protein AAA_33 PF13671.6 ORY45978.1 - 0.21 11.7 0.2 14 5.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain Pex2_Pex12 PF04757.14 ORY45979.1 - 4.8e-23 81.9 0.3 5.8e-23 81.7 0.3 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 ORY45979.1 - 7.9e-08 32.0 1.5 1.7e-07 31.0 1.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY45979.1 - 4.4e-06 26.5 1.0 7.6e-06 25.7 1.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY45979.1 - 4.6e-05 23.2 1.6 9.2e-05 22.2 1.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY45979.1 - 7.8e-05 22.8 5.5 0.00018 21.6 5.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 ORY45979.1 - 9.3e-05 22.7 2.0 0.00019 21.7 2.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 ORY45979.1 - 0.00075 19.5 4.3 0.0016 18.4 4.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger DZR PF12773.7 ORY45979.1 - 0.003 17.6 0.4 0.0056 16.7 0.4 1.4 1 0 0 1 1 1 1 Double zinc ribbon DAZAP2 PF11029.8 ORY45979.1 - 0.14 13.1 1.4 0.28 12.1 1.1 1.6 1 1 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) zinc_ribbon_2 PF13240.6 ORY45979.1 - 0.16 11.8 0.3 0.34 10.7 0.1 1.6 2 0 0 2 2 2 0 zinc-ribbon domain LRR_8 PF13855.6 ORY45980.1 - 3.7e-29 100.3 45.9 8.6e-09 35.0 3.8 7.6 6 1 0 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 ORY45980.1 - 7.5e-22 77.1 46.5 0.005 17.2 1.9 9.3 5 2 5 10 10 10 9 Leucine Rich repeats (2 copies) F-box PF00646.33 ORY45980.1 - 5.4e-11 42.1 3.4 6.8e-05 22.6 0.4 2.9 2 0 0 2 2 2 2 F-box domain LRR_1 PF00560.33 ORY45980.1 - 3.6e-09 35.9 43.5 3.1 8.7 0.2 12.9 12 0 0 12 12 12 5 Leucine Rich Repeat F-box-like PF12937.7 ORY45980.1 - 6.2e-06 26.0 1.2 0.0038 17.1 0.1 2.7 2 0 0 2 2 2 2 F-box-like LRR_2 PF07723.13 ORY45980.1 - 2.2e-05 24.9 0.7 53 4.7 0.0 6.1 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_9 PF14580.6 ORY45980.1 - 0.44 10.0 14.2 2.8 7.4 0.3 4.5 2 2 3 5 5 5 0 Leucine-rich repeat Lung_7-TM_R PF06814.13 ORY45981.1 - 1.1e-64 218.6 18.2 1.1e-64 218.6 18.2 1.4 2 0 0 2 2 2 1 Lung seven transmembrane receptor Lung_7-TM_R PF06814.13 ORY45982.1 - 1.3e-63 215.0 20.3 1.5e-63 214.8 20.3 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor Glyoxalase PF00903.25 ORY45983.1 - 1.2e-20 74.0 0.1 1.1e-14 54.7 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ORY45983.1 - 1.4e-10 41.4 0.0 0.00049 20.4 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 ORY45983.1 - 1.9e-07 31.3 0.1 1.6e-06 28.4 0.1 2.1 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 ORY45983.1 - 2.7e-05 24.3 0.0 0.043 13.9 0.0 2.9 1 1 1 2 2 2 2 Glyoxalase-like domain PikAIV_N PF18605.1 ORY45984.1 - 0.0001 21.8 14.1 0.017 14.7 5.5 3.1 2 1 0 2 2 2 2 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain TolA_bind_tri PF16331.5 ORY45984.1 - 0.0011 19.1 36.8 0.0019 18.2 10.7 5.0 4 1 0 4 4 4 1 TolA binding protein trimerisation ZapB PF06005.12 ORY45984.1 - 0.0013 19.1 9.6 0.0013 19.1 9.6 4.7 3 1 0 3 3 2 1 Cell division protein ZapB Phage_GP20 PF06810.11 ORY45984.1 - 0.0017 18.1 6.8 0.0017 18.1 6.8 3.4 3 1 0 3 3 3 1 Phage minor structural protein GP20 Cnn_1N PF07989.11 ORY45984.1 - 0.0045 17.1 6.5 0.0045 17.1 6.5 3.8 3 1 0 3 3 3 2 Centrosomin N-terminal motif 1 Shugoshin_N PF07558.11 ORY45984.1 - 0.0052 16.6 26.0 0.056 13.3 5.7 4.7 4 0 0 4 4 4 2 Shugoshin N-terminal coiled-coil region APG6_N PF17675.1 ORY45984.1 - 0.016 15.7 38.2 0.017 15.6 9.9 3.3 2 1 0 3 3 3 0 Apg6 coiled-coil region YabA PF06156.13 ORY45984.1 - 0.033 14.8 6.3 0.033 14.8 6.3 3.8 2 1 1 3 3 3 0 Initiation control protein YabA GIT_CC PF16559.5 ORY45984.1 - 0.033 14.0 6.3 0.033 14.0 6.3 4.6 4 1 0 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.21 ORY45984.1 - 0.037 14.1 4.7 0.037 14.1 4.7 5.2 4 1 1 5 5 5 0 bZIP transcription factor CCDC92 PF14916.6 ORY45984.1 - 0.04 13.7 0.7 0.04 13.7 0.7 3.8 4 0 0 4 4 4 0 Coiled-coil domain of unknown function Cep57_CLD_2 PF14197.6 ORY45984.1 - 0.042 13.9 33.7 0.46 10.6 5.2 4.1 4 0 0 4 4 4 0 Centrosome localisation domain of PPC89 DUF3208 PF11482.8 ORY45984.1 - 0.062 13.6 0.7 0.062 13.6 0.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3208) Mod_r PF07200.13 ORY45984.1 - 0.17 12.0 34.6 0.057 13.5 11.4 3.2 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein ATG16 PF08614.11 ORY45984.1 - 0.31 11.3 42.5 0.097 12.9 14.0 3.7 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) HALZ PF02183.18 ORY45984.1 - 0.39 11.0 27.6 0.11 12.7 5.0 4.7 5 0 0 5 5 5 0 Homeobox associated leucine zipper PKcGMP_CC PF16808.5 ORY45984.1 - 0.44 10.4 8.6 4.1 7.4 0.1 3.9 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase bZIP_2 PF07716.15 ORY45984.1 - 1.2 9.2 34.1 0.34 11.0 7.4 5.1 4 1 1 5 5 5 0 Basic region leucine zipper TPR_MLP1_2 PF07926.12 ORY45984.1 - 1.2 9.2 41.6 2.6 8.1 14.1 3.3 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein HAP1_N PF04849.13 ORY45984.1 - 1.3 8.2 33.4 0.022 14.0 18.8 3.2 2 1 1 3 3 3 0 HAP1 N-terminal conserved region CCDC-167 PF15188.6 ORY45984.1 - 1.5 9.2 22.2 15 6.0 1.3 3.9 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 DUF5101 PF17031.5 ORY45984.1 - 1.6 8.8 11.4 0.54 10.4 0.8 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF5101) Lebercilin PF15619.6 ORY45984.1 - 1.7 8.3 39.6 0.13 11.9 10.7 3.6 3 1 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease DUF3450 PF11932.8 ORY45984.1 - 1.7 7.9 35.8 0.19 11.0 8.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) FemAB PF02388.16 ORY45984.1 - 3.3 6.5 17.0 2.7 6.8 6.4 2.2 1 1 1 2 2 2 0 FemAB family MAD PF05557.13 ORY45984.1 - 3.4 5.9 33.4 0.036 12.4 9.9 3.0 2 1 1 3 3 3 0 Mitotic checkpoint protein Uso1_p115_C PF04871.13 ORY45984.1 - 3.8 7.9 34.4 3.5 8.0 10.2 3.1 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4407 PF14362.6 ORY45984.1 - 3.9 6.7 25.3 4.1e+02 0.1 25.3 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.8 ORY45984.1 - 6.2 6.9 36.4 13 5.8 8.3 3.7 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding FlxA PF14282.6 ORY45984.1 - 6.9 6.7 40.4 4.8 7.2 15.3 3.5 3 0 0 3 3 3 0 FlxA-like protein Smr PF01713.21 ORY45985.1 - 1.3e-11 44.7 0.0 2e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.10 ORY45985.1 - 9e-05 22.8 1.7 0.00012 22.4 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Aldedh PF00171.22 ORY45986.1 - 1.1e-137 459.3 0.0 1.3e-137 459.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 ORY45986.1 - 0.0072 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) LZ3wCH PF18517.1 ORY45986.1 - 0.23 11.6 0.3 0.46 10.6 0.3 1.5 1 0 0 1 1 1 0 Leucine zipper with capping helix domain RasGAP PF00616.19 ORY45987.1 - 2.7e-39 135.0 0.0 5.1e-39 134.1 0.0 1.4 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase Nse5 PF08691.10 ORY45987.1 - 0.001 17.8 0.0 0.0021 16.8 0.0 1.4 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 WD40 PF00400.32 ORY45988.1 - 5.4e-14 52.4 9.4 0.0053 17.6 0.1 6.4 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY45988.1 - 9.5e-11 41.9 0.1 0.00085 19.6 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.21 ORY45988.1 - 0.015 14.1 1.9 0.018 13.8 0.5 1.8 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.11 ORY45988.1 - 0.029 14.3 0.2 0.28 11.1 0.0 2.5 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 ORY45988.1 - 0.038 12.0 0.4 0.12 10.4 0.4 1.8 1 1 0 1 1 1 0 IKI3 family AA_permease PF00324.21 ORY45989.1 - 1.2e-109 367.0 45.1 1.5e-109 366.8 45.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY45989.1 - 4.2e-33 114.8 49.9 5e-33 114.6 49.9 1.1 1 0 0 1 1 1 1 Amino acid permease SWIB PF02201.18 ORY45990.1 - 1.1e-22 79.7 0.5 1.1e-22 79.7 0.5 2.2 2 0 0 2 2 2 1 SWIB/MDM2 domain IBR PF01485.21 ORY45991.1 - 5.4e-17 61.8 36.7 8.5e-10 38.7 1.3 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 ORY45991.1 - 9.7e-05 22.3 4.0 9.7e-05 22.3 4.0 3.9 3 1 0 3 3 3 2 RING-type zinc-finger zf-RING_2 PF13639.6 ORY45991.1 - 0.00025 21.3 40.1 0.00083 19.6 5.1 4.3 3 1 1 4 4 4 2 Ring finger domain zf-C3HC4_2 PF13923.6 ORY45991.1 - 0.00026 20.8 1.5 0.00026 20.8 1.5 5.0 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY45991.1 - 0.00028 20.7 5.7 0.00028 20.7 5.7 4.8 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY45991.1 - 0.0088 16.0 5.2 0.0088 16.0 5.2 4.5 3 2 0 3 3 3 1 zinc-RING finger domain zf-RING_4 PF14570.6 ORY45991.1 - 2.3 8.1 33.6 3.4 7.5 5.3 3.7 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 ORY45991.1 - 2.4 8.4 35.5 0.17 12.1 6.3 4.4 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING LRR_8 PF13855.6 ORY45993.1 - 5.8e-20 70.8 13.3 9.3e-07 28.5 5.1 3.8 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY45993.1 - 6.3e-09 36.0 21.6 0.00023 21.5 0.6 4.7 1 1 6 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY45993.1 - 1.3e-06 28.1 20.1 0.3 11.8 0.0 7.1 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 ORY45993.1 - 7.3e-06 25.6 11.0 0.08 13.0 0.1 5.4 7 0 0 7 7 7 2 Leucine Rich repeat F-box PF00646.33 ORY45993.1 - 2.7e-05 23.9 0.4 6.4e-05 22.7 0.4 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY45993.1 - 0.00017 21.4 0.6 0.00017 21.4 0.6 2.5 3 0 0 3 3 3 1 F-box-like LRR_9 PF14580.6 ORY45993.1 - 0.18 11.3 3.0 1.9 8.0 0.6 2.2 1 1 2 3 3 3 0 Leucine-rich repeat IBR PF01485.21 ORY45994.1 - 4.8e-21 74.7 42.4 2.1e-13 50.3 2.3 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 ORY45994.1 - 4.1e-05 23.4 37.6 0.00017 21.4 2.0 4.7 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY45994.1 - 0.00064 19.5 2.2 0.00064 19.5 2.2 5.7 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY45994.1 - 0.0013 18.8 30.1 0.0051 16.9 2.9 4.2 3 1 0 3 3 3 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 ORY45994.1 - 0.0024 17.9 30.4 0.0032 17.5 2.0 4.2 3 1 0 3 3 3 2 RING-type zinc-finger DUF2953 PF11167.8 ORY45994.1 - 0.2 11.8 0.2 0.49 10.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) zf-RING_2 PF13639.6 ORY45994.1 - 5.1 7.5 49.3 0.075 13.4 4.4 4.9 3 1 1 4 4 4 0 Ring finger domain Ribosom_S12_S23 PF00164.25 ORY45997.1 - 1.1e-50 170.0 0.4 1.4e-50 169.7 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Hpt PF01627.23 ORY45998.1 - 1.5e-13 50.8 0.1 2.1e-13 50.4 0.1 1.2 1 0 0 1 1 1 1 Hpt domain CMS1 PF14617.6 ORY45999.1 - 5.4e-16 58.7 14.9 9.9e-15 54.6 14.9 2.2 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 ORY45999.1 - 0.00062 19.6 0.1 0.00072 19.4 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF908 PF06012.12 ORY45999.1 - 1.3 8.4 4.3 1.8 7.9 4.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Response_reg PF00072.24 ORY46000.1 - 2.6e-38 130.6 1.7 6.4e-18 64.9 0.0 2.4 2 0 0 2 2 2 2 Response regulator receiver domain Josephin PF02099.17 ORY46001.1 - 1.2e-44 152.3 0.0 1.7e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Josephin UIM PF02809.20 ORY46001.1 - 1.3e-07 31.0 5.8 0.0041 16.9 0.9 2.7 2 0 0 2 2 2 2 Ubiquitin interaction motif Pyrophosphatase PF00719.19 ORY46002.1 - 3.2e-58 196.1 0.3 4.4e-58 195.6 0.3 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Elongin_A PF06881.11 ORY46002.1 - 0.061 13.8 0.1 0.16 12.5 0.0 1.7 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A LRR_4 PF12799.7 ORY46003.1 - 2.9e-23 81.6 43.6 6.4e-06 26.4 1.0 8.5 5 1 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY46003.1 - 4.5e-23 80.8 47.7 2e-07 30.7 1.0 6.6 5 2 2 7 7 7 5 Leucine rich repeat F-box PF00646.33 ORY46003.1 - 1.1e-06 28.3 0.0 3e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.6 ORY46003.1 - 6.4e-06 25.8 41.7 0.23 11.6 0.0 12.0 14 0 0 14 14 14 4 Leucine Rich repeat LRR_1 PF00560.33 ORY46003.1 - 2.5e-05 24.2 48.8 6 7.8 0.2 13.2 13 1 1 14 14 14 4 Leucine Rich Repeat F-box-like PF12937.7 ORY46003.1 - 0.011 15.7 0.0 0.03 14.2 0.0 1.8 1 0 0 1 1 1 0 F-box-like bZIP_1 PF00170.21 ORY46003.1 - 0.11 12.6 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 bZIP transcription factor LRR_2 PF07723.13 ORY46003.1 - 0.27 12.0 2.0 8.1 7.3 0.0 4.1 5 0 0 5 5 5 0 Leucine Rich Repeat Peptidase_M24 PF00557.24 ORY46004.1 - 6.3e-43 146.9 0.1 9.3e-43 146.3 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF643 PF04867.12 ORY46004.1 - 0.1 13.2 4.4 0.31 11.7 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF643) TFIIF_alpha PF05793.12 ORY46004.1 - 0.11 11.1 4.9 0.15 10.6 4.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3391 PF11871.8 ORY46004.1 - 0.14 12.6 2.0 0.3 11.6 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) Cadherin_tail PF15974.5 ORY46004.1 - 0.8 10.0 3.9 9.5 6.6 4.3 2.1 2 0 0 2 2 2 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region DnaJ PF00226.31 ORY46005.1 - 9.4e-24 83.3 2.5 1.6e-23 82.6 0.2 2.1 2 0 0 2 2 2 1 DnaJ domain LRR_4 PF12799.7 ORY46006.1 - 2.1e-13 50.2 16.1 1.7e-05 25.1 0.6 4.4 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY46006.1 - 3.2e-13 49.2 15.9 7.4e-08 32.0 2.1 3.7 2 1 2 4 4 4 3 Leucine rich repeat F-box PF00646.33 ORY46006.1 - 4.6e-06 26.4 0.1 1.3e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY46006.1 - 0.00061 19.6 0.3 0.0018 18.2 0.3 1.8 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 ORY46006.1 - 0.0017 18.7 19.4 4.6 8.2 0.1 6.7 7 1 1 8 8 8 1 Leucine Rich Repeat Dict-STAT-coil PF09267.10 ORY46006.1 - 0.024 15.0 0.6 14 6.1 0.1 2.9 1 1 0 2 2 2 0 Dictyostelium STAT, coiled coil DUF5612 PF18462.1 ORY46006.1 - 0.24 11.2 0.0 4.7 7.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5612) DUF3338 PF11819.8 ORY46006.1 - 0.33 10.9 1.1 10 6.1 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3338) LRR_8 PF13855.6 ORY46007.1 - 4.6e-14 51.9 34.6 2.3e-05 24.1 3.7 5.3 2 2 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 ORY46007.1 - 8.2e-14 51.5 30.4 0.00031 21.1 1.0 5.4 2 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY46007.1 - 1.1e-05 25.3 34.8 0.23 12.1 0.2 8.8 10 0 0 10 10 10 4 Leucine Rich Repeat LRR_2 PF07723.13 ORY46007.1 - 0.00081 19.9 3.5 7.6 7.4 0.0 4.9 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.6 ORY46007.1 - 0.11 12.6 0.4 0.11 12.6 0.4 6.3 7 0 0 7 7 7 0 Leucine Rich repeat WDCP PF15390.6 ORY46008.1 - 0.00065 18.2 0.2 0.00076 18.0 0.2 1.2 1 0 0 1 1 1 1 WD repeat and coiled-coil-containing protein family Sulfate_transp PF00916.20 ORY46009.1 - 3e-88 296.2 25.4 4e-88 295.7 25.4 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORY46009.1 - 2e-11 43.5 0.0 4.9e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 STAS domain Na_H_antiport_2 PF13726.6 ORY46009.1 - 0.0061 16.7 0.5 0.0061 16.7 0.5 2.5 2 0 0 2 2 2 1 Na+-H+ antiporter family MFS_MOT1 PF16983.5 ORY46009.1 - 0.012 16.0 17.9 0.27 11.6 4.5 3.0 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 ORY46009.1 - 0.034 14.5 0.0 0.076 13.4 0.0 1.6 1 0 0 1 1 1 0 STAS domain TatD_DNase PF01026.21 ORY46011.1 - 0.00046 19.6 0.1 0.00059 19.3 0.1 1.1 1 0 0 1 1 1 1 TatD related DNase RNase_H PF00075.24 ORY46012.1 - 3.2e-08 33.9 0.0 9.9e-08 32.3 0.0 1.9 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.6 ORY46012.1 - 0.00038 21.1 0.6 0.0014 19.3 0.6 2.0 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Pkinase PF00069.25 ORY46013.1 - 4.2e-24 85.3 0.0 4.4e-24 85.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY46013.1 - 3.5e-08 33.0 0.0 3.7e-08 33.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY46013.1 - 0.0017 17.2 0.0 0.0018 17.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY46013.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.3 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 ORY46013.1 - 0.083 12.2 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 ORY46013.1 - 0.094 11.7 0.1 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase LIM PF00412.22 ORY46015.1 - 1.3e-23 83.0 24.5 1.5e-12 47.5 6.1 2.2 2 0 0 2 2 2 2 LIM domain Lar_restr_allev PF14354.6 ORY46015.1 - 0.013 15.8 1.3 0.013 15.8 1.3 3.1 2 2 1 3 3 3 0 Restriction alleviation protein Lar zf_UBZ PF18439.1 ORY46015.1 - 0.032 13.8 16.7 0.69 9.6 0.6 4.4 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Zn-ribbon_8 PF09723.10 ORY46015.1 - 0.28 11.3 24.9 1.8 8.8 4.0 3.9 4 0 0 4 4 4 0 Zinc ribbon domain Mito_carr PF00153.27 ORY46016.1 - 7.8e-63 208.4 1.2 5.1e-21 74.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UPF0029 PF01205.19 ORY46017.1 - 6.2e-28 97.2 0.0 1.3e-27 96.2 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Sec2p PF06428.11 ORY46017.1 - 0.018 15.0 1.8 0.035 14.1 1.8 1.5 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p NPA PF16469.5 ORY46017.1 - 0.091 13.3 1.3 0.17 12.5 1.3 1.4 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 TPD52 PF04201.15 ORY46017.1 - 0.13 11.8 2.5 0.3 10.7 2.5 1.6 1 0 0 1 1 1 0 Tumour protein D52 family Tho2 PF11262.8 ORY46018.1 - 0.029 13.6 2.2 0.05 12.8 2.2 1.3 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 LIF_OSM PF01291.17 ORY46018.1 - 0.044 13.9 0.1 0.092 12.9 0.1 1.5 1 0 0 1 1 1 0 LIF / OSM family TPR_MLP1_2 PF07926.12 ORY46018.1 - 0.22 11.6 10.6 0.43 10.7 10.6 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein YebO PF13974.6 ORY46018.1 - 2.2 8.4 6.2 2 8.6 2.4 2.5 2 0 0 2 2 2 0 YebO-like protein Fe-ADH PF00465.19 ORY46020.1 - 0.069 12.0 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase CHS5_N PF16892.5 ORY46021.1 - 0.7 9.9 4.7 2.5e+02 1.7 0.0 4.6 4 0 0 4 4 4 0 Chitin biosynthesis protein CHS5 N-terminus SH PF01445.17 ORY46021.1 - 0.98 9.4 9.5 80 3.3 0.1 4.2 4 0 0 4 4 4 0 Viral small hydrophobic protein Enkurin PF13864.6 ORY46022.1 - 2.8e-14 53.3 4.8 2.8e-14 53.3 4.8 2.7 2 0 0 2 2 2 1 Calmodulin-binding Allexi_40kDa PF05549.11 ORY46022.1 - 1.8 8.0 5.8 2.8 7.4 0.1 2.5 2 0 0 2 2 2 0 Allexivirus 40kDa protein Elf1 PF05129.13 ORY46023.1 - 0.04 14.0 0.2 0.098 12.7 0.2 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Phage_P2_GpU PF06995.11 ORY46023.1 - 0.044 13.4 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 Phage P2 GpU 2OG-FeII_Oxy_2 PF13532.6 ORY46024.1 - 3.7e-13 50.1 0.0 4.7e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Mito_carr PF00153.27 ORY46025.1 - 8.1e-21 73.8 10.2 3.9e-12 45.9 0.3 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein FH2 PF02181.23 ORY46026.1 - 5.5e-76 256.1 1.8 5.5e-76 256.1 1.8 2.0 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 ORY46026.1 - 4e-09 36.4 2.7 1.5e-08 34.5 0.0 2.9 3 0 0 3 3 3 1 Diaphanous FH3 Domain DUF3450 PF11932.8 ORY46026.1 - 0.11 11.8 4.0 0.064 12.6 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) XPG_I PF00867.18 ORY46027.1 - 3.3e-15 56.2 0.0 6.1e-12 45.7 0.0 2.5 2 0 0 2 2 2 2 XPG I-region XPG_N PF00752.17 ORY46027.1 - 6.4e-05 23.4 0.0 0.00017 22.0 0.0 1.8 1 1 0 1 1 1 1 XPG N-terminal domain Asn_synthase PF00733.21 ORY46028.1 - 2.8e-14 53.6 0.1 4.9e-11 42.9 0.1 2.2 1 1 1 2 2 2 2 Asparagine synthase DZR PF12773.7 ORY46028.1 - 0.022 14.8 0.5 0.039 14.0 0.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 ORY46028.1 - 0.31 10.8 4.0 0.54 10.1 4.0 1.4 1 0 0 1 1 1 0 zinc-ribbon domain XPG_I PF00867.18 ORY46031.1 - 1.8e-10 41.0 0.0 3e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 ORY46031.1 - 8.4e-10 39.0 0.0 1.5e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain Glyco_transf_8 PF01501.20 ORY46037.1 - 5.3e-11 42.6 2.8 4.7e-06 26.4 0.0 3.2 2 1 0 2 2 2 2 Glycosyl transferase family 8 DPM3 PF08285.11 ORY46038.1 - 8.4e-30 102.8 0.1 9.1e-30 102.7 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) FH2 PF02181.23 ORY46039.1 - 7.6e-47 160.2 0.1 8.3e-47 160.1 0.1 1.0 1 0 0 1 1 1 1 Formin Homology 2 Domain TBCC_N PF16752.5 ORY46039.1 - 0.03 14.8 0.3 0.064 13.7 0.1 1.7 1 1 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain Radical_SAM PF04055.21 ORY46039.1 - 0.098 13.0 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Radical SAM superfamily Drf_FH3 PF06367.16 ORY46040.1 - 2.2e-05 24.2 0.0 6.5e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Diaphanous FH3 Domain DUF3450 PF11932.8 ORY46041.1 - 7.3e-05 22.2 22.4 0.011 15.1 5.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3450) Cnn_1N PF07989.11 ORY46041.1 - 0.013 15.7 5.9 0.013 15.7 5.9 3.7 3 2 0 3 3 3 0 Centrosomin N-terminal motif 1 GIT_CC PF16559.5 ORY46041.1 - 0.086 12.7 17.9 0.49 10.3 5.5 3.8 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF4407 PF14362.6 ORY46041.1 - 0.1 11.9 13.7 0.17 11.2 13.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YojJ PF10372.9 ORY46041.1 - 0.72 10.0 3.5 1 9.5 1.1 2.5 1 1 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus DUF1664 PF07889.12 ORY46041.1 - 3 7.9 16.1 0.16 12.0 1.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) ERM PF00769.19 ORY46041.1 - 3.9 7.2 29.0 3.8 7.2 24.5 2.5 2 1 0 2 2 2 0 Ezrin/radixin/moesin family UPF0449 PF15136.6 ORY46041.1 - 4.1 7.9 22.2 9.3 6.8 5.0 3.4 2 1 1 3 3 3 0 Uncharacterised protein family UPF0449 CHD5 PF04420.14 ORY46041.1 - 8.4 6.2 11.4 14 5.5 10.5 1.9 1 1 0 1 1 1 0 CHD5-like protein YabA PF06156.13 ORY46041.1 - 8.5 7.1 30.5 0.25 12.0 7.0 3.8 2 1 2 4 4 4 0 Initiation control protein YabA Glyco_hydro_19 PF00182.19 ORY46043.1 - 1.3e-10 41.6 1.7 1.8e-10 41.1 0.5 1.6 1 1 0 1 1 1 1 Chitinase class I Loricrin PF15847.5 ORY46043.1 - 0.011 14.8 21.1 0.019 14.1 21.1 1.3 1 0 0 1 1 1 0 Major keratinocyte cell envelope protein PG_binding_1 PF01471.18 ORY46043.1 - 0.02 15.1 0.3 10 6.4 0.0 2.8 2 1 0 2 2 2 0 Putative peptidoglycan binding domain Phage_lysozyme2 PF18013.1 ORY46043.1 - 2.8 8.0 5.8 0.54 10.2 0.4 2.3 2 0 0 2 2 2 0 Phage tail lysozyme HEAT PF02985.22 ORY46044.1 - 0.00015 21.7 0.1 6.4 7.3 0.0 6.2 5 0 0 5 5 5 2 HEAT repeat SKG6 PF08693.10 ORY46045.1 - 0.023 14.1 0.8 0.056 12.9 0.8 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TFIIA PF03153.13 ORY46045.1 - 4.5 7.2 14.2 5.7 6.8 14.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mito_carr PF00153.27 ORY46046.1 - 5e-06 26.4 0.1 0.0013 18.6 0.0 2.9 3 1 0 3 3 3 2 Mitochondrial carrier protein RRM_1 PF00076.22 ORY46048.1 - 3.2e-07 30.1 0.8 2.1e-06 27.4 0.8 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.24 ORY46048.1 - 6.4e-07 29.1 0.5 6.4e-07 29.1 0.5 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY46048.1 - 0.0011 18.9 1.0 0.0028 17.7 1.0 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 ORY46048.1 - 0.0044 16.8 1.6 0.012 15.4 1.6 1.8 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 ORY46048.1 - 0.0066 17.1 0.0 0.014 16.1 0.0 1.5 1 0 0 1 1 1 1 Torus domain zf-C2H2_4 PF13894.6 ORY46049.1 - 0.0022 18.7 2.0 0.23 12.4 0.3 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORY46049.1 - 0.0046 17.1 0.6 0.28 11.3 0.1 2.3 2 0 0 2 2 2 1 Aberrant zinc-finger zf-C2H2 PF00096.26 ORY46049.1 - 0.012 16.0 2.3 1 9.9 0.2 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-BED PF02892.15 ORY46049.1 - 0.015 15.3 3.5 0.49 10.5 0.2 2.5 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.6 ORY46049.1 - 0.12 12.4 0.1 0.12 12.4 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Oxidored-like PF09791.9 ORY46050.1 - 2.4e-15 55.9 3.8 4.1e-15 55.2 3.8 1.3 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 ORY46050.1 - 0.015 15.2 2.4 0.029 14.3 2.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5522) Med3 PF11593.8 ORY46050.1 - 8.1 5.5 6.8 8.8 5.4 6.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal OPT PF03169.15 ORY46051.1 - 8.7e-108 361.6 57.5 1e-107 361.3 57.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3274 PF11678.8 ORY46052.1 - 0.045 13.0 0.1 0.069 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3274) GEN1_C PF18380.1 ORY46052.1 - 3.1 8.7 5.3 5 8.1 0.5 2.6 2 1 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Anoct_dimer PF16178.5 ORY46053.1 - 0.071 12.8 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin YqfD PF06898.11 ORY46053.1 - 0.14 11.0 0.1 0.18 10.6 0.1 1.1 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD AMP-binding PF00501.28 ORY46054.1 - 6.9e-85 285.2 0.1 9.7e-85 284.7 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY46054.1 - 0.0083 17.1 1.6 0.027 15.4 0.9 2.1 1 1 1 2 2 2 1 AMP-binding enzyme C-terminal domain BLUF PF04940.12 ORY46055.1 - 0.022 14.9 0.1 0.065 13.4 0.1 1.8 1 0 0 1 1 1 0 Sensors of blue-light using FAD APG6_N PF17675.1 ORY46055.1 - 0.36 11.4 30.8 0.05 14.1 4.4 3.8 3 1 1 4 4 4 0 Apg6 coiled-coil region Mto2_bdg PF12808.7 ORY46055.1 - 0.37 11.1 0.1 0.37 11.1 0.1 4.2 4 0 0 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region CENP-F_leu_zip PF10473.9 ORY46055.1 - 0.7 9.9 31.6 0.096 12.7 10.2 4.5 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TSC22 PF01166.18 ORY46055.1 - 0.91 9.9 5.3 13 6.2 0.1 4.0 4 0 0 4 4 4 0 TSC-22/dip/bun family DUF1664 PF07889.12 ORY46055.1 - 0.93 9.5 19.8 13 5.9 1.4 4.1 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) FtsH_ext PF06480.15 ORY46055.1 - 2 8.8 8.6 44 4.5 3.9 3.5 2 1 0 2 2 2 0 FtsH Extracellular Filament PF00038.21 ORY46055.1 - 4.3 6.8 29.5 11 5.5 4.8 3.7 2 2 0 2 2 2 0 Intermediate filament protein UPF0242 PF06785.11 ORY46055.1 - 6.8 6.7 22.0 2.6 8.1 1.3 3.4 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus WD40 PF00400.32 ORY46057.1 - 1.2e-45 152.6 19.8 1.9e-07 31.6 0.0 9.2 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY46057.1 - 2.3e-16 59.9 2.9 0.00047 20.4 0.1 6.1 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain TIR_2 PF13676.6 ORY46057.1 - 4.3e-15 56.4 0.0 9.9e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 TIR domain Nup160 PF11715.8 ORY46057.1 - 1.1e-13 50.7 5.3 0.0014 17.3 0.0 5.9 2 2 2 6 6 6 5 Nucleoporin Nup120/160 NACHT PF05729.12 ORY46057.1 - 7.2e-10 39.0 0.0 2.4e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 NACHT domain Ge1_WD40 PF16529.5 ORY46057.1 - 7.6e-06 25.1 7.4 0.92 8.4 0.0 5.0 2 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ORY46057.1 - 0.00034 20.0 0.1 0.014 14.8 0.1 2.7 2 0 0 2 2 2 1 WD40-like domain AAA_16 PF13191.6 ORY46057.1 - 0.0011 19.4 0.0 0.0023 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Cytochrom_D1 PF02239.16 ORY46057.1 - 0.013 14.0 0.0 0.034 12.7 0.0 1.6 1 1 0 1 1 1 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 ORY46057.1 - 0.019 13.8 5.8 0.35 9.6 1.3 3.4 2 2 0 2 2 2 0 Nup133 N terminal like TIR PF01582.20 ORY46057.1 - 0.08 12.7 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 TIR domain DUF2075 PF09848.9 ORY46057.1 - 0.081 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 ORY46057.1 - 0.12 11.8 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region RasGEF PF00617.19 ORY46058.1 - 4e-11 43.4 0.2 7e-11 42.7 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY46058.1 - 4e-06 27.0 0.8 0.00057 20.1 0.2 2.6 1 1 1 2 2 2 2 RasGEF N-terminal motif DUF2318 PF10080.9 ORY46058.1 - 0.084 13.0 0.6 0.16 12.1 0.6 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) GSG-1 PF07803.11 ORY46058.1 - 1.9 8.5 4.4 4.3 7.3 4.4 1.7 1 1 0 1 1 1 0 GSG1-like protein DUF4588 PF15251.6 ORY46059.1 - 0.00055 19.8 0.2 0.00055 19.8 0.2 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4588) CheY-binding PF09078.11 ORY46059.1 - 0.024 14.7 0.1 0.094 12.8 0.0 2.1 2 0 0 2 2 2 0 CheY binding WD40 PF00400.32 ORY46060.1 - 1.9e-57 189.9 36.0 3.7e-09 37.0 1.2 9.4 8 1 1 9 9 9 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY46060.1 - 6.3e-23 80.9 10.7 2.8e-05 24.3 0.0 7.0 2 1 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY46060.1 - 2.8e-10 39.5 13.3 0.031 12.9 0.2 7.7 1 1 8 9 9 9 5 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY46060.1 - 1.4e-07 31.2 0.8 0.023 14.0 0.0 3.3 1 1 2 3 3 3 3 WD40-like domain Ge1_WD40 PF16529.5 ORY46060.1 - 4.5e-07 29.1 5.9 2.3 7.1 0.0 6.1 2 1 5 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORY46060.1 - 0.00042 19.0 0.4 0.12 10.8 0.1 2.7 1 1 1 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 ORY46060.1 - 0.022 13.5 0.9 6.3 5.4 0.1 3.2 2 1 1 3 3 3 0 Nup133 N terminal like Coatomer_WDAD PF04053.14 ORY46060.1 - 0.034 13.2 0.4 4.6 6.2 0.2 2.4 2 1 0 2 2 2 0 Coatomer WD associated region FeThRed_A PF02941.15 ORY46060.1 - 0.096 12.8 0.2 3.5 7.8 0.1 3.1 3 0 0 3 3 3 0 Ferredoxin thioredoxin reductase variable alpha chain DUF1513 PF07433.11 ORY46060.1 - 0.1 11.7 9.3 3.8 6.5 0.5 4.6 2 2 2 4 4 4 0 Protein of unknown function (DUF1513) Kelch_2 PF07646.15 ORY46060.1 - 0.16 12.0 12.1 0.42 10.7 0.1 5.1 6 0 0 6 6 6 0 Kelch motif FliG_N PF14842.6 ORY46061.1 - 0.06 13.9 0.0 0.13 12.9 0.0 1.5 2 0 0 2 2 2 0 FliG N-terminal domain TIR_2 PF13676.6 ORY46062.1 - 1.8e-17 64.0 0.0 4.1e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 TIR domain NACHT PF05729.12 ORY46062.1 - 1.5e-07 31.5 0.1 6.8e-07 29.4 0.1 1.9 1 1 0 1 1 1 1 NACHT domain TIR PF01582.20 ORY46062.1 - 6.2e-06 26.1 0.1 1.1e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 TIR domain AAA_16 PF13191.6 ORY46062.1 - 0.00091 19.6 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain DUF1863 PF08937.11 ORY46062.1 - 0.0012 19.1 0.7 0.0081 16.5 0.1 2.6 2 1 0 2 2 2 1 MTH538 TIR-like domain (DUF1863) DUF1488 PF07369.11 ORY46062.1 - 0.0022 17.9 0.0 0.0049 16.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1488) DUF2075 PF09848.9 ORY46062.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 ORY46062.1 - 0.047 13.2 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Aha1_N PF09229.11 ORY46063.1 - 6.3e-36 123.6 0.7 9.6e-36 123.0 0.7 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 ORY46063.1 - 9.1e-08 32.4 0.1 8e-07 29.3 0.0 2.5 2 1 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein DUF3868 PF12984.7 ORY46063.1 - 0.076 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3868) TolA_bind_tri PF16331.5 ORY46064.1 - 0.00059 19.9 6.1 0.00059 19.9 6.1 6.5 4 1 2 6 6 6 1 TolA binding protein trimerisation ZirS_C PF16583.5 ORY46064.1 - 0.091 12.3 0.0 0.46 10.1 0.0 2.2 2 1 0 2 2 2 0 Zinc-regulated secreted antivirulence protein C-terminal domain Tis11B_N PF04553.12 ORY46064.1 - 1.2 9.8 5.7 0.45 11.1 0.3 2.9 2 1 0 2 2 2 0 Tis11B like protein, N terminus VWA_2 PF13519.6 ORY46065.1 - 3.2e-25 88.8 0.0 1.5e-24 86.7 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 ORY46065.1 - 1.4e-09 38.1 0.0 1.6e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.28 ORY46065.1 - 2.3e-09 37.8 0.1 3.2e-09 37.3 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Kinesin PF00225.23 ORY46066.1 - 3.7e-58 197.0 2.2 3.7e-58 197.0 2.2 3.3 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ORY46066.1 - 6.2e-30 104.1 0.0 2.1e-29 102.4 0.0 2.0 1 1 0 1 1 1 1 Microtubule binding Filament PF00038.21 ORY46066.1 - 3.6e-06 26.8 13.7 5.7e-06 26.1 13.7 1.2 1 0 0 1 1 1 1 Intermediate filament protein ADIP PF11559.8 ORY46066.1 - 0.0002 21.5 7.4 0.0002 21.5 7.4 3.1 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding HAP1_N PF04849.13 ORY46066.1 - 0.029 13.6 17.1 0.043 13.0 17.1 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region UPF0242 PF06785.11 ORY46066.1 - 0.085 12.9 20.6 0.97 9.5 20.5 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CHASE2 PF05226.11 ORY46066.1 - 0.096 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 CHASE2 domain NPV_P10 PF05531.12 ORY46066.1 - 0.25 11.8 4.3 0.13 12.7 1.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.10 ORY46066.1 - 1 9.5 11.4 1.9 8.7 10.6 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 ORY46066.1 - 1.3 9.7 9.5 0.081 13.6 1.5 2.8 2 1 0 2 2 2 0 SlyX DUF4201 PF13870.6 ORY46066.1 - 1.7 8.3 21.0 1.7 8.3 16.2 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) HIP1_clath_bdg PF16515.5 ORY46066.1 - 1.9 9.2 23.3 4.7 7.9 2.5 3.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 ORY46066.1 - 3.1 6.6 26.5 6.7 5.5 23.2 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Cortex-I_coil PF09304.10 ORY46066.1 - 4.3 7.6 20.0 4.9 7.4 7.0 3.0 2 0 0 2 2 2 0 Cortexillin I, coiled coil Atg14 PF10186.9 ORY46066.1 - 5.7 5.9 23.1 0.47 9.5 15.4 2.3 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 V_ATPase_I PF01496.19 ORY46066.1 - 7.5 4.3 10.9 12 3.7 10.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rho_Binding PF08912.11 ORY46066.1 - 8.4 7.3 23.3 6.8 7.6 9.9 4.3 2 1 3 5 5 5 0 Rho Binding DUF641 PF04859.12 ORY46066.1 - 9.9 6.5 17.8 0.52 10.6 3.4 3.3 2 1 1 3 3 3 0 Plant protein of unknown function (DUF641) EF-hand_9 PF14658.6 ORY46067.1 - 0.097 13.0 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain PilX_N PF14341.6 ORY46067.1 - 0.11 12.4 0.1 0.3 11.1 0.1 1.7 1 0 0 1 1 1 0 PilX N-terminal SH3_9 PF14604.6 ORY46068.1 - 4.9e-39 132.0 1.0 1.3e-10 40.9 0.0 4.2 4 0 0 4 4 4 4 Variant SH3 domain SH3_1 PF00018.28 ORY46068.1 - 1.1e-34 117.8 2.2 1.4e-09 37.4 0.1 4.2 4 0 0 4 4 4 4 SH3 domain SH3_2 PF07653.17 ORY46068.1 - 1.6e-22 78.9 0.7 3.8e-06 26.5 0.0 4.3 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.11 ORY46068.1 - 0.11 12.8 3.4 13 6.1 0.1 3.2 3 0 0 3 3 3 0 Bacterial SH3 domain SH3_9 PF14604.6 ORY46069.1 - 1.2e-14 53.9 0.1 1.6e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY46069.1 - 7.1e-12 44.7 0.0 9.2e-12 44.4 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY46069.1 - 4.1e-06 26.4 0.0 5.5e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain LPD16 PF18830.1 ORY46069.1 - 0.018 14.9 0.1 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 16 LRR_8 PF13855.6 ORY46072.1 - 7.4e-35 118.5 40.8 1.6e-11 43.8 0.9 6.4 2 2 3 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 ORY46072.1 - 8.1e-18 64.2 54.8 0.00011 22.6 2.1 8.2 2 1 11 13 13 13 12 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY46072.1 - 1.2e-08 34.4 43.9 0.19 12.4 1.2 11.5 12 0 0 12 12 12 5 Leucine Rich Repeat F-box PF00646.33 ORY46072.1 - 6.2e-05 22.8 0.3 0.00018 21.3 0.3 1.9 1 0 0 1 1 1 1 F-box domain TRF PF08558.10 ORY46072.1 - 0.048 13.3 0.9 0.083 12.5 0.9 1.4 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) LRR_9 PF14580.6 ORY46072.1 - 0.061 12.8 11.8 0.56 9.7 0.8 3.5 1 1 3 4 4 4 0 Leucine-rich repeat Sec34 PF04136.15 ORY46072.1 - 4.2 7.2 6.4 0.72 9.7 2.0 1.9 2 0 0 2 2 2 0 Sec34-like family Vps52 PF04129.12 ORY46073.1 - 7.2e-133 444.0 8.3 1.1e-80 271.9 2.4 2.0 2 0 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.9 ORY46073.1 - 5.2e-07 28.5 4.3 5.2e-07 28.5 4.3 2.2 2 0 0 2 2 2 2 Exocyst complex component Sec3 DUF4811 PF16069.5 ORY46073.1 - 0.063 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4811) LRR_4 PF12799.7 ORY46074.1 - 1.1e-09 38.4 8.8 7.4e-06 26.2 1.4 2.9 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY46074.1 - 1.6e-08 34.2 6.2 9.7e-06 25.3 1.0 2.5 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 ORY46074.1 - 5.6e-06 26.2 3.0 0.72 10.6 0.1 4.5 4 0 0 4 4 4 2 Leucine Rich Repeat DGF-1_5 PF11038.8 ORY46074.1 - 0.0096 15.3 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Dispersed gene family protein 1 of Trypanosoma cruzi region 5 LRR_6 PF13516.6 ORY46074.1 - 0.011 15.7 7.9 1.4 9.2 0.3 3.8 4 0 0 4 4 4 0 Leucine Rich repeat DUF445 PF04286.12 ORY46075.1 - 0.1 12.4 7.0 0.11 12.2 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) SecA_SW PF07516.13 ORY46075.1 - 0.47 10.5 8.8 0.53 10.3 8.2 1.3 1 1 0 1 1 1 0 SecA Wing and Scaffold domain PELOTA_1 PF15608.6 ORY46077.1 - 0.043 13.7 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain B2-adapt-app_C PF09066.10 ORY46078.1 - 2e-16 60.1 1.2 5e-16 58.8 1.2 1.7 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain Alpha_adaptinC2 PF02883.20 ORY46078.1 - 5.4e-05 23.5 1.0 8.6e-05 22.8 0.1 1.8 2 0 0 2 2 2 1 Adaptin C-terminal domain Adaptin_N PF01602.20 ORY46079.1 - 4.8e-130 434.6 11.2 5.7e-130 434.3 11.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ORY46079.1 - 6.6e-54 182.3 7.9 1.3e-52 178.1 1.6 3.1 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORY46079.1 - 2e-12 47.3 4.7 0.00083 19.7 0.3 5.1 3 2 3 7 7 7 3 HEAT repeats HEAT PF02985.22 ORY46079.1 - 9.7e-06 25.4 7.4 0.22 11.9 0.1 5.8 7 0 0 7 7 7 2 HEAT repeat Arm PF00514.23 ORY46079.1 - 8.3e-05 22.5 1.5 0.0018 18.3 0.1 3.7 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 ORY46079.1 - 0.00026 21.2 5.9 0.27 11.4 0.2 5.0 3 2 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 ORY46079.1 - 0.0012 19.3 2.2 0.54 10.8 0.1 3.7 2 1 1 3 3 3 1 HEAT-like repeat Cnd3 PF12719.7 ORY46079.1 - 0.004 16.4 0.3 0.015 14.5 0.1 2.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 ORY46079.1 - 0.016 14.8 1.3 4.6 6.7 0.1 3.0 2 2 0 2 2 2 0 CLASP N terminal V-ATPase_H_C PF11698.8 ORY46079.1 - 0.15 12.2 7.2 0.44 10.7 0.8 3.9 3 2 0 4 4 4 0 V-ATPase subunit H Acyl-CoA_dh_1 PF00441.24 ORY46080.1 - 3.2e-24 85.8 0.3 4.9e-24 85.2 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY46080.1 - 1.2e-20 73.5 0.0 2.5e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORY46080.1 - 9.4e-20 71.4 0.6 2e-19 70.3 0.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY46080.1 - 4.8e-09 36.6 0.2 7.6e-09 36.0 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 ORY46080.1 - 0.017 14.8 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 0 4-hydroxyphenylacetate 3-hydroxylase N terminal RIBIOP_C PF04950.12 ORY46082.1 - 2.6e-96 322.5 0.1 2.6e-96 322.5 0.1 1.6 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 ORY46082.1 - 5.6e-32 109.7 0.0 2.1e-31 107.9 0.0 2.1 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA PF00004.29 ORY46082.1 - 4.9e-06 27.0 0.0 1.5e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY46082.1 - 3.3e-05 24.2 0.0 0.00012 22.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY46082.1 - 9.4e-05 22.6 0.0 0.00029 21.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY46082.1 - 0.00015 22.2 0.0 0.00049 20.5 0.0 1.8 2 0 0 2 2 1 1 AAA ATPase domain AAA_18 PF13238.6 ORY46082.1 - 0.0014 19.2 3.9 0.002 18.7 0.0 3.2 3 1 0 3 3 2 1 AAA domain ABC_tran PF00005.27 ORY46082.1 - 0.002 18.6 0.4 0.0084 16.6 0.0 2.3 2 0 0 2 2 1 1 ABC transporter AAA_28 PF13521.6 ORY46082.1 - 0.0021 18.3 0.2 0.0072 16.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 ORY46082.1 - 0.0035 17.1 0.0 0.0075 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY46082.1 - 0.0045 17.3 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 ORY46082.1 - 0.0047 16.9 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain MMR_HSR1 PF01926.23 ORY46082.1 - 0.0048 17.0 0.0 0.017 15.2 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 ORY46082.1 - 0.0074 16.7 0.0 0.024 15.0 0.0 1.9 1 0 0 1 1 1 1 RNA helicase cobW PF02492.19 ORY46082.1 - 0.0076 15.8 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 ORY46082.1 - 0.01 15.1 0.5 0.18 11.1 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.14 ORY46082.1 - 0.02 14.9 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 ORY46082.1 - 0.026 14.3 0.2 0.026 14.3 0.2 3.6 3 1 0 3 3 3 0 AAA domain AAA_14 PF13173.6 ORY46082.1 - 0.034 14.2 0.5 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORY46082.1 - 0.035 13.6 0.1 0.085 12.4 0.0 1.6 2 0 0 2 2 1 0 P-loop containing dynein motor region NTPase_1 PF03266.15 ORY46082.1 - 0.037 13.9 0.2 0.08 12.9 0.2 1.5 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 ORY46082.1 - 0.043 13.0 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Viral_helicase1 PF01443.18 ORY46082.1 - 0.046 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 ORY46082.1 - 0.05 13.5 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.6 ORY46082.1 - 0.062 12.9 0.0 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY46082.1 - 0.077 12.7 0.1 0.077 12.7 0.1 2.3 3 0 0 3 3 3 0 AAA domain MobB PF03205.14 ORY46082.1 - 0.077 12.9 0.7 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B U1snRNP70_N PF12220.8 ORY46082.1 - 0.43 11.3 11.4 4.3 8.1 0.5 4.0 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Haemadin PF09065.10 ORY46083.1 - 0.035 13.9 2.6 0.035 13.9 2.6 2.5 4 0 0 4 4 4 0 Haemadin PFK PF00365.20 ORY46084.1 - 2e-145 483.5 0.0 6.9e-88 294.7 0.0 3.4 2 2 1 3 3 3 3 Phosphofructokinase ubiquitin PF00240.23 ORY46086.1 - 4.3e-35 119.3 0.5 7e-35 118.6 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY46086.1 - 1.6e-16 59.9 0.6 1.6e-16 59.9 0.6 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORY46086.1 - 5.7e-06 26.7 0.1 2.7e-05 24.5 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORY46086.1 - 0.00017 21.7 0.9 0.00035 20.7 0.9 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 ORY46086.1 - 0.0026 18.1 1.1 0.0038 17.6 0.1 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain Ubiquitin_4 PF18036.1 ORY46086.1 - 0.003 17.6 0.7 1.9 8.6 0.1 2.4 2 0 0 2 2 2 2 Ubiquitin-like domain DUF2407 PF10302.9 ORY46086.1 - 0.0031 18.0 0.9 0.0039 17.7 0.9 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain TBK1_ULD PF18396.1 ORY46086.1 - 0.0033 17.3 0.0 0.0043 17.0 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Sde2_N_Ubi PF13019.6 ORY46086.1 - 0.038 13.8 0.0 0.057 13.3 0.0 1.3 1 1 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain TPR_2 PF07719.17 ORY46087.1 - 1.8e-06 27.6 0.2 0.0039 17.2 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY46087.1 - 4.1e-06 26.4 0.2 0.0091 15.8 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY46087.1 - 7.6e-06 26.4 0.0 8.5e-06 26.2 0.0 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY46087.1 - 7.2e-05 22.4 0.0 8.9e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 TPR repeat TPR_17 PF13431.6 ORY46087.1 - 0.00011 22.3 0.0 0.00025 21.2 0.0 1.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY46087.1 - 0.0022 17.9 0.1 0.014 15.3 0.0 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY46087.1 - 0.0043 17.3 0.1 0.027 14.7 0.1 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY46087.1 - 0.0093 16.7 0.0 0.013 16.2 0.0 1.3 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY46087.1 - 0.0096 16.6 0.0 0.011 16.3 0.0 1.1 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY46087.1 - 0.01 16.4 0.1 6.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat F-box-like PF12937.7 ORY46089.1 - 3.4e-05 23.7 0.6 6.9e-05 22.7 0.6 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY46089.1 - 0.023 14.6 0.1 0.049 13.5 0.1 1.5 1 0 0 1 1 1 0 F-box domain DUF1951 PF09188.10 ORY46090.1 - 0.13 12.2 0.2 0.24 11.4 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1951) Snf7 PF03357.21 ORY46092.1 - 8.4e-37 126.4 8.5 1.1e-36 126.0 8.5 1.2 1 0 0 1 1 1 1 Snf7 CCDC24 PF15669.5 ORY46092.1 - 0.02 14.7 0.2 0.02 14.7 0.2 1.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Ribosomal_60s PF00428.19 ORY46092.1 - 0.042 14.4 2.2 0.14 12.7 0.2 2.2 1 1 1 2 2 2 0 60s Acidic ribosomal protein p450 PF00067.22 ORY46093.1 - 3.6e-78 263.4 0.0 4e-78 263.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ORY46094.1 - 1.3e-82 278.0 0.4 1.6e-82 277.7 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 Curto_V3 PF07436.11 ORY46094.1 - 0.15 12.5 0.1 0.37 11.2 0.1 1.6 1 0 0 1 1 1 0 Curtovirus V3 protein Transket_pyr PF02779.24 ORY46095.1 - 1.5e-37 129.0 0.0 2.2e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORY46095.1 - 2e-34 118.1 0.0 4.1e-34 117.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Glyco_tran_WecB PF03808.13 ORY46095.1 - 0.038 13.9 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Peptidase_S10 PF00450.22 ORY46096.1 - 3.9e-78 263.7 0.2 4.8e-78 263.4 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase VHS PF00790.19 ORY46097.1 - 3.8e-06 26.8 0.0 5.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 VHS domain IcmF_C PF06744.12 ORY46098.1 - 0.0017 18.0 0.1 0.002 17.8 0.1 1.1 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal VHS PF00790.19 ORY46098.1 - 0.035 14.0 0.1 0.049 13.5 0.1 1.4 1 0 0 1 1 1 0 VHS domain Histone_H2A_C PF16211.5 ORY46099.1 - 3.1e-19 68.4 0.7 7.3e-19 67.2 0.7 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 ORY46099.1 - 5.4e-16 59.1 0.0 7e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY46099.1 - 3.7e-05 23.9 0.0 4.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LRR_8 PF13855.6 ORY46100.1 - 6.3e-14 51.5 18.7 2.3e-06 27.2 0.7 3.3 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY46100.1 - 3.8e-08 33.5 24.1 0.0012 19.2 1.7 4.8 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY46100.1 - 7.4e-05 22.8 26.4 2.7 8.9 0.1 7.6 8 0 0 8 8 8 4 Leucine Rich Repeat F-box PF00646.33 ORY46100.1 - 0.0018 18.1 0.2 0.0058 16.5 0.2 1.9 1 0 0 1 1 1 1 F-box domain ZT_dimer PF16916.5 ORY46101.1 - 2.4e-11 43.6 0.2 3.8e-11 43.0 0.2 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Cation_efflux PF01545.21 ORY46101.1 - 1.5e-08 34.6 5.6 2.5e-08 33.9 5.6 1.3 1 0 0 1 1 1 1 Cation efflux family IcmF_C PF06744.12 ORY46102.1 - 0.0055 16.3 0.1 0.0065 16.1 0.1 1.2 1 0 0 1 1 1 1 Type VI secretion protein IcmF C-terminal VHS PF00790.19 ORY46102.1 - 0.028 14.3 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 VHS domain Histone_H2A_C PF16211.5 ORY46103.1 - 1e-19 69.9 0.7 1.7e-19 69.2 0.7 1.3 1 0 0 1 1 1 1 C-terminus of histone H2A Ribosomal_S24e PF01282.19 ORY46104.1 - 0.032 14.2 0.0 0.04 13.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S24e Exo_endo_phos_2 PF14529.6 ORY46105.1 - 0.0062 16.4 0.5 0.011 15.6 0.1 1.6 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-CCHC PF00098.23 ORY46106.1 - 4.7e-07 29.6 2.1 7.6e-07 28.9 2.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 ORY46106.1 - 0.015 15.0 0.6 0.038 13.7 0.6 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 ORY46106.1 - 0.15 11.8 0.5 0.46 10.3 0.5 1.8 1 0 0 1 1 1 0 Zinc knuckle MeaB PF03308.16 ORY46107.1 - 0.33 9.9 1.0 0.51 9.3 0.6 1.4 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB YABBY PF04690.13 ORY46107.1 - 0.56 10.7 3.3 0.45 11.1 0.6 2.0 2 0 0 2 2 2 0 YABBY protein Ribosomal_S24e PF01282.19 ORY46110.1 - 0.032 14.2 0.0 0.04 13.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein S24e LRR_8 PF13855.6 ORY46111.1 - 2e-16 59.5 19.5 1.8e-05 24.4 2.4 3.8 2 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 ORY46111.1 - 8e-14 51.5 18.1 8.4e-05 22.9 0.0 4.5 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY46111.1 - 1.2e-07 31.3 22.0 3.5 8.5 0.0 7.3 8 0 0 8 8 8 4 Leucine Rich Repeat LRR_6 PF13516.6 ORY46111.1 - 0.0027 17.6 17.2 0.62 10.3 0.1 5.7 6 0 0 6 6 6 2 Leucine Rich repeat HILPDA PF15220.6 ORY46112.1 - 0.39 10.9 1.1 0.73 10.0 1.1 1.5 1 1 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated Gal-bind_lectin PF00337.22 ORY46113.1 - 0.45 10.1 2.2 6.5 6.3 2.2 2.1 1 1 0 1 1 1 0 Galactoside-binding lectin FlaC_arch PF05377.11 ORY46114.1 - 1.8e-05 25.0 5.3 0.61 10.5 0.0 3.7 3 0 0 3 3 3 3 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 ORY46114.1 - 0.0083 16.2 8.3 0.0089 16.1 3.5 2.5 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.11 ORY46114.1 - 0.12 11.3 6.9 0.27 10.1 1.2 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein KxDL PF10241.9 ORY46114.1 - 0.21 11.9 3.0 2.7 8.3 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein HTH_Tnp_IS630 PF01710.16 ORY46114.1 - 0.54 10.3 2.8 0.43 10.6 0.5 2.0 2 0 0 2 2 2 0 Transposase Golgin_A5 PF09787.9 ORY46114.1 - 0.64 9.4 9.4 8.1 5.8 0.2 2.8 2 1 1 3 3 3 0 Golgin subfamily A member 5 RP-C_C PF11800.8 ORY46114.1 - 9.7 6.2 10.3 2.4 8.2 0.3 3.1 2 1 1 3 3 3 0 Replication protein C C-terminal region HMG_box PF00505.19 ORY46118.1 - 3.6e-17 62.5 10.8 2.3e-08 34.4 0.1 4.0 3 1 0 3 3 3 3 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY46118.1 - 2e-13 50.7 8.0 1.4e-06 28.8 6.2 3.3 2 1 0 2 2 2 2 HMG-box domain Protamine_like PF06382.11 ORY46118.1 - 0.06 13.5 1.0 0.2 11.8 0.4 2.0 1 1 1 2 2 2 0 Protamine and protamine like SSB PF00436.25 ORY46119.1 - 1.5e-07 31.4 0.0 2.3e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Single-strand binding protein family HMG_box PF00505.19 ORY46120.1 - 1.6e-07 31.6 0.1 3.4e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY46120.1 - 2.6e-05 24.7 1.6 3.7e-05 24.2 0.1 2.0 2 1 1 3 3 3 1 HMG-box domain CA_like PF10563.9 ORY46120.1 - 0.072 13.0 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Putative carbonic anhydrase Glyco_transf_22 PF03901.17 ORY46121.1 - 2.1e-81 274.3 23.7 2.5e-81 274.0 23.7 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family LRR_8 PF13855.6 ORY46122.1 - 7e-14 51.3 4.4 3.6e-08 33.1 2.8 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY46122.1 - 4.8e-12 45.9 6.4 2.8e-05 24.4 0.3 2.8 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY46122.1 - 3.4e-06 26.8 4.3 2.8 8.8 0.1 5.3 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 ORY46122.1 - 0.0029 17.5 13.2 0.65 10.2 0.2 4.8 5 0 0 5 5 5 3 Leucine Rich repeat PP2C PF00481.21 ORY46123.1 - 1.9e-76 257.1 0.0 2.8e-76 256.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C TPM_phosphatase PF04536.14 ORY46123.1 - 0.071 13.3 0.1 0.19 11.9 0.0 1.6 2 0 0 2 2 2 0 TPM domain LRR_8 PF13855.6 ORY46124.1 - 1.6e-11 43.8 20.5 1.3e-06 28.0 4.1 3.2 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY46124.1 - 1.7e-07 31.5 11.8 0.00057 20.2 0.9 3.3 1 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY46124.1 - 0.37 11.5 14.8 4 8.4 0.2 4.7 5 0 0 5 5 5 0 Leucine Rich Repeat Lzipper-MIP1 PF14389.6 ORY46125.1 - 0.1 12.9 7.3 0.49 10.7 1.1 3.3 3 1 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 JIP_LZII PF16471.5 ORY46125.1 - 0.2 11.9 3.9 0.15 12.2 1.0 2.4 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II DivIVA PF05103.13 ORY46125.1 - 0.25 11.4 10.9 0.16 12.1 0.3 3.0 3 0 0 3 3 3 0 DivIVA protein V_ATPase_I PF01496.19 ORY46125.1 - 0.4 8.6 5.6 0.48 8.3 5.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.12 ORY46125.1 - 1.5 8.8 9.2 9.5 6.3 1.8 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) LSM PF01423.22 ORY46126.1 - 3.7e-21 74.6 0.1 4.2e-21 74.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 ORY46126.1 - 0.0074 16.4 0.0 0.011 15.8 0.0 1.3 1 1 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 ORY46126.1 - 0.028 14.6 0.0 0.033 14.3 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain zf-CCHC PF00098.23 ORY46127.1 - 3.9e-14 52.0 22.7 0.00093 19.2 3.0 4.2 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.6 ORY46127.1 - 6.7e-06 25.8 17.7 0.00023 20.9 1.5 4.0 4 0 0 4 4 4 2 Zinc knuckle zf-CCHC_4 PF14392.6 ORY46127.1 - 1.7e-05 24.5 14.8 0.081 12.7 0.2 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_5 PF14787.6 ORY46127.1 - 0.019 14.7 0.4 0.019 14.7 0.4 3.8 4 0 0 4 4 4 0 GAG-polyprotein viral zinc-finger PHD_4 PF16866.5 ORY46127.1 - 7.7 6.7 16.3 5.4 7.2 2.4 3.6 2 1 3 5 5 5 0 PHD-finger Porin_3 PF01459.22 ORY46128.1 - 2.2e-63 214.3 6.7 2.5e-63 214.1 6.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF4097 PF13349.6 ORY46129.1 - 0.00029 20.3 0.0 0.0006 19.2 0.0 1.7 1 1 0 1 1 1 1 Putative adhesin Sporozoite_P67 PF05642.11 ORY46130.1 - 1.1 7.3 6.0 1.4 6.9 6.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Med3 PF11593.8 ORY46130.1 - 5.5 6.1 16.9 6.9 5.7 0.0 2.3 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF1269 PF06897.12 ORY46131.1 - 0.025 14.8 0.9 0.08 13.2 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) DUF3335 PF11814.8 ORY46131.1 - 0.039 13.4 0.0 0.086 12.3 0.0 1.5 1 0 0 1 1 1 0 Peptidase_C39 like family DnaJ PF00226.31 ORY46131.1 - 0.084 13.0 1.3 0.36 11.0 0.1 2.5 3 0 0 3 3 3 0 DnaJ domain SWIM PF04434.17 ORY46131.1 - 0.19 11.4 0.1 0.57 9.9 0.1 1.8 2 0 0 2 2 2 0 SWIM zinc finger Bacteriocin_IIc PF10439.9 ORY46131.1 - 3.9 7.7 11.9 6.5 7.0 11.9 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF4097 PF13349.6 ORY46134.1 - 1.8e-09 37.4 0.2 3.5e-09 36.4 0.2 1.6 1 1 0 1 1 1 1 Putative adhesin UAA PF08449.11 ORY46135.1 - 1.6e-10 40.7 12.1 3.1e-10 39.8 12.1 1.4 1 0 0 1 1 1 1 UAA transporter family DUF4097 PF13349.6 ORY46138.1 - 1.1e-05 25.0 1.9 1.6e-05 24.4 1.9 1.3 1 0 0 1 1 1 1 Putative adhesin SprB PF13573.6 ORY46138.1 - 5.4 6.9 6.1 4.9 7.0 0.1 3.6 3 1 1 4 4 4 0 SprB repeat PLA2G12 PF06951.11 ORY46139.1 - 0.031 14.2 3.1 0.051 13.5 3.1 1.4 1 0 0 1 1 1 0 Group XII secretory phospholipase A2 precursor (PLA2G12) Phospholip_A2_3 PF09056.11 ORY46139.1 - 0.034 14.8 0.4 0.034 14.8 0.4 2.5 1 1 1 2 2 2 0 Prokaryotic phospholipase A2 DUF456 PF04306.13 ORY46140.1 - 0.00082 19.7 0.4 0.0013 19.0 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF456) DnaJ PF00226.31 ORY46140.1 - 0.0022 18.1 2.0 0.024 14.7 0.7 2.6 2 1 0 2 2 2 1 DnaJ domain DUF1269 PF06897.12 ORY46140.1 - 0.0082 16.4 1.6 0.018 15.3 1.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1269) Gly-zipper_Omp PF13488.6 ORY46140.1 - 0.4 10.7 10.5 0.62 10.1 10.5 1.3 1 0 0 1 1 1 0 Glycine zipper Rick_17kDa_Anti PF05433.15 ORY46140.1 - 0.43 10.5 10.2 0.61 10.0 10.2 1.2 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF1269 PF06897.12 ORY46141.1 - 0.00041 20.6 1.8 0.00068 19.9 1.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1269) DUF456 PF04306.13 ORY46141.1 - 0.00068 19.9 2.5 0.0011 19.3 2.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.9 ORY46141.1 - 0.013 15.6 10.5 0.096 12.8 11.0 2.0 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.6 ORY46141.1 - 0.015 15.0 13.7 0.023 14.4 13.7 1.2 1 0 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 ORY46141.1 - 0.052 13.5 20.2 0.08 13.0 20.2 1.2 1 0 0 1 1 1 0 Glycine zipper Rick_17kDa_Anti PF05433.15 ORY46141.1 - 7.7 6.5 21.8 15 5.6 5.2 1.9 1 1 1 2 2 2 0 Glycine zipper 2TM domain CDP-OH_P_transf PF01066.21 ORY46142.1 - 1.1e-17 64.5 0.1 1.1e-17 64.5 0.1 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase TPR_12 PF13424.6 ORY46143.1 - 2.9e-07 30.7 5.5 0.024 14.9 0.0 3.3 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY46143.1 - 5.3e-05 23.0 7.4 0.04 14.0 0.1 4.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY46143.1 - 6.2e-05 22.6 2.8 0.056 13.3 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY46143.1 - 0.00024 21.0 4.5 0.13 12.5 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY46143.1 - 0.0014 18.5 1.7 2.4 8.4 0.0 4.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY46143.1 - 0.016 15.7 0.7 0.075 13.6 0.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat PDDEXK_10 PF07788.11 ORY46143.1 - 0.019 14.9 0.4 0.29 11.1 0.1 2.3 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily TPR_10 PF13374.6 ORY46143.1 - 0.072 13.0 5.4 2.8 7.9 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY46143.1 - 0.19 12.4 1.5 70 4.4 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Gln-synt_C PF00120.24 ORY46146.1 - 4.1e-59 200.3 0.2 9.3e-55 186.0 0.4 3.0 1 1 1 2 2 2 2 Glutamine synthetase, catalytic domain Ras PF00071.22 ORY46148.1 - 1e-45 155.3 1.0 5e-37 127.0 0.1 2.0 1 1 1 2 2 2 2 Ras family Roc PF08477.13 ORY46148.1 - 2.6e-28 98.7 0.2 3.6e-28 98.2 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY46148.1 - 4.5e-13 49.0 0.1 7.2e-13 48.4 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY46148.1 - 1.2e-06 28.5 0.0 2.3e-06 27.7 0.0 1.4 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORY46148.1 - 9.8e-06 25.1 0.0 1.6e-05 24.4 0.0 1.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORY46148.1 - 0.00018 21.1 0.3 0.0013 18.3 0.1 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 ORY46148.1 - 0.00031 20.2 0.0 0.00044 19.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 ORY46148.1 - 0.00098 19.7 0.0 0.0012 19.3 0.0 1.4 1 1 0 1 1 1 1 ABC transporter Septin PF00735.18 ORY46148.1 - 0.0041 16.4 0.0 0.006 15.9 0.0 1.2 1 0 0 1 1 1 1 Septin AAA_24 PF13479.6 ORY46148.1 - 0.0044 16.8 0.4 0.011 15.5 0.3 1.8 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY46148.1 - 0.0061 17.0 0.0 0.0081 16.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY46148.1 - 0.0067 16.7 0.0 0.022 15.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 ORY46148.1 - 0.0074 15.7 0.0 0.03 13.7 0.0 1.8 2 0 0 2 2 2 1 Bacterial TniB protein RsgA_GTPase PF03193.16 ORY46148.1 - 0.0075 16.2 0.0 0.052 13.5 0.0 2.0 1 1 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 ORY46148.1 - 0.013 15.3 0.1 0.028 14.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.18 ORY46148.1 - 0.037 13.6 0.0 0.5 9.9 0.0 2.1 1 1 1 2 2 2 0 Ferrous iron transport protein B gp45-slide_C PF09116.10 ORY46148.1 - 0.038 14.0 0.0 0.075 13.1 0.0 1.5 1 0 0 1 1 1 0 gp45 sliding clamp, C terminal AAA_5 PF07728.14 ORY46148.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) YwhD PF08741.10 ORY46148.1 - 0.11 12.2 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 YwhD family AAA_7 PF12775.7 ORY46148.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 ORY46148.1 - 0.13 12.0 0.9 0.78 9.5 0.0 2.5 2 1 1 3 3 3 0 Conserved hypothetical ATP binding protein MCM PF00493.23 ORY46148.1 - 0.14 11.3 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain DUF815 PF05673.13 ORY46148.1 - 0.14 11.3 0.0 0.33 10.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) G-alpha PF00503.20 ORY46148.1 - 0.15 11.2 1.5 3.3 6.8 0.2 2.1 1 1 1 2 2 2 0 G-protein alpha subunit DUF4097 PF13349.6 ORY46149.1 - 0.00068 19.1 0.4 0.00097 18.6 0.3 1.3 1 1 0 1 1 1 1 Putative adhesin zf_C2H2_ZHX PF18387.1 ORY46151.1 - 0.015 14.9 6.2 0.81 9.4 0.8 2.5 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain OrsD PF12013.8 ORY46151.1 - 0.068 13.6 6.5 0.28 11.6 1.6 2.8 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2 PF00096.26 ORY46151.1 - 0.51 10.9 9.1 6.1 7.5 0.0 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type BUD22 PF09073.10 ORY46152.1 - 1.9 7.8 11.8 2.3 7.5 11.8 1.1 1 0 0 1 1 1 0 BUD22 PNTB_4TM PF12769.7 ORY46154.1 - 3e-05 24.4 0.0 3.4 8.2 0.0 3.7 4 0 0 4 4 4 2 4TM region of pyridine nucleotide transhydrogenase, mitoch Cyd_oper_YbgE PF09600.10 ORY46154.1 - 0.13 12.7 1.5 64 4.0 0.0 3.7 4 0 0 4 4 4 0 Cyd operon protein YbgE (Cyd_oper_YbgE) HGTP_anticodon2 PF12745.7 ORY46155.1 - 0.05 13.1 0.2 0.064 12.8 0.2 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs AAA_19 PF13245.6 ORY46157.1 - 0.01 16.2 1.8 0.014 15.7 0.1 2.1 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 ORY46157.1 - 0.012 15.4 0.1 0.039 13.7 0.1 2.0 1 0 0 1 1 1 0 DEAD/DEAH box helicase ResIII PF04851.15 ORY46157.1 - 0.015 15.3 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 ORY46157.1 - 0.036 13.8 0.0 0.097 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 ORY46157.1 - 0.061 13.8 0.0 0.36 11.2 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoD PF09423.10 ORY46313.1 - 1.3e-83 280.9 1.2 1.6e-83 280.6 1.2 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 ORY46313.1 - 9.8e-08 32.4 0.1 5e-07 30.2 0.0 2.2 3 0 0 3 3 3 1 PhoD-like phosphatase, N-terminal domain Metallophos PF00149.28 ORY46313.1 - 0.15 12.5 2.2 1.8 9.0 2.2 2.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase Piwi PF02171.17 ORY46314.1 - 8.9e-29 100.7 0.0 1.3e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Piwi domain KDZ PF18758.1 ORY46317.1 - 6.3e-11 42.3 0.0 2.9e-10 40.1 0.0 2.0 1 1 1 2 2 2 1 Kyakuja-Dileera-Zisupton transposase YscO-like PF16789.5 ORY46318.1 - 0.014 15.4 2.7 0.62 10.1 0.3 2.5 2 0 0 2 2 2 0 YscO-like protein CdiI_3 PF18616.1 ORY46319.1 - 0.2 11.6 1.1 0.41 10.5 0.2 2.0 2 0 0 2 2 2 0 CDI immunity proteins DUF5564 PF17719.1 ORY46320.1 - 0.048 13.8 0.3 1.7 8.9 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5564) SMC_hinge PF06470.13 ORY46320.1 - 0.092 13.1 0.8 0.33 11.3 0.2 2.3 2 1 0 2 2 2 0 SMC proteins Flexible Hinge Domain Piwi PF02171.17 ORY46321.1 - 1e-11 44.7 0.2 2e-10 40.4 0.2 2.2 1 1 0 1 1 1 1 Piwi domain ArgoMid PF16487.5 ORY46321.1 - 0.00092 19.4 0.0 0.0071 16.6 0.0 2.5 2 0 0 2 2 2 1 Mid domain of argonaute ArgoN PF16486.5 ORY46321.1 - 0.003 18.2 0.1 0.0081 16.8 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 ORY46321.1 - 0.017 15.5 0.2 0.096 13.0 0.1 2.2 2 0 0 2 2 2 0 Argonaute linker 2 domain PhoD_N PF16655.5 ORY46322.1 - 1.2e-18 67.4 0.0 3.6e-18 65.9 0.0 1.8 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain PhoD PF09423.10 ORY46322.1 - 7.9e-08 31.7 0.4 1.1e-07 31.2 0.4 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase Pur_ac_phosph_N PF16656.5 ORY46322.1 - 0.0068 17.0 0.1 0.017 15.7 0.0 1.8 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain CagZ PF09053.10 ORY46322.1 - 0.099 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 CagZ RRM_1 PF00076.22 ORY46325.1 - 1.3e-27 95.4 0.1 7.5e-19 67.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY46325.1 - 0.0011 18.5 0.0 0.59 9.7 0.0 2.1 1 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORY46325.1 - 0.0065 16.5 0.5 0.6 10.2 0.0 2.3 2 1 0 2 2 2 1 RNA binding motif RRM_occluded PF16842.5 ORY46325.1 - 0.02 14.7 0.0 4 7.4 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF1866 PF08952.11 ORY46325.1 - 0.045 13.6 0.0 0.74 9.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1866) FoP_duplication PF13865.6 ORY46325.1 - 2 9.0 13.7 3.9 8.1 13.7 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.22 ORY46326.1 - 6.2e-35 118.8 0.1 9e-20 70.3 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY46326.1 - 7.6e-06 25.8 0.0 0.01 15.8 0.0 2.2 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 ORY46326.1 - 0.004 17.2 0.0 0.04 14.0 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif DUF1866 PF08952.11 ORY46326.1 - 0.0075 16.1 0.0 0.019 14.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1866) RRM_occluded PF16842.5 ORY46326.1 - 0.074 12.9 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif ODV-E18 PF10717.9 ORY46327.1 - 0.0013 18.5 1.4 0.0013 18.5 1.4 2.0 1 1 1 2 2 2 1 Occlusion-derived virus envelope protein ODV-E18 DUF4010 PF13194.6 ORY46327.1 - 0.0036 17.0 1.4 0.0041 16.8 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4010) DUF3671 PF12420.8 ORY46327.1 - 0.0094 16.0 8.5 0.01 15.9 8.5 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF5385 PF17359.2 ORY46327.1 - 0.01 15.4 1.5 0.01 15.4 1.5 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5385) DUF4293 PF14126.6 ORY46327.1 - 0.012 15.9 4.5 0.014 15.6 4.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) ABC_export PF16962.5 ORY46327.1 - 0.018 13.5 5.8 0.02 13.3 5.8 1.0 1 0 0 1 1 1 0 Putative ABC exporter DHHC PF01529.20 ORY46327.1 - 0.02 15.0 5.6 0.022 14.9 5.6 1.0 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF1600 PF07667.11 ORY46327.1 - 0.021 15.0 4.5 0.023 14.9 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1600) RDD PF06271.12 ORY46327.1 - 0.022 15.0 4.3 0.027 14.7 4.3 1.0 1 0 0 1 1 1 0 RDD family DUF2500 PF10694.9 ORY46327.1 - 0.051 14.1 0.8 0.051 14.1 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2500) PIG-F PF06699.11 ORY46327.1 - 0.053 13.7 4.6 0.055 13.6 4.6 1.0 1 0 0 1 1 1 0 GPI biosynthesis protein family Pig-F DUF898 PF05987.13 ORY46327.1 - 0.065 12.3 2.0 0.07 12.2 2.0 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Spo7 PF03907.13 ORY46327.1 - 0.079 12.4 3.4 0.09 12.2 3.4 1.0 1 0 0 1 1 1 0 Spo7-like protein DUF4131 PF13567.6 ORY46327.1 - 0.12 12.0 1.0 0.14 11.8 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1980 PF09323.10 ORY46327.1 - 0.28 11.1 4.0 0.31 10.9 4.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF973 PF06157.11 ORY46327.1 - 0.41 9.7 10.0 0.41 9.6 10.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF973) DUF3810 PF12725.7 ORY46327.1 - 0.6 9.4 4.5 0.72 9.1 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF4220 PF13968.6 ORY46327.1 - 0.93 8.8 3.5 1 8.7 3.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) DUF2207 PF09972.9 ORY46327.1 - 0.93 8.2 4.4 1.3 7.7 4.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) KASH PF10541.9 ORY46327.1 - 0.96 9.8 6.1 2.5 8.4 0.2 2.1 2 0 0 2 2 2 0 Nuclear envelope localisation domain COX2_TM PF02790.15 ORY46327.1 - 0.96 9.6 9.7 1.7 8.8 9.7 1.4 1 1 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain Phospholamban PF04272.14 ORY46327.1 - 1.6 8.3 12.3 0.81 9.2 0.2 2.1 2 0 0 2 2 2 0 Phospholamban DUF5383 PF17355.2 ORY46327.1 - 1.7 9.1 14.0 2.3 8.6 0.9 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5383) Pox_EPC_I2-L1 PF12575.8 ORY46327.1 - 4 7.7 16.2 5.2 7.4 7.0 2.1 1 1 1 2 2 2 0 Poxvirus entry protein complex L1 and I2 Tetraspanin PF00335.20 ORY46327.1 - 4.3 7.0 8.4 7.4 6.2 8.4 1.4 1 1 0 1 1 1 0 Tetraspanin family DUF3357 PF11837.8 ORY46327.1 - 5.7 7.4 5.3 1.2 9.7 0.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) DUF2116 PF09889.9 ORY46327.1 - 9.1 6.4 13.4 14 5.8 0.6 2.2 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) RRM_1 PF00076.22 ORY46328.1 - 1.4e-41 140.1 0.0 5.1e-23 80.7 0.0 2.0 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY46328.1 - 2.8e-07 30.6 0.0 0.0017 18.5 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 ORY46328.1 - 3.1e-06 27.0 0.0 0.0026 17.6 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 ORY46328.1 - 0.00094 19.0 0.0 0.3 10.9 0.0 2.5 2 1 1 3 3 3 2 Rrp7 RRM-like N-terminal domain RRM_3 PF08777.11 ORY46328.1 - 0.0081 16.2 0.0 0.079 13.0 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.6 ORY46328.1 - 0.041 13.9 0.0 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF4154 PF13689.6 ORY46328.1 - 0.061 13.6 0.0 0.19 12.0 0.0 1.6 1 1 1 2 2 2 0 YfiR/HmsC-like DbpA PF03880.15 ORY46328.1 - 0.079 13.0 0.0 6.3 6.9 0.0 2.4 2 0 0 2 2 2 0 DbpA RNA binding domain Nup88 PF10168.9 ORY46329.1 - 4.8e-30 104.0 14.2 8.4e-17 60.2 0.0 3.1 3 0 0 3 3 3 3 Nuclear pore component DeoRC PF00455.22 ORY46329.1 - 0.028 14.4 0.0 0.73 9.8 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain Peptidase_M3_N PF08439.10 ORY46329.1 - 0.95 9.8 4.0 0.63 10.4 0.8 2.3 2 0 0 2 2 2 0 Oligopeptidase F TPR_21 PF09976.9 ORY46329.1 - 1.3 8.7 6.9 2 8.1 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain DUF1664 PF07889.12 ORY46329.1 - 2.9 7.9 12.5 10 6.2 0.6 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) ISG65-75 PF11727.8 ORY46329.1 - 3.3 6.9 6.7 6 6.0 6.7 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein Fib_alpha PF08702.10 ORY46329.1 - 3.5 7.8 5.6 9.4 6.4 5.6 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF2205 PF10224.9 ORY46329.1 - 9.4 6.3 12.4 1.5 8.9 0.9 3.4 2 1 1 3 3 3 0 Short coiled-coil protein CBFB_NFYA PF02045.15 ORY46330.1 - 1.7e-11 44.6 2.8 3.5e-11 43.6 2.8 1.6 1 1 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Ank_2 PF12796.7 ORY46331.1 - 0.00023 21.7 3.5 0.001 19.6 0.5 2.8 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY46331.1 - 0.00035 21.1 0.8 0.0052 17.3 0.1 2.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY46331.1 - 0.001 19.4 1.0 0.41 11.3 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 ORY46331.1 - 0.16 12.4 0.4 1.4 9.4 0.1 2.5 2 1 0 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 ORY46331.1 - 0.35 11.4 6.2 0.9 10.1 0.1 3.3 2 1 0 2 2 2 0 Ankyrin repeat ZapB PF06005.12 ORY46332.1 - 4.7e-05 23.7 2.3 0.16 12.5 0.4 2.4 2 0 0 2 2 2 2 Cell division protein ZapB bZIP_1 PF00170.21 ORY46332.1 - 0.0031 17.6 1.3 0.72 10.0 0.0 2.5 2 0 0 2 2 2 1 bZIP transcription factor DivIC PF04977.15 ORY46332.1 - 0.0058 16.4 2.7 0.39 10.5 0.2 2.5 2 0 0 2 2 2 1 Septum formation initiator bZIP_2 PF07716.15 ORY46332.1 - 0.018 15.1 2.3 3.7 7.7 0.7 2.5 2 0 0 2 2 2 0 Basic region leucine zipper NRBF2 PF08961.10 ORY46332.1 - 0.022 14.3 2.4 0.29 10.7 0.3 2.2 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator DUF4201 PF13870.6 ORY46332.1 - 0.024 14.4 2.8 0.041 13.6 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) YabA PF06156.13 ORY46332.1 - 0.024 15.2 2.9 3.3 8.4 0.1 2.4 1 1 0 2 2 2 0 Initiation control protein YabA TSC22 PF01166.18 ORY46332.1 - 0.027 14.8 0.3 5.8 7.3 0.0 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family K-box PF01486.17 ORY46332.1 - 0.035 14.3 2.2 4.7 7.5 0.1 2.7 2 1 0 2 2 2 0 K-box region BLOC1_2 PF10046.9 ORY46332.1 - 0.042 14.2 4.0 0.38 11.1 1.1 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KASH_CCD PF14662.6 ORY46332.1 - 0.065 13.1 4.8 0.14 11.9 3.6 2.0 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH JIP_LZII PF16471.5 ORY46332.1 - 0.12 12.5 1.8 7.6 6.8 0.2 2.5 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF5082 PF16888.5 ORY46332.1 - 0.16 12.3 1.3 7 7.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Csm1_N PF18504.1 ORY46332.1 - 0.16 12.3 1.2 7.2 7.0 0.1 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain Spc24 PF08286.11 ORY46332.1 - 0.21 11.8 3.1 1.2 9.4 0.1 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Spc7 PF08317.11 ORY46332.1 - 0.69 8.7 5.4 1.5 7.6 5.0 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein WD40_alt PF14077.6 ORY46332.1 - 0.91 9.4 4.7 16 5.5 0.1 3.0 2 1 1 3 3 3 0 Alternative WD40 repeat motif ABC_tran_CTD PF16326.5 ORY46332.1 - 3.1 8.1 7.2 5.5 7.3 3.7 3.0 1 1 2 3 3 3 0 ABC transporter C-terminal domain RRM_1 PF00076.22 ORY46333.1 - 1.4e-17 63.3 0.0 1.6e-17 63.1 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 ORY46333.1 - 0.001 19.0 0.0 0.0021 18.0 0.0 1.5 1 1 0 1 1 1 1 RNA binding domain RRM_5 PF13893.6 ORY46333.1 - 0.066 12.8 0.0 0.075 12.6 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sialidase PF02973.16 ORY46334.1 - 0.092 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Sialidase, N-terminal domain PIP5K PF01504.18 ORY46335.1 - 9.6e-23 80.8 0.0 6e-14 51.9 0.0 2.0 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Peptidase_S24 PF00717.23 ORY46337.1 - 1.1e-07 31.7 0.9 1.9e-06 27.7 0.8 2.6 1 1 1 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 ORY46337.1 - 0.012 15.4 0.0 0.44 10.3 0.0 2.3 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 Abhydrolase_1 PF00561.20 ORY46338.1 - 1.2e-26 93.9 0.1 6.8e-26 91.4 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 ORY46338.1 - 0.00066 19.4 0.1 0.001 18.8 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 ORY46338.1 - 0.014 14.7 0.2 0.023 13.9 0.2 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 ORY46338.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 ORY46339.1 - 1.9e-30 106.4 0.6 4.4e-30 105.2 0.6 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 ORY46339.1 - 1.1e-05 25.3 0.1 1.6e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 ORY46339.1 - 0.0035 16.7 0.1 0.0053 16.1 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY46339.1 - 0.008 16.8 0.0 0.01 16.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2048 PF09752.9 ORY46339.1 - 0.079 12.0 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Rhomboid_SP PF12595.8 ORY46339.1 - 0.2 11.0 0.3 7.6 5.8 0.2 2.2 2 0 0 2 2 2 0 Rhomboid serine protease Aa_trans PF01490.18 ORY46340.1 - 3.1e-44 151.3 26.1 7e-34 117.2 9.5 3.0 1 1 2 3 3 3 3 Transmembrane amino acid transporter protein DUF202 PF02656.15 ORY46340.1 - 4.7 7.7 9.1 18 5.9 0.9 3.6 2 2 0 2 2 2 0 Domain of unknown function (DUF202) Aa_trans PF01490.18 ORY46342.1 - 1.3e-49 169.0 30.9 2.6e-35 121.9 15.0 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein CBM_1 PF00734.18 ORY46343.1 - 0.00096 19.1 10.4 0.35 10.9 0.4 3.8 3 1 0 3 3 3 2 Fungal cellulose binding domain EarP PF10093.9 ORY46343.1 - 0.0031 16.6 0.0 3.6 6.6 0.0 2.9 1 1 2 3 3 3 2 Elongation-Factor P (EF-P) rhamnosyltransferase EarP AnkUBD PF18418.1 ORY46343.1 - 0.039 14.1 0.8 5.7 7.2 0.0 3.1 3 0 0 3 3 3 0 Ankyrin ubiquitin-binding domain zf_CCCH_4 PF18345.1 ORY46343.1 - 0.058 13.5 0.9 1.2 9.3 0.0 2.6 2 0 0 2 2 2 0 Zinc finger domain SKG6 PF08693.10 ORY46343.1 - 1 8.8 3.3 35 3.9 0.1 3.2 3 0 0 3 3 3 0 Transmembrane alpha-helix domain CAF1 PF04857.20 ORY46344.1 - 1.3e-25 90.2 0.1 2.1e-25 89.6 0.1 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease RNA_bind PF08675.11 ORY46344.1 - 0.014 15.4 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 RNA binding domain LRR_8 PF13855.6 ORY46345.1 - 1.4e-08 34.3 1.5 2.3e-06 27.3 0.1 2.8 1 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 ORY46345.1 - 2.3e-06 27.8 2.9 0.073 13.5 0.1 3.2 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY46345.1 - 7.9e-05 22.7 5.7 5 8.1 0.5 4.1 3 1 0 3 3 3 3 Leucine Rich Repeat LRR_6 PF13516.6 ORY46345.1 - 0.066 13.3 2.2 5.1 7.4 0.1 3.7 4 0 0 4 4 4 0 Leucine Rich repeat CFEM PF05730.11 ORY46347.1 - 0.015 15.4 18.9 0.017 15.2 3.4 3.7 3 1 0 3 3 3 0 CFEM domain ABA_WDS PF02496.16 ORY46347.1 - 0.094 13.2 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 ABA/WDS induced protein TMEM154 PF15102.6 ORY46348.1 - 0.0081 16.1 2.7 0.0094 15.9 0.0 2.3 3 0 0 3 3 3 1 TMEM154 protein family Shisa PF13908.6 ORY46348.1 - 0.01 16.1 0.0 0.01 16.1 0.0 2.2 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator Hum_adeno_E3A PF05393.11 ORY46348.1 - 0.024 14.6 0.1 0.082 12.9 0.1 1.9 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein LRRC37AB_C PF14914.6 ORY46348.1 - 0.038 13.9 0.3 0.16 11.9 0.3 1.8 1 1 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain WBP-1 PF11669.8 ORY46348.1 - 0.048 14.3 1.4 0.064 13.9 0.2 1.8 2 0 0 2 2 2 0 WW domain-binding protein 1 TFCD_C PF12612.8 ORY46348.1 - 0.075 12.8 0.2 0.15 11.9 0.1 1.5 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal TMEM51 PF15345.6 ORY46348.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Transmembrane protein 51 DUF5304 PF17230.2 ORY46349.1 - 0.017 15.3 0.9 0.028 14.6 0.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5304) ATP-gua_PtransN PF02807.15 ORY46351.1 - 1.8e-09 37.9 87.3 1.4e+02 3.0 0.0 31.4 35 0 0 35 35 35 0 ATP:guanido phosphotransferase, N-terminal domain KCT2 PF17818.1 ORY46351.1 - 0.73 9.9 6.8 16 5.6 0.1 5.1 4 0 0 4 4 4 0 Keratinocyte-associated gene product Herpes_UL6 PF01763.16 ORY46351.1 - 5.2 5.5 6.9 87 1.4 0.0 6.1 5 2 1 6 6 6 0 Herpesvirus UL6 like Peptidase_M16_M PF16187.5 ORY46352.1 - 1.9e-82 276.7 0.0 3.4e-82 275.9 0.0 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 ORY46352.1 - 4e-39 134.0 0.0 8.7e-39 132.9 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 ORY46352.1 - 1.6e-29 103.2 0.0 4.8e-19 69.1 0.0 2.3 2 0 0 2 2 2 2 Peptidase M16 inactive domain DUF2315 PF10231.9 ORY46352.1 - 0.014 15.5 3.7 3.2 7.9 0.0 3.2 3 0 0 3 3 3 0 Apoptogenic protein 1 F-box PF00646.33 ORY46354.1 - 8.6e-07 28.7 1.9 1.7e-06 27.7 1.9 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY46354.1 - 1.7e-05 24.6 0.5 3.2e-05 23.7 0.5 1.4 1 0 0 1 1 1 1 F-box-like MTES_1575 PF18741.1 ORY46355.1 - 4.2 7.6 7.1 2.8 8.2 4.8 1.9 1 1 1 2 2 2 0 REase_MTES_1575 Ank_2 PF12796.7 ORY46356.1 - 1.8e-14 54.1 0.0 1.4e-05 25.6 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY46356.1 - 7.7e-09 35.1 1.0 0.047 14.3 0.0 6.4 6 1 1 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 ORY46356.1 - 1.3e-07 31.7 0.5 0.47 10.8 0.0 5.5 2 1 4 6 6 6 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY46356.1 - 1.7e-07 31.7 0.5 0.0009 19.8 0.0 4.5 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY46356.1 - 7.8e-05 23.0 0.7 0.83 10.2 0.0 4.8 6 0 0 6 6 6 2 Ankyrin repeat F-box_4 PF15966.5 ORY46356.1 - 0.04 13.8 0.1 0.068 13.1 0.1 1.3 1 0 0 1 1 1 0 F-box CrgA PF06781.12 ORY46358.1 - 0.096 12.8 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Cell division protein CrgA SIMPL PF04402.14 ORY46359.1 - 0.23 11.9 3.8 0.43 11.0 1.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF541) PfkB PF00294.24 ORY46360.1 - 4.5e-15 55.7 0.8 1.2e-13 51.0 0.8 2.1 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Myosin_head PF00063.21 ORY46361.1 - 6.5e-12 44.5 0.0 1.2e-10 40.3 0.0 2.0 2 0 0 2 2 2 2 Myosin head (motor domain) Myosin_head PF00063.21 ORY46362.1 - 0.2 9.8 0.0 0.27 9.4 0.0 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) Chitin_synth_2 PF03142.15 ORY46363.1 - 8.3e-137 457.0 6.9 3.1e-82 276.9 0.1 3.1 1 1 2 3 3 3 3 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORY46363.1 - 1.2e-05 25.3 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ORY46363.1 - 1.3e-05 25.0 0.0 2.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 ORY46363.1 - 0.0016 18.4 4.7 0.0031 17.5 4.7 1.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Pkinase PF00069.25 ORY46367.1 - 1.2e-68 231.3 0.0 1.5e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY46367.1 - 1.4e-36 126.1 0.0 1.7e-36 125.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY46367.1 - 4.6e-05 22.9 0.0 7.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY46367.1 - 0.0016 18.4 0.1 0.32 10.9 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 ORY46367.1 - 0.055 12.8 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC1 PF03109.16 ORY46367.1 - 0.097 12.8 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 ABC1 family POR PF01558.18 ORY46367.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Haspin_kinase PF12330.8 ORY46367.1 - 0.22 10.4 0.2 0.31 9.9 0.2 1.2 1 0 0 1 1 1 0 Haspin like kinase domain CR6_interact PF10147.9 ORY46370.1 - 7.6 6.2 9.7 11 5.7 4.9 2.3 1 1 1 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Viral_helicase1 PF01443.18 ORY46371.1 - 0.00018 21.3 0.0 0.17 11.6 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 ORY46371.1 - 0.0093 15.7 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY46371.1 - 0.13 12.8 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 ORY46371.1 - 0.21 10.8 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) zf-H3C2 PF16721.5 ORY46374.1 - 0.18 12.2 0.1 0.34 11.3 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger like, probable DNA-binding DUF3421 PF11901.8 ORY46377.1 - 4.1e-14 52.5 0.5 3e-07 30.4 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3421) Ank_2 PF12796.7 ORY46378.1 - 4.2e-17 62.5 0.0 3e-12 47.0 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY46378.1 - 1.9e-11 43.1 0.0 2.3e-06 27.5 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 ORY46378.1 - 4.5e-10 39.8 0.0 1.1e-09 38.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 ORY46378.1 - 4.6e-09 36.3 0.0 4.1e-06 27.0 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 ORY46378.1 - 1e-07 32.1 0.1 4.2e-06 26.9 0.0 2.8 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Pox_Ag35 PF03286.14 ORY46379.1 - 9.3 6.0 9.5 16 5.3 2.8 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein UQ_con PF00179.26 ORY46381.1 - 3.8e-46 156.2 0.0 4.4e-46 156.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY46381.1 - 0.00016 21.4 0.0 0.00017 21.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 ORY46381.1 - 0.072 13.4 0.0 0.14 12.4 0.0 1.5 1 1 0 1 1 1 0 RWD domain DUF3772 PF12607.8 ORY46384.1 - 0.11 12.3 1.1 0.21 11.4 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) PH PF00169.29 ORY46385.1 - 0.0006 20.3 0.0 0.0012 19.3 0.0 1.5 1 0 0 1 1 1 1 PH domain PH PF00169.29 ORY46386.1 - 0.11 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 PH domain Wtap PF17098.5 ORY46389.1 - 0.13 12.2 0.9 0.45 10.4 0.9 2.0 1 1 0 1 1 1 0 WTAP/Mum2p family Spc29 PF17082.5 ORY46389.1 - 1.3 8.8 5.7 2.3 8.0 0.7 2.3 1 1 2 3 3 3 0 Spindle Pole Component 29 BST2 PF16716.5 ORY46390.1 - 0.071 13.7 0.2 0.63 10.7 0.0 2.3 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 RRF PF01765.19 ORY46391.1 - 2e-29 102.7 10.9 2.7e-29 102.2 10.9 1.1 1 0 0 1 1 1 1 Ribosome recycling factor Tim17 PF02466.19 ORY46392.1 - 1.3e-14 54.5 0.2 2.3e-14 53.7 0.2 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TIP49 PF06068.13 ORY46393.1 - 2.6e-90 303.1 4.9 1.9e-89 300.3 4.9 2.2 1 1 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 ORY46393.1 - 1.6e-16 60.2 1.1 9.4e-15 54.5 1.1 2.8 1 1 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 ORY46393.1 - 3.1e-08 34.1 0.5 0.00014 22.3 0.1 2.9 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 ORY46393.1 - 0.00019 20.8 0.4 0.00041 19.8 0.1 1.7 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 ORY46393.1 - 0.0014 19.0 0.1 0.0072 16.7 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ORY46393.1 - 0.0018 18.3 0.1 0.026 14.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY46393.1 - 0.0023 18.2 0.7 0.16 12.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 ORY46393.1 - 0.0024 17.3 0.3 0.045 13.1 0.1 2.8 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 ORY46393.1 - 0.0068 16.6 0.2 0.069 13.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 ORY46393.1 - 0.019 15.4 1.6 0.047 14.1 0.2 2.3 2 1 0 2 2 2 0 AAA domain RuvB_N PF05496.12 ORY46393.1 - 0.039 13.7 0.6 2.9 7.6 0.1 2.6 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 ORY46393.1 - 3.2 8.1 7.7 5.9 7.2 4.8 2.6 2 1 0 2 2 2 0 AAA domain Pyr_redox_2 PF07992.14 ORY46394.1 - 0.015 14.6 0.0 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase LRR_8 PF13855.6 ORY46395.1 - 1.6e-17 63.0 46.8 8.2e-09 35.1 5.2 4.8 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 ORY46395.1 - 1.6e-14 53.8 27.3 6.4e-05 23.2 2.0 5.4 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY46395.1 - 6.3e-12 44.3 19.1 0.054 14.1 0.1 7.8 8 0 0 8 8 8 4 Leucine Rich Repeat LRR_6 PF13516.6 ORY46395.1 - 5.9e-05 22.8 19.3 1.4 9.2 0.1 7.7 8 0 0 8 8 8 3 Leucine Rich repeat CRAL_TRIO PF00650.20 ORY46396.1 - 3.1e-13 49.8 0.0 4.8e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Dus PF01207.17 ORY46396.1 - 0.0063 15.6 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) G-patch_2 PF12656.7 ORY46399.1 - 9.6e-20 70.4 1.0 1.3e-19 70.0 0.1 1.8 2 0 0 2 2 2 1 G-patch domain RTP1_C1 PF10363.9 ORY46400.1 - 2.8e-21 75.8 0.3 4.7e-20 71.9 0.1 3.2 3 1 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 CENP-B_dimeris PF09026.10 ORY46401.1 - 3.6 8.0 7.9 7 7.1 7.9 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop25 PF09805.9 ORY46402.1 - 4.7e-09 36.8 4.9 8e-09 36.1 4.9 1.4 1 0 0 1 1 1 1 Nucleolar protein 12 (25kDa) Sas10_Utp3 PF04000.15 ORY46403.1 - 5e-11 43.1 0.0 5e-11 43.1 0.0 2.0 2 1 0 2 2 2 1 Sas10/Utp3/C1D family Fungal_trans PF04082.18 ORY46405.1 - 1.7e-20 73.2 0.0 5.3e-20 71.6 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Lipase_GDSL_2 PF13472.6 ORY46406.1 - 0.029 14.8 0.1 0.064 13.7 0.1 1.6 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DUF1488 PF07369.11 ORY46406.1 - 0.033 14.2 0.0 0.097 12.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) DIM1 PF02966.16 ORY46408.1 - 1.9e-67 225.1 0.2 2.1e-67 224.9 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 ORY46408.1 - 2.3e-06 27.5 0.1 3e-06 27.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin VanZ PF04892.12 ORY46409.1 - 1.9e-06 28.6 0.1 3e-06 27.9 0.1 1.3 1 1 0 1 1 1 1 VanZ like family SQS_PSY PF00494.19 ORY46410.1 - 1.1e-20 74.3 0.1 2.3e-20 73.2 0.0 1.5 2 0 0 2 2 2 1 Squalene/phytoene synthase SQS_PSY PF00494.19 ORY46411.1 - 4.5e-16 59.2 0.0 5.1e-16 59.0 0.0 1.0 1 0 0 1 1 1 1 Squalene/phytoene synthase RCC1_2 PF13540.6 ORY46412.1 - 3e-18 65.1 10.1 3.3e-10 39.5 2.4 4.0 3 1 1 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 ORY46412.1 - 1.7e-15 57.4 2.1 1.9e-05 25.1 0.0 4.2 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat CH_2 PF06294.11 ORY46413.1 - 2.4e-08 34.0 0.0 5.2e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 CH-like domain in sperm protein EF-hand_7 PF13499.6 ORY46414.1 - 4.2e-29 100.8 4.1 2.9e-14 53.3 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORY46414.1 - 3.3e-28 95.1 8.4 9.9e-07 27.9 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 ORY46414.1 - 5.7e-24 83.7 11.5 5.1e-11 42.3 0.9 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 ORY46414.1 - 1.2e-21 74.7 3.4 1.6e-05 24.4 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_9 PF14658.6 ORY46414.1 - 1.5e-15 57.3 0.7 2.9e-08 33.9 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 ORY46414.1 - 8.3e-13 47.2 5.8 0.052 13.1 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_4 PF12763.7 ORY46414.1 - 6.7e-07 29.2 4.0 0.031 14.2 0.9 2.9 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORY46414.1 - 4.6e-05 23.7 1.2 0.24 11.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 ORY46414.1 - 0.013 15.7 1.0 0.013 15.7 1.0 2.3 2 2 0 2 2 2 0 Dockerin type I domain TSP_3 PF02412.18 ORY46414.1 - 0.044 13.5 0.2 0.044 13.5 0.2 2.7 4 0 0 4 4 4 0 Thrombospondin type 3 repeat Toprim_4 PF13662.6 ORY46414.1 - 0.083 13.4 0.2 1.3 9.6 0.2 2.4 1 1 0 1 1 1 0 Toprim domain Bile_Hydr_Trans PF04775.14 ORY46414.1 - 0.1 12.7 0.0 0.8 9.8 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region UPF0154 PF03672.13 ORY46414.1 - 0.13 12.4 0.0 0.69 10.0 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) CBS PF00571.28 ORY46415.1 - 2.3e-13 50.4 8.2 0.0014 19.0 0.0 4.5 5 0 0 5 5 5 3 CBS domain Urease_linker PF18473.1 ORY46415.1 - 0.074 12.9 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Urease subunit beta-alpha linker domain PB1 PF00564.24 ORY46415.1 - 0.1 12.6 0.0 0.52 10.3 0.0 2.2 2 0 0 2 2 2 0 PB1 domain CIA30 PF08547.12 ORY46416.1 - 3.1e-19 69.6 0.2 3.8e-19 69.3 0.2 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Retro_M PF02813.14 ORY46416.1 - 0.039 14.3 0.0 0.054 13.9 0.0 1.3 1 0 0 1 1 1 0 Retroviral M domain DUF3579 PF12112.8 ORY46416.1 - 0.19 12.3 0.0 0.25 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3579) LRR_4 PF12799.7 ORY46417.1 - 3.1e-21 75.1 35.7 6.7e-07 29.5 0.7 6.5 2 1 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY46417.1 - 3e-17 62.1 30.0 6.8e-07 29.0 8.1 6.0 3 3 2 5 5 5 5 Leucine rich repeat LRR_1 PF00560.33 ORY46417.1 - 7.9e-11 40.9 40.7 0.21 12.3 0.2 11.3 11 2 0 11 11 11 4 Leucine Rich Repeat F-box-like PF12937.7 ORY46417.1 - 1.3e-07 31.4 1.3 3.2e-07 30.2 1.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY46417.1 - 1.5e-07 31.1 0.7 3.8e-07 29.8 0.7 1.7 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.6 ORY46417.1 - 1.5 9.1 28.2 2.8 8.2 0.2 7.8 9 0 0 9 9 9 0 Leucine Rich repeat FAM176 PF14851.6 ORY46418.1 - 0.038 13.6 0.0 0.051 13.2 0.0 1.1 1 0 0 1 1 1 0 FAM176 family UPF0560 PF10577.9 ORY46418.1 - 0.073 11.6 0.8 0.096 11.2 0.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4736 PF15883.5 ORY46419.1 - 0.27 11.0 0.0 0.34 10.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4736) F-box-like PF12937.7 ORY46420.1 - 3.6e-07 30.0 0.1 1.1e-06 28.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY46420.1 - 6.7e-05 22.7 0.1 0.00017 21.4 0.1 1.6 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.33 ORY46420.1 - 0.00031 20.9 3.1 0.43 11.3 1.8 2.9 2 0 0 2 2 2 2 Leucine Rich Repeat LRR_8 PF13855.6 ORY46420.1 - 0.0019 17.9 0.4 0.0036 17.0 0.4 1.4 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 ORY46420.1 - 0.091 13.2 1.2 0.26 11.8 0.9 1.9 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORY46421.1 - 6.4e-06 26.0 1.0 1.1e-05 25.3 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY46421.1 - 0.00012 21.9 0.1 0.00076 19.3 0.0 2.2 2 1 0 2 2 2 1 F-box domain DUF5131 PF07505.11 ORY46421.1 - 0.002 17.7 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF5131) Phi_1 PF04674.12 ORY46422.1 - 3.3e-17 62.7 0.8 1.1e-16 61.0 0.8 1.8 1 1 0 1 1 1 1 Phosphate-induced protein 1 conserved region LRR_8 PF13855.6 ORY46422.1 - 6.8e-05 22.6 4.1 9e-05 22.2 0.6 2.4 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 ORY46422.1 - 0.00018 21.8 10.2 0.0017 18.7 2.4 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY46422.1 - 2.7 8.3 8.2 47 4.4 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich repeat Helitron_like_N PF14214.6 ORY46423.1 - 0.002 18.4 0.0 0.0049 17.1 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus IGPS PF00218.21 ORY46425.1 - 1.3e-85 286.6 0.1 3.6e-85 285.2 0.0 1.7 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 ORY46425.1 - 6e-49 166.4 0.0 1e-48 165.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.22 ORY46425.1 - 1e-29 103.7 0.0 4.7e-23 82.0 0.0 2.5 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.13 ORY46425.1 - 1.7e-07 31.2 0.0 6.2e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 FMN_dh PF01070.18 ORY46425.1 - 0.00023 20.3 1.8 0.0023 17.0 0.5 2.8 3 0 0 3 3 3 1 FMN-dependent dehydrogenase GN3L_Grn1 PF08701.11 ORY46425.1 - 0.085 13.0 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 GNL3L/Grn1 putative GTPase QRPTase_C PF01729.19 ORY46425.1 - 0.16 11.8 0.3 0.74 9.6 0.2 2.0 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain DIM1 PF02966.16 ORY46426.1 - 1.4e-59 199.6 0.0 1.6e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 ORY46426.1 - 6.1e-05 22.9 0.0 8e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thiolase_N PF00108.23 ORY46427.1 - 1.4e-76 257.3 4.3 2e-76 256.8 4.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY46427.1 - 1.9e-44 150.3 0.7 5.8e-44 148.7 0.3 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ORY46427.1 - 0.0047 16.5 1.2 0.021 14.4 0.3 2.3 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 ORY46427.1 - 0.081 13.1 0.0 0.29 11.3 0.0 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal LRR_8 PF13855.6 ORY46428.1 - 2.9e-06 26.9 2.3 4.5e-06 26.3 2.3 1.3 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 ORY46428.1 - 0.0002 21.7 4.6 0.026 15.0 0.3 2.1 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY46428.1 - 0.06 13.9 4.4 13 6.8 0.2 3.2 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 ORY46428.1 - 0.28 11.3 2.7 6.1 7.2 0.1 3.1 3 0 0 3 3 3 0 Leucine Rich repeat LRR_4 PF12799.7 ORY46429.1 - 3.9e-09 36.7 15.6 0.00047 20.5 0.7 3.4 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY46429.1 - 2.4e-07 30.4 17.6 0.00039 20.1 4.0 3.5 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 ORY46429.1 - 7.6e-05 22.7 22.5 0.96 10.3 0.2 6.6 6 1 1 7 7 7 3 Leucine Rich Repeat zf-C2H2_4 PF13894.6 ORY46430.1 - 0.0019 18.9 20.9 1.3 10.1 2.3 4.6 3 1 1 4 4 4 2 C2H2-type zinc finger KNOX2 PF03791.13 ORY46430.1 - 0.097 12.2 0.2 5 6.7 0.0 2.8 3 0 0 3 3 3 0 KNOX2 domain zf-C2H2_3rep PF18868.1 ORY46430.1 - 1.4 9.6 5.3 9.2 7.0 0.5 2.6 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-ribbon_3 PF13248.6 ORY46430.1 - 2.6 7.6 9.1 0.48 9.9 4.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc-ribbons_6 PF07191.12 ORY46430.1 - 4 7.5 8.3 0.46 10.5 2.0 2.4 3 0 0 3 3 3 0 zinc-ribbons zf-C2H2 PF00096.26 ORY46430.1 - 6.7 7.4 23.7 4.4 8.0 2.1 4.6 3 1 1 4 4 4 0 Zinc finger, C2H2 type zf-met PF12874.7 ORY46430.1 - 8 7.0 9.6 17 5.9 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf_C2H2_6 PF18450.1 ORY46430.1 - 8.9 6.1 8.4 15 5.4 0.4 2.5 2 0 0 2 2 2 0 Zinc Finger domain zf-H2C2_2 PF13465.6 ORY46431.1 - 4.5e-05 23.7 5.4 0.026 14.9 0.2 2.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_8 PF15909.5 ORY46431.1 - 0.0011 19.2 3.5 0.0043 17.3 3.5 2.0 1 1 0 1 1 1 1 C2H2-type zinc ribbon zf-Di19 PF05605.12 ORY46431.1 - 0.045 14.1 1.9 0.045 14.1 1.9 1.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 ORY46431.1 - 0.05 14.4 15.8 0.76 10.8 2.3 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 ORY46431.1 - 0.32 11.0 2.2 5.1 7.1 0.1 2.9 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 ORY46431.1 - 0.33 11.5 13.1 2.2 8.9 0.1 4.0 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-RING_2 PF13639.6 ORY46431.1 - 2.3 8.6 7.3 19 5.7 0.2 3.2 3 0 0 3 3 3 0 Ring finger domain zf-H2C2_2 PF13465.6 ORY46433.1 - 1.5e-05 25.2 8.0 2.6e-05 24.4 0.6 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 ORY46433.1 - 0.0095 16.3 3.2 0.21 12.1 0.4 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type DUF2256 PF10013.9 ORY46433.1 - 0.14 12.3 0.2 0.14 12.3 0.2 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_4 PF13894.6 ORY46433.1 - 0.68 10.9 0.2 0.68 10.9 0.2 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2HE PF16278.5 ORY46433.1 - 1.1 9.7 10.6 0.86 10.1 0.7 3.0 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger ZapB PF06005.12 ORY46434.1 - 0.31 11.5 3.4 0.81 10.2 3.4 1.6 1 0 0 1 1 1 0 Cell division protein ZapB SKA1 PF07160.12 ORY46434.1 - 8 6.2 6.7 3.8 7.3 0.3 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF1664 PF07889.12 ORY46435.1 - 0.039 14.0 0.0 0.05 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HECT PF00632.25 ORY46437.1 - 1.6e-25 90.3 0.0 5.3e-11 42.6 0.0 3.7 2 1 0 3 3 3 2 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 ORY46437.1 - 3.3e-19 69.2 12.0 0.00015 22.3 0.0 7.0 6 2 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY46437.1 - 9e-16 57.2 17.1 8.8e-09 35.0 0.4 5.4 4 1 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat PCM1_C PF15717.5 ORY46437.1 - 0.091 11.5 4.2 0.13 10.9 4.2 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus Amelogenin PF02948.15 ORY46437.1 - 0.15 12.7 2.6 1.2 9.8 0.9 2.3 2 0 0 2 2 2 0 Amelogenin Pro-kuma_activ PF09286.11 ORY46437.1 - 0.19 12.0 0.1 0.45 10.8 0.1 1.5 1 0 0 1 1 1 0 Pro-kumamolisin, activation domain ATP-synt_Eps PF04627.13 ORY46442.1 - 5.1e-15 55.2 0.8 6.5e-15 54.9 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain AAA_18 PF13238.6 ORY46443.1 - 2.3e-25 89.7 0.2 4.2e-25 88.8 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 ORY46443.1 - 1.7e-05 25.2 0.5 3.7e-05 24.2 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 ORY46443.1 - 0.00049 20.4 0.2 0.00067 19.9 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 ORY46443.1 - 0.0023 18.3 1.1 0.0036 17.7 0.4 1.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ORY46443.1 - 0.0042 16.8 0.0 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 ORY46443.1 - 0.0084 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 ORY46443.1 - 0.013 14.7 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ADK PF00406.22 ORY46443.1 - 0.016 15.3 1.0 0.45 10.6 1.0 2.2 1 1 0 1 1 1 0 Adenylate kinase AAA_16 PF13191.6 ORY46443.1 - 0.018 15.4 0.0 0.028 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 ORY46443.1 - 0.019 14.4 0.9 0.12 11.7 0.1 2.1 2 0 0 2 2 2 0 KaiC ResIII PF04851.15 ORY46443.1 - 0.019 15.0 0.0 0.025 14.6 0.0 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.18 ORY46443.1 - 0.021 14.2 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SSE PF00437.20 ORY46443.1 - 0.033 13.2 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 ORY46443.1 - 0.052 13.8 0.7 0.14 12.5 0.2 1.8 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 ORY46443.1 - 0.061 13.5 0.1 0.36 11.0 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.6 ORY46443.1 - 0.073 12.8 0.0 0.4 10.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORY46443.1 - 0.092 13.1 2.0 0.21 11.9 1.9 1.7 1 1 0 1 1 1 0 AAA domain Dabb PF07876.12 ORY46443.1 - 0.11 13.2 0.3 0.38 11.4 0.0 2.0 2 1 0 2 2 2 0 Stress responsive A/B Barrel Domain Zeta_toxin PF06414.12 ORY46443.1 - 0.14 11.4 0.2 0.56 9.4 0.1 1.8 1 1 0 1 1 1 0 Zeta toxin RRM_1 PF00076.22 ORY46445.1 - 2.7e-17 62.3 0.0 4.2e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY46445.1 - 0.028 14.4 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 ORY46445.1 - 0.035 13.7 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zinc_ribbon_6 PF14599.6 ORY46446.1 - 3.3e-22 78.3 6.7 3.3e-22 78.3 6.7 4.8 3 1 2 5 5 5 1 Zinc-ribbon zf-CHY PF05495.12 ORY46446.1 - 8.3e-19 67.9 22.4 8.3e-19 67.9 22.4 3.8 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 ORY46446.1 - 4.1e-08 33.4 10.8 4.1e-08 33.4 10.8 5.3 3 1 1 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY46446.1 - 0.00043 20.1 12.8 0.00043 20.1 12.8 5.0 6 2 1 7 7 7 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY46446.1 - 0.0052 16.5 6.4 0.0052 16.5 6.4 4.1 5 0 0 5 5 5 1 RING-like zinc finger YL1 PF05764.13 ORY46446.1 - 0.1 12.7 18.0 0.17 12.0 18.0 1.2 1 0 0 1 1 1 0 YL1 nuclear protein eIF-3c_N PF05470.12 ORY46446.1 - 2.3 6.5 12.4 3.4 5.9 12.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Pro_CA PF00484.19 ORY46447.1 - 2.7e-46 157.7 0.0 1.5e-43 148.8 0.0 2.1 2 0 0 2 2 2 2 Carbonic anhydrase Ribosomal_L23eN PF03939.13 ORY46448.1 - 1.2e-21 76.6 7.6 2.1e-21 75.9 7.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 ORY46448.1 - 5e-13 49.2 3.0 5e-13 49.2 3.0 2.7 2 2 0 2 2 2 1 Ribosomal protein L23 PIG-X PF08320.12 ORY46450.1 - 1.5e-08 34.8 0.0 0.0056 16.6 0.0 2.6 2 0 0 2 2 2 2 PIG-X / PBN1 Peptidase_M3 PF01432.20 ORY46451.1 - 8.7e-88 295.6 0.6 4.5e-86 289.9 0.3 2.4 1 1 1 2 2 2 2 Peptidase family M3 Peptidase_M50B PF13398.6 ORY46451.1 - 0.18 11.4 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Peptidase_M91 PF14891.6 ORY46451.1 - 0.18 12.1 0.0 0.32 11.3 0.0 1.3 1 0 0 1 1 1 0 Effector protein Lum_binding PF00677.17 ORY46453.1 - 1.8e-35 120.8 0.8 8.3e-21 73.8 0.4 2.2 2 0 0 2 2 2 2 Lumazine binding domain NAD_binding_1 PF00175.21 ORY46454.1 - 2.3e-32 111.9 0.0 5e-32 110.8 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ORY46454.1 - 3e-15 56.4 0.0 2e-12 47.3 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ORY46454.1 - 1.4e-06 28.5 0.0 0.00017 21.7 0.0 2.1 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 ORY46456.1 - 2e-28 98.6 0.0 3.3e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ORY46456.1 - 5.3e-18 65.7 0.0 8.2e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_9 PF08021.11 ORY46456.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Aldo_ket_red PF00248.21 ORY46457.1 - 4.2e-42 144.3 0.1 1.3e-30 106.6 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family AAA_lid_11 PF18198.1 ORY46457.1 - 0.19 11.5 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain FAD_binding_3 PF01494.19 ORY46458.1 - 3.4e-17 62.7 0.0 6.3e-09 35.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.22 ORY46458.1 - 2.2e-06 27.0 0.1 3e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.24 ORY46458.1 - 5.9e-06 26.1 1.2 0.00071 19.3 2.7 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY46458.1 - 1.3e-05 24.6 0.3 0.00025 20.4 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 ORY46458.1 - 9.4e-05 21.6 0.0 0.062 12.3 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase 3HCDH_N PF02737.18 ORY46458.1 - 0.00023 21.1 0.1 0.00043 20.2 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 ORY46458.1 - 0.00031 20.9 0.2 0.00061 20.0 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY46458.1 - 0.0054 17.3 1.5 0.0096 16.5 0.4 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY46458.1 - 0.024 13.5 0.3 2.2 7.0 0.2 2.2 2 0 0 2 2 2 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 ORY46458.1 - 0.024 13.9 0.1 0.04 13.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 ORY46458.1 - 0.14 11.2 1.1 0.25 10.4 1.1 1.3 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 ORY46458.1 - 0.15 11.6 0.1 0.31 10.6 0.1 1.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RRM_9 PF18444.1 ORY46459.1 - 0.044 13.6 0.0 0.053 13.4 0.0 1.1 1 0 0 1 1 1 0 RNA recognition motif Syja_N PF02383.18 ORY46460.1 - 0.0035 16.7 0.0 0.004 16.5 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Syja_N PF02383.18 ORY46461.1 - 1.3e-18 67.4 0.0 8.1e-17 61.5 0.0 2.3 1 1 0 1 1 1 1 SacI homology domain Pkinase PF00069.25 ORY46462.1 - 8.2e-66 222.1 0.0 1e-65 221.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY46462.1 - 1.3e-36 126.3 0.0 1.7e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY46462.1 - 0.0017 17.7 0.0 0.0034 16.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY46462.1 - 0.11 11.4 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF3421 PF11901.8 ORY46463.1 - 6.5e-22 77.7 0.1 1.2e-10 41.3 0.0 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) Peptidase_C92 PF05708.12 ORY46463.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family AAA_23 PF13476.6 ORY46464.1 - 2.3e-16 60.9 1.7 2.3e-16 60.9 1.7 4.8 2 2 2 4 4 4 1 AAA domain SMC_N PF02463.19 ORY46464.1 - 1.3e-11 44.4 24.2 1e-10 41.4 23.9 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ORY46464.1 - 0.00066 19.6 0.3 0.2 11.4 0.1 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system B3 PF02362.21 ORY46464.1 - 0.087 12.7 0.1 0.28 11.1 0.1 1.8 1 0 0 1 1 1 0 B3 DNA binding domain ArfGap PF01412.18 ORY46465.1 - 2.9e-29 101.5 0.1 3.1e-29 101.4 0.1 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ROS_MUCR PF05443.11 ORY46465.1 - 0.038 14.0 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein ABC_membrane PF00664.23 ORY46466.1 - 7.5e-61 206.2 37.4 2.6e-39 135.5 14.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY46466.1 - 3.9e-48 163.5 1.2 3.5e-24 85.9 0.1 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY46466.1 - 1.6e-14 53.9 6.1 0.00027 20.4 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY46466.1 - 5.1e-08 33.0 0.7 0.0064 16.6 0.2 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY46466.1 - 5.6e-07 29.2 3.5 0.013 15.2 0.3 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 ORY46466.1 - 7.9e-07 29.8 1.1 0.06 13.8 0.7 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 ORY46466.1 - 1e-05 25.5 0.4 0.0067 16.3 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 ORY46466.1 - 6.5e-05 23.4 0.1 0.26 11.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 ORY46466.1 - 7.5e-05 22.9 3.6 0.0023 18.0 0.6 2.6 2 0 0 2 2 2 1 Dynamin family AAA_21 PF13304.6 ORY46466.1 - 0.00012 22.0 8.7 0.11 12.2 0.4 3.7 2 2 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 ORY46466.1 - 0.00026 20.8 1.7 0.43 10.2 0.2 2.3 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 ORY46466.1 - 0.0012 19.0 4.8 0.11 12.5 0.1 3.2 3 0 0 3 3 3 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 ORY46466.1 - 0.0014 18.0 0.8 1.5 8.2 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_22 PF13401.6 ORY46466.1 - 0.0018 18.6 0.6 1.8 8.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ORY46466.1 - 0.0022 17.3 1.6 0.16 11.2 0.1 2.8 3 0 0 3 3 3 1 Zeta toxin NB-ARC PF00931.22 ORY46466.1 - 0.0039 16.4 0.2 0.78 8.9 0.1 2.7 2 0 0 2 2 2 1 NB-ARC domain cobW PF02492.19 ORY46466.1 - 0.0048 16.5 1.2 0.047 13.3 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 ORY46466.1 - 0.0056 15.9 1.8 0.59 9.3 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 ORY46466.1 - 0.006 16.1 0.3 2.1 7.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Roc PF08477.13 ORY46466.1 - 0.0072 16.5 0.3 3.2 8.0 0.1 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 ORY46466.1 - 0.0086 15.2 0.1 2.4 7.1 0.1 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 ORY46466.1 - 0.013 14.5 0.4 0.93 8.3 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.17 ORY46466.1 - 0.018 14.8 0.5 0.24 11.1 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_30 PF13604.6 ORY46466.1 - 0.025 14.3 1.9 4.7 6.9 0.1 2.8 2 1 0 2 2 2 0 AAA domain NACHT PF05729.12 ORY46466.1 - 0.034 14.1 1.3 6.2 6.7 0.1 2.6 2 0 0 2 2 2 0 NACHT domain MeaB PF03308.16 ORY46466.1 - 0.039 12.9 0.6 7.4 5.5 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 ORY46466.1 - 0.048 13.2 0.1 1.1 8.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 ORY46466.1 - 0.067 12.4 0.0 0.53 9.5 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain Sigma54_activat PF00158.26 ORY46466.1 - 0.098 12.4 0.0 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.22 ORY46466.1 - 0.13 12.6 0.2 31 5.0 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AIG1 PF04548.16 ORY46466.1 - 0.16 11.2 2.8 2.5 7.4 0.2 2.6 2 0 0 2 2 2 0 AIG1 family ATP_bind_1 PF03029.17 ORY46466.1 - 0.3 10.8 1.9 9.9 5.9 0.1 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_ATPase PF09818.9 ORY46466.1 - 0.36 9.6 2.6 0.29 9.9 0.2 2.0 3 0 0 3 3 3 0 Predicted ATPase of the ABC class DUF412 PF04217.13 ORY46466.1 - 2.2 8.2 5.8 3.2 7.7 2.2 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF412 SNF2_N PF00176.23 ORY46468.1 - 6.3e-43 146.8 0.2 2.3e-42 145.0 0.2 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY46468.1 - 4.4e-11 43.1 0.0 1.2e-09 38.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY46468.1 - 3.4e-07 30.4 0.0 7.8e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY46468.1 - 1.5e-06 28.1 0.0 3.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 ORY46468.1 - 0.0055 15.6 0.1 0.017 14.1 0.1 1.7 1 1 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 zf-Nse PF11789.8 ORY46468.1 - 0.02 14.7 3.6 0.02 14.7 3.6 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RhoGAP PF00620.27 ORY46469.1 - 1.3e-36 125.7 0.0 1.7e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain Sec23_trunk PF04811.15 ORY46471.1 - 9.7e-55 185.8 0.1 1.2e-46 159.3 0.1 2.3 1 1 1 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 ORY46471.1 - 5.7e-22 77.5 0.1 1.4e-21 76.2 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 ORY46471.1 - 2.5e-19 69.8 0.0 4.4e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 ORY46471.1 - 1.1e-15 57.4 4.8 2.3e-15 56.4 4.8 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 ORY46471.1 - 8e-05 22.5 0.1 0.00027 20.8 0.1 1.9 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 ORY46471.1 - 0.0042 16.5 0.1 0.0097 15.3 0.1 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RanBP PF00641.18 ORY46472.1 - 3.5e-20 71.0 28.9 5.1e-09 35.3 4.7 4.3 4 0 0 4 4 4 4 Zn-finger in Ran binding protein and others NUP50 PF08911.11 ORY46472.1 - 1.1e-12 48.4 1.2 1.1e-12 48.4 1.2 7.9 7 3 0 7 7 7 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 ORY46472.1 - 7.5e-11 42.3 0.0 1.5e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Stc1 PF12898.7 ORY46472.1 - 0.0067 16.9 4.6 0.75 10.4 0.2 3.3 3 0 0 3 3 3 2 Stc1 domain zf-Sec23_Sec24 PF04810.15 ORY46472.1 - 0.084 12.9 6.2 8.1 6.6 0.1 4.2 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 ORY46472.1 - 2.5 7.6 14.0 24 4.4 1.1 4.4 4 0 0 4 4 4 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain RED_N PF07808.13 ORY46473.1 - 4.6e-49 167.1 0.6 4.6e-49 167.1 0.6 2.9 2 2 1 3 3 3 1 RED-like protein N-terminal region RED_C PF07807.11 ORY46473.1 - 1.3e-19 70.7 12.2 1.3e-19 70.7 12.2 3.6 4 0 0 4 4 4 1 RED-like protein C-terminal region OST-HTH PF12872.7 ORY46473.1 - 0.11 12.3 0.0 0.41 10.5 0.0 2.0 1 0 0 1 1 1 0 OST-HTH/LOTUS domain Raco_middle PF17651.1 ORY46473.1 - 0.11 12.2 0.0 0.32 10.6 0.0 1.7 1 1 0 1 1 1 0 RACo middle region AAA PF00004.29 ORY46474.1 - 1.3e-12 48.3 0.0 1.1e-11 45.3 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY46474.1 - 3.5e-05 24.1 0.3 0.0012 19.1 0.7 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY46474.1 - 0.00089 19.7 0.2 0.0045 17.4 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain Myc_N PF01056.18 ORY46474.1 - 0.001 19.1 5.5 0.0016 18.5 5.5 1.2 1 0 0 1 1 1 1 Myc amino-terminal region DUF4611 PF15387.6 ORY46474.1 - 0.031 14.5 2.1 0.07 13.3 2.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) AAA_5 PF07728.14 ORY46474.1 - 0.049 13.6 0.0 0.17 11.9 0.0 1.9 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ORY46474.1 - 0.089 13.3 0.1 0.31 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ORY46474.1 - 0.096 12.8 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 ORY46474.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Pox_Ag35 PF03286.14 ORY46474.1 - 0.17 11.7 7.5 1.7 8.4 6.2 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein adh_short PF00106.25 ORY46475.1 - 2.2e-35 121.9 0.0 3e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY46475.1 - 3.6e-21 75.8 0.0 5.4e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY46475.1 - 0.00013 21.9 0.0 0.00042 20.3 0.0 1.8 1 1 0 1 1 1 1 KR domain CH_2 PF06294.11 ORY46476.1 - 8.6e-27 93.1 0.1 1.1e-26 92.7 0.1 1.2 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 ORY46476.1 - 1.1e-07 31.6 0.0 1.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain Formyl_trans_N PF00551.19 ORY46477.1 - 3.4e-31 108.4 0.1 3.9e-31 108.2 0.1 1.0 1 0 0 1 1 1 1 Formyl transferase BCAS2 PF05700.11 ORY46478.1 - 3.2e-43 147.8 0.4 4e-43 147.5 0.4 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) XkdW PF09636.10 ORY46478.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 XkdW protein DUF4177 PF13783.6 ORY46482.1 - 0.18 12.1 0.0 0.29 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) SAM_PNT PF02198.16 ORY46484.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Acyl-CoA_dh_1 PF00441.24 ORY46485.1 - 3.7e-37 127.8 0.5 5.2e-37 127.4 0.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 ORY46485.1 - 4.4e-19 68.4 0.0 1.7e-18 66.5 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 ORY46485.1 - 1.1e-15 57.6 0.1 4.7e-14 52.4 0.1 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORY46485.1 - 2e-10 41.3 0.0 5.5e-10 39.9 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY46485.1 - 2.4e-05 24.6 0.0 3.8e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain YlmH_RBD PF17774.1 ORY46485.1 - 0.1 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative RNA-binding domain in YlmH Ephrin_rec_like PF07699.13 ORY46486.1 - 0.0014 18.4 7.4 0.0014 18.4 7.4 1.8 2 0 0 2 2 2 1 Putative ephrin-receptor like NCD3G PF07562.14 ORY46486.1 - 0.0031 17.4 7.2 0.0055 16.6 7.2 1.4 1 0 0 1 1 1 1 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 ORY46486.1 - 0.0091 16.4 1.3 0.0091 16.4 1.3 2.1 1 1 1 2 2 2 2 TNFR/NGFR cysteine-rich region OpuAC PF04069.12 ORY46486.1 - 0.021 14.4 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system Acetyltransf_1 PF00583.25 ORY46488.1 - 0.00015 21.9 0.4 0.0028 17.9 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY46488.1 - 0.0033 17.3 0.4 1.4 8.8 0.0 2.1 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY46488.1 - 0.0045 17.4 0.4 0.11 13.0 0.4 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Rubredoxin_C PF18267.1 ORY46488.1 - 0.037 14.0 0.1 0.085 12.8 0.1 1.6 1 0 0 1 1 1 0 Rubredoxin NAD+ reductase C-terminal domain DUF2370 PF10176.9 ORY46489.1 - 2.3e-33 115.7 1.5 1.2e-31 110.1 0.2 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF2370) TMEM171 PF15471.6 ORY46489.1 - 0.34 9.8 0.0 0.34 9.8 0.0 2.4 3 0 0 3 3 3 0 Transmembrane protein family 171 Herpes_pp85 PF04637.12 ORY46489.1 - 7 4.9 5.2 10 4.4 5.2 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Pkinase_Tyr PF07714.17 ORY46490.1 - 4e-39 134.4 0.0 1.5e-22 80.2 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 ORY46490.1 - 1.9e-28 99.6 0.0 1.4e-27 96.7 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Proteasome PF00227.26 ORY46491.1 - 1.3e-58 197.7 0.1 2e-58 197.1 0.1 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 ORY46491.1 - 1.4e-10 40.6 0.1 5.2e-10 38.8 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DEAD PF00270.29 ORY46492.1 - 7.7e-47 159.3 0.0 2.2e-46 157.8 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY46492.1 - 4.4e-30 104.3 0.0 4e-29 101.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY46492.1 - 0.049 13.6 0.0 0.17 11.9 0.0 1.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Sel1 PF08238.12 ORY46493.1 - 7.4e-08 32.8 2.5 0.00081 20.0 0.0 4.2 4 0 0 4 4 4 3 Sel1 repeat Ras PF00071.22 ORY46494.1 - 9.4e-55 184.6 0.0 1.1e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY46494.1 - 8e-21 74.5 0.0 1.2e-20 73.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY46494.1 - 2e-08 33.9 0.0 3.1e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 ORY46494.1 - 0.00086 18.8 0.0 0.0013 18.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 ORY46494.1 - 0.04 13.1 0.0 0.47 9.6 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain Ras PF00071.22 ORY46495.1 - 6.2e-48 162.5 0.0 7.2e-48 162.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY46495.1 - 5.1e-19 68.7 0.0 7e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY46495.1 - 0.00018 21.0 0.0 0.00028 20.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Cyclophil_like2 PF18050.1 ORY46495.1 - 0.09 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Cyclophilin-like family Ras PF00071.22 ORY46496.1 - 6e-23 81.2 0.0 8.9e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY46496.1 - 2.1e-10 40.9 0.0 3e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Glyco_hydro_47 PF01532.20 ORY46497.1 - 9.4e-102 341.3 0.0 1.2e-101 340.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_47 PF01532.20 ORY46498.1 - 4e-92 309.5 0.0 3.5e-61 207.5 0.1 2.2 2 1 0 2 2 2 2 Glycosyl hydrolase family 47 FAD_binding_3 PF01494.19 ORY46499.1 - 0.00068 19.0 0.9 0.0011 18.3 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 ORY46499.1 - 0.003 17.7 0.1 0.0078 16.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 ORY46499.1 - 0.017 14.4 2.8 0.25 10.6 0.2 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Rad10 PF03834.14 ORY46500.1 - 6.7e-48 161.4 0.4 4.5e-47 158.8 0.1 1.9 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 ORY46500.1 - 1e-07 32.4 0.0 2.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 ORY46500.1 - 0.086 12.7 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_2 PF12826.7 ORY46500.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif OpuAC PF04069.12 ORY46501.1 - 1.2e-06 28.3 0.1 1.8e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system DUF1035 PF06281.12 ORY46502.1 - 0.02 14.9 0.1 0.063 13.3 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) ADD_DNMT3 PF17980.1 ORY46502.1 - 1.9 8.5 6.1 4.6 7.3 6.1 1.6 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 ATE_N PF04376.13 ORY46503.1 - 7.9e-25 87.1 0.3 7.9e-25 87.1 0.3 1.7 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus ATE_C PF04377.15 ORY46504.1 - 2.1e-18 67.3 1.1 2.9e-18 66.8 1.1 1.2 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus Aldo_ket_red PF00248.21 ORY46510.1 - 1.6e-71 241.0 0.0 1.8e-71 240.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PH PF00169.29 ORY46512.1 - 3.5e-05 24.3 0.0 8.5e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 ORY46512.1 - 0.067 13.6 0.0 0.47 10.9 0.0 2.2 2 1 0 2 2 2 0 Pleckstrin homology domain MFS_1 PF07690.16 ORY46513.1 - 5.4e-48 163.7 47.7 5.4e-48 163.7 47.7 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY46513.1 - 3.8e-12 45.4 28.8 5e-12 45.0 28.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY46513.1 - 9.2e-10 38.0 13.2 9.2e-10 38.0 13.2 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter Pox_A14 PF05767.12 ORY46513.1 - 1.5 9.0 7.8 0.12 12.6 0.5 2.9 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Helicase_C PF00271.31 ORY46515.1 - 2.4e-09 37.5 0.9 1.3e-06 28.7 0.1 3.0 2 1 1 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 ORY46515.1 - 0.012 15.4 0.2 0.027 14.2 0.1 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase DUF3449 PF11931.8 ORY46516.1 - 7.7e-76 254.0 1.1 7.7e-76 254.0 1.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.8 ORY46516.1 - 1e-11 44.5 0.6 2.5e-11 43.3 0.6 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain SF3A3 PF16837.5 ORY46516.1 - 4.8e-07 30.2 0.1 1.5e-06 28.6 0.1 1.9 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 CHZ PF09649.10 ORY46516.1 - 0.046 13.2 0.4 0.13 11.7 0.4 1.9 1 0 0 1 1 1 0 Histone chaperone domain CHZ Methyltransf_10 PF05971.12 ORY46517.1 - 2.6e-56 191.1 0.1 1.4e-54 185.5 0.1 2.0 1 1 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 ORY46517.1 - 0.00089 18.8 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 ORY46517.1 - 0.0079 15.6 0.0 0.01 15.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 ORY46517.1 - 0.022 14.5 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 ORY46517.1 - 0.073 12.9 0.0 0.099 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 ORY46517.1 - 0.15 11.7 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Got1 PF04178.12 ORY46518.1 - 3.9e-32 111.0 11.5 4.3e-32 110.9 11.5 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family ST7 PF04184.12 ORY46518.1 - 0.046 12.2 5.4 0.048 12.1 5.4 1.0 1 0 0 1 1 1 0 ST7 protein DUF5090 PF17009.5 ORY46518.1 - 3 7.7 8.8 3.6 7.5 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) PMT_4TMC PF16192.5 ORY46519.1 - 6.6e-51 172.7 3.6 6.6e-51 172.7 3.6 3.3 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase PMT PF02366.18 ORY46519.1 - 2.4e-38 132.1 14.6 1.1e-25 90.6 10.7 2.6 1 1 1 2 2 2 2 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.19 ORY46519.1 - 5.4e-14 52.4 0.2 5.7e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 MIR domain Proteasome PF00227.26 ORY46520.1 - 2e-62 210.1 0.1 2.7e-62 209.7 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORY46520.1 - 8.1e-14 51.0 0.1 1.7e-13 49.9 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature AAA PF00004.29 ORY46521.1 - 1.4e-41 142.0 0.0 2.5e-41 141.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY46521.1 - 2e-05 24.6 0.0 7.1e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY46521.1 - 5.5e-05 23.4 0.0 0.0041 17.4 0.0 2.5 2 1 1 3 3 2 1 AAA domain AAA_16 PF13191.6 ORY46521.1 - 7.2e-05 23.2 0.1 0.002 18.5 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 ORY46521.1 - 0.00029 21.0 0.0 0.00064 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 ORY46521.1 - 0.00031 20.0 0.0 0.0006 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 ORY46521.1 - 0.0026 17.5 0.0 0.005 16.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 ORY46521.1 - 0.0067 16.2 0.1 0.1 12.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 ORY46521.1 - 0.0078 15.8 0.0 0.02 14.4 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 ORY46521.1 - 0.013 15.8 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORY46521.1 - 0.018 15.2 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ORY46521.1 - 0.027 14.4 0.0 5.3 6.9 0.0 2.5 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_3 PF07726.11 ORY46521.1 - 0.029 14.3 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORY46521.1 - 0.032 14.6 0.0 0.079 13.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 ORY46521.1 - 0.044 13.0 0.0 0.077 12.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 ORY46521.1 - 0.05 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 ORY46521.1 - 0.063 13.8 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 ORY46521.1 - 0.066 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.26 ORY46521.1 - 0.07 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 ORY46521.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 ORY46521.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NuA4 PF09340.10 ORY46522.1 - 1.4e-23 82.6 0.0 1.8e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 ATP-synt_ab PF00006.25 ORY46523.1 - 8.8e-107 355.6 0.0 1.7e-106 354.6 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 ORY46523.1 - 1.5e-27 95.9 0.5 6.3e-26 90.6 0.5 2.5 1 1 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 ORY46523.1 - 8.8e-09 35.8 0.3 2.3e-08 34.4 0.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Mac PF12464.8 ORY46523.1 - 0.014 15.6 0.1 0.03 14.6 0.1 1.6 1 0 0 1 1 1 0 Maltose acetyltransferase ThiC-associated PF13667.6 ORY46525.1 - 0.066 13.0 0.1 0.09 12.6 0.1 1.2 1 0 0 1 1 1 0 ThiC-associated domain F-box PF00646.33 ORY46528.1 - 0.041 13.8 0.1 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 F-box domain Bestrophin PF01062.21 ORY46529.1 - 3.9e-42 144.7 0.2 3.9e-42 144.7 0.2 1.6 2 0 0 2 2 2 1 Bestrophin, RFP-TM, chloride channel DUF1295 PF06966.12 ORY46529.1 - 0.031 13.8 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Tom6 PF17112.5 ORY46529.1 - 0.082 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom6, fungal DUF4390 PF14334.6 ORY46529.1 - 0.15 11.4 0.1 0.33 10.4 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4390) ATPgrasp_YheCD PF14398.6 ORY46531.1 - 0.075 12.3 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 YheC/D like ATP-grasp DUF3670 PF12419.8 ORY46531.1 - 0.19 11.6 0.0 1.7 8.5 0.0 2.1 1 1 0 1 1 1 0 SNF2 Helicase protein Rrp15p PF07890.12 ORY46532.1 - 1.1e-18 67.8 14.3 1.1e-18 67.8 14.3 3.1 1 1 1 2 2 2 1 Rrp15p Rrn6 PF10214.9 ORY46532.1 - 0.42 9.1 9.9 0.47 8.9 9.9 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor CDC45 PF02724.14 ORY46532.1 - 2.8 6.1 19.9 3.4 5.8 19.9 1.3 1 0 0 1 1 1 0 CDC45-like protein TAFII28 PF04719.14 ORY46533.1 - 7e-31 106.2 0.0 1e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region SGT1 PF07093.11 ORY46533.1 - 3.9 5.8 6.8 5.1 5.4 6.8 1.1 1 0 0 1 1 1 0 SGT1 protein UPF0126 PF03458.13 ORY46534.1 - 5.4e-39 132.0 13.9 1e-19 70.2 5.2 2.3 2 0 0 2 2 2 2 UPF0126 domain DUF4536 PF15055.6 ORY46534.1 - 1.8 8.9 6.2 3.6 7.9 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) 2OG-FeII_Oxy_2 PF13532.6 ORY46535.1 - 1.9e-12 47.8 0.0 2.6e-12 47.4 0.0 1.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Nup84_Nup100 PF04121.13 ORY46535.1 - 0.067 11.3 0.1 0.083 11.0 0.1 1.0 1 0 0 1 1 1 0 Nuclear pore protein 84 / 107 DRIM PF07539.12 ORY46536.1 - 6.9e-108 361.6 10.3 2.4e-95 320.1 7.0 5.6 6 1 1 8 8 8 2 Down-regulated in metastasis MMS19_N PF14500.6 ORY46536.1 - 3.6e-05 23.5 1.4 0.042 13.4 0.0 4.1 3 1 0 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II Anticodon_1 PF08264.13 ORY46536.1 - 0.0013 18.7 0.2 0.096 12.6 0.0 3.2 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA MbeD_MobD PF04899.12 ORY46536.1 - 0.0068 16.5 0.1 0.26 11.4 0.0 3.1 2 0 0 2 2 2 1 MbeD/MobD like UME PF08064.13 ORY46536.1 - 0.22 11.5 4.0 3.7 7.5 0.2 4.7 4 1 0 4 4 4 0 UME (NUC010) domain DHHC PF01529.20 ORY46537.1 - 3.9e-23 82.0 5.5 3.9e-23 82.0 5.5 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase zf-CHCC PF10276.9 ORY46538.1 - 4e-17 62.0 1.2 6.9e-17 61.2 1.2 1.4 1 0 0 1 1 1 1 Zinc-finger domain NTF2 PF02136.20 ORY46539.1 - 6.3e-05 23.5 2.1 0.00035 21.1 2.1 2.0 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain COX4 PF02936.14 ORY46540.1 - 2.9e-27 95.4 0.4 3.8e-27 95.0 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV ATP-synt_E PF05680.12 ORY46540.1 - 0.0034 17.7 0.0 0.0092 16.3 0.0 1.8 1 0 0 1 1 1 1 ATP synthase E chain EbsA PF17255.2 ORY46540.1 - 0.2 12.0 0.0 0.34 11.2 0.0 1.3 1 0 0 1 1 1 0 EbsA-like protein DUF1289 PF06945.13 ORY46540.1 - 0.3 10.9 1.6 5.1 7.0 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1289) Ribosomal_L27e PF01777.18 ORY46541.1 - 3.5e-17 62.5 1.0 5.9e-17 61.8 1.0 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 ORY46541.1 - 2.9e-06 27.0 0.2 6.2e-06 26.0 0.2 1.5 1 0 0 1 1 1 1 KOW motif DEC-1_C PF04626.13 ORY46541.1 - 0.11 12.9 0.6 0.17 12.3 0.4 1.3 1 1 0 1 1 1 0 Dec-1 protein, C terminal region IMS PF00817.20 ORY46542.1 - 4.7e-35 120.8 0.0 8.7e-34 116.7 0.0 2.4 1 1 0 1 1 1 1 impB/mucB/samB family zf_UBZ PF18439.1 ORY46542.1 - 2.1e-08 33.6 2.8 4.9e-08 32.4 2.8 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 ORY46542.1 - 0.0012 19.1 0.1 0.0034 17.6 0.1 1.8 1 0 0 1 1 1 1 IMS family HHH motif CpXC PF14353.6 ORY46542.1 - 0.032 14.3 0.1 0.072 13.1 0.1 1.5 1 0 0 1 1 1 0 CpXC protein c-SKI_SMAD_bind PF08782.10 ORY46542.1 - 0.036 14.3 0.2 0.084 13.1 0.2 1.6 1 0 0 1 1 1 0 c-SKI Smad4 binding domain Cyclin_N PF00134.23 ORY46544.1 - 6.4e-33 113.2 0.5 7.8e-32 109.7 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 ORY46544.1 - 2.9e-09 37.0 0.1 1.3e-08 34.9 0.1 2.1 1 1 0 1 1 1 1 Cyclin, C-terminal domain ATPgrasp_YheCD PF14398.6 ORY46545.1 - 0.01 15.1 0.0 0.024 13.9 0.0 1.6 1 0 0 1 1 1 0 YheC/D like ATP-grasp SlyX PF04102.12 ORY46545.1 - 3.4 8.4 8.3 0.78 10.4 2.4 2.8 2 1 1 3 3 3 0 SlyX DUF4200 PF13863.6 ORY46546.1 - 5.5e-17 62.3 28.5 4.6e-16 59.3 20.5 2.5 2 1 1 3 3 3 2 Domain of unknown function (DUF4200) DUF1664 PF07889.12 ORY46546.1 - 0.00039 20.5 5.3 0.00073 19.6 5.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) HEPN_Toprim_N PF18871.1 ORY46546.1 - 0.0044 17.0 2.3 0.0062 16.5 2.3 1.2 1 0 0 1 1 1 1 HEPN/Toprim N-terminal domain 1 PXA PF02194.15 ORY46546.1 - 0.051 13.5 2.5 0.071 13.1 2.5 1.2 1 0 0 1 1 1 0 PXA domain DUF3768 PF12599.8 ORY46546.1 - 0.052 13.6 0.3 0.09 12.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3768) DUF3072 PF11272.8 ORY46546.1 - 0.074 13.0 2.1 3 7.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3072) TMPIT PF07851.13 ORY46546.1 - 0.1 11.9 7.9 0.16 11.2 7.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein ATP-synt_B PF00430.18 ORY46546.1 - 0.54 10.3 12.3 0.067 13.3 8.3 1.5 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Exonuc_VII_L PF02601.15 ORY46546.1 - 1.2 8.6 7.4 1.5 8.3 7.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit LRR_4 PF12799.7 ORY46547.1 - 0.078 13.4 8.6 0.068 13.6 3.4 3.1 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) EF-G-binding_N PF07299.11 ORY46548.1 - 0.009 16.5 0.1 0.067 13.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G-binding protein, N-terminal LRR_8 PF13855.6 ORY46549.1 - 3.5e-20 71.5 26.4 2e-09 37.0 3.7 4.3 2 1 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 ORY46549.1 - 2e-14 53.4 21.7 2.2e-05 24.7 0.7 4.6 1 1 6 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY46549.1 - 2.3e-10 39.5 15.3 0.41 11.4 0.4 6.8 7 0 0 7 7 7 4 Leucine Rich Repeat SAM_Ste50p PF09235.10 ORY46549.1 - 0.26 11.5 1.3 17 5.7 0.1 3.4 3 1 1 4 4 4 0 Ste50p, sterile alpha motif LRR_6 PF13516.6 ORY46549.1 - 1.1 9.5 18.2 16 5.9 0.2 6.6 8 0 0 8 8 8 0 Leucine Rich repeat SGL PF08450.12 ORY46550.1 - 4.9e-09 36.1 0.0 7.6e-09 35.5 0.0 1.3 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 ORY46550.1 - 0.0029 17.7 0.0 0.013 15.6 0.0 2.1 2 0 0 2 2 2 1 Strictosidine synthase NHL PF01436.21 ORY46550.1 - 0.034 14.2 0.1 1.5 9.0 0.0 3.4 4 1 0 4 4 4 0 NHL repeat LRR_8 PF13855.6 ORY46551.1 - 1e-19 70.1 17.8 1.9e-09 37.1 2.0 4.8 2 1 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 ORY46551.1 - 1.7e-12 47.3 20.0 0.00076 19.8 2.3 5.8 1 1 7 8 8 8 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY46551.1 - 1.8e-05 24.7 21.3 1.8 9.4 0.3 8.4 8 1 1 9 9 9 2 Leucine Rich Repeat F-box-like PF12937.7 ORY46551.1 - 0.011 15.6 1.6 0.03 14.2 1.6 1.8 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 ORY46551.1 - 0.012 15.5 0.4 0.029 14.3 0.4 1.7 1 0 0 1 1 1 0 F-box domain LRR_6 PF13516.6 ORY46551.1 - 0.85 9.8 9.8 25 5.2 0.1 5.5 5 0 0 5 5 5 0 Leucine Rich repeat MitMem_reg PF13012.6 ORY46552.1 - 5.7e-39 133.0 1.2 8.1e-39 132.5 1.2 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 ORY46552.1 - 6.6e-05 22.9 0.0 0.00019 21.4 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF3839 PF12943.7 ORY46552.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3839) UCH PF00443.29 ORY46553.1 - 5.7e-44 150.5 1.4 7.6e-44 150.1 1.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY46553.1 - 5.3e-07 29.5 1.1 3.6e-06 26.8 1.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Qua1 PF16274.5 ORY46553.1 - 0.022 14.6 0.1 1.4 8.8 0.1 2.5 2 0 0 2 2 2 0 Qua1 domain KIP1 PF07765.12 ORY46553.1 - 0.094 12.8 0.6 0.29 11.3 0.0 2.1 2 0 0 2 2 2 0 KIP1-like protein DKCLD PF08068.12 ORY46554.1 - 0.099 12.7 0.1 0.22 11.6 0.0 1.7 1 1 0 1 1 1 0 DKCLD (NUC011) domain zf-MYND PF01753.18 ORY46555.1 - 1.7e-09 37.6 9.3 3.1e-09 36.8 9.3 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 ORY46555.1 - 0.16 12.1 7.6 6.5 6.9 7.6 2.3 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 PTCB-BRCT PF12738.7 ORY46556.1 - 2.8e-06 27.2 0.0 6.1e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 ORY46556.1 - 0.00016 22.0 1.1 0.00064 20.0 0.1 2.5 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 ORY46556.1 - 0.0025 18.2 0.1 0.0086 16.5 0.1 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 ORY46556.1 - 0.0054 17.0 0.4 0.016 15.5 0.4 1.8 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 ORY46556.1 - 0.071 13.2 0.0 0.38 10.9 0.1 2.2 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain DUF3482 PF11981.8 ORY46556.1 - 0.27 10.6 0.4 0.59 9.5 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) WLM PF08325.10 ORY46557.1 - 1.7e-33 116.3 0.1 2.9e-33 115.6 0.1 1.4 1 0 0 1 1 1 1 WLM domain ubiquitin PF00240.23 ORY46557.1 - 0.0014 18.3 0.0 0.0036 17.0 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 ORY46557.1 - 0.0069 16.8 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain SprT-like PF10263.9 ORY46557.1 - 0.25 11.2 1.5 0.4 10.6 1.5 1.4 1 1 0 1 1 1 0 SprT-like family DUF45 PF01863.17 ORY46557.1 - 0.66 10.0 6.2 0.43 10.6 4.1 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF45 MMR_HSR1 PF01926.23 ORY46560.1 - 5.7e-05 23.2 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY46560.1 - 0.00044 20.7 0.2 0.0015 18.9 0.1 2.0 1 1 1 2 2 2 1 AAA ATPase domain Septin PF00735.18 ORY46560.1 - 0.00062 19.1 0.5 0.0048 16.2 0.0 2.6 2 2 1 3 3 3 1 Septin Dynamin_N PF00350.23 ORY46560.1 - 0.0013 18.8 0.3 0.0087 16.1 0.2 2.1 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 ORY46560.1 - 0.0013 18.6 0.1 0.0033 17.4 0.1 1.7 1 1 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 ORY46560.1 - 0.0023 17.3 0.1 0.0092 15.3 0.0 1.9 1 1 1 2 2 2 1 AIG1 family IIGP PF05049.13 ORY46560.1 - 0.0047 16.0 0.9 0.0086 15.2 0.1 1.8 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) MeaB PF03308.16 ORY46560.1 - 0.039 12.9 0.8 0.056 12.4 0.8 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 ORY46560.1 - 0.052 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.12 ORY46560.1 - 0.087 12.1 0.2 0.16 11.2 0.1 1.5 1 1 0 1 1 1 0 Zeta toxin Guanylate_kin PF00625.21 ORY46560.1 - 0.1 12.3 0.0 0.26 10.9 0.0 1.8 1 1 0 1 1 1 0 Guanylate kinase YebO PF13974.6 ORY46560.1 - 0.1 12.7 0.5 0.1 12.7 0.5 2.0 2 0 0 2 2 2 0 YebO-like protein LRR_8 PF13855.6 ORY46561.1 - 2e-14 53.0 5.3 2.4e-08 33.6 5.0 3.0 2 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY46561.1 - 4.3e-11 42.9 9.9 3.6e-05 24.0 5.6 3.9 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY46561.1 - 5.5e-09 35.4 10.4 0.99 9.6 0.2 5.7 5 0 0 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 ORY46561.1 - 1.4e-07 31.1 12.6 5.3 8.0 0.0 6.6 7 1 0 7 7 7 4 Leucine Rich Repeat F-box-like PF12937.7 ORY46561.1 - 0.044 13.7 0.6 0.13 12.1 0.6 1.8 1 0 0 1 1 1 0 F-box-like Ribonuc_red_sm PF00268.21 ORY46562.1 - 1.2e-13 51.2 1.1 2.9e-09 36.8 0.3 2.4 2 1 1 3 3 3 2 Ribonucleotide reductase, small chain AalphaY_MDB PF04611.12 ORY46564.1 - 0.052 13.6 0.1 0.078 13.0 0.1 1.3 1 0 0 1 1 1 0 Mating type protein A alpha Y mating type dependent binding region ABC_tran PF00005.27 ORY46566.1 - 2.1e-06 28.3 0.0 3.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ORY46566.1 - 0.00022 20.8 0.2 0.00029 20.4 0.2 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain LRR_4 PF12799.7 ORY46567.1 - 4.1e-15 55.6 9.9 0.0008 19.8 0.0 5.4 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY46567.1 - 4.6e-11 42.3 13.3 1.5e-05 24.6 1.8 5.2 1 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 ORY46567.1 - 1.2e-06 28.3 14.1 1.3 9.9 0.1 7.7 8 2 0 8 8 8 2 Leucine Rich Repeat F-box PF00646.33 ORY46567.1 - 2.3e-06 27.3 0.6 6.9e-06 25.8 0.6 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY46567.1 - 0.051 13.5 0.6 0.13 12.2 0.6 1.7 1 0 0 1 1 1 0 F-box-like F-box-like_2 PF13013.6 ORY46567.1 - 0.06 13.3 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 F-box-like domain LRR_6 PF13516.6 ORY46567.1 - 0.068 13.2 16.4 3.6 7.9 0.3 6.1 7 0 0 7 7 7 0 Leucine Rich repeat LRR_8 PF13855.6 ORY46568.1 - 5.2e-14 51.8 11.1 3.7e-07 29.8 0.4 3.1 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY46568.1 - 6.7e-14 51.8 25.8 0.00025 21.3 0.2 4.3 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY46568.1 - 2.2e-09 36.6 14.6 0.56 11.0 0.2 7.0 6 1 0 6 6 6 5 Leucine Rich Repeat LRR_6 PF13516.6 ORY46568.1 - 3.5e-06 26.6 17.1 2.2 8.5 0.1 6.8 7 0 0 7 7 7 4 Leucine Rich repeat PRK PF00485.18 ORY46569.1 - 9.7e-55 185.4 0.3 2.4e-54 184.1 0.0 1.8 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 ORY46569.1 - 2.4e-24 86.0 0.8 6.1e-20 71.6 0.2 2.3 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase AAA_18 PF13238.6 ORY46569.1 - 6.3e-05 23.5 0.0 0.00025 21.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain CPT PF07931.12 ORY46569.1 - 0.00014 21.8 0.1 0.00035 20.5 0.0 1.7 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.6 ORY46569.1 - 0.00025 21.5 1.3 1.2 9.6 0.1 3.2 3 0 0 3 3 3 2 AAA domain CoaE PF01121.20 ORY46569.1 - 0.0012 18.5 0.1 0.15 11.7 0.1 2.4 2 0 0 2 2 2 1 Dephospho-CoA kinase Zeta_toxin PF06414.12 ORY46569.1 - 0.0027 17.0 0.0 0.0055 16.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 ORY46569.1 - 0.0082 16.3 0.1 0.034 14.3 0.0 2.2 3 1 0 3 3 3 1 AAA domain Cytidylate_kin PF02224.18 ORY46569.1 - 0.014 15.1 0.1 0.17 11.6 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase dNK PF01712.19 ORY46569.1 - 0.087 12.7 0.1 0.52 10.1 0.1 2.3 1 1 1 2 2 2 0 Deoxynucleoside kinase Peripla_BP_6 PF13458.6 ORY46569.1 - 0.19 11.4 0.0 3.7 7.1 0.0 2.5 3 0 0 3 3 3 0 Periplasmic binding protein L_HMGIC_fpl PF10242.9 ORY46570.1 - 0.027 14.7 0.6 0.042 14.1 0.1 1.5 2 0 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein Phage_holin_2_3 PF16080.5 ORY46570.1 - 6.6 6.6 6.3 10 6.0 3.0 2.5 2 0 0 2 2 2 0 Bacteriophage holin family HP1 DHHC PF01529.20 ORY46571.1 - 1.4e-35 122.3 5.0 2.1e-35 121.7 5.0 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Colicin_V PF02674.16 ORY46571.1 - 0.0012 18.9 0.6 0.0017 18.3 0.6 1.2 1 0 0 1 1 1 1 Colicin V production protein Ac76 PF05814.11 ORY46571.1 - 0.032 14.2 0.4 0.055 13.5 0.4 1.3 1 0 0 1 1 1 0 Orf76 (Ac76) DNA_pol_B_exo1 PF03104.19 ORY46572.1 - 1.6e-08 34.1 0.0 3.4e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 ORY46574.1 - 4.1e-75 253.2 0.1 1.2e-74 251.7 0.1 1.7 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 ORY46574.1 - 7.9e-10 38.4 0.3 5.2e-09 35.7 0.1 2.0 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 ORY46574.1 - 1.9e-07 31.5 5.7 4.4e-07 30.3 5.7 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta PHD PF00628.29 ORY46574.1 - 0.85 9.6 4.5 2.2 8.3 4.5 1.8 1 1 0 1 1 1 0 PHD-finger T3SS_needle_E PF08988.10 ORY46578.1 - 0.073 13.2 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle TAF6_C PF07571.13 ORY46579.1 - 6.3e-27 93.7 0.0 4.5e-26 91.0 0.0 2.3 2 1 0 3 3 3 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 ORY46579.1 - 2.3e-20 72.5 0.1 2.1e-19 69.5 0.1 2.4 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 ORY46579.1 - 0.00059 20.2 0.2 0.0011 19.4 0.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 U3snoRNP10 PF12397.8 ORY46579.1 - 0.0062 16.9 0.0 0.031 14.6 0.0 2.2 1 1 1 2 2 2 1 U3 small nucleolar RNA-associated protein 10 ANF_receptor PF01094.28 ORY46580.1 - 7.8e-05 21.9 0.0 8.8e-05 21.8 0.0 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 ORY46581.1 - 2.6e-07 30.6 8.8 3.4e-07 30.2 8.8 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR HisKA_7TM PF16927.5 ORY46581.1 - 0.0029 17.7 6.0 0.0043 17.1 6.0 1.2 1 0 0 1 1 1 1 N-terminal 7TM region of histidine kinase Sulfotransfer_4 PF17784.1 ORY46581.1 - 0.027 14.3 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase domain ANF_receptor PF01094.28 ORY46582.1 - 2.8e-24 85.9 0.0 3.7e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY46582.1 - 0.00031 20.5 0.0 0.00038 20.2 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Stig1 PF04885.13 ORY46584.1 - 3.6e-07 30.8 16.9 4.1e-07 30.6 16.9 1.3 1 0 0 1 1 1 1 Stigma-specific protein, Stig1 Fer4 PF00037.27 ORY46584.1 - 2.2 8.3 12.9 0.79 9.6 2.1 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Polysacc_deac_1 PF01522.21 ORY46585.1 - 8e-18 64.5 0.0 9.6e-18 64.3 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORY46585.1 - 0.00013 21.3 0.0 0.00016 21.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2334 PF10096.9 ORY46585.1 - 0.0034 17.1 0.1 0.0061 16.2 0.1 1.3 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Ras PF00071.22 ORY46586.1 - 1.6e-41 141.6 1.0 1.1e-39 135.6 1.0 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 ORY46586.1 - 5.6e-20 71.8 0.2 7.6e-18 64.9 0.2 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY46586.1 - 4.3e-05 23.0 0.1 0.00021 20.8 0.1 1.9 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 ORY46586.1 - 0.0002 21.3 0.2 0.27 11.1 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase ABC_tran PF00005.27 ORY46586.1 - 0.032 14.7 0.0 0.043 14.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 ORY46586.1 - 0.16 12.1 0.1 4.7 7.3 0.0 2.2 1 1 1 2 2 2 0 50S ribosome-binding GTPase Pkinase PF00069.25 ORY46587.1 - 1.4e-72 244.2 0.0 1.7e-72 244.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY46587.1 - 8.1e-33 113.8 0.0 9.7e-33 113.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY46587.1 - 9.6e-07 28.4 0.0 2.3e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY46587.1 - 2.4e-06 26.6 0.0 4.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY46587.1 - 0.0011 18.9 0.0 0.01 15.8 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY46587.1 - 0.039 13.3 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 ORY46588.1 - 2e-75 253.6 0.0 2.3e-75 253.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY46588.1 - 1.3e-30 106.6 0.0 1.5e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY46588.1 - 8e-09 35.2 0.0 9.1e-08 31.8 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORY46588.1 - 6.6e-07 28.4 0.0 1.1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORY46588.1 - 0.0015 18.0 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY46588.1 - 0.17 11.8 0.0 0.56 10.1 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family CaMKII_AD PF08332.10 ORY46590.1 - 1.1e-11 45.0 1.1 3.7e-09 36.8 0.0 2.2 1 1 1 2 2 2 2 Calcium/calmodulin dependent protein kinase II association domain SnoaL_3 PF13474.6 ORY46590.1 - 0.0039 17.5 0.1 0.0092 16.2 0.0 1.6 2 0 0 2 2 2 1 SnoaL-like domain Meleagrin PF08189.11 ORY46590.1 - 0.089 12.5 0.3 0.15 11.8 0.3 1.4 1 0 0 1 1 1 0 Meleagrin/Cygnin family Staph_haemo PF05480.11 ORY46590.1 - 0.11 12.3 0.9 0.16 11.8 0.1 1.6 2 0 0 2 2 2 0 Staphylococcus haemolytic protein Glyco_trans_2_3 PF13632.6 ORY46591.1 - 0.078 12.9 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Glycosyl transferase family group 2 PT-VENN PF04829.13 ORY46591.1 - 0.37 10.9 4.1 1.1 9.3 0.8 2.4 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif SGL PF08450.12 ORY46592.1 - 0.00068 19.3 0.0 0.23 11.0 0.0 2.2 2 0 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region Mito_carr PF00153.27 ORY46593.1 - 6.1e-12 45.3 1.4 9.3e-06 25.5 0.0 3.9 3 1 1 4 4 4 3 Mitochondrial carrier protein ANF_receptor PF01094.28 ORY46594.1 - 9.4e-05 21.7 0.1 0.00011 21.4 0.1 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 ORY46595.1 - 1.4e-14 54.4 33.3 2.1e-14 53.9 33.3 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF4203 PF13886.6 ORY46596.1 - 2.9e-13 50.0 21.9 3.2e-08 33.5 12.3 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4203) CbiQ PF02361.16 ORY46596.1 - 5.4 6.6 9.4 0.69 9.5 5.2 1.7 2 0 0 2 2 2 0 Cobalt transport protein Ank_2 PF12796.7 ORY46597.1 - 2.5e-12 47.2 0.7 0.014 15.9 0.0 3.5 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY46597.1 - 1.2e-09 38.4 1.5 0.3 11.7 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY46597.1 - 1.7e-07 31.0 2.9 0.34 11.6 0.0 6.4 7 0 0 7 7 7 2 Ankyrin repeat Ank PF00023.30 ORY46597.1 - 2.5e-05 24.5 3.5 0.18 12.3 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 ORY46597.1 - 0.00022 21.4 0.4 5.1 7.5 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) PTPLA PF04387.14 ORY46598.1 - 3.9e-53 179.5 6.6 7.4e-53 178.6 6.6 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DUF1308 PF07000.11 ORY46600.1 - 1.6e-11 44.4 0.0 9.1e-11 42.0 0.0 2.0 1 1 0 2 2 2 1 Protein of unknown function (DUF1308) S-antigen PF05756.11 ORY46600.1 - 0.13 12.6 0.5 0.77 10.2 1.2 1.7 2 0 0 2 2 2 0 S-antigen protein CENP-B_dimeris PF09026.10 ORY46600.1 - 0.62 10.5 9.8 1.4 9.4 9.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF5614 PF18474.1 ORY46600.1 - 4.3 6.6 4.4 30 3.8 0.0 2.9 3 1 1 4 4 4 0 Family of unknown function (DUF5614) TLD PF07534.16 ORY46601.1 - 8.2e-28 97.4 0.2 1.6e-27 96.4 0.1 1.5 2 0 0 2 2 2 1 TLD zf-C2H2 PF00096.26 ORY46602.1 - 6.1e-08 32.7 5.8 0.0039 17.6 1.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 ORY46602.1 - 6.7e-07 29.4 7.1 0.0054 17.0 0.2 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 ORY46602.1 - 1.7e-06 28.4 7.8 0.0087 16.8 1.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ORY46602.1 - 0.00037 20.8 2.9 0.038 14.4 0.3 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type OTT_1508_deam PF14441.6 ORY46602.1 - 0.0028 17.6 1.1 0.0043 17.0 0.2 1.8 1 1 1 2 2 2 1 OTT_1508-like deaminase zf-C2H2_7 PF15269.6 ORY46602.1 - 0.012 15.6 0.1 0.012 15.6 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger zf-C2H2_6 PF13912.6 ORY46602.1 - 0.016 15.2 8.2 0.14 12.2 2.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORY46602.1 - 0.017 14.9 0.1 0.038 13.7 0.1 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 ORY46602.1 - 0.031 14.2 6.1 2.1 8.4 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 ORY46602.1 - 0.072 13.6 12.3 0.076 13.5 0.8 3.4 3 1 0 3 3 3 0 Zinc-finger double domain OrsD PF12013.8 ORY46602.1 - 0.15 12.6 1.9 2.4 8.6 0.6 2.2 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_2 PF12756.7 ORY46602.1 - 0.18 12.2 2.8 1.7 9.0 1.8 2.4 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) RNA_POL_M_15KD PF02150.16 ORY46602.1 - 0.51 10.3 0.1 0.51 10.3 0.1 2.2 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit ANF_receptor PF01094.28 ORY46603.1 - 3.2e-05 23.2 0.0 6.1e-05 22.3 0.0 1.4 2 0 0 2 2 2 1 Receptor family ligand binding region MCM PF00493.23 ORY46605.1 - 3.6e-64 215.9 0.1 2.8e-63 213.0 0.1 2.4 1 1 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 ORY46605.1 - 7.3e-17 61.6 1.1 7.3e-17 61.6 1.1 2.1 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_OB PF17207.3 ORY46605.1 - 1.1e-15 57.6 1.0 6.8e-15 55.0 1.0 2.2 1 1 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 ORY46605.1 - 2.6e-08 34.4 0.0 9.1e-08 32.6 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain MCM2_N PF12619.8 ORY46605.1 - 4.8 7.4 16.4 0.15 12.4 9.8 1.8 2 0 0 2 2 2 0 Mini-chromosome maintenance protein 2 Mito_carr PF00153.27 ORY46606.1 - 3.1e-36 123.2 7.0 2.4e-14 53.0 0.5 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 ORY46607.1 - 1e-22 79.9 8.4 1.8e-07 31.0 0.0 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein DUF4203 PF13886.6 ORY46607.1 - 0.032 13.9 0.7 0.16 11.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4203) HALZ PF02183.18 ORY46608.1 - 0.0035 17.5 2.0 0.08 13.2 0.1 2.3 2 0 0 2 2 2 1 Homeobox associated leucine zipper DivIC PF04977.15 ORY46608.1 - 0.0037 17.0 8.7 0.25 11.2 0.6 2.1 1 1 1 2 2 2 2 Septum formation initiator SprA-related PF12118.8 ORY46608.1 - 0.0062 15.7 2.1 0.0075 15.5 2.1 1.1 1 0 0 1 1 1 1 SprA-related family bZIP_2 PF07716.15 ORY46608.1 - 0.0062 16.6 5.9 0.89 9.7 0.5 2.2 2 0 0 2 2 2 2 Basic region leucine zipper Mto2_bdg PF12808.7 ORY46608.1 - 0.01 16.1 3.9 1.3 9.3 0.3 2.3 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region ADIP PF11559.8 ORY46608.1 - 0.014 15.4 7.3 0.019 15.1 7.3 1.1 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Swi5 PF07061.11 ORY46608.1 - 0.026 14.6 1.6 22 5.2 3.8 2.8 2 1 0 2 2 2 0 Swi5 Uso1_p115_C PF04871.13 ORY46608.1 - 0.029 14.7 3.2 0.039 14.3 3.2 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Allexi_40kDa PF05549.11 ORY46608.1 - 0.035 13.6 5.2 0.043 13.3 5.2 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein OmpH PF03938.14 ORY46608.1 - 0.046 14.1 1.6 0.061 13.7 1.6 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SpoIIIAH PF12685.7 ORY46608.1 - 0.074 12.9 5.7 0.089 12.6 5.7 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein HlyD_2 PF12700.7 ORY46608.1 - 0.095 11.4 1.2 0.12 11.1 1.2 1.0 1 0 0 1 1 1 0 HlyD family secretion protein CHD5 PF04420.14 ORY46608.1 - 0.099 12.5 0.4 0.15 11.9 0.4 1.3 1 0 0 1 1 1 0 CHD5-like protein DUF3450 PF11932.8 ORY46608.1 - 0.24 10.7 3.3 0.31 10.3 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) LapA_dom PF06305.11 ORY46608.1 - 0.24 11.2 1.5 8.1 6.4 0.5 2.3 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain FlaC_arch PF05377.11 ORY46608.1 - 0.25 11.7 6.3 5.5 7.5 0.7 2.3 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) GIT_CC PF16559.5 ORY46608.1 - 0.29 11.0 10.0 0.84 9.6 5.5 2.4 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cnn_1N PF07989.11 ORY46608.1 - 0.31 11.2 7.7 5.5 7.2 7.6 2.1 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF1640 PF07798.11 ORY46608.1 - 0.35 10.9 7.3 0.82 9.7 7.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) TolA_bind_tri PF16331.5 ORY46608.1 - 0.5 10.5 8.6 1.7 8.8 2.0 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation ZapB PF06005.12 ORY46608.1 - 0.65 10.5 10.0 2.2 8.8 9.5 1.9 1 1 0 1 1 1 0 Cell division protein ZapB JIP_LZII PF16471.5 ORY46608.1 - 0.71 10.1 7.1 3 8.1 0.9 2.2 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II SlyX PF04102.12 ORY46608.1 - 0.77 10.4 4.6 1.6 9.4 0.7 2.2 1 1 1 2 2 2 0 SlyX NYD-SP28_assoc PF14775.6 ORY46608.1 - 0.92 9.7 5.3 2.3 8.4 0.5 2.2 2 0 0 2 2 2 0 Sperm tail C-terminal domain TSC22 PF01166.18 ORY46608.1 - 1.4 9.2 5.1 3.5 8.0 0.5 2.3 1 1 1 2 2 2 0 TSC-22/dip/bun family TMPIT PF07851.13 ORY46608.1 - 1.6 7.9 3.2 1.9 7.6 3.2 1.0 1 0 0 1 1 1 0 TMPIT-like protein DUF4349 PF14257.6 ORY46608.1 - 1.6 8.1 5.3 2.1 7.7 4.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) Spc24 PF08286.11 ORY46608.1 - 8.5 6.7 8.8 81 3.5 8.8 2.0 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 ZnuA PF01297.17 ORY46609.1 - 0.00013 21.4 0.2 0.00013 21.4 0.2 2.4 1 1 0 2 2 2 1 Zinc-uptake complex component A periplasmic ERCC4 PF02732.15 ORY46609.1 - 0.013 15.7 0.9 0.028 14.6 0.9 1.6 1 0 0 1 1 1 0 ERCC4 domain EzrA PF06160.12 ORY46609.1 - 0.013 13.7 22.1 0.041 12.1 14.0 2.1 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA IFT57 PF10498.9 ORY46609.1 - 0.021 13.8 24.2 0.011 14.7 15.4 3.0 2 2 0 2 2 2 0 Intra-flagellar transport protein 57 T3SSipB PF16535.5 ORY46609.1 - 0.024 15.1 9.6 0.024 15.1 9.6 3.2 2 1 1 3 3 3 0 Type III cell invasion protein SipB APG17 PF04108.12 ORY46609.1 - 0.041 13.0 22.0 0.18 10.9 3.7 2.5 2 0 0 2 2 2 0 Autophagy protein Apg17 OmpH PF03938.14 ORY46609.1 - 0.043 14.2 32.5 0.16 12.3 2.7 3.3 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) YojJ PF10372.9 ORY46609.1 - 0.12 12.5 6.9 0.29 11.2 1.4 3.6 2 1 1 3 3 3 0 Bacterial membrane-spanning protein N-terminus Golgin_A5 PF09787.9 ORY46609.1 - 0.15 11.5 27.7 0.11 12.0 16.7 2.5 2 0 0 2 2 2 0 Golgin subfamily A member 5 Flagellin_C PF00700.21 ORY46609.1 - 0.26 11.7 12.1 0.048 14.0 2.1 3.5 3 2 0 3 3 2 0 Bacterial flagellin C-terminal helical region DUF1501 PF07394.12 ORY46609.1 - 0.3 10.1 9.7 0.71 8.9 5.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1501) Filament PF00038.21 ORY46609.1 - 0.72 9.4 35.7 0.56 9.7 15.5 3.1 2 1 1 3 3 3 0 Intermediate filament protein Spc7 PF08317.11 ORY46609.1 - 0.73 8.7 43.5 0.21 10.4 7.6 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein Tropomyosin PF00261.20 ORY46609.1 - 0.75 9.1 36.4 0.53 9.6 17.4 3.0 2 1 1 3 3 3 0 Tropomyosin COG2 PF06148.11 ORY46609.1 - 0.81 9.8 25.2 0.68 10.0 1.3 5.2 3 2 2 5 5 5 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 ORY46609.1 - 0.82 9.7 14.4 0.56 10.3 3.5 3.4 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) Nup88 PF10168.9 ORY46609.1 - 1 7.1 22.5 0.36 8.6 14.2 2.3 2 0 0 2 2 2 0 Nuclear pore component Occludin_ELL PF07303.13 ORY46609.1 - 1.8 9.4 16.3 8.3 7.2 4.3 4.3 2 1 2 4 4 4 0 Occludin homology domain TPR_MLP1_2 PF07926.12 ORY46609.1 - 1.8 8.6 48.3 1.1 9.3 13.7 4.5 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein ICA69 PF04629.14 ORY46609.1 - 2.5 8.4 11.8 0.4 11.0 7.2 1.9 1 1 1 2 2 2 0 Islet cell autoantigen ICA69, C-terminal domain UPF0242 PF06785.11 ORY46609.1 - 2.6 8.1 33.1 0.81 9.8 4.5 3.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Baculo_PEP_C PF04513.12 ORY46609.1 - 3.4 7.7 15.1 0.76 9.8 4.5 3.5 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FPP PF05911.11 ORY46609.1 - 3.6 5.6 32.6 2.2 6.3 3.1 2.1 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil DUF4201 PF13870.6 ORY46609.1 - 4 7.1 28.3 0.97 9.1 0.6 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4201) CALCOCO1 PF07888.11 ORY46609.1 - 4.7 5.9 39.1 0.091 11.6 11.5 2.8 1 1 1 2 2 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Mt_ATP-synt_D PF05873.12 ORY46609.1 - 5.7 6.8 13.1 0.44 10.4 1.5 2.9 2 1 1 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) ATG16 PF08614.11 ORY46609.1 - 5.8 7.1 42.8 1.8 8.8 9.8 3.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Atg14 PF10186.9 ORY46609.1 - 5.8 5.9 27.3 1.3 8.0 8.8 3.1 1 1 1 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 MscS_porin PF12795.7 ORY46609.1 - 6.1 6.3 44.9 3.8 7.0 16.7 3.4 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain AAA_31 PF13614.6 ORY46609.1 - 8 6.3 8.6 1.5 8.7 0.6 2.8 2 2 1 3 3 3 0 AAA domain KELK PF15796.5 ORY46609.1 - 8.2 7.0 26.5 1.1 9.8 7.3 4.4 2 2 2 4 4 4 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase DUF3584 PF12128.8 ORY46609.1 - 9.5 3.6 38.7 0.17 9.4 23.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Lectin_N PF03954.14 ORY46609.1 - 9.8 5.9 15.3 2.3 8.0 0.6 3.4 2 2 1 4 4 4 0 Hepatic lectin, N-terminal domain HMMR_N PF15905.5 ORY46610.1 - 0.00058 19.4 25.4 0.0038 16.7 7.0 3.0 2 1 1 3 3 3 2 Hyaluronan mediated motility receptor N-terminal AAA_13 PF13166.6 ORY46610.1 - 0.002 16.9 13.3 0.0034 16.1 13.2 1.3 1 1 0 1 1 1 1 AAA domain DUF5082 PF16888.5 ORY46610.1 - 0.014 15.6 14.5 0.21 11.9 0.5 4.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5082) Spc7 PF08317.11 ORY46610.1 - 0.018 13.9 24.6 0.24 10.2 15.7 2.8 1 1 0 2 2 2 0 Spc7 kinetochore protein Pox_A_type_inc PF04508.12 ORY46610.1 - 0.034 14.0 0.3 7.4 6.6 0.0 3.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat WD40_alt PF14077.6 ORY46610.1 - 0.054 13.4 0.1 0.054 13.4 0.1 3.2 4 0 0 4 4 2 0 Alternative WD40 repeat motif HIP1_clath_bdg PF16515.5 ORY46610.1 - 0.081 13.5 1.0 0.081 13.5 1.0 3.6 3 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SOGA PF11365.8 ORY46610.1 - 0.11 13.6 0.7 0.11 13.6 0.7 3.4 2 1 1 3 3 3 0 Protein SOGA DUF948 PF06103.11 ORY46610.1 - 0.13 12.5 9.5 1.9 8.8 1.2 3.5 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) IFT57 PF10498.9 ORY46610.1 - 0.16 10.9 12.4 0.031 13.3 7.6 1.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF4407 PF14362.6 ORY46610.1 - 0.18 11.1 11.3 2.4 7.5 11.3 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 ORY46610.1 - 0.2 11.7 19.0 2.1 8.4 3.4 3.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.7 ORY46610.1 - 0.28 11.3 21.5 2.3 8.4 0.2 3.2 2 1 0 2 2 2 0 Tropomyosin like Spidroin_MaSp PF11260.8 ORY46610.1 - 0.3 11.4 9.8 0.55 10.6 2.2 2.8 2 1 0 2 2 2 0 Major ampullate spidroin 1 and 2 Filament PF00038.21 ORY46610.1 - 0.46 10.0 20.2 0.77 9.3 6.0 3.0 1 1 1 3 3 3 0 Intermediate filament protein Fez1 PF06818.15 ORY46610.1 - 0.49 10.8 18.5 4.6 7.6 6.9 3.0 1 1 2 3 3 3 0 Fez1 NPV_P10 PF05531.12 ORY46610.1 - 0.77 10.3 12.8 11 6.5 1.3 4.5 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF641 PF04859.12 ORY46610.1 - 0.84 10.0 18.6 1.7 9.0 0.7 3.5 2 1 2 4 4 4 0 Plant protein of unknown function (DUF641) DUF1664 PF07889.12 ORY46610.1 - 0.87 9.6 11.7 10 6.2 0.3 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 ORY46610.1 - 1.2 9.1 20.0 6 6.9 2.4 3.6 1 1 3 4 4 4 0 Laminin Domain II DUF2203 PF09969.9 ORY46610.1 - 1.5 9.6 12.1 6.8 7.4 2.3 3.2 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Fib_alpha PF08702.10 ORY46610.1 - 1.6 8.9 15.5 3 8.0 2.6 3.3 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family APG6_N PF17675.1 ORY46610.1 - 1.7 9.1 24.3 0.15 12.6 0.6 3.1 1 1 2 3 3 3 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 ORY46610.1 - 2.1 8.6 24.9 7 6.9 5.5 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4200 PF13863.6 ORY46610.1 - 2.1 8.8 14.9 11 6.4 6.3 3.7 2 2 0 3 3 3 0 Domain of unknown function (DUF4200) LNP1 PF15419.6 ORY46610.1 - 2.2 8.5 5.3 2.1 8.5 0.1 2.2 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 DUF4988 PF16378.5 ORY46610.1 - 2.2 7.9 6.6 2.5 7.7 0.2 3.2 2 1 1 3 3 3 0 Domain of unknown function DUF16 PF01519.16 ORY46610.1 - 2.4 8.7 12.1 21 5.6 3.7 3.3 1 1 2 3 3 3 0 Protein of unknown function DUF16 FapA PF03961.13 ORY46610.1 - 4.1 5.9 16.1 2 6.9 5.9 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A CENP-F_leu_zip PF10473.9 ORY46610.1 - 4.2 7.4 27.1 7.5 6.6 5.1 3.7 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2730 PF10805.8 ORY46610.1 - 4.5 7.4 13.6 11 6.2 0.4 4.2 2 2 1 4 4 4 0 Protein of unknown function (DUF2730) V_ATPase_I PF01496.19 ORY46610.1 - 5.2 4.8 10.2 6.2 4.6 10.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fmp27_WPPW PF10359.9 ORY46610.1 - 6.9 5.4 10.9 1.1 8.0 5.8 1.9 1 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain OmpH PF03938.14 ORY46610.1 - 7.1 7.0 13.3 2 8.7 7.6 2.6 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) CC2-LZ PF16516.5 ORY46610.1 - 7.4 7.0 15.8 4.2 7.8 0.2 3.6 2 2 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator FAP206 PF12018.8 ORY46610.1 - 8.4 5.8 15.3 1.4 8.3 0.6 3.0 1 1 1 3 3 3 0 Domain of unknown function Macoilin PF09726.9 ORY46610.1 - 9.3 4.7 20.2 1.4e+02 0.8 20.2 2.8 1 1 0 1 1 1 0 Macoilin family RhoGAP PF00620.27 ORY46611.1 - 0.014 15.3 0.8 0.046 13.6 0.8 2.0 1 0 0 1 1 1 0 RhoGAP domain 7TMR-HDED PF07697.11 ORY46612.1 - 0.099 12.7 0.2 0.099 12.7 0.2 2.3 2 1 0 2 2 2 0 7TM-HD extracellular F-box-like PF12937.7 ORY46613.1 - 0.034 14.1 0.2 0.068 13.1 0.2 1.5 1 0 0 1 1 1 0 F-box-like Cytochrom_c3_2 PF14537.6 ORY46613.1 - 0.61 10.6 7.5 8.1 7.0 0.8 2.4 2 0 0 2 2 2 0 Cytochrome c3 Ras PF00071.22 ORY46614.1 - 1.4e-45 154.8 0.1 2.7e-44 150.6 0.1 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 ORY46614.1 - 4.9e-16 59.0 0.0 3.6e-15 56.2 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 ORY46614.1 - 1.2e-05 25.2 0.0 0.025 14.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 ORY46614.1 - 0.0028 17.1 0.0 0.05 13.1 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY46614.1 - 0.005 16.4 0.0 0.02 14.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Septin PF00735.18 ORY46614.1 - 0.12 11.6 0.0 1.9 7.7 0.0 2.0 2 0 0 2 2 2 0 Septin MMR_HSR1 PF01926.23 ORY46614.1 - 0.15 12.2 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase PhyH PF05721.13 ORY46615.1 - 4.6e-57 193.7 0.0 5.3e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 ORY46615.1 - 0.028 14.8 0.0 0.054 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase VEGFR-2_TMD PF17988.1 ORY46616.1 - 3.3 7.2 9.6 7.9 6.0 9.6 1.6 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain DUF1295 PF06966.12 ORY46618.1 - 5.4e-18 65.4 1.4 1.7e-17 63.7 1.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) cNMP_binding PF00027.29 ORY46620.1 - 2.3e-09 37.2 0.0 5.1e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain GvpK PF05121.12 ORY46621.1 - 0.096 12.7 1.0 0.2 11.7 1.0 1.5 1 0 0 1 1 1 0 Gas vesicle protein K Ion_trans_2 PF07885.16 ORY46622.1 - 0.037 14.0 0.2 0.056 13.4 0.2 1.3 1 0 0 1 1 1 0 Ion channel CCDC14 PF15254.6 ORY46624.1 - 0.0025 16.6 4.1 0.0046 15.7 4.1 1.3 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 14 MBOAT PF03062.19 ORY46625.1 - 7e-12 45.4 6.9 1e-09 38.2 6.9 2.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Peptidase_M20 PF01546.28 ORY46626.1 - 1.2e-11 44.7 0.0 3.5e-11 43.2 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY46626.1 - 1.8e-05 24.6 0.0 3.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Beta-lactamase PF00144.24 ORY46627.1 - 3e-34 118.7 0.0 5.5e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase 7tm_3 PF00003.22 ORY46627.1 - 2.2e-22 79.9 19.4 3.6e-22 79.3 19.4 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF3471 PF11954.8 ORY46627.1 - 2e-06 28.2 0.1 4.4e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Arb2 PF09757.9 ORY46627.1 - 0.11 11.6 0.2 0.19 10.8 0.2 1.3 1 0 0 1 1 1 0 Arb2 domain WD40 PF00400.32 ORY46628.1 - 2e-13 50.5 5.2 8.8e-06 26.4 1.1 2.2 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY46628.1 - 0.00089 19.5 0.1 1 9.7 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain FlgD_ig PF13860.6 ORY46628.1 - 0.032 14.1 0.2 0.95 9.4 0.0 2.3 2 0 0 2 2 2 0 FlgD Ig-like domain Ge1_WD40 PF16529.5 ORY46628.1 - 0.072 12.0 0.1 1.8 7.4 0.0 2.0 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_M20 PF01546.28 ORY46629.1 - 1.2e-20 74.1 0.0 1.8e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY46629.1 - 2.9e-05 23.9 0.0 6.5e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain OTU PF02338.19 ORY46630.1 - 3e-07 31.0 0.8 5.4e-07 30.1 0.1 1.7 2 0 0 2 2 2 1 OTU-like cysteine protease DUF512 PF04459.12 ORY46630.1 - 0.025 13.8 0.3 0.048 12.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF512) P_C10 PF14974.6 ORY46630.1 - 0.38 10.9 6.0 0.62 10.2 4.4 2.2 1 1 1 2 2 2 0 Protein C10 Peptidase_C65 PF10275.9 ORY46630.1 - 2.6 7.4 7.6 0.46 9.9 0.5 2.4 1 1 2 3 3 3 0 Peptidase C65 Otubain DNA_pol_A_exo1 PF01612.20 ORY46631.1 - 4.7e-12 46.0 0.0 6.8e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease Pkinase_Tyr PF07714.17 ORY46632.1 - 3.3e-28 98.7 0.0 3.7e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORY46632.1 - 1.2e-24 87.2 0.0 1.4e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 ORY46632.1 - 0.00063 19.7 0.0 0.00097 19.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY46632.1 - 0.0028 17.0 0.0 0.0038 16.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY46632.1 - 0.035 13.1 0.0 0.035 13.1 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain YukC PF10140.9 ORY46632.1 - 0.14 10.9 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.14 ORY46632.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 ORY46633.1 - 3.4e-33 115.0 0.0 2.2e-32 112.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORY46633.1 - 2.3e-28 99.3 0.0 2.4e-27 96.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 ORY46633.1 - 0.0031 17.5 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY46633.1 - 0.0035 16.7 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY46633.1 - 0.13 11.2 0.0 0.31 9.9 0.0 1.6 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 ORY46634.1 - 1.5e-36 126.1 0.0 2.2e-35 122.3 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY46634.1 - 4.2e-34 118.0 0.0 3e-32 111.9 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 ORY46634.1 - 0.0046 16.9 0.0 0.0068 16.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 ORY46634.1 - 0.0079 15.5 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY46634.1 - 0.0098 14.9 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY46634.1 - 0.051 12.9 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sel1 PF08238.12 ORY46635.1 - 3.7e-54 179.9 22.9 5.4e-09 36.4 0.2 6.7 7 0 0 7 7 7 6 Sel1 repeat TPR_6 PF13174.6 ORY46635.1 - 8.3e-05 23.0 2.4 7.6 7.4 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat IL22 PF14565.6 ORY46635.1 - 0.025 14.9 0.1 8.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Interleukin 22 IL-10-related T-cell-derived-inducible factor DUF2225 PF09986.9 ORY46635.1 - 0.035 13.8 1.4 0.097 12.4 0.9 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) HP0268 PF18618.1 ORY46635.1 - 0.047 14.1 0.2 1.1 9.7 0.1 2.6 2 1 1 3 3 3 0 HP0268 Ank_2 PF12796.7 ORY46636.1 - 4.1e-21 75.4 0.4 2.8e-07 31.0 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY46636.1 - 1.6e-12 46.4 0.1 0.016 15.7 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 ORY46636.1 - 2.4e-12 47.1 0.7 0.0016 19.0 0.0 4.4 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY46636.1 - 2.6e-11 43.6 2.5 0.0026 18.0 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY46636.1 - 2.8e-08 33.8 5.1 0.01 16.2 0.0 6.1 6 1 1 7 7 7 2 Ankyrin repeat DNA_pol_phi PF04931.13 ORY46636.1 - 0.042 11.9 17.4 0.057 11.5 17.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 ORY46636.1 - 0.36 9.0 13.2 0.48 8.6 13.2 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 ORY46636.1 - 2.5 8.0 10.6 3.7 7.4 10.6 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region GCIP PF13324.6 ORY46636.1 - 2.7 7.5 5.7 4 7.0 5.7 1.2 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting BUD22 PF09073.10 ORY46636.1 - 7 5.9 12.4 9.7 5.4 12.4 1.1 1 0 0 1 1 1 0 BUD22 LRR_8 PF13855.6 ORY46736.1 - 3.6e-13 49.1 12.7 1.9e-07 30.8 0.5 4.1 4 1 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 ORY46736.1 - 7.9e-10 38.8 14.1 0.033 14.6 1.9 5.7 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY46736.1 - 0.00057 20.1 16.5 3.2 8.7 0.1 7.6 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.6 ORY46737.1 - 3.2e-19 68.4 47.7 5.9e-07 29.1 8.0 6.1 2 2 5 7 7 7 5 Leucine rich repeat LRR_4 PF12799.7 ORY46737.1 - 1.5e-12 47.5 29.9 0.00016 22.0 7.2 7.3 3 1 4 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY46737.1 - 3.8e-07 29.7 19.5 1.7 9.5 0.8 8.8 8 2 1 9 9 9 3 Leucine Rich Repeat Dict-STAT-coil PF09267.10 ORY46737.1 - 0.016 15.6 0.3 9.2 6.7 0.0 3.2 1 1 2 3 3 3 0 Dictyostelium STAT, coiled coil DUF3338 PF11819.8 ORY46737.1 - 0.018 15.0 0.0 8.6 6.4 0.0 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF3338) LRR_9 PF14580.6 ORY46737.1 - 0.34 10.4 5.6 8.2 5.9 2.2 3.4 2 1 2 4 4 4 0 Leucine-rich repeat LRR_6 PF13516.6 ORY46737.1 - 1.5 9.1 26.3 9.8 6.5 1.3 7.0 8 0 0 8 8 8 0 Leucine Rich repeat Glyco_hydro_47 PF01532.20 ORY46738.1 - 5.9e-108 361.7 0.0 1e-107 360.9 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 NolX PF05819.11 ORY46738.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 NolX protein Prefoldin PF02996.17 ORY46740.1 - 1.7e-26 92.5 0.8 2.3e-26 92.1 0.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit TMF_TATA_bd PF12325.8 ORY46740.1 - 0.016 15.4 3.3 0.024 14.9 0.1 2.3 2 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 ORY46740.1 - 0.025 14.7 4.4 0.2 11.7 0.5 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.12 ORY46740.1 - 0.028 14.5 1.8 1.4 9.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Mst1_SARAH PF11629.8 ORY46740.1 - 0.047 13.8 0.2 0.12 12.4 0.2 1.7 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 GAS PF13851.6 ORY46740.1 - 0.063 12.6 7.5 1 8.7 1.4 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.20 ORY46740.1 - 0.081 12.9 7.4 1.4 8.9 0.7 2.2 2 0 0 2 2 2 0 Prefoldin subunit ZapB PF06005.12 ORY46740.1 - 0.084 13.3 1.8 0.084 13.3 1.8 2.1 2 0 0 2 2 2 0 Cell division protein ZapB Fib_alpha PF08702.10 ORY46740.1 - 0.16 12.2 4.7 5.6 7.1 0.7 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family RasGAP_C PF03836.15 ORY46740.1 - 0.19 11.9 5.0 0.35 11.0 0.9 2.1 2 0 0 2 2 2 0 RasGAP C-terminus THOC7 PF05615.13 ORY46740.1 - 0.23 11.7 4.0 1.6 9.0 0.5 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 GIT_CC PF16559.5 ORY46740.1 - 0.51 10.3 8.3 0.12 12.2 4.5 2.0 2 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DivIC PF04977.15 ORY46740.1 - 5.7 6.8 8.3 0.97 9.3 3.8 1.9 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.12 ORY46740.1 - 8.2 7.1 9.3 17 6.1 0.9 2.5 2 0 0 2 2 2 0 SlyX ERCC3_RAD25_C PF16203.5 ORY46741.1 - 3.4e-20 72.3 0.1 4.1e-20 72.1 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF4602 PF15375.6 ORY46742.1 - 0.0031 17.8 43.4 0.37 11.1 41.5 3.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4602) Methyltransf_11 PF08241.12 ORY46744.1 - 1.8e-11 44.5 0.0 2.9e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY46744.1 - 5.5e-08 33.4 0.0 9.7e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY46744.1 - 7.3e-05 23.4 0.0 0.00015 22.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY46744.1 - 0.00012 22.0 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY46744.1 - 0.0011 18.8 0.0 0.0013 18.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY46744.1 - 0.0088 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 ORY46744.1 - 0.062 11.9 0.0 0.078 11.5 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase NodS PF05401.11 ORY46744.1 - 0.16 11.5 0.0 0.53 9.9 0.0 1.8 1 1 1 2 2 2 0 Nodulation protein S (NodS) DBI_PRT PF02277.17 ORY46745.1 - 1e-97 327.4 12.0 1.2e-97 327.1 12.0 1.0 1 0 0 1 1 1 1 Phosphoribosyltransferase EF-hand_7 PF13499.6 ORY46746.1 - 8.5e-19 67.8 13.4 6.5e-12 45.7 2.5 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 ORY46746.1 - 4.5e-14 50.8 10.7 3.8e-05 22.9 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 ORY46746.1 - 9.4e-14 50.1 9.7 3e-06 26.7 0.0 5.0 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 ORY46746.1 - 1.9e-07 30.8 12.7 0.0041 16.9 0.3 4.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 ORY46746.1 - 1.4e-05 25.3 0.3 0.069 13.5 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 ORY46746.1 - 4.8e-05 22.7 5.4 0.0095 15.4 0.1 3.8 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 ORY46746.1 - 0.017 15.1 6.9 2.2 8.3 0.1 3.3 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORY46746.1 - 0.061 13.6 0.5 2.3 8.5 0.0 2.5 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Methyltransf_32 PF13679.6 ORY46747.1 - 2.6e-26 92.5 0.2 4.6e-26 91.7 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY46747.1 - 0.0005 19.7 0.0 0.00091 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain TRM13 PF05206.14 ORY46747.1 - 0.0056 16.2 0.3 0.012 15.1 0.2 1.5 1 1 0 1 1 1 1 Methyltransferase TRM13 Methyltransf_2 PF00891.18 ORY46747.1 - 0.0072 15.6 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_31 PF13847.6 ORY46747.1 - 0.044 13.6 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain RNA_pol_I_TF PF04090.12 ORY46747.1 - 0.06 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific initiation factor Methyltransf_25 PF13649.6 ORY46747.1 - 0.072 13.8 0.0 0.3 11.8 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain RrnaAD PF00398.20 ORY46747.1 - 0.12 11.4 0.0 0.36 9.9 0.0 1.7 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Mito_carr PF00153.27 ORY46750.1 - 6.7e-63 208.7 6.0 4.6e-21 74.5 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3764 PF12594.8 ORY46750.1 - 0.0067 16.5 0.0 14 5.8 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3764) Methyltransf_16 PF10294.9 ORY46753.1 - 7.7e-07 29.0 5.2 0.00014 21.7 1.2 2.2 1 1 1 2 2 2 2 Lysine methyltransferase MTS PF05175.14 ORY46753.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Cys_Met_Meta_PP PF01053.20 ORY46754.1 - 0.019 13.5 0.4 0.17 10.4 0.2 2.4 1 1 1 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme DUF4148 PF13663.6 ORY46754.1 - 0.28 11.4 2.3 0.5 10.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Glyco_transf_28 PF03033.20 ORY46755.1 - 1.7e-11 44.3 0.0 3.6e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 ORY46755.1 - 1.6e-06 28.2 0.0 2.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 ORY46755.1 - 0.0017 17.2 0.0 0.0032 16.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase GST_C_3 PF14497.6 ORY46756.1 - 3.4e-27 94.5 0.1 5.6e-27 93.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY46756.1 - 4.9e-05 23.3 0.0 0.00011 22.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY46756.1 - 0.0024 18.1 0.1 0.0077 16.4 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Bax1-I PF01027.20 ORY46757.1 - 5.5e-36 124.3 25.1 1.5e-32 113.1 18.5 2.0 1 1 1 2 2 2 2 Inhibitor of apoptosis-promoting Bax1 Mntp PF02659.15 ORY46757.1 - 0.032 14.0 2.6 0.06 13.1 2.6 1.4 1 0 0 1 1 1 0 Putative manganese efflux pump CCB1 PF12046.8 ORY46757.1 - 1.4 8.2 6.6 3.1 7.1 6.6 1.8 1 1 0 1 1 1 0 Cofactor assembly of complex C subunit B DUF2070 PF09843.9 ORY46757.1 - 6 5.0 17.7 6.4 4.9 17.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RF-1 PF00472.20 ORY46758.1 - 3.1e-22 78.7 5.7 4.6e-22 78.1 5.7 1.3 1 0 0 1 1 1 1 RF-1 domain DUF4407 PF14362.6 ORY46758.1 - 6.2 6.1 7.0 7.1 5.9 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) NTP_transf_2 PF01909.23 ORY46759.1 - 2.6e-11 43.6 1.7 7.6e-11 42.2 0.0 2.5 2 1 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 ORY46759.1 - 0.01 15.9 0.0 0.029 14.4 0.0 1.7 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Orthopox_F8 PF05886.11 ORY46759.1 - 0.13 12.4 0.6 0.43 10.7 0.6 1.9 1 0 0 1 1 1 0 Orthopoxvirus F8 protein DUF4464 PF14713.6 ORY46761.1 - 1.2e-45 155.8 2.6 6.5e-45 153.4 2.6 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4464) Kelch_5 PF13854.6 ORY46762.1 - 0.017 15.1 0.4 0.019 15.0 0.4 1.2 1 0 0 1 1 1 0 Kelch motif cNMP_binding PF00027.29 ORY46764.1 - 4.4e-17 61.9 0.0 9.9e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain OstA PF03968.14 ORY46764.1 - 0.064 13.5 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 OstA-like protein Cupin_3 PF05899.12 ORY46764.1 - 0.065 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Ion_trans_2 PF07885.16 ORY46764.1 - 2 8.4 7.0 0.14 12.1 0.3 2.6 2 0 0 2 2 2 0 Ion channel DUF441 PF04284.13 ORY46765.1 - 0.61 10.1 8.2 0.18 11.8 1.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF441) ABC_membrane PF00664.23 ORY46766.1 - 1.9e-43 149.1 2.4 2.6e-43 148.6 2.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ORY46766.1 - 6.8e-17 62.3 0.0 1.6e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 ORY46766.1 - 4.9e-05 23.8 1.8 0.00017 22.0 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.12 ORY46766.1 - 0.0011 18.3 0.0 0.0035 16.7 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.26 ORY46766.1 - 0.0071 16.1 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_15 PF13175.6 ORY46766.1 - 0.0095 15.7 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ORY46766.1 - 0.013 15.2 0.1 0.034 13.9 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.17 ORY46766.1 - 0.022 14.9 1.0 0.039 14.0 0.1 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 ORY46766.1 - 0.041 14.1 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ORY46766.1 - 0.085 13.0 0.0 0.27 11.3 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 ORY46766.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region LysM PF01476.20 ORY46768.1 - 2.7e-12 46.5 0.2 1.3e-07 31.5 0.2 2.3 2 0 0 2 2 2 2 LysM domain HTH_23 PF13384.6 ORY46768.1 - 0.12 12.2 0.0 20 5.2 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain ABC_membrane PF00664.23 ORY46769.1 - 5.8e-32 111.4 6.3 7.5e-19 68.4 0.4 3.2 1 1 2 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 ORY46769.1 - 3.1e-16 60.1 0.0 2.5e-15 57.2 0.0 2.5 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 ORY46769.1 - 1.6e-06 28.6 0.1 5.1e-06 27.0 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 ORY46769.1 - 5.2e-05 22.8 0.5 0.07 12.6 0.1 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORY46769.1 - 0.0026 18.0 0.0 0.014 15.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.6 ORY46769.1 - 0.0052 16.5 0.0 0.0085 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ORY46769.1 - 0.0095 15.7 0.2 0.025 14.3 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain 7tm_1 PF00001.21 ORY46769.1 - 0.025 13.9 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF87 PF01935.17 ORY46769.1 - 0.03 14.4 0.1 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 ORY46769.1 - 0.037 13.7 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.12 ORY46769.1 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.26 ORY46769.1 - 0.073 12.8 0.0 0.66 9.7 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 ORY46769.1 - 0.076 12.7 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY46769.1 - 0.094 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 ORY46769.1 - 0.099 13.1 0.0 0.68 10.4 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY46769.1 - 0.12 12.4 0.0 0.42 10.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DEAD PF00270.29 ORY46769.1 - 0.13 12.0 0.0 21 4.8 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF953 PF06110.11 ORY46771.1 - 7e-26 90.2 0.0 8.8e-26 89.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 ORY46771.1 - 0.00026 20.9 0.1 0.0012 18.8 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 ORY46771.1 - 0.0074 16.1 0.1 0.011 15.5 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 ORY46771.1 - 0.11 12.8 0.0 16 5.9 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like DUF3566 PF12089.8 ORY46772.1 - 0.39 11.1 5.7 0.31 11.4 2.1 2.4 2 1 0 2 2 2 0 Transmembrane domain of unknown function (DUF3566) ArAE_2_N PF10337.9 ORY46773.1 - 0.14 11.2 3.1 0.22 10.5 3.1 1.3 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Wzy_C PF04932.15 ORY46773.1 - 4 7.0 9.4 10 5.7 9.4 1.8 1 1 0 1 1 1 0 O-Antigen ligase SLATT_1 PF18181.1 ORY46774.1 - 0.024 14.6 1.6 0.024 14.6 0.2 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Sdh_cyt PF01127.22 ORY46776.1 - 6.9e-25 87.4 5.3 9.7e-25 86.9 5.3 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit SRP40_C PF05022.12 ORY46777.1 - 6e-29 100.7 6.1 3.7e-28 98.2 6.1 2.4 1 0 0 1 1 1 1 SRP40, C-terminal domain HC2 PF07382.11 ORY46777.1 - 0.12 12.4 31.1 52 3.8 31.2 3.2 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Myb_Cef PF11831.8 ORY46778.1 - 1.9e-27 96.4 1.1 1.9e-27 96.4 1.1 3.8 4 0 0 4 4 4 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 ORY46778.1 - 8.3e-22 77.1 3.6 7.9e-12 45.2 1.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY46778.1 - 1.3e-19 70.1 5.3 4.5e-13 49.2 3.0 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 ORY46778.1 - 0.27 11.3 2.0 0.98 9.6 0.1 2.6 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Glyco_transf_28 PF03033.20 ORY46779.1 - 7.4e-13 48.7 0.0 1.1e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_transf_28 PF03033.20 ORY46780.1 - 3.5e-07 30.4 0.0 9.1e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 ORY46780.1 - 5.1e-07 29.8 0.0 8.5e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 ORY46780.1 - 0.0069 15.2 0.1 0.012 14.4 0.1 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase RRM_1 PF00076.22 ORY46781.1 - 2.9e-38 129.5 0.0 1.8e-19 69.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY46781.1 - 2.8e-05 24.1 0.1 0.0008 19.5 0.0 2.5 2 1 0 2 2 2 1 RNA recognition motif Limkain-b1 PF11608.8 ORY46781.1 - 0.002 18.2 0.1 0.37 10.9 0.1 2.3 2 0 0 2 2 2 2 Limkain b1 OB_RNB PF08206.11 ORY46781.1 - 0.0026 17.4 1.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain RRM_5 PF13893.6 ORY46781.1 - 0.028 14.0 0.0 4.8 6.8 0.0 2.3 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CBS PF00571.28 ORY46783.1 - 1.4e-26 92.7 0.6 4.2e-07 30.3 0.0 5.1 5 0 0 5 5 5 4 CBS domain DUF975 PF06161.11 ORY46785.1 - 3.6 7.3 14.0 2.9 7.6 12.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF975) Methyltransf_32 PF13679.6 ORY46786.1 - 7.1e-23 81.3 0.0 1.2e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY46786.1 - 0.0054 16.3 0.0 0.0094 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 ORY46786.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain TRM13 PF05206.14 ORY46786.1 - 0.026 14.1 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase TRM13 ABC_membrane_2 PF06472.15 ORY46787.1 - 3.2e-94 315.3 4.5 4.3e-94 314.9 4.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 ORY46787.1 - 5.5e-19 69.0 0.0 1.1e-18 68.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ORY46787.1 - 0.00037 20.0 0.0 0.3 10.5 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ORY46787.1 - 0.00042 20.2 0.0 0.0011 18.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Mg_chelatase PF01078.21 ORY46787.1 - 0.0029 17.0 0.0 0.0062 15.9 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI SbmA_BacA PF05992.12 ORY46787.1 - 0.0032 17.0 0.3 0.005 16.3 0.3 1.2 1 0 0 1 1 1 1 SbmA/BacA-like family AAA_18 PF13238.6 ORY46787.1 - 0.0041 17.7 0.0 0.0086 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY46787.1 - 0.017 15.5 0.0 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 ORY46787.1 - 0.02 14.6 0.0 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ORY46787.1 - 0.032 14.8 0.1 0.092 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ORY46787.1 - 0.046 14.0 0.0 0.18 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 ORY46787.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 ORY46787.1 - 0.12 12.7 0.0 1.3 9.5 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 ORY46787.1 - 0.14 11.9 0.2 1.3 8.7 0.0 2.5 3 0 0 3 3 3 0 Cytidylate kinase MFS_1 PF07690.16 ORY46788.1 - 6.6e-23 81.2 25.3 6.6e-23 81.2 25.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 ORY46788.1 - 0.022 13.2 1.2 0.045 12.1 1.2 1.5 1 0 0 1 1 1 0 Transmembrane secretion effector DUF2470 PF10615.9 ORY46789.1 - 9.9e-08 32.5 0.0 1.6e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.6 ORY46789.1 - 2e-06 28.1 0.8 5.6e-06 26.6 0.7 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4499) Osw5 PF17062.5 ORY46791.1 - 5.2 7.2 11.9 0.048 13.7 2.2 2.7 3 0 0 3 3 3 0 Outer spore wall 5 ABC_tran PF00005.27 ORY46792.1 - 1.4e-27 96.9 0.0 2.4e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ORY46792.1 - 5.9e-07 29.4 0.9 8.1e-07 29.0 0.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ORY46792.1 - 0.00069 19.1 0.4 0.02 14.3 0.4 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY46792.1 - 0.021 14.9 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase TPT PF03151.16 ORY46793.1 - 7.9e-25 87.8 22.8 1e-24 87.4 22.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 ORY46793.1 - 8.6e-09 35.0 25.4 1.9e-08 33.9 25.4 1.5 1 1 0 1 1 1 1 UAA transporter family Epimerase PF01370.21 ORY46795.1 - 4.4e-24 85.3 0.0 2.8e-23 82.6 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY46795.1 - 9.6e-22 77.3 0.2 2.4e-21 76.0 0.1 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORY46795.1 - 6.9e-20 71.3 0.1 1.4e-17 63.8 0.1 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 ORY46795.1 - 1.2e-16 61.2 0.2 1.7e-16 60.7 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ORY46795.1 - 2.3e-16 60.1 0.0 1.9e-14 53.8 0.0 2.5 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ORY46795.1 - 3.9e-10 39.3 0.5 2.8e-09 36.5 0.5 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 ORY46795.1 - 7.1e-10 38.8 0.1 1.5e-09 37.8 0.2 1.5 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 ORY46795.1 - 3.7e-08 32.8 0.1 5e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 ORY46795.1 - 0.00012 22.1 0.3 0.00074 19.5 0.3 2.0 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 ORY46795.1 - 0.0019 17.7 0.1 0.0032 16.9 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.17 ORY46795.1 - 0.013 16.1 0.1 0.031 14.8 0.1 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 ORY46795.1 - 0.034 14.4 0.1 0.066 13.5 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 ORY46795.1 - 0.04 14.2 0.2 0.42 10.9 0.0 2.5 3 0 0 3 3 3 0 TrkA-N domain Methyltransf_31 PF13847.6 ORY46795.1 - 0.048 13.4 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Semialdhyde_dh PF01118.24 ORY46795.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ThrE PF06738.12 ORY46798.1 - 8.6e-25 87.5 8.1 6.1e-23 81.4 0.1 2.6 2 0 0 2 2 2 2 Putative threonine/serine exporter DUF4874 PF16173.5 ORY46798.1 - 0.053 13.2 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4874) Pox_P35 PF03213.14 ORY46798.1 - 0.081 12.1 0.2 0.13 11.4 0.2 1.2 1 0 0 1 1 1 0 Poxvirus P35 protein ThrE_2 PF12821.7 ORY46798.1 - 0.18 12.0 6.8 0.053 13.7 3.2 2.0 2 1 0 2 2 2 0 Threonine/Serine exporter, ThrE zf-C3HC4 PF00097.25 ORY46800.1 - 0.0076 16.1 14.0 1.2 9.1 11.0 2.7 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY46800.1 - 0.14 12.5 20.8 0.56 10.6 18.2 3.0 2 1 0 2 2 2 0 Ring finger domain Pheromone PF08015.11 ORY46800.1 - 0.54 11.3 5.5 0.18 12.8 2.0 2.1 2 0 0 2 2 2 0 Fungal mating-type pheromone zf-C3HC4_2 PF13923.6 ORY46800.1 - 1 9.3 18.0 3.1 7.7 10.4 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY46800.1 - 6.9 6.6 16.4 64 3.5 16.4 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) HSP20 PF00011.21 ORY46801.1 - 1.8e-19 69.7 0.1 2.2e-19 69.5 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORY46801.1 - 3.8e-10 39.2 0.0 5.3e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA adh_short PF00106.25 ORY46802.1 - 6.4e-15 55.1 0.7 3.9e-13 49.3 0.2 2.6 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY46802.1 - 1.1e-07 31.7 0.2 1.5e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Ribosomal_L2_C PF03947.18 ORY46804.1 - 2.3e-45 153.8 5.9 3.5e-45 153.3 5.9 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 ORY46804.1 - 2.5e-13 49.8 0.1 6.7e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain APH PF01636.23 ORY46805.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 ORY46805.1 - 0.021 14.2 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family cNMP_binding PF00027.29 ORY46806.1 - 5.4e-08 32.8 0.1 1.9e-07 31.1 0.1 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Cupin_3 PF05899.12 ORY46806.1 - 0.017 14.8 0.1 0.031 13.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_2 PF07883.11 ORY46806.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Cupin domain Lactamase_B_2 PF12706.7 ORY46807.1 - 8.8e-33 113.5 0.0 1.5e-32 112.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORY46807.1 - 2.3e-11 43.9 0.0 8.4e-11 42.0 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY46807.1 - 0.0062 16.6 0.0 0.027 14.5 0.0 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Glyco_hydro_18 PF00704.28 ORY46808.1 - 3.4e-59 201.1 3.0 4.2e-59 200.8 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Aminotran_1_2 PF00155.21 ORY46810.1 - 1.3e-63 215.4 0.0 1.7e-63 215.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 ORY46810.1 - 0.001 17.9 0.0 0.002 16.9 0.0 1.5 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 ORY46810.1 - 0.0014 18.0 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 ORY46810.1 - 0.014 14.3 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V DUF5448 PF17526.2 ORY46810.1 - 0.027 14.6 0.0 0.053 13.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5448) Cys_Met_Meta_PP PF01053.20 ORY46810.1 - 0.15 10.5 0.0 0.27 9.7 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Lipase_3 PF01764.25 ORY46811.1 - 5e-09 36.2 0.0 1.4e-08 34.7 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) GPI-anchored PF10342.9 ORY46812.1 - 0.00013 22.6 5.6 0.35 11.7 1.3 3.8 3 0 0 3 3 3 2 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family 7tm_1 PF00001.21 ORY46813.1 - 0.00042 19.7 6.3 0.00042 19.7 6.3 2.0 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) SBF_like PF13593.6 ORY46814.1 - 0.073 12.4 7.0 0.14 11.4 0.3 2.3 1 1 1 2 2 2 0 SBF-like CPA transporter family (DUF4137) Arif-1 PF06770.11 ORY46814.1 - 0.082 12.6 9.8 0.098 12.3 0.1 2.3 2 0 0 2 2 2 0 Actin-rearrangement-inducing factor (Arif-1) DUF2157 PF09925.9 ORY46814.1 - 1.4 8.7 10.9 12 5.7 7.7 3.2 1 1 2 3 3 3 0 Predicted membrane protein (DUF2157) Polysacc_synt_C PF14667.6 ORY46814.1 - 6.9 6.7 14.8 0.56 10.3 2.7 3.0 2 1 2 4 4 4 0 Polysaccharide biosynthesis C-terminal domain Rad51 PF08423.11 ORY46815.1 - 3e-12 46.3 0.8 4.5e-12 45.8 0.3 1.5 2 0 0 2 2 2 1 Rad51 HHH_5 PF14520.6 ORY46815.1 - 6.8e-05 23.4 1.8 0.00012 22.6 1.1 1.8 1 1 0 1 1 1 1 Helix-hairpin-helix domain HHH_3 PF12836.7 ORY46815.1 - 0.015 15.5 0.2 0.033 14.4 0.1 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif RNA_pol_A_CTD PF03118.15 ORY46815.1 - 0.053 13.3 0.2 0.053 13.3 0.2 1.7 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain Rad51 PF08423.11 ORY46816.1 - 3.2e-18 65.9 0.0 3.4e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 Rad51 MG2 PF01835.19 ORY46817.1 - 0.029 14.8 0.0 0.062 13.8 0.0 1.6 1 1 0 1 1 1 0 MG2 domain DUF2185 PF09951.9 ORY46817.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2185) zf-MYND PF01753.18 ORY46820.1 - 2.7e-12 46.6 3.9 2.7e-12 46.6 3.9 3.2 3 1 1 4 4 4 1 MYND finger 3Beta_HSD PF01073.19 ORY46823.1 - 7.3e-30 103.9 0.0 1.1e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY46823.1 - 1.5e-20 73.7 0.3 1.2e-19 70.7 0.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ORY46823.1 - 6.9e-09 35.2 2.0 9.6e-08 31.5 0.1 2.3 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 ORY46823.1 - 2.4e-08 34.1 0.0 3.5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ORY46823.1 - 5.3e-05 22.8 0.1 0.0002 20.9 0.2 1.9 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ORY46823.1 - 0.0059 15.8 1.5 0.045 12.9 1.5 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 ORY46823.1 - 0.0065 16.4 1.6 0.11 12.4 1.6 2.3 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 ORY46823.1 - 0.019 14.5 0.0 0.036 13.5 0.0 1.5 1 1 0 1 1 1 0 short chain dehydrogenase Abhydrolase_1 PF00561.20 ORY46824.1 - 4.7e-26 92.0 0.0 5.3e-25 88.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY46824.1 - 2.9e-14 54.2 0.0 2.9e-14 54.2 0.0 2.3 2 1 1 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY46824.1 - 1e-12 47.8 0.0 1.2e-07 31.2 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Thioesterase PF00975.20 ORY46824.1 - 0.013 15.6 0.0 0.031 14.4 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_2 PF02230.16 ORY46824.1 - 0.02 14.7 0.0 0.58 9.9 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.13 ORY46824.1 - 0.023 14.6 0.0 0.062 13.2 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase PGAP1 PF07819.13 ORY46824.1 - 0.025 14.3 0.1 1.6 8.3 0.0 2.5 3 0 0 3 3 3 0 PGAP1-like protein Abhydrolase_4 PF08386.10 ORY46824.1 - 0.044 13.9 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Esterase_phd PF10503.9 ORY46824.1 - 0.085 12.3 0.0 4.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Esterase PHB depolymerase Peptidase_S9 PF00326.21 ORY46824.1 - 0.13 11.7 0.1 0.54 9.7 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family UPF0227 PF05728.12 ORY46824.1 - 0.13 12.1 0.0 2.4 8.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DLH PF01738.18 ORY46824.1 - 0.2 11.2 0.0 15 5.1 0.0 2.4 2 1 0 2 2 2 0 Dienelactone hydrolase family TIR_2 PF13676.6 ORY46825.1 - 2.4e-14 53.9 0.0 7.8e-14 52.3 0.0 1.9 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 ORY46825.1 - 0.026 14.3 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 TIR domain Pkinase PF00069.25 ORY46826.1 - 4.3e-73 245.9 0.0 4.9e-73 245.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY46826.1 - 5.3e-30 104.6 0.0 6.8e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY46826.1 - 0.037 13.3 0.0 0.063 12.6 0.0 1.4 1 1 0 1 1 1 0 Kinase-like TFIID_20kDa PF03847.13 ORY46827.1 - 7.9e-20 71.1 0.0 1.6e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A STN1_2 PF09170.10 ORY46827.1 - 0.0089 16.3 8.7 0.0089 16.3 8.7 3.5 3 1 0 3 3 3 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 CBFD_NFYB_HMF PF00808.23 ORY46827.1 - 0.053 13.8 0.4 0.24 11.7 0.0 2.2 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-18kDa PF02269.16 ORY46827.1 - 0.4 10.7 0.0 0.4 10.7 0.0 3.2 3 0 0 3 3 3 0 Transcription initiation factor IID, 18kD subunit X PF00739.19 ORY46828.1 - 0.11 12.6 0.3 0.16 12.1 0.2 1.3 1 1 0 1 1 1 0 Trans-activation protein X FAD_binding_4 PF01565.23 ORY46829.1 - 4e-13 49.3 0.8 7e-13 48.5 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 ORY46829.1 - 2.9e-10 40.1 0.2 9.4e-10 38.4 0.2 1.9 1 0 0 1 1 1 1 Berberine and berberine like Chitin_bind_1 PF00187.19 ORY46829.1 - 0.063 13.8 12.1 0.097 13.2 12.1 1.3 1 0 0 1 1 1 0 Chitin recognition protein MFS_1 PF07690.16 ORY46831.1 - 8.6e-11 41.3 31.7 8.6e-11 41.3 31.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 ORY46831.1 - 0.019 14.6 15.2 0.084 12.6 1.3 3.8 4 1 0 4 4 4 0 Ion channel regulatory protein UNC-93 DUF1218 PF06749.12 ORY46831.1 - 0.096 13.2 0.1 0.096 13.2 0.1 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF1218) ADH_N PF08240.12 ORY46832.1 - 4.4e-22 78.0 0.1 7.8e-22 77.2 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 ORY46832.1 - 0.00022 21.2 0.0 0.00059 19.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 ORY46832.1 - 0.05 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus FH2 PF02181.23 ORY46833.1 - 4.1e-36 124.9 1.6 8.2e-36 123.9 0.1 2.0 2 0 0 2 2 2 1 Formin Homology 2 Domain PTEN_C2 PF10409.9 ORY46833.1 - 2.3e-08 33.9 0.0 4.1e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DUF4038 PF13204.6 ORY46833.1 - 0.004 16.8 0.0 0.0095 15.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Y_phosphatase3 PF13350.6 ORY46833.1 - 0.0088 16.0 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 ORY46833.1 - 0.022 14.3 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase HEPN_Toprim_N PF18871.1 ORY46833.1 - 0.071 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 DSPc PF00782.20 ORY46833.1 - 0.14 12.0 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain OsmC PF02566.19 ORY46834.1 - 4.7e-10 39.9 0.0 1.3e-09 38.4 0.0 1.7 1 1 0 1 1 1 1 OsmC-like protein NTP_transf_3 PF12804.7 ORY46836.1 - 0.09 13.1 0.6 1.8 8.9 0.0 2.3 2 0 0 2 2 2 0 MobA-like NTP transferase domain SR-25 PF10500.9 ORY46837.1 - 0.97 9.0 9.9 1.2 8.7 9.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CorA PF01544.18 ORY46839.1 - 2.8e-19 69.5 4.2 8.7e-19 67.9 4.2 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Nucleos_tra2_C PF07662.13 ORY46839.1 - 0.018 14.9 0.1 0.02 14.7 0.1 1.1 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter C-terminus DUF3384 PF11864.8 ORY46839.1 - 0.021 13.7 0.2 0.025 13.5 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) BLYB PF05289.11 ORY46839.1 - 0.064 13.5 0.8 0.087 13.0 0.8 1.2 1 0 0 1 1 1 0 Borrelia hemolysin accessory protein HILPDA PF15220.6 ORY46840.1 - 0.069 13.3 0.0 0.44 10.7 0.0 2.2 3 0 0 3 3 3 0 Hypoxia-inducible lipid droplet-associated CoA_transf_3 PF02515.17 ORY46841.1 - 1.4e-63 215.3 0.1 3.2e-62 210.8 0.1 2.6 1 1 0 1 1 1 1 CoA-transferase family III DJ-1_PfpI PF01965.24 ORY46842.1 - 1.9e-15 57.1 0.0 1.5e-14 54.1 0.0 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family Glyco_hydro_76 PF03663.14 ORY46843.1 - 2.7e-41 142.3 15.9 3.9e-41 141.8 15.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Beta_helix PF13229.6 ORY46843.1 - 0.18 11.6 5.2 0.42 10.5 4.6 2.0 1 1 0 1 1 1 0 Right handed beta helix region TPR_1 PF00515.28 ORY46844.1 - 2e-26 90.7 0.5 5.4e-09 35.5 0.1 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY46844.1 - 3.4e-23 79.8 3.0 2.1e-07 30.5 0.2 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 ORY46844.1 - 4.9e-17 62.3 5.0 4.1e-05 24.1 0.0 4.3 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORY46844.1 - 1.8e-14 53.1 0.6 9.2e-08 31.6 0.0 4.9 2 2 3 5 5 5 3 TPR repeat TPR_8 PF13181.6 ORY46844.1 - 2.4e-14 52.2 3.0 5e-07 29.4 0.1 5.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY46844.1 - 4.2e-14 52.8 0.8 1.3e-05 25.6 0.1 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY46844.1 - 5.3e-14 51.7 0.5 0.00018 22.1 0.0 4.4 5 1 1 6 6 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORY46844.1 - 6.7e-13 48.0 4.7 0.038 14.4 0.0 5.3 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 ORY46844.1 - 6.3e-10 38.4 1.5 0.0027 17.6 0.0 4.6 4 1 0 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY46844.1 - 2.8e-08 33.9 3.6 7.8e-05 22.8 0.2 3.2 2 2 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 ORY46844.1 - 4.3e-08 33.3 3.3 0.00032 20.9 0.1 4.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 ORY46844.1 - 3.8e-06 27.2 0.0 0.22 11.9 0.0 3.4 3 2 0 3 3 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY46844.1 - 4.9e-06 26.8 2.8 1.3 9.8 0.0 5.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 ORY46844.1 - 5.8e-06 25.7 0.2 0.097 11.9 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY46844.1 - 1.8e-05 24.8 0.8 0.013 15.7 0.0 3.6 2 2 2 4 4 4 2 Tetratricopeptide repeat MIT PF04212.18 ORY46844.1 - 0.0034 17.4 0.9 0.77 9.9 0.0 3.6 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 ORY46844.1 - 0.015 15.3 0.0 2 8.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 ORY46844.1 - 0.018 14.5 0.5 5.5 6.5 0.0 3.2 3 0 0 3 3 3 0 SHNi-TPR TPR_10 PF13374.6 ORY46844.1 - 0.066 13.1 0.4 0.066 13.1 0.4 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4407 PF14362.6 ORY46845.1 - 4.3 6.6 14.2 8.7 5.6 14.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GHMP_kinases_N PF00288.26 ORY46847.1 - 2.8e-08 33.9 0.0 1.2e-07 31.8 0.0 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain Pkinase PF00069.25 ORY46848.1 - 5.6e-33 114.4 0.0 1.2e-23 83.9 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY46848.1 - 3.2e-11 43.0 0.0 4.9e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY46848.1 - 6.9e-06 25.6 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 ORY46849.1 - 6.5e-16 58.5 0.0 1.8e-09 37.4 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY46849.1 - 9.7e-05 21.8 0.0 0.00056 19.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 ORY46850.1 - 0.019 15.5 0.0 0.39 11.3 0.0 2.5 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_2 PF12796.7 ORY46851.1 - 1.8e-07 31.7 0.1 0.15 12.7 0.0 5.3 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY46851.1 - 0.017 15.7 0.9 0.84 10.3 0.1 3.7 6 0 0 6 6 6 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY46851.1 - 0.12 13.0 4.5 5.6e+02 1.7 0.0 6.8 9 1 1 10 10 10 0 Ankyrin repeat UAA PF08449.11 ORY46852.1 - 1.5e-09 37.5 12.5 1.9e-09 37.2 12.5 1.2 1 0 0 1 1 1 1 UAA transporter family Mannosyl_trans3 PF11051.8 ORY46853.1 - 1.7e-38 132.6 0.1 4.7e-38 131.1 0.1 1.6 1 1 0 1 1 1 1 Mannosyltransferase putative DUF3584 PF12128.8 ORY46854.1 - 2.1 5.7 37.1 2.6 5.5 37.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) GREB1 PF15782.5 ORY46854.1 - 2.9 4.9 22.6 3.7 4.5 22.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LGT PF01790.18 ORY46855.1 - 0.018 14.3 0.0 0.021 14.1 0.0 1.1 1 0 0 1 1 1 0 Prolipoprotein diacylglyceryl transferase DUF5043 PF16446.5 ORY46855.1 - 0.088 12.8 0.0 0.31 11.0 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5043) Zn_clus PF00172.18 ORY46856.1 - 0.00031 20.8 10.5 0.00067 19.7 10.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2046 PF09755.9 ORY46858.1 - 0.00051 19.4 0.5 0.00097 18.5 0.5 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) Cu-oxidase_4 PF02578.15 ORY46859.1 - 4.8 6.7 8.0 1.2 8.6 1.8 2.9 2 2 0 2 2 2 0 Multi-copper polyphenol oxidoreductase laccase Pkinase PF00069.25 ORY46860.1 - 5e-38 131.0 0.0 6.6e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY46860.1 - 2.3e-13 50.1 0.1 2.4e-07 30.3 0.1 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase DUF3421 PF11901.8 ORY46861.1 - 6.8e-11 42.2 0.2 8.9e-11 41.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3421) Mpp10 PF04006.12 ORY46862.1 - 7e-101 338.6 69.6 2.5e-80 270.7 12.3 4.0 2 1 2 4 4 4 3 Mpp10 protein KIAA1430 PF13879.6 ORY46864.1 - 3e-15 56.8 16.2 4.4e-15 56.3 16.2 1.3 1 0 0 1 1 1 1 KIAA1430 homologue Mg_chelatase_C PF13335.6 ORY46864.1 - 0.12 13.1 0.9 1 10.0 0.7 2.2 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal DUF3421 PF11901.8 ORY46865.1 - 6.7e-53 177.6 6.2 5.9e-20 71.4 0.1 4.6 1 1 3 4 4 4 4 Protein of unknown function (DUF3421) MHYT PF03707.16 ORY46866.1 - 1.3e-10 41.2 12.2 1.1e-05 25.5 5.1 3.7 3 1 0 3 3 3 3 Bacterial signalling protein N terminal repeat Ank_2 PF12796.7 ORY46867.1 - 4.7e-17 62.4 0.2 6e-12 46.0 0.3 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORY46867.1 - 8.6e-17 60.8 1.8 5.8e-05 23.3 0.2 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 ORY46867.1 - 3.5e-15 56.1 0.9 1.1e-07 32.3 0.2 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY46867.1 - 3.3e-14 51.6 0.3 0.0025 18.1 0.1 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 ORY46867.1 - 2.2e-13 50.1 6.0 1.4e-06 28.4 1.5 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY46868.1 - 1.2e-20 73.3 0.5 3e-09 37.0 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY46868.1 - 3.7e-19 68.8 0.3 1.2e-09 38.5 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY46868.1 - 8.7e-19 67.1 0.7 4.9e-07 29.9 0.0 3.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.7 ORY46868.1 - 1.3e-18 67.3 0.1 4.1e-18 65.7 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY46868.1 - 4.6e-16 57.3 0.6 0.0012 19.1 0.0 3.4 4 0 0 4 4 4 3 Ankyrin repeat DUF4126 PF13548.6 ORY46868.1 - 0.011 15.5 0.1 0.013 15.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4126) MT-A70 PF05063.14 ORY46869.1 - 5.4e-39 133.9 0.0 6e-39 133.7 0.0 1.0 1 0 0 1 1 1 1 MT-A70 STb_secrete PF09075.10 ORY46869.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Heat-stable enterotoxin B, secretory Pex24p PF06398.11 ORY46870.1 - 8.8e-29 100.6 19.3 4.2e-19 68.8 7.9 2.1 1 1 1 2 2 2 2 Integral peroxisomal membrane peroxin C1_1 PF00130.22 ORY46870.1 - 1.1e-13 50.8 5.3 1.1e-13 50.8 5.3 1.9 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Reticulon PF02453.17 ORY46870.1 - 0.0016 18.4 0.1 0.0016 18.4 0.1 1.8 2 0 0 2 2 2 1 Reticulon Sugar_tr PF00083.24 ORY46871.1 - 3.5e-47 161.3 27.0 4.1e-47 161.1 27.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY46871.1 - 5.5e-21 74.9 24.7 5.5e-21 74.9 24.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Pkinase PF00069.25 ORY46873.1 - 4e-52 177.2 0.0 5.5e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY46873.1 - 3.4e-21 75.7 0.0 5.2e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4476 PF14771.6 ORY46873.1 - 0.037 14.3 0.2 0.09 13.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4476) RIO1 PF01163.22 ORY46873.1 - 0.11 12.1 1.0 0.88 9.1 1.0 2.0 1 1 0 1 1 1 0 RIO1 family Lectin_leg-like PF03388.13 ORY46874.1 - 6.9e-65 218.6 0.3 9e-65 218.2 0.3 1.1 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 ORY46874.1 - 1.2e-08 35.2 0.9 1.7e-08 34.7 0.9 1.1 1 0 0 1 1 1 1 Bacterial lectin TUDOR PF00567.24 ORY46874.1 - 0.059 13.4 0.0 0.44 10.6 0.0 2.0 2 0 0 2 2 2 0 Tudor domain Sugar_tr PF00083.24 ORY46875.1 - 8.6e-18 64.4 21.3 1.3e-11 44.0 12.5 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter Ribosomal_L7Ae PF01248.26 ORY46876.1 - 1.5e-26 91.9 0.1 1.9e-26 91.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 ORY46876.1 - 0.0005 19.9 0.0 0.00065 19.5 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 ORY46876.1 - 0.0055 16.8 0.1 0.006 16.6 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 S4 PF01479.25 ORY46877.1 - 1.4e-11 43.9 0.2 5e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 ORY46877.1 - 1.5e-10 41.8 1.1 2.7e-10 41.0 1.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Kelch_3 PF13415.6 ORY46878.1 - 7e-28 96.3 8.4 2.9e-05 24.2 0.0 6.9 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.25 ORY46878.1 - 1.2e-26 92.0 2.4 4.6e-08 32.5 0.0 5.8 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.6 ORY46878.1 - 8e-25 86.6 8.5 5.6e-13 48.7 0.0 6.1 6 2 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY46878.1 - 2.2e-21 74.9 4.4 1.1e-06 28.3 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 ORY46878.1 - 4.8e-20 71.1 4.2 5.3e-06 26.5 0.1 5.7 5 1 1 6 6 6 4 Kelch motif Kelch_5 PF13854.6 ORY46878.1 - 1.8e-18 66.1 0.3 0.00048 20.0 0.0 5.5 5 0 0 5 5 5 5 Kelch motif DJ-1_PfpI PF01965.24 ORY46879.1 - 5.2e-50 169.5 0.4 6e-50 169.3 0.4 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORY46879.1 - 0.00018 21.3 0.0 0.00044 20.0 0.0 1.6 1 1 1 2 2 2 1 ThiJ/PfpI family-like GATase_3 PF07685.14 ORY46879.1 - 0.2 11.2 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Glyco_hydro_cc PF11790.8 ORY46880.1 - 0.34 10.5 2.9 0.46 10.0 0.2 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase catalytic core OAD_gamma PF04277.13 ORY46880.1 - 8.7 7.0 7.1 1.1 9.9 1.7 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain TBP PF00352.21 ORY46881.1 - 3.2e-67 222.5 0.1 1.5e-32 111.4 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 ORY46881.1 - 4e-05 23.6 0.0 0.17 12.0 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 ORY46881.1 - 0.026 14.3 0.3 0.083 12.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4295) Hep_59 PF07052.11 ORY46882.1 - 1.4e-09 38.6 0.8 2.9e-09 37.6 0.1 1.8 2 0 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 E1-E2_ATPase PF00122.20 ORY46883.1 - 3.8e-43 147.1 0.5 3.8e-43 147.1 0.5 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 ORY46883.1 - 1.7e-21 76.0 0.0 3.9e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 ORY46883.1 - 5.5e-18 65.3 7.5 7.6e-14 51.8 4.1 3.0 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY46883.1 - 9.1e-16 58.8 0.0 1.7e-13 51.4 0.0 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY46883.1 - 4.5e-15 55.1 0.0 1.2e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY46883.1 - 0.0062 16.3 0.3 0.045 13.5 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORY46884.1 - 1.1e-46 158.7 1.2 1.1e-46 158.7 1.2 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY46884.1 - 2.5e-19 69.7 12.9 1.8e-15 57.1 4.1 3.0 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORY46884.1 - 6.2e-19 67.9 0.0 1.3e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY46884.1 - 8e-19 68.8 0.0 1.5e-16 61.4 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY46884.1 - 1e-13 50.7 0.0 3.5e-13 49.0 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY46884.1 - 0.0024 17.7 0.6 0.44 10.2 0.3 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase RRP14 PF15459.6 ORY46884.1 - 0.19 12.3 0.1 1.1 9.9 0.0 2.3 3 0 0 3 3 3 0 60S ribosome biogenesis protein Rrp14 zf-MYND PF01753.18 ORY46885.1 - 2.1e-06 27.7 18.8 3.8e-06 26.9 18.8 1.4 1 0 0 1 1 1 1 MYND finger Mg_trans_NIPA PF05653.14 ORY46886.1 - 4.2e-24 85.2 12.3 5.6e-24 84.8 12.3 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORY46886.1 - 2.8e-07 30.8 27.2 1.4e-06 28.5 1.4 3.3 2 2 1 3 3 3 3 EamA-like transporter family DUF2374 PF09574.10 ORY46886.1 - 2 8.3 6.9 14 5.6 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (Duf2374) LRR_6 PF13516.6 ORY46887.1 - 1e-19 68.8 18.8 1.3e-05 24.8 0.3 7.1 7 0 0 7 7 7 5 Leucine Rich repeat LRR_1 PF00560.33 ORY46887.1 - 5.9e-08 32.2 2.5 1.8 9.4 0.1 5.5 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_4 PF12799.7 ORY46887.1 - 1.1e-06 28.9 1.7 0.0018 18.7 0.2 4.2 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY46887.1 - 0.0052 16.5 13.2 0.042 13.6 2.6 4.4 3 2 1 4 4 4 2 Leucine rich repeat LRR_2 PF07723.13 ORY46887.1 - 0.024 15.3 0.0 2.7 8.8 0.0 3.0 3 0 0 3 3 3 0 Leucine Rich Repeat Rep_fac_C PF08542.11 ORY46889.1 - 1.7e-21 76.4 0.0 4.4e-21 75.1 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 ORY46889.1 - 6.6e-13 49.2 0.0 9.9e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 ORY46889.1 - 7.6e-13 48.6 0.0 2.7e-10 40.3 0.3 2.3 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 ORY46889.1 - 2.7e-07 30.7 0.0 5.5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY46889.1 - 3e-06 27.7 0.0 0.00028 21.3 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY46889.1 - 8.1e-06 26.1 0.0 0.028 14.7 0.0 2.3 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 ORY46889.1 - 2e-05 24.4 0.0 4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 ORY46889.1 - 6.2e-05 22.8 0.0 0.00014 21.7 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 ORY46889.1 - 0.00029 20.8 0.0 0.00085 19.3 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_24 PF13479.6 ORY46889.1 - 0.00033 20.4 0.0 0.00056 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ORY46889.1 - 0.00033 20.1 0.0 0.0042 16.5 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 ORY46889.1 - 0.0019 18.1 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY46889.1 - 0.0022 18.3 0.0 0.016 15.6 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.11 ORY46889.1 - 0.0023 17.8 0.0 0.0041 17.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 ORY46889.1 - 0.0035 16.8 0.0 1.1 8.6 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein Cytomega_gL PF01801.16 ORY46889.1 - 0.0052 16.2 0.0 0.0072 15.7 0.0 1.2 1 0 0 1 1 1 1 Cytomegalovirus glycoprotein L NTPase_1 PF03266.15 ORY46889.1 - 0.012 15.5 0.1 0.036 14.0 0.0 1.8 1 1 1 2 2 2 0 NTPase ABC_tran PF00005.27 ORY46889.1 - 0.016 15.7 0.0 0.039 14.5 0.0 1.5 1 1 0 1 1 1 0 ABC transporter MeaB PF03308.16 ORY46889.1 - 0.02 13.9 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 ORY46889.1 - 0.021 14.8 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 ORY46889.1 - 0.028 14.0 0.0 0.15 11.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 ORY46889.1 - 0.048 13.9 0.0 0.094 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORY46889.1 - 0.05 14.2 0.0 0.092 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY46889.1 - 0.055 13.9 0.0 0.17 12.3 0.0 2.0 1 1 0 1 1 1 0 RNA helicase AAA_assoc_2 PF16193.5 ORY46889.1 - 0.057 13.8 0.0 0.21 12.0 0.0 2.0 2 0 0 2 2 1 0 AAA C-terminal domain AAA_30 PF13604.6 ORY46889.1 - 0.063 13.0 0.0 0.17 11.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ORY46889.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF5119 PF17145.4 ORY46889.1 - 0.15 12.0 0.0 9.4 6.1 0.0 2.4 3 0 0 3 3 2 0 Domain of unknown function (DUF5119) AMP-binding PF00501.28 ORY46890.1 - 1.8e-58 198.1 0.0 3.5e-58 197.2 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme NUDIX PF00293.28 ORY46891.1 - 3.6e-09 36.8 0.0 5.2e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Motile_Sperm PF00635.26 ORY46893.1 - 1.1e-20 73.5 0.0 1.7e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 MSP (Major sperm protein) domain UPF0172 PF03665.13 ORY46894.1 - 2.5e-41 141.9 0.0 3e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) MFS_1 PF07690.16 ORY46897.1 - 1.1e-18 67.4 53.2 1.6e-17 63.5 53.2 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily AAA_22 PF13401.6 ORY46897.1 - 0.00073 19.8 0.0 0.0019 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Peptidase_S13 PF02113.15 ORY46897.1 - 0.12 11.1 0.1 0.19 10.4 0.1 1.2 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family R_equi_Vir PF05526.11 ORY46897.1 - 1.1 9.1 4.4 0.32 10.8 1.2 1.7 2 0 0 2 2 2 0 Rhodococcus equi virulence-associated protein TFIIF_alpha PF05793.12 ORY46898.1 - 2.4e-09 36.3 33.7 0.0046 15.6 0.0 3.3 2 1 0 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PBP1_TM PF14812.6 ORY46898.1 - 2.1 8.7 14.9 4.6 7.7 3.8 3.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PKI PF02827.16 ORY46898.1 - 2.5 8.4 5.0 4.4 7.6 0.0 3.2 2 1 1 3 3 3 0 cAMP-dependent protein kinase inhibitor Herpes_BLRF2 PF05812.12 ORY46898.1 - 3.8 7.7 9.4 1.9 8.6 0.2 3.1 2 1 0 2 2 2 0 Herpesvirus BLRF2 protein Peptidase_C12 PF01088.21 ORY46900.1 - 2.8e-26 92.6 0.0 3.1e-26 92.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Peptidase_C12 PF01088.21 ORY46901.1 - 3.3e-19 69.5 0.0 3.8e-19 69.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 ANF_receptor PF01094.28 ORY46903.1 - 3.9e-18 65.7 0.0 5.1e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY46903.1 - 2.3e-13 50.6 0.1 3.6e-13 49.9 0.1 1.4 1 1 0 1 1 1 1 Periplasmic binding protein 7tm_3 PF00003.22 ORY46904.1 - 6.2e-06 26.1 12.1 7.9e-06 25.8 12.1 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR PH PF00169.29 ORY46906.1 - 0.00082 19.9 0.0 0.0015 19.0 0.0 1.5 1 0 0 1 1 1 1 PH domain PH PF00169.29 ORY46907.1 - 0.0009 19.7 0.0 0.0017 18.8 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF4736 PF15883.5 ORY46907.1 - 4.2 7.1 8.3 7.8 6.2 1.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4736) Clr2_transil PF16761.5 ORY46909.1 - 4e-15 56.4 0.0 9.1e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 V_ATPase_I PF01496.19 ORY46909.1 - 0.35 8.7 1.8 0.48 8.3 1.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UQ_con PF00179.26 ORY46910.1 - 1.8e-47 160.5 0.2 2e-47 160.3 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY46910.1 - 0.0049 17.1 0.6 0.013 15.7 0.6 1.8 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 ORY46910.1 - 0.013 15.2 0.0 0.016 14.9 0.0 1.3 1 1 0 1 1 1 0 Prokaryotic E2 family B CoA_trans PF01144.23 ORY46911.1 - 7.2e-115 381.9 5.4 2e-70 236.6 1.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 ORY46911.1 - 0.00025 21.0 0.0 0.00051 20.0 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain SAE2 PF08573.10 ORY46913.1 - 2.1e-12 48.2 10.5 1.2e-09 39.2 4.0 3.3 2 1 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus IFT43 PF15305.6 ORY46913.1 - 0.59 10.3 9.2 12 6.0 9.2 2.4 1 1 0 1 1 1 0 Intraflagellar transport protein 43 MLANA PF14991.6 ORY46916.1 - 0.0065 16.7 0.0 0.017 15.4 0.0 1.7 2 0 0 2 2 2 1 Protein melan-A Clusterin PF01093.17 ORY46916.1 - 0.03 13.4 0.4 0.043 12.9 0.4 1.2 1 0 0 1 1 1 0 Clusterin TTL PF03133.15 ORY46917.1 - 7.8e-49 166.4 0.8 2e-32 112.5 0.3 2.2 1 1 1 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 ORY46917.1 - 2e-06 27.3 0.0 0.0002 20.7 0.0 2.6 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_3 PF02655.14 ORY46917.1 - 0.018 15.1 0.0 2.5 8.1 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_ST PF14397.6 ORY46917.1 - 0.13 11.4 0.0 0.3 10.3 0.0 1.5 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp zf-C2H2 PF00096.26 ORY46918.1 - 3.2e-38 128.1 65.5 0.00026 21.3 0.3 11.3 11 0 0 11 11 11 11 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY46918.1 - 9.4e-26 88.3 67.0 0.0067 17.2 0.1 11.4 11 0 0 11 11 11 9 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY46918.1 - 6.7e-22 76.9 51.5 0.00017 21.8 1.6 10.8 11 0 0 11 11 10 7 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY46918.1 - 4.3e-10 39.3 44.6 0.022 14.7 0.3 11.5 11 1 1 12 12 12 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY46918.1 - 4.7e-05 23.6 21.5 0.53 10.6 0.0 7.1 8 0 0 8 8 6 2 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 ORY46918.1 - 0.00047 20.3 12.4 0.92 9.6 0.7 5.6 5 1 1 6 6 6 2 Aberrant zinc-finger zf_C2H2_ZHX PF18387.1 ORY46918.1 - 0.0024 17.5 17.4 0.026 14.2 0.8 5.0 3 1 2 5 5 5 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_3rep PF18868.1 ORY46918.1 - 0.018 15.7 22.8 0.062 14.0 6.2 5.6 3 2 2 6 6 5 0 Zinc finger C2H2-type, 3 repeats zf-Di19 PF05605.12 ORY46918.1 - 0.034 14.4 1.5 0.034 14.4 1.5 6.9 7 1 0 8 8 7 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 ORY46918.1 - 0.13 12.7 0.1 0.13 12.7 0.1 8.2 9 0 0 9 9 8 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 ORY46918.1 - 0.14 12.3 21.6 3.7 7.8 0.4 7.4 9 0 0 9 9 9 0 Zinc ribbon domain zf_UBZ PF18439.1 ORY46918.1 - 0.49 10.0 10.3 69 3.1 0.1 5.5 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-LYAR PF08790.11 ORY46918.1 - 2.3 8.2 14.2 10 6.1 0.0 6.0 7 0 0 7 7 7 0 LYAR-type C2HC zinc finger C1_4 PF07975.12 ORY46918.1 - 2.8 8.2 13.2 2.2 8.6 1.0 5.2 4 1 1 5 5 5 0 TFIIH C1-like domain Zn-C2H2_12 PF18112.1 ORY46918.1 - 3.3 8.3 7.2 11 6.6 1.1 4.3 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain An_peroxidase PF03098.15 ORY46919.1 - 5.6e-114 381.6 0.0 7.9e-114 381.1 0.0 1.2 1 0 0 1 1 1 1 Animal haem peroxidase DOMON PF03351.17 ORY46919.1 - 7e-18 65.0 0.1 1.9e-17 63.6 0.1 1.8 1 0 0 1 1 1 1 DOMON domain Cyt-b5 PF00173.28 ORY46919.1 - 1.8e-09 37.6 0.0 4.1e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.24 ORY46919.1 - 3.9e-08 33.6 0.0 9.1e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain DUF4088 PF13317.6 ORY46919.1 - 0.08 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) Cytochrom_B561 PF03188.16 ORY46919.1 - 0.14 12.3 4.9 0.26 11.4 4.9 1.4 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 Eaf7 PF07904.13 ORY46920.1 - 1.6e-12 47.7 0.1 4.7e-12 46.2 0.0 1.8 2 1 0 2 2 2 1 Chromatin modification-related protein EAF7 UPF0524 PF15823.5 ORY46920.1 - 0.17 11.3 2.1 0.24 10.7 2.1 1.3 1 0 0 1 1 1 0 UPF0524 of C3orf70 TMEM171 PF15471.6 ORY46920.1 - 5.5 5.9 5.7 7.7 5.4 5.7 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 GDA1_CD39 PF01150.17 ORY46921.1 - 1.7e-63 214.7 0.0 2e-62 211.2 0.0 2.4 1 1 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Bestrophin PF01062.21 ORY46922.1 - 7.1e-40 137.2 0.1 1e-39 136.7 0.1 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel DUF1295 PF06966.12 ORY46922.1 - 0.0079 15.7 0.2 0.019 14.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Bestrophin PF01062.21 ORY46923.1 - 1e-29 103.9 2.4 2.5e-17 63.2 0.2 2.1 1 1 1 2 2 2 2 Bestrophin, RFP-TM, chloride channel Pkinase PF00069.25 ORY46924.1 - 2.8e-24 85.9 0.0 1.2e-14 54.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY46924.1 - 3.6e-08 33.0 0.0 2.4e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PAS_12 PF18095.1 ORY46924.1 - 0.13 11.9 0.0 0.35 10.5 0.0 1.6 1 1 1 2 2 2 0 UPF0242 C-terminal PAS-like domain Histone PF00125.24 ORY46925.1 - 4.7e-18 65.8 0.3 6.1e-18 65.4 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PP1_bind PF15276.6 ORY46925.1 - 0.56 10.6 4.4 1.6 9.1 2.7 2.1 1 1 1 2 2 2 0 Protein phosphatase 1 binding EF-hand_7 PF13499.6 ORY46926.1 - 3.7e-12 46.5 0.3 3.4e-08 33.8 0.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY46926.1 - 2.9e-09 36.1 0.2 0.00098 18.9 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 ORY46926.1 - 2e-06 26.9 1.2 0.042 13.4 0.0 3.1 4 0 0 4 4 4 2 EF hand EFhand_Ca_insen PF08726.10 ORY46926.1 - 0.001 19.1 0.5 0.0015 18.5 0.5 1.3 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_9 PF14658.6 ORY46926.1 - 0.0087 16.4 0.1 0.15 12.4 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 ORY46926.1 - 0.021 14.7 1.2 0.064 13.1 0.4 2.2 3 1 0 3 3 3 0 EF-hand domain pair DHR10 PF18595.1 ORY46927.1 - 0.022 14.8 0.6 0.046 13.8 0.6 1.5 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain DUF4611 PF15387.6 ORY46927.1 - 0.028 14.6 5.0 0.11 12.7 5.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Sec34 PF04136.15 ORY46927.1 - 0.52 10.2 3.6 11 5.9 0.2 2.8 3 0 0 3 3 3 0 Sec34-like family CENP-B_dimeris PF09026.10 ORY46927.1 - 1.4 9.4 8.0 3.4 8.1 8.0 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BTB PF00651.31 ORY46928.1 - 5.8e-15 55.5 0.0 8.6e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain TLD PF07534.16 ORY46928.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 TLD DUF2418 PF10332.9 ORY46929.1 - 4.4e-15 56.0 0.8 1.1e-14 54.7 0.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) zf-RING_2 PF13639.6 ORY46930.1 - 6.4e-13 48.8 6.2 8.9e-13 48.3 6.2 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 ORY46930.1 - 4.9e-09 36.3 8.4 1.3e-08 35.0 8.5 1.6 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORY46930.1 - 3.8e-08 33.0 5.7 6.5e-08 32.3 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY46930.1 - 1.5e-06 27.8 7.3 2.6e-06 27.1 5.2 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 ORY46930.1 - 2.8e-06 27.1 5.0 4.4e-06 26.5 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY46930.1 - 8.8e-06 25.5 3.6 1.4e-05 24.8 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORY46930.1 - 1.5e-05 25.0 2.1 2.3e-05 24.3 2.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 ORY46930.1 - 2.2e-05 24.4 2.2 2.6e-05 24.2 0.8 1.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY46930.1 - 2.5e-05 24.1 4.1 3.7e-05 23.6 4.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 ORY46930.1 - 0.002 17.9 4.1 0.0031 17.3 4.1 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 ORY46930.1 - 0.003 17.7 3.3 0.0062 16.7 3.3 1.5 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 ORY46930.1 - 0.0049 16.7 8.0 0.63 10.0 8.1 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 ORY46930.1 - 0.0084 16.0 7.5 0.097 12.6 4.4 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 Rad50_zn_hook PF04423.14 ORY46930.1 - 0.013 15.4 2.0 0.77 9.7 0.2 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif TerY_C PF15616.6 ORY46930.1 - 0.015 15.4 0.8 0.032 14.3 0.8 1.5 1 1 0 1 1 1 0 TerY-C metal binding domain Tmemb_55A PF09788.9 ORY46930.1 - 0.043 12.9 0.3 0.058 12.5 0.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 55A FANCL_C PF11793.8 ORY46930.1 - 0.053 13.7 7.9 1.2 9.3 7.9 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_10 PF16685.5 ORY46930.1 - 0.055 13.6 3.3 0.11 12.6 3.3 1.5 1 1 0 1 1 1 0 zinc RING finger of MSL2 RINGv PF12906.7 ORY46930.1 - 0.073 13.2 3.5 0.14 12.3 3.5 1.5 1 1 0 1 1 1 0 RING-variant domain zinc-ribbons_6 PF07191.12 ORY46930.1 - 0.14 12.1 2.6 0.23 11.4 2.6 1.3 1 0 0 1 1 1 0 zinc-ribbons DUF1272 PF06906.11 ORY46930.1 - 0.19 11.8 2.4 0.32 11.1 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Zn_ribbon_17 PF17120.5 ORY46930.1 - 0.33 10.6 6.6 0.66 9.6 6.6 1.4 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 ORY46930.1 - 0.4 10.6 6.1 1.3 8.9 6.3 1.7 1 1 1 2 2 2 0 PHD-finger zf-WRNIP1_ubi PF18279.1 ORY46930.1 - 0.49 11.2 3.5 14 6.6 0.5 2.7 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-Nse PF11789.8 ORY46930.1 - 1.2 9.0 6.6 3.8 7.4 6.6 1.8 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_5 PF17121.5 ORY46930.1 - 3.9 7.4 6.6 62 3.6 6.4 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) An_peroxidase PF03098.15 ORY46931.1 - 6.2e-81 272.6 0.0 7.4e-81 272.3 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Cyt-b5 PF00173.28 ORY46932.1 - 2.7e-08 33.8 0.0 6.5e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_6 PF00970.24 ORY46932.1 - 4.4e-08 33.4 0.0 9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ORY46932.1 - 1.5e-07 32.1 0.0 3.6e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DOMON PF03351.17 ORY46932.1 - 9.8e-07 29.0 0.0 2.5e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 ORY46932.1 - 9.6e-06 25.8 11.0 1.7e-05 25.0 11.0 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 NAD_binding_6 PF08030.12 ORY46932.1 - 0.17 12.0 0.0 0.34 11.0 0.0 1.5 1 0 0 1 1 1 0 Ferric reductase NAD binding domain Rep_fac-A_C PF08646.10 ORY46934.1 - 0.0098 15.6 0.0 0.012 15.3 0.0 1.3 1 1 0 1 1 1 1 Replication factor-A C terminal domain zinc-ribbons_6 PF07191.12 ORY46934.1 - 0.068 13.2 0.8 0.12 12.4 0.8 1.3 1 0 0 1 1 1 0 zinc-ribbons IlvGEDA_leader PF08046.11 ORY46934.1 - 0.072 12.5 0.2 0.26 10.7 0.2 2.0 1 0 0 1 1 1 0 IlvGEDA operon leader peptide zinc_ribbon_2 PF13240.6 ORY46934.1 - 0.086 12.6 0.9 0.24 11.2 0.9 1.6 1 1 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 ORY46934.1 - 0.099 12.1 1.2 0.22 11.0 1.2 1.6 1 1 0 1 1 1 0 zinc-ribbon domain DNA_ligase_ZBD PF03119.16 ORY46934.1 - 0.16 12.0 1.3 0.44 10.6 1.3 1.9 1 1 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Tubulin PF00091.25 ORY46935.1 - 1.1e-27 97.6 0.0 1.8e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 ORY46935.1 - 0.078 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Pkinase PF00069.25 ORY46936.1 - 8.1e-27 94.2 0.0 5.4e-24 85.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY46936.1 - 4.3e-08 32.8 0.0 2.2e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY46936.1 - 0.0041 16.0 0.0 0.0059 15.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORY46936.1 - 0.022 14.1 0.0 0.061 12.7 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family THOC2_N PF16134.5 ORY46937.1 - 6.4e-98 329.0 0.0 7.1e-90 302.4 0.0 2.7 2 1 0 2 2 2 2 THO complex subunit 2 N-terminus Tho2 PF11262.8 ORY46937.1 - 8.1e-84 281.4 0.2 1.5e-83 280.4 0.2 1.5 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 NAD_binding_10 PF13460.6 ORY46937.1 - 2.8e-27 95.8 0.0 5.4e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Thoc2 PF11732.8 ORY46937.1 - 6.3e-19 67.8 0.0 2e-18 66.2 0.0 1.9 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Epimerase PF01370.21 ORY46937.1 - 0.0006 19.4 0.1 0.0011 18.5 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 ORY46937.1 - 0.0045 16.6 0.2 0.01 15.4 0.2 1.6 1 0 0 1 1 1 1 NmrA-like family Zn_clus PF00172.18 ORY46938.1 - 4.9e-07 29.8 25.8 0.0019 18.3 11.0 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY46938.1 - 0.00023 20.3 0.9 0.00088 18.4 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Pkinase PF00069.25 ORY46940.1 - 6.8e-28 97.8 0.0 8.3e-21 74.5 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY46940.1 - 1.8e-09 37.2 0.0 1.6e-08 34.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 ORY46940.1 - 0.068 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 ORY46940.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mg_trans_NIPA PF05653.14 ORY46941.1 - 1.2e-72 244.5 20.5 1.5e-72 244.2 20.5 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORY46941.1 - 0.0003 20.9 5.6 0.0003 20.9 5.6 4.4 3 1 0 3 3 3 1 EamA-like transporter family BCLP PF12304.8 ORY46941.1 - 0.017 14.7 5.5 0.26 10.8 0.4 2.6 2 0 0 2 2 2 0 Beta-casein like protein HR_lesion PF05514.11 ORY46941.1 - 0.029 14.5 1.0 1.2 9.3 0.0 2.5 2 1 0 2 2 2 0 HR-like lesion-inducing Gram_pos_anchor PF00746.21 ORY46941.1 - 0.067 13.1 1.2 13 5.8 0.0 2.9 2 0 0 2 2 2 0 LPXTG cell wall anchor motif TMEM234 PF10639.9 ORY46941.1 - 1.3 9.1 8.8 0.54 10.3 0.9 2.4 2 0 0 2 2 2 0 Putative transmembrane family 234 DUF2871 PF11070.8 ORY46941.1 - 2.5 8.4 10.0 0.074 13.3 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2871) DUF4605 PF15378.6 ORY46941.1 - 8.1 6.4 10.7 1.9 8.4 2.5 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4605) Mg_trans_NIPA PF05653.14 ORY46942.1 - 5.8e-74 248.9 16.4 6.8e-74 248.6 16.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORY46942.1 - 0.0018 18.5 4.5 0.0018 18.5 4.5 3.9 3 1 0 3 3 3 1 EamA-like transporter family B12D PF06522.11 ORY46942.1 - 0.18 11.6 3.1 0.27 11.0 1.0 2.4 1 1 1 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF996 PF06195.13 ORY46942.1 - 2.7 8.3 10.2 2.4 8.4 1.5 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF996) Neurensin PF14927.6 ORY46942.1 - 4.2 7.1 6.5 4.3 7.1 0.0 2.8 3 0 0 3 3 3 0 Neurensin Pkinase PF00069.25 ORY46943.1 - 4.2e-17 62.4 0.0 6.8e-16 58.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 ORY46944.1 - 9.2e-32 110.4 0.0 2.1e-24 86.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY46944.1 - 2.5e-10 40.1 0.0 4.3e-10 39.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY46944.1 - 0.0012 18.2 0.2 0.0019 17.6 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 ORY46945.1 - 1.5e-20 73.7 0.0 2e-11 43.8 0.1 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY46945.1 - 3.7e-10 39.5 0.0 1.3e-09 37.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY46945.1 - 4.5e-05 22.9 0.2 6.9e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 ORY46946.1 - 1.8e-26 93.1 0.0 2.5e-18 66.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY46946.1 - 6.6e-16 58.4 0.0 1.1e-15 57.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY46946.1 - 0.0099 15.3 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Exo84_C PF16528.5 ORY46947.1 - 1.8e-33 116.1 0.3 1.8e-33 116.1 0.3 2.5 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 ORY46947.1 - 7.2e-06 26.0 0.5 2.4e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Vps51/Vps67 DUF3388 PF11868.8 ORY46947.1 - 0.039 13.3 0.7 0.7 9.2 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3388) Sec3-PIP2_bind PF15277.6 ORY46947.1 - 0.075 13.2 0.8 0.16 12.1 0.8 1.5 1 0 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH TFIID-31kDa PF02291.15 ORY46948.1 - 6.7e-26 90.8 0.0 8.3e-26 90.5 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORY46948.1 - 1.1e-09 38.1 0.0 1.6e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.6 ORY46948.1 - 6.6e-07 29.6 0.1 9.9e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORY46948.1 - 0.0022 18.1 0.0 0.0026 17.9 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 ORY46948.1 - 0.02 15.2 0.0 0.024 15.0 0.0 1.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TAF PF02969.17 ORY46948.1 - 0.042 14.0 0.0 0.056 13.6 0.0 1.1 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Inhibitor_I42 PF09394.10 ORY46949.1 - 3.5e-12 46.6 0.0 4.8e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 Inhibitor_I42 PF09394.10 ORY46950.1 - 8.4e-14 51.8 0.1 1.2e-13 51.3 0.1 1.1 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 Inhibitor_I42 PF09394.10 ORY46951.1 - 2.3e-09 37.5 0.0 3.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 Homeodomain PF00046.29 ORY46951.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Homeodomain Inhibitor_I42 PF09394.10 ORY46952.1 - 1.5e-12 47.8 0.1 2e-12 47.3 0.1 1.1 1 0 0 1 1 1 1 Chagasin family peptidase inhibitor I42 Sec8_exocyst PF04048.14 ORY46953.1 - 5.3e-34 117.1 1.8 2.5e-33 114.9 1.8 2.3 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 ORY46953.1 - 7.1e-07 28.8 0.5 2.8e-06 26.9 0.5 2.0 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex NAGidase PF07555.13 ORY46953.1 - 0.0061 15.9 0.6 0.29 10.4 0.2 2.5 3 0 0 3 3 3 1 beta-N-acetylglucosaminidase DUF5344 PF17279.2 ORY46953.1 - 0.0072 16.9 2.1 0.024 15.2 0.1 3.3 3 0 0 3 3 3 1 Family of unknown function (DUF5344) KxDL PF10241.9 ORY46953.1 - 0.14 12.4 0.9 0.54 10.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein ER PF01133.17 ORY46953.1 - 0.34 10.9 2.7 4.5 7.3 0.2 3.7 3 1 0 3 3 3 0 Enhancer of rudimentary Adaptin_N PF01602.20 ORY46954.1 - 5.3e-105 352.0 2.8 6.9e-105 351.6 2.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ORY46954.1 - 9.9e-14 51.7 3.1 8e-13 48.7 0.3 3.7 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORY46954.1 - 0.00054 20.3 4.6 0.31 11.4 0.0 4.9 5 1 1 6 6 6 1 HEAT repeats HEAT PF02985.22 ORY46954.1 - 0.0008 19.5 1.3 23 5.6 0.0 5.7 6 0 0 6 6 6 2 HEAT repeat EP400_N PF15790.5 ORY46954.1 - 0.56 9.0 7.3 0.27 10.0 5.1 1.5 1 1 0 1 1 1 0 E1A-binding protein p400, N-terminal Fis1_TPR_C PF14853.6 ORY46955.1 - 2.3e-22 78.8 0.7 4.2e-22 78.0 0.7 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 ORY46955.1 - 9.8e-08 31.5 0.0 1.8e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_19 PF14559.6 ORY46955.1 - 0.04 14.4 0.7 4.3 7.9 0.4 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY46957.1 - 3.1e-18 64.7 6.2 4.4e-06 26.3 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY46957.1 - 3.2e-13 48.7 2.0 0.00075 19.4 0.1 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY46957.1 - 8.1e-10 38.1 0.8 0.05 13.8 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORY46957.1 - 1.5e-08 34.2 0.1 0.0066 16.1 0.1 2.7 2 0 0 2 2 2 2 TPR repeat CS PF04969.16 ORY46957.1 - 1.3e-07 32.6 0.0 7.7e-07 30.0 0.0 2.3 2 0 0 2 2 2 1 CS domain TPR_12 PF13424.6 ORY46957.1 - 0.00044 20.5 0.8 0.5 10.7 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY46957.1 - 0.0011 19.2 1.8 0.0035 17.5 0.1 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 ORY46957.1 - 0.0021 18.7 0.1 0.42 11.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY46957.1 - 0.0022 18.7 0.0 0.65 11.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY46957.1 - 0.0056 16.6 2.1 2.4 8.4 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY46957.1 - 0.0098 16.4 1.0 3.3 8.3 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORY46957.1 - 0.01 15.9 0.0 15 5.8 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY46957.1 - 0.078 13.1 0.2 19 5.4 0.0 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat IML1 PF12257.8 ORY46957.1 - 0.26 10.4 3.2 0.12 11.4 1.0 1.5 2 0 0 2 2 2 0 Vacuolar membrane-associated protein Iml1 DUF3713 PF12506.8 ORY46957.1 - 3 8.2 9.5 0.1 12.9 0.7 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF3713) ORMDL PF04061.14 ORY46958.1 - 2e-49 166.9 2.3 2.3e-49 166.7 2.3 1.0 1 0 0 1 1 1 1 ORMDL family MFS_1 PF07690.16 ORY46959.1 - 5e-25 88.2 75.7 2.5e-17 62.8 34.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_Dp1 PF16938.5 ORY46959.1 - 0.022 15.0 1.1 0.14 12.4 1.1 2.4 1 0 0 1 1 1 0 Putative phage holin Dp-1 Glyco_hydro_62 PF03664.13 ORY46959.1 - 0.023 14.0 0.1 0.023 14.0 0.1 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 62 MFS_1 PF07690.16 ORY46960.1 - 3.7e-27 95.2 53.1 3e-20 72.4 27.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2458 PF10454.9 ORY46961.1 - 1.5e-08 34.5 6.5 1.5e-08 34.5 6.5 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF2458) DGCR6 PF07324.11 ORY46961.1 - 1.5e-05 24.7 3.0 1.5e-05 24.7 3.0 2.4 2 1 0 2 2 2 1 DiGeorge syndrome critical region 6 (DGCR6) protein ATP_transf PF09830.9 ORY46961.1 - 0.078 13.1 0.1 0.2 11.8 0.1 1.7 1 0 0 1 1 1 0 ATP adenylyltransferase TBPIP PF07106.13 ORY46962.1 - 4.9e-23 80.8 0.1 4.9e-23 80.8 0.1 2.3 3 0 0 3 3 3 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 ORY46962.1 - 2.7e-06 27.4 3.1 6.3e-06 26.2 3.1 1.7 1 0 0 1 1 1 1 Leucine zipper with capping helix domain FlxA PF14282.6 ORY46962.1 - 0.0092 16.0 1.8 0.018 15.0 1.8 1.5 1 0 0 1 1 1 1 FlxA-like protein Penicillinase_R PF03965.16 ORY46962.1 - 0.013 15.9 0.4 0.025 14.9 0.1 1.8 2 1 0 2 2 2 0 Penicillinase repressor DUF4335 PF14233.6 ORY46962.1 - 0.024 14.5 0.9 0.033 14.1 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) PhetRS_B1 PF18262.1 ORY46962.1 - 0.06 13.6 0.9 0.28 11.4 0.0 2.4 2 1 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain TolA_bind_tri PF16331.5 ORY46962.1 - 0.074 13.1 2.9 1.2 9.3 0.7 2.4 1 1 1 2 2 2 0 TolA binding protein trimerisation DUF724 PF05266.14 ORY46962.1 - 0.33 10.8 6.8 0.078 12.8 3.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Atg14 PF10186.9 ORY46962.1 - 0.35 9.9 5.4 0.46 9.5 5.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PRKG1_interact PF15898.5 ORY46962.1 - 0.88 10.5 9.0 0.37 11.7 5.6 2.0 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain ZapB PF06005.12 ORY46962.1 - 0.96 9.9 8.6 85 3.7 10.2 2.8 2 1 0 2 2 2 0 Cell division protein ZapB DUF4407 PF14362.6 ORY46962.1 - 1.6 8.0 10.3 2.3 7.5 10.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) GrpE PF01025.19 ORY46962.1 - 8.7 6.0 11.3 6.6e+02 -0.1 11.3 2.8 1 1 0 1 1 1 0 GrpE ECH_1 PF00378.20 ORY46963.1 - 8.3e-19 67.9 0.0 1e-18 67.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY46963.1 - 9.6e-09 35.2 0.0 1.2e-08 34.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Na_H_antiport_2 PF13726.6 ORY46963.1 - 0.012 15.7 2.1 0.082 13.1 0.1 2.3 2 1 0 2 2 2 0 Na+-H+ antiporter family DUF680 PF05079.12 ORY46964.1 - 0.012 16.3 0.3 0.048 14.4 0.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF680) Ribosomal_L44 PF00935.19 ORY46966.1 - 5.1e-37 126.2 8.9 5.1e-37 126.2 8.9 2.0 2 0 0 2 2 2 1 Ribosomal protein L44 zf-CHY PF05495.12 ORY46967.1 - 8.9e-14 51.7 12.6 1.9e-13 50.7 12.6 1.5 1 1 0 1 1 1 1 CHY zinc finger Zn-ribbon_8 PF09723.10 ORY46967.1 - 0.0026 17.9 11.9 0.0035 17.4 3.0 2.3 2 0 0 2 2 2 1 Zinc ribbon domain zf_UBZ PF18439.1 ORY46967.1 - 0.0028 17.2 4.9 1.3 8.6 0.1 3.2 3 0 0 3 3 3 2 Ubiquitin-Binding Zinc Finger Cys_rich_KTR PF14205.6 ORY46967.1 - 0.0089 15.8 9.4 0.13 12.1 2.2 2.4 1 1 1 2 2 2 2 Cysteine-rich KTR Zn_Tnp_IS1595 PF12760.7 ORY46967.1 - 0.01 15.8 8.2 0.19 11.7 5.3 2.4 2 1 0 2 2 2 0 Transposase zinc-ribbon domain C1_4 PF07975.12 ORY46967.1 - 0.011 16.0 13.3 0.099 12.9 0.4 3.1 1 1 2 3 3 3 0 TFIIH C1-like domain zf-TFIIB PF13453.6 ORY46967.1 - 0.015 14.7 3.7 0.33 10.3 1.0 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger HypA PF01155.19 ORY46967.1 - 0.027 14.5 1.5 0.027 14.5 1.5 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TF_Zn_Ribbon PF08271.12 ORY46967.1 - 0.073 12.6 7.7 3.7 7.1 0.5 2.8 2 1 1 3 3 3 0 TFIIB zinc-binding zf_Rg PF17915.1 ORY46967.1 - 0.099 12.1 3.2 3.8 7.0 0.2 2.5 2 1 0 2 2 2 0 Reverse gyrase zinc finger DUF3797 PF12677.7 ORY46967.1 - 0.1 12.5 0.1 0.1 12.5 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3797) Zn_ribbon_SprT PF17283.2 ORY46967.1 - 0.34 10.9 11.3 0.11 12.4 1.5 2.7 3 1 0 3 3 3 0 SprT-like zinc ribbon domain zf-ribbon_3 PF13248.6 ORY46967.1 - 0.41 10.1 10.9 1.4 8.5 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_4 PF13717.6 ORY46967.1 - 0.81 9.7 17.0 5.4 7.0 6.7 3.4 2 1 0 2 2 2 0 zinc-ribbon domain RecQ_Zn_bind PF16124.5 ORY46967.1 - 0.87 10.4 7.9 1.5 9.6 7.9 1.3 1 1 0 1 1 1 0 RecQ zinc-binding Zn_Tnp_IS91 PF14319.6 ORY46967.1 - 1 9.4 11.0 4.5 7.4 7.0 2.2 1 1 1 2 2 2 0 Transposase zinc-binding domain NOB1_Zn_bind PF08772.11 ORY46967.1 - 1.2 9.4 8.0 0.12 12.5 2.8 1.9 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Ribosomal_L37ae PF01780.19 ORY46967.1 - 1.5 8.9 6.9 1.1 9.4 3.6 1.9 1 1 1 2 2 2 0 Ribosomal L37ae protein family DpnI PF06044.12 ORY46967.1 - 2.2 7.9 7.7 5.4 6.6 0.2 2.0 1 1 1 2 2 2 0 Dam-replacing family zf-C2H2 PF00096.26 ORY46967.1 - 2.5 8.8 10.7 1.7 9.2 0.8 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type Evr1_Alr PF04777.13 ORY46967.1 - 3 8.4 7.7 22 5.6 7.8 2.2 1 1 1 2 2 2 0 Erv1 / Alr family OrfB_Zn_ribbon PF07282.11 ORY46967.1 - 4.5 7.3 10.6 0.63 10.0 3.7 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain P_C PF06640.11 ORY46968.1 - 2.8 8.0 10.4 4.6 7.3 4.3 2.2 2 0 0 2 2 2 0 P protein C-terminus RPA43_OB PF17875.1 ORY46969.1 - 5.7e-10 39.9 0.0 1.1e-09 39.0 0.0 1.4 1 1 0 1 1 1 1 RPA43 OB domain in RNA Pol I PhyH PF05721.13 ORY46971.1 - 1.6e-05 25.3 0.0 0.00012 22.4 0.0 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 ORY46971.1 - 0.041 12.6 0.0 2.1 7.0 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1479) DUF3090 PF11290.8 ORY46971.1 - 0.093 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) FAD_binding_3 PF01494.19 ORY46972.1 - 1.3e-21 77.3 0.1 1.8e-14 53.8 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ORY46972.1 - 1.2e-06 28.0 0.1 0.0014 17.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY46972.1 - 6.6e-05 23.1 0.0 0.00017 21.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ORY46972.1 - 0.00096 18.0 0.1 0.0074 15.0 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 ORY46972.1 - 0.0022 17.3 0.1 0.44 9.7 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY46972.1 - 0.0033 16.6 0.0 0.012 14.7 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 ORY46972.1 - 0.007 15.5 0.0 0.55 9.2 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 ORY46972.1 - 0.024 13.5 0.1 1.1 8.0 0.0 2.4 3 0 0 3 3 3 0 Tryptophan halogenase DAO PF01266.24 ORY46972.1 - 0.026 14.1 0.0 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 ORY46972.1 - 0.076 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.16 ORY46972.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SE PF08491.10 ORY46972.1 - 0.16 11.0 0.0 1.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase SH3_1 PF00018.28 ORY46973.1 - 2.2e-07 30.4 0.0 4.9e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY46973.1 - 0.0026 17.6 0.0 0.006 16.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_16 PF18348.1 ORY46973.1 - 0.0054 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial dipeptidyl-peptidase Sh3 domain RA PF00788.23 ORY46973.1 - 0.035 14.7 0.7 1.5 9.5 0.2 3.4 2 1 0 2 2 2 0 Ras association (RalGDS/AF-6) domain dbPDZ_assoc PF16610.5 ORY46973.1 - 0.91 9.8 12.2 3.4 8.0 12.2 2.0 1 0 0 1 1 1 0 Unstructured region between two PDZ domains on Dlg5 Thioredoxin PF00085.20 ORY46974.1 - 2.7e-53 178.3 0.2 1e-30 105.7 0.2 2.5 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 ORY46974.1 - 4.7e-16 59.5 5.0 4.7e-16 59.5 0.9 2.6 2 1 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 ORY46974.1 - 1.3e-15 57.5 0.0 1.1e-06 28.3 0.0 2.1 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 ORY46974.1 - 1.4e-11 44.8 0.1 4.4e-06 27.1 0.1 2.7 2 0 0 2 2 2 2 Thioredoxin-like domain HyaE PF07449.11 ORY46974.1 - 3.8e-06 26.8 0.0 0.015 15.2 0.0 2.5 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 ORY46974.1 - 1.2e-05 25.4 0.0 5.5e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.21 ORY46974.1 - 3.8e-05 23.6 0.2 0.00089 19.2 0.1 2.5 2 1 0 2 2 2 1 AhpC/TSA family Thioredoxin_6 PF13848.6 ORY46974.1 - 4.8e-05 23.3 1.2 0.017 15.0 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORY46974.1 - 0.00022 21.5 0.1 0.22 11.9 0.1 3.5 2 1 1 3 3 3 1 Thioredoxin-like TraF PF13728.6 ORY46974.1 - 0.0022 17.9 0.0 0.39 10.5 0.0 2.2 2 0 0 2 2 2 1 F plasmid transfer operon protein Redoxin PF08534.10 ORY46974.1 - 0.035 13.8 0.4 0.096 12.4 0.1 1.8 2 0 0 2 2 2 0 Redoxin DUF4921 PF16268.5 ORY46974.1 - 0.063 12.1 0.0 0.96 8.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4921) DDE_Tnp_1_2 PF13586.6 ORY46974.1 - 0.13 12.6 0.0 10 6.5 0.0 2.4 2 0 0 2 2 2 0 Transposase DDE domain DUF1574 PF07611.11 ORY46976.1 - 0.059 12.7 0.1 0.067 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) TPR_6 PF13174.6 ORY46976.1 - 0.36 11.6 0.2 0.36 11.6 0.2 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat CCSAP PF15748.5 ORY46976.1 - 4.1 7.5 9.9 12 6.0 9.9 1.7 1 1 0 1 1 1 0 Centriole, cilia and spindle-associated DsbD PF02683.15 ORY46977.1 - 2.9 7.7 11.4 0.3 10.9 4.2 2.5 1 1 1 2 2 2 0 Cytochrome C biogenesis protein transmembrane region FAD-oxidase_C PF02913.19 ORY46978.1 - 3.6e-60 203.7 0.0 5.7e-60 203.0 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 ORY46978.1 - 3.2e-36 124.1 1.0 5.3e-36 123.4 1.0 1.4 1 0 0 1 1 1 1 FAD binding domain Glyco_hydro_97 PF10566.9 ORY46978.1 - 0.018 14.3 0.0 0.032 13.5 0.0 1.3 1 0 0 1 1 1 0 Glycoside hydrolase 97 Herpes_UL49_5 PF05702.11 ORY46978.1 - 0.1 12.7 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein DEAD PF00270.29 ORY46979.1 - 1e-26 93.8 0.1 1.3e-25 90.2 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY46979.1 - 2.9e-23 82.3 0.0 5.5e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY46979.1 - 0.00015 21.8 0.0 0.0016 18.5 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ORY46979.1 - 0.013 14.8 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Ribosomal_S14 PF00253.21 ORY46980.1 - 1.1e-19 69.9 0.0 1.6e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF2486 PF10667.9 ORY46980.1 - 0.14 12.3 0.1 0.2 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) Mg_trans_NIPA PF05653.14 ORY46981.1 - 3e-68 230.1 21.3 3.8e-68 229.8 21.3 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORY46981.1 - 0.00041 20.5 0.9 0.00041 20.5 0.9 3.7 3 1 1 4 4 4 1 EamA-like transporter family DUF202 PF02656.15 ORY46981.1 - 1.5 9.3 5.2 34 5.0 0.6 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Mg_trans_NIPA PF05653.14 ORY46982.1 - 9.2e-31 107.0 16.4 1.1e-30 106.8 16.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA BCLP PF12304.8 ORY46982.1 - 2.3 7.8 8.8 0.12 11.9 1.4 2.3 1 1 0 2 2 2 0 Beta-casein like protein DUF2207 PF09972.9 ORY46984.1 - 0.071 11.9 0.1 0.08 11.7 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TUG-UBL1 PF11470.8 ORY46986.1 - 1.4e-18 66.9 0.6 3e-18 65.8 0.2 1.8 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 ORY46986.1 - 9.5e-10 38.6 0.0 9.7e-08 32.1 0.0 2.6 2 0 0 2 2 2 2 UBX domain zf-C2H2_aberr PF17017.5 ORY46990.1 - 8.6e-06 26.0 0.1 0.027 14.6 0.0 2.2 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 ORY46990.1 - 0.00036 20.8 2.3 0.04 14.4 0.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY46990.1 - 0.00068 20.3 7.9 0.035 15.0 0.2 2.7 3 0 0 3 3 3 2 C2H2-type zinc finger Nudix_N_2 PF14803.6 ORY46990.1 - 0.0012 18.8 0.0 0.0031 17.4 0.0 1.7 1 0 0 1 1 1 1 Nudix N-terminal zf-BED PF02892.15 ORY46990.1 - 0.0059 16.6 1.2 0.029 14.4 0.0 2.4 3 0 0 3 3 3 1 BED zinc finger zf-C2H2_jaz PF12171.8 ORY46990.1 - 0.019 15.2 0.3 0.19 12.0 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding ARS2 PF04959.13 ORY46990.1 - 0.058 13.8 0.8 0.16 12.4 0.1 2.0 2 0 0 2 2 2 0 Arsenite-resistance protein 2 zf-H2C2_2 PF13465.6 ORY46990.1 - 0.13 12.7 0.7 0.13 12.7 0.7 2.7 3 0 0 3 3 3 0 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 ORY46990.1 - 0.33 10.6 1.3 3.9 7.2 0.1 2.3 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain AT_hook PF02178.19 ORY46991.1 - 0.021 14.6 4.1 0.072 13.0 4.1 2.0 1 0 0 1 1 1 0 AT hook motif NDT80_PhoG PF05224.12 ORY46992.1 - 0.029 14.6 0.1 0.037 14.3 0.1 1.3 1 1 0 1 1 1 0 NDT80 / PhoG like DNA-binding family DUF5020 PF16412.5 ORY46992.1 - 0.071 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5020) p31comet PF06581.12 ORY46992.1 - 0.71 9.0 2.8 0.38 9.9 0.2 1.8 2 0 0 2 2 2 0 Mad1 and Cdc20-bound-Mad2 binding ABC_tran_CTD PF16326.5 ORY46992.1 - 1.9 8.8 5.9 0.96 9.7 0.2 2.3 1 1 2 3 3 3 0 ABC transporter C-terminal domain Aminotran_1_2 PF00155.21 ORY46995.1 - 4.7e-21 75.4 0.0 5.9e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 ORY46995.1 - 4.3e-08 32.4 0.0 5.8e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase p450 PF00067.22 ORY46997.1 - 2.8e-48 164.8 0.0 3.8e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Chitin_synth_1 PF01644.17 ORY46998.1 - 6.2e-69 231.1 0.0 9.2e-69 230.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 ORY46998.1 - 2.4e-29 102.4 2.0 6.2e-22 77.9 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 ORY46998.1 - 1.1e-14 54.2 0.2 1.5e-10 40.9 0.1 3.1 3 0 0 3 3 3 2 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 ORY46998.1 - 1.9e-08 34.4 4.9 3.4e-07 30.4 4.9 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY46998.1 - 0.084 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Inhibitor_I78 PF11720.8 ORY47000.1 - 0.00015 21.7 0.1 0.00032 20.7 0.1 1.6 1 1 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 ORY47000.1 - 0.00018 22.1 0.0 0.00058 20.5 0.0 1.7 2 0 0 2 2 2 1 Potato inhibitor I family 7tm_1 PF00001.21 ORY47002.1 - 6.9e-09 35.4 0.7 9e-09 35.0 0.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 ORY47002.1 - 1.8e-05 24.1 1.3 3.2e-05 23.3 1.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Frizzled PF01534.17 ORY47002.1 - 0.00021 20.4 2.1 0.00055 19.1 1.0 1.9 2 0 0 2 2 2 1 Frizzled/Smoothened family membrane region Dicty_CAR PF05462.11 ORY47002.1 - 0.00058 19.1 9.8 0.00064 18.9 5.2 2.0 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.8 ORY47002.1 - 0.0027 17.5 5.5 0.0027 17.5 5.5 2.0 2 1 1 3 3 3 1 G protein-coupled glucose receptor regulating Gpa2 GAT PF03127.14 ORY47003.1 - 0.069 13.5 2.5 2.7 8.4 0.1 3.0 2 1 1 3 3 3 0 GAT domain UCH PF00443.29 ORY47004.1 - 0.01 15.3 2.6 0.86 9.0 0.0 2.5 1 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase DUF429 PF04250.13 ORY47004.1 - 1.4 8.6 5.6 1.7 8.4 4.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF429) RNA_pol_Rpb5_C PF01191.19 ORY47004.1 - 2.4 8.1 6.3 2.9 7.8 0.1 3.8 4 0 0 4 4 4 0 RNA polymerase Rpb5, C-terminal domain YbjQ_1 PF01906.17 ORY47005.1 - 7.1e-27 94.1 0.2 8.2e-27 93.9 0.2 1.0 1 0 0 1 1 1 1 Putative heavy-metal-binding DUF4156 PF13698.6 ORY47005.1 - 0.0043 17.3 0.1 0.0067 16.7 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4156) zf-MYND PF01753.18 ORY47006.1 - 3.1e-08 33.5 11.3 7.1e-08 32.4 11.3 1.6 1 0 0 1 1 1 1 MYND finger AIPR PF10592.9 ORY47006.1 - 0.06 13.0 0.0 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 AIPR protein Ribosomal_L13 PF00572.18 ORY47007.1 - 7.5e-09 35.9 0.1 3e-07 30.7 0.0 2.7 2 1 0 2 2 2 1 Ribosomal protein L13 SH3_9 PF14604.6 ORY47009.1 - 0.00016 21.4 0.0 0.00029 20.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY47009.1 - 0.0028 17.2 0.0 0.0059 16.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain DUF3824 PF12868.7 ORY47009.1 - 0.006 17.3 2.2 0.006 17.3 2.2 2.8 2 1 1 3 3 3 1 Domain of unknwon function (DUF3824) ACC_epsilon PF13822.6 ORY47009.1 - 0.015 16.0 8.3 0.08 13.6 0.4 2.4 2 0 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit RskA PF10099.9 ORY47009.1 - 0.034 14.4 0.0 0.088 13.1 0.0 1.7 1 1 0 1 1 1 0 Anti-sigma-K factor rskA CRT10 PF08728.10 ORY47009.1 - 0.21 9.7 1.4 0.24 9.5 1.4 1.0 1 0 0 1 1 1 0 CRT10 Mito_fiss_reg PF05308.11 ORY47009.1 - 2.3 8.2 5.9 3.1 7.8 5.8 1.3 1 1 0 1 1 1 0 Mitochondrial fission regulator NDUF_B12 PF08122.12 ORY47009.1 - 3.4 7.8 5.6 4.6 7.4 1.5 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family DUF4598 PF15370.6 ORY47011.1 - 9.5e-21 74.4 2.0 9.5e-21 74.4 2.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) FAD-SLDH PF12318.8 ORY47011.1 - 0.2 11.7 0.6 0.27 11.3 0.6 1.1 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase ELMO_CED12 PF04727.13 ORY47012.1 - 2.1e-45 155.0 0.3 2.6e-45 154.7 0.3 1.1 1 0 0 1 1 1 1 ELMO/CED-12 family Med9 PF07544.13 ORY47013.1 - 0.078 13.1 0.4 0.078 13.1 0.4 3.4 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF465 PF04325.13 ORY47013.1 - 0.11 12.6 2.1 14 5.8 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF465) DUF4140 PF13600.6 ORY47013.1 - 0.77 10.2 6.1 3 8.3 2.7 2.8 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.9 ORY47013.1 - 0.96 8.5 8.1 0.63 9.1 6.1 1.7 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CC2-LZ PF16516.5 ORY47013.1 - 2 8.8 8.2 1.7 9.0 1.0 3.0 2 1 1 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator OAD_gamma PF04277.13 ORY47014.1 - 0.033 14.8 0.0 0.073 13.7 0.0 1.6 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF3377 PF11857.8 ORY47014.1 - 0.085 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DAGAT PF03982.13 ORY47015.1 - 1.6e-87 293.2 0.1 1.9e-87 293.0 0.1 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 ORY47015.1 - 0.0028 17.3 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF1218 PF06749.12 ORY47016.1 - 0.00016 22.1 4.4 0.0007 20.1 0.1 3.3 4 0 0 4 4 4 1 Protein of unknown function (DUF1218) MFS_1 PF07690.16 ORY47017.1 - 3.4e-12 45.9 32.9 1.5e-11 43.9 30.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 ORY47017.1 - 0.076 12.7 17.1 0.15 11.8 1.9 3.9 4 1 0 4 4 4 0 Ion channel regulatory protein UNC-93 DUF1218 PF06749.12 ORY47017.1 - 0.18 12.4 0.1 0.18 12.4 0.1 4.2 4 1 1 5 5 5 0 Protein of unknown function (DUF1218) GSHPx PF00255.19 ORY47018.1 - 2.9e-40 136.2 0.1 3.7e-40 135.8 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 ORY47018.1 - 0.0004 20.3 0.0 0.00062 19.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY47018.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.5 1 1 0 1 1 1 0 Redoxin DAGAT PF03982.13 ORY47019.1 - 1.6e-182 605.1 0.8 7.5e-92 307.4 0.1 2.0 2 0 0 2 2 2 2 Diacylglycerol acyltransferase Lipase_GDSL_2 PF13472.6 ORY47019.1 - 3.3e-05 24.3 0.0 0.037 14.4 0.0 2.2 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family DAGAT PF03982.13 ORY47020.1 - 2.3e-95 318.9 0.0 2.7e-95 318.7 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Peptidase_C48 PF02902.19 ORY47021.1 - 8.7e-24 84.6 0.6 1.2e-23 84.1 0.6 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DnaJ PF00226.31 ORY47022.1 - 1.1e-19 70.3 1.1 2.7e-19 69.1 1.1 1.7 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 ORY47022.1 - 2.1e-10 40.6 4.8 4.3e-10 39.6 4.8 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY47022.1 - 3e-08 33.8 3.2 5.8e-08 32.9 3.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 ORY47022.1 - 0.0013 19.0 0.1 0.0039 17.5 0.1 1.8 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.12 ORY47022.1 - 0.013 15.8 2.6 0.023 14.9 2.6 1.4 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) SAB PF04382.13 ORY47022.1 - 0.015 15.4 0.2 0.063 13.4 0.2 2.0 1 0 0 1 1 1 0 SAB domain zf-U1 PF06220.12 ORY47022.1 - 0.02 14.6 0.4 0.047 13.5 0.4 1.5 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2_4 PF13894.6 ORY47022.1 - 0.13 13.2 0.3 0.39 11.7 0.3 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger PIN_8 PF18476.1 ORY47022.1 - 2.4 8.0 12.2 0.34 10.7 7.5 2.0 2 1 1 3 3 3 0 PIN like domain Peptidase_C48 PF02902.19 ORY47023.1 - 3.2e-05 23.9 0.1 3.4e-05 23.8 0.1 1.0 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain TcpS PF17456.2 ORY47023.1 - 0.067 13.2 0.0 0.073 13.1 0.0 1.1 1 0 0 1 1 1 0 Toxin-coregulated pilus protein S Peptidase_C48 PF02902.19 ORY47024.1 - 1.1e-05 25.4 0.4 1.1e-05 25.4 0.4 1.7 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C48 PF02902.19 ORY47025.1 - 9.8e-11 41.9 0.3 1.9e-10 41.0 0.1 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain TLD PF07534.16 ORY47026.1 - 0.005 17.1 0.1 0.0097 16.1 0.1 1.5 1 0 0 1 1 1 1 TLD BTB PF00651.31 ORY47026.1 - 0.0075 16.5 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain PITH PF06201.13 ORY47027.1 - 6e-33 114.2 0.0 8.7e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 PITH domain Pirin PF02678.16 ORY47028.1 - 1.9e-30 105.0 0.6 3.1e-30 104.3 0.6 1.3 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 ORY47028.1 - 7.1e-17 61.7 0.0 3.9e-16 59.3 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Ribonuclease_T2 PF00445.18 ORY47029.1 - 1.5e-17 64.4 0.7 4.8e-17 62.8 0.0 1.9 2 1 0 2 2 2 1 Ribonuclease T2 family zf-UDP PF14569.6 ORY47030.1 - 0.028 14.5 0.4 0.06 13.5 0.4 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger GBP_C PF02841.14 ORY47030.1 - 9.1 5.6 21.5 0.19 11.1 11.3 2.1 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain zf-C2H2 PF00096.26 ORY47031.1 - 7e-26 89.2 29.5 3e-07 30.5 0.8 6.7 6 0 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY47031.1 - 1.6e-22 78.2 27.5 0.00017 22.2 0.5 6.5 6 0 0 6 6 6 6 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY47031.1 - 5.7e-19 67.6 34.9 2.4e-08 34.0 1.7 6.4 7 0 0 7 7 6 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY47031.1 - 1.2e-07 31.8 4.2 0.11 12.8 0.0 5.5 6 0 0 6 6 6 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ORY47031.1 - 3.9e-07 30.3 12.2 0.51 10.7 0.2 5.1 3 1 1 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 ORY47031.1 - 4.2e-06 26.6 14.5 0.0025 17.8 0.1 5.5 5 0 0 5 5 5 1 C2H2-type zinc finger zf-Di19 PF05605.12 ORY47031.1 - 1.1e-05 25.6 19.8 0.45 10.9 3.1 4.6 3 1 0 4 4 4 3 Drought induced 19 protein (Di19), zinc-binding GAGA PF09237.11 ORY47031.1 - 0.00022 21.0 8.1 0.0059 16.4 0.3 4.1 4 1 0 4 4 4 1 GAGA factor zf-H2C2_5 PF13909.6 ORY47031.1 - 0.00023 20.8 22.5 0.0023 17.6 0.5 5.6 5 0 0 5 5 5 2 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 ORY47031.1 - 0.0028 18.3 8.0 3.9 8.2 0.1 4.8 3 1 2 5 5 5 1 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 ORY47031.1 - 0.0032 17.8 9.9 0.5 10.8 0.1 4.8 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-Dof PF02701.15 ORY47031.1 - 0.0047 17.0 5.6 1.3 9.2 0.9 2.9 2 0 0 2 2 2 2 Dof domain, zinc finger zf-C2HE PF16278.5 ORY47031.1 - 0.0075 16.7 13.6 1.8 9.1 0.2 4.0 2 1 2 4 4 3 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 ORY47031.1 - 0.015 15.1 18.4 0.1 12.4 1.2 5.6 6 0 0 6 6 6 0 zinc-finger C2H2-type zf-LYAR PF08790.11 ORY47031.1 - 0.046 13.6 14.9 2.1 8.3 0.2 4.9 5 0 0 5 5 5 0 LYAR-type C2HC zinc finger TRAF6_Z2 PF18048.1 ORY47031.1 - 0.26 11.4 0.0 0.26 11.4 0.0 3.7 4 0 0 4 4 3 0 TNF receptor-associated factor 6 zinc finger 2 zf_UBZ PF18439.1 ORY47031.1 - 0.31 10.7 10.9 5.2 6.8 0.1 4.6 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger Lar_restr_allev PF14354.6 ORY47031.1 - 0.75 10.2 5.2 1.7 9.1 1.0 3.0 3 0 0 3 3 3 0 Restriction alleviation protein Lar zf_C2H2_6 PF18450.1 ORY47031.1 - 0.8 9.5 3.3 14 5.5 0.5 2.6 2 0 0 2 2 2 0 Zinc Finger domain zinc_ribbon_9 PF14369.6 ORY47031.1 - 1.2 9.5 14.6 0.84 10.0 0.1 4.5 5 0 0 5 5 4 0 zinc-ribbon zf-MYST PF17772.1 ORY47031.1 - 4.9 6.8 6.4 3.5 7.3 0.1 3.6 2 2 1 3 3 3 0 MYST family zinc finger domain zf_C2H2_ZHX PF18387.1 ORY47031.1 - 4.9 6.9 9.8 74 3.1 0.1 4.6 4 1 1 5 5 5 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF2225 PF09986.9 ORY47031.1 - 5.3 6.7 9.4 6.4 6.4 0.7 3.7 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) zinc_ribbon_15 PF17032.5 ORY47031.1 - 7.6 7.4 12.3 0.83 10.5 0.6 3.5 2 1 1 3 3 3 0 zinc-ribbon family Sprouty PF05210.13 ORY47031.1 - 8.1 6.9 8.0 50 4.4 1.2 3.2 3 0 0 3 3 3 0 Sprouty protein (Spry) zf-C2H2 PF00096.26 ORY47032.1 - 8.1e-23 79.6 24.2 6.2e-06 26.4 1.1 5.7 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY47032.1 - 2.9e-20 71.2 23.5 0.00082 20.0 0.7 5.6 5 0 0 5 5 5 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY47032.1 - 1.7e-16 59.8 26.8 5.3e-08 32.9 0.4 5.0 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY47032.1 - 3.8e-10 39.8 8.6 0.023 15.0 0.3 5.4 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY47032.1 - 1.3e-07 31.8 17.0 0.003 17.9 0.4 5.4 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2HE PF16278.5 ORY47032.1 - 2.4e-05 24.7 16.5 0.042 14.3 3.3 4.8 2 1 2 4 4 4 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 ORY47032.1 - 0.00045 20.5 14.0 0.68 10.3 0.6 4.0 2 1 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 ORY47032.1 - 0.0047 16.9 9.3 0.1 12.6 0.7 4.0 3 1 1 4 4 4 1 BED zinc finger zf-C2H2_6 PF13912.6 ORY47032.1 - 0.022 14.8 0.3 0.022 14.8 0.3 4.2 5 0 0 5 5 5 0 C2H2-type zinc finger C1_4 PF07975.12 ORY47032.1 - 0.031 14.5 13.5 0.96 9.7 1.8 3.5 3 0 0 3 3 3 0 TFIIH C1-like domain zf-H2C2_5 PF13909.6 ORY47032.1 - 0.061 13.1 19.4 0.41 10.5 0.5 4.7 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zinc_ribbon_15 PF17032.5 ORY47032.1 - 0.22 12.3 9.2 1.9 9.3 0.7 3.4 2 1 1 3 3 3 0 zinc-ribbon family Zn_ribbon_SprT PF17283.2 ORY47032.1 - 0.31 11.0 14.9 1.4 8.9 0.0 4.7 4 1 1 5 5 5 0 SprT-like zinc ribbon domain zf-C2H2_11 PF16622.5 ORY47032.1 - 0.37 10.6 14.1 2 8.2 0.6 5.0 5 0 0 5 5 5 0 zinc-finger C2H2-type zf-C2H2_9 PF16293.5 ORY47032.1 - 1 9.3 3.8 15 5.5 0.1 3.1 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) GAGA PF09237.11 ORY47032.1 - 1.2 9.0 12.0 1.9 8.3 0.2 3.1 3 0 0 3 3 2 0 GAGA factor zf-MYST PF17772.1 ORY47032.1 - 1.5 8.5 6.7 3.3 7.4 0.1 3.4 2 2 1 3 3 3 0 MYST family zinc finger domain zf-UBP PF02148.19 ORY47032.1 - 2 8.8 0.0 2 8.8 0.0 3.1 2 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2_3rep PF18868.1 ORY47032.1 - 3.4 8.4 12.9 12 6.6 0.6 4.5 2 2 2 5 5 5 0 Zinc finger C2H2-type, 3 repeats zf_UBZ PF18439.1 ORY47032.1 - 7.1 6.3 10.8 24 4.6 0.0 4.4 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger DUF3446 PF11928.8 ORY47033.1 - 2.8 8.3 10.7 5.7 7.3 10.7 1.6 1 1 0 1 1 1 0 Early growth response N-terminal domain HECT PF00632.25 ORY47034.1 - 3.2e-85 286.3 0.0 3.6e-85 286.2 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) LRR_4 PF12799.7 ORY47035.1 - 1e-15 57.6 6.4 5.4e-07 29.8 0.3 3.8 2 1 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY47035.1 - 5.9e-07 29.2 8.6 0.00025 20.8 0.5 3.5 1 1 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 ORY47035.1 - 1.1e-06 28.3 0.1 1.2e-05 24.9 0.1 2.4 1 1 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 ORY47035.1 - 0.011 16.2 3.5 45 5.1 0.0 5.2 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 ORY47035.1 - 0.76 10.0 8.0 11 6.3 0.1 4.3 5 0 0 5 5 5 0 Leucine Rich repeat Gp_dh_C PF02800.20 ORY47037.1 - 5.8e-65 217.7 0.1 9.2e-65 217.1 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 ORY47037.1 - 5.7e-39 132.5 0.0 1.3e-38 131.4 0.0 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Mob1_phocein PF03637.17 ORY47037.1 - 7.9e-28 97.6 0.4 1.5e-27 96.7 0.4 1.4 1 0 0 1 1 1 1 Mob1/phocein family DapB_N PF01113.20 ORY47037.1 - 0.1 12.7 0.0 0.36 10.9 0.0 1.9 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus BTB PF00651.31 ORY47038.1 - 2.1e-11 44.0 0.0 4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain TLD PF07534.16 ORY47038.1 - 4.9e-06 26.8 0.1 9.8e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 TLD Rep_1B PF17873.1 ORY47038.1 - 0.18 11.7 0.4 5.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Replicase polyprotein 1ab CLP_protease PF00574.23 ORY47039.1 - 5.5e-78 261.0 0.1 6.4e-78 260.8 0.1 1.0 1 0 0 1 1 1 1 Clp protease Myosin_head PF00063.21 ORY47040.1 - 5.9e-263 874.1 0.6 1.1e-262 873.2 0.6 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 ORY47040.1 - 1.4e-29 102.4 1.4 1.4e-29 102.4 1.4 2.7 3 0 0 3 3 1 1 DIL domain IQ PF00612.27 ORY47040.1 - 2.6e-14 51.6 35.5 1.5e-06 27.5 0.6 6.2 6 0 0 6 6 6 4 IQ calmodulin-binding motif Flg_hook PF02120.16 ORY47040.1 - 0.014 15.2 1.9 17 5.4 0.0 3.9 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK AAA_22 PF13401.6 ORY47040.1 - 0.017 15.4 0.0 0.065 13.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain Myosin_N PF02736.19 ORY47040.1 - 0.018 14.9 0.5 0.16 11.9 0.1 2.5 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain ATP_bind_2 PF03668.15 ORY47040.1 - 0.058 12.7 0.0 2.7 7.2 0.0 2.6 2 0 0 2 2 2 0 P-loop ATPase protein family HAP1_N PF04849.13 ORY47040.1 - 0.084 12.1 17.1 0.19 10.9 17.1 1.5 1 0 0 1 1 1 0 HAP1 N-terminal conserved region AAA_16 PF13191.6 ORY47040.1 - 0.11 12.8 3.3 0.22 11.9 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain Csm1_N PF18504.1 ORY47040.1 - 0.4 11.1 18.3 0.75 10.2 0.9 3.8 3 0 0 3 3 3 0 Csm1 N-terminal domain DUF1664 PF07889.12 ORY47040.1 - 0.66 10.0 10.0 5.5 7.1 3.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 ORY47040.1 - 3.1 8.3 17.4 0.18 12.3 2.8 3.4 3 0 0 3 3 3 0 Protein of unknown function DUF16 Cep57_CLD_2 PF14197.6 ORY47040.1 - 3.3 7.9 11.5 0.9 9.7 5.7 2.9 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF4407 PF14362.6 ORY47040.1 - 4.4 6.6 19.1 1.1 8.6 14.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.8 ORY47040.1 - 6.7 6.8 33.4 0.21 11.6 8.1 3.6 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 ORY47040.1 - 7.1 6.7 21.6 2.8e+02 1.5 21.6 2.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CLZ PF16526.5 ORY47040.1 - 7.7 7.0 9.1 0.85 10.0 0.6 3.3 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SlyX PF04102.12 ORY47040.1 - 8.7 7.0 13.5 6.3 7.5 0.3 4.4 3 1 2 5 5 4 0 SlyX NAD_binding_10 PF13460.6 ORY47041.1 - 9.9e-20 71.2 1.1 1.7e-19 70.4 1.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 ORY47041.1 - 3.1e-18 66.2 1.5 4.3e-18 65.7 1.5 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 ORY47041.1 - 1.4e-05 24.4 0.3 0.007 15.5 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain Epimerase PF01370.21 ORY47041.1 - 2.2e-05 24.1 1.2 0.00011 21.8 0.3 2.4 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ORY47041.1 - 0.00059 19.1 0.1 0.0026 17.0 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 ORY47041.1 - 0.0036 16.4 0.0 0.007 15.4 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 ORY47041.1 - 0.0046 17.1 0.5 0.013 15.6 0.1 2.0 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus GDP_Man_Dehyd PF16363.5 ORY47041.1 - 0.0053 16.2 0.6 0.022 14.2 0.0 2.2 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 ORY47041.1 - 0.0098 15.4 0.2 0.044 13.2 0.1 2.1 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 ORY47041.1 - 0.047 13.6 1.8 0.32 10.9 1.8 2.4 1 1 0 1 1 1 0 KR domain PAC2 PF09754.9 ORY47041.1 - 0.049 13.6 0.0 0.077 13.0 0.0 1.4 1 1 0 1 1 1 0 PAC2 family Ank_5 PF13857.6 ORY47042.1 - 1.1e-15 57.4 0.1 3.8e-06 27.1 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY47042.1 - 5.7e-14 52.5 0.1 0.001 19.6 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY47042.1 - 4.4e-10 39.9 0.8 0.35 11.5 0.0 5.3 3 2 2 5 5 5 5 Ankyrin repeats (many copies) zf-C3HC4 PF00097.25 ORY47042.1 - 8.6e-10 38.3 8.6 1.8e-09 37.3 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY47042.1 - 2.3e-09 37.1 5.5 5.2e-09 36.0 5.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Ank_3 PF13606.6 ORY47042.1 - 2.3e-08 33.6 2.9 0.45 11.2 0.0 7.8 8 0 0 8 8 7 1 Ankyrin repeat zf-C3HC4_3 PF13920.6 ORY47042.1 - 3.1e-08 33.3 6.8 5.8e-08 32.5 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY47042.1 - 3.9e-08 33.3 9.2 8.3e-08 32.3 9.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 ORY47042.1 - 6.2e-08 32.8 7.8 1.5e-07 31.6 7.8 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY47042.1 - 1.3e-07 31.3 8.8 2.8e-07 30.3 8.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY47042.1 - 1.6e-07 31.2 6.7 3.3e-07 30.2 6.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY47042.1 - 0.00025 20.8 7.8 0.00093 19.0 7.9 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 ORY47042.1 - 0.0037 17.3 2.2 0.065 13.3 2.2 2.7 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Ank PF00023.30 ORY47042.1 - 0.0045 17.4 0.5 16 6.2 0.0 5.1 5 0 0 5 5 5 0 Ankyrin repeat zf-rbx1 PF12678.7 ORY47042.1 - 0.0093 16.2 4.3 0.028 14.7 4.3 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 ORY47042.1 - 0.069 12.9 5.6 0.2 11.5 5.6 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 ORY47042.1 - 0.24 11.2 6.1 0.66 9.8 6.1 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 ORY47042.1 - 0.56 10.1 3.6 1.6 8.6 3.6 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DZR PF12773.7 ORY47042.1 - 0.87 9.7 5.0 2.6 8.2 5.0 1.8 1 0 0 1 1 1 0 Double zinc ribbon Thioredoxin_16 PF18569.1 ORY47043.1 - 0.21 11.7 0.1 9.9 6.4 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like domain HRG PF16954.5 ORY47044.1 - 0.78 10.2 7.1 0.45 10.9 0.9 3.5 3 1 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene OB_NTP_bind PF07717.16 ORY47047.1 - 3.9e-21 75.2 0.0 1.3e-20 73.5 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 ORY47047.1 - 3e-06 27.6 0.2 1e-05 25.9 0.2 1.8 1 1 1 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY47047.1 - 0.027 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase HA2 PF04408.23 ORY47047.1 - 0.49 10.7 2.9 12 6.3 0.3 2.5 1 1 1 2 2 2 0 Helicase associated domain (HA2) CASP_C PF08172.12 ORY47048.1 - 0.0038 16.6 2.9 0.0038 16.6 2.9 1.4 1 1 0 1 1 1 1 CASP C terminal SlyX PF04102.12 ORY47048.1 - 0.0042 17.7 6.0 0.008 16.8 1.3 2.4 1 1 1 2 2 2 1 SlyX Apt1 PF10351.9 ORY47048.1 - 0.071 12.0 6.5 0.079 11.8 6.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain TMEM192 PF14802.6 ORY47048.1 - 0.12 11.4 1.3 0.14 11.2 1.3 1.2 1 0 0 1 1 1 0 TMEM192 family EMC3_TMCO1 PF01956.16 ORY47048.1 - 2.7 7.7 4.0 1.2 8.8 2.0 1.5 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF3842 PF12953.7 ORY47051.1 - 0.043 14.2 0.0 0.078 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) Ipi1_N PF12333.8 ORY47052.1 - 6.5e-14 52.4 0.4 6.1e-13 49.2 0.1 2.9 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation LRR_9 PF14580.6 ORY47053.1 - 2.1e-16 59.9 3.3 1.9e-15 56.8 3.4 2.1 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 ORY47053.1 - 1.2e-15 57.4 14.0 4.1e-06 27.0 3.4 4.9 3 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY47053.1 - 2.8e-11 43.0 8.6 4.7e-06 26.3 2.0 4.1 2 2 1 3 3 3 3 Leucine rich repeat baeRF_family10 PF18854.1 ORY47053.1 - 0.0074 16.5 2.5 0.0074 16.5 2.5 2.1 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 10 LRR_6 PF13516.6 ORY47053.1 - 0.033 14.2 3.5 0.12 12.5 0.0 3.5 5 0 0 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.33 ORY47053.1 - 3.7 8.4 7.8 2.8e+02 2.8 0.0 5.0 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_9 PF14580.6 ORY47054.1 - 3.5e-21 75.5 19.0 7.8e-12 45.0 3.8 3.3 2 1 1 3 3 3 3 Leucine-rich repeat LRR_4 PF12799.7 ORY47054.1 - 1.2e-15 57.4 36.6 5.7e-08 32.9 0.7 6.4 3 1 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY47054.1 - 1.5e-13 50.3 21.7 1.6e-07 31.0 5.3 5.3 4 1 3 7 7 7 5 Leucine rich repeat LRR_6 PF13516.6 ORY47054.1 - 0.045 13.8 14.3 14 6.1 0.1 6.2 5 1 1 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 ORY47054.1 - 7.6 7.5 18.5 21 6.2 1.8 6.5 5 2 0 5 5 5 0 Leucine Rich Repeat Metallophos PF00149.28 ORY47058.1 - 1.7e-13 51.6 1.3 2.8e-13 50.8 1.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PGA_cap PF09587.10 ORY47058.1 - 0.0054 16.2 0.1 0.0085 15.6 0.1 1.3 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap DEAD PF00270.29 ORY47060.1 - 1.4e-36 125.9 0.0 7.1e-20 71.5 0.0 2.3 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY47060.1 - 1.5e-22 80.0 0.0 5.6e-22 78.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 ORY47060.1 - 8.4e-19 67.6 0.1 1.9e-18 66.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 ORY47060.1 - 1.9e-06 28.0 0.0 5.3e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4611 PF15387.6 ORY47060.1 - 0.0096 16.1 0.8 0.0096 16.1 0.8 4.0 2 1 2 4 4 4 1 Domain of unknown function (DUF4611) DUF3176 PF11374.8 ORY47060.1 - 0.066 13.4 0.2 0.13 12.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) AAA_22 PF13401.6 ORY47060.1 - 0.074 13.3 0.0 1.1 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain JHD PF17811.1 ORY47061.1 - 2.9e-11 43.8 0.3 6.6e-11 42.7 0.3 1.6 1 0 0 1 1 1 1 Jumonji helical domain PfUIS3 PF11567.8 ORY47061.1 - 0.02 15.3 0.5 0.052 13.9 0.1 1.9 2 0 0 2 2 2 0 Plasmodium falciparum UIS3 membrane protein PHD PF00628.29 ORY47062.1 - 3.2e-11 42.9 8.5 3.6e-11 42.8 8.5 1.1 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 ORY47062.1 - 0.0011 18.8 9.4 0.0053 16.6 3.6 2.1 1 1 1 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 ORY47062.1 - 0.011 15.8 1.9 0.017 15.2 1.9 1.3 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 ORY47062.1 - 0.036 14.2 4.2 0.057 13.5 4.2 1.4 1 1 0 1 1 1 0 KIAA1045 RING finger zf-RING_9 PF13901.6 ORY47062.1 - 0.041 13.9 4.4 0.05 13.6 4.4 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Laminin_EGF PF00053.24 ORY47062.1 - 1.1 9.5 8.0 0.38 10.9 2.6 2.1 1 1 1 2 2 2 0 Laminin EGF domain Terminase_GpA PF05876.12 ORY47062.1 - 2.5 6.5 4.1 2.8 6.4 4.1 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) FAD_binding_3 PF01494.19 ORY47065.1 - 2.9e-22 79.4 2.0 2e-20 73.3 2.0 2.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY47065.1 - 3.8e-08 32.9 0.1 0.0066 15.7 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY47065.1 - 7.4e-05 22.9 0.1 0.00016 21.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORY47065.1 - 0.0002 20.7 0.0 0.01 15.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY47065.1 - 0.00038 20.2 0.3 0.036 13.7 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 ORY47065.1 - 0.0056 16.1 0.0 0.068 12.5 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 ORY47065.1 - 0.0064 15.6 0.2 0.049 12.7 0.2 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein 3HCDH_N PF02737.18 ORY47065.1 - 0.0078 16.1 0.0 0.089 12.7 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 ORY47065.1 - 0.0079 15.3 0.3 0.024 13.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.22 ORY47065.1 - 0.0085 15.2 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 ORY47065.1 - 0.013 14.3 0.2 0.28 9.8 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.14 ORY47065.1 - 0.053 13.1 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.6 ORY47065.1 - 0.053 13.5 0.3 1.2 9.1 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FMO-like PF00743.19 ORY47065.1 - 0.068 11.6 0.0 0.13 10.6 0.0 1.4 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 ORY47066.1 - 1.6e-18 66.9 0.0 6.7e-14 51.8 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 ORY47066.1 - 0.0035 17.3 0.0 0.73 9.8 0.0 2.8 2 1 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 ORY47066.1 - 0.01 15.1 0.0 0.076 12.2 0.0 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 ORY47066.1 - 0.042 13.9 0.0 0.45 10.6 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase StbA PF06406.11 ORY47066.1 - 0.063 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 StbA protein BTB PF00651.31 ORY47067.1 - 0.00078 19.7 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 ORY47068.1 - 2.8e-05 24.3 0.0 7.6e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain TLD PF07534.16 ORY47068.1 - 6e-05 23.3 0.2 0.00021 21.5 0.1 2.0 2 0 0 2 2 2 1 TLD Methyltransf_4 PF02390.17 ORY47069.1 - 1.1e-55 187.7 0.0 1.6e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 ORY47069.1 - 0.0014 18.2 0.1 0.12 11.9 0.1 2.6 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ORY47069.1 - 0.0027 18.4 0.0 0.0071 17.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY47069.1 - 0.0097 15.8 0.0 0.031 14.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY47069.1 - 0.031 14.9 0.0 0.18 12.5 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 ORY47069.1 - 0.042 14.6 0.0 0.12 13.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Phosphoesterase PF04185.14 ORY47070.1 - 7.3e-26 91.2 0.1 2.8e-22 79.4 0.1 2.7 2 1 1 3 3 3 2 Phosphoesterase family Zap1_zf2 PF18217.1 ORY47070.1 - 0.086 12.8 0.8 0.21 11.6 0.8 1.6 1 0 0 1 1 1 0 Zap1 zinc finger 2 KDZ PF18758.1 ORY47071.1 - 1.7e-26 93.2 0.0 3.1e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 ORY47071.1 - 1.4e-05 25.2 0.5 3.5e-05 23.9 0.1 1.9 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases DUF948 PF06103.11 ORY47071.1 - 0.055 13.7 0.1 1.9 8.8 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CxC2 PF18803.1 ORY47071.1 - 0.077 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases TBCA PF02970.16 ORY47071.1 - 0.2 12.0 0.7 1.5 9.2 0.0 2.4 2 1 0 2 2 2 0 Tubulin binding cofactor A CdvA PF18822.1 ORY47071.1 - 0.23 11.3 2.4 0.45 10.4 0.8 2.2 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF3523 PF12037.8 ORY47073.1 - 0.031 13.6 5.9 0.32 10.3 3.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3523) Rsc14 PF08586.10 ORY47073.1 - 0.47 11.3 2.3 1.6 9.5 1.0 2.3 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit adh_short PF00106.25 ORY47074.1 - 5.7e-27 94.5 0.0 6.9e-27 94.2 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY47074.1 - 1.7e-23 83.4 0.0 3.1e-23 82.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY47074.1 - 2.8e-07 30.6 0.0 4.7e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 ORY47074.1 - 0.0003 20.7 0.0 0.0007 19.5 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 ORY47074.1 - 0.0011 18.5 0.0 0.0057 16.2 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family F420_oxidored PF03807.17 ORY47074.1 - 0.003 18.1 0.1 0.31 11.7 0.1 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.10 ORY47074.1 - 0.0045 16.4 0.0 0.0087 15.5 0.0 1.3 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 ORY47075.1 - 4.9e-26 91.4 0.0 6e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY47075.1 - 1.6e-22 80.2 0.0 2.4e-22 79.7 0.0 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY47075.1 - 7.9e-05 22.6 0.0 0.00013 21.9 0.0 1.3 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 ORY47075.1 - 0.00063 19.2 0.0 0.0013 18.1 0.0 1.4 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 ORY47075.1 - 0.0041 16.7 0.1 0.0086 15.6 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 ORY47075.1 - 0.0098 15.8 0.0 0.027 14.4 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding F420_oxidored PF03807.17 ORY47075.1 - 0.14 12.8 0.1 7.8 7.2 0.1 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Fungal_trans PF04082.18 ORY47076.1 - 0.00037 19.6 0.6 0.00077 18.6 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY47076.1 - 0.013 15.6 5.7 0.026 14.6 5.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PPTA PF01239.22 ORY47078.1 - 3.7e-41 137.7 10.2 1.3e-09 37.5 0.0 5.2 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Lip_A_acyltrans PF03279.13 ORY47078.1 - 0.0069 15.6 0.7 0.026 13.7 0.2 1.9 2 0 0 2 2 2 1 Bacterial lipid A biosynthesis acyltransferase TPR_17 PF13431.6 ORY47078.1 - 0.048 14.1 0.2 7.1 7.3 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 ORY47078.1 - 0.097 12.8 4.6 13 6.0 0.1 3.9 2 1 2 4 4 4 0 Tetratricopeptide repeat DUF2946 PF11162.8 ORY47079.1 - 0.063 13.9 0.2 1.9 9.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) DUF3561 PF12084.8 ORY47079.1 - 0.27 11.3 2.6 0.64 10.1 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3561) Ank_2 PF12796.7 ORY47080.1 - 2.1e-32 111.6 4.6 2.1e-17 63.4 1.1 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY47080.1 - 2.5e-29 101.3 2.0 3.1e-09 37.2 0.0 4.1 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY47080.1 - 1.2e-26 91.9 9.7 9.5e-05 22.7 0.1 5.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 ORY47080.1 - 2.5e-25 88.2 1.8 1.8e-10 40.8 0.1 4.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY47080.1 - 1.2e-24 83.6 2.1 0.0018 18.6 0.0 5.4 6 0 0 6 6 6 5 Ankyrin repeat VWA_3_C PF18571.1 ORY47080.1 - 0.011 15.6 8.4 1 9.3 0.1 4.0 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain zf_C2H2_ZHX PF18387.1 ORY47081.1 - 0.015 14.9 6.2 0.8 9.4 0.8 2.5 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain OrsD PF12013.8 ORY47081.1 - 0.044 14.2 6.2 0.23 11.9 1.4 2.9 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2 PF00096.26 ORY47081.1 - 0.51 10.9 11.0 1.6 9.4 0.1 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type BUD22 PF09073.10 ORY47082.1 - 1.9 7.8 11.8 2.3 7.5 11.8 1.1 1 0 0 1 1 1 0 BUD22 ArsA_ATPase PF02374.15 ORY47202.1 - 1.2e-81 274.2 1.8 2.9e-81 273.0 1.8 1.5 1 1 0 1 1 1 1 Anion-transporting ATPase Pyr_redox_2 PF07992.14 ORY47203.1 - 3e-51 174.4 0.0 3.6e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY47203.1 - 9.2e-12 45.4 0.0 5e-11 43.0 0.1 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY47203.1 - 0.00033 20.0 0.0 0.22 10.7 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY47203.1 - 0.0073 15.9 0.1 0.77 9.3 0.0 2.8 2 1 1 3 3 3 1 FAD dependent oxidoreductase TrkA_TMD PF18613.1 ORY47203.1 - 0.088 12.3 1.1 0.21 11.0 1.1 1.6 1 0 0 1 1 1 0 Tyrosine kinase receptor A trans-membrane domain NAD_binding_9 PF13454.6 ORY47203.1 - 0.1 12.5 0.0 3.5 7.6 0.0 2.8 2 1 1 3 3 3 0 FAD-NAD(P)-binding Peptidase_C2 PF00648.21 ORY47204.1 - 8.8e-09 34.8 0.0 4.2e-08 32.6 0.0 2.0 2 0 0 2 2 2 1 Calpain family cysteine protease Homeodomain PF00046.29 ORY47205.1 - 4.7e-15 55.2 3.0 1.1e-14 54.0 3.0 1.6 1 0 0 1 1 1 1 Homeodomain YdaS_antitoxin PF15943.5 ORY47205.1 - 0.042 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT RhoGAP PF00620.27 ORY47208.1 - 1.5e-49 167.7 0.0 2.2e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 ORY47208.1 - 2.8e-06 27.8 0.0 8e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 PH domain WW PF00397.26 ORY47208.1 - 4e-06 26.8 3.8 4e-06 26.8 3.8 1.9 2 0 0 2 2 2 1 WW domain PH_9 PF15410.6 ORY47208.1 - 7.4e-05 23.1 0.0 0.00015 22.1 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF1708 PF08101.11 ORY47208.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) p450 PF00067.22 ORY47209.1 - 2.1e-74 251.0 0.1 2.4e-74 250.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C3HC4_2 PF13923.6 ORY47210.1 - 7e-10 38.6 8.1 7e-10 38.6 8.1 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY47210.1 - 3.9e-09 36.2 7.0 3.9e-09 36.2 7.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.27 ORY47210.1 - 4.6e-09 35.8 1.8 8.8e-09 34.9 1.8 1.5 1 0 0 1 1 1 1 SAP domain zf-C3HC4 PF00097.25 ORY47210.1 - 8.4e-08 32.0 7.1 8.4e-08 32.0 7.1 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY47210.1 - 1.2e-07 31.9 9.1 1.2e-07 31.9 9.1 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 ORY47210.1 - 1.7e-06 27.9 7.5 1.7e-06 27.9 7.5 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY47210.1 - 7.6e-06 25.9 5.5 7.6e-06 25.9 5.5 2.5 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 ORY47210.1 - 0.00011 22.0 14.3 0.00013 21.8 8.0 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 ORY47210.1 - 0.0006 19.9 7.1 0.0006 19.9 7.1 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 ORY47210.1 - 0.00093 19.4 4.4 0.00093 19.4 4.4 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 ORY47210.1 - 0.0018 18.1 5.8 0.0018 18.1 5.8 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein RNF220 PF15926.5 ORY47210.1 - 0.0026 17.4 3.1 0.17 11.5 0.4 2.6 2 0 0 2 2 2 2 E3 ubiquitin-protein ligase RNF220 zf-RING_10 PF16685.5 ORY47210.1 - 4.4 7.5 15.4 0.23 11.6 8.2 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 ORY47210.1 - 7.3 6.5 14.0 0.42 10.4 6.3 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain LRR_8 PF13855.6 ORY47211.1 - 1e-25 89.2 32.3 1.4e-08 34.3 3.0 4.3 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY47211.1 - 7.2e-23 80.3 26.9 6.5e-06 26.4 0.7 6.2 4 2 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY47211.1 - 1.7e-10 40.0 27.9 1.7 9.5 0.0 9.2 10 0 0 10 10 10 5 Leucine Rich Repeat LRR_2 PF07723.13 ORY47211.1 - 0.0047 17.5 0.7 32 5.4 0.1 5.1 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_9 PF14580.6 ORY47211.1 - 0.61 9.6 4.4 4 6.9 0.3 2.6 1 1 1 3 3 3 0 Leucine-rich repeat Resolvase PF00239.21 ORY47212.1 - 4.5e-13 49.6 0.0 1.3e-12 48.1 0.0 1.7 1 0 0 1 1 1 1 Resolvase, N terminal domain Adaptin_binding PF10199.9 ORY47212.1 - 1.3e-08 35.5 7.0 4.4e-08 33.8 7.0 1.9 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 LRR_8 PF13855.6 ORY47213.1 - 1e-23 82.8 10.4 4.9e-07 29.4 0.3 5.7 5 2 1 7 7 7 4 Leucine rich repeat LRR_4 PF12799.7 ORY47213.1 - 5.9e-22 77.4 1.2 0.00031 21.1 0.0 5.5 5 0 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY47213.1 - 1.5e-13 49.2 12.4 0.58 10.9 0.1 9.3 9 1 0 9 9 9 5 Leucine Rich Repeat F-box PF00646.33 ORY47213.1 - 4e-06 26.6 0.2 1.3e-05 25.0 0.2 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY47213.1 - 5.6e-06 26.2 0.6 1.4e-05 24.9 0.6 1.7 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 ORY47213.1 - 0.00018 21.3 16.1 6.7 7.0 0.0 8.1 9 0 0 9 9 9 1 Leucine Rich repeat HCV_core PF01542.18 ORY47213.1 - 0.12 12.8 0.1 0.31 11.5 0.1 1.8 1 0 0 1 1 1 0 Hepatitis C virus core protein SAP PF02037.27 ORY47214.1 - 2.9e-05 23.7 0.0 5.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 SAP domain AT_hook PF02178.19 ORY47214.1 - 1 9.5 31.4 0.47 10.5 2.5 3.8 4 0 0 4 4 4 0 AT hook motif LRR_8 PF13855.6 ORY47215.1 - 6.5e-44 147.5 42.9 2.5e-09 36.8 3.1 9.6 6 4 2 9 9 9 8 Leucine rich repeat LRR_4 PF12799.7 ORY47215.1 - 3.3e-39 132.2 40.7 4.8e-07 30.0 2.4 11.3 6 2 1 11 11 11 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY47215.1 - 6.4e-18 62.5 54.4 1.9 9.3 0.0 18.3 18 1 1 19 19 19 8 Leucine Rich Repeat F-box PF00646.33 ORY47215.1 - 1.9e-11 43.5 0.0 1.2e-05 25.1 0.0 3.0 2 0 0 2 2 2 2 F-box domain LRR_6 PF13516.6 ORY47215.1 - 3.1e-09 36.1 48.6 11 6.3 0.0 16.7 18 0 0 18 18 18 2 Leucine Rich repeat F-box-like PF12937.7 ORY47215.1 - 2e-05 24.3 0.9 0.0059 16.5 0.1 2.9 2 0 0 2 2 2 2 F-box-like LRR_9 PF14580.6 ORY47215.1 - 0.00057 19.4 7.3 0.38 10.2 0.2 4.3 2 2 2 4 4 4 2 Leucine-rich repeat p450 PF00067.22 ORY47216.1 - 1.8e-61 208.4 0.1 2.6e-61 207.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 Bin3 PF06859.12 ORY47217.1 - 1.4e-23 83.6 0.0 2e-23 83.1 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_31 PF13847.6 ORY47217.1 - 9.9e-11 41.7 0.0 9.3e-06 25.5 0.1 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 ORY47217.1 - 1.4e-09 38.5 0.1 2.8e-05 24.7 0.1 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 ORY47217.1 - 3e-07 31.0 0.0 0.024 15.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 ORY47217.1 - 5.4e-06 26.3 0.0 6.6e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY47217.1 - 9.7e-06 26.2 0.0 0.00012 22.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY47217.1 - 0.0029 17.2 0.1 0.0088 15.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 ORY47217.1 - 0.0042 16.5 0.1 0.0061 16.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GP79 PF17463.2 ORY47217.1 - 0.0057 16.6 1.5 0.52 10.4 0.4 3.1 2 1 1 3 3 3 1 Gene product 79 Methyltransf_9 PF08003.11 ORY47217.1 - 0.0062 15.5 0.0 0.058 12.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) CMAS PF02353.20 ORY47217.1 - 0.0065 15.8 0.0 2.7 7.2 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase PCMT PF01135.19 ORY47217.1 - 0.052 13.3 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_PK PF05891.12 ORY47217.1 - 0.12 11.9 0.0 0.47 9.9 0.0 1.8 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase Ubie_methyltran PF01209.18 ORY47217.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TatD_DNase PF01026.21 ORY47218.1 - 4.8e-31 108.0 0.0 6.1e-31 107.7 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase CAMSAP_CKK PF08683.11 ORY47220.1 - 4e-21 75.4 0.0 6e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Microtubule-binding calmodulin-regulated spectrin-associated ABC_tran PF00005.27 ORY47221.1 - 9.8e-34 116.8 0.0 2.1e-18 67.1 0.0 3.6 2 1 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 ORY47221.1 - 1e-21 76.8 3.0 1e-21 76.8 3.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 ORY47221.1 - 7.7e-10 39.1 6.2 0.00046 20.1 0.1 3.8 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY47221.1 - 5e-06 26.1 0.0 0.079 12.4 0.0 3.1 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 ORY47221.1 - 0.0015 18.8 0.0 0.004 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORY47221.1 - 0.0021 17.7 0.0 0.22 11.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 ORY47221.1 - 0.0078 16.6 0.0 0.036 14.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORY47221.1 - 0.0098 16.3 0.4 0.23 11.9 0.0 2.7 3 0 0 3 3 2 1 RNA helicase AAA_18 PF13238.6 ORY47221.1 - 0.018 15.6 0.0 0.23 12.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 ORY47221.1 - 0.024 14.7 0.0 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ORY47221.1 - 0.027 15.0 8.6 0.14 12.6 0.0 3.4 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.6 ORY47221.1 - 0.049 14.0 0.0 0.28 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 ORY47221.1 - 0.055 13.4 0.0 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 ORY47221.1 - 0.058 13.3 0.3 1.2 9.0 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase AAA_33 PF13671.6 ORY47221.1 - 0.072 13.2 0.0 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 ORY47221.1 - 0.092 12.7 0.0 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 NACHT domain ABC_tran_CTD PF16326.5 ORY47221.1 - 0.25 11.6 9.3 0.045 14.0 2.9 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain TipAS PF07739.13 ORY47221.1 - 0.28 11.7 4.1 11 6.6 0.1 2.8 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain Pkinase PF00069.25 ORY47222.1 - 1.5e-13 50.7 0.0 3.8e-13 49.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY47222.1 - 6.1e-05 22.4 0.2 0.0023 17.3 0.0 2.9 3 1 0 3 3 3 1 Protein tyrosine kinase Thioredoxin_14 PF18402.1 ORY47222.1 - 0.03 14.3 0.2 0.03 14.3 0.2 1.6 2 0 0 2 2 2 0 Thioredoxin-like domain EPL1 PF10513.9 ORY47222.1 - 0.25 11.7 5.3 5.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like Pkinase PF00069.25 ORY47223.1 - 1.4e-14 54.1 0.0 3e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY47223.1 - 3.5e-05 23.2 0.0 0.00096 18.5 0.0 2.8 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 ORY47224.1 - 5.5e-20 71.8 0.0 8.5e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY47224.1 - 2.6e-08 33.5 0.0 4.4e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY47224.1 - 3.8e-06 25.9 0.1 6.6e-06 25.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase CDK2AP PF09806.9 ORY47224.1 - 0.32 11.0 9.3 8.3 6.4 5.4 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein adh_short PF00106.25 ORY47225.1 - 1.2e-21 77.1 2.0 7.9e-14 51.6 0.1 3.1 2 1 1 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 ORY47225.1 - 3.9e-13 49.5 0.0 2.6e-11 43.5 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2373 PF10180.9 ORY47227.1 - 6e-08 32.4 4.8 1.2e-07 31.5 4.8 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) TSGP1 PF07771.11 ORY47227.1 - 4.9 7.3 9.2 7.7 6.7 9.2 1.3 1 0 0 1 1 1 0 Tick salivary peptide group 1 Pkinase PF00069.25 ORY47229.1 - 4.5e-30 104.9 0.0 1.4e-20 73.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY47229.1 - 8.1e-16 58.1 0.0 3.3e-10 39.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 ORY47229.1 - 0.0037 16.6 0.0 0.0058 16.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Homeodomain PF00046.29 ORY47230.1 - 1.9e-13 50.0 0.8 3.2e-13 49.3 0.8 1.3 1 0 0 1 1 1 1 Homeodomain DUF4246 PF14033.6 ORY47231.1 - 1e-05 24.9 0.1 1.2e-05 24.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Inovirus_Gp2 PF11726.8 ORY47231.1 - 0.009 16.0 0.3 0.012 15.6 0.3 1.1 1 0 0 1 1 1 1 Inovirus Gp2 DUF4246 PF14033.6 ORY47232.1 - 1.6e-49 169.3 0.1 3.4e-49 168.2 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_3 PF13640.6 ORY47232.1 - 0.036 15.0 0.0 0.054 14.4 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 ORY47232.1 - 0.046 14.1 0.0 0.081 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase CUB_2 PF02408.20 ORY47234.1 - 0.033 14.0 0.0 0.047 13.5 0.0 1.2 1 0 0 1 1 1 0 CUB-like domain PhoLip_ATPase_N PF16209.5 ORY47234.1 - 0.045 13.4 0.6 0.086 12.5 0.6 1.6 1 0 0 1 1 1 0 Phospholipid-translocating ATPase N-terminal DUF1322 PF07032.11 ORY47234.1 - 0.049 14.2 0.2 0.11 13.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1322) Pep1_7 PF17232.2 ORY47235.1 - 0.013 15.9 0.0 0.057 13.9 0.0 2.2 1 0 0 1 1 1 0 Elicitor peptide 1-7 ABC_tran PF00005.27 ORY47236.1 - 4.7e-17 62.8 0.0 1.1e-16 61.6 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY47236.1 - 7.7e-13 48.9 2.6 1.4e-06 28.4 0.0 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY47236.1 - 5.7e-05 22.8 0.3 0.00014 21.5 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 ORY47236.1 - 0.00044 19.9 0.0 0.00086 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 ORY47236.1 - 0.00068 19.4 0.1 0.0015 18.3 0.1 1.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 ORY47236.1 - 0.0014 19.1 0.1 0.0028 18.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY47236.1 - 0.0015 18.9 0.0 0.0032 17.9 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.19 ORY47236.1 - 0.0016 17.9 0.1 0.71 9.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 ORY47236.1 - 0.0089 16.0 0.3 0.82 9.7 0.1 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 ORY47236.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 ORY47236.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.29 ORY47236.1 - 0.1 13.0 0.1 0.35 11.3 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 ORY47236.1 - 0.14 12.3 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 ORY47236.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.12 ORY47236.1 - 0.14 11.4 0.1 0.28 10.4 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 ORY47236.1 - 0.18 12.0 1.4 0.31 11.3 0.2 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ORY47236.1 - 0.32 11.2 1.6 0.44 10.8 0.2 2.1 2 1 0 2 2 2 0 AAA domain DUF5550 PF17704.1 ORY47237.1 - 0.045 13.9 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5550) dCMP_cyt_deam_1 PF00383.23 ORY47238.1 - 7e-05 22.6 0.1 0.00017 21.4 0.1 1.6 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF4153 PF13687.6 ORY47239.1 - 0.024 14.2 0.4 0.024 14.2 0.4 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4153) Cyclin PF08613.11 ORY47241.1 - 1.9e-05 25.1 0.0 3.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin RhoGAP PF00620.27 ORY47242.1 - 4.3e-35 120.8 0.0 6.6e-35 120.2 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 ORY47242.1 - 2.5e-24 86.0 0.2 5e-24 85.0 0.2 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 ORY47242.1 - 9.9e-07 28.6 0.2 1.7e-06 27.9 0.2 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain OPT PF03169.15 ORY47245.1 - 6e-122 408.3 50.7 7e-122 408.1 50.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2109 PF09882.9 ORY47245.1 - 0.98 9.5 7.6 0.3 11.1 1.5 2.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) Sel1 PF08238.12 ORY47246.1 - 4.6e-54 179.6 22.5 8.7e-09 35.8 0.0 7.6 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.6 ORY47246.1 - 0.0082 16.7 7.3 17 6.3 0.2 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY47246.1 - 0.032 14.5 1.5 0.14 12.4 0.5 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 SPOUT_MTase_2 PF14419.6 ORY47247.1 - 0.15 11.4 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 AF2226-like SPOUT RNA Methylase fused to THUMP Nramp PF01566.18 ORY47248.1 - 6.9e-103 344.4 19.2 2.3e-62 211.0 4.1 3.3 3 0 0 3 3 3 3 Natural resistance-associated macrophage protein TPT PF03151.16 ORY47249.1 - 5.4e-58 196.6 21.7 6.5e-58 196.4 21.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORY47249.1 - 1.3e-10 41.5 29.5 5.2e-07 29.9 7.0 2.3 2 0 0 2 2 2 2 EamA-like transporter family AtpR PF12966.7 ORY47249.1 - 0.97 9.9 6.5 0.22 12.0 1.6 2.4 2 0 0 2 2 2 0 N-ATPase, AtpR subunit Abhydrolase_1 PF00561.20 ORY47250.1 - 9.2e-18 64.8 0.2 2.8e-17 63.2 0.2 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY47250.1 - 7.1e-13 49.7 0.1 1e-12 49.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY47250.1 - 2.9e-10 39.8 0.0 1.2e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ndr PF03096.14 ORY47250.1 - 0.0037 16.0 0.0 0.006 15.3 0.0 1.3 1 0 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.7 ORY47250.1 - 0.011 15.5 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF1057 PF06342.12 ORY47250.1 - 0.094 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Lipase_3 PF01764.25 ORY47250.1 - 0.13 12.1 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.11 ORY47250.1 - 0.28 10.5 0.3 1.1 8.5 0.0 2.1 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) RuvC PF02075.17 ORY47251.1 - 0.002 18.0 0.0 0.0052 16.7 0.0 1.6 1 0 0 1 1 1 1 Crossover junction endodeoxyribonuclease RuvC ICAP-1_inte_bdg PF10480.9 ORY47253.1 - 0.029 14.3 0.3 0.052 13.6 0.3 1.3 1 0 0 1 1 1 0 Beta-1 integrin binding protein DUF4246 PF14033.6 ORY47254.1 - 5.2e-112 375.2 0.0 6.1e-112 375.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 ORY47254.1 - 0.074 13.5 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 ORY47254.1 - 0.1 13.5 0.0 0.26 12.2 0.0 1.8 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily VIT_2 PF13757.6 ORY47254.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain DUF4246 PF14033.6 ORY47255.1 - 9e-111 371.2 0.3 1.1e-110 370.9 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) DXP_redisom_C PF08436.12 ORY47255.1 - 0.029 14.5 0.0 0.25 11.5 0.0 2.4 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain Histone PF00125.24 ORY47256.1 - 3.5e-52 176.2 1.9 3.9e-52 176.1 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORY47256.1 - 5.2e-05 23.3 0.3 9e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 ORY47256.1 - 6.9e-05 23.2 0.0 0.0001 22.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 ORY47256.1 - 0.00019 22.0 1.2 0.00023 21.8 1.2 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 ORY47256.1 - 0.018 15.3 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY47256.1 - 0.13 12.3 0.1 0.23 11.6 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 ORY47257.1 - 2.5e-08 34.0 0.1 3e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 ORY47257.1 - 5.9e-05 23.1 0.1 8.6e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 ORY47257.1 - 0.0001 22.6 0.1 0.00014 22.2 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 ORY47257.1 - 0.0002 21.7 0.2 0.00023 21.6 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY47257.1 - 0.00034 20.8 0.1 0.00068 19.9 0.0 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY47257.1 - 0.02 14.9 0.0 0.023 14.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORY47257.1 - 0.058 13.4 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 ORY47257.1 - 0.17 12.4 0.0 0.34 11.5 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A UPF0137 PF03677.13 ORY47257.1 - 0.2 11.4 0.1 0.24 11.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Tropomyosin_1 PF12718.7 ORY47261.1 - 9.1e-17 61.5 25.6 3.4e-10 40.2 8.6 2.1 1 1 1 2 2 2 2 Tropomyosin like Tropomyosin PF00261.20 ORY47261.1 - 3.3e-09 36.5 23.2 4.1e-09 36.2 23.2 1.1 1 0 0 1 1 1 1 Tropomyosin Tup_N PF08581.10 ORY47261.1 - 9.2e-06 25.9 14.6 0.0044 17.3 3.2 2.1 1 1 1 2 2 2 2 Tup N-terminal Laminin_II PF06009.12 ORY47261.1 - 8.4e-05 22.6 11.4 9.7e-05 22.4 10.8 1.5 1 1 0 1 1 1 1 Laminin Domain II Filament PF00038.21 ORY47261.1 - 0.00053 19.7 16.4 0.029 14.0 9.4 1.9 1 1 0 1 1 1 1 Intermediate filament protein GAS PF13851.6 ORY47261.1 - 0.0013 18.1 20.0 0.0016 17.8 20.0 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF16 PF01519.16 ORY47261.1 - 0.0014 19.1 14.7 0.0017 18.8 6.1 2.0 1 1 1 2 2 2 1 Protein of unknown function DUF16 ERM PF00769.19 ORY47261.1 - 0.0041 17.0 11.0 0.0041 17.0 11.0 1.9 1 1 1 2 2 2 1 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.12 ORY47261.1 - 0.005 16.9 24.2 0.071 13.2 9.1 2.2 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein DUF724 PF05266.14 ORY47261.1 - 0.0085 15.9 15.2 0.024 14.5 15.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF724) CEP209_CC5 PF16574.5 ORY47261.1 - 0.009 16.2 16.3 0.19 11.9 3.6 2.1 1 1 1 2 2 2 2 Coiled-coil region of centrosome protein CE290 Fib_alpha PF08702.10 ORY47261.1 - 0.011 16.0 9.4 0.011 16.0 9.4 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family ATG16 PF08614.11 ORY47261.1 - 0.031 14.5 24.2 0.14 12.4 9.5 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF641 PF04859.12 ORY47261.1 - 0.035 14.4 5.2 0.035 14.4 5.2 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) MscS_porin PF12795.7 ORY47261.1 - 0.05 13.1 19.7 0.11 12.0 19.6 1.6 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF4201 PF13870.6 ORY47261.1 - 0.06 13.1 17.2 0.086 12.6 17.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DivIC PF04977.15 ORY47261.1 - 0.065 13.0 17.8 0.12 12.1 3.8 2.8 2 1 1 3 3 3 0 Septum formation initiator M PF02370.16 ORY47261.1 - 0.072 13.7 2.1 0.072 13.7 2.1 4.6 4 2 2 6 6 4 0 M protein repeat Spc7 PF08317.11 ORY47261.1 - 0.076 11.9 21.1 0.1 11.5 9.4 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 ORY47261.1 - 0.091 12.8 25.1 0.068 13.2 12.4 2.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF3584 PF12128.8 ORY47261.1 - 0.093 10.2 18.7 0.1 10.1 18.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ADIP PF11559.8 ORY47261.1 - 0.095 12.8 22.0 0.25 11.4 8.5 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Lectin_N PF03954.14 ORY47261.1 - 0.1 12.3 11.3 1.4 8.7 3.3 2.8 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain CLZ PF16526.5 ORY47261.1 - 0.12 12.8 17.7 0.17 12.3 3.9 2.7 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HAUS-augmin3 PF14932.6 ORY47261.1 - 0.13 11.8 18.1 0.3 10.6 17.9 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 CENP-F_leu_zip PF10473.9 ORY47261.1 - 0.13 12.3 22.6 0.65 10.0 16.5 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HrpB7 PF09486.10 ORY47261.1 - 0.14 12.5 17.4 0.37 11.2 7.7 2.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF4200 PF13863.6 ORY47261.1 - 0.17 12.3 23.1 1.2 9.5 9.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF3450 PF11932.8 ORY47261.1 - 0.18 11.1 18.3 0.89 8.8 7.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4795 PF16043.5 ORY47261.1 - 0.2 11.2 15.5 0.075 12.6 12.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Troponin PF00992.20 ORY47261.1 - 0.26 11.6 19.9 0.66 10.3 6.2 2.4 1 1 0 1 1 1 0 Troponin WXG100 PF06013.12 ORY47261.1 - 0.26 11.5 5.9 3 8.1 0.6 2.6 1 1 1 3 3 3 0 Proteins of 100 residues with WXG Noelin-1 PF12308.8 ORY47261.1 - 0.27 11.2 4.4 0.5 10.4 3.3 1.9 1 1 1 2 2 2 0 Neurogenesis glycoprotein SlyX PF04102.12 ORY47261.1 - 0.29 11.8 13.5 0.24 12.0 4.9 2.7 1 1 2 3 3 3 0 SlyX TMCO5 PF14992.6 ORY47261.1 - 0.37 10.3 14.2 0.38 10.3 13.7 1.4 1 1 0 1 1 1 0 TMCO5 family Nup54 PF13874.6 ORY47261.1 - 0.38 10.9 12.6 0.41 10.7 11.4 1.6 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Jnk-SapK_ap_N PF09744.9 ORY47261.1 - 0.41 10.9 20.9 0.99 9.6 20.9 1.6 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 KASH_CCD PF14662.6 ORY47261.1 - 0.42 10.4 20.1 0.072 12.9 6.0 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DHR10 PF18595.1 ORY47261.1 - 0.44 10.6 25.5 0.71 9.9 11.2 2.7 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain DUF4407 PF14362.6 ORY47261.1 - 0.44 9.8 15.2 0.54 9.6 15.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GrpE PF01025.19 ORY47261.1 - 0.48 10.1 18.0 1 9.0 7.1 2.3 1 1 1 2 2 2 0 GrpE DUF4472 PF14739.6 ORY47261.1 - 0.63 10.8 16.4 22 5.8 16.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) SHE3 PF17078.5 ORY47261.1 - 0.66 9.7 16.4 0.14 11.8 2.2 2.1 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 DUF4988 PF16378.5 ORY47261.1 - 0.66 9.6 4.7 6.4 6.4 0.5 2.6 2 1 1 3 3 3 0 Domain of unknown function DUF1664 PF07889.12 ORY47261.1 - 0.67 10.0 9.5 0.46 10.5 4.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Phage_GPO PF05929.11 ORY47261.1 - 0.69 9.5 13.8 0.96 9.0 13.8 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase LPP PF04728.13 ORY47261.1 - 0.7 10.3 11.6 1 9.8 0.6 3.5 1 1 1 3 3 3 0 Lipoprotein leucine-zipper DASH_Spc19 PF08287.11 ORY47261.1 - 0.77 9.6 17.8 0.33 10.8 15.0 1.7 1 1 1 2 2 2 0 Spc19 Fez1 PF06818.15 ORY47261.1 - 0.77 10.2 17.8 1.6 9.1 17.8 1.6 1 1 0 1 1 1 0 Fez1 OmpH PF03938.14 ORY47261.1 - 0.88 9.9 17.4 1.8 8.9 16.1 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Ax_dynein_light PF10211.9 ORY47261.1 - 0.9 9.4 18.6 0.47 10.4 4.3 2.3 1 1 1 2 2 2 0 Axonemal dynein light chain Phage_HK97_TLTM PF06120.11 ORY47261.1 - 0.92 8.6 14.0 0.97 8.6 14.0 1.0 1 0 0 1 1 1 0 Tail length tape measure protein Rootletin PF15035.6 ORY47261.1 - 1 9.3 17.9 1.6 8.7 16.5 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Phlebovirus_NSM PF07246.11 ORY47261.1 - 1.1 8.6 9.0 0.2 11.0 5.3 1.5 1 1 1 2 2 2 0 Phlebovirus nonstructural protein NS-M NPV_P10 PF05531.12 ORY47261.1 - 1.2 9.6 7.3 1.7 9.2 2.0 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.15 ORY47261.1 - 1.4 8.4 11.5 1.5 8.3 11.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 ORY47261.1 - 1.5 6.6 11.6 2 6.2 11.6 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6_N PF17675.1 ORY47261.1 - 2.1 8.9 26.8 9.7 6.7 26.8 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF5595 PF18077.1 ORY47261.1 - 2.2 8.4 12.5 0.31 11.2 1.7 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF5595) THOC7 PF05615.13 ORY47261.1 - 2.4 8.5 18.8 2.7 8.3 12.2 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 DUF1690 PF07956.11 ORY47261.1 - 2.8 8.4 19.5 0.22 11.9 11.7 2.0 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Spc42p PF11544.8 ORY47261.1 - 2.8 8.0 10.8 17 5.5 8.5 2.7 1 1 1 2 2 2 0 Spindle pole body component Spc42p AAA_13 PF13166.6 ORY47261.1 - 3 6.4 16.4 6.3 5.3 16.3 1.5 1 1 0 1 1 1 0 AAA domain DUF5320 PF17253.2 ORY47261.1 - 3.2 8.9 9.7 14 6.8 1.2 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5320) LPP20 PF02169.16 ORY47261.1 - 3.7 8.0 7.6 3.8 7.9 6.2 1.7 1 1 1 2 2 2 0 LPP20 lipoprotein DUF948 PF06103.11 ORY47261.1 - 3.8 7.8 8.3 0.89 9.8 3.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Cluap1 PF10234.9 ORY47261.1 - 4.2 6.7 18.4 3 7.2 6.8 2.2 1 1 1 2 2 2 0 Clusterin-associated protein-1 FUSC PF04632.12 ORY47261.1 - 4.3 5.8 6.9 4.5 5.7 6.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4140 PF13600.6 ORY47261.1 - 4.6 7.8 18.9 1.5 9.3 5.4 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) FAM76 PF16046.5 ORY47261.1 - 5.2 6.3 11.2 6.3 6.0 11.2 1.3 1 0 0 1 1 1 0 FAM76 protein HALZ PF02183.18 ORY47261.1 - 5.2 7.4 11.5 0.54 10.5 0.8 3.0 3 1 0 3 3 2 0 Homeobox associated leucine zipper Syntaxin-6_N PF09177.11 ORY47261.1 - 5.3 7.7 12.3 8.1 7.1 3.2 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Atg14 PF10186.9 ORY47261.1 - 5.8 5.9 16.6 31 3.5 16.6 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fmp27_WPPW PF10359.9 ORY47261.1 - 5.9 5.6 15.6 13 4.5 15.6 1.6 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF812 PF05667.11 ORY47261.1 - 6.2 5.6 19.7 9.4 5.0 19.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Csm1_N PF18504.1 ORY47261.1 - 6.8 7.1 18.1 0.6 10.5 4.3 3.0 2 1 1 3 3 3 0 Csm1 N-terminal domain TMPIT PF07851.13 ORY47261.1 - 9.9 5.3 12.5 24 4.0 12.5 1.7 1 1 0 1 1 1 0 TMPIT-like protein Pkinase PF00069.25 ORY47262.1 - 3e-58 197.3 0.0 1.3e-40 139.5 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY47262.1 - 1.3e-26 93.4 0.1 1.8e-17 63.5 0.1 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY47262.1 - 3.4e-07 29.9 0.0 1.9e-06 27.4 0.0 2.2 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY47262.1 - 3.7e-06 26.4 0.2 6.9e-06 25.6 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY47262.1 - 0.026 13.5 0.2 0.054 12.4 0.2 1.5 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 ORY47262.1 - 0.033 14.1 0.1 0.065 13.2 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 ORY47262.1 - 0.12 12.0 0.1 0.36 10.4 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 KRTAP PF11759.8 ORY47262.1 - 3.3 8.3 15.3 0.28 11.7 9.6 1.9 2 0 0 2 2 2 0 Keratin-associated matrix ABM PF03992.16 ORY47263.1 - 0.00032 20.7 0.1 0.00039 20.5 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase betaPIX_CC PF16523.5 ORY47264.1 - 0.0015 18.3 3.7 0.0035 17.1 3.8 1.6 1 1 0 1 1 1 1 betaPIX coiled coil Macoilin PF09726.9 ORY47264.1 - 0.004 15.8 3.9 0.0077 14.9 3.9 1.5 1 1 0 1 1 1 1 Macoilin family CCDC144C PF14915.6 ORY47264.1 - 0.0042 16.2 2.8 0.0066 15.6 2.8 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region PI3K_P85_iSH2 PF16454.5 ORY47264.1 - 0.011 15.3 2.6 0.019 14.6 2.6 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain CENP-F_leu_zip PF10473.9 ORY47264.1 - 0.018 15.0 4.1 0.03 14.3 4.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 ORY47264.1 - 0.019 15.5 2.0 0.032 14.8 2.0 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Tropomyosin PF00261.20 ORY47264.1 - 0.035 13.5 2.0 0.048 13.0 2.0 1.2 1 0 0 1 1 1 0 Tropomyosin EzrA PF06160.12 ORY47264.1 - 0.048 11.8 1.3 0.07 11.3 1.3 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Rab5-bind PF09311.11 ORY47264.1 - 0.052 12.9 3.6 0.076 12.4 3.6 1.1 1 0 0 1 1 1 0 Rabaptin-like protein DUF4200 PF13863.6 ORY47264.1 - 0.087 13.2 2.4 0.16 12.4 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Nnf1 PF03980.14 ORY47264.1 - 0.09 13.2 2.7 0.41 11.1 2.7 2.0 1 1 0 1 1 1 0 Nnf1 DDE_Tnp_IS1 PF03400.13 ORY47264.1 - 0.13 12.6 0.2 0.23 11.8 0.2 1.3 1 0 0 1 1 1 0 IS1 transposase Mto2_bdg PF12808.7 ORY47264.1 - 0.62 10.4 4.4 0.75 10.1 2.4 2.1 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Lzipper-MIP1 PF14389.6 ORY47264.1 - 1.7 9.0 6.6 0.15 12.3 0.7 2.4 2 1 0 2 2 1 0 Leucine-zipper of ternary complex factor MIP1 Glyoxalase PF00903.25 ORY47265.1 - 2e-11 44.1 0.0 0.00015 22.0 0.1 2.6 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ORY47265.1 - 2.9e-07 30.7 0.0 0.012 15.8 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 ORY47265.1 - 0.0085 16.2 0.0 0.71 10.0 0.0 2.7 2 1 0 2 2 2 1 Glyoxalase-like domain Fringe PF02434.16 ORY47266.1 - 1e-09 38.2 0.0 2.6e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Fringe-like DUF604 PF04646.12 ORY47266.1 - 1.5e-07 31.1 0.2 4.3e-07 29.6 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF604 PAN_1 PF00024.26 ORY47266.1 - 2.3e-05 24.3 0.3 4.7e-05 23.3 0.3 1.5 1 0 0 1 1 1 1 PAN domain Galactosyl_T PF01762.21 ORY47266.1 - 0.03 14.2 0.0 0.072 12.9 0.0 1.6 2 0 0 2 2 2 0 Galactosyltransferase PAN_4 PF14295.6 ORY47266.1 - 0.043 13.7 0.3 0.1 12.5 0.3 1.6 1 0 0 1 1 1 0 PAN domain AAA PF00004.29 ORY47267.1 - 6.5e-50 169.0 0.0 6e-43 146.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY47267.1 - 1.8e-11 43.7 0.1 3.9e-11 42.6 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain IstB_IS21 PF01695.17 ORY47267.1 - 4.3e-07 29.8 0.0 2.4e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 ORY47267.1 - 1.7e-06 28.3 0.0 5.3e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 ORY47267.1 - 2.2e-06 28.2 5.2 4.4e-05 23.9 1.1 3.4 2 2 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 ORY47267.1 - 5.6e-05 23.2 0.0 0.00089 19.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY47267.1 - 0.00052 20.3 0.3 0.11 12.8 0.6 2.9 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 ORY47267.1 - 0.002 17.5 0.0 0.017 14.5 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 ORY47267.1 - 0.0043 16.8 0.1 0.059 13.1 0.0 2.7 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 ORY47267.1 - 0.0049 16.1 0.0 0.0093 15.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 ORY47267.1 - 0.0051 17.0 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 ORY47267.1 - 0.0054 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_25 PF13481.6 ORY47267.1 - 0.0062 16.1 0.1 0.023 14.3 0.0 1.9 3 0 0 3 3 2 1 AAA domain AAA_3 PF07726.11 ORY47267.1 - 0.0066 16.3 0.0 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORY47267.1 - 0.0077 16.6 0.0 0.023 15.1 0.0 1.9 1 0 0 1 1 1 1 RNA helicase Sigma54_activ_2 PF14532.6 ORY47267.1 - 0.011 15.8 0.0 0.18 11.9 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 ORY47267.1 - 0.012 15.6 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY47267.1 - 0.014 14.9 0.0 0.076 12.5 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 ORY47267.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 ORY47267.1 - 0.029 14.1 0.0 0.32 10.7 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 ORY47267.1 - 0.03 14.2 0.2 0.11 12.5 0.2 2.0 1 1 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 ORY47267.1 - 0.044 14.3 0.0 0.091 13.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.17 ORY47267.1 - 0.047 12.8 0.1 0.12 11.4 0.0 1.6 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 ORY47267.1 - 0.048 14.2 0.0 0.15 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 ORY47267.1 - 0.058 12.6 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.6 ORY47267.1 - 0.096 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 ORY47267.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 ORY47267.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Urm1 PF09138.11 ORY47270.1 - 1.3e-34 118.4 0.1 1.4e-34 118.3 0.1 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 ORY47270.1 - 1.2e-05 25.9 0.0 1.4e-05 25.6 0.0 1.1 1 0 0 1 1 1 1 ThiS family DnaJ PF00226.31 ORY47271.1 - 2.6e-07 30.6 0.1 3.6e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain DUF4246 PF14033.6 ORY47272.1 - 2.1e-85 287.5 0.0 2.7e-85 287.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) Cas9_REC PF16592.5 ORY47272.1 - 0.15 10.8 0.0 1.5 7.4 0.0 2.0 2 0 0 2 2 2 0 REC lobe of CRISPR-associated endonuclease Cas9 PAN_1 PF00024.26 ORY47273.1 - 2.3e-27 94.7 2.5 1.9e-08 34.2 0.2 4.4 3 1 1 4 4 4 4 PAN domain PAN_4 PF14295.6 ORY47273.1 - 7.3e-17 61.0 19.5 6e-05 22.9 0.5 4.7 5 0 0 5 5 5 4 PAN domain PAN_2 PF08276.11 ORY47273.1 - 0.016 15.3 22.2 0.36 11.0 0.6 4.7 5 0 0 5 5 5 0 PAN-like domain TatD_DNase PF01026.21 ORY47275.1 - 3.5e-30 105.2 0.0 4.3e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 ORY47275.1 - 0.0045 16.8 0.2 0.017 14.9 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase Pmp3 PF01679.17 ORY47276.1 - 9.5e-17 60.9 5.1 1.2e-16 60.6 5.1 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF4191 PF13829.6 ORY47276.1 - 0.052 12.9 0.4 0.056 12.8 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) CENP-T_C PF15511.6 ORY47277.1 - 2.5e-08 34.0 0.1 3e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 ORY47277.1 - 5.9e-05 23.1 0.1 8.6e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 ORY47277.1 - 0.0001 22.6 0.1 0.00014 22.2 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 ORY47277.1 - 0.0002 21.7 0.2 0.00023 21.6 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY47277.1 - 0.00034 20.8 0.1 0.00068 19.9 0.0 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY47277.1 - 0.02 14.9 0.0 0.023 14.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORY47277.1 - 0.058 13.4 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 ORY47277.1 - 0.17 12.4 0.0 0.34 11.5 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A UPF0137 PF03677.13 ORY47277.1 - 0.2 11.4 0.1 0.24 11.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 ORY47278.1 - 3.5e-52 176.2 1.9 3.9e-52 176.1 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORY47278.1 - 5.2e-05 23.3 0.3 9e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 ORY47278.1 - 6.9e-05 23.2 0.0 0.0001 22.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 ORY47278.1 - 0.00019 22.0 1.2 0.00023 21.8 1.2 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 ORY47278.1 - 0.018 15.3 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY47278.1 - 0.13 12.3 0.1 0.23 11.6 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit DUF4246 PF14033.6 ORY47279.1 - 4.6e-113 378.7 0.1 5.5e-113 378.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_3 PF13640.6 ORY47279.1 - 0.03 15.2 0.0 0.064 14.2 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 ORY47279.1 - 0.06 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase DUF3295 PF11702.8 ORY47279.1 - 0.24 10.7 1.8 0.38 10.1 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Aldose_epim PF01263.20 ORY47281.1 - 2.1e-36 125.8 0.0 2.3e-36 125.6 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase PIF2 PF04631.12 ORY47281.1 - 0.052 12.4 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Per os infectivity factor 2 SH3_1 PF00018.28 ORY47282.1 - 4e-11 42.3 0.0 1.5e-06 27.7 0.0 2.2 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 ORY47282.1 - 4e-10 39.4 0.0 0.00071 19.4 0.0 2.2 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 ORY47282.1 - 1.7e-06 27.6 0.2 0.00065 19.3 0.1 2.2 2 0 0 2 2 2 2 Variant SH3 domain DUF5348 PF17295.2 ORY47282.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5348) KGK PF08872.10 ORY47282.1 - 0.18 12.3 0.0 0.31 11.5 0.0 1.4 1 0 0 1 1 1 0 KGK domain Dus PF01207.17 ORY47283.1 - 3e-15 56.1 0.0 3.3e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) PucR PF07905.11 ORY47283.1 - 0.06 13.6 0.0 0.062 13.6 0.0 1.2 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Dus PF01207.17 ORY47284.1 - 0.19 10.8 0.0 0.36 9.9 0.0 1.5 1 1 0 1 1 1 0 Dihydrouridine synthase (Dus) Glyco_hydro_35 PF01301.19 ORY47285.1 - 1.7e-62 211.9 0.2 5.6e-62 210.2 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 ORY47285.1 - 3.3e-06 27.6 0.0 0.0043 17.6 0.0 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain Glyco_hydro_42 PF02449.15 ORY47285.1 - 3.4e-06 26.6 0.0 6.8e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase Cellulase PF00150.18 ORY47285.1 - 0.0063 16.0 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Amidohydro_2 PF04909.14 ORY47285.1 - 0.06 13.1 0.1 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Amidohydrolase SH3_9 PF14604.6 ORY47286.1 - 2.3e-13 49.8 0.6 3.3e-07 30.1 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain SH3_1 PF00018.28 ORY47286.1 - 2.2e-10 40.0 0.1 9.3e-05 22.0 0.0 2.6 3 0 0 3 3 3 2 SH3 domain SH3_2 PF07653.17 ORY47286.1 - 8e-07 28.6 0.7 0.0092 15.6 0.1 2.5 2 1 0 2 2 2 2 Variant SH3 domain Torus PF16131.5 ORY47287.1 - 0.0011 19.7 3.4 0.0022 18.7 3.1 1.8 1 1 0 1 1 1 1 Torus domain zf-CCCH PF00642.24 ORY47287.1 - 0.21 11.6 6.7 0.37 10.8 6.7 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY47287.1 - 8.6 6.6 16.2 0.86 9.7 11.3 1.8 2 0 0 2 2 2 0 Zinc finger domain SH3_9 PF14604.6 ORY47289.1 - 7e-11 41.8 0.0 1.1e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY47289.1 - 8.3e-10 38.1 0.0 1.4e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY47289.1 - 1.5e-07 31.0 0.0 2.9e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Podoplanin PF05808.11 ORY47289.1 - 3.9e-06 27.1 0.3 3.9e-06 27.1 0.3 1.7 2 0 0 2 2 2 1 Podoplanin SKG6 PF08693.10 ORY47289.1 - 0.15 11.5 2.0 0.54 9.7 2.0 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMV_coat PF00721.21 ORY47289.1 - 9.9 6.0 8.9 1.6 8.6 1.9 2.7 3 0 0 3 3 3 0 Virus coat protein (TMV like) AAA_16 PF13191.6 ORY47290.1 - 0.00014 22.3 0.0 0.00043 20.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 ORY47290.1 - 0.00014 21.8 0.0 0.00058 19.8 0.0 1.9 1 1 0 1 1 1 1 NACHT domain AAA_26 PF13500.6 ORY47290.1 - 0.068 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 ORY47290.1 - 0.072 13.1 0.0 0.21 11.6 0.0 1.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain SH3_1 PF00018.28 ORY47291.1 - 7.5e-05 22.3 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY47291.1 - 0.00056 19.7 0.0 0.00091 19.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY47291.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Syndecan PF01034.20 ORY47291.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain FERM_M PF00373.18 ORY47292.1 - 4.3e-15 56.2 0.0 7e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 FERM central domain partial_CstF PF15861.5 ORY47292.1 - 0.077 12.8 0.3 0.17 11.7 0.3 1.5 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain DUF4131 PF13567.6 ORY47294.1 - 0.037 13.7 0.0 0.051 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) HHH_5 PF14520.6 ORY47295.1 - 0.0062 17.1 0.1 0.47 11.1 0.0 2.2 2 0 0 2 2 2 2 Helix-hairpin-helix domain Pkinase PF00069.25 ORY47297.1 - 8.8e-70 235.1 0.0 1.1e-69 234.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY47297.1 - 1.1e-32 113.4 0.0 2e-32 112.5 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 ORY47297.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Acyltransferase PF01553.21 ORY47298.1 - 1.3e-19 70.2 0.0 2.5e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 ORY47298.1 - 0.0076 16.3 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus Cyclin PF08613.11 ORY47300.1 - 5.2e-09 36.7 0.5 1.4e-08 35.3 0.5 2.0 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY47300.1 - 0.0037 17.0 0.3 0.054 13.2 0.0 2.6 3 0 0 3 3 3 1 Cyclin, N-terminal domain RRM_1 PF00076.22 ORY47301.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRMT5 PF05185.16 ORY47303.1 - 3e-65 219.3 0.0 5e-65 218.6 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 ORY47303.1 - 4.7e-49 166.7 0.0 7.7e-49 165.9 0.0 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PRMT5_TIM PF17285.2 ORY47303.1 - 7.8e-29 100.6 0.0 1.3e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 PRMT5 TIM barrel domain Methyltransf_25 PF13649.6 ORY47303.1 - 0.00027 21.6 0.0 0.001 19.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY47303.1 - 0.024 15.3 0.0 0.077 13.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain F-box-like PF12937.7 ORY47306.1 - 0.0048 16.8 0.1 0.0048 16.8 0.1 2.9 3 1 0 3 3 3 1 F-box-like F-box PF00646.33 ORY47306.1 - 0.029 14.2 0.7 0.11 12.4 0.7 2.0 1 0 0 1 1 1 0 F-box domain DUF4246 PF14033.6 ORY47307.1 - 1.6e-90 304.4 0.0 4.4e-63 214.0 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_3 PF13640.6 ORY47307.1 - 0.051 14.5 0.0 0.11 13.4 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 ORY47307.1 - 0.079 13.4 0.0 0.18 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Crystall_4 PF17945.1 ORY47307.1 - 0.085 13.3 0.0 0.31 11.5 0.0 2.0 2 0 0 2 2 2 0 Beta/Gamma crystallin Ribonuclease_T2 PF00445.18 ORY47308.1 - 1.1e-22 81.2 0.2 1.3e-22 81.0 0.2 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family adh_short PF00106.25 ORY47309.1 - 2.4e-26 92.4 0.0 1.7e-24 86.4 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY47309.1 - 4.7e-13 49.2 0.0 1.5e-12 47.6 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY47309.1 - 3.1e-07 30.5 0.0 7.6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY47309.1 - 0.00045 19.8 0.0 0.00072 19.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY47309.1 - 0.062 12.4 0.0 0.097 11.8 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 ORY47309.1 - 0.085 13.1 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain KTI12 PF08433.10 ORY47310.1 - 2.4e-66 224.0 0.0 2.8e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 ORY47310.1 - 6.1e-06 26.4 0.0 1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY47310.1 - 0.11 12.8 0.0 0.21 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain 6PF2K PF01591.18 ORY47310.1 - 0.12 11.6 0.1 0.19 11.0 0.1 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase Coprogen_oxidas PF01218.18 ORY47312.1 - 0.015 14.0 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Coproporphyrinogen III oxidase CAML PF14963.6 ORY47312.1 - 0.13 12.3 1.8 0.3 11.2 1.8 1.6 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand CAML PF14963.6 ORY47313.1 - 0.07 13.2 1.1 0.13 12.4 1.1 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Coprogen_oxidas PF01218.18 ORY47313.1 - 0.072 11.8 0.0 0.094 11.4 0.0 1.2 1 0 0 1 1 1 0 Coproporphyrinogen III oxidase Aminotran_1_2 PF00155.21 ORY47314.1 - 1.4e-77 261.4 0.1 1.7e-77 261.1 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ORY47314.1 - 1.3e-05 23.9 0.1 2e-05 23.3 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 ORY47314.1 - 0.00015 21.2 0.6 0.0002 20.8 0.6 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Preseq_ALAS PF09029.10 ORY47314.1 - 0.00019 21.9 1.2 0.00042 20.8 1.2 1.6 1 0 0 1 1 1 1 5-aminolevulinate synthase presequence Aminotran_5 PF00266.19 ORY47314.1 - 0.00044 19.3 0.1 0.00072 18.6 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Spc7 PF08317.11 ORY47317.1 - 0.021 13.7 5.2 0.058 12.3 5.2 1.7 1 0 0 1 1 1 0 Spc7 kinetochore protein JIP_LZII PF16471.5 ORY47317.1 - 1.4 9.1 9.9 0.4 10.9 6.1 2.1 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II BRE1 PF08647.11 ORY47317.1 - 3.8 7.6 12.5 0.33 11.0 5.0 2.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF3958 PF13125.6 ORY47317.1 - 4.2 7.6 9.5 1.9 8.8 1.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3958) Tim17 PF02466.19 ORY47318.1 - 3.5e-08 33.8 6.0 1.8e-07 31.5 2.7 2.1 1 1 1 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family Mg_trans_NIPA PF05653.14 ORY47319.1 - 5.8e-83 278.4 20.2 7.8e-83 278.0 20.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORY47319.1 - 1.9e-08 34.5 37.2 3.5e-07 30.5 5.8 3.3 3 0 0 3 3 3 3 EamA-like transporter family HR_lesion PF05514.11 ORY47319.1 - 1.3 9.2 7.3 0.14 12.3 1.1 2.5 2 1 0 2 2 2 0 HR-like lesion-inducing SLATT_fungal PF18142.1 ORY47319.1 - 3.4 7.7 4.6 12 5.9 1.3 2.6 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Pkinase PF00069.25 ORY47320.1 - 1.3e-74 250.9 0.0 1.6e-74 250.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY47320.1 - 4e-33 114.8 0.0 5.2e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY47320.1 - 1.1e-05 24.9 0.1 4.5e-05 22.9 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 ORY47320.1 - 1.8e-05 24.2 0.0 3.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY47320.1 - 0.00049 19.2 0.6 0.00086 18.3 0.6 1.4 1 1 0 1 1 1 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 ORY47320.1 - 0.00088 18.9 0.2 0.0024 17.4 0.0 1.7 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 ORY47320.1 - 0.0013 17.6 0.0 0.0033 16.3 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 ORY47320.1 - 0.024 14.2 0.8 0.049 13.2 0.8 1.5 1 1 0 1 1 1 0 RIO1 family APH PF01636.23 ORY47320.1 - 0.025 14.5 0.0 0.06 13.3 0.0 1.6 1 1 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 ORY47320.1 - 0.04 13.5 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 ORY47321.1 - 1.8e-139 463.5 0.0 1.1e-71 241.3 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY47321.1 - 6.1e-61 206.0 0.0 4.5e-32 111.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY47321.1 - 1.5e-11 44.2 0.0 4.6e-05 22.9 0.0 2.5 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 ORY47321.1 - 6.4e-10 38.7 0.1 0.00015 21.2 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY47321.1 - 2.7e-08 33.0 0.7 0.0014 17.4 0.0 3.1 2 1 0 3 3 3 2 Fungal protein kinase Haspin_kinase PF12330.8 ORY47321.1 - 6.7e-06 25.3 0.7 0.015 14.3 0.1 2.1 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 ORY47321.1 - 8.2e-06 25.9 0.0 0.11 12.4 0.0 2.7 2 1 0 2 2 2 2 Phosphotransferase enzyme family PACT_coil_coil PF10495.9 ORY47321.1 - 4.5e-05 23.9 0.3 0.43 11.2 0.1 2.6 2 0 0 2 2 2 2 Pericentrin-AKAP-450 domain of centrosomal targeting protein YrbL-PhoP_reg PF10707.9 ORY47321.1 - 5.4e-05 22.8 0.3 0.21 11.1 0.0 2.4 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL RIO1 PF01163.22 ORY47321.1 - 0.00028 20.5 0.8 0.046 13.3 0.1 2.2 2 0 0 2 2 2 2 RIO1 family Pox_ser-thr_kin PF05445.11 ORY47321.1 - 0.00067 18.7 0.6 0.66 8.9 0.2 2.2 2 0 0 2 2 2 2 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.20 ORY47321.1 - 0.0083 15.7 0.2 3.3 7.2 0.0 2.5 2 0 0 2 2 2 2 Choline/ethanolamine kinase FTA2 PF13095.6 ORY47321.1 - 0.058 13.0 0.6 11 5.6 0.0 2.6 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Rota_NSP4 PF01452.16 ORY47321.1 - 0.1 12.3 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Rotavirus non structural protein Pkinase PF00069.25 ORY47322.1 - 3.9e-25 88.7 0.4 1.1e-11 44.7 0.1 3.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY47322.1 - 5.2e-14 52.2 0.0 5.9e-05 22.5 0.0 3.7 3 1 0 3 3 3 3 Protein tyrosine kinase Pox_A_type_inc PF04508.12 ORY47322.1 - 0.043 13.7 2.8 0.13 12.2 2.8 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat XhlA PF10779.9 ORY47322.1 - 0.45 10.8 2.7 0.93 9.7 0.9 2.3 2 0 0 2 2 2 0 Haemolysin XhlA zf-H2C2_2 PF13465.6 ORY47323.1 - 1.7e-09 37.7 3.5 1.3e-05 25.4 0.8 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY47323.1 - 1.9e-09 37.4 8.0 9.5e-07 28.9 2.7 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 ORY47323.1 - 6.6e-07 29.5 0.5 1.2e-06 28.6 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 ORY47323.1 - 6.5e-06 26.5 5.9 1.3e-05 25.6 1.6 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY47323.1 - 7.7e-05 22.9 0.1 0.00013 22.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY47323.1 - 0.00018 21.4 0.4 0.00029 20.7 0.4 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 ORY47323.1 - 0.0073 16.6 0.1 0.0095 16.3 0.1 1.2 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Zn_ribbon_SprT PF17283.2 ORY47323.1 - 0.023 14.6 1.3 0.023 14.6 1.3 1.8 1 1 1 2 2 2 0 SprT-like zinc ribbon domain zf-DNA_Pol PF08996.10 ORY47323.1 - 0.084 12.6 0.6 0.095 12.4 0.6 1.0 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger ABC2_membrane PF01061.24 ORY47324.1 - 2.9e-22 79.1 14.1 2.9e-22 79.1 14.1 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC2_membrane_3 PF12698.7 ORY47324.1 - 0.018 14.1 16.8 0.029 13.5 16.8 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein ABC_tran PF00005.27 ORY47325.1 - 3e-09 37.5 0.1 4.1e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 ORY47325.1 - 0.21 11.0 0.1 0.24 10.8 0.1 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain DWNN PF08783.11 ORY47326.1 - 0.013 15.7 0.6 0.044 14.1 0.1 2.0 2 0 0 2 2 2 0 DWNN domain DUF3527 PF12043.8 ORY47326.1 - 0.67 9.5 10.6 0.23 11.0 1.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3527) adh_short PF00106.25 ORY47328.1 - 7.6e-20 71.2 0.0 9e-20 71.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY47328.1 - 9.4e-11 41.7 0.0 1.2e-10 41.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY47328.1 - 9.5e-05 22.4 0.0 0.0001 22.2 0.0 1.1 1 0 0 1 1 1 1 KR domain Synaptobrevin PF00957.21 ORY47329.1 - 1.1e-26 92.4 3.1 1.2e-26 92.3 3.1 1.0 1 0 0 1 1 1 1 Synaptobrevin Pex24p PF06398.11 ORY47329.1 - 0.016 14.3 0.0 0.016 14.2 0.0 1.0 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin LRRC37AB_C PF14914.6 ORY47329.1 - 0.033 14.1 0.5 0.036 14.0 0.5 1.1 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain T4bSS_IcmS PF12608.8 ORY47329.1 - 0.071 13.4 0.0 0.086 13.2 0.0 1.2 1 0 0 1 1 1 0 Type IVb secretion, IcmS, effector-recruitment Orf78 PF06024.12 ORY47329.1 - 0.082 13.2 0.3 0.096 13.0 0.3 1.1 1 0 0 1 1 1 0 Orf78 (ac78) Amnionless PF14828.6 ORY47329.1 - 0.13 11.0 0.2 0.14 11.0 0.2 1.0 1 0 0 1 1 1 0 Amnionless Ank_2 PF12796.7 ORY47331.1 - 8.3e-21 74.4 4.2 3.7e-10 40.3 1.0 3.1 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY47331.1 - 1.4e-15 55.8 2.2 0.082 13.5 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 ORY47331.1 - 6.1e-14 52.2 6.7 5.2e-05 23.7 0.0 5.4 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY47331.1 - 1.4e-13 50.7 3.7 0.0066 16.7 0.0 5.9 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY47331.1 - 1.1e-09 38.2 4.8 0.12 12.9 0.1 5.5 5 0 0 5 5 5 4 Ankyrin repeat MiaE_2 PF13794.6 ORY47331.1 - 0.051 13.3 0.0 0.42 10.3 0.0 2.1 2 0 0 2 2 2 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like LysM PF01476.20 ORY47332.1 - 7.6e-10 38.7 0.0 0.019 15.0 0.0 3.3 3 0 0 3 3 3 3 LysM domain Mucin PF01456.17 ORY47332.1 - 7.6e-05 22.7 33.0 7.6e-05 22.7 33.0 3.0 3 0 0 3 3 3 1 Mucin-like glycoprotein Usp PF00582.26 ORY47333.1 - 2.9e-26 92.6 0.0 3.9e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family DUF3552 PF12072.8 ORY47336.1 - 0.17 11.3 2.9 0.23 10.9 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) Beta-lactamase PF00144.24 ORY47337.1 - 2.7e-13 49.9 0.1 4.3e-12 45.9 0.1 2.0 1 1 0 1 1 1 1 Beta-lactamase TetR_C_14 PF17754.1 ORY47337.1 - 0.1 12.6 0.6 0.23 11.4 0.2 1.7 1 1 0 2 2 2 0 MftR C-terminal domain DUF3471 PF11954.8 ORY47338.1 - 0.0039 17.6 0.0 0.0065 16.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) tRNA-synt_2e PF02091.15 ORY47338.1 - 0.1 11.8 0.8 0.15 11.3 0.8 1.1 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit Gly_transf_sug PF04488.15 ORY47339.1 - 4.8e-20 72.0 0.0 5.9e-10 39.7 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 ORY47339.1 - 0.0014 18.1 0.0 0.0035 16.8 0.0 1.6 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 ORY47339.1 - 0.0024 17.2 0.0 0.38 10.0 0.0 2.6 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Glyco_trans_1_3 PF13528.6 ORY47340.1 - 3e-09 36.6 0.3 1e-07 31.5 0.2 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.16 ORY47340.1 - 0.00012 22.1 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.6 ORY47340.1 - 0.0041 17.1 0.0 0.0093 16.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 ORY47340.1 - 0.063 13.7 1.8 0.16 12.4 0.0 2.5 3 1 0 3 3 3 0 Glycosyl transferase 4-like domain Gly_transf_sug PF04488.15 ORY47341.1 - 1.3e-05 25.8 0.0 3.5e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif CFTR_R PF14396.6 ORY47341.1 - 0.11 12.0 0.3 0.38 10.3 0.0 1.9 2 0 0 2 2 2 0 Cystic fibrosis TM conductance regulator (CFTR), regulator domain Glyco_tran_28_C PF04101.16 ORY47342.1 - 5.6e-07 29.7 0.0 8.5e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain CBM_5_12_2 PF14600.6 ORY47343.1 - 0.061 13.3 6.4 0.14 12.1 6.4 1.7 1 0 0 1 1 1 0 Cellulose-binding domain UDG PF03167.19 ORY47343.1 - 0.095 12.7 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Uracil DNA glycosylase superfamily Ephrin PF00812.17 ORY47343.1 - 0.45 10.5 4.9 1.3 9.0 0.2 3.2 3 1 0 3 3 3 0 Ephrin Mannosyl_trans3 PF11051.8 ORY47345.1 - 4e-35 121.5 0.1 5.2e-34 117.9 0.1 2.1 1 1 0 1 1 1 1 Mannosyltransferase putative Methyltransf_25 PF13649.6 ORY47346.1 - 1.1e-12 48.5 0.2 5.8e-12 46.2 0.0 2.3 2 1 1 3 3 3 1 Methyltransferase domain PrmA PF06325.13 ORY47346.1 - 4.7e-11 42.6 0.1 1.3e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 ORY47346.1 - 4.4e-10 39.5 0.6 3.6e-09 36.6 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY47346.1 - 1.2e-09 38.6 0.0 3.7e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 ORY47346.1 - 1.2e-06 28.5 0.0 2.3e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY47346.1 - 6.1e-06 25.9 0.1 1.2e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 ORY47346.1 - 3e-05 24.7 0.6 9.4e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain zf-C2H2_2 PF12756.7 ORY47346.1 - 3.3e-05 24.1 0.1 7.8e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Methyltransf_23 PF13489.6 ORY47346.1 - 6.5e-05 22.8 0.0 0.00016 21.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 ORY47346.1 - 0.0025 16.8 0.1 0.0063 15.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_24 PF13578.6 ORY47346.1 - 0.012 16.6 0.1 0.05 14.6 0.0 2.1 2 0 0 2 2 1 0 Methyltransferase domain PRMT5 PF05185.16 ORY47346.1 - 0.014 15.2 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase CMAS PF02353.20 ORY47346.1 - 0.016 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 ORY47346.1 - 0.016 15.3 0.0 0.038 14.1 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase TehB PF03848.14 ORY47346.1 - 0.018 14.5 0.3 0.062 12.7 0.2 2.1 2 1 0 2 2 2 0 Tellurite resistance protein TehB Cons_hypoth95 PF03602.15 ORY47346.1 - 0.041 13.5 0.3 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical protein 95 Methyltransf_32 PF13679.6 ORY47346.1 - 0.045 13.8 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RRM_2 PF04059.12 ORY47347.1 - 9.6e-05 22.5 0.3 0.074 13.3 0.1 2.4 1 1 1 2 2 2 2 RNA recognition motif 2 YjbH PF06082.11 ORY47348.1 - 0.63 8.8 14.1 0.72 8.6 14.1 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH CENP-Q PF13094.6 ORY47348.1 - 4.4 7.5 41.7 0.36 11.0 29.7 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Exonuc_VII_L PF02601.15 ORY47348.1 - 4.7 6.7 20.5 6 6.3 20.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-F_leu_zip PF10473.9 ORY47348.1 - 8.6 6.4 44.9 12 5.9 26.8 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sel1 PF08238.12 ORY47349.1 - 5.9e-30 103.0 20.1 1.8e-09 37.9 1.9 5.1 5 1 0 5 5 5 4 Sel1 repeat TPR_1 PF00515.28 ORY47349.1 - 1.2e-05 25.0 3.8 1.2e-05 25.0 3.8 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORY47349.1 - 1.8e-05 24.4 0.5 1.8e-05 24.4 0.5 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY47349.1 - 1.8e-05 24.9 0.3 1.8e-05 24.9 0.3 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY47349.1 - 1.9e-05 24.4 1.9 1.9e-05 24.4 1.9 4.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY47349.1 - 0.0015 19.2 1.8 0.0015 19.2 1.8 2.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY47349.1 - 0.0017 18.2 5.4 0.18 11.9 0.2 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY47349.1 - 0.0066 16.6 2.3 0.0066 16.6 2.3 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY47349.1 - 0.0086 15.7 2.0 0.0086 15.7 2.0 3.4 4 0 0 4 4 4 1 TPR repeat TPR_6 PF13174.6 ORY47349.1 - 0.057 14.1 9.3 0.21 12.3 0.8 3.9 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF2913 PF11140.8 ORY47349.1 - 0.06 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) SPO22 PF08631.10 ORY47349.1 - 0.2 11.1 4.0 0.25 10.8 1.1 2.0 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like VHS PF00790.19 ORY47350.1 - 1.9e-24 86.1 0.0 8.8e-24 84.0 0.0 2.0 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 ORY47350.1 - 2.8e-24 85.6 2.9 7.6e-24 84.2 2.9 1.8 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 ORY47350.1 - 4.3e-08 33.3 0.1 1.8e-07 31.3 0.1 2.1 2 0 0 2 2 2 1 GAT domain AAA_7 PF12775.7 ORY47350.1 - 0.11 12.0 0.0 0.44 10.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Tubulin PF00091.25 ORY47352.1 - 2.9e-26 92.9 0.5 5.4e-25 88.8 0.1 2.3 1 1 1 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORY47352.1 - 6.7e-09 36.0 1.2 1e-06 29.0 0.2 3.1 1 1 1 2 2 2 2 Tubulin C-terminal domain tRNA_int_end_N2 PF12928.7 ORY47353.1 - 1.9e-05 24.7 0.0 4.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term Fib_alpha PF08702.10 ORY47354.1 - 3.4 7.8 8.3 1.8 8.8 1.0 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Methyltr_RsmB-F PF01189.17 ORY47355.1 - 7.2e-28 97.6 0.0 1.2e-22 80.6 0.0 2.5 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 ORY47355.1 - 2.8e-05 24.0 0.0 0.059 13.2 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 ORY47355.1 - 3.3e-05 23.4 0.0 0.00056 19.3 0.1 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 ORY47355.1 - 0.00011 22.8 0.0 0.0015 19.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY47355.1 - 0.014 16.1 0.0 0.46 11.2 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.19 ORY47355.1 - 0.019 15.1 0.0 0.059 13.5 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_5 PF01795.19 ORY47355.1 - 0.022 14.3 0.0 0.082 12.4 0.0 1.8 2 0 0 2 2 2 0 MraW methylase family MTS PF05175.14 ORY47355.1 - 0.044 13.3 0.1 0.2 11.2 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Pox_MCEL PF03291.16 ORY47355.1 - 0.051 12.7 0.0 0.084 12.0 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme DUF5473 PF17567.2 ORY47356.1 - 0.086 13.1 0.2 0.18 12.1 0.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5473) Robl_LC7 PF03259.17 ORY47357.1 - 8.2e-27 92.8 0.1 9e-27 92.7 0.1 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 ORY47357.1 - 0.00028 20.7 0.0 0.00033 20.5 0.0 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 UPF0176_N PF17773.1 ORY47357.1 - 0.032 14.6 0.0 0.036 14.4 0.0 1.1 1 0 0 1 1 1 0 UPF0176 acylphosphatase like domain RCC1 PF00415.18 ORY47358.1 - 2e-32 111.6 5.9 3.7e-09 37.1 0.0 6.3 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY47358.1 - 9.9e-10 38.0 20.5 0.00033 20.4 0.4 5.6 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat DUF1459 PF07312.11 ORY47358.1 - 0.13 12.5 0.9 42 4.4 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1459) DEAD PF00270.29 ORY47359.1 - 2.3e-19 69.8 0.1 5.5e-19 68.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY47359.1 - 5.5e-19 68.6 0.0 7.2e-16 58.5 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 ORY47359.1 - 6.5e-06 26.3 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RecQ_Zn_bind PF16124.5 ORY47359.1 - 5.6e-05 23.8 0.9 0.00015 22.4 0.9 1.8 1 0 0 1 1 1 1 RecQ zinc-binding AhpC-TSA PF00578.21 ORY47359.1 - 0.11 12.4 0.1 17 5.3 0.0 3.1 3 0 0 3 3 3 0 AhpC/TSA family RBM39linker PF15519.6 ORY47363.1 - 0.24 12.5 2.1 0.8 10.8 0.0 2.3 2 1 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein Sds3 PF08598.11 ORY47364.1 - 2.7e-24 86.4 15.5 4.6e-24 85.7 15.5 1.4 1 1 0 1 1 1 1 Sds3-like Urease_beta PF00699.20 ORY47364.1 - 0.047 13.7 0.0 0.32 11.1 0.0 2.1 2 0 0 2 2 2 0 Urease beta subunit CWC25 PF12542.8 ORY47364.1 - 0.17 12.8 8.7 0.49 11.3 8.7 1.7 1 0 0 1 1 1 0 Pre-mRNA splicing factor Mo25 PF08569.11 ORY47365.1 - 4.1e-139 463.5 4.6 4.7e-139 463.3 4.6 1.0 1 0 0 1 1 1 1 Mo25-like GerE PF00196.19 ORY47365.1 - 0.057 13.0 0.1 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family HEAT_2 PF13646.6 ORY47365.1 - 0.18 12.2 0.0 0.42 11.0 0.0 1.7 1 0 0 1 1 1 0 HEAT repeats Profilin PF00235.19 ORY47366.1 - 5.1e-49 165.8 0.2 5.7e-49 165.6 0.2 1.0 1 0 0 1 1 1 1 Profilin DUF5570 PF17731.1 ORY47366.1 - 0.16 12.0 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5570) LRR_6 PF13516.6 ORY47368.1 - 6.5e-14 50.7 11.2 3.2e-05 23.6 0.0 5.8 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.7 ORY47368.1 - 0.00047 20.5 6.6 0.99 9.9 0.0 4.9 4 1 2 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY47368.1 - 0.0065 16.9 0.1 97 4.1 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 ORY47368.1 - 0.15 11.8 10.9 13 5.7 0.4 4.9 5 2 1 6 6 6 0 Leucine rich repeat Sec66 PF09802.9 ORY47369.1 - 2e-28 99.2 3.6 2e-28 99.2 3.6 1.7 2 0 0 2 2 2 1 Preprotein translocase subunit Sec66 DUF2967 PF11179.8 ORY47369.1 - 0.014 13.6 1.6 0.017 13.3 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) ANAPC_CDC26 PF10471.9 ORY47369.1 - 0.094 13.6 8.9 2.4 9.0 4.1 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 TFIIA PF03153.13 ORY47369.1 - 0.1 12.6 10.3 0.1 12.6 10.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3987 PF13148.6 ORY47369.1 - 0.2 10.6 6.3 0.13 11.2 4.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3987) DUF3138 PF11336.8 ORY47369.1 - 0.72 8.4 4.4 0.91 8.1 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) OmpH PF03938.14 ORY47369.1 - 2 8.7 17.3 0.64 10.3 13.7 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) SUIM_assoc PF16619.5 ORY47369.1 - 2.1 8.5 11.2 6.1 7.0 6.9 2.5 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Amidohydro_3 PF07969.11 ORY47370.1 - 9.5e-14 51.7 10.7 1.7e-07 31.1 0.2 4.0 4 1 0 4 4 4 3 Amidohydrolase family Amidohydro_1 PF01979.20 ORY47370.1 - 2.2e-13 50.3 0.2 5.2e-08 32.6 0.0 3.5 3 1 0 3 3 3 3 Amidohydrolase family DNA_pol_E_B PF04042.16 ORY47371.1 - 1.4e-45 155.2 0.1 2e-45 154.8 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Ank_2 PF12796.7 ORY47373.1 - 1.7e-22 79.7 0.1 2.7e-07 31.1 0.0 4.5 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY47373.1 - 3.7e-13 49.7 1.9 0.16 12.5 0.0 6.9 5 1 2 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY47373.1 - 5.1e-13 49.0 4.8 0.04 14.3 0.0 6.9 4 1 4 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY47373.1 - 5.8e-09 35.5 0.1 7.2 7.5 0.0 8.0 8 0 0 8 8 8 1 Ankyrin repeat Ank PF00023.30 ORY47373.1 - 9.3e-07 29.0 0.4 38 5.0 0.0 7.6 7 1 0 7 7 7 0 Ankyrin repeat DUF5457 PF17540.2 ORY47373.1 - 0.18 11.9 0.0 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5457) Ank_2 PF12796.7 ORY47374.1 - 4.7e-22 78.4 0.8 3.5e-08 33.9 0.0 4.5 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY47374.1 - 1.3e-14 54.4 4.8 0.09 13.4 0.0 6.5 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY47374.1 - 4.2e-09 35.9 3.2 1.9 9.3 0.0 7.9 8 0 0 8 8 8 2 Ankyrin repeat Ank_5 PF13857.6 ORY47374.1 - 4.6e-07 30.0 1.7 3.2 8.2 0.0 6.0 4 2 4 8 8 8 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY47374.1 - 0.00018 21.8 8.3 3.1 8.4 0.0 6.5 7 0 0 7 7 7 2 Ankyrin repeat NTP_transferase PF00483.23 ORY47376.1 - 1.1e-28 100.4 0.0 8.9e-21 74.6 0.0 3.1 1 1 1 2 2 2 2 Nucleotidyl transferase Hexapep PF00132.24 ORY47376.1 - 2.1e-12 46.3 12.6 1e-08 34.6 2.5 4.4 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 ORY47376.1 - 2.4e-07 31.3 0.0 3.6e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 ORY47376.1 - 1.1e-05 25.0 3.4 0.00011 21.8 2.0 3.2 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 ORY47376.1 - 0.048 11.8 0.2 0.08 11.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 ORY47376.1 - 0.1 11.5 0.1 0.36 9.7 0.1 1.9 1 1 0 1 1 1 0 L-fucokinase Amidohydro_1 PF01979.20 ORY47377.1 - 6.4e-53 180.3 0.0 8.9e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY47377.1 - 0.00017 21.2 0.2 0.051 13.0 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 ORY47377.1 - 0.022 14.1 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Adenosine/AMP deaminase TPR_11 PF13414.6 ORY47378.1 - 3.2e-07 29.9 5.8 0.0081 15.8 0.0 4.5 4 0 0 4 4 4 3 TPR repeat TPR_17 PF13431.6 ORY47378.1 - 0.00016 21.8 0.1 0.005 17.1 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TOM20_plant PF06552.12 ORY47378.1 - 0.059 13.1 0.2 0.059 13.1 0.2 2.7 2 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 RAI1 PF08652.11 ORY47379.1 - 0.011 15.9 0.3 0.029 14.6 0.3 1.8 1 1 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease CopG_antitoxin PF12441.8 ORY47379.1 - 0.15 12.6 0.0 0.38 11.3 0.0 1.6 1 0 0 1 1 1 0 CopG antitoxin of type II toxin-antitoxin system tRNA-synt_1c PF00749.21 ORY47380.1 - 6.2e-93 311.1 0.0 7.2e-93 310.9 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain ACPS PF01648.20 ORY47381.1 - 3.4e-13 49.7 0.0 4.2e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Metallophos PF00149.28 ORY47382.1 - 9.8e-14 52.3 0.8 1.4e-13 51.9 0.8 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase vATP-synt_E PF01991.18 ORY47383.1 - 2.4e-62 209.9 13.7 2.8e-62 209.7 13.7 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF826 PF05696.11 ORY47383.1 - 0.067 13.3 0.5 4 7.6 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF826) pXO2-72 PF17443.2 ORY47383.1 - 0.074 13.3 0.7 0.89 9.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein pXO2-72 RNase_T PF00929.24 ORY47383.1 - 0.085 13.4 3.5 0.72 10.4 0.6 2.4 1 1 1 2 2 2 0 Exonuclease RapH_N PF18801.1 ORY47383.1 - 1.3 9.1 8.9 0.16 12.0 1.0 3.3 3 1 0 3 3 3 0 response regulator aspartate phosphatase H, N terminal VCBS PF13517.6 ORY47385.1 - 4.4e-13 49.6 4.3 5.3e-07 30.1 0.4 4.5 3 1 2 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 ORY47385.1 - 0.37 11.0 10.2 4.8 7.4 0.1 4.5 5 0 0 5 5 5 0 FG-GAP repeat 2Fe-2S_thioredx PF01257.19 ORY47386.1 - 1.1e-60 203.7 0.3 1.4e-60 203.4 0.3 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin NIF PF03031.18 ORY47387.1 - 0.00012 21.9 0.0 0.00028 20.7 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase SlyX PF04102.12 ORY47387.1 - 0.16 12.6 0.2 0.81 10.4 0.0 2.1 2 0 0 2 2 2 0 SlyX NIF PF03031.18 ORY47388.1 - 1.5e-05 24.8 0.0 4.2e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase DJ-1_PfpI PF01965.24 ORY47389.1 - 6e-43 146.5 0.1 7.1e-43 146.3 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 ORY47389.1 - 0.00023 20.9 0.8 0.026 14.2 0.1 2.4 1 1 1 2 2 2 2 ThiJ/PfpI family-like GATase PF00117.28 ORY47389.1 - 0.0019 18.0 0.2 0.006 16.4 0.0 1.8 2 1 1 3 3 3 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 ORY47389.1 - 0.026 14.3 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Peptidase C26 PPR_2 PF13041.6 ORY47390.1 - 1.3e-27 95.8 12.4 2.9e-06 27.4 0.0 10.5 7 3 4 11 11 11 5 PPR repeat family PPR_3 PF13812.6 ORY47390.1 - 1.1e-23 83.1 0.6 0.002 18.2 0.0 8.0 8 1 0 8 8 8 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORY47390.1 - 1.9e-14 53.1 3.6 0.0047 16.6 0.0 7.6 8 0 0 8 8 8 4 PPR repeat PPR_long PF17177.4 ORY47390.1 - 4.2e-14 52.4 3.9 0.072 12.4 0.1 6.1 4 1 2 7 7 7 5 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 ORY47390.1 - 1.7e-09 37.3 20.7 0.0014 18.7 0.0 9.1 10 0 0 10 10 10 4 PPR repeat RPM2 PF08579.11 ORY47390.1 - 7.2e-06 26.4 2.4 0.053 13.9 0.3 4.3 2 2 2 4 4 4 2 Mitochondrial ribonuclease P subunit (RPM2) MRP-S27 PF10037.9 ORY47390.1 - 0.00066 18.7 0.1 0.0015 17.5 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S27 Aminotran_1_2 PF00155.21 ORY47391.1 - 2.4e-41 142.1 0.0 3e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ORY47391.1 - 0.0028 16.2 0.0 0.01 14.4 0.0 1.8 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 ORY47391.1 - 0.0049 16.2 0.0 0.0086 15.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 ORY47391.1 - 0.037 12.8 0.0 0.069 11.9 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Aconitase PF00330.20 ORY47392.1 - 2.8e-152 507.9 0.0 3.8e-152 507.5 0.0 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 ORY47392.1 - 1.1e-38 132.5 0.0 2e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 ORY47392.1 - 0.013 14.3 0.0 0.024 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) EF-hand_1 PF00036.32 ORY47393.1 - 1.7e-42 139.8 13.6 2e-10 39.4 1.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORY47393.1 - 3.7e-36 123.4 3.9 1.2e-18 67.4 1.2 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY47393.1 - 4.6e-31 104.1 7.1 1.7e-09 36.8 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 ORY47393.1 - 7e-31 105.9 12.3 1.2e-14 53.8 0.7 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 ORY47393.1 - 1.5e-27 93.8 9.7 1.3e-06 27.6 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 ORY47393.1 - 4.1e-16 59.1 0.2 3.5e-09 36.8 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 ORY47393.1 - 5.2e-10 39.2 1.1 6.1e-05 22.9 0.2 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORY47393.1 - 2.3e-09 37.6 0.1 0.0016 18.8 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 ORY47393.1 - 7.9e-07 29.9 0.0 0.00032 21.5 0.0 2.4 1 1 1 2 2 2 1 EF-hand domain UPF0154 PF03672.13 ORY47393.1 - 2.6e-05 24.2 1.6 0.058 13.4 0.0 3.6 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) Dockerin_1 PF00404.18 ORY47393.1 - 0.00014 22.0 4.4 0.024 14.8 0.4 3.1 1 1 3 4 4 4 1 Dockerin type I domain EFhand_Ca_insen PF08726.10 ORY47393.1 - 0.00021 21.3 1.4 0.00078 19.5 0.2 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand DUF4497 PF14924.6 ORY47393.1 - 0.00035 21.0 0.0 0.72 10.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF4497) Caleosin PF05042.13 ORY47393.1 - 0.002 18.0 1.2 0.62 10.0 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein TerB PF05099.13 ORY47393.1 - 0.0024 17.9 1.3 0.73 9.8 0.0 2.7 1 1 2 3 3 3 1 Tellurite resistance protein TerB DUF3349 PF11829.8 ORY47393.1 - 0.0027 18.5 0.4 3.3 8.6 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) DUF1103 PF06513.11 ORY47393.1 - 0.003 17.2 3.9 0.0036 17.0 3.9 1.2 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Poly_export PF02563.16 ORY47393.1 - 0.0045 17.2 0.1 0.63 10.3 0.0 3.2 1 1 0 2 2 2 1 Polysaccharide biosynthesis/export protein DUF5580 PF17743.1 ORY47393.1 - 0.01 14.4 0.0 0.011 14.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) RNA_pol_Rpb4 PF03874.16 ORY47393.1 - 0.011 16.0 4.3 1.9 8.8 0.1 3.2 3 1 0 3 3 3 0 RNA polymerase Rpb4 MotA_activ PF09114.10 ORY47393.1 - 0.013 15.6 0.4 0.17 12.0 0.1 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain SurA_N_2 PF13623.6 ORY47393.1 - 0.022 14.6 2.0 0.88 9.4 0.1 2.3 1 1 1 2 2 2 0 SurA N-terminal domain dCache_2 PF08269.11 ORY47393.1 - 0.024 13.8 0.3 3.1 6.9 0.1 2.6 1 1 0 2 2 2 0 Cache domain EF-hand_14 PF17959.1 ORY47393.1 - 0.056 13.8 0.2 14 6.1 0.0 2.6 1 1 1 2 2 2 0 EF-hand domain Spore_III_AB PF09548.10 ORY47393.1 - 0.071 13.2 0.9 0.6 10.2 0.9 2.0 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) RloB PF13707.6 ORY47393.1 - 0.14 12.4 1.3 1.9 8.7 1.0 2.2 1 1 0 1 1 1 0 RloB-like protein TetR_C_7 PF14246.6 ORY47393.1 - 0.15 12.1 0.1 8.5 6.4 0.0 2.9 3 1 0 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain RuvA_C PF07499.13 ORY47393.1 - 0.17 12.4 0.1 17 5.9 0.0 3.3 4 0 0 4 4 4 0 RuvA, C-terminal domain SapB_1 PF05184.15 ORY47393.1 - 3.8 7.6 7.3 35 4.5 0.0 4.1 5 0 0 5 5 5 0 Saposin-like type B, region 1 UcrQ PF02939.16 ORY47394.1 - 1.6e-19 69.6 1.1 1.9e-19 69.4 1.1 1.0 1 0 0 1 1 1 1 UcrQ family DUF2002 PF09400.10 ORY47395.1 - 0.15 12.1 0.1 0.36 10.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2002) ABC_tran PF00005.27 ORY47396.1 - 4.7e-53 179.4 0.5 1.6e-30 106.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORY47396.1 - 1.5e-35 123.2 41.5 1.9e-24 86.8 15.7 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ORY47396.1 - 3.1e-14 52.9 2.2 0.00022 20.7 0.2 4.4 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY47396.1 - 1.9e-07 31.2 1.3 0.023 14.8 0.2 3.2 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY47396.1 - 4.6e-07 29.5 7.0 0.007 16.1 0.1 3.5 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_21 PF13304.6 ORY47396.1 - 6.4e-06 26.2 2.0 0.2 11.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORY47396.1 - 7e-06 26.5 0.3 0.049 14.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORY47396.1 - 3.4e-05 23.8 1.6 0.025 14.5 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 ORY47396.1 - 7.6e-05 23.3 8.3 0.18 12.3 0.1 3.5 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 ORY47396.1 - 0.00053 20.1 6.5 0.0051 16.9 0.5 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain NB-ARC PF00931.22 ORY47396.1 - 0.0011 18.2 0.6 0.096 11.9 0.1 2.4 2 0 0 2 2 2 1 NB-ARC domain FtsK_SpoIIIE PF01580.18 ORY47396.1 - 0.0041 16.5 0.9 0.84 8.9 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family ATP_bind_1 PF03029.17 ORY47396.1 - 0.0063 16.3 1.2 0.79 9.5 0.1 2.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Ploopntkinase3 PF18751.1 ORY47396.1 - 0.0068 16.3 1.2 2.9 7.8 0.0 2.7 3 0 0 3 3 2 1 P-loop Nucleotide Kinase3 AAA_22 PF13401.6 ORY47396.1 - 0.01 16.1 6.3 1.3 9.3 0.6 3.4 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 ORY47396.1 - 0.012 15.3 5.0 0.75 9.5 0.8 3.0 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 ORY47396.1 - 0.015 15.9 1.0 6.2 7.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 ORY47396.1 - 0.015 14.3 1.7 0.18 10.8 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Zeta_toxin PF06414.12 ORY47396.1 - 0.017 14.4 1.7 3.7 6.8 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 ORY47396.1 - 0.023 14.3 0.4 1.3 8.6 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORY47396.1 - 0.027 14.0 0.7 5.6 6.4 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Dynamin_N PF00350.23 ORY47396.1 - 0.068 13.2 11.8 0.2 11.7 0.5 3.6 4 0 0 4 4 4 0 Dynamin family cobW PF02492.19 ORY47396.1 - 0.11 12.1 4.6 3.5 7.2 0.7 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.21 ORY47396.1 - 0.12 11.8 0.1 2.7 7.3 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TrwB_AAD_bind PF10412.9 ORY47396.1 - 0.12 11.3 2.3 4.4 6.1 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RNA_helicase PF00910.22 ORY47396.1 - 0.12 12.7 0.2 6 7.3 0.0 2.8 3 0 0 3 3 2 0 RNA helicase DUF815 PF05673.13 ORY47396.1 - 0.19 10.8 0.7 7.2 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Roc PF08477.13 ORY47396.1 - 0.22 11.7 0.9 19 5.5 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 ORY47396.1 - 0.88 9.5 4.7 12 5.8 0.1 3.2 3 0 0 3 3 3 0 NACHT domain SRP54 PF00448.22 ORY47396.1 - 2 8.0 5.7 1.5 8.5 0.1 3.0 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 ORY47396.1 - 2.2 8.5 4.0 20 5.4 0.9 2.5 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 ORY47396.1 - 2.3 7.8 13.8 0.27 10.9 0.4 3.5 4 0 0 4 4 4 0 AAA ATPase domain MeaB PF03308.16 ORY47396.1 - 4.7 6.1 9.1 0.83 8.6 0.1 2.5 3 0 0 3 3 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KH_1 PF00013.29 ORY47397.1 - 8.4e-48 160.1 19.5 1.4e-17 63.3 1.6 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 ORY47397.1 - 4.9e-13 48.7 14.1 9e-05 22.2 0.9 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 ORY47397.1 - 2e-10 40.4 9.4 0.0016 18.3 0.3 3.5 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 ORY47397.1 - 0.00031 20.8 6.9 1.9 8.7 0.1 3.6 3 0 0 3 3 3 3 NusA-like KH domain DUF2067 PF09840.9 ORY47397.1 - 0.045 13.3 0.4 1.1 8.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2067) OpuAC PF04069.12 ORY47398.1 - 6e-16 58.8 5.8 1.2e-08 34.9 1.4 2.3 2 0 0 2 2 2 2 Substrate binding domain of ABC-type glycine betaine transport system Ephrin_rec_like PF07699.13 ORY47398.1 - 0.0019 17.9 5.3 0.0019 17.9 5.3 3.6 3 1 1 4 4 4 1 Putative ephrin-receptor like NCD3G PF07562.14 ORY47398.1 - 0.0099 15.8 1.1 0.0099 15.8 1.1 2.8 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR DMRT-like PF15791.5 ORY47399.1 - 0.14 12.6 0.3 0.14 12.6 0.3 2.1 2 1 0 2 2 2 0 Doublesex-and mab-3-related transcription factor C1 and C2 Myb_DNA-bind_4 PF13837.6 ORY47399.1 - 0.23 11.9 0.0 0.23 11.9 0.0 2.5 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF4407 PF14362.6 ORY47399.1 - 3.5 6.9 8.5 5.4 6.3 8.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DMRT-like PF15791.5 ORY47400.1 - 0.14 12.6 0.3 0.14 12.6 0.3 2.1 2 1 0 2 2 2 0 Doublesex-and mab-3-related transcription factor C1 and C2 Myb_DNA-bind_4 PF13837.6 ORY47400.1 - 0.23 11.9 0.0 0.23 11.9 0.0 2.5 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF4407 PF14362.6 ORY47400.1 - 3.5 6.9 8.5 5.4 6.3 8.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DEAD PF00270.29 ORY47402.1 - 1.5e-17 63.9 0.0 2.4e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ORY47402.1 - 3.4e-05 23.9 0.0 6.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 ORY47402.1 - 0.043 12.5 0.0 0.046 12.4 0.0 1.3 1 1 0 1 1 1 0 SNF2 family N-terminal domain Ly-6_related PF06579.12 ORY47407.1 - 0.15 12.3 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein tRNA-synt_1b PF00579.25 ORY47410.1 - 1.7e-69 234.4 0.0 2.4e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA_bind PF01588.20 ORY47410.1 - 1.5e-30 105.1 0.1 6.5e-30 103.1 0.3 2.0 2 0 0 2 2 2 1 Putative tRNA binding domain DUF4813 PF16072.5 ORY47410.1 - 0.51 10.0 7.1 0.73 9.5 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Synaptobrevin PF00957.21 ORY47411.1 - 1.8e-11 43.7 0.1 3e-11 42.9 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 ORY47411.1 - 2.5e-10 40.2 0.0 5.5e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF782 PF05614.11 ORY47412.1 - 0.039 14.4 0.3 0.078 13.4 0.3 1.5 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF782) DUF3754 PF12576.8 ORY47415.1 - 1.6 8.6 7.8 1.1 9.2 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3754) Colicin_V PF02674.16 ORY47415.1 - 2.6 8.0 16.4 0.017 15.1 4.3 3.0 2 1 1 3 3 3 0 Colicin V production protein DUF3810 PF12725.7 ORY47415.1 - 3.4 6.9 17.5 0.094 12.0 0.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3810) Holin_BhlA PF10960.8 ORY47416.1 - 0.049 13.6 0.5 18 5.4 0.0 3.0 3 0 0 3 3 3 0 BhlA holin family OppC_N PF12911.7 ORY47416.1 - 3.4 7.7 5.9 0.75 9.8 0.6 2.7 3 1 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C PsbN PF02468.15 ORY47416.1 - 5.1 7.0 7.0 1.7 8.5 0.1 3.1 3 0 0 3 3 3 0 Photosystem II reaction centre N protein (psbN) DUF3810 PF12725.7 ORY47417.1 - 4.1 6.6 9.7 0.82 9.0 1.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) Dynein_AAA_lid PF17852.1 ORY47418.1 - 0.013 15.5 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 Dynein heavy chain AAA lid domain Barttin PF15462.6 ORY47418.1 - 0.033 14.0 0.1 0.052 13.3 0.1 1.3 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) DUF3671 PF12420.8 ORY47418.1 - 0.17 11.9 2.4 0.16 12.1 1.2 1.5 1 1 1 2 2 2 0 Protein of unknown function DHHC PF01529.20 ORY47418.1 - 0.24 11.5 6.2 0.64 10.1 5.3 1.8 2 0 0 2 2 2 0 DHHC palmitoyltransferase TFIIA PF03153.13 ORY47419.1 - 0.2 11.6 12.7 0.32 10.9 12.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM76 PF16046.5 ORY47419.1 - 6.1 6.1 9.2 9.8 5.4 9.2 1.3 1 0 0 1 1 1 0 FAM76 protein NACHT PF05729.12 ORY47422.1 - 0.043 13.7 0.0 0.095 12.6 0.0 1.6 1 1 0 1 1 1 0 NACHT domain KNTase_C PF07827.11 ORY47422.1 - 0.071 12.9 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 KNTase C-terminal domain DUF5401 PF17380.2 ORY47423.1 - 4.2 5.3 4.2 5.6 4.9 4.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) LKAAEAR PF15478.6 ORY47424.1 - 0.065 13.5 0.2 0.087 13.1 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function with LKAAEAR motif Pkinase PF00069.25 ORY47427.1 - 7.6e-66 222.2 0.0 8.9e-66 221.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY47427.1 - 5.3e-39 134.1 0.0 6.2e-39 133.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY47427.1 - 2.6e-05 23.7 0.1 0.0015 17.9 0.0 2.3 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 ORY47427.1 - 0.0031 17.5 0.2 0.01 15.8 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Tfb5 PF06331.12 ORY47427.1 - 0.034 14.1 0.5 0.21 11.6 0.2 2.1 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 RIO1 PF01163.22 ORY47427.1 - 0.062 12.9 0.0 0.24 11.0 0.0 1.8 1 1 1 2 2 2 0 RIO1 family Haspin_kinase PF12330.8 ORY47427.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 ORY47427.1 - 0.15 10.8 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase ATP1G1_PLM_MAT8 PF02038.16 ORY47428.1 - 0.15 11.5 0.1 0.29 10.6 0.1 1.4 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Hydrolase_3 PF08282.12 ORY47429.1 - 1.3e-46 159.4 0.0 1.8e-46 159.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 ORY47429.1 - 4.2e-11 42.8 0.0 1.8e-06 27.7 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 ORY47429.1 - 1.3e-06 28.8 0.1 0.00026 21.4 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase 3Beta_HSD PF01073.19 ORY47430.1 - 1.4e-33 116.1 0.0 1.9e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY47430.1 - 9.2e-25 87.5 0.1 1.3e-24 87.0 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY47430.1 - 5e-10 39.3 0.1 1e-09 38.3 0.1 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 ORY47430.1 - 1.7e-09 37.2 2.7 9.7e-09 34.8 0.3 2.1 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 ORY47430.1 - 5.6e-09 36.1 0.0 7.9e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 ORY47430.1 - 0.00037 19.7 1.7 0.0016 17.6 1.7 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 ORY47430.1 - 0.0014 18.6 2.6 0.049 13.5 2.6 2.4 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 ORY47430.1 - 0.0036 16.8 0.3 0.0083 15.6 0.3 1.6 1 1 0 1 1 1 1 short chain dehydrogenase LpxI_N PF17930.1 ORY47430.1 - 0.034 14.0 0.0 0.064 13.2 0.0 1.4 1 0 0 1 1 1 0 LpxI N-terminal domain NmrA PF05368.13 ORY47430.1 - 0.082 12.5 0.2 0.18 11.3 0.2 1.7 1 1 0 1 1 1 0 NmrA-like family FtsJ PF01728.19 ORY47430.1 - 0.15 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase HECT PF00632.25 ORY47431.1 - 9.7e-83 278.2 0.0 1.2e-82 277.9 0.0 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Oxidored_molyb PF00174.19 ORY47431.1 - 0.021 14.4 0.0 0.04 13.5 0.0 1.4 1 1 0 1 1 1 0 Oxidoreductase molybdopterin binding domain Got1 PF04178.12 ORY47432.1 - 1e-17 64.5 9.8 1.3e-17 64.2 9.8 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF308 PF03729.13 ORY47432.1 - 0.72 10.2 11.0 0.19 12.1 7.5 1.8 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) CAAD PF14159.6 ORY47432.1 - 6.5 6.7 7.1 7.9 6.4 0.6 2.5 1 1 1 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase GPCR_chapero_1 PF11904.8 ORY47433.1 - 1.7e-35 122.9 0.0 2.7e-27 96.0 0.0 2.2 2 0 0 2 2 2 2 GPCR-chaperone Ank_2 PF12796.7 ORY47433.1 - 9.9e-07 29.3 0.0 1.8e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY47433.1 - 0.0014 19.0 0.0 4.3 8.2 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 ORY47433.1 - 0.028 15.0 0.0 0.055 14.1 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.30 ORY47433.1 - 0.044 14.2 0.1 2.3 8.8 0.3 2.5 2 0 0 2 2 2 0 Ankyrin repeat M_domain PF12938.7 ORY47434.1 - 0.025 14.4 2.8 0.027 14.3 2.8 1.0 1 0 0 1 1 1 0 M domain of GW182 BUD22 PF09073.10 ORY47437.1 - 0.14 11.5 14.5 0.19 11.0 14.5 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 ORY47437.1 - 1.4 8.3 11.7 2.1 7.7 11.7 1.2 1 0 0 1 1 1 0 SDA1 Rhodanese_C PF12368.8 ORY47439.1 - 0.009 16.4 1.0 0.011 16.1 1.0 1.2 1 0 0 1 1 1 1 Rhodanase C-terminal Mucin PF01456.17 ORY47440.1 - 0.39 10.7 19.6 0.44 10.5 19.6 1.0 1 0 0 1 1 1 0 Mucin-like glycoprotein 2-oxoacid_dh PF00198.23 ORY47441.1 - 4.2e-68 229.3 0.0 6e-68 228.8 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 ORY47441.1 - 4.4e-40 135.4 0.5 1e-18 66.9 0.1 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme E3_binding PF02817.17 ORY47441.1 - 4e-34 116.7 0.3 4.4e-17 62.1 0.1 2.9 2 0 0 2 2 2 2 e3 binding domain Biotin_lipoyl_2 PF13533.6 ORY47441.1 - 5.2e-08 32.6 1.3 0.049 13.5 0.0 4.4 4 0 0 4 4 4 2 Biotin-lipoyl like HlyD_2 PF12700.7 ORY47441.1 - 1.3e-05 24.2 0.6 0.047 12.4 0.1 2.3 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_D23 PF16576.5 ORY47441.1 - 0.00013 21.2 0.3 0.29 10.3 0.0 2.2 2 0 0 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 ORY47441.1 - 0.00025 21.7 0.2 1.5 9.5 0.1 2.7 2 0 0 2 2 2 2 HlyD family secretion protein DUF1948 PF09185.10 ORY47441.1 - 0.017 15.0 0.5 6.2 6.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1948) QRPTase_N PF02749.16 ORY47441.1 - 0.027 14.5 0.1 13 5.9 0.0 3.1 2 2 1 3 3 3 0 Quinolinate phosphoribosyl transferase, N-terminal domain Fve PF09259.11 ORY47441.1 - 0.076 13.2 0.0 13 6.0 0.0 2.6 2 0 0 2 2 2 0 Fungal immunomodulatory protein Fve HTH_Bact PF18768.1 ORY47441.1 - 0.12 11.9 0.0 2.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix bacterial domain Ras PF00071.22 ORY47442.1 - 1.8e-34 118.7 0.2 2.1e-34 118.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY47442.1 - 2.8e-25 88.9 0.3 4.4e-25 88.2 0.1 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY47442.1 - 6.2e-08 32.3 0.1 7.1e-08 32.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY47442.1 - 1.3e-06 27.9 0.2 1.7e-06 27.6 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 ORY47442.1 - 0.00017 20.5 0.1 0.23 10.3 0.0 2.0 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.23 ORY47442.1 - 0.019 15.0 0.0 0.067 13.3 0.0 1.9 1 1 1 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 ORY47442.1 - 0.027 14.2 0.2 0.1 12.3 0.2 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 ORY47442.1 - 0.027 13.6 1.9 0.072 12.2 0.1 2.3 1 1 1 2 2 2 0 G-protein alpha subunit Peptidase_A2E PF12382.8 ORY47442.1 - 0.03 14.3 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 Retrotransposon peptidase SRPRB PF09439.10 ORY47442.1 - 0.03 13.7 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 ORY47442.1 - 0.055 12.9 0.0 1.5 8.2 0.0 2.3 2 1 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 ORY47442.1 - 0.23 11.0 1.4 0.34 10.4 0.1 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region ADK PF00406.22 ORY47443.1 - 8.5e-37 126.6 0.1 9.1e-14 51.8 0.0 3.9 4 0 0 4 4 3 3 Adenylate kinase AAA_17 PF13207.6 ORY47443.1 - 5.8e-24 85.1 2.8 3.9e-09 37.0 0.0 5.2 5 2 1 6 6 5 3 AAA domain FAP206 PF12018.8 ORY47443.1 - 2.6e-18 66.5 0.2 2.5e-06 27.2 0.0 5.3 5 0 0 5 5 5 4 Domain of unknown function YHS PF04945.13 ORY47443.1 - 9e-15 54.5 2.7 0.0067 16.5 0.0 4.6 4 0 0 4 4 4 4 YHS domain Hydin_ADK PF17213.3 ORY47443.1 - 1.2e-08 35.5 2.0 0.0034 17.7 0.0 3.4 4 0 0 4 4 3 2 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 ORY47443.1 - 4.8e-08 33.6 0.1 0.17 12.4 0.0 4.5 3 1 0 3 3 3 2 AAA domain AAA PF00004.29 ORY47443.1 - 4.6e-05 23.9 0.0 9.7 6.6 0.0 4.4 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY47443.1 - 0.0015 18.8 0.0 2.8 8.2 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 ORY47443.1 - 0.0015 18.8 0.0 4.1 7.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 ORY47443.1 - 0.013 15.7 0.0 7.6 6.7 0.0 3.6 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 ORY47443.1 - 0.015 15.8 0.0 0.96 10.0 0.0 2.9 3 0 0 3 3 2 0 ABC transporter AAA_24 PF13479.6 ORY47443.1 - 0.032 13.9 0.5 7.7 6.2 0.0 3.6 4 0 0 4 4 4 0 AAA domain Wbp11 PF09429.10 ORY47443.1 - 0.038 14.4 2.8 0.16 12.4 2.8 2.1 1 0 0 1 1 1 0 WW domain binding protein 11 Dpy-30 PF05186.13 ORY47443.1 - 0.043 13.5 0.1 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 Dpy-30 motif AAA_7 PF12775.7 ORY47443.1 - 0.087 12.3 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP-synt_ab PF00006.25 ORY47443.1 - 0.12 12.0 0.0 5.1 6.7 0.0 2.3 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.23 ORY47443.1 - 0.13 12.3 0.0 8.2 6.6 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 ORY47443.1 - 0.14 12.6 0.2 39 4.7 0.0 3.0 3 0 0 3 3 2 0 RNA helicase CENP-B_dimeris PF09026.10 ORY47443.1 - 1.4 9.3 9.6 0.98 9.9 3.7 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CDC45 PF02724.14 ORY47443.1 - 6.6 4.9 8.2 13 4.0 8.2 1.3 1 0 0 1 1 1 0 CDC45-like protein AAA-ATPase_like PF09820.9 ORY47444.1 - 2.7e-44 151.7 0.2 4.2e-44 151.1 0.2 1.3 1 0 0 1 1 1 1 Predicted AAA-ATPase PDDEXK_9 PF08011.11 ORY47444.1 - 6.1e-07 29.3 0.0 1.6e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily TPR_1 PF00515.28 ORY47445.1 - 2.8e-10 39.5 0.3 1.4e-05 24.7 0.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY47445.1 - 3.3e-09 36.2 0.3 0.0001 22.1 0.6 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY47445.1 - 6.1e-06 26.0 1.0 3.6e-05 23.6 0.3 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY47445.1 - 1.7e-05 24.8 1.8 0.0005 20.3 0.3 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORY47445.1 - 4e-05 23.7 0.1 5.9e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY47445.1 - 4.9e-05 23.9 0.4 8.3e-05 23.2 0.4 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY47445.1 - 0.0014 18.9 0.4 1 9.7 0.4 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY47445.1 - 0.0019 18.9 0.4 0.015 16.1 0.5 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 ORY47445.1 - 0.0036 17.0 0.1 0.014 15.0 0.0 2.0 2 1 0 2 2 2 1 TPR repeat TPR_7 PF13176.6 ORY47445.1 - 0.0057 16.6 0.2 3.6 7.8 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY47445.1 - 0.0083 16.6 3.3 0.055 14.0 0.9 2.9 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY47445.1 - 0.0086 16.6 1.0 0.043 14.4 0.3 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 ORY47445.1 - 0.036 14.5 0.3 0.05 14.0 0.3 1.2 1 0 0 1 1 1 0 Bacterial transcriptional activator domain DUF3106 PF11304.8 ORY47445.1 - 0.11 12.9 3.0 1.5 9.3 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) TPR_10 PF13374.6 ORY47445.1 - 1.7 8.7 4.9 4.7 7.2 0.5 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat RMI2 PF16100.5 ORY47446.1 - 2.5e-07 30.6 0.0 4.3e-07 29.8 0.0 1.4 1 1 0 1 1 1 1 RecQ-mediated genome instability protein 2 dCache_1 PF02743.18 ORY47447.1 - 7e-14 52.2 4.2 1.8e-13 50.9 4.2 1.6 1 1 0 1 1 1 1 Cache domain MRAP PF15183.6 ORY47447.1 - 0.0003 20.7 1.6 0.14 12.1 0.1 2.5 2 0 0 2 2 2 2 Melanocortin-2 receptor accessory protein family DUF5426 PF17473.2 ORY47447.1 - 0.069 13.4 5.1 0.48 10.7 2.3 2.9 2 1 0 2 2 2 0 Family of unknown function (DUF5426) SP_C-Propep PF08999.10 ORY47447.1 - 0.22 11.3 2.3 0.56 10.0 0.2 2.2 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide Baculo_11_kDa PF06143.11 ORY47447.1 - 1.7 8.2 6.9 1.1 8.9 0.8 2.6 2 0 0 2 2 2 0 Baculovirus 11 kDa family Asp PF00026.23 ORY47448.1 - 1.7e-30 106.5 2.4 2.3e-30 106.1 2.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY47448.1 - 1.4e-08 35.1 2.6 1.3e-07 32.0 2.6 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORY47448.1 - 7e-05 23.4 0.8 0.0015 19.2 0.2 3.0 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 ORY47448.1 - 0.082 13.5 0.9 1.9 9.1 0.2 2.8 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease MDM31_MDM32 PF08118.11 ORY47450.1 - 3.2e-118 395.7 0.0 2e-117 393.1 0.0 2.0 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins PAP1 PF08601.10 ORY47450.1 - 0.18 11.5 0.4 0.27 10.9 0.4 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 PIG-U PF06728.13 ORY47451.1 - 7.6e-103 344.5 21.9 8.7e-103 344.3 21.9 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 8TM_micro PF17028.5 ORY47451.1 - 0.19 11.4 17.5 0.015 15.0 12.9 1.5 2 0 0 2 2 2 0 8TM Microsporidial transmembrane domain CPP1-like PF11833.8 ORY47451.1 - 0.2 11.3 0.6 0.53 9.9 0.6 1.7 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like FHA PF00498.26 ORY47452.1 - 1.1e-13 51.3 0.0 2.2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 ORY47452.1 - 4.3e-10 39.2 9.7 8.8e-10 38.2 9.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 ORY47452.1 - 6.1e-09 36.1 12.0 1e-08 35.4 12.0 1.4 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 ORY47452.1 - 0.00059 20.1 0.0 0.0011 19.2 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-ANAPC11 PF12861.7 ORY47452.1 - 0.0013 18.7 5.4 0.0023 17.9 5.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 ORY47452.1 - 0.0028 17.6 12.2 0.0044 16.9 12.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY47452.1 - 0.0055 16.5 10.9 0.0086 15.9 10.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY47452.1 - 0.0068 16.7 8.3 0.014 15.6 8.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORY47452.1 - 0.0069 16.2 13.9 0.012 15.5 13.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 ORY47452.1 - 0.17 11.8 6.1 0.29 11.1 6.1 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 ORY47452.1 - 0.24 11.5 14.7 0.46 10.6 14.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger UBX PF00789.20 ORY47454.1 - 5e-17 61.9 0.1 1e-16 60.9 0.1 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 ORY47454.1 - 8.9e-08 31.8 0.0 2.1e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain Presenilin PF01080.17 ORY47454.1 - 0.057 12.2 1.2 0.11 11.3 1.2 1.4 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 ORY47454.1 - 0.41 9.9 5.1 0.63 9.3 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4449 PF14613.6 ORY47454.1 - 0.89 9.6 7.0 1.6 8.8 7.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) SYS1 PF09801.9 ORY47455.1 - 0.12 12.5 0.2 0.31 11.2 0.1 1.8 2 0 0 2 2 2 0 Integral membrane protein S linking to the trans Golgi network zf-AD PF07776.15 ORY47456.1 - 0.054 13.7 0.1 0.096 12.9 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) MASE4 PF17158.4 ORY47457.1 - 0.066 12.5 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Membrane-associated sensor, integral membrane domain DUF5033 PF16436.5 ORY47457.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5033) Myb_DNA-binding PF00249.31 ORY47458.1 - 0.00059 20.0 0.2 0.54 10.5 0.1 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY47458.1 - 0.17 12.1 1.4 3.2 8.1 0.0 2.7 2 1 1 3 3 3 0 Myb-like DNA-binding domain DEAD PF00270.29 ORY47459.1 - 3.7e-35 121.3 0.4 2e-34 118.9 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY47459.1 - 3e-25 88.7 0.0 3.1e-24 85.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY47459.1 - 8.6e-06 25.8 0.0 0.0025 17.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CDC45 PF02724.14 ORY47459.1 - 0.0045 15.3 7.3 0.0077 14.6 7.3 1.3 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 ORY47459.1 - 0.019 13.2 11.6 0.029 12.6 11.6 1.2 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 ORY47459.1 - 0.028 13.2 3.7 0.044 12.6 3.7 1.2 1 0 0 1 1 1 0 Presenilin LRIF1 PF15741.5 ORY47459.1 - 0.056 12.0 2.5 0.088 11.3 2.5 1.2 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 DUF2457 PF10446.9 ORY47459.1 - 0.062 12.4 17.6 0.094 11.8 17.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Mpp10 PF04006.12 ORY47459.1 - 0.072 11.5 18.0 0.87 8.0 15.2 2.1 2 0 0 2 2 2 0 Mpp10 protein Merozoite_SPAM PF07133.11 ORY47459.1 - 0.1 12.6 17.9 0.22 11.5 17.9 1.5 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DnaI_N PF07319.11 ORY47459.1 - 0.12 13.1 2.0 3.3 8.4 0.3 2.5 2 0 0 2 2 2 0 Primosomal protein DnaI N-terminus TLP-20 PF06088.11 ORY47459.1 - 0.13 12.2 3.3 0.23 11.3 3.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) CobT PF06213.12 ORY47459.1 - 0.19 11.1 15.0 0.34 10.3 15.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RNA_pol_Rpc4 PF05132.14 ORY47459.1 - 0.22 12.0 7.0 0.43 11.0 7.0 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF913 PF06025.12 ORY47459.1 - 0.26 10.2 2.4 0.46 9.4 2.4 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Zip PF02535.22 ORY47459.1 - 0.32 10.2 0.8 0.46 9.6 0.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CPSF100_C PF13299.6 ORY47459.1 - 0.32 11.2 8.7 2.4 8.3 6.5 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 ORY47459.1 - 0.36 10.6 10.1 0.66 9.7 10.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TRAP_alpha PF03896.16 ORY47459.1 - 1.6 7.9 8.7 2.5 7.2 8.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_polI_A34 PF08208.11 ORY47459.1 - 3.2 7.8 19.0 7.4 6.6 19.0 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 FAM176 PF14851.6 ORY47459.1 - 4.9 6.8 8.0 11 5.7 8.0 1.5 1 0 0 1 1 1 0 FAM176 family SURF2 PF05477.11 ORY47459.1 - 8.1 6.1 15.6 14 5.3 15.6 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) PBP_like_2 PF12849.7 ORY47461.1 - 0.0011 18.8 0.1 0.0013 18.5 0.1 1.1 1 0 0 1 1 1 1 PBP superfamily domain LacI PF00356.21 ORY47461.1 - 0.17 11.7 0.2 0.67 9.8 0.1 2.0 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family Glyco_hydro_18 PF00704.28 ORY47464.1 - 1.5e-14 54.5 0.0 2.4e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Neurensin PF14927.6 ORY47467.1 - 2.9 7.6 9.9 82 2.9 9.9 2.3 1 1 0 1 1 1 0 Neurensin FA_desaturase PF00487.24 ORY47467.1 - 3 7.6 4.8 4.5 7.0 4.8 1.4 1 0 0 1 1 1 0 Fatty acid desaturase DUF4212 PF13937.6 ORY47467.1 - 7 7.1 9.6 9.8 6.6 5.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) Polysacc_deac_1 PF01522.21 ORY47468.1 - 2.6e-26 91.9 0.0 3.9e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.21 ORY47470.1 - 1.1e-28 99.7 0.0 1.5e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 ORY47470.1 - 0.11 11.7 0.1 0.61 9.2 0.0 1.8 1 1 1 2 2 2 0 Glycosyl hydrolase family 57 Acetyltransf_1 PF00583.25 ORY47471.1 - 7.4e-11 42.3 0.0 9.4e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY47471.1 - 1.4e-07 31.9 0.0 2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY47471.1 - 5.1e-07 29.7 0.0 6.4e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORY47471.1 - 0.0034 18.0 0.0 0.0044 17.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORY47471.1 - 0.029 14.5 0.0 0.035 14.3 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 ORY47471.1 - 0.035 13.6 0.0 0.057 12.9 0.0 1.4 1 1 0 1 1 1 0 Putative acetyl-transferase FR47 PF08445.10 ORY47471.1 - 0.039 13.9 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.6 ORY47471.1 - 0.14 11.8 0.0 0.18 11.5 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PIG-F PF06699.11 ORY47472.1 - 0.021 15.0 2.9 0.028 14.6 2.9 1.2 1 0 0 1 1 1 0 GPI biosynthesis protein family Pig-F WBS28 PF15164.6 ORY47473.1 - 0.016 14.5 1.1 0.02 14.2 1.1 1.0 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue DUF2663 PF10864.8 ORY47473.1 - 0.14 12.6 1.2 0.22 11.9 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2663) SDF PF00375.18 ORY47475.1 - 1.6e-93 313.9 26.5 1.9e-93 313.6 26.5 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family SDF PF00375.18 ORY47476.1 - 1.7e-82 277.5 29.5 2.1e-82 277.2 29.5 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Cupin_8 PF13621.6 ORY47479.1 - 7.4e-43 147.1 0.2 8.9e-43 146.8 0.2 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 ORY47479.1 - 3e-08 33.5 0.1 4.2e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 ORY47479.1 - 1.9e-07 31.5 0.1 3.2e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 ORY47479.1 - 0.0019 17.8 0.0 0.011 15.5 0.0 2.0 2 0 0 2 2 2 1 Cupin domain ARD PF03079.14 ORY47479.1 - 0.043 14.0 0.0 0.085 13.0 0.0 1.4 1 0 0 1 1 1 0 ARD/ARD' family U79_P34 PF03064.16 ORY47479.1 - 0.18 11.1 0.0 0.25 10.7 0.0 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 GAPES4 PF17157.4 ORY47481.1 - 0.12 12.8 0.1 0.23 11.9 0.1 1.4 1 0 0 1 1 1 0 Gammaproteobacterial periplasmic sensor domain Acetyltransf_4 PF13420.7 ORY47481.1 - 0.13 12.4 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Spore_permease PF03845.13 ORY47482.1 - 0.037 12.9 0.2 0.055 12.3 0.2 1.2 1 0 0 1 1 1 0 Spore germination protein Phage_holin_3_6 PF07332.11 ORY47485.1 - 1.8 8.6 13.7 0.053 13.6 3.0 2.7 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Kei1 PF08552.11 ORY47486.1 - 0.029 14.2 4.3 2.4 8.0 0.2 2.2 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 HSCB_C PF07743.13 ORY47488.1 - 1.8e-15 57.1 4.8 4.2e-15 56.0 0.9 2.1 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 ORY47488.1 - 1.6e-07 31.3 0.5 3.7e-07 30.2 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain DMA PF03474.14 ORY47488.1 - 0.38 10.4 1.2 2.2 7.9 0.0 2.8 2 1 1 3 3 3 0 DMRTA motif RL10P_insert PF17777.1 ORY47489.1 - 7.6e-21 73.9 0.0 1.4e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 ORY47489.1 - 1.2e-11 44.6 0.0 2e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 ABC_membrane PF00664.23 ORY47490.1 - 9.2e-60 202.6 36.0 4.7e-38 131.4 10.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY47490.1 - 1.7e-50 171.1 0.1 5e-28 98.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY47490.1 - 9.7e-09 35.0 7.9 0.013 14.9 0.1 4.2 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY47490.1 - 4.9e-07 29.8 1.7 0.021 14.9 0.2 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 ORY47490.1 - 2.8e-06 27.4 3.3 0.022 14.6 0.0 3.9 3 1 1 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY47490.1 - 3.6e-06 26.6 1.2 0.014 15.1 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 ORY47490.1 - 1.3e-05 24.6 1.0 0.0082 15.5 0.3 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.6 ORY47490.1 - 3.1e-05 24.4 0.1 0.3 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORY47490.1 - 0.00037 20.4 1.5 0.17 11.7 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 ORY47490.1 - 0.00043 19.9 0.3 0.82 9.2 0.1 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 ORY47490.1 - 0.00065 20.0 0.1 0.73 10.1 0.0 2.8 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.17 ORY47490.1 - 0.001 19.2 4.1 0.028 14.5 0.2 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_25 PF13481.6 ORY47490.1 - 0.0037 16.9 0.2 0.28 10.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 ORY47490.1 - 0.0041 17.2 5.3 0.043 13.9 0.4 2.6 2 0 0 2 2 2 1 Dynamin family AAA_15 PF13175.6 ORY47490.1 - 0.014 15.2 0.7 6.4 6.4 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain NACHT PF05729.12 ORY47490.1 - 0.014 15.3 2.6 0.96 9.3 0.0 3.1 3 0 0 3 3 3 0 NACHT domain T2SSE PF00437.20 ORY47490.1 - 0.03 13.4 0.1 6.4 5.7 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.6 ORY47490.1 - 0.03 14.0 0.1 12 5.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ORY47490.1 - 0.036 13.8 0.0 0.71 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ORY47490.1 - 0.037 14.5 4.6 0.88 10.0 0.1 2.8 3 0 0 3 3 3 0 AAA domain Roc PF08477.13 ORY47490.1 - 0.039 14.2 0.2 14 5.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ploopntkinase3 PF18751.1 ORY47490.1 - 0.064 13.2 0.1 10 6.0 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 MobB PF03205.14 ORY47490.1 - 0.073 13.0 0.6 7.6 6.4 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.9 ORY47490.1 - 0.09 11.7 0.3 3.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.19 ORY47490.1 - 0.097 12.3 1.1 1.7 8.2 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Zeta_toxin PF06414.12 ORY47490.1 - 0.11 11.7 0.2 3.3 7.0 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin DUF815 PF05673.13 ORY47490.1 - 0.18 10.9 0.8 12 5.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.17 ORY47490.1 - 0.21 11.3 0.5 17 5.1 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Pox_A32 PF04665.12 ORY47490.1 - 0.37 10.2 1.4 2.5 7.5 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein Exo_endo_phos PF03372.23 ORY47493.1 - 0.01 15.4 0.0 0.044 13.3 0.0 1.9 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family zf-CCHC_4 PF14392.6 ORY47493.1 - 0.13 12.0 0.5 0.28 11.0 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2 PF00096.26 ORY47498.1 - 0.066 13.7 11.0 11 6.6 2.0 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type OrsD PF12013.8 ORY47498.1 - 0.21 12.0 5.8 1.1 9.7 1.8 2.8 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 ORY47498.1 - 6.1 8.0 12.0 28 5.9 2.4 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 ORY47498.1 - 9 6.0 8.7 6.6 6.5 1.3 2.5 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain DUF3450 PF11932.8 ORY47594.1 - 0.00077 18.8 1.2 0.001 18.4 1.0 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) Nsp1_C PF05064.13 ORY47594.1 - 0.00095 19.0 1.0 0.0011 18.8 1.0 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region ZapB PF06005.12 ORY47594.1 - 0.0011 19.4 4.4 0.0014 19.0 4.4 1.3 1 1 0 1 1 1 1 Cell division protein ZapB BLOC1_2 PF10046.9 ORY47594.1 - 0.0022 18.2 0.8 0.0029 17.9 0.8 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 ORY47594.1 - 0.0029 17.5 0.9 0.0033 17.3 0.9 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 BST2 PF16716.5 ORY47594.1 - 0.0042 17.6 2.2 0.0053 17.3 2.2 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 GAS PF13851.6 ORY47594.1 - 0.0057 16.0 2.8 0.0064 15.9 2.8 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding YabA PF06156.13 ORY47594.1 - 0.018 15.6 1.2 0.022 15.4 1.2 1.2 1 0 0 1 1 1 0 Initiation control protein YabA CCDC92 PF14916.6 ORY47594.1 - 0.019 14.7 3.5 0.034 13.9 3.3 1.6 1 1 0 1 1 1 0 Coiled-coil domain of unknown function Cluap1 PF10234.9 ORY47594.1 - 0.019 14.4 1.4 0.02 14.3 1.4 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Herpes_UL6 PF01763.16 ORY47594.1 - 0.019 13.5 1.5 0.02 13.5 1.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like HlyD_D23 PF16576.5 ORY47594.1 - 0.027 13.7 1.0 0.029 13.6 1.0 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion TMF_DNA_bd PF12329.8 ORY47594.1 - 0.034 14.1 1.1 0.034 14.1 1.1 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Rab_bind PF16704.5 ORY47594.1 - 0.034 14.2 0.3 2.8 8.1 0.1 2.3 1 1 1 2 2 2 0 Rab binding domain Sec34 PF04136.15 ORY47594.1 - 0.035 14.0 1.3 0.039 13.8 1.3 1.1 1 0 0 1 1 1 0 Sec34-like family APG6_N PF17675.1 ORY47594.1 - 0.046 14.3 2.7 0.062 13.8 2.7 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF948 PF06103.11 ORY47594.1 - 0.077 13.3 0.4 0.11 12.8 0.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 ORY47594.1 - 0.13 12.5 2.9 0.52 10.5 2.8 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 ORY47594.1 - 0.14 12.4 1.7 0.27 11.5 1.7 1.5 1 0 0 1 1 1 0 Haemolysin XhlA USP8_interact PF08941.10 ORY47594.1 - 0.15 11.9 1.9 0.18 11.6 1.9 1.1 1 0 0 1 1 1 0 USP8 interacting SlyX PF04102.12 ORY47594.1 - 0.27 11.9 4.6 2.1 9.0 4.6 2.1 1 1 0 1 1 1 0 SlyX DivIC PF04977.15 ORY47594.1 - 0.77 9.6 4.7 3.7 7.4 4.7 2.0 1 1 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 ORY47594.1 - 0.98 9.6 3.9 3.9 7.6 1.2 2.3 1 1 1 2 2 2 0 Basic region leucine zipper TniB PF05621.11 ORY47596.1 - 0.18 11.2 0.0 0.62 9.5 0.0 1.7 1 1 1 2 2 2 0 Bacterial TniB protein MFS_1 PF07690.16 ORY47599.1 - 3.4e-28 98.6 24.1 4.6e-28 98.2 24.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ORY47599.1 - 0.02 13.7 15.4 1.1 8.0 6.3 3.1 2 1 1 3 3 3 0 MFS_1 like family TauD PF02668.16 ORY47600.1 - 3e-51 174.8 0.2 3.8e-51 174.5 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Bacillus_PapR PF05968.11 ORY47601.1 - 0.0042 16.9 2.1 0.24 11.3 0.1 3.2 3 0 0 3 3 3 2 Bacillus PapR protein Bacillus_PapR PF05968.11 ORY47602.1 - 0.048 13.5 1.3 4.1 7.3 0.1 2.9 3 0 0 3 3 3 0 Bacillus PapR protein Cpn60_TCP1 PF00118.24 ORY47603.1 - 7.1e-87 292.1 12.5 1.3e-86 291.2 12.5 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cpn10 PF00166.21 ORY47604.1 - 5.1e-28 97.0 0.0 6.3e-28 96.7 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit MazG-like PF12643.7 ORY47606.1 - 2e-18 66.4 0.0 3.5e-09 36.8 0.0 2.3 2 0 0 2 2 2 2 MazG-like family MazG PF03819.17 ORY47606.1 - 7.4e-13 48.5 0.0 5.3e-07 29.7 0.0 2.5 2 0 0 2 2 2 2 MazG nucleotide pyrophosphohydrolase domain Glyco_hydro_114 PF03537.13 ORY47607.1 - 2.8e-32 111.9 0.2 4.2e-32 111.3 0.2 1.2 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Spectrin_like PF18373.1 ORY47607.1 - 0.018 15.1 0.0 0.044 13.9 0.0 1.6 1 0 0 1 1 1 0 Spectrin like domain Pkinase_Tyr PF07714.17 ORY47608.1 - 9.6e-43 146.3 0.0 2.5e-42 145.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 ORY47608.1 - 2.9e-42 144.8 0.0 5.1e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain TPR_1 PF00515.28 ORY47608.1 - 2.2e-39 131.7 15.1 0.00038 20.2 0.0 10.1 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 ORY47608.1 - 1.5e-38 127.8 11.2 5.7e-05 22.9 0.0 10.8 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.6 ORY47608.1 - 1.1e-29 101.9 7.3 4.5e-07 29.4 0.0 8.5 4 3 4 8 8 8 4 TPR repeat TPR_19 PF14559.6 ORY47608.1 - 1.7e-23 82.9 14.1 2.1e-06 28.1 1.0 6.9 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.6 ORY47608.1 - 5.2e-23 79.7 10.0 0.0058 16.9 0.3 8.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 ORY47608.1 - 2.5e-22 79.2 1.8 4.1e-05 24.1 0.0 6.7 7 1 0 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORY47608.1 - 1.8e-21 74.5 15.4 0.0019 18.3 0.0 10.3 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 ORY47608.1 - 1.2e-17 63.9 14.6 2.9e-05 24.3 0.0 8.2 5 2 5 10 10 9 7 Tetratricopeptide repeat TPR_14 PF13428.6 ORY47608.1 - 3.3e-17 61.7 7.9 0.13 13.2 0.1 9.6 6 2 5 11 11 9 6 Tetratricopeptide repeat TPR_9 PF13371.6 ORY47608.1 - 1e-12 48.0 4.9 0.00038 20.5 0.2 5.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY47608.1 - 1.2e-10 40.7 16.7 1 9.5 0.1 9.3 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY47608.1 - 1.5e-08 34.2 7.8 0.11 12.4 0.0 7.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY47608.1 - 3.2e-07 30.1 1.9 0.0038 16.6 0.4 3.8 3 1 0 4 4 4 2 MalT-like TPR region ANAPC3 PF12895.7 ORY47608.1 - 2.3e-06 27.7 14.9 0.059 13.6 0.4 6.4 2 2 4 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.14 ORY47608.1 - 8.2e-06 25.4 1.1 5.5e-05 22.7 1.0 2.1 1 1 0 1 1 1 1 Coatomer epsilon subunit DUF3856 PF12968.7 ORY47608.1 - 1.8e-05 24.9 3.5 0.037 14.1 0.1 4.8 4 1 1 5 5 5 1 Domain of Unknown Function (DUF3856) TPR_4 PF07721.14 ORY47608.1 - 8e-05 22.9 2.6 6.6 7.7 0.1 5.7 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_15 PF13429.6 ORY47608.1 - 0.00018 20.8 3.8 1.7 7.8 0.0 5.3 2 2 2 4 4 4 1 Tetratricopeptide repeat APH PF01636.23 ORY47608.1 - 0.00021 21.3 0.1 0.00062 19.8 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family MIT PF04212.18 ORY47608.1 - 0.0049 16.9 9.4 0.11 12.6 0.0 5.4 6 0 0 6 6 6 1 MIT (microtubule interacting and transport) domain NARP1 PF12569.8 ORY47608.1 - 0.0099 14.8 7.9 0.35 9.7 0.4 3.9 2 1 3 5 5 5 1 NMDA receptor-regulated protein 1 Kinase-like PF14531.6 ORY47608.1 - 0.017 14.4 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like TPR_21 PF09976.9 ORY47608.1 - 0.022 14.4 7.7 4.4 7.0 0.5 4.4 2 1 2 4 4 4 0 Tetratricopeptide repeat-like domain Haspin_kinase PF12330.8 ORY47608.1 - 0.026 13.5 0.0 0.052 12.5 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain BTAD PF03704.17 ORY47608.1 - 0.072 13.5 5.2 21 5.5 0.1 4.3 3 2 0 3 3 3 0 Bacterial transcriptional activator domain ChAPs PF09295.10 ORY47608.1 - 0.11 11.5 2.7 1.2 8.0 0.1 2.8 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Sel1 PF08238.12 ORY47608.1 - 0.15 12.8 2.2 9.7 7.0 0.1 4.5 4 0 0 4 4 2 0 Sel1 repeat DUF728 PF05304.12 ORY47608.1 - 0.19 11.6 0.4 1.5 8.7 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF728) TPR_6 PF13174.6 ORY47608.1 - 0.26 12.0 25.1 3 8.7 0.3 8.4 9 0 0 9 9 7 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 ORY47608.1 - 0.27 10.7 5.0 7.4 6.1 0.0 4.1 4 0 0 4 4 3 0 SHNi-TPR Mad3_BUB1_I PF08311.12 ORY47608.1 - 0.69 9.9 5.6 12 5.9 0.1 3.6 4 0 0 4 4 4 0 Mad3/BUB1 homology region 1 TPR_20 PF14561.6 ORY47608.1 - 2.1 8.7 9.4 9.1 6.7 0.7 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY47609.1 - 1.2e-41 138.8 15.0 0.00057 19.6 0.0 10.3 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 ORY47609.1 - 1.6e-38 127.7 16.3 6.1e-05 22.8 0.0 11.1 12 0 0 12 12 11 9 Tetratricopeptide repeat TPR_11 PF13414.6 ORY47609.1 - 1e-30 105.1 8.2 1.4e-07 31.1 0.0 8.7 4 3 4 8 8 8 4 TPR repeat TPR_17 PF13431.6 ORY47609.1 - 5.3e-24 82.8 11.7 0.0044 17.3 0.3 9.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.6 ORY47609.1 - 7.8e-24 81.9 19.2 0.0033 17.5 0.0 10.9 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 ORY47609.1 - 2.6e-21 75.9 23.0 6.7e-06 26.5 1.0 7.3 5 2 3 8 8 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 ORY47609.1 - 4.3e-19 68.9 16.8 2.3e-05 24.9 0.0 7.9 6 1 2 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 ORY47609.1 - 2.7e-17 62.0 15.8 0.19 12.6 0.0 10.4 5 1 6 11 11 11 5 Tetratricopeptide repeat TPR_12 PF13424.6 ORY47609.1 - 1.6e-16 60.4 16.3 0.0007 19.8 0.0 8.1 4 3 4 8 8 8 6 Tetratricopeptide repeat TPR_9 PF13371.6 ORY47609.1 - 4.6e-13 49.1 10.5 3.4e-05 23.9 0.1 6.3 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY47609.1 - 6.1e-10 38.4 19.1 1.6 8.9 0.0 9.8 12 0 0 12 12 10 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY47609.1 - 5.1e-08 33.0 16.7 0.12 12.6 0.2 6.7 3 3 5 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 ORY47609.1 - 1.1e-06 28.3 3.6 0.0025 17.2 0.5 4.3 3 1 1 4 4 4 1 MalT-like TPR region DUF3856 PF12968.7 ORY47609.1 - 3.6e-05 23.9 2.1 0.019 15.0 0.1 4.6 4 1 0 4 4 4 1 Domain of Unknown Function (DUF3856) TPR_4 PF07721.14 ORY47609.1 - 4.1e-05 23.8 3.4 4.7 8.1 0.1 6.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORY47609.1 - 5.5e-05 22.9 17.7 0.14 12.1 0.0 7.5 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY47609.1 - 0.00049 20.6 20.8 1.9 9.3 0.1 8.0 8 0 0 8 8 8 1 Tetratricopeptide repeat Coatomer_E PF04733.14 ORY47609.1 - 0.00096 18.6 0.2 0.00096 18.6 0.2 3.1 2 1 0 3 3 3 1 Coatomer epsilon subunit SHNi-TPR PF10516.9 ORY47609.1 - 0.0038 16.7 0.0 5.6 6.5 0.0 3.9 3 0 0 3 3 3 1 SHNi-TPR MIT PF04212.18 ORY47609.1 - 0.017 15.2 13.0 0.13 12.4 0.1 5.8 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain Rapsyn_N PF10579.9 ORY47609.1 - 0.037 14.1 0.2 0.34 11.0 0.0 2.8 2 1 1 3 3 2 0 Rapsyn N-terminal myristoylation and linker region ChAPs PF09295.10 ORY47609.1 - 0.077 12.0 4.7 0.63 9.0 0.1 3.0 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) BTAD PF03704.17 ORY47609.1 - 0.15 12.5 6.5 18 5.7 0.1 4.4 4 2 0 4 4 3 0 Bacterial transcriptional activator domain DUF3138 PF11336.8 ORY47609.1 - 0.43 9.2 4.0 0.66 8.5 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Mad3_BUB1_I PF08311.12 ORY47609.1 - 0.5 10.3 6.1 15 5.6 0.3 3.6 4 0 0 4 4 4 0 Mad3/BUB1 homology region 1 DUF728 PF05304.12 ORY47609.1 - 0.73 9.7 2.5 0.98 9.3 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF728) zf-C2H2 PF00096.26 ORY47611.1 - 1.1e-07 31.9 10.0 0.0014 19.0 1.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY47611.1 - 1e-06 29.1 8.2 0.0065 17.2 1.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY47611.1 - 3.9e-05 23.9 1.0 3.9e-05 23.9 1.0 3.4 4 0 0 4 4 4 1 Zinc-finger double domain zf-H2C2_5 PF13909.6 ORY47611.1 - 0.013 15.2 10.6 0.019 14.7 0.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-met PF12874.7 ORY47611.1 - 0.1 13.1 1.1 4.8 7.7 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type CAP_GLY PF01302.25 ORY47611.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 CAP-Gly domain zf-C2H2_jaz PF12171.8 ORY47611.1 - 0.69 10.3 2.2 1.8 8.9 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY47611.1 - 0.85 9.7 4.7 4.8 7.3 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2306 PF10067.9 ORY47612.1 - 2.1e-20 73.4 8.9 3.7e-20 72.6 8.9 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) LRR_8 PF13855.6 ORY47613.1 - 6.1e-11 41.9 48.3 2.3e-05 24.1 9.7 3.4 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY47613.1 - 7.9e-10 38.8 16.5 0.0065 16.9 5.4 4.1 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORY47613.1 - 3e-07 30.2 0.1 7.8e-07 28.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY47613.1 - 0.00023 20.9 0.0 0.00055 19.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.33 ORY47613.1 - 0.0074 16.7 14.9 2.3 9.1 0.3 6.4 6 0 0 6 6 6 1 Leucine Rich Repeat F-box_4 PF15966.5 ORY47613.1 - 0.076 12.9 0.2 0.46 10.4 0.0 2.2 2 0 0 2 2 2 0 F-box MFS_1 PF07690.16 ORY47614.1 - 4.7e-27 94.8 28.0 4.7e-27 94.8 28.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily CAP_GLY PF01302.25 ORY47615.1 - 0.099 12.7 0.4 0.8 9.8 0.1 2.6 3 0 0 3 3 3 0 CAP-Gly domain CAP_N PF01213.19 ORY47616.1 - 0.16 11.4 1.9 0.23 10.9 1.9 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RCDG1 PF15725.5 ORY47616.1 - 1.1 9.7 4.4 2.3 8.7 4.4 1.5 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein TIG_plexin PF17960.1 ORY47617.1 - 0.099 12.7 0.1 0.25 11.4 0.1 1.6 1 1 0 1 1 1 0 TIG domain DUF2225 PF09986.9 ORY47619.1 - 0.15 11.7 0.2 0.24 11.1 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) CAP_GLY PF01302.25 ORY47620.1 - 0.0093 16.0 0.2 0.059 13.4 0.0 2.3 3 0 0 3 3 3 1 CAP-Gly domain EF-hand_6 PF13405.6 ORY47622.1 - 8.5e-19 65.8 15.3 0.016 15.1 0.1 8.5 8 0 0 8 8 8 6 EF-hand domain EF-hand_7 PF13499.6 ORY47622.1 - 1.5e-14 54.2 20.9 0.28 11.7 0.2 8.6 8 0 0 8 8 8 6 EF-hand domain pair EF-hand_8 PF13833.6 ORY47622.1 - 1.1e-10 41.2 1.0 0.098 12.5 0.0 7.3 8 0 0 8 8 8 3 EF-hand domain pair EF-hand_1 PF00036.32 ORY47622.1 - 2.1e-09 36.3 16.1 0.0048 16.3 0.0 8.3 8 0 0 8 8 8 4 EF hand EF-hand_11 PF08976.11 ORY47622.1 - 4.8e-08 33.8 16.2 0.87 10.5 0.1 7.7 8 0 0 8 8 8 3 EF-hand domain DUF5580 PF17743.1 ORY47622.1 - 0.00065 18.4 0.0 0.58 8.6 0.0 3.2 3 1 1 4 4 4 2 Family of unknown function (DUF5580) RST PF12174.8 ORY47622.1 - 0.024 14.5 19.2 0.29 11.1 0.2 6.1 8 0 0 8 8 8 0 RCD1-SRO-TAF4 (RST) plant domain SF3A3 PF16837.5 ORY47622.1 - 0.071 13.6 0.0 1.8 9.1 0.0 3.1 3 0 0 3 3 3 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SelB-wing_3 PF09107.11 ORY47622.1 - 0.084 12.5 0.1 67 3.2 0.0 4.4 5 0 0 5 5 5 0 Elongation factor SelB, winged helix EF-hand_5 PF13202.6 ORY47622.1 - 0.79 9.3 3.1 42 3.9 0.0 4.7 5 0 0 5 5 5 0 EF hand Myb_DNA-bind_6 PF13921.6 ORY47622.1 - 6.4 7.1 5.2 15 5.9 1.2 3.5 3 1 0 3 3 3 0 Myb-like DNA-binding domain Surp PF01805.20 ORY47623.1 - 2e-17 62.9 0.0 5.3e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.22 ORY47623.1 - 5.2e-12 45.4 0.0 3e-11 43.0 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 ORY47623.1 - 0.014 16.2 0.0 0.081 13.8 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase II-binding domain. RRM_7 PF16367.5 ORY47623.1 - 0.049 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif Arm-DNA-bind_4 PF14657.6 ORY47623.1 - 0.059 13.1 1.3 13 5.7 1.5 3.1 2 1 1 3 3 3 0 Arm DNA-binding domain RRM_5 PF13893.6 ORY47623.1 - 0.12 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2306 PF10067.9 ORY47624.1 - 4.8e-11 43.1 3.3 4.8e-11 43.1 3.3 1.7 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) Aldedh PF00171.22 ORY47626.1 - 3.4e-30 105.0 0.0 5.2e-28 97.8 0.0 2.0 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Aldedh PF00171.22 ORY47627.1 - 3e-85 286.5 0.0 3.8e-85 286.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BING4CT PF08149.11 ORY47628.1 - 0.12 12.2 0.0 2.5 8.0 0.0 2.6 3 0 0 3 3 3 0 BING4CT (NUC141) domain PAN_1 PF00024.26 ORY47630.1 - 0.014 15.3 1.3 0.025 14.5 0.2 1.8 2 0 0 2 2 2 0 PAN domain Ank_4 PF13637.6 ORY47631.1 - 0.038 14.6 0.1 0.14 12.8 0.0 1.9 2 1 0 2 2 2 0 Ankyrin repeats (many copies) CAP PF00188.26 ORY47634.1 - 2e-13 51.3 1.4 5.2e-13 49.9 1.4 1.8 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PAN_4 PF14295.6 ORY47634.1 - 3.7e-10 39.6 8.4 9e-05 22.3 0.2 2.8 2 0 0 2 2 2 2 PAN domain PAN_1 PF00024.26 ORY47634.1 - 1.3e-08 34.6 0.1 0.00018 21.4 0.1 2.7 2 0 0 2 2 2 2 PAN domain MANEC PF07502.14 ORY47634.1 - 0.0035 17.6 4.1 1.1 9.5 0.2 3.3 3 0 0 3 3 3 2 MANEC domain PAN_3 PF08277.12 ORY47634.1 - 0.0038 17.0 6.9 0.095 12.5 0.3 2.9 2 0 0 2 2 2 2 PAN-like domain TPR_12 PF13424.6 ORY47635.1 - 6.7e-30 103.2 3.3 1e-11 44.9 0.0 3.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 ORY47635.1 - 3.7e-24 83.8 1.3 2.8e-09 36.5 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY47635.1 - 1.9e-08 33.8 0.6 0.076 13.1 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY47635.1 - 5.4e-08 32.6 2.2 0.00071 19.0 0.0 2.1 1 1 1 2 2 2 2 MalT-like TPR region TPR_8 PF13181.6 ORY47635.1 - 1.9e-07 30.8 0.6 0.15 12.4 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY47635.1 - 2.5e-06 27.2 2.3 0.3 11.3 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY47635.1 - 2.1e-05 25.1 0.2 1 10.1 0.1 4.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORY47635.1 - 4.6e-05 23.9 2.3 0.093 13.6 0.1 4.0 3 1 1 4 4 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY47635.1 - 0.0002 21.5 1.8 6.3 7.1 0.5 4.0 1 1 3 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 ORY47635.1 - 0.00026 21.3 0.3 0.28 11.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY47635.1 - 0.0029 17.4 1.0 0.22 11.4 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 ORY47635.1 - 0.003 17.8 1.0 7.5 7.0 0.2 3.7 1 1 3 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY47635.1 - 0.0083 16.6 0.8 2.9 8.5 0.0 3.7 1 1 2 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY47635.1 - 0.019 15.3 0.7 9.6 6.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat SprA-related PF12118.8 ORY47635.1 - 0.23 10.6 0.3 0.34 10.0 0.3 1.3 1 0 0 1 1 1 0 SprA-related family Cellulase PF00150.18 ORY47636.1 - 7.3e-08 32.2 0.2 1.5e-06 27.9 0.2 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PAN_1 PF00024.26 ORY47638.1 - 2.8e-15 56.0 0.3 1.6e-08 34.3 0.3 2.0 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.6 ORY47638.1 - 3e-07 30.2 4.7 0.004 17.0 0.6 2.3 2 0 0 2 2 2 2 PAN domain PAN_3 PF08277.12 ORY47638.1 - 0.00011 22.0 6.9 0.084 12.7 0.3 2.3 2 0 0 2 2 2 2 PAN-like domain PAN_2 PF08276.11 ORY47638.1 - 0.0004 20.4 4.8 0.084 13.0 0.2 2.2 2 0 0 2 2 2 2 PAN-like domain MANEC PF07502.14 ORY47638.1 - 0.067 13.5 3.3 1.8 8.9 0.6 2.2 2 0 0 2 2 2 0 MANEC domain EPF PF17181.4 ORY47638.1 - 0.12 12.4 4.6 2.9 8.0 0.4 2.2 2 0 0 2 2 2 0 Epidermal patterning factor proteins Toxin_11 PF07473.11 ORY47638.1 - 0.51 10.5 7.9 5.9 7.1 0.9 2.5 2 0 0 2 2 2 0 Spasmodic peptide gm9a; conotoxin from Conus species EMP24_GP25L PF01105.24 ORY47639.1 - 9.9e-42 142.9 0.2 1.5e-41 142.4 0.2 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Haem_bd PF14376.6 ORY47639.1 - 0.038 13.9 0.6 0.53 10.2 0.1 2.1 1 1 1 2 2 2 0 Haem-binding domain Ax_dynein_light PF10211.9 ORY47639.1 - 0.051 13.5 1.5 0.074 13.0 1.5 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain CENP-H PF05837.12 ORY47639.1 - 0.057 13.8 0.9 0.086 13.3 0.9 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Pkinase_Tyr PF07714.17 ORY47640.1 - 1.8e-42 145.4 0.0 3e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORY47640.1 - 8.6e-37 126.9 0.0 1.6e-36 126.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 ORY47640.1 - 0.0013 18.4 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 ORY47640.1 - 0.0053 16.7 1.6 0.01 15.8 0.1 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY47640.1 - 0.0082 15.5 0.3 0.026 13.9 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY47640.1 - 0.021 14.2 0.2 0.065 12.5 0.0 1.9 2 0 0 2 2 2 0 Kinase-like RPW8 PF05659.11 ORY47640.1 - 0.034 13.9 3.2 0.46 10.2 0.4 2.5 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Mei5_like PF17021.5 ORY47640.1 - 0.064 13.3 0.0 0.18 11.9 0.0 1.7 1 1 0 1 1 1 0 Putative double-strand recombination repair-like BofC_C PF08955.10 ORY47641.1 - 0.01 15.8 0.1 0.46 10.6 0.0 2.5 3 0 0 3 3 3 0 BofC C-terminal domain Asp PF00026.23 ORY47646.1 - 3.6e-65 220.4 4.3 4.4e-65 220.2 4.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY47646.1 - 3.5e-13 50.2 0.2 9.4e-11 42.3 0.2 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY47646.1 - 2.2e-05 24.3 0.1 0.0001 22.1 0.1 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 ORY47646.1 - 5.2e-05 23.8 0.1 1.7 9.3 0.0 3.4 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 ORY47646.1 - 0.071 13.7 0.1 25 5.5 0.0 2.8 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Amino_oxidase PF01593.24 ORY47647.1 - 1.2e-50 173.2 0.5 9.8e-50 170.1 0.5 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY47647.1 - 4.1e-09 36.5 0.1 8.3e-09 35.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY47647.1 - 0.0067 16.1 1.4 0.014 15.0 1.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY47647.1 - 0.013 14.8 0.0 0.11 11.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY47647.1 - 0.016 14.5 2.9 0.034 13.4 2.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY47647.1 - 0.019 14.2 1.1 0.029 13.6 0.5 1.5 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 ORY47647.1 - 0.021 13.6 0.6 0.036 12.8 0.6 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 ORY47647.1 - 0.04 14.5 2.4 0.056 14.0 0.9 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY47647.1 - 0.049 12.7 1.8 0.069 12.2 1.8 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 ORY47647.1 - 0.09 12.1 0.6 0.15 11.3 0.6 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 ORY47647.1 - 0.2 10.9 0.4 0.38 9.9 0.4 1.4 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 ORY47647.1 - 0.31 10.3 1.6 0.52 9.6 1.3 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase HNH_2 PF13391.6 ORY47648.1 - 4.1e-10 39.6 0.0 1.2e-09 38.2 0.0 1.8 1 0 0 1 1 1 1 HNH endonuclease HK PF02110.15 ORY47649.1 - 3.5e-66 223.1 13.6 2e-64 217.4 5.7 3.5 3 1 0 3 3 3 2 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 ORY47649.1 - 3.9e-53 179.5 1.5 1e-52 178.1 1.0 1.9 2 0 0 2 2 2 1 Thiamine monophosphate synthase Phos_pyr_kin PF08543.12 ORY47650.1 - 1.9e-92 309.1 1.4 3.4e-92 308.3 1.4 1.4 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 ORY47650.1 - 3.8e-49 167.4 0.3 5.9e-49 166.7 0.3 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 ORY47650.1 - 0.0041 16.5 0.1 0.031 13.6 0.0 2.0 2 0 0 2 2 2 1 pfkB family carbohydrate kinase CbiK PF06180.11 ORY47650.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) DUF900 PF05990.12 ORY47651.1 - 1.9e-05 24.3 0.0 2.9e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF676 PF05057.14 ORY47651.1 - 0.00016 21.2 0.2 0.00047 19.7 0.2 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 ORY47651.1 - 0.011 16.4 0.0 0.014 16.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 ORY47651.1 - 0.021 14.6 0.1 0.032 13.9 0.1 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 ORY47651.1 - 0.045 13.4 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.15 ORY47651.1 - 0.057 12.6 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF4454 PF14628.6 ORY47651.1 - 0.059 13.2 0.0 3.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4454) RRM_1 PF00076.22 ORY47652.1 - 9e-20 70.3 0.1 1.3e-19 69.8 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY47652.1 - 0.012 15.5 0.0 0.02 14.7 0.0 1.3 1 1 0 1 1 1 0 Occluded RNA-recognition motif SET_assoc PF11767.8 ORY47652.1 - 0.093 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated RRM_5 PF13893.6 ORY47652.1 - 0.29 10.8 0.0 0.42 10.2 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) THEG PF14912.6 ORY47653.1 - 0.0066 16.9 0.0 5.4 7.5 0.0 2.3 2 0 0 2 2 2 2 Testicular haploid expressed repeat DEP PF00610.21 ORY47654.1 - 4.5e-18 65.1 0.0 2.8e-12 46.5 0.0 2.5 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RGS PF00615.19 ORY47654.1 - 4.8e-16 59.1 0.0 1.2e-15 57.8 0.0 1.7 1 1 0 1 1 1 1 Regulator of G protein signaling domain Zn_clus PF00172.18 ORY47655.1 - 0.27 11.4 24.5 0.4 10.9 7.6 3.2 2 1 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_2 PF07716.15 ORY47656.1 - 9.4e-10 38.4 3.8 9.4e-10 38.4 3.8 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 ORY47656.1 - 5.8e-08 32.7 3.6 5.8e-08 32.7 3.6 2.2 1 1 2 3 3 3 1 bZIP transcription factor CLZ PF16526.5 ORY47656.1 - 0.0029 17.9 2.4 0.0051 17.2 2.4 1.5 1 1 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Striatin PF08232.12 ORY47656.1 - 0.0038 17.8 0.8 0.0038 17.8 0.8 2.1 1 1 1 2 2 2 1 Striatin family ATG16 PF08614.11 ORY47656.1 - 0.0089 16.3 7.3 0.012 15.8 7.3 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 ORY47656.1 - 0.15 12.1 3.5 0.18 11.9 3.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HAUS-augmin3 PF14932.6 ORY47656.1 - 0.19 11.3 8.1 0.25 10.9 8.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 zinc_ribbon_16 PF17034.5 ORY47657.1 - 0.0087 16.3 0.9 0.01 16.1 0.9 1.2 1 0 0 1 1 1 1 Zinc-ribbon like family DZR PF12773.7 ORY47657.1 - 3 7.9 9.7 3.1e+02 1.5 9.9 2.4 1 1 0 1 1 1 0 Double zinc ribbon JAB PF01398.21 ORY47658.1 - 0.14 12.1 0.2 0.46 10.5 0.1 1.9 2 0 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Zn_clus PF00172.18 ORY47660.1 - 0.0045 17.1 4.7 0.0045 17.1 4.7 2.9 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 ORY47661.1 - 0.0097 16.0 9.6 0.014 15.5 9.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PI3Ka PF00613.20 ORY47662.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) COG5 PF10392.9 ORY47662.1 - 0.038 14.2 0.2 0.087 13.0 0.2 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 FlaC_arch PF05377.11 ORY47662.1 - 0.054 13.9 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) THUMP PF02926.17 ORY47662.1 - 0.17 12.0 0.2 0.3 11.2 0.2 1.3 1 0 0 1 1 1 0 THUMP domain DUF3716 PF12511.8 ORY47662.1 - 0.61 10.2 5.3 1.1 9.3 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Zn_clus PF00172.18 ORY47662.1 - 2 8.6 9.3 5.6 7.2 9.3 1.8 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrom_B561 PF03188.16 ORY47664.1 - 2.5e-16 60.0 4.9 4.4e-16 59.3 4.9 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF4079 PF13301.6 ORY47664.1 - 0.0013 18.9 3.3 0.0049 17.0 3.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4079) DUF1345 PF07077.11 ORY47664.1 - 0.0088 15.8 3.1 0.012 15.4 1.9 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1345) Ni_hydr_CYTB PF01292.20 ORY47664.1 - 0.018 14.7 9.7 0.12 12.0 7.8 2.6 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF2231 PF09990.9 ORY47664.1 - 0.027 14.9 5.4 0.036 14.5 4.0 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2231) DUF423 PF04241.15 ORY47664.1 - 0.096 12.9 5.0 0.098 12.9 0.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF423) DUF2371 PF10177.9 ORY47664.1 - 0.13 12.4 0.7 1.2 9.3 0.0 2.7 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2371) DUF2207 PF09972.9 ORY47664.1 - 0.22 10.2 2.5 0.65 8.7 2.4 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) PepSY_TM PF03929.16 ORY47664.1 - 0.27 10.9 10.3 0.017 14.8 3.5 2.4 2 1 0 3 3 3 0 PepSY-associated TM region MMR_HSR1 PF01926.23 ORY47666.1 - 1.5e-17 63.7 0.0 1.9e-13 50.5 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY47666.1 - 2e-10 40.4 0.1 3.4e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ORY47666.1 - 6e-06 26.3 0.2 0.065 13.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 ORY47666.1 - 0.00011 21.8 0.2 0.0044 16.6 0.0 2.7 1 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 ORY47666.1 - 0.00064 19.8 0.7 0.021 14.9 0.4 2.7 2 1 0 2 2 2 1 Dynamin family AIG1 PF04548.16 ORY47666.1 - 0.0019 17.6 0.2 0.0064 15.9 0.1 1.8 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 ORY47666.1 - 0.023 14.9 0.1 12 6.1 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 ORY47666.1 - 0.042 13.4 0.1 1.5 8.4 0.0 2.5 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NOG1 PF06858.14 ORY47666.1 - 0.081 12.7 0.0 4.2 7.2 0.0 3.1 3 0 0 3 3 3 0 Nucleolar GTP-binding protein 1 (NOG1) AAA_18 PF13238.6 ORY47666.1 - 0.11 13.0 0.2 0.33 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 ORY47666.1 - 0.14 11.9 0.0 0.52 10.1 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF5092 PF17010.5 ORY47667.1 - 1.6e-27 96.4 1.1 1.2e-26 93.5 1.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF5092) Ferlin_C PF16165.5 ORY47667.1 - 0.031 14.2 0.6 0.075 13.0 0.6 1.5 1 0 0 1 1 1 0 Ferlin C-terminus Vps52 PF04129.12 ORY47668.1 - 0.057 12.2 2.1 0.035 12.9 0.7 1.3 2 0 0 2 2 2 0 Vps52 / Sac2 family Spc7 PF08317.11 ORY47668.1 - 0.074 11.9 0.7 6.2 5.6 0.1 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Thg1 PF04446.12 ORY47669.1 - 4.3e-50 168.9 0.2 7e-50 168.3 0.2 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 ORY47669.1 - 4.7e-41 139.8 1.0 1.2e-40 138.5 1.0 1.7 1 1 0 1 1 1 1 Thg1 C terminal domain KH_9 PF17904.1 ORY47669.1 - 0.052 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 FMRP KH0 domain Prok-RING_1 PF14446.6 ORY47670.1 - 0.0006 19.7 1.6 0.0013 18.7 1.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 DUF35_N PF12172.8 ORY47670.1 - 0.022 14.7 0.2 4.3 7.3 0.1 2.6 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) TF_Zn_Ribbon PF08271.12 ORY47670.1 - 0.12 11.9 1.1 0.21 11.1 1.1 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding A2L_zn_ribbon PF08792.10 ORY47670.1 - 0.14 12.0 1.5 0.27 11.0 1.5 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain PHD PF00628.29 ORY47670.1 - 0.17 11.8 2.1 0.2 11.6 0.8 1.8 2 0 0 2 2 2 0 PHD-finger Nudix_N_2 PF14803.6 ORY47670.1 - 0.23 11.4 1.4 0.57 10.1 0.6 2.1 2 0 0 2 2 2 0 Nudix N-terminal CDK2AP PF09806.9 ORY47670.1 - 0.55 10.3 6.6 0.72 9.9 6.5 1.3 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF4962 PF16332.5 ORY47671.1 - 9.7e-16 57.3 2.8 1.2e-15 57.0 0.3 2.1 2 1 1 3 3 3 1 Domain of unknown function (DUF4962) Hepar_II_III PF07940.13 ORY47671.1 - 1.1e-12 48.0 2.0 2.9e-12 46.7 1.7 1.6 1 1 0 1 1 1 1 Heparinase II/III-like protein TPR_12 PF13424.6 ORY47671.1 - 0.15 12.3 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat WD40 PF00400.32 ORY47672.1 - 5.2e-32 109.4 25.1 0.00015 22.5 0.1 12.0 12 0 0 12 12 12 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY47672.1 - 4.9e-10 39.6 0.0 0.0026 18.0 0.0 5.6 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY47672.1 - 0.006 15.3 0.1 1.1 7.8 0.0 3.9 5 1 0 5 5 5 1 Nucleoporin Nup120/160 Nbas_N PF15492.6 ORY47672.1 - 0.067 12.5 0.0 0.86 8.9 0.0 2.6 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal CENP-B_N PF04218.13 ORY47673.1 - 0.0097 15.5 0.7 0.017 14.8 0.7 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 ORY47673.1 - 0.046 14.0 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 Transposase Zn_clus PF00172.18 ORY47675.1 - 0.0035 17.4 12.9 0.0055 16.8 12.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_1 PF00515.28 ORY47676.1 - 4e-21 73.9 0.2 2.6e-09 36.5 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY47676.1 - 1.1e-17 62.6 0.1 6.9e-08 32.0 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY47676.1 - 1.8e-14 53.1 0.2 8e-10 38.2 0.4 3.1 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 ORY47676.1 - 7.2e-14 50.8 0.3 3.2e-06 26.9 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY47676.1 - 5e-10 39.9 0.0 0.00017 22.2 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY47676.1 - 2.1e-09 37.4 0.0 0.00012 22.2 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY47676.1 - 9.9e-09 35.6 0.1 3.3e-08 33.9 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY47676.1 - 2.3e-08 34.2 0.0 0.024 15.4 0.0 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORY47676.1 - 2.6e-08 33.7 0.4 7.9e-05 22.8 0.2 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY47676.1 - 2.3e-07 30.3 0.0 0.035 14.1 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY47676.1 - 1.9e-06 27.8 0.7 0.15 12.1 0.0 3.4 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 ORY47676.1 - 5.2e-06 26.7 0.0 1.9e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY47676.1 - 0.00011 22.6 0.1 0.21 12.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY47676.1 - 0.0026 18.0 0.2 0.0056 16.9 0.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 ORY47676.1 - 0.018 14.8 2.3 0.19 11.4 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 ORY47676.1 - 0.024 14.5 0.0 3 7.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 ORY47676.1 - 0.033 14.2 0.8 0.064 13.3 0.8 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat RPN7 PF10602.9 ORY47677.1 - 4.8e-36 124.1 0.0 8.6e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 ORY47677.1 - 1.5e-13 51.1 0.0 2.7e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 ORY47677.1 - 0.00087 19.2 0.0 1.1 9.5 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY47677.1 - 0.033 14.0 0.1 4.5 7.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Vps55 PF04133.14 ORY47678.1 - 3.9e-40 136.4 7.6 4.4e-40 136.3 7.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 LtrA PF06772.11 ORY47678.1 - 0.018 14.2 1.0 0.018 14.2 1.0 1.9 2 0 0 2 2 2 0 Bacterial low temperature requirement A protein (LtrA) SpoIIIAC PF06686.11 ORY47678.1 - 0.074 13.2 1.8 0.074 13.2 1.8 2.3 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family NEMP PF10225.9 ORY47678.1 - 2 8.0 7.9 1.5 8.4 3.5 2.0 2 0 0 2 2 2 0 NEMP family HDAC4_Gln PF12203.8 ORY47679.1 - 0.062 13.5 0.5 0.14 12.3 0.5 1.5 1 0 0 1 1 1 0 Glutamine rich N terminal domain of histone deacetylase 4 Tenui_NCP PF04876.12 ORY47679.1 - 0.13 11.9 0.2 1.1 8.8 0.1 2.1 2 0 0 2 2 2 0 Tenuivirus major non-capsid protein DUF3361 PF11841.8 ORY47680.1 - 7.3e-05 22.7 9.0 0.00026 21.0 3.5 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3361) THF_DHG_CYH PF00763.23 ORY47680.1 - 0.084 13.1 0.1 0.19 12.0 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain adh_short PF00106.25 ORY47681.1 - 9.4e-40 136.2 0.0 1.2e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY47681.1 - 2.4e-26 92.8 0.0 2.8e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY47681.1 - 5.1e-06 26.5 0.0 6.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF5311 PF17238.2 ORY47681.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5311) Phtf-FEM1B_bdg PF12129.8 ORY47682.1 - 0.13 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor TPR_12 PF13424.6 ORY47683.1 - 8.6e-13 48.4 9.1 1.4e-06 28.5 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY47683.1 - 3e-12 45.7 6.6 0.011 15.8 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY47683.1 - 4.8e-12 45.0 7.0 0.046 13.9 0.5 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 ORY47683.1 - 1.4e-11 43.7 8.3 0.039 13.8 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY47683.1 - 1.1e-08 34.6 14.5 0.013 15.7 0.4 6.1 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 ORY47683.1 - 2.1e-08 34.3 9.3 0.65 10.8 0.2 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY47683.1 - 6.3e-07 29.9 1.7 0.091 13.4 0.1 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY47683.1 - 5.4e-06 26.0 0.1 0.00039 19.9 0.0 2.6 2 2 0 2 2 2 1 MalT-like TPR region TPR_14 PF13428.6 ORY47683.1 - 3.5e-05 24.3 9.1 0.74 10.8 0.0 6.9 8 1 1 9 9 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY47683.1 - 0.00016 21.8 9.5 0.01 16.0 1.0 4.1 2 2 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 ORY47683.1 - 0.00094 19.4 2.2 0.4 11.2 0.1 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORY47683.1 - 0.0067 16.3 1.8 62 3.7 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 ORY47683.1 - 0.0083 15.4 0.1 0.26 10.5 0.0 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat RPN7 PF10602.9 ORY47683.1 - 0.013 15.2 0.3 0.013 15.2 0.3 2.1 2 1 0 2 2 2 0 26S proteasome subunit RPN7 RIP PF00161.19 ORY47683.1 - 0.05 13.2 0.2 7.3 6.1 0.1 2.3 1 1 1 2 2 2 0 Ribosome inactivating protein TPR_19 PF14559.6 ORY47683.1 - 0.14 12.6 9.3 2.5 8.7 0.1 4.0 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY47683.1 - 0.27 10.9 5.4 18 5.1 0.0 5.0 5 1 1 6 6 6 0 TPR repeat DNA_pol_phi PF04931.13 ORY47684.1 - 2.2 6.3 7.7 2.2 6.3 7.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi Spt5_N PF11942.8 ORY47684.1 - 2.5 9.1 11.4 3.6 8.6 11.4 1.3 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal RRN3 PF05327.11 ORY47684.1 - 8.7 4.8 6.3 9.9 4.6 6.3 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Par3_HAL_N_term PF12053.8 ORY47685.1 - 0.00018 21.7 0.8 0.00026 21.1 0.8 1.3 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins CENP-L PF13092.6 ORY47686.1 - 1.7e-05 25.1 0.1 5.3e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Kinetochore complex Sim4 subunit Fta1 RPE65 PF03055.15 ORY47687.1 - 2e-56 192.1 0.1 2.3e-56 191.9 0.1 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RPE65 PF03055.15 ORY47688.1 - 8.3e-21 74.7 0.0 9.9e-21 74.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein RPE65 PF03055.15 ORY47689.1 - 1.7e-88 297.9 0.0 2.3e-88 297.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Coq4 PF05019.13 ORY47690.1 - 1.3e-77 260.1 0.0 1.4e-77 259.9 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Oxysterol_BP PF01237.18 ORY47691.1 - 2.8e-128 427.9 0.0 5.1e-128 427.1 0.0 1.4 1 1 0 1 1 1 1 Oxysterol-binding protein GOLD_2 PF13897.6 ORY47692.1 - 3.7e-08 34.0 0.0 0.00043 20.8 0.0 2.2 1 1 1 2 2 2 2 Golgi-dynamics membrane-trafficking PH_8 PF15409.6 ORY47692.1 - 2.6e-05 24.4 0.0 5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 ORY47692.1 - 0.00014 22.3 0.0 0.0005 20.5 0.0 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 ORY47692.1 - 0.049 14.1 0.0 0.1 13.0 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Sulfate_transp PF00916.20 ORY47693.1 - 2.8e-92 309.4 23.0 3.7e-92 309.0 23.0 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORY47693.1 - 5.8e-11 42.1 0.0 1.3e-10 40.9 0.0 1.5 1 1 0 1 1 1 1 STAS domain STAS_2 PF13466.6 ORY47693.1 - 0.00051 20.3 0.1 0.001 19.4 0.1 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ORY47693.1 - 0.014 15.8 2.6 0.014 15.8 2.6 2.8 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily CAP PF00188.26 ORY47694.1 - 3e-16 60.4 0.7 3.8e-16 60.1 0.7 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family HORMA PF02301.18 ORY47695.1 - 6.2e-27 94.6 1.6 7.2e-27 94.4 1.6 1.0 1 0 0 1 1 1 1 HORMA domain dCMP_cyt_deam_1 PF00383.23 ORY47695.1 - 0.024 14.5 0.3 0.047 13.6 0.3 1.4 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region Herpes_BLRF2 PF05812.12 ORY47695.1 - 0.029 14.5 0.7 0.098 12.8 0.2 1.9 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein bacHORMA_2 PF18173.1 ORY47695.1 - 0.076 12.9 0.3 0.24 11.2 0.1 1.9 2 1 0 2 2 2 0 Bacterial HORMA domain 2 Arcadin_1 PF18653.1 ORY47695.1 - 0.091 12.8 0.8 1.9 8.6 0.1 2.2 2 0 0 2 2 2 0 Arcadin 1 Membr_traf_MHD PF10540.9 ORY47695.1 - 0.26 11.5 4.4 0.34 11.1 4.0 1.3 1 1 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain FixO PF02433.15 ORY47695.1 - 0.32 10.4 4.7 6.5 6.1 0.1 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO Leu_zip PF15294.6 ORY47695.1 - 2.4 7.6 9.8 0.059 12.9 2.3 1.9 2 1 1 3 3 3 0 Leucine zipper Hemolysin_N PF12563.8 ORY47696.1 - 0.015 14.9 0.0 0.04 13.5 0.0 1.6 1 0 0 1 1 1 0 Hemolytic toxin N terminal Syja_N PF02383.18 ORY47698.1 - 4.8e-87 292.3 0.1 6e-87 291.9 0.1 1.1 1 0 0 1 1 1 1 SacI homology domain MFS_1 PF07690.16 ORY47699.1 - 3.7e-11 42.6 29.1 1.4e-08 34.1 19.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 ORY47699.1 - 3.2e-06 26.9 5.1 3.2e-06 26.9 5.1 2.9 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 Acetyltransf_1 PF00583.25 ORY47700.1 - 8.8e-15 55.0 0.0 1.3e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY47700.1 - 4.3e-10 39.6 0.0 7.1e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY47700.1 - 1.4e-08 35.1 0.0 2.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORY47700.1 - 0.0013 18.9 0.3 0.0078 16.4 0.3 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORY47700.1 - 0.0067 17.1 0.2 0.0084 16.8 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PTS_EIIA_1 PF00358.20 ORY47700.1 - 0.015 15.1 0.0 0.038 13.8 0.0 1.6 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 FR47 PF08445.10 ORY47700.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein SCO1-SenC PF02630.14 ORY47701.1 - 6.7e-46 155.5 0.0 8.8e-46 155.2 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 ORY47701.1 - 2.6e-06 27.4 0.0 6.6e-06 26.0 0.0 1.8 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.6 ORY47701.1 - 1.1e-05 25.6 0.0 1.8e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 ORY47701.1 - 0.023 14.4 0.0 0.064 13.0 0.0 1.7 1 1 0 1 1 1 0 Redoxin IL10 PF00726.17 ORY47701.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Interleukin 10 dCache_1 PF02743.18 ORY47701.1 - 0.15 11.8 0.0 3.8 7.2 0.1 2.5 2 1 1 3 3 3 0 Cache domain MT-A70 PF05063.14 ORY47703.1 - 2.1e-26 92.9 0.0 2.3e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 MT-A70 FA_desaturase PF00487.24 ORY47704.1 - 4.6e-15 56.2 24.4 6.8e-15 55.6 24.4 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 ORY47704.1 - 1e-14 54.4 0.0 2.1e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 ORY47705.1 - 2.8e-17 63.4 19.3 3.8e-17 63.0 19.3 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 ORY47705.1 - 2.5e-14 53.2 0.0 6e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2439 PF10382.9 ORY47706.1 - 2.3e-08 34.2 0.0 5.4e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) PIF1 PF05970.14 ORY47706.1 - 0.0017 17.6 0.1 0.0026 17.0 0.1 1.2 1 0 0 1 1 1 1 PIF1-like helicase Kinesin PF00225.23 ORY47706.1 - 0.015 14.3 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinesin motor domain AAA_30 PF13604.6 ORY47706.1 - 0.088 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2791 PF10923.8 ORY47706.1 - 0.12 11.2 0.1 0.19 10.5 0.1 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) Dicty_REP PF05086.12 ORY47706.1 - 0.45 8.4 3.0 0.69 7.8 3.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein IF-2B PF01008.17 ORY47707.1 - 5.6e-69 232.5 0.6 6.5e-69 232.2 0.6 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF4440 PF14534.6 ORY47707.1 - 0.082 13.3 0.0 22 5.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) UPF0184 PF03670.13 ORY47707.1 - 0.15 12.4 0.8 0.29 11.5 0.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Proteasome PF00227.26 ORY47708.1 - 3e-51 173.6 0.2 5.4e-51 172.8 0.1 1.4 2 0 0 2 2 2 1 Proteasome subunit Pr_beta_C PF12465.8 ORY47708.1 - 7.1e-09 34.9 0.0 7.1e-09 34.9 0.0 2.1 2 0 0 2 2 2 1 Proteasome beta subunits C terminal GIY-YIG PF01541.24 ORY47709.1 - 1.6e-14 53.9 0.0 2.7e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 GIY-YIG catalytic domain PHD_Oberon PF07227.11 ORY47709.1 - 0.0014 18.5 0.8 0.0022 17.9 0.8 1.2 1 0 0 1 1 1 1 PHD - plant homeodomain finger protein PHD PF00628.29 ORY47709.1 - 0.016 15.1 2.5 0.025 14.5 1.4 2.0 1 1 1 2 2 2 0 PHD-finger C1_1 PF00130.22 ORY47709.1 - 0.19 11.7 2.2 0.31 11.0 0.2 2.1 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 ORY47709.1 - 0.45 10.9 3.3 0.27 11.6 0.4 2.0 2 0 0 2 2 2 0 C1 domain zf-RING_2 PF13639.6 ORY47709.1 - 6.9 7.1 8.2 6.8 7.1 5.5 2.3 1 1 1 2 2 2 0 Ring finger domain zf-MYND PF01753.18 ORY47710.1 - 3e-10 40.0 6.4 3e-10 40.0 6.4 2.1 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 ORY47710.1 - 0.12 12.7 4.4 0.31 11.4 4.4 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Lipoprotein_3 PF00938.17 ORY47710.1 - 0.13 12.4 0.0 0.36 11.0 0.0 1.7 1 0 0 1 1 1 0 Lipoprotein zf-MYND PF01753.18 ORY47711.1 - 1.3e-10 41.2 12.3 1.3e-10 41.2 12.3 2.2 2 0 0 2 2 2 1 MYND finger TPR_12 PF13424.6 ORY47711.1 - 0.038 14.3 0.1 2.2 8.6 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C6H2 PF15801.5 ORY47711.1 - 1 9.7 15.1 0.21 11.9 10.9 2.0 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding PolC_DP2 PF03833.13 ORY47711.1 - 1.9 6.2 5.7 2.8 5.7 5.7 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-HIT PF04438.16 ORY47711.1 - 5.7 6.9 8.3 15 5.5 8.3 1.8 1 0 0 1 1 1 0 HIT zinc finger cNMP_binding PF00027.29 ORY47712.1 - 4.6e-12 45.8 0.0 1.4e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 ORY47712.1 - 2.1e-05 23.9 20.0 3.6e-05 23.1 20.0 1.3 1 0 0 1 1 1 1 Ion transport protein Sec62 PF03839.16 ORY47713.1 - 1.7e-49 168.3 7.7 7.5e-48 162.9 7.7 2.0 1 1 0 1 1 1 1 Translocation protein Sec62 DEP PF00610.21 ORY47713.1 - 0.0031 17.5 0.0 0.0058 16.7 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Peptidase_U4 PF03419.13 ORY47713.1 - 6.3 6.0 6.1 10 5.3 6.1 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA CHCH PF06747.13 ORY47714.1 - 1.4e-06 28.3 4.4 4.4e-06 26.7 4.4 2.0 1 0 0 1 1 1 1 CHCH domain BUD22 PF09073.10 ORY47714.1 - 0.0037 16.7 17.4 0.0048 16.3 17.4 1.1 1 0 0 1 1 1 1 BUD22 DUF4667 PF15700.5 ORY47714.1 - 0.025 14.7 2.7 0.037 14.1 2.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4667) Presenilin PF01080.17 ORY47714.1 - 1.2 7.8 6.4 1.6 7.4 6.4 1.2 1 0 0 1 1 1 0 Presenilin PPP4R2 PF09184.11 ORY47714.1 - 4.4 6.8 22.8 6.6 6.2 22.8 1.4 1 1 0 1 1 1 0 PPP4R2 RNA_pol_Rpc4 PF05132.14 ORY47714.1 - 9.1 6.7 10.7 6.4 7.2 0.6 2.1 2 0 0 2 2 2 0 RNA polymerase III RPC4 ETC_C1_NDUFA5 PF04716.14 ORY47717.1 - 4.8e-13 48.7 0.0 6.6e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region TIMELESS PF04821.14 ORY47718.1 - 1.6e-51 175.3 2.5 4.4e-43 147.5 1.3 3.0 1 1 1 2 2 2 2 Timeless protein TIMELESS_C PF05029.13 ORY47718.1 - 7.3e-09 35.3 1.5 7.3e-09 35.3 1.5 3.4 2 1 0 2 2 2 1 Timeless protein C terminal region DTHCT PF08070.11 ORY47718.1 - 0.95 10.2 27.4 0.37 11.5 11.5 3.4 2 1 0 2 2 2 0 DTHCT (NUC029) region Bacillus_PapR PF05968.11 ORY47720.1 - 4.8 7.1 6.3 2.7 7.9 0.1 3.4 5 0 0 5 5 5 0 Bacillus PapR protein NAPRTase PF04095.16 ORY47722.1 - 4.4e-40 137.8 0.0 6.6e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF5598 PF18127.1 ORY47722.1 - 2.7e-14 53.4 0.4 6.9e-14 52.1 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5598) LST1 PF05083.13 ORY47722.1 - 0.06 13.6 0.6 0.13 12.5 0.6 1.5 1 0 0 1 1 1 0 LST-1 protein PhoQ_Sensor PF08918.10 ORY47722.1 - 0.061 13.2 1.0 0.11 12.3 1.0 1.3 1 0 0 1 1 1 0 PhoQ Sensor Nup84_Nup100 PF04121.13 ORY47723.1 - 1.5e-145 486.2 0.0 1.7e-145 486.0 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 Ank_2 PF12796.7 ORY47724.1 - 1e-06 29.2 0.1 3.8e-06 27.4 0.1 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY47724.1 - 1.2e-06 28.7 0.9 8.5e-06 26.0 0.1 2.4 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 ORY47724.1 - 3.9e-06 27.0 0.0 1.5e-05 25.1 0.0 2.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY47724.1 - 1.6e-05 24.9 0.0 0.00063 20.0 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 ORY47724.1 - 0.0033 17.9 0.8 0.12 13.0 0.1 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) FA_desaturase PF00487.24 ORY47725.1 - 5e-19 69.1 17.0 7.5e-19 68.6 17.0 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 ORY47725.1 - 2.9e-14 52.9 0.0 6.4e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF730 PF05325.11 ORY47725.1 - 0.27 11.3 0.8 2.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF730) FA_desaturase PF00487.24 ORY47726.1 - 1.3e-17 64.5 20.6 2.1e-17 63.8 20.6 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 ORY47726.1 - 1.5e-14 53.9 0.0 3.4e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DNA_ligase_A_M PF01068.21 ORY47727.1 - 1.2e-61 207.9 0.0 2.5e-61 206.9 0.0 1.5 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 ORY47727.1 - 1.1e-46 159.4 0.4 1.8e-46 158.6 0.4 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 ORY47727.1 - 3.7e-25 88.4 0.0 7.2e-25 87.5 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 ORY47727.1 - 4.3e-06 27.1 0.0 8.9e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 RNA ligase AAA PF00004.29 ORY47727.1 - 0.11 12.9 1.2 0.29 11.6 1.2 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DNA_ligase_OB_2 PF14743.6 ORY47727.1 - 0.16 12.0 0.2 22 5.2 0.1 2.9 2 0 0 2 2 2 0 DNA ligase OB-like domain DUF3530 PF12048.8 ORY47728.1 - 6.4 6.1 12.5 0.16 11.3 6.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) Metallophos PF00149.28 ORY47729.1 - 0.047 14.2 0.0 0.053 14.0 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase LRR_4 PF12799.7 ORY47730.1 - 4e-07 30.3 8.4 0.00038 20.8 0.1 4.6 2 2 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY47730.1 - 3.6e-05 23.5 6.6 0.0031 17.3 0.9 3.3 1 1 2 3 3 3 2 Leucine rich repeat F-box-like PF12937.7 ORY47730.1 - 0.00016 21.5 2.2 0.00022 21.0 0.7 2.0 2 0 0 2 2 2 1 F-box-like LRR_9 PF14580.6 ORY47730.1 - 0.0043 16.6 0.2 0.013 15.0 0.1 1.9 1 1 0 1 1 1 1 Leucine-rich repeat F-box PF00646.33 ORY47730.1 - 0.0077 16.1 0.1 0.03 14.2 0.1 2.1 1 0 0 1 1 1 1 F-box domain Pkinase PF00069.25 ORY47732.1 - 6.4e-10 38.8 0.0 1.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 ORY47732.1 - 0.0095 15.9 0.1 0.016 15.2 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family APC_rep PF18797.1 ORY47732.1 - 0.08 13.9 0.0 0.3 12.0 0.0 2.0 1 0 0 1 1 1 0 Adenomatous polyposis coli (APC) repeat eIF-5_eIF-2B PF01873.17 ORY47733.1 - 4.3e-39 133.0 0.1 5.9e-39 132.6 0.1 1.1 1 0 0 1 1 1 1 Domain found in IF2B/IF5 DUF2752 PF10825.8 ORY47733.1 - 0.02 14.9 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) Paf67 PF10255.9 ORY47734.1 - 1.9e-132 442.1 1.9 4e-123 411.4 0.9 2.4 2 1 1 3 3 3 2 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 ORY47734.1 - 0.00013 21.8 0.0 0.046 13.8 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY47734.1 - 0.001 18.8 0.0 0.16 11.9 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY47734.1 - 0.0041 17.4 0.0 0.041 14.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY47734.1 - 0.05 13.8 0.3 0.17 12.1 0.3 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TauD PF02668.16 ORY47735.1 - 2.3e-30 106.3 1.5 1.8e-29 103.4 1.5 2.2 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Septin PF00735.18 ORY47736.1 - 8.7e-99 330.3 0.4 2.1e-98 329.1 0.4 1.6 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 ORY47736.1 - 6.9e-08 32.6 0.0 1.5e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY47736.1 - 4.1e-05 23.5 0.4 0.00017 21.6 0.1 2.1 2 1 0 2 2 1 1 RsgA GTPase AIG1 PF04548.16 ORY47736.1 - 0.00011 21.7 0.0 0.0002 20.8 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 ORY47736.1 - 0.00018 21.2 0.0 0.00037 20.1 0.0 1.5 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.27 ORY47736.1 - 0.00035 20.2 0.1 0.0042 16.6 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Pox_A32 PF04665.12 ORY47736.1 - 0.00044 19.8 0.1 0.00088 18.8 0.1 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_22 PF13401.6 ORY47736.1 - 0.0014 19.0 0.1 0.0054 17.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 ORY47736.1 - 0.0038 16.8 0.0 0.0069 15.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region RNA_helicase PF00910.22 ORY47736.1 - 0.0061 16.9 0.0 0.02 15.3 0.0 2.0 2 0 0 2 2 1 1 RNA helicase IIGP PF05049.13 ORY47736.1 - 0.007 15.5 0.4 0.014 14.4 0.0 1.6 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.6 ORY47736.1 - 0.01 16.3 1.4 0.027 14.8 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 ORY47736.1 - 0.016 14.6 0.0 0.041 13.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 ORY47736.1 - 0.018 15.2 0.0 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FOXP-CC PF16159.5 ORY47736.1 - 0.018 15.6 3.7 0.023 15.3 0.7 2.5 1 1 1 2 2 2 0 FOXP coiled-coil domain ABC_tran PF00005.27 ORY47736.1 - 0.038 14.5 0.1 0.12 12.9 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 ORY47736.1 - 0.045 13.5 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 ORY47736.1 - 0.074 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain MeaB PF03308.16 ORY47736.1 - 0.11 11.5 0.4 0.31 10.0 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 ORY47736.1 - 0.49 10.4 5.7 13 5.8 0.0 3.2 2 1 1 3 3 3 0 Dynamin family Exonuc_VII_L PF02601.15 ORY47736.1 - 0.68 9.4 4.8 1.3 8.5 4.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF29 PF01724.16 ORY47736.1 - 0.76 10.0 6.7 2.7 8.2 6.7 2.0 1 1 0 1 1 1 0 Domain of unknown function DUF29 DUF3597 PF12200.8 ORY47736.1 - 5.1 7.6 6.3 15 6.2 6.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) CDC27 PF09507.10 ORY47737.1 - 0.0064 15.9 22.1 0.007 15.8 22.1 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 PPP4R2 PF09184.11 ORY47737.1 - 0.013 15.1 11.5 0.015 14.9 11.5 1.1 1 0 0 1 1 1 0 PPP4R2 Nop14 PF04147.12 ORY47737.1 - 0.048 11.9 14.9 0.05 11.8 14.9 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 ORY47737.1 - 0.15 11.3 10.9 0.21 10.9 10.9 1.1 1 0 0 1 1 1 0 NOA36 protein TFB6 PF17110.5 ORY47737.1 - 1.1 8.9 5.0 1.4 8.6 5.0 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH RXT2_N PF08595.11 ORY47737.1 - 1.5 8.8 9.7 2.6 8.1 9.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4746 PF15928.5 ORY47737.1 - 2 7.8 13.4 2.5 7.4 13.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CDC45 PF02724.14 ORY47737.1 - 2 6.6 16.2 2.2 6.5 16.2 1.3 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 ORY47737.1 - 2.1 8.8 13.7 5 7.6 13.7 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SAPS PF04499.15 ORY47737.1 - 2.3 6.9 6.7 2.5 6.8 6.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Merozoite_SPAM PF07133.11 ORY47737.1 - 2.6 8.0 24.1 4 7.4 24.1 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF2052 PF09747.9 ORY47737.1 - 6.4 6.9 21.6 9.4 6.3 21.6 1.3 1 1 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) EBV-NA3 PF05009.12 ORY47737.1 - 8.4 5.8 6.8 11 5.4 6.8 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) UPF0560 PF10577.9 ORY47737.1 - 8.8 4.7 16.0 11 4.3 16.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Nucleo_P87 PF07267.11 ORY47737.1 - 9.4 5.0 9.1 11 4.7 9.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4820 PF16091.5 ORY47737.1 - 9.6 5.5 10.3 12 5.1 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) HSA PF07529.13 ORY47738.1 - 8.6e-14 51.6 0.1 2e-13 50.4 0.1 1.6 1 0 0 1 1 1 1 HSA S6OS1 PF15676.5 ORY47738.1 - 0.054 12.0 0.1 0.077 11.5 0.1 1.1 1 0 0 1 1 1 0 Six6 opposite strand transcript 1 family Peptidase_S28 PF05577.12 ORY47740.1 - 6.6e-05 21.9 0.0 8.3e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 LapA_dom PF06305.11 ORY47740.1 - 0.18 11.6 0.1 0.27 11.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Peptidase_S28 PF05577.12 ORY47741.1 - 1.8e-63 214.9 2.9 2.1e-63 214.6 2.9 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Acyl_transf_1 PF00698.21 ORY47742.1 - 1.4e-28 100.4 0.3 2.2e-28 99.7 0.3 1.3 1 1 0 1 1 1 1 Acyl transferase domain Lysine_decarbox PF03641.14 ORY47743.1 - 4.9e-41 139.9 0.1 7.6e-41 139.3 0.1 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 ORY47743.1 - 6.5e-10 38.8 0.1 7.7e-10 38.6 0.1 1.2 1 0 0 1 1 1 1 SLOG cluster4 family Peptidase_S28 PF05577.12 ORY47744.1 - 2e-76 257.6 0.7 2.6e-76 257.2 0.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 ORY47744.1 - 0.0096 15.6 0.8 0.022 14.4 0.1 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY47744.1 - 0.039 13.4 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lysine_decarbox PF03641.14 ORY47745.1 - 9.9e-40 135.7 0.1 1.2e-39 135.4 0.1 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 ORY47745.1 - 1.9e-16 60.0 0.3 2.2e-16 59.8 0.3 1.1 1 0 0 1 1 1 1 SLOG cluster4 family DNA_processg_A PF02481.15 ORY47745.1 - 0.13 11.5 0.1 0.21 10.8 0.1 1.3 1 0 0 1 1 1 0 DNA recombination-mediator protein A STI1 PF17830.1 ORY47746.1 - 1.1e-16 60.5 4.9 5.6e-08 32.6 0.6 2.5 2 0 0 2 2 2 2 STI1 domain Nif11 PF07862.11 ORY47746.1 - 1.7e-05 25.0 2.9 0.21 11.9 0.1 4.1 3 1 0 3 3 3 2 Nif11 domain BSD PF03909.17 ORY47746.1 - 0.0014 18.6 0.7 0.07 13.1 0.1 3.2 2 1 1 3 3 3 1 BSD domain DUF5568 PF17724.1 ORY47746.1 - 0.055 13.3 1.9 0.086 12.7 1.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5568) MCM PF00493.23 ORY47747.1 - 5.7e-103 342.8 0.0 9.2e-103 342.1 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY47747.1 - 1.5e-32 112.1 2.7 2.7e-32 111.3 2.7 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORY47747.1 - 1.6e-18 66.9 3.4 2e-18 66.5 1.4 2.3 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 ORY47747.1 - 7e-18 65.1 0.6 2.1e-17 63.6 0.6 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ORY47747.1 - 1.1e-08 34.8 0.1 4.9e-06 26.1 0.0 2.9 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ORY47747.1 - 9.6e-07 28.9 0.0 4.3e-06 26.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 ORY47747.1 - 0.0065 16.3 0.0 0.02 14.7 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 ORY47747.1 - 0.061 13.0 0.1 0.45 10.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.6 ORY47747.1 - 0.067 13.6 0.4 1.8 8.9 0.1 3.2 2 1 0 2 2 2 0 AAA ATPase domain 3Beta_HSD PF01073.19 ORY47748.1 - 6.1e-72 242.0 0.0 7.5e-72 241.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY47748.1 - 1.1e-31 110.1 0.0 1.5e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 ORY47748.1 - 3.2e-17 62.6 0.0 4.7e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 ORY47748.1 - 8.3e-17 61.2 0.6 2e-13 50.1 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 ORY47748.1 - 9.7e-16 58.2 0.0 1.4e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ORY47748.1 - 1.5e-12 47.5 0.1 1.3e-09 38.0 0.0 2.3 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 ORY47748.1 - 3.2e-06 26.5 0.1 1.1e-05 24.8 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 ORY47748.1 - 3e-05 24.0 0.3 0.0087 16.0 0.1 3.0 2 1 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 ORY47748.1 - 0.00031 21.0 0.1 0.00073 19.8 0.1 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 ORY47748.1 - 0.0022 17.6 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 ORY47748.1 - 0.012 15.9 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain DUF2187 PF09953.9 ORY47748.1 - 0.075 13.0 0.0 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2187) BRCA2 PF00634.18 ORY47748.1 - 0.3 10.8 2.0 9.5 6.0 0.1 2.8 3 0 0 3 3 3 0 BRCA2 repeat Glyco_hydro_18 PF00704.28 ORY47749.1 - 1.7e-102 343.4 13.5 6.3e-57 193.7 4.9 3.1 2 1 1 3 3 3 3 Glycosyl hydrolases family 18 SNAD3 PF18749.1 ORY47749.1 - 0.023 13.9 0.0 5.6 6.0 0.0 2.2 2 0 0 2 2 2 0 Secreted Novel AID/APOBEC-like Deaminase 3 Glyco_hydro_114 PF03537.13 ORY47749.1 - 0.044 13.1 0.0 0.23 10.8 0.0 2.0 2 0 0 2 2 2 0 Glycoside-hydrolase family GH114 RVT_1 PF00078.27 ORY47750.1 - 1.5e-08 34.4 0.0 1.1e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) LRR_8 PF13855.6 ORY47751.1 - 4.6e-08 32.7 5.5 0.00062 19.5 0.7 4.0 3 1 1 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 ORY47751.1 - 2.3e-05 24.3 7.4 6.5 7.7 0.1 6.8 8 1 0 8 8 8 2 Leucine Rich Repeat LRR_4 PF12799.7 ORY47751.1 - 8.3e-05 22.9 10.8 0.0005 20.4 1.6 4.9 2 2 4 6 6 6 2 Leucine Rich repeats (2 copies) RRM_1 PF00076.22 ORY47752.1 - 6.8e-07 29.0 0.0 5.7e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_S28 PF05577.12 ORY47753.1 - 2.2e-41 142.1 0.0 3e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S28 PF05577.12 ORY47754.1 - 6.8e-23 81.2 0.2 8.4e-23 80.8 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S28 PF05577.12 ORY47755.1 - 4.7e-35 121.2 0.0 5.4e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 ORY47755.1 - 0.041 13.3 0.0 0.053 13.0 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family Vps23_core PF09454.10 ORY47755.1 - 0.17 11.9 0.0 1.4 8.9 0.0 2.0 2 0 0 2 2 2 0 Vps23 core domain Peptidase_S28 PF05577.12 ORY47756.1 - 3.1e-17 62.5 3.8 3.9e-17 62.2 3.8 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Mannosyl_trans3 PF11051.8 ORY47757.1 - 0.0001 21.8 0.3 0.017 14.5 0.3 3.2 1 1 0 1 1 1 1 Mannosyltransferase putative DUF4479 PF14794.6 ORY47757.1 - 0.089 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) DUF1593 PF07632.11 ORY47757.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) DUF4586 PF15239.6 ORY47758.1 - 4.4e-44 151.9 12.4 1.6e-40 140.2 1.4 3.0 1 1 2 3 3 3 3 Domain of unknown function (DUF4586) Uso1_p115_head PF04869.14 ORY47758.1 - 0.12 11.4 0.1 0.18 10.9 0.1 1.1 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, head region TPR_2 PF07719.17 ORY47759.1 - 0.24 11.6 6.7 10 6.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF563 PF04577.14 ORY47760.1 - 5.6e-16 59.3 0.0 1.2e-15 58.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) HLH PF00010.26 ORY47761.1 - 1.1e-07 31.7 0.5 4.8e-07 29.6 0.0 2.2 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain TALPID3 PF15324.6 ORY47761.1 - 0.05 11.3 3.8 0.056 11.1 3.8 1.0 1 0 0 1 1 1 0 Hedgehog signalling target Alveol-reg_P311 PF11092.8 ORY47761.1 - 0.12 12.5 0.0 0.37 10.9 0.0 1.8 2 0 0 2 2 2 0 Neuronal protein 3.1 (p311) Clr2_transil PF16761.5 ORY47762.1 - 2.6e-17 63.4 0.1 5.4e-17 62.4 0.1 1.5 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 BSP_II PF05432.11 ORY47765.1 - 0.072 12.8 16.9 0.1 12.3 16.9 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CobT PF06213.12 ORY47765.1 - 1.4 8.3 10.6 3.1 7.1 10.6 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.12 ORY47765.1 - 4.5 6.6 16.9 7.3 5.9 16.9 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 ORY47765.1 - 4.7 5.4 9.2 6.1 5.0 9.2 1.2 1 0 0 1 1 1 0 CDC45-like protein CAMP_factor PF07373.11 ORY47766.1 - 0.35 10.4 2.0 0.71 9.4 0.1 2.0 2 0 0 2 2 2 0 CAMP factor (Cfa) DUF572 PF04502.13 ORY47767.1 - 1.8e-82 277.7 1.6 3.2e-82 276.8 1.6 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF572) AAA_10 PF12846.7 ORY47767.1 - 0.014 14.4 1.4 0.019 13.9 1.4 1.1 1 0 0 1 1 1 0 AAA-like domain TetR_C_31 PF17940.1 ORY47767.1 - 0.014 15.6 0.8 0.026 14.7 0.8 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DNA_RNApol_7kD PF03604.13 ORY47767.1 - 0.082 12.6 0.4 10 5.9 0.1 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit HypA PF01155.19 ORY47767.1 - 0.4 10.7 2.4 0.99 9.4 0.5 2.4 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PhnA_Zn_Ribbon PF08274.12 ORY47767.1 - 1.2 9.2 2.8 2 8.4 0.3 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon DUF2175 PF09943.9 ORY47767.1 - 3.9 7.8 5.3 7.9 6.8 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF5321 PF17254.2 ORY47767.1 - 7.2 6.0 10.3 0.51 9.8 4.2 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5321) Vps16_N PF04841.13 ORY47768.1 - 2.3e-90 303.3 0.0 3e-90 302.9 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 ORY47768.1 - 1.9e-65 221.0 4.5 3e-65 220.4 4.5 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 ORY47768.1 - 0.00047 20.4 0.2 1.2 9.5 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Cas9_REC PF16592.5 ORY47768.1 - 0.01 14.6 0.2 0.015 14.1 0.2 1.1 1 0 0 1 1 1 0 REC lobe of CRISPR-associated endonuclease Cas9 Glutaminase PF04960.15 ORY47769.1 - 1.2e-111 372.6 0.0 1.5e-111 372.2 0.0 1.1 1 0 0 1 1 1 1 Glutaminase CENP-F_leu_zip PF10473.9 ORY47770.1 - 0.0011 19.0 8.5 0.0013 18.8 8.5 1.1 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PI3K_P85_iSH2 PF16454.5 ORY47770.1 - 0.0027 17.3 5.1 0.0031 17.1 5.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF3450 PF11932.8 ORY47770.1 - 0.0033 16.8 3.9 0.0035 16.7 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) KASH_CCD PF14662.6 ORY47770.1 - 0.0063 16.4 4.8 0.0069 16.2 4.8 1.0 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 ORY47770.1 - 0.01 16.1 4.9 0.01 16.1 4.9 1.0 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 ORY47770.1 - 0.014 15.2 10.0 0.18 11.6 0.9 2.1 1 1 1 2 2 2 0 Septum formation initiator APG6_N PF17675.1 ORY47770.1 - 0.035 14.6 11.2 0.046 14.2 11.2 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF4795 PF16043.5 ORY47770.1 - 0.042 13.4 4.5 0.048 13.3 4.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) ERM PF00769.19 ORY47770.1 - 0.049 13.5 9.0 0.055 13.3 9.0 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF5082 PF16888.5 ORY47770.1 - 0.06 13.6 3.4 0.073 13.3 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) NRBF2 PF08961.10 ORY47770.1 - 0.062 12.9 2.7 0.073 12.7 2.7 1.1 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator Fungal_TACC PF12709.7 ORY47770.1 - 0.069 13.6 3.7 0.11 13.0 2.5 1.8 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins HMMR_N PF15905.5 ORY47770.1 - 0.1 12.0 8.1 0.12 11.9 8.1 1.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal AstE_AspA PF04952.14 ORY47770.1 - 0.1 11.6 0.2 0.12 11.5 0.2 1.0 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family bZIP_2 PF07716.15 ORY47770.1 - 0.23 11.5 7.7 1.7 8.8 0.2 2.3 2 0 0 2 2 2 0 Basic region leucine zipper DEC-1_N PF04625.13 ORY47770.1 - 0.27 10.2 1.5 0.32 10.0 1.5 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF5320 PF17253.2 ORY47770.1 - 0.37 11.9 2.4 0.54 11.4 2.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5320) TMF_DNA_bd PF12329.8 ORY47770.1 - 0.47 10.5 11.7 0.61 10.1 11.7 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.21 ORY47770.1 - 0.58 10.3 8.6 0.099 12.8 1.7 2.1 1 1 1 2 2 2 0 bZIP transcription factor ZapB PF06005.12 ORY47770.1 - 0.66 10.5 10.8 0.079 13.4 5.6 1.8 1 1 1 2 2 2 0 Cell division protein ZapB GIT_CC PF16559.5 ORY47770.1 - 0.73 9.7 5.4 0.65 9.9 2.4 1.9 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Spc7 PF08317.11 ORY47770.1 - 1.1 8.0 7.9 1.4 7.8 7.9 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Bap31_Bap29_C PF18035.1 ORY47770.1 - 4 7.5 9.7 2.2 8.4 5.5 2.4 1 1 1 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4140 PF13600.6 ORY47770.1 - 6.6 7.2 7.9 42 4.7 7.9 2.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) GSH_synth_ATP PF03917.17 ORY47771.1 - 6.9e-114 380.5 0.0 1e-113 379.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 ORY47771.1 - 1e-33 115.9 0.0 2.2e-33 114.7 0.0 1.6 2 0 0 2 2 2 1 Eukaryotic glutathione synthase Thiolase_C PF02803.18 ORY47772.1 - 1.7e-10 40.6 0.0 5.1e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain Thiolase_N PF00108.23 ORY47772.1 - 1.1e-06 28.2 0.0 6.9e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Ketoacyl-synt_C PF02801.22 ORY47772.1 - 0.025 14.6 0.9 8.4 6.4 0.0 2.7 3 0 0 3 3 3 0 Beta-ketoacyl synthase, C-terminal domain Glyco_hydro_35 PF01301.19 ORY47773.1 - 1.3e-93 314.1 1.4 1.8e-93 313.6 1.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 ORY47773.1 - 6.7e-08 32.3 0.1 1.8e-07 30.9 0.1 1.7 1 1 0 1 1 1 1 Beta-galactosidase GHD PF17834.1 ORY47773.1 - 4.1e-07 29.9 0.0 8.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Beta-sandwich domain in beta galactosidase AIRS_C PF02769.22 ORY47774.1 - 1.8e-08 34.7 0.0 1.9e-07 31.3 0.0 2.2 1 1 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 ORY47774.1 - 0.011 16.4 0.6 0.027 15.1 0.2 1.8 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain NAF PF03822.14 ORY47775.1 - 0.076 13.2 0.9 0.24 11.6 0.6 2.0 2 1 0 2 2 2 0 NAF domain DUF484 PF04340.12 ORY47775.1 - 0.71 9.5 6.0 0.98 9.1 5.5 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF484 Cep57_MT_bd PF06657.13 ORY47775.1 - 2.6 8.5 14.1 1.7 9.2 2.3 2.8 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Fzo_mitofusin PF04799.13 ORY47775.1 - 3.8 7.1 8.8 1.5 8.3 5.3 2.1 1 1 1 2 2 2 0 fzo-like conserved region YkyA PF10368.9 ORY47775.1 - 6.2 6.4 22.3 17 5.0 22.3 1.7 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein Rgp1 PF08737.10 ORY47775.1 - 9.8 5.2 15.7 7.1 5.7 11.3 1.8 1 1 1 2 2 2 0 Rgp1 DUF2075 PF09848.9 ORY47776.1 - 0.015 14.6 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.17 ORY47776.1 - 0.037 14.1 0.0 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain DAP3 PF10236.9 ORY47776.1 - 0.064 12.4 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 ORY47776.1 - 0.087 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 ORY47776.1 - 0.23 10.8 0.0 0.38 10.1 0.0 1.2 1 0 0 1 1 1 0 KaiC CFEM PF05730.11 ORY47779.1 - 0.044 13.9 2.1 0.096 12.8 2.1 1.6 1 0 0 1 1 1 0 CFEM domain CAP PF00188.26 ORY47780.1 - 1.4e-09 38.9 0.0 2.5e-09 38.0 0.0 1.4 1 1 0 1 1 1 1 Cysteine-rich secretory protein family WD40 PF00400.32 ORY47781.1 - 6.3e-07 30.0 2.9 0.018 15.9 0.4 5.2 5 0 0 5 5 5 1 WD domain, G-beta repeat Utp8 PF10395.9 ORY47781.1 - 0.002 16.7 0.4 0.002 16.7 0.4 1.6 2 0 0 2 2 2 1 Utp8 family LisH PF08513.11 ORY47781.1 - 0.0022 17.9 0.0 0.0057 16.6 0.0 1.7 2 0 0 2 2 2 1 LisH Adhes-Ig_like PF09085.10 ORY47782.1 - 0.072 13.2 0.0 0.081 13.1 0.0 1.1 1 0 0 1 1 1 0 Adhesion molecule, immunoglobulin-like Rep_fac-A_3 PF08661.11 ORY47783.1 - 1.1e-12 48.2 0.5 1.2e-12 48.1 0.5 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ribosomal_S7e PF01251.18 ORY47784.1 - 2e-84 282.0 5.2 2.2e-84 281.8 5.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF682 PF05081.12 ORY47784.1 - 0.15 11.8 0.2 15 5.3 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF682) DUF5535 PF17687.1 ORY47785.1 - 0.057 13.6 0.0 0.065 13.4 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5535) TMEM108 PF15759.5 ORY47787.1 - 0.011 14.8 0.8 0.012 14.7 0.8 1.0 1 0 0 1 1 1 0 TMEM108 family Ribosomal_L16 PF00252.18 ORY47788.1 - 6e-42 142.8 0.1 7.8e-42 142.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Glyco_hydro_16 PF00722.21 ORY47789.1 - 1.9e-30 105.6 0.8 4.1e-30 104.5 0.8 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 ORY47790.1 - 1.4e-26 93.1 2.6 1.4e-26 93.1 2.6 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 PAP1 PF08601.10 ORY47790.1 - 1.3 8.7 11.8 1.9 8.2 11.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF5305 PF17231.2 ORY47790.1 - 3.2 7.1 6.4 4.7 6.5 6.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Glyco_hydro_16 PF00722.21 ORY47791.1 - 9e-28 96.9 2.7 1.2e-27 96.5 2.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 LRR_8 PF13855.6 ORY47792.1 - 8.8e-12 44.6 11.5 0.00057 19.6 3.0 3.4 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY47792.1 - 6.7e-10 39.1 25.7 0.00072 19.9 2.8 4.4 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY47792.1 - 1.4e-05 25.0 18.0 0.18 12.5 0.1 5.5 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_6 PF13516.6 ORY47792.1 - 0.0038 17.2 8.3 0.2 11.8 0.0 3.8 4 0 0 4 4 4 2 Leucine Rich repeat DLH PF01738.18 ORY47793.1 - 3.7e-16 59.3 0.2 4.6e-16 59.0 0.2 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 ORY47793.1 - 7.3e-05 22.5 0.0 9e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY47793.1 - 0.029 13.6 0.1 0.055 12.7 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY47793.1 - 0.046 14.3 0.0 0.056 14.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family F-box-like PF12937.7 ORY47794.1 - 0.00019 21.3 0.1 0.00044 20.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY47794.1 - 0.042 13.7 0.2 0.11 12.4 0.2 1.6 1 0 0 1 1 1 0 F-box domain Hydrolase_4 PF12146.8 ORY47795.1 - 1.8e-19 70.0 0.0 3.4e-19 69.0 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY47795.1 - 5e-19 68.9 0.0 1e-16 61.4 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY47795.1 - 4.9e-16 60.0 0.0 5.7e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 ORY47795.1 - 3.1e-05 22.8 0.0 0.0002 20.2 0.0 1.8 2 0 0 2 2 2 1 Ndr family Peptidase_S15 PF02129.18 ORY47795.1 - 0.00035 20.2 0.0 0.00063 19.4 0.0 1.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 ORY47795.1 - 0.0073 16.3 0.0 0.015 15.2 0.0 1.5 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 ORY47795.1 - 0.0093 15.6 0.0 0.018 14.7 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Acyl_transf_2 PF02273.15 ORY47795.1 - 0.059 12.6 0.0 0.081 12.1 0.0 1.1 1 0 0 1 1 1 0 Acyl transferase Palm_thioest PF02089.15 ORY47795.1 - 0.082 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase CENP-Q PF13094.6 ORY47796.1 - 0.00039 20.7 11.6 0.0063 16.7 0.8 2.7 2 0 0 2 2 2 2 CENP-Q, a CENPA-CAD centromere complex subunit UAA PF08449.11 ORY47797.1 - 9.5e-51 172.8 18.7 1.1e-50 172.6 18.7 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 ORY47797.1 - 4.3e-06 26.9 30.4 0.0023 18.1 12.5 3.3 3 1 0 3 3 3 3 EamA-like transporter family MtrE PF04206.12 ORY47797.1 - 0.022 14.1 0.2 0.022 14.1 0.2 2.7 2 1 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit E PIG-Y PF15159.6 ORY47797.1 - 0.3 12.0 0.2 0.3 12.0 0.2 2.9 3 0 0 3 3 3 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y HRG PF16954.5 ORY47797.1 - 1.7 9.1 7.0 19 5.7 0.3 3.8 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene DUF1003 PF06210.11 ORY47797.1 - 3.8 7.7 5.8 2 8.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1003) Glyco_hydro_18 PF00704.28 ORY47798.1 - 3.5e-54 184.7 0.0 4e-54 184.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Peptidase_M50B PF13398.6 ORY47799.1 - 1e-34 120.0 26.0 2.8e-32 112.0 26.0 2.0 1 1 0 1 1 1 1 Peptidase M50B-like ETRAMP PF09716.10 ORY47800.1 - 0.00029 20.9 0.4 0.00052 20.0 0.4 1.4 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) DUF2749 PF10907.8 ORY47800.1 - 0.044 13.9 2.0 0.11 12.6 2.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Zip PF02535.22 ORY47800.1 - 0.069 12.4 0.2 0.1 11.8 0.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter GRA6 PF05084.13 ORY47800.1 - 0.65 9.9 5.0 0.13 12.2 0.8 1.7 2 0 0 2 2 2 0 Granule antigen protein (GRA6) DUF4231 PF14015.6 ORY47800.1 - 1 9.9 3.1 17 6.0 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) WD40 PF00400.32 ORY47801.1 - 3.5e-14 52.9 1.8 4.9e-05 24.0 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_2 PF13360.6 ORY47801.1 - 0.042 13.4 0.1 0.093 12.3 0.1 1.5 1 1 0 1 1 1 0 PQQ-like domain WSD PF15613.6 ORY47802.1 - 0.044 14.3 10.5 0.053 14.0 0.3 4.4 3 1 1 4 4 4 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Rhabdo_ncap PF00945.18 ORY47802.1 - 1.2 7.9 5.2 14 4.4 5.0 2.3 2 0 0 2 2 2 0 Rhabdovirus nucleocapsid protein IFT57 PF10498.9 ORY47802.1 - 1.9 7.3 17.9 2.8 6.8 0.7 2.6 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 NOA36 PF06524.12 ORY47802.1 - 9 5.5 11.5 22 4.3 11.5 1.6 1 0 0 1 1 1 0 NOA36 protein HisG PF01634.18 ORY47803.1 - 1.4e-52 177.8 0.1 1.9e-52 177.4 0.1 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 ORY47803.1 - 1.9e-29 101.6 0.5 3.9e-29 100.6 0.5 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 ORY47803.1 - 8.3e-08 32.4 0.1 1.2e-07 31.9 0.1 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.7 ORY47803.1 - 0.004 16.8 0.0 0.0066 16.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein LRR_8 PF13855.6 ORY47804.1 - 8.1e-13 47.9 4.6 2.1e-05 24.2 0.1 4.1 4 0 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 ORY47804.1 - 1e-08 35.3 15.1 0.00073 19.9 0.5 5.0 2 1 5 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY47804.1 - 1.3e-06 28.1 16.5 0.062 13.9 0.1 6.0 6 0 0 6 6 6 3 Leucine Rich Repeat F-box PF00646.33 ORY47804.1 - 0.0022 17.8 0.6 0.0048 16.7 0.6 1.6 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.6 ORY47804.1 - 0.034 14.2 10.8 1.9 8.8 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich repeat F-box-like PF12937.7 ORY47804.1 - 0.091 12.7 0.2 0.091 12.7 0.2 1.9 2 0 0 2 2 2 0 F-box-like HORMA PF02301.18 ORY47805.1 - 2e-60 204.0 0.5 2.5e-60 203.7 0.5 1.1 1 0 0 1 1 1 1 HORMA domain DUF3439 PF11921.8 ORY47805.1 - 1.3 9.0 7.6 3.1 7.8 7.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Abhydrolase_3 PF07859.13 ORY47807.1 - 1.1e-25 90.7 0.0 1.6e-25 90.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY47807.1 - 4.1e-06 25.9 0.0 0.00024 20.1 0.0 2.0 2 0 0 2 2 2 2 Steryl acetyl hydrolase zf_C2H2_ZHX PF18387.1 ORY47809.1 - 0.00037 20.1 2.0 0.74 9.5 0.2 2.5 2 0 0 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain zf-Di19 PF05605.12 ORY47809.1 - 0.0055 17.0 9.5 0.15 12.4 0.5 2.9 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 ORY47809.1 - 0.01 16.5 4.6 2 9.1 0.1 3.1 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 ORY47809.1 - 0.057 13.9 5.2 1.2 9.7 0.1 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY47809.1 - 0.38 11.7 0.2 0.38 11.7 0.2 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger Sugar_tr PF00083.24 ORY47810.1 - 1.1e-34 120.2 20.2 4.1e-28 98.5 4.5 2.7 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY47810.1 - 1.5e-32 112.9 31.5 3e-32 111.9 31.5 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily PIGA PF08288.12 ORY47812.1 - 3.1e-40 136.7 0.1 7.9e-40 135.3 0.1 1.7 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.20 ORY47812.1 - 1.3e-29 102.9 0.0 3.7e-29 101.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORY47812.1 - 2.4e-29 102.5 0.3 4.1e-29 101.8 0.3 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 ORY47812.1 - 2.5e-23 83.0 0.4 3.8e-22 79.2 0.2 2.4 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ORY47812.1 - 1.5e-12 48.2 0.0 2.6e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 ORY47812.1 - 1.7e-05 24.8 0.0 2.7e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 ORY47812.1 - 0.0019 18.5 0.0 0.014 15.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 K-cyclin_vir_C PF09080.10 ORY47812.1 - 0.04 14.3 3.0 2.4 8.6 0.0 3.4 3 1 1 4 4 4 0 K cyclin, C terminal Mannosyl_trans3 PF11051.8 ORY47813.1 - 7.8e-32 110.7 0.0 1.5e-31 109.8 0.0 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative zf-C2H2_jaz PF12171.8 ORY47814.1 - 0.0018 18.5 0.4 0.0042 17.3 0.4 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY47814.1 - 0.15 12.5 0.4 0.48 10.9 0.4 1.9 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 ORY47814.1 - 8.9 7.5 13.6 0.25 12.3 0.7 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger LRR_8 PF13855.6 ORY47816.1 - 8e-07 28.7 14.0 0.00069 19.3 0.1 4.3 1 1 3 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 ORY47816.1 - 0.0003 21.1 19.9 0.0059 17.0 0.6 4.9 2 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY47816.1 - 0.022 15.3 14.2 0.61 10.8 0.1 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat F-box-like PF12937.7 ORY47816.1 - 0.08 12.9 0.3 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 F-box-like LRR_6 PF13516.6 ORY47816.1 - 4.5 7.6 13.2 2.1 8.6 0.3 4.7 4 0 0 4 4 4 0 Leucine Rich repeat Peptidase_M20 PF01546.28 ORY47817.1 - 6.4e-32 110.9 0.0 9e-32 110.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY47817.1 - 2.1e-13 50.1 0.0 6.4e-13 48.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain WG_beta_rep PF14903.6 ORY47817.1 - 0.046 14.0 0.1 0.14 12.4 0.1 1.9 1 0 0 1 1 1 0 WG containing repeat Arf PF00025.21 ORY47818.1 - 7.1e-72 240.5 0.1 8.1e-72 240.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORY47818.1 - 3.1e-15 56.5 0.0 4.2e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 ORY47818.1 - 1.3e-13 50.8 0.0 1.6e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 ORY47818.1 - 3e-13 49.7 0.0 3.4e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 ORY47818.1 - 3.1e-12 46.3 0.4 2.1e-08 33.7 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 ORY47818.1 - 3.7e-10 39.5 0.0 4.7e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY47818.1 - 3.5e-05 23.9 0.0 5.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 ORY47818.1 - 0.00029 20.5 0.9 0.071 12.7 0.0 2.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 ORY47818.1 - 0.0023 17.8 0.0 0.0031 17.4 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 ORY47818.1 - 0.0079 15.8 0.2 0.014 15.1 0.2 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_25 PF13481.6 ORY47818.1 - 0.011 15.4 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 ORY47818.1 - 0.012 15.5 0.1 4.9 7.0 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 ORY47818.1 - 0.021 15.4 0.5 0.095 13.2 0.5 1.8 1 1 0 1 1 1 0 ABC transporter AAA PF00004.29 ORY47818.1 - 0.055 13.9 0.0 0.073 13.5 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 ORY47818.1 - 0.077 12.9 1.2 7.7 6.4 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_7 PF12775.7 ORY47818.1 - 0.096 12.2 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 ORY47818.1 - 0.11 12.7 0.1 0.14 12.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain GST_C_2 PF13410.6 ORY47819.1 - 6.3e-06 26.1 0.0 2.7e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY47819.1 - 0.0088 16.2 0.0 0.015 15.5 0.0 1.3 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 ORY47819.1 - 0.035 13.9 0.0 0.073 12.9 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY47819.1 - 0.056 13.6 0.0 0.08 13.1 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF507 PF04368.13 ORY47821.1 - 0.024 14.6 0.1 0.035 14.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF507) EB PF01683.18 ORY47822.1 - 5.7 7.3 14.5 1.3 9.4 1.8 3.2 2 1 1 3 3 3 0 EB module Sel1 PF08238.12 ORY47823.1 - 2.7e-105 342.4 46.3 5.8e-10 39.5 0.1 14.9 15 0 0 15 15 15 13 Sel1 repeat TPR_16 PF13432.6 ORY47823.1 - 1.2e-06 29.0 3.8 0.065 13.9 0.1 5.1 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY47823.1 - 3.7e-05 23.4 7.3 0.054 13.5 0.1 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY47823.1 - 0.017 15.5 2.6 9.4 6.9 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY47823.1 - 0.34 11.5 6.0 29 5.3 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Fib_succ_major PF09603.10 ORY47823.1 - 2.3 8.8 5.5 45 4.6 0.7 3.5 1 1 1 3 3 3 0 Fibrobacter succinogenes major domain (Fib_succ_major) TPR_10 PF13374.6 ORY47823.1 - 3.9 7.5 11.1 53 3.9 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat LRR_8 PF13855.6 ORY47825.1 - 6.3e-07 29.1 9.9 0.0012 18.6 0.2 3.6 2 1 1 3 3 3 3 Leucine rich repeat F-box PF00646.33 ORY47825.1 - 0.00022 21.0 0.2 0.00022 21.0 0.2 2.0 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 ORY47825.1 - 0.00031 20.9 12.7 0.24 12.1 0.1 5.6 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_4 PF12799.7 ORY47825.1 - 0.003 17.9 18.0 0.096 13.1 2.8 4.8 1 1 2 4 4 4 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORY47825.1 - 0.0041 17.0 1.2 0.012 15.4 0.1 2.3 2 0 0 2 2 2 1 F-box-like Spo7_2_N PF15407.6 ORY47825.1 - 0.034 13.8 0.1 7.5 6.3 0.0 3.5 3 0 0 3 3 3 0 Sporulation protein family 7 Syntaxin_2 PF14523.6 ORY47825.1 - 0.057 13.8 0.8 0.089 13.2 0.2 1.6 2 0 0 2 2 1 0 Syntaxin-like protein FH2 PF02181.23 ORY47825.1 - 0.068 12.3 0.6 0.098 11.8 0.6 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain MMgT PF10270.9 ORY47825.1 - 0.1 13.0 0.2 0.19 12.1 0.2 1.4 1 0 0 1 1 1 0 Membrane magnesium transporter DUF3760 PF12586.8 ORY47825.1 - 0.12 12.6 0.1 0.36 11.0 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) LRR_6 PF13516.6 ORY47825.1 - 0.34 11.1 5.9 2.1 8.6 0.3 3.6 3 0 0 3 3 3 0 Leucine Rich repeat DUF131 PF01998.17 ORY47825.1 - 4.9 6.9 5.1 3.4 7.4 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function DUF131 F-box PF00646.33 ORY47826.1 - 0.001 18.9 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY47826.1 - 0.035 14.0 0.2 0.13 12.2 0.0 2.0 2 0 0 2 2 2 0 F-box-like Foie-gras_1 PF11817.8 ORY47827.1 - 5.3e-38 131.1 0.0 5.4e-37 127.8 0.0 2.3 2 0 0 2 2 2 1 Foie gras liver health family 1 Gryzun PF07919.12 ORY47827.1 - 2.2e-24 86.2 0.0 1.3e-11 44.0 0.0 2.1 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.7 ORY47827.1 - 8.6e-07 28.9 0.0 1.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking T6SS_VasJ PF16989.5 ORY47827.1 - 0.00043 19.9 0.8 0.036 13.5 0.0 2.3 2 0 0 2 2 2 1 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ TPR_12 PF13424.6 ORY47827.1 - 0.0032 17.7 0.6 0.22 11.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TRAPPC10 PF12584.8 ORY47827.1 - 0.017 14.8 0.0 0.046 13.4 0.0 1.7 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 SNAP PF14938.6 ORY47827.1 - 0.27 10.6 0.9 0.45 9.9 0.0 1.7 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 ORY47827.1 - 2.1 8.6 4.3 7.6 6.8 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Fungal_trans PF04082.18 ORY47828.1 - 1.6e-28 99.5 0.5 8e-28 97.2 0.3 2.3 4 0 0 4 4 4 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY47828.1 - 1.6e-05 24.9 14.1 3.2e-05 24.0 14.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_8 PF13855.6 ORY47829.1 - 2.8e-11 43.0 13.5 0.00014 21.6 2.5 4.9 4 1 1 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 ORY47829.1 - 5.1e-08 33.1 17.2 1.1e-05 25.7 3.4 5.7 2 1 4 6 6 6 2 Leucine Rich repeats (2 copies) F-box PF00646.33 ORY47829.1 - 6.6e-05 22.7 0.1 0.00026 20.8 0.0 2.1 1 1 1 2 2 2 1 F-box domain LRR_1 PF00560.33 ORY47829.1 - 0.00088 19.5 17.2 0.17 12.5 0.7 6.4 5 1 0 5 5 5 2 Leucine Rich Repeat F-box_4 PF15966.5 ORY47829.1 - 0.052 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 F-box Proteasome_A_N PF10584.9 ORY47829.1 - 0.092 12.5 1.0 0.19 11.5 1.0 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Snapin_Pallidin PF14712.6 ORY47829.1 - 0.26 11.7 3.0 0.69 10.4 2.5 2.0 2 0 0 2 2 2 0 Snapin/Pallidin cNMP_binding PF00027.29 ORY47830.1 - 3.5e-21 75.1 0.0 9.9e-21 73.6 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 ORY47830.1 - 3.4e-05 23.2 5.0 5.4e-05 22.5 5.0 1.2 1 0 0 1 1 1 1 Ion transport protein DUF2207 PF09972.9 ORY47830.1 - 0.037 12.8 0.9 0.062 12.0 0.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Ion_trans_2 PF07885.16 ORY47830.1 - 0.07 13.1 2.3 0.15 12.0 2.3 1.6 1 0 0 1 1 1 0 Ion channel Atrophin-1 PF03154.15 ORY47832.1 - 2.3 6.4 6.4 2.7 6.1 6.4 1.2 1 0 0 1 1 1 0 Atrophin-1 family Homeodomain PF00046.29 ORY47833.1 - 3.3e-17 62.1 1.9 3.5e-17 62.0 1.9 1.0 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY47833.1 - 1.1e-06 28.4 0.2 1.5e-06 28.0 0.2 1.2 1 0 0 1 1 1 1 Homeobox KN domain HTH_28 PF13518.6 ORY47833.1 - 0.13 12.4 0.1 0.22 11.7 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain cNMP_binding PF00027.29 ORY47834.1 - 2.4e-15 56.3 0.0 6.4e-15 55.0 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain WD40 PF00400.32 ORY47836.1 - 1.1e-15 57.7 9.4 0.0035 18.1 0.2 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY47836.1 - 1.9e-05 24.8 0.0 0.033 14.5 0.0 3.6 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cadherin_4 PF17803.1 ORY47836.1 - 0.11 13.1 0.1 0.28 11.8 0.1 1.7 1 0 0 1 1 1 0 Bacterial cadherin-like domain Ge1_WD40 PF16529.5 ORY47836.1 - 0.24 10.3 0.2 33 3.3 0.0 3.1 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TRAM_LAG1_CLN8 PF03798.16 ORY47837.1 - 2.4e-36 125.4 22.0 2.7e-36 125.2 22.0 1.0 1 0 0 1 1 1 1 TLC domain zf-C2H2 PF00096.26 ORY47838.1 - 1.8e-09 37.5 21.5 0.0014 19.0 0.1 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY47838.1 - 1.2e-07 31.8 26.1 0.00039 20.7 1.0 4.7 4 1 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY47838.1 - 0.022 15.6 25.8 0.83 10.7 0.2 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORY47838.1 - 0.023 14.8 10.6 0.05 13.8 0.0 2.3 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_8 PF15909.5 ORY47838.1 - 0.032 14.5 0.7 0.032 14.5 0.7 3.0 1 1 2 3 3 3 0 C2H2-type zinc ribbon LRR_8 PF13855.6 ORY47839.1 - 6.8e-10 38.6 27.6 8e-07 28.7 8.5 4.9 4 2 2 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 ORY47839.1 - 2.8e-09 37.1 22.4 1.9e-05 24.9 3.0 6.0 2 2 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY47839.1 - 5.7e-05 23.1 19.3 0.083 13.5 0.1 6.5 6 0 0 6 6 6 3 Leucine Rich Repeat Ammonium_transp PF00909.21 ORY47840.1 - 1.2e-90 304.1 36.2 6.3e-90 301.7 36.2 1.8 1 1 0 1 1 1 1 Ammonium Transporter Family LRR_4 PF12799.7 ORY47841.1 - 2.5e-07 30.9 12.3 0.084 13.3 1.5 4.8 2 2 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY47841.1 - 3e-06 26.9 9.0 0.84 9.5 1.8 4.2 3 1 0 4 4 4 3 Leucine rich repeat F-box PF00646.33 ORY47841.1 - 0.00022 21.0 0.1 0.00072 19.4 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY47841.1 - 0.021 14.7 0.1 0.055 13.4 0.1 1.7 1 0 0 1 1 1 0 F-box-like LRR_1 PF00560.33 ORY47841.1 - 0.04 14.5 14.9 16 6.5 0.1 6.9 6 1 0 6 6 6 0 Leucine Rich Repeat PQ-loop PF04193.14 ORY47843.1 - 8.6e-09 35.0 0.6 1.3e-08 34.4 0.2 1.5 1 1 0 1 1 1 1 PQ loop repeat MtN3_slv PF03083.16 ORY47843.1 - 0.037 14.1 0.8 0.069 13.2 0.8 1.4 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange Utp12 PF04003.12 ORY47844.1 - 1e-24 86.9 2.3 1e-24 86.9 2.3 1.8 2 0 0 2 2 2 1 Dip2/Utp12 Family Med25_SD1 PF11235.8 ORY47844.1 - 0.045 14.1 1.9 0.11 12.8 0.6 2.0 1 1 0 2 2 2 0 Mediator complex subunit 25 synapsin 1 UTP15_C PF09384.10 ORY47844.1 - 0.079 12.6 0.2 0.14 11.9 0.2 1.5 1 0 0 1 1 1 0 UTP15 C terminal NOA36 PF06524.12 ORY47844.1 - 3.6 6.8 13.0 4.9 6.4 13.0 1.2 1 0 0 1 1 1 0 NOA36 protein cNMP_binding PF00027.29 ORY47846.1 - 9.7e-19 67.2 0.0 2.2e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 ORY47846.1 - 2.2e-06 27.1 14.2 3.5e-06 26.4 14.2 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 ORY47847.1 - 1.1e-20 73.4 0.0 2.7e-18 65.8 0.0 2.6 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Ion_trans PF00520.31 ORY47848.1 - 0.037 13.3 5.1 0.054 12.7 5.1 1.2 1 0 0 1 1 1 0 Ion transport protein SR-25 PF10500.9 ORY47849.1 - 3e-27 95.7 37.8 4.1e-22 78.9 1.1 2.1 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein SOBP PF15279.6 ORY47849.1 - 0.037 14.6 16.9 0.045 14.4 16.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CDC45 PF02724.14 ORY47849.1 - 0.18 10.1 12.8 0.2 9.9 12.8 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 ORY47849.1 - 0.19 11.8 20.7 0.24 11.5 20.7 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Apt1 PF10351.9 ORY47849.1 - 0.4 9.5 13.1 0.43 9.4 13.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Dsh_C PF12316.8 ORY47849.1 - 1.1 9.6 21.4 1.6 9.1 21.4 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Peptidase_S64 PF08192.11 ORY47849.1 - 1.5 7.2 9.5 1.3 7.5 9.5 1.2 1 0 0 1 1 1 0 Peptidase family S64 Macoilin PF09726.9 ORY47849.1 - 2.7 6.5 12.9 2.8 6.4 12.9 1.1 1 0 0 1 1 1 0 Macoilin family SLC12 PF03522.15 ORY47849.1 - 3 6.8 9.9 3.1 6.7 9.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Ammonium_transp PF00909.21 ORY47850.1 - 1.3e-106 356.6 32.9 1.5e-106 356.5 32.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family zf-C2H2 PF00096.26 ORY47852.1 - 2.2e-17 62.5 30.4 0.00093 19.5 0.7 5.5 6 0 0 6 6 5 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY47852.1 - 3.7e-16 58.7 20.8 6.1e-08 32.8 1.3 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY47852.1 - 1.8e-15 56.3 26.0 0.00083 20.0 1.4 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger FOXP-CC PF16159.5 ORY47852.1 - 1.1e-05 26.0 2.5 5.1 7.8 0.1 4.2 3 1 1 4 4 4 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 ORY47852.1 - 0.00047 20.4 9.8 0.19 12.0 0.0 5.0 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 ORY47852.1 - 0.01 16.5 10.6 0.47 11.2 1.8 2.9 3 0 0 3 3 3 0 TRAF-type zinc finger zf-C2H2_aberr PF17017.5 ORY47852.1 - 0.021 15.0 10.7 0.74 9.9 0.1 3.9 1 1 3 4 4 4 0 Aberrant zinc-finger Spt46 PF17734.1 ORY47852.1 - 0.061 13.1 2.7 4 7.2 0.4 2.2 1 1 1 2 2 2 0 Spermatogenesis-associated protein 46 DUF3268 PF11672.8 ORY47852.1 - 0.47 10.8 4.2 11 6.4 0.4 2.3 2 0 0 2 2 2 0 zinc-finger-containing domain zf-met PF12874.7 ORY47852.1 - 0.47 10.9 14.8 0.82 10.2 0.5 5.1 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 ORY47852.1 - 2 8.2 15.7 1.6 8.6 0.4 4.5 4 0 0 4 4 4 0 C2H2-type zinc-finger domain CpXC PF14353.6 ORY47852.1 - 2 8.5 4.2 2.5 8.2 0.1 2.3 2 1 0 2 2 2 0 CpXC protein zf-C2H2_11 PF16622.5 ORY47852.1 - 2.6 7.9 8.5 11 5.9 0.3 3.7 4 0 0 4 4 4 0 zinc-finger C2H2-type GSIII_N PF12437.8 ORY47853.1 - 2.8e-61 205.9 0.0 4.1e-61 205.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 ORY47853.1 - 3e-39 133.5 0.0 5.7e-39 132.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 ORY47853.1 - 6.6e-21 74.7 0.0 1.3e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain zf-H2C2_2 PF13465.6 ORY47854.1 - 1.8e-12 47.0 12.1 8.7e-05 22.8 0.4 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORY47854.1 - 3.1e-10 39.9 28.7 0.0063 16.9 1.3 4.8 5 0 0 5 5 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY47854.1 - 5.1e-10 39.3 19.6 0.0081 16.9 1.1 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY47854.1 - 0.00071 19.5 14.1 1.8 8.6 0.3 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger FOXP-CC PF16159.5 ORY47854.1 - 0.0011 19.5 6.6 0.17 12.6 0.3 3.5 1 1 2 3 3 3 1 FOXP coiled-coil domain zf-C2H2_11 PF16622.5 ORY47854.1 - 0.0038 17.0 4.0 0.033 13.9 0.1 3.1 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 ORY47854.1 - 0.017 15.4 9.0 1.3 9.4 0.1 3.8 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORY47854.1 - 0.02 15.2 11.3 0.021 15.1 3.3 2.8 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 ORY47854.1 - 0.093 12.7 8.1 0.35 10.8 0.1 3.1 3 1 0 3 3 2 0 zinc-finger of a C2HC-type Med27 PF11571.8 ORY47854.1 - 0.19 12.1 5.0 8.7 6.8 0.4 3.3 3 0 0 3 3 3 0 Mediator complex subunit 27 zinc_ribbon_15 PF17032.5 ORY47854.1 - 3.3 8.5 8.3 1.6e+02 3.2 0.4 3.3 2 1 1 3 3 3 0 zinc-ribbon family zf-met PF12874.7 ORY47854.1 - 3.6 8.1 10.2 10 6.7 0.3 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.6 ORY47855.1 - 5.5e-29 99.3 39.4 5.3e-08 32.9 0.1 8.2 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2 PF00096.26 ORY47855.1 - 2.2e-25 87.7 47.0 0.00076 19.8 1.0 8.8 8 0 0 8 8 8 8 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY47855.1 - 7.8e-19 66.7 45.6 0.0072 17.1 0.4 8.7 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY47855.1 - 2.3e-13 50.1 18.0 0.0054 17.0 0.1 6.5 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY47855.1 - 6.2e-06 26.1 27.5 0.046 13.7 0.4 6.8 6 0 0 6 6 6 3 C2H2-type zinc finger zf-met PF12874.7 ORY47855.1 - 0.0004 20.7 22.3 0.037 14.4 0.2 6.4 6 0 0 6 6 6 3 Zinc-finger of C2H2 type FOXP-CC PF16159.5 ORY47855.1 - 0.00055 20.5 20.4 0.74 10.5 0.1 6.2 4 2 2 6 6 6 2 FOXP coiled-coil domain TRAF6_Z2 PF18048.1 ORY47855.1 - 0.0052 16.8 11.8 3.9 7.7 0.0 6.1 6 0 0 6 6 6 2 TNF receptor-associated factor 6 zinc finger 2 zf-H2C2_5 PF13909.6 ORY47855.1 - 0.011 15.5 2.2 0.011 15.5 2.2 7.3 7 0 0 7 7 7 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 ORY47855.1 - 0.039 13.7 11.4 0.067 13.0 0.0 5.4 6 0 0 6 6 6 0 zinc-finger C2H2-type ROS_MUCR PF05443.11 ORY47855.1 - 0.3 11.1 2.3 3.4 7.7 0.3 2.5 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein zf-CGNR PF11706.8 ORY47855.1 - 1 9.3 4.5 22 5.0 0.1 3.6 3 0 0 3 3 3 0 CGNR zinc finger CpXC PF14353.6 ORY47855.1 - 1.1 9.4 9.0 18 5.4 0.7 4.4 5 0 0 5 5 5 0 CpXC protein zf-LYAR PF08790.11 ORY47855.1 - 1.2 9.1 3.5 19 5.3 0.0 3.9 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf_UBZ PF18439.1 ORY47855.1 - 1.9 8.2 9.4 9.5 5.9 0.2 4.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C2H2 PF00096.26 ORY47856.1 - 2.3e-12 46.7 12.6 0.00064 20.0 1.0 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY47856.1 - 6e-11 42.3 4.9 2.1e-06 27.9 0.3 3.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY47856.1 - 6.4e-09 35.9 10.8 0.00037 21.1 0.5 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY47856.1 - 0.0021 18.3 2.0 0.0022 18.2 0.4 1.7 1 1 1 2 2 2 1 C2H2-type zinc ribbon FOXP-CC PF16159.5 ORY47856.1 - 0.0023 18.5 2.1 0.86 10.3 0.1 2.4 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 ORY47856.1 - 0.015 15.5 0.1 0.15 12.3 0.2 2.6 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF3268 PF11672.8 ORY47856.1 - 0.025 14.9 2.2 0.025 14.9 2.2 1.5 2 0 0 2 2 2 0 zinc-finger-containing domain zf-C2HE PF16278.5 ORY47856.1 - 0.043 14.3 3.3 12 6.5 0.0 3.0 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_6 PF13912.6 ORY47856.1 - 0.29 11.2 0.2 0.29 11.2 0.2 3.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 ORY47856.1 - 3.6 7.4 22.1 2.3 8.1 1.6 4.1 4 1 0 4 4 4 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 ORY47857.1 - 2.9e-14 52.7 7.8 1.2e-08 35.0 2.8 4.7 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORY47857.1 - 4.1e-13 49.0 21.0 0.00039 20.7 1.2 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY47857.1 - 1.6e-09 37.7 20.0 0.0009 19.9 0.5 4.2 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY47857.1 - 4.1e-06 26.9 6.5 0.068 13.5 0.1 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORY47857.1 - 0.013 15.7 6.8 0.11 12.8 1.1 2.5 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 ORY47857.1 - 0.039 14.0 11.2 1 9.4 0.1 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.7 ORY47857.1 - 0.042 14.2 8.2 6.4 7.3 0.2 3.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 ORY47857.1 - 0.14 12.0 8.9 1.2 8.9 1.6 4.0 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 ORY47858.1 - 3.3e-15 55.7 11.2 5.5e-06 26.6 0.1 4.2 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORY47858.1 - 4.7e-10 39.4 22.2 0.0018 18.6 0.3 4.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY47858.1 - 1.6e-08 34.7 16.1 0.04 14.8 0.1 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger FOXP-CC PF16159.5 ORY47858.1 - 0.0005 20.6 6.5 0.84 10.3 0.1 4.1 3 1 1 4 4 4 2 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 ORY47858.1 - 0.00076 19.7 0.5 0.23 11.8 0.1 3.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY47858.1 - 0.0022 17.9 10.4 3.7 7.7 0.0 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY47858.1 - 0.04 14.2 5.5 0.083 13.2 0.5 2.7 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-met PF12874.7 ORY47858.1 - 0.075 13.5 1.2 15 6.1 0.4 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 ORY47859.1 - 9.3e-25 85.7 36.4 0.00022 21.5 0.7 7.6 7 0 0 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY47859.1 - 5.9e-17 60.9 35.9 0.0019 18.9 0.7 7.4 7 0 0 7 7 7 5 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY47859.1 - 1e-16 60.5 32.4 6.3e-05 23.2 0.1 7.6 8 0 0 8 8 7 4 Zinc-finger double domain zf-C2H2_8 PF15909.5 ORY47859.1 - 1.7e-08 34.7 16.8 0.00077 19.7 1.6 3.9 2 1 2 4 4 4 2 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 ORY47859.1 - 4.7e-05 23.5 16.2 0.34 11.2 0.9 5.5 5 1 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY47859.1 - 6.7e-05 23.1 11.3 0.19 12.2 1.1 5.3 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY47859.1 - 0.0002 21.2 35.7 0.02 14.9 1.7 6.8 7 0 0 7 7 7 3 C2H2-type zinc finger IBR PF01485.21 ORY47859.1 - 0.0027 17.9 18.2 0.056 13.7 1.1 4.1 2 1 2 4 4 4 2 IBR domain, a half RING-finger domain zf-C2H2_11 PF16622.5 ORY47859.1 - 0.023 14.4 10.4 0.98 9.2 0.0 4.2 4 0 0 4 4 3 0 zinc-finger C2H2-type zf-C2H2_7 PF15269.6 ORY47859.1 - 0.049 13.7 9.4 1.5 8.9 0.2 4.7 4 0 0 4 4 4 0 Zinc-finger FOXP-CC PF16159.5 ORY47859.1 - 0.091 13.4 15.2 4.5 8.0 0.5 4.8 4 1 0 4 4 4 0 FOXP coiled-coil domain Rep_fac-A_C PF08646.10 ORY47859.1 - 0.13 12.0 3.5 3.1 7.5 0.1 2.6 2 1 0 2 2 2 0 Replication factor-A C terminal domain C1_4 PF07975.12 ORY47859.1 - 0.34 11.2 10.9 1.3 9.3 0.1 3.4 3 0 0 3 3 3 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 ORY47859.1 - 0.36 11.0 20.7 2.6 8.2 0.7 4.6 3 1 1 4 4 4 0 Zinc ribbon domain zinc_ribbon_4 PF13717.6 ORY47859.1 - 0.53 10.2 4.5 39 4.3 0.1 3.8 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2_2 PF12756.7 ORY47859.1 - 0.54 10.6 21.0 0.4 11.0 0.4 4.6 3 2 3 6 6 5 0 C2H2 type zinc-finger (2 copies) zf-RING_7 PF02591.15 ORY47859.1 - 0.75 10.0 2.9 23 5.3 0.2 3.2 3 0 0 3 3 2 0 C4-type zinc ribbon domain CpXC PF14353.6 ORY47859.1 - 1.5 8.9 11.1 4.1 7.5 0.1 3.9 2 2 2 4 4 4 0 CpXC protein zf-C2H2_aberr PF17017.5 ORY47859.1 - 2.1 8.4 13.9 1.7 8.8 0.1 3.8 2 2 2 4 4 4 0 Aberrant zinc-finger C1_2 PF03107.16 ORY47859.1 - 7.4 7.0 17.4 2.7 8.4 2.9 4.2 3 2 0 3 3 2 0 C1 domain zf-Di19 PF05605.12 ORY47859.1 - 7.8 6.9 24.1 7.1 7.0 3.1 4.4 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_9 PF16293.5 ORY47859.1 - 8.1 6.4 6.4 14 5.6 0.1 3.6 5 0 0 5 5 4 0 C2H2 type zinc-finger (1 copy) zf-H2C2_2 PF13465.6 ORY47860.1 - 4.1e-08 33.3 9.0 6.6e-05 23.2 5.4 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY47860.1 - 6.3e-08 32.7 22.9 0.0074 16.7 5.5 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY47860.1 - 0.0001 22.8 24.7 0.0059 17.3 3.9 3.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY47860.1 - 0.0029 17.9 1.0 2.8 8.3 0.4 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 ORY47860.1 - 6.8 6.5 17.5 1.6 8.6 0.4 3.8 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.6 ORY47861.1 - 8.5e-16 57.6 18.9 2.1e-07 31.0 0.5 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORY47861.1 - 5.8e-10 39.1 25.9 0.00019 21.7 1.6 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY47861.1 - 3e-09 36.9 23.7 0.00063 20.4 0.7 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY47861.1 - 2.6e-05 24.4 4.1 0.0009 19.5 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORY47861.1 - 0.0069 16.7 3.2 0.0069 16.7 3.2 2.7 2 1 0 3 3 3 1 C2H2-type zinc ribbon zf-met PF12874.7 ORY47861.1 - 0.0098 16.3 8.5 0.019 15.4 0.8 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 ORY47861.1 - 0.037 13.8 1.5 4.5 7.1 0.2 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 ORY47861.1 - 0.06 13.4 4.8 0.79 9.8 0.3 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.12 ORY47861.1 - 0.11 12.8 7.2 9 6.7 0.0 2.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding CMD PF02627.20 ORY47861.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family Zn-C2H2_12 PF18112.1 ORY47861.1 - 0.4 11.2 2.4 8.7 6.9 0.2 3.5 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain zf_PR_Knuckle PF18445.1 ORY47861.1 - 2.5 8.0 7.1 0.36 10.7 0.7 2.7 3 0 0 3 3 3 0 PR zinc knuckle motif zf-H2C2_5 PF13909.6 ORY47861.1 - 4.4 7.1 15.8 0.13 12.0 3.2 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Stm1_N PF09598.10 ORY47862.1 - 0.017 16.0 11.5 0.017 16.0 11.5 3.7 2 2 2 4 4 4 0 Stm1 DUF410 PF04190.13 ORY47862.1 - 0.094 12.5 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF410) TTL PF03133.15 ORY47863.1 - 4.3e-77 259.1 4.5 8e-77 258.3 1.0 2.7 2 1 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 ORY47863.1 - 6.9e-08 32.1 0.1 0.00051 19.4 0.0 3.3 3 1 0 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 ORY47863.1 - 0.00012 21.4 0.0 0.042 13.1 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 ORY47863.1 - 0.00072 19.6 0.0 0.004 17.2 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain Mannosyl_trans3 PF11051.8 ORY47864.1 - 2.5e-39 135.3 0.0 6.7e-39 133.9 0.0 1.6 1 1 0 1 1 1 1 Mannosyltransferase putative GPI-anchored PF10342.9 ORY47865.1 - 0.022 15.5 2.9 0.044 14.5 1.0 2.4 1 1 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mucin PF01456.17 ORY47865.1 - 0.09 12.8 10.3 0.16 12.0 10.3 1.5 1 1 0 1 1 1 0 Mucin-like glycoprotein F-box_4 PF15966.5 ORY47867.1 - 0.039 13.9 0.1 0.081 12.8 0.1 1.5 1 0 0 1 1 1 0 F-box F-box PF00646.33 ORY47868.1 - 1.4e-05 24.9 0.4 3.2e-05 23.7 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY47868.1 - 7.8e-05 22.5 0.5 0.00028 20.7 0.1 2.1 2 0 0 2 2 2 1 F-box-like B9-C2 PF07162.11 ORY47869.1 - 4.3e-48 163.7 0.0 5.2e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Ammonium_transp PF00909.21 ORY47870.1 - 4.5e-103 345.0 31.6 5.1e-103 344.8 31.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family PhoR PF11808.8 ORY47870.1 - 5.4 7.5 0.0 5.4 7.5 0.0 3.8 4 0 0 4 4 4 0 Phosphate regulon sensor protein PhoR Nt_Gln_amidase PF09764.9 ORY47872.1 - 7.8e-39 133.2 0.0 7.5e-26 90.9 0.0 2.0 1 1 1 2 2 2 2 N-terminal glutamine amidase DUF953 PF06110.11 ORY47873.1 - 7.7e-19 67.5 0.0 9.2e-19 67.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 ORY47873.1 - 0.0083 15.9 0.0 0.015 15.1 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin Fez1 PF06818.15 ORY47874.1 - 0.0041 17.6 11.6 0.0041 17.6 11.6 7.2 2 1 3 5 5 5 1 Fez1 DUF4201 PF13870.6 ORY47874.1 - 0.0056 16.4 0.7 0.0056 16.4 0.7 9.1 6 2 3 10 10 10 3 Domain of unknown function (DUF4201) ADIP PF11559.8 ORY47874.1 - 0.012 15.6 5.7 0.012 15.6 5.7 10.3 7 2 5 12 12 12 0 Afadin- and alpha -actinin-Binding UPF0052 PF01933.18 ORY47875.1 - 2e-41 142.1 0.0 4.7e-41 140.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 7TM_GPCR_Sra PF02117.16 ORY47875.1 - 0.15 10.9 4.3 0.24 10.2 4.3 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sra ORC6 PF05460.13 ORY47875.1 - 0.18 11.1 4.4 0.3 10.3 4.4 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) 3HCDH PF00725.22 ORY47876.1 - 0.12 13.0 0.0 0.25 12.0 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Ammonium_transp PF00909.21 ORY47878.1 - 4e-82 276.1 22.3 5.1e-82 275.7 22.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Ammonium_transp PF00909.21 ORY47879.1 - 9.6e-70 235.3 40.3 4.4e-66 223.2 40.3 3.6 1 1 0 1 1 1 1 Ammonium Transporter Family Fungal_trans PF04082.18 ORY47880.1 - 1.2e-05 24.5 0.2 2.1e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CK2S PF15011.6 ORY47880.1 - 0.083 12.8 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 Casein Kinase 2 substrate Zn_clus PF00172.18 ORY47881.1 - 0.00012 22.1 8.5 0.00021 21.3 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY47881.1 - 0.0023 17.0 0.5 0.0066 15.5 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY47882.1 - 1e-05 25.5 10.5 1.5e-05 25.0 10.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_kinase PF01513.21 ORY47884.1 - 6.8e-64 215.9 0.0 2.4e-62 210.8 0.0 2.0 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 ORY47884.1 - 0.097 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain TPALS PF18178.1 ORY47884.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 TIR- and PNP-associating SLOG family TMEM43 PF07787.12 ORY47885.1 - 5.7e-29 101.3 0.7 8.8e-29 100.6 0.7 1.3 1 0 0 1 1 1 1 Transmembrane protein 43 Abhydrolase_9_N PF15420.6 ORY47885.1 - 3.6 7.6 11.0 12 5.8 0.3 2.6 2 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Fungal_trans PF04082.18 ORY47886.1 - 0.0008 18.5 0.3 0.0019 17.3 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY47886.1 - 0.82 9.9 9.6 1.4 9.1 9.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_8 PF13855.6 ORY47887.1 - 6.2e-16 57.9 31.9 3.5e-06 26.7 5.7 3.5 2 1 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY47887.1 - 5.7e-11 42.5 31.4 0.0029 18.0 1.7 4.6 2 1 1 4 4 4 4 Leucine Rich repeats (2 copies) F-box PF00646.33 ORY47887.1 - 5.4e-06 26.1 0.8 1.9e-05 24.4 0.8 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY47887.1 - 7.5e-05 22.5 0.5 0.00018 21.3 0.5 1.7 1 0 0 1 1 1 1 F-box-like Fungal_trans PF04082.18 ORY47887.1 - 8.1e-05 21.8 0.3 0.00019 20.6 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY47887.1 - 0.00035 20.6 9.8 0.00063 19.8 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_1 PF00560.33 ORY47887.1 - 0.018 15.5 27.4 1.5 9.7 2.2 7.1 5 2 0 5 5 5 0 Leucine Rich Repeat YchF-GTPase_C PF06071.13 ORY47888.1 - 5.6e-34 116.2 0.5 1.6e-33 114.7 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 ORY47888.1 - 1.2e-19 70.5 0.1 5.1e-19 68.4 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY47888.1 - 2e-06 27.4 0.0 4.1e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 ORY47888.1 - 0.025 14.6 0.3 0.12 12.5 0.0 2.3 2 1 0 2 2 2 0 TGS domain Isochorismatase PF00857.20 ORY47890.1 - 2.3e-11 44.2 0.0 1e-09 38.8 0.0 2.8 2 1 0 2 2 2 1 Isochorismatase family Motile_Sperm PF00635.26 ORY47891.1 - 6.8e-14 51.6 0.7 5.2e-13 48.8 0.6 2.2 2 1 0 2 2 2 1 MSP (Major sperm protein) domain PapD_N PF00345.20 ORY47891.1 - 0.029 14.3 0.5 0.058 13.3 0.5 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain fn3_6 PF17766.1 ORY47891.1 - 0.033 14.4 0.3 5.8 7.2 0.1 2.2 1 1 1 2 2 2 0 Fibronectin type-III domain WAP PF00095.21 ORY47892.1 - 0.00014 22.2 61.1 0.092 13.2 4.9 6.1 5 1 0 5 5 5 5 WAP-type (Whey Acidic Protein) 'four-disulfide core' Dickkopf_N PF04706.12 ORY47892.1 - 0.027 15.0 47.7 0.097 13.2 0.7 5.9 6 0 0 6 6 6 0 Dickkopf N-terminal cysteine-rich region NAD_binding_2 PF03446.15 ORY47893.1 - 1.5e-38 132.4 2.0 2.4e-38 131.8 2.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 ORY47893.1 - 1.1e-33 116.1 0.1 2.6e-33 114.9 0.0 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 ORY47893.1 - 0.0017 17.8 0.1 0.0048 16.3 0.0 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 ORY47893.1 - 0.0017 18.9 0.0 0.0052 17.3 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 ORY47893.1 - 0.028 13.4 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Inhibitor_I67 PF11405.8 ORY47893.1 - 0.17 12.1 0.1 0.32 11.3 0.1 1.3 1 0 0 1 1 1 0 Bromelain inhibitor VI Peptidase_C23 PF05379.11 ORY47894.1 - 0.064 13.4 0.2 0.15 12.2 0.2 1.7 1 1 0 1 1 1 0 Carlavirus endopeptidase Coilin_N PF15862.5 ORY47896.1 - 4.2e-05 23.4 6.7 4.2e-05 23.4 6.7 4.7 1 1 1 2 2 2 1 Coilin N-terminus DUF936 PF06075.12 ORY47896.1 - 6.7 5.5 51.9 9.1 5.1 51.9 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Sel1 PF08238.12 ORY47897.1 - 4.1e-125 405.4 75.8 5.4e-11 42.8 0.3 18.5 18 1 0 18 18 18 17 Sel1 repeat TIR_2 PF13676.6 ORY47897.1 - 5.1e-31 107.7 0.0 1.9e-14 54.3 0.0 2.5 2 0 0 2 2 2 2 TIR domain TPR_12 PF13424.6 ORY47897.1 - 7.1e-06 26.2 23.3 0.045 14.1 0.0 9.1 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY47897.1 - 9.3e-06 25.3 17.9 0.44 10.7 0.0 10.1 11 1 0 11 11 11 1 Tetratricopeptide repeat TIR PF01582.20 ORY47897.1 - 1.5e-05 24.8 0.1 0.061 13.1 0.0 2.3 2 0 0 2 2 2 2 TIR domain TPR_17 PF13431.6 ORY47897.1 - 0.0056 17.0 17.8 4.8 7.8 0.0 8.9 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY47897.1 - 0.0089 15.8 0.0 0.0089 15.8 0.0 12.6 15 0 0 15 15 15 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY47897.1 - 0.04 14.1 0.0 0.04 14.1 0.0 9.6 13 1 0 13 13 11 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY47897.1 - 0.047 13.8 0.0 0.047 13.8 0.0 11.8 16 0 0 16 16 13 0 Tetratricopeptide repeat DUF1863 PF08937.11 ORY47897.1 - 0.14 12.5 0.1 4 7.7 0.0 2.4 2 0 0 2 2 2 0 MTH538 TIR-like domain (DUF1863) Chol_subst-bind PF09129.11 ORY47897.1 - 0.77 8.7 6.2 0.72 8.7 0.3 3.4 4 1 0 4 4 4 0 Cholesterol oxidase, substrate-binding TPR_10 PF13374.6 ORY47897.1 - 1.1 9.3 0.0 1.1 9.3 0.0 8.2 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY47897.1 - 2.2 9.0 0.0 2.2 9.0 0.0 6.8 6 2 2 9 9 9 0 Tetratricopeptide repeat 7tm_3 PF00003.22 ORY47898.1 - 1.3e-21 77.4 16.4 1.3e-21 77.4 16.4 1.8 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR PBP_like_2 PF12849.7 ORY47898.1 - 8.4e-18 65.0 4.4 1.6e-17 64.1 4.4 1.3 1 0 0 1 1 1 1 PBP superfamily domain SBP_bac_1 PF01547.25 ORY47898.1 - 1.6e-05 25.0 0.2 2.6e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein DUF4054 PF13262.6 ORY47899.1 - 0.096 12.7 0.2 21 5.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4054) Dala_Dala_lig_C PF07478.13 ORY47899.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus RT_RNaseH_2 PF17919.1 ORY47900.1 - 0.00023 21.1 0.0 0.00082 19.4 0.0 1.9 1 1 1 2 2 2 1 RNase H-like domain found in reverse transcriptase YebO PF13974.6 ORY47901.1 - 0.077 13.1 6.2 0.2 11.8 6.2 1.6 1 0 0 1 1 1 0 YebO-like protein Arm PF00514.23 ORY47902.1 - 1.5e-31 107.4 10.2 8.1e-10 38.4 0.1 8.3 7 1 0 7 7 7 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 ORY47902.1 - 9.1e-12 45.2 0.5 1e-07 32.3 0.0 5.4 4 2 2 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.6 ORY47902.1 - 2.7e-10 40.5 0.3 0.0021 18.4 0.0 5.3 3 2 3 6 6 6 2 HEAT repeats HEAT PF02985.22 ORY47902.1 - 2.5e-08 33.5 3.9 0.00034 20.6 0.0 5.1 5 0 0 5 5 5 1 HEAT repeat Adaptin_N PF01602.20 ORY47902.1 - 6.5e-05 21.7 0.4 0.077 11.5 0.2 2.4 2 1 0 2 2 2 2 Adaptin N terminal region HEAT_PBS PF03130.16 ORY47902.1 - 0.00044 20.7 2.5 0.23 12.2 0.0 3.8 4 0 0 4 4 3 1 PBS lyase HEAT-like repeat RICTOR_V PF14668.6 ORY47902.1 - 0.01 16.0 0.5 1.7 8.9 0.1 3.5 2 1 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.13 ORY47902.1 - 0.013 14.9 0.0 2.9 7.3 0.1 2.8 2 1 1 3 3 3 0 Armadillo-like V-ATPase_H_C PF11698.8 ORY47902.1 - 0.022 14.9 0.1 1.4 9.1 0.1 3.3 4 0 0 4 4 4 0 V-ATPase subunit H NUC173 PF08161.12 ORY47902.1 - 0.033 13.9 0.1 0.84 9.3 0.0 2.3 2 0 0 2 2 2 0 NUC173 domain NopRA1 PF16201.5 ORY47902.1 - 0.034 13.7 0.0 13 5.3 0.0 3.3 2 2 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 Nipped-B_C PF12830.7 ORY47902.1 - 0.063 13.2 0.6 1.8 8.4 0.0 2.7 2 1 1 3 3 3 0 Sister chromatid cohesion C-terminus Proteasom_PSMB PF10508.9 ORY47902.1 - 0.15 10.5 1.1 2.9 6.3 0.5 2.4 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit WD40 PF00400.32 ORY47903.1 - 3e-49 163.9 33.5 3.2e-07 30.9 1.3 10.8 10 0 0 10 10 10 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY47903.1 - 3.6e-14 52.8 9.8 0.23 11.8 0.0 8.7 2 1 5 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain TIR_2 PF13676.6 ORY47903.1 - 2.8e-13 50.5 0.0 1.3e-12 48.3 0.0 2.3 1 0 0 1 1 1 1 TIR domain WD40_like PF17005.5 ORY47903.1 - 2e-09 37.2 0.7 0.0009 18.7 0.0 3.2 2 1 1 3 3 3 2 WD40-like domain Nup160 PF11715.8 ORY47903.1 - 1.3e-06 27.4 6.4 2.2 6.8 0.0 6.6 1 1 4 7 7 7 2 Nucleoporin Nup120/160 NACHT PF05729.12 ORY47903.1 - 1.1e-05 25.5 0.1 3.9e-05 23.6 0.1 2.0 1 1 0 1 1 1 1 NACHT domain PALB2_WD40 PF16756.5 ORY47903.1 - 0.001 18.1 3.4 0.29 10.0 0.2 3.9 4 0 0 4 4 4 1 Partner and localizer of BRCA2 WD40 domain Ge1_WD40 PF16529.5 ORY47903.1 - 0.0019 17.2 7.5 0.54 9.2 0.2 5.2 3 1 1 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein AAA_16 PF13191.6 ORY47903.1 - 0.0019 18.6 0.0 0.0049 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 ORY47903.1 - 0.035 13.3 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 ORY47903.1 - 0.073 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PQQ_3 PF13570.6 ORY47903.1 - 0.43 11.1 1.5 16 6.2 0.0 4.1 3 1 1 4 4 4 0 PQQ-like domain LRR_8 PF13855.6 ORY47904.1 - 1.5e-18 66.3 25.7 4.2e-06 26.4 3.5 4.8 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY47904.1 - 4.8e-12 45.9 27.0 0.0026 18.1 3.6 6.6 3 1 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY47904.1 - 2e-05 24.5 25.9 3.2 8.6 0.1 8.9 9 1 0 9 9 9 3 Leucine Rich Repeat F-box-like PF12937.7 ORY47904.1 - 0.0058 16.5 0.7 0.023 14.6 0.5 2.1 2 0 0 2 2 2 1 F-box-like LRR_9 PF14580.6 ORY47904.1 - 0.007 15.9 3.5 1.5 8.3 0.6 2.4 2 1 0 2 2 2 2 Leucine-rich repeat F-box PF00646.33 ORY47904.1 - 0.069 13.0 0.2 0.28 11.1 0.2 2.0 1 0 0 1 1 1 0 F-box domain LRR_6 PF13516.6 ORY47904.1 - 1.1 9.5 17.0 4.2 7.7 0.1 5.7 6 0 0 6 6 6 0 Leucine Rich repeat YhhN PF07947.14 ORY47905.1 - 1.9e-38 131.9 5.8 2.5e-38 131.6 5.8 1.2 1 0 0 1 1 1 1 YhhN family Acetyltransf_2 PF00797.17 ORY47906.1 - 5e-33 114.9 0.1 8.5e-32 110.8 0.1 2.0 1 1 0 1 1 1 1 N-acetyltransferase SHS2_Rpb7-N PF03876.17 ORY47908.1 - 1.3e-12 47.9 0.0 2.3e-12 47.1 0.0 1.4 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 ORY47908.1 - 1e-09 38.7 0.0 1.5e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 S1 PF00575.23 ORY47908.1 - 0.0064 16.8 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain Lipase_3 PF01764.25 ORY47910.1 - 9e-16 58.0 0.0 1.4e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) NKWYS PF10364.9 ORY47910.1 - 0.027 14.6 0.1 0.074 13.2 0.1 1.7 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein Abhydrolase_6 PF12697.7 ORY47910.1 - 0.033 14.8 0.1 0.086 13.4 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2105 PF09878.9 ORY47910.1 - 0.1 12.3 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2105) CAP PF00188.26 ORY47911.1 - 1.2e-13 52.0 0.4 2.5e-13 51.0 0.4 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Dicty_REP PF05086.12 ORY47911.1 - 0.88 7.5 4.4 1.1 7.1 4.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein STAG PF08514.11 ORY47913.1 - 2.1e-19 69.5 0.9 1.3e-18 66.9 0.9 2.4 1 0 0 1 1 1 1 STAG domain RHH_6 PF16762.5 ORY47913.1 - 0.0041 17.7 2.5 0.21 12.2 0.4 3.3 2 0 0 2 2 2 1 Ribbon-helix-helix domain HEAT PF02985.22 ORY47913.1 - 0.093 13.0 0.1 1e+02 3.6 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat V-SNARE PF05008.15 ORY47914.1 - 4.5e-17 62.2 1.2 4.5e-17 62.2 1.2 2.0 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 ORY47914.1 - 2.1e-12 47.1 2.6 2.1e-12 47.1 2.6 2.8 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 ORY47914.1 - 0.0019 18.0 1.9 0.0073 16.2 0.1 2.6 2 1 1 3 3 3 1 Sec20 WEMBL PF05701.11 ORY47914.1 - 0.0026 16.5 4.5 0.0039 16.0 4.5 1.3 1 1 0 1 1 1 1 Weak chloroplast movement under blue light YlqD PF11068.8 ORY47914.1 - 0.0058 17.0 4.5 0.0059 17.0 0.7 2.2 2 0 0 2 2 2 1 YlqD protein ThiD2 PF17792.1 ORY47914.1 - 0.018 15.5 0.6 0.018 15.5 0.6 1.9 2 1 0 2 2 2 0 ThiD2 family Prominin PF05478.11 ORY47914.1 - 0.15 10.0 1.3 0.22 9.4 1.3 1.2 1 1 0 1 1 1 0 Prominin Exonuc_VII_L PF02601.15 ORY47914.1 - 0.3 10.6 7.9 0.92 9.0 7.9 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit ARGLU PF15346.6 ORY47914.1 - 0.4 10.6 10.9 6.4 6.7 10.7 2.1 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 TcdB_N PF12918.7 ORY47914.1 - 1.1 9.5 3.8 3.6 8.0 0.3 2.4 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain DUF745 PF05335.13 ORY47914.1 - 3.5 7.3 4.9 3.2 7.4 1.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF745) FAM76 PF16046.5 ORY47914.1 - 6.1 6.1 7.1 4 6.7 2.4 1.8 1 1 0 2 2 2 0 FAM76 protein DUF515 PF04415.12 ORY47915.1 - 0.27 9.6 6.6 0.3 9.4 6.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Tir_receptor_C PF07489.11 ORY47915.1 - 0.33 10.9 8.7 0.45 10.4 8.7 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus SSP160 PF06933.11 ORY47915.1 - 0.35 9.0 12.9 0.55 8.4 12.9 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MGC-24 PF05283.11 ORY47915.1 - 4.3 7.8 13.3 5 7.6 13.3 1.3 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMEM154 PF15102.6 ORY47915.1 - 5.1 7.0 8.6 1.5 8.7 6.1 1.4 2 0 0 2 2 2 0 TMEM154 protein family zf-C2H2_4 PF13894.6 ORY47916.1 - 2.1e-05 24.9 0.7 0.38 11.7 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY47916.1 - 0.00014 22.1 0.6 0.11 13.0 0.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.7 ORY47916.1 - 0.14 12.6 0.0 0.85 10.1 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type CAP PF00188.26 ORY47920.1 - 0.0026 18.6 1.6 0.0026 18.6 1.6 2.6 2 2 0 2 2 2 1 Cysteine-rich secretory protein family MORN_2 PF07661.13 ORY47920.1 - 0.3 11.5 2.5 95 3.7 0.0 4.1 3 0 0 3 3 3 0 MORN repeat variant pXO2-34 PF17362.2 ORY47920.1 - 0.51 10.3 3.6 10 6.1 0.1 3.3 3 0 0 3 3 3 0 Family of unknown function Arabinose_trans PF04602.12 ORY47920.1 - 2.5 6.9 4.4 0.69 8.7 0.9 1.6 2 0 0 2 2 2 0 Mycobacterial cell wall arabinan synthesis protein CG-1 PF03859.16 ORY47920.1 - 2.6 7.9 9.3 16 5.3 0.5 3.3 1 1 2 3 3 3 0 CG-1 domain DUF347 PF03988.12 ORY47922.1 - 2e-32 111.1 34.7 1.5e-11 44.3 1.7 4.3 4 0 0 4 4 4 4 Repeat of Unknown Function (DUF347) bZIP_1 PF00170.21 ORY47923.1 - 3.1e-08 33.6 4.7 3.1e-08 33.6 4.7 2.5 2 1 1 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 ORY47923.1 - 4.6e-08 33.0 4.4 4.6e-08 33.0 4.4 2.1 2 0 0 2 2 2 1 Basic region leucine zipper CLZ PF16526.5 ORY47923.1 - 0.0044 17.3 2.3 0.0088 16.4 2.3 1.6 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4407 PF14362.6 ORY47923.1 - 0.025 14.0 1.6 0.033 13.5 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mpp10 PF04006.12 ORY47923.1 - 0.044 12.2 2.3 0.06 11.8 2.3 1.1 1 0 0 1 1 1 0 Mpp10 protein Atg14 PF10186.9 ORY47923.1 - 0.071 12.2 3.2 0.094 11.8 3.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4140 PF13600.6 ORY47923.1 - 0.073 13.5 1.7 0.16 12.4 1.7 1.7 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) HAUS-augmin3 PF14932.6 ORY47923.1 - 0.14 11.8 4.6 0.2 11.2 4.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4164 PF13747.6 ORY47923.1 - 0.18 12.1 7.9 0.38 11.1 7.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) EVC2_like PF12297.8 ORY47923.1 - 0.19 10.4 4.8 0.26 9.9 4.8 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein DUF4200 PF13863.6 ORY47923.1 - 1.8 9.0 7.0 0.7 10.3 2.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Striatin PF08232.12 ORY47923.1 - 4.1 8.0 8.7 0.18 12.4 0.8 2.3 2 1 1 3 3 3 0 Striatin family Hydrolase_3 PF08282.12 ORY47924.1 - 2.2e-51 175.1 0.0 2.5e-51 174.9 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 ORY47924.1 - 1.8e-13 50.6 0.0 2.1e-08 34.0 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 ORY47924.1 - 8.2e-10 39.3 0.0 0.0035 17.7 0.0 3.2 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY47924.1 - 9e-06 26.2 0.7 0.43 10.9 0.0 3.1 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 ORY47924.1 - 0.0014 18.7 0.0 0.0031 17.6 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY47924.1 - 0.0035 17.4 0.0 1.3 9.0 0.0 2.9 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase DUF3443 PF11925.8 ORY47924.1 - 0.032 13.1 0.0 0.05 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3443) Trehalose_PPase PF02358.16 ORY47924.1 - 0.081 12.0 0.0 2.8 7.0 0.0 2.7 2 1 0 3 3 3 0 Trehalose-phosphatase zf-C2H2_4 PF13894.6 ORY47926.1 - 7.7e-10 38.8 17.5 0.0016 19.1 0.5 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY47926.1 - 1.1e-05 25.6 20.0 0.001 19.4 1.1 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY47926.1 - 0.00088 19.6 19.5 0.0023 18.3 0.6 3.7 4 1 0 4 4 4 2 Zinc-finger double domain zf-Di19 PF05605.12 ORY47926.1 - 0.0011 19.2 6.4 0.51 10.7 3.3 2.3 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_9 PF14369.6 ORY47926.1 - 0.0016 18.7 0.6 1.4 9.3 0.1 2.4 2 0 0 2 2 2 2 zinc-ribbon BIR PF00653.21 ORY47926.1 - 0.0065 17.1 0.7 0.0065 17.1 0.7 1.8 1 1 1 2 2 2 1 Inhibitor of Apoptosis domain Zn-ribbon_8 PF09723.10 ORY47926.1 - 0.0088 16.1 3.0 1.8 8.7 0.5 2.4 2 0 0 2 2 2 2 Zinc ribbon domain zf-C2H2_jaz PF12171.8 ORY47926.1 - 0.0092 16.3 0.2 0.0092 16.3 0.2 3.9 4 1 0 4 4 4 1 Zinc-finger double-stranded RNA-binding TFIIE-A_C PF11521.8 ORY47926.1 - 0.0097 16.2 0.1 0.016 15.5 0.1 1.3 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha zf-C2H2_6 PF13912.6 ORY47926.1 - 0.069 13.2 18.1 0.17 11.9 2.8 3.6 3 1 0 3 3 3 0 C2H2-type zinc finger Ribosomal_L34e PF01199.18 ORY47926.1 - 0.069 13.5 3.6 3.5 8.0 0.4 2.1 1 1 1 2 2 2 0 Ribosomal protein L34e DUF1441 PF07278.11 ORY47926.1 - 0.17 11.8 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1441) zf-C2HC_2 PF13913.6 ORY47926.1 - 0.2 11.6 3.2 1.1 9.3 0.1 2.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-met PF12874.7 ORY47926.1 - 0.29 11.6 13.6 1.9 9.0 2.7 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 ORY47926.1 - 0.34 11.3 14.9 2.3 8.6 0.9 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) TRAF6_Z2 PF18048.1 ORY47926.1 - 0.38 10.9 4.7 1.4 9.1 1.2 3.1 3 1 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zf_UBZ PF18439.1 ORY47926.1 - 1.2 8.7 4.4 6.9 6.4 0.1 2.7 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2HE PF16278.5 ORY47926.1 - 3.4 8.2 7.5 8.4 6.9 0.3 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.26 ORY47927.1 - 1.3e-09 38.0 8.4 0.00018 21.8 0.9 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY47927.1 - 2.5e-09 37.2 7.1 0.00035 21.2 0.7 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY47927.1 - 4.3e-08 33.2 11.4 5.4e-07 29.7 0.7 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 ORY47927.1 - 5.8e-07 29.1 4.5 0.00053 19.7 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc-finger domain TRAF6_Z2 PF18048.1 ORY47927.1 - 0.0072 16.4 1.7 0.15 12.1 0.1 2.4 2 0 0 2 2 2 1 TNF receptor-associated factor 6 zinc finger 2 zf-met PF12874.7 ORY47927.1 - 0.028 14.8 1.5 3.4 8.2 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC PF01530.18 ORY47927.1 - 0.029 14.6 0.1 0.06 13.6 0.1 1.7 1 0 0 1 1 1 0 Zinc finger, C2HC type zf-C2H2_aberr PF17017.5 ORY47927.1 - 0.037 14.2 2.9 1.5 8.9 0.6 2.0 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 ORY47927.1 - 0.16 12.3 0.4 0.16 12.3 0.4 2.5 3 0 0 3 3 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ORY47927.1 - 0.22 11.9 4.1 5.3 7.5 0.2 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 ORY47927.1 - 0.6 10.2 5.8 1.8 8.7 0.1 2.5 2 1 0 2 2 2 0 C2H2-type zinc finger Mucin PF01456.17 ORY48019.1 - 0.36 10.8 40.7 0.24 11.4 37.7 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein zf-C2H2 PF00096.26 ORY48023.1 - 3.2e-05 24.1 2.9 0.0021 18.4 0.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY48023.1 - 0.00014 22.4 2.6 0.14 13.1 0.1 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY48023.1 - 0.6 10.6 4.9 0.82 10.2 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double domain EcKinase PF02958.20 ORY48024.1 - 3.4e-17 62.7 0.0 2.1e-12 47.0 0.0 2.1 2 0 0 2 2 2 2 Ecdysteroid kinase APH PF01636.23 ORY48024.1 - 1.8e-07 31.4 1.3 1.8e-07 31.3 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 ORY48024.1 - 0.00012 21.1 0.0 0.00026 20.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 ORY48024.1 - 0.0056 16.3 0.0 0.009 15.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF5566 PF17721.1 ORY48025.1 - 0.14 12.4 0.0 0.16 12.2 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5566) Paramecium_SA PF01508.16 ORY48025.1 - 0.22 12.0 5.6 0.37 11.3 5.6 1.3 1 0 0 1 1 1 0 Paramecium surface antigen domain IGFBP PF00219.18 ORY48025.1 - 2 9.1 12.1 42 4.9 12.4 2.3 1 1 0 1 1 1 0 Insulin-like growth factor binding protein Oxidored_FMN PF00724.20 ORY48026.1 - 3.1e-78 263.5 0.0 3.6e-78 263.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 ORY48026.1 - 0.0026 16.9 0.1 0.015 14.4 0.0 1.9 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) FAD_binding_3 PF01494.19 ORY48027.1 - 7.5e-17 61.6 0.1 4.2e-08 32.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 ORY48027.1 - 0.0074 15.6 0.3 0.015 14.6 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 ORY48027.1 - 0.045 12.8 0.0 0.26 10.3 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_2 PF07992.14 ORY48027.1 - 0.048 12.9 0.1 0.095 11.9 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ORY48027.1 - 0.11 11.8 0.1 0.17 11.1 0.1 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 ORY48027.1 - 0.18 10.6 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Hamartin PF04388.12 ORY48028.1 - 0.87 8.2 12.7 1 8.0 12.7 1.0 1 0 0 1 1 1 0 Hamartin protein zf-C2H2_4 PF13894.6 ORY48029.1 - 1.8e-06 28.3 4.7 0.089 13.7 0.0 3.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY48029.1 - 3.4e-05 24.1 4.5 0.15 12.6 0.0 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY48029.1 - 0.0017 18.7 3.1 0.14 12.6 0.1 2.9 2 0 0 2 2 2 2 Zinc-finger double domain Phage_BR0599 PF09356.10 ORY48031.1 - 0.091 13.1 1.8 0.12 12.7 0.3 2.0 2 0 0 2 2 2 0 Phage conserved hypothetical protein BR0599 VIR_N PF15912.5 ORY48031.1 - 0.1 12.2 0.3 0.28 10.8 0.1 1.7 2 0 0 2 2 2 0 Virilizer, N-terminal Dickkopf_N PF04706.12 ORY48031.1 - 0.18 12.3 2.0 4.1 8.0 0.0 3.6 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region DUF4841 PF16129.5 ORY48031.1 - 0.32 11.3 3.7 51 4.2 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4841) FCSD-flav_bind PF09242.11 ORY48031.1 - 0.9 9.9 8.2 3.5 8.0 0.3 3.3 4 0 0 4 4 4 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding zf-C2H2_4 PF13894.6 ORY48032.1 - 2.6e-09 37.1 4.8 0.00035 21.2 2.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY48032.1 - 6e-06 26.4 4.0 0.011 16.2 0.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY48032.1 - 3.8e-05 23.9 11.4 0.0055 17.1 0.2 3.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY48032.1 - 0.019 15.2 0.1 0.082 13.2 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY48032.1 - 0.032 14.2 1.9 0.51 10.4 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 ORY48032.1 - 0.17 12.3 0.5 1.3 9.6 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type AAA_23 PF13476.6 ORY48032.1 - 0.24 11.9 8.3 0.6 10.6 8.3 1.6 1 0 0 1 1 1 0 AAA domain CCDC50_N PF15295.6 ORY48033.1 - 0.26 11.5 5.8 1.1 9.4 1.2 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus CCDC50_N PF15295.6 ORY48036.1 - 0.47 10.6 3.0 0.33 11.1 0.3 1.8 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus HMMR_C PF15908.5 ORY48037.1 - 4.8e-06 26.9 13.3 4.8e-06 26.9 13.3 11.2 4 4 7 11 11 11 1 Hyaluronan mediated motility receptor C-terminal HMMR_N PF15905.5 ORY48037.1 - 5.7e-06 26.0 240.0 6.3e-05 22.6 24.5 9.9 1 1 7 9 9 9 4 Hyaluronan mediated motility receptor N-terminal Tropomyosin_1 PF12718.7 ORY48037.1 - 0.0055 16.9 2.5 0.0055 16.9 2.5 14.2 2 2 10 13 13 13 4 Tropomyosin like DUF4201 PF13870.6 ORY48037.1 - 0.024 14.4 0.3 0.024 14.4 0.3 16.1 2 2 12 15 15 15 0 Domain of unknown function (DUF4201) Bcr-Abl_Oligo PF09036.10 ORY48037.1 - 0.041 13.9 0.2 0.041 13.9 0.2 8.9 9 2 1 10 10 10 0 Bcr-Abl oncoprotein oligomerisation domain XTBD PF11952.8 ORY48037.1 - 0.17 11.7 4.0 1 9.2 1.1 3.8 2 0 0 2 2 2 0 XRN-Two Binding Domain, XTBD WD40_alt PF14077.6 ORY48037.1 - 1.2 9.0 10.8 36 4.3 0.1 6.3 6 0 0 6 6 6 0 Alternative WD40 repeat motif Filament PF00038.21 ORY48037.1 - 2.2 7.8 237.0 0.0096 15.5 8.3 9.9 1 1 6 9 9 9 0 Intermediate filament protein OPT PF03169.15 ORY48038.1 - 6.7e-102 342.1 46.4 7.9e-102 341.9 46.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF212 PF02681.14 ORY48038.1 - 0.022 14.9 0.6 4.5 7.4 0.0 3.3 3 0 0 3 3 3 0 Divergent PAP2 family DUF2644 PF10841.8 ORY48038.1 - 0.36 11.1 6.7 0.57 10.4 3.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2644) VWA PF00092.28 ORY48039.1 - 7.4e-21 75.2 0.0 1.3e-20 74.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 ORY48039.1 - 1.7e-13 51.1 0.0 4.2e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 ORY48039.1 - 4.3e-11 43.0 0.0 7.9e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 ORY48039.1 - 8.1e-06 25.4 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein zf-RING_2 PF13639.6 ORY48039.1 - 0.06 13.7 15.5 0.056 13.8 14.0 1.8 2 0 0 2 2 2 0 Ring finger domain zf-RING_4 PF14570.6 ORY48039.1 - 0.096 12.5 11.2 0.21 11.4 11.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain OPT PF03169.15 ORY48040.1 - 1.2e-105 354.5 49.7 1.4e-105 354.3 49.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2207 PF09972.9 ORY48040.1 - 5.2 5.7 9.2 0.088 11.6 0.6 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Esterase PF00756.20 ORY48041.1 - 1.1e-41 143.2 0.0 1.3e-41 142.9 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 ORY48041.1 - 1.3e-05 24.8 0.0 2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 ORY48041.1 - 2.3e-05 23.8 0.0 3.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 ORY48041.1 - 0.0005 19.6 0.3 0.007 15.9 0.3 2.1 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_1 PF00561.20 ORY48041.1 - 0.0078 15.9 0.1 0.009 15.7 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 ORY48041.1 - 0.012 14.5 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.25 ORY48041.1 - 0.019 14.8 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PAF-AH_p_II PF03403.13 ORY48041.1 - 0.069 11.6 0.0 0.12 10.9 0.0 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 ORY48041.1 - 0.091 13.4 3.1 0.087 13.4 0.6 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family Chlorophyllase PF07224.11 ORY48041.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Acetyltransf_3 PF13302.7 ORY48043.1 - 1e-13 52.2 0.0 1.5e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY48043.1 - 0.00017 21.8 0.0 0.00024 21.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family ZZ PF00569.17 ORY48044.1 - 0.011 15.5 7.2 0.024 14.5 7.2 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type CHGN PF05679.16 ORY48044.1 - 0.037 12.9 4.3 0.058 12.2 4.3 1.2 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase Forkhead_N PF08430.12 ORY48044.1 - 0.52 10.9 3.0 1.6 9.3 3.0 1.8 1 0 0 1 1 1 0 Forkhead N-terminal region TFIIA PF03153.13 ORY48044.1 - 0.86 9.5 16.9 1.7 8.5 16.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 ORY48044.1 - 4.2 6.2 28.1 6.7 5.6 28.1 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Rad52_Rad22 PF04098.15 ORY48045.1 - 6.7e-53 178.7 0.0 7.9e-53 178.5 0.0 1.0 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein DUF4407 PF14362.6 ORY48046.1 - 0.12 11.7 0.6 0.16 11.3 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Het-C PF07217.11 ORY48046.1 - 0.29 9.6 1.5 0.41 9.1 1.5 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Fez1 PF06818.15 ORY48048.1 - 4.8e-05 23.9 11.6 4.8e-05 23.9 11.6 3.4 1 1 2 3 3 3 2 Fez1 DUF2634 PF10934.8 ORY48048.1 - 0.41 10.8 3.4 0.82 9.8 0.4 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2634) CENP-F_leu_zip PF10473.9 ORY48048.1 - 3.5 7.7 39.5 0.09 12.8 5.4 4.9 2 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PKcGMP_CC PF16808.5 ORY48048.1 - 9.4 6.2 10.7 16 5.4 0.5 4.1 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase MMR_HSR1 PF01926.23 ORY48050.1 - 6.6e-16 58.4 0.1 1.8e-13 50.5 0.0 3.0 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY48050.1 - 3.7e-06 26.6 0.1 0.00017 21.1 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ORY48050.1 - 3.9e-05 23.6 0.1 0.0079 16.1 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 ORY48050.1 - 0.00021 21.4 0.4 0.0034 17.5 0.0 2.7 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 ORY48050.1 - 0.00057 19.5 0.1 0.96 9.0 0.0 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 ORY48050.1 - 0.0092 15.3 0.0 0.021 14.1 0.0 1.6 1 0 0 1 1 1 1 AIG1 family RapH_N PF18801.1 ORY48050.1 - 0.064 13.3 0.7 0.14 12.2 0.7 1.5 1 0 0 1 1 1 0 response regulator aspartate phosphatase H, N terminal SUZ PF12752.7 ORY48050.1 - 0.23 12.3 0.2 0.23 12.3 0.2 2.2 2 0 0 2 2 2 0 SUZ domain Roc PF08477.13 ORY48050.1 - 0.77 10.0 2.5 0.78 10.0 0.1 2.3 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Zn_clus PF00172.18 ORY48051.1 - 6.7e-08 32.5 7.7 8.5e-08 32.2 7.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tropomyosin_1 PF12718.7 ORY48052.1 - 4.9e-30 104.6 31.8 6.1e-30 104.3 31.8 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 ORY48052.1 - 1.7e-07 30.9 32.0 0.0013 18.2 13.8 2.2 1 1 1 2 2 2 2 Tropomyosin Spectrin PF00435.21 ORY48052.1 - 0.00058 20.3 19.7 0.0068 16.9 10.8 2.2 1 1 1 2 2 2 2 Spectrin repeat Ax_dynein_light PF10211.9 ORY48052.1 - 0.002 18.1 21.7 0.094 12.7 11.2 2.1 2 0 0 2 2 2 2 Axonemal dynein light chain DUF4094 PF13334.6 ORY48052.1 - 0.011 16.1 1.4 0.011 16.1 1.4 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4094) DUF641 PF04859.12 ORY48052.1 - 0.015 15.6 3.6 0.015 15.6 3.6 2.8 1 1 1 2 2 1 0 Plant protein of unknown function (DUF641) CLZ PF16526.5 ORY48052.1 - 0.019 15.3 22.8 0.13 12.6 3.8 3.2 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ATG16 PF08614.11 ORY48052.1 - 0.03 14.6 27.0 0.063 13.5 11.7 2.7 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 ORY48052.1 - 0.031 14.4 26.0 0.03 14.4 13.3 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HR1 PF02185.16 ORY48052.1 - 0.031 14.4 9.8 0.25 11.5 1.2 3.0 2 1 1 3 3 3 0 Hr1 repeat DUF4795 PF16043.5 ORY48052.1 - 0.035 13.7 20.5 0.072 12.7 20.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) GAS PF13851.6 ORY48052.1 - 0.037 13.4 28.4 0.21 10.9 28.4 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.20 ORY48052.1 - 0.039 13.9 4.2 0.039 13.9 4.2 3.7 1 1 3 4 4 4 0 Prefoldin subunit FlxA PF14282.6 ORY48052.1 - 0.039 13.9 10.2 0.11 12.4 7.3 2.5 1 1 1 2 2 2 0 FlxA-like protein Fez1 PF06818.15 ORY48052.1 - 0.056 13.9 22.8 0.091 13.2 22.2 1.5 1 1 0 1 1 1 0 Fez1 SlyX PF04102.12 ORY48052.1 - 0.064 13.9 15.5 2.8 8.6 3.6 3.2 1 1 2 3 3 3 0 SlyX TPR_MLP1_2 PF07926.12 ORY48052.1 - 0.075 13.1 27.1 0.39 10.8 22.6 3.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DHR10 PF18595.1 ORY48052.1 - 0.078 13.0 30.1 0.035 14.1 11.3 3.0 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DRTGG PF07085.12 ORY48052.1 - 0.092 12.5 0.2 0.16 11.8 0.2 1.3 1 0 0 1 1 1 0 DRTGG domain ADIP PF11559.8 ORY48052.1 - 0.1 12.7 21.3 0.71 9.9 6.7 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding DUF5320 PF17253.2 ORY48052.1 - 0.11 13.6 16.3 2.5 9.2 1.6 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5320) DivIC PF04977.15 ORY48052.1 - 0.24 11.2 21.9 0.042 13.6 4.9 3.2 1 1 2 3 3 3 0 Septum formation initiator LPP PF04728.13 ORY48052.1 - 0.25 11.7 12.9 7.6 7.0 2.5 4.0 3 1 1 4 4 4 0 Lipoprotein leucine-zipper ABC_tran_CTD PF16326.5 ORY48052.1 - 0.34 11.2 26.3 0.61 10.4 4.9 3.3 1 1 2 3 3 3 0 ABC transporter C-terminal domain Filament PF00038.21 ORY48052.1 - 0.35 10.4 24.8 0.6 9.6 11.0 2.1 1 1 1 2 2 2 0 Intermediate filament protein BRE1 PF08647.11 ORY48052.1 - 0.46 10.6 25.0 0.43 10.7 7.8 2.6 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Spc7 PF08317.11 ORY48052.1 - 0.51 9.2 27.5 0.17 10.7 13.2 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein Laminin_II PF06009.12 ORY48052.1 - 0.54 10.3 17.3 6.2 6.8 0.6 2.9 1 1 2 3 3 3 0 Laminin Domain II SHE3 PF17078.5 ORY48052.1 - 0.56 9.9 19.4 1.2 8.8 19.3 1.7 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF4407 PF14362.6 ORY48052.1 - 0.67 9.2 18.7 6.1 6.1 18.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.6 ORY48052.1 - 0.69 8.5 20.7 1.5 7.4 20.7 1.6 1 1 0 1 1 1 0 AAA domain DUF3450 PF11932.8 ORY48052.1 - 0.84 8.9 20.7 1.3 8.2 3.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) BLOC1_2 PF10046.9 ORY48052.1 - 0.88 9.9 19.6 1.1 9.6 2.3 2.9 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4200 PF13863.6 ORY48052.1 - 0.9 10.0 29.2 1.8 9.0 8.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF16 PF01519.16 ORY48052.1 - 1 9.9 18.3 0.29 11.6 3.8 3.0 1 1 2 3 3 3 0 Protein of unknown function DUF16 DUF87 PF01935.17 ORY48052.1 - 1 9.4 8.5 1.2 9.2 8.5 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain TMF_TATA_bd PF12325.8 ORY48052.1 - 1.1 9.5 24.0 2.9 8.1 13.8 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF1664 PF07889.12 ORY48052.1 - 1.2 9.2 13.4 1.4 9.0 2.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) CREPT PF16566.5 ORY48052.1 - 1.3 9.2 19.2 2.4 8.3 5.8 2.4 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour PspA_IM30 PF04012.12 ORY48052.1 - 1.4 8.5 28.1 1.4 8.5 9.9 2.7 1 1 2 3 3 3 0 PspA/IM30 family Lectin_N PF03954.14 ORY48052.1 - 1.5 8.6 11.8 7.4 6.3 0.5 3.0 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain ERM PF00769.19 ORY48052.1 - 1.5 8.6 29.5 9.2 6.0 29.2 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family TMF_DNA_bd PF12329.8 ORY48052.1 - 1.7 8.7 32.7 0.089 12.8 9.5 3.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.9 ORY48052.1 - 1.7 8.7 32.4 1.3 9.1 20.1 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cluap1 PF10234.9 ORY48052.1 - 1.8 7.9 21.8 0.071 12.5 6.6 2.4 1 1 1 2 2 2 0 Clusterin-associated protein-1 NPV_P10 PF05531.12 ORY48052.1 - 2 9.0 9.9 3.6 8.1 4.3 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 ORY48052.1 - 2.2 8.7 15.6 7 7.1 0.1 3.4 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF4472 PF14739.6 ORY48052.1 - 2.9 8.7 23.9 12 6.7 12.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF724 PF05266.14 ORY48052.1 - 3.1 7.6 24.6 3.2 7.5 12.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) GrpE PF01025.19 ORY48052.1 - 3.3 7.3 26.6 7.1 6.3 4.3 2.7 1 1 2 3 3 3 0 GrpE Rho_Binding PF08912.11 ORY48052.1 - 3.4 8.5 22.5 3.4 8.5 2.4 3.4 1 1 2 3 3 3 0 Rho Binding DUF2205 PF10224.9 ORY48052.1 - 5.8 7.0 16.8 0.97 9.5 7.4 3.1 2 1 1 3 3 3 0 Short coiled-coil protein Jnk-SapK_ap_N PF09744.9 ORY48052.1 - 5.8 7.1 27.0 1.4e+03 -0.6 27.0 2.2 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.10 ORY48052.1 - 6 7.1 14.6 7.2 6.8 4.0 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family BST2 PF16716.5 ORY48052.1 - 7.6 7.2 23.8 4 8.1 4.5 3.6 1 1 3 4 4 4 0 Bone marrow stromal antigen 2 LMBR1 PF04791.16 ORY48052.1 - 7.7 5.3 14.4 8.8 5.1 14.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CC2-LZ PF16516.5 ORY48052.1 - 8.2 6.9 23.1 0.97 9.8 6.4 3.1 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF2968 PF11180.8 ORY48052.1 - 8.8 5.9 16.4 10 5.7 7.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF4140 PF13600.6 ORY48052.1 - 9 6.8 21.3 6.3 7.3 2.4 3.0 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) HSP20 PF00011.21 ORY48053.1 - 3.6e-10 39.9 0.2 6.7e-10 39.0 0.2 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ORC6 PF05460.13 ORY48053.1 - 0.024 13.9 11.5 0.031 13.6 11.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Caskin-Pro-rich PF16907.5 ORY48054.1 - 7.7 7.1 11.2 5.7 7.5 1.6 2.7 2 0 0 2 2 2 0 Proline rich region of Caskin proteins AAA_33 PF13671.6 ORY48055.1 - 1.8e-15 57.3 0.0 2.5e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY48055.1 - 2.3e-05 25.0 0.0 3.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY48055.1 - 0.00021 21.6 0.1 0.0022 18.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 ORY48055.1 - 0.00029 20.2 0.0 0.00046 19.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_24 PF13479.6 ORY48055.1 - 0.00034 20.4 0.0 0.00049 19.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY48055.1 - 0.00055 20.3 0.0 0.00087 19.7 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain CPT PF07931.12 ORY48055.1 - 0.00068 19.5 0.1 0.0021 17.9 0.1 1.7 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_25 PF13481.6 ORY48055.1 - 0.0014 18.3 0.2 0.082 12.5 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 ORY48055.1 - 0.0025 18.1 0.1 0.0051 17.1 0.1 1.6 1 1 0 1 1 1 1 AAA domain GRP PF07172.11 ORY48055.1 - 0.0066 17.1 1.7 0.012 16.3 1.7 1.4 1 0 0 1 1 1 1 Glycine rich protein family ABC_tran PF00005.27 ORY48055.1 - 0.0077 16.7 0.2 0.12 12.8 0.1 2.1 1 1 0 2 2 2 1 ABC transporter KTI12 PF08433.10 ORY48055.1 - 0.013 15.0 0.0 0.023 14.2 0.0 1.4 1 1 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.20 ORY48055.1 - 0.018 15.0 0.1 0.048 13.6 0.1 1.7 1 1 0 1 1 1 0 Adenylylsulphate kinase RsgA_GTPase PF03193.16 ORY48055.1 - 0.02 14.8 0.1 0.038 13.9 0.0 1.4 1 1 0 1 1 1 0 RsgA GTPase Guanylate_kin PF00625.21 ORY48055.1 - 0.033 13.9 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase AAA_17 PF13207.6 ORY48055.1 - 0.054 13.9 0.0 0.081 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ORY48055.1 - 0.061 13.0 0.0 0.37 10.5 0.0 2.0 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 ORY48055.1 - 0.064 13.3 0.0 0.086 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Ploopntkinase1 PF18748.1 ORY48055.1 - 0.088 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 TsaE PF02367.17 ORY48055.1 - 0.15 12.1 0.0 0.23 11.5 0.0 1.4 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 ORY48055.1 - 0.16 11.1 0.0 0.34 10.0 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 ORY48055.1 - 0.2 11.5 0.0 0.31 11.0 0.0 1.2 1 0 0 1 1 1 0 NACHT domain Hpr_kinase_C PF07475.12 ORY48055.1 - 0.25 10.8 0.0 0.4 10.2 0.0 1.2 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain ABC_membrane PF00664.23 ORY48056.1 - 4.8e-19 69.1 3.3 4.8e-19 69.1 3.3 3.3 2 1 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY48056.1 - 0.064 13.8 0.0 0.96 10.0 0.0 2.6 2 1 1 3 3 3 0 ABC transporter AAA_21 PF13304.6 ORY48056.1 - 0.072 12.9 0.3 1 9.1 0.1 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 ORY48056.1 - 0.23 11.7 0.4 5.9 7.2 0.0 3.0 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 ORY48058.1 - 2.7e-50 170.4 0.1 8.9e-28 97.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORY48058.1 - 7.9e-16 58.5 10.7 3.2e-10 40.1 0.5 2.2 1 1 1 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ORY48058.1 - 3e-09 36.6 6.1 8.1e-05 22.2 0.4 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 ORY48058.1 - 2.8e-07 31.1 0.1 0.0083 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 ORY48058.1 - 2.8e-07 30.6 0.2 0.00089 19.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 ORY48058.1 - 9.5e-07 28.9 3.1 0.15 11.9 0.0 3.8 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY48058.1 - 1.2e-06 28.2 1.2 0.011 15.4 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY48058.1 - 2.2e-06 27.7 0.4 0.012 15.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 ORY48058.1 - 1.1e-05 25.1 0.9 0.016 14.7 0.2 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 ORY48058.1 - 1.6e-05 25.2 1.5 0.13 12.5 0.2 2.8 2 1 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 ORY48058.1 - 2e-05 24.6 1.2 0.44 10.4 0.0 3.4 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea T2SSE PF00437.20 ORY48058.1 - 7.2e-05 22.0 5.3 0.0073 15.4 0.0 3.0 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_30 PF13604.6 ORY48058.1 - 0.00035 20.3 0.4 0.058 13.1 0.1 2.5 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 ORY48058.1 - 0.00038 19.7 1.2 0.38 9.9 0.0 2.8 3 0 0 3 3 3 2 NB-ARC domain NACHT PF05729.12 ORY48058.1 - 0.00045 20.2 1.2 0.46 10.4 0.1 2.6 2 0 0 2 2 2 2 NACHT domain AAA_25 PF13481.6 ORY48058.1 - 0.00077 19.1 0.3 0.78 9.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 ORY48058.1 - 0.0011 18.6 5.0 0.11 12.0 0.4 2.7 3 0 0 3 3 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 ORY48058.1 - 0.0023 17.7 0.7 0.095 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 ORY48058.1 - 0.003 18.1 0.6 1.1 9.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 ORY48058.1 - 0.0046 16.9 3.6 0.59 10.0 0.2 2.9 3 0 0 3 3 3 1 NTPase FtsK_SpoIIIE PF01580.18 ORY48058.1 - 0.0047 16.3 0.8 0.041 13.2 0.1 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family RNA_helicase PF00910.22 ORY48058.1 - 0.0049 17.2 0.2 0.63 10.4 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 ORY48058.1 - 0.0054 17.2 1.5 13 6.2 0.0 3.6 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 ORY48058.1 - 0.0085 15.0 1.3 0.29 10.0 0.1 2.2 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 ORY48058.1 - 0.0092 15.7 0.4 0.1 12.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 ORY48058.1 - 0.0093 16.0 0.8 2.1 8.3 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Roc PF08477.13 ORY48058.1 - 0.0096 16.1 0.3 0.59 10.4 0.1 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DEAD PF00270.29 ORY48058.1 - 0.01 15.6 5.2 0.19 11.5 1.3 3.2 2 2 0 2 2 2 0 DEAD/DEAH box helicase AAA_19 PF13245.6 ORY48058.1 - 0.013 15.8 0.3 2.3 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 ORY48058.1 - 0.014 15.4 1.7 0.86 9.6 0.1 2.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.17 ORY48058.1 - 0.014 15.2 1.6 0.26 11.0 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 ORY48058.1 - 0.015 15.4 3.1 2.2 8.3 0.1 2.5 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.6 ORY48058.1 - 0.018 15.6 0.1 2.6 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 ORY48058.1 - 0.021 13.8 0.8 0.85 8.5 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 ORY48058.1 - 0.022 14.1 2.3 6 6.1 0.1 3.1 3 0 0 3 3 3 0 AIG1 family TsaE PF02367.17 ORY48058.1 - 0.024 14.6 0.3 5.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 ORY48058.1 - 0.025 14.7 2.1 1.6 8.9 0.1 2.9 2 1 1 3 3 2 0 AAA domain GTP_EFTU PF00009.27 ORY48058.1 - 0.026 14.1 0.1 6.4 6.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_11 PF13086.6 ORY48058.1 - 0.036 13.9 0.3 2.1 8.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain RNA12 PF10443.9 ORY48058.1 - 0.04 12.7 0.4 0.11 11.2 0.0 1.8 2 0 0 2 2 2 0 RNA12 protein Zeta_toxin PF06414.12 ORY48058.1 - 0.04 13.2 0.4 4.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.14 ORY48058.1 - 0.049 13.5 1.8 2.7 7.9 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.17 ORY48058.1 - 0.054 13.6 5.3 0.061 13.4 0.3 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain IstB_IS21 PF01695.17 ORY48058.1 - 0.059 13.1 1.0 4.2 7.0 0.0 3.2 3 1 1 4 4 3 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 ORY48058.1 - 0.091 12.5 0.1 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_13 PF13166.6 ORY48058.1 - 0.1 11.2 0.1 0.69 8.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Ploopntkinase3 PF18751.1 ORY48058.1 - 0.1 12.5 0.1 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_35 PF14516.6 ORY48058.1 - 0.11 11.3 1.5 1.8 7.3 0.0 3.0 4 0 0 4 4 3 0 AAA-like domain Septin PF00735.18 ORY48058.1 - 0.11 11.7 0.2 0.87 8.8 0.0 2.1 2 0 0 2 2 2 0 Septin Pox_A32 PF04665.12 ORY48058.1 - 0.15 11.5 3.9 21 4.5 0.1 3.5 4 0 0 4 4 3 0 Poxvirus A32 protein Mg_chelatase PF01078.21 ORY48058.1 - 0.15 11.4 0.0 5.8 6.2 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CoaE PF01121.20 ORY48058.1 - 0.5 10.0 1.8 1.3 8.6 0.1 2.4 2 1 0 2 2 2 0 Dephospho-CoA kinase AAA_14 PF13173.6 ORY48058.1 - 0.59 10.2 3.1 46 4.0 0.0 3.6 4 0 0 4 4 4 0 AAA domain DUF2075 PF09848.9 ORY48058.1 - 1.8 7.7 3.0 9.2 5.4 0.2 2.5 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) ATP-synt_I PF03899.15 ORY48059.1 - 0.0076 16.6 0.1 0.011 16.1 0.1 1.1 1 0 0 1 1 1 1 ATP synthase I chain DIE2_ALG10 PF04922.12 ORY48061.1 - 1.4e-120 403.2 14.7 1.6e-120 403.0 14.7 1.0 1 0 0 1 1 1 1 DIE2/ALG10 family PCI PF01399.27 ORY48062.1 - 5.1e-11 43.0 0.0 1e-10 42.1 0.0 1.5 1 0 0 1 1 1 1 PCI domain F-box_4 PF15966.5 ORY48063.1 - 0.017 15.0 0.6 0.059 13.3 0.0 2.1 3 0 0 3 3 3 0 F-box HNH_4 PF13395.6 ORY48064.1 - 5.7e-06 26.2 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 ORY48064.1 - 0.003 17.4 0.1 0.0078 16.0 0.0 1.8 2 0 0 2 2 2 1 HNH endonuclease HNH PF01844.23 ORY48064.1 - 0.0095 16.1 0.1 0.021 15.0 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease PINIT PF14324.6 ORY48064.1 - 0.043 14.1 0.3 1.5 9.2 0.0 2.1 2 0 0 2 2 2 0 PINIT domain tRNA-synt_2b PF00587.25 ORY48065.1 - 8.8e-44 149.6 0.0 1.6e-43 148.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 ORY48065.1 - 1.1e-11 44.7 3.2 1.4e-10 41.2 3.2 2.2 1 1 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 ORY48065.1 - 1.3e-10 41.2 0.0 2.8e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Basic PF01586.16 ORY48065.1 - 0.17 13.0 0.8 0.56 11.4 0.8 1.8 1 0 0 1 1 1 0 Myogenic Basic domain DUF5633 PF18656.1 ORY48065.1 - 1.1 9.2 4.3 0.34 10.9 0.1 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5633) Ank_2 PF12796.7 ORY48069.1 - 3.4e-33 114.1 0.0 6e-12 46.0 0.0 3.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY48069.1 - 1.1e-16 61.0 0.4 0.00011 22.6 0.1 4.5 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY48069.1 - 8e-16 56.5 0.7 0.16 12.6 0.0 6.9 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 ORY48069.1 - 1.5e-12 47.3 0.1 0.056 13.9 0.0 6.3 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 ORY48069.1 - 7.4e-11 42.1 0.7 0.54 10.7 0.0 6.5 2 2 5 7 7 7 3 Ankyrin repeats (many copies) DUF1910 PF08928.10 ORY48069.1 - 0.0018 18.3 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1910) F-box-like PF12937.7 ORY48070.1 - 1.1e-05 25.3 4.9 0.00013 21.8 1.4 2.5 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 ORY48070.1 - 2.2e-05 24.2 2.8 0.0004 20.2 0.2 2.9 3 0 0 3 3 3 1 F-box domain FAD_binding_3 PF01494.19 ORY48072.1 - 4.8e-24 85.3 1.9 4.3e-14 52.5 0.1 2.7 2 2 1 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 ORY48072.1 - 2.8e-07 30.1 4.2 0.00021 20.7 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY48072.1 - 3.1e-05 23.0 0.5 0.14 11.0 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase DAO PF01266.24 ORY48072.1 - 8.4e-05 22.3 0.7 0.0039 16.8 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY48072.1 - 9.8e-05 22.5 0.1 0.00031 20.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 ORY48072.1 - 0.00012 21.5 2.1 0.056 12.7 0.1 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY48072.1 - 0.00046 19.0 0.2 0.0019 17.0 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 ORY48072.1 - 0.0012 19.3 0.8 1.7 9.3 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY48072.1 - 0.009 15.1 0.8 0.018 14.1 0.8 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 ORY48072.1 - 0.028 14.4 1.2 2 8.4 0.1 3.6 4 0 0 4 4 4 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 ORY48072.1 - 0.048 12.7 0.4 0.1 11.7 0.4 1.5 1 0 0 1 1 1 0 FAD binding domain SE PF08491.10 ORY48072.1 - 0.06 12.4 0.1 0.31 10.0 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase SAM_1 PF00536.30 ORY48074.1 - 2e-11 44.2 0.0 3.3e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 ORY48074.1 - 3.1e-11 43.2 0.0 5.2e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Arrestin_N PF00339.29 ORY48074.1 - 1.5e-08 34.8 0.1 4.8e-07 29.9 0.0 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY48074.1 - 0.0001 22.8 0.0 0.0042 17.5 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain SAM_PNT PF02198.16 ORY48074.1 - 0.0047 16.9 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_Ste50p PF09235.10 ORY48074.1 - 0.0088 16.3 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Ste50p, sterile alpha motif Rgp1 PF08737.10 ORY48074.1 - 0.05 12.8 0.4 0.12 11.6 0.3 1.6 1 1 0 1 1 1 0 Rgp1 DUF4597 PF15366.6 ORY48074.1 - 0.54 10.0 5.9 0.24 11.1 3.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4597) Clr5 PF14420.6 ORY48076.1 - 0.055 13.7 0.5 0.23 11.7 0.2 1.9 2 0 0 2 2 2 0 Clr5 domain zf-AN1 PF01428.16 ORY48080.1 - 7.7e-15 54.8 32.2 3.5e-08 33.5 8.4 4.0 3 1 1 4 4 4 2 AN1-like Zinc finger zf-Di19 PF05605.12 ORY48080.1 - 0.0084 16.4 9.1 0.67 10.3 0.2 2.8 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding DUF753 PF05444.12 ORY48080.1 - 1.5 8.8 25.4 12 5.8 9.7 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF753) Sgf11 PF08209.11 ORY48080.1 - 4.7 6.9 12.7 2 8.1 0.1 3.6 4 0 0 4 4 4 0 Sgf11 (transcriptional regulation protein) Transp_Tc5_C PF04236.15 ORY48080.1 - 7 7.1 22.4 4.4 7.7 6.2 3.1 2 1 1 3 3 3 0 Tc5 transposase C-terminal domain bZIP_1 PF00170.21 ORY48081.1 - 3.8e-06 26.9 8.4 3.8e-06 26.9 8.4 2.3 3 0 0 3 3 3 1 bZIP transcription factor Cnn_1N PF07989.11 ORY48081.1 - 0.023 14.8 1.8 0.023 14.8 1.8 2.4 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF3016 PF11454.8 ORY48081.1 - 0.044 13.5 0.1 0.088 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) PRKG1_interact PF15898.5 ORY48081.1 - 0.076 13.9 5.1 0.9 10.5 1.2 2.7 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Spc24 PF08286.11 ORY48081.1 - 0.15 12.3 0.2 0.15 12.3 0.2 2.7 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 ZapB PF06005.12 ORY48081.1 - 2.3 8.7 9.3 0.29 11.6 2.5 2.7 2 2 0 2 2 2 0 Cell division protein ZapB YabA PF06156.13 ORY48081.1 - 4.9 7.9 7.2 7.7 7.2 2.3 2.7 1 1 0 2 2 2 0 Initiation control protein YabA LRR_4 PF12799.7 ORY48082.1 - 6.3e-07 29.6 17.6 0.0002 21.7 0.2 6.4 5 2 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY48082.1 - 0.0053 16.5 1.1 0.0053 16.5 1.1 3.9 5 0 0 5 5 5 1 Leucine rich repeat DUF5460 PF17544.2 ORY48082.1 - 0.0082 15.2 0.6 0.011 14.7 0.6 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5460) HTH_37 PF13744.6 ORY48082.1 - 0.023 14.7 2.3 0.67 10.0 0.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain LRR_9 PF14580.6 ORY48082.1 - 0.11 12.0 3.5 0.08 12.4 1.0 2.1 3 0 0 3 3 3 0 Leucine-rich repeat LRR_6 PF13516.6 ORY48082.1 - 3.7 7.8 11.8 15 5.9 0.0 6.2 7 0 0 7 7 7 0 Leucine Rich repeat LRR_1 PF00560.33 ORY48082.1 - 8.5 7.4 10.2 5.3e+02 1.9 0.0 6.3 5 1 0 5 5 5 0 Leucine Rich Repeat F-box-like PF12937.7 ORY48083.1 - 1.5e-09 37.6 0.3 3.2e-09 36.5 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY48083.1 - 0.0015 18.4 0.1 0.0044 16.9 0.1 1.8 1 0 0 1 1 1 1 F-box domain ClpS PF02617.17 ORY48084.1 - 1.3e-10 40.9 0.1 3e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS I_LWEQ PF01608.17 ORY48085.1 - 1.6e-43 148.6 8.8 1.6e-43 148.6 8.8 6.3 5 1 2 7 7 7 1 I/LWEQ domain ANTH PF07651.16 ORY48085.1 - 7.1e-11 41.6 7.4 9.2e-06 24.8 0.0 4.4 3 2 0 3 3 3 2 ANTH domain DUF604 PF04646.12 ORY48085.1 - 6.4e-10 38.9 0.0 1.6e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 ORY48085.1 - 2.2e-09 37.1 0.0 5.9e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Fringe-like PAN_4 PF14295.6 ORY48085.1 - 3e-07 30.2 2.5 8.2e-07 28.8 2.5 1.8 1 0 0 1 1 1 1 PAN domain Galactosyl_T PF01762.21 ORY48085.1 - 6.6e-06 26.1 0.2 0.0002 21.2 0.2 2.5 1 1 0 1 1 1 1 Galactosyltransferase Methyltr_RsmB-F PF01189.17 ORY48086.1 - 1.5e-17 63.9 0.1 1.5e-17 63.9 0.1 1.7 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 ORY48086.1 - 0.00042 20.1 0.1 0.00087 19.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORY48086.1 - 0.00081 19.2 0.0 0.0025 17.6 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 ORY48086.1 - 0.047 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FAM60A PF15396.6 ORY48086.1 - 0.15 12.1 1.7 0.68 9.9 0.1 2.4 2 0 0 2 2 2 0 Protein Family FAM60A SpoIIIAH PF12685.7 ORY48086.1 - 0.47 10.2 6.8 0.048 13.5 1.4 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein MARVEL PF01284.23 ORY48087.1 - 5e-05 23.4 9.6 7.1e-05 22.9 9.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain zf-4CXXC_R1 PF10497.9 ORY48088.1 - 1.3e-22 79.8 1.2 1.8e-22 79.4 1.2 1.1 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Pheromone PF08015.11 ORY48089.1 - 0.62 11.1 2.5 9.4 7.4 0.1 2.3 1 1 1 2 2 2 0 Fungal mating-type pheromone RTA1 PF04479.13 ORY48092.1 - 3.6e-22 79.0 9.0 2e-19 70.0 9.0 2.3 1 1 0 1 1 1 1 RTA1 like protein TAP_C PF03943.13 ORY48092.1 - 0.12 12.0 0.2 1.6 8.4 0.1 2.3 2 0 0 2 2 2 0 TAP C-terminal domain F-box-like PF12937.7 ORY48094.1 - 3.5e-05 23.6 0.0 8.7e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 ORY48094.1 - 0.045 13.6 0.8 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 F-box PIG-L PF02585.17 ORY48095.1 - 4.7e-24 85.5 0.1 9.1e-24 84.6 0.0 1.5 2 0 0 2 2 2 1 GlcNAc-PI de-N-acetylase DUF3747 PF12565.8 ORY48095.1 - 0.049 13.0 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3747) Chalcone_2 PF16035.5 ORY48096.1 - 1.1e-31 110.2 0.1 2.8e-31 108.9 0.1 1.6 1 1 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 ORY48096.1 - 7.1e-06 26.2 0.1 0.076 13.1 0.0 2.2 2 0 0 2 2 2 2 Chalcone isomerase-like Chalcone PF02431.15 ORY48096.1 - 0.0015 18.0 0.0 0.0023 17.4 0.0 1.3 1 1 0 1 1 1 1 Chalcone-flavanone isomerase UPF0564 PF10595.9 ORY48097.1 - 2.4e-24 86.1 42.9 2.4e-24 86.1 42.9 2.8 2 1 0 2 2 2 1 Uncharacterised protein family UPF0564 HXXSHH PF07586.11 ORY48097.1 - 0.0056 16.3 1.8 0.02 14.5 1.8 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1552) Lebercilin PF15619.6 ORY48098.1 - 0.13 11.9 12.4 0.031 13.9 7.9 2.0 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 ORY48098.1 - 0.89 8.9 16.4 0.23 10.8 11.4 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF484 PF04340.12 ORY48099.1 - 0.07 12.8 4.3 0.056 13.1 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF484 RET_CLD3 PF17812.1 ORY48099.1 - 0.13 12.5 0.3 0.51 10.6 0.0 2.1 2 0 0 2 2 2 0 RET Cadherin like domain 3 Fez1 PF06818.15 ORY48099.1 - 1.1 9.7 17.1 0.56 10.6 13.7 2.2 1 1 1 2 2 2 0 Fez1 DUF5446 PF17522.2 ORY48099.1 - 1.5 9.1 8.8 0.22 11.7 2.2 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5446) KELK PF15796.5 ORY48099.1 - 1.5 9.3 13.4 0.17 12.3 6.8 2.6 2 1 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase bZIP_1 PF00170.21 ORY48100.1 - 4.1e-07 30.0 5.9 4.1e-07 30.0 5.9 2.8 3 0 0 3 3 3 1 bZIP transcription factor ATG16 PF08614.11 ORY48100.1 - 0.003 17.8 6.9 0.12 12.6 4.6 2.3 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) TSC22 PF01166.18 ORY48100.1 - 0.025 14.9 6.7 4.9 7.5 0.9 3.5 2 1 1 3 3 3 0 TSC-22/dip/bun family DUF2452 PF10504.9 ORY48100.1 - 0.034 13.6 1.8 0.035 13.6 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2452) MCR_C PF04609.12 ORY48100.1 - 0.045 12.8 0.4 0.65 9.0 0.5 2.0 1 1 0 2 2 2 0 Methyl-coenzyme M reductase operon protein C NPV_P10 PF05531.12 ORY48100.1 - 0.074 13.5 1.0 1.3 9.5 0.5 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Nup54_57_C PF18570.1 ORY48100.1 - 0.27 10.9 0.1 0.27 10.9 0.1 2.5 2 0 0 2 2 2 0 NUP57/Nup54 C-terminal domain BLOC1_2 PF10046.9 ORY48100.1 - 0.35 11.2 4.3 0.4 11.0 1.9 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TcpS PF17456.2 ORY48100.1 - 0.41 10.7 3.3 1.2 9.1 1.5 2.1 1 1 1 2 2 2 0 Toxin-coregulated pilus protein S Pox_A_type_inc PF04508.12 ORY48100.1 - 0.79 9.7 7.7 11 6.0 0.3 3.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat FlxA PF14282.6 ORY48100.1 - 1.3 9.1 7.6 14 5.8 0.2 2.4 2 0 0 2 2 2 0 FlxA-like protein zf-C4pol PF14260.6 ORY48100.1 - 1.7 9.2 5.8 3.3 8.2 0.9 2.5 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta bZIP_2 PF07716.15 ORY48100.1 - 7.7 6.7 15.8 2.5 8.2 7.8 3.0 2 1 1 3 3 3 0 Basic region leucine zipper DUF3730 PF12530.8 ORY48101.1 - 9.5e-11 41.7 6.7 1.9e-10 40.7 0.0 3.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3730) HEAT_2 PF13646.6 ORY48101.1 - 0.0006 20.2 0.3 7.8 7.0 0.0 6.1 5 1 0 5 5 5 1 HEAT repeats Arrestin_N PF00339.29 ORY48102.1 - 1.5e-08 34.8 0.0 4e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY48102.1 - 3.2e-07 30.9 0.0 0.0019 18.6 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Vma12 PF11712.8 ORY48103.1 - 2e-17 63.6 0.0 4.4e-17 62.4 0.0 1.5 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase GtrA PF04138.14 ORY48103.1 - 4.6e-05 23.6 1.5 7.4e-05 23.0 1.5 1.3 1 0 0 1 1 1 1 GtrA-like protein DUF4229 PF14012.6 ORY48103.1 - 0.21 11.7 3.9 0.46 10.6 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF1295 PF06966.12 ORY48105.1 - 7.3e-50 169.7 3.5 8.4e-50 169.5 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 ORY48105.1 - 8.8e-06 25.8 2.7 8.8e-06 25.8 2.7 1.8 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 ORY48105.1 - 0.0015 18.9 0.2 0.0053 17.2 0.1 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family O_anti_polymase PF01901.16 ORY48105.1 - 0.014 14.6 1.1 0.059 12.6 1.1 1.9 1 1 0 1 1 1 0 Putative O-antigen polymerase PEMT PF04191.13 ORY48105.1 - 0.052 14.0 2.5 0.089 13.2 1.5 2.0 1 1 0 1 1 1 0 Phospholipid methyltransferase SAM_2 PF07647.17 ORY48106.1 - 2e-11 43.8 0.0 3.4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Arrestin_N PF00339.29 ORY48106.1 - 2.4e-08 34.1 0.0 1.6e-07 31.5 0.0 2.2 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain SAM_1 PF00536.30 ORY48106.1 - 6.8e-08 32.8 0.0 1.3e-07 32.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Arrestin_C PF02752.22 ORY48106.1 - 0.00078 19.9 0.0 0.11 12.9 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain SAM_PNT PF02198.16 ORY48106.1 - 0.0025 17.7 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain CD36 PF01130.21 ORY48106.1 - 0.048 12.2 0.1 0.1 11.1 0.1 1.5 1 0 0 1 1 1 0 CD36 family SAM_2 PF07647.17 ORY48107.1 - 4.7e-13 49.0 0.0 9.4e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Arrestin_N PF00339.29 ORY48107.1 - 4.4e-11 43.0 0.0 7.9e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain SAM_1 PF00536.30 ORY48107.1 - 1.9e-08 34.6 0.0 3.5e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Arrestin_C PF02752.22 ORY48107.1 - 6.6e-06 26.6 0.2 3.3e-05 24.3 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Rgp1 PF08737.10 ORY48107.1 - 0.00075 18.8 0.1 0.002 17.4 0.1 1.6 2 0 0 2 2 2 1 Rgp1 SAM_Ste50p PF09235.10 ORY48107.1 - 0.014 15.6 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Arrestin_N PF00339.29 ORY48108.1 - 2.7e-16 60.0 0.0 9.9e-16 58.1 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain SAM_2 PF07647.17 ORY48108.1 - 5.9e-11 42.3 0.0 1.1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Arrestin_C PF02752.22 ORY48108.1 - 2e-10 41.2 0.2 8.6e-07 29.5 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain SAM_1 PF00536.30 ORY48108.1 - 1.8e-09 37.9 0.0 3.2e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Rgp1 PF08737.10 ORY48108.1 - 0.0035 16.6 0.3 0.026 13.7 0.1 2.2 2 0 0 2 2 2 1 Rgp1 SAM_3 PF18016.1 ORY48108.1 - 0.049 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 ORY48108.1 - 0.079 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain SAM_1 PF00536.30 ORY48109.1 - 3.6e-11 43.4 0.0 6.3e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 ORY48109.1 - 1.1e-10 41.4 0.0 2.4e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Arrestin_N PF00339.29 ORY48109.1 - 1.8e-08 34.6 0.0 1.5e-07 31.5 0.0 2.5 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY48109.1 - 7e-07 29.8 0.0 0.00061 20.2 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain SAM_Ste50p PF09235.10 ORY48109.1 - 0.0027 17.9 0.1 0.0049 17.1 0.1 1.4 1 0 0 1 1 1 1 Ste50p, sterile alpha motif SAM_2 PF07647.17 ORY48110.1 - 6.5e-10 39.0 0.1 1.1e-09 38.3 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORY48110.1 - 2.5e-08 34.2 0.1 4.6e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Arrestin_N PF00339.29 ORY48110.1 - 8.1e-06 26.0 0.0 2.4e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 ORY48110.1 - 0.034 13.3 0.0 0.054 12.7 0.0 1.4 1 0 0 1 1 1 0 Rgp1 Arrestin_C PF02752.22 ORY48110.1 - 0.045 14.2 0.0 0.86 10.1 0.0 2.3 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain SAM_PNT PF02198.16 ORY48110.1 - 0.19 11.7 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Arrestin_N PF00339.29 ORY48111.1 - 2.3e-08 34.2 3.7 3.9e-08 33.5 0.0 2.8 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain SAM_1 PF00536.30 ORY48111.1 - 3.6e-08 33.7 0.0 6.8e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Arrestin_C PF02752.22 ORY48111.1 - 3.7e-07 30.7 1.0 0.00029 21.3 0.2 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain ZU5 PF00791.20 ORY48111.1 - 0.026 14.9 1.9 0.66 10.4 0.0 3.4 3 1 0 3 3 3 0 ZU5 domain SAM_Ste50p PF09235.10 ORY48111.1 - 0.085 13.1 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Exonuc_VII_L PF02601.15 ORY48111.1 - 1.3 8.5 9.8 2.2 7.8 9.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Rgp1 PF08737.10 ORY48111.1 - 1.7 7.8 11.3 0.38 9.9 0.1 2.6 3 0 0 3 3 3 0 Rgp1 IHABP4_N PF16174.5 ORY48111.1 - 2 9.0 10.5 4.1 8.0 10.5 1.4 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal SAM_1 PF00536.30 ORY48112.1 - 4.7e-05 23.7 0.1 9.8e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 ORY48112.1 - 0.00025 21.1 0.2 0.00046 20.2 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Arrestin_C PF02752.22 ORY48112.1 - 0.0003 21.2 0.5 0.00058 20.3 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY48112.1 - 0.0062 16.6 0.2 0.02 15.0 0.2 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain DUF2076 PF09849.9 ORY48112.1 - 0.028 14.5 0.2 0.044 13.8 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Rgp1 PF08737.10 ORY48112.1 - 0.052 12.7 0.6 2.7 7.0 0.0 2.8 2 1 0 2 2 2 0 Rgp1 SAM_1 PF00536.30 ORY48113.1 - 2.1e-11 44.1 0.0 3.9e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 ORY48113.1 - 4.5e-09 36.3 0.0 7.7e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Arrestin_N PF00339.29 ORY48113.1 - 0.0014 18.7 0.0 0.0056 16.8 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain KDZ PF18758.1 ORY48115.1 - 9.3e-17 61.4 0.1 1.2e-16 61.0 0.1 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Peptidase_M23 PF01551.22 ORY48117.1 - 3.3e-09 36.9 0.2 7.7e-09 35.7 0.2 1.7 1 0 0 1 1 1 1 Peptidase family M23 RnfC_N PF13375.6 ORY48117.1 - 0.11 12.4 0.1 9.1 6.3 0.0 2.4 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain U3_assoc_6 PF08640.11 ORY48118.1 - 2.1e-29 101.4 5.0 2.1e-29 101.4 5.0 2.0 2 1 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 ORY48118.1 - 0.0043 17.8 0.0 0.99 10.4 0.1 4.0 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY48118.1 - 0.014 15.7 0.3 22 5.7 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat NRDE-2 PF08424.10 ORY48118.1 - 0.05 12.7 0.4 0.76 8.8 0.2 2.3 2 1 0 2 2 2 0 NRDE-2, necessary for RNA interference TPR_19 PF14559.6 ORY48118.1 - 0.14 12.7 0.1 37 4.9 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat CH_2 PF06294.11 ORY48120.1 - 5e-29 100.3 0.0 9.3e-29 99.4 0.0 1.5 1 0 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 ORY48120.1 - 7.8e-15 54.5 0.0 1.4e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.31 ORY48120.1 - 0.0018 18.4 0.0 0.003 17.7 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain HOOK PF05622.12 ORY48120.1 - 0.0031 15.8 0.1 0.044 11.9 0.0 2.0 2 0 0 2 2 2 1 HOOK protein Methyltransf_11 PF08241.12 ORY48121.1 - 1.4e-16 60.9 0.0 2.4e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY48121.1 - 1.9e-14 54.1 0.0 3.4e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY48121.1 - 3.8e-07 30.8 0.0 6.3e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY48121.1 - 1.9e-06 27.8 0.0 2.6e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY48121.1 - 7.8e-06 25.4 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.12 ORY48121.1 - 0.0005 19.9 0.0 0.00084 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_31 PF13847.6 ORY48121.1 - 0.001 18.9 0.0 0.0018 18.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 ORY48121.1 - 0.018 14.1 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_PK PF05891.12 ORY48121.1 - 0.018 14.5 0.0 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase Methyltransf_16 PF10294.9 ORY48121.1 - 0.037 13.7 0.0 0.096 12.4 0.0 1.6 2 0 0 2 2 2 0 Lysine methyltransferase DUF5319 PF17252.2 ORY48121.1 - 0.045 14.0 0.0 0.22 11.8 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5319) Methyltransf_8 PF05148.15 ORY48121.1 - 0.059 13.2 0.0 0.098 12.5 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Ribosomal_S28e PF01200.18 ORY48122.1 - 3.5e-32 110.2 0.9 4.9e-32 109.7 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S28e SAM_decarbox PF01536.16 ORY48123.1 - 1.5e-112 376.2 0.0 7.1e-106 354.2 0.0 2.3 2 1 0 2 2 2 2 Adenosylmethionine decarboxylase KH_6 PF15985.5 ORY48124.1 - 4.2e-18 65.4 0.2 1.2e-17 64.0 0.0 1.9 2 0 0 2 2 2 1 KH domain Rrp40_N PF18311.1 ORY48124.1 - 4.6e-08 32.9 0.0 1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain DUF2373 PF10180.9 ORY48125.1 - 0.056 13.3 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) WD40 PF00400.32 ORY48126.1 - 1.7e-18 66.6 27.1 9e-05 23.2 2.1 7.5 8 0 0 8 8 8 4 WD domain, G-beta repeat Nup160 PF11715.8 ORY48126.1 - 0.0076 14.9 0.6 3.2 6.3 0.1 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY48126.1 - 0.02 14.2 0.2 0.76 9.0 0.3 2.4 2 1 0 2 2 2 0 WD40-like domain DUF5544 PF17698.1 ORY48126.1 - 0.1 12.7 0.1 2.3 8.3 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5544) zf-C3HC4_3 PF13920.6 ORY48128.1 - 4.2e-07 29.7 6.5 7.7e-07 28.9 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY48128.1 - 0.0011 18.8 8.0 0.0026 17.6 8.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY48128.1 - 0.0091 15.8 9.0 0.025 14.4 9.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 ORY48128.1 - 0.014 15.5 3.5 0.033 14.3 3.5 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_5 PF14634.6 ORY48128.1 - 0.028 14.4 8.6 0.028 14.4 8.6 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_2 PF13639.6 ORY48128.1 - 0.041 14.2 9.7 0.096 13.0 9.7 1.7 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 ORY48128.1 - 0.14 12.1 6.5 0.36 10.7 6.5 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF971 PF06155.12 ORY48128.1 - 0.16 12.7 0.0 0.16 12.7 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF971) zf-RING_4 PF14570.6 ORY48128.1 - 0.41 10.5 5.4 1.5 8.7 5.4 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1664 PF07889.12 ORY48129.1 - 0.0097 15.9 2.0 2 8.5 0.4 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1664) DUF16 PF01519.16 ORY48129.1 - 2.1 8.8 6.3 3.5 8.2 3.8 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.12 ORY48129.1 - 2.7 8.7 5.7 16 6.2 3.0 2.9 2 1 0 2 2 2 0 SlyX DUF4140 PF13600.6 ORY48129.1 - 8.8 6.8 8.5 0.84 10.1 1.1 2.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) FAD_binding_3 PF01494.19 ORY48131.1 - 2.1e-09 37.1 0.1 3.9e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Myosin_N PF02736.19 ORY48131.1 - 0.14 12.0 0.3 0.27 11.1 0.3 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain ABC_membrane PF00664.23 ORY48132.1 - 9.7e-56 189.4 19.4 2e-27 96.5 5.8 3.9 2 2 1 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY48132.1 - 1.4e-33 116.3 0.0 2.8e-16 60.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY48132.1 - 2.7e-05 23.7 0.9 1.9 7.8 0.1 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY48132.1 - 0.0001 22.4 0.8 0.27 11.3 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 ORY48132.1 - 0.00046 20.7 0.4 0.093 13.2 0.1 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ORY48132.1 - 0.0008 19.4 0.0 0.17 11.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 ORY48132.1 - 0.00084 19.0 0.4 0.19 11.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 ORY48132.1 - 0.0013 18.5 3.7 0.57 10.0 0.0 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY48132.1 - 0.0068 16.8 0.0 1.9 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY48132.1 - 0.008 16.5 1.1 0.77 10.0 0.0 2.7 3 0 0 3 3 2 1 AAA domain T2SSE PF00437.20 ORY48132.1 - 0.018 14.1 0.3 1.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.23 ORY48132.1 - 0.019 15.0 0.1 0.72 9.9 0.0 2.4 2 0 0 2 2 2 0 Dynamin family AAA_21 PF13304.6 ORY48132.1 - 0.021 14.7 0.6 0.77 9.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system MeaB PF03308.16 ORY48132.1 - 0.034 13.1 0.3 0.071 12.1 0.3 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 ORY48132.1 - 0.05 13.8 0.5 1.6 9.0 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CbiA PF01656.23 ORY48132.1 - 0.088 12.9 1.6 26 4.9 0.1 3.4 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF87 PF01935.17 ORY48132.1 - 0.14 12.2 4.1 0.47 10.5 0.1 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain TrwB_AAD_bind PF10412.9 ORY48132.1 - 0.15 10.9 3.9 5.1 5.9 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Cyt_c_ox_IV PF12270.8 ORY48132.1 - 0.76 9.9 5.4 1.8 8.7 0.7 3.4 3 0 0 3 3 2 0 Cytochrome c oxidase subunit IV cobW PF02492.19 ORY48132.1 - 1.2 8.7 4.3 1.8 8.1 0.8 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 ORY48132.1 - 6.7 6.4 5.9 25 4.5 0.1 2.8 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 ORY48136.1 - 1.9e-49 167.7 2.9 3.1e-26 92.5 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 ORY48136.1 - 1.2e-34 120.2 33.6 8.8e-28 97.7 12.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ORY48136.1 - 1.1e-12 47.9 0.0 4.2e-05 23.1 0.3 5.0 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 ORY48136.1 - 1.6e-12 47.9 0.4 0.046 13.5 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 ORY48136.1 - 1.1e-07 31.9 0.1 0.025 14.6 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY48136.1 - 8.1e-07 29.1 0.1 0.022 14.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 ORY48136.1 - 1.5e-06 27.8 0.8 0.059 13.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_7 PF12775.7 ORY48136.1 - 1.8e-06 27.6 0.3 0.025 14.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_16 PF13191.6 ORY48136.1 - 2.3e-06 28.1 0.1 0.042 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 ORY48136.1 - 2.9e-05 24.4 2.0 0.44 10.8 0.1 3.3 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 ORY48136.1 - 7.1e-05 22.0 0.2 0.011 14.8 0.0 2.8 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_25 PF13481.6 ORY48136.1 - 0.00062 19.4 0.0 1 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 ORY48136.1 - 0.00065 19.8 1.3 0.3 11.1 0.1 2.5 2 0 0 2 2 2 1 Dynamin family ATP-synt_ab PF00006.25 ORY48136.1 - 0.00097 18.8 0.1 0.66 9.6 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.6 ORY48136.1 - 0.00098 19.7 2.0 0.75 10.3 0.1 2.6 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 ORY48136.1 - 0.001 18.8 0.0 0.13 12.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 ORY48136.1 - 0.0012 18.9 0.5 0.014 15.5 0.1 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain NACHT PF05729.12 ORY48136.1 - 0.0016 18.4 0.3 1.8 8.4 0.0 2.8 2 0 0 2 2 2 1 NACHT domain ATPase_2 PF01637.18 ORY48136.1 - 0.0018 18.2 0.9 2.3 8.1 0.0 3.3 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 ORY48136.1 - 0.0026 18.1 0.0 3 8.3 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_13 PF13166.6 ORY48136.1 - 0.0048 15.6 1.8 0.01 14.5 1.3 1.6 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 ORY48136.1 - 0.0051 16.6 0.2 3.2 7.4 0.0 3.0 3 0 0 3 3 3 1 IstB-like ATP binding protein NB-ARC PF00931.22 ORY48136.1 - 0.0053 16.0 0.6 1.8 7.6 0.1 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_15 PF13175.6 ORY48136.1 - 0.0054 16.5 3.9 0.87 9.2 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain AAA_18 PF13238.6 ORY48136.1 - 0.0085 16.6 0.2 1.3 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 ORY48136.1 - 0.0097 15.5 0.5 6.2 6.4 0.0 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.9 ORY48136.1 - 0.024 13.6 0.4 0.24 10.3 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 ORY48136.1 - 0.025 15.0 4.4 2 8.9 0.1 3.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ORY48136.1 - 0.026 14.2 0.1 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain CoaE PF01121.20 ORY48136.1 - 0.036 13.8 0.2 0.31 10.7 0.0 2.4 2 0 0 2 2 2 0 Dephospho-CoA kinase NTPase_1 PF03266.15 ORY48136.1 - 0.043 13.7 1.4 1.9 8.4 0.1 3.0 3 0 0 3 3 2 0 NTPase MeaB PF03308.16 ORY48136.1 - 0.048 12.6 0.2 0.78 8.7 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 ORY48136.1 - 0.052 13.8 0.2 11 6.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 ORY48136.1 - 0.054 13.5 0.1 14 5.7 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Roc PF08477.13 ORY48136.1 - 0.057 13.6 0.2 5.8 7.2 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_5 PF07728.14 ORY48136.1 - 0.07 13.1 0.3 14 5.6 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 ORY48136.1 - 0.086 12.2 0.3 0.31 10.3 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 ORY48136.1 - 0.091 12.0 0.2 5.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin GTP_EFTU PF00009.27 ORY48136.1 - 0.093 12.3 0.5 25 4.3 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain SbcCD_C PF13558.6 ORY48136.1 - 0.13 12.5 0.0 10 6.4 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 ORY48136.1 - 0.17 11.8 0.6 6.8 6.6 0.0 3.3 3 0 0 3 3 3 0 Rad17 P-loop domain ResIII PF04851.15 ORY48136.1 - 0.18 11.8 0.5 6.9 6.6 0.0 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit dNK PF01712.19 ORY48136.1 - 0.63 9.9 2.4 7.1 6.4 0.2 2.5 2 0 0 2 2 2 0 Deoxynucleoside kinase ATP_bind_1 PF03029.17 ORY48136.1 - 2.8 7.6 7.4 1.1 8.9 0.1 3.4 5 0 0 5 5 3 0 Conserved hypothetical ATP binding protein Aminotran_1_2 PF00155.21 ORY48137.1 - 3.8e-22 79.0 0.0 5e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 ORY48137.1 - 9.4e-13 47.7 0.0 1.3e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Fra10Ac1 PF09725.9 ORY48138.1 - 3.4e-51 172.5 0.2 8.3e-51 171.3 0.2 1.7 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 FAM76 PF16046.5 ORY48138.1 - 0.034 13.5 12.7 0.011 15.1 9.3 1.7 2 0 0 2 2 2 0 FAM76 protein FAM60A PF15396.6 ORY48138.1 - 0.081 12.9 8.3 0.17 11.9 8.3 1.5 1 0 0 1 1 1 0 Protein Family FAM60A DCA16 PF15349.6 ORY48138.1 - 0.22 11.0 2.4 0.35 10.4 1.4 1.7 2 0 0 2 2 2 0 DDB1- and CUL4-associated factor 16 FYDLN_acid PF09538.10 ORY48138.1 - 0.6 10.8 20.4 0.063 14.0 14.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) NOA36 PF06524.12 ORY48138.1 - 0.94 8.7 17.3 0.27 10.5 13.9 1.7 2 0 0 2 2 2 0 NOA36 protein NPR3 PF03666.13 ORY48138.1 - 3.3 6.4 14.9 4.9 5.8 14.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PPL5 PF18168.1 ORY48138.1 - 3.4 6.9 8.5 5.8 6.1 8.5 1.3 1 0 0 1 1 1 0 Prim-pol family 5 Protocadherin PF08374.11 ORY48138.1 - 5.4 6.9 6.9 10 6.0 6.9 1.4 1 0 0 1 1 1 0 Protocadherin Presenilin PF01080.17 ORY48138.1 - 7.2 5.3 8.3 10 4.7 8.3 1.1 1 0 0 1 1 1 0 Presenilin DUF4436 PF14494.6 ORY48139.1 - 0.00097 18.5 0.1 0.0027 17.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) DUF4020 PF13212.6 ORY48139.1 - 0.18 11.6 0.6 0.33 10.8 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) DUF5421 PF17458.2 ORY48139.1 - 8.1 5.7 8.5 0.13 11.6 1.4 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5421) Ank_2 PF12796.7 ORY48140.1 - 1.8e-36 124.6 0.0 4e-12 46.6 0.0 5.3 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY48140.1 - 1.1e-26 92.8 6.4 4.7e-06 27.0 0.1 7.7 3 2 7 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY48140.1 - 4.2e-22 75.8 6.4 0.083 13.5 0.1 11.2 10 1 1 11 11 11 5 Ankyrin repeat Ank PF00023.30 ORY48140.1 - 7.9e-16 57.7 6.0 2.8 8.6 0.0 9.8 6 3 4 10 10 10 5 Ankyrin repeat Ank_5 PF13857.6 ORY48140.1 - 3.4e-14 52.7 9.3 0.53 10.7 0.1 9.6 2 1 8 10 10 10 4 Ankyrin repeats (many copies) F-box PF00646.33 ORY48140.1 - 0.0023 17.7 0.8 0.0089 15.9 0.2 2.3 2 0 0 2 2 2 1 F-box domain ABC_tran PF00005.27 ORY48141.1 - 6.4e-51 172.5 0.7 1.5e-27 96.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORY48141.1 - 5.4e-36 124.7 37.6 3.5e-27 95.8 18.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 ORY48141.1 - 8.5e-13 48.8 0.3 0.061 13.1 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY48141.1 - 6.1e-10 38.9 7.2 2e-05 24.1 0.7 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY48141.1 - 2.1e-08 34.3 0.0 0.0085 16.2 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY48141.1 - 3.4e-07 29.9 2.2 0.016 14.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY48141.1 - 1.5e-06 28.2 1.6 0.013 15.4 0.3 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 ORY48141.1 - 8.5e-06 26.3 0.1 0.073 13.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain T2SSE PF00437.20 ORY48141.1 - 9.3e-06 24.9 2.8 0.0064 15.6 0.0 3.2 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_7 PF12775.7 ORY48141.1 - 1.7e-05 24.4 0.1 0.12 11.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_23 PF13476.6 ORY48141.1 - 8.7e-05 23.1 1.3 0.41 11.1 0.1 2.6 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 ORY48141.1 - 9.4e-05 22.6 2.7 0.013 15.6 0.2 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_15 PF13175.6 ORY48141.1 - 0.00011 22.1 0.9 0.064 13.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 ORY48141.1 - 0.00011 22.5 1.8 0.48 10.7 0.3 3.4 2 1 0 2 2 2 2 AAA domain TrwB_AAD_bind PF10412.9 ORY48141.1 - 0.00036 19.6 0.2 0.068 12.1 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.18 ORY48141.1 - 0.00042 19.7 0.7 0.22 10.8 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.6 ORY48141.1 - 0.00047 19.8 0.1 0.52 9.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 ORY48141.1 - 0.00048 19.9 0.1 0.18 11.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 ORY48141.1 - 0.00052 20.1 2.2 0.047 13.8 0.2 2.5 2 0 0 2 2 2 1 Dynamin family NB-ARC PF00931.22 ORY48141.1 - 0.0018 17.5 0.3 0.83 8.8 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 ORY48141.1 - 0.0026 17.7 0.5 2.2 8.2 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 ORY48141.1 - 0.0033 18.0 0.2 1.1 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 ORY48141.1 - 0.0036 16.9 0.6 1.4 8.5 0.1 2.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.9 ORY48141.1 - 0.0039 16.0 0.1 0.31 9.8 0.0 2.3 2 0 0 2 2 2 1 Predicted ATPase of the ABC class CoaE PF01121.20 ORY48141.1 - 0.0043 16.8 1.0 0.09 12.4 0.0 2.8 3 0 0 3 3 3 1 Dephospho-CoA kinase AAA_13 PF13166.6 ORY48141.1 - 0.0053 15.5 0.3 0.035 12.8 0.0 2.3 3 0 0 3 3 3 1 AAA domain Roc PF08477.13 ORY48141.1 - 0.0054 16.9 0.2 1.2 9.3 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 ORY48141.1 - 0.0075 16.6 0.0 2.6 8.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.12 ORY48141.1 - 0.0077 15.5 0.3 3.7 6.8 0.1 2.4 2 0 0 2 2 2 1 Zeta toxin MeaB PF03308.16 ORY48141.1 - 0.018 14.0 0.2 1.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 ORY48141.1 - 0.02 14.9 0.7 2.7 8.0 0.0 3.4 3 2 0 3 3 3 0 Type III restriction enzyme, res subunit TsaE PF02367.17 ORY48141.1 - 0.023 14.7 0.1 8.6 6.4 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP-synt_ab PF00006.25 ORY48141.1 - 0.03 14.0 0.1 0.68 9.5 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Ploopntkinase3 PF18751.1 ORY48141.1 - 0.033 14.1 0.1 4.3 7.2 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 ORY48141.1 - 0.043 14.0 0.2 11 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ORY48141.1 - 0.045 13.5 0.1 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORY48141.1 - 0.048 14.0 0.4 9.2 6.6 0.1 2.7 2 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 ORY48141.1 - 0.053 13.3 0.9 2 8.1 0.1 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MobB PF03205.14 ORY48141.1 - 0.06 13.2 0.3 4.4 7.2 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 ORY48141.1 - 0.069 13.1 2.0 1.3 8.9 0.1 3.0 3 0 0 3 3 2 0 NTPase DEAD PF00270.29 ORY48141.1 - 0.073 12.8 0.2 0.62 9.8 0.0 2.4 2 0 0 2 2 2 0 DEAD/DEAH box helicase GTP_EFTU PF00009.27 ORY48141.1 - 0.077 12.5 1.2 13 5.3 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain DUF815 PF05673.13 ORY48141.1 - 0.092 11.9 1.9 12 5.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 ORY48141.1 - 0.1 12.3 0.8 11 5.8 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 ORY48141.1 - 0.11 11.9 0.3 1.7 8.0 0.0 2.8 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI AIG1 PF04548.16 ORY48141.1 - 0.38 10.0 1.8 19 4.5 0.1 2.5 2 0 0 2 2 2 0 AIG1 family dNK PF01712.19 ORY48141.1 - 0.66 9.8 2.4 6.7 6.5 0.2 2.6 2 0 0 2 2 2 0 Deoxynucleoside kinase Amidase_3 PF01520.18 ORY48143.1 - 0.13 12.4 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase MutS_V PF00488.21 ORY48144.1 - 2.1e-67 226.8 0.1 1.1e-66 224.5 0.1 2.1 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 ORY48144.1 - 1.2e-34 120.2 4.6 1.4e-34 120.1 3.1 2.0 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 ORY48144.1 - 5.9e-14 52.3 0.1 2.4e-13 50.3 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.17 ORY48144.1 - 1.6e-10 41.4 0.0 7.5e-10 39.2 0.0 2.1 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 ORY48144.1 - 0.0041 17.4 0.8 0.01 16.1 0.8 1.7 1 0 0 1 1 1 1 MutS family domain IV SUIM_assoc PF16619.5 ORY48144.1 - 0.01 15.9 3.0 0.029 14.4 3.0 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 T2SSF PF00482.23 ORY48144.1 - 0.1 12.5 0.5 1.3 9.0 0.0 2.9 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F CENP-T_C PF15511.6 ORY48145.1 - 2.5e-08 34.0 0.1 3e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 ORY48145.1 - 5.9e-05 23.1 0.1 8.6e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 ORY48145.1 - 0.0001 22.6 0.1 0.00014 22.2 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 ORY48145.1 - 0.0002 21.7 0.2 0.00023 21.6 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY48145.1 - 0.00034 20.8 0.1 0.00068 19.9 0.0 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY48145.1 - 0.02 14.9 0.0 0.023 14.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORY48145.1 - 0.058 13.4 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 ORY48145.1 - 0.17 12.4 0.0 0.34 11.5 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A UPF0137 PF03677.13 ORY48145.1 - 0.2 11.4 0.1 0.24 11.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Histone PF00125.24 ORY48146.1 - 3.5e-52 176.2 1.9 3.9e-52 176.1 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORY48146.1 - 5.2e-05 23.3 0.3 9e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 ORY48146.1 - 6.9e-05 23.2 0.0 0.0001 22.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 ORY48146.1 - 0.00019 22.0 1.2 0.00023 21.8 1.2 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 ORY48146.1 - 0.018 15.3 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY48146.1 - 0.13 12.3 0.1 0.23 11.6 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CCDC92 PF14916.6 ORY48147.1 - 5e-13 48.6 3.6 8.3e-13 47.9 1.7 2.4 2 0 0 2 2 2 1 Coiled-coil domain of unknown function DUF641 PF04859.12 ORY48147.1 - 0.0031 17.9 10.1 0.01 16.2 1.5 2.4 1 1 1 2 2 2 1 Plant protein of unknown function (DUF641) Fungal_TACC PF12709.7 ORY48147.1 - 0.024 15.1 0.5 0.024 15.1 0.5 2.9 2 1 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Not1 PF04054.15 ORY48147.1 - 0.031 13.2 1.4 0.047 12.6 1.4 1.2 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 Gp58 PF07902.11 ORY48147.1 - 0.061 11.6 2.0 0.043 12.1 0.3 1.5 2 0 0 2 2 2 0 gp58-like protein Syntaxin-6_N PF09177.11 ORY48147.1 - 0.065 13.8 4.1 0.65 10.6 0.5 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DivIC PF04977.15 ORY48147.1 - 0.24 11.2 11.0 4 7.3 0.6 3.7 2 1 1 3 3 3 0 Septum formation initiator DUF4407 PF14362.6 ORY48147.1 - 0.33 10.3 9.7 2 7.7 9.9 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YojJ PF10372.9 ORY48147.1 - 0.64 10.2 3.8 6.5 6.9 1.1 2.4 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus DUF1664 PF07889.12 ORY48147.1 - 1.6 8.8 6.5 5.1 7.2 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ADIP PF11559.8 ORY48147.1 - 2.1 8.4 13.2 0.97 9.5 0.7 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 ORY48147.1 - 2.2 8.9 7.2 6.5 7.5 0.4 3.3 2 1 0 2 2 2 0 SlyX Lebercilin PF15619.6 ORY48147.1 - 2.3 7.8 11.7 0.75 9.4 4.1 2.4 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF5595 PF18077.1 ORY48147.1 - 3.1 7.9 5.3 3.6 7.7 0.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5595) ABC_tran_Xtn PF12848.7 ORY48147.1 - 6.2 6.9 12.8 3.9 7.6 0.2 3.7 4 0 0 4 4 4 0 ABC transporter TMPIT PF07851.13 ORY48147.1 - 7.3 5.7 8.7 3.2 6.9 2.4 2.1 2 0 0 2 2 2 0 TMPIT-like protein ERM PF00769.19 ORY48147.1 - 8.2 6.2 13.8 33 4.2 13.8 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Prefoldin PF02996.17 ORY48147.1 - 9.5 6.2 9.3 8.8 6.3 0.7 2.7 2 0 0 2 2 2 0 Prefoldin subunit tRNA-synt_1d PF00750.19 ORY48148.1 - 1.3e-99 333.4 2.6 1.8e-99 333.0 2.6 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 ORY48148.1 - 2.3e-22 79.4 0.3 1.8e-21 76.5 0.0 2.3 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 ORY48148.1 - 0.00063 20.3 0.0 0.0024 18.4 0.0 2.1 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain tRNA-synt_1g PF09334.11 ORY48148.1 - 0.00091 18.1 0.2 1.5 7.5 0.1 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) zf-CCCH PF00642.24 ORY48149.1 - 6.4e-16 57.8 38.5 9.3e-05 22.2 0.6 5.5 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY48149.1 - 1.6e-14 53.4 47.1 2.2e-05 24.4 1.7 6.4 5 1 0 5 5 5 4 Zinc finger domain zf-CCHC PF00098.23 ORY48149.1 - 1.9e-12 46.7 14.9 2e-06 27.6 2.2 3.2 3 0 0 3 3 3 2 Zinc knuckle Torus PF16131.5 ORY48149.1 - 5.4e-12 46.4 30.7 0.00072 20.2 0.7 5.5 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 ORY48149.1 - 3.9e-07 29.7 36.9 4.5e-05 23.1 0.5 5.6 5 1 0 5 5 5 3 CCCH-type zinc finger zf-CCHC_3 PF13917.6 ORY48149.1 - 2.7e-05 24.0 5.8 0.054 13.5 0.1 2.9 2 0 0 2 2 2 2 Zinc knuckle zf-CCCH_3 PF15663.5 ORY48149.1 - 0.0004 20.6 10.2 0.0004 20.6 10.2 3.9 3 1 2 5 5 5 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 ORY48149.1 - 0.0023 18.3 51.5 0.0094 16.4 1.5 7.2 7 0 0 7 7 7 5 RNA-binding, Nab2-type zinc finger zf-CCHC_4 PF14392.6 ORY48149.1 - 1.1 9.1 6.1 4.8 7.0 0.6 2.8 2 0 0 2 2 2 0 Zinc knuckle LUC7 PF03194.15 ORY48149.1 - 9.5 5.8 9.1 19 4.8 1.5 3.1 3 0 0 3 3 3 0 LUC7 N_terminus Baculo_p24 PF05073.12 ORY48150.1 - 0.026 14.3 0.3 0.034 13.9 0.3 1.2 1 0 0 1 1 1 0 Baculovirus P24 capsid protein zf-RING_9 PF13901.6 ORY48150.1 - 0.077 13.0 0.2 0.079 12.9 0.2 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon DUF2408 PF10303.9 ORY48151.1 - 7.7e-05 23.3 0.7 0.00037 21.1 0.8 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2408) Ubiquitin_3 PF14836.6 ORY48151.1 - 0.014 15.3 0.0 0.016 15.2 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain SesA PF17107.5 ORY48151.1 - 0.046 13.9 0.5 4.4 7.5 0.4 2.0 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Baculo_p24 PF05073.12 ORY48151.1 - 0.092 12.5 0.2 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 Baculovirus P24 capsid protein YgaB PF14182.6 ORY48151.1 - 0.12 12.8 2.5 1 9.8 0.2 2.1 2 0 0 2 2 2 0 YgaB-like protein DUF1409 PF07197.12 ORY48151.1 - 7.7 6.5 6.7 25 4.9 2.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1409) Acetyltransf_10 PF13673.7 ORY48152.1 - 4.7e-07 29.8 0.0 1.3e-06 28.4 0.0 1.7 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY48152.1 - 0.00083 19.7 0.0 0.0013 19.1 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY48152.1 - 0.0013 18.9 0.0 0.0021 18.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 ORY48152.1 - 0.13 12.3 0.0 0.72 9.9 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY48153.1 - 4.4e-06 26.7 0.0 7.8e-06 25.8 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY48153.1 - 0.0003 21.0 0.0 0.00039 20.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 ORY48153.1 - 0.00062 19.9 0.0 0.047 13.8 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY48153.1 - 0.0013 19.1 0.0 0.002 18.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Band_7 PF01145.25 ORY48154.1 - 1.3e-12 48.1 3.6 1.9e-11 44.3 1.8 2.8 2 1 0 2 2 2 1 SPFH domain / Band 7 family Hox9_act PF04617.13 ORY48154.1 - 0.022 15.5 0.0 0.045 14.5 0.0 1.5 1 1 0 1 1 1 0 Hox9 activation region Acetyltransf_7 PF13508.7 ORY48155.1 - 3.4e-05 24.2 0.0 5.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY48155.1 - 8.1e-05 22.6 0.0 0.00017 21.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY48155.1 - 0.0047 17.0 0.1 0.34 11.0 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY48155.1 - 0.0099 16.1 0.1 0.017 15.4 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_1 PF00583.25 ORY48156.1 - 0.00012 22.3 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY48156.1 - 0.00012 22.4 0.5 0.00021 21.6 0.5 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY48156.1 - 0.00056 19.8 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 ORY48156.1 - 0.041 13.9 0.1 0.087 12.9 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain CSTF2_hinge PF14327.6 ORY48157.1 - 1.2e-22 80.1 6.3 2.1e-22 79.4 5.1 1.9 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 ORY48157.1 - 3.1e-19 68.5 0.2 5.6e-19 67.7 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 ORY48157.1 - 2.9e-14 52.4 6.9 6.7e-14 51.2 6.9 1.6 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_occluded PF16842.5 ORY48157.1 - 0.057 13.3 0.0 0.17 11.8 0.0 1.8 1 1 0 1 1 1 0 Occluded RNA-recognition motif DUF1866 PF08952.11 ORY48157.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) PIH1 PF08190.12 ORY48158.1 - 1.7e-31 108.9 0.3 2.8e-31 108.2 0.3 1.2 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 ORY48158.1 - 2.7e-08 34.1 0.1 1.7e-07 31.6 0.0 2.0 2 0 0 2 2 2 1 PIH1 CS-like domain NS3_envE PF02723.14 ORY48158.1 - 0.029 14.4 0.9 0.49 10.5 0.1 2.3 2 0 0 2 2 2 0 Non-structural protein NS3/Small envelope protein E Nif11 PF07862.11 ORY48158.1 - 0.14 12.5 1.0 0.26 11.6 1.0 1.5 1 0 0 1 1 1 0 Nif11 domain TPR_MLP1_2 PF07926.12 ORY48159.1 - 0.00017 21.7 51.5 0.016 15.3 20.1 4.4 3 1 1 4 4 4 2 TPR/MLP1/MLP2-like protein Leu_zip PF15294.6 ORY48159.1 - 0.00036 20.1 18.1 0.00036 20.1 18.1 3.2 2 1 1 3 3 3 2 Leucine zipper Adaptin_binding PF10199.9 ORY48159.1 - 0.00075 20.1 14.3 0.54 10.9 0.0 3.4 1 1 1 2 2 2 1 Alpha and gamma adaptin binding protein p34 Spc7 PF08317.11 ORY48159.1 - 0.0011 18.0 46.4 0.015 14.2 10.7 3.1 2 1 1 3 3 3 3 Spc7 kinetochore protein Cnn_1N PF07989.11 ORY48159.1 - 0.0013 18.9 3.1 0.0013 18.9 3.1 5.7 3 1 1 4 4 4 1 Centrosomin N-terminal motif 1 TACC_C PF05010.14 ORY48159.1 - 0.0014 18.5 4.3 0.0014 18.5 4.3 4.2 2 2 1 4 4 4 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Golgin_A5 PF09787.9 ORY48159.1 - 0.0028 17.2 17.2 0.0028 17.2 17.2 2.2 2 0 0 2 2 2 1 Golgin subfamily A member 5 GAS PF13851.6 ORY48159.1 - 0.0033 16.8 47.1 0.23 10.8 15.5 3.7 2 2 1 3 3 3 2 Growth-arrest specific micro-tubule binding DUF1640 PF07798.11 ORY48159.1 - 0.0034 17.4 6.7 0.0034 17.4 6.7 4.3 2 2 1 3 3 3 1 Protein of unknown function (DUF1640) TolA_bind_tri PF16331.5 ORY48159.1 - 0.0066 16.5 26.8 0.02 15.0 4.5 5.8 4 1 1 5 5 5 1 TolA binding protein trimerisation Lebercilin PF15619.6 ORY48159.1 - 0.0067 16.1 43.4 0.3 10.7 14.9 4.2 2 2 1 3 3 3 3 Ciliary protein causing Leber congenital amaurosis disease Tup_N PF08581.10 ORY48159.1 - 0.0083 16.4 4.3 0.0083 16.4 4.3 4.6 4 2 0 4 4 4 1 Tup N-terminal DUF2353 PF09789.9 ORY48159.1 - 0.0099 15.3 31.0 0.31 10.3 4.9 3.0 2 1 0 2 2 2 2 Uncharacterized coiled-coil protein (DUF2353) ADIP PF11559.8 ORY48159.1 - 0.025 14.6 9.3 0.025 14.6 9.3 4.1 2 2 2 4 4 3 0 Afadin- and alpha -actinin-Binding Filament PF00038.21 ORY48159.1 - 0.074 12.6 37.7 0.35 10.4 12.8 3.4 2 1 1 3 3 3 0 Intermediate filament protein DUF4407 PF14362.6 ORY48159.1 - 0.09 12.1 48.0 1.2 8.4 19.1 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) UPF0242 PF06785.11 ORY48159.1 - 0.11 12.6 46.9 5.5 7.0 15.8 3.9 2 2 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 ORY48159.1 - 0.13 12.7 36.3 0.11 13.0 10.1 3.2 2 1 0 2 2 2 0 Fez1 DUF1192 PF06698.11 ORY48159.1 - 0.18 11.9 0.3 0.18 11.9 0.3 5.3 5 1 1 6 6 3 0 Protein of unknown function (DUF1192) FlaC_arch PF05377.11 ORY48159.1 - 0.19 12.1 27.2 3.1 8.3 0.9 6.7 5 2 1 6 6 6 0 Flagella accessory protein C (FlaC) Cob_adeno_trans PF01923.18 ORY48159.1 - 0.2 11.8 22.6 0.37 10.9 5.8 3.2 2 1 0 3 3 3 0 Cobalamin adenosyltransferase ZapB PF06005.12 ORY48159.1 - 0.3 11.6 45.7 0.71 10.4 3.5 5.3 3 1 1 4 4 4 0 Cell division protein ZapB HAP1_N PF04849.13 ORY48159.1 - 0.3 10.2 37.0 0.54 9.4 17.9 3.6 2 2 0 2 2 2 0 HAP1 N-terminal conserved region SOGA PF11365.8 ORY48159.1 - 0.35 12.0 33.6 0.56 11.4 0.5 5.5 3 1 1 5 5 5 0 Protein SOGA CCDC144C PF14915.6 ORY48159.1 - 0.39 9.8 41.9 0.15 11.1 11.1 2.8 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region Uso1_p115_C PF04871.13 ORY48159.1 - 0.45 10.9 56.9 3.2 8.1 13.4 4.3 2 2 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-F_leu_zip PF10473.9 ORY48159.1 - 0.6 10.1 46.7 4.2 7.4 14.0 3.4 2 2 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HOOK PF05622.12 ORY48159.1 - 0.61 8.2 45.1 0.075 11.2 24.2 3.2 2 2 0 2 2 2 0 HOOK protein Shugoshin_N PF07558.11 ORY48159.1 - 0.67 9.9 12.4 13 5.7 0.1 5.4 5 0 0 5 5 5 0 Shugoshin N-terminal coiled-coil region TMF_TATA_bd PF12325.8 ORY48159.1 - 0.83 9.9 42.7 1.4 9.1 4.6 4.5 2 2 2 4 4 4 0 TATA element modulatory factor 1 TATA binding Tropomyosin_1 PF12718.7 ORY48159.1 - 1.1 9.4 51.1 0.31 11.2 2.5 4.8 3 1 1 4 4 4 0 Tropomyosin like DUF5082 PF16888.5 ORY48159.1 - 1.3 9.3 37.5 0.32 11.3 4.3 4.7 2 2 2 5 5 5 0 Domain of unknown function (DUF5082) CASP_C PF08172.12 ORY48159.1 - 1.6 8.0 36.0 0.39 10.0 1.2 3.4 3 0 0 3 3 3 0 CASP C terminal SHE3 PF17078.5 ORY48159.1 - 1.8 8.2 34.5 0.019 14.7 14.8 2.8 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 CorA PF01544.18 ORY48159.1 - 2.4 7.4 22.6 2.8 7.2 8.1 2.6 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein BST2 PF16716.5 ORY48159.1 - 2.5 8.7 44.7 2.4 8.8 0.2 5.6 3 1 1 4 4 4 0 Bone marrow stromal antigen 2 PRKG1_interact PF15898.5 ORY48159.1 - 2.8 8.9 45.9 4.1 8.4 8.2 4.8 2 2 2 4 4 4 0 cGMP-dependent protein kinase interacting domain HrpB7 PF09486.10 ORY48159.1 - 3.3 8.1 37.9 0.047 14.1 8.2 4.7 2 1 4 6 6 6 0 Bacterial type III secretion protein (HrpB7) Erp_C PF06780.11 ORY48159.1 - 3.4 7.7 21.8 0.92 9.5 3.6 3.8 2 2 2 4 4 4 0 Erp protein C-terminus HMMR_N PF15905.5 ORY48159.1 - 3.6 7.0 46.2 0.22 11.0 11.7 3.1 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal PEP-utilisers_N PF05524.13 ORY48159.1 - 4 7.7 22.8 4.8 7.4 2.4 4.5 1 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal ApoO PF09769.9 ORY48159.1 - 4.2 7.4 11.4 4.6 7.2 0.3 3.6 2 1 1 3 3 3 0 Apolipoprotein O CdvA PF18822.1 ORY48159.1 - 4.2 7.2 41.2 0.71 9.7 11.2 5.1 3 1 1 4 4 4 0 CdvA-like coiled-coil domain YabA PF06156.13 ORY48159.1 - 4.7 7.9 39.4 1.9 9.2 4.8 5.5 2 2 1 4 4 3 0 Initiation control protein YabA Cytadhesin_P30 PF07271.11 ORY48159.1 - 5.2 6.6 6.1 1.3 8.5 0.2 2.3 2 0 0 2 2 2 0 Cytadhesin P30/P32 THOC7 PF05615.13 ORY48159.1 - 6.9 7.0 42.2 0.38 11.0 11.3 5.1 2 2 3 5 5 5 0 Tho complex subunit 7 Csm1_N PF18504.1 ORY48159.1 - 8.7 6.8 49.6 0.25 11.7 2.8 6.2 2 2 2 5 5 4 0 Csm1 N-terminal domain Jnk-SapK_ap_N PF09744.9 ORY48159.1 - 9.2 6.5 42.1 3.7 7.8 8.0 3.7 2 2 1 3 3 3 0 JNK_SAPK-associated protein-1 MAD PF05557.13 ORY48159.1 - 9.6 4.4 43.9 1.1 7.5 23.6 2.7 2 2 0 2 2 2 0 Mitotic checkpoint protein Dynactin_p22 PF07426.11 ORY48160.1 - 2.3e-19 69.8 1.0 3.2e-19 69.4 1.0 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 SKA2 PF16740.5 ORY48160.1 - 0.0015 18.3 0.5 0.23 11.3 0.0 3.1 1 1 3 4 4 4 1 Spindle and kinetochore-associated protein 2 Mating_N PF12731.7 ORY48160.1 - 0.0084 16.2 2.7 0.62 10.2 0.2 2.3 2 0 0 2 2 2 2 Mating-type protein beta 1 OSCP PF00213.18 ORY48160.1 - 0.021 14.9 0.6 2.1 8.4 0.0 2.2 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit CheZ PF04344.13 ORY48160.1 - 0.031 14.2 0.2 0.49 10.3 0.0 2.1 2 0 0 2 2 2 0 Chemotaxis phosphatase, CheZ SPACA9 PF15120.6 ORY48160.1 - 0.071 12.9 0.1 0.43 10.3 0.0 2.0 2 0 0 2 2 2 0 Sperm acrosome-associated protein 9 DUF2205 PF10224.9 ORY48160.1 - 0.27 11.3 0.1 0.27 11.3 0.1 2.3 4 0 0 4 4 4 0 Short coiled-coil protein DUF2019 PF09450.10 ORY48161.1 - 0.0091 15.9 0.2 0.046 13.7 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF2019) PH PF00169.29 ORY48161.1 - 0.0091 16.5 0.0 0.016 15.7 0.0 1.3 1 0 0 1 1 1 1 PH domain SUIM_assoc PF16619.5 ORY48162.1 - 0.2 11.8 8.3 0.54 10.4 8.3 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 ORY48162.1 - 0.41 10.6 19.5 0.6 10.0 19.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 ORY48162.1 - 0.75 9.4 10.6 1.3 8.6 10.6 1.5 1 0 0 1 1 1 0 Spt20 family PQ-loop PF04193.14 ORY48163.1 - 2.6e-30 104.0 14.9 2.6e-18 65.5 3.2 2.7 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 ORY48163.1 - 0.094 12.8 6.6 0.092 12.8 0.6 2.5 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Fez1 PF06818.15 ORY48164.1 - 2 8.8 17.4 9 6.7 17.4 2.3 1 1 0 1 1 1 0 Fez1 WW PF00397.26 ORY48165.1 - 0.022 14.8 0.2 0.062 13.4 0.2 1.8 1 0 0 1 1 1 0 WW domain FAD_binding_4 PF01565.23 ORY48166.1 - 0.082 12.6 2.5 0.27 11.0 2.5 1.8 1 0 0 1 1 1 0 FAD binding domain UPF0524 PF15823.5 ORY48166.1 - 4.6 6.6 6.2 3.4 7.0 3.3 2.0 2 0 0 2 2 2 0 UPF0524 of C3orf70 zf-C2H2 PF00096.26 ORY48167.1 - 3.3e-13 49.3 8.8 1.4e-07 31.6 2.4 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY48167.1 - 5.1e-10 39.3 7.5 1.1e-05 25.8 1.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY48167.1 - 9.5e-09 35.3 14.5 1.1e-06 28.8 3.4 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY48167.1 - 0.00023 21.1 9.1 0.0033 17.4 2.2 2.5 2 1 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ORY48167.1 - 0.00044 20.5 3.5 0.011 16.1 1.6 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY48167.1 - 0.0022 18.2 1.4 0.0022 18.2 1.4 2.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-DNA_Pol PF08996.10 ORY48167.1 - 0.006 16.4 1.6 0.0066 16.2 1.6 1.0 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger zf-C2H2_8 PF15909.5 ORY48167.1 - 0.012 15.9 0.4 0.023 15.0 0.4 1.5 1 1 0 1 1 1 0 C2H2-type zinc ribbon zf-C2HE PF16278.5 ORY48167.1 - 0.044 14.2 1.4 0.044 14.2 1.4 2.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 ORY48167.1 - 0.046 13.4 2.7 0.062 13.0 2.0 1.6 1 1 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-LYAR PF08790.11 ORY48167.1 - 0.046 13.6 3.1 0.54 10.2 0.4 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-H2C2_5 PF13909.6 ORY48167.1 - 0.056 13.2 3.4 0.056 13.2 3.4 3.0 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-Di19 PF05605.12 ORY48167.1 - 0.091 13.1 3.5 0.23 11.8 3.5 1.6 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.15 ORY48167.1 - 1 9.4 8.0 1.4 9.0 4.6 2.2 1 1 1 2 2 2 0 BED zinc finger RWD PF05773.22 ORY48169.1 - 2.3e-06 27.9 0.9 0.016 15.5 0.0 2.6 1 1 1 2 2 2 2 RWD domain DFRP_C PF16543.5 ORY48169.1 - 5.7e-06 26.7 11.8 2.3e-05 24.8 11.8 2.2 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 SelB-wing_1 PF09105.10 ORY48169.1 - 0.5 10.4 3.0 6.8 6.7 0.1 2.6 2 0 0 2 2 2 0 Elongation factor SelB, winged helix DUF5401 PF17380.2 ORY48169.1 - 1.4 6.9 12.4 1.8 6.5 12.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Myb_DNA-binding PF00249.31 ORY48170.1 - 4.4e-40 135.6 12.6 3.4e-17 62.4 0.1 4.4 5 0 0 5 5 5 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY48170.1 - 1.9e-35 120.9 5.9 3.6e-15 55.9 0.0 5.0 2 2 3 5 5 5 5 Myb-like DNA-binding domain SLIDE PF09111.10 ORY48170.1 - 6.6e-10 39.0 0.0 0.00026 21.0 0.0 3.2 1 1 2 3 3 3 2 SLIDE Rap1_C PF11626.8 ORY48170.1 - 0.00019 21.5 0.0 0.053 13.6 0.0 2.7 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain XH PF03469.14 ORY48170.1 - 0.005 16.8 0.8 3 7.7 0.1 2.5 2 1 0 2 2 2 2 XH domain MADF_DNA_bdg PF10545.9 ORY48170.1 - 0.01 16.1 2.6 7.2 7.0 0.0 3.3 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_2 PF08914.11 ORY48170.1 - 0.017 15.3 0.0 6.8 7.0 0.0 3.9 4 0 0 4 4 4 0 Rap1 Myb domain HTH_AsnC-type PF13404.6 ORY48170.1 - 0.16 11.8 2.0 0.37 10.6 0.0 2.7 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Myb_DNA-bind_4 PF13837.6 ORY48170.1 - 1.8 9.0 8.3 4.7 7.7 0.2 4.0 4 2 0 4 4 4 0 Myb/SANT-like DNA-binding domain E1-E2_ATPase PF00122.20 ORY48171.1 - 4.9e-53 179.3 0.1 1.2e-52 178.1 0.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY48171.1 - 1e-31 110.0 3.6 1e-31 110.0 3.6 2.4 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 ORY48171.1 - 2.2e-17 62.9 0.0 5e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY48171.1 - 3.3e-13 50.4 0.9 2.8e-08 34.3 0.1 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY48171.1 - 3e-12 46.0 0.0 7.7e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus MFS_1 PF07690.16 ORY48172.1 - 1.7e-19 70.0 45.1 6.7e-12 45.0 22.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY48172.1 - 8e-18 64.5 17.0 9.6e-17 61.0 17.0 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Bim_N PF06773.11 ORY48172.1 - 0.29 10.9 0.7 0.56 9.9 0.7 1.4 1 0 0 1 1 1 0 Bim protein N-terminus IPPT PF01715.17 ORY48173.1 - 4.9e-63 213.0 0.3 7.5e-62 209.1 0.3 2.1 1 1 0 1 1 1 1 IPP transferase IPT PF01745.16 ORY48173.1 - 0.002 17.5 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Isopentenyl transferase AAA_33 PF13671.6 ORY48173.1 - 0.0075 16.4 0.0 0.058 13.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 ORY48173.1 - 0.023 14.5 0.0 0.065 13.0 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF87 PF01935.17 ORY48173.1 - 0.13 12.4 4.8 0.77 9.8 2.8 2.7 2 1 0 2 2 2 0 Helicase HerA, central domain AAA_18 PF13238.6 ORY48173.1 - 0.19 12.3 1.6 2.5 8.6 0.6 2.9 2 1 0 2 2 2 0 AAA domain Mlh1_C PF16413.5 ORY48174.1 - 5.6e-87 291.5 0.1 1.2e-86 290.5 0.1 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 ORY48174.1 - 2.5e-32 111.0 2.2 4.9e-32 110.1 2.2 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 ORY48174.1 - 6.8e-15 55.1 0.1 2.1e-14 53.5 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 ORY48174.1 - 2.3e-08 34.5 0.1 5.2e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Hist_deacetyl PF00850.19 ORY48175.1 - 5e-67 226.5 0.1 5.6e-67 226.4 0.1 1.0 1 0 0 1 1 1 1 Histone deacetylase domain Abhydrolase_1 PF00561.20 ORY48176.1 - 2.9e-14 53.4 0.1 4.7e-14 52.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY48176.1 - 4.2e-14 52.4 0.4 1.2e-13 50.8 0.4 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY48176.1 - 3.8e-13 50.5 2.9 3.8e-13 50.5 2.9 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 ORY48176.1 - 1.2e-05 25.1 0.0 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase LIDHydrolase PF10230.9 ORY48176.1 - 1.6e-05 24.6 0.0 2.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase PGAP1 PF07819.13 ORY48176.1 - 0.00049 19.9 0.0 0.00076 19.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.16 ORY48176.1 - 0.00056 19.8 0.0 0.0059 16.4 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Thioesterase PF00975.20 ORY48176.1 - 0.0098 16.0 0.1 0.015 15.4 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.7 ORY48176.1 - 0.018 14.8 0.1 0.03 14.1 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.18 ORY48176.1 - 0.028 14.0 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Ser_hydrolase PF06821.13 ORY48176.1 - 0.047 13.5 0.4 0.1 12.4 0.4 1.5 1 0 0 1 1 1 0 Serine hydrolase AXE1 PF05448.12 ORY48176.1 - 0.25 10.0 0.1 0.38 9.4 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) zf-NF-X1 PF01422.17 ORY48177.1 - 3.7e-08 33.3 33.7 1.5e-05 25.0 11.9 9.8 12 0 0 12 12 12 4 NF-X1 type zinc finger zf-AN1 PF01428.16 ORY48178.1 - 1.2e-07 31.8 7.6 1.2e-07 31.8 7.6 2.3 2 0 0 2 2 2 1 AN1-like Zinc finger FbpA PF05833.11 ORY48178.1 - 0.068 11.9 3.0 0.099 11.4 3.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF3430 PF11912.8 ORY48179.1 - 0.013 15.6 1.1 0.021 14.9 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3430) AARP2CN PF08142.12 ORY48179.1 - 0.19 11.8 0.1 3.2 7.9 0.0 2.3 2 0 0 2 2 2 0 AARP2CN (NUC121) domain Ank_2 PF12796.7 ORY48180.1 - 1.4e-17 64.0 0.1 4.7e-08 33.5 0.0 4.7 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY48180.1 - 2.6e-13 50.2 1.5 0.0034 17.9 0.0 5.3 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY48180.1 - 1e-10 41.6 8.8 0.068 13.5 0.1 7.8 5 2 5 10 10 10 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY48180.1 - 6.6e-08 32.2 2.1 1.5 9.6 0.0 7.9 9 0 0 9 9 9 2 Ankyrin repeat Ank PF00023.30 ORY48180.1 - 0.00021 21.6 6.0 19 5.9 0.0 6.7 7 1 0 7 7 7 1 Ankyrin repeat F-box-like PF12937.7 ORY48180.1 - 0.059 13.3 0.2 0.19 11.6 0.1 1.9 2 0 0 2 2 2 0 F-box-like Histone PF00125.24 ORY48181.1 - 3.5e-52 176.2 1.9 3.9e-52 176.1 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 ORY48181.1 - 5.2e-05 23.3 0.3 9e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 ORY48181.1 - 6.9e-05 23.2 0.0 0.0001 22.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 ORY48181.1 - 0.00019 22.0 1.2 0.00023 21.8 1.2 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 ORY48181.1 - 0.018 15.3 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY48181.1 - 0.13 12.3 0.1 0.23 11.6 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 ORY48182.1 - 2.5e-08 34.0 0.1 3e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 ORY48182.1 - 5.9e-05 23.1 0.1 8.6e-05 22.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 ORY48182.1 - 0.0001 22.6 0.1 0.00014 22.2 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein Histone PF00125.24 ORY48182.1 - 0.0002 21.7 0.2 0.00023 21.6 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY48182.1 - 0.00034 20.8 0.1 0.00068 19.9 0.0 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY48182.1 - 0.02 14.9 0.0 0.023 14.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORY48182.1 - 0.058 13.4 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID_20kDa PF03847.13 ORY48182.1 - 0.17 12.4 0.0 0.34 11.5 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A UPF0137 PF03677.13 ORY48182.1 - 0.2 11.4 0.1 0.24 11.2 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) Sedlin_N PF04628.13 ORY48183.1 - 3.1e-44 150.3 0.2 3.5e-44 150.1 0.2 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 ORY48183.1 - 8.9e-08 32.2 0.1 2.1e-07 31.0 0.1 1.7 1 1 0 1 1 1 1 Sybindin-like family RPN7 PF10602.9 ORY48184.1 - 2.2e-53 180.5 0.6 3.3e-53 179.9 0.6 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 ORY48184.1 - 4.4e-16 59.3 0.1 1.4e-15 57.7 0.1 1.9 2 0 0 2 2 2 1 PCI domain TPR_8 PF13181.6 ORY48184.1 - 9.1 6.8 6.8 13 6.3 0.7 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Fe_hyd_lg_C PF02906.14 ORY48185.1 - 1.1e-70 238.0 0.0 1.5e-70 237.6 0.0 1.1 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain FAD_syn PF06574.12 ORY48185.1 - 0.0013 18.6 0.0 0.0037 17.2 0.0 1.7 2 0 0 2 2 2 1 FAD synthetase Peptidase_M1 PF01433.20 ORY48186.1 - 4.2e-57 193.2 0.0 7.7e-57 192.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 ORY48186.1 - 4.8e-32 111.7 0.0 7.4e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Aminopep PF10023.9 ORY48186.1 - 0.044 13.2 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Putative aminopeptidase Viral_protease PF08715.10 ORY48186.1 - 0.15 11.4 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 Papain like viral protease Ribosomal_L17 PF01196.19 ORY48187.1 - 0.00032 21.5 0.6 0.00082 20.2 0.0 2.0 2 1 0 2 2 2 1 Ribosomal protein L17 Glyco_hydro_15 PF00723.21 ORY48188.1 - 1.4e-40 139.4 0.8 6.3e-30 104.3 0.0 3.3 2 1 1 3 3 3 3 Glycosyl hydrolases family 15 tRNA_bind PF01588.20 ORY48188.1 - 1.1e-30 105.5 0.2 2e-30 104.7 0.2 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 ORY48188.1 - 6.5e-06 26.1 0.5 2.7e-05 24.1 0.5 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY48188.1 - 6.9e-05 23.0 0.5 6.9e-05 23.0 0.5 2.5 2 2 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY48188.1 - 0.00045 20.4 0.1 0.00045 20.4 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 ORY48188.1 - 0.0068 16.2 0.3 0.019 14.8 0.3 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GAGA_bind PF06217.12 ORY48188.1 - 0.087 13.1 2.0 0.18 12.0 2.0 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 ORY48188.1 - 0.44 10.3 7.5 0.77 9.5 7.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 ORY48188.1 - 2 8.8 6.8 4.9 7.6 6.8 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 Ank_2 PF12796.7 ORY48189.1 - 5.2e-22 78.2 1.7 2.8e-11 43.9 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY48189.1 - 2.2e-21 75.9 3.3 7e-08 32.9 0.0 4.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY48189.1 - 1.3e-18 66.8 1.7 1.8e-07 31.3 0.1 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY48189.1 - 7.3e-16 56.7 0.4 0.18 12.5 0.0 7.0 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 ORY48189.1 - 3.1e-14 52.7 0.8 0.025 15.0 0.0 6.6 6 0 0 6 6 6 3 Ankyrin repeat FERM_f0 PF16511.5 ORY48189.1 - 0.0071 16.6 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM AAA_18 PF13238.6 ORY48190.1 - 0.00027 21.5 0.1 0.001 19.6 0.0 1.9 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 ORY48190.1 - 0.00061 19.8 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 ORY48190.1 - 0.0014 18.0 0.0 0.0028 17.0 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 ORY48190.1 - 0.0023 18.4 0.1 0.0076 16.7 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 ORY48190.1 - 0.0026 17.8 0.0 0.0045 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.14 ORY48190.1 - 0.006 16.5 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 ORY48190.1 - 0.012 15.7 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 ORY48190.1 - 0.014 14.4 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PRK PF00485.18 ORY48190.1 - 0.016 15.0 0.1 0.37 10.5 0.1 2.2 1 1 1 2 2 2 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 ORY48190.1 - 0.016 14.4 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain cobW PF02492.19 ORY48190.1 - 0.019 14.6 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 ORY48190.1 - 0.042 14.1 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 ORY48190.1 - 0.057 12.6 0.0 0.072 12.3 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain SRP54 PF00448.22 ORY48190.1 - 0.057 13.0 0.0 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 ORY48190.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 NTPase CbiA PF01656.23 ORY48190.1 - 0.073 13.1 0.1 0.11 12.6 0.1 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.29 ORY48190.1 - 0.079 13.4 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF463 PF04317.12 ORY48190.1 - 0.079 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 RNA_helicase PF00910.22 ORY48190.1 - 0.085 13.3 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 ORY48190.1 - 0.092 13.3 0.0 0.26 11.8 0.0 1.7 2 0 0 2 2 2 0 ABC transporter AAA_28 PF13521.6 ORY48190.1 - 0.13 12.5 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arm PF00514.23 ORY48191.1 - 0.0011 19.0 0.7 27 5.0 0.0 4.8 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Cbl_N PF02262.16 ORY48191.1 - 0.034 14.2 0.1 0.17 11.9 0.0 2.2 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 DUF1764 PF08576.10 ORY48191.1 - 4.5 8.2 0.0 4.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF5065 PF16723.5 ORY48192.1 - 0.07 13.2 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5065) SKG6 PF08693.10 ORY48193.1 - 9.6 5.7 7.4 20 4.7 7.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MatE PF01554.18 ORY48194.1 - 3.8e-49 166.4 37.2 6.3e-29 100.7 7.7 3.4 4 0 0 4 4 4 3 MatE ZZ PF00569.17 ORY48195.1 - 2.4e-35 120.1 30.9 8.7e-13 47.9 4.8 3.3 3 0 0 3 3 3 3 Zinc finger, ZZ type C1_2 PF03107.16 ORY48195.1 - 3.9e-12 46.3 32.0 2.9e-05 24.3 4.7 3.6 3 0 0 3 3 3 3 C1 domain MgtE PF01769.16 ORY48196.1 - 3.8e-36 124.2 32.6 2.2e-19 70.1 5.9 3.2 3 0 0 3 3 3 2 Divalent cation transporter DUF4181 PF13789.6 ORY48196.1 - 0.24 11.7 5.8 1.2 9.4 2.2 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4181) Lyase_aromatic PF00221.19 ORY48197.1 - 2.4e-192 639.7 0.2 2.8e-192 639.5 0.2 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Amidohydro_1 PF01979.20 ORY48198.1 - 3.1e-17 62.9 1.7 7.6e-17 61.6 1.7 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY48198.1 - 1.3e-15 57.9 2.7 1.8e-10 40.9 0.1 2.4 1 1 0 2 2 2 2 Amidohydrolase family Arginase PF00491.21 ORY48199.1 - 5.8e-40 137.5 0.0 7e-40 137.3 0.0 1.1 1 0 0 1 1 1 1 Arginase family Urocanase_C PF17392.2 ORY48200.1 - 1e-62 211.1 0.9 1.5e-46 158.3 1.6 2.3 1 1 1 2 2 2 2 Urocanase C-terminal domain Urocanase_N PF17391.2 ORY48200.1 - 4.1e-54 181.7 0.2 1.3e-53 180.0 0.2 1.8 2 0 0 2 2 2 1 Urocanase N-terminal domain Urocanase PF01175.18 ORY48200.1 - 3.1e-51 174.0 2.7 1.7e-38 132.4 0.0 3.2 1 1 2 3 3 3 3 Urocanase Rossmann-like domain Sacchrp_dh_C PF16653.5 ORY48201.1 - 1.2e-91 307.5 0.0 4.4e-91 305.7 0.0 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 ORY48201.1 - 9.5e-25 87.5 0.0 2.1e-24 86.3 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 ORY48201.1 - 1.3e-19 70.7 0.0 7.3e-19 68.3 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 ORY48201.1 - 2.9e-06 26.8 0.0 0.0018 17.6 0.0 3.3 3 1 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_10 PF13460.6 ORY48201.1 - 6.4e-05 22.9 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 ORY48201.1 - 0.00072 19.6 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.24 ORY48201.1 - 0.019 15.4 0.0 0.056 13.9 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain GPP34 PF05719.11 ORY48201.1 - 0.037 14.1 0.1 0.35 10.9 0.0 2.3 2 0 0 2 2 2 0 Golgi phosphoprotein 3 (GPP34) Flavin_Reduct PF01613.18 ORY48202.1 - 2.4e-13 50.4 1.3 3.1e-12 46.8 1.3 2.0 1 1 0 1 1 1 1 Flavin reductase like domain TMEM191C PF15194.6 ORY48204.1 - 0.22 11.7 1.3 0.26 11.5 0.2 1.7 2 0 0 2 2 2 0 TMEM191C family Pkinase PF00069.25 ORY48205.1 - 8.5e-45 153.2 0.0 1.7e-43 148.9 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY48205.1 - 1.3e-25 90.2 0.0 2.1e-24 86.2 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY48205.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ORY48205.1 - 0.18 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 PIP5K PF01504.18 ORY48206.1 - 1.4e-46 159.0 0.0 5.9e-44 150.3 0.0 3.0 2 1 0 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Pkinase PF00069.25 ORY48207.1 - 4.1e-68 229.6 0.0 1.2e-67 228.1 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY48207.1 - 3.9e-34 118.1 0.0 5.5e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY48207.1 - 0.029 13.7 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 ORY48207.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY48207.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pex24p PF06398.11 ORY48208.1 - 0.017 14.2 0.6 0.026 13.5 0.6 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Peptidase_M1_N PF17900.1 ORY48209.1 - 5.9e-50 170.0 2.1 1.3e-49 168.9 1.3 2.0 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 ORY48209.1 - 1.9e-38 132.3 0.2 8.8e-27 94.1 0.1 3.3 1 1 2 3 3 3 3 Peptidase family M1 domain ERAP1_C PF11838.8 ORY48209.1 - 3.9e-19 69.3 0.2 9.9e-06 25.3 0.0 4.4 2 1 2 4 4 4 3 ERAP1-like C-terminal domain DUF2808 PF10989.8 ORY48209.1 - 0.002 18.1 0.1 0.0048 16.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) TPR_2 PF07719.17 ORY48210.1 - 5.4e-21 73.0 5.0 1.8e-07 30.7 0.0 4.9 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 ORY48210.1 - 1e-18 66.3 10.6 1.8e-08 33.8 0.4 5.2 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY48210.1 - 9.3e-17 59.8 8.1 3.2e-05 23.8 0.1 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY48210.1 - 4.5e-15 56.0 0.0 2.3e-06 28.2 0.0 3.3 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY48210.1 - 2.1e-14 52.8 2.4 0.0013 19.0 0.2 4.1 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORY48210.1 - 6.2e-14 52.0 0.7 1.3e-06 28.6 0.0 3.4 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORY48210.1 - 6.6e-14 51.3 11.7 1.8e-05 24.3 0.1 4.3 2 2 2 4 4 4 4 TPR repeat TPR_14 PF13428.6 ORY48210.1 - 1.5e-11 44.1 0.1 0.049 14.5 0.0 4.5 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.6 ORY48210.1 - 2.4e-11 44.0 2.1 3.1e-05 24.4 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY48210.1 - 5.8e-11 42.3 0.0 0.092 13.4 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY48210.1 - 9.2e-07 28.5 1.5 0.0079 16.0 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY48210.1 - 3.1e-06 26.8 0.7 0.38 10.9 0.0 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY48210.1 - 0.00011 22.4 0.6 0.0071 16.6 1.0 2.2 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_5 PF12688.7 ORY48210.1 - 0.0012 19.0 0.0 0.028 14.7 0.0 2.2 2 0 0 2 2 2 1 Tetratrico peptide repeat TPR_9 PF13371.6 ORY48210.1 - 0.0034 17.5 0.0 1.9 8.7 0.0 3.0 1 1 3 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 ORY48210.1 - 0.0085 15.3 0.1 0.018 14.3 0.0 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_20 PF14561.6 ORY48210.1 - 0.013 15.8 0.1 5 7.5 0.0 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat DUF3856 PF12968.7 ORY48210.1 - 0.024 14.7 0.0 0.13 12.3 0.0 1.9 1 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_4 PF07721.14 ORY48210.1 - 0.03 14.9 0.0 54 4.8 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 ORY48210.1 - 0.059 13.4 0.3 0.059 13.4 0.3 3.1 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain PPR PF01535.20 ORY48210.1 - 0.18 12.1 3.7 1.8 9.0 0.2 3.1 3 0 0 3 3 3 0 PPR repeat SNAP PF14938.6 ORY48210.1 - 0.31 10.4 3.5 1.2 8.5 3.5 1.9 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP ETF_QO PF05187.13 ORY48211.1 - 1.4e-33 115.1 0.9 2.6e-33 114.3 0.9 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Thi4 PF01946.17 ORY48211.1 - 2.1e-05 23.9 0.0 0.00051 19.4 0.0 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 ORY48211.1 - 2.5e-05 23.6 0.0 0.0017 17.5 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 ORY48211.1 - 2.5e-05 24.3 0.0 4.4e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.24 ORY48211.1 - 2.8e-05 23.9 0.0 0.0075 15.9 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY48211.1 - 4.8e-05 22.7 0.0 7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY48211.1 - 0.00031 20.9 0.0 0.00093 19.4 0.0 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Fer4_7 PF12838.7 ORY48211.1 - 0.001 19.6 0.8 0.0027 18.2 0.8 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain FAD_binding_3 PF01494.19 ORY48211.1 - 0.0016 17.8 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 ORY48211.1 - 0.0022 16.8 0.0 0.0041 15.9 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 ORY48211.1 - 0.0027 17.0 0.0 0.0039 16.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 ORY48211.1 - 0.004 16.3 0.0 0.0056 15.8 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 ORY48211.1 - 0.0048 17.4 0.0 4.8 7.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY48211.1 - 0.03 13.2 0.0 0.5 9.2 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Fer4_10 PF13237.6 ORY48211.1 - 0.1 12.7 1.5 0.34 11.1 1.5 1.7 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 ORY48211.1 - 0.14 12.3 0.7 0.57 10.4 0.7 2.0 1 0 0 1 1 1 0 4Fe-4S binding domain FAD_oxidored PF12831.7 ORY48211.1 - 0.15 11.4 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 ORY48211.1 - 0.24 10.5 0.0 0.34 9.9 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pkinase PF00069.25 ORY48212.1 - 1.6e-61 208.0 0.0 1.9e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY48212.1 - 7.7e-30 104.0 0.0 9.9e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY48212.1 - 0.00013 21.1 0.0 0.00019 20.5 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY48212.1 - 0.00022 20.6 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY48212.1 - 0.0088 16.0 0.1 0.09 12.7 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORY48212.1 - 0.15 11.6 0.0 0.4 10.3 0.0 1.7 1 0 0 1 1 1 0 RIO1 family zf-RING_2 PF13639.6 ORY48214.1 - 7.2e-07 29.5 8.8 9.4e-07 29.1 7.8 1.8 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.7 ORY48214.1 - 5e-06 26.7 8.2 9.9e-06 25.8 8.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORY48214.1 - 0.0007 19.4 8.7 0.0014 18.5 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY48214.1 - 0.00079 19.1 3.5 0.0029 17.3 2.7 2.3 2 1 0 2 2 1 1 RING-like zinc finger zf-RING_5 PF14634.6 ORY48214.1 - 0.001 19.0 8.0 0.0018 18.2 8.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY48214.1 - 0.0029 17.6 2.1 0.0029 17.6 2.1 2.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 ORY48214.1 - 0.0063 16.5 3.0 0.012 15.6 3.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UDP PF14569.6 ORY48214.1 - 0.0076 16.3 1.9 0.014 15.5 1.9 1.4 1 0 0 1 1 1 1 Zinc-binding RING-finger zf-Di19 PF05605.12 ORY48214.1 - 0.0099 16.2 1.8 0.16 12.3 0.4 2.5 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_2 PF13923.6 ORY48214.1 - 0.01 15.7 8.0 0.038 13.8 8.0 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 ORY48214.1 - 0.09 13.0 7.8 2.1 8.6 7.8 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 ORY48214.1 - 0.1 12.5 5.4 0.3 11.0 5.4 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 ORY48214.1 - 0.13 12.1 7.2 0.42 10.5 7.3 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 ORY48214.1 - 0.21 11.6 3.3 0.55 10.3 3.3 1.7 1 0 0 1 1 1 0 Double zinc ribbon LrgA PF03788.14 ORY48214.1 - 0.33 10.9 2.9 2.2 8.3 0.9 2.5 2 0 0 2 2 2 0 LrgA family Zn_ribbon_17 PF17120.5 ORY48214.1 - 0.43 10.2 5.9 0.92 9.2 5.9 1.5 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Ycf4 PF02392.16 ORY48214.1 - 1.8 8.1 5.3 0.56 9.7 2.3 1.6 2 0 0 2 2 2 0 Ycf4 Peptidase_M1 PF01433.20 ORY48215.1 - 2.6e-71 239.6 5.5 7.7e-53 179.3 2.4 2.5 1 1 1 2 2 2 2 Peptidase family M1 domain Peptidase_M1_N PF17900.1 ORY48215.1 - 5.9e-49 166.8 1.4 9.9e-49 166.0 0.8 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 ORY48215.1 - 7.1e-39 134.2 0.1 2.1e-25 90.0 0.0 2.4 1 1 1 2 2 2 2 ERAP1-like C-terminal domain DUF2808 PF10989.8 ORY48215.1 - 0.0023 18.0 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) Aminopep PF10023.9 ORY48215.1 - 0.02 14.3 0.1 0.035 13.5 0.1 1.3 1 0 0 1 1 1 0 Putative aminopeptidase TerD PF02342.18 ORY48216.1 - 4.3e-11 42.7 0.0 1.8e-08 34.1 0.0 2.5 2 0 0 2 2 2 2 TerD domain F-box-like PF12937.7 ORY48216.1 - 2.2e-07 30.6 0.1 5e-07 29.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY48216.1 - 0.00011 21.9 0.0 0.00036 20.3 0.0 1.9 2 0 0 2 2 2 1 F-box domain VWA_2 PF13519.6 ORY48216.1 - 0.00028 21.5 0.0 0.001 19.7 0.0 2.0 1 1 1 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 ORY48216.1 - 0.028 14.7 0.0 0.07 13.4 0.0 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain Peptidase_M1 PF01433.20 ORY48217.1 - 5.8e-84 281.0 1.7 1e-83 280.2 1.7 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 ORY48217.1 - 6.4e-47 160.2 1.4 3e-46 158.0 1.0 2.1 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 ORY48217.1 - 2.8e-43 148.7 5.5 3.2e-43 148.5 1.5 2.7 2 1 0 2 2 2 1 ERAP1-like C-terminal domain DUF2808 PF10989.8 ORY48217.1 - 0.027 14.4 0.1 0.059 13.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) DUF3458 PF11940.8 ORY48217.1 - 0.073 13.5 0.0 0.93 10.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3458) Ig-like fold Aminopep PF10023.9 ORY48217.1 - 0.075 12.4 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Putative aminopeptidase TraE PF05309.11 ORY48217.1 - 0.15 11.4 1.4 0.44 9.9 0.0 2.4 4 0 0 4 4 4 0 TraE protein Ogr_Delta PF04606.12 ORY48217.1 - 0.19 11.8 0.3 0.65 10.0 0.3 1.9 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger B_solenoid_ydck PF18836.1 ORY48219.1 - 0.083 12.8 0.3 0.2 11.6 0.3 1.6 1 0 0 1 1 1 0 Beta solenoid repeat from YDCK PAP2_C PF14360.6 ORY48220.1 - 7.6e-12 45.6 4.3 7.6e-12 45.6 4.3 2.5 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2 PF01569.21 ORY48220.1 - 1.9e-05 24.4 2.7 1.9e-05 24.4 2.7 2.1 2 0 0 2 2 2 1 PAP2 superfamily ASH PF15780.5 ORY48221.1 - 1.3e-19 70.2 22.7 0.00077 19.6 0.2 12.7 13 2 1 14 14 14 5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 ORY48221.1 - 4.9e-08 32.8 9.8 0.2 11.5 0.0 8.0 9 0 0 9 9 9 3 MSP (Major sperm protein) domain TMEM131_like PF12371.8 ORY48221.1 - 8.8e-06 25.9 14.4 0.076 13.3 0.0 7.9 8 1 1 9 9 9 3 Transmembrane protein 131-like Transglut_C PF00927.22 ORY48221.1 - 0.017 15.2 0.9 44 4.3 0.0 5.2 5 0 0 5 5 5 0 Transglutaminase family, C-terminal ig like domain GDE_N_bis PF14742.6 ORY48221.1 - 1.3 8.6 3.3 24 4.4 0.0 4.4 6 0 0 6 6 6 0 N-terminal domain of (some) glycogen debranching enzymes CoA_binding_2 PF13380.6 ORY48222.1 - 3.5e-31 108.1 0.0 4.3e-31 107.8 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain Corona_NS4 PF03905.13 ORY48222.1 - 0.055 13.5 0.1 0.16 12.0 0.1 1.8 1 0 0 1 1 1 0 Coronavirus non-structural protein NS4 UDG PF03167.19 ORY48223.1 - 6.7e-17 61.9 0.0 1.7e-16 60.5 0.0 1.7 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily RRN3 PF05327.11 ORY48223.1 - 0.15 10.6 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ribosomal_L7Ae PF01248.26 ORY48224.1 - 2.5e-23 81.6 0.9 5.1e-23 80.6 0.6 1.7 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family TMEM18 PF14770.6 ORY48225.1 - 4.4e-19 68.6 0.2 5.4e-19 68.3 0.2 1.1 1 0 0 1 1 1 1 Transmembrane protein 18 DUF3124 PF11322.8 ORY48225.1 - 0.069 13.4 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3124) TBD PF12845.7 ORY48225.1 - 0.15 12.0 0.2 0.22 11.4 0.2 1.2 1 0 0 1 1 1 0 TBD domain Maf PF02545.14 ORY48226.1 - 2.8e-31 108.6 0.0 3.2e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein HK97-gp10_like PF04883.12 ORY48227.1 - 0.023 15.7 1.0 0.09 13.8 0.1 2.4 3 0 0 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component RNB PF00773.19 ORY48228.1 - 5e-65 220.0 0.0 7.5e-65 219.4 0.0 1.2 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 ORY48228.1 - 3.3e-22 78.3 0.0 7.3e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 ORY48228.1 - 1.4e-15 57.3 0.0 3.5e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain PIN_4 PF13638.6 ORY48228.1 - 7.8e-13 48.8 0.0 1.8e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 PIN domain Rrp44_S1 PF17215.3 ORY48228.1 - 2.1e-11 43.6 3.8 1.6e-09 37.6 3.8 2.6 1 1 0 1 1 1 1 S1 domain CSD2 PF17876.1 ORY48228.1 - 3.9e-08 33.4 1.4 1.8e-05 24.8 0.0 3.4 3 1 0 3 3 3 2 Cold shock domain Dis3l2_C_term PF17877.1 ORY48228.1 - 0.015 15.6 0.0 0.036 14.4 0.0 1.6 1 0 0 1 1 1 0 DIS3-like exonuclease 2 C terminal OB_RNB PF08206.11 ORY48228.1 - 0.061 13.0 0.1 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease B OB domain TPR_12 PF13424.6 ORY48229.1 - 8.9e-38 128.4 9.9 3.7e-18 65.6 0.1 6.0 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 ORY48229.1 - 2.6e-28 97.1 6.8 3.5e-07 29.9 0.0 8.8 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_1 PF00515.28 ORY48229.1 - 2.3e-14 52.5 12.1 0.013 15.3 0.1 7.2 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 ORY48229.1 - 1.9e-13 49.4 15.5 0.0071 16.3 0.0 7.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORY48229.1 - 1.5e-11 43.5 13.0 0.0072 16.4 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY48229.1 - 1e-09 37.8 15.3 0.032 14.4 0.0 6.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY48229.1 - 1.8e-09 37.5 0.4 1.8e-05 24.3 0.0 3.0 3 0 0 3 3 3 2 MalT-like TPR region TPR_4 PF07721.14 ORY48229.1 - 1e-07 31.9 1.2 0.021 15.4 0.1 4.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY48229.1 - 1e-07 32.4 7.6 0.0025 18.3 0.0 5.7 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY48229.1 - 1.2e-06 29.0 5.3 0.5 11.1 0.1 5.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY48229.1 - 2.3e-06 27.9 11.1 0.88 10.6 0.0 6.8 8 0 0 8 8 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY48229.1 - 3.1e-06 27.3 5.9 0.62 10.3 0.0 5.6 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 ORY48229.1 - 6.9e-06 26.0 1.9 0.46 10.9 0.0 5.3 4 0 0 4 4 4 1 PPR repeat TPR_17 PF13431.6 ORY48229.1 - 0.00048 20.3 0.2 5.6 7.6 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat MIT PF04212.18 ORY48229.1 - 0.017 15.2 0.0 0.55 10.3 0.0 3.4 3 0 0 3 3 2 0 MIT (microtubule interacting and transport) domain RPN6_N PF18055.1 ORY48229.1 - 0.022 15.1 0.7 4.9 7.6 0.1 4.2 4 1 1 5 5 5 0 26S proteasome regulatory subunit RPN6 N-terminal domain PPR_2 PF13041.6 ORY48229.1 - 0.05 13.8 0.1 45 4.4 0.0 4.2 4 0 0 4 4 4 0 PPR repeat family TPR_6 PF13174.6 ORY48229.1 - 0.093 13.4 11.0 60 4.6 0.0 7.0 8 0 0 8 8 7 0 Tetratricopeptide repeat DUF1897 PF09005.10 ORY48229.1 - 0.1 12.1 0.1 32 4.1 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1897) TPR_11 PF13414.6 ORY48229.1 - 0.17 11.6 4.9 50 3.7 0.0 4.7 5 0 0 5 5 5 0 TPR repeat V_ATPase_I PF01496.19 ORY48231.1 - 2.4e-218 727.0 11.8 2.2e-123 412.9 6.1 2.0 1 1 1 2 2 2 2 V-type ATPase 116kDa subunit family DUF1515 PF07439.11 ORY48231.1 - 0.015 15.3 1.4 0.042 13.9 1.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) DUF4349 PF14257.6 ORY48231.1 - 0.026 14.0 4.5 0.55 9.6 1.7 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4349) SlyX PF04102.12 ORY48231.1 - 0.032 14.8 2.3 2 9.1 1.1 2.5 2 0 0 2 2 2 0 SlyX CCDC-167 PF15188.6 ORY48231.1 - 0.093 13.1 5.4 0.22 11.9 5.4 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Med9 PF07544.13 ORY48231.1 - 0.096 12.8 1.7 0.21 11.7 1.1 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF641 PF04859.12 ORY48231.1 - 0.21 11.9 3.2 0.41 11.0 3.2 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) ABC_tran_CTD PF16326.5 ORY48231.1 - 0.4 11.0 2.5 1.2 9.4 2.5 1.8 1 0 0 1 1 1 0 ABC transporter C-terminal domain FapA PF03961.13 ORY48231.1 - 0.43 9.1 2.7 1.9 7.0 1.7 2.0 2 0 0 2 2 2 0 Flagellar Assembly Protein A DUF2730 PF10805.8 ORY48231.1 - 0.79 9.9 6.9 5.5 7.1 1.2 3.5 3 1 1 4 4 3 0 Protein of unknown function (DUF2730) FlaC_arch PF05377.11 ORY48231.1 - 3 8.3 4.4 4 7.9 1.1 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 ORY48231.1 - 3 8.0 5.9 0.33 11.1 1.2 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Cyclin PF08613.11 ORY48233.1 - 1.1e-09 38.9 0.3 1.8e-09 38.2 0.3 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY48233.1 - 2.2e-08 33.9 0.2 4.1e-08 33.0 0.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain FOP_dimer PF09398.10 ORY48234.1 - 1.8e-12 47.3 0.7 4.1e-12 46.2 0.2 1.8 2 0 0 2 2 2 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 ORY48234.1 - 8.7e-06 24.7 0.7 6.3e-05 21.9 0.7 2.1 2 0 0 2 2 2 1 LisH Securin PF04856.13 ORY48234.1 - 0.012 15.6 0.1 0.013 15.5 0.1 1.3 1 1 0 1 1 1 0 Securin sister-chromatid separation inhibitor Acetyltransf_16 PF05301.11 ORY48235.1 - 1.8e-52 177.6 0.1 5.8e-43 146.7 0.1 2.2 2 0 0 2 2 2 2 GNAT acetyltransferase, Mec-17 Rad21_Rec8_N PF04825.13 ORY48236.1 - 5.1e-37 126.4 0.0 6.3e-37 126.1 0.0 1.1 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Chisel PF15355.6 ORY48236.1 - 0.21 11.8 0.2 1.8 8.9 0.0 2.3 2 1 0 2 2 2 0 Stretch-responsive small skeletal muscle X protein, Chisel CRISPR_Cse1 PF09481.10 ORY48237.1 - 0.033 13.3 0.3 0.59 9.2 0.0 2.0 1 1 1 2 2 2 0 CRISPR-associated protein Cse1 (CRISPR_cse1) PPR PF01535.20 ORY48237.1 - 0.078 13.3 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 PPR repeat Cas_DxTHG PF09455.10 ORY48237.1 - 0.19 11.3 0.0 0.24 10.9 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family NAC PF01849.18 ORY48239.1 - 1.7e-18 66.3 0.1 2.7e-18 65.7 0.1 1.3 1 0 0 1 1 1 1 NAC domain PEPCK_N PF17297.2 ORY48239.1 - 0.011 15.4 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase N-terminal domain DUF3153 PF11353.8 ORY48239.1 - 0.12 12.0 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) zf-C2H2 PF00096.26 ORY48240.1 - 1.1e-10 41.3 4.4 0.0002 21.6 0.0 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY48240.1 - 1.1e-05 25.8 5.0 0.012 16.3 0.7 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY48240.1 - 0.00038 20.7 0.1 0.00038 20.7 0.1 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 ORY48240.1 - 0.00099 19.4 0.4 0.0048 17.2 0.2 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.6 ORY48240.1 - 0.0058 16.3 2.4 2 8.3 0.3 2.2 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 ORY48240.1 - 0.031 15.0 0.1 0.04 14.6 0.1 1.1 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 ORY48240.1 - 0.033 14.5 0.7 0.082 13.2 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 ORY48240.1 - 0.039 13.7 0.2 0.039 13.7 0.2 2.0 2 0 0 2 2 2 0 zinc-finger C2H2-type SpdB PF05122.13 ORY48240.1 - 0.043 13.9 0.1 0.093 12.9 0.1 1.5 1 0 0 1 1 1 0 Mobile element transfer protein Ogr_Delta PF04606.12 ORY48240.1 - 0.11 12.5 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger zf-BED PF02892.15 ORY48240.1 - 0.82 9.7 3.3 12 6.0 0.1 2.3 2 0 0 2 2 2 0 BED zinc finger Las1 PF04031.13 ORY48242.1 - 4.5e-46 156.7 0.4 8.2e-46 155.9 0.4 1.4 1 0 0 1 1 1 1 Las1-like ApbA_C PF08546.11 ORY48243.1 - 8.3e-12 45.4 0.0 1.2e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NTP_transferase PF00483.23 ORY48244.1 - 1.2e-30 107.0 0.0 1.6e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 ORY48244.1 - 1e-09 37.8 10.2 2.5e-06 27.0 0.6 3.9 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 ORY48244.1 - 1.5e-06 28.7 0.0 2.3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 ORY48244.1 - 0.0074 16.0 1.8 0.12 12.2 0.3 2.8 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Pkinase PF00069.25 ORY48245.1 - 2.2e-52 178.1 0.0 3e-30 105.5 0.0 3.6 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 ORY48245.1 - 1.3e-23 83.6 0.0 3.2e-14 52.9 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.7 ORY48245.1 - 4.9e-12 45.9 0.2 9.7e-12 44.9 0.2 1.4 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_His PF13393.6 ORY48245.1 - 1.2e-10 41.2 0.0 4e-05 23.0 0.0 2.6 1 1 1 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 ORY48245.1 - 4.7e-07 29.9 0.1 1.1e-06 28.7 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain RWD PF05773.22 ORY48245.1 - 3.8e-06 27.2 0.1 0.00011 22.4 0.1 2.8 1 1 0 1 1 1 1 RWD domain PMG PF05287.12 ORY48246.1 - 0.086 12.9 2.8 0.15 12.1 2.8 1.4 1 1 0 1 1 1 0 PMG protein Hydrolase_4 PF12146.8 ORY48247.1 - 2e-09 37.1 0.0 4.1e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY48247.1 - 4.1e-08 33.2 0.0 1e-07 31.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY48247.1 - 0.0002 22.0 0.0 0.00034 21.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 ORY48247.1 - 0.0087 16.0 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 Cutinase Palm_thioest PF02089.15 ORY48247.1 - 0.058 13.2 0.0 0.084 12.7 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Methyltransf_PK PF05891.12 ORY48249.1 - 1.9e-47 161.6 0.0 2.2e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 ORY48249.1 - 1.5e-07 32.0 0.0 2.2e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY48249.1 - 1.9e-06 28.5 0.0 2.9e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ORY48249.1 - 3.7e-05 23.1 0.0 4.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_11 PF08241.12 ORY48249.1 - 0.00014 22.5 0.0 0.00021 21.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY48249.1 - 0.019 14.8 0.0 0.16 11.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain B_lectin PF01453.24 ORY48250.1 - 0.0006 20.3 0.1 0.0053 17.3 0.0 1.9 1 1 1 2 2 2 1 D-mannose binding lectin SH3_15 PF18346.1 ORY48250.1 - 0.028 14.7 0.0 0.035 14.4 0.0 1.3 1 1 0 1 1 1 0 Mind bomb SH3 repeat domain SH3_1 PF00018.28 ORY48251.1 - 5.8e-39 131.5 1.0 1.5e-14 53.3 0.1 3.4 3 0 0 3 3 3 3 SH3 domain SH3_9 PF14604.6 ORY48251.1 - 2.2e-35 120.2 2.1 3.2e-14 52.5 0.1 3.5 3 0 0 3 3 3 3 Variant SH3 domain SH3_2 PF07653.17 ORY48251.1 - 7e-25 86.5 0.1 9.3e-09 34.8 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain FCH PF00611.23 ORY48251.1 - 1.8e-11 44.2 0.2 1.5e-10 41.2 0.2 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF2937 PF11157.8 ORY48251.1 - 0.05 13.3 2.8 7.4 6.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) SOAR PF16533.5 ORY48251.1 - 0.14 12.1 1.3 0.46 10.5 1.3 1.9 1 0 0 1 1 1 0 STIM1 Orai1-activating region RRM_1 PF00076.22 ORY48252.1 - 7e-23 80.2 0.4 2.4e-12 46.5 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_4 PF12799.7 ORY48252.1 - 1.5e-11 44.3 21.6 8.4e-06 26.1 2.5 4.5 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY48252.1 - 4.2e-07 29.6 26.5 0.0001 22.0 8.9 4.0 1 1 3 4 4 4 4 Leucine rich repeat RRM_occluded PF16842.5 ORY48252.1 - 0.00033 20.4 0.0 0.095 12.6 0.0 2.6 2 0 0 2 2 2 1 Occluded RNA-recognition motif LRR_1 PF00560.33 ORY48252.1 - 0.00038 20.6 21.9 1.2 9.9 1.4 6.3 6 0 0 6 6 5 3 Leucine Rich Repeat RRM_7 PF16367.5 ORY48252.1 - 0.0037 17.3 0.1 1.8 8.7 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif F-box PF00646.33 ORY48252.1 - 0.029 14.2 1.1 0.076 12.9 1.1 1.7 1 0 0 1 1 1 0 F-box domain RRM_Rrp7 PF17799.1 ORY48252.1 - 0.03 14.1 0.1 0.39 10.5 0.1 2.3 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain RRM_5 PF13893.6 ORY48252.1 - 0.033 13.8 0.0 0.26 10.9 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.7 ORY48252.1 - 0.049 13.5 0.7 0.13 12.2 0.7 1.7 1 0 0 1 1 1 0 F-box-like Di19_C PF14571.6 ORY48252.1 - 0.052 14.1 0.7 0.15 12.6 0.7 1.8 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal LRR_6 PF13516.6 ORY48252.1 - 0.37 11.0 15.2 42 4.6 0.1 5.7 5 0 0 5 5 5 0 Leucine Rich repeat PBP1_TM PF14812.6 ORY48252.1 - 0.38 11.2 3.8 0.89 10.0 3.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myosin_head PF00063.21 ORY48253.1 - 1.6e-287 955.3 1.0 1.6e-287 955.3 1.0 3.4 3 1 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 ORY48253.1 - 1.8e-93 314.2 324.3 7e-67 226.2 215.8 3.1 1 1 2 3 3 3 3 Myosin tail Myosin_N PF02736.19 ORY48253.1 - 1e-11 44.5 0.8 2.9e-11 43.0 0.8 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.27 ORY48253.1 - 0.0003 20.3 1.3 0.0003 20.3 1.3 2.7 2 0 0 2 2 2 1 IQ calmodulin-binding motif Erf4 PF10256.9 ORY48253.1 - 0.043 13.9 0.8 21 5.2 0.1 4.3 3 0 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family AAA_22 PF13401.6 ORY48253.1 - 0.43 10.8 0.0 0.43 10.8 0.0 5.9 6 1 1 7 7 7 0 AAA domain RINT1_TIP1 PF04437.13 ORY48254.1 - 5.6e-70 236.6 8.5 8.6e-70 236.0 8.5 1.2 1 0 0 1 1 1 1 RINT-1 / TIP-1 family ParD_antitoxin PF03693.14 ORY48254.1 - 0.037 14.4 0.6 0.94 9.9 0.0 3.1 3 0 0 3 3 3 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH Darcynin PF17074.5 ORY48254.1 - 0.077 13.2 0.3 0.42 10.9 0.1 2.2 2 0 0 2 2 2 0 Darcynin, domain of unknown function Ribosomal_L37ae PF01780.19 ORY48255.1 - 1.2e-40 137.5 12.4 1.3e-40 137.3 12.4 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 ORY48255.1 - 0.0048 16.9 3.0 0.0076 16.2 3.0 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-RING_13 PF17977.1 ORY48255.1 - 0.04 14.0 4.9 0.06 13.5 4.9 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1451 PF07295.11 ORY48255.1 - 0.12 12.4 0.9 0.17 11.9 0.9 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain A2L_zn_ribbon PF08792.10 ORY48255.1 - 0.38 10.5 4.6 9.8 6.0 1.3 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain MRNIP PF15749.5 ORY48255.1 - 0.44 11.3 4.6 12 6.6 1.0 2.3 1 1 1 2 2 2 0 MRN-interacting protein zf-BED PF02892.15 ORY48255.1 - 0.71 9.9 5.8 4.2 7.5 0.6 2.3 1 1 1 2 2 2 0 BED zinc finger DUF2013 PF09431.10 ORY48256.1 - 4.3e-34 117.6 4.4 9.3e-34 116.6 4.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) FAM92 PF06730.11 ORY48257.1 - 1.9e-15 56.9 8.3 2.5e-15 56.5 8.3 1.1 1 0 0 1 1 1 1 FAM92 protein I_LWEQ PF01608.17 ORY48257.1 - 0.0018 18.6 2.2 0.0023 18.2 0.2 2.0 1 1 1 2 2 2 1 I/LWEQ domain AbiJ_NTD5 PF18865.1 ORY48257.1 - 0.019 14.8 0.2 0.05 13.4 0.2 1.7 1 0 0 1 1 1 0 AbiJ N-terminal domain 5 DUF4897 PF16238.5 ORY48257.1 - 0.054 13.3 1.9 0.13 12.1 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4897) CENP-S PF15630.6 ORY48257.1 - 0.092 13.1 0.6 0.5 10.8 0.2 2.2 2 0 0 2 2 2 0 CENP-S protein BAR_3 PF16746.5 ORY48257.1 - 0.11 12.1 8.1 0.16 11.6 7.9 1.3 1 1 0 1 1 1 0 BAR domain of APPL family UQ_con PF00179.26 ORY48258.1 - 1.6e-47 160.7 0.0 1.7e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY48258.1 - 0.00035 20.3 0.0 0.00043 20.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 ORY48258.1 - 0.0065 16.3 0.1 0.013 15.4 0.1 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 ORY48258.1 - 0.044 14.1 0.1 0.055 13.8 0.1 1.3 1 1 0 1 1 1 0 RWD domain Glyco_transf_90 PF05686.12 ORY48259.1 - 8.6e-24 84.2 3.6 1.7e-23 83.2 3.6 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 ORY48259.1 - 0.0079 16.6 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 TruB_C_2 PF16198.5 ORY48260.1 - 0.019 15.1 0.0 0.03 14.5 0.0 1.3 1 0 0 1 1 1 0 tRNA pseudouridylate synthase B C-terminal domain FACT-Spt16_Nlob PF14826.6 ORY48261.1 - 3.5e-50 169.9 1.6 5e-49 166.2 0.2 2.5 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.11 ORY48261.1 - 2.2e-28 99.4 5.7 1e-16 61.5 0.0 3.1 2 1 1 3 3 3 2 FACT complex subunit (SPT16/CDC68) Rtt106 PF08512.12 ORY48261.1 - 5.3e-15 55.6 0.0 1.2e-14 54.4 0.0 1.7 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Peptidase_M24 PF00557.24 ORY48261.1 - 3.2e-07 30.3 0.0 2.8e-06 27.2 0.0 2.2 1 1 0 1 1 1 1 Metallopeptidase family M24 PPR_2 PF13041.6 ORY48262.1 - 1.4e-10 41.2 0.5 1e-06 28.8 0.0 3.4 3 1 1 4 4 4 2 PPR repeat family PPR_long PF17177.4 ORY48262.1 - 2.8e-07 30.1 0.0 0.00012 21.5 0.0 1.8 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 ORY48262.1 - 5.6e-07 29.4 1.1 0.019 15.2 0.0 3.6 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.6 ORY48262.1 - 0.0013 18.8 0.1 0.0065 16.5 0.0 2.1 2 1 1 3 3 3 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORY48262.1 - 0.043 13.5 0.4 6 6.7 0.1 3.3 3 0 0 3 3 3 0 PPR repeat RPM2 PF08579.11 ORY48262.1 - 0.051 14.0 0.0 0.18 12.2 0.0 1.8 1 1 1 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) PPR_2 PF13041.6 ORY48263.1 - 2.3e-10 40.5 0.0 6.4e-05 23.1 0.0 4.1 3 2 3 6 6 6 3 PPR repeat family PPR PF01535.20 ORY48263.1 - 2.6e-07 30.4 0.1 0.036 14.3 0.1 3.8 4 0 0 4 4 4 2 PPR repeat PPR_1 PF12854.7 ORY48263.1 - 0.0009 18.9 0.2 0.0054 16.4 0.0 2.5 3 0 0 3 3 3 1 PPR repeat PPR_3 PF13812.6 ORY48263.1 - 0.0014 18.6 0.0 1.1 9.4 0.0 3.3 3 1 1 4 4 4 2 Pentatricopeptide repeat domain TPR_14 PF13428.6 ORY48263.1 - 0.0091 16.7 0.0 1.1 10.3 0.1 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat PPR_long PF17177.4 ORY48263.1 - 0.18 11.2 0.0 1.7 8.0 0.0 2.2 2 1 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP OpuAC PF04069.12 ORY48264.1 - 0.0021 17.7 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system Neur_chan_memb PF02932.16 ORY48264.1 - 4 7.4 11.9 0.64 10.0 0.2 2.6 2 1 1 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Thioredoxin_16 PF18569.1 ORY48265.1 - 0.058 13.5 0.1 0.063 13.4 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain LRR_4 PF12799.7 ORY48266.1 - 6.9e-15 54.9 41.6 0.0082 16.5 0.0 10.1 6 2 6 12 12 12 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY48266.1 - 9e-07 28.6 26.0 0.014 15.2 3.0 7.3 6 1 1 7 7 7 4 Leucine rich repeat LRR_6 PF13516.6 ORY48266.1 - 4.3 7.6 19.1 24 5.3 0.1 7.0 7 0 0 7 7 7 0 Leucine Rich repeat OpuAC PF04069.12 ORY48267.1 - 4.2e-11 42.9 0.0 7.2e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Substrate binding domain of ABC-type glycine betaine transport system MatE PF01554.18 ORY48269.1 - 8.6e-64 214.0 21.1 9.1e-33 113.2 7.4 2.4 2 0 0 2 2 2 2 MatE Sel1 PF08238.12 ORY48270.1 - 3.1e-220 707.6 119.6 1.9e-11 44.3 0.5 22.7 23 0 0 23 23 22 21 Sel1 repeat Pkinase PF00069.25 ORY48270.1 - 1.9e-38 132.4 0.0 3.2e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY48270.1 - 1e-30 106.9 0.0 1.9e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DCX PF03607.17 ORY48270.1 - 6.4e-28 96.6 1.0 5.3e-13 48.9 0.1 3.6 3 0 0 3 3 3 3 Doublecortin LRR_8 PF13855.6 ORY48270.1 - 5.4e-13 48.5 29.4 3.5e-07 29.9 10.8 4.2 2 2 2 4 4 4 4 Leucine rich repeat TPR_16 PF13432.6 ORY48270.1 - 2.4e-12 47.3 70.4 0.08 13.6 1.2 14.4 4 3 12 17 17 17 10 Tetratricopeptide repeat LRR_4 PF12799.7 ORY48270.1 - 6.6e-12 45.4 33.7 0.00026 21.3 3.5 5.9 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) Flu_M1_C PF08289.11 ORY48270.1 - 6.5e-11 42.3 0.3 36 4.7 0.0 11.3 6 2 7 13 13 13 0 Influenza Matrix protein (M1) C-terminal domain DUF5112 PF17139.4 ORY48270.1 - 6.4e-06 25.8 37.0 0.68 9.4 0.1 11.1 4 2 10 15 15 15 3 Domain of unknown function (DUF5112) TPR_12 PF13424.6 ORY48270.1 - 0.00015 22.0 72.7 1.2 9.4 1.2 17.9 6 4 14 20 20 20 2 Tetratricopeptide repeat LRR_1 PF00560.33 ORY48270.1 - 0.003 17.9 36.1 0.14 12.8 0.8 8.5 8 0 0 8 8 8 2 Leucine Rich Repeat APH PF01636.23 ORY48270.1 - 0.058 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_6 PF13516.6 ORY48270.1 - 1 9.6 18.7 11 6.4 0.6 6.0 6 0 0 6 6 6 0 Leucine Rich repeat FNIP PF05725.12 ORY48270.1 - 1.9 8.7 4.7 15 5.8 2.6 3.5 1 1 1 2 2 2 0 FNIP Repeat pP_pnuc_1 PF18165.1 ORY48270.1 - 2.5 8.0 4.7 3.9e+02 0.9 0.1 5.4 4 2 4 8 8 8 0 Predicted pPIWI-associating nuclease PI3K_P85_iSH2 PF16454.5 ORY48271.1 - 0.0064 16.1 2.9 0.071 12.7 4.9 1.6 2 0 0 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Phage_GP20 PF06810.11 ORY48271.1 - 0.021 14.6 0.4 0.034 13.9 0.4 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 GTP-bdg_M PF16360.5 ORY48271.1 - 0.024 15.2 3.6 1.1 10.0 0.3 2.4 2 0 0 2 2 2 0 GTP-binding GTPase Middle Region MscS_porin PF12795.7 ORY48271.1 - 0.025 14.2 11.6 0.031 13.8 11.6 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF4763 PF15960.5 ORY48271.1 - 0.025 13.9 7.0 0.036 13.4 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Laminin_II PF06009.12 ORY48271.1 - 0.054 13.5 2.9 0.087 12.8 2.9 1.3 1 0 0 1 1 1 0 Laminin Domain II FlxA PF14282.6 ORY48271.1 - 0.055 13.5 9.2 0.086 12.8 9.2 1.3 1 0 0 1 1 1 0 FlxA-like protein DUF4200 PF13863.6 ORY48271.1 - 0.067 13.6 3.7 0.097 13.1 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) CENP-Q PF13094.6 ORY48271.1 - 0.082 13.1 3.1 0.11 12.7 3.1 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit FAM76 PF16046.5 ORY48271.1 - 0.097 12.0 6.2 0.14 11.5 6.2 1.2 1 0 0 1 1 1 0 FAM76 protein Baculo_p24 PF05073.12 ORY48271.1 - 0.11 12.3 2.5 0.15 11.8 2.5 1.2 1 0 0 1 1 1 0 Baculovirus P24 capsid protein DUF948 PF06103.11 ORY48271.1 - 0.13 12.5 7.6 2.4 8.5 3.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) PHD PF00628.29 ORY48272.1 - 7.3e-07 29.0 5.6 1.5e-06 28.0 5.6 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 ORY48272.1 - 0.052 13.1 4.5 1.1 8.8 0.4 2.4 2 0 0 2 2 2 0 PHD-finger Zf_RING PF16744.5 ORY48272.1 - 0.057 13.5 0.9 0.097 12.8 0.9 1.3 1 0 0 1 1 1 0 KIAA1045 RING finger FAM35_C PF15793.5 ORY48272.1 - 0.12 11.7 0.1 0.28 10.6 0.0 1.5 2 0 0 2 2 2 0 Protein family FAM35, C-terminal C1_1 PF00130.22 ORY48272.1 - 0.38 10.7 3.6 0.3 11.0 0.9 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FYRC PF05965.14 ORY48273.1 - 1.8e-05 24.8 0.0 3.2e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 F/Y rich C-terminus PAC2 PF09754.9 ORY48273.1 - 0.14 12.1 0.0 0.15 12.0 0.0 1.0 1 0 0 1 1 1 0 PAC2 family Pro_dh PF01619.18 ORY48275.1 - 3.7e-70 236.8 0.0 1.6e-69 234.7 0.0 1.8 1 1 0 1 1 1 1 Proline dehydrogenase AP_endonuc_2 PF01261.24 ORY48275.1 - 0.042 13.3 0.0 0.16 11.4 0.0 2.0 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Lipase_chap PF03280.14 ORY48275.1 - 0.16 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein Med17 PF10156.9 ORY48276.1 - 3e-13 49.3 0.0 1.2e-07 30.8 0.0 2.1 2 0 0 2 2 2 2 Subunit 17 of Mediator complex Cmc1 PF08583.10 ORY48277.1 - 2.2e-05 24.4 0.3 2.3e-05 24.3 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 ORY48277.1 - 0.00091 19.2 2.9 0.0015 18.5 0.5 2.2 2 1 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 ORY48277.1 - 0.0014 18.8 0.6 0.0034 17.6 0.6 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) CHCH PF06747.13 ORY48277.1 - 0.0036 17.4 4.7 0.0039 17.3 4.0 1.5 1 1 0 1 1 1 1 CHCH domain COX17 PF05051.13 ORY48277.1 - 0.036 14.4 0.7 0.15 12.4 0.8 1.8 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) DUF3128 PF11326.8 ORY48277.1 - 0.091 13.1 1.0 0.17 12.3 1.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) SMAP PF15477.6 ORY48278.1 - 1.6e-12 48.2 4.4 1.6e-12 48.2 4.4 4.0 2 1 0 2 2 2 1 Small acidic protein family TPR_MLP1_2 PF07926.12 ORY48279.1 - 0.016 15.3 15.4 0.016 15.3 15.4 3.9 2 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 ORY48279.1 - 0.13 12.5 47.0 0.044 14.0 2.6 6.0 1 1 3 5 5 5 0 TATA element modulatory factor 1 TATA binding LPP PF04728.13 ORY48279.1 - 0.17 12.3 8.0 14 6.2 0.1 4.9 4 1 1 5 5 5 0 Lipoprotein leucine-zipper DUF3138 PF11336.8 ORY48279.1 - 0.5 8.9 4.5 0.085 11.5 0.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF1664 PF07889.12 ORY48279.1 - 1.3 9.1 0.0 1.3 9.1 0.0 4.5 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) NSP2-B_epitope PF14757.6 ORY48279.1 - 1.4 8.5 3.4 0.55 9.9 0.8 1.5 2 0 0 2 2 2 0 Immunogenic region of nsp2 protein of arterivirus polyprotein DUF4579 PF15158.6 ORY48280.1 - 2.2e-37 128.6 1.6 2.6e-37 128.4 1.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4579) DUF4870 PF09685.10 ORY48280.1 - 0.1 12.7 4.3 0.16 12.1 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) CAP18_C PF12153.8 ORY48280.1 - 0.12 12.2 0.4 0.21 11.5 0.4 1.3 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) DUF2207 PF09972.9 ORY48280.1 - 8 5.1 7.8 5.3 5.7 6.5 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Glyco_transf_34 PF05637.12 ORY48281.1 - 9.6e-05 22.2 0.9 0.0041 16.9 0.5 2.1 2 0 0 2 2 2 2 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 ORY48281.1 - 0.002 18.2 0.0 0.0027 17.7 0.0 1.4 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase zf-RING_13 PF17977.1 ORY48283.1 - 0.17 12.0 0.0 0.32 11.1 0.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain WD40 PF00400.32 ORY48284.1 - 9.5e-24 83.2 14.0 3.1e-06 27.8 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY48284.1 - 4.8e-06 26.8 0.1 0.038 14.3 0.0 4.7 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 ORY48284.1 - 0.00016 21.3 3.5 0.0021 17.7 1.7 3.1 1 1 1 2 2 2 1 PQQ-like domain Nup160 PF11715.8 ORY48284.1 - 0.0006 18.6 0.2 0.22 10.1 0.1 2.8 2 1 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 ORY48284.1 - 0.026 15.0 3.1 45 4.7 0.1 5.1 6 1 1 7 7 7 0 PQQ-like domain BBS2_Mid PF14783.6 ORY48284.1 - 0.058 13.4 0.0 0.39 10.8 0.0 2.4 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PMI_typeI PF01238.21 ORY48285.1 - 5.8e-112 374.6 0.0 7.9e-112 374.1 0.0 1.2 1 0 0 1 1 1 1 Phosphomannose isomerase type I DUF2407_C PF13373.6 ORY48285.1 - 2.8e-11 43.8 0.1 5e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.9 ORY48285.1 - 3e-07 31.0 0.0 7.4e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 ORY48285.1 - 7.9e-07 28.7 0.0 1.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 ORY48285.1 - 5.7e-05 23.2 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Cupin_2 PF07883.11 ORY48285.1 - 0.0018 17.9 0.7 0.17 11.6 0.7 2.3 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.19 ORY48285.1 - 0.036 14.0 0.0 9.2 6.2 0.1 2.5 2 0 0 2 2 2 0 AraC-like ligand binding domain Sec10 PF07393.11 ORY48286.1 - 6.6e-170 567.0 0.1 3e-169 564.8 0.1 1.8 1 1 0 1 1 1 1 Exocyst complex component Sec10 MscS_porin PF12795.7 ORY48286.1 - 0.011 15.3 0.7 0.019 14.5 0.7 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain CREPT PF16566.5 ORY48286.1 - 0.054 13.7 0.2 0.17 12.1 0.2 1.8 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour Vps53_N PF04100.12 ORY48286.1 - 0.098 11.6 1.1 0.32 9.9 1.1 1.8 1 0 0 1 1 1 0 Vps53-like, N-terminal ApoLp-III PF07464.11 ORY48286.1 - 0.1 12.7 0.9 3.3 7.8 0.0 3.2 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Serine_rich PF08824.10 ORY48286.1 - 0.1 12.6 0.4 0.28 11.2 0.4 1.8 1 0 0 1 1 1 0 Serine rich protein interaction domain MnmE_helical PF12631.7 ORY48286.1 - 0.1 12.7 3.0 0.26 11.4 3.0 1.7 1 1 0 1 1 1 0 MnmE helical domain Gly_rich PF12810.7 ORY48288.1 - 0.005 16.8 1.6 0.005 16.8 1.6 2.3 2 0 0 2 2 2 1 Glycine rich protein IQCJ-SCHIP1 PF15157.6 ORY48288.1 - 0.017 14.9 0.2 0.047 13.5 0.2 1.7 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif PIN_2 PF10130.9 ORY48288.1 - 0.12 12.6 2.7 0.45 10.7 2.7 2.0 1 0 0 1 1 1 0 PIN domain Ribosomal_L2 PF00181.23 ORY48288.1 - 0.61 10.1 2.9 0.94 9.5 0.1 2.6 2 0 0 2 2 2 0 Ribosomal Proteins L2, RNA binding domain Dpy-30 PF05186.13 ORY48290.1 - 1.6e-19 69.3 0.3 3.1e-19 68.4 0.0 1.7 2 0 0 2 2 2 1 Dpy-30 motif ADK PF00406.22 ORY48290.1 - 1.5e-11 44.6 2.5 2.1e-10 40.9 0.2 2.8 2 1 0 2 2 2 1 Adenylate kinase Hydin_ADK PF17213.3 ORY48290.1 - 4.3e-10 40.2 1.3 1.2e-06 29.0 0.0 2.9 3 0 0 3 3 3 2 Hydin Adenylate kinase-like domain AAA_17 PF13207.6 ORY48290.1 - 1.4e-09 38.5 3.8 6.5e-05 23.4 0.0 3.2 2 1 1 3 3 3 2 AAA domain AAA PF00004.29 ORY48290.1 - 0.0001 22.7 2.1 0.0016 18.9 0.0 2.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 ORY48290.1 - 0.00082 19.6 0.0 0.0022 18.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 ORY48290.1 - 0.0029 17.9 0.3 0.013 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY48290.1 - 0.0068 17.0 0.2 0.099 13.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 ORY48290.1 - 0.023 14.7 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ORY48290.1 - 0.039 14.3 0.1 0.11 12.9 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 ORY48290.1 - 0.11 12.7 0.0 0.43 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 ORY48290.1 - 0.14 11.9 1.0 13 5.4 2.1 2.3 2 0 0 2 2 2 0 AAA domain tRNA-synt_1c PF00749.21 ORY48290.1 - 3 6.6 8.6 0.73 8.7 4.7 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain zf-ribbon_3 PF13248.6 ORY48291.1 - 0.12 11.8 1.2 0.28 10.6 1.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain EMP70 PF02990.16 ORY48292.1 - 1.8e-29 102.8 0.0 2e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 EMP70 PF02990.16 ORY48293.1 - 5.9e-81 272.7 27.5 1.9e-76 257.9 18.1 2.3 2 1 1 3 3 3 2 Endomembrane protein 70 OAD_gamma PF04277.13 ORY48293.1 - 2.5 8.7 0.0 2.5 8.7 0.0 3.0 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain MFS_1 PF07690.16 ORY48294.1 - 1.1e-17 64.1 12.6 1.3e-17 63.8 12.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.16 ORY48295.1 - 6.6e-07 28.6 9.5 7.9e-07 28.3 8.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 ORY48295.1 - 0.21 10.4 4.5 0.12 11.2 0.7 1.9 2 0 0 2 2 2 0 MFS_1 like family Proteasome PF00227.26 ORY48296.1 - 4.9e-55 186.0 0.2 7.8e-55 185.3 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORY48296.1 - 4e-15 55.2 0.1 8.1e-15 54.2 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ank_2 PF12796.7 ORY48297.1 - 5.1e-14 52.6 0.0 0.0027 18.3 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY48297.1 - 1e-06 28.9 1.6 1.9 8.9 0.0 5.5 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY48297.1 - 0.003 18.1 0.2 0.66 10.6 0.1 3.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY48297.1 - 0.0035 17.7 0.6 9.8 7.1 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat PAC1 PF16094.5 ORY48298.1 - 0.011 15.0 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 DUF962 PF06127.11 ORY48300.1 - 2e-20 72.7 0.1 3.5e-20 71.9 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Bestrophin PF01062.21 ORY48301.1 - 1e-33 117.0 1.2 1.7e-33 116.3 1.2 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel TauD PF02668.16 ORY48302.1 - 1.5e-51 175.7 1.0 2e-51 175.3 1.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Nuc_sug_transp PF04142.15 ORY48303.1 - 2e-116 388.6 18.9 2.5e-116 388.2 18.9 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 ORY48303.1 - 4.6e-06 26.0 16.1 1.1e-05 24.8 16.0 1.6 1 1 0 1 1 1 1 UAA transporter family PUNUT PF16913.5 ORY48303.1 - 6.7e-05 22.3 20.2 0.00014 21.2 20.2 1.6 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport EamA PF00892.20 ORY48303.1 - 0.00025 21.2 3.9 0.00025 21.2 3.9 2.5 2 1 0 2 2 2 1 EamA-like transporter family CRT-like PF08627.10 ORY48303.1 - 0.38 9.6 14.8 0.0082 15.1 6.6 1.9 1 1 1 2 2 2 0 CRT-like, chloroquine-resistance transporter-like TPT PF03151.16 ORY48303.1 - 0.54 9.6 18.9 0.023 14.1 5.4 2.4 1 1 1 2 2 2 0 Triose-phosphate Transporter family Nuc_sug_transp PF04142.15 ORY48304.1 - 6.1e-116 387.0 19.3 7.5e-116 386.7 19.3 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 ORY48304.1 - 8.5e-09 35.0 15.9 1.9e-08 33.9 15.9 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 ORY48304.1 - 7.1e-07 29.5 25.2 1.6e-06 28.3 2.9 2.6 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 ORY48304.1 - 8.3e-06 25.4 23.2 0.00021 20.7 4.4 2.6 1 1 1 2 2 2 2 Triose-phosphate Transporter family PUNUT PF16913.5 ORY48304.1 - 0.0024 17.2 20.3 0.0072 15.6 20.3 1.8 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport DUF202 PF02656.15 ORY48304.1 - 0.033 14.6 0.9 0.033 14.6 0.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Ceramidase PF05875.12 ORY48304.1 - 2.5 7.5 10.8 0.049 13.0 3.7 1.8 2 1 0 2 2 2 0 Ceramidase Peptidase_M1 PF01433.20 ORY48305.1 - 2.3e-83 279.1 0.3 3.8e-83 278.3 0.3 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 ORY48305.1 - 5.6e-61 206.8 0.8 5.6e-61 206.8 0.8 1.6 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 ORY48305.1 - 4e-50 170.6 0.9 5.3e-49 166.9 0.3 2.3 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 ORY48305.1 - 0.078 12.9 0.0 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2808) DUF3458 PF11940.8 ORY48305.1 - 0.11 12.9 0.0 0.34 11.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3458) Ig-like fold HEAT_2 PF13646.6 ORY48305.1 - 0.16 12.4 0.2 12 6.4 0.0 3.1 2 1 0 2 2 2 0 HEAT repeats Aminotran_5 PF00266.19 ORY48306.1 - 1.3e-14 53.9 0.0 3.6e-14 52.5 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ORY48306.1 - 8.3e-05 21.3 0.0 0.00018 20.2 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ORY48306.1 - 0.0016 17.7 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II C2 PF00168.30 ORY48307.1 - 4.9e-11 42.8 0.0 1.5e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.9 ORY48307.1 - 4.3e-06 27.0 1.4 8.8e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain DUF810 PF05664.11 ORY48307.1 - 0.1 11.1 0.4 0.37 9.3 0.0 2.0 3 0 0 3 3 3 0 Plant family of unknown function (DUF810) DUF2835 PF11197.8 ORY48307.1 - 0.17 11.7 0.1 0.47 10.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2835) Nuc_sug_transp PF04142.15 ORY48308.1 - 3.7e-116 387.7 21.5 4.7e-116 387.4 21.5 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 ORY48308.1 - 2.1e-05 24.7 5.1 2.1e-05 24.7 5.1 3.0 2 1 1 3 3 3 1 EamA-like transporter family PUNUT PF16913.5 ORY48308.1 - 3e-05 23.4 19.6 8.9e-05 21.9 19.6 1.8 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport TPT PF03151.16 ORY48308.1 - 0.0036 16.7 6.1 0.0036 16.7 6.1 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EMP70 PF02990.16 ORY48309.1 - 3e-195 649.8 15.1 4e-195 649.4 15.1 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 OpuAC PF04069.12 ORY48310.1 - 1.3e-08 34.8 0.3 6.5e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 Substrate binding domain of ABC-type glycine betaine transport system Ephrin_rec_like PF07699.13 ORY48310.1 - 0.0024 17.6 4.5 0.0024 17.6 4.5 3.7 4 1 0 4 4 4 1 Putative ephrin-receptor like LuxS PF02664.15 ORY48310.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 S-Ribosylhomocysteinase (LuxS) SMC_N PF02463.19 ORY48311.1 - 1.1e-61 208.0 14.5 2.6e-61 206.9 14.5 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 ORY48311.1 - 1.4e-28 99.5 0.0 6.6e-28 97.4 0.0 2.3 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 ORY48311.1 - 9.5e-11 42.0 10.7 7.1e-07 29.3 0.1 3.7 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY48311.1 - 3.4e-08 33.1 0.0 7.9e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 ORY48311.1 - 2.2e-07 31.0 20.4 2.2e-07 31.0 20.4 4.8 2 2 2 4 4 4 1 AAA ATPase domain AAA_23 PF13476.6 ORY48311.1 - 9.5e-07 29.5 36.0 9.5e-07 29.5 36.0 6.9 3 2 1 4 4 4 1 AAA domain ABC_tran_CTD PF16326.5 ORY48311.1 - 0.00038 20.7 7.9 0.00038 20.7 7.9 9.4 5 4 3 9 9 9 1 ABC transporter C-terminal domain SbcCD_C PF13558.6 ORY48311.1 - 0.0029 17.8 0.0 0.018 15.3 0.0 2.4 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 ORY48311.1 - 0.15 12.3 4.7 39 4.5 0.0 4.5 4 0 0 4 4 4 0 AAA domain Cyto_heme_lyase PF01265.17 ORY48313.1 - 9.5e-57 192.8 7.0 1.5e-55 188.9 7.0 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Ribosomal_L30 PF00327.20 ORY48314.1 - 3.7e-10 39.5 0.1 6.7e-10 38.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Pectate_lyase22 PF14583.6 ORY48314.1 - 0.26 9.9 0.1 0.32 9.6 0.1 1.1 1 0 0 1 1 1 0 Oligogalacturonate lyase IU_nuc_hydro PF01156.19 ORY48315.1 - 4.1e-36 125.1 0.0 5.7e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DSBA PF01323.20 ORY48316.1 - 7.6e-29 100.9 0.0 8.7e-29 100.7 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 ORY48316.1 - 0.0004 20.6 0.0 0.014 15.5 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 ORY48316.1 - 0.00067 19.7 0.2 0.092 12.8 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin domain Ank_2 PF12796.7 ORY48317.1 - 6.9e-15 55.4 0.5 0.0002 21.9 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY48317.1 - 1.8e-06 28.1 4.9 0.15 12.4 0.1 5.4 4 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY48317.1 - 6.8e-05 23.3 5.2 0.2 12.3 0.1 4.6 5 2 0 5 5 5 2 Ankyrin repeats (many copies) F-box-like PF12937.7 ORY48317.1 - 0.032 14.1 0.1 0.062 13.2 0.1 1.5 1 0 0 1 1 1 0 F-box-like Ank_3 PF13606.6 ORY48317.1 - 0.061 13.9 9.2 9.9 7.1 0.0 6.1 6 0 0 6 6 6 0 Ankyrin repeat E1-E2_ATPase PF00122.20 ORY48318.1 - 7.7e-43 146.1 3.9 7.7e-43 146.1 3.9 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY48318.1 - 9.6e-40 136.2 7.8 9.6e-40 136.2 7.8 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY48318.1 - 1.8e-16 61.1 1.5 2e-07 31.5 0.4 3.1 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY48318.1 - 3.1e-15 56.0 0.0 7.5e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY48318.1 - 1.3e-05 25.1 0.9 4.3e-05 23.4 0.9 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 ORY48318.1 - 0.0032 17.1 0.0 0.0081 15.8 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.7 ORY48318.1 - 0.14 12.5 0.0 4.8 7.5 0.0 2.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Colicin_V PF02674.16 ORY48318.1 - 2.7 8.0 14.9 2.9 7.9 2.2 3.5 3 1 0 3 3 3 0 Colicin V production protein RNase_PH PF01138.21 ORY48320.1 - 3.8e-24 85.7 0.1 7.2e-24 84.8 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ORY48320.1 - 2.9e-06 27.2 0.0 4.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 MTS PF05175.14 ORY48321.1 - 5.1e-10 39.2 0.0 8.5e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 ORY48321.1 - 2.6e-07 30.6 0.0 4.2e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY48321.1 - 6.1e-06 26.9 0.0 1.5e-05 25.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY48321.1 - 0.00012 22.8 0.0 0.00032 21.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 ORY48321.1 - 0.00013 21.5 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 ORY48321.1 - 0.0014 18.3 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 ORY48321.1 - 0.0015 18.5 0.0 0.0035 17.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain N6_Mtase PF02384.16 ORY48321.1 - 0.0033 16.7 0.0 0.0083 15.4 0.0 1.6 1 1 1 2 2 2 1 N-6 DNA Methylase Ubie_methyltran PF01209.18 ORY48321.1 - 0.0036 16.7 0.0 0.009 15.4 0.0 1.7 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family PrmC_N PF17827.1 ORY48321.1 - 0.0076 16.8 0.0 0.023 15.3 0.0 1.8 2 0 0 2 2 2 1 PrmC N-terminal domain Methyltransf_11 PF08241.12 ORY48321.1 - 0.02 15.5 0.0 0.038 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_10 PF05971.12 ORY48321.1 - 0.037 13.4 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 RNA methyltransferase Glutaredoxin PF00462.24 ORY48322.1 - 1.1e-21 76.8 0.0 1.4e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 ORY48322.1 - 0.00027 21.3 0.0 0.00034 21.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_2 PF13098.6 ORY48322.1 - 0.00031 21.2 0.1 0.00049 20.5 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 ORY48322.1 - 0.0011 19.4 0.0 0.0012 19.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_3 PF13192.6 ORY48322.1 - 0.0038 17.2 0.0 0.0051 16.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_4 PF13462.6 ORY48322.1 - 0.026 14.7 0.3 0.18 11.9 0.2 1.9 1 1 0 2 2 2 0 Thioredoxin DSBA PF01323.20 ORY48322.1 - 0.057 13.2 0.1 0.59 9.9 0.1 1.9 1 1 0 2 2 2 0 DSBA-like thioredoxin domain TraF PF13728.6 ORY48322.1 - 0.062 13.1 0.0 0.066 13.0 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein GST_N_2 PF13409.6 ORY48322.1 - 0.065 13.6 0.0 0.078 13.3 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_9 PF14595.6 ORY48322.1 - 0.14 11.9 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Ponericin PF07442.11 ORY48323.1 - 0.18 11.9 0.3 0.3 11.1 0.3 1.3 1 0 0 1 1 1 0 Ponericin DUF3934 PF13070.6 ORY48324.1 - 2.1 8.9 6.2 4.8 7.7 6.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3934) E1-E2_ATPase PF00122.20 ORY48325.1 - 2.8e-44 150.8 3.1 2.8e-44 150.8 3.1 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY48325.1 - 3.5e-39 134.4 7.3 3.5e-39 134.4 7.3 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY48325.1 - 9.5e-17 62.0 0.4 2.5e-07 31.2 0.2 3.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY48325.1 - 1.7e-15 56.9 0.0 4.1e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORY48325.1 - 7.4e-07 28.8 0.0 1.5e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY48325.1 - 6.2e-06 26.1 0.6 1.5e-05 24.9 0.6 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY48325.1 - 0.052 13.9 0.1 6.2 7.2 0.0 2.4 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF1751 PF08551.10 ORY48325.1 - 0.48 11.0 4.6 0.36 11.4 1.4 2.5 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Gelsolin PF00626.22 ORY48326.1 - 1.1e-42 143.8 0.0 5.7e-15 55.0 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat Tail_spike_N PF18668.1 ORY48326.1 - 0.087 12.7 0.0 20 5.1 0.0 2.6 2 0 0 2 2 2 0 Tail spike TSP1/Gp66 receptor binding N-terminal domain Ank_2 PF12796.7 ORY48327.1 - 3.9e-10 40.2 0.0 4.4e-05 24.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) F-box-like PF12937.7 ORY48327.1 - 0.016 15.1 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 ORY48327.1 - 0.033 14.1 0.1 0.072 13.0 0.1 1.6 1 0 0 1 1 1 0 F-box domain PRANC PF09372.10 ORY48327.1 - 0.081 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 PRANC domain DEAD PF00270.29 ORY48329.1 - 3.7e-37 127.8 0.2 3e-36 124.8 0.2 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY48329.1 - 2.8e-21 76.0 0.0 2.5e-20 72.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY48329.1 - 9.3e-11 42.0 0.0 1.7e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 ORY48329.1 - 0.0034 17.7 1.5 0.019 15.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 ORY48329.1 - 0.028 14.7 0.0 0.06 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 ORY48329.1 - 0.088 12.2 0.5 0.19 11.2 0.1 1.7 2 0 0 2 2 2 0 PhoH-like protein HHH_2 PF12826.7 ORY48330.1 - 4.5e-10 39.5 0.1 8.7e-10 38.6 0.1 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 ORY48330.1 - 4.6e-06 27.1 0.5 9.1e-06 26.2 0.5 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain 5_3_exonuc PF01367.20 ORY48330.1 - 0.00023 21.7 0.2 0.0019 18.7 0.2 2.2 1 1 1 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold PND PF17949.1 ORY48330.1 - 0.00066 19.9 0.1 0.0011 19.2 0.1 1.3 1 0 0 1 1 1 1 FANCM pseudonuclease domain DUF3701 PF12482.8 ORY48330.1 - 0.018 15.1 0.1 0.88 9.7 0.0 2.3 1 1 1 2 2 2 0 Phage integrase protein HHH_3 PF12836.7 ORY48330.1 - 0.028 14.7 0.1 0.62 10.4 0.0 2.4 1 1 1 2 2 2 0 Helix-hairpin-helix motif HHH PF00633.23 ORY48330.1 - 0.17 11.8 1.1 2.3 8.2 0.4 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif Ank_2 PF12796.7 ORY48331.1 - 8.9e-07 29.4 0.1 1.6e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY48331.1 - 2.2e-06 27.8 0.1 8.3e-06 26.0 0.1 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 ORY48331.1 - 1.9e-05 25.1 0.4 0.008 16.7 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY48331.1 - 0.00017 21.8 0.0 0.00069 19.9 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) MMR_HSR1 PF01926.23 ORY48332.1 - 3.5e-09 36.7 0.2 6.3e-09 35.9 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY48332.1 - 2.9e-06 27.3 0.3 1.1e-05 25.4 0.3 1.9 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 ORY48332.1 - 9.4e-05 22.0 0.1 0.00016 21.2 0.1 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 ORY48332.1 - 9.5e-05 21.8 0.4 0.00015 21.2 0.4 1.2 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 ORY48332.1 - 0.00013 22.5 0.4 0.00019 21.9 0.4 1.6 1 1 0 1 1 1 1 ABC transporter Septin PF00735.18 ORY48332.1 - 0.0005 19.4 0.1 0.00088 18.6 0.1 1.4 1 0 0 1 1 1 1 Septin AAA_30 PF13604.6 ORY48332.1 - 0.00067 19.4 0.2 0.0011 18.8 0.2 1.3 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 ORY48332.1 - 0.0049 16.8 0.1 0.0099 15.8 0.1 1.6 1 0 0 1 1 1 1 NTPase AAA_16 PF13191.6 ORY48332.1 - 0.0075 16.7 0.0 0.013 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 ORY48332.1 - 0.0077 16.0 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 ORY48332.1 - 0.011 15.7 0.0 0.43 10.5 0.0 2.4 2 1 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 ORY48332.1 - 0.011 16.0 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 ORY48332.1 - 0.019 14.9 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Viral_helicase1 PF01443.18 ORY48332.1 - 0.029 14.1 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ADK PF00406.22 ORY48332.1 - 0.041 14.0 0.0 0.39 10.8 0.1 2.2 2 0 0 2 2 2 0 Adenylate kinase cobW PF02492.19 ORY48332.1 - 0.057 13.0 0.1 0.18 11.4 0.0 1.8 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 ORY48332.1 - 0.076 13.2 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 ORY48332.1 - 0.088 13.2 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 ORY48332.1 - 0.11 12.3 0.1 0.62 9.8 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Fascin PF06268.13 ORY48332.1 - 0.12 12.5 0.1 0.51 10.6 0.0 1.9 1 1 1 2 2 2 0 Fascin domain Ank PF00023.30 ORY48333.1 - 0.015 15.7 0.7 1.1 9.9 0.6 3.5 3 1 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 ORY48333.1 - 0.016 15.5 0.0 2.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY48333.1 - 0.1 13.2 0.0 0.35 11.5 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeats (many copies) CPSF100_C PF13299.6 ORY48333.1 - 0.68 10.1 3.0 11 6.1 0.1 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Cgr1 PF03879.14 ORY48334.1 - 1.4e-17 64.1 32.4 1.8e-17 63.7 32.4 1.1 1 0 0 1 1 1 1 Cgr1 family RPA43_OB PF17875.1 ORY48334.1 - 0.1 13.2 7.3 0.14 12.7 7.3 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I LicD PF04991.13 ORY48334.1 - 0.75 9.9 6.8 0.94 9.6 6.8 1.1 1 0 0 1 1 1 0 LicD family PBP_sp32 PF07222.12 ORY48334.1 - 0.94 8.9 8.6 1.1 8.6 8.6 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 D5_N PF08706.11 ORY48334.1 - 2.3 8.4 9.7 3.1 8.1 9.7 1.2 1 0 0 1 1 1 0 D5 N terminal like Lipoprotein_8 PF02030.15 ORY48334.1 - 4.1 6.0 9.0 4.9 5.8 9.0 1.0 1 0 0 1 1 1 0 Hypothetical lipoprotein (MG045 family) DDHD PF02862.17 ORY48334.1 - 4.2 7.5 7.8 4.9 7.2 7.8 1.1 1 0 0 1 1 1 0 DDHD domain DUF2058 PF09831.9 ORY48334.1 - 9 6.4 22.2 3.1 7.9 19.8 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Glyco_hydro_1 PF00232.18 ORY48335.1 - 1.3e-91 307.3 8.1 9.5e-91 304.5 7.3 2.3 2 1 0 2 2 2 1 Glycosyl hydrolase family 1 Spermine_synth PF01564.17 ORY48335.1 - 4.3e-06 26.3 0.0 7.8e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_25 PF13649.6 ORY48335.1 - 2.7e-05 24.8 0.0 7.2e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ORY48335.1 - 9.8e-05 21.7 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 ORY48335.1 - 0.003 17.1 0.0 0.0071 15.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 ORY48335.1 - 0.026 15.3 0.0 0.048 14.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 ORY48335.1 - 0.087 13.5 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_1 PF00232.18 ORY48336.1 - 4e-95 318.9 8.2 2.9e-94 316.1 8.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Aldedh PF00171.22 ORY48337.1 - 1.8e-81 274.0 0.0 2.4e-81 273.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OrfB_IS605 PF01385.19 ORY48338.1 - 0.59 10.4 3.1 0.97 9.7 0.1 2.7 3 0 0 3 3 3 0 Probable transposase NARP1 PF12569.8 ORY48339.1 - 1.1e-175 585.4 27.3 8.3e-174 579.3 18.9 2.0 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_14 PF13428.6 ORY48339.1 - 6.3e-18 63.9 12.4 0.03 15.1 0.1 10.5 9 2 2 11 11 10 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY48339.1 - 1.1e-17 62.6 35.5 1.1e-05 25.1 0.2 10.0 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 ORY48339.1 - 2.8e-16 59.8 14.8 0.0035 17.8 0.2 8.2 7 1 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 ORY48339.1 - 2e-15 55.6 24.0 0.00016 21.6 0.2 9.4 11 0 0 11 11 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 ORY48339.1 - 4.8e-12 45.4 8.3 0.01 16.2 0.0 8.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 ORY48339.1 - 3.1e-11 43.7 6.5 0.7 10.6 0.0 7.8 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY48339.1 - 8.5e-11 41.2 26.5 5.5e-05 22.8 0.5 8.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY48339.1 - 2e-08 33.8 4.3 0.0017 18.0 0.1 5.3 5 0 0 5 5 5 2 TPR repeat TPR_12 PF13424.6 ORY48339.1 - 8.4e-08 32.4 13.7 0.04 14.2 0.5 7.2 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY48339.1 - 1.3e-07 31.6 2.0 0.78 9.9 0.1 6.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY48339.1 - 1.4e-07 31.0 8.8 0.007 16.3 0.1 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY48339.1 - 2e-06 27.9 17.0 0.019 15.2 0.7 5.6 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.14 ORY48339.1 - 5.1e-06 26.6 5.2 9.4 7.2 0.1 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_15 PF13429.6 ORY48339.1 - 1.9e-05 24.0 6.1 0.36 10.0 0.1 4.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY48339.1 - 0.00056 20.4 17.5 42 5.1 0.1 8.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY48339.1 - 0.0095 15.3 3.3 0.75 9.1 0.1 3.1 3 1 1 4 4 4 1 MalT-like TPR region TPR_3 PF07720.12 ORY48339.1 - 1.2 9.2 4.5 24 5.0 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3042 PF11240.8 ORY48339.1 - 2.5 8.2 4.6 1.4 9.0 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) TPR_10 PF13374.6 ORY48339.1 - 3.8 7.5 16.0 1.1 9.2 0.1 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Pkinase PF00069.25 ORY48340.1 - 1.1e-07 31.5 0.1 2.9e-07 30.1 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 ORY48340.1 - 8.3e-06 25.9 0.2 7.9e-05 22.7 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY48340.1 - 0.00086 18.7 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORY48340.1 - 0.00093 18.8 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 ORY48340.1 - 0.0055 16.0 0.2 0.019 14.2 0.2 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 ORY48340.1 - 0.0065 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 ORY48340.1 - 0.016 14.2 0.0 0.037 13.0 0.0 1.6 1 0 0 1 1 1 0 Haspin like kinase domain Amidase02_C PF12123.8 ORY48341.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF5070 PF16802.5 ORY48341.1 - 0.16 12.0 0.1 0.28 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5070) Acyl_transf_3 PF01757.22 ORY48341.1 - 1.8 7.5 8.9 4.9 6.1 8.9 1.8 1 1 0 1 1 1 0 Acyltransferase family TIR_2 PF13676.6 ORY48342.1 - 9.5e-06 26.2 0.0 2.5e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 TIR domain DWNN PF08783.11 ORY48342.1 - 0.26 11.6 1.5 1.3 9.4 0.2 2.6 2 0 0 2 2 2 0 DWNN domain DUF1796 PF08795.10 ORY48343.1 - 0.14 12.1 0.3 0.43 10.5 0.3 1.8 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) WD40 PF00400.32 ORY48427.1 - 7e-61 200.8 29.9 1.1e-10 41.8 0.2 6.6 7 0 0 7 7 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY48427.1 - 1.6e-27 95.6 2.5 3.5e-05 24.0 0.1 6.3 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY48427.1 - 1.2e-11 43.9 7.9 0.32 9.6 0.1 6.1 1 1 5 7 7 7 5 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY48427.1 - 5e-09 35.9 0.0 0.0072 15.7 0.0 3.5 1 1 3 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 ORY48427.1 - 3.3e-08 32.9 13.3 0.059 12.3 0.2 6.7 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF5122 PF17164.4 ORY48427.1 - 5.4e-05 23.4 8.6 17 5.8 0.2 5.5 5 0 0 5 5 5 0 Domain of unknown function (DUF5122) beta-propeller PD40 PF07676.12 ORY48427.1 - 0.00011 22.0 0.0 20 5.3 0.0 5.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Prot_ATP_ID_OB PF16450.5 ORY48427.1 - 0.00033 20.5 4.7 7.6 6.6 0.0 5.1 6 0 0 6 6 6 2 Proteasomal ATPase OB C-terminal domain DUF4875 PF16175.5 ORY48427.1 - 0.021 14.9 14.4 0.3 11.2 0.3 4.5 1 1 4 5 5 5 0 Domain of unknown function (DUF4875) Hint PF01079.20 ORY48427.1 - 0.041 13.4 2.2 13 5.2 0.1 3.7 2 2 3 5 5 5 0 Hint module Colicin_Ia PF11504.8 ORY48427.1 - 0.13 12.4 1.3 1.2e+02 2.9 0.0 4.5 5 0 0 5 5 5 0 Colicin Ia 120_Rick_ant PF12574.8 ORY48427.1 - 1.7 7.8 3.5 9 5.4 0.1 2.8 2 1 1 3 3 3 0 120 KDa Rickettsia surface antigen TIR_2 PF13676.6 ORY48428.1 - 4.6e-08 33.7 0.0 9.1e-08 32.7 0.0 1.5 1 1 0 1 1 1 1 TIR domain TIR PF01582.20 ORY48428.1 - 0.00013 21.8 0.0 0.00017 21.4 0.0 1.1 1 0 0 1 1 1 1 TIR domain AAA_30 PF13604.6 ORY48428.1 - 0.011 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Nuc_deoxyrib_tr PF05014.15 ORY48428.1 - 0.013 15.5 0.0 0.016 15.2 0.0 1.2 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase AAA_19 PF13245.6 ORY48428.1 - 0.09 13.1 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY48428.1 - 0.096 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region PIF1 PF05970.14 ORY48428.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase AFG1_ATPase PF03969.16 ORY48428.1 - 0.24 10.2 0.0 0.34 9.7 0.0 1.2 1 0 0 1 1 1 0 AFG1-like ATPase DUF2075 PF09848.9 ORY48428.1 - 0.26 10.5 0.0 0.37 10.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF3712 PF12505.8 ORY48429.1 - 8.4e-50 168.2 34.3 3.5e-23 82.2 0.9 5.7 6 0 0 6 6 6 4 Protein of unknown function (DUF3712) zf-B_box PF00643.24 ORY48430.1 - 0.0039 17.3 9.2 0.0039 17.3 9.2 2.2 2 0 0 2 2 2 1 B-box zinc finger Zn_Tnp_IS91 PF14319.6 ORY48430.1 - 0.033 14.2 3.9 0.033 14.2 3.9 1.9 2 0 0 2 2 2 0 Transposase zinc-binding domain Ubiquitin_4 PF18036.1 ORY48430.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain PHD PF00628.29 ORY48430.1 - 0.25 11.2 9.9 5.9 6.9 0.0 2.3 2 0 0 2 2 2 0 PHD-finger CEBP_ZZ PF16366.5 ORY48430.1 - 0.62 10.3 7.8 0.63 10.3 4.7 2.1 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain IBR PF01485.21 ORY48430.1 - 1.4 9.2 12.6 2.7 8.3 10.1 2.3 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain DZR PF12773.7 ORY48430.1 - 4.3 7.4 13.0 20 5.3 9.2 2.5 1 1 1 2 2 2 0 Double zinc ribbon Cation_efflux PF01545.21 ORY48431.1 - 1e-34 120.0 19.9 3.8e-34 118.2 19.9 1.8 1 1 0 1 1 1 1 Cation efflux family RseC_MucC PF04246.12 ORY48431.1 - 0.061 13.3 0.4 0.061 13.3 0.4 2.0 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC 7tm_1 PF00001.21 ORY48431.1 - 0.32 10.3 0.1 0.32 10.3 0.1 1.9 3 0 0 3 3 3 0 7 transmembrane receptor (rhodopsin family) ArfGap PF01412.18 ORY48432.1 - 1.1e-28 99.6 0.3 1.4e-28 99.3 0.3 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3973 PF13119.6 ORY48432.1 - 0.092 12.8 0.2 0.18 11.9 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3973) GATA PF00320.27 ORY48432.1 - 0.11 12.2 0.2 0.2 11.3 0.2 1.5 1 0 0 1 1 1 0 GATA zinc finger ATG22 PF11700.8 ORY48434.1 - 2.4e-72 244.1 9.2 1.5e-36 126.0 0.2 2.1 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like MFS_1 PF07690.16 ORY48434.1 - 0.00033 19.7 31.7 0.0016 17.4 7.5 3.2 1 1 1 3 3 3 3 Major Facilitator Superfamily MARVEL PF01284.23 ORY48434.1 - 3.5 7.6 19.5 0.12 12.4 8.4 3.3 2 1 2 4 4 4 0 Membrane-associating domain Glyco_transf_17 PF04724.13 ORY48435.1 - 3.7e-52 177.5 0.0 5.2e-34 117.8 0.1 2.9 1 1 0 2 2 2 2 Glycosyltransferase family 17 Glyco_transf_17 PF04724.13 ORY48436.1 - 5.4e-35 121.1 0.7 5.8e-33 114.4 0.1 3.0 2 1 0 2 2 2 1 Glycosyltransferase family 17 Peptidase_S51 PF03575.17 ORY48437.1 - 0.05 13.3 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 Peptidase family S51 Pec_lyase_N PF04431.13 ORY48437.1 - 0.11 12.8 1.6 0.43 10.9 0.3 2.7 2 0 0 2 2 2 0 Pectate lyase, N terminus Gmad1 PF10647.9 ORY48438.1 - 0.0096 15.7 0.0 0.01 15.6 0.0 1.1 1 0 0 1 1 1 1 Lipoprotein LpqB beta-propeller domain Coatomer_WDAD PF04053.14 ORY48438.1 - 0.049 12.7 0.0 0.066 12.3 0.0 1.3 1 1 0 1 1 1 0 Coatomer WD associated region WD40 PF00400.32 ORY48439.1 - 0.045 14.6 1.3 1.3 10.0 0.1 2.7 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF2173 PF09941.9 ORY48441.1 - 0.014 15.6 0.2 0.023 15.0 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2173) DUF2462 PF09495.10 ORY48441.1 - 0.058 14.1 14.6 0.1 13.3 2.5 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2462) AMP-binding PF00501.28 ORY48442.1 - 4.5e-90 302.3 0.0 5.9e-90 301.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY48442.1 - 0.018 16.0 0.3 0.049 14.6 0.3 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 ORY48443.1 - 7.4e-79 265.3 0.0 1.3e-78 264.5 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY48443.1 - 5.7e-05 24.0 0.2 0.0002 22.3 0.2 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 ORY48444.1 - 4.7e-91 305.5 0.0 6.4e-91 305.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY48444.1 - 0.00022 22.1 0.2 0.00086 20.2 0.2 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 5_nucleotid_C PF02872.18 ORY48445.1 - 9e-14 52.0 0.0 2.5e-13 50.5 0.0 1.7 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain EF-hand_7 PF13499.6 ORY48445.1 - 6.6e-08 32.9 0.2 1.9e-07 31.4 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 ORY48445.1 - 2.1e-07 30.0 1.0 0.002 17.6 0.2 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 ORY48445.1 - 1.1e-06 28.1 0.5 0.011 15.7 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 ORY48445.1 - 8.3e-05 22.4 0.1 0.00022 21.0 0.1 1.8 2 0 0 2 2 2 1 EF-hand domain pair Metallophos PF00149.28 ORY48445.1 - 0.066 13.7 0.2 0.77 10.2 0.1 2.6 2 2 1 3 3 3 0 Calcineurin-like phosphoesterase MauJ PF17419.2 ORY48445.1 - 0.091 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Methylamine utilization protein MauJ EF-hand_5 PF13202.6 ORY48445.1 - 1 9.0 2.8 4.4 7.0 0.1 2.7 3 0 0 3 3 3 0 EF hand Mito_carr PF00153.27 ORY48446.1 - 2.5e-37 126.7 2.2 6.7e-15 54.8 0.0 4.2 3 2 1 4 4 4 4 Mitochondrial carrier protein EB1 PF03271.17 ORY48447.1 - 5.9e-12 45.6 0.2 1.4e-11 44.4 0.2 1.7 1 0 0 1 1 1 1 EB1-like C-terminal motif DUF812 PF05667.11 ORY48447.1 - 0.0032 16.4 3.4 0.0036 16.3 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) ATG16 PF08614.11 ORY48447.1 - 0.0034 17.7 3.1 0.0056 16.9 3.1 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Syntaxin-6_N PF09177.11 ORY48447.1 - 0.035 14.7 0.9 0.035 14.7 0.9 1.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF4337 PF14235.6 ORY48447.1 - 0.073 13.2 3.3 0.11 12.6 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Ndc1_Nup PF09531.10 ORY48447.1 - 0.55 8.9 5.6 0.65 8.6 5.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup dCMP_cyt_deam_1 PF00383.23 ORY48448.1 - 3.3e-25 87.9 4.0 4.7e-25 87.4 4.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 ORY48448.1 - 1e-13 51.2 0.2 1.3e-13 50.8 0.2 1.2 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 ORY48448.1 - 0.0015 18.6 0.2 0.0026 17.9 0.2 1.4 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 ORY48448.1 - 0.019 15.1 0.1 0.036 14.2 0.1 1.4 1 0 0 1 1 1 0 APOBEC3 NAD1 PF18778.1 ORY48448.1 - 0.035 14.2 1.1 0.055 13.6 1.1 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 XOO_2897-deam PF14440.6 ORY48448.1 - 0.044 13.9 0.1 0.078 13.1 0.1 1.3 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase APOBEC4_like PF18774.1 ORY48448.1 - 0.058 13.3 0.1 0.094 12.7 0.1 1.3 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase APOBEC_N PF08210.11 ORY48448.1 - 0.082 12.8 1.4 0.17 11.7 1.3 1.5 1 1 0 1 1 1 0 APOBEC-like N-terminal domain ATG22 PF11700.8 ORY48449.1 - 1.4e-111 373.5 18.2 1.6e-111 373.3 18.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 ORY48449.1 - 2.3e-08 33.4 43.4 0.00023 20.2 16.2 3.3 2 2 1 3 3 3 3 Major Facilitator Superfamily DUF5504 PF17608.2 ORY48449.1 - 0.043 13.9 0.7 0.043 13.9 0.7 2.4 2 1 0 2 2 2 0 Family of unknown function (DUF5504) ATG22 PF11700.8 ORY48450.1 - 3.3e-203 675.7 48.3 1.7e-110 369.9 21.4 3.0 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_1 PF07690.16 ORY48450.1 - 4.5e-11 42.3 86.6 1.4e-08 34.0 23.6 4.5 3 2 2 5 5 5 5 Major Facilitator Superfamily COX2_TM PF02790.15 ORY48450.1 - 0.1 12.8 3.0 9.4 6.5 0.1 3.3 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain Germane PF10646.9 ORY48450.1 - 0.14 13.0 0.0 9.3 7.1 0.0 2.8 2 0 0 2 2 2 0 Sporulation and spore germination DUF2953 PF11167.8 ORY48450.1 - 0.25 11.5 2.2 47 4.2 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2953) 2OG-FeII_Oxy_2 PF13532.6 ORY48451.1 - 1.5e-17 64.5 0.0 1.6e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily IF-2B PF01008.17 ORY48452.1 - 8.3e-39 133.5 0.1 9.5e-39 133.3 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Cyt-b5 PF00173.28 ORY48454.1 - 7.7e-11 42.0 0.0 1.1e-10 41.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cyt-b5 PF00173.28 ORY48455.1 - 6.9e-10 38.9 0.0 1.2e-09 38.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Isy1 PF06246.12 ORY48456.1 - 1.2e-14 54.5 0.2 1.3e-14 54.4 0.2 1.0 1 0 0 1 1 1 1 Isy1-like splicing family Isy1 PF06246.12 ORY48457.1 - 2.8e-68 230.2 1.1 3.4e-68 230.0 1.1 1.0 1 0 0 1 1 1 1 Isy1-like splicing family GRAB PF10375.9 ORY48458.1 - 7.9e-08 31.9 0.6 1.4e-07 31.1 0.6 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain GRIP PF01465.20 ORY48458.1 - 2.3e-06 27.4 0.0 3.9e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 GRIP domain TolA_bind_tri PF16331.5 ORY48458.1 - 0.00017 21.6 0.5 0.00046 20.2 0.2 1.7 1 1 1 2 2 2 1 TolA binding protein trimerisation Tropomyosin PF00261.20 ORY48458.1 - 0.006 16.0 2.2 0.0099 15.3 2.2 1.3 1 0 0 1 1 1 1 Tropomyosin SOGA PF11365.8 ORY48458.1 - 0.0066 17.6 0.4 0.012 16.7 0.4 1.4 1 0 0 1 1 1 1 Protein SOGA Pox_A_type_inc PF04508.12 ORY48458.1 - 0.11 12.4 0.2 1.5 8.8 0.0 2.7 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat MscS_porin PF12795.7 ORY48458.1 - 0.17 11.4 7.1 0.24 10.9 7.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain GAS PF13851.6 ORY48459.1 - 8.3e-06 25.3 92.5 0.0063 15.9 10.9 7.2 4 3 2 6 6 6 5 Growth-arrest specific micro-tubule binding Filament PF00038.21 ORY48459.1 - 0.00014 21.6 26.1 0.00014 21.6 26.1 6.3 4 3 1 5 5 5 2 Intermediate filament protein CENP-F_leu_zip PF10473.9 ORY48459.1 - 0.00029 20.9 25.3 0.0023 18.0 10.3 7.9 4 3 3 7 7 6 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HAP1_N PF04849.13 ORY48459.1 - 0.00038 19.8 16.7 0.00038 19.8 16.7 6.5 3 2 3 6 6 6 1 HAP1 N-terminal conserved region Fez1 PF06818.15 ORY48459.1 - 0.0042 17.6 13.9 0.0042 17.6 13.9 4.9 3 2 1 4 4 4 2 Fez1 TMF_DNA_bd PF12329.8 ORY48459.1 - 0.012 15.6 9.9 0.012 15.6 9.9 10.4 5 4 5 11 11 11 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 ORY48459.1 - 0.025 14.8 124.6 0.085 13.1 20.0 7.1 2 2 4 6 6 5 0 Autophagy protein 16 (ATG16) CALCOCO1 PF07888.11 ORY48459.1 - 0.045 12.6 85.1 0.15 10.9 12.2 5.0 3 1 1 4 4 4 0 Calcium binding and coiled-coil domain (CALCOCO1) like bZIP_1 PF00170.21 ORY48459.1 - 0.071 13.2 0.1 0.071 13.2 0.1 9.6 8 2 2 10 10 10 0 bZIP transcription factor Spc7 PF08317.11 ORY48459.1 - 0.61 8.9 101.5 0.26 10.1 19.6 6.9 3 2 3 6 6 6 0 Spc7 kinetochore protein DUF1970 PF09301.10 ORY48459.1 - 0.77 10.0 2.8 4.2 7.7 0.2 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1970) FlaC_arch PF05377.11 ORY48459.1 - 1 9.8 47.7 1.5 9.3 0.0 9.8 7 3 2 9 9 9 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 ORY48459.1 - 1.8 8.6 59.0 0.11 12.5 4.9 7.9 4 3 4 9 9 9 0 Protein of unknown function (DUF1664) MscS_porin PF12795.7 ORY48459.1 - 1.8 8.1 117.9 0.25 10.9 44.1 5.9 3 1 2 5 5 5 0 Mechanosensitive ion channel porin domain DUF4407 PF14362.6 ORY48459.1 - 2.4 7.4 77.6 0.03 13.7 2.8 6.0 2 2 3 5 5 5 0 Domain of unknown function (DUF4407) Cnn_1N PF07989.11 ORY48459.1 - 4.5 7.5 66.3 0.092 12.9 4.0 9.8 6 2 3 9 9 9 0 Centrosomin N-terminal motif 1 PspA_IM30 PF04012.12 ORY48459.1 - 4.6 6.7 93.1 0.26 10.8 19.4 6.2 4 2 1 5 5 4 0 PspA/IM30 family LUC7 PF03194.15 ORY48460.1 - 1.6e-20 73.8 1.7 2.3e-20 73.3 1.7 1.2 1 0 0 1 1 1 1 LUC7 N_terminus Cyt-b5 PF00173.28 ORY48460.1 - 5.9e-05 23.1 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NosD PF05048.13 ORY48461.1 - 0.087 12.1 9.8 0.0086 15.4 3.9 2.0 2 1 1 3 3 3 0 Periplasmic copper-binding protein (NosD) Chlam_PMP PF02415.17 ORY48461.1 - 0.11 13.1 0.9 0.11 13.1 0.9 6.8 8 0 0 8 8 8 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat End_beta_barrel PF12195.8 ORY48463.1 - 0.63 10.0 7.3 0.21 11.5 0.6 2.6 2 1 1 3 3 3 0 Beta barrel domain of bacteriophage endosialidase LRR_4 PF12799.7 ORY48464.1 - 4.1e-12 46.1 32.1 0.00013 22.2 6.3 7.6 4 2 5 9 9 9 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY48464.1 - 6.3e-06 25.8 12.7 1.5 9.1 0.3 6.1 5 0 0 5 5 5 4 Leucine Rich repeat LRR_8 PF13855.6 ORY48464.1 - 0.00037 20.2 6.7 0.00037 20.2 6.7 5.8 3 2 2 5 5 5 2 Leucine rich repeat LRR_1 PF00560.33 ORY48464.1 - 0.0013 19.0 17.2 0.38 11.5 0.1 7.2 5 2 1 6 6 6 2 Leucine Rich Repeat FNIP PF05725.12 ORY48464.1 - 0.45 10.7 24.3 12 6.1 3.8 6.8 5 3 0 5 5 5 0 FNIP Repeat HTH_23 PF13384.6 ORY48465.1 - 0.0016 18.2 0.0 0.0053 16.5 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 ORY48465.1 - 0.012 15.6 0.0 0.047 13.7 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn helix Terminase_5 PF06056.12 ORY48465.1 - 0.013 15.4 0.1 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) DUF4817 PF16087.5 ORY48465.1 - 0.033 14.0 3.6 0.051 13.4 1.4 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain (DUF4817) Phage_antitermQ PF06530.12 ORY48465.1 - 0.068 13.1 0.2 0.15 12.0 0.1 1.8 1 1 1 2 2 2 0 Phage antitermination protein Q LRR_4 PF12799.7 ORY48466.1 - 7.7e-07 29.3 19.2 0.53 10.8 0.5 6.9 5 2 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY48466.1 - 2.2 8.1 15.5 2.5 7.9 0.4 5.0 5 2 1 6 6 6 0 Leucine rich repeat LRR_1 PF00560.33 ORY48466.1 - 2.3 9.1 15.2 0.75 10.6 0.7 6.0 7 0 0 7 7 7 0 Leucine Rich Repeat FNIP PF05725.12 ORY48466.1 - 5.2 7.3 20.7 6.3 7.1 0.7 5.4 3 2 2 5 5 5 0 FNIP Repeat NIF PF03031.18 ORY48467.1 - 2.1e-20 73.1 0.0 3e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ATP-synt_ab PF00006.25 ORY48468.1 - 5.2e-68 228.9 0.0 7.3e-68 228.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 ORY48468.1 - 2.9e-13 50.1 0.6 5.7e-13 49.2 0.6 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3533 PF12051.8 ORY48468.1 - 0.03 13.2 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) SBDS PF01172.18 ORY48469.1 - 2.3e-13 50.0 0.3 2.8e-13 49.7 0.3 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein HrpE PF06188.12 ORY48469.1 - 0.072 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E Tcp11 PF05794.13 ORY48470.1 - 5.5e-78 263.0 2.1 9.6e-78 262.2 0.0 2.3 3 0 0 3 3 3 1 T-complex protein 11 FAD_binding_6 PF00970.24 ORY48471.1 - 2.6e-12 46.9 0.0 5e-12 46.0 0.0 1.4 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ORY48471.1 - 4.9e-09 36.8 0.0 8.3e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 ORY48471.1 - 2.2e-05 24.6 0.0 3.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain AA_permease_2 PF13520.6 ORY48472.1 - 2.9e-22 79.1 54.0 4e-22 78.6 54.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY48472.1 - 3.2e-10 39.2 45.9 4.6e-10 38.7 45.9 1.2 1 0 0 1 1 1 1 Amino acid permease TFIIA PF03153.13 ORY48473.1 - 9.3 6.1 20.6 13 5.7 20.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4816 PF16086.5 ORY48475.1 - 0.06 13.3 4.4 0.085 12.8 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4816) LRR_4 PF12799.7 ORY48476.1 - 0.0004 20.7 32.3 15 6.1 0.0 8.0 3 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY48476.1 - 2.4 8.0 22.0 2.4 8.0 6.8 5.2 4 2 1 5 5 5 0 Leucine rich repeat LRR_1 PF00560.33 ORY48476.1 - 8.2 7.4 10.4 7.6 7.5 0.0 5.8 3 2 1 4 4 4 0 Leucine Rich Repeat Dioxygenase_C PF00775.21 ORY48477.1 - 1.8e-07 30.8 0.0 8.2e-06 25.4 0.0 2.4 2 0 0 2 2 2 2 Dioxygenase TFIIA PF03153.13 ORY48478.1 - 2.8 7.9 27.1 3.6 7.5 27.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 ORY48479.1 - 0.08 12.5 2.7 0.092 12.3 2.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ndc1_Nup PF09531.10 ORY48479.1 - 0.9 8.1 4.8 0.88 8.2 4.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MFS_1 PF07690.16 ORY48481.1 - 7.4e-27 94.2 21.8 8.9e-27 93.9 21.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 ORY48481.1 - 3.7e-09 36.4 5.7 4.9e-09 36.0 5.7 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 ORY48481.1 - 7.2e-06 24.8 9.1 8.2e-06 24.6 9.1 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein Sugar_tr PF00083.24 ORY48481.1 - 2.9e-05 23.1 15.7 0.00053 19.0 14.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter PUCC PF03209.15 ORY48481.1 - 0.0054 15.8 9.2 1.1 8.2 7.3 2.2 1 1 1 2 2 2 2 PUCC protein DUF4220 PF13968.6 ORY48481.1 - 0.0086 15.5 0.5 0.013 14.9 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4220) DUF4396 PF14342.6 ORY48481.1 - 0.013 15.8 2.8 0.013 15.8 2.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4396) DUF2417 PF10329.9 ORY48481.1 - 0.39 10.1 2.7 0.84 9.0 2.6 1.5 1 1 0 1 1 1 0 Region of unknown function (DUF2417) OATP PF03137.20 ORY48481.1 - 2.6 6.2 9.1 19 3.4 9.1 2.0 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family HEAT PF02985.22 ORY48482.1 - 2.6e-34 114.3 15.9 0.00077 19.5 0.0 18.6 21 0 0 21 21 19 7 HEAT repeat Gcn1_N PF12074.8 ORY48482.1 - 4.7e-33 115.0 6.2 1.3e-32 113.5 4.7 2.8 2 1 0 2 2 2 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT_EZ PF13513.6 ORY48482.1 - 7.5e-19 67.8 36.6 0.013 16.0 0.1 16.2 13 3 4 17 17 16 4 HEAT-like repeat HEAT_2 PF13646.6 ORY48482.1 - 7.6e-19 67.9 22.2 0.00076 19.8 1.0 11.4 9 1 1 11 11 11 4 HEAT repeats Cnd1 PF12717.7 ORY48482.1 - 8.4e-13 48.7 1.2 0.0023 18.0 0.0 9.0 5 4 3 8 8 8 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 ORY48482.1 - 1.1e-08 35.0 0.0 4.9e-05 23.0 0.0 5.8 5 1 2 7 7 7 1 CLASP N terminal Adaptin_N PF01602.20 ORY48482.1 - 3.3e-07 29.3 11.4 0.0012 17.6 0.0 6.7 6 2 2 8 8 8 3 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 ORY48482.1 - 8.1e-06 26.3 0.4 19 5.9 0.0 6.8 7 2 0 7 7 5 0 Vacuolar 14 Fab1-binding region UME PF08064.13 ORY48482.1 - 2.2e-05 24.3 11.6 1.9 8.4 0.0 8.4 10 0 0 10 10 9 2 UME (NUC010) domain ParcG PF10274.9 ORY48482.1 - 2.6e-05 24.4 2.4 0.13 12.4 0.0 5.2 4 2 2 6 6 6 1 Parkin co-regulated protein Tuberin PF03542.16 ORY48482.1 - 0.00086 18.5 0.1 0.0022 17.2 0.1 1.6 1 0 0 1 1 1 1 Tuberin TFCD_C PF12612.8 ORY48482.1 - 0.0054 16.6 2.5 0.19 11.6 0.9 3.3 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal Cohesin_HEAT PF12765.7 ORY48482.1 - 0.041 14.2 0.2 0.85 10.0 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion WXG100 PF06013.12 ORY48482.1 - 0.13 12.5 1.4 0.37 11.0 0.1 2.6 2 0 0 2 2 1 0 Proteins of 100 residues with WXG UQ_con PF00179.26 ORY48483.1 - 1.9e-41 141.0 0.0 2.1e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 ORY48483.1 - 0.056 13.1 0.0 0.079 12.7 0.0 1.5 1 1 0 1 1 1 0 Prokaryotic E2 family B AlaDh_PNT_N PF05222.15 ORY48484.1 - 2.1e-30 105.8 0.0 4e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 ORY48484.1 - 0.0027 17.0 0.0 0.0065 15.8 0.0 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ANF_receptor PF01094.28 ORY48485.1 - 7e-10 38.5 0.0 1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region RRM_DME PF15628.6 ORY48485.1 - 0.12 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 RRM in Demeter 7tm_3 PF00003.22 ORY48486.1 - 2.7e-11 43.6 18.9 4.1e-11 43.1 18.9 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ubiquitin PF00240.23 ORY48488.1 - 1.6e-08 34.2 0.0 1.4e-07 31.1 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 ORY48488.1 - 1.8e-05 24.5 0.0 3.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PRIMA1 PF16101.5 ORY48488.1 - 0.015 15.4 7.5 0.015 15.4 7.5 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 SWIRM-assoc_2 PF16496.5 ORY48488.1 - 0.32 9.8 3.0 0.56 9.0 3.0 1.3 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal DUF2306 PF10067.9 ORY48489.1 - 2.2e-16 60.4 7.9 2.2e-16 60.4 7.9 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) FAD_binding_6 PF00970.24 ORY48489.1 - 4.9e-15 55.7 0.0 9.4e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ORY48489.1 - 3.6e-11 43.7 0.0 6.7e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 ORY48489.1 - 2.9e-06 27.5 0.0 4.6e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DnaJ_C PF01556.18 ORY48490.1 - 5.6e-37 127.1 1.2 6.6e-37 126.9 1.2 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain PhyH PF05721.13 ORY48491.1 - 3.9e-12 46.9 0.0 6.6e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) GFO_IDH_MocA PF01408.22 ORY48492.1 - 2.7e-21 76.6 0.0 4.6e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 ORY48492.1 - 0.055 14.1 0.8 0.17 12.5 0.4 2.1 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 ORY48492.1 - 0.1 12.8 0.1 10 6.4 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Peptidase_S9 PF00326.21 ORY48493.1 - 2.7e-14 53.1 0.0 4.9e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 ORY48493.1 - 2e-05 24.3 0.0 3.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 ORY48493.1 - 0.12 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative esterase zf-LITAF-like PF10601.9 ORY48496.1 - 8e-17 61.3 11.7 1.4e-16 60.5 11.7 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain DSS1_SEM1 PF05160.13 ORY48498.1 - 8.7e-12 44.9 13.0 1.2e-11 44.4 13.0 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family DUF4872 PF16169.5 ORY48498.1 - 0.03 14.1 0.2 0.038 13.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4872) Cwf_Cwc_15 PF04889.12 ORY48499.1 - 1 9.0 12.2 3.1 7.5 3.2 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Gti1_Pac2 PF09729.9 ORY48500.1 - 1.3e-22 80.8 0.0 2.2e-19 70.2 0.0 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family Acetyltransf_3 PF13302.7 ORY48502.1 - 7.7e-20 72.0 0.0 9.7e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY48502.1 - 3.9e-06 27.1 0.0 5.4e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 ORY48502.1 - 9.5e-05 22.1 0.3 0.00076 19.2 0.3 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 ORY48502.1 - 0.0032 17.6 0.0 0.0062 16.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY48502.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Transket_pyr PF02779.24 ORY48503.1 - 1e-59 201.2 0.0 1.5e-59 200.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 ORY48503.1 - 2.3e-48 163.8 0.0 3.8e-48 163.0 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 ORY48503.1 - 5.2e-47 160.2 0.0 7.9e-47 159.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Acyl-CoA_dh_1 PF00441.24 ORY48504.1 - 7.2e-50 169.1 3.7 1.2e-49 168.4 3.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 ORY48504.1 - 1.2e-24 87.1 0.1 2.6e-24 86.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 ORY48504.1 - 5.7e-24 84.1 0.2 1.4e-23 82.9 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 ORY48504.1 - 3.6e-21 75.8 1.7 7.3e-21 74.8 1.7 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 ORY48504.1 - 0.065 12.9 0.0 0.16 11.6 0.0 1.7 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Nexin_C PF08628.12 ORY48505.1 - 2.2e-15 57.2 0.3 8.6e-15 55.3 0.1 2.0 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 ORY48505.1 - 0.0044 17.0 3.5 0.0067 16.4 0.2 2.4 2 1 0 2 2 2 1 PX domain PXA PF02194.15 ORY48506.1 - 5.2e-22 78.7 0.2 2.3e-21 76.6 0.1 2.2 2 0 0 2 2 2 1 PXA domain ELP6 PF09807.9 ORY48506.1 - 0.034 13.6 1.3 0.17 11.3 0.1 2.3 2 0 0 2 2 2 0 Elongation complex protein 6 MutS_V PF00488.21 ORY48506.1 - 0.085 12.9 1.9 0.87 9.6 0.1 2.6 3 0 0 3 3 3 0 MutS domain V PEP-utilisers_N PF05524.13 ORY48506.1 - 0.14 12.3 0.9 26 5.0 0.0 3.3 3 0 0 3 3 3 0 PEP-utilising enzyme, N-terminal cNMP_binding PF00027.29 ORY48507.1 - 1.8e-15 56.7 0.0 4.1e-15 55.6 0.0 1.6 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 ORY48507.1 - 0.021 14.8 0.3 0.045 13.7 0.3 1.5 1 0 0 1 1 1 0 Ion channel ubiquitin PF00240.23 ORY48510.1 - 2.5e-08 33.6 0.0 4.4e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY48510.1 - 7.1e-06 25.8 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Herpes_ORF11 PF04797.13 ORY48510.1 - 0.05 12.4 0.0 0.069 11.9 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus dUTPase protein Ubiquitin_4 PF18036.1 ORY48510.1 - 0.21 11.7 0.0 1.1 9.4 0.0 1.9 1 1 1 2 2 2 0 Ubiquitin-like domain Sacchrp_dh_NADP PF03435.18 ORY48511.1 - 4.7e-18 65.7 1.1 7.4e-18 65.1 1.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 ORY48511.1 - 0.015 14.3 0.2 0.022 13.8 0.2 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 ORY48511.1 - 0.086 12.4 1.3 0.15 11.6 1.3 1.4 1 0 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.6 ORY48511.1 - 0.1 12.5 4.4 0.26 11.2 4.4 1.8 1 1 0 1 1 1 0 NAD(P)H-binding DUF561 PF04481.12 ORY48511.1 - 0.12 11.5 0.2 0.24 10.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF561) cNMP_binding PF00027.29 ORY48514.1 - 2.1e-14 53.3 0.0 5e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain RE_HaeII PF09554.10 ORY48514.1 - 0.045 13.0 0.2 0.16 11.2 0.1 1.8 1 1 1 2 2 2 0 HaeII restriction endonuclease AHSP PF09236.10 ORY48514.1 - 0.16 12.5 1.1 0.37 11.2 0.4 1.9 2 0 0 2 2 2 0 Alpha-haemoglobin stabilising protein SIS PF01380.22 ORY48515.1 - 1.2e-64 216.0 0.1 1.6e-34 118.6 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 ORY48515.1 - 9.2e-18 64.7 0.0 1.9e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 ORY48515.1 - 7.7e-14 51.7 0.0 1.8e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 ORY48515.1 - 1.4e-05 24.2 0.0 2.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.21 ORY48515.1 - 0.00057 18.7 0.0 0.0023 16.7 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 ORY48515.1 - 0.033 14.2 0.0 0.21 11.6 0.0 2.4 2 0 0 2 2 2 0 SIS domain PCI PF01399.27 ORY48516.1 - 3.9e-11 43.4 0.0 6.6e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.17 ORY48516.1 - 0.0016 18.4 4.9 5.7 7.3 0.7 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat DUF1275 PF06912.11 ORY48517.1 - 6.7e-30 104.4 19.4 8.3e-30 104.2 19.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) PIG-P PF08510.12 ORY48517.1 - 0.002 18.1 0.2 0.49 10.3 0.0 3.2 2 1 1 3 3 3 1 PIG-P LapA_dom PF06305.11 ORY48517.1 - 0.16 11.8 0.4 1.9 8.4 0.3 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DDE_3 PF13358.6 ORY48519.1 - 1.9e-06 27.7 0.2 2.5e-06 27.3 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Rhodanese PF00581.20 ORY48521.1 - 0.0052 17.3 0.0 0.0097 16.4 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain LMWPc PF01451.21 ORY48522.1 - 2e-20 73.6 0.0 2.5e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase SBF PF01758.16 ORY48523.1 - 5e-47 160.1 12.2 1.1e-46 159.0 12.2 1.5 1 0 0 1 1 1 1 Sodium Bile acid symporter family AMP-binding PF00501.28 ORY48525.1 - 5.7e-14 51.5 0.3 2.1e-13 49.7 0.3 1.9 1 1 0 1 1 1 1 AMP-binding enzyme Hexapep PF00132.24 ORY48525.1 - 6.5e-11 41.5 11.3 3.4e-07 29.7 1.1 5.9 6 0 0 6 6 6 2 Bacterial transferase hexapeptide (six repeats) PP-binding PF00550.25 ORY48525.1 - 4.2e-10 39.8 0.0 7.8e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hexapep_2 PF14602.6 ORY48525.1 - 0.0011 18.6 2.3 0.0011 18.6 2.3 5.5 6 0 0 6 6 6 1 Hexapeptide repeat of succinyl-transferase AMP-binding_C PF13193.6 ORY48525.1 - 0.0074 17.2 0.1 0.02 15.9 0.1 1.8 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 ORY48526.1 - 7.9e-09 34.6 0.0 1.3e-08 33.9 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme Glyco_trans_4_5 PF16994.5 ORY48526.1 - 0.1 12.2 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Glycosyl-transferase family 4 GH3 PF03321.13 ORY48526.1 - 0.18 10.6 0.2 0.28 10.0 0.2 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter RepB-RCR_reg PF10723.9 ORY48526.1 - 0.26 11.2 0.9 4.1 7.4 0.1 2.8 3 1 0 3 3 3 0 Replication regulatory protein RepB Med20 PF08612.11 ORY48527.1 - 6e-17 61.8 0.0 6.8e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex NAGPA PF09992.9 ORY48527.1 - 0.026 14.7 0.1 0.04 14.1 0.1 1.5 1 1 0 1 1 1 0 Phosphodiester glycosidase zf-Tim10_DDP PF02953.15 ORY48529.1 - 2.4e-14 52.7 0.3 3.1e-14 52.4 0.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Methyltransf_25 PF13649.6 ORY48530.1 - 1.7e-16 60.7 0.0 2.8e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY48530.1 - 9.9e-16 57.9 0.0 1.3e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY48530.1 - 2.1e-14 54.0 0.0 3.3e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY48530.1 - 1.1e-11 45.4 0.0 1.8e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY48530.1 - 4.9e-11 42.5 0.0 7e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 ORY48530.1 - 9e-11 41.9 0.0 1.4e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ORY48530.1 - 3.3e-05 23.3 0.0 4.5e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 ORY48530.1 - 0.00015 21.2 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_17 PF12692.7 ORY48530.1 - 0.00033 20.7 0.0 0.00045 20.3 0.0 1.2 1 0 0 1 1 1 1 S-adenosyl-L-methionine methyltransferase CMAS PF02353.20 ORY48530.1 - 0.0016 17.8 0.0 0.0022 17.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 ORY48530.1 - 0.0095 15.4 0.0 0.036 13.5 0.0 1.9 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.6 ORY48530.1 - 0.01 15.8 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 ORY48530.1 - 0.045 13.2 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB CheR PF01739.18 ORY48530.1 - 0.046 13.2 0.0 1.1 8.8 0.0 2.2 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain UPF0020 PF01170.18 ORY48530.1 - 0.074 12.7 0.0 0.16 11.6 0.0 1.5 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 DREV PF05219.12 ORY48530.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase OsmC PF02566.19 ORY48531.1 - 6.1e-11 42.7 0.0 8.7e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein Phenol_MetA_deg PF13557.6 ORY48531.1 - 0.0064 16.5 0.0 0.0067 16.4 0.0 1.2 1 0 0 1 1 1 1 Putative MetA-pathway of phenol degradation WD40 PF00400.32 ORY48532.1 - 2.5e-28 97.7 10.5 2.2e-07 31.4 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 ORY48532.1 - 3.9e-28 97.5 0.2 1.2e-27 96.0 0.2 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 ORY48532.1 - 0.00022 21.4 2.6 0.52 10.6 0.1 4.0 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY48532.1 - 0.0012 18.8 1.7 0.018 14.9 0.1 2.7 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DNA_methylase PF00145.17 ORY48534.1 - 7.6e-29 101.1 0.0 3e-28 99.1 0.0 1.8 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase DUF3510 PF12022.8 ORY48535.1 - 6.3e-16 58.9 0.1 2.5e-15 57.0 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) COG2 PF06148.11 ORY48535.1 - 1e-15 58.0 0.0 2.6e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 UCR_14kD PF02271.16 ORY48536.1 - 1.3e-27 95.6 0.0 1.7e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Ribonuc_red_lgC PF02867.15 ORY48537.1 - 7.1e-191 635.3 0.0 9.8e-191 634.8 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain ASH PF15780.5 ORY48537.1 - 1.5e-37 127.8 16.8 0.013 15.7 0.0 18.5 19 1 0 19 19 19 10 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 ORY48537.1 - 3e-25 88.2 5.2 1.7e-05 24.6 0.2 9.5 9 0 0 9 9 9 5 MSP (Major sperm protein) domain Ribonuc_red_lgN PF00317.21 ORY48537.1 - 3.2e-22 78.3 0.0 8.4e-22 77.0 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain DUF1573 PF07610.11 ORY48537.1 - 9.3e-17 60.9 5.8 0.59 10.2 0.1 14.6 15 1 0 15 15 15 3 Protein of unknown function (DUF1573) ATP-cone PF03477.16 ORY48537.1 - 3e-16 59.8 0.0 8.1e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 ATP cone domain TMEM131_like PF12371.8 ORY48537.1 - 3.4e-06 27.2 10.1 1.6 9.0 0.0 9.8 11 0 0 11 11 11 1 Transmembrane protein 131-like PapD-like PF14874.6 ORY48537.1 - 3.2e-05 24.0 0.8 0.11 12.6 0.0 6.4 8 0 0 8 8 8 1 Flagellar-associated PapD-like DUF756 PF05506.12 ORY48537.1 - 0.0027 18.6 0.0 0.72 10.8 0.0 4.2 4 0 0 4 4 4 1 Domain of unknown function (DUF756) MYCBPAP PF14646.6 ORY48537.1 - 0.02 13.9 0.1 15 4.4 0.0 4.5 5 1 0 5 5 5 0 MYCBP-associated protein family tRNA-synt_2c PF01411.19 ORY48539.1 - 4.9e-216 718.5 0.0 6.5e-216 718.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 ORY48539.1 - 4.9e-17 61.7 0.5 2e-16 59.8 0.1 2.3 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 ORY48539.1 - 1.7e-13 51.2 9.3 4.6e-13 49.8 9.3 1.8 1 0 0 1 1 1 1 DHHA1 domain RIIa PF02197.17 ORY48540.1 - 0.1 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit zf-MYND PF01753.18 ORY48541.1 - 9.9e-09 35.2 17.1 1.7e-08 34.4 17.1 1.4 1 0 0 1 1 1 1 MYND finger NDUF_B7 PF05676.13 ORY48542.1 - 0.14 11.9 4.3 0.27 11.0 0.5 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) SART-1 PF03343.13 ORY48543.1 - 3.4e-118 395.9 67.9 3.4e-118 395.9 67.9 1.6 2 0 0 2 2 2 1 SART-1 family Orthopox_A36R PF05950.11 ORY48543.1 - 0.02 15.1 0.4 0.062 13.5 0.4 1.9 1 0 0 1 1 1 0 Orthopoxvirus A36R protein LRR_8 PF13855.6 ORY48544.1 - 3.3e-12 46.0 0.3 1.3e-07 31.3 0.1 3.0 1 1 2 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 ORY48544.1 - 5.3e-10 39.4 0.1 0.022 15.2 0.1 3.8 1 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY48544.1 - 4.4e-06 26.5 0.1 6.7 7.7 0.0 5.4 5 0 0 5 5 5 1 Leucine Rich Repeat F-box PF00646.33 ORY48544.1 - 0.00012 21.9 0.1 0.00034 20.4 0.1 1.8 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.6 ORY48544.1 - 0.0052 16.7 0.4 6 7.2 0.0 3.1 3 0 0 3 3 3 2 Leucine Rich repeat F-box-like PF12937.7 ORY48544.1 - 0.049 13.5 0.3 0.096 12.6 0.3 1.5 1 0 0 1 1 1 0 F-box-like MMgT PF10270.9 ORY48545.1 - 3.9e-11 43.2 0.0 4.9e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter Pcc1 PF09341.10 ORY48546.1 - 1e-12 48.0 0.8 1.5e-12 47.5 0.8 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 Glyco_transf_90 PF05686.12 ORY48547.1 - 0.0022 17.0 0.1 0.22 10.4 0.0 3.0 2 1 0 2 2 2 2 Glycosyl transferase family 90 ABC_membrane_2 PF06472.15 ORY48548.1 - 2.1e-41 142.1 8.0 3.6e-31 108.6 0.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region 2 ABC_tran PF00005.27 ORY48548.1 - 8.8e-20 71.6 0.0 2e-19 70.4 0.0 1.6 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 ORY48548.1 - 0.0021 18.0 0.1 0.0071 16.3 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 ORY48548.1 - 0.0044 16.7 0.1 0.014 15.1 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 ORY48548.1 - 0.01 15.7 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORY48548.1 - 0.036 14.5 0.1 0.087 13.2 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 ORY48548.1 - 0.05 13.5 0.0 0.35 10.8 0.0 2.4 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 ORY48548.1 - 0.088 12.9 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 ORY48548.1 - 0.11 12.8 0.1 0.38 11.0 0.1 1.9 1 0 0 1 1 1 0 AAA domain ABC_membrane PF00664.23 ORY48548.1 - 9.2 5.8 10.9 12 5.4 1.0 2.5 2 1 0 2 2 2 0 ABC transporter transmembrane region DUF383 PF04063.14 ORY48549.1 - 5.2e-46 156.7 0.0 9.4e-46 155.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF383) CCDC24 PF15669.5 ORY48551.1 - 3.5e-14 53.1 2.5 4.7e-14 52.7 2.5 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 24 family Glyco_tranf_2_5 PF13712.6 ORY48551.1 - 0.011 15.5 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family NPR1_interact PF15699.5 ORY48551.1 - 0.053 14.1 0.1 0.073 13.7 0.1 1.2 1 0 0 1 1 1 0 NPR1 interacting NLRC4_HD PF17889.1 ORY48551.1 - 0.11 12.9 0.5 0.26 11.7 0.3 1.8 1 1 1 2 2 2 0 NLRC4 helical domain TMPIT PF07851.13 ORY48551.1 - 0.19 10.9 2.0 0.22 10.7 2.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein LRR_4 PF12799.7 ORY48552.1 - 6e-09 36.0 11.9 0.076 13.5 0.9 6.6 3 2 4 8 8 8 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY48552.1 - 7.2e-08 31.9 6.9 0.0056 16.6 0.1 6.4 7 0 0 7 7 7 3 Leucine Rich repeat LRR_2 PF07723.13 ORY48552.1 - 2.4 9.0 6.2 1.1e+02 3.7 0.0 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat Glyco_hydro_26 PF02156.15 ORY48553.1 - 5.7e-06 26.0 3.8 0.0001 21.9 3.7 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 26 Glyco_hydro_26 PF02156.15 ORY48554.1 - 0.00016 21.2 0.0 0.00022 20.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Glyco_hydro_26 PF02156.15 ORY48555.1 - 0.00025 20.6 6.6 0.00089 18.8 3.9 2.4 2 1 0 2 2 2 1 Glycosyl hydrolase family 26 APH PF01636.23 ORY48556.1 - 8.9e-43 146.9 0.0 1.1e-42 146.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY48556.1 - 1.5e-06 27.9 0.0 2.5e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 ORY48556.1 - 0.00021 20.7 0.0 0.00046 19.6 0.0 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase Ssu72 PF04722.13 ORY48557.1 - 6.1e-78 260.8 0.0 7.2e-78 260.5 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein DUF5414 PF17435.2 ORY48557.1 - 0.026 14.2 0.1 0.046 13.4 0.1 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5414) 6PF2K PF01591.18 ORY48558.1 - 1.6e-47 161.7 2.8 1.3e-44 152.1 2.8 3.1 1 1 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 ORY48558.1 - 5.9e-31 107.7 0.0 1.3e-29 103.3 0.0 2.8 3 1 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) 6PF2K PF01591.18 ORY48559.1 - 0.0043 16.4 0.0 0.0055 16.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase GAF PF01590.26 ORY48560.1 - 2.2e-18 67.2 0.0 3.9e-17 63.1 0.0 2.5 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.6 ORY48560.1 - 7.8e-09 36.0 0.0 2.4e-07 31.1 0.0 2.9 3 1 0 3 3 3 1 GAF domain Guanylate_cyc PF00211.20 ORY48560.1 - 5.7e-07 29.3 0.0 4.2e-05 23.2 0.0 2.4 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain GAF_3 PF13492.6 ORY48560.1 - 2.2e-06 28.0 0.0 5.7e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 GAF domain TPR_2 PF07719.17 ORY48560.1 - 0.029 14.5 0.0 0.057 13.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat RNA_pol_3_Rpc31 PF11705.8 ORY48560.1 - 1.2 9.4 12.9 2.2 8.5 12.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 BAALC_N PF06989.12 ORY48561.1 - 0.096 13.0 1.3 0.17 12.2 0.0 2.1 2 0 0 2 2 2 0 BAALC N-terminus Phosphorylase PF00343.20 ORY48562.1 - 3.9e-254 845.2 7.9 3.1e-130 435.7 0.1 4.0 1 1 1 2 2 2 2 Carbohydrate phosphorylase Herpes_glycoH_C PF17488.2 ORY48563.1 - 0.19 11.5 1.6 0.58 9.9 0.8 2.1 1 1 1 2 2 2 0 Herpesvirus glycoprotein H C-terminal domain YTH PF04146.15 ORY48566.1 - 1.5e-40 138.9 1.1 7.4e-40 136.6 0.1 2.4 2 1 0 2 2 2 1 YT521-B-like domain RRM_1 PF00076.22 ORY48566.1 - 0.0043 16.8 0.1 0.015 15.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tim17 PF02466.19 ORY48568.1 - 3.5e-09 37.0 0.3 6.6e-06 26.5 0.2 2.6 2 1 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family TMEM135_C_rich PF15982.5 ORY48568.1 - 4.3e-05 24.1 0.1 0.00012 22.7 0.1 1.7 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 CPBP PF02517.16 ORY48568.1 - 1.2 9.6 8.6 0.34 11.3 0.4 3.0 2 2 0 2 2 2 0 CPBP intramembrane metalloprotease Peptidase_M22 PF00814.25 ORY48569.1 - 3.5e-90 302.4 0.0 4.2e-90 302.1 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family CM_1 PF07736.11 ORY48569.1 - 0.014 15.8 0.0 0.044 14.2 0.0 1.8 2 0 0 2 2 2 0 Chorismate mutase type I Carbam_trans_N PF02543.15 ORY48569.1 - 0.058 13.1 0.0 0.1 12.2 0.0 1.4 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus Filo_VP35 PF02097.15 ORY48569.1 - 0.06 12.4 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 Filoviridae VP35 Thioredoxin_8 PF13905.6 ORY48570.1 - 1.1e-29 102.6 0.1 2.7e-23 82.1 0.0 3.7 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.6 ORY48570.1 - 1.9e-09 37.9 1.8 1.6e-07 31.7 0.0 3.6 4 0 0 4 4 4 1 Thioredoxin-like domain AhpC-TSA PF00578.21 ORY48570.1 - 1.6e-08 34.5 0.1 8.8e-07 28.9 0.0 3.1 2 1 0 2 2 2 1 AhpC/TSA family Thioredoxin PF00085.20 ORY48570.1 - 3.2e-08 33.5 0.0 0.00022 21.1 0.0 2.7 1 1 1 2 2 2 2 Thioredoxin Redoxin PF08534.10 ORY48570.1 - 4.8e-07 29.6 0.0 9.7e-06 25.4 0.0 2.6 2 0 0 2 2 2 1 Redoxin ZZ PF00569.17 ORY48570.1 - 6.5e-05 22.7 10.1 0.00012 21.8 10.1 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Thioredoxin_6 PF13848.6 ORY48570.1 - 0.00048 20.1 0.0 0.0029 17.6 0.0 2.2 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 ORY48570.1 - 0.00095 18.9 0.0 0.54 10.0 0.0 2.8 1 1 1 2 2 2 2 Thioredoxin C1_2 PF03107.16 ORY48570.1 - 0.003 17.8 6.0 0.0066 16.7 6.0 1.6 1 0 0 1 1 1 1 C1 domain Thioredoxin_7 PF13899.6 ORY48570.1 - 0.012 15.7 1.1 0.054 13.7 0.0 2.7 3 0 0 3 3 3 0 Thioredoxin-like Cript PF10235.9 ORY48570.1 - 0.036 14.6 1.5 0.13 12.8 1.5 1.9 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT Thioredoxin_8 PF13905.6 ORY48571.1 - 1.3e-29 102.4 0.0 4.4e-22 78.2 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 ORY48571.1 - 5.5e-10 39.7 0.0 4.2e-09 36.8 0.0 2.5 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin PF00085.20 ORY48571.1 - 2.2e-07 30.8 0.0 0.00043 20.2 0.0 2.6 1 1 1 2 2 2 2 Thioredoxin AhpC-TSA PF00578.21 ORY48571.1 - 1.7e-06 28.0 0.1 0.00013 21.9 0.0 2.8 3 0 0 3 3 3 1 AhpC/TSA family Redoxin PF08534.10 ORY48571.1 - 5.1e-05 23.0 0.0 0.00075 19.2 0.0 2.3 2 0 0 2 2 2 1 Redoxin Thioredoxin_9 PF14595.6 ORY48571.1 - 0.0014 18.4 0.0 0.11 12.2 0.0 2.9 2 1 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 ORY48571.1 - 0.015 15.2 0.9 0.6 10.0 0.0 3.6 4 1 0 5 5 5 0 Thioredoxin-like domain Thioredoxin_7 PF13899.6 ORY48571.1 - 0.044 14.0 0.0 0.15 12.2 0.0 2.1 1 0 0 1 1 1 0 Thioredoxin-like Imm27 PF15590.6 ORY48571.1 - 0.12 12.1 0.3 0.35 10.7 0.3 1.8 1 0 0 1 1 1 0 Immunity protein 27 XRN_N PF03159.18 ORY48574.1 - 6.5e-21 74.9 0.0 1.7e-17 63.7 0.0 2.8 2 1 0 2 2 2 2 XRN 5'-3' exonuclease N-terminus Cyclin_N PF00134.23 ORY48575.1 - 4e-07 29.8 0.9 5.9e-07 29.3 0.9 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORY48575.1 - 1.8e-05 25.1 0.5 2.6e-05 24.6 0.5 1.2 1 0 0 1 1 1 1 Cyclin DUF4834 PF16118.5 ORY48576.1 - 0.5 11.4 3.4 0.54 11.3 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TFIIB PF00382.19 ORY48580.1 - 6.2e-33 112.7 1.0 1.3e-19 70.0 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 ORY48580.1 - 2.3e-07 30.2 2.2 7.5e-07 28.6 2.2 1.9 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 ORY48580.1 - 5.1e-05 23.0 0.1 0.039 13.7 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Pox_Ag35 PF03286.14 ORY48580.1 - 0.013 15.3 9.0 0.02 14.7 9.0 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF1168 PF06658.12 ORY48580.1 - 0.15 11.9 12.4 0.27 11.1 12.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) AP3D1 PF06375.11 ORY48580.1 - 0.35 11.1 10.1 0.59 10.4 10.1 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF4337 PF14235.6 ORY48580.1 - 2.1 8.5 4.7 4 7.5 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) CRM1_repeat_3 PF18787.1 ORY48581.1 - 0.066 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 CRM1 / Exportin repeat 3 AAA_11 PF13086.6 ORY48582.1 - 1.2e-65 221.9 1.0 1.4e-65 221.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 ORY48582.1 - 1.9e-59 200.6 0.6 9.6e-59 198.3 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 ORY48582.1 - 5.2e-10 39.8 1.5 0.0029 18.0 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.6 ORY48582.1 - 2.7e-07 30.5 0.7 0.00042 20.1 0.5 2.9 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 ORY48582.1 - 2.9e-07 30.5 0.1 0.28 10.9 0.0 3.6 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 ORY48582.1 - 0.026 14.4 0.0 0.29 11.0 0.0 2.4 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain DEAD PF00270.29 ORY48582.1 - 0.041 13.6 0.3 0.25 11.1 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase UvrD-helicase PF00580.21 ORY48582.1 - 0.064 12.8 11.3 0.38 10.2 0.2 3.1 3 1 0 3 3 3 0 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 ORY48582.1 - 0.069 13.5 0.2 0.069 13.5 0.2 2.1 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 ORY48582.1 - 0.092 13.0 0.6 0.53 10.5 0.2 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ORY48582.1 - 0.19 12.1 2.5 0.22 12.0 0.6 2.1 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 ORY48582.1 - 0.36 10.1 2.4 0.37 10.1 0.0 2.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family HJURP_mid PF12346.8 ORY48582.1 - 1.1 9.7 4.6 0.52 10.8 0.3 2.2 2 0 0 2 2 2 0 Holliday junction recognition protein-associated repeat AAA_23 PF13476.6 ORY48582.1 - 4.4 7.8 11.2 0.15 12.6 0.7 2.8 3 0 0 3 3 3 0 AAA domain Gti1_Pac2 PF09729.9 ORY48583.1 - 5.4e-28 98.3 0.3 4.8e-23 82.2 0.0 2.6 2 1 1 3 3 3 2 Gti1/Pac2 family YbbR PF07949.12 ORY48583.1 - 0.15 12.5 0.0 0.42 11.0 0.0 1.7 2 0 0 2 2 2 0 YbbR-like protein IBN_N PF03810.19 ORY48584.1 - 1.3e-10 41.0 0.0 9.3e-10 38.3 0.0 2.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 ORY48584.1 - 2e-09 36.8 0.6 5.2e-09 35.4 0.6 1.7 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 ORY48584.1 - 0.0067 15.0 1.0 0.018 13.5 1.0 1.7 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus TAF6_C PF07571.13 ORY48584.1 - 0.044 14.1 0.0 2 8.8 0.0 3.6 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain zf-MYND PF01753.18 ORY48585.1 - 5.8e-10 39.1 14.5 5.8e-10 39.1 14.5 2.5 3 0 0 3 3 3 1 MYND finger zf-C6H2 PF15801.5 ORY48585.1 - 1.2 9.5 10.2 2.7 8.4 10.2 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 ORY48585.1 - 2.4 8.1 13.6 0.37 10.7 9.4 2.0 2 0 0 2 2 2 0 HIT zinc finger Glyco_hydro_63 PF03200.16 ORY48586.1 - 3.2e-166 553.9 3.9 9e-165 549.1 3.9 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 ORY48586.1 - 5.4e-50 170.6 0.0 1e-49 169.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 ORY48586.1 - 0.0012 17.8 0.1 0.0018 17.2 0.1 1.2 1 0 0 1 1 1 1 Trehalase Exostosin PF03016.15 ORY48587.1 - 1.9e-36 125.8 0.7 4.7e-34 118.0 0.7 2.1 1 1 0 1 1 1 1 Exostosin family Erf4 PF10256.9 ORY48588.1 - 0.03 14.4 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Enkurin PF13864.6 ORY48589.1 - 0.13 12.7 5.4 0.26 11.8 5.4 1.5 1 0 0 1 1 1 0 Calmodulin-binding Atg14 PF10186.9 ORY48589.1 - 0.19 10.8 3.8 0.3 10.2 3.8 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4162 PF13732.6 ORY48589.1 - 0.69 10.7 3.8 1.2 9.9 0.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4162) Flu_NS1 PF00600.19 ORY48590.1 - 0.024 14.2 0.1 0.029 13.9 0.1 1.2 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) DUF4191 PF13829.6 ORY48590.1 - 0.1 11.9 0.2 0.15 11.4 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) GIT_CC PF16559.5 ORY48590.1 - 0.94 9.4 8.4 2.4 8.1 5.1 2.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor LMBR1 PF04791.16 ORY48590.1 - 2.3 7.0 3.5 2.5 6.9 3.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DivIC PF04977.15 ORY48590.1 - 4.2 7.2 9.4 0.66 9.8 4.5 1.9 2 0 0 2 2 2 0 Septum formation initiator HEAT PF02985.22 ORY48591.1 - 0.0035 17.5 1.3 67 4.1 0.0 6.3 8 0 0 8 8 8 1 HEAT repeat Cnd1 PF12717.7 ORY48591.1 - 0.11 12.5 2.7 15 5.6 0.1 4.5 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Glyco_transf_90 PF05686.12 ORY48592.1 - 1.8e-23 83.1 3.0 5.6e-23 81.5 3.0 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 90 Glycos_transf_1 PF00534.20 ORY48593.1 - 1.8e-08 34.1 0.0 5.1e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY48593.1 - 3.2e-06 27.6 0.0 6.9e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3336 PF11815.8 ORY48594.1 - 7.1e-32 110.0 4.3 2.3e-31 108.4 2.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 ORY48594.1 - 2.2e-12 47.6 0.0 4e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Op_neuropeptide PF08035.11 ORY48594.1 - 0.13 12.2 0.1 0.43 10.5 0.1 1.9 1 0 0 1 1 1 0 Opioids neuropeptide Porin_3 PF01459.22 ORY48595.1 - 8.1e-53 179.6 8.5 9.1e-53 179.4 8.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin OMP_b-brl PF13505.6 ORY48595.1 - 0.094 12.8 6.4 0.049 13.8 2.4 2.2 2 0 0 2 2 2 0 Outer membrane protein beta-barrel domain Abhydrolase_6 PF12697.7 ORY48596.1 - 1e-23 85.1 1.0 1.3e-23 84.8 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY48596.1 - 4.8e-12 45.6 0.4 7.8e-12 45.0 0.4 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY48596.1 - 1.8e-09 37.6 0.6 6.4e-09 35.8 0.6 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 ORY48596.1 - 0.0012 18.6 0.1 0.0022 17.7 0.1 1.4 1 0 0 1 1 1 1 Putative esterase DUF900 PF05990.12 ORY48596.1 - 0.0019 17.8 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 ORY48596.1 - 0.0022 17.7 1.1 0.0082 15.9 0.4 2.0 1 1 1 2 2 2 1 PGAP1-like protein Chlorophyllase2 PF12740.7 ORY48596.1 - 0.0043 16.0 0.1 0.0076 15.2 0.1 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.20 ORY48596.1 - 0.0099 16.0 0.0 0.069 13.3 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain Ser_hydrolase PF06821.13 ORY48596.1 - 0.011 15.6 3.2 0.013 15.4 0.1 2.2 2 0 0 2 2 2 0 Serine hydrolase Lipase_3 PF01764.25 ORY48596.1 - 0.022 14.6 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.15 ORY48596.1 - 0.027 13.6 0.1 0.055 12.6 0.0 1.4 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Pribosyltran PF00156.27 ORY48596.1 - 0.044 13.3 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase domain Imm65 PF15582.6 ORY48596.1 - 0.061 12.2 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 65 VirJ PF06057.11 ORY48596.1 - 0.067 13.1 0.1 0.17 11.8 0.0 1.6 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) DUF2974 PF11187.8 ORY48596.1 - 0.15 11.6 0.0 0.37 10.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) DLH PF01738.18 ORY48596.1 - 0.15 11.6 0.1 1 8.8 0.1 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family PAF-AH_p_II PF03403.13 ORY48596.1 - 0.25 9.8 2.2 7.5 4.9 0.1 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II DUF4558 PF15104.6 ORY48597.1 - 2e-12 47.0 3.6 2e-12 47.0 3.6 2.1 1 1 0 2 2 2 1 Domain of unknown function (DUF4558) cNMP_binding PF00027.29 ORY48597.1 - 2.7e-12 46.6 0.0 1.3e-11 44.4 0.0 2.2 3 0 0 3 3 3 1 Cyclic nucleotide-binding domain DAO PF01266.24 ORY48600.1 - 1.1e-49 169.9 0.1 1.6e-49 169.4 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 ORY48600.1 - 1.1e-46 157.7 0.2 2.1e-46 156.9 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 ORY48600.1 - 1.8e-07 30.6 2.7 4.6e-05 22.7 0.4 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 ORY48600.1 - 2.4e-06 27.2 0.4 2.4e-06 27.2 0.4 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 ORY48600.1 - 0.0004 19.7 0.1 0.00096 18.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY48600.1 - 0.0033 16.2 0.5 0.0091 14.7 0.4 1.7 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 ORY48600.1 - 0.006 15.7 0.8 0.06 12.4 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 ORY48600.1 - 0.0099 15.1 0.1 0.027 13.7 0.1 1.7 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 ORY48600.1 - 0.01 15.1 0.0 1.8 7.7 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 ORY48600.1 - 0.022 14.0 0.2 0.067 12.4 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY48600.1 - 0.024 14.9 1.3 0.069 13.4 0.7 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY48600.1 - 0.063 13.8 0.1 0.22 12.1 0.1 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Gti1_Pac2 PF09729.9 ORY48601.1 - 4.3e-29 101.9 0.5 2.9e-24 86.1 0.0 2.8 2 1 1 3 3 3 2 Gti1/Pac2 family Importin_rep PF18773.1 ORY48602.1 - 1.9e-07 30.6 0.6 5.5e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 Importin 13 repeat E3_UbLigase_R4 PF13764.6 ORY48602.1 - 0.13 10.4 0.0 4 5.5 0.0 2.1 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase UBR4 CRM1_C PF08767.11 ORY48602.1 - 0.17 11.0 0.0 15 4.6 0.0 2.2 2 0 0 2 2 2 0 CRM1 C terminal 7tm_3 PF00003.22 ORY48603.1 - 1.8e-17 63.9 19.2 2.8e-17 63.2 19.2 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 ORY48604.1 - 9.4e-13 48.0 0.1 1.3e-12 47.5 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY48604.1 - 0.0037 17.0 0.0 0.0054 16.4 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein ABC_sub_bind PF04392.12 ORY48604.1 - 0.13 11.5 0.0 0.64 9.2 0.0 1.8 2 0 0 2 2 2 0 ABC transporter substrate binding protein Usp PF00582.26 ORY48605.1 - 8.5e-11 42.5 0.0 9.2e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family FerI PF08151.12 ORY48605.1 - 0.082 13.0 0.0 0.29 11.3 0.0 1.8 2 0 0 2 2 2 0 FerI (NUC094) domain FrpC PF06901.12 ORY48605.1 - 0.24 11.0 0.0 0.29 10.7 0.0 1.1 1 0 0 1 1 1 0 RTX iron-regulated protein FrpC Ada3 PF10198.9 ORY48607.1 - 1.3e-24 86.8 1.2 2.4e-24 85.9 1.2 1.4 1 1 0 1 1 1 1 Histone acetyltransferases subunit 3 Sec10 PF07393.11 ORY48607.1 - 0.036 12.5 0.0 0.046 12.2 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 DUF3810 PF12725.7 ORY48607.1 - 0.14 11.5 0.5 0.2 11.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF1168 PF06658.12 ORY48608.1 - 1.1e-39 135.3 22.0 1.3e-39 135.2 22.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) NARP1 PF12569.8 ORY48608.1 - 2.1 7.2 17.4 2.5 6.9 17.4 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2201_N PF13203.6 ORY48608.1 - 5.3 6.6 11.4 5.4 6.5 11.4 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Gti1_Pac2 PF09729.9 ORY48608.1 - 5.5 7.0 10.6 8.9 6.4 10.6 1.4 1 1 0 1 1 1 0 Gti1/Pac2 family DUF1202 PF06717.11 ORY48610.1 - 0.011 15.2 0.6 0.015 14.7 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) RAI1 PF08652.11 ORY48610.1 - 0.036 14.3 0.3 0.096 12.9 0.3 1.7 1 0 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease Nup54 PF13874.6 ORY48610.1 - 0.05 13.7 1.2 0.48 10.5 0.1 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Csm2_III-A PF03750.13 ORY48610.1 - 0.4 11.5 5.0 8 7.3 0.3 2.6 2 0 0 2 2 2 0 Csm2 Type III-A DUF4763 PF15960.5 ORY48610.1 - 6.9 5.9 11.0 15 4.8 4.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4763) Telomere_reg-2 PF10193.9 ORY48611.1 - 7.1e-18 65.1 0.3 2.4e-17 63.4 0.3 1.9 1 0 0 1 1 1 1 Telomere length regulation protein Calcipressin PF04847.12 ORY48611.1 - 0.097 12.4 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Calcipressin Usp PF00582.26 ORY48612.1 - 4.4e-25 88.8 0.0 1.4e-24 87.2 0.0 1.7 1 1 0 1 1 1 1 Universal stress protein family Usp PF00582.26 ORY48613.1 - 2.8e-26 92.7 0.0 3.9e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Taxilin PF09728.9 ORY48614.1 - 9.3e-65 218.8 46.5 2.9e-64 217.2 46.5 1.8 1 1 0 1 1 1 1 Myosin-like coiled-coil protein DUF2550 PF10739.9 ORY48614.1 - 0.13 12.2 0.2 0.4 10.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2550) DUF3574 PF12098.8 ORY48614.1 - 0.9 9.4 5.0 0.36 10.7 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) ERM PF00769.19 ORY48614.1 - 4.3 7.1 53.4 0.075 12.8 7.2 3.0 2 1 0 2 2 2 0 Ezrin/radixin/moesin family Abhydrolase_3 PF07859.13 ORY48615.1 - 3.2e-43 148.0 0.0 5.9e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY48615.1 - 2.2e-16 59.7 0.0 3.2e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 ORY48615.1 - 0.018 13.9 0.0 1.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Carboxylesterase family AXE1 PF05448.12 ORY48615.1 - 0.12 11.1 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 ORY48616.1 - 1.6e-39 136.0 0.2 4.9e-39 134.4 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY48616.1 - 3.8e-15 55.6 0.0 5.6e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 ORY48616.1 - 0.0026 16.7 0.2 0.14 11.0 0.0 2.7 2 1 1 3 3 3 1 Carboxylesterase family Mdv1 PF11542.8 ORY48616.1 - 0.0086 16.0 1.0 0.021 14.8 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial division protein 1 DUF1561 PF07598.11 ORY48616.1 - 0.019 13.2 0.1 0.055 11.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1561) AXE1 PF05448.12 ORY48616.1 - 0.11 11.1 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) MFA1_2 PF17317.2 ORY48616.1 - 0.65 9.8 3.0 13 5.6 0.0 2.6 2 0 0 2 2 2 0 Mating hormone A-factor 1&2 Prenyltrans PF00432.21 ORY48617.1 - 1.4e-36 123.9 9.8 5.9e-09 35.5 0.0 5.6 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 ORY48617.1 - 0.00093 18.4 0.0 0.047 12.8 0.0 2.1 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 ORY48617.1 - 0.001 18.3 0.0 0.66 9.0 0.0 2.5 1 1 1 2 2 2 2 Squalene-hopene cyclase N-terminal domain SPX PF03105.19 ORY48618.1 - 9.2 6.1 37.5 12 5.6 37.5 1.2 1 0 0 1 1 1 0 SPX domain zf-RRN7 PF11781.8 ORY48619.1 - 0.0045 16.6 1.3 0.016 14.9 1.3 1.9 1 1 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 CBM_3 PF00942.18 ORY48621.1 - 0.14 12.6 0.1 0.18 12.2 0.1 1.2 1 0 0 1 1 1 0 Cellulose binding domain NOB1_Zn_bind PF08772.11 ORY48622.1 - 1.1e-32 111.9 2.6 2e-32 111.2 2.6 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 ORY48622.1 - 3.3e-26 91.6 0.9 3.3e-26 91.6 0.9 2.1 2 0 0 2 2 2 1 PIN domain of ribonuclease S_100 PF01023.19 ORY48622.1 - 0.077 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Rhodanese_C PF12368.8 ORY48622.1 - 0.14 12.6 0.5 0.25 11.8 0.5 1.3 1 0 0 1 1 1 0 Rhodanase C-terminal WRNPLPNID PF15017.6 ORY48622.1 - 1.9 9.4 5.0 1.2 10.1 2.1 2.1 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box MSP1_C PF07462.11 ORY48622.1 - 2.5 6.7 7.0 4.2 5.9 7.0 1.4 1 1 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PRCC PF10253.9 ORY48622.1 - 8.3 7.1 13.4 14 6.4 13.4 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Pkinase PF00069.25 ORY48623.1 - 9e-68 228.5 0.0 1.1e-67 228.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY48623.1 - 1.9e-53 181.4 0.0 2.4e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY48623.1 - 0.0028 16.5 0.0 0.0043 15.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY48623.1 - 0.0095 14.9 0.1 0.55 9.1 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 ORY48623.1 - 0.013 14.8 0.0 0.076 12.3 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Ctr PF04145.15 ORY48624.1 - 1.2e-32 113.6 2.6 1.7e-32 113.1 2.6 1.2 1 0 0 1 1 1 1 Ctr copper transporter family UL41A PF17591.2 ORY48626.1 - 7.6 6.7 10.2 1.1 9.5 1.6 2.8 1 1 2 3 3 3 0 Herpesvirus UL41A PNK3P PF08645.11 ORY48627.1 - 1.3e-45 155.1 0.0 1.8e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 ORY48627.1 - 1.6e-16 60.7 0.0 6.9e-07 29.5 0.0 2.4 1 1 1 2 2 2 2 AAA domain KTI12 PF08433.10 ORY48627.1 - 3.5e-05 23.4 1.8 0.0089 15.5 0.1 2.2 1 1 1 2 2 2 2 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 ORY48627.1 - 0.00015 21.1 0.0 0.0003 20.1 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin HAD PF12710.7 ORY48627.1 - 0.087 13.2 0.7 0.5 10.8 0.5 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase AAA_16 PF13191.6 ORY48627.1 - 0.14 12.5 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain LSM PF01423.22 ORY48628.1 - 3.5e-15 55.4 0.0 3.8e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORY48628.1 - 9.1e-05 22.5 0.0 9.8e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 ORY48628.1 - 0.016 15.3 0.0 0.017 15.2 0.0 1.1 1 0 0 1 1 1 0 Scd6-like Sm domain UBX PF00789.20 ORY48629.1 - 3.5e-15 56.0 0.5 9.9e-15 54.5 0.5 1.8 2 0 0 2 2 2 1 UBX domain Thioredoxin_7 PF13899.6 ORY48629.1 - 6e-12 45.6 0.0 1.4e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.6 ORY48629.1 - 6.3e-10 38.7 0.1 3.5e-09 36.3 0.1 2.2 2 0 0 2 2 2 1 UBA-like domain UIM PF02809.20 ORY48629.1 - 0.081 12.9 0.6 0.081 12.9 0.6 3.6 4 0 0 4 4 4 0 Ubiquitin interaction motif Thioredoxin_2 PF13098.6 ORY48629.1 - 0.088 13.3 0.0 1.1 9.7 0.0 2.7 1 1 1 2 2 2 0 Thioredoxin-like domain NOA36 PF06524.12 ORY48629.1 - 1.2 8.4 6.4 1.8 7.8 6.4 1.2 1 0 0 1 1 1 0 NOA36 protein OTCace PF00185.24 ORY48630.1 - 3.7e-38 131.1 0.1 6e-38 130.4 0.1 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 ORY48630.1 - 2e-29 102.5 0.0 3e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain KN_motif PF12075.8 ORY48630.1 - 0.2 11.5 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 KN motif Thr_synth_N PF14821.6 ORY48631.1 - 2e-22 79.2 0.0 4.4e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.25 ORY48631.1 - 0.00019 21.0 0.0 0.00027 20.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Mito_carr PF00153.27 ORY48632.1 - 4.3e-59 196.5 6.7 1.1e-21 76.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY48632.1 - 0.54 9.4 4.8 4 6.5 0.1 3.0 1 1 3 4 4 4 0 Gammaproteobacterial serine protease PTS_2-RNA PF01885.16 ORY48633.1 - 8.8e-67 224.6 0.0 1e-66 224.5 0.0 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family HgmA PF04209.13 ORY48633.1 - 0.086 11.5 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 homogentisate 1,2-dioxygenase Imm-NTF2 PF15655.6 ORY48633.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 NTF2 fold immunity protein Rac1 PF09632.10 ORY48633.1 - 0.17 11.1 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 Rac1-binding domain FKBP_C PF00254.28 ORY48634.1 - 7.9e-06 26.1 0.0 1.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_C PF00254.28 ORY48635.1 - 1e-22 80.2 0.0 3.1e-21 75.5 0.0 2.1 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_C PF00254.28 ORY48636.1 - 3.7e-53 177.8 0.0 2.4e-30 104.7 0.0 2.2 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_C PF00254.28 ORY48637.1 - 2.7e-11 43.6 0.0 8.8e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase Peptidase_S10 PF00450.22 ORY48638.1 - 5e-80 269.9 0.4 6.7e-80 269.5 0.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF3732 PF12532.8 ORY48638.1 - 0.17 11.5 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3732) FATC PF02260.20 ORY48639.1 - 0.039 13.8 0.8 0.18 11.7 0.0 2.5 3 0 0 3 3 3 0 FATC domain DASH_Spc19 PF08287.11 ORY48639.1 - 0.7 9.8 6.5 2.3 8.1 6.5 1.8 2 0 0 2 2 2 0 Spc19 UL42 PF17638.2 ORY48639.1 - 1 9.3 4.9 1 9.3 2.7 2.1 2 0 0 2 2 2 0 HCMV UL42 Peptidase_S10 PF00450.22 ORY48641.1 - 1.6e-41 143.1 0.0 1.7e-41 143.0 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase PDZ_1 PF12812.7 ORY48643.1 - 9.1e-30 102.5 0.0 6.3e-21 74.2 0.0 2.9 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.6 ORY48643.1 - 7.6e-23 80.7 0.1 3e-07 30.6 0.0 4.7 4 0 0 4 4 4 3 PDZ domain PDZ_6 PF17820.1 ORY48643.1 - 1.6e-21 75.9 0.1 4.7e-08 32.7 0.0 4.7 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.6 ORY48643.1 - 4.7e-16 60.0 0.0 2.7e-15 57.6 0.0 2.1 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ PF00595.24 ORY48643.1 - 9e-12 45.2 0.0 9.2e-05 22.7 0.0 4.1 3 0 0 3 3 3 2 PDZ domain Tricorn_PDZ PF14685.6 ORY48643.1 - 9.1e-06 25.6 0.8 0.29 11.1 0.0 3.4 3 0 0 3 3 3 2 Tricorn protease PDZ domain PDZ_3 PF17815.1 ORY48643.1 - 0.00095 19.0 0.1 0.77 9.6 0.0 3.7 3 1 0 3 3 3 1 PDZ domain Peptidase_S46 PF10459.9 ORY48643.1 - 0.027 13.1 0.2 0.041 12.5 0.2 1.1 1 0 0 1 1 1 0 Peptidase S46 Peptidase_S7 PF00949.21 ORY48643.1 - 0.1 12.4 0.7 0.23 11.3 0.7 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.16 ORY48643.1 - 0.32 10.5 0.3 0.46 10.0 0.3 1.1 1 0 0 1 1 1 0 Putative peptidase (DUF31) Hexapep PF00132.24 ORY48646.1 - 2.1e-07 30.4 1.6 4.8e-06 26.1 0.4 2.7 1 1 2 3 3 3 1 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 ORY48646.1 - 0.0017 18.1 1.0 0.0017 18.1 1.0 2.4 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase ERG4_ERG24 PF01222.17 ORY48647.1 - 1.2e-118 396.6 2.8 1.8e-118 396.1 2.8 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 ORY48647.1 - 0.0035 16.9 1.2 0.0056 16.2 0.3 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Pkinase PF00069.25 ORY48648.1 - 2.1e-26 92.9 0.0 1.7e-16 60.4 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY48648.1 - 2e-08 33.8 0.0 3e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY48648.1 - 0.25 10.3 0.3 0.38 9.7 0.3 1.2 1 0 0 1 1 1 0 Haspin like kinase domain ubiquitin PF00240.23 ORY48650.1 - 7e-11 41.7 0.0 1.6e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 ORY48650.1 - 2.3e-05 24.2 0.0 4.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PRIMA1 PF16101.5 ORY48650.1 - 0.013 15.5 8.2 0.013 15.5 8.2 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 NeA_P2 PF12312.8 ORY48650.1 - 0.077 12.4 1.4 0.16 11.4 1.4 1.4 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein Ubiquitin_4 PF18036.1 ORY48650.1 - 0.2 11.7 0.1 3.2 7.9 0.0 2.6 2 1 1 3 3 3 0 Ubiquitin-like domain CAP_N PF01213.19 ORY48650.1 - 2 7.8 5.7 5.4 6.4 5.7 1.7 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal EF-hand_1 PF00036.32 ORY48655.1 - 3.3e-28 95.1 3.9 1.1e-05 24.6 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORY48655.1 - 5.1e-26 90.9 3.4 3.4e-12 46.6 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY48655.1 - 3.6e-23 79.5 2.8 5.7e-05 22.7 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 ORY48655.1 - 1.1e-20 72.1 2.5 0.00035 19.9 0.0 5.0 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 ORY48655.1 - 1e-18 66.9 3.2 2.4e-05 24.1 0.2 4.3 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_11 PF08976.11 ORY48655.1 - 0.0028 18.5 0.1 0.039 14.8 0.0 2.2 1 1 1 2 2 2 1 EF-hand domain EF-hand_9 PF14658.6 ORY48655.1 - 0.013 15.8 0.0 2 8.8 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain Dockerin_1 PF00404.18 ORY48655.1 - 0.02 15.1 0.5 15 5.9 0.1 3.1 2 1 1 3 3 3 0 Dockerin type I domain EF-hand_10 PF14788.6 ORY48655.1 - 0.03 14.2 0.9 4.7 7.2 0.1 3.0 3 0 0 3 3 3 0 EF hand DUF5580 PF17743.1 ORY48655.1 - 0.051 12.1 0.0 0.32 9.5 0.0 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5580) SPARC_Ca_bdg PF10591.9 ORY48655.1 - 0.054 13.8 1.0 1.6 9.0 0.2 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 ORY48655.1 - 0.23 11.4 3.6 10 6.1 0.1 3.3 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand Colicin_immun PF09204.10 ORY48655.1 - 0.47 11.0 3.6 11 6.6 0.6 2.7 2 1 1 3 3 3 0 Bacterial self-protective colicin-like immunity tRNA-synt_1g PF09334.11 ORY48656.1 - 2.8e-59 200.8 0.0 5.8e-29 101.0 0.0 3.1 1 1 2 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ORY48656.1 - 1e-17 63.6 0.3 4.4e-09 35.1 0.0 2.3 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 ORY48656.1 - 5.5e-06 25.9 0.0 0.0048 16.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 ORY48656.1 - 0.0032 16.4 0.0 0.0063 15.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (K) tRNA-synt_1d PF00750.19 ORY48656.1 - 0.015 14.3 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (R) Anticodon_1 PF08264.13 ORY48656.1 - 0.022 14.7 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA ANAPC4_WD40 PF12894.7 ORY48658.1 - 1.1e-07 32.1 0.2 0.11 12.7 0.1 3.6 2 1 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY48658.1 - 6e-06 26.9 0.6 0.0026 18.6 0.5 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 ORY48658.1 - 0.015 14.2 0.0 0.04 12.9 0.0 1.7 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Mito_carr PF00153.27 ORY48659.1 - 8.3e-19 67.3 5.8 2.6e-08 33.6 0.5 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein PP2 PF14299.6 ORY48660.1 - 1.9e-09 37.7 0.0 2.9e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Phloem protein 2 F-box-like PF12937.7 ORY48660.1 - 3.7e-05 23.5 2.0 5.6e-05 22.9 0.3 2.1 2 0 0 2 2 2 1 F-box-like Pkinase PF00069.25 ORY48661.1 - 3.8e-51 174.0 0.0 2e-37 129.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY48661.1 - 3.3e-25 88.9 0.0 3.9e-17 62.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY48661.1 - 4e-08 32.9 0.0 5.8e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY48661.1 - 7.7e-06 25.4 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY48661.1 - 0.0013 18.8 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY48661.1 - 0.013 14.4 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 ORY48661.1 - 0.023 13.5 0.0 0.05 12.4 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 ORY48661.1 - 0.026 14.2 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 ORY48661.1 - 0.038 13.6 0.0 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family MF_alpha_N PF05436.11 ORY48662.1 - 0.14 12.1 0.7 0.35 10.8 0.7 1.9 1 1 0 1 1 1 0 Mating factor alpha precursor N-terminus CRAL_TRIO PF00650.20 ORY48664.1 - 2.3e-35 121.7 0.1 3.2e-35 121.2 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORY48664.1 - 0.00047 20.3 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Baculo_RING PF05883.11 ORY48664.1 - 0.056 13.4 0.0 0.096 12.7 0.0 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain THB PF18362.1 ORY48664.1 - 0.28 10.8 2.2 0.29 10.8 0.4 2.0 2 0 0 2 2 2 0 Tri-helix bundle domain BUD22 PF09073.10 ORY48665.1 - 0.0014 18.1 20.8 0.0017 17.8 20.8 1.0 1 0 0 1 1 1 1 BUD22 TFIIF_alpha PF05793.12 ORY48665.1 - 0.051 12.2 20.5 0.07 11.7 20.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TFIIA PF03153.13 ORY48665.1 - 0.076 13.0 13.7 0.087 12.8 13.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MIF4G_like_2 PF09090.11 ORY48665.1 - 0.51 9.8 7.4 0.71 9.3 7.4 1.1 1 0 0 1 1 1 0 MIF4G like PAPA-1 PF04795.12 ORY48665.1 - 0.54 11.1 13.6 0.17 12.7 0.9 2.6 3 0 0 3 3 3 0 PAPA-1-like conserved region CENP-B_dimeris PF09026.10 ORY48665.1 - 1 9.8 23.5 1.1 9.7 11.8 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Ebp2 PF05890.12 ORY48666.1 - 2.6e-51 174.7 9.0 2.9e-51 174.6 9.0 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Peptidase_M28 PF04389.17 ORY48667.1 - 9e-35 120.2 0.2 1.4e-34 119.5 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 ORY48667.1 - 0.078 12.7 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 PPR PF01535.20 ORY48670.1 - 3.5e-22 77.0 9.8 0.00035 20.6 0.1 5.6 5 0 0 5 5 5 4 PPR repeat PPR_2 PF13041.6 ORY48670.1 - 3.7e-18 65.4 6.6 3.1e-07 30.5 0.3 5.3 3 1 2 5 5 5 4 PPR repeat family PPR_1 PF12854.7 ORY48670.1 - 1.1e-13 50.6 0.0 0.00014 21.5 0.0 5.0 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.6 ORY48670.1 - 2e-12 47.0 0.1 0.00051 20.1 0.0 4.9 4 1 2 6 6 6 4 Pentatricopeptide repeat domain PPR_long PF17177.4 ORY48670.1 - 0.0026 17.2 0.0 0.77 9.1 0.0 2.4 2 1 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP SET PF00856.28 ORY48671.1 - 4.6e-05 23.9 0.0 5.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 SET domain Response_reg PF00072.24 ORY48672.1 - 5.6e-07 29.7 1.7 6.8e-07 29.5 0.5 1.8 2 0 0 2 2 2 1 Response regulator receiver domain Maf PF02545.14 ORY48672.1 - 0.0088 15.9 0.3 0.0088 15.9 0.3 1.7 2 0 0 2 2 2 1 Maf-like protein AA_permease_2 PF13520.6 ORY48673.1 - 7.4e-22 77.8 51.3 7.4e-22 77.8 51.3 1.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY48673.1 - 3.5e-12 45.7 48.2 6.4e-12 44.8 48.2 1.3 1 1 0 1 1 1 1 Amino acid permease GerA PF03323.13 ORY48674.1 - 1.4 7.3 5.1 3 6.2 5.1 1.5 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein PX PF00787.24 ORY48675.1 - 1.7e-11 44.1 0.3 2.2e-11 43.7 0.3 1.2 1 0 0 1 1 1 1 PX domain WD40 PF00400.32 ORY48676.1 - 1.6e-11 44.5 14.7 0.0077 17.1 0.0 7.7 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY48676.1 - 8e-10 38.9 1.0 0.073 13.4 0.0 5.6 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 ORY48676.1 - 0.006 16.5 0.7 1.8 8.6 0.2 2.6 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Clathrin PF00637.20 ORY48676.1 - 0.097 12.5 0.4 7.5 6.4 0.0 2.5 3 0 0 3 3 3 0 Region in Clathrin and VPS Cation_efflux PF01545.21 ORY48677.1 - 1.2e-30 106.8 26.2 2.8e-30 105.5 26.2 1.6 1 1 0 1 1 1 1 Cation efflux family Pilus_CpaD PF09476.10 ORY48677.1 - 0.13 12.0 0.4 0.67 9.7 0.2 2.0 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) Promethin PF16015.5 ORY48680.1 - 3.6 7.5 14.3 7.7 6.5 14.3 1.5 1 0 0 1 1 1 0 Promethin YCII PF03795.14 ORY48681.1 - 1.5e-06 28.6 0.0 1.6e-06 28.4 0.0 1.0 1 0 0 1 1 1 1 YCII-related domain Gemin7 PF11095.8 ORY48682.1 - 6.1e-18 64.5 0.0 7.5e-18 64.2 0.0 1.1 1 0 0 1 1 1 1 Gem-associated protein 7 (Gemin7) LRR_8 PF13855.6 ORY48683.1 - 1.3e-17 63.3 18.3 1.7e-08 34.1 0.9 3.8 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY48683.1 - 3.5e-12 46.3 22.3 7.9e-07 29.3 3.1 4.1 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY48683.1 - 1.4e-10 40.2 12.2 0.019 15.4 0.1 6.3 7 1 0 7 7 7 4 Leucine Rich Repeat LRR_6 PF13516.6 ORY48683.1 - 0.76 10.0 0.0 0.76 10.0 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich repeat DUF3149 PF11346.8 ORY48684.1 - 0.014 15.0 0.2 0.018 14.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Phage_holin_2_4 PF16082.5 ORY48684.1 - 0.038 13.7 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like LRR_4 PF12799.7 ORY48685.1 - 2.6e-14 53.1 26.3 2e-05 24.8 0.5 4.6 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY48685.1 - 9.7e-14 50.9 27.4 4.8e-09 35.8 8.0 3.8 2 2 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 ORY48685.1 - 5.3e-07 29.3 23.1 1.3 9.9 1.0 7.7 6 2 0 6 6 6 4 Leucine Rich Repeat LRR_6 PF13516.6 ORY48685.1 - 0.0027 17.6 23.1 0.26 11.4 1.0 6.4 6 0 0 6 6 6 2 Leucine Rich repeat MAP2_projctn PF08377.10 ORY48685.1 - 0.24 9.4 0.1 0.32 9.0 0.1 1.0 1 0 0 1 1 1 0 MAP2/Tau projection domain ANAPC10 PF03256.16 ORY48687.1 - 2.4e-56 190.3 0.0 2.9e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 ORY48687.1 - 2.7e-07 30.7 0.0 3.6e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 F5/8 type C domain GST_C PF00043.25 ORY48688.1 - 5.3e-07 29.8 0.1 8.6e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY48688.1 - 5.6e-07 29.7 0.2 1.4e-06 28.4 0.2 1.6 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY48688.1 - 0.00058 19.8 0.0 0.00091 19.2 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY48688.1 - 0.0015 18.8 0.0 0.0037 17.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY48688.1 - 0.058 13.8 0.0 0.18 12.2 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Cation_efflux PF01545.21 ORY48689.1 - 7.1e-49 166.2 15.5 7.1e-49 166.2 15.5 1.6 2 1 0 2 2 2 1 Cation efflux family zf-C2H2 PF00096.26 ORY48690.1 - 0.0068 16.8 1.4 0.0068 16.8 1.4 3.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 ORY48690.1 - 0.019 14.9 4.0 0.061 13.2 4.0 2.0 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Zf_RING PF16744.5 ORY48690.1 - 0.043 13.9 1.4 0.2 11.8 0.1 2.4 2 0 0 2 2 2 0 KIAA1045 RING finger zf-C2H2_4 PF13894.6 ORY48690.1 - 0.15 13.0 7.2 0.26 12.2 3.6 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORY48690.1 - 4 7.3 7.7 0.6 9.9 2.1 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF2237 PF09996.9 ORY48692.1 - 9.1e-47 157.8 0.0 1.2e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) DUF2237 PF09996.9 ORY48693.1 - 1.8e-35 121.4 0.0 2.1e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) Cation_efflux PF01545.21 ORY48694.1 - 6.6e-44 150.0 20.9 1.8e-43 148.6 20.9 1.7 1 1 0 1 1 1 1 Cation efflux family Ank_2 PF12796.7 ORY48696.1 - 1.4e-27 96.1 0.3 7.1e-08 32.9 0.0 5.5 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY48696.1 - 3.7e-16 59.3 4.8 0.00038 21.0 0.0 7.0 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY48696.1 - 9.3e-16 57.7 7.2 0.044 14.1 0.0 9.8 5 4 6 12 12 12 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY48696.1 - 2.3e-15 55.2 11.5 2.3 9.1 0.0 11.2 11 0 0 11 11 11 4 Ankyrin repeat Ank PF00023.30 ORY48696.1 - 5.8e-10 39.2 6.7 0.29 11.6 0.0 9.1 9 1 1 10 10 10 1 Ankyrin repeat GAT PF03127.14 ORY48696.1 - 0.036 14.4 0.1 9.5 6.6 0.0 2.5 2 0 0 2 2 2 0 GAT domain Adaptin_N PF01602.20 ORY48698.1 - 5.4e-117 391.5 0.4 6.9e-117 391.2 0.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ORY48698.1 - 6.6e-13 49.0 3.3 9e-10 38.8 0.0 3.4 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORY48698.1 - 3.4e-07 29.9 5.4 3.2 8.2 0.0 6.6 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 ORY48698.1 - 1.4e-06 28.6 0.1 0.048 14.1 0.0 4.3 4 0 0 4 4 4 2 HEAT repeats TAF6_C PF07571.13 ORY48698.1 - 0.021 15.2 0.3 19 5.7 0.0 4.2 4 0 0 4 4 4 0 TAF6 C-terminal HEAT repeat domain PUF PF00806.19 ORY48698.1 - 0.069 12.9 0.3 0.32 10.8 0.0 2.4 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat Nucleotid_trans PF03407.16 ORY48699.1 - 1.9e-06 28.0 0.1 2.7e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase INSIG PF07281.12 ORY48700.1 - 1.3e-23 83.8 11.1 3.3e-20 72.6 2.2 2.6 1 1 1 2 2 2 2 Insulin-induced protein (INSIG) Dicty_CAR PF05462.11 ORY48702.1 - 0.045 12.9 1.0 0.056 12.6 1.0 1.1 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor Lectin_leg-like PF03388.13 ORY48703.1 - 2.7e-40 138.2 0.0 3.9e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 ORY48703.1 - 0.069 13.2 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial lectin Cadherin_C_2 PF16492.5 ORY48705.1 - 0.11 13.2 0.6 1.7 9.4 0.0 2.8 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal Thymidylate_kin PF02223.17 ORY48705.1 - 0.26 11.0 2.0 4.1 7.0 0.1 2.2 2 0 0 2 2 2 0 Thymidylate kinase Lectin_leg-like PF03388.13 ORY48706.1 - 1.8e-44 151.8 0.0 2.7e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.19 ORY48706.1 - 0.0031 17.1 0.0 0.013 15.1 0.0 2.0 1 1 0 1 1 1 1 Legume lectin domain DUF4407 PF14362.6 ORY48706.1 - 0.0055 16.1 0.0 0.0096 15.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Baculo_PEP_C PF04513.12 ORY48706.1 - 0.046 13.8 7.4 0.12 12.4 6.9 1.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_DNA_bd PF12329.8 ORY48706.1 - 0.05 13.6 0.7 0.05 13.6 0.7 2.4 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding LptD PF04453.14 ORY48706.1 - 0.098 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 LPS transport system D JTB PF05439.12 ORY48706.1 - 0.13 12.4 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 Jumping translocation breakpoint protein (JTB) CHDCT2 PF08074.11 ORY48706.1 - 0.23 11.6 1.3 0.38 10.9 1.3 1.3 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain DUF2312 PF10073.9 ORY48706.1 - 0.26 11.0 2.7 5.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) SlyX PF04102.12 ORY48706.1 - 0.42 11.3 0.0 0.42 11.3 0.0 3.3 4 0 0 4 4 4 0 SlyX Fib_alpha PF08702.10 ORY48706.1 - 0.7 10.1 10.1 0.095 12.9 6.0 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2408 PF10303.9 ORY48706.1 - 0.97 10.0 5.7 0.34 11.5 2.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Prominin PF05478.11 ORY48706.1 - 1.2 7.0 6.3 1.5 6.7 5.4 1.6 1 1 0 1 1 1 0 Prominin DUF1664 PF07889.12 ORY48706.1 - 7.6 6.6 11.4 0.32 11.0 1.0 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) XhlA PF10779.9 ORY48706.1 - 8.4 6.7 7.8 11 6.3 0.5 3.3 3 0 0 3 3 3 0 Haemolysin XhlA DUF1516 PF07457.11 ORY48707.1 - 0.047 13.9 1.3 0.082 13.1 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1516) DUF4040 PF13244.6 ORY48707.1 - 0.26 11.5 3.4 1.2 9.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4040) Otopetrin PF03189.13 ORY48708.1 - 0.00038 19.4 3.3 0.00038 19.4 3.3 1.4 2 0 0 2 2 2 1 Otopetrin GGACT PF06094.12 ORY48710.1 - 3.7e-11 43.7 0.2 8.7e-11 42.5 0.2 1.6 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like HTH_AsnC-type PF13404.6 ORY48710.1 - 0.0078 16.0 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 AsnC-type helix-turn-helix domain HTH_Tnp_ISL3 PF13542.6 ORY48710.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF746 PF05344.11 ORY48710.1 - 0.036 13.9 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) IF2_N PF04760.15 ORY48710.1 - 0.051 13.4 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region G_glu_transpept PF01019.21 ORY48711.1 - 2.2e-150 501.8 0.0 2.5e-150 501.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Homeobox_KN PF05920.11 ORY48712.1 - 1.3e-17 63.3 0.3 3.9e-17 61.9 0.3 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 ORY48712.1 - 2e-05 24.3 0.2 5.1e-05 23.0 0.2 1.7 1 0 0 1 1 1 1 Homeodomain CPSF_A PF03178.15 ORY48713.1 - 3.7e-50 171.1 0.1 2.3e-49 168.4 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 ORY48713.1 - 8.1e-30 103.9 0.9 3.7e-27 95.1 0.1 2.4 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term Peptidase_C14 PF00656.22 ORY48714.1 - 1.7e-36 126.5 0.0 3.4e-36 125.5 0.0 1.5 1 0 0 1 1 1 1 Caspase domain WW PF00397.26 ORY48714.1 - 1.4e-11 44.2 5.5 3e-11 43.2 5.5 1.6 1 0 0 1 1 1 1 WW domain Raptor_N PF14538.6 ORY48714.1 - 0.012 15.6 2.1 0.28 11.1 0.1 3.0 2 1 1 3 3 3 0 Raptor N-terminal CASPase like domain FliS_cochap PF16522.5 ORY48714.1 - 0.043 13.7 0.7 0.094 12.7 0.7 1.5 1 0 0 1 1 1 0 Flagellar FLiS export co-chaperone, HP1076 PAT1 PF09770.9 ORY48717.1 - 7.4 4.7 27.7 0.072 11.4 18.2 2.0 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 WD40 PF00400.32 ORY48718.1 - 5.9e-77 251.6 43.9 5.3e-08 33.4 0.1 11.2 11 0 0 11 11 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY48718.1 - 2e-24 85.7 15.3 0.001 19.4 0.1 8.7 1 1 8 9 9 9 7 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY48718.1 - 1.2e-23 83.6 21.3 8.4e-05 21.4 0.2 8.8 3 3 6 9 9 9 7 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY48718.1 - 1.7e-12 47.3 6.7 0.28 10.5 0.1 6.7 3 2 3 7 7 7 5 WD40-like domain Ge1_WD40 PF16529.5 ORY48718.1 - 3e-08 33.0 18.8 0.17 10.8 3.9 7.3 2 2 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORY48718.1 - 4.1e-07 28.9 6.9 0.057 12.0 0.0 4.6 2 1 2 5 5 5 3 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 ORY48718.1 - 2e-05 23.6 14.5 0.041 12.6 0.3 5.6 2 2 3 5 5 5 4 Nup133 N terminal like CDtoxinA PF03498.14 ORY48718.1 - 9.7e-05 22.0 3.7 1.1 8.9 0.0 4.6 3 1 2 5 5 5 2 Cytolethal distending toxin A/C domain TIR_2 PF13676.6 ORY48719.1 - 9.7e-14 52.0 0.0 2.6e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 TIR domain NACHT PF05729.12 ORY48719.1 - 8.1e-09 35.6 0.0 1.4e-07 31.6 0.0 3.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ORY48719.1 - 0.00024 21.5 0.0 0.0006 20.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain TIR PF01582.20 ORY48719.1 - 0.0013 18.6 0.0 0.0031 17.3 0.0 1.6 1 0 0 1 1 1 1 TIR domain AAA_19 PF13245.6 ORY48719.1 - 0.057 13.7 0.0 5.2 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 ORY48719.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) HSF_DNA-bind PF00447.17 ORY48720.1 - 3e-21 75.8 1.6 4.2e-21 75.4 0.0 2.1 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.24 ORY48720.1 - 1.6e-17 63.6 0.1 2.7e-13 50.0 0.1 2.6 2 0 0 2 2 2 2 Response regulator receiver domain PspA_IM30 PF04012.12 ORY48720.1 - 0.014 15.0 1.0 0.025 14.2 1.0 1.3 1 0 0 1 1 1 0 PspA/IM30 family Zwint PF15556.6 ORY48720.1 - 0.016 14.7 2.4 0.033 13.7 2.4 1.4 1 0 0 1 1 1 0 ZW10 interactor DUF1664 PF07889.12 ORY48720.1 - 0.043 13.8 2.1 0.12 12.4 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) TFIIA PF03153.13 ORY48720.1 - 0.067 13.2 19.9 0.12 12.4 19.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ZapB PF06005.12 ORY48720.1 - 0.078 13.4 2.4 0.16 12.4 2.4 1.5 1 0 0 1 1 1 0 Cell division protein ZapB Not3 PF04065.15 ORY48720.1 - 0.11 11.9 0.9 0.22 10.9 0.9 1.4 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component Laminin_II PF06009.12 ORY48720.1 - 0.2 11.7 3.9 0.58 10.2 3.5 1.9 2 0 0 2 2 2 0 Laminin Domain II CENP-F_leu_zip PF10473.9 ORY48720.1 - 0.21 11.6 4.0 0.42 10.6 4.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.11 ORY48720.1 - 0.4 11.0 2.2 1.8 8.9 2.2 2.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) ATG16 PF08614.11 ORY48720.1 - 0.54 10.5 9.2 3.1 8.0 5.4 2.6 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) SARAF PF06682.12 ORY48720.1 - 0.68 9.5 4.1 1.3 8.6 4.1 1.4 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis YabA PF06156.13 ORY48720.1 - 0.71 10.6 2.8 0.68 10.6 1.0 1.9 2 0 0 2 2 1 0 Initiation control protein YabA Phosphoesterase PF04185.14 ORY48721.1 - 0.03 13.5 0.1 0.03 13.5 0.1 1.2 1 0 0 1 1 1 0 Phosphoesterase family DegT_DnrJ_EryC1 PF01041.17 ORY48721.1 - 0.13 11.5 0.1 0.15 11.3 0.1 1.1 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family TelA PF05816.11 ORY48722.1 - 0.096 11.7 0.2 0.28 10.2 0.0 1.7 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) APG6_N PF17675.1 ORY48722.1 - 0.96 10.0 7.8 7.1 7.2 0.1 2.6 3 0 0 3 3 3 0 Apg6 coiled-coil region THOC7 PF05615.13 ORY48722.1 - 1.5 9.1 4.3 0.66 10.3 0.7 2.0 2 1 0 2 2 2 0 Tho complex subunit 7 HSF_DNA-bind PF00447.17 ORY48723.1 - 3.7e-18 65.9 0.1 4.2e-18 65.8 0.1 1.1 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 ORY48723.1 - 0.018 15.5 0.0 0.026 15.0 0.0 1.2 1 0 0 1 1 1 0 Ets-domain HSF_DNA-bind PF00447.17 ORY48724.1 - 6.4e-25 87.6 0.1 1.3e-24 86.6 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 ORY48724.1 - 0.11 13.0 0.1 0.5 10.9 0.0 2.2 2 0 0 2 2 2 0 Ets-domain Ins_allergen_rp PF06757.13 ORY48724.1 - 0.18 11.8 0.7 0.7 9.8 0.1 2.1 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification SYCE1 PF15233.6 ORY48725.1 - 0.017 15.2 8.2 0.043 13.9 8.2 1.6 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 Pkinase PF00069.25 ORY48727.1 - 3.8e-72 242.8 0.0 6.3e-72 242.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY48727.1 - 1.1e-44 152.7 0.0 1.6e-44 152.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 ORY48727.1 - 4.9e-16 58.3 0.1 1.2e-15 57.0 0.0 1.7 2 0 0 2 2 2 1 Kinase associated domain 1 Kinase-like PF14531.6 ORY48727.1 - 1.4e-05 24.6 0.0 3.6e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 ORY48727.1 - 0.00026 20.6 0.2 0.00049 19.8 0.2 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 ORY48727.1 - 0.0018 17.6 0.1 0.0032 16.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY48727.1 - 0.012 14.6 0.0 0.024 13.6 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 ORY48727.1 - 0.02 14.8 0.0 0.75 9.7 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Ank_2 PF12796.7 ORY48728.1 - 6.5e-34 116.4 2.4 4.5e-09 36.8 0.1 6.3 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY48728.1 - 1.2e-20 73.6 7.6 0.01 16.4 0.1 8.6 6 3 1 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY48728.1 - 5.8e-18 64.7 8.9 0.034 14.5 0.0 11.5 5 4 8 13 13 13 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY48728.1 - 3.1e-16 57.8 5.2 1.2 9.9 0.0 12.0 13 0 0 13 13 13 3 Ankyrin repeat Ank PF00023.30 ORY48728.1 - 3.7e-08 33.4 2.4 1.4 9.5 0.0 8.3 8 3 1 9 9 9 1 Ankyrin repeat DUF1036 PF06282.11 ORY48729.1 - 0.067 13.7 0.9 0.17 12.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1036) WSS_VP PF12175.8 ORY48729.1 - 0.14 11.6 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP Ank_4 PF13637.6 ORY48730.1 - 3.3e-24 84.9 0.3 5.5e-14 52.3 0.0 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY48730.1 - 4.6e-19 68.2 1.0 3.2e-11 43.2 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY48730.1 - 8.4e-18 64.7 0.1 1.5e-17 63.9 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) SH3_1 PF00018.28 ORY48730.1 - 2.8e-17 62.0 0.2 4.5e-17 61.4 0.2 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY48730.1 - 1.9e-16 59.6 0.1 2.9e-16 59.0 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain Ank_3 PF13606.6 ORY48730.1 - 4.1e-15 54.4 0.1 1.5e-06 28.1 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 ORY48730.1 - 2.2e-14 53.2 1.1 1.9e-05 24.9 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat SH3_2 PF07653.17 ORY48730.1 - 1.7e-12 46.8 0.0 2.9e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SnoaL_3 PF13474.6 ORY48730.1 - 0.2 11.9 0.0 27 5.1 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like domain Ribosomal_L22 PF00237.19 ORY48731.1 - 3.5e-20 72.2 1.4 8e-20 71.0 1.4 1.6 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e CKS PF01111.19 ORY48732.1 - 8.8e-34 115.6 0.7 1.2e-33 115.2 0.7 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit INSIG PF07281.12 ORY48733.1 - 0.0053 16.4 0.3 0.12 12.0 0.0 2.3 2 0 0 2 2 2 1 Insulin-induced protein (INSIG) Oxidored_q4 PF00507.19 ORY48733.1 - 0.0059 16.7 1.3 0.0059 16.7 1.3 2.5 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 PsaM PF07465.13 ORY48736.1 - 2.5 7.9 6.0 3.1 7.6 0.4 2.7 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) LRR_8 PF13855.6 ORY48737.1 - 8e-07 28.7 9.8 4.8e-05 23.0 6.2 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 ORY48737.1 - 2.4e-06 27.8 10.8 0.00051 20.4 0.6 2.7 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY48737.1 - 6.6e-05 22.9 12.2 0.46 11.2 0.1 5.3 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 ORY48737.1 - 0.18 11.9 10.6 2 8.7 0.1 3.8 4 0 0 4 4 4 0 Leucine Rich repeat Tom37 PF10568.9 ORY48738.1 - 3e-26 92.2 0.2 6.5e-26 91.1 0.1 1.6 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 ORY48738.1 - 8.2e-19 67.2 0.6 1.6e-18 66.2 0.6 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 ORY48738.1 - 3e-18 66.4 0.0 4.8e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 ORY48738.1 - 8.9e-06 25.6 0.0 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY48738.1 - 0.0018 18.5 0.0 0.0037 17.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain IBN_N PF03810.19 ORY48739.1 - 0.012 15.5 0.0 0.12 12.3 0.0 2.9 4 0 0 4 4 4 0 Importin-beta N-terminal domain Y_phosphatase2 PF03162.13 ORY48740.1 - 2.8e-59 199.4 0.1 4.3e-59 198.8 0.1 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 ORY48740.1 - 1.1e-07 32.1 0.0 1.6e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 ORY48740.1 - 0.0043 16.6 0.0 0.0057 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 ORY48740.1 - 0.0048 16.7 0.1 0.0078 16.0 0.1 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain HRG PF16954.5 ORY48741.1 - 0.0074 16.7 0.5 0.025 15.0 0.1 2.1 2 0 0 2 2 2 1 Haem-transporter, endosomal/lysosomal, haem-responsive gene LRR_4 PF12799.7 ORY48741.1 - 0.012 16.1 4.4 0.096 13.1 1.2 2.5 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.7 ORY48742.1 - 8.1e-08 32.5 24.1 0.0001 22.6 1.5 5.9 1 1 4 6 6 6 5 Leucine Rich repeats (2 copies) PTP_tm PF18861.1 ORY48742.1 - 0.021 14.8 0.2 0.042 13.8 0.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J LRR_1 PF00560.33 ORY48742.1 - 0.053 14.1 12.7 22 6.1 0.1 6.5 7 0 0 7 7 7 0 Leucine Rich Repeat Phage_Coat_B PF05356.11 ORY48742.1 - 0.082 12.8 0.2 0.18 11.7 0.2 1.6 1 0 0 1 1 1 0 Phage Coat protein B LRR_6 PF13516.6 ORY48742.1 - 0.18 11.9 14.3 8 6.8 0.0 6.5 7 0 0 7 7 7 0 Leucine Rich repeat FNIP PF05725.12 ORY48742.1 - 1.6 9.0 18.0 0.24 11.6 3.3 3.5 2 1 2 4 4 4 0 FNIP Repeat LRR_8 PF13855.6 ORY48742.1 - 2.1 8.1 21.4 3.3 7.5 3.0 5.6 2 1 2 5 5 5 0 Leucine rich repeat LRR_4 PF12799.7 ORY48743.1 - 4.7e-10 39.6 14.5 0.0048 17.3 0.7 5.4 2 2 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY48743.1 - 0.0002 21.1 4.8 5.9 7.2 0.1 5.5 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 ORY48743.1 - 0.00046 20.4 5.1 13 6.8 0.1 5.9 6 0 0 6 6 6 1 Leucine Rich Repeat PTP_tm PF18861.1 ORY48743.1 - 0.01 15.9 0.3 0.028 14.4 0.1 1.7 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J PIRT PF15099.6 ORY48743.1 - 0.03 13.9 0.0 0.066 12.8 0.0 1.5 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family LRR_8 PF13855.6 ORY48743.1 - 0.049 13.4 13.5 7.1 6.5 1.8 4.9 3 2 1 4 4 4 0 Leucine rich repeat ATP-grasp PF02222.22 ORY48744.1 - 1.6e-59 200.3 0.0 2.5e-59 199.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain AIRC PF00731.20 ORY48744.1 - 1.4e-36 125.3 0.5 1.1e-16 60.8 0.0 3.6 4 0 0 4 4 4 2 AIR carboxylase PurK_C PF17769.1 ORY48744.1 - 7.2e-17 60.8 0.0 1.5e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 ORY48744.1 - 1.6e-10 40.8 0.0 2.8e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 ORY48744.1 - 0.00049 19.7 0.0 0.0016 18.0 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus XdhC_C PF13478.6 ORY48744.1 - 0.055 14.0 0.3 0.58 10.7 0.0 2.5 2 1 1 3 3 3 0 XdhC Rossmann domain RimK PF08443.11 ORY48744.1 - 0.099 12.2 0.0 0.19 11.3 0.0 1.5 1 1 0 1 1 1 0 RimK-like ATP-grasp domain Ammonium_transp PF00909.21 ORY48745.1 - 4.3e-67 226.5 20.0 5.5e-37 127.4 10.9 3.0 2 1 1 3 3 3 3 Ammonium Transporter Family Cyt-b5 PF00173.28 ORY48746.1 - 7.9e-05 22.7 0.0 0.00022 21.3 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Condensation PF00668.20 ORY48747.1 - 3.5e-11 42.5 0.0 8.9e-09 34.5 0.0 2.7 2 1 0 2 2 2 2 Condensation domain CENP-F_leu_zip PF10473.9 ORY48747.1 - 2.6 8.0 13.4 0.041 13.9 1.8 3.1 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 C2 PF00168.30 ORY48838.1 - 4.8e-10 39.7 0.0 6.3e-07 29.6 0.0 3.5 3 0 0 3 3 3 2 C2 domain Pkinase PF00069.25 ORY48838.1 - 2.8e-09 36.7 0.0 7.8e-08 32.0 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY48838.1 - 2.4e-05 23.7 0.0 0.0034 16.7 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase malic PF00390.19 ORY48840.1 - 3e-60 203.1 0.0 4.4e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 ORY48840.1 - 4.7e-38 130.9 0.1 3.5e-37 128.1 0.1 2.0 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 ORY48841.1 - 5.3e-60 202.3 0.0 8.5e-60 201.7 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 ORY48841.1 - 9.3e-39 133.2 0.1 1.5e-38 132.6 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain HMG_box PF00505.19 ORY48842.1 - 3.6e-14 52.9 3.7 4.5e-14 52.6 3.7 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY48842.1 - 0.0064 17.1 2.1 0.0076 16.8 2.1 1.1 1 0 0 1 1 1 1 HMG-box domain Q_salvage PF10343.9 ORY48842.1 - 0.057 13.0 0.2 0.059 12.9 0.2 1.0 1 0 0 1 1 1 0 Potential Queuosine, Q, salvage protein family 4HBT PF03061.22 ORY48843.1 - 5.2e-09 36.3 0.0 8.6e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Chitin_synth_1 PF01644.17 ORY48844.1 - 1e-37 129.6 0.2 1.8e-35 122.3 0.2 2.4 1 1 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ORY48844.1 - 3.7e-18 65.3 0.2 9e-18 64.0 0.2 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ORY48844.1 - 3.8e-18 65.4 11.4 2.1e-06 26.7 0.0 3.5 3 1 1 4 4 4 3 Chitin synthase Glyco_trans_2_3 PF13632.6 ORY48844.1 - 1.9e-06 27.9 0.2 1.9e-06 27.9 0.2 2.3 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY48844.1 - 0.082 12.8 0.0 0.17 11.7 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase like family 2 Ac81 PF05820.11 ORY48844.1 - 0.15 11.6 4.3 0.5 9.9 4.3 1.8 1 0 0 1 1 1 0 Baculoviridae AC81 Chitin_synth_1 PF01644.17 ORY48846.1 - 3.3e-100 332.8 0.0 9.5e-62 207.8 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 ORY48846.1 - 1.8e-36 123.9 2.9 6.4e-18 64.5 0.0 2.9 3 0 0 3 3 3 2 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ORY48846.1 - 7.9e-33 113.9 11.6 2.8e-17 62.6 0.1 3.6 3 1 0 3 3 3 3 Chitin synthase Glyco_trans_2_3 PF13632.6 ORY48846.1 - 6.6e-12 45.7 0.1 1.2e-08 35.2 0.1 3.4 4 0 0 4 4 4 2 Glycosyl transferase family group 2 Med23 PF11573.8 ORY48846.1 - 0.0019 16.0 0.0 0.87 7.2 0.0 2.1 2 0 0 2 2 2 2 Mediator complex subunit 23 Glyco_tranf_2_3 PF13641.6 ORY48846.1 - 0.0031 17.4 0.0 1.2 8.9 0.0 2.9 3 0 0 3 3 3 2 Glycosyltransferase like family 2 Atg14 PF10186.9 ORY48846.1 - 0.1 11.7 0.0 6 5.9 0.0 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Chitin_synth_1 PF01644.17 ORY48847.1 - 4.5e-68 228.3 0.0 6.8e-68 227.8 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 ORY48847.1 - 4.8e-26 91.5 9.5 8.8e-22 77.4 0.0 2.5 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 ORY48847.1 - 5.4e-16 58.3 0.2 1.5e-15 56.9 0.2 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 ORY48847.1 - 7.9e-07 29.2 8.6 7.9e-07 29.2 8.6 2.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY48847.1 - 0.021 14.7 0.0 0.048 13.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Chitin_synth_1 PF01644.17 ORY48848.1 - 3.8e-65 218.8 0.1 5.7e-65 218.2 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 ORY48848.1 - 1.4e-23 83.4 7.6 6.9e-20 71.2 0.1 2.5 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 ORY48848.1 - 9.8e-18 63.9 0.2 3.4e-17 62.2 0.2 2.0 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 ORY48848.1 - 1.4e-11 44.7 0.4 1.4e-11 44.7 0.4 2.7 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY48848.1 - 0.00014 21.8 0.1 0.00051 20.0 0.0 2.0 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Ank_4 PF13637.6 ORY48849.1 - 5.1e-15 55.6 1.1 9.5e-05 22.9 0.0 4.7 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY48849.1 - 3.6e-12 46.7 2.4 0.0046 17.5 0.3 4.4 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.30 ORY48849.1 - 2.2e-08 34.2 1.1 1.5 9.4 0.0 6.9 7 0 0 7 7 7 2 Ankyrin repeat Ank_5 PF13857.6 ORY48849.1 - 7.5e-08 32.5 0.1 0.028 14.7 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY48849.1 - 7e-07 29.1 6.5 1.2 9.9 0.0 7.4 8 0 0 8 8 8 1 Ankyrin repeat Chitin_synth_1 PF01644.17 ORY48850.1 - 2.2e-68 229.4 0.0 3.2e-68 228.8 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 ORY48850.1 - 2.1e-25 89.4 3.7 3.1e-21 75.6 0.1 2.4 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 ORY48850.1 - 5.4e-17 61.5 0.2 1.2e-16 60.4 0.2 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 ORY48850.1 - 1.1e-08 35.3 5.9 1.1e-08 35.3 5.9 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY48850.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Hum_adeno_E3A PF05393.11 ORY48850.1 - 0.66 10.0 3.8 0.34 10.9 0.4 2.3 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein WSC PF01822.19 ORY48851.1 - 2.9e-06 27.4 1.2 2.9e-06 27.4 1.2 1.9 2 0 0 2 2 2 1 WSC domain Aspzincin_M35 PF14521.6 ORY48851.1 - 0.00052 20.6 0.1 0.0018 18.9 0.1 1.9 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Phosphodiest PF01663.22 ORY48852.1 - 4.1e-68 230.6 3.1 4.8e-68 230.4 3.1 1.0 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.12 ORY48852.1 - 0.097 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 PglZ domain Chitin_synth_1 PF01644.17 ORY48853.1 - 7.4e-62 208.1 0.0 1.3e-61 207.4 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 ORY48853.1 - 2.9e-24 85.6 3.6 2.6e-19 69.2 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.11 ORY48853.1 - 2.4e-19 69.1 0.2 5.1e-19 68.0 0.2 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 ORY48853.1 - 1e-08 35.4 0.0 1e-08 35.4 0.0 2.7 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY48853.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 TFIIA PF03153.13 ORY48853.1 - 3.1 7.7 23.5 6.2 6.7 23.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4064 PF13273.6 ORY48854.1 - 0.0038 17.5 0.5 0.0038 17.5 0.5 3.4 1 1 3 4 4 4 1 Protein of unknown function (DUF4064) CcmH PF03918.14 ORY48854.1 - 0.052 12.8 2.0 0.61 9.4 0.0 2.6 2 0 0 2 2 2 0 Cytochrome C biogenesis protein 2TM PF13239.6 ORY48854.1 - 0.36 11.2 0.1 0.36 11.2 0.1 3.3 2 1 1 3 3 3 0 2TM domain E1-E2_ATPase PF00122.20 ORY48854.1 - 2.2 7.7 16.5 0.58 9.7 0.3 2.9 2 1 1 3 3 3 0 E1-E2 ATPase DUF3187 PF11383.8 ORY48857.1 - 0.11 11.6 6.3 2.1 7.5 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3187) Opacity PF02462.15 ORY48857.1 - 1.8 8.7 10.5 70 3.5 2.1 4.9 1 1 1 2 2 2 0 Opacity family porin protein Transglycosylas PF06737.14 ORY48857.1 - 1.8 9.2 5.6 25 5.6 0.1 3.6 3 1 1 4 4 4 0 Transglycosylase-like domain MIF4G PF02854.19 ORY48861.1 - 3.3e-23 82.4 0.1 1.4e-22 80.4 0.0 2.0 2 1 0 2 2 2 1 MIF4G domain MA3 PF02847.17 ORY48861.1 - 1.4e-22 79.8 0.0 3.5e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 MA3 domain Nop14 PF04147.12 ORY48861.1 - 0.0032 15.8 17.0 0.0048 15.2 17.0 1.3 1 0 0 1 1 1 1 Nop14-like family YL1 PF05764.13 ORY48861.1 - 0.0056 16.8 17.2 0.0056 16.8 17.2 1.6 2 0 0 2 2 1 1 YL1 nuclear protein CDV3 PF15359.6 ORY48861.1 - 0.035 14.6 7.4 0.085 13.3 7.4 1.6 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 SDA1 PF05285.12 ORY48861.1 - 0.086 12.3 21.0 0.19 11.1 21.0 1.6 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.13 ORY48861.1 - 0.1 12.4 14.6 0.051 13.4 11.2 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region RRN3 PF05327.11 ORY48861.1 - 0.18 10.3 15.3 5.5 5.4 12.8 2.3 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 ORY48861.1 - 0.2 9.9 16.3 0.22 9.7 15.3 1.5 2 0 0 2 2 2 0 CDC45-like protein Lin-8 PF03353.15 ORY48861.1 - 0.74 9.3 4.5 1 8.9 4.5 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DNA_pol_phi PF04931.13 ORY48861.1 - 1.1 7.3 28.6 1.2 7.2 27.3 1.8 2 0 0 2 2 2 0 DNA polymerase phi Drc1-Sld2 PF11719.8 ORY48861.1 - 1.6 8.2 9.8 15 5.0 11.7 1.7 2 0 0 2 2 2 0 DNA replication and checkpoint protein Mpp10 PF04006.12 ORY48861.1 - 1.7 7.0 18.2 2.7 6.3 18.2 1.3 1 0 0 1 1 1 0 Mpp10 protein PDCD2_C PF04194.13 ORY48861.1 - 2.9 7.9 5.5 6.3 6.8 5.5 1.5 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain DUF2457 PF10446.9 ORY48861.1 - 5 6.1 30.1 8.8 5.3 30.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) adh_short PF00106.25 ORY48862.1 - 1.5e-29 102.9 1.0 5.2e-15 55.4 1.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY48862.1 - 2.2e-15 56.8 2.5 2e-08 34.1 1.6 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY48862.1 - 3.1e-07 30.5 0.8 9.9e-07 28.8 0.6 1.8 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.8 ORY48862.1 - 0.018 14.8 0.4 0.12 12.2 0.2 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pyr_redox_2 PF07992.14 ORY48862.1 - 0.044 13.0 0.4 0.098 11.9 0.2 1.6 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY48862.1 - 0.052 14.1 0.0 0.22 12.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 ORY48862.1 - 0.13 12.7 0.2 0.23 11.9 0.2 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Alginate_lyase2 PF08787.11 ORY48863.1 - 1.5e-29 103.5 0.0 3.1e-29 102.5 0.0 1.5 2 0 0 2 2 2 1 Alginate lyase Protocadherin PF08374.11 ORY48863.1 - 0.014 15.4 0.3 0.024 14.6 0.3 1.3 1 0 0 1 1 1 0 Protocadherin Polysacc_lyase PF14099.6 ORY48863.1 - 0.018 14.9 0.2 0.044 13.6 0.2 1.6 1 1 0 1 1 1 0 Polysaccharide lyase GAF_2 PF13185.6 ORY48863.1 - 0.06 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 GAF domain TRAM_LAG1_CLN8 PF03798.16 ORY48866.1 - 1.2e-36 126.3 17.3 2.2e-36 125.5 17.3 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 ORY48866.1 - 0.0013 18.3 2.2 0.0014 18.2 0.1 2.2 2 0 0 2 2 2 1 TRAM1-like protein DctQ PF04290.12 ORY48866.1 - 3.8 7.4 11.4 0.3 11.0 0.6 3.3 3 1 1 4 4 4 0 Tripartite ATP-independent periplasmic transporters, DctQ component Kinesin PF00225.23 ORY48867.1 - 1.1e-89 300.7 0.0 1.4e-89 300.4 0.0 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY48867.1 - 1.1e-24 87.1 0.0 1.8e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding adh_short PF00106.25 ORY48868.1 - 3.2e-35 121.4 0.8 1.3e-23 83.4 1.7 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY48868.1 - 1.2e-17 64.2 0.2 5e-14 52.4 0.8 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY48868.1 - 9.8e-15 54.9 3.0 4.3e-14 52.8 1.0 2.2 1 1 0 2 2 2 1 KR domain THF_DHG_CYH_C PF02882.19 ORY48868.1 - 1.8e-05 24.1 0.8 3.2e-05 23.3 0.8 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 ORY48868.1 - 0.00086 19.2 0.4 0.0019 18.1 0.4 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 ORY48868.1 - 0.014 15.8 0.3 0.024 15.1 0.3 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Epimerase PF01370.21 ORY48868.1 - 0.015 14.8 0.3 0.026 14.0 0.3 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family SMP_2 PF10144.9 ORY48868.1 - 0.09 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin WD40 PF00400.32 ORY48870.1 - 3e-11 43.7 0.0 0.00077 20.2 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY48870.1 - 2.7e-05 24.4 0.0 0.5 10.7 0.0 4.2 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 ORY48870.1 - 0.022 13.5 0.0 0.7 8.6 0.0 2.3 1 1 1 2 2 2 0 Nup133 N terminal like WD40_like PF17005.5 ORY48870.1 - 0.072 12.4 0.0 7.6 5.8 0.0 2.5 2 1 0 2 2 2 0 WD40-like domain bVLRF1 PF18826.1 ORY48872.1 - 1.1e-57 194.2 0.1 1.9e-57 193.3 0.1 1.4 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor VATC PF18716.1 ORY48872.1 - 1e-07 31.7 1.1 2.1e-07 30.7 1.1 1.5 1 0 0 1 1 1 1 Vms1-associating treble clef domain Ank PF00023.30 ORY48872.1 - 0.00029 21.2 0.1 0.00071 19.9 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 ORY48872.1 - 0.00046 20.7 0.0 0.00088 19.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY48872.1 - 0.0049 17.1 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY48872.1 - 0.058 14.0 0.0 0.14 12.8 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat zf-Sec23_Sec24 PF04810.15 ORY48872.1 - 0.29 11.2 1.6 0.75 9.9 1.6 1.6 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger zf-MYND PF01753.18 ORY48872.1 - 1.3 9.1 3.0 2.9 8.1 0.6 2.2 2 0 0 2 2 2 0 MYND finger YfhD PF14151.6 ORY48872.1 - 3 8.1 13.3 13 6.1 13.3 2.1 1 0 0 1 1 1 0 YfhD-like protein Snf7 PF03357.21 ORY48873.1 - 7.5e-07 28.9 15.0 1.7e-06 27.7 15.0 1.6 1 1 0 1 1 1 1 Snf7 TPR_MalT PF17874.1 ORY48873.1 - 0.0084 15.5 2.5 0.012 15.0 2.5 1.2 1 0 0 1 1 1 1 MalT-like TPR region Voltage_CLC PF00654.20 ORY48874.1 - 2.1e-97 326.5 28.1 4.2e-97 325.6 25.4 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 ORY48874.1 - 3.6e-05 24.1 0.0 0.0016 18.9 0.0 2.8 2 0 0 2 2 2 1 CBS domain Pex14_N PF04695.13 ORY48874.1 - 0.1 13.2 0.2 0.29 11.8 0.2 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Transgly_assoc PF04226.13 ORY48874.1 - 0.31 11.3 0.0 0.31 11.3 0.0 4.8 5 0 0 5 5 5 0 Transglycosylase associated protein Ferric_reduct PF01794.19 ORY48875.1 - 3.4e-18 66.0 8.0 3.4e-18 66.0 8.0 3.0 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ORY48875.1 - 6.7e-11 42.2 0.0 1.4e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 ORY48875.1 - 0.00045 20.4 0.0 0.00089 19.4 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain HEAT_EZ PF13513.6 ORY48876.1 - 1.1e-19 70.6 25.5 7.3e-10 39.1 0.1 9.8 10 1 1 11 11 10 3 HEAT-like repeat HEAT PF02985.22 ORY48876.1 - 2.5e-14 52.1 13.8 5.4e-05 23.1 0.0 9.1 10 0 0 10 10 9 4 HEAT repeat Vac14_Fab1_bd PF12755.7 ORY48876.1 - 3.7e-09 37.0 0.0 0.23 12.1 0.0 6.3 6 1 1 7 7 6 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 ORY48876.1 - 6.3e-09 36.1 4.9 0.017 15.5 0.1 7.4 4 3 7 11 11 11 2 HEAT repeats Adaptin_N PF01602.20 ORY48876.1 - 1.9e-06 26.7 1.5 0.012 14.2 0.4 3.1 3 1 0 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.7 ORY48876.1 - 2.7e-06 27.5 6.7 1 9.4 0.1 5.4 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 ORY48876.1 - 2.3e-05 24.2 0.1 0.00043 20.1 0.1 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF3437 PF11919.8 ORY48876.1 - 0.00018 21.3 0.1 9.6 6.2 0.0 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3437) MMS19_N PF14500.6 ORY48876.1 - 0.0017 18.0 1.2 1.9 8.0 0.4 4.1 3 1 1 5 5 5 1 Dos2-interacting transcription regulator of RNA-Pol-II RRN3 PF05327.11 ORY48876.1 - 0.0028 16.3 2.0 0.013 14.0 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 CLASP_N PF12348.8 ORY48876.1 - 0.0046 16.6 0.1 2 7.9 0.0 4.6 4 3 1 6 6 6 1 CLASP N terminal RXT2_N PF08595.11 ORY48876.1 - 0.0048 16.9 3.3 0.0096 16.0 3.3 1.4 1 0 0 1 1 1 1 RXT2-like, N-terminal Arm PF00514.23 ORY48876.1 - 0.0053 16.8 9.1 13 6.0 0.2 6.9 7 0 0 7 7 5 0 Armadillo/beta-catenin-like repeat Fanconi_A_N PF15865.5 ORY48876.1 - 0.0058 16.1 2.2 0.0061 16.0 0.5 1.8 2 0 0 2 2 2 1 Fanconi anaemia group A protein N terminus VHS PF00790.19 ORY48876.1 - 0.012 15.4 0.0 0.039 13.8 0.0 1.8 1 0 0 1 1 1 0 VHS domain DUF383 PF04063.14 ORY48876.1 - 0.015 15.0 0.3 0.1 12.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF383) DUF4611 PF15387.6 ORY48876.1 - 0.083 13.1 8.1 0.19 11.9 4.4 2.9 3 0 0 3 3 2 0 Domain of unknown function (DUF4611) Pox_Ag35 PF03286.14 ORY48876.1 - 0.35 10.6 4.0 0.6 9.9 4.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Cwf_Cwc_15 PF04889.12 ORY48876.1 - 0.85 9.3 12.3 1.3 8.6 12.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIF_alpha PF05793.12 ORY48876.1 - 1 7.9 13.1 1.4 7.4 13.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MFAP1 PF06991.11 ORY48876.1 - 2.5 7.9 9.1 4.3 7.1 9.1 1.3 1 0 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing PBP1_TM PF14812.6 ORY48876.1 - 2.7 8.4 10.6 5.5 7.4 10.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RNA_pol_3_Rpc31 PF11705.8 ORY48876.1 - 4.2 7.6 12.5 7.3 6.8 12.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2457 PF10446.9 ORY48876.1 - 6.7 5.7 11.8 11 5.0 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) OGG_N PF07934.12 ORY48878.1 - 6.3e-22 77.9 0.0 1e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 ORY48878.1 - 7.2e-15 55.4 0.0 1e-14 54.9 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 ORY48878.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif PQ-loop PF04193.14 ORY48879.1 - 1.7e-23 82.2 2.3 1.1e-12 47.5 0.3 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF4579 PF15158.6 ORY48879.1 - 1.1 9.0 3.5 1.1 8.9 2.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4579) LRR_4 PF12799.7 ORY48883.1 - 0.17 12.4 2.4 0.51 10.9 0.2 2.8 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.7 ORY48884.1 - 1.3e-21 76.3 30.5 3.2e-06 27.4 2.1 6.2 6 1 0 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY48884.1 - 1.3e-16 60.0 23.5 4.4e-05 23.2 6.3 5.9 2 2 4 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 ORY48884.1 - 7.3e-07 28.9 1.9 0.0008 19.0 0.0 3.1 2 1 1 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.33 ORY48884.1 - 0.002 18.4 17.9 26 5.9 0.5 8.8 7 2 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 ORY48884.1 - 0.017 15.2 22.3 1 9.6 0.5 6.4 6 0 0 6 6 6 0 Leucine Rich repeat Transglut_core PF01841.19 ORY48885.1 - 6.2e-08 33.1 0.0 3.1e-07 30.8 0.0 2.1 1 1 0 1 1 1 1 Transglutaminase-like superfamily LRR_8 PF13855.6 ORY48885.1 - 1.5e-06 27.8 1.4 3.1e-06 26.8 1.4 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 ORY48885.1 - 0.00077 19.8 1.3 0.0019 18.5 1.3 1.7 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY48885.1 - 0.0038 17.6 0.2 0.39 11.4 0.2 3.0 2 0 0 2 2 2 1 Leucine Rich Repeat Abp2 PF09441.10 ORY48886.1 - 6.1e-10 39.4 0.0 1.4e-09 38.3 0.0 1.5 1 1 0 1 1 1 1 ARS binding protein 2 ARID PF01388.21 ORY48886.1 - 1.8e-05 25.3 0.0 4.7e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF5399 PF17377.2 ORY48886.1 - 0.014 15.2 0.0 0.49 10.2 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5399) Phytochelatin PF05023.14 ORY48887.1 - 8.3e-76 253.9 0.0 1e-75 253.7 0.0 1.1 1 0 0 1 1 1 1 Phytochelatin synthase Chitin_synth_1 PF01644.17 ORY48890.1 - 1.3e-60 204.0 0.2 2.3e-60 203.3 0.2 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 ORY48890.1 - 1.6e-23 83.1 2.0 5.6e-19 68.1 0.0 3.0 3 0 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.11 ORY48890.1 - 1.5e-18 66.5 0.0 4.3e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 ORY48890.1 - 4.4e-06 26.7 6.0 4.4e-06 26.7 6.0 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY48890.1 - 0.001 19.0 0.0 0.0031 17.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Asp-B-Hydro_N PF05279.11 ORY48890.1 - 3.4 7.7 10.5 6.3 6.8 10.5 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region 3-PAP PF12578.8 ORY48891.1 - 0.66 9.7 2.2 2.1 8.1 0.2 2.3 1 1 1 2 2 2 0 Myotubularin-associated protein NAD_binding_10 PF13460.6 ORY48892.1 - 3.8e-10 40.0 2.1 7.4e-10 39.0 2.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding PgaPase_1 PF06162.12 ORY48892.1 - 0.58 9.9 2.5 0.44 10.3 0.2 1.9 2 1 0 2 2 2 0 Putative pyroglutamyl peptidase PgaPase_1 Abhydrolase_1 PF00561.20 ORY48893.1 - 7.4e-52 176.5 0.1 8.9e-52 176.3 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY48893.1 - 0.00021 22.0 0.0 0.00026 21.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Histidinol_dh PF00815.20 ORY48894.1 - 4.9e-159 529.7 0.1 7.5e-159 529.1 0.1 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 ORY48894.1 - 6e-24 83.7 0.1 2.2e-23 81.9 0.2 2.0 2 0 0 2 2 2 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 ORY48894.1 - 2.5e-15 56.7 0.5 2.1e-14 53.7 0.5 2.3 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 ORY48894.1 - 0.012 15.8 0.2 0.021 15.0 0.2 1.4 1 0 0 1 1 1 0 MazG nucleotide pyrophosphohydrolase domain Cnd2 PF05786.14 ORY48895.1 - 7.8e-140 468.0 7.9 6.5e-113 378.9 4.2 2.1 1 1 1 2 2 2 2 Condensin complex subunit 2 Ribosomal_S6e PF01092.19 ORY48895.1 - 0.049 13.6 1.4 0.2 11.6 0.0 2.5 3 0 0 3 3 3 0 Ribosomal protein S6e DUF4201 PF13870.6 ORY48897.1 - 0.0095 15.7 1.5 0.0095 15.7 1.5 5.5 3 2 2 5 5 5 1 Domain of unknown function (DUF4201) DUF16 PF01519.16 ORY48897.1 - 0.012 16.0 4.1 0.012 16.0 4.1 6.6 1 1 4 6 6 6 0 Protein of unknown function DUF16 Roc PF08477.13 ORY48899.1 - 1.3e-08 35.1 0.0 1.4e-08 34.9 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 ORY48899.1 - 0.00035 21.1 0.0 0.00043 20.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Arf PF00025.21 ORY48899.1 - 0.00049 19.6 0.0 0.00059 19.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 ORY48899.1 - 0.0021 17.7 0.0 0.0027 17.3 0.0 1.1 1 0 0 1 1 1 1 Ras family RNA_helicase PF00910.22 ORY48899.1 - 0.0081 16.5 0.0 0.0095 16.3 0.0 1.2 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 ORY48899.1 - 0.0094 16.2 0.0 0.011 16.0 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 ORY48899.1 - 0.016 15.7 0.0 0.02 15.3 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 ORY48899.1 - 0.034 14.4 0.0 0.06 13.6 0.0 1.5 1 1 1 2 2 2 0 AAA domain Mg_chelatase PF01078.21 ORY48899.1 - 0.043 13.2 0.0 0.055 12.8 0.0 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 ORY48899.1 - 0.05 13.3 0.0 0.07 12.8 0.0 1.2 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 ORY48899.1 - 0.052 12.6 0.0 0.087 11.9 0.0 1.4 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_16 PF13191.6 ORY48899.1 - 0.058 13.8 0.0 0.058 13.8 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 ORY48899.1 - 0.058 13.5 0.0 0.061 13.4 0.0 1.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 ORY48899.1 - 0.16 11.4 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Snf7 PF03357.21 ORY48900.1 - 7.4e-50 168.9 15.2 8.4e-50 168.7 15.2 1.0 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.12 ORY48900.1 - 0.00092 19.6 5.6 0.057 13.9 1.2 3.1 2 1 0 2 2 2 2 Nucleopolyhedrovirus P10 protein DUF1319 PF07028.11 ORY48900.1 - 0.0024 18.1 1.0 0.0024 18.1 1.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1319) Prominin PF05478.11 ORY48900.1 - 0.0094 14.0 3.5 0.011 13.7 3.5 1.2 1 1 0 1 1 1 1 Prominin Actin PF00022.19 ORY48900.1 - 0.013 14.1 0.3 0.015 13.9 0.3 1.1 1 0 0 1 1 1 0 Actin PRTP PF01366.18 ORY48900.1 - 0.13 10.3 2.2 0.17 9.9 2.2 1.0 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Glutaredoxin PF00462.24 ORY48900.1 - 0.38 11.0 0.2 0.38 11.0 0.2 2.4 3 0 0 3 3 3 0 Glutaredoxin PEP-utilisers_N PF05524.13 ORY48900.1 - 2.6 8.3 6.9 1.5 9.0 3.1 2.3 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DUF948 PF06103.11 ORY48900.1 - 2.6 8.4 6.0 17 5.8 3.6 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.11 ORY48900.1 - 3 8.3 14.2 2.4 8.6 3.3 3.7 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) XhlA PF10779.9 ORY48900.1 - 5.6 7.3 11.9 0.58 10.4 0.4 3.0 2 1 1 3 3 3 0 Haemolysin XhlA FapA PF03961.13 ORY48900.1 - 8.1 4.9 14.3 8.8 4.8 4.4 2.2 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF848 PF05852.11 ORY48900.1 - 8.2 6.5 10.3 0.66 10.1 4.1 2.2 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) DLH PF01738.18 ORY48901.1 - 3.8e-17 62.6 0.1 1.7e-16 60.5 0.1 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 ORY48901.1 - 0.0057 16.3 0.0 0.0074 15.9 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 ORY48902.1 - 8.7e-30 103.9 0.2 5.8e-29 101.2 0.2 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 ORY48902.1 - 0.00014 21.6 0.0 0.0023 17.7 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 ORY48902.1 - 0.0063 16.5 0.1 3 7.7 0.1 2.2 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 ORY48902.1 - 0.0065 16.0 0.0 0.055 12.9 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family KDZ PF18758.1 ORY48904.1 - 2.3e-26 92.8 0.0 4.1e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC1 PF18802.1 ORY48904.1 - 6.7e-06 26.2 0.4 1.8e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 CxC1 like cysteine cluster associated with KDZ transposases CxC2 PF18803.1 ORY48904.1 - 0.067 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 CxC2 like cysteine cluster associated with KDZ transposases DUF3523 PF12037.8 ORY48908.1 - 0.021 14.2 5.3 0.24 10.8 3.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3523) baeRF_family12 PF18856.1 ORY48908.1 - 0.3 11.6 2.7 1.8 9.1 0.2 2.4 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 Rsc14 PF08586.10 ORY48908.1 - 0.42 11.5 1.8 1.6 9.6 0.7 2.3 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit DLH PF01738.18 ORY48909.1 - 1.1e-27 97.0 0.0 2.5e-27 95.9 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 ORY48909.1 - 0.00014 21.6 0.0 0.00028 20.6 0.0 1.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold VMA21 PF09446.10 ORY48909.1 - 0.33 11.1 1.9 2 8.6 1.9 2.1 1 1 0 1 1 1 0 VMA21-like domain Ric8 PF10165.9 ORY48910.1 - 4.8e-90 302.8 0.3 1e-89 301.7 0.0 1.6 2 0 0 2 2 2 1 Guanine nucleotide exchange factor synembryn TEX15 PF15326.6 ORY48910.1 - 0.014 15.1 1.6 0.021 14.6 0.1 1.9 2 0 0 2 2 2 0 Testis expressed sequence 15 bZIP_2 PF07716.15 ORY48911.1 - 1.7e-05 24.8 16.2 0.00068 19.7 9.3 2.7 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 ORY48911.1 - 7.5e-05 22.7 12.0 0.0011 19.0 6.8 2.6 2 0 0 2 2 2 2 bZIP transcription factor RasGAP_C PF03836.15 ORY48911.1 - 0.00062 19.9 0.7 0.011 15.9 0.1 2.2 2 0 0 2 2 2 1 RasGAP C-terminus HAP1_N PF04849.13 ORY48911.1 - 0.0038 16.5 8.8 0.14 11.4 0.6 2.2 2 0 0 2 2 2 2 HAP1 N-terminal conserved region TSC22 PF01166.18 ORY48911.1 - 0.023 15.0 5.6 1.7 9.0 0.1 2.7 3 0 0 3 3 3 0 TSC-22/dip/bun family ZapB PF06005.12 ORY48911.1 - 2.3 8.7 16.8 2.8 8.4 5.5 2.7 2 2 0 2 2 2 0 Cell division protein ZapB CENP-H PF05837.12 ORY48911.1 - 2.7 8.4 10.9 3.4 8.1 0.2 2.7 3 0 0 3 3 3 0 Centromere protein H (CENP-H) UPF0242 PF06785.11 ORY48911.1 - 4.6 7.3 9.1 0.25 11.4 2.3 2.0 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus BRO1 PF03097.18 ORY48912.1 - 3.1e-116 388.4 0.6 6.8e-116 387.3 0.1 1.8 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 ORY48912.1 - 1.5e-53 182.0 3.1 3.1e-53 181.0 3.1 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV WXG100 PF06013.12 ORY48912.1 - 0.26 11.6 4.1 0.39 11.0 0.3 3.3 3 1 0 3 3 3 0 Proteins of 100 residues with WXG PAP_central PF04928.17 ORY48913.1 - 8.7e-107 355.7 0.0 1.1e-106 355.4 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 ORY48913.1 - 4.9e-48 163.0 0.0 8.1e-48 162.3 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 ORY48913.1 - 1.9e-10 40.9 0.0 4.4e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 ORY48913.1 - 0.066 13.0 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain GCD14 PF08704.10 ORY48914.1 - 2.8e-85 286.0 0.0 3.3e-85 285.7 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 ORY48914.1 - 0.00051 19.8 0.0 0.00092 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 ORY48914.1 - 0.0016 18.2 0.0 0.0041 16.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Gcd10p PF04189.13 ORY48914.1 - 0.015 14.4 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Gcd10p family DUF4746 PF15928.5 ORY48914.1 - 0.17 11.3 1.8 0.23 10.8 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TPP_enzyme_N PF02776.18 ORY48915.1 - 4.7e-56 189.1 0.1 1e-55 188.0 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 ORY48915.1 - 1.1e-46 158.4 0.1 4.1e-45 153.3 0.0 3.0 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 ORY48915.1 - 7.3e-40 135.9 0.1 1.9e-39 134.6 0.1 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 ORY48915.1 - 0.03 14.1 0.1 0.1 12.3 0.1 1.9 2 0 0 2 2 2 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg WD40 PF00400.32 ORY48916.1 - 8.1e-09 36.0 11.3 0.29 12.1 0.0 7.7 8 0 0 8 8 8 4 WD domain, G-beta repeat HEAT_2 PF13646.6 ORY48916.1 - 0.00015 22.0 0.0 0.00055 20.3 0.0 2.0 1 0 0 1 1 1 1 HEAT repeats ANAPC4_WD40 PF12894.7 ORY48916.1 - 0.0014 18.9 0.1 7.9 6.9 0.0 3.9 3 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain HEAT PF02985.22 ORY48916.1 - 0.067 13.5 0.0 3.4 8.2 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat Methyltransf_16 PF10294.9 ORY48918.1 - 8.8e-09 35.3 0.0 1.3e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 ORY48918.1 - 0.053 14.3 0.0 0.091 13.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 ORY48918.1 - 0.12 11.7 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ORY48918.1 - 0.13 11.9 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 ORY48918.1 - 0.15 12.8 0.0 0.29 11.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 ORY48918.1 - 0.2 11.5 0.0 0.26 11.1 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain Ribophorin_I PF04597.14 ORY48919.1 - 2.2e-72 244.7 1.4 8.8e-70 236.1 1.4 3.4 1 1 0 1 1 1 1 Ribophorin I GARP PF16731.5 ORY48919.1 - 4.9 6.8 12.1 0.11 12.2 3.2 2.1 2 0 0 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma PolyA_pol_RNAbd PF12627.7 ORY48920.1 - 0.033 14.0 0.4 0.34 10.7 0.0 2.6 3 0 0 3 3 3 0 Probable RNA and SrmB- binding site of polymerase A DUF4106 PF13388.6 ORY48921.1 - 9.7 5.3 6.6 11 5.1 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) FKBP_C PF00254.28 ORY48922.1 - 3e-19 69.1 0.2 1.2e-18 67.2 0.1 1.9 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4400 PF14348.6 ORY48923.1 - 0.063 12.8 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) Galactosyl_T PF01762.21 ORY48924.1 - 9.3e-05 22.3 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase AAA PF00004.29 ORY48925.1 - 5.6e-07 30.0 0.4 4.6e-06 27.1 0.4 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 ORY48925.1 - 0.00011 22.8 0.6 0.013 16.1 0.6 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY48925.1 - 0.0045 17.4 0.4 0.013 15.9 0.1 1.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 ORY48925.1 - 0.0047 16.9 0.0 0.026 14.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 ORY48925.1 - 0.0082 16.7 0.1 0.015 15.8 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_15 PF13175.6 ORY48925.1 - 0.013 15.3 1.1 0.02 14.6 1.1 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 ORY48925.1 - 0.023 14.5 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.6 ORY48925.1 - 0.026 14.9 6.8 1.2 9.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain ATPase PF06745.13 ORY48925.1 - 0.07 12.5 2.9 0.18 11.1 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_7 PF12775.7 ORY48925.1 - 0.079 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_28 PF13521.6 ORY48925.1 - 0.14 12.4 0.9 0.43 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 ORY48925.1 - 0.33 10.7 2.3 15 5.3 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_11 PF13086.6 ORY48925.1 - 0.98 9.1 0.0 0.98 9.1 0.0 2.2 1 1 1 2 2 2 0 AAA domain ParB PF08775.10 ORY48925.1 - 8.7 6.8 10.1 10 6.6 1.3 2.3 1 1 1 2 2 2 0 ParB family TOM13 PF08219.11 ORY48926.1 - 0.0028 17.6 0.0 0.0037 17.2 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein TOM13 Iso_dh PF00180.20 ORY48927.1 - 7.2e-70 235.8 0.0 1.9e-66 224.6 0.0 3.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Arrestin_N PF00339.29 ORY48928.1 - 1e-05 25.6 0.0 5.4e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 ORY48928.1 - 0.081 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Arrestin_N terminal like Extensin_2 PF04554.13 ORY48928.1 - 0.17 11.9 14.1 0.32 11.1 14.1 1.4 1 0 0 1 1 1 0 Extensin-like region CYYR1 PF10873.8 ORY48928.1 - 0.26 11.7 1.2 0.44 11.0 1.2 1.3 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 VPS9 PF02204.18 ORY48929.1 - 2.4e-24 85.5 0.4 4.2e-24 84.8 0.4 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 ORY48929.1 - 0.023 15.0 0.0 0.075 13.3 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) DUF1292 PF06949.11 ORY48929.1 - 0.084 13.8 0.4 1 10.3 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1292) SKG6 PF08693.10 ORY48930.1 - 0.019 14.4 2.0 0.049 13.0 2.0 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pkinase PF00069.25 ORY48931.1 - 1.5e-50 172.1 0.0 3e-32 112.0 0.0 3.2 2 1 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 ORY48931.1 - 4.5e-26 91.7 0.0 5.6e-20 71.7 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY48931.1 - 0.00017 20.5 1.3 0.0003 19.7 0.1 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 ORY48931.1 - 0.0075 15.6 0.0 1.7 7.9 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 ORY48931.1 - 0.045 13.7 0.1 0.094 12.6 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF1679 PF07914.11 ORY48931.1 - 0.058 12.3 0.3 5.1 5.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) DUF5383 PF17355.2 ORY48932.1 - 0.18 12.2 0.1 0.37 11.2 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5383) OCRE PF17780.1 ORY48932.1 - 0.45 10.6 14.2 0.54 10.3 10.0 2.3 2 0 0 2 2 2 0 OCRE domain NTP_transf_9 PF04248.12 ORY48933.1 - 6.2e-31 106.1 1.9 6.9e-31 106.0 1.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Pilin_GH PF16734.5 ORY48933.1 - 0.048 14.0 0.5 0.061 13.6 0.5 1.1 1 0 0 1 1 1 0 Type IV pilin-like G and H, putative MAGE_N PF12440.8 ORY48936.1 - 0.034 14.8 4.1 0.034 14.8 4.1 3.6 3 0 0 3 3 3 0 Melanoma associated antigen family N terminal SH3_2 PF07653.17 ORY48936.1 - 0.072 12.8 0.2 8.4 6.2 0.0 2.5 2 0 0 2 2 2 0 Variant SH3 domain XPA_C PF05181.12 ORY48937.1 - 7.9e-22 77.0 3.8 1.9e-21 75.8 3.8 1.7 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 ORY48937.1 - 0.026 14.6 5.6 0.026 14.6 5.6 2.5 3 0 0 3 3 3 0 XPA protein N-terminal Elf1 PF05129.13 ORY48937.1 - 0.44 10.6 7.9 0.25 11.4 0.5 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-AD PF07776.15 ORY48937.1 - 5.8 7.2 9.8 9.9 6.5 1.0 3.0 2 1 1 3 3 3 0 Zinc-finger associated domain (zf-AD) Apt1 PF10351.9 ORY48940.1 - 0.05 12.5 8.3 0.065 12.1 8.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Period_C PF12114.8 ORY48940.1 - 2.8 7.5 23.7 4.6 6.8 23.7 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region HlyIII PF03006.20 ORY48942.1 - 1.4e-40 139.4 24.7 1.7e-40 139.1 24.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related HlyIII PF03006.20 ORY48943.1 - 1.8e-43 148.9 26.2 2.3e-43 148.5 26.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related Lactate_perm PF02652.14 ORY48944.1 - 0.0057 15.4 0.2 0.0063 15.3 0.2 1.0 1 0 0 1 1 1 1 L-lactate permease COG5 PF10392.9 ORY48945.1 - 2.1e-27 95.9 0.8 2.1e-27 95.9 0.8 2.6 3 0 0 3 3 3 1 Golgi transport complex subunit 5 COG2 PF06148.11 ORY48945.1 - 1.3e-07 31.8 0.5 1.3e-07 31.8 0.5 2.2 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 ORY48945.1 - 0.00018 21.5 0.1 0.00082 19.4 0.1 2.3 1 1 0 1 1 1 1 Vps51/Vps67 Zw10 PF06248.13 ORY48945.1 - 0.00038 19.2 3.5 0.00079 18.1 3.5 1.5 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Vps54_N PF10475.9 ORY48945.1 - 0.015 14.6 0.4 0.04 13.2 0.4 1.7 1 0 0 1 1 1 0 Vacuolar-sorting protein 54, of GARP complex DASH_Duo1 PF08651.10 ORY48945.1 - 0.049 13.4 0.3 1 9.2 0.5 3.0 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF1351 PF07083.11 ORY48945.1 - 0.061 13.1 0.2 0.17 11.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) Baculo_PEP_C PF04513.12 ORY48945.1 - 1.3 9.1 9.1 0.13 12.3 1.1 3.2 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus YlqD PF11068.8 ORY48945.1 - 4 7.8 7.8 0.23 11.8 0.2 2.6 3 0 0 3 3 3 0 YlqD protein XPA_C PF05181.12 ORY48946.1 - 1.3e-20 73.0 4.4 2.5e-20 72.2 4.4 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 ORY48946.1 - 0.00035 20.6 2.6 0.00035 20.6 2.6 2.0 2 0 0 2 2 2 1 XPA protein N-terminal Zn_Tnp_IS1595 PF12760.7 ORY48946.1 - 0.031 14.3 0.9 0.12 12.4 0.2 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain ArfGap PF01412.18 ORY48946.1 - 0.05 13.7 0.1 0.05 13.7 0.1 2.1 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf SOSSC PF15925.5 ORY48946.1 - 0.093 14.0 0.2 0.2 13.0 0.2 1.6 1 0 0 1 1 1 0 SOSS complex subunit C RNA_POL_M_15KD PF02150.16 ORY48946.1 - 0.23 11.3 2.1 15 5.6 0.0 3.2 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit CPSase_L_D2 PF02786.17 ORY48947.1 - 1.8e-101 338.0 0.0 9.4e-84 280.1 0.0 2.6 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 ORY48947.1 - 1.8e-37 128.4 0.0 3.5e-37 127.5 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 ORY48947.1 - 7.9e-13 48.3 0.0 7.7e-07 28.8 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ORY48947.1 - 5.4e-11 42.4 0.2 0.00058 19.4 0.0 3.1 3 0 0 3 3 3 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 ORY48947.1 - 5.8e-08 32.5 0.1 0.034 13.9 0.0 3.5 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 ORY48947.1 - 2e-05 24.2 0.0 0.0045 16.5 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.11 ORY48947.1 - 0.00019 21.1 0.0 0.59 9.7 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 ORY48947.1 - 0.00067 19.7 0.0 0.68 10.0 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain YAF2_RYBP PF17219.3 ORY48948.1 - 0.13 11.9 0.8 0.67 9.6 0.0 2.1 2 0 0 2 2 2 0 Yaf2/RYBP C-terminal binding motif HMG_box PF00505.19 ORY48949.1 - 8.9e-10 38.8 3.6 7.7 7.0 0.0 7.1 7 0 0 7 7 7 7 HMG (high mobility group) box OGFr_N PF04664.13 ORY48949.1 - 0.008 15.7 1.6 1.3e+02 2.0 0.0 5.7 2 2 5 7 7 7 0 Opioid growth factor receptor (OGFr) conserved region Peptidase_M3 PF01432.20 ORY48950.1 - 6.9e-140 467.3 0.8 9.1e-140 466.9 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M3 Methyltransf_24 PF13578.6 ORY48950.1 - 0.2 12.7 0.6 0.87 10.6 0.3 2.3 2 0 0 2 2 2 0 Methyltransferase domain Med31 PF05669.12 ORY48951.1 - 6.5e-34 115.8 8.3 7e-34 115.7 8.3 1.0 1 0 0 1 1 1 1 SOH1 Thioredoxin PF00085.20 ORY48954.1 - 9.5e-27 93.0 0.1 1.4e-26 92.4 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 ORY48954.1 - 5.1e-05 23.2 0.0 6.6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 ORY48954.1 - 6.3e-05 22.5 0.0 7.8e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 ORY48954.1 - 6.4e-05 23.2 0.0 0.0001 22.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 ORY48954.1 - 0.00013 22.4 0.1 0.0019 18.6 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 ORY48954.1 - 0.0036 17.1 0.0 0.0044 16.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 ORY48954.1 - 0.0061 16.7 0.2 0.02 15.1 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like Glutaredoxin PF00462.24 ORY48954.1 - 0.2 11.9 0.1 0.2 11.9 0.1 1.9 2 0 0 2 2 2 0 Glutaredoxin HMG_box PF00505.19 ORY48955.1 - 8.1e-23 80.6 15.5 3.1e-12 46.7 0.9 3.4 3 2 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY48955.1 - 3.5e-14 53.2 4.6 6.5e-09 36.3 1.0 2.7 2 0 0 2 2 2 2 HMG-box domain baeRF_family3 PF18845.1 ORY48955.1 - 4.2 7.6 6.9 3.6 7.8 0.2 2.9 2 1 2 4 4 4 0 Bacterial archaeo-eukaryotic release factor family 3 zf-RING_2 PF13639.6 ORY48957.1 - 9e-14 51.5 6.0 1.3e-13 51.0 6.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORY48957.1 - 5.4e-11 42.0 3.6 5.4e-11 42.0 3.6 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 ORY48957.1 - 1.6e-10 40.7 4.8 2.4e-10 40.1 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY48957.1 - 5.8e-09 35.6 5.2 9.2e-09 35.0 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY48957.1 - 2.7e-07 30.5 5.3 3.9e-07 29.9 5.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 ORY48957.1 - 2.2e-06 27.9 8.1 1.6e-05 25.1 8.1 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ORY48957.1 - 4.3e-06 26.6 3.4 8.1e-06 25.8 3.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORY48957.1 - 1.9e-05 24.4 2.0 2.7e-05 23.9 2.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY48957.1 - 0.00037 20.3 5.3 0.0008 19.2 5.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 ORY48957.1 - 0.0013 18.3 5.4 0.0018 17.8 5.0 1.4 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 ORY48957.1 - 0.0019 18.2 6.2 0.021 14.8 6.2 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 ORY48957.1 - 0.0068 16.2 3.5 0.012 15.4 3.5 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RINGv PF12906.7 ORY48957.1 - 0.014 15.5 3.0 0.03 14.5 3.0 1.5 1 1 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 ORY48957.1 - 0.039 14.3 2.2 0.079 13.3 2.2 1.5 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 ORY48957.1 - 0.048 13.8 7.4 0.2 11.9 7.4 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_6 PF14835.6 ORY48957.1 - 0.054 13.4 1.8 0.11 12.4 1.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_9 PF13901.6 ORY48957.1 - 0.058 13.4 1.0 0.077 13.0 1.0 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-C3H2C3 PF17122.5 ORY48957.1 - 0.3 11.2 5.0 0.66 10.1 5.0 1.7 1 1 0 1 1 1 0 Zinc-finger PHD PF00628.29 ORY48957.1 - 0.48 10.4 5.5 0.87 9.5 5.5 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 ORY48957.1 - 1.8 8.8 6.1 8.7 6.6 6.2 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_1 PF14446.6 ORY48957.1 - 8.9 6.3 7.1 2.2 8.2 1.1 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 CWC25 PF12542.8 ORY48958.1 - 1e-25 90.6 0.6 1e-25 90.6 0.6 5.1 3 1 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 ORY48958.1 - 1.3e-12 47.7 8.3 1.3e-12 47.7 8.3 5.2 5 0 0 5 5 5 1 N-terminal domain of CBF1 interacting co-repressor CIR LptF_LptG PF03739.14 ORY48959.1 - 0.34 9.7 2.3 0.51 9.1 1.7 1.5 1 1 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG NPR1_interact PF15699.5 ORY48959.1 - 0.4 11.3 7.8 0.14 12.8 4.3 2.1 2 0 0 2 2 2 0 NPR1 interacting LSM PF01423.22 ORY48960.1 - 3.1e-08 33.2 0.0 5.6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 LSM domain DUF3147 PF11345.8 ORY48961.1 - 0.0031 17.8 4.3 0.0062 16.9 4.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3147) EMP70 PF02990.16 ORY48961.1 - 0.25 9.9 1.7 0.97 8.0 1.5 1.8 1 1 0 1 1 1 0 Endomembrane protein 70 EF-hand_1 PF00036.32 ORY48962.1 - 4.6e-18 63.3 6.2 0.00012 21.4 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 ORY48962.1 - 9.1e-18 62.6 2.1 3.2e-05 23.5 0.9 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 ORY48962.1 - 8.8e-16 58.1 5.9 1.7e-10 41.2 0.3 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 ORY48962.1 - 8.7e-10 37.7 6.1 0.0051 16.2 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 ORY48962.1 - 2.1e-08 33.9 1.5 0.005 16.7 0.2 3.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 ORY48962.1 - 0.0019 18.1 2.5 1.2 9.1 0.4 3.2 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORY48962.1 - 0.0025 18.1 4.2 0.071 13.4 0.1 3.2 2 2 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 ORY48962.1 - 0.15 12.4 0.3 8.1 6.8 0.0 2.8 2 1 1 3 3 3 0 EF-hand domain DUF2315 PF10231.9 ORY48962.1 - 1.4 9.1 4.8 0.72 10.0 1.6 1.9 1 1 1 2 2 2 0 Apoptogenic protein 1 zf-CCCH PF00642.24 ORY48963.1 - 0.1 12.6 4.2 0.18 11.8 4.2 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Bac_rhamnosid_C PF17390.2 ORY48964.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase C-terminal domain Tom7 PF08038.12 ORY48965.1 - 1.1e-13 50.5 0.1 1.4e-13 50.2 0.1 1.1 1 0 0 1 1 1 1 TOM7 family Fe_dep_repr_C PF02742.15 ORY48965.1 - 0.1 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain DNA_pol_A_exo1 PF01612.20 ORY48966.1 - 2.5e-06 27.3 0.0 4.7e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease PAM2 PF07145.15 ORY48966.1 - 0.077 12.7 0.1 0.35 10.7 0.1 2.1 1 0 0 1 1 1 0 Ataxin-2 C-terminal region MukB PF04310.12 ORY48966.1 - 0.077 12.8 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 MukB N-terminal Antimicrobial18 PF08130.11 ORY48966.1 - 0.16 12.1 0.1 0.36 11.0 0.1 1.5 1 0 0 1 1 1 0 Type A lantibiotic family MscS_porin PF12795.7 ORY48966.1 - 0.29 10.7 11.7 3.4 7.2 12.3 2.0 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain Laminin_II PF06009.12 ORY48966.1 - 1.1 9.3 5.6 3.7 7.6 0.1 2.5 2 0 0 2 2 2 0 Laminin Domain II Ank_2 PF12796.7 ORY48967.1 - 1.5e-15 57.5 0.0 1.9e-06 28.3 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY48967.1 - 2.6e-14 51.9 0.3 0.02 15.4 0.0 6.0 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 ORY48967.1 - 2.1e-12 47.0 0.6 0.015 15.6 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ion_trans PF00520.31 ORY48967.1 - 5.9e-12 45.3 20.9 9e-12 44.7 20.9 1.3 1 0 0 1 1 1 1 Ion transport protein Ank_4 PF13637.6 ORY48967.1 - 1.8e-11 44.3 1.2 0.0014 19.1 0.0 4.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY48967.1 - 1e-09 38.4 0.1 0.45 11.1 0.0 5.1 4 0 0 4 4 4 3 Ankyrin repeat PKD_channel PF08016.12 ORY48967.1 - 0.23 10.1 14.3 0.043 12.5 9.8 2.0 1 1 1 2 2 2 0 Polycystin cation channel 2-Hacid_dh_C PF02826.19 ORY48968.1 - 2.3e-55 186.7 0.0 4.3e-55 185.8 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY48968.1 - 3.9e-24 84.8 0.0 3e-23 82.0 0.0 1.9 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain cNMP_binding PF00027.29 ORY48968.1 - 2.4e-15 56.4 0.0 4.7e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain NAD_binding_2 PF03446.15 ORY48968.1 - 0.00062 20.0 0.8 0.0014 18.8 0.1 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 ORY48968.1 - 0.0074 16.3 0.1 0.31 11.1 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 ORY48968.1 - 0.0091 15.9 0.2 0.024 14.5 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Peptidase_M3 PF01432.20 ORY48968.1 - 0.01 15.1 0.6 0.016 14.5 0.6 1.2 1 0 0 1 1 1 0 Peptidase family M3 NAD_binding_7 PF13241.6 ORY48968.1 - 0.038 14.4 0.0 0.14 12.6 0.0 2.0 1 0 0 1 1 1 0 Putative NAD(P)-binding IlvN PF07991.12 ORY48968.1 - 0.088 12.4 0.0 0.22 11.1 0.0 1.7 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 ORY48968.1 - 0.089 12.9 0.2 0.23 11.5 0.2 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TLD PF07534.16 ORY48969.1 - 4e-15 56.3 0.0 8e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 TLD RabGAP-TBC PF00566.18 ORY48969.1 - 1.7e-12 47.5 1.0 3.3e-10 40.0 0.1 2.7 3 0 0 3 3 3 2 Rab-GTPase-TBC domain DUF647 PF04884.14 ORY48971.1 - 1.4e-69 234.4 0.6 2.2e-69 233.8 0.6 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Nucleoporin_FG2 PF15967.5 ORY48971.1 - 0.013 14.1 0.5 0.013 14.1 0.5 2.1 2 0 0 2 2 2 0 Nucleoporin FG repeated region DUF1538 PF07556.11 ORY48971.1 - 0.13 11.6 2.2 0.13 11.5 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1538) MPC PF03650.13 ORY48972.1 - 2.4e-35 121.0 0.1 3e-35 120.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Zn_clus PF00172.18 ORY48973.1 - 0.00012 22.1 9.7 0.00024 21.1 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 ORY48973.1 - 0.00025 21.0 0.0 0.00058 19.8 0.0 1.6 1 0 0 1 1 1 1 PAS fold zf-RING_2 PF13639.6 ORY48974.1 - 3.4e-10 40.1 9.3 6.3e-10 39.2 9.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 ORY48974.1 - 6.9e-08 32.7 6.6 1.7e-07 31.4 6.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ORY48974.1 - 6.1e-06 26.2 2.9 1.2e-05 25.2 2.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 ORY48974.1 - 1.2e-05 24.9 1.2 2.4e-05 24.0 1.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 ORY48974.1 - 1.3e-05 25.1 2.5 3e-05 24.0 2.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 ORY48974.1 - 2.3e-05 24.1 9.4 4.1e-05 23.3 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY48974.1 - 3.3e-05 23.7 4.6 6.2e-05 22.8 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 ORY48974.1 - 0.00011 22.0 0.3 0.19 11.6 0.0 3.6 3 0 0 3 3 3 1 Rad50 zinc hook motif FANCL_C PF11793.8 ORY48974.1 - 0.00013 22.1 3.4 0.00048 20.3 3.4 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain Prok-RING_1 PF14446.6 ORY48974.1 - 0.00098 19.0 5.0 0.0072 16.2 1.6 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.6 ORY48974.1 - 0.0016 18.2 6.1 0.0029 17.4 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 ORY48974.1 - 0.005 16.6 3.7 0.0088 15.8 3.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 ORY48974.1 - 0.045 13.7 6.7 0.13 12.2 6.9 1.7 1 1 0 1 1 1 0 zinc-RING finger domain Phi-29_GP16_7 PF06720.11 ORY48974.1 - 0.1 12.4 0.7 0.8 9.5 0.1 2.2 2 0 0 2 2 2 0 Bacteriophage phi-29 early protein GP16.7 YacG PF03884.14 ORY48974.1 - 0.46 10.3 4.1 2.9 7.7 0.5 2.7 1 1 1 2 2 2 0 DNA gyrase inhibitor YacG Zn_ribbon_17 PF17120.5 ORY48974.1 - 2.3 7.9 5.7 4.3 7.0 5.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 ORY48974.1 - 2.8 7.9 10.9 4.9 7.1 7.9 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 RINGv PF12906.7 ORY48974.1 - 7.6 6.8 8.0 3.3 7.9 5.1 2.0 2 1 0 2 2 2 0 RING-variant domain HMG_box PF00505.19 ORY48975.1 - 0.00028 21.2 0.3 7.8 7.0 0.0 3.2 3 0 0 3 3 3 3 HMG (high mobility group) box EBP PF05241.12 ORY48975.1 - 0.0019 17.7 0.2 3.7 7.0 0.0 3.1 3 0 0 3 3 3 3 Emopamil binding protein EI24 PF07264.11 ORY48977.1 - 9.5e-07 29.2 12.9 0.00072 19.8 11.7 3.2 1 1 1 2 2 2 2 Etoposide-induced protein 2.4 (EI24) DUF4663 PF15668.5 ORY48978.1 - 0.78 8.7 4.5 1.2 8.2 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) Amidohydro_1 PF01979.20 ORY48979.1 - 1.2e-61 208.9 0.0 1.1e-60 205.8 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY48979.1 - 2.3e-09 37.2 0.0 0.00063 19.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family DUF1697 PF08002.11 ORY48980.1 - 2.1e-30 106.0 0.0 3e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1697) Hydrolase_4 PF12146.8 ORY48981.1 - 3.5e-17 62.5 0.0 5.6e-10 38.9 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY48981.1 - 7.6e-11 42.1 0.0 7.7e-09 35.6 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 ORY48981.1 - 1e-08 35.3 0.0 9.4e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 ORY48981.1 - 6.5e-06 25.8 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 ORY48981.1 - 0.00011 22.9 0.0 0.00039 21.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 ORY48981.1 - 0.0021 18.0 0.0 0.0065 16.3 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase BAAT_C PF08840.11 ORY48981.1 - 0.018 14.9 0.0 0.11 12.4 0.0 2.1 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_4 PF08386.10 ORY48981.1 - 0.059 13.5 0.0 1.7 8.8 0.0 2.2 2 0 0 2 2 2 0 TAP-like protein DUF2920 PF11144.8 ORY48981.1 - 0.084 12.0 0.1 0.62 9.2 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2920) UPF0261 PF06792.11 ORY48981.1 - 0.2 10.6 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) Zw10 PF06248.13 ORY48982.1 - 2.1e-19 69.5 0.7 2.9e-19 69.1 0.7 1.0 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Imm7 PF15585.6 ORY48982.1 - 0.08 13.2 0.8 0.26 11.6 0.1 2.3 2 0 0 2 2 2 0 Immunity protein 7 Spc7 PF08317.11 ORY48982.1 - 0.75 8.6 5.7 1.2 7.9 5.7 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Zw10 PF06248.13 ORY48983.1 - 8.3e-19 67.6 0.0 1.2e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 ORY48983.1 - 0.0006 19.6 0.1 0.0058 16.4 0.1 2.3 1 1 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Branch_AA_trans PF05525.13 ORY48983.1 - 0.16 10.8 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Branched-chain amino acid transport protein Med13_C PF06333.12 ORY48986.1 - 5.6 6.1 11.5 0.29 10.4 3.4 2.0 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain LisH_2 PF16045.5 ORY48988.1 - 0.12 11.5 1.6 0.62 9.1 0.2 2.5 2 0 0 2 2 2 0 LisH MFS_1 PF07690.16 ORY48989.1 - 7.3e-37 127.1 29.5 8.5e-37 126.9 29.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3342 PF11822.8 ORY48990.1 - 1.1e-18 67.3 0.8 3e-18 65.8 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) BTB PF00651.31 ORY48990.1 - 0.028 14.6 0.1 0.051 13.8 0.1 1.4 1 0 0 1 1 1 0 BTB/POZ domain CHORD PF04968.12 ORY48990.1 - 0.033 14.9 1.6 0.083 13.6 1.6 1.7 1 1 0 1 1 1 0 CHORD cNMP_binding PF00027.29 ORY48991.1 - 7.6e-17 61.2 0.0 1.8e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF2441 PF10386.9 ORY48991.1 - 0.0081 16.2 0.3 0.015 15.3 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2441) cNMP_binding PF00027.29 ORY48993.1 - 1.5e-18 66.6 0.0 2.4e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Cupin_3 PF05899.12 ORY48993.1 - 0.043 13.5 0.3 0.66 9.7 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF861) Ion_trans PF00520.31 ORY48994.1 - 0.064 12.5 3.3 0.078 12.2 3.3 1.2 1 0 0 1 1 1 0 Ion transport protein GTP_EFTU PF00009.27 ORY48996.1 - 3.9e-50 170.1 0.0 7.2e-50 169.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 ORY48996.1 - 5.3e-19 68.0 0.0 1.1e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus FHA PF00498.26 ORY48996.1 - 2e-13 50.4 0.0 6.8e-13 48.8 0.0 1.9 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 ORY48996.1 - 3.2e-09 36.4 13.5 9.2e-09 34.9 13.5 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 ORY48996.1 - 4e-07 30.3 17.1 9.1e-07 29.1 17.1 1.7 1 0 0 1 1 1 1 Ring finger domain GTP_EFTU_D2 PF03144.25 ORY48996.1 - 4e-07 30.3 0.2 1.6e-06 28.4 0.2 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY48996.1 - 7.4e-05 22.8 0.0 0.00022 21.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Yop-YscD_cpl PF16697.5 ORY48996.1 - 0.00062 20.0 0.0 0.0021 18.4 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-ANAPC11 PF12861.7 ORY48996.1 - 0.00071 19.6 7.4 0.0015 18.5 7.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RsgA_GTPase PF03193.16 ORY48996.1 - 0.0041 17.0 0.0 0.049 13.5 0.0 2.2 1 1 0 2 2 2 1 RsgA GTPase zf-rbx1 PF12678.7 ORY48996.1 - 0.0094 16.2 11.7 0.024 14.9 11.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain FeoB_N PF02421.18 ORY48996.1 - 0.028 13.9 0.0 0.091 12.3 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B NPCBM_assoc PF10633.9 ORY48996.1 - 0.077 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Septin PF00735.18 ORY48996.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Septin zf-C3HC4_2 PF13923.6 ORY48996.1 - 0.67 9.8 18.4 1.9 8.4 18.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY48996.1 - 1.1 9.3 20.6 0.31 11.0 16.8 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 ORY48996.1 - 1.3 9.0 23.9 0.094 12.6 18.4 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ABC_tran PF00005.27 ORY48998.1 - 2.9e-29 102.3 0.0 4.6e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 ORY48998.1 - 1.9e-15 56.9 16.2 1.8e-13 50.4 3.9 3.0 2 1 1 3 3 3 2 ABC-2 type transporter AAA_21 PF13304.6 ORY48998.1 - 5e-08 33.1 1.6 0.0019 18.1 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORY48998.1 - 0.00015 21.7 0.1 0.00033 20.6 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 ORY48998.1 - 0.00017 21.3 0.2 0.00049 19.8 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 ORY48998.1 - 0.0036 16.8 0.0 0.034 13.6 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORY48998.1 - 0.0055 17.2 0.1 0.0099 16.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ORY48998.1 - 0.0079 15.8 0.4 0.28 10.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORY48998.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY48998.1 - 0.041 14.3 0.0 0.068 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 ORY48998.1 - 0.11 13.0 0.0 0.68 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 ORY48998.1 - 0.14 12.2 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DEAD PF00270.29 ORY48999.1 - 7e-45 152.9 0.0 1.8e-44 151.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY48999.1 - 1.6e-27 96.1 0.1 1.4e-26 93.0 0.0 2.5 1 1 2 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY48999.1 - 0.00085 19.4 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 ORY48999.1 - 0.01 15.2 0.1 0.018 14.4 0.1 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 ORY48999.1 - 0.039 12.7 0.1 2.8 6.6 0.1 2.5 2 1 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 ORY48999.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase NAD_binding_1 PF00175.21 ORY49000.1 - 1.8e-28 99.4 0.0 2.8e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ORY49000.1 - 6.2e-22 77.8 0.0 1.2e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 ORY49000.1 - 8.7e-05 22.7 0.0 0.0019 18.3 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DLH PF01738.18 ORY49001.1 - 1e-22 80.7 0.0 1.2e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 ORY49001.1 - 0.0049 16.5 0.0 0.011 15.4 0.0 1.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 ORY49001.1 - 0.044 13.7 0.0 0.094 12.6 0.0 1.5 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2048 PF09752.9 ORY49001.1 - 0.2 10.7 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 DUF2019 PF09450.10 ORY49001.1 - 0.21 11.5 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) Na_H_Exchanger PF00999.21 ORY49002.1 - 1.9e-53 181.6 26.6 2.4e-53 181.3 26.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 ORY49002.1 - 0.025 14.6 0.3 0.17 12.0 0.1 2.5 2 0 0 2 2 2 0 YrhC-like protein DUF4190 PF13828.6 ORY49002.1 - 0.23 11.2 0.0 0.23 11.2 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4190) Na_H_Exchanger PF00999.21 ORY49003.1 - 2.5e-52 177.9 33.9 3e-52 177.7 33.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YwcE PF17368.2 ORY49003.1 - 0.0011 19.6 1.5 0.0067 17.1 0.2 2.9 2 0 0 2 2 2 1 Spore morphogenesis and germination YwcE YrhC PF14143.6 ORY49003.1 - 0.04 14.0 0.1 0.04 14.0 0.1 3.2 4 0 0 4 4 4 0 YrhC-like protein YtpI PF14007.6 ORY49003.1 - 2.5 8.3 9.7 2.5 8.3 1.4 2.9 2 0 0 2 2 2 0 YtpI-like protein MpPF26 PF07666.11 ORY49003.1 - 8.8 6.5 13.0 4.8 7.3 2.3 3.8 4 0 0 4 4 4 0 M penetrans paralogue family 26 Na_H_Exchanger PF00999.21 ORY49004.1 - 5e-58 196.7 28.3 6.3e-58 196.4 28.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family MMM1 PF10296.9 ORY49006.1 - 4.2e-08 32.6 0.0 8.9e-08 31.5 0.0 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 GOLD_2 PF13897.6 ORY49006.1 - 0.68 10.4 4.4 15 6.1 0.0 4.3 6 0 0 6 6 6 0 Golgi-dynamics membrane-trafficking MMR_HSR1 PF01926.23 ORY49007.1 - 8.6e-16 58.0 0.1 2.2e-14 53.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY49007.1 - 5.7e-07 29.2 0.3 3.3e-05 23.5 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ORY49007.1 - 7.9e-07 29.1 0.1 0.00018 21.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 ORY49007.1 - 4.2e-05 23.7 0.2 0.013 15.5 0.2 3.1 2 1 0 2 2 2 2 Dynamin family ABC1 PF03109.16 ORY49008.1 - 1.1e-18 67.6 0.0 1.1e-13 51.4 0.0 2.3 2 0 0 2 2 2 2 ABC1 family zf-C2H2 PF00096.26 ORY49009.1 - 0.011 16.2 0.9 0.026 15.0 0.0 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type Acetyltransf_2 PF00797.17 ORY49011.1 - 4.6e-26 92.1 0.0 2.3e-25 89.8 0.0 1.9 1 1 0 1 1 1 1 N-acetyltransferase Scm3 PF10384.9 ORY49012.1 - 1.6e-14 53.3 0.2 1.6e-14 53.3 0.2 1.8 2 0 0 2 2 1 1 Centromere protein Scm3 BUD22 PF09073.10 ORY49012.1 - 0.042 13.2 3.8 0.054 12.8 3.8 1.2 1 0 0 1 1 1 0 BUD22 Sigma70_ner PF04546.13 ORY49012.1 - 0.38 10.6 4.8 0.57 10.0 4.8 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.12 ORY49012.1 - 0.45 8.7 7.7 0.55 8.4 7.7 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 ORY49012.1 - 0.52 10.0 7.0 0.73 9.5 7.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 ORY49012.1 - 0.9 8.6 13.7 1.5 7.9 13.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 ORY49012.1 - 1.7 7.9 11.5 2.3 7.5 11.5 1.2 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 ORY49012.1 - 1.8 6.8 3.2 2.3 6.4 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.13 ORY49012.1 - 2.1 8.3 9.6 0.53 10.2 4.5 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RXT2_N PF08595.11 ORY49012.1 - 4.4 7.3 6.8 9.4 6.2 6.8 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal CENP-B_dimeris PF09026.10 ORY49012.1 - 6.2 7.3 17.3 1 9.8 13.2 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 ORY49012.1 - 6.8 4.7 14.4 9.5 4.2 14.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi U1snRNP70_N PF12220.8 ORY49013.1 - 6.7e-22 77.9 0.3 9.6e-22 77.5 0.3 1.2 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 ORY49013.1 - 2.4e-16 59.3 0.0 4.1e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY49013.1 - 0.0033 17.5 0.0 0.0053 16.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif BolA PF01722.18 ORY49014.1 - 1.1e-29 102.5 1.0 1.3e-29 102.3 1.0 1.1 1 0 0 1 1 1 1 BolA-like protein Lectin_like PF18560.1 ORY49014.1 - 0.1 12.8 0.0 0.12 12.6 0.0 1.1 1 0 0 1 1 1 0 Lectin like domain zf-C4H2 PF10146.9 ORY49015.1 - 6e-09 36.5 3.3 7.3e-09 36.2 3.3 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein Snf7 PF03357.21 ORY49016.1 - 2.6e-35 121.6 12.5 3e-35 121.3 12.5 1.0 1 0 0 1 1 1 1 Snf7 PI_PP_I PF18363.1 ORY49016.1 - 0.067 13.4 2.2 0.19 11.9 0.5 2.1 1 1 1 2 2 2 0 Phosphoinositide phosphatase insertion domain Prefoldin_2 PF01920.20 ORY49016.1 - 2.5 8.1 11.7 4.6 7.2 2.7 2.7 2 1 0 2 2 2 0 Prefoldin subunit ALS_ss_C PF10369.9 ORY49017.1 - 6.9e-20 71.0 0.0 2.2e-17 63.0 0.0 2.6 2 0 0 2 2 2 2 Small subunit of acetolactate synthase ACT PF01842.25 ORY49017.1 - 1.4e-11 44.0 0.2 2.3e-11 43.3 0.2 1.4 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 ORY49017.1 - 9.9e-08 31.7 0.0 1.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 ORY49017.1 - 0.05 14.2 0.1 0.13 12.8 0.1 1.7 1 0 0 1 1 1 0 ACT domain IlvN PF07991.12 ORY49018.1 - 1.4e-43 148.3 0.0 2.2e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 ORY49018.1 - 2.8e-41 141.2 0.0 3.9e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 ORY49018.1 - 0.012 15.8 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IQ PF00612.27 ORY49019.1 - 7e-16 56.5 7.3 1.2e-05 24.7 0.1 3.5 3 0 0 3 3 3 3 IQ calmodulin-binding motif Svf1_C PF17187.4 ORY49021.1 - 2.5e-32 112.0 0.3 5.8e-32 110.8 0.0 1.7 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 ORY49021.1 - 4.7e-26 91.8 0.6 7.5e-26 91.1 0.6 1.3 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Sulfate_transp PF00916.20 ORY49022.1 - 7.9e-95 317.8 23.1 1.3e-93 313.8 23.1 2.1 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORY49022.1 - 1.3e-18 66.8 0.0 2.9e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 ORY49022.1 - 0.02 15.2 0.2 0.065 13.6 0.0 2.0 2 0 0 2 2 2 0 STAS domain MFS_MOT1 PF16983.5 ORY49022.1 - 0.38 11.2 15.1 0.041 14.3 4.5 3.0 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily Vfa1 PF08432.10 ORY49024.1 - 9.5e-16 58.6 1.3 6.6e-15 55.9 0.4 2.0 1 1 1 2 2 2 1 AAA-ATPase Vps4-associated protein 1 Prim_Zn_Ribbon PF08273.12 ORY49024.1 - 0.051 13.9 2.3 0.056 13.7 0.3 2.0 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase MFAP1 PF06991.11 ORY49025.1 - 3.8e-73 245.9 21.6 3.8e-73 245.9 21.6 2.6 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing DnaJ PF00226.31 ORY49026.1 - 1.5e-25 89.1 1.3 2.4e-25 88.4 1.3 1.4 1 0 0 1 1 1 1 DnaJ domain Tmemb_185A PF10269.9 ORY49026.1 - 7.5e-16 58.6 9.3 1.3e-15 57.7 9.3 1.5 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein Gaa1 PF04114.14 ORY49026.1 - 1.3 7.9 9.3 4.3 6.2 2.1 2.3 2 0 0 2 2 2 0 Gaa1-like, GPI transamidase component UPF0182 PF03699.13 ORY49026.1 - 2.2 6.3 5.0 2.9 5.9 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0182) ABC_tran PF00005.27 ORY49027.1 - 2.6e-51 173.7 0.0 1.8e-28 99.7 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ORY49027.1 - 2.9e-17 63.5 3.7 3.3e-06 27.2 0.3 4.2 2 2 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY49027.1 - 2.3e-10 40.3 0.0 0.012 15.1 0.0 4.0 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.24 ORY49027.1 - 4.5e-09 36.1 1.1 1e-08 34.9 1.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 ORY49027.1 - 4.6e-08 33.8 2.1 0.0053 17.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 ORY49027.1 - 4e-07 29.7 1.2 0.031 14.0 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY49027.1 - 1.5e-06 28.2 0.1 0.011 15.8 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 ORY49027.1 - 1.5e-05 24.9 2.2 0.28 10.9 0.5 3.4 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORY49027.1 - 1.8e-05 24.7 0.3 0.034 14.0 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase HEAT PF02985.22 ORY49027.1 - 3.8e-05 23.6 9.0 0.12 12.7 0.0 5.6 5 1 0 5 5 4 1 HEAT repeat MeaB PF03308.16 ORY49027.1 - 8.2e-05 21.7 0.7 0.049 12.6 0.0 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 ORY49027.1 - 0.00013 22.2 0.0 0.18 12.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORY49027.1 - 0.00027 21.2 0.1 0.42 10.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 ORY49027.1 - 0.00043 20.8 0.0 1.5 9.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 ORY49027.1 - 0.00081 19.6 0.1 2.2 8.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain DUF87 PF01935.17 ORY49027.1 - 0.001 19.2 4.1 0.028 14.5 0.3 3.1 3 0 0 3 3 3 1 Helicase HerA, central domain DUF815 PF05673.13 ORY49027.1 - 0.0013 18.0 0.2 0.28 10.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) CLASP_N PF12348.8 ORY49027.1 - 0.0031 17.1 0.0 0.12 11.9 0.0 3.0 4 0 0 4 4 4 1 CLASP N terminal AAA_27 PF13514.6 ORY49027.1 - 0.0041 16.7 0.0 0.81 9.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ORY49027.1 - 0.0076 16.6 0.5 6.3 7.2 0.0 3.0 3 0 0 3 3 2 0 RNA helicase Dynamin_N PF00350.23 ORY49027.1 - 0.008 16.2 0.2 1.1 9.3 0.0 3.1 3 0 0 3 3 3 1 Dynamin family AAA_30 PF13604.6 ORY49027.1 - 0.015 15.1 0.3 7.1 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ORY49027.1 - 0.015 15.7 0.0 2.6 8.4 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 ORY49027.1 - 0.018 14.3 0.6 4 6.6 0.1 2.8 3 0 0 3 3 3 0 Zeta toxin NACHT PF05729.12 ORY49027.1 - 0.021 14.8 3.7 2.2 8.2 0.1 3.3 3 1 0 3 3 3 0 NACHT domain Adaptin_N PF01602.20 ORY49027.1 - 0.04 12.5 0.6 0.16 10.5 0.3 1.9 1 1 1 2 2 2 0 Adaptin N terminal region Roc PF08477.13 ORY49027.1 - 0.043 14.0 0.3 15 5.8 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 ORY49027.1 - 0.044 13.5 0.4 3.9 7.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 ORY49027.1 - 0.093 13.2 0.0 40 4.6 0.0 3.2 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) DUF234 PF03008.14 ORY49027.1 - 0.099 13.1 0.8 0.73 10.3 0.9 2.3 2 0 0 2 2 2 0 Archaea bacterial proteins of unknown function HEAT_2 PF13646.6 ORY49027.1 - 0.1 13.0 8.7 0.99 9.8 0.1 4.4 3 2 1 4 4 4 0 HEAT repeats ATP-synt_ab PF00006.25 ORY49027.1 - 0.11 12.2 0.5 6 6.5 0.0 2.8 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 ORY49027.1 - 0.11 12.7 0.0 2.4 8.5 0.0 2.9 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 ORY49027.1 - 0.11 11.1 2.5 2.7 6.5 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 ORY49027.1 - 0.12 11.9 0.2 9.1 5.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 ORY49027.1 - 0.14 11.8 0.6 22 4.6 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Dopey_N PF04118.14 ORY49027.1 - 0.17 11.0 0.0 1.1 8.2 0.0 2.0 1 1 0 1 1 1 0 Dopey, N-terminal NB-ARC PF00931.22 ORY49027.1 - 0.19 10.9 0.6 12 5.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain MukB PF04310.12 ORY49027.1 - 0.22 11.3 0.5 3.6 7.3 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal ABC_tran_Xtn PF12848.7 ORY49027.1 - 9.7 6.3 7.8 1 9.4 0.3 2.5 2 0 0 2 2 2 0 ABC transporter GDP_Man_Dehyd PF16363.5 ORY49028.1 - 7.5e-75 252.4 0.0 1.2e-74 251.7 0.0 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY49028.1 - 3.3e-58 197.0 0.1 4e-58 196.7 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY49028.1 - 1.7e-24 86.3 0.0 2.1e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ORY49028.1 - 6.4e-22 78.0 0.0 7.1e-21 74.6 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 ORY49028.1 - 2.1e-19 69.7 0.3 7.2e-18 64.7 0.3 2.4 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 ORY49028.1 - 6.1e-17 61.6 0.0 1.1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 ORY49028.1 - 1.9e-06 27.9 0.0 5.4e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Inositol_P PF00459.25 ORY49029.1 - 1.2e-56 192.3 0.1 1.6e-56 191.8 0.1 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family DUF4611 PF15387.6 ORY49029.1 - 0.26 11.5 3.8 0.35 11.1 0.9 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Inositol_P PF00459.25 ORY49030.1 - 7e-53 179.9 0.0 1.2e-52 179.1 0.0 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family G_glu_transpept PF01019.21 ORY49031.1 - 6.8e-174 579.4 0.0 7.8e-174 579.2 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase DHC_N2 PF08393.13 ORY49032.1 - 8.5e-121 403.8 16.6 6.5e-87 292.2 4.9 3.9 3 1 1 4 4 4 2 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 ORY49032.1 - 8.2e-102 340.0 0.3 5.8e-101 337.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 ORY49032.1 - 3.4e-101 338.5 0.1 1.2e-100 336.8 0.1 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 ORY49032.1 - 1.3e-84 282.7 0.2 1.4e-83 279.4 0.5 2.8 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_6 PF12774.7 ORY49032.1 - 6.3e-84 281.7 11.0 3.3e-69 233.3 6.9 6.7 4 1 1 5 5 5 2 Hydrolytic ATP binding site of dynein motor region AAA_7 PF12775.7 ORY49032.1 - 4.7e-77 257.6 0.1 2.5e-72 242.2 0.0 3.5 3 0 0 3 3 3 2 P-loop containing dynein motor region Dynein_heavy PF03028.15 ORY49032.1 - 1.7e-44 150.7 0.0 2.1e-42 144.0 0.0 3.5 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 ORY49032.1 - 3.4e-39 134.3 3.6 5e-38 130.5 1.1 3.3 2 1 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 ORY49032.1 - 6.7e-38 130.6 6.0 1.4e-37 129.6 6.0 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 ORY49032.1 - 1.2e-34 119.1 0.0 8.8e-34 116.4 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 ORY49032.1 - 2.8e-19 69.2 0.2 1.4e-18 66.9 0.2 2.3 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 ORY49032.1 - 6e-11 42.5 0.0 0.012 15.6 0.0 5.4 4 2 0 4 4 4 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 ORY49032.1 - 2.2e-05 24.8 0.4 1.8 9.0 0.0 4.5 4 0 0 4 4 3 2 RNA helicase AAA_22 PF13401.6 ORY49032.1 - 0.00015 22.1 3.7 3.2 8.0 0.3 4.4 4 0 0 4 4 3 2 AAA domain AAA PF00004.29 ORY49032.1 - 0.00034 21.0 2.2 7 7.1 0.2 4.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY49032.1 - 0.0018 18.7 1.0 13 6.1 0.0 4.7 5 0 0 5 5 3 0 AAA ATPase domain AAA_18 PF13238.6 ORY49032.1 - 0.0038 17.8 0.2 2.3 8.8 0.0 4.1 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 ORY49032.1 - 0.02 13.9 2.7 2.9 6.9 0.2 3.0 3 0 0 3 3 3 0 Type II/IV secretion system protein DUF853 PF05872.12 ORY49032.1 - 0.17 10.5 6.7 1.4 7.4 0.0 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) Rad17 PF03215.15 ORY49032.1 - 0.18 11.7 1.5 33 4.3 0.1 3.7 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_30 PF13604.6 ORY49032.1 - 0.18 11.5 8.4 3.2 7.4 0.4 4.0 4 0 0 4 4 4 0 AAA domain CENP-Q PF13094.6 ORY49032.1 - 0.18 12.0 6.0 0.68 10.1 0.2 2.8 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Mg_chelatase PF01078.21 ORY49032.1 - 0.25 10.7 5.9 0.33 10.3 0.0 3.9 6 0 0 6 6 6 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 ORY49032.1 - 0.56 9.5 5.6 4.9 6.4 0.0 3.7 5 0 0 5 5 4 0 FtsK/SpoIIIE family Baculo_PEP_C PF04513.12 ORY49032.1 - 1.3 9.1 5.1 8.6 6.4 0.1 4.1 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TFIIS_M PF07500.14 ORY49033.1 - 1.1e-19 71.0 0.7 1.8e-19 70.3 0.7 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 ORY49033.1 - 2.2e-19 69.0 9.5 3.8e-19 68.3 9.5 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) XRN_M PF17846.1 ORY49033.1 - 0.085 11.8 0.6 0.13 11.2 0.6 1.2 1 0 0 1 1 1 0 Xrn1 helical domain zinc_ribbon_4 PF13717.6 ORY49033.1 - 0.15 12.0 3.1 1.9 8.5 0.3 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Baculo_LEF5_C PF11792.8 ORY49033.1 - 0.28 10.9 1.2 0.63 9.8 0.1 2.0 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain TF_Zn_Ribbon PF08271.12 ORY49033.1 - 0.33 10.5 3.5 1.1 8.9 3.4 1.9 1 1 1 2 2 2 0 TFIIB zinc-binding Acyl-CoA_dh_1 PF00441.24 ORY49034.1 - 1.3e-32 113.1 0.0 2.3e-32 112.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY49034.1 - 7.1e-21 74.2 0.4 1.3e-20 73.3 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 ORY49034.1 - 1e-19 70.4 0.0 2.5e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 ORY49034.1 - 5.7e-14 52.7 0.1 1.8e-13 51.1 0.1 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY49034.1 - 9.6e-06 25.9 0.0 1.9e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ribonucleas_3_3 PF14622.6 ORY49035.1 - 8.7e-19 68.0 0.0 3.6e-18 66.0 0.0 1.8 1 1 1 2 2 2 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 ORY49035.1 - 2.6e-15 56.9 0.3 1.6e-14 54.4 0.3 2.2 2 1 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.26 ORY49035.1 - 1.6e-10 41.6 0.0 2.5e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 ORY49035.1 - 7.3e-06 26.2 0.0 1.3e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_12 PF13087.6 ORY49037.1 - 1.3e-15 57.6 0.5 4.9e-15 55.7 0.5 2.0 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 ORY49037.1 - 4.6e-14 52.8 0.1 4e-06 26.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 ORY49037.1 - 2.5e-08 33.9 0.0 6.4e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY49037.1 - 3.2e-07 30.8 0.0 7.8e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 ORY49037.1 - 1.2e-05 25.3 0.0 0.00011 22.2 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 ORY49037.1 - 0.00017 21.5 0.0 0.00033 20.5 0.0 1.4 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 ORY49037.1 - 0.00042 19.9 0.0 0.0012 18.5 0.0 1.7 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 ORY49037.1 - 0.0079 16.0 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 ORY49037.1 - 0.17 11.3 0.0 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein CPSase_L_D2 PF02786.17 ORY49038.1 - 2.4e-53 180.8 0.1 4.6e-49 166.8 0.1 2.3 1 1 1 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ORY49038.1 - 5.4e-46 155.7 0.1 1.5e-45 154.2 0.1 1.8 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORY49038.1 - 1.3e-19 70.3 0.0 2.9e-18 66.0 0.0 3.0 2 2 1 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 ORY49038.1 - 4.5e-17 61.6 5.2 1.1e-16 60.4 3.7 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp PF02222.22 ORY49038.1 - 3.2e-06 26.8 0.1 3.3e-05 23.5 0.1 2.2 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ORY49038.1 - 3.8e-06 26.6 0.0 6.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 ORY49038.1 - 0.00053 19.8 4.2 0.0023 17.7 0.0 2.8 2 1 1 3 3 3 1 Biotin-lipoyl like GARS_A PF01071.19 ORY49038.1 - 0.00099 18.9 0.1 0.0017 18.2 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 ORY49038.1 - 0.0064 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp HlyD_3 PF13437.6 ORY49038.1 - 0.0077 16.9 0.1 2.5 8.9 0.1 2.7 2 0 0 2 2 2 1 HlyD family secretion protein NQRA PF05896.11 ORY49038.1 - 0.016 14.7 0.2 0.037 13.5 0.2 1.5 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) ATP-grasp_3 PF02655.14 ORY49038.1 - 0.024 14.7 0.0 0.057 13.5 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain RnfC_N PF13375.6 ORY49038.1 - 0.074 13.0 0.7 0.25 11.3 0.7 1.9 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain ATP-grasp_4 PF13535.6 ORY49038.1 - 0.099 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain HlyD_D23 PF16576.5 ORY49038.1 - 0.12 11.6 0.2 3.7 6.7 0.0 2.3 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion DUF3395 PF11875.8 ORY49039.1 - 3.2e-46 157.1 2.1 9.4e-46 155.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 ORY49039.1 - 7.8e-21 74.0 2.4 1.5e-20 73.0 2.4 1.5 1 0 0 1 1 1 1 DnaJ domain DUF4407 PF14362.6 ORY49039.1 - 0.47 9.8 11.6 1.1 8.6 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) MEA1 PF06910.11 ORY49040.1 - 1.9e-06 28.5 13.1 1.2e-05 26.0 11.7 2.9 1 1 0 1 1 1 1 Male enhanced antigen 1 (MEA1) BUD22 PF09073.10 ORY49040.1 - 2.5 7.3 13.5 3.3 6.9 13.5 1.2 1 0 0 1 1 1 0 BUD22 zf-C3HC4_2 PF13923.6 ORY49041.1 - 3.4e-07 30.0 13.9 5.4e-07 29.3 13.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY49041.1 - 1e-06 28.9 13.5 1.6e-06 28.3 13.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORY49041.1 - 1.9e-05 24.5 12.5 3.1e-05 23.8 12.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY49041.1 - 0.00012 21.9 14.3 0.00019 21.2 14.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY49041.1 - 0.018 15.3 13.6 0.094 13.0 13.6 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ORY49041.1 - 0.034 14.2 10.1 0.063 13.3 10.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger ANAPC_CDC26 PF10471.9 ORY49041.1 - 0.036 14.9 3.8 1.8 9.5 0.7 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 ZapB PF06005.12 ORY49041.1 - 0.14 12.6 16.3 0.8 10.2 0.4 3.2 3 0 0 3 3 3 0 Cell division protein ZapB TSC22 PF01166.18 ORY49041.1 - 0.17 12.2 12.2 1.9 8.8 0.5 3.3 3 0 0 3 3 3 0 TSC-22/dip/bun family Mto2_bdg PF12808.7 ORY49041.1 - 0.24 11.7 0.3 0.24 11.7 0.3 2.8 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF1272 PF06906.11 ORY49041.1 - 0.35 11.0 6.2 0.63 10.2 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_5 PF14634.6 ORY49041.1 - 0.41 10.6 12.1 0.75 9.8 12.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DivIC PF04977.15 ORY49041.1 - 0.44 10.3 14.0 1.3 8.9 1.2 3.3 3 0 0 3 3 3 0 Septum formation initiator bZIP_2 PF07716.15 ORY49041.1 - 0.93 9.6 18.4 4.1 7.6 4.3 3.3 3 0 0 3 3 3 0 Basic region leucine zipper GTP-bdg_M PF16360.5 ORY49041.1 - 1 10.0 7.3 0.37 11.4 1.9 2.4 2 1 0 2 2 2 0 GTP-binding GTPase Middle Region zf-P11 PF03854.14 ORY49041.1 - 1.1 9.0 14.8 3.4 7.4 13.0 2.2 1 1 1 2 2 2 0 P-11 zinc finger CASP_C PF08172.12 ORY49041.1 - 1.4 8.2 12.2 0.32 10.3 2.2 2.1 2 0 0 2 2 2 0 CASP C terminal Prok-RING_4 PF14447.6 ORY49041.1 - 3.5 7.6 11.3 6 6.8 11.3 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Cnn_1N PF07989.11 ORY49041.1 - 4 7.7 9.3 2.4 8.4 0.6 3.1 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 DUF4140 PF13600.6 ORY49041.1 - 5.4 7.5 8.7 2.3 8.7 0.4 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) zf-C3HC4_4 PF15227.6 ORY49041.1 - 6.8 6.9 11.9 12 6.1 11.9 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING GST_C_3 PF14497.6 ORY49042.1 - 1.3e-16 60.6 0.0 3e-16 59.4 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY49042.1 - 4.7e-08 33.3 0.0 1.3e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY49042.1 - 2.8e-05 24.3 0.0 8.3e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY49042.1 - 0.00017 21.9 0.0 0.00049 20.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY49042.1 - 0.0012 19.0 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 ORY49042.1 - 0.0058 16.9 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 ORY49042.1 - 0.0082 16.1 0.1 0.019 15.0 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY49043.1 - 3.8e-17 62.3 0.0 8.3e-17 61.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY49043.1 - 1.7e-06 28.3 0.0 4.4e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY49043.1 - 1.5e-05 25.2 0.0 3.1e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY49043.1 - 9.8e-05 22.7 0.0 0.00022 21.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY49043.1 - 0.00023 21.3 0.0 0.00037 20.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 ORY49043.1 - 0.00062 20.1 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 ORY49043.1 - 0.015 15.3 0.0 0.037 14.0 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CbiN PF02553.15 ORY49043.1 - 0.058 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Cobalt transport protein component CbiN GST_C_3 PF14497.6 ORY49044.1 - 2.6e-17 62.8 0.0 6.2e-17 61.6 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY49044.1 - 1.3e-07 31.8 0.0 3.2e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY49044.1 - 3.2e-05 24.1 0.0 9.4e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY49044.1 - 0.00024 21.5 0.0 0.00081 19.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY49044.1 - 0.00027 21.1 0.0 0.00037 20.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 ORY49044.1 - 0.006 16.9 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 ORY49044.1 - 0.019 15.0 0.0 0.045 13.8 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ank_3 PF13606.6 ORY49045.1 - 2.3e-13 49.0 0.2 0.00011 22.4 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 ORY49045.1 - 3.3e-13 50.0 0.0 3.9e-05 24.2 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ion_trans PF00520.31 ORY49045.1 - 5.7e-12 45.4 9.7 7.7e-12 45.0 9.7 1.2 1 0 0 1 1 1 1 Ion transport protein Ank_4 PF13637.6 ORY49045.1 - 2.2e-10 40.8 0.0 0.0016 19.0 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY49045.1 - 7.9e-10 38.7 0.1 0.00054 20.3 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 ORY49045.1 - 1.3e-07 31.7 0.3 0.14 12.6 0.1 4.5 4 1 0 4 4 4 2 Ankyrin repeats (many copies) PKD_channel PF08016.12 ORY49045.1 - 0.001 17.8 0.1 0.0023 16.7 0.1 1.5 1 0 0 1 1 1 1 Polycystin cation channel Acyl-CoA_dh_1 PF00441.24 ORY49046.1 - 1.2e-31 109.9 0.0 2.1e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 ORY49046.1 - 1e-19 70.4 0.0 2.5e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 ORY49046.1 - 5.8e-19 68.1 0.1 1.1e-18 67.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 ORY49046.1 - 9.5e-16 58.5 0.0 2.7e-15 57.0 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY49046.1 - 0.00023 21.4 0.0 0.00046 20.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain GDA1_CD39 PF01150.17 ORY49047.1 - 2.3e-92 309.9 0.0 3.2e-92 309.4 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Guanylate_cyc_2 PF09778.9 ORY49050.1 - 2.8e-51 173.9 0.0 1.2e-37 129.3 0.0 2.2 2 0 0 2 2 2 2 Guanylylate cyclase Peptidase_C39_2 PF13529.6 ORY49050.1 - 0.00018 22.1 0.9 0.14 12.7 0.0 3.0 3 0 0 3 3 3 2 Peptidase_C39 like family FAM220 PF15487.6 ORY49050.1 - 0.0054 16.4 3.9 0.011 15.4 3.9 1.4 1 0 0 1 1 1 1 FAM220 family Peptidase_C39 PF03412.15 ORY49050.1 - 0.0082 15.9 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase C39 family Peptidase_C70 PF12385.8 ORY49050.1 - 0.015 15.3 0.0 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 Papain-like cysteine protease AvrRpt2 Acyltransferase PF01553.21 ORY49051.1 - 1.9e-16 59.9 0.0 3.6e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 ORY49051.1 - 3e-07 30.4 0.5 0.00059 19.9 0.0 2.6 2 0 0 2 2 2 2 Acyltransferase C-terminus NAD_binding_6 PF08030.12 ORY49052.1 - 4.9e-35 121.0 0.0 9.3e-35 120.1 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 ORY49052.1 - 2.2e-19 69.8 9.8 2.2e-19 69.8 9.8 1.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ORY49052.1 - 1.1e-17 64.1 0.0 2.2e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 ORY49052.1 - 0.057 14.1 0.0 0.14 12.8 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF1899 PF08953.11 ORY49053.1 - 2.3e-32 110.7 0.4 6.9e-32 109.1 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 ORY49053.1 - 2.8e-19 68.7 0.3 5.7e-19 67.7 0.3 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 ORY49053.1 - 6.7e-16 58.4 1.9 0.00061 20.5 0.0 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY49053.1 - 1.4e-06 28.5 0.3 0.001 19.3 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain SHE3 PF17078.5 ORY49053.1 - 9.1e-05 22.3 0.6 0.00013 21.8 0.6 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Nup160 PF11715.8 ORY49053.1 - 0.00042 19.1 0.1 0.36 9.4 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF4686 PF15742.5 ORY49053.1 - 0.019 14.1 2.7 0.025 13.7 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4686) Sec2p PF06428.11 ORY49053.1 - 0.027 14.4 4.0 0.043 13.8 4.0 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Cnn_1N PF07989.11 ORY49053.1 - 0.054 13.6 1.3 0.1 12.8 1.3 1.3 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 PQQ_2 PF13360.6 ORY49053.1 - 0.088 12.4 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 PQQ-like domain DUF5046 PF16465.5 ORY49053.1 - 0.13 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5046) PKcGMP_CC PF16808.5 ORY49053.1 - 0.13 12.1 0.5 0.25 11.2 0.3 1.6 1 1 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase ZapB PF06005.12 ORY49053.1 - 0.18 12.3 5.1 0.3 11.5 5.1 1.3 1 0 0 1 1 1 0 Cell division protein ZapB Shugoshin_N PF07558.11 ORY49053.1 - 0.18 11.7 1.0 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region PQQ PF01011.21 ORY49053.1 - 0.2 11.6 1.0 1.1 9.3 0.0 2.8 3 0 0 3 3 3 0 PQQ enzyme repeat CCDC92 PF14916.6 ORY49053.1 - 0.22 11.3 0.8 0.43 10.4 0.8 1.5 1 0 0 1 1 1 0 Coiled-coil domain of unknown function NPV_P10 PF05531.12 ORY49053.1 - 0.84 10.1 3.0 1.5 9.3 3.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Csm1_N PF18504.1 ORY49053.1 - 1.3 9.4 7.3 0.17 12.2 2.6 1.9 2 0 0 2 2 2 0 Csm1 N-terminal domain DivIC PF04977.15 ORY49053.1 - 2.7 7.8 4.9 6.9 6.5 4.9 1.7 1 1 0 1 1 1 0 Septum formation initiator AAA PF00004.29 ORY49054.1 - 3.6e-43 147.2 0.0 7e-43 146.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 ORY49054.1 - 1.1e-24 86.2 0.6 6.3e-24 83.7 0.1 2.5 1 1 1 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 ORY49054.1 - 1.7e-23 82.5 8.0 4.3e-23 81.2 8.0 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 ORY49054.1 - 6.1e-06 26.0 0.0 3e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 ORY49054.1 - 7.3e-06 26.5 0.2 0.0016 18.9 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 ORY49054.1 - 9.4e-06 25.1 0.2 4.8e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 ORY49054.1 - 2e-05 24.6 0.0 0.00017 21.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ORY49054.1 - 5.3e-05 23.0 0.0 9.8e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 ORY49054.1 - 7.4e-05 22.5 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 ORY49054.1 - 0.00012 22.4 0.5 0.023 15.0 0.0 2.7 2 1 1 3 3 2 1 AAA domain DUF815 PF05673.13 ORY49054.1 - 0.00019 20.7 0.0 0.00082 18.6 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 ORY49054.1 - 0.00022 21.2 0.7 0.0017 18.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 ORY49054.1 - 0.00048 20.5 0.1 0.015 15.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_2 PF07724.14 ORY49054.1 - 0.0019 18.4 0.4 0.024 14.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 ORY49054.1 - 0.0019 18.3 0.0 0.0045 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY49054.1 - 0.002 18.7 0.0 0.0063 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 ORY49054.1 - 0.0032 17.2 0.6 0.01 15.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.17 ORY49054.1 - 0.0092 15.1 0.0 0.11 11.5 0.0 2.4 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 ORY49054.1 - 0.0098 15.5 0.1 0.7 9.4 0.1 2.4 1 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 ORY49054.1 - 0.03 14.8 0.1 0.11 12.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain TniB PF05621.11 ORY49054.1 - 0.032 13.7 0.0 4.8 6.5 0.0 2.5 1 1 0 2 2 2 0 Bacterial TniB protein Mg_chelatase PF01078.21 ORY49054.1 - 0.037 13.4 0.0 0.09 12.1 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 ORY49054.1 - 0.042 13.8 0.0 0.29 11.1 0.0 2.3 2 1 1 3 3 2 0 NACHT domain Sigma54_activat PF00158.26 ORY49054.1 - 0.077 12.7 0.0 0.42 10.3 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 ORY49054.1 - 0.082 12.2 0.0 5.6 6.2 0.0 2.5 1 1 1 2 2 2 0 KaiC PhoH PF02562.16 ORY49054.1 - 0.083 12.3 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein NRBF2_MIT PF17169.4 ORY49054.1 - 0.11 12.7 0.6 0.25 11.6 0.6 1.6 1 0 0 1 1 1 0 MIT domain of nuclear receptor-binding factor 2 Torsin PF06309.11 ORY49054.1 - 0.15 12.2 0.0 0.46 10.6 0.0 1.8 2 0 0 2 2 1 0 Torsin TarH PF02203.15 ORY49054.1 - 0.25 11.2 2.3 0.48 10.3 2.3 1.4 1 0 0 1 1 1 0 Tar ligand binding domain homologue USP8_dimer PF08969.11 ORY49054.1 - 0.3 11.3 9.3 0.71 10.1 9.3 1.6 1 0 0 1 1 1 0 USP8 dimerisation domain ATPase_2 PF01637.18 ORY49054.1 - 1.5 8.7 5.3 3 7.7 0.0 3.0 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea zf-H2C2_2 PF13465.6 ORY49056.1 - 1.7e-09 37.7 2.4 0.00029 21.1 0.5 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY49056.1 - 1.6e-08 34.5 7.1 0.00032 21.0 0.0 2.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY49056.1 - 7.7e-08 32.5 6.4 0.0039 17.9 0.1 2.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 ORY49056.1 - 0.0026 18.4 1.8 0.0031 18.2 0.2 1.7 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 ORY49056.1 - 0.0084 16.4 1.4 6.1 7.3 0.0 3.0 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zinc_ribbon_15 PF17032.5 ORY49056.1 - 0.011 16.5 0.6 0.012 16.3 0.6 1.1 1 0 0 1 1 1 0 zinc-ribbon family zf_C2H2_ZHX PF18387.1 ORY49056.1 - 0.011 15.4 0.7 1.9 8.2 0.1 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-AN1 PF01428.16 ORY49056.1 - 0.012 15.8 1.0 4 7.7 0.1 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger zf-C2H2_6 PF13912.6 ORY49056.1 - 0.022 14.8 6.1 1 9.4 0.2 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger RNA_POL_M_15KD PF02150.16 ORY49056.1 - 0.025 14.4 0.9 6.7 6.7 0.1 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit zf-UDP PF14569.6 ORY49056.1 - 0.046 13.8 0.6 0.066 13.3 0.6 1.3 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-met PF12874.7 ORY49056.1 - 0.09 13.2 2.1 18 5.9 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type gag_pre-integrs PF13976.6 ORY49056.1 - 0.12 12.2 1.2 7.6 6.5 0.1 2.0 1 1 1 2 2 2 0 GAG-pre-integrase domain zf-C2HE PF16278.5 ORY49056.1 - 0.13 12.7 4.7 1 9.9 0.3 2.4 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf_UBZ PF18439.1 ORY49056.1 - 0.16 11.6 2.4 1.5 8.5 0.4 2.3 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_3 PF13878.6 ORY49056.1 - 0.16 11.8 2.9 0.46 10.3 0.3 2.3 2 1 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO OrfB_Zn_ribbon PF07282.11 ORY49056.1 - 0.45 10.5 3.6 5 7.1 0.1 2.1 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Sel1 PF08238.12 ORY49057.1 - 6e-31 106.2 9.1 1.3e-06 28.9 0.0 7.9 8 0 0 8 8 8 6 Sel1 repeat Raptor_N PF14538.6 ORY49057.1 - 0.02 14.9 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain DUF3130 PF11328.8 ORY49057.1 - 0.083 13.1 0.1 0.28 11.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3130 TPR_16 PF13432.6 ORY49057.1 - 0.36 11.5 3.5 7.3 7.3 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY49057.1 - 1.4 9.7 7.4 20 6.1 0.0 5.1 6 1 0 6 6 6 0 Tetratricopeptide repeat F-box-like PF12937.7 ORY49058.1 - 0.00015 21.6 0.3 0.00044 20.1 0.3 1.8 1 0 0 1 1 1 1 F-box-like PRANC PF09372.10 ORY49058.1 - 0.051 13.9 0.5 0.17 12.2 0.0 2.0 3 0 0 3 3 3 0 PRANC domain W2 PF02020.18 ORY49059.1 - 3.9e-11 42.9 0.1 3.9e-11 42.9 0.1 2.3 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon APP_amyloid PF10515.9 ORY49059.1 - 0.27 11.7 0.8 0.94 10.0 0.8 1.9 1 0 0 1 1 1 0 Beta-amyloid precursor protein C-terminus DivIC PF04977.15 ORY49059.1 - 6.1 6.7 8.0 0.68 9.7 0.9 2.5 1 1 1 2 2 2 0 Septum formation initiator TFB6 PF17110.5 ORY49059.1 - 6.6 6.4 10.7 0.44 10.3 5.5 1.6 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH FtsJ PF01728.19 ORY49060.1 - 5.7e-29 101.5 0.0 8.3e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Apis_Csd PF11671.8 ORY49060.1 - 1.6 8.7 8.7 0.048 13.7 2.3 1.7 2 0 0 2 2 2 0 Complementary sex determiner protein WD40 PF00400.32 ORY49061.1 - 4.5e-50 166.5 32.6 8.2e-07 29.6 0.4 11.1 10 0 0 10 10 10 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY49061.1 - 9.2e-20 70.7 9.5 0.00031 21.0 0.0 8.7 6 3 3 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 ORY49061.1 - 1.5e-15 57.4 0.4 2.8e-15 56.5 0.4 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40_like PF17005.5 ORY49061.1 - 2.9e-09 36.7 0.0 0.0025 17.2 0.0 4.7 5 1 0 5 5 5 3 WD40-like domain Ge1_WD40 PF16529.5 ORY49061.1 - 2e-07 30.3 4.7 0.95 8.4 0.0 5.9 2 2 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORY49061.1 - 0.00015 20.6 0.3 0.64 8.6 0.0 4.2 4 1 0 4 4 4 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 ORY49061.1 - 0.0032 16.3 3.3 0.82 8.3 0.4 3.6 3 2 0 3 3 3 2 Nup133 N terminal like Frtz PF11768.8 ORY49061.1 - 0.012 13.9 0.0 0.45 8.8 0.0 2.8 2 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Utp13 PF08625.11 ORY49061.1 - 0.065 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain EF-hand_1 PF00036.32 ORY49062.1 - 5.5e-26 88.1 9.1 4.4e-08 32.1 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 ORY49062.1 - 2e-21 76.2 2.1 9.1e-13 48.5 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY49062.1 - 6.7e-20 69.3 1.2 1.2e-07 31.1 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 ORY49062.1 - 9e-20 70.3 7.3 5e-08 32.7 0.5 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 ORY49062.1 - 1.1e-14 53.2 6.9 7.5e-05 22.1 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 ORY49062.1 - 1.6e-06 28.0 0.5 0.35 10.8 0.0 3.2 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 ORY49062.1 - 0.001 19.4 0.0 0.067 13.5 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain Toprim_4 PF13662.6 ORY49062.1 - 0.0036 17.7 0.0 0.86 10.1 0.0 2.2 2 0 0 2 2 2 1 Toprim domain Epimerase PF01370.21 ORY49063.1 - 2.3e-38 132.0 0.0 6.2e-38 130.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY49063.1 - 1e-37 130.3 0.9 1.4e-26 93.7 1.0 2.9 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ORY49063.1 - 4.5e-09 35.7 0.1 5.7e-08 32.1 0.5 2.4 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 ORY49063.1 - 4.4e-05 22.8 0.6 0.00024 20.3 0.6 1.9 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 ORY49063.1 - 0.00011 21.5 0.0 0.00032 19.9 0.0 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 ORY49063.1 - 0.00095 18.4 0.9 0.043 12.9 1.0 2.7 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 ORY49063.1 - 0.094 12.6 1.2 0.56 10.1 1.2 2.1 1 1 0 1 1 1 0 KR domain CSN5_C PF18323.1 ORY49063.1 - 0.14 13.1 0.0 0.34 11.8 0.0 1.6 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain FAM183 PF14886.6 ORY49064.1 - 2.3e-22 79.8 0.5 3e-22 79.4 0.5 1.1 1 0 0 1 1 1 1 FAM183A and FAM183B related LLC1 PF14945.6 ORY49064.1 - 0.051 14.2 0.3 0.09 13.4 0.3 1.5 1 1 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein Sec7 PF01369.20 ORY49065.1 - 2.2e-62 210.0 0.6 5.1e-62 208.8 0.6 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 ORY49065.1 - 1.4e-34 119.3 1.0 6.1e-34 117.2 0.4 2.5 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 ORY49065.1 - 1.9e-27 94.9 0.4 1.9e-27 94.9 0.4 5.1 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) DCB PF16213.5 ORY49065.1 - 5.9e-18 65.1 8.5 8.5e-15 54.9 1.9 4.6 4 1 0 4 4 4 2 Dimerisation and cyclophilin-binding domain of Mon2 UNC45-central PF11701.8 ORY49065.1 - 3.6 7.5 6.4 3.5 7.6 0.4 3.3 3 0 0 3 3 3 0 Myosin-binding striated muscle assembly central TPR_14 PF13428.6 ORY49066.1 - 0.0023 18.6 0.0 0.46 11.4 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY49066.1 - 0.065 13.9 0.0 0.28 11.8 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY49067.1 - 0.0064 17.2 0.4 17 6.6 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 ORY49067.1 - 0.015 15.3 6.6 0.038 14.0 1.0 4.0 4 1 0 4 4 4 0 Mad3/BUB1 homology region 1 TPR_19 PF14559.6 ORY49067.1 - 0.1 13.1 0.0 0.97 10.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat 2-Hacid_dh_C PF02826.19 ORY49068.1 - 2.4e-43 147.6 0.1 7.4e-41 139.4 0.1 2.3 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY49068.1 - 3.1e-05 23.7 0.0 0.0093 15.6 0.0 2.1 1 1 1 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_7 PF13241.6 ORY49068.1 - 0.0054 17.2 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 ORY49068.1 - 0.02 15.0 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AAA PF00004.29 ORY49069.1 - 7.1e-16 58.8 0.0 9.6e-08 32.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY49069.1 - 0.00071 20.0 0.5 0.0019 18.6 0.5 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ORY49069.1 - 0.0016 18.5 0.0 0.014 15.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 ORY49069.1 - 0.0019 18.5 1.0 0.0058 17.0 0.0 2.3 3 0 0 3 3 3 1 RNA helicase Polyoma_lg_T_C PF06431.11 ORY49069.1 - 0.0071 15.3 0.2 0.017 14.0 0.0 1.7 2 0 0 2 2 2 1 Polyomavirus large T antigen C-terminus ABC_tran PF00005.27 ORY49069.1 - 0.0087 16.6 0.1 0.02 15.4 0.1 1.6 1 0 0 1 1 1 1 ABC transporter DUF815 PF05673.13 ORY49069.1 - 0.011 14.9 0.0 0.037 13.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 ORY49069.1 - 0.011 15.4 0.1 0.06 13.1 0.0 2.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain RuvB_N PF05496.12 ORY49069.1 - 0.034 13.9 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 ORY49069.1 - 0.035 13.6 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 ORY49069.1 - 0.037 14.6 0.3 0.14 12.7 0.3 2.1 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 ORY49069.1 - 0.064 12.5 1.4 0.062 12.5 0.3 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CDC45 PF02724.14 ORY49069.1 - 0.18 10.1 10.1 0.3 9.3 10.1 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF1682 PF07946.14 ORY49069.1 - 0.86 8.8 10.1 1.5 7.9 10.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) NARP1 PF12569.8 ORY49069.1 - 4.2 6.2 12.0 6.4 5.6 12.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 FAD_binding_2 PF00890.24 ORY49070.1 - 1.8e-74 251.3 2.9 2.6e-74 250.8 2.9 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY49070.1 - 1.8e-11 44.3 2.3 8.2e-11 42.1 2.3 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY49070.1 - 1.1e-09 38.3 0.7 2.5e-08 34.0 0.4 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY49070.1 - 1.1e-08 34.6 1.3 5.8e-08 32.3 1.2 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORY49070.1 - 1.8e-08 34.2 2.8 2.6e-08 33.7 1.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 ORY49070.1 - 9.4e-06 25.1 0.8 2.4e-05 23.7 0.2 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 ORY49070.1 - 1.7e-05 23.8 3.5 0.00017 20.4 1.6 2.8 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 ORY49070.1 - 1.8e-05 24.0 2.3 9.5e-05 21.6 1.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 ORY49070.1 - 2.7e-05 23.5 1.4 0.0099 15.1 0.5 2.6 2 0 0 2 2 2 2 Thi4 family Pyr_redox_3 PF13738.6 ORY49070.1 - 2.9e-05 23.5 0.1 0.0024 17.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY49070.1 - 0.00029 21.3 1.0 0.0064 17.0 0.8 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 ORY49070.1 - 0.0034 16.7 2.0 0.0064 15.8 1.4 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 ORY49070.1 - 0.005 17.3 0.1 0.018 15.4 0.0 2.0 2 0 0 2 2 2 1 Putative NAD(P)-binding MCRA PF06100.11 ORY49070.1 - 0.12 11.2 0.2 0.93 8.2 0.3 2.1 2 0 0 2 2 2 0 MCRA family Amino_oxidase PF01593.24 ORY49070.1 - 0.31 10.3 2.0 2.2 7.4 0.6 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase RNA_pol_A_bac PF01000.26 ORY49071.1 - 6.8e-34 116.6 0.1 1.1e-33 115.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 ORY49071.1 - 3.4e-19 68.0 0.0 4.1e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain 2OG-FeII_Oxy_2 PF13532.6 ORY49072.1 - 2.9e-08 34.1 0.0 3.5e-07 30.6 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily KIAA1430 PF13879.6 ORY49074.1 - 4.7e-16 59.4 11.0 4.7e-16 59.4 11.0 3.4 4 1 0 4 4 4 1 KIAA1430 homologue F-box-like PF12937.7 ORY49075.1 - 7.6e-05 22.5 0.1 0.00076 19.3 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY49075.1 - 0.076 12.9 1.2 0.47 10.4 0.0 2.9 3 0 0 3 3 3 0 F-box domain Aminotran_1_2 PF00155.21 ORY49076.1 - 5.2e-91 305.5 0.0 6e-91 305.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ANF_receptor PF01094.28 ORY49077.1 - 2.4e-11 43.3 0.0 4.4e-11 42.5 0.0 1.3 1 1 0 1 1 1 1 Receptor family ligand binding region Pkinase PF00069.25 ORY49078.1 - 1.9e-48 165.1 0.0 3.4e-48 164.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY49078.1 - 1.4e-13 50.8 0.0 4.6e-13 49.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Peptidase_M28 PF04389.17 ORY49078.1 - 0.067 12.9 0.4 0.13 12.0 0.4 1.4 1 0 0 1 1 1 0 Peptidase family M28 BRX_assoc PF16627.5 ORY49078.1 - 1.9 8.7 10.0 0.25 11.5 3.5 2.7 2 0 0 2 2 2 0 Unstructured region between BRX_N and BRX domain DUF2358 PF10184.9 ORY49079.1 - 0.027 14.7 0.0 5.9 7.2 0.0 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2358) AA_permease PF00324.21 ORY49080.1 - 2.5e-116 389.1 39.4 3.1e-116 388.8 39.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY49080.1 - 1.2e-36 126.5 41.4 1.4e-36 126.2 41.4 1.0 1 0 0 1 1 1 1 Amino acid permease NMO PF03060.15 ORY49081.1 - 2.3e-57 194.9 0.3 6.7e-56 190.1 0.3 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 ORY49081.1 - 1.1e-13 50.9 0.7 9.1e-07 28.2 0.0 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 ORY49081.1 - 0.006 15.6 0.2 0.011 14.8 0.1 1.5 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 ORY49081.1 - 0.019 14.1 1.0 0.048 12.8 1.0 1.7 1 1 0 1 1 1 0 Conserved region in glutamate synthase DUF1902 PF08972.11 ORY49081.1 - 0.029 14.3 0.6 0.5 10.4 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1902) His_biosynth PF00977.21 ORY49081.1 - 0.12 11.8 0.5 0.63 9.5 0.1 2.1 1 1 1 2 2 2 0 Histidine biosynthesis protein TMEM214 PF10151.9 ORY49082.1 - 0.06 11.8 2.4 0.072 11.5 2.4 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF4203 PF13886.6 ORY49084.1 - 2.4e-36 125.3 42.8 3.4e-36 124.8 42.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) Ycf66_N PF07444.11 ORY49084.1 - 0.0075 16.4 3.5 0.0075 16.4 3.5 2.9 4 1 0 4 4 4 1 Ycf66 protein N-terminus MGC-24 PF05283.11 ORY49084.1 - 0.21 12.0 1.4 0.43 11.0 1.4 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3088 PF11287.8 ORY49085.1 - 0.13 12.0 0.2 0.28 11.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) Syntaxin-6_N PF09177.11 ORY49085.1 - 0.68 10.5 5.9 1.7 9.2 5.9 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Zn_clus PF00172.18 ORY49086.1 - 2.3e-06 27.6 13.2 3.5e-06 27.0 13.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ketoacyl-synt PF00109.26 ORY49087.1 - 7.1e-55 186.3 0.0 1.4e-54 185.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 ORY49087.1 - 1.8e-46 159.1 0.0 3.8e-46 158.1 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Condensation PF00668.20 ORY49087.1 - 5.5e-39 134.1 0.3 8.3e-39 133.5 0.3 1.2 1 0 0 1 1 1 1 Condensation domain Ketoacyl-synt_C PF02801.22 ORY49087.1 - 3.3e-32 111.0 0.0 7.3e-32 109.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 ORY49087.1 - 6.1e-31 107.7 0.0 1.9e-30 106.1 0.0 1.9 2 0 0 2 2 1 1 KR domain PS-DH PF14765.6 ORY49087.1 - 1.1e-18 67.5 0.0 2.3e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 ORY49087.1 - 9.2e-13 48.8 0.0 2.7e-12 47.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 ORY49087.1 - 9.9e-10 38.6 0.4 9.9e-10 38.6 0.4 2.2 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 ORY49087.1 - 1.8e-08 34.4 0.0 3.7e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY49087.1 - 2.9e-08 33.6 0.0 2.9e-07 30.4 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 ORY49087.1 - 1.5e-07 31.9 0.0 3.7e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_11 PF08241.12 ORY49087.1 - 2.5e-05 24.8 0.0 8.7e-05 23.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain SAT PF16073.5 ORY49087.1 - 0.00031 20.6 0.9 0.0031 17.3 0.9 2.2 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_25 PF13649.6 ORY49087.1 - 0.00046 20.8 0.0 0.0022 18.7 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain ACP_syn_III PF08545.10 ORY49087.1 - 0.0072 16.2 0.1 0.033 14.0 0.1 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DREV PF05219.12 ORY49087.1 - 0.03 13.4 0.0 0.064 12.3 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase ADH_zinc_N_2 PF13602.6 ORY49087.1 - 0.037 15.1 0.0 0.12 13.5 0.0 2.0 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY49087.1 - 0.056 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 ORY49087.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Methyltransf_16 PF10294.9 ORY49087.1 - 0.14 11.9 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 Lysine methyltransferase Sin_N PF04801.13 ORY49088.1 - 2.3e-77 261.0 0.1 6e-72 243.2 0.2 2.1 2 0 0 2 2 2 2 Sin-like protein conserved region Pkinase PF00069.25 ORY49089.1 - 6.4e-05 22.4 0.0 8.7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain UBM PF14377.6 ORY49089.1 - 0.15 11.5 0.1 0.31 10.5 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin binding region Pkinase PF00069.25 ORY49090.1 - 3.2e-20 72.6 0.0 6.4e-20 71.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY49090.1 - 1.2e-06 28.0 0.0 1.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY49090.1 - 0.0012 18.3 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MPP6 PF10175.9 ORY49091.1 - 0.011 16.3 0.5 0.42 11.1 0.8 2.4 2 0 0 2 2 2 0 M-phase phosphoprotein 6 Mucin PF01456.17 ORY49091.1 - 0.037 14.0 15.4 0.069 13.1 15.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 ORY49091.1 - 0.1 12.5 6.9 0.22 11.5 6.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) NPR3 PF03666.13 ORY49091.1 - 0.19 10.5 0.8 0.3 9.8 0.8 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SSP160 PF06933.11 ORY49091.1 - 3.4 5.7 15.0 5.5 5.1 15.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Nucleo_P87 PF07267.11 ORY49091.1 - 4.6 6.0 6.9 0.076 11.9 0.2 1.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 RNA_pol_3_Rpc31 PF11705.8 ORY49091.1 - 5.4 7.2 21.0 0.1 12.8 12.9 1.9 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4636 PF15468.6 ORY49091.1 - 7.3 6.2 8.0 5 6.8 4.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4636) MIR PF02815.19 ORY49092.1 - 0.053 13.4 1.4 0.12 12.2 1.4 1.5 1 0 0 1 1 1 0 MIR domain Gtr1_RagA PF04670.12 ORY49094.1 - 0.094 12.1 0.0 0.094 12.1 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Gtr1_RagA PF04670.12 ORY49095.1 - 0.094 12.1 0.0 0.094 12.1 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Gtr1_RagA PF04670.12 ORY49096.1 - 0.094 12.1 0.0 0.094 12.1 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region LRR_4 PF12799.7 ORY49097.1 - 3.1e-17 62.4 35.4 0.00023 21.5 0.2 7.1 5 1 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY49097.1 - 3.2e-17 62.0 36.4 4.6e-05 23.1 1.6 6.4 4 2 2 6 6 6 6 Leucine rich repeat LRR_1 PF00560.33 ORY49097.1 - 4.7e-07 29.4 37.0 1.6 9.6 0.1 10.4 8 3 2 10 10 10 5 Leucine Rich Repeat F-box PF00646.33 ORY49097.1 - 0.013 15.4 0.1 0.029 14.3 0.1 1.6 1 0 0 1 1 1 0 F-box domain GalKase_gal_bdg PF10509.9 ORY49098.1 - 2.5e-23 81.4 0.9 6e-23 80.2 0.1 2.1 2 0 0 2 2 2 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 ORY49098.1 - 5.6e-13 48.9 1.9 1.4e-12 47.6 1.9 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 ORY49098.1 - 1.2e-11 44.8 0.0 3.2e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal MAPEG PF01124.18 ORY49099.1 - 1.6e-13 50.7 1.8 3.1e-13 49.8 1.5 1.6 1 1 0 1 1 1 1 MAPEG family NCE101 PF11654.8 ORY49101.1 - 0.01 15.5 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 Non-classical export protein 1 zf-RING_2 PF13639.6 ORY49103.1 - 7e-10 39.1 4.2 7e-10 39.1 4.2 3.6 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY49103.1 - 2.6e-09 36.8 4.2 2.6e-09 36.8 4.2 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY49103.1 - 1.8e-08 34.3 6.7 1.8e-08 34.3 6.7 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY49103.1 - 6e-08 32.4 3.5 6e-08 32.4 3.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY49103.1 - 8.8e-07 28.7 0.9 8.8e-07 28.7 0.9 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 ORY49103.1 - 1.6e-06 27.8 2.2 4.5e-06 26.4 2.2 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 ORY49103.1 - 3.3e-06 27.2 5.2 1.2e-05 25.4 5.2 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 ORY49103.1 - 3.5e-06 27.2 2.2 3.5e-06 27.2 2.2 3.2 3 0 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 ORY49103.1 - 8.2e-05 22.5 3.1 8.2e-05 22.5 3.1 2.5 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY49103.1 - 0.00011 21.9 2.9 0.00011 21.9 2.9 2.3 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 ORY49103.1 - 0.059 13.0 7.9 0.069 12.8 1.7 2.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 ORY49103.1 - 0.084 12.7 0.4 0.084 12.7 0.4 3.0 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 ORY49103.1 - 3 7.7 16.1 2.4 8.0 0.8 3.0 3 0 0 3 3 3 0 RING-like zinc finger Transcrip_reg PF01709.20 ORY49104.1 - 9.1e-56 189.0 0.7 1.1e-55 188.7 0.7 1.0 1 0 0 1 1 1 1 Transcriptional regulator YgaB PF14182.6 ORY49104.1 - 0.88 10.0 3.0 4.7 7.7 0.0 2.8 2 1 1 3 3 3 0 YgaB-like protein Aldedh PF00171.22 ORY49105.1 - 7.1e-167 555.6 0.0 7.9e-167 555.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family zf-CCHC PF00098.23 ORY49106.1 - 0.0001 22.2 0.9 0.0001 22.2 0.9 2.4 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.6 ORY49106.1 - 1.7 8.5 5.8 7.7 6.3 0.3 2.3 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.6 ORY49106.1 - 2.1 8.2 9.0 8.2 6.4 1.9 2.9 2 0 0 2 2 2 0 Zinc knuckle BUD22 PF09073.10 ORY49106.1 - 2.3 7.5 42.6 0.071 12.5 15.6 3.5 4 0 0 4 4 4 0 BUD22 PPL5 PF18168.1 ORY49106.1 - 3.1 7.0 22.1 0.027 13.8 4.3 2.8 2 1 1 3 3 3 0 Prim-pol family 5 zf-C2H2_10 PF16588.5 ORY49106.1 - 5.5 6.8 10.7 0.3 10.9 1.0 2.3 1 1 1 2 2 2 0 C2H2 zinc-finger Guanylate_cyc PF00211.20 ORY49107.1 - 0.00038 20.1 0.0 0.00069 19.3 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain peroxidase PF00141.23 ORY49109.1 - 7.7e-27 94.5 0.0 1.6e-26 93.4 0.0 1.5 1 0 0 1 1 1 1 Peroxidase Peroxidase_ext PF11895.8 ORY49109.1 - 3.5 7.6 8.0 0.68 9.9 0.1 2.9 3 0 0 3 3 3 0 Fungal peroxidase extension region Mucin PF01456.17 ORY49110.1 - 0.084 12.9 20.6 0.14 12.2 20.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Orthopox_A5L PF06193.11 ORY49110.1 - 0.34 10.3 8.3 0.44 10.0 8.3 1.1 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like RNase_P_Rpp14 PF01900.19 ORY49111.1 - 0.00036 20.7 0.0 0.0006 20.0 0.0 1.3 1 0 0 1 1 1 1 Rpp14/Pop5 family Atg14 PF10186.9 ORY49112.1 - 1.5e-13 50.6 0.0 1.7e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Atg14 PF10186.9 ORY49113.1 - 0.0002 20.6 1.4 0.00034 19.8 1.4 1.3 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Glyco_transf_8 PF01501.20 ORY49114.1 - 0.0072 15.9 0.2 0.014 15.0 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_8 PF01501.20 ORY49115.1 - 0.01 15.4 0.1 0.019 14.5 0.1 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 8 Clr2_transil PF16761.5 ORY49116.1 - 3.8e-17 62.9 0.6 8.8e-17 61.7 0.6 1.6 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 AAR2 PF05282.11 ORY49116.1 - 0.2 11.0 8.3 0.49 9.7 8.3 1.6 1 0 0 1 1 1 0 AAR2 protein TIR_2 PF13676.6 ORY49118.1 - 1.6e-09 38.4 0.0 2e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 TIR domain TIR PF01582.20 ORY49118.1 - 0.032 14.0 0.0 0.038 13.8 0.0 1.2 1 0 0 1 1 1 0 TIR domain Ank_4 PF13637.6 ORY49119.1 - 2.3e-20 72.7 0.0 4.6e-12 46.2 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY49119.1 - 5.3e-20 71.2 1.7 3.3e-12 46.4 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY49119.1 - 3.3e-15 55.7 0.9 2.7e-07 30.7 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 ORY49119.1 - 7.8e-15 53.5 0.1 6.3e-07 29.2 0.0 2.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 ORY49119.1 - 1.6e-14 54.3 0.0 2.1e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Stress-antifung PF01657.17 ORY49121.1 - 0.2 12.3 1.6 0.34 11.6 1.6 1.5 1 1 0 1 1 1 0 Salt stress response/antifungal PAM2 PF07145.15 ORY49122.1 - 0.02 14.5 0.1 0.083 12.6 0.1 2.1 1 0 0 1 1 1 0 Ataxin-2 C-terminal region Flavokinase PF01687.17 ORY49123.1 - 4.3e-33 113.9 0.0 5.1e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase p450 PF00067.22 ORY49124.1 - 6.9e-69 232.8 0.0 8e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 HMG_CoA_synt_C PF08540.10 ORY49125.1 - 3.2e-96 322.3 0.6 3.9e-96 321.9 0.6 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 ORY49125.1 - 3e-78 261.7 0.4 6e-78 260.7 0.4 1.5 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III_C PF08541.10 ORY49125.1 - 0.09 13.0 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal EF-hand_1 PF00036.32 ORY49126.1 - 1e-33 112.3 15.5 8e-09 34.4 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORY49126.1 - 2.3e-30 104.9 4.6 1.5e-14 54.2 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY49126.1 - 3.6e-27 91.9 12.9 1.8e-08 33.6 0.1 4.8 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 ORY49126.1 - 4.2e-26 90.6 11.8 3e-13 49.4 0.3 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 ORY49126.1 - 1.5e-22 78.0 14.1 3.2e-06 26.4 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 ORY49126.1 - 5.7e-13 49.0 0.1 3.8e-08 33.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 ORY49126.1 - 3e-07 30.7 0.2 0.0013 19.0 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 ORY49126.1 - 1.8e-05 24.6 0.0 0.13 12.3 0.0 2.6 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_4 PF12763.7 ORY49126.1 - 4.6e-05 23.3 0.8 0.062 13.3 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 ORY49126.1 - 8.6e-05 22.5 0.4 0.0066 16.4 0.1 2.2 1 1 1 2 2 2 1 Tellurite resistance protein TerB EFhand_Ca_insen PF08726.10 ORY49126.1 - 0.00012 22.1 0.5 0.00025 21.1 0.1 1.8 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 ORY49126.1 - 0.00013 22.1 1.7 0.74 10.1 0.2 3.0 1 1 2 3 3 3 3 Dockerin type I domain EF-hand_11 PF08976.11 ORY49126.1 - 0.00064 20.6 0.0 0.022 15.6 0.0 2.0 1 1 1 2 2 2 1 EF-hand domain RNA_pol_Rpb4 PF03874.16 ORY49126.1 - 0.0042 17.4 0.6 1.2 9.5 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb4 Caleosin PF05042.13 ORY49126.1 - 0.0062 16.5 0.9 3.5 7.5 0.0 3.2 1 1 2 3 3 3 1 Caleosin related protein DUF5580 PF17743.1 ORY49126.1 - 0.0062 15.1 0.0 0.0069 15.0 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 ORY49126.1 - 0.0084 16.4 0.1 0.13 12.6 0.0 2.3 1 1 1 2 2 2 1 EF-hand domain DUF4497 PF14924.6 ORY49126.1 - 0.016 15.6 0.0 1.9 9.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) DUF3349 PF11829.8 ORY49126.1 - 0.019 15.7 0.2 8.6 7.2 0.0 2.7 1 1 3 4 4 4 0 Protein of unknown function (DUF3349) MotA_activ PF09114.10 ORY49126.1 - 0.044 13.9 0.0 0.43 10.7 0.0 2.1 2 0 0 2 2 2 0 Transcription factor MotA, activation domain AAA_assoc_C PF09821.9 ORY49126.1 - 0.069 13.7 1.7 0.16 12.5 0.2 2.3 2 1 0 3 3 2 0 C-terminal AAA-associated domain Spore_III_AB PF09548.10 ORY49126.1 - 0.13 12.4 0.6 0.18 11.9 0.6 1.4 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Mst1_SARAH PF11629.8 ORY49126.1 - 0.25 11.4 3.0 0.72 10.0 0.1 2.7 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 EF-hand_7 PF13499.6 ORY49127.1 - 4e-30 104.1 3.3 3e-16 59.6 2.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORY49127.1 - 1.4e-28 96.3 4.2 5.7e-08 31.8 0.8 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 ORY49127.1 - 3.9e-22 76.2 3.1 1.8e-07 30.6 0.6 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 ORY49127.1 - 1.2e-19 69.9 9.7 2.2e-09 37.0 1.8 4.0 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 ORY49127.1 - 7.4e-17 60.0 7.5 3.3e-06 26.4 0.9 4.4 4 0 0 4 4 4 4 EF hand EF-hand_4 PF12763.7 ORY49127.1 - 1.1e-07 31.8 1.8 1.9e-05 24.5 0.3 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORY49127.1 - 1.8e-06 28.2 0.9 0.0031 17.8 0.4 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 ORY49127.1 - 9.3e-06 25.9 0.0 0.14 12.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EFhand_Ca_insen PF08726.10 ORY49127.1 - 0.00073 19.6 0.9 0.0023 18.0 0.2 2.2 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Dockerin_1 PF00404.18 ORY49127.1 - 0.0011 19.2 3.2 3.8 7.8 1.6 3.2 2 1 0 2 2 2 2 Dockerin type I domain SurA_N_3 PF13624.6 ORY49127.1 - 0.0018 18.1 0.5 0.13 12.1 0.1 2.1 1 1 1 2 2 2 1 SurA N-terminal domain Caleosin PF05042.13 ORY49127.1 - 0.0023 17.9 1.0 0.38 10.7 0.0 2.8 2 1 1 3 3 3 1 Caleosin related protein SurA_N_2 PF13623.6 ORY49127.1 - 0.042 13.7 0.2 0.97 9.3 0.0 2.3 1 1 1 2 2 2 0 SurA N-terminal domain DUF3349 PF11829.8 ORY49127.1 - 0.049 14.4 0.4 22 5.9 0.1 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF3349) DUF1296 PF06972.11 ORY49127.1 - 0.054 13.6 0.0 0.64 10.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1296) EF-hand_11 PF08976.11 ORY49127.1 - 0.061 14.2 0.1 0.45 11.4 0.0 1.9 1 1 1 2 2 2 0 EF-hand domain SPOUT_MTase PF02590.17 ORY49127.1 - 0.069 13.1 0.1 5.1 7.1 0.0 2.1 1 1 1 2 2 2 0 Predicted SPOUT methyltransferase GST_N_2 PF13409.6 ORY49128.1 - 7.6e-12 45.4 0.0 2.8e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY49128.1 - 1.5e-10 41.3 0.0 3.4e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Hemerythrin PF01814.23 ORY49128.1 - 7.1e-07 29.9 0.4 1.4e-06 29.0 0.4 1.5 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain GST_C_3 PF14497.6 ORY49128.1 - 4.5e-06 26.8 0.0 1.1e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY49128.1 - 6.3e-06 26.1 0.0 1.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY49128.1 - 5.9e-05 23.3 0.0 0.00019 21.7 0.0 1.9 2 0 0 2 2 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 ORY49128.1 - 0.00039 20.9 0.0 0.0011 19.5 0.0 1.8 2 0 0 2 2 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 ORY49128.1 - 0.00075 20.2 0.0 0.0022 18.7 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C PF00043.25 ORY49128.1 - 0.015 15.5 0.0 0.038 14.2 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 ORY49128.1 - 0.027 14.8 0.0 0.071 13.4 0.0 1.7 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Glutaredoxin2_C PF04399.13 ORY49128.1 - 0.049 13.5 0.1 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain PH_12 PF16457.5 ORY49129.1 - 6.9e-32 110.8 0.0 1.7e-31 109.6 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain ELMO_CED12 PF04727.13 ORY49129.1 - 3.3e-25 89.2 0.0 6.5e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.8 ORY49129.1 - 2.6e-15 56.7 2.3 5.1e-15 55.7 2.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) DUF5065 PF16723.5 ORY49129.1 - 0.15 12.2 0.0 0.48 10.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5065) ABC2_membrane PF01061.24 ORY49130.1 - 9.7e-50 168.9 47.8 6.7e-28 97.6 15.3 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 ORY49130.1 - 4.8e-48 163.1 0.0 2.3e-25 89.7 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ORY49130.1 - 2.3e-12 47.3 7.5 6.3e-05 22.9 0.0 4.2 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORY49130.1 - 6.8e-07 29.3 0.7 0.00089 19.2 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 ORY49130.1 - 0.00017 22.1 1.9 0.0045 17.5 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY49130.1 - 0.00037 20.9 0.2 0.14 12.5 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 ORY49130.1 - 0.00061 20.3 0.0 0.89 10.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ORY49130.1 - 0.00087 19.0 2.9 0.089 12.5 0.3 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.6 ORY49130.1 - 0.0017 18.5 0.1 1.6 8.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 ORY49130.1 - 0.0033 17.6 0.5 2.7 8.3 0.1 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 ORY49130.1 - 0.0043 17.3 0.5 0.63 10.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 ORY49130.1 - 0.032 14.1 0.9 7.3 6.5 0.1 2.6 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 ORY49130.1 - 0.035 14.2 3.2 2.7 8.1 0.2 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.6 ORY49130.1 - 0.053 13.2 0.4 10 5.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 ORY49130.1 - 0.065 12.8 2.5 1.3 8.5 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 ORY49130.1 - 0.11 12.8 3.8 0.67 10.2 0.2 2.9 3 1 0 3 3 2 0 AAA domain Dynamin_N PF00350.23 ORY49130.1 - 0.13 12.3 0.8 14 5.7 0.1 2.5 2 0 0 2 2 2 0 Dynamin family PduV-EutP PF10662.9 ORY49130.1 - 0.13 12.0 0.2 19 5.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 ORY49130.1 - 0.15 11.8 0.2 6.9 6.3 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ORY49130.1 - 0.26 10.8 0.7 11 5.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 ORY49130.1 - 0.46 9.8 2.9 3.6 6.9 0.3 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.14 ORY49130.1 - 0.51 10.2 1.3 15 5.5 0.2 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B APH PF01636.23 ORY49132.1 - 3.2e-06 27.2 0.1 4.7e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 ORY49132.1 - 0.0024 17.3 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 ORY49132.1 - 0.015 14.9 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF2053 PF09767.9 ORY49132.1 - 0.023 14.8 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2053) DUF1679 PF07914.11 ORY49132.1 - 0.061 12.2 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) DUF2476 PF10630.9 ORY49133.1 - 0.24 11.5 3.8 0.43 10.7 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2476) Hemerythrin PF01814.23 ORY49134.1 - 8.6e-05 23.2 0.0 0.00014 22.5 0.0 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain RalF_SCD PF18248.1 ORY49134.1 - 0.12 12.3 0.0 0.51 10.3 0.0 2.0 2 0 0 2 2 2 0 RalF C-terminal Sec-7 capping domain DUF4604 PF15377.6 ORY49135.1 - 0.59 10.5 24.8 0.72 10.3 24.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) LAP1C PF05609.12 ORY49135.1 - 0.78 8.8 10.8 0.91 8.5 10.8 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) FancD2 PF14631.6 ORY49135.1 - 1.6 6.0 12.4 2 5.7 12.4 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RR_TM4-6 PF06459.12 ORY49135.1 - 2.1 8.1 15.6 2.5 7.9 15.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MDFI PF15316.6 ORY49135.1 - 4.3 7.4 10.8 4.8 7.2 10.8 1.1 1 0 0 1 1 1 0 MyoD family inhibitor DUF913 PF06025.12 ORY49135.1 - 8.1 5.3 8.3 9.3 5.1 8.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SLC12 PF03522.15 ORY49135.1 - 8.2 5.3 13.5 9.4 5.1 13.5 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF4614 PF15391.6 ORY49136.1 - 0.00012 22.2 1.2 0.00012 22.2 1.2 5.2 5 1 0 5 5 5 1 Domain of unknown function (DUF4614) DUF5082 PF16888.5 ORY49136.1 - 0.059 13.6 0.2 0.059 13.6 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) Fib_alpha PF08702.10 ORY49136.1 - 9.1 6.5 9.0 6.4 7.0 0.1 3.7 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family adh_short PF00106.25 ORY49137.1 - 1.8e-11 43.9 0.0 3.7e-09 36.3 0.0 2.6 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY49137.1 - 5.9e-09 35.8 0.0 0.0027 17.3 0.0 2.7 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY49137.1 - 0.035 14.0 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 KR domain Pectate_lyase22 PF14583.6 ORY49137.1 - 0.08 11.6 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Oligogalacturonate lyase GAF_2 PF13185.6 ORY49139.1 - 4.3e-07 30.3 0.0 5.4e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 ORY49139.1 - 8.5e-05 23.2 0.0 9.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 ORY49139.1 - 0.062 13.6 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 GAF domain MutS_V PF00488.21 ORY49140.1 - 1.8e-74 249.9 0.1 3.3e-74 249.0 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORY49140.1 - 1.4e-32 113.4 0.0 2.7e-32 112.6 0.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 ORY49140.1 - 1.1e-19 70.7 0.5 9.9e-18 64.4 0.5 2.6 1 1 0 1 1 1 1 MutS domain I MutS_II PF05188.17 ORY49140.1 - 5.6e-14 52.6 0.0 2e-13 50.8 0.0 2.0 1 1 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 ORY49140.1 - 7.4e-06 26.2 1.0 3e-05 24.3 1.0 2.1 1 1 0 1 1 1 1 MutS family domain IV RRN3 PF05327.11 ORY49140.1 - 1.6 7.2 5.5 2.5 6.6 5.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Ank_2 PF12796.7 ORY49141.1 - 7.1e-42 141.9 0.0 1.5e-08 35.1 0.0 4.2 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY49141.1 - 2.1e-20 72.8 0.6 0.00012 22.6 0.0 5.6 3 3 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY49141.1 - 1.6e-19 69.7 2.7 0.0083 16.4 0.0 7.0 2 2 5 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY49141.1 - 3.1e-14 51.7 0.4 0.78 10.5 0.0 8.6 9 0 0 9 9 9 3 Ankyrin repeat Ank PF00023.30 ORY49141.1 - 2.3e-10 40.4 0.0 14 6.4 0.0 8.3 5 3 3 8 8 8 2 Ankyrin repeat BTB PF00651.31 ORY49142.1 - 2.1e-12 47.3 0.0 4.2e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain TLD PF07534.16 ORY49142.1 - 1.9e-08 34.6 0.7 3.2e-08 33.9 0.7 1.3 1 0 0 1 1 1 1 TLD Proteasome PF00227.26 ORY49143.1 - 1.3e-44 152.0 0.1 1.6e-44 151.7 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Tim17 PF02466.19 ORY49144.1 - 4.4e-17 62.5 7.7 6.4e-17 61.9 7.7 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pantoate_ligase PF02569.15 ORY49145.1 - 7e-98 327.1 0.0 9.3e-98 326.7 0.0 1.1 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase DUF3097 PF11296.8 ORY49145.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3097) AAA PF00004.29 ORY49146.1 - 3.6e-43 147.2 0.0 6.6e-43 146.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY49146.1 - 1.1e-07 31.6 0.2 1.9e-07 30.8 0.2 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 ORY49146.1 - 1.1e-07 31.7 0.1 2.6e-07 30.5 0.1 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 ORY49146.1 - 6.4e-07 29.6 0.0 1.4e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 ORY49146.1 - 4.8e-06 26.9 0.1 0.003 17.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 ORY49146.1 - 3.5e-05 23.8 0.2 0.00037 20.5 0.2 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 ORY49146.1 - 9.5e-05 21.7 0.0 0.00017 20.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 ORY49146.1 - 0.00018 21.3 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY49146.1 - 0.00034 21.1 0.1 0.0096 16.3 0.1 2.4 1 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 ORY49146.1 - 0.001 18.8 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 ORY49146.1 - 0.0015 19.0 0.0 0.0046 17.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_28 PF13521.6 ORY49146.1 - 0.0026 18.0 0.2 0.012 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORY49146.1 - 0.0031 17.7 0.0 0.0061 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 ORY49146.1 - 0.0091 16.0 0.1 0.025 14.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ORY49146.1 - 0.01 16.2 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 ORY49146.1 - 0.014 14.6 0.0 0.025 13.8 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 ORY49146.1 - 0.018 14.5 0.1 0.034 13.5 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 ORY49146.1 - 0.021 14.7 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 ORY49146.1 - 0.024 14.2 1.5 0.75 9.3 0.2 2.6 2 1 0 3 3 2 0 AAA domain ATPase PF06745.13 ORY49146.1 - 0.025 13.9 0.1 0.65 9.3 0.0 2.7 4 0 0 4 4 4 0 KaiC PhoH PF02562.16 ORY49146.1 - 0.025 14.0 0.0 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_7 PF12775.7 ORY49146.1 - 0.058 12.9 0.1 0.14 11.6 0.1 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 ORY49146.1 - 0.062 13.0 0.2 0.18 11.5 0.2 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ORY49146.1 - 0.097 13.2 0.1 0.35 11.4 0.0 1.9 1 1 0 1 1 1 0 ABC transporter TsaE PF02367.17 ORY49146.1 - 0.16 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 ORY49146.1 - 0.19 11.5 0.6 0.45 10.2 0.2 2.0 2 1 0 2 2 2 0 AAA domain RNase_PH_C PF03725.15 ORY49147.1 - 4e-10 39.6 0.0 1.1e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 RNase_PH PF01138.21 ORY49147.1 - 1.3e-07 32.1 0.2 3.4e-07 30.8 0.2 1.7 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 AAA_16 PF13191.6 ORY49148.1 - 7.6e-06 26.4 0.0 1.6e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Sterile PF03015.19 ORY49150.1 - 0.00048 20.3 0.2 0.7 10.2 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein ERO1 PF04137.15 ORY49151.1 - 6.1e-100 334.8 0.0 7.9e-100 334.5 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Pex2_Pex12 PF04757.14 ORY49152.1 - 3.9e-11 43.0 0.2 2.5e-10 40.3 0.2 1.9 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-CCHC PF00098.23 ORY49153.1 - 3e-23 80.8 44.7 2.5e-05 24.2 0.7 6.4 6 0 0 6 6 6 6 Zinc knuckle zf-CCHC_4 PF14392.6 ORY49153.1 - 3.8e-07 29.7 38.6 0.0072 16.0 1.3 6.0 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_2 PF13696.6 ORY49153.1 - 0.013 15.3 1.0 0.013 15.3 1.0 5.8 6 0 0 6 6 6 0 Zinc knuckle zf-CCHC_5 PF14787.6 ORY49153.1 - 0.12 12.1 37.2 0.52 10.1 0.5 5.9 4 1 2 6 6 6 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 ORY49153.1 - 0.68 9.9 32.7 2.6 8.1 0.5 5.3 3 2 2 5 5 5 0 Zinc knuckle Glyco_transf_8 PF01501.20 ORY49154.1 - 0.019 14.6 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 8 BTB PF00651.31 ORY49155.1 - 1.2e-14 54.5 0.1 3.7e-14 52.9 0.1 1.9 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 ORY49156.1 - 3.5e-14 53.0 0.0 6.5e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain TLD PF07534.16 ORY49156.1 - 0.0046 17.2 0.1 0.0094 16.2 0.1 1.6 1 0 0 1 1 1 1 TLD BTB PF00651.31 ORY49157.1 - 1.4e-06 28.5 0.0 1.1e-05 25.6 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain 2-Hacid_dh_C PF02826.19 ORY49158.1 - 2.9e-39 134.2 0.1 6.5e-39 133.1 0.1 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY49158.1 - 2.8e-07 30.2 0.1 0.00055 19.6 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ORY49158.1 - 0.0092 16.2 0.9 0.014 15.6 0.2 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Ribonuc_2-5A PF06479.12 ORY49159.1 - 1.7e-43 147.8 0.2 4.1e-43 146.6 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase PF00069.25 ORY49159.1 - 2.1e-33 115.9 0.0 1e-32 113.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY49159.1 - 2.9e-20 72.6 0.0 4e-19 68.9 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY49159.1 - 9e-06 24.7 0.1 1.7e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORY49159.1 - 0.013 14.9 0.4 0.032 13.6 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 ORY49159.1 - 0.095 12.0 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Kinase-like HMG_box PF00505.19 ORY49161.1 - 0.011 16.1 5.3 0.011 16.1 5.3 2.8 3 0 0 3 3 3 0 HMG (high mobility group) box DUF2828 PF11443.8 ORY49161.1 - 0.24 9.4 2.5 0.26 9.3 2.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Muted PF14942.6 ORY49161.1 - 0.56 10.5 4.2 0.16 12.3 1.3 1.6 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein HMG_box_2 PF09011.10 ORY49161.1 - 3.9 8.1 10.0 0.42 11.2 5.1 2.0 2 1 0 2 2 2 0 HMG-box domain Thioredoxin PF00085.20 ORY49162.1 - 5.6e-26 90.5 0.0 6.4e-26 90.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY49162.1 - 0.0001 22.7 0.3 0.0022 18.4 0.3 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 ORY49162.1 - 0.00018 20.9 0.0 0.00021 20.7 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 ORY49162.1 - 0.0012 18.7 0.0 0.0014 18.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 ORY49162.1 - 0.0021 18.4 0.0 0.0036 17.6 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 ORY49162.1 - 0.068 13.1 0.1 0.26 11.2 0.1 1.6 1 1 1 2 2 2 0 AhpC/TSA family Thioredoxin_7 PF13899.6 ORY49162.1 - 0.14 12.3 0.2 0.26 11.5 0.2 1.6 1 1 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.24 ORY49162.1 - 0.16 12.2 0.2 0.35 11.1 0.2 1.6 1 1 0 1 1 1 0 Glutaredoxin Sulfate_transp PF00916.20 ORY49163.1 - 6.2e-98 328.0 25.5 8.1e-98 327.6 25.5 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 ORY49163.1 - 7.9e-13 48.1 0.0 1.6e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 ORY49163.1 - 0.023 15.1 15.5 0.029 14.8 4.6 3.0 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily STAS_2 PF13466.6 ORY49163.1 - 0.024 15.0 0.0 0.052 13.9 0.0 1.5 1 0 0 1 1 1 0 STAS domain OPT PF03169.15 ORY49164.1 - 2.5e-111 373.3 52.8 4.3e-110 369.2 52.8 2.0 1 1 0 1 1 1 1 OPT oligopeptide transporter protein DUF2109 PF09882.9 ORY49164.1 - 1.2 9.2 5.7 0.94 9.5 0.7 3.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) Thioredoxin PF00085.20 ORY49165.1 - 5.6e-26 90.5 0.1 6.7e-26 90.3 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 ORY49165.1 - 8.8e-06 26.0 0.0 1.1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 ORY49165.1 - 0.00028 20.8 0.0 0.00035 20.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 ORY49165.1 - 0.059 13.1 0.1 0.081 12.6 0.1 1.2 1 0 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.6 ORY49165.1 - 0.099 12.4 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.6 ORY49165.1 - 0.099 13.1 0.2 0.23 11.9 0.2 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain UBX PF00789.20 ORY49166.1 - 3.2e-19 68.9 0.0 6.9e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 ORY49166.1 - 1.4e-06 28.0 0.5 3.1e-06 27.0 0.5 1.6 1 0 0 1 1 1 1 UBA/TS-N domain DUF572 PF04502.13 ORY49166.1 - 0.00028 20.6 10.3 0.00036 20.3 10.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF724 PF05266.14 ORY49166.1 - 3.2 7.5 23.3 6.2 6.6 22.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Glyco_hydro_18 PF00704.28 ORY49167.1 - 4.3e-13 49.7 0.4 5.6e-13 49.3 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ETRAMP PF09716.10 ORY49167.1 - 0.011 15.7 1.1 0.023 14.8 1.1 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF515 PF04415.12 ORY49167.1 - 0.046 12.1 0.1 0.067 11.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Methyltransf_21 PF05050.12 ORY49170.1 - 2e-14 54.0 0.0 3.6e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain BMF PF15185.6 ORY49170.1 - 0.00022 21.0 0.0 0.00036 20.3 0.0 1.4 1 0 0 1 1 1 1 Bcl-2-modifying factor, apoptosis V_cholerae_RfbT PF05575.11 ORY49170.1 - 0.038 13.3 0.0 6.5 5.9 0.0 2.1 2 0 0 2 2 2 0 Vibrio cholerae RfbT protein Methyltransf_23 PF13489.6 ORY49170.1 - 0.079 12.8 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Tau95 PF09734.9 ORY49171.1 - 1.4e-26 93.9 3.7 1.5e-26 93.9 1.1 2.2 3 0 0 3 3 3 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 ORY49171.1 - 7.1e-24 84.4 0.1 2.1e-23 82.9 0.0 1.9 2 0 0 2 2 2 1 Tau95 Triple barrel domain DNA_primase_lrg PF04104.14 ORY49171.1 - 0.14 11.5 0.2 0.23 10.9 0.2 1.3 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit Lipoprotein_2 PF00921.17 ORY49171.1 - 0.15 11.6 2.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Borrelia lipoprotein Pkinase PF00069.25 ORY49172.1 - 1.4e-72 244.2 0.0 1.7e-72 244.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY49172.1 - 9.5e-36 123.4 0.0 1.2e-35 123.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY49172.1 - 2.4e-06 27.1 0.0 2.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 ORY49172.1 - 0.0071 16.0 0.3 0.16 11.5 0.1 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 ORY49172.1 - 0.095 11.6 0.5 0.13 11.1 0.5 1.1 1 0 0 1 1 1 0 Haspin like kinase domain C2 PF00168.30 ORY49173.1 - 2.7e-20 72.6 0.0 6.5e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.17 ORY49173.1 - 1.5e-05 25.6 0.0 5.6 7.7 0.0 4.0 3 0 0 3 3 3 3 Putative heavy-metal-binding Ribosomal_L38e PF01781.18 ORY49175.1 - 3.6e-34 116.7 3.1 3.9e-34 116.6 3.1 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family DUF5305 PF17231.2 ORY49177.1 - 0.24 10.8 0.0 1.2 8.5 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5305) DUF1427 PF07235.11 ORY49179.1 - 4.3 7.3 5.2 99 3.0 5.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1427) DUF2809 PF10990.8 ORY49181.1 - 0.016 15.9 1.2 0.025 15.2 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2809) LapA_dom PF06305.11 ORY49181.1 - 0.034 14.0 0.8 4 7.3 0.1 2.3 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain TctA PF01970.16 ORY49181.1 - 0.17 10.6 2.7 0.22 10.2 2.7 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family zf-C2H2_jaz PF12171.8 ORY49182.1 - 0.023 15.0 0.2 0.056 13.7 0.2 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DUF16 PF01519.16 ORY49184.1 - 0.0047 17.4 0.0 0.0071 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF16 Baculo_PEP_C PF04513.12 ORY49184.1 - 0.48 10.5 3.6 0.33 11.0 0.3 2.0 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2976 PF11190.8 ORY49187.1 - 0.045 13.6 5.2 0.22 11.3 0.6 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2976) Musclin PF11037.8 ORY49187.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle DUF4282 PF14110.6 ORY49187.1 - 0.67 10.7 0.0 0.67 10.7 0.0 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4282) Claudin_3 PF06653.11 ORY49187.1 - 4.9 7.1 25.1 0.49 10.3 6.4 2.9 1 1 2 3 3 3 0 Tight junction protein, Claudin-like ATG101 PF07855.12 ORY49188.1 - 8.9e-26 90.7 0.1 1.2e-25 90.3 0.1 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 Acyltransferase PF01553.21 ORY49189.1 - 2.3e-07 30.5 0.0 3.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Phage_holin_3_6 PF07332.11 ORY49189.1 - 0.0064 16.5 1.1 0.01 15.9 1.1 1.3 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III TMEM37 PF15108.6 ORY49189.1 - 0.16 11.8 0.6 0.32 10.9 0.6 1.4 1 0 0 1 1 1 0 Voltage-dependent calcium channel gamma-like subunit protein family TFIIIC_sub6 PF10419.9 ORY49190.1 - 6.2e-13 48.4 0.0 8.5e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain tRNA-synt_1b PF00579.25 ORY49192.1 - 1.2e-17 64.2 0.0 3.5e-12 46.2 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) PLAC8 PF04749.17 ORY49193.1 - 1.7e-05 25.8 9.5 2.2e-05 25.4 9.5 1.2 1 0 0 1 1 1 1 PLAC8 family Cyt-b5 PF00173.28 ORY49194.1 - 5.4e-15 55.3 0.0 6.8e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MFS_1 PF07690.16 ORY49195.1 - 2.1e-14 53.2 45.3 6.3e-12 45.1 32.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF5423 PF17461.2 ORY49195.1 - 0.055 12.3 0.1 0.093 11.6 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) MFS_1 PF07690.16 ORY49196.1 - 1.1e-16 60.7 29.4 1.1e-16 60.7 29.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF5423 PF17461.2 ORY49196.1 - 0.045 12.6 0.0 0.076 11.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Sel1 PF08238.12 ORY49199.1 - 0.00067 20.3 0.5 0.17 12.6 0.0 3.3 3 0 0 3 3 3 1 Sel1 repeat RsgA_GTPase PF03193.16 ORY49303.1 - 0.00028 20.9 0.6 4.9 7.0 0.0 3.1 1 1 1 3 3 3 2 RsgA GTPase MLD PF11647.8 ORY49303.1 - 0.0014 18.9 0.1 7.1 7.0 0.0 3.2 3 0 0 3 3 3 1 Membrane Localization Domain K1 PF02960.14 ORY49303.1 - 0.0016 18.5 1.0 0.7 10.0 0.0 2.9 1 1 2 3 3 3 1 K1 glycoprotein DUF4427 PF14468.6 ORY49303.1 - 0.019 15.0 1.0 1.3 9.1 0.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF4427) DUF3754 PF12576.8 ORY49303.1 - 0.077 12.9 1.0 2.2 8.2 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3754) PBS_linker_poly PF00427.21 ORY49303.1 - 0.085 12.9 0.2 6 6.9 0.0 2.3 1 1 1 2 2 2 0 Phycobilisome Linker polypeptide CPSase_sm_chain PF00988.22 ORY49303.1 - 0.11 12.3 0.9 21 5.0 0.0 3.2 1 1 2 3 3 3 0 Carbamoyl-phosphate synthase small chain, CPSase domain Malic_M PF03949.15 ORY49303.1 - 0.15 11.3 0.9 15 4.7 0.1 2.7 1 1 2 3 3 3 0 Malic enzyme, NAD binding domain PTR PF12789.7 ORY49303.1 - 0.38 10.8 2.0 14 5.8 0.1 2.6 3 0 0 3 3 3 0 Phage tail repeat like RsgA_GTPase PF03193.16 ORY49304.1 - 0.00014 21.8 0.4 4.3 7.2 0.0 3.0 1 1 2 3 3 3 2 RsgA GTPase DUF4427 PF14468.6 ORY49304.1 - 0.0027 17.8 1.1 1.4 9.0 0.1 2.4 1 1 2 3 3 3 2 Protein of unknown function (DUF4427) PBS_linker_poly PF00427.21 ORY49304.1 - 0.018 15.1 0.1 3.2 7.8 0.0 2.4 1 1 1 2 2 2 0 Phycobilisome Linker polypeptide Reprolysin PF01421.19 ORY49304.1 - 0.033 14.1 1.3 32 4.3 0.0 3.1 1 1 2 3 3 3 0 Reprolysin (M12B) family zinc metalloprotease CAS_C PF12026.8 ORY49304.1 - 0.058 13.5 0.3 12 5.9 0.1 2.1 2 0 0 2 2 2 0 Crk-Associated Substrate C-terminal domain HECA PF15353.6 ORY49304.1 - 0.073 13.3 0.0 9.8 6.5 0.0 2.3 1 1 1 2 2 2 0 Headcase protein family homologue Malic_M PF03949.15 ORY49304.1 - 0.18 11.0 1.0 17 4.6 0.0 2.7 1 1 2 3 3 3 0 Malic enzyme, NAD binding domain RINGv PF12906.7 ORY49304.1 - 0.24 11.5 2.6 44 4.3 0.0 3.0 3 0 0 3 3 3 0 RING-variant domain DUF478 PF04334.12 ORY49304.1 - 0.28 11.3 5.1 8.7 6.5 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF478) Baculo_PEP_C PF04513.12 ORY49305.1 - 0.0016 18.5 4.0 0.0016 18.5 4.0 2.5 3 0 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus HSBP1 PF06825.12 ORY49305.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 DUF2374 PF09574.10 ORY49306.1 - 0.015 15.1 0.1 0.063 13.1 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (Duf2374) CLP1_P PF16575.5 ORY49308.1 - 1.8e-38 132.3 0.0 7.9e-38 130.1 0.0 2.0 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 ORY49308.1 - 0.046 13.5 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY49308.1 - 0.071 13.5 0.0 0.52 10.7 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 ORY49308.1 - 0.075 13.3 0.0 0.24 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 ORY49308.1 - 0.18 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 ORY49308.1 - 0.2 11.5 0.0 0.38 10.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Abhydrolase_2 PF02230.16 ORY49309.1 - 1.5e-08 34.7 0.0 1.7e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase LIP PF03583.14 ORY49309.1 - 0.0065 15.8 0.0 1.9 7.7 0.0 2.1 2 0 0 2 2 2 2 Secretory lipase DLH PF01738.18 ORY49309.1 - 0.013 15.1 0.0 0.014 15.0 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family Palm_thioest PF02089.15 ORY49309.1 - 0.014 15.3 0.0 0.016 15.1 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_5 PF12695.7 ORY49309.1 - 0.031 14.0 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 ORY49309.1 - 0.034 13.8 0.0 0.17 11.5 0.0 1.9 1 1 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.8 ORY49309.1 - 0.055 12.7 0.2 1.1 8.5 0.1 2.0 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY49309.1 - 0.062 12.9 0.3 4.8 6.7 0.1 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY49309.1 - 0.099 13.2 0.0 0.17 12.4 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 ORY49309.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein FSH1 PF03959.13 ORY49309.1 - 0.13 11.9 0.2 0.43 10.2 0.2 1.8 1 1 0 1 1 1 0 Serine hydrolase (FSH1) OpuAC PF04069.12 ORY49310.1 - 5e-05 23.0 0.0 9.8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system Ephrin_rec_like PF07699.13 ORY49310.1 - 7.9e-05 22.3 4.6 7.9e-05 22.3 4.6 3.1 4 0 0 4 4 4 1 Putative ephrin-receptor like NCD3G PF07562.14 ORY49310.1 - 0.0011 18.9 2.5 0.0011 18.9 2.5 2.3 2 0 0 2 2 2 1 Nine Cysteines Domain of family 3 GPCR Haspin_kinase PF12330.8 ORY49311.1 - 1.4e-33 116.4 0.0 4.3e-24 85.2 0.0 2.0 2 0 0 2 2 2 2 Haspin like kinase domain LRR_6 PF13516.6 ORY49313.1 - 0.0068 16.4 5.6 1.1 9.4 0.5 3.1 3 0 0 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.7 ORY49313.1 - 0.072 13.5 5.9 0.72 10.4 1.8 2.7 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY49313.1 - 0.13 12.1 0.2 0.95 9.3 0.0 2.6 3 0 0 3 3 3 0 Leucine rich repeat CARD_2 PF16739.5 ORY49313.1 - 0.16 12.0 0.0 0.45 10.5 0.0 1.7 1 0 0 1 1 1 0 Caspase recruitment domain cNMP_binding PF00027.29 ORY49314.1 - 5.2e-15 55.3 0.0 1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HEM4 PF02602.15 ORY49315.1 - 1.9e-34 119.1 0.0 2.4e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TauD PF02668.16 ORY49315.1 - 0.053 13.3 0.0 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family Vps5 PF09325.10 ORY49316.1 - 1.2e-13 51.1 1.2 2.2e-13 50.3 1.2 1.4 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 ORY49316.1 - 6.5e-13 48.7 4.9 8.8e-11 41.8 0.1 3.2 4 0 0 4 4 4 2 PX domain SOG2 PF10428.9 ORY49316.1 - 0.0012 18.1 0.3 0.002 17.4 0.3 1.3 1 0 0 1 1 1 1 RAM signalling pathway protein BAR_3_WASP_bdg PF10456.9 ORY49316.1 - 0.0016 17.9 0.8 0.0037 16.7 0.8 1.6 1 0 0 1 1 1 1 WASP-binding domain of Sorting nexin protein RNase_3_N PF18497.1 ORY49316.1 - 0.22 11.7 2.4 0.42 10.9 1.1 2.0 2 0 0 2 2 2 0 Ribonuclease III N-terminal domain WD40 PF00400.32 ORY49317.1 - 4.1e-09 36.9 14.2 0.5 11.3 0.1 9.0 10 0 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY49317.1 - 5.1e-08 33.1 0.2 2.1 8.7 0.0 6.2 4 3 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY49317.1 - 0.075 12.0 1.5 8.4 5.2 0.0 3.7 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Arm PF00514.23 ORY49318.1 - 9.3e-51 168.4 19.0 3.9e-09 36.2 0.1 10.4 10 1 0 10 10 10 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 ORY49318.1 - 4.6e-17 62.2 2.8 6.5e-05 23.2 1.2 5.0 4 2 1 5 5 5 3 HEAT repeats HEAT_EZ PF13513.6 ORY49318.1 - 1.5e-14 54.1 16.6 1.5e-07 31.8 0.1 8.0 7 2 2 9 9 9 4 HEAT-like repeat HEAT PF02985.22 ORY49318.1 - 1e-13 50.3 15.7 0.0031 17.6 0.1 9.1 10 0 0 10 10 10 3 HEAT repeat Adaptin_N PF01602.20 ORY49318.1 - 3.6e-09 35.7 10.3 3e-07 29.4 10.3 2.9 1 1 0 1 1 1 1 Adaptin N terminal region Arm_2 PF04826.13 ORY49318.1 - 4.6e-07 29.5 9.5 0.0041 16.6 5.6 3.8 2 1 1 3 3 3 2 Armadillo-like Cnd1 PF12717.7 ORY49318.1 - 1.3e-06 28.5 6.8 0.26 11.3 0.2 3.9 2 2 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 KAP PF05804.12 ORY49318.1 - 0.00075 17.8 0.4 0.072 11.2 0.1 2.3 1 1 1 2 2 2 2 Kinesin-associated protein (KAP) DUF3361 PF11841.8 ORY49318.1 - 0.00077 19.4 3.4 0.15 12.0 0.0 3.4 2 2 1 3 3 3 1 Domain of unknown function (DUF3361) HEAT_PBS PF03130.16 ORY49318.1 - 0.0037 17.8 4.0 5.4 8.0 0.2 5.1 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 ORY49318.1 - 0.0093 16.0 3.7 0.56 10.3 0.1 4.0 2 2 2 4 4 4 1 Spinocerebellar ataxia type 10 protein domain V-ATPase_H_N PF03224.14 ORY49318.1 - 0.11 11.8 7.7 3.7 6.8 2.3 3.4 1 1 3 4 4 4 0 V-ATPase subunit H bZIP_1 PF00170.21 ORY49319.1 - 4.1e-05 23.6 12.1 0.00011 22.3 12.1 1.6 1 1 0 1 1 1 1 bZIP transcription factor SlyX PF04102.12 ORY49319.1 - 0.0081 16.8 0.6 0.023 15.3 0.6 1.8 1 0 0 1 1 1 1 SlyX bZIP_2 PF07716.15 ORY49319.1 - 0.0081 16.2 13.9 0.04 14.0 13.9 2.0 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 ORY49319.1 - 0.076 13.5 8.3 0.13 12.8 8.3 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor CALM_bind PF16025.5 ORY49319.1 - 3.8 8.1 11.0 7.1 7.2 5.4 2.4 2 0 0 2 2 2 0 Calcium-dependent calmodulin binding Guanylate_cyc PF00211.20 ORY49320.1 - 2.1e-36 125.3 0.6 5.7e-36 123.9 0.6 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain GAF PF01590.26 ORY49320.1 - 1.3e-32 113.3 0.0 1.8e-17 64.2 0.0 3.4 3 0 0 3 3 3 2 GAF domain GAF_2 PF13185.6 ORY49320.1 - 2.7e-23 82.8 0.0 4.2e-10 40.1 0.0 2.8 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 ORY49320.1 - 2.4e-11 44.1 0.0 4e-07 30.4 0.0 2.9 2 0 0 2 2 2 2 GAF domain TPR_2 PF07719.17 ORY49320.1 - 7.9e-05 22.5 2.2 0.00011 22.1 0.3 2.3 2 0 0 2 2 1 1 Tetratricopeptide repeat DUF3369 PF11849.8 ORY49320.1 - 0.0043 17.3 1.0 0.041 14.1 0.3 2.9 1 1 1 2 2 2 1 Domain of unknown function (DUF3369) TPR_1 PF00515.28 ORY49320.1 - 0.0046 16.7 0.3 0.023 14.5 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY49320.1 - 0.038 14.6 0.0 0.09 13.4 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY49320.1 - 0.1 13.4 0.0 0.4 11.6 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY49320.1 - 0.12 12.7 0.2 1.4 9.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat AcylCoA_dehyd_C PF12186.8 ORY49320.1 - 4.3 7.5 5.4 1.4 9.0 0.9 2.7 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase C terminal Glyco_hydro_26 PF02156.15 ORY49321.1 - 2.6e-07 30.4 5.7 3.7e-07 29.9 5.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 APG6_N PF17675.1 ORY49322.1 - 0.002 18.6 9.1 0.002 18.6 9.1 3.3 1 1 2 3 3 3 1 Apg6 coiled-coil region FPP PF05911.11 ORY49322.1 - 0.0031 15.8 22.3 0.004 15.4 22.3 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil GAS PF13851.6 ORY49322.1 - 0.0031 16.9 11.6 0.0031 16.9 11.6 3.2 1 1 2 3 3 3 2 Growth-arrest specific micro-tubule binding Occludin_ELL PF07303.13 ORY49322.1 - 0.0041 17.8 4.4 0.0041 17.8 4.4 4.0 2 2 3 5 5 5 1 Occludin homology domain FapA PF03961.13 ORY49322.1 - 0.099 11.2 16.0 0.12 11.0 15.0 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A Lip_prot_lig_C PF10437.9 ORY49322.1 - 0.17 11.9 5.0 3.2 7.8 0.2 3.4 1 1 3 4 4 4 0 Bacterial lipoate protein ligase C-terminus FlaC_arch PF05377.11 ORY49322.1 - 0.3 11.5 13.5 3.3 8.2 1.5 4.8 4 1 1 5 5 4 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 ORY49322.1 - 0.32 11.2 27.1 2.5 8.3 11.5 3.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Tropomyosin PF00261.20 ORY49322.1 - 0.53 9.6 21.0 0.91 8.8 9.2 3.1 1 1 1 2 2 2 0 Tropomyosin ATG16 PF08614.11 ORY49322.1 - 0.65 10.2 26.2 2.7 8.2 14.5 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Cep57_MT_bd PF06657.13 ORY49322.1 - 0.75 10.3 20.0 9.4 6.8 0.0 5.4 4 1 2 6 6 5 0 Centrosome microtubule-binding domain of Cep57 BST2 PF16716.5 ORY49322.1 - 0.91 10.2 23.0 1.3 9.7 4.4 4.1 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 Fez1 PF06818.15 ORY49322.1 - 1.2 9.5 22.8 0.54 10.7 16.0 2.3 1 1 1 2 2 2 0 Fez1 Med10 PF09748.9 ORY49322.1 - 1.3 9.0 12.8 0.22 11.5 4.4 2.9 1 1 1 2 2 2 0 Transcription factor subunit Med10 of Mediator complex DUF1664 PF07889.12 ORY49322.1 - 1.5 8.8 18.2 1.4 9.0 6.2 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF745 PF05335.13 ORY49322.1 - 1.8 8.3 16.3 4.4 7.0 0.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Lebercilin PF15619.6 ORY49322.1 - 1.9 8.1 34.9 0.32 10.6 11.9 3.5 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease zf-C4H2 PF10146.9 ORY49322.1 - 2.6 8.3 22.2 0.067 13.5 3.8 2.5 1 1 1 2 2 1 0 Zinc finger-containing protein KASH_CCD PF14662.6 ORY49322.1 - 3.1 7.6 28.1 0.18 11.6 19.0 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Prefoldin_2 PF01920.20 ORY49322.1 - 3.3 7.7 29.6 0.11 12.5 9.9 4.0 2 2 1 4 4 4 0 Prefoldin subunit DUF5082 PF16888.5 ORY49322.1 - 3.8 7.8 22.7 3.1 8.1 9.1 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) NPV_P10 PF05531.12 ORY49322.1 - 4.2 7.9 17.5 6.1 7.4 4.7 3.7 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 ORY49322.1 - 4.2 6.6 15.1 23 4.2 15.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 ORY49322.1 - 4.4 7.3 25.4 15 5.6 20.6 3.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin_1 PF12718.7 ORY49322.1 - 5.6 7.1 28.5 9.2 6.4 20.6 2.9 1 1 2 3 3 3 0 Tropomyosin like DUF2951 PF11166.8 ORY49322.1 - 5.8 7.2 15.4 3.6 7.9 3.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2951) Laminin_II PF06009.12 ORY49322.1 - 7.1 6.6 19.6 3.5 7.6 4.3 3.3 1 1 1 3 3 3 0 Laminin Domain II DUF5344 PF17279.2 ORY49322.1 - 7.8 7.2 19.1 0.32 11.6 2.1 4.2 3 3 2 5 5 5 0 Family of unknown function (DUF5344) HIP1_clath_bdg PF16515.5 ORY49322.1 - 8.7 7.0 25.2 0.11 13.1 6.2 3.7 2 2 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Flu_NS2 PF00601.19 ORY49323.1 - 0.55 10.6 14.5 3.9 7.8 2.1 3.7 2 1 0 2 2 2 0 Influenza non-structural protein (NS2) Spc7 PF08317.11 ORY49323.1 - 6.4 5.6 43.2 5.1 5.9 26.3 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein GAS PF13851.6 ORY49323.1 - 7.8 5.8 47.6 0.34 10.2 18.4 3.6 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding LRR_6 PF13516.6 ORY49324.1 - 1.8e-24 83.7 18.7 0.0017 18.3 0.0 9.2 9 0 0 9 9 9 6 Leucine Rich repeat LRR_4 PF12799.7 ORY49324.1 - 1.8e-09 37.7 7.9 0.026 14.9 0.4 5.6 5 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY49324.1 - 6.1e-07 29.1 6.2 21 6.1 0.0 8.0 9 0 0 9 9 9 2 Leucine Rich Repeat LRR_8 PF13855.6 ORY49324.1 - 8.3e-06 25.5 11.8 2.6 7.9 0.3 6.3 5 3 1 6 6 6 4 Leucine rich repeat Wza_C PF18412.1 ORY49324.1 - 0.11 12.3 0.1 13 5.6 0.1 2.7 2 0 0 2 2 2 0 Outer-membrane lipoprotein Wza C-terminal domain Pox_A_type_inc PF04508.12 ORY49326.1 - 0.00025 20.7 0.6 0.00066 19.4 0.6 1.8 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat Gln-synt_N_2 PF16952.5 ORY49326.1 - 0.019 14.8 0.0 0.041 13.7 0.0 1.4 1 1 0 1 1 1 0 Glutamine synthetase N-terminal domain HMG_CoA_synt_N PF01154.17 ORY49326.1 - 0.066 13.1 0.1 0.073 12.9 0.1 1.2 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase N terminal HIRAN PF08797.11 ORY49326.1 - 0.093 12.7 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 HIRAN domain Fasciclin PF02469.22 ORY49327.1 - 5.9e-19 68.5 0.2 8.8e-10 38.9 0.0 2.7 2 0 0 2 2 2 2 Fasciclin domain NOA36 PF06524.12 ORY49327.1 - 0.15 11.3 6.2 0.33 10.2 6.2 1.5 1 0 0 1 1 1 0 NOA36 protein CDC45 PF02724.14 ORY49327.1 - 1.7 6.8 12.5 2.6 6.2 12.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 ORY49327.1 - 2.1 6.4 7.9 3.1 5.8 7.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CENP-B_dimeris PF09026.10 ORY49327.1 - 4.9 7.6 10.7 10 6.6 10.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain YL1 PF05764.13 ORY49327.1 - 9.7 6.2 20.3 29 4.7 20.3 1.8 1 1 0 1 1 1 0 YL1 nuclear protein AAA_18 PF13238.6 ORY49328.1 - 1.4e-09 38.6 0.0 2.2e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 ORY49328.1 - 2.1e-09 37.7 0.0 2.5e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 ORY49328.1 - 3.5e-07 30.5 0.0 4.7e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 ORY49328.1 - 4.8e-06 26.5 0.0 6e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase Rad17 PF03215.15 ORY49328.1 - 0.00041 20.3 0.0 0.0022 18.0 0.0 1.9 1 1 1 2 2 2 1 Rad17 P-loop domain Viral_helicase1 PF01443.18 ORY49328.1 - 0.0016 18.2 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.6 ORY49328.1 - 0.0027 18.1 0.6 0.014 15.8 0.6 1.9 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 ORY49328.1 - 0.0035 17.1 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CbiA PF01656.23 ORY49328.1 - 0.0082 16.2 0.0 0.011 15.8 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 ORY49328.1 - 0.01 16.2 0.1 0.012 16.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ORY49328.1 - 0.043 14.1 0.0 0.089 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ORY49328.1 - 0.075 13.1 0.0 0.4 10.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF1611 PF07755.11 ORY49328.1 - 0.088 12.1 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain CLP1_P PF16575.5 ORY49328.1 - 0.099 12.4 0.0 4 7.2 0.0 2.1 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Cytidylate_kin PF02224.18 ORY49328.1 - 0.1 12.3 0.2 0.31 10.7 0.0 1.8 2 0 0 2 2 2 0 Cytidylate kinase ParA PF10609.9 ORY49328.1 - 0.1 12.0 0.4 0.19 11.1 0.4 1.4 1 1 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase tRNA_lig_kinase PF08303.11 ORY49328.1 - 0.11 12.6 0.1 0.16 12.0 0.1 1.5 1 1 0 1 1 1 0 tRNA ligase kinase domain AAA_5 PF07728.14 ORY49328.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) dNK PF01712.19 ORY49328.1 - 0.11 12.3 1.1 3.7 7.4 0.2 2.1 1 1 1 2 2 2 0 Deoxynucleoside kinase RNA_helicase PF00910.22 ORY49328.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 ORY49328.1 - 0.15 12.3 0.1 0.25 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 ORY49328.1 - 0.19 12.1 0.2 0.46 10.9 0.2 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 ORY49328.1 - 0.22 11.2 0.3 5.8 6.5 0.1 2.2 2 0 0 2 2 2 0 Thymidylate kinase Glyco_transf_64 PF09258.10 ORY49329.1 - 1.7e-41 142.1 1.0 1.3e-31 109.8 0.0 3.1 3 1 0 3 3 3 2 Glycosyl transferase family 64 domain CENP-R PF06729.12 ORY49329.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 Kinetochore component, CENP-R DUF3211 PF11485.8 ORY49329.1 - 0.12 12.6 0.3 10 6.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3211) Gag_MA PF01140.19 ORY49329.1 - 1.6 8.5 4.6 1.3 8.8 0.1 2.6 3 0 0 3 3 3 0 Matrix protein (MA), p15 TPT PF03151.16 ORY49330.1 - 3.4e-18 66.0 9.0 4.9e-18 65.5 9.0 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORY49330.1 - 8.8e-09 35.7 7.6 8.8e-09 35.7 7.6 2.7 3 1 0 3 3 3 1 EamA-like transporter family DUF1700 PF08006.11 ORY49330.1 - 2.5 7.6 17.7 0.048 13.2 9.9 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1700) DUF3493 PF11998.8 ORY49331.1 - 0.13 12.4 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Low psii accumulation1 / Rep27 Glyco_transf_64 PF09258.10 ORY49332.1 - 3.4e-50 170.6 0.1 5.4e-50 170.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain QLQ PF08880.11 ORY49332.1 - 0.037 13.8 0.7 0.086 12.6 0.7 1.6 1 0 0 1 1 1 0 QLQ Glycos_transf_2 PF00535.26 ORY49333.1 - 0.061 13.1 0.0 21 4.9 0.0 3.1 3 0 0 3 3 3 0 Glycosyl transferase family 2 Glyco_transf_64 PF09258.10 ORY49334.1 - 1.4e-14 54.0 0.1 2.4e-14 53.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 64 domain BTB_2 PF02214.22 ORY49335.1 - 2.4e-09 37.4 0.0 6.4e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain DUF4132 PF13569.6 ORY49335.1 - 0.094 12.5 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4132) SDH_alpha PF03313.15 ORY49336.1 - 2e-91 306.3 1.7 2.5e-91 305.9 1.7 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 ORY49336.1 - 5.7e-36 124.2 1.8 2.7e-26 92.8 0.1 2.9 2 1 1 3 3 3 2 Serine dehydratase beta chain SDH_beta PF03315.15 ORY49337.1 - 1.2e-36 126.4 0.1 1.6e-36 126.0 0.1 1.2 1 0 0 1 1 1 1 Serine dehydratase beta chain SDH_alpha PF03313.15 ORY49338.1 - 3.5e-78 262.9 0.6 1.6e-77 260.7 0.6 1.8 1 1 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.15 ORY49338.1 - 2.5e-08 34.4 0.0 8.2e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 Serine dehydratase beta chain MmgE_PrpD PF03972.14 ORY49338.1 - 0.55 8.7 5.1 0.77 8.2 4.9 1.4 1 1 0 1 1 1 0 MmgE/PrpD family TMEM51 PF15345.6 ORY49339.1 - 0.0071 16.2 0.2 0.012 15.5 0.2 1.4 1 0 0 1 1 1 1 Transmembrane protein 51 PP2C PF00481.21 ORY49340.1 - 3.5e-37 128.5 0.0 1.9e-36 126.0 0.0 2.2 1 1 1 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 ORY49340.1 - 0.0014 18.4 0.1 0.0059 16.3 0.1 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C DnaJ-X PF14308.6 ORY49341.1 - 4.1e-28 98.3 0.0 1.5e-27 96.4 0.0 1.8 1 1 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 ORY49341.1 - 5.6e-12 45.6 2.5 2e-10 40.6 2.5 2.6 1 1 0 1 1 1 1 DnaJ domain PAN_4 PF14295.6 ORY49342.1 - 0.049 13.5 1.3 0.13 12.1 1.3 1.8 1 0 0 1 1 1 0 PAN domain Ephrin_rec_like PF07699.13 ORY49343.1 - 0.00018 21.2 4.2 0.00018 21.2 4.2 2.4 2 1 0 2 2 2 1 Putative ephrin-receptor like OpuAC PF04069.12 ORY49343.1 - 0.0022 17.6 0.0 0.043 13.4 0.0 2.3 2 0 0 2 2 2 1 Substrate binding domain of ABC-type glycine betaine transport system IL6 PF00489.17 ORY49343.1 - 0.06 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Interleukin-6/G-CSF/MGF family Leuk-A4-hydro_C PF09127.11 ORY49344.1 - 0.05 13.7 0.0 0.074 13.1 0.0 1.2 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal DUF3522 PF12036.8 ORY49344.1 - 0.099 12.9 0.0 0.11 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) OpuAC PF04069.12 ORY49345.1 - 6.6e-08 32.5 0.0 8.6e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Substrate binding domain of ABC-type glycine betaine transport system FeoC PF09012.10 ORY49345.1 - 0.077 13.1 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 FeoC like transcriptional regulator Pkinase PF00069.25 ORY49346.1 - 1.4e-66 224.6 0.0 1.7e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY49346.1 - 5e-35 121.0 0.0 6.4e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY49346.1 - 2.8e-08 33.4 0.0 3.7e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY49346.1 - 4.1e-05 22.5 0.0 6.9e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 ORY49346.1 - 0.018 14.4 0.1 0.03 13.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY49346.1 - 0.024 14.6 0.1 0.043 13.7 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY49346.1 - 0.061 12.3 0.1 0.083 11.8 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 ORY49347.1 - 1.2e-47 162.5 0.0 1.8e-47 161.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY49347.1 - 3.3e-26 92.1 0.0 5e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY49347.1 - 0.0013 18.2 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY49347.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ORY49347.1 - 0.099 12.3 0.0 13 5.4 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 ORY49347.1 - 0.13 12.2 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 ORY49348.1 - 8.7e-64 215.4 0.0 1.1e-63 215.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY49348.1 - 5.7e-33 114.3 0.0 7.6e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY49348.1 - 4.6e-07 29.0 0.0 9.3e-07 27.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY49348.1 - 1.5e-05 24.5 0.0 0.00014 21.3 0.0 2.0 1 1 0 2 2 2 1 Kinase-like FANCM-MHF_bd PF16783.5 ORY49348.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 FANCM to MHF binding domain Haspin_kinase PF12330.8 ORY49348.1 - 0.14 11.1 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 ORY49348.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 ORY49348.1 - 0.19 11.1 0.0 0.46 9.8 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5323 PF17257.2 ORY49349.1 - 2 8.3 7.8 0.42 10.5 2.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5323) TFIIA PF03153.13 ORY49349.1 - 8.6 6.2 16.9 11 5.9 16.9 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mg_trans_NIPA PF05653.14 ORY49350.1 - 8.8e-66 222.0 8.4 1.1e-65 221.6 8.4 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORY49350.1 - 4e-08 33.5 17.1 1.4e-07 31.8 5.8 3.2 3 0 0 3 3 3 2 EamA-like transporter family Glyco_transf_34 PF05637.12 ORY49352.1 - 2.2e-14 53.8 7.7 1.1e-11 45.0 7.7 2.1 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Nucleotid_trans PF03407.16 ORY49352.1 - 0.0015 18.5 1.0 0.0023 17.9 1.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF273 PF03314.14 ORY49352.1 - 0.048 13.2 0.0 0.074 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF273 HECT_2 PF09814.9 ORY49353.1 - 2e-19 69.7 0.9 2.3e-19 69.5 0.9 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding JIP_LZII PF16471.5 ORY49353.1 - 0.087 13.0 0.9 0.2 11.8 0.9 1.6 1 0 0 1 1 1 0 JNK-interacting protein leucine zipper II Zn_clus PF00172.18 ORY49354.1 - 0.0011 19.0 8.8 0.0016 18.6 8.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PNP_UDP_1 PF01048.20 ORY49355.1 - 5.6e-47 160.0 1.2 6.7e-47 159.7 1.2 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily SAM_1 PF00536.30 ORY49356.1 - 4.5e-13 49.4 0.1 7.1e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 ORY49356.1 - 2.7e-10 40.2 0.0 4.6e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Podoplanin PF05808.11 ORY49356.1 - 7.7e-06 26.1 0.7 1.7e-05 25.0 0.7 1.5 1 0 0 1 1 1 1 Podoplanin SKG6 PF08693.10 ORY49356.1 - 0.00021 20.6 2.0 0.00051 19.4 2.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SAM_Ste50p PF09235.10 ORY49356.1 - 0.0017 18.5 0.1 0.0029 17.8 0.1 1.3 1 0 0 1 1 1 1 Ste50p, sterile alpha motif TMEM51 PF15345.6 ORY49356.1 - 0.002 18.0 1.2 0.002 18.0 1.2 2.1 1 1 1 2 2 1 1 Transmembrane protein 51 TMEM154 PF15102.6 ORY49356.1 - 0.003 17.4 1.0 0.0055 16.6 0.0 1.9 2 0 0 2 2 2 1 TMEM154 protein family DUF4690 PF15756.5 ORY49356.1 - 0.0052 17.4 0.7 0.0052 17.4 0.7 2.3 2 0 0 2 2 2 1 Small Novel Rich in Cartilage Amnionless PF14828.6 ORY49356.1 - 0.011 14.5 1.3 0.023 13.5 0.4 1.7 1 1 1 2 2 2 0 Amnionless Mid2 PF04478.12 ORY49356.1 - 0.015 15.2 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Rax2 PF12768.7 ORY49356.1 - 0.018 14.5 0.2 0.018 14.5 0.2 1.8 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Adeno_E3_CR2 PF02439.15 ORY49356.1 - 0.028 14.2 0.6 0.052 13.3 0.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Glycophorin_A PF01102.18 ORY49356.1 - 0.047 13.9 4.2 0.077 13.2 0.0 2.6 3 0 0 3 3 3 0 Glycophorin A DUF2207 PF09972.9 ORY49356.1 - 0.088 11.6 0.2 0.17 10.6 0.0 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) SSP160 PF06933.11 ORY49356.1 - 0.097 10.9 9.9 0.15 10.3 9.9 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF2407_C PF13373.6 ORY49356.1 - 0.1 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 DUF2407 C-terminal domain Syndecan PF01034.20 ORY49356.1 - 0.2 11.6 0.2 0.2 11.6 0.2 2.1 2 0 0 2 2 1 0 Syndecan domain SR-25 PF10500.9 ORY49356.1 - 0.43 10.1 9.1 0.06 13.0 5.1 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein FeoB_associated PF12669.7 ORY49356.1 - 0.49 10.8 1.7 0.89 10.0 1.7 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein EphA2_TM PF14575.6 ORY49356.1 - 1.3 10.0 0.0 1.3 10.0 0.0 2.4 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain MtrF PF09472.10 ORY49356.1 - 3.1 7.3 4.9 6.5 6.2 4.9 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) MBOAT PF03062.19 ORY49357.1 - 5.4e-30 104.9 16.7 5.4e-30 104.9 16.7 2.1 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 ORY49357.1 - 1.7e-05 25.0 0.4 7.1e-05 23.0 0.4 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ABC_tran_CTD PF16326.5 ORY49357.1 - 0.058 13.7 0.5 0.096 12.9 0.5 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF2852 PF11014.8 ORY49358.1 - 1.2 9.3 3.0 1.7 8.8 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2852) FeS_assembly_P PF01883.19 ORY49359.1 - 3.9e-12 46.1 0.0 8e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein LRR_8 PF13855.6 ORY49360.1 - 4.6e-20 71.1 49.2 5.3e-10 38.9 7.1 4.3 2 1 4 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 ORY49360.1 - 4.3e-12 46.0 36.9 0.00049 20.4 2.7 5.5 1 1 6 7 7 7 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY49360.1 - 2.8e-07 30.2 37.1 0.19 12.4 0.6 8.2 6 2 1 7 7 7 3 Leucine Rich Repeat F-box PF00646.33 ORY49360.1 - 4.3e-05 23.3 0.1 0.00012 21.9 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY49360.1 - 6.3e-05 22.8 0.3 0.00019 21.3 0.3 1.9 1 0 0 1 1 1 1 F-box-like LRR_9 PF14580.6 ORY49360.1 - 0.63 9.5 6.4 3.2 7.2 0.4 2.6 1 1 1 2 2 2 0 Leucine-rich repeat FNIP PF05725.12 ORY49360.1 - 1.3 9.3 13.6 3.5 7.9 0.4 4.7 2 2 2 4 4 4 0 FNIP Repeat Voltage_CLC PF00654.20 ORY49361.1 - 4.7e-84 282.6 18.1 4.7e-84 282.6 18.1 2.1 2 1 1 3 3 3 1 Voltage gated chloride channel Phage_holin_2_1 PF04971.12 ORY49361.1 - 6.2 6.9 5.7 1.7 8.7 0.1 2.9 3 0 0 3 3 3 0 Bacteriophage P21 holin S Lyase_1 PF00206.20 ORY49364.1 - 9.9e-84 281.4 1.2 3.5e-54 184.3 1.1 3.1 1 1 1 2 2 2 2 Lyase FumaraseC_C PF10415.9 ORY49364.1 - 4.2e-26 91.1 0.1 1.5e-25 89.4 0.0 2.0 2 0 0 2 2 2 1 Fumarase C C-terminus Ecl1 PF12855.7 ORY49365.1 - 0.00032 21.9 25.2 0.0015 19.7 25.1 1.9 1 1 0 1 1 1 1 ECL1/2/3 zinc binding proteins XPA_C PF05181.12 ORY49366.1 - 1.4e-10 41.0 0.0 2.6e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 XPA protein C-terminus LPD29 PF18847.1 ORY49367.1 - 0.16 13.0 0.0 0.24 12.3 0.0 1.4 1 0 0 1 1 1 0 Large polyvalent protein associated domain 29 Exo_endo_phos PF03372.23 ORY49370.1 - 2.6e-18 66.4 0.2 2e-17 63.5 0.2 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.6 ORY49370.1 - 6.2e-09 35.5 4.8 6.2e-09 35.5 4.8 2.2 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY49370.1 - 1.8e-07 31.3 5.1 0.00044 20.6 0.4 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) AAA PF00004.29 ORY49371.1 - 1.6e-48 164.5 0.0 4.7e-32 111.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY49371.1 - 1.3e-09 38.7 0.1 0.00052 20.4 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 ORY49371.1 - 7.2e-09 35.8 0.0 0.00035 20.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY49371.1 - 1.1e-08 35.5 0.1 0.0093 16.2 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_lid_3 PF17862.1 ORY49371.1 - 2.4e-08 33.6 0.0 4.7e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 ORY49371.1 - 8.8e-08 32.0 0.0 0.02 14.7 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ORY49371.1 - 2.2e-07 31.1 0.2 0.0006 20.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 ORY49371.1 - 9.7e-07 28.3 0.5 0.0087 15.3 0.1 2.8 2 1 1 3 3 3 2 TIP49 P-loop domain CDC48_2 PF02933.17 ORY49371.1 - 2.3e-06 27.3 0.2 3.9e-05 23.4 0.0 3.0 3 0 0 3 3 3 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.21 ORY49371.1 - 3.6e-06 26.5 0.4 0.0061 16.0 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.12 ORY49371.1 - 6.8e-06 26.1 0.8 0.044 13.7 0.0 3.6 3 1 1 4 4 4 2 NACHT domain AAA_33 PF13671.6 ORY49371.1 - 7.9e-06 26.1 0.0 0.068 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 ORY49371.1 - 1.2e-05 25.3 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 ORY49371.1 - 1.2e-05 25.1 0.0 0.05 13.3 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 ORY49371.1 - 1.4e-05 25.4 0.0 0.11 12.9 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_24 PF13479.6 ORY49371.1 - 1.7e-05 24.7 1.5 0.083 12.6 0.1 2.8 2 2 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 ORY49371.1 - 2.7e-05 23.9 0.0 0.088 12.5 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_7 PF12775.7 ORY49371.1 - 3.9e-05 23.2 0.1 0.046 13.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_18 PF13238.6 ORY49371.1 - 4.7e-05 24.0 0.1 0.067 13.7 0.0 3.1 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.22 ORY49371.1 - 8.2e-05 21.9 0.0 0.41 9.8 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_30 PF13604.6 ORY49371.1 - 0.00012 21.9 0.1 0.21 11.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 ORY49371.1 - 0.00023 21.7 0.3 1.2 9.7 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PhoH PF02562.16 ORY49371.1 - 0.00035 20.1 0.0 0.83 9.1 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_25 PF13481.6 ORY49371.1 - 0.00051 19.7 2.4 2.2 7.8 0.0 3.6 3 1 1 4 4 4 1 AAA domain AAA_14 PF13173.6 ORY49371.1 - 0.00061 19.8 0.0 0.46 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 ORY49371.1 - 0.00089 18.7 0.1 0.067 12.5 0.1 2.5 2 0 0 2 2 2 1 KaiC Parvo_NS1 PF01057.17 ORY49371.1 - 0.0017 17.5 0.0 1.3 8.0 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 ORY49371.1 - 0.003 17.5 0.1 3 7.7 0.0 3.1 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 ORY49371.1 - 0.0051 17.1 0.0 5.2 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 ORY49371.1 - 0.0054 16.0 0.4 0.75 9.0 0.1 2.7 2 1 1 3 3 3 1 Uncharacterized conserved protein (DUF2075) Cytidylate_kin PF02224.18 ORY49371.1 - 0.0099 15.6 0.2 2.1 8.0 0.1 2.6 2 0 0 2 2 2 1 Cytidylate kinase AAA_3 PF07726.11 ORY49371.1 - 0.011 15.6 0.0 0.45 10.4 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CPT PF07931.12 ORY49371.1 - 0.011 15.6 0.0 0.091 12.6 0.0 2.2 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_11 PF13086.6 ORY49371.1 - 0.012 15.4 0.0 0.69 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORY49371.1 - 0.013 15.9 1.4 0.53 10.6 0.2 2.9 3 0 0 3 3 2 0 AAA domain AAA_29 PF13555.6 ORY49371.1 - 0.014 15.1 0.2 0.88 9.4 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain ResIII PF04851.15 ORY49371.1 - 0.017 15.2 0.0 4.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TniB PF05621.11 ORY49371.1 - 0.017 14.6 0.1 6 6.2 0.1 3.1 3 1 0 3 3 2 0 Bacterial TniB protein T2SSE PF00437.20 ORY49371.1 - 0.033 13.2 0.0 7.1 5.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein DAP3 PF10236.9 ORY49371.1 - 0.044 12.9 0.0 9.6 5.3 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 CDC48_N PF02359.18 ORY49371.1 - 0.046 13.9 0.0 0.27 11.4 0.0 2.4 3 0 0 3 3 1 0 Cell division protein 48 (CDC48), N-terminal domain Zeta_toxin PF06414.12 ORY49371.1 - 0.052 12.8 0.1 1.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 ORY49371.1 - 0.059 13.8 0.8 9.7 6.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.6 ORY49371.1 - 0.063 13.8 0.2 2.8 8.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 ORY49371.1 - 0.098 12.4 0.1 23 4.7 0.0 3.6 3 1 1 4 4 4 0 DEAD/DEAH box helicase Vps4_C PF09336.10 ORY49371.1 - 0.15 12.1 0.0 0.64 10.1 0.0 2.1 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AFG1_ATPase PF03969.16 ORY49371.1 - 0.19 10.6 0.0 4.7 6.0 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase HMGL-like PF00682.19 ORY49372.1 - 1.3e-20 74.1 0.4 3.7e-19 69.3 0.4 2.0 1 1 0 1 1 1 1 HMGL-like UCH PF00443.29 ORY49374.1 - 5.9e-14 52.2 0.0 6.8e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PseudoU_synth_2 PF00849.22 ORY49375.1 - 1.3e-16 61.1 0.0 1.9e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 ORY49375.1 - 0.035 13.8 0.6 0.076 12.7 0.2 1.8 2 0 0 2 2 2 0 S4 domain DUF2369 PF10179.9 ORY49375.1 - 0.17 12.3 0.0 0.41 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) CDO_I PF05995.12 ORY49376.1 - 0.033 13.5 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Cysteine dioxygenase type I VLPT PF07122.11 ORY49376.1 - 0.034 13.9 0.3 0.094 12.5 0.3 1.7 1 0 0 1 1 1 0 Variable length PCR target protein (VLPT) Cupin_2 PF07883.11 ORY49376.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Cupin domain Response_reg PF00072.24 ORY49377.1 - 0.008 16.3 0.1 0.021 15.0 0.1 1.7 1 1 0 1 1 1 1 Response regulator receiver domain PARP PF00644.20 ORY49378.1 - 4.4e-19 68.9 0.2 1.9e-15 57.0 0.0 2.4 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Thioredoxin PF00085.20 ORY49378.1 - 1.9e-05 24.6 0.0 4.8e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin SPRY PF00622.28 ORY49378.1 - 2e-05 24.7 0.1 4.4e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 SPRY domain BAG PF02179.16 ORY49378.1 - 0.00015 22.1 0.4 0.00051 20.4 0.0 2.1 2 0 0 2 2 2 1 BAG domain Exotox-A_cataly PF09009.10 ORY49378.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Exotoxin A catalytic DUF2205 PF10224.9 ORY49378.1 - 0.081 12.9 0.5 2.7 8.0 0.2 2.8 2 0 0 2 2 2 0 Short coiled-coil protein Thioredoxin_8 PF13905.6 ORY49378.1 - 0.082 13.2 0.1 1.1 9.7 0.1 2.9 2 1 0 3 3 3 0 Thioredoxin-like DUF2726 PF10881.8 ORY49378.1 - 0.11 12.4 0.2 18 5.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2726) DivIVA PF05103.13 ORY49378.1 - 0.25 11.5 2.7 0.57 10.3 2.7 1.6 1 0 0 1 1 1 0 DivIVA protein Wbp11 PF09429.10 ORY49380.1 - 2.7e-12 46.9 23.2 5e-12 46.1 23.2 1.4 1 0 0 1 1 1 1 WW domain binding protein 11 Cwf_Cwc_15 PF04889.12 ORY49380.1 - 0.14 11.9 20.6 0.3 10.8 19.3 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TRIQK PF15168.6 ORY49380.1 - 0.22 11.4 1.5 0.46 10.4 1.5 1.5 1 0 0 1 1 1 0 Triple QxxK/R motif-containing protein family TFIIA PF03153.13 ORY49380.1 - 1 9.3 18.7 1.9 8.4 11.2 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Voltage_CLC PF00654.20 ORY49381.1 - 1.4e-69 235.0 21.7 2.1e-69 234.5 21.7 1.1 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 ORY49381.1 - 9.3e-05 22.8 0.0 0.014 15.9 0.0 2.4 2 0 0 2 2 2 2 CBS domain LRR_8 PF13855.6 ORY49382.1 - 4.8e-33 112.7 60.3 1.1e-07 31.4 0.9 8.0 5 2 2 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 ORY49382.1 - 1.5e-27 95.1 52.4 0.00012 22.4 1.5 9.0 5 2 3 9 9 9 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY49382.1 - 1.2e-08 34.3 58.5 1.9 9.3 0.1 14.7 15 1 0 15 15 15 7 Leucine Rich Repeat F-box PF00646.33 ORY49382.1 - 0.0015 18.3 0.3 0.0062 16.4 0.3 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY49382.1 - 0.016 15.1 0.1 0.072 13.0 0.1 2.2 1 0 0 1 1 1 0 F-box-like DUF2585 PF10755.9 ORY49383.1 - 0.07 12.9 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2585) Fungal_trans PF04082.18 ORY49384.1 - 0.02 13.9 0.0 0.025 13.6 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY49385.1 - 9.4e-05 22.5 7.4 0.00014 21.9 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMEM215 PF15746.5 ORY49385.1 - 0.052 13.0 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 TMEM215 family Trehalase PF01204.18 ORY49386.1 - 6.3e-118 394.8 0.1 3.9e-87 293.2 0.0 3.2 2 1 1 3 3 3 3 Trehalase Trehalase_Ca-bi PF07492.11 ORY49386.1 - 1.8e-14 53.1 0.1 3.3e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ANF_receptor PF01094.28 ORY49387.1 - 4.5e-17 62.2 0.0 6.8e-11 41.9 0.0 2.0 1 1 1 2 2 2 2 Receptor family ligand binding region Zn_clus PF00172.18 ORY49388.1 - 3e-06 27.2 5.3 5.1e-06 26.5 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY49392.1 - 0.0042 16.2 0.0 0.0085 15.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PseudoU_synth_2 PF00849.22 ORY49393.1 - 1.1e-27 97.1 0.0 1.9e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Dynamin_N PF00350.23 ORY49394.1 - 2.8e-28 99.1 0.0 3.4e-28 98.8 0.0 1.0 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 ORY49394.1 - 1.1e-05 25.4 0.1 2.7e-05 24.2 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 ORY49394.1 - 0.038 13.8 0.1 0.067 13.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 ORY49394.1 - 0.066 13.7 0.1 0.076 13.5 0.1 1.4 1 1 0 1 1 1 0 ABC transporter MALT1_Ig PF18703.1 ORY49394.1 - 0.16 11.9 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 MALT1 Ig-like domain Fungal_trans PF04082.18 ORY49395.1 - 1.3e-10 40.8 0.3 3.7e-10 39.3 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain CPSase_L_D2 PF02786.17 ORY49397.1 - 6.7e-77 257.7 0.4 1.2e-76 256.9 0.4 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 ORY49397.1 - 3e-45 153.3 0.4 8.3e-45 151.9 0.1 1.9 2 0 0 2 2 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 ORY49397.1 - 1.9e-33 114.8 0.0 6.5e-33 113.1 0.0 2.0 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain PCC_BT PF18140.1 ORY49397.1 - 5.3e-27 94.7 0.1 1.4e-26 93.3 0.1 1.8 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain Biotin_lipoyl PF00364.22 ORY49397.1 - 2.9e-17 62.3 3.3 4.2e-17 61.7 1.3 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 ORY49397.1 - 2.6e-10 40.2 0.0 6.4e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 ORY49397.1 - 9.4e-10 38.2 0.3 1.7e-05 24.5 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.22 ORY49397.1 - 2.3e-09 37.0 0.1 5.1e-09 35.9 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 ORY49397.1 - 2.7e-06 28.0 1.5 0.004 17.8 0.1 3.3 4 0 0 4 4 2 2 HlyD family secretion protein RimK PF08443.11 ORY49397.1 - 0.00014 21.5 0.0 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 ORY49397.1 - 0.00048 20.2 0.1 0.0018 18.3 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain HlyD_D23 PF16576.5 ORY49397.1 - 0.0012 18.1 0.2 0.011 15.0 0.0 2.2 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion GARS_A PF01071.19 ORY49397.1 - 0.0015 18.3 0.1 0.0049 16.7 0.1 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NQRA PF05896.11 ORY49397.1 - 0.0075 15.7 0.4 0.012 15.0 0.4 1.3 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RnfC_N PF13375.6 ORY49397.1 - 0.018 15.0 0.6 0.077 13.0 0.1 2.3 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain ATP-grasp_5 PF13549.6 ORY49397.1 - 0.021 14.3 0.5 0.085 12.3 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain GCV_H PF01597.19 ORY49397.1 - 0.031 14.1 0.1 0.097 12.6 0.1 1.8 1 0 0 1 1 1 0 Glycine cleavage H-protein SLT_beta PF02258.16 ORY49397.1 - 0.076 13.1 0.4 0.26 11.3 0.1 2.0 2 0 0 2 2 2 0 Shiga-like toxin beta subunit PTS_EIIA_1 PF00358.20 ORY49397.1 - 0.12 12.1 2.5 12 5.6 0.1 2.9 2 1 1 3 3 3 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Carboxyl_trans PF01039.22 ORY49398.1 - 3.7e-156 520.6 0.3 4.3e-155 517.1 0.3 2.0 1 1 0 1 1 1 1 Carboxyl transferase domain FLILHELTA PF10306.9 ORY49401.1 - 2.1e-16 60.1 0.0 3e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 ORY49401.1 - 1.8e-05 25.2 0.1 4.4e-05 24.0 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) DUF3405 PF11885.8 ORY49402.1 - 1.7e-15 56.7 2.7 2.7e-08 32.9 0.1 3.0 1 1 1 3 3 3 3 Protein of unknown function (DUF3405) DUF3405 PF11885.8 ORY49403.1 - 8e-24 84.1 0.1 1.5e-17 63.4 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3405) Zn_clus PF00172.18 ORY49407.1 - 8.7e-09 35.4 10.1 8.7e-09 35.4 10.1 1.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4637 PF15470.6 ORY49407.1 - 0.05 13.3 2.8 0.055 13.2 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Fungal_trans PF04082.18 ORY49408.1 - 0.0027 16.8 0.0 0.0047 16.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain LPD5 PF18799.1 ORY49409.1 - 0.16 12.4 2.6 0.24 11.8 2.6 1.2 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 5 LRR_4 PF12799.7 ORY49410.1 - 8.1e-15 54.7 29.8 9.7e-05 22.7 0.3 7.0 4 2 5 9 9 9 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORY49410.1 - 0.009 15.5 8.3 0.4 10.2 0.2 3.3 1 1 2 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 ORY49410.1 - 0.016 15.0 2.8 0.016 15.0 2.8 6.1 2 2 7 9 9 9 0 Leucine rich repeat Zn_clus PF00172.18 ORY49414.1 - 0.00029 20.9 12.7 0.00058 19.9 12.7 1.6 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XPG_N PF00752.17 ORY49415.1 - 1.8e-30 105.4 0.0 3.2e-30 104.6 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XRN_N PF03159.18 ORY49415.1 - 0.075 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus XPG_I PF00867.18 ORY49417.1 - 5.9e-27 93.9 0.0 1.8e-26 92.3 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 ORY49417.1 - 5.7e-06 26.0 0.1 1.6e-05 24.5 0.0 1.9 2 1 0 2 2 2 1 XPG domain containing Eno-Rase_FAD_bd PF07055.12 ORY49417.1 - 0.017 15.5 0.0 0.055 13.9 0.0 1.8 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain NUDIX PF00293.28 ORY49417.1 - 0.59 10.2 2.9 1.1 9.3 2.9 1.5 1 0 0 1 1 1 0 NUDIX domain HALZ PF02183.18 ORY49418.1 - 0.026 14.8 0.1 0.026 14.8 0.1 7.5 8 0 0 8 8 8 0 Homeobox associated leucine zipper Med9 PF07544.13 ORY49418.1 - 0.15 12.2 0.0 0.15 12.2 0.0 4.9 4 1 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 WD40 PF00400.32 ORY49420.1 - 3e-23 81.7 6.4 0.00017 22.3 0.5 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY49420.1 - 1.8e-05 25.0 0.0 4.4 7.7 0.0 4.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY49420.1 - 0.048 12.6 0.1 5.6 5.8 0.0 3.0 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ORY49420.1 - 0.13 11.5 0.0 2.3 7.4 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain DUF3865 PF12981.7 ORY49420.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3865) MRP-L28 PF09812.9 ORY49421.1 - 5.4e-07 29.9 0.1 8.6e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 RsbU_N PF08673.10 ORY49421.1 - 0.098 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain GRAM PF02893.20 ORY49422.1 - 0.0019 18.1 0.2 0.0036 17.2 0.2 1.5 1 0 0 1 1 1 1 GRAM domain Fungal_trans PF04082.18 ORY49424.1 - 5.4e-11 42.0 0.1 8.8e-11 41.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY49425.1 - 6.3e-06 26.2 20.7 0.0017 18.4 8.9 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY49425.1 - 0.00042 19.4 0.2 0.00069 18.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_2 PF12796.7 ORY49427.1 - 1.2e-20 73.8 0.8 1.9e-06 28.4 0.1 3.7 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) VPS9 PF02204.18 ORY49427.1 - 1.5e-19 70.1 0.0 3.9e-19 68.8 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_4 PF13637.6 ORY49427.1 - 7.6e-16 58.3 3.0 0.003 18.1 0.1 5.4 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY49427.1 - 6.4e-15 53.8 1.7 0.001 19.3 0.0 5.8 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 ORY49427.1 - 7.5e-10 38.9 2.9 0.011 16.1 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY49427.1 - 1.5e-09 37.8 6.9 0.0019 18.6 0.1 6.5 6 0 0 6 6 6 2 Ankyrin repeat PX PF00787.24 ORY49427.1 - 2e-07 31.0 0.4 5.1e-07 29.7 0.1 1.8 2 0 0 2 2 2 1 PX domain zf-RING_9 PF13901.6 ORY49427.1 - 0.16 11.9 2.5 1.8 8.5 0.0 2.9 2 1 1 3 3 3 0 Putative zinc-RING and/or ribbon Peptidase_C65 PF10275.9 ORY49427.1 - 0.24 10.8 2.4 0.47 9.9 2.4 1.4 1 0 0 1 1 1 0 Peptidase C65 Otubain Vps5 PF09325.10 ORY49428.1 - 0.00021 20.9 0.4 0.00024 20.7 0.4 1.1 1 0 0 1 1 1 1 Vps5 C terminal like Spc7 PF08317.11 ORY49428.1 - 0.0063 15.4 0.9 0.0089 14.9 0.9 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein PSII_Pbs27 PF13326.6 ORY49428.1 - 0.018 15.4 2.7 0.022 15.1 2.7 1.2 1 0 0 1 1 1 0 Photosystem II Pbs27 WD40 PF00400.32 ORY49429.1 - 8.1e-28 96.1 24.6 6.9e-07 29.9 0.7 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY49429.1 - 8.8e-13 48.4 0.1 0.0084 16.4 0.0 4.8 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY49429.1 - 1.3e-06 27.7 5.4 0.11 11.4 0.0 4.7 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORY49429.1 - 1.3e-06 27.4 0.1 0.029 13.0 0.1 3.2 1 1 1 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.11 ORY49429.1 - 1.8e-05 24.7 0.1 0.021 14.7 0.0 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A SARS_X4 PF08779.10 ORY49429.1 - 0.024 14.9 0.0 0.42 10.9 0.0 2.5 3 0 0 3 3 3 0 SARS coronavirus X4 like Pkinase PF00069.25 ORY49430.1 - 1.6e-39 135.9 0.0 1.8e-19 70.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY49430.1 - 3.1e-14 52.9 0.0 2.1e-09 37.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Aconitase PF00330.20 ORY49430.1 - 0.045 12.8 0.6 0.065 12.2 0.6 1.1 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) Presenilin PF01080.17 ORY49430.1 - 1.4 7.6 3.7 2.1 7.0 3.7 1.2 1 0 0 1 1 1 0 Presenilin Zn_clus PF00172.18 ORY49431.1 - 0.00039 20.5 11.8 0.00062 19.8 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phospholip_A2_3 PF09056.11 ORY49433.1 - 0.00018 22.1 2.6 0.00018 22.1 2.6 2.1 1 1 1 2 2 2 1 Prokaryotic phospholipase A2 PLA2G12 PF06951.11 ORY49433.1 - 0.056 13.3 2.7 0.086 12.7 2.7 1.3 1 0 0 1 1 1 0 Group XII secretory phospholipase A2 precursor (PLA2G12) DUF1353 PF07087.11 ORY49433.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) EzrA PF06160.12 ORY49434.1 - 0.026 12.7 2.5 0.03 12.5 2.5 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Ribosomal_S2 PF00318.20 ORY49434.1 - 0.044 13.0 0.7 0.062 12.5 0.7 1.2 1 0 0 1 1 1 0 Ribosomal protein S2 RNA_pol PF00940.19 ORY49434.1 - 0.15 10.9 0.1 0.18 10.6 0.1 1.1 1 0 0 1 1 1 0 DNA-dependent RNA polymerase DciA PF05258.12 ORY49435.1 - 0.071 13.5 0.1 0.12 12.8 0.1 1.6 1 1 0 1 1 1 0 Dna[CI] antecedent, DciA Metallophos PF00149.28 ORY49437.1 - 8.7e-37 127.6 0.4 1.3e-36 127.0 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORY49437.1 - 0.00011 22.5 0.0 0.0002 21.7 0.0 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 ORY49437.1 - 0.008 15.8 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Metallophos_2 PF12850.7 ORY49437.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain cwf21 PF08312.12 ORY49437.1 - 0.3 11.3 1.3 0.59 10.3 1.3 1.5 1 0 0 1 1 1 0 cwf21 domain RhoGEF PF00621.20 ORY49439.1 - 1.7e-22 80.5 5.7 5.9e-21 75.5 5.7 2.2 1 1 0 1 1 1 1 RhoGEF domain MFS_1 PF07690.16 ORY49440.1 - 7.7e-40 136.9 55.9 9.2e-29 100.5 11.8 3.3 3 1 0 3 3 3 3 Major Facilitator Superfamily Nucleos_tra2_C PF07662.13 ORY49441.1 - 5.4e-60 202.8 4.3 5.4e-60 202.8 4.3 2.7 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 ORY49441.1 - 2.7e-19 69.6 3.1 2.7e-19 69.6 3.1 2.9 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.14 ORY49441.1 - 0.00015 22.0 7.5 0.00015 22.0 7.5 3.6 3 0 0 3 3 3 1 Nucleoside recognition SNF2_N PF00176.23 ORY49442.1 - 7.5e-69 232.1 0.0 1.4e-68 231.2 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.6 ORY49442.1 - 6.7e-07 29.5 8.3 6.7e-07 29.5 8.3 2.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORY49442.1 - 1.3e-05 25.0 5.7 1.3e-05 25.0 5.7 2.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 ORY49442.1 - 1.5e-05 25.3 0.0 3.9e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HD PF01966.22 ORY49442.1 - 2.7e-05 24.4 0.2 8.3e-05 22.8 0.2 1.9 1 0 0 1 1 1 1 HD domain zf-C3HC4_2 PF13923.6 ORY49442.1 - 8.4e-05 22.3 7.9 8.4e-05 22.3 7.9 2.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY49442.1 - 0.0001 22.2 6.9 0.0001 22.2 6.9 3.1 2 1 0 2 2 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 ORY49442.1 - 0.00014 22.1 17.1 0.00027 21.1 7.5 2.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ORY49442.1 - 0.00026 20.9 2.8 0.00026 20.9 2.8 2.7 2 1 1 3 3 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY49442.1 - 0.00098 19.0 8.0 0.00098 19.0 8.0 3.0 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 ORY49442.1 - 0.0011 18.9 7.9 0.0011 18.9 7.9 2.8 2 0 0 2 2 2 1 PHD-finger zf-ANAPC11 PF12861.7 ORY49442.1 - 0.01 15.9 3.7 0.01 15.9 3.7 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 ORY49442.1 - 0.75 9.5 19.2 0.027 14.1 5.2 2.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 ORY49442.1 - 4.5 7.1 20.9 0.016 14.9 4.9 4.0 3 0 0 3 3 3 0 RING-like zinc finger TPR_7 PF13176.6 ORY49442.1 - 5.3 7.3 6.7 3.1 8.0 0.0 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat Chromo PF00385.24 ORY49443.1 - 0.00032 20.5 18.3 3.7 7.5 0.2 5.2 5 0 0 5 5 5 5 Chromo (CHRromatin Organisation MOdifier) domain DUF4914 PF16260.5 ORY49443.1 - 0.021 13.0 0.1 17 3.3 0.0 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF4914) RIB43A PF05914.12 ORY49443.1 - 0.043 12.6 0.0 54 2.4 0.0 4.2 5 0 0 5 5 5 0 RIB43A RCR PF12273.8 ORY49443.1 - 0.076 13.7 1.1 30 5.3 0.7 4.1 1 1 1 2 2 2 0 Chitin synthesis regulation, resistance to Congo red ABC_membrane PF00664.23 ORY49444.1 - 3e-69 233.7 35.2 2.9e-38 132.1 12.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY49444.1 - 1.7e-48 164.6 0.0 6.5e-25 88.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY49444.1 - 3.3e-10 39.8 6.3 0.00025 20.5 0.1 4.5 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY49444.1 - 1.1e-07 31.5 0.9 0.00025 20.7 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY49444.1 - 1.3e-07 31.7 0.1 0.0074 16.4 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 ORY49444.1 - 2.3e-05 24.4 0.3 0.2 11.4 0.1 4.1 5 0 0 5 5 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORY49444.1 - 5.2e-05 23.7 0.2 0.26 11.6 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 ORY49444.1 - 0.00015 22.4 0.2 0.027 15.0 0.1 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 ORY49444.1 - 0.00019 21.6 1.7 0.13 12.3 0.0 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_22 PF13401.6 ORY49444.1 - 0.00034 20.9 0.1 0.28 11.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 ORY49444.1 - 0.00068 19.6 0.0 0.053 13.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Dynamin_N PF00350.23 ORY49444.1 - 0.0023 18.0 2.8 0.27 11.3 0.2 2.7 2 0 0 2 2 2 1 Dynamin family AAA_7 PF12775.7 ORY49444.1 - 0.0031 17.1 0.1 2.7 7.5 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_30 PF13604.6 ORY49444.1 - 0.0082 15.9 0.2 1.8 8.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ORY49444.1 - 0.012 15.6 2.6 0.41 10.5 0.0 2.8 3 0 0 3 3 2 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 ORY49444.1 - 0.012 15.0 0.7 4.2 6.6 0.2 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 ORY49444.1 - 0.016 15.1 2.2 3.8 7.4 0.1 2.9 3 0 0 3 3 3 0 NTPase NB-ARC PF00931.22 ORY49444.1 - 0.016 14.4 0.8 5 6.2 0.0 3.1 3 0 0 3 3 3 0 NB-ARC domain Roc PF08477.13 ORY49444.1 - 0.018 15.3 0.2 7.6 6.8 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 ORY49444.1 - 0.018 14.7 0.2 0.51 9.9 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 ORY49444.1 - 0.021 14.4 0.1 0.65 9.5 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain T2SSE PF00437.20 ORY49444.1 - 0.023 13.8 0.0 4.1 6.4 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_5 PF07728.14 ORY49444.1 - 0.032 14.2 1.7 18 5.3 0.0 4.0 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 ORY49444.1 - 0.035 13.7 1.7 1.4 8.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain Ploopntkinase3 PF18751.1 ORY49444.1 - 0.041 13.8 0.1 9.8 6.0 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 PduV-EutP PF10662.9 ORY49444.1 - 0.053 13.3 0.2 35 4.1 0.0 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Pox_A32 PF04665.12 ORY49444.1 - 0.12 11.9 0.2 2.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein RNA_helicase PF00910.22 ORY49444.1 - 0.12 12.7 0.1 27 5.2 0.0 2.9 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 ORY49444.1 - 0.16 11.7 0.5 17 5.1 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_15 PF13175.6 ORY49444.1 - 0.38 10.4 0.5 2.6 7.7 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 ORY49444.1 - 0.59 10.3 4.3 8.4 6.5 0.1 3.7 4 0 0 4 4 3 0 AAA domain NDUF_B8 PF05821.11 ORY49445.1 - 1e-05 25.5 0.2 3.5e-05 23.8 0.2 1.7 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Na_H_Exchanger PF00999.21 ORY49446.1 - 6.5e-67 226.0 34.0 8.1e-67 225.6 34.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Phage_holin_2_3 PF16080.5 ORY49446.1 - 3.1 7.6 8.3 1.7 8.4 0.1 3.5 3 0 0 3 3 3 0 Bacteriophage holin family HP1 MFS_1 PF07690.16 ORY49447.1 - 4.5e-45 154.1 55.1 1.8e-42 145.5 39.6 3.8 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 ORY49447.1 - 1.4e-22 79.9 20.2 1.4e-22 79.9 20.2 2.0 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY49447.1 - 4e-08 32.6 13.3 4e-08 32.6 13.3 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter G-patch PF01585.23 ORY49448.1 - 2.7e-12 46.4 2.9 5.8e-12 45.3 2.9 1.5 1 0 0 1 1 1 1 G-patch domain FHA PF00498.26 ORY49448.1 - 4.4e-09 36.6 0.0 1.5e-08 34.8 0.0 2.0 1 0 0 1 1 1 1 FHA domain G-patch_2 PF12656.7 ORY49448.1 - 5.1e-07 29.7 0.3 1e-06 28.7 0.3 1.6 1 0 0 1 1 1 1 G-patch domain Yop-YscD_cpl PF16697.5 ORY49448.1 - 0.0056 17.0 0.2 0.033 14.5 0.0 2.5 2 1 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain PsaN PF05479.11 ORY49448.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) OCRE PF17780.1 ORY49448.1 - 0.18 11.8 0.6 0.44 10.6 0.1 1.8 2 0 0 2 2 2 0 OCRE domain COX4_pro PF03626.14 ORY49449.1 - 0.47 10.9 0.1 0.47 10.9 0.1 3.1 3 1 0 3 3 3 0 Prokaryotic Cytochrome C oxidase subunit IV DUF3810 PF12725.7 ORY49449.1 - 3.7 6.8 6.9 0.28 10.5 0.9 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3810) Actin PF00022.19 ORY49450.1 - 3.8e-127 424.3 0.0 3.4e-126 421.1 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 ORY49450.1 - 0.12 11.2 0.0 0.92 8.3 0.0 2.3 1 1 0 1 1 1 0 MreB/Mbl protein DUF3134 PF11332.8 ORY49451.1 - 0.0067 16.7 4.5 0.0067 16.7 4.5 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3134) Med10 PF09748.9 ORY49451.1 - 0.15 12.1 5.4 0.41 10.6 0.0 3.1 3 1 0 3 3 3 0 Transcription factor subunit Med10 of Mediator complex V_ATPase_I PF01496.19 ORY49451.1 - 0.38 8.6 7.7 0.41 8.5 7.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2009 PF09418.10 ORY49451.1 - 1.1 8.3 6.6 0.8 8.7 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2009) MIEAP PF16026.5 ORY49451.1 - 1.3 9.2 8.7 4.6 7.4 0.2 2.3 2 0 0 2 2 2 0 Mitochondria-eating protein MPS2 PF17060.5 ORY49451.1 - 4.4 6.5 13.7 0.22 10.8 7.1 2.1 2 1 0 2 2 2 0 Monopolar spindle protein 2 Mt_ATP-synt_B PF05405.14 ORY49451.1 - 6.1 6.4 14.9 0.076 12.6 1.4 3.1 2 1 1 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Gb3_synth PF04572.12 ORY49452.1 - 2.4e-23 82.7 0.0 4.6e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.15 ORY49452.1 - 4.8e-15 56.0 0.1 1.4e-14 54.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Gb3_synth PF04572.12 ORY49453.1 - 8.7e-52 174.7 2.2 5.7e-30 104.2 0.6 2.9 3 0 0 3 3 3 2 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.15 ORY49453.1 - 2.8e-25 88.8 0.0 2.7e-11 43.9 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase sugar-binding region containing DXD motif TFR_dimer PF04253.15 ORY49453.1 - 0.054 13.6 0.6 0.23 11.6 0.1 2.3 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain TcdA_TcdB PF12919.7 ORY49453.1 - 0.058 12.7 0.1 3.8 6.7 0.0 2.2 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Gly_transf_sug PF04488.15 ORY49454.1 - 4.5e-12 46.4 0.0 8.6e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Gb3_synth PF04572.12 ORY49454.1 - 6.1e-11 42.6 0.0 1e-09 38.7 0.0 2.1 2 0 0 2 2 2 1 Alpha 1,4-glycosyltransferase conserved region Gb3_synth PF04572.12 ORY49455.1 - 1.5e-40 138.4 0.0 1.5e-23 83.4 0.0 3.8 2 1 0 2 2 2 2 Alpha 1,4-glycosyltransferase conserved region Gly_transf_sug PF04488.15 ORY49455.1 - 1.1e-25 90.1 0.0 6.3e-12 46.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 ORY49455.1 - 0.047 13.0 0.1 1.2 8.4 0.1 2.2 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain E1_4HB PF16191.5 ORY49455.1 - 0.066 13.4 0.1 2.7 8.2 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 four-helix bundle Gly_transf_sug PF04488.15 ORY49457.1 - 3e-12 47.0 0.0 6e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Gb3_synth PF04572.12 ORY49457.1 - 5.7e-11 42.7 0.8 3.1e-10 40.3 0.1 2.2 2 0 0 2 2 2 1 Alpha 1,4-glycosyltransferase conserved region TPPK_C PF12555.8 ORY49457.1 - 0.019 15.0 0.6 0.049 13.7 0.6 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal 7TM_GPCR_Str PF10326.9 ORY49458.1 - 0.004 16.6 1.2 0.005 16.2 1.2 1.1 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str SAC3_GANP PF03399.16 ORY49459.1 - 3e-23 82.7 0.3 6.6e-21 75.0 0.3 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 ORY49459.1 - 7.6e-06 26.0 0.0 3.6e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family GDPD PF03009.17 ORY49460.1 - 6.1e-10 39.3 0.0 7.3e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Apt1 PF10351.9 ORY49461.1 - 0.0033 16.3 9.6 0.0045 15.9 9.6 1.2 1 0 0 1 1 1 1 Golgi-body localisation protein domain Membralin PF09746.9 ORY49461.1 - 0.22 10.5 3.3 0.38 9.7 3.3 1.3 1 0 0 1 1 1 0 Tumour-associated protein Kei1 PF08552.11 ORY49461.1 - 0.37 10.7 12.1 0.69 9.8 12.1 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 GREB1 PF15782.5 ORY49461.1 - 0.73 6.9 12.2 0.97 6.5 12.2 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF572 PF04502.13 ORY49461.1 - 0.86 9.2 10.7 1.2 8.7 10.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ecl1 PF12855.7 ORY49461.1 - 0.92 10.7 42.4 2.2 9.4 35.6 2.5 2 0 0 2 2 2 0 ECL1/2/3 zinc binding proteins Tmemb_cc2 PF10267.9 ORY49461.1 - 0.97 8.5 11.6 2 7.5 11.6 1.5 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SOG2 PF10428.9 ORY49461.1 - 2.2 7.4 34.1 0.032 13.4 25.8 1.8 2 0 0 2 2 2 0 RAM signalling pathway protein GDPD PF03009.17 ORY49462.1 - 1.9e-28 99.9 0.0 8.6e-27 94.5 0.0 2.0 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 ORY49462.1 - 0.0029 18.0 0.0 0.0067 16.9 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF4996 PF16387.5 ORY49462.1 - 0.17 12.4 0.0 2.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function GDPD PF03009.17 ORY49463.1 - 4.6e-23 82.3 0.0 2.9e-22 79.7 0.0 1.9 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Herpes_UL56 PF04534.12 ORY49464.1 - 1.5 8.3 7.7 2 7.8 7.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL56 protein Fungal_trans PF04082.18 ORY49465.1 - 9.1e-05 21.6 0.3 0.00013 21.1 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY49467.1 - 2.2e-08 34.1 20.0 5.3e-05 23.3 8.5 2.2 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0014 PF03649.13 ORY49468.1 - 2.1e-29 102.6 3.4 4.3e-19 68.8 0.0 2.3 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0014) LRR_8 PF13855.6 ORY49468.1 - 1.1e-19 69.9 43.5 2.1e-09 37.0 5.9 6.3 3 3 5 8 8 8 6 Leucine rich repeat LRR_4 PF12799.7 ORY49468.1 - 2.1e-15 56.6 44.3 5.4e-05 23.5 2.2 8.0 3 2 4 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY49468.1 - 8.3e-06 25.7 37.1 3.6 8.5 0.0 11.1 8 2 2 10 10 10 2 Leucine Rich Repeat LRR_9 PF14580.6 ORY49468.1 - 9.1 5.7 15.5 19 4.7 0.4 4.2 2 2 1 4 4 4 0 Leucine-rich repeat Sulfatase PF00884.23 ORY49470.1 - 3.6e-21 75.8 0.0 4.6e-18 65.7 0.0 2.3 1 1 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 ORY49470.1 - 0.00012 22.3 0.0 0.00022 21.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Glyco_hydro_26 PF02156.15 ORY49471.1 - 6e-09 35.7 1.5 8.5e-09 35.3 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Glyco_hydro_26 PF02156.15 ORY49472.1 - 1.4e-08 34.6 2.6 2.6e-08 33.7 2.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Ion_trans PF00520.31 ORY49473.1 - 1.1e-17 64.1 29.9 1.7e-16 60.2 29.9 2.1 1 1 0 1 1 1 1 Ion transport protein zf-LITAF-like PF10601.9 ORY49473.1 - 0.0083 16.4 2.6 0.0083 16.4 2.6 2.7 4 0 0 4 4 4 1 LITAF-like zinc ribbon domain CytochromB561_N PF09786.9 ORY49473.1 - 0.011 14.8 0.4 0.011 14.8 0.4 2.0 2 1 1 3 3 3 0 Cytochrome B561, N terminal Pap_E4 PF02711.14 ORY49473.1 - 0.86 10.6 5.7 1.9 9.5 0.6 2.6 2 0 0 2 2 2 0 E4 protein DUF1634 PF07843.11 ORY49473.1 - 5.9 7.0 9.8 4.3 7.5 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1634) DUF3421 PF11901.8 ORY49474.1 - 5.5e-19 68.3 4.8 9.1e-13 48.2 0.1 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) DUF3421 PF11901.8 ORY49477.1 - 2.3e-10 40.5 0.0 3.1e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3421) DUF3421 PF11901.8 ORY49478.1 - 3e-20 72.3 0.3 9e-08 32.1 0.0 3.4 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) LapA_dom PF06305.11 ORY49479.1 - 0.022 14.6 0.0 0.03 14.1 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Phage_holin_2_4 PF16082.5 ORY49479.1 - 0.045 13.5 0.1 0.062 13.0 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like DAG1 PF05454.11 ORY49479.1 - 0.12 11.8 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) GDI PF00996.18 ORY49480.1 - 1.5e-205 682.8 0.3 1.7e-205 682.6 0.3 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.24 ORY49480.1 - 0.00028 20.3 0.0 0.00038 19.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase ITAM PF02189.15 ORY49480.1 - 0.17 12.4 0.5 1.2 9.7 0.3 2.7 2 0 0 2 2 2 0 Immunoreceptor tyrosine-based activation motif Aldedh PF00171.22 ORY49481.1 - 1.1e-130 436.3 0.0 1.3e-130 436.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PAP_assoc PF03828.19 ORY49482.1 - 0.00065 19.9 0.1 0.0024 18.1 0.1 2.0 1 0 0 1 1 1 1 Cid1 family poly A polymerase Methyltransf_31 PF13847.6 ORY49486.1 - 1.4e-11 44.5 0.0 2.2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY49486.1 - 8.2e-07 28.7 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ORY49486.1 - 4.6e-06 27.2 0.0 1.2e-05 26.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.16 ORY49486.1 - 2.8e-05 23.5 0.0 4.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase PrmA PF06325.13 ORY49486.1 - 0.00033 20.2 0.0 0.00054 19.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 ORY49486.1 - 0.0015 19.2 0.0 0.0036 17.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain rRNA_methylase PF06962.12 ORY49486.1 - 0.0015 18.5 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 Putative rRNA methylase UPF0020 PF01170.18 ORY49486.1 - 0.0052 16.5 0.0 0.009 15.7 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 S4_2 PF13275.6 ORY49486.1 - 0.0062 16.3 0.5 0.017 15.0 0.5 1.6 1 0 0 1 1 1 1 S4 domain Methyltransf_23 PF13489.6 ORY49486.1 - 0.0066 16.3 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY49486.1 - 0.019 15.7 0.0 0.046 14.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PseudoU_synth_2 PF00849.22 ORY49486.1 - 0.028 14.5 0.0 0.061 13.4 0.0 1.5 1 1 0 1 1 1 0 RNA pseudouridylate synthase Methyltransf_32 PF13679.6 ORY49486.1 - 0.06 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PPR_2 PF13041.6 ORY49490.1 - 1.1e-08 35.2 0.0 1.4e-06 28.4 0.0 3.0 2 1 2 4 4 4 2 PPR repeat family PPR_3 PF13812.6 ORY49490.1 - 0.034 14.2 0.1 0.97 9.6 0.1 2.8 1 1 2 3 3 3 0 Pentatricopeptide repeat domain PPR_2 PF13041.6 ORY49491.1 - 1.8e-11 44.0 0.2 7.3e-11 42.1 0.1 1.8 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.20 ORY49491.1 - 6e-08 32.4 0.0 0.0051 17.0 0.0 2.9 3 0 0 3 3 3 2 PPR repeat PPR_1 PF12854.7 ORY49491.1 - 1.5e-07 31.0 0.2 0.013 15.2 0.0 2.5 2 0 0 2 2 2 2 PPR repeat PPR_3 PF13812.6 ORY49491.1 - 7.9e-05 22.7 0.3 0.00014 21.8 0.3 1.5 1 1 0 1 1 1 1 Pentatricopeptide repeat domain RPM2 PF08579.11 ORY49491.1 - 0.13 12.6 0.1 0.36 11.2 0.1 1.7 1 1 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) RHH_5 PF07878.11 ORY49492.1 - 0.12 12.3 0.1 0.2 11.6 0.1 1.3 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 FANCI_S1-cap PF14674.6 ORY49492.1 - 0.21 11.7 0.1 0.59 10.3 0.0 1.7 2 0 0 2 2 2 0 FANCI solenoid 1 cap MTHFR PF02219.17 ORY49493.1 - 8.3e-108 360.0 0.0 1e-107 359.7 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase PIN_9 PF18477.1 ORY49493.1 - 0.16 12.3 0.0 0.54 10.6 0.0 1.8 2 0 0 2 2 2 0 PIN like domain MTHFR PF02219.17 ORY49494.1 - 1.4e-98 329.8 0.0 1.8e-98 329.4 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase MBOAT PF03062.19 ORY49495.1 - 5.6e-30 104.9 19.2 9.5e-30 104.1 19.2 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF3216 PF11505.8 ORY49497.1 - 0.051 13.8 0.1 2.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) Internalin_N PF12354.8 ORY49497.1 - 0.39 10.8 3.9 0.96 9.6 0.0 3.3 3 0 0 3 3 3 0 Bacterial adhesion/invasion protein N terminal AflR PF08493.10 ORY49499.1 - 0.5 9.8 4.6 0.59 9.6 4.6 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein Phosphoesterase PF04185.14 ORY49500.1 - 7.7e-12 45.1 0.1 9.9e-12 44.7 0.1 1.1 1 0 0 1 1 1 1 Phosphoesterase family PTR2 PF00854.21 ORY49501.1 - 4.7e-48 164.0 6.4 1.4e-36 126.2 2.7 3.1 2 1 0 2 2 2 2 POT family Pkinase PF00069.25 ORY49502.1 - 7.4e-16 58.3 0.0 8.9e-16 58.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY49502.1 - 1.9e-05 24.1 0.0 2.4e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase CsgE PF10627.9 ORY49503.1 - 0.12 12.7 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Curli assembly protein CsgE Alpha_kinase PF02816.18 ORY49504.1 - 6.2e-29 101.4 2.0 1.1e-28 100.6 1.0 1.8 1 1 1 2 2 2 1 Alpha-kinase family GvpG PF05120.12 ORY49504.1 - 0.1 12.6 0.1 0.19 11.8 0.1 1.4 1 0 0 1 1 1 0 Gas vesicle protein G Peptidase_M1 PF01433.20 ORY49506.1 - 3.1e-44 151.1 1.3 5.4e-43 147.1 2.0 2.1 2 0 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 ORY49506.1 - 1.4e-37 129.7 0.0 1.4e-35 123.1 0.0 2.3 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 ORY49506.1 - 5.2e-22 78.8 0.0 6.1e-21 75.3 0.0 2.2 2 0 0 2 2 2 1 ERAP1-like C-terminal domain LRR_4 PF12799.7 ORY49506.1 - 6.8e-07 29.5 14.4 0.0022 18.4 0.4 4.4 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY49506.1 - 0.35 10.7 12.7 7.7 6.4 6.4 3.4 2 1 1 3 3 3 0 Leucine rich repeat Abhydrolase_1 PF00561.20 ORY49507.1 - 1.5e-14 54.3 0.0 1.6e-13 50.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY49507.1 - 6.4e-11 43.3 0.4 3.1e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY49507.1 - 4.9e-09 35.8 0.0 7.9e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Hydrolase_4 PF12146.8 ORY49508.1 - 5.2e-06 25.9 0.0 1e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY49508.1 - 1.2e-05 25.1 0.1 0.0016 18.2 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Cutinase PF01083.22 ORY49508.1 - 0.033 14.2 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Cutinase Mg_trans_NIPA PF05653.14 ORY49510.1 - 2.7e-28 98.9 14.3 2.2e-16 59.8 2.7 2.3 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 ORY49510.1 - 2.6e-06 27.6 2.7 2.6e-06 27.6 2.7 3.7 4 1 0 4 4 4 1 EamA-like transporter family TMEM234 PF10639.9 ORY49510.1 - 0.00016 21.7 0.3 0.00042 20.3 0.0 1.8 2 0 0 2 2 2 1 Putative transmembrane family 234 DUF2304 PF10066.9 ORY49510.1 - 1.7 8.9 5.5 5.5 7.3 1.0 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) NTP_transf_9 PF04248.12 ORY49512.1 - 0.08 12.8 0.1 6.6 6.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF427) Fer4_22 PF17179.4 ORY49513.1 - 0.13 13.1 0.1 0.61 11.0 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain adh_short_C2 PF13561.6 ORY49516.1 - 5.4e-54 183.2 1.4 1.2e-52 178.8 1.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY49516.1 - 6.1e-50 169.4 0.9 1.1e-48 165.2 0.9 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY49516.1 - 1.3e-13 51.3 0.1 2.1e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 KR domain Hydrolase_4 PF12146.8 ORY49517.1 - 1.7e-12 47.1 0.0 3.1e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 ORY49517.1 - 2.2e-09 37.3 0.8 9.3e-09 35.3 0.8 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY49517.1 - 6.2e-08 33.5 1.3 1.6e-07 32.2 0.7 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 ORY49517.1 - 0.0072 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Peptidase_M17 PF00883.21 ORY49518.1 - 1.8e-93 313.3 0.2 2.9e-93 312.6 0.2 1.3 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Pdase_M17_N2 PF18295.1 ORY49518.1 - 3.5e-13 49.9 0.7 6.5e-13 49.0 0.7 1.5 1 0 0 1 1 1 1 M17 aminopeptidase N-terminal domain 2 HMG_box PF00505.19 ORY49519.1 - 3e-12 46.8 0.3 5.5e-12 45.9 0.3 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY49519.1 - 0.0027 18.3 0.1 0.006 17.1 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain DUF4236 PF14020.6 ORY49519.1 - 0.032 14.8 0.3 0.032 14.8 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4236) GalP_UDP_tr_C PF02744.17 ORY49520.1 - 3.2e-57 192.9 0.0 5.7e-57 192.1 0.0 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.22 ORY49520.1 - 6.4e-52 176.7 0.1 1.3e-51 175.7 0.1 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF4921 PF16268.5 ORY49520.1 - 1.4e-06 27.4 1.7 0.0019 17.1 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4921) DcpS_C PF11969.8 ORY49520.1 - 8.2e-05 23.1 0.0 0.00025 21.5 0.0 1.8 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 ORY49520.1 - 0.00022 21.9 2.1 0.0063 17.2 0.3 2.5 2 1 0 2 2 2 1 HIT domain TRAP-gamma PF07074.12 ORY49520.1 - 0.016 14.8 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF1870 PF08965.10 ORY49520.1 - 0.11 12.5 0.0 21 5.2 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1870) ScsC_N PF18312.1 ORY49521.1 - 0.037 13.9 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 Copper resistance protein ScsC N-terminal domain BRCT PF00533.26 ORY49522.1 - 4.7e-53 177.5 0.0 3.8e-09 36.8 0.0 5.2 5 0 0 5 5 5 5 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 ORY49522.1 - 4e-20 71.5 9.6 0.0016 18.3 0.1 5.3 5 0 0 5 5 5 5 twin BRCT domain Vta1 PF04652.16 ORY49522.1 - 0.00014 21.8 2.7 3.2 7.7 0.1 3.5 3 0 0 3 3 3 3 Vta1 like PBP1_TM PF14812.6 ORY49522.1 - 0.009 16.4 23.6 5 7.6 0.0 4.4 4 0 0 4 4 4 3 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_60s PF00428.19 ORY49522.1 - 0.016 15.8 13.2 0.016 15.8 13.2 5.3 4 1 0 4 4 4 0 60s Acidic ribosomal protein MraZ PF02381.18 ORY49522.1 - 0.034 14.1 0.2 67 3.6 0.2 4.4 4 0 0 4 4 4 0 MraZ protein, putative antitoxin-like PIP5K PF01504.18 ORY49522.1 - 0.21 10.8 0.2 35 3.5 0.0 2.9 3 0 0 3 3 3 0 Phosphatidylinositol-4-phosphate 5-Kinase FAM176 PF14851.6 ORY49522.1 - 0.38 10.4 26.9 1.3 8.7 0.9 4.3 4 0 0 4 4 4 0 FAM176 family DUF4431 PF14485.6 ORY49522.1 - 0.54 10.1 2.0 85 3.1 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4431) RPN2_C PF18004.1 ORY49522.1 - 7 6.5 19.8 6.9 6.6 1.7 4.0 4 0 0 4 4 4 0 26S proteasome regulatory subunit RPN2 C-terminal domain C2 PF00168.30 ORY49523.1 - 3e-08 33.9 0.0 6.4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain EF-hand_6 PF13405.6 ORY49523.1 - 0.065 13.2 0.4 2.8 8.1 0.2 3.2 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 ORY49523.1 - 0.24 11.0 1.4 2.3 7.9 0.5 2.8 3 0 0 3 3 3 0 EF hand TPR_12 PF13424.6 ORY49524.1 - 5.8e-18 65.0 13.2 8.5e-08 32.4 4.7 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 ORY49524.1 - 2.9e-12 45.7 17.5 0.027 14.6 0.2 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 ORY49524.1 - 7.8e-12 44.4 3.9 0.014 15.4 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY49524.1 - 4.9e-11 41.9 15.1 0.015 15.5 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORY49524.1 - 5.9e-11 42.2 4.3 2 9.4 0.0 6.4 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY49524.1 - 1.4e-10 40.6 23.0 4e-05 23.3 0.1 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY49524.1 - 6.6e-10 38.5 8.9 0.0014 18.5 0.5 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY49524.1 - 2.7e-07 30.3 5.1 1.2e-06 28.2 2.1 2.5 1 1 2 3 3 3 2 MalT-like TPR region TPR_9 PF13371.6 ORY49524.1 - 1.2e-05 25.3 1.0 0.51 10.5 0.0 4.5 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY49524.1 - 5.5e-05 23.7 0.2 5.5 7.7 0.0 4.9 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY49524.1 - 7e-05 23.2 8.3 0.0015 19.0 1.3 4.2 1 1 3 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY49524.1 - 0.00015 22.2 7.2 14 6.6 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY49524.1 - 0.00051 20.2 12.1 0.27 11.5 2.6 4.3 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 ORY49524.1 - 0.0058 16.4 4.2 4.3 7.0 0.0 3.9 2 2 2 4 4 4 1 26S proteasome subunit RPN7 Hira PF07569.11 ORY49524.1 - 0.036 13.8 0.2 0.073 12.8 0.2 1.5 1 0 0 1 1 1 0 TUP1-like enhancer of split TPR_3 PF07720.12 ORY49524.1 - 0.06 13.4 4.9 12 6.0 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 ORY49524.1 - 0.093 13.0 0.1 1e+02 3.5 0.0 3.8 4 0 0 4 4 3 0 PPR repeat TPR_17 PF13431.6 ORY49524.1 - 0.17 12.3 5.6 40 4.9 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY49524.1 - 0.18 11.5 3.1 1.1e+02 2.6 0.0 4.4 4 0 0 4 4 4 0 TPR repeat DUF4810 PF16068.5 ORY49524.1 - 1.6 9.4 4.3 19 5.9 0.1 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF4810) LAG1-DNAbind PF09271.11 ORY49526.1 - 0.045 14.4 0.8 0.075 13.7 0.2 1.6 2 0 0 2 2 2 0 LAG1, DNA binding RAB3GAP2_C PF14656.6 ORY49527.1 - 4.7e-17 61.5 0.2 6.3e-14 51.1 0.1 2.2 2 0 0 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit C-terminus RAB3GAP2_N PF14655.6 ORY49527.1 - 5e-16 59.0 0.0 1.7e-15 57.2 0.0 1.8 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus SET PF00856.28 ORY49529.1 - 3.9e-05 24.1 0.0 0.00017 22.0 0.0 1.9 2 0 0 2 2 2 1 SET domain EF-hand_4 PF12763.7 ORY49529.1 - 0.13 12.2 0.1 0.48 10.4 0.1 2.0 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Lipase_GDSL_2 PF13472.6 ORY49530.1 - 3.9e-22 79.5 0.0 6e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY49530.1 - 8e-15 55.3 0.0 1.2e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 ORY49531.1 - 1e-22 81.4 0.0 1.9e-22 80.5 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY49531.1 - 2.4e-17 63.6 0.0 2.9e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 ORY49531.1 - 0.0074 16.4 0.0 3.8 7.6 0.0 3.0 3 0 0 3 3 3 1 GDSL-like Lipase/Acylhydrolase family Pkinase PF00069.25 ORY49532.1 - 1.3e-67 228.0 0.0 1.5e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY49532.1 - 1.7e-37 129.2 0.0 1.9e-37 128.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY49532.1 - 2.2e-08 33.8 0.0 2.8e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY49532.1 - 6.7e-08 31.9 0.6 1e-07 31.3 0.6 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY49532.1 - 2.8e-07 30.1 0.1 4.7e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORY49532.1 - 8.1e-06 25.6 0.2 1.2e-05 25.0 0.2 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 ORY49532.1 - 5.8e-05 23.1 0.3 0.0001 22.3 0.3 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY49532.1 - 0.0011 18.6 0.1 0.0016 18.1 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 ORY49532.1 - 0.08 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase MRP-S25 PF13741.6 ORY49533.1 - 3.1e-17 62.9 0.1 3.5e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 ORY49533.1 - 0.012 15.9 0.2 0.021 15.1 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S23 MRP-S25 PF13741.6 ORY49534.1 - 3.1e-17 62.9 0.1 3.5e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 ORY49534.1 - 0.012 15.9 0.2 0.021 15.1 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal protein S23 KA1 PF02149.19 ORY49535.1 - 4.7e-08 32.7 0.1 8.5e-08 31.9 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Pkinase PF00069.25 ORY49536.1 - 2.3e-69 233.7 0.0 2.9e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY49536.1 - 5.1e-38 130.8 0.0 7.1e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY49536.1 - 7.1e-09 35.4 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY49536.1 - 2.1e-07 30.5 0.0 4e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY49536.1 - 3e-06 26.4 0.1 5.5e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 ORY49536.1 - 4e-06 26.6 0.1 9.5e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 ORY49536.1 - 5.4e-05 23.2 0.3 5.4e-05 23.2 0.3 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY49536.1 - 0.0028 17.3 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 ORY49536.1 - 0.041 12.7 0.0 0.06 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FANCM-MHF_bd PF16783.5 ORY49536.1 - 0.11 12.6 1.8 0.2 11.8 1.8 1.4 1 0 0 1 1 1 0 FANCM to MHF binding domain adh_short_C2 PF13561.6 ORY49537.1 - 3.4e-38 131.5 0.9 3.9e-38 131.3 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY49537.1 - 1.3e-34 119.3 0.7 1.7e-34 119.0 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 ORY49537.1 - 6.7e-08 32.6 1.0 1.6e-07 31.4 1.0 1.6 1 1 0 1 1 1 1 KR domain ApbA PF02558.16 ORY49537.1 - 0.13 11.9 0.1 0.22 11.2 0.1 1.5 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ACOX PF01756.19 ORY49538.1 - 1.2e-33 116.2 0.0 1.8e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 ORY49538.1 - 1.3e-17 63.7 0.1 2.4e-17 62.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 ORY49538.1 - 1.3e-05 25.8 0.0 2.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal LST1 PF05083.13 ORY49539.1 - 0.00039 20.6 0.1 0.00078 19.7 0.1 1.5 1 0 0 1 1 1 1 LST-1 protein DUF4448 PF14610.6 ORY49539.1 - 0.001 18.9 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Herpes_gE PF02480.16 ORY49539.1 - 0.015 14.1 0.1 0.023 13.5 0.1 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.6 ORY49539.1 - 0.064 13.2 6.3 0.023 14.6 2.1 2.3 2 1 0 2 2 2 0 TMEM154 protein family Cadherin_C_2 PF16492.5 ORY49539.1 - 0.065 14.0 0.6 0.24 12.2 0.6 1.9 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal MLANA PF14991.6 ORY49539.1 - 0.08 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A DUF5305 PF17231.2 ORY49539.1 - 0.098 12.0 0.8 1.2 8.5 0.0 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5305) Orf78 PF06024.12 ORY49539.1 - 0.21 11.9 0.1 0.48 10.8 0.1 1.7 1 1 0 1 1 1 0 Orf78 (ac78) WSC PF01822.19 ORY49539.1 - 1.2 9.3 6.1 3.9 7.7 6.1 1.9 1 0 0 1 1 1 0 WSC domain DUF4690 PF15756.5 ORY49540.1 - 0.029 14.9 1.3 0.029 14.9 1.3 2.9 1 1 2 3 3 3 0 Small Novel Rich in Cartilage DUF4021 PF13213.6 ORY49540.1 - 0.95 9.5 6.9 0.39 10.7 3.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4021) T4SS_CagC PF16943.5 ORY49541.1 - 0.13 12.5 0.0 0.39 10.9 0.0 1.8 1 0 0 1 1 1 0 Cag pathogenicity island, type IV secretory system SBDS_C PF09377.10 ORY49542.1 - 0.15 12.1 0.2 0.28 11.2 0.2 1.5 1 1 0 1 1 1 0 SBDS protein C-terminal domain Sec63 PF02889.16 ORY49543.1 - 2.4e-29 102.3 0.1 4.8e-29 101.3 0.1 1.5 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 ORY49543.1 - 4.1e-23 82.1 0.0 8.6e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ORY49543.1 - 4.9e-14 52.7 0.0 9.1e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORY49543.1 - 1e-10 41.9 0.0 6e-09 36.2 0.0 3.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 ORY49543.1 - 0.00015 22.1 0.0 0.00041 20.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY49543.1 - 0.00028 21.2 0.0 0.0007 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 ORY49543.1 - 0.00036 20.2 0.0 0.00079 19.0 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain HHH_5 PF14520.6 ORY49543.1 - 0.00039 21.0 0.0 0.00096 19.7 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_30 PF13604.6 ORY49543.1 - 0.00052 19.8 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain FAP PF07174.11 ORY49543.1 - 0.013 15.0 11.2 0.023 14.2 11.2 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DNA_pol_lambd_f PF10391.9 ORY49543.1 - 0.015 15.1 0.0 0.049 13.5 0.0 1.9 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Helicase_RecD PF05127.14 ORY49543.1 - 0.017 15.0 0.0 0.051 13.4 0.0 1.8 1 0 0 1 1 1 0 Helicase T2SSE PF00437.20 ORY49543.1 - 0.033 13.3 0.0 0.18 10.8 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF4332 PF14229.6 ORY49543.1 - 0.052 13.8 0.0 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Cdd1 PF11731.8 ORY49543.1 - 0.099 12.9 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 Pathogenicity locus YL1 PF05764.13 ORY49545.1 - 0.013 15.7 5.9 0.013 15.7 5.9 1.4 2 0 0 2 2 2 0 YL1 nuclear protein Spt5_N PF11942.8 ORY49545.1 - 0.18 12.8 4.3 0.37 11.8 4.3 1.4 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal MMADHC PF10229.9 ORY49546.1 - 4e-21 76.0 0.0 9e-21 74.8 0.0 1.6 1 1 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein Abhydrolase_3 PF07859.13 ORY49547.1 - 2.9e-25 89.4 0.3 4.6e-25 88.7 0.3 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY49547.1 - 1.3e-13 50.6 0.0 3.2e-13 49.3 0.0 1.5 1 1 0 1 1 1 1 Steryl acetyl hydrolase QRPTase_C PF01729.19 ORY49548.1 - 6.8e-56 188.7 0.0 8.4e-56 188.4 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 ORY49548.1 - 1.3e-17 63.6 0.0 4.8e-17 61.8 0.0 1.9 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Nup35_RRM PF05172.13 ORY49549.1 - 8.5e-06 25.7 0.0 5.6e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 ORY49549.1 - 0.0066 16.4 0.0 0.014 15.3 0.0 1.6 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF5427 PF10310.9 ORY49549.1 - 2.4 7.0 14.2 12 4.7 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5427) Macin PF14865.6 ORY49551.1 - 0.011 16.2 0.0 0.026 15.1 0.0 1.6 1 0 0 1 1 1 0 Macin CCDC24 PF15669.5 ORY49551.1 - 0.043 13.7 4.2 0.078 12.8 0.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family RRM_1 PF00076.22 ORY49552.1 - 1e-16 60.5 2.3 0.00057 19.7 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 ORY49552.1 - 0.14 12.2 0.1 8.9 6.5 0.0 3.0 3 0 0 3 3 3 0 Limkain b1 OrfB_Zn_ribbon PF07282.11 ORY49553.1 - 0.006 16.5 0.0 0.006 16.5 0.0 2.4 2 0 0 2 2 2 1 Putative transposase DNA-binding domain Cullin PF00888.22 ORY49554.1 - 1.2e-189 631.9 0.0 1.4e-189 631.7 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 ORY49554.1 - 1.4e-27 95.5 0.1 3.4e-27 94.2 0.1 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain BTB PF00651.31 ORY49555.1 - 0.089 13.0 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 BTB/POZ domain P33MONOX PF15302.6 ORY49555.1 - 0.25 11.0 5.9 2.5 7.7 1.9 2.2 1 1 1 2 2 2 0 P33 mono-oxygenase DUF92 PF01940.16 ORY49556.1 - 3.3e-78 262.4 7.0 3.9e-78 262.1 7.0 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 zf-CCCH_4 PF18044.1 ORY49557.1 - 2.6e-06 27.1 15.6 0.0032 17.2 2.6 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 ORY49557.1 - 9.7e-06 25.4 9.7 0.011 15.6 1.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY49557.1 - 0.00096 19.1 18.8 0.011 15.7 4.5 2.6 2 0 0 2 2 2 2 Zinc finger domain IBV_3C PF03620.13 ORY49557.1 - 0.084 13.4 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 IBV 3C protein Complex1_LYR PF05347.15 ORY49558.1 - 2.5e-08 33.8 0.2 3.4e-08 33.4 0.2 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Pkinase PF00069.25 ORY49559.1 - 1e-42 146.3 0.0 1.7e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY49559.1 - 5.2e-42 143.9 0.0 8.6e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY49559.1 - 4.1e-05 23.0 0.0 6.8e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family C1_1 PF00130.22 ORY49559.1 - 8.1e-05 22.4 1.4 0.00014 21.7 1.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) APH PF01636.23 ORY49559.1 - 0.013 15.4 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY49559.1 - 0.017 13.9 0.0 0.03 13.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase PHD PF00628.29 ORY49559.1 - 0.033 14.1 3.1 0.068 13.1 3.1 1.5 1 0 0 1 1 1 0 PHD-finger Haspin_kinase PF12330.8 ORY49559.1 - 0.041 12.8 0.0 0.07 12.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 ORY49559.1 - 0.054 12.8 0.0 0.12 11.7 0.0 1.5 2 0 0 2 2 2 0 Kinase-like zf-RING_9 PF13901.6 ORY49559.1 - 0.077 13.0 0.7 0.14 12.1 0.7 1.4 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon FTA2 PF13095.6 ORY49559.1 - 0.079 12.6 0.1 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Prok-RING_1 PF14446.6 ORY49559.1 - 0.2 11.6 4.0 0.38 10.7 4.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-HC5HC2H_2 PF13832.6 ORY49559.1 - 0.2 11.8 1.3 0.4 10.9 1.3 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 ORY49559.1 - 0.25 11.6 0.9 0.51 10.6 0.9 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain zinc_ribbon_5 PF13719.6 ORY49559.1 - 0.55 10.0 1.8 1.2 8.9 1.8 1.5 1 0 0 1 1 1 0 zinc-ribbon domain CAP_GLY PF01302.25 ORY49562.1 - 7.5e-22 77.1 0.6 9.7e-22 76.8 0.6 1.1 1 0 0 1 1 1 1 CAP-Gly domain DUF4483 PF14825.6 ORY49563.1 - 1.3e-40 138.8 0.0 4.2e-40 137.1 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4483) GAF PF01590.26 ORY49565.1 - 1.3e-23 84.1 0.0 5.6e-14 52.9 0.0 2.5 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 ORY49565.1 - 2.3e-18 66.8 0.0 6.8e-11 42.6 0.0 2.5 2 0 0 2 2 2 2 GAF domain Guanylate_cyc PF00211.20 ORY49565.1 - 7.1e-16 58.4 0.0 1.5e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain GAF_3 PF13492.6 ORY49565.1 - 3.7e-09 37.0 0.0 2.3e-07 31.2 0.0 2.5 2 0 0 2 2 2 1 GAF domain PseudoU_synth_1 PF01416.20 ORY49567.1 - 3.3e-12 46.8 0.0 1.7e-10 41.3 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase Stig1 PF04885.13 ORY49568.1 - 1.9e-06 28.4 4.8 2e-06 28.3 4.8 1.1 1 0 0 1 1 1 1 Stigma-specific protein, Stig1 Fer4_4 PF12800.7 ORY49568.1 - 4.9 7.9 10.3 1.3 9.7 6.6 2.1 2 1 0 2 2 2 0 4Fe-4S binding domain zf-Tim10_DDP PF02953.15 ORY49569.1 - 2.8e-14 52.5 3.0 4.1e-14 52.0 3.0 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Chitin_synth_2 PF03142.15 ORY49570.1 - 3.8e-240 798.0 0.2 5.4e-240 797.5 0.2 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 ORY49570.1 - 9.6e-118 394.2 0.0 1.3e-117 393.8 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 ORY49570.1 - 3.4e-18 65.3 0.3 3.6e-17 62.0 1.6 2.0 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 ORY49570.1 - 8.5e-15 55.2 2.4 2.7e-14 53.6 2.4 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY49570.1 - 8.6e-10 38.9 0.0 1.4e-08 35.0 0.0 2.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.28 ORY49570.1 - 7.8e-06 25.9 0.7 0.00011 22.3 0.1 2.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.26 ORY49570.1 - 1.8e-05 24.6 0.0 0.0021 17.9 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 ORY49570.1 - 0.003 17.0 0.0 0.053 13.0 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 AAA_22 PF13401.6 ORY49570.1 - 0.0057 16.9 0.2 0.033 14.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 ORY49570.1 - 0.015 14.9 0.1 0.39 10.2 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 ORY49570.1 - 0.085 13.2 1.3 4.5 7.7 0.0 2.8 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.17 ORY49570.1 - 0.16 12.1 0.1 0.36 10.9 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain zf-NF-X1 PF01422.17 ORY49571.1 - 0.0044 17.1 36.1 0.0079 16.2 14.3 13.0 14 1 0 14 14 14 5 NF-X1 type zinc finger INSIG PF07281.12 ORY49572.1 - 1.7e-26 93.2 6.9 9.8e-25 87.4 6.9 2.8 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) Na_Pi_cotrans PF02690.15 ORY49572.1 - 0.012 15.7 1.4 0.76 9.9 0.2 2.3 2 0 0 2 2 2 0 Na+/Pi-cotransporter ThrE PF06738.12 ORY49572.1 - 0.21 10.9 2.9 0.42 9.9 2.9 1.5 1 0 0 1 1 1 0 Putative threonine/serine exporter Tyr_Deacylase PF02580.16 ORY49573.1 - 2.1e-53 180.7 0.0 2.3e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase SPX PF03105.19 ORY49574.1 - 2.7e-14 53.9 7.6 6.8e-07 29.5 0.0 2.1 1 1 1 2 2 2 2 SPX domain Phosphatase PF15698.5 ORY49574.1 - 0.14 11.2 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Phosphatase Nrap_D4 PF17405.2 ORY49574.1 - 0.23 10.8 4.0 2.3 7.5 0.4 2.2 1 1 1 2 2 2 0 Nrap protein nucleotidyltransferase domain 4 GDPD PF03009.17 ORY49575.1 - 1.3e-12 48.1 0.0 1.3e-12 48.0 0.0 1.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family PhoLip_ATPase_C PF16212.5 ORY49576.1 - 2.9e-63 213.9 25.9 2.9e-63 213.9 25.9 2.8 2 1 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 ORY49576.1 - 3.7e-21 74.6 0.3 3.7e-21 74.6 0.3 1.9 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 ORY49576.1 - 9.3e-14 51.3 0.0 6.5e-12 45.4 0.0 2.7 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 ORY49576.1 - 6.3e-10 39.7 0.0 0.00045 20.6 0.0 3.4 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORY49576.1 - 6.7e-05 22.5 0.0 0.00024 20.7 0.0 2.0 1 1 0 1 1 1 1 E1-E2 ATPase HAD PF12710.7 ORY49576.1 - 0.0066 16.9 0.0 4.2 7.7 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORY49576.1 - 0.048 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pyr_redox_2 PF07992.14 ORY49577.1 - 3.3e-65 220.2 5.8 4.6e-65 219.8 5.8 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORY49577.1 - 1.1e-43 148.0 1.1 2e-43 147.1 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ORY49577.1 - 5e-21 75.1 9.6 3.1e-19 69.3 0.6 3.4 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORY49577.1 - 8.1e-10 38.6 0.3 8.1e-10 38.6 0.3 2.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 ORY49577.1 - 1.7e-08 34.0 11.8 9.5e-06 24.9 2.7 3.3 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_3 PF13738.6 ORY49577.1 - 3.1e-08 33.3 6.2 6.1e-06 25.7 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY49577.1 - 2.3e-06 26.9 12.7 2.6e-05 23.5 7.6 3.0 2 1 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 ORY49577.1 - 6.7e-06 26.2 2.6 0.0022 18.2 0.6 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 ORY49577.1 - 4.9e-05 22.6 1.0 0.046 12.9 0.0 2.7 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 ORY49577.1 - 0.0002 20.7 3.7 0.0081 15.4 0.2 2.4 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 ORY49577.1 - 0.0049 15.6 1.6 0.0049 15.6 1.6 3.9 3 1 1 4 4 4 1 HI0933-like protein AlaDh_PNT_C PF01262.21 ORY49577.1 - 0.0079 15.5 10.7 0.13 11.6 0.6 3.1 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 ORY49577.1 - 0.031 13.5 3.7 1.2 8.3 0.8 2.4 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 ORY49577.1 - 1 8.4 2.7 1.3 8.0 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein DAO PF01266.24 ORY49577.1 - 1.6 8.2 12.1 5.6 6.4 0.6 3.3 2 1 1 3 3 3 0 FAD dependent oxidoreductase zf-RING_2 PF13639.6 ORY49578.1 - 7.6e-08 32.6 2.5 1.6e-07 31.5 2.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORY49578.1 - 4.3e-06 26.5 1.8 1.2e-05 25.1 1.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY49578.1 - 3.6e-05 23.9 2.0 0.00011 22.4 2.0 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ORY49578.1 - 0.00016 21.6 5.3 0.00026 21.0 3.7 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 ORY49578.1 - 0.00018 21.2 0.5 0.00034 20.3 0.5 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORY49578.1 - 0.0002 21.1 2.3 0.00049 19.9 2.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 ORY49578.1 - 0.00071 19.3 1.5 0.0015 18.3 1.5 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 ORY49578.1 - 0.0012 18.9 1.4 0.0016 18.4 0.3 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 ORY49578.1 - 0.0012 18.6 1.9 0.0023 17.8 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY49578.1 - 0.004 17.1 2.1 0.0078 16.1 2.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain FANCL_C PF11793.8 ORY49578.1 - 0.0043 17.2 2.0 0.017 15.3 0.9 2.3 2 1 0 2 2 2 1 FANCL C-terminal domain Prok-RING_4 PF14447.6 ORY49578.1 - 0.009 15.9 3.3 0.02 14.8 3.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 ORY49578.1 - 0.014 15.0 1.3 0.014 15.0 1.3 1.9 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 ORY49578.1 - 0.016 15.5 1.5 0.036 14.4 1.5 1.6 1 1 0 1 1 1 0 RING-like domain ARA70 PF12489.8 ORY49578.1 - 0.068 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Nuclear coactivator zf-C3HC4_4 PF15227.6 ORY49578.1 - 0.099 12.8 1.8 0.24 11.6 1.8 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C4_Topoisom PF01396.19 ORY49578.1 - 0.13 12.1 1.7 0.27 11.1 0.3 2.1 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger PHD PF00628.29 ORY49578.1 - 0.39 10.6 2.4 0.84 9.6 2.4 1.6 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 ORY49578.1 - 0.44 10.5 4.0 2.5 8.1 0.3 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3H2C3 PF17122.5 ORY49578.1 - 5 7.2 7.5 1.7 8.8 2.4 2.4 2 0 0 2 2 2 0 Zinc-finger ATP-synt_DE_N PF02823.16 ORY49579.1 - 4.2e-13 49.0 0.0 6.3e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ATP-synt_DE PF00401.20 ORY49579.1 - 0.027 14.7 3.7 0.048 13.9 3.7 1.4 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain ATP-synt_ab PF00006.25 ORY49580.1 - 2.6e-61 207.0 0.0 3.7e-61 206.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 ORY49580.1 - 0.028 13.6 0.8 0.13 11.4 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain ATPase PF06745.13 ORY49580.1 - 0.029 13.7 0.1 0.051 12.9 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA PF00004.29 ORY49580.1 - 0.045 14.2 0.0 0.62 10.5 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 ORY49580.1 - 0.047 14.0 1.2 0.29 11.5 0.2 2.3 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 ORY49580.1 - 0.073 13.0 0.2 0.15 11.9 0.1 1.5 2 0 0 2 2 2 0 RsgA GTPase DUF463 PF04317.12 ORY49580.1 - 0.083 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 NACHT PF05729.12 ORY49580.1 - 0.11 12.4 0.0 0.31 10.9 0.0 1.7 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 ORY49580.1 - 0.16 12.4 0.0 0.39 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase HNF-1A_C PF04813.12 ORY49580.1 - 0.18 12.6 0.0 0.36 11.6 0.0 1.5 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus PPR_3 PF13812.6 ORY49581.1 - 1.4e-06 28.3 0.0 1.7 8.8 0.0 3.8 3 0 0 3 3 3 3 Pentatricopeptide repeat domain PPR_2 PF13041.6 ORY49581.1 - 0.0058 16.8 0.0 4.2 7.7 0.0 3.6 4 0 0 4 4 4 2 PPR repeat family DUF2059 PF09832.9 ORY49581.1 - 0.024 14.7 0.7 0.15 12.1 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2059) Alk_phosphatase PF00245.20 ORY49581.1 - 0.25 10.3 14.5 1.5 7.7 10.2 2.4 2 0 0 2 2 2 0 Alkaline phosphatase Band_7 PF01145.25 ORY49582.1 - 1.7e-21 77.0 3.1 2.5e-21 76.5 3.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family DEAD PF00270.29 ORY49583.1 - 2.6e-45 154.3 0.0 4.7e-45 153.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY49583.1 - 8.2e-25 87.3 0.1 2.1e-23 82.8 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 ORY49583.1 - 4.7e-20 71.6 0.1 3.7e-19 68.7 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4217) ResIII PF04851.15 ORY49583.1 - 4.9e-06 26.6 0.0 4.7e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RRM_1 PF00076.22 ORY49584.1 - 6e-27 93.3 0.0 1.4e-12 47.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Androgen_recep PF02166.16 ORY49584.1 - 5.3 5.8 16.2 10 4.8 0.3 2.1 2 0 0 2 2 2 0 Androgen receptor RRM_1 PF00076.22 ORY49586.1 - 1.3e-24 85.8 0.0 3.3e-12 46.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC48_2 PF02933.17 ORY49586.1 - 0.098 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 Cation_efflux PF01545.21 ORY49589.1 - 1.5e-22 80.3 7.3 2e-22 79.9 7.3 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORY49589.1 - 8.5e-11 41.8 0.2 2.7e-10 40.2 0.2 1.8 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter FYVE PF01363.21 ORY49590.1 - 7.2e-15 54.9 9.4 1.3e-14 54.1 9.4 1.4 1 0 0 1 1 1 1 FYVE zinc finger GAS PF13851.6 ORY49590.1 - 3.1e-05 23.4 37.2 5.3e-05 22.7 16.3 3.5 2 1 0 3 3 3 2 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 ORY49590.1 - 0.005 16.7 14.4 0.005 16.7 14.4 4.0 1 1 2 3 3 3 1 Coiled-coil region of CCDC155 or KASH CENP-F_leu_zip PF10473.9 ORY49590.1 - 0.0097 15.9 39.3 0.019 15.0 3.4 4.8 2 1 2 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF465 PF04325.13 ORY49590.1 - 0.028 14.5 0.6 0.028 14.5 0.6 4.5 5 0 0 5 5 4 0 Protein of unknown function (DUF465) MscS_porin PF12795.7 ORY49590.1 - 0.04 13.5 49.2 0.74 9.3 0.5 3.2 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain Filament PF00038.21 ORY49590.1 - 0.093 12.3 32.9 0.016 14.8 12.2 3.3 1 1 2 3 3 3 0 Intermediate filament protein TMF_TATA_bd PF12325.8 ORY49590.1 - 0.15 12.3 32.5 1 9.6 5.6 5.0 3 1 2 5 5 5 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 ORY49590.1 - 0.15 11.4 42.2 0.42 9.9 19.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Myosin_tail_1 PF01576.19 ORY49590.1 - 0.22 9.3 39.2 0.28 8.9 30.7 2.0 2 0 0 2 2 2 0 Myosin tail APG6_N PF17675.1 ORY49590.1 - 0.3 11.6 50.2 2.8 8.5 13.7 4.7 2 1 2 4 4 4 0 Apg6 coiled-coil region Surfac_D-trimer PF09006.11 ORY49590.1 - 0.51 10.3 2.0 3.6 7.5 0.0 3.0 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation DUF3322 PF11795.8 ORY49590.1 - 0.62 10.0 14.4 0.094 12.7 7.0 2.5 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Fez1 PF06818.15 ORY49590.1 - 0.63 10.5 33.6 19 5.6 4.1 4.0 1 1 2 3 3 2 0 Fez1 DUF2935 PF11155.8 ORY49590.1 - 1.6 9.0 5.2 49 4.3 5.2 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) BLOC1_2 PF10046.9 ORY49590.1 - 2.5 8.5 30.3 1.6 9.1 6.0 4.8 3 2 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3502 PF12010.8 ORY49590.1 - 2.8 8.6 4.6 2 9.0 0.1 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF3502) Lectin_N PF03954.14 ORY49590.1 - 3 7.6 24.2 0.69 9.7 1.1 5.0 3 1 2 5 5 5 0 Hepatic lectin, N-terminal domain AAA_13 PF13166.6 ORY49590.1 - 3.1 6.3 36.4 0.021 13.5 16.5 2.9 1 1 2 3 3 3 0 AAA domain Swi5 PF07061.11 ORY49590.1 - 3.9 7.6 28.6 0.93 9.6 1.6 5.8 3 2 1 4 4 3 0 Swi5 Fib_alpha PF08702.10 ORY49590.1 - 4.7 7.4 19.7 10 6.3 0.1 4.9 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family TFIIA PF03153.13 ORY49591.1 - 0.001 19.1 10.5 0.001 19.1 10.5 3.4 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 ORY49591.1 - 0.0077 16.3 15.8 0.4 10.8 3.6 2.7 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 RNB PF00773.19 ORY49593.1 - 3.2e-60 204.2 0.0 7.8e-60 202.9 0.0 1.6 1 1 0 1 1 1 1 RNB domain zf-RanBP PF00641.18 ORY49594.1 - 7e-26 89.2 32.4 8.9e-08 31.3 1.5 4.4 4 0 0 4 4 4 4 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 ORY49594.1 - 2.4e-05 24.1 0.0 8.5e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 ORY49594.1 - 0.011 15.4 0.9 0.028 14.1 0.0 2.1 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated RNase_T PF00929.24 ORY49594.1 - 0.027 15.0 0.0 0.093 13.3 0.0 1.8 1 1 0 1 1 1 0 Exonuclease Prim_Zn_Ribbon PF08273.12 ORY49594.1 - 0.81 10.0 0.1 0.81 10.0 0.1 5.2 5 1 0 5 5 5 0 Zinc-binding domain of primase-helicase Cytochrome_C7 PF14522.6 ORY49594.1 - 5 7.2 11.6 0.96 9.5 0.4 3.0 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c DFRP_C PF16543.5 ORY49595.1 - 3.8e-23 81.8 5.2 3.8e-23 81.8 5.2 3.3 3 0 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 ORY49595.1 - 3.3e-07 30.1 2.1 3.3e-07 30.1 2.1 3.0 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY49595.1 - 3e-06 27.1 7.3 3e-06 27.1 7.3 3.3 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_4 PF18044.1 ORY49595.1 - 8.5e-05 22.2 1.4 8.5e-05 22.2 1.4 3.2 3 0 0 3 3 3 1 CCCH-type zinc finger Torus PF16131.5 ORY49595.1 - 0.001 19.8 18.7 0.011 16.5 7.3 4.0 2 1 1 3 3 3 2 Torus domain zf-CCCH_3 PF15663.5 ORY49595.1 - 0.0023 18.1 0.3 0.0023 18.1 0.3 3.3 2 1 2 4 4 4 1 Zinc-finger containing family DUF4385 PF14328.6 ORY49595.1 - 0.021 14.9 1.3 0.021 14.9 1.3 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4385) DUF1933 PF09147.10 ORY49595.1 - 0.028 14.0 0.1 0.83 9.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1933) zf-CCCH_2 PF14608.6 ORY49595.1 - 1.4 9.5 14.9 0.22 12.0 5.2 3.0 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DUF563 PF04577.14 ORY49596.1 - 1.2e-19 71.3 0.0 2.2e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) LRR_8 PF13855.6 ORY49597.1 - 8e-09 35.1 2.7 6.4e-06 25.8 0.6 2.7 2 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 ORY49597.1 - 5.3e-07 29.9 3.9 5e-05 23.6 0.9 3.0 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY49597.1 - 0.0019 18.5 2.1 1.9 9.3 0.8 4.6 3 0 0 3 3 3 1 Leucine Rich Repeat Ribosomal_S11 PF00411.19 ORY49599.1 - 3.2e-24 85.4 1.6 3.7e-24 85.2 0.2 1.7 2 0 0 2 2 2 1 Ribosomal protein S11 EF-hand_7 PF13499.6 ORY49600.1 - 3.1e-29 101.2 0.6 1.7e-13 50.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORY49600.1 - 7.7e-25 84.6 4.3 2.5e-07 29.8 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 ORY49600.1 - 4.2e-21 73.0 3.5 9.2e-07 28.3 0.0 4.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 ORY49600.1 - 1.9e-14 53.2 4.8 5.1e-06 26.2 0.0 3.5 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 ORY49600.1 - 1.6e-11 44.3 0.1 5.1e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 ORY49600.1 - 6.3e-11 41.3 2.7 0.07 12.7 0.8 4.9 4 1 0 4 4 4 3 EF hand EF-hand_11 PF08976.11 ORY49600.1 - 2.8e-06 28.1 0.0 0.0046 17.8 0.0 2.0 1 1 1 2 2 2 2 EF-hand domain GPHH PF16905.5 ORY49600.1 - 2e-05 24.3 0.0 0.32 10.8 0.0 3.1 3 0 0 3 3 3 2 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_4 PF12763.7 ORY49600.1 - 0.00016 21.6 0.4 0.015 15.3 0.2 2.0 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 ORY49600.1 - 0.0033 17.4 0.2 0.022 14.7 0.0 2.0 2 0 0 2 2 2 1 Tellurite resistance protein TerB Caleosin PF05042.13 ORY49600.1 - 0.02 14.8 0.2 0.94 9.4 0.0 2.6 1 1 1 2 2 2 0 Caleosin related protein DUF3349 PF11829.8 ORY49600.1 - 0.029 15.1 0.2 5.3 7.9 0.1 2.7 1 1 3 4 4 4 0 Protein of unknown function (DUF3349) UPF0154 PF03672.13 ORY49600.1 - 0.033 14.2 0.0 14 5.8 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) EF-hand_14 PF17959.1 ORY49600.1 - 0.041 14.2 0.2 9.2 6.7 0.1 2.4 2 1 0 2 2 2 0 EF-hand domain SPARC_Ca_bdg PF10591.9 ORY49600.1 - 0.048 14.0 0.0 0.95 9.8 0.0 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2713 PF10897.8 ORY49600.1 - 0.073 12.7 0.1 0.086 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) Spore_III_AB PF09548.10 ORY49600.1 - 0.11 12.5 0.1 0.35 11.0 0.0 1.7 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Dockerin_1 PF00404.18 ORY49600.1 - 0.26 11.5 3.8 4 7.7 3.8 2.4 1 1 0 1 1 1 0 Dockerin type I domain PDCD2_C PF04194.13 ORY49601.1 - 1.7e-37 129.2 5.2 2.9e-33 115.4 0.0 3.4 3 0 0 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain SPT6_acidic PF14632.6 ORY49601.1 - 0.095 13.3 5.9 0.23 12.1 5.9 1.6 1 0 0 1 1 1 0 Acidic N-terminal SPT6 PhnA_Zn_Ribbon PF08274.12 ORY49601.1 - 0.18 11.8 2.4 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 PhnA Zinc-Ribbon L27_1 PF09058.10 ORY49601.1 - 0.26 11.3 1.3 2.3 8.3 0.4 2.6 3 0 0 3 3 3 0 L27_1 Ndc1_Nup PF09531.10 ORY49601.1 - 1.2 7.8 4.8 1.4 7.5 4.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Vps8 PF12816.7 ORY49602.1 - 1e-56 191.6 0.2 4.1e-56 189.6 0.1 2.1 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 ORY49602.1 - 5.3e-09 36.1 0.7 0.041 13.8 0.0 4.2 4 0 0 4 4 4 2 Region in Clathrin and VPS zf-RING_5 PF14634.6 ORY49602.1 - 0.00015 21.6 2.1 0.00029 20.7 2.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 ORY49602.1 - 0.0012 19.1 0.7 0.0031 17.8 0.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORY49602.1 - 0.0013 18.5 0.1 0.004 17.0 0.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 ORY49602.1 - 0.067 13.2 0.6 0.16 12.0 0.6 1.6 1 0 0 1 1 1 0 Zinc-finger zf-RING_UBOX PF13445.6 ORY49602.1 - 0.068 13.2 0.5 0.23 11.5 0.5 1.9 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.29 ORY49602.1 - 0.092 12.7 3.1 0.29 11.1 3.1 1.9 1 1 0 1 1 1 0 PHD-finger zf-RING_11 PF17123.5 ORY49602.1 - 0.096 12.5 3.6 0.064 13.0 0.4 2.3 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_2 PF13639.6 ORY49602.1 - 0.11 12.9 3.1 0.34 11.3 3.1 2.0 1 0 0 1 1 1 0 Ring finger domain Zn_ribbon_17 PF17120.5 ORY49602.1 - 0.16 11.7 0.3 0.71 9.5 0.1 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type ANAPC4_WD40 PF12894.7 ORY49602.1 - 0.18 12.1 0.3 1.4 9.3 0.0 2.5 3 0 0 3 3 2 0 Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4 PF00097.25 ORY49602.1 - 0.87 9.5 2.4 1.8 8.5 2.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Katanin_con80 PF13925.6 ORY49603.1 - 2.3e-38 131.8 0.6 3.7e-38 131.1 0.6 1.3 1 0 0 1 1 1 1 con80 domain of Katanin WD40 PF00400.32 ORY49603.1 - 1.3e-16 60.7 10.6 0.0007 20.4 0.3 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY49603.1 - 1.3e-13 51.1 0.1 2.6e-05 24.4 0.1 4.7 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY49603.1 - 0.00066 19.6 0.0 0.61 9.9 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 ORY49603.1 - 0.028 12.7 0.0 1.8 6.8 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz Actin PF00022.19 ORY49604.1 - 8.5e-133 442.9 0.0 2.9e-132 441.1 0.0 1.7 1 1 0 1 1 1 1 Actin GerD PF17898.1 ORY49604.1 - 0.14 12.2 0.6 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 Spore germination GerD central core domain UQ_con PF00179.26 ORY49605.1 - 1.3e-49 167.5 0.0 1.5e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY49605.1 - 0.0013 19.0 0.2 0.0021 18.3 0.1 1.5 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 ORY49605.1 - 0.0034 17.1 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 ORY49605.1 - 0.092 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain Mg_trans_NIPA PF05653.14 ORY49606.1 - 2.1e-23 82.9 13.3 2.5e-14 53.1 1.9 2.5 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 ORY49606.1 - 8.5e-06 26.0 3.6 8.5e-06 26.0 3.6 3.7 3 1 0 3 3 3 1 EamA-like transporter family TMEM234 PF10639.9 ORY49606.1 - 0.0035 17.3 0.2 0.012 15.6 0.2 1.9 1 0 0 1 1 1 1 Putative transmembrane family 234 Securin PF04856.13 ORY49608.1 - 0.0019 18.2 9.9 0.0034 17.4 9.9 1.4 1 0 0 1 1 1 1 Securin sister-chromatid separation inhibitor TFIIA PF03153.13 ORY49608.1 - 0.073 13.1 22.2 0.09 12.8 22.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 ORY49608.1 - 1.7 7.2 12.6 1.9 7.1 12.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Suf PF05843.14 ORY49608.1 - 2.5 8.0 12.0 3.4 7.6 12.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 ORY49608.1 - 5 5.8 6.8 6.5 5.4 6.8 1.2 1 0 0 1 1 1 0 Presenilin NUFIP1 PF10453.9 ORY49609.1 - 1e-13 50.9 1.0 3.3e-13 49.2 1.0 1.8 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH_4 PF18044.1 ORY49609.1 - 2.1e-07 30.6 3.2 4.3e-07 29.6 3.2 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ORY49609.1 - 1.7e-06 27.9 4.8 3.1e-06 27.1 4.8 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 ORY49609.1 - 3.2e-05 23.7 1.3 6.8e-05 22.7 1.3 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 ORY49609.1 - 0.00043 21.0 4.0 0.0024 18.6 4.0 2.3 1 1 1 2 2 2 1 Torus domain zf-CCCH_3 PF15663.5 ORY49609.1 - 0.012 15.8 0.1 0.05 13.8 0.1 2.0 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 ORY49609.1 - 0.012 16.0 4.6 0.012 16.0 4.6 1.8 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-C2H2_4 PF13894.6 ORY49609.1 - 0.035 14.9 0.8 0.035 14.9 0.8 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger YABBY PF04690.13 ORY49609.1 - 2.8 8.5 13.7 0.95 10.0 7.0 2.9 2 1 0 2 2 2 0 YABBY protein B9-C2 PF07162.11 ORY49610.1 - 9.2e-46 156.1 0.0 1.1e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein ASH PF15780.5 ORY49611.1 - 3e-13 49.8 1.6 0.14 12.3 0.1 10.4 10 2 2 12 12 12 3 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 ORY49611.1 - 2e-12 47.0 0.1 0.0092 16.0 0.0 7.1 6 0 0 6 6 6 3 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 ORY49611.1 - 9.3e-05 22.6 8.4 0.26 11.6 0.0 7.6 6 1 2 8 8 8 1 Transmembrane protein 131-like Motile_Sperm PF00635.26 ORY49611.1 - 0.0012 18.7 3.4 0.55 10.1 0.0 6.1 7 0 0 7 7 7 1 MSP (Major sperm protein) domain FixG_C PF11614.8 ORY49611.1 - 0.0013 18.9 0.0 8.4 6.6 0.0 5.1 4 0 0 4 4 4 1 IG-like fold at C-terminal of FixG, putative oxidoreductase PapD-like PF14874.6 ORY49611.1 - 0.031 14.4 0.4 14 5.9 0.0 4.8 6 0 0 6 6 6 0 Flagellar-associated PapD-like DUF3915 PF13054.6 ORY49611.1 - 0.057 13.4 5.0 0.036 14.0 2.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) DUF1090 PF06476.12 ORY49611.1 - 1.7 8.8 5.1 4.4 7.5 5.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) Apis_Csd PF11671.8 ORY49611.1 - 1.8 8.5 10.2 12 5.9 0.1 2.6 2 0 0 2 2 2 0 Complementary sex determiner protein DUF5321 PF17254.2 ORY49613.1 - 0.013 14.9 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5321) DUF2004 PF09406.10 ORY49613.1 - 0.092 13.1 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2004) Phi_1 PF04674.12 ORY49615.1 - 0.028 13.7 0.7 0.22 10.8 0.0 2.5 3 1 1 4 4 4 0 Phosphate-induced protein 1 conserved region Herpes_U47 PF05467.11 ORY49615.1 - 0.058 11.5 0.0 0.086 11.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 RRM_1 PF00076.22 ORY49616.1 - 6.6e-14 51.5 0.0 2.8e-06 27.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 ORY49616.1 - 4.6e-05 22.6 2.5 4.6e-05 22.6 2.5 1.8 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others TauD PF02668.16 ORY49617.1 - 5.7e-45 154.2 0.1 6.4e-45 154.0 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 ORY49617.1 - 0.021 13.9 0.0 0.027 13.6 0.0 1.4 1 1 0 1 1 1 0 CsiD PMT PF02366.18 ORY49618.1 - 2.1e-80 269.9 22.2 2.1e-80 269.9 22.2 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORY49618.1 - 4.8e-58 196.1 10.1 4.8e-58 196.1 10.1 2.6 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORY49618.1 - 1.3e-29 103.4 0.2 2.1e-29 102.7 0.2 1.2 1 0 0 1 1 1 1 MIR domain Anophelin PF10731.9 ORY49618.1 - 0.31 10.9 0.9 0.78 9.6 0.9 1.6 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito FAM176 PF14851.6 ORY49619.1 - 0.041 13.5 1.7 0.043 13.5 1.7 1.1 1 0 0 1 1 1 0 FAM176 family DUF913 PF06025.12 ORY49619.1 - 0.14 11.1 0.2 0.15 11.0 0.2 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DKCLD PF08068.12 ORY49620.1 - 7.6e-35 118.8 0.4 3.2e-33 113.6 0.4 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 ORY49620.1 - 1.2e-25 90.7 0.5 9e-23 81.3 0.5 3.2 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 ORY49620.1 - 7.6e-21 73.9 1.6 1.3e-20 73.1 1.6 1.4 1 0 0 1 1 1 1 PUA domain TruB_C_2 PF16198.5 ORY49620.1 - 4.2e-20 71.7 0.1 9.2e-20 70.6 0.1 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain UPF0113 PF03657.13 ORY49620.1 - 0.0076 16.5 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 UPF0113 PUA domain Ku PF02735.16 ORY49621.1 - 4.9e-43 147.2 0.0 1e-42 146.2 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 ORY49621.1 - 8.3e-34 117.2 0.1 1.3e-33 116.6 0.1 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 ORY49621.1 - 5.4e-14 52.6 0.6 5.4e-14 52.6 0.6 2.3 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm Nup54 PF13874.6 ORY49622.1 - 2.1e-44 151.0 0.9 2.1e-44 151.0 0.9 3.5 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 ORY49622.1 - 5.2e-16 59.3 116.1 8.8e-09 36.1 39.1 3.2 1 1 2 3 3 3 3 Nucleoporin FG repeat region DUF349 PF03993.12 ORY49622.1 - 0.24 11.7 0.2 0.24 11.7 0.2 3.2 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) Peptidase_S64 PF08192.11 ORY49622.1 - 2.6 6.4 16.3 4.7 5.6 16.3 1.3 1 0 0 1 1 1 0 Peptidase family S64 DnaJ_CXXCXGXG PF00684.19 ORY49623.1 - 0.04 14.3 0.2 0.086 13.2 0.2 1.5 1 0 0 1 1 1 0 DnaJ central domain Hypoth_Ymh PF09509.10 ORY49624.1 - 0.00087 19.2 0.7 0.099 12.5 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (Hypoth_ymh) MqsR_toxin PF15723.5 ORY49625.1 - 0.1 13.0 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Motility quorum-sensing regulator, toxin of MqsA CwfJ_C_1 PF04677.15 ORY49626.1 - 1.6e-21 76.4 0.0 3.1e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 zf-CCHC_2 PF13696.6 ORY49626.1 - 9.3e-19 66.9 14.0 3.2e-09 36.4 1.8 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC PF00098.23 ORY49626.1 - 1.1e-07 31.6 8.0 0.00013 21.8 1.1 2.8 2 0 0 2 2 2 2 Zinc knuckle CwfJ_C_2 PF04676.14 ORY49626.1 - 1.6e-06 28.9 0.0 3e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 HIT PF01230.23 ORY49626.1 - 0.03 15.1 0.2 0.078 13.7 0.2 1.7 1 1 0 1 1 1 0 HIT domain zf-CCHC_3 PF13917.6 ORY49626.1 - 0.52 10.3 3.4 2.5 8.2 0.2 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_5 PF14787.6 ORY49626.1 - 2 8.2 9.3 6.7 6.5 2.8 2.6 1 1 1 2 2 2 0 GAG-polyprotein viral zinc-finger zinc-ribbons_6 PF07191.12 ORY49626.1 - 3 7.9 6.1 6.8 6.8 1.9 2.2 1 1 1 2 2 2 0 zinc-ribbons zf-C2H2_10 PF16588.5 ORY49626.1 - 4.3 7.2 7.7 4.6 7.1 1.2 2.5 2 0 0 2 2 2 0 C2H2 zinc-finger DEAD PF00270.29 ORY49628.1 - 7.3e-44 149.6 0.0 1.2e-43 148.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY49628.1 - 9.2e-25 87.2 0.0 6.6e-24 84.4 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 ORY49628.1 - 2e-19 69.5 0.8 3.7e-19 68.7 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 ORY49628.1 - 9.1e-05 22.5 0.1 0.00018 21.5 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ORY49628.1 - 0.0022 17.2 0.0 0.0037 16.5 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF1806 PF08830.10 ORY49628.1 - 0.031 14.2 0.2 0.22 11.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1806) DEAD PF00270.29 ORY49629.1 - 5.3e-27 94.7 0.0 8.9e-27 94.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY49629.1 - 2.8e-24 85.6 0.1 1.1e-23 83.7 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 ORY49629.1 - 3e-19 69.0 0.8 5.8e-19 68.1 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Steroid_dh PF02544.16 ORY49629.1 - 2.5e-13 50.3 0.1 1.7e-12 47.5 0.1 2.4 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 ORY49629.1 - 3.3e-05 23.5 0.0 0.00034 20.2 0.0 2.4 2 1 0 3 3 3 1 Protein of unknown function (DUF1295) DUF1806 PF08830.10 ORY49629.1 - 0.056 13.3 0.2 0.34 10.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1806) PEMT PF04191.13 ORY49629.1 - 0.21 12.0 0.0 0.21 12.0 0.0 2.4 3 0 0 3 3 3 0 Phospholipid methyltransferase FBA PF04300.13 ORY49630.1 - 1.1e-07 31.7 3.6 4.7e-07 29.7 3.6 2.2 1 1 0 1 1 1 1 F-box associated region BUD22 PF09073.10 ORY49630.1 - 0.01 15.2 13.2 0.013 14.9 13.2 1.1 1 0 0 1 1 1 0 BUD22 eIF-3c_N PF05470.12 ORY49630.1 - 0.047 12.0 3.4 0.044 12.1 3.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus RRN3 PF05327.11 ORY49630.1 - 0.28 9.7 3.8 0.3 9.6 3.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CNDH2_C PF16858.5 ORY49630.1 - 0.54 10.1 11.0 0.76 9.6 11.0 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term FYDLN_acid PF09538.10 ORY49630.1 - 0.65 10.7 18.9 1.3 9.7 18.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Pox_Ag35 PF03286.14 ORY49630.1 - 0.83 9.4 12.6 1.3 8.8 12.6 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Zip PF02535.22 ORY49630.1 - 0.93 8.6 2.8 1 8.5 2.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BSP_II PF05432.11 ORY49630.1 - 1.1 8.9 16.5 1.7 8.3 16.5 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Spem1 PF15670.5 ORY49630.1 - 2 7.9 4.4 3.6 7.1 4.4 1.5 1 0 0 1 1 1 0 Spermatid maturation protein 1 Sporozoite_P67 PF05642.11 ORY49630.1 - 2.6 6.0 7.4 3.3 5.7 7.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 ORY49630.1 - 3.5 5.7 20.5 4.3 5.4 20.5 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 ORY49630.1 - 7 6.3 20.4 9.6 5.9 20.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CDC27 PF09507.10 ORY49630.1 - 8.2 5.7 16.8 11 5.3 16.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TRAP_alpha PF03896.16 ORY49630.1 - 8.7 5.5 12.9 18 4.4 12.9 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Steroid_dh PF02544.16 ORY49631.1 - 4.3e-15 56.0 0.1 6e-14 52.3 0.1 2.5 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 ORY49631.1 - 4.6e-06 26.3 0.0 0.0001 21.9 0.0 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.13 ORY49631.1 - 0.056 13.9 0.2 0.056 13.9 0.2 2.8 3 1 0 3 3 3 0 Phospholipid methyltransferase tRNA-synt_2 PF00152.20 ORY49632.1 - 2.6e-100 335.6 0.0 3.1e-100 335.3 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORY49632.1 - 9.5e-11 41.5 0.0 1.8e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 ORY49632.1 - 0.0085 15.6 0.1 0.033 13.7 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.25 ORY49632.1 - 0.013 15.5 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) DEAD PF00270.29 ORY49633.1 - 7.3e-44 149.6 0.0 1.2e-43 148.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY49633.1 - 9.2e-25 87.2 0.0 6.6e-24 84.4 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 ORY49633.1 - 2e-19 69.5 0.8 3.7e-19 68.7 0.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 ORY49633.1 - 9.1e-05 22.5 0.1 0.00018 21.5 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 ORY49633.1 - 0.0022 17.2 0.0 0.0037 16.5 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF1806 PF08830.10 ORY49633.1 - 0.03 14.2 0.2 0.22 11.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1806) FUSC PF04632.12 ORY49634.1 - 0.18 10.3 2.1 0.25 9.8 2.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family EAP30 PF04157.16 ORY49634.1 - 3.6 6.8 7.5 7.3 5.8 7.5 1.4 1 0 0 1 1 1 0 EAP30/Vps36 family T2SSM PF04612.12 ORY49634.1 - 7.5 6.6 14.8 0.65 10.0 8.9 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M BUD22 PF09073.10 ORY49635.1 - 3.8 6.7 9.4 4.6 6.5 9.4 1.1 1 0 0 1 1 1 0 BUD22 Neural_ProG_Cyt PF06567.11 ORY49744.1 - 0.0001 22.5 0.2 1.2 9.3 0.0 2.9 1 1 2 3 3 3 2 Neural chondroitin sulphate proteoglycan cytoplasmic domain MRP-S24 PF14955.6 ORY49744.1 - 0.0009 19.2 0.0 8 6.4 0.0 3.0 1 1 2 3 3 3 2 Mitochondrial ribosome subunit S24 ARTD15_N PF18084.1 ORY49744.1 - 0.0023 18.1 0.2 2.5 8.4 0.0 2.5 1 1 1 2 2 2 2 ARTD15 N-terminal domain PAP2_3 PF14378.6 ORY49744.1 - 0.028 14.1 0.3 6.4 6.4 0.1 2.1 1 1 1 2 2 2 0 PAP2 superfamily Peptidase_C53 PF05550.11 ORY49744.1 - 0.044 13.5 0.1 56 3.4 0.0 3.0 3 0 0 3 3 3 0 Pestivirus Npro endopeptidase C53 Lantibiotic_a PF14867.6 ORY49744.1 - 0.05 13.4 0.0 73 3.2 0.0 3.2 3 0 0 3 3 3 0 Lantibiotic alpha DUF1798 PF08807.10 ORY49744.1 - 0.064 13.4 0.0 26 5.0 0.0 2.8 1 1 2 3 3 3 0 Bacterial domain of unknown function (DUF1798) Bravo_FIGEY PF13882.6 ORY49744.1 - 0.13 13.7 0.1 11 7.5 0.0 2.3 1 1 1 2 2 2 0 Bravo-like intracellular region DUF5315 PF17242.2 ORY49744.1 - 1.6 8.6 7.6 63 3.5 0.1 4.3 1 1 4 5 5 5 0 Disordered region of unknown function (DUF5315) DUF3450 PF11932.8 ORY49746.1 - 0.00036 19.9 1.5 0.00044 19.6 1.2 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) Nsp1_C PF05064.13 ORY49746.1 - 0.001 18.8 1.2 0.0011 18.7 1.2 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region ZapB PF06005.12 ORY49746.1 - 0.0018 18.7 5.1 0.0025 18.2 5.1 1.3 1 1 0 1 1 1 1 Cell division protein ZapB BLOC1_2 PF10046.9 ORY49746.1 - 0.0021 18.3 1.1 0.0027 17.9 1.1 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 ORY49746.1 - 0.0031 17.4 0.9 0.0035 17.2 0.9 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 BST2 PF16716.5 ORY49746.1 - 0.0038 17.8 2.3 0.0049 17.4 2.3 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 GAS PF13851.6 ORY49746.1 - 0.0039 16.6 2.9 0.0044 16.4 2.9 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 ORY49746.1 - 0.017 15.1 2.0 0.017 15.1 2.0 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Cluap1 PF10234.9 ORY49746.1 - 0.018 14.4 1.5 0.019 14.4 1.5 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Tropomyosin_1 PF12718.7 ORY49746.1 - 0.024 14.8 2.5 0.036 14.2 2.5 1.4 1 1 0 1 1 1 0 Tropomyosin like YabA PF06156.13 ORY49746.1 - 0.026 15.1 1.3 0.031 14.9 1.3 1.2 1 0 0 1 1 1 0 Initiation control protein YabA HlyD_D23 PF16576.5 ORY49746.1 - 0.028 13.6 1.0 0.03 13.5 1.0 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Herpes_UL6 PF01763.16 ORY49746.1 - 0.028 12.9 1.7 0.029 12.9 1.7 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like BSP PF04450.12 ORY49746.1 - 0.034 14.0 0.0 0.053 13.3 0.0 1.3 1 1 0 1 1 1 0 Peptidase of plants and bacteria Rab_bind PF16704.5 ORY49746.1 - 0.035 14.1 0.3 2.8 8.1 0.1 2.3 1 1 1 2 2 2 0 Rab binding domain DUF948 PF06103.11 ORY49746.1 - 0.041 14.1 0.5 0.058 13.7 0.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 ORY49746.1 - 0.042 14.4 2.8 0.057 14.0 2.8 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region SlyX PF04102.12 ORY49746.1 - 0.12 13.0 4.7 0.33 11.6 4.7 1.8 1 1 0 1 1 1 0 SlyX Cep57_MT_bd PF06657.13 ORY49746.1 - 0.13 12.7 3.5 1.7 9.2 0.8 2.2 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 XhlA PF10779.9 ORY49746.1 - 0.14 12.3 2.3 0.29 11.4 2.3 1.5 1 0 0 1 1 1 0 Haemolysin XhlA Fib_alpha PF08702.10 ORY49746.1 - 0.15 12.2 3.3 0.49 10.6 3.2 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 ORY49746.1 - 0.25 11.8 2.6 1.1 9.8 2.9 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DivIC PF04977.15 ORY49746.1 - 0.62 9.9 5.3 6.3 6.7 0.4 2.0 1 1 1 2 2 2 0 Septum formation initiator Exc PF07825.11 ORY49747.1 - 0.019 14.9 0.6 0.33 11.0 0.1 2.4 2 0 0 2 2 2 0 Excisionase-like protein HTH_Tnp_Tc3_2 PF01498.18 ORY49747.1 - 0.049 13.9 0.8 0.1 12.8 0.0 2.1 2 0 0 2 2 2 0 Transposase HTH_Tnp_Tc5 PF03221.16 ORY49747.1 - 0.13 12.3 0.2 0.82 9.8 0.0 2.5 3 0 0 3 3 3 0 Tc5 transposase DNA-binding domain DNA_pol_B_thumb PF14791.6 ORY49750.1 - 2.8e-07 30.6 0.0 6.6e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb G-alpha PF00503.20 ORY49751.1 - 4.2e-105 351.8 0.9 5.3e-105 351.5 0.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY49751.1 - 1.9e-16 60.0 1.1 2.2e-12 46.8 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 ORY49751.1 - 1.5e-05 25.2 0.4 0.033 14.4 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 ORY49751.1 - 2e-05 24.1 0.5 0.0063 15.9 0.1 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORY49751.1 - 0.076 12.5 0.4 0.4 10.2 0.1 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Ras PF00071.22 ORY49751.1 - 0.12 11.9 0.3 7.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Ras family G-alpha PF00503.20 ORY49752.1 - 7.2e-107 357.6 0.0 8.4e-107 357.4 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY49752.1 - 3.1e-18 65.8 0.6 6.4e-15 55.0 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 ORY49752.1 - 2.8e-07 30.8 0.4 0.00043 20.5 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 ORY49752.1 - 0.00019 20.9 0.2 0.0077 15.6 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Ras PF00071.22 ORY49752.1 - 0.0064 16.1 0.7 0.71 9.4 0.1 2.3 2 0 0 2 2 2 2 Ras family GTP_EFTU PF00009.27 ORY49752.1 - 0.023 14.3 0.6 0.12 11.9 0.1 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 ORY49752.1 - 0.084 12.2 0.1 0.77 9.1 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.6 ORY49752.1 - 0.12 12.1 0.1 0.49 10.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Anoctamin PF04547.12 ORY49753.1 - 5.5e-99 332.0 20.0 7.6e-99 331.6 20.0 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 ORY49753.1 - 2.8e-23 82.9 6.7 5.5e-15 55.7 0.0 2.3 1 1 0 2 2 2 2 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Ntox15 PF15604.6 ORY49753.1 - 0.0059 16.7 1.2 0.012 15.8 1.2 1.4 1 0 0 1 1 1 1 Novel toxin 15 DUF2663 PF10864.8 ORY49753.1 - 1 9.8 10.0 7.3 7.0 2.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) Cu-oxidase_3 PF07732.15 ORY49754.1 - 6.6e-39 132.6 13.4 2.3e-37 127.6 0.9 4.0 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 ORY49754.1 - 1.4e-38 132.5 6.1 1.4e-38 132.5 1.1 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY49754.1 - 4.8e-33 113.8 14.8 3.7e-29 101.2 4.2 4.5 3 2 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.15 ORY49755.1 - 2.4e-39 134.0 14.7 3.9e-38 130.1 1.3 4.0 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.22 ORY49755.1 - 1.5e-38 132.4 1.3 1.5e-38 132.4 1.3 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 ORY49755.1 - 1.1e-33 115.8 15.6 7.1e-29 100.3 4.1 4.5 3 2 0 3 3 3 3 Multicopper oxidase MFS_1 PF07690.16 ORY49757.1 - 2.7e-27 95.6 28.9 4.1e-27 95.0 28.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily ubiquitin PF00240.23 ORY49758.1 - 1.9e-05 24.3 0.0 4.5e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family HET PF06985.11 ORY49758.1 - 0.0063 16.9 0.7 0.22 11.9 0.7 2.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ubiquitin_2 PF14560.6 ORY49758.1 - 0.017 15.5 0.0 0.049 14.1 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain VIT1 PF01988.19 ORY49759.1 - 1.3e-41 142.8 1.9 2.1e-41 142.2 0.0 1.9 2 0 0 2 2 2 1 VIT family YTH PF04146.15 ORY49760.1 - 2.2e-31 109.1 0.0 1.4e-23 83.7 0.0 4.5 3 1 0 3 3 3 2 YT521-B-like domain Acyltransferase PF01553.21 ORY49761.1 - 3.5e-11 42.9 0.0 5e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DAGAT PF03982.13 ORY49761.1 - 5.3e-06 25.6 0.0 1.1e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 Diacylglycerol acyltransferase DAGAT PF03982.13 ORY49762.1 - 2.7e-14 52.8 0.0 1.3e-07 30.9 0.0 2.7 3 0 0 3 3 3 2 Diacylglycerol acyltransferase Acyltransferase PF01553.21 ORY49762.1 - 9e-12 44.8 0.0 0.0074 15.9 0.0 3.2 2 1 0 3 3 3 3 Acyltransferase AOX PF01786.17 ORY49763.1 - 1.8e-88 295.8 0.1 2.3e-88 295.4 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 ORY49763.1 - 0.1 12.4 0.1 0.59 9.9 0.1 2.0 1 1 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 AOX PF01786.17 ORY49764.1 - 8.5e-93 309.9 1.7 1e-92 309.6 1.7 1.0 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 ORY49764.1 - 0.034 13.9 0.2 0.078 12.8 0.2 1.5 1 1 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Peptidase_S66C PF17676.1 ORY49764.1 - 0.086 13.4 0.0 0.38 11.3 0.0 1.9 2 0 0 2 2 2 0 LD-carboxypeptidase C-terminal domain AOX PF01786.17 ORY49765.1 - 6.9e-92 306.9 1.0 8.5e-92 306.6 1.0 1.1 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 ORY49765.1 - 0.011 15.5 0.1 0.021 14.6 0.1 1.4 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 Peptidase_S66C PF17676.1 ORY49765.1 - 0.034 14.7 0.0 0.1 13.2 0.0 1.7 2 0 0 2 2 2 0 LD-carboxypeptidase C-terminal domain HTH_9 PF08221.11 ORY49766.1 - 4.4e-24 84.3 2.1 1.5e-18 66.7 0.1 3.4 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 ORY49766.1 - 4.7e-22 79.0 1.5 2.8e-20 73.2 0.6 3.2 2 1 0 2 2 2 1 RNA polymerase III subunit RPC82 TFIIE_alpha PF02002.17 ORY49766.1 - 8.9e-11 41.6 1.4 0.0017 18.2 0.0 3.8 4 0 0 4 4 4 2 TFIIE alpha subunit Phage_rep_O PF04492.13 ORY49766.1 - 0.011 16.3 0.1 4.1 8.0 0.0 3.4 3 0 0 3 3 3 0 Bacteriophage replication protein O DprA_WH PF17782.1 ORY49766.1 - 0.1 12.7 0.1 0.25 11.5 0.1 1.6 1 0 0 1 1 1 0 DprA winged helix domain HTH_IclR PF09339.10 ORY49766.1 - 0.42 10.5 0.1 0.42 10.5 0.1 2.5 3 0 0 3 3 3 0 IclR helix-turn-helix domain Cob_adeno_trans PF01923.18 ORY49767.1 - 0.018 15.2 4.0 0.019 15.1 0.4 2.5 2 1 1 3 3 3 0 Cobalamin adenosyltransferase DUF1192 PF06698.11 ORY49767.1 - 0.02 14.9 5.3 5.4 7.2 0.2 4.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Cep57_CLD_2 PF14197.6 ORY49767.1 - 0.037 14.1 8.5 0.075 13.1 0.6 3.5 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 RPAP1_N PF08621.10 ORY49767.1 - 0.061 13.1 2.4 0.67 9.8 0.3 3.0 2 0 0 2 2 2 0 RPAP1-like, N-terminal Img2 PF05046.14 ORY49767.1 - 0.1 12.9 1.3 4.9 7.5 0.1 2.6 2 1 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) PilJ PF13675.6 ORY49767.1 - 0.14 12.2 0.2 0.14 12.2 0.2 2.7 2 1 2 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term Allexi_40kDa PF05549.11 ORY49767.1 - 0.27 10.7 4.2 0.25 10.8 0.5 2.4 1 1 1 2 2 2 0 Allexivirus 40kDa protein FlaC_arch PF05377.11 ORY49767.1 - 0.59 10.6 11.0 0.21 12.0 0.5 4.1 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 ORY49767.1 - 0.8 9.0 5.7 1.1 8.5 4.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Vac_Fusion PF02346.16 ORY49767.1 - 1.6 8.4 5.3 9.3 6.0 0.0 3.4 4 0 0 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 SpoOE-like PF09388.10 ORY49767.1 - 3.4 7.6 8.2 3.6 7.5 0.1 3.2 3 0 0 3 3 3 0 Spo0E like sporulation regulatory protein Cep57_MT_bd PF06657.13 ORY49767.1 - 7.1 7.2 15.6 1.4 9.4 0.8 4.1 3 2 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Ferredoxin_N PF16947.5 ORY49768.1 - 0.048 13.8 0.7 0.088 12.9 0.2 1.7 2 0 0 2 2 2 0 N-terminal region of 4Fe-4S ferredoxin iron-sulfur binding TMEM171 PF15471.6 ORY49768.1 - 7.1 5.5 6.7 3.2 6.7 0.9 2.1 1 1 1 2 2 2 0 Transmembrane protein family 171 4HBT PF03061.22 ORY49769.1 - 2.1e-06 28.0 1.2 0.0051 17.1 0.2 2.4 2 0 0 2 2 2 2 Thioesterase superfamily Ricin_B_lectin PF00652.22 ORY49771.1 - 1.1e-18 67.7 3.8 1.5e-12 47.9 0.5 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 ORY49771.1 - 3.3e-18 66.2 8.4 9e-10 39.2 0.9 2.7 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like DUF563 PF04577.14 ORY49772.1 - 3e-10 40.6 0.1 5.6e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Glycos_transf_2 PF00535.26 ORY49773.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 2 DUF3681 PF12442.8 ORY49773.1 - 0.02 15.4 2.9 0.022 15.2 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) Glyco_trans_2_3 PF13632.6 ORY49773.1 - 0.098 12.6 0.1 0.098 12.6 0.1 3.5 4 1 0 4 4 4 0 Glycosyl transferase family group 2 WD40 PF00400.32 ORY49775.1 - 0.0016 19.2 1.0 0.78 10.7 0.2 2.3 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY49777.1 - 1.1e-05 25.6 0.5 0.077 13.3 0.1 3.9 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 ORY49777.1 - 0.0072 15.4 0.1 0.0072 15.4 0.1 2.6 4 0 0 4 4 4 1 Coatomer WD associated region Clathrin PF00637.20 ORY49777.1 - 0.032 14.1 1.0 7.9 6.3 0.0 3.4 3 0 0 3 3 3 0 Region in Clathrin and VPS Chlam_OMP3 PF03503.13 ORY49777.1 - 1.5 9.2 7.6 0.68 10.3 3.6 2.3 2 0 0 2 2 2 0 Chlamydia cysteine-rich outer membrane protein 3 DZR PF12773.7 ORY49777.1 - 1.8 8.6 10.0 6.3 6.9 10.0 2.0 1 1 0 1 1 1 0 Double zinc ribbon Glyco_trans_2_3 PF13632.6 ORY49778.1 - 1.3e-08 35.0 2.3 1.3e-08 35.0 2.3 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY49778.1 - 0.00012 22.1 0.0 0.00024 21.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF3681 PF12442.8 ORY49778.1 - 0.081 13.4 1.2 0.17 12.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) Glycos_transf_2 PF00535.26 ORY49778.1 - 0.095 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 zf-MYND PF01753.18 ORY49779.1 - 1.3e-09 37.9 15.5 3.3e-09 36.7 15.5 1.7 1 0 0 1 1 1 1 MYND finger TAF6_C PF07571.13 ORY49779.1 - 0.064 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain 4HBT PF03061.22 ORY49782.1 - 1.1e-07 32.1 0.4 0.00045 20.5 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily PAPS_reduct PF01507.19 ORY49783.1 - 3.6e-20 72.7 0.0 4.7e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family PAPS_reduct PF01507.19 ORY49784.1 - 3.9e-08 33.5 0.0 5.2e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family AAA PF00004.29 ORY49785.1 - 5.9e-38 130.3 0.0 7.2e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY49785.1 - 2.9e-07 31.0 0.2 0.00049 20.5 0.0 2.2 1 1 1 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 ORY49785.1 - 6.7e-07 29.2 0.0 1.2e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 ORY49785.1 - 4.1e-06 26.8 0.1 5.1e-05 23.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ORY49785.1 - 2.4e-05 24.5 0.0 3.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activat PF00158.26 ORY49785.1 - 2.7e-05 23.9 0.2 0.0012 18.5 0.2 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.6 ORY49785.1 - 2.9e-05 24.3 0.0 0.0001 22.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY49785.1 - 4.7e-05 23.7 0.3 0.0043 17.3 0.1 2.5 1 1 2 3 3 3 1 AAA domain IstB_IS21 PF01695.17 ORY49785.1 - 0.00027 20.7 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 ORY49785.1 - 0.00054 19.4 0.3 0.0019 17.6 0.1 1.8 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 ORY49785.1 - 0.0012 18.0 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 ORY49785.1 - 0.0016 18.5 0.0 0.0023 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ORY49785.1 - 0.0016 18.1 0.3 0.03 13.9 0.1 2.2 1 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ORY49785.1 - 0.0024 18.2 0.0 0.0074 16.7 0.0 1.8 1 1 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 ORY49785.1 - 0.0028 17.4 0.0 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ORY49785.1 - 0.0039 16.7 0.0 0.0088 15.6 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 ORY49785.1 - 0.0049 17.4 0.0 0.0069 16.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 ORY49785.1 - 0.0057 15.9 0.1 0.0088 15.3 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain NACHT PF05729.12 ORY49785.1 - 0.0076 16.2 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_3 PF07726.11 ORY49785.1 - 0.014 15.3 0.1 0.034 14.0 0.1 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 ORY49785.1 - 0.021 13.9 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase PF06745.13 ORY49785.1 - 0.022 14.1 0.1 0.28 10.5 0.0 2.0 1 1 1 2 2 2 0 KaiC TniB PF05621.11 ORY49785.1 - 0.024 14.0 0.0 0.31 10.4 0.0 2.2 1 1 0 2 2 2 0 Bacterial TniB protein NTPase_1 PF03266.15 ORY49785.1 - 0.031 14.2 0.2 0.13 12.2 0.1 1.8 1 1 1 2 2 2 0 NTPase PhoH PF02562.16 ORY49785.1 - 0.036 13.5 0.0 0.064 12.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 ORY49785.1 - 0.043 13.8 0.0 0.12 12.4 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SelB-wing_1 PF09105.10 ORY49785.1 - 0.057 13.4 0.2 13 5.8 0.1 2.6 2 0 0 2 2 2 0 Elongation factor SelB, winged helix AAA_28 PF13521.6 ORY49785.1 - 0.062 13.5 0.1 0.13 12.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain Guanylate_kin PF00625.21 ORY49785.1 - 0.089 12.5 0.0 0.25 11.0 0.0 1.7 1 1 1 2 2 2 0 Guanylate kinase AAA_30 PF13604.6 ORY49785.1 - 0.093 12.4 0.1 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.14 ORY49785.1 - 0.094 11.9 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase KTI12 PF08433.10 ORY49785.1 - 0.11 12.0 0.0 4.5 6.6 0.0 2.0 1 1 1 2 2 2 0 Chromatin associated protein KTI12 AAA_11 PF13086.6 ORY49785.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORY49785.1 - 0.2 10.9 0.0 0.4 9.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.9 ORY49785.1 - 0.22 10.7 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Sel1 PF08238.12 ORY49786.1 - 6e-26 90.3 1.7 1.6e-05 25.4 0.2 5.0 5 0 0 5 5 5 5 Sel1 repeat EF1_GNE PF00736.19 ORY49787.1 - 2e-32 111.2 0.8 2e-32 111.2 0.8 2.7 3 0 0 3 3 3 1 EF-1 guanine nucleotide exchange domain tRNA-synt_His PF13393.6 ORY49787.1 - 8.1e-25 87.7 0.0 6.1e-20 71.7 0.0 2.6 2 1 1 3 3 3 2 Histidyl-tRNA synthetase EF-1_beta_acid PF10587.9 ORY49787.1 - 8.9e-12 45.2 9.3 2.4e-11 43.8 6.0 2.8 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region HGTP_anticodon PF03129.20 ORY49787.1 - 6.1e-09 35.9 0.5 1.4e-08 34.8 0.5 1.7 1 0 0 1 1 1 1 Anticodon binding domain WHEP-TRS PF00458.20 ORY49787.1 - 9.6e-05 22.5 2.2 9.6e-05 22.5 2.2 2.7 2 0 0 2 2 2 1 WHEP-TRS domain 3HCDH_N PF02737.18 ORY49787.1 - 0.041 13.8 0.5 0.21 11.5 0.5 2.3 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MinC_N PF05209.13 ORY49787.1 - 0.15 12.0 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain tRNA-synt_2 PF00152.20 ORY49787.1 - 0.22 10.6 0.7 16 4.4 0.0 2.6 2 1 1 3 3 3 0 tRNA synthetases class II (D, K and N) SR-25 PF10500.9 ORY49787.1 - 0.38 10.3 4.5 0.85 9.2 4.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FlxA PF14282.6 ORY49787.1 - 0.72 9.9 3.9 1.6 8.7 3.9 1.5 1 0 0 1 1 1 0 FlxA-like protein YabA PF06156.13 ORY49788.1 - 0.018 15.7 0.5 0.05 14.3 0.2 1.8 2 0 0 2 2 2 0 Initiation control protein YabA Tri3 PF07428.11 ORY49788.1 - 0.05 12.5 0.0 0.062 12.2 0.0 1.1 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 KIAA1430 PF13879.6 ORY49788.1 - 0.49 11.2 5.0 1 10.1 3.4 2.1 2 1 0 2 2 2 0 KIAA1430 homologue DUF5082 PF16888.5 ORY49789.1 - 0.00049 20.4 11.2 0.093 13.0 3.4 3.6 4 0 0 4 4 3 2 Domain of unknown function (DUF5082) Fez1 PF06818.15 ORY49789.1 - 0.0034 17.9 7.4 0.64 10.4 0.1 2.5 2 1 0 2 2 2 2 Fez1 HALZ PF02183.18 ORY49789.1 - 0.0045 17.2 6.9 0.026 14.7 0.0 4.4 5 0 0 5 5 4 1 Homeobox associated leucine zipper CREPT PF16566.5 ORY49789.1 - 0.0062 16.7 8.1 0.015 15.5 3.3 2.5 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour JIP_LZII PF16471.5 ORY49789.1 - 0.0078 16.4 0.6 0.0078 16.4 0.6 4.8 5 1 1 6 6 5 1 JNK-interacting protein leucine zipper II KLRAQ PF10205.9 ORY49789.1 - 0.0097 16.1 1.9 0.039 14.2 1.9 2.1 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein Jnk-SapK_ap_N PF09744.9 ORY49789.1 - 0.013 15.7 6.6 0.013 15.7 6.6 3.6 4 0 0 4 4 4 0 JNK_SAPK-associated protein-1 Exonuc_VII_L PF02601.15 ORY49789.1 - 0.014 15.0 6.0 2.1 7.8 4.4 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit KASH_CCD PF14662.6 ORY49789.1 - 0.033 14.0 16.2 0.1 12.4 8.5 3.4 3 1 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH Mito_fiss_reg PF05308.11 ORY49789.1 - 0.052 13.6 14.0 0.17 11.9 1.9 2.9 3 0 0 3 3 3 0 Mitochondrial fission regulator DAHP_snth_FXD PF18152.1 ORY49789.1 - 0.12 12.3 0.4 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 DAHP synthase ferredoxin-like domain Spc7 PF08317.11 ORY49789.1 - 0.15 10.9 12.3 3.1 6.6 4.6 3.5 4 0 0 4 4 4 0 Spc7 kinetochore protein COG2 PF06148.11 ORY49789.1 - 0.24 11.5 4.0 2.6 8.1 0.0 3.0 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HAUS-augmin3 PF14932.6 ORY49789.1 - 0.34 10.5 8.9 5.9 6.4 0.1 2.5 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 APG6_N PF17675.1 ORY49789.1 - 0.43 11.1 16.4 0.81 10.2 4.8 3.5 3 2 0 3 3 3 0 Apg6 coiled-coil region DUF724 PF05266.14 ORY49789.1 - 0.71 9.7 5.1 1.8 8.4 2.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) PI_PP_I PF18363.1 ORY49789.1 - 1.5 9.0 3.9 11 6.2 0.4 3.2 3 0 0 3 3 3 0 Phosphoinositide phosphatase insertion domain TMPIT PF07851.13 ORY49789.1 - 1.6 7.9 7.9 11 5.1 0.0 2.4 2 0 0 2 2 2 0 TMPIT-like protein GIT_CC PF16559.5 ORY49789.1 - 2 8.4 10.7 0.17 11.8 1.0 3.5 3 1 1 4 4 4 0 GIT coiled-coil Rho guanine nucleotide exchange factor Fib_alpha PF08702.10 ORY49789.1 - 2.1 8.6 9.9 8 6.6 0.0 3.0 4 0 0 4 4 3 0 Fibrinogen alpha/beta chain family ADIP PF11559.8 ORY49789.1 - 2.4 8.2 21.2 0.5 10.4 6.9 3.0 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF773 PF05600.12 ORY49789.1 - 2.8 6.6 8.5 24 3.5 4.8 2.7 3 0 0 3 3 3 0 CDK5 regulatory subunit-associated protein 3 Prominin PF05478.11 ORY49789.1 - 3.9 5.3 10.1 2.6 5.9 3.9 2.7 3 0 0 3 3 3 0 Prominin DUF1664 PF07889.12 ORY49789.1 - 5 7.2 10.1 11 6.1 0.1 4.1 3 2 2 5 5 5 0 Protein of unknown function (DUF1664) Cep57_MT_bd PF06657.13 ORY49789.1 - 8.6 6.9 10.6 3.6 8.1 0.0 4.5 4 1 2 6 6 6 0 Centrosome microtubule-binding domain of Cep57 CCDC154 PF15450.6 ORY49790.1 - 0.0016 17.1 2.1 0.0019 16.8 2.1 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 154 Cep57_CLD PF14073.6 ORY49790.1 - 0.0067 16.5 6.2 0.01 15.9 6.2 1.2 1 0 0 1 1 1 1 Centrosome localisation domain of Cep57 EzrA PF06160.12 ORY49790.1 - 0.0088 14.3 1.9 0.011 14.0 1.9 1.2 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Laminin_II PF06009.12 ORY49790.1 - 0.009 16.0 0.3 0.03 14.3 0.7 1.6 2 0 0 2 2 2 1 Laminin Domain II ATG16 PF08614.11 ORY49790.1 - 0.013 15.7 6.8 0.017 15.3 6.8 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 ORY49790.1 - 0.021 14.8 6.9 0.031 14.3 6.9 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding KxDL PF10241.9 ORY49790.1 - 0.026 14.8 3.4 0.74 10.1 1.0 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein Fib_alpha PF08702.10 ORY49790.1 - 0.031 14.4 0.4 0.045 13.9 0.4 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family TMPIT PF07851.13 ORY49790.1 - 0.047 12.9 0.5 0.056 12.7 0.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF3450 PF11932.8 ORY49790.1 - 0.065 12.5 1.2 0.084 12.2 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.12 ORY49790.1 - 0.1 13.1 0.1 0.37 11.3 0.1 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein GAS PF13851.6 ORY49790.1 - 0.18 11.1 6.4 0.25 10.7 6.4 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Pinin_SDK_memA PF04696.13 ORY49790.1 - 0.29 11.2 5.9 0.41 10.7 5.9 1.2 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Vac_Fusion PF02346.16 ORY49790.1 - 0.75 9.5 5.0 2.2 8.0 0.6 2.5 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 TPR_2 PF07719.17 ORY49791.1 - 8.2e-09 34.9 7.0 0.0002 21.2 0.1 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY49791.1 - 1.2e-08 34.4 8.8 0.00032 20.4 0.3 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY49791.1 - 9.4e-08 31.7 8.9 0.11 12.7 0.1 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY49791.1 - 3.3e-06 27.3 6.4 0.00049 20.3 2.0 4.2 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY49791.1 - 8.4e-06 25.5 3.8 0.37 10.9 0.1 4.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY49791.1 - 3.6e-05 24.3 0.4 0.61 10.8 0.1 4.2 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY49791.1 - 7.9e-05 23.2 1.7 4.3 8.4 0.1 4.9 2 1 4 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 ORY49791.1 - 0.00015 22.2 4.7 5.4 7.9 0.0 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat Coatomer_E PF04733.14 ORY49791.1 - 0.00052 19.5 2.5 0.012 15.1 0.2 2.4 1 1 1 2 2 2 1 Coatomer epsilon subunit TPR_11 PF13414.6 ORY49791.1 - 0.0012 18.5 7.0 0.0019 17.9 0.4 3.6 4 0 0 4 4 4 1 TPR repeat TPR_10 PF13374.6 ORY49791.1 - 0.0014 18.4 1.7 0.068 13.1 0.2 3.4 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY49791.1 - 0.0014 18.0 1.5 0.3 10.4 0.1 3.1 1 1 3 4 4 4 1 MalT-like TPR region ANAPC3 PF12895.7 ORY49791.1 - 0.0017 18.5 4.4 0.25 11.6 0.4 3.5 1 1 3 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 HrpB1_HrpK PF09613.10 ORY49791.1 - 0.043 13.5 0.1 0.23 11.1 0.0 2.1 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_19 PF14559.6 ORY49791.1 - 0.073 13.6 9.2 0.24 11.9 0.4 4.3 3 2 2 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 ORY49791.1 - 0.27 11.3 4.1 7 6.8 0.1 3.3 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain ERCC3_RAD25_C PF16203.5 ORY49792.1 - 1.3e-96 322.6 0.2 2.3e-96 321.8 0.2 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 ORY49792.1 - 8.4e-21 74.4 0.0 1.6e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY49792.1 - 8.5e-08 32.4 0.0 1.7e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 ORY49792.1 - 1.7e-05 23.7 0.0 8.5e-05 21.4 0.0 1.8 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY49792.1 - 9.3e-05 22.7 2.2 0.00021 21.6 0.1 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY49792.1 - 0.005 16.6 0.0 0.034 13.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AMNp_N PF10423.9 ORY49792.1 - 0.044 13.4 0.1 0.28 10.8 0.0 2.0 2 0 0 2 2 2 0 Bacterial AMP nucleoside phosphorylase N-terminus CMS1 PF14617.6 ORY49792.1 - 0.059 12.7 0.7 0.5 9.7 0.0 2.2 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Retrotrans_gag PF03732.17 ORY49792.1 - 0.21 11.9 0.4 0.65 10.3 0.0 1.9 2 0 0 2 2 2 0 Retrotransposon gag protein MFS_1 PF07690.16 ORY49793.1 - 1.3e-19 70.4 20.7 5.4e-18 65.0 20.0 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily 7tm_1 PF00001.21 ORY49795.1 - 0.014 14.8 2.5 0.04 13.2 2.5 1.9 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Alfin PF12165.8 ORY49795.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Alfin Internalin_N PF12354.8 ORY49797.1 - 0.19 11.9 0.1 0.52 10.4 0.1 1.8 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal 7tm_1 PF00001.21 ORY49797.1 - 0.98 8.7 6.1 2.4 7.4 6.1 1.7 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) FYVE PF01363.21 ORY49798.1 - 4.8e-17 61.9 10.8 8.3e-17 61.1 10.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 ORY49798.1 - 0.0025 18.0 8.3 0.0048 17.1 8.3 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger IMS PF00817.20 ORY49798.1 - 0.0037 17.3 0.1 0.0074 16.3 0.1 1.6 1 1 0 1 1 1 1 impB/mucB/samB family PH_13 PF16652.5 ORY49798.1 - 0.064 13.1 0.0 0.094 12.5 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain zf-RING_2 PF13639.6 ORY49798.1 - 1.3 9.5 12.1 2.8 8.3 12.1 1.7 1 0 0 1 1 1 0 Ring finger domain DivIVA PF05103.13 ORY49799.1 - 0.0026 17.9 4.5 0.0026 17.9 4.5 3.6 2 1 1 3 3 3 1 DivIVA protein BLOC1_2 PF10046.9 ORY49799.1 - 0.0061 16.8 4.9 0.0061 16.8 4.9 3.8 3 2 1 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 PKcGMP_CC PF16808.5 ORY49799.1 - 0.014 15.2 0.4 0.014 15.2 0.4 4.4 4 1 0 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SAB PF04382.13 ORY49799.1 - 0.032 14.3 0.4 0.032 14.3 0.4 3.3 3 0 0 3 3 3 0 SAB domain OmpH PF03938.14 ORY49799.1 - 0.12 12.8 29.7 0.9 9.9 6.9 3.2 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Spc24 PF08286.11 ORY49799.1 - 0.26 11.5 23.6 0.14 12.4 3.8 4.0 3 1 1 4 4 4 0 Spc24 subunit of Ndc80 DUF4515 PF14988.6 ORY49799.1 - 0.78 9.5 35.3 2.7 7.8 7.5 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4515) SlyX PF04102.12 ORY49799.1 - 0.86 10.3 19.0 0.35 11.5 0.3 4.8 4 2 0 4 4 4 0 SlyX Cnn_1N PF07989.11 ORY49799.1 - 0.96 9.6 27.5 1.4 9.1 1.0 3.6 3 1 0 3 3 3 0 Centrosomin N-terminal motif 1 ACP_PD PF04336.12 ORY49799.1 - 1.1 9.7 6.9 8 6.9 0.9 3.2 2 1 0 3 3 3 0 Acyl carrier protein phosphodiesterase Tropomyosin_1 PF12718.7 ORY49799.1 - 2.5 8.2 35.8 6.6 6.9 13.9 3.7 2 1 1 3 3 3 0 Tropomyosin like FAST_2 PF08368.12 ORY49799.1 - 2.7 8.8 6.7 9.1 7.1 0.5 3.3 2 2 1 3 3 3 0 FAST kinase-like protein, subdomain 2 Jnk-SapK_ap_N PF09744.9 ORY49799.1 - 3.6 7.8 35.0 10 6.3 12.9 3.2 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 KfrA_N PF11740.8 ORY49799.1 - 3.6 8.3 18.2 6.4 7.5 0.4 3.7 2 1 1 3 3 3 0 Plasmid replication region DNA-binding N-term TPR_MLP1_2 PF07926.12 ORY49799.1 - 5.1 7.2 37.7 2.6 8.1 10.1 3.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein YabA PF06156.13 ORY49799.1 - 5.2 7.8 26.0 8.2 7.1 4.4 4.0 2 2 2 4 4 4 0 Initiation control protein YabA Lectin_N PF03954.14 ORY49799.1 - 6 6.6 17.4 3.1 7.6 3.3 3.3 3 1 0 3 3 3 0 Hepatic lectin, N-terminal domain ABC_tran_CTD PF16326.5 ORY49799.1 - 7.2 6.9 26.0 5.1 7.4 5.4 4.1 3 2 0 3 3 3 0 ABC transporter C-terminal domain Spectrin PF00435.21 ORY49799.1 - 8.6 6.9 25.3 0.25 11.8 3.6 3.6 3 1 0 3 3 3 0 Spectrin repeat bZIP_1 PF00170.21 ORY49799.1 - 9 6.5 32.3 0.83 9.8 0.9 4.9 4 1 1 5 5 5 0 bZIP transcription factor DSHCT PF08148.12 ORY49800.1 - 2.4e-38 131.4 1.0 2.3e-28 98.9 0.1 2.6 1 1 1 2 2 2 2 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 ORY49800.1 - 4.3e-28 99.0 0.1 7.1e-28 98.3 0.1 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 ORY49800.1 - 2.5e-07 30.6 0.1 1.4e-05 25.0 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY49800.1 - 1.7e-06 28.4 0.0 7.4e-06 26.3 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY49800.1 - 0.012 15.6 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CN_hydrolase PF00795.22 ORY49801.1 - 6.9e-31 107.5 0.0 9e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase APG5 PF04106.12 ORY49802.1 - 1.2e-46 159.2 0.0 4.1e-46 157.4 0.0 1.8 1 1 0 1 1 1 1 Autophagy protein Apg5 HSP20 PF00011.21 ORY49804.1 - 5.9e-27 93.8 1.9 7e-27 93.6 1.9 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORY49804.1 - 5.8e-13 48.2 0.0 8.3e-13 47.7 0.0 1.2 1 0 0 1 1 1 1 HSP20-like domain found in ArsA DUF4097 PF13349.6 ORY49804.1 - 0.0013 18.2 0.8 0.0016 17.8 0.8 1.1 1 0 0 1 1 1 1 Putative adhesin Nup160 PF11715.8 ORY49804.1 - 0.013 14.1 0.0 0.014 14.1 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 CS PF04969.16 ORY49804.1 - 0.017 16.1 1.8 0.039 15.0 1.7 1.6 1 1 1 2 2 2 0 CS domain BON PF04972.17 ORY49804.1 - 0.041 14.2 0.9 0.11 12.8 0.5 1.9 2 0 0 2 2 2 0 BON domain WD40 PF00400.32 ORY49805.1 - 4.2e-17 62.2 4.1 4.9e-08 33.5 0.3 6.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Pkinase PF00069.25 ORY49805.1 - 1.5e-13 50.8 0.0 2.7e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 ORY49805.1 - 1.4e-12 46.7 0.7 0.002 18.2 0.1 5.8 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 ORY49805.1 - 1.7e-07 31.5 0.0 0.0013 19.1 0.0 4.3 2 2 3 5 5 5 1 HEAT repeats Pkinase_Tyr PF07714.17 ORY49805.1 - 3.3e-07 29.9 0.0 5.7e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Cnd1 PF12717.7 ORY49805.1 - 7.4e-06 26.1 1.8 0.06 13.4 0.6 3.5 1 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 ORY49805.1 - 0.0005 20.5 0.0 0.017 15.6 0.0 3.3 3 0 0 3 3 3 1 HEAT-like repeat ANAPC4_WD40 PF12894.7 ORY49805.1 - 0.00088 19.5 0.1 3.2 8.1 0.0 3.0 2 1 1 3 3 2 2 Anaphase-promoting complex subunit 4 WD40 domain Tti2 PF10521.9 ORY49805.1 - 0.009 15.6 0.2 0.019 14.5 0.2 1.4 1 0 0 1 1 1 1 Tti2 family Vac14_Fab1_bd PF12755.7 ORY49805.1 - 0.043 14.4 0.6 0.79 10.4 0.2 3.0 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region Ge1_WD40 PF16529.5 ORY49805.1 - 0.11 11.5 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2202 PF09968.9 ORY49805.1 - 0.14 12.0 0.1 0.34 10.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein domain (DUF2202) PRKCSH_1 PF13015.6 ORY49806.1 - 0.00021 21.0 0.0 0.00092 18.9 0.0 1.9 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein WD40 PF00400.32 ORY49807.1 - 6.1e-11 42.7 2.2 3.8e-06 27.5 0.6 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY49807.1 - 0.0077 16.5 0.1 1.9 8.8 0.0 3.3 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF4637 PF15470.6 ORY49807.1 - 2 8.1 5.0 3.5 7.3 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF4709 PF15821.5 ORY49808.1 - 0.00023 21.4 3.0 0.00023 21.4 3.0 3.3 2 2 1 3 3 3 1 Domain of unknown function (DUF4709) DUF4407 PF14362.6 ORY49808.1 - 9 5.5 28.4 0.84 8.9 0.8 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) RRM_1 PF00076.22 ORY49810.1 - 2.2e-18 65.8 0.1 3.3e-18 65.3 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 ORY49810.1 - 5.3e-08 32.6 3.3 7.8e-08 32.1 3.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 ORY49810.1 - 7.2e-05 22.4 2.9 0.00013 21.6 2.9 1.4 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Nup35_RRM_2 PF14605.6 ORY49810.1 - 0.0015 18.5 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCHC_3 PF13917.6 ORY49810.1 - 0.0016 18.4 0.7 0.0022 17.9 0.7 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 ORY49810.1 - 0.01 15.6 1.2 0.015 15.1 1.2 1.3 1 0 0 1 1 1 0 Zinc knuckle T7SS_ESX_EspC PF10824.8 ORY49811.1 - 0.063 13.7 0.8 2.1 8.9 0.0 2.7 3 0 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm Galactosyl_T PF01762.21 ORY49812.1 - 2.4e-07 30.8 0.0 0.0033 17.3 0.0 2.3 1 1 1 2 2 2 2 Galactosyltransferase WD40 PF00400.32 ORY49813.1 - 4.4e-17 62.1 3.4 1.4e-08 35.2 0.2 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY49813.1 - 4.3e-05 23.7 0.0 0.11 12.9 0.0 3.3 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY49813.1 - 0.0017 17.1 0.1 0.3 9.7 0.0 2.5 1 1 2 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY49813.1 - 0.0032 16.8 0.0 0.0059 16.0 0.0 1.5 1 0 0 1 1 1 1 WD40-like domain Cytochrom_D1 PF02239.16 ORY49813.1 - 0.0072 14.9 0.0 0.031 12.8 0.0 1.9 1 1 1 2 2 2 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 ORY49813.1 - 0.041 12.8 0.0 0.22 10.4 0.0 2.0 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 ORY49813.1 - 0.05 13.6 0.0 9.6 6.3 0.0 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat TFIIA PF03153.13 ORY49814.1 - 0.32 11.0 6.4 0.35 10.8 6.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1279 PF06916.13 ORY49815.1 - 0.0004 20.9 0.2 0.00064 20.2 0.2 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) RAI1 PF08652.11 ORY49817.1 - 2.1e-21 75.9 0.0 4.1e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease CCDC53 PF10152.9 ORY49817.1 - 0.01 16.2 0.1 0.046 14.1 0.0 2.0 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF3537 PF12056.8 ORY49817.1 - 0.089 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) FOP_dimer PF09398.10 ORY49819.1 - 3.5e-08 33.6 0.0 5.7e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 FOP N terminal dimerisation domain LisH_2 PF16045.5 ORY49819.1 - 3.4e-06 26.0 0.0 4.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 LisH eIF3_subunit PF08597.10 ORY49820.1 - 4.4e-59 200.3 24.1 4.9e-59 200.2 24.1 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF4192 PF13830.6 ORY49820.1 - 0.011 15.8 2.7 0.015 15.4 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) BSP_II PF05432.11 ORY49820.1 - 0.15 11.8 15.3 0.21 11.3 15.3 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF327 PF03885.13 ORY49820.1 - 0.46 10.5 5.2 0.14 12.2 1.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF327) RR_TM4-6 PF06459.12 ORY49820.1 - 6.2 6.6 15.3 9.7 5.9 15.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 ORY49820.1 - 7.5 5.2 5.4 8.9 5.0 5.4 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 ORY49820.1 - 8.8 4.5 13.3 12 4.0 13.3 1.2 1 0 0 1 1 1 0 CDC45-like protein CNH PF00780.22 ORY49821.1 - 5.7e-43 147.5 0.0 8.1e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 ORY49821.1 - 1.8e-10 41.4 0.1 3.1e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain FIVAR PF07554.13 ORY49821.1 - 0.15 12.8 0.0 0.34 11.7 0.0 1.6 1 0 0 1 1 1 0 FIVAR domain HSP20 PF00011.21 ORY49822.1 - 2e-18 66.4 0.0 2.5e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 ORY49822.1 - 4e-10 39.1 0.0 6.6e-10 38.4 0.0 1.4 1 1 0 1 1 1 1 HSP20-like domain found in ArsA SRP-alpha_N PF04086.13 ORY49823.1 - 0.018 15.0 35.8 0.022 14.7 35.8 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Mitofilin PF09731.9 ORY49823.1 - 0.21 10.4 35.4 0.22 10.3 35.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein CbtA PF09490.10 ORY49823.1 - 1.6 8.4 12.2 7.4 6.3 12.2 2.0 1 1 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) G-patch PF01585.23 ORY49824.1 - 1.2e-14 53.9 4.2 1.2e-14 53.9 4.2 1.7 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 ORY49824.1 - 3.7e-05 23.7 1.5 3.7e-05 23.7 1.5 2.1 2 0 0 2 2 2 1 G-patch domain Thioredoxin PF00085.20 ORY49825.1 - 6.9e-29 99.9 0.3 8.3e-29 99.6 0.3 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY49825.1 - 2.7e-06 27.8 0.2 2.1e-05 24.9 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORY49825.1 - 4.6e-05 23.7 0.0 5.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 ORY49825.1 - 7.5e-05 22.6 0.2 8.5e-05 22.5 0.2 1.4 1 1 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 ORY49825.1 - 0.0012 18.3 0.0 0.0012 18.3 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 ORY49825.1 - 0.0015 18.3 0.0 0.0017 18.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.10 ORY49825.1 - 0.0018 18.0 0.3 0.0032 17.2 0.2 1.4 1 1 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.6 ORY49825.1 - 0.0039 17.3 0.3 0.007 16.5 0.3 1.4 1 1 0 1 1 1 1 Thioredoxin-like Asp PF00026.23 ORY49826.1 - 1.1e-56 192.6 0.2 9.7e-38 130.3 0.0 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY49826.1 - 1.6e-12 48.0 0.3 4.7e-10 40.0 0.3 2.2 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY49826.1 - 0.0049 16.7 0.0 0.0083 15.9 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 ORY49826.1 - 0.0086 16.7 0.0 0.27 11.9 0.0 2.6 1 1 0 1 1 1 1 Aspartyl protease Phage_T4_Ndd PF06591.11 ORY49826.1 - 0.086 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 T4-like phage nuclear disruption protein (Ndd) FAM196 PF15265.6 ORY49827.1 - 0.00061 19.4 0.0 0.00061 19.4 0.0 1.1 1 0 0 1 1 1 1 FAM196 family I_LWEQ PF01608.17 ORY49827.1 - 0.029 14.6 1.2 0.04 14.1 1.2 1.2 1 0 0 1 1 1 0 I/LWEQ domain Acetyltransf_7 PF13508.7 ORY49828.1 - 0.011 16.2 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY49828.1 - 0.23 11.4 0.0 0.59 10.1 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 ORY49829.1 - 9.8e-32 110.2 27.6 1.1e-31 110.0 27.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_MOT1 PF16983.5 ORY49829.1 - 7.4 7.0 7.7 15 6.0 0.1 3.0 3 1 0 3 3 3 0 Molybdate transporter of MFS superfamily TauD PF02668.16 ORY49830.1 - 7.6e-48 163.6 0.5 1.1e-47 163.1 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sec2p PF06428.11 ORY49831.1 - 9.2e-14 51.2 12.6 9.2e-14 51.2 12.6 2.7 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF3418 PF11898.8 ORY49831.1 - 2.4e-05 23.3 1.2 4.2e-05 22.4 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3418) Lipoprotein_7 PF01540.16 ORY49831.1 - 0.48 9.7 7.8 0.068 12.5 1.0 2.3 2 0 0 2 2 2 0 Adhesin lipoprotein Golgin_A5 PF09787.9 ORY49831.1 - 0.59 9.5 18.7 2.1 7.7 1.0 2.3 2 0 0 2 2 2 0 Golgin subfamily A member 5 Rab5-bind PF09311.11 ORY49831.1 - 1.3 8.3 16.7 1 8.7 10.9 2.1 2 0 0 2 2 2 0 Rabaptin-like protein Jnk-SapK_ap_N PF09744.9 ORY49831.1 - 4.6 7.5 20.4 0.27 11.4 12.1 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Copper-fist PF00649.18 ORY49832.1 - 8.6e-13 47.5 1.3 8.6e-13 47.5 1.3 2.0 1 1 0 1 1 1 1 Copper fist DNA binding domain Calpain_inhib PF00748.19 ORY49832.1 - 0.00014 22.4 1.2 0.00014 22.4 1.2 2.2 2 0 0 2 2 2 1 Calpain inhibitor Guanylate_cyc PF00211.20 ORY49833.1 - 4.5e-39 134.0 0.7 7.6e-39 133.2 0.2 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain FHA PF00498.26 ORY49833.1 - 3.6e-14 52.8 0.9 7.3e-14 51.9 0.9 1.5 1 0 0 1 1 1 1 FHA domain GAF_3 PF13492.6 ORY49833.1 - 6.5e-14 52.4 0.0 1.1e-13 51.6 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.6 ORY49833.1 - 7.6e-12 45.7 0.0 1.4e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 ORY49833.1 - 8.6e-11 42.6 0.0 1.6e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 GAF domain Yop-YscD_cpl PF16697.5 ORY49833.1 - 9.5e-10 38.7 0.0 2.8e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain GGDEF PF00990.21 ORY49833.1 - 0.017 14.8 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Diguanylate cyclase, GGDEF domain Opi1 PF08618.10 ORY49834.1 - 2.3e-18 66.6 1.8 2.9e-18 66.3 1.8 1.1 1 0 0 1 1 1 1 Transcription factor Opi1 DUF3391 PF11871.8 ORY49834.1 - 0.086 13.4 0.5 0.12 12.9 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) DUF3446 PF11928.8 ORY49834.1 - 1.8 8.9 10.2 0.93 9.8 8.0 1.6 2 0 0 2 2 2 0 Early growth response N-terminal domain M16C_assoc PF08367.11 ORY49837.1 - 3.2e-60 203.4 0.0 4.9e-60 202.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 ORY49837.1 - 1.1e-29 103.7 0.0 1e-19 71.3 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ORY49837.1 - 1.5e-07 31.5 0.1 1.5e-06 28.3 0.0 2.4 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Arf PF00025.21 ORY49838.1 - 3.9e-67 225.1 0.0 4.4e-67 224.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 ORY49838.1 - 9.6e-11 41.4 0.1 6.2e-07 28.9 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 ORY49838.1 - 3.5e-09 36.3 0.0 4.7e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 ORY49838.1 - 6.8e-09 35.5 0.0 8.6e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY49838.1 - 2.5e-08 34.2 0.0 6.7e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 ORY49838.1 - 1.7e-07 31.3 0.0 3e-07 30.5 0.0 1.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORY49838.1 - 6.5e-05 22.4 0.0 8.3e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORY49838.1 - 0.0024 17.4 0.0 0.076 12.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 ORY49838.1 - 0.051 13.3 0.0 0.21 11.3 0.0 2.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation CGI-121 PF08617.10 ORY49839.1 - 1.8e-39 135.4 0.8 2.1e-39 135.2 0.8 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 TIR_2 PF13676.6 ORY49840.1 - 1.2e-08 35.5 1.8 1.7e-07 31.9 0.0 3.6 4 0 0 4 4 4 1 TIR domain LRR_6 PF13516.6 ORY49840.1 - 0.00042 20.2 24.5 0.27 11.4 0.2 9.1 10 0 0 10 10 10 2 Leucine Rich repeat COG2 PF06148.11 ORY49840.1 - 0.004 17.2 1.7 0.031 14.3 1.8 2.3 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 SL4P PF17618.2 ORY49840.1 - 0.095 12.8 0.1 0.5 10.4 0.1 2.3 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein LRR_1 PF00560.33 ORY49840.1 - 0.14 12.8 3.2 34 5.5 0.0 5.3 4 1 0 4 4 4 0 Leucine Rich Repeat PNP_UDP_1 PF01048.20 ORY49841.1 - 7.4e-46 156.3 1.2 3.5e-45 154.1 1.2 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily PHD PF00628.29 ORY49842.1 - 1.5e-09 37.5 12.1 1.8e-09 37.3 9.3 2.3 2 0 0 2 2 2 1 PHD-finger zf-CW PF07496.15 ORY49842.1 - 0.071 13.2 4.7 0.28 11.3 4.7 2.1 1 0 0 1 1 1 0 CW-type Zinc Finger DUF5474 PF17568.2 ORY49842.1 - 0.088 12.9 0.0 18 5.5 0.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5474) PHD_2 PF13831.6 ORY49842.1 - 1.3 8.6 14.0 0.04 13.5 7.6 1.8 2 0 0 2 2 2 0 PHD-finger PHD_Oberon PF07227.11 ORY49842.1 - 1.6 8.6 7.0 0.96 9.3 4.1 2.1 2 0 0 2 2 2 0 PHD - plant homeodomain finger protein PK PF00224.21 ORY49843.1 - 4e-139 463.4 9.6 1.5e-136 454.9 9.6 2.3 1 1 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 ORY49843.1 - 2.5e-20 72.8 5.6 1.7e-18 67.0 5.6 2.9 1 1 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 ORY49843.1 - 0.00013 21.2 0.7 0.00033 19.9 0.7 1.8 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family YajC PF02699.15 ORY49843.1 - 0.0066 16.3 1.8 0.077 12.9 0.2 2.6 2 0 0 2 2 2 1 Preprotein translocase subunit DUF2009 PF09418.10 ORY49843.1 - 0.21 10.6 0.2 0.31 10.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Cupin_8 PF13621.6 ORY49844.1 - 3.2e-25 89.3 0.1 2.8e-24 86.2 0.1 2.0 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 ORY49844.1 - 5.8e-12 46.0 0.0 1.7e-11 44.6 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 ORY49844.1 - 0.0026 17.3 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_1 PF00190.22 ORY49844.1 - 0.065 12.8 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.11 ORY49844.1 - 0.088 12.5 0.0 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 Cupin domain LCM PF04072.14 ORY49845.1 - 1.1e-31 110.3 0.0 9.9e-30 103.9 0.0 2.1 2 0 0 2 2 2 2 Leucine carboxyl methyltransferase LRR_4 PF12799.7 ORY49846.1 - 0.0021 18.4 1.7 1 9.9 0.0 4.7 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORY49846.1 - 0.0022 17.8 0.0 0.005 16.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 ORY49846.1 - 0.057 13.5 1.1 0.81 9.9 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich repeat PCNA_C PF02747.15 ORY49847.1 - 9.5e-09 35.5 0.0 2e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain GspH PF12019.8 ORY49847.1 - 0.1 13.0 0.1 1.2 9.5 0.0 2.5 3 0 0 3 3 3 0 Type II transport protein GspH PROL5-SMR PF15621.6 ORY49847.1 - 1.2 9.7 7.9 0.37 11.3 0.8 3.0 3 0 0 3 3 3 0 Proline-rich submaxillary gland androgen-regulated family HAD PF12710.7 ORY49848.1 - 6e-18 65.9 0.0 8.3e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 ORY49848.1 - 2.8e-06 26.9 0.1 6.1e-06 25.8 0.1 1.5 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 ORY49848.1 - 0.00018 21.1 0.0 0.00036 20.1 0.0 1.6 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 ORY49848.1 - 0.0025 18.1 1.9 0.02 15.2 0.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY49848.1 - 0.0041 17.2 0.4 1.7 8.7 0.1 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PilJ_C PF18223.1 ORY49848.1 - 0.15 12.6 0.5 0.35 11.4 0.5 1.7 1 1 0 1 1 1 0 Pili PilJ C-terminal domain Choline_transpo PF04515.12 ORY49849.1 - 3.6e-36 125.0 20.3 1.1e-35 123.4 20.3 1.9 1 1 0 1 1 1 1 Plasma-membrane choline transporter PHD PF00628.29 ORY49850.1 - 7.7e-05 22.5 4.8 0.00013 21.8 4.8 1.4 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 ORY49850.1 - 0.05 13.2 1.5 0.1 12.2 1.5 1.5 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain APG17 PF04108.12 ORY49850.1 - 0.094 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg17 MbeD_MobD PF04899.12 ORY49850.1 - 0.16 12.1 2.7 0.2 11.8 0.2 2.3 3 0 0 3 3 3 0 MbeD/MobD like C1_1 PF00130.22 ORY49850.1 - 0.53 10.2 6.2 0.13 12.2 1.6 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 ORY49850.1 - 1.2 9.3 4.1 2.2 8.4 4.1 1.5 1 0 0 1 1 1 0 PHD-finger LRR_6 PF13516.6 ORY49851.1 - 0.00027 20.7 12.9 0.3 11.3 0.1 5.2 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 ORY49851.1 - 0.53 10.8 8.2 0.95 10.0 0.3 3.3 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Fe-ADH PF00465.19 ORY49852.1 - 2.5e-101 339.1 0.0 2.9e-101 338.9 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 ORY49852.1 - 2.8e-11 43.6 0.0 4.4e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase TAL_FSA PF00923.19 ORY49853.1 - 7.6e-78 261.8 0.5 1.7e-38 132.6 0.0 2.0 1 1 1 2 2 2 2 Transaldolase/Fructose-6-phosphate aldolase UPF0164 PF03687.13 ORY49853.1 - 0.042 12.6 0.1 0.19 10.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0164) DUF883 PF05957.13 ORY49855.1 - 0.62 10.7 4.3 0.47 11.1 0.4 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) AAA PF00004.29 ORY49857.1 - 1.4e-42 145.2 0.0 2.3e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY49857.1 - 2.6e-10 40.0 0.2 5.6e-10 38.9 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 ORY49857.1 - 2.1e-08 34.0 1.1 2.6e-08 33.7 0.1 1.7 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 ORY49857.1 - 1.3e-07 31.7 0.0 2.1e-06 27.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY49857.1 - 1.4e-06 28.8 0.0 0.00047 20.6 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 ORY49857.1 - 9.7e-06 25.8 0.0 2.2e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 ORY49857.1 - 1.2e-05 25.1 0.0 2.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORY49857.1 - 0.00024 21.4 0.1 0.0078 16.5 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY49857.1 - 0.00063 20.3 0.0 0.0015 19.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 ORY49857.1 - 0.0013 17.9 0.0 0.0031 16.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 ORY49857.1 - 0.0026 17.3 0.0 0.0049 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 ORY49857.1 - 0.0031 17.2 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ORY49857.1 - 0.0036 16.7 0.0 0.0082 15.5 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TsaE PF02367.17 ORY49857.1 - 0.0041 17.1 0.0 0.0074 16.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 ORY49857.1 - 0.008 16.3 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 ORY49857.1 - 0.0085 15.3 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 ORY49857.1 - 0.012 15.4 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 ORY49857.1 - 0.012 15.3 0.0 0.057 13.1 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 ORY49857.1 - 0.013 15.9 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 ORY49857.1 - 0.014 15.3 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 ORY49857.1 - 0.027 14.5 0.0 0.055 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 ORY49857.1 - 0.033 13.5 0.5 0.18 11.1 0.0 2.3 3 0 0 3 3 3 0 KaiC PhoH PF02562.16 ORY49857.1 - 0.04 13.4 0.1 0.071 12.6 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 ORY49857.1 - 0.041 14.1 0.0 0.085 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 ORY49857.1 - 0.042 13.5 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase AAA_30 PF13604.6 ORY49857.1 - 0.065 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ORY49857.1 - 0.082 12.8 0.1 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 ORY49857.1 - 0.09 11.9 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 ORY49857.1 - 0.099 12.2 0.5 0.21 11.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain Prot_ATP_OB_N PF17758.1 ORY49857.1 - 0.1 12.3 0.2 0.36 10.5 0.0 1.9 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_11 PF13086.6 ORY49857.1 - 0.2 11.4 0.4 0.58 9.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain End3 PF12761.7 ORY49857.1 - 0.22 11.7 1.6 0.38 10.9 1.6 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 zf-HIT PF04438.16 ORY49858.1 - 1.7e-10 40.6 12.4 2.8e-10 39.9 12.4 1.4 1 0 0 1 1 1 1 HIT zinc finger YL1_C PF08265.11 ORY49858.1 - 0.014 15.1 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain DUF4061 PF13270.6 ORY49858.1 - 0.057 13.7 0.2 0.18 12.1 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) CHCH PF06747.13 ORY49859.1 - 2.1e-05 24.5 3.6 2.1e-05 24.5 3.6 2.6 2 1 0 2 2 2 1 CHCH domain CLIP_SPH_mas PF18398.1 ORY49859.1 - 0.058 13.8 0.3 0.14 12.6 0.3 1.7 1 0 0 1 1 1 0 Clip-domain serine protease homolog masquerade DB PF01682.19 ORY49859.1 - 0.44 10.9 6.8 4.1 7.8 2.4 2.1 1 1 1 2 2 2 0 DB module Pet191_N PF10203.9 ORY49859.1 - 0.91 9.9 9.3 6 7.2 0.4 2.9 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 DUF3128 PF11326.8 ORY49859.1 - 7.3 7.0 10.5 6.3 7.2 4.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3128) CX9C PF16860.5 ORY49859.1 - 9.2 6.4 11.3 0.98 9.5 0.6 2.5 2 1 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Velvet PF11754.8 ORY49861.1 - 3.4e-26 92.7 0.0 3.7e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Velvet factor Reprolysin_2 PF13574.6 ORY49862.1 - 3.1e-29 102.3 5.5 7.8e-29 101.0 5.5 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 ORY49862.1 - 1.3e-28 100.1 3.9 2.5e-28 99.1 3.9 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 ORY49862.1 - 3e-28 99.3 6.9 3e-28 99.3 6.9 2.6 3 0 0 3 3 3 1 Metallo-peptidase family M12 Disintegrin PF00200.23 ORY49862.1 - 1e-16 61.5 27.3 1e-16 61.5 27.3 4.1 3 1 0 3 3 3 1 Disintegrin Reprolysin_3 PF13582.6 ORY49862.1 - 3.5e-09 37.2 0.4 3.5e-09 37.2 0.4 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 ORY49862.1 - 6.8e-05 22.9 7.8 0.00056 19.9 7.8 2.3 1 1 0 1 1 1 1 Reprolysin (M12B) family zinc metalloprotease Myc_target_1 PF15179.6 ORY49862.1 - 0.33 10.9 2.6 0.81 9.6 0.0 2.4 3 0 0 3 3 3 0 Myc target protein 1 Pkinase PF00069.25 ORY49863.1 - 1.8e-53 181.6 0.0 2.1e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY49863.1 - 1e-24 87.2 0.0 1.3e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY49863.1 - 3.9e-06 26.4 0.0 8e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY49863.1 - 0.01 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY49863.1 - 0.012 15.5 0.1 0.059 13.3 0.0 1.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family FTA2 PF13095.6 ORY49863.1 - 0.019 14.6 0.0 0.059 13.0 0.0 1.8 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 ORY49864.1 - 1e-55 189.0 0.0 1.2e-55 188.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY49864.1 - 2.1e-31 109.1 0.0 2.6e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY49864.1 - 8.4e-06 25.3 0.0 0.0008 18.8 0.0 2.4 2 1 0 2 2 2 2 Kinase-like APH PF01636.23 ORY49864.1 - 0.082 12.8 0.0 0.34 10.8 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 ORY49864.1 - 0.099 12.2 0.0 0.31 10.7 0.0 1.7 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 ORY49864.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DnaJ PF00226.31 ORY49865.1 - 2.4e-13 50.0 0.1 4.6e-13 49.1 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Cation_efflux PF01545.21 ORY49867.1 - 5.1e-40 137.3 3.2 7.6e-40 136.8 3.2 1.3 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORY49867.1 - 3.4e-24 84.8 6.3 2.7e-17 62.6 1.8 2.4 2 0 0 2 2 2 2 Dimerisation domain of Zinc Transporter Nit_Regul_Hom PF10126.9 ORY49867.1 - 0.052 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII PB1 PF00564.24 ORY49867.1 - 0.052 13.5 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 PB1 domain AA_permease_2 PF13520.6 ORY49868.1 - 3.9e-44 151.2 50.7 3.9e-44 151.2 50.7 1.5 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 ORY49868.1 - 1.3e-18 66.9 49.5 3.1e-18 65.6 49.4 1.6 1 1 0 1 1 1 1 Amino acid permease Y_phosphatase2 PF03162.13 ORY49869.1 - 3.4e-54 182.8 0.0 3.8e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 ORY49869.1 - 0.00048 20.2 0.0 0.0016 18.5 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 ORY49869.1 - 0.031 13.8 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 ORY49869.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.3 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain B9-C2 PF07162.11 ORY49870.1 - 3.2e-36 125.0 0.0 5.4e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Ldh_1_C PF02866.18 ORY49871.1 - 0.0012 18.8 0.0 0.0013 18.7 0.0 1.0 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain ABC_membrane PF00664.23 ORY49872.1 - 8.3e-42 143.7 7.0 1e-41 143.4 7.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 ORY49872.1 - 5.3e-22 78.8 0.0 2.1e-21 76.9 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 ORY49872.1 - 8.2e-05 23.0 0.0 0.00019 21.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 ORY49872.1 - 0.0022 17.9 0.0 0.0047 16.9 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Rad17 PF03215.15 ORY49872.1 - 0.0064 16.4 0.1 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 ORY49872.1 - 0.0064 16.8 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 ORY49872.1 - 0.0083 15.6 0.0 4.6 6.6 0.0 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY49872.1 - 0.0085 15.8 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 ORY49872.1 - 0.013 15.2 0.0 0.05 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 ORY49872.1 - 0.02 15.3 0.0 0.11 13.0 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 ORY49872.1 - 0.024 14.2 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY49872.1 - 0.054 13.9 0.0 0.77 10.2 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 ORY49872.1 - 0.09 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF3015 PF11220.8 ORY49872.1 - 0.1 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) AAA_21 PF13304.6 ORY49872.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 ORY49872.1 - 0.18 11.0 0.0 0.33 10.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin HMG_box PF00505.19 ORY49873.1 - 1.1e-22 80.2 1.7 1.5e-22 79.7 1.7 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY49873.1 - 2.5e-16 60.0 1.5 3.3e-16 59.6 1.5 1.2 1 0 0 1 1 1 1 HMG-box domain Rtt106 PF08512.12 ORY49874.1 - 1.4e-22 79.9 0.0 7.7e-21 74.3 0.0 2.8 3 0 0 3 3 3 1 Histone chaperone Rttp106-like SSrecog PF03531.14 ORY49874.1 - 7.8e-22 77.0 0.0 4e-21 74.7 0.0 2.2 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 ORY49874.1 - 7.9e-11 42.2 0.0 2.6e-09 37.4 0.0 2.4 2 0 0 2 2 2 1 POB3-like N-terminal PH domain Sde2_N_Ubi PF13019.6 ORY49875.1 - 9.7e-32 110.1 5.2 1.2e-31 109.8 5.2 1.0 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain SPC22 PF04573.12 ORY49876.1 - 1.6e-46 157.9 0.5 1.8e-46 157.8 0.5 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Thermopsin PF05317.11 ORY49876.1 - 0.0052 16.3 0.1 0.0055 16.2 0.1 1.1 1 0 0 1 1 1 1 Thermopsin zf-MIZ PF02891.20 ORY49877.1 - 7.6e-18 64.0 3.5 1.4e-17 63.2 3.5 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PINIT PF14324.6 ORY49877.1 - 2.8e-09 37.5 0.0 1e-08 35.6 0.0 2.0 1 1 0 1 1 1 1 PINIT domain SAP PF02037.27 ORY49877.1 - 1.4e-08 34.3 0.2 2.3e-08 33.6 0.2 1.3 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.8 ORY49877.1 - 0.00021 21.0 3.0 0.00055 19.7 3.0 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.6 ORY49878.1 - 1.2e-12 48.0 5.7 1.2e-12 48.0 5.7 1.9 2 0 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 ORY49878.1 - 4.9e-10 39.0 2.0 4.9e-10 39.0 2.0 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORY49878.1 - 1.8e-09 37.2 5.6 5.2e-09 35.8 5.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY49878.1 - 1.3e-07 31.4 5.6 1.3e-07 31.4 5.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY49878.1 - 9.9e-07 29.0 7.3 3.9e-06 27.1 7.3 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 ORY49878.1 - 6.4e-05 22.7 2.8 0.00012 21.9 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY49878.1 - 0.00011 22.1 3.4 0.00024 21.0 3.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY49878.1 - 0.023 14.7 3.1 0.023 14.7 3.1 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 ORY49878.1 - 0.034 14.2 1.7 0.086 12.9 1.7 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 ORY49878.1 - 0.055 13.3 5.0 0.11 12.4 5.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 ORY49878.1 - 0.1 12.8 4.4 0.27 11.4 4.4 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 ORY49878.1 - 0.18 11.5 2.5 0.48 10.1 2.5 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 ORY49878.1 - 0.21 11.7 5.7 0.51 10.5 5.7 1.7 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 ORY49878.1 - 0.63 10.0 3.6 1.2 9.1 3.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 ORY49878.1 - 6.9 7.1 7.4 2.1 8.7 4.3 1.9 2 0 0 2 2 1 0 RING-like domain NAT PF04768.13 ORY49879.1 - 1.2e-42 145.5 0.0 2.2e-42 144.6 0.0 1.4 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Acetyltransf_1 PF00583.25 ORY49879.1 - 0.03 14.6 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY49879.1 - 0.094 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY49879.1 - 0.22 11.5 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PDEase_I PF00233.19 ORY49880.1 - 2.2e-75 253.5 0.0 3.3e-75 252.9 0.0 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF5592 PF17332.2 ORY49880.1 - 0.025 15.1 0.4 0.025 15.1 0.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5592) DUF4870 PF09685.10 ORY49880.1 - 0.13 12.3 2.5 0.34 11.0 2.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) DUF4118 PF13493.6 ORY49880.1 - 0.99 9.2 12.2 0.48 10.2 9.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4118) Iso_dh PF00180.20 ORY49881.1 - 5.3e-71 239.6 0.1 6.3e-71 239.3 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Coatomer_WDAD PF04053.14 ORY49882.1 - 6.7e-168 559.3 0.3 1.1e-167 558.7 0.3 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 ORY49882.1 - 2.2e-35 120.0 9.2 1.6e-08 35.0 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY49882.1 - 4.7e-05 23.6 0.7 0.54 10.6 0.0 5.3 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 ORY49882.1 - 0.00065 19.7 0.1 2.3 8.3 0.0 4.2 3 2 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 ORY49882.1 - 0.0031 16.5 0.1 1.3 7.9 0.1 2.7 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORY49882.1 - 0.014 14.0 0.4 4.2 5.9 0.0 3.1 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Clathrin PF00637.20 ORY49882.1 - 0.074 12.9 0.3 13 5.6 0.1 2.3 2 0 0 2 2 2 0 Region in Clathrin and VPS AP_endonuc_2 PF01261.24 ORY49883.1 - 0.00027 20.5 0.0 0.0004 19.9 0.0 1.4 1 1 0 1 1 1 1 Xylose isomerase-like TIM barrel SET PF00856.28 ORY49884.1 - 0.0016 18.8 0.0 0.0053 17.2 0.0 1.8 1 1 0 1 1 1 1 SET domain CDC45 PF02724.14 ORY49885.1 - 0.0017 16.7 21.4 0.0021 16.4 21.4 1.2 1 0 0 1 1 1 1 CDC45-like protein PADR1 PF08063.12 ORY49885.1 - 0.0033 17.2 1.8 0.0055 16.5 1.8 1.3 1 0 0 1 1 1 1 PADR1 (NUC008) domain CDC27 PF09507.10 ORY49885.1 - 0.041 13.3 21.2 0.045 13.2 21.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SAP PF02037.27 ORY49885.1 - 0.46 10.3 2.8 0.44 10.4 0.5 2.1 2 1 0 2 2 2 0 SAP domain SDA1 PF05285.12 ORY49885.1 - 0.85 9.0 30.9 1.1 8.6 30.9 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 ORY49885.1 - 0.96 7.6 31.2 1.1 7.4 31.2 1.2 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 ORY49885.1 - 1.1 7.3 39.2 1.5 6.9 39.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 ORY49885.1 - 1.4 8.1 33.9 2 7.7 33.9 1.2 1 0 0 1 1 1 0 BUD22 GREB1 PF15782.5 ORY49885.1 - 3.8 4.5 6.9 4.4 4.3 6.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LAP1C PF05609.12 ORY49885.1 - 5.6 5.9 17.2 6.6 5.7 17.2 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Apt1 PF10351.9 ORY49885.1 - 6.7 5.4 9.7 8.5 5.1 9.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain tRNA-synt_2 PF00152.20 ORY49886.1 - 4.7e-92 308.4 0.1 9e-92 307.5 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 ORY49886.1 - 4.5e-10 39.4 0.0 1.2e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ras PF00071.22 ORY49887.1 - 6.1e-45 152.7 0.0 7.1e-45 152.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY49887.1 - 8.7e-17 61.5 0.0 1.2e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY49887.1 - 4.6e-05 22.9 0.0 6.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 ORY49887.1 - 0.012 15.3 0.1 1.1 9.0 0.1 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ANAPC4_WD40 PF12894.7 ORY49888.1 - 5.8e-11 42.5 0.1 9.7e-05 22.6 0.1 4.6 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_3 PF15911.5 ORY49888.1 - 3.3e-10 39.8 0.1 2.8e-09 36.8 0.0 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat Clathrin PF00637.20 ORY49888.1 - 6.5e-08 32.6 2.5 0.0026 17.6 0.2 5.1 4 1 1 5 5 5 2 Region in Clathrin and VPS WD40_like PF17005.5 ORY49888.1 - 3e-05 23.5 0.2 0.011 15.1 0.0 3.2 3 0 0 3 3 3 1 WD40-like domain TPR_7 PF13176.6 ORY49888.1 - 0.0024 17.8 4.8 16 5.8 0.0 5.8 6 1 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.32 ORY49888.1 - 0.0041 17.9 2.4 7.8 7.6 0.3 4.8 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 ORY49888.1 - 0.0087 15.1 1.9 0.063 12.3 0.1 2.8 4 0 0 4 4 4 1 Coatomer WD associated region TPR_14 PF13428.6 ORY49888.1 - 0.019 15.7 13.2 3.6 8.7 1.4 7.6 9 1 0 9 9 9 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY49888.1 - 0.088 13.1 18.3 3.3 8.1 0.3 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat SNAP PF14938.6 ORY49888.1 - 0.099 12.1 6.5 0.031 13.7 0.8 2.5 3 0 0 3 3 3 0 Soluble NSF attachment protein, SNAP MIT PF04212.18 ORY49888.1 - 0.18 11.9 9.2 5 7.3 0.0 4.1 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Mad3_BUB1_I PF08311.12 ORY49888.1 - 0.28 11.2 7.4 15 5.6 0.1 3.5 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 TPR_10 PF13374.6 ORY49888.1 - 0.6 10.1 7.4 5.9 6.9 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DZR PF12773.7 ORY49888.1 - 1.7 8.7 8.3 6.3 6.9 0.7 2.4 1 1 1 2 2 2 0 Double zinc ribbon zf-C2H2_4 PF13894.6 ORY49889.1 - 1.6e-07 31.5 31.4 0.0046 17.7 0.1 6.9 7 0 0 7 7 6 4 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY49889.1 - 2.2e-05 24.7 4.7 0.0025 18.2 0.7 6.8 7 0 0 7 7 7 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 ORY49889.1 - 0.0014 18.9 5.6 0.14 12.5 0.1 4.4 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf_ZIC PF18366.1 ORY49889.1 - 0.0063 16.6 4.3 2.4 8.4 0.2 3.5 3 0 0 3 3 3 2 Zic proteins zinc finger domain zf_UBZ PF18439.1 ORY49889.1 - 0.067 12.8 1.5 5.8 6.6 0.3 3.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 ORY49889.1 - 0.09 13.1 9.2 0.4 11.0 0.2 3.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 ORY49889.1 - 0.13 12.7 1.1 15 6.1 0.0 3.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type ZU5 PF00791.20 ORY49889.1 - 0.14 12.5 0.4 8.7 6.8 0.0 2.9 2 0 0 2 2 2 0 ZU5 domain DUF4729 PF15866.5 ORY49889.1 - 0.17 11.1 2.8 0.39 10.0 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4729) zf-H2C2_2 PF13465.6 ORY49889.1 - 0.25 11.9 0.1 0.25 11.9 0.1 5.7 7 0 0 7 7 5 0 Zinc-finger double domain ADK_lid PF05191.14 ORY49889.1 - 0.31 11.1 4.1 0.49 10.4 1.2 2.9 2 0 0 2 2 2 0 Adenylate kinase, active site lid YceD PF02620.17 ORY49889.1 - 1.1 9.3 3.5 5.4 7.2 0.2 3.3 4 0 0 4 4 4 0 Large ribosomal RNA subunit accumulation protein YceD zf-C2H2_2 PF12756.7 ORY49889.1 - 2.8 8.3 9.9 0.89 9.9 0.1 3.6 3 1 1 4 4 4 0 C2H2 type zinc-finger (2 copies) Hydrolase_6 PF13344.6 ORY49890.1 - 5.9e-26 90.5 0.0 1.3e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY49890.1 - 1.6e-15 56.9 0.0 5.5e-15 55.2 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 ORY49890.1 - 1.9e-06 28.3 0.0 6.6e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY49890.1 - 5.7e-06 26.5 0.0 0.0025 17.9 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Spherulin4 PF12138.8 ORY49890.1 - 0.18 11.4 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Spherulation-specific family 4 LSM PF01423.22 ORY49891.1 - 2.8e-18 65.3 0.2 3.9e-18 64.9 0.2 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 ORY49891.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Hfq protein Cation_efflux PF01545.21 ORY49892.1 - 2.8e-29 102.3 9.9 3.5e-29 102.0 9.9 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 ORY49892.1 - 0.0061 16.7 0.3 0.1 12.8 0.0 2.3 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter DUF2244 PF10003.9 ORY49892.1 - 0.063 12.9 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) ABC_cobalt PF09819.9 ORY49892.1 - 1.5 9.0 5.9 1.6 8.9 2.5 2.3 2 0 0 2 2 2 0 ABC-type cobalt transport system, permease component Ank_2 PF12796.7 ORY49893.1 - 7.4e-22 77.7 0.0 3.7e-11 43.5 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY49893.1 - 1.3e-13 51.1 0.9 0.00095 19.7 0.0 5.7 4 1 2 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY49893.1 - 3.3e-11 42.4 0.1 0.095 13.3 0.0 6.5 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.6 ORY49893.1 - 2e-08 34.3 1.4 0.004 17.4 0.0 5.5 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY49893.1 - 1.1e-06 28.8 1.5 1.2 9.8 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat ARD PF03079.14 ORY49894.1 - 2.5e-102 339.7 15.1 1.3e-51 174.9 3.4 2.1 2 0 0 2 2 2 2 ARD/ARD' family Cupin_2 PF07883.11 ORY49894.1 - 5.3e-18 64.5 0.0 1.2e-07 31.3 0.0 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 ORY49894.1 - 1.9e-12 47.2 0.0 5.7e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain LEDGF PF11467.8 ORY49894.1 - 0.0051 16.4 0.3 1.5 8.4 0.1 2.7 2 0 0 2 2 2 2 Lens epithelium-derived growth factor (LEDGF) Phage_term_smal PF05944.12 ORY49894.1 - 0.028 14.4 0.4 16 5.5 0.0 3.2 4 0 0 4 4 4 0 Phage small terminase subunit DUF1643 PF07799.12 ORY49894.1 - 0.053 13.7 0.3 3.4 7.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1643) DNA_Packaging PF11053.8 ORY49894.1 - 0.12 12.2 0.1 21 4.9 0.0 2.5 2 0 0 2 2 2 0 Terminase DNA packaging enzyme DUF2884 PF11101.8 ORY49894.1 - 0.89 9.0 5.1 8.7 5.8 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) Phage_Gp17 PF17549.2 ORY49894.1 - 1.5 8.9 11.7 4.5 7.3 1.5 3.2 3 2 0 3 3 3 0 Gene Product 17 TPT PF03151.16 ORY49895.1 - 1.7e-23 83.4 25.7 2e-23 83.2 25.7 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORY49895.1 - 0.00023 21.3 38.5 0.013 15.6 15.0 3.1 2 1 0 2 2 2 2 EamA-like transporter family ApoL PF05461.11 ORY49895.1 - 0.011 15.0 3.6 0.022 14.1 3.6 1.4 1 0 0 1 1 1 0 Apolipoprotein L TMEM234 PF10639.9 ORY49895.1 - 0.14 12.2 11.9 0.17 11.9 3.7 2.5 2 0 0 2 2 2 0 Putative transmembrane family 234 PUNUT PF16913.5 ORY49895.1 - 0.3 10.3 23.3 7.2 5.7 23.3 2.6 1 1 0 1 1 1 0 Purine nucleobase transmembrane transport Asp PF00026.23 ORY49896.1 - 3e-31 109.0 2.7 4e-31 108.6 2.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.6 ORY49896.1 - 1e-05 26.0 0.8 0.0019 18.8 0.7 3.3 2 1 0 2 2 2 1 Aspartyl protease TAXi_N PF14543.6 ORY49896.1 - 0.00016 22.0 7.5 0.00024 21.4 3.9 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.6 ORY49896.1 - 0.00051 20.5 0.2 0.4 11.3 0.1 3.3 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease MOZ_SAS PF01853.18 ORY49896.1 - 0.0091 15.7 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family Ank_2 PF12796.7 ORY49897.1 - 0.0037 17.8 0.0 0.031 14.8 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) F-box PF00646.33 ORY49897.1 - 0.034 14.0 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 F-box domain Tyrosinase PF00264.20 ORY49898.1 - 1.6e-23 84.2 7.2 4.1e-21 76.3 7.2 2.4 1 1 0 1 1 1 1 Common central domain of tyrosinase CAP_N PF01213.19 ORY49898.1 - 0.26 10.7 1.8 0.38 10.2 1.8 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal F-box PF00646.33 ORY49899.1 - 0.015 15.2 0.1 0.033 14.1 0.1 1.6 1 0 0 1 1 1 0 F-box domain Helicase_C PF00271.31 ORY49900.1 - 4.6e-10 39.8 0.0 7.4e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Reductase_C PF14759.6 ORY49900.1 - 0.027 15.0 0.0 0.062 13.9 0.0 1.8 1 1 0 1 1 1 0 Reductase C-terminal Fer4_22 PF17179.4 ORY49901.1 - 0.063 14.1 0.4 0.42 11.5 0.0 2.3 3 0 0 3 3 3 0 4Fe-4S dicluster domain zf-C2H2 PF00096.26 ORY49902.1 - 0.028 14.9 2.2 0.028 14.9 2.2 2.9 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY49902.1 - 0.92 10.1 5.4 17 6.0 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger double domain EF-hand_7 PF13499.6 ORY49904.1 - 1.1e-14 54.6 6.2 1.9e-08 34.6 1.4 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 ORY49904.1 - 1.1e-11 43.4 4.1 0.00029 20.2 0.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 ORY49904.1 - 2.8e-11 42.4 5.4 0.0016 18.2 0.4 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 ORY49904.1 - 0.00015 21.5 7.5 0.0032 17.3 1.9 3.7 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 ORY49904.1 - 0.00047 19.5 0.2 0.00047 19.5 0.2 2.8 4 0 0 4 4 4 1 EF hand EF-hand_4 PF12763.7 ORY49904.1 - 0.0022 17.9 1.8 0.059 13.3 0.3 2.6 1 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Lipase_GDSL_2 PF13472.6 ORY49905.1 - 0.0027 18.1 0.0 0.003 18.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family LRR_4 PF12799.7 ORY49906.1 - 3.1e-25 87.8 49.8 2.6e-07 30.8 1.4 5.3 1 1 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY49906.1 - 3.2e-25 87.7 26.3 5.3e-10 38.9 3.8 4.0 2 2 3 5 5 5 5 Leucine rich repeat LRR_1 PF00560.33 ORY49906.1 - 5.2e-08 32.4 21.7 0.025 15.1 0.3 7.5 8 1 0 8 8 8 3 Leucine Rich Repeat LRR_6 PF13516.6 ORY49906.1 - 4.9e-06 26.2 24.4 0.38 10.9 0.3 6.7 8 0 0 8 8 8 4 Leucine Rich repeat LRR_5 PF13306.6 ORY49906.1 - 5.1e-05 23.2 0.3 0.0082 16.1 0.1 2.3 1 1 1 3 3 3 1 BspA type Leucine rich repeat region (6 copies) LRR_9 PF14580.6 ORY49906.1 - 0.00023 20.7 9.8 0.086 12.3 0.9 3.1 2 1 2 4 4 4 3 Leucine-rich repeat LRR_2 PF07723.13 ORY49906.1 - 0.058 14.1 1.3 28 5.6 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich Repeat Phage_r1t_holin PF16945.5 ORY49906.1 - 0.062 13.5 0.2 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 Putative lactococcus lactis phage r1t holin Lactamase_B PF00753.27 ORY49907.1 - 5.7e-19 68.9 3.9 9.1e-19 68.2 3.9 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily BLACT_WH PF17778.1 ORY49907.1 - 4.7e-15 55.3 0.0 1.3e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_2 PF12706.7 ORY49907.1 - 2.5e-07 30.4 0.2 3.6e-07 29.9 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORY49907.1 - 0.0042 17.0 0.1 0.0063 16.4 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DASH_Dad1 PF08649.10 ORY49908.1 - 0.023 14.9 0.2 0.15 12.3 0.2 2.4 1 1 0 1 1 1 0 DASH complex subunit Dad1 HTH_34 PF13601.6 ORY49908.1 - 0.094 12.9 0.2 0.26 11.5 0.2 1.8 1 0 0 1 1 1 0 Winged helix DNA-binding domain DED PF01335.21 ORY49908.1 - 0.15 12.3 2.2 0.22 11.8 0.5 2.2 3 0 0 3 3 3 0 Death effector domain Rx_N PF18052.1 ORY49908.1 - 0.31 11.4 1.7 12 6.2 0.3 2.6 2 0 0 2 2 2 0 Rx N-terminal domain IL13 PF03487.13 ORY49908.1 - 0.32 10.8 1.5 0.6 9.9 0.2 2.1 2 0 0 2 2 2 0 Interleukin-13 Takusan PF04822.13 ORY49908.1 - 0.59 10.1 5.9 7.3 6.6 0.7 3.3 3 0 0 3 3 3 0 Takusan Prefoldin PF02996.17 ORY49908.1 - 1.1 9.2 4.7 0.58 10.1 0.3 2.5 3 0 0 3 3 3 0 Prefoldin subunit IQ PF00612.27 ORY49909.1 - 0.0079 15.9 9.2 0.09 12.6 1.8 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif PH PF00169.29 ORY49910.1 - 3.7e-39 133.5 3.9 1.9e-20 73.3 0.2 3.0 3 0 0 3 3 3 2 PH domain PH_11 PF15413.6 ORY49910.1 - 1.4e-14 54.3 16.2 1.5e-06 28.5 3.5 4.1 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.6 ORY49910.1 - 1.1e-10 41.6 2.9 5.7e-05 23.3 0.2 2.3 2 0 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 ORY49910.1 - 1.9e-08 34.3 3.1 0.00061 19.9 0.3 2.4 2 0 0 2 2 2 2 PH domain PH_9 PF15410.6 ORY49910.1 - 8.4e-06 26.2 7.2 0.0081 16.5 0.9 4.0 2 2 0 2 2 2 2 Pleckstrin homology domain PH_13 PF16652.5 ORY49910.1 - 0.0041 16.9 0.1 0.11 12.3 0.1 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH_4 PF15404.6 ORY49910.1 - 0.078 12.8 0.6 8.9 6.1 0.1 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain HflK_N PF12221.8 ORY49911.1 - 0.024 14.6 0.1 0.067 13.2 0.1 1.7 1 0 0 1 1 1 0 Bacterial membrane protein N terminal CCDC144C PF14915.6 ORY49911.1 - 0.043 12.9 8.8 0.016 14.3 4.9 2.0 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region DUF3537 PF12056.8 ORY49911.1 - 0.49 9.2 1.1 0.95 8.2 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) PPR PF01535.20 ORY49912.1 - 2.2e-10 40.1 6.8 3.1 8.2 0.0 8.7 9 0 0 9 9 9 3 PPR repeat PPR_2 PF13041.6 ORY49912.1 - 2e-09 37.5 4.2 0.015 15.5 0.1 7.3 7 0 0 7 7 7 1 PPR repeat family PPR_3 PF13812.6 ORY49912.1 - 1.8e-05 24.7 0.1 0.051 13.7 0.0 3.7 4 0 0 4 4 4 2 Pentatricopeptide repeat domain TPR_19 PF14559.6 ORY49912.1 - 7.6e-05 23.1 0.4 1.6 9.3 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat PPR_long PF17177.4 ORY49912.1 - 0.00014 21.3 0.2 0.064 12.6 0.0 4.4 4 1 1 5 5 5 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 ORY49912.1 - 0.00026 20.6 0.0 1.4 8.7 0.0 4.2 5 0 0 5 5 5 2 PPR repeat SOG2 PF10428.9 ORY49912.1 - 0.0076 15.5 4.9 0.019 14.2 4.5 1.7 2 0 0 2 2 2 1 RAM signalling pathway protein 4HB_MCP_1 PF12729.7 ORY49912.1 - 0.02 14.4 0.1 3.6 7.1 0.0 2.9 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction TPR_12 PF13424.6 ORY49912.1 - 0.064 13.6 0.9 72 3.8 0.0 5.3 5 1 0 5 5 5 0 Tetratricopeptide repeat CAP_N PF01213.19 ORY49912.1 - 1.5 8.2 6.0 2.9 7.3 6.0 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RVT_3 PF13456.6 ORY49913.1 - 2.7e-07 30.4 0.0 4.6e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like Zn_clus PF00172.18 ORY49913.1 - 0.0011 19.0 12.1 0.0033 17.5 12.1 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.29 ORY49914.1 - 2.3e-34 118.6 0.0 3.7e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY49914.1 - 9.6e-07 28.5 0.1 2e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 ORY49914.1 - 7.7e-06 26.0 0.0 1.7e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 ORY49914.1 - 0.00012 21.9 0.0 0.00028 20.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY49914.1 - 0.00015 22.2 0.5 0.0078 16.6 0.2 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY49914.1 - 0.00037 20.8 0.2 0.017 15.4 0.1 2.5 1 1 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 ORY49914.1 - 0.0009 19.4 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 ORY49914.1 - 0.0012 18.6 0.0 0.0022 17.8 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 ORY49914.1 - 0.0014 18.7 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ORY49914.1 - 0.0017 17.9 0.1 0.0045 16.5 0.1 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 ORY49914.1 - 0.0047 17.1 0.0 0.0099 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ORY49914.1 - 0.005 16.2 0.0 0.0084 15.5 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 ORY49914.1 - 0.01 15.2 0.0 2.6 7.4 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein AAA_18 PF13238.6 ORY49914.1 - 0.013 16.1 0.0 0.025 15.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 ORY49914.1 - 0.025 14.5 0.0 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 ORY49914.1 - 0.025 14.3 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 ORY49914.1 - 0.025 14.7 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 ORY49914.1 - 0.036 13.3 0.0 0.067 12.4 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain RNA_helicase PF00910.22 ORY49914.1 - 0.042 14.2 0.0 0.072 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 ORY49914.1 - 0.046 13.4 0.0 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 ORY49914.1 - 0.047 14.2 0.0 0.14 12.7 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 ORY49914.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 ORY49914.1 - 0.14 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 ORY49914.1 - 0.21 11.0 0.1 0.41 10.1 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Mito_carr PF00153.27 ORY49915.1 - 1.1e-54 182.3 0.3 5.3e-19 67.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein baeRF_family5 PF18846.1 ORY49915.1 - 0.031 14.5 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 5 GMC_oxred_N PF00732.19 ORY49916.1 - 2.6e-60 204.3 0.0 3.8e-60 203.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 ORY49916.1 - 4.7e-31 108.3 0.0 8.9e-31 107.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 ORY49916.1 - 0.00081 18.6 0.0 0.33 10.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 ORY49916.1 - 0.0009 18.4 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 ORY49916.1 - 0.0015 17.8 0.0 0.0034 16.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 ORY49916.1 - 0.0023 18.1 0.0 0.0055 16.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 ORY49916.1 - 0.01 15.4 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase CCB1 PF12046.8 ORY49916.1 - 0.12 11.8 0.1 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B FAD_binding_3 PF01494.19 ORY49917.1 - 2.2e-22 79.8 0.0 3.1e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 ORY49917.1 - 7.3e-05 22.1 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 ORY49917.1 - 0.0001 21.7 0.0 0.0012 18.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY49917.1 - 0.00017 21.8 0.2 0.00038 20.6 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORY49917.1 - 0.00018 20.7 0.1 0.00032 19.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 ORY49917.1 - 0.0004 20.1 0.4 0.0012 18.5 0.3 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ORY49917.1 - 0.0019 17.3 0.0 0.015 14.3 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 ORY49917.1 - 0.0024 16.8 0.1 0.43 9.4 0.1 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.27 ORY49917.1 - 0.0065 17.0 0.1 0.27 11.8 0.2 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 ORY49917.1 - 0.03 13.4 0.0 0.095 11.7 0.0 1.8 1 1 0 1 1 1 0 Squalene epoxidase NAD_binding_9 PF13454.6 ORY49917.1 - 0.046 13.7 0.0 0.11 12.4 0.0 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 ORY49917.1 - 0.17 10.6 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein K_oxygenase PF13434.6 ORY49917.1 - 0.2 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pkr1 PF08636.10 ORY49919.1 - 4.6e-22 77.9 6.3 6.9e-22 77.4 6.3 1.3 1 0 0 1 1 1 1 ER protein Pkr1 Shisa PF13908.6 ORY49919.1 - 0.12 12.6 0.4 0.27 11.4 0.0 1.7 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Arf PF00025.21 ORY49920.1 - 1.1e-09 37.9 1.0 2.5e-06 27.1 0.0 2.9 1 1 1 2 2 2 2 ADP-ribosylation factor family TCL1_MTCP1 PF01840.17 ORY49920.1 - 0.071 12.8 2.2 0.22 11.2 2.2 1.8 1 0 0 1 1 1 0 TCL1/MTCP1 family MMR_HSR1 PF01926.23 ORY49920.1 - 0.072 13.2 0.5 0.2 11.8 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase PAT1 PF09770.9 ORY49921.1 - 5.4e-63 213.6 68.1 3.3e-39 134.9 0.0 6.0 5 1 1 6 6 6 5 Topoisomerase II-associated protein PAT1 LRR_6 PF13516.6 ORY49922.1 - 0.0023 17.9 3.8 3.3 8.0 0.0 4.5 5 0 0 5 5 5 2 Leucine Rich repeat Whi5 PF08528.11 ORY49923.1 - 2e-08 33.7 0.1 3e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 Whi5 like Phage_GP20 PF06810.11 ORY49924.1 - 0.0011 18.7 5.5 0.0014 18.5 0.2 2.2 2 0 0 2 2 2 1 Phage minor structural protein GP20 GrpE PF01025.19 ORY49924.1 - 0.013 15.1 6.9 0.02 14.6 2.0 2.2 2 0 0 2 2 2 0 GrpE UPF0242 PF06785.11 ORY49924.1 - 0.021 15.0 0.5 0.021 15.0 0.5 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Tho2 PF11262.8 ORY49924.1 - 0.18 11.0 3.2 0.23 10.6 0.7 1.9 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 PAS PF00989.25 ORY49924.1 - 0.34 10.9 1.3 0.69 9.9 0.1 2.0 2 0 0 2 2 2 0 PAS fold Filament PF00038.21 ORY49924.1 - 1.1 8.8 10.3 0.27 10.8 1.3 2.1 2 0 0 2 2 2 0 Intermediate filament protein APG6_N PF17675.1 ORY49924.1 - 2.5 8.6 10.9 3.4 8.2 1.1 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region GAS PF13851.6 ORY49924.1 - 2.7 7.3 12.0 4.6 6.5 2.1 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spc24 PF08286.11 ORY49924.1 - 7 6.9 9.0 1 9.7 1.7 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4407 PF14362.6 ORY49924.1 - 8.4 5.7 8.2 39 3.5 8.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TatD_DNase PF01026.21 ORY49925.1 - 5.3e-29 101.4 0.0 7e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase RNase_T PF00929.24 ORY49925.1 - 1.7e-09 38.5 0.0 3.2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Exonuclease DUF885 PF05960.11 ORY49926.1 - 6e-51 174.7 0.0 5.4e-28 98.9 0.1 2.2 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF885) GAS PF13851.6 ORY49927.1 - 0.011 15.2 0.2 0.015 14.6 0.2 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding RNase_T PF00929.24 ORY49928.1 - 1.6e-10 41.8 0.0 2.5e-09 37.9 0.0 2.0 1 1 0 2 2 2 1 Exonuclease F-box-like PF12937.7 ORY49929.1 - 6.7e-09 35.5 0.0 1.3e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY49929.1 - 3.9e-06 26.6 0.0 1.4e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 ORY49929.1 - 0.039 13.9 0.0 0.094 12.6 0.0 1.7 1 0 0 1 1 1 0 F-box FSH1 PF03959.13 ORY49930.1 - 2.2e-23 83.0 0.0 3.8e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) RWD PF05773.22 ORY49930.1 - 1.4e-12 47.9 0.0 2.7e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 RWD domain MMR_HSR1_C PF08438.10 ORY49930.1 - 3.9e-10 40.3 0.0 9.5e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 ORY49930.1 - 2.8e-07 30.6 0.0 9.5e-07 28.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY49930.1 - 0.021 14.3 0.0 0.084 12.4 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B Peptidase_C48 PF02902.19 ORY49931.1 - 5.2e-12 46.1 2.5 1.3e-09 38.2 0.1 2.3 1 1 1 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Kinesin PF00225.23 ORY49932.1 - 6.1e-83 278.5 2.5 8e-83 278.1 0.0 2.3 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ORY49932.1 - 1.8e-25 89.6 1.4 3.8e-25 88.6 0.0 2.2 2 1 0 2 2 2 1 Microtubule binding SepF PF04472.12 ORY49932.1 - 0.066 13.5 0.7 0.2 12.0 0.7 1.8 1 0 0 1 1 1 0 Cell division protein SepF AAA_22 PF13401.6 ORY49932.1 - 0.12 12.7 3.9 0.25 11.6 0.0 3.1 2 1 0 3 3 3 0 AAA domain Use1 PF09753.9 ORY49932.1 - 0.51 10.0 34.9 34 4.0 28.7 2.2 1 1 1 2 2 2 0 Membrane fusion protein Use1 Ribosomal_L35Ae PF01247.18 ORY49933.1 - 3.3e-44 149.0 0.4 3.8e-44 148.8 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 ORY49933.1 - 0.026 14.7 0.1 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 RimM N-terminal domain DUF2080 PF09853.9 ORY49933.1 - 0.26 11.1 1.2 2.1 8.1 0.1 2.6 1 1 2 3 3 3 0 Putative transposon-encoded protein (DUF2080) DUF5122 PF17164.4 ORY49934.1 - 0.2 12.0 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5122) beta-propeller dCache_1 PF02743.18 ORY49935.1 - 3.9e-13 49.8 3.9 2.3e-12 47.2 3.2 2.0 1 1 1 2 2 2 1 Cache domain ATP-synt_I PF03899.15 ORY49935.1 - 1.8 9.0 7.7 0.81 10.1 2.5 2.3 2 0 0 2 2 2 0 ATP synthase I chain dCache_1 PF02743.18 ORY49936.1 - 7.5e-13 48.8 0.2 7.5e-13 48.8 0.2 2.7 2 1 1 3 3 3 1 Cache domain TPR_12 PF13424.6 ORY49936.1 - 4.2e-12 46.2 1.7 1.2e-06 28.6 0.6 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat dCache_2 PF08269.11 ORY49936.1 - 0.0004 19.7 0.2 0.001 18.3 0.0 1.7 2 0 0 2 2 2 1 Cache domain TPR_10 PF13374.6 ORY49936.1 - 0.00075 19.3 2.9 0.053 13.4 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY49936.1 - 0.0011 18.9 0.0 1.3 9.3 0.0 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat Cache_3-Cache_2 PF17201.4 ORY49936.1 - 0.024 13.9 0.0 0.051 12.8 0.0 1.5 1 0 0 1 1 1 0 Cache 3/Cache 2 fusion domain TPR_2 PF07719.17 ORY49936.1 - 0.073 13.2 0.6 1.3 9.3 0.0 3.1 2 1 0 2 2 2 0 Tetratricopeptide repeat Clc-like PF07062.12 ORY49936.1 - 0.08 12.4 0.2 0.13 11.8 0.2 1.2 1 0 0 1 1 1 0 Clc-like TPR_8 PF13181.6 ORY49936.1 - 0.081 13.2 0.4 3.1 8.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY49936.1 - 0.21 11.5 0.1 0.21 11.5 0.1 3.9 5 1 0 5 5 5 0 Tetratricopeptide repeat FIVAR PF07554.13 ORY49936.1 - 0.56 11.0 2.6 1 10.1 0.3 2.7 3 0 0 3 3 3 0 FIVAR domain TPR_12 PF13424.6 ORY49937.1 - 6.5e-14 52.0 1.3 1.8e-05 24.9 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat VWA PF00092.28 ORY49937.1 - 5.9e-13 49.4 0.2 1.5e-12 48.1 0.2 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain TPR_7 PF13176.6 ORY49937.1 - 2.2e-10 39.8 1.6 0.051 13.6 0.1 4.0 5 0 0 5 5 3 3 Tetratricopeptide repeat VWA_2 PF13519.6 ORY49937.1 - 2.2e-09 37.9 0.1 1.5e-08 35.2 0.0 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain TPR_10 PF13374.6 ORY49937.1 - 2e-06 27.5 2.9 0.0099 15.7 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY49937.1 - 2.3e-06 27.3 3.0 0.12 12.6 0.3 4.3 4 1 0 4 4 3 2 Tetratricopeptide repeat VWA_3 PF13768.6 ORY49937.1 - 4.4e-06 26.7 0.0 8.2e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain TPR_1 PF00515.28 ORY49937.1 - 2.1e-05 24.1 10.4 0.052 13.4 0.5 4.9 5 1 0 5 5 5 2 Tetratricopeptide repeat VWA_CoxE PF05762.14 ORY49937.1 - 0.00023 20.6 0.0 0.00038 19.9 0.0 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein TPR_11 PF13414.6 ORY49937.1 - 0.0011 18.7 3.4 0.69 9.7 0.1 4.3 4 1 1 5 5 5 1 TPR repeat TPR_8 PF13181.6 ORY49937.1 - 0.0021 18.1 5.2 1.5 9.2 0.2 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat DUF2201 PF09967.9 ORY49937.1 - 0.0063 16.6 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 VWA-like domain (DUF2201) MIT PF04212.18 ORY49937.1 - 0.025 14.6 0.0 6 7.0 0.0 3.0 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_MalT PF17874.1 ORY49937.1 - 0.057 12.8 0.0 3.2 7.0 0.0 2.2 2 0 0 2 2 2 0 MalT-like TPR region vWA-TerF-like PF10138.9 ORY49937.1 - 0.062 13.4 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 vWA found in TerF C terminus TPR_16 PF13432.6 ORY49937.1 - 0.085 13.5 0.1 43 4.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat dCache_1 PF02743.18 ORY49938.1 - 1.3e-09 38.2 0.0 2.1e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Cache domain dCache_2 PF08269.11 ORY49938.1 - 0.058 12.6 0.0 0.082 12.1 0.0 1.1 1 0 0 1 1 1 0 Cache domain CsgE PF10627.9 ORY49939.1 - 0.12 12.7 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Curli assembly protein CsgE cNMP_binding PF00027.29 ORY49941.1 - 5.6e-20 71.2 0.0 1.6e-19 69.8 0.1 1.8 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain TMEM234 PF10639.9 ORY49944.1 - 9.5e-23 80.5 0.1 2e-22 79.4 0.1 1.5 1 1 0 1 1 1 1 Putative transmembrane family 234 EamA PF00892.20 ORY49944.1 - 0.0013 18.9 0.6 0.46 10.7 0.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family Ion_trans PF00520.31 ORY49945.1 - 4.3e-30 104.7 26.8 5.9e-30 104.3 26.8 1.1 1 0 0 1 1 1 1 Ion transport protein Pkinase_fungal PF17667.1 ORY49945.1 - 0.0024 16.7 0.3 0.0046 15.8 0.3 1.4 1 0 0 1 1 1 1 Fungal protein kinase Aldedh PF00171.22 ORY49946.1 - 7.6e-88 295.0 0.0 9e-88 294.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 ORY49946.1 - 0.0081 15.6 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) Cse1 PF08506.10 ORY49947.1 - 1.1e-145 485.2 7.7 1.8e-145 484.4 4.6 2.3 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 ORY49947.1 - 8.9e-126 419.9 1.1 8.9e-126 419.9 1.1 3.2 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 ORY49947.1 - 1e-11 44.5 0.0 9.3e-11 41.5 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Phyto_Pns9_10 PF05878.11 ORY49947.1 - 0.035 13.2 0.0 0.07 12.3 0.0 1.5 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Xpo1 PF08389.12 ORY49947.1 - 5.4 7.1 10.9 0.24 11.5 0.1 4.2 6 1 0 6 6 6 0 Exportin 1-like protein Peptidase_C54 PF03416.19 ORY49948.1 - 3.3e-102 341.6 0.0 3.9e-102 341.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase family C54 Na_Ca_ex PF01699.24 ORY49949.1 - 1.9e-35 122.0 49.7 2e-18 66.8 20.8 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Cyto_heme_lyase PF01265.17 ORY49950.1 - 3.5e-73 246.8 1.3 3.1e-72 243.6 1.3 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase SET PF00856.28 ORY49951.1 - 7.6e-21 75.2 0.5 4e-20 72.9 0.5 1.8 1 1 0 1 1 1 1 SET domain DUF4176 PF13780.6 ORY49951.1 - 0.14 12.2 0.4 0.47 10.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4176) TP6A_N PF04406.14 ORY49952.1 - 1.5e-19 69.7 0.1 2.8e-19 68.9 0.1 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Methyltransf_16 PF10294.9 ORY49954.1 - 6.6e-22 78.1 0.1 9.8e-22 77.5 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 ORY49954.1 - 0.006 16.4 0.0 0.0077 16.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain QIL1 PF15884.5 ORY49955.1 - 0.0013 19.3 2.2 14 6.4 0.0 4.8 5 0 0 5 5 5 1 MICOS complex subunit MIC13, QIL1 DUF2333 PF10095.9 ORY49955.1 - 0.032 13.2 0.0 0.072 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) GCSF PF16647.5 ORY49955.1 - 0.081 12.8 0.6 1.1 9.0 0.0 2.8 3 0 0 3 3 3 0 Granulocyte colony-stimulating factor Methyltransf_PK PF05891.12 ORY49955.1 - 0.09 12.3 0.1 1.1 8.7 0.0 2.3 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase DUF3052 PF11253.8 ORY49955.1 - 0.11 12.4 2.2 0.31 11.0 2.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) Sec8_exocyst PF04048.14 ORY49955.1 - 0.13 12.2 11.1 2 8.3 0.0 4.6 4 1 1 5 5 5 0 Sec8 exocyst complex component specific domain MutS_III PF05192.18 ORY49955.1 - 0.15 12.2 10.3 0.082 13.1 4.0 2.5 2 1 0 2 2 2 0 MutS domain III SWIRM-assoc_1 PF16495.5 ORY49955.1 - 0.3 11.0 3.2 0.25 11.3 0.2 2.3 2 1 0 2 2 2 0 SWIRM-associated region 1 Prominin PF05478.11 ORY49955.1 - 0.77 7.6 8.3 1.8 6.4 8.3 1.6 1 1 0 1 1 1 0 Prominin GvpL_GvpF PF06386.11 ORY49955.1 - 9.1 6.1 10.7 1.1 9.1 3.5 2.4 1 1 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF TPR_MLP1_2 PF07926.12 ORY49957.1 - 0.001 19.1 1.9 0.001 19.1 1.9 2.0 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein DUF4618 PF15397.6 ORY49957.1 - 0.0011 18.4 6.0 0.0011 18.4 6.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4618) CENP-F_leu_zip PF10473.9 ORY49957.1 - 0.026 14.5 13.9 0.11 12.5 10.0 2.8 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HlyD_2 PF12700.7 ORY49957.1 - 0.096 11.4 7.9 0.13 10.9 7.9 1.2 1 0 0 1 1 1 0 HlyD family secretion protein V-SNARE PF05008.15 ORY49957.1 - 0.3 11.5 5.6 2.2 8.7 0.6 2.5 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus SlyX PF04102.12 ORY49957.1 - 0.41 11.3 4.7 11 6.7 1.7 2.8 3 0 0 3 3 3 0 SlyX V_ATPase_I PF01496.19 ORY49957.1 - 0.45 8.4 3.6 0.51 8.2 3.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc7 PF08317.11 ORY49957.1 - 0.51 9.2 9.8 0.68 8.8 9.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein peroxidase PF00141.23 ORY49958.1 - 6.4e-29 101.3 0.0 1.2e-28 100.4 0.0 1.4 1 0 0 1 1 1 1 Peroxidase Allantoicase PF03561.15 ORY49959.1 - 2.8e-85 283.5 0.0 5.2e-45 153.0 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_lyase PF04115.12 ORY49960.1 - 1.1e-55 188.3 0.0 1.2e-55 188.2 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase DUF1624 PF07786.12 ORY49961.1 - 1.4e-10 41.1 3.5 1.7e-10 40.8 3.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1624) DUF5009 PF16401.5 ORY49961.1 - 1.3e-06 28.2 4.1 8.5e-05 22.2 4.1 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF5009) Pkinase PF00069.25 ORY49962.1 - 2.1e-72 243.7 0.0 2.8e-72 243.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY49962.1 - 7.4e-36 123.7 0.0 1.1e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY49962.1 - 4.7e-10 39.3 0.0 6.9e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY49962.1 - 0.00065 19.1 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY49962.1 - 0.0013 18.7 0.4 0.0031 17.5 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 ORY49962.1 - 0.012 15.2 0.1 0.032 13.8 0.1 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 ORY49962.1 - 0.013 14.5 0.1 0.023 13.7 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 ORY49962.1 - 0.068 12.2 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PAP2 PF01569.21 ORY49963.1 - 7.6e-13 48.4 6.4 1e-12 48.0 6.4 1.1 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 ORY49963.1 - 0.031 14.4 2.0 2.4 8.3 0.4 2.2 1 1 1 2 2 2 0 Divergent PAP2 family DUF3902 PF13042.6 ORY49963.1 - 0.074 12.6 3.2 0.1 12.2 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3902) Polysacc_synt_C PF14667.6 ORY49963.1 - 0.13 12.4 5.2 0.16 12.0 5.2 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain ABC_tran PF00005.27 ORY49964.1 - 2.6e-26 92.8 0.0 4.6e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 ORY49964.1 - 3e-09 36.6 11.8 6.3e-09 35.6 11.8 1.5 1 0 0 1 1 1 1 ABC-2 type transporter RsgA_GTPase PF03193.16 ORY49964.1 - 5.7e-05 23.1 0.1 0.0001 22.3 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase ATPase PF06745.13 ORY49964.1 - 0.0065 15.8 0.0 0.029 13.7 0.0 1.9 2 0 0 2 2 2 1 KaiC AAA_29 PF13555.6 ORY49964.1 - 0.0081 15.9 0.4 0.02 14.6 0.4 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 ORY49964.1 - 0.015 15.0 0.4 0.029 14.1 0.4 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ORY49964.1 - 0.016 15.3 0.2 0.044 13.9 0.2 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY49964.1 - 0.019 15.4 0.0 0.03 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ORY49964.1 - 0.025 14.8 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY49964.1 - 0.026 14.9 0.0 0.049 14.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 ORY49964.1 - 0.028 14.0 1.0 0.037 13.6 0.1 1.6 2 0 0 2 2 1 0 AAA domain Rad51 PF08423.11 ORY49964.1 - 0.035 13.4 0.1 0.058 12.6 0.1 1.3 1 0 0 1 1 1 0 Rad51 AAA_21 PF13304.6 ORY49964.1 - 0.043 13.6 0.3 6.4 6.5 0.1 2.2 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 ORY49964.1 - 0.047 13.4 0.3 0.13 12.0 0.3 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ORY49964.1 - 0.069 13.6 0.2 0.069 13.6 0.2 2.1 1 1 1 2 2 2 0 AAA domain RIFIN PF02009.16 ORY49964.1 - 0.086 12.7 0.3 0.17 11.8 0.3 1.4 1 0 0 1 1 1 0 Rifin SMC_N PF02463.19 ORY49964.1 - 0.11 11.9 0.4 0.61 9.5 0.4 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 ORY49964.1 - 0.22 11.1 0.8 0.82 9.2 0.2 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain START PF01852.19 ORY49965.1 - 4.4e-16 58.9 0.0 5.3e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 START domain PIN_6 PF17146.4 ORY49965.1 - 0.019 15.4 0.0 0.035 14.6 0.0 1.4 1 0 0 1 1 1 0 PIN domain of ribonuclease DUF4690 PF15756.5 ORY49966.1 - 0.002 18.7 0.8 0.032 14.8 0.1 2.4 2 0 0 2 2 2 1 Small Novel Rich in Cartilage CBM_5_12 PF02839.14 ORY49966.1 - 0.0028 18.2 0.1 0.0028 18.2 0.1 3.1 3 0 0 3 3 3 1 Carbohydrate binding domain CBM_5_12_2 PF14600.6 ORY49966.1 - 0.052 13.5 1.1 0.094 12.7 1.1 1.4 1 0 0 1 1 1 0 Cellulose-binding domain Phage_holin_3_6 PF07332.11 ORY49966.1 - 0.15 12.1 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III HeH PF12949.7 ORY49967.1 - 0.042 13.6 0.1 0.093 12.5 0.1 1.6 1 0 0 1 1 1 0 HeH/LEM domain SNF2_N PF00176.23 ORY49969.1 - 1.7e-25 89.5 0.0 5.9e-25 87.7 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 ORY49969.1 - 2.9e-09 36.7 4.9 5.5e-09 35.8 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY49969.1 - 1e-08 35.0 3.8 1.9e-08 34.1 3.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 ORY49969.1 - 6.8e-08 32.7 6.6 1.7e-07 31.4 6.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY49969.1 - 1.1e-06 28.4 6.0 3.1e-06 26.9 6.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 ORY49969.1 - 1.3e-06 28.5 0.0 1.3e-06 28.5 0.0 2.6 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit zf-RING_UBOX PF13445.6 ORY49969.1 - 4.9e-06 26.5 2.6 1.3e-05 25.1 2.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY49969.1 - 6.2e-06 26.0 4.2 1.4e-05 24.9 4.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.31 ORY49969.1 - 0.00012 22.4 0.0 0.12 12.7 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.6 ORY49969.1 - 0.00042 20.1 8.5 0.0018 18.1 8.4 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 ORY49969.1 - 0.0019 17.9 1.3 0.0065 16.2 1.3 2.0 1 0 0 1 1 1 1 RING-like zinc finger FapA PF03961.13 ORY49969.1 - 0.0061 15.2 3.5 0.013 14.1 3.5 1.5 1 0 0 1 1 1 1 Flagellar Assembly Protein A TetR_N PF00440.23 ORY49969.1 - 0.0082 15.9 0.1 5 7.0 0.0 2.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, tetR family zf-RING_6 PF14835.6 ORY49969.1 - 0.13 12.2 1.7 0.33 10.8 1.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DZR PF12773.7 ORY49969.1 - 0.19 11.8 4.6 0.38 10.8 4.6 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 ORY49969.1 - 0.28 11.4 7.8 0.045 13.9 3.6 1.9 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 ORY49969.1 - 0.41 11.0 5.9 1 9.7 5.9 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 ORY49969.1 - 0.45 10.3 7.3 1.1 9.1 7.3 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PBP1_TM PF14812.6 ORY49969.1 - 2.1 8.7 13.7 0.47 10.9 6.0 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-P11 PF03854.14 ORY49969.1 - 4.3 7.1 8.9 0.53 10.0 4.4 1.8 2 0 0 2 2 2 0 P-11 zinc finger zf-MYND PF01753.18 ORY49970.1 - 1.9e-07 31.0 10.9 1.9e-07 31.0 10.9 1.9 2 0 0 2 2 2 1 MYND finger gag-asp_proteas PF13975.6 ORY49970.1 - 0.0016 19.0 0.0 3.4 8.3 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 ORY49970.1 - 0.0032 18.1 0.1 2.6 8.7 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease zf-C6H2 PF15801.5 ORY49970.1 - 0.009 16.3 8.9 0.009 16.3 8.9 2.2 3 0 0 3 3 3 1 zf-MYND-like zinc finger, mRNA-binding RVP_2 PF08284.11 ORY49970.1 - 0.013 15.2 0.1 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 Retroviral aspartyl protease dCache_1 PF02743.18 ORY49971.1 - 2.1e-11 44.1 2.7 2.1e-11 44.1 2.7 2.2 2 1 0 2 2 2 1 Cache domain Glyco_hydro81C PF17652.1 ORY49971.1 - 0.035 13.4 0.2 0.066 12.4 0.2 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 81 C-terminal domain YL1_C PF08265.11 ORY49971.1 - 0.25 11.1 2.0 0.31 10.9 0.7 1.8 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain TPR_12 PF13424.6 ORY49972.1 - 6e-14 52.1 7.3 7.4e-07 29.4 0.5 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat VWA PF00092.28 ORY49972.1 - 1.2e-11 45.2 4.7 2.3e-11 44.3 0.2 2.7 2 1 1 3 3 3 1 von Willebrand factor type A domain VWA_2 PF13519.6 ORY49972.1 - 1.9e-10 41.3 1.2 7.3e-10 39.5 0.1 2.6 3 0 0 3 3 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 ORY49972.1 - 3.7e-09 36.7 0.5 1.5e-08 34.8 0.0 2.2 3 0 0 3 3 3 1 von Willebrand factor type A domain TPR_7 PF13176.6 ORY49972.1 - 1.7e-08 33.9 0.4 0.6 10.3 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat VWA_CoxE PF05762.14 ORY49972.1 - 9.4e-05 21.9 0.0 0.00019 20.9 0.0 1.5 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein TPR_2 PF07719.17 ORY49972.1 - 0.00012 21.9 5.3 0.22 11.7 0.5 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat DUF2201 PF09967.9 ORY49972.1 - 0.00047 20.3 0.0 0.0013 18.9 0.0 1.8 1 0 0 1 1 1 1 VWA-like domain (DUF2201) TPR_10 PF13374.6 ORY49972.1 - 0.0013 18.5 7.7 0.019 14.8 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat vWA-TerF-like PF10138.9 ORY49972.1 - 0.0067 16.6 0.1 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus TPR_8 PF13181.6 ORY49972.1 - 0.013 15.6 4.1 1.8 9.0 0.0 4.2 4 1 1 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.6 ORY49972.1 - 0.024 14.1 0.1 2.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_1 PF00515.28 ORY49972.1 - 0.26 11.2 18.2 0.39 10.6 1.1 4.7 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY49972.1 - 0.36 10.6 5.6 0.91 9.3 0.1 3.7 4 1 1 5 5 5 0 TPR repeat FIVAR PF07554.13 ORY49972.1 - 0.49 11.2 3.5 0.45 11.3 0.6 2.5 3 0 0 3 3 1 0 FIVAR domain PIF1 PF05970.14 ORY49973.1 - 4.5e-14 52.4 0.0 8.1e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 ORY49973.1 - 9.1e-12 45.1 0.0 1.4e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 ORY49973.1 - 3.6e-06 27.4 0.2 6.2e-06 26.6 0.2 1.3 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 ORY49973.1 - 0.00012 21.2 0.1 0.00021 20.4 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB UvrD-helicase PF00580.21 ORY49973.1 - 0.00028 20.5 5.4 0.0014 18.3 0.1 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain TrwB_AAD_bind PF10412.9 ORY49973.1 - 0.00032 19.7 0.1 0.00049 19.1 0.1 1.2 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain NTPase_1 PF03266.15 ORY49973.1 - 0.0005 20.0 0.5 0.0041 17.1 0.5 2.3 1 1 0 1 1 1 1 NTPase AAA_16 PF13191.6 ORY49973.1 - 0.00063 20.2 0.0 0.0013 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.7 ORY49973.1 - 0.001 18.1 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain PhoH PF02562.16 ORY49973.1 - 0.0012 18.3 0.1 0.0017 17.8 0.1 1.2 1 0 0 1 1 1 1 PhoH-like protein DUF853 PF05872.12 ORY49973.1 - 0.0056 15.3 0.0 0.01 14.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF853) DEAD PF00270.29 ORY49973.1 - 0.0057 16.4 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ABC_tran PF00005.27 ORY49973.1 - 0.0062 17.1 2.7 0.22 12.0 0.1 2.2 2 0 0 2 2 2 1 ABC transporter Helicase_RecD PF05127.14 ORY49973.1 - 0.0082 16.0 0.2 0.019 14.8 0.2 1.6 1 0 0 1 1 1 1 Helicase T2SSE PF00437.20 ORY49973.1 - 0.013 14.5 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.6 ORY49973.1 - 0.015 15.1 6.4 0.019 14.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORY49973.1 - 0.018 14.6 0.0 0.04 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ResIII PF04851.15 ORY49973.1 - 0.018 15.0 2.7 0.021 14.9 0.0 2.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 ORY49973.1 - 0.025 13.9 0.1 0.025 13.9 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 ORY49973.1 - 0.031 14.6 1.8 0.043 14.1 0.1 2.0 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 ORY49973.1 - 0.098 12.0 0.4 0.58 9.5 0.0 2.0 2 0 0 2 2 2 0 KaiC FtsK_SpoIIIE PF01580.18 ORY49973.1 - 0.13 11.6 0.2 0.3 10.4 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family FAM72 PF14976.6 ORY49974.1 - 2.5e-51 173.6 4.8 3.5e-51 173.1 4.8 1.2 1 0 0 1 1 1 1 FAM72 protein Yippee-Mis18 PF03226.14 ORY49974.1 - 2.4 8.4 9.3 7.2 6.9 9.3 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly NDT80_PhoG PF05224.12 ORY49975.1 - 0.24 11.6 3.7 0.93 9.7 1.5 2.1 2 0 0 2 2 2 0 NDT80 / PhoG like DNA-binding family Peptidase_M24 PF00557.24 ORY49977.1 - 2.7e-32 112.2 0.0 4.9e-32 111.3 0.0 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 ORY49977.1 - 0.021 14.6 0.0 0.051 13.3 0.0 1.6 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain Methyltransf_25 PF13649.6 ORY49978.1 - 1.6e-21 76.8 0.1 1.3e-20 73.8 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY49978.1 - 4.4e-20 72.1 0.0 1.9e-19 70.1 0.0 2.0 3 0 0 3 3 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY49978.1 - 6.1e-20 71.6 0.0 9e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 ORY49978.1 - 9.4e-15 54.7 0.0 1.3e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY49978.1 - 2.2e-11 43.9 0.0 3e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY49978.1 - 3.1e-10 40.7 0.0 7.3e-10 39.5 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_20 PF12147.8 ORY49978.1 - 7.2e-09 35.2 0.0 1.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.17 ORY49978.1 - 1.8e-05 24.3 0.0 0.001 18.6 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Cons_hypoth95 PF03602.15 ORY49978.1 - 0.0001 22.0 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 ORY49978.1 - 0.00036 20.1 0.1 0.0009 18.8 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_29 PF03141.16 ORY49978.1 - 0.0005 18.7 0.0 0.00067 18.3 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.7 ORY49978.1 - 0.0018 18.2 0.0 0.0029 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 ORY49978.1 - 0.0021 17.4 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 ORY49978.1 - 0.0043 16.4 0.0 0.0051 16.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 ORY49978.1 - 0.0061 16.3 0.0 0.0097 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.18 ORY49978.1 - 0.016 14.9 0.0 0.12 12.1 0.0 2.3 2 1 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_8 PF05148.15 ORY49978.1 - 0.016 15.0 0.0 0.034 14.0 0.0 1.4 2 0 0 2 2 1 0 Hypothetical methyltransferase NodS PF05401.11 ORY49978.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_24 PF13578.6 ORY49978.1 - 0.041 14.9 0.0 0.1 13.6 0.0 1.7 2 0 0 2 2 1 0 Methyltransferase domain Met_10 PF02475.16 ORY49978.1 - 0.068 12.9 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein RrnaAD PF00398.20 ORY49978.1 - 0.075 12.1 0.0 0.09 11.8 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NNMT_PNMT_TEMT PF01234.17 ORY49978.1 - 0.18 11.0 0.0 1.8 7.7 0.0 2.0 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family F-box-like PF12937.7 ORY49979.1 - 0.00044 20.1 0.1 0.0012 18.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like Rad60-SLD PF11976.8 ORY49980.1 - 9.3e-18 63.8 0.0 1.2e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 ORY49980.1 - 2.7e-08 33.4 0.0 3.5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Tox-MPTase2 PF15638.6 ORY49980.1 - 0.068 12.9 0.1 0.075 12.8 0.1 1.0 1 0 0 1 1 1 0 Metallopeptidase toxin 2 Rad60-SLD PF11976.8 ORY49981.1 - 5.5e-20 71.0 0.0 6.3e-20 70.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 ORY49981.1 - 2e-11 43.5 0.0 2.2e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family SNase PF00565.17 ORY49982.1 - 2e-40 137.6 0.0 5.2e-15 55.8 0.0 5.3 5 0 0 5 5 5 4 Staphylococcal nuclease homologue TUDOR PF00567.24 ORY49982.1 - 3.1e-11 43.4 0.0 1.1e-10 41.6 0.0 1.9 1 1 0 1 1 1 1 Tudor domain DUF5427 PF10310.9 ORY49983.1 - 2.4e-07 30.1 3.0 1.4e-06 27.5 3.4 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5427) T3SS_basalb_I PF17001.5 ORY49983.1 - 0.098 13.3 0.8 0.45 11.1 0.8 2.3 1 0 0 1 1 1 0 Type III secretion basal body protein I, YscI, HrpB, PscI Phosducin PF02114.16 ORY49984.1 - 7.4e-14 51.3 0.0 1.1e-13 50.7 0.0 1.3 1 1 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 ORY49984.1 - 0.0014 18.6 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin UBA PF00627.31 ORY49985.1 - 5.8e-10 38.9 0.8 1.4e-09 37.7 0.8 1.7 1 0 0 1 1 1 1 UBA/TS-N domain HOIP-UBA PF16678.5 ORY49985.1 - 0.071 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 HOIP UBA domain pair STI1 PF17830.1 ORY49985.1 - 7.9 6.5 20.3 1.4 8.9 4.1 3.2 2 1 0 3 3 3 0 STI1 domain Pro_isomerase PF00160.21 ORY49986.1 - 1.1e-34 120.0 0.6 2.1e-34 119.1 0.6 1.5 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPH PF13868.6 ORY49988.1 - 9.5e-68 228.3 143.1 9.5e-68 228.3 143.1 2.1 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Pertussis_S1 PF02917.14 ORY49988.1 - 3.7 7.3 5.6 21 4.8 1.3 2.4 1 1 0 2 2 2 0 Pertussis toxin, subunit 1 DNA_pol_A_exo1 PF01612.20 ORY49989.1 - 2.6e-20 72.9 0.0 5.7e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease p25-alpha PF05517.12 ORY49990.1 - 5.2e-34 117.7 1.7 5.3e-34 117.6 1.7 1.0 1 0 0 1 1 1 1 p25-alpha Ribosomal_S16 PF00886.19 ORY49993.1 - 3.6e-26 91.0 0.2 7.7e-26 89.9 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S16 Myb_DNA-binding PF00249.31 ORY49994.1 - 3.7e-38 129.5 3.4 2.3e-13 50.1 0.3 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY49994.1 - 1.8e-31 108.2 0.1 6.4e-12 45.5 0.0 3.1 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 ORY49994.1 - 4.2e-07 30.2 2.7 0.86 10.0 0.1 3.6 3 0 0 3 3 3 3 Myb/SANT-like DNA-binding domain DUF1923 PF09083.10 ORY49994.1 - 0.021 14.5 0.2 1.4 8.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1923) Rap1_C PF11626.8 ORY49994.1 - 0.024 14.7 0.7 15 5.7 0.1 3.2 1 1 2 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Mu-like_gpT PF10124.9 ORY49994.1 - 0.093 12.0 0.0 1.3 8.3 0.0 2.3 3 0 0 3 3 3 0 Mu-like prophage major head subunit gpT Myb_DNA-bind_7 PF15963.5 ORY49994.1 - 0.11 12.4 0.7 1.4 8.9 0.1 3.0 3 2 0 3 3 3 0 Myb DNA-binding like Thioredoxin PF00085.20 ORY49995.1 - 5.2e-31 106.7 2.3 7.9e-30 102.9 0.4 2.6 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_8 PF13905.6 ORY49995.1 - 7.2e-06 26.2 0.4 0.0071 16.7 0.0 4.1 4 1 1 5 5 5 2 Thioredoxin-like OST3_OST6 PF04756.13 ORY49995.1 - 4.1e-05 23.1 0.0 8.4e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 ORY49995.1 - 0.00015 22.2 0.3 0.00058 20.3 0.1 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 ORY49995.1 - 0.0038 17.1 0.2 0.012 15.5 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family AP3D1 PF06375.11 ORY49995.1 - 0.0064 16.8 4.6 0.016 15.4 4.6 1.7 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 Thioredoxin_7 PF13899.6 ORY49995.1 - 0.02 15.1 0.1 0.097 12.9 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_3 PF13192.6 ORY49995.1 - 0.03 14.4 0.3 3.1 7.9 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin domain DUF3464 PF11947.8 ORY49995.1 - 0.064 13.0 2.3 0.13 12.0 2.3 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 VQ PF05678.14 ORY49995.1 - 0.092 12.2 0.3 0.15 11.5 0.3 1.4 1 0 0 1 1 1 0 VQ motif Ribosomal_S25 PF03297.15 ORY49995.1 - 0.1 12.8 8.5 0.33 11.2 8.5 1.9 1 0 0 1 1 1 0 S25 ribosomal protein CPSF100_C PF13299.6 ORY49995.1 - 1.3 9.2 5.5 4.6 7.4 3.4 2.2 1 1 1 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Ras PF00071.22 ORY49996.1 - 1.5e-56 190.5 0.5 1.7e-56 190.3 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY49996.1 - 1.2e-20 73.9 0.0 1.9e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY49996.1 - 1.2e-08 34.6 0.1 1.3e-08 34.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY49996.1 - 1.9e-05 24.3 0.2 5.7e-05 22.7 0.1 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY49996.1 - 0.00036 20.6 0.0 0.00059 19.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY49996.1 - 0.00042 20.3 2.3 0.16 11.9 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 ORY49996.1 - 0.028 13.6 0.0 0.035 13.3 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Rap_GAP PF02145.15 ORY49997.1 - 7.8e-32 110.3 0.3 3.1e-30 105.1 0.3 2.5 1 1 0 1 1 1 1 Rap/ran-GAP Guanylate_cyc PF00211.20 ORY49999.1 - 2.6e-45 154.3 0.0 5.7e-45 153.2 0.0 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Bac_rhodopsin PF01036.18 ORY49999.1 - 1.8e-07 30.9 8.5 3.1e-07 30.2 8.5 1.4 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein HNOBA PF07701.14 ORY49999.1 - 0.18 11.2 0.2 0.28 10.6 0.2 1.2 1 0 0 1 1 1 0 Heme NO binding associated Guanylate_cyc PF00211.20 ORY50000.1 - 2.3e-49 167.5 0.0 3.8e-49 166.8 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Bac_rhodopsin PF01036.18 ORY50000.1 - 3.9e-10 39.7 11.4 7.5e-10 38.8 11.4 1.4 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein HNOBA PF07701.14 ORY50000.1 - 0.015 14.7 0.8 0.023 14.1 0.8 1.2 1 0 0 1 1 1 0 Heme NO binding associated Guanylate_cyc PF00211.20 ORY50001.1 - 6.7e-51 172.5 0.0 1.2e-50 171.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Bac_rhodopsin PF01036.18 ORY50001.1 - 8.3e-10 38.6 6.1 8.3e-10 38.6 6.1 1.5 2 0 0 2 2 2 1 Bacteriorhodopsin-like protein HNOBA PF07701.14 ORY50001.1 - 0.047 13.1 0.9 0.074 12.5 0.9 1.3 1 0 0 1 1 1 0 Heme NO binding associated DUF383 PF04063.14 ORY50001.1 - 0.077 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF383) DHODB_Fe-S_bind PF10418.9 ORY50001.1 - 0.49 10.2 5.2 1 9.2 5.2 1.6 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B AAA_22 PF13401.6 ORY50003.1 - 8.9e-08 32.5 0.0 1.9e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY50003.1 - 0.00028 21.3 0.0 0.00084 19.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 ORY50003.1 - 0.0006 19.0 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 ORY50003.1 - 0.00091 18.6 0.0 0.15 11.4 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_29 PF13555.6 ORY50003.1 - 0.0097 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY50003.1 - 0.016 15.3 0.0 0.043 13.9 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 ORY50003.1 - 0.017 15.7 0.0 0.044 14.3 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DUF927 PF06048.11 ORY50003.1 - 0.024 14.2 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF927) ATPase_2 PF01637.18 ORY50003.1 - 0.025 14.5 1.8 0.18 11.7 0.1 2.8 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 ORY50003.1 - 0.029 14.9 0.0 0.057 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORY50003.1 - 0.031 13.5 0.0 0.068 12.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DAP3 PF10236.9 ORY50003.1 - 0.036 13.2 0.0 0.067 12.4 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA PF00004.29 ORY50003.1 - 0.037 14.5 0.0 0.1 13.0 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.7 ORY50003.1 - 0.037 12.9 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain DUF815 PF05673.13 ORY50003.1 - 0.069 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_30 PF13604.6 ORY50003.1 - 0.077 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY50003.1 - 0.2 11.2 0.1 0.41 10.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Methyltransf_32 PF13679.6 ORY50005.1 - 1.1e-09 38.5 0.3 1.5e-09 38.1 0.3 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY50005.1 - 0.0011 18.6 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 ORY50005.1 - 0.0088 15.5 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 ORY50005.1 - 0.016 15.0 0.0 0.035 13.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.9 ORY50005.1 - 0.039 13.7 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_25 PF13649.6 ORY50005.1 - 0.04 14.6 0.0 0.091 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 ORY50005.1 - 0.041 13.2 0.0 0.06 12.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 ORY50005.1 - 0.082 12.7 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 ORY50006.1 - 2.1e-64 217.4 0.7 2e-63 214.3 0.7 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY50006.1 - 1.3e-32 113.2 0.0 3.4e-31 108.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 ORY50006.1 - 1e-10 41.2 0.1 3.5e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 Kinase associated domain 1 APH PF01636.23 ORY50006.1 - 4.4e-07 30.1 0.1 0.00026 21.0 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 ORY50006.1 - 9e-06 25.2 0.1 1.8e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 ORY50006.1 - 1.3e-05 24.9 0.6 2.5e-05 24.0 0.6 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 ORY50006.1 - 0.003 16.9 0.0 0.23 10.8 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 ORY50006.1 - 0.0057 15.6 0.3 0.01 14.8 0.3 1.3 1 0 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 ORY50006.1 - 0.0097 14.8 0.3 0.017 14.0 0.3 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Choline_kinase PF01633.20 ORY50006.1 - 0.013 15.1 3.5 0.22 11.1 0.6 2.3 1 1 1 2 2 2 0 Choline/ethanolamine kinase DUF771 PF05595.11 ORY50007.1 - 0.037 14.0 2.0 0.1 12.6 2.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF771) Neur_chan_memb PF02932.16 ORY50007.1 - 5.6 7.0 9.0 11 6.0 9.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CortBP2 PF09727.9 ORY50008.1 - 0.45 10.4 1.7 0.62 9.9 1.7 1.2 1 0 0 1 1 1 0 Cortactin-binding protein-2 TFIIA PF03153.13 ORY50008.1 - 4.6 7.1 11.7 5.6 6.9 11.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2039 PF10217.9 ORY50009.1 - 6.8e-29 100.1 12.2 1e-28 99.5 12.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) RNA_pol_3_Rpc31 PF11705.8 ORY50009.1 - 0.036 14.3 10.5 0.061 13.6 10.5 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Cript PF10235.9 ORY50009.1 - 0.97 10.1 19.5 0.084 13.5 11.7 2.4 1 1 0 2 2 2 0 Microtubule-associated protein CRIPT zinc-ribbons_6 PF07191.12 ORY50009.1 - 1.6 8.8 11.5 5.5 7.0 11.6 1.7 1 1 0 1 1 1 0 zinc-ribbons PPR_2 PF13041.6 ORY50010.1 - 1.5e-32 111.6 6.7 6.4e-11 42.3 0.0 9.2 9 1 2 11 11 11 5 PPR repeat family PPR PF01535.20 ORY50010.1 - 9.8e-30 100.7 13.6 0.0012 19.0 0.0 13.2 14 1 0 14 14 13 7 PPR repeat PPR_3 PF13812.6 ORY50010.1 - 3.1e-20 72.0 1.0 4.5e-10 39.5 0.0 8.0 8 1 1 9 9 9 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 ORY50010.1 - 7.2e-19 67.2 4.2 7.8e-08 31.9 0.0 7.4 8 1 0 8 8 8 4 PPR repeat PPR_long PF17177.4 ORY50010.1 - 8.7e-12 44.9 0.5 4.1e-07 29.6 0.0 4.9 4 1 0 5 5 5 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 ORY50010.1 - 0.00021 21.8 6.4 30 5.8 0.1 8.6 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY50010.1 - 0.009 16.0 4.6 18 5.7 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat ATP13 PF12921.7 ORY50010.1 - 0.015 15.1 0.3 1.4 8.8 0.0 3.9 4 0 0 4 4 4 0 Mitochondrial ATPase expression TPR_1 PF00515.28 ORY50010.1 - 0.088 12.7 0.3 0.84 9.6 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY50010.1 - 0.18 12.1 0.6 1.5 9.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 ORY50010.1 - 1.3 9.9 17.6 12 6.8 0.0 6.4 7 0 0 7 7 6 0 Tetratricopeptide repeat Homeodomain PF00046.29 ORY50011.1 - 3.3e-10 39.6 0.9 3.3e-10 39.6 0.9 2.2 3 0 0 3 3 3 1 Homeodomain Homeobox_KN PF05920.11 ORY50011.1 - 0.0096 15.8 1.4 0.022 14.6 0.1 2.2 2 0 0 2 2 2 1 Homeobox KN domain FA_hydroxylase PF04116.13 ORY50012.1 - 4e-21 75.7 18.0 4e-21 75.7 18.0 1.8 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily SIS PF01380.22 ORY50013.1 - 4.2e-56 188.4 0.5 9.8e-33 112.8 0.0 2.5 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 ORY50013.1 - 9.7e-17 61.4 0.0 2.1e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 ORY50013.1 - 1.3e-10 41.2 0.0 2.8e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 ORY50013.1 - 0.00059 18.8 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 ORY50013.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 SIS domain Rhomboid PF01694.22 ORY50014.1 - 4.7e-34 117.6 10.0 4.7e-34 117.6 10.0 1.7 3 0 0 3 3 3 1 Rhomboid family HhH-GPD PF00730.25 ORY50015.1 - 5.4e-21 75.1 0.0 8.7e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 ORY50015.1 - 4.5e-15 55.6 0.0 1.4e-14 54.0 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain HHH PF00633.23 ORY50015.1 - 0.00037 20.2 0.2 0.0011 18.7 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 ORY50015.1 - 0.011 16.1 6.0 0.011 16.1 6.0 1.9 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III HHH_5 PF14520.6 ORY50015.1 - 0.09 13.4 0.0 0.36 11.5 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain Guanylate_cyc PF00211.20 ORY50017.1 - 4.7e-47 160.0 0.0 7.3e-47 159.4 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HNOBA PF07701.14 ORY50017.1 - 0.0018 17.8 0.3 0.0027 17.2 0.3 1.2 1 0 0 1 1 1 1 Heme NO binding associated CBFD_NFYB_HMF PF00808.23 ORY50018.1 - 5.6e-10 39.4 0.2 1.1e-09 38.5 0.2 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 ORY50018.1 - 4.7e-06 27.0 0.1 4.7e-06 27.0 0.1 2.1 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 BUD22 PF09073.10 ORY50018.1 - 0.0088 15.4 15.8 0.024 14.0 14.2 2.0 2 0 0 2 2 2 1 BUD22 Spt20 PF12090.8 ORY50018.1 - 6 6.4 25.5 0.5 9.9 0.1 2.6 2 1 0 2 2 2 0 Spt20 family CDC45 PF02724.14 ORY50018.1 - 9.3 4.4 10.3 16 3.6 10.3 1.4 1 0 0 1 1 1 0 CDC45-like protein RNA_pol_3_Rpc31 PF11705.8 ORY50018.1 - 9.3 6.4 25.0 0.16 12.2 16.6 2.1 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 FAD_binding_3 PF01494.19 ORY50019.1 - 5.4e-25 88.4 0.1 6.3e-12 45.4 0.1 3.1 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 ORY50019.1 - 3.7e-10 39.9 0.3 1.7e-06 27.9 0.2 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY50019.1 - 8.1e-08 31.9 0.1 6.9e-05 22.3 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY50019.1 - 2.3e-06 27.7 0.1 4.8e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY50019.1 - 4.2e-06 26.2 0.5 0.00036 19.9 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 ORY50019.1 - 5.2e-05 22.4 0.0 0.0011 18.0 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Amino_oxidase PF01593.24 ORY50019.1 - 0.00018 21.0 0.0 0.15 11.3 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 ORY50019.1 - 0.00078 18.3 0.3 0.0014 17.4 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 ORY50019.1 - 0.00083 19.9 0.3 0.035 14.6 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 ORY50019.1 - 0.00084 19.4 0.1 0.18 11.8 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 ORY50019.1 - 0.0029 16.7 0.4 0.0046 16.1 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 ORY50019.1 - 0.0037 16.6 0.6 0.035 13.4 0.2 2.3 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 ORY50019.1 - 0.0047 16.6 0.1 0.0086 15.7 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 ORY50019.1 - 0.0056 16.3 0.1 0.013 15.1 0.1 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Thi4 PF01946.17 ORY50019.1 - 0.0058 15.9 0.1 0.01 15.1 0.1 1.3 1 0 0 1 1 1 1 Thi4 family UDPG_MGDP_dh_N PF03721.14 ORY50019.1 - 0.0067 16.0 0.1 0.013 15.1 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 ORY50019.1 - 0.0089 16.4 0.1 0.018 15.5 0.1 1.6 1 1 0 1 1 1 1 Putative NAD(P)-binding Glu_dehyd_C PF16912.5 ORY50019.1 - 0.009 15.5 0.0 0.41 10.1 0.0 2.2 2 0 0 2 2 2 1 Glucose dehydrogenase C-terminus 3HCDH_N PF02737.18 ORY50019.1 - 0.02 14.8 0.2 0.033 14.1 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 ORY50019.1 - 0.03 13.7 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 ORY50019.1 - 0.055 12.5 0.3 0.082 12.0 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HGTP_anticodon PF03129.20 ORY50019.1 - 0.069 13.3 0.0 0.26 11.5 0.0 1.9 2 0 0 2 2 2 0 Anticodon binding domain XdhC_C PF13478.6 ORY50019.1 - 0.12 12.9 0.0 0.2 12.2 0.0 1.3 1 0 0 1 1 1 0 XdhC Rossmann domain NAD_binding_2 PF03446.15 ORY50019.1 - 0.12 12.5 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 ORY50019.1 - 0.17 12.2 0.1 0.34 11.2 0.1 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Lycopene_cycl PF05834.12 ORY50019.1 - 0.17 10.9 0.0 1.2 8.1 0.1 2.2 3 0 0 3 3 3 0 Lycopene cyclase protein TrkA_N PF02254.18 ORY50019.1 - 0.17 12.2 0.1 0.39 11.0 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Aminotran_5 PF00266.19 ORY50020.1 - 7.3e-07 28.5 0.0 3.1e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Pyridoxal_deC PF00282.19 ORY50020.1 - 0.00015 20.6 0.0 0.0094 14.7 0.0 2.7 2 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Il2rg PF15874.5 ORY50020.1 - 0.052 13.8 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative Interleukin 2 receptor, gamma chain DUF2408 PF10303.9 ORY50021.1 - 4.7e-21 75.8 0.6 3.6e-07 30.8 0.0 5.8 2 1 2 5 5 5 5 Protein of unknown function (DUF2408) UPF0061 PF02696.14 ORY50022.1 - 3.1e-108 362.5 0.0 3e-94 316.4 0.0 3.1 3 0 0 3 3 3 3 Uncharacterized ACR, YdiU/UPF0061 family RHH_5 PF07878.11 ORY50022.1 - 0.11 12.4 0.1 0.3 11.0 0.1 1.7 1 0 0 1 1 1 0 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 DUF4743 PF15916.5 ORY50023.1 - 3.7e-09 36.6 0.0 5.6e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 ORY50023.1 - 2.1e-07 31.0 0.0 3.8e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain CPSF_A PF03178.15 ORY50025.1 - 2.5e-78 263.6 0.0 5.1e-78 262.6 0.0 1.5 1 0 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 ORY50025.1 - 2.9e-17 62.5 0.0 1.5e-12 47.0 0.0 2.3 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term CtnDOT_TraJ PF07863.11 ORY50026.1 - 0.031 14.9 2.3 0.06 14.0 2.3 1.6 1 0 0 1 1 1 0 Homologues of TraJ from Bacteroides conjugative transposon Adap_comp_sub PF00928.21 ORY50027.1 - 6.7e-47 160.1 0.1 1.4e-46 159.1 0.1 1.4 1 1 0 1 1 1 1 Adaptor complexes medium subunit family ABC_tran PF00005.27 ORY50027.1 - 8.3e-18 65.2 0.2 2.1e-17 63.9 0.2 1.7 1 1 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 ORY50027.1 - 5.1e-09 35.8 10.4 1.2e-08 34.7 10.4 1.6 1 0 0 1 1 1 1 ABC-2 type transporter RsgA_GTPase PF03193.16 ORY50027.1 - 0.00018 21.4 0.0 0.00034 20.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 ORY50027.1 - 0.00055 19.1 0.0 0.00085 18.5 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 ORY50027.1 - 0.0031 17.8 0.0 0.0063 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 ORY50027.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY50027.1 - 0.018 14.8 0.3 0.046 13.5 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 ORY50027.1 - 0.018 15.2 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Clat_adaptor_s PF01217.20 ORY50027.1 - 0.035 14.0 0.8 0.065 13.2 0.8 1.4 1 0 0 1 1 1 0 Clathrin adaptor complex small chain AAA_25 PF13481.6 ORY50027.1 - 0.044 13.4 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ORY50027.1 - 0.047 14.2 0.0 0.087 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 ORY50027.1 - 0.073 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY50027.1 - 0.086 12.6 0.1 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORY50027.1 - 0.098 12.4 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 ORY50027.1 - 0.15 11.8 0.2 19 5.0 0.0 2.2 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 ORY50027.1 - 0.2 11.2 0.0 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TPR_2 PF07719.17 ORY50028.1 - 1.2e-11 43.8 7.4 0.02 15.0 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY50028.1 - 3.4e-10 39.9 16.9 0.94 10.5 0.1 9.1 7 3 3 10 10 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY50028.1 - 5.4e-07 29.2 0.5 0.0015 18.4 0.0 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY50028.1 - 1.3e-06 28.1 4.2 0.25 11.7 0.0 5.9 7 0 0 7 7 5 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 ORY50028.1 - 7.6e-06 25.9 9.0 0.13 12.2 0.0 5.9 7 0 0 7 7 7 1 Mad3/BUB1 homology region 1 TPR_1 PF00515.28 ORY50028.1 - 2.8e-05 23.7 5.9 0.34 10.8 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY50028.1 - 4.8e-05 22.9 0.6 0.15 11.8 0.0 3.9 5 0 0 5 5 5 2 TPR repeat RPN7 PF10602.9 ORY50028.1 - 5.6e-05 22.9 0.6 0.0054 16.5 0.0 3.1 3 0 0 3 3 2 1 26S proteasome subunit RPN7 TPR_12 PF13424.6 ORY50028.1 - 0.00013 22.1 9.6 0.25 11.7 0.0 5.4 5 2 1 6 6 5 2 Tetratricopeptide repeat Suf PF05843.14 ORY50028.1 - 0.001 19.1 26.8 0.56 10.1 0.0 6.8 5 3 1 6 6 6 3 Suppressor of forked protein (Suf) TPR_10 PF13374.6 ORY50028.1 - 0.0049 16.7 3.6 0.5 10.3 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat SNAP PF14938.6 ORY50028.1 - 0.015 14.8 3.7 0.15 11.5 0.1 3.7 3 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP PPR PF01535.20 ORY50028.1 - 0.039 14.2 1.8 0.61 10.5 0.0 4.0 6 0 0 6 6 4 0 PPR repeat TPR_9 PF13371.6 ORY50028.1 - 0.11 12.7 5.4 12 6.1 0.0 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY50028.1 - 0.11 13.2 1.5 31 5.5 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORY50028.1 - 0.23 11.9 6.0 1.4 9.5 0.0 5.1 7 0 0 7 7 6 0 Tetratricopeptide repeat AHL_synthase PF17327.2 ORY50028.1 - 0.26 10.3 3.5 0.46 9.4 3.5 1.3 1 0 0 1 1 1 0 Acyl homoserine lactone synthase HAT PF02184.16 ORY50028.1 - 3.1 7.8 13.8 62 3.7 0.0 6.6 8 0 0 8 8 8 0 HAT (Half-A-TPR) repeat PRIMA1 PF16101.5 ORY50028.1 - 3.1 7.9 9.3 1.7 8.7 6.7 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 NRDE-2 PF08424.10 ORY50028.1 - 8.4 5.4 20.2 0.77 8.8 0.1 5.9 5 2 0 6 6 5 0 NRDE-2, necessary for RNA interference Glyco_transf_90 PF05686.12 ORY50029.1 - 1.1e-27 97.0 0.0 1.5e-23 83.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 90 ABC_tran PF00005.27 ORY50030.1 - 3e-12 47.2 1.5 2.9e-11 44.1 1.5 2.2 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 ORY50030.1 - 0.00014 21.8 0.1 0.00028 20.8 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 ORY50030.1 - 0.0077 15.9 0.3 0.02 14.6 0.3 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY50030.1 - 0.0082 16.2 0.2 0.023 14.7 0.2 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase T2SSE PF00437.20 ORY50030.1 - 0.019 14.0 0.1 0.031 13.3 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.6 ORY50030.1 - 0.019 14.5 0.1 0.037 13.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORY50030.1 - 0.021 14.6 0.5 0.037 13.7 0.5 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 ORY50030.1 - 0.025 14.2 0.3 0.73 9.4 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 ORY50030.1 - 0.027 14.7 0.0 0.053 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY50030.1 - 0.029 14.8 0.0 0.053 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 ORY50030.1 - 0.056 13.9 0.2 0.056 13.9 0.2 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ORY50030.1 - 0.065 12.9 0.4 0.12 12.0 0.4 1.4 1 0 0 1 1 1 0 AAA domain DUF327 PF03885.13 ORY50030.1 - 0.076 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF327) PDR_CDR PF06422.12 ORY50030.1 - 0.082 12.8 0.3 0.082 12.8 0.3 1.9 2 0 0 2 2 1 0 CDR ABC transporter ATPase PF06745.13 ORY50030.1 - 0.12 11.7 0.1 0.74 9.1 0.1 2.0 2 0 0 2 2 2 0 KaiC Fructosamin_kin PF03881.14 ORY50030.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase AAA_11 PF13086.6 ORY50030.1 - 0.17 11.6 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ORY50031.1 - 4e-18 66.2 0.2 1.4e-17 64.5 0.2 1.9 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 ORY50031.1 - 0.00014 21.8 0.2 0.00033 20.6 0.2 1.6 1 1 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 ORY50031.1 - 0.0009 18.4 0.1 0.0013 17.8 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein MMR_HSR1 PF01926.23 ORY50031.1 - 0.0032 17.5 0.2 0.011 15.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 ORY50031.1 - 0.0046 17.2 0.0 0.0087 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 ORY50031.1 - 0.0081 15.9 0.3 0.017 14.9 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RIFIN PF02009.16 ORY50031.1 - 0.0088 16.0 0.3 0.015 15.2 0.3 1.2 1 0 0 1 1 1 1 Rifin AAA_33 PF13671.6 ORY50031.1 - 0.0095 16.1 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ORY50031.1 - 0.034 13.7 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Stevor PF17410.2 ORY50031.1 - 0.035 13.7 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame AAA_30 PF13604.6 ORY50031.1 - 0.036 13.8 0.1 0.068 12.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY50031.1 - 0.062 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ORY50031.1 - 0.079 13.4 0.1 0.079 13.4 0.1 1.9 1 1 0 2 2 2 0 AAA domain cobW PF02492.19 ORY50031.1 - 0.12 11.9 0.1 0.59 9.7 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 ORY50031.1 - 0.13 12.0 0.2 10 5.8 0.1 2.2 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORY50031.1 - 0.13 12.6 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 ORY50031.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 ORY50031.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_11 PF13086.6 ORY50031.1 - 0.28 11.0 0.0 0.28 11.0 0.0 1.4 2 0 0 2 2 1 0 AAA domain DUF443 PF04276.12 ORY50031.1 - 0.3 10.9 0.1 0.3 10.9 0.1 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF443) Ank_2 PF12796.7 ORY50032.1 - 5.3e-10 39.8 0.1 2.7e-07 31.1 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORY50032.1 - 2.6e-07 30.8 0.1 0.0033 17.8 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 ORY50032.1 - 2.4e-06 27.5 0.0 0.11 13.1 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 ORY50032.1 - 0.0012 19.4 0.1 0.0063 17.1 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY50032.1 - 0.0027 18.0 0.5 0.21 11.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) HMGL-like PF00682.19 ORY50032.1 - 0.03 13.9 0.1 0.045 13.3 0.1 1.2 1 0 0 1 1 1 0 HMGL-like Ank PF00023.30 ORY50033.1 - 0.0071 16.8 0.0 1.8 9.1 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 ORY50033.1 - 0.012 16.2 0.0 0.67 10.6 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY50033.1 - 0.031 14.6 0.0 0.7 10.3 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY50033.1 - 0.042 14.4 0.0 0.075 13.6 0.0 1.5 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY50033.1 - 0.12 13.0 0.2 4.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat FAD_binding_3 PF01494.19 ORY50034.1 - 0.0015 17.8 0.0 0.0022 17.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain 60KD_IMP PF02096.20 ORY50036.1 - 1.6e-06 28.1 0.1 0.00033 20.6 0.0 2.1 2 0 0 2 2 2 2 60Kd inner membrane protein ABC_tran PF00005.27 ORY50037.1 - 3.4e-21 76.2 0.1 6.1e-21 75.4 0.1 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 ORY50037.1 - 0.00018 21.5 0.2 0.00033 20.6 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase RNA_helicase PF00910.22 ORY50037.1 - 0.0014 19.0 0.0 0.0028 18.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 ORY50037.1 - 0.005 16.6 0.4 0.011 15.4 0.4 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 ORY50037.1 - 0.0061 16.6 0.1 0.012 15.7 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY50037.1 - 0.0065 16.9 0.0 0.018 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 ORY50037.1 - 0.011 15.4 0.2 0.025 14.3 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 ORY50037.1 - 0.013 15.1 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY50037.1 - 0.022 14.5 0.0 0.083 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ORY50037.1 - 0.027 14.7 0.1 0.068 13.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 ORY50037.1 - 0.038 13.1 0.2 0.07 12.2 0.2 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 ORY50037.1 - 0.043 14.3 0.1 0.086 13.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain ISK_Channel PF02060.15 ORY50037.1 - 0.088 12.5 0.9 0.19 11.4 0.9 1.5 1 0 0 1 1 1 0 Slow voltage-gated potassium channel ABC2_membrane PF01061.24 ORY50037.1 - 0.34 10.3 12.0 0.78 9.1 12.0 1.6 1 1 0 1 1 1 0 ABC-2 type transporter EAP30 PF04157.16 ORY50038.1 - 4.5e-38 130.9 0.0 6.4e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family RPW8 PF05659.11 ORY50038.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DZR PF12773.7 ORY50038.1 - 0.11 12.5 1.3 0.2 11.7 1.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-RanBP PF00641.18 ORY50038.1 - 0.23 10.8 0.8 0.42 10.0 0.8 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others ABC_tran PF00005.27 ORY50039.1 - 3.4e-12 47.0 0.0 6.8e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 ORY50039.1 - 7.2e-08 32.1 6.6 7.2e-08 32.1 6.6 1.8 2 0 0 2 2 2 1 ABC-2 type transporter RsgA_GTPase PF03193.16 ORY50039.1 - 0.00022 21.1 0.1 0.00072 19.5 0.1 1.6 1 1 1 2 2 2 1 RsgA GTPase RNA_helicase PF00910.22 ORY50039.1 - 0.0023 18.3 0.0 0.0058 17.0 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_29 PF13555.6 ORY50039.1 - 0.0041 16.8 0.2 0.0082 15.9 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY50039.1 - 0.011 15.8 0.0 0.09 12.9 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.6 ORY50039.1 - 0.016 15.3 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY50039.1 - 0.036 13.8 0.2 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 ORY50039.1 - 0.046 14.2 0.3 0.082 13.4 0.3 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 ORY50039.1 - 0.052 13.8 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORY50039.1 - 0.083 12.6 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORY50039.1 - 0.092 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ORY50039.1 - 0.17 11.8 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain T2SSE PF00437.20 ORY50039.1 - 0.19 10.8 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 ORY50039.1 - 0.21 12.0 0.0 0.35 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 ORY50039.1 - 0.22 11.1 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 ORY50039.1 - 0.23 10.9 0.0 0.35 10.3 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain VASt PF16016.5 ORY50040.1 - 1.3e-15 58.1 3.4 2.1e-13 50.9 1.1 2.3 1 1 1 2 2 2 2 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 ORY50041.1 - 2.4e-14 53.6 0.1 4.1e-14 52.9 0.1 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 ORY50041.1 - 1.4e-10 41.6 0.1 5.6e-10 39.7 0.1 2.1 1 0 0 1 1 1 1 PH domain GRAM PF02893.20 ORY50041.1 - 6.7e-10 38.9 0.1 1.5e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 GRAM domain PH_8 PF15409.6 ORY50041.1 - 1.8e-06 28.1 0.5 3.8e-06 27.1 0.5 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain BAR PF03114.18 ORY50041.1 - 4.6e-06 26.5 0.2 9.5e-06 25.4 0.2 1.4 1 0 0 1 1 1 1 BAR domain PH_11 PF15413.6 ORY50041.1 - 0.00018 21.9 1.9 0.0014 19.0 1.9 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain BAR_2 PF10455.9 ORY50041.1 - 0.017 14.3 0.1 0.017 14.3 0.1 1.6 2 0 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Gp49 PF05973.14 ORY50041.1 - 0.1 12.8 0.2 0.29 11.3 0.0 1.9 2 0 0 2 2 2 0 Phage derived protein Gp49-like (DUF891) Cwf_Cwc_15 PF04889.12 ORY50041.1 - 0.16 11.7 6.5 0.34 10.6 6.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3295 PF11702.8 ORY50041.1 - 0.34 10.2 4.3 0.58 9.5 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DUF4611 PF15387.6 ORY50041.1 - 1.8 8.8 8.3 13 6.0 6.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) dCache_2 PF08269.11 ORY50042.1 - 0.17 11.1 0.0 0.35 10.0 0.0 1.5 1 0 0 1 1 1 0 Cache domain SMC_ScpB PF04079.16 ORY50042.1 - 0.31 10.6 2.4 9.5 5.8 0.1 2.4 2 0 0 2 2 2 0 Segregation and condensation complex subunit ScpB SOGA PF11365.8 ORY50042.1 - 0.34 12.1 9.4 0.51 11.5 0.6 3.1 3 0 0 3 3 3 0 Protein SOGA TMF_DNA_bd PF12329.8 ORY50042.1 - 0.43 10.6 5.6 1.7 8.7 1.0 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Collectrin PF16959.5 ORY50042.1 - 0.66 9.7 2.7 9.3 6.0 0.1 3.0 2 1 1 3 3 3 0 Renal amino acid transporter Lzipper-MIP1 PF14389.6 ORY50042.1 - 1.4 9.2 8.4 4.8 7.6 0.4 3.7 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF4085 PF13315.6 ORY50042.1 - 3.4 7.2 4.9 2.1 7.9 0.1 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF4085) Snapin_Pallidin PF14712.6 ORY50042.1 - 4 7.9 8.8 0.47 10.9 0.2 3.0 3 0 0 3 3 3 0 Snapin/Pallidin SNARE PF05739.19 ORY50043.1 - 0.0039 17.2 0.1 0.012 15.6 0.1 1.9 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 ORY50043.1 - 0.022 14.5 0.4 0.043 13.5 0.4 1.5 1 0 0 1 1 1 0 Membrane fusion protein Use1 RPN13_C PF16550.5 ORY50043.1 - 0.042 14.0 0.0 0.088 13.0 0.0 1.5 1 0 0 1 1 1 0 UCH-binding domain Syntaxin PF00804.25 ORY50043.1 - 0.077 12.7 1.4 0.18 11.4 0.6 2.1 2 0 0 2 2 2 0 Syntaxin Phosphoesterase PF04185.14 ORY50044.1 - 1.3e-20 73.9 0.3 1.5e-15 57.2 0.2 2.2 2 0 0 2 2 2 2 Phosphoesterase family peroxidase PF00141.23 ORY50045.1 - 2.1e-28 99.6 0.0 3.2e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Peroxidase CFEM PF05730.11 ORY50045.1 - 2.5e-05 24.3 4.4 7.2e-05 22.8 4.4 1.8 1 1 0 1 1 1 1 CFEM domain Acetyltransf_4 PF13420.7 ORY50046.1 - 0.12 12.6 0.0 0.13 12.4 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GREB1 PF15782.5 ORY50047.1 - 0.73 6.9 12.7 0.9 6.6 12.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Ndc1_Nup PF09531.10 ORY50047.1 - 3.8 6.1 11.0 4.7 5.8 11.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.9 ORY50047.1 - 9.7 4.6 7.4 11 4.4 7.4 1.0 1 0 0 1 1 1 0 Macoilin family ArfGap PF01412.18 ORY50048.1 - 9.1e-08 32.2 1.0 1.6e-06 28.2 1.1 2.4 1 1 1 2 2 2 1 Putative GTPase activating protein for Arf ARD PF03079.14 ORY50049.1 - 4.2e-50 170.0 0.3 5.5e-50 169.6 0.3 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 ORY50049.1 - 2.8e-10 39.7 0.0 4.6e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 ORY50049.1 - 7.2e-07 29.2 0.0 1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 ORY50049.1 - 0.0023 17.6 0.0 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 Cupin 3-HAO PF06052.12 ORY50049.1 - 0.033 13.8 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase Cupin_8 PF13621.6 ORY50049.1 - 0.055 13.2 0.0 0.14 11.8 0.0 1.5 1 1 0 1 1 1 0 Cupin-like domain Cupin_6 PF12852.7 ORY50049.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_3 PF05899.12 ORY50049.1 - 0.17 11.6 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) EF1_GNE PF00736.19 ORY50050.1 - 3.3e-35 120.1 0.7 3.3e-35 120.1 0.7 1.8 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 ORY50050.1 - 5.5e-10 39.5 9.1 5.5e-10 39.5 9.1 2.2 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region CTC1 PF15489.6 ORY50051.1 - 2.4e-10 38.7 0.3 6.3e-08 30.7 0.0 2.1 2 0 0 2 2 2 2 CST, telomere maintenance, complex subunit CTC1 Mito_carr PF00153.27 ORY50052.1 - 4.3e-20 71.4 1.8 1.6e-11 43.9 0.0 3.8 2 1 1 3 3 3 3 Mitochondrial carrier protein Sporozoite_P67 PF05642.11 ORY50053.1 - 7.2 4.6 6.3 8 4.4 6.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ank_2 PF12796.7 ORY50054.1 - 1.3e-133 435.9 43.2 5.2e-12 46.2 0.1 22.6 7 6 17 26 26 26 25 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY50054.1 - 1.8e-86 283.5 26.4 1.4e-07 31.9 0.0 28.9 22 6 11 33 33 33 19 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY50054.1 - 2e-74 244.7 34.9 2.7e-07 30.7 0.0 27.9 20 6 10 31 31 30 18 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY50054.1 - 2.1e-64 205.8 10.1 0.21 12.3 0.0 36.0 38 0 0 38 38 37 11 Ankyrin repeat Ank PF00023.30 ORY50054.1 - 1.2e-38 129.9 33.7 0.039 14.4 0.1 26.8 26 2 1 27 27 27 7 Ankyrin repeat TIR_2 PF13676.6 ORY50054.1 - 1.6e-05 25.5 0.0 9.1e-05 23.1 0.0 2.3 1 1 0 1 1 1 1 TIR domain DUF1186 PF06685.11 ORY50054.1 - 0.047 13.1 3.0 0.29 10.5 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1186) Sacchrp_dh_NADP PF03435.18 ORY50054.1 - 0.18 12.1 0.6 3.2 8.0 0.0 3.5 4 0 0 4 4 4 0 Saccharopine dehydrogenase NADP binding domain APC_u15 PF16636.5 ORY50054.1 - 0.27 11.7 6.5 0.68 10.4 6.5 1.7 1 0 0 1 1 1 0 Unstructured region on APC between APC_crr regions 5 and 6 Nop14 PF04147.12 ORY50054.1 - 1.8 6.7 12.0 2.9 6.0 12.0 1.2 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.13 ORY50054.1 - 7 5.5 13.0 12 4.7 13.0 1.3 1 0 0 1 1 1 0 Paf1 Abhydrolase_1 PF00561.20 ORY50055.1 - 7.2e-13 48.8 0.0 1.4e-12 47.9 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY50055.1 - 3.4e-12 47.4 0.1 4.2e-12 47.1 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY50055.1 - 4.8e-09 35.8 0.0 6.2e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 ORY50055.1 - 0.0059 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 ORY50055.1 - 0.016 14.8 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_2 PF02230.16 ORY50055.1 - 0.02 14.7 0.0 0.075 12.8 0.0 1.8 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 ORY50055.1 - 0.043 13.7 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 ORY50055.1 - 0.17 10.8 0.0 0.28 10.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme RSN1_7TM PF02714.15 ORY50056.1 - 4.3e-52 177.1 24.0 4.3e-52 177.1 24.0 2.5 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 ORY50056.1 - 4.5e-23 81.7 24.5 8.9e-21 74.3 0.2 5.2 4 1 1 5 5 5 2 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 ORY50056.1 - 1.4e-19 71.0 0.0 2.7e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter GST_N PF02798.20 ORY50057.1 - 0.00026 21.3 0.0 0.0054 17.0 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY50057.1 - 0.0077 16.5 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY50057.1 - 0.011 16.1 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY50057.1 - 0.014 15.6 1.5 0.96 9.7 1.1 2.6 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 ORY50057.1 - 0.17 12.2 0.0 0.22 11.8 0.0 1.3 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein zf-MYND PF01753.18 ORY50058.1 - 1.3e-08 34.8 2.0 1.7e-08 34.4 2.0 1.2 1 0 0 1 1 1 1 MYND finger Rubis-subs-bind PF09273.11 ORY50058.1 - 0.00073 20.2 0.0 0.00096 19.8 0.0 1.2 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding zf-C6H2 PF15801.5 ORY50058.1 - 0.0011 19.2 0.8 0.0017 18.6 0.8 1.2 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding SET PF00856.28 ORY50059.1 - 5.6e-10 39.9 0.0 9.4e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 SET domain DNA_methylase PF00145.17 ORY50063.1 - 9.1e-16 58.1 0.0 2.8e-14 53.2 0.0 2.0 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Pkinase PF00069.25 ORY50065.1 - 8.3e-77 258.1 0.0 1.1e-76 257.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY50065.1 - 4.4e-34 117.9 0.0 5.7e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 ORY50065.1 - 3.1e-18 65.9 0.3 6.9e-18 64.8 0.3 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 ORY50065.1 - 2e-05 24.0 0.0 0.00022 20.6 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 ORY50065.1 - 7e-05 22.3 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Yop-YscD_cpl PF16697.5 ORY50065.1 - 9.1e-05 22.7 0.1 0.00036 20.8 0.1 1.9 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 ORY50065.1 - 0.00017 20.5 0.0 0.0003 19.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FHA_2 PF17913.1 ORY50065.1 - 0.037 14.3 0.2 0.17 12.2 0.0 2.1 2 0 0 2 2 2 0 FHA domain YrbL-PhoP_reg PF10707.9 ORY50065.1 - 0.046 13.2 0.2 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL APH PF01636.23 ORY50065.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mannosyl_trans3 PF11051.8 ORY50066.1 - 2.2e-35 122.3 0.0 9.4e-35 120.3 0.0 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.16 ORY50066.1 - 0.13 12.2 2.9 1.6 8.7 0.0 3.2 4 0 0 4 4 4 0 Nucleotide-diphospho-sugar transferase Glyco_hydro_18 PF00704.28 ORY50067.1 - 4.3e-09 36.5 8.0 3.9e-07 30.1 0.1 3.7 3 1 1 4 4 4 2 Glycosyl hydrolases family 18 Mannosyl_trans3 PF11051.8 ORY50068.1 - 8.1e-28 97.6 0.2 2.9e-26 92.4 0.2 2.8 1 1 0 1 1 1 1 Mannosyltransferase putative DUF5358 PF17311.2 ORY50068.1 - 0.037 14.0 0.1 0.075 13.0 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5358) Transketolase_N PF00456.21 ORY50069.1 - 3e-109 365.0 0.3 4.4e-109 364.5 0.3 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 ORY50069.1 - 4.4e-40 137.3 0.0 1.7e-39 135.3 0.0 2.0 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 ORY50069.1 - 3.6e-10 39.8 0.3 1.3e-09 38.0 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 ORY50069.1 - 5.8e-08 32.3 0.1 1.1e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 ORY50069.1 - 4.7e-07 29.1 0.3 7.7e-07 28.4 0.3 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 ORY50069.1 - 0.00066 19.5 0.2 0.0089 15.8 0.5 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Epiglycanin_C PF14654.6 ORY50070.1 - 0.12 12.4 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Lactamase_B PF00753.27 ORY50071.1 - 3.3e-15 56.6 0.5 1.1e-14 54.9 0.5 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY50071.1 - 0.0039 16.7 0.1 0.014 14.9 0.1 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DUF3895 PF13034.6 ORY50071.1 - 0.0087 16.0 0.1 0.04 13.9 0.0 2.2 2 1 1 3 3 3 1 Protein of unknown function (DUF3895) DUF4863 PF16155.5 ORY50071.1 - 0.062 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4863) OspE PF02471.17 ORY50071.1 - 0.1 12.8 0.4 1.1 9.6 0.0 2.5 3 0 0 3 3 3 0 Borrelia outer surface protein E Ras PF00071.22 ORY50072.1 - 3.4e-65 218.6 0.2 4.1e-65 218.3 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY50072.1 - 6.4e-36 123.2 0.0 1.1e-35 122.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY50072.1 - 5e-16 58.6 0.2 6.3e-16 58.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY50072.1 - 2.9e-07 30.2 0.3 7.4e-07 28.9 0.2 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 ORY50072.1 - 1.6e-06 27.7 0.1 1.9e-06 27.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY50072.1 - 1.9e-05 24.7 0.2 0.00015 21.8 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY50072.1 - 5.4e-05 23.2 0.2 0.27 11.1 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 ORY50072.1 - 0.0018 17.7 0.1 0.0022 17.4 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 ORY50072.1 - 0.0021 17.6 0.0 0.02 14.4 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B G-alpha PF00503.20 ORY50072.1 - 0.0036 16.5 4.2 0.075 12.2 1.3 3.0 1 1 1 2 2 2 1 G-protein alpha subunit ATP_bind_1 PF03029.17 ORY50072.1 - 0.02 14.7 0.0 0.053 13.3 0.0 1.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 ORY50072.1 - 0.053 13.3 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 ORY50072.1 - 0.088 11.9 0.1 0.24 10.5 0.0 1.7 3 0 0 3 3 3 0 MCM P-loop domain AAA_16 PF13191.6 ORY50072.1 - 0.097 13.1 0.0 0.12 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ORY50072.1 - 0.15 12.3 0.0 0.47 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain ING PF12998.7 ORY50073.1 - 7.6e-21 74.6 0.1 1.1e-20 74.1 0.1 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 ORY50073.1 - 2.7e-06 27.2 8.9 4.4e-06 26.5 8.9 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 ORY50073.1 - 0.015 15.6 0.8 0.026 14.8 0.8 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF5344 PF17279.2 ORY50073.1 - 0.049 14.2 0.0 0.086 13.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5344) zf-4CXXC_R1 PF10497.9 ORY50073.1 - 1.2 9.4 5.4 4.4 7.6 5.4 1.9 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_2 PF13639.6 ORY50073.1 - 3.3 8.1 6.0 5.6 7.4 6.0 1.3 1 0 0 1 1 1 0 Ring finger domain Dor1 PF04124.12 ORY50075.1 - 3e-68 230.0 2.5 5.7e-68 229.1 2.5 1.4 1 0 0 1 1 1 1 Dor1-like family Sod_Fe_C PF02777.18 ORY50076.1 - 3.6e-39 133.0 0.3 7.3e-39 132.1 0.3 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 ORY50076.1 - 1.3e-30 105.7 2.4 2.5e-30 104.7 2.4 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain EMP24_GP25L PF01105.24 ORY50077.1 - 3.4e-41 141.2 0.2 3.9e-41 141.0 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Abhydrolase_3 PF07859.13 ORY50078.1 - 4.7e-40 137.7 0.0 5.6e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY50078.1 - 2.5e-06 26.6 0.0 2.6e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 ORY50078.1 - 0.0079 15.7 0.0 0.019 14.4 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 ORY50079.1 - 3.1e-29 102.4 0.0 4.2e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY50079.1 - 1.7e-05 23.8 0.0 0.00048 19.1 0.0 2.4 2 1 0 2 2 2 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 ORY50079.1 - 0.086 12.6 0.1 0.88 9.3 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 ORY50080.1 - 5.2e-31 108.2 0.0 7.1e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY50080.1 - 4.5e-09 35.6 0.1 0.00045 19.2 0.0 2.4 3 0 0 3 3 3 2 Steryl acetyl hydrolase Abhydrolase_1 PF00561.20 ORY50081.1 - 1.5e-20 73.9 0.2 1.2e-17 64.4 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY50081.1 - 7.3e-18 66.0 1.8 8.8e-18 65.7 1.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY50081.1 - 3.7e-11 42.8 0.3 5.3e-11 42.2 0.3 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 ORY50081.1 - 2.8e-08 33.1 0.0 3.9e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase PGAP1 PF07819.13 ORY50081.1 - 3.1e-05 23.8 0.1 0.00012 21.9 0.1 1.8 1 1 0 1 1 1 1 PGAP1-like protein Chlorophyllase2 PF12740.7 ORY50081.1 - 9.4e-05 21.4 0.0 0.00014 20.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.20 ORY50081.1 - 0.00014 21.6 0.1 0.0035 17.0 0.0 2.2 2 0 0 2 2 2 1 Putative esterase Thioesterase PF00975.20 ORY50081.1 - 0.0006 20.0 0.0 0.001 19.2 0.0 1.5 1 1 0 1 1 1 1 Thioesterase domain Abhydro_lipase PF04083.16 ORY50081.1 - 0.00078 19.0 0.0 0.0022 17.6 0.0 1.7 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region DLH PF01738.18 ORY50081.1 - 0.013 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Palm_thioest PF02089.15 ORY50081.1 - 0.046 13.5 0.0 0.056 13.3 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_3 PF07859.13 ORY50081.1 - 0.065 13.1 0.1 0.086 12.7 0.1 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Sortase PF04203.13 ORY50081.1 - 0.13 12.1 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 Sortase domain Retrotrans_gag PF03732.17 ORY50082.1 - 2.3e-05 24.6 0.3 5.2e-05 23.4 0.1 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein DUF4919 PF16266.5 ORY50082.1 - 0.048 13.6 0.1 0.076 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4919) DUF3524 PF12038.8 ORY50082.1 - 0.077 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3524) RVP_2 PF08284.11 ORY50083.1 - 0.0033 17.2 0.0 0.0035 17.1 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 ORY50083.1 - 0.0049 17.5 0.0 0.007 17.0 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 ORY50083.1 - 0.12 12.9 0.0 0.16 12.6 0.0 1.2 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 ORY50083.1 - 0.14 11.9 0.0 0.16 11.8 0.0 1.0 1 0 0 1 1 1 0 Aspartyl protease Plasmod_MYXSPDY PF07981.11 ORY50084.1 - 3.3 7.8 6.6 82 3.4 0.2 3.5 3 0 0 3 3 3 0 Plasmodium repeat_MYXSPDY AAA_22 PF13401.6 ORY50085.1 - 9.4e-08 32.4 0.0 3.5e-07 30.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 ORY50085.1 - 5.9e-07 29.6 0.0 2.7e-06 27.5 0.0 2.0 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 ORY50085.1 - 3.4e-06 27.5 0.1 1.8e-05 25.2 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 ORY50085.1 - 0.00091 19.7 0.0 0.012 16.0 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CwsA PF10814.8 ORY50085.1 - 0.001 19.3 1.0 0.0053 16.9 0.0 2.2 2 0 0 2 2 2 1 Cell wall synthesis protein CwsA AAA_18 PF13238.6 ORY50085.1 - 0.0024 18.4 0.0 0.0076 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 ORY50085.1 - 0.003 17.4 0.0 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Adeno_IVa2 PF02456.15 ORY50085.1 - 0.0058 15.5 0.0 0.0095 14.8 0.0 1.3 1 0 0 1 1 1 1 Adenovirus IVa2 protein NACHT PF05729.12 ORY50085.1 - 0.018 15.0 0.5 0.31 11.0 0.5 2.7 1 1 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 ORY50085.1 - 0.023 14.4 0.0 0.061 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORY50085.1 - 0.024 14.8 2.0 0.074 13.2 0.0 2.7 3 1 0 3 3 3 0 AAA domain RNA12 PF10443.9 ORY50085.1 - 0.025 13.3 0.0 1.7 7.3 0.0 2.2 2 0 0 2 2 2 0 RNA12 protein ABC_tran PF00005.27 ORY50085.1 - 0.065 13.7 0.2 0.39 11.2 0.0 2.4 3 0 0 3 3 3 0 ABC transporter Saw1 PF11561.8 ORY50086.1 - 0.093 12.3 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Single strand annealing-weakened 1 YqfQ PF14181.6 ORY50087.1 - 0.19 11.9 3.6 0.44 10.7 3.6 1.5 1 0 0 1 1 1 0 YqfQ-like protein SelP_N PF04592.14 ORY50087.1 - 0.43 10.0 22.1 0.018 14.4 15.7 1.9 3 0 0 3 3 3 0 Selenoprotein P, N terminal region Zip PF02535.22 ORY50087.1 - 0.69 9.1 13.1 0.13 11.5 9.7 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter NicO PF03824.16 ORY50087.1 - 1.4 8.2 3.1 2.4 7.5 3.1 1.4 1 0 0 1 1 1 0 High-affinity nickel-transport protein Presenilin PF01080.17 ORY50087.1 - 1.9 7.1 5.4 3.2 6.4 5.4 1.3 1 0 0 1 1 1 0 Presenilin FAM176 PF14851.6 ORY50087.1 - 2.9 7.6 6.0 6.1 6.5 6.0 1.5 1 0 0 1 1 1 0 FAM176 family Innate_immun PF12782.7 ORY50087.1 - 4.6 6.7 15.1 6.6 6.1 15.1 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Cytomega_UL84 PF06284.11 ORY50087.1 - 4.8 5.5 6.5 7.2 4.9 6.5 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein WD40 PF00400.32 ORY50088.1 - 7.1e-16 58.3 0.7 4.5e-05 24.1 0.0 5.2 4 1 1 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY50088.1 - 1.1e-10 41.6 0.0 0.067 13.5 0.0 4.6 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY50088.1 - 0.058 12.0 0.0 0.088 11.4 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 PQQ_3 PF13570.6 ORY50088.1 - 0.14 12.7 0.5 0.52 10.9 0.2 2.2 2 0 0 2 2 2 0 PQQ-like domain SHIPPO-rpt PF07004.12 ORY50090.1 - 4.1e-08 33.8 26.2 0.13 13.3 0.2 7.0 7 1 0 7 7 7 5 Sperm-tail PG-rich repeat Bap31 PF05529.12 ORY50091.1 - 0.03 14.2 0.2 0.031 14.1 0.2 1.1 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region RsbRD_N PF14361.6 ORY50092.1 - 0.13 13.0 0.7 0.4 11.4 0.0 2.1 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain DEAD PF00270.29 ORY50093.1 - 7e-20 71.5 0.0 3.9e-19 69.1 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY50093.1 - 1.5e-09 38.1 0.0 5e-09 36.5 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.6 ORY50093.1 - 0.032 13.6 0.1 0.07 12.5 0.1 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit SNF2_N PF00176.23 ORY50093.1 - 0.056 12.2 0.0 0.12 11.0 0.0 1.5 1 1 0 1 1 1 0 SNF2 family N-terminal domain UTP25 PF06862.12 ORY50093.1 - 0.056 12.2 0.0 0.12 11.1 0.0 1.5 1 1 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 UCH PF00443.29 ORY50094.1 - 1.3e-57 195.3 0.1 1.6e-57 194.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY50094.1 - 3.6e-25 89.2 0.6 8.3e-25 88.0 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 ORY50094.1 - 1.3e-10 41.4 12.3 1.3e-10 41.4 12.3 3.3 4 0 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein SCAMP PF04144.13 ORY50096.1 - 6.3e-45 153.6 7.9 7.5e-45 153.3 7.9 1.0 1 0 0 1 1 1 1 SCAMP family Abhydrolase_1 PF00561.20 ORY50097.1 - 2.5e-27 96.2 0.1 7.7e-26 91.3 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY50097.1 - 5.9e-14 53.2 0.0 1.5e-13 51.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY50097.1 - 2.7e-10 40.0 0.0 3.5e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 ORY50097.1 - 4.9e-09 36.6 0.0 2.5e-08 34.3 0.0 1.8 1 1 1 2 2 2 1 Thioesterase domain PGAP1 PF07819.13 ORY50097.1 - 1.1e-05 25.3 1.2 0.0037 17.0 0.3 2.2 1 1 0 2 2 2 2 PGAP1-like protein Esterase PF00756.20 ORY50097.1 - 0.00052 19.7 0.0 0.00074 19.2 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 ORY50097.1 - 0.00098 19.0 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.14 ORY50097.1 - 0.0014 17.4 0.0 0.0057 15.4 0.0 1.7 2 0 0 2 2 2 1 Ndr family Abhydrolase_5 PF12695.7 ORY50097.1 - 0.0036 17.1 0.0 0.011 15.5 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 ORY50097.1 - 0.0046 16.8 0.0 0.0064 16.4 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Chlorophyllase2 PF12740.7 ORY50097.1 - 0.005 15.8 0.0 0.0074 15.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 ORY50097.1 - 0.0084 15.2 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase PAF-AH_p_II PF03403.13 ORY50097.1 - 0.01 14.4 0.1 0.025 13.1 0.1 1.4 1 1 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DUF676 PF05057.14 ORY50097.1 - 0.011 15.3 0.2 0.023 14.2 0.2 1.5 1 1 0 1 1 1 0 Putative serine esterase (DUF676) DUF2048 PF09752.9 ORY50097.1 - 0.012 14.7 0.0 3.5 6.6 0.0 2.1 2 0 0 2 2 2 0 Abhydrolase domain containing 18 DUF915 PF06028.11 ORY50097.1 - 0.07 12.4 0.1 0.12 11.7 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) BAAT_C PF08840.11 ORY50097.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal eIF-6 PF01912.18 ORY50098.1 - 3.2e-82 274.7 0.7 5.1e-82 274.0 0.3 1.5 2 0 0 2 2 2 1 eIF-6 family PGAP1 PF07819.13 ORY50099.1 - 1.3e-68 231.2 0.3 1.9e-68 230.7 0.3 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.20 ORY50099.1 - 3.9e-05 23.4 0.1 5.9e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 ORY50099.1 - 5e-05 23.3 0.0 7.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 ORY50099.1 - 0.0023 18.6 0.0 0.0034 18.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.12 ORY50099.1 - 0.015 14.8 0.1 0.026 14.1 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 ORY50099.1 - 0.018 14.3 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LCAT PF02450.15 ORY50099.1 - 0.022 14.0 0.0 0.032 13.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase LIDHydrolase PF10230.9 ORY50099.1 - 0.026 14.1 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase ABC_tran PF00005.27 ORY50101.1 - 7.8e-29 100.9 0.0 1.8e-28 99.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 ORY50101.1 - 4.9e-05 23.3 0.0 9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 ORY50101.1 - 0.0022 17.5 0.3 0.072 12.5 0.3 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY50101.1 - 0.0068 16.5 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY50101.1 - 0.0069 16.1 0.2 0.02 14.6 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 ORY50101.1 - 0.018 15.5 0.1 0.048 14.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY50101.1 - 0.019 15.3 0.0 0.04 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 ORY50101.1 - 0.033 14.5 1.8 0.28 11.5 0.2 2.8 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 ORY50101.1 - 0.045 12.8 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_21 PF13304.6 ORY50101.1 - 0.052 13.4 0.8 2.6 7.8 0.3 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 ORY50101.1 - 0.057 13.0 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORY50101.1 - 0.098 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY50101.1 - 0.15 11.8 0.1 0.34 10.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY50101.1 - 0.17 12.3 0.0 0.44 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF87 PF01935.17 ORY50101.1 - 0.2 11.7 0.7 0.49 10.4 0.0 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain DUF829 PF05705.14 ORY50205.1 - 1.3e-24 87.4 0.0 1.6e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) ADH_zinc_N PF00107.26 ORY50208.1 - 2e-13 50.5 0.0 6.5e-13 48.8 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY50208.1 - 5.6e-07 29.4 0.2 0.00025 20.9 0.1 2.4 2 0 0 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 ORY50208.1 - 0.0014 19.7 0.1 0.0058 17.7 0.1 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DUF4350 PF14258.6 ORY50208.1 - 0.02 15.3 0.0 4.7 7.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) ADH_N_2 PF16884.5 ORY50208.1 - 0.15 12.0 0.0 0.72 9.8 0.0 2.0 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase Baculo_LEF-10 PF07206.11 ORY50208.1 - 0.16 12.2 0.1 1.2 9.4 0.0 2.1 2 0 0 2 2 2 0 Baculovirus late expression factor 10 (LEF-10) DUF3368 PF11848.8 ORY50212.1 - 0.057 13.2 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) Peptidase_M24 PF00557.24 ORY50213.1 - 5e-56 189.7 0.2 6.6e-56 189.3 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 ORY50213.1 - 5.9e-35 119.7 0.0 1.1e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain FAM183 PF14886.6 ORY50216.1 - 0.00033 21.4 0.1 0.00052 20.7 0.1 1.7 1 1 0 1 1 1 1 FAM183A and FAM183B related KAR9 PF08580.10 ORY50216.1 - 5.1 5.5 7.7 5.3 5.5 7.7 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Per1 PF04080.13 ORY50220.1 - 5.6 6.7 17.4 0.38 10.5 8.5 2.3 1 1 2 3 3 3 0 Per1-like family zf_CCCH_4 PF18345.1 ORY50224.1 - 0.0008 19.4 3.1 0.0008 19.4 3.1 2.3 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH PF00642.24 ORY50224.1 - 0.00086 19.2 3.7 0.00086 19.2 3.7 2.4 1 1 1 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC_2 PF13696.6 ORY50224.1 - 0.0014 18.4 5.1 0.0014 18.4 5.1 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCCH_4 PF18044.1 ORY50224.1 - 0.024 14.4 2.0 0.024 14.4 2.0 2.2 2 0 0 2 2 2 0 CCCH-type zinc finger Torus PF16131.5 ORY50224.1 - 0.22 12.3 0.1 0.22 12.3 0.1 2.3 3 0 0 3 3 3 0 Torus domain SPX PF03105.19 ORY50224.1 - 1.6 8.6 12.4 77 3.0 12.4 2.2 1 1 0 1 1 1 0 SPX domain zf-CCCH_2 PF14608.6 ORY50224.1 - 2.2 8.9 22.5 0.1 13.1 1.9 3.3 3 1 0 3 3 3 0 RNA-binding, Nab2-type zinc finger TMEM141 PF15110.6 ORY50225.1 - 0.017 15.7 0.3 0.023 15.3 0.3 1.2 1 0 0 1 1 1 0 TMEM141 protein family DUF5389 PF17364.2 ORY50225.1 - 0.12 12.4 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5389) Peptidase_M20 PF01546.28 ORY50226.1 - 1.8e-38 132.3 0.2 2.5e-38 131.8 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 ORY50226.1 - 2.6e-08 33.7 0.0 7e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 ORY50226.1 - 0.0083 15.8 0.0 0.15 11.8 0.0 2.5 2 1 0 2 2 2 1 Peptidase family M28 LRR_8 PF13855.6 ORY50227.1 - 8.3e-19 67.1 18.6 1.1e-08 34.7 5.6 4.7 1 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY50227.1 - 1.3e-15 57.2 26.1 4.2e-06 27.0 1.0 5.2 3 1 3 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY50227.1 - 7.1e-09 35.0 18.6 0.19 12.4 0.1 7.5 8 1 0 8 8 8 3 Leucine Rich Repeat LRR_6 PF13516.6 ORY50227.1 - 0.00042 20.1 10.5 4.6 7.5 0.1 5.2 5 0 0 5 5 5 3 Leucine Rich repeat F-box PF00646.33 ORY50227.1 - 0.014 15.3 0.2 0.034 14.0 0.2 1.7 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 ORY50227.1 - 0.13 12.1 0.6 0.32 10.9 0.6 1.7 1 0 0 1 1 1 0 F-box-like Saf_2TM PF18303.1 ORY50229.1 - 0.12 12.0 4.8 0.89 9.1 0.4 2.5 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain AMP-binding PF00501.28 ORY50230.1 - 1.2e-98 330.5 0.0 1.5e-98 330.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY50230.1 - 0.00029 21.7 0.0 0.0007 20.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RRM_1 PF00076.22 ORY50231.1 - 2.8e-14 52.7 0.2 4.1e-14 52.2 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORY50231.1 - 2.3e-05 24.4 0.1 3.2e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 RNA binding motif FapA PF03961.13 ORY50232.1 - 0.026 13.1 2.9 0.035 12.7 2.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 ORY50232.1 - 0.07 11.0 0.8 0.092 10.7 0.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fmp27_WPPW PF10359.9 ORY50232.1 - 0.41 9.4 5.5 12 4.6 0.0 2.1 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Pkinase PF00069.25 ORY50234.1 - 1.6e-44 152.3 0.0 2e-44 152.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY50234.1 - 2e-15 56.8 0.0 4.5e-15 55.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 ORY50234.1 - 1.3e-06 27.9 0.0 2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY50234.1 - 0.00022 20.2 0.0 0.00028 19.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 ORY50234.1 - 0.0011 18.6 0.1 0.0015 18.2 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 ORY50234.1 - 0.032 14.1 0.0 0.12 12.3 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Cu2_monoox_C PF03712.15 ORY50235.1 - 8.6e-13 48.1 0.6 1.2e-12 47.6 0.6 1.2 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DUF2674 PF10879.8 ORY50235.1 - 0.046 13.3 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2674) PsiF_repeat PF07769.14 ORY50235.1 - 0.062 13.2 0.4 0.096 12.6 0.4 1.3 1 0 0 1 1 1 0 psiF repeat Cu2_monooxygen PF01082.20 ORY50236.1 - 2.9e-30 105.2 0.5 5.5e-30 104.3 0.2 1.6 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 ORY50236.1 - 1.6e-08 34.2 0.0 2.8e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 ORY50237.1 - 2.8e-32 111.7 0.2 5.3e-32 110.8 0.2 1.5 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain Cu2_monoox_C PF03712.15 ORY50237.1 - 1.5e-21 76.6 0.0 2.3e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain DOMON PF03351.17 ORY50237.1 - 2.2e-09 37.6 0.0 5e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 DOMON domain PBP_like_2 PF12849.7 ORY50238.1 - 4.7e-10 39.6 0.1 7.3e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 PBP superfamily domain DUF3611 PF12263.8 ORY50239.1 - 1.3 8.9 6.5 0.94 9.3 1.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3611) DUF3796 PF12676.7 ORY50240.1 - 0.018 15.5 1.2 0.024 15.0 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) DUF3413 PF11893.8 ORY50240.1 - 0.29 10.3 3.5 0.64 9.1 3.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3413) Cu2_monooxygen PF01082.20 ORY50243.1 - 1.8e-32 112.3 0.6 7.8e-31 107.0 0.1 2.6 3 0 0 3 3 3 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain DOMON PF03351.17 ORY50243.1 - 3.2e-18 66.1 0.0 5.7e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 DOMON domain Cu2_monoox_C PF03712.15 ORY50243.1 - 3.8e-07 29.8 0.0 6.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Mit_ribos_Mrp51 PF11709.8 ORY50243.1 - 0.17 11.5 0.1 0.25 10.9 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit Acetyltransf_9 PF13527.7 ORY50244.1 - 3e-09 37.0 0.0 4e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY50244.1 - 0.021 15.2 0.0 0.034 14.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY50244.1 - 0.092 13.0 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Adap_comp_sub PF00928.21 ORY50245.1 - 2.5e-81 272.9 0.1 3.2e-81 272.6 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ORY50245.1 - 0.017 15.0 0.1 0.034 14.1 0.1 1.6 1 0 0 1 1 1 0 Clathrin adaptor complex small chain WW PF00397.26 ORY50247.1 - 8.5e-16 57.7 7.3 2.7e-09 36.9 0.3 2.5 2 0 0 2 2 2 2 WW domain ABC_tran_CTD PF16326.5 ORY50247.1 - 0.016 15.5 0.5 0.047 13.9 0.5 1.9 1 1 0 1 1 1 0 ABC transporter C-terminal domain PI3K_P85_iSH2 PF16454.5 ORY50247.1 - 0.031 13.9 3.5 0.054 13.1 3.2 1.5 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4407 PF14362.6 ORY50247.1 - 0.082 12.2 7.5 0.1 11.9 7.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Osmo_CC PF08946.10 ORY50247.1 - 3.3 8.0 8.2 1.6 9.0 0.3 2.8 3 0 0 3 3 3 0 Osmosensory transporter coiled coil DivIC PF04977.15 ORY50247.1 - 6.5 6.6 11.3 0.56 10.0 0.3 2.8 2 1 0 2 2 2 0 Septum formation initiator Ehbp PF10622.9 ORY50248.1 - 0.008 16.2 0.1 0.0087 16.1 0.1 1.1 1 0 0 1 1 1 1 Energy-converting hydrogenase B subunit P (EhbP) WD40 PF00400.32 ORY50249.1 - 4.8e-56 185.5 18.1 1.4e-08 35.2 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY50249.1 - 3e-16 59.5 0.0 0.00028 21.1 0.0 6.4 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY50249.1 - 1.4e-09 37.4 2.8 0.0015 17.6 0.1 5.2 2 1 4 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 ORY50249.1 - 2.4e-09 37.3 1.4 0.0067 16.3 0.1 3.2 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 ORY50249.1 - 0.00061 18.6 1.6 1 8.0 0.1 3.8 2 1 2 4 4 4 1 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY50249.1 - 0.007 15.7 0.0 0.4 10.0 0.0 2.5 3 0 0 3 3 3 1 WD40-like domain Frtz PF11768.8 ORY50249.1 - 0.022 13.1 0.0 0.084 11.2 0.0 1.7 2 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz DUF2603 PF10788.9 ORY50249.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) Thioredoxin PF00085.20 ORY50250.1 - 1.3e-13 50.8 0.0 1.7e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 ORY50250.1 - 0.011 16.2 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORY50250.1 - 0.033 14.5 0.0 0.11 12.8 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like SpoIIM PF01944.17 ORY50252.1 - 9.9 6.2 14.2 2.1 8.4 10.4 1.8 2 0 0 2 2 2 0 Stage II sporulation protein M Pkinase PF00069.25 ORY50253.1 - 1.2e-56 192.0 0.0 1.6e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY50253.1 - 1.5e-39 135.9 0.0 2.1e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY50253.1 - 0.00013 21.4 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY50253.1 - 0.0004 19.3 0.0 0.0015 17.4 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase DUF1266 PF06889.11 ORY50253.1 - 0.077 13.0 0.1 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) CCDC53 PF10152.9 ORY50253.1 - 0.09 13.2 5.7 0.15 12.5 5.7 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex UPF0492 PF15744.5 ORY50253.1 - 0.18 11.0 6.7 0.23 10.6 6.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein family UPF0492 OSR1_C PF12202.8 ORY50254.1 - 1.7e-09 37.8 0.1 2.6e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain VIT PF08487.10 ORY50254.1 - 0.048 13.9 2.6 0.16 12.2 2.6 1.9 1 1 0 1 1 1 0 Vault protein inter-alpha-trypsin domain RRM_1 PF00076.22 ORY50255.1 - 4.8e-08 32.7 0.0 1.3e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SANT_DAMP1_like PF16282.5 ORY50256.1 - 0.35 11.1 2.4 0.56 10.4 2.4 1.3 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 HMG-CoA_red PF00368.18 ORY50258.1 - 9.1e-95 317.8 0.1 1.4e-94 317.1 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase NAD_binding_4 PF07993.12 ORY50259.1 - 3.4e-68 229.6 0.0 5e-68 229.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 ORY50259.1 - 8.5e-67 225.6 0.0 1.2e-66 225.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 ORY50259.1 - 9.1e-15 54.8 0.1 3.6e-14 52.9 0.1 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site Condensation PF00668.20 ORY50259.1 - 5e-12 45.2 0.0 5.1e-11 41.9 0.0 2.0 1 1 0 1 1 1 1 Condensation domain 3Beta_HSD PF01073.19 ORY50259.1 - 7.5e-09 35.0 0.0 1.8e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 ORY50259.1 - 2.3e-07 30.6 0.0 4.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 ORY50259.1 - 8.8e-07 29.8 0.1 1.8e-05 25.6 0.0 3.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 ORY50259.1 - 0.015 15.2 0.0 0.49 10.3 0.0 2.6 1 1 0 1 1 1 0 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 ORY50259.1 - 0.053 12.9 0.0 0.13 11.7 0.0 1.5 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase ATP_bind_1 PF03029.17 ORY50260.1 - 2.7e-78 263.1 0.2 3.5e-78 262.7 0.2 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 ORY50260.1 - 2.1e-07 31.0 0.0 2e-06 27.9 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY50260.1 - 2.1e-07 30.7 0.1 2e-06 27.5 0.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 ORY50260.1 - 1.9e-05 24.2 0.1 0.0022 17.5 0.0 2.8 3 0 0 3 3 3 1 Ferrous iron transport protein B MeaB PF03308.16 ORY50260.1 - 2.7e-05 23.3 0.1 0.11 11.5 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Ras PF00071.22 ORY50260.1 - 3.4e-05 23.5 0.0 0.0038 16.8 0.0 2.4 2 1 0 2 2 2 1 Ras family G-alpha PF00503.20 ORY50260.1 - 0.00015 21.1 0.0 0.028 13.6 0.0 2.3 2 0 0 2 2 2 1 G-protein alpha subunit AAA_24 PF13479.6 ORY50260.1 - 0.00043 20.1 0.0 0.00076 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 ORY50260.1 - 0.00062 19.7 0.3 2.2 8.2 0.0 3.1 3 1 1 4 4 4 2 RsgA GTPase AAA_22 PF13401.6 ORY50260.1 - 0.00072 19.8 0.0 0.0035 17.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORY50260.1 - 0.0013 18.9 0.0 0.0021 18.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain CLP1_P PF16575.5 ORY50260.1 - 0.0021 17.9 0.0 0.0083 15.9 0.0 1.9 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Roc PF08477.13 ORY50260.1 - 0.0034 17.6 0.0 1 9.6 0.0 2.6 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 ORY50260.1 - 0.0049 16.5 0.0 0.057 13.0 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain DUF87 PF01935.17 ORY50260.1 - 0.0075 16.4 0.2 0.031 14.4 0.0 1.9 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_18 PF13238.6 ORY50260.1 - 0.0079 16.7 1.2 0.35 11.4 0.0 3.2 2 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 ORY50260.1 - 0.0082 16.5 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 ORY50260.1 - 0.0096 15.5 0.2 0.12 11.9 0.1 2.6 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 ORY50260.1 - 0.013 14.9 0.0 3.9 6.9 0.0 3.0 2 1 0 2 2 2 0 ADP-ribosylation factor family Zeta_toxin PF06414.12 ORY50260.1 - 0.014 14.7 0.3 0.057 12.7 0.1 2.0 3 0 0 3 3 3 0 Zeta toxin NACHT PF05729.12 ORY50260.1 - 0.014 15.3 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain CdiI_2 PF18593.1 ORY50260.1 - 0.015 15.9 0.3 0.061 14.0 0.1 2.1 2 0 0 2 2 1 0 CdiI immunity protein AAA_7 PF12775.7 ORY50260.1 - 0.017 14.6 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 ORY50260.1 - 0.029 13.5 0.0 0.065 12.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Ploopntkinase3 PF18751.1 ORY50260.1 - 0.03 14.2 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 PRK PF00485.18 ORY50260.1 - 0.03 14.0 0.1 0.085 12.6 0.0 1.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.6 ORY50260.1 - 0.034 13.8 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 ORY50260.1 - 0.05 13.3 0.1 0.73 9.6 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 ORY50260.1 - 0.058 13.3 0.0 0.67 9.9 0.0 2.2 1 1 0 1 1 1 0 NTPase FtsK_SpoIIIE PF01580.18 ORY50260.1 - 0.079 12.3 0.1 0.2 11.0 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family SRPRB PF09439.10 ORY50260.1 - 0.1 12.0 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit RNA_helicase PF00910.22 ORY50260.1 - 0.11 12.8 0.1 0.35 11.3 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_29 PF13555.6 ORY50260.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.16 ORY50260.1 - 0.16 11.4 0.0 9.2 5.7 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Herpes_BLRF2 PF05812.12 ORY50262.1 - 0.022 14.9 0.3 0.045 13.9 0.3 1.6 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein bZIP_C PF12498.8 ORY50262.1 - 3.8 8.5 4.9 1.4 9.9 0.8 2.3 2 1 0 2 2 2 0 Basic leucine-zipper C terminal DNA_pol_B PF00136.21 ORY50267.1 - 9e-145 482.9 0.3 1.3e-144 482.4 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 ORY50267.1 - 6.2e-84 282.0 0.0 1.2e-83 281.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 ORY50267.1 - 7.2e-18 64.8 7.4 1.3e-17 64.0 7.4 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 ORY50267.1 - 0.002 17.1 0.4 0.0043 16.0 0.4 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.6 ORY50267.1 - 0.047 13.7 0.3 0.4 10.7 0.3 2.3 1 1 0 1 1 1 0 RNase_H superfamily DUF1476 PF07345.11 ORY50267.1 - 0.071 13.5 0.1 1.8 9.0 0.0 2.7 2 0 0 2 2 2 0 ATPase inhibitor subunit zeta DUF5479 PF17575.2 ORY50267.1 - 0.079 13.5 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5479) Acyl-CoA_dh_1 PF00441.24 ORY50269.1 - 8e-40 136.5 1.1 1.2e-39 136.0 1.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY50269.1 - 2.8e-24 85.1 0.0 5.5e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 ORY50269.1 - 3.6e-22 78.3 0.0 8.1e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 ORY50269.1 - 4e-21 75.8 0.0 1.3e-20 74.1 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY50269.1 - 1.3e-07 32.0 0.4 2.1e-07 31.3 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain GCS PF03074.16 ORY50276.1 - 0.22 10.8 0.9 0.24 10.7 0.2 1.4 2 0 0 2 2 2 0 Glutamate-cysteine ligase DUF1754 PF08555.10 ORY50277.1 - 0.011 16.5 2.5 0.011 16.5 2.5 3.1 4 0 0 4 4 4 0 Eukaryotic family of unknown function (DUF1754) eIF3_subunit PF08597.10 ORY50277.1 - 0.89 9.4 14.2 0.65 9.9 0.5 2.6 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DUF3619 PF12279.8 ORY50277.1 - 1.2 9.5 0.0 1.2 9.5 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3619) ubiquitin PF00240.23 ORY50279.1 - 3e-09 36.5 0.0 4.7e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 ORY50279.1 - 0.00036 20.3 0.0 0.0006 19.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 ORY50279.1 - 0.013 15.6 0.0 0.025 14.7 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CAP_N PF01213.19 ORY50280.1 - 1.2 8.6 5.7 1.6 8.2 5.7 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ACCA PF03255.14 ORY50281.1 - 0.06 13.2 6.3 3.3 7.6 0.1 3.0 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ATG16 PF08614.11 ORY50281.1 - 0.32 11.2 9.3 0.053 13.7 2.9 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) FAM76 PF16046.5 ORY50281.1 - 1.5 8.1 12.6 0.31 10.3 7.5 1.9 1 1 1 2 2 2 0 FAM76 protein Spc7 PF08317.11 ORY50281.1 - 2.2 7.1 11.8 16 4.3 11.8 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF848 PF05852.11 ORY50281.1 - 4.6 7.4 8.4 2.8 8.1 4.6 2.4 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Muted PF14942.6 ORY50281.1 - 4.9 7.5 7.8 1.5 9.2 0.2 2.1 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein TMF_DNA_bd PF12329.8 ORY50281.1 - 6.4 6.8 16.3 2 8.5 4.7 3.4 2 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding AA_permease_2 PF13520.6 ORY50282.1 - 2.6e-61 207.7 49.6 3.6e-61 207.3 49.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 ORY50282.1 - 6.1e-20 71.3 44.2 8.8e-20 70.7 44.2 1.1 1 0 0 1 1 1 1 Amino acid permease STb_secrete PF09075.10 ORY50282.1 - 0.13 12.3 1.1 0.29 11.2 1.1 1.6 1 0 0 1 1 1 0 Heat-stable enterotoxin B, secretory Aldedh PF00171.22 ORY50283.1 - 1.8e-167 557.5 0.0 2e-167 557.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 ORY50283.1 - 0.0073 15.8 0.0 0.017 14.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) FH2 PF02181.23 ORY50285.1 - 0.011 14.9 1.2 0.019 14.1 1.2 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain V_ATPase_I PF01496.19 ORY50285.1 - 0.012 13.5 2.5 0.014 13.3 2.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.11 ORY50285.1 - 0.022 15.0 10.0 0.022 15.0 8.2 1.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.11 ORY50285.1 - 0.044 12.7 5.1 0.071 12.0 5.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Med21 PF11221.8 ORY50285.1 - 0.045 14.0 2.3 0.088 13.1 1.8 1.6 1 1 1 2 2 2 0 Subunit 21 of Mediator complex Med9 PF07544.13 ORY50285.1 - 0.054 13.6 4.2 0.11 12.6 0.5 2.5 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Fib_alpha PF08702.10 ORY50285.1 - 0.061 13.5 4.8 0.095 12.9 4.8 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Snapin_Pallidin PF14712.6 ORY50285.1 - 0.062 13.7 3.1 0.16 12.4 3.1 1.7 1 1 0 1 1 1 0 Snapin/Pallidin TSC22 PF01166.18 ORY50285.1 - 0.063 13.6 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family XRCC4 PF06632.12 ORY50285.1 - 0.064 12.1 6.3 0.079 11.8 6.3 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Exonuc_VII_L PF02601.15 ORY50285.1 - 0.1 12.1 6.1 0.12 11.9 6.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF948 PF06103.11 ORY50285.1 - 0.13 12.6 0.2 0.22 11.8 0.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FapA PF03961.13 ORY50285.1 - 0.13 10.8 1.3 0.16 10.6 1.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A BLOC1_2 PF10046.9 ORY50285.1 - 0.17 12.2 1.8 1 9.7 0.4 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NTF2 PF02136.20 ORY50285.1 - 0.19 12.3 1.0 0.5 10.9 1.0 1.8 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain Flg_bb_rod PF00460.20 ORY50285.1 - 0.19 11.7 1.0 9.6 6.3 0.1 2.4 2 0 0 2 2 2 0 Flagella basal body rod protein WXG100 PF06013.12 ORY50285.1 - 0.2 11.9 5.2 0.33 11.2 5.2 1.4 1 0 0 1 1 1 0 Proteins of 100 residues with WXG DUF4677 PF15726.5 ORY50285.1 - 0.28 11.3 2.8 0.59 10.3 0.5 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4677) DUF1664 PF07889.12 ORY50285.1 - 0.33 11.0 2.3 0.55 10.3 2.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FUSC PF04632.12 ORY50285.1 - 0.44 9.0 3.6 0.5 8.8 3.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMPIT PF07851.13 ORY50285.1 - 0.52 9.5 3.1 0.71 9.1 3.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein Tup_N PF08581.10 ORY50285.1 - 0.61 10.4 3.6 1.3 9.4 0.8 2.1 1 1 2 3 3 3 0 Tup N-terminal DUF4140 PF13600.6 ORY50285.1 - 0.75 10.3 4.8 0.83 10.1 0.4 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) USP8_interact PF08941.10 ORY50285.1 - 1.8 8.4 4.9 5 6.9 4.2 1.9 1 1 1 2 2 2 0 USP8 interacting Seryl_tRNA_N PF02403.22 ORY50285.1 - 2.2 8.5 8.5 2.5 8.4 1.8 2.7 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain JHY PF15261.6 ORY50287.1 - 0.1 13.3 0.0 0.13 13.0 0.0 1.3 1 0 0 1 1 1 0 Jhy protein RRM_1 PF00076.22 ORY50288.1 - 7.4e-64 211.5 0.0 7.5e-18 64.1 0.0 4.1 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY50288.1 - 4.7e-05 23.0 0.0 0.41 10.3 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 ORY50288.1 - 0.00011 22.2 1.0 0.46 10.6 0.0 3.6 3 1 0 3 3 3 2 Limkain b1 DbpA PF03880.15 ORY50288.1 - 0.002 18.1 0.3 3.6 7.7 0.0 3.3 3 0 0 3 3 3 2 DbpA RNA binding domain RRM_3 PF08777.11 ORY50288.1 - 0.0023 17.9 0.0 16 5.6 0.0 3.7 4 0 0 4 4 4 1 RNA binding motif RRM_Rrp7 PF17799.1 ORY50288.1 - 0.0067 16.2 0.0 2.7 7.8 0.0 2.4 2 0 0 2 2 2 2 Rrp7 RRM-like N-terminal domain Acetyltransf_7 PF13508.7 ORY50288.1 - 0.03 14.8 0.1 0.69 10.4 0.0 2.9 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY50288.1 - 0.13 12.5 0.0 2.2 8.5 0.0 2.5 2 1 0 2 2 2 0 Acetyltransferase (GNAT) family Sec34 PF04136.15 ORY50289.1 - 2.5e-05 24.2 9.5 0.044 13.7 0.5 2.9 1 1 2 3 3 2 2 Sec34-like family GIT_CC PF16559.5 ORY50289.1 - 9.2e-05 22.2 12.7 0.00019 21.2 0.5 3.4 2 1 1 3 3 3 1 GIT coiled-coil Rho guanine nucleotide exchange factor Tropomyosin_1 PF12718.7 ORY50289.1 - 0.00015 22.0 7.1 0.041 14.0 3.8 2.3 1 1 1 2 2 2 2 Tropomyosin like BLOC1_2 PF10046.9 ORY50289.1 - 0.0012 19.1 3.7 0.0012 19.1 3.7 3.3 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4686 PF15742.5 ORY50289.1 - 0.0016 17.7 9.4 0.067 12.3 4.7 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4686) KASH_CCD PF14662.6 ORY50289.1 - 0.0028 17.5 11.1 0.052 13.4 4.9 2.4 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH DivIC PF04977.15 ORY50289.1 - 0.0074 16.0 4.4 0.19 11.5 0.1 3.4 3 0 0 3 3 3 1 Septum formation initiator ADIP PF11559.8 ORY50289.1 - 0.011 15.9 14.5 1 9.5 7.7 3.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding APG17 PF04108.12 ORY50289.1 - 0.017 14.3 10.6 0.034 13.2 10.6 1.6 1 1 0 1 1 1 0 Autophagy protein Apg17 DUF4201 PF13870.6 ORY50289.1 - 0.018 14.8 0.2 0.018 14.8 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) ZapB PF06005.12 ORY50289.1 - 0.019 15.4 8.2 0.71 10.4 2.1 3.0 1 1 1 2 2 2 0 Cell division protein ZapB V_ATPase_I PF01496.19 ORY50289.1 - 0.028 12.4 8.1 0.047 11.6 8.1 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Uso1_p115_C PF04871.13 ORY50289.1 - 0.029 14.8 5.8 0.34 11.3 0.9 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Cep57_CLD_2 PF14197.6 ORY50289.1 - 0.034 14.2 4.4 5.1 7.3 0.0 3.4 4 0 0 4 4 2 0 Centrosome localisation domain of PPC89 GAS PF13851.6 ORY50289.1 - 0.036 13.4 8.1 0.28 10.5 8.1 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 ORY50289.1 - 0.037 14.0 15.4 0.33 11.0 0.5 3.3 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Lzipper-MIP1 PF14389.6 ORY50289.1 - 0.041 14.2 1.2 0.19 12.0 0.2 2.6 2 1 1 3 3 2 0 Leucine-zipper of ternary complex factor MIP1 JAKMIP_CC3 PF16034.5 ORY50289.1 - 0.042 13.8 5.0 0.15 12.0 2.9 2.0 1 1 1 2 2 2 0 JAKMIP CC3 domain Prefoldin_2 PF01920.20 ORY50289.1 - 0.051 13.5 5.8 1.7 8.7 0.2 3.6 3 1 1 4 4 3 0 Prefoldin subunit Spectrin PF00435.21 ORY50289.1 - 0.054 14.0 3.8 0.12 12.9 1.0 2.3 1 1 1 2 2 2 0 Spectrin repeat Jnk-SapK_ap_N PF09744.9 ORY50289.1 - 0.057 13.6 8.5 0.1 12.8 1.5 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 YabA PF06156.13 ORY50289.1 - 0.059 14.0 11.4 1.9 9.2 1.9 3.8 2 1 1 3 3 3 0 Initiation control protein YabA Rootletin PF15035.6 ORY50289.1 - 0.062 13.3 5.3 2 8.4 1.6 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Phage_Gp17 PF17549.2 ORY50289.1 - 0.064 13.3 2.9 2.5 8.2 0.1 3.0 1 1 1 3 3 3 0 Gene Product 17 CLZ PF16526.5 ORY50289.1 - 0.069 13.5 11.2 0.54 10.6 0.2 4.6 4 1 2 6 6 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4472 PF14739.6 ORY50289.1 - 0.07 13.9 7.6 0.31 11.8 1.3 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4472) PI3K_P85_iSH2 PF16454.5 ORY50289.1 - 0.14 11.7 8.9 1.9 8.1 0.1 3.1 1 1 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain bZIP_1 PF00170.21 ORY50289.1 - 0.17 12.0 10.3 1.8 8.8 0.3 3.5 3 0 0 3 3 3 0 bZIP transcription factor ABC_tran_CTD PF16326.5 ORY50289.1 - 0.2 11.9 1.9 4.2 7.7 0.1 2.9 2 1 1 3 3 2 0 ABC transporter C-terminal domain WXG100 PF06013.12 ORY50289.1 - 0.29 11.4 5.5 0.78 10.0 0.1 3.3 3 1 0 3 3 3 0 Proteins of 100 residues with WXG FlaC_arch PF05377.11 ORY50289.1 - 0.32 11.4 11.7 0.32 11.4 0.2 3.8 3 1 3 6 6 5 0 Flagella accessory protein C (FlaC) TPR_MLP1_2 PF07926.12 ORY50289.1 - 0.33 11.0 9.7 13 5.9 0.3 3.0 1 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 ORY50289.1 - 0.43 11.1 4.1 0.51 10.9 0.8 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region NPV_P10 PF05531.12 ORY50289.1 - 0.55 10.7 10.4 0.18 12.3 1.5 3.2 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein UPF0184 PF03670.13 ORY50289.1 - 0.59 10.6 6.3 22 5.5 0.5 3.4 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0184) CENP-F_leu_zip PF10473.9 ORY50289.1 - 0.66 10.0 11.6 21 5.1 10.7 3.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 ORY50289.1 - 0.68 9.5 7.3 0.88 9.1 0.2 3.0 1 1 1 3 3 3 0 Intermediate filament protein UPF0242 PF06785.11 ORY50289.1 - 0.71 9.9 8.9 12 5.9 8.9 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Syntaxin PF00804.25 ORY50289.1 - 0.81 9.3 8.1 1.4 8.5 0.6 2.5 1 1 0 2 2 2 0 Syntaxin Syntaxin-6_N PF09177.11 ORY50289.1 - 1.1 9.9 13.1 1.1e+02 3.4 9.4 3.5 2 1 0 2 2 1 0 Syntaxin 6, N-terminal ATG16 PF08614.11 ORY50289.1 - 1.2 9.4 11.8 5.2 7.3 0.6 2.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 ORY50289.1 - 1.5 9.5 5.5 4.1 8.1 0.5 3.1 1 1 2 3 3 3 0 SlyX YlqD PF11068.8 ORY50289.1 - 1.8 9.0 7.3 7.3 7.0 1.2 2.4 1 1 1 2 2 2 0 YlqD protein Spc24 PF08286.11 ORY50289.1 - 1.8 8.8 12.8 3.1 8.1 1.2 3.3 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 Phage_GP20 PF06810.11 ORY50289.1 - 2.2 8.1 9.3 0.38 10.6 2.2 2.6 1 1 1 2 2 2 0 Phage minor structural protein GP20 JIP_LZII PF16471.5 ORY50289.1 - 2.2 8.5 8.2 8.7 6.6 1.3 3.2 2 2 1 3 3 3 0 JNK-interacting protein leucine zipper II Swi5 PF07061.11 ORY50289.1 - 2.3 8.4 7.1 3.5 7.8 0.3 3.2 2 1 1 3 3 3 0 Swi5 TSC22 PF01166.18 ORY50289.1 - 2.4 8.6 10.0 13 6.2 0.2 3.9 2 1 2 4 4 4 0 TSC-22/dip/bun family DUF724 PF05266.14 ORY50289.1 - 2.5 7.9 9.7 1.4 8.7 1.7 2.6 2 1 1 3 3 2 0 Protein of unknown function (DUF724) Fez1 PF06818.15 ORY50289.1 - 3 8.3 8.2 20 5.6 8.2 2.1 1 1 0 1 1 1 0 Fez1 DUF16 PF01519.16 ORY50289.1 - 4.1 7.9 9.6 2.3 8.8 1.0 2.9 1 1 2 3 3 3 0 Protein of unknown function DUF16 DASH_Dam1 PF08653.10 ORY50289.1 - 5.4 6.9 10.0 35 4.3 0.1 4.1 4 1 1 5 5 4 0 DASH complex subunit Dam1 Syntaxin_2 PF14523.6 ORY50289.1 - 6.4 7.2 16.5 27 5.2 9.7 3.3 1 1 2 3 3 3 0 Syntaxin-like protein bZIP_2 PF07716.15 ORY50289.1 - 6.6 6.9 8.5 7.7 6.7 0.2 3.5 3 2 0 3 3 2 0 Basic region leucine zipper DUF4795 PF16043.5 ORY50289.1 - 8.3 6.0 11.5 2.3e+02 1.2 11.6 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) KxDL PF10241.9 ORY50290.1 - 0.025 14.8 5.2 0.047 14.0 5.2 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein DUF4201 PF13870.6 ORY50290.1 - 0.06 13.1 7.1 0.085 12.6 7.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) GAS PF13851.6 ORY50290.1 - 0.097 12.0 9.2 0.13 11.6 9.2 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding COG2 PF06148.11 ORY50290.1 - 0.11 12.6 1.2 0.16 12.0 1.2 1.3 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF16 PF01519.16 ORY50290.1 - 0.18 12.3 4.6 0.33 11.5 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF1664 PF07889.12 ORY50290.1 - 0.27 11.3 3.1 0.51 10.4 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) CENP-H PF05837.12 ORY50290.1 - 0.43 11.0 7.3 1.1 9.7 7.3 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ZapB PF06005.12 ORY50290.1 - 0.7 10.4 11.0 0.45 11.0 9.1 1.7 1 1 0 1 1 1 0 Cell division protein ZapB TMPIT PF07851.13 ORY50290.1 - 1.2 8.3 4.1 1.6 7.9 3.6 1.4 2 0 0 2 2 2 0 TMPIT-like protein XkdW PF09636.10 ORY50290.1 - 4.2 7.5 7.1 1.2 9.2 0.2 2.2 1 1 1 2 2 2 0 XkdW protein EF-hand_7 PF13499.6 ORY50291.1 - 6.4e-17 61.8 0.1 2.3e-12 47.2 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 ORY50291.1 - 6.7e-17 59.7 1.5 2.5e-06 26.6 0.1 3.8 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 ORY50291.1 - 9.9e-15 53.1 0.0 0.0002 21.0 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 ORY50291.1 - 3.3e-09 36.4 0.7 9.5e-05 22.2 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 ORY50291.1 - 5.9e-09 35.0 0.9 0.0003 20.2 0.1 3.6 3 1 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 ORY50291.1 - 0.0003 21.1 0.0 0.0012 19.1 0.0 1.9 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 ORY50291.1 - 0.088 13.2 0.0 1.2 9.6 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain EF-hand_13 PF17958.1 ORY50291.1 - 0.1 12.4 0.0 21 5.0 0.0 2.5 1 1 1 2 2 2 0 EF-hand domain RRM_1 PF00076.22 ORY50292.1 - 1.8e-29 101.3 0.4 6.6e-11 41.9 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY50292.1 - 5e-10 39.1 0.0 0.00049 19.9 0.0 3.2 3 0 0 3 3 3 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 ORY50292.1 - 8.2e-05 22.5 0.0 7.3 6.7 0.0 3.4 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.11 ORY50292.1 - 0.001 18.9 0.0 0.039 13.8 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF1866) DUF4523 PF15023.6 ORY50292.1 - 0.0019 18.0 0.0 0.099 12.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4523) RRM_3 PF08777.11 ORY50292.1 - 0.0021 18.1 0.0 0.12 12.4 0.0 3.1 4 0 0 4 4 4 1 RNA binding motif RRM_7 PF16367.5 ORY50292.1 - 0.0043 17.1 0.0 4.5 7.4 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif HcyBio PF01837.16 ORY50292.1 - 0.055 12.3 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 Homocysteine biosynthesis enzyme, sulfur-incorporation PHM7_cyt PF14703.6 ORY50292.1 - 0.24 11.6 0.0 12 6.1 0.0 2.3 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter CAP_N PF01213.19 ORY50293.1 - 1.1e-106 356.9 0.2 1.4e-106 356.6 0.2 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 ORY50293.1 - 5.1e-60 201.6 2.8 6.9e-60 201.2 2.8 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 ORY50293.1 - 3.1e-05 23.7 2.9 5.6e-05 22.9 2.9 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C Trm112p PF03966.16 ORY50297.1 - 7.5e-13 48.9 0.0 8.8e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein Tenui_NCP PF04876.12 ORY50297.1 - 0.025 14.2 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein MMR_HSR1 PF01926.23 ORY50298.1 - 7.7e-08 32.4 1.4 0.00017 21.7 0.5 2.7 2 1 1 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY50298.1 - 0.00016 21.6 0.5 0.054 13.4 0.1 3.1 1 1 1 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 ORY50298.1 - 0.0013 18.3 0.2 0.014 14.9 0.2 2.5 2 1 1 3 3 3 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORY50298.1 - 0.0032 17.6 1.8 0.76 9.8 0.3 3.1 2 1 1 3 3 3 2 Dynamin family IIGP PF05049.13 ORY50298.1 - 0.0033 16.6 0.0 0.06 12.4 0.0 2.0 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_18 PF13238.6 ORY50298.1 - 0.11 13.1 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 ORY50298.1 - 0.18 11.3 0.0 0.84 9.1 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family AIG1 PF04548.16 ORY50298.1 - 0.36 10.1 2.6 2.9 7.2 0.4 2.9 2 2 1 3 3 3 0 AIG1 family ENTH PF01417.20 ORY50299.1 - 1.3e-23 83.4 0.1 7e-23 81.0 0.0 2.2 2 1 0 2 2 2 1 ENTH domain ANTH PF07651.16 ORY50299.1 - 0.0033 16.5 0.0 0.0033 16.5 0.0 2.0 2 0 0 2 2 2 1 ANTH domain DUF5072 PF16807.5 ORY50299.1 - 0.16 12.0 0.0 0.34 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5072) CSRNP_N PF16019.5 ORY50299.1 - 5 7.0 8.0 0.35 10.8 2.7 1.7 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus DUF4587 PF15248.6 ORY50301.1 - 0.0059 17.4 3.8 0.011 16.5 2.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4587) DUF2790 PF10976.8 ORY50302.1 - 0.035 14.1 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2790) Ferric_reduct PF01794.19 ORY50303.1 - 3.9e-11 43.1 8.5 3.9e-11 43.1 8.5 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 ORY50303.1 - 4.5e-08 33.1 0.0 1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 ORY50303.1 - 0.00053 20.1 0.1 0.00098 19.3 0.1 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Fungal_trans PF04082.18 ORY50304.1 - 0.00016 20.8 1.3 0.063 12.3 0.1 2.8 2 0 0 2 2 2 2 Fungal specific transcription factor domain FAM70 PF14967.6 ORY50305.1 - 0.067 12.7 0.9 0.094 12.2 0.9 1.1 1 0 0 1 1 1 0 FAM70 protein RasGEF PF00617.19 ORY50306.1 - 4.2e-51 173.7 0.1 1.4e-50 172.0 0.1 1.9 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY50306.1 - 3.7e-15 56.0 2.4 2.2e-14 53.6 0.5 3.0 2 0 0 2 2 2 1 RasGEF N-terminal motif DHC PF09626.10 ORY50306.1 - 0.061 14.2 0.1 0.3 12.0 0.1 2.2 2 0 0 2 2 2 0 Dihaem cytochrome c DnaJ PF00226.31 ORY50308.1 - 4.9e-13 49.0 0.5 6.1e-13 48.7 0.5 1.1 1 0 0 1 1 1 1 DnaJ domain DUF3744 PF12558.8 ORY50308.1 - 0.039 14.7 0.1 0.048 14.4 0.1 1.2 1 0 0 1 1 1 0 ATP-binding cassette cobalt transporter TMEM135_C_rich PF15982.5 ORY50309.1 - 9.4e-05 23.0 0.1 0.00012 22.7 0.1 1.1 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 Tim17 PF02466.19 ORY50310.1 - 3.1e-05 24.3 0.0 5.7e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family FOP_dimer PF09398.10 ORY50310.1 - 0.12 12.6 0.0 0.33 11.2 0.0 1.8 1 1 0 1 1 1 0 FOP N terminal dimerisation domain Diphthamide_syn PF01866.17 ORY50311.1 - 1.8e-102 342.8 0.0 2.7e-102 342.3 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein RAP1 PF07218.11 ORY50312.1 - 6.5 4.9 6.4 7.3 4.7 6.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Abhydrolase_1 PF00561.20 ORY50313.1 - 1.3e-05 25.0 0.0 2.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY50313.1 - 2.6e-05 24.9 0.1 4.6e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY50313.1 - 0.00015 21.1 0.0 0.00022 20.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 OATP PF03137.20 ORY50313.1 - 0.029 12.7 0.9 0.046 12.0 0.9 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family zf-CHCC PF10276.9 ORY50313.1 - 0.032 14.3 0.2 0.068 13.2 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger domain Thioesterase PF00975.20 ORY50313.1 - 0.17 12.0 0.0 0.25 11.4 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DHHC PF01529.20 ORY50313.1 - 5.3 7.1 7.9 15 5.7 2.5 2.4 1 1 1 2 2 2 0 DHHC palmitoyltransferase Pox_A14 PF05767.12 ORY50313.1 - 8.1 6.7 7.6 8.7 6.6 1.7 3.0 2 1 0 2 2 2 0 Poxvirus virion envelope protein A14 Tetraspanin PF00335.20 ORY50314.1 - 2e-10 40.8 1.0 5.1e-08 32.9 0.6 2.1 2 0 0 2 2 2 2 Tetraspanin family FliD_N PF02465.18 ORY50315.1 - 0.012 16.3 0.7 0.012 16.3 0.7 3.0 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus HAP1_N PF04849.13 ORY50315.1 - 0.014 14.6 0.1 0.014 14.6 0.1 1.6 2 0 0 2 2 2 0 HAP1 N-terminal conserved region bZIP_1 PF00170.21 ORY50315.1 - 0.019 15.1 3.9 0.044 13.9 1.2 2.4 1 1 1 2 2 2 0 bZIP transcription factor Shugoshin_N PF07558.11 ORY50315.1 - 0.045 13.6 0.2 0.13 12.2 0.2 1.7 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region SPX PF03105.19 ORY50315.1 - 0.1 12.5 4.6 0.17 11.8 4.6 1.3 1 0 0 1 1 1 0 SPX domain Tropomyosin PF00261.20 ORY50315.1 - 0.12 11.8 1.5 0.2 11.0 1.5 1.3 1 0 0 1 1 1 0 Tropomyosin CLZ PF16526.5 ORY50315.1 - 0.14 12.5 1.7 0.39 11.1 1.7 1.8 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Glyco_hydro_18 PF00704.28 ORY50317.1 - 2.7e-15 56.9 1.2 7.5e-15 55.5 1.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 GST_C PF00043.25 ORY50318.1 - 1e-07 32.0 0.0 1.7e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY50318.1 - 1.7e-07 31.2 0.0 2.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY50318.1 - 2.3e-06 27.7 0.1 6.7e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY50318.1 - 0.0005 20.3 0.0 0.00081 19.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 ORY50318.1 - 0.0038 17.5 0.0 0.0074 16.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Abhydrolase_3 PF07859.13 ORY50319.1 - 2e-20 73.5 0.0 3.1e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY50319.1 - 9.2e-11 41.2 0.0 3.6e-10 39.3 0.0 1.8 1 1 0 1 1 1 1 Steryl acetyl hydrolase DOPA_dioxygen PF08883.11 ORY50320.1 - 9.8e-30 102.9 0.1 1.1e-29 102.7 0.1 1.0 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family DOPA_dioxygen PF08883.11 ORY50321.1 - 1.6e-20 73.3 0.4 7.2e-18 64.7 0.4 2.0 1 1 0 1 1 1 1 Dopa 4,5-dioxygenase family DOPA_dioxygen PF08883.11 ORY50322.1 - 1.2e-32 112.2 0.0 1.7e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Phage_Cox PF10743.9 ORY50323.1 - 0.063 13.4 0.3 0.17 12.0 0.1 1.8 2 0 0 2 2 2 0 Regulatory phage protein cox ResIII PF04851.15 ORY50324.1 - 1.1e-23 84.1 0.0 1.4e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY50324.1 - 2.6e-15 56.6 0.0 3.4e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 ORY50324.1 - 2.3e-06 27.4 0.0 3.5e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_11 PF13086.6 ORY50324.1 - 6.4e-05 22.9 0.1 0.0084 15.9 0.0 2.1 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 ORY50324.1 - 0.0003 20.6 0.0 0.00048 19.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY50324.1 - 0.0023 18.2 0.1 0.024 14.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 ORY50324.1 - 0.0031 16.8 0.0 0.0043 16.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.23 ORY50324.1 - 0.0041 15.9 0.0 0.0059 15.4 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain TBCC PF07986.12 ORY50324.1 - 0.011 15.4 0.2 5.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Tubulin binding cofactor C DUF3860 PF12976.7 ORY50324.1 - 0.13 12.3 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) DUF1804 PF08822.11 ORY50324.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) BTB PF00651.31 ORY50325.1 - 0.00021 21.5 0.1 0.00039 20.6 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain SDA1 PF05285.12 ORY50325.1 - 0.0031 17.0 3.3 0.0031 17.0 3.3 3.0 3 0 0 3 3 3 1 SDA1 CNDH2_C PF16858.5 ORY50325.1 - 0.14 12.0 8.4 1.3 8.8 0.6 2.6 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term 4F5 PF04419.14 ORY50326.1 - 2.4e-09 37.9 11.0 2.4e-09 37.9 11.0 2.4 2 1 0 2 2 2 1 4F5 protein family DUF4355 PF14265.6 ORY50326.1 - 0.014 15.6 6.0 0.018 15.3 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) COX2_TM PF02790.15 ORY50328.1 - 0.023 14.9 0.0 0.034 14.3 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain ECSCR PF15820.5 ORY50328.1 - 0.09 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Nitrate_red_del PF02613.15 ORY50329.1 - 0.26 11.3 0.0 0.39 10.7 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase delta subunit PWWP PF00855.17 ORY50330.1 - 7.2e-19 68.0 0.2 7.2e-19 68.0 0.2 2.3 2 1 0 2 2 2 1 PWWP domain Med26 PF08711.11 ORY50330.1 - 6.7e-06 26.0 0.3 2.7e-05 24.1 0.3 2.1 1 0 0 1 1 1 1 TFIIS helical bundle-like domain SF1-HH PF16275.5 ORY50331.1 - 3.7e-35 120.7 0.2 6.6e-35 119.9 0.2 1.4 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 ORY50331.1 - 3.3e-09 36.4 9.7 0.00027 20.9 3.0 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 ORY50331.1 - 5.2e-08 32.6 0.3 1.1e-07 31.5 0.3 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 ORY50331.1 - 3.8e-05 23.5 5.5 0.0011 18.8 1.8 2.4 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 ORY50331.1 - 0.0063 16.2 6.0 0.61 9.9 0.8 2.6 2 0 0 2 2 2 2 Zinc knuckle Prim_Zn_Ribbon PF08273.12 ORY50331.1 - 0.046 14.0 1.9 0.12 12.6 1.9 1.7 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase zf-CHY PF05495.12 ORY50331.1 - 0.18 12.3 2.2 0.3 11.6 0.5 2.2 2 1 1 3 3 3 0 CHY zinc finger PHD_4 PF16866.5 ORY50331.1 - 0.42 10.7 3.5 0.78 9.9 1.9 2.1 2 0 0 2 2 2 0 PHD-finger DEC-1_N PF04625.13 ORY50331.1 - 0.75 8.7 7.8 1.1 8.1 7.8 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Alk_phosphatase PF00245.20 ORY50332.1 - 9.4e-49 166.5 0.2 1.6e-47 162.4 0.2 2.5 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 ORY50332.1 - 0.0068 15.8 0.0 0.026 13.9 0.0 1.9 2 0 0 2 2 2 1 Metalloenzyme superfamily Med3 PF11593.8 ORY50334.1 - 0.87 8.7 24.0 1.5 7.9 24.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NUDE_C PF04880.13 ORY50334.1 - 3.3 8.1 10.4 6.5 7.2 10.4 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region FSA_C PF10479.9 ORY50334.1 - 4.7 5.2 7.2 7 4.6 7.2 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Velvet PF11754.8 ORY50335.1 - 6.6e-46 157.3 0.1 9.3e-30 104.4 0.2 2.0 1 1 1 2 2 2 2 Velvet factor SH3_9 PF14604.6 ORY50336.1 - 7.9e-12 44.9 0.2 1.3e-11 44.1 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY50336.1 - 1.7e-08 34.0 1.2 3.7e-08 32.9 1.2 1.6 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY50336.1 - 1.2e-06 28.1 0.0 2.2e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain CENP-B_dimeris PF09026.10 ORY50336.1 - 0.0058 17.0 0.7 0.011 16.1 0.7 1.5 1 0 0 1 1 1 1 Centromere protein B dimerisation domain PBP1_TM PF14812.6 ORY50336.1 - 0.6 10.5 3.5 1.1 9.7 3.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RhoGEF PF00621.20 ORY50337.1 - 4.1e-25 89.1 0.0 4.6e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 RhoGEF domain PX PF00787.24 ORY50338.1 - 5.3e-10 39.3 0.1 7e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 PX domain DUF3528 PF12045.8 ORY50338.1 - 0.047 14.3 0.1 0.069 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3528) AHD PF17793.1 ORY50338.1 - 0.88 9.4 4.3 13 5.7 0.1 2.6 3 0 0 3 3 3 0 ANC1 homology domain (AHD) Rtf2 PF04641.12 ORY50339.1 - 1.8e-50 171.8 0.1 2.1e-50 171.5 0.1 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.6 ORY50339.1 - 0.41 10.7 2.6 1.4 9.0 0.1 2.3 2 0 0 2 2 2 0 RING-type zinc-finger FH2 PF02181.23 ORY50340.1 - 1.5e-66 225.0 15.1 9.3e-51 173.1 0.1 3.4 2 1 1 3 3 3 2 Formin Homology 2 Domain Drf_FH3 PF06367.16 ORY50340.1 - 4.5e-24 85.2 0.1 1.2e-23 83.8 0.1 1.7 1 0 0 1 1 1 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 ORY50340.1 - 7.4e-18 64.8 2.0 2.2e-17 63.3 2.0 1.8 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain DUF525 PF04379.14 ORY50340.1 - 5.7e-09 36.1 0.0 1.3e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 ApaG domain U-box PF04564.15 ORY50341.1 - 7.5e-26 90.1 0.0 1.6e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 ORY50341.1 - 3.3e-09 36.2 0.3 0.062 13.2 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat CHIP_TPR_N PF18391.1 ORY50341.1 - 1.9e-08 35.0 5.1 3.9e-08 33.9 5.1 1.6 1 0 0 1 1 1 1 CHIP N-terminal tetratricopeptide repeat domain TPR_2 PF07719.17 ORY50341.1 - 7.7e-08 31.9 2.8 0.0047 16.9 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 ORY50341.1 - 2.2e-06 27.2 0.0 0.0037 16.9 0.0 2.6 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 ORY50341.1 - 0.0012 19.4 0.1 0.0062 17.2 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY50341.1 - 0.023 15.0 0.2 38 4.7 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 ORY50341.1 - 0.037 14.2 0.0 0.18 12.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 ORY50341.1 - 0.16 12.4 0.4 4.6 7.8 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat MutS_V PF00488.21 ORY50345.1 - 3.2e-67 226.2 0.1 1.3e-66 224.2 0.0 2.1 3 0 0 3 3 3 1 MutS domain V MutS_III PF05192.18 ORY50345.1 - 3.2e-31 109.1 0.1 5.5e-31 108.3 0.1 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 ORY50345.1 - 1.9e-29 102.2 0.0 4.4e-29 101.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 ORY50345.1 - 7.1e-11 42.5 0.0 2.1e-10 41.0 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 ORY50345.1 - 0.02 15.2 0.0 0.059 13.7 0.0 1.8 1 0 0 1 1 1 0 MutS family domain IV TMF_TATA_bd PF12325.8 ORY50345.1 - 0.46 10.7 2.1 4.9 7.4 0.3 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Herpes_DNAp_acc PF04929.12 ORY50346.1 - 1.2 8.1 5.1 1.5 7.8 5.1 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor RRM_1 PF00076.22 ORY50350.1 - 3.5e-24 84.4 0.0 3e-12 46.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 ORY50350.1 - 0.0053 16.8 0.6 0.077 13.1 0.3 2.7 2 1 1 3 3 3 1 RNA binding motif Chalcone_3 PF16036.5 ORY50350.1 - 0.11 12.6 0.5 0.33 11.1 0.0 2.0 2 0 0 2 2 2 0 Chalcone isomerase-like UBN_AB PF14075.6 ORY50357.1 - 1.5e-06 28.1 0.6 1.5e-06 28.1 0.6 3.6 3 1 1 4 4 4 2 Ubinuclein conserved middle domain BUD22 PF09073.10 ORY50357.1 - 0.0012 18.3 33.9 0.0031 16.9 33.9 1.7 1 0 0 1 1 1 1 BUD22 DUF4736 PF15883.5 ORY50357.1 - 0.22 11.2 0.5 0.62 9.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4736) SET PF00856.28 ORY50360.1 - 5.4e-10 39.9 0.0 8e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 SET domain GTP_EFTU PF00009.27 ORY50361.1 - 2.1e-43 148.1 0.0 1.1e-42 145.8 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 ORY50361.1 - 5e-16 58.5 0.0 1.4e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 ORY50361.1 - 2.2e-06 27.7 0.0 4.9e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 ORY50361.1 - 2.5e-05 24.6 0.0 5.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 ORY50361.1 - 0.0014 18.4 0.0 0.0072 16.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV DUF5044 PF16447.5 ORY50362.1 - 0.014 15.2 0.3 0.084 12.7 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5044) PRP1_N PF06424.12 ORY50364.1 - 8.3e-54 182.0 6.7 1.8e-53 181.0 6.7 1.6 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 ORY50364.1 - 5.9e-27 92.0 33.3 0.00021 21.8 0.0 14.5 5 3 11 16 16 14 7 Tetratricopeptide repeat TPR_19 PF14559.6 ORY50364.1 - 7.6e-19 68.0 24.1 7.7e-06 26.3 0.2 9.3 6 2 4 10 10 9 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY50364.1 - 1.4e-12 46.6 7.1 0.013 15.5 0.1 9.0 11 0 0 11 11 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY50364.1 - 3.4e-10 39.3 2.0 3.2 8.2 0.0 7.7 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY50364.1 - 1.9e-09 38.0 23.5 2.5e-07 31.2 0.0 7.3 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY50364.1 - 1.5e-08 34.8 3.9 0.14 12.5 0.2 6.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY50364.1 - 6.5e-06 25.7 0.1 0.081 12.8 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY50364.1 - 0.00017 21.7 1.0 24 5.6 0.1 6.6 8 1 1 9 9 6 0 Tetratricopeptide repeat NARP1 PF12569.8 ORY50364.1 - 0.00027 20.0 11.9 0.0007 18.6 0.0 4.3 3 1 1 4 4 4 2 NMDA receptor-regulated protein 1 FAT PF02259.23 ORY50364.1 - 0.0035 16.6 5.6 0.18 11.0 2.7 3.6 2 2 0 2 2 2 1 FAT domain ANAPC3 PF12895.7 ORY50364.1 - 0.0047 17.1 1.3 2 8.7 0.1 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 ORY50364.1 - 0.0093 15.6 2.9 1.2 8.8 0.0 4.8 6 1 0 6 6 6 1 TPR repeat Fis1_TPR_C PF14853.6 ORY50364.1 - 0.018 15.1 0.9 6 7.0 0.0 4.2 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF3808 PF10300.9 ORY50364.1 - 0.034 12.9 2.7 3.1 6.4 0.2 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3808) Tcf25 PF04910.14 ORY50364.1 - 0.046 12.8 0.6 1.5 7.8 0.1 2.9 1 1 1 2 2 2 0 Transcriptional repressor TCF25 PriA_C PF18074.1 ORY50364.1 - 0.077 13.8 0.1 0.37 11.6 0.1 2.3 1 0 0 1 1 1 0 Primosomal protein N C-terminal domain Suf PF05843.14 ORY50364.1 - 0.093 12.7 3.0 10 6.0 0.0 3.7 5 0 0 5 5 5 0 Suppressor of forked protein (Suf) Wzy_C_2 PF11846.8 ORY50364.1 - 0.12 12.2 1.8 69 3.3 0.0 4.5 4 0 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal TPR_6 PF13174.6 ORY50364.1 - 0.14 12.9 28.5 0.2 12.3 0.0 9.8 13 0 0 13 13 8 0 Tetratricopeptide repeat PTS_IIA PF02255.16 ORY50364.1 - 0.15 12.1 2.6 1.7 8.7 0.6 3.4 2 1 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Sigma70_ner PF04546.13 ORY50364.1 - 0.16 11.9 6.6 0.38 10.6 6.6 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region TPR_7 PF13176.6 ORY50364.1 - 0.24 11.5 1.8 4.5 7.5 0.0 3.8 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY50364.1 - 0.32 10.9 3.4 1.9 8.5 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat HA2 PF04408.23 ORY50365.1 - 2.1e-22 79.4 0.0 4.4e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 ORY50365.1 - 2.4e-14 53.5 0.0 4.9e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 ORY50365.1 - 1.3e-11 44.6 0.1 2.6e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY50365.1 - 8.9e-09 35.7 0.0 3.7e-08 33.7 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 ORY50365.1 - 5.1e-08 33.3 0.1 1.4e-07 31.9 0.1 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 ORY50365.1 - 0.00037 20.6 0.1 0.0035 17.4 0.1 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 ORY50365.1 - 0.0014 18.4 0.1 0.0025 17.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 ORY50365.1 - 0.0016 17.6 0.0 0.0033 16.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.14 ORY50365.1 - 0.0018 18.3 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain ABC_tran PF00005.27 ORY50365.1 - 0.0026 18.3 0.2 0.22 12.0 0.2 2.5 1 1 0 1 1 1 1 ABC transporter AAA_19 PF13245.6 ORY50365.1 - 0.006 16.9 0.1 0.013 15.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 ORY50365.1 - 0.014 14.7 0.0 0.041 13.2 0.0 1.8 2 0 0 2 2 2 0 KaiC SRP54 PF00448.22 ORY50365.1 - 0.015 14.9 0.7 0.06 13.0 0.7 2.0 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 ORY50365.1 - 0.02 14.9 0.3 4.2 7.4 0.1 2.5 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.9 ORY50365.1 - 0.025 13.9 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 ORY50365.1 - 0.046 13.6 0.0 0.095 12.5 0.0 1.6 1 0 0 1 1 1 0 Helicase Herpes_ori_bp PF02399.15 ORY50365.1 - 0.081 11.0 0.1 0.14 10.2 0.1 1.3 1 0 0 1 1 1 0 Origin of replication binding protein PARG_cat PF05028.14 ORY50367.1 - 3.7e-115 384.8 0.0 4.8e-115 384.5 0.0 1.0 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) 2OG-FeII_Oxy_3 PF13640.6 ORY50368.1 - 4.1e-17 62.8 0.0 6.4e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 ORY50368.1 - 0.00013 22.6 0.0 0.00022 21.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GLE1 PF07817.13 ORY50371.1 - 0.018 14.3 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 GLE1-like protein RRM_1 PF00076.22 ORY50373.1 - 5.5e-32 109.4 0.0 9.1e-12 44.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY50373.1 - 1.7e-12 47.0 0.0 6.3e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 ORY50373.1 - 1.9e-05 24.6 0.0 0.43 10.7 0.0 3.6 3 1 0 3 3 3 2 Limkain b1 BRAP2 PF07576.12 ORY50373.1 - 0.079 13.2 0.0 1.3 9.3 0.0 2.2 2 0 0 2 2 2 0 BRCA1-associated protein 2 MutS_III PF05192.18 ORY50375.1 - 3.4e-25 89.4 0.1 4.9e-25 88.9 0.1 1.3 1 0 0 1 1 1 1 MutS domain III Methyltransf_19 PF04672.12 ORY50375.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl methyltransferase UBN_AB PF14075.6 ORY50377.1 - 6.2e-15 55.5 3.4 1.7e-09 37.7 0.1 2.2 1 1 1 2 2 2 2 Ubinuclein conserved middle domain DUF2972 PF11186.8 ORY50377.1 - 0.057 13.3 0.5 0.088 12.7 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) NADH_dh_m_C1 PF15088.6 ORY50378.1 - 0.024 14.2 2.6 0.11 12.2 0.1 2.6 3 0 0 3 3 3 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial DEAD PF00270.29 ORY50380.1 - 4.4e-22 78.7 0.0 5.9e-20 71.7 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY50380.1 - 8.9e-22 77.5 0.0 6.5e-19 68.3 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.10 ORY50380.1 - 2.3e-16 59.6 0.0 5.6e-16 58.3 0.0 1.7 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 ORY50380.1 - 2.8e-16 60.0 7.2 2.8e-16 60.0 7.2 2.4 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 ORY50380.1 - 0.0066 16.5 0.0 0.031 14.3 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit NUDIX PF00293.28 ORY50381.1 - 5.6e-27 94.4 0.0 7.1e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain PAP_central PF04928.17 ORY50382.1 - 1.9e-83 279.2 0.0 2.5e-83 278.9 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 ORY50382.1 - 8.6e-36 123.1 0.0 2.6e-35 121.6 0.0 1.8 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 ORY50382.1 - 3.3e-07 30.5 2.4 4.2e-07 30.2 0.7 2.1 2 0 0 2 2 2 1 Nucleotidyltransferase domain RRM_1 PF00076.22 ORY50382.1 - 0.00095 18.9 0.0 0.0036 17.1 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY50382.1 - 0.02 15.0 0.1 0.1 12.7 0.1 2.1 2 0 0 2 2 2 0 RNA recognition motif AAA PF00004.29 ORY50385.1 - 3.9e-10 40.3 0.0 1.2e-09 38.7 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY50385.1 - 1.6e-09 38.4 0.2 3.7e-08 33.9 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 ORY50385.1 - 7.7e-09 35.9 0.0 2.6e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 ORY50385.1 - 4.3e-05 23.5 0.0 0.00011 22.2 0.0 1.8 1 1 0 1 1 1 1 NACHT domain DUF2075 PF09848.9 ORY50385.1 - 0.0007 18.9 0.0 0.0012 18.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) TniB PF05621.11 ORY50385.1 - 0.001 18.5 0.1 0.026 13.9 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein Sigma54_activat PF00158.26 ORY50385.1 - 0.0036 17.0 0.0 0.11 12.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.6 ORY50385.1 - 0.0038 17.6 0.0 0.011 16.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 ORY50385.1 - 0.0064 16.3 0.1 0.044 13.5 0.0 2.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 ORY50385.1 - 0.027 14.5 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit TIP49 PF06068.13 ORY50385.1 - 0.039 13.2 0.1 0.067 12.4 0.1 1.4 1 1 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 ORY50385.1 - 0.047 13.6 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 ORY50385.1 - 0.065 12.8 0.1 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 ORY50385.1 - 0.07 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MeaB PF03308.16 ORY50385.1 - 0.087 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 ORY50385.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF5388 PF17363.2 ORY50385.1 - 0.11 12.7 0.1 8 6.8 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5388) NB-ARC PF00931.22 ORY50385.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF3638 PF12340.8 ORY50386.1 - 1.2e-56 191.6 0.1 2.3e-56 190.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 ORY50386.1 - 6e-11 41.5 0.3 1.3e-10 40.5 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) PI3K_P85_iSH2 PF16454.5 ORY50386.1 - 0.066 12.8 3.8 0.13 11.8 0.1 2.5 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain CHD5 PF04420.14 ORY50386.1 - 0.95 9.3 4.8 3 7.7 4.8 1.8 1 0 0 1 1 1 0 CHD5-like protein Siva PF05458.12 ORY50391.1 - 0.024 14.3 8.8 0.024 14.3 8.8 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) PRIMA1 PF16101.5 ORY50392.1 - 5.6 7.0 7.7 9.7 6.3 7.7 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 FAD_binding_3 PF01494.19 ORY50393.1 - 1.2e-23 83.9 0.0 2.5e-19 69.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ORY50393.1 - 9.1e-10 38.2 0.0 0.0015 17.8 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY50393.1 - 8.8e-06 25.5 0.1 0.052 13.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY50393.1 - 4.8e-05 22.8 0.1 0.053 12.8 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY50393.1 - 6.6e-05 23.1 0.1 0.00021 21.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 ORY50393.1 - 7.5e-05 21.6 0.0 0.12 11.0 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 ORY50393.1 - 0.00011 22.7 0.0 0.27 11.8 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY50393.1 - 0.0014 17.5 0.1 0.88 8.3 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase Lycopene_cycl PF05834.12 ORY50393.1 - 0.0028 16.8 0.2 0.017 14.2 0.2 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 ORY50393.1 - 0.0069 16.4 0.0 2.8 7.9 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 ORY50393.1 - 0.028 13.5 0.0 0.047 12.8 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A IlvN PF07991.12 ORY50393.1 - 0.04 13.5 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FAD_binding_2 PF00890.24 ORY50393.1 - 0.047 12.8 0.1 0.097 11.7 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Amino_oxidase PF01593.24 ORY50393.1 - 0.095 12.0 0.0 0.56 9.4 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase DHDPS PF00701.22 ORY50393.1 - 0.12 11.0 0.1 1.1 7.8 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate synthetase family UDPG_MGDP_dh_N PF03721.14 ORY50393.1 - 0.35 10.4 1.2 0.42 10.2 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF4525 PF15027.6 ORY50394.1 - 0.17 11.6 0.5 0.27 11.0 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4525) DctQ PF04290.12 ORY50395.1 - 0.18 11.7 4.9 0.24 11.3 0.2 2.2 1 1 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component CBFD_NFYB_HMF PF00808.23 ORY50396.1 - 6.1e-06 26.4 1.2 6.3e-06 26.4 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Barttin PF15462.6 ORY50396.1 - 0.017 14.9 1.2 0.021 14.6 1.2 1.1 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) Ribosomal_60s PF00428.19 ORY50396.1 - 2.4 8.8 17.0 6 7.5 17.0 1.9 1 1 0 1 1 1 0 60s Acidic ribosomal protein DSPc PF00782.20 ORY50397.1 - 1e-22 80.4 0.0 1.2e-19 70.4 0.0 2.1 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 ORY50397.1 - 0.001 19.3 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 ORY50397.1 - 0.0082 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Spc7 PF08317.11 ORY50399.1 - 0.0021 17.0 29.2 0.0052 15.7 15.5 2.4 1 1 1 2 2 2 2 Spc7 kinetochore protein TRCF PF03461.15 ORY50399.1 - 0.0089 16.4 0.9 0.0089 16.4 0.9 2.8 3 1 0 3 3 3 1 TRCF domain DASH_Dam1 PF08653.10 ORY50399.1 - 0.23 11.3 2.7 3.4 7.5 0.0 3.6 3 1 1 4 4 4 0 DASH complex subunit Dam1 DUF4253 PF14062.6 ORY50399.1 - 0.47 10.7 2.1 1.4 9.1 0.4 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4253) bZIP_1 PF00170.21 ORY50399.1 - 0.49 10.5 13.8 0.96 9.6 0.2 5.1 4 2 1 5 5 5 0 bZIP transcription factor FemAB_like PF04339.12 ORY50399.1 - 1.2 8.1 8.9 0.51 9.4 3.1 2.0 1 1 1 2 2 2 0 Peptidogalycan biosysnthesis/recognition AhpC-TSA PF00578.21 ORY50399.1 - 1.3 9.0 3.8 6.1 6.8 0.2 3.0 1 1 1 2 2 2 0 AhpC/TSA family SKA2 PF16740.5 ORY50399.1 - 2.1 8.2 22.0 1.6 8.6 5.0 3.5 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 HALZ PF02183.18 ORY50399.1 - 8.5 6.7 15.2 4 7.7 0.4 4.3 5 0 0 5 5 5 0 Homeobox associated leucine zipper HMMR_N PF15905.5 ORY50399.1 - 8.5 5.7 33.5 0.54 9.7 4.7 3.1 1 1 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Mcp5_PH PF12814.7 ORY50401.1 - 3.9e-09 36.7 0.0 5.2e-08 33.0 0.0 2.3 1 1 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology BLOC1_2 PF10046.9 ORY50402.1 - 0.029 14.6 0.3 0.031 14.5 0.3 1.0 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GldM_N PF12081.8 ORY50402.1 - 0.03 14.4 0.0 0.032 14.3 0.0 1.0 1 0 0 1 1 1 0 GldM N-terminal domain Thump_like PF18096.1 ORY50402.1 - 0.075 13.0 0.0 0.08 12.9 0.0 1.1 1 0 0 1 1 1 0 THUMP domain-like FAM60A PF15396.6 ORY50403.1 - 5.8 6.9 11.8 6 6.8 2.7 2.3 2 0 0 2 2 2 0 Protein Family FAM60A MIF4G PF02854.19 ORY50405.1 - 2.2e-51 174.5 11.2 3.2e-51 174.0 8.3 2.3 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.17 ORY50405.1 - 2.6e-13 49.9 2.9 7e-13 48.5 0.1 2.8 3 0 0 3 3 3 1 MA3 domain Glyco_hydro_18 PF00704.28 ORY50406.1 - 0.00033 20.5 0.1 0.00041 20.2 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Spc7 PF08317.11 ORY50407.1 - 0.0026 16.7 49.6 0.0065 15.4 6.4 4.4 1 1 2 4 4 4 2 Spc7 kinetochore protein HALZ PF02183.18 ORY50407.1 - 0.026 14.7 16.5 2.3 8.5 0.3 5.6 5 0 0 5 5 5 0 Homeobox associated leucine zipper AhpC-TSA PF00578.21 ORY50407.1 - 0.055 13.4 7.4 1.2 9.1 0.1 4.0 2 2 2 4 4 4 0 AhpC/TSA family TRCF PF03461.15 ORY50407.1 - 0.23 11.9 6.7 0.1 13.0 0.8 3.4 4 0 0 4 4 4 0 TRCF domain DUF4253 PF14062.6 ORY50407.1 - 0.49 10.6 3.7 6.6 7.0 0.1 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF4253) DASH_Dam1 PF08653.10 ORY50407.1 - 2.9 7.8 6.4 62 3.5 0.0 4.7 5 0 0 5 5 5 0 DASH complex subunit Dam1 Glyco_hydro_18 PF00704.28 ORY50408.1 - 2.3e-12 47.3 0.2 4.7e-12 46.3 0.2 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 ORY50409.1 - 4.5e-10 39.8 0.7 9.3e-10 38.7 0.7 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Abhydrolase_3 PF07859.13 ORY50410.1 - 8.7e-15 55.1 3.0 1.4e-12 48.0 3.0 3.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY50410.1 - 6.7e-14 51.5 0.0 1.3e-11 44.0 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase DUF1822 PF08852.11 ORY50411.1 - 0.028 13.5 0.0 0.036 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) WD40 PF00400.32 ORY50412.1 - 1.5e-10 41.5 4.3 0.012 16.4 0.0 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY50412.1 - 0.00016 21.9 0.0 6.1 7.2 0.0 4.0 4 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Spindle_Spc25 PF08234.12 ORY50413.1 - 1.3e-21 76.6 0.2 2.3e-21 75.8 0.2 1.4 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Spc7 PF08317.11 ORY50413.1 - 0.26 10.1 8.1 0.53 9.1 8.1 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 ORY50413.1 - 0.33 10.0 6.7 0.63 9.1 6.6 1.3 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 ORY50413.1 - 0.52 10.8 14.8 0.64 10.5 12.7 2.2 2 1 0 2 2 2 0 Apg6 coiled-coil region Glyco_hydro_18 PF00704.28 ORY50414.1 - 1.3e-14 54.7 0.1 1.8e-14 54.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_19 PF03427.13 ORY50414.1 - 0.026 14.5 5.6 0.065 13.2 5.6 1.6 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) Abhydrolase_3 PF07859.13 ORY50415.1 - 7.4e-22 78.2 0.0 1.1e-21 77.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 ORY50415.1 - 3.5e-15 55.9 0.0 1.4e-14 53.9 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family CBS PF00571.28 ORY50416.1 - 2.1e-12 47.3 4.7 1.4e-05 25.4 0.0 4.6 4 2 0 4 4 4 3 CBS domain PCO_ADO PF07847.12 ORY50417.1 - 6.4e-31 107.4 2.5 1e-30 106.7 0.5 2.1 2 1 0 2 2 2 1 PCO_ADO NINJA_B PF16136.5 ORY50417.1 - 2.8 8.3 4.7 1.3 9.4 2.2 1.7 2 0 0 2 2 2 0 Putative nuclear localisation signal Asp PF00026.23 ORY50419.1 - 1.4e-49 169.3 4.0 6.4e-42 144.1 1.6 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY50419.1 - 6.6e-11 42.8 0.4 6.6e-11 42.8 0.4 2.6 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal Cadherin-like PF12733.7 ORY50419.1 - 0.23 12.0 0.8 0.55 10.8 0.8 1.6 1 0 0 1 1 1 0 Cadherin-like beta sandwich domain LPMO_10 PF03067.15 ORY50420.1 - 1.9e-05 25.4 0.2 1.9e-05 25.4 0.2 2.7 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Ras PF00071.22 ORY50421.1 - 2.1e-50 170.5 0.0 2.6e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY50421.1 - 5.6e-20 71.7 0.0 8.1e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY50421.1 - 2.1e-08 33.8 0.0 2.9e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY50421.1 - 0.054 13.6 0.0 0.076 13.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 ORY50421.1 - 0.083 12.2 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region LRR_4 PF12799.7 ORY50422.1 - 2e-12 47.1 5.0 6.5e-05 23.2 0.2 4.3 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORY50422.1 - 6e-09 35.6 0.7 4.4e-06 26.3 0.1 2.6 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 ORY50422.1 - 1.8e-06 27.6 7.8 0.024 14.4 0.0 3.8 3 1 1 5 5 5 3 Leucine rich repeat LRR_1 PF00560.33 ORY50422.1 - 0.051 14.1 1.7 69 4.6 0.0 4.4 3 1 0 3 3 3 0 Leucine Rich Repeat Imm32 PF15566.6 ORY50422.1 - 0.21 11.4 0.9 0.54 10.1 0.1 2.1 2 0 0 2 2 2 0 Immunity protein 32 LRR_4 PF12799.7 ORY50423.1 - 1.9e-14 53.6 7.6 1.8e-05 25.0 0.1 3.8 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORY50423.1 - 1.7e-11 43.9 0.1 3.2e-08 33.3 0.0 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 ORY50423.1 - 1e-07 31.6 8.3 0.0025 17.5 0.9 3.8 3 2 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 ORY50423.1 - 0.0039 17.5 2.2 51 5.0 0.0 4.5 3 1 0 3 3 3 0 Leucine Rich Repeat DUF1118 PF06549.12 ORY50423.1 - 0.099 13.0 0.2 3.4 8.0 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1118) RuBisCO_large PF00016.20 ORY50423.1 - 0.1 11.8 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain PC-Esterase PF13839.6 ORY50424.1 - 1e-17 64.9 0.5 3.4e-17 63.1 0.5 1.8 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p PC-Esterase PF13839.6 ORY50425.1 - 6.8e-20 72.0 0.1 2.2e-19 70.3 0.1 1.8 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Halo_GVPC PF05465.13 ORY50426.1 - 0.36 11.1 9.1 1.6 9.0 7.8 2.0 1 1 1 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat Dioxygenase_C PF00775.21 ORY50427.1 - 5.2e-11 42.3 1.0 2.2e-06 27.3 0.0 2.5 1 1 1 2 2 2 2 Dioxygenase Asp PF00026.23 ORY50428.1 - 3.5e-44 151.5 1.2 1.6e-37 129.6 0.1 2.1 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY50428.1 - 2.1e-05 24.8 4.1 0.01 16.1 0.1 3.7 3 1 1 4 4 4 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY50428.1 - 0.00033 20.5 0.0 0.00073 19.3 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 ORY50428.1 - 0.013 16.1 0.4 4.2 8.1 0.1 3.3 2 1 1 3 3 3 0 Aspartyl protease DEC-1_N PF04625.13 ORY50428.1 - 3.3 6.6 13.3 5.8 5.8 13.3 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Alginate_lyase2 PF08787.11 ORY50431.1 - 4.3e-25 88.9 0.4 5.6e-25 88.6 0.4 1.2 1 0 0 1 1 1 1 Alginate lyase Tyrosinase PF00264.20 ORY50432.1 - 2.2e-05 24.9 11.2 0.00016 22.1 11.1 2.3 1 1 0 1 1 1 1 Common central domain of tyrosinase Mucin PF01456.17 ORY50432.1 - 2.3 8.2 35.6 0.77 9.7 27.8 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein Dicty_REP PF05086.12 ORY50432.1 - 3 5.7 5.4 4 5.3 5.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RRM_1 PF00076.22 ORY50434.1 - 3e-14 52.6 0.0 5.8e-10 38.9 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 ORY50434.1 - 0.059 13.5 0.0 0.2 11.8 0.0 1.7 2 0 0 2 2 2 0 Limkain b1 PK PF00224.21 ORY50436.1 - 1.7e-94 316.6 1.8 5e-56 190.1 0.9 2.5 2 1 0 2 2 2 2 Pyruvate kinase, barrel domain PK_C PF02887.16 ORY50436.1 - 1.4e-05 25.3 0.0 5.9e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 ORY50436.1 - 0.044 12.9 0.5 0.096 11.8 0.2 1.7 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family RRM_1 PF00076.22 ORY50437.1 - 6.8e-18 64.3 0.1 4e-17 61.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY50437.1 - 0.00085 19.4 0.0 0.0025 17.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif DUF1314 PF07013.11 ORY50437.1 - 0.19 11.6 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) Casc1 PF12366.8 ORY50437.1 - 1.1 8.8 9.5 1.8 8.0 9.5 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 GREB1 PF15782.5 ORY50437.1 - 4.1 4.4 9.9 5.1 4.1 9.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2367 PF10164.9 ORY50438.1 - 1.8e-10 41.2 1.0 2.2e-10 41.0 1.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) Ribosomal_L22e PF01776.17 ORY50439.1 - 1.8e-35 121.6 0.1 2.2e-35 121.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Adaptin_N PF01602.20 ORY50440.1 - 6.5e-110 368.2 0.0 7.9e-110 367.9 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ORY50440.1 - 6.7e-09 36.0 3.9 6.5e-07 29.5 0.1 3.9 2 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORY50440.1 - 4e-06 27.1 1.1 0.8 10.1 0.0 4.2 3 1 1 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 ORY50440.1 - 0.0009 19.7 2.2 6.7 7.3 0.0 5.3 6 1 0 6 6 6 2 HEAT-like repeat HEAT PF02985.22 ORY50440.1 - 0.0018 18.4 2.4 5.5 7.5 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat Mito_carr PF00153.27 ORY50441.1 - 1.9e-18 66.1 0.5 3.7e-12 46.0 0.1 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein CAP PF00188.26 ORY50442.1 - 6.8e-17 62.5 2.1 4.6e-14 53.3 0.4 2.3 2 0 0 2 2 2 2 Cysteine-rich secretory protein family Creatinase_N_2 PF16189.5 ORY50443.1 - 0.13 12.3 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Creatinase/Prolidase N-terminal domain MRC1 PF09444.10 ORY50443.1 - 0.22 12.0 4.5 2.9 8.4 1.8 2.2 2 0 0 2 2 2 0 MRC1-like domain Glyco_hydro_76 PF03663.14 ORY50445.1 - 1.4e-39 136.7 12.9 2e-39 136.2 12.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 zf_CCCH_4 PF18345.1 ORY50446.1 - 0.004 17.2 1.8 0.004 17.2 1.8 2.7 3 0 0 3 3 3 1 Zinc finger domain DDHD PF02862.17 ORY50447.1 - 2.5e-22 80.1 0.4 3.3e-21 76.5 0.4 2.2 1 1 0 1 1 1 1 DDHD domain DUF3761 PF12587.8 ORY50449.1 - 0.066 13.7 2.3 4.1 7.9 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3761) zf-CCCH PF00642.24 ORY50450.1 - 0.014 15.3 0.3 0.014 15.3 0.3 6.0 6 0 0 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MBOAT PF03062.19 ORY50451.1 - 2.1e-32 112.8 5.6 2.5e-32 112.6 5.6 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Dala_Dala_lig_C PF07478.13 ORY50452.1 - 0.084 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus KAR9 PF08580.10 ORY50454.1 - 0.096 11.2 9.8 0.12 10.9 9.8 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 zf-HIT PF04438.16 ORY50454.1 - 2.3 8.2 8.2 1.5 8.7 0.3 2.6 1 1 1 2 2 2 0 HIT zinc finger zf_CCCH_4 PF18345.1 ORY50455.1 - 0.00015 21.7 3.7 0.00015 21.7 3.7 4.2 4 0 0 4 4 4 1 Zinc finger domain zf-CCCH PF00642.24 ORY50455.1 - 0.00049 19.9 0.7 0.00049 19.9 0.7 4.7 5 0 0 5 5 5 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY50456.1 - 0.0012 18.9 4.7 0.0012 18.9 4.7 3.7 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH PF00642.24 ORY50456.1 - 0.004 17.0 1.0 0.004 17.0 1.0 4.8 5 0 0 5 5 5 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC_2 PF13696.6 ORY50456.1 - 0.068 13.0 0.9 0.068 13.0 0.9 3.5 4 0 0 4 4 4 0 Zinc knuckle zf-CCCH_4 PF18044.1 ORY50456.1 - 0.22 11.3 23.3 0.28 11.0 3.0 3.8 3 0 0 3 3 3 0 CCCH-type zinc finger USP7_ICP0_bdg PF12436.8 ORY50457.1 - 8.8e-13 48.1 0.0 2.4e-12 46.7 0.0 1.6 1 1 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 Sugarporin_N PF11471.8 ORY50457.1 - 0.068 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension SlyX PF04102.12 ORY50457.1 - 0.23 12.1 5.3 0.2 12.3 2.9 2.1 2 0 0 2 2 2 0 SlyX ATG16 PF08614.11 ORY50457.1 - 0.24 11.6 6.5 0.41 10.8 6.5 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) zf-C4pol PF14260.6 ORY50458.1 - 0.074 13.5 2.4 5.5 7.5 0.4 2.7 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DivIC PF04977.15 ORY50458.1 - 0.13 12.1 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 Septum formation initiator Acetyltransf_1 PF00583.25 ORY50459.1 - 1.2e-10 41.6 0.0 1.5e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY50459.1 - 5.9e-06 26.2 0.0 8.6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY50459.1 - 1.8e-05 25.1 0.0 2.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORY50459.1 - 2.1e-05 25.2 0.0 2.7e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY50459.1 - 3e-05 23.9 0.1 5e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 ORY50460.1 - 1.4e-10 41.4 0.1 1.7e-10 41.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY50460.1 - 5.7e-08 32.8 0.1 9.5e-08 32.0 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY50460.1 - 3.7e-07 30.0 0.1 5.6e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 ORY50460.1 - 1.1e-06 28.9 0.3 1.6e-06 28.4 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 ORY50460.1 - 1.3e-05 25.9 0.0 1.7e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY50460.1 - 0.003 17.7 0.0 0.0048 17.0 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 ORY50460.1 - 0.0039 16.9 0.0 0.0055 16.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Clat_adaptor_s PF01217.20 ORY50461.1 - 2.4e-53 179.9 1.9 2.9e-53 179.6 1.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3587 PF12132.8 ORY50461.1 - 0.041 13.3 0.1 0.058 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3587) DUF1460 PF07313.12 ORY50461.1 - 0.068 12.5 0.1 0.086 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) Clat_adaptor_s PF01217.20 ORY50462.1 - 1.1e-52 177.7 3.2 1.3e-52 177.5 3.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3587 PF12132.8 ORY50462.1 - 0.0092 15.4 0.4 0.012 15.0 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3587) Cas_DxTHG PF09455.10 ORY50462.1 - 0.055 13.0 1.1 0.065 12.8 1.1 1.1 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Cons_hypoth698 PF03601.14 ORY50463.1 - 2.9e-48 164.3 14.9 1.1e-23 83.7 0.1 2.0 2 0 0 2 2 2 2 Conserved hypothetical protein 698 DUF1689 PF07954.11 ORY50463.1 - 0.098 13.1 0.1 7.3 7.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) ABC_tran PF00005.27 ORY50464.1 - 2.3e-58 196.6 0.9 4.7e-33 114.6 0.1 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORY50464.1 - 7e-44 150.5 40.7 2.9e-24 86.2 20.9 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ORY50464.1 - 6.8e-11 42.0 10.0 0.0032 16.9 0.6 4.4 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY50464.1 - 1.5e-10 40.6 2.4 1.3e-05 24.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY50464.1 - 1.8e-07 31.2 0.5 0.021 14.9 0.1 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 ORY50464.1 - 7e-07 29.3 4.9 0.029 14.2 0.0 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ORY50464.1 - 2e-06 28.5 4.5 0.021 15.3 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 ORY50464.1 - 3.4e-06 27.5 0.1 0.052 13.9 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 ORY50464.1 - 0.00015 22.1 0.6 0.57 10.5 0.0 3.4 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.12 ORY50464.1 - 0.00016 21.0 2.3 0.18 11.0 0.1 2.3 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 ORY50464.1 - 0.00033 20.6 4.6 0.098 12.6 0.7 3.0 3 0 0 3 3 2 2 RsgA GTPase FtsK_SpoIIIE PF01580.18 ORY50464.1 - 0.00056 19.3 0.3 0.69 9.2 0.2 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF87 PF01935.17 ORY50464.1 - 0.00079 19.6 8.2 0.047 13.8 0.1 2.8 3 0 0 3 3 2 2 Helicase HerA, central domain T2SSE PF00437.20 ORY50464.1 - 0.00095 18.3 2.2 0.45 9.5 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF815 PF05673.13 ORY50464.1 - 0.0011 18.2 0.1 0.51 9.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_7 PF12775.7 ORY50464.1 - 0.0013 18.3 0.8 1.5 8.3 0.2 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region Dynamin_N PF00350.23 ORY50464.1 - 0.0016 18.5 2.6 0.23 11.5 1.0 3.1 2 0 0 2 2 2 1 Dynamin family AAA_30 PF13604.6 ORY50464.1 - 0.0018 18.0 6.7 0.58 9.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain TrwB_AAD_bind PF10412.9 ORY50464.1 - 0.0021 17.0 1.6 0.49 9.3 0.2 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain Roc PF08477.13 ORY50464.1 - 0.0023 18.2 0.8 2.8 8.2 0.1 3.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ploopntkinase3 PF18751.1 ORY50464.1 - 0.004 17.1 0.7 2.1 8.2 0.2 2.6 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 NB-ARC PF00931.22 ORY50464.1 - 0.0042 16.3 1.0 0.93 8.6 0.1 2.7 3 0 0 3 3 3 1 NB-ARC domain MeaB PF03308.16 ORY50464.1 - 0.0067 15.4 2.8 0.65 8.9 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ATP-synt_ab PF00006.25 ORY50464.1 - 0.008 15.9 0.1 3.7 7.2 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain NACHT PF05729.12 ORY50464.1 - 0.024 14.6 4.4 2.4 8.0 0.7 2.8 3 0 0 3 3 2 0 NACHT domain RNA_helicase PF00910.22 ORY50464.1 - 0.031 14.6 0.1 8.2 6.9 0.0 2.8 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 ORY50464.1 - 0.042 13.6 2.9 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.19 ORY50464.1 - 0.067 12.8 1.7 7.4 6.1 0.1 2.9 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_ATPase PF09818.9 ORY50464.1 - 0.068 12.0 1.1 0.62 8.8 0.2 2.6 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_18 PF13238.6 ORY50464.1 - 0.11 13.0 0.3 20 5.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ORY50464.1 - 0.16 11.5 2.6 1.6 8.2 0.9 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 ORY50464.1 - 0.21 11.6 1.2 3.3 7.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 ORY50464.1 - 0.22 11.2 1.9 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 ORY50464.1 - 0.67 10.1 1.9 42 4.3 1.1 2.5 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 ORY50464.1 - 0.68 9.6 3.2 3.5 7.3 0.1 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_15 PF13175.6 ORY50464.1 - 1.5 8.4 10.4 2 8.1 0.2 2.9 3 1 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.27 ORY50465.1 - 3.4e-51 173.4 0.2 1.5e-28 100.0 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 ORY50465.1 - 4.1e-32 111.9 40.4 6.2e-24 85.1 19.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ORY50465.1 - 1.7e-13 50.5 4.5 0.00083 18.8 0.0 4.3 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY50465.1 - 1.4e-06 28.3 0.9 0.056 13.5 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY50465.1 - 1.7e-06 27.7 4.8 0.02 14.6 0.1 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 ORY50465.1 - 2.5e-05 24.9 0.8 0.06 13.8 0.2 2.8 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 ORY50465.1 - 3.5e-05 23.8 0.1 0.62 9.8 0.1 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORY50465.1 - 6.8e-05 22.8 0.3 0.068 13.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 ORY50465.1 - 0.00044 20.4 4.5 0.035 14.2 0.5 2.5 2 0 0 2 2 2 2 Helicase HerA, central domain NB-ARC PF00931.22 ORY50465.1 - 0.00093 18.4 0.3 1.2 8.2 0.1 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_15 PF13175.6 ORY50465.1 - 0.0026 17.6 0.1 0.4 10.3 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 ORY50465.1 - 0.0032 16.6 0.1 0.61 9.1 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Dynamin_N PF00350.23 ORY50465.1 - 0.0036 17.4 3.3 0.92 9.5 0.1 3.3 3 0 0 3 3 3 1 Dynamin family AAA_16 PF13191.6 ORY50465.1 - 0.0068 16.8 0.1 0.4 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 ORY50465.1 - 0.0072 15.7 0.0 1.2 8.4 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.6 ORY50465.1 - 0.0085 15.7 0.2 3 7.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 ORY50465.1 - 0.019 14.7 1.6 2.3 7.9 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 ORY50465.1 - 0.021 15.1 2.2 6.8 7.0 0.6 3.2 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ORY50465.1 - 0.023 13.9 0.2 3.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.17 ORY50465.1 - 0.033 14.0 1.1 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DEAD PF00270.29 ORY50465.1 - 0.085 12.6 1.4 0.55 10.0 0.3 2.5 2 1 0 2 2 2 0 DEAD/DEAH box helicase MeaB PF03308.16 ORY50465.1 - 0.09 11.7 0.3 3.6 6.5 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 ORY50465.1 - 0.091 12.3 2.5 5.1 6.6 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_7 PF12775.7 ORY50465.1 - 0.1 12.1 0.2 12 5.4 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Ploopntkinase3 PF18751.1 ORY50465.1 - 0.12 12.3 0.2 6.6 6.6 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 ORY50465.1 - 0.17 12.3 0.2 20 5.6 0.0 3.1 3 0 0 3 3 3 0 RNA helicase TrwB_AAD_bind PF10412.9 ORY50465.1 - 0.21 10.5 1.6 7.6 5.3 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 ORY50465.1 - 0.35 10.8 1.4 23 4.9 0.1 2.9 3 0 0 3 3 3 0 NACHT domain Bac_export_2 PF01312.19 ORY50465.1 - 4.4 6.4 15.3 0.028 13.6 4.2 2.6 3 0 0 3 3 3 0 FlhB HrpN YscU SpaS Family DivIC PF04977.15 ORY50467.1 - 0.12 12.2 0.1 5 7.0 0.2 2.2 2 0 0 2 2 2 0 Septum formation initiator Isochorismatase PF00857.20 ORY50469.1 - 3.3e-26 92.5 0.0 4e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Ku_N PF03731.15 ORY50469.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain Resolvase PF00239.21 ORY50470.1 - 2.5e-11 43.9 0.1 5.8e-11 42.7 0.1 1.7 1 1 0 1 1 1 1 Resolvase, N terminal domain THF_DHG_CYH PF00763.23 ORY50470.1 - 0.038 14.2 0.0 0.084 13.1 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Ank_2 PF12796.7 ORY50471.1 - 8e-40 135.3 0.0 3e-07 30.9 0.0 5.8 2 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY50471.1 - 5.7e-18 64.7 4.3 0.055 13.8 0.0 8.5 3 3 6 9 9 9 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY50471.1 - 5.6e-15 55.5 0.4 0.0067 17.0 0.0 6.8 5 1 0 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY50471.1 - 5.9e-15 53.9 5.2 0.94 10.2 0.1 10.3 11 0 0 11 11 11 3 Ankyrin repeat Ank PF00023.30 ORY50471.1 - 1e-07 32.0 2.8 13 6.4 0.0 7.1 7 1 1 8 8 8 2 Ankyrin repeat Tyrosinase PF00264.20 ORY50473.1 - 8.7e-18 65.4 13.8 8.1e-16 59.0 11.2 2.9 2 1 0 2 2 2 1 Common central domain of tyrosinase Anoctamin PF04547.12 ORY50474.1 - 5.5e-112 374.9 2.1 9.7e-112 374.1 2.1 1.4 1 1 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 ORY50474.1 - 1.1e-25 90.7 0.1 2.5e-25 89.5 0.1 1.6 1 1 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin RGCC PF15151.6 ORY50474.1 - 1.5 9.0 6.5 0.083 13.1 0.8 1.7 2 0 0 2 2 2 0 Response gene to complement 32 protein family Cyclin_C_2 PF16899.5 ORY50475.1 - 8.5e-12 45.4 2.9 1.7e-07 31.5 0.4 2.6 2 1 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 ORY50475.1 - 1.1e-08 34.9 0.2 2.2e-08 33.9 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain GCK PF07802.11 ORY50475.1 - 0.078 13.4 0.3 0.2 12.1 0.3 1.7 1 0 0 1 1 1 0 GCK domain DnaJ_C PF01556.18 ORY50476.1 - 3e-39 134.5 0.1 4.1e-39 134.0 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORY50476.1 - 1.2e-22 79.8 2.6 2.5e-22 78.8 2.6 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ORY50476.1 - 2.3e-09 37.5 22.7 4.5e-09 36.5 22.7 1.5 1 0 0 1 1 1 1 DnaJ central domain tRNA_Me_trans PF03054.16 ORY50477.1 - 5.5e-106 354.3 0.0 3e-68 230.2 0.0 2.0 2 0 0 2 2 2 2 tRNA methyl transferase NAD_synthase PF02540.17 ORY50477.1 - 1.6e-08 34.0 0.0 2.8e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 NAD synthase Asn_synthase PF00733.21 ORY50477.1 - 0.0015 18.3 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase ATP_bind_3 PF01171.20 ORY50477.1 - 0.032 14.0 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 PP-loop family AP_endonuc_2 PF01261.24 ORY50477.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel PAS PF00989.25 ORY50478.1 - 1.7e-07 31.2 0.0 7.5e-06 25.9 0.0 3.0 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 ORY50478.1 - 3.1e-06 27.4 0.1 5.1e-05 23.5 0.0 2.7 2 0 0 2 2 2 1 PAS domain Insulin_TMD PF17870.1 ORY50478.1 - 0.019 15.1 0.6 0.019 15.1 0.6 3.6 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment Orf78 PF06024.12 ORY50478.1 - 0.091 13.1 9.5 8.1 6.8 0.2 3.9 3 0 0 3 3 3 0 Orf78 (ac78) Aldose_epim PF01263.20 ORY50479.1 - 2e-59 201.3 0.0 2.6e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Ras PF00071.22 ORY50480.1 - 1.2e-53 181.0 0.0 1.5e-53 180.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY50480.1 - 9.4e-20 71.0 0.0 1.5e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY50480.1 - 1.9e-06 27.4 0.0 2.5e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY50480.1 - 0.0024 17.4 0.1 0.029 13.9 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY50480.1 - 0.0053 16.8 0.0 0.0099 16.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY50480.1 - 0.019 14.5 0.2 0.11 12.0 0.2 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B RsgA_GTPase PF03193.16 ORY50480.1 - 0.021 14.8 0.0 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase SRPRB PF09439.10 ORY50480.1 - 0.074 12.5 0.1 0.34 10.3 0.0 2.1 1 1 1 2 2 2 0 Signal recognition particle receptor beta subunit CbiA PF01656.23 ORY50480.1 - 0.081 13.0 0.2 0.33 11.0 0.0 1.9 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.6 ORY50480.1 - 0.11 12.9 0.1 0.2 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 ORY50480.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 ORY50481.1 - 2.7e-54 183.1 0.0 3.1e-54 182.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY50481.1 - 1.7e-20 73.4 0.0 2.5e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY50481.1 - 3e-09 36.6 0.0 3.8e-09 36.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 ORY50481.1 - 3.9e-06 26.5 0.1 8.4e-06 25.5 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 ORY50481.1 - 0.0055 16.8 0.0 0.015 15.4 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY50481.1 - 0.0073 15.9 0.2 0.15 11.6 0.2 2.6 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF5644 PF18712.1 ORY50481.1 - 0.069 13.2 0.0 1.7 8.7 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5644) PMT PF02366.18 ORY50482.1 - 1.5e-78 263.8 16.2 1.5e-78 263.8 16.2 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORY50482.1 - 4.5e-59 199.4 12.3 4.5e-59 199.4 12.3 2.0 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORY50482.1 - 3.1e-30 105.4 0.0 5.1e-30 104.7 0.0 1.3 1 0 0 1 1 1 1 MIR domain FtsL PF04999.13 ORY50483.1 - 0.082 12.9 2.3 0.15 12.1 0.2 2.6 2 0 0 2 2 2 0 Cell division protein FtsL Ras PF00071.22 ORY50484.1 - 4.9e-64 214.8 0.3 5.9e-64 214.6 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY50484.1 - 1.7e-35 121.8 0.1 2.7e-35 121.2 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY50484.1 - 2.3e-13 50.0 0.1 2.7e-13 49.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 ORY50484.1 - 1.3e-07 31.7 0.1 2.5e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY50484.1 - 5.7e-06 26.3 0.2 0.019 14.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 ORY50484.1 - 0.00019 21.0 0.1 0.001 18.6 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 ORY50484.1 - 0.00054 20.2 0.0 0.0043 17.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.12 ORY50484.1 - 0.0026 17.2 0.1 0.0039 16.6 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 ORY50484.1 - 0.0026 17.3 0.1 0.0066 16.0 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.6 ORY50484.1 - 0.0049 16.9 0.1 0.011 15.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 ORY50484.1 - 0.01 15.6 0.0 0.028 14.2 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 ORY50484.1 - 0.012 15.1 0.0 0.027 13.9 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 ORY50484.1 - 0.012 16.0 0.1 0.018 15.4 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 ORY50484.1 - 0.015 15.8 0.2 0.025 15.1 0.2 1.6 1 1 0 1 1 1 0 ABC transporter AEP1 PF17049.5 ORY50484.1 - 0.043 12.9 0.0 0.055 12.5 0.0 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 AAA_24 PF13479.6 ORY50484.1 - 0.05 13.3 0.1 0.084 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY50484.1 - 0.064 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 ORY50484.1 - 0.067 12.6 0.0 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_32 PF13654.6 ORY50484.1 - 0.072 11.9 0.0 0.2 10.4 0.0 1.6 1 1 1 2 2 2 0 AAA domain MCM PF00493.23 ORY50484.1 - 0.076 12.1 0.0 0.23 10.6 0.0 1.8 2 0 0 2 2 2 0 MCM P-loop domain AAA_28 PF13521.6 ORY50484.1 - 0.093 13.0 0.1 1.4 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 ORY50484.1 - 0.11 12.3 0.8 0.16 11.8 0.7 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FAD-SLDH PF12318.8 ORY50484.1 - 0.12 12.5 0.1 0.24 11.5 0.1 1.6 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase Dcc1 PF09724.9 ORY50485.1 - 7.9e-79 265.4 0.3 9e-79 265.2 0.3 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 RNase_H2-Ydr279 PF09468.10 ORY50485.1 - 0.057 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) wHTH domain Asp PF00026.23 ORY50486.1 - 4e-54 184.2 1.3 6.3e-54 183.5 1.3 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 ORY50486.1 - 2.9e-06 27.1 0.0 6.4e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 ORY50486.1 - 0.00066 20.0 0.3 0.00066 20.0 0.3 3.1 3 1 1 4 4 4 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 ORY50486.1 - 0.019 15.6 0.0 0.058 14.0 0.0 1.9 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 ORY50486.1 - 0.059 13.9 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Mcp5_PH PF12814.7 ORY50489.1 - 1.1e-14 54.6 0.3 3e-14 53.2 0.3 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TMCO5 PF14992.6 ORY50489.1 - 0.005 16.5 15.3 0.005 16.5 15.3 2.8 2 1 1 3 3 3 1 TMCO5 family EF1_GNE PF00736.19 ORY50489.1 - 0.032 14.4 0.3 17 5.7 0.1 3.0 2 0 0 2 2 2 0 EF-1 guanine nucleotide exchange domain FlaC_arch PF05377.11 ORY50489.1 - 1.4 9.3 19.1 19 5.7 0.1 5.5 4 1 0 5 5 5 0 Flagella accessory protein C (FlaC) LapA_dom PF06305.11 ORY50489.1 - 2.2 8.2 7.6 1.6 8.6 0.8 3.5 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain HALZ PF02183.18 ORY50489.1 - 3.2 8.1 21.9 5.4 7.3 1.1 5.5 4 1 1 5 5 5 0 Homeobox associated leucine zipper DUF5082 PF16888.5 ORY50489.1 - 3.8 7.8 25.8 0.23 11.7 3.5 4.0 3 2 0 3 3 3 0 Domain of unknown function (DUF5082) Cnn_1N PF07989.11 ORY50489.1 - 4.8 7.4 30.7 0.23 11.7 2.3 4.7 4 2 0 4 4 4 0 Centrosomin N-terminal motif 1 Methyltransf_11 PF08241.12 ORY50490.1 - 8.7e-11 42.3 0.0 1.4e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY50490.1 - 3e-09 37.5 0.0 5e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY50490.1 - 1.7e-05 25.5 0.0 4.6e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY50490.1 - 0.00013 21.9 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY50490.1 - 0.0013 18.5 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 ORY50490.1 - 0.036 13.3 0.0 0.058 12.7 0.0 1.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.19 ORY50490.1 - 0.041 13.6 0.0 0.085 12.6 0.0 1.6 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AdoMet_MTase PF07757.13 ORY50490.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 ORY50490.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 1 1 1 2 2 2 0 Methyltransferase domain TPMT PF05724.11 ORY50490.1 - 0.18 11.4 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) PIH1 PF08190.12 ORY50491.1 - 2.2e-12 46.8 1.5 4e-12 45.9 0.4 1.9 2 1 0 2 2 2 1 PIH1 N-terminal domain PIH1_CS PF18201.1 ORY50491.1 - 0.044 14.2 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 PIH1 CS-like domain FTCD_C PF04961.12 ORY50491.1 - 0.059 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Hexokinase_2 PF03727.16 ORY50492.1 - 6.1e-85 284.5 0.0 8e-85 284.1 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 ORY50492.1 - 1.4e-56 191.6 0.1 2.1e-56 191.0 0.1 1.3 1 0 0 1 1 1 1 Hexokinase Amidohydro_1 PF01979.20 ORY50493.1 - 1.8e-21 76.9 0.2 2.5e-21 76.4 0.2 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 ORY50493.1 - 3.6e-09 36.6 0.0 6.4e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family DUF1691 PF07950.11 ORY50493.1 - 0.16 12.7 0.0 0.44 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) Glucosamine_iso PF01182.20 ORY50494.1 - 9.6e-21 74.7 0.0 1.5e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Sec7 PF01369.20 ORY50495.1 - 1.4e-28 99.8 0.0 1.6e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Sec7 domain PNTB PF02233.16 ORY50496.1 - 2.8e-156 521.1 33.2 2.1e-128 429.1 4.8 3.4 2 1 1 3 3 3 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 ORY50496.1 - 4.9e-71 238.4 0.1 1e-70 237.4 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 ORY50496.1 - 5e-44 149.9 0.2 9.8e-44 149.0 0.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 ORY50496.1 - 1.6e-31 108.6 4.9 1.6e-31 108.6 4.9 3.4 3 1 0 3 3 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch Pyr_redox_2 PF07992.14 ORY50496.1 - 0.0044 16.3 0.3 0.0096 15.2 0.2 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 ORY50496.1 - 0.082 12.0 1.7 0.14 11.2 1.7 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.22 ORY50496.1 - 0.094 11.8 0.9 0.16 11.0 0.9 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 ORY50496.1 - 0.18 11.1 4.0 1.3 8.4 0.1 3.3 4 0 0 4 4 4 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 ORY50496.1 - 4.2 7.7 7.4 0.27 11.5 1.2 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain peroxidase PF00141.23 ORY50498.1 - 4.6e-21 75.6 0.0 5.3e-19 68.8 0.0 1.9 1 1 1 2 2 2 2 Peroxidase HD PF01966.22 ORY50498.1 - 0.015 15.6 0.0 1.2 9.4 0.0 2.2 2 0 0 2 2 2 0 HD domain S1-P1_nuclease PF02265.16 ORY50499.1 - 7.6e-49 166.8 0.5 1e-48 166.4 0.5 1.2 1 0 0 1 1 1 1 S1/P1 Nuclease TagF_N PF09867.9 ORY50499.1 - 0.02 14.9 0.1 0.04 13.9 0.1 1.5 1 0 0 1 1 1 0 TagF N-terminal domain, Type VI secretion system-associated Siva PF05458.12 ORY50501.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Cd27 binding protein (Siva) peroxidase PF00141.23 ORY50503.1 - 3.8e-20 72.6 0.0 1.1e-19 71.0 0.0 1.7 1 1 0 1 1 1 1 Peroxidase CDH-cyt PF16010.5 ORY50503.1 - 0.0056 16.4 1.1 0.015 14.9 0.2 2.1 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase DOMON PF03351.17 ORY50503.1 - 0.013 15.8 0.3 0.035 14.3 0.1 1.8 2 0 0 2 2 2 0 DOMON domain AATase PF07247.12 ORY50504.1 - 0.083 11.4 0.4 0.16 10.5 0.0 1.6 2 0 0 2 2 2 0 Alcohol acetyltransferase Helicase_C PF00271.31 ORY50505.1 - 3.9e-08 33.6 0.0 1.2e-07 32.0 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY50505.1 - 2e-06 27.7 0.0 3.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase PROCN PF08083.11 ORY50506.1 - 6.9e-236 782.5 8.1 1.2e-235 781.8 8.1 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 ORY50506.1 - 3.3e-130 432.6 0.7 5.7e-130 431.9 0.7 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 ORY50506.1 - 7.9e-90 298.9 2.4 2.3e-89 297.4 2.4 1.9 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 ORY50506.1 - 8e-87 288.9 4.0 2.1e-86 287.5 4.0 1.8 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 ORY50506.1 - 3.9e-74 247.1 0.1 7.7e-74 246.1 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 ORY50506.1 - 4.9e-51 171.8 0.0 1.5e-50 170.2 0.0 1.9 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 ORY50506.1 - 1.1e-46 157.0 1.0 3.3e-46 155.6 1.0 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 ORY50506.1 - 6.1e-09 35.9 0.0 1.5e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Cript PF10235.9 ORY50507.1 - 1.1e-23 83.6 8.5 1.1e-23 83.6 8.5 1.7 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DUF2039 PF10217.9 ORY50507.1 - 0.001 19.4 5.2 0.001 19.4 5.2 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) SR-25 PF10500.9 ORY50507.1 - 0.027 14.1 5.6 0.027 14.1 5.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cytochrom_c3_2 PF14537.6 ORY50507.1 - 0.9 10.0 9.9 0.33 11.4 6.6 2.0 2 1 0 2 2 2 0 Cytochrome c3 zf-dskA_traR PF01258.17 ORY50507.1 - 1.2 9.1 0.0 1.2 9.1 0.0 3.3 4 0 0 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger zinc_ribbon_2 PF13240.6 ORY50507.1 - 1.3 8.9 13.4 17 5.3 6.8 3.7 3 1 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 ORY50507.1 - 1.4 9.7 13.6 3.8 8.3 10.3 2.7 2 1 0 2 2 2 0 zinc-ribbon family DNA_RNApol_7kD PF03604.13 ORY50507.1 - 5.1 6.9 13.6 24 4.7 0.1 4.1 3 1 1 4 4 4 0 DNA directed RNA polymerase, 7 kDa subunit AAA_16 PF13191.6 ORY50509.1 - 0.017 15.5 0.0 0.26 11.6 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain Suv3_C_1 PF18147.1 ORY50510.1 - 1.6e-12 47.1 0.2 3.2e-12 46.1 0.2 1.6 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 ORY50510.1 - 2.2e-10 40.9 0.0 4.2e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SUV3_C PF12513.8 ORY50510.1 - 0.0022 17.9 1.5 0.0082 16.1 1.6 1.9 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal AAA_22 PF13401.6 ORY50510.1 - 0.037 14.3 0.1 0.25 11.6 0.0 2.2 2 1 0 2 2 2 0 AAA domain ABC_membrane PF00664.23 ORY50511.1 - 3.9e-59 200.5 34.6 4.6e-32 111.8 7.7 3.2 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY50511.1 - 7.1e-53 178.8 0.1 1.2e-29 103.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY50511.1 - 7.5e-14 51.7 2.7 0.00013 21.5 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY50511.1 - 9.9e-07 28.8 0.4 0.015 15.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 ORY50511.1 - 1.7e-06 27.7 1.2 0.011 15.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY50511.1 - 2.5e-05 24.2 1.6 0.031 14.2 1.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 ORY50511.1 - 4.2e-05 24.2 0.9 0.15 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 ORY50511.1 - 0.00016 21.6 6.9 0.019 14.8 0.0 3.4 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 ORY50511.1 - 0.00052 20.1 0.8 0.59 10.2 0.1 3.0 3 0 0 3 3 3 2 Dynamin family AAA_16 PF13191.6 ORY50511.1 - 0.001 19.4 0.4 0.16 12.3 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain DUF87 PF01935.17 ORY50511.1 - 0.0018 18.4 3.0 0.052 13.6 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain DUF815 PF05673.13 ORY50511.1 - 0.0035 16.5 0.7 0.21 10.7 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 ORY50511.1 - 0.0093 15.5 1.7 0.72 9.3 0.0 2.7 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_22 PF13401.6 ORY50511.1 - 0.02 15.2 1.3 0.37 11.1 0.1 2.7 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 ORY50511.1 - 0.031 13.6 0.7 1.1 8.5 0.0 2.6 3 0 0 3 3 3 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 ORY50511.1 - 0.035 13.4 0.9 6.5 6.0 0.3 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.6 ORY50511.1 - 0.04 13.6 8.6 1.1 8.9 0.1 3.5 3 1 1 4 4 4 0 AAA ATPase domain cobW PF02492.19 ORY50511.1 - 0.04 13.5 0.8 2.6 7.6 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.9 ORY50511.1 - 0.042 12.8 5.2 0.7 8.7 0.1 2.9 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 ORY50511.1 - 0.047 13.4 2.1 2.8 7.6 0.1 2.8 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 ORY50511.1 - 0.048 12.6 1.2 2.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 ORY50511.1 - 0.078 12.7 0.6 4.4 7.0 0.0 3.3 4 0 0 4 4 4 0 IstB-like ATP binding protein RNA_helicase PF00910.22 ORY50511.1 - 0.11 12.9 0.4 3.6 8.0 0.0 3.1 3 0 0 3 3 3 0 RNA helicase NB-ARC PF00931.22 ORY50511.1 - 0.12 11.5 1.9 1.3 8.2 0.0 2.9 2 1 0 2 2 2 0 NB-ARC domain ABC_ATPase PF09818.9 ORY50511.1 - 0.15 10.9 0.3 1.1 8.0 0.1 2.4 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_5 PF07728.14 ORY50511.1 - 0.18 11.8 1.4 7.7 6.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 ORY50511.1 - 0.2 11.6 2.3 2.5 8.0 0.1 2.6 2 0 0 2 2 2 0 NACHT domain Roc PF08477.13 ORY50511.1 - 1.1 9.5 5.1 2.7 8.2 0.1 3.2 4 0 0 4 4 2 0 Ras of Complex, Roc, domain of DAPkinase PC-Esterase PF13839.6 ORY50512.1 - 0.042 13.6 0.0 0.044 13.5 0.0 1.1 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p OPT PF03169.15 ORY50514.1 - 8.5e-53 179.9 23.1 1.4e-31 109.9 6.7 2.8 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Sulf_transp PF04143.14 ORY50517.1 - 3.5e-34 118.8 19.7 6.1e-34 118.0 19.7 1.4 1 0 0 1 1 1 1 Sulphur transport Kelch_5 PF13854.6 ORY50519.1 - 1.8e-14 53.3 2.0 1.8e-05 24.6 0.3 5.1 5 0 0 5 5 5 3 Kelch motif zf-MYND PF01753.18 ORY50519.1 - 4.6e-10 39.4 11.1 9.7e-10 38.4 11.1 1.5 1 0 0 1 1 1 1 MYND finger Kelch_4 PF13418.6 ORY50519.1 - 4.4e-08 33.0 1.0 0.012 15.6 0.1 3.8 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_2 PF07646.15 ORY50519.1 - 2.1e-06 27.5 6.6 1.5 8.9 0.4 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 ORY50519.1 - 5.1e-06 26.6 1.0 1.3 9.4 0.0 4.1 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY50519.1 - 4.6e-05 23.5 7.8 0.033 14.5 0.1 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 ORY50519.1 - 0.0037 16.8 10.3 0.26 10.9 0.4 4.8 5 0 0 5 5 5 2 Kelch motif Sugar_tr PF00083.24 ORY50521.1 - 4.1e-42 144.6 19.3 1.8e-41 142.5 19.3 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY50521.1 - 7.1e-23 81.1 32.4 1.1e-17 64.1 9.7 2.4 1 1 1 3 3 3 2 Major Facilitator Superfamily MFS_4 PF06779.14 ORY50521.1 - 0.00017 21.0 7.7 0.0004 19.8 7.7 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Cro PF09048.10 ORY50521.1 - 0.16 12.1 0.0 0.3 11.2 0.0 1.4 1 0 0 1 1 1 0 Cro fn3_2 PF16893.5 ORY50522.1 - 1.2e-26 92.7 0.1 1.8e-26 92.1 0.1 1.3 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 ORY50522.1 - 1.8e-23 82.2 0.1 3.2e-23 81.4 0.1 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 ORY50522.1 - 6.3e-17 61.3 0.0 1.2e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 ORY50522.1 - 2e-09 37.7 0.0 6.9e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 ORY50522.1 - 2.9e-06 27.4 0.0 5.5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.21 ORY50522.1 - 0.00038 20.7 0.1 0.0015 18.9 0.1 1.9 1 1 0 1 1 1 1 Fibronectin type III domain PolyG_pol PF01518.16 ORY50522.1 - 0.073 11.8 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Sigma NS protein BRCT_2 PF16589.5 ORY50522.1 - 0.11 12.9 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain CsbD PF05532.12 ORY50523.1 - 0.0021 17.9 5.6 0.0021 17.9 5.6 2.1 2 0 0 2 2 2 1 CsbD-like LXG PF04740.12 ORY50523.1 - 0.003 17.3 0.8 0.0041 16.9 0.8 1.1 1 0 0 1 1 1 1 LXG domain of WXG superfamily DUF883 PF05957.13 ORY50523.1 - 0.0031 18.1 0.1 0.0041 17.7 0.1 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF883) LuxS PF02664.15 ORY50523.1 - 0.042 13.5 0.2 0.058 13.1 0.2 1.1 1 0 0 1 1 1 0 S-Ribosylhomocysteinase (LuxS) YlqD PF11068.8 ORY50523.1 - 0.045 14.1 11.6 0.059 13.7 11.6 1.1 1 0 0 1 1 1 0 YlqD protein DUF4407 PF14362.6 ORY50523.1 - 0.084 12.2 6.6 0.1 11.9 6.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) REF PF05755.12 ORY50523.1 - 0.16 11.8 1.3 0.2 11.4 1.3 1.1 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) ABC2_membrane_3 PF12698.7 ORY50523.1 - 0.25 10.4 1.7 0.3 10.2 1.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein TFIIA PF03153.13 ORY50523.1 - 0.66 9.9 10.6 0.69 9.9 10.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ATP-synt_B PF00430.18 ORY50523.1 - 1.7 8.8 12.0 2.4 8.3 12.0 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Mobilization_B PF17511.2 ORY50523.1 - 1.7 9.0 8.9 2.4 8.5 8.9 1.2 1 0 0 1 1 1 0 Mobilization protein B V-SNARE PF05008.15 ORY50523.1 - 3.6 8.0 8.0 23 5.4 8.0 1.9 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus DUF1525 PF07511.11 ORY50523.1 - 4.1 7.6 11.5 17 5.6 11.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1525) S1-P1_nuclease PF02265.16 ORY50525.1 - 3.4e-24 86.0 0.1 5.5e-24 85.3 0.1 1.3 1 0 0 1 1 1 1 S1/P1 Nuclease Mucin PF01456.17 ORY50525.1 - 0.23 11.4 28.0 0.56 10.2 28.0 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Peptidase_C97 PF05903.14 ORY50529.1 - 1.4e-37 128.9 0.0 2e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.11 ORY50529.1 - 3.1e-35 121.7 1.5 4.3e-35 121.3 1.5 1.2 1 0 0 1 1 1 1 PUL domain DUF3730 PF12530.8 ORY50529.1 - 0.027 14.0 0.6 0.053 13.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) Leu_Phe_trans PF03588.14 ORY50531.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase GST_C_2 PF13410.6 ORY50532.1 - 1.1e-08 34.9 0.0 3.1e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY50532.1 - 2.5e-06 27.6 0.1 1.1e-05 25.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 ORY50532.1 - 3.1e-05 24.3 0.0 0.00012 22.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 ORY50532.1 - 3.1e-05 24.5 0.0 6.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY50532.1 - 3.5e-05 24.0 0.0 0.00016 21.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 ORY50532.1 - 0.00068 20.3 0.1 0.065 14.0 0.0 2.4 1 1 1 2 2 2 1 Glutathione S-transferase N-terminal domain Glutaredoxin2_C PF04399.13 ORY50532.1 - 0.00082 19.2 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain GST_C_3 PF14497.6 ORY50532.1 - 0.0015 18.7 0.0 0.0033 17.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY50532.1 - 0.0047 17.3 0.0 0.013 15.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 ORY50532.1 - 0.13 12.6 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein PilJ PF13675.6 ORY50532.1 - 0.18 11.8 0.0 4.8 7.2 0.0 2.7 3 1 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Ni_hydr_CYTB PF01292.20 ORY50533.1 - 4.1e-19 68.9 6.7 4.8e-19 68.6 6.7 1.0 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 CK2S PF15011.6 ORY50536.1 - 0.0052 16.7 0.6 0.0052 16.7 0.6 2.3 1 1 1 2 2 2 1 Casein Kinase 2 substrate GCN5L1 PF06320.13 ORY50536.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.6 3 0 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) PspB PF06667.12 ORY50536.1 - 0.14 12.2 0.6 0.41 10.7 0.0 2.1 2 0 0 2 2 2 0 Phage shock protein B AnfO_nitrog PF09582.10 ORY50536.1 - 0.28 10.5 3.5 0.58 9.5 0.8 2.4 1 1 1 2 2 2 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) DUF3682 PF12446.8 ORY50537.1 - 0.023 15.2 1.9 0.023 15.2 1.9 4.9 5 1 1 6 6 6 0 Protein of unknown function (DUF3682) DUF1003 PF06210.11 ORY50541.1 - 0.0067 16.5 1.4 0.011 15.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1003) MHYT PF03707.16 ORY50541.1 - 6.1 7.1 7.2 0.57 10.4 0.8 2.6 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat DUF4293 PF14126.6 ORY50542.1 - 0.027 14.7 1.4 0.027 14.7 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Bcl-2 PF00452.19 ORY50542.1 - 0.14 12.9 0.0 0.36 11.6 0.0 1.6 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family DUF420 PF04238.12 ORY50543.1 - 0.16 12.3 0.2 0.16 12.3 0.2 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF420) EST1_DNA_bind PF10373.9 ORY50544.1 - 5e-19 68.8 0.0 3.3e-18 66.2 0.0 2.3 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain PIN_4 PF13638.6 ORY50544.1 - 0.00023 21.5 0.0 0.00048 20.4 0.0 1.5 1 0 0 1 1 1 1 PIN domain PI3K_p85B PF02192.16 ORY50544.1 - 0.083 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 PI3-kinase family, p85-binding domain DLIC PF05783.11 ORY50544.1 - 3.2 6.5 4.4 5.3 5.8 4.4 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) CCDC106 PF15794.5 ORY50544.1 - 3.6 7.2 5.0 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 EST1 PF10374.9 ORY50544.1 - 6.3 7.5 8.2 7 7.3 0.5 3.4 2 2 0 2 2 2 0 Telomerase activating protein Est1 iPGM_N PF06415.13 ORY50545.1 - 7.2e-66 221.7 0.0 5.1e-65 218.9 0.0 2.0 1 1 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 ORY50545.1 - 1e-53 182.2 0.0 5.7e-50 170.0 0.0 3.0 1 1 0 1 1 1 1 Metalloenzyme superfamily Carb_kinase PF01256.17 ORY50545.1 - 0.00066 19.2 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate kinase DUF5598 PF18127.1 ORY50545.1 - 0.025 15.0 0.0 0.13 12.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5598) Flp_N PF03930.14 ORY50545.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Recombinase Flp protein N-terminus LRR_8 PF13855.6 ORY50546.1 - 0.052 13.3 1.2 0.52 10.1 0.1 2.6 2 0 0 2 2 2 0 Leucine rich repeat Pentapeptide_2 PF01469.18 ORY50547.1 - 0.0012 18.7 14.0 0.0012 18.7 14.0 1.9 2 0 0 2 2 2 1 Pentapeptide repeats (8 copies) Enolase_C PF00113.22 ORY50548.1 - 5.5e-155 515.0 0.4 1.4e-154 513.7 0.1 1.7 2 0 0 2 2 2 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 ORY50548.1 - 8.4e-60 200.7 0.1 1.7e-59 199.7 0.1 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 ORY50548.1 - 9.6e-10 38.4 0.0 1.9e-09 37.4 0.0 1.6 1 1 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 ORY50548.1 - 0.0024 17.1 0.3 0.0054 15.9 0.1 1.7 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus IMS PF00817.20 ORY50548.1 - 0.13 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 impB/mucB/samB family Stress-antifung PF01657.17 ORY50549.1 - 0.018 15.7 0.7 0.021 15.5 0.7 1.1 1 0 0 1 1 1 0 Salt stress response/antifungal Erf4 PF10256.9 ORY50550.1 - 0.098 12.8 0.1 0.24 11.5 0.1 1.7 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family S6OS1 PF15676.5 ORY50551.1 - 0.38 9.2 0.0 0.38 9.2 0.0 2.1 2 0 0 2 2 2 0 Six6 opposite strand transcript 1 family LRR_4 PF12799.7 ORY50552.1 - 0.25 11.8 6.5 9.2 6.8 0.6 3.0 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) RSN1_7TM PF02714.15 ORY50554.1 - 2.2e-30 105.9 23.3 8.3e-20 71.2 3.3 3.6 3 1 1 4 4 4 3 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 ORY50554.1 - 3.2e-19 69.8 0.1 5.1e-19 69.2 0.1 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 ORY50554.1 - 1.4e-12 47.6 2.8 1.4e-12 47.6 2.8 3.3 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 ORY50554.1 - 0.0017 18.5 0.0 0.0035 17.5 0.0 1.5 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Pam17 PF08566.10 ORY50554.1 - 0.1 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 NPCC PF08058.11 ORY50554.1 - 8.7 6.4 6.4 3.8 7.6 0.3 2.7 3 0 0 3 3 3 0 Nuclear pore complex component TPR_1 PF00515.28 ORY50555.1 - 1.6e-20 72.0 7.4 0.00026 20.6 0.1 7.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 ORY50555.1 - 1.2e-16 60.9 8.7 0.00056 20.4 0.4 6.3 5 2 2 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY50555.1 - 5.7e-16 57.3 2.3 0.0004 20.4 0.0 8.3 8 1 1 9 9 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY50555.1 - 1.8e-15 56.1 4.1 3.4e-05 23.9 0.0 7.3 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORY50555.1 - 3.2e-15 55.5 7.1 0.00046 20.8 0.5 7.0 6 1 1 7 7 5 5 Tetratricopeptide repeat TPR_2 PF07719.17 ORY50555.1 - 7.9e-15 53.7 15.8 0.0084 16.1 0.0 8.5 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_16 PF13432.6 ORY50555.1 - 2e-11 44.3 7.0 0.014 16.0 0.1 5.6 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY50555.1 - 2.5e-11 42.8 4.4 0.0025 17.7 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORY50555.1 - 3.5e-10 40.0 11.0 0.0018 18.5 0.1 5.7 4 2 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORY50555.1 - 1.6e-09 37.3 10.9 0.0034 17.0 0.1 6.6 6 1 1 7 7 7 3 TPR repeat TPR_6 PF13174.6 ORY50555.1 - 7.8e-09 35.6 6.5 0.012 16.2 0.0 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY50555.1 - 2.8e-06 27.4 1.9 0.15 12.2 0.0 5.1 4 1 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 ORY50555.1 - 4.7e-05 22.7 2.4 0.11 11.7 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 ORY50555.1 - 0.00016 22.0 0.4 2.1 8.7 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY50555.1 - 0.00025 21.2 12.5 0.51 10.6 0.2 5.0 5 1 0 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 ORY50555.1 - 0.0048 15.9 0.6 2.6 6.8 0.1 2.6 2 1 0 2 2 2 2 NMDA receptor-regulated protein 1 ChAPs PF09295.10 ORY50555.1 - 0.0098 14.9 0.1 0.22 10.5 0.0 2.1 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) Alkyl_sulf_dimr PF14863.6 ORY50555.1 - 0.015 15.7 0.5 24 5.4 0.0 3.7 3 1 0 3 3 3 0 Alkyl sulfatase dimerisation HrpB1_HrpK PF09613.10 ORY50555.1 - 0.034 13.8 0.8 0.44 10.2 0.2 2.7 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) PPR PF01535.20 ORY50555.1 - 0.05 13.9 1.1 62 4.2 0.0 4.4 5 0 0 5 5 3 0 PPR repeat TPR_4 PF07721.14 ORY50555.1 - 0.49 11.2 10.4 38 5.3 0.2 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY50555.1 - 2.6 8.0 11.4 3.1 7.8 0.2 4.6 6 0 0 6 6 4 0 Tetratricopeptide repeat Ysc84 PF04366.12 ORY50556.1 - 2.9e-41 140.2 1.2 5.4e-41 139.3 1.2 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Utp14 PF04615.13 ORY50557.1 - 2.4 6.6 17.5 4.3 5.8 17.5 1.3 1 0 0 1 1 1 0 Utp14 protein DUF155 PF02582.14 ORY50559.1 - 2e-39 135.5 0.0 3.5e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 FtsL PF04999.13 ORY50559.1 - 0.38 10.8 3.6 0.91 9.6 3.6 1.7 1 0 0 1 1 1 0 Cell division protein FtsL DUF4968 PF16338.5 ORY50560.1 - 0.019 15.3 0.0 0.038 14.3 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4968) DUF4939 PF16297.5 ORY50560.1 - 0.15 11.9 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4939) Glyco_hydro_31 PF01055.26 ORY50561.1 - 4.4e-72 243.6 5.8 8e-70 236.2 5.8 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 DUF5110 PF17137.4 ORY50561.1 - 2.1e-09 37.5 0.0 4.3e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) RE_LlaMI PF09562.10 ORY50561.1 - 1.9 8.0 6.1 0.2 11.2 0.4 2.2 3 0 0 3 3 3 0 LlaMI restriction endonuclease DUF155 PF02582.14 ORY50562.1 - 7e-42 143.5 0.0 1.4e-41 142.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 FAM86 PF14904.6 ORY50563.1 - 0.028 14.5 0.0 0.059 13.5 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function E1-E2_ATPase PF00122.20 ORY50565.1 - 5.3e-49 166.2 0.3 5.3e-49 166.2 0.3 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 ORY50565.1 - 5.5e-21 75.1 13.8 3.8e-16 59.3 5.2 3.0 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 ORY50565.1 - 4.7e-18 66.2 0.8 8.3e-10 39.3 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY50565.1 - 1.9e-17 63.1 0.0 3.9e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 ORY50565.1 - 0.0023 17.7 1.1 0.17 11.6 0.6 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FIST PF08495.10 ORY50565.1 - 0.15 12.0 0.2 0.49 10.4 0.2 1.8 1 0 0 1 1 1 0 FIST N domain Strabismus PF06638.11 ORY50565.1 - 0.6 8.7 2.4 0.97 8.0 2.4 1.2 1 0 0 1 1 1 0 Strabismus protein FAM220 PF15487.6 ORY50568.1 - 7.8 6.0 10.7 4.6 6.8 8.2 1.7 1 1 1 2 2 2 0 FAM220 family DUF3754 PF12576.8 ORY50569.1 - 0.038 13.9 1.1 0.19 11.6 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) zf-C3HC4_2 PF13923.6 ORY50570.1 - 9.5e-12 44.6 5.9 9.5e-12 44.6 5.9 4.6 3 2 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY50570.1 - 4.8e-10 39.1 3.8 4.8e-10 39.1 3.8 4.6 2 1 2 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY50570.1 - 2.9e-09 36.8 6.3 2.9e-09 36.8 6.3 4.2 3 1 1 4 4 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 ORY50570.1 - 7.8e-09 35.7 5.5 7.8e-09 35.7 5.5 3.9 2 1 0 3 3 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORY50570.1 - 2.5e-07 30.5 2.7 2.5e-07 30.5 2.7 4.1 3 2 1 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY50570.1 - 8.7e-07 29.0 4.8 8.7e-07 29.0 4.8 3.8 3 2 1 4 4 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 ORY50570.1 - 1e-06 28.6 2.3 1e-06 28.6 2.3 4.3 2 1 0 2 2 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 ORY50570.1 - 2.4e-05 24.4 2.7 2.4e-05 24.4 2.7 3.4 3 0 0 3 3 3 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 ORY50570.1 - 3.7e-05 23.5 3.4 3.7e-05 23.5 3.4 3.5 3 1 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 ORY50570.1 - 0.0001 22.1 2.0 0.0001 22.1 2.0 2.8 3 0 0 3 3 2 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 ORY50570.1 - 0.00014 22.0 4.0 0.00014 22.0 4.0 3.3 2 2 0 2 2 1 1 RING-H2 zinc finger domain U-box PF04564.15 ORY50570.1 - 0.00016 21.8 0.1 0.00038 20.6 0.1 1.6 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 ORY50570.1 - 0.00022 21.0 2.2 0.00022 21.0 2.2 2.1 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 ORY50570.1 - 0.027 14.2 3.9 0.027 14.2 3.9 3.6 4 0 0 4 4 4 0 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORY50573.1 - 3.9e-10 39.4 0.9 3.9e-10 39.4 0.9 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY50573.1 - 3.8e-08 33.5 4.2 7e-07 29.4 2.1 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 ORY50573.1 - 8.2e-08 32.5 2.0 8.2e-08 32.5 2.0 3.7 3 1 1 4 4 3 1 Ring finger domain zf-C3HC4 PF00097.25 ORY50573.1 - 1.8e-06 27.7 0.7 1.8e-06 27.7 0.7 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY50573.1 - 7.9e-06 25.8 1.3 7.9e-06 25.8 1.3 3.2 3 0 0 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.6 ORY50573.1 - 0.00018 21.3 2.2 0.00018 21.3 2.2 3.3 3 2 0 3 3 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 ORY50573.1 - 0.00023 20.9 0.2 0.00023 20.9 0.2 2.2 3 0 0 3 3 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 ORY50573.1 - 0.00032 20.6 0.8 0.00032 20.6 0.8 3.4 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY50573.1 - 0.00037 20.3 0.7 0.00037 20.3 0.7 3.7 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 ORY50573.1 - 0.00061 19.6 0.2 0.0015 18.3 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 ORY50573.1 - 0.00064 19.8 0.6 0.00064 19.8 0.6 3.0 3 1 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 ORY50573.1 - 0.0027 17.7 0.5 0.0027 17.7 0.5 2.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 ORY50573.1 - 0.016 14.9 0.4 0.016 14.9 0.4 2.2 2 1 0 2 2 2 0 P-11 zinc finger zf-RING_10 PF16685.5 ORY50573.1 - 0.026 14.7 0.7 0.026 14.7 0.7 3.0 2 1 0 3 3 3 0 zinc RING finger of MSL2 DUF1244 PF06844.11 ORY50573.1 - 0.15 12.3 0.4 0.41 10.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) zf-C3HC4_2 PF13923.6 ORY50574.1 - 7.3e-12 44.9 6.3 7.3e-12 44.9 6.3 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY50574.1 - 2.6e-08 34.1 6.3 2.6e-08 34.1 6.3 2.9 2 1 1 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 ORY50574.1 - 5.1e-08 32.6 5.3 5.1e-08 32.6 5.3 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY50574.1 - 2.7e-07 30.8 3.5 7.9e-07 29.3 3.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ORY50574.1 - 4.6e-07 29.7 12.8 3.5e-06 26.9 6.8 2.6 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORY50574.1 - 2.6e-06 27.2 3.2 2.6e-06 27.2 3.2 3.0 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 ORY50574.1 - 8.1e-06 25.9 3.7 8.1e-06 25.9 3.7 2.1 2 1 0 2 2 2 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 ORY50574.1 - 3e-05 23.8 1.4 6.7e-05 22.7 1.4 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 ORY50574.1 - 6.4e-05 23.0 4.8 6.4e-05 23.0 4.8 2.7 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 ORY50574.1 - 0.00033 20.6 4.9 0.00033 20.6 4.9 2.6 2 1 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY50574.1 - 0.00051 19.8 3.4 0.00051 19.8 3.4 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 ORY50574.1 - 0.0012 18.6 1.8 0.0012 18.6 1.8 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 ORY50574.1 - 0.0051 16.8 1.5 0.0051 16.8 1.5 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Cadherin_C_2 PF16492.5 ORY50575.1 - 0.011 16.4 0.9 1.4 9.7 0.2 2.3 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal Cortexin PF11057.8 ORY50575.1 - 0.024 14.5 0.4 3 7.8 0.1 2.4 2 0 0 2 2 2 0 Cortexin of kidney Erv26 PF04148.13 ORY50575.1 - 0.036 13.9 0.5 0.055 13.3 0.5 1.3 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 FUN14 PF04930.15 ORY50575.1 - 0.12 12.8 4.7 0.18 12.3 1.5 2.3 2 1 0 2 2 2 0 FUN14 family DuoxA PF10204.9 ORY50575.1 - 0.13 11.3 4.3 0.058 12.4 0.6 1.9 2 0 0 2 2 2 0 Dual oxidase maturation factor MotA_ExbB PF01618.16 ORY50577.1 - 0.095 12.5 5.6 0.16 11.7 5.6 1.4 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family SH3_9 PF14604.6 ORY50579.1 - 5.5e-12 45.4 0.1 1e-11 44.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY50579.1 - 6.1e-11 41.8 0.1 1.4e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY50579.1 - 2.8e-09 36.4 3.1 1.2e-08 34.4 3.1 2.0 1 1 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 ORY50579.1 - 0.0014 18.9 0.3 0.0071 16.6 0.5 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain SidE PF12252.8 ORY50579.1 - 0.006 14.2 1.8 0.0073 13.9 1.8 1.0 1 0 0 1 1 1 1 Dot/Icm substrate protein DUF2730 PF10805.8 ORY50579.1 - 0.12 12.5 4.0 0.21 11.7 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF2894 PF11445.8 ORY50579.1 - 0.25 11.8 3.8 0.93 9.9 3.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) DUF1690 PF07956.11 ORY50579.1 - 3.9 7.9 7.4 1.6 9.2 2.6 2.2 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) FAM184 PF15665.5 ORY50579.1 - 3.9 7.2 7.4 4.6 7.0 1.4 2.3 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B DUF2207 PF09972.9 ORY50580.1 - 0.015 14.1 0.2 0.019 13.8 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TRC8_N PF13705.6 ORY50580.1 - 0.034 13.1 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 TRC8 N-terminal domain Abhydrolase_9_N PF15420.6 ORY50580.1 - 0.088 12.8 0.5 0.14 12.2 0.5 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus DUF2431 PF10354.9 ORY50581.1 - 4.5e-17 62.8 0.0 1.6e-16 61.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) Helicase_C PF00271.31 ORY50581.1 - 1.6e-09 38.1 0.0 3.4e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY50581.1 - 4.3e-07 29.9 0.0 1.2e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-CCCH_2 PF14608.6 ORY50581.1 - 0.00019 21.8 2.7 0.00019 21.8 2.7 2.4 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger AAA_19 PF13245.6 ORY50581.1 - 0.00031 21.1 0.0 0.0029 18.0 0.0 2.5 3 0 0 3 3 3 1 AAA domain zf-CCCH_4 PF18044.1 ORY50581.1 - 0.007 16.1 8.0 0.035 13.9 8.0 2.2 1 1 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 ORY50581.1 - 0.019 15.0 5.7 0.02 15.0 3.5 2.2 1 1 1 2 2 2 0 Zinc finger domain Pox_VLTF3 PF04947.14 ORY50585.1 - 0.034 13.9 0.1 0.056 13.2 0.1 1.3 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like HSBP1 PF06825.12 ORY50585.1 - 0.064 13.1 1.7 2 8.4 0.1 3.4 3 0 0 3 3 3 0 Heat shock factor binding protein 1 DUF677 PF05055.12 ORY50585.1 - 0.078 11.9 0.5 0.31 9.9 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF677) Syntaxin-6_N PF09177.11 ORY50585.1 - 0.18 12.4 3.4 6 7.5 0.1 3.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DASH_Dad3 PF08656.10 ORY50585.1 - 0.24 11.5 8.1 26 5.0 0.5 4.1 3 1 1 4 4 4 0 DASH complex subunit Dad3 Cauli_AT PF03233.13 ORY50585.1 - 0.3 11.0 2.1 16 5.4 0.1 3.2 3 1 0 3 3 3 0 Aphid transmission protein DUF1690 PF07956.11 ORY50585.1 - 0.41 11.1 2.6 1.7 9.1 0.6 2.3 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Prominin PF05478.11 ORY50585.1 - 0.87 7.5 2.7 0.36 8.7 0.3 1.4 2 0 0 2 2 2 0 Prominin MRP-S27 PF10037.9 ORY50585.1 - 1.3 7.8 3.4 1.5 7.6 1.0 1.9 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 COG5 PF10392.9 ORY50585.1 - 2 8.6 12.8 0.87 9.8 1.2 3.1 2 1 1 3 3 3 0 Golgi transport complex subunit 5 LRR_4 PF12799.7 ORY50586.1 - 3.2e-14 52.8 40.0 0.00098 19.5 5.4 4.6 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY50586.1 - 1.3e-09 37.3 11.9 4.6 7.5 0.5 6.7 6 0 0 6 6 6 6 Leucine Rich repeat LRR_1 PF00560.33 ORY50586.1 - 7.6e-08 31.9 15.7 3.8 8.4 0.2 6.8 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_8 PF13855.6 ORY50586.1 - 0.00097 18.9 22.4 0.65 9.8 2.1 4.9 2 2 2 4 4 4 2 Leucine rich repeat FNIP PF05725.12 ORY50586.1 - 0.016 15.4 19.7 29 4.9 13.9 4.5 1 1 2 3 3 3 0 FNIP Repeat LRR_2 PF07723.13 ORY50586.1 - 0.027 15.1 0.0 2.5 8.9 0.1 3.1 2 0 0 2 2 2 0 Leucine Rich Repeat Erf4 PF10256.9 ORY50587.1 - 0.027 14.6 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family DUF1304 PF06993.12 ORY50587.1 - 0.17 11.9 2.3 0.37 10.8 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) Yip1 PF04893.17 ORY50587.1 - 0.32 10.7 6.8 0.32 10.7 4.5 2.0 2 1 0 2 2 2 0 Yip1 domain VirB3 PF05101.13 ORY50587.1 - 0.43 10.8 3.2 0.77 10.0 3.2 1.4 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Zn_clus PF00172.18 ORY50588.1 - 0.079 13.1 6.8 0.12 12.5 6.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1980 PF09323.10 ORY50590.1 - 0.36 10.7 2.5 0.97 9.3 2.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF423 PF04241.15 ORY50591.1 - 3 8.1 8.2 0.55 10.5 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF423) DUF2434 PF10361.9 ORY50592.1 - 0.0043 16.1 11.4 0.059 12.3 11.4 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2434) DUF4231 PF14015.6 ORY50592.1 - 0.027 14.9 0.4 1.6 9.2 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2517 PF10725.9 ORY50594.1 - 0.049 13.4 1.8 0.33 10.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2517) WD40_4 PF16300.5 ORY50596.1 - 6.5e-12 45.1 0.0 1.5e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 ORY50596.1 - 0.53 11.2 4.5 1.6 9.7 0.9 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat TPR_12 PF13424.6 ORY50598.1 - 6.4e-66 218.6 0.5 1.6e-16 60.3 0.0 4.6 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 ORY50598.1 - 3.6e-64 211.1 0.0 1e-14 53.9 0.0 5.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 ORY50598.1 - 1.5e-16 59.1 0.1 2.2e-05 24.2 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORY50598.1 - 3.9e-15 54.9 3.9 2.9e-05 23.7 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY50598.1 - 1.9e-10 40.1 7.0 0.00021 21.2 0.2 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY50598.1 - 0.0003 20.7 3.9 0.13 12.4 0.0 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY50598.1 - 0.00034 20.8 2.6 0.13 12.7 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY50598.1 - 0.0027 18.4 0.0 19 6.4 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY50598.1 - 0.0096 15.3 0.0 0.31 10.4 0.0 2.1 1 1 0 2 2 2 1 MalT-like TPR region ANATO PF01821.18 ORY50598.1 - 0.017 16.0 0.2 2.1e+02 2.9 0.0 4.9 5 0 0 5 5 5 0 Anaphylotoxin-like domain DUF3744 PF12558.8 ORY50598.1 - 0.07 13.9 2.6 13 6.7 0.1 3.8 2 1 1 3 3 3 0 ATP-binding cassette cobalt transporter TPR_16 PF13432.6 ORY50598.1 - 0.075 13.7 0.0 9.4 7.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF4919 PF16266.5 ORY50598.1 - 0.082 12.8 0.1 11 5.9 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4919) GIT1_C PF12205.8 ORY50599.1 - 0.051 13.7 0.0 0.082 13.0 0.0 1.3 1 0 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term Neural_ProG_Cyt PF06567.11 ORY50601.1 - 1.7e-19 70.2 14.8 6 7.1 0.0 11.5 1 1 11 12 12 12 11 Neural chondroitin sulphate proteoglycan cytoplasmic domain MRP-S24 PF14955.6 ORY50601.1 - 1.7e-15 57.1 0.0 58 3.7 0.0 11.5 1 1 11 12 12 12 0 Mitochondrial ribosome subunit S24 ARTD15_N PF18084.1 ORY50601.1 - 1.1e-14 54.5 15.7 25 5.2 0.0 11.2 1 1 10 11 11 11 10 ARTD15 N-terminal domain Bravo_FIGEY PF13882.6 ORY50601.1 - 2.9e-07 31.8 7.3 1.2e+02 4.1 0.0 8.2 1 1 10 11 11 11 0 Bravo-like intracellular region DUF1796 PF08795.10 ORY50604.1 - 0.75 9.7 2.9 0.67 9.9 0.3 2.2 2 0 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) PRKG1_interact PF15898.5 ORY50605.1 - 0.0098 16.8 8.4 0.0098 16.8 8.4 2.9 2 0 0 2 2 2 1 cGMP-dependent protein kinase interacting domain Prp19 PF08606.11 ORY50605.1 - 0.033 14.2 1.1 0.074 13.1 1.1 1.6 1 0 0 1 1 1 0 Prp19/Pso4-like DUF4196 PF13846.6 ORY50605.1 - 0.18 12.0 7.2 1.2 9.4 7.2 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4196) HMG_box PF00505.19 ORY50693.1 - 1.8e-19 69.9 0.8 2.2e-19 69.6 0.8 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY50693.1 - 2.7e-05 24.7 0.1 3.1e-05 24.5 0.1 1.1 1 0 0 1 1 1 1 HMG-box domain Glutaredoxin PF00462.24 ORY50694.1 - 2.7e-32 110.8 0.0 1.1e-17 63.9 0.0 3.0 3 0 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.20 ORY50694.1 - 5e-14 52.1 0.2 1.3e-13 50.8 0.2 1.6 1 0 0 1 1 1 1 Thioredoxin ZinT PF09223.11 ORY50694.1 - 0.01 15.7 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment OST3_OST6 PF04756.13 ORY50694.1 - 0.018 14.4 0.2 0.026 13.9 0.2 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Phosducin PF02114.16 ORY50694.1 - 0.03 13.3 0.0 0.059 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosducin EF-hand_13 PF17958.1 ORY50694.1 - 0.051 13.4 0.0 9.4 6.1 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain SH3BGR PF04908.15 ORY50694.1 - 0.058 13.6 0.0 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein Thioredoxin_8 PF13905.6 ORY50694.1 - 0.078 13.3 0.4 0.77 10.1 0.1 2.7 2 1 1 3 3 3 0 Thioredoxin-like KIAA1430 PF13879.6 ORY50695.1 - 1.7e-17 64.0 12.1 1.7e-17 64.0 12.1 3.0 3 1 1 4 4 4 1 KIAA1430 homologue AlphaC_C PF17480.2 ORY50695.1 - 0.0097 15.9 2.3 0.01 15.8 0.2 2.1 2 0 0 2 2 2 1 AlphaC C-terminal Ribosomal_L27A PF00828.19 ORY50696.1 - 1.9e-19 70.6 0.0 2.7e-19 70.1 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Tcp11 PF05794.13 ORY50698.1 - 4.7e-83 279.7 0.2 6.3e-83 279.3 0.2 1.2 1 0 0 1 1 1 1 T-complex protein 11 DUF3037 PF11236.8 ORY50698.1 - 0.1 13.0 0.1 0.83 10.1 0.1 2.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) Glyco_transf_43 PF03360.16 ORY50699.1 - 4.9e-08 33.1 0.0 6.8e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 43 HLH PF00010.26 ORY50700.1 - 7e-11 41.9 0.3 1.7e-10 40.7 0.3 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyco_transf_43 PF03360.16 ORY50701.1 - 4.6e-08 33.1 0.0 7.1e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 43 Epimerase PF01370.21 ORY50702.1 - 1.1e-33 116.7 0.0 1.4e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY50702.1 - 3.4e-32 112.2 0.0 2.1e-31 109.6 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ORY50702.1 - 5.9e-11 41.9 0.0 9e-11 41.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ORY50702.1 - 3.6e-07 29.6 0.2 1.8e-06 27.3 0.1 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 ORY50702.1 - 7.1e-07 28.6 0.0 2.1e-06 27.1 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 ORY50702.1 - 0.00021 20.5 0.0 0.00035 19.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Dpy-30 PF05186.13 ORY50703.1 - 4e-05 23.2 0.2 0.00056 19.5 0.2 2.2 1 1 0 1 1 1 1 Dpy-30 motif Macoilin PF09726.9 ORY50703.1 - 0.25 9.9 9.6 0.31 9.5 9.6 1.1 1 0 0 1 1 1 0 Macoilin family Spem1 PF15670.5 ORY50703.1 - 0.55 9.8 7.9 0.079 12.5 4.2 1.6 2 0 0 2 2 2 0 Spermatid maturation protein 1 SelP_N PF04592.14 ORY50703.1 - 1.8 7.9 23.2 0.18 11.2 18.9 1.6 2 0 0 2 2 2 0 Selenoprotein P, N terminal region DUF1387 PF07139.11 ORY50703.1 - 3.1 7.4 10.6 5.5 6.6 10.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Abhydrolase_1 PF00561.20 ORY50704.1 - 1e-28 100.7 0.0 6.5e-28 98.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 ORY50704.1 - 5.4e-22 77.9 0.0 1.6e-21 76.4 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein Autoind_bind PF03472.15 ORY50704.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Autoinducer binding domain Glyco_transf_43 PF03360.16 ORY50705.1 - 0.00048 20.0 0.0 0.00078 19.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 43 MutH PF02976.15 ORY50705.1 - 0.062 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 DNA mismatch repair enzyme MutH Epimerase PF01370.21 ORY50706.1 - 4.3e-47 160.6 0.0 5.3e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY50706.1 - 2.5e-44 152.0 0.0 3.2e-44 151.7 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ORY50706.1 - 5.4e-23 81.4 0.0 7.6e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ORY50706.1 - 5.6e-15 55.2 0.1 5.5e-14 52.0 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 ORY50706.1 - 8.4e-11 41.5 0.4 4.3e-08 32.6 0.4 2.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 ORY50706.1 - 1.2e-08 35.0 0.0 1.9e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ORY50706.1 - 1.1e-07 31.2 0.0 1.7e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 ORY50706.1 - 0.00099 18.6 0.0 0.0023 17.4 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 ORY50706.1 - 0.011 15.3 0.0 0.025 14.1 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family Adeno_PV PF03910.13 ORY50706.1 - 0.011 14.4 0.7 0.017 13.8 0.7 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV DUF5605 PF18310.1 ORY50710.1 - 0.015 15.2 0.1 5.4 7.0 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF5605) DUF4810 PF16068.5 ORY50710.1 - 0.1 13.1 0.1 14 6.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) ECH_1 PF00378.20 ORY50712.1 - 2e-06 27.3 0.0 2.1e-06 27.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ETS_PEA3_N PF04621.13 ORY50712.1 - 0.18 11.7 0.0 0.18 11.7 0.0 1.0 1 0 0 1 1 1 0 PEA3 subfamily ETS-domain transcription factor N terminal domain CSN8_PSD8_EIF3K PF10075.9 ORY50713.1 - 4.5e-30 104.5 0.0 1.2e-29 103.1 0.0 1.6 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 ORY50713.1 - 0.00026 20.5 0.0 0.00039 19.9 0.0 1.3 1 1 0 1 1 1 1 SAC3/GANP family Golgin_A5 PF09787.9 ORY50714.1 - 0.00014 21.5 18.7 0.00014 21.5 18.7 2.4 1 1 1 2 2 2 1 Golgin subfamily A member 5 IFT20 PF14931.6 ORY50714.1 - 0.017 15.3 1.9 0.017 15.3 1.9 5.1 1 1 4 5 5 5 0 Intraflagellar transport complex B, subunit 20 DUF4200 PF13863.6 ORY50714.1 - 0.023 15.1 10.9 0.023 15.1 10.9 3.7 1 1 2 3 3 2 0 Domain of unknown function (DUF4200) Filament PF00038.21 ORY50714.1 - 0.12 11.9 41.7 0.35 10.4 6.7 3.2 1 1 0 2 2 2 0 Intermediate filament protein Tropomyosin PF00261.20 ORY50714.1 - 0.53 9.6 47.2 1.2 8.4 28.3 2.3 1 1 0 2 2 2 0 Tropomyosin DUF3584 PF12128.8 ORY50714.1 - 0.55 7.7 38.3 0.71 7.3 38.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2277 PF10041.9 ORY50714.1 - 0.7 10.3 4.2 10 6.5 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2277) FlaC_arch PF05377.11 ORY50714.1 - 1.5 9.3 22.4 3.3 8.2 0.2 6.5 3 2 5 8 8 8 0 Flagella accessory protein C (FlaC) Fez1 PF06818.15 ORY50714.1 - 1.8 9.0 42.8 0.44 11.0 19.3 3.4 1 1 2 3 3 3 0 Fez1 APG6_N PF17675.1 ORY50714.1 - 1.9 9.0 49.0 0.79 10.2 24.7 3.7 1 1 0 2 2 2 0 Apg6 coiled-coil region Spc7 PF08317.11 ORY50714.1 - 2.2 7.1 45.5 0.1 11.5 15.0 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein Imm3 PF14425.6 ORY50714.1 - 3.3 7.8 11.2 0.41 10.7 3.6 2.5 2 0 0 2 2 2 0 Immunity protein Imm3 Fib_alpha PF08702.10 ORY50714.1 - 5.9 7.1 31.3 0.62 10.3 3.6 3.4 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Prismane PF03063.20 ORY50714.1 - 6.5 5.3 10.7 0.87 8.2 5.8 2.0 1 1 1 2 2 2 0 Prismane/CO dehydrogenase family Glyco_hydro_15 PF00723.21 ORY50715.1 - 2.2e-134 448.6 0.0 3.4e-134 448.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 ILEI PF15711.5 ORY50715.1 - 2.5e-24 85.6 0.0 7.7e-24 84.0 0.0 1.9 1 0 0 1 1 1 1 Interleukin-like EMT inducer cNMP_binding PF00027.29 ORY50716.1 - 2.4e-125 408.9 16.5 3.7e-14 52.6 0.0 9.6 9 0 0 9 9 9 9 Cyclic nucleotide-binding domain OHCU_decarbox PF09349.10 ORY50716.1 - 0.00027 21.4 0.4 15 6.0 0.0 6.2 6 0 0 6 6 6 0 OHCU decarboxylase DUF3952 PF13130.6 ORY50716.1 - 0.024 14.8 1.0 1.5 9.1 0.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3952) Ribosomal_L16 PF00252.18 ORY50716.1 - 0.047 13.7 0.0 0.19 11.8 0.0 2.1 1 0 0 1 1 1 0 Ribosomal protein L16p/L10e TA0956 PF11513.8 ORY50716.1 - 0.052 13.8 2.1 0.48 10.7 0.1 3.6 3 0 0 3 3 3 0 Thermoplasma acidophilum protein TA0956 DUF4388 PF14332.6 ORY50716.1 - 0.061 13.6 0.1 10 6.4 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4388) DUF2383 PF09537.10 ORY50716.1 - 0.087 13.2 1.8 11 6.4 0.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) AcylCoA_dehyd_C PF12186.8 ORY50716.1 - 0.1 12.7 12.3 2.2 8.5 0.1 5.6 5 0 0 5 5 5 0 Acyl-CoA dehydrogenase C terminal TMEM192 PF14802.6 ORY50716.1 - 0.24 10.5 6.9 1.9 7.5 0.8 2.4 2 0 0 2 2 2 0 TMEM192 family UPF0242 PF06785.11 ORY50716.1 - 0.8 9.8 29.9 2.4 8.2 8.0 3.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Ribonuc_red_2_N PF08471.10 ORY50716.1 - 0.86 9.8 3.7 0.96 9.7 0.1 3.0 3 0 0 3 3 3 0 Class II vitamin B12-dependent ribonucleotide reductase DUF5442 PF17514.2 ORY50716.1 - 0.94 9.7 3.5 1.2e+02 3.0 0.0 4.9 5 0 0 5 5 4 0 Family of unknown function (DUF5442) Herpes_UL33 PF03581.13 ORY50716.1 - 1.6 9.1 3.6 5.2 7.5 0.2 3.3 3 0 0 3 3 3 0 Herpesvirus UL33-like protein FAP206 PF12018.8 ORY50716.1 - 7.3 6.0 15.8 5.3 6.5 2.7 3.5 3 1 0 3 3 3 0 Domain of unknown function Cupin_2 PF07883.11 ORY50716.1 - 9.5 6.0 7.8 28 4.5 0.1 4.1 4 0 0 4 4 4 0 Cupin domain cNMP_binding PF00027.29 ORY50717.1 - 4.3e-54 180.5 2.2 1.7e-20 72.9 0.0 3.3 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 ORY50717.1 - 8.8e-05 22.1 2.6 0.1 12.4 0.1 2.5 2 0 0 2 2 2 2 Cupin domain FEZ PF07763.13 ORY50717.1 - 0.0019 18.0 0.8 0.0019 18.0 0.8 2.8 4 0 0 4 4 4 1 FEZ-like protein Cupin_3 PF05899.12 ORY50717.1 - 0.0021 17.7 2.3 0.41 10.4 0.1 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF861) IMD PF08397.11 ORY50717.1 - 0.14 11.6 6.5 0.41 10.0 6.5 1.8 1 0 0 1 1 1 0 IRSp53/MIM homology domain TolA_bind_tri PF16331.5 ORY50717.1 - 2.9 8.0 10.1 1.7 8.8 6.6 2.3 1 1 1 2 2 2 0 TolA binding protein trimerisation AFG1_ATPase PF03969.16 ORY50718.1 - 1.1e-92 310.7 0.0 1.2e-87 294.2 0.0 2.3 1 1 0 2 2 2 2 AFG1-like ATPase AAA_22 PF13401.6 ORY50718.1 - 0.0029 17.9 0.0 0.019 15.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 ORY50718.1 - 0.013 15.9 0.0 0.066 13.6 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY50718.1 - 0.032 14.6 0.0 0.11 12.8 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 ORY50718.1 - 0.072 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.18 ORY50718.1 - 0.21 11.4 0.8 4.9 6.9 0.1 2.8 2 1 0 2 2 2 0 Bacterial dnaA protein PP2C PF00481.21 ORY50719.1 - 2.7e-64 217.3 0.2 3.5e-64 216.9 0.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Ribosomal_S10 PF00338.22 ORY50720.1 - 4.4e-30 103.8 0.5 5.6e-30 103.5 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e SNRNP27 PF08648.12 ORY50721.1 - 1.7e-05 24.8 0.3 3.2e-05 23.9 0.3 1.5 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins MLVIN_C PF18697.1 ORY50723.1 - 0.043 13.9 0.0 0.1 12.7 0.0 1.7 1 1 0 1 1 1 0 Murine leukemia virus (MLV) integrase (IN) C-terminal domain CH PF00307.31 ORY50725.1 - 1.2e-37 128.4 11.1 1.4e-19 70.3 0.1 3.2 4 0 0 4 4 4 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 ORY50725.1 - 7.5e-08 32.1 0.1 0.002 18.0 0.0 3.0 2 1 0 2 2 2 2 CAMSAP CH domain Init_tRNA_PT PF04179.12 ORY50725.1 - 0.032 14.5 0.1 0.032 14.5 0.1 3.9 4 1 0 4 4 4 0 Rit1 DUSP-like domain Hemerythrin PF01814.23 ORY50725.1 - 1.6 9.4 11.0 0.36 11.5 3.4 3.0 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain T2SSF PF00482.23 ORY50725.1 - 4.4 7.3 12.2 12 5.9 3.4 2.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Lyase_1 PF00206.20 ORY50726.1 - 3.5e-24 85.8 0.0 4.9e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 ORY50726.1 - 1.7e-14 54.1 0.0 5e-14 52.6 0.0 1.9 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.11 ORY50726.1 - 0.01 15.5 0.1 0.023 14.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) LIM PF00412.22 ORY50727.1 - 2.3e-06 27.7 1.9 2.3e-06 27.7 1.9 1.9 2 0 0 2 2 2 1 LIM domain HbrB PF08539.11 ORY50729.1 - 3e-34 118.4 0.7 1.8e-32 112.6 0.1 2.7 2 1 0 2 2 2 1 HbrB-like DUF5314 PF17241.2 ORY50729.1 - 0.012 15.3 0.4 0.021 14.5 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5314) Rad60-SLD_2 PF13881.6 ORY50730.1 - 3.1e-17 62.7 0.0 6.5e-17 61.6 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 ORY50730.1 - 0.021 14.6 0.0 0.1 12.4 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin family TmoB PF06234.12 ORY50730.1 - 0.11 12.6 0.5 2.4 8.3 0.0 2.3 2 1 0 2 2 2 0 Toluene-4-monooxygenase system protein B (TmoB) cNMP_binding PF00027.29 ORY50731.1 - 9.8e-48 160.2 1.4 3.6e-16 59.0 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain DUF1057 PF06342.12 ORY50731.1 - 0.016 14.2 0.6 0.035 13.1 0.6 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Bac_RepA_C PF18008.1 ORY50731.1 - 0.2 12.0 4.1 10 6.6 0.1 3.7 4 0 0 4 4 4 0 Replication initiator protein A C-terminal domain IL6 PF00489.17 ORY50731.1 - 2.8 7.5 7.3 1.5 8.3 1.3 2.7 3 0 0 3 3 3 0 Interleukin-6/G-CSF/MGF family Cnd3 PF12719.7 ORY50732.1 - 0.022 14.0 1.1 0.03 13.5 1.0 1.3 1 1 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.7 ORY50732.1 - 0.023 14.8 0.3 0.052 13.6 0.1 1.7 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORY50732.1 - 0.037 14.3 0.1 0.55 10.6 0.1 2.6 2 0 0 2 2 2 0 HEAT repeat HEAT_EZ PF13513.6 ORY50732.1 - 0.11 13.0 0.1 0.25 11.9 0.1 1.6 1 0 0 1 1 1 0 HEAT-like repeat WD40 PF00400.32 ORY50733.1 - 9e-12 45.3 0.5 0.0057 17.5 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat cNMP_binding PF00027.29 ORY50734.1 - 7.9e-21 73.9 0.0 1.2e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 ORY50734.1 - 0.044 13.5 0.1 0.07 12.8 0.1 1.3 1 0 0 1 1 1 0 Cupin domain DUF2935 PF11155.8 ORY50736.1 - 0.04 14.3 1.0 0.069 13.5 1.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) ACT PF01842.25 ORY50736.1 - 0.18 11.6 0.3 4.6 7.1 0.2 2.3 2 0 0 2 2 2 0 ACT domain DLIC PF05783.11 ORY50737.1 - 5.3e-44 150.8 6.8 1.4e-33 116.5 0.0 3.0 2 1 1 3 3 3 3 Dynein light intermediate chain (DLIC) UDPG_MGDP_dh_N PF03721.14 ORY50738.1 - 2.3e-64 216.4 0.0 4.2e-64 215.6 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 ORY50738.1 - 1.6e-33 115.2 0.0 5.7e-33 113.5 0.1 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 ORY50738.1 - 4.3e-31 107.0 0.0 9e-31 105.9 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain Sacchrp_dh_NADP PF03435.18 ORY50738.1 - 0.0089 16.3 0.0 0.15 12.3 0.0 2.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 ORY50738.1 - 0.069 13.3 0.0 2 8.6 0.0 3.0 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase GCHY-1 PF02649.14 ORY50738.1 - 0.34 10.4 1.8 2.3 7.7 0.3 2.4 2 1 1 3 3 3 0 Type I GTP cyclohydrolase folE2 CHORD PF04968.12 ORY50739.1 - 3.2e-52 175.1 20.8 4.7e-27 94.5 5.1 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.16 ORY50739.1 - 7.3e-15 55.7 0.0 1.2e-14 55.1 0.0 1.3 1 0 0 1 1 1 1 CS domain Rep_fac-A_C PF08646.10 ORY50739.1 - 0.061 13.1 0.6 0.17 11.6 0.6 1.7 1 0 0 1 1 1 0 Replication factor-A C terminal domain TFIIA PF03153.13 ORY50740.1 - 0.12 12.4 14.8 0.056 13.4 12.7 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hamartin PF04388.12 ORY50740.1 - 7.4 5.1 21.3 9.4 4.8 21.3 1.0 1 0 0 1 1 1 0 Hamartin protein PCAF_N PF06466.11 ORY50741.1 - 0.018 14.6 0.1 0.02 14.5 0.1 1.1 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain cNMP_binding PF00027.29 ORY50742.1 - 2.5e-34 117.2 2.6 6.9e-19 67.7 0.0 3.6 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain WWE PF02825.20 ORY50742.1 - 0.037 14.6 0.3 0.12 13.0 0.1 2.0 2 0 0 2 2 2 0 WWE domain DUF2304 PF10066.9 ORY50742.1 - 1.7 8.9 4.1 0.8 10.0 0.3 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Histone PF00125.24 ORY50743.1 - 3.3e-21 76.0 0.2 4.4e-21 75.6 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY50743.1 - 2.6e-06 27.6 0.1 5.9e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 ORY50743.1 - 0.00015 22.2 0.0 0.00025 21.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1931 PF09123.11 ORY50743.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) Histone_H2A_C PF16211.5 ORY50744.1 - 2.3e-19 68.8 0.7 5e-19 67.7 0.7 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 ORY50744.1 - 4.5e-16 59.4 0.0 5.8e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY50744.1 - 3.2e-05 24.1 0.0 4.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone UPF0029 PF01205.19 ORY50745.1 - 1.9e-30 105.3 0.0 2.7e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 ORY50745.1 - 2.1e-07 31.2 0.2 1.3e-05 25.5 0.2 2.2 1 1 0 1 1 1 1 RWD domain XPG_I_2 PF12813.7 ORY50745.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 XPG domain containing RNA_pol_A_bac PF01000.26 ORY50746.1 - 1e-23 83.8 0.0 2.4e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 ORY50746.1 - 1.8e-22 78.6 0.0 2.8e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain WD40 PF00400.32 ORY50747.1 - 3.9e-08 33.8 1.0 4e-05 24.3 0.3 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY50747.1 - 4.2e-06 27.0 0.0 0.16 12.3 0.0 5.0 4 2 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Med8 PF10232.9 ORY50748.1 - 0.026 14.1 1.5 0.055 13.0 1.5 1.7 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 PK PF00224.21 ORY50749.1 - 1.8e-100 336.2 4.5 2.3e-100 335.9 4.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 ORY50749.1 - 3.4e-22 78.9 1.2 7.6e-22 77.7 0.2 2.0 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 ORY50749.1 - 0.033 13.3 0.3 0.3 10.2 0.0 2.2 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family R-HINP1I PF11463.8 ORY50749.1 - 0.056 12.9 0.3 0.092 12.2 0.3 1.3 1 0 0 1 1 1 0 R.HinP1I restriction endonuclease Metallophos PF00149.28 ORY50750.1 - 4e-40 138.5 0.1 5.4e-40 138.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORY50750.1 - 1.4e-22 79.9 0.8 2.3e-22 79.1 0.2 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Importin_rep PF18773.1 ORY50750.1 - 0.23 11.2 0.8 0.96 9.2 0.0 2.4 2 0 0 2 2 2 0 Importin 13 repeat Metallophos PF00149.28 ORY50751.1 - 1.2e-38 133.6 0.2 1.6e-38 133.3 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 ORY50751.1 - 2.1e-18 66.5 0.1 4.5e-18 65.4 0.1 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain MFS_2 PF13347.6 ORY50752.1 - 2.9e-10 39.3 5.3 4e-10 38.8 5.3 1.3 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 ORY50752.1 - 2.9e-05 23.1 9.9 0.00011 21.3 9.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1118 PF06549.12 ORY50752.1 - 0.018 15.3 1.0 0.035 14.4 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1118) CBFD_NFYB_HMF PF00808.23 ORY50754.1 - 5.2e-18 65.1 0.0 8.8e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 ORY50754.1 - 0.0033 17.6 0.1 0.0058 16.8 0.1 1.4 1 0 0 1 1 1 1 CENP-W protein COPI_C PF06957.11 ORY50755.1 - 1.4e-138 462.0 0.0 2e-138 461.5 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 ORY50755.1 - 1.2e-136 456.3 0.0 2e-136 455.6 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 ORY50755.1 - 1.8e-46 155.1 12.8 5.9e-09 36.4 0.7 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY50755.1 - 3.2e-11 43.4 0.3 9.4e-06 25.8 0.0 5.5 4 1 3 7 7 7 1 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 ORY50755.1 - 0.044 13.8 1.1 0.062 13.3 0.0 1.9 2 0 0 2 2 2 0 LisH Fis1_TPR_C PF14853.6 ORY50755.1 - 0.063 13.4 0.2 0.18 11.9 0.2 1.7 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.6 ORY50755.1 - 0.77 10.7 5.0 69 4.7 0.1 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat Nup160 PF11715.8 ORY50755.1 - 1 7.9 3.8 5.6 5.5 0.0 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Ribosomal_L29e PF01779.17 ORY50756.1 - 5.9e-24 84.1 13.4 7.4e-24 83.8 13.4 1.1 1 0 0 1 1 1 1 Ribosomal L29e protein family Kelch_4 PF13418.6 ORY50758.1 - 1.4e-28 98.6 2.7 5.8e-06 26.2 0.0 6.4 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 ORY50758.1 - 1.9e-22 79.0 0.3 2.4e-07 30.9 0.0 6.1 5 1 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 ORY50758.1 - 9.9e-18 63.7 3.7 1.7e-05 24.7 0.1 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 ORY50758.1 - 1e-16 60.1 11.7 0.00055 19.8 0.2 6.3 6 1 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 ORY50758.1 - 1.2e-16 60.3 4.5 5.5e-05 23.3 0.0 6.2 4 1 2 6 6 6 4 Kelch motif Kelch_1 PF01344.25 ORY50758.1 - 4.6e-12 45.3 2.7 6.9e-05 22.3 0.1 5.3 5 0 0 5 5 5 3 Kelch motif LegC3_N PF18654.1 ORY50758.1 - 5.8 6.1 14.3 9.5 5.4 14.3 1.3 1 0 0 1 1 1 0 LegC3 N-terminal coiled-coil domain MCM PF00493.23 ORY50759.1 - 1.3e-84 282.8 0.0 1.9e-84 282.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY50759.1 - 4.2e-25 88.0 0.8 8.8e-25 87.0 0.8 1.5 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 ORY50759.1 - 2.4e-08 33.6 0.0 2.6e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ORY50759.1 - 1.2e-06 28.6 0.0 5.3e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM_lid PF17855.1 ORY50759.1 - 1.8e-06 28.3 4.9 0.00023 21.5 1.1 2.5 1 1 1 2 2 2 2 MCM AAA-lid domain AAA_3 PF07726.11 ORY50759.1 - 0.00018 21.4 0.1 0.0012 18.7 0.0 2.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY50759.1 - 0.0058 17.0 0.4 0.057 13.8 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 ORY50759.1 - 0.01 16.2 0.0 0.037 14.4 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 ORY50759.1 - 0.024 14.4 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain FtsK_SpoIIIE PF01580.18 ORY50759.1 - 0.034 13.5 0.0 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_7 PF12775.7 ORY50759.1 - 0.063 12.8 0.0 0.2 11.1 0.0 1.8 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 ORY50759.1 - 0.083 12.6 0.0 0.72 9.5 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.6 ORY50759.1 - 0.14 12.4 0.1 1.4 9.2 0.1 2.4 1 1 0 1 1 1 0 AAA domain Chromate_transp PF02417.15 ORY50760.1 - 3.6e-61 205.9 44.6 5.3e-38 130.6 18.8 2.7 3 0 0 3 3 3 2 Chromate transporter GTP_EFTU PF00009.27 ORY50761.1 - 1.1e-35 123.0 1.5 5.4e-34 117.4 1.5 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 ORY50761.1 - 6.8e-29 100.1 0.0 2.1e-28 98.5 0.0 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 ORY50761.1 - 2.9e-09 37.0 0.2 6.1e-09 36.0 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 ORY50761.1 - 2.4e-06 27.8 0.1 0.0029 17.9 0.0 2.8 2 0 0 2 2 2 2 Elongation factor Tu domain 2 FeoB_N PF02421.18 ORY50761.1 - 0.002 17.7 0.0 0.0073 15.8 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 ORY50761.1 - 0.0034 16.8 0.1 0.0034 16.8 0.1 2.5 3 1 0 3 3 3 1 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.6 ORY50761.1 - 0.013 15.4 0.3 0.16 11.9 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu domain 4 RsgA_GTPase PF03193.16 ORY50761.1 - 0.067 13.1 0.8 3.9 7.4 0.0 2.6 1 1 1 2 2 2 0 RsgA GTPase RP-C_C PF11800.8 ORY50761.1 - 6.8 6.7 7.2 9.7 6.2 1.4 2.4 2 0 0 2 2 2 0 Replication protein C C-terminal region ATG16 PF08614.11 ORY50762.1 - 5.8e-34 118.1 27.4 9.4e-34 117.4 27.4 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) WD40 PF00400.32 ORY50762.1 - 5.4e-29 99.8 19.9 2.8e-05 24.8 0.5 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY50762.1 - 1.7e-11 44.2 3.6 0.2 12.0 0.0 5.7 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY50762.1 - 1.2e-05 24.2 11.1 0.067 11.8 0.1 4.7 1 1 4 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.11 ORY50762.1 - 5.9e-05 23.0 0.6 3.8 7.4 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY50762.1 - 7e-05 22.3 3.5 1.9 7.7 0.0 3.2 1 1 2 3 3 3 3 WD40-like domain Ge1_WD40 PF16529.5 ORY50762.1 - 8e-05 21.7 1.1 0.29 10.0 0.0 3.4 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORY50762.1 - 0.0016 17.0 0.3 0.0045 15.6 0.1 1.8 2 0 0 2 2 2 1 Cytochrome D1 heme domain Flagellar_rod PF05149.12 ORY50762.1 - 0.016 14.7 22.5 0.31 10.5 21.8 2.2 1 1 0 1 1 1 0 Paraflagellar rod protein YabA PF06156.13 ORY50762.1 - 4.9 7.9 15.7 6.8 7.4 5.8 2.8 1 1 1 2 2 2 0 Initiation control protein YabA Rhomboid PF01694.22 ORY50763.1 - 7.1e-05 22.9 0.9 0.00016 21.7 0.9 1.6 1 0 0 1 1 1 1 Rhomboid family Transcrip_reg PF01709.20 ORY50763.1 - 0.074 12.5 0.5 0.12 11.8 0.5 1.2 1 0 0 1 1 1 0 Transcriptional regulator Cwf_Cwc_15 PF04889.12 ORY50763.1 - 0.49 10.1 5.0 0.74 9.5 5.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein XPG_N PF00752.17 ORY50765.1 - 1.5e-26 92.8 0.0 3.2e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 ORY50765.1 - 1.4e-22 79.9 0.1 5.7e-22 77.9 0.0 2.0 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 ORY50765.1 - 4.3e-05 23.1 0.2 8.8e-05 22.1 0.1 1.5 1 1 0 1 1 1 1 XPG domain containing 5_3_exonuc_N PF02739.16 ORY50765.1 - 0.0039 17.1 0.1 0.013 15.4 0.1 1.7 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain Pox_G5 PF04599.12 ORY50765.1 - 0.0065 15.5 0.1 1.5 7.7 0.0 2.1 2 0 0 2 2 2 2 Poxvirus G5 protein TPR_8 PF13181.6 ORY50765.1 - 0.06 13.6 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Matrilin_ccoil PF10393.9 ORY50766.1 - 0.0039 17.0 4.0 0.0042 16.9 0.7 2.2 2 0 0 2 2 2 1 Trimeric coiled-coil oligomerisation domain of matrilin TRAF_BIRC3_bd PF16673.5 ORY50766.1 - 0.0091 15.8 0.8 0.31 10.9 0.1 2.6 1 1 2 3 3 2 1 TNF receptor-associated factor BIRC3 binding domain GD_AH_C PF04295.13 ORY50766.1 - 0.087 11.6 0.1 0.11 11.2 0.1 1.0 1 0 0 1 1 1 0 D-galactarate dehydratase / Altronate hydrolase, C terminus HSBP1 PF06825.12 ORY50766.1 - 0.11 12.4 4.1 0.12 12.2 1.3 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Hydrolase_6 PF13344.6 ORY50767.1 - 1.9e-29 101.7 0.0 3.7e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY50767.1 - 1.9e-22 79.1 0.0 4e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 ORY50767.1 - 5.2e-12 46.5 0.1 4.2e-11 43.5 0.1 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 ORY50767.1 - 5e-10 39.7 0.1 2.4e-05 24.5 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 ORY50767.1 - 0.00066 19.3 0.1 0.27 10.8 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial PGP phosphatase DUF1672 PF07901.11 ORY50767.1 - 0.027 13.8 0.2 0.04 13.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) Aminotran_1_2 PF00155.21 ORY50768.1 - 4.1e-60 203.9 0.0 4.6e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ORY50768.1 - 0.0019 16.8 0.0 0.0036 15.9 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 ORY50768.1 - 0.051 12.5 0.0 0.17 10.8 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class-V Alliinase_C PF04864.13 ORY50768.1 - 0.19 10.6 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Allinase Kinesin PF00225.23 ORY50769.1 - 4.2e-54 183.7 0.7 6.8e-54 183.0 0.7 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY50769.1 - 3.9e-20 72.3 0.7 9.9e-20 71.0 0.2 1.9 2 0 0 2 2 2 1 Microtubule binding SAM_1 PF00536.30 ORY50769.1 - 2.5e-07 31.0 0.1 5.8e-07 29.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 ORY50769.1 - 2.7e-06 27.4 0.1 5.8e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HisG_C PF08029.11 ORY50769.1 - 0.14 12.4 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 HisG, C-terminal domain Sec15 PF04091.12 ORY50770.1 - 2.2e-79 267.2 2.6 2.4e-79 267.0 1.0 1.9 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like COG5 PF10392.9 ORY50770.1 - 0.0046 17.1 4.5 0.019 15.1 0.7 3.3 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Colicin_Pyocin PF01320.18 ORY50770.1 - 0.043 13.9 0.4 2.1 8.5 0.0 3.3 3 0 0 3 3 3 0 Colicin immunity protein / pyocin immunity protein DUF3510 PF12022.8 ORY50770.1 - 0.088 13.2 0.8 0.4 11.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) Sec5 PF15469.6 ORY50770.1 - 0.15 11.9 7.3 0.23 11.2 1.8 3.0 3 1 0 3 3 3 0 Exocyst complex component Sec5 COG2 PF06148.11 ORY50770.1 - 0.26 11.4 3.5 0.92 9.6 3.5 2.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.14 ORY50770.1 - 0.27 11.1 4.9 0.3 11.0 2.1 2.5 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain TetR_C_37 PF18665.1 ORY50770.1 - 0.32 11.6 4.8 0.82 10.3 0.0 3.9 4 1 1 5 5 5 0 Tetracyclin repressor-like, C-terminal domain Histone PF00125.24 ORY50771.1 - 3.3e-21 76.0 0.2 4.4e-21 75.6 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY50771.1 - 2.6e-06 27.6 0.1 5.9e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 ORY50771.1 - 0.00015 22.2 0.0 0.00025 21.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1931 PF09123.11 ORY50771.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) Histone PF00125.24 ORY50772.1 - 4.1e-11 43.3 0.0 2.5e-10 40.8 0.0 1.8 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 ORY50772.1 - 2e-06 27.4 0.4 4.6e-06 26.3 0.4 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Glycos_transf_1 PF00534.20 ORY50773.1 - 1.5e-34 119.0 0.0 4.8e-34 117.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 ORY50773.1 - 5.1e-15 56.1 0.0 1e-14 55.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 ORY50773.1 - 1.6e-08 34.7 0.0 2.7e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.6 ORY50773.1 - 3.1e-06 27.5 0.0 6.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 ORY50773.1 - 0.00017 22.1 0.0 0.00034 21.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_20 PF00982.21 ORY50773.1 - 0.007 15.1 0.0 0.0089 14.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Phosducin PF02114.16 ORY50774.1 - 5.1e-10 38.7 0.2 8.1e-10 38.1 0.2 1.3 1 0 0 1 1 1 1 Phosducin ThiF PF00899.21 ORY50775.1 - 4.1e-38 131.1 0.0 5.4e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 ORY50775.1 - 4.8e-05 23.6 2.5 0.00038 20.7 2.5 2.3 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 ORY50775.1 - 0.00034 20.8 0.1 0.00098 19.4 0.1 1.8 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.16 ORY50775.1 - 0.02 14.5 0.4 0.052 13.2 0.1 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 ORY50775.1 - 0.03 13.9 0.1 0.063 12.9 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 ORY50775.1 - 0.055 12.7 0.1 0.078 12.2 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 ORY50775.1 - 0.12 12.4 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NUSAP PF16006.5 ORY50776.1 - 0.17 11.6 4.7 0.033 14.0 0.8 1.8 2 0 0 2 2 2 0 Nucleolar and spindle-associated protein MMR_HSR1_C PF08438.10 ORY50777.1 - 0.16 12.5 0.0 0.3 11.7 0.0 1.4 1 1 0 1 1 1 0 GTPase of unknown function C-terminal UPF0029 PF01205.19 ORY50779.1 - 1.3e-29 102.6 0.0 1.7e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Endonuclea_NS_2 PF13930.6 ORY50780.1 - 0.052 13.7 0.1 0.084 13.0 0.1 1.3 1 0 0 1 1 1 0 DNA/RNA non-specific endonuclease Methyltransf_21 PF05050.12 ORY50781.1 - 4.4e-15 56.1 0.0 7.2e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_21 PF05050.12 ORY50782.1 - 1.2e-09 38.4 0.0 2.6e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase FkbM domain TehB PF03848.14 ORY50782.1 - 0.0044 16.5 0.0 0.0071 15.8 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_23 PF13489.6 ORY50782.1 - 0.0054 16.6 0.0 0.0069 16.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 ORY50782.1 - 0.16 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein DUF4209 PF13910.6 ORY50784.1 - 1.4e-16 60.5 0.7 2.8e-15 56.3 0.2 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4209) MGC-24 PF05283.11 ORY50785.1 - 0.082 13.4 2.3 0.095 13.1 2.3 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin zf-SNAP50_C PF12251.8 ORY50786.1 - 0.088 12.5 0.0 0.1 12.2 0.0 1.0 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal SCP_3 PF17844.1 ORY50791.1 - 0.094 12.5 0.2 0.16 11.8 0.2 1.4 1 0 0 1 1 1 0 Bacterial SCP ortholog Sporozoite_P67 PF05642.11 ORY50791.1 - 0.89 7.6 11.0 1.1 7.3 11.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Tir_receptor_C PF07489.11 ORY50791.1 - 3.9 7.4 15.0 7.5 6.5 15.0 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Mucin PF01456.17 ORY50791.1 - 4.3 7.3 25.7 0.96 9.4 22.6 1.5 2 0 0 2 2 2 0 Mucin-like glycoprotein AAA PF00004.29 ORY50793.1 - 2.3e-30 105.7 2.3 4.4e-29 101.6 2.3 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY50793.1 - 6.6e-09 35.4 0.1 1.5e-08 34.3 0.0 1.8 2 0 0 2 2 1 1 AAA+ lid domain Vps4_C PF09336.10 ORY50793.1 - 5.9e-08 32.6 0.0 2.3e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.6 ORY50793.1 - 6.6e-05 23.2 0.8 0.0014 18.9 0.8 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 ORY50793.1 - 0.00013 21.9 1.2 0.013 15.5 0.1 2.5 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY50793.1 - 0.00021 21.7 1.5 0.0065 16.9 1.5 2.7 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 ORY50793.1 - 0.00026 20.8 0.0 0.00048 19.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 ORY50793.1 - 0.00038 19.9 0.1 0.55 9.6 0.0 2.8 2 1 1 3 3 3 2 Bacterial TniB protein AAA_25 PF13481.6 ORY50793.1 - 0.0006 19.4 0.4 0.0078 15.8 0.3 2.4 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 ORY50793.1 - 0.0006 19.3 0.1 0.0014 18.1 0.1 1.6 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 ORY50793.1 - 0.0026 17.9 0.1 0.14 12.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 ORY50793.1 - 0.0028 17.2 0.0 0.013 15.0 0.0 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region ATPase PF06745.13 ORY50793.1 - 0.003 16.9 0.6 0.9 8.8 0.0 2.2 1 1 1 2 2 2 2 KaiC IstB_IS21 PF01695.17 ORY50793.1 - 0.0068 16.2 0.0 0.016 14.9 0.0 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.12 ORY50793.1 - 0.011 15.6 0.2 0.026 14.5 0.1 1.6 1 1 0 1 1 1 0 NACHT domain FCH PF00611.23 ORY50793.1 - 0.012 15.9 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain AAA_33 PF13671.6 ORY50793.1 - 0.018 15.2 0.1 0.036 14.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 ORY50793.1 - 0.022 14.9 0.0 0.044 13.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 ORY50793.1 - 0.036 13.8 0.0 0.16 11.6 0.1 2.1 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 ORY50793.1 - 0.037 13.5 0.0 0.082 12.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 ORY50793.1 - 0.038 13.7 0.0 0.24 11.1 0.0 2.0 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 ORY50793.1 - 0.043 14.4 0.0 0.088 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ORY50793.1 - 0.12 12.7 0.4 0.32 11.3 0.4 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY50793.1 - 0.15 12.5 0.0 0.3 11.5 0.0 1.6 1 1 0 1 1 1 0 RNA helicase PIG-H PF10181.9 ORY50794.1 - 5.9e-10 38.9 0.5 1.5e-09 37.6 0.5 1.7 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component FAM194 PF14977.6 ORY50794.1 - 0.014 14.7 0.7 0.025 13.9 0.4 1.5 2 0 0 2 2 2 0 FAM194 protein GATase_4 PF13230.6 ORY50794.1 - 0.11 11.3 0.0 0.62 8.9 0.0 1.9 2 0 0 2 2 2 0 Glutamine amidotransferases class-II DNA_pol_A_exo1 PF01612.20 ORY50796.1 - 2.4e-19 69.7 0.0 3.4e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease FAD_binding_7 PF03441.14 ORY50797.1 - 5.2e-74 248.1 0.1 7.5e-74 247.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 ORY50797.1 - 6.4e-38 130.3 0.0 1.5e-37 129.1 0.0 1.6 2 0 0 2 2 2 1 DNA photolyase PPTA PF01239.22 ORY50798.1 - 1.4e-16 59.6 2.2 0.00011 21.7 0.4 4.9 4 0 0 4 4 4 4 Protein prenyltransferase alpha subunit repeat TPR_2 PF07719.17 ORY50799.1 - 0.00044 20.1 1.9 0.078 13.1 0.5 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY50799.1 - 0.00077 19.7 0.8 0.0021 18.3 0.1 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY50799.1 - 0.004 16.9 3.9 0.023 14.5 0.7 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY50799.1 - 0.02 15.1 0.8 0.046 13.9 0.8 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 SPO22 PF08631.10 ORY50800.1 - 0.00037 20.1 0.0 0.00042 19.9 0.0 1.1 1 0 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like cNMP_binding PF00027.29 ORY50801.1 - 8.6e-42 141.1 0.1 3.1e-19 68.8 0.0 3.1 4 0 0 4 4 4 2 Cyclic nucleotide-binding domain Ion_trans PF00520.31 ORY50801.1 - 0.00045 19.5 9.8 0.00076 18.8 9.8 1.3 1 0 0 1 1 1 1 Ion transport protein Cupin_2 PF07883.11 ORY50801.1 - 0.0047 16.6 0.2 2.7 7.8 0.0 3.1 3 0 0 3 3 3 2 Cupin domain Cupin_3 PF05899.12 ORY50801.1 - 0.02 14.6 0.4 2.7 7.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF861) GST_N PF02798.20 ORY50801.1 - 0.12 12.8 0.0 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Methyltransf_21 PF05050.12 ORY50803.1 - 1.2e-07 32.0 0.0 1.3e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_21 PF05050.12 ORY50804.1 - 1.3e-12 48.1 0.0 2.3e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain BMF PF15185.6 ORY50804.1 - 0.0027 17.5 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 Bcl-2-modifying factor, apoptosis FAD_binding_7 PF03441.14 ORY50805.1 - 3.1e-51 173.7 0.6 4.7e-51 173.2 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 ORY50805.1 - 1.2e-16 61.2 0.0 1.7e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 DNA photolyase Alg6_Alg8 PF03155.15 ORY50806.1 - 6e-139 464.1 19.2 7e-139 463.9 19.2 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family EBV-NA1 PF02905.14 ORY50806.1 - 0.064 13.1 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain RRM_1 PF00076.22 ORY50807.1 - 4.8e-77 253.8 4.5 2.1e-18 65.9 0.0 5.9 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY50807.1 - 0.0004 20.4 0.0 5.6 7.2 0.0 4.3 4 0 0 4 4 4 1 RNA recognition motif Limkain-b1 PF11608.8 ORY50807.1 - 0.0031 17.6 0.1 0.94 9.6 0.0 4.5 3 1 1 4 4 4 1 Limkain b1 RRM_Rrp7 PF17799.1 ORY50807.1 - 0.0038 17.0 2.0 6.8 6.5 0.0 4.9 5 1 0 5 5 5 1 Rrp7 RRM-like N-terminal domain RRM_2 PF04059.12 ORY50807.1 - 0.017 15.3 0.2 2.2 8.6 0.0 3.5 4 0 0 4 4 4 0 RNA recognition motif 2 Nup35_RRM_2 PF14605.6 ORY50807.1 - 0.15 12.1 0.0 39 4.3 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif OB_RNB PF08206.11 ORY50807.1 - 0.21 11.3 1.6 23 4.8 0.3 3.0 2 0 0 2 2 2 0 Ribonuclease B OB domain GNAT_acetyltr_2 PF13718.6 ORY50807.1 - 0.71 9.2 0.0 0.71 9.2 0.0 3.2 4 0 0 4 4 4 0 GNAT acetyltransferase 2 Polysacc_synt_4 PF04669.13 ORY50808.1 - 4.2e-20 72.1 1.3 6.7e-18 64.9 1.3 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis Fcf1 PF04900.12 ORY50809.1 - 7.6e-31 106.4 0.0 1.2e-30 105.8 0.0 1.3 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 ORY50809.1 - 0.00043 20.6 0.0 0.0007 19.9 0.0 1.4 1 0 0 1 1 1 1 PIN like domain MT-A70 PF05063.14 ORY50810.1 - 1.2e-15 57.8 0.0 1.5e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 MT-A70 Dynamin_N PF00350.23 ORY50811.1 - 4.7e-06 26.8 0.0 0.00015 21.9 0.0 2.4 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 ORY50811.1 - 7.2e-05 22.8 0.0 0.00019 21.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY50811.1 - 0.023 14.6 0.1 7.4 6.4 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase Roc PF08477.13 ORY50811.1 - 0.065 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DNA_primase_S PF01896.19 ORY50811.1 - 0.2 11.7 0.3 0.75 9.8 0.1 2.0 3 0 0 3 3 3 0 DNA primase small subunit EXOSC1 PF10447.9 ORY50812.1 - 1.2e-18 67.6 1.9 3e-14 53.5 0.2 2.4 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 ORY50812.1 - 3.3e-09 36.4 1.8 9.8e-09 34.9 1.8 1.9 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region CD52 PF15116.6 ORY50812.1 - 0.13 12.4 1.3 0.25 11.4 1.3 1.5 1 0 0 1 1 1 0 CAMPATH-1 antigen CLASP_N PF12348.8 ORY50813.1 - 1.2e-22 80.7 0.0 1.4e-22 80.4 0.0 1.0 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 ORY50815.1 - 1.3e-12 46.8 7.7 0.003 17.7 0.0 6.6 7 0 0 7 7 6 3 HEAT repeat HEAT_2 PF13646.6 ORY50815.1 - 1e-09 38.7 0.1 5.2e-05 23.5 0.0 4.4 2 1 4 6 6 6 2 HEAT repeats Cohesin_HEAT PF12765.7 ORY50815.1 - 4.5e-07 30.0 3.3 0.027 14.8 0.0 4.0 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 ORY50815.1 - 1.7e-06 28.1 4.5 0.09 12.8 0.0 4.7 1 1 4 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Dopey_N PF04118.14 ORY50815.1 - 6e-06 25.6 0.5 0.00026 20.2 0.5 2.6 1 1 0 1 1 1 1 Dopey, N-terminal HEAT_EZ PF13513.6 ORY50815.1 - 1.3e-05 25.5 7.0 0.57 10.7 0.0 5.3 5 2 1 6 6 6 2 HEAT-like repeat DUF3361 PF11841.8 ORY50815.1 - 0.00028 20.9 1.0 0.082 12.8 0.9 3.3 2 1 2 4 4 4 1 Domain of unknown function (DUF3361) CLASP_N PF12348.8 ORY50815.1 - 0.00053 19.6 0.3 0.038 13.5 0.0 3.2 2 1 1 3 3 3 1 CLASP N terminal Vac14_Fab1_bd PF12755.7 ORY50815.1 - 0.0024 18.4 0.2 0.043 14.4 0.0 3.0 2 2 0 3 3 3 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 ORY50815.1 - 0.0036 17.5 0.2 0.28 11.4 0.0 2.8 2 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_C PF11698.8 ORY50815.1 - 0.036 14.2 0.1 4.2 7.5 0.0 2.6 2 0 0 2 2 2 0 V-ATPase subunit H TAF6_C PF07571.13 ORY50815.1 - 0.039 14.3 0.3 3.5 8.0 0.1 3.3 3 1 0 3 3 2 0 TAF6 C-terminal HEAT repeat domain Arm PF00514.23 ORY50815.1 - 1.5 9.0 4.2 5.3 7.2 0.0 3.9 4 1 1 5 5 5 0 Armadillo/beta-catenin-like repeat YCII PF03795.14 ORY50819.1 - 3e-07 30.8 0.0 3.8e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain RasGEF PF00617.19 ORY50820.1 - 1.7e-41 142.3 0.1 2.7e-39 135.2 0.1 2.7 1 1 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 ORY50820.1 - 1.3e-27 96.1 0.3 1.5e-26 92.7 0.2 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif WW PF00397.26 ORY50820.1 - 4.6e-15 55.4 2.7 6.4e-05 23.0 0.1 3.5 3 0 0 3 3 3 3 WW domain SH3_9 PF14604.6 ORY50820.1 - 3.2e-13 49.3 0.0 6.8e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY50820.1 - 1.5e-11 43.7 0.1 3e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY50820.1 - 5.4e-08 32.4 0.0 1.2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PQQ PF01011.21 ORY50820.1 - 0.0024 17.7 0.9 0.015 15.2 0.0 2.7 3 0 0 3 3 3 1 PQQ enzyme repeat Focal_AT PF03623.13 ORY50820.1 - 0.092 12.7 1.6 0.26 11.3 0.0 2.6 3 1 0 3 3 3 0 Focal adhesion targeting region MdcG PF10620.9 ORY50820.1 - 0.36 10.6 1.7 0.46 10.2 0.3 1.8 2 0 0 2 2 2 0 Phosphoribosyl-dephospho-CoA transferase MdcG PGM_PMM_I PF02878.16 ORY50821.1 - 3.7e-40 136.8 0.3 6.8e-40 136.0 0.3 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 ORY50821.1 - 7.1e-24 84.4 0.0 1.5e-23 83.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 ORY50821.1 - 5.3e-06 26.5 0.0 1.6e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 ORY50821.1 - 0.00011 22.4 0.0 0.00031 20.9 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Methyltransf_21 PF05050.12 ORY50822.1 - 1.7e-14 54.2 0.0 2.4e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_23 PF13489.6 ORY50822.1 - 0.016 15.1 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PWI PF01480.17 ORY50823.1 - 1.2e-25 89.6 0.0 2.1e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 PWI domain zf-MYND PF01753.18 ORY50824.1 - 1.8e-11 43.9 11.4 3.4e-11 43.0 11.4 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY50824.1 - 0.29 11.5 8.7 0.95 9.8 8.7 1.9 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 ORY50824.1 - 5.2 7.0 11.7 0.5 10.3 5.7 2.2 2 0 0 2 2 2 0 HIT zinc finger Sec2p PF06428.11 ORY50826.1 - 3e-11 43.1 13.2 7.5e-11 41.9 13.2 1.7 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p Filament PF00038.21 ORY50826.1 - 0.022 14.4 16.4 0.045 13.3 16.4 1.4 1 0 0 1 1 1 0 Intermediate filament protein Mob_Pre PF01076.19 ORY50826.1 - 0.024 14.5 4.2 0.043 13.6 3.7 1.6 1 1 0 1 1 1 0 Plasmid recombination enzyme Seryl_tRNA_N PF02403.22 ORY50826.1 - 0.35 11.1 14.6 1.2 9.4 10.4 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.6 ORY50826.1 - 0.39 10.0 8.9 0.047 13.0 4.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 ORY50826.1 - 0.9 9.0 14.5 35 3.8 14.5 2.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF2703 PF10865.8 ORY50826.1 - 1.5 9.1 4.9 0.56 10.4 1.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) DnaJ PF00226.31 ORY50827.1 - 3.3e-05 23.9 0.1 9.4e-05 22.5 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain DUF16 PF01519.16 ORY50827.1 - 0.054 14.0 1.0 0.054 14.0 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 DnaJ PF00226.31 ORY50828.1 - 1.1e-24 86.3 1.2 1.3e-24 86.0 1.2 1.1 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 ORY50828.1 - 0.0063 16.4 0.0 0.016 15.1 0.0 1.7 1 1 1 2 2 2 1 A repeated domain in UCH-protein GP38 PF05268.11 ORY50829.1 - 0.028 14.1 0.0 0.034 13.8 0.0 1.1 1 0 0 1 1 1 0 Phage tail fibre adhesin Gp38 GST_N PF02798.20 ORY50831.1 - 1.2e-13 51.2 0.1 2.8e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY50831.1 - 1.6e-13 50.7 0.4 4.2e-13 49.3 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY50831.1 - 0.00029 21.0 0.1 0.00061 20.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY50831.1 - 0.00067 19.6 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AvrM_N PF18247.1 ORY50831.1 - 0.041 13.8 0.0 1.6 8.7 0.0 2.6 2 0 0 2 2 2 0 Flax-rust effector AvrM N-terminal domain GST_N_4 PF17172.4 ORY50831.1 - 0.12 13.1 0.0 0.35 11.6 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain Amidohydro_2 PF04909.14 ORY50832.1 - 7.2e-63 213.1 0.0 8.4e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase LRR_4 PF12799.7 ORY50833.1 - 9.3e-14 51.3 40.4 0.0036 17.7 3.2 7.6 3 2 4 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY50833.1 - 3.8e-08 33.0 35.0 0.0036 17.0 1.1 6.2 2 2 6 8 8 8 6 Leucine rich repeat Pox_A32 PF04665.12 ORY50833.1 - 0.056 12.9 3.5 0.03 13.8 1.3 1.5 2 0 0 2 2 2 0 Poxvirus A32 protein LRR_9 PF14580.6 ORY50833.1 - 0.17 11.4 17.2 0.17 11.4 1.6 3.8 1 1 3 4 4 4 0 Leucine-rich repeat Methyltransf_16 PF10294.9 ORY50834.1 - 2.6e-15 56.6 0.0 3.7e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase FAM86 PF14904.6 ORY50834.1 - 8.9e-08 32.1 0.0 2.1e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function PrmA PF06325.13 ORY50834.1 - 0.00015 21.3 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 ORY50834.1 - 0.00056 19.5 0.0 0.00082 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 ORY50834.1 - 0.0099 16.6 0.0 0.019 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 ORY50834.1 - 0.014 14.8 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_25 PF13649.6 ORY50834.1 - 0.019 15.7 0.1 0.044 14.5 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 ORY50834.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF1479 PF07350.12 ORY50835.1 - 0.00066 18.5 0.0 0.00083 18.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) DUF5585 PF17823.1 ORY50835.1 - 0.0011 18.0 6.1 0.0015 17.6 6.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5585) Ustilago_mating PF05722.12 ORY50835.1 - 1.7 8.1 5.8 2.8 7.4 5.8 1.2 1 0 0 1 1 1 0 Ustilago B locus mating-type protein Dicty_CAR PF05462.11 ORY50836.1 - 0.0023 17.1 2.2 0.0026 17.0 2.2 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Git3 PF11710.8 ORY50836.1 - 0.0029 17.4 5.0 0.0034 17.2 5.0 1.2 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 ORY50837.1 - 0.05 12.9 1.5 0.091 12.1 0.3 1.8 1 1 1 2 2 2 0 7 transmembrane receptor (rhodopsin family) Sec3_C_2 PF15278.6 ORY50837.1 - 0.12 12.7 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Sec3 exocyst complex subunit CoA_transf_3 PF02515.17 ORY50838.1 - 2.3e-41 142.1 0.0 4.6e-41 141.2 0.0 1.4 1 1 0 1 1 1 1 CoA-transferase family III Peptidase_M17 PF00883.21 ORY50839.1 - 1.6e-121 405.4 0.0 2.2e-121 404.9 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 ORY50839.1 - 8.9e-10 38.5 3.1 2.4e-09 37.1 3.1 1.7 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain GCH_III PF05165.12 ORY50839.1 - 0.12 11.6 0.1 4.4 6.5 0.2 2.3 2 0 0 2 2 2 0 GTP cyclohydrolase III CRT10 PF08728.10 ORY50840.1 - 7.4e-07 27.7 0.0 0.00096 17.5 0.0 2.2 2 0 0 2 2 2 2 CRT10 WD40 PF00400.32 ORY50840.1 - 3e-05 24.7 0.4 0.00011 22.8 0.0 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY50840.1 - 0.0096 16.2 0.0 0.042 14.2 0.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain IU_nuc_hydro PF01156.19 ORY50841.1 - 5.3e-68 229.8 0.0 6.1e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase zinc_ribbon_5 PF13719.6 ORY50841.1 - 0.17 11.6 0.1 0.34 10.7 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain PPR_2 PF13041.6 ORY50843.1 - 0.022 15.0 0.2 0.55 10.5 0.0 2.6 1 1 1 2 2 2 0 PPR repeat family FHIPEP PF00771.20 ORY50843.1 - 0.071 11.6 0.0 0.095 11.2 0.0 1.1 1 0 0 1 1 1 0 FHIPEP family PPR PF01535.20 ORY50843.1 - 0.18 12.1 0.1 9 6.8 0.1 2.6 2 0 0 2 2 2 0 PPR repeat PhageMin_Tail PF10145.9 ORY50844.1 - 0.043 13.7 11.4 1.5 8.6 9.8 2.0 1 1 1 2 2 2 0 Phage-related minor tail protein Histone_H2A_C PF16211.5 ORY50845.1 - 2.2e-19 68.9 0.7 4.3e-19 67.9 0.7 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 ORY50845.1 - 3.4e-10 40.4 0.0 5.4e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone PF00125.24 ORY50846.1 - 2.6e-10 40.7 2.7 1.6e-08 35.0 2.7 2.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Aa_trans PF01490.18 ORY50847.1 - 4.1e-74 249.7 38.2 5e-74 249.4 38.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Herpes_UL14 PF03580.14 ORY50848.1 - 0.012 15.9 1.9 0.018 15.3 0.3 2.0 1 1 0 2 2 2 0 Herpesvirus UL14-like protein U-box PF04564.15 ORY50849.1 - 2.1e-13 50.2 0.1 4.6e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 ORY50849.1 - 1.3e-05 24.9 0.1 4e-05 23.4 0.0 2.0 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 ORY50849.1 - 0.0016 18.5 0.0 0.015 15.4 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 ORY50849.1 - 0.0019 18.2 0.0 0.0042 17.1 0.0 1.6 1 1 0 1 1 1 1 RING-type zinc-finger Tropomyosin_1 PF12718.7 ORY50849.1 - 0.0086 16.2 0.6 0.013 15.7 0.6 1.3 1 0 0 1 1 1 1 Tropomyosin like DUF5357 PF17310.2 ORY50849.1 - 0.017 13.7 0.1 0.019 13.5 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5357) zf-C3HC4_4 PF15227.6 ORY50849.1 - 0.17 12.1 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING U-box PF04564.15 ORY50850.1 - 7.3e-09 35.7 0.0 3.8e-06 27.0 0.0 2.1 2 0 0 2 2 2 2 U-box domain zf-NOSIP PF15906.5 ORY50850.1 - 0.0026 17.9 0.0 0.0036 17.4 0.0 1.2 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 ORY50850.1 - 0.027 14.3 0.1 0.057 13.2 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit ELO PF01151.18 ORY50852.1 - 3.9e-56 190.4 20.7 4.7e-56 190.1 20.7 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family COX7C PF02935.16 ORY50852.1 - 1.1 9.6 6.9 0.66 10.3 0.6 3.1 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIIc AAA PF00004.29 ORY50853.1 - 7.5e-50 168.8 0.0 1.5e-40 138.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY50853.1 - 4.2e-12 46.8 1.5 0.0032 17.9 0.1 4.6 3 1 0 4 4 4 2 AAA ATPase domain AAA_lid_3 PF17862.1 ORY50853.1 - 7.6e-12 44.8 0.0 0.0001 22.0 0.0 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_22 PF13401.6 ORY50853.1 - 4.4e-10 40.0 1.5 0.013 15.8 0.0 4.5 3 1 2 5 5 5 2 AAA domain IstB_IS21 PF01695.17 ORY50853.1 - 5.8e-07 29.4 0.0 0.037 13.8 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein ABC_tran PF00005.27 ORY50853.1 - 1.2e-06 29.0 0.0 0.022 15.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_7 PF12775.7 ORY50853.1 - 1.3e-06 28.1 0.0 0.012 15.2 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region RsgA_GTPase PF03193.16 ORY50853.1 - 2.8e-06 27.4 0.3 0.0087 16.0 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_14 PF13173.6 ORY50853.1 - 3.5e-06 27.1 0.0 0.00068 19.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY50853.1 - 8.6e-06 26.3 0.1 0.044 14.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.13 ORY50853.1 - 1.1e-05 24.7 0.0 0.028 13.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) RNA_helicase PF00910.22 ORY50853.1 - 1.3e-05 25.5 0.1 0.031 14.7 0.0 2.8 2 0 0 2 2 2 1 RNA helicase Sigma54_activat PF00158.26 ORY50853.1 - 1.8e-05 24.5 0.0 0.045 13.5 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_29 PF13555.6 ORY50853.1 - 2.8e-05 23.8 0.0 0.03 14.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain ATPase_2 PF01637.18 ORY50853.1 - 5.9e-05 23.1 0.2 0.16 11.9 0.1 3.0 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 ORY50853.1 - 8.3e-05 22.4 0.6 0.033 13.9 0.1 2.7 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.14 ORY50853.1 - 8.5e-05 22.6 1.4 0.011 15.8 0.2 3.4 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 ORY50853.1 - 0.00011 22.4 0.0 0.008 16.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Guanylate_kin PF00625.21 ORY50853.1 - 0.00026 20.7 1.0 3.4 7.3 0.0 4.2 3 1 1 4 4 4 1 Guanylate kinase T2SSE PF00437.20 ORY50853.1 - 0.00027 20.1 0.1 0.022 13.9 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.6 ORY50853.1 - 0.00043 20.5 0.0 0.15 12.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 ORY50853.1 - 0.00066 19.7 0.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 ORY50853.1 - 0.0027 17.0 0.1 0.69 9.1 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 ORY50853.1 - 0.0028 17.6 1.9 1.6 8.7 0.2 3.0 2 1 1 3 3 3 1 NACHT domain Mg_chelatase PF01078.21 ORY50853.1 - 0.0045 16.4 0.5 0.13 11.7 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.18 ORY50853.1 - 0.0049 16.7 0.0 1.6 8.5 0.0 2.7 2 1 0 2 2 2 1 Bacterial dnaA protein TIP49 PF06068.13 ORY50853.1 - 0.0054 16.0 0.1 0.039 13.2 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain Rad17 PF03215.15 ORY50853.1 - 0.0057 16.6 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain Adeno_IVa2 PF02456.15 ORY50853.1 - 0.0092 14.8 1.0 1 8.1 0.1 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein MMR_HSR1 PF01926.23 ORY50853.1 - 0.01 15.9 0.6 0.15 12.2 0.3 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AFG1_ATPase PF03969.16 ORY50853.1 - 0.014 14.3 0.0 3.2 6.5 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase NB-ARC PF00931.22 ORY50853.1 - 0.016 14.4 0.0 2.9 7.0 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain RuvB_N PF05496.12 ORY50853.1 - 0.017 14.9 0.0 0.19 11.5 0.0 2.6 3 0 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain Viral_helicase1 PF01443.18 ORY50853.1 - 0.018 14.8 0.0 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 ORY50853.1 - 0.022 14.1 0.1 4.6 6.5 0.0 2.4 2 0 0 2 2 2 0 KaiC TniB PF05621.11 ORY50853.1 - 0.022 14.2 0.1 6.2 6.2 0.0 3.3 4 0 0 4 4 3 0 Bacterial TniB protein AAA_28 PF13521.6 ORY50853.1 - 0.026 14.8 0.1 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 ORY50853.1 - 0.042 13.8 0.1 0.37 10.7 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.6 ORY50853.1 - 0.05 13.2 0.1 2.9 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 ORY50853.1 - 0.054 12.8 0.2 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.9 ORY50853.1 - 0.075 12.8 0.1 2.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.14 ORY50853.1 - 0.093 11.9 0.0 5.9 6.0 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain AAA_19 PF13245.6 ORY50853.1 - 0.1 12.9 0.1 2.3 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 ORY50853.1 - 0.12 11.7 0.1 4.7 6.6 0.0 2.5 2 1 0 3 3 2 0 RecF/RecN/SMC N terminal domain TrwB_AAD_bind PF10412.9 ORY50853.1 - 0.13 11.1 0.4 0.8 8.5 0.0 2.3 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.6 ORY50853.1 - 0.14 12.6 2.6 14 6.1 0.0 2.9 2 1 0 3 3 2 0 AAA domain PhoH PF02562.16 ORY50853.1 - 0.14 11.6 0.0 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein cobW PF02492.19 ORY50853.1 - 0.16 11.6 0.5 3 7.4 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Hpr_kinase_C PF07475.12 ORY50853.1 - 0.34 10.4 1.4 28 4.2 0.1 2.7 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain AAA_21 PF13304.6 ORY50853.1 - 0.34 10.7 2.3 14 5.4 0.1 2.6 3 0 0 3 3 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 ORY50853.1 - 1.6 8.8 7.4 1.6 8.7 1.3 3.0 3 1 1 4 4 3 0 Helicase HerA, central domain DUF2087 PF09860.9 ORY50854.1 - 0.058 13.5 0.3 0.13 12.5 0.3 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) Gtr1_RagA PF04670.12 ORY50856.1 - 2.8e-55 187.2 7.0 8.2e-31 107.1 0.2 3.1 1 1 2 3 3 3 3 Gtr1/RagA G protein conserved region Sigma54_activat PF00158.26 ORY50856.1 - 0.028 14.1 0.0 0.083 12.6 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 ORY50856.1 - 0.052 14.1 0.1 0.079 13.5 0.1 1.6 1 1 0 1 1 1 0 ABC transporter RuvB_N PF05496.12 ORY50856.1 - 0.096 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 ORY50856.1 - 0.1 12.4 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Saf_2TM PF18303.1 ORY50858.1 - 0.34 10.5 4.0 0.24 11.0 0.5 2.3 1 1 1 2 2 2 0 SAVED-fused 2TM effector domain CcmH PF03918.14 ORY50858.1 - 0.95 8.7 5.5 4 6.7 0.0 2.6 3 0 0 3 3 3 0 Cytochrome C biogenesis protein PH PF00169.29 ORY50860.1 - 1.4e-07 32.0 0.1 3.2e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 PH domain SNF5 PF04855.12 ORY50861.1 - 1.1e-52 179.2 0.2 2.4e-28 99.6 0.0 2.2 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 GATA PF00320.27 ORY50861.1 - 6.1e-08 32.1 2.6 1e-07 31.4 2.6 1.4 1 0 0 1 1 1 1 GATA zinc finger NCA2 PF08637.10 ORY50862.1 - 3.5e-70 236.4 0.3 4e-38 131.2 0.1 2.4 2 0 0 2 2 2 2 ATP synthase regulation protein NCA2 PIH1 PF08190.12 ORY50863.1 - 7.7e-30 103.5 0.5 1.2e-25 89.9 0.0 2.7 3 0 0 3 3 3 2 PIH1 N-terminal domain PIH1_CS PF18201.1 ORY50863.1 - 2.2e-16 60.1 0.0 6.7e-16 58.5 0.0 1.9 2 0 0 2 2 2 1 PIH1 CS-like domain Lactamase_B_6 PF16661.5 ORY50864.1 - 3.8e-52 176.5 0.0 6.6e-52 175.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 ORY50864.1 - 2.6e-27 96.1 2.0 7.1e-27 94.7 0.2 2.4 2 1 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 ORY50864.1 - 7.7e-22 77.7 0.0 2.9e-21 75.8 0.0 2.0 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 ORY50864.1 - 1e-12 47.8 0.0 3e-12 46.3 0.0 1.9 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 ORY50864.1 - 6.7e-06 25.8 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY50864.1 - 8.3e-06 25.9 0.1 1.7e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily pXO2-34 PF17362.2 ORY50864.1 - 0.14 12.0 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function DNA_ligase_A_M PF01068.21 ORY50865.1 - 4.1e-31 108.2 0.0 6.7e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 ORY50865.1 - 1.8e-11 44.7 0.1 3.5e-11 43.7 0.1 1.4 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 ORY50865.1 - 2.3e-07 31.3 0.0 4.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 ORY50865.1 - 0.008 16.0 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain Cyclin PF08613.11 ORY50866.1 - 9.8e-37 126.8 0.2 1.4e-36 126.3 0.2 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 ORY50866.1 - 9.5e-07 28.6 0.1 1.4e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain NPR2 PF06218.11 ORY50867.1 - 1.1e-103 347.3 4.4 5.6e-82 275.8 3.8 3.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.13 ORY50867.1 - 0.00011 21.2 0.4 0.28 9.9 0.1 2.8 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 cNMP_binding PF00027.29 ORY50869.1 - 7.6e-52 173.3 0.8 2.9e-16 59.3 0.1 3.3 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain mTERF PF02536.14 ORY50869.1 - 0.071 12.0 3.3 0.1 11.5 0.1 2.6 3 0 0 3 3 3 0 mTERF Peptidase_S49_N PF08496.10 ORY50869.1 - 0.29 11.2 2.6 5 7.2 0.5 2.5 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Com_YlbF PF06133.11 ORY50869.1 - 0.52 10.9 15.8 0.13 12.9 0.8 3.9 3 1 1 4 4 4 0 Control of competence regulator ComK, YlbF/YmcA SlyX PF04102.12 ORY50869.1 - 9 7.0 7.0 2.1 9.0 1.9 2.4 2 0 0 2 2 2 0 SlyX Rib_recp_KP_reg PF05104.12 ORY50872.1 - 0.63 11.1 3.8 0.91 10.6 3.8 1.2 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region Pribosyltran PF00156.27 ORY50874.1 - 2.7e-14 53.0 0.2 2.8e-13 49.7 0.1 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain PA PF02225.22 ORY50874.1 - 0.0026 17.7 0.2 0.0041 17.1 0.2 1.3 1 0 0 1 1 1 1 PA domain CPT PF07931.12 ORY50874.1 - 0.015 15.2 0.1 0.02 14.7 0.1 1.2 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TFIIS_C PF01096.18 ORY50875.1 - 4.5e-20 71.2 3.8 4.5e-20 71.2 3.8 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 ORY50875.1 - 3.7e-09 36.3 1.9 3.7e-09 36.3 1.9 2.9 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 ORY50875.1 - 0.00074 19.4 5.3 0.0078 16.2 0.4 2.6 2 1 0 2 2 2 1 Transposase zinc-ribbon domain DUF2752 PF10825.8 ORY50875.1 - 0.029 14.4 5.5 0.86 9.7 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2752) TF_Zn_Ribbon PF08271.12 ORY50875.1 - 0.032 13.7 11.0 0.44 10.1 2.4 2.8 2 2 0 2 2 2 0 TFIIB zinc-binding SAG PF04092.13 ORY50875.1 - 0.037 14.8 0.2 0.038 14.8 0.2 1.1 1 0 0 1 1 1 0 SRS domain DZR PF12773.7 ORY50875.1 - 0.068 13.2 10.0 1.4 9.0 1.1 2.7 2 2 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.6 ORY50875.1 - 0.15 11.5 0.0 0.15 11.5 0.0 3.4 4 0 0 4 4 4 0 zinc-ribbon domain DpnI PF06044.12 ORY50875.1 - 0.42 10.2 5.4 2.9 7.5 0.5 2.1 1 1 1 2 2 2 0 Dam-replacing family HscB_4_cys PF18256.1 ORY50875.1 - 0.57 10.0 4.5 15 5.5 0.2 3.2 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif DUF2387 PF09526.10 ORY50875.1 - 0.81 9.9 6.4 1.1 9.4 1.1 2.4 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) zinc_ribbon_2 PF13240.6 ORY50875.1 - 1 9.2 10.4 3.2 7.6 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain CpXC PF14353.6 ORY50875.1 - 3.6 7.6 7.5 3.5 7.7 2.0 2.8 1 1 1 2 2 2 0 CpXC protein SLAIN PF15301.6 ORY50876.1 - 0.0037 16.6 3.2 0.0053 16.1 3.2 1.3 1 0 0 1 1 1 1 SLAIN motif-containing family TFIIF_alpha PF05793.12 ORY50876.1 - 0.57 8.7 3.1 0.7 8.4 3.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FYRN PF05964.14 ORY50877.1 - 2e-19 69.1 0.1 3.4e-19 68.4 0.1 1.3 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.14 ORY50877.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 F/Y rich C-terminus DUF2046 PF09755.9 ORY50877.1 - 0.093 11.9 0.1 0.11 11.6 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) EF1_GNE PF00736.19 ORY50878.1 - 2.9e-34 117.1 1.5 2.9e-34 117.1 1.5 1.8 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 ORY50878.1 - 4.7e-12 46.1 6.0 4.7e-12 46.1 6.0 1.9 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 ORY50878.1 - 0.00097 19.3 0.1 0.0033 17.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY50878.1 - 0.017 15.3 1.0 0.056 13.7 0.1 2.3 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain ATP-synt_E PF05680.12 ORY50878.1 - 0.13 12.6 0.8 0.26 11.6 0.8 1.6 1 0 0 1 1 1 0 ATP synthase E chain Mpv17_PMP22 PF04117.12 ORY50879.1 - 1.4e-20 73.2 1.2 1.4e-20 73.2 1.2 2.2 3 0 0 3 3 3 1 Mpv17 / PMP22 family Dynactin_p62 PF05502.13 ORY50880.1 - 2.2e-28 99.3 0.8 3.2e-28 98.8 0.8 1.2 1 0 0 1 1 1 1 Dynactin p62 family Dynactin_p62 PF05502.13 ORY50881.1 - 8.5e-29 100.7 15.4 1.5e-28 99.8 15.4 1.4 1 1 0 1 1 1 1 Dynactin p62 family MMM1 PF10296.9 ORY50882.1 - 1.2e-59 202.0 0.0 2.6e-57 194.4 0.0 2.0 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 SH3_9 PF14604.6 ORY50883.1 - 1.7e-07 31.0 0.0 3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY50883.1 - 0.00032 20.2 1.2 0.00039 20.0 0.0 1.7 2 0 0 2 2 2 1 SH3 domain Mucin PF01456.17 ORY50883.1 - 0.012 15.6 18.6 0.012 15.6 18.6 3.6 2 2 1 3 3 3 0 Mucin-like glycoprotein Tetraspanin PF00335.20 ORY50883.1 - 0.026 14.2 0.6 0.11 12.2 1.5 1.6 2 0 0 2 2 2 0 Tetraspanin family CD34_antigen PF06365.12 ORY50883.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family MIP PF00230.20 ORY50884.1 - 1.7e-49 168.6 16.9 2.1e-49 168.3 16.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein MIP PF00230.20 ORY50885.1 - 1.4e-48 165.5 16.2 1.7e-48 165.3 16.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein MPC PF03650.13 ORY50885.1 - 0.28 11.3 2.1 15 5.8 0.4 2.4 2 0 0 2 2 2 0 Mitochondrial pyruvate carriers MIP PF00230.20 ORY50886.1 - 1.8e-45 155.4 20.4 2.4e-45 155.0 20.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF1440 PF07274.12 ORY50886.1 - 0.6 10.5 4.7 0.47 10.8 2.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1440) MIP PF00230.20 ORY50887.1 - 3e-40 138.4 16.0 3.6e-40 138.1 16.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein PRA1 PF03208.19 ORY50887.1 - 1.7 8.3 6.6 4.9 6.8 6.6 1.8 1 1 0 1 1 1 0 PRA1 family protein MIP PF00230.20 ORY50888.1 - 2.3e-47 161.6 19.2 2.6e-47 161.4 19.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein MPC PF03650.13 ORY50888.1 - 0.041 14.0 1.0 7.3 6.8 0.2 2.5 2 0 0 2 2 2 0 Mitochondrial pyruvate carriers CX9C PF16860.5 ORY50889.1 - 1.2e-16 60.5 10.1 1.2e-10 41.2 1.9 2.1 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 ORY50889.1 - 2.4e-05 24.3 6.3 0.00036 20.5 0.5 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 ORY50889.1 - 0.00018 21.6 1.8 0.078 13.1 0.0 3.0 1 1 2 3 3 3 3 CHCH domain Pet191_N PF10203.9 ORY50889.1 - 0.0025 18.1 8.8 0.23 11.8 1.9 2.4 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 GCK PF07802.11 ORY50889.1 - 0.035 14.5 6.2 0.12 12.8 0.7 2.4 1 1 1 2 2 2 0 GCK domain UPF0203 PF05254.12 ORY50889.1 - 0.26 11.6 8.3 6.2 7.1 1.5 3.4 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0203) MTCP1 PF08991.10 ORY50889.1 - 3.9 7.8 10.3 0.68 10.2 1.4 2.5 1 1 0 2 2 2 0 Mature-T-Cell Proliferation I type MIP PF00230.20 ORY50890.1 - 1.1e-47 162.6 20.3 1.3e-47 162.4 20.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein MPC PF03650.13 ORY50890.1 - 0.1 12.8 3.0 7.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial pyruvate carriers DUF2070 PF09843.9 ORY50890.1 - 1.4 7.1 13.0 1.7 6.8 13.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Glyco_hydro_26 PF02156.15 ORY50891.1 - 1.5e-11 44.3 2.1 2.1e-11 43.8 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Dus PF01207.17 ORY50892.1 - 1.2e-59 202.0 0.0 1.4e-59 201.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) TMP-TENI PF02581.17 ORY50892.1 - 9.7e-05 21.8 0.1 0.00015 21.1 0.1 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase Oxidored_FMN PF00724.20 ORY50892.1 - 0.001 18.4 0.1 0.0023 17.3 0.1 1.4 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.21 ORY50892.1 - 0.067 12.6 0.1 0.13 11.7 0.0 1.5 2 0 0 2 2 2 0 Histidine biosynthesis protein SopD PF11047.8 ORY50892.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Salmonella outer protein D Pkinase PF00069.25 ORY50893.1 - 4.6e-51 173.7 0.0 5.9e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY50893.1 - 4.1e-29 101.6 0.0 5.2e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY50893.1 - 0.024 13.9 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 ORY50893.1 - 0.042 13.8 0.0 2.6 7.9 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 ORY50893.1 - 0.062 12.9 1.7 4.8 6.8 0.0 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ion_trans PF00520.31 ORY50894.1 - 7.4e-16 58.1 10.1 7.4e-16 58.1 10.1 1.6 2 0 0 2 2 2 1 Ion transport protein cNMP_binding PF00027.29 ORY50894.1 - 1.4e-05 25.1 0.0 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF3429 PF11911.8 ORY50895.1 - 0.0044 17.3 3.3 0.0061 16.8 3.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3429) TauE PF01925.19 ORY50895.1 - 0.026 14.2 12.3 0.033 13.8 12.3 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE PIG-P PF08510.12 ORY50895.1 - 0.064 13.2 2.5 0.1 12.5 2.5 1.3 1 0 0 1 1 1 0 PIG-P ThrE PF06738.12 ORY50895.1 - 1.6 8.1 6.8 1.1 8.5 5.7 1.4 1 1 0 1 1 1 0 Putative threonine/serine exporter DUF3270 PF11674.8 ORY50895.1 - 4.9 7.4 8.8 0.96 9.7 1.3 2.5 2 2 1 3 3 3 0 Protein of unknown function (DUF3270) AgrB PF04647.15 ORY50895.1 - 5.5 6.2 9.7 19 4.5 6.1 1.9 1 1 1 2 2 2 0 Accessory gene regulator B ECH_2 PF16113.5 ORY50896.1 - 1.7e-121 405.8 0.0 2.2e-121 405.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 ORY50896.1 - 1.4e-36 126.1 0.5 2.8e-32 112.0 0.0 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase DHHA2 PF02833.14 ORY50897.1 - 1e-21 77.6 0.7 1.6e-21 77.0 0.7 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 ORY50897.1 - 2.1e-10 40.8 0.0 4.1e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 DHH family FHA PF00498.26 ORY50898.1 - 8.7e-14 51.6 0.0 1.5e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 ORY50898.1 - 4.3e-10 39.2 12.1 8.6e-10 38.2 12.1 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 ORY50898.1 - 1.9e-07 31.3 12.4 3.3e-07 30.5 12.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 ORY50898.1 - 4.1e-05 23.5 3.0 9.1e-05 22.4 3.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 ORY50898.1 - 0.00032 20.6 8.7 0.00065 19.6 8.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 ORY50898.1 - 0.0058 16.9 10.0 0.015 15.6 10.0 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORY50898.1 - 0.0076 16.1 13.5 0.014 15.2 13.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 ORY50898.1 - 0.0076 16.5 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_3 PF13920.6 ORY50898.1 - 0.0095 15.8 10.8 0.018 14.9 10.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY50898.1 - 0.01 15.7 13.7 0.018 14.9 13.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 ORY50898.1 - 0.33 10.9 9.3 0.62 10.0 9.3 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 ORY50898.1 - 0.8 9.8 11.3 1.7 8.7 11.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger AT_hook PF02178.19 ORY50900.1 - 0.012 15.3 0.8 0.037 13.9 0.8 1.9 1 0 0 1 1 1 0 AT hook motif TPR_22 PF18833.1 ORY50900.1 - 0.051 13.7 0.1 0.088 13.0 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat HTH_28 PF13518.6 ORY50900.1 - 0.48 10.6 0.0 0.48 10.6 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain eIF3_N PF09440.10 ORY50901.1 - 4.6e-28 98.3 6.3 2.5e-21 76.5 1.6 3.0 2 1 1 3 3 3 2 eIF3 subunit 6 N terminal domain PCI PF01399.27 ORY50901.1 - 6e-13 49.2 0.0 1.9e-12 47.6 0.0 1.9 1 0 0 1 1 1 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 ORY50901.1 - 0.0002 21.4 0.1 0.0011 18.9 0.0 2.1 1 1 1 2 2 2 1 CSN8/PSMD8/EIF3K family TPR_3 PF07720.12 ORY50901.1 - 0.07 13.2 0.3 0.16 12.0 0.3 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY50901.1 - 0.08 13.2 0.2 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Cyclin_N PF00134.23 ORY50902.1 - 1.3e-10 41.1 0.0 1.9e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORY50902.1 - 5.3e-07 30.1 0.0 8.8e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin PALP PF00291.25 ORY50904.1 - 5.7e-70 236.1 0.2 2.8e-67 227.2 0.1 2.5 2 1 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 ORY50904.1 - 3.4e-44 148.5 0.0 7e-26 89.8 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase ADH_zinc_N PF00107.26 ORY50904.1 - 0.024 14.6 0.4 1.2 9.1 0.1 2.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase MFS_1 PF07690.16 ORY50905.1 - 1e-09 37.8 32.0 1.8e-09 37.0 20.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Spc7 PF08317.11 ORY50906.1 - 0.0018 17.2 84.8 0.014 14.3 21.5 5.1 1 1 4 5 5 5 4 Spc7 kinetochore protein Filament PF00038.21 ORY50906.1 - 0.005 16.5 30.1 0.005 16.5 30.1 4.9 1 1 2 3 3 3 1 Intermediate filament protein DUF1664 PF07889.12 ORY50906.1 - 0.016 15.2 48.4 0.7 9.9 6.2 6.7 3 3 3 6 6 6 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 ORY50906.1 - 0.25 11.6 27.2 2.6 8.3 2.9 5.4 3 3 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF4094 PF13334.6 ORY50906.1 - 0.34 11.3 0.1 0.34 11.3 0.1 5.4 3 3 3 6 6 6 0 Domain of unknown function (DUF4094) Uso1_p115_C PF04871.13 ORY50906.1 - 3.1 8.2 75.2 0.19 12.1 4.3 6.1 2 1 2 5 5 5 0 Uso1 / p115 like vesicle tethering protein, C terminal region CENP-F_leu_zip PF10473.9 ORY50906.1 - 9.5 6.2 96.9 0.07 13.2 7.6 5.6 1 1 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MAD PF05557.13 ORY50906.1 - 9.9 4.4 78.0 0.056 11.8 30.5 3.2 1 1 2 3 3 3 0 Mitotic checkpoint protein DUF4407 PF14362.6 ORY50907.1 - 8.9e-08 31.8 50.1 9.9e-05 21.8 10.8 3.4 2 1 1 3 3 3 2 Domain of unknown function (DUF4407) MscS_porin PF12795.7 ORY50907.1 - 0.0012 18.4 32.7 0.0049 16.5 13.8 4.5 1 1 3 4 4 4 2 Mechanosensitive ion channel porin domain MAD PF05557.13 ORY50907.1 - 0.0015 17.1 62.0 0.038 12.4 15.3 3.8 2 1 1 3 3 3 3 Mitotic checkpoint protein HOOK PF05622.12 ORY50907.1 - 0.003 15.8 18.7 0.003 15.8 18.7 3.5 2 2 1 3 3 3 1 HOOK protein FH2 PF02181.23 ORY50907.1 - 0.0054 15.9 8.1 0.0054 15.9 8.1 4.5 2 2 3 5 5 5 3 Formin Homology 2 Domain DUF4164 PF13747.6 ORY50907.1 - 0.0098 16.1 10.5 0.0098 16.1 10.5 6.6 3 3 1 5 5 5 1 Domain of unknown function (DUF4164) V-SNARE PF05008.15 ORY50907.1 - 0.018 15.4 51.2 0.025 14.9 12.3 6.0 4 2 1 5 5 5 0 Vesicle transport v-SNARE protein N-terminus DUF1759 PF03564.15 ORY50907.1 - 0.03 14.3 1.2 0.03 14.3 1.2 4.6 4 1 2 6 6 6 0 Protein of unknown function (DUF1759) Spc7 PF08317.11 ORY50907.1 - 0.052 12.4 76.7 0.012 14.5 14.5 4.3 2 2 1 3 3 3 0 Spc7 kinetochore protein Fez1 PF06818.15 ORY50907.1 - 0.098 13.1 63.4 1 9.8 18.4 3.6 1 1 1 3 3 3 0 Fez1 Lebercilin PF15619.6 ORY50907.1 - 0.16 11.6 70.4 0.56 9.8 25.0 4.1 1 1 3 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 ORY50907.1 - 0.4 10.0 77.6 0.026 13.9 13.6 5.0 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 ORY50907.1 - 0.92 9.7 85.8 0.076 13.2 11.6 5.7 2 1 3 5 5 4 0 Autophagy protein 16 (ATG16) DUF5082 PF16888.5 ORY50907.1 - 1.9 8.8 44.8 0.032 14.5 8.8 6.6 2 2 3 6 6 6 0 Domain of unknown function (DUF5082) Uso1_p115_C PF04871.13 ORY50907.1 - 4.7 7.6 79.8 0.12 12.7 9.5 5.8 1 1 3 5 5 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region PRKG1_interact PF15898.5 ORY50907.1 - 5.2 8.0 62.2 0.63 11.0 7.3 6.2 2 1 4 6 6 6 0 cGMP-dependent protein kinase interacting domain Macoilin PF09726.9 ORY50907.1 - 7.3 5.0 54.1 0.23 10.0 29.4 3.2 2 1 0 2 2 2 0 Macoilin family HMMR_N PF15905.5 ORY50907.1 - 8.3 5.8 75.5 2.2 7.7 23.3 3.6 2 2 1 3 3 3 0 Hyaluronan mediated motility receptor N-terminal R3H PF01424.22 ORY50908.1 - 0.0065 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 ORY50909.1 - 2.6e-08 33.7 49.6 3.4e-05 23.8 13.8 8.3 9 1 0 9 9 9 5 NF-X1 type zinc finger SH3_9 PF14604.6 ORY50910.1 - 1.5e-06 27.9 0.0 2.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY50910.1 - 0.00019 21.0 0.0 0.00029 20.4 0.0 1.3 1 0 0 1 1 1 1 SH3 domain DUF4078 PF13300.6 ORY50913.1 - 1.7e-13 50.6 7.9 1.7e-13 50.6 7.9 3.7 3 1 1 4 4 4 1 Domain of unknown function (DUF4078) VGCC_beta4Aa_N PF12052.8 ORY50913.1 - 0.1 12.7 0.0 0.1 12.7 0.0 3.7 4 0 0 4 4 4 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Nuc_sug_transp PF04142.15 ORY50914.1 - 1.8e-06 27.3 0.2 2.5e-06 26.9 0.2 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter PUNUT PF16913.5 ORY50914.1 - 0.0012 18.2 2.9 0.0013 18.1 2.9 1.2 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport 7TMR-DISM_7TM PF07695.11 ORY50914.1 - 0.11 12.4 8.8 0.1 12.4 4.4 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling DUF4231 PF14015.6 ORY50914.1 - 0.29 11.6 3.4 8.1 7.0 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) EamA PF00892.20 ORY50914.1 - 0.58 10.3 17.1 7.9 6.7 15.1 2.8 2 1 0 2 2 2 0 EamA-like transporter family DUF2157 PF09925.9 ORY50914.1 - 0.65 9.8 7.0 0.45 10.3 1.7 2.4 1 1 0 2 2 2 0 Predicted membrane protein (DUF2157) PTH2 PF01981.16 ORY50915.1 - 1.7e-33 115.4 0.0 2.5e-33 114.8 0.0 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 UBA PF00627.31 ORY50915.1 - 0.00037 20.3 0.0 0.00081 19.2 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain RuvA_C PF07499.13 ORY50915.1 - 0.042 14.3 0.1 0.11 13.0 0.1 1.7 1 0 0 1 1 1 0 RuvA, C-terminal domain Peptidase_M19 PF01244.21 ORY50916.1 - 1.5e-101 339.8 0.0 1.7e-101 339.6 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) ABC_tran PF00005.27 ORY50917.1 - 4.7e-31 108.1 0.3 7.4e-31 107.5 0.3 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 ORY50917.1 - 1.1e-09 38.4 0.0 1.7e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 ORY50917.1 - 1.9e-08 34.0 0.3 0.00022 20.7 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY50917.1 - 0.0011 18.7 0.1 0.0023 17.7 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.17 ORY50917.1 - 0.0033 17.6 0.1 0.0063 16.6 0.1 1.4 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_16 PF13191.6 ORY50917.1 - 0.0052 17.2 0.1 0.01 16.2 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 ORY50917.1 - 0.013 15.3 0.2 1.6 8.4 0.0 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 ORY50917.1 - 0.019 14.7 0.8 0.13 12.0 0.8 2.5 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ORY50917.1 - 0.021 14.9 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.9 ORY50917.1 - 0.096 11.6 0.1 0.19 10.6 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_7 PF12775.7 ORY50917.1 - 0.098 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Gtr1_RagA PF04670.12 ORY50917.1 - 0.14 11.5 0.7 0.27 10.6 0.1 1.8 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DEAD PF00270.29 ORY50917.1 - 0.14 11.9 1.8 0.73 9.6 1.8 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase Wound_ind PF08186.11 ORY50918.1 - 0.055 13.9 0.3 0.14 12.6 0.3 1.8 1 0 0 1 1 1 0 Wound-inducible basic protein family NBD94 PF16830.5 ORY50918.1 - 0.062 13.7 1.2 0.15 12.5 1.2 1.6 1 0 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH Cluap1 PF10234.9 ORY50918.1 - 0.08 12.3 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 KxDL PF10241.9 ORY50918.1 - 0.27 11.5 0.3 0.27 11.5 0.3 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein ABC_membrane PF00664.23 ORY50919.1 - 4.5e-15 56.0 6.8 6.9e-15 55.4 6.8 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region zf-MYND PF01753.18 ORY50920.1 - 1.1e-07 31.8 17.6 2.8e-07 30.5 17.6 1.7 1 0 0 1 1 1 1 MYND finger NfI_DNAbd_pre-N PF10524.9 ORY50920.1 - 0.04 13.8 0.3 0.26 11.2 0.1 2.2 2 0 0 2 2 2 0 Nuclear factor I protein pre-N-terminus BTG PF07742.12 ORY50921.1 - 4.6e-12 45.8 0.0 8e-12 45.0 0.0 1.4 2 0 0 2 2 2 1 BTG family CCD48 PF15799.5 ORY50921.1 - 0.11 10.8 0.5 0.13 10.5 0.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 ATP-grasp PF02222.22 ORY50922.1 - 4e-07 29.8 0.0 1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.6 ORY50922.1 - 4.5e-06 26.3 0.1 9.4e-06 25.3 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 ORY50922.1 - 2e-05 24.3 0.1 4.9e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 ORY50922.1 - 5.8e-05 22.7 0.0 9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_ST PF14397.6 ORY50922.1 - 0.0046 16.2 0.1 0.0097 15.2 0.1 1.5 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp TFIID_20kDa PF03847.13 ORY50923.1 - 6.4e-19 68.2 0.7 1e-18 67.6 0.7 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A TFIID-18kDa PF02269.16 ORY50923.1 - 0.00035 20.5 0.1 0.00076 19.5 0.0 1.6 1 1 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.23 ORY50923.1 - 0.00042 20.5 0.0 0.00074 19.8 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 ORY50923.1 - 0.0034 17.4 0.0 0.0044 17.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Pro_isomerase PF00160.21 ORY50924.1 - 1.5e-47 161.8 0.7 2.2e-47 161.2 0.7 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 ORY50924.1 - 6e-17 61.2 0.0 1.2e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY50924.1 - 0.00032 20.3 0.0 0.00056 19.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 ORY50924.1 - 0.015 15.4 0.0 0.049 13.8 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif ABC_membrane PF00664.23 ORY50925.1 - 1.7e-54 185.3 28.5 3.4e-30 105.6 14.0 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY50925.1 - 6.9e-39 133.5 0.5 2e-18 67.2 0.1 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 ORY50925.1 - 2.4e-06 27.2 0.8 0.047 13.1 0.0 3.7 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain BCA_ABC_TP_C PF12399.8 ORY50925.1 - 0.0035 17.2 0.6 0.0075 16.2 0.6 1.6 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter AAA_21 PF13304.6 ORY50925.1 - 0.0063 16.4 0.7 5.1 6.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system DEAD PF00270.29 ORY50925.1 - 0.0074 16.1 0.3 1.8 8.3 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_22 PF13401.6 ORY50925.1 - 0.017 15.4 0.5 0.38 11.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 ORY50925.1 - 0.036 14.2 0.5 0.1 12.7 0.1 1.9 2 0 0 2 2 2 0 Helicase HerA, central domain SbcCD_C PF13558.6 ORY50925.1 - 0.042 14.1 0.0 9.4 6.6 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 ORY50925.1 - 0.064 13.7 0.1 0.17 12.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 ORY50925.1 - 0.11 11.6 1.0 0.14 11.2 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein RXT2_N PF08595.11 ORY50926.1 - 1.6e-12 47.8 0.2 2.1e-12 47.3 0.2 1.2 1 0 0 1 1 1 1 RXT2-like, N-terminal Gly_transf_sug PF04488.15 ORY50927.1 - 2.9e-09 37.4 0.1 1.3e-08 35.3 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 ORY50927.1 - 0.019 14.3 0.1 0.044 13.1 0.1 1.5 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Gly_transf_sug PF04488.15 ORY50928.1 - 2e-15 57.2 0.0 3.7e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 ORY50928.1 - 0.0046 16.3 0.1 0.47 9.7 0.0 2.1 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Phage_Gp23 PF10669.9 ORY50929.1 - 0.00054 20.3 2.6 0.00054 20.3 2.6 2.8 2 1 1 3 3 3 1 Protein gp23 (Bacteriophage A118) MAPEG PF01124.18 ORY50930.1 - 2.9e-20 72.5 0.8 5.1e-20 71.7 0.8 1.5 1 1 0 1 1 1 1 MAPEG family TPPK_C PF12555.8 ORY50930.1 - 0.05 13.7 2.3 0.16 12.0 2.3 1.8 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal PHD PF00628.29 ORY50932.1 - 0.0002 21.2 13.9 0.0002 21.2 13.9 2.6 2 0 0 2 2 2 1 PHD-finger zf-MYND PF01753.18 ORY50933.1 - 2.2e-10 40.4 10.4 2.2e-10 40.4 10.4 1.7 2 0 0 2 2 2 1 MYND finger ANAPC5 PF12862.7 ORY50934.1 - 3.6e-21 75.0 6.3 7.4e-20 70.8 6.5 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_MalT PF17874.1 ORY50934.1 - 0.00099 18.6 0.1 0.025 13.9 0.3 2.1 2 0 0 2 2 2 1 MalT-like TPR region TPR_19 PF14559.6 ORY50934.1 - 0.0033 17.9 0.2 0.025 15.1 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Drf_FH3 PF06367.16 ORY50934.1 - 0.011 15.4 0.2 0.02 14.5 0.2 1.4 1 0 0 1 1 1 0 Diaphanous FH3 Domain DUF4807 PF16065.5 ORY50934.1 - 0.079 12.6 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4807) TPR_21 PF09976.9 ORY50934.1 - 0.11 12.3 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain Methyltr_RsmB-F PF01189.17 ORY50935.1 - 4.5e-31 108.1 0.1 2.4e-29 102.4 0.1 2.3 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 ORY50935.1 - 0.073 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Lectin_N PF03954.14 ORY50937.1 - 0.027 14.2 0.4 0.048 13.4 0.4 1.4 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Histidinol_dh PF00815.20 ORY50937.1 - 0.028 13.4 7.9 0.041 12.9 7.9 1.2 1 0 0 1 1 1 0 Histidinol dehydrogenase FlxA PF14282.6 ORY50937.1 - 0.079 13.0 0.9 0.079 13.0 0.9 2.6 2 1 1 3 3 3 0 FlxA-like protein Uds1 PF15456.6 ORY50937.1 - 0.08 13.1 8.2 0.028 14.6 5.5 1.7 2 1 0 2 2 2 0 Up-regulated During Septation Rootletin PF15035.6 ORY50937.1 - 0.087 12.8 0.6 0.12 12.4 0.6 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF4407 PF14362.6 ORY50937.1 - 0.11 11.8 11.8 0.16 11.3 11.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3138 PF11336.8 ORY50937.1 - 0.21 10.2 11.7 0.32 9.6 11.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DUF4366 PF14283.6 ORY50937.1 - 2.8 8.0 8.3 0.16 12.0 1.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) RR_TM4-6 PF06459.12 ORY50937.1 - 5.2 6.8 8.3 9.2 6.0 8.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SlyX PF04102.12 ORY50937.1 - 5.4 7.7 6.4 0.49 11.0 1.0 2.0 2 0 0 2 2 2 0 SlyX AMP-binding PF00501.28 ORY50938.1 - 1.3e-80 271.1 0.0 3e-80 269.9 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY50938.1 - 2.6e-24 86.0 0.0 1.1e-23 83.9 0.1 2.1 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 ORY50938.1 - 1.6e-16 60.0 0.5 5.7e-16 58.2 0.1 2.1 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AAA_24 PF13479.6 ORY50939.1 - 0.039 13.7 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Glyco_trans_2_3 PF13632.6 ORY50940.1 - 2.4e-26 92.9 4.7 2.4e-26 92.9 4.7 1.6 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY50940.1 - 2.3e-16 60.4 0.2 3.3e-16 59.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Rit1_C PF17184.4 ORY50941.1 - 1.2e-93 313.5 0.1 1.7e-93 313.0 0.1 1.1 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 ORY50941.1 - 1.1e-18 67.5 0.0 2.8e-18 66.2 0.0 1.7 2 0 0 2 2 2 1 Rit1 DUSP-like domain DSPc PF00782.20 ORY50941.1 - 6e-06 26.1 0.0 2e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY50941.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Metallophos PF00149.28 ORY50942.1 - 2.4e-16 60.9 0.1 3.5e-16 60.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 ORY50942.1 - 0.00021 19.7 0.0 0.0024 16.2 0.0 2.3 3 0 0 3 3 3 1 Firmicute fructose-1,6-bisphosphatase WW PF00397.26 ORY50943.1 - 0.00014 21.9 7.6 0.021 14.9 0.2 3.0 3 0 0 3 3 3 2 WW domain RNA_pol_Rpb2_3 PF04565.16 ORY50943.1 - 0.03 14.5 0.4 0.13 12.4 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 3 RVT_3 PF13456.6 ORY50945.1 - 9.1e-12 44.9 0.0 2.6e-11 43.4 0.0 1.9 1 1 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.24 ORY50945.1 - 5.1e-05 23.5 0.0 0.00012 22.3 0.0 1.6 1 1 0 1 1 1 1 RNase H Prim_Zn_Ribbon PF08273.12 ORY50946.1 - 0.065 13.5 7.8 1.1 9.6 6.2 2.2 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase TF_Zn_Ribbon PF08271.12 ORY50946.1 - 1.6 8.3 9.1 6.9 6.3 0.0 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding LRR_4 PF12799.7 ORY50947.1 - 1.1e-07 32.1 0.1 0.0066 16.8 0.0 3.7 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY50947.1 - 8.7e-06 25.4 1.0 0.048 13.4 0.2 2.7 1 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 ORY50947.1 - 0.013 15.9 5.1 42 5.3 0.1 5.9 5 1 1 6 6 6 0 Leucine Rich Repeat LMWPc PF01451.21 ORY50948.1 - 2e-20 73.6 0.0 2.5e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase NUDE_C PF04880.13 ORY50949.1 - 0.24 11.8 9.3 0.22 12.0 7.7 1.6 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region Methyltransf_21 PF05050.12 ORY50950.1 - 2.8e-14 53.5 0.0 3.8e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain BMF PF15185.6 ORY50950.1 - 0.00048 19.9 0.0 0.00068 19.4 0.0 1.2 1 0 0 1 1 1 1 Bcl-2-modifying factor, apoptosis Importin_rep_4 PF18808.1 ORY50953.1 - 6e-36 122.6 0.1 6e-36 122.6 0.1 4.1 5 0 0 5 5 4 1 Importin repeat HEAT_2 PF13646.6 ORY50953.1 - 2.7e-21 75.7 1.4 4.5e-06 27.0 0.0 7.2 4 2 3 7 7 7 5 HEAT repeats HEAT PF02985.22 ORY50953.1 - 1.4e-13 49.8 18.6 5.1e-05 23.2 0.0 11.3 13 0 0 13 13 13 2 HEAT repeat HEAT_EZ PF13513.6 ORY50953.1 - 3.6e-12 46.5 17.3 0.00032 21.1 0.0 9.8 10 4 3 13 13 13 3 HEAT-like repeat Importin_rep_6 PF18829.1 ORY50953.1 - 3.5e-10 40.0 0.1 3.5e-10 40.0 0.1 3.1 4 0 0 4 4 3 1 Importin repeat 6 Arm PF00514.23 ORY50953.1 - 8e-09 35.2 2.5 5.4 7.2 0.0 7.3 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat Cnd3 PF12719.7 ORY50953.1 - 1.3e-08 34.4 0.2 0.004 16.4 0.1 4.6 4 0 0 4 4 4 2 Nuclear condensing complex subunits, C-term domain DUF3385 PF11865.8 ORY50953.1 - 2.8e-08 33.8 7.4 4.1 7.3 0.0 7.7 5 2 2 7 7 7 2 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 ORY50953.1 - 7.4e-07 29.7 2.4 0.014 16.0 0.0 6.2 4 2 4 8 8 8 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 ORY50953.1 - 1e-06 28.9 0.1 0.0014 18.7 0.1 4.1 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 ORY50953.1 - 1.8e-05 24.6 0.1 2 8.1 0.0 5.1 4 1 2 6 6 6 2 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 ORY50953.1 - 0.00013 21.6 1.9 1.5 8.3 0.0 4.8 4 1 0 5 5 5 2 CLASP N terminal IBN_N PF03810.19 ORY50953.1 - 0.018 15.0 2.8 0.43 10.5 0.2 3.9 3 0 0 3 3 3 0 Importin-beta N-terminal domain Proteasom_PSMB PF10508.9 ORY50953.1 - 0.083 11.4 0.3 4.5 5.7 0.0 2.9 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit Pex24p PF06398.11 ORY50954.1 - 9.8e-14 51.1 4.2 1.1e-13 50.9 4.2 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Pex24p PF06398.11 ORY50955.1 - 2.1e-06 27.0 4.9 3.6e-06 26.2 4.9 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PRT_C PF08372.10 ORY50955.1 - 0.002 17.9 2.2 0.57 9.9 0.4 2.2 2 0 0 2 2 2 2 Plant phosphoribosyltransferase C-terminal DUF554 PF04474.12 ORY50955.1 - 0.0042 16.6 0.0 0.0074 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF554) Reticulon PF02453.17 ORY50955.1 - 0.3 11.0 10.3 68 3.4 10.3 3.0 1 1 0 1 1 1 0 Reticulon Gly_transf_sug PF04488.15 ORY50956.1 - 7.1e-14 52.2 0.5 1.9e-13 50.9 0.3 1.8 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 ORY50956.1 - 0.039 13.3 0.3 7.5 5.7 0.0 2.2 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain GTP_EFTU PF00009.27 ORY50957.1 - 4.1e-54 183.1 0.3 8e-54 182.1 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORY50957.1 - 1.1e-42 144.9 0.0 2e-42 144.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain NTP_transf_9 PF04248.12 ORY50957.1 - 1.2e-19 70.0 0.3 9.9e-19 67.0 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF427) GTP_EFTU_D2 PF03144.25 ORY50957.1 - 6.9e-15 55.2 4.3 7.2e-15 55.1 0.6 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY50957.1 - 0.00047 20.2 0.1 0.022 14.9 0.1 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 ORY50957.1 - 0.35 10.8 5.7 0.14 12.1 0.6 2.5 2 0 0 2 2 2 0 Elongation factor Tu domain 4 DUF3405 PF11885.8 ORY50958.1 - 1.8e-09 36.8 6.2 4.1e-09 35.6 3.4 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3405) INCENP_ARK-bind PF03941.15 ORY50959.1 - 0.12 12.3 0.4 0.12 12.3 0.4 1.8 2 0 0 2 2 2 0 Inner centromere protein, ARK binding region HARE-HTH PF05066.13 ORY50960.1 - 8.4e-06 26.1 0.0 1.8e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain Gly_transf_sug PF04488.15 ORY50961.1 - 5.8e-14 52.5 0.0 1e-13 51.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 ORY50961.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein MAPEG PF01124.18 ORY50962.1 - 3.7e-17 62.4 0.5 5.6e-17 61.9 0.5 1.3 1 0 0 1 1 1 1 MAPEG family Arm PF00514.23 ORY50963.1 - 1.7e-15 56.4 17.2 6.3e-05 22.9 0.0 8.3 8 0 0 8 8 8 5 Armadillo/beta-catenin-like repeat HEAT PF02985.22 ORY50963.1 - 7.9e-11 41.3 10.9 0.15 12.4 0.0 7.3 7 0 0 7 7 7 4 HEAT repeat Cnd1 PF12717.7 ORY50963.1 - 4.3e-05 23.6 7.1 0.008 16.2 0.0 4.8 4 2 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 ORY50963.1 - 0.00095 18.8 0.3 2 7.9 0.0 3.6 3 1 0 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.6 ORY50963.1 - 0.42 11.2 18.9 16 6.1 0.5 7.8 7 2 2 9 9 9 0 HEAT-like repeat AAA_16 PF13191.6 ORY50964.1 - 5.4e-16 59.4 0.1 2.7e-08 34.4 0.0 2.8 3 0 0 3 3 2 2 AAA ATPase domain TPR_2 PF07719.17 ORY50964.1 - 6.1e-05 22.8 0.3 0.22 11.7 0.1 3.5 2 0 0 2 2 2 2 Tetratricopeptide repeat AAA_22 PF13401.6 ORY50964.1 - 0.00075 19.8 0.1 0.046 14.0 0.1 2.9 2 0 0 2 2 2 1 AAA domain TPR_1 PF00515.28 ORY50964.1 - 0.0014 18.4 5.1 0.24 11.3 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY50964.1 - 0.0027 18.0 4.2 2.6 8.4 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat RsgA_GTPase PF03193.16 ORY50964.1 - 0.0039 17.1 0.2 0.011 15.7 0.2 1.7 1 0 0 1 1 1 1 RsgA GTPase NB-ARC PF00931.22 ORY50964.1 - 0.0042 16.3 0.4 0.028 13.6 0.3 2.1 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 ORY50964.1 - 0.0096 15.8 0.4 1.3 8.9 0.0 2.8 3 0 0 3 3 2 1 NACHT domain DnaB_C PF03796.15 ORY50964.1 - 0.02 14.2 0.2 0.069 12.5 0.1 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Sulfotransfer_4 PF17784.1 ORY50964.1 - 0.026 14.3 0.1 0.28 11.0 0.0 2.4 2 0 0 2 2 2 0 Sulfotransferase domain Guanylate_cyc PF00211.20 ORY50964.1 - 0.026 14.1 0.1 0.32 10.6 0.0 2.4 2 0 0 2 2 2 0 Adenylate and Guanylate cyclase catalytic domain DAP3 PF10236.9 ORY50964.1 - 0.038 13.1 1.0 0.16 11.1 0.1 2.4 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_7 PF12775.7 ORY50964.1 - 0.071 12.6 2.0 0.063 12.8 0.2 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_30 PF13604.6 ORY50964.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_8 PF13181.6 ORY50964.1 - 0.15 12.3 2.8 0.2 11.9 0.1 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat ABC_tran PF00005.27 ORY50964.1 - 0.33 11.5 6.0 2.2 8.8 6.0 2.5 1 1 0 1 1 1 0 ABC transporter DUF2457 PF10446.9 ORY50965.1 - 0.14 11.3 8.1 0.19 10.8 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Pkinase PF00069.25 ORY50966.1 - 1.4e-65 221.3 0.2 3.6e-65 220.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY50966.1 - 8.6e-33 113.7 0.0 2.2e-32 112.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase LMBR1 PF04791.16 ORY50966.1 - 0.015 14.3 6.8 0.026 13.5 6.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Ribosom_S12_S23 PF00164.25 ORY50967.1 - 0.041 13.5 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S12/S23 CENP-B_dimeris PF09026.10 ORY50967.1 - 0.13 12.7 6.2 0.27 11.7 6.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 ORY50967.1 - 0.22 10.8 3.9 0.32 10.3 3.9 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 ORY50967.1 - 2.8 8.4 12.7 0.26 11.7 6.9 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SNF2_N PF00176.23 ORY50968.1 - 2.2e-64 217.4 0.0 3.6e-64 216.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY50968.1 - 1.2e-20 73.9 0.0 2.5e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY50968.1 - 3.8e-08 33.5 0.0 1.3e-07 31.8 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 ORY50968.1 - 0.0001 21.6 0.0 0.00045 19.5 0.0 2.1 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Peptidase_M18 PF02127.15 ORY50969.1 - 2.6e-176 586.6 0.0 3e-176 586.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 ORY50969.1 - 7.4e-09 35.0 0.4 8.9e-06 24.9 0.1 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase tRNA_SAD PF07973.14 ORY50970.1 - 2.4e-08 33.9 0.1 5.4e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 ORY50970.1 - 1e-05 24.3 0.1 1.4e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) PRIMA1 PF16101.5 ORY50971.1 - 0.74 9.9 10.7 0.43 10.6 8.5 1.8 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Presenilin PF01080.17 ORY50973.1 - 0.49 9.1 8.5 0.5 9.1 8.5 1.1 1 0 0 1 1 1 0 Presenilin DUF455 PF04305.14 ORY50974.1 - 3 7.3 5.4 0.43 10.1 1.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF455) TPT PF03151.16 ORY50975.1 - 3.2e-22 79.2 9.4 3.9e-22 79.0 9.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 ORY50975.1 - 4.4e-10 39.9 29.9 7.1e-09 35.9 9.1 2.6 2 1 0 2 2 2 2 EamA-like transporter family Sporozoite_P67 PF05642.11 ORY50976.1 - 4.7 5.2 7.4 4.8 5.1 7.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HLH PF00010.26 ORY50977.1 - 3.3e-12 46.2 0.6 1.3e-11 44.2 0.5 2.1 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain NinF PF05810.12 ORY50977.1 - 0.087 12.7 0.2 2.1 8.3 0.1 2.5 2 0 0 2 2 2 0 NinF protein Rx_N PF18052.1 ORY50977.1 - 0.26 11.6 1.3 3.9 7.8 0.1 2.5 2 0 0 2 2 2 0 Rx N-terminal domain CCDC144C PF14915.6 ORY50977.1 - 0.5 9.4 4.6 3.2 6.8 4.6 1.9 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region MGC-24 PF05283.11 ORY50978.1 - 0.00059 20.3 2.9 0.0012 19.4 2.9 1.5 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin LRR_8 PF13855.6 ORY50978.1 - 0.0045 16.7 0.0 0.071 12.9 0.0 2.1 1 1 1 3 3 3 1 Leucine rich repeat Orthoreo_P10 PF07204.11 ORY50978.1 - 0.0075 16.2 0.4 0.016 15.1 0.4 1.5 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 TMEM154 PF15102.6 ORY50978.1 - 0.014 15.3 0.1 0.021 14.7 0.1 1.1 1 0 0 1 1 1 0 TMEM154 protein family Alpha_GJ PF03229.13 ORY50978.1 - 0.034 14.7 7.1 0.069 13.7 7.1 1.5 1 0 0 1 1 1 0 Alphavirus glycoprotein J DUF1180 PF06679.12 ORY50978.1 - 0.068 13.6 3.4 0.1 13.0 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) UPF0560 PF10577.9 ORY50978.1 - 0.17 10.4 0.0 0.22 10.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TMEM154 PF15102.6 ORY50979.1 - 0.00018 21.4 0.2 0.00028 20.8 0.2 1.2 1 0 0 1 1 1 1 TMEM154 protein family DAP10 PF07213.11 ORY50979.1 - 0.0068 16.3 0.1 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 DAP10 membrane protein Glycoprotein PF03409.15 ORY50979.1 - 0.014 14.3 1.5 0.021 13.7 1.5 1.2 1 0 0 1 1 1 0 Transmembrane glycoprotein RIFIN PF02009.16 ORY50979.1 - 0.014 15.3 0.0 0.018 15.0 0.0 1.1 1 0 0 1 1 1 0 Rifin Herpes_gE PF02480.16 ORY50979.1 - 0.015 14.1 0.0 0.019 13.7 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.6 ORY50979.1 - 0.021 15.7 0.0 0.038 14.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.11 ORY50979.1 - 0.027 14.4 0.1 0.047 13.7 0.1 1.3 1 0 0 1 1 1 0 Protocadherin Mid2 PF04478.12 ORY50979.1 - 0.042 13.7 1.2 0.07 13.0 1.2 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF3827 PF12877.7 ORY50979.1 - 0.071 11.5 0.1 0.094 11.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) TraL PF07178.11 ORY50979.1 - 0.08 13.4 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 TraL protein Syndecan PF01034.20 ORY50979.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain MGC-24 PF05283.11 ORY50979.1 - 0.8 10.2 7.5 1.3 9.4 7.5 1.4 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Orthoreo_P10 PF07204.11 ORY50979.1 - 1.1 9.3 5.5 0.22 11.5 2.0 1.7 2 1 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 Phage_Coat_B PF05356.11 ORY50979.1 - 4.3 7.3 6.3 1.4 8.9 3.3 1.8 2 0 0 2 2 2 0 Phage Coat protein B Adeno_E3_CR2 PF02439.15 ORY50979.1 - 6.3 6.7 6.6 0.51 10.1 1.8 1.6 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 LRR_8 PF13855.6 ORY50981.1 - 0.024 14.4 0.1 0.075 12.8 0.1 1.8 2 0 0 2 2 2 0 Leucine rich repeat LRR_1 PF00560.33 ORY50981.1 - 0.036 14.6 4.2 0.67 10.7 0.5 3.6 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.7 ORY50981.1 - 0.057 13.9 0.6 0.6 10.6 0.0 2.8 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) CNH PF00780.22 ORY50983.1 - 2.7e-16 60.0 0.0 1.4e-14 54.4 0.0 2.4 1 1 0 1 1 1 1 CNH domain Vps39_2 PF10367.9 ORY50983.1 - 3.7e-10 40.2 0.5 1.5e-07 31.8 0.5 2.9 1 1 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 ORY50983.1 - 0.0012 19.1 0.7 0.019 15.2 0.1 3.0 2 1 1 3 3 3 1 Vacuolar sorting protein 39 domain 1 DivIVA PF05103.13 ORY50984.1 - 0.69 10.0 10.8 0.1 12.7 5.8 2.2 2 0 0 2 2 2 0 DivIVA protein DUF2635 PF10948.8 ORY50985.1 - 0.093 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2635) Hormone_6 PF00236.18 ORY50985.1 - 0.18 11.8 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein hormone TauE PF01925.19 ORY50986.1 - 0.00054 19.7 0.3 0.00056 19.6 0.3 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE DUF1430 PF07242.11 ORY50986.1 - 0.00095 19.4 2.8 0.0012 19.1 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1430) DUF4131 PF13567.6 ORY50986.1 - 0.0016 18.1 0.7 0.0018 17.9 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF2207 PF09972.9 ORY50986.1 - 0.0016 17.3 0.5 0.0018 17.1 0.5 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF4191 PF13829.6 ORY50986.1 - 0.0028 17.0 0.5 0.0032 16.8 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) DUF4199 PF13858.6 ORY50986.1 - 0.0031 17.9 0.6 0.0038 17.6 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) Phage_holin_3_6 PF07332.11 ORY50986.1 - 0.0034 17.4 1.4 0.0044 17.1 1.4 1.1 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III Halogen_Hydrol PF10112.9 ORY50986.1 - 0.0035 17.4 1.0 0.0042 17.1 1.0 1.0 1 0 0 1 1 1 1 5-bromo-4-chloroindolyl phosphate hydrolysis protein MerC PF03203.14 ORY50986.1 - 0.012 16.0 1.3 0.012 16.0 1.3 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein SPC25 PF06703.11 ORY50986.1 - 0.013 15.3 1.0 0.015 15.1 1.0 1.1 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) LptF_LptG PF03739.14 ORY50986.1 - 0.014 14.3 0.3 0.015 14.2 0.3 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF202 PF02656.15 ORY50986.1 - 0.016 15.7 5.6 0.023 15.1 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) DUF2418 PF10332.9 ORY50986.1 - 0.019 15.5 0.3 0.022 15.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2418) YfhO PF09586.10 ORY50986.1 - 0.019 13.3 1.1 0.02 13.2 1.1 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO CcmF_C PF16327.5 ORY50986.1 - 0.021 14.1 2.3 0.023 14.0 2.3 1.0 1 0 0 1 1 1 0 Cytochrome c-type biogenesis protein CcmF C-terminal FA_hydroxylase PF04116.13 ORY50986.1 - 0.028 14.8 0.6 0.034 14.5 0.6 1.0 1 0 0 1 1 1 0 Fatty acid hydroxylase superfamily S_4TM PF18159.1 ORY50986.1 - 0.04 13.2 2.7 0.045 13.1 2.7 1.0 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain DUF1180 PF06679.12 ORY50986.1 - 0.04 14.3 0.3 0.06 13.8 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) FA_desaturase PF00487.24 ORY50986.1 - 0.048 13.5 3.6 0.048 13.5 3.6 1.1 1 0 0 1 1 1 0 Fatty acid desaturase DUF3169 PF11368.8 ORY50986.1 - 0.054 13.0 3.5 0.59 9.6 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) YlaC PF10777.9 ORY50986.1 - 0.054 13.3 2.1 0.067 13.0 2.1 1.1 1 0 0 1 1 1 0 Inner membrane protein YlaC DUF2614 PF11023.8 ORY50986.1 - 0.079 13.1 1.8 0.1 12.7 1.8 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain FtsL PF04999.13 ORY50986.1 - 0.085 12.9 8.7 0.15 12.1 0.4 2.1 1 1 1 2 2 2 0 Cell division protein FtsL DUF2070 PF09843.9 ORY50986.1 - 0.088 11.1 0.7 0.097 10.9 0.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) RseC_MucC PF04246.12 ORY50986.1 - 0.1 12.5 0.9 0.13 12.2 0.9 1.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Herpes_LMP1 PF05297.11 ORY50986.1 - 0.15 11.2 1.7 0.16 11.1 1.7 1.0 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF805 PF05656.14 ORY50986.1 - 0.16 12.4 1.9 0.19 12.1 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) SurA_N_3 PF13624.6 ORY50986.1 - 0.25 11.1 0.2 0.25 11.1 0.2 1.6 1 1 1 2 2 2 0 SurA N-terminal domain EphA2_TM PF14575.6 ORY50986.1 - 0.36 11.8 3.6 0.57 11.1 0.0 2.0 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Wzy_C PF04932.15 ORY50986.1 - 0.38 10.4 5.1 0.55 9.9 5.1 1.4 1 1 0 1 1 1 0 O-Antigen ligase EMC3_TMCO1 PF01956.16 ORY50986.1 - 0.43 10.3 4.6 13 5.5 4.6 2.1 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF4231 PF14015.6 ORY50986.1 - 0.46 11.0 8.0 0.65 10.5 8.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Tweety PF04906.13 ORY50986.1 - 0.83 8.3 6.4 0.99 8.0 6.4 1.1 1 0 0 1 1 1 0 Tweety DUF3742 PF12553.8 ORY50986.1 - 1.1 9.4 6.8 2.4 8.3 4.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3742) COX14 PF14880.6 ORY50986.1 - 1.6 8.6 6.5 13 5.7 6.5 2.0 1 1 0 1 1 1 0 Cytochrome oxidase c assembly LRR19-TM PF15176.6 ORY50986.1 - 2 8.5 5.0 15 5.7 5.0 2.0 1 1 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF2681 PF10883.8 ORY50986.1 - 2.4 8.6 6.2 0.54 10.7 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Lig_chan PF00060.26 ORY50986.1 - 3 7.7 5.4 0.31 10.8 0.3 1.8 1 1 1 2 2 2 0 Ligand-gated ion channel DUF4381 PF14316.6 ORY50986.1 - 4.1 7.6 9.7 0.23 11.7 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) DUF1129 PF06570.11 ORY50987.1 - 0.0033 17.0 0.5 0.0033 16.9 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1129) ATP-synt_I PF03899.15 ORY50987.1 - 0.0039 17.5 3.6 0.0049 17.2 3.6 1.1 1 0 0 1 1 1 1 ATP synthase I chain DUF4271 PF14093.6 ORY50987.1 - 0.0068 16.3 4.8 0.0079 16.1 4.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) BPD_transp_1 PF00528.22 ORY50987.1 - 0.011 15.5 3.4 0.013 15.2 3.4 1.1 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component DUF2207 PF09972.9 ORY50987.1 - 0.027 13.3 1.4 0.027 13.2 1.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4191 PF13829.6 ORY50987.1 - 0.048 13.0 1.7 0.053 12.9 1.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Orai-1 PF07856.12 ORY50987.1 - 0.055 13.1 4.1 0.062 13.0 4.1 1.1 1 0 0 1 1 1 0 Mediator of CRAC channel activity PCI PF01399.27 ORY50988.1 - 1.8e-08 34.8 0.0 4.5e-08 33.5 0.0 1.6 2 0 0 2 2 2 1 PCI domain Phytochelatin PF05023.14 ORY50990.1 - 2.5e-76 255.6 0.0 3.9e-76 255.0 0.0 1.2 1 0 0 1 1 1 1 Phytochelatin synthase Ion_trans PF00520.31 ORY50991.1 - 1.4e-20 73.6 26.5 8.9e-20 71.0 26.5 1.9 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 ORY50991.1 - 4e-07 29.9 12.1 4e-07 29.9 12.1 2.3 2 1 0 2 2 2 1 Ion channel DUF3274 PF11678.8 ORY50991.1 - 0.00018 20.9 0.4 0.00039 19.7 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3274) Glyco_hydro_26 PF02156.15 ORY50992.1 - 2.1e-07 30.7 1.6 3.2e-07 30.1 1.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 ABC2_membrane_2 PF12679.7 ORY50993.1 - 0.061 12.6 0.0 0.092 12.0 0.0 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein HA2 PF04408.23 ORY50994.1 - 1.2e-22 80.2 0.0 5e-22 78.2 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ORY50994.1 - 7.5e-15 55.2 0.0 1.6e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 ORY50995.1 - 2.8e-23 82.1 0.0 3.7e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DUF1126 PF06565.12 ORY50997.1 - 2.3e-96 316.7 4.2 2e-34 117.6 0.2 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain CHCH PF06747.13 ORY50998.1 - 1.9e-07 31.0 3.2 4e-07 30.0 3.3 1.5 1 1 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 ORY50998.1 - 0.0014 18.9 1.7 0.0024 18.2 1.7 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 ORY50998.1 - 0.13 12.3 3.7 4.8 7.3 0.3 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 ORY50998.1 - 0.18 11.9 2.6 0.28 11.2 2.6 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 ORY50998.1 - 0.45 10.9 4.9 6.2 7.2 0.4 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Pkinase PF00069.25 ORY50999.1 - 3.6e-53 180.6 0.0 8.3e-53 179.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY50999.1 - 2.6e-26 92.5 0.0 3.9e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 ORY50999.1 - 0.0017 17.9 0.1 0.0085 15.7 0.0 1.9 1 1 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 ORY50999.1 - 0.014 15.3 0.0 0.037 13.9 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family SE PF08491.10 ORY50999.1 - 0.097 11.7 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Squalene epoxidase DUF5360 PF17314.2 ORY51000.1 - 0.03 14.4 1.0 0.03 14.4 1.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5360) DUF4013 PF13197.6 ORY51000.1 - 0.037 13.9 3.6 0.047 13.5 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) DUF3810 PF12725.7 ORY51000.1 - 0.16 11.3 1.5 0.19 11.0 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Pkinase PF00069.25 ORY51001.1 - 3.1e-78 262.8 0.0 3.5e-78 262.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY51001.1 - 1.4e-34 119.5 0.0 1.8e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY51001.1 - 9.8e-05 21.4 0.0 0.0017 17.3 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 ORY51001.1 - 0.0005 19.5 0.0 0.0019 17.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORY51001.1 - 0.0013 18.7 0.0 0.0072 16.3 0.0 1.8 1 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 ORY51001.1 - 0.014 14.5 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 ORY51001.1 - 0.051 12.9 0.0 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 ORY51001.1 - 0.14 11.7 0.1 1.1 8.8 0.0 2.0 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 AAA_6 PF12774.7 ORY51002.1 - 5.8e-128 426.5 0.1 5.8e-127 423.2 0.0 2.8 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 ORY51002.1 - 1.5e-100 337.1 1.9 1.5e-100 337.1 1.9 4.0 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 ORY51002.1 - 9.3e-65 217.8 0.5 9.3e-65 217.8 0.5 3.8 3 1 0 3 3 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 ORY51002.1 - 6.3e-49 166.6 0.0 6.3e-49 166.6 0.0 3.6 5 0 0 5 5 4 1 P-loop containing dynein motor region D4 Dynein_heavy PF03028.15 ORY51002.1 - 8.6e-38 129.1 0.5 8.1e-35 119.5 0.0 4.9 5 0 0 5 5 5 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 ORY51002.1 - 3.6e-37 127.7 0.0 1.1e-36 126.2 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_C PF18199.1 ORY51002.1 - 7.5e-34 117.3 0.1 2.8e-33 115.5 0.1 2.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_5 PF07728.14 ORY51002.1 - 2.7e-33 114.9 0.0 1.6e-18 67.0 0.0 6.0 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) MT PF12777.7 ORY51002.1 - 2e-28 99.5 4.6 4.2e-28 98.4 4.6 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 ORY51002.1 - 2.5e-27 95.6 7.4 1.8e-25 89.5 0.0 3.6 4 0 0 4 4 3 2 P-loop containing dynein motor region DHC_N1 PF08385.12 ORY51002.1 - 2.6e-25 89.1 8.3 2.6e-25 89.1 8.3 3.3 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_16 PF13191.6 ORY51002.1 - 4e-07 30.6 0.0 0.032 14.6 0.0 4.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 ORY51002.1 - 5.5e-06 26.7 0.6 1.1 9.5 0.0 5.2 4 0 0 4 4 3 1 AAA domain AAA PF00004.29 ORY51002.1 - 1.1e-05 25.9 0.0 7.3 7.0 0.0 5.0 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 ORY51002.1 - 2.5e-05 24.2 0.0 0.033 14.1 0.0 3.1 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 ORY51002.1 - 8e-05 22.4 0.3 0.0095 15.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 ORY51002.1 - 0.00018 21.3 0.0 0.23 11.2 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 ORY51002.1 - 0.00081 19.9 0.0 0.18 12.4 0.0 3.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 ORY51002.1 - 0.0011 19.5 0.0 0.043 14.3 0.0 3.7 3 0 0 3 3 2 1 ABC transporter AAA_28 PF13521.6 ORY51002.1 - 0.0036 17.6 0.0 0.041 14.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 ORY51002.1 - 0.0051 16.5 0.0 1.6 8.4 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.12 ORY51002.1 - 0.0074 16.2 1.8 0.19 11.6 0.5 3.9 4 0 0 4 4 4 1 NACHT domain IstB_IS21 PF01695.17 ORY51002.1 - 0.023 14.5 0.1 10 5.8 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_29 PF13555.6 ORY51002.1 - 0.024 14.4 0.0 0.36 10.6 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain DegS PF05384.11 ORY51002.1 - 0.035 13.6 4.7 0.23 10.9 4.7 2.5 1 0 0 1 1 1 0 Sensor protein DegS DUF211 PF02680.14 ORY51002.1 - 0.047 13.9 0.0 0.24 11.6 0.0 2.3 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 AAA_19 PF13245.6 ORY51002.1 - 0.064 13.6 2.0 55 4.1 0.0 5.1 6 0 0 6 6 5 0 AAA domain T2SSE PF00437.20 ORY51002.1 - 0.066 12.3 0.0 0.26 10.3 0.0 2.0 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF3157 PF11355.8 ORY51002.1 - 0.08 12.5 0.1 0.36 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3157) AAA_33 PF13671.6 ORY51002.1 - 0.13 12.4 1.4 1 9.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 ORY51002.1 - 0.15 11.8 2.3 4.5 7.0 0.0 3.5 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein KxDL PF10241.9 ORY51002.1 - 1.6 9.1 5.5 4.3 7.7 0.2 4.6 3 0 0 3 3 2 0 Uncharacterized conserved protein DUF4164 PF13747.6 ORY51002.1 - 1.9 8.8 10.9 0.45 10.8 0.3 3.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) RIC1 PF07064.13 ORY51003.1 - 1e-52 179.1 3.6 2e-52 178.1 3.6 1.4 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 ORY51003.1 - 4e-05 23.8 0.4 0.0061 16.8 0.1 3.3 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_23 PF13489.6 ORY51004.1 - 1.1e-07 31.8 0.0 2e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY51004.1 - 1.5e-06 28.8 0.0 3.8e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY51004.1 - 3.1e-05 24.6 0.2 0.00017 22.2 0.2 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY51004.1 - 0.0006 20.5 0.1 0.0014 19.3 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY51004.1 - 0.016 15.0 0.1 1.4 8.7 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain CMAS PF02353.20 ORY51004.1 - 0.027 13.8 0.0 5.4 6.2 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase MMS1_N PF10433.9 ORY51005.1 - 3.4e-163 543.8 0.0 5.3e-163 543.1 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 ORY51005.1 - 2.7e-89 299.7 0.0 4.8e-88 295.6 0.0 2.4 2 0 0 2 2 2 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 ORY51005.1 - 0.15 12.3 0.0 0.73 10.2 0.0 2.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Nramp PF01566.18 ORY51006.1 - 4.6e-108 361.4 18.6 4.6e-108 361.4 18.6 1.8 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein Pro_isomerase PF00160.21 ORY51007.1 - 7.7e-33 114.0 0.0 9.8e-31 107.2 0.0 2.8 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GEMIN8 PF15348.6 ORY51007.1 - 0.076 13.3 15.8 0.14 12.4 15.8 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 PsbR PF04725.12 ORY51007.1 - 0.12 12.7 0.2 0.26 11.7 0.2 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa polypeptide PsbR Apt1 PF10351.9 ORY51007.1 - 0.25 10.2 21.9 0.34 9.7 21.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Zip PF02535.22 ORY51007.1 - 0.32 10.2 6.3 0.47 9.6 6.3 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter ORC6 PF05460.13 ORY51007.1 - 0.34 10.1 22.9 0.51 9.5 22.9 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SLC12 PF03522.15 ORY51007.1 - 0.72 8.8 10.9 0.99 8.4 10.9 1.3 1 0 0 1 1 1 0 Solute carrier family 12 SAPS PF04499.15 ORY51007.1 - 1.1 7.9 8.4 1.2 7.8 8.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NAM-associated PF14303.6 ORY51007.1 - 1.4 9.6 26.5 2.5 8.8 26.5 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Hamartin PF04388.12 ORY51007.1 - 1.6 7.3 13.9 2 7.0 13.9 1.1 1 0 0 1 1 1 0 Hamartin protein TMEM247 PF15444.6 ORY51007.1 - 1.8 8.6 8.8 2.7 8.0 8.8 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 QWRF PF04484.12 ORY51007.1 - 2.5 7.8 19.5 3.6 7.2 19.5 1.2 1 0 0 1 1 1 0 QWRF family Hid1 PF12722.7 ORY51007.1 - 3.5 5.6 16.3 4.5 5.3 16.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 ORY51007.1 - 3.8 7.5 10.0 5.8 6.9 10.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Smg8_Smg9 PF10220.9 ORY51007.1 - 4.8 5.4 12.9 6 5.0 12.9 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Macoilin PF09726.9 ORY51007.1 - 4.9 5.6 21.5 6.6 5.2 21.5 1.1 1 0 0 1 1 1 0 Macoilin family NARP1 PF12569.8 ORY51007.1 - 5.1 5.9 13.6 7.4 5.3 13.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SOBP PF15279.6 ORY51007.1 - 8.2 6.9 16.3 12 6.4 16.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Ndc1_Nup PF09531.10 ORY51007.1 - 9.4 4.8 16.4 11 4.5 16.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4524 PF15025.6 ORY51008.1 - 9.8e-11 41.6 0.1 4.9e-10 39.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4524) DUF4520 PF15016.6 ORY51008.1 - 0.0035 17.4 0.1 0.014 15.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4520) Metallophos PF00149.28 ORY51010.1 - 6.5e-16 59.4 0.3 9.7e-16 58.9 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.11 ORY51010.1 - 0.0012 17.2 0.1 0.016 13.5 0.0 2.3 3 0 0 3 3 3 1 Firmicute fructose-1,6-bisphosphatase SQS_PSY PF00494.19 ORY51011.1 - 2.6e-50 171.4 0.3 3.1e-50 171.1 0.3 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase PIP5K PF01504.18 ORY51012.1 - 1.1e-94 316.8 0.1 1.9e-94 315.9 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cys_Met_Meta_PP PF01053.20 ORY51013.1 - 3.1e-41 141.2 0.0 4.1e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 ORY51013.1 - 0.00086 18.6 0.0 0.0018 17.5 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II MPS-4 PF17523.2 ORY51013.1 - 0.017 15.2 0.0 0.051 13.7 0.0 1.8 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 ABC1 PF03109.16 ORY51014.1 - 0.082 13.1 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 ABC1 family ANAPC4_WD40 PF12894.7 ORY51015.1 - 0.069 13.5 0.0 2.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_S26 PF10502.9 ORY51016.1 - 1.1e-06 28.5 0.0 0.001 18.9 0.0 2.8 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 ORY51016.1 - 4.1e-06 26.6 0.0 7.7e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase S24-like Trns_repr_metal PF02583.17 ORY51017.1 - 0.039 14.3 0.4 0.74 10.2 0.0 2.5 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor DUF445 PF04286.12 ORY51017.1 - 0.062 13.1 1.7 0.16 11.8 1.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF445) Cnd1 PF12717.7 ORY51018.1 - 2.1e-54 183.9 12.3 1.5e-52 177.9 0.6 4.0 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 ORY51018.1 - 4.8e-34 117.6 0.7 2.2e-33 115.4 0.1 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 ORY51018.1 - 1e-09 37.8 0.1 0.32 11.4 0.0 7.1 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.6 ORY51018.1 - 1.7e-06 28.3 0.0 0.0043 17.4 0.0 4.2 5 1 0 5 5 5 1 HEAT repeats Adaptin_N PF01602.20 ORY51018.1 - 2.6e-05 23.0 13.2 0.0026 16.4 0.5 4.7 3 2 3 6 6 6 4 Adaptin N terminal region RTP1_C1 PF10363.9 ORY51018.1 - 4.4e-05 23.6 0.9 0.14 12.4 0.0 4.0 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 ORY51018.1 - 0.003 16.8 4.3 0.003 16.8 4.3 2.3 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain ENTH PF01417.20 ORY51018.1 - 0.0035 17.4 0.5 1.8 8.7 0.2 4.0 2 1 1 3 3 3 1 ENTH domain FANCI_S2 PF14676.6 ORY51018.1 - 0.19 12.0 3.1 11 6.2 0.1 4.4 3 2 0 4 4 4 0 FANCI solenoid 2 V-ATPase_H_N PF03224.14 ORY51018.1 - 4.2 6.6 8.9 0.64 9.3 0.5 3.3 5 0 0 5 5 5 0 V-ATPase subunit H Pyr_redox_2 PF07992.14 ORY51019.1 - 1.6e-43 149.0 1.5 2.2e-43 148.6 1.0 1.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 ORY51019.1 - 6.4e-34 116.5 2.8 1.7e-33 115.1 0.4 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 ORY51019.1 - 3.9e-15 56.2 1.2 7.9e-15 55.2 1.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY51019.1 - 9.7e-11 41.5 0.2 1.3e-10 41.1 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY51019.1 - 0.00038 19.7 0.0 0.00054 19.2 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 ORY51019.1 - 0.028 14.3 0.2 0.066 13.1 0.2 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Acyl-CoA_dh_1 PF00441.24 ORY51020.1 - 1.7e-38 132.2 1.4 2.4e-38 131.7 1.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 ORY51020.1 - 1.2e-23 83.1 0.1 2.2e-23 82.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 ORY51020.1 - 1.6e-17 63.4 0.0 3.2e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 ORY51020.1 - 3.6e-13 50.2 0.1 1.2e-12 48.5 0.1 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 ORY51020.1 - 3.1e-12 46.9 0.4 4.6e-12 46.4 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Rieske PF00355.26 ORY51021.1 - 2.2e-18 66.0 0.0 3.9e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 ORY51021.1 - 0.00041 20.4 0.0 0.00082 19.5 0.0 1.6 1 0 0 1 1 1 1 Pheophorbide a oxygenase VWA_2 PF13519.6 ORY51022.1 - 0.0049 17.5 0.2 0.024 15.3 0.1 2.2 1 1 1 2 2 2 1 von Willebrand factor type A domain Fanconi_A PF03511.14 ORY51022.1 - 0.091 12.7 0.0 0.31 11.0 0.0 1.8 2 0 0 2 2 2 0 Fanconi anaemia group A protein VWA PF00092.28 ORY51022.1 - 0.12 12.6 0.3 15 5.8 0.1 2.3 1 1 1 2 2 2 0 von Willebrand factor type A domain Fis1_TPR_C PF14853.6 ORY51022.1 - 0.15 12.2 0.0 0.8 9.8 0.0 2.1 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Siah-Interact_N PF09032.11 ORY51023.1 - 0.19 12.1 1.3 0.22 11.9 0.1 1.7 2 0 0 2 2 2 0 Siah interacting protein, N terminal Voltage_CLC PF00654.20 ORY51024.1 - 4.5e-37 128.1 22.8 7.6e-36 124.1 22.8 2.0 1 1 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 ORY51025.1 - 1.9e-09 37.8 0.0 1.8e-05 25.1 0.0 3.3 3 0 0 3 3 3 3 CBS domain P34-Arc PF04045.14 ORY51026.1 - 6.3e-100 333.8 0.0 7.9e-100 333.5 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc SH3_2 PF07653.17 ORY51027.1 - 0.081 12.6 0.0 1.3 8.8 0.0 2.2 1 1 1 2 2 2 0 Variant SH3 domain GATA PF00320.27 ORY51028.1 - 6.6e-11 41.6 11.8 1.3e-10 40.7 11.8 1.5 1 0 0 1 1 1 1 GATA zinc finger GATA PF00320.27 ORY51031.1 - 1e-08 34.6 2.3 1.8e-08 33.9 2.3 1.4 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.18 ORY51031.1 - 0.00036 20.6 0.7 0.00063 19.8 0.7 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Vps36-NZF-N PF16988.5 ORY51031.1 - 0.17 11.3 1.6 0.39 10.1 1.3 1.8 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain GATA PF00320.27 ORY51033.1 - 2.2e-10 39.9 2.2 4.1e-10 39.1 2.2 1.5 1 0 0 1 1 1 1 GATA zinc finger Zn-ribbon_8 PF09723.10 ORY51033.1 - 0.013 15.6 0.9 0.036 14.2 0.2 2.0 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2HE PF16278.5 ORY51033.1 - 0.1 13.0 0.6 1.4 9.4 0.1 2.6 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger A2L_zn_ribbon PF08792.10 ORY51033.1 - 0.26 11.1 0.7 2 8.2 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain Metal_resist PF13801.6 ORY51033.1 - 3.6 7.8 8.7 3.1 8.0 5.0 2.3 2 0 0 2 2 2 0 Heavy-metal resistance GATA PF00320.27 ORY51035.1 - 6.5e-13 48.1 4.9 1.1e-12 47.3 4.9 1.4 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.18 ORY51035.1 - 0.016 15.3 0.1 0.027 14.5 0.1 1.4 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf eIF-5_eIF-2B PF01873.17 ORY51035.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.12 ORY51035.1 - 0.45 10.1 3.2 3.1 7.4 3.4 2.1 1 1 1 2 2 2 0 TFIIB zinc-binding Auto_anti-p27 PF06677.12 ORY51035.1 - 0.73 10.0 2.7 0.5 10.6 0.9 1.7 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) SET PF00856.28 ORY51036.1 - 1.5e-06 28.7 0.1 1e-05 26.0 0.1 2.0 1 1 0 1 1 1 1 SET domain SelP_N PF04592.14 ORY51037.1 - 0.46 9.8 12.2 0.63 9.4 12.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Macoilin PF09726.9 ORY51037.1 - 1.9 7.0 7.9 2 6.9 7.9 1.0 1 0 0 1 1 1 0 Macoilin family GATA PF00320.27 ORY51038.1 - 5.8e-14 51.4 5.3 1.1e-13 50.6 5.3 1.5 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.18 ORY51038.1 - 0.049 13.7 0.1 0.049 13.7 0.1 3.5 3 1 0 3 3 3 0 Putative GTPase activating protein for Arf TF_Zn_Ribbon PF08271.12 ORY51038.1 - 0.23 11.0 0.6 0.42 10.2 0.6 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding F_bP_aldolase PF01116.20 ORY51041.1 - 2.1e-05 24.1 4.5 3.5 7.0 0.1 4.6 2 1 3 5 5 5 5 Fructose-bisphosphate aldolase class-II DUF5490 PF17593.2 ORY51041.1 - 0.7 10.0 0.0 0.7 10.0 0.0 11.5 3 2 10 13 13 13 0 Family of unknown function (DUF5490) Myotoxins PF00819.17 ORY51041.1 - 6.3 7.2 34.5 64 3.9 0.3 9.7 3 2 8 11 11 11 0 Myotoxin, crotamine WD40 PF00400.32 ORY51042.1 - 6.7e-24 83.7 22.0 0.00037 21.2 1.4 11.3 12 0 0 12 12 12 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY51042.1 - 2.7e-08 34.0 5.2 0.037 14.3 0.0 6.5 4 2 4 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY51042.1 - 0.0058 15.6 0.1 28 3.5 0.0 4.2 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORY51042.1 - 0.054 12.1 3.5 0.59 8.7 0.0 2.9 3 0 0 3 3 3 0 Nucleoporin Nup120/160 MFS_1 PF07690.16 ORY51043.1 - 1.1e-26 93.7 42.0 1.1e-20 73.9 17.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY51043.1 - 6e-11 41.9 22.0 2.8e-08 33.1 3.9 2.2 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 ORY51043.1 - 7.5e-10 37.9 9.6 6.8e-06 24.9 0.0 2.6 2 1 1 3 3 3 2 MFS/sugar transport protein ATG22 PF11700.8 ORY51043.1 - 5.1e-05 22.1 0.8 0.0024 16.6 0.0 2.3 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like BT1 PF03092.16 ORY51043.1 - 0.00026 19.4 6.6 0.0079 14.5 2.9 2.9 2 1 1 3 3 3 2 BT1 family MFS_1_like PF12832.7 ORY51043.1 - 0.011 14.6 10.2 0.036 12.9 0.5 3.6 3 1 1 4 4 4 0 MFS_1 like family FtsJ PF01728.19 ORY51044.1 - 8.6e-53 179.1 0.0 1.6e-52 178.2 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.12 ORY51044.1 - 1.2e-51 175.4 43.9 1.2e-51 175.4 43.9 4.2 3 2 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.8 ORY51044.1 - 9.5e-35 119.8 18.3 9.5e-35 119.8 18.3 5.5 4 1 0 4 4 4 1 Domain of unknown function (DUF3381) Pkinase PF00069.25 ORY51045.1 - 2.8e-68 230.1 0.0 3.3e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY51045.1 - 5.5e-36 124.2 0.0 6.9e-36 123.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY51045.1 - 4e-09 36.2 0.0 3.9e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 ORY51045.1 - 1.5e-05 25.0 0.0 0.0001 22.3 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY51045.1 - 5.9e-05 22.2 0.0 7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 ORY51045.1 - 0.0001 22.0 0.1 0.2 11.2 0.0 2.3 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 ORY51045.1 - 0.00079 19.1 0.1 0.0026 17.4 0.0 1.6 1 1 0 2 2 2 1 RIO1 family Kdo PF06293.14 ORY51045.1 - 0.0016 17.8 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 ORY51045.1 - 0.0057 15.8 0.0 0.0099 15.0 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 ORY51045.1 - 0.072 11.9 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase SPX PF03105.19 ORY51047.1 - 7.5 6.4 10.2 8.8 6.1 10.2 1.2 1 0 0 1 1 1 0 SPX domain Cellulase PF00150.18 ORY51048.1 - 1.9e-05 24.3 0.0 0.00064 19.2 0.0 2.2 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_cc PF11790.8 ORY51048.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core FAD_binding_3 PF01494.19 ORY51049.1 - 1.4e-26 93.6 0.3 2e-20 73.3 0.2 3.1 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 ORY51049.1 - 2.8e-09 36.6 1.3 0.00094 18.5 0.1 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY51049.1 - 1.4e-06 28.1 0.0 0.029 14.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 ORY51049.1 - 1.3e-05 25.3 0.0 3.5e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 ORY51049.1 - 0.00011 21.2 0.2 0.024 13.5 0.0 2.5 3 0 0 3 3 3 2 Tryptophan halogenase SE PF08491.10 ORY51049.1 - 0.00016 20.9 0.0 0.00099 18.2 0.0 2.0 1 1 0 1 1 1 1 Squalene epoxidase FAD_binding_2 PF00890.24 ORY51049.1 - 0.001 18.3 0.1 0.003 16.7 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 ORY51049.1 - 0.0012 18.0 1.3 0.012 14.6 0.1 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.14 ORY51049.1 - 0.0013 17.5 0.2 0.24 10.1 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.22 ORY51049.1 - 0.0035 16.5 0.1 0.0046 16.1 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 ORY51049.1 - 0.0037 16.6 0.2 0.085 12.1 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 ORY51049.1 - 0.014 14.7 0.1 0.052 12.8 0.1 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 ORY51049.1 - 0.11 13.0 0.4 7.1 7.3 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 ORY51050.1 - 1.4e-68 231.1 0.0 1.8e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY51050.1 - 7.5e-34 117.2 0.0 9.5e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY51050.1 - 1.1e-06 28.2 0.0 9.8e-05 21.8 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 ORY51050.1 - 7.6e-05 21.8 0.0 0.0001 21.4 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 ORY51050.1 - 0.0012 18.5 0.0 0.62 9.7 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 ORY51050.1 - 0.005 16.8 0.1 0.11 12.4 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY51050.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MFS_1 PF07690.16 ORY51053.1 - 2.2e-14 53.2 28.6 1.2e-08 34.3 7.5 1.9 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 ORY51053.1 - 0.00072 18.5 5.1 0.0071 15.2 2.6 2.8 2 1 0 2 2 2 1 MFS_1 like family MFS_2 PF13347.6 ORY51053.1 - 0.0028 16.3 7.2 0.019 13.6 6.2 2.0 1 1 1 2 2 2 2 MFS/sugar transport protein CAP_C PF08603.11 ORY51053.1 - 0.33 10.5 2.5 0.18 11.4 0.4 1.6 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) C terminal Voltage_CLC PF00654.20 ORY51054.1 - 5.2e-55 187.1 1.3 6.4e-47 160.5 0.0 2.5 2 1 0 2 2 2 2 Voltage gated chloride channel Dak2 PF02734.17 ORY51054.1 - 0.042 13.7 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 DAK2 domain Voltage_CLC PF00654.20 ORY51055.1 - 5.1e-58 197.0 14.5 4.3e-47 161.1 3.9 2.6 2 1 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 ORY51055.1 - 8.8e-09 35.7 0.1 2.3e-06 27.9 0.1 3.1 3 0 0 3 3 3 1 CBS domain BRX_assoc PF16627.5 ORY51055.1 - 0.14 12.4 0.5 0.44 10.7 0.5 1.8 1 0 0 1 1 1 0 Unstructured region between BRX_N and BRX domain LRR_4 PF12799.7 ORY51056.1 - 0.00026 21.3 0.3 0.0023 18.3 0.3 2.2 1 1 1 2 2 2 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY51056.1 - 0.0014 18.5 4.0 0.014 15.4 0.1 3.1 3 0 0 3 3 3 1 Leucine Rich repeat LRR_8 PF13855.6 ORY51056.1 - 0.0023 17.7 0.2 0.0059 16.3 0.1 1.7 2 0 0 2 2 2 1 Leucine rich repeat SH3_1 PF00018.28 ORY51056.1 - 0.0024 17.4 0.0 0.0046 16.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY51056.1 - 0.0028 17.5 0.0 0.0057 16.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain FA_desaturase PF00487.24 ORY51057.1 - 2.4e-24 86.6 21.9 8.7e-24 84.7 21.9 1.8 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 ORY51057.1 - 1e-05 25.8 0.0 2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Rieske PF00355.26 ORY51058.1 - 3.4e-16 59.0 0.0 6.1e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 ORY51058.1 - 4.5e-10 39.5 0.0 1.3e-09 38.1 0.0 1.7 2 0 0 2 2 2 1 Pheophorbide a oxygenase Rieske PF00355.26 ORY51059.1 - 1.9e-16 59.8 0.0 3.9e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 ORY51059.1 - 7.8e-08 32.4 0.1 3.5e-07 30.3 0.0 2.1 3 0 0 3 3 3 1 Pheophorbide a oxygenase Nramp PF01566.18 ORY51060.1 - 7.6e-105 350.8 16.6 2e-104 349.4 16.6 1.7 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein FAD_binding_3 PF01494.19 ORY51061.1 - 2.2e-15 56.8 3.4 4.5e-10 39.3 0.1 3.2 2 1 1 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 ORY51061.1 - 2e-06 27.9 0.0 9.7e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 ORY51061.1 - 0.00057 19.2 0.0 0.011 15.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY51061.1 - 0.0025 17.4 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 ORY51061.1 - 0.013 14.6 0.1 0.019 14.1 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FMO-like PF00743.19 ORY51061.1 - 0.016 13.7 0.0 0.022 13.2 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like FAD_binding_2 PF00890.24 ORY51061.1 - 0.03 13.4 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 ORY51061.1 - 0.053 13.2 0.1 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 ORY51061.1 - 0.077 11.7 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein SUR7 PF06687.12 ORY51063.1 - 0.0079 15.9 2.9 0.0079 15.9 2.9 2.1 1 1 2 3 3 3 1 SUR7/PalI family CitMHS PF03600.16 ORY51063.1 - 0.02 14.1 0.5 0.02 14.1 0.5 1.4 1 1 0 1 1 1 0 Citrate transporter DnaJ PF00226.31 ORY51064.1 - 1.3e-23 82.9 0.7 1.3e-23 82.9 0.7 2.2 3 0 0 3 3 3 1 DnaJ domain TPR_1 PF00515.28 ORY51064.1 - 6.5e-09 35.2 0.0 0.00096 18.9 0.0 4.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY51064.1 - 9.8e-05 22.2 7.3 0.019 15.1 0.0 5.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY51064.1 - 0.0056 16.8 4.6 0.053 13.8 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY51064.1 - 0.16 12.4 11.1 2.9 8.5 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 ORY51064.1 - 0.24 11.1 5.7 25 4.7 0.2 4.6 4 0 0 4 4 4 0 TPR repeat TPR_7 PF13176.6 ORY51064.1 - 0.69 10.1 2.6 5 7.4 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY51064.1 - 1.1 9.9 15.5 17 6.1 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY51064.1 - 1.2 9.5 8.5 22 5.4 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY51064.1 - 8.4 7.5 14.4 14 6.8 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat LRR_4 PF12799.7 ORY51065.1 - 9.8e-12 44.9 4.4 2e-05 24.8 1.5 4.0 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY51065.1 - 4.6e-11 42.3 6.7 1e-06 28.4 0.5 3.3 2 1 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 ORY51065.1 - 5.3e-07 29.3 8.5 0.038 14.5 1.0 5.7 5 0 0 5 5 5 1 Leucine Rich Repeat F-box PF00646.33 ORY51065.1 - 0.021 14.7 0.5 0.043 13.7 0.5 1.5 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 ORY51065.1 - 0.027 14.4 0.9 0.069 13.1 0.9 1.7 1 0 0 1 1 1 0 F-box-like LRR_6 PF13516.6 ORY51065.1 - 0.056 13.5 9.5 0.83 9.9 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich repeat L27_2 PF09045.10 ORY51066.1 - 0.13 12.2 0.2 0.24 11.4 0.2 1.4 1 0 0 1 1 1 0 L27_2 Zn_clus PF00172.18 ORY51067.1 - 5.5e-10 39.2 30.0 3.2e-06 27.1 5.2 2.9 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_dh PF01619.18 ORY51069.1 - 1e-53 182.8 0.0 2.3e-43 148.8 0.0 2.9 2 1 1 3 3 3 2 Proline dehydrogenase FAM91_C PF14648.6 ORY51069.1 - 0.039 12.8 0.0 0.057 12.2 0.0 1.1 1 0 0 1 1 1 0 FAM91 C-terminus LRR_8 PF13855.6 ORY51070.1 - 1.4e-09 37.5 7.2 5.9e-05 22.7 2.6 3.0 1 1 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY51070.1 - 2.6e-08 34.0 11.8 0.00015 22.1 3.7 4.2 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY51070.1 - 0.0029 17.9 12.6 6.3 7.8 0.7 5.8 5 1 1 6 6 6 2 Leucine Rich Repeat LRR_9 PF14580.6 ORY51070.1 - 0.14 11.6 0.2 0.21 11.0 0.2 1.3 1 0 0 1 1 1 0 Leucine-rich repeat LRR_6 PF13516.6 ORY51070.1 - 0.24 11.5 0.1 0.24 11.5 0.1 4.2 5 0 0 5 5 5 0 Leucine Rich repeat Isochorismatase PF00857.20 ORY51071.1 - 2.4e-16 60.4 0.3 2.8e-14 53.7 0.3 2.5 1 1 0 1 1 1 1 Isochorismatase family Ish1 PF10281.9 ORY51071.1 - 0.021 15.1 0.0 0.24 11.7 0.0 2.2 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Glyco_transf_90 PF05686.12 ORY51073.1 - 5.7e-12 45.3 0.2 4.6e-10 39.0 0.1 2.0 2 0 0 2 2 2 2 Glycosyl transferase family 90 ANAPC4_WD40 PF12894.7 ORY51077.1 - 0.087 13.1 0.0 0.94 9.8 0.0 2.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RbcS PF12338.8 ORY51078.1 - 0.055 13.7 0.3 0.12 12.6 0.3 1.5 1 0 0 1 1 1 0 Ribulose-1,5-bisphosphate carboxylase small subunit DUF4336 PF14234.6 ORY51079.1 - 0.00063 19.0 0.0 0.012 14.8 0.0 2.2 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) FAM163 PF15069.6 ORY51080.1 - 0.037 14.5 0.4 0.14 12.6 0.4 1.9 1 0 0 1 1 1 0 FAM163 family ATP-sulfurylase PF01747.17 ORY51081.1 - 5.2e-78 261.4 0.2 2.7e-76 255.8 0.2 2.2 1 1 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 ORY51081.1 - 3e-52 176.7 0.0 4.6e-52 176.1 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 ORY51081.1 - 1.1e-48 164.9 0.0 2e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain F5_F8_type_C PF00754.25 ORY51082.1 - 1.1e-06 28.7 0.1 1.9e-06 28.0 0.1 1.4 1 1 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.13 ORY51082.1 - 0.0094 16.0 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Pho88 PF10032.9 ORY51083.1 - 5.5e-10 38.8 0.2 6.9e-05 22.2 0.0 2.2 1 1 1 2 2 2 2 Phosphate transport (Pho88) DUF4083 PF13314.6 ORY51083.1 - 0.16 11.9 1.0 0.36 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Nipped-B_C PF12830.7 ORY51083.1 - 0.82 9.6 3.1 0.94 9.4 3.1 1.3 1 1 0 1 1 1 0 Sister chromatid cohesion C-terminus SH3_9 PF14604.6 ORY51084.1 - 8.5e-05 22.3 0.0 0.0001 22.1 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY51084.1 - 0.00077 19.0 0.0 0.00099 18.7 0.0 1.2 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY51084.1 - 0.0021 17.7 0.0 0.0026 17.4 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain DUF5599 PF18141.1 ORY51084.1 - 0.065 13.5 0.0 0.077 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5599) DUF4926 PF16277.5 ORY51084.1 - 0.13 11.7 0.0 1.1 8.7 0.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4926) CDC24 PF06395.11 ORY51084.1 - 0.13 12.5 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 CDC24 Calponin WD40 PF00400.32 ORY51085.1 - 4.9e-28 96.8 16.5 2e-05 25.3 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY51085.1 - 5.3e-08 33.1 1.1 0.015 15.6 0.1 4.7 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 ORY51085.1 - 3.1e-06 27.0 4.1 0.018 14.7 0.7 2.4 2 0 0 2 2 2 2 PQQ-like domain Nup160 PF11715.8 ORY51085.1 - 7e-06 25.0 7.0 1.3 7.6 0.0 4.6 3 2 2 5 5 5 4 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY51085.1 - 2.2e-05 24.0 0.0 9.6e-05 21.9 0.0 1.9 1 1 0 1 1 1 1 WD40-like domain PQQ_3 PF13570.6 ORY51085.1 - 0.00065 20.1 1.7 1.3 9.6 0.0 4.3 3 1 1 4 4 4 1 PQQ-like domain DUF5046 PF16465.5 ORY51085.1 - 0.03 13.8 1.1 6.1 6.2 0.0 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF5046) Cellulase PF00150.18 ORY51086.1 - 1.7e-20 73.6 0.0 2.6e-19 69.7 0.0 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 ORY51086.1 - 0.0016 19.0 0.0 0.0038 17.7 0.0 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Lipase_GDSL_2 PF13472.6 ORY51087.1 - 6.3e-17 62.5 0.0 1.2e-16 61.7 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY51087.1 - 1.3e-12 48.2 0.0 1.7e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase PseudoU_synth_1 PF01416.20 ORY51088.1 - 0.042 14.3 0.0 0.14 12.7 0.0 1.9 2 0 0 2 2 2 0 tRNA pseudouridine synthase DUF3467 PF11950.8 ORY51088.1 - 0.11 12.7 0.1 0.22 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3467) WD40 PF00400.32 ORY51089.1 - 1.2e-32 111.4 19.4 3.8e-06 27.5 0.5 8.2 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY51089.1 - 9.4e-07 29.0 0.4 0.41 11.0 0.0 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DNA_pol_phi PF04931.13 ORY51089.1 - 0.00034 18.9 5.1 0.00034 18.9 5.1 2.1 2 0 0 2 2 2 1 DNA polymerase phi F-box-like PF12937.7 ORY51089.1 - 0.0069 16.2 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like SDA1 PF05285.12 ORY51089.1 - 2 7.8 14.8 0.16 11.4 2.5 2.2 2 0 0 2 2 2 0 SDA1 Flavodoxin_1 PF00258.25 ORY51090.1 - 0.0035 17.6 0.0 0.0044 17.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin MSA-2c PF12238.8 ORY51090.1 - 5.8 6.9 6.8 7 6.6 6.8 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c FAD_binding_3 PF01494.19 ORY51093.1 - 6.7e-08 32.2 0.0 8e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 ORY51093.1 - 0.15 11.1 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase FAD_binding_3 PF01494.19 ORY51094.1 - 3.7e-08 33.0 0.1 1.1e-07 31.4 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain PRD_Mga PF08270.11 ORY51095.1 - 0.046 13.4 0.2 0.079 12.6 0.2 1.5 1 1 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain GDC-P PF02347.16 ORY51095.1 - 0.24 10.2 1.9 1.1 8.0 0.1 2.0 1 1 0 2 2 2 0 Glycine cleavage system P-protein ABC_tran PF00005.27 ORY51096.1 - 4.1e-32 111.6 0.1 1.7e-19 70.7 0.0 3.4 3 0 0 3 3 3 3 ABC transporter ABC_membrane PF00664.23 ORY51096.1 - 5.7e-23 81.9 28.6 2e-12 47.3 15.9 4.5 2 2 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 ORY51096.1 - 3.8e-07 29.8 0.0 0.055 12.9 0.0 3.1 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ORY51096.1 - 0.00032 20.7 0.0 0.00059 19.8 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 ORY51096.1 - 0.00052 19.2 0.0 0.00091 18.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 ORY51096.1 - 0.0026 18.0 0.1 0.019 15.3 0.0 2.4 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.23 ORY51096.1 - 0.0045 17.0 0.0 0.015 15.4 0.0 1.8 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.6 ORY51096.1 - 0.0056 16.4 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 ORY51096.1 - 0.0057 16.5 0.6 0.1 12.4 0.2 2.4 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORY51096.1 - 0.0092 16.4 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_PrkA PF08298.11 ORY51096.1 - 0.021 13.7 0.0 0.036 13.0 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain cobW PF02492.19 ORY51096.1 - 0.056 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 ORY51096.1 - 0.085 12.6 0.0 0.52 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORY51096.1 - 0.12 11.8 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region FAD_binding_1 PF00667.20 ORY51097.1 - 8.1e-45 153.1 0.2 2.7e-44 151.4 0.2 1.8 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 ORY51097.1 - 4.8e-25 88.4 0.9 8.2e-25 87.7 0.9 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 ORY51097.1 - 7e-11 42.7 0.0 5.1e-10 40.0 0.0 2.5 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain Velvet PF11754.8 ORY51098.1 - 0.0058 16.6 1.3 0.0064 16.5 1.3 1.1 1 0 0 1 1 1 1 Velvet factor Retinal PF15449.6 ORY51098.1 - 9.9 3.8 14.6 11 3.6 14.6 1.0 1 0 0 1 1 1 0 Retinal protein Ank_2 PF12796.7 ORY51099.1 - 1.8e-09 38.1 0.0 9.9e-06 26.1 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY51099.1 - 1.3e-05 25.2 0.1 13 6.7 0.0 6.0 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 ORY51099.1 - 2.6e-05 24.4 0.0 1.2 9.5 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY51099.1 - 0.00024 21.4 0.1 0.51 10.9 0.0 4.5 3 1 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 ORY51100.1 - 6e-11 42.8 0.0 1.3e-05 25.7 0.0 3.4 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY51100.1 - 3.1e-05 24.2 0.1 0.29 11.5 0.0 3.5 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY51100.1 - 4.4e-05 23.6 0.5 16 6.5 0.0 5.0 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 ORY51100.1 - 0.039 14.5 0.0 43 4.9 0.0 3.6 3 1 1 4 4 4 0 Ankyrin repeats (many copies) MiaE_2 PF13794.6 ORY51100.1 - 0.092 12.4 0.0 12 5.5 0.0 2.4 3 0 0 3 3 3 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like Radical_SAM_N PF08497.10 ORY51101.1 - 0.11 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Radical SAM N-terminal Ribosomal_L29 PF00831.23 ORY51102.1 - 0.074 13.0 0.1 0.5 10.4 0.0 2.2 2 0 0 2 2 2 0 Ribosomal L29 protein DUF1192 PF06698.11 ORY51102.1 - 0.11 12.6 0.1 0.23 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Rab_bind PF16704.5 ORY51102.1 - 0.16 12.0 1.5 0.27 11.3 0.3 2.0 2 0 0 2 2 2 0 Rab binding domain ABC_tran PF00005.27 ORY51103.1 - 4.8e-47 159.9 0.0 6.1e-25 88.3 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 ORY51103.1 - 1.2e-45 156.3 28.8 4.9e-27 95.3 8.8 3.2 2 1 1 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 ORY51103.1 - 2.8e-09 36.8 0.2 0.059 12.8 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY51103.1 - 3.1e-08 33.2 0.1 0.011 15.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY51103.1 - 1.3e-07 32.1 0.2 0.0041 17.5 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 ORY51103.1 - 1.7e-07 31.4 0.7 0.17 11.6 0.2 3.4 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORY51103.1 - 1.7e-07 31.3 0.8 0.00042 20.3 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ORY51103.1 - 6.9e-07 29.3 0.0 0.0084 16.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 ORY51103.1 - 3.4e-06 27.2 0.1 0.02 14.9 0.0 2.8 2 0 0 2 2 2 2 Dynamin family AAA_22 PF13401.6 ORY51103.1 - 6.6e-06 26.4 0.1 0.025 14.8 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.6 ORY51103.1 - 3.9e-05 23.5 0.0 0.25 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 ORY51103.1 - 7.6e-05 23.3 0.3 0.52 10.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain T2SSE PF00437.20 ORY51103.1 - 8.8e-05 21.7 0.5 0.0017 17.5 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_PrkA PF08298.11 ORY51103.1 - 0.00014 20.9 0.0 0.018 13.9 0.0 2.2 2 0 0 2 2 2 1 PrkA AAA domain AAA_7 PF12775.7 ORY51103.1 - 0.0013 18.2 0.1 0.64 9.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region cobW PF02492.19 ORY51103.1 - 0.0026 17.4 0.3 0.15 11.7 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 ORY51103.1 - 0.0032 17.3 0.1 3.1 7.4 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain DUF815 PF05673.13 ORY51103.1 - 0.004 16.4 0.0 0.72 9.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 ORY51103.1 - 0.0059 16.0 0.1 1.7 8.0 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family KAP_NTPase PF07693.14 ORY51103.1 - 0.0088 15.3 0.0 4.9 6.3 0.0 2.8 2 1 1 3 3 3 1 KAP family P-loop domain Zeta_toxin PF06414.12 ORY51103.1 - 0.038 13.2 0.2 1.7 7.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 ORY51103.1 - 0.043 14.2 0.0 5.8 7.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 ORY51103.1 - 0.047 13.6 0.1 14 5.6 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Guanylate_kin PF00625.21 ORY51103.1 - 0.048 13.4 0.1 2.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Guanylate kinase TrwB_AAD_bind PF10412.9 ORY51103.1 - 0.051 12.5 0.5 5.5 5.8 0.2 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP_bind_1 PF03029.17 ORY51103.1 - 0.058 13.2 0.0 4.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 ORY51103.1 - 0.064 13.3 0.0 5.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_27 PF13514.6 ORY51103.1 - 0.079 12.5 0.0 6.7 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ORY51103.1 - 0.088 12.4 0.0 8.1 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 ORY51103.1 - 0.094 11.7 0.5 10 5.0 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Adeno_IVa2 PF02456.15 ORY51103.1 - 0.14 10.9 1.0 5.8 5.6 0.0 2.9 3 0 0 3 3 3 0 Adenovirus IVa2 protein AAA_18 PF13238.6 ORY51103.1 - 0.16 12.5 0.0 17 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 ORY51103.1 - 0.16 12.0 0.1 1.1 9.3 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain EMG1 PF03587.14 ORY51105.1 - 2.5e-80 268.7 0.0 2.9e-80 268.5 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Terminase_6C PF17289.2 ORY51106.1 - 0.01 16.0 0.9 0.036 14.1 0.2 2.3 1 1 0 2 2 2 0 Terminase RNaseH-like domain HTH_37 PF13744.6 ORY51106.1 - 0.039 13.9 0.4 0.039 13.9 0.4 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain Pox_A_type_inc PF04508.12 ORY51106.1 - 0.14 12.1 9.3 22 5.1 0.0 5.5 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat ArsC PF03960.15 ORY51106.1 - 0.17 11.9 0.5 0.95 9.5 0.5 2.3 1 0 0 1 1 1 0 ArsC family CHASE8 PF17152.4 ORY51106.1 - 1.1 9.6 5.7 5.5 7.3 0.5 3.2 3 0 0 3 3 3 0 Periplasmic sensor domain Glu-tRNAGln PF02686.15 ORY51106.1 - 3.7 7.9 8.9 23 5.3 0.1 4.1 4 1 0 4 4 4 0 Glu-tRNAGln amidotransferase C subunit T7SS_ESX_EspC PF10824.8 ORY51106.1 - 5.7 7.5 9.9 0.98 9.9 4.2 2.6 3 0 0 3 3 3 0 Excreted virulence factor EspC, type VII ESX diderm NYD-SP28 PF14772.6 ORY51106.1 - 7.9 6.6 30.1 3.3 7.8 9.5 5.1 3 2 1 4 4 4 0 Sperm tail DUF4208 PF13907.6 ORY51106.1 - 8.6 6.9 10.3 0.96 9.9 0.4 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4208) OrfB_IS605 PF01385.19 ORY51107.1 - 0.022 15.0 4.5 0.022 15.0 4.5 3.0 1 1 1 2 2 2 0 Probable transposase NAD_binding_6 PF08030.12 ORY51107.1 - 4.4 7.4 8.2 0.31 11.1 0.1 2.6 2 1 0 2 2 2 0 Ferric reductase NAD binding domain Metallophos PF00149.28 ORY51108.1 - 1.1e-05 26.1 0.6 2.8e-05 24.7 0.6 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 ORY51108.1 - 0.0062 16.7 0.0 0.016 15.4 0.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Robl_LC7 PF03259.17 ORY51111.1 - 3.6e-18 65.1 0.1 4e-18 65.0 0.1 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain DNA_gyraseA_C PF03989.13 ORY51111.1 - 0.046 13.2 0.0 0.49 9.9 0.0 2.1 1 1 0 1 1 1 0 DNA gyrase C-terminal domain, beta-propeller ACBP PF00887.19 ORY51112.1 - 8.9e-30 102.8 1.0 9.6e-30 102.6 1.0 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein WD40 PF00400.32 ORY51113.1 - 9.5e-15 54.7 7.0 1.9 9.5 0.0 9.6 10 0 0 10 10 10 7 WD domain, G-beta repeat CK_II_beta PF01214.18 ORY51114.1 - 4e-66 222.3 0.2 4e-65 219.0 0.2 1.9 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Mu-like_Com PF10122.9 ORY51114.1 - 0.025 14.0 2.8 0.046 13.2 2.8 1.4 1 0 0 1 1 1 0 Mu-like prophage protein Com Kinocilin PF15033.6 ORY51114.1 - 0.047 13.3 0.0 0.1 12.2 0.0 1.5 2 0 0 2 2 2 0 Kinocilin protein Ribonuc_2-5A PF06479.12 ORY51114.1 - 0.088 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Ribonuclease 2-5A MFS_1 PF07690.16 ORY51116.1 - 1.5e-16 60.3 34.7 1.3e-07 30.9 18.7 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF2897 PF11446.8 ORY51117.1 - 0.089 12.7 0.3 0.18 11.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) LapA_dom PF06305.11 ORY51117.1 - 0.1 12.5 0.1 0.16 11.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Nucleo_P87 PF07267.11 ORY51120.1 - 3.2 6.5 4.2 3.8 6.2 4.2 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 LRR_4 PF12799.7 ORY51121.1 - 0.00094 19.5 7.6 0.00094 19.5 7.6 2.4 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) F-box PF00646.33 ORY51121.1 - 0.00097 19.0 0.0 0.003 17.4 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY51121.1 - 0.0022 17.8 0.0 0.0067 16.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 ORY51121.1 - 0.038 13.8 12.0 0.031 14.0 9.3 2.2 2 1 0 2 2 2 0 Leucine rich repeat LRR_8 PF13855.6 ORY51124.1 - 2.3e-11 43.3 18.3 6.4e-05 22.6 1.7 3.7 2 2 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 ORY51124.1 - 4.9e-09 36.3 26.4 0.00077 19.8 2.5 5.5 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY51124.1 - 0.0014 18.9 23.0 1.7 9.5 0.1 7.0 6 2 1 7 7 7 2 Leucine Rich Repeat F-box PF00646.33 ORY51124.1 - 0.0018 18.1 0.0 0.0071 16.2 0.0 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY51124.1 - 0.0056 16.6 0.1 0.033 14.1 0.0 2.3 2 0 0 2 2 2 1 F-box-like Septin PF00735.18 ORY51125.1 - 5.2e-84 281.9 0.4 3.9e-72 242.9 0.0 2.1 1 1 1 2 2 2 2 Septin RsgA_GTPase PF03193.16 ORY51125.1 - 0.00022 21.2 0.2 0.00077 19.4 0.1 1.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 ORY51125.1 - 0.0028 17.7 0.4 0.0058 16.7 0.4 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 ORY51125.1 - 0.0055 17.1 0.1 0.016 15.6 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 ORY51125.1 - 0.0059 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family NB-ARC PF00931.22 ORY51125.1 - 0.006 15.8 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.27 ORY51125.1 - 0.0063 17.0 0.0 0.01 16.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 ORY51125.1 - 0.031 14.6 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AIG1 PF04548.16 ORY51125.1 - 0.057 12.7 0.1 0.1 11.9 0.1 1.4 1 0 0 1 1 1 0 AIG1 family RNA_helicase PF00910.22 ORY51125.1 - 0.17 12.3 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase MFS_1 PF07690.16 ORY51126.1 - 4.2e-20 72.0 27.1 1.5e-17 63.6 23.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY51126.1 - 6e-09 35.0 12.9 2.1e-08 33.1 11.8 2.0 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.16 ORY51127.1 - 1.9e-28 99.4 31.4 1.9e-28 99.4 31.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 ORY51127.1 - 0.0025 16.3 0.7 0.0025 16.3 0.7 2.1 2 1 0 2 2 2 1 Transmembrane secretion effector Pkinase PF00069.25 ORY51128.1 - 1.8e-54 184.9 0.0 7.6e-54 182.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY51128.1 - 1.8e-20 73.3 0.5 2.4e-19 69.6 0.2 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Chloroplast_duf PF14476.6 ORY51128.1 - 0.1 11.6 0.1 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 Petal formation-expressed bZIP_1 PF00170.21 ORY51129.1 - 0.0005 20.1 7.0 0.00086 19.4 7.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor MPS2 PF17060.5 ORY51129.1 - 0.25 10.6 3.1 0.31 10.2 3.1 1.0 1 0 0 1 1 1 0 Monopolar spindle protein 2 Gti1_Pac2 PF09729.9 ORY51130.1 - 1.8e-16 60.7 0.0 2.3e-13 50.6 0.0 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Nitroreductase PF00881.24 ORY51131.1 - 4e-11 43.2 0.0 5.6e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family IBR PF01485.21 ORY51133.1 - 0.097 12.9 2.2 0.2 11.9 2.2 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Lzipper-MIP1 PF14389.6 ORY51135.1 - 0.57 10.5 5.0 0.94 9.8 0.2 2.9 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF3450 PF11932.8 ORY51136.1 - 0.00077 18.8 1.2 0.001 18.4 1.0 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3450) Nsp1_C PF05064.13 ORY51136.1 - 0.00095 19.0 1.0 0.0011 18.8 1.0 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region ZapB PF06005.12 ORY51136.1 - 0.0011 19.4 4.4 0.0014 19.0 4.4 1.3 1 1 0 1 1 1 1 Cell division protein ZapB BLOC1_2 PF10046.9 ORY51136.1 - 0.0022 18.2 0.8 0.0029 17.9 0.8 1.2 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc29 PF17082.5 ORY51136.1 - 0.0029 17.5 0.9 0.0033 17.3 0.9 1.1 1 0 0 1 1 1 1 Spindle Pole Component 29 BST2 PF16716.5 ORY51136.1 - 0.0042 17.6 2.2 0.0053 17.3 2.2 1.2 1 0 0 1 1 1 1 Bone marrow stromal antigen 2 GAS PF13851.6 ORY51136.1 - 0.0057 16.0 2.8 0.0064 15.9 2.8 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding YabA PF06156.13 ORY51136.1 - 0.018 15.6 1.2 0.022 15.4 1.2 1.2 1 0 0 1 1 1 0 Initiation control protein YabA CCDC92 PF14916.6 ORY51136.1 - 0.019 14.7 3.5 0.034 13.9 3.3 1.6 1 1 0 1 1 1 0 Coiled-coil domain of unknown function Cluap1 PF10234.9 ORY51136.1 - 0.019 14.4 1.4 0.02 14.3 1.4 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Herpes_UL6 PF01763.16 ORY51136.1 - 0.019 13.5 1.5 0.02 13.5 1.5 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like HlyD_D23 PF16576.5 ORY51136.1 - 0.027 13.7 1.0 0.029 13.6 1.0 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion TMF_DNA_bd PF12329.8 ORY51136.1 - 0.034 14.1 1.1 0.034 14.1 1.1 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Rab_bind PF16704.5 ORY51136.1 - 0.034 14.2 0.3 2.8 8.1 0.1 2.3 1 1 1 2 2 2 0 Rab binding domain Sec34 PF04136.15 ORY51136.1 - 0.035 14.0 1.3 0.039 13.8 1.3 1.1 1 0 0 1 1 1 0 Sec34-like family APG6_N PF17675.1 ORY51136.1 - 0.046 14.3 2.7 0.062 13.8 2.7 1.3 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF948 PF06103.11 ORY51136.1 - 0.077 13.3 0.4 0.11 12.8 0.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Fib_alpha PF08702.10 ORY51136.1 - 0.13 12.5 2.9 0.52 10.5 2.8 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family XhlA PF10779.9 ORY51136.1 - 0.14 12.4 1.7 0.27 11.5 1.7 1.5 1 0 0 1 1 1 0 Haemolysin XhlA USP8_interact PF08941.10 ORY51136.1 - 0.15 11.9 1.9 0.18 11.6 1.9 1.1 1 0 0 1 1 1 0 USP8 interacting SlyX PF04102.12 ORY51136.1 - 0.27 11.9 4.6 2.1 9.0 4.6 2.1 1 1 0 1 1 1 0 SlyX DivIC PF04977.15 ORY51136.1 - 0.77 9.6 4.7 3.7 7.4 4.7 2.0 1 1 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 ORY51136.1 - 0.98 9.6 3.9 3.9 7.6 1.2 2.3 1 1 1 2 2 2 0 Basic region leucine zipper zf-RING_2 PF13639.6 ORY51227.1 - 1.2e-11 44.8 7.5 1.2e-11 44.8 7.5 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 ORY51227.1 - 5.4e-10 38.8 7.1 1.3e-09 37.7 7.1 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORY51227.1 - 3.1e-08 33.3 5.6 5.9e-08 32.4 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY51227.1 - 9e-08 32.3 6.7 2.3e-07 31.0 6.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 ORY51227.1 - 2.2e-07 30.6 4.7 5.3e-07 29.4 4.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORY51227.1 - 8.2e-06 25.8 3.5 2.6e-05 24.2 3.5 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 ORY51227.1 - 8.4e-06 25.7 4.0 1.6e-05 24.7 4.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY51227.1 - 6.1e-05 22.8 4.7 0.00013 21.7 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY51227.1 - 0.00021 21.1 5.8 0.00045 20.0 5.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 ORY51227.1 - 0.00096 19.1 5.0 0.0011 19.0 1.7 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 ORY51227.1 - 0.02 14.7 2.5 0.054 13.3 2.5 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 ORY51227.1 - 0.15 12.2 3.2 0.41 10.8 3.2 1.7 1 1 0 1 1 1 0 RING-variant domain zf-HC5HC2H_2 PF13832.6 ORY51227.1 - 0.16 12.1 3.1 0.36 11.0 3.1 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain PHD PF00628.29 ORY51227.1 - 0.31 11.0 5.0 0.63 10.0 5.0 1.6 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 ORY51227.1 - 0.51 10.6 6.6 7.4 6.8 6.6 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 ORY51227.1 - 0.62 10.4 5.6 1.6 9.1 5.6 1.8 1 1 0 1 1 1 0 RING-like domain Lipase_3 PF01764.25 ORY51228.1 - 7.1e-11 42.2 0.0 1.1e-08 35.1 0.0 2.5 2 0 0 2 2 2 2 Lipase (class 3) Lipase_3 PF01764.25 ORY51229.1 - 6.4e-30 103.9 0.0 9.5e-30 103.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 ORY51229.1 - 0.0071 15.9 0.0 0.0085 15.6 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Thioesterase PF00975.20 ORY51229.1 - 0.013 15.6 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 ORY51229.1 - 0.034 13.8 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF2974 PF11187.8 ORY51229.1 - 0.053 13.1 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) zf-RING_2 PF13639.6 ORY51230.1 - 1.2e-06 28.8 1.3 1.7e-06 28.2 1.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORY51230.1 - 1.5e-06 27.8 1.2 2.3e-06 27.3 1.2 1.2 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORY51230.1 - 3e-06 27.0 1.2 4.6e-06 26.4 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY51230.1 - 0.00018 21.5 0.9 0.00029 20.8 0.9 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY51230.1 - 0.00027 20.7 0.6 0.00046 20.0 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY51230.1 - 0.00069 19.5 1.1 0.00097 19.0 1.1 1.2 1 0 0 1 1 1 1 zinc-RING finger domain Zf_RING PF16744.5 ORY51230.1 - 0.00073 19.6 0.9 0.001 19.1 0.9 1.2 1 0 0 1 1 1 1 KIAA1045 RING finger PHD PF00628.29 ORY51230.1 - 0.013 15.3 2.1 0.019 14.9 2.1 1.2 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.11 ORY51230.1 - 0.021 15.1 2.6 0.03 14.6 2.6 1.2 1 0 0 1 1 1 0 RING-like domain SulA PF03846.14 ORY51230.1 - 0.054 13.4 0.0 0.056 13.4 0.0 1.1 1 0 0 1 1 1 0 Cell division inhibitor SulA zf-ANAPC11 PF12861.7 ORY51230.1 - 0.091 12.8 5.2 1.7 8.8 5.2 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 ORY51230.1 - 0.13 12.5 8.5 6.5 7.1 8.5 2.3 1 1 0 1 1 1 0 RING-H2 zinc finger domain ANF_receptor PF01094.28 ORY51232.1 - 4e-28 98.5 0.3 5.1e-28 98.2 0.3 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY51232.1 - 8.7e-06 25.6 0.4 1.2e-05 25.2 0.4 1.2 1 0 0 1 1 1 1 Periplasmic binding protein zf-RING_2 PF13639.6 ORY51233.1 - 1.4e-09 38.1 8.7 2.2e-09 37.5 8.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORY51233.1 - 1.3e-08 34.4 5.9 2.8e-08 33.3 5.9 1.6 1 0 0 1 1 1 1 RING-like zinc finger PA PF02225.22 ORY51233.1 - 5.8e-07 29.4 0.2 1.1e-06 28.6 0.2 1.5 1 0 0 1 1 1 1 PA domain zf-C3HC4 PF00097.25 ORY51233.1 - 1.3e-05 25.0 7.3 2.1e-05 24.3 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY51233.1 - 7.9e-05 22.9 8.3 0.00021 21.5 8.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORY51233.1 - 8.8e-05 22.3 8.3 0.00014 21.7 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY51233.1 - 0.00043 20.1 4.9 0.00067 19.5 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORY51233.1 - 0.0022 18.0 1.6 0.0056 16.7 1.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger MRI PF15325.6 ORY51233.1 - 0.0066 17.5 0.4 0.012 16.6 0.4 1.5 1 0 0 1 1 1 1 Modulator of retrovirus infection Prok-RING_4 PF14447.6 ORY51233.1 - 0.0085 15.9 6.9 0.016 15.1 6.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 ORY51233.1 - 0.015 15.3 5.7 0.023 14.6 5.7 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY51233.1 - 0.029 14.4 4.3 0.029 14.4 4.3 2.3 2 0 0 2 2 2 0 RING-type zinc-finger PHD PF00628.29 ORY51233.1 - 0.18 11.7 5.1 0.33 10.9 5.1 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 ORY51233.1 - 4.5 7.5 8.6 62 3.9 8.6 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain 7tm_3 PF00003.22 ORY51234.1 - 2e-16 60.5 22.0 2.9e-16 59.9 22.0 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Kelch_3 PF13415.6 ORY51236.1 - 4.5e-24 84.2 1.5 1.3e-05 25.3 0.0 6.4 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.6 ORY51236.1 - 7.4e-19 67.5 1.5 0.0092 16.0 0.0 5.5 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_1 PF01344.25 ORY51236.1 - 2.3e-17 62.3 0.2 0.00044 19.8 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 ORY51236.1 - 4.1e-16 58.2 3.5 0.00039 20.3 0.0 5.6 5 1 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 ORY51236.1 - 1.4e-15 56.9 0.0 0.042 14.2 0.0 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 ORY51236.1 - 7.6e-14 51.3 0.2 0.16 12.0 0.0 5.4 5 0 0 5 5 5 5 Kelch motif zf-MYND PF01753.18 ORY51236.1 - 6.9e-10 38.9 14.4 1.5e-09 37.8 14.4 1.6 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY51236.1 - 0.11 12.8 7.0 0.35 11.2 7.0 1.9 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PolC_DP2 PF03833.13 ORY51236.1 - 1.1 7.0 3.9 1.4 6.7 3.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 TPR_2 PF07719.17 ORY51237.1 - 0.012 15.6 0.1 0.029 14.5 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY51237.1 - 0.028 14.2 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY51237.1 - 0.094 12.8 0.5 1.2 9.4 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Lamp PF01299.17 ORY51237.1 - 0.16 11.8 0.4 0.38 10.6 0.1 1.7 1 1 1 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) FliG_N PF14842.6 ORY51239.1 - 0.12 13.0 0.1 0.28 11.7 0.1 1.5 1 1 1 2 2 2 0 FliG N-terminal domain Methyltransf_23 PF13489.6 ORY51240.1 - 8e-25 87.6 0.0 1.3e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY51240.1 - 4.3e-19 69.0 0.0 9.3e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY51240.1 - 4.5e-14 52.5 0.0 6.3e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY51240.1 - 6.4e-14 52.4 0.0 1.3e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY51240.1 - 3.6e-13 50.1 0.0 9.9e-13 48.7 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain CMAS PF02353.20 ORY51240.1 - 1.7e-09 37.4 0.0 3.4e-09 36.4 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 ORY51240.1 - 6.6e-05 22.4 0.0 0.0001 21.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.11 ORY51240.1 - 0.0014 17.6 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) DREV PF05219.12 ORY51240.1 - 0.0017 17.5 0.0 0.011 14.9 0.0 1.9 1 1 0 1 1 1 1 DREV methyltransferase Methyltransf_32 PF13679.6 ORY51240.1 - 0.0082 16.1 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 ORY51240.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain NodS PF05401.11 ORY51240.1 - 0.02 14.5 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) MetW PF07021.12 ORY51240.1 - 0.034 13.7 0.1 0.098 12.2 0.1 1.7 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW ADH_zinc_N PF00107.26 ORY51240.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_PK PF05891.12 ORY51240.1 - 0.17 11.4 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase WD40 PF00400.32 ORY51241.1 - 0.00026 21.7 0.1 0.0014 19.4 0.0 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 ORY51241.1 - 0.0056 15.7 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 ORY51241.1 - 0.01 16.1 0.0 3.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY51241.1 - 0.046 13.6 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Alk_phosphatase PF00245.20 ORY51242.1 - 2e-59 201.6 0.1 4.5e-59 200.5 0.1 1.6 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 ORY51242.1 - 4.4e-05 23.0 0.1 0.00077 18.9 0.0 2.3 2 0 0 2 2 2 1 Metalloenzyme superfamily Aminotran_3 PF00202.21 ORY51243.1 - 1e-89 301.1 0.0 9.4e-89 297.9 0.0 2.3 1 1 0 1 1 1 1 Aminotransferase class-III zf-RING_2 PF13639.6 ORY51244.1 - 2e-10 40.8 11.3 3.9e-10 39.9 11.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY51244.1 - 8.6e-08 31.9 9.8 1.6e-07 31.0 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY51244.1 - 1.8e-07 30.9 5.4 3.2e-07 30.1 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY51244.1 - 2e-07 30.6 5.5 2e-07 30.6 5.5 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 ORY51244.1 - 0.00092 19.5 14.2 0.0044 17.3 14.2 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain PA PF02225.22 ORY51244.1 - 0.0049 16.9 0.1 0.012 15.6 0.1 1.7 1 0 0 1 1 1 1 PA domain zf-RING_UBOX PF13445.6 ORY51244.1 - 0.0051 16.8 1.8 0.0051 16.8 1.8 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 ORY51244.1 - 0.0059 16.6 1.9 0.013 15.5 1.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 ORY51244.1 - 0.049 13.6 8.5 0.092 12.7 8.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY51244.1 - 0.055 13.3 8.2 0.098 12.5 8.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 ORY51244.1 - 0.078 13.3 4.3 0.14 12.5 4.3 1.4 1 0 0 1 1 1 0 RING-like domain Prok-RING_4 PF14447.6 ORY51244.1 - 0.16 11.9 6.1 0.33 10.8 6.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 GFO_IDH_MocA PF01408.22 ORY51246.1 - 5e-08 33.8 0.0 8.9e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold p450 PF00067.22 ORY51247.1 - 3.3e-49 167.9 0.1 4.2e-49 167.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 COG5 PF10392.9 ORY51247.1 - 0.059 13.5 0.3 0.13 12.4 0.3 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Glyco_transf_90 PF05686.12 ORY51248.1 - 0.018 14.0 0.1 0.03 13.2 0.1 1.4 1 1 0 1 1 1 0 Glycosyl transferase family 90 LysM PF01476.20 ORY51250.1 - 2.7e-12 46.5 0.0 0.0011 19.0 0.1 3.2 3 0 0 3 3 3 3 LysM domain BSMAP PF12280.8 ORY51251.1 - 0.26 11.5 3.6 0.13 12.5 1.5 1.5 2 0 0 2 2 2 0 Brain specific membrane anchored protein Lipase_3 PF01764.25 ORY51252.1 - 7.1e-06 25.9 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) RCDG1 PF15725.5 ORY51252.1 - 2.5 8.6 9.2 1.3 9.4 3.6 2.7 3 0 0 3 3 3 0 Renal cancer differentiation gene 1 protein ADK PF00406.22 ORY51253.1 - 4.4e-18 65.8 0.0 4.4e-15 56.1 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 ORY51253.1 - 9e-12 45.6 0.0 2.1e-11 44.4 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 ORY51253.1 - 2.5e-06 27.7 0.0 2.9e-05 24.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 ORY51253.1 - 1.2e-05 25.7 0.1 0.019 15.3 0.0 2.3 2 0 0 2 2 2 2 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 ORY51253.1 - 2.5e-05 24.9 0.1 0.0006 20.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ORY51253.1 - 0.038 13.3 0.6 0.22 10.7 0.0 2.0 1 1 1 2 2 2 0 Zeta toxin AAA_16 PF13191.6 ORY51253.1 - 0.044 14.2 0.0 0.088 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 ORY51253.1 - 0.049 12.8 0.0 0.093 11.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain UPF0302 PF08864.10 ORY51253.1 - 0.051 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 UPF0302 domain NACHT PF05729.12 ORY51253.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.18 ORY51253.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF4927 PF16279.5 ORY51253.1 - 0.15 13.1 0.0 0.29 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4927) AAA_5 PF07728.14 ORY51253.1 - 0.17 11.9 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ADK PF00406.22 ORY51254.1 - 1e-09 38.7 0.0 1.3e-09 38.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase Hydin_ADK PF17213.3 ORY51254.1 - 0.0025 18.1 0.0 0.0032 17.8 0.0 1.1 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain AAA_17 PF13207.6 ORY51254.1 - 0.0082 16.6 0.0 0.01 16.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain zf-CCHC PF00098.23 ORY51255.1 - 3.2e-05 23.8 3.6 5.5e-05 23.0 3.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 ORY51255.1 - 0.0076 16.1 0.8 0.019 14.8 0.8 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 ORY51255.1 - 1.6 8.6 3.8 2.9 7.8 3.8 1.4 1 0 0 1 1 1 0 Zinc knuckle Tektin PF03148.14 ORY51255.1 - 2 7.1 8.7 0.11 11.2 3.3 1.6 2 0 0 2 2 2 0 Tektin family Inhibitor_I71 PF12628.7 ORY51256.1 - 0.56 10.0 3.1 0.92 9.3 3.1 1.3 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor DUF4169 PF13770.6 ORY51256.1 - 2.3 8.5 11.2 0.13 12.6 4.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4169) ANF_receptor PF01094.28 ORY51257.1 - 7.3e-25 87.8 0.0 1e-24 87.3 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 ORY51257.1 - 6.6e-12 45.7 9.4 1.5e-11 44.5 9.4 1.6 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 ORY51257.1 - 6.6e-06 26.0 0.1 2.5e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Periplasmic binding protein ANF_receptor PF01094.28 ORY51258.1 - 6.4e-25 88.0 0.0 2.2e-24 86.2 0.0 1.8 2 1 0 2 2 2 1 Receptor family ligand binding region 7tm_3 PF00003.22 ORY51258.1 - 3.4e-12 46.6 27.5 5.9e-12 45.8 27.5 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 ORY51258.1 - 0.00025 20.8 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein TMEM65 PF10507.9 ORY51258.1 - 0.012 15.6 0.1 0.42 10.6 0.1 3.0 3 0 0 3 3 3 0 Transmembrane protein 65 Pullulanase_Ins PF18494.1 ORY51258.1 - 0.21 12.1 4.1 21 5.7 0.0 3.1 3 0 0 3 3 3 0 Pullulanase Ins domain DUF4064 PF13273.6 ORY51258.1 - 0.4 11.0 9.4 49 4.3 6.3 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF4064) DUF805 PF05656.14 ORY51258.1 - 1.9 8.9 8.6 12 6.4 5.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF805) Nab6_mRNP_bdg PF10567.9 ORY51260.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.1 1 0 0 1 1 1 0 RNA-recognition motif DDE_3 PF13358.6 ORY51261.1 - 1.9e-09 37.5 0.0 5e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease DXP_reductoisom PF02670.16 ORY51261.1 - 0.042 14.6 0.5 16 6.2 0.0 2.7 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase 7tm_3 PF00003.22 ORY51262.1 - 1.3e-18 67.7 21.4 2.1e-18 67.0 21.4 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR LapA_dom PF06305.11 ORY51262.1 - 1.6 8.6 6.6 0.36 10.7 1.2 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain ANF_receptor PF01094.28 ORY51263.1 - 4e-13 49.2 0.7 5.9e-11 42.1 0.2 2.1 2 0 0 2 2 2 2 Receptor family ligand binding region ECH_1 PF00378.20 ORY51264.1 - 8.7e-58 195.6 0.0 1e-57 195.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 ORY51264.1 - 4.5e-29 102.0 0.0 6.4e-28 98.2 0.0 1.9 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase TFIIA PF03153.13 ORY51265.1 - 0.18 11.8 25.6 0.01 15.9 18.8 1.9 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pannexin_like PF12534.8 ORY51265.1 - 2.9 6.9 8.8 0.034 13.2 0.8 1.7 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 Conotoxin PF02950.17 ORY51265.1 - 3.4 8.7 4.0 22 6.1 3.4 2.8 2 1 0 2 2 2 0 Conotoxin ANF_receptor PF01094.28 ORY51266.1 - 4.9e-15 55.5 0.0 6.5e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY51266.1 - 5.5e-07 29.6 0.0 7.1e-07 29.2 0.0 1.0 1 0 0 1 1 1 1 Periplasmic binding protein 7tm_3 PF00003.22 ORY51267.1 - 7.5e-10 38.9 13.1 7.5e-10 38.9 13.1 1.3 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Hist_deacetyl PF00850.19 ORY51268.1 - 5.6e-83 278.9 0.0 8.5e-83 278.3 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain ANF_receptor PF01094.28 ORY51269.1 - 1.6e-18 67.0 0.5 2e-18 66.7 0.5 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 ORY51269.1 - 8.4e-05 22.4 11.5 8.4e-05 22.4 11.5 1.8 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR CRPA PF05745.11 ORY51269.1 - 0.0058 16.7 5.2 0.015 15.3 5.2 1.7 1 0 0 1 1 1 1 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Sel1 PF08238.12 ORY51270.1 - 3.6e-15 56.0 13.8 1.4e-06 28.8 0.0 6.1 6 0 0 6 6 6 4 Sel1 repeat TPR_12 PF13424.6 ORY51270.1 - 0.057 13.7 7.1 0.92 9.8 0.0 4.2 4 2 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY51270.1 - 0.12 12.9 6.1 0.72 10.4 0.2 4.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY51270.1 - 0.49 11.1 8.8 4 8.2 0.1 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY51270.1 - 1.2 9.5 11.3 5.5 7.5 0.0 5.5 7 0 0 7 7 7 0 Tetratricopeptide repeat 7tm_3 PF00003.22 ORY51271.1 - 2.6e-17 63.4 23.5 3.3e-17 63.0 23.5 1.0 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR YjbT PF17089.5 ORY51271.1 - 0.15 12.1 0.1 8.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family NapE PF06796.11 ORY51271.1 - 8.5 6.0 11.1 0.24 11.0 3.2 2.6 2 1 0 2 2 2 0 Periplasmic nitrate reductase protein NapE ANF_receptor PF01094.28 ORY51272.1 - 2.8e-11 43.1 0.0 4.1e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY51272.1 - 0.00073 19.3 0.1 0.0018 18.0 0.0 1.5 2 0 0 2 2 2 1 Periplasmic binding protein Sec34 PF04136.15 ORY51273.1 - 4.1e-38 130.6 0.1 8.5e-37 126.3 0.1 2.4 2 0 0 2 2 2 1 Sec34-like family TLE_N PF03920.15 ORY51273.1 - 0.16 12.0 0.4 0.45 10.6 0.4 1.7 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain SSP160 PF06933.11 ORY51273.1 - 5.7 5.0 10.9 9.8 4.2 10.9 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sel1 PF08238.12 ORY51275.1 - 1.3e-26 92.5 7.3 4.7e-07 30.3 0.2 5.0 5 0 0 5 5 5 4 Sel1 repeat TPR_2 PF07719.17 ORY51276.1 - 0.0034 17.4 0.1 0.025 14.7 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY51276.1 - 0.0075 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat MCM3AP_GANP PF16769.5 ORY51276.1 - 2.2 6.4 14.9 3.4 5.8 14.9 1.2 1 0 0 1 1 1 0 MCM3AP domain of GANP DSPc PF00782.20 ORY51277.1 - 0.00015 21.6 0.1 0.00052 19.8 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY51277.1 - 0.0054 16.3 0.0 0.0064 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase 7tm_3 PF00003.22 ORY51278.1 - 6.6e-23 81.7 15.7 8.7e-23 81.3 15.7 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF2678 PF10856.8 ORY51278.1 - 0.056 13.4 5.1 0.23 11.4 0.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2678) ANF_receptor PF01094.28 ORY51279.1 - 0.0044 16.2 0.0 0.0065 15.6 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Tctex-1 PF03645.13 ORY51280.1 - 5.1e-14 52.4 0.5 3.5e-09 36.8 0.0 2.1 2 0 0 2 2 2 2 Tctex-1 family ATX_III PF08098.11 ORY51280.1 - 0.2 11.7 0.3 0.51 10.4 0.3 1.7 1 0 0 1 1 1 0 Anemonia sulcata toxin III family ANF_receptor PF01094.28 ORY51281.1 - 1.2e-26 93.6 0.0 1.8e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 ORY51281.1 - 2.1e-11 44.0 25.7 4.4e-11 43.0 25.7 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 ORY51281.1 - 1.1e-08 35.2 0.0 1.7e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Pet191_N PF10203.9 ORY51282.1 - 1.9e-18 66.5 3.9 2.1e-18 66.3 3.9 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Ysc84 PF04366.12 ORY51283.1 - 1.2e-39 135.0 0.6 1.6e-39 134.6 0.6 1.2 1 0 0 1 1 1 1 Las17-binding protein actin regulator PPR PF01535.20 ORY51284.1 - 1.3e-18 65.9 8.3 2.7e-06 27.2 0.0 7.5 7 1 0 7 7 7 4 PPR repeat PPR_2 PF13041.6 ORY51284.1 - 1.2e-17 63.8 12.5 2.2e-05 24.6 0.0 7.1 7 2 2 9 9 9 4 PPR repeat family PPR_1 PF12854.7 ORY51284.1 - 2.4e-16 59.1 0.5 6.3e-10 38.6 0.0 5.5 7 0 0 7 7 7 2 PPR repeat PPR_3 PF13812.6 ORY51284.1 - 7.2e-14 51.6 5.6 1.4e-05 25.1 0.1 5.6 6 1 0 6 6 6 2 Pentatricopeptide repeat domain PPR_long PF17177.4 ORY51284.1 - 9.9e-06 25.1 0.0 0.0095 15.3 0.0 3.4 1 1 2 3 3 3 1 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 ORY51284.1 - 0.0022 18.5 0.2 4 8.0 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY51284.1 - 0.0049 17.6 0.0 31 5.8 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat MRP-S27 PF10037.9 ORY51284.1 - 0.0072 15.2 1.9 0.44 9.4 0.0 3.0 2 2 2 4 4 4 1 Mitochondrial 28S ribosomal protein S27 ATP13 PF12921.7 ORY51284.1 - 0.0097 15.8 0.2 0.98 9.3 0.1 3.2 2 1 0 2 2 2 1 Mitochondrial ATPase expression DUF4878 PF12870.7 ORY51284.1 - 0.038 14.3 0.1 0.09 13.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) FRB_dom PF08771.11 ORY51284.1 - 0.086 13.3 0.2 0.44 11.0 0.2 2.2 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain Clathrin PF00637.20 ORY51284.1 - 0.31 10.9 3.2 9.4 6.1 0.0 4.2 6 0 0 6 6 6 0 Region in Clathrin and VPS TPR_8 PF13181.6 ORY51284.1 - 0.47 10.8 4.4 18 5.9 0.0 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat 7tm_3 PF00003.22 ORY51286.1 - 4.6e-27 95.3 25.5 1.1e-26 94.0 25.5 1.6 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 ORY51286.1 - 1.8e-26 93.1 0.1 3.3e-26 92.2 0.1 1.3 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY51286.1 - 9.6e-14 51.8 0.2 1.6e-13 51.0 0.2 1.3 1 0 0 1 1 1 1 Periplasmic binding protein DUF3169 PF11368.8 ORY51286.1 - 0.097 12.2 12.8 0.014 14.9 5.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) zf-RING_2 PF13639.6 ORY51290.1 - 9.8e-13 48.2 7.8 2.2e-12 47.1 7.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 ORY51290.1 - 1.2e-09 37.7 6.0 2.6e-09 36.7 6.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 ORY51290.1 - 3e-07 30.2 6.7 6.8e-07 29.0 6.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY51290.1 - 7.8e-07 28.9 3.9 1.8e-06 27.7 3.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY51290.1 - 1.7e-05 25.0 12.9 7.4e-05 22.9 12.9 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain PA PF02225.22 ORY51290.1 - 0.00015 21.7 0.0 0.00038 20.4 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.6 ORY51290.1 - 0.00027 20.9 3.2 0.00048 20.0 3.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY51290.1 - 0.00044 20.2 5.3 0.00067 19.6 3.4 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 ORY51290.1 - 0.0006 19.8 4.2 0.0012 18.8 4.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 ORY51290.1 - 0.00082 19.2 6.1 0.0014 18.4 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 ORY51290.1 - 0.015 15.6 4.5 0.03 14.6 4.5 1.6 1 0 0 1 1 1 0 RING-like domain Prok-RING_4 PF14447.6 ORY51290.1 - 0.02 14.7 7.6 0.069 13.0 7.7 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 ORY51290.1 - 0.057 13.5 5.7 0.18 11.9 5.7 2.0 1 1 0 1 1 1 0 Zinc-finger PHD PF00628.29 ORY51290.1 - 0.18 11.7 6.6 0.36 10.8 6.6 1.5 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 ORY51290.1 - 1.4 8.6 8.5 3.1 7.5 8.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 ORY51290.1 - 7.4 6.8 9.1 27 5.1 9.1 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain ANF_receptor PF01094.28 ORY51293.1 - 6e-16 58.5 1.1 1.3e-15 57.4 1.1 1.6 1 1 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY51293.1 - 0.0015 18.3 0.1 0.0023 17.7 0.1 1.3 1 0 0 1 1 1 1 Periplasmic binding protein DUF1198 PF06711.11 ORY51293.1 - 0.057 13.5 0.1 0.088 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) Pox_A32 PF04665.12 ORY51293.1 - 0.069 12.6 0.7 0.11 12.0 0.4 1.4 1 1 0 1 1 1 0 Poxvirus A32 protein ANF_receptor PF01094.28 ORY51294.1 - 5.5e-22 78.4 0.0 7.2e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 ORY51294.1 - 5.9e-07 29.4 10.1 1.2e-06 28.5 10.1 1.5 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 ORY51294.1 - 7.7e-05 22.5 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Y_Y_Y PF07495.13 ORY51294.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Y_Y_Y domain zf-RING_2 PF13639.6 ORY51295.1 - 6.7e-12 45.6 8.1 1.1e-11 44.9 8.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY51295.1 - 2.6e-08 33.5 7.3 4.5e-08 32.8 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY51295.1 - 3.2e-08 33.2 4.7 3.2e-08 33.2 4.7 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 ORY51295.1 - 1.4e-07 31.3 6.6 2.3e-07 30.5 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY51295.1 - 5.9e-07 29.7 6.4 1.4e-06 28.5 6.4 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORY51295.1 - 0.00021 21.3 3.8 0.0004 20.4 3.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 ORY51295.1 - 0.00023 21.1 3.4 0.00023 21.1 3.4 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORY51295.1 - 0.00045 20.0 5.3 0.00094 19.0 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 ORY51295.1 - 0.00045 20.2 0.4 0.00097 19.1 0.1 1.6 1 1 1 2 2 2 1 PA domain zf-RING_5 PF14634.6 ORY51295.1 - 0.00056 19.8 5.2 0.00092 19.1 5.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 ORY51295.1 - 0.004 16.9 4.7 0.01 15.6 4.7 1.6 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 ORY51295.1 - 0.0042 16.9 10.3 0.24 11.3 11.0 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 PHD PF00628.29 ORY51295.1 - 0.0083 16.0 6.3 0.015 15.2 6.3 1.4 1 0 0 1 1 1 1 PHD-finger C1_2 PF03107.16 ORY51295.1 - 0.037 14.4 2.3 0.052 13.9 1.0 1.9 2 0 0 2 2 2 0 C1 domain zf-HC5HC2H_2 PF13832.6 ORY51295.1 - 0.06 13.5 2.1 0.13 12.4 2.1 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain Zn_ribbon_17 PF17120.5 ORY51295.1 - 0.065 12.9 4.7 0.16 11.6 4.7 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 ORY51295.1 - 0.12 12.5 6.7 0.72 10.1 6.7 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-HC5HC2H PF13771.6 ORY51295.1 - 0.21 11.9 1.9 0.38 11.0 1.9 1.5 1 1 0 1 1 1 0 PHD-like zinc-binding domain DNA_RNApol_7kD PF03604.13 ORY51295.1 - 0.22 11.3 2.1 0.64 9.7 2.1 1.8 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit Prok-RING_1 PF14446.6 ORY51295.1 - 0.29 11.1 8.9 0.26 11.3 4.6 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.6 ORY51295.1 - 0.31 11.2 5.8 0.84 9.9 5.8 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zf_RING PF16744.5 ORY51295.1 - 0.31 11.2 3.4 0.61 10.2 3.4 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger C1_1 PF00130.22 ORY51295.1 - 0.59 10.1 4.1 0.31 11.0 1.2 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 ORY51295.1 - 0.95 9.6 5.3 1.9 8.7 0.5 2.5 1 1 1 2 2 2 0 Zinc ribbon domain zf-RING-like PF08746.11 ORY51295.1 - 5.1 7.5 6.4 18 5.7 6.3 2.0 1 1 1 2 2 2 0 RING-like domain DASH_Ask1 PF08655.10 ORY51297.1 - 0.0032 17.3 0.1 0.065 13.1 0.0 2.7 2 1 0 2 2 2 1 DASH complex subunit Ask1 cNMP_binding PF00027.29 ORY51298.1 - 3.4e-14 52.7 0.2 4.1e-09 36.4 0.0 3.9 4 0 0 4 4 4 2 Cyclic nucleotide-binding domain Cupin_3 PF05899.12 ORY51298.1 - 0.13 12.0 0.3 0.4 10.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Exo_endo_phos PF03372.23 ORY51299.1 - 2e-11 43.8 0.0 4.2e-11 42.8 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CLTH PF10607.9 ORY51300.1 - 1.4e-19 70.5 0.2 2.3e-19 69.7 0.2 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain ANF_receptor PF01094.28 ORY51301.1 - 1e-37 130.1 0.2 1.3e-37 129.7 0.2 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY51301.1 - 2.3e-08 34.1 0.2 3.2e-08 33.6 0.2 1.2 1 0 0 1 1 1 1 Periplasmic binding protein DUF4064 PF13273.6 ORY51301.1 - 0.0096 16.2 4.6 0.015 15.6 1.2 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF4064) 7tm_3 PF00003.22 ORY51301.1 - 0.016 14.9 3.8 0.016 14.9 3.8 2.2 2 0 0 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR ANF_receptor PF01094.28 ORY51302.1 - 3.8e-23 82.2 0.1 4.8e-23 81.8 0.1 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Lipase_GDSL_2 PF13472.6 ORY51303.1 - 4.7e-08 33.6 0.0 7.3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY51303.1 - 6.9e-05 22.9 0.0 0.00014 21.9 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase 7tm_3 PF00003.22 ORY51304.1 - 1.2e-06 28.5 7.9 2.1e-06 27.7 7.9 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR NnrS PF05940.12 ORY51304.1 - 0.022 14.2 0.9 0.033 13.6 0.9 1.2 1 0 0 1 1 1 0 NnrS protein ANF_receptor PF01094.28 ORY51305.1 - 0.0013 17.9 0.2 0.0026 16.9 0.2 1.5 1 1 0 1 1 1 1 Receptor family ligand binding region TPP_enzyme_M PF00205.22 ORY51305.1 - 0.035 13.9 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain HYLS1_C PF15311.6 ORY51306.1 - 3.1e-07 31.0 0.6 0.00086 20.0 0.1 2.3 2 0 0 2 2 2 2 Hydrolethalus syndrome protein 1 C-terminus ANF_receptor PF01094.28 ORY51307.1 - 1.9e-22 79.9 0.1 2.8e-22 79.3 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 ORY51307.1 - 8.5e-20 71.5 16.2 1.4e-19 70.8 16.2 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 ORY51307.1 - 8.9e-16 58.5 1.2 1.3e-15 57.9 1.2 1.2 1 0 0 1 1 1 1 Periplasmic binding protein RGS PF00615.19 ORY51308.1 - 2.5e-05 24.5 0.0 4.1e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 Regulator of G protein signaling domain Endotoxin_N PF03945.14 ORY51308.1 - 0.17 11.6 0.1 0.87 9.2 0.0 1.8 1 1 1 2 2 2 0 delta endotoxin, N-terminal domain zf-C2H2 PF00096.26 ORY51309.1 - 4.5e-07 30.0 10.0 2.4e-05 24.5 0.9 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.7 ORY51309.1 - 5.3e-05 23.5 3.6 0.0025 18.1 0.5 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 ORY51309.1 - 0.00013 22.5 6.0 0.00081 20.0 0.8 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY51309.1 - 0.0015 18.7 4.7 0.0081 16.4 0.0 2.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY51309.1 - 0.016 15.2 0.5 0.016 15.2 0.5 2.9 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORY51309.1 - 0.059 13.1 0.5 0.14 11.9 0.5 1.7 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 ORY51309.1 - 0.16 12.5 12.7 0.35 11.4 0.7 3.4 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2 PF00096.26 ORY51310.1 - 6.2e-07 29.5 15.1 8.6e-06 25.9 2.3 2.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY51310.1 - 5.9e-05 23.3 15.7 0.00043 20.6 1.8 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY51310.1 - 0.0001 22.8 13.7 0.00025 21.6 1.8 2.6 3 0 0 3 3 3 2 C2H2-type zinc finger Zf_RING PF16744.5 ORY51310.1 - 0.0033 17.5 3.3 0.37 10.9 0.1 2.4 1 1 1 2 2 2 2 KIAA1045 RING finger zf-C2H2_11 PF16622.5 ORY51310.1 - 0.028 14.2 1.0 0.062 13.1 1.0 1.5 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 ORY51310.1 - 0.029 14.7 4.9 0.046 14.0 0.1 2.7 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY51310.1 - 0.03 14.7 6.1 0.082 13.3 0.2 2.7 2 1 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 ORY51311.1 - 1.6e-10 40.8 9.1 4.4e-06 26.8 0.4 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY51311.1 - 1.7e-05 25.2 8.8 0.0022 18.7 0.5 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY51311.1 - 0.00038 20.7 1.0 0.0006 20.1 1.0 1.3 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 ORY51311.1 - 0.0042 17.5 11.3 0.07 13.6 1.4 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY51311.1 - 0.0073 16.3 0.7 0.0073 16.3 0.7 2.7 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 ORY51311.1 - 0.089 12.9 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 ORY51311.1 - 0.27 11.6 3.3 3 8.2 0.4 2.6 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 ORY51311.1 - 0.9 9.4 4.3 1.1 9.0 0.2 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type Amino_oxidase PF01593.24 ORY51312.1 - 1e-57 196.5 0.0 2.5e-57 195.2 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 ORY51312.1 - 1.2e-13 51.1 0.1 2.9e-13 49.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 ORY51312.1 - 0.00032 19.9 1.2 0.00054 19.1 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY51312.1 - 0.00052 19.3 0.0 0.00087 18.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY51312.1 - 0.001 18.8 1.5 0.002 17.7 1.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 ORY51312.1 - 0.0012 18.3 0.1 0.0018 17.7 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY51312.1 - 0.0013 17.5 0.2 0.0022 16.8 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 ORY51312.1 - 0.0023 17.1 0.3 0.004 16.3 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 ORY51312.1 - 0.007 16.9 0.1 0.035 14.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY51312.1 - 0.0086 15.4 1.7 0.0086 15.4 0.5 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY51312.1 - 0.0098 15.2 0.1 0.018 14.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 ORY51312.1 - 0.031 13.3 0.2 0.045 12.8 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 ORY51312.1 - 0.046 13.0 0.1 0.068 12.4 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Acetyltransf_1 PF00583.25 ORY51313.1 - 0.1 12.8 0.0 0.41 10.9 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Flavoprotein PF02441.19 ORY51314.1 - 1.8e-44 151.3 0.3 2e-44 151.1 0.3 1.0 1 0 0 1 1 1 1 Flavoprotein Arm PF00514.23 ORY51314.1 - 0.022 14.8 0.1 2 8.6 0.0 2.4 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat AKAP28 PF14469.6 ORY51315.1 - 3.9e-05 23.4 0.0 9.8e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 28 kDa A-kinase anchor UCR_14kD PF02271.16 ORY51315.1 - 0.07 13.1 2.1 0.076 13.0 0.3 2.0 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit TFIIA PF03153.13 ORY51315.1 - 1.3 8.9 17.8 1.9 8.4 17.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CTP_transf_1 PF01148.20 ORY51316.1 - 3.7e-35 122.0 25.2 3.1e-20 73.0 3.8 2.2 1 1 1 2 2 2 2 Cytidylyltransferase family Lactamase_B_6 PF16661.5 ORY51317.1 - 9.9e-23 80.6 0.0 1.8e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 ORY51317.1 - 4.3e-18 65.6 0.0 9e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 ORY51317.1 - 9.4e-18 63.9 0.0 1.9e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 ORY51317.1 - 2e-12 47.5 0.0 5.1e-12 46.2 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 ORY51317.1 - 2.7e-08 33.6 0.8 1.4e-07 31.2 0.1 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORY51317.1 - 5e-05 23.2 0.0 0.00014 21.8 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 ORY51317.1 - 0.0001 21.7 0.1 0.00096 18.4 0.0 2.3 2 1 0 2 2 2 1 Putative beta-lactamase-like family Spt4 PF06093.13 ORY51318.1 - 4.4e-29 100.4 0.2 6.2e-29 99.9 0.2 1.2 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger LPD26 PF18842.1 ORY51318.1 - 0.17 11.8 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 Large polyvalent protein associated domain 26 AAA_16 PF13191.6 ORY51319.1 - 0.00019 21.8 0.0 0.00026 21.4 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 ORY51319.1 - 0.00046 20.1 0.0 0.00084 19.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 ORY51319.1 - 0.0016 18.8 0.0 0.0024 18.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 ORY51319.1 - 0.0021 17.4 0.0 0.0029 17.0 0.0 1.1 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 ORY51319.1 - 0.0036 16.9 0.0 0.0043 16.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 ORY51319.1 - 0.0055 16.9 0.0 0.023 14.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 ORY51319.1 - 0.041 13.5 0.0 0.055 13.1 0.0 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 ORY51319.1 - 0.052 13.6 0.0 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Roc PF08477.13 ORY51319.1 - 0.075 13.3 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 ORY51319.1 - 0.079 12.7 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 ORY51319.1 - 0.079 13.4 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY51319.1 - 0.084 12.6 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 ORY51319.1 - 0.09 12.5 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 ORY51319.1 - 0.091 12.7 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 ORY51319.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 NTPase NB-ARC PF00931.22 ORY51319.1 - 0.13 11.4 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 ORY51319.1 - 0.13 12.7 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 ORY51319.1 - 0.16 11.7 0.1 0.26 11.0 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 ORY51319.1 - 0.18 11.2 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein DnaB_C PF03796.15 ORY51319.1 - 0.22 10.8 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain TPR_12 PF13424.6 ORY51320.1 - 9.3e-55 182.9 17.1 6.4e-14 52.0 0.1 5.8 3 2 3 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 ORY51320.1 - 1.5e-44 148.7 0.1 8e-07 28.7 0.0 8.1 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 ORY51320.1 - 2.1e-33 111.7 19.1 0.00013 21.8 0.2 8.3 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 ORY51320.1 - 1.5e-30 102.8 13.1 0.00025 20.9 0.1 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 ORY51320.1 - 4.2e-20 70.6 14.6 0.0015 18.3 0.1 7.9 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_7 PF13176.6 ORY51320.1 - 1.5e-19 68.5 9.9 0.00076 19.3 0.1 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORY51320.1 - 3.1e-11 43.1 0.3 0.15 13.0 0.0 6.5 8 1 0 8 8 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY51320.1 - 7.7e-07 29.1 3.7 0.47 10.9 0.0 6.8 7 1 0 7 7 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY51320.1 - 2e-06 27.4 0.6 0.0038 16.7 0.1 2.2 1 1 1 2 2 2 2 MalT-like TPR region TPR_19 PF14559.6 ORY51320.1 - 5e-06 26.9 3.0 1.5 9.4 0.0 5.2 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY51320.1 - 1.4e-05 25.6 2.3 0.83 10.4 0.0 5.5 6 1 0 6 6 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 ORY51320.1 - 3e-05 23.4 7.2 9 5.9 0.0 6.5 7 0 0 7 7 7 0 SHNi-TPR TPR_5 PF12688.7 ORY51320.1 - 0.00014 22.1 0.0 2.7 8.2 0.0 3.5 1 1 2 3 3 3 1 Tetratrico peptide repeat TPR_6 PF13174.6 ORY51320.1 - 0.00021 21.7 4.0 0.84 10.4 0.1 5.7 7 0 0 7 7 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY51320.1 - 0.0023 18.1 8.3 0.047 13.9 0.1 4.6 2 1 4 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 Sec16_C PF12931.7 ORY51320.1 - 0.0027 17.4 1.5 1.4 8.5 0.0 2.9 1 1 2 3 3 3 2 Sec23-binding domain of Sec16 DUF4404 PF14357.6 ORY51320.1 - 0.01 16.4 0.2 12 6.6 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4404) TPR_3 PF07720.12 ORY51320.1 - 0.022 14.7 6.4 0.052 13.6 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2225 PF09986.9 ORY51320.1 - 0.14 11.9 3.9 5.5 6.6 0.2 3.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) RPN7 PF10602.9 ORY51320.1 - 0.21 11.3 3.9 2.1 8.0 0.1 3.6 3 1 2 5 5 5 0 26S proteasome subunit RPN7 MIT PF04212.18 ORY51320.1 - 0.31 11.2 0.1 0.31 11.2 0.1 4.3 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.6 ORY51320.1 - 0.5 10.5 6.2 4.5 7.4 0.0 4.7 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat dsRBD2 PF17842.1 ORY51322.1 - 0.011 15.9 0.3 0.019 15.1 0.3 1.4 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 YjeF_N PF03853.15 ORY51323.1 - 1.5e-39 135.6 0.1 1.9e-39 135.3 0.1 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Acetyltransf_10 PF13673.7 ORY51324.1 - 8.1e-07 29.0 0.0 3.5e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY51324.1 - 0.00028 21.2 0.0 0.00049 20.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY51324.1 - 0.0074 16.5 0.0 0.011 16.0 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family LRR_8 PF13855.6 ORY51325.1 - 2.2e-33 113.8 87.5 6.4e-07 29.1 2.4 6.2 1 1 7 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 ORY51325.1 - 6.2e-20 71.0 38.9 4.8e-05 23.6 0.7 7.4 2 1 9 11 11 11 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY51325.1 - 1.2e-14 52.5 33.7 0.05 14.1 0.2 10.6 11 0 0 11 11 11 4 Leucine Rich Repeat LRR_6 PF13516.6 ORY51325.1 - 5.5e-06 26.0 42.2 0.092 12.8 0.1 9.6 10 0 0 10 10 10 4 Leucine Rich repeat LRR_9 PF14580.6 ORY51325.1 - 2.9 7.4 6.8 5.8 6.4 0.1 2.9 1 1 1 3 3 3 0 Leucine-rich repeat La PF05383.17 ORY51326.1 - 0.004 17.2 0.0 0.014 15.4 0.0 2.0 1 0 0 1 1 1 1 La domain GST_N PF02798.20 ORY51327.1 - 1.9e-15 56.9 0.1 6.4e-15 55.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY51327.1 - 5.5e-12 45.9 0.1 1.1e-11 45.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY51327.1 - 1.1e-08 35.2 0.1 2.7e-08 34.0 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY51327.1 - 8.8e-06 25.9 0.0 1.5e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY51327.1 - 1.7e-05 24.9 0.1 3e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY51327.1 - 2.3e-05 24.3 0.0 4.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 ORY51327.1 - 0.051 14.3 0.0 0.12 13.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Methyltransf_31 PF13847.6 ORY51328.1 - 8.9e-05 22.3 0.0 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY51328.1 - 0.018 15.8 0.0 0.03 15.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PilO PF04350.13 ORY51329.1 - 0.0035 17.5 0.0 0.78 9.9 0.0 2.1 2 0 0 2 2 2 2 Pilus assembly protein, PilO Asp PF00026.23 ORY51330.1 - 3.6e-63 213.9 1.2 5e-63 213.4 1.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY51330.1 - 1.7e-09 38.2 2.3 1.1e-07 32.2 0.4 2.2 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY51330.1 - 0.0099 15.7 0.0 0.031 14.0 0.0 1.7 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Aldo_ket_red PF00248.21 ORY51331.1 - 1e-46 159.5 0.1 1.7e-44 152.2 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 ORY51332.1 - 4.7e-42 144.2 0.3 9.3e-40 136.6 0.3 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 ORY51333.1 - 6.3e-44 150.3 0.0 5.3e-35 121.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Voldacs PF03517.13 ORY51334.1 - 1.7e-21 76.8 0.9 1.7e-21 76.8 0.9 1.6 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling DUF3839 PF12943.7 ORY51334.1 - 0.087 12.3 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3839) MBF1 PF08523.10 ORY51335.1 - 1.5e-16 60.6 2.0 1.5e-16 60.6 2.0 2.2 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 ORY51335.1 - 6.3e-11 42.2 0.3 1e-10 41.5 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 ORY51335.1 - 0.00021 21.6 0.0 0.0011 19.3 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 ORY51335.1 - 0.045 13.8 0.1 0.073 13.1 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_26 PF13443.6 ORY51335.1 - 0.1 13.0 0.0 0.17 12.4 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Metallophos PF00149.28 ORY51336.1 - 1.6e-32 113.7 0.1 2.4e-32 113.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 ORY51336.1 - 1.5e-27 95.7 1.5 2.9e-27 94.8 0.3 2.1 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_2 PF07719.17 ORY51336.1 - 9.9e-16 56.5 5.5 0.00012 21.9 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORY51336.1 - 3.9e-15 54.9 4.9 2.7e-05 23.8 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORY51336.1 - 1.1e-14 53.8 6.5 1.5e-07 31.0 1.5 3.4 2 1 1 3 3 3 3 TPR repeat TPR_14 PF13428.6 ORY51336.1 - 5.8e-10 39.2 1.0 0.0036 18.0 0.0 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY51336.1 - 8.3e-09 35.0 2.5 0.029 14.6 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 ORY51336.1 - 3.4e-08 33.5 0.0 0.00063 19.8 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY51336.1 - 2.8e-07 31.1 2.6 0.018 15.7 2.3 2.7 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY51336.1 - 2.5e-06 27.9 2.5 0.015 15.8 0.1 2.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY51336.1 - 0.00036 20.7 0.2 2.2 8.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY51336.1 - 0.0021 18.3 2.3 5.9 7.3 1.7 3.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY51336.1 - 0.0099 16.5 0.3 3.2 8.6 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 ORY51336.1 - 0.013 15.5 0.0 4.7 7.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY51336.1 - 0.051 13.7 0.3 0.42 10.7 0.0 2.5 2 1 1 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 ORY51336.1 - 0.11 12.4 2.2 21 5.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 ORY51336.1 - 0.38 11.1 3.4 1.2 9.5 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 ORY51336.1 - 0.62 9.6 2.3 7.2 6.2 0.0 3.3 4 0 0 4 4 4 0 SHNi-TPR MIT PF04212.18 ORY51336.1 - 0.71 10.0 5.1 0.6 10.2 1.8 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Transp_cyt_pur PF02133.15 ORY51337.1 - 2.3e-33 115.6 31.3 2.9e-33 115.3 31.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DNA_alkylation PF08713.11 ORY51338.1 - 5.9e-20 71.9 0.0 2.3e-18 66.7 0.0 2.7 1 1 0 1 1 1 1 DNA alkylation repair enzyme Acetyltransf_1 PF00583.25 ORY51338.1 - 3.7e-08 33.6 0.0 1e-07 32.2 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY51338.1 - 4.4e-05 23.8 0.0 9.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY51338.1 - 0.00052 19.9 0.0 0.0017 18.3 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 ORY51338.1 - 0.0022 17.9 0.0 0.0047 16.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CTU2 PF10288.9 ORY51339.1 - 2.3e-16 60.0 0.0 4.9e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 ORY51339.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 PP-loop family RabGAP-TBC PF00566.18 ORY51340.1 - 2.7e-34 118.7 4.6 1.2e-32 113.4 4.6 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain UPF0147 PF03685.13 ORY51340.1 - 0.065 13.3 0.0 0.56 10.3 0.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0147) DUF4083 PF13314.6 ORY51340.1 - 0.16 11.9 1.3 0.52 10.3 1.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) EFTUD2 PF16004.5 ORY51341.1 - 0.00063 20.3 1.8 0.00063 20.3 1.8 2.4 2 0 0 2 2 2 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus KfrA_N PF11740.8 ORY51341.1 - 1.1 9.9 22.7 1.7 9.4 6.1 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term Forkhead PF00250.18 ORY51342.1 - 0.018 15.3 0.1 2.6 8.4 0.0 2.9 3 0 0 3 3 3 0 Forkhead domain ANKH PF07260.11 ORY51342.1 - 0.083 12.1 0.0 0.16 11.1 0.0 1.4 2 0 0 2 2 2 0 Progressive ankylosis protein (ANKH) DUF3419 PF11899.8 ORY51344.1 - 6e-41 140.9 0.0 6.5e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) DUF2202 PF09968.9 ORY51344.1 - 0.12 12.3 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) DUF3419 PF11899.8 ORY51345.1 - 4.1e-76 256.7 0.0 6.3e-76 256.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_25 PF13649.6 ORY51345.1 - 1.1e-08 35.7 0.0 2.4e-07 31.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY51345.1 - 1.3e-06 29.0 0.0 2.1e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY51345.1 - 1.5e-06 28.1 0.0 2.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY51345.1 - 6.2e-06 26.1 0.0 2.7e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY51345.1 - 1.2e-05 25.9 0.0 5.8e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY51345.1 - 2.3e-05 23.8 0.0 4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 ORY51345.1 - 0.0041 16.4 0.0 0.0071 15.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain PCMT PF01135.19 ORY51345.1 - 0.0058 16.4 0.0 0.018 14.8 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 ORY51345.1 - 0.098 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Ank_4 PF13637.6 ORY51346.1 - 9.8e-18 64.3 0.6 8.4e-10 39.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY51346.1 - 3.3e-16 59.1 0.5 4.3e-09 36.5 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY51346.1 - 6.7e-16 58.7 0.5 9.7e-16 58.1 0.5 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY51346.1 - 9.4e-14 51.2 3.1 3.7e-08 33.4 0.1 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 ORY51346.1 - 9.2e-12 44.1 0.4 9.6e-07 28.7 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat DUF1843 PF08898.10 ORY51346.1 - 0.038 14.5 0.0 9.3 6.8 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Beta_elim_lyase PF01212.21 ORY51347.1 - 9.1e-78 261.5 0.0 1.1e-77 261.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 ORY51347.1 - 3.6e-06 26.4 0.0 5.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 ORY51347.1 - 0.00042 19.7 0.1 0.0041 16.5 0.1 2.3 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 ORY51347.1 - 0.0032 16.5 0.0 0.0061 15.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ORY51347.1 - 0.027 13.0 0.0 0.046 12.2 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme LRR_4 PF12799.7 ORY51348.1 - 8.6e-08 32.4 3.5 0.0025 18.2 0.0 4.9 4 1 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY51348.1 - 4.3e-05 23.2 3.0 20 5.5 0.0 6.0 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 ORY51348.1 - 0.00028 21.0 3.7 3.6 8.5 0.0 6.0 6 1 0 6 6 6 1 Leucine Rich Repeat LRR_8 PF13855.6 ORY51348.1 - 0.091 12.5 7.6 0.31 10.8 0.5 4.7 6 1 1 7 7 7 0 Leucine rich repeat SDA1 PF05285.12 ORY51350.1 - 0.0012 18.4 16.7 0.0012 18.4 16.7 1.1 1 0 0 1 1 1 1 SDA1 DARPP-32 PF05395.12 ORY51350.1 - 0.0069 16.6 6.2 0.0096 16.2 6.2 1.2 1 0 0 1 1 1 1 Protein phosphatase inhibitor 1/DARPP-32 CNDH2_C PF16858.5 ORY51350.1 - 0.11 12.3 6.2 0.11 12.4 6.2 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Nop14 PF04147.12 ORY51350.1 - 0.24 9.6 21.5 0.26 9.5 21.5 1.1 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.14 ORY51350.1 - 0.38 10.5 14.5 0.5 10.1 14.5 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PPP4R2 PF09184.11 ORY51350.1 - 0.48 10.0 14.5 0.53 9.8 14.5 1.3 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.10 ORY51350.1 - 0.7 9.2 18.4 0.82 8.9 18.4 1.2 1 0 0 1 1 1 0 BUD22 YqfQ PF14181.6 ORY51350.1 - 0.79 9.9 2.2 1.2 9.3 2.2 1.3 1 0 0 1 1 1 0 YqfQ-like protein DUF2457 PF10446.9 ORY51350.1 - 1.4 8.0 34.0 1.7 7.7 34.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Vfa1 PF08432.10 ORY51350.1 - 1.8 8.9 6.9 2.1 8.6 6.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CobT PF06213.12 ORY51350.1 - 3.5 6.9 21.4 4.8 6.5 21.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2076 PF09849.9 ORY51350.1 - 4 7.4 12.5 5 7.1 12.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TFIIA PF03153.13 ORY51350.1 - 4.8 7.1 21.5 4.7 7.1 21.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FYDLN_acid PF09538.10 ORY51350.1 - 6.1 7.6 24.8 12 6.7 24.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) SURF2 PF05477.11 ORY51350.1 - 6.6 6.4 9.4 8.8 5.9 9.4 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) RRN3 PF05327.11 ORY51350.1 - 6.7 5.1 19.5 7.8 4.9 19.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 ORY51350.1 - 8.6 4.5 20.6 11 4.1 20.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 ORY51350.1 - 8.9 4.3 36.7 11 3.9 36.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi zf-RING_2 PF13639.6 ORY51352.1 - 6e-13 48.9 5.9 6e-13 48.9 5.9 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 ORY51352.1 - 1.2e-09 37.9 4.2 1.2e-09 37.9 4.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY51352.1 - 1.6e-09 37.6 0.4 1.6e-09 37.6 0.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 ORY51352.1 - 5e-08 32.5 5.5 5e-08 32.5 5.5 2.6 3 1 1 4 4 3 1 RING-like zinc finger zf-rbx1 PF12678.7 ORY51352.1 - 1.2e-07 31.9 10.0 1.2e-06 28.6 10.0 2.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 ORY51352.1 - 1.3e-07 31.3 9.0 2.4e-07 30.5 6.6 2.6 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 ORY51352.1 - 1.1e-05 25.3 3.7 5.5e-05 23.1 3.7 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 ORY51352.1 - 3.4e-05 23.7 5.4 3.4e-05 23.7 5.4 2.1 2 1 0 2 2 2 1 zinc-RING finger domain RINGv PF12906.7 ORY51352.1 - 6.1e-05 23.1 4.8 0.00014 21.9 4.8 1.6 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 ORY51352.1 - 0.0024 18.0 9.4 0.021 15.0 9.4 2.3 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 ORY51352.1 - 0.0046 17.1 11.6 0.018 15.2 6.7 3.0 1 1 2 3 3 3 1 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 ORY51352.1 - 0.0074 15.9 6.1 0.0074 15.9 6.1 1.9 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type PHD PF00628.29 ORY51352.1 - 0.0087 15.9 7.3 0.022 14.7 7.3 1.7 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 ORY51352.1 - 0.0091 15.9 2.0 0.0091 15.9 2.0 2.2 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Baculo_RING PF05883.11 ORY51352.1 - 0.0099 15.9 0.7 0.014 15.4 0.7 1.3 1 0 0 1 1 1 1 Baculovirus U-box/Ring-like domain Prok-RING_1 PF14446.6 ORY51352.1 - 0.019 14.9 1.0 0.019 14.9 1.0 2.4 3 0 0 3 3 2 0 Prokaryotic RING finger family 1 zf-Nse PF11789.8 ORY51352.1 - 0.029 14.2 4.0 0.061 13.1 4.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 ORY51352.1 - 0.14 11.9 8.5 0.19 11.6 5.8 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Rtf2 PF04641.12 ORY51352.1 - 0.21 10.9 2.4 0.23 10.8 2.4 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger TPR_14 PF13428.6 ORY51353.1 - 4.6e-12 45.7 0.1 0.74 10.8 0.0 7.1 4 3 4 8 8 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY51353.1 - 3e-11 42.5 0.5 0.65 10.3 0.0 8.2 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY51353.1 - 1.4e-09 37.4 0.0 0.21 11.5 0.0 7.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY51353.1 - 2.7e-09 37.4 0.6 1.1 9.8 0.1 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 ORY51353.1 - 3.9e-09 36.1 0.9 0.073 12.8 0.0 5.4 6 0 0 6 6 6 2 TPR repeat TPR_8 PF13181.6 ORY51353.1 - 1.3e-07 31.3 9.4 0.27 11.6 0.0 8.6 9 1 1 10 10 10 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY51353.1 - 1.4e-06 28.2 0.0 1.4 9.5 0.0 6.9 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_12 PF13424.6 ORY51353.1 - 1.7e-06 28.2 0.4 0.98 9.8 0.1 5.4 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY51353.1 - 1.2e-05 25.9 0.0 0.57 10.9 0.0 4.1 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 ORY51353.1 - 0.00025 21.1 0.0 1.4 9.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Coatomer_E PF04733.14 ORY51353.1 - 0.0022 17.4 0.4 2 7.7 0.0 2.6 2 1 0 2 2 2 2 Coatomer epsilon subunit ANAPC3 PF12895.7 ORY51353.1 - 0.0028 17.8 6.5 0.35 11.1 0.2 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 ORY51353.1 - 0.0032 17.4 0.0 2.7 8.2 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 ORY51353.1 - 0.011 15.0 1.1 6.3 5.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat C2 PF00168.30 ORY51353.1 - 0.034 14.4 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 C2 domain PAP2 PF01569.21 ORY51354.1 - 3.2e-18 65.8 7.9 3.2e-18 65.8 7.9 3.5 4 0 0 4 4 4 1 PAP2 superfamily Pyridoxal_deC PF00282.19 ORY51356.1 - 4e-41 141.0 0.0 6.1e-41 140.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 ORY51356.1 - 6.6e-11 41.8 0.3 2.1e-09 36.8 0.0 2.6 1 1 2 3 3 3 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 ORY51356.1 - 3.7e-08 33.0 0.0 1.4e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.20 ORY51356.1 - 0.0095 14.7 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain SepSecS PF05889.13 ORY51356.1 - 0.018 13.8 0.0 0.029 13.1 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_1_2 PF00155.21 ORY51356.1 - 0.034 13.3 0.2 0.16 11.1 0.0 2.0 2 1 0 2 2 2 0 Aminotransferase class I and II CENP-X PF09415.10 ORY51358.1 - 1.1e-16 60.9 0.0 1.2e-16 60.8 0.0 1.0 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CSN8_PSD8_EIF3K PF10075.9 ORY51359.1 - 3e-07 30.5 0.0 0.013 15.5 0.0 2.2 2 0 0 2 2 2 2 CSN8/PSMD8/EIF3K family DUF932 PF06067.11 ORY51359.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF932) Glycos_transf_3 PF00591.21 ORY51360.1 - 4.5e-89 298.4 0.0 5.2e-89 298.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain DUF3572 PF12096.8 ORY51360.1 - 0.0057 16.8 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3572) Ribosomal_S27 PF01599.19 ORY51360.1 - 0.092 12.9 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S27a zf-MYND PF01753.18 ORY51361.1 - 4.2e-11 42.8 12.2 6.7e-11 42.1 12.2 1.3 1 0 0 1 1 1 1 MYND finger DUF2256 PF10013.9 ORY51361.1 - 0.031 14.4 5.3 0.08 13.1 5.3 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C6H2 PF15801.5 ORY51361.1 - 0.26 11.6 8.9 0.52 10.7 8.9 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Dpy-30 PF05186.13 ORY51362.1 - 0.0022 17.6 2.2 0.015 15.0 0.4 2.4 2 0 0 2 2 2 1 Dpy-30 motif MT PF12777.7 ORY51362.1 - 0.0026 16.8 0.0 0.0052 15.9 0.0 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor HBB PF06777.11 ORY51362.1 - 0.07 12.8 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Helical and beta-bridge domain PRF PF06875.11 ORY51362.1 - 2.5 7.5 5.7 1 8.8 0.3 2.7 3 0 0 3 3 3 0 Plethodontid receptivity factor PRF PPP1R32 PF15691.5 ORY51363.1 - 1.7e-09 37.3 0.0 6.8e-08 32.0 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 1 regulatory subunit 32 TRAF_BIRC3_bd PF16673.5 ORY51364.1 - 0.0084 15.9 0.4 0.015 15.1 0.4 1.4 1 0 0 1 1 1 1 TNF receptor-associated factor BIRC3 binding domain Torus PF16131.5 ORY51365.1 - 0.0031 18.2 2.4 0.0031 18.2 2.4 2.3 2 0 0 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 ORY51365.1 - 0.011 15.7 5.6 0.038 14.1 5.6 2.0 1 0 0 1 1 1 0 Zinc finger domain zf-CCHC_3 PF13917.6 ORY51365.1 - 0.023 14.7 8.3 0.42 10.6 0.8 2.8 2 0 0 2 2 2 0 Zinc knuckle OpuAC PF04069.12 ORY51366.1 - 0.00093 18.8 0.1 0.3 10.6 0.0 2.5 2 1 0 2 2 2 2 Substrate binding domain of ABC-type glycine betaine transport system Caps_synth_GfcC PF06251.11 ORY51367.1 - 0.081 12.5 0.2 0.13 11.9 0.2 1.2 1 0 0 1 1 1 0 Capsule biosynthesis GfcC Insulin_TMD PF17870.1 ORY51367.1 - 7.2 6.8 9.8 1.3 9.1 0.3 3.3 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment La PF05383.17 ORY51368.1 - 2.9e-15 56.0 0.0 8.2e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 La domain TFIIA PF03153.13 ORY51368.1 - 7.1 6.5 31.9 0.19 11.7 7.7 2.6 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 ORY51368.1 - 8.1 6.2 10.5 1.4 8.7 1.7 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 RRP7 PF12923.7 ORY51369.1 - 2.3e-34 118.1 13.7 3.2e-34 117.6 13.7 1.2 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 ORY51369.1 - 1.3e-08 34.9 0.0 4.4e-08 33.1 0.0 1.9 2 1 0 2 2 2 1 Rrp7 RRM-like N-terminal domain RRM_1 PF00076.22 ORY51369.1 - 1.2e-06 28.3 0.0 4.1e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 ORY51369.1 - 1.9 8.7 0.0 1.9 8.7 0.0 2.6 2 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF3668 PF12416.8 ORY51370.1 - 3.1e-19 69.7 0.0 1.6e-18 67.3 0.0 2.1 1 1 0 1 1 1 1 Cep120 protein C2 PF00168.30 ORY51370.1 - 5.5e-05 23.4 0.0 0.00096 19.4 0.0 2.9 3 0 0 3 3 3 1 C2 domain Exonuc_VII_L PF02601.15 ORY51370.1 - 0.071 12.7 16.6 0.6 9.6 2.2 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit AMPK1_CBM PF16561.5 ORY51371.1 - 2.7e-29 101.2 0.2 5.1e-29 100.3 0.2 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 ORY51371.1 - 6.3e-26 90.5 1.7 6.3e-26 90.5 1.7 1.8 1 1 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM53 PF16760.5 ORY51371.1 - 0.12 13.0 0.1 0.23 12.1 0.1 1.5 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) DUF4795 PF16043.5 ORY51373.1 - 0.083 12.5 0.6 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) AJAP1_PANP_C PF15298.6 ORY51373.1 - 0.34 11.1 15.2 0.45 10.7 15.2 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Plavaka PF18759.1 ORY51374.1 - 4.9e-43 147.6 0.0 6.9e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Plavaka transposase NifW PF03206.14 ORY51374.1 - 0.058 13.9 0.2 0.16 12.5 0.2 1.7 1 0 0 1 1 1 0 Nitrogen fixation protein NifW OTU PF02338.19 ORY51375.1 - 0.00024 21.6 0.0 0.00037 21.0 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease DUF3752 PF12572.8 ORY51376.1 - 1.1e-21 77.9 5.5 3.6e-21 76.3 5.5 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) LAMTOR PF15454.6 ORY51377.1 - 8.2e-11 42.4 0.3 1.9e-10 41.2 0.2 1.7 1 1 1 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Erf4 PF10256.9 ORY51377.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family MxiM PF11441.8 ORY51378.1 - 0.39 11.0 2.2 1.2 9.4 1.6 2.1 2 0 0 2 2 2 0 Pilot protein MxiM MGC-24 PF05283.11 ORY51378.1 - 1.9 8.9 12.7 4.2 7.8 12.7 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SET PF00856.28 ORY51379.1 - 1e-17 65.1 0.0 1.6e-17 64.4 0.0 1.3 1 1 0 1 1 1 1 SET domain DPBB_1 PF03330.18 ORY51381.1 - 7e-07 29.4 0.2 1.8e-06 28.1 0.2 1.7 1 1 0 1 1 1 1 Lytic transglycolase TCRP1 PF14944.6 ORY51381.1 - 0.026 14.5 0.1 0.033 14.2 0.1 1.1 1 0 0 1 1 1 0 Tongue Cancer Chemotherapy Resistant Protein 1 MT-A70 PF05063.14 ORY51382.1 - 2.1e-57 193.8 0.0 2.8e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 MT-A70 GFO_IDH_MocA PF01408.22 ORY51383.1 - 3e-23 82.9 0.1 5.2e-23 82.1 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 ORY51383.1 - 0.00027 21.5 0.1 0.0011 19.5 0.0 2.1 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent UPF0449 PF15136.6 ORY51383.1 - 0.15 12.5 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 PEP_mutase PF13714.6 ORY51384.1 - 3.1e-62 210.2 1.0 3.5e-62 210.0 1.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase RAG2 PF03089.14 ORY51385.1 - 0.048 12.6 0.2 0.39 9.7 0.1 2.1 2 0 0 2 2 2 0 Recombination activating protein 2 DUF3915 PF13054.6 ORY51385.1 - 0.13 12.2 0.6 0.5 10.3 0.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Ras PF00071.22 ORY51386.1 - 4.6e-40 136.9 0.0 5.4e-40 136.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 ORY51386.1 - 1.4e-13 51.1 0.0 1.9e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 ORY51386.1 - 0.012 15.0 0.0 0.022 14.2 0.0 1.5 1 1 0 1 1 1 0 ADP-ribosylation factor family Cullin_binding PF03556.15 ORY51387.1 - 3.2e-28 98.6 0.3 5.6e-28 97.8 0.3 1.4 1 0 0 1 1 1 1 Cullin binding LCM PF04072.14 ORY51387.1 - 0.002 18.1 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF1835 PF08874.10 ORY51387.1 - 0.0088 16.2 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1835) Nup160 PF11715.8 ORY51388.1 - 2e-05 23.5 0.0 3.8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Flavokinase PF01687.17 ORY51389.1 - 0.32 11.3 1.6 9 6.6 0.2 2.3 2 0 0 2 2 2 0 Riboflavin kinase DUF1744 PF08490.12 ORY51390.1 - 6.6e-133 443.2 3.8 1.1e-132 442.4 3.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 ORY51390.1 - 8.3e-77 258.6 1.7 1.8e-76 257.5 1.7 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 ORY51390.1 - 1.2e-14 53.9 3.6 1.5e-13 50.2 2.1 3.3 3 1 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 ORY51390.1 - 5.1e-09 36.1 0.5 1.8e-08 34.3 0.5 1.9 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 ORY51390.1 - 1.5e-05 25.1 0.1 8e-05 22.7 0.1 2.3 1 0 0 1 1 1 1 RNase_H superfamily PBP1_TM PF14812.6 ORY51390.1 - 2.9 8.3 6.7 12 6.4 6.7 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ATP-synt_J PF04911.12 ORY51391.1 - 0.033 13.8 1.3 0.033 13.8 1.3 3.4 3 0 0 3 3 3 0 ATP synthase j chain IBV_3A PF03617.13 ORY51391.1 - 0.033 14.2 2.6 0.07 13.1 0.3 2.5 2 1 0 2 2 2 0 IBV 3A protein p53-inducible11 PF14936.6 ORY51391.1 - 0.75 9.8 8.7 0.56 10.2 6.6 1.7 1 1 0 1 1 1 0 Tumour protein p53-inducible protein 11 Phage_holin_3_6 PF07332.11 ORY51391.1 - 1.3 9.1 0.0 1.3 9.1 0.0 2.6 2 1 1 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF2855 PF11017.8 ORY51392.1 - 1.7e-75 254.9 0.2 2e-75 254.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) DUF2855 PF11017.8 ORY51393.1 - 2.3e-73 247.9 0.1 2.6e-73 247.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) ELFV_dehydrog PF00208.21 ORY51395.1 - 4.7e-60 203.3 0.0 7.3e-60 202.7 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 ORY51395.1 - 3.5e-24 84.5 0.0 1.1e-16 59.7 0.0 2.3 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase Pribosyl_synth PF14572.6 ORY51396.1 - 1.2e-41 142.8 3.7 2.4e-37 128.8 1.8 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 ORY51396.1 - 5.9e-36 122.9 0.0 3.1e-35 120.6 0.0 2.1 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 ORY51396.1 - 4.2e-14 52.4 0.4 8.7e-14 51.3 0.4 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPF0181 PF03701.14 ORY51396.1 - 0.16 11.6 1.0 0.45 10.2 0.5 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) Nucleoporin2 PF04096.14 ORY51397.1 - 1.2e-26 93.6 0.0 2.3e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase UQ_con PF00179.26 ORY51398.1 - 4.4e-43 146.3 0.2 5.8e-42 142.7 0.0 2.0 1 1 1 2 2 2 1 Ubiquitin-conjugating enzyme RWD PF05773.22 ORY51398.1 - 0.11 12.8 0.5 0.26 11.6 0.4 1.8 1 1 0 1 1 1 0 RWD domain DUF4436 PF14494.6 ORY51399.1 - 2.1e-29 102.6 1.8 3.2e-29 102.0 1.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) Sigma_reg_N PF13800.6 ORY51399.1 - 4.9 7.5 6.4 11 6.4 0.0 3.1 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Rad51 PF08423.11 ORY51400.1 - 5.8e-25 88.0 1.2 8.4e-25 87.5 1.2 1.2 1 0 0 1 1 1 1 Rad51 HHH_5 PF14520.6 ORY51400.1 - 1.7e-07 31.8 0.5 1.7e-07 31.8 0.5 1.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 ORY51400.1 - 0.00011 21.6 0.2 0.0002 20.8 0.2 1.4 1 0 0 1 1 1 1 KaiC RecA PF00154.21 ORY51400.1 - 0.00012 21.6 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein SAM_LFY PF01698.16 ORY51400.1 - 0.07 13.1 0.0 6.2 6.8 0.0 2.5 1 1 1 2 2 2 0 Floricaula / Leafy protein SAM domain AAA_25 PF13481.6 ORY51400.1 - 0.091 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PAXNEB PF05625.11 ORY51400.1 - 0.3 10.2 0.1 0.3 10.2 0.1 1.8 2 0 0 2 2 2 0 PAXNEB protein Androgen_recep PF02166.16 ORY51400.1 - 9.3 5.0 8.3 12 4.6 8.3 1.2 1 0 0 1 1 1 0 Androgen receptor UQ_con PF00179.26 ORY51401.1 - 5.8e-12 45.5 0.0 1e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF2855 PF11017.8 ORY51402.1 - 3.7e-81 273.5 0.0 4.3e-81 273.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) Calici_PP_N PF08405.11 ORY51402.1 - 0.11 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Viral polyprotein N-terminal DUF4436 PF14494.6 ORY51403.1 - 6.2e-29 101.1 0.8 1.1e-28 100.2 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) DUF2897 PF11446.8 ORY51403.1 - 0.03 14.2 1.2 0.03 14.2 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) Agro_virD5 PF04730.12 ORY51403.1 - 0.092 11.2 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Agrobacterium VirD5 protein DUF2207 PF09972.9 ORY51403.1 - 0.31 9.8 2.2 0.71 8.6 0.8 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3377 PF11857.8 ORY51403.1 - 0.96 9.4 7.1 8 6.5 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) Herpes_UL49_5 PF05702.11 ORY51403.1 - 2.8 8.1 7.6 0.73 10.0 0.5 3.0 3 0 0 3 3 3 0 Herpesvirus UL49.5 envelope/tegument protein DEC-1_N PF04625.13 ORY51404.1 - 0.015 14.3 0.1 0.019 14.0 0.1 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region NAT PF04768.13 ORY51405.1 - 1.5e-42 145.2 0.0 2.3e-42 144.5 0.0 1.3 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 ORY51405.1 - 1.4e-25 90.3 0.1 7.9e-25 87.8 0.1 2.2 2 0 0 2 2 2 1 Amino acid kinase family Semialdhyde_dh PF01118.24 ORY51405.1 - 1.1e-18 67.8 0.0 1.1e-18 67.8 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain BCDHK_Adom3 PF10436.9 ORY51406.1 - 1.5e-58 197.2 0.0 2.9e-58 196.3 0.0 1.5 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 ORY51406.1 - 1e-12 48.5 0.0 2.3e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORY51406.1 - 0.0018 18.1 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Glyco_hydro_31 PF01055.26 ORY51407.1 - 2.2e-65 221.6 5.6 2.8e-59 201.5 3.1 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 DUF5110 PF17137.4 ORY51407.1 - 3.1e-17 62.6 1.1 1e-16 60.9 0.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) DUF4968 PF16338.5 ORY51407.1 - 1.6e-06 28.3 0.5 4.9e-06 26.8 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4968) Gal_mutarotas_2 PF13802.6 ORY51407.1 - 1e-05 25.8 0.9 1e-05 25.8 0.9 2.8 3 0 0 3 3 3 1 Galactose mutarotase-like p450 PF00067.22 ORY51408.1 - 4.5e-74 249.9 0.0 5.1e-74 249.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CBS PF00571.28 ORY51409.1 - 1.9e-24 85.8 7.0 4.3e-08 33.5 0.1 4.7 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 ORY51409.1 - 1.8e-13 50.2 0.0 4.4e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 PB1 domain DUF4436 PF14494.6 ORY51410.1 - 3.4e-31 108.5 2.3 4.8e-31 108.0 2.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) DUF1542 PF07564.11 ORY51410.1 - 0.082 13.0 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) Corona_M PF01635.18 ORY51410.1 - 0.14 11.4 4.2 9.4 5.5 0.1 3.0 3 0 0 3 3 3 0 Coronavirus M matrix/glycoprotein Zot PF05707.12 ORY51411.1 - 0.023 14.3 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) ThrE PF06738.12 ORY51412.1 - 2.1e-21 76.4 18.8 4.3e-14 52.5 0.3 3.6 3 1 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORY51412.1 - 1.9e-05 24.8 20.3 9.7e-05 22.5 12.2 3.0 3 0 0 3 3 3 2 Threonine/Serine exporter, ThrE DUF4436 PF14494.6 ORY51413.1 - 1.7e-24 86.5 1.1 3e-24 85.7 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) MPP6 PF10175.9 ORY51414.1 - 1.5e-19 70.8 7.6 2e-19 70.4 7.6 1.3 1 0 0 1 1 1 1 M-phase phosphoprotein 6 AKAP28 PF14469.6 ORY51414.1 - 0.075 12.8 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 28 kDa A-kinase anchor Cyt-b5 PF00173.28 ORY51415.1 - 6e-18 64.8 0.1 1.1e-17 63.9 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 ORY51415.1 - 1.2e-11 45.1 18.1 1.2e-11 45.1 18.1 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily RIFIN PF02009.16 ORY51416.1 - 0.00031 20.7 0.0 0.00061 19.8 0.0 1.4 1 0 0 1 1 1 1 Rifin SUIM_assoc PF16619.5 ORY51416.1 - 0.0053 16.8 6.2 0.0055 16.8 1.1 3.7 3 1 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 Adeno_E3_CR2 PF02439.15 ORY51416.1 - 0.018 14.8 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.10 ORY51416.1 - 0.035 13.5 0.6 0.087 12.2 0.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 ORY51416.1 - 0.058 14.3 0.1 0.25 12.2 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TTc_toxin_rep PF18807.1 ORY51416.1 - 0.06 13.2 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Tripartite Tc toxins repeat Gram_pos_anchor PF00746.21 ORY51416.1 - 0.073 13.0 1.0 6.5 6.8 0.2 3.1 2 0 0 2 2 2 0 LPXTG cell wall anchor motif APC_u14 PF16635.5 ORY51416.1 - 0.073 13.6 0.1 0.073 13.6 0.1 3.2 2 1 0 2 2 2 0 Unstructured region on APC between SAMP and APC_crr DAP10 PF07213.11 ORY51416.1 - 0.089 12.8 0.7 1.6 8.7 0.0 2.7 2 0 0 2 2 2 0 DAP10 membrane protein PspB PF06667.12 ORY51416.1 - 0.17 11.9 0.0 0.53 10.4 0.0 1.7 1 0 0 1 1 1 0 Phage shock protein B DUF2207 PF09972.9 ORY51416.1 - 0.18 10.5 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Syndecan PF01034.20 ORY51416.1 - 0.37 10.7 1.7 0.69 9.9 1.7 1.3 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.6 ORY51416.1 - 0.41 10.5 0.0 0.41 10.5 0.0 3.1 3 1 1 4 4 4 0 TMEM154 protein family PGA2 PF07543.12 ORY51417.1 - 6.5 6.7 5.8 0.64 10.0 0.3 1.9 2 0 0 2 2 2 0 Protein trafficking PGA2 Glyco_hydro_18 PF00704.28 ORY51418.1 - 1.7e-77 261.2 3.8 2.9e-77 260.4 3.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 RNB PF00773.19 ORY51419.1 - 5.5e-106 354.6 0.0 9.7e-106 353.8 0.0 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 ORY51419.1 - 1.9e-19 69.4 0.0 4.1e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 ORY51419.1 - 1.5e-08 34.8 0.6 1.5e-08 34.8 0.6 2.3 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal Rrp44_CSD1 PF17216.3 ORY51419.1 - 2.8e-06 27.1 0.1 9.2e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Rrp44-like cold shock domain CSD2 PF17876.1 ORY51419.1 - 6e-05 23.1 0.1 0.16 12.2 0.0 3.2 3 0 0 3 3 3 2 Cold shock domain OB_RNB PF08206.11 ORY51419.1 - 6.2e-05 22.6 0.1 0.00014 21.5 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease B OB domain DUF4870 PF09685.10 ORY51420.1 - 0.1 12.7 4.6 0.14 12.3 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) DUF3810 PF12725.7 ORY51420.1 - 0.11 11.9 2.1 0.12 11.7 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Apq12 PF12716.7 ORY51420.1 - 0.79 9.7 14.0 1.3 9.0 14.0 1.3 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis Tmemb_cc2 PF10267.9 ORY51420.1 - 2.3 7.3 4.5 2.4 7.2 4.5 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein RhoGAP PF00620.27 ORY51421.1 - 9.6e-12 45.0 0.0 1.8e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain RhoGAP PF00620.27 ORY51422.1 - 4.9e-09 36.2 0.1 8.6e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain AHH PF14412.6 ORY51422.1 - 0.015 15.3 0.5 0.031 14.3 0.5 1.6 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH RseA_C PF03873.13 ORY51422.1 - 0.35 11.1 5.8 6.4 7.1 1.9 2.6 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain DUF1206 PF06724.11 ORY51423.1 - 0.005 16.9 0.1 0.0056 16.7 0.1 1.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1206) Use1 PF09753.9 ORY51423.1 - 0.01 15.5 0.0 0.011 15.5 0.0 1.0 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF3094 PF11293.8 ORY51423.1 - 0.039 13.7 1.4 0.051 13.3 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) Holin_BlyA PF05102.12 ORY51423.1 - 0.049 13.6 0.1 0.063 13.3 0.1 1.3 1 0 0 1 1 1 0 holin, BlyA family RAMP4 PF06624.12 ORY51423.1 - 0.054 13.6 0.0 0.068 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 FixP_N PF14715.6 ORY51423.1 - 0.18 11.6 3.5 0.33 10.7 3.5 1.4 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP LRR_6 PF13516.6 ORY51424.1 - 1.1e-09 37.5 21.7 1.4 9.1 0.0 9.1 9 0 0 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.7 ORY51424.1 - 3.7e-07 30.4 11.0 0.3 11.6 0.1 6.1 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORY51424.1 - 1.6e-05 24.7 0.4 5.5e-05 23.0 0.3 1.9 2 0 0 2 2 2 1 F-box-like TPR_14 PF13428.6 ORY51424.1 - 0.00011 22.8 2.2 0.032 15.0 0.3 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat LRR_1 PF00560.33 ORY51424.1 - 0.00057 20.1 8.7 0.82 10.5 0.4 6.7 7 0 0 7 7 6 1 Leucine Rich Repeat F-box PF00646.33 ORY51424.1 - 0.0026 17.6 1.0 0.0065 16.3 0.3 2.0 2 0 0 2 2 2 1 F-box domain SAM_Ste50p PF09235.10 ORY51424.1 - 0.0078 16.4 3.0 1 9.6 0.2 3.5 3 0 0 3 3 3 1 Ste50p, sterile alpha motif TPR_16 PF13432.6 ORY51424.1 - 0.01 16.5 3.4 0.01 16.5 3.4 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY51424.1 - 0.014 15.5 0.0 0.73 10.1 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat LRR_8 PF13855.6 ORY51424.1 - 0.016 15.0 3.3 0.68 9.7 0.2 3.9 2 1 1 3 3 3 0 Leucine rich repeat TPR_15 PF13429.6 ORY51424.1 - 0.019 14.2 0.2 0.081 12.1 0.1 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY51424.1 - 0.028 14.2 0.0 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY51424.1 - 0.03 14.8 0.4 0.32 11.5 0.4 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat MYEOV2 PF15004.6 ORY51425.1 - 0.2 12.1 6.7 0.27 11.7 6.7 1.4 1 1 0 1 1 1 0 Myeloma-overexpressed-like RPGR1_C PF18111.1 ORY51426.1 - 4e-18 65.9 1.0 8.7e-18 64.8 0.1 2.1 2 0 0 2 2 2 1 Retinitis pigmentosa G-protein regulator interacting C-terminal C2-C2_1 PF11618.8 ORY51426.1 - 8.6e-17 61.5 0.6 2.7e-07 30.8 0.0 4.7 3 1 1 4 4 4 3 First C2 domain of RPGR-interacting protein 1 Sirohm_synth_C PF14823.6 ORY51426.1 - 0.14 11.8 2.7 17 5.2 0.0 3.6 2 1 1 3 3 3 0 Sirohaem biosynthesis protein C-terminal Prominin PF05478.11 ORY51426.1 - 4 5.3 6.5 8.9 4.1 6.5 1.6 1 0 0 1 1 1 0 Prominin TIR_2 PF13676.6 ORY51428.1 - 1.1e-14 55.0 0.1 1.2e-11 45.2 0.0 2.3 1 1 1 2 2 2 2 TIR domain TIR PF01582.20 ORY51428.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 TIR domain DUF2207 PF09972.9 ORY51428.1 - 1.1 7.9 3.5 0.24 10.1 0.1 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) TssO PF17561.2 ORY51428.1 - 7.3 6.7 7.0 6 7.0 0.2 3.0 3 0 0 3 3 3 0 Type VI secretion system, TssO Forkhead PF00250.18 ORY51429.1 - 2.2e-10 40.6 0.2 4e-10 39.8 0.2 1.4 1 0 0 1 1 1 1 Forkhead domain Ntox3 PF15536.6 ORY51429.1 - 0.092 12.8 0.7 0.24 11.4 0.3 1.9 1 1 1 2 2 2 0 Bacterial toxin 3 Got1 PF04178.12 ORY51430.1 - 1.4e-24 86.7 20.0 2.2e-24 86.1 20.0 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2076 PF09849.9 ORY51430.1 - 0.084 12.9 1.9 0.13 12.3 1.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF2189 PF09955.9 ORY51430.1 - 2.2 8.6 18.1 0.065 13.5 3.8 2.7 2 1 0 2 2 2 0 Predicted integral membrane protein (DUF2189) DUF543 PF04418.12 ORY51431.1 - 6.5e-22 77.3 0.1 8.3e-22 77.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Gram_pos_anchor PF00746.21 ORY51431.1 - 0.09 12.7 0.7 0.19 11.7 0.7 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif ATP_bind_1 PF03029.17 ORY51432.1 - 3.8e-79 265.9 0.0 4.6e-79 265.6 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.6 ORY51432.1 - 0.12 12.8 0.0 0.35 11.3 0.1 1.7 2 0 0 2 2 2 0 AAA domain UMP1 PF05348.11 ORY51433.1 - 8.5e-36 122.8 0.6 1e-35 122.5 0.6 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 DUF4436 PF14494.6 ORY51435.1 - 9.4e-19 67.7 1.9 1.4e-18 67.1 1.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) Peptidase_C13 PF01650.18 ORY51436.1 - 4.8e-43 147.5 0.1 6.2e-43 147.1 0.1 1.1 1 0 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 ORY51436.1 - 0.056 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Mid domain of argonaute CLU PF13236.6 ORY51437.1 - 6.3e-63 212.6 0.0 1.1e-62 211.7 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 ORY51437.1 - 1.6e-45 155.3 0.2 5.5e-45 153.5 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 ORY51437.1 - 1.8e-13 50.6 10.1 1.9e-08 34.4 3.3 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 ORY51437.1 - 1.8e-09 37.2 5.9 0.00085 19.1 0.2 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat CLU_N PF15044.6 ORY51437.1 - 1.7e-07 31.5 0.0 5.9e-07 29.8 0.0 2.0 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_8 PF13181.6 ORY51437.1 - 0.00019 21.4 2.4 0.087 13.1 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF727 PF05303.12 ORY51437.1 - 0.002 18.2 0.0 0.0048 16.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_2 PF07719.17 ORY51437.1 - 0.016 15.2 7.7 4.2 7.7 0.2 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 ORY51437.1 - 0.26 11.5 4.2 13 6.0 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_MalT PF17874.1 ORY51437.1 - 1.7 7.9 7.8 0.72 9.2 0.8 2.5 2 1 1 3 3 3 0 MalT-like TPR region 4HBT PF03061.22 ORY51438.1 - 3.1e-08 33.9 0.0 4.6e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF2632 PF10943.8 ORY51438.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2632) 4HBT PF03061.22 ORY51439.1 - 2.2e-08 34.3 0.0 4.7e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Glyco_hydro_18 PF00704.28 ORY51440.1 - 1.3e-07 31.6 18.6 4.6e-07 29.9 0.2 4.1 3 1 1 4 4 4 2 Glycosyl hydrolases family 18 Mucin PF01456.17 ORY51440.1 - 1.8 8.5 40.9 5.2 7.1 40.9 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein Ras PF00071.22 ORY51441.1 - 7.5e-19 67.9 0.1 1.2e-18 67.2 0.1 1.3 1 0 0 1 1 1 1 Ras family Septin PF00735.18 ORY51441.1 - 0.0073 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Septin SCP2 PF02036.17 ORY51442.1 - 2.6e-26 92.1 1.4 3e-26 91.9 1.4 1.0 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 ORY51442.1 - 1.5e-05 25.3 0.8 2.4e-05 24.6 0.6 1.5 1 1 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 ORY51442.1 - 0.028 14.8 0.1 0.035 14.5 0.1 1.2 1 0 0 1 1 1 0 Sterol carrier protein domain Sec61_beta PF03911.16 ORY51443.1 - 1.8e-16 59.9 0.9 2.8e-16 59.3 0.9 1.3 1 0 0 1 1 1 1 Sec61beta family Bac_surface_Ag PF01103.23 ORY51444.1 - 1.6e-45 156.0 1.2 1.9e-45 155.8 1.2 1.1 1 0 0 1 1 1 1 Surface antigen LRR_4 PF12799.7 ORY51445.1 - 2.5e-10 40.4 4.8 3e-05 24.3 0.4 3.5 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORY51445.1 - 6.2e-08 32.3 0.6 0.00039 20.0 0.0 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 ORY51445.1 - 9.4e-08 31.7 17.8 2e-05 24.2 3.0 3.0 1 1 3 4 4 4 3 Leucine rich repeat Helo_like_N PF17111.5 ORY51445.1 - 0.011 15.1 0.1 0.023 14.0 0.1 1.5 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins LRR_1 PF00560.33 ORY51445.1 - 5.1 8.0 5.3 1.3e+02 3.7 0.1 3.8 3 1 0 3 3 3 0 Leucine Rich Repeat Brix PF04427.18 ORY51448.1 - 1.6e-28 100.1 0.0 2.5e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 Brix domain Mitochondr_Som1 PF11093.8 ORY51449.1 - 6e-06 26.2 1.9 2.6e-05 24.1 1.9 1.8 1 1 0 1 1 1 1 Mitochondrial export protein Som1 Lipoxygenase PF00305.19 ORY51451.1 - 1.7e-25 89.6 0.0 2.4e-16 59.3 0.0 2.3 2 1 0 2 2 2 2 Lipoxygenase 4HBT PF03061.22 ORY51452.1 - 7.2e-12 45.5 0.1 1.4e-11 44.6 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily PP2C PF00481.21 ORY51453.1 - 6.2e-34 117.8 0.0 2e-32 112.8 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 ORY51453.1 - 0.003 17.2 0.0 0.017 14.8 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C HEAT_2 PF13646.6 ORY51455.1 - 6.1e-06 26.5 6.2 0.0076 16.6 0.1 5.4 5 1 0 5 5 5 1 HEAT repeats MMS19_N PF14500.6 ORY51455.1 - 8.5e-05 22.3 2.1 0.00036 20.2 0.1 3.1 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.22 ORY51455.1 - 0.00031 20.8 9.7 1.2 9.6 0.0 7.1 8 0 0 8 8 8 1 HEAT repeat Adaptin_N PF01602.20 ORY51455.1 - 0.0013 17.4 11.5 0.0055 15.3 0.1 4.6 5 1 0 5 5 5 1 Adaptin N terminal region HEAT_EZ PF13513.6 ORY51455.1 - 0.0092 16.5 0.8 22 5.7 0.0 4.8 4 0 0 4 4 4 1 HEAT-like repeat Cnd3 PF12719.7 ORY51455.1 - 0.019 14.1 6.5 1.8 7.7 0.0 4.6 4 1 0 5 5 5 0 Nuclear condensing complex subunits, C-term domain EF-hand_1 PF00036.32 ORY51456.1 - 1.1e-33 112.3 16.8 2.8e-09 35.9 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORY51456.1 - 2.6e-30 104.7 10.2 6.5e-16 58.6 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY51456.1 - 3.6e-27 91.9 10.0 2.3e-09 36.4 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 ORY51456.1 - 2.1e-25 88.3 14.9 5.2e-12 45.4 1.1 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 ORY51456.1 - 1.5e-16 60.5 0.1 1.2e-07 31.9 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 ORY51456.1 - 3.5e-15 54.7 18.5 7.1e-06 25.3 0.2 4.5 4 1 0 4 4 4 4 EF hand EF-hand_4 PF12763.7 ORY51456.1 - 6.2e-07 29.3 4.9 0.034 14.1 0.6 3.3 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 ORY51456.1 - 1.5e-05 25.3 1.0 0.012 15.9 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region SurA_N_3 PF13624.6 ORY51456.1 - 0.00012 21.9 1.6 0.083 12.7 0.3 2.1 2 0 0 2 2 2 2 SurA N-terminal domain EF-hand_14 PF17959.1 ORY51456.1 - 0.00013 22.2 1.5 0.59 10.5 0.2 2.6 2 1 0 2 2 2 2 EF-hand domain Sigma54_CBD PF04963.13 ORY51456.1 - 0.00064 19.6 0.3 0.00082 19.3 0.3 1.1 1 0 0 1 1 1 1 Sigma-54 factor, core binding domain SurA_N_2 PF13623.6 ORY51456.1 - 0.011 15.6 0.8 1.8 8.5 0.1 2.4 2 1 0 2 2 2 0 SurA N-terminal domain FlgD PF03963.14 ORY51456.1 - 0.024 14.9 1.9 0.079 13.3 1.0 2.3 2 1 0 2 2 2 0 Flagellar hook capping protein - N-terminal region Caleosin PF05042.13 ORY51456.1 - 0.025 14.5 1.2 7.8 6.4 0.0 3.5 1 1 3 4 4 4 0 Caleosin related protein SUB1_ProdP9 PF18213.1 ORY51456.1 - 0.029 14.2 0.3 0.062 13.2 0.3 1.5 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 DUF853 PF05872.12 ORY51456.1 - 0.05 12.2 0.2 0.59 8.7 0.1 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) TerB PF05099.13 ORY51456.1 - 0.09 12.7 2.5 1.1 9.2 0.1 2.7 1 1 2 3 3 3 0 Tellurite resistance protein TerB Phage_holin_6_1 PF09682.10 ORY51456.1 - 0.15 12.5 0.8 17 5.9 0.0 2.3 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF21 PF01595.20 ORY51456.1 - 0.2 11.3 0.8 1.6 8.4 0.2 2.2 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain ParD_antitoxin PF03693.14 ORY51456.1 - 0.22 11.9 1.3 6.5 7.2 0.4 2.4 1 1 1 2 2 2 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH Asp PF00026.23 ORY51457.1 - 6.4e-18 65.2 5.8 9.6e-18 64.7 5.8 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY51457.1 - 0.015 15.5 4.1 0.015 15.5 4.1 2.9 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal LRR_6 PF13516.6 ORY51459.1 - 1.9e-08 33.7 0.4 0.056 13.5 0.0 5.7 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.7 ORY51459.1 - 1.8e-06 28.1 9.1 0.14 12.6 0.1 4.8 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY51459.1 - 0.06 13.9 7.7 3.6 8.5 0.0 5.5 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 ORY51459.1 - 2.5 7.9 6.8 63 3.4 0.8 4.3 3 2 0 3 3 3 0 Leucine rich repeat zf-C2H2 PF00096.26 ORY51460.1 - 2e-10 40.5 9.3 2e-05 24.8 2.9 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY51460.1 - 8.4e-09 35.5 8.3 0.00062 20.4 2.2 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY51460.1 - 1.1e-06 28.8 11.8 0.00022 21.5 1.4 2.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY51460.1 - 4.9e-06 26.7 3.4 0.0052 17.0 0.6 2.1 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 ORY51460.1 - 0.00011 22.0 0.8 0.016 15.1 0.0 2.2 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-met PF12874.7 ORY51460.1 - 0.0047 17.3 4.6 0.16 12.4 0.2 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PyrI_C PF02748.15 ORY51460.1 - 0.0056 16.6 1.1 1.4 8.9 0.1 2.3 2 0 0 2 2 2 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_3rep PF18868.1 ORY51460.1 - 0.0079 16.9 0.5 1.3 9.7 0.0 2.0 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats C1_4 PF07975.12 ORY51460.1 - 0.021 15.1 3.0 0.026 14.8 1.9 1.7 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2HE PF16278.5 ORY51460.1 - 0.023 15.2 1.9 0.023 15.2 1.9 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger C1_2 PF03107.16 ORY51460.1 - 0.031 14.6 5.4 0.044 14.1 0.6 2.3 1 1 1 2 2 2 0 C1 domain zf-AN1 PF01428.16 ORY51460.1 - 0.032 14.4 3.6 3.5 7.9 0.1 2.4 2 0 0 2 2 2 0 AN1-like Zinc finger zf-C2H2_11 PF16622.5 ORY51460.1 - 0.05 13.4 1.7 5.4 6.9 0.0 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 ORY51460.1 - 0.052 13.9 3.2 1.1 9.6 0.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.21 ORY51460.1 - 0.19 11.9 6.9 0.64 10.2 0.9 2.2 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2_6 PF13912.6 ORY51460.1 - 0.22 11.6 6.6 0.85 9.7 2.0 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 ORY51460.1 - 0.4 10.8 5.0 3.5 7.8 4.0 2.2 1 1 1 2 2 2 0 Zinc ribbon domain DUF629 PF04780.12 ORY51460.1 - 1 7.8 5.9 2.4 6.6 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zinc_ribbon_4 PF13717.6 ORY51460.1 - 1.2 9.2 8.6 25 4.9 0.2 3.0 2 1 0 2 2 2 0 zinc-ribbon domain zf-BED PF02892.15 ORY51460.1 - 1.5 8.9 6.6 1.7 8.7 0.7 2.3 1 1 1 2 2 2 0 BED zinc finger Amelogenin PF02948.15 ORY51461.1 - 0.34 11.6 6.8 1.3 9.7 1.1 2.1 2 0 0 2 2 2 0 Amelogenin DPBB_1 PF03330.18 ORY51462.1 - 3e-06 27.4 0.2 1.5e-05 25.2 0.2 2.2 1 1 0 1 1 1 1 Lytic transglycolase DUF1652 PF07865.11 ORY51462.1 - 2.3 8.1 3.7 16 5.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1652) Miga PF10265.9 ORY51462.1 - 2.4 7.0 7.8 3.2 6.6 7.8 1.1 1 0 0 1 1 1 0 Mitoguardin DUF515 PF04415.12 ORY51462.1 - 3 6.1 11.4 4 5.7 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF3533 PF12051.8 ORY51462.1 - 5.5 5.8 8.4 7.8 5.3 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) GMP_PDE_delta PF05351.11 ORY51463.1 - 2.2e-37 128.5 0.2 4e-37 127.7 0.2 1.4 1 1 0 1 1 1 1 GMP-PDE, delta subunit SH3_1 PF00018.28 ORY51464.1 - 1.4e-14 53.4 0.0 2.1e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY51464.1 - 3.9e-09 36.0 0.0 7.3e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 ORY51464.1 - 1.4e-08 34.4 0.0 2.1e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain MFS_1 PF07690.16 ORY51465.1 - 2.5e-32 112.2 34.4 2.9e-28 98.8 21.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY51465.1 - 2.8e-30 105.6 12.4 8.5e-28 97.4 8.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 ORY51465.1 - 0.0033 15.9 2.0 0.0054 15.2 2.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF21 PF01595.20 ORY51465.1 - 0.85 9.3 7.1 0.68 9.6 0.2 3.5 2 1 0 3 3 3 0 Cyclin M transmembrane N-terminal domain F-box PF00646.33 ORY51466.1 - 3.7e-05 23.5 3.0 0.062 13.2 0.4 2.8 2 0 0 2 2 2 2 F-box domain F-box_4 PF15966.5 ORY51466.1 - 4.9e-05 23.2 0.0 0.066 13.1 0.0 2.6 2 0 0 2 2 2 2 F-box F-box-like PF12937.7 ORY51466.1 - 0.0075 16.1 4.4 0.46 10.4 0.9 3.2 2 1 0 2 2 2 2 F-box-like DUF2499 PF10693.9 ORY51467.1 - 0.018 15.3 0.2 0.035 14.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2499) eIF3g PF12353.8 ORY51468.1 - 0.014 15.8 0.1 0.014 15.8 0.1 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G FdhD-NarQ PF02634.15 ORY51468.1 - 0.56 9.8 2.2 1.4 8.5 0.0 2.4 2 1 1 3 3 3 0 FdhD/NarQ family SET PF00856.28 ORY51470.1 - 6e-06 26.7 0.0 1.7e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 SET domain MFS_1 PF07690.16 ORY51471.1 - 4.4e-37 127.8 41.7 6e-27 94.5 18.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY51471.1 - 1.3e-31 110.0 19.3 1.6e-31 109.7 19.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter LptF_LptG PF03739.14 ORY51471.1 - 0.012 14.5 0.2 0.012 14.5 0.2 2.1 2 1 0 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG ADD_DNMT3 PF17980.1 ORY51472.1 - 0.0056 16.6 1.2 0.0056 16.6 1.2 3.2 2 1 2 4 4 4 1 Cysteine rich ADD domain in DNMT3 GFO_IDH_MocA PF01408.22 ORY51473.1 - 5.6e-23 82.0 0.1 1.1e-22 81.1 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Helitron_like_N PF14214.6 ORY51473.1 - 0.0067 16.7 0.0 0.08 13.2 0.0 2.2 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus Big_1 PF02369.16 ORY51473.1 - 0.014 15.4 0.2 0.041 13.9 0.2 1.8 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 1) RPN6_C_helix PF18503.1 ORY51473.1 - 0.078 12.7 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN6 C-terminal helix domain DUF4567 PF15131.6 ORY51473.1 - 0.17 11.9 0.2 0.61 10.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4567) MFS_1 PF07690.16 ORY51474.1 - 1.6e-06 27.3 13.4 1.6e-06 27.3 13.4 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2255 PF10012.9 ORY51474.1 - 0.078 13.1 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) 7tm_7 PF08395.12 ORY51474.1 - 0.75 8.9 18.0 0.2 10.8 4.2 2.7 3 0 0 3 3 3 0 7tm Chemosensory receptor DAGK_cat PF00781.24 ORY51475.1 - 2.7e-23 81.9 0.0 5.7e-23 80.9 0.0 1.5 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Pox_T4_C PF04490.12 ORY51475.1 - 0.036 14.2 0.1 0.08 13.1 0.1 1.5 1 0 0 1 1 1 0 Poxvirus T4 protein, C terminus DUF5130 PF17174.4 ORY51475.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5130) HisKA_2 PF07568.12 ORY51475.1 - 0.13 12.4 0.1 0.28 11.3 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase MARVEL PF01284.23 ORY51478.1 - 0.0017 18.4 1.5 0.0017 18.4 1.5 2.2 1 1 1 2 2 2 2 Membrane-associating domain DUF2628 PF10947.8 ORY51478.1 - 1.4 9.4 8.4 0.92 9.9 3.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) DUF3808 PF10300.9 ORY51479.1 - 1.4e-20 73.5 0.0 2.2e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Ank_2 PF12796.7 ORY51480.1 - 4.7e-20 72.0 0.0 1.1e-12 48.3 0.1 3.2 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY51480.1 - 5.2e-20 71.5 0.1 2.4e-12 47.1 0.1 3.7 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 ORY51480.1 - 2.3e-19 68.9 1.5 5.3e-05 23.5 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 ORY51480.1 - 1.2e-17 63.7 0.7 4.8e-07 29.9 0.1 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY51480.1 - 1.9e-16 58.4 0.2 0.00061 20.1 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat HXXSHH PF07586.11 ORY51485.1 - 0.43 10.1 6.6 0.33 10.5 3.7 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1552) zf-MIZ PF02891.20 ORY51486.1 - 2.6e-12 46.3 6.2 4.8e-12 45.4 6.2 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 ORY51486.1 - 9.7e-06 25.3 3.5 2e-05 24.3 3.5 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 ORY51486.1 - 0.0062 16.6 3.2 0.06 13.4 1.1 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1149 PF06619.11 ORY51486.1 - 0.012 15.9 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1149) zf-RING_2 PF13639.6 ORY51486.1 - 0.048 14.0 6.8 0.076 13.4 3.8 2.3 2 0 0 2 2 2 0 Ring finger domain TauD PF02668.16 ORY51487.1 - 1.4e-40 139.8 0.0 2.2e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 ORY51487.1 - 1.5e-15 57.6 0.2 9.3e-13 48.6 0.1 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF971) CsiD PF08943.10 ORY51487.1 - 0.1 11.7 0.0 0.32 10.1 0.0 1.7 2 0 0 2 2 2 0 CsiD SNARE_assoc PF09335.11 ORY51488.1 - 4.5e-19 69.1 7.4 4.5e-19 69.1 7.4 2.8 3 0 0 3 3 3 1 SNARE associated Golgi protein Yippee-Mis18 PF03226.14 ORY51489.1 - 3.7e-15 56.0 2.1 4.6e-15 55.7 2.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SNAD2 PF18745.1 ORY51489.1 - 0.049 13.3 0.0 0.066 12.9 0.0 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 2 Endonuclease_7 PF02945.15 ORY51489.1 - 0.13 12.3 4.1 0.63 10.0 4.1 1.9 1 1 0 1 1 1 0 Recombination endonuclease VII Jas PF16135.5 ORY51489.1 - 4.9 7.4 6.6 1.2 9.3 0.7 2.2 1 1 1 2 2 2 0 TPL-binding domain in jasmonate signalling Chs7 PF12271.8 ORY51490.1 - 1.1e-92 310.5 19.2 1.3e-92 310.3 19.2 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Pep3_Vps18 PF05131.14 ORY51491.1 - 6.6e-42 142.8 1.3 1.6e-41 141.6 0.6 2.1 3 0 0 3 3 3 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 ORY51491.1 - 5.7e-16 58.7 6.3 8.7e-13 48.4 2.7 2.9 2 1 0 2 2 2 2 Region in Clathrin and VPS Vps39_2 PF10367.9 ORY51491.1 - 5.9e-07 29.9 1.1 5.9e-07 29.9 1.1 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Zn_ribbon_17 PF17120.5 ORY51491.1 - 6.4e-05 22.5 2.5 0.00011 21.7 2.5 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 ORY51491.1 - 0.00011 21.8 3.0 0.00024 20.8 3.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 ORY51491.1 - 0.00042 20.6 2.3 0.00073 19.8 2.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY51491.1 - 0.0013 18.5 3.2 0.0023 17.7 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY51491.1 - 0.0026 17.7 2.1 0.0044 17.0 2.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 ORY51491.1 - 0.021 14.9 3.6 0.043 13.9 3.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 ORY51491.1 - 0.021 14.7 2.7 0.042 13.7 2.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY51491.1 - 0.035 14.4 1.6 0.072 13.4 1.6 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3H2C3 PF17122.5 ORY51491.1 - 0.072 13.1 2.4 0.14 12.2 2.4 1.5 1 0 0 1 1 1 0 Zinc-finger Lipase_GDSL PF00657.22 ORY51491.1 - 0.091 12.7 0.1 1.4 8.8 0.1 2.7 3 1 0 3 3 3 0 GDSL-like Lipase/Acylhydrolase XhlA PF10779.9 ORY51491.1 - 0.11 12.7 2.7 0.43 10.8 2.7 2.0 1 0 0 1 1 1 0 Haemolysin XhlA Zf_RING PF16744.5 ORY51491.1 - 0.35 11.0 1.4 0.66 10.1 1.4 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger CBS PF00571.28 ORY51492.1 - 1.5e-23 83.0 3.6 1.8e-08 34.7 0.1 4.8 5 0 0 5 5 5 4 CBS domain RRM_1 PF00076.22 ORY51493.1 - 7.1e-48 160.3 0.0 9.3e-20 70.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 ORY51493.1 - 5.3e-11 42.2 0.0 0.00015 21.3 0.0 3.2 1 1 2 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY51493.1 - 2.8e-09 36.7 0.0 5.7e-06 26.1 0.0 3.0 3 0 0 3 3 3 2 Occluded RNA-recognition motif SET_assoc PF11767.8 ORY51493.1 - 9e-05 22.0 0.0 0.19 11.4 0.0 2.4 2 0 0 2 2 2 2 Histone lysine methyltransferase SET associated RRM_7 PF16367.5 ORY51493.1 - 0.0075 16.4 0.0 0.17 12.0 0.0 3.0 3 1 0 3 3 3 1 RNA recognition motif NUT PF12881.7 ORY51493.1 - 0.019 13.4 0.8 0.027 12.9 0.8 1.1 1 0 0 1 1 1 0 NUT protein OB_RNB PF08206.11 ORY51493.1 - 0.035 13.8 0.2 1.7 8.4 0.0 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain Limkain-b1 PF11608.8 ORY51493.1 - 0.14 12.3 0.1 20 5.4 0.0 2.6 2 0 0 2 2 2 0 Limkain b1 UCR_hinge PF02320.16 ORY51494.1 - 1.4e-10 41.2 6.5 1.6e-10 41.1 6.5 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Euplotes_phero PF05842.11 ORY51494.1 - 0.037 14.6 0.8 0.042 14.4 0.8 1.0 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein Cullin_binding PF03556.15 ORY51495.1 - 3.1e-34 118.0 6.2 6.1e-34 117.1 6.2 1.5 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 ORY51495.1 - 6.3e-13 48.3 1.9 8.4e-13 47.9 0.4 2.1 2 0 0 2 2 2 1 UBA-like domain CSN8_PSD8_EIF3K PF10075.9 ORY51495.1 - 0.046 13.7 0.1 0.15 12.1 0.1 1.8 2 0 0 2 2 2 0 CSN8/PSMD8/EIF3K family BLI1 PF17324.2 ORY51495.1 - 1.7 9.3 6.3 8.5 7.1 1.8 2.3 2 0 0 2 2 2 0 BLOC-1 interactor 1 Dynamin_N PF00350.23 ORY51496.1 - 4.5e-47 160.2 0.0 8.2e-47 159.4 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 ORY51496.1 - 1.3e-18 67.2 0.0 1.5e-15 57.2 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 ORY51496.1 - 2.8e-06 27.4 0.0 7.1e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase CPSF73-100_C PF11718.8 ORY51496.1 - 0.019 14.5 0.2 0.05 13.1 0.2 1.7 1 1 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Se-cys_synth_N PF12390.8 ORY51496.1 - 0.023 14.9 0.6 1.8 8.8 0.0 3.8 4 0 0 4 4 4 0 Selenocysteine synthase N terminal AAA_16 PF13191.6 ORY51496.1 - 0.024 15.0 0.5 0.13 12.6 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 ORY51496.1 - 0.026 14.3 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 ORY51496.1 - 0.065 13.7 0.2 1.2 9.6 0.0 2.8 3 0 0 3 3 3 0 ABC transporter Roc PF08477.13 ORY51496.1 - 0.11 12.7 0.0 0.49 10.6 0.0 2.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 ORY51496.1 - 0.15 11.7 0.1 0.15 11.7 0.1 2.0 3 0 0 3 3 3 0 AAA ATPase domain DUF4709 PF15821.5 ORY51497.1 - 3.3e-05 24.1 3.3 3.3e-05 24.1 3.3 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4709) ABC2_membrane PF01061.24 ORY51499.1 - 8.7e-74 247.5 50.2 7.5e-40 136.6 21.3 2.5 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 ORY51499.1 - 2.9e-34 118.5 0.0 1.8e-16 60.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 ORY51499.1 - 3e-25 88.0 6.4 7.4e-18 64.2 0.0 3.0 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 ORY51499.1 - 8e-08 31.8 6.8 8e-08 31.8 6.8 3.3 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 ORY51499.1 - 8.6e-07 29.0 0.0 0.0023 17.8 0.0 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORY51499.1 - 2.4e-05 24.8 0.1 0.3 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 ORY51499.1 - 4.5e-05 23.4 0.0 0.024 14.6 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 ORY51499.1 - 0.00011 21.8 1.0 0.01 15.6 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_trans_N PF14510.6 ORY51499.1 - 0.00023 21.7 0.0 0.00053 20.5 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_22 PF13401.6 ORY51499.1 - 0.00036 20.8 0.0 0.75 10.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 ORY51499.1 - 0.0097 15.5 0.0 0.086 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 ORY51499.1 - 0.04 13.3 0.3 1.3 8.4 0.1 3.0 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain NB-ARC PF00931.22 ORY51499.1 - 0.047 12.9 0.0 0.21 10.7 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.23 ORY51499.1 - 0.11 12.6 0.2 10 6.2 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.6 ORY51499.1 - 0.13 12.5 0.0 0.53 10.5 0.0 2.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit cobW PF02492.19 ORY51499.1 - 0.13 11.8 0.4 0.82 9.2 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 ORY51499.1 - 0.2 12.1 3.5 9 6.7 0.2 3.7 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Lipase_3 PF01764.25 ORY51500.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.7 ORY51501.1 - 8.3e-07 29.8 0.3 1.2e-06 29.3 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY51501.1 - 2e-05 24.4 0.1 4.1e-05 23.4 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.12 ORY51501.1 - 0.021 14.7 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) TAL_effector PF03377.13 ORY51501.1 - 0.039 14.3 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 TAL effector repeat PGAP1 PF07819.13 ORY51501.1 - 0.044 13.5 0.3 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein K_trans PF02705.16 ORY51501.1 - 0.062 11.8 0.1 0.09 11.3 0.1 1.1 1 0 0 1 1 1 0 K+ potassium transporter Abhydrolase_6 PF12697.7 ORY51502.1 - 0.00049 20.8 0.8 0.0032 18.1 0.7 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY51502.1 - 0.0035 17.0 0.0 0.0074 16.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold RRN3 PF05327.11 ORY51503.1 - 5.4e-131 437.9 0.0 1.3e-130 436.6 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 UreF PF01730.16 ORY51503.1 - 0.0063 17.1 5.8 0.03 14.9 0.2 2.7 2 0 0 2 2 2 1 UreF Lipase_3 PF01764.25 ORY51504.1 - 0.031 14.2 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Acyl_transf_1 PF00698.21 ORY51504.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Acyl transferase domain Endonuclease_5 PF04493.14 ORY51505.1 - 7.3e-24 84.5 0.3 8e-14 51.8 0.1 2.1 1 1 1 2 2 2 2 Endonuclease V DUF4244 PF14029.6 ORY51505.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) LSM PF01423.22 ORY51506.1 - 4.6e-19 67.9 0.0 5.3e-19 67.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORY51506.1 - 0.051 13.7 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain Hfq PF17209.3 ORY51506.1 - 0.089 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Hfq protein HTH_24 PF13412.6 ORY51507.1 - 0.074 12.6 0.0 2.8 7.6 0.0 2.8 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding Roughex PF06020.11 ORY51507.1 - 0.44 9.6 1.8 0.78 8.8 1.8 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Med12 PF09497.10 ORY51508.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Transcription mediator complex subunit Med12 PAT1 PF09770.9 ORY51510.1 - 0.93 7.7 17.5 1.2 7.3 17.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 ORY51510.1 - 1.9 8.4 29.3 2.8 7.8 29.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF515 PF04415.12 ORY51512.1 - 0.029 12.8 0.0 0.049 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SP_C-Propep PF08999.10 ORY51512.1 - 0.07 12.9 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide HTH_AraC PF00165.23 ORY51513.1 - 0.069 13.3 0.0 12 6.1 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family LEA_2 PF03168.13 ORY51513.1 - 0.19 12.3 0.9 4.8 7.8 0.2 2.7 3 0 0 3 3 3 0 Late embryogenesis abundant protein OapA_N PF08525.11 ORY51515.1 - 0.05 13.6 1.3 0.11 12.5 1.3 1.6 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif CAP_N PF01213.19 ORY51516.1 - 8.1 5.8 6.0 13 5.1 6.0 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Cu_bind_like PF02298.17 ORY51517.1 - 6.4e-08 32.5 0.0 1.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Plastocyanin-like domain Glycoprotein PF03409.15 ORY51517.1 - 0.072 11.9 6.7 0.091 11.6 6.7 1.2 1 0 0 1 1 1 0 Transmembrane glycoprotein GLTT PF01744.20 ORY51517.1 - 0.088 12.6 0.9 0.088 12.6 0.9 1.9 2 0 0 2 2 2 0 GLTT repeat (6 copies) DUF4512 PF14975.6 ORY51517.1 - 0.75 10.6 2.8 1.4 9.7 2.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Kinesin PF00225.23 ORY51518.1 - 3.5e-111 371.3 0.5 5.5e-111 370.7 0.5 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY51518.1 - 1.5e-25 89.9 0.0 3.5e-25 88.7 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Fib_alpha PF08702.10 ORY51518.1 - 0.033 14.4 1.7 0.1 12.8 1.7 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Spc24 PF08286.11 ORY51518.1 - 0.04 14.1 0.4 0.2 11.9 0.4 2.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Lzipper-MIP1 PF14389.6 ORY51518.1 - 0.1 12.9 4.5 17 5.8 3.3 3.7 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 AAA_24 PF13479.6 ORY51518.1 - 0.12 12.1 0.3 13 5.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 ORY51519.1 - 6.9e-45 153.5 0.0 1e-44 152.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY51519.1 - 5.2e-21 75.1 0.0 7.4e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 ORY51519.1 - 0.02 14.8 0.0 0.4 10.6 0.0 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 ORY51519.1 - 0.052 12.3 0.0 0.48 9.1 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase Peptidase_M8 PF01457.16 ORY51520.1 - 0.077 11.7 2.1 0.14 10.8 2.1 1.4 1 0 0 1 1 1 0 Leishmanolysin DUF1548 PF07579.11 ORY51520.1 - 0.43 10.9 2.7 1.1 9.6 2.7 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) Pkinase PF00069.25 ORY51521.1 - 9.3e-36 123.5 0.0 4.1e-35 121.4 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY51521.1 - 3.4e-17 62.6 0.1 2.6e-16 59.7 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 ORY51521.1 - 2.3e-05 23.9 0.1 4.1e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY51521.1 - 0.036 14.0 0.3 0.077 12.9 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY51521.1 - 0.087 11.7 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 ORY51521.1 - 0.17 11.4 0.2 0.28 10.8 0.2 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase TruD PF01142.18 ORY51522.1 - 1.9e-72 244.4 0.0 7.3e-72 242.5 0.0 1.9 1 1 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) PurS PF02700.14 ORY51522.1 - 0.16 12.2 0.2 0.38 11.0 0.2 1.6 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase DUF1126 PF06565.12 ORY51523.1 - 1.3e-100 330.3 2.9 1.4e-35 121.3 0.0 3.1 3 0 0 3 3 3 3 DUF1126 PH-like domain RHH_7 PF16777.5 ORY51523.1 - 0.023 15.1 1.1 17 5.9 0.0 3.9 3 1 1 4 4 4 0 Transcriptional regulator, RHH-like, CopG VHS PF00790.19 ORY51524.1 - 3.9e-32 111.0 1.2 4.5e-31 107.6 0.0 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 ORY51524.1 - 2.8e-17 62.6 9.2 5.9e-17 61.6 9.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 ORY51524.1 - 8.5e-06 25.3 12.9 0.0092 15.8 2.7 2.6 2 0 0 2 2 2 2 Ubiquitin interaction motif FYVE_2 PF02318.16 ORY51524.1 - 0.00032 20.9 4.1 0.00065 19.9 4.1 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger DZR PF12773.7 ORY51524.1 - 0.0052 16.8 9.1 0.36 10.9 0.3 2.5 1 1 1 2 2 2 2 Double zinc ribbon zinc_ribbon_9 PF14369.6 ORY51524.1 - 0.031 14.5 6.6 0.72 10.2 1.2 2.7 2 1 0 2 2 2 0 zinc-ribbon LRR_8 PF13855.6 ORY51526.1 - 6.6e-11 41.8 8.3 9.7e-09 34.9 2.0 3.0 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 ORY51526.1 - 7.1e-06 26.3 14.0 0.021 15.2 1.0 4.7 4 1 0 5 5 5 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORY51526.1 - 0.001 18.9 2.5 0.0065 16.3 0.0 3.1 3 0 0 3 3 3 1 F-box-like Tektin PF03148.14 ORY51526.1 - 0.0041 15.9 3.4 0.0058 15.4 3.4 1.1 1 0 0 1 1 1 1 Tektin family F-box PF00646.33 ORY51526.1 - 0.007 16.2 0.1 0.053 13.4 0.0 2.4 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 ORY51526.1 - 0.011 16.2 14.0 7 7.6 0.1 5.7 4 1 1 5 5 5 0 Leucine Rich Repeat Jnk-SapK_ap_N PF09744.9 ORY51526.1 - 0.039 14.2 3.9 0.059 13.6 3.9 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF3135 PF11333.8 ORY51526.1 - 0.31 11.3 5.2 0.13 12.5 1.3 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3135) CLZ PF16526.5 ORY51526.1 - 0.72 10.3 3.7 15 6.0 0.5 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels YabA PF06156.13 ORY51526.1 - 2.3 8.9 4.7 5.4 7.7 4.5 1.7 1 1 0 1 1 1 0 Initiation control protein YabA DUF4763 PF15960.5 ORY51526.1 - 2.8 7.2 12.1 2.7 7.2 3.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) DUF1043 PF06295.12 ORY51526.1 - 3.3 7.7 10.9 2.5 8.1 4.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) Spc24 PF08286.11 ORY51526.1 - 9.2 6.6 8.2 20 5.5 1.5 2.5 2 1 1 3 3 2 0 Spc24 subunit of Ndc80 LRR_8 PF13855.6 ORY51527.1 - 8.2e-11 41.5 16.9 3e-07 30.1 6.6 3.1 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.33 ORY51527.1 - 3.2e-06 26.9 16.5 0.32 11.7 0.5 6.1 5 1 0 5 5 5 3 Leucine Rich Repeat LRR_4 PF12799.7 ORY51527.1 - 0.0001 22.6 15.9 0.0064 16.9 2.6 4.2 2 1 4 6 6 6 4 Leucine Rich repeats (2 copies) F-box PF00646.33 ORY51527.1 - 0.0043 16.9 0.0 0.0043 16.9 0.0 2.6 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 ORY51527.1 - 0.027 14.4 0.3 0.027 14.4 0.3 2.7 3 0 0 3 3 3 0 F-box-like Rtt106 PF08512.12 ORY51528.1 - 1.6e-15 57.3 0.0 3.9e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Histone chaperone Rttp106-like CDC45 PF02724.14 ORY51528.1 - 0.35 9.1 20.6 0.67 8.2 20.6 1.4 1 0 0 1 1 1 0 CDC45-like protein tRNA-synt_2_TM PF16995.5 ORY51529.1 - 0.023 14.4 1.1 0.037 13.7 1.1 1.3 1 0 0 1 1 1 0 Transmembrane region of lysyl-tRNA synthetase Ephrin_rec_like PF07699.13 ORY51530.1 - 1.1e-12 47.4 32.5 1.6e-06 27.8 6.5 5.2 2 2 3 5 5 5 4 Putative ephrin-receptor like VSP PF03302.13 ORY51530.1 - 1.7 7.4 32.4 0.024 13.5 10.0 2.5 1 1 1 2 2 2 0 Giardia variant-specific surface protein WD40 PF00400.32 ORY51531.1 - 1.1e-14 54.6 12.0 1.4e-08 35.2 0.3 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY51531.1 - 0.00029 21.1 0.0 0.055 13.8 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain SURF4 PF02077.15 ORY51532.1 - 2.9e-56 191.0 3.5 3.2e-56 190.9 3.5 1.0 1 0 0 1 1 1 1 SURF4 family NMN_transporter PF04973.12 ORY51532.1 - 0.0025 17.8 7.6 0.0045 17.0 7.6 1.5 1 1 0 1 1 1 1 Nicotinamide mononucleotide transporter HR_lesion PF05514.11 ORY51532.1 - 0.003 17.7 1.2 0.007 16.5 1.2 1.6 1 1 0 1 1 1 1 HR-like lesion-inducing Calcyon PF06387.11 ORY51532.1 - 0.077 13.0 0.2 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) DUF3488 PF11992.8 ORY51532.1 - 0.6 9.0 7.9 7.1 5.5 7.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3488) DoxX PF07681.12 ORY51532.1 - 3.6 8.2 12.0 0.14 12.8 4.3 2.4 2 1 1 3 3 3 0 DoxX Arylsulfotran_2 PF14269.6 ORY51533.1 - 0.096 12.0 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) RWD PF05773.22 ORY51534.1 - 4.4e-19 68.9 0.0 1.5e-18 67.1 0.0 1.9 2 0 0 2 2 2 1 RWD domain IBR PF01485.21 ORY51534.1 - 8.7e-15 54.7 28.7 1.2e-10 41.4 8.6 4.0 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain Chitin_synth_2 PF03142.15 ORY51535.1 - 5.3e-136 454.3 1.0 1.2e-135 453.2 1.0 1.4 1 1 0 1 1 1 1 Chitin synthase Glyco_tranf_2_3 PF13641.6 ORY51535.1 - 1.7e-15 57.6 0.0 2.4e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 ORY51535.1 - 7.3e-12 45.6 0.2 1.1e-11 45.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.6 ORY51535.1 - 8.2e-07 28.7 0.1 9.2e-06 25.2 0.1 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORY51535.1 - 0.001 18.9 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 RRM_1 PF00076.22 ORY51536.1 - 0.043 13.6 0.1 0.51 10.2 0.0 2.5 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OPT PF03169.15 ORY51537.1 - 7.1e-43 147.2 5.0 9.7e-43 146.7 5.0 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.15 ORY51538.1 - 1.1e-70 239.0 41.9 1.1e-68 232.5 41.9 2.1 1 1 0 1 1 1 1 OPT oligopeptide transporter protein PDZ_1 PF12812.7 ORY51539.1 - 2.4e-45 152.4 0.0 1.2e-30 105.3 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 ORY51539.1 - 4.7e-16 60.0 3.2 3.8e-10 40.9 1.7 3.8 3 1 0 3 3 3 2 Trypsin-like peptidase domain PDZ_2 PF13180.6 ORY51539.1 - 1.4e-13 51.0 0.0 6.3e-05 23.2 0.0 4.5 4 0 0 4 4 4 3 PDZ domain PDZ_6 PF17820.1 ORY51539.1 - 2.4e-12 46.5 0.0 2.4e-05 24.1 0.0 4.7 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.24 ORY51539.1 - 3.2e-06 27.4 0.0 0.029 14.7 0.0 3.8 4 0 0 4 4 4 2 PDZ domain Tricorn_PDZ PF14685.6 ORY51539.1 - 0.0015 18.4 0.1 0.25 11.3 0.0 3.4 4 0 0 4 4 4 1 Tricorn protease PDZ domain Na_Ca_ex PF01699.24 ORY51540.1 - 8e-43 146.0 31.3 1.1e-22 80.6 15.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF485 PF04341.12 ORY51540.1 - 0.18 11.7 2.7 0.29 11.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Na_Ca_ex PF01699.24 ORY51541.1 - 3e-43 147.4 32.2 2.1e-22 79.7 17.8 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein YrhC PF14143.6 ORY51541.1 - 0.024 14.7 0.8 0.024 14.7 0.8 2.7 3 0 0 3 3 3 0 YrhC-like protein SLATT_6 PF18169.1 ORY51541.1 - 0.12 11.9 0.1 0.34 10.5 0.1 1.8 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 CDP-OH_P_transf PF01066.21 ORY51541.1 - 0.22 12.3 0.3 0.22 12.3 0.3 3.9 3 1 0 3 3 3 0 CDP-alcohol phosphatidyltransferase Syndecan PF01034.20 ORY51541.1 - 8 6.5 0.0 8 6.5 0.0 3.8 5 0 0 5 5 5 0 Syndecan domain Na_Ca_ex PF01699.24 ORY51542.1 - 1.1e-40 139.0 34.0 8.1e-23 81.1 18.7 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein YrhC PF14143.6 ORY51542.1 - 0.52 10.4 3.2 0.56 10.3 0.7 2.5 2 0 0 2 2 2 0 YrhC-like protein Na_Ca_ex PF01699.24 ORY51543.1 - 4.9e-17 62.3 17.5 3.6e-15 56.2 12.5 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein PPR_2 PF13041.6 ORY51544.1 - 1.9e-12 47.1 0.0 0.00028 21.0 0.0 3.2 3 0 0 3 3 3 3 PPR repeat family PPR_3 PF13812.6 ORY51544.1 - 3.5e-08 33.4 0.0 0.067 13.3 0.0 3.1 2 1 1 3 3 3 3 Pentatricopeptide repeat domain PPR PF01535.20 ORY51544.1 - 1.7e-06 27.9 2.3 0.0031 17.6 0.0 3.5 4 0 0 4 4 4 2 PPR repeat PPR_long PF17177.4 ORY51544.1 - 0.00021 20.7 0.0 0.00029 20.3 0.0 1.2 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 ORY51544.1 - 0.026 14.2 0.0 38 4.1 0.0 3.5 3 0 0 3 3 3 0 PPR repeat TPR_2 PF07719.17 ORY51544.1 - 0.063 13.4 0.3 0.21 11.8 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3368 PF11848.8 ORY51544.1 - 0.12 12.2 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) TPR_8 PF13181.6 ORY51544.1 - 0.19 12.1 0.1 0.41 11.0 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Presenilin PF01080.17 ORY51546.1 - 9.9e-61 205.7 27.4 3.4e-47 161.1 4.9 2.9 2 1 1 3 3 3 2 Presenilin zf-MYND PF01753.18 ORY51546.1 - 5e-10 39.3 7.6 8.4e-10 38.6 7.6 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY51546.1 - 0.00031 21.0 5.8 0.00056 20.1 5.8 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding Orf78 PF06024.12 ORY51546.1 - 0.04 14.2 3.6 3.2 8.1 0.1 3.4 4 0 0 4 4 4 0 Orf78 (ac78) zf-HIT PF04438.16 ORY51546.1 - 0.38 10.7 6.5 0.69 9.8 6.5 1.5 1 0 0 1 1 1 0 HIT zinc finger Arm PF00514.23 ORY51547.1 - 2.7e-05 24.1 0.5 0.001 19.0 0.1 2.1 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 ORY51547.1 - 8.7e-05 22.5 2.0 0.081 13.2 0.3 2.7 1 1 2 3 3 3 3 HEAT repeat Cnd1 PF12717.7 ORY51547.1 - 0.00075 19.6 0.3 0.00086 19.4 0.3 1.1 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORY51547.1 - 0.00076 19.8 0.5 0.005 17.2 0.5 1.7 1 1 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.6 ORY51547.1 - 0.0025 18.3 0.6 0.24 12.0 0.2 2.1 2 0 0 2 2 2 1 HEAT-like repeat Adaptin_N PF01602.20 ORY51547.1 - 0.0043 15.7 0.2 0.0049 15.5 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region RTP1_C1 PF10363.9 ORY51547.1 - 0.017 15.3 0.0 0.019 15.1 0.0 1.0 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_PBS PF03130.16 ORY51547.1 - 0.025 15.2 0.1 0.036 14.7 0.1 1.3 1 0 0 1 1 1 0 PBS lyase HEAT-like repeat IFRD PF05004.13 ORY51547.1 - 0.036 13.2 0.2 0.038 13.1 0.2 1.0 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) Proteasom_PSMB PF10508.9 ORY51548.1 - 0.019 13.5 0.3 0.024 13.1 0.3 1.2 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.6 ORY51548.1 - 0.033 14.6 0.0 0.82 10.1 0.0 2.6 1 1 1 2 2 2 0 HEAT repeats Arm PF00514.23 ORY51548.1 - 0.061 13.4 1.1 0.62 10.2 0.2 2.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat CAP PF00188.26 ORY51550.1 - 3.8e-14 53.6 0.8 6.4e-14 52.9 0.8 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Mucin PF01456.17 ORY51550.1 - 0.016 15.2 28.8 0.033 14.2 28.8 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein NPR3 PF03666.13 ORY51550.1 - 0.039 12.8 0.3 0.046 12.5 0.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SprA-related PF12118.8 ORY51550.1 - 0.38 9.9 7.5 0.48 9.5 7.5 1.2 1 0 0 1 1 1 0 SprA-related family AJAP1_PANP_C PF15298.6 ORY51550.1 - 0.46 10.7 13.9 0.079 13.2 10.5 1.5 2 0 0 2 2 2 0 AJAP1/PANP C-terminus FSA_C PF10479.9 ORY51550.1 - 0.74 7.9 9.4 0.91 7.6 9.4 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus NUDE_C PF04880.13 ORY51550.1 - 3.5 8.1 13.7 5 7.6 13.7 1.2 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region DnaJ_CXXCXGXG PF00684.19 ORY51551.1 - 9.3e-07 29.1 43.1 0.0014 18.9 8.8 4.1 3 1 1 4 4 4 4 DnaJ central domain Pkinase PF00069.25 ORY51553.1 - 3.3e-54 184.0 0.0 1.3e-36 126.3 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY51553.1 - 3.8e-25 88.7 0.0 1.7e-20 73.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 ORY51553.1 - 0.00023 20.6 0.1 0.00051 19.5 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2373 PF10180.9 ORY51553.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Kinase-like PF14531.6 ORY51553.1 - 0.072 12.4 0.0 2.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Kinase-like SRP54 PF00448.22 ORY51553.1 - 0.19 11.4 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DnaB_2 PF07261.11 ORY51554.1 - 0.012 15.3 0.0 3.6 7.4 0.0 3.9 4 0 0 4 4 4 0 Replication initiation and membrane attachment Glycos_trans_3N PF02885.17 ORY51554.1 - 0.017 15.0 0.0 9.9 6.1 0.0 3.7 5 0 0 5 5 5 0 Glycosyl transferase family, helical bundle domain Kelch_6 PF13964.6 ORY51554.1 - 0.077 13.3 0.0 10 6.6 0.0 2.5 2 0 0 2 2 2 0 Kelch motif SGS PF05002.15 ORY51554.1 - 0.33 11.1 8.5 2.4 8.3 0.3 4.3 5 0 0 5 5 5 0 SGS domain BBL5 PF07289.11 ORY51555.1 - 9.2e-80 268.2 0.7 1e-79 268.0 0.7 1.0 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein Vps36_ESCRT-II PF11605.8 ORY51555.1 - 0.00017 21.7 0.3 0.0094 16.1 0.1 2.4 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 PH_TFIIH PF08567.11 ORY51555.1 - 0.00067 19.9 0.1 0.0038 17.5 0.0 2.1 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain Pyrid_ox_like PF16242.5 ORY51555.1 - 0.044 13.4 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like ELP6 PF09807.9 ORY51555.1 - 0.07 12.5 0.1 0.39 10.1 0.0 2.0 2 0 0 2 2 2 0 Elongation complex protein 6 DLH PF01738.18 ORY51556.1 - 1.3e-23 83.7 0.0 1.5e-23 83.5 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family UPF0227 PF05728.12 ORY51556.1 - 0.013 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) SnoaL_2 PF12680.7 ORY51557.1 - 0.00037 21.1 0.2 2 9.1 0.1 4.6 3 2 3 6 6 6 1 SnoaL-like domain DUF4440 PF14534.6 ORY51557.1 - 0.18 12.2 0.0 1.5e+02 2.9 0.0 4.4 1 1 4 6 6 6 0 Domain of unknown function (DUF4440) MVL PF12151.8 ORY51557.1 - 0.67 9.9 23.9 70 3.4 0.1 7.1 7 0 0 7 7 7 0 Mannan-binding protein CCAP PF11105.8 ORY51557.1 - 0.84 9.6 9.8 46 4.0 0.0 5.2 1 1 4 5 5 5 0 Arthropod cardioacceleratory peptide 2a S_2TMBeta PF18153.1 ORY51557.1 - 1.1 9.0 15.6 19 5.0 0.0 6.3 4 1 3 7 7 7 0 SMODS-associating 2TM, beta-strand rich effector domain FAD_binding_9 PF08021.11 ORY51557.1 - 3.2 8.0 12.6 27 5.0 0.1 5.2 1 1 4 6 6 6 0 Siderophore-interacting FAD-binding domain DUF1387 PF07139.11 ORY51560.1 - 0.76 9.4 11.4 1 9.0 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) zf-met PF12874.7 ORY51561.1 - 0.0045 17.3 0.9 4.6 7.8 0.0 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 ORY51561.1 - 0.27 12.2 15.3 0.44 11.5 0.6 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY51561.1 - 2.5 8.7 15.0 0.42 11.2 0.6 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type Amino_oxidase PF01593.24 ORY51562.1 - 0.0023 17.3 2.9 0.003 16.9 2.9 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Fib_alpha PF08702.10 ORY51562.1 - 0.0047 17.1 6.9 0.0047 17.1 6.9 2.5 2 1 0 2 2 2 1 Fibrinogen alpha/beta chain family Sec20 PF03908.13 ORY51562.1 - 0.0058 16.5 1.0 0.0058 16.5 1.0 2.9 3 0 0 3 3 3 1 Sec20 TolA_bind_tri PF16331.5 ORY51562.1 - 0.029 14.4 6.9 0.029 14.4 6.9 4.7 4 1 1 5 5 5 0 TolA binding protein trimerisation HIP1_clath_bdg PF16515.5 ORY51562.1 - 0.034 14.7 7.4 0.034 14.7 7.4 4.0 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc42p PF11544.8 ORY51562.1 - 0.089 12.8 6.2 0.17 11.9 4.0 2.6 1 1 0 1 1 1 0 Spindle pole body component Spc42p FlaC_arch PF05377.11 ORY51562.1 - 0.11 13.0 18.3 0.11 12.9 0.9 4.3 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) Sacchrp_dh_NADP PF03435.18 ORY51562.1 - 0.18 12.0 1.5 0.44 10.8 0.2 2.3 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Bacillus_HBL PF05791.11 ORY51562.1 - 0.34 10.7 5.8 1.6 8.6 0.1 2.9 1 1 3 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) KNOX2 PF03791.13 ORY51562.1 - 0.38 10.3 3.4 0.19 11.3 0.4 2.1 2 0 0 2 2 1 0 KNOX2 domain HrpB7 PF09486.10 ORY51562.1 - 0.61 10.5 29.5 0.83 10.0 4.2 2.5 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF4407 PF14362.6 ORY51562.1 - 0.75 9.1 18.4 0.91 8.8 17.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 ORY51562.1 - 1.2 6.5 30.6 3.7 4.9 30.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) ERM PF00769.19 ORY51562.1 - 1.6 8.5 42.7 0.63 9.8 28.7 2.6 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF1664 PF07889.12 ORY51562.1 - 1.6 8.8 17.5 0.082 13.0 3.7 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) GAS PF13851.6 ORY51562.1 - 2 7.7 38.7 1.4 8.2 10.3 3.6 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding USP8_interact PF08941.10 ORY51562.1 - 2.2 8.1 14.9 0.26 11.1 0.7 3.1 2 1 1 3 3 3 0 USP8 interacting Spc7 PF08317.11 ORY51562.1 - 3.1 6.6 33.7 0.099 11.5 18.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 ORY51562.1 - 3.5 7.8 34.4 3.4 7.8 10.0 3.3 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 ORY51562.1 - 4.5 7.5 34.8 2.8 8.2 7.1 3.3 1 1 2 3 3 2 0 TATA element modulatory factor 1 TATA binding SlyX PF04102.12 ORY51562.1 - 5.2 7.8 24.9 1.9 9.2 1.5 4.7 2 1 3 5 5 5 0 SlyX DUF1515 PF07439.11 ORY51562.1 - 6.7 6.8 13.2 4.6 7.3 4.7 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) Csm1_N PF18504.1 ORY51562.1 - 6.9 7.1 26.3 0.31 11.4 2.2 4.7 3 2 3 6 6 6 0 Csm1 N-terminal domain DUF5082 PF16888.5 ORY51562.1 - 7.6 6.8 18.2 0.18 12.1 5.7 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) Syntaxin-6_N PF09177.11 ORY51562.1 - 7.7 7.1 15.0 36 5.0 9.5 3.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TMEM51 PF15345.6 ORY51563.1 - 8.8 6.1 8.0 15 5.3 8.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 TRAM_LAG1_CLN8 PF03798.16 ORY51564.1 - 7.5e-15 55.2 5.0 9.1e-15 54.9 5.0 1.1 1 0 0 1 1 1 1 TLC domain MRP-L46 PF11788.8 ORY51565.1 - 1.5e-06 28.9 0.1 3.5e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 39S mitochondrial ribosomal protein L46 Thiolase_N PF00108.23 ORY51565.1 - 0.02 14.2 0.1 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 Thiolase, N-terminal domain NUDIX PF00293.28 ORY51565.1 - 0.024 14.6 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain Bystin PF05291.11 ORY51566.1 - 1.9e-134 447.6 0.2 3e-134 446.9 0.2 1.3 1 0 0 1 1 1 1 Bystin DUF1293 PF06950.11 ORY51566.1 - 0.094 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1293) IBB PF01749.20 ORY51566.1 - 0.39 11.2 4.0 0.43 11.1 2.7 1.8 1 1 0 1 1 1 0 Importin beta binding domain Proteasom_PSMB PF10508.9 ORY51567.1 - 6.9e-36 123.8 0.0 1e-35 123.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit DUF4490 PF14892.6 ORY51568.1 - 2.3e-18 66.2 0.2 2.6e-18 65.9 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4490) Ncstrn_small PF18266.1 ORY51569.1 - 6.1e-32 110.9 0.0 1.5e-31 109.7 0.0 1.7 1 0 0 1 1 1 1 Nicastrin small lobe Nicastrin PF05450.15 ORY51569.1 - 1.6e-29 103.1 1.5 5.5e-14 52.2 0.6 2.2 2 0 0 2 2 2 2 Nicastrin Peptidase_M28 PF04389.17 ORY51569.1 - 2.6e-07 30.5 0.1 1.1e-06 28.5 0.1 1.9 1 1 0 1 1 1 1 Peptidase family M28 Complex1_LYR_2 PF13233.6 ORY51570.1 - 4.8e-08 33.6 0.2 7.3e-08 33.1 0.2 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Evr1_Alr PF04777.13 ORY51571.1 - 3.7e-20 72.3 3.0 3.7e-20 72.3 3.0 2.3 2 1 0 2 2 2 1 Erv1 / Alr family Acetyltransf_13 PF13880.6 ORY51572.1 - 1.9e-29 101.4 0.0 4e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 ORY51572.1 - 1.7e-12 47.0 0.0 3.9e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.25 ORY51572.1 - 0.0005 20.3 0.0 0.0012 19.1 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 ORY51572.1 - 0.00073 19.9 0.0 0.002 18.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY51572.1 - 0.021 14.8 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ATG16 PF08614.11 ORY51572.1 - 0.2 11.9 3.4 0.28 11.4 3.4 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Spc7_N PF15402.6 ORY51572.1 - 0.45 8.7 7.4 0.56 8.4 7.4 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Pex14_N PF04695.13 ORY51572.1 - 0.98 10.1 8.8 1.5 9.5 8.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAP1 PF08601.10 ORY51572.1 - 2.9 7.5 10.0 21 4.7 10.9 1.8 2 0 0 2 2 2 0 Transcription factor PAP1 E1_DerP2_DerF2 PF02221.15 ORY51574.1 - 3.9e-05 24.1 0.0 5.7e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 ML domain Thermopsin PF05317.11 ORY51574.1 - 0.04 13.4 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Thermopsin E1_DerP2_DerF2 PF02221.15 ORY51575.1 - 0.00064 20.2 0.2 0.00099 19.5 0.2 1.4 1 1 0 1 1 1 1 ML domain Cons_hypoth698 PF03601.14 ORY51575.1 - 0.15 10.9 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 698 E1_DerP2_DerF2 PF02221.15 ORY51576.1 - 0.0012 19.3 0.1 0.0016 18.9 0.1 1.2 1 0 0 1 1 1 1 ML domain SMK-1 PF04802.15 ORY51577.1 - 2.3e-52 177.6 0.1 5e-52 176.5 0.1 1.6 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Trypan_PARP PF05887.11 ORY51577.1 - 0.12 12.4 5.0 0.26 11.2 5.0 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Rcd1 PF04078.13 ORY51577.1 - 0.73 9.1 3.2 2.6 7.3 0.1 2.7 3 0 0 3 3 3 0 Cell differentiation family, Rcd1-like EMP70 PF02990.16 ORY51578.1 - 1.6e-145 485.7 18.9 1.6e-145 485.7 18.9 1.6 2 0 0 2 2 2 1 Endomembrane protein 70 BNR PF02012.20 ORY51578.1 - 0.14 12.2 0.6 0.5 10.6 0.1 2.3 2 0 0 2 2 2 0 BNR/Asp-box repeat Ycf70 PF17382.2 ORY51578.1 - 1.3 9.5 3.7 34 4.9 0.0 3.6 3 1 0 3 3 3 0 Uncharacterized Ycf70-like IF3_N PF05198.16 ORY51579.1 - 5.8e-06 26.5 0.0 0.16 12.2 0.0 2.4 2 0 0 2 2 2 2 Translation initiation factor IF-3, N-terminal domain IF3_C PF00707.22 ORY51579.1 - 0.00029 20.8 0.2 0.00055 19.9 0.2 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain DUF4111 PF13427.6 ORY51579.1 - 0.0045 17.1 0.1 0.01 16.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4111) ADH_zinc_N PF00107.26 ORY51579.1 - 0.044 13.8 0.0 0.083 12.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AflR PF08493.10 ORY51579.1 - 0.56 9.6 7.3 1 8.8 7.3 1.4 1 0 0 1 1 1 0 Aflatoxin regulatory protein Methyltransf_16 PF10294.9 ORY51580.1 - 3.1e-27 95.4 0.1 5.9e-27 94.5 0.1 1.4 1 1 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 ORY51580.1 - 2e-06 27.4 0.2 2.5e-06 27.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 ORY51580.1 - 0.00023 21.0 0.0 0.00062 19.6 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.14 ORY51580.1 - 0.00032 20.3 0.1 0.00045 19.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 ORY51580.1 - 0.02 15.6 0.1 0.043 14.5 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 ORY51580.1 - 0.062 14.0 0.2 0.23 12.1 0.2 2.0 1 1 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 ORY51580.1 - 0.13 11.9 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_12 PF08242.12 ORY51580.1 - 0.14 12.9 0.0 0.27 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CAP PF00188.26 ORY51581.1 - 3.8e-15 56.8 0.8 5.2e-15 56.4 0.8 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 ORY51582.1 - 4.4e-14 53.4 0.1 5.5e-14 53.1 0.1 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family MIIP PF15734.5 ORY51583.1 - 6.5e-12 45.6 0.7 2.2e-11 43.8 0.7 1.7 1 1 0 1 1 1 1 Migration and invasion-inhibitory AAA_12 PF13087.6 ORY51585.1 - 7.7e-30 104.0 0.0 1.4e-28 99.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 ORY51585.1 - 1.3e-25 90.6 1.1 3.6e-15 56.4 0.0 2.6 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 ORY51585.1 - 2.4e-09 37.2 0.0 1.8e-06 27.8 0.0 2.5 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.6 ORY51585.1 - 2.2e-06 28.1 0.0 7.2e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 ORY51585.1 - 2.9e-05 24.1 0.0 4.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.29 ORY51585.1 - 0.092 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 ORY51585.1 - 0.16 11.3 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Gasdermin PF04598.12 ORY51586.1 - 0.038 13.4 0.1 0.053 12.9 0.1 1.1 1 0 0 1 1 1 0 Gasdermin pore forming domain AAA PF00004.29 ORY51588.1 - 1.4e-11 45.0 0.1 4.2e-09 36.9 0.1 2.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IQ PF00612.27 ORY51588.1 - 1.9e-05 24.1 0.4 5.6e-05 22.6 0.4 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif AAA_16 PF13191.6 ORY51588.1 - 0.00045 20.7 0.0 0.0015 19.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY51588.1 - 0.0091 16.3 0.0 0.026 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ORY51588.1 - 0.071 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 ORY51588.1 - 0.077 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 ORY51588.1 - 0.09 12.5 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 ORY51588.1 - 0.092 12.1 0.6 0.29 10.5 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 ORY51588.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 ORY51588.1 - 0.28 11.4 3.2 0.53 10.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain CAP PF00188.26 ORY51590.1 - 3e-29 102.4 2.6 1.8e-14 54.6 0.5 3.3 4 0 0 4 4 4 2 Cysteine-rich secretory protein family Bacillus_PapR PF05968.11 ORY51591.1 - 0.11 12.4 0.0 4.7 7.2 0.0 2.8 3 0 0 3 3 3 0 Bacillus PapR protein TPR_2 PF07719.17 ORY51592.1 - 3e-31 105.0 15.0 0.00016 21.5 0.0 10.2 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_1 PF00515.28 ORY51592.1 - 1e-28 97.9 21.5 6e-06 25.9 0.4 9.3 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_8 PF13181.6 ORY51592.1 - 2.9e-27 92.5 9.8 0.0021 18.2 0.2 9.2 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 ORY51592.1 - 5.5e-17 61.0 17.4 0.051 14.4 0.0 10.6 6 1 5 11 11 11 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY51592.1 - 4e-16 59.0 26.5 0.00013 22.1 0.1 7.6 4 3 2 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 ORY51592.1 - 5.2e-15 54.8 0.8 0.0018 17.9 0.0 7.0 5 1 3 8 8 8 4 TPR repeat TPR_19 PF14559.6 ORY51592.1 - 1.8e-14 54.0 18.8 0.0013 19.2 0.2 8.3 5 2 3 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 ORY51592.1 - 3.6e-13 49.9 12.7 0.00034 21.2 0.1 7.5 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 ORY51592.1 - 1.1e-12 48.0 18.0 0.13 12.6 0.1 8.7 7 2 1 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORY51592.1 - 4.5e-10 39.2 14.7 0.037 14.4 0.0 9.5 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY51592.1 - 5e-10 38.7 2.7 0.88 9.7 0.0 7.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 ORY51592.1 - 1.2e-07 31.9 19.8 0.035 14.7 0.1 9.4 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY51592.1 - 0.00011 22.3 7.6 2.2 8.5 0.0 5.4 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_21 PF09976.9 ORY51592.1 - 0.00028 20.7 9.1 0.17 11.6 0.1 4.5 4 1 1 5 5 5 1 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 ORY51592.1 - 0.00056 19.2 5.8 0.083 12.1 0.2 4.2 2 1 1 4 4 4 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 ORY51592.1 - 0.00058 19.5 3.7 0.047 13.3 0.1 3.4 3 0 0 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) BTAD PF03704.17 ORY51592.1 - 0.015 15.8 0.1 0.015 15.8 0.1 3.7 5 0 0 5 5 4 0 Bacterial transcriptional activator domain FAT PF02259.23 ORY51592.1 - 0.022 14.0 0.6 0.41 9.8 0.1 3.0 2 1 1 4 4 4 0 FAT domain Clathrin PF00637.20 ORY51592.1 - 0.059 13.3 0.0 0.85 9.5 0.0 2.8 2 0 0 2 2 2 0 Region in Clathrin and VPS SRP_TPR_like PF17004.5 ORY51592.1 - 0.11 12.5 1.9 0.59 10.2 0.1 2.8 4 0 0 4 4 3 0 Putative TPR-like repeat TPR_4 PF07721.14 ORY51592.1 - 0.13 12.9 17.2 6.8 7.6 0.1 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat Sel1 PF08238.12 ORY51592.1 - 0.63 10.8 2.8 18 6.2 0.2 3.8 4 0 0 4 4 3 0 Sel1 repeat TPR_20 PF14561.6 ORY51592.1 - 0.8 10.1 5.1 14 6.1 0.0 4.4 5 1 1 6 6 5 0 Tetratricopeptide repeat WD40 PF00400.32 ORY51593.1 - 1.7e-25 88.8 12.6 1.1e-08 35.6 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY51593.1 - 3.5e-13 49.7 0.2 0.00053 20.2 0.1 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY51593.1 - 0.0071 16.2 0.1 0.67 9.8 0.0 2.8 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 ORY51593.1 - 0.011 14.4 1.1 0.28 9.8 0.8 2.5 1 1 1 2 2 2 0 Nucleoporin Nup120/160 CCDC23 PF15674.5 ORY51594.1 - 0.0039 17.2 1.6 0.0075 16.3 1.6 1.5 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 23 Peptidase_A22B PF04258.13 ORY51596.1 - 8.5e-78 261.7 9.3 1.1e-77 261.4 9.3 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 ORY51596.1 - 1e-08 35.0 5.8 1e-08 35.0 5.8 1.8 3 0 0 3 3 3 1 Signal-peptide peptidase, presenilin aspartyl protease AAA PF00004.29 ORY51597.1 - 2.5e-98 325.6 0.0 1e-47 161.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY51597.1 - 7.3e-26 89.7 5.7 3.5e-13 49.1 0.4 3.1 2 1 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 ORY51597.1 - 5.2e-19 68.2 0.6 1.5e-18 66.8 0.6 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 ORY51597.1 - 3.5e-14 52.9 0.1 2.2e-05 24.3 0.0 3.4 2 2 1 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 ORY51597.1 - 3.7e-14 53.2 0.0 9.3e-07 29.1 0.0 3.5 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 ORY51597.1 - 2.4e-11 44.0 0.0 1.3e-05 25.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 ORY51597.1 - 2.8e-11 43.5 0.3 4.1e-05 23.6 0.1 4.1 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY51597.1 - 2.9e-11 44.0 0.0 0.0011 19.3 0.0 4.3 2 2 1 3 3 3 2 AAA ATPase domain CDC48_2 PF02933.17 ORY51597.1 - 4.3e-11 42.4 0.0 9.4e-11 41.3 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.13 ORY51597.1 - 3.4e-09 36.4 0.1 0.00037 19.8 0.1 2.8 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 ORY51597.1 - 9.8e-09 35.6 0.1 0.05 13.9 0.0 3.9 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.6 ORY51597.1 - 1.8e-07 31.8 0.2 0.023 15.2 0.0 3.1 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 ORY51597.1 - 2e-07 30.6 0.2 0.021 14.2 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 ORY51597.1 - 2.1e-07 31.3 0.0 0.0043 17.4 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 ORY51597.1 - 3.5e-07 30.3 0.0 0.022 14.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 ORY51597.1 - 4.9e-07 29.5 2.4 2.1 7.9 0.0 4.7 3 2 1 5 5 5 2 AAA domain ABC_tran PF00005.27 ORY51597.1 - 5.9e-07 30.1 0.0 0.0055 17.2 0.0 3.6 2 1 0 2 2 2 1 ABC transporter Vps4_C PF09336.10 ORY51597.1 - 1.1e-06 28.5 0.4 8.9e-06 25.6 0.1 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 ORY51597.1 - 1.7e-06 27.9 0.0 0.057 13.2 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein Parvo_NS1 PF01057.17 ORY51597.1 - 5.3e-06 25.7 0.1 0.036 13.2 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 ORY51597.1 - 1.2e-05 24.9 0.0 0.063 12.8 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region DUF815 PF05673.13 ORY51597.1 - 2e-05 23.9 0.0 0.01 15.0 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 ORY51597.1 - 2.1e-05 24.9 0.0 0.19 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.6 ORY51597.1 - 2.1e-05 25.0 0.4 0.63 10.5 0.0 3.7 4 0 0 4 4 3 2 AAA domain Bac_DnaA PF00308.18 ORY51597.1 - 2.6e-05 24.2 0.0 0.34 10.7 0.0 2.9 3 0 0 3 3 2 2 Bacterial dnaA protein ATPase_2 PF01637.18 ORY51597.1 - 3.7e-05 23.8 0.2 0.2 11.5 0.0 3.4 2 1 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_24 PF13479.6 ORY51597.1 - 3.9e-05 23.5 0.0 0.11 12.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 ORY51597.1 - 5.4e-05 23.0 0.0 0.4 10.4 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain Viral_helicase1 PF01443.18 ORY51597.1 - 6.1e-05 22.9 0.0 0.0032 17.2 0.0 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ATPase PF06745.13 ORY51597.1 - 7.9e-05 22.1 2.3 1.6 8.0 0.1 3.6 3 1 0 4 4 3 2 KaiC TsaE PF02367.17 ORY51597.1 - 0.00016 21.7 0.0 0.25 11.4 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 ORY51597.1 - 0.00027 21.0 0.0 0.089 12.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 ORY51597.1 - 0.00029 20.2 0.0 0.54 9.5 0.0 2.8 2 0 0 2 2 2 2 Zeta toxin NB-ARC PF00931.22 ORY51597.1 - 0.00033 19.9 0.0 0.14 11.3 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain PhoH PF02562.16 ORY51597.1 - 0.00048 19.7 0.1 1.1 8.7 0.1 2.6 2 0 0 2 2 2 2 PhoH-like protein DUF2075 PF09848.9 ORY51597.1 - 0.00072 18.9 0.0 0.3 10.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 ORY51597.1 - 0.00083 19.2 0.0 1.6 8.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 ORY51597.1 - 0.00087 19.2 0.1 0.3 11.0 0.0 2.8 2 1 0 2 2 2 1 NACHT domain AAA_11 PF13086.6 ORY51597.1 - 0.0012 18.7 0.5 1.6 8.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 ORY51597.1 - 0.0045 16.9 0.0 0.51 10.2 0.0 2.5 2 1 0 2 2 2 1 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 ORY51597.1 - 0.0066 16.6 0.0 6.8 6.8 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Cytidylate_kin2 PF13189.6 ORY51597.1 - 0.0092 16.1 0.0 1.4 9.0 0.0 2.7 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_19 PF13245.6 ORY51597.1 - 0.011 16.1 1.2 10 6.4 0.2 3.6 3 1 1 4 4 4 0 AAA domain NTPase_1 PF03266.15 ORY51597.1 - 0.022 14.7 1.1 5 7.0 0.0 3.9 4 0 0 4 4 4 0 NTPase AAA_30 PF13604.6 ORY51597.1 - 0.042 13.6 0.2 5.7 6.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 ORY51597.1 - 0.051 13.7 0.1 9.3 6.3 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase Cytidylate_kin PF02224.18 ORY51597.1 - 0.052 13.3 0.0 12 5.5 0.0 2.8 2 0 0 2 2 2 0 Cytidylate kinase T2SSE PF00437.20 ORY51597.1 - 0.13 11.3 0.0 11 4.9 0.0 2.9 2 1 1 3 3 3 0 Type II/IV secretion system protein Adeno_IVa2 PF02456.15 ORY51597.1 - 0.17 10.7 0.0 3.2 6.5 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein Zot PF05707.12 ORY51597.1 - 0.17 11.5 0.0 2.2 7.9 0.0 2.5 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Bromodomain PF00439.25 ORY51599.1 - 4.1e-17 62.0 0.1 6.9e-17 61.3 0.1 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 ORY51599.1 - 3.4e-07 30.5 0.0 6.4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY51599.1 - 0.00022 21.2 0.0 0.00038 20.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY51599.1 - 0.0011 19.3 0.1 0.0021 18.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 ORY51599.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein HCNGP PF07818.13 ORY51600.1 - 3.2e-17 63.0 0.0 7.3e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 HCNGP-like protein zf_CCCH_4 PF18345.1 ORY51600.1 - 3.4e-13 49.2 34.7 2.5e-05 24.2 4.1 4.6 4 0 0 4 4 4 4 Zinc finger domain zf-CCCH_4 PF18044.1 ORY51600.1 - 5.8e-13 48.3 32.1 9.1e-05 22.2 2.9 4.6 4 0 0 4 4 4 4 CCCH-type zinc finger zf-CCCH PF00642.24 ORY51600.1 - 2.3e-09 36.9 27.3 3.7e-05 23.5 2.7 4.6 4 0 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.6 ORY51600.1 - 9.2e-07 28.7 9.0 9.2e-07 28.7 9.0 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 ORY51600.1 - 6.2e-06 26.5 10.0 6.2e-06 26.5 10.0 3.7 4 0 0 4 4 2 1 Ring finger domain Torus PF16131.5 ORY51600.1 - 9.8e-06 26.2 22.9 0.019 15.7 1.1 4.5 3 1 1 4 4 4 3 Torus domain zf-C3HC4 PF00097.25 ORY51600.1 - 1.8e-05 24.5 8.7 1.8e-05 24.5 8.7 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 ORY51600.1 - 0.0005 19.9 9.0 0.0005 19.9 9.0 2.9 2 1 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 ORY51600.1 - 0.00053 20.0 5.6 0.00067 19.6 2.3 2.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-CCCH_2 PF14608.6 ORY51600.1 - 1.5 9.4 27.4 2.1 8.9 2.8 4.9 4 1 0 4 4 4 0 RNA-binding, Nab2-type zinc finger zf-C3HC4_4 PF15227.6 ORY51600.1 - 4.8 7.4 17.0 0.042 14.0 6.3 2.8 3 0 0 3 3 2 0 zinc finger of C3HC4-type, RING zf-CCCH_3 PF15663.5 ORY51600.1 - 9.9 6.4 22.5 0.49 10.6 4.8 3.9 3 1 0 3 3 3 0 Zinc-finger containing family Nop16 PF09420.10 ORY51604.1 - 4.7e-23 82.3 2.3 8.5e-23 81.5 2.3 1.4 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 CENP-S PF15630.6 ORY51605.1 - 2.8e-24 85.3 0.8 3.4e-24 85.0 0.8 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORY51605.1 - 7.5e-08 32.5 0.2 9.1e-08 32.2 0.2 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold ComGG PF14173.6 ORY51605.1 - 0.00097 19.5 0.0 0.0015 18.9 0.0 1.2 1 0 0 1 1 1 1 ComG operon protein 7 TFIID-18kDa PF02269.16 ORY51605.1 - 0.054 13.5 0.1 0.064 13.3 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit TFIID-31kDa PF02291.15 ORY51605.1 - 0.1 12.7 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CBS PF00571.28 ORY51606.1 - 1.3e-19 70.4 0.6 1.6e-06 28.5 0.0 5.0 4 1 0 4 4 4 4 CBS domain NIF3 PF01784.18 ORY51607.1 - 2e-65 220.8 0.0 2.5e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Podoplanin PF05808.11 ORY51609.1 - 0.00019 21.6 0.8 0.00023 21.3 0.1 1.4 2 0 0 2 2 2 1 Podoplanin PTP_tm PF18861.1 ORY51609.1 - 0.00048 20.2 0.1 0.00076 19.5 0.1 1.3 1 0 0 1 1 1 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J Phage_Coat_B PF05356.11 ORY51609.1 - 0.16 11.9 0.6 0.43 10.5 0.1 1.9 2 0 0 2 2 2 0 Phage Coat protein B LapA_dom PF06305.11 ORY51609.1 - 0.24 11.2 1.4 0.51 10.2 1.4 1.5 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Med22 PF06179.12 ORY51610.1 - 5.6e-11 42.6 0.3 6.6e-11 42.4 0.3 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Adaptin_N PF01602.20 ORY51611.1 - 4.3e-139 464.4 13.9 5.2e-139 464.2 13.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 ORY51611.1 - 1.2e-58 197.7 2.2 5.3e-56 189.1 0.4 2.7 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 ORY51611.1 - 1.6e-18 66.8 4.3 3.2e-06 27.4 0.0 5.7 2 2 3 5 5 5 5 HEAT repeats HEAT PF02985.22 ORY51611.1 - 5.5e-12 44.8 4.0 0.004 17.3 0.0 6.7 6 0 0 6 6 6 2 HEAT repeat Alpha_adaptinC2 PF02883.20 ORY51611.1 - 1.1e-07 32.1 0.1 3.3e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain RTP1_C1 PF10363.9 ORY51611.1 - 0.00012 22.2 6.8 5.6 7.2 0.0 5.0 2 2 3 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 ORY51611.1 - 0.0027 17.0 2.5 0.0071 15.6 0.1 2.6 2 2 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain TIP120 PF08623.10 ORY51611.1 - 0.0028 17.5 6.4 2.4 7.9 0.3 4.5 4 1 0 4 4 4 2 TATA-binding protein interacting (TIP20) CLASP_N PF12348.8 ORY51611.1 - 0.0038 16.8 0.9 8.4 5.9 0.0 3.8 3 1 1 4 4 4 1 CLASP N terminal HEAT_EZ PF13513.6 ORY51611.1 - 0.004 17.6 6.5 16 6.2 0.0 5.8 5 2 2 7 7 6 0 HEAT-like repeat Arm PF00514.23 ORY51611.1 - 0.0047 16.9 6.6 3 8.0 0.0 5.6 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Sec7_N PF12783.7 ORY51611.1 - 0.59 10.0 8.8 0.28 11.1 0.7 3.4 3 1 1 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal WD40 PF00400.32 ORY51613.1 - 5.9e-14 52.2 1.6 0.00023 21.9 0.0 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY51613.1 - 5.9e-06 26.5 0.0 0.53 10.6 0.0 4.4 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 ORY51613.1 - 0.011 16.2 9.1 0.013 16.0 0.7 3.8 4 0 0 4 4 4 0 PQQ-like domain PQQ_2 PF13360.6 ORY51613.1 - 0.068 12.8 0.2 1.3 8.6 0.2 2.2 1 1 0 1 1 1 0 PQQ-like domain Syntaxin_2 PF14523.6 ORY51614.1 - 6e-26 90.8 1.0 6e-26 90.8 1.0 2.8 2 1 0 3 3 3 1 Syntaxin-like protein SNARE PF05739.19 ORY51614.1 - 3.3e-10 39.8 0.2 3.3e-10 39.8 0.2 2.6 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 ORY51614.1 - 0.0013 18.4 13.7 0.0038 16.9 13.8 1.7 1 1 0 1 1 1 1 Syntaxin DUF883 PF05957.13 ORY51614.1 - 0.0055 17.3 3.7 0.99 10.0 2.5 2.7 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 ORY51614.1 - 0.22 12.1 1.4 1.8 9.2 1.4 2.3 1 1 0 1 1 1 0 YtxH-like protein FTO_NTD PF12933.7 ORY51614.1 - 0.3 10.3 4.8 0.45 9.7 4.8 1.3 1 0 0 1 1 1 0 FTO catalytic domain V_ATPase_I PF01496.19 ORY51614.1 - 4.7 5.0 8.8 6.3 4.6 8.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family dDENN PF03455.19 ORY51615.1 - 0.023 14.7 0.3 1.2 9.2 0.1 2.3 1 1 1 2 2 2 0 dDENN domain Mrx7 PF10906.8 ORY51615.1 - 0.079 13.2 0.8 0.17 12.1 0.8 1.7 1 1 0 1 1 1 0 MIOREX complex component 7 HSP90 PF00183.18 ORY51616.1 - 3.1e-237 788.5 33.8 4.2e-237 788.1 33.8 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 ORY51616.1 - 9.4e-15 55.1 0.1 1.8e-14 54.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 ORY51616.1 - 3.3e-09 36.7 0.1 1.2e-08 34.9 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_S10 PF00450.22 ORY51616.1 - 0.092 12.1 0.0 0.092 12.1 0.0 2.0 3 0 0 3 3 3 0 Serine carboxypeptidase LOH1CR12 PF10158.9 ORY51616.1 - 0.097 12.7 1.4 0.3 11.1 0.2 2.4 2 0 0 2 2 2 0 Tumour suppressor protein DUF4407 PF14362.6 ORY51616.1 - 7.4 5.8 6.5 6.2 6.1 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GATA PF00320.27 ORY51617.1 - 6e-14 51.4 4.7 9.2e-14 50.8 4.7 1.3 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 ORY51617.1 - 0.014 14.9 0.9 0.029 13.9 0.9 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding RNA_pol_Rpb1_R PF05001.13 ORY51618.1 - 0.0055 17.0 12.8 0.0055 17.0 12.8 9.0 6 2 5 11 11 11 7 RNA polymerase Rpb1 C-terminal repeat LKAAEAR PF15478.6 ORY51619.1 - 2.3e-09 37.7 4.3 3.4e-09 37.1 4.3 1.2 1 0 0 1 1 1 1 Family of unknown function with LKAAEAR motif RmlD_sub_bind PF04321.17 ORY51620.1 - 4e-64 216.5 0.0 5e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 ORY51620.1 - 2.6e-21 76.2 0.0 3.5e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY51620.1 - 2.4e-06 26.9 1.0 0.00026 20.2 0.4 3.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 ORY51620.1 - 1.7e-05 24.1 0.0 0.0026 17.0 0.0 2.7 1 1 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 ORY51620.1 - 3.7e-05 23.3 0.0 0.00016 21.2 0.0 2.0 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 ORY51620.1 - 4.8e-05 22.5 1.0 0.00086 18.4 1.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 ORY51620.1 - 0.0074 15.9 0.0 3.7 7.0 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family KR PF08659.10 ORY51620.1 - 0.031 14.2 1.5 1.9 8.3 0.3 2.7 2 1 1 3 3 3 0 KR domain Peptidase_C2 PF00648.21 ORY51621.1 - 1.4e-59 201.6 0.0 4.2e-59 200.0 0.0 1.7 1 1 0 1 1 1 1 Calpain family cysteine protease zf-GRF PF06839.12 ORY51621.1 - 9.9e-13 48.0 5.1 2e-12 47.0 5.1 1.5 1 0 0 1 1 1 1 GRF zinc finger UBM PF14377.6 ORY51621.1 - 0.0011 18.4 1.0 0.13 11.7 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin binding region Glyco_hydro_63 PF03200.16 ORY51623.1 - 1.6e-09 37.1 3.9 2.4e-05 23.3 0.1 4.3 5 1 0 5 5 5 2 Glycosyl hydrolase family 63 C-terminal domain DUF2335 PF10097.9 ORY51623.1 - 0.15 12.1 0.0 0.6 10.1 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2335) Peptidase_M3 PF01432.20 ORY51624.1 - 1.5e-112 377.2 0.2 1.9e-112 376.8 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M3 Acetyltransf_2 PF00797.17 ORY51625.1 - 7.4e-34 117.6 0.0 1e-33 117.2 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase DUF4261 PF14080.6 ORY51625.1 - 0.034 14.3 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4261) Tox-PLDMTX PF15645.6 ORY51625.1 - 0.062 13.6 0.0 0.097 12.9 0.0 1.3 1 0 0 1 1 1 0 Dermonecrotoxin of the Papain-like fold RIH_assoc PF08454.11 ORY51626.1 - 0.0004 20.2 6.0 0.038 13.8 0.0 4.4 4 1 0 5 5 5 2 RyR and IP3R Homology associated FAS_N PF17828.1 ORY51626.1 - 0.063 13.3 0.1 0.23 11.4 0.1 2.0 1 0 0 1 1 1 0 N-terminal domain in fatty acid synthase subunit beta Mt_ATP-synt_D PF05873.12 ORY51627.1 - 7e-18 64.9 2.2 8.4e-18 64.7 2.2 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) HTH_43 PF09904.9 ORY51627.1 - 0.093 12.7 0.0 0.68 9.9 0.0 2.1 2 1 0 2 2 2 0 Winged helix-turn helix Spc29 PF17082.5 ORY51627.1 - 0.12 12.2 0.3 0.15 11.9 0.3 1.2 1 1 0 1 1 1 0 Spindle Pole Component 29 Spectrin PF00435.21 ORY51627.1 - 0.31 11.6 3.3 2.5 8.6 0.0 2.4 2 1 1 3 3 3 0 Spectrin repeat PDEase_I PF00233.19 ORY51628.1 - 1.9e-69 234.0 2.8 1.9e-69 234.0 2.8 2.2 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase GAF PF01590.26 ORY51628.1 - 2.4e-26 92.9 0.0 8.2e-12 45.9 0.0 2.5 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 ORY51628.1 - 7.6e-12 45.7 0.0 7.3e-05 23.1 0.0 3.5 2 1 0 2 2 2 2 GAF domain GAF_3 PF13492.6 ORY51628.1 - 2e-05 24.9 0.0 0.017 15.4 0.0 3.0 3 0 0 3 3 3 2 GAF domain Kinesin PF00225.23 ORY51630.1 - 6.1e-80 268.6 0.1 2.7e-40 138.3 3.6 2.2 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 ORY51630.1 - 5.3e-25 88.1 0.0 1e-24 87.2 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Kinesin_assoc PF16183.5 ORY51630.1 - 7.5e-23 81.6 4.3 1.9e-20 73.7 2.6 3.2 2 1 0 2 2 2 1 Kinesin-associated DUF3694 PF12473.8 ORY51630.1 - 5.5e-22 79.1 0.0 1.5e-21 77.6 0.0 1.7 1 0 0 1 1 1 1 Kinesin protein PH PF00169.29 ORY51630.1 - 1.2e-06 28.9 0.0 3.8e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 PH domain FHA PF00498.26 ORY51630.1 - 0.00016 22.0 0.0 0.0011 19.3 0.0 2.5 2 0 0 2 2 2 1 FHA domain ThiS-like PF14453.6 ORY51630.1 - 0.0027 17.7 0.0 0.0074 16.3 0.0 1.7 1 0 0 1 1 1 1 ThiS-like ubiquitin PhetRS_B1 PF18262.1 ORY51630.1 - 0.051 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain PH_9 PF15410.6 ORY51630.1 - 0.081 13.3 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Tetraspanin PF00335.20 ORY51631.1 - 1.6e-20 73.8 8.5 1.4e-19 70.7 8.5 1.9 1 1 0 1 1 1 1 Tetraspanin family G-alpha PF00503.20 ORY51632.1 - 4e-106 355.2 6.0 4.6e-106 355.0 6.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY51632.1 - 1e-12 47.9 6.2 5.7e-09 35.7 0.2 3.3 3 1 0 3 3 3 2 ADP-ribosylation factor family Roc PF08477.13 ORY51632.1 - 5.7e-05 23.3 5.4 0.13 12.5 0.2 3.8 3 1 1 4 4 4 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 ORY51632.1 - 0.00036 20.0 1.3 0.047 13.0 0.2 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 ORY51632.1 - 0.062 13.0 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY51632.1 - 0.062 13.4 0.1 5.5 7.1 0.0 2.8 2 1 1 3 3 3 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 ORY51632.1 - 0.1 12.1 1.5 1.5 8.3 0.2 2.6 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.18 ORY51632.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.20 ORY51633.1 - 1.6e-103 346.6 1.2 2e-103 346.3 1.2 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY51633.1 - 1.6e-17 63.5 2.2 5.4e-14 52.0 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 ORY51633.1 - 5.5e-07 29.8 0.4 0.0028 17.9 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 ORY51633.1 - 0.00054 19.4 1.4 0.0092 15.4 0.2 2.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Ras PF00071.22 ORY51633.1 - 0.062 12.9 0.6 9.1 5.9 0.1 2.4 2 0 0 2 2 2 0 Ras family FtsK_SpoIIIE PF01580.18 ORY51633.1 - 0.071 12.5 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DAP3 PF10236.9 ORY51633.1 - 0.088 12.0 1.3 0.13 11.4 0.3 1.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Rad17 PF03215.15 ORY51633.1 - 0.14 12.1 1.7 0.12 12.2 0.3 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain GTP_EFTU PF00009.27 ORY51633.1 - 0.16 11.5 0.4 2.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain WD40 PF00400.32 ORY51634.1 - 5.8e-32 109.2 9.5 8.7e-08 32.7 0.3 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY51634.1 - 2.3e-18 66.3 0.2 0.00061 20.0 0.0 6.1 2 2 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 ORY51634.1 - 7.8e-16 57.4 0.2 1.5e-15 56.5 0.2 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 ORY51634.1 - 2e-10 40.2 4.1 0.0071 15.3 0.1 5.1 2 1 3 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 ORY51634.1 - 8e-07 28.1 0.1 0.035 12.8 0.0 3.1 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 ORY51634.1 - 0.017 13.9 0.0 1.4 7.6 0.0 3.0 1 1 2 3 3 3 0 Nup133 N terminal like PALB2_WD40 PF16756.5 ORY51634.1 - 0.13 11.2 0.3 6.3 5.6 0.0 2.6 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain PD40 PF07676.12 ORY51634.1 - 0.16 11.9 0.1 6.9 6.7 0.0 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat NUP214 PF16755.5 ORY51634.1 - 0.35 10.1 3.2 0.27 10.4 1.6 1.6 2 0 0 2 2 2 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 Proteasome PF00227.26 ORY51635.1 - 6.4e-46 156.2 0.2 9.1e-46 155.7 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 ORY51635.1 - 1.9e-13 49.8 0.2 3.2e-13 49.1 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Dehydratase_MU PF02288.15 ORY51635.1 - 0.02 14.8 0.7 6.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Dehydratase medium subunit MWFE PF15879.5 ORY51636.1 - 1.8e-16 60.0 0.0 2.3e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit Laminin_II PF06009.12 ORY51637.1 - 0.00051 20.1 0.2 0.00063 19.8 0.2 1.3 1 0 0 1 1 1 1 Laminin Domain II BORCS6 PF10157.9 ORY51637.1 - 0.0092 16.2 0.3 0.011 16.0 0.3 1.1 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 6 ApoLp-III PF07464.11 ORY51637.1 - 0.03 14.4 1.4 0.062 13.4 0.6 1.8 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF948 PF06103.11 ORY51637.1 - 0.14 12.4 1.6 0.29 11.4 0.8 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) cNMP_binding PF00027.29 ORY51639.1 - 3.5e-16 59.0 0.1 2.5e-05 24.2 0.0 4.1 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain CENP-B_dimeris PF09026.10 ORY51639.1 - 2.9 8.4 10.5 8.6 6.8 10.5 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FUN14 PF04930.15 ORY51641.1 - 5.5e-21 74.8 1.1 6.6e-21 74.5 1.1 1.1 1 0 0 1 1 1 1 FUN14 family EF-hand_5 PF13202.6 ORY51641.1 - 0.0052 16.2 0.4 0.011 15.2 0.4 1.5 1 0 0 1 1 1 1 EF hand Dockerin_1 PF00404.18 ORY51641.1 - 0.0054 16.9 0.2 0.0079 16.4 0.2 1.2 1 0 0 1 1 1 1 Dockerin type I domain EF-hand_8 PF13833.6 ORY51641.1 - 0.012 15.4 0.0 0.071 13.0 0.1 2.0 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 ORY51641.1 - 0.017 14.7 0.1 0.033 13.7 0.1 1.6 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 ORY51641.1 - 0.05 13.5 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 EF-hand domain Myb_DNA-binding PF00249.31 ORY51644.1 - 1.6e-09 37.8 1.8 3.3e-06 27.2 0.2 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY51644.1 - 1.2e-06 28.7 1.1 2.1e-05 24.7 0.1 3.1 3 1 1 4 4 4 1 Myb-like DNA-binding domain Rap1_C PF11626.8 ORY51644.1 - 0.0021 18.1 0.5 0.6 10.2 0.1 2.4 2 0 0 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF5345 PF17280.2 ORY51645.1 - 0.07 13.1 0.3 0.16 12.0 0.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5345) SPT6_acidic PF14632.6 ORY51645.1 - 0.14 12.8 0.4 0.14 12.8 0.4 2.6 2 1 1 3 3 3 0 Acidic N-terminal SPT6 Polysacc_deac_1 PF01522.21 ORY51647.1 - 7.7e-32 109.8 0.0 1e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase PGM_PMM_I PF02878.16 ORY51647.1 - 0.041 13.6 0.1 0.084 12.6 0.1 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I DUF2334 PF10096.9 ORY51647.1 - 0.12 12.0 0.1 0.3 10.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) WD40 PF00400.32 ORY51648.1 - 0.00023 21.9 1.2 0.0058 17.5 0.2 2.7 3 0 0 3 3 3 1 WD domain, G-beta repeat Radial_spoke PF04712.12 ORY51649.1 - 1.9e-19 70.0 2.5 4.8e-07 29.1 0.0 3.5 1 1 3 4 4 4 3 Radial spokehead-like protein DUF5463 PF17551.2 ORY51650.1 - 0.019 14.8 0.4 0.042 13.7 0.4 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5463) CDC45 PF02724.14 ORY51650.1 - 4 5.6 15.9 5.5 5.2 15.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.11 ORY51650.1 - 7.3 5.3 8.7 11 4.8 8.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 NUDIX_2 PF13869.6 ORY51652.1 - 2.5e-71 239.2 0.0 2.8e-71 239.0 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase NUDIX PF00293.28 ORY51652.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.4 1 1 0 1 1 1 0 NUDIX domain TFIIF_beta PF02270.15 ORY51653.1 - 7.4e-22 77.3 0.2 1.5e-21 76.2 0.2 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 ORY51653.1 - 4.5e-14 53.3 0.3 8.9e-14 52.3 0.3 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit N-terminus DUF2673 PF10880.8 ORY51653.1 - 1.4 9.1 6.2 0.91 9.7 2.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) BLOC1S3 PF15753.5 ORY51653.1 - 3.3 7.8 6.9 0.53 10.4 2.5 1.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 KBP_C PF12309.8 ORY51654.1 - 4.3e-41 141.6 0.0 1.5e-40 139.9 0.0 1.8 1 1 0 1 1 1 1 KIF-1 binding protein C terminal HD_4 PF13328.6 ORY51655.1 - 5.4e-21 75.0 0.3 7.6e-21 74.5 0.3 1.2 1 0 0 1 1 1 1 HD domain HD PF01966.22 ORY51655.1 - 7.5e-07 29.4 1.0 1.3e-06 28.6 1.0 1.4 1 0 0 1 1 1 1 HD domain UPF0147 PF03685.13 ORY51655.1 - 0.038 14.0 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Arabinose_Isome PF02610.15 ORY51655.1 - 0.048 12.9 0.1 0.06 12.5 0.1 1.2 1 0 0 1 1 1 0 L-arabinose isomerase OpuAC PF04069.12 ORY51656.1 - 4.7e-10 39.5 0.0 5.6e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 Substrate binding domain of ABC-type glycine betaine transport system Nup188 PF10487.9 ORY51657.1 - 1.5e-62 211.9 0.2 5e-62 210.1 0.0 1.8 2 0 0 2 2 2 1 Nucleoporin subcomplex protein binding to Pom34 Hist_deacetyl PF00850.19 ORY51658.1 - 3.1e-80 269.9 0.5 4.2e-80 269.5 0.1 1.4 2 0 0 2 2 2 1 Histone deacetylase domain API5 PF05918.11 ORY51658.1 - 0.34 9.7 1.8 0.72 8.6 1.6 1.4 1 1 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) PRR20 PF15708.5 ORY51658.1 - 0.73 9.7 3.7 1.2 9.0 3.7 1.3 1 0 0 1 1 1 0 Proline-rich protein family 20 MFS_MOT1 PF16983.5 ORY51662.1 - 1.7e-53 179.8 29.1 8e-32 109.9 4.8 3.1 3 0 0 3 3 3 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 ORY51662.1 - 6.1e-05 21.9 2.6 6.1e-05 21.9 2.6 2.7 2 2 1 3 3 3 1 Sulfate permease family TctB PF07331.11 ORY51662.1 - 0.0021 18.3 2.8 0.0021 18.3 2.8 3.9 1 1 2 3 3 3 1 Tripartite tricarboxylate transporter TctB family TLD PF07534.16 ORY51663.1 - 7.3e-36 123.4 0.0 8.1e-36 123.3 0.0 1.0 1 0 0 1 1 1 1 TLD G-alpha PF00503.20 ORY51665.1 - 4.5e-106 355.0 0.0 5.2e-106 354.8 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY51665.1 - 5.9e-18 64.9 3.1 3.1e-14 52.8 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 ORY51665.1 - 2.5e-06 27.7 0.3 0.0014 18.8 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 ORY51665.1 - 0.00027 20.4 0.4 0.0069 15.8 0.1 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Ras PF00071.22 ORY51665.1 - 0.28 10.7 1.5 11 5.5 0.1 2.3 2 0 0 2 2 2 0 Ras family G-alpha PF00503.20 ORY51666.1 - 3.6e-113 378.3 0.1 4.1e-113 378.1 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY51666.1 - 5.4e-18 65.1 4.0 4.2e-14 52.4 0.7 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 ORY51666.1 - 1.5e-06 28.4 0.6 0.0069 16.6 0.1 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 ORY51666.1 - 0.00016 21.1 0.8 0.0038 16.6 0.2 2.3 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Ras PF00071.22 ORY51666.1 - 0.008 15.8 1.3 3.3 7.3 0.3 2.5 2 0 0 2 2 2 2 Ras family TniB PF05621.11 ORY51666.1 - 0.05 13.0 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ComFB PF10719.9 ORY51666.1 - 0.05 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 Late competence development protein ComFB GTP_EFTU PF00009.27 ORY51666.1 - 0.074 12.6 1.6 0.56 9.7 0.4 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 ORY51666.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.20 ORY51667.1 - 2.8e-19 69.5 3.2 3.3e-19 69.3 3.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit DUF4771 PF15995.5 ORY51667.1 - 0.074 13.3 0.3 0.15 12.4 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4771) Arf PF00025.21 ORY51667.1 - 0.3 10.5 4.2 0.1 12.0 0.9 1.9 2 1 1 3 3 3 0 ADP-ribosylation factor family G-alpha PF00503.20 ORY51668.1 - 1.4e-42 146.2 0.1 1.6e-42 146.0 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY51668.1 - 1.9e-11 43.7 0.1 2.5e-11 43.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORY51668.1 - 0.0083 16.3 0.0 0.01 16.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 ORY51668.1 - 0.0093 15.3 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 ORY51669.1 - 4e-83 279.5 3.2 4.6e-83 279.3 3.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY51669.1 - 1.2e-13 50.9 0.1 1.9e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORY51669.1 - 0.00045 20.4 0.0 0.00099 19.3 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 ORY51670.1 - 6.7e-99 331.4 0.0 2.2e-98 329.7 0.0 1.7 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY51670.1 - 2.5e-07 30.3 0.6 0.0033 16.9 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY51670.1 - 0.052 12.9 0.1 3.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.6 ORY51670.1 - 0.078 12.7 2.1 0.28 11.0 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Tti2 PF10521.9 ORY51671.1 - 7e-13 48.8 10.3 9e-12 45.1 1.1 2.8 2 1 1 3 3 3 2 Tti2 family Lipoprotein_19 PF13617.6 ORY51671.1 - 0.61 9.9 1.6 0.81 9.5 0.1 1.9 2 0 0 2 2 2 0 YnbE-like lipoprotein Tmemb_185A PF10269.9 ORY51671.1 - 2.3 7.8 6.2 13 5.4 0.7 2.5 1 1 1 2 2 2 0 Transmembrane Fragile-X-F protein zf-C2H2_2 PF12756.7 ORY51672.1 - 1.6e-26 92.5 1.0 1.6e-14 54.0 0.5 3.5 4 0 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 ORY51672.1 - 0.057 14.3 13.6 0.12 13.2 0.1 4.8 5 0 0 5 5 5 0 C2H2-type zinc finger ORC_WH_C PF18137.1 ORY51672.1 - 0.19 11.8 2.0 0.56 10.3 0.1 2.3 2 1 0 2 2 2 0 Origin recognition complex winged helix C-terminal zf-BED PF02892.15 ORY51672.1 - 0.24 11.4 0.1 0.24 11.4 0.1 2.6 4 0 0 4 4 4 0 BED zinc finger CENP-B_dimeris PF09026.10 ORY51672.1 - 0.24 11.8 0.0 0.24 11.8 0.0 3.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain TFIIB PF00382.19 ORY51673.1 - 4.8e-25 87.4 0.1 3.9e-15 55.6 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 ORY51673.1 - 2.1e-11 43.1 0.6 3.8e-11 42.3 0.6 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 ORY51673.1 - 0.032 14.0 0.1 0.055 13.2 0.1 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain NDK PF00334.19 ORY51673.1 - 0.077 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Nucleoside diphosphate kinase RB_B PF01857.20 ORY51673.1 - 0.16 12.0 0.1 0.58 10.2 0.0 1.8 2 0 0 2 2 2 0 Retinoblastoma-associated protein B domain PAR1 PF06521.11 ORY51673.1 - 0.43 10.2 3.2 9.1 5.9 0.1 2.7 3 1 0 3 3 3 0 PAR1 protein zf-LITAF-like PF10601.9 ORY51673.1 - 1.2 9.5 3.4 32 4.9 0.8 3.3 3 1 1 4 4 4 0 LITAF-like zinc ribbon domain zf-ribbon_3 PF13248.6 ORY51673.1 - 2.3 7.8 6.7 1.8 8.1 0.2 2.7 3 0 0 3 3 3 0 zinc-ribbon domain A2L_zn_ribbon PF08792.10 ORY51673.1 - 5.1 6.9 5.6 4.4 7.1 1.8 2.5 2 1 0 2 2 2 0 A2L zinc ribbon domain Glyco_transf_17 PF04724.13 ORY51674.1 - 3.8e-05 22.9 0.0 3.8e-05 22.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 17 Glyco_transf_17 PF04724.13 ORY51675.1 - 0.00013 21.2 0.1 0.0021 17.1 0.1 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 17 CsgE PF10627.9 ORY51682.1 - 0.12 12.7 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Curli assembly protein CsgE Ribosomal_S6 PF01250.17 ORY51683.1 - 1.2e-17 63.9 0.0 3.9e-16 59.1 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S6 Vps53_N PF04100.12 ORY51684.1 - 1.8e-53 181.9 6.3 2.4e-53 181.5 6.3 1.1 1 0 0 1 1 1 1 Vps53-like, N-terminal Spc7 PF08317.11 ORY51684.1 - 0.0023 16.9 6.5 0.0038 16.2 6.5 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein CEP63 PF17045.5 ORY51684.1 - 0.0023 17.9 5.7 0.0039 17.1 5.7 1.3 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa Vps54_N PF10475.9 ORY51684.1 - 0.0042 16.4 4.8 0.0062 15.9 4.8 1.1 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Macoilin PF09726.9 ORY51684.1 - 0.046 12.3 10.5 0.064 11.8 10.5 1.1 1 0 0 1 1 1 0 Macoilin family DUF3275 PF11679.8 ORY51684.1 - 0.072 13.1 1.0 0.15 12.1 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3275) NBD94 PF16830.5 ORY51684.1 - 0.3 11.5 3.9 0.39 11.1 0.6 2.5 3 0 0 3 3 3 0 Nucleotide-Binding Domain 94 of RH Dict-STAT-coil PF09267.10 ORY51684.1 - 0.68 10.3 6.4 1.2 9.5 4.0 2.3 1 1 1 2 2 2 0 Dictyostelium STAT, coiled coil Osmo_CC PF08946.10 ORY51684.1 - 0.71 10.2 2.4 3.8 7.8 0.1 2.5 2 0 0 2 2 2 0 Osmosensory transporter coiled coil ApoO PF09769.9 ORY51684.1 - 0.78 9.7 2.6 21 5.1 0.0 2.3 2 0 0 2 2 2 0 Apolipoprotein O RecG_N PF17190.4 ORY51684.1 - 1.1 10.1 4.3 1.2 9.9 2.4 1.9 2 0 0 2 2 2 0 RecG N-terminal helical domain WD40 PF00400.32 ORY51685.1 - 1.4e-109 354.9 52.9 2e-10 41.0 0.1 12.6 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY51685.1 - 3.2e-44 149.1 10.1 7e-05 23.0 0.0 11.5 1 1 10 11 11 11 11 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY51685.1 - 8.8e-26 90.6 20.1 0.018 13.7 0.1 11.4 1 1 11 12 12 12 10 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY51685.1 - 2.4e-15 56.7 12.3 0.0019 17.6 0.0 7.1 3 3 2 6 6 6 5 WD40-like domain Ge1_WD40 PF16529.5 ORY51685.1 - 3e-15 56.0 28.1 0.0052 15.8 1.0 9.8 1 1 6 9 9 9 6 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4506 PF14958.6 ORY51685.1 - 5.6e-05 22.7 0.2 2.3 7.7 0.0 4.5 3 1 1 5 5 5 2 Domain of unknown function (DUF4506) DUF1036 PF06282.11 ORY51685.1 - 0.00065 20.2 1.5 1.4 9.4 0.0 5.2 3 1 6 9 9 9 1 Protein of unknown function (DUF1036) PD40 PF07676.12 ORY51685.1 - 0.046 13.7 5.0 27 4.9 0.0 5.8 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat DUF642 PF04862.12 ORY51685.1 - 0.062 13.1 0.0 0.85 9.4 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF642) SPATA1_C PF15743.5 ORY51686.1 - 0.013 15.5 5.0 0.024 14.7 5.0 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus DUF3015 PF11220.8 ORY51686.1 - 0.043 13.7 1.1 0.11 12.4 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) FUSC PF04632.12 ORY51686.1 - 0.14 10.7 1.0 0.21 10.1 1.0 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4407 PF14362.6 ORY51686.1 - 1.4 8.2 4.7 2.5 7.4 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4355 PF14265.6 ORY51686.1 - 2.9 8.1 9.3 5.8 7.2 9.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) TMPIT PF07851.13 ORY51686.1 - 9.7 5.3 6.1 17 4.6 6.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein D5_N PF08706.11 ORY51687.1 - 3.5e-09 37.1 0.0 2.9e-08 34.1 0.0 2.3 1 1 0 1 1 1 1 D5 N terminal like D5_N PF08706.11 ORY51688.1 - 4.2e-10 40.1 0.5 1.3e-09 38.5 0.5 1.8 1 0 0 1 1 1 1 D5 N terminal like PPL4 PF18188.1 ORY51688.1 - 0.00038 20.4 0.0 0.00091 19.2 0.0 1.6 1 0 0 1 1 1 1 Prim-pol 4 DUF3439 PF11921.8 ORY51688.1 - 2.7 8.0 5.9 6.7 6.7 5.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Stanniocalcin PF03298.13 ORY51690.1 - 0.13 11.6 0.2 0.19 11.0 0.2 1.2 1 0 0 1 1 1 0 Stanniocalcin family NACHT PF05729.12 ORY51691.1 - 2e-05 24.5 0.0 6.4e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 NACHT domain V-ATPase_G PF03179.15 ORY51691.1 - 0.035 14.6 0.6 6.7 7.3 0.0 2.4 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Peptidase_M9_N PF08453.10 ORY51691.1 - 0.051 13.3 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 Peptidase family M9 N-terminal WRW PF10206.9 ORY51691.1 - 0.14 12.6 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Ank_4 PF13637.6 ORY51692.1 - 1.2e-29 102.2 0.1 8.4e-12 45.4 0.0 2.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY51692.1 - 7.4e-26 90.6 0.1 9.1e-26 90.3 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 ORY51692.1 - 8.7e-24 82.9 0.2 1.3e-07 31.7 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 ORY51692.1 - 4.7e-17 60.3 0.0 2.9e-06 27.2 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 ORY51692.1 - 1.3e-15 57.3 0.3 3.8e-09 36.6 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) VWA_3_C PF18571.1 ORY51692.1 - 5.5e-05 22.9 3.4 1 9.3 0.0 3.2 3 0 0 3 3 3 2 von Willebrand factor type A C-terminal domain Imm_superinfect PF14373.6 ORY51692.1 - 0.021 14.7 0.0 24 5.0 0.0 3.2 3 0 0 3 3 3 0 Superinfection immunity protein DUF4988 PF16378.5 ORY51692.1 - 0.021 14.5 0.0 4.9 6.8 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function Doppel PF11466.8 ORY51692.1 - 0.15 11.8 0.3 4.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Prion-like protein Doppel UPF0051 PF01458.17 ORY51692.1 - 0.34 10.5 1.9 28 4.3 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein family (UPF0051) Ank PF00023.30 ORY51693.1 - 1.3e-27 95.0 0.5 1.3e-08 34.9 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 ORY51693.1 - 2.4e-26 92.1 0.1 8.6e-25 87.1 0.2 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY51693.1 - 8.3e-25 86.8 0.2 4.6e-12 46.2 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY51693.1 - 3.3e-23 79.2 0.1 3.2e-07 30.1 0.0 3.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 ORY51693.1 - 1e-19 70.3 0.3 2.9e-07 30.6 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) VWA_3_C PF18571.1 ORY51693.1 - 0.0037 17.1 0.4 0.36 10.7 0.1 2.7 3 0 0 3 3 3 1 von Willebrand factor type A C-terminal domain Imm_superinfect PF14373.6 ORY51693.1 - 0.0076 16.1 0.0 4.5 7.3 0.0 3.1 3 0 0 3 3 3 1 Superinfection immunity protein DUF4988 PF16378.5 ORY51693.1 - 0.078 12.6 0.0 3.7 7.2 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function SRC-1 PF08832.10 ORY51693.1 - 0.16 13.0 0.6 3.5 8.7 0.1 2.6 1 1 2 3 3 3 0 Steroid receptor coactivator DUF4233 PF14017.6 ORY51694.1 - 0.012 16.0 1.8 49 4.3 0.1 4.2 4 1 1 5 5 5 0 Protein of unknown function (DUF4233) Rtt106_N PF18215.1 ORY51694.1 - 0.19 11.5 11.8 60 3.5 0.1 5.3 4 1 1 5 5 5 0 Histone chaperone Rtt106 N-terminal domain Golgin_A5 PF09787.9 ORY51781.1 - 0.00079 19.0 26.9 0.00079 19.0 26.9 12.3 2 2 10 12 12 12 1 Golgin subfamily A member 5 Filament PF00038.21 ORY51781.1 - 0.00084 19.0 10.1 0.00084 19.0 10.1 12.0 1 1 6 9 9 9 4 Intermediate filament protein DUF4201 PF13870.6 ORY51781.1 - 0.0047 16.7 5.1 0.0047 16.7 5.1 14.6 3 3 7 14 14 14 3 Domain of unknown function (DUF4201) TolA_bind_tri PF16331.5 ORY51781.1 - 0.025 14.6 0.1 0.025 14.6 0.1 21.3 12 9 10 22 22 22 0 TolA binding protein trimerisation Img2 PF05046.14 ORY51781.1 - 0.89 9.9 7.8 53 4.2 0.1 6.1 4 0 0 4 4 4 0 Mitochondrial large subunit ribosomal protein (Img2) ABC_tran PF00005.27 ORY51782.1 - 1.7e-45 154.9 0.1 8.5e-23 81.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 ORY51782.1 - 2e-23 82.2 0.2 5.4e-23 80.8 0.2 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY51782.1 - 6e-15 55.8 2.5 0.00013 21.9 0.0 4.7 4 1 1 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY51782.1 - 5.6e-13 48.8 0.0 0.00025 20.5 0.0 3.5 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 ORY51782.1 - 8.8e-08 31.8 0.8 0.0027 17.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY51782.1 - 3.1e-06 27.2 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 ORY51782.1 - 5.5e-06 26.4 0.1 0.077 13.1 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.6 ORY51782.1 - 2.3e-05 24.3 1.5 0.25 11.0 0.9 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 ORY51782.1 - 6.6e-05 23.5 10.7 0.033 14.7 0.0 3.7 5 0 0 5 5 3 2 AAA domain AAA_22 PF13401.6 ORY51782.1 - 6.6e-05 23.2 0.2 0.15 12.3 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.6 ORY51782.1 - 9.6e-05 22.8 1.1 0.37 11.2 0.1 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_24 PF13479.6 ORY51782.1 - 0.00029 20.6 0.0 0.58 9.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 ORY51782.1 - 0.0044 17.4 0.0 2.4 8.6 0.0 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 ORY51782.1 - 0.0057 16.6 1.2 0.24 11.3 0.1 2.9 3 0 0 3 3 3 1 NACHT domain AAA_33 PF13671.6 ORY51782.1 - 0.006 16.8 0.0 4.7 7.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY51782.1 - 0.0066 16.2 0.0 1.4 8.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_27 PF13514.6 ORY51782.1 - 0.0086 15.7 0.1 2.5 7.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 ORY51782.1 - 0.0089 16.4 0.1 4.1 7.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 ORY51782.1 - 0.013 15.7 0.0 3.1 8.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 ORY51782.1 - 0.013 15.5 0.1 1.1 9.2 0.0 2.8 2 0 0 2 2 2 0 Dynamin family AAA_14 PF13173.6 ORY51782.1 - 0.02 14.9 0.1 7.6 6.6 0.0 3.0 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 ORY51782.1 - 0.034 14.3 0.1 13 6.1 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 ORY51782.1 - 0.041 13.1 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.6 ORY51782.1 - 0.049 14.2 0.0 9.8 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORY51782.1 - 0.051 13.1 0.0 6 6.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region cobW PF02492.19 ORY51782.1 - 0.071 12.7 0.1 20 4.7 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 ORY51782.1 - 0.084 11.8 0.1 3.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FeoB_N PF02421.18 ORY51782.1 - 0.094 12.2 0.1 2.1 7.8 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B IstB_IS21 PF01695.17 ORY51782.1 - 0.097 12.4 0.2 26 4.5 0.0 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein SbcCD_C PF13558.6 ORY51782.1 - 0.13 12.5 0.4 1.4 9.2 0.1 2.8 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit Ploopntkinase3 PF18751.1 ORY51782.1 - 0.21 11.5 0.8 17 5.3 0.0 2.8 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 Cytidylate_kin PF02224.18 ORY51782.1 - 0.46 10.2 5.4 6.7 6.4 0.1 2.8 3 0 0 3 3 3 0 Cytidylate kinase DUF87 PF01935.17 ORY51782.1 - 1.4 8.9 4.2 42 4.1 0.2 3.4 3 1 0 3 3 3 0 Helicase HerA, central domain DUF727 PF05303.12 ORY51783.1 - 2.7e-08 33.8 0.0 3.4e-08 33.5 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF727) FAM72 PF14976.6 ORY51784.1 - 5.4e-52 175.8 4.9 8.4e-52 175.2 4.9 1.3 1 0 0 1 1 1 1 FAM72 protein SHIPPO-rpt PF07004.12 ORY51785.1 - 1.6e-17 63.5 43.7 7.4e-06 26.6 5.4 6.5 6 0 0 6 6 6 6 Sperm-tail PG-rich repeat Met_10 PF02475.16 ORY51786.1 - 8.1e-68 228.1 0.0 1.2e-67 227.5 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 ORY51786.1 - 0.053 12.7 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase CDP-OH_P_transf PF01066.21 ORY51787.1 - 1.1e-18 67.7 5.8 4.3e-18 65.8 0.1 3.4 3 2 0 3 3 3 1 CDP-alcohol phosphatidyltransferase DUF1422 PF07226.11 ORY51787.1 - 0.067 13.2 3.2 3.6 7.6 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) CybS PF05328.12 ORY51787.1 - 4.2 7.0 6.6 2.4 7.9 0.3 2.7 3 0 0 3 3 3 0 CybS, succinate dehydrogenase cytochrome B small subunit NatB_MDM20 PF09797.9 ORY51789.1 - 4.2e-71 239.9 7.3 4.2e-71 239.9 7.3 2.4 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.6 ORY51789.1 - 8.6e-05 23.0 2.1 0.37 11.7 0.1 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TIP120 PF08623.10 ORY51789.1 - 0.0047 16.7 0.4 0.021 14.6 0.4 2.1 1 0 0 1 1 1 1 TATA-binding protein interacting (TIP20) TPR_19 PF14559.6 ORY51789.1 - 0.046 14.2 4.9 0.31 11.6 0.9 3.9 3 1 0 4 4 4 0 Tetratricopeptide repeat Telomere_reg-2 PF10193.9 ORY51789.1 - 0.18 12.2 2.3 0.33 11.4 0.2 2.7 2 0 0 2 2 2 0 Telomere length regulation protein TPR_16 PF13432.6 ORY51789.1 - 0.2 12.4 1.4 3.1 8.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat HMGL-like PF00682.19 ORY51790.1 - 4.6e-91 305.0 0.1 7.3e-91 304.4 0.1 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 ORY51790.1 - 5e-24 84.7 2.4 1e-23 83.7 2.4 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Arm PF00514.23 ORY51791.1 - 9.8e-07 28.6 1.8 3.6 7.8 0.0 5.5 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat Ribosomal_S19e PF01090.19 ORY51792.1 - 7.6e-60 200.6 0.3 8.6e-60 200.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e PC-Esterase PF13839.6 ORY51793.1 - 0.0075 16.1 0.0 0.052 13.3 0.0 2.0 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Ribosomal_L31e PF01198.19 ORY51794.1 - 1.6e-37 127.6 1.9 2.1e-37 127.2 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e AATF-Che1 PF13339.6 ORY51795.1 - 3.5e-32 112.0 1.0 3.5e-32 112.0 1.0 4.4 4 1 0 4 4 4 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 ORY51795.1 - 5.4e-32 110.2 0.5 5.4e-32 110.2 0.5 3.2 2 1 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal Nop14 PF04147.12 ORY51795.1 - 0.0012 17.2 44.9 0.0012 17.2 44.9 3.0 2 1 1 3 3 3 1 Nop14-like family SDA1 PF05285.12 ORY51795.1 - 0.0028 17.2 44.5 0.0028 17.2 44.5 2.7 2 1 0 2 2 2 1 SDA1 eIF-3c_N PF05470.12 ORY51795.1 - 0.81 7.9 29.1 0.3 9.3 17.4 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Galactosyl_T PF01762.21 ORY51796.1 - 6.4e-08 32.6 0.0 2.6e-07 30.7 0.0 2.0 1 1 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 ORY51796.1 - 0.11 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Fringe-like ESSS PF10183.9 ORY51796.1 - 0.11 12.8 0.1 5.4 7.3 0.2 2.6 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Proteasome PF00227.26 ORY51798.1 - 3e-49 167.1 0.3 4.1e-49 166.7 0.3 1.2 1 0 0 1 1 1 1 Proteasome subunit TPR_1 PF00515.28 ORY51799.1 - 3.5e-40 134.2 9.1 2.9e-06 26.8 0.7 12.4 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_2 PF07719.17 ORY51799.1 - 2.4e-35 117.8 13.6 1.2e-05 25.1 0.1 13.3 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_14 PF13428.6 ORY51799.1 - 1.9e-30 102.9 4.2 0.01 16.6 0.0 11.6 9 3 3 12 12 11 6 Tetratricopeptide repeat TPR_19 PF14559.6 ORY51799.1 - 6.2e-28 97.1 9.8 4.2e-05 24.0 0.0 8.5 5 3 3 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 ORY51799.1 - 2.1e-26 92.0 22.9 7e-06 26.3 0.8 10.6 4 4 6 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.6 ORY51799.1 - 5.7e-24 84.5 12.0 0.0022 18.6 0.5 9.1 7 1 2 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 ORY51799.1 - 9.2e-23 78.5 17.1 0.022 14.9 0.2 12.0 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_7 PF13176.6 ORY51799.1 - 1.5e-21 74.7 8.3 0.00028 20.7 0.1 9.9 9 2 1 10 10 9 3 Tetratricopeptide repeat TPR_6 PF13174.6 ORY51799.1 - 7.8e-19 67.0 9.8 0.036 14.7 0.1 10.1 10 1 0 10 10 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 ORY51799.1 - 9.7e-19 66.8 8.2 0.0022 17.6 0.0 11.7 10 2 2 12 12 12 4 TPR repeat TPR_9 PF13371.6 ORY51799.1 - 3.9e-14 52.6 2.0 0.00043 20.4 0.0 6.9 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY51799.1 - 1.3e-12 47.2 10.8 0.77 10.3 0.0 11.7 12 1 2 14 14 13 2 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY51799.1 - 2.7e-11 43.5 9.3 0.00026 21.2 0.7 6.0 5 2 2 7 7 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 ORY51799.1 - 2.1e-10 40.1 15.9 0.017 14.9 0.0 10.1 11 1 0 11 11 10 2 Tetratricopeptide repeat TPR_4 PF07721.14 ORY51799.1 - 5.4e-07 29.6 0.0 13 6.8 0.0 6.5 8 0 0 8 8 5 0 Tetratricopeptide repeat TOM20_plant PF06552.12 ORY51799.1 - 0.0017 18.1 5.9 0.073 12.8 0.0 5.3 6 1 1 7 7 7 1 Plant specific mitochondrial import receptor subunit TOM20 DUF627 PF04781.12 ORY51799.1 - 0.0064 16.5 4.6 6.5 6.8 0.0 5.2 4 2 0 4 4 4 1 Protein of unknown function (DUF627) Fis1_TPR_C PF14853.6 ORY51799.1 - 0.013 15.6 3.7 24 5.1 0.1 5.1 6 0 0 6 6 4 0 Fis1 C-terminal tetratricopeptide repeat HPPK PF01288.20 ORY51799.1 - 0.064 13.8 0.0 4 8.0 0.0 3.0 2 0 0 2 2 2 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) PPR PF01535.20 ORY51799.1 - 0.16 12.3 3.7 57 4.3 0.1 5.3 6 0 0 6 6 4 0 PPR repeat NARP1 PF12569.8 ORY51799.1 - 0.26 10.1 0.0 0.26 10.1 0.0 7.3 6 1 2 8 8 5 0 NMDA receptor-regulated protein 1 TPR_3 PF07720.12 ORY51799.1 - 0.47 10.5 11.9 6.9 6.8 0.4 5.3 6 0 0 6 6 4 0 Tetratricopeptide repeat CDC27 PF09507.10 ORY51799.1 - 2.2 7.5 35.4 4.1 6.7 35.4 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Sel1 PF08238.12 ORY51799.1 - 2.5 8.9 8.4 35 5.3 0.1 5.4 5 0 0 5 5 4 0 Sel1 repeat Sec39 PF08314.11 ORY51800.1 - 7.4e-27 94.2 0.7 7.4e-27 94.2 0.7 2.5 2 1 0 2 2 2 1 Secretory pathway protein Sec39 TFIIF_beta PF02270.15 ORY51801.1 - 3.9e-22 78.2 0.3 6.6e-22 77.4 0.3 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 ORY51801.1 - 7.8e-16 59.0 1.2 1.8e-15 57.8 1.2 1.8 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus CobA_CobO_BtuR PF02572.15 ORY51801.1 - 0.049 13.9 2.5 0.088 13.1 2.5 1.5 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP SseB_C PF14581.6 ORY51801.1 - 0.092 12.9 1.7 0.12 12.5 0.6 1.8 2 0 0 2 2 2 0 SseB protein C-terminal domain DUF3035 PF11233.8 ORY51801.1 - 0.53 10.6 4.7 0.35 11.1 1.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3035) Phage_fiber_2 PF03406.13 ORY51801.1 - 1.5 8.5 7.3 0.14 11.7 0.7 2.6 3 0 0 3 3 3 0 Phage tail fibre repeat IPK PF03770.16 ORY51802.1 - 6.5e-41 140.4 0.1 7.9e-41 140.1 0.1 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase Dynamin_N PF00350.23 ORY51803.1 - 0.0028 17.7 0.4 0.0049 16.9 0.4 1.4 1 0 0 1 1 1 1 Dynamin family TFIIA PF03153.13 ORY51803.1 - 0.0031 17.6 4.7 0.0033 17.5 4.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DCA16 PF15349.6 ORY51803.1 - 0.53 9.8 0.1 0.53 9.8 0.1 2.2 2 0 0 2 2 2 0 DDB1- and CUL4-associated factor 16 DUF4820 PF16091.5 ORY51803.1 - 4.3 6.6 7.7 6.6 6.0 7.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4820) DDE_3 PF13358.6 ORY51804.1 - 1.2e-19 70.5 0.0 3.6e-19 69.0 0.0 1.7 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_33 PF13592.6 ORY51804.1 - 0.0078 15.8 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix Cluap1 PF10234.9 ORY51805.1 - 0.027 13.9 2.1 0.058 12.8 2.1 1.6 1 0 0 1 1 1 0 Clusterin-associated protein-1 TFIID-18kDa PF02269.16 ORY51805.1 - 0.065 13.3 0.6 0.84 9.7 0.3 2.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit COQ9 PF08511.11 ORY51807.1 - 6.4e-33 112.4 0.0 9.9e-33 111.8 0.0 1.3 1 0 0 1 1 1 1 COQ9 zf-C2H2 PF00096.26 ORY51809.1 - 0.01 16.3 2.2 0.01 16.3 2.2 2.7 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-Di19 PF05605.12 ORY51809.1 - 0.68 10.3 5.7 2 8.8 0.3 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 ORY51809.1 - 0.91 10.1 8.5 14 6.3 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY51811.1 - 2.1e-09 37.4 20.3 0.054 14.4 0.7 5.3 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY51811.1 - 7.2e-09 35.6 21.7 0.013 15.9 1.1 5.3 5 1 0 5 5 5 3 Zinc finger, C2H2 type zf-Di19 PF05605.12 ORY51811.1 - 0.001 19.3 15.4 0.0077 16.5 0.6 4.0 4 1 0 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 ORY51811.1 - 0.0011 19.2 12.6 0.23 11.9 0.2 4.8 5 0 0 5 5 5 2 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 ORY51811.1 - 0.0046 16.6 4.7 0.45 10.2 0.0 3.4 2 1 1 3 3 3 1 Zinc-fingers and homeoboxes C2H2 finger domain Zn-C2H2_12 PF18112.1 ORY51811.1 - 0.0048 17.3 6.9 0.45 11.0 0.3 3.6 3 0 0 3 3 3 2 Autophagy receptor zinc finger-C2H2 domain FOXP-CC PF16159.5 ORY51811.1 - 0.006 17.2 6.2 8.7 7.1 0.0 3.8 4 1 1 5 5 4 1 FOXP coiled-coil domain zf-C2H2_3rep PF18868.1 ORY51811.1 - 0.018 15.7 5.7 0.022 15.5 3.4 2.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 ORY51811.1 - 0.023 14.7 9.9 1.1 9.3 0.3 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Mss51 PF13824.6 ORY51811.1 - 0.034 14.2 8.1 0.27 11.4 1.5 3.2 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 CpXC PF14353.6 ORY51811.1 - 0.041 13.9 4.2 0.14 12.2 0.7 2.7 2 1 0 2 2 2 0 CpXC protein zf-H2C2_2 PF13465.6 ORY51811.1 - 0.044 14.2 23.3 0.081 13.4 0.1 5.1 5 1 0 5 5 5 0 Zinc-finger double domain zf-C2HE PF16278.5 ORY51811.1 - 0.046 14.2 6.1 0.62 10.6 0.0 3.5 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger OrsD PF12013.8 ORY51811.1 - 0.087 13.3 9.0 3.8 8.0 0.2 4.0 4 1 1 5 5 5 0 Orsellinic acid/F9775 biosynthesis cluster protein D Actin_micro PF17003.5 ORY51811.1 - 0.1 11.7 7.6 0.71 9.0 0.9 2.6 1 1 2 3 3 3 0 Putative actin-like family zf-BED PF02892.15 ORY51811.1 - 0.17 11.9 10.1 15 5.7 0.4 4.3 3 1 1 4 4 4 0 BED zinc finger DUF629 PF04780.12 ORY51811.1 - 0.24 9.9 0.1 0.24 9.9 0.1 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF629) zinc_ribbon_15 PF17032.5 ORY51811.1 - 0.32 11.8 5.4 1.3 9.8 0.9 2.6 1 1 1 2 2 2 0 zinc-ribbon family zf-C2H2_jaz PF12171.8 ORY51811.1 - 0.54 10.6 0.1 0.54 10.6 0.1 4.6 5 1 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 ORY51811.1 - 1.5 9.2 14.7 2.8 8.3 0.3 4.5 3 1 2 5 5 5 0 C2H2 type zinc-finger (2 copies) PPP4R2 PF09184.11 ORY51812.1 - 0.026 14.1 6.0 0.03 13.9 6.0 1.1 1 0 0 1 1 1 0 PPP4R2 CNDH2_C PF16858.5 ORY51812.1 - 0.043 13.7 6.3 0.053 13.4 6.3 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term BUD22 PF09073.10 ORY51812.1 - 1.3 8.3 14.4 1.7 7.9 14.4 1.1 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.12 ORY51812.1 - 1.4 7.0 14.2 1.8 6.6 14.2 1.1 1 0 0 1 1 1 0 Nop14-like family PPL5 PF18168.1 ORY51812.1 - 1.5 8.0 5.6 2.1 7.5 5.6 1.1 1 0 0 1 1 1 0 Prim-pol family 5 TFIIA PF03153.13 ORY51812.1 - 5.4 6.9 14.8 7.1 6.5 14.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SDA1 PF05285.12 ORY51812.1 - 8 5.8 21.0 10 5.4 21.0 1.1 1 0 0 1 1 1 0 SDA1 Gly_transf_sug PF04488.15 ORY51813.1 - 9.3e-07 29.4 0.1 2.9e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 ORY51813.1 - 0.014 14.8 0.1 0.02 14.3 0.1 1.4 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Galactosyl_T PF01762.21 ORY51814.1 - 6.5e-12 45.7 0.1 1.5e-06 28.2 0.1 2.9 1 1 1 2 2 2 2 Galactosyltransferase Galactosyl_T PF01762.21 ORY51815.1 - 1.7e-11 44.3 0.1 3.8e-06 26.8 0.1 3.0 1 1 1 2 2 2 2 Galactosyltransferase Fringe PF02434.16 ORY51815.1 - 0.014 14.9 0.0 0.039 13.4 0.0 1.7 2 0 0 2 2 2 0 Fringe-like DUF4148 PF13663.6 ORY51816.1 - 0.094 12.9 0.1 0.094 12.9 0.1 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4148) SURF6 PF04935.12 ORY51817.1 - 2.9e-27 95.8 51.4 7.4e-25 87.9 51.4 2.4 1 1 0 1 1 1 1 Surfeit locus protein 6 RRP14 PF15459.6 ORY51817.1 - 4.5e-09 36.8 1.0 4.5e-09 36.8 1.0 4.5 4 3 0 4 4 4 1 60S ribosome biogenesis protein Rrp14 BAR PF03114.18 ORY51818.1 - 5.9e-38 130.9 11.6 7e-38 130.6 11.6 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 ORY51818.1 - 2.8e-15 55.6 0.1 5.3e-15 54.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY51818.1 - 8.2e-14 51.2 0.0 1.4e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY51818.1 - 5.8e-10 38.7 0.0 1.1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain TPR_MLP1_2 PF07926.12 ORY51818.1 - 7.5e-05 22.8 4.1 7.5e-05 22.8 4.1 2.2 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.19 ORY51818.1 - 0.0087 14.0 4.9 0.015 13.3 4.9 1.3 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Macscav_rec PF03523.13 ORY51818.1 - 0.038 13.9 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Macrophage scavenger receptor DBI_PRT PF02277.17 ORY51818.1 - 0.15 11.3 0.3 0.28 10.4 0.0 1.6 2 0 0 2 2 2 0 Phosphoribosyltransferase Mis14 PF08641.12 ORY51818.1 - 0.23 11.8 6.6 1.6 9.0 2.2 2.3 2 0 0 2 2 2 0 Kinetochore protein Mis14 like ATP-synt_E PF05680.12 ORY51818.1 - 0.8 10.1 6.7 1.3 9.5 0.3 2.3 2 0 0 2 2 2 0 ATP synthase E chain Seryl_tRNA_N PF02403.22 ORY51818.1 - 2.2 8.6 7.3 4.5 7.5 0.2 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain UPF0242 PF06785.11 ORY51818.1 - 2.6 8.1 8.3 2.1 8.4 1.5 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus SHE3 PF17078.5 ORY51818.1 - 5.3 6.7 12.3 5.5 6.6 5.9 2.1 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Cyclin_N PF00134.23 ORY51819.1 - 0.00024 20.9 0.0 0.0007 19.3 0.0 1.8 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 ORY51819.1 - 0.0007 20.0 1.1 0.0015 19.0 0.1 2.2 2 1 0 2 2 2 1 Cyclin Dicty_REP PF05086.12 ORY51819.1 - 0.095 10.7 0.6 0.17 9.8 0.6 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CBM-like PF14683.6 ORY51820.1 - 0.065 13.1 0.1 0.081 12.8 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain III Kinesin PF00225.23 ORY51821.1 - 1.3e-52 178.8 0.0 1.3e-52 178.8 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ORY51821.1 - 2.4e-09 37.3 0.0 1.2e-08 35.0 0.0 2.3 1 1 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 ORY51821.1 - 0.0068 16.7 1.8 0.077 13.3 0.0 3.1 2 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 ORY51821.1 - 0.029 14.5 0.3 0.24 11.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 ORY51821.1 - 0.093 13.1 0.0 0.093 13.1 0.0 2.5 2 1 1 3 3 3 0 AAA ATPase domain RGS PF00615.19 ORY51822.1 - 4.1e-19 69.0 5.4 1.3e-18 67.4 0.3 3.6 4 0 0 4 4 4 1 Regulator of G protein signaling domain TPR_19 PF14559.6 ORY51822.1 - 0.14 12.7 1.1 5.7 7.5 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Pro_isomerase PF00160.21 ORY51823.1 - 4.2e-50 170.1 0.0 8.1e-50 169.2 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 ORY51823.1 - 3.9e-08 33.8 1.0 0.022 15.6 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Raptor_N PF14538.6 ORY51824.1 - 4.9e-69 230.9 0.0 9e-69 230.1 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 ORY51824.1 - 9.3e-12 45.3 3.1 0.07 14.0 0.1 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat Cnd1 PF12717.7 ORY51824.1 - 1.8e-10 41.1 1.2 1.8e-06 28.1 0.2 2.6 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 ORY51824.1 - 3.5e-09 36.2 4.2 0.0019 18.3 0.3 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 ORY51824.1 - 3.1e-06 27.5 0.1 0.0048 17.3 0.0 3.3 1 1 1 2 2 2 2 HEAT repeats ANAPC4_WD40 PF12894.7 ORY51824.1 - 3.8e-05 23.9 0.0 8.4 6.8 0.0 4.6 1 1 4 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain HEAT_EZ PF13513.6 ORY51824.1 - 0.00039 20.9 1.1 0.054 14.0 0.1 3.0 2 0 0 2 2 2 1 HEAT-like repeat Adaptin_N PF01602.20 ORY51824.1 - 0.0037 15.9 1.9 0.011 14.3 1.9 1.7 1 1 0 1 1 1 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 ORY51824.1 - 0.016 15.3 0.0 0.036 14.2 0.0 1.5 1 0 0 1 1 1 0 V-ATPase subunit H Mcl1_mid PF12341.8 ORY51824.1 - 0.13 11.6 0.0 0.39 10.0 0.0 1.7 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region Atx10homo_assoc PF09759.9 ORY51824.1 - 0.17 11.9 0.1 0.47 10.5 0.1 1.8 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain S4 PF01479.25 ORY51825.1 - 3.6e-12 45.8 1.0 3.6e-12 45.8 1.0 1.9 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.19 ORY51825.1 - 0.00022 22.0 0.3 0.00059 20.7 0.1 1.9 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain AAA_6 PF12774.7 ORY51826.1 - 4.9e-156 518.7 0.0 1.5e-155 517.1 0.0 1.9 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 ORY51826.1 - 1.7e-146 488.4 12.9 1.7e-146 488.4 12.9 2.2 2 0 0 2 2 1 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 ORY51826.1 - 4e-111 371.1 0.0 8.7e-111 370.0 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 ORY51826.1 - 3.1e-108 361.0 0.1 1.6e-107 358.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 ORY51826.1 - 7.3e-89 296.6 0.3 7.3e-89 296.6 0.3 3.5 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_7 PF12775.7 ORY51826.1 - 1.1e-84 282.4 0.1 2.2e-82 275.0 0.0 3.4 4 0 0 4 4 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 ORY51826.1 - 2.3e-65 219.4 0.0 8.4e-65 217.6 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 ORY51826.1 - 3.1e-55 187.6 6.3 9.7e-55 186.0 6.3 1.9 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 ORY51826.1 - 1.8e-46 157.1 0.0 2.5e-43 147.0 0.0 3.3 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 ORY51826.1 - 1.6e-33 115.5 0.1 7.7e-33 113.3 0.1 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 ORY51826.1 - 7.8e-18 64.8 0.0 4e-06 26.9 0.0 6.0 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 ORY51826.1 - 5e-17 62.0 0.1 1.8e-16 60.1 0.1 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 ORY51826.1 - 1.2e-06 29.0 0.0 0.99 9.8 0.0 4.7 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 ORY51826.1 - 7.3e-05 23.2 0.0 3.4 8.0 0.0 4.7 4 0 0 4 4 4 1 AAA ATPase domain RNA_helicase PF00910.22 ORY51826.1 - 0.00013 22.3 0.1 4 7.9 0.0 4.0 3 0 0 3 3 3 1 RNA helicase AAA_22 PF13401.6 ORY51826.1 - 0.00058 20.2 0.0 5.6 7.3 0.0 4.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 ORY51826.1 - 0.00078 20.0 0.1 0.92 10.1 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 ORY51826.1 - 0.0051 16.6 0.1 2.3 7.9 0.2 3.5 3 0 0 3 3 3 1 AAA domain EF-hand_1 PF00036.32 ORY51826.1 - 0.0061 16.0 1.0 0.027 14.0 1.0 2.2 1 0 0 1 1 1 1 EF hand AAA_33 PF13671.6 ORY51826.1 - 0.0095 16.1 0.1 19 5.4 0.0 3.7 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 ORY51826.1 - 0.016 14.3 0.4 0.069 12.2 0.0 2.2 3 0 0 3 3 3 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 ORY51826.1 - 0.067 12.6 0.7 16 4.8 0.0 3.1 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI EF-hand_7 PF13499.6 ORY51826.1 - 0.073 13.5 0.2 0.51 10.8 0.2 2.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 ORY51826.1 - 0.081 12.9 1.2 0.4 10.7 1.2 2.3 1 0 0 1 1 1 0 EF-hand domain ABC_tran PF00005.27 ORY51826.1 - 0.11 13.0 0.0 19 5.8 0.0 3.3 2 0 0 2 2 2 0 ABC transporter HATPase_c PF02518.26 ORY51827.1 - 1.7e-08 35.0 0.2 1.2e-07 32.2 0.2 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 ORY51827.1 - 3e-06 27.1 0.0 1.3e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 ORY51827.1 - 1e-05 25.2 0.1 0.0003 20.5 0.0 2.9 2 1 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 ORY51827.1 - 4.5e-05 23.3 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TRAF6_Z2 PF18048.1 ORY51827.1 - 1 9.5 4.5 6.6 6.9 0.0 3.0 3 0 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 CTNNBL PF08216.11 ORY51828.1 - 2.4e-30 104.8 0.1 2.4e-30 104.8 0.1 2.3 3 0 0 3 3 3 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.23 ORY51828.1 - 0.00036 20.5 0.5 0.38 10.9 0.1 3.5 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat DUF5578 PF17741.1 ORY51828.1 - 0.061 12.7 1.5 1 8.7 0.1 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5578) ParcG PF10274.9 ORY51828.1 - 0.074 13.2 1.1 0.51 10.4 0.2 2.5 1 1 2 3 3 3 0 Parkin co-regulated protein MOR2-PAG1_C PF14225.6 ORY51828.1 - 0.11 12.4 2.5 7.1 6.4 0.1 2.7 3 0 0 3 3 3 0 Cell morphogenesis C-terminal DUF2812 PF11193.8 ORY51828.1 - 0.11 12.7 0.1 0.25 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2812) WD40 PF00400.32 ORY51829.1 - 7.2e-21 74.1 2.6 3.8e-06 27.5 0.1 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY51829.1 - 0.00025 21.3 0.0 0.96 9.8 0.1 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain bZIP_1 PF00170.21 ORY51829.1 - 0.022 14.8 1.5 0.04 14.0 1.5 1.3 1 0 0 1 1 1 0 bZIP transcription factor WD40_alt PF14077.6 ORY51829.1 - 0.031 14.1 0.2 0.068 13.0 0.2 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif DivIC PF04977.15 ORY51829.1 - 0.13 12.1 1.5 0.23 11.2 1.5 1.4 1 0 0 1 1 1 0 Septum formation initiator YabA PF06156.13 ORY51829.1 - 0.17 12.5 2.3 0.26 11.9 2.3 1.3 1 0 0 1 1 1 0 Initiation control protein YabA UPF0121 PF03661.13 ORY51830.1 - 2.3e-38 131.9 16.6 2.8e-38 131.7 16.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) AAA_6 PF12774.7 ORY51831.1 - 4.9e-158 525.3 0.1 8.2e-157 521.3 0.0 3.1 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 ORY51831.1 - 2.1e-141 471.7 3.3 2.1e-141 471.7 3.3 3.5 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 ORY51831.1 - 1.4e-113 379.2 0.0 1.8e-112 375.5 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 ORY51831.1 - 3.2e-108 361.0 0.1 1.4e-107 358.9 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 ORY51831.1 - 6.8e-94 313.1 1.7 6.8e-94 313.1 1.7 2.5 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 ORY51831.1 - 6e-84 280.0 0.0 7.7e-82 273.2 0.0 3.6 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 ORY51831.1 - 6e-55 185.5 0.0 2e-54 183.9 0.0 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 ORY51831.1 - 7.6e-51 173.1 10.9 7.6e-51 173.1 10.9 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 ORY51831.1 - 2.3e-47 159.9 0.0 4e-44 149.5 0.0 3.1 2 0 0 2 2 2 2 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 ORY51831.1 - 7.3e-30 103.7 0.0 4.7e-29 101.1 0.0 2.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 ORY51831.1 - 6.3e-19 68.3 0.0 1.7e-05 24.9 0.0 5.7 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 ORY51831.1 - 1.9e-18 66.5 0.1 8.4e-18 64.4 0.1 2.2 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 ORY51831.1 - 2.8e-06 27.8 0.0 0.11 13.0 0.0 4.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 ORY51831.1 - 2.6e-05 24.5 0.1 6.7 7.0 0.0 5.4 5 0 0 5 5 4 1 AAA domain AAA_16 PF13191.6 ORY51831.1 - 0.00093 19.6 0.0 4.3 7.7 0.0 4.6 4 0 0 4 4 4 1 AAA ATPase domain T2SSE PF00437.20 ORY51831.1 - 0.0051 15.9 0.0 0.49 9.4 0.0 2.8 3 0 0 3 3 3 1 Type II/IV secretion system protein EF-hand_1 PF00036.32 ORY51831.1 - 0.0083 15.6 0.1 0.046 13.3 0.1 2.5 1 0 0 1 1 1 1 EF hand AAA_33 PF13671.6 ORY51831.1 - 0.011 16.0 0.0 12 6.1 0.0 3.5 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 ORY51831.1 - 0.013 15.9 0.6 31 5.0 0.0 4.6 5 0 0 5 5 5 0 RNA helicase EF-hand_6 PF13405.6 ORY51831.1 - 0.036 14.0 0.1 0.19 11.7 0.1 2.3 1 0 0 1 1 1 0 EF-hand domain YjcZ PF13990.6 ORY51831.1 - 0.039 13.3 0.2 0.093 12.1 0.2 1.6 1 0 0 1 1 1 0 YjcZ-like protein AAA_18 PF13238.6 ORY51831.1 - 0.048 14.2 1.1 0.61 10.6 0.0 3.7 4 0 0 4 4 2 0 AAA domain AAA_30 PF13604.6 ORY51831.1 - 0.091 12.5 0.4 5.8 6.6 0.2 2.9 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 ORY51831.1 - 0.12 12.1 0.0 0.92 9.2 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain ATPase PF06745.13 ORY51831.1 - 0.18 11.1 2.4 0.92 8.8 0.0 2.7 2 0 0 2 2 2 0 KaiC MutS_V PF00488.21 ORY51832.1 - 3e-83 278.5 0.2 4.9e-83 277.8 0.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 ORY51832.1 - 2.7e-36 125.6 1.3 2.7e-36 125.6 1.3 2.1 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 ORY51832.1 - 4e-17 62.8 0.9 6.6e-16 58.8 0.0 2.6 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 ORY51832.1 - 4.4e-15 55.8 1.2 1.5e-14 54.1 1.2 2.0 1 0 0 1 1 1 1 MutS family domain IV MutS_I PF01624.20 ORY51832.1 - 4.5e-12 46.2 0.0 1e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 MutS domain I AAA_27 PF13514.6 ORY51832.1 - 0.015 14.9 0.0 0.035 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ERCC3_RAD25_C PF16203.5 ORY51833.1 - 8.9e-104 346.1 0.0 1.4e-103 345.4 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 ORY51833.1 - 1.1e-37 129.0 0.0 8.5e-37 126.1 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY51833.1 - 7.1e-17 61.9 0.0 1.7e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORY51833.1 - 3.5e-09 37.0 0.0 8.2e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 ORY51833.1 - 2e-07 30.1 0.0 3.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 ORY51833.1 - 2.4e-05 24.2 0.0 4.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase GSHPx PF00255.19 ORY51834.1 - 1e-28 99.0 0.0 1.5e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 ORY51834.1 - 0.032 14.1 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family OST3_OST6 PF04756.13 ORY51835.1 - 6.1e-91 304.8 1.8 7.2e-91 304.6 1.8 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 ORY51835.1 - 0.097 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin PLAC8 PF04749.17 ORY51836.1 - 8.7e-23 81.2 19.3 1.5e-22 80.5 19.3 1.5 1 0 0 1 1 1 1 PLAC8 family MIF4G_like_2 PF09090.11 ORY51836.1 - 0.1 12.0 4.7 0.13 11.7 4.7 1.1 1 0 0 1 1 1 0 MIF4G like Presenilin PF01080.17 ORY51836.1 - 0.86 8.3 10.5 1.1 7.9 10.5 1.1 1 0 0 1 1 1 0 Presenilin DDRGK PF09756.9 ORY51836.1 - 1.2 8.7 27.2 1.8 8.1 27.2 1.1 1 0 0 1 1 1 0 DDRGK domain Hid1 PF12722.7 ORY51836.1 - 1.2 7.1 8.4 1.5 6.8 8.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Amidohydro_1 PF01979.20 ORY51837.1 - 1.1e-65 222.3 1.7 1.7e-65 221.6 1.7 1.2 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.20 ORY51837.1 - 2.3e-56 189.3 2.2 6.3e-56 187.9 2.2 1.8 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 ORY51837.1 - 2.5e-40 136.4 0.0 6.1e-40 135.2 0.0 1.7 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.18 ORY51837.1 - 3.9e-39 133.0 0.0 9.4e-39 131.7 0.0 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 ORY51837.1 - 6.1e-07 29.3 0.2 4.4e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family LRR_8 PF13855.6 ORY51838.1 - 2.1e-08 33.8 0.2 1.2e-07 31.4 0.4 2.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY51838.1 - 0.006 17.0 0.1 0.057 13.9 0.0 2.4 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) HAD_2 PF13419.6 ORY51839.1 - 9.1e-13 48.7 0.0 1.2e-12 48.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY51839.1 - 1.5e-10 41.7 0.0 1.8e-10 41.5 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 ORY51839.1 - 0.00037 20.5 0.0 0.00088 19.3 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like ATP_sub_h PF10775.9 ORY51839.1 - 0.024 14.6 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 ATP synthase complex subunit h zf-C3HC4_2 PF13923.6 ORY51840.1 - 1.1e-06 28.3 9.7 2.4e-06 27.3 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY51840.1 - 9.4e-06 25.5 10.6 1.7e-05 24.7 10.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 ORY51840.1 - 1.2e-05 25.0 6.6 2.3e-05 24.2 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY51840.1 - 2.2e-05 24.4 11.5 2.2e-05 24.4 11.5 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-CCCH PF00642.24 ORY51840.1 - 3.3e-05 23.7 1.1 3.3e-05 23.7 1.1 1.6 2 0 0 2 2 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 ORY51840.1 - 0.00021 21.2 2.9 0.00021 21.2 2.9 1.8 2 0 0 2 2 1 1 Zinc finger domain zf-C3HC4 PF00097.25 ORY51840.1 - 0.0004 20.2 10.7 0.00087 19.1 10.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY51840.1 - 0.0017 18.4 11.1 0.0056 16.8 11.1 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 ORY51840.1 - 0.005 16.6 3.6 0.009 15.8 3.6 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF3795 PF12675.7 ORY51840.1 - 0.01 16.2 5.9 0.035 14.5 5.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3795) zf-RING_2 PF13639.6 ORY51840.1 - 0.012 16.0 9.7 0.012 16.0 9.7 1.8 2 0 0 2 2 2 0 Ring finger domain zf-CCCH_4 PF18044.1 ORY51840.1 - 0.04 13.7 2.0 0.04 13.7 2.0 2.3 2 0 0 2 2 2 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 ORY51840.1 - 0.054 14.0 1.6 0.054 14.0 1.6 1.8 2 0 0 2 2 1 0 RNA-binding, Nab2-type zinc finger Prok-RING_4 PF14447.6 ORY51840.1 - 0.06 13.2 10.1 0.24 11.3 10.1 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 ORY51840.1 - 0.23 11.6 8.4 0.063 13.4 5.3 1.7 2 0 0 2 2 2 0 zinc RING finger of MSL2 Mito_carr PF00153.27 ORY51841.1 - 6.8e-56 186.2 4.6 1.4e-20 73.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FA_hydroxylase PF04116.13 ORY51842.1 - 1.1e-23 84.1 14.8 1.1e-23 84.1 14.8 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF5090 PF17009.5 ORY51842.1 - 0.14 12.1 0.2 0.33 10.9 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) SH3_9 PF14604.6 ORY51843.1 - 9e-46 153.5 4.9 2.6e-15 56.0 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 ORY51843.1 - 1.9e-42 142.6 5.8 1.1e-14 53.7 0.1 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 ORY51843.1 - 4e-38 128.9 0.5 1e-11 44.3 0.1 3.9 4 0 0 4 4 4 3 Variant SH3 domain Cofilin_ADF PF00241.20 ORY51843.1 - 2.7e-20 72.4 0.0 6.2e-20 71.2 0.0 1.6 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF3987 PF13148.6 ORY51843.1 - 3.2 6.7 9.2 5.5 5.9 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) zf-CCHC PF00098.23 ORY51844.1 - 0.02 15.0 1.0 0.087 12.9 1.0 2.2 1 0 0 1 1 1 0 Zinc knuckle zf-CCCH_2 PF14608.6 ORY51844.1 - 0.24 11.9 2.0 1 9.9 2.0 2.2 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger GWT1 PF06423.12 ORY51846.1 - 2.5e-30 105.6 1.0 1.9e-29 102.7 1.0 2.5 1 1 0 1 1 1 1 GWT1 RF-1 PF00472.20 ORY51846.1 - 0.039 13.9 1.4 0.069 13.1 1.4 1.3 1 0 0 1 1 1 0 RF-1 domain DUF468 PF04318.12 ORY51846.1 - 0.11 13.2 0.1 0.28 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF468) AAA_5 PF07728.14 ORY51848.1 - 6.7e-122 401.9 0.2 1.9e-23 83.0 0.0 9.9 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 ORY51848.1 - 4.2e-44 149.1 5.4 1e-13 51.4 0.1 6.4 6 0 0 6 6 4 3 Midasin AAA lid domain AAA_3 PF07726.11 ORY51848.1 - 2.5e-29 101.8 0.0 6e-10 39.1 0.0 8.0 8 0 0 8 8 7 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 ORY51848.1 - 1e-25 90.7 0.4 0.0038 17.7 0.0 7.2 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 ORY51848.1 - 6.9e-25 87.6 10.8 2e-05 24.2 1.0 7.0 6 1 0 6 6 6 5 P-loop containing dynein motor region Dynein_heavy PF03028.15 ORY51848.1 - 2e-24 86.0 0.0 0.00016 21.8 0.0 6.5 6 0 0 6 6 5 4 Dynein heavy chain region D6 P-loop domain AAA_lid_5 PF17865.1 ORY51848.1 - 1.6e-20 73.2 0.0 1.3e-19 70.3 0.0 2.8 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_16 PF13191.6 ORY51848.1 - 2.3e-20 73.7 16.3 0.00098 19.5 0.1 8.0 7 1 0 7 7 6 6 AAA ATPase domain AAA_6 PF12774.7 ORY51848.1 - 1.6e-16 60.2 3.7 0.0019 17.3 0.3 8.7 8 1 0 8 8 8 3 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 ORY51848.1 - 2e-16 60.7 11.4 0.013 16.0 0.0 8.0 7 0 0 7 7 6 4 AAA domain AAA_22 PF13401.6 ORY51848.1 - 1.1e-14 54.9 4.9 0.046 14.0 0.1 7.3 6 0 0 6 6 6 3 AAA domain Sigma54_activat PF00158.26 ORY51848.1 - 1.6e-14 54.0 0.0 0.048 13.4 0.0 6.1 6 0 0 6 6 5 4 Sigma-54 interaction domain TsaE PF02367.17 ORY51848.1 - 6.4e-13 48.8 8.4 0.024 14.6 0.2 7.3 7 0 0 7 7 7 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 ORY51848.1 - 2.4e-12 47.6 5.4 0.073 13.6 0.0 7.2 6 0 0 6 6 6 2 ABC transporter AAA_30 PF13604.6 ORY51848.1 - 3.5e-12 46.4 0.2 0.069 12.9 0.1 8.2 8 2 0 8 8 7 1 AAA domain Sigma54_activ_2 PF14532.6 ORY51848.1 - 1.7e-11 44.4 5.0 0.0086 16.2 0.0 6.2 7 0 0 7 7 5 2 Sigma-54 interaction domain AAA_14 PF13173.6 ORY51848.1 - 8.4e-11 42.0 0.0 0.065 13.3 0.0 6.8 6 0 0 6 6 5 2 AAA domain T2SSE PF00437.20 ORY51848.1 - 4.4e-10 39.1 8.0 0.042 12.9 1.8 5.7 5 0 0 5 5 5 3 Type II/IV secretion system protein RsgA_GTPase PF03193.16 ORY51848.1 - 8.1e-10 38.9 7.8 0.89 9.4 0.3 6.6 6 0 0 6 6 6 2 RsgA GTPase AAA_33 PF13671.6 ORY51848.1 - 3.7e-09 36.9 0.9 5.5 7.1 0.0 7.2 6 1 0 6 6 6 0 AAA domain RNA_helicase PF00910.22 ORY51848.1 - 4.2e-09 36.8 8.5 2.4 8.6 0.1 7.7 8 1 0 8 8 6 2 RNA helicase AAA_19 PF13245.6 ORY51848.1 - 3.5e-08 33.9 0.8 0.7 10.2 0.0 6.1 5 0 0 5 5 4 2 AAA domain IstB_IS21 PF01695.17 ORY51848.1 - 1.2e-07 31.6 1.8 0.74 9.5 0.1 6.0 6 0 0 6 6 5 2 IstB-like ATP binding protein AAA_29 PF13555.6 ORY51848.1 - 1.2e-07 31.3 9.4 0.071 12.9 0.1 6.4 6 0 0 6 6 6 1 P-loop containing region of AAA domain Rad17 PF03215.15 ORY51848.1 - 4.6e-07 29.9 7.2 0.36 10.7 0.1 6.1 6 0 0 6 6 6 1 Rad17 P-loop domain NACHT PF05729.12 ORY51848.1 - 8.7e-07 29.0 12.1 0.47 10.4 0.1 6.6 7 0 0 7 7 5 2 NACHT domain Mg_chelatase PF01078.21 ORY51848.1 - 2.3e-06 27.2 6.5 2.4 7.5 0.0 7.8 10 0 0 10 10 8 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 ORY51848.1 - 5.7e-06 25.7 9.7 0.95 8.6 0.1 6.2 7 0 0 7 7 7 2 Protein of unknown function (DUF815) RuvB_N PF05496.12 ORY51848.1 - 6.9e-06 25.9 7.2 0.024 14.4 0.0 6.1 8 0 0 8 8 5 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 ORY51848.1 - 7.5e-06 25.6 9.1 0.95 9.0 0.1 5.8 6 0 0 6 6 5 1 AAA domain Viral_helicase1 PF01443.18 ORY51848.1 - 2.2e-05 24.3 2.6 4.8 6.8 0.1 4.8 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 ORY51848.1 - 2.3e-05 24.4 11.1 0.23 11.3 0.5 5.5 6 0 0 6 6 4 2 NTPase AAA_28 PF13521.6 ORY51848.1 - 2.8e-05 24.4 22.5 3.2 8.0 0.0 7.1 7 0 0 7 7 6 1 AAA domain SRPRB PF09439.10 ORY51848.1 - 4.8e-05 22.9 3.0 0.097 12.1 0.1 4.9 4 0 0 4 4 4 1 Signal recognition particle receptor beta subunit TniB PF05621.11 ORY51848.1 - 0.00021 20.7 0.1 2.2 7.6 0.0 5.0 5 0 0 5 5 5 1 Bacterial TniB protein AAA_8 PF12780.7 ORY51848.1 - 0.00044 19.7 4.5 2.3 7.5 0.0 5.4 6 0 0 6 6 6 1 P-loop containing dynein motor region D4 MMR_HSR1 PF01926.23 ORY51848.1 - 0.00088 19.3 5.6 8 6.6 0.0 6.0 6 0 0 6 6 5 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 ORY51848.1 - 0.0015 17.9 7.9 9.4 5.5 0.0 6.0 6 0 0 6 6 6 0 Zeta toxin Roc PF08477.13 ORY51848.1 - 0.0018 18.5 8.7 23 5.2 0.1 6.4 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase CPT PF07931.12 ORY51848.1 - 0.002 18.0 4.2 0.84 9.4 0.0 5.6 6 1 0 6 6 4 1 Chloramphenicol phosphotransferase-like protein PduV-EutP PF10662.9 ORY51848.1 - 0.0026 17.5 9.5 0.12 12.1 0.2 4.7 5 0 0 5 5 4 1 Ethanolamine utilisation - propanediol utilisation VWA PF00092.28 ORY51848.1 - 0.0045 17.3 0.7 0.016 15.5 0.7 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain ATPase PF06745.13 ORY51848.1 - 0.0098 15.3 2.8 1.9 7.8 0.1 3.9 4 0 0 4 4 3 1 KaiC DEAD PF00270.29 ORY51848.1 - 0.035 13.9 2.0 14 5.4 0.1 3.8 3 0 0 3 3 3 0 DEAD/DEAH box helicase PRK PF00485.18 ORY51848.1 - 0.057 13.1 3.4 22 4.7 0.1 4.4 4 0 0 4 4 4 0 Phosphoribulokinase / Uridine kinase family MeaB PF03308.16 ORY51848.1 - 0.069 12.1 1.6 20 4.0 0.1 3.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF321 PF03778.13 ORY51848.1 - 0.13 12.0 0.0 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF321) dNK PF01712.19 ORY51848.1 - 0.17 11.7 8.9 40 4.0 0.0 5.8 6 0 0 6 6 6 0 Deoxynucleoside kinase SRP54 PF00448.22 ORY51848.1 - 0.26 10.9 11.0 2.3 7.8 0.3 4.5 5 0 0 5 5 4 0 SRP54-type protein, GTPase domain Rad51 PF08423.11 ORY51848.1 - 0.57 9.4 3.2 3 7.0 0.1 2.7 3 0 0 3 3 2 0 Rad51 DUF927 PF06048.11 ORY51848.1 - 0.81 9.2 4.9 6.8 6.2 0.6 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF927) ATP_bind_1 PF03029.17 ORY51848.1 - 1.1 9.0 15.0 13 5.5 0.2 5.5 6 0 0 6 6 5 0 Conserved hypothetical ATP binding protein Glyco_trans_2_3 PF13632.6 ORY51850.1 - 1e-11 45.1 0.0 1e-11 45.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 STT3 PF02516.14 ORY51851.1 - 5.4e-146 487.3 33.6 2.2e-142 475.5 30.7 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit FKBP_C PF00254.28 ORY51852.1 - 7.5e-33 112.7 0.1 1.1e-31 109.0 0.0 2.5 2 1 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 ORY51852.1 - 1.2e-21 77.2 0.1 1.2e-21 77.2 0.1 2.7 2 1 0 2 2 2 1 Nucleoplasmin-like domain Presenilin PF01080.17 ORY51852.1 - 0.36 9.6 5.4 0.43 9.3 5.4 1.2 1 0 0 1 1 1 0 Presenilin CENP-N PF05238.13 ORY51852.1 - 2.2 7.5 7.2 3.8 6.7 7.2 1.4 1 0 0 1 1 1 0 Kinetochore protein CHL4 like GAGA_bind PF06217.12 ORY51852.1 - 5.9 7.1 14.9 8.6 6.5 14.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family SLC12 PF03522.15 ORY51852.1 - 6.3 5.7 7.8 8.9 5.2 7.8 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Biopterin_H PF00351.21 ORY51853.1 - 3.3e-156 519.4 0.0 4.1e-156 519.1 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT_4 PF13291.6 ORY51853.1 - 0.0012 19.4 0.0 0.0026 18.3 0.0 1.5 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 ORY51853.1 - 0.0078 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 ACT domain Rotamase PF00639.21 ORY51856.1 - 2.3e-21 76.6 0.0 3e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 ORY51856.1 - 5.8e-16 59.1 0.0 7.8e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 ORY51856.1 - 8.8e-07 28.9 6.4 2.6e-06 27.4 6.0 2.0 1 1 1 2 2 2 1 WW domain Rotamase_2 PF13145.6 ORY51856.1 - 0.11 13.3 0.0 0.15 12.9 0.0 1.2 1 0 0 1 1 1 0 PPIC-type PPIASE domain MitMem_reg PF13012.6 ORY51857.1 - 6.9e-32 110.2 0.4 1.1e-31 109.6 0.4 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 ORY51857.1 - 4.5e-16 58.9 0.0 7.1e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease FANCI_S4 PF14678.6 ORY51858.1 - 3.5e-32 111.5 0.2 1e-31 110.0 0.2 1.8 1 0 0 1 1 1 1 FANCI solenoid 4 FANCI_HD2 PF14680.6 ORY51858.1 - 9.6e-27 93.8 0.5 9.6e-27 93.8 0.5 3.0 2 1 0 3 3 3 1 FANCI helical domain 2 FANCI_S2 PF14676.6 ORY51858.1 - 1.2e-21 77.7 0.0 7e-21 75.2 0.0 2.5 1 0 0 1 1 1 1 FANCI solenoid 2 FANCI_S1 PF14675.6 ORY51858.1 - 3e-14 53.1 0.7 2.2e-13 50.3 0.0 2.7 3 0 0 3 3 3 1 FANCI solenoid 1 FANCI_HD1 PF14679.6 ORY51858.1 - 2.1e-12 46.8 0.0 2.3e-11 43.5 0.0 2.9 2 0 0 2 2 2 1 FANCI helical domain 1 FANCI_S3 PF14677.6 ORY51858.1 - 1.1e-09 38.4 0.0 7e-09 35.7 0.0 2.4 1 0 0 1 1 1 1 FANCI solenoid 3 MCM6_C PF18263.1 ORY51858.1 - 0.0032 17.7 0.2 0.014 15.6 0.2 2.1 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain Kin17_mid PF10357.9 ORY51859.1 - 2.6e-47 159.8 0.7 4.2e-47 159.2 0.7 1.3 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 ORY51859.1 - 0.0065 16.8 7.4 0.012 16.0 7.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY51859.1 - 0.018 15.3 7.1 0.032 14.5 7.1 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Ribosomal_L18p PF00861.22 ORY51859.1 - 0.027 14.9 0.1 0.14 12.6 0.1 2.1 2 0 0 2 2 2 0 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Herpes_UL32 PF06070.11 ORY51859.1 - 0.11 10.3 5.6 0.14 9.9 5.6 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 IQ PF00612.27 ORY51860.1 - 7.8e-10 37.7 23.8 0.012 15.3 0.6 5.7 5 0 0 5 5 5 3 IQ calmodulin-binding motif TT_ORF2 PF02957.15 ORY51860.1 - 0.17 12.8 0.4 0.68 10.9 0.4 2.1 1 0 0 1 1 1 0 TT viral ORF2 MRP-S32 PF10210.9 ORY51860.1 - 0.92 10.1 6.2 1.8 9.2 0.4 3.3 3 0 0 3 3 3 0 Mitochondrial 28S ribosomal protein S32 CsgE PF10627.9 ORY51861.1 - 0.12 12.7 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Curli assembly protein CsgE UCH_1 PF13423.6 ORY51863.1 - 2e-81 274.1 0.0 3.3e-81 273.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 ORY51863.1 - 3.8e-19 69.8 0.0 6.2e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 ORY51863.1 - 2.7e-09 36.9 0.0 1.2e-08 34.8 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase IRF-2BP1_2 PF11261.8 ORY51863.1 - 0.47 10.1 1.4 0.75 9.4 0.1 2.0 2 0 0 2 2 2 0 Interferon regulatory factor 2-binding protein zinc finger Peptidase_M41 PF01434.18 ORY51864.1 - 1.4e-62 211.0 1.0 2.3e-62 210.2 1.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 ORY51864.1 - 4.8e-46 156.5 0.0 1.1e-45 155.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY51864.1 - 1.1e-12 47.5 0.0 6.1e-12 45.1 0.0 2.2 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 ORY51864.1 - 5.4e-07 30.1 1.7 7.3e-05 23.2 0.5 4.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 ORY51864.1 - 9.2e-06 25.5 0.1 7.5e-05 22.5 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 ORY51864.1 - 9.6e-06 25.0 0.0 3.2e-05 23.3 0.0 1.7 1 1 0 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 ORY51864.1 - 1.2e-05 25.3 0.0 8.5e-05 22.6 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 ORY51864.1 - 0.00022 21.0 0.0 0.00057 19.7 0.0 1.8 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 ORY51864.1 - 0.00042 20.6 0.1 0.026 14.8 0.1 2.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 ORY51864.1 - 0.00059 19.1 0.2 0.0028 16.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 ORY51864.1 - 0.0016 18.5 0.0 0.045 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 ORY51864.1 - 0.0025 17.9 0.0 0.0073 16.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 ORY51864.1 - 0.0039 16.9 0.1 0.01 15.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY51864.1 - 0.0046 17.5 0.0 0.01 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 ORY51864.1 - 0.014 14.9 0.1 0.22 11.1 0.1 2.4 1 1 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 ORY51864.1 - 0.015 14.4 0.0 0.028 13.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 ORY51864.1 - 0.016 15.6 0.1 0.049 14.0 0.0 1.9 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 ORY51864.1 - 0.017 15.1 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 ORY51864.1 - 0.023 14.1 0.1 0.058 12.8 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 ORY51864.1 - 0.025 14.8 0.0 0.054 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 ORY51864.1 - 0.03 14.2 0.0 0.084 12.7 0.0 1.7 1 1 0 1 1 1 0 Bacterial dnaA protein NACHT PF05729.12 ORY51864.1 - 0.038 13.9 0.2 0.38 10.6 0.0 2.5 3 0 0 3 3 3 0 NACHT domain AAA_33 PF13671.6 ORY51864.1 - 0.038 14.1 0.1 0.075 13.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY51864.1 - 0.05 14.0 0.1 0.15 12.5 0.0 2.0 2 1 0 2 2 1 0 RNA helicase AAA_7 PF12775.7 ORY51864.1 - 0.062 12.8 0.0 0.52 9.8 0.0 2.2 1 1 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 ORY51864.1 - 0.073 12.3 0.0 0.25 10.6 0.0 2.0 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.16 ORY51864.1 - 0.08 12.4 0.2 0.18 11.2 0.2 1.5 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 ORY51864.1 - 0.083 12.2 0.1 4.3 6.6 0.0 2.8 3 0 0 3 3 3 0 KaiC ATPase_2 PF01637.18 ORY51864.1 - 0.12 12.3 0.2 8.6 6.2 0.0 2.5 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea Pkinase PF00069.25 ORY51865.1 - 1.6e-69 234.2 0.0 2.2e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY51865.1 - 1.9e-31 109.3 0.0 2.8e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY51865.1 - 1.6e-06 27.6 0.1 8.7e-06 25.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 ORY51865.1 - 2.1e-05 25.1 0.0 0.00079 20.1 0.0 3.0 1 1 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 ORY51865.1 - 0.00091 18.3 0.1 0.0014 17.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 ORY51865.1 - 0.0026 17.4 0.0 0.99 9.0 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 ORY51865.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family TFIIF_alpha PF05793.12 ORY51865.1 - 1.1 7.8 2.4 1.8 7.0 2.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SOG2 PF10428.9 ORY51865.1 - 5.3 6.1 8.3 6.9 5.7 0.4 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein tRNA_anti-codon PF01336.25 ORY51866.1 - 1.1e-09 38.1 3.8 2.3e-09 37.1 3.8 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 ORY51866.1 - 0.0018 18.1 0.3 0.0034 17.2 0.3 1.4 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 STN1_2 PF09170.10 ORY51866.1 - 0.0078 16.4 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 Stn1 PF10451.9 ORY51866.1 - 0.013 14.4 0.3 0.02 13.9 0.3 1.2 1 0 0 1 1 1 0 Telomere regulation protein Stn1 DUF1506 PF07405.11 ORY51868.1 - 0.086 13.0 1.1 14 5.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1506) AAA PF00004.29 ORY51869.1 - 4.8e-43 146.7 0.0 1e-42 145.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY51869.1 - 3.2e-10 39.6 0.1 8.8e-10 38.2 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 ORY51869.1 - 1.2e-07 32.1 0.0 3.7e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 ORY51869.1 - 1.2e-07 31.5 0.5 3.1e-07 30.3 0.5 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 ORY51869.1 - 2.2e-06 27.7 0.0 1.2e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY51869.1 - 4.1e-06 27.3 0.0 6.1e-05 23.5 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY51869.1 - 3.9e-05 23.9 0.1 0.0083 16.4 0.0 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 ORY51869.1 - 7.3e-05 22.6 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 ORY51869.1 - 0.00087 18.6 0.0 0.0026 17.0 0.0 1.8 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 ORY51869.1 - 0.0015 18.7 0.0 0.0032 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY51869.1 - 0.0015 19.0 0.1 0.021 15.4 0.0 2.6 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 ORY51869.1 - 0.0019 17.9 0.0 0.0043 16.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF2072 PF09845.9 ORY51869.1 - 0.0044 17.3 0.7 0.01 16.1 0.7 1.5 1 0 0 1 1 1 1 Zn-ribbon containing protein AAA_3 PF07726.11 ORY51869.1 - 0.0044 16.9 0.0 0.017 15.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 ORY51869.1 - 0.007 15.6 0.0 0.024 13.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 ORY51869.1 - 0.0072 15.7 0.3 0.019 14.3 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 ORY51869.1 - 0.01 16.1 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 ORY51869.1 - 0.011 15.2 0.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein SlyX PF04102.12 ORY51869.1 - 0.014 16.0 1.8 0.036 14.7 1.0 2.1 2 0 0 2 2 1 0 SlyX ATPase PF06745.13 ORY51869.1 - 0.015 14.7 0.0 0.044 13.1 0.0 1.8 1 0 0 1 1 1 0 KaiC TsaE PF02367.17 ORY51869.1 - 0.02 14.9 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 ORY51869.1 - 0.021 14.5 0.0 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 ORY51869.1 - 0.026 14.3 0.0 0.094 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORY51869.1 - 0.033 13.7 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 ORY51869.1 - 0.035 14.1 0.0 0.082 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY51869.1 - 0.039 14.3 0.0 0.085 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 ORY51869.1 - 0.054 12.6 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 ORY51869.1 - 0.059 13.7 0.1 0.63 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ORY51869.1 - 0.069 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORY51869.1 - 0.075 12.3 0.0 0.18 11.1 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_13 PF13166.6 ORY51869.1 - 0.087 11.5 0.5 3.7 6.1 0.5 2.1 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 ORY51869.1 - 0.095 13.2 0.1 0.75 10.3 0.0 2.6 2 1 0 2 2 2 0 ABC transporter Tropomyosin PF00261.20 ORY51869.1 - 0.12 11.7 4.5 0.12 11.7 1.4 2.1 2 0 0 2 2 2 0 Tropomyosin ATG16 PF08614.11 ORY51869.1 - 0.14 12.3 2.8 0.25 11.5 2.8 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 ORY51869.1 - 0.33 10.7 3.1 0.89 9.4 3.1 1.7 1 0 0 1 1 1 0 Septum formation initiator Uso1_p115_head PF04869.14 ORY51870.1 - 1.5e-75 254.2 0.4 3e-75 253.2 0.1 1.6 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Arm_vescicular PF18770.1 ORY51870.1 - 7.1e-10 38.7 0.9 6.4e-09 35.6 1.2 2.6 2 0 0 2 2 2 1 Armadillo tether-repeat of vescicular transport factor HEAT_2 PF13646.6 ORY51870.1 - 0.0036 17.7 2.3 2.1 8.8 0.3 4.2 3 2 0 3 3 3 1 HEAT repeats Arm_2 PF04826.13 ORY51870.1 - 0.007 15.9 4.8 1 8.8 0.3 3.1 2 1 1 3 3 3 2 Armadillo-like RTP1_C1 PF10363.9 ORY51870.1 - 0.029 14.5 0.5 0.57 10.4 0.0 3.1 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 ORY51870.1 - 0.062 13.4 4.1 3.2 7.9 0.0 4.8 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 ORY51870.1 - 1.2 9.6 9.2 64 4.2 0.1 5.4 5 0 0 5 5 5 0 HEAT repeat Atx10homo_assoc PF09759.9 ORY51870.1 - 1.3 9.0 9.9 25 5.0 0.4 4.8 4 2 1 6 6 6 0 Spinocerebellar ataxia type 10 protein domain Sld5 PF05916.11 ORY51871.1 - 3.3e-18 66.1 0.0 4.9e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Pkinase PF00069.25 ORY51872.1 - 1.8e-40 139.0 0.0 2.6e-37 128.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY51872.1 - 8.6e-13 48.2 0.0 2.3e-11 43.5 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY51872.1 - 0.00038 19.4 0.0 0.00071 18.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY51872.1 - 0.12 12.3 0.0 0.37 10.7 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family ChAPs PF09295.10 ORY51873.1 - 1.9e-130 435.4 0.0 4.2e-128 427.7 0.0 2.1 1 1 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 ORY51873.1 - 0.00065 20.3 2.8 76 4.5 0.0 6.3 3 1 3 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY51873.1 - 0.0054 16.8 0.1 11 6.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY51873.1 - 0.0059 17.1 0.2 2 9.0 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY51873.1 - 0.079 13.1 1.1 20 5.6 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DnaJ PF00226.31 ORY51874.1 - 1.9e-23 82.4 0.1 5.3e-23 80.9 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain DUF1977 PF09320.11 ORY51874.1 - 5.4e-21 74.8 4.4 5.4e-21 74.8 4.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) TPR_2 PF07719.17 ORY51874.1 - 0.08 13.1 0.0 0.59 10.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY51874.1 - 0.12 13.2 0.1 0.36 11.8 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat CDC45 PF02724.14 ORY51876.1 - 0.29 9.4 15.9 0.54 8.5 15.9 1.4 1 0 0 1 1 1 0 CDC45-like protein GPP34 PF05719.11 ORY51878.1 - 0.087 12.9 0.0 0.25 11.4 0.0 1.7 2 0 0 2 2 2 0 Golgi phosphoprotein 3 (GPP34) Kelch_4 PF13418.6 ORY51879.1 - 6.5e-08 32.5 8.2 6.6e-05 22.8 0.1 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 ORY51879.1 - 6.1e-07 29.3 5.7 0.41 10.7 0.0 5.9 5 1 1 6 6 6 3 Kelch motif Kelch_3 PF13415.6 ORY51879.1 - 2.3e-05 24.5 19.5 9.2e-05 22.6 0.1 6.4 7 0 0 7 7 7 2 Galactose oxidase, central domain Kelch_6 PF13964.6 ORY51879.1 - 0.0036 17.5 4.1 0.49 10.8 0.1 4.0 2 1 1 3 3 3 1 Kelch motif Myosin_head PF00063.21 ORY51880.1 - 1.4e-258 859.7 3.9 2.1e-258 859.1 3.9 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 ORY51880.1 - 1.1e-23 83.5 2.0 3.4e-23 81.9 2.0 2.0 1 0 0 1 1 1 1 DIL domain IQ PF00612.27 ORY51880.1 - 4.4e-20 69.5 34.3 1.3e-06 27.6 0.5 6.9 7 0 0 7 7 6 5 IQ calmodulin-binding motif CALCOCO1 PF07888.11 ORY51880.1 - 0.0071 15.3 12.3 0.012 14.5 12.3 1.2 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like AAA_22 PF13401.6 ORY51880.1 - 0.02 15.2 0.3 0.1 12.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Retrotran_gag_3 PF14244.6 ORY51880.1 - 0.037 13.9 0.3 0.49 10.2 0.1 2.5 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF16 PF01519.16 ORY51880.1 - 0.11 13.0 3.4 0.45 11.0 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 AAA_16 PF13191.6 ORY51880.1 - 0.13 12.6 0.0 0.47 10.8 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain DUF724 PF05266.14 ORY51880.1 - 0.57 10.0 9.8 1.6 8.5 9.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DHR10 PF18595.1 ORY51880.1 - 0.72 9.9 11.1 0.52 10.4 0.1 3.1 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain CENP-H PF05837.12 ORY51880.1 - 0.97 9.9 7.7 3.8 8.0 7.7 2.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF641 PF04859.12 ORY51880.1 - 1.5 9.2 9.4 1.1 9.6 6.1 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.10 ORY51880.1 - 1.7 8.8 9.1 0.98 9.6 4.7 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 ORY51880.1 - 1.9 8.9 8.4 6.9 7.1 0.6 3.8 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 ORY51880.1 - 2.2 8.3 14.3 4.1 7.5 4.7 3.6 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 ORY51880.1 - 2.4 8.2 9.4 0.43 10.6 1.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) FapA PF03961.13 ORY51880.1 - 2.6 6.6 7.1 4.9 5.6 7.1 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A UPF0242 PF06785.11 ORY51880.1 - 2.9 7.9 14.2 0.3 11.1 8.9 2.1 2 0 0 2 2 1 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 ORY51880.1 - 4.4 8.0 11.0 4.4 8.0 6.3 3.1 2 1 1 3 3 3 0 Initiation control protein YabA Fez1 PF06818.15 ORY51880.1 - 7.8 6.9 16.9 9 6.7 0.5 3.0 1 1 2 3 3 3 0 Fez1 Rsc14 PF08586.10 ORY51881.1 - 0.017 15.9 3.6 0.017 15.9 3.6 6.0 5 1 1 6 6 6 0 RSC complex, Rsc14/Ldb7 subunit G-gamma PF00631.22 ORY51881.1 - 0.087 12.8 0.1 0.087 12.8 0.1 4.2 5 0 0 5 5 5 0 GGL domain Noc2 PF03715.13 ORY51882.1 - 2.5e-108 361.9 0.0 5.1e-108 360.8 0.0 1.5 2 0 0 2 2 2 1 Noc2p family Dymeclin PF09742.9 ORY51882.1 - 0.051 12.0 0.0 0.091 11.2 0.0 1.4 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein Nop14 PF04147.12 ORY51882.1 - 0.1 10.8 0.0 0.1 10.8 0.0 4.1 2 2 2 4 4 4 0 Nop14-like family Cpn60_TCP1 PF00118.24 ORY51883.1 - 1.9e-160 534.7 4.1 2.2e-160 534.5 4.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CPT PF07931.12 ORY51883.1 - 0.041 13.7 1.2 1.7 8.5 0.1 2.9 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein DEAD PF00270.29 ORY51884.1 - 3.4e-47 160.5 0.1 1.3e-46 158.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY51884.1 - 5.4e-25 87.9 0.0 2.6e-24 85.7 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 ORY51884.1 - 5.3e-15 55.4 4.8 5.3e-15 55.4 4.8 3.5 3 0 0 3 3 3 1 DBP10CT (NUC160) domain ERCC3_RAD25_C PF16203.5 ORY51884.1 - 4.6e-05 22.7 0.0 0.00012 21.4 0.0 1.6 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase bZIP_1 PF00170.21 ORY51885.1 - 0.15 12.2 10.1 0.36 11.0 10.1 1.7 1 1 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.15 ORY51885.1 - 0.67 10.1 12.2 0.91 9.7 10.8 2.0 1 1 1 2 2 2 0 Basic region leucine zipper eIF3_subunit PF08597.10 ORY51885.1 - 1.7 8.5 10.5 3.1 7.6 10.5 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Cg6151-P PF10233.9 ORY51886.1 - 3.4e-17 62.8 11.8 4e-17 62.5 11.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P COPI_assoc PF08507.10 ORY51886.1 - 2.6e-06 27.5 4.8 2.9e-06 27.3 4.8 1.1 1 0 0 1 1 1 1 COPI associated protein DUF3810 PF12725.7 ORY51886.1 - 2.2 7.5 5.5 2.7 7.3 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF3421 PF11901.8 ORY51887.1 - 1.6e-21 76.4 0.1 2.1e-07 30.9 0.0 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3421) SPG48 PF14764.6 ORY51888.1 - 0.12 12.8 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking BROMI PF14961.6 ORY51889.1 - 1.1e-185 619.5 8.3 1.9e-147 492.8 4.2 3.2 2 2 0 2 2 2 2 Broad-minded protein RabGAP-TBC PF00566.18 ORY51889.1 - 0.036 13.7 0.2 0.11 12.1 0.2 1.8 1 0 0 1 1 1 0 Rab-GTPase-TBC domain Ank_2 PF12796.7 ORY51890.1 - 6.3e-44 148.5 1.2 5e-11 43.0 0.2 7.5 5 2 2 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY51890.1 - 4.5e-41 138.7 12.2 4.2e-11 43.1 0.2 8.6 6 2 3 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 ORY51890.1 - 3e-33 112.8 18.4 1.5e-05 25.2 0.2 11.0 12 0 0 12 12 12 6 Ankyrin repeat Ank_3 PF13606.6 ORY51890.1 - 2.4e-28 95.0 17.0 0.00026 21.2 0.1 10.1 11 0 0 11 11 11 7 Ankyrin repeat Ank_5 PF13857.6 ORY51890.1 - 1.7e-26 91.9 18.4 2.6e-05 24.4 0.2 10.0 10 2 2 12 12 12 8 Ankyrin repeats (many copies) DcpS_C PF11969.8 ORY51890.1 - 0.12 12.9 0.8 2.3 8.7 0.9 2.7 3 0 0 3 3 3 0 Scavenger mRNA decapping enzyme C-term binding CPSF73-100_C PF11718.8 ORY51891.1 - 2.1e-37 128.8 0.0 3.4e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 ORY51891.1 - 5.6e-31 107.1 0.0 1.2e-30 106.0 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_6 PF16661.5 ORY51891.1 - 7.8e-23 80.9 0.0 2.8e-22 79.1 0.0 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 ORY51891.1 - 1.5e-20 74.0 0.2 2.4e-20 73.4 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 ORY51891.1 - 1.1e-14 54.1 0.0 2.3e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 ORY51891.1 - 3.2e-08 33.3 0.6 1.3e-07 31.3 0.5 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 ORY51891.1 - 3.6e-06 27.0 0.1 1.3e-05 25.2 0.1 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 ORY51891.1 - 0.001 18.3 0.0 0.0043 16.3 0.0 1.8 2 0 0 2 2 2 1 Putative beta-lactamase-like family Vps26 PF03643.15 ORY51892.1 - 3.3e-119 397.0 0.9 4e-119 396.7 0.9 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 ORY51892.1 - 0.00035 20.6 0.3 0.036 14.1 0.0 2.9 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain UQ_con PF00179.26 ORY51893.1 - 6.7e-40 136.0 0.0 8.1e-40 135.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MHC_I_2 PF14586.6 ORY51893.1 - 0.1 12.4 0.0 0.29 11.0 0.0 1.7 2 0 0 2 2 2 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 Ribosomal_L13 PF00572.18 ORY51894.1 - 4.7e-44 149.6 0.0 5.9e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Sec23_trunk PF04811.15 ORY51896.1 - 3e-67 226.7 0.0 4.8e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 ORY51896.1 - 5e-26 90.5 0.2 9e-26 89.7 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 ORY51896.1 - 1.6e-17 64.1 0.0 4.5e-17 62.6 0.0 1.8 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 ORY51896.1 - 2.1e-16 59.7 4.6 4.4e-16 58.7 4.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 ORY51896.1 - 1.6e-11 44.0 0.0 6.1e-11 42.1 0.0 2.0 1 0 0 1 1 1 1 Gelsolin repeat Harakiri PF15196.6 ORY51896.1 - 0.11 13.0 0.1 92 3.6 0.0 3.3 3 0 0 3 3 3 0 Activator of apoptosis harakiri Spt20 PF12090.8 ORY51896.1 - 0.48 10.0 6.7 0.74 9.4 6.7 1.2 1 0 0 1 1 1 0 Spt20 family UTP15_C PF09384.10 ORY51897.1 - 3.6e-43 146.8 0.0 6e-43 146.0 0.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 ORY51897.1 - 2.9e-26 91.2 7.8 1.2e-05 25.9 0.1 6.9 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY51897.1 - 2.1e-11 43.9 0.0 0.0025 18.1 0.0 4.1 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 ORY51897.1 - 0.03 13.7 0.2 1.6 8.0 0.0 2.8 2 2 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 ORY51897.1 - 0.098 11.3 0.9 7.1 5.1 0.0 3.2 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Ribosomal_L23 PF00276.20 ORY51898.1 - 3.8e-10 40.0 0.0 4.9e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L23 ODC_AZ PF02100.17 ORY51899.1 - 8.2e-14 51.6 0.0 2.1e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme DUF1751 PF08551.10 ORY51900.1 - 1.2e-19 70.7 3.9 1.2e-19 70.7 3.9 1.9 2 0 0 2 2 2 1 Eukaryotic integral membrane protein (DUF1751) DUF2723 PF11028.8 ORY51900.1 - 0.024 14.5 3.2 0.33 10.9 3.2 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2723) Rhomboid PF01694.22 ORY51900.1 - 0.14 12.1 11.8 0.29 11.1 11.8 1.5 1 0 0 1 1 1 0 Rhomboid family TPR_1 PF00515.28 ORY51901.1 - 4.4e-47 156.1 28.1 3.5e-08 32.9 0.0 10.9 10 1 0 10 10 10 10 Tetratricopeptide repeat TPR_2 PF07719.17 ORY51901.1 - 1.6e-41 137.1 21.7 8.3e-05 22.4 0.0 10.5 10 0 0 10 10 10 10 Tetratricopeptide repeat TPR_8 PF13181.6 ORY51901.1 - 5.5e-38 126.0 13.5 0.0011 19.0 0.0 10.5 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.6 ORY51901.1 - 6.1e-26 88.9 14.7 0.005 17.1 0.1 10.6 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_11 PF13414.6 ORY51901.1 - 5.7e-24 83.5 23.3 1.4e-08 34.2 0.2 8.8 5 2 4 9 9 9 5 TPR repeat TPR_14 PF13428.6 ORY51901.1 - 2.3e-22 77.7 7.9 0.027 15.3 0.3 8.7 2 2 7 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.6 ORY51901.1 - 1.7e-21 76.6 7.0 0.0011 19.6 0.1 6.2 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 ORY51901.1 - 3.3e-20 72.4 15.2 2.1e-07 31.4 1.3 6.8 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 ORY51901.1 - 2e-17 61.9 14.0 0.19 11.8 0.1 9.6 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 ORY51901.1 - 5.9e-17 61.7 18.9 0.0026 18.0 1.5 8.2 4 2 4 8 8 8 6 Tetratricopeptide repeat TPR_6 PF13174.6 ORY51901.1 - 1.5e-13 50.4 18.7 1.3 9.8 0.0 10.3 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.6 ORY51901.1 - 1.1e-09 38.3 4.4 0.32 11.2 0.0 5.8 5 1 0 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY51901.1 - 1.2e-08 35.1 12.1 6e-07 29.6 3.2 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.9 ORY51901.1 - 0.038 13.7 0.4 4 7.1 0.0 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) Fis1_TPR_C PF14853.6 ORY51901.1 - 0.097 12.8 1.1 8.5 6.5 0.2 3.8 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat SNAP PF14938.6 ORY51901.1 - 0.31 10.4 6.5 16 4.8 0.1 3.9 3 1 1 4 4 4 0 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 ORY51901.1 - 6.4 6.8 7.5 30 4.7 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.32 ORY51902.1 - 3.7e-10 40.2 10.5 0.00039 21.2 0.3 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY51902.1 - 1.6e-05 25.1 0.1 0.077 13.3 0.0 4.0 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain AAA_6 PF12774.7 ORY51903.1 - 3.7e-161 535.6 0.0 8.7e-160 531.1 0.0 3.0 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 ORY51903.1 - 1.5e-133 445.8 10.9 1.5e-133 445.8 10.9 3.7 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 ORY51903.1 - 5.7e-117 390.3 0.0 1.3e-116 389.1 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 ORY51903.1 - 5.5e-105 350.4 2.0 7.4e-104 346.7 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 ORY51903.1 - 2e-92 308.3 3.2 2e-92 308.3 3.2 2.9 2 0 0 2 2 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 ORY51903.1 - 2e-81 271.8 0.0 7.5e-79 263.4 0.0 3.4 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 ORY51903.1 - 1.1e-63 213.9 0.1 4.6e-63 211.9 0.0 2.3 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 ORY51903.1 - 2.6e-52 178.0 6.3 2.6e-52 178.0 6.3 2.2 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 ORY51903.1 - 4.6e-46 155.8 0.0 9.9e-44 148.3 0.0 3.2 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 ORY51903.1 - 9.6e-31 106.5 0.1 5.7e-30 104.1 0.0 2.6 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 ORY51903.1 - 2.6e-19 69.3 0.1 1.3e-18 67.1 0.1 2.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 ORY51903.1 - 6.3e-18 65.1 0.0 8.5e-05 22.6 0.0 5.7 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 ORY51903.1 - 3.8e-05 24.0 2.1 10 6.4 0.0 6.0 6 0 0 6 6 5 0 AAA domain ResIII PF04851.15 ORY51903.1 - 0.00083 19.4 8.8 0.06 13.3 1.8 4.0 4 0 0 4 4 3 2 Type III restriction enzyme, res subunit AAA_16 PF13191.6 ORY51903.1 - 0.001 19.5 0.1 3.5 8.0 0.0 4.1 3 0 0 3 3 2 1 AAA ATPase domain AAA PF00004.29 ORY51903.1 - 0.0048 17.3 11.0 1.5 9.2 0.1 5.6 7 0 0 7 7 5 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 ORY51903.1 - 0.0083 16.5 0.1 4.4 7.8 0.0 3.7 3 0 0 3 3 3 1 RNA helicase AAA_24 PF13479.6 ORY51903.1 - 0.016 15.0 0.2 11 5.7 0.1 3.7 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 ORY51903.1 - 0.062 13.8 0.8 0.68 10.5 0.0 3.3 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 ORY51903.1 - 0.54 10.0 5.0 3 7.5 0.2 3.2 3 0 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 ORY51903.1 - 2 8.3 6.0 4.4 7.1 0.0 4.2 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea WD40 PF00400.32 ORY51904.1 - 1.4e-06 28.9 0.2 0.022 15.6 0.1 3.4 3 1 0 3 3 3 2 WD domain, G-beta repeat SGL PF08450.12 ORY51904.1 - 0.0029 17.2 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region ANAPC4_WD40 PF12894.7 ORY51904.1 - 0.0061 16.8 0.0 0.016 15.5 0.0 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain HlyD_D4 PF16572.5 ORY51904.1 - 0.092 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB His_Phos_2 PF00328.22 ORY51905.1 - 1.9e-85 287.5 0.1 2.4e-85 287.2 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 ORY51905.1 - 3.6e-38 129.6 0.2 1.2e-37 128.0 0.2 2.0 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 ORY51905.1 - 5.3e-07 29.4 0.0 1.8e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 RimK-like ATP-grasp domain His_Phos_1 PF00300.22 ORY51905.1 - 0.034 13.8 0.1 3 7.5 0.0 2.4 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) ATP-grasp_3 PF02655.14 ORY51905.1 - 0.041 13.9 0.1 0.16 12.0 0.1 2.0 1 1 0 1 1 1 0 ATP-grasp domain WD40 PF00400.32 ORY51906.1 - 5e-36 122.1 28.1 1.3e-06 29.0 0.8 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 ORY51906.1 - 1.3e-10 41.0 0.3 2.9e-10 39.9 0.3 1.6 1 0 0 1 1 1 1 F-box-like WD40_like PF17005.5 ORY51906.1 - 1.5e-07 31.0 3.3 1e-05 25.0 0.3 2.1 2 0 0 2 2 2 2 WD40-like domain F-box PF00646.33 ORY51906.1 - 3e-07 30.2 0.1 7.2e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 ORY51906.1 - 5.8e-07 29.7 3.5 2.9 8.2 0.0 5.6 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY51906.1 - 4.7e-05 22.2 14.8 0.056 12.1 0.1 5.8 2 1 4 6 6 6 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORY51906.1 - 0.0067 15.4 2.0 7 5.5 0.0 4.0 2 2 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein SR-25 PF10500.9 ORY51906.1 - 0.14 11.8 5.0 0.21 11.2 5.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.13 ORY51908.1 - 0.021 14.9 42.6 0.4 10.6 28.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PSP1 PF04468.12 ORY51909.1 - 7.7e-35 119.1 2.3 7.7e-35 119.1 2.3 1.8 3 0 0 3 3 3 1 PSP1 C-terminal conserved region TRAPP PF04051.16 ORY51911.1 - 4e-41 140.1 0.0 5.1e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Peptidase_C11 PF03415.14 ORY51912.1 - 0.18 11.1 0.0 0.19 11.1 0.0 1.0 1 0 0 1 1 1 0 Clostripain family MULE PF10551.9 ORY51913.1 - 2e-07 31.4 0.2 0.024 15.0 0.0 2.7 1 1 1 2 2 2 2 MULE transposase domain Transposase_mut PF00872.18 ORY51913.1 - 0.056 12.3 0.1 0.1 11.5 0.1 1.3 1 0 0 1 1 1 0 Transposase, Mutator family Wbp11 PF09429.10 ORY51914.1 - 0.048 14.1 1.0 0.048 14.1 1.0 1.8 2 0 0 2 2 2 0 WW domain binding protein 11 CsoS2_M PF12288.8 ORY51915.1 - 0.076 12.4 1.0 0.09 12.2 1.0 1.0 1 0 0 1 1 1 0 Carboxysome shell peptide mid-region zf-Dof PF02701.15 ORY51915.1 - 0.61 10.3 4.2 0.47 10.6 2.1 1.9 1 1 1 2 2 2 0 Dof domain, zinc finger SHR-BD PF06650.12 ORY51917.1 - 9.2e-78 261.3 0.7 7.5e-75 251.8 0.0 4.1 3 1 1 4 4 4 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 ORY51917.1 - 7e-74 248.6 1.9 8e-70 235.3 0.0 4.3 5 0 0 5 5 5 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 ORY51917.1 - 4e-69 232.0 7.5 1.2e-65 220.7 1.0 2.8 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13_mid_rpt PF16910.5 ORY51917.1 - 1.3e-65 221.2 1.4 1.9e-64 217.4 0.1 3.7 4 0 0 4 4 4 1 Repeating coiled region of VPS13 Chorein_N PF12624.7 ORY51917.1 - 4.4e-36 123.5 0.1 1.6e-35 121.8 0.1 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 ORY51917.1 - 1.6e-08 34.7 0.6 1.6e-07 31.6 0.0 2.7 3 0 0 3 3 3 1 Autophagy-related protein C terminal domain Apt1 PF10351.9 ORY51917.1 - 0.018 13.9 0.9 0.52 9.1 0.1 2.7 3 0 0 3 3 3 0 Golgi-body localisation protein domain Mannosyl_trans2 PF04188.13 ORY51918.1 - 3e-66 224.6 31.2 3.8e-66 224.2 31.2 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) CsgE PF10627.9 ORY51921.1 - 0.12 12.7 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Curli assembly protein CsgE S_4TM PF18159.1 ORY51922.1 - 0.041 13.2 0.9 0.044 13.1 0.9 1.0 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain ParA PF10609.9 ORY51923.1 - 1.7e-96 322.5 0.0 1.9e-96 322.3 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase ArsA_ATPase PF02374.15 ORY51923.1 - 1.5e-08 34.2 0.3 2.2e-05 23.8 0.1 2.8 1 1 0 2 2 2 2 Anion-transporting ATPase CbiA PF01656.23 ORY51923.1 - 2.1e-08 34.3 0.0 7.9e-08 32.4 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 ORY51923.1 - 2.2e-06 27.7 0.1 2.7e-05 24.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 ORY51923.1 - 0.0026 17.1 0.0 0.0057 16.0 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.6 ORY51923.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.18 ORY51923.1 - 0.02 14.4 0.1 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RsgA_GTPase PF03193.16 ORY51923.1 - 0.024 14.5 0.1 0.047 13.6 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase NB-ARC PF00931.22 ORY51923.1 - 0.034 13.3 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MeaB PF03308.16 ORY51923.1 - 0.12 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PcrB PF01884.17 ORY51923.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 PcrB family CLP1_P PF16575.5 ORY51923.1 - 0.21 11.3 0.0 0.44 10.3 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_15 PF13175.6 ORY51923.1 - 0.28 10.8 0.1 0.37 10.5 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain RRM_1 PF00076.22 ORY51924.1 - 2.9e-14 52.6 0.2 5.4e-14 51.8 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 ORY51924.1 - 3e-07 31.1 0.0 5.4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 ORY51924.1 - 1.4e-06 28.1 1.9 3.9e-06 26.7 1.9 1.8 1 0 0 1 1 1 1 Zinc finger domain RRM_occluded PF16842.5 ORY51924.1 - 0.00034 20.4 0.0 0.0019 18.0 0.0 2.1 2 0 0 2 2 2 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 ORY51924.1 - 0.00036 20.5 0.1 0.00072 19.5 0.1 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 ORY51924.1 - 0.00065 19.7 0.1 0.0023 17.9 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif zf-CCCH_3 PF15663.5 ORY51924.1 - 0.0007 19.8 0.1 0.0021 18.3 0.1 1.8 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH PF00642.24 ORY51924.1 - 0.00078 19.3 2.3 0.00078 19.3 2.3 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 ORY51924.1 - 0.0039 17.6 1.3 0.011 16.2 1.3 1.8 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 ORY51924.1 - 0.007 16.2 2.7 0.014 15.1 2.7 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger DUF4863 PF16155.5 ORY51924.1 - 0.018 14.9 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4863) RRM_7 PF16367.5 ORY51924.1 - 0.067 13.3 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif zinc-ribbons_6 PF07191.12 ORY51924.1 - 2 8.4 10.8 5.6 7.0 10.9 1.7 1 1 0 1 1 1 0 zinc-ribbons DPM2 PF07297.12 ORY51925.1 - 3.8e-30 104.0 0.5 4.1e-30 103.9 0.5 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 ORY51925.1 - 1.9e-06 27.8 0.7 2.2e-06 27.6 0.7 1.1 1 0 0 1 1 1 1 PIG-P Gram_pos_anchor PF00746.21 ORY51925.1 - 4.5 7.3 8.7 0.46 10.5 1.9 2.1 2 0 0 2 2 2 0 LPXTG cell wall anchor motif TPR_2 PF07719.17 ORY51926.1 - 1e-22 78.4 6.3 0.013 15.5 0.0 10.2 9 2 1 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 ORY51926.1 - 1.3e-20 71.8 9.9 0.033 14.4 0.0 9.8 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_9 PF13371.6 ORY51926.1 - 5.1e-19 68.2 1.1 5.7e-06 26.4 0.0 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORY51926.1 - 2.5e-17 61.9 19.3 0.0048 16.7 0.0 10.1 11 1 0 11 11 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 ORY51926.1 - 3.5e-17 62.7 2.0 0.00019 21.9 0.1 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORY51926.1 - 2.6e-16 59.0 2.4 0.0039 16.9 0.0 7.8 7 3 1 8 8 8 4 TPR repeat TPR_14 PF13428.6 ORY51926.1 - 8.4e-15 54.2 1.9 0.0027 18.4 0.0 7.9 5 3 3 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORY51926.1 - 4.4e-13 49.3 4.2 0.026 14.8 0.0 8.0 7 2 1 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORY51926.1 - 5.4e-12 45.2 6.7 0.0012 19.1 0.1 6.8 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY51926.1 - 1.6e-07 31.9 0.8 0.85 10.3 0.0 5.4 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 ORY51926.1 - 5.4e-06 26.7 0.0 2.3 9.0 0.0 6.1 5 1 0 5 5 5 1 Tetratricopeptide repeat NARP1 PF12569.8 ORY51926.1 - 0.00039 19.5 0.5 0.75 8.6 0.1 2.7 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 ORY51926.1 - 0.00067 19.5 2.4 0.11 12.6 0.0 5.1 7 1 0 7 7 7 1 Tetratricopeptide repeat TPR_20 PF14561.6 ORY51926.1 - 0.00082 19.7 0.2 15 6.0 0.0 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY51926.1 - 0.0032 17.3 0.1 1.1 9.2 0.0 4.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 ORY51926.1 - 0.0037 16.5 0.9 0.39 9.9 0.1 3.5 4 1 0 4 4 4 1 Tetratricopeptide repeat RasGEF PF00617.19 ORY51927.1 - 2.3e-52 177.8 0.9 2.3e-52 177.8 0.9 2.9 3 1 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 ORY51927.1 - 1.5e-19 70.1 0.2 1.3e-18 67.2 0.0 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif Ead_Ea22 PF13935.6 ORY51927.1 - 0.12 13.0 5.1 0.12 13.1 2.6 2.1 1 1 1 2 2 2 0 Ead/Ea22-like protein CCDC24 PF15669.5 ORY51927.1 - 0.84 9.5 9.0 7.1 6.4 4.5 2.9 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 24 family CART PF06373.11 ORY51927.1 - 0.86 9.8 4.8 35 4.7 0.1 3.8 3 0 0 3 3 3 0 Cocaine and amphetamine regulated transcript protein (CART) DUF2482 PF10655.9 ORY51927.1 - 1.2 9.7 9.3 26 5.4 0.1 4.5 4 2 0 4 4 4 0 Hypothetical protein of unknown function (DUF2482) DUF5578 PF17741.1 ORY51928.1 - 1.6e-105 352.4 1.2 1.6e-105 352.4 1.2 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF5578) HNOB PF07700.15 ORY51928.1 - 0.072 13.0 0.1 11 6.0 0.0 3.1 2 1 0 2 2 2 0 Haem-NO-binding CRM1_repeat_3 PF18787.1 ORY51928.1 - 1.5 9.0 3.0 30 4.8 0.0 2.9 3 0 0 3 3 3 0 CRM1 / Exportin repeat 3 Ribosomal_L15e PF00827.17 ORY51929.1 - 2.6e-88 294.7 8.6 3e-88 294.6 8.6 1.0 1 0 0 1 1 1 1 Ribosomal L15 Acetyltransf_7 PF13508.7 ORY51930.1 - 3.1e-05 24.3 0.0 5.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY51930.1 - 0.0037 17.2 0.0 0.0072 16.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY51930.1 - 0.0088 16.3 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family REC114-like PF15165.6 ORY51930.1 - 0.074 12.8 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like AP1AR PF15745.5 ORY51930.1 - 0.074 12.7 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 AP-1 complex-associated regulatory protein ODAPH PF15848.5 ORY51930.1 - 0.26 11.7 7.0 0.87 10.1 6.8 1.9 2 0 0 2 2 2 0 Odontogenesis associated phosphoprotein Ribosomal_S6e PF01092.19 ORY51931.1 - 4.3e-57 191.5 0.1 7.5e-57 190.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Ribosomal_S17_N PF16205.5 ORY51932.1 - 8e-30 103.0 0.4 1.7e-29 102.0 0.4 1.6 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 ORY51932.1 - 6.6e-28 96.6 0.3 9.4e-28 96.1 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 Nbl1_Borealin_N PF10444.9 ORY51933.1 - 4.8 6.9 13.2 1.3 8.7 0.4 4.4 3 1 0 3 3 3 0 Nbl1 / Borealin N terminal SAM_Exu PF18609.1 ORY51933.1 - 8.5 6.5 12.4 14 5.8 3.5 4.5 3 1 0 3 3 3 0 Exuperantia SAM-like domain INCENP_ARK-bind PF03941.15 ORY51935.1 - 5.9e-15 54.9 0.6 9.4e-15 54.3 0.6 1.3 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region LSM PF01423.22 ORY51936.1 - 1.4e-17 63.1 1.6 1.7e-17 62.9 1.6 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 ORY51936.1 - 0.062 13.4 0.1 0.082 13.1 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Proteasome PF00227.26 ORY51937.1 - 1.5e-30 106.1 0.1 1.8e-30 105.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit XLF PF09302.11 ORY51938.1 - 0.00038 20.7 1.5 0.00062 20.0 0.0 2.0 2 0 0 2 2 2 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component PKcGMP_CC PF16808.5 ORY51938.1 - 0.017 15.0 3.0 0.051 13.4 3.0 1.7 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase gpUL132 PF11359.8 ORY51938.1 - 0.061 12.9 0.1 2.3 7.7 0.1 2.2 2 0 0 2 2 2 0 Glycoprotein UL132 ORC2 PF04084.14 ORY51939.1 - 2.4e-85 286.4 0.0 3.5e-85 285.8 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex subunit 2 PBP1_TM PF14812.6 ORY51939.1 - 8.6 6.8 10.0 17 5.9 2.3 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal YajC PF02699.15 ORY51940.1 - 0.013 15.4 5.5 0.087 12.7 1.3 2.3 1 1 1 2 2 2 0 Preprotein translocase subunit RNA_pol_Rpb1_1 PF04997.12 ORY51940.1 - 0.13 11.6 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 Cwf_Cwc_15 PF04889.12 ORY51940.1 - 0.98 9.1 9.3 0.14 11.9 2.5 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Cohesin_load PF10345.9 ORY51941.1 - 6.3e-14 51.4 2.6 1.1e-13 50.6 2.6 1.3 1 0 0 1 1 1 1 Cohesin loading factor TPR_12 PF13424.6 ORY51941.1 - 0.56 10.5 9.7 4.1 7.7 2.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat G-patch PF01585.23 ORY51942.1 - 2.6e-09 36.8 2.8 7e-05 22.6 0.0 3.5 2 1 0 2 2 2 2 G-patch domain R3H PF01424.22 ORY51942.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.8 2 0 0 2 2 2 0 R3H domain G-patch_2 PF12656.7 ORY51942.1 - 3.2 7.9 12.8 2.1 8.5 0.3 3.7 3 1 1 4 4 4 0 G-patch domain tRNA-synt_1c PF00749.21 ORY51943.1 - 1.1e-106 356.3 0.2 1.6e-106 355.8 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 ORY51943.1 - 3.7e-33 114.8 0.7 7.8e-33 113.8 0.5 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_bind PF01588.20 ORY51943.1 - 3.8e-29 100.6 0.1 7.5e-29 99.7 0.1 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C PF00043.25 ORY51943.1 - 0.00012 22.2 0.0 0.00036 20.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Amidohydro_1 PF01979.20 ORY51944.1 - 2.1e-08 33.9 0.0 4.3e-08 32.9 0.0 1.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 ORY51944.1 - 0.00017 21.5 0.0 0.00031 20.6 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase CsgE PF10627.9 ORY51946.1 - 0.12 12.7 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Curli assembly protein CsgE Yip1 PF04893.17 ORY51947.1 - 4.8e-18 65.5 13.3 8.2e-18 64.7 13.3 1.4 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 ORY51947.1 - 0.77 9.5 12.4 1.6 8.5 12.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) Pex26 PF07163.12 ORY51948.1 - 0.0012 18.2 0.1 0.0029 17.0 0.0 1.7 2 0 0 2 2 2 1 Pex26 protein ADP_ribosyl_GH PF03747.14 ORY51948.1 - 0.012 15.3 0.1 0.016 15.0 0.1 1.3 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase DUF4192 PF13830.6 ORY51948.1 - 0.037 14.1 2.0 0.21 11.6 3.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4192) DUF5427 PF10310.9 ORY51948.1 - 3.1 6.6 6.1 4.5 6.1 6.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) CDO_I PF05995.12 ORY51951.1 - 2e-50 170.4 0.0 1e-49 168.1 0.0 1.8 1 1 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 ORY51951.1 - 2.3e-08 33.7 0.0 3.2e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 PCO_ADO Usp PF00582.26 ORY51952.1 - 2.1e-25 89.9 0.1 2.9e-25 89.4 0.1 1.2 1 0 0 1 1 1 1 Universal stress protein family DUF5594 PF18057.1 ORY51952.1 - 0.079 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5594) DNA_photolyase PF00875.18 ORY51952.1 - 0.14 12.2 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 DNA photolyase Usp PF00582.26 ORY51953.1 - 4.2e-21 75.9 0.0 3.4e-20 73.0 0.0 2.0 1 1 0 1 1 1 1 Universal stress protein family Usp PF00582.26 ORY51954.1 - 4.8e-22 79.0 0.0 7.1e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family A_deaminase PF00962.22 ORY51955.1 - 1.9e-49 168.8 0.0 2.5e-30 105.9 0.1 2.2 2 0 0 2 2 2 2 Adenosine/AMP deaminase Mannosyl_trans3 PF11051.8 ORY51956.1 - 3.9e-35 121.6 0.1 1.8e-34 119.4 0.1 1.9 1 1 0 1 1 1 1 Mannosyltransferase putative WD40 PF00400.32 ORY51957.1 - 4.4e-47 157.1 18.9 1.3e-09 38.5 0.4 8.2 7 1 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 ORY51957.1 - 2.4e-18 66.2 9.1 4.1e-18 65.4 9.1 1.4 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 ORY51957.1 - 2.3e-14 53.5 0.1 0.052 13.9 0.0 5.3 3 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY51957.1 - 4.1e-05 22.4 1.2 0.21 10.2 0.0 3.5 1 1 3 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 ORY51957.1 - 4.8e-05 22.3 0.0 2.6 6.7 0.0 3.4 2 1 1 3 3 3 3 Nup133 N terminal like Ge1_WD40 PF16529.5 ORY51957.1 - 0.00021 20.4 0.1 3.6 6.5 0.0 4.2 2 2 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ORY51957.1 - 0.0048 16.3 0.0 7.5 5.8 0.0 3.5 3 1 1 4 4 4 1 WD40-like domain Jnk-SapK_ap_N PF09744.9 ORY51957.1 - 0.0057 16.9 3.1 0.011 15.9 3.1 1.4 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 APG6_N PF17675.1 ORY51957.1 - 0.044 14.3 4.4 0.088 13.3 4.4 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region Cytochrom_D1 PF02239.16 ORY51957.1 - 0.074 11.6 0.1 1.9 7.0 0.0 2.3 2 1 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 ORY51957.1 - 0.12 12.4 0.1 1.8e+02 2.2 0.0 4.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Abhydrolase_1 PF00561.20 ORY51958.1 - 3.9e-19 69.3 0.3 6.9e-13 48.8 0.2 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 ORY51958.1 - 1.3e-12 48.9 0.0 1.8e-12 48.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 ORY51958.1 - 4.2e-10 39.3 0.4 1e-09 38.0 0.4 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 ORY51958.1 - 3.5e-05 23.4 0.0 0.00099 18.7 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Palm_thioest PF02089.15 ORY51958.1 - 0.017 15.0 0.0 0.039 13.8 0.0 1.7 1 1 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_5 PF12695.7 ORY51958.1 - 0.023 14.5 0.0 6.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Thioesterase PF00975.20 ORY51958.1 - 0.028 14.5 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain UPF0227 PF05728.12 ORY51958.1 - 0.053 13.5 0.0 0.65 9.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Peptidase_S9 PF00326.21 ORY51958.1 - 0.071 12.6 0.3 0.25 10.8 0.0 2.0 2 1 0 2 2 2 0 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 ORY51958.1 - 0.077 12.9 0.1 0.33 10.8 0.1 2.0 1 1 0 1 1 1 0 Serine hydrolase LAMTOR5 PF16672.5 ORY51958.1 - 0.078 12.9 0.1 15 5.6 0.0 2.3 2 0 0 2 2 2 0 Ragulator complex protein LAMTOR5 BAAT_C PF08840.11 ORY51958.1 - 0.11 12.3 0.1 0.25 11.2 0.0 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal TrbI PF03743.14 ORY51959.1 - 0.027 14.3 0.4 0.052 13.4 0.4 1.4 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein Yip1 PF04893.17 ORY51960.1 - 1.3e-08 34.8 17.7 2.9e-08 33.6 17.7 1.6 1 1 0 1 1 1 1 Yip1 domain AICARFT_IMPCHas PF01808.18 ORY51961.1 - 7.4e-91 304.7 0.1 2.7e-90 302.8 0.0 2.0 3 0 0 3 3 3 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 ORY51961.1 - 9.9e-24 83.4 0.1 1.8e-23 82.5 0.1 1.5 1 0 0 1 1 1 1 MGS-like domain Ribosomal_S11 PF00411.19 ORY51961.1 - 0.047 14.1 0.4 0.18 12.3 0.4 2.0 1 0 0 1 1 1 0 Ribosomal protein S11 Usp PF00582.26 ORY51962.1 - 1.6e-26 93.5 0.1 2.1e-26 93.1 0.1 1.1 1 0 0 1 1 1 1 Universal stress protein family ABC_transp_aux PF09822.9 ORY51962.1 - 0.13 11.7 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 ABC-type uncharacterized transport system MFS_1 PF07690.16 ORY51963.1 - 3e-29 102.1 66.4 1.1e-17 64.0 31.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Pyridoxal_deC PF00282.19 ORY51964.1 - 3.7e-27 95.0 0.0 5.4e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SepSecS PF05889.13 ORY51964.1 - 0.019 13.6 0.0 0.089 11.5 0.0 2.0 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DHR-2 PF06920.13 ORY51965.1 - 3e-69 234.1 0.0 2.2e-38 132.2 0.0 3.1 2 1 0 2 2 2 2 Dock homology region 2 DOCK_N PF16172.5 ORY51965.1 - 1.5e-49 168.9 0.0 9.1e-48 163.1 0.0 2.2 1 1 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 ORY51965.1 - 7.4e-39 133.6 0.0 6e-38 130.6 0.0 2.2 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins SH3_2 PF07653.17 ORY51965.1 - 0.041 13.6 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.28 ORY51965.1 - 0.05 13.2 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 SH3 domain SH3_9 PF14604.6 ORY51965.1 - 0.15 12.0 0.0 0.39 10.6 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain MYCBPAP PF14646.6 ORY51966.1 - 1.3e-51 175.9 0.5 1.3e-51 175.9 0.5 1.9 2 0 0 2 2 2 1 MYCBP-associated protein family PI3_PI4_kinase PF00454.27 ORY51967.1 - 3.3e-54 184.4 0.0 6.9e-54 183.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 ORY51967.1 - 1.6e-32 113.1 0.9 2.9e-32 112.2 0.9 1.4 1 0 0 1 1 1 1 FAT domain UME PF08064.13 ORY51967.1 - 3.6e-24 84.6 0.0 3.4e-23 81.5 0.0 2.9 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.20 ORY51967.1 - 4.5e-16 58.4 0.1 1.1e-15 57.1 0.1 1.7 1 0 0 1 1 1 1 FATC domain AbiJ_NTD3 PF18860.1 ORY51967.1 - 0.012 15.2 0.1 0.5 9.9 0.0 3.1 3 0 0 3 3 3 0 AbiJ N-terminal domain 3 TAF6_C PF07571.13 ORY51967.1 - 0.038 14.3 0.1 5.4 7.4 0.0 3.8 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain TPR_14 PF13428.6 ORY51967.1 - 0.12 13.3 2.0 14 6.8 0.0 4.2 3 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY51967.1 - 0.17 12.0 0.9 49 4.4 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S17e PF00833.18 ORY51969.1 - 6.8e-62 206.8 0.2 7.8e-62 206.6 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 Vinculin PF01044.19 ORY51970.1 - 2.2e-46 158.7 22.0 3e-25 88.7 10.4 2.8 1 1 1 2 2 2 2 Vinculin family HHH_2 PF12826.7 ORY51970.1 - 0.044 13.9 0.1 0.16 12.0 0.1 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix motif Serine_rich PF08824.10 ORY51970.1 - 0.12 12.4 6.5 5.8 6.9 0.1 4.2 4 0 0 4 4 4 0 Serine rich protein interaction domain DUF1415 PF07209.12 ORY51970.1 - 0.13 12.0 0.2 0.52 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1415) DUF4763 PF15960.5 ORY51971.1 - 0.0021 17.4 6.2 0.0021 17.4 6.2 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4763) Ax_dynein_light PF10211.9 ORY51971.1 - 0.0075 16.2 4.3 0.0075 16.2 4.3 2.9 3 0 0 3 3 3 1 Axonemal dynein light chain Pex14_N PF04695.13 ORY51971.1 - 0.013 16.1 3.0 0.013 16.1 3.0 3.9 4 1 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PspB PF06667.12 ORY51971.1 - 0.26 11.4 1.8 0.83 9.8 1.8 1.9 1 0 0 1 1 1 0 Phage shock protein B Lectin_N PF03954.14 ORY51971.1 - 0.39 10.5 6.9 1.5 8.6 1.6 2.8 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Bromodomain PF00439.25 ORY51972.1 - 2.3e-37 126.9 2.5 9.6e-18 64.0 0.0 2.4 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 ORY51972.1 - 3.1e-12 46.4 0.0 6.6e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 BAH domain P_C PF06640.11 ORY51972.1 - 1.3 9.1 8.0 2.9 8.0 8.0 1.5 1 0 0 1 1 1 0 P protein C-terminus OTU PF02338.19 ORY51974.1 - 1.3e-25 90.4 0.2 1.3e-25 90.4 0.2 1.9 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 ORY51974.1 - 7.4e-05 22.3 5.2 7.6e-05 22.3 0.9 2.3 2 1 0 2 2 2 1 Peptidase C65 Otubain FlxA PF14282.6 ORY51974.1 - 0.015 15.3 0.9 0.015 15.3 0.9 2.8 3 0 0 3 3 3 0 FlxA-like protein GerA PF03323.13 ORY51974.1 - 0.081 11.4 1.4 0.097 11.1 1.4 1.1 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Striatin PF08232.12 ORY51974.1 - 0.14 12.8 14.2 0.3 11.7 14.1 1.6 1 1 0 1 1 1 0 Striatin family DDHD PF02862.17 ORY51974.1 - 0.37 10.9 2.8 0.45 10.6 2.8 1.3 1 0 0 1 1 1 0 DDHD domain Atg14 PF10186.9 ORY51974.1 - 2.4 7.2 8.5 3.4 6.7 8.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HMG_box_5 PF14887.6 ORY51974.1 - 3.8 7.5 10.7 1.1 9.3 0.3 3.2 2 1 1 3 3 3 0 HMG (high mobility group) box 5 AAA_13 PF13166.6 ORY51974.1 - 9.1 4.8 14.4 35 2.8 14.4 1.7 1 1 0 1 1 1 0 AAA domain ANAPC4 PF12896.7 ORY51975.1 - 4.4e-36 124.3 0.0 7.7e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 ORY51975.1 - 4.6e-07 30.0 0.0 1.2e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Antiterm PF03589.13 ORY51975.1 - 0.011 16.0 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 Antitermination protein NTF2 PF02136.20 ORY51976.1 - 3.1e-28 98.7 0.3 5.2e-28 98.0 0.3 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 ORY51976.1 - 2.8e-07 30.2 0.0 5.4e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4518 PF15008.6 ORY51976.1 - 0.0049 16.1 0.9 0.011 15.0 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4518) RRM_occluded PF16842.5 ORY51976.1 - 0.18 11.7 0.0 0.66 9.9 0.0 1.9 2 0 0 2 2 2 0 Occluded RNA-recognition motif ATP_sub_h PF10775.9 ORY51977.1 - 9.2e-18 64.0 0.5 1.5e-17 63.3 0.5 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h Ribonuc_L-PSP PF01042.21 ORY51978.1 - 3.5e-14 52.8 0.1 4.8e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP UQ_con PF00179.26 ORY51980.1 - 2.1e-32 111.7 0.1 2.1e-29 101.9 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme UEV PF05743.13 ORY51980.1 - 0.0048 16.8 0.0 0.009 15.9 0.0 1.5 1 0 0 1 1 1 1 UEV domain Ribosomal_S5_C PF03719.15 ORY51981.1 - 2.3e-25 87.8 0.6 9.1e-25 85.9 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 ORY51981.1 - 6e-22 77.4 4.7 9.8e-22 76.7 4.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Lipase_GDSL_2 PF13472.6 ORY51982.1 - 6.3e-09 36.5 0.1 5.5e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 ORY51982.1 - 4.1e-08 33.4 0.0 7.7e-08 32.5 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AAA_16 PF13191.6 ORY51983.1 - 0.00083 19.8 0.0 0.0012 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 ORY51983.1 - 0.0018 18.0 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY51983.1 - 0.0063 16.8 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 ORY51983.1 - 0.029 14.4 0.0 0.041 13.9 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 ORY51983.1 - 0.029 14.3 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.7 ORY51983.1 - 0.031 13.8 0.0 0.04 13.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 ORY51983.1 - 0.049 14.2 0.0 0.075 13.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter TniB PF05621.11 ORY51983.1 - 0.094 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein Zeta_toxin PF06414.12 ORY51983.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin PIF1 PF05970.14 ORY51983.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_29 PF13555.6 ORY51983.1 - 0.18 11.6 0.1 4.4 7.1 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 ORY51983.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 NTPase cobW PF02492.19 ORY51983.1 - 0.21 11.2 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 ORY51983.1 - 0.29 10.3 0.0 0.34 10.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Kinesin PF00225.23 ORY51985.1 - 3.7e-119 397.6 0.1 3.7e-119 397.6 0.1 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 ORY51985.1 - 3e-24 85.7 0.0 8.7e-24 84.2 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 ORY51985.1 - 0.0033 17.7 1.7 0.52 10.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain Kinesin_assoc PF16183.5 ORY51985.1 - 0.027 14.6 16.6 0.19 11.8 15.0 3.0 3 1 0 3 3 3 0 Kinesin-associated Macoilin PF09726.9 ORY51985.1 - 0.28 9.7 28.9 0.41 9.1 28.9 1.2 1 0 0 1 1 1 0 Macoilin family UPF0242 PF06785.11 ORY51985.1 - 0.34 11.0 32.7 1.3 9.1 25.3 2.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus WD40_alt PF14077.6 ORY51986.1 - 0.0048 16.7 0.1 0.0048 16.7 0.1 3.5 3 0 0 3 3 3 1 Alternative WD40 repeat motif CCDC92 PF14916.6 ORY51986.1 - 0.21 11.4 14.1 0.69 9.7 0.2 4.6 3 1 0 3 3 3 0 Coiled-coil domain of unknown function HALZ PF02183.18 ORY51986.1 - 0.27 11.5 39.5 1 9.6 0.6 8.4 7 2 0 7 7 7 0 Homeobox associated leucine zipper ZapB PF06005.12 ORY51986.1 - 0.87 10.1 68.8 1.6 9.3 3.6 7.8 5 1 1 6 6 6 0 Cell division protein ZapB FlaC_arch PF05377.11 ORY51986.1 - 1.4 9.4 44.3 0.59 10.6 0.4 8.6 6 2 5 11 11 11 0 Flagella accessory protein C (FlaC) DUF3800 PF12686.7 ORY51986.1 - 5.9 7.5 7.5 2e+03 -0.6 7.5 3.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) HLH PF00010.26 ORY51987.1 - 5e-10 39.2 0.4 6.5e-10 38.8 0.4 1.2 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GCV_T PF01571.21 ORY51988.1 - 1.4e-83 280.3 0.0 1.7e-83 280.0 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 ORY51988.1 - 9.7e-21 73.5 0.2 2.5e-20 72.2 0.2 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain CtaG_Cox11 PF04442.14 ORY51989.1 - 1.1e-59 200.8 0.2 1.2e-59 200.6 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 ATG27 PF09451.10 ORY51991.1 - 7.8e-24 84.9 0.0 9.2e-24 84.7 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 ORY51991.1 - 0.0027 17.8 0.1 1.5 8.9 0.1 2.1 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat V-ATPase_G PF03179.15 ORY51992.1 - 3.7e-31 107.8 8.4 4.2e-31 107.6 8.4 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 ORY51992.1 - 0.0024 18.0 4.8 0.0042 17.2 4.8 1.3 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) vATP-synt_E PF01991.18 ORY51992.1 - 0.0074 15.7 5.9 0.0093 15.4 5.9 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF3552 PF12072.8 ORY51992.1 - 0.067 12.6 8.1 0.059 12.8 7.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) GAS PF13851.6 ORY51993.1 - 0.00036 20.0 12.0 0.00046 19.6 6.7 2.8 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 ORY51993.1 - 0.00037 19.7 4.6 0.00086 18.5 4.6 1.6 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 ATG16 PF08614.11 ORY51993.1 - 0.00072 19.8 9.5 0.00072 19.8 9.5 2.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 ORY51993.1 - 0.0028 17.0 1.7 0.0061 16.0 1.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) PspA_IM30 PF04012.12 ORY51993.1 - 0.014 15.0 9.8 0.075 12.6 9.8 2.1 1 1 0 1 1 1 0 PspA/IM30 family CLZ PF16526.5 ORY51993.1 - 0.042 14.2 6.4 0.21 12.0 2.9 3.3 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels TACC_C PF05010.14 ORY51993.1 - 0.053 13.3 12.6 0.7 9.7 10.0 3.3 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF724 PF05266.14 ORY51993.1 - 0.06 13.2 15.0 0.049 13.5 2.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF724) GIT_CC PF16559.5 ORY51993.1 - 0.065 13.1 2.6 0.29 11.0 2.2 2.4 1 1 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor CorA PF01544.18 ORY51993.1 - 0.07 12.4 5.2 0.37 10.1 1.4 2.2 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF2730 PF10805.8 ORY51993.1 - 0.083 13.0 4.3 1.4 9.1 1.8 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) LMBR1 PF04791.16 ORY51993.1 - 0.16 10.9 2.8 0.24 10.3 2.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein HalX PF08663.10 ORY51993.1 - 0.18 12.2 2.9 0.61 10.5 0.7 3.0 1 1 2 3 3 3 0 HalX domain Trimer_CC PF08954.11 ORY51993.1 - 0.22 11.1 3.3 0.24 11.0 1.5 2.0 2 0 0 2 2 2 0 Trimerisation motif DUF848 PF05852.11 ORY51993.1 - 0.26 11.4 7.7 0.51 10.5 1.1 2.8 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) ADIP PF11559.8 ORY51993.1 - 0.28 11.3 21.7 0.025 14.7 6.2 3.3 1 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding PCRF PF03462.18 ORY51993.1 - 0.33 10.8 9.4 1 9.2 2.3 2.8 1 1 1 2 2 2 0 PCRF domain YabA PF06156.13 ORY51993.1 - 0.37 11.5 10.5 0.17 12.5 2.9 3.6 2 1 1 3 3 3 0 Initiation control protein YabA Baculo_PEP_C PF04513.12 ORY51993.1 - 0.48 10.5 10.6 0.13 12.3 4.2 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4600 PF15372.6 ORY51993.1 - 0.75 10.2 7.4 1.6 9.2 0.9 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4600) FUSC PF04632.12 ORY51993.1 - 1.3 7.4 5.2 1.9 6.9 5.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fib_alpha PF08702.10 ORY51993.1 - 1.5 9.0 10.9 0.5 10.5 3.0 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family PH_12 PF16457.5 ORY51993.1 - 2.3 8.8 5.4 0.93 10.0 0.4 2.8 4 0 0 4 4 2 0 Pleckstrin homology domain GAT PF03127.14 ORY51993.1 - 2.8 8.3 8.1 6.2 7.2 2.7 3.0 1 1 0 2 2 2 0 GAT domain DASH_Spc34 PF08657.10 ORY51993.1 - 3.7 7.3 18.3 0.72 9.6 0.1 3.8 2 1 1 4 4 4 0 DASH complex subunit Spc34 Exonuc_VII_L PF02601.15 ORY51993.1 - 4.3 6.8 11.6 16 4.9 9.8 2.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 ORY51993.1 - 5.6 7.0 16.2 1.8 8.6 1.0 4.0 2 1 3 5 5 4 0 Protein of unknown function (DUF1664) ZapB PF06005.12 ORY51993.1 - 6.2 7.3 12.5 12 6.4 5.0 3.8 1 1 2 3 3 3 0 Cell division protein ZapB DOG1 PF14144.6 ORY51993.1 - 7 7.0 6.3 2.4 8.4 0.2 3.2 4 0 0 4 4 4 0 Seed dormancy control DUF948 PF06103.11 ORY51993.1 - 8.9 6.7 11.4 6.7 7.1 0.2 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) OmpH PF03938.14 ORY51993.1 - 10 6.5 10.2 0.34 11.2 1.9 2.5 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Lebercilin PF15619.6 ORY51994.1 - 3.1e-20 72.7 26.5 5e-20 72.0 26.5 1.3 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease fn3 PF00041.21 ORY51994.1 - 4.7e-13 49.3 2.3 1.8e-06 28.2 0.3 4.5 4 0 0 4 4 4 2 Fibronectin type III domain TPR_MLP1_2 PF07926.12 ORY51994.1 - 0.017 15.2 16.7 0.064 13.3 9.9 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N PF09744.9 ORY51994.1 - 0.24 11.6 28.3 0.2 11.9 15.4 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF4407 PF14362.6 ORY51994.1 - 1.5 8.1 9.5 1.8 7.8 8.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Csm1_N PF18504.1 ORY51994.1 - 5.5 7.4 15.6 2.7 8.4 1.3 3.7 2 2 1 3 3 3 0 Csm1 N-terminal domain LMBR1 PF04791.16 ORY51994.1 - 7.4 5.3 4.8 11 4.8 4.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein IFT57 PF10498.9 ORY51995.1 - 5.8e-122 407.1 0.7 6.6e-122 407.0 0.7 1.0 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 DUF1349 PF07081.11 ORY51995.1 - 0.0019 18.0 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) ZapB PF06005.12 ORY51995.1 - 0.0022 18.4 1.0 0.0022 18.4 1.0 2.5 2 0 0 2 2 2 1 Cell division protein ZapB WEMBL PF05701.11 ORY51995.1 - 0.0051 15.6 5.6 0.007 15.1 5.6 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Erp_C PF06780.11 ORY51995.1 - 0.0059 16.6 3.6 1.7 8.7 0.6 2.6 1 1 1 2 2 2 2 Erp protein C-terminus Spc7 PF08317.11 ORY51995.1 - 0.0071 15.3 6.4 0.011 14.7 6.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF489 PF04356.12 ORY51995.1 - 0.011 15.8 4.1 0.021 14.9 3.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF489) GAS PF13851.6 ORY51995.1 - 0.011 15.0 8.2 0.012 14.9 2.1 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding EzrA PF06160.12 ORY51995.1 - 0.021 13.0 7.9 0.48 8.5 1.0 2.1 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA HrpB7 PF09486.10 ORY51995.1 - 0.025 15.0 0.5 0.69 10.3 0.2 2.4 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) Seryl_tRNA_N PF02403.22 ORY51995.1 - 0.027 14.7 2.2 0.027 14.7 2.2 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Lebercilin PF15619.6 ORY51995.1 - 0.031 13.9 7.3 0.058 13.1 7.3 1.4 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Snapin_Pallidin PF14712.6 ORY51995.1 - 0.041 14.3 1.1 0.041 14.3 1.1 3.1 1 1 2 3 3 3 0 Snapin/Pallidin CENP-F_leu_zip PF10473.9 ORY51995.1 - 0.047 13.7 10.0 0.11 12.5 8.6 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-Q PF13094.6 ORY51995.1 - 0.047 13.9 4.9 0.16 12.1 4.9 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Prefoldin_2 PF01920.20 ORY51995.1 - 0.053 13.5 6.5 0.19 11.7 3.2 2.8 1 1 1 2 2 2 0 Prefoldin subunit TMF_DNA_bd PF12329.8 ORY51995.1 - 0.069 13.1 0.5 0.069 13.1 0.5 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 ORY51995.1 - 0.081 13.0 7.6 0.48 10.5 4.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF641 PF04859.12 ORY51995.1 - 0.31 11.4 4.8 0.15 12.4 1.7 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TMPIT PF07851.13 ORY51995.1 - 0.89 8.7 7.7 1 8.5 5.5 1.7 1 1 1 2 2 2 0 TMPIT-like protein NPV_P10 PF05531.12 ORY51995.1 - 1.1 9.7 5.9 0.33 11.5 0.5 2.8 3 1 1 4 4 2 0 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 ORY51995.1 - 1.9 8.9 5.5 9.5 6.7 0.6 3.0 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels APG6_N PF17675.1 ORY51995.1 - 3 8.4 11.1 7.2 7.1 11.1 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF16 PF01519.16 ORY51995.1 - 3.7 8.1 10.8 0.98 9.9 6.2 2.3 2 1 0 2 2 2 0 Protein of unknown function DUF16 DUF2205 PF10224.9 ORY51995.1 - 3.7 7.6 9.2 5.2 7.2 6.6 2.4 1 1 1 2 2 2 0 Short coiled-coil protein PPV_E1_N PF00524.18 ORY51995.1 - 5.5 7.4 9.0 2.4 8.6 1.5 2.3 1 1 1 2 2 2 0 E1 Protein, N terminal domain RFC1 PF08519.12 ORY51996.1 - 3e-53 180.2 0.1 1.2e-50 171.8 0.0 2.7 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 ORY51996.1 - 1.4e-15 57.4 0.0 3.4e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 ORY51996.1 - 2.3e-13 50.7 0.2 6.3e-13 49.3 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 ORY51996.1 - 1e-08 35.3 1.3 1.8e-08 34.5 0.1 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 ORY51996.1 - 2e-07 31.4 0.0 5.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 ORY51996.1 - 3.5e-06 26.9 0.0 9.1e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 ORY51996.1 - 3.3e-05 23.7 0.0 7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 ORY51996.1 - 8.7e-05 22.6 0.1 0.00024 21.1 0.1 1.8 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 ORY51996.1 - 0.00028 20.9 0.6 0.058 13.3 0.1 2.3 1 1 1 2 2 2 1 NTPase Sigma54_activ_2 PF14532.6 ORY51996.1 - 0.00039 20.6 0.4 0.0032 17.6 0.0 2.7 3 1 0 3 3 3 1 Sigma-54 interaction domain TniB PF05621.11 ORY51996.1 - 0.00053 19.4 0.1 0.086 12.2 0.1 2.5 1 1 0 1 1 1 1 Bacterial TniB protein RuvB_N PF05496.12 ORY51996.1 - 0.0012 18.6 0.0 0.0028 17.4 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 ORY51996.1 - 0.0012 19.4 0.0 0.0035 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY51996.1 - 0.0015 18.9 0.1 0.0077 16.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 ORY51996.1 - 0.0024 17.6 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 ORY51996.1 - 0.0073 16.0 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_2 PF07724.14 ORY51996.1 - 0.0083 16.3 0.1 0.019 15.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) PTCB-BRCT PF12738.7 ORY51996.1 - 0.012 15.5 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain AAA_33 PF13671.6 ORY51996.1 - 0.018 15.2 0.0 0.048 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 ORY51996.1 - 0.018 14.9 0.0 0.31 10.9 0.0 2.5 1 1 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.12 ORY51996.1 - 0.024 13.9 0.1 0.061 12.6 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 ORY51996.1 - 0.039 14.3 0.2 0.35 11.3 0.0 2.7 2 1 0 2 2 1 0 RNA helicase AAA_5 PF07728.14 ORY51996.1 - 0.044 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 ORY51996.1 - 0.071 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ORY51996.1 - 0.092 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 ORY51996.1 - 0.11 12.9 0.4 1.1 9.6 0.4 2.4 1 1 0 1 1 1 0 AAA domain TPR_17 PF13431.6 ORY51997.1 - 0.042 14.2 1.3 0.62 10.6 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 ORY51997.1 - 0.049 13.7 8.8 0.29 11.2 0.3 4.6 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 ORY51997.1 - 0.18 11.9 5.1 63 3.9 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 ORY51997.1 - 0.23 11.8 7.1 0.67 10.3 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY51997.1 - 2.9 8.9 11.5 33 5.7 0.1 6.1 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 ORY51997.1 - 5.4 7.0 11.1 1.9 8.5 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Tubulin_3 PF14881.6 ORY51998.1 - 1.4e-34 119.4 0.0 3.3e-34 118.1 0.0 1.6 2 0 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.9 ORY51998.1 - 5e-27 94.6 0.1 2.6e-26 92.3 0.0 2.1 2 1 1 3 3 3 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 ORY51998.1 - 9e-05 22.8 0.0 0.019 15.2 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain TPR_6 PF13174.6 ORY51999.1 - 0.015 15.9 0.4 65 4.5 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY51999.1 - 0.017 15.4 1.9 0.94 9.8 0.4 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.20 ORY51999.1 - 0.056 13.7 0.1 5.8 7.4 0.1 2.7 2 0 0 2 2 2 0 PPR repeat ANAPC3 PF12895.7 ORY51999.1 - 0.062 13.5 0.3 5 7.4 0.1 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Caskin-tail PF16632.5 ORY51999.1 - 0.11 12.9 0.5 0.57 10.6 0.0 2.5 2 0 0 2 2 2 0 C-terminal region of Caskin TPR_1 PF00515.28 ORY51999.1 - 0.16 11.9 0.2 1.5 8.7 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2012 PF09430.10 ORY52000.1 - 3.5e-20 72.3 0.0 5.9e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 ORY52000.1 - 0.072 13.4 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Diphthamide_syn PF01866.17 ORY52001.1 - 1.1e-55 189.3 0.0 1.4e-55 188.9 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Methyltransf_28 PF02636.17 ORY52002.1 - 1.8e-73 247.4 0.0 2.1e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ribosomal_L15e PF00827.17 ORY52003.1 - 2.6e-88 294.7 8.6 3e-88 294.6 8.6 1.0 1 0 0 1 1 1 1 Ribosomal L15 Y_phosphatase PF00102.27 ORY52004.1 - 2.4e-124 413.5 0.0 2.4e-68 230.2 0.9 4.2 3 1 0 3 3 3 3 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 ORY52004.1 - 1.6e-08 34.8 0.2 0.00042 20.4 0.0 2.3 2 0 0 2 2 2 2 Tyrosine phosphatase family DSPc PF00782.20 ORY52004.1 - 4.4e-07 29.8 0.1 0.017 14.9 0.0 2.7 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 ORY52004.1 - 9.8e-06 25.8 0.1 0.09 12.9 0.0 2.7 2 0 0 2 2 2 2 Inositol hexakisphosphate Sacchrp_dh_NADP PF03435.18 ORY52005.1 - 1.4e-13 51.3 0.0 3.3e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain tRNA-synt_1e PF01406.19 ORY52006.1 - 3.1e-127 424.1 2.6 3.1e-127 424.1 2.6 1.9 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 ORY52006.1 - 9e-05 21.4 1.0 0.017 13.9 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ORY52006.1 - 0.0037 15.6 0.0 0.014 13.6 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.11 ORY52006.1 - 0.012 16.1 0.0 0.012 16.1 0.0 2.5 3 0 0 3 3 3 0 DALR domain Peptidase_M24 PF00557.24 ORY52006.1 - 0.014 15.1 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Metallopeptidase family M24 tRNA-synt_1c PF00749.21 ORY52006.1 - 0.058 12.3 0.0 0.058 12.3 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain DUF3510 PF12022.8 ORY52006.1 - 0.11 12.9 0.1 8.3 6.8 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF3510) LRR_4 PF12799.7 ORY52007.1 - 2.7e-32 110.2 34.8 3.3e-07 30.5 1.4 7.6 2 2 3 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY52007.1 - 1.7e-21 75.7 31.1 9.8e-07 28.4 4.3 6.5 3 2 4 8 8 8 8 Leucine rich repeat LRR_9 PF14580.6 ORY52007.1 - 3.9e-19 68.8 14.3 3.4e-07 29.9 3.7 3.4 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 ORY52007.1 - 0.0032 17.8 21.2 20 6.2 0.0 8.9 8 1 1 9 9 9 1 Leucine Rich Repeat LRR_6 PF13516.6 ORY52007.1 - 0.01 15.8 27.0 3.5 7.9 0.0 9.4 9 1 2 11 11 11 0 Leucine Rich repeat Complex1_LYR_2 PF13233.6 ORY52008.1 - 1.7e-09 38.3 0.1 2.3e-09 37.8 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like EF-hand_1 PF00036.32 ORY52010.1 - 2.9e-31 104.7 14.9 4.2e-09 35.3 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 ORY52010.1 - 3.8e-30 104.2 10.8 1.8e-15 57.1 2.5 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 ORY52010.1 - 1.5e-24 83.8 11.9 3.6e-08 32.7 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 ORY52010.1 - 8.3e-19 67.2 15.1 7.1e-11 41.8 0.9 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 ORY52010.1 - 1.4e-13 49.7 15.2 0.0011 18.3 1.6 4.5 4 1 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 ORY52010.1 - 1e-11 45.0 0.8 7.8e-05 22.9 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 ORY52010.1 - 3.5e-08 33.3 6.7 0.00016 21.5 0.4 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 ORY52010.1 - 0.00033 20.6 1.9 0.056 13.4 0.0 3.5 1 1 2 4 4 4 1 Caleosin related protein EF-hand_14 PF17959.1 ORY52010.1 - 0.0026 18.1 1.7 0.093 13.1 0.2 2.5 1 1 1 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 ORY52010.1 - 0.0098 16.2 4.6 0.33 11.3 0.6 2.3 1 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region PhetRS_B1 PF18262.1 ORY52010.1 - 0.021 15.0 0.7 0.058 13.6 0.7 1.7 1 0 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain DUF1296 PF06972.11 ORY52010.1 - 0.029 14.5 0.5 1.7 8.9 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1296) HTH_40 PF14493.6 ORY52010.1 - 0.12 12.8 0.7 3.3 8.2 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain SurA_N_2 PF13623.6 ORY52010.1 - 0.13 12.1 2.2 3.5 7.5 0.2 2.5 2 1 0 2 2 2 0 SurA N-terminal domain EF-hand_11 PF08976.11 ORY52010.1 - 0.15 13.0 0.6 4.6 8.2 0.1 2.1 1 1 1 2 2 2 0 EF-hand domain SMC_N PF02463.19 ORY52011.1 - 1e-64 218.0 41.8 3.1e-63 213.1 41.8 3.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 ORY52011.1 - 4.2e-25 88.3 0.1 1.5e-24 86.5 0.1 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 ORY52011.1 - 6.6e-16 59.0 0.2 2.1e-07 31.1 0.0 3.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 ORY52011.1 - 1.1e-14 55.4 0.1 1.1e-14 55.4 0.1 6.9 2 2 2 4 4 4 1 AAA domain AAA_15 PF13175.6 ORY52011.1 - 2.2e-09 37.5 29.6 2.2e-09 37.5 29.6 4.0 2 2 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 ORY52011.1 - 1.4e-05 24.7 0.0 3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain TMF_DNA_bd PF12329.8 ORY52011.1 - 0.0087 16.0 5.5 0.0087 16.0 5.5 12.4 8 5 5 14 14 14 2 TATA element modulatory factor 1 DNA binding AAA_22 PF13401.6 ORY52011.1 - 0.023 14.9 0.3 5.4 7.3 0.0 3.9 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.27 ORY52011.1 - 0.14 12.6 0.0 0.14 12.6 0.0 5.9 4 2 0 5 5 5 0 ABC transporter DUF4485 PF14846.6 ORY52011.1 - 4.1 7.5 13.3 0.26 11.4 0.8 4.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4485) Slx4 PF09494.10 ORY52012.1 - 5.8e-14 51.8 0.0 1.5e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 Slx4 endonuclease zf-C2H2_4 PF13894.6 ORY52012.1 - 0.006 17.3 0.9 2.5 9.2 0.0 3.0 2 0 0 2 2 2 1 C2H2-type zinc finger ATP11 PF06644.11 ORY52012.1 - 0.016 15.0 1.3 0.016 15.0 1.3 3.9 3 2 1 4 4 4 0 ATP11 protein AdHead_fibreRBD PF16812.5 ORY52012.1 - 0.017 14.9 0.0 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 C-terminal head domain of the fowl adenovirus type 1 long fibre Zn-C2H2_12 PF18112.1 ORY52012.1 - 0.1 13.1 2.1 8.3 7.0 0.2 2.8 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Rho_N PF07498.12 ORY52012.1 - 0.13 12.2 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain zf-C3HC4_3 PF13920.6 ORY52012.1 - 0.14 12.0 0.1 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UBZ_FAAP20 PF15750.5 ORY52012.1 - 0.16 12.0 5.5 0.29 11.1 1.5 2.5 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-C2H2_9 PF16293.5 ORY52012.1 - 2.9 7.8 5.2 6.9 6.6 0.1 3.3 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) Prefoldin_2 PF01920.20 ORY52013.1 - 1.4e-25 89.3 10.6 2e-25 88.8 10.6 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 ORY52013.1 - 0.00039 20.4 4.4 0.00064 19.7 4.4 1.3 1 0 0 1 1 1 1 Prefoldin subunit DUF1351 PF07083.11 ORY52013.1 - 0.004 16.9 3.0 0.004 16.9 3.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1351) Macoilin PF09726.9 ORY52013.1 - 0.0042 15.7 10.6 0.0045 15.6 10.6 1.0 1 0 0 1 1 1 1 Macoilin family ADIP PF11559.8 ORY52013.1 - 0.0044 17.1 1.1 0.0044 17.1 1.1 2.0 1 1 1 2 2 2 1 Afadin- and alpha -actinin-Binding Tup_N PF08581.10 ORY52013.1 - 0.0058 16.9 10.8 1.6 9.1 0.1 3.2 2 1 1 3 3 3 2 Tup N-terminal TMF_TATA_bd PF12325.8 ORY52013.1 - 0.019 15.2 10.0 0.19 12.0 2.2 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding End3 PF12761.7 ORY52013.1 - 0.024 14.8 8.8 0.034 14.3 8.8 1.2 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 DUF1192 PF06698.11 ORY52013.1 - 0.028 14.4 1.4 0.081 13.0 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) PspA_IM30 PF04012.12 ORY52013.1 - 0.045 13.3 12.8 0.13 11.8 12.8 1.6 1 1 0 1 1 1 0 PspA/IM30 family Occludin_ELL PF07303.13 ORY52013.1 - 0.058 14.1 8.0 1.1 10.0 0.6 2.1 2 0 0 2 2 2 0 Occludin homology domain Syntaxin_2 PF14523.6 ORY52013.1 - 0.077 13.4 9.7 0.28 11.6 2.8 2.4 1 1 1 2 2 2 0 Syntaxin-like protein PHM7_cyt PF14703.6 ORY52013.1 - 0.079 13.2 7.7 0.14 12.4 7.7 1.4 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter APG6_N PF17675.1 ORY52013.1 - 0.16 12.5 13.6 0.46 11.0 11.2 2.0 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF724 PF05266.14 ORY52013.1 - 0.16 11.8 11.3 0.21 11.4 3.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) EzrA PF06160.12 ORY52013.1 - 0.22 9.7 14.7 0.083 11.1 7.3 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA HalX PF08663.10 ORY52013.1 - 0.23 11.8 3.1 0.47 10.8 0.7 2.3 2 0 0 2 2 2 0 HalX domain Seryl_tRNA_N PF02403.22 ORY52013.1 - 0.24 11.6 12.4 0.84 9.9 1.9 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF16 PF01519.16 ORY52013.1 - 0.49 10.9 9.7 4.5 7.8 9.8 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF2203 PF09969.9 ORY52013.1 - 0.51 11.1 4.3 0.72 10.6 3.1 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Spc24 PF08286.11 ORY52013.1 - 0.65 10.3 10.7 2.3 8.5 2.1 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4407 PF14362.6 ORY52013.1 - 0.76 9.1 6.5 1 8.7 6.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FlaC_arch PF05377.11 ORY52013.1 - 0.84 10.1 11.5 6.8 7.2 2.0 3.0 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 ORY52013.1 - 1 9.4 16.1 0.55 10.3 4.0 2.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF641 PF04859.12 ORY52013.1 - 1.1 9.6 11.2 2.4 8.5 5.3 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DivIC PF04977.15 ORY52013.1 - 1.1 9.1 15.7 3.1 7.6 3.5 3.0 2 2 0 2 2 2 0 Septum formation initiator HIP1_clath_bdg PF16515.5 ORY52013.1 - 1.1 9.9 11.6 1.5 9.5 2.4 2.1 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 YabA PF06156.13 ORY52013.1 - 1.2 9.8 11.0 2.7 8.7 2.1 2.1 1 1 1 2 2 2 0 Initiation control protein YabA DUF4795 PF16043.5 ORY52013.1 - 1.6 8.3 12.4 0.47 10.0 2.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) bZIP_1 PF00170.21 ORY52013.1 - 2.4 8.3 14.4 7.2 6.8 3.5 3.4 2 2 1 3 3 3 0 bZIP transcription factor Prefoldin PF02996.17 ORY52013.1 - 3.3 7.7 13.7 1.8e+02 2.1 13.7 2.5 1 1 0 1 1 1 0 Prefoldin subunit DUF1664 PF07889.12 ORY52013.1 - 3.4 7.7 7.7 3.2 7.8 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Rho_Binding PF08912.11 ORY52013.1 - 5.5 7.9 15.8 1.2 10.1 3.7 2.2 2 0 0 2 2 2 0 Rho Binding Csm1_N PF18504.1 ORY52013.1 - 7.7 6.9 14.3 2.2 8.7 1.7 3.0 2 2 1 3 3 3 0 Csm1 N-terminal domain Fib_alpha PF08702.10 ORY52013.1 - 9.3 6.4 11.8 1.4e+02 2.6 11.8 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Ribosomal_L3 PF00297.22 ORY52014.1 - 7.8e-155 515.4 11.5 8.9e-155 515.2 11.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 PDCD2_C PF04194.13 ORY52015.1 - 9.6e-35 120.2 2.9 9.6e-35 120.2 2.9 2.5 2 1 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.18 ORY52015.1 - 1.2e-07 31.6 8.7 1.2e-07 31.6 8.7 3.7 4 0 0 4 4 4 1 MYND finger HECT PF00632.25 ORY52016.1 - 1.6e-83 280.7 0.0 2.7e-83 280.0 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) BH4 PF02180.17 ORY52016.1 - 0.53 10.1 0.0 0.53 10.1 0.0 2.1 2 0 0 2 2 2 0 Bcl-2 homology region 4 ThiF PF00899.21 ORY52017.1 - 2.6e-67 226.8 0.0 3.8e-67 226.2 0.0 1.2 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 ORY52017.1 - 9.3e-13 48.7 2.0 6.8e-09 36.0 0.1 2.6 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 ORY52017.1 - 1.7e-11 44.6 0.3 4.1e-11 43.3 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 ORY52017.1 - 0.00097 19.5 0.1 0.0048 17.3 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding Big_9 PF17963.1 ORY52017.1 - 0.011 16.4 0.4 0.031 15.0 0.4 1.8 1 0 0 1 1 1 0 Bacterial Ig domain Cadherin_5 PF17892.1 ORY52017.1 - 0.086 12.8 0.4 0.3 11.1 0.1 2.0 2 0 0 2 2 2 0 Cadherin-like domain Shikimate_DH PF01488.20 ORY52017.1 - 0.088 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DNA_primase_S PF01896.19 ORY52018.1 - 4.4e-59 199.5 0.3 6.8e-59 198.9 0.3 1.3 1 0 0 1 1 1 1 DNA primase small subunit STIL_N PF15253.6 ORY52018.1 - 0.085 11.8 0.5 0.13 11.2 0.5 1.2 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus Spt5_N PF11942.8 ORY52018.1 - 0.12 13.4 9.1 0.27 12.2 9.1 1.6 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Cwf_Cwc_15 PF04889.12 ORY52020.1 - 0.13 12.0 8.7 0.45 10.2 8.7 1.9 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 ORY52020.1 - 3.5 6.9 16.8 8.7 5.6 16.8 1.6 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.12 ORY52020.1 - 5.8 5.0 13.4 13 3.9 13.4 1.5 1 0 0 1 1 1 0 Nop14-like family zf-C2H2_aberr PF17017.5 ORY52021.1 - 2e-05 24.8 0.4 0.0077 16.4 0.1 2.5 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2 PF00096.26 ORY52021.1 - 0.034 14.6 0.3 0.034 14.6 0.3 3.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY52021.1 - 0.49 11.4 0.2 0.49 11.4 0.2 4.3 5 0 0 5 5 5 0 C2H2-type zinc finger DUF2071 PF09844.9 ORY52021.1 - 0.91 9.1 7.1 2.6 7.6 7.1 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (COG2071) MoCF_biosynth PF00994.24 ORY52022.1 - 9.2e-55 184.3 0.5 2.2e-33 114.9 0.2 2.5 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 ORY52022.1 - 3.4e-37 127.6 4.4 6e-37 126.8 4.4 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 ORY52022.1 - 4.8e-12 45.9 0.4 2.4e-11 43.6 0.0 2.4 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) MspA PF09203.11 ORY52022.1 - 0.016 15.1 0.4 0.089 12.6 0.4 2.2 1 1 0 1 1 1 0 MspA DUF3331 PF11811.8 ORY52023.1 - 0.041 13.7 0.1 0.052 13.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3331) zf-CCHC PF00098.23 ORY52025.1 - 5.7e-06 26.2 1.3 5.7e-06 26.2 1.3 2.1 3 0 0 3 3 3 1 Zinc knuckle Retrotran_gag_2 PF14223.6 ORY52025.1 - 0.0047 16.6 0.1 0.0093 15.6 0.1 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type MFS_1 PF07690.16 ORY52026.1 - 7.2e-07 28.4 3.6 7.2e-07 28.4 3.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Usp PF00582.26 ORY52027.1 - 9.6e-24 84.5 0.0 1.3e-23 84.0 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Cypo_polyhedrin PF05865.11 ORY52027.1 - 0.025 14.0 0.1 0.03 13.7 0.1 1.1 1 0 0 1 1 1 0 Cypovirus polyhedrin protein ABC_transp_aux PF09822.9 ORY52027.1 - 0.045 13.2 0.0 0.094 12.2 0.0 1.5 1 1 1 2 2 2 0 ABC-type uncharacterized transport system Usp PF00582.26 ORY52028.1 - 2.6e-21 76.6 0.1 8.2e-21 75.0 0.1 1.7 1 1 0 1 1 1 1 Universal stress protein family Usp PF00582.26 ORY52029.1 - 2.7e-11 44.1 0.0 4.3e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family ubiquitin PF00240.23 ORY52030.1 - 5.3e-05 22.9 0.0 0.0018 18.0 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin family LapA_dom PF06305.11 ORY52030.1 - 0.88 9.4 0.0 0.88 9.4 0.0 2.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain FoP_duplication PF13865.6 ORY52031.1 - 0.47 11.0 11.0 0.74 10.4 11.0 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Gly_transf_sug PF04488.15 ORY52032.1 - 3.9e-13 49.9 0.0 5.9e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 ORY52032.1 - 0.0018 17.6 0.2 0.0045 16.3 0.0 1.6 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain Phageshock_PspD PF09584.10 ORY52033.1 - 0.24 11.5 3.7 0.82 9.7 3.7 1.9 1 0 0 1 1 1 0 Phage shock protein PspD (Phageshock_PspD) MFS_1 PF07690.16 ORY52034.1 - 8e-30 103.9 61.9 6e-23 81.3 26.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gly_transf_sug PF04488.15 ORY52034.1 - 3.1e-15 56.6 0.0 1e-11 45.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase sugar-binding region containing DXD motif MFS_1_like PF12832.7 ORY52034.1 - 0.0031 16.5 7.5 0.0031 16.5 7.5 2.3 1 1 0 2 2 2 1 MFS_1 like family Caps_synth PF05704.12 ORY52034.1 - 0.062 12.7 0.3 0.094 12.1 0.3 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.7 ORY52034.1 - 0.13 11.6 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain CsgE PF10627.9 ORY52035.1 - 0.12 12.7 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Curli assembly protein CsgE TPK_catalytic PF04263.16 ORY52036.1 - 1.7e-36 124.9 0.0 2.6e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 ORY52036.1 - 1.5e-14 53.4 0.0 3.4e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Rhomboid PF01694.22 ORY52037.1 - 4.5e-10 39.7 9.8 2.9e-08 33.9 9.8 3.0 1 1 0 1 1 1 1 Rhomboid family Chromate_transp PF02417.15 ORY52037.1 - 0.002 18.3 3.7 0.0085 16.2 3.7 2.1 1 1 0 1 1 1 1 Chromate transporter AMP-binding PF00501.28 ORY52038.1 - 1.7e-76 257.5 0.1 2.1e-76 257.2 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY52038.1 - 2.2e-20 73.4 0.0 6.6e-20 71.9 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Usp PF00582.26 ORY52039.1 - 1.7e-21 77.2 0.1 4.8e-21 75.7 0.1 1.6 1 1 0 1 1 1 1 Universal stress protein family Usp PF00582.26 ORY52040.1 - 9.4e-24 84.5 0.0 1.3e-23 84.1 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Cypo_polyhedrin PF05865.11 ORY52040.1 - 0.025 14.0 0.1 0.03 13.7 0.1 1.1 1 0 0 1 1 1 0 Cypovirus polyhedrin protein ABC_transp_aux PF09822.9 ORY52040.1 - 0.043 13.3 0.0 0.096 12.1 0.0 1.6 1 1 1 2 2 2 0 ABC-type uncharacterized transport system Usp PF00582.26 ORY52041.1 - 1.3e-23 84.1 0.0 4.4e-23 82.4 0.0 1.7 1 1 0 1 1 1 1 Universal stress protein family Usp PF00582.26 ORY52042.1 - 3.8e-20 72.8 0.2 1.3e-19 71.1 0.2 1.7 1 1 0 1 1 1 1 Universal stress protein family NUDIX PF00293.28 ORY52043.1 - 2e-16 60.2 0.0 4.4e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 ORY52043.1 - 5.4e-06 25.9 0.7 1e-05 25.1 0.7 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Ank_2 PF12796.7 ORY52043.1 - 0.00013 22.4 0.2 0.00035 21.1 0.2 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) NUDIX-like PF09296.11 ORY52043.1 - 0.002 18.8 0.0 0.0089 16.7 0.1 2.2 2 0 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain Ank_4 PF13637.6 ORY52043.1 - 0.032 14.8 0.0 0.12 13.0 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeats (many copies) 3HCDH_RFF PF18321.1 ORY52043.1 - 3.6 8.1 6.8 4.5 7.8 4.3 2.3 1 1 1 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain RasGEF PF00617.19 ORY52044.1 - 2e-17 64.0 2.9 8.3e-17 61.9 0.2 2.4 2 0 0 2 2 2 1 RasGEF domain DUF572 PF04502.13 ORY52044.1 - 1.4 8.5 10.0 4.5 6.8 3.6 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) DNA_binding_1 PF01035.20 ORY52045.1 - 6.5e-21 74.2 0.0 1.2e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Homeodomain PF00046.29 ORY52046.1 - 2.3e-16 59.4 0.7 4.1e-16 58.6 0.7 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY52046.1 - 9.1e-05 22.3 0.5 0.00026 20.8 0.1 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 ORY52047.1 - 3.9e-16 58.6 0.4 7e-16 57.8 0.4 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY52047.1 - 1.9e-05 24.5 0.1 6.2e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 ORY52048.1 - 2.5e-13 49.6 0.5 2.5e-13 49.6 0.5 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 ORY52048.1 - 0.0038 17.1 0.1 0.0093 15.8 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain CTF_NFI PF00859.18 ORY52049.1 - 0.041 13.8 5.0 0.063 13.2 5.0 1.2 1 0 0 1 1 1 0 CTF/NF-I family transcription modulation region FoP_duplication PF13865.6 ORY52050.1 - 1.2e-06 29.0 7.5 1.2e-06 29.0 7.5 3.2 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.22 ORY52050.1 - 0.00014 21.6 0.0 0.00026 20.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mannosyl_trans3 PF11051.8 ORY52051.1 - 1.6e-09 37.5 0.0 2.8e-09 36.7 0.0 1.4 2 0 0 2 2 2 1 Mannosyltransferase putative DUF3963 PF13124.6 ORY52053.1 - 0.16 12.0 0.6 0.73 9.9 0.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3963) OrfB_Zn_ribbon PF07282.11 ORY52054.1 - 0.0057 16.6 0.1 0.0057 16.6 0.1 2.4 2 0 0 2 2 2 1 Putative transposase DNA-binding domain MFS_1 PF07690.16 ORY52055.1 - 2.9e-09 36.3 20.6 8.2e-09 34.8 20.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 ORY52055.1 - 0.00052 19.0 8.7 0.00065 18.7 8.7 1.1 1 0 0 1 1 1 1 MFS_1 like family ubiquitin PF00240.23 ORY52056.1 - 0.00024 20.8 0.0 0.037 13.8 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin family LapA_dom PF06305.11 ORY52056.1 - 9.2 6.2 7.0 0.88 9.4 0.1 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain MFS_1 PF07690.16 ORY52057.1 - 8.9e-15 54.5 36.3 3.8e-14 52.4 32.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PP2C PF00481.21 ORY52058.1 - 9.7e-30 104.0 0.0 1.5e-29 103.4 0.0 1.2 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 ORY52058.1 - 0.00044 19.9 0.0 0.00049 19.8 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Cuticle_1 PF08140.11 ORY52058.1 - 0.18 11.9 0.1 0.34 11.0 0.1 1.5 1 0 0 1 1 1 0 Crustacean cuticle protein repeat Glyco_hydro_17 PF00332.18 ORY52058.1 - 0.2 11.2 0.0 0.27 10.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 MA3 PF02847.17 ORY52059.1 - 4.6e-29 100.7 0.1 9.9e-29 99.6 0.1 1.6 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 ORY52059.1 - 5.4e-13 49.1 0.4 1.8e-12 47.4 0.1 2.0 2 0 0 2 2 2 1 MIF4G domain CENP-B_dimeris PF09026.10 ORY52059.1 - 0.0065 16.8 10.7 0.0065 16.8 10.7 3.8 3 1 0 3 3 3 1 Centromere protein B dimerisation domain Peptidase_M28 PF04389.17 ORY52060.1 - 5.4e-42 143.7 0.0 1.8e-41 142.0 0.0 1.9 2 1 0 2 2 2 1 Peptidase family M28 Nicastrin PF05450.15 ORY52060.1 - 0.00018 21.0 0.0 0.00021 20.8 0.0 1.3 1 0 0 1 1 1 1 Nicastrin DUF572 PF04502.13 ORY52061.1 - 2.1e-68 231.4 1.5 2.5e-68 231.2 1.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Esterase_phd PF10503.9 ORY52061.1 - 0.017 14.6 0.1 0.025 14.1 0.1 1.1 1 0 0 1 1 1 0 Esterase PHB depolymerase UPF0203 PF05254.12 ORY52062.1 - 4.3e-23 81.3 3.3 4.8e-23 81.2 3.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Pet191_N PF10203.9 ORY52062.1 - 0.00065 20.0 1.0 0.21 11.9 0.2 2.1 2 0 0 2 2 2 2 Cytochrome c oxidase assembly protein PET191 UCR_hinge PF02320.16 ORY52062.1 - 0.0022 18.2 1.3 0.43 10.8 0.4 2.1 2 0 0 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein COX6B PF02297.17 ORY52062.1 - 0.0042 17.3 2.3 0.0049 17.1 2.3 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Cmc1 PF08583.10 ORY52062.1 - 0.0085 16.1 2.3 1.2 9.2 0.0 2.2 2 1 0 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 ORY52062.1 - 0.0086 16.4 0.2 0.52 10.7 0.1 2.2 2 0 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) CX9C PF16860.5 ORY52062.1 - 0.056 13.5 1.7 0.084 12.9 0.3 1.9 2 0 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF5339 PF17274.2 ORY52062.1 - 0.065 14.1 3.6 0.61 11.0 2.3 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5339) NPR1_interact PF15699.5 ORY52063.1 - 0.14 12.8 2.7 0.27 11.9 2.7 1.3 1 0 0 1 1 1 0 NPR1 interacting WD40 PF00400.32 ORY52063.1 - 0.15 13.0 12.5 6.1 7.9 0.7 5.5 6 0 0 6 6 6 0 WD domain, G-beta repeat F-box-like PF12937.7 ORY52064.1 - 0.021 14.7 0.7 0.066 13.1 0.0 2.1 2 0 0 2 2 2 0 F-box-like DUF2475 PF10629.9 ORY52065.1 - 5.3e-33 113.1 6.6 2.4e-07 30.8 0.0 5.3 5 0 0 5 5 5 5 Protein of unknown function (DUF2475) GCP_C_terminal PF04130.13 ORY52066.1 - 1.6e-30 106.7 0.0 3.1e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 ORY52066.1 - 1.1e-16 61.4 0.0 3.4e-16 59.8 0.0 1.9 1 1 0 1 1 1 1 Gamma tubulin complex component N-terminal PPR_2 PF13041.6 ORY52067.1 - 2.2e-44 149.4 0.0 8.3e-11 41.9 0.1 10.1 7 2 4 11 11 11 8 PPR repeat family PPR_3 PF13812.6 ORY52067.1 - 4.1e-28 97.2 3.7 1.7e-07 31.2 0.1 9.4 8 2 2 10 10 10 4 Pentatricopeptide repeat domain PPR PF01535.20 ORY52067.1 - 4.3e-26 89.3 23.0 3.9e-05 23.6 0.0 13.4 16 0 0 16 16 15 4 PPR repeat PPR_long PF17177.4 ORY52067.1 - 8.5e-25 87.4 3.2 4.3e-11 42.6 0.0 5.2 3 1 2 5 5 5 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 ORY52067.1 - 6.9e-22 76.9 1.4 0.00092 18.9 0.0 9.1 10 0 0 10 10 10 5 PPR repeat TPR_19 PF14559.6 ORY52067.1 - 1.2e-05 25.8 0.0 9.5 6.8 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat ATP13 PF12921.7 ORY52067.1 - 5.9e-05 22.9 0.0 0.0088 15.9 0.0 3.9 4 0 0 4 4 4 1 Mitochondrial ATPase expression TPR_8 PF13181.6 ORY52067.1 - 0.00038 20.4 0.7 0.85 10.0 0.2 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY52067.1 - 0.00046 20.8 3.1 25 6.0 0.0 7.3 9 0 0 9 9 8 0 Tetratricopeptide repeat MRP-S27 PF10037.9 ORY52067.1 - 0.0096 14.8 0.2 0.11 11.4 0.1 2.6 1 1 1 2 2 2 1 Mitochondrial 28S ribosomal protein S27 TPR_15 PF13429.6 ORY52067.1 - 0.063 12.5 0.0 1.3 8.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Clathrin PF00637.20 ORY52067.1 - 0.07 13.0 0.6 24 4.8 0.1 3.9 2 1 1 3 3 3 0 Region in Clathrin and VPS RPN7 PF10602.9 ORY52067.1 - 0.082 12.6 0.0 3.1 7.5 0.0 3.4 4 0 0 4 4 4 0 26S proteasome subunit RPN7 Siah-Interact_N PF09032.11 ORY52067.1 - 0.15 12.4 0.8 2.8 8.3 0.0 2.7 2 0 0 2 2 2 0 Siah interacting protein, N terminal RPM2 PF08579.11 ORY52067.1 - 0.25 11.7 0.7 51 4.3 0.2 4.4 4 1 2 6 6 6 0 Mitochondrial ribonuclease P subunit (RPM2) TPR_7 PF13176.6 ORY52067.1 - 0.29 11.3 1.3 54 4.2 0.0 4.2 6 0 0 6 6 3 0 Tetratricopeptide repeat Radical_SAM PF04055.21 ORY52068.1 - 1.3e-19 71.2 0.0 2.1e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily UPF0004 PF00919.20 ORY52068.1 - 2.8e-16 59.4 0.0 8.4e-16 57.8 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 ORY52068.1 - 7.5e-06 25.9 1.3 1.9e-05 24.6 0.2 2.3 2 0 0 2 2 2 1 TRAM domain Ribosomal_L34 PF00468.17 ORY52069.1 - 7.1e-18 64.3 5.3 1e-17 63.8 5.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L34 tRNA_U5-meth_tr PF05958.11 ORY52070.1 - 3.5e-12 46.0 0.0 7.9e-12 44.8 0.0 1.6 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 ORY52070.1 - 1.3e-10 41.2 0.1 2.1e-09 37.4 0.1 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY52070.1 - 1.7e-07 31.8 0.1 8e-07 29.7 0.1 2.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 ORY52070.1 - 1.6e-05 24.6 0.0 3.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_4 PF02390.17 ORY52070.1 - 1.7e-05 24.4 0.2 2.9e-05 23.6 0.2 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 ORY52070.1 - 2.7e-05 23.8 0.1 7.2e-05 22.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 ORY52070.1 - 4.4e-05 23.1 0.2 0.00013 21.6 0.1 1.8 1 1 1 2 2 2 1 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.18 ORY52070.1 - 0.00074 18.9 0.2 0.0014 18.0 0.2 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 ORY52070.1 - 0.0048 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY52070.1 - 0.0089 16.7 0.1 0.028 15.0 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 ORY52070.1 - 0.076 12.8 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AviRa PF11599.8 ORY52070.1 - 0.1 12.1 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 RRNA methyltransferase AviRa DNA_pol_B_palm PF14792.6 ORY52070.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase beta palm VIT1 PF01988.19 ORY52071.1 - 3.5e-70 236.2 0.4 4e-70 236.0 0.4 1.0 1 0 0 1 1 1 1 VIT family VIT1 PF01988.19 ORY52072.1 - 2.3e-68 230.3 1.3 2.7e-68 230.1 1.3 1.1 1 0 0 1 1 1 1 VIT family OrfB_Zn_ribbon PF07282.11 ORY52073.1 - 0.0057 16.5 0.1 0.0057 16.5 0.1 2.5 2 0 0 2 2 2 1 Putative transposase DNA-binding domain VIT1 PF01988.19 ORY52074.1 - 1.8e-68 230.7 0.5 2.1e-68 230.4 0.5 1.1 1 0 0 1 1 1 1 VIT family DUF443 PF04276.12 ORY52074.1 - 0.051 13.4 0.1 0.079 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF443) ATP-synt_C PF00137.21 ORY52075.1 - 3.1e-10 40.2 6.0 4e-10 39.9 6.0 1.2 1 0 0 1 1 1 1 ATP synthase subunit C YaiA PF16362.5 ORY52076.1 - 0.026 14.6 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 YaiA protein MF_alpha_N PF05436.11 ORY52076.1 - 0.18 11.7 0.1 0.29 11.1 0.1 1.2 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Ist1 PF03398.14 ORY52077.1 - 1.6e-59 200.5 5.8 2e-59 200.2 5.8 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Ada3 PF10198.9 ORY52077.1 - 0.052 13.7 0.7 0.084 13.0 0.7 1.3 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 zf-C2H2_aberr PF17017.5 ORY52078.1 - 0.00086 19.5 0.6 0.00086 19.5 0.6 2.9 2 1 1 3 3 3 1 Aberrant zinc-finger zf-C2H2 PF00096.26 ORY52078.1 - 0.001 19.4 10.6 0.31 11.6 4.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY52078.1 - 0.041 14.7 17.7 0.26 12.3 3.4 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY52078.1 - 0.095 13.2 4.9 0.58 10.7 0.7 2.9 2 0 0 2 2 2 0 Zinc-finger double domain zf-BED PF02892.15 ORY52078.1 - 0.71 9.9 6.7 6.8 6.8 1.4 2.7 2 0 0 2 2 2 0 BED zinc finger zf-C2HE PF16278.5 ORY52078.1 - 0.8 10.2 8.5 0.24 11.9 1.2 2.9 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_jaz PF12171.8 ORY52078.1 - 5.8 7.3 6.8 0.5 10.7 0.3 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding LRR_4 PF12799.7 ORY52079.1 - 1.8e-08 34.5 11.7 0.3 11.6 0.5 7.2 4 2 2 8 8 8 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 ORY52079.1 - 5.4e-07 29.2 19.8 1 9.6 0.1 9.8 10 0 0 10 10 10 4 Leucine Rich repeat UBX PF00789.20 ORY52079.1 - 0.00017 21.7 0.1 0.00066 19.8 0.0 2.0 2 0 0 2 2 2 1 UBX domain LRR_1 PF00560.33 ORY52079.1 - 0.48 11.2 10.1 18 6.4 0.7 5.7 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.6 ORY52079.1 - 1.8 8.4 12.0 6.7 6.6 0.8 4.6 4 1 1 5 5 5 0 Leucine rich repeat Cwf_Cwc_15 PF04889.12 ORY52079.1 - 2.5 7.8 11.1 6 6.5 11.1 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein HTH_50 PF18024.1 ORY52081.1 - 1.2 8.8 5.4 70 3.1 0.1 4.4 6 0 0 6 6 6 0 Helix-turn-helix domain Prefoldin_2 PF01920.20 ORY52082.1 - 1.4e-13 50.7 6.4 1.8e-13 50.4 6.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit Lectin_N PF03954.14 ORY52082.1 - 0.28 10.9 2.5 1.1 9.0 0.1 2.0 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain Swi5 PF07061.11 ORY52082.1 - 0.39 10.8 4.8 1.7 8.8 0.8 2.2 2 0 0 2 2 2 0 Swi5 V-ATPase_C PF03223.15 ORY52082.1 - 0.44 9.9 5.2 0.78 9.1 1.0 2.0 1 1 1 2 2 2 0 V-ATPase subunit C ABC_tran_CTD PF16326.5 ORY52082.1 - 2.4 8.5 7.2 13 6.2 1.0 2.7 2 1 0 2 2 2 0 ABC transporter C-terminal domain Seryl_tRNA_N PF02403.22 ORY52082.1 - 5.6 7.2 9.8 4.4 7.6 3.9 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6_N PF17675.1 ORY52082.1 - 8.3 6.9 9.8 60 4.2 9.8 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region LETM1 PF07766.13 ORY52083.1 - 8.4e-22 77.8 0.1 2.4e-21 76.3 0.1 1.6 1 1 0 1 1 1 1 LETM1-like protein EF-hand_7 PF13499.6 ORY52084.1 - 4.4e-09 36.6 1.0 6.4e-09 36.1 1.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 ORY52084.1 - 4.6e-09 35.2 0.1 0.0017 17.7 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 ORY52084.1 - 1.2e-08 34.1 1.2 0.00015 21.4 0.5 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 ORY52084.1 - 4.7e-05 22.7 0.0 0.016 14.7 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 ORY52084.1 - 0.0055 16.5 1.1 0.76 9.7 0.0 2.7 1 1 1 2 2 2 1 EF-hand domain pair SPARC_Ca_bdg PF10591.9 ORY52084.1 - 0.0087 16.4 0.3 0.052 13.9 0.3 1.9 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 ORY52084.1 - 0.027 14.4 0.7 0.2 11.6 0.8 2.1 1 1 0 1 1 1 0 Caleosin related protein Flavokinase PF01687.17 ORY52084.1 - 0.085 13.2 0.2 0.11 12.9 0.2 1.2 1 0 0 1 1 1 0 Riboflavin kinase Swi5 PF07061.11 ORY52085.1 - 4.9e-17 61.8 1.4 5.8e-17 61.6 1.4 1.1 1 0 0 1 1 1 1 Swi5 His_Phos_1 PF00300.22 ORY52085.1 - 0.023 14.4 0.1 0.026 14.2 0.1 1.0 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) PEP-utilisers_N PF05524.13 ORY52085.1 - 0.074 13.2 2.1 0.092 12.9 2.1 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal PKcGMP_CC PF16808.5 ORY52085.1 - 0.076 12.9 0.4 0.14 12.1 0.4 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Hira PF07569.11 ORY52086.1 - 2.2e-36 125.7 0.1 1.1e-25 90.6 0.1 2.3 2 0 0 2 2 2 2 TUP1-like enhancer of split WD40 PF00400.32 ORY52086.1 - 9.9e-30 102.2 17.5 4.8e-07 30.4 0.3 8.1 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY52086.1 - 8.3e-15 54.9 0.1 0.047 14.0 0.0 6.2 3 1 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 ORY52086.1 - 9.7e-07 28.5 4.1 1.7e-06 27.7 0.7 2.4 2 0 0 2 2 2 1 HIRA B motif tRNA_synthFbeta PF17759.1 ORY52087.1 - 9.4e-50 169.0 0.0 1.4e-49 168.5 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 ORY52087.1 - 6.4e-32 109.6 0.4 1.1e-30 105.7 0.2 2.5 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 ORY52087.1 - 6.1e-28 97.6 0.1 1.1e-27 96.8 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 ORY52087.1 - 6.5e-21 74.4 0.0 2.6e-18 66.1 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain Pyr_redox_2 PF07992.14 ORY52088.1 - 6.4e-47 160.2 0.7 7.3e-47 160.0 0.7 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY52088.1 - 1.6e-17 63.8 0.1 6.2e-14 52.3 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 ORY52088.1 - 4.9e-14 52.3 0.7 9.8e-11 41.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 ORY52088.1 - 2.6e-05 23.6 0.8 0.00016 21.0 0.1 2.4 2 1 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 ORY52088.1 - 0.00066 20.1 0.3 0.088 13.3 0.0 3.0 3 0 0 3 3 3 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 ORY52088.1 - 0.00094 19.4 0.6 0.019 15.2 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 ORY52088.1 - 0.0017 17.5 9.3 0.028 13.5 1.1 4.0 3 2 1 5 5 5 1 Glucose inhibited division protein A DAO PF01266.24 ORY52088.1 - 0.0017 18.0 0.0 0.0043 16.7 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 ORY52088.1 - 0.0034 16.3 0.1 0.06 12.2 0.1 2.2 2 0 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.7 ORY52088.1 - 0.0041 16.5 1.0 0.015 14.7 0.3 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 ORY52088.1 - 0.0053 15.5 1.1 0.1 11.3 0.4 2.4 1 1 0 2 2 2 1 HI0933-like protein K_oxygenase PF13434.6 ORY52088.1 - 0.0062 15.7 0.1 0.049 12.8 0.0 2.3 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 ORY52088.1 - 0.008 15.5 0.0 0.036 13.3 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 ORY52088.1 - 0.039 13.0 3.5 0.059 12.5 1.8 2.1 2 0 0 2 2 2 0 FAD binding domain CdvA PF18822.1 ORY52088.1 - 0.045 13.6 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 CdvA-like coiled-coil domain Shikimate_DH PF01488.20 ORY52088.1 - 0.13 12.4 0.0 26 4.9 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Peroxin-13_N PF04088.13 ORY52089.1 - 1.4e-39 135.7 0.1 1.8e-39 135.3 0.1 1.1 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.28 ORY52089.1 - 1e-13 50.7 0.0 4.6e-13 48.5 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 ORY52089.1 - 2e-11 43.4 0.1 5.9e-11 41.9 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 ORY52089.1 - 1.2e-09 37.8 0.0 6.2e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain OAD_gamma PF04277.13 ORY52089.1 - 0.00082 19.9 0.1 0.0035 17.9 0.0 2.0 2 0 0 2 2 2 1 Oxaloacetate decarboxylase, gamma chain Nucleoporin_FG2 PF15967.5 ORY52089.1 - 4.6 5.7 10.1 6.6 5.1 10.1 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeated region FAM72 PF14976.6 ORY52090.1 - 9.3e-49 165.3 3.8 1.4e-48 164.7 3.8 1.2 1 0 0 1 1 1 1 FAM72 protein UBA PF00627.31 ORY52091.1 - 1.1e-10 41.2 0.1 2.4e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain UBA_3 PF09288.10 ORY52091.1 - 0.0014 18.3 0.1 0.0027 17.5 0.1 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Rhomboid PF01694.22 ORY52091.1 - 0.0046 17.0 3.0 0.0046 17.0 3.0 1.8 1 1 1 2 2 2 1 Rhomboid family CUE PF02845.16 ORY52091.1 - 0.033 13.9 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 CUE domain HTH_8 PF02954.19 ORY52091.1 - 0.083 12.7 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family Atthog PF18800.1 ORY52091.1 - 0.086 12.7 0.2 0.086 12.7 0.2 1.6 2 0 0 2 2 2 0 Attenuator of Hedgehog ApoO PF09769.9 ORY52091.1 - 1.5 8.8 6.9 1.6 8.7 0.1 3.1 3 1 0 3 3 3 0 Apolipoprotein O Sec1 PF00995.23 ORY52092.1 - 1e-112 378.3 0.0 4.6e-110 369.5 0.0 2.2 2 0 0 2 2 2 2 Sec1 family CEP44 PF15007.6 ORY52092.1 - 8.7e-40 135.8 0.0 1.9e-39 134.7 0.0 1.6 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 DUF1664 PF07889.12 ORY52092.1 - 0.0011 19.0 1.4 0.0026 17.8 1.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) TPR_MLP1_2 PF07926.12 ORY52092.1 - 0.0074 16.4 0.2 0.03 14.4 0.2 2.0 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein GAS PF13851.6 ORY52092.1 - 0.011 15.1 0.4 0.023 14.0 0.4 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 ORY52092.1 - 0.055 12.3 2.1 0.1 11.4 2.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein EzrA PF06160.12 ORY52092.1 - 0.13 10.4 0.9 0.25 9.5 0.9 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Tmemb_18A PF09771.9 ORY52092.1 - 0.15 12.5 0.4 0.36 11.2 0.4 1.6 1 0 0 1 1 1 0 Transmembrane protein 188 Spectrin PF00435.21 ORY52092.1 - 0.2 12.2 2.3 0.75 10.3 2.3 2.1 1 0 0 1 1 1 0 Spectrin repeat FTA4 PF13093.6 ORY52092.1 - 0.43 10.4 6.5 0.93 9.3 6.5 1.5 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Fib_alpha PF08702.10 ORY52092.1 - 1.6 8.9 4.3 7 6.8 2.7 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Nucleoporin_FG2 PF15967.5 ORY52093.1 - 6.2e-22 77.9 2.2 6.2e-22 77.9 2.2 3.1 2 1 1 3 3 3 1 Nucleoporin FG repeated region Nucleoporin_FG PF13634.6 ORY52093.1 - 6.3e-08 33.4 61.4 0.0065 17.3 20.1 3.8 2 1 1 3 3 3 3 Nucleoporin FG repeat region P4Ha_N PF08336.11 ORY52093.1 - 0.00064 19.8 1.1 0.16 12.0 0.1 2.3 1 1 1 2 2 2 2 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region PriC PF07445.12 ORY52093.1 - 0.0022 17.9 0.8 0.0031 17.5 0.8 1.2 1 0 0 1 1 1 1 Primosomal replication protein priC Syntaxin-6_N PF09177.11 ORY52093.1 - 0.016 15.8 0.6 0.055 14.0 0.6 1.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal HSBP1 PF06825.12 ORY52093.1 - 0.14 12.1 0.1 0.37 10.7 0.0 1.7 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Sec20 PF03908.13 ORY52093.1 - 0.3 11.0 1.1 1.3 9.0 0.2 2.0 2 0 0 2 2 2 0 Sec20 FliJ PF02050.16 ORY52093.1 - 2 8.7 4.7 19 5.5 0.7 2.4 1 1 1 2 2 2 0 Flagellar FliJ protein HEAT PF02985.22 ORY52094.1 - 9e-08 31.7 3.1 0.065 13.5 0.0 7.0 7 0 0 7 7 7 2 HEAT repeat Vac14_Fab1_bd PF12755.7 ORY52094.1 - 1.8e-05 25.2 4.4 0.043 14.4 0.6 4.0 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 ORY52094.1 - 0.064 11.8 4.9 0.36 9.3 0.2 2.8 3 0 0 3 3 3 0 Adaptin N terminal region RTP1_C1 PF10363.9 ORY52094.1 - 0.19 11.9 0.1 0.19 11.9 0.1 3.1 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Macoilin PF09726.9 ORY52094.1 - 9.9 4.6 7.1 21 3.5 7.1 1.5 1 0 0 1 1 1 0 Macoilin family WD40 PF00400.32 ORY52095.1 - 3.2e-26 91.1 10.5 6.4e-07 30.0 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY52095.1 - 1.2e-06 28.8 0.0 0.0015 18.7 0.0 3.8 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY52095.1 - 0.0017 17.1 0.1 2.3 6.8 0.0 3.8 2 2 3 5 5 5 3 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY52095.1 - 0.21 10.9 0.0 3.3 7.0 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain zf-AN1 PF01428.16 ORY52096.1 - 0.0098 16.0 2.4 0.017 15.3 2.4 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Peptidase_M24 PF00557.24 ORY52097.1 - 1.8e-19 70.3 0.0 2.7e-19 69.7 0.0 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 CFAP91 PF14738.6 ORY52098.1 - 9.6e-57 191.3 14.2 9.6e-57 191.3 14.2 3.3 4 0 0 4 4 4 1 Cilia- and flagella-associated protein 91 DUF5624 PF18538.1 ORY52098.1 - 0.13 12.4 2.7 0.1 12.7 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) FBPase PF00316.20 ORY52099.1 - 9.8e-69 230.6 0.3 1.3e-68 230.2 0.3 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 ORY52099.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Inositol monophosphatase family efThoc1 PF11957.8 ORY52100.1 - 2.1e-94 317.0 6.0 2.7e-94 316.6 6.0 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Bcl-2 PF00452.19 ORY52100.1 - 0.16 12.7 0.7 3.7 8.3 0.0 3.1 2 1 1 3 3 3 0 Apoptosis regulator proteins, Bcl-2 family Ribosomal_S25 PF03297.15 ORY52101.1 - 7e-43 144.9 2.9 7e-43 144.9 2.9 2.0 1 1 1 2 2 2 1 S25 ribosomal protein MarR_2 PF12802.7 ORY52101.1 - 0.029 14.3 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 MarR family WD40 PF00400.32 ORY52102.1 - 1.8e-23 82.4 8.8 6.9e-06 26.7 0.0 6.0 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY52102.1 - 2.9e-13 49.9 0.0 0.062 13.6 0.0 5.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY52102.1 - 0.00014 21.8 0.0 5.2 6.9 0.0 3.4 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ORY52102.1 - 0.00025 20.1 0.6 0.16 10.9 0.0 3.4 2 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4596 PF15363.6 ORY52102.1 - 1.8 8.9 7.6 10 6.4 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4596) CDH-cyt PF16010.5 ORY52103.1 - 1.5e-21 76.9 12.5 1e-11 44.9 0.5 2.5 2 0 0 2 2 2 2 Cytochrome domain of cellobiose dehydrogenase IQ PF00612.27 ORY52104.1 - 3.6e-08 32.5 7.4 2.8e-05 23.5 0.4 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif MCM PF00493.23 ORY52105.1 - 1.5e-96 321.8 0.2 2e-96 321.4 0.2 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 ORY52105.1 - 2.9e-34 117.6 0.0 5.3e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 ORY52105.1 - 4.9e-22 78.2 0.4 1.3e-21 76.8 0.3 1.8 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 ORY52105.1 - 4.3e-12 46.5 0.0 1.2e-11 45.1 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 ORY52105.1 - 3.2e-08 33.2 0.1 6.4e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 ORY52105.1 - 0.0063 16.2 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 ORY52105.1 - 0.0074 16.1 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF702 PF05142.12 ORY52106.1 - 0.41 11.1 5.2 0.23 11.9 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Ribosomal_L24e PF01246.20 ORY52107.1 - 6.7e-11 42.3 1.9 1.2e-10 41.4 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L24e PAS_10 PF13596.6 ORY52107.1 - 0.22 12.1 0.4 0.32 11.6 0.4 1.3 1 0 0 1 1 1 0 PAS domain Spem1 PF15670.5 ORY52107.1 - 0.25 10.9 4.0 0.27 10.8 4.0 1.0 1 0 0 1 1 1 0 Spermatid maturation protein 1 FANC_SAP PF18081.1 ORY52107.1 - 0.39 10.9 4.9 0.23 11.7 1.9 2.1 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain ubiquitin PF00240.23 ORY52108.1 - 2.9e-05 23.7 0.0 0.00061 19.5 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin family LapA_dom PF06305.11 ORY52108.1 - 0.88 9.4 0.0 0.88 9.4 0.0 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain RIBIOP_C PF04950.12 ORY52109.1 - 2.5e-115 384.9 0.0 2.5e-115 384.9 0.0 2.0 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 ORY52109.1 - 8e-19 67.5 0.0 5.7e-18 64.8 0.0 2.4 2 0 0 2 2 2 1 AARP2CN (NUC121) domain Zip PF02535.22 ORY52109.1 - 1.5 8.0 2.5 10 5.2 1.6 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter ResIII PF04851.15 ORY52110.1 - 6.9e-21 75.0 0.0 2.5e-20 73.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 ORY52110.1 - 1.9e-18 66.8 0.1 7.4e-18 64.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY52110.1 - 9.4e-16 58.1 0.0 2.3e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC4 PF02732.15 ORY52110.1 - 6e-13 49.3 1.1 1.4e-11 44.8 0.1 2.7 2 1 0 2 2 2 1 ERCC4 domain FANCM-MHF_bd PF16783.5 ORY52110.1 - 1.8e-05 24.8 0.1 4.8e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 FANCM to MHF binding domain SWI2_SNF2 PF18766.1 ORY52110.1 - 0.0018 18.0 0.5 0.0071 16.0 0.0 2.2 3 0 0 3 3 3 1 SWI2/SNF2 ATPase Pyrid_oxidase_2 PF13883.6 ORY52110.1 - 2.4 8.1 4.5 5.9 6.8 4.5 1.6 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Ribosomal_L24e PF01246.20 ORY52111.1 - 3.4e-27 94.5 0.2 3.4e-27 94.5 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e FANC_SAP PF18081.1 ORY52111.1 - 0.34 11.1 3.7 0.39 10.9 1.6 2.2 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain DUF1700 PF08006.11 ORY52112.1 - 0.0081 15.7 0.2 0.017 14.7 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1700) M-factor PF03855.13 ORY52112.1 - 0.18 12.0 5.8 0.49 10.6 5.8 1.7 1 0 0 1 1 1 0 M-factor DMRL_synthase PF00885.19 ORY52115.1 - 9.4e-53 177.8 0.0 1.1e-52 177.6 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase zf-DNL PF05180.12 ORY52116.1 - 5.8e-26 90.2 0.8 1e-25 89.4 0.8 1.4 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.13 ORY52116.1 - 0.022 14.8 0.2 0.022 14.8 0.2 1.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-ZPR1 PF03367.13 ORY52116.1 - 0.22 11.3 1.5 0.51 10.2 0.5 2.0 1 1 1 2 2 2 0 ZPR1 zinc-finger domain zinc_ribbon_4 PF13717.6 ORY52116.1 - 0.81 9.7 0.0 0.81 9.7 0.0 3.0 3 0 0 3 3 3 0 zinc-ribbon domain COX6B PF02297.17 ORY52117.1 - 3.4e-20 72.1 7.3 3.8e-20 71.9 7.3 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.14 ORY52117.1 - 0.011 15.7 0.5 0.015 15.3 0.5 1.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain CX9C PF16860.5 ORY52117.1 - 0.16 12.0 3.6 0.25 11.4 3.6 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Med10 PF09748.9 ORY52118.1 - 1.3e-23 83.2 0.3 1.5e-23 83.1 0.3 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF4125 PF13526.6 ORY52118.1 - 0.00052 19.7 0.1 0.0008 19.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4125) ZapB PF06005.12 ORY52118.1 - 0.85 10.1 6.0 5.2 7.6 0.5 2.9 1 1 1 2 2 2 0 Cell division protein ZapB API5 PF05918.11 ORY52120.1 - 1.7 7.4 2.6 1.9 7.2 2.6 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Peptidase_S9 PF00326.21 ORY52121.1 - 2e-07 30.7 0.0 4.3e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 ORY52121.1 - 5.1e-07 29.6 0.1 9.4e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 Putative esterase Tannase PF07519.11 ORY52121.1 - 0.031 13.2 0.0 0.047 12.6 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase Abhydrolase_1 PF00561.20 ORY52121.1 - 0.072 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PolyA_pol PF01743.20 ORY52122.1 - 2.3e-28 99.2 0.1 4.1e-28 98.3 0.1 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 ORY52122.1 - 3.4e-05 23.5 0.0 0.00014 21.6 0.0 2.1 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Metallophos PF00149.28 ORY52123.1 - 7.3e-17 62.6 2.1 9.2e-17 62.2 2.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RhoGAP PF00620.27 ORY52124.1 - 1.2e-12 47.9 0.0 2.2e-07 30.8 0.0 2.5 2 0 0 2 2 2 2 RhoGAP domain Exo_endo_phos PF03372.23 ORY52124.1 - 1.8e-10 40.8 0.0 4e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Dioxygenase_N PF04444.14 ORY52124.1 - 0.15 11.9 0.0 11 5.9 0.0 3.0 3 0 0 3 3 3 0 Catechol dioxygenase N terminus PapD-like PF14874.6 ORY52124.1 - 0.15 12.2 0.1 0.41 10.8 0.0 1.7 2 0 0 2 2 2 0 Flagellar-associated PapD-like PRP3 PF08572.10 ORY52125.1 - 4.5e-66 222.8 0.4 4.5e-66 222.8 0.4 3.1 2 1 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 ORY52125.1 - 1.3e-41 142.1 0.2 1.7e-40 138.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) DUF5421 PF17458.2 ORY52125.1 - 8.7 5.6 10.2 0.34 10.3 3.9 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5421) DUF3309 PF11752.8 ORY52268.1 - 0.05 13.6 13.6 14 5.9 0.4 4.5 1 1 3 4 4 4 0 Protein of unknown function (DUF3309) OTOS PF15182.6 ORY52268.1 - 0.51 10.3 13.3 5.5e+03 -2.6 13.3 4.0 1 1 0 1 1 1 0 Otospiralin OrsD PF12013.8 ORY52270.1 - 0.006 17.0 5.5 0.084 13.3 2.7 2.7 1 1 1 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-H2C2_5 PF13909.6 ORY52270.1 - 0.062 13.1 9.6 1.4 8.7 3.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Actin_micro PF17003.5 ORY52270.1 - 1.4 8.1 3.5 6 5.9 3.5 2.0 1 1 0 1 1 1 0 Putative actin-like family zf-C2H2_4 PF13894.6 ORY52270.1 - 3.1 8.9 10.2 7.1 7.8 0.2 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY52270.1 - 6.9 7.3 10.6 14 6.4 0.3 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type WD40 PF00400.32 ORY52272.1 - 2.1e-110 357.5 53.2 9e-11 42.2 0.1 12.5 12 0 0 12 12 12 12 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY52272.1 - 6.5e-37 125.7 12.6 0.002 18.4 0.0 11.4 1 1 11 12 12 12 9 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY52272.1 - 5.7e-18 64.9 31.7 0.013 14.1 0.0 11.9 2 2 9 12 12 12 10 Nucleoporin Nup120/160 eIF2A PF08662.11 ORY52272.1 - 1.1e-15 58.1 4.9 0.0021 17.9 0.0 5.8 1 1 5 6 6 6 6 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 ORY52272.1 - 2.4e-13 49.7 24.1 0.48 9.3 0.0 10.9 1 1 9 10 10 10 6 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 ORY52272.1 - 7.7e-12 45.1 6.3 0.0072 15.7 0.0 6.2 2 2 5 7 7 7 4 WD40-like domain NACHT PF05729.12 ORY52272.1 - 7.7e-07 29.2 0.0 1.7e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PALB2_WD40 PF16756.5 ORY52272.1 - 8.2e-06 25.0 19.3 1.8 7.4 0.1 8.9 3 3 6 9 9 9 2 Partner and localizer of BRCA2 WD40 domain Cytochrom_D1 PF02239.16 ORY52272.1 - 6.5e-05 21.6 5.6 0.14 10.7 0.1 3.5 2 1 1 3 3 3 3 Cytochrome D1 heme domain Frtz PF11768.8 ORY52272.1 - 0.0012 17.3 0.1 1.4 7.1 0.0 4.8 3 3 3 7 7 7 2 WD repeat-containing and planar cell polarity effector protein Fritz PQQ PF01011.21 ORY52272.1 - 0.0083 16.0 11.5 18 5.5 0.0 7.7 8 0 0 8 8 8 0 PQQ enzyme repeat FixS PF03597.15 ORY52272.1 - 0.085 12.6 0.3 6.1 6.6 0.0 3.6 3 0 0 3 3 3 0 Cytochrome oxidase maturation protein cbb3-type AAA_16 PF13191.6 ORY52272.1 - 0.1 13.0 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain PRCC PF10253.9 ORY52275.1 - 1.9e-15 58.2 3.8 2.6e-15 57.8 3.8 1.1 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting TrmO PF01980.16 ORY52276.1 - 4.3e-30 104.4 0.0 4.6e-29 101.1 0.0 2.4 1 1 0 1 1 1 1 tRNA-methyltransferase O LRR_6 PF13516.6 ORY52278.1 - 4e-07 29.6 0.5 6.9e-06 25.7 0.3 2.4 2 0 0 2 2 2 1 Leucine Rich repeat Acetyltransf_3 PF13302.7 ORY52279.1 - 0.0039 17.9 0.0 0.0062 17.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Skp1 PF01466.19 ORY52280.1 - 7.8e-29 99.5 1.4 7.8e-29 99.5 1.4 1.9 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 ORY52280.1 - 4.9e-20 71.5 1.1 1.2e-19 70.3 0.1 2.1 2 1 1 3 3 3 1 Skp1 family, tetramerisation domain Atg14 PF10186.9 ORY52281.1 - 3.2e-05 23.2 43.1 0.0069 15.5 12.2 4.1 2 2 2 4 4 4 3 Vacuolar sorting 38 and autophagy-related subunit 14 PI_PP_C PF18365.1 ORY52281.1 - 0.025 14.6 4.8 1.4 8.9 0.9 3.2 3 1 0 3 3 3 0 Phosphoinositide phosphatase C-terminal domain IRF PF00605.17 ORY52281.1 - 0.04 14.2 1.9 7.7 6.9 0.0 3.4 4 0 0 4 4 4 0 Interferon regulatory factor transcription factor AP3B1_C PF14796.6 ORY52281.1 - 0.064 13.5 1.8 0.22 11.8 1.8 1.9 1 0 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Mur_ligase_C PF02875.21 ORY52281.1 - 1.2 9.5 4.1 32 4.9 0.3 4.1 2 2 1 3 3 3 0 Mur ligase family, glutamate ligase domain UNC45-central PF11701.8 ORY52281.1 - 2.2 8.2 26.4 8.4 6.3 0.5 7.7 4 2 4 8 8 8 0 Myosin-binding striated muscle assembly central Mucin PF01456.17 ORY52282.1 - 0.47 10.4 24.7 0.89 9.5 24.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Glyoxalase PF00903.25 ORY52284.1 - 1.6e-11 44.5 0.0 2e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 ORY52284.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 ORY52284.1 - 0.15 12.9 0.0 0.18 12.6 0.0 1.1 1 0 0 1 1 1 0 Glyoxalase-like domain PBP_like_2 PF12849.7 ORY52286.1 - 1.1e-18 67.9 2.1 1.5e-18 67.4 2.1 1.1 1 0 0 1 1 1 1 PBP superfamily domain 7tm_3 PF00003.22 ORY52286.1 - 0.0035 17.1 3.3 0.0079 15.9 3.3 1.6 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR EGF PF00008.27 ORY52286.1 - 0.0055 17.0 2.7 0.012 15.9 2.7 1.5 1 0 0 1 1 1 1 EGF-like domain 7tm_3 PF00003.22 ORY52287.1 - 1e-20 74.5 20.9 1.8e-20 73.7 20.9 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR PBP_like_2 PF12849.7 ORY52287.1 - 4.9e-18 65.8 5.2 8.8e-18 65.0 5.2 1.4 1 0 0 1 1 1 1 PBP superfamily domain DUF2298 PF10060.9 ORY52287.1 - 0.052 12.3 8.3 0.089 11.5 8.3 1.3 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) EGF PF00008.27 ORY52287.1 - 0.092 13.1 3.4 0.19 12.1 3.4 1.4 1 0 0 1 1 1 0 EGF-like domain Skp1 PF01466.19 ORY52288.1 - 2.9e-28 97.7 0.9 2.9e-28 97.7 0.9 1.9 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 ORY52288.1 - 2.1e-24 85.5 1.7 3.5e-24 84.7 0.3 2.1 2 1 1 3 3 3 1 Skp1 family, tetramerisation domain DUF4649 PF15507.6 ORY52289.1 - 0.041 13.9 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4649) Cyclin_N PF00134.23 ORY52290.1 - 5.1e-07 29.5 0.0 8.4e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain eIF2_C PF09173.11 ORY52291.1 - 1.7e-33 114.7 0.3 1.7e-33 114.7 0.3 2.2 3 0 0 3 3 3 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 ORY52291.1 - 1.6e-23 83.2 0.3 4.5e-23 81.8 0.3 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 ORY52291.1 - 1e-10 41.8 1.3 2.6e-10 40.5 1.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 ORY52291.1 - 0.0012 18.8 0.4 0.022 14.7 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 ORY52291.1 - 0.0043 17.1 0.0 0.009 16.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 ORY52291.1 - 0.013 15.5 0.1 0.031 14.3 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Dynamin_N PF00350.23 ORY52291.1 - 0.12 12.4 0.2 0.42 10.7 0.2 2.0 1 1 0 1 1 1 0 Dynamin family Vert_HS_TF PF06546.11 ORY52291.1 - 0.13 12.0 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Vertebrate heat shock transcription factor GnRH PF00446.17 ORY52293.1 - 1.1 9.8 8.5 1e+03 0.6 0.0 7.8 7 0 0 7 7 7 0 Gonadotropin-releasing hormone SnoaL_2 PF12680.7 ORY52294.1 - 0.066 13.9 0.0 0.11 13.1 0.0 1.5 1 1 0 1 1 1 0 SnoaL-like domain COX16 PF14138.6 ORY52295.1 - 5.8e-26 90.8 0.2 7.1e-26 90.5 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 BPL_LplA_LipB PF03099.19 ORY52296.1 - 0.00011 22.1 0.2 0.00072 19.5 0.0 2.4 3 1 0 3 3 3 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.9 ORY52296.1 - 0.00067 19.6 0.0 0.0013 18.7 0.0 1.6 1 1 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus DUF716 PF04819.12 ORY52297.1 - 0.0064 16.1 1.0 0.032 13.9 0.1 2.0 2 0 0 2 2 2 1 Family of unknown function (DUF716) PAP1 PF08601.10 ORY52297.1 - 0.51 10.0 2.8 0.59 9.8 2.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Med3 PF11593.8 ORY52297.1 - 0.74 8.9 19.9 0.86 8.7 19.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PAP_assoc PF03828.19 ORY52298.1 - 3.3e-08 33.6 0.0 7.8e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 Cid1 family poly A polymerase tRNA_NucTransf2 PF09249.11 ORY52298.1 - 0.018 15.2 0.0 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 tRNA nucleotidyltransferase, second domain Nrap_D2 PF17403.2 ORY52298.1 - 0.037 13.8 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain OAS1_C PF10421.9 ORY52298.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus Homeodomain PF00046.29 ORY52299.1 - 7.4e-13 48.1 0.2 1.8e-12 46.9 0.2 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY52299.1 - 0.0032 17.3 0.0 0.0092 15.9 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain Spt5_N PF11942.8 ORY52299.1 - 2.5 9.1 9.6 5.6 8.0 9.6 1.6 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Homeodomain PF00046.29 ORY52300.1 - 3.3e-28 97.3 8.9 5.7e-15 54.9 2.7 2.4 2 0 0 2 2 2 2 Homeodomain Homeobox_KN PF05920.11 ORY52300.1 - 5.6e-07 29.4 8.3 0.00027 20.8 0.0 3.4 3 0 0 3 3 3 2 Homeobox KN domain HOCHOB PF17943.1 ORY52300.1 - 4.8e-05 24.1 0.1 0.17 12.6 0.0 2.3 2 0 0 2 2 2 2 Homeobox-cysteine loop-homeobox CDP-OH_P_transf PF01066.21 ORY52301.1 - 1.8e-08 35.0 0.3 1.8e-08 35.0 0.3 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Homeodomain PF00046.29 ORY52302.1 - 3.6e-15 55.6 0.4 3.6e-15 55.6 0.4 2.0 2 0 0 2 2 2 1 Homeodomain Homez PF11569.8 ORY52302.1 - 0.0018 17.7 0.1 0.0048 16.3 0.1 1.7 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez PSP PF04046.16 ORY52302.1 - 0.0092 15.8 0.2 2.2 8.2 0.0 2.4 2 0 0 2 2 2 2 PSP Homeobox_KN PF05920.11 ORY52302.1 - 0.015 15.2 2.0 0.071 13.0 0.1 2.7 2 0 0 2 2 2 0 Homeobox KN domain Homeodomain PF00046.29 ORY52303.1 - 4.2e-05 23.3 0.1 0.00011 21.9 0.1 1.8 2 0 0 2 2 2 1 Homeodomain Homeodomain PF00046.29 ORY52304.1 - 4.1e-14 52.2 3.1 7.4e-14 51.3 3.1 1.5 1 0 0 1 1 1 1 Homeodomain Homez PF11569.8 ORY52304.1 - 0.0077 15.7 0.0 0.029 13.8 0.0 2.0 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.11 ORY52304.1 - 0.037 13.9 0.2 0.1 12.5 0.2 1.7 1 0 0 1 1 1 0 Homeobox KN domain Homeodomain PF00046.29 ORY52305.1 - 3.5e-12 46.0 0.8 7.8e-12 44.9 0.8 1.6 1 0 0 1 1 1 1 Homeodomain Homeodomain PF00046.29 ORY52306.1 - 3.9e-13 49.0 0.6 8.7e-13 47.9 0.6 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY52306.1 - 0.016 15.1 0.0 0.05 13.5 0.0 1.9 1 0 0 1 1 1 0 Homeobox KN domain DUF3887 PF13026.6 ORY52306.1 - 0.049 14.4 0.0 0.099 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) Homeodomain PF00046.29 ORY52307.1 - 3.7e-11 42.7 1.0 9.3e-11 41.4 1.0 1.7 1 0 0 1 1 1 1 Homeodomain SusD-like_2 PF12771.7 ORY52307.1 - 0.065 12.2 0.0 0.083 11.8 0.0 1.1 1 0 0 1 1 1 0 Starch-binding associating with outer membrane Sigma70_r4 PF04545.16 ORY52307.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Homeodomain PF00046.29 ORY52308.1 - 3.9e-10 39.4 0.6 5.9e-10 38.8 0.6 1.2 1 0 0 1 1 1 1 Homeodomain Homeodomain PF00046.29 ORY52309.1 - 2.9e-09 36.6 0.1 1.2e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 Homeodomain Homeodomain PF00046.29 ORY52310.1 - 2.2e-15 56.2 0.3 4.6e-15 55.2 0.3 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY52310.1 - 6.8e-06 25.9 1.2 1e-05 25.3 0.1 1.9 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.8 ORY52310.1 - 0.035 13.6 0.0 0.084 12.3 0.0 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez YdaS_antitoxin PF15943.5 ORY52310.1 - 0.054 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Sigma70_r3 PF04539.16 ORY52310.1 - 0.16 12.1 0.1 0.92 9.6 0.0 2.1 2 0 0 2 2 2 0 Sigma-70 region 3 Homeodomain PF00046.29 ORY52311.1 - 8.5e-10 38.3 0.0 1.6e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY52311.1 - 0.0037 17.1 0.0 0.0097 15.8 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 ORY52312.1 - 2e-09 37.1 0.0 4e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Homeodomain HTH_23 PF13384.6 ORY52312.1 - 0.0078 16.0 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_IclR PF09339.10 ORY52312.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain Sigma70_r4_2 PF08281.12 ORY52312.1 - 0.013 15.1 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_3 PF01381.22 ORY52312.1 - 0.032 14.3 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix HTH_36 PF13730.6 ORY52312.1 - 0.049 13.6 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_24 PF13412.6 ORY52312.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Terminase_5 PF06056.12 ORY52312.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) Phage_CI_repr PF07022.13 ORY52312.1 - 0.18 11.9 0.0 0.28 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage CI repressor helix-turn-helix domain Homeodomain PF00046.29 ORY52313.1 - 2.8e-13 49.5 0.0 7.1e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY52313.1 - 0.023 14.6 0.0 0.08 12.9 0.0 1.9 1 0 0 1 1 1 0 Homeobox KN domain Homeodomain PF00046.29 ORY52314.1 - 2.4e-15 56.1 1.4 5.6e-15 54.9 1.4 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY52314.1 - 6.9e-05 22.7 0.3 6.9e-05 22.7 0.3 2.1 2 0 0 2 2 2 1 Homeobox KN domain SelP_N PF04592.14 ORY52314.1 - 4.1 6.7 20.5 9.7 5.5 20.5 1.7 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF1917 PF08939.10 ORY52314.1 - 4.9 7.0 10.2 5.3 6.9 9.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1917) Homeodomain PF00046.29 ORY52315.1 - 2.3e-09 37.0 0.0 5.2e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Homeodomain LRR_6 PF13516.6 ORY52316.1 - 6.7e-08 32.0 9.1 0.0034 17.3 0.0 5.3 5 0 0 5 5 5 4 Leucine Rich repeat Homeodomain PF00046.29 ORY52317.1 - 4.4e-15 55.3 0.1 7.8e-15 54.5 0.1 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY52317.1 - 1.8e-05 24.5 0.0 4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Homeobox KN domain PilO PF04350.13 ORY52317.1 - 0.034 14.3 0.3 0.64 10.2 0.0 2.1 2 0 0 2 2 2 0 Pilus assembly protein, PilO Homeodomain PF00046.29 ORY52318.1 - 4.9e-11 42.3 0.1 8.4e-11 41.6 0.1 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY52318.1 - 0.00099 19.0 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 Homeobox KN domain Oest_recep PF02159.15 ORY52318.1 - 0.077 13.5 0.5 0.21 12.1 0.5 1.7 1 0 0 1 1 1 0 Oestrogen receptor Galactosyl_T PF01762.21 ORY52319.1 - 1.4e-08 34.8 0.2 0.0017 18.2 0.4 2.7 1 1 1 2 2 2 2 Galactosyltransferase Galactosyl_T PF01762.21 ORY52320.1 - 9.1e-09 35.4 0.2 6.2e-05 22.9 0.1 2.8 1 1 0 2 2 2 2 Galactosyltransferase Fringe PF02434.16 ORY52320.1 - 0.015 14.8 0.0 0.031 13.7 0.0 1.6 2 0 0 2 2 2 0 Fringe-like Galactosyl_T PF01762.21 ORY52321.1 - 2.2e-09 37.4 0.5 0.0003 20.6 0.3 2.9 1 1 1 2 2 2 2 Galactosyltransferase Fringe PF02434.16 ORY52321.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Fringe-like Galactosyl_T PF01762.21 ORY52322.1 - 5e-10 39.5 0.0 2e-05 24.5 0.0 2.8 1 1 1 2 2 2 2 Galactosyltransferase Mlh1_C PF16413.5 ORY52322.1 - 0.026 13.9 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus Fringe PF02434.16 ORY52322.1 - 0.043 13.3 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 Fringe-like Galactosyl_T PF01762.21 ORY52323.1 - 1.4e-11 44.5 0.2 5.7e-05 23.0 0.2 2.8 1 1 1 2 2 2 2 Galactosyltransferase DUF4646 PF15496.6 ORY52323.1 - 0.021 15.4 0.2 0.053 14.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) Fringe PF02434.16 ORY52323.1 - 0.1 12.0 0.0 0.28 10.6 0.0 1.7 1 1 0 1 1 1 0 Fringe-like Homeodomain PF00046.29 ORY52324.1 - 3.4e-14 52.4 0.8 6.1e-14 51.6 0.2 1.8 2 0 0 2 2 2 1 Homeodomain Homeobox_KN PF05920.11 ORY52324.1 - 0.00026 20.8 0.1 0.00054 19.8 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 ORY52324.1 - 0.5 10.3 2.1 4 7.4 0.0 2.6 3 0 0 3 3 3 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Hamartin PF04388.12 ORY52324.1 - 2 7.0 5.7 2.2 6.8 5.7 1.1 1 0 0 1 1 1 0 Hamartin protein Homeodomain PF00046.29 ORY52325.1 - 1.4e-15 56.9 0.1 2.6e-15 56.0 0.1 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY52325.1 - 2.2e-06 27.4 0.3 2.2e-06 27.4 0.3 1.9 2 0 0 2 2 2 1 Homeobox KN domain YdaS_antitoxin PF15943.5 ORY52325.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Homeodomain PF00046.29 ORY52326.1 - 1.7e-23 82.2 7.7 1.4e-12 47.3 0.3 2.8 3 0 0 3 3 3 2 Homeodomain Homeobox_KN PF05920.11 ORY52326.1 - 5.1e-06 26.3 1.0 0.12 12.3 0.2 2.6 2 0 0 2 2 2 2 Homeobox KN domain Radial_spoke PF04712.12 ORY52327.1 - 4.2e-137 458.1 0.0 4.2e-137 458.1 0.0 1.9 1 1 1 2 2 2 1 Radial spokehead-like protein Homeodomain PF00046.29 ORY52328.1 - 1.9e-15 56.5 0.2 3.3e-15 55.6 0.2 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY52328.1 - 0.083 12.8 0.3 0.17 11.8 0.3 1.7 1 1 0 1 1 1 0 Homeobox KN domain HTH_48 PF17906.1 ORY52328.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 HTH domain in Mos1 transposase Homeodomain PF00046.29 ORY52329.1 - 2.2e-12 46.6 0.9 4.7e-12 45.6 0.9 1.6 1 0 0 1 1 1 1 Homeodomain Terminase_5 PF06056.12 ORY52329.1 - 0.0024 17.7 0.1 0.51 10.3 0.1 2.3 2 0 0 2 2 2 2 Putative ATPase subunit of terminase (gpP-like) HTH_23 PF13384.6 ORY52329.1 - 0.0057 16.4 0.0 0.045 13.5 0.1 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_48 PF17906.1 ORY52329.1 - 0.16 12.1 0.0 0.34 11.1 0.0 1.5 1 0 0 1 1 1 0 HTH domain in Mos1 transposase Homeodomain PF00046.29 ORY52330.1 - 8.7e-17 60.7 0.4 2e-16 59.6 0.4 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY52330.1 - 1e-06 28.5 0.1 2.5e-06 27.3 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 ORY52331.1 - 1.3e-16 60.1 1.5 1.5e-16 59.9 1.5 1.1 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY52331.1 - 7.8e-07 28.9 0.1 1.1e-06 28.4 0.1 1.2 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 ORY52331.1 - 0.0016 18.3 0.0 0.0021 17.9 0.0 1.1 1 0 0 1 1 1 1 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT EF-hand_7 PF13499.6 ORY52332.1 - 0.0035 17.8 0.1 0.013 16.0 0.1 2.1 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 ORY52332.1 - 0.035 13.6 0.1 0.078 12.5 0.1 1.5 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 ORY52332.1 - 0.076 12.6 0.2 0.41 10.3 0.0 2.2 2 0 0 2 2 2 0 EF hand DUF1062 PF06353.12 ORY52332.1 - 0.12 13.2 0.2 0.2 12.5 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1062) p25-alpha PF05517.12 ORY52335.1 - 1.1e-38 132.9 0.3 1.4e-38 132.5 0.3 1.0 1 0 0 1 1 1 1 p25-alpha EF-hand_7 PF13499.6 ORY52335.1 - 0.0038 17.6 0.2 0.0089 16.5 0.2 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 ORY52335.1 - 0.058 13.2 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair Peptidase_S8 PF00082.22 ORY52336.1 - 7.9e-38 130.4 6.8 1.1e-37 129.9 6.8 1.1 1 0 0 1 1 1 1 Subtilase family DUF2075 PF09848.9 ORY52336.1 - 0.023 13.9 0.1 0.035 13.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SSP160 PF06933.11 ORY52338.1 - 0.03 12.5 19.3 0.032 12.4 19.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FliD_N PF02465.18 ORY52338.1 - 0.052 14.3 3.5 0.083 13.6 3.5 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus ATG11 PF10377.9 ORY52339.1 - 4.8e-17 62.2 0.0 1.9e-16 60.3 0.0 2.1 1 0 0 1 1 1 1 Autophagy-related protein 11 ATG16 PF08614.11 ORY52339.1 - 0.0032 17.7 72.4 0.0043 17.3 9.4 7.0 5 3 1 6 6 6 2 Autophagy protein 16 (ATG16) SLATT_fungal PF18142.1 ORY52339.1 - 0.0072 16.3 1.9 0.073 13.1 0.0 3.6 3 0 0 3 3 3 1 SMODS and SLOG-associating 2TM effector domain Closter_coat PF01785.17 ORY52339.1 - 0.066 12.5 2.2 0.15 11.3 2.2 1.5 1 0 0 1 1 1 0 Closterovirus coat protein Mto2_bdg PF12808.7 ORY52339.1 - 0.11 12.8 0.2 0.11 12.8 0.2 4.7 5 0 0 5 5 5 0 Micro-tubular organiser Mto1 C-term Mto2-binding region RILP PF11461.8 ORY52339.1 - 0.48 10.7 7.0 0.044 14.0 1.0 2.4 2 0 0 2 2 2 0 Rab interacting lysosomal protein TACC_C PF05010.14 ORY52339.1 - 3.2 7.5 37.9 0.06 13.1 19.6 3.6 3 0 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Cu-oxidase_2 PF07731.14 ORY52340.1 - 7.9e-20 71.0 0.3 2.7e-17 62.8 0.1 2.1 1 1 1 2 2 2 2 Multicopper oxidase Suc_Fer-like PF06999.12 ORY52341.1 - 4.6e-27 95.2 0.0 3.6e-15 56.4 0.0 2.2 2 0 0 2 2 2 2 Sucrase/ferredoxin-like CFEM PF05730.11 ORY52343.1 - 0.0039 17.3 0.7 0.0056 16.8 0.7 1.3 1 0 0 1 1 1 1 CFEM domain CFEM PF05730.11 ORY52344.1 - 0.012 15.7 12.7 0.099 12.8 4.2 2.6 2 0 0 2 2 2 0 CFEM domain UCH PF00443.29 ORY52345.1 - 5.1e-31 108.1 0.0 1.8e-30 106.3 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 ORY52345.1 - 4.7e-07 29.7 0.3 0.0012 18.5 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 ORY52345.1 - 0.0038 17.1 0.0 0.007 16.3 0.0 1.5 1 0 0 1 1 1 1 A repeated domain in UCH-protein Flp_N PF03930.14 ORY52345.1 - 0.14 12.1 0.1 0.42 10.6 0.1 1.8 2 0 0 2 2 2 0 Recombinase Flp protein N-terminus LRR_8 PF13855.6 ORY52346.1 - 8.1e-18 63.9 1.2 6.4e-05 22.6 0.7 4.7 2 1 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 ORY52346.1 - 2.7e-11 43.5 3.6 0.00062 20.1 0.1 4.9 4 1 0 5 5 5 3 Leucine Rich repeats (2 copies) F-box PF00646.33 ORY52346.1 - 5.5e-06 26.1 1.9 6.3e-06 25.9 0.4 1.9 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 ORY52346.1 - 4.4e-05 23.5 11.5 0.03 14.8 0.6 7.1 7 1 1 8 8 8 1 Leucine Rich Repeat LRR_6 PF13516.6 ORY52346.1 - 0.00042 20.1 6.8 0.11 12.6 0.1 5.5 6 0 0 6 6 6 1 Leucine Rich repeat MitoNEET_N PF10660.9 ORY52346.1 - 0.0057 16.6 0.1 3 7.9 0.1 3.9 3 1 1 4 4 4 1 Iron-containing outer mitochondrial membrane protein N-terminus F-box-like PF12937.7 ORY52346.1 - 0.0087 15.9 0.7 0.0087 15.9 0.7 2.0 2 0 0 2 2 2 1 F-box-like LRR_9 PF14580.6 ORY52346.1 - 0.062 12.8 0.0 0.44 10.0 0.0 2.0 2 0 0 2 2 2 0 Leucine-rich repeat Peptidase_M1 PF01433.20 ORY52348.1 - 2.5e-83 279.0 1.5 4.9e-83 278.0 1.5 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 ORY52348.1 - 6.9e-55 186.8 1.5 2.2e-54 185.1 0.7 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 ORY52348.1 - 1.6e-45 155.6 2.6 2.3e-45 155.1 1.5 1.8 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Yae1_N PF09811.9 ORY52349.1 - 1.6e-09 37.3 0.8 2.2e-09 36.8 0.8 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal CFEM PF05730.11 ORY52350.1 - 0.012 15.7 1.7 0.012 15.7 1.7 2.1 2 0 0 2 2 2 0 CFEM domain Ribosomal_L29 PF00831.23 ORY52351.1 - 8.5e-13 48.1 4.8 8.5e-13 48.1 4.8 2.7 1 1 1 2 2 2 1 Ribosomal L29 protein MRP-L47 PF06984.13 ORY52351.1 - 0.0032 17.5 1.5 0.007 16.5 1.5 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) TraF_2 PF13729.6 ORY52351.1 - 0.014 14.8 0.1 0.016 14.6 0.1 1.1 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein SOGA PF11365.8 ORY52351.1 - 0.2 12.8 5.1 0.21 12.8 2.4 2.0 1 1 0 2 2 2 0 Protein SOGA Antimicrobial18 PF08130.11 ORY52351.1 - 0.44 10.7 3.4 0.48 10.6 0.1 2.3 2 1 0 2 2 2 0 Type A lantibiotic family RBM39linker PF15519.6 ORY52351.1 - 0.51 11.4 2.8 0.74 10.9 2.8 1.6 1 1 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein Snapin_Pallidin PF14712.6 ORY52351.1 - 0.74 10.3 12.3 0.34 11.4 6.8 2.1 1 1 1 2 2 2 0 Snapin/Pallidin PRKG1_interact PF15898.5 ORY52351.1 - 1.3 10.0 9.4 15 6.5 9.3 2.1 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain YlqD PF11068.8 ORY52351.1 - 1.3 9.4 8.6 4.2 7.7 8.6 1.8 1 1 0 1 1 1 0 YlqD protein Prefoldin PF02996.17 ORY52351.1 - 2.4 8.1 8.2 16 5.4 1.7 2.9 1 1 2 3 3 3 0 Prefoldin subunit CFEM PF05730.11 ORY52352.1 - 1.1e-08 35.0 10.9 8.5e-05 22.6 2.3 2.6 2 1 0 2 2 2 2 CFEM domain Pkinase PF00069.25 ORY52353.1 - 1.9e-40 138.9 1.5 4.7e-33 114.7 0.0 2.6 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY52353.1 - 4.6e-16 58.9 0.2 2.3e-10 40.2 0.0 3.3 2 1 1 3 3 3 2 Protein tyrosine kinase GET2 PF08690.10 ORY52353.1 - 0.001 18.8 2.0 0.001 18.8 2.0 1.9 2 0 0 2 2 2 1 GET complex subunit GET2 Pox_ser-thr_kin PF05445.11 ORY52353.1 - 0.0038 16.3 0.1 0.0056 15.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase CRAL_TRIO PF00650.20 ORY52354.1 - 2.5e-35 121.5 0.5 3.5e-34 117.8 0.5 2.1 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 ORY52354.1 - 5.5e-06 26.6 0.0 8.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORY52354.1 - 0.00025 21.2 0.1 0.00045 20.3 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.20 ORY52355.1 - 6.6e-22 77.9 0.0 4e-19 68.9 0.0 2.1 2 0 0 2 2 2 2 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 ORY52355.1 - 8.6e-07 29.2 0.0 1.5e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 ORY52356.1 - 1e-31 109.8 0.0 4.3e-29 101.3 0.0 2.3 2 0 0 2 2 2 2 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 ORY52356.1 - 2e-05 24.7 0.4 0.018 15.3 0.4 2.4 2 0 0 2 2 2 2 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 ORY52356.1 - 0.013 15.6 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Forkhead_N PF08430.12 ORY52356.1 - 0.52 10.9 3.2 1.1 9.8 3.2 1.5 1 0 0 1 1 1 0 Forkhead N-terminal region DUF4200 PF13863.6 ORY52357.1 - 5.3e-34 117.2 23.1 5.3e-34 117.2 23.1 5.1 3 1 1 4 4 4 1 Domain of unknown function (DUF4200) Baculo_PEP_C PF04513.12 ORY52357.1 - 0.00065 19.8 10.4 0.0026 17.8 5.0 2.9 2 1 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus RNase_J_C PF17770.1 ORY52357.1 - 0.1 13.7 0.0 0.1 13.7 0.0 4.3 3 1 1 4 4 4 0 Ribonuclease J C-terminal domain 2OG-FeII_Oxy_3 PF13640.6 ORY52358.1 - 3.8e-07 30.9 0.0 7.9e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Lipoprotein_3 PF00938.17 ORY52359.1 - 0.033 14.4 0.1 0.052 13.7 0.1 1.3 1 0 0 1 1 1 0 Lipoprotein Trp_syntA PF00290.20 ORY52360.1 - 1.9e-89 299.0 0.3 3.5e-89 298.1 0.3 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 ORY52360.1 - 5.3e-17 62.2 0.7 7.8e-11 41.9 0.1 4.1 3 1 0 3 3 3 2 Pyridoxal-phosphate dependent enzyme PTH2 PF01981.16 ORY52360.1 - 7.4e-14 52.0 0.4 1.6e-13 50.9 0.1 1.8 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 His_biosynth PF00977.21 ORY52360.1 - 0.021 14.3 0.1 0.048 13.1 0.1 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein Meckelin PF09773.9 ORY52361.1 - 1.2e-19 70.0 4.1 1.3e-19 69.8 4.1 1.0 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) Ephrin_rec_like PF07699.13 ORY52361.1 - 0.0093 15.7 7.0 0.0093 15.7 7.0 3.3 3 1 1 4 4 4 1 Putative ephrin-receptor like NCD3G PF07562.14 ORY52361.1 - 0.23 11.5 7.4 0.15 12.0 4.6 2.2 1 1 1 2 2 2 0 Nine Cysteines Domain of family 3 GPCR Meckelin PF09773.9 ORY52362.1 - 2.8e-114 383.0 8.1 3.6e-114 382.7 8.1 1.0 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) CDC27 PF09507.10 ORY52363.1 - 3.1e-42 145.5 36.8 5.1e-40 138.2 36.8 2.0 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 tRNA-synt_1g PF09334.11 ORY52364.1 - 1.2e-143 478.6 0.1 1.5e-143 478.2 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 ORY52364.1 - 1.1e-07 30.6 0.9 7.3e-05 21.2 0.0 3.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) WHEP-TRS PF00458.20 ORY52364.1 - 1.6e-05 24.9 4.2 3.5e-05 23.9 4.2 1.6 1 0 0 1 1 1 1 WHEP-TRS domain tRNA-synt_1e PF01406.19 ORY52364.1 - 0.011 15.1 0.0 0.071 12.4 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Mito_carr PF00153.27 ORY52365.1 - 1.5e-50 169.1 3.7 3.9e-17 61.9 0.2 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Ank_2 PF12796.7 ORY52366.1 - 4.4e-18 65.7 0.0 5.1e-10 39.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY52366.1 - 2.4e-13 50.0 2.6 6.1e-06 26.4 0.1 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY52366.1 - 1.1e-11 45.0 0.3 5.5e-07 30.0 0.1 3.7 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 ORY52366.1 - 1.9e-10 40.7 0.2 0.0015 18.9 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 ORY52366.1 - 6.5e-10 38.4 0.0 0.06 13.9 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Snapin_Pallidin PF14712.6 ORY52367.1 - 5.9e-05 23.4 3.1 0.00011 22.5 3.1 1.5 1 0 0 1 1 1 1 Snapin/Pallidin Ank_5 PF13857.6 ORY52367.1 - 8.4e-05 22.8 0.9 0.56 10.6 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY52367.1 - 0.0049 17.4 0.1 0.034 14.7 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF2730 PF10805.8 ORY52367.1 - 0.02 15.0 0.7 0.047 13.8 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DivIC PF04977.15 ORY52367.1 - 0.029 14.1 1.6 0.046 13.5 0.3 2.0 2 0 0 2 2 2 0 Septum formation initiator Macoilin PF09726.9 ORY52367.1 - 0.075 11.6 5.7 0.018 13.6 2.5 1.5 2 0 0 2 2 2 0 Macoilin family Ank_3 PF13606.6 ORY52367.1 - 0.15 12.7 2.2 0.32 11.7 0.2 2.7 2 0 0 2 2 2 0 Ankyrin repeat Csm1_N PF18504.1 ORY52367.1 - 0.19 12.1 3.4 0.29 11.5 1.4 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain GBP_C PF02841.14 ORY52367.1 - 0.65 9.3 3.0 0.63 9.4 1.1 1.7 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain Fib_alpha PF08702.10 ORY52367.1 - 1.1 9.5 6.5 1.1 9.5 3.8 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family KA1 PF02149.19 ORY52368.1 - 1e-10 41.2 0.1 2.1e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Pkinase PF00069.25 ORY52370.1 - 7.1e-71 238.7 0.0 7.9e-71 238.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY52370.1 - 3.6e-44 151.0 0.0 4.4e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY52370.1 - 1.2e-07 31.4 0.0 2.6e-07 30.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORY52370.1 - 0.00014 21.9 0.2 0.00089 19.2 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 ORY52370.1 - 0.00016 21.1 0.1 0.00073 18.9 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 ORY52370.1 - 0.00049 19.0 0.0 0.00065 18.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY52370.1 - 0.0018 17.3 0.0 0.0027 16.7 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 ORY52370.1 - 0.0019 17.9 0.1 0.0038 16.9 0.1 1.5 1 1 1 2 2 2 1 RIO1 family Choline_kinase PF01633.20 ORY52370.1 - 0.029 13.9 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 ORY52372.1 - 0.00043 19.7 0.0 0.00051 19.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 ORY52373.1 - 4.3e-20 72.2 0.2 4.6e-20 72.1 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY52373.1 - 6.4e-13 48.6 0.3 7.4e-13 48.4 0.3 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 ORY52374.1 - 2.1e-66 224.0 0.0 3.9e-66 223.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY52374.1 - 6.4e-37 127.2 0.0 9.5e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 ORY52374.1 - 7.8e-09 35.2 0.0 1.4e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 ORY52374.1 - 6.2e-06 25.7 0.0 1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY52374.1 - 0.0012 18.2 0.1 0.0021 17.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY52374.1 - 0.0016 17.4 0.2 0.0039 16.2 0.2 1.6 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY52374.1 - 0.0045 16.9 0.1 0.0083 16.1 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 ORY52374.1 - 0.0081 15.8 0.7 0.03 13.9 0.0 2.3 3 0 0 3 3 3 1 RIO1 family Sld5 PF05916.11 ORY52375.1 - 7e-05 23.3 0.0 0.00011 22.7 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein DUF3375 PF11855.8 ORY52375.1 - 0.086 11.7 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) PTPlike_phytase PF14566.6 ORY52376.1 - 8e-138 454.9 0.3 1.9e-47 161.2 0.0 3.5 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.20 ORY52376.1 - 6.5e-09 35.7 0.0 0.14 12.0 0.0 3.7 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY52376.1 - 0.00015 21.4 0.0 1.5 8.3 0.0 3.2 3 0 0 3 3 3 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 ORY52376.1 - 0.0044 17.0 0.0 0.16 11.9 0.0 2.8 3 0 0 3 3 3 1 Tyrosine phosphatase family Mtr2 PF10429.9 ORY52376.1 - 0.17 11.8 0.1 0.47 10.4 0.0 1.7 2 0 0 2 2 2 0 Nuclear pore RNA shuttling protein Mtr2 CaMKII_AD PF08332.10 ORY52378.1 - 2e-27 95.9 0.0 2.4e-27 95.6 0.0 1.0 1 0 0 1 1 1 1 Calcium/calmodulin dependent protein kinase II association domain SnoaL_3 PF13474.6 ORY52378.1 - 0.016 15.5 0.2 0.025 14.8 0.2 1.6 1 1 0 1 1 1 0 SnoaL-like domain DUF3303 PF11746.8 ORY52379.1 - 0.12 12.6 0.8 0.26 11.6 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3303) Thioredoxin_8 PF13905.6 ORY52380.1 - 9.7e-20 70.7 0.0 1.6e-14 54.0 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin PF00085.20 ORY52380.1 - 2.1e-05 24.4 0.0 8.5e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 ORY52380.1 - 0.0006 19.7 0.0 0.033 14.1 0.0 3.0 3 1 0 3 3 3 1 AhpC/TSA family 7TMR-HDED PF07697.11 ORY52380.1 - 0.0059 16.8 1.2 0.012 15.8 1.2 1.4 1 0 0 1 1 1 1 7TM-HD extracellular Thioredoxin_2 PF13098.6 ORY52380.1 - 0.072 13.5 0.7 1.6 9.2 0.0 2.9 3 1 0 3 3 3 0 Thioredoxin-like domain Proteasom_Rpn13 PF04683.13 ORY52380.1 - 0.12 12.9 0.0 0.32 11.5 0.0 1.7 1 0 0 1 1 1 0 Proteasome complex subunit Rpn13 ubiquitin receptor Pap_E4 PF02711.14 ORY52380.1 - 0.66 11.0 4.9 1.3 10.0 4.9 1.5 1 0 0 1 1 1 0 E4 protein RPA_C PF08784.11 ORY52381.1 - 5.2e-09 36.7 0.2 5.2e-09 36.7 0.2 1.8 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 ORY52381.1 - 0.0068 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain WD40 PF00400.32 ORY52382.1 - 1.4e-30 104.8 11.0 4.5e-10 39.9 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY52382.1 - 6.2e-14 52.1 1.9 0.00051 20.3 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY52382.1 - 7.6e-05 21.5 2.0 0.23 10.0 0.1 2.8 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 ORY52382.1 - 0.0001 21.2 0.3 0.035 12.9 0.0 2.8 1 1 0 2 2 2 1 Nup133 N terminal like Lgl_C PF08596.10 ORY52382.1 - 0.0068 15.1 0.0 1.9 7.1 0.0 2.2 2 0 0 2 2 2 2 Lethal giant larvae(Lgl) like, C-terminal Hira PF07569.11 ORY52382.1 - 0.053 13.2 0.0 0.46 10.2 0.0 2.3 2 1 1 3 3 3 0 TUP1-like enhancer of split VCBS PF13517.6 ORY52382.1 - 0.057 14.0 0.5 0.3 11.7 0.1 2.4 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella dsDNA_bind PF01984.20 ORY52383.1 - 5.2e-07 29.9 0.0 0.00011 22.4 0.0 2.1 2 0 0 2 2 2 2 Double-stranded DNA-binding domain FAM76 PF16046.5 ORY52384.1 - 0.0028 17.1 2.0 0.0035 16.8 2.0 1.2 1 0 0 1 1 1 1 FAM76 protein Phage_GP20 PF06810.11 ORY52384.1 - 0.11 12.3 5.7 0.17 11.7 5.7 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF3810 PF12725.7 ORY52384.1 - 0.11 11.8 0.5 0.14 11.5 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF3987 PF13148.6 ORY52384.1 - 0.13 11.2 5.6 0.19 10.7 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF3584 PF12128.8 ORY52384.1 - 0.35 8.3 18.8 0.45 8.0 18.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_11 PF13086.6 ORY52384.1 - 0.46 10.2 8.1 0.57 9.9 8.1 1.1 1 0 0 1 1 1 0 AAA domain BshC PF10079.9 ORY52384.1 - 0.66 8.7 10.6 0.82 8.3 10.6 1.0 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC DUF4175 PF13779.6 ORY52384.1 - 0.68 7.8 12.7 0.83 7.5 12.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FapA PF03961.13 ORY52384.1 - 0.93 8.0 5.9 1.2 7.7 5.9 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A APG6_N PF17675.1 ORY52384.1 - 1 9.9 16.6 1.6 9.2 16.6 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region GBP_C PF02841.14 ORY52384.1 - 1.7 7.9 16.6 2.3 7.5 16.6 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain OmpH PF03938.14 ORY52384.1 - 1.8 8.9 18.5 2.4 8.5 18.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 ORY52384.1 - 2.7 7.3 4.6 3.5 6.9 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1917 PF08939.10 ORY52384.1 - 4 7.3 8.9 8 6.3 8.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1917) Exonuc_VII_L PF02601.15 ORY52384.1 - 4.2 6.9 10.1 5.5 6.5 10.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 ORY52384.1 - 5.3 4.8 6.8 6.5 4.5 6.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Histidinol_dh PF00815.20 ORY52384.1 - 6.9 5.6 5.7 9.3 5.1 5.7 1.1 1 0 0 1 1 1 0 Histidinol dehydrogenase 5_nucleotid PF05761.14 ORY52384.1 - 9.8 4.9 10.1 12 4.6 10.1 1.0 1 0 0 1 1 1 0 5' nucleotidase family Nucleotid_trans PF03407.16 ORY52385.1 - 0.0056 16.7 0.0 0.0057 16.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase YozE_SAM_like PF06855.12 ORY52385.1 - 0.056 13.6 0.0 0.081 13.1 0.0 1.2 1 0 0 1 1 1 0 YozE SAM-like fold Fungal_trans PF04082.18 ORY52387.1 - 0.0011 18.0 0.3 0.0025 16.9 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain AAA_24 PF13479.6 ORY52387.1 - 0.019 14.7 0.1 0.034 13.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain Zn_clus PF00172.18 ORY52387.1 - 0.06 13.5 7.2 0.11 12.6 7.2 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Inj_translocase PF16928.5 ORY52387.1 - 0.99 8.8 6.5 2.1 7.8 6.5 1.4 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome RNA_pol PF00940.19 ORY52388.1 - 8e-131 436.7 0.1 5.9e-128 427.2 0.1 2.3 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 ORY52388.1 - 1.3e-63 215.5 2.6 1.3e-63 215.5 2.6 1.9 3 0 0 3 3 3 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.6 ORY52388.1 - 0.00035 20.7 0.0 0.0087 16.2 0.0 2.8 3 0 0 3 3 3 1 PPR repeat family PPR_3 PF13812.6 ORY52388.1 - 0.1 12.7 0.0 4.2 7.5 0.0 2.5 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Transglut_core PF01841.19 ORY52389.1 - 0.00031 21.2 0.2 0.00057 20.3 0.2 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Herpes_heli_pri PF05774.11 ORY52390.1 - 0.043 14.0 0.6 0.17 12.1 0.1 2.2 2 0 0 2 2 2 0 Herpesvirus helicase-primase complex component TPR_17 PF13431.6 ORY52390.1 - 0.055 13.9 0.6 1.8 9.1 0.6 2.6 1 1 0 1 1 1 0 Tetratricopeptide repeat DUF3195 PF11424.8 ORY52390.1 - 0.096 12.8 0.0 7.1 6.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3195) Asp PF00026.23 ORY52391.1 - 1.6e-51 175.6 0.1 4.1e-51 174.3 0.1 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp PF00026.23 ORY52392.1 - 4.9e-72 243.0 1.2 6.8e-72 242.5 1.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY52392.1 - 4.4e-11 43.3 0.1 2e-08 34.6 0.0 2.6 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 ORY52392.1 - 1.5e-07 31.3 0.0 3.4e-06 26.9 0.0 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Seipin PF06775.14 ORY52393.1 - 2.7e-43 148.4 2.7 4.6e-43 147.6 2.7 1.3 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Herpes_UL37_1 PF03970.13 ORY52393.1 - 0.0089 15.3 2.2 0.083 12.1 0.0 2.8 2 1 1 3 3 3 1 Herpesvirus UL37 tegument protein PepSY_TM_like_2 PF16357.5 ORY52393.1 - 0.033 14.2 3.1 0.12 12.3 0.0 2.9 4 0 0 4 4 4 0 Putative PepSY_TM-like DUF5089 PF17002.5 ORY52393.1 - 0.11 12.4 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) CPBP PF02517.16 ORY52393.1 - 1.8 9.0 7.5 4 7.9 2.0 2.3 2 0 0 2 2 2 0 CPBP intramembrane metalloprotease C2 PF00168.30 ORY52394.1 - 8e-21 74.3 0.0 2.7e-11 43.6 0.0 3.5 2 1 0 2 2 2 2 C2 domain Membr_traf_MHD PF10540.9 ORY52394.1 - 1.1e-11 45.2 0.0 2.8e-06 27.6 0.0 2.6 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain DUF1041 PF06292.17 ORY52394.1 - 0.0095 16.3 0.0 0.044 14.2 0.0 2.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1041) Rad1 PF02144.16 ORY52394.1 - 0.15 11.1 1.1 0.96 8.4 0.1 2.3 3 0 0 3 3 3 0 Repair protein Rad1/Rec1/Rad17 DUF2605 PF10792.9 ORY52394.1 - 0.73 9.8 2.8 0.89 9.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2605) Cation_ATPase_C PF00689.21 ORY52395.1 - 1.6e-42 145.3 9.9 1.6e-42 145.3 9.9 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 ORY52395.1 - 1.6e-36 125.5 0.8 1.6e-36 125.5 0.8 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 ORY52395.1 - 6.2e-17 62.6 0.0 1.4e-16 61.4 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY52395.1 - 1.4e-16 60.4 0.0 3.1e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORY52395.1 - 8.5e-10 38.2 0.0 3.6e-09 36.2 0.0 2.2 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY52395.1 - 0.012 15.4 0.1 0.54 10.0 0.1 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4231 PF14015.6 ORY52395.1 - 5 7.7 7.5 8.9 6.8 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Mannosyl_trans3 PF11051.8 ORY52396.1 - 4.4e-37 127.9 0.4 1.1e-36 126.6 0.4 1.6 1 1 0 1 1 1 1 Mannosyltransferase putative HA2 PF04408.23 ORY52397.1 - 1.2e-23 83.5 0.0 1.9e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 ORY52397.1 - 4.2e-16 59.1 0.0 1.3e-15 57.5 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold She9_MDM33 PF05546.11 ORY52398.1 - 1.1e-43 149.4 7.4 1.5e-43 149.0 7.4 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family Cytadhesin_P30 PF07271.11 ORY52398.1 - 0.016 14.8 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Cytadhesin P30/P32 Herpes_UL36 PF03586.13 ORY52398.1 - 0.044 13.1 1.2 0.061 12.6 1.2 1.2 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein NAP PF00956.18 ORY52399.1 - 5.4e-91 304.5 9.2 6.7e-91 304.2 9.2 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Mst1_SARAH PF11629.8 ORY52399.1 - 0.031 14.4 0.1 0.031 14.4 0.1 2.1 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 DUF2505 PF10698.9 ORY52399.1 - 0.1 12.7 0.1 1 9.4 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2505) FRQ PF09421.10 ORY52399.1 - 0.19 9.7 6.3 0.3 9.1 6.3 1.3 1 0 0 1 1 1 0 Frequency clock protein NusA_N PF08529.11 ORY52399.1 - 0.19 12.1 3.4 0.097 13.0 0.7 1.9 2 0 0 2 2 2 0 NusA N-terminal domain p450 PF00067.22 ORY52400.1 - 4.3e-69 233.5 0.0 5.7e-69 233.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ribosomal_L5_C PF00673.21 ORY52401.1 - 3.7e-16 59.1 0.0 7.7e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 ORY52401.1 - 0.12 12.7 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L5 AdoHcyase PF05221.17 ORY52402.1 - 8.2e-137 455.3 0.0 3.5e-74 249.7 0.3 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 ORY52402.1 - 3.8e-87 290.4 3.6 6.1e-87 289.7 3.6 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 ORY52402.1 - 9.9e-10 38.1 0.2 3e-09 36.5 0.2 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 ORY52402.1 - 9.3e-06 25.3 0.1 1.5e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 ORY52402.1 - 0.0041 17.4 0.1 0.0097 16.2 0.1 1.7 1 0 0 1 1 1 1 TrkA-N domain Enkurin PF13864.6 ORY52403.1 - 7.6e-24 84.0 4.8 1.2e-23 83.4 3.6 2.0 2 0 0 2 2 2 1 Calmodulin-binding BLOC1_2 PF10046.9 ORY52403.1 - 0.049 13.9 0.4 0.13 12.6 0.4 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Barwin PF00967.17 ORY52405.1 - 0.011 15.6 0.1 0.017 15.0 0.1 1.3 1 0 0 1 1 1 0 Barwin family DPBB_1 PF03330.18 ORY52405.1 - 0.018 15.3 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 Lytic transglycolase Cerato-platanin PF07249.12 ORY52405.1 - 0.024 14.8 0.1 0.059 13.5 0.1 1.7 1 1 0 1 1 1 0 Cerato-platanin Herpes_capsid PF06112.11 ORY52405.1 - 1 9.4 5.2 1.4 9.0 5.2 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Cerato-platanin PF07249.12 ORY52406.1 - 0.02 15.0 0.1 0.029 14.5 0.1 1.3 1 0 0 1 1 1 0 Cerato-platanin Barwin PF00967.17 ORY52406.1 - 0.028 14.3 0.2 0.052 13.4 0.2 1.5 1 0 0 1 1 1 0 Barwin family Presenilin PF01080.17 ORY52407.1 - 3.2e-100 335.7 12.1 3.2e-100 335.7 12.1 2.2 2 1 0 2 2 2 1 Presenilin zf-MYND PF01753.18 ORY52407.1 - 1.4e-08 34.7 18.2 2.9e-08 33.7 18.2 1.5 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.7 ORY52407.1 - 0.0027 18.9 12.5 0.0027 18.9 12.5 1.7 2 0 0 2 2 2 1 ECL1/2/3 zinc binding proteins Baculo_E56 PF04639.12 ORY52407.1 - 0.061 12.6 0.5 0.13 11.5 0.5 1.5 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope zf-C6H2 PF15801.5 ORY52407.1 - 2.9 8.3 15.8 5.3 7.4 15.8 1.4 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 ORY52407.1 - 3.6 7.5 16.2 1.1 9.2 13.0 1.7 2 0 0 2 2 2 0 HIT zinc finger VRR_NUC PF08774.11 ORY52408.1 - 2.9e-18 65.9 0.0 7.3e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain Pox_F12L PF03337.13 ORY52408.1 - 0.016 13.4 0.0 0.024 12.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus F12L protein TilS PF09179.11 ORY52408.1 - 0.11 12.9 0.5 2.7 8.5 0.2 2.8 2 0 0 2 2 2 0 TilS substrate binding domain DUF4570 PF15134.6 ORY52408.1 - 0.16 12.0 1.5 16 5.6 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4570) Pre-PUA PF17832.1 ORY52410.1 - 2.4e-26 92.2 0.0 3.7e-26 91.6 0.0 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 ORY52410.1 - 4.1e-17 61.9 0.1 9.4e-17 60.7 0.1 1.6 2 0 0 2 2 2 1 PUA domain Asp PF00026.23 ORY52411.1 - 5.2e-71 239.6 0.1 6.5e-71 239.3 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 ORY52411.1 - 5.3e-11 43.1 0.3 1.3e-09 38.5 0.3 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal dCMP_cyt_deam_1 PF00383.23 ORY52412.1 - 6.1e-17 61.4 0.0 7.6e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 ORY52412.1 - 2.9e-16 59.9 1.1 3.5e-12 46.7 0.1 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 ORY52412.1 - 0.006 16.2 0.9 0.22 11.1 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases zf-RING_2 PF13639.6 ORY52413.1 - 2.4e-13 50.2 5.7 3.7e-13 49.6 5.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY52413.1 - 3.3e-10 39.6 5.4 5e-10 39.1 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 ORY52413.1 - 1.9e-09 37.1 2.7 1.9e-09 37.1 2.7 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 ORY52413.1 - 3.9e-07 29.8 3.9 5.9e-07 29.2 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 ORY52413.1 - 4.6e-07 30.0 9.3 2.5e-06 27.6 9.3 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 ORY52413.1 - 1e-06 28.7 1.2 1.3e-06 28.3 0.4 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 ORY52413.1 - 3.4e-06 26.8 1.8 4.9e-06 26.3 1.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY52413.1 - 4.3e-06 26.6 2.4 6.4e-06 26.0 2.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 ORY52413.1 - 0.00026 21.0 3.5 0.00057 19.9 3.5 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 ORY52413.1 - 0.0033 17.3 3.6 0.0058 16.5 3.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 ORY52413.1 - 0.012 15.2 4.0 0.02 14.5 4.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 ORY52413.1 - 0.029 14.5 4.9 0.063 13.4 5.0 1.6 1 1 0 1 1 1 0 RING-variant domain zf-Nse PF11789.8 ORY52413.1 - 0.13 12.1 1.2 0.25 11.2 1.2 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 ORY52413.1 - 0.2 11.9 4.0 0.5 10.6 4.0 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 ORY52413.1 - 0.69 9.8 4.3 1.3 9.0 4.3 1.5 1 0 0 1 1 1 0 PHD-finger Methyltransf_34 PF11312.8 ORY52414.1 - 9.8e-46 156.4 0.0 4.1e-45 154.4 0.0 1.9 1 1 0 1 1 1 1 Putative SAM-dependent methyltransferase NNMT_PNMT_TEMT PF01234.17 ORY52414.1 - 0.0067 15.7 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family RuBisCO_large PF00016.20 ORY52414.1 - 0.026 13.7 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain p450 PF00067.22 ORY52415.1 - 1.2e-70 238.6 0.0 1.3e-70 238.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EF-hand_5 PF13202.6 ORY52415.1 - 0.14 11.7 0.2 0.3 10.7 0.2 1.5 1 0 0 1 1 1 0 EF hand p450 PF00067.22 ORY52416.1 - 3.6e-72 243.6 0.0 4.3e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 ORY52417.1 - 2.7e-44 151.0 0.1 3.6e-44 150.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY52417.1 - 1e-27 97.2 0.0 1.4e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY52417.1 - 6.5e-11 42.5 0.1 1e-10 41.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY52417.1 - 0.00086 18.8 0.0 0.0048 16.4 0.1 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 ORY52417.1 - 0.0018 17.5 0.1 0.15 11.2 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein ApbA PF02558.16 ORY52417.1 - 0.0079 15.8 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Methyltransf_31 PF13847.6 ORY52417.1 - 0.14 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Sel1 PF08238.12 ORY52418.1 - 0.00053 20.6 4.5 0.011 16.4 0.6 2.7 3 0 0 3 3 3 2 Sel1 repeat MukF_M PF17192.4 ORY52418.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 MukF middle domain GLTP PF08718.11 ORY52418.1 - 0.26 11.5 1.4 7.1 6.9 0.2 2.3 2 0 0 2 2 2 0 Glycolipid transfer protein (GLTP) CAP PF00188.26 ORY52419.1 - 4.7e-14 53.3 3.3 4.7e-14 53.3 3.3 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family zinc_ribbon_16 PF17034.5 ORY52419.1 - 0.021 15.0 0.1 0.086 13.1 0.1 2.0 1 0 0 1 1 1 0 Zinc-ribbon like family PAM2 PF07145.15 ORY52419.1 - 0.57 10.0 7.3 0.26 11.1 0.5 2.9 3 0 0 3 3 3 0 Ataxin-2 C-terminal region Dicty_REP PF05086.12 ORY52419.1 - 0.59 8.0 5.0 0.69 7.8 5.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3439 PF11921.8 ORY52419.1 - 5.7 6.9 20.3 0.98 9.4 15.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) zf-CHY PF05495.12 ORY52421.1 - 1.5e-09 38.2 11.0 1.5e-09 38.2 11.0 3.6 3 1 1 4 4 4 2 CHY zinc finger Tom22 PF04281.13 ORY52424.1 - 0.54 10.1 4.5 0.5 10.2 0.1 2.7 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 SR-25 PF10500.9 ORY52426.1 - 0.29 10.7 10.3 0.29 10.7 10.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAM199X PF15814.5 ORY52426.1 - 0.45 9.5 7.2 0.45 9.5 7.2 1.0 1 0 0 1 1 1 0 Protein family FAM199X NOT2_3_5 PF04153.18 ORY52428.1 - 9.2e-20 71.1 0.0 8.8e-17 61.4 0.0 2.1 2 0 0 2 2 2 2 NOT2 / NOT3 / NOT5 family Epimerase PF01370.21 ORY52429.1 - 2e-56 191.2 0.0 2.8e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 ORY52429.1 - 2.2e-16 60.2 0.1 3.5e-16 59.5 0.1 1.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 ORY52429.1 - 6.6e-08 32.0 0.0 1.3e-07 31.0 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 ORY52429.1 - 2.6e-05 23.4 0.0 4.6e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ORY52429.1 - 0.00073 18.8 1.3 0.0034 16.6 1.3 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein TIP120 PF08623.10 ORY52430.1 - 3.2e-56 189.7 5.4 1.2e-53 181.3 0.0 4.2 5 1 0 5 5 3 2 TATA-binding protein interacting (TIP20) HEAT_EZ PF13513.6 ORY52430.1 - 2.2e-21 75.9 9.7 0.024 15.1 0.0 10.5 9 1 1 10 10 9 4 HEAT-like repeat HEAT_2 PF13646.6 ORY52430.1 - 4.9e-17 62.1 15.1 0.0012 19.2 0.8 9.2 7 3 2 9 9 9 4 HEAT repeats HEAT PF02985.22 ORY52430.1 - 2.1e-15 55.5 14.4 0.26 11.6 0.0 11.0 11 0 0 11 11 9 4 HEAT repeat CLASP_N PF12348.8 ORY52430.1 - 4.2e-09 36.3 3.3 0.42 10.1 0.0 7.2 6 2 0 6 6 6 1 CLASP N terminal Cnd1 PF12717.7 ORY52430.1 - 2.7e-08 34.0 16.9 0.04 14.0 0.1 6.7 7 1 1 8 8 7 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 ORY52430.1 - 2.8e-07 29.5 18.8 0.00039 19.1 4.0 5.7 3 2 2 5 5 5 3 Adaptin N terminal region UME PF08064.13 ORY52430.1 - 7.4e-07 29.0 1.2 7.2 6.6 0.0 6.5 5 1 0 5 5 5 0 UME (NUC010) domain Arm PF00514.23 ORY52430.1 - 9.5e-07 28.7 4.1 0.62 10.2 0.0 7.1 7 0 0 7 7 6 1 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 ORY52430.1 - 3.8e-05 24.2 9.2 0.08 13.5 0.6 6.7 8 1 0 8 8 5 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 ORY52430.1 - 4.4e-05 22.8 24.3 0.48 9.5 0.0 8.4 7 3 1 8 8 8 1 RNAPII transcription regulator C-terminal Telomere_reg-2 PF10193.9 ORY52430.1 - 5.7e-05 23.5 9.0 0.33 11.4 0.4 5.9 5 0 0 5 5 5 1 Telomere length regulation protein DUF3385 PF11865.8 ORY52430.1 - 6e-05 23.0 3.6 2.7 7.9 0.0 5.2 6 0 0 6 6 4 2 Domain of unknown function (DUF3385) DNA_pol_phi PF04931.13 ORY52430.1 - 0.00079 17.7 18.3 0.0095 14.1 8.8 2.7 2 1 0 2 2 2 2 DNA polymerase phi RIX1 PF08167.12 ORY52430.1 - 0.001 18.9 8.9 2.2 8.0 0.0 5.3 5 0 0 5 5 5 1 rRNA processing/ribosome biogenesis RRN3 PF05327.11 ORY52430.1 - 0.0013 17.4 3.0 0.0036 15.9 3.0 1.7 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Proteasom_PSMB PF10508.9 ORY52430.1 - 0.0045 15.6 16.8 0.25 9.8 7.7 3.5 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit RTP1_C1 PF10363.9 ORY52430.1 - 0.0067 16.6 10.6 1 9.5 0.6 6.8 6 2 1 8 8 8 1 Required for nuclear transport of RNA pol II C-terminus 1 SDA1 PF05285.12 ORY52430.1 - 0.0095 15.4 1.4 0.015 14.7 1.4 1.2 1 0 0 1 1 1 1 SDA1 YL1 PF05764.13 ORY52430.1 - 0.017 15.3 3.0 0.027 14.6 3.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein MOR2-PAG1_N PF14222.6 ORY52430.1 - 0.024 13.6 0.5 4.8 6.0 0.0 3.8 4 0 0 4 4 4 0 Cell morphogenesis N-terminal HEAT_PBS PF03130.16 ORY52430.1 - 0.033 14.8 0.8 6 7.8 0.0 4.7 3 0 0 3 3 2 0 PBS lyase HEAT-like repeat HydF_dimer PF18128.1 ORY52430.1 - 0.044 13.9 0.5 0.2 11.7 0.5 2.1 1 0 0 1 1 1 0 Hydrogen maturase F dimerization domain BLM10_mid PF16507.5 ORY52430.1 - 0.099 11.3 7.7 1.1 7.8 0.5 4.2 4 1 0 5 5 5 0 Proteasome-substrate-size regulator, mid region DUF3361 PF11841.8 ORY52430.1 - 0.11 12.4 11.2 0.68 9.9 1.0 4.8 5 0 0 5 5 4 0 Domain of unknown function (DUF3361) TAF6_C PF07571.13 ORY52430.1 - 0.12 12.7 0.0 1.4 9.3 0.0 2.9 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain Nop14 PF04147.12 ORY52430.1 - 0.14 10.4 5.1 0.3 9.2 5.1 1.6 1 0 0 1 1 1 0 Nop14-like family NUC173 PF08161.12 ORY52430.1 - 0.2 11.3 2.5 15 5.1 0.0 4.3 3 0 0 3 3 3 0 NUC173 domain V-ATPase_H_C PF11698.8 ORY52430.1 - 0.74 9.9 10.6 7.4 6.7 0.4 5.8 7 1 1 8 8 6 0 V-ATPase subunit H V-ATPase_H_N PF03224.14 ORY52430.1 - 1.2 8.4 12.8 0.12 11.6 2.4 3.8 5 0 0 5 5 5 0 V-ATPase subunit H CDC45 PF02724.14 ORY52430.1 - 1.3 7.2 4.4 2 6.6 4.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Dabb PF07876.12 ORY52434.1 - 1.8e-14 54.1 0.0 2e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain CobU PF02283.16 ORY52435.1 - 4.8e-51 172.7 0.1 5.8e-51 172.4 0.1 1.1 1 0 0 1 1 1 1 Cobinamide kinase / cobinamide phosphate guanyltransferase ATPase PF06745.13 ORY52435.1 - 1.6e-06 27.6 0.5 4.3e-05 23.0 0.2 2.6 1 1 0 2 2 2 1 KaiC AAA_24 PF13479.6 ORY52435.1 - 4.3e-05 23.3 0.2 6e-05 22.9 0.2 1.1 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 ORY52435.1 - 0.0053 16.7 0.0 0.0069 16.3 0.0 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea CPT PF07931.12 ORY52435.1 - 0.0099 15.7 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 ORY52435.1 - 0.017 15.5 0.0 0.035 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 ORY52435.1 - 0.022 14.9 0.0 0.069 13.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORY52435.1 - 0.038 14.5 0.1 0.083 13.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 ORY52435.1 - 0.053 13.6 0.0 0.1 12.6 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 ORY52435.1 - 0.057 13.0 0.2 0.35 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 ORY52436.1 - 2.9e-54 183.7 43.3 5.1e-33 114.3 21.6 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 ORY52436.1 - 1.8e-51 174.2 0.0 2.3e-24 86.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 ORY52436.1 - 1.9e-14 54.2 0.0 0.0027 17.6 0.0 4.5 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORY52436.1 - 3.3e-10 40.1 0.7 0.00077 19.4 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 ORY52436.1 - 1.6e-07 30.9 2.2 0.0084 15.8 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 ORY52436.1 - 1.9e-07 31.8 0.0 0.031 14.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 ORY52436.1 - 2.3e-07 30.6 0.2 0.0081 15.7 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 ORY52436.1 - 3.7e-07 30.5 0.1 0.0036 17.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 ORY52436.1 - 8.5e-07 29.5 0.4 0.032 14.6 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 ORY52436.1 - 1.7e-05 24.4 0.1 0.094 12.1 0.0 3.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 ORY52436.1 - 3.1e-05 24.0 0.5 0.15 12.1 0.2 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 ORY52436.1 - 5.2e-05 23.5 0.3 0.52 10.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 ORY52436.1 - 0.00057 20.4 0.0 0.64 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 ORY52436.1 - 0.0016 18.6 1.3 1.6 9.0 0.2 3.6 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 ORY52436.1 - 0.0039 17.3 0.1 2.9 8.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY52436.1 - 0.0042 16.8 0.6 1 9.0 0.3 2.3 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 ORY52436.1 - 0.0062 15.4 1.8 0.34 9.7 0.5 2.4 2 0 0 2 2 2 1 Predicted ATPase of the ABC class NACHT PF05729.12 ORY52436.1 - 0.0065 16.4 2.7 0.86 9.5 0.6 2.5 2 0 0 2 2 2 1 NACHT domain Dynamin_N PF00350.23 ORY52436.1 - 0.0071 16.4 0.5 0.21 11.6 0.2 2.6 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.17 ORY52436.1 - 0.0081 16.3 2.8 0.3 11.1 0.1 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_24 PF13479.6 ORY52436.1 - 0.011 15.5 0.7 0.77 9.5 0.3 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ORY52436.1 - 0.021 14.1 0.6 6.8 5.9 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.6 ORY52436.1 - 0.025 14.3 0.2 35 4.0 0.1 3.7 4 0 0 4 4 4 0 AAA ATPase domain T2SSE PF00437.20 ORY52436.1 - 0.03 13.4 0.9 0.1 11.6 0.5 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 ORY52436.1 - 0.034 13.5 1.9 1.5 8.2 0.4 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 ORY52436.1 - 0.035 13.7 2.7 2.3 7.8 0.5 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.12 ORY52436.1 - 0.05 13.1 1.5 0.38 10.2 0.4 2.5 3 0 0 3 3 3 0 Poxvirus A32 protein ATPase PF06745.13 ORY52436.1 - 0.064 12.6 0.5 6.4 6.1 0.1 2.6 2 0 0 2 2 2 0 KaiC RNA_helicase PF00910.22 ORY52436.1 - 0.1 13.0 0.2 25 5.3 0.1 2.5 2 0 0 2 2 2 0 RNA helicase ADH_zinc_N PF00107.26 ORY52436.1 - 0.11 12.5 1.3 78 3.3 0.0 4.4 3 2 2 5 5 4 0 Zinc-binding dehydrogenase AAA_19 PF13245.6 ORY52436.1 - 0.11 12.8 1.3 1.1 9.5 0.5 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 ORY52436.1 - 0.16 12.2 0.3 32 4.8 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 ORY52436.1 - 0.17 11.8 0.3 2.6 8.0 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.9 ORY52436.1 - 0.18 11.5 0.5 2 8.2 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DLIC PF05783.11 ORY52436.1 - 0.26 10.1 0.4 0.89 8.3 0.1 1.9 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) PRK PF00485.18 ORY52436.1 - 0.29 10.8 1.3 15 5.3 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP-grasp_2 PF08442.10 ORY52437.1 - 4.7e-74 248.3 0.4 7.4e-74 247.7 0.4 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 ORY52437.1 - 8.4e-27 93.9 0.7 1.4e-26 93.1 0.7 1.4 1 0 0 1 1 1 1 CoA-ligase GARS_A PF01071.19 ORY52437.1 - 0.00054 19.8 0.1 0.0026 17.6 0.0 2.2 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.6 ORY52437.1 - 0.0011 18.8 0.8 1.2 9.0 0.1 2.7 1 1 1 2 2 2 2 Succinyl-CoA ligase like flavodoxin domain OKR_DC_1_N PF03709.15 ORY52437.1 - 0.0024 18.1 0.1 0.0055 17.0 0.1 1.6 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, N-terminal domain ATP-grasp_5 PF13549.6 ORY52437.1 - 0.0052 16.3 0.2 0.011 15.2 0.2 1.6 1 1 0 1 1 1 1 ATP-grasp domain ABC_tran PF00005.27 ORY52438.1 - 5.3e-52 176.0 0.1 5.1e-25 88.6 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC2_membrane PF01061.24 ORY52438.1 - 3e-48 164.0 42.5 2.8e-29 102.0 17.9 2.3 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.6 ORY52438.1 - 3.9e-14 53.2 0.1 0.0027 17.6 0.0 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 ORY52438.1 - 3.4e-09 36.8 0.4 0.0018 18.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 ORY52438.1 - 4.4e-08 32.8 0.4 0.014 15.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY52438.1 - 4.4e-08 33.7 0.5 0.01 16.2 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 ORY52438.1 - 4.4e-07 30.6 0.0 0.041 14.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 ORY52438.1 - 6.3e-07 29.8 0.7 0.0072 16.6 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 ORY52438.1 - 2.8e-05 23.8 0.0 0.15 11.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 ORY52438.1 - 5.2e-05 22.8 0.1 0.29 10.5 0.0 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORY52438.1 - 7.4e-05 23.0 0.2 0.48 10.7 0.1 2.9 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 ORY52438.1 - 8.1e-05 22.7 0.9 0.26 11.4 0.3 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 ORY52438.1 - 0.0014 19.2 0.0 1.7 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 ORY52438.1 - 0.0017 18.5 0.5 0.31 11.1 0.1 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_33 PF13671.6 ORY52438.1 - 0.0017 18.5 0.1 2.5 8.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 ORY52438.1 - 0.0035 17.6 3.3 1.6 9.0 0.2 3.6 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 ORY52438.1 - 0.0046 16.7 0.3 1.6 8.4 0.1 2.3 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 ORY52438.1 - 0.0046 17.0 0.9 0.1 12.7 0.2 2.4 2 0 0 2 2 2 1 Dynamin family NACHT PF05729.12 ORY52438.1 - 0.005 16.8 1.9 1.2 9.0 0.6 2.5 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 ORY52438.1 - 0.0091 15.7 0.2 0.83 9.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 ORY52438.1 - 0.011 15.0 0.2 4 6.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin T2SSE PF00437.20 ORY52438.1 - 0.011 14.8 0.1 0.054 12.6 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 ORY52438.1 - 0.011 15.0 0.3 1.2 8.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_ATPase PF09818.9 ORY52438.1 - 0.016 14.0 1.2 0.64 8.7 0.3 2.3 2 0 0 2 2 2 0 Predicted ATPase of the ABC class cobW PF02492.19 ORY52438.1 - 0.016 14.8 1.5 2.2 7.8 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 ORY52438.1 - 0.054 13.2 0.1 87 2.7 0.0 3.8 4 0 0 4 4 4 0 AAA ATPase domain DLIC PF05783.11 ORY52438.1 - 0.069 12.0 0.3 0.4 9.5 0.0 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) dNK PF01712.19 ORY52438.1 - 0.078 12.8 0.1 5.5 6.8 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase Rad17 PF03215.15 ORY52438.1 - 0.081 12.8 0.1 6 6.7 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain ABC2_membrane_3 PF12698.7 ORY52438.1 - 0.082 12.0 42.1 0.31 10.1 15.4 2.4 2 0 0 2 2 2 0 ABC-2 family transporter protein AAA_19 PF13245.6 ORY52438.1 - 0.098 13.0 0.3 1.6 9.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 ORY52438.1 - 0.1 11.9 0.2 13 5.0 0.0 2.3 2 0 0 2 2 2 0 KaiC Pox_A32 PF04665.12 ORY52438.1 - 0.1 12.0 1.0 0.92 8.9 0.2 2.5 3 0 0 3 3 3 0 Poxvirus A32 protein MobB PF03205.14 ORY52438.1 - 0.14 12.0 0.5 2 8.3 0.1 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MeaB PF03308.16 ORY52438.1 - 0.15 11.1 0.4 3.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB PRK PF00485.18 ORY52438.1 - 0.15 11.8 0.9 12 5.5 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 ORY52438.1 - 0.15 12.5 0.2 30 5.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Roc PF08477.13 ORY52438.1 - 0.16 12.2 0.1 31 4.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase COX7a PF02238.15 ORY52438.1 - 0.31 11.5 0.1 0.31 11.5 0.1 2.5 3 0 0 3 3 1 0 Cytochrome c oxidase subunit VII Ribosomal_S14 PF00253.21 ORY52439.1 - 0.0064 16.2 0.4 0.011 15.4 0.4 1.5 1 1 0 1 1 1 1 Ribosomal protein S14p/S29e SM-ATX PF14438.6 ORY52440.1 - 0.014 15.5 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain YjeF_N PF03853.15 ORY52441.1 - 5.3e-36 124.1 0.3 6.8e-36 123.7 0.3 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus DEC-1_C PF04626.13 ORY52441.1 - 0.0054 17.1 0.1 0.012 16.0 0.1 1.6 1 1 0 1 1 1 1 Dec-1 protein, C terminal region BDHCT_assoc PF16204.5 ORY52441.1 - 0.14 11.8 3.3 0.21 11.2 3.3 1.2 1 0 0 1 1 1 0 BDHCT-box associated domain on Bloom syndrome protein DUF5096 PF17019.5 ORY52441.1 - 0.21 11.3 0.0 1.1 9.0 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5096) ANF_receptor PF01094.28 ORY52442.1 - 7.6e-09 35.1 0.1 1.1e-08 34.6 0.1 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region LRR_4 PF12799.7 ORY52443.1 - 8.6e-20 70.5 36.0 1.9e-06 28.1 1.0 5.7 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY52443.1 - 3.5e-15 55.5 35.2 6.1e-08 32.3 8.7 4.6 2 2 0 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 ORY52443.1 - 1.5e-09 37.6 11.6 3.9e-07 29.7 3.0 3.4 1 1 2 3 3 3 2 Leucine-rich repeat LRR_6 PF13516.6 ORY52443.1 - 4.1e-06 26.4 25.5 2.2 8.5 0.1 7.7 8 0 0 8 8 8 5 Leucine Rich repeat LRR_1 PF00560.33 ORY52443.1 - 0.028 14.9 28.8 5.3 8.0 0.4 8.0 6 2 0 6 6 6 0 Leucine Rich Repeat DUF572 PF04502.13 ORY52443.1 - 7.7 6.0 16.8 13 5.3 16.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) DEAD PF00270.29 ORY52445.1 - 1.2e-36 126.1 0.0 2.5e-36 125.1 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 ORY52445.1 - 6.3e-07 29.5 0.0 1.1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TRIC PF05197.13 ORY52446.1 - 0.08 12.5 0.2 0.16 11.6 0.2 1.4 1 0 0 1 1 1 0 TRIC channel MBOAT PF03062.19 ORY52449.1 - 1.8e-40 139.4 10.4 5.2e-40 137.9 10.4 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Zn_clus PF00172.18 ORY52451.1 - 1.4e-14 53.9 26.6 3.3e-08 33.5 6.8 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY52451.1 - 6.8e-09 35.1 0.2 1.5e-08 34.0 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF1195 PF06708.11 ORY52451.1 - 0.033 14.0 2.3 0.033 13.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1195) Herpes_glycop_H PF02489.16 ORY52451.1 - 0.038 12.5 0.1 0.071 11.6 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus glycoprotein H main domain Fungal_trans PF04082.18 ORY52452.1 - 0.00011 21.4 0.6 0.00025 20.2 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF4718 PF15842.5 ORY52452.1 - 0.17 11.7 0.6 0.31 10.8 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4718) SAM_2 PF07647.17 ORY52453.1 - 4.6e-12 45.9 0.0 7.7e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORY52453.1 - 4.6e-09 36.6 0.3 1.1e-08 35.4 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Fungal_trans PF04082.18 ORY52454.1 - 0.027 13.5 0.1 0.048 12.7 0.1 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY52455.1 - 0.00013 22.0 11.0 0.00025 21.1 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY52455.1 - 0.00041 19.5 0.4 0.0023 17.0 0.4 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Cep3 PF16846.5 ORY52455.1 - 0.011 14.3 0.1 0.017 13.7 0.1 1.1 1 0 0 1 1 1 0 Centromere DNA-binding protein complex CBF3 subunit B MBOAT PF03062.19 ORY52456.1 - 3.1e-33 115.6 11.0 6.4e-33 114.5 11.0 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Peptidase_U4 PF03419.13 ORY52456.1 - 6.9 5.9 10.1 0.28 10.4 2.9 2.4 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Zn_clus PF00172.18 ORY52457.1 - 4.3e-15 55.6 19.7 3.5e-08 33.4 5.4 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 ORY52457.1 - 0.035 13.9 0.5 0.035 13.9 0.5 2.8 2 1 0 2 2 2 0 Integrin plexin domain Ssl1 PF04056.14 ORY52458.1 - 3.6e-71 239.0 0.0 5.4e-71 238.4 0.0 1.3 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 ORY52458.1 - 6.6e-14 51.9 17.6 3.2e-13 49.7 8.7 2.5 2 0 0 2 2 2 2 TFIIH C1-like domain VWA_2 PF13519.6 ORY52458.1 - 7.7e-09 36.2 0.0 3.5e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain Tfb4 PF03850.14 ORY52458.1 - 0.00023 20.7 0.2 0.00037 20.1 0.2 1.5 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA PF00092.28 ORY52458.1 - 0.0056 17.0 0.0 0.0089 16.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-HIT PF04438.16 ORY52458.1 - 0.018 14.9 1.7 0.018 14.9 1.7 3.4 4 0 0 4 4 4 0 HIT zinc finger IBR PF01485.21 ORY52458.1 - 6.7 7.0 19.8 1.3 9.4 8.3 2.6 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain Zn_clus PF00172.18 ORY52459.1 - 1e-05 25.5 11.2 1.7e-05 24.9 11.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 ORY52460.1 - 9.5e-16 57.6 27.2 4e-09 36.5 10.9 2.2 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 ORY52461.1 - 9.7e-08 32.0 11.2 1.3e-07 31.6 11.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 ORY52462.1 - 1.4e-05 25.1 9.5 1.4e-05 25.1 9.5 2.8 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain eRF1_2 PF03464.15 ORY52463.1 - 0.015 15.6 0.1 0.017 15.4 0.1 1.1 1 0 0 1 1 1 0 eRF1 domain 2 DUF5355 PF17306.2 ORY52463.1 - 0.094 11.8 0.1 0.11 11.5 0.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5355) Zn_clus PF00172.18 ORY52464.1 - 1.2e-08 35.0 14.4 1.8e-08 34.4 14.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 ORY52465.1 - 1.7e-08 34.5 7.4 2.5e-08 33.9 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 ORY52466.1 - 5.7e-06 26.4 11.7 8.6e-06 25.8 11.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RCC1 PF00415.18 ORY52468.1 - 4.5e-32 110.4 14.9 1.3e-08 35.3 0.0 6.8 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 ORY52468.1 - 6.8e-15 54.4 27.8 4.2e-07 29.6 0.9 5.6 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Chitin_synth_2 PF03142.15 ORY52472.1 - 1.8e-201 670.4 0.0 2.3e-201 670.0 0.0 1.0 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 ORY52472.1 - 2.1e-14 53.9 0.2 4.9e-14 52.7 0.2 1.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY52472.1 - 2.6e-11 43.9 0.0 7.9e-10 39.0 0.0 2.3 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ORY52472.1 - 2e-05 24.1 0.0 0.05 13.1 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 ORY52472.1 - 0.034 14.0 0.0 0.75 9.6 0.0 2.5 3 0 0 3 3 3 0 Glycosyl transferase family 2 JSRP PF15312.6 ORY52473.1 - 1.3 9.0 3.9 1.4 8.9 1.6 2.3 2 1 0 2 2 2 0 Junctional sarcoplasmic reticulum protein KORA PF16509.5 ORY52474.1 - 0.0068 16.7 0.1 0.017 15.4 0.1 1.7 2 0 0 2 2 2 1 TrfB plasmid transcriptional repressor DUF4018 PF13210.6 ORY52474.1 - 0.035 13.9 0.8 0.04 13.7 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4018) Tmpp129 PF10272.9 ORY52474.1 - 0.085 12.2 1.3 0.095 12.0 1.3 1.0 1 0 0 1 1 1 0 Putative transmembrane protein precursor Cullin PF00888.22 ORY52476.1 - 7.5e-122 408.0 0.7 3.8e-111 372.7 0.4 3.0 2 1 0 2 2 2 2 Cullin family DUF1295 PF06966.12 ORY52476.1 - 5.5e-45 153.7 9.7 1e-44 152.8 9.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Cullin_Nedd8 PF10557.9 ORY52476.1 - 1.1e-12 47.8 2.5 2.9e-12 46.4 2.5 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain ICMT PF04140.14 ORY52476.1 - 0.057 13.8 0.0 0.19 12.2 0.0 1.9 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family SecA_SW PF07516.13 ORY52476.1 - 0.2 11.7 1.4 0.98 9.4 0.0 2.5 2 0 0 2 2 2 0 SecA Wing and Scaffold domain DUF1295 PF06966.12 ORY52478.1 - 2e-18 66.8 1.5 2.4e-18 66.5 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 ORY52478.1 - 0.005 17.2 0.5 0.0076 16.6 0.1 1.7 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.17 ORY52478.1 - 0.072 11.8 0.8 0.079 11.7 0.8 1.1 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 ORY52478.1 - 0.078 13.4 3.8 0.99 9.8 0.3 2.4 2 1 0 2 2 2 0 Phospholipid methyltransferase TraL PF07178.11 ORY52478.1 - 1.1 9.7 3.9 0.66 10.5 0.5 2.1 2 1 0 2 2 2 0 TraL protein PhoR PF11808.8 ORY52478.1 - 4 7.9 7.1 6.3 7.3 0.9 2.3 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR DUF1295 PF06966.12 ORY52479.1 - 5.9e-10 39.1 0.5 7.6e-10 38.7 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) TPR_2 PF07719.17 ORY52480.1 - 3.2e-24 83.0 0.6 0.018 15.1 0.0 8.2 8 1 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 ORY52480.1 - 4e-20 70.3 0.0 0.02 15.1 0.0 7.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 ORY52480.1 - 3.6e-17 61.4 4.7 0.038 13.8 0.0 7.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 ORY52480.1 - 6.5e-17 61.6 3.3 0.027 14.7 0.0 6.6 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 ORY52480.1 - 4.6e-15 55.0 0.6 0.0042 17.8 0.4 6.7 3 2 4 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 ORY52480.1 - 3.1e-11 42.8 4.5 0.21 12.0 0.1 7.1 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 ORY52480.1 - 5.3e-10 39.7 1.1 0.061 13.8 1.9 5.1 2 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY52480.1 - 5.3e-08 33.4 1.2 5.8 7.7 0.0 5.5 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 ORY52480.1 - 1.9e-06 27.9 0.0 0.018 15.2 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY52480.1 - 0.00017 21.4 5.6 1.6 8.9 0.0 6.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 ORY52480.1 - 0.00021 21.1 5.0 0.023 14.6 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat NARP1 PF12569.8 ORY52480.1 - 0.00026 20.0 0.7 0.00055 19.0 0.7 1.5 1 1 0 1 1 1 1 NMDA receptor-regulated protein 1 RPN7 PF10602.9 ORY52480.1 - 0.00075 19.3 0.8 0.057 13.1 0.0 2.7 2 2 0 2 2 2 1 26S proteasome subunit RPN7 TPR_15 PF13429.6 ORY52480.1 - 0.0085 15.3 1.8 0.64 9.2 0.6 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY52480.1 - 0.012 15.9 7.7 3.7 7.8 0.3 4.6 2 1 3 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 ORY52480.1 - 0.012 14.6 1.1 0.042 12.8 0.2 2.0 1 1 2 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 ORY52480.1 - 0.023 15.3 5.9 16 6.4 0.3 5.7 7 0 0 7 7 6 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 ORY52481.1 - 1.7e-11 44.3 0.7 1.2e-09 38.2 0.0 2.5 3 0 0 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY52481.1 - 7.1e-06 25.5 0.0 0.00017 21.0 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 FSH1 PF03959.13 ORY52481.1 - 0.0099 15.6 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF2974 PF11187.8 ORY52481.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DS PF01916.17 ORY52482.1 - 1.5e-128 428.1 0.0 1.7e-128 427.9 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase FA_desaturase PF00487.24 ORY52483.1 - 7.6e-14 52.1 27.3 7.6e-14 52.1 27.3 2.0 1 1 1 2 2 2 1 Fatty acid desaturase FA_desaturase PF00487.24 ORY52485.1 - 0.0013 18.6 0.8 0.0017 18.2 0.8 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Peptidase_M48 PF01435.18 ORY52486.1 - 1.4e-36 126.2 0.0 2.5e-36 125.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Amidase02_C PF12123.8 ORY52486.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase LRR_4 PF12799.7 ORY52487.1 - 4.2e-07 30.2 0.0 0.0024 18.3 0.0 2.7 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY52487.1 - 0.0072 16.1 0.0 0.39 10.5 0.0 2.4 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.33 ORY52487.1 - 0.0082 16.5 0.3 17 6.5 0.0 3.6 3 1 0 3 3 3 2 Leucine Rich Repeat ARF7EP_C PF14949.6 ORY52487.1 - 0.058 14.0 1.0 0.076 13.6 1.0 1.2 1 0 0 1 1 1 0 ARF7 effector protein C-terminus LRR_4 PF12799.7 ORY52488.1 - 0.0032 17.8 3.1 0.0062 16.9 1.5 2.4 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY52488.1 - 0.13 12.9 5.3 5.6 7.9 0.2 3.7 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 ORY52488.1 - 1.4 9.2 0.0 1.4 9.2 0.0 3.1 4 0 0 4 4 4 0 Leucine Rich repeat DUF3584 PF12128.8 ORY52489.1 - 0.35 8.3 22.4 0.73 7.3 22.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TCTP PF00838.17 ORY52491.1 - 2.7e-52 177.5 0.2 3e-52 177.3 0.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein AKAP7_NLS PF10469.9 ORY52491.1 - 0.027 14.4 0.0 0.029 14.3 0.0 1.1 1 0 0 1 1 1 0 AKAP7 2'5' RNA ligase-like domain POTRA_TamA_1 PF17243.2 ORY52491.1 - 0.094 12.8 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 POTRA domain TamA domain 1 RhoGAP PF00620.27 ORY52492.1 - 3.9e-10 39.8 0.0 4.5e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain LRR_4 PF12799.7 ORY52493.1 - 1.1e-11 44.7 5.2 2.8e-05 24.4 0.6 3.0 2 1 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY52493.1 - 5.9e-09 35.6 11.7 3.4e-06 26.7 5.8 3.2 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 ORY52493.1 - 6.2e-08 32.1 7.9 0.56 11.0 0.2 5.5 5 0 0 5 5 5 3 Leucine Rich Repeat F-box PF00646.33 ORY52493.1 - 0.00017 21.3 0.0 0.00036 20.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.6 ORY52493.1 - 0.0014 18.5 9.6 1.2 9.4 0.4 4.3 4 0 0 4 4 4 3 Leucine Rich repeat F-box-like PF12937.7 ORY52493.1 - 0.0084 16.0 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like ANF_receptor PF01094.28 ORY52494.1 - 5.7e-16 58.6 0.0 7.6e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region ABC_membrane PF00664.23 ORY52495.1 - 6.6e-52 176.8 30.0 2.5e-25 89.7 11.8 3.2 2 1 1 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 ORY52495.1 - 6.8e-13 49.3 0.0 2.2e-10 41.2 0.0 3.2 2 1 0 2 2 2 2 ABC transporter LRR_9 PF14580.6 ORY52496.1 - 3e-09 36.6 0.0 4.4e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 ORY52496.1 - 4.8e-08 32.6 4.2 9.8e-05 22.0 0.2 1.7 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 ORY52496.1 - 3.2e-06 27.4 0.2 6.1e-06 26.5 0.2 1.5 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) Mpp10 PF04006.12 ORY52496.1 - 0.02 13.4 20.2 0.024 13.1 20.2 1.1 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 ORY52496.1 - 0.025 14.0 25.2 0.03 13.8 25.2 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 ORY52496.1 - 0.12 11.6 25.9 0.15 11.4 25.9 1.1 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 ORY52496.1 - 0.44 9.3 1.4 0.51 9.1 1.4 1.1 1 0 0 1 1 1 0 Presenilin CDC27 PF09507.10 ORY52496.1 - 3.8 6.8 20.4 4.6 6.5 20.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Drc1-Sld2 PF11719.8 ORY52496.1 - 7.6 6.0 14.8 10 5.5 14.8 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein NAD_binding_1 PF00175.21 ORY52497.1 - 1.5e-09 38.4 0.5 4e-07 30.7 0.5 3.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 ORY52497.1 - 6.9e-06 26.3 0.0 1.4e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain ANF_receptor PF01094.28 ORY52498.1 - 7e-11 41.8 0.0 9.6e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY52498.1 - 0.0019 17.9 0.0 0.0026 17.5 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein 7tm_3 PF00003.22 ORY52499.1 - 6.8e-21 75.1 18.7 1e-20 74.5 18.7 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF4181 PF13789.6 ORY52499.1 - 2.4 8.4 8.2 0.82 10.0 0.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) ANF_receptor PF01094.28 ORY52500.1 - 2.6e-16 59.7 0.0 3.8e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY52500.1 - 0.00075 19.2 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein 7tm_3 PF00003.22 ORY52501.1 - 2.9e-14 53.4 17.6 4.3e-14 52.8 17.6 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bax1-I PF01027.20 ORY52501.1 - 0.0027 17.6 14.5 0.0027 17.6 14.5 1.6 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 DUF5367 PF17329.2 ORY52501.1 - 0.018 15.2 3.9 0.018 15.2 3.9 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5367) Ribul_P_3_epim PF00834.19 ORY52501.1 - 0.09 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family BaxI_1 PF12811.7 ORY52501.1 - 0.16 11.5 16.1 0.057 13.0 13.6 1.5 2 0 0 2 2 2 0 Bax inhibitor 1 like DUF3290 PF11694.8 ORY52501.1 - 1.1 9.2 6.9 0.33 10.9 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3290) IKI3 PF04762.12 ORY52502.1 - 1.4e-143 480.1 5.5 1.6e-48 165.5 3.5 4.6 2 2 1 4 4 4 4 IKI3 family ANF_receptor PF01094.28 ORY52503.1 - 0.07 12.2 0.0 0.089 11.9 0.0 1.1 1 0 0 1 1 1 0 Receptor family ligand binding region 7tm_3 PF00003.22 ORY52504.1 - 4.1e-07 30.0 9.9 7.2e-07 29.2 9.9 1.3 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR MtrF PF09472.10 ORY52504.1 - 0.16 11.4 1.3 0.23 10.9 0.1 1.9 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Tctex-1 PF03645.13 ORY52506.1 - 3.1e-24 85.2 0.1 3.9e-24 84.9 0.1 1.1 1 0 0 1 1 1 1 Tctex-1 family FixO PF02433.15 ORY52506.1 - 0.069 12.6 0.1 0.084 12.3 0.1 1.1 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO DUF3574 PF12098.8 ORY52506.1 - 0.074 12.8 0.1 0.18 11.6 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) Microvir_H PF04687.12 ORY52506.1 - 0.11 11.8 0.1 0.13 11.6 0.1 1.1 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) RhoGAP PF00620.27 ORY52507.1 - 0.00029 20.7 0.0 0.00049 19.9 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain TPR_2 PF07719.17 ORY52508.1 - 5.3e-20 69.9 8.0 0.096 12.8 0.0 8.7 8 2 2 10 10 9 5 Tetratricopeptide repeat TPR_9 PF13371.6 ORY52508.1 - 2.7e-19 69.1 0.8 9.1e-06 25.7 0.0 5.1 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 ORY52508.1 - 5.2e-17 60.9 8.9 0.00018 21.2 0.0 8.3 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_14 PF13428.6 ORY52508.1 - 4e-15 55.2 5.0 0.046 14.5 0.6 7.4 3 3 5 8 8 8 4 Tetratricopeptide repeat DnaJ PF00226.31 ORY52508.1 - 2.7e-13 49.8 5.9 3e-13 49.7 3.6 2.3 1 1 1 2 2 2 1 DnaJ domain TPR_19 PF14559.6 ORY52508.1 - 6.8e-12 45.7 8.3 0.00075 20.0 0.1 6.3 3 3 3 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORY52508.1 - 9.8e-10 38.0 1.0 0.031 14.0 0.0 6.2 6 1 1 7 7 7 2 TPR repeat TPR_16 PF13432.6 ORY52508.1 - 5.5e-09 36.5 0.1 0.0045 17.6 0.5 4.3 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 ORY52508.1 - 6.9e-09 35.2 8.3 12 6.4 0.1 8.4 8 1 1 9 9 8 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 ORY52508.1 - 1.9e-05 24.6 0.6 0.27 11.3 0.0 4.5 4 1 1 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 ORY52508.1 - 2.7e-05 24.2 1.8 0.36 11.3 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat PknG_TPR PF16918.5 ORY52508.1 - 0.0001 21.2 0.2 0.0088 14.8 0.0 2.5 2 0 0 2 2 2 1 Protein kinase G tetratricopeptide repeat TPR_6 PF13174.6 ORY52508.1 - 0.00075 20.0 16.4 0.76 10.5 0.1 7.9 8 1 0 8 8 6 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 ORY52508.1 - 0.0046 16.6 1.2 0.75 9.4 0.0 3.8 2 1 1 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_20 PF14561.6 ORY52508.1 - 0.063 13.6 10.8 2 8.8 0.2 4.8 2 1 2 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.14 ORY52508.1 - 0.097 12.1 4.5 0.9 8.9 0.1 3.2 2 2 0 3 3 3 0 Coatomer epsilon subunit ArnB_C PF18677.1 ORY52508.1 - 0.098 12.8 1.0 1 9.5 0.3 3.1 3 0 0 3 3 2 0 Archaellum regulatory network B, C-terminal domain Rotamase PF00639.21 ORY52508.1 - 0.26 12.3 2.6 2.2 9.3 2.2 2.7 2 0 0 2 2 2 0 PPIC-type PPIASE domain SesA PF17107.5 ORY52508.1 - 0.33 11.1 2.5 1.5 9.0 0.1 3.1 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases BTAD PF03704.17 ORY52508.1 - 0.47 10.9 4.4 4.5 7.7 0.2 3.5 2 1 1 3 3 3 0 Bacterial transcriptional activator domain RPT PF13446.6 ORY52508.1 - 0.52 10.3 2.5 3.9 7.5 0.1 3.2 3 0 0 3 3 3 0 A repeated domain in UCH-protein HemY_N PF07219.13 ORY52508.1 - 8.1 6.7 8.7 7.1 6.9 0.5 3.8 3 2 2 5 5 4 0 HemY protein N-terminus DEAD PF00270.29 ORY52509.1 - 9.9e-49 165.5 0.0 1.9e-48 164.5 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY52509.1 - 2.9e-27 95.2 0.1 4.2e-25 88.3 0.6 2.9 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY52509.1 - 9.7e-06 25.7 0.0 1.6e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Keratin_2_head PF16208.5 ORY52509.1 - 0.013 15.6 29.2 0.026 14.7 29.2 1.5 1 0 0 1 1 1 0 Keratin type II head CMS1 PF14617.6 ORY52509.1 - 0.11 11.8 0.2 0.33 10.3 0.0 1.9 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Ribosomal_S7 PF00177.21 ORY52510.1 - 3.3e-35 120.9 1.7 4.2e-35 120.6 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Mannosyl_trans3 PF11051.8 ORY52511.1 - 2.1e-38 132.2 0.1 2.5e-37 128.7 0.1 2.0 1 1 0 1 1 1 1 Mannosyltransferase putative Ion_trans PF00520.31 ORY52512.1 - 1e-17 64.2 11.4 1.2e-17 64.0 11.4 1.0 1 0 0 1 1 1 1 Ion transport protein SpoIISA_toxin PF14171.6 ORY52512.1 - 0.0093 15.7 0.1 0.013 15.2 0.1 1.2 1 0 0 1 1 1 1 Toxin SpoIISA, type II toxin-antitoxin system TssO PF17561.2 ORY52512.1 - 0.057 13.5 1.5 0.99 9.5 0.1 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssO DUF4834 PF16118.5 ORY52512.1 - 0.16 13.0 1.5 2.1 9.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) PalH PF08733.10 ORY52512.1 - 0.19 10.7 3.2 0.072 12.1 0.6 1.7 1 1 1 2 2 2 0 PalH/RIM21 NGP1NT PF08153.12 ORY52513.1 - 8.8e-53 177.9 1.4 2.5e-52 176.4 1.4 1.8 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 ORY52513.1 - 9.1e-15 54.7 0.1 5.9e-11 42.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY52513.1 - 0.00049 20.1 0.2 0.0015 18.5 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 ORY52513.1 - 0.0013 18.2 0.1 0.0058 16.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 ORY52513.1 - 0.0058 16.1 0.1 0.066 12.7 0.0 2.5 3 0 0 3 3 3 1 ADP-ribosylation factor family Dynamin_N PF00350.23 ORY52513.1 - 0.02 14.9 0.2 0.78 9.8 0.0 3.1 3 0 0 3 3 3 0 Dynamin family LRR_8 PF13855.6 ORY52514.1 - 3e-21 74.9 26.5 1.6e-08 34.1 4.0 3.3 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY52514.1 - 8.7e-21 73.7 14.7 3.2e-07 30.5 0.6 5.0 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY52514.1 - 4.9e-15 53.8 11.3 0.0064 16.9 0.2 7.0 7 0 0 7 7 7 5 Leucine Rich Repeat FNIP PF05725.12 ORY52514.1 - 0.00057 20.0 0.7 0.26 11.5 0.7 3.9 1 1 0 1 1 1 1 FNIP Repeat LRR_6 PF13516.6 ORY52514.1 - 0.0091 16.0 15.8 0.39 10.9 0.3 5.8 6 0 0 6 6 6 2 Leucine Rich repeat CIA30 PF08547.12 ORY52515.1 - 3.3e-24 85.7 0.1 6.8e-24 84.7 0.1 1.5 1 1 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Guanylate_kin PF00625.21 ORY52518.1 - 3.9e-52 176.6 0.0 4.4e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 ORY52518.1 - 1.1e-05 25.9 0.0 1.5e-05 25.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 ORY52518.1 - 1.4e-05 25.4 0.0 0.00018 21.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 ORY52518.1 - 0.00085 19.3 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 ORY52518.1 - 0.0012 19.0 0.0 0.002 18.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.6 ORY52518.1 - 0.0022 18.1 0.0 0.0084 16.2 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 ORY52518.1 - 0.0028 17.8 0.0 0.0048 17.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 ORY52518.1 - 0.0032 18.0 0.1 0.004 17.7 0.1 1.6 1 1 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 ORY52518.1 - 0.0061 16.8 0.0 0.04 14.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 ORY52518.1 - 0.0061 17.1 0.0 0.0092 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 ORY52518.1 - 0.0071 16.7 0.0 0.014 15.8 0.0 1.7 1 1 0 1 1 1 1 RNA helicase NACHT PF05729.12 ORY52518.1 - 0.0078 16.1 0.0 0.026 14.4 0.0 1.9 2 0 0 2 2 2 1 NACHT domain Rad17 PF03215.15 ORY52518.1 - 0.013 15.5 0.0 0.019 14.9 0.0 1.3 1 1 0 1 1 1 0 Rad17 P-loop domain AAA_29 PF13555.6 ORY52518.1 - 0.014 15.2 0.1 0.028 14.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 ORY52518.1 - 0.018 14.8 0.0 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 ORY52518.1 - 0.024 14.6 0.0 0.085 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 ORY52518.1 - 0.029 14.3 0.0 0.054 13.4 0.0 1.7 1 1 0 1 1 1 0 NTPase cobW PF02492.19 ORY52518.1 - 0.04 13.5 0.0 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 ORY52518.1 - 0.053 13.4 0.0 0.071 13.0 0.0 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Sugarporin_N PF11471.8 ORY52518.1 - 0.059 13.3 0.3 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension AAA_23 PF13476.6 ORY52518.1 - 0.089 13.3 0.3 0.75 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 ORY52518.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA PF00004.29 ORY52518.1 - 0.12 12.8 0.0 0.18 12.3 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) dNK PF01712.19 ORY52518.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.5 2 0 0 2 2 2 0 Deoxynucleoside kinase Roc PF08477.13 ORY52518.1 - 0.13 12.5 0.0 0.31 11.3 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 ORY52518.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain CCDC144C PF14915.6 ORY52519.1 - 0.003 16.7 15.7 0.0037 16.4 15.7 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region Lectin_N PF03954.14 ORY52519.1 - 0.0081 15.9 5.8 0.0081 15.9 5.8 2.1 1 1 1 2 2 2 1 Hepatic lectin, N-terminal domain HAUS-augmin3 PF14932.6 ORY52519.1 - 0.035 13.7 11.1 0.043 13.4 11.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 UPF0242 PF06785.11 ORY52519.1 - 0.036 14.2 17.6 0.023 14.8 16.2 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus HIP1_clath_bdg PF16515.5 ORY52519.1 - 0.11 13.1 18.5 0.36 11.5 2.5 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FAM76 PF16046.5 ORY52519.1 - 0.11 11.8 13.0 0.13 11.6 13.0 1.1 1 0 0 1 1 1 0 FAM76 protein Baculo_PEP_C PF04513.12 ORY52519.1 - 0.16 12.0 9.1 0.044 13.8 5.0 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 ORY52519.1 - 0.2 11.0 4.4 0.24 10.7 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 ORY52519.1 - 0.22 11.9 13.7 0.3 11.5 13.7 1.2 1 0 0 1 1 1 0 Fez1 TolA_bind_tri PF16331.5 ORY52519.1 - 0.23 11.6 16.1 0.15 12.2 12.4 2.3 2 1 1 3 3 3 0 TolA binding protein trimerisation Csm1_N PF18504.1 ORY52519.1 - 0.48 10.8 19.5 0.15 12.4 2.0 3.3 1 1 2 3 3 3 0 Csm1 N-terminal domain Tropomyosin_1 PF12718.7 ORY52519.1 - 1.1 9.4 19.9 0.97 9.6 15.3 2.0 1 1 1 2 2 2 0 Tropomyosin like COG2 PF06148.11 ORY52519.1 - 1.2 9.2 12.1 1.2 9.2 4.1 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DHR10 PF18595.1 ORY52519.1 - 1.4 9.0 18.9 0.23 11.5 9.6 2.5 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain TEX13 PF15186.6 ORY52519.1 - 1.7 8.3 12.8 0.47 10.1 4.7 2.2 1 1 1 2 2 2 0 Testis-expressed sequence 13 protein family zf-C4H2 PF10146.9 ORY52519.1 - 3.8 7.7 16.6 5.7 7.2 16.6 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein GIT_CC PF16559.5 ORY52519.1 - 5.3 7.0 15.4 0.14 12.0 5.3 2.5 1 1 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DUF2203 PF09969.9 ORY52519.1 - 6.6 7.5 8.3 3.3 8.4 4.6 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) 2_5_RNA_ligase2 PF13563.6 ORY52521.1 - 3.1e-30 105.1 0.2 3.7e-30 104.8 0.2 1.1 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 ORY52521.1 - 4.5e-08 33.2 0.0 0.0071 16.5 0.0 2.1 2 0 0 2 2 2 2 LigT like Phosphoesterase 2OG-FeII_Oxy_2 PF13532.6 ORY52522.1 - 9.4e-21 74.9 0.0 2.3e-20 73.6 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 ORY52522.1 - 0.00083 19.4 2.2 0.0018 18.3 2.2 1.6 1 0 0 1 1 1 1 GRF zinc finger Gasdermin_C PF17708.1 ORY52522.1 - 0.13 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Gasdermin PUB domain SelR PF01641.18 ORY52523.1 - 1.8e-48 163.6 1.9 4e-39 133.4 0.7 2.0 1 1 1 2 2 2 2 SelR domain Yippee-Mis18 PF03226.14 ORY52523.1 - 0.023 14.9 1.4 0.28 11.4 1.4 2.1 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.7 ORY52523.1 - 0.071 13.1 1.4 4.5 7.4 0.4 2.3 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 ORY52523.1 - 0.13 12.0 1.8 1.3 8.8 0.2 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf-CCHC PF00098.23 ORY52524.1 - 0.02 15.0 2.5 0.02 15.0 2.5 1.8 2 0 0 2 2 2 0 Zinc knuckle Nup192 PF11894.8 ORY52525.1 - 1.1e-169 566.6 11.1 4.1e-115 385.6 4.3 3.6 2 1 0 3 3 3 2 Nuclear pore complex scaffold, nucleoporins 186/192/205 BLOC1_2 PF10046.9 ORY52525.1 - 0.16 12.3 5.7 11 6.4 0.1 4.4 5 0 0 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 BUD22 PF09073.10 ORY52525.1 - 0.93 8.8 18.5 1.7 7.9 18.5 1.3 1 0 0 1 1 1 0 BUD22 zf-HIT PF04438.16 ORY52526.1 - 3.8e-08 33.1 10.4 7.9e-08 32.0 10.4 1.6 1 0 0 1 1 1 1 HIT zinc finger Thymopoietin PF08198.11 ORY52526.1 - 0.065 12.8 0.1 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Thymopoietin protein RNA_pol_Rpb8 PF03870.15 ORY52527.1 - 1.3e-23 83.7 0.3 1.5e-23 83.5 0.3 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RRN3 PF05327.11 ORY52528.1 - 1.3e-142 476.2 13.1 1.6e-142 475.9 13.1 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 SMG1 PF15785.5 ORY52528.1 - 0.00035 19.1 2.8 0.0035 15.8 0.2 2.3 2 0 0 2 2 2 2 Serine/threonine-protein kinase smg-1 PPR_long PF17177.4 ORY52528.1 - 0.044 13.1 0.3 0.11 11.8 0.1 1.8 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP TMEM138 PF14935.6 ORY52530.1 - 2.7e-20 73.2 6.2 4.4e-20 72.5 6.2 1.3 1 0 0 1 1 1 1 Transmembrane protein 138 Zw10 PF06248.13 ORY52531.1 - 2.6e-50 171.5 0.7 3.4e-50 171.2 0.7 1.0 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 CBM_21 PF03370.13 ORY52532.1 - 2.8e-10 40.4 0.0 5e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 ORY52532.1 - 6.9e-06 26.6 0.0 1.8e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) EB PF01683.18 ORY52533.1 - 0.017 15.4 12.2 0.54 10.6 0.8 3.2 2 1 1 3 3 3 0 EB module Opy2 PF09463.10 ORY52533.1 - 7.6 6.9 19.3 19 5.7 1.9 3.8 3 1 0 3 3 3 0 Opy2 protein GSHPx PF00255.19 ORY52535.1 - 2e-38 130.3 0.1 2.6e-38 129.9 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 ORY52535.1 - 0.012 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.10 ORY52535.1 - 0.074 12.8 0.0 0.21 11.3 0.0 1.8 1 1 0 1 1 1 0 Redoxin UDPGT PF00201.18 ORY52536.1 - 3.7e-05 22.7 0.0 6.3e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.20 ORY52536.1 - 0.00018 21.5 0.0 0.00048 20.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Aldolase_II PF00596.21 ORY52537.1 - 7.2e-44 149.9 0.0 8.6e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain ATP-synt_F PF01990.17 ORY52538.1 - 2.3e-32 111.1 0.1 2.7e-32 110.9 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit PIN_8 PF18476.1 ORY52538.1 - 0.075 12.9 0.0 0.086 12.7 0.0 1.1 1 0 0 1 1 1 0 PIN like domain DXP_synthase_N PF13292.6 ORY52538.1 - 0.13 11.4 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase PAP_assoc PF03828.19 ORY52539.1 - 5e-20 71.5 0.0 9.5e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase DUF4702 PF15774.5 ORY52539.1 - 0.0041 16.1 0.0 0.029 13.3 0.0 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4702) Zn_clus PF00172.18 ORY52541.1 - 1e-05 25.5 13.1 2.1e-05 24.5 13.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY52541.1 - 0.032 13.3 0.1 0.056 12.5 0.1 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain OrfB_Zn_ribbon PF07282.11 ORY52542.1 - 0.035 14.0 0.7 0.075 13.0 0.7 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain PBP PF01161.20 ORY52544.1 - 8e-15 55.3 0.0 1.8e-14 54.2 0.0 1.6 1 1 0 1 1 1 1 Phosphatidylethanolamine-binding protein YhzD PF14120.6 ORY52544.1 - 0.14 12.3 0.0 0.53 10.4 0.0 2.0 2 0 0 2 2 2 0 YhzD-like protein F-box_4 PF15966.5 ORY52545.1 - 0.00034 20.5 0.2 0.00066 19.5 0.2 1.4 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 ORY52545.1 - 0.00058 19.7 0.5 0.00058 19.7 0.5 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY52545.1 - 0.001 18.9 0.5 0.001 18.9 0.5 2.7 3 0 0 3 3 3 1 F-box domain MASE5 PF17178.4 ORY52545.1 - 3.2 7.5 9.5 0.45 10.3 4.7 1.9 2 0 0 2 2 2 0 Membrane-associated sensor Chs7 PF12271.8 ORY52546.1 - 4.7e-103 344.5 14.7 5.4e-103 344.3 14.7 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone VWA_2 PF13519.6 ORY52547.1 - 9.1e-05 23.1 0.0 0.00048 20.7 0.0 2.3 2 1 1 3 3 3 1 von Willebrand factor type A domain DUF1244 PF06844.11 ORY52547.1 - 0.49 10.6 4.5 0.38 11.0 1.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1244) DUF2681 PF10883.8 ORY52547.1 - 4.5 7.8 8.2 0.088 13.2 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) TMEM40 PF15817.5 ORY52548.1 - 0.015 15.0 4.8 1.6 8.5 0.3 2.3 1 1 1 2 2 2 0 Transmembrane protein 40 family Opy2 PF09463.10 ORY52548.1 - 5.7 7.3 16.8 3.9 7.9 2.3 2.7 2 0 0 2 2 2 0 Opy2 protein YcgR PF07317.12 ORY52549.1 - 0.00021 21.1 5.1 53 3.7 0.0 5.5 1 1 2 5 5 5 5 Flagellar regulator YcgR CN_hydrolase PF00795.22 ORY52550.1 - 1.7e-61 207.9 0.0 1.9e-61 207.7 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ATP11 PF06644.11 ORY52551.1 - 4.1e-63 213.7 1.5 4.7e-63 213.5 1.5 1.0 1 0 0 1 1 1 1 ATP11 protein F-box-like PF12937.7 ORY52552.1 - 0.0079 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 ORY52552.1 - 0.016 15.1 1.2 0.048 13.6 0.2 2.3 2 0 0 2 2 2 0 F-box domain SIKE PF05769.11 ORY52554.1 - 0.038 13.9 0.1 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 SIKE family APC_N_CC PF16689.5 ORY52554.1 - 0.084 13.0 0.5 0.22 11.6 0.5 1.6 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain DivIC PF04977.15 ORY52554.1 - 0.16 11.8 2.0 0.24 11.2 0.8 1.9 3 0 0 3 3 3 0 Septum formation initiator HALZ PF02183.18 ORY52554.1 - 0.26 11.5 3.2 0.82 9.9 2.3 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper Guanylate_kin PF00625.21 ORY52555.1 - 7.4e-59 198.5 0.0 1e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 ORY52555.1 - 9.1e-06 26.1 0.1 2.7e-05 24.6 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 ORY52555.1 - 2.2e-05 24.7 0.0 7.4e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 ORY52555.1 - 2.2e-05 25.0 0.0 5.1e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 ORY52555.1 - 4.4e-05 23.5 0.0 0.00023 21.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 ORY52555.1 - 5.6e-05 23.4 0.0 9.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 ORY52555.1 - 0.0001 22.8 0.0 0.00018 22.0 0.0 1.4 1 1 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 ORY52555.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase RNA_helicase PF00910.22 ORY52555.1 - 0.01 16.2 0.0 0.022 15.1 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 ORY52555.1 - 0.013 15.3 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 ORY52555.1 - 0.015 15.2 0.0 0.024 14.6 0.0 1.4 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 ORY52555.1 - 0.024 14.5 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 ORY52555.1 - 0.026 15.0 0.1 0.075 13.5 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T3SS_needle_E PF08988.10 ORY52555.1 - 0.039 14.1 0.5 0.47 10.6 0.1 2.1 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle AAA_30 PF13604.6 ORY52555.1 - 0.044 13.5 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 ORY52555.1 - 0.047 14.1 0.0 0.34 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 ORY52555.1 - 0.053 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 ORY52555.1 - 0.053 13.5 0.0 0.078 13.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ORY52555.1 - 0.072 13.6 0.2 0.1 13.1 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 ORY52555.1 - 0.081 13.2 0.0 0.23 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 ORY52555.1 - 0.085 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 ORY52555.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Rad17 PF03215.15 ORY52555.1 - 0.092 12.7 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_7 PF12775.7 ORY52555.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 ORY52555.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Septin Roc PF08477.13 ORY52555.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Thymidylate_kin PF02223.17 ORY52555.1 - 0.12 12.0 0.0 0.4 10.3 0.0 1.8 1 1 0 1 1 1 0 Thymidylate kinase NTPase_1 PF03266.15 ORY52555.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 NTPase Val_tRNA-synt_C PF10458.9 ORY52555.1 - 0.16 12.3 0.4 0.33 11.3 0.4 1.5 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm dNK PF01712.19 ORY52555.1 - 0.18 11.7 0.0 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase IL7 PF01415.16 ORY52557.1 - 0.056 13.5 0.2 0.16 12.0 0.2 1.8 1 0 0 1 1 1 0 Interleukin 7/9 family FtsK_SpoIIIE PF01580.18 ORY52557.1 - 0.082 12.2 0.2 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family OxoGdeHyase_C PF16870.5 ORY52557.1 - 0.1 12.3 0.3 0.41 10.3 0.2 2.0 2 0 0 2 2 2 0 2-oxoglutarate dehydrogenase C-terminal FA_desaturase PF00487.24 ORY52558.1 - 1.5e-23 83.9 10.8 1.5e-23 83.9 10.8 1.8 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 ORY52558.1 - 5.6e-18 64.2 4.8 1e-17 63.3 4.8 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Alk_phosphatase PF00245.20 ORY52559.1 - 2.5e-50 171.6 0.1 9.7e-50 169.7 0.1 1.9 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 ORY52559.1 - 0.013 14.8 0.1 0.034 13.5 0.0 1.6 2 0 0 2 2 2 0 Metalloenzyme superfamily Ras PF00071.22 ORY52560.1 - 9.7e-20 70.8 0.0 6e-18 65.0 0.0 2.3 2 0 0 2 2 2 1 Ras family Roc PF08477.13 ORY52560.1 - 0.0031 17.7 0.0 0.17 12.1 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 ORY52560.1 - 0.0097 15.5 0.0 0.029 13.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 ORY52560.1 - 0.041 14.3 0.5 0.12 12.8 0.5 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 ORY52560.1 - 0.1 12.3 0.2 0.26 11.0 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 ORY52560.1 - 0.11 12.4 0.2 13 5.7 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 ORY52560.1 - 0.23 11.8 0.9 9.2 6.5 0.2 2.9 2 1 1 3 3 3 0 AAA domain SR-25 PF10500.9 ORY52560.1 - 5.1 6.6 7.5 8.7 5.9 7.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cyt-b5 PF00173.28 ORY52561.1 - 1.8e-25 88.8 0.0 2.2e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MHB PF16525.5 ORY52561.1 - 0.0095 16.2 0.0 0.013 15.7 0.0 1.2 1 0 0 1 1 1 1 Haemophore, haem-binding zf-C2H2_4 PF13894.6 ORY52562.1 - 9.5e-09 35.4 7.6 0.00053 20.6 1.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY52562.1 - 2.9e-07 30.6 18.5 0.0011 19.3 4.2 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY52562.1 - 1.5e-06 28.3 12.8 0.0024 18.2 1.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 ORY52562.1 - 0.00059 19.8 9.0 0.0094 15.9 1.8 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 ORY52562.1 - 0.00096 19.4 4.8 0.0015 18.8 4.8 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 ORY52562.1 - 0.028 14.7 1.5 0.61 10.4 0.2 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-TFIIB PF13453.6 ORY52562.1 - 0.086 12.2 1.3 0.15 11.4 1.3 1.4 1 0 0 1 1 1 0 Transcription factor zinc-finger zf-AN1 PF01428.16 ORY52562.1 - 0.096 12.9 5.2 1.6 8.9 0.2 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger zf-C2HE PF16278.5 ORY52562.1 - 0.12 12.9 8.2 1 9.9 2.0 2.4 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger TRAF6_Z2 PF18048.1 ORY52562.1 - 0.18 11.9 3.7 4.1 7.6 0.8 2.5 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-C2H2_2 PF12756.7 ORY52562.1 - 0.37 11.2 4.5 7.1 7.0 2.5 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn_Tnp_IS1595 PF12760.7 ORY52562.1 - 0.51 10.4 4.8 1.2 9.2 4.8 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain Actin_micro PF17003.5 ORY52562.1 - 3.9 6.6 4.6 58 2.7 4.6 2.0 1 1 0 1 1 1 0 Putative actin-like family Claudin_3 PF06653.11 ORY52563.1 - 0.0037 17.2 2.4 0.0048 16.8 2.4 1.1 1 0 0 1 1 1 1 Tight junction protein, Claudin-like Prominin PF05478.11 ORY52563.1 - 0.011 13.8 0.1 0.012 13.7 0.1 1.1 1 0 0 1 1 1 0 Prominin DUF3283 PF11686.8 ORY52564.1 - 0.069 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3283) CrgA PF06781.12 ORY52564.1 - 2.4 8.3 4.4 0.44 10.6 0.6 1.9 2 1 0 2 2 2 0 Cell division protein CrgA HlyIII PF03006.20 ORY52566.1 - 8.3e-35 120.5 23.2 2.6e-34 118.9 23.2 1.8 1 1 0 1 1 1 1 Haemolysin-III related GWT1 PF06423.12 ORY52567.1 - 0.0081 16.3 4.8 0.71 10.0 0.2 2.4 1 1 1 2 2 2 2 GWT1 YfmQ PF10787.9 ORY52567.1 - 0.017 14.9 0.1 0.032 14.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein from bacillus cereus group DUF1218 PF06749.12 ORY52567.1 - 0.97 10.0 6.3 0.18 12.3 1.1 2.5 2 2 0 2 2 2 0 Protein of unknown function (DUF1218) EF-hand_8 PF13833.6 ORY52568.1 - 0.00032 20.5 0.1 0.00059 19.6 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 ORY52568.1 - 0.025 14.1 0.1 0.045 13.3 0.1 1.4 1 0 0 1 1 1 0 EF hand EF-hand_1 PF00036.32 ORY52568.1 - 0.029 13.9 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 EF hand Pex24p PF06398.11 ORY52568.1 - 0.085 11.8 1.3 0.11 11.5 1.3 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin EF-hand_7 PF13499.6 ORY52568.1 - 0.11 12.9 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair MPC PF03650.13 ORY52570.1 - 7.4e-40 135.5 0.8 8.2e-40 135.4 0.8 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Aldo_ket_red PF00248.21 ORY52571.1 - 2.7e-34 118.7 0.0 6.3e-33 114.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family MoaC PF01967.21 ORY52571.1 - 0.09 12.9 0.1 0.34 11.0 0.0 1.8 2 0 0 2 2 2 0 MoaC family zf-C2H2_4 PF13894.6 ORY52572.1 - 8e-05 23.2 12.6 0.16 12.9 1.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY52572.1 - 0.0012 19.1 0.3 0.0012 19.1 0.3 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 ORY52572.1 - 0.0013 19.1 19.4 0.017 15.5 2.0 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 ORY52572.1 - 0.0032 17.2 2.3 0.0032 17.2 2.3 2.3 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_3rep PF18868.1 ORY52572.1 - 0.31 11.7 2.2 2.3 8.9 1.9 2.3 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_2 PF12756.7 ORY52572.1 - 1.6 9.1 4.8 2.1 8.7 0.5 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) WD40 PF00400.32 ORY52575.1 - 1.8e-11 44.4 6.2 0.0022 18.8 0.1 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat N2227 PF07942.12 ORY52576.1 - 3.3e-103 344.6 0.0 4e-103 344.3 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.12 ORY52576.1 - 0.0076 17.0 0.0 0.039 14.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY52576.1 - 0.086 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Arrestin_N PF00339.29 ORY52577.1 - 0.11 12.6 0.1 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Ribosomal_60s PF00428.19 ORY52577.1 - 0.34 11.5 3.3 1.1 9.9 3.3 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein BAG PF02179.16 ORY52580.1 - 2.5e-14 53.4 1.6 3.2e-14 53.1 0.2 1.8 1 1 1 2 2 2 1 BAG domain ubiquitin PF00240.23 ORY52580.1 - 0.14 11.9 0.4 3.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin family Glyco_hydro_18 PF00704.28 ORY52581.1 - 4.2e-50 171.3 0.4 5.1e-50 171.0 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 ORY52582.1 - 5.2e-41 141.4 0.1 6.3e-41 141.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GST_N_3 PF13417.6 ORY52583.1 - 3e-13 50.0 0.0 5.4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 ORY52583.1 - 6.8e-09 35.9 0.1 2.2e-08 34.3 0.0 1.9 2 1 1 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY52583.1 - 0.0013 18.7 0.9 0.002 18.1 0.9 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 ORY52583.1 - 0.0088 16.4 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_5 PF18485.1 ORY52583.1 - 0.072 13.5 0.0 0.16 12.3 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ThrE PF06738.12 ORY52585.1 - 3.6e-47 160.7 26.8 2.4e-46 158.0 8.2 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 ORY52585.1 - 2.4e-07 31.0 34.3 1.9e-05 24.8 12.2 3.4 3 1 0 3 3 3 2 Threonine/Serine exporter, ThrE Hydrolase_4 PF12146.8 ORY52587.1 - 0.00031 20.1 0.3 0.00062 19.1 0.3 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY52587.1 - 0.0013 19.4 0.0 0.0018 19.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 ORY52587.1 - 0.02 14.8 0.0 0.096 12.5 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 ORY52587.1 - 0.058 12.9 0.4 0.13 11.7 0.2 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family QCR10 PF09796.9 ORY52588.1 - 5.4e-11 42.4 0.1 6.8e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Mon2_C PF16206.5 ORY52589.1 - 1.6e-50 172.1 0.1 4.5e-34 117.7 0.0 3.3 2 1 1 3 3 3 3 C-terminal region of Mon2 protein Sec7_N PF12783.7 ORY52589.1 - 7.4e-35 120.2 2.9 7.4e-35 120.2 2.9 2.1 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 ORY52589.1 - 0.0016 18.1 3.8 0.52 10.0 0.3 3.4 2 1 1 3 3 3 2 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 ORY52589.1 - 0.0035 17.2 0.1 0.013 15.3 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1981) Isochorismatase PF00857.20 ORY52590.1 - 5.8e-21 75.4 0.0 1e-20 74.6 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family Peroxin-3 PF04882.12 ORY52591.1 - 9.2e-61 206.3 3.8 1.4e-21 77.1 0.1 4.7 1 1 2 3 3 3 3 Peroxin-3 IBR PF01485.21 ORY52591.1 - 3.5e-05 23.9 8.1 3.5e-05 23.9 8.1 2.5 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain EHD_N PF16880.5 ORY52591.1 - 3.9e-05 23.5 0.1 0.083 12.8 0.0 2.5 2 0 0 2 2 2 2 N-terminal EH-domain containing protein DUF3090 PF11290.8 ORY52591.1 - 0.16 11.7 0.2 0.16 11.7 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3090) zf-ribbon_3 PF13248.6 ORY52591.1 - 6.9 6.2 14.6 4.3 6.9 0.2 4.1 4 0 0 4 4 4 0 zinc-ribbon domain Ank_2 PF12796.7 ORY52592.1 - 7.8e-14 52.0 1.9 5.9e-07 30.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 ORY52592.1 - 1e-13 50.0 1.1 0.00082 19.7 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 ORY52592.1 - 4.5e-11 42.7 0.3 0.031 14.7 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 ORY52592.1 - 1.5e-08 35.0 0.7 0.0017 18.9 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY52592.1 - 4.2e-06 26.9 1.5 0.32 11.4 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ion_trans PF00520.31 ORY52592.1 - 0.042 13.1 7.2 0.058 12.6 7.2 1.2 1 0 0 1 1 1 0 Ion transport protein Lactamase_B_5 PF14597.6 ORY52594.1 - 0.037 13.5 0.0 0.037 13.5 0.0 1.1 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily SmaI PF17411.2 ORY52594.1 - 0.14 11.3 0.0 1 8.5 0.0 1.9 2 0 0 2 2 2 0 Type II site-specific deoxyribonuclease Vps51 PF08700.11 ORY52596.1 - 1.8e-22 79.2 0.0 5.5e-22 77.6 0.0 1.9 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 ORY52596.1 - 1.5e-13 50.1 3.6 2.6e-13 49.4 3.6 1.3 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.6 ORY52596.1 - 3.4e-12 46.6 1.5 6.2e-12 45.7 1.4 1.6 1 1 0 1 1 1 1 Exocyst complex component Sec5 Vps54_N PF10475.9 ORY52596.1 - 5.3e-07 29.2 1.7 9.6e-06 25.1 0.6 2.3 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 ORY52596.1 - 4e-06 26.9 0.0 1.2e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps53_N PF04100.12 ORY52596.1 - 0.01 14.9 2.1 0.019 13.9 2.1 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal ABC_tran PF00005.27 ORY52597.1 - 2.2e-53 180.5 0.0 3.5e-26 92.4 0.0 2.8 3 0 0 3 3 3 2 ABC transporter ABC2_membrane_3 PF12698.7 ORY52597.1 - 4.3e-33 114.9 48.2 9.3e-20 71.0 16.0 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 ORY52597.1 - 9.4e-13 48.6 7.2 0.00073 19.4 0.1 4.2 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 ORY52597.1 - 7.9e-07 29.7 0.0 0.0083 16.8 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) SMC_N PF02463.19 ORY52597.1 - 6.4e-06 25.8 2.3 0.45 9.9 0.1 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Mg_chelatase PF01078.21 ORY52597.1 - 1.3e-05 24.7 0.5 0.032 13.6 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI YccF PF03733.13 ORY52597.1 - 0.00032 21.3 5.0 0.00032 21.3 5.0 4.9 6 1 1 7 7 2 1 Inner membrane component domain AAA_23 PF13476.6 ORY52597.1 - 0.00038 21.0 2.3 0.42 11.1 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 ORY52597.1 - 0.0065 16.2 2.5 0.22 11.3 0.5 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Rad17 PF03215.15 ORY52597.1 - 0.012 15.6 0.0 0.62 10.0 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 ORY52597.1 - 0.015 15.3 0.9 2.5 8.2 0.2 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY52597.1 - 0.019 14.9 0.2 5.5 6.9 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_15 PF13175.6 ORY52597.1 - 0.044 13.5 4.8 6.4 6.4 0.1 3.1 3 0 0 3 3 3 0 AAA ATPase domain FeoB_N PF02421.18 ORY52597.1 - 0.16 11.5 1.6 4.1 6.9 0.1 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B MukB PF04310.12 ORY52597.1 - 0.25 11.1 1.6 0.41 10.4 0.1 1.9 2 0 0 2 2 2 0 MukB N-terminal SRP54 PF00448.22 ORY52597.1 - 0.67 9.5 1.9 16 5.1 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain OrfB_Zn_ribbon PF07282.11 ORY52599.1 - 0.0019 18.1 0.1 0.0019 18.1 0.1 2.4 2 0 0 2 2 2 1 Putative transposase DNA-binding domain ATPase-cat_bd PF12156.8 ORY52599.1 - 0.062 14.0 0.8 0.23 12.2 0.8 2.0 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase DDE_3 PF13358.6 ORY52603.1 - 6.1e-09 35.8 0.2 7.6e-09 35.5 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_ISAZ013 PF07592.11 ORY52603.1 - 0.059 12.4 0.3 0.08 11.9 0.3 1.4 1 1 1 2 2 2 0 Rhodopirellula transposase DDE domain DOG1 PF14144.6 ORY52603.1 - 0.16 12.2 0.1 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 Seed dormancy control DDE_3 PF13358.6 ORY52604.1 - 8.2e-13 48.3 0.0 9e-13 48.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease CDC73_C PF05179.14 ORY52605.1 - 5.5e-45 152.9 0.4 8.7e-45 152.2 0.4 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 ORY52605.1 - 1.6e-11 44.1 0.0 2.5e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Paf1 complex subunit CDC73 N-terminal Peptidase_M16_C PF05193.21 ORY52607.1 - 2.8e-30 105.7 0.0 5.1e-30 104.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 ORY52607.1 - 8.1e-30 103.8 0.0 1.5e-29 102.9 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Homeodomain PF00046.29 ORY52608.1 - 1.1e-06 28.4 1.2 1.8e-06 27.7 0.3 1.9 2 0 0 2 2 2 1 Homeodomain SWIM PF04434.17 ORY52608.1 - 0.014 15.0 0.5 0.025 14.3 0.5 1.4 1 0 0 1 1 1 0 SWIM zinc finger Homeobox_KN PF05920.11 ORY52608.1 - 0.07 13.0 0.9 0.16 11.9 0.9 1.6 1 0 0 1 1 1 0 Homeobox KN domain DUF2890 PF11081.8 ORY52608.1 - 1.4 9.0 4.6 0.48 10.5 1.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2890) F-box_4 PF15966.5 ORY52609.1 - 0.00031 20.6 0.0 0.0014 18.5 0.0 2.0 2 0 0 2 2 2 1 F-box PEP-utilizers_C PF02896.18 ORY52609.1 - 0.2 10.7 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain Histone PF00125.24 ORY52612.1 - 1.5e-50 171.0 2.1 1.6e-50 170.8 2.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 ORY52612.1 - 3.9e-05 23.9 0.0 6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 ORY52612.1 - 0.00012 22.1 0.0 0.00023 21.2 0.0 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 ORY52612.1 - 0.0042 17.3 0.0 0.0087 16.3 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAF PF15715.5 ORY52612.1 - 0.014 16.0 1.0 0.017 15.7 1.0 1.1 1 0 0 1 1 1 0 PCNA-associated factor histone like domain TFIID-31kDa PF02291.15 ORY52612.1 - 0.041 13.9 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 ORY52612.1 - 0.095 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated F-box_4 PF15966.5 ORY52613.1 - 0.053 13.4 0.1 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 F-box PRANC PF09372.10 ORY52613.1 - 0.09 13.1 0.0 3.2 8.1 0.0 2.7 3 0 0 3 3 3 0 PRANC domain DUF2096 PF09869.9 ORY52613.1 - 0.12 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) F-box-like PF12937.7 ORY52613.1 - 0.13 12.2 1.0 0.68 9.9 0.1 2.5 2 0 0 2 2 2 0 F-box-like SIMPL PF04402.14 ORY52614.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF541) COMPASS-Shg1 PF05205.12 ORY52616.1 - 0.00023 21.8 1.4 0.00056 20.6 0.1 2.4 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 SPP PF06550.11 ORY52617.1 - 0.00026 20.6 3.5 0.00026 20.6 3.5 1.6 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease Spec3 PF15795.5 ORY52617.1 - 0.056 14.0 0.7 0.056 14.0 0.7 2.4 2 1 0 2 2 2 0 Ectodermal ciliogenesis protein DUF4491 PF14898.6 ORY52617.1 - 0.17 12.4 2.6 0.83 10.1 0.7 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4491) ArAE_1 PF06081.11 ORY52617.1 - 0.65 10.1 6.1 0.11 12.7 1.2 2.2 2 0 0 2 2 2 0 Aromatic acid exporter family member 1 7TM_GPCR_Srd PF10317.9 ORY52617.1 - 0.8 8.8 18.3 33 3.6 18.3 2.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd Sas10_Utp3 PF04000.15 ORY52618.1 - 6.5e-20 71.5 2.8 1.9e-19 70.1 2.8 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family SMAP PF15477.6 ORY52618.1 - 0.027 15.4 0.1 0.99 10.4 0.0 2.8 2 0 0 2 2 2 0 Small acidic protein family HMG_box PF00505.19 ORY52619.1 - 5e-22 78.1 1.8 8.1e-22 77.4 1.8 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY52619.1 - 3.9e-11 43.4 2.2 6.4e-11 42.7 2.2 1.3 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 ORY52619.1 - 0.006 16.5 0.1 0.016 15.2 0.0 1.7 2 1 1 3 3 3 1 CHDNT (NUC034) domain YABBY PF04690.13 ORY52619.1 - 0.095 13.3 1.6 0.11 13.1 0.6 1.6 1 1 1 2 2 2 0 YABBY protein Rep_fac-A_C PF08646.10 ORY52620.1 - 1.8e-47 160.8 0.2 1.8e-47 160.8 0.2 2.8 3 0 0 3 3 3 1 Replication factor-A C terminal domain Rep-A_N PF04057.12 ORY52620.1 - 2.1e-20 72.6 0.0 2.8e-19 69.0 0.0 2.4 2 0 0 2 2 2 1 Replication factor-A protein 1, N-terminal domain REPA_OB_2 PF16900.5 ORY52620.1 - 4e-17 61.9 0.0 1.1e-16 60.6 0.0 1.8 1 0 0 1 1 1 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 ORY52620.1 - 2.6e-07 30.5 0.2 8.5e-05 22.5 0.1 3.2 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF4539 PF15072.6 ORY52620.1 - 0.01 15.9 0.0 0.099 12.7 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4539) PAT1 PF09770.9 ORY52620.1 - 0.041 12.2 14.4 0.052 11.8 14.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 ORY52620.1 - 0.22 11.6 2.0 0.33 11.0 2.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 ORY52620.1 - 0.94 9.4 27.2 1.5 8.8 27.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 ORY52620.1 - 4.2 6.0 8.8 6.3 5.5 8.8 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 ORY52620.1 - 5.1 5.7 6.8 6.9 5.2 6.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Glyco_hydro_35 PF01301.19 ORY52621.1 - 5.9e-58 197.0 3.8 1.3e-56 192.5 3.8 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 ORY52621.1 - 2.1e-08 33.9 0.1 6.7e-08 32.3 0.0 1.7 2 0 0 2 2 2 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 ORY52621.1 - 5.5e-05 23.7 0.1 0.28 11.8 0.0 3.3 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain Cellulase PF00150.18 ORY52621.1 - 0.016 14.7 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Sel1 PF08238.12 ORY52622.1 - 9.4e-22 77.0 2.5 4.1e-06 27.3 0.6 3.4 3 0 0 3 3 3 3 Sel1 repeat TPR_6 PF13174.6 ORY52622.1 - 2.5e-05 24.6 0.6 0.94 10.3 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 ORY52622.1 - 0.015 15.6 0.5 1.9 9.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Aldedh PF00171.22 ORY52624.1 - 2.3e-12 46.2 4.8 3e-09 35.9 2.0 2.3 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Rad51 PF08423.11 ORY52625.1 - 2.9e-10 39.8 0.0 4.1e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 ORY52625.1 - 0.0005 19.6 0.0 0.00081 18.9 0.0 1.4 2 0 0 2 2 2 1 recA bacterial DNA recombination protein ATPase PF06745.13 ORY52625.1 - 0.0014 18.0 0.0 0.0051 16.2 0.0 1.8 2 0 0 2 2 2 1 KaiC DUF2492 PF10678.9 ORY52625.1 - 0.11 12.8 0.1 0.35 11.2 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2492) F-box_4 PF15966.5 ORY52626.1 - 0.0063 16.4 0.3 0.016 15.1 0.0 1.8 2 0 0 2 2 2 1 F-box Isochorismatase PF00857.20 ORY52627.1 - 6.4e-21 75.3 0.0 7.5e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family SASP_gamma PF04259.14 ORY52628.1 - 0.13 12.8 1.7 1.1 9.9 0.3 2.2 2 0 0 2 2 2 0 Small, acid-soluble spore protein, gamma-type Ycf70 PF17382.2 ORY52628.1 - 0.2 12.1 0.0 0.33 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized Ycf70-like MadM PF03818.13 ORY52629.1 - 0.67 9.9 6.3 2 8.3 3.1 3.0 2 1 0 2 2 2 0 Malonate/sodium symporter MadM subunit Sm_multidrug_ex PF06695.11 ORY52630.1 - 0.23 12.1 0.3 0.23 12.1 0.3 2.9 1 1 2 3 3 3 0 Putative small multi-drug export protein Aminotran_3 PF00202.21 ORY52631.1 - 1.3e-23 83.3 1.7 3.5e-16 58.9 0.9 3.4 2 1 1 3 3 3 2 Aminotransferase class-III Peptidase_M23 PF01551.22 ORY52631.1 - 5.8e-14 52.1 0.0 1.2e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M23 APH PF01636.23 ORY52631.1 - 3.3e-07 30.5 0.3 6.3e-07 29.6 0.3 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Hydrophobin_2 PF06766.11 ORY52631.1 - 0.15 12.1 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Fungal hydrophobin zf-H2C2_2 PF13465.6 ORY52632.1 - 2.7e-12 46.5 11.3 7.9e-08 32.4 0.4 3.1 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 ORY52632.1 - 1.3e-09 38.0 10.4 7.8e-05 22.9 0.4 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY52632.1 - 1.4e-08 34.8 12.9 0.00024 21.7 0.4 2.4 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY52632.1 - 2.2e-08 34.1 2.6 0.0018 18.5 1.0 2.2 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 ORY52632.1 - 0.00026 21.2 3.6 0.00035 20.8 3.6 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 ORY52632.1 - 0.00037 20.9 4.2 0.068 13.6 1.1 2.1 1 1 1 2 2 2 2 C2HE / C2H2 / C2HC zinc-binding finger zf-MYST PF17772.1 ORY52632.1 - 0.0056 16.3 2.1 1.3 8.7 0.5 2.1 2 0 0 2 2 2 2 MYST family zinc finger domain zf-C2H2_2 PF12756.7 ORY52632.1 - 0.013 15.9 4.9 0.3 11.4 0.8 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 ORY52632.1 - 0.033 14.2 8.6 0.079 13.0 4.5 2.1 1 1 1 2 2 2 0 BED zinc finger zf-FCS PF06467.14 ORY52632.1 - 0.034 14.1 2.0 0.034 14.1 2.0 2.1 1 1 1 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-met PF12874.7 ORY52632.1 - 0.045 14.1 8.5 0.42 11.1 3.0 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf_C2H2_ZHX PF18387.1 ORY52632.1 - 0.047 13.3 6.2 0.57 9.9 4.8 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_6 PF13912.6 ORY52632.1 - 0.72 9.9 12.8 0.9 9.6 5.4 2.6 3 1 0 3 3 3 0 C2H2-type zinc finger zf-MYND PF01753.18 ORY52632.1 - 0.93 9.6 8.5 0.3 11.2 3.1 2.2 1 1 1 2 2 2 0 MYND finger DUF629 PF04780.12 ORY52632.1 - 1.3 7.4 2.9 4.4 5.7 1.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF629) RNase_T PF00929.24 ORY52634.1 - 5e-27 95.4 0.0 5.7e-27 95.3 0.0 1.0 1 0 0 1 1 1 1 Exonuclease HMG_box PF00505.19 ORY52635.1 - 3.7e-10 40.1 0.0 5.8e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY52635.1 - 9.6e-05 22.9 0.0 0.00015 22.2 0.0 1.2 1 0 0 1 1 1 1 HMG-box domain F-box-like PF12937.7 ORY52635.1 - 0.0031 17.4 5.1 0.0053 16.6 3.5 2.2 3 0 0 3 3 3 1 F-box-like Ccdc124 PF06244.12 ORY52635.1 - 0.012 16.1 0.0 0.017 15.7 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 124 /Oxs1 Exo_endo_phos PF03372.23 ORY52637.1 - 0.00043 19.9 0.0 0.00053 19.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_C69 PF03577.15 ORY52640.1 - 0.12 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C69 DAGAT PF03982.13 ORY52641.1 - 8.8e-35 120.0 0.0 8.2e-32 110.3 0.0 2.1 1 1 0 1 1 1 1 Diacylglycerol acyltransferase DAGAT PF03982.13 ORY52642.1 - 4.5e-50 170.2 0.1 6.5e-50 169.7 0.1 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase TFIIE-A_C PF11521.8 ORY52644.1 - 0.01 16.2 0.9 1.8 8.9 0.1 2.2 2 0 0 2 2 2 2 C-terminal general transcription factor TFIIE alpha Zds_C PF08632.10 ORY52647.1 - 0.0014 18.3 0.4 0.003 17.3 0.4 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Zds_C PF08632.10 ORY52649.1 - 0.017 14.9 0.2 0.039 13.7 0.2 1.5 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Zds_C PF08632.10 ORY52650.1 - 0.1 12.4 0.1 0.32 10.8 0.1 1.8 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term Ribosomal_L6 PF00347.23 ORY52651.1 - 1.3e-25 89.8 7.6 3.1e-13 50.2 0.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 SLT_2 PF13406.6 ORY52653.1 - 0.86 8.8 2.5 1.3 8.2 0.3 1.9 2 0 0 2 2 2 0 Transglycosylase SLT domain DUF3319 PF11782.8 ORY52654.1 - 0.029 14.3 0.0 0.57 10.2 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3319) DUF5305 PF17231.2 ORY52654.1 - 0.034 13.5 0.4 0.043 13.2 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Amnionless PF14828.6 ORY52654.1 - 0.07 12.0 0.8 0.076 11.8 0.8 1.1 1 0 0 1 1 1 0 Amnionless Sporozoite_P67 PF05642.11 ORY52655.1 - 0.34 9.0 7.0 0.4 8.7 7.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4641 PF15483.6 ORY52655.1 - 2.5 7.1 5.5 9.3 5.2 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4641) 7tm_1 PF00001.21 ORY52656.1 - 0.033 13.5 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Mtc PF03820.17 ORY52657.1 - 0.19 10.8 0.4 0.22 10.6 0.4 1.1 1 0 0 1 1 1 0 Tricarboxylate carrier 2OG-FeII_Oxy_2 PF13532.6 ORY52661.1 - 9.4e-19 68.4 0.0 6.2e-18 65.7 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_1 PF00561.20 ORY52662.1 - 2.7e-17 63.3 0.1 4.4e-17 62.6 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY52662.1 - 2.7e-15 56.3 0.1 5.8e-15 55.2 0.1 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY52662.1 - 1.3e-13 52.1 0.0 1.8e-13 51.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 ORY52662.1 - 0.00024 20.9 0.0 0.014 15.1 0.1 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family UPF0227 PF05728.12 ORY52662.1 - 0.0013 18.7 0.0 0.0051 16.8 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Chlorophyllase2 PF12740.7 ORY52662.1 - 0.0026 16.7 0.0 0.0094 14.9 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase enzyme Lipase_3 PF01764.25 ORY52662.1 - 0.0038 17.1 0.0 0.0062 16.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) LCAT PF02450.15 ORY52662.1 - 0.18 10.9 0.0 0.24 10.5 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 ORY52663.1 - 3.1e-22 79.5 0.3 5.3e-21 75.4 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY52663.1 - 1.2e-17 64.0 0.1 3.9e-16 59.1 0.1 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY52663.1 - 7.4e-16 59.4 0.5 1e-15 59.0 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 ORY52663.1 - 7.5e-07 28.9 0.0 0.00071 19.2 0.0 3.0 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 ORY52663.1 - 2.3e-05 24.2 0.0 0.27 11.0 0.0 2.8 2 1 0 2 2 2 2 Alpha/beta hydrolase family DUF915 PF06028.11 ORY52663.1 - 3.8e-05 23.2 0.0 0.03 13.6 0.0 3.0 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_4 PF08386.10 ORY52663.1 - 0.00037 20.6 0.0 0.00059 19.9 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Esterase PF00756.20 ORY52663.1 - 0.00081 19.1 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.14 ORY52663.1 - 0.0033 16.2 0.0 0.0064 15.2 0.0 1.4 1 0 0 1 1 1 1 Ndr family Lipase_2 PF01674.18 ORY52663.1 - 0.0081 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) Peptidase_S15 PF02129.18 ORY52663.1 - 0.019 14.6 0.0 0.096 12.3 0.0 1.9 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 ORY52664.1 - 9e-12 45.2 0.1 4.6e-10 39.6 0.1 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY52664.1 - 1.2e-11 44.4 0.1 2.2e-10 40.2 0.1 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY52664.1 - 8.9e-10 39.5 1.1 1.2e-09 39.1 1.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 ORY52664.1 - 0.0021 17.9 0.0 0.062 13.1 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 ORY52664.1 - 0.094 12.3 0.0 0.11 12.1 0.0 1.4 1 1 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 ORY52665.1 - 2.3e-20 73.3 0.1 3.1e-20 72.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY52665.1 - 4.1e-16 59.0 0.0 5.8e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY52665.1 - 1.7e-13 51.7 0.0 2.7e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 ORY52665.1 - 1.2e-05 24.9 0.0 0.031 13.8 0.0 2.9 2 1 1 3 3 3 2 Dienelactone hydrolase family Esterase PF00756.20 ORY52665.1 - 0.016 14.8 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase AXE1 PF05448.12 ORY52665.1 - 0.089 11.4 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF1100 PF06500.11 ORY52665.1 - 0.11 11.3 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Ndr PF03096.14 ORY52665.1 - 0.15 10.7 0.0 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 Ndr family Abhydrolase_1 PF00561.20 ORY52666.1 - 1.3e-23 84.0 0.1 7.4e-18 65.1 0.2 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 ORY52666.1 - 1.1e-17 64.2 0.1 2.7e-17 62.8 0.1 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY52666.1 - 6e-13 49.9 0.4 7.6e-13 49.6 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 ORY52666.1 - 0.00022 21.0 0.0 0.18 11.6 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.18 ORY52666.1 - 0.0096 15.5 0.0 0.092 12.3 0.0 2.1 1 1 0 1 1 1 1 Dienelactone hydrolase family Thioesterase PF00975.20 ORY52666.1 - 0.018 15.2 0.0 0.037 14.1 0.1 1.5 2 0 0 2 2 2 0 Thioesterase domain Ndr PF03096.14 ORY52666.1 - 0.027 13.2 0.0 0.044 12.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family UPF0227 PF05728.12 ORY52666.1 - 0.044 13.7 0.0 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) FSH1 PF03959.13 ORY52666.1 - 0.14 11.8 0.0 1 9.0 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) D-ser_dehydrat PF14031.6 ORY52666.1 - 0.15 12.7 0.0 0.34 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative serine dehydratase domain DUF676 PF05057.14 ORY52666.1 - 0.18 11.3 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) NOA36 PF06524.12 ORY52667.1 - 0.29 10.4 9.5 0.64 9.3 9.5 1.5 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 ORY52667.1 - 0.61 10.1 6.6 1.8 8.6 6.6 1.7 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.13 ORY52667.1 - 1.4 8.7 7.7 3.2 7.6 7.7 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.10 ORY52667.1 - 4.5 7.7 17.4 13 6.2 17.4 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PYST-C1 PF09690.10 ORY52667.1 - 9.2 6.1 8.2 33 4.3 8.2 1.9 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) ThrE PF06738.12 ORY52668.1 - 2.7e-43 148.1 22.0 5e-27 94.8 6.1 3.2 3 0 0 3 3 3 3 Putative threonine/serine exporter ThrE_2 PF12821.7 ORY52668.1 - 5.1e-13 49.3 28.2 5.7e-13 49.1 13.3 2.7 2 1 0 2 2 2 2 Threonine/Serine exporter, ThrE Transcrip_reg PF01709.20 ORY52668.1 - 0.0071 15.8 0.6 0.015 14.7 0.6 1.5 1 0 0 1 1 1 1 Transcriptional regulator OAF PF14941.6 ORY52668.1 - 0.013 15.0 0.3 0.019 14.4 0.3 1.2 1 0 0 1 1 1 0 Transcriptional regulator, Out at first Laminin_G_3 PF13385.6 ORY52669.1 - 3e-08 33.9 0.0 5.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily F-box PF00646.33 ORY52669.1 - 0.00016 21.4 0.1 0.0003 20.6 0.1 1.5 1 0 0 1 1 1 1 F-box domain Laminin_G_2 PF02210.24 ORY52669.1 - 0.00049 20.7 0.1 0.00081 20.0 0.1 1.3 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.23 ORY52669.1 - 0.0012 19.1 0.0 0.0019 18.4 0.0 1.3 1 0 0 1 1 1 1 Laminin G domain F-box-like PF12937.7 ORY52669.1 - 0.015 15.2 0.1 0.033 14.1 0.1 1.6 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 ORY52669.1 - 0.06 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 F-box DNA_pol_phi PF04931.13 ORY52669.1 - 8 4.4 7.5 10 4.1 7.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi FAD_binding_3 PF01494.19 ORY52670.1 - 3.7e-06 26.4 0.6 8.4e-06 25.3 0.6 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 ORY52670.1 - 1e-05 24.9 2.1 0.016 14.4 0.1 2.8 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY52670.1 - 7.4e-05 21.6 0.2 0.044 12.5 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 ORY52670.1 - 0.00039 20.1 0.1 0.1 12.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 ORY52670.1 - 0.0033 17.4 0.3 2.4 8.1 0.1 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding MCRA PF06100.11 ORY52670.1 - 0.004 16.0 0.0 0.0066 15.3 0.0 1.3 1 0 0 1 1 1 1 MCRA family NAD_binding_8 PF13450.6 ORY52670.1 - 0.0073 16.5 0.0 0.024 14.8 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 ORY52670.1 - 0.016 15.7 0.2 0.15 12.6 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 ORY52670.1 - 0.02 14.0 2.9 0.15 11.1 0.3 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 ORY52670.1 - 0.037 12.9 0.2 1.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 ORY52670.1 - 0.045 13.0 0.0 0.26 10.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 ORY52670.1 - 0.14 11.4 0.5 0.21 10.9 0.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HA2 PF04408.23 ORY52671.1 - 1.1e-13 51.4 2.1 4.5e-13 49.4 2.0 2.2 1 1 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 ORY52671.1 - 2.5e-10 40.6 0.0 6.9e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 ORY52671.1 - 1.2e-08 35.2 0.0 2.8e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Syntaphilin PF15290.6 ORY52672.1 - 2.4e-05 24.2 0.3 2.9e-05 23.9 0.3 1.1 1 0 0 1 1 1 1 Golgi-localised syntaxin-1-binding clamp SAICAR_synt PF01259.18 ORY52672.1 - 0.00017 21.3 0.1 0.00022 20.9 0.1 1.1 1 0 0 1 1 1 1 SAICAR synthetase TEX13 PF15186.6 ORY52672.1 - 0.0064 16.2 0.7 0.0084 15.8 0.7 1.1 1 0 0 1 1 1 1 Testis-expressed sequence 13 protein family BRX_N PF13713.6 ORY52672.1 - 0.011 15.5 0.2 0.04 13.7 0.2 2.1 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain IFT20 PF14931.6 ORY52672.1 - 0.031 14.4 2.9 0.045 13.9 2.9 1.2 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 PAPS_reduct PF01507.19 ORY52673.1 - 5.3e-22 78.7 0.0 7.1e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family NIR_SIR PF01077.22 ORY52674.1 - 2.5e-28 98.6 0.8 2.6e-21 75.8 0.5 3.3 2 1 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain Flavodoxin_1 PF00258.25 ORY52674.1 - 5.5e-28 98.0 0.0 1e-27 97.1 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NIR_SIR_ferr PF03460.17 ORY52674.1 - 1.1e-16 60.5 0.0 9.3e-16 57.4 0.0 2.3 2 0 0 2 2 2 1 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_5 PF12724.7 ORY52674.1 - 0.067 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Flavodoxin domain DUF2514 PF10721.9 ORY52678.1 - 0.039 14.0 2.9 0.059 13.4 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Lebercilin PF15619.6 ORY52678.1 - 0.053 13.2 1.7 0.082 12.6 1.7 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Golgin_A5 PF09787.9 ORY52678.1 - 0.11 12.0 1.9 0.13 11.7 1.9 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 PIN_4 PF13638.6 ORY52679.1 - 6.4e-20 71.8 0.0 1.3e-19 70.8 0.0 1.5 1 0 0 1 1 1 1 PIN domain VHS PF00790.19 ORY52680.1 - 4.1e-30 104.5 2.0 4.1e-30 104.5 0.4 1.8 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.28 ORY52680.1 - 6.8e-13 48.0 0.1 1.4e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY52680.1 - 8.9e-10 38.3 0.2 1.8e-09 37.3 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 ORY52680.1 - 1e-08 34.7 0.2 2e-08 33.8 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 ORY52680.1 - 1.7e-05 25.1 1.7 3.7e-05 24.0 0.8 2.1 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 ORY52680.1 - 0.014 15.3 5.4 0.039 13.9 5.4 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif Hrs_helical PF12210.8 ORY52680.1 - 0.074 13.6 0.5 0.2 12.2 0.5 1.7 1 0 0 1 1 1 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Hormone_4 PF00220.17 ORY52680.1 - 0.25 11.4 1.1 0.51 10.4 1.1 1.5 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain G-patch PF01585.23 ORY52681.1 - 1.9e-08 34.0 1.3 6.5e-08 32.4 1.3 2.0 1 0 0 1 1 1 1 G-patch domain Ribosomal_L28 PF00830.19 ORY52682.1 - 0.0071 16.5 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L28 family Pkinase PF00069.25 ORY52683.1 - 6.4e-29 101.1 0.0 2.4e-28 99.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY52683.1 - 3.5e-07 29.8 0.0 7.2e-07 28.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY52683.1 - 0.047 13.0 0.1 0.077 12.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-actin_cap_A PF01267.17 ORY52684.1 - 2e-53 181.6 0.1 4.4e-53 180.4 0.1 1.5 1 1 0 1 1 1 1 F-actin capping protein alpha subunit GP40 PF11025.8 ORY52684.1 - 0.054 13.3 0.1 0.083 12.6 0.1 1.3 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium CSTF2_hinge PF14327.6 ORY52684.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 AAA_12 PF13087.6 ORY52685.1 - 0.047 13.3 1.5 0.086 12.5 1.3 1.7 1 1 0 1 1 1 0 AAA domain MFS_1 PF07690.16 ORY52686.1 - 4.5e-47 160.7 57.5 1.2e-46 159.3 57.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY52686.1 - 6.4e-15 54.6 31.6 8.3e-15 54.2 31.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY52686.1 - 4.8e-09 35.6 12.0 4.8e-09 35.6 12.0 3.0 2 2 1 3 3 3 1 Sugar (and other) transporter DUF2015 PF09435.10 ORY52687.1 - 1.8e-21 76.1 0.0 2.3e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Exo_endo_phos PF03372.23 ORY52690.1 - 3.9e-11 42.9 0.0 8.5e-11 41.8 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family adh_short PF00106.25 ORY52691.1 - 6.2e-25 87.8 0.0 3.1e-20 72.5 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY52691.1 - 9.7e-15 54.7 0.0 2.5e-13 50.1 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_7 PF13241.6 ORY52691.1 - 0.014 15.9 0.0 0.03 14.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding KR PF08659.10 ORY52691.1 - 0.043 13.7 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 KR domain DUF1776 PF08643.10 ORY52691.1 - 0.092 12.1 0.3 0.19 11.0 0.2 1.6 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 ORY52691.1 - 0.14 11.6 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GPI-anchored PF10342.9 ORY52692.1 - 0.00029 21.6 0.2 0.00051 20.7 0.2 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RRM_1 PF00076.22 ORY52693.1 - 3.1e-21 75.0 0.0 2.1e-11 43.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY52693.1 - 8.7e-06 25.5 0.1 0.018 14.9 0.1 2.5 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_3 PF08777.11 ORY52693.1 - 0.029 14.4 0.0 4.3 7.4 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif Peptidase_C48 PF02902.19 ORY52694.1 - 0.0097 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain FAD_binding_1 PF00667.20 ORY52696.1 - 3e-32 112.0 0.1 4.6e-32 111.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 ORY52696.1 - 5e-28 98.1 0.0 1.7e-27 96.4 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 ORY52696.1 - 5.7e-12 46.3 0.0 1.3e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain OTU PF02338.19 ORY52696.1 - 0.04 14.4 0.0 0.08 13.4 0.0 1.5 1 0 0 1 1 1 0 OTU-like cysteine protease Glyco_hydro_18 PF00704.28 ORY52697.1 - 6e-59 200.3 1.3 6.8e-59 200.1 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 ORY52698.1 - 1.5e-62 212.1 1.1 1.7e-62 211.9 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 2-Hacid_dh_C PF02826.19 ORY52699.1 - 2.5e-51 173.6 0.0 4e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 ORY52699.1 - 6.1e-34 116.6 0.0 7.8e-34 116.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 ORY52699.1 - 3e-06 27.5 0.1 7.6e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 ORY52699.1 - 0.069 13.0 0.8 0.9 9.4 0.1 2.5 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 ORY52699.1 - 0.071 12.7 0.3 1 8.9 0.1 2.6 2 1 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain XdhC_C PF13478.6 ORY52699.1 - 0.092 13.3 0.0 0.24 11.9 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain Transp_cyt_pur PF02133.15 ORY52700.1 - 4e-33 114.8 41.7 5.7e-33 114.3 41.7 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NYAP_N PF15439.6 ORY52701.1 - 0.15 11.2 0.1 0.21 10.8 0.1 1.1 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter NRBF2 PF08961.10 ORY52702.1 - 0.0028 17.3 1.3 0.0028 17.3 1.3 2.0 2 0 0 2 2 2 1 Nuclear receptor-binding factor 2, autophagy regulator PRKG1_interact PF15898.5 ORY52702.1 - 0.062 14.2 9.6 0.13 13.1 9.6 1.5 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Seadorna_VP6 PF07407.11 ORY52702.1 - 0.18 10.7 1.7 0.26 10.2 1.7 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein CENP-H PF05837.12 ORY52702.1 - 3.8 8.0 11.3 1.3 9.5 4.4 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) YabA PF06156.13 ORY52702.1 - 4.7 7.9 8.6 1.2 9.8 4.7 1.9 1 1 1 2 2 2 0 Initiation control protein YabA Pkinase PF00069.25 ORY52703.1 - 9.7e-63 212.0 0.0 1.1e-62 211.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY52703.1 - 2e-48 164.9 0.0 2.5e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY52703.1 - 1.1e-07 31.0 0.0 1.6e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY52703.1 - 2.5e-05 23.7 0.0 3.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 ORY52703.1 - 0.02 14.5 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 ORY52703.1 - 0.035 14.0 0.0 0.062 13.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family ART PF01129.18 ORY52703.1 - 0.077 12.3 0.0 0.16 11.3 0.0 1.4 2 0 0 2 2 2 0 NAD:arginine ADP-ribosyltransferase Seadorna_VP7 PF07387.11 ORY52703.1 - 0.13 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 WD40 PF00400.32 ORY52704.1 - 5.6e-26 90.3 27.6 1e-05 26.1 1.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat NLE PF08154.12 ORY52704.1 - 1.7e-17 63.7 0.2 2.8e-17 63.0 0.2 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain ANAPC4_WD40 PF12894.7 ORY52704.1 - 1.3e-05 25.4 3.9 2.2 8.7 0.0 4.8 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY52704.1 - 0.001 17.8 8.1 0.32 9.6 1.0 4.0 1 1 1 3 3 3 2 Nucleoporin Nup120/160 MFS_1 PF07690.16 ORY52705.1 - 9.1e-43 146.5 36.2 9.1e-43 146.5 36.2 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY52705.1 - 1.8e-09 36.6 5.7 1.8e-09 36.6 5.7 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY52705.1 - 1.1e-08 34.4 12.7 1.1e-08 34.4 12.7 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 ORY52705.1 - 0.13 10.7 11.9 0.19 10.1 11.4 1.6 1 1 0 1 1 1 0 Transmembrane secretion effector OATP PF03137.20 ORY52705.1 - 4.7 5.4 9.5 1.1 7.5 5.5 1.8 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family UPF0147 PF03685.13 ORY52841.1 - 0.21 11.7 0.0 1.7 8.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) zf-C2H2 PF00096.26 ORY52843.1 - 5.4e-20 70.7 21.3 1.2e-05 25.5 1.3 4.4 4 1 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY52843.1 - 1.3e-15 56.7 17.3 0.003 18.2 0.7 4.3 4 0 0 4 4 4 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY52843.1 - 3.3e-15 55.7 30.2 2.4e-07 30.9 1.8 4.9 5 1 0 5 5 5 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY52843.1 - 3.9e-15 55.7 18.1 1.3e-05 25.4 0.8 4.5 4 1 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 ORY52843.1 - 7.3e-14 51.4 17.4 0.00026 20.9 1.0 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.7 ORY52843.1 - 2.4e-13 50.0 14.5 4.7e-05 23.6 0.9 4.3 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 ORY52843.1 - 1.1e-05 25.7 15.4 0.12 12.8 0.1 3.7 2 1 2 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.12 ORY52843.1 - 3.3e-05 24.1 14.3 0.042 14.2 0.3 3.5 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding Zn-ribbon_8 PF09723.10 ORY52843.1 - 0.00088 19.3 11.2 1.8 8.7 0.4 4.2 4 0 0 4 4 4 1 Zinc ribbon domain DUF2256 PF10013.9 ORY52843.1 - 0.001 19.2 4.2 2.9 8.1 0.2 3.6 3 0 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_3rep PF18868.1 ORY52843.1 - 0.0019 18.9 9.6 0.37 11.5 0.2 3.3 2 1 1 3 3 3 2 Zinc finger C2H2-type, 3 repeats DUF3785 PF12653.7 ORY52843.1 - 0.011 15.8 3.4 0.019 15.1 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3785) zf-BED PF02892.15 ORY52843.1 - 0.012 15.6 14.9 0.18 11.9 3.3 4.1 2 1 2 4 4 4 0 BED zinc finger zf-C2H2_9 PF16293.5 ORY52843.1 - 0.017 15.0 7.8 0.025 14.4 0.1 3.5 2 1 2 4 4 4 0 C2H2 type zinc-finger (1 copy) HNH_5 PF14279.6 ORY52843.1 - 0.029 14.2 9.9 2.8 7.9 0.1 3.6 4 0 0 4 4 3 0 HNH endonuclease zf-C2H2_8 PF15909.5 ORY52843.1 - 0.03 14.6 2.1 0.03 14.6 2.1 2.3 2 1 1 3 3 2 0 C2H2-type zinc ribbon zf_UBZ PF18439.1 ORY52843.1 - 0.031 13.9 10.6 2.9 7.6 0.1 4.0 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger PyrI_C PF02748.15 ORY52843.1 - 0.053 13.4 0.8 0.053 13.4 0.8 3.8 3 1 1 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zinc_ribbon_15 PF17032.5 ORY52843.1 - 0.078 13.7 13.0 0.34 11.7 2.3 2.2 1 1 1 2 2 2 0 zinc-ribbon family Prok-RING_1 PF14446.6 ORY52843.1 - 0.079 12.9 10.4 3.2 7.7 0.2 4.2 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 zinc-ribbons_6 PF07191.12 ORY52843.1 - 0.093 12.7 14.7 11 6.1 3.5 3.9 1 1 2 3 3 3 0 zinc-ribbons zf-CHCC PF10276.9 ORY52843.1 - 0.26 11.4 0.3 0.26 11.4 0.3 3.0 3 1 0 3 3 2 0 Zinc-finger domain zf-nanos PF05741.13 ORY52843.1 - 0.36 11.1 11.4 25 5.2 3.8 4.0 3 1 0 3 3 3 0 Nanos RNA binding domain Vps39_2 PF10367.9 ORY52843.1 - 0.51 10.8 6.9 15 6.1 0.2 3.3 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 2 zf-MYST PF17772.1 ORY52843.1 - 0.84 9.3 16.2 0.21 11.2 2.8 3.7 3 1 1 4 4 4 0 MYST family zinc finger domain C1_4 PF07975.12 ORY52843.1 - 1.1 9.5 15.3 2.6 8.3 4.2 3.5 1 1 3 4 4 4 0 TFIIH C1-like domain Actin_micro PF17003.5 ORY52843.1 - 1.2 8.3 15.6 1.1 8.4 0.2 3.5 2 1 1 3 3 3 0 Putative actin-like family zf-C2HE PF16278.5 ORY52843.1 - 1.4 9.4 14.9 6.1 7.4 0.1 3.9 1 1 2 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger C1_2 PF03107.16 ORY52843.1 - 1.6 9.1 20.8 11 6.4 0.8 4.2 2 1 1 3 3 3 0 C1 domain DUF2225 PF09986.9 ORY52843.1 - 2.2 7.9 13.5 2.8 7.6 3.8 3.1 3 1 1 4 4 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zf_ZIC PF18366.1 ORY52843.1 - 4.2 7.6 8.7 18 5.6 0.5 3.4 2 1 1 3 3 3 0 Zic proteins zinc finger domain DUF2318 PF10080.9 ORY52843.1 - 4.9 7.3 10.6 0.76 9.9 4.0 2.7 1 1 2 3 3 3 0 Predicted membrane protein (DUF2318) LIM PF00412.22 ORY52843.1 - 6.2 7.1 16.7 3.9 7.8 7.0 3.3 2 1 2 4 4 4 0 LIM domain zf-C2H2 PF00096.26 ORY52844.1 - 1.3e-38 129.3 86.9 0.00059 20.1 2.0 14.2 14 0 0 14 14 14 13 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY52844.1 - 1.8e-29 99.8 88.1 4.1e-05 24.1 1.7 14.3 13 1 1 14 14 14 13 C2H2-type zinc finger zf-H2C2_2 PF13465.6 ORY52844.1 - 9e-16 57.5 89.3 0.00059 20.2 0.6 13.7 15 0 0 15 15 15 7 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY52844.1 - 7.1e-15 54.6 69.1 0.0031 17.5 2.1 12.6 12 0 0 12 12 12 7 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY52844.1 - 6.3e-10 39.2 48.5 4.8e-05 23.6 4.7 7.5 1 1 6 8 8 8 4 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 ORY52844.1 - 3.4e-08 33.6 68.7 0.15 12.3 3.0 13.0 13 1 1 14 14 13 7 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY52844.1 - 0.022 15.2 64.6 1.3 9.5 0.6 12.0 14 0 0 14 14 14 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.10 ORY52844.1 - 0.077 13.1 61.2 0.14 12.3 2.1 8.7 8 1 0 8 8 8 0 Zinc ribbon domain zf-C2H2_3rep PF18868.1 ORY52844.1 - 4.3 8.0 45.8 2.8 8.6 0.7 6.9 1 1 4 6 6 6 0 Zinc finger C2H2-type, 3 repeats zinc_ribbon_15 PF17032.5 ORY52844.1 - 7.4 7.4 55.9 2.2 9.1 4.4 7.4 2 2 5 7 7 7 0 zinc-ribbon family zf-C2H2_2 PF12756.7 ORY52844.1 - 7.4 7.0 71.7 3.4 8.1 0.2 10.8 2 2 7 9 9 8 0 C2H2 type zinc-finger (2 copies) zf-B_box PF00643.24 ORY52845.1 - 3.9e-07 30.1 9.4 3.9e-07 30.1 9.4 3.0 2 0 0 2 2 2 1 B-box zinc finger zf-C3HC4_2 PF13923.6 ORY52845.1 - 0.00022 21.0 14.6 0.00022 21.0 14.6 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 ORY52845.1 - 0.0003 21.1 14.1 0.0003 21.1 14.1 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORY52845.1 - 0.00062 19.6 10.9 0.00062 19.6 10.9 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) LMP PF04778.12 ORY52845.1 - 0.0035 17.3 3.8 0.0072 16.2 3.8 1.5 1 0 0 1 1 1 1 LMP repeated region U-box PF04564.15 ORY52845.1 - 0.014 15.6 0.0 0.064 13.4 0.0 2.2 1 0 0 1 1 1 0 U-box domain MATH PF00917.26 ORY52845.1 - 0.049 13.8 1.4 0.27 11.4 0.0 2.8 3 1 0 3 3 3 0 MATH domain Exonuc_VII_L PF02601.15 ORY52845.1 - 0.076 12.6 3.5 0.16 11.5 3.5 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Nbl1_Borealin_N PF10444.9 ORY52845.1 - 0.24 11.1 1.4 0.57 9.9 0.3 2.2 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal DZR PF12773.7 ORY52845.1 - 1 9.4 19.4 3.1 7.9 2.0 3.4 3 0 0 3 3 3 0 Double zinc ribbon APG6_N PF17675.1 ORY52845.1 - 6.1 7.4 9.7 2.5 8.6 6.5 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region DSBA PF01323.20 ORY52846.1 - 2.3e-22 79.7 0.0 2.9e-21 76.2 0.0 2.1 1 1 0 1 1 1 1 DSBA-like thioredoxin domain TRAM_LAG1_CLN8 PF03798.16 ORY52849.1 - 1.3e-05 25.0 9.0 0.0012 18.7 2.1 2.3 2 0 0 2 2 2 2 TLC domain UL2 PF08196.11 ORY52849.1 - 0.15 12.0 1.6 0.76 9.8 0.4 2.4 2 0 0 2 2 2 0 UL2 protein zf-AN1 PF01428.16 ORY52850.1 - 9.2e-12 44.9 5.1 1.5e-11 44.2 5.1 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger IBR PF01485.21 ORY52850.1 - 0.13 12.5 6.8 0.27 11.5 6.7 1.6 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain RasGAP PF00616.19 ORY52851.1 - 2.3e-22 79.7 0.1 2e-11 44.0 0.0 2.6 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 ORY52851.1 - 3.9e-16 59.5 0.2 1.1e-15 58.0 0.2 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 ORY52851.1 - 3e-06 27.0 0.2 8.3e-06 25.6 0.2 1.8 1 0 0 1 1 1 1 CRAL/TRIO domain HEAT PF02985.22 ORY52851.1 - 0.025 14.8 0.0 2.9 8.4 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat SopA PF13981.6 ORY52851.1 - 0.038 14.4 0.0 0.14 12.6 0.0 2.0 1 0 0 1 1 1 0 SopA-like central domain AFG1_ATPase PF03969.16 ORY52852.1 - 1.1e-43 149.6 0.0 1.2e-42 146.2 0.0 2.4 2 1 0 2 2 2 1 AFG1-like ATPase AAA_22 PF13401.6 ORY52852.1 - 2.1e-06 28.1 0.0 5.9e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 ORY52852.1 - 0.0013 18.3 0.0 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 ORY52852.1 - 0.0031 17.9 0.2 0.12 12.8 0.2 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 ORY52852.1 - 0.032 14.2 0.0 0.17 11.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 ORY52852.1 - 0.035 13.8 0.0 0.087 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 ORY52852.1 - 0.049 14.1 0.0 0.084 13.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 ORY52852.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain ArfA PF03889.13 ORY52853.1 - 2.3e-05 23.8 0.5 1.2e+02 2.2 0.0 6.5 7 0 0 7 7 7 0 Alternative ribosome-rescue factor A XRN1_DBM PF18245.1 ORY52853.1 - 2.4e-05 24.1 0.1 1.5e+02 2.5 0.0 6.3 1 1 6 7 7 7 0 5-3 exonuclease XRN1 DCP1-binding motif Lamprin PF06403.11 ORY52853.1 - 0.056 13.4 5.2 8.5 6.3 0.8 2.7 1 1 2 3 3 3 0 Lamprin 7tm_7 PF08395.12 ORY52854.1 - 0.0002 20.7 0.4 0.32 10.1 0.2 2.0 2 0 0 2 2 2 2 7tm Chemosensory receptor 7tm_1 PF00001.21 ORY52854.1 - 0.0018 17.7 0.3 0.003 16.9 0.3 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Pho88 PF10032.9 ORY52854.1 - 0.06 12.6 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphate transport (Pho88) Frag1 PF10277.9 ORY52854.1 - 0.24 10.9 7.8 0.039 13.5 2.4 1.9 2 0 0 2 2 2 0 Frag1/DRAM/Sfk1 family polyprenyl_synt PF00348.17 ORY52855.1 - 3.2e-94 314.7 0.0 4.3e-94 314.3 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase Rhomboid PF01694.22 ORY52857.1 - 1.4e-23 83.6 13.6 2e-23 83.0 13.6 1.2 1 0 0 1 1 1 1 Rhomboid family Calsarcin PF05556.11 ORY52858.1 - 0.071 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-binding protein (Calsarcin) DUF295 PF03478.18 ORY52859.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF295) FMN_red PF03358.15 ORY52862.1 - 1.2e-09 38.2 0.0 1.9e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 ORY52862.1 - 0.00013 21.8 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 ORY52862.1 - 0.0014 18.8 0.1 0.0028 17.9 0.1 1.4 1 1 0 1 1 1 1 Flavodoxin Aminotran_1_2 PF00155.21 ORY52863.1 - 5.9e-35 121.1 0.0 7.8e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 ORY52863.1 - 0.037 12.6 0.0 0.071 11.6 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RHD3 PF05879.12 ORY52864.1 - 2.7e-197 657.4 0.4 5e-197 656.5 0.4 1.4 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 ORY52864.1 - 2.7e-08 33.4 2.4 4.8e-08 32.6 0.5 2.1 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 ORY52864.1 - 1.2e-05 25.3 0.1 2.9e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 ORY52864.1 - 1.8e-05 24.8 0.0 3.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin family AAA_28 PF13521.6 ORY52864.1 - 0.0017 18.6 0.0 0.0057 16.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 ORY52864.1 - 0.0047 17.1 0.1 0.014 15.6 0.1 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORY52864.1 - 0.0086 15.7 0.2 0.019 14.5 0.2 1.5 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.18 ORY52864.1 - 0.017 14.6 0.2 0.032 13.8 0.2 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.18 ORY52864.1 - 0.031 13.6 0.1 0.052 12.8 0.1 1.3 1 0 0 1 1 1 0 Septin Prefoldin_2 PF01920.20 ORY52865.1 - 0.018 15.0 1.4 0.081 12.9 1.4 1.9 1 1 0 1 1 1 0 Prefoldin subunit DUF3484 PF11983.8 ORY52865.1 - 0.073 14.2 0.8 0.073 14.2 0.8 2.0 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch Peptidase_S9_N PF02897.15 ORY52866.1 - 5.5e-85 285.6 4.0 6.8e-85 285.4 4.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 ORY52866.1 - 1.3e-56 191.4 0.0 3.1e-56 190.2 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF5071 PF16804.5 ORY52866.1 - 0.025 14.9 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5071) DSBA PF01323.20 ORY52867.1 - 2.8e-31 108.8 0.0 3.2e-31 108.6 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain His_biosynth PF00977.21 ORY52868.1 - 7.3e-33 113.9 0.0 1e-32 113.5 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein TPIP1 PF15338.6 ORY52868.1 - 0.03 14.4 0.0 0.049 13.7 0.0 1.3 1 0 0 1 1 1 0 p53-regulated apoptosis-inducing protein 1 Thioredoxin PF00085.20 ORY52869.1 - 1.8e-30 105.0 2.6 1.1e-17 63.9 0.1 2.9 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 ORY52869.1 - 1.3e-07 31.8 0.1 0.0022 17.9 0.0 3.0 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 ORY52869.1 - 1.2e-06 28.8 1.8 0.028 14.7 0.0 4.5 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.6 ORY52869.1 - 0.0023 18.3 2.0 0.49 10.9 0.0 3.7 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 ORY52869.1 - 0.0048 16.9 0.3 0.069 13.2 0.1 2.4 2 0 0 2 2 2 1 Thioredoxin domain Redoxin PF08534.10 ORY52869.1 - 0.0092 15.7 0.5 0.085 12.6 0.0 2.3 2 0 0 2 2 2 1 Redoxin Thioredoxin_7 PF13899.6 ORY52869.1 - 0.042 14.0 0.8 9.5 6.5 0.0 3.5 3 0 0 3 3 3 0 Thioredoxin-like Dak2 PF02734.17 ORY52869.1 - 0.16 11.8 0.6 0.4 10.6 0.0 1.9 2 0 0 2 2 2 0 DAK2 domain OST3_OST6 PF04756.13 ORY52869.1 - 0.36 10.1 2.1 3.5 6.9 0.1 3.0 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family AIP3 PF03915.13 ORY52870.1 - 1.8e-13 50.4 6.2 1.8e-13 50.4 6.2 1.6 2 0 0 2 2 2 1 Actin interacting protein 3 CREPT PF16566.5 ORY52870.1 - 0.45 10.7 6.2 0.17 12.0 1.9 2.6 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Syntaxin_2 PF14523.6 ORY52870.1 - 1.6 9.1 6.7 6.3 7.2 0.9 3.0 2 0 0 2 2 2 0 Syntaxin-like protein SAM_2 PF07647.17 ORY52871.1 - 1.6e-12 47.4 0.1 3.6e-12 46.2 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 ORY52871.1 - 1.1e-11 44.9 0.1 2.1e-11 44.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Arrestin_N PF00339.29 ORY52871.1 - 1.5e-06 28.3 0.4 1.2e-05 25.4 0.1 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 ORY52871.1 - 0.01 16.3 0.7 3.9 7.9 0.1 2.7 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain SAM_PNT PF02198.16 ORY52871.1 - 0.023 14.7 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain SAM_Ste50p PF09235.10 ORY52871.1 - 0.031 14.5 0.1 0.059 13.6 0.1 1.5 1 0 0 1 1 1 0 Ste50p, sterile alpha motif Peptidase_S9_N PF02897.15 ORY52873.1 - 2e-83 280.5 1.6 2.6e-83 280.2 1.6 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 ORY52873.1 - 1.6e-54 184.6 0.0 5.2e-54 182.9 0.0 1.9 1 0 0 1 1 1 1 Prolyl oligopeptidase family AceK PF06315.11 ORY52873.1 - 0.055 12.0 0.1 0.084 11.3 0.1 1.2 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) S1-P1_nuclease PF02265.16 ORY52874.1 - 6.1e-44 150.7 0.0 7.8e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease LPMO_10 PF03067.15 ORY52875.1 - 0.029 15.0 0.0 0.065 13.9 0.0 1.6 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading LPMO_10 PF03067.15 ORY52876.1 - 0.00047 20.9 0.2 0.0008 20.1 0.2 1.5 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Abhydrolase_2 PF02230.16 ORY52877.1 - 9.8e-63 211.8 0.0 1.2e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 ORY52877.1 - 9.2e-07 28.7 0.0 1.2e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 ORY52877.1 - 2.7e-06 26.8 0.3 0.009 15.3 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY52877.1 - 4.6e-05 24.1 0.0 0.00038 21.1 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 ORY52877.1 - 0.00011 21.8 0.1 0.00085 18.9 0.0 2.1 1 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 ORY52877.1 - 0.00016 21.5 0.1 0.0016 18.1 0.1 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 ORY52877.1 - 0.0043 16.9 0.1 0.49 10.2 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Lipase_3 PF01764.25 ORY52877.1 - 0.047 13.6 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PseudoU_synth_1 PF01416.20 ORY52879.1 - 4.3e-24 85.1 0.0 1.4e-23 83.4 0.0 1.9 2 0 0 2 2 2 1 tRNA pseudouridine synthase PBP1_TM PF14812.6 ORY52879.1 - 1.7 9.1 5.4 0.29 11.5 1.5 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal B12D PF06522.11 ORY52880.1 - 0.05 13.4 1.0 0.28 11.0 1.0 2.0 1 1 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit B12D PF06522.11 ORY52881.1 - 0.0008 19.2 0.0 0.00095 18.9 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF3579 PF12112.8 ORY52882.1 - 0.16 12.6 0.0 0.21 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3579) B12D PF06522.11 ORY52883.1 - 0.00073 19.3 0.0 0.0009 19.0 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit FMN_red PF03358.15 ORY52884.1 - 1.2e-05 25.1 0.0 2.4e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 ORY52884.1 - 3.8e-05 23.9 0.1 5.8e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.17 ORY52884.1 - 0.0049 16.6 0.0 0.0064 16.2 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold MAPEG PF01124.18 ORY52885.1 - 1.7e-13 50.6 0.4 2.5e-13 50.1 0.4 1.3 1 1 0 1 1 1 1 MAPEG family DUF456 PF04306.13 ORY52885.1 - 0.24 11.7 10.0 0.064 13.5 7.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF456) PEPCK_ATP PF01293.20 ORY52886.1 - 5.5e-205 681.4 0.0 6.2e-205 681.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase DUF202 PF02656.15 ORY52887.1 - 2.8 8.5 0.0 2.8 8.5 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF202) LRR_8 PF13855.6 ORY52888.1 - 1.7e-08 34.1 14.1 0.00062 19.5 1.8 4.4 3 1 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 ORY52888.1 - 5.7e-05 23.4 18.8 0.095 13.2 3.4 4.9 2 2 1 4 4 4 4 Leucine Rich repeats (2 copies) F-box-like PF12937.7 ORY52888.1 - 0.0055 16.6 0.0 0.022 14.7 0.0 2.1 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 ORY52888.1 - 0.015 15.7 21.0 0.15 12.7 0.3 6.7 8 0 0 8 8 8 0 Leucine Rich Repeat F-box PF00646.33 ORY52888.1 - 0.021 14.7 0.0 0.056 13.3 0.0 1.8 1 0 0 1 1 1 0 F-box domain Tyrosinase PF00264.20 ORY52890.1 - 4.7e-30 105.5 4.3 1.1e-29 104.4 4.3 1.6 1 0 0 1 1 1 1 Common central domain of tyrosinase OmdA PF13376.6 ORY52890.1 - 0.14 12.2 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Tyrosinase PF00264.20 ORY52891.1 - 2.6e-33 116.2 7.6 2.6e-33 116.2 7.6 1.7 2 0 0 2 2 2 1 Common central domain of tyrosinase PAX PF00292.18 ORY52892.1 - 0.00011 22.1 0.0 0.00014 21.8 0.0 1.1 1 0 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.6 ORY52892.1 - 0.0051 17.4 0.5 0.072 13.7 0.1 2.1 1 1 1 2 2 2 1 Homeodomain-like domain HTH_33 PF13592.6 ORY52892.1 - 0.047 13.3 0.0 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn helix HTH_29 PF13551.6 ORY52892.1 - 0.061 13.4 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix Peptidase_S9_N PF02897.15 ORY52895.1 - 3.6e-82 276.4 2.1 4.5e-82 276.1 2.1 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 ORY52895.1 - 1.3e-54 185.0 0.0 5.8e-54 182.8 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family AceK PF06315.11 ORY52895.1 - 0.054 12.0 0.1 0.084 11.3 0.1 1.2 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) zf-met2 PF12907.7 ORY52896.1 - 7.8e-17 61.1 0.3 1.2e-16 60.5 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 ORY52896.1 - 0.00034 21.4 9.5 0.00034 21.4 9.5 1.6 2 0 0 2 2 2 1 4F5 protein family zf-H2C2_2 PF13465.6 ORY52896.1 - 0.0086 16.5 0.2 6.2 7.4 0.0 2.2 2 0 0 2 2 2 2 Zinc-finger double domain zinc_ribbon_4 PF13717.6 ORY52896.1 - 0.031 14.2 0.1 0.061 13.3 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-Di19 PF05605.12 ORY52896.1 - 0.036 14.4 1.8 0.85 10.0 2.1 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-LSD1 PF06943.12 ORY52896.1 - 0.061 13.2 0.1 0.085 12.7 0.1 1.2 1 0 0 1 1 1 0 LSD1 zinc finger Raffinose_syn PF05691.12 ORY52897.1 - 3.6e-50 170.6 3.9 1e-35 122.8 0.0 3.2 2 1 1 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 Glyco_hydro_31 PF01055.26 ORY52897.1 - 2e-07 30.6 0.5 3.3e-07 29.9 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase PF02065.18 ORY52897.1 - 0.0026 16.8 0.4 0.0043 16.1 0.4 1.3 1 0 0 1 1 1 1 Melibiase Melibiase_2 PF16499.5 ORY52897.1 - 0.069 12.3 0.1 0.24 10.6 0.0 1.8 2 0 0 2 2 2 0 Alpha galactosidase A SQS_PSY PF00494.19 ORY52898.1 - 1.3e-42 146.1 0.0 2.1e-42 145.4 0.0 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF4111 PF13427.6 ORY52898.1 - 0.051 13.7 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4111) Cation_ATPase_C PF00689.21 ORY52899.1 - 7e-48 162.7 2.4 7e-48 162.7 2.4 2.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 ORY52899.1 - 1.6e-36 125.5 2.5 1.6e-36 125.5 2.5 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 ORY52899.1 - 5.7e-18 66.0 3.0 2e-15 57.7 3.0 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 ORY52899.1 - 2.9e-17 62.5 0.0 8.6e-17 61.0 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 ORY52899.1 - 4.3e-06 26.3 0.0 1.8e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 ORY52899.1 - 0.00073 19.3 1.1 0.0011 18.8 0.2 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2642 PF10842.8 ORY52899.1 - 0.024 14.5 0.1 0.38 10.6 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) DUF588 PF04535.12 ORY52899.1 - 0.82 9.4 4.7 0.37 10.6 1.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF588) S1-P1_nuclease PF02265.16 ORY52900.1 - 3.3e-45 154.9 0.0 4.1e-45 154.6 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease TPT PF03151.16 ORY52901.1 - 6.1e-25 88.1 12.9 7.6e-25 87.8 12.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 ORY52901.1 - 3.1e-05 23.3 18.2 3.9e-05 23.0 18.2 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 ORY52901.1 - 0.021 15.0 26.3 0.06 13.5 15.5 2.4 2 0 0 2 2 2 0 EamA-like transporter family COX8 PF02285.15 ORY52901.1 - 0.21 11.5 1.0 0.53 10.2 0.2 2.1 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII CorC_HlyC PF03471.17 ORY52901.1 - 0.22 11.6 0.2 0.38 10.8 0.2 1.3 1 0 0 1 1 1 0 Transporter associated domain Dynamitin PF04912.14 ORY52902.1 - 2.4e-29 102.9 4.3 2.1e-17 63.6 0.7 2.4 2 1 0 2 2 2 2 Dynamitin p450 PF00067.22 ORY52903.1 - 1.4e-46 159.2 0.1 2.9e-46 158.2 0.1 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ORY52904.1 - 6e-62 209.9 0.0 7.3e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EcoRII-N PF09217.10 ORY52904.1 - 0.05 13.4 0.2 0.32 10.7 0.1 2.0 2 0 0 2 2 2 0 Restriction endonuclease EcoRII, N-terminal TnsD PF15978.5 ORY52904.1 - 0.17 10.9 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 Tn7-like transposition protein D p450 PF00067.22 ORY52905.1 - 1.5e-52 178.9 0.1 3.2e-52 177.8 0.1 1.4 1 1 1 2 2 2 1 Cytochrome P450 adh_short PF00106.25 ORY52906.1 - 2.9e-29 101.9 0.0 4.5e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY52906.1 - 1.6e-26 93.3 0.0 2.9e-26 92.5 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY52906.1 - 7.9e-05 22.6 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 KR domain p450 PF00067.22 ORY52907.1 - 3.1e-63 214.1 0.0 3.8e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.13 ORY52909.1 - 5.9e-19 68.8 0.0 7.9e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 ORY52909.1 - 1.2e-15 57.3 0.3 3.3e-15 55.9 0.0 1.8 2 1 0 2 2 2 1 Steryl acetyl hydrolase Asn_synthase PF00733.21 ORY52910.1 - 1.9e-14 54.1 0.2 1.1e-06 28.5 0.1 3.4 2 1 0 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 ORY52910.1 - 0.00016 21.6 0.0 0.00051 20.0 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ORY52910.1 - 0.002 18.3 0.0 0.0088 16.2 0.0 2.0 3 0 0 3 3 3 1 Glutamine amidotransferase domain DUF89 PF01937.19 ORY52910.1 - 0.049 12.6 0.4 0.66 8.9 0.3 2.2 1 1 0 1 1 1 0 Protein of unknown function DUF89 Porin_3 PF01459.22 ORY52911.1 - 6.9e-47 160.2 0.0 3.8e-30 105.3 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic porin F-box PF00646.33 ORY52912.1 - 9.8e-07 28.5 0.4 2.3e-06 27.3 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 ORY52912.1 - 0.00011 22.0 0.1 0.00019 21.2 0.1 1.4 1 0 0 1 1 1 1 F-box-like Lipase_3 PF01764.25 ORY52913.1 - 3.8e-22 78.7 0.0 7.1e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 ORY52913.1 - 0.031 14.9 0.0 0.07 13.7 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Chitin_synth_1 PF01644.17 ORY52914.1 - 1e-72 243.5 0.1 1.6e-72 242.8 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ORY52914.1 - 5.3e-26 90.4 0.0 1.2e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ORY52914.1 - 2.7e-23 82.4 11.8 5.1e-19 68.3 0.0 2.9 2 1 1 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ORY52914.1 - 5.7e-10 39.4 0.2 5.7e-10 39.4 0.2 2.9 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY52914.1 - 0.041 13.8 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Glycosyltransferase like family 2 VirB3 PF05101.13 ORY52914.1 - 4.3 7.6 7.9 8 6.8 6.5 2.3 1 1 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Chitin_synth_1 PF01644.17 ORY52915.1 - 7.5e-63 211.4 0.1 1.4e-62 210.5 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 ORY52915.1 - 2.7e-23 81.7 0.0 5.9e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 ORY52915.1 - 1.8e-21 76.4 0.3 3.4e-17 62.3 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 ORY52915.1 - 2.9e-07 30.6 5.9 1.4e-06 28.4 5.9 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 IMS PF00817.20 ORY52916.1 - 1.2e-27 96.7 0.0 9.5e-27 93.8 0.0 2.1 2 0 0 2 2 2 1 impB/mucB/samB family DUF2616 PF11077.8 ORY52916.1 - 0.089 12.5 1.5 0.14 11.8 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) IMS_C PF11799.8 ORY52917.1 - 7e-14 52.5 0.1 1.1e-13 51.9 0.1 1.2 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Acyltransferase PF01553.21 ORY52918.1 - 5.1e-20 71.5 0.0 9.2e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Sgf11 PF08209.11 ORY52919.1 - 1.3e-10 40.6 0.4 1.3e-10 40.6 0.4 2.0 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-CpG_bind_C PF12269.8 ORY52919.1 - 0.023 14.5 0.5 0.033 14.0 0.5 1.3 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain zf-LYAR PF08790.11 ORY52919.1 - 0.054 13.4 0.5 0.11 12.4 0.5 1.6 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger FTP PF07504.13 ORY52920.1 - 2.8e-07 30.2 0.4 5e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 Fungalysin/Thermolysin Propeptide Motif Pkinase PF00069.25 ORY52921.1 - 3.8e-55 187.1 0.0 6.4e-55 186.3 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY52921.1 - 5e-21 75.2 0.0 7e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY52921.1 - 0.0024 17.2 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY52921.1 - 0.014 15.3 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 ORY52921.1 - 0.11 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 ORY52921.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DEAD PF00270.29 ORY52922.1 - 3.1e-39 134.5 0.0 5.4e-39 133.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 ORY52922.1 - 2.2e-33 114.9 0.2 1.2e-31 109.3 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY52922.1 - 5.1e-06 26.6 0.4 1.6e-05 25.0 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SDA1 PF05285.12 ORY52922.1 - 0.015 14.7 10.4 0.023 14.1 10.4 1.3 1 0 0 1 1 1 0 SDA1 AAA_19 PF13245.6 ORY52922.1 - 0.018 15.4 0.0 0.042 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 ORY52922.1 - 0.036 12.4 6.7 0.051 11.9 6.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Nha1_C PF08619.10 ORY52922.1 - 0.069 12.3 11.9 0.1 11.8 11.9 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Asp_Glu_race PF01177.22 ORY52922.1 - 0.16 11.8 0.0 8.5 6.1 0.0 2.8 3 0 0 3 3 3 0 Asp/Glu/Hydantoin racemase Nop14 PF04147.12 ORY52922.1 - 0.28 9.4 14.2 0.38 8.9 14.2 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 ORY52922.1 - 0.48 8.5 18.5 0.21 9.7 16.2 1.5 2 0 0 2 2 2 0 DNA polymerase phi Pox_Ag35 PF03286.14 ORY52922.1 - 0.72 9.6 12.5 1.6 8.4 12.5 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BUD22 PF09073.10 ORY52922.1 - 2.7 7.2 20.0 4.1 6.7 20.0 1.2 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.12 ORY52922.1 - 2.9 6.4 19.4 4.7 5.7 19.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cwf_Cwc_15 PF04889.12 ORY52922.1 - 5.1 6.7 19.9 8.8 6.0 19.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 ORY52922.1 - 7.5 6.0 16.9 13 5.3 16.9 1.3 1 0 0 1 1 1 0 PPP4R2 Glyco_hydro_18 PF00704.28 ORY52923.1 - 1.2e-54 186.2 1.2 1.4e-54 186.0 1.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 ORY52924.1 - 1.4e-37 130.1 0.3 1.6e-37 129.9 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GHL10 PF02638.15 ORY52924.1 - 0.0033 16.5 0.0 0.0043 16.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 Glyco_hydro_18 PF00704.28 ORY52925.1 - 8.7e-58 196.5 4.0 1.1e-57 196.1 4.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 WAP PF00095.21 ORY52925.1 - 0.18 12.2 6.1 0.32 11.4 6.1 1.3 1 0 0 1 1 1 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' SUZ PF12752.7 ORY52926.1 - 0.01 16.6 14.5 0.01 16.6 14.5 4.2 4 1 0 4 4 4 0 SUZ domain Aldo_ket_red PF00248.21 ORY52927.1 - 1.6e-82 277.1 0.0 1.9e-82 276.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ABC_tran PF00005.27 ORY52928.1 - 1.6e-31 109.6 0.0 4.6e-31 108.2 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 ORY52928.1 - 5.7e-17 62.5 1.3 1.2e-11 45.0 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 ORY52928.1 - 5.3e-10 38.9 34.2 7.9e-10 38.4 34.2 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein SMC_N PF02463.19 ORY52928.1 - 8e-06 25.4 0.3 0.0033 16.9 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 ORY52928.1 - 0.00082 19.2 0.0 0.23 11.2 0.0 2.2 1 1 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 ORY52928.1 - 0.012 15.8 0.0 0.1 12.9 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 ORY52928.1 - 0.017 14.3 0.1 0.033 13.4 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 ORY52928.1 - 0.018 14.7 0.1 0.037 13.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 ORY52928.1 - 0.025 15.1 0.1 0.052 14.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 ORY52928.1 - 0.046 13.6 0.0 0.097 12.6 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 ORY52928.1 - 0.087 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Pkinase PF00069.25 ORY52929.1 - 2.6e-07 30.3 0.0 2.1e-05 24.0 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain RMP PF14996.6 ORY52930.1 - 2.5e-23 83.0 5.1 2.5e-23 83.0 5.1 2.8 1 1 0 2 2 2 1 Retinal Maintenance RNA_pol_Rpb4 PF03874.16 ORY52930.1 - 0.059 13.7 0.7 0.19 12.1 0.4 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb4 DUF1387 PF07139.11 ORY52930.1 - 1.3 8.6 8.2 1.8 8.2 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Myc_N PF01056.18 ORY52931.1 - 0.99 9.2 11.2 0.013 15.4 2.7 2.1 1 1 1 2 2 2 0 Myc amino-terminal region CDC45 PF02724.14 ORY52931.1 - 4.6 5.4 11.7 0.28 9.4 3.5 2.0 2 0 0 2 2 2 0 CDC45-like protein DNA_pol_phi PF04931.13 ORY52931.1 - 9.2 4.2 7.2 13 3.7 7.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi zf-RING_UBOX PF13445.6 ORY52932.1 - 3e-10 40.0 16.1 5.7e-06 26.3 7.4 3.4 2 1 1 3 3 3 2 RING-type zinc-finger zf-C3HC4_4 PF15227.6 ORY52932.1 - 3.6e-10 39.8 26.4 6e-06 26.3 1.5 2.9 3 0 0 3 3 3 2 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 ORY52932.1 - 7.5e-09 35.3 22.0 3e-07 30.2 15.3 2.7 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY52932.1 - 1.4e-08 34.4 22.3 2e-06 27.5 16.0 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY52932.1 - 8.3e-07 28.8 27.5 8.7e-06 25.5 13.3 2.7 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY52932.1 - 1.2e-06 28.4 22.3 0.00033 20.5 15.1 2.9 3 0 0 3 3 3 2 zinc-RING finger domain zf-RING_2 PF13639.6 ORY52932.1 - 4.3e-05 23.7 14.8 4.3e-05 23.7 14.8 3.0 3 1 0 3 3 3 2 Ring finger domain Prok-RING_4 PF14447.6 ORY52932.1 - 4.5e-05 23.2 26.9 0.00055 19.7 13.1 3.0 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 U-box PF04564.15 ORY52932.1 - 0.0053 16.9 0.3 0.33 11.2 0.0 2.9 3 0 0 3 3 3 1 U-box domain zf-RING_10 PF16685.5 ORY52932.1 - 0.026 14.7 9.8 0.026 14.7 9.8 2.6 3 0 0 3 3 3 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 ORY52932.1 - 0.53 10.6 11.5 2.4 8.5 11.5 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain IBR PF01485.21 ORY52932.1 - 1.2 9.4 20.3 0.74 10.1 8.4 3.9 2 2 1 3 3 3 0 IBR domain, a half RING-finger domain zf-RING_4 PF14570.6 ORY52932.1 - 1.5 8.6 26.0 0.31 10.9 11.9 3.4 4 1 0 4 4 4 0 RING/Ubox like zinc-binding domain NMT PF01233.19 ORY52933.1 - 2.1e-75 252.0 0.1 3.6e-75 251.2 0.1 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 ORY52933.1 - 3.9e-71 238.9 0.0 5.9e-71 238.3 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_1 PF00583.25 ORY52933.1 - 0.044 14.0 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family SOG2 PF10428.9 ORY52934.1 - 0.84 8.8 27.3 1.3 8.2 27.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SOBP PF15279.6 ORY52934.1 - 0.91 10.1 18.7 1.6 9.3 18.7 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein GRAM PF02893.20 ORY52937.1 - 3.3e-19 68.9 0.3 5.9e-19 68.0 0.3 1.3 1 0 0 1 1 1 1 GRAM domain Histone PF00125.24 ORY52938.1 - 3.3e-21 76.0 0.2 4.4e-21 75.6 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY52938.1 - 2.6e-06 27.6 0.1 5.9e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 ORY52938.1 - 0.00015 22.2 0.0 0.00025 21.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1931 PF09123.11 ORY52938.1 - 0.15 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) Histone_H2A_C PF16211.5 ORY52939.1 - 2.3e-19 68.8 0.7 5e-19 67.7 0.7 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 ORY52939.1 - 4.5e-16 59.4 0.0 5.8e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 ORY52939.1 - 3.2e-05 24.1 0.0 4.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Aldedh PF00171.22 ORY52940.1 - 3.1e-147 490.8 0.4 3.5e-147 490.7 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 ORY52940.1 - 0.0016 17.9 0.1 0.0061 16.0 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Dynamitin PF04912.14 ORY52941.1 - 6.4e-22 78.4 1.4 1.1e-21 77.7 1.4 1.4 1 1 0 1 1 1 1 Dynamitin Dynactin_p22 PF07426.11 ORY52941.1 - 0.048 13.5 0.5 0.11 12.3 0.1 1.8 2 0 0 2 2 2 0 Dynactin subunit p22 LST1 PF05083.13 ORY52941.1 - 0.2 12.0 0.1 0.52 10.6 0.1 1.7 1 0 0 1 1 1 0 LST-1 protein FUSC PF04632.12 ORY52941.1 - 0.31 9.5 4.2 0.51 8.8 4.2 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF4378 PF14309.6 ORY52942.1 - 0.00012 22.5 0.0 0.00012 22.5 0.0 4.2 5 1 0 5 5 5 1 Domain of unknown function (DUF4378) Sec16 PF12932.7 ORY52942.1 - 3.7 8.1 10.5 17 6.1 0.9 3.4 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region Dna2 PF08696.11 ORY52942.1 - 8.7 6.1 11.0 1.1 9.0 4.4 3.1 3 0 0 3 3 3 0 DNA replication factor Dna2 MRG PF05712.13 ORY52943.1 - 0.033 13.5 0.1 0.048 13.0 0.1 1.2 1 0 0 1 1 1 0 MRG Mesd PF10185.9 ORY52943.1 - 0.065 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Chaperone for wingless signalling and trafficking of LDL receptor Glyco_transf_90 PF05686.12 ORY52944.1 - 2.2e-17 63.1 5.7 1.3e-15 57.2 3.4 3.5 2 1 0 2 2 2 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 ORY52944.1 - 0.0018 18.6 0.0 0.006 16.9 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 HTH_6 PF01418.17 ORY52944.1 - 0.18 11.8 0.2 2 8.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family IncD PF17628.2 ORY52944.1 - 0.22 11.3 0.1 0.4 10.5 0.1 1.3 1 0 0 1 1 1 0 Inclusion membrane protein D Promethin PF16015.5 ORY52944.1 - 7.4 6.6 9.5 0.21 11.5 3.2 1.6 2 0 0 2 2 2 0 Promethin Hydrolase_4 PF12146.8 ORY52945.1 - 1.2e-40 139.3 0.0 2.4e-40 138.3 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY52945.1 - 4.4e-05 24.2 0.3 5.4e-05 23.9 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 ORY52945.1 - 0.018 14.7 0.2 0.37 10.4 0.2 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 ORY52945.1 - 0.056 12.0 0.0 0.083 11.4 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II AXE1 PF05448.12 ORY52945.1 - 0.12 11.0 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 ORY52945.1 - 0.19 11.2 0.5 1.1 8.6 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF3040 PF11239.8 ORY52946.1 - 1 9.7 3.4 2.8 8.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) COX4_pro_2 PF07835.12 ORY52946.1 - 1.2 9.3 0.1 1.2 9.3 0.1 2.8 3 0 0 3 3 3 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF4133 PF13571.6 ORY52946.1 - 8.4 6.8 7.7 3.1 8.2 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4133) Pkinase PF00069.25 ORY52947.1 - 1.8e-77 260.3 0.0 1.8e-77 260.3 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY52947.1 - 2.4e-36 125.3 0.0 2.4e-36 125.3 0.0 2.4 1 1 0 2 2 2 1 Protein tyrosine kinase V_ATPase_I PF01496.19 ORY52947.1 - 0.04 11.8 16.0 0.052 11.5 16.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.15 ORY52947.1 - 0.43 10.1 21.7 0.67 9.5 21.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_23 PF13476.6 ORY52947.1 - 6.1 7.3 22.8 12 6.3 22.8 1.6 1 0 0 1 1 1 0 AAA domain PAT1 PF09770.9 ORY52947.1 - 8.3 4.5 44.2 11 4.2 44.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Kri1_C PF12936.7 ORY52948.1 - 1.2e-28 99.1 0.4 1.2e-28 99.1 0.4 5.5 6 0 0 6 6 6 1 KRI1-like family C-terminal Kri1 PF05178.12 ORY52948.1 - 2.9e-23 82.4 12.3 2.9e-23 82.4 12.3 7.5 6 2 2 8 8 8 1 KRI1-like family ATP-synt_D PF01813.17 ORY52949.1 - 1.2e-50 172.1 11.7 3.3e-40 138.0 2.5 2.5 2 1 1 3 3 3 2 ATP synthase subunit D DUF4300 PF14133.6 ORY52949.1 - 0.025 14.3 0.7 0.031 14.0 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4300) APG6_N PF17675.1 ORY52949.1 - 0.081 13.4 0.2 0.081 13.4 0.2 1.7 2 1 0 2 2 2 0 Apg6 coiled-coil region PMEI PF04043.15 ORY52949.1 - 0.16 12.3 0.2 0.24 11.7 0.2 1.4 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor Streptin-Immun PF11083.8 ORY52949.1 - 0.39 11.1 4.7 0.21 12.0 1.5 2.0 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein zf-C3HC4_4 PF15227.6 ORY52950.1 - 6e-05 23.1 7.1 0.00013 22.0 7.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 ORY52950.1 - 7.3e-05 22.6 8.1 0.00013 21.7 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY52950.1 - 0.00012 21.9 9.5 0.00024 20.9 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY52950.1 - 0.00014 21.8 9.1 0.0003 20.8 9.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 ORY52950.1 - 0.0039 17.0 8.9 0.027 14.3 9.3 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 ORY52950.1 - 0.0059 16.6 8.4 0.012 15.5 8.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 ORY52950.1 - 0.007 16.2 6.9 0.014 15.2 6.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 ORY52950.1 - 0.0077 16.1 2.2 0.017 15.0 2.2 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein C1_1 PF00130.22 ORY52950.1 - 0.016 15.0 2.8 0.032 14.1 2.8 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.6 ORY52950.1 - 0.051 13.9 8.4 0.1 13.0 8.4 1.5 1 0 0 1 1 1 0 Ring finger domain DZR PF12773.7 ORY52950.1 - 0.23 11.5 3.5 0.46 10.6 3.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-Nse PF11789.8 ORY52950.1 - 1.8 8.4 6.9 0.85 9.5 3.7 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Glyco_transf_22 PF03901.17 ORY52951.1 - 5.6e-85 286.1 21.5 6.9e-85 285.8 21.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.6 ORY52951.1 - 0.013 15.7 13.4 0.013 15.7 13.4 2.2 1 1 1 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase TPR_17 PF13431.6 ORY52951.1 - 0.049 14.0 0.0 0.59 10.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1866 PF08952.11 ORY52952.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) TPR_12 PF13424.6 ORY52955.1 - 0.026 14.8 0.0 0.2 12.0 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat CYTL1 PF15153.6 ORY52955.1 - 0.028 14.3 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 Cytokine-like protein 1 Rotamase_3 PF13616.6 ORY52955.1 - 0.18 12.3 0.0 0.28 11.7 0.0 1.3 1 0 0 1 1 1 0 PPIC-type PPIASE domain TPR_12 PF13424.6 ORY52956.1 - 5.9e-31 106.6 14.2 1.4e-12 47.7 0.4 5.9 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 ORY52956.1 - 1e-25 88.8 1.0 8.2e-09 35.1 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 ORY52956.1 - 0.0034 17.1 3.5 0.0052 16.6 0.5 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 ORY52956.1 - 0.0085 16.1 6.3 0.15 12.3 0.4 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY52956.1 - 0.096 12.9 7.8 0.37 11.1 0.5 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Phage_Treg PF04761.12 ORY52956.1 - 0.13 12.4 0.4 1.8 8.7 0.0 2.8 3 0 0 3 3 3 0 Lactococcus bacteriophage putative transcription regulator ssDBP_DBD PF18361.1 ORY52956.1 - 0.14 12.2 0.0 0.45 10.6 0.0 1.8 1 0 0 1 1 1 0 Single stranded DNA-binding protein ss DNA binding domain TPR_19 PF14559.6 ORY52956.1 - 0.54 10.8 6.5 0.2 12.2 0.9 3.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY52956.1 - 1.4 9.7 3.5 4.8 8.0 0.4 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 ORY52956.1 - 3.1 7.9 5.4 2.5 8.2 2.6 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 ORY52957.1 - 6.3e-27 93.7 3.0 2.8e-07 30.7 0.0 7.0 3 2 5 8 8 8 6 Tetratricopeptide repeat TPR_10 PF13374.6 ORY52957.1 - 5.6e-11 42.0 1.6 0.0028 17.5 0.0 6.9 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY52957.1 - 9.2e-08 31.6 4.5 0.004 16.9 0.4 5.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY52957.1 - 2.9e-06 26.9 3.4 0.01 15.9 0.2 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY52957.1 - 4.5e-05 23.3 4.2 0.082 13.2 0.2 5.5 7 0 0 7 7 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY52957.1 - 0.0099 16.1 2.4 0.14 12.4 0.1 3.9 6 0 0 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 ORY52957.1 - 0.015 15.2 6.0 3.1 8.0 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat PPR PF01535.20 ORY52957.1 - 0.076 13.3 5.2 7.9 7.0 0.1 5.1 5 1 1 6 6 6 0 PPR repeat RPN6_N PF18055.1 ORY52957.1 - 0.24 11.8 2.4 11 6.4 0.4 2.8 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain RPN7 PF10602.9 ORY52957.1 - 0.46 10.2 3.8 0.73 9.5 0.2 3.1 2 2 0 3 3 3 0 26S proteasome subunit RPN7 TPR_6 PF13174.6 ORY52957.1 - 2.9 8.7 8.6 1.5 9.6 0.2 4.5 5 1 0 5 5 3 0 Tetratricopeptide repeat Pan3_PK PF18101.1 ORY52958.1 - 6.4e-67 223.8 0.1 9.9e-67 223.2 0.1 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 ORY52958.1 - 1.1e-05 25.0 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinetochor_Ybp2 PF08568.10 ORY52959.1 - 1.2e-07 30.6 2.6 0.00074 18.1 0.1 2.4 2 1 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin Trp_DMAT PF11991.8 ORY52959.1 - 0.048 13.1 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 Tryptophan dimethylallyltransferase FWWh PF14922.6 ORY52959.1 - 0.07 13.1 1.5 11 6.0 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function Mn_catalase PF05067.12 ORY52959.1 - 0.081 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Manganese containing catalase DUF760 PF05542.11 ORY52959.1 - 0.15 12.4 0.6 2.8 8.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF760) Cnd1 PF12717.7 ORY52959.1 - 7.6 6.6 7.7 5.8 6.9 0.3 3.5 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 TAFII55_N PF04658.13 ORY52960.1 - 1.5e-44 151.5 0.1 1.5e-44 151.5 0.1 1.8 2 0 0 2 2 2 1 TAFII55 protein conserved region FTA4 PF13093.6 ORY52960.1 - 0.045 13.6 2.4 0.076 12.9 2.4 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 TSC22 PF01166.18 ORY52960.1 - 0.051 13.9 1.6 0.15 12.4 1.6 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family BUD22 PF09073.10 ORY52960.1 - 0.18 11.1 14.3 0.22 10.9 14.3 1.1 1 0 0 1 1 1 0 BUD22 FAM76 PF16046.5 ORY52960.1 - 1.6 8.0 5.8 2.6 7.3 5.6 1.4 1 1 0 1 1 1 0 FAM76 protein Spc7 PF08317.11 ORY52960.1 - 10 4.9 14.5 0.26 10.1 8.1 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein PCI PF01399.27 ORY52961.1 - 1.6e-21 76.8 0.4 1.9e-20 73.3 0.0 2.6 2 1 0 2 2 2 1 PCI domain RPN5_C PF18098.1 ORY52961.1 - 5.2e-17 61.6 3.3 6e-17 61.5 1.9 2.0 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain Ldh_1_N PF00056.23 ORY52962.1 - 1.8e-45 154.5 0.2 2.7e-45 153.9 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 ORY52962.1 - 1.2e-44 152.2 0.0 1.9e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 ORY52962.1 - 0.011 14.8 0.0 0.018 14.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family HECT PF00632.25 ORY52963.1 - 7.7e-84 281.8 0.0 1.1e-83 281.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) TIP41 PF04176.13 ORY52963.1 - 0.01 15.4 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 TIP41-like family MSP7_C PF12948.7 ORY52963.1 - 0.019 15.6 0.1 2.9 8.6 0.0 2.7 2 0 0 2 2 2 0 MSP7-like protein C-terminal domain Plasmo_rep PF12135.8 ORY52963.1 - 0.027 14.0 0.0 0.072 12.6 0.0 1.7 1 0 0 1 1 1 0 Plasmodium repeat family Frataxin_Cyay PF01491.16 ORY52964.1 - 2.7e-32 111.0 0.0 3.7e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Ribosomal_L9_C PF03948.14 ORY52965.1 - 1.3e-12 47.9 0.1 2.3e-12 47.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 ORY52965.1 - 2.1e-10 40.0 0.1 4.5e-10 38.9 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain CAF1 PF04857.20 ORY52966.1 - 1.5e-18 67.0 0.3 4.4e-08 32.6 0.1 2.5 1 1 0 2 2 2 2 CAF1 family ribonuclease Kinesin PF00225.23 ORY52967.1 - 4.2e-87 292.2 3.0 4.2e-87 292.2 3.0 3.0 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 ORY52967.1 - 6.6e-20 71.6 5.5 6.3e-19 68.4 0.8 3.5 2 2 1 3 3 3 1 Microtubule binding EzrA PF06160.12 ORY52967.1 - 0.0011 17.3 18.3 0.0011 17.3 18.3 4.3 3 2 1 4 4 4 1 Septation ring formation regulator, EzrA HIP1_clath_bdg PF16515.5 ORY52967.1 - 0.0011 19.5 9.2 0.0011 19.5 9.2 7.4 2 1 2 6 6 6 1 Clathrin-binding domain of Huntingtin-interacting protein 1 Filament PF00038.21 ORY52967.1 - 0.0029 17.3 11.9 0.0029 17.3 11.9 5.0 2 1 2 4 4 4 2 Intermediate filament protein cwf18 PF08315.12 ORY52968.1 - 1e-16 61.9 9.6 3.4e-16 60.2 9.6 1.9 1 1 0 1 1 1 1 cwf18 pre-mRNA splicing factor Suppressor_APC PF11414.8 ORY52968.1 - 0.085 12.9 3.2 0.21 11.7 3.2 1.7 1 1 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein GATase_7 PF13537.6 ORY52969.1 - 1.5e-12 47.5 0.0 2.6e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ORY52969.1 - 3e-12 46.9 0.0 6.4e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 ORY52969.1 - 1e-05 25.1 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Citrate_synt PF00285.21 ORY52970.1 - 4.4e-82 276.0 0.0 6.8e-82 275.4 0.0 1.3 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain FliD_N PF02465.18 ORY52971.1 - 1.9 9.2 10.4 0.81 10.4 0.2 2.5 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus RabGAP-TBC PF00566.18 ORY52972.1 - 5.2e-34 117.8 0.0 6.6e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3464 PF11947.8 ORY52972.1 - 0.0065 16.2 0.0 0.0095 15.7 0.0 1.2 1 0 0 1 1 1 1 Photosynthesis affected mutant 68 Mhr1 PF12829.7 ORY52972.1 - 0.09 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination Mis14 PF08641.12 ORY52973.1 - 7.3e-05 23.1 1.2 0.0002 21.7 1.2 1.8 1 1 0 1 1 1 1 Kinetochore protein Mis14 like ADIP PF11559.8 ORY52973.1 - 0.031 14.4 2.6 0.06 13.4 2.6 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Helicase_C PF00271.31 ORY52974.1 - 4.4e-15 56.0 0.1 1.6e-14 54.2 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY52974.1 - 1.6e-05 24.7 0.0 3.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ORY52974.1 - 0.00085 19.6 0.5 0.0056 17.0 0.1 2.7 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 ORY52974.1 - 0.033 13.2 0.0 0.076 12.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF4149 PF13664.6 ORY52976.1 - 0.039 14.3 0.8 0.054 13.8 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4149) DUF5336 PF17270.2 ORY52976.1 - 0.83 9.3 3.6 1.1 8.9 3.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5336) G8 PF10162.9 ORY52977.1 - 1.6e-20 73.4 0.2 3.2e-19 69.2 0.1 2.5 2 0 0 2 2 2 1 G8 domain Beta_helix PF13229.6 ORY52977.1 - 0.65 9.8 13.6 0.031 14.1 2.2 3.5 3 0 0 3 3 3 0 Right handed beta helix region SAICAR_synt PF01259.18 ORY52979.1 - 1.8e-104 348.8 0.0 2.3e-104 348.5 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase ECR1_N PF14382.6 ORY52980.1 - 1.8e-11 43.6 1.2 3.4e-11 42.7 1.2 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region RLI PF04068.15 ORY52980.1 - 0.059 13.2 2.1 0.12 12.2 2.1 1.5 1 0 0 1 1 1 0 Possible Fer4-like domain in RNase L inhibitor, RLI DUF1129 PF06570.11 ORY52981.1 - 0.014 14.9 0.3 0.015 14.8 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2842 PF11003.8 ORY52981.1 - 0.047 14.0 1.0 0.083 13.2 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2842) MFS_1 PF07690.16 ORY52982.1 - 1.1e-38 133.1 48.6 1.3e-38 132.9 48.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY52982.1 - 2.7e-13 49.6 27.4 3.8e-10 39.2 14.0 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 ORY52982.1 - 4e-07 29.2 9.4 4e-07 29.2 9.4 2.9 1 1 0 2 2 2 1 MFS_1 like family OATP PF03137.20 ORY52982.1 - 1.9e-05 23.2 2.4 1.9e-05 23.2 2.4 2.9 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 ORY52983.1 - 1.1e-27 96.9 27.3 1.3e-27 96.6 27.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY52983.1 - 2.2e-08 33.4 20.7 2.3e-08 33.4 18.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 ORY52983.1 - 4.9e-05 22.4 11.5 4.9e-05 22.4 11.5 1.4 2 0 0 2 2 2 1 MFS_1 like family OATP PF03137.20 ORY52983.1 - 0.00023 19.6 3.5 0.00033 19.1 3.5 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family BT1 PF03092.16 ORY52983.1 - 0.1 10.8 6.8 0.023 13.0 1.2 2.0 2 0 0 2 2 2 0 BT1 family Tmemb_9 PF05434.11 ORY52984.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 TMEM9 Thiolase_N PF00108.23 ORY52985.1 - 8.9e-53 179.3 1.8 2e-49 168.3 1.8 2.3 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 ORY52985.1 - 8.5e-21 73.9 2.8 1.8e-20 72.8 2.8 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 ORY52985.1 - 0.033 13.8 1.8 0.037 13.6 0.3 1.8 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain CAP PF00188.26 ORY52986.1 - 7.4e-16 59.1 0.1 9.6e-16 58.8 0.1 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ABC1 PF03109.16 ORY52987.1 - 6.8e-23 81.1 0.1 1.5e-22 80.0 0.1 1.6 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 ORY52987.1 - 0.004 16.6 0.0 0.96 8.8 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain NPR3 PF03666.13 ORY52988.1 - 2.7e-57 194.6 0.0 3.9e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 YibE_F PF07907.11 ORY52989.1 - 0.011 15.2 1.0 0.014 14.9 1.0 1.0 1 0 0 1 1 1 0 YibE/F-like protein RGS12_us2 PF16611.5 ORY52989.1 - 0.033 14.6 0.2 0.05 14.0 0.2 1.2 1 0 0 1 1 1 0 Unstructured region between RBD and GoLoco Ni_hydr_CYTB PF01292.20 ORY52990.1 - 0.017 14.7 1.2 0.021 14.4 1.2 1.0 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF202 PF02656.15 ORY52990.1 - 0.26 11.8 2.4 0.4 11.2 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF202) TRI9 PF08195.11 ORY52991.1 - 0.072 13.0 0.3 0.17 11.8 0.3 1.6 1 0 0 1 1 1 0 TRI9 protein DUF2070 PF09843.9 ORY52992.1 - 9.8 4.3 19.2 12 4.0 19.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Pkinase PF00069.25 ORY52993.1 - 1.1e-54 185.6 0.0 5.6e-49 166.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY52993.1 - 1.4e-34 119.6 0.0 5.2e-30 104.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 ORY52993.1 - 6e-06 25.8 0.0 1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY52993.1 - 0.042 13.8 0.4 0.1 12.5 0.4 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family SET PF00856.28 ORY52994.1 - 3.6e-14 53.5 1.1 1.3e-13 51.7 0.2 2.4 2 0 0 2 2 2 1 SET domain SRI PF08236.11 ORY52994.1 - 1.8e-11 44.0 1.9 4.1e-11 42.9 1.9 1.6 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain AWS PF17907.1 ORY52994.1 - 2.5e-11 43.4 8.1 1.1e-10 41.4 8.1 2.2 1 0 0 1 1 1 1 AWS domain WW PF00397.26 ORY52994.1 - 1.5e-07 31.3 0.1 7.3e-07 29.2 0.2 2.1 2 0 0 2 2 2 1 WW domain Med26 PF08711.11 ORY52994.1 - 0.0014 18.6 0.4 0.0049 16.9 0.0 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain DUF4704 PF15787.5 ORY52994.1 - 0.005 16.1 0.6 0.0079 15.5 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4704) Glyco_hyd_101C PF17451.2 ORY52994.1 - 0.041 14.2 0.2 0.22 11.8 0.1 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain DUF2924 PF11149.8 ORY52994.1 - 0.14 12.5 0.0 0.43 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) RNA_pol_I_A49 PF06870.12 ORY52995.1 - 7.8e-71 239.0 2.2 8.8e-71 238.8 2.2 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor zf-C2H2_4 PF13894.6 ORY52996.1 - 3e-08 33.8 0.5 0.0098 16.7 0.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY52996.1 - 5.8e-06 26.5 0.7 0.054 14.0 0.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY52996.1 - 0.00061 20.1 0.1 0.079 13.4 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 ORY52996.1 - 0.016 15.2 0.6 3 8.0 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger TFIIA PF03153.13 ORY52996.1 - 0.024 14.7 9.8 0.031 14.3 9.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_11 PF17123.5 ORY52996.1 - 0.035 13.9 0.0 0.074 12.8 0.0 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-C2H2_3rep PF18868.1 ORY52996.1 - 0.32 11.7 4.3 1.7 9.3 2.1 2.5 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats FliD_N PF02465.18 ORY52996.1 - 2.4 8.9 7.0 0.5 11.1 1.7 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus PilP PF04351.13 ORY52996.1 - 4.5 7.2 9.5 0.26 11.2 4.2 1.6 2 0 0 2 2 2 0 Pilus assembly protein, PilP Virul_fac_BrkB PF03631.15 ORY52998.1 - 0.047 13.3 8.2 0.058 13.0 8.2 1.0 1 0 0 1 1 1 0 Virulence factor BrkB DAP10 PF07213.11 ORY52998.1 - 0.31 11.0 3.5 0.41 10.6 0.1 2.1 1 1 1 2 2 2 0 DAP10 membrane protein PRIMA1 PF16101.5 ORY52998.1 - 4.5 7.3 5.3 1.4 9.0 0.6 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 SWI-SNF_Ssr4 PF08549.10 ORY52999.1 - 5.4e-05 22.0 0.0 6.5e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) DUF3385 PF11865.8 ORY53000.1 - 5.8e-33 114.1 11.5 5.5e-27 94.6 0.2 5.7 5 1 1 6 6 6 2 Domain of unknown function (DUF3385) HEAT_2 PF13646.6 ORY53000.1 - 4.3e-09 36.6 3.0 0.0057 17.0 0.3 5.9 5 2 1 6 6 6 3 HEAT repeats HEAT PF02985.22 ORY53000.1 - 5.4e-07 29.3 18.4 0.16 12.3 0.0 9.9 12 0 0 12 12 12 2 HEAT repeat Cnd1 PF12717.7 ORY53000.1 - 6.8e-07 29.5 0.9 0.91 9.5 0.2 5.0 3 2 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 ORY53000.1 - 3.4e-06 27.4 2.6 6.3 7.4 0.1 7.0 8 1 1 9 9 9 2 HEAT-like repeat Stealth_CR2 PF11380.8 ORY53000.1 - 0.0015 18.7 0.3 0.51 10.5 0.1 2.7 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Tti2 PF10521.9 ORY53000.1 - 0.0018 17.8 4.7 1.2 8.6 0.2 4.2 2 1 0 3 3 3 2 Tti2 family DUF5578 PF17741.1 ORY53000.1 - 0.018 14.5 2.2 0.11 11.9 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5578) Sec7_N PF12783.7 ORY53000.1 - 0.033 14.1 0.2 0.033 14.1 0.2 4.7 2 2 1 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF4745 PF15923.5 ORY53000.1 - 0.089 12.8 0.2 0.35 10.9 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4745) CLASP_N PF12348.8 ORY53000.1 - 0.23 11.0 8.0 1.6 8.2 0.0 4.8 5 1 1 6 6 6 0 CLASP N terminal RTP1_C1 PF10363.9 ORY53000.1 - 0.41 10.9 3.1 66 3.7 0.0 4.3 3 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 FAT PF02259.23 ORY53001.1 - 1.1e-120 403.1 4.1 1.3e-46 159.4 0.0 4.1 3 1 1 4 4 4 3 FAT domain PI3_PI4_kinase PF00454.27 ORY53001.1 - 2e-71 240.7 0.1 3.9e-71 239.8 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 ORY53001.1 - 1e-57 194.5 7.5 8.5e-51 172.1 0.1 5.6 5 0 0 5 5 5 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 ORY53001.1 - 4.3e-35 120.1 0.4 1.9e-34 118.0 0.4 2.3 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 ORY53001.1 - 2.7e-14 52.7 1.1 6.7e-14 51.4 1.1 1.8 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 ORY53001.1 - 5.6e-12 45.9 4.8 0.057 13.8 0.0 7.7 8 2 1 9 9 7 4 HEAT repeats HEAT PF02985.22 ORY53001.1 - 4e-09 36.0 17.6 0.00076 19.5 0.0 10.1 11 0 0 11 11 11 1 HEAT repeat HEAT_EZ PF13513.6 ORY53001.1 - 1.8e-05 25.1 6.8 0.7 10.5 0.0 8.6 6 1 1 7 7 7 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 ORY53001.1 - 4.9e-05 23.8 0.4 22 5.7 0.0 6.1 6 1 1 7 7 6 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 ORY53001.1 - 8.1e-05 21.4 1.0 8.1e-05 21.4 1.0 3.1 4 1 0 4 4 4 1 Adaptin N terminal region Cnd1 PF12717.7 ORY53001.1 - 0.00025 21.1 0.2 0.041 13.9 0.1 4.0 2 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 ORY53001.1 - 0.00058 19.5 1.8 0.99 8.9 0.0 5.1 5 1 1 6 6 6 1 CLASP N terminal TPR_19 PF14559.6 ORY53001.1 - 0.0083 16.6 3.7 42 4.8 0.0 5.9 8 0 0 8 8 6 0 Tetratricopeptide repeat Sec7_N PF12783.7 ORY53001.1 - 0.01 15.7 6.5 1 9.2 0.0 3.9 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_7 PF13176.6 ORY53001.1 - 0.017 15.1 0.9 21 5.4 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat HEAT_PBS PF03130.16 ORY53001.1 - 0.018 15.7 0.6 91 4.2 0.1 5.5 5 0 0 5 5 3 0 PBS lyase HEAT-like repeat RTP1_C1 PF10363.9 ORY53001.1 - 0.03 14.5 0.6 31 4.8 0.0 4.7 4 1 1 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 TPR_2 PF07719.17 ORY53001.1 - 0.052 13.7 5.6 46 4.5 0.0 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY53001.1 - 0.052 13.8 3.7 26 5.1 0.0 4.7 5 0 0 5 5 3 0 Anaphase-promoting complex, cyclosome, subunit 3 IFRD PF05004.13 ORY53001.1 - 0.092 11.8 0.8 0.69 9.0 0.0 2.9 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) Baculo_PEP_C PF04513.12 ORY53001.1 - 0.1 12.7 0.0 1.4 9.0 0.0 2.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Xpo1 PF08389.12 ORY53001.1 - 0.35 10.9 5.1 1.7 8.7 0.0 4.5 5 0 0 5 5 5 0 Exportin 1-like protein TPR_16 PF13432.6 ORY53001.1 - 0.5 11.0 5.6 8.7 7.1 0.2 4.3 4 0 0 4 4 3 0 Tetratricopeptide repeat PI3_PI4_kinase PF00454.27 ORY53002.1 - 2.4e-77 260.1 0.2 4e-77 259.4 0.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 ORY53002.1 - 1.3e-47 162.7 1.2 1.9e-47 162.2 1.2 1.3 1 0 0 1 1 1 1 FAT domain FRB_dom PF08771.11 ORY53002.1 - 6.1e-47 158.1 0.2 2.4e-46 156.2 0.2 2.1 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain FATC PF02260.20 ORY53002.1 - 1.2e-16 60.2 1.4 4.3e-16 58.4 0.7 2.4 2 0 0 2 2 2 1 FATC domain ANAPC3 PF12895.7 ORY53002.1 - 0.075 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TetR_C_30 PF17939.1 ORY53002.1 - 0.1 12.8 0.1 4.4 7.6 0.1 2.6 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Glyco_hydro_20 PF00728.22 ORY53003.1 - 3.1e-61 207.7 0.0 8.4e-61 206.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 ORY53003.1 - 7.5e-10 39.7 0.5 1.4e-09 38.7 0.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 ORY53003.1 - 1.4e-07 32.2 0.6 7e-07 30.0 0.1 2.2 2 1 1 3 3 3 1 beta-acetyl hexosaminidase like UreF PF01730.16 ORY53005.1 - 0.01 16.4 0.1 0.019 15.5 0.1 1.3 1 0 0 1 1 1 0 UreF PELOTA_1 PF15608.6 ORY53005.1 - 0.057 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 PELOTA RNA binding domain FliP PF00813.20 ORY53005.1 - 0.81 9.5 3.0 10 5.9 0.1 2.7 3 0 0 3 3 3 0 FliP family Pkinase PF00069.25 ORY53006.1 - 4.6e-35 121.3 0.0 3.3e-22 79.1 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY53006.1 - 8.4e-23 81.0 0.0 1.3e-13 50.9 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase PBD PF00786.28 ORY53006.1 - 9.4e-13 48.3 0.0 2e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase PF00069.25 ORY53007.1 - 4.3e-31 108.2 1.9 1.2e-18 67.4 1.7 4.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 ORY53007.1 - 4.8e-18 65.4 0.4 1.1e-05 24.9 0.0 3.4 2 1 1 3 3 3 3 Protein tyrosine kinase PBD PF00786.28 ORY53007.1 - 1.5e-15 57.3 0.0 8.5e-15 54.9 0.0 2.3 2 0 0 2 2 2 1 P21-Rho-binding domain APH PF01636.23 ORY53007.1 - 0.012 15.6 0.7 0.073 13.0 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY53007.1 - 0.089 11.7 0.0 0.25 10.2 0.0 1.7 1 0 0 1 1 1 0 Haspin like kinase domain DUF1682 PF07946.14 ORY53007.1 - 0.5 9.5 18.5 0.78 8.9 18.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) FAM178 PF14816.6 ORY53007.1 - 0.77 8.7 6.9 1.4 7.8 6.9 1.3 1 0 0 1 1 1 0 Family of unknown function, FAM178 VSG_B PF13206.6 ORY53007.1 - 7.8 5.6 8.5 12 5.1 8.5 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain Pkinase PF00069.25 ORY53008.1 - 8.6e-65 218.7 0.0 1.4e-64 218.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY53008.1 - 2.2e-45 155.0 0.0 3.5e-45 154.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 ORY53008.1 - 1.8e-10 41.0 1.2 4.3e-10 39.8 0.0 2.2 2 0 0 2 2 2 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 ORY53008.1 - 3.8e-08 32.5 1.0 2.5e-07 29.8 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 ORY53008.1 - 3.4e-05 23.3 0.0 5.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH PF00169.29 ORY53008.1 - 0.0089 16.5 0.1 0.023 15.2 0.1 1.8 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 ORY53008.1 - 0.017 15.5 0.0 0.04 14.3 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain FTA2 PF13095.6 ORY53008.1 - 0.12 12.0 1.6 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pec_lyase_N PF04431.13 ORY53008.1 - 0.4 10.9 2.1 0.38 11.0 0.2 2.0 2 0 0 2 2 2 0 Pectate lyase, N terminus APH PF01636.23 ORY53008.1 - 0.56 10.1 1.9 1.1 9.1 0.1 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family SPG4 PF17325.2 ORY53008.1 - 4.6 8.4 11.9 15 6.7 0.9 2.6 2 0 0 2 2 2 0 Stationary phase protein 4 SOG2 PF10428.9 ORY53008.1 - 6.9 5.7 18.4 11 5.1 18.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Pkinase PF00069.25 ORY53009.1 - 7.9e-67 225.4 0.0 1.7e-66 224.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY53009.1 - 7.4e-48 163.1 0.0 1.4e-47 162.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 ORY53009.1 - 6.9e-22 77.6 0.0 1.9e-21 76.1 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 ORY53009.1 - 1e-13 51.7 0.9 2.2e-13 50.6 0.9 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 ORY53009.1 - 2.6e-06 27.0 0.0 5.3e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY53009.1 - 4.8e-05 22.3 0.0 4.8e-05 22.3 0.0 2.4 2 1 0 2 2 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY53009.1 - 0.00021 20.4 1.2 0.00044 19.3 1.2 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY53009.1 - 0.011 15.7 0.0 0.011 15.7 0.0 2.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family PH_11 PF15413.6 ORY53009.1 - 0.063 13.7 5.3 0.096 13.1 0.4 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain DUF4778 PF16008.5 ORY53009.1 - 0.14 12.2 8.8 0.24 11.4 8.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) CDC45 PF02724.14 ORY53009.1 - 0.52 8.5 19.3 0.75 8.0 19.3 1.2 1 0 0 1 1 1 0 CDC45-like protein LCD1 PF09798.9 ORY53009.1 - 2.2 6.7 9.5 3.1 6.2 9.5 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein Borrelia_P83 PF05262.11 ORY53009.1 - 3.5 6.0 18.3 5 5.5 18.3 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein GREB1 PF15782.5 ORY53009.1 - 3.6 4.6 7.9 4.8 4.2 7.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PA26 PF04636.13 ORY53009.1 - 4.5 6.1 10.0 7.2 5.4 10.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Metallophos PF00149.28 ORY53010.1 - 4e-31 109.1 0.1 5.5e-31 108.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 ORY53010.1 - 0.076 12.6 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain TAD2 PF18521.1 ORY53010.1 - 0.1 12.6 0.7 0.24 11.5 0.7 1.6 1 0 0 1 1 1 0 Transactivation domain 2 Sel1 PF08238.12 ORY53011.1 - 0.00019 22.0 0.0 0.15 12.8 0.0 3.7 3 0 0 3 3 3 1 Sel1 repeat REV PF00424.18 ORY53011.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) DUF2749 PF10907.8 ORY53012.1 - 0.19 11.9 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) PPR_2 PF13041.6 ORY53015.1 - 0.00012 22.2 0.0 0.027 14.7 0.0 3.1 3 0 0 3 3 3 1 PPR repeat family DUF5343 PF17278.2 ORY53015.1 - 0.01 16.0 0.6 0.023 14.8 0.6 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5343) PPR PF01535.20 ORY53015.1 - 0.14 12.4 7.8 15 6.1 0.2 5.0 6 0 0 6 6 6 0 PPR repeat MMR_HSR1_C PF08438.10 ORY53016.1 - 2.2e-32 112.0 0.0 3.8e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 ORY53016.1 - 2.4e-20 72.7 0.0 5.3e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 ORY53016.1 - 1.4e-08 34.5 0.0 4.9e-07 29.4 0.0 2.8 3 0 0 3 3 3 1 Ferrous iron transport protein B Dynamin_N PF00350.23 ORY53016.1 - 0.0039 17.3 0.1 0.0087 16.1 0.0 1.6 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 ORY53016.1 - 0.0069 16.3 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 ORY53016.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain PHD_3 PF13922.6 ORY53018.1 - 0.02 15.3 0.5 0.047 14.1 0.5 1.6 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx MFS_1 PF07690.16 ORY53019.1 - 2.8e-06 26.5 41.0 8.3e-06 25.0 24.8 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily Wyosine_form PF08608.12 ORY53020.1 - 3.8e-23 81.6 0.0 8.1e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 ORY53020.1 - 3.4e-21 76.3 0.0 1e-20 74.8 0.0 1.9 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 ORY53020.1 - 1.6e-14 54.3 0.1 6.8e-14 52.3 0.1 2.1 2 1 0 2 2 2 1 Flavodoxin Glycos_transf_2 PF00535.26 ORY53021.1 - 4.3e-35 121.0 0.0 5.2e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ORY53021.1 - 5.1e-13 49.4 0.0 6.2e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 ORY53021.1 - 3.6e-07 30.0 0.0 5.1e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 ORY53021.1 - 9.5e-05 21.9 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 ORY53021.1 - 0.0018 18.7 0.0 0.0036 17.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 AAR2 PF05282.11 ORY53022.1 - 2.2e-83 280.6 0.2 2.9e-83 280.2 0.2 1.1 1 0 0 1 1 1 1 AAR2 protein Carn_acyltransf PF00755.20 ORY53023.1 - 3.9e-182 607.0 0.0 4.8e-182 606.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Ribosomal_L18 PF17135.4 ORY53024.1 - 7.3e-93 309.2 1.9 8.1e-93 309.0 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 ORY53024.1 - 0.025 15.3 0.0 0.077 13.7 0.0 1.9 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A TBPIP PF07106.13 ORY53024.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain Nucleolin_bd PF16725.5 ORY53024.1 - 0.079 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Nucleolin binding domain Thiamine_BP PF01910.17 ORY53025.1 - 0.046 13.6 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 Thiamine-binding protein GST_N PF02798.20 ORY53026.1 - 0.025 14.9 0.0 0.055 13.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Aminotran_1_2 PF00155.21 ORY53027.1 - 4.5e-69 233.3 0.0 5.5e-69 233.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RRM_1 PF00076.22 ORY53028.1 - 8.2e-25 86.4 0.0 5.8e-12 45.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hat1_N PF10394.9 ORY53029.1 - 7.3e-14 52.3 0.0 1.4e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 ORY53029.1 - 1.8e-06 28.1 0.0 3.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 ORY53029.1 - 0.0064 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY53029.1 - 0.034 14.6 0.0 0.076 13.4 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 ORY53029.1 - 0.069 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family YABBY PF04690.13 ORY53030.1 - 8.5e-14 52.4 5.1 8.9e-14 52.4 5.1 1.0 1 0 0 1 1 1 1 YABBY protein HMG_box PF00505.19 ORY53030.1 - 7e-07 29.6 1.0 1.1e-06 28.9 1.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 ORY53030.1 - 1.1e-05 25.9 1.6 1.3e-05 25.6 1.6 1.2 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 ORY53030.1 - 0.00063 20.3 4.5 0.00076 20.0 4.5 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 WD40 PF00400.32 ORY53031.1 - 4.1e-45 150.8 23.0 2.1e-08 34.7 0.4 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY53031.1 - 4.4e-22 78.2 3.4 6.4e-07 29.6 0.0 6.5 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY53031.1 - 1.4e-07 30.8 2.3 0.28 10.1 0.3 4.3 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 ORY53031.1 - 3.3e-05 22.6 3.2 0.2 10.1 0.0 3.1 2 1 1 3 3 3 3 Cytochrome D1 heme domain Nup160 PF11715.8 ORY53031.1 - 0.0005 18.8 8.0 0.2 10.3 0.3 3.8 1 1 2 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 ORY53031.1 - 0.0011 18.4 0.0 3.6 6.8 0.0 3.0 3 0 0 3 3 3 2 WD40-like domain Frtz PF11768.8 ORY53031.1 - 0.0081 14.5 0.1 0.38 9.0 0.0 2.4 2 1 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 ORY53031.1 - 0.019 13.9 5.3 3.7 6.4 0.0 4.0 2 2 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain HPS3_N PF14761.6 ORY53031.1 - 0.17 11.4 0.0 1.8 8.0 0.0 2.3 2 1 1 3 3 3 0 Hermansky-Pudlak syndrome 3 Proteasome_A_N PF10584.9 ORY53031.1 - 2 8.2 3.3 11 5.8 0.1 3.2 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature CAP_GLY PF01302.25 ORY53032.1 - 0.0072 16.3 0.2 0.013 15.5 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain WD40 PF00400.32 ORY53034.1 - 2.7e-15 56.5 1.2 2e-05 25.3 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY53034.1 - 3.4e-08 33.7 0.0 0.56 10.5 0.0 5.0 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 ORY53034.1 - 0.066 13.2 0.0 5.2 7.1 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat PQQ_2 PF13360.6 ORY53034.1 - 0.091 12.3 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 PQQ-like domain WD40 PF00400.32 ORY53035.1 - 7.2e-17 61.5 8.2 0.00044 21.0 0.3 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY53035.1 - 1.9e-07 31.3 0.0 0.076 13.3 0.0 3.4 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 ORY53035.1 - 0.0006 18.0 0.1 0.22 9.5 0.0 2.6 2 1 1 3 3 3 2 IKI3 family eIF2A PF08662.11 ORY53035.1 - 0.0075 16.2 0.1 0.27 11.1 0.0 2.6 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 ORY53035.1 - 0.08 11.6 0.0 0.16 10.6 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF3605 PF12239.8 ORY53036.1 - 3.6e-14 53.4 0.2 9.2e-13 48.8 0.0 2.0 1 1 0 2 2 2 1 Protein of unknown function (DUF3605) Myb_DNA-binding PF00249.31 ORY53036.1 - 0.11 12.7 0.0 10 6.4 0.0 2.4 2 1 0 2 2 2 0 Myb-like DNA-binding domain p450 PF00067.22 ORY53037.1 - 2e-67 228.0 0.0 2.5e-67 227.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 gag-asp_proteas PF13975.6 ORY53038.1 - 0.016 15.7 0.0 4.4 7.9 0.0 2.3 1 1 1 2 2 2 0 gag-polyprotein putative aspartyl protease CENP-K PF11802.8 ORY53038.1 - 0.099 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Centromere-associated protein K zf-MYND PF01753.18 ORY53039.1 - 5.4e-11 42.4 10.3 9.4e-11 41.6 10.3 1.4 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 ORY53039.1 - 0.2 12.0 7.3 0.41 11.0 7.3 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF3605 PF12239.8 ORY53040.1 - 1.9e-11 44.5 1.2 1e-09 38.9 1.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) S36_mt PF10937.8 ORY53041.1 - 0.00048 21.7 7.0 0.0012 20.4 7.0 1.7 1 1 0 1 1 1 1 Ribosomal protein S36, mitochondrial SIS PF01380.22 ORY53043.1 - 0.026 14.4 0.1 0.063 13.1 0.1 1.6 1 1 0 1 1 1 0 SIS domain T2SSS_2 PF16549.5 ORY53043.1 - 0.12 12.4 0.3 0.12 12.4 0.3 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS) pilotin, S protein DnaJ PF00226.31 ORY53044.1 - 4e-22 78.1 0.5 4e-22 78.1 0.5 2.3 3 0 0 3 3 3 1 DnaJ domain RPT PF13446.6 ORY53044.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein Sec1 PF00995.23 ORY53045.1 - 3e-103 347.0 0.0 4.1e-103 346.6 0.0 1.1 1 0 0 1 1 1 1 Sec1 family SR-25 PF10500.9 ORY53045.1 - 4.6 6.8 5.9 8.5 5.9 5.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RRM_1 PF00076.22 ORY53046.1 - 5.3e-19 67.8 0.1 8.3e-19 67.2 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NTP_transferase PF00483.23 ORY53047.1 - 2.2e-12 47.1 0.0 6.2e-12 45.6 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 ORY53047.1 - 5.7e-08 33.3 0.0 1.1e-07 32.3 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 ORY53047.1 - 2.5e-05 23.8 16.0 0.00011 21.8 3.7 3.4 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) CHGN PF05679.16 ORY53047.1 - 0.00074 18.5 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Chondroitin N-acetylgalactosaminyltransferase DUF4954 PF16314.5 ORY53047.1 - 0.007 14.6 1.6 0.011 13.9 1.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 ORY53047.1 - 0.018 14.0 7.0 0.18 10.7 2.0 2.6 2 1 1 3 3 3 0 L-fucokinase CTP_transf_3 PF02348.19 ORY53047.1 - 0.04 13.8 0.2 0.093 12.6 0.0 1.6 2 0 0 2 2 2 0 Cytidylyltransferase Hexapep_2 PF14602.6 ORY53047.1 - 8.1 6.3 8.2 56 3.6 4.7 3.3 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase Pkinase PF00069.25 ORY53048.1 - 6.9e-49 166.6 0.0 7.7e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY53048.1 - 4.8e-39 134.2 0.0 5.6e-39 134.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY53048.1 - 0.00046 19.1 0.0 0.0007 18.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY53048.1 - 0.13 11.5 0.0 0.5 9.6 0.0 1.8 1 1 0 1 1 1 0 Kinase-like ARA70 PF12489.8 ORY53049.1 - 1.1e-06 28.9 13.3 1.9 8.7 0.0 5.0 5 0 0 5 5 5 4 Nuclear coactivator Malate_synthase PF01274.22 ORY53049.1 - 5.4e-05 21.7 10.7 5.8 5.1 0.1 5.2 5 0 0 5 5 5 5 Malate synthase PMM PF03332.13 ORY53049.1 - 7.4e-05 22.6 0.0 36 4.0 0.0 4.6 5 0 0 5 5 5 0 Eukaryotic phosphomannomutase Rsbr_N PF08678.10 ORY53049.1 - 0.0059 16.7 6.2 69 3.5 0.0 5.3 5 0 0 5 5 5 0 Rsbr N terminal DNApol_Exo PF18136.1 ORY53049.1 - 0.075 12.2 21.2 12 4.9 0.4 5.5 5 0 0 5 5 5 0 DNA mitochondrial polymerase exonuclease domain Gyro_capsid PF04162.12 ORY53049.1 - 0.089 11.3 25.1 3.1 6.2 0.4 5.0 5 0 0 5 5 5 0 Gyrovirus capsid protein (VP1) DctP PF03480.13 ORY53049.1 - 0.091 12.1 7.3 69 2.6 0.0 4.8 5 0 0 5 5 5 0 Bacterial extracellular solute-binding protein, family 7 TadF PF16964.5 ORY53049.1 - 0.26 11.0 2.2 2.6e+02 1.2 0.0 4.7 4 0 0 4 4 4 0 Putative tight adherence pilin protein F CCDC-167 PF15188.6 ORY53049.1 - 0.36 11.2 23.0 29 5.1 0.3 5.4 5 0 0 5 5 5 0 Coiled-coil domain-containing protein 167 SpmSyn_N PF17950.1 ORY53049.1 - 0.6 10.3 23.7 23 5.2 0.4 5.4 5 0 0 5 5 5 0 S-adenosylmethionine decarboxylase N -terminal Head-tail_con PF12236.8 ORY53049.1 - 0.85 8.0 25.0 7.5 4.9 0.5 5.1 5 0 0 5 5 5 0 Bacteriophage head to tail connecting protein HisG_C PF08029.11 ORY53049.1 - 0.88 9.8 3.8 3.4e+02 1.5 0.0 4.5 5 0 0 5 5 5 0 HisG, C-terminal domain DUF5320 PF17253.2 ORY53049.1 - 0.94 10.6 23.7 50 5.0 0.4 5.7 5 0 0 5 5 5 0 Family of unknown function (DUF5320) GSDH PF07995.11 ORY53050.1 - 2.1e-06 27.3 0.1 9.2e-06 25.2 0.0 1.8 2 0 0 2 2 2 1 Glucose / Sorbosone dehydrogenase DUF2661 PF10860.8 ORY53050.1 - 0.086 13.0 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2661) LigB PF02900.18 ORY53051.1 - 3e-08 33.1 0.0 6.2e-08 32.0 0.0 1.5 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Methyltransf_25 PF13649.6 ORY53052.1 - 0.0063 17.2 0.0 0.017 15.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 ORY53052.1 - 0.0076 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 ORY53052.1 - 0.023 14.2 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_31 PF13847.6 ORY53052.1 - 0.04 13.7 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 ORY53052.1 - 0.16 12.6 0.0 0.55 10.9 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Vezatin PF12632.7 ORY53053.1 - 0.19 11.1 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes Zip PF02535.22 ORY53054.1 - 2.6e-26 92.7 32.6 7.6e-18 64.8 0.0 3.3 2 1 1 3 3 3 3 ZIP Zinc transporter DUF2427 PF10348.9 ORY53054.1 - 0.8 9.5 4.3 0.94 9.3 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) Herpes_capsid PF06112.11 ORY53055.1 - 0.072 13.2 2.8 0.11 12.5 2.8 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein DUF1992 PF09350.10 ORY53056.1 - 2.5e-22 78.8 0.2 4.8e-22 77.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) Rbsn PF11464.8 ORY53056.1 - 0.032 13.9 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 Rabenosyn Rab binding domain SAP PF02037.27 ORY53058.1 - 7.8e-06 25.5 0.3 0.00022 20.9 0.1 2.3 2 0 0 2 2 2 1 SAP domain Rho_N PF07498.12 ORY53058.1 - 0.0008 19.3 2.8 0.32 11.0 0.1 3.6 3 0 0 3 3 3 2 Rho termination factor, N-terminal domain FANC_SAP PF18081.1 ORY53058.1 - 0.026 14.7 1.0 1.9 8.7 0.1 2.4 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain Fes1 PF08609.10 ORY53060.1 - 8.9e-24 84.2 1.9 1.2e-23 83.8 0.7 1.8 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT PF02985.22 ORY53060.1 - 9.4e-07 28.6 0.0 0.0045 17.1 0.0 2.7 2 0 0 2 2 2 2 HEAT repeat HEAT_EZ PF13513.6 ORY53060.1 - 1.8e-05 25.1 0.1 4.6e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 HEAT-like repeat HEAT_2 PF13646.6 ORY53060.1 - 2.7e-05 24.5 0.0 7.8e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 HEAT repeats PAS_8 PF13188.7 ORY53060.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 PAS domain Peptidase_M50 PF02163.22 ORY53061.1 - 3.3e-17 62.6 0.0 3.8e-16 59.1 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M50 PDZ_2 PF13180.6 ORY53061.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.6 1 0 0 1 1 1 0 PDZ domain GRAB PF10375.9 ORY53061.1 - 0.22 11.5 0.5 0.62 10.0 0.0 2.0 2 0 0 2 2 2 0 GRIP-related Arf-binding domain GATase_2 PF00310.21 ORY53062.1 - 1.8e-143 478.3 0.0 1.7e-142 475.0 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 ORY53062.1 - 6.5e-136 453.3 0.0 4.4e-134 447.3 0.0 2.4 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 ORY53062.1 - 1.3e-104 349.7 0.0 2.2e-101 339.0 0.0 2.3 2 0 0 2 2 2 2 Glutamate synthase central domain GXGXG PF01493.19 ORY53062.1 - 1.4e-83 279.2 6.0 2.7e-83 278.3 6.0 1.5 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.6 ORY53062.1 - 9.5e-21 73.7 0.1 2.5e-20 72.3 0.1 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 ORY53062.1 - 5e-20 71.9 1.0 2.6e-06 26.9 0.0 3.6 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 ORY53062.1 - 9.8e-08 32.1 0.2 2.9e-07 30.6 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 ORY53062.1 - 6.3e-06 25.6 0.1 0.06 12.6 0.1 2.6 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 ORY53062.1 - 1.8e-05 25.2 0.2 0.014 15.9 0.0 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 ORY53062.1 - 6.2e-05 21.9 0.1 0.00014 20.7 0.1 1.6 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_7 PF13241.6 ORY53062.1 - 9.3e-05 22.8 0.1 0.19 12.2 0.0 3.0 2 0 0 2 2 2 1 Putative NAD(P)-binding Amino_oxidase PF01593.24 ORY53062.1 - 0.00013 21.4 0.0 0.00026 20.4 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 ORY53062.1 - 0.00017 20.8 2.0 0.0015 17.7 0.3 2.7 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 ORY53062.1 - 0.00048 19.5 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 ORY53062.1 - 0.00049 19.6 0.9 0.001 18.5 0.9 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 ORY53062.1 - 0.00078 18.8 1.3 0.086 12.1 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY53062.1 - 0.00089 18.9 0.3 0.0092 15.6 0.1 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 ORY53062.1 - 0.011 15.1 0.0 0.08 12.3 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 ORY53062.1 - 0.029 13.6 0.1 0.084 12.1 0.1 1.7 1 0 0 1 1 1 0 Thi4 family NAD_binding_2 PF03446.15 ORY53062.1 - 0.033 14.4 0.2 0.44 10.7 0.1 2.7 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 ORY53062.1 - 0.069 12.8 0.1 0.2 11.3 0.1 1.9 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA YGGT PF02325.17 ORY53062.1 - 0.07 13.6 0.0 0.77 10.2 0.0 2.3 2 0 0 2 2 2 0 YGGT family Shikimate_DH PF01488.20 ORY53062.1 - 0.086 12.9 0.0 3.7 7.6 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 ORY53062.1 - 0.12 11.5 1.8 0.38 9.8 0.3 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A GATase_6 PF13522.6 ORY53062.1 - 0.14 12.4 0.0 0.37 11.0 0.0 1.7 1 0 0 1 1 1 0 Glutamine amidotransferase domain 3HCDH_N PF02737.18 ORY53062.1 - 0.15 11.9 1.1 0.38 10.6 0.1 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 ORY53062.1 - 0.17 11.9 0.1 0.52 10.3 0.1 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 ORY53062.1 - 0.2 11.2 0.5 0.5 9.9 0.1 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Carb_kinase PF01256.17 ORY53063.1 - 3.5e-23 82.3 0.0 2.7e-14 53.2 0.0 2.6 2 1 1 3 3 3 2 Carbohydrate kinase FYVE_2 PF02318.16 ORY53064.1 - 0.45 10.8 7.2 3.9 7.7 4.9 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger Agouti PF05039.12 ORY53064.1 - 7 7.4 6.7 10 6.9 2.6 2.1 1 1 1 2 2 2 0 Agouti protein F-box-like PF12937.7 ORY53066.1 - 7.9e-09 35.3 2.0 7.9e-09 35.3 2.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 ORY53066.1 - 0.00047 20.0 0.4 0.0024 17.7 0.4 2.3 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.6 ORY53066.1 - 0.0043 17.0 15.4 0.08 13.0 0.1 7.3 8 0 0 8 8 8 1 Leucine Rich repeat LRR_4 PF12799.7 ORY53066.1 - 0.0077 16.6 18.4 0.38 11.2 0.5 6.6 5 2 2 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY53066.1 - 0.021 14.6 13.9 0.28 11.0 0.2 6.0 6 1 0 6 6 6 0 Leucine rich repeat CbbQ_C PF08406.10 ORY53066.1 - 0.12 12.6 0.2 6 7.2 0.0 2.6 2 0 0 2 2 2 0 CbbQ/NirQ/NorQ C-terminal Cytochrom_B559 PF00283.19 ORY53068.1 - 0.55 9.7 2.8 3.6 7.1 1.1 2.4 2 0 0 2 2 2 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits PIF1 PF05970.14 ORY53069.1 - 0.014 14.6 0.1 0.055 12.6 0.0 1.8 2 0 0 2 2 2 0 PIF1-like helicase AAA_30 PF13604.6 ORY53069.1 - 0.075 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 ORY53069.1 - 0.1 12.5 0.0 0.61 10.0 0.0 2.1 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain SdrG_C_C PF10425.9 ORY53070.1 - 0.11 12.5 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 C-terminus of bacterial fibrinogen-binding adhesin Helitron_like_N PF14214.6 ORY53071.1 - 4e-09 37.0 3.3 1.2e-08 35.4 3.3 1.7 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus Tubulin PF00091.25 ORY53075.1 - 2e-46 158.7 0.0 4.4e-46 157.6 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORY53075.1 - 1.3e-43 148.2 0.1 2e-43 147.6 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 ORY53075.1 - 0.00088 19.0 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 ORY53075.1 - 0.012 14.9 0.0 0.043 13.0 0.0 1.8 2 0 0 2 2 2 0 Tubulin like Tubulin PF00091.25 ORY53076.1 - 2.7e-68 230.1 0.0 3.8e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 ORY53076.1 - 8.5e-52 174.6 0.0 1.4e-51 174.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 ORY53076.1 - 0.00079 19.1 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain FAM184 PF15665.5 ORY53077.1 - 0.098 12.4 31.3 1.4 8.7 10.8 2.2 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Filament PF00038.21 ORY53077.1 - 0.28 10.7 33.5 0.19 11.3 5.2 3.0 1 1 2 3 3 3 0 Intermediate filament protein WD40 PF00400.32 ORY53078.1 - 3.8e-06 27.5 1.3 0.00018 22.3 0.1 3.4 4 0 0 4 4 4 1 WD domain, G-beta repeat Ribosomal_L1 PF00687.21 ORY53080.1 - 2.5e-46 158.0 2.8 4.6e-46 157.1 2.5 1.7 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family NUDE_C PF04880.13 ORY53080.1 - 0.37 11.2 3.2 1 9.9 3.2 1.7 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region ETF_alpha PF00766.19 ORY53081.1 - 3.1e-35 120.0 0.8 3.1e-35 120.0 0.8 2.3 2 1 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 ORY53081.1 - 1.7e-27 96.5 9.9 3.2e-22 79.3 7.0 3.1 1 1 1 2 2 2 2 Electron transfer flavoprotein domain V-SNARE_C PF12352.8 ORY53082.1 - 0.001 19.3 0.7 0.001 19.3 0.7 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus SNARE PF05739.19 ORY53082.1 - 0.0018 18.3 0.0 0.0038 17.2 0.0 1.6 1 0 0 1 1 1 1 SNARE domain V-SNARE PF05008.15 ORY53082.1 - 0.0026 18.1 1.9 0.0051 17.2 0.5 2.2 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.13 ORY53082.1 - 0.0061 16.4 2.3 0.011 15.7 0.3 2.3 2 1 1 3 3 3 1 Sec20 ING PF12998.7 ORY53082.1 - 0.078 13.6 3.5 0.98 10.0 0.2 2.9 2 1 1 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Cor1 PF04803.12 ORY53082.1 - 0.14 12.4 5.0 0.14 12.3 1.8 2.2 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region DUF3802 PF12290.8 ORY53082.1 - 1.8 9.1 6.2 2.9 8.4 0.3 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3802) DUF16 PF01519.16 ORY53082.1 - 5.8 7.5 11.2 1.2 9.6 4.8 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF16 Arm PF00514.23 ORY53083.1 - 0.0015 18.5 3.2 0.44 10.7 0.0 3.5 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 ORY53083.1 - 0.013 15.7 1.0 0.86 10.0 0.0 3.1 3 1 0 3 3 3 0 HEAT repeat HEAT_2 PF13646.6 ORY53083.1 - 0.069 13.6 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 HEAT repeats Arm PF00514.23 ORY53084.1 - 0.011 15.7 0.7 9 6.5 0.0 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Tropomyosin PF00261.20 ORY53085.1 - 0.016 14.6 0.1 0.023 14.1 0.1 1.2 1 0 0 1 1 1 0 Tropomyosin EF-hand_4 PF12763.7 ORY53085.1 - 0.039 13.9 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand UQ_con PF00179.26 ORY53086.1 - 1.9e-25 89.2 0.2 2e-25 89.0 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 ORY53086.1 - 0.0087 15.7 0.0 0.0089 15.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 ORY53086.1 - 0.038 14.3 0.0 0.038 14.3 0.0 1.1 1 0 0 1 1 1 0 RWD domain Prok-E2_E PF14462.6 ORY53086.1 - 0.063 13.1 0.0 0.07 12.9 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family E Prok-E2_B PF14461.6 ORY53086.1 - 0.13 11.9 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B Acyltransferase PF01553.21 ORY53087.1 - 1.7e-08 34.1 0.1 3.6e-08 33.1 0.1 1.6 1 0 0 1 1 1 1 Acyltransferase DUF1752 PF08550.10 ORY53087.1 - 0.00013 21.7 2.2 0.00098 18.9 0.9 2.8 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) Adap_comp_sub PF00928.21 ORY53088.1 - 5.5e-84 281.6 0.1 1.1e-83 280.6 0.0 1.5 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 ORY53088.1 - 1.1e-12 48.1 1.3 1.8e-12 47.4 1.3 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RecU PF03838.14 ORY53088.1 - 0.0034 17.4 0.7 8.4 6.4 0.0 3.7 3 1 1 4 4 4 2 Recombination protein U Longin PF13774.6 ORY53088.1 - 0.085 12.9 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Regulated-SNARE-like domain Nop PF01798.18 ORY53089.1 - 1.8e-48 165.0 5.0 2.6e-18 66.3 0.0 3.9 2 1 2 4 4 4 3 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 ORY53089.1 - 5.7e-39 133.8 1.2 1.1e-38 132.9 1.2 1.4 1 0 0 1 1 1 1 Prp31 C terminal domain PapD-like PF14874.6 ORY53089.1 - 0.052 13.7 0.0 0.087 13.0 0.0 1.3 1 0 0 1 1 1 0 Flagellar-associated PapD-like Sec16_C PF12931.7 ORY53090.1 - 7.3e-82 275.4 0.0 7.3e-82 275.4 0.0 1.9 2 0 0 2 2 2 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 ORY53090.1 - 8.3e-10 39.3 2.0 1.9e-09 38.1 0.1 2.8 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region AMP-binding PF00501.28 ORY53091.1 - 3.9e-48 164.1 0.0 4.9e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 ORY53091.1 - 1.4e-10 40.9 1.5 3.6e-10 39.6 1.5 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 ORY53091.1 - 0.0072 17.3 0.0 0.018 16.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HEAT PF02985.22 ORY53092.1 - 0.00095 19.2 0.8 0.0058 16.8 0.0 2.8 2 1 1 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 ORY53092.1 - 0.22 11.9 0.1 0.22 11.9 0.1 3.0 2 1 0 2 2 2 0 HEAT repeats Ribosomal_S18 PF01084.20 ORY53093.1 - 2.4e-17 62.9 0.0 3.3e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 UCR_UQCRX_QCR9 PF05365.12 ORY53094.1 - 1.5e-18 66.5 0.7 2e-18 66.1 0.7 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like HEAT PF02985.22 ORY53095.1 - 5.2e-15 54.3 9.9 0.00013 21.9 0.0 9.2 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 ORY53095.1 - 3.6e-12 46.5 3.0 0.78 10.2 0.0 7.3 5 3 2 7 7 7 3 HEAT repeats HEAT_EZ PF13513.6 ORY53095.1 - 6.9e-11 42.4 7.1 1.8e-09 37.9 0.0 5.2 5 1 1 6 6 5 1 HEAT-like repeat IBN_N PF03810.19 ORY53095.1 - 7.3e-07 29.0 1.4 3.1e-06 27.0 0.1 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF3385 PF11865.8 ORY53095.1 - 2.6e-05 24.2 5.7 0.29 11.1 1.6 4.8 3 1 2 5 5 5 3 Domain of unknown function (DUF3385) DUF577 PF04510.12 ORY53095.1 - 0.0023 17.9 0.7 0.79 9.6 0.1 3.4 3 1 0 3 3 3 1 Family of unknown function (DUF577) Adaptin_N PF01602.20 ORY53095.1 - 0.0075 14.9 8.0 0.11 11.1 0.0 4.7 3 2 3 7 7 7 1 Adaptin N terminal region RIX1 PF08167.12 ORY53095.1 - 0.0096 15.7 1.1 0.79 9.4 0.2 3.4 4 0 0 4 4 4 1 rRNA processing/ribosome biogenesis Cnd1 PF12717.7 ORY53095.1 - 0.013 15.6 2.2 1.7 8.7 0.0 3.8 2 1 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 ORY53095.1 - 0.014 15.4 15.7 0.039 14.0 0.0 6.8 7 1 1 8 8 8 0 Armadillo/beta-catenin-like repeat DRIM PF07539.12 ORY53095.1 - 0.015 13.7 2.1 0.95 7.7 0.3 2.6 2 1 0 2 2 2 0 Down-regulated in metastasis TrpP PF17099.5 ORY53095.1 - 0.023 14.5 0.0 5.9 6.6 0.0 3.7 4 0 0 4 4 4 0 Tryptophan transporter TrpP Vac14_Fab1_bd PF12755.7 ORY53095.1 - 0.037 14.6 0.5 2.8 8.6 0.1 4.2 4 2 1 5 5 5 0 Vacuolar 14 Fab1-binding region U3snoRNP10 PF12397.8 ORY53095.1 - 2.9 8.3 6.4 1.5e+02 2.8 0.0 5.0 6 0 0 6 6 6 0 U3 small nucleolar RNA-associated protein 10 UPF0016 PF01169.19 ORY53096.1 - 1.4e-41 140.7 22.2 5.8e-21 74.6 8.8 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 ORY53096.1 - 7.7e-05 22.5 6.0 0.00058 19.6 0.1 2.4 2 0 0 2 2 2 2 Putative manganese efflux pump TerC PF03741.16 ORY53096.1 - 2.5 7.7 14.9 0.021 14.5 5.1 2.3 2 1 0 2 2 2 0 Integral membrane protein TerC family Methyltransf_23 PF13489.6 ORY53097.1 - 4.2e-15 56.0 0.0 6.5e-15 55.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 ORY53097.1 - 9.5e-13 48.7 0.0 8.6e-12 45.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY53097.1 - 2e-10 41.3 0.0 1.3e-09 38.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 ORY53097.1 - 1.3e-09 38.6 0.0 4.1e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 ORY53097.1 - 1e-06 28.7 0.0 5.8e-06 26.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 ORY53097.1 - 0.00048 19.5 0.0 0.0054 16.1 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 ORY53097.1 - 0.014 14.6 0.0 0.04 13.1 0.0 1.7 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_8 PF05148.15 ORY53097.1 - 0.016 15.1 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase MTS PF05175.14 ORY53097.1 - 0.025 14.1 0.0 0.09 12.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Met_10 PF02475.16 ORY53097.1 - 0.038 13.7 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein CMAS PF02353.20 ORY53097.1 - 0.049 12.9 0.0 0.63 9.3 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase TPMT PF05724.11 ORY53097.1 - 0.049 13.3 0.0 0.75 9.4 0.1 2.0 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Complex1_51K PF01512.17 ORY53098.1 - 5.7e-50 169.1 0.0 8.4e-50 168.6 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 ORY53098.1 - 8.8e-31 105.8 0.1 1.9e-30 104.8 0.1 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 ORY53098.1 - 1.8e-05 24.5 0.0 3.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 SLBB domain CSD PF00313.22 ORY53099.1 - 2e-21 75.6 0.1 3.6e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 ORY53099.1 - 0.12 12.1 0.2 0.65 9.7 0.1 2.2 2 0 0 2 2 2 0 Ribonuclease B OB domain WD40 PF00400.32 ORY53100.1 - 5.2e-15 55.6 2.6 0.058 14.3 0.0 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY53100.1 - 5.1e-11 42.7 0.0 0.6 10.4 0.0 5.4 2 1 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 ORY53100.1 - 5.7e-07 28.4 0.0 9.3e-06 24.4 0.0 2.1 1 1 1 2 2 2 1 Cytochrome D1 heme domain MMS1_N PF10433.9 ORY53100.1 - 0.12 11.0 0.1 2.6 6.6 0.0 2.6 1 1 2 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF2052 PF09747.9 ORY53101.1 - 0.0093 16.1 0.5 0.0093 16.1 0.5 1.8 1 1 1 2 2 2 1 Coiled-coil domain containing protein (DUF2052) DUF1640 PF07798.11 ORY53101.1 - 0.02 14.9 2.1 0.02 14.9 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) DUF5643 PF18705.1 ORY53101.1 - 0.024 14.6 0.1 0.04 13.9 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5643) Uso1_p115_C PF04871.13 ORY53101.1 - 0.33 11.3 11.5 0.11 12.9 8.0 2.0 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4407 PF14362.6 ORY53101.1 - 0.81 9.0 5.2 0.94 8.8 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA PF00004.29 ORY53102.1 - 2.3e-10 41.0 0.0 9.5e-10 39.0 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY53102.1 - 1.8e-06 28.0 0.0 7.4e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY53102.1 - 0.00012 22.5 0.0 0.00038 20.9 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 ORY53102.1 - 0.00013 22.2 0.1 0.00051 20.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 ORY53102.1 - 0.0024 17.3 0.1 0.0072 15.7 0.1 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 ORY53102.1 - 0.005 17.0 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 ORY53102.1 - 0.02 14.6 0.0 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 ORY53102.1 - 0.021 14.5 0.0 0.057 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 ORY53102.1 - 0.06 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORY53102.1 - 0.089 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 ORY53102.1 - 0.12 12.8 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 ORY53102.1 - 0.12 12.9 0.0 0.25 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 ORY53102.1 - 0.15 11.2 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Hydrolase_4 PF12146.8 ORY53103.1 - 0.021 14.1 0.0 0.024 13.9 0.0 1.0 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PhoPQ_related PF10142.9 ORY53103.1 - 0.041 12.5 0.0 0.041 12.5 0.0 1.0 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Mito_carr PF00153.27 ORY53104.1 - 1.9e-55 184.8 7.3 4e-23 81.2 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY53104.1 - 0.0059 15.8 1.5 0.13 11.4 0.1 2.6 2 1 1 3 3 3 2 Gammaproteobacterial serine protease WD40 PF00400.32 ORY53105.1 - 9.9e-24 83.2 8.3 1.6e-07 31.8 0.1 5.3 4 1 1 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY53105.1 - 7.1e-11 42.3 0.0 0.00065 19.9 0.0 4.1 3 2 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 ORY53105.1 - 0.0036 16.0 0.3 0.008 14.9 0.1 1.5 1 1 0 1 1 1 1 Nucleoporin Nup120/160 EMP70 PF02990.16 ORY53106.1 - 7.6e-187 622.1 40.2 7.6e-187 622.1 40.2 1.9 2 1 0 2 2 2 1 Endomembrane protein 70 DPCD PF14913.6 ORY53107.1 - 3.2e-59 199.5 1.6 4.2e-59 199.1 1.6 1.0 1 0 0 1 1 1 1 DPCD protein family KH_7 PF17214.3 ORY53107.1 - 0.0015 18.4 0.0 0.0039 17.1 0.0 1.7 1 0 0 1 1 1 1 KH domain DAHP_synth_2 PF01474.16 ORY53108.1 - 1.8e-199 662.8 0.0 2e-199 662.6 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Chibby PF14645.6 ORY53109.1 - 1.1e-15 58.1 0.3 1.1e-15 58.0 0.3 1.1 1 0 0 1 1 1 1 Chibby family TSC22 PF01166.18 ORY53109.1 - 0.0035 17.6 0.1 0.0063 16.8 0.1 1.6 1 0 0 1 1 1 1 TSC-22/dip/bun family Casc1_N PF15927.5 ORY53110.1 - 8e-36 123.6 6.4 1.2e-35 123.0 6.4 1.3 1 0 0 1 1 1 1 Cancer susceptibility candidate 1 N-terminus DUF148 PF02520.17 ORY53110.1 - 0.24 11.5 4.7 17 5.5 2.3 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF148 Mito_carr PF00153.27 ORY53111.1 - 5.7e-64 212.1 2.9 3e-24 84.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 ORY53111.1 - 0.031 13.4 0.4 5.8 6.0 0.0 2.7 3 0 0 3 3 3 0 Gammaproteobacterial serine protease DUF3147 PF11345.8 ORY53111.1 - 0.055 13.8 0.1 1.5 9.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3147) Spo12 PF05032.12 ORY53113.1 - 1.1e-09 38.0 2.1 2.6e-09 36.8 2.1 1.7 1 0 0 1 1 1 1 Spo12 family Spt20 PF12090.8 ORY53113.1 - 0.35 10.5 7.5 0.4 10.3 7.5 1.2 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 ORY53113.1 - 1.8 7.6 4.1 1.8 7.6 4.1 1.0 1 0 0 1 1 1 0 Drosophila roughex protein SNF2_N PF00176.23 ORY53114.1 - 7.7e-58 195.9 0.0 1.2e-57 195.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY53114.1 - 3.2e-15 56.4 0.0 1.7e-14 54.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY53114.1 - 2.3e-11 44.0 0.0 3.8e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Rad54_N PF08658.10 ORY53114.1 - 0.00041 20.6 0.0 0.0023 18.1 0.0 2.1 2 0 0 2 2 2 1 Rad54 N terminal SWI2_SNF2 PF18766.1 ORY53114.1 - 0.00061 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase TSNAXIP1_N PF15739.5 ORY53115.1 - 3.2e-12 46.8 3.3 3.2e-12 46.8 3.3 2.7 2 0 0 2 2 2 1 Translin-associated factor X-interacting N-terminus Bacillus_HBL PF05791.11 ORY53115.1 - 0.021 14.7 0.7 0.021 14.7 0.7 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TSC22 PF01166.18 ORY53115.1 - 0.024 15.0 5.3 2.6 8.4 0.1 3.5 2 1 1 3 3 3 0 TSC-22/dip/bun family PhoU PF01895.19 ORY53115.1 - 0.15 12.6 6.6 0.36 11.3 0.3 3.3 2 1 1 3 3 3 0 PhoU domain Rsbr_N PF08678.10 ORY53115.1 - 0.25 11.4 5.4 0.88 9.7 0.1 3.3 3 1 0 3 3 3 0 Rsbr N terminal Cep57_CLD_2 PF14197.6 ORY53115.1 - 0.32 11.1 3.6 15 5.8 0.1 3.4 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 CHDCT2 PF08074.11 ORY53115.1 - 0.73 10.0 5.8 0.3 11.2 1.2 2.6 2 2 0 2 2 2 0 CHDCT2 (NUC038) domain CLZ PF16526.5 ORY53115.1 - 0.78 10.1 4.0 1.4 9.4 1.1 2.8 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ZapB PF06005.12 ORY53115.1 - 1.7 9.2 10.1 0.93 10.0 1.7 3.5 4 1 0 4 4 3 0 Cell division protein ZapB Seryl_tRNA_N PF02403.22 ORY53115.1 - 2.5 8.4 11.1 0.21 11.8 1.3 3.3 2 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Med21 PF11221.8 ORY53115.1 - 2.9 8.1 8.9 0.97 9.7 2.1 2.7 3 0 0 3 3 3 0 Subunit 21 of Mediator complex Jnk-SapK_ap_N PF09744.9 ORY53115.1 - 5.7 7.1 14.5 0.13 12.5 4.9 2.8 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 ANAPC4_WD40 PF12894.7 ORY53116.1 - 1.3e-13 51.1 0.1 0.0076 16.5 0.0 6.5 3 1 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 ORY53116.1 - 6.6e-13 48.9 10.8 1.1e-05 26.1 0.0 6.7 7 1 0 7 7 6 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 ORY53116.1 - 8.6e-07 28.3 5.4 1.2 8.1 0.0 5.0 3 1 2 5 5 5 4 Coatomer WD associated region ANAPC3 PF12895.7 ORY53116.1 - 0.00069 19.8 0.1 1.6 9.0 0.0 3.4 1 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 ORY53116.1 - 0.0065 16.4 3.2 30 5.0 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40_like PF17005.5 ORY53116.1 - 0.0076 15.6 0.8 5.8 6.1 0.0 3.7 2 2 3 5 5 5 1 WD40-like domain Clathrin PF00637.20 ORY53116.1 - 0.019 14.9 6.0 2 8.3 0.2 3.6 3 1 0 3 3 3 0 Region in Clathrin and VPS TPR_14 PF13428.6 ORY53116.1 - 0.027 15.3 2.7 5.3 8.1 0.1 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 ORY53116.1 - 0.037 14.1 1.4 11 6.4 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40_3 PF15911.5 ORY53116.1 - 0.13 12.3 0.0 1.8 8.6 0.0 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat ADD_DNMT3 PF17980.1 ORY53116.1 - 0.15 12.0 2.5 0.71 9.9 0.2 2.6 2 0 0 2 2 2 0 Cysteine rich ADD domain in DNMT3 TPR_12 PF13424.6 ORY53116.1 - 0.33 11.3 3.4 35 4.8 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 ORY53116.1 - 0.57 10.9 5.1 2.6 8.9 0.3 3.9 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 ORY53116.1 - 0.76 10.3 2.7 14 6.2 0.0 3.8 3 1 0 4 4 4 0 Tetratricopeptide repeat zinc_ribbon_9 PF14369.6 ORY53116.1 - 8.5 6.7 10.0 12 6.3 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon muHD PF10291.9 ORY53117.1 - 9e-30 104.0 0.0 1.1e-27 97.1 0.0 2.5 3 0 0 3 3 3 2 Muniscin C-terminal mu homology domain MRG PF05712.13 ORY53118.1 - 9.1e-56 188.3 7.0 1.5e-55 187.6 7.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 ORY53118.1 - 3.9e-11 42.7 0.1 8.4e-11 41.6 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 ORY53118.1 - 0.00036 20.4 0.2 0.0014 18.5 0.2 2.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ribosomal_60s PF00428.19 ORY53118.1 - 0.034 14.7 1.9 0.084 13.5 1.9 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein LRR_4 PF12799.7 ORY53119.1 - 1.6e-36 123.7 62.9 3.3e-06 27.3 0.1 11.8 6 2 4 12 12 12 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY53119.1 - 8.7e-32 108.7 62.8 1.7e-06 27.7 3.1 10.8 4 3 4 10 10 10 10 Leucine rich repeat LRR_1 PF00560.33 ORY53119.1 - 1e-16 58.9 34.6 0.77 10.5 0.1 16.9 17 1 0 17 17 17 6 Leucine Rich Repeat LRR_6 PF13516.6 ORY53119.1 - 0.00059 19.7 59.1 0.38 10.9 0.2 14.4 17 0 0 17 17 17 5 Leucine Rich repeat LRR_2 PF07723.13 ORY53119.1 - 0.0019 18.8 2.5 88 4.0 0.0 6.6 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_5 PF13306.6 ORY53119.1 - 0.0046 16.9 0.3 0.047 13.7 0.0 2.8 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) BRO1 PF03097.18 ORY53120.1 - 9.5e-32 110.2 0.1 2.4e-30 105.7 0.0 2.0 2 0 0 2 2 2 2 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 ORY53120.1 - 8e-08 31.9 0.1 5.3e-07 29.2 0.2 2.1 2 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV Mito_fiss_reg PF05308.11 ORY53120.1 - 4.9 7.2 6.9 0.53 10.3 2.2 1.9 3 0 0 3 3 3 0 Mitochondrial fission regulator ALIX_LYPXL_bnd PF13949.6 ORY53122.1 - 1.5e-13 50.7 0.0 1.9e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF2791 PF10923.8 ORY53122.1 - 0.18 10.6 0.0 0.18 10.6 0.0 1.0 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) p450 PF00067.22 ORY53123.1 - 2.3e-46 158.5 0.1 4.9e-35 121.2 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DUF1690 PF07956.11 ORY53123.1 - 0.026 14.9 0.3 0.06 13.8 0.1 1.6 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) p450 PF00067.22 ORY53124.1 - 1.5e-16 60.3 0.0 6.1e-07 28.5 0.0 3.0 2 1 0 3 3 3 2 Cytochrome P450 MHC_II_beta PF00969.19 ORY53124.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain 5-FTHF_cyc-lig PF01812.20 ORY53127.1 - 2e-33 115.8 0.4 9.2e-20 71.3 0.0 2.0 1 1 1 2 2 2 2 5-formyltetrahydrofolate cyclo-ligase family FolB PF02152.18 ORY53127.1 - 0.084 13.4 0.1 0.14 12.7 0.1 1.3 1 0 0 1 1 1 0 Dihydroneopterin aldolase AAA PF00004.29 ORY53128.1 - 7.3e-45 152.6 0.1 2e-44 151.2 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY53128.1 - 1e-09 38.5 0.1 2.9e-09 37.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 ORY53128.1 - 6.1e-08 33.2 0.3 1.8e-05 25.2 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.14 ORY53128.1 - 6.3e-08 32.9 0.0 2.8e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 ORY53128.1 - 3.8e-06 26.2 0.0 7.2e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_lid_3 PF17862.1 ORY53128.1 - 1.5e-05 24.7 0.1 3.7e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain TsaE PF02367.17 ORY53128.1 - 0.00012 22.0 0.1 0.0067 16.4 0.0 2.3 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 ORY53128.1 - 0.00015 22.3 0.0 0.0014 19.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 ORY53128.1 - 0.00023 21.5 3.7 0.014 15.7 1.4 2.8 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 ORY53128.1 - 0.00033 20.5 0.0 0.0009 19.0 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 ORY53128.1 - 0.00041 20.3 0.1 0.0032 17.4 0.0 2.4 3 0 0 3 3 3 1 NTPase AAA_28 PF13521.6 ORY53128.1 - 0.00044 20.5 0.1 0.0011 19.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.22 ORY53128.1 - 0.00096 19.5 0.0 0.002 18.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 ORY53128.1 - 0.0014 18.6 0.0 0.0041 17.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY53128.1 - 0.002 17.9 0.1 0.0051 16.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 ORY53128.1 - 0.0028 17.2 0.1 0.019 14.5 0.1 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 ORY53128.1 - 0.0042 17.2 0.0 0.009 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 ORY53128.1 - 0.0044 16.3 0.0 0.0092 15.2 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain TniB PF05621.11 ORY53128.1 - 0.005 16.3 0.0 0.56 9.6 0.0 2.5 2 0 0 2 2 2 1 Bacterial TniB protein AAA_3 PF07726.11 ORY53128.1 - 0.0061 16.4 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 ORY53128.1 - 0.0069 15.8 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 ORY53128.1 - 0.0094 15.9 0.1 0.066 13.1 0.0 2.2 2 0 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.17 ORY53128.1 - 0.0094 15.7 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 ORY53128.1 - 0.0095 15.5 0.5 0.046 13.3 0.1 2.0 1 1 0 2 2 2 1 AAA domain ATPase PF06745.13 ORY53128.1 - 0.015 14.6 0.6 0.39 10.0 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_24 PF13479.6 ORY53128.1 - 0.018 14.8 0.1 0.04 13.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 ORY53128.1 - 0.028 14.2 0.1 0.085 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 ORY53128.1 - 0.035 14.4 0.2 0.11 12.9 0.2 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 ORY53128.1 - 0.039 13.7 0.2 0.9 9.2 0.0 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.22 ORY53128.1 - 0.044 13.0 0.0 1 8.5 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Bac_DnaA PF00308.18 ORY53128.1 - 0.052 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial dnaA protein ATPase_2 PF01637.18 ORY53128.1 - 0.074 13.0 0.1 0.56 10.1 0.1 2.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 ORY53128.1 - 0.11 11.6 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_29 PF13555.6 ORY53128.1 - 0.19 11.5 0.0 0.4 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Nas2_N PF18265.1 ORY53129.1 - 2.8e-28 97.6 0.3 3.6e-28 97.3 0.3 1.1 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 ORY53129.1 - 1.5e-06 27.9 0.8 8.6e-06 25.5 0.8 2.3 2 1 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 ORY53129.1 - 2.4e-06 27.8 0.7 6e-06 26.5 0.2 1.9 2 1 0 2 2 2 1 PDZ domain PDZ PF00595.24 ORY53129.1 - 0.00075 19.8 0.1 0.0018 18.5 0.1 1.7 1 1 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 ORY53129.1 - 0.18 12.2 0.2 2.5 8.4 0.2 2.2 1 1 0 1 1 1 0 GRASP55/65 PDZ-like domain LRR_4 PF12799.7 ORY53130.1 - 7.6e-15 54.8 10.9 4.4e-06 26.9 0.7 5.4 2 2 5 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 ORY53130.1 - 1.3e-08 34.4 10.5 0.0082 15.9 0.2 4.2 1 1 4 5 5 5 5 Leucine rich repeat LRR_6 PF13516.6 ORY53130.1 - 0.001 19.0 6.6 2.7 8.3 0.0 4.4 5 0 0 5 5 5 2 Leucine Rich repeat PIN_2 PF10130.9 ORY53130.1 - 0.0048 17.1 0.2 0.019 15.2 0.2 2.0 1 1 1 2 2 2 1 PIN domain PPIP5K2_N PF18086.1 ORY53130.1 - 0.093 12.9 0.1 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain LRR_9 PF14580.6 ORY53130.1 - 0.16 11.5 4.7 0.99 8.9 0.3 2.3 1 1 0 2 2 2 0 Leucine-rich repeat LRR_1 PF00560.33 ORY53130.1 - 1.4 9.8 9.0 31 5.7 0.0 4.7 4 1 0 4 4 4 0 Leucine Rich Repeat DUF2870 PF11069.8 ORY53131.1 - 8.5e-40 135.1 0.8 8.5e-40 135.1 0.8 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2870) Sybindin PF04099.12 ORY53132.1 - 2.6e-53 179.8 0.1 2.9e-53 179.6 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 ORY53132.1 - 2e-09 37.7 0.0 2.2e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF5612 PF18462.1 ORY53132.1 - 0.018 14.8 0.0 0.024 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5612) Dpy-30 PF05186.13 ORY53133.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Dpy-30 motif Leu_zip PF15294.6 ORY53134.1 - 3.9e-27 95.5 13.1 7.5e-22 78.1 2.9 2.0 1 1 1 2 2 2 2 Leucine zipper DUF2121 PF09894.9 ORY53134.1 - 0.014 15.0 0.3 0.046 13.3 0.0 2.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2121) zf-met PF12874.7 ORY53134.1 - 0.024 15.0 0.1 0.043 14.2 0.1 1.4 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DUF5448 PF17526.2 ORY53134.1 - 0.025 14.7 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5448) Dsl1_N PF11988.8 ORY53134.1 - 0.048 12.6 0.1 0.048 12.6 0.1 1.6 2 1 0 1 1 1 0 Retrograde transport protein Dsl1 N terminal DUF948 PF06103.11 ORY53134.1 - 0.057 13.7 0.8 9.4 6.6 0.0 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) CENP-F_leu_zip PF10473.9 ORY53134.1 - 0.091 12.8 6.8 0.04 13.9 3.4 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PKcGMP_CC PF16808.5 ORY53134.1 - 0.26 11.1 0.3 0.26 11.1 0.3 4.2 5 0 0 5 5 5 0 Coiled-coil N-terminus of cGMP-dependent protein kinase RNase_PH PF01138.21 ORY53135.1 - 1.4e-25 90.3 0.1 3.8e-25 88.9 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 ORY53135.1 - 3.4e-14 52.6 0.0 6.1e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Peptidase_S24 PF00717.23 ORY53135.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Peptidase S24-like DUF21 PF01595.20 ORY53136.1 - 4.2e-39 134.0 0.2 7.4e-39 133.2 0.2 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 ORY53136.1 - 0.00022 21.6 4.4 3.3 8.2 0.0 4.0 4 0 0 4 4 4 3 CBS domain Band_7 PF01145.25 ORY53138.1 - 8.6e-11 42.2 0.0 1.7e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 ORY53138.1 - 0.072 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 SPFH domain-Band 7 family Band_7 PF01145.25 ORY53139.1 - 3.6e-28 98.8 1.5 3.6e-28 98.8 1.5 1.7 1 1 1 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 ORY53139.1 - 1.9e-25 88.7 1.0 1.9e-25 88.7 1.0 2.0 2 0 0 2 2 2 1 C-terminal region of band_7 Pkinase PF00069.25 ORY53140.1 - 4.2e-53 180.4 0.0 9.7e-53 179.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY53140.1 - 1.7e-39 135.7 0.0 2.2e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 ORY53140.1 - 3.9e-05 22.8 1.1 0.0032 16.5 1.1 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 ORY53140.1 - 0.00056 18.8 0.0 0.00095 18.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 ORY53140.1 - 0.013 15.4 0.0 0.032 14.2 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 ORY53140.1 - 0.018 14.6 0.1 0.05 13.2 0.0 1.6 1 1 1 2 2 2 0 RIO1 family Kinase-like PF14531.6 ORY53140.1 - 0.029 13.7 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like ABC1 PF03109.16 ORY53140.1 - 0.081 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Seadorna_VP7 PF07387.11 ORY53140.1 - 0.093 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Epimerase PF01370.21 ORY53142.1 - 8.6e-06 25.4 0.1 0.00041 19.9 0.1 2.4 1 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 ORY53142.1 - 0.00024 21.1 0.2 0.27 11.1 0.0 2.7 2 1 1 3 3 3 2 NAD(P)H-binding NmrA PF05368.13 ORY53142.1 - 0.03 13.9 0.1 0.8 9.2 0.1 2.2 1 1 1 2 2 2 0 NmrA-like family 3Beta_HSD PF01073.19 ORY53142.1 - 0.045 12.7 0.4 0.61 9.0 0.1 2.5 2 1 1 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family DnaJ-X PF14308.6 ORY53144.1 - 1.8e-39 135.4 6.2 3.4e-39 134.5 6.2 1.4 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 ORY53144.1 - 5.3e-23 80.9 0.5 1.5e-22 79.5 0.5 1.8 1 0 0 1 1 1 1 DnaJ domain ATG_C PF09333.11 ORY53144.1 - 0.00021 21.5 1.1 0.0012 19.1 0.1 2.7 2 1 1 3 3 3 1 Autophagy-related protein C terminal domain p450 PF00067.22 ORY53145.1 - 1.3e-66 225.3 0.0 1.5e-66 225.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 EPSP_synthase PF00275.20 ORY53146.1 - 1.8e-122 409.1 0.0 2.9e-122 408.4 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 ORY53146.1 - 1.9e-101 338.6 0.2 3.3e-101 337.9 0.2 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 ORY53146.1 - 1.7e-42 146.2 0.0 4.6e-42 144.8 0.0 1.7 1 1 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 ORY53146.1 - 2.1e-35 122.2 0.0 1.9e-33 115.8 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 ORY53146.1 - 1.6e-20 73.1 0.1 5e-20 71.6 0.1 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 ORY53146.1 - 1.3e-09 37.7 0.0 3e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 ORY53146.1 - 1.2e-05 25.2 0.2 3.4e-05 23.7 0.2 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 ORY53146.1 - 5.5e-05 23.2 0.1 0.00018 21.6 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AAA_18 PF13238.6 ORY53146.1 - 0.032 14.8 0.0 0.11 13.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 ORY53146.1 - 0.045 13.9 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY53146.1 - 0.11 12.8 0.0 0.37 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain PTPRCAP PF15713.5 ORY53146.1 - 0.13 12.5 0.1 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated HK PF02110.15 ORY53147.1 - 2e-66 223.9 2.6 2e-66 223.9 2.6 1.8 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 ORY53147.1 - 4e-59 199.0 1.2 7.9e-59 198.0 1.2 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase Carb_kinase PF01256.17 ORY53147.1 - 3e-06 26.9 1.1 5e-06 26.2 1.1 1.3 1 0 0 1 1 1 1 Carbohydrate kinase SepSecS PF05889.13 ORY53147.1 - 0.019 13.6 0.2 1.7 7.2 0.0 2.2 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Sugar_tr PF00083.24 ORY53148.1 - 1.4e-38 133.0 33.2 1.9e-26 93.0 12.6 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY53148.1 - 3.8e-26 91.9 46.3 5.1e-26 91.4 42.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 ORY53149.1 - 8.9e-16 58.0 9.4 0.023 15.6 0.0 7.5 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY53149.1 - 6.4e-06 26.4 0.0 0.48 10.8 0.0 3.7 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain GDP_Man_Dehyd PF16363.5 ORY53150.1 - 4e-48 164.5 0.0 2.7e-47 161.8 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY53150.1 - 4.2e-35 121.4 0.0 4.8e-35 121.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ORY53150.1 - 1.7e-06 27.4 0.0 2.6e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 ORY53150.1 - 7.9e-06 25.2 0.0 0.0065 15.7 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein ubiquitin PF00240.23 ORY53151.1 - 3e-10 39.7 0.0 4.8e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 ORY53151.1 - 5.3e-10 39.0 0.2 1.6e-09 37.5 0.2 1.8 1 0 0 1 1 1 1 UBA/TS-N domain STI1 PF17830.1 ORY53151.1 - 8.3e-06 25.6 25.0 8.3e-05 22.4 9.7 3.1 2 1 1 3 3 3 2 STI1 domain CUE PF02845.16 ORY53151.1 - 0.01 15.5 0.0 0.026 14.2 0.0 1.7 1 0 0 1 1 1 0 CUE domain Rad60-SLD PF11976.8 ORY53151.1 - 0.012 15.4 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 ORY53151.1 - 0.028 14.9 0.0 0.096 13.2 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 ORY53151.1 - 0.047 13.8 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like GerD PF17898.1 ORY53151.1 - 1.2 9.1 8.5 0.15 12.1 1.3 2.2 1 1 1 2 2 2 0 Spore germination GerD central core domain Avl9 PF09794.9 ORY53152.1 - 5.7e-118 393.9 0.0 7.5e-118 393.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 ORY53152.1 - 1.2e-07 31.6 0.0 0.0035 17.3 0.0 2.7 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 ORY53152.1 - 2.1e-07 30.8 0.4 0.022 14.3 0.0 2.6 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2347) DENN PF02141.21 ORY53152.1 - 0.00014 21.8 0.4 0.018 15.0 0.1 2.6 2 1 0 2 2 2 1 DENN (AEX-3) domain PRP4 PF08799.11 ORY53152.1 - 0.0034 16.9 0.5 0.0083 15.7 0.5 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Apo-CIII PF05778.12 ORY53152.1 - 6.6 6.4 10.9 5.1 6.8 3.6 2.5 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) Myosin_head PF00063.21 ORY53153.1 - 3.8e-243 808.7 1.6 5.1e-243 808.2 1.6 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 ORY53153.1 - 3.3e-46 157.3 3.6 5.7e-46 156.6 3.6 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_9 PF14604.6 ORY53153.1 - 3.3e-18 65.3 0.1 6.6e-18 64.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY53153.1 - 1.6e-17 62.8 0.1 3.2e-17 61.9 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY53153.1 - 8.5e-12 44.6 0.0 1.8e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.6 ORY53153.1 - 0.0035 17.6 0.0 0.13 12.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain IQ PF00612.27 ORY53153.1 - 0.012 15.3 2.4 0.027 14.3 2.4 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif AAA_16 PF13191.6 ORY53153.1 - 0.027 14.9 0.0 0.072 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 ORY53153.1 - 0.068 12.4 0.0 0.33 10.2 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.26 ORY53153.1 - 0.077 12.7 0.1 0.75 9.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.27 ORY53153.1 - 0.25 11.9 1.8 0.83 10.2 0.1 2.5 2 0 0 2 2 2 0 ABC transporter DUF1460 PF07313.12 ORY53154.1 - 0.06 12.7 0.0 0.093 12.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1460) GATA PF00320.27 ORY53155.1 - 4.5e-11 42.1 3.3 1e-10 41.0 3.3 1.6 1 0 0 1 1 1 1 GATA zinc finger Zn-ribbon_8 PF09723.10 ORY53155.1 - 0.019 15.0 0.3 0.039 14.1 0.3 1.4 1 0 0 1 1 1 0 Zinc ribbon domain zf-C2HE PF16278.5 ORY53155.1 - 0.11 13.0 3.1 0.38 11.2 0.1 2.6 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger TF_Zn_Ribbon PF08271.12 ORY53155.1 - 0.12 11.9 0.3 0.24 10.9 0.3 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 ORY53155.1 - 0.14 12.1 0.9 0.28 11.1 0.9 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain PriA_CRR PF18319.1 ORY53155.1 - 0.16 12.0 1.7 3.2 7.8 0.1 2.4 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain Nudix_N_2 PF14803.6 ORY53155.1 - 9.9 6.2 6.0 7.4 6.6 2.6 2.5 2 1 1 3 3 3 0 Nudix N-terminal Per1 PF04080.13 ORY53156.1 - 2.7e-91 305.9 13.3 3.2e-91 305.6 13.3 1.1 1 0 0 1 1 1 1 Per1-like family Prenyltrans PF00432.21 ORY53158.1 - 3.2e-32 110.0 6.9 1.6e-13 50.1 0.2 5.6 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat PARG_cat PF05028.14 ORY53159.1 - 5.7e-34 117.9 0.2 1.3e-17 64.1 0.1 2.1 1 1 1 2 2 2 2 Poly (ADP-ribose) glycohydrolase (PARG) TFIID-18kDa PF02269.16 ORY53159.1 - 0.02 14.9 0.0 0.068 13.2 0.0 1.7 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit ACOX PF01756.19 ORY53160.1 - 9.7e-16 57.8 0.0 1.9e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 ORY53160.1 - 5.4e-14 52.2 0.0 1.1e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 ORY53160.1 - 4e-07 30.4 0.0 1.1e-06 28.9 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain WD40 PF00400.32 ORY53161.1 - 1.1e-15 57.7 7.1 0.024 15.5 0.0 6.8 6 0 0 6 6 6 3 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 ORY53161.1 - 3.2e-10 39.7 11.3 7.9e-10 38.4 11.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY53161.1 - 1.4e-07 31.2 12.3 3.9e-07 29.8 12.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY53161.1 - 2.3e-07 30.7 10.6 3e-07 30.4 8.5 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 ORY53161.1 - 9.2e-07 29.1 10.2 9.2e-07 29.1 10.2 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 ORY53161.1 - 1.3e-06 28.1 8.4 3.3e-06 26.8 8.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ANAPC4_WD40 PF12894.7 ORY53161.1 - 2.3e-05 24.6 4.7 0.16 12.3 0.5 4.8 4 2 2 6 6 5 1 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_5 PF14634.6 ORY53161.1 - 3.5e-05 23.7 9.7 9.4e-05 22.3 9.7 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 ORY53161.1 - 3.6e-05 23.8 12.0 0.00073 19.6 11.4 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING WD40_like PF17005.5 ORY53161.1 - 0.0022 17.4 0.0 0.014 14.7 0.0 2.2 1 1 1 2 2 2 1 WD40-like domain Prok-RING_4 PF14447.6 ORY53161.1 - 0.012 15.5 7.3 0.031 14.1 7.3 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 eIF2A PF08662.11 ORY53161.1 - 0.042 13.7 0.5 0.85 9.5 0.3 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A zf-RING_10 PF16685.5 ORY53161.1 - 0.065 13.4 4.4 0.14 12.3 4.4 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 ORY53161.1 - 0.32 11.3 9.9 0.22 11.9 7.2 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 ORY53161.1 - 1.3 8.8 6.6 3.4 7.5 6.6 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 ORY53161.1 - 2.3 8.2 4.5 4.5 7.2 4.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 ORY53161.1 - 2.9 7.7 9.7 2.3 8.0 7.7 2.0 2 0 0 2 2 2 0 RING-like zinc finger PHD PF00628.29 ORY53162.1 - 0.004 17.0 10.8 0.0079 16.1 10.8 1.5 1 0 0 1 1 1 1 PHD-finger BppL_N PF18338.1 ORY53162.1 - 0.12 12.1 0.5 0.27 11.1 0.5 1.5 1 0 0 1 1 1 0 Lower baseplate protein N-terminal domain zf-AN1 PF01428.16 ORY53162.1 - 0.6 10.3 7.8 0.24 11.6 5.0 1.9 1 1 0 1 1 1 0 AN1-like Zinc finger IBR PF01485.21 ORY53162.1 - 1.4 9.2 12.9 0.2 11.9 6.8 2.4 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain PKD_channel PF08016.12 ORY53163.1 - 1.2e-08 34.1 3.7 1.8e-08 33.5 3.7 1.2 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 ORY53163.1 - 4.2e-07 29.5 3.4 6.1e-07 28.9 3.4 1.3 1 0 0 1 1 1 1 Ion transport protein Ank_3 PF13606.6 ORY53165.1 - 3.3e-06 27.0 0.2 0.057 14.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 ORY53165.1 - 3.6e-06 27.5 0.1 0.064 13.8 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 ORY53165.1 - 0.00035 20.9 0.1 0.5 10.9 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 ORY53165.1 - 0.0013 19.2 0.0 2.9 8.6 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 ORY53165.1 - 0.004 17.4 0.0 1.1 9.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) N6-adenineMlase PF10237.9 ORY53166.1 - 3.4e-53 179.7 0.0 4e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase SWIRM PF04433.17 ORY53167.1 - 7e-29 100.0 0.0 1.2e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 ORY53167.1 - 1.4e-16 60.2 11.6 1.4e-16 60.2 11.6 1.9 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 ORY53167.1 - 2e-10 40.7 0.0 3.6e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 ORY53167.1 - 2.7e-06 27.5 0.0 5.9e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain APG6_N PF17675.1 ORY53167.1 - 1.2 9.7 5.9 2.2 8.8 5.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region M PF02370.16 ORY53167.1 - 2.3 9.1 7.1 31 5.6 0.1 2.6 2 0 0 2 2 2 0 M protein repeat Sel1 PF08238.12 ORY53168.1 - 4.9e-37 125.5 9.6 1.1e-07 32.2 0.0 7.4 7 0 0 7 7 7 6 Sel1 repeat DUF1932 PF09130.11 ORY53168.1 - 0.0077 16.2 0.0 0.058 13.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1932) TIR_2 PF13676.6 ORY53168.1 - 0.13 12.8 0.1 2.4 8.8 0.0 2.8 3 0 0 3 3 3 0 TIR domain BRCA2 PF00634.18 ORY53168.1 - 0.15 11.8 0.6 0.37 10.5 0.2 1.9 2 0 0 2 2 2 0 BRCA2 repeat Sugar_tr PF00083.24 ORY53169.1 - 7.3e-110 367.9 26.6 1.1e-66 225.6 8.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY53169.1 - 3.1e-23 82.3 40.2 8.6e-14 51.2 17.0 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.16 ORY53169.1 - 0.007 14.6 1.3 0.011 14.0 0.4 1.8 1 1 0 1 1 1 1 BT1 family TIR_2 PF13676.6 ORY53170.1 - 5e-11 43.3 0.1 8e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 TIR domain TIR PF01582.20 ORY53170.1 - 0.027 14.3 0.0 0.046 13.5 0.0 1.3 1 0 0 1 1 1 0 TIR domain DUF5357 PF17310.2 ORY53171.1 - 0.041 12.4 0.3 0.046 12.3 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5357) CCB2_CCB4 PF11152.8 ORY53171.1 - 0.049 12.9 0.9 0.06 12.6 0.9 1.2 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 EMP70 PF02990.16 ORY53171.1 - 0.069 11.8 2.4 0.079 11.6 2.4 1.0 1 0 0 1 1 1 0 Endomembrane protein 70 FAP206 PF12018.8 ORY53172.1 - 3.9e-45 154.5 0.7 2.5e-28 99.4 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function Apolipoprotein PF01442.18 ORY53172.1 - 0.098 12.5 1.0 0.48 10.3 0.7 2.2 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF1878 PF08963.10 ORY53172.1 - 0.31 11.5 1.6 1.5 9.4 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1878) DUF669 PF05037.13 ORY53173.1 - 0.13 12.3 0.1 2.5 8.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF669) Polysacc_deac_1 PF01522.21 ORY53174.1 - 1.2e-19 70.5 0.0 1.8e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Sad1_UNC PF07738.13 ORY53176.1 - 1.3e-16 60.8 0.0 2.2e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Rhomboid_SP PF12595.8 ORY53177.1 - 0.0043 16.5 1.3 0.0078 15.6 1.3 1.4 1 0 0 1 1 1 1 Rhomboid serine protease HSBP1 PF06825.12 ORY53178.1 - 4.3e-11 42.5 1.4 1.9e-09 37.2 0.2 2.1 2 0 0 2 2 2 2 Heat shock factor binding protein 1 Prominin PF05478.11 ORY53178.1 - 0.016 13.2 0.6 0.019 13.0 0.6 1.0 1 0 0 1 1 1 0 Prominin RhoGAP PF00620.27 ORY53179.1 - 9e-23 80.8 0.0 2.6e-22 79.3 0.0 1.8 1 1 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.17 ORY53179.1 - 8.9e-11 42.3 0.1 7.5e-05 23.2 0.0 2.7 2 0 0 2 2 2 2 MyTH4 domain WW PF00397.26 ORY53179.1 - 2.5e-07 30.7 10.7 0.0011 19.1 0.2 2.5 2 0 0 2 2 2 2 WW domain GSIII_N PF12437.8 ORY53180.1 - 1.7e-61 206.5 0.0 2.9e-61 205.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 ORY53180.1 - 1.5e-40 137.7 0.0 2.8e-40 136.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 ORY53180.1 - 1.8e-20 73.3 0.0 3.6e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Tmemb_cc2 PF10267.9 ORY53180.1 - 0.14 11.3 0.3 0.2 10.7 0.3 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Tyrosinase PF00264.20 ORY53181.1 - 1.4e-32 113.8 10.6 3e-17 63.7 0.5 2.6 2 1 1 3 3 3 2 Common central domain of tyrosinase AAA_18 PF13238.6 ORY53183.1 - 0.032 14.8 0.0 0.035 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain FluMu_N PF17891.1 ORY53183.1 - 0.12 12.1 0.0 2.1 8.2 0.0 2.3 2 0 0 2 2 2 0 Mu-like prophage FluMu N-terminal domain Na_trans_assoc PF06512.13 ORY53185.1 - 0.005 17.1 0.7 0.005 17.1 0.7 1.7 1 1 1 2 2 2 1 Sodium ion transport-associated AAA PF00004.29 ORY53186.1 - 9.8e-49 165.2 0.0 6.1e-40 136.7 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 ORY53186.1 - 2.5e-27 94.4 5.4 2.1e-14 53.0 1.0 2.4 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 ORY53186.1 - 6.5e-06 26.0 0.0 8.5e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 ORY53186.1 - 0.00048 20.6 0.0 0.037 14.4 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 ORY53186.1 - 0.00098 19.1 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_2 PF07724.14 ORY53186.1 - 0.002 18.3 0.0 0.0048 17.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 ORY53186.1 - 0.0025 17.8 0.3 0.024 14.6 0.0 2.7 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.10 ORY53186.1 - 0.049 13.6 0.0 0.13 12.2 0.0 1.8 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain ABC_tran PF00005.27 ORY53186.1 - 0.052 14.1 0.0 0.14 12.6 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 ORY53186.1 - 0.17 11.9 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 ORY53186.1 - 0.26 10.8 0.0 0.52 9.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NuA4 PF09340.10 ORY53187.1 - 0.14 12.1 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 NPCC PF08058.11 ORY53187.1 - 4.2 7.4 7.5 3.1 7.9 2.0 2.8 2 0 0 2 2 2 0 Nuclear pore complex component DUF2341 PF10102.9 ORY53189.1 - 0.22 12.1 0.3 0.22 12.1 0.3 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF2341) DUF2423 PF10338.9 ORY53190.1 - 1.7e-11 44.2 0.7 3.5e-11 43.1 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Ldh_1_C PF02866.18 ORY53192.1 - 2.3e-47 161.0 0.8 2.9e-47 160.7 0.2 1.4 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 ORY53192.1 - 1.1e-16 61.2 0.1 1.9e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain GPI-anchored PF10342.9 ORY53193.1 - 0.012 16.4 0.4 0.014 16.1 0.4 1.1 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family EMP24_GP25L PF01105.24 ORY53194.1 - 2.2e-37 128.8 0.8 2.6e-37 128.5 0.8 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DIX PF00778.17 ORY53194.1 - 0.17 11.7 2.5 0.34 10.8 0.2 2.5 1 1 2 3 3 3 0 DIX domain Rib_5-P_isom_A PF06026.14 ORY53195.1 - 3e-51 173.5 0.1 1.3e-50 171.4 0.1 1.8 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) EMP24_GP25L PF01105.24 ORY53196.1 - 4.8e-32 111.4 0.2 5.8e-32 111.1 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PWWP PF00855.17 ORY53197.1 - 4.1e-06 27.1 0.1 8.1e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 PWWP domain RBB1NT PF08169.11 ORY53197.1 - 0.026 14.7 0.0 0.084 13.0 0.0 1.9 1 1 0 1 1 1 0 RBB1NT (NUC162) domain Fcf2 PF08698.11 ORY53198.1 - 1.4e-33 115.1 0.7 4e-33 113.7 0.1 2.1 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing Atypical_Card PF18461.1 ORY53199.1 - 0.076 13.2 0.0 19 5.5 0.0 3.7 3 0 0 3 3 3 0 Atypical caspase recruitment domain YWFCY PF14293.6 ORY53201.1 - 4.2 7.7 6.4 2.6 8.4 0.0 3.7 4 0 0 4 4 4 0 YWFCY protein BCDHK_Adom3 PF10436.9 ORY53202.1 - 1e-39 136.0 0.2 1.8e-39 135.2 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase zf-PARP PF00645.18 ORY53203.1 - 2.9e-13 50.5 0.0 3.1e-12 47.2 0.0 2.3 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-C3HC4_3 PF13920.6 ORY53203.1 - 6.9e-08 32.2 8.6 6.9e-08 32.2 8.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 ORY53203.1 - 1.1e-07 31.6 12.4 1.1e-07 31.6 12.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FHA PF00498.26 ORY53203.1 - 3.8e-07 30.4 0.0 8.5e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.6 ORY53203.1 - 4.8e-06 26.8 12.6 4.8e-06 26.8 12.6 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 ORY53203.1 - 5.4e-06 26.1 13.4 5.4e-06 26.1 13.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 ORY53203.1 - 2.9e-05 24.0 9.8 6.9e-05 22.8 9.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 ORY53203.1 - 4.4e-05 23.3 11.1 4.4e-05 23.3 11.1 1.8 2 0 0 2 2 2 1 zinc-RING finger domain U-box PF04564.15 ORY53203.1 - 0.00031 20.9 0.0 0.00081 19.5 0.0 1.7 1 0 0 1 1 1 1 U-box domain Prok-RING_4 PF14447.6 ORY53203.1 - 0.00067 19.5 9.7 0.00067 19.5 9.7 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 ORY53203.1 - 0.0093 16.1 13.3 0.0093 16.1 13.3 1.7 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 ORY53203.1 - 0.0094 16.2 9.0 0.028 14.7 9.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 ORY53203.1 - 0.0096 15.8 4.6 0.018 14.9 4.6 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 ORY53203.1 - 2 8.3 13.1 1 9.2 10.5 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF3090 PF11290.8 ORY53203.1 - 5.4 6.8 7.0 1.2 8.9 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3090) Sugar_tr PF00083.24 ORY53204.1 - 3.7e-23 82.1 5.7 1.5e-07 30.7 0.1 4.1 3 1 1 4 4 4 4 Sugar (and other) transporter Bunya_NS-S PF01104.17 ORY53204.1 - 0.022 14.6 0.2 0.051 13.4 0.2 1.5 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-s DUF4880 PF16220.5 ORY53204.1 - 0.053 13.4 0.6 0.31 11.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4880) Sugar_tr PF00083.24 ORY53205.1 - 2.8e-116 389.1 25.6 3.2e-116 388.9 25.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 ORY53205.1 - 6.3e-24 84.6 37.5 1.5e-14 53.7 15.2 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily DAO PF01266.24 ORY53206.1 - 7.1e-11 42.3 0.0 8.5e-09 35.5 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase HA2 PF04408.23 ORY53207.1 - 1.2e-17 64.2 1.0 9.1e-17 61.3 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 ORY53207.1 - 1.2e-06 28.8 0.1 2.9e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 ORY53207.1 - 1.7e-05 24.7 0.2 0.00028 20.7 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 ORY53207.1 - 0.05 13.9 4.3 0.42 10.9 3.1 2.9 3 1 0 3 3 3 0 AAA domain Rad17 PF03215.15 ORY53207.1 - 0.098 12.6 0.0 0.28 11.1 0.0 1.7 1 1 0 1 1 1 0 Rad17 P-loop domain Adeno_IVa2 PF02456.15 ORY53207.1 - 0.15 10.9 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein OB_NTP_bind PF07717.16 ORY53207.1 - 0.16 12.4 0.0 1.2 9.5 0.0 2.4 1 1 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold DALR_1 PF05746.15 ORY53208.1 - 0.0004 20.6 0.0 0.00062 19.9 0.0 1.2 1 0 0 1 1 1 1 DALR anticodon binding domain ArsR PF09824.9 ORY53209.1 - 0.04 13.5 0.2 0.052 13.1 0.2 1.2 1 0 0 1 1 1 0 ArsR transcriptional regulator RRM_1 PF00076.22 ORY53210.1 - 3e-13 49.4 0.6 2.5e-10 40.0 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DivIC PF04977.15 ORY53210.1 - 0.95 9.3 8.0 0.42 10.4 4.9 2.0 2 0 0 2 2 2 0 Septum formation initiator TH1 PF04858.13 ORY53211.1 - 1.4e-13 50.4 0.0 1.6e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 TH1 protein DUF1127 PF06568.11 ORY53211.1 - 0.54 10.0 4.8 1.1 9.1 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) Sugar_tr PF00083.24 ORY53213.1 - 1.4e-100 337.3 32.8 8.4e-79 265.5 13.6 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 ORY53213.1 - 7.2e-19 67.9 43.3 1.2e-11 44.2 13.0 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 ORY53214.1 - 8.8e-23 80.2 10.8 0.00085 20.1 0.0 10.1 10 1 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY53214.1 - 2.7e-11 43.6 0.2 0.082 13.2 0.0 6.1 3 2 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain SSXT PF05030.12 ORY53216.1 - 0.0039 16.8 0.1 0.0073 15.9 0.1 1.4 1 0 0 1 1 1 1 SSXT protein (N-terminal region) BBP2_2 PF10082.9 ORY53216.1 - 0.029 13.2 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative beta-barrel porin 2 UCH PF00443.29 ORY53217.1 - 4.7e-59 200.0 0.0 4.7e-59 200.0 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Asparaginase PF00710.20 ORY53217.1 - 3e-33 115.0 0.0 1.1e-19 70.7 0.0 2.8 1 1 1 2 2 2 2 Asparaginase, N-terminal Ank_2 PF12796.7 ORY53217.1 - 2.9e-22 79.0 0.4 6.2e-12 46.0 0.5 3.2 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 ORY53217.1 - 1.4e-17 63.8 1.9 3.7e-08 33.8 0.4 3.9 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY53217.1 - 3e-15 55.9 1.9 5.5e-07 29.8 0.1 5.0 4 0 0 4 4 4 3 Ankyrin repeat Asparaginase_C PF17763.1 ORY53217.1 - 6.5e-14 52.1 0.0 2.7e-11 43.7 0.0 2.7 1 1 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_3 PF13606.6 ORY53217.1 - 1.9e-11 43.1 2.5 0.0001 22.5 0.1 5.5 5 0 0 5 5 5 2 Ankyrin repeat USP8_dimer PF08969.11 ORY53217.1 - 8.6e-11 42.0 0.0 8.6e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 USP8 dimerisation domain Ank_5 PF13857.6 ORY53217.1 - 2.8e-09 37.0 0.2 1.3e-06 28.5 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Lipoprotein_6 PF01441.19 ORY53217.1 - 0.17 11.9 0.0 0.41 10.6 0.0 1.6 1 0 0 1 1 1 0 Lipoprotein Thioredoxin_6 PF13848.6 ORY53218.1 - 2.3e-12 47.2 8.3 2e-06 27.9 0.6 4.3 4 1 0 4 4 4 3 Thioredoxin-like domain Calsequestrin PF01216.17 ORY53218.1 - 3.2e-05 23.1 0.4 5.1e-05 22.5 0.4 1.4 1 0 0 1 1 1 1 Calsequestrin Thioredoxin PF00085.20 ORY53218.1 - 0.00015 21.7 0.1 0.00077 19.4 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin Bromo_TP_like PF17027.5 ORY53218.1 - 0.048 13.8 0.4 0.12 12.5 0.4 1.7 1 1 0 1 1 1 0 Histone-fold protein Glyco_hydro_47 PF01532.20 ORY53219.1 - 1.4e-89 301.1 0.5 4.3e-83 279.7 0.1 3.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 47 BTB PF00651.31 ORY53221.1 - 2.2e-16 60.0 0.1 3.2e-12 46.7 0.1 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.7 ORY53221.1 - 0.00012 22.6 0.0 0.00032 21.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY53221.1 - 0.024 15.0 0.0 0.15 12.4 0.0 2.4 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Arf PF00025.21 ORY53222.1 - 4.8e-77 257.3 0.2 5.9e-77 257.1 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 ORY53222.1 - 4.1e-15 56.0 0.1 5.6e-15 55.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 ORY53222.1 - 1.4e-14 54.0 0.0 1.7e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 ORY53222.1 - 2.7e-11 43.2 0.6 8.8e-07 28.4 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 ORY53222.1 - 6.6e-11 42.0 0.0 8.4e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 ORY53222.1 - 4e-10 39.4 0.0 5.3e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 ORY53222.1 - 2.5e-05 24.3 0.0 4.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 ORY53222.1 - 0.00023 20.8 0.1 0.055 13.1 0.0 2.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 ORY53222.1 - 0.00071 19.5 0.0 0.094 12.6 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase MeaB PF03308.16 ORY53222.1 - 0.0033 16.4 0.1 0.11 11.4 0.0 2.2 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 ORY53222.1 - 0.014 16.0 0.0 0.019 15.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.18 ORY53222.1 - 0.066 12.7 0.8 0.28 10.7 0.8 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 ORY53222.1 - 0.076 12.7 0.1 0.093 12.4 0.1 1.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 ORY53222.1 - 0.11 12.9 0.2 0.23 12.0 0.2 1.6 1 1 0 1 1 1 0 ABC transporter DUF2431 PF10354.9 ORY53223.1 - 7.2e-07 29.6 0.1 1e-06 29.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) GST_N PF02798.20 ORY53224.1 - 1.5e-10 41.2 0.0 2.8e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 ORY53224.1 - 1.8e-10 40.9 0.0 2.7e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY53224.1 - 1.1e-05 25.7 0.0 3e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY53224.1 - 3.9e-05 24.0 0.0 8.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 ORY53224.1 - 0.049 13.8 0.0 0.074 13.3 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY53224.1 - 0.072 13.1 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 ORY53224.1 - 0.075 13.8 0.0 0.14 13.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain UQ_con PF00179.26 ORY53225.1 - 1.8e-16 60.1 0.1 3e-16 59.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TPR_12 PF13424.6 ORY53226.1 - 1.4e-10 41.3 2.3 1.4e-06 28.5 0.6 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 ORY53226.1 - 1e-09 37.7 0.3 1.2e-07 31.0 0.1 2.9 3 0 0 3 3 3 1 SHNi-TPR TPR_2 PF07719.17 ORY53226.1 - 2.1e-07 30.5 6.9 0.073 13.2 0.0 4.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY53226.1 - 1.9e-05 24.3 0.4 0.41 10.8 0.1 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 ORY53226.1 - 4.9e-05 23.0 1.0 0.33 10.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY53226.1 - 8.5e-05 22.5 5.8 0.79 10.1 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat YebG PF07130.12 ORY53226.1 - 0.0037 17.1 1.4 0.0098 15.7 1.4 1.8 1 0 0 1 1 1 1 YebG protein TPR_11 PF13414.6 ORY53226.1 - 0.061 13.0 0.7 11 5.8 0.2 3.4 2 1 0 2 2 2 0 TPR repeat TPR_6 PF13174.6 ORY53226.1 - 0.19 12.4 2.6 24 5.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 ORY53226.1 - 1.5 9.9 6.4 65 4.7 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 ORY53226.1 - 6.5 7.5 16.8 12 6.7 0.1 4.9 3 2 1 4 4 4 0 Tetratricopeptide repeat ABC2_membrane PF01061.24 ORY53227.1 - 1.2 8.6 19.6 1.9 7.9 8.2 2.1 1 1 1 2 2 2 0 ABC-2 type transporter Baculo_IE-1 PF05290.11 ORY53228.1 - 0.00095 19.1 9.5 0.02 14.9 9.5 1.9 1 1 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_3 PF13920.6 ORY53228.1 - 0.0099 15.7 10.3 0.013 15.4 10.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zf_RING PF16744.5 ORY53228.1 - 0.18 11.9 6.1 0.09 12.9 2.0 2.0 1 1 2 3 3 3 0 KIAA1045 RING finger WAC_Acf1_DNA_bd PF10537.9 ORY53231.1 - 2.8e-28 98.4 0.5 2.8e-28 98.4 0.5 3.0 2 1 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.17 ORY53231.1 - 9.6e-08 32.2 0.0 2.1e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 DDT domain WSD PF15613.6 ORY53231.1 - 1.9e-06 28.3 6.1 1.9e-06 28.3 6.1 3.1 2 1 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DUF5097 PF17020.5 ORY53231.1 - 0.14 12.5 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5097) DUF3042 PF11240.8 ORY53231.1 - 1.6 8.8 10.9 1.7 8.7 1.9 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) Sporozoite_P67 PF05642.11 ORY53231.1 - 3.1 5.8 8.0 6.1 4.8 8.0 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF410 PF04190.13 ORY53232.1 - 4.1e-58 197.2 0.1 5.2e-58 196.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) CAP_N PF01213.19 ORY53233.1 - 0.027 14.0 0.5 0.2 11.1 0.1 2.4 3 1 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal DUF735 PF05246.11 ORY53233.1 - 0.053 13.5 0.2 0.095 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF735) RHH_8 PF17723.1 ORY53233.1 - 0.2 11.8 1.7 0.21 11.7 0.2 1.8 2 0 0 2 2 2 0 Ribbon-Helix-Helix transcriptional regulator family DUF3287 PF11690.8 ORY53233.1 - 0.28 10.9 3.0 0.2 11.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Prefoldin_2 PF01920.20 ORY53233.1 - 1.7 8.7 6.6 7.5 6.6 0.2 3.2 3 0 0 3 3 3 0 Prefoldin subunit FA_hydroxylase PF04116.13 ORY53234.1 - 7.2e-23 81.4 16.1 7.2e-23 81.4 16.1 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily NAD_binding_5 PF07994.12 ORY53235.1 - 1e-146 488.4 0.0 1.2e-146 488.2 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 ORY53235.1 - 1.8e-46 156.9 0.1 3.2e-46 156.1 0.1 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Npa1 PF11707.8 ORY53237.1 - 3.1e-82 276.6 0.0 1.5e-81 274.4 0.0 2.3 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 ORY53237.1 - 6.2e-52 176.1 0.2 3.3e-51 173.7 0.2 2.4 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 CDC45 PF02724.14 ORY53237.1 - 0.15 10.4 5.4 0.22 9.8 5.4 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.9 ORY53237.1 - 0.79 8.8 13.6 1.4 7.9 13.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.12 ORY53237.1 - 7.5 4.6 10.8 14 3.7 10.8 1.4 1 0 0 1 1 1 0 Nop14-like family Mito_carr PF00153.27 ORY53238.1 - 2.9e-51 171.4 3.8 5.6e-21 74.3 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Chromate_transp PF02417.15 ORY53238.1 - 0.71 10.0 5.2 22 5.1 5.3 2.9 1 1 0 1 1 1 0 Chromate transporter Glyco_transf_34 PF05637.12 ORY53240.1 - 1.9e-14 54.0 3.2 1.4e-11 44.6 3.2 2.3 1 1 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Histone_HNS PF00816.21 ORY53241.1 - 0.81 10.6 5.7 0.45 11.4 1.6 2.7 2 1 0 2 2 2 0 H-NS histone family Acetyltransf_10 PF13673.7 ORY53242.1 - 1.1e-13 51.3 0.0 1.5e-13 50.7 0.0 1.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY53242.1 - 1.6e-06 28.4 0.0 1.9e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY53242.1 - 0.00027 21.2 0.0 0.00032 20.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 ORY53242.1 - 0.00036 21.2 0.1 0.0021 18.7 0.1 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 ORY53243.1 - 8.7e-14 51.5 0.1 1e-13 51.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 ORY53243.1 - 5.8e-09 36.2 0.0 7.1e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 ORY53243.1 - 3.1e-08 33.9 0.1 4e-08 33.5 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 ORY53243.1 - 0.0021 18.7 0.0 0.012 16.3 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 ORY53243.1 - 0.023 14.8 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF4427 PF14468.6 ORY53243.1 - 0.025 14.7 0.1 0.039 14.0 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4427) FAM199X PF15814.5 ORY53244.1 - 1.6 7.7 9.0 2.5 7.1 9.0 1.2 1 0 0 1 1 1 0 Protein family FAM199X DUF2968 PF11180.8 ORY53245.1 - 0.015 14.9 5.2 0.025 14.2 5.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) CtIP_N PF10482.9 ORY53245.1 - 0.055 13.5 0.9 0.18 11.9 0.9 1.9 1 1 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain TSC22 PF01166.18 ORY53245.1 - 0.056 13.8 0.2 14 6.1 0.0 2.7 2 0 0 2 2 2 0 TSC-22/dip/bun family KASH_CCD PF14662.6 ORY53245.1 - 0.09 12.6 3.7 1.4 8.7 2.9 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH bZIP_1 PF00170.21 ORY53245.1 - 0.12 12.5 0.4 9.1 6.5 0.1 2.6 2 0 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.15 ORY53245.1 - 0.39 10.8 3.3 1.2 9.3 0.2 2.4 2 0 0 2 2 2 0 Basic region leucine zipper DivIC PF04977.15 ORY53245.1 - 4.5 7.1 9.6 6.6 6.6 0.1 2.5 1 1 1 2 2 2 0 Septum formation initiator TPR_MLP1_2 PF07926.12 ORY53245.1 - 8.4 6.5 19.7 0.024 14.7 6.7 2.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DcpS_C PF11969.8 ORY53246.1 - 2.4e-26 92.4 0.0 4.5e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 ORY53246.1 - 6.2e-07 30.2 0.2 1.2e-06 29.3 0.2 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal HIT PF01230.23 ORY53246.1 - 0.084 13.6 0.0 0.23 12.2 0.0 1.7 1 0 0 1 1 1 0 HIT domain MFS_1 PF07690.16 ORY53247.1 - 3.8e-46 157.6 59.4 3.8e-46 157.6 59.4 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY53247.1 - 4.6e-11 41.8 35.4 6.9e-11 41.3 35.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY53247.1 - 1.8e-06 27.1 10.9 1.8e-06 27.1 10.9 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter Pox_A14 PF05767.12 ORY53247.1 - 0.0061 16.7 1.9 0.0061 16.7 1.9 2.9 3 1 1 4 4 4 1 Poxvirus virion envelope protein A14 YecM PF06185.12 ORY53248.1 - 2.3e-20 73.0 0.0 3.2e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 YecM protein DUF2183 PF09949.9 ORY53249.1 - 1e-25 89.9 0.1 1.8e-25 89.2 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) WSC PF01822.19 ORY53250.1 - 9.9e-12 44.9 10.4 9.9e-12 44.9 10.4 2.5 2 0 0 2 2 2 1 WSC domain TPR_19 PF14559.6 ORY53252.1 - 7.1e-10 39.3 5.9 0.0007 20.1 0.0 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 ORY53252.1 - 0.0002 21.9 10.0 0.18 12.7 0.0 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY53252.1 - 0.00029 21.0 1.4 0.61 10.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY53252.1 - 0.00032 20.6 15.3 13 6.2 0.3 7.1 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY53252.1 - 0.0012 18.9 10.2 12 6.4 0.2 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY53252.1 - 0.0018 18.4 0.6 0.17 12.1 0.0 3.0 3 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 ORY53252.1 - 0.0044 16.7 4.0 0.29 10.8 0.0 3.8 4 1 0 4 4 4 1 TPR repeat BTAD PF03704.17 ORY53252.1 - 0.0045 17.4 1.5 5.5 7.4 0.0 3.8 4 0 0 4 4 4 1 Bacterial transcriptional activator domain TPR_7 PF13176.6 ORY53252.1 - 0.0046 16.9 3.6 9.2 6.6 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY53252.1 - 0.0071 17.0 0.4 0.21 12.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF883 PF05957.13 ORY53252.1 - 0.092 13.4 1.8 1.7 9.3 0.4 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) TPR_1 PF00515.28 ORY53252.1 - 0.13 12.1 7.3 41 4.2 0.0 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat MA3 PF02847.17 ORY53252.1 - 0.14 12.2 0.3 2 8.4 0.0 2.3 2 0 0 2 2 2 0 MA3 domain RRM_1 PF00076.22 ORY53253.1 - 4.1e-36 122.6 2.3 1.3e-17 63.3 0.0 3.8 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 ORY53253.1 - 1.5e-07 31.2 0.1 0.00061 19.6 0.0 2.6 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_8 PF11835.8 ORY53253.1 - 0.0037 17.4 0.0 0.21 11.8 0.0 3.2 3 0 0 3 3 3 1 RRM-like domain NRDE-2 PF08424.10 ORY53253.1 - 0.038 13.1 2.6 3.1 6.8 0.0 3.2 2 1 1 3 3 3 0 NRDE-2, necessary for RNA interference RRM_3 PF08777.11 ORY53253.1 - 0.078 13.0 1.3 7.3 6.7 0.0 3.6 4 0 0 4 4 4 0 RNA binding motif Lsm_interact PF05391.11 ORY53253.1 - 0.81 9.3 5.7 0.078 12.5 0.7 2.0 2 0 0 2 2 2 0 Lsm interaction motif Spt20 PF12090.8 ORY53253.1 - 1.5 8.3 9.6 3.6 7.1 9.6 1.5 1 0 0 1 1 1 0 Spt20 family U-box PF04564.15 ORY53256.1 - 7.2e-08 32.5 0.0 1.2e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 U-box domain DUF5102 PF17104.5 ORY53258.1 - 2.4e-11 44.2 4.7 6.4e-09 36.3 1.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF5102) FEZ PF07763.13 ORY53258.1 - 0.68 9.6 6.1 0.85 9.3 1.5 2.3 1 1 1 2 2 2 0 FEZ-like protein NolB PF17398.2 ORY53258.1 - 5.1 7.5 10.6 0.22 11.9 2.6 2.5 2 1 0 2 2 2 0 Nodulation protein NolB SOGA PF11365.8 ORY53259.1 - 0.13 13.4 1.1 0.18 12.9 0.1 1.7 2 0 0 2 2 2 0 Protein SOGA Sugar_tr PF00083.24 ORY53260.1 - 9.5e-75 252.2 21.2 2.8e-35 122.1 4.5 4.0 1 1 3 4 4 4 4 Sugar (and other) transporter MFS_1 PF07690.16 ORY53260.1 - 3.5e-13 49.2 37.0 4.8e-11 42.2 11.5 4.1 1 1 0 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 ORY53260.1 - 0.0003 19.5 1.0 0.0003 19.5 1.0 3.0 3 1 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.13 ORY53260.1 - 0.00097 17.7 1.2 0.0015 17.1 1.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.16 ORY53260.1 - 0.0075 14.6 0.7 0.012 13.9 0.7 1.4 1 0 0 1 1 1 1 BT1 family GST_N_3 PF13417.6 ORY53261.1 - 5.1e-06 26.8 0.0 9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 ORY53261.1 - 9.3e-05 22.4 1.0 0.00019 21.4 1.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 ORY53261.1 - 0.00035 20.7 0.1 0.00068 19.8 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY53261.1 - 0.0085 16.4 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tyr-DNA_phospho PF06087.12 ORY53262.1 - 4.9e-65 220.1 0.0 9.5e-54 182.9 0.0 2.1 1 1 1 2 2 2 2 Tyrosyl-DNA phosphodiesterase Pil1 PF13805.6 ORY53262.1 - 4e-19 69.2 0.8 5.7e-19 68.6 0.8 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 Lipase_GDSL_2 PF13472.6 ORY53264.1 - 0.0013 19.2 0.0 0.0021 18.5 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family hDGE_amylase PF14701.6 ORY53264.1 - 0.03 13.4 0.1 0.045 12.8 0.1 1.1 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Arrestin_C PF02752.22 ORY53266.1 - 8.8e-09 35.9 0.0 0.00072 20.0 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 ORY53266.1 - 0.00085 19.4 1.9 0.0011 19.0 0.0 2.2 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain DUF2299 PF10061.9 ORY53266.1 - 0.4 10.4 1.2 3 7.6 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2299) MFS_1 PF07690.16 ORY53267.1 - 1.9e-50 171.7 53.9 1.9e-50 171.7 53.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY53267.1 - 1.4e-11 43.6 28.7 1.9e-11 43.1 28.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY53267.1 - 2.1e-07 30.2 13.5 2.1e-07 30.2 13.5 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter DUF3015 PF11220.8 ORY53267.1 - 0.023 14.6 0.7 0.04 13.8 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) Pox_A14 PF05767.12 ORY53267.1 - 0.024 14.8 0.3 0.024 14.8 0.3 2.7 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 LRR_8 PF13855.6 ORY53268.1 - 4.6e-18 64.7 28.4 1.4e-06 27.9 0.6 6.2 3 2 3 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 ORY53268.1 - 8.1e-14 51.5 27.8 0.00044 20.6 2.2 6.3 6 1 0 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 ORY53268.1 - 0.0036 17.6 16.2 12 6.9 0.0 7.4 9 1 0 9 9 9 2 Leucine Rich Repeat LRR_9 PF14580.6 ORY53268.1 - 0.23 11.0 11.3 0.78 9.2 0.2 3.0 2 1 1 3 3 3 0 Leucine-rich repeat LRR_6 PF13516.6 ORY53268.1 - 2.5 8.4 15.1 12 6.3 0.5 6.0 6 0 0 6 6 6 0 Leucine Rich repeat PGP_phosphatase PF09419.10 ORY53269.1 - 2.4e-40 137.9 0.0 3.1e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 ORY53269.1 - 1.9e-06 27.9 0.0 3.1e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 ORY53269.1 - 0.0004 20.7 0.0 0.34 11.2 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Ribosomal_L19 PF01245.20 ORY53270.1 - 5.2e-12 45.7 0.0 8.5e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 ADH_zinc_N_2 PF13602.6 ORY53274.1 - 2.4e-12 48.1 0.0 4.2e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 ORY53274.1 - 7.9e-10 38.8 0.3 1.7e-09 37.7 0.3 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 ORY53274.1 - 0.015 15.2 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Ribonuclease_3 PF00636.26 ORY53275.1 - 1.3e-43 147.9 0.0 1.3e-20 74.0 0.0 3.2 2 1 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 ORY53275.1 - 6.2e-36 123.4 0.0 1.9e-19 70.1 0.0 2.2 2 0 0 2 2 2 2 Ribonuclease-III-like DUF4351 PF14261.6 ORY53275.1 - 0.025 14.6 0.8 1.6 8.8 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4351) ResIII PF04851.15 ORY53278.1 - 2.3e-06 27.7 0.0 1.2e-05 25.4 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 ORY53278.1 - 3.7e-06 26.8 0.0 5.8e-06 26.2 0.0 1.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF3638 PF12340.8 ORY53278.1 - 0.022 14.1 0.1 0.031 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) AAA_26 PF13500.6 ORY53278.1 - 0.034 14.0 0.2 0.04 13.8 0.2 1.3 1 1 0 1 1 1 0 AAA domain DUF1223 PF06764.11 ORY53278.1 - 0.13 12.3 1.0 1.5 8.9 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1223) Nic96 PF04097.14 ORY53279.1 - 2.2e-90 303.9 0.0 1.8e-89 300.9 0.0 2.0 1 1 0 1 1 1 1 Nup93/Nic96 SPX PF03105.19 ORY53279.1 - 9.5 6.0 9.7 15 5.3 9.7 1.2 1 0 0 1 1 1 0 SPX domain NIF PF03031.18 ORY53280.1 - 1.3e-38 132.2 0.0 1.5e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ZZ PF00569.17 ORY53282.1 - 5.8e-07 29.2 6.4 9.5e-07 28.5 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type CENP-F_leu_zip PF10473.9 ORY53282.1 - 0.039 14.0 1.4 0.074 13.1 0.6 1.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4881 PF16222.5 ORY53282.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4881) Prefoldin_2 PF01920.20 ORY53282.1 - 0.26 11.3 3.9 0.63 10.0 3.9 1.6 1 0 0 1 1 1 0 Prefoldin subunit zf-B_box PF00643.24 ORY53282.1 - 0.28 11.3 4.7 0.94 9.7 4.7 1.9 1 1 0 1 1 1 0 B-box zinc finger DUF3713 PF12506.8 ORY53282.1 - 0.4 11.0 2.4 0.29 11.5 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) ABC_tran_CTD PF16326.5 ORY53282.1 - 0.74 10.1 5.7 0.41 10.9 1.8 2.5 2 1 0 2 2 2 0 ABC transporter C-terminal domain zf-UBR PF02207.20 ORY53282.1 - 2.4 8.4 7.3 48 4.2 7.3 2.2 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Rhodanese PF00581.20 ORY53283.1 - 0.0013 19.2 0.0 0.002 18.6 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain WD40 PF00400.32 ORY53284.1 - 8.5e-23 80.2 10.2 3.1e-09 37.3 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat WD40_like PF17005.5 ORY53284.1 - 1.2e-05 24.8 0.0 3.6e-05 23.2 0.0 1.7 2 0 0 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 ORY53284.1 - 0.00037 19.6 0.0 0.0012 17.9 0.0 1.8 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 ORY53284.1 - 0.0038 17.5 0.0 0.33 11.3 0.0 3.2 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3913 PF13052.6 ORY53284.1 - 0.047 13.9 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3913) Proteasome_A_N PF10584.9 ORY53284.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Chitin_synth_2 PF03142.15 ORY53285.1 - 4.2e-226 751.6 0.0 7.7e-226 750.8 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 ORY53285.1 - 3.6e-84 283.3 0.0 4.8e-84 282.9 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 ORY53285.1 - 7.2e-20 70.7 0.1 1.2e-18 66.8 0.1 2.6 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.6 ORY53285.1 - 7.9e-10 39.0 0.9 1.8e-09 37.8 0.9 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 ORY53285.1 - 2.1e-09 37.6 0.0 9.8e-08 32.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 ORY53285.1 - 2.7e-05 24.1 0.0 0.06 13.1 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferase family 2 CDKN3 PF05706.12 ORY53287.1 - 2.4e-10 40.3 0.1 3e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) DSPc PF00782.20 ORY53287.1 - 1.4e-08 34.7 0.0 1.8e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 ORY53287.1 - 0.0032 17.1 0.1 0.0036 16.9 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 ORY53287.1 - 0.0061 16.7 0.0 0.0078 16.3 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF442 PF04273.13 ORY53287.1 - 0.0076 16.3 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Putative phosphatase (DUF442) Y_phosphatase3 PF13350.6 ORY53287.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.5 1 1 0 1 1 1 0 Tyrosine phosphatase family Sds3 PF08598.11 ORY53289.1 - 0.05 13.6 0.0 0.058 13.4 0.0 1.1 1 0 0 1 1 1 0 Sds3-like TIR_2 PF13676.6 ORY53290.1 - 6.1e-23 81.7 0.0 3.1e-11 43.9 0.0 2.8 2 0 0 2 2 2 2 TIR domain TIR PF01582.20 ORY53290.1 - 7.2e-05 22.7 0.0 0.11 12.2 0.0 2.6 3 0 0 3 3 3 2 TIR domain TIR_2 PF13676.6 ORY53291.1 - 2.1e-11 44.5 0.0 5.6e-11 43.1 0.0 1.8 2 0 0 2 2 2 1 TIR domain TIR PF01582.20 ORY53291.1 - 0.028 14.2 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 TIR domain Anoctamin PF04547.12 ORY53292.1 - 1.4e-101 340.6 10.1 1.8e-101 340.3 10.1 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Anoct_dimer PF16178.5 ORY53292.1 - 1e-19 71.2 0.3 2.1e-19 70.1 0.3 1.5 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin EPSP_synthase PF00275.20 ORY53293.1 - 2.5e-121 405.3 0.0 3.8e-121 404.7 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 ORY53293.1 - 5.4e-101 337.2 0.2 7.7e-101 336.7 0.2 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 ORY53293.1 - 9.5e-06 25.5 0.1 5.4e-05 23.0 0.1 2.0 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase CDC45 PF02724.14 ORY53294.1 - 0.00062 18.2 11.2 0.00075 17.9 11.2 1.1 1 0 0 1 1 1 1 CDC45-like protein CDC27 PF09507.10 ORY53294.1 - 0.0015 18.0 17.5 0.002 17.6 17.5 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Asp-B-Hydro_N PF05279.11 ORY53294.1 - 3 7.8 22.6 4.6 7.2 22.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RR_TM4-6 PF06459.12 ORY53294.1 - 5.8 6.7 16.6 11 5.7 16.6 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Nop53 PF07767.11 ORY53294.1 - 7 5.9 34.9 11 5.3 34.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Spore_coat_CotO PF14153.6 ORY53294.1 - 8.1 6.3 24.2 13 5.6 24.2 1.3 1 0 0 1 1 1 0 Spore coat protein CotO WD40 PF00400.32 ORY53296.1 - 3.3e-41 138.5 26.3 1.2e-07 32.2 1.8 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY53296.1 - 1e-10 41.8 1.1 0.36 11.2 0.0 6.0 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY53296.1 - 2.7e-06 27.4 0.0 0.24 11.3 0.0 3.6 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 ORY53296.1 - 0.00025 20.5 2.6 0.23 10.8 0.1 4.0 4 1 1 5 5 5 2 WD40-like domain LisH_TPL PF17814.1 ORY53296.1 - 0.00038 20.1 0.0 0.00086 18.9 0.0 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain Nup160 PF11715.8 ORY53296.1 - 0.01 14.6 6.9 1.3 7.6 0.1 4.1 3 2 2 5 5 5 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 ORY53296.1 - 0.01 14.8 0.3 1.7 7.5 0.0 3.0 1 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein LysM PF01476.20 ORY53300.1 - 4.7e-07 29.8 0.0 0.0061 16.6 0.0 3.6 3 0 0 3 3 3 2 LysM domain Dicty_REP PF05086.12 ORY53300.1 - 0.42 8.5 8.6 0.58 8.1 8.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TIR_2 PF13676.6 ORY53301.1 - 1.9e-13 51.0 0.0 5e-12 46.5 0.0 2.1 2 0 0 2 2 2 1 TIR domain TIR PF01582.20 ORY53301.1 - 7.5e-08 32.4 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 TIR domain B12-binding PF02310.19 ORY53301.1 - 0.021 14.9 0.0 0.032 14.3 0.0 1.2 1 0 0 1 1 1 0 B12 binding domain PC-Esterase PF13839.6 ORY53302.1 - 0.046 13.5 0.2 0.1 12.4 0.0 1.6 2 0 0 2 2 2 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Metallophos PF00149.28 ORY53406.1 - 1.2e-23 84.7 0.0 1.9e-23 84.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FAD_binding_6 PF00970.24 ORY53407.1 - 7.1e-34 116.1 0.0 1.1e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 ORY53407.1 - 1.8e-31 109.0 0.0 2.6e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 ORY53407.1 - 2.1e-06 27.9 0.0 0.00015 21.9 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain RIX1 PF08167.12 ORY53408.1 - 3.2e-15 56.4 2.6 3.2e-15 56.4 2.6 1.9 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Asn_synthase PF00733.21 ORY53409.1 - 4.6e-51 174.5 0.0 7.4e-30 104.8 0.0 2.2 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 ORY53409.1 - 4.1e-38 130.1 0.0 6.9e-38 129.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 ORY53409.1 - 6e-33 113.9 0.0 1.5e-32 112.6 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 ORY53409.1 - 0.0033 16.9 0.1 0.0076 15.7 0.1 1.5 1 0 0 1 1 1 1 Aluminium induced protein AA_permease PF00324.21 ORY53412.1 - 5.5e-104 348.4 39.0 6.9e-104 348.1 39.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 ORY53412.1 - 1.7e-40 139.2 46.4 2.2e-40 138.8 46.4 1.1 1 0 0 1 1 1 1 Amino acid permease F-box-like PF12937.7 ORY53413.1 - 0.0027 17.6 5.7 0.17 11.8 0.6 3.1 3 0 0 3 3 3 2 F-box-like F-box_4 PF15966.5 ORY53413.1 - 0.0073 16.2 1.4 4.3 7.3 0.1 3.5 3 0 0 3 3 3 1 F-box F-box PF00646.33 ORY53413.1 - 0.046 13.6 2.1 3.3 7.7 0.4 3.2 2 0 0 2 2 2 0 F-box domain TPR_12 PF13424.6 ORY53414.1 - 1.8e-09 37.8 6.5 0.002 18.3 0.0 4.9 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 ORY53414.1 - 2.2e-08 33.5 1.8 2.2 8.5 0.0 6.4 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 ORY53414.1 - 2.5e-06 27.1 0.4 0.14 12.3 0.0 5.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY53414.1 - 6.5e-06 25.7 0.1 0.06 13.2 0.0 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY53414.1 - 1.9e-05 24.5 0.3 2.2 8.7 0.0 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 ORY53414.1 - 3.4e-05 24.4 3.1 4.8 7.9 0.0 5.0 4 1 0 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.9 ORY53414.1 - 0.00035 20.3 2.6 1.9 8.2 0.0 4.3 3 1 1 4 4 4 2 26S proteasome subunit RPN7 TPR_14 PF13428.6 ORY53414.1 - 0.025 15.4 2.3 22 6.2 0.0 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 ORY53414.1 - 0.052 13.4 0.0 89 3.2 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Zn_clus PF00172.18 ORY53415.1 - 1.6e-07 31.4 23.7 0.00014 21.9 6.6 2.4 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY53415.1 - 1.8e-05 23.9 0.3 3.7e-05 22.9 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain bZIP_1 PF00170.21 ORY53416.1 - 9.1e-07 28.9 38.7 0.0015 18.6 6.8 4.9 3 2 2 5 5 5 3 bZIP transcription factor Myb_CC_LHEQLE PF14379.6 ORY53416.1 - 0.031 14.0 3.9 1.4 8.7 0.7 2.8 2 0 0 2 2 2 0 MYB-CC type transfactor, LHEQLE motif DUF5321 PF17254.2 ORY53416.1 - 0.086 12.3 9.6 0.48 9.8 2.4 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5321) NAS PF03059.16 ORY53416.1 - 0.13 11.6 0.2 5.8 6.2 0.0 2.3 2 0 0 2 2 2 0 Nicotianamine synthase protein TSC22 PF01166.18 ORY53416.1 - 0.16 12.3 7.2 4.9 7.6 0.2 3.5 4 0 0 4 4 3 0 TSC-22/dip/bun family Cep57_MT_bd PF06657.13 ORY53416.1 - 0.24 11.9 7.5 6.4 7.3 0.2 3.8 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF3045 PF11243.8 ORY53416.1 - 0.41 10.8 2.1 19 5.5 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3045) Glutaredoxin2_C PF04399.13 ORY53416.1 - 0.71 9.7 4.5 2.4 8.0 0.6 2.8 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain SMN PF06003.12 ORY53416.1 - 0.75 9.0 10.0 0.84 8.8 3.2 2.7 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) NAPRTase_N PF17767.1 ORY53416.1 - 0.92 9.9 3.7 5.4 7.4 0.3 2.6 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF2937 PF11157.8 ORY53416.1 - 2.8 7.6 6.9 2 8.1 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) SpecificRecomb PF10136.9 ORY53416.1 - 4.6 5.4 8.1 3 6.1 1.4 2.2 2 0 0 2 2 2 0 Site-specific recombinase FapA PF03961.13 ORY53416.1 - 8.3 4.9 10.2 2.2 6.8 3.4 2.7 3 1 0 3 3 3 0 Flagellar Assembly Protein A Exonuc_VII_S PF02609.16 ORY53416.1 - 8.6 6.5 11.6 16 5.6 2.2 3.5 3 1 1 4 4 4 0 Exonuclease VII small subunit zf-HC5HC2H_2 PF13832.6 ORY53418.1 - 0.024 14.8 11.2 0.47 10.6 1.2 2.7 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 ORY53418.1 - 0.13 12.5 14.2 0.53 10.6 1.9 2.9 2 0 0 2 2 2 0 PHD-like zinc-binding domain PIF1 PF05970.14 ORY53421.1 - 1.1e-14 54.4 0.0 1.2e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 ORY53421.1 - 6.6e-07 29.2 0.0 7.7e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain Apolipoprotein PF01442.18 ORY53423.1 - 0.0015 18.5 0.0 0.14 12.0 0.0 2.6 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain PIN_8 PF18476.1 ORY53423.1 - 0.012 15.4 4.8 0.36 10.6 0.5 2.4 2 1 0 2 2 2 0 PIN like domain dCache_2 PF08269.11 ORY53423.1 - 0.037 13.2 1.2 0.076 12.2 1.2 1.5 1 0 0 1 1 1 0 Cache domain DUF2313 PF10076.9 ORY53423.1 - 0.051 13.4 0.3 2.2 8.1 0.0 2.8 2 1 1 3 3 3 0 Uncharacterised protein conserved in bacteria (DUF2313) Prominin PF05478.11 ORY53423.1 - 0.075 11.0 4.0 0.21 9.5 0.3 2.1 1 1 1 2 2 2 0 Prominin Tweety PF04906.13 ORY53423.1 - 0.084 11.5 0.0 0.084 11.5 0.0 2.4 2 1 1 3 3 3 0 Tweety Nbl1_Borealin_N PF10444.9 ORY53423.1 - 0.15 11.7 0.0 1.3 8.7 0.0 2.6 2 1 0 2 2 2 0 Nbl1 / Borealin N terminal ApoLp-III PF07464.11 ORY53423.1 - 5.3 7.1 13.0 0.36 10.9 4.7 2.7 2 2 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) ATP_synt_H PF05493.13 ORY53424.1 - 6.6e-20 71.3 1.3 8.4e-20 71.0 1.3 1.1 1 0 0 1 1 1 1 ATP synthase subunit H Ribosomal_L11_N PF03946.14 ORY53425.1 - 7.2e-27 93.0 0.3 1.2e-26 92.3 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 ORY53425.1 - 6e-24 84.3 0.0 9e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain SNF2_N PF00176.23 ORY53426.1 - 1.2e-40 139.4 0.3 2.2e-40 138.5 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.25 ORY53426.1 - 3.9e-15 55.7 0.0 1.3e-14 54.0 0.0 1.9 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 ORY53426.1 - 1.3e-05 25.5 0.1 4.4e-05 23.8 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2452 PF10504.9 ORY53426.1 - 0.11 11.9 0.1 0.27 10.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) PLAC8 PF04749.17 ORY53427.1 - 1.2e-23 84.0 19.2 1.8e-23 83.4 19.2 1.4 1 0 0 1 1 1 1 PLAC8 family Zn_clus PF00172.18 ORY53428.1 - 5.1e-10 39.3 58.1 0.0014 18.7 10.0 4.6 4 0 0 4 4 4 4 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY53428.1 - 7.2e-05 21.9 5.4 0.063 12.3 0.8 2.7 2 0 0 2 2 2 2 Fungal specific transcription factor domain Peptidase_C54 PF03416.19 ORY53428.1 - 0.018 14.5 0.1 4.4 6.6 0.0 2.3 2 0 0 2 2 2 0 Peptidase family C54 DUF4007 PF13182.6 ORY53428.1 - 0.019 14.1 0.6 3.9 6.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4007) HEPN_SAV2148 PF18725.1 ORY53428.1 - 0.054 12.9 0.3 7.2 6.0 0.0 2.5 2 0 0 2 2 2 0 SAV2148-like HEPN CLAMP PF14769.6 ORY53428.1 - 0.093 13.2 0.4 18 5.9 0.1 3.0 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 PMT PF02366.18 ORY53429.1 - 1.9e-81 273.3 15.0 1.9e-81 273.3 15.0 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 ORY53429.1 - 4.8e-59 199.3 14.1 4.8e-59 199.3 14.1 2.1 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 ORY53429.1 - 3.5e-28 98.7 0.0 5.9e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 MIR domain Putative_PNPOx PF01243.20 ORY53430.1 - 2.9e-07 30.6 0.1 0.0013 18.9 0.0 3.4 3 1 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_1 PF00175.21 ORY53430.1 - 5.1e-06 27.1 0.0 1e-05 26.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 ORY53430.1 - 0.0042 17.2 0.0 0.19 11.9 0.0 2.4 2 0 0 2 2 2 1 Ferric reductase NAD binding domain RNA_ligase PF09414.10 ORY53431.1 - 0.14 12.5 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 RNA ligase PEPCK_ATP PF01293.20 ORY53432.1 - 4.1e-225 747.8 0.0 4.8e-225 747.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase CDC37_N PF03234.14 ORY53433.1 - 2.4e-28 99.6 5.1 2.4e-28 99.6 5.1 3.2 2 1 1 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 ORY53433.1 - 5e-26 91.0 0.0 1.3e-25 89.6 0.0 1.7 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 ORY53433.1 - 5.3e-09 36.1 0.1 5.3e-09 36.1 0.1 2.7 3 0 0 3 3 3 1 Cdc37 C terminal domain TetR_C_4 PF08359.11 ORY53433.1 - 0.00014 22.0 2.2 0.0011 19.1 0.2 2.3 2 0 0 2 2 2 1 YsiA-like protein, C-terminal region POTRA_TamA_1 PF17243.2 ORY53433.1 - 0.12 12.5 1.0 0.41 10.8 0.4 2.1 2 0 0 2 2 2 0 POTRA domain TamA domain 1 BSD PF03909.17 ORY53434.1 - 7.8e-15 54.6 0.9 4.9e-11 42.5 0.2 3.2 3 0 0 3 3 3 2 BSD domain F-box_4 PF15966.5 ORY53435.1 - 0.0012 18.7 0.0 0.0029 17.5 0.0 1.6 1 0 0 1 1 1 1 F-box NYD-SP28_assoc PF14775.6 ORY53435.1 - 0.031 14.4 1.9 0.061 13.4 1.9 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain Tup_N PF08581.10 ORY53435.1 - 0.066 13.5 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Tup N-terminal DJ-1_PfpI PF01965.24 ORY53436.1 - 3.1e-20 72.6 0.5 1.4e-19 70.5 0.2 1.9 2 0 0 2 2 2 1 DJ-1/PfpI family F-box_4 PF15966.5 ORY53438.1 - 0.0059 16.5 0.0 0.092 12.6 0.0 2.6 2 0 0 2 2 2 1 F-box F-box_4 PF15966.5 ORY53441.1 - 0.0039 17.1 0.1 0.0089 15.9 0.1 1.6 1 0 0 1 1 1 1 F-box F-box PF00646.33 ORY53441.1 - 0.083 12.8 0.1 0.24 11.3 0.1 1.8 1 0 0 1 1 1 0 F-box domain Abhydrolase_1 PF00561.20 ORY53442.1 - 1e-18 67.9 0.1 2.2e-17 63.5 0.1 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 ORY53442.1 - 2.9e-18 65.9 0.0 8.3e-18 64.4 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein KDZ PF18758.1 ORY53443.1 - 1.7e-20 73.6 0.0 2.7e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase TFIIA PF03153.13 ORY53445.1 - 0.0029 17.7 9.9 0.0064 16.5 9.9 1.5 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit F-box_4 PF15966.5 ORY53446.1 - 0.16 11.8 0.2 1.2 9.0 0.1 2.1 2 0 0 2 2 2 0 F-box MIF4G_like_2 PF09090.11 ORY53447.1 - 4.3e-42 144.4 3.2 6.3e-42 143.9 3.2 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.11 ORY53447.1 - 3.7e-39 134.5 0.0 2.5e-34 118.7 0.0 3.2 2 1 1 3 3 3 2 MIF4G like MIF4G PF02854.19 ORY53447.1 - 0.00034 20.3 0.0 0.0041 16.8 0.0 2.5 3 0 0 3 3 3 1 MIF4G domain TAF6_C PF07571.13 ORY53447.1 - 0.013 15.8 0.2 0.25 11.7 0.1 2.7 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain PEX11 PF05648.14 ORY53448.1 - 3.4e-49 167.3 0.6 4.2e-49 167.0 0.6 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF2917 PF11142.8 ORY53448.1 - 0.011 15.1 0.0 0.03 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) DUF3087 PF11286.8 ORY53448.1 - 0.03 13.8 0.7 0.083 12.4 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) Aegerolysin PF06355.13 ORY53448.1 - 0.15 12.1 0.0 1.9 8.6 0.0 2.0 2 0 0 2 2 2 0 Aegerolysin Fungal_trans PF04082.18 ORY53449.1 - 0.013 14.6 0.5 0.026 13.6 0.1 1.8 2 0 0 2 2 2 0 Fungal specific transcription factor domain Zn_clus PF00172.18 ORY53450.1 - 0.00014 21.9 16.7 0.0038 17.3 7.3 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY53450.1 - 0.0012 18.0 0.1 0.0026 16.8 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain PSI_integrin PF17205.3 ORY53450.1 - 5.1 6.9 14.6 0.48 10.2 0.7 3.4 1 1 1 3 3 3 0 Integrin plexin domain UPRTase PF14681.6 ORY53451.1 - 2.6e-62 210.0 0.0 3.1e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 ORY53451.1 - 6.6e-05 22.5 0.1 0.00011 21.7 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain TRAM_LAG1_CLN8 PF03798.16 ORY53452.1 - 1.7e-13 50.8 4.9 2.4e-13 50.3 4.9 1.2 1 0 0 1 1 1 1 TLC domain Urate_ox_N PF06181.11 ORY53452.1 - 0.033 13.5 3.7 0.029 13.7 2.3 1.5 2 0 0 2 2 2 0 Urate oxidase N-terminal DUF3593 PF12159.8 ORY53452.1 - 0.79 9.8 5.4 0.6 10.2 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3593) TRAM_LAG1_CLN8 PF03798.16 ORY53454.1 - 1.4e-35 122.8 21.9 1.6e-35 122.6 21.9 1.0 1 0 0 1 1 1 1 TLC domain CBP_BcsF PF11120.8 ORY53454.1 - 0.2 11.8 1.3 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsF Pyr_redox_2 PF07992.14 ORY53455.1 - 1.4e-12 47.4 0.1 2.4e-06 27.0 0.0 3.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 ORY53455.1 - 0.0057 15.6 0.1 0.01 14.7 0.1 1.4 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 ORY53456.1 - 2.6e-27 95.8 0.0 6.2e-27 94.6 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 ORY53456.1 - 2.3e-10 40.9 0.0 2.3e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 ORY53456.1 - 1.6e-05 24.2 0.3 7.5e-05 22.0 0.2 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 ORY53456.1 - 9.7e-05 21.8 1.3 0.00024 20.5 1.3 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 ORY53456.1 - 0.00062 19.5 0.5 0.56 9.7 1.0 3.4 4 0 0 4 4 4 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 ORY53456.1 - 0.00075 18.6 0.2 0.43 9.6 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_9 PF13454.6 ORY53456.1 - 0.0027 17.7 0.3 0.26 11.3 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.22 ORY53456.1 - 0.027 13.6 0.2 0.85 8.6 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 ORY53456.1 - 0.087 11.5 0.6 3.9 6.1 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein ESSS PF10183.9 ORY53457.1 - 0.0077 16.4 0.0 0.0084 16.3 0.0 1.2 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MFS_1 PF07690.16 ORY53458.1 - 1.9e-47 161.9 53.8 1.9e-47 161.9 53.8 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 ORY53458.1 - 8e-12 44.4 33.1 1.2e-11 43.8 33.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 ORY53458.1 - 7.1e-06 25.1 13.1 7.1e-06 25.1 13.1 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter Pox_A14 PF05767.12 ORY53458.1 - 0.012 15.8 1.4 0.012 15.8 1.4 2.9 3 1 1 4 4 4 0 Poxvirus virion envelope protein A14 DUF2367 PF10164.9 ORY53458.1 - 2.7 8.6 0.0 2.7 8.6 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2367) F-box_4 PF15966.5 ORY53459.1 - 0.0024 17.7 0.1 0.0071 16.2 0.0 1.9 2 1 0 2 2 2 1 F-box Kinesin PF00225.23 ORY53460.1 - 8e-119 396.5 0.1 9.3e-119 396.2 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 ORY53460.1 - 1.7e-30 105.9 0.3 1.1e-29 103.3 0.0 2.2 2 0 0 2 2 2 1 Microtubule binding AAA_7 PF12775.7 ORY53460.1 - 0.22 11.0 2.5 0.36 10.3 0.1 2.3 2 1 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 ORY53460.1 - 8.1 6.5 7.8 91 3.0 4.2 2.7 2 1 0 2 2 2 0 Helicase HerA, central domain WW PF00397.26 ORY53461.1 - 3.9e-14 52.4 12.8 3.4e-10 39.8 1.5 2.1 2 0 0 2 2 2 2 WW domain CT_C_D PF02682.16 ORY53463.1 - 0.046 13.5 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D ORC5_C PF14630.6 ORY53464.1 - 1.2e-23 84.0 2.4 2.1e-12 47.2 0.1 2.2 1 1 1 2 2 2 2 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 ORY53464.1 - 9.8e-05 22.8 0.3 0.00076 19.9 0.3 2.6 1 1 1 2 2 2 1 AAA ATPase domain BCL9 PF11502.8 ORY53464.1 - 0.092 12.6 0.8 2.1 8.2 0.8 2.4 2 0 0 2 2 2 0 B-cell lymphoma 9 protein Amidase PF01425.21 ORY53466.1 - 6.6e-70 236.3 0.2 6.2e-69 233.1 0.2 1.9 1 1 0 1 1 1 1 Amidase Spherulin4 PF12138.8 ORY53467.1 - 4.4e-89 298.2 32.2 1.2e-37 129.8 9.0 3.0 3 0 0 3 3 3 3 Spherulation-specific family 4 Arr-ms PF12120.8 ORY53467.1 - 0.0035 17.5 1.2 0.43 10.8 0.1 3.1 3 0 0 3 3 3 1 Rifampin ADP-ribosyl transferase DUF1256 PF06866.11 ORY53467.1 - 0.15 11.5 0.0 0.29 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) SMC_Nse1 PF07574.13 ORY53467.1 - 0.18 11.7 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex NHL PF01436.21 ORY53467.1 - 0.3 11.2 1.7 27 5.0 0.1 2.8 2 0 0 2 2 2 0 NHL repeat F-box_4 PF15966.5 ORY53468.1 - 0.0062 16.4 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 ORY53468.1 - 0.019 14.8 0.1 0.043 13.7 0.1 1.6 1 0 0 1 1 1 0 F-box-like Rogdi_lz PF10259.9 ORY53468.1 - 0.089 12.2 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein Cyclin_N PF00134.23 ORY53469.1 - 3.4e-26 91.5 3.2 5.1e-26 90.9 3.2 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain WW PF00397.26 ORY53470.1 - 7.6e-12 45.1 0.4 1.3e-11 44.4 0.4 1.4 1 0 0 1 1 1 1 WW domain DrsE PF02635.15 ORY53470.1 - 0.091 13.1 0.0 0.58 10.5 0.0 2.1 2 1 0 2 2 2 0 DsrE/DsrF-like family DUF2076 PF09849.9 ORY53470.1 - 0.68 9.9 14.9 7.6 6.5 14.9 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Cas9_Topo PF17894.1 ORY53471.1 - 0.041 13.9 0.0 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 EVE PF01878.18 ORY53472.1 - 1.3e-50 171.1 0.0 1.5e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 EVE domain CTD_bind PF04818.13 ORY53473.1 - 0.00048 20.9 0.0 0.0013 19.6 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf_UBZ PF18439.1 ORY53473.1 - 0.14 11.7 4.9 1.9 8.1 4.9 2.3 1 1 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Med18 PF09637.10 ORY53475.1 - 5.3e-23 82.1 0.0 1.9e-20 73.8 0.0 2.0 1 1 1 2 2 2 2 Med18 protein DUF1674 PF07896.12 ORY53475.1 - 0.031 14.8 0.0 0.055 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1674) Glycos_transf_2 PF00535.26 ORY53476.1 - 3.6e-27 95.2 0.0 4.8e-27 94.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 ORY53476.1 - 1.1e-11 45.1 0.2 1.7e-11 44.5 0.2 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 ORY53476.1 - 0.00042 19.9 0.0 0.00062 19.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 ORY53476.1 - 0.016 15.8 0.0 0.031 14.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 YAcAr PF10686.9 ORY53476.1 - 0.046 13.7 0.1 6.1 6.9 0.0 2.7 3 0 0 3 3 3 0 YspA, cpYpsA-related SLOG family FH2 PF02181.23 ORY53477.1 - 2.3e-94 316.6 6.8 2.3e-94 316.6 6.8 2.3 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 ORY53477.1 - 1.6e-37 129.1 0.0 7.5e-37 126.8 0.0 2.2 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 ORY53477.1 - 2.3e-31 108.8 0.1 6.3e-31 107.4 0.1 1.8 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Bud13 PF09736.9 ORY53477.1 - 0.29 11.5 3.5 0.91 9.9 0.0 2.6 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Syntaxin_2 PF14523.6 ORY53477.1 - 0.88 10.0 7.1 5.5 7.4 0.2 3.4 3 0 0 3 3 3 0 Syntaxin-like protein YlqD PF11068.8 ORY53478.1 - 0.08 13.3 0.1 0.13 12.7 0.1 1.2 1 0 0 1 1 1 0 YlqD protein MFS_4 PF06779.14 ORY53478.1 - 0.09 12.1 5.2 0.024 13.9 2.2 1.5 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB SPC25 PF06703.11 ORY53478.1 - 0.092 12.5 1.6 0.16 11.8 1.6 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF2694 PF10904.8 ORY53479.1 - 0.014 15.4 0.0 0.037 14.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2694) Spt5-NGN PF03439.13 ORY53480.1 - 3.7e-19 68.4 0.0 6.4e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 ORY53480.1 - 7.8e-19 66.9 26.9 4.3e-07 29.7 0.6 7.2 7 0 0 7 7 7 5 KOW motif Spt5_N PF11942.8 ORY53480.1 - 2.7e-14 54.0 12.9 2.7e-14 54.0 12.9 3.0 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 ORY53480.1 - 5.1e-11 43.0 11.2 5.1e-11 43.0 11.2 2.7 2 1 0 2 2 2 1 Spt5 C-terminal nonapeptide repeat binding Spt4 Aminotran_5 PF00266.19 ORY53481.1 - 1.5e-11 43.9 0.0 2.1e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 ORY53481.1 - 0.07 11.6 0.0 0.099 11.2 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme 2-oxoacid_dh PF00198.23 ORY53482.1 - 1.5e-67 227.5 0.0 4e-67 226.1 0.0 1.7 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 ORY53482.1 - 2.6e-15 56.5 0.1 7.5e-15 55.0 0.1 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl PF00364.22 ORY53482.1 - 1.8e-14 53.3 0.5 3.3e-14 52.5 0.5 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Hydrolase_3 PF08282.12 ORY53483.1 - 1.5e-10 41.3 0.0 2.3e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 ORY53483.1 - 2.3e-05 24.9 0.0 4.7e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 ORY53483.1 - 5.6e-05 23.5 0.1 0.00021 21.7 0.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase LEM PF03020.15 ORY53483.1 - 0.041 13.4 1.7 0.66 9.6 0.1 2.4 2 0 0 2 2 2 0 LEM domain HhH-GPD PF00730.25 ORY53484.1 - 9.3e-19 67.9 0.0 1.4e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein EndIII_4Fe-2S PF10576.9 ORY53484.1 - 4.6e-07 30.0 5.3 7.9e-07 29.2 5.3 1.4 1 0 0 1 1 1 1 Iron-sulfur binding domain of endonuclease III HHH PF00633.23 ORY53484.1 - 6.6e-06 25.7 0.4 4.2e-05 23.2 0.0 2.5 3 0 0 3 3 3 1 Helix-hairpin-helix motif DUF2400 PF09674.10 ORY53484.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Cas_GSU0053 PF09617.10 ORY53485.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) Lipase_GDSL PF00657.22 ORY53485.1 - 0.018 15.1 0.0 0.02 14.8 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase MTTB PF06253.11 ORY53486.1 - 0.0038 15.3 0.0 0.0045 15.0 0.0 1.0 1 0 0 1 1 1 1 Trimethylamine methyltransferase (MTTB) adh_short_C2 PF13561.6 ORY53487.1 - 2.8e-16 59.8 14.5 2.5e-11 43.6 2.7 3.0 2 1 1 3 3 3 3 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 ORY53487.1 - 9.2e-07 28.5 8.3 4.7e-05 22.9 1.0 2.0 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 ORY53487.1 - 0.0014 18.6 6.6 0.0031 17.5 6.6 1.6 1 1 0 1 1 1 1 KR domain CAP_N PF01213.19 ORY53487.1 - 0.027 13.9 0.3 0.046 13.2 0.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF1776 PF08643.10 ORY53487.1 - 0.038 13.4 0.0 0.05 13.0 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Usp PF00582.26 ORY53489.1 - 3.7e-18 66.4 0.0 4.6e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family DUF4744 PF15918.5 ORY53489.1 - 0.096 13.5 0.7 0.24 12.3 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4744) Ank_4 PF13637.6 ORY53490.1 - 9.5e-07 29.3 0.0 0.2 12.3 0.0 3.8 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Bacteriocin_IIi PF11758.8 ORY53490.1 - 0.043 13.6 0.1 0.043 13.6 0.1 3.6 5 0 0 5 5 5 0 Aureocin-like type II bacteriocin Prp19 PF08606.11 ORY53491.1 - 4.5e-31 106.6 3.3 1.2e-30 105.2 3.3 1.8 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 ORY53491.1 - 6.4e-20 71.1 13.8 0.00019 22.2 0.2 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY53491.1 - 2.6e-07 30.8 1.5 0.056 13.8 0.0 4.5 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TMF_TATA_bd PF12325.8 ORY53491.1 - 0.048 13.9 1.3 0.19 12.0 1.2 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Nup160 PF11715.8 ORY53491.1 - 0.13 10.9 0.5 15 4.0 0.0 3.1 2 1 2 4 4 4 0 Nucleoporin Nup120/160 zf-Nse PF11789.8 ORY53491.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DivIC PF04977.15 ORY53491.1 - 0.74 9.6 3.2 1.5 8.6 3.2 1.4 1 0 0 1 1 1 0 Septum formation initiator BTG PF07742.12 ORY53492.1 - 4.2e-25 87.8 0.0 9.9e-25 86.6 0.0 1.6 1 1 1 2 2 2 1 BTG family IncE PF17627.2 ORY53493.1 - 0.84 9.7 8.4 0.059 13.4 3.2 1.8 2 0 0 2 2 2 0 Inclusion membrane protein E DUF4006 PF13179.6 ORY53496.1 - 0.033 14.1 1.6 0.58 10.1 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF4006) RPAP2_Rtr1 PF04181.13 ORY53497.1 - 3.8e-19 68.8 0.3 9.3e-19 67.5 0.3 1.7 1 0 0 1 1 1 1 Rtr1/RPAP2 family BING4CT PF08149.11 ORY53498.1 - 2.7e-39 132.8 0.0 1.5e-35 120.8 0.0 3.2 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.32 ORY53498.1 - 1.1e-07 32.4 0.0 0.0079 17.0 0.0 6.2 7 1 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY53498.1 - 4.2e-06 27.0 0.0 4.9 7.5 0.0 5.1 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 ORY53498.1 - 0.00025 20.2 0.0 0.00055 19.1 0.0 1.5 1 1 0 1 1 1 1 Coatomer WD associated region WD40_like PF17005.5 ORY53498.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 WD40-like domain MFS_1 PF07690.16 ORY53499.1 - 9.5e-43 146.5 48.1 9.5e-43 146.5 48.1 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 ORY53499.1 - 6.7e-12 45.0 11.4 6.7e-12 45.0 11.4 3.0 2 1 0 3 3 3 2 Sugar (and other) transporter ABC_tran PF00005.27 ORY53502.1 - 3.4e-27 95.6 0.1 5.9e-27 94.9 0.1 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 ORY53502.1 - 2e-07 30.7 12.3 5.1e-07 29.3 12.3 1.7 1 0 0 1 1 1 1 ABC-2 type transporter RsgA_GTPase PF03193.16 ORY53502.1 - 0.00015 21.7 0.1 0.00028 20.8 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 ORY53502.1 - 0.0039 16.3 0.1 0.0084 15.2 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein RNA_helicase PF00910.22 ORY53502.1 - 0.0046 17.3 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_29 PF13555.6 ORY53502.1 - 0.0098 15.6 0.3 0.024 14.4 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 ORY53502.1 - 0.037 14.1 0.1 0.081 13.0 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 ORY53502.1 - 0.037 13.7 0.1 0.084 12.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ORY53502.1 - 0.045 14.3 0.1 0.084 13.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 ORY53502.1 - 0.054 13.1 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 ORY53502.1 - 0.061 12.9 0.0 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 ORY53502.1 - 0.061 12.8 2.6 0.14 11.6 0.3 2.3 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 ORY53502.1 - 0.07 13.4 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 ORY53502.1 - 0.078 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 ORY53502.1 - 0.082 12.7 0.7 7.6 6.2 0.0 2.3 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 ORY53502.1 - 0.12 12.7 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Glyco_transf_17 PF04724.13 ORY53503.1 - 8.4e-41 140.2 0.0 1.3e-40 139.5 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase family 17 DUF5499 PF17603.2 ORY53504.1 - 0.047 14.3 0.3 0.05 14.2 0.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5499) Talin_middle PF09141.10 ORY53505.1 - 0.016 15.2 0.6 0.018 15.1 0.6 1.1 1 0 0 1 1 1 0 Talin, middle domain Gelsolin PF00626.22 ORY53506.1 - 2.5e-08 33.7 0.0 0.00057 19.7 0.0 2.8 2 0 0 2 2 2 2 Gelsolin repeat TM_PBP2_N PF16296.5 ORY53507.1 - 0.14 12.3 0.1 0.53 10.5 0.1 2.0 2 0 0 2 2 2 0 N-terminal of TM subunit in PBP-dependent ABC transporters Glyco_transf_43 PF03360.16 ORY53508.1 - 0.00038 20.3 0.1 0.93 9.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 43 GDP_Man_Dehyd PF16363.5 ORY53509.1 - 2.9e-48 165.0 0.1 1.3e-47 162.8 0.1 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 ORY53509.1 - 3e-48 164.4 0.0 3.7e-48 164.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 ORY53509.1 - 6e-25 87.8 0.0 8.9e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 ORY53509.1 - 2.2e-15 56.6 0.2 1.2e-14 54.1 0.2 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 ORY53509.1 - 2.7e-11 43.2 1.1 6.5e-09 35.3 0.3 3.0 2 1 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 ORY53509.1 - 7.5e-10 39.0 0.0 1.3e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 ORY53509.1 - 4.5e-08 32.5 0.0 6.7e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 ORY53509.1 - 3.6e-05 23.3 0.0 9.2e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 ORY53509.1 - 0.0015 18.2 0.1 0.0034 17.0 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family HD_3 PF13023.6 ORY53509.1 - 0.0069 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 HD domain KR PF08659.10 ORY53509.1 - 0.2 11.6 0.6 1.8 8.4 0.6 2.1 1 1 0 1 1 1 0 KR domain DUF382 PF04037.13 ORY53510.1 - 2.1e-60 202.5 2.8 4.8e-60 201.3 2.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.16 ORY53510.1 - 3.7e-18 65.1 1.2 8.1e-18 64.0 1.2 1.6 1 0 0 1 1 1 1 PSP CDC45 PF02724.14 ORY53510.1 - 9.5 4.4 13.7 0.79 7.9 2.8 2.5 2 0 0 2 2 2 0 CDC45-like protein MCM_bind PF09739.9 ORY53512.1 - 0.082 11.3 6.5 0.13 10.7 6.5 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor NPR3 PF03666.13 ORY53512.1 - 0.7 8.6 6.2 1 8.1 6.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Mucin PF01456.17 ORY53514.1 - 9.5 6.2 20.1 21 5.1 20.1 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Tk-SP_N-pro PF18237.1 ORY53515.1 - 0.17 12.0 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Tk-SP N-propeptide domain Rax2 PF12768.7 ORY53517.1 - 0.083 12.3 0.1 3.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Cortical protein marker for cell polarity Cellulase PF00150.18 ORY53518.1 - 0.0056 16.1 0.1 0.021 14.2 0.1 1.8 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Ribosomal_S3_C PF00189.20 ORY53520.1 - 0.0016 18.9 0.0 0.002 18.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain RseC_MucC PF04246.12 ORY53521.1 - 0.049 13.6 0.5 0.19 11.6 0.1 2.1 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC ERG4_ERG24 PF01222.17 ORY53522.1 - 1.5e-96 323.8 19.0 1.7e-96 323.7 19.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 ORY53522.1 - 0.0011 18.6 0.1 0.0026 17.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 ORY53522.1 - 0.072 13.5 0.1 0.21 12.1 0.1 1.8 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family TMF_DNA_bd PF12329.8 ORY53523.1 - 0.011 15.8 4.2 0.011 15.8 4.2 6.9 3 1 5 8 8 8 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 ORY53524.1 - 0.0052 17.0 2.2 0.0052 17.0 2.2 3.1 2 1 1 3 3 3 2 Autophagy protein 16 (ATG16) ADIP PF11559.8 ORY53524.1 - 0.01 15.9 6.4 0.01 15.9 6.4 3.9 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding Mur_ligase PF01225.25 ORY53524.1 - 0.07 13.5 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 Mur ligase family, catalytic domain HOOK PF05622.12 ORY53524.1 - 0.081 11.1 38.2 0.26 9.4 12.6 3.1 2 1 1 3 3 3 0 HOOK protein SMAP PF15477.6 ORY53524.1 - 1.2 10.1 8.0 0.7 10.9 0.2 3.0 2 1 0 2 2 2 0 Small acidic protein family Spc7 PF08317.11 ORY53524.1 - 2.1 7.1 40.2 2.6 6.9 5.7 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein KASH_CCD PF14662.6 ORY53524.1 - 3.8 7.3 42.3 0.21 11.4 19.3 3.3 2 1 1 3 3 3 0 Coiled-coil region of CCDC155 or KASH IQ PF00612.27 ORY53525.1 - 3.6e-09 35.6 15.1 0.0029 17.3 0.3 3.8 4 0 0 4 4 4 3 IQ calmodulin-binding motif Utp11 PF03998.13 ORY53526.1 - 1.6e-67 228.0 33.0 1.8e-67 227.8 33.0 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 ORY53526.1 - 0.16 11.3 2.1 0.18 11.1 0.7 1.7 1 1 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Peptidase_S8 PF00082.22 ORY53528.1 - 7.6e-46 156.7 5.0 1.1e-45 156.2 5.0 1.2 1 0 0 1 1 1 1 Subtilase family PA PF02225.22 ORY53528.1 - 8.9e-07 28.9 1.7 1.8e-06 27.9 0.5 2.2 2 0 0 2 2 2 1 PA domain fn3_5 PF06280.12 ORY53528.1 - 1.4e-06 29.0 1.3 3.8e-06 27.6 1.3 1.8 1 1 0 1 1 1 1 Fn3-like domain NPCBM_assoc PF10633.9 ORY53528.1 - 0.035 14.4 0.1 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase SIP1 PF04938.12 ORY53529.1 - 1.5e-37 129.5 0.2 1.9e-37 129.1 0.2 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) p450 PF00067.22 ORY53530.1 - 3.9e-81 273.1 0.1 4.7e-81 272.9 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 C2 PF00168.30 ORY53531.1 - 8.5e-90 295.8 1.9 3.7e-17 62.5 0.0 6.5 6 0 0 6 6 6 6 C2 domain DIOX_N PF14226.6 ORY53532.1 - 1.3e-19 71.1 0.0 5e-19 69.2 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 ORY53532.1 - 5.3e-15 55.8 0.0 1e-14 54.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ABC_tran PF00005.27 ORY53533.1 - 1.2e-27 97.1 0.0 2.3e-27 96.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 ORY53533.1 - 2.6e-08 33.5 10.4 6.4e-08 32.3 10.4 1.6 1 0 0 1 1 1 1 ABC-2 type transporter RsgA_GTPase PF03193.16 ORY53533.1 - 0.00014 21.8 0.1 0.00029 20.8 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 ORY53533.1 - 0.0082 15.2 0.1 0.016 14.3 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 ORY53533.1 - 0.0089 15.7 0.4 0.022 14.5 0.4 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.6 ORY53533.1 - 0.025 14.3 0.1 0.044 13.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 ORY53533.1 - 0.026 15.0 0.2 0.062 13.8 0.2 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 ORY53533.1 - 0.027 14.5 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 ORY53533.1 - 0.031 14.6 0.2 0.1 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 ORY53533.1 - 0.035 14.5 0.0 0.071 13.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 ORY53533.1 - 0.075 12.7 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 ORY53533.1 - 0.091 13.1 0.1 0.27 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_10 PF12846.7 ORY53533.1 - 0.12 11.3 0.1 0.19 10.6 0.1 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_25 PF13481.6 ORY53533.1 - 0.18 11.3 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 ORY53533.1 - 0.25 10.8 0.4 1.1 8.6 0.4 2.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain TrwB_AAD_bind PF10412.9 ORY53533.1 - 0.75 8.6 2.3 2.2 7.1 0.2 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain UDPGP PF01704.18 ORY53534.1 - 5.5e-53 180.1 0.0 7.4e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 ORY53534.1 - 0.052 13.9 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain DUF1202 PF06717.11 ORY53536.1 - 0.069 12.6 3.8 0.08 12.3 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) Ku PF02735.16 ORY53537.1 - 8.5e-33 113.8 0.0 1.7e-32 112.8 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 ORY53537.1 - 8.3e-26 90.5 0.0 2.2e-25 89.1 0.0 1.8 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.15 ORY53537.1 - 4.9e-16 59.2 0.0 4.2e-15 56.1 0.0 2.1 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 ORY53537.1 - 7e-08 33.1 0.1 1.6e-07 31.9 0.1 1.6 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm PsbU PF06514.11 ORY53537.1 - 0.025 14.5 0.0 0.058 13.4 0.0 1.6 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) Zn_clus PF00172.18 ORY53538.1 - 2.9e-05 24.1 24.6 0.019 15.0 9.7 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 ORY53538.1 - 0.016 14.3 0.3 0.031 13.3 0.3 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF1279 PF06916.13 ORY53539.1 - 3.9e-05 24.1 0.0 6.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF4083 PF13314.6 ORY53540.1 - 0.27 11.2 0.4 0.72 9.8 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) 7tm_3 PF00003.22 ORY53541.1 - 1.2e-14 54.6 14.3 1.9e-14 54.0 14.3 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR CrgA PF06781.12 ORY53541.1 - 0.12 12.5 1.0 0.31 11.1 1.0 1.7 1 0 0 1 1 1 0 Cell division protein CrgA ANF_receptor PF01094.28 ORY53542.1 - 7.3e-08 31.9 0.0 1.1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY53542.1 - 1.6e-05 24.8 0.0 2.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein FMN_red PF03358.15 ORY53543.1 - 3e-25 88.8 0.0 2.4e-24 85.8 0.0 1.9 2 0 0 2 2 2 1 NADPH-dependent FMN reductase UDPGT PF00201.18 ORY53544.1 - 0.0002 20.3 0.1 0.00043 19.2 0.1 1.4 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Ribosomal_S11 PF00411.19 ORY53545.1 - 3.4e-42 143.3 1.4 4.3e-42 143.0 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 ORY53545.1 - 0.13 12.5 0.1 1.3 9.3 0.1 2.0 1 1 1 2 2 2 0 Carbohydrate binding domain (family 25) Synaptobrevin PF00957.21 ORY53546.1 - 9.7e-11 41.3 0.0 1.6e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF2207 PF09972.9 ORY53546.1 - 0.086 11.6 0.0 0.098 11.4 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DEC-1_N PF04625.13 ORY53546.1 - 0.087 11.8 6.7 0.12 11.3 6.7 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SRRM_C PF15230.6 ORY53547.1 - 0.041 14.5 0.0 0.06 13.9 0.0 1.3 1 0 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus NAD_binding_1 PF00175.21 ORY53549.1 - 2.6e-15 57.0 0.0 8.4e-14 52.1 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 ORY53549.1 - 5e-13 49.5 0.1 2.9e-12 47.0 0.0 2.1 2 1 0 2 2 2 1 Ferric reductase NAD binding domain DUF3043 PF11241.8 ORY53551.1 - 9.7 6.2 5.8 2 8.4 2.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3043) PHD PF00628.29 ORY53552.1 - 0.0014 18.5 4.7 0.0014 18.5 4.7 1.6 2 0 0 2 2 2 1 PHD-finger NOA36 PF06524.12 ORY53552.1 - 0.0024 17.3 5.4 0.0032 16.8 5.4 1.1 1 0 0 1 1 1 1 NOA36 protein zf-B_box PF00643.24 ORY53552.1 - 1.3 9.3 13.0 0.58 10.4 1.7 2.3 2 0 0 2 2 2 0 B-box zinc finger SNF2_N PF00176.23 ORY53553.1 - 1.2e-48 165.6 0.0 6.9e-48 163.1 0.0 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 ORY53553.1 - 4.8e-12 46.2 0.0 2.6e-11 43.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 ORY53553.1 - 3.1e-05 24.0 0.0 8.6e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 ORY53553.1 - 0.046 12.9 0.0 6.7 5.8 0.0 2.3 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 DUF4203 PF13886.6 ORY53554.1 - 3.8e-32 111.6 34.2 3.8e-32 111.6 34.2 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) WD40 PF00400.32 ORY53555.1 - 1.9e-20 72.8 19.0 4.6e-05 24.1 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY53555.1 - 2.6e-14 53.3 5.1 6e-07 29.7 0.3 4.8 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 ORY53555.1 - 0.0078 15.2 0.1 0.24 10.3 0.1 2.8 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANF_receptor PF01094.28 ORY53556.1 - 1.1e-18 67.5 0.1 1.2e-18 67.4 0.1 1.0 1 0 0 1 1 1 1 Receptor family ligand binding region Peripla_BP_6 PF13458.6 ORY53556.1 - 0.00072 19.3 2.0 0.0011 18.8 2.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein 7tm_3 PF00003.22 ORY53557.1 - 2.5e-15 56.9 9.0 3.9e-15 56.2 9.0 1.3 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR 7TMR-DISM_7TM PF07695.11 ORY53557.1 - 0.0028 17.6 1.1 0.0028 17.6 1.1 2.6 1 1 2 3 3 3 1 7TM diverse intracellular signalling Mycobact_memb PF05423.13 ORY53557.1 - 0.092 12.7 0.0 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 Mycobacterium membrane protein DUF4389 PF14333.6 ORY53557.1 - 0.79 9.7 4.9 2.2 8.2 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4389) CEP19 PF14933.6 ORY53558.1 - 2.6e-31 109.2 0.1 3.3e-31 108.8 0.1 1.1 1 0 0 1 1 1 1 CEP19-like protein HECT PF00632.25 ORY53559.1 - 3.4e-27 95.7 0.1 3.7e-27 95.6 0.1 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Vps16_C PF04840.12 ORY53559.1 - 0.035 13.1 0.0 0.04 12.9 0.0 1.0 1 0 0 1 1 1 0 Vps16, C-terminal region HECT PF00632.25 ORY53560.1 - 2.7e-19 69.8 0.0 4.7e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.25 ORY53561.1 - 6.3e-55 186.4 3.5 1.6e-54 185.0 0.5 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY53561.1 - 1.5e-27 96.5 1.1 3.6e-27 95.3 0.1 2.0 3 1 0 3 3 3 1 Protein tyrosine kinase KA1 PF02149.19 ORY53561.1 - 6.3e-17 61.1 0.1 1.1e-16 60.3 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Haspin_kinase PF12330.8 ORY53561.1 - 0.075 12.0 0.2 0.15 11.0 0.2 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Thioredoxin_14 PF18402.1 ORY53561.1 - 0.087 12.8 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain Kdo PF06293.14 ORY53561.1 - 0.087 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSF_DNA-bind PF00447.17 ORY53562.1 - 1.3e-28 99.5 4.2 1.3e-28 99.5 4.2 2.3 2 1 0 2 2 2 1 HSF-type DNA-binding APG6_N PF17675.1 ORY53562.1 - 0.0042 17.6 0.4 0.015 15.8 0.0 2.0 2 0 0 2 2 2 1 Apg6 coiled-coil region Phage_lysis PF03245.13 ORY53562.1 - 0.0087 16.2 1.9 0.017 15.3 1.9 1.4 1 0 0 1 1 1 1 Bacteriophage Rz lysis protein Ets PF00178.22 ORY53562.1 - 0.027 14.9 0.9 0.44 11.0 0.1 2.5 2 1 0 2 2 2 0 Ets-domain KxDL PF10241.9 ORY53562.1 - 0.068 13.4 4.4 0.19 12.0 4.4 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein Tropomyosin PF00261.20 ORY53562.1 - 0.069 12.5 1.6 0.1 11.9 1.6 1.2 1 0 0 1 1 1 0 Tropomyosin DUF3246 PF11596.8 ORY53562.1 - 0.094 12.1 3.2 0.15 11.5 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DUF3391 PF11871.8 ORY53562.1 - 0.095 13.2 1.8 12 6.4 0.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Sec8_exocyst PF04048.14 ORY53562.1 - 0.15 11.9 2.2 0.24 11.3 1.3 1.7 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF1664 PF07889.12 ORY53562.1 - 0.35 10.9 1.4 0.72 9.9 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 ORY53562.1 - 0.76 9.0 6.5 1.2 8.4 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) bZIP_1 PF00170.21 ORY53563.1 - 4.7e-07 29.8 5.5 6.8e-06 26.1 3.7 2.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 ORY53563.1 - 0.018 15.1 3.4 0.018 15.1 3.4 2.4 2 0 0 2 2 2 0 Basic region leucine zipper CK2S PF15011.6 ORY53563.1 - 0.037 13.9 1.2 0.077 12.9 0.5 1.9 2 1 0 2 2 2 0 Casein Kinase 2 substrate DivIC PF04977.15 ORY53563.1 - 0.16 11.8 4.9 2.8 7.8 0.1 2.5 2 0 0 2 2 2 0 Septum formation initiator LPP PF04728.13 ORY53563.1 - 0.17 12.3 1.3 30 5.1 0.2 2.9 2 1 0 2 2 2 0 Lipoprotein leucine-zipper FlxA PF14282.6 ORY53563.1 - 1.2 9.1 4.2 5.4 7.1 0.2 2.8 2 1 0 2 2 2 0 FlxA-like protein FSH1 PF03959.13 ORY53564.1 - 1.3e-11 44.6 0.0 1.8e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) G-alpha PF00503.20 ORY53565.1 - 4.8e-58 197.0 14.7 1.8e-56 191.8 14.7 2.4 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 ORY53565.1 - 5.8e-08 32.4 4.8 0.0034 16.9 0.7 2.7 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 ORY53565.1 - 0.0018 17.7 4.9 0.0042 16.5 1.4 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 ORY53565.1 - 0.0035 16.9 0.1 0.54 9.8 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 ORY53565.1 - 0.0076 16.0 0.7 0.027 14.2 0.5 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein DAP3 PF10236.9 ORY53565.1 - 0.062 12.4 0.4 0.13 11.4 0.4 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_18 PF13238.6 ORY53565.1 - 0.091 13.3 0.0 0.35 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain KdpC PF02669.15 ORY53566.1 - 0.23 11.3 1.1 0.68 9.8 0.1 2.0 2 0 0 2 2 2 0 K+-transporting ATPase, c chain Lig_chan PF00060.26 ORY53566.1 - 2.7 7.8 7.6 0.13 12.1 1.1 2.0 2 0 0 2 2 2 0 Ligand-gated ion channel zf-MYND PF01753.18 ORY53567.1 - 0.062 13.4 10.2 0.14 12.3 10.2 1.6 1 0 0 1 1 1 0 MYND finger Spo0M PF07070.11 ORY53570.1 - 0.023 14.2 0.0 0.027 14.0 0.0 1.1 1 0 0 1 1 1 0 SpoOM protein Spo0M PF07070.11 ORY53572.1 - 0.00045 19.8 1.1 0.0011 18.5 1.1 1.6 1 1 0 1 1 1 1 SpoOM protein Arrestin_N PF00339.29 ORY53572.1 - 0.011 15.8 0.1 0.025 14.7 0.1 1.5 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain LRR_4 PF12799.7 ORY53574.1 - 8.9e-17 60.9 2.9 4.3e-08 33.3 0.3 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 ORY53574.1 - 2.1e-10 40.4 0.4 8e-05 22.2 0.1 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 ORY53574.1 - 5.6e-10 38.8 7.7 1.2e-06 28.2 1.9 3.4 3 1 1 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 ORY53574.1 - 0.042 13.9 4.8 3.9 7.8 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich repeat Pkinase PF00069.25 ORY53575.1 - 5.2e-66 222.7 0.0 6.5e-66 222.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY53575.1 - 1.3e-34 119.7 0.0 1.5e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 ORY53575.1 - 1.3e-06 27.5 0.0 2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY53575.1 - 4.1e-06 26.3 0.0 5.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 ORY53575.1 - 0.00036 19.6 0.0 0.00054 19.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY53575.1 - 0.00074 18.9 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY53575.1 - 0.065 13.1 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 ORY53576.1 - 3.9e-27 95.3 0.0 4.2e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY53576.1 - 3.4e-13 49.5 0.0 3.7e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 ORY53576.1 - 5.2e-05 22.7 0.0 5.6e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY53576.1 - 0.00017 20.7 0.0 0.00019 20.5 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 ORY53576.1 - 0.0035 16.2 0.0 0.0043 15.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 ORY53576.1 - 0.0036 16.7 0.0 0.0036 16.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 ORY53576.1 - 0.018 15.0 0.0 0.018 15.0 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 ORY53576.1 - 0.18 10.7 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF4407 PF14362.6 ORY53577.1 - 0.88 8.9 6.7 0.53 9.6 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Allexi_40kDa PF05549.11 ORY53577.1 - 1.3 8.5 8.3 0.15 11.5 1.6 2.3 2 0 0 2 2 2 0 Allexivirus 40kDa protein ZapB PF06005.12 ORY53577.1 - 4.6 7.7 18.8 0.27 11.7 1.0 2.7 2 0 0 2 2 2 0 Cell division protein ZapB PHO4 PF01384.20 ORY53578.1 - 2.5e-99 332.5 23.9 3.3e-99 332.2 23.9 1.1 1 0 0 1 1 1 1 Phosphate transporter family Bacteriocin_IIi PF11758.8 ORY53578.1 - 0.024 14.4 0.6 0.073 12.9 0.6 1.8 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin S_4TM PF18159.1 ORY53578.1 - 0.47 9.7 1.7 1.2 8.3 1.7 1.7 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain DUF5046 PF16465.5 ORY53579.1 - 0.09 12.2 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5046) WD40 PF00400.32 ORY53581.1 - 0.11 13.4 0.1 7.1 7.7 0.0 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat GDPD PF03009.17 ORY53581.1 - 0.18 11.5 0.0 0.24 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family WD40 PF00400.32 ORY53582.1 - 1.2e-12 48.1 1.9 0.00035 21.3 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY53582.1 - 0.00019 21.7 0.0 0.64 10.4 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 ORY53582.1 - 0.0045 17.4 0.1 15 6.2 0.0 4.1 4 0 0 4 4 4 1 PQQ-like domain cobW PF02492.19 ORY53582.1 - 0.076 12.6 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain tRNA-synt_1c_C PF03950.18 ORY53582.1 - 0.21 11.4 2.8 0.56 10.1 1.9 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), anti-codon binding domain FAM76 PF16046.5 ORY53582.1 - 5 6.4 7.9 7.9 5.7 7.9 1.2 1 0 0 1 1 1 0 FAM76 protein ATG16 PF08614.11 ORY53583.1 - 9.3e-08 32.5 15.3 0.0012 19.1 8.4 2.2 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 ORY53583.1 - 4e-05 23.5 28.1 0.0036 17.1 19.6 2.6 1 1 2 3 3 3 2 Coiled-coil region of CCDC155 or KASH DUF4763 PF15960.5 ORY53583.1 - 0.00011 21.6 11.8 0.00011 21.6 11.8 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4763) FPP PF05911.11 ORY53583.1 - 0.00014 20.2 21.6 0.00018 19.9 21.6 1.2 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Tropomyosin_1 PF12718.7 ORY53583.1 - 0.0013 18.9 21.6 0.0013 18.9 21.6 2.6 2 1 0 2 2 2 1 Tropomyosin like MPS2 PF17060.5 ORY53583.1 - 0.0013 18.0 18.2 0.0065 15.8 13.1 2.3 1 1 1 2 2 2 1 Monopolar spindle protein 2 FlxA PF14282.6 ORY53583.1 - 0.0016 18.4 21.1 0.089 12.8 1.4 3.3 2 1 1 3 3 3 2 FlxA-like protein FliJ PF02050.16 ORY53583.1 - 0.0017 18.6 21.0 0.05 13.8 13.1 2.7 2 1 1 3 3 3 2 Flagellar FliJ protein ADIP PF11559.8 ORY53583.1 - 0.003 17.6 30.3 0.022 14.8 9.6 3.1 1 1 2 3 3 3 2 Afadin- and alpha -actinin-Binding TACC_C PF05010.14 ORY53583.1 - 0.0032 17.3 29.4 0.05 13.4 18.3 2.2 1 1 1 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Filament PF00038.21 ORY53583.1 - 0.0064 16.1 28.9 0.011 15.3 3.7 2.5 1 1 1 2 2 2 1 Intermediate filament protein Taxilin PF09728.9 ORY53583.1 - 0.0074 15.5 26.9 0.7 9.0 26.9 2.2 1 1 0 1 1 1 1 Myosin-like coiled-coil protein GAS PF13851.6 ORY53583.1 - 0.0087 15.4 19.0 0.0087 15.4 19.0 2.9 1 1 2 3 3 3 2 Growth-arrest specific micro-tubule binding E2R135 PF11570.8 ORY53583.1 - 0.0095 16.2 8.4 0.034 14.4 6.9 2.2 1 1 1 2 2 2 1 Coiled-coil receptor-binding R-domain of colicin E2 CENP-F_leu_zip PF10473.9 ORY53583.1 - 0.013 15.6 30.2 0.014 15.4 11.7 2.9 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 ORY53583.1 - 0.013 14.4 30.1 0.35 9.7 8.4 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 ORY53583.1 - 0.014 15.9 27.9 0.12 12.9 3.6 2.3 1 1 1 2 2 2 0 Fez1 Laminin_II PF06009.12 ORY53583.1 - 0.016 15.2 5.0 0.016 15.2 5.0 2.7 2 1 1 3 3 3 0 Laminin Domain II Fib_alpha PF08702.10 ORY53583.1 - 0.028 14.6 20.2 0.23 11.6 5.9 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family FAM76 PF16046.5 ORY53583.1 - 0.031 13.7 25.7 0.016 14.6 12.8 2.4 1 1 1 2 2 2 0 FAM76 protein UPF0242 PF06785.11 ORY53583.1 - 0.032 14.3 31.3 0.04 14.0 14.9 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Clr5 PF14420.6 ORY53583.1 - 0.039 14.2 1.3 0.039 14.2 1.3 2.3 2 1 0 2 2 1 0 Clr5 domain DUF4407 PF14362.6 ORY53583.1 - 0.061 12.7 16.0 0.049 13.0 8.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4094 PF13334.6 ORY53583.1 - 0.093 13.2 11.4 1.1 9.7 1.2 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) Sec8_exocyst PF04048.14 ORY53583.1 - 0.095 12.6 13.7 0.036 14.0 5.1 3.0 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain Myosin_tail_1 PF01576.19 ORY53583.1 - 0.097 10.5 34.6 0.12 10.2 34.6 1.1 1 0 0 1 1 1 0 Myosin tail AAA_13 PF13166.6 ORY53583.1 - 0.11 11.1 25.5 0.3 9.7 25.5 1.7 1 1 0 1 1 1 0 AAA domain DUF1664 PF07889.12 ORY53583.1 - 0.12 12.5 16.8 0.33 11.0 2.9 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF1460 PF07313.12 ORY53583.1 - 0.14 11.6 4.6 0.22 10.9 4.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1460) TMF_DNA_bd PF12329.8 ORY53583.1 - 0.15 12.0 39.0 0.11 12.5 12.0 4.2 2 1 3 5 5 5 0 TATA element modulatory factor 1 DNA binding Atg14 PF10186.9 ORY53583.1 - 0.16 11.0 24.0 0.7 8.9 9.7 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 ORY53583.1 - 0.17 12.5 25.2 0.065 13.9 3.6 3.3 1 1 0 2 2 2 0 Initiation control protein YabA DUF812 PF05667.11 ORY53583.1 - 0.2 10.5 27.5 9.7 4.9 26.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF641 PF04859.12 ORY53583.1 - 0.26 11.6 23.6 0.8 10.0 12.8 3.8 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) DUF3450 PF11932.8 ORY53583.1 - 0.28 10.4 20.7 0.068 12.5 4.9 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF3450) HrpB7 PF09486.10 ORY53583.1 - 0.28 11.5 13.0 0.26 11.6 4.0 2.7 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) CSN5_C PF18323.1 ORY53583.1 - 0.32 11.9 0.1 0.32 11.9 0.1 3.4 1 1 1 2 2 1 0 Cop9 signalosome subunit 5 C-terminal domain BST2 PF16716.5 ORY53583.1 - 0.37 11.4 21.6 0.058 14.0 1.8 4.0 1 1 3 4 4 4 0 Bone marrow stromal antigen 2 Cep57_MT_bd PF06657.13 ORY53583.1 - 0.41 11.1 24.0 0.18 12.3 5.3 4.0 2 1 2 4 4 3 0 Centrosome microtubule-binding domain of Cep57 TMF_TATA_bd PF12325.8 ORY53583.1 - 0.54 10.5 26.5 0.044 14.0 6.9 3.7 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding FlaC_arch PF05377.11 ORY53583.1 - 0.76 10.2 11.1 18 5.8 0.1 4.4 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 ORY53583.1 - 0.81 9.5 35.0 0.12 12.2 1.3 4.9 1 1 3 5 5 5 0 Septum formation initiator HMMR_N PF15905.5 ORY53583.1 - 0.81 9.1 33.8 0.079 12.4 22.4 2.7 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal MAD PF05557.13 ORY53583.1 - 0.82 8.0 29.1 1.4 7.2 29.1 1.4 1 1 0 1 1 1 0 Mitotic checkpoint protein PI3K_P85_iSH2 PF16454.5 ORY53583.1 - 1.2 8.7 28.0 2.9 7.5 4.6 2.6 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain CALCOCO1 PF07888.11 ORY53583.1 - 1.5 7.6 26.7 0.083 11.7 18.6 2.2 1 1 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4200 PF13863.6 ORY53583.1 - 1.7 9.1 40.8 2.8 8.4 0.3 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) DUF2203 PF09969.9 ORY53583.1 - 1.7 9.4 19.5 38 5.0 9.3 3.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) OmpH PF03938.14 ORY53583.1 - 1.7 9.0 34.6 0.12 12.7 11.8 3.5 1 1 2 3 3 2 0 Outer membrane protein (OmpH-like) APG6_N PF17675.1 ORY53583.1 - 1.9 9.0 34.1 5.8e+03 -2.3 34.1 3.2 1 1 0 1 1 0 0 Apg6 coiled-coil region HemX PF04375.14 ORY53583.1 - 1.9 7.7 11.8 36 3.5 11.9 2.2 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase CC2-LZ PF16516.5 ORY53583.1 - 2 8.8 28.3 0.92 9.9 0.8 4.0 1 1 4 5 5 5 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4201 PF13870.6 ORY53583.1 - 2.1 8.1 34.3 0.48 10.1 6.4 3.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4201) Rho_Binding PF08912.11 ORY53583.1 - 2.2 9.1 34.7 1.4 9.8 5.8 4.8 3 1 1 4 4 4 0 Rho Binding DUF724 PF05266.14 ORY53583.1 - 2.3 8.0 28.6 4 7.2 8.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF2968 PF11180.8 ORY53583.1 - 2.4 7.7 13.6 3.7 7.1 4.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) SseC PF04888.12 ORY53583.1 - 2.8 7.4 10.3 0.25 10.9 4.5 2.1 2 1 0 2 2 2 0 Secretion system effector C (SseC) like family TMCO5 PF14992.6 ORY53583.1 - 3.1 7.3 31.1 0.16 11.6 13.0 2.8 1 1 2 3 3 3 0 TMCO5 family Phage_GP20 PF06810.11 ORY53583.1 - 3.4 7.5 33.2 1.6 8.5 5.8 4.1 1 1 2 4 4 4 0 Phage minor structural protein GP20 DUF16 PF01519.16 ORY53583.1 - 4.4 7.8 24.0 2.7e+02 2.1 10.6 3.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 HAUS-augmin3 PF14932.6 ORY53583.1 - 5.3 6.5 21.9 0.46 10.0 11.2 2.4 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 TolA_bind_tri PF16331.5 ORY53583.1 - 5.5 7.1 10.2 15 5.8 1.1 3.6 2 2 1 3 3 3 0 TolA binding protein trimerisation V_ATPase_I PF01496.19 ORY53583.1 - 6.5 4.5 14.2 7.5 4.3 13.6 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Med9 PF07544.13 ORY53583.1 - 6.7 6.9 23.2 12 6.1 0.8 4.0 1 1 2 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 TPR_MLP1_2 PF07926.12 ORY53583.1 - 7.3 6.7 27.2 1.6 8.8 1.2 3.6 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc29 PF17082.5 ORY53583.1 - 9.6 6.0 12.8 2.9e+02 1.1 12.8 2.4 1 1 0 1 1 1 0 Spindle Pole Component 29 LMBR1 PF04791.16 ORY53583.1 - 9.9 4.9 8.5 11 4.8 8.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PHO4 PF01384.20 ORY53584.1 - 4e-115 384.5 20.9 6e-115 383.9 20.9 1.3 1 0 0 1 1 1 1 Phosphate transporter family Bacteriocin_IIi PF11758.8 ORY53584.1 - 0.011 15.6 1.2 0.028 14.2 1.2 1.7 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin HCV_NS5a_1a PF08300.13 ORY53584.1 - 0.024 14.7 0.2 2.5 8.3 0.0 2.7 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a zinc finger domain Dpy19 PF10034.9 ORY53584.1 - 0.031 12.5 1.7 0.057 11.6 1.7 1.3 1 0 0 1 1 1 0 Q-cell neuroblast polarisation DUF4017 PF13209.6 ORY53584.1 - 2.9 7.9 9.4 0.19 11.7 0.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4017) Lectin_leg-like PF03388.13 ORY53585.1 - 1.4e-54 184.9 0.0 1.9e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 ORY53585.1 - 2.1e-08 34.4 0.1 5e-08 33.2 0.0 1.6 2 0 0 2 2 2 1 Bacterial lectin T3SSipB PF16535.5 ORY53585.1 - 0.021 15.3 3.2 0.021 15.3 3.2 2.2 1 1 1 2 2 2 0 Type III cell invasion protein SipB BLOC1_2 PF10046.9 ORY53585.1 - 0.033 14.5 1.8 0.033 14.5 1.8 2.3 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 XhlA PF10779.9 ORY53585.1 - 0.034 14.3 2.2 2.2 8.6 0.2 2.9 3 0 0 3 3 3 0 Haemolysin XhlA Atg14 PF10186.9 ORY53585.1 - 0.057 12.5 4.5 0.079 12.0 4.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Laminin_II PF06009.12 ORY53585.1 - 0.059 13.4 10.2 0.021 14.8 5.2 2.5 1 1 2 3 3 3 0 Laminin Domain II UPF0184 PF03670.13 ORY53585.1 - 0.093 13.1 0.2 0.2 12.1 0.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) Helicase_PWI PF18149.1 ORY53585.1 - 0.11 12.7 0.5 0.24 11.6 0.5 1.5 1 0 0 1 1 1 0 N-terminal helicase PWI domain LYTB PF02401.18 ORY53585.1 - 0.14 11.4 1.0 0.58 9.4 0.3 1.9 1 1 1 2 2 2 0 LytB protein DUF2524 PF10732.9 ORY53585.1 - 0.18 12.1 2.7 0.51 10.7 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2524) DUF3138 PF11336.8 ORY53585.1 - 0.18 10.4 2.2 0.36 9.4 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) 5_nucleotid PF05761.14 ORY53585.1 - 0.24 10.2 1.3 0.36 9.7 1.3 1.2 1 0 0 1 1 1 0 5' nucleotidase family DUF2730 PF10805.8 ORY53585.1 - 0.28 11.3 1.7 1.3 9.2 0.2 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) DUF1664 PF07889.12 ORY53585.1 - 0.68 10.0 4.8 0.75 9.8 1.7 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Uds1 PF15456.6 ORY53585.1 - 1.1 9.5 7.2 9.1 6.5 0.7 3.1 2 1 1 3 3 3 0 Up-regulated During Septation Lebercilin PF15619.6 ORY53585.1 - 1.8 8.2 10.2 0.51 10.0 3.2 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 ORY53585.1 - 3 6.7 10.5 8.9 5.1 10.5 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein Snapin_Pallidin PF14712.6 ORY53585.1 - 3.9 8.0 11.1 0.36 11.3 0.3 2.8 2 1 1 3 3 3 0 Snapin/Pallidin DUF4473 PF14747.6 ORY53585.1 - 6.4 7.4 7.8 19 5.9 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4473) FAM76 PF16046.5 ORY53585.1 - 7 5.9 6.2 10 5.4 6.2 1.1 1 0 0 1 1 1 0 FAM76 protein NPV_P10 PF05531.12 ORY53585.1 - 9.5 6.8 7.0 5.7 7.5 1.7 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ClpS PF02617.17 ORY53586.1 - 0.0023 17.7 0.0 0.0036 17.0 0.0 1.5 1 1 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ERCC4 PF02732.15 ORY53589.1 - 2.1e-18 67.0 0.0 7.2e-18 65.3 0.0 1.9 2 0 0 2 2 2 1 ERCC4 domain Ank_2 PF12796.7 ORY53590.1 - 6.5e-06 26.6 0.0 4.1e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY53590.1 - 0.0012 19.1 0.1 0.08 13.3 0.1 2.7 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY53590.1 - 0.025 15.1 0.4 6.4 7.5 0.0 3.1 2 1 2 4 4 4 0 Ankyrin repeats (many copies) SPESP1 PF15754.5 ORY53590.1 - 0.1 11.8 0.0 10 5.2 0.0 2.2 2 0 0 2 2 2 0 Sperm equatorial segment protein 1 Pre-PUA PF17832.1 ORY53594.1 - 9.2e-10 39.1 0.0 5.3e-09 36.7 0.0 2.4 2 0 0 2 2 2 1 Pre-PUA-like domain SWIB PF02201.18 ORY53594.1 - 0.00058 19.7 0.0 0.0015 18.4 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain PUA PF01472.20 ORY53594.1 - 0.00066 19.6 0.1 0.0044 16.9 0.1 2.3 1 1 0 1 1 1 1 PUA domain Suc_Fer-like PF06999.12 ORY53596.1 - 1e-18 67.9 0.0 1.6e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Fer2 PF00111.27 ORY53596.1 - 6.6e-09 35.6 2.2 7.5e-09 35.4 0.5 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain MCR PF18509.1 ORY53596.1 - 0.023 14.3 0.3 0.041 13.5 0.3 1.4 1 0 0 1 1 1 0 Magnetochrome domain Cytochrom_B561 PF03188.16 ORY53597.1 - 2.7e-10 40.5 7.0 4.9e-10 39.7 7.0 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2053 PF09767.9 ORY53597.1 - 0.0056 16.8 0.2 0.0056 16.8 0.2 1.8 2 0 0 2 2 2 1 Predicted membrane protein (DUF2053) DUF4079 PF13301.6 ORY53597.1 - 0.039 14.1 1.8 0.062 13.5 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) DUF4271 PF14093.6 ORY53597.1 - 0.05 13.5 3.7 0.08 12.8 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) DUF2427 PF10348.9 ORY53597.1 - 0.39 10.5 5.2 0.073 12.9 1.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) Ank_2 PF12796.7 ORY53601.1 - 2.3e-17 63.3 0.0 2.6e-10 40.7 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY53601.1 - 1.1e-16 60.7 0.0 1.1e-07 31.9 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 ORY53601.1 - 3.6e-16 57.6 0.0 1.6e-07 31.0 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 ORY53601.1 - 4.9e-15 55.2 0.0 8.5e-06 26.0 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 ORY53601.1 - 9.8e-11 42.0 0.0 1.5e-06 28.6 0.0 2.3 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 ORY53602.1 - 1.7e-21 76.3 1.0 3.5e-07 30.6 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 ORY53602.1 - 6.6e-19 68.3 0.3 1.3e-10 41.7 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 ORY53602.1 - 1.4e-18 66.7 0.9 1.1e-10 41.5 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 ORY53602.1 - 9.8e-18 63.7 3.6 1.1e-05 25.6 0.1 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 ORY53602.1 - 1.4e-16 58.9 0.0 0.0008 19.7 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ribosomal_L6 PF00347.23 ORY53603.1 - 9.3e-28 96.7 1.0 1.4e-16 60.9 0.4 2.6 2 1 0 2 2 2 2 Ribosomal protein L6 Dus PF01207.17 ORY53604.1 - 1.1e-67 228.3 0.0 2.8e-67 227.0 0.0 1.4 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) NMO PF03060.15 ORY53604.1 - 0.004 16.6 0.0 0.036 13.5 0.0 1.9 1 1 1 2 2 2 1 Nitronate monooxygenase SOR_SNZ PF01680.17 ORY53604.1 - 0.014 15.2 0.0 1.1 9.0 0.0 2.1 1 1 1 2 2 2 0 SOR/SNZ family G3P_antiterm PF04309.12 ORY53604.1 - 0.025 14.0 0.0 0.047 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator His_biosynth PF00977.21 ORY53604.1 - 0.062 12.7 0.0 0.098 12.1 0.0 1.3 1 1 0 1 1 1 0 Histidine biosynthesis protein ThiG PF05690.14 ORY53604.1 - 0.064 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG DUF2362 PF10154.9 ORY53606.1 - 2.5e-51 175.2 2.2 1.4e-21 77.0 0.4 5.2 3 2 2 5 5 5 5 Uncharacterized conserved protein (DUF2362) UBA PF00627.31 ORY53606.1 - 0.00099 19.0 0.0 0.0024 17.8 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain TMEM132D_N PF15705.5 ORY53606.1 - 0.03 14.2 0.6 9.7 6.0 0.0 2.8 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term DUF155 PF02582.14 ORY53608.1 - 1.1e-05 25.7 0.1 1.8e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF155 PF02582.14 ORY53609.1 - 5e-31 108.1 0.1 6.2e-31 107.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Hydrolase PF00702.26 ORY53610.1 - 1.1e-07 32.4 0.0 1.6e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 ORY53610.1 - 8.4e-06 25.7 0.3 0.00027 20.8 1.0 2.1 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 ORY53611.1 - 4.4e-21 75.2 0.0 5.3e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 E1-E2 ATPase ABC_membrane PF00664.23 ORY53612.1 - 4.1e-65 220.2 27.4 1.5e-34 119.9 13.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 ORY53612.1 - 8e-48 162.4 0.0 2.5e-25 89.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 ORY53612.1 - 5.4e-08 32.9 1.5 0.0038 17.3 0.0 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 ORY53612.1 - 1.6e-07 31.0 2.8 0.021 14.3 0.2 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 ORY53612.1 - 5.3e-07 29.7 0.2 0.0022 17.9 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 ORY53612.1 - 6.7e-07 29.5 0.5 0.00061 19.9 0.0 2.3 2 0 0 2 2 2 2 Dynamin family AAA_21 PF13304.6 ORY53612.1 - 1.2e-06 28.5 0.2 0.097 12.5 0.1 3.7 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 ORY53612.1 - 1.7e-05 24.5 1.7 0.014 15.1 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY53612.1 - 8.4e-05 23.0 0.1 0.22 11.9 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain T2SSE PF00437.20 ORY53612.1 - 0.00021 20.4 0.1 0.0075 15.4 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 ORY53612.1 - 0.00031 21.0 0.1 0.44 10.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 ORY53612.1 - 0.00052 20.6 0.3 0.21 12.1 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 ORY53612.1 - 0.00086 19.1 0.4 0.78 9.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 ORY53612.1 - 0.00088 18.9 0.6 0.036 13.7 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 ORY53612.1 - 0.00098 19.3 2.0 0.11 12.6 0.0 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain FtsK_SpoIIIE PF01580.18 ORY53612.1 - 0.0063 15.9 1.6 1 8.6 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_15 PF13175.6 ORY53612.1 - 0.0094 15.7 0.7 0.55 9.9 0.6 2.2 2 0 0 2 2 2 1 AAA ATPase domain TrwB_AAD_bind PF10412.9 ORY53612.1 - 0.012 14.5 0.0 3.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.12 ORY53612.1 - 0.018 14.3 0.1 0.84 8.9 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_7 PF12775.7 ORY53612.1 - 0.021 14.4 0.2 2.6 7.5 0.0 2.6 3 0 0 3 3 2 0 P-loop containing dynein motor region DUF815 PF05673.13 ORY53612.1 - 0.024 13.8 0.0 0.8 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 ORY53612.1 - 0.025 14.3 0.1 2 8.1 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.14 ORY53612.1 - 0.036 13.3 0.0 0.95 8.6 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain NACHT PF05729.12 ORY53612.1 - 0.1 12.5 0.2 12 5.7 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Roc PF08477.13 ORY53612.1 - 0.11 12.7 0.1 8.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 ORY53612.1 - 0.16 11.0 0.2 15 4.5 0.0 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) MeaB PF03308.16 ORY53612.1 - 0.6 9.0 5.4 4.9 6.1 0.1 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 ORY53612.1 - 0.72 9.1 3.8 2.6 7.3 0.3 2.2 2 0 0 2 2 2 0 AIG1 family ABC_ATPase PF09818.9 ORY53612.1 - 1.1 8.0 4.3 2.1 7.1 0.1 2.5 3 0 0 3 3 3 0 Predicted ATPase of the ABC class Pex24p PF06398.11 ORY53612.1 - 2.4 7.0 5.9 0.23 10.4 0.6 1.9 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin VWA PF00092.28 ORY53615.1 - 0.029 14.6 0.0 2.4 8.4 0.0 2.9 2 1 1 3 3 3 0 von Willebrand factor type A domain VWA_CoxE PF05762.14 ORY53616.1 - 0.011 15.1 0.0 4.3 6.7 0.0 2.2 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein VWA PF00092.28 ORY53616.1 - 0.098 12.9 0.0 3.6 7.8 0.1 2.8 1 1 1 2 2 2 0 von Willebrand factor type A domain VWA PF00092.28 ORY53617.1 - 0.096 12.9 0.0 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 von Willebrand factor type A domain VWA_CoxE PF05762.14 ORY53617.1 - 0.11 11.8 0.0 12 5.2 0.0 2.2 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein DUF3431 PF11913.8 ORY53618.1 - 0.0031 17.3 0.1 0.0055 16.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF3431 PF11913.8 ORY53619.1 - 4.4e-09 36.4 3.7 1.4e-05 25.0 1.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3431) DUF1722 PF08349.11 ORY53619.1 - 0.012 15.9 0.2 0.036 14.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) PXB PF12828.7 ORY53619.1 - 0.061 13.3 0.0 0.098 12.6 0.0 1.3 1 1 0 1 1 1 0 PX-associated IHO1 PF15771.5 ORY53619.1 - 0.19 10.5 0.2 0.45 9.2 0.1 1.6 2 0 0 2 2 2 0 Interactor of HORMAD1 protein 1 GTP_EFTU PF00009.27 ORY53620.1 - 2.3e-45 154.6 0.0 3.4e-45 154.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 ORY53620.1 - 3.1e-14 53.2 0.1 1.1e-13 51.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 ORY53620.1 - 2.3e-08 34.3 0.2 8.3e-08 32.5 0.2 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 ORY53620.1 - 7.6e-05 22.8 0.0 0.00038 20.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 ORY53620.1 - 0.025 14.4 0.7 0.25 11.3 0.2 2.5 2 0 0 2 2 2 0 Elongation factor Tu domain 4 AAA_22 PF13401.6 ORY53620.1 - 0.088 13.1 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 ORY53620.1 - 0.23 10.6 0.2 0.69 9.0 0.1 1.8 2 0 0 2 2 2 0 G-protein alpha subunit PBP1_TM PF14812.6 ORY53620.1 - 0.51 10.7 8.8 1 9.8 8.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ABC_tran PF00005.27 ORY53621.1 - 1.5e-39 135.6 0.1 2.9e-23 82.9 0.0 3.6 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 ORY53621.1 - 4.7e-08 33.2 0.0 0.076 12.8 0.0 3.4 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY53621.1 - 6.1e-08 32.4 0.2 0.007 15.8 0.0 3.4 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 ORY53621.1 - 0.0017 18.6 0.1 0.3 11.4 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 ORY53621.1 - 0.0075 16.4 0.0 0.023 14.8 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY53621.1 - 0.012 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase MeaB PF03308.16 ORY53621.1 - 0.019 14.0 1.8 0.043 12.8 0.1 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 ORY53621.1 - 0.085 12.6 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 ORY53621.1 - 0.37 11.2 4.0 0.33 11.4 0.4 2.3 2 1 0 2 2 2 0 AAA domain Cadherin-like PF12733.7 ORY53622.1 - 1.3e-13 51.3 1.3 9.9e-10 38.8 0.5 5.5 3 1 1 4 4 2 2 Cadherin-like beta sandwich domain LRR_8 PF13855.6 ORY53622.1 - 9.4e-12 44.5 1.0 0.00011 21.9 0.0 2.6 2 0 0 2 2 2 2 Leucine rich repeat TPR_11 PF13414.6 ORY53622.1 - 5.9e-10 38.7 5.5 0.00089 18.9 0.1 5.7 5 1 1 6 6 6 3 TPR repeat LRR_4 PF12799.7 ORY53622.1 - 6.7e-10 39.1 5.3 0.00017 21.9 1.0 2.8 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) TPR_2 PF07719.17 ORY53622.1 - 5.7e-08 32.3 0.8 0.00045 20.1 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 ORY53622.1 - 1.3e-07 32.0 0.0 3.2e-05 24.3 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 ORY53622.1 - 1.2e-05 25.4 0.3 0.021 15.2 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 ORY53622.1 - 1.2e-05 25.1 1.2 0.0022 18.1 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 ORY53622.1 - 6.1e-05 22.7 1.6 0.063 13.1 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat LRR_1 PF00560.33 ORY53622.1 - 0.00084 19.6 0.1 19 6.3 0.0 5.0 4 0 0 4 4 4 0 Leucine Rich Repeat ANAPC3 PF12895.7 ORY53622.1 - 0.00095 19.3 0.5 0.23 11.7 0.0 4.0 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 ORY53622.1 - 0.0036 17.5 0.4 0.018 15.3 0.0 2.4 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 ORY53622.1 - 0.0072 17.1 0.0 0.04 14.7 0.0 2.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 ORY53622.1 - 0.01 16.0 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat LRR_6 PF13516.6 ORY53622.1 - 0.011 15.8 3.2 11 6.4 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich repeat TPR_16 PF13432.6 ORY53622.1 - 0.015 15.9 0.0 0.11 13.1 0.0 2.6 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 ORY53622.1 - 0.086 12.9 0.0 0.84 9.8 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TFIIE_alpha PF02002.17 ORY53623.1 - 9e-14 51.2 5.6 1.9e-13 50.2 5.6 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit Zn-ribbon_8 PF09723.10 ORY53623.1 - 0.033 14.3 1.3 0.074 13.2 1.3 1.6 1 0 0 1 1 1 0 Zinc ribbon domain protein_MS5 PF04776.12 ORY53623.1 - 0.074 13.2 0.9 0.12 12.4 0.9 1.2 1 0 0 1 1 1 0 Protein MS5 TF_Zn_Ribbon PF08271.12 ORY53623.1 - 0.075 12.6 0.3 0.18 11.3 0.3 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding dsrm PF00035.26 ORY53624.1 - 0.003 18.2 0.1 0.0093 16.7 0.1 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif Glyco_transf_90 PF05686.12 ORY53626.1 - 3.1e-06 26.4 0.1 8.8e-06 24.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 90 TPMT PF05724.11 ORY53627.1 - 3.9e-25 88.8 0.0 6.1e-25 88.2 0.0 1.3 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.6 ORY53627.1 - 0.0015 18.3 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 ORY53627.1 - 0.038 14.7 0.0 0.058 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PITH PF06201.13 ORY53628.1 - 8.5e-38 130.0 1.2 1.2e-37 129.5 1.2 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 ORY53628.1 - 5e-27 93.9 0.0 9.4e-27 93.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 ORY53628.1 - 2.3e-05 24.6 0.0 6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 ORY53628.1 - 7.2e-05 23.2 0.3 0.00082 19.8 0.1 2.5 2 1 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 ORY53628.1 - 0.0015 17.9 0.0 0.0023 17.4 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 ORY53628.1 - 0.003 17.7 0.0 0.0072 16.5 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like AA_permease_N PF08403.10 ORY53628.1 - 0.013 15.0 0.0 0.032 13.7 0.0 1.7 1 0 0 1 1 1 0 Amino acid permease N-terminal Phosducin PF02114.16 ORY53628.1 - 0.026 13.5 0.0 0.11 11.4 0.0 1.9 2 0 0 2 2 2 0 Phosducin Thioredoxin_9 PF14595.6 ORY53628.1 - 0.043 13.6 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin AhpC-TSA PF00578.21 ORY53628.1 - 0.044 13.7 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.10 ORY53628.1 - 0.069 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Redoxin DUF2139 PF09910.9 ORY53628.1 - 0.15 11.2 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2139) zf-rbx1 PF12678.7 ORY53629.1 - 1.7e-21 76.2 10.4 2.2e-21 75.9 10.4 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 ORY53629.1 - 5.1e-14 52.1 7.8 6.4e-14 51.8 7.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 ORY53629.1 - 2e-05 24.8 12.3 0.00035 20.8 12.3 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 ORY53629.1 - 0.00014 21.7 6.0 0.00085 19.1 6.0 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 ORY53629.1 - 0.0025 17.6 5.8 0.011 15.6 0.8 2.2 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 ORY53629.1 - 0.0072 16.1 12.3 0.0094 15.8 6.7 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 ORY53629.1 - 1.5 9.0 6.6 0.51 10.5 0.3 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 ORY53629.1 - 3.7 7.7 7.3 24 5.1 7.3 2.2 1 1 0 1 1 1 0 RING-type zinc-finger FTHFS PF01268.19 ORY53630.1 - 7e-215 714.4 0.2 1.1e-211 703.9 0.0 3.7 2 1 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 ORY53630.1 - 1.5e-66 222.6 3.0 2.7e-66 221.8 3.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 ORY53630.1 - 1.5e-26 92.9 0.2 4.2e-12 46.4 0.0 2.5 1 1 1 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Zip PF02535.22 ORY53632.1 - 8e-38 130.5 12.6 1.9e-37 129.3 12.6 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter Glyco_hydro_18 PF00704.28 ORY53633.1 - 1.4e-12 48.0 0.0 1.7e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ODV-E18 PF10717.9 ORY53633.1 - 0.036 13.9 0.5 0.096 12.6 0.5 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 OppC_N PF12911.7 ORY53633.1 - 0.05 13.6 0.1 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C GRA6 PF05084.13 ORY53633.1 - 0.065 13.2 0.3 0.11 12.4 0.3 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) DUF515 PF04415.12 ORY53633.1 - 0.25 9.7 0.0 0.38 9.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF2749 PF10907.8 ORY53633.1 - 0.46 10.7 1.3 0.88 9.8 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2749) Glyco_hydro_18 PF00704.28 ORY53634.1 - 4.9e-11 42.9 0.0 5.5e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 OppC_N PF12911.7 ORY53634.1 - 0.1 12.6 0.1 0.25 11.3 0.1 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Gti1_Pac2 PF09729.9 ORY53636.1 - 7e-20 71.9 0.0 4.2e-15 56.3 0.0 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family SLBP_RNA_bind PF15247.6 ORY53636.1 - 0.038 14.1 0.4 0.07 13.3 0.4 1.4 1 0 0 1 1 1 0 Histone RNA hairpin-binding protein RNA-binding domain CD34_antigen PF06365.12 ORY53637.1 - 0.16 11.5 0.1 0.2 11.2 0.1 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family PH PF00169.29 ORY53639.1 - 2.3e-08 34.5 0.5 4.6e-08 33.5 0.5 1.5 1 0 0 1 1 1 1 PH domain RA PF00788.23 ORY53639.1 - 0.0018 18.9 0.0 0.0054 17.3 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PH_11 PF15413.6 ORY53639.1 - 0.1 13.0 0.4 0.29 11.6 0.4 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain DUF4203 PF13886.6 ORY53641.1 - 7.7e-37 126.9 36.2 1.2e-36 126.3 36.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) PHO4 PF01384.20 ORY53642.1 - 3e-112 375.0 23.9 4e-112 374.6 23.9 1.2 1 0 0 1 1 1 1 Phosphate transporter family Bacteriocin_IIi PF11758.8 ORY53642.1 - 0.01 15.7 0.3 0.028 14.2 0.3 1.8 1 0 0 1 1 1 0 Aureocin-like type II bacteriocin DUF1240 PF06836.12 ORY53642.1 - 0.34 11.5 2.0 0.36 11.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) DUF4017 PF13209.6 ORY53642.1 - 0.35 10.8 3.1 0.26 11.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4017) ATP_bind_1 PF03029.17 ORY53643.1 - 1.6e-80 270.4 0.4 1.8e-80 270.2 0.4 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein Zip PF02535.22 ORY53644.1 - 6.3e-50 170.3 8.3 8.1e-50 169.9 8.3 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Glu_synthase PF01645.17 ORY53645.1 - 2e-80 270.7 0.3 2.6e-80 270.3 0.3 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase FMN_dh PF01070.18 ORY53645.1 - 0.00091 18.3 0.4 0.0016 17.6 0.4 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Zip PF02535.22 ORY53646.1 - 2.3e-48 165.2 10.6 4.2e-48 164.3 10.6 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter DUF624 PF04854.14 ORY53646.1 - 4.6 7.4 10.3 3.2 7.9 0.2 3.3 3 1 0 3 3 3 0 Protein of unknown function, DUF624 Zip PF02535.22 ORY53648.1 - 4.7e-46 157.6 6.1 6.1e-46 157.2 6.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.22 ORY53649.1 - 2.2e-50 171.8 15.9 2.2e-50 171.8 15.9 1.8 2 0 0 2 2 2 1 ZIP Zinc transporter Mitovir_RNA_pol PF05919.11 ORY53649.1 - 0.059 12.5 0.0 0.084 12.0 0.0 1.1 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase YEATS PF03366.16 ORY53650.1 - 4.9e-32 109.7 0.2 9.2e-32 108.9 0.2 1.5 1 0 0 1 1 1 1 YEATS family FANCI_HD2 PF14680.6 ORY53650.1 - 0.029 13.6 0.3 0.039 13.2 0.3 1.1 1 0 0 1 1 1 0 FANCI helical domain 2 APG6_N PF17675.1 ORY53650.1 - 0.13 12.8 2.6 0.2 12.2 2.6 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region zf-CSL PF05207.13 ORY53651.1 - 4.1e-18 64.8 3.6 5.5e-18 64.5 3.6 1.2 1 0 0 1 1 1 1 CSL zinc finger zinc_ribbon_4 PF13717.6 ORY53651.1 - 0.019 14.9 1.6 0.044 13.7 1.6 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DnaJ PF00226.31 ORY53651.1 - 0.093 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 DnaJ domain Glyco_hydro_20 PF00728.22 ORY53652.1 - 5.4e-76 256.3 0.0 6.5e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY53652.1 - 1.1e-06 29.3 1.8 1.5e-06 28.9 0.5 1.9 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY53652.1 - 7.7e-05 23.5 0.0 0.00018 22.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Pkinase PF00069.25 ORY53653.1 - 1.5e-42 145.8 0.0 2.3e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY53653.1 - 3e-26 92.3 0.0 4.3e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY53653.1 - 0.00083 18.8 0.0 0.0017 17.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 ORY53653.1 - 0.004 17.1 0.0 0.58 10.0 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family PIP49_C PF12260.8 ORY53653.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Haspin_kinase PF12330.8 ORY53653.1 - 0.24 10.3 0.0 0.39 9.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Calcipressin PF04847.12 ORY53654.1 - 2.3e-27 95.9 0.1 1.2e-26 93.6 0.0 1.8 2 0 0 2 2 2 1 Calcipressin RRM_1 PF00076.22 ORY53654.1 - 0.097 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cor1 PF04803.12 ORY53655.1 - 0.0042 17.3 0.3 0.078 13.2 0.1 2.1 2 0 0 2 2 2 1 Cor1/Xlr/Xmr conserved region DUF1269 PF06897.12 ORY53655.1 - 0.066 13.5 1.6 1.5 9.2 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1269) GM_CSF PF01109.17 ORY53655.1 - 0.13 12.5 0.2 0.47 10.6 0.2 2.0 1 1 1 2 2 2 0 Granulocyte-macrophage colony-stimulating factor Myb_DNA-bind_3 PF12776.7 ORY53656.1 - 5.3e-09 36.9 0.0 1.2e-08 35.8 0.0 1.6 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 ORY53656.1 - 0.0087 16.4 0.2 0.022 15.1 0.0 1.7 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 ORY53656.1 - 0.033 14.3 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain V-set PF07686.17 ORY53656.1 - 0.057 13.6 0.2 11 6.2 0.0 2.9 3 0 0 3 3 3 0 Immunoglobulin V-set domain PI3K_1B_p101 PF10486.9 ORY53656.1 - 0.13 10.0 0.1 0.17 9.6 0.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Dynamin_N PF00350.23 ORY53657.1 - 9.6e-13 48.5 0.1 2e-11 44.2 0.0 3.1 3 2 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 ORY53657.1 - 0.00086 19.4 0.0 0.011 15.8 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 ORY53657.1 - 0.0021 18.0 0.5 0.0063 16.4 0.2 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 ORY53657.1 - 0.005 16.6 0.7 0.01 15.5 0.7 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 ORY53657.1 - 0.0071 16.7 2.2 0.02 15.3 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain IIGP PF05049.13 ORY53657.1 - 0.011 14.8 0.4 0.037 13.1 0.2 2.1 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) TMF_DNA_bd PF12329.8 ORY53657.1 - 0.011 15.7 2.8 0.011 15.7 2.8 4.6 5 0 0 5 5 5 0 TATA element modulatory factor 1 DNA binding ABC_tran PF00005.27 ORY53657.1 - 0.02 15.4 0.1 0.02 15.4 0.1 3.5 2 1 1 3 3 3 0 ABC transporter FtsK_SpoIIIE PF01580.18 ORY53657.1 - 0.04 13.3 1.6 0.35 10.2 0.3 2.6 2 1 0 2 2 2 0 FtsK/SpoIIIE family NOA36 PF06524.12 ORY53657.1 - 0.07 12.4 0.8 0.14 11.5 0.8 1.4 1 0 0 1 1 1 0 NOA36 protein DUF4795 PF16043.5 ORY53657.1 - 0.3 10.7 22.6 4 7.0 11.0 3.5 2 2 0 3 3 3 0 Domain of unknown function (DUF4795) Med30 PF11315.8 ORY53657.1 - 0.55 10.4 6.8 0.078 13.2 2.0 2.0 2 0 0 2 2 1 0 Mediator complex subunit 30 WXG100 PF06013.12 ORY53657.1 - 0.62 10.3 5.6 13 6.1 0.1 3.6 3 1 0 3 3 3 0 Proteins of 100 residues with WXG DUF87 PF01935.17 ORY53657.1 - 3.8 7.5 12.2 3.9 7.5 0.1 3.5 3 0 0 3 3 3 0 Helicase HerA, central domain DASH_Duo1 PF08651.10 ORY53657.1 - 7.6 6.4 7.7 7 6.5 0.2 3.4 2 1 1 3 3 3 0 DASH complex subunit Duo1 CENP-B_dimeris PF09026.10 ORY53658.1 - 1.6 9.1 8.2 1.9 8.9 2.0 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Glyco_hydro_20 PF00728.22 ORY53659.1 - 4.1e-76 256.7 0.0 5.2e-76 256.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 ORY53659.1 - 1.3e-13 51.7 0.6 1.9e-12 48.0 0.6 2.2 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 ORY53659.1 - 3.3e-11 44.0 0.1 1.4e-10 42.0 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Gti1_Pac2 PF09729.9 ORY53660.1 - 1.9e-10 41.1 0.0 1e-06 29.0 0.0 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family ArgJ PF01960.18 ORY53661.1 - 3.1e-113 378.3 3.3 3.4e-113 378.2 3.3 1.0 1 0 0 1 1 1 1 ArgJ family IBN_N PF03810.19 ORY53662.1 - 4.1e-13 49.0 0.0 3.5e-11 42.8 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 ORY53662.1 - 0.00013 20.9 0.1 0.0012 17.8 0.0 2.2 2 0 0 2 2 2 1 Cse1 MMS19_C PF12460.8 ORY53662.1 - 0.021 14.0 0.3 0.021 14.0 0.3 2.6 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal Xpo1 PF08389.12 ORY53662.1 - 0.046 13.8 0.0 0.046 13.8 0.0 2.9 4 0 0 4 4 4 0 Exportin 1-like protein Tetraspanin PF00335.20 ORY53663.1 - 0.09 12.5 13.8 0.086 12.5 5.0 2.2 2 0 0 2 2 2 0 Tetraspanin family SOR_SNZ PF01680.17 ORY53664.1 - 1.4e-111 371.3 6.1 1.9e-111 370.8 6.1 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 ORY53664.1 - 1.4e-08 34.4 5.5 1.5e-07 31.0 0.3 2.5 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 ORY53664.1 - 9.2e-06 25.0 0.3 0.042 13.0 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) TetR_C_27 PF17935.1 ORY53664.1 - 0.00017 21.6 0.0 0.00048 20.1 0.0 1.8 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain NanE PF04131.14 ORY53664.1 - 0.0075 15.5 1.4 0.053 12.7 0.0 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 ORY53664.1 - 0.015 14.8 0.8 1.1 8.7 0.1 2.7 2 1 0 3 3 3 0 Histidine biosynthesis protein IGPS PF00218.21 ORY53664.1 - 0.03 13.5 1.2 0.6 9.2 0.0 3.0 3 2 1 4 4 4 0 Indole-3-glycerol phosphate synthase Milton PF12448.8 ORY53664.1 - 0.15 12.1 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Kinesin associated protein NMO PF03060.15 ORY53664.1 - 0.51 9.7 7.6 0.59 9.5 0.9 2.4 2 1 0 2 2 2 0 Nitronate monooxygenase zf-C2H2 PF00096.26 ORY53666.1 - 2e-09 37.4 12.4 1.4e-05 25.2 2.5 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY53666.1 - 4.7e-07 29.9 15.2 1.4e-06 28.5 5.3 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY53666.1 - 2.8e-06 27.7 15.6 0.0024 18.6 1.8 3.0 2 1 1 3 3 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 ORY53666.1 - 0.00031 21.3 1.9 0.054 14.1 0.3 2.1 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_8 PF15909.5 ORY53666.1 - 0.00033 20.9 0.8 0.052 13.9 0.2 2.0 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 ORY53666.1 - 0.0074 16.4 2.3 1.4 9.1 0.2 2.0 1 1 1 2 2 2 2 Aberrant zinc-finger zf_C2H2_ZHX PF18387.1 ORY53666.1 - 0.083 12.5 4.8 0.37 10.5 2.8 2.1 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_6 PF13912.6 ORY53666.1 - 0.27 11.3 0.1 0.27 11.3 0.1 2.7 2 1 0 2 2 2 0 C2H2-type zinc finger Terminase_GpA PF05876.12 ORY53666.1 - 0.32 9.5 1.8 0.38 9.2 1.8 1.0 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) STE PF02200.16 ORY53667.1 - 1.5e-50 170.2 0.0 1.7e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 STE like transcription factor DUF2278 PF10042.9 ORY53667.1 - 0.041 13.9 0.0 0.05 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) TPR_1 PF00515.28 ORY53668.1 - 4.1e-23 80.2 6.1 1.6e-07 30.8 0.1 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 ORY53668.1 - 3.6e-20 70.4 7.2 2.4e-06 27.2 0.1 5.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 ORY53668.1 - 1.7e-18 66.0 2.5 7.6e-06 25.5 0.7 4.6 3 1 1 4 4 4 4 TPR repeat TPR_14 PF13428.6 ORY53668.1 - 1e-16 60.2 7.0 8.4e-05 23.1 0.4 5.9 3 2 4 7 7 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 ORY53668.1 - 7.2e-15 55.3 7.5 7.4e-09 36.0 1.2 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 ORY53668.1 - 1.2e-14 53.1 2.4 0.0024 17.9 0.0 5.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 ORY53668.1 - 1.4e-14 53.3 7.3 0.00082 19.6 0.1 5.2 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 ORY53668.1 - 1.8e-14 53.6 6.0 2.8e-08 33.8 0.9 3.6 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 ORY53668.1 - 5.6e-12 46.1 11.8 1.6e-07 31.8 3.4 4.0 3 2 2 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 ORY53668.1 - 4.8e-11 42.8 3.3 0.00083 19.6 2.0 4.8 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_20 PF14561.6 ORY53668.1 - 6.1e-10 39.3 3.3 0.00011 22.5 0.2 3.6 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 ORY53668.1 - 1.8e-08 33.8 2.0 1.3 9.2 0.2 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 ORY53668.1 - 4.3e-08 33.3 4.5 0.63 10.8 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 ORY53668.1 - 1.2e-07 31.8 6.1 2.7e-05 24.3 0.8 2.9 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 ORY53668.1 - 4.6e-06 26.6 3.1 0.0038 17.3 0.2 3.9 3 1 1 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 ORY53668.1 - 1.6e-05 24.6 9.2 0.0091 15.8 0.4 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.17 ORY53668.1 - 0.0025 18.2 2.7 0.088 13.2 0.1 3.2 1 1 2 3 3 3 1 Bacterial transcriptional activator domain DUF4248 PF14053.6 ORY53668.1 - 0.0089 16.0 1.7 0.57 10.3 0.1 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF4248) TPR_4 PF07721.14 ORY53668.1 - 0.018 15.6 1.6 0.11 13.1 0.5 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat Paf67 PF10255.9 ORY53668.1 - 0.024 13.7 0.1 0.037 13.0 0.1 1.2 1 0 0 1 1 1 0 RNA polymerase I-associated factor PAF67 TMEM237 PF15383.6 ORY53670.1 - 0.00012 21.3 0.0 0.036 13.1 0.0 2.3 2 0 0 2 2 2 2 Transmembrane protein 237 DUF1772 PF08592.11 ORY53670.1 - 0.0045 17.3 0.4 0.068 13.5 0.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF1772) TRAPP PF04051.16 ORY53671.1 - 1.4e-41 141.6 0.0 1.7e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF676 PF05057.14 ORY53672.1 - 9.7e-27 93.9 0.0 1.8e-26 93.0 0.0 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 ORY53672.1 - 1.6e-07 31.4 0.0 1.9e-07 31.2 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 ORY53672.1 - 2.8e-06 28.1 0.0 3.3e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 ORY53672.1 - 5.6e-06 26.3 0.1 8.4e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 ORY53672.1 - 0.00017 21.5 0.0 0.00024 21.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.11 ORY53672.1 - 0.027 13.8 0.0 5 6.4 0.0 2.9 1 1 2 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 ORY53672.1 - 0.047 13.0 0.3 0.22 10.8 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 UPF0227 PF05728.12 ORY53672.1 - 0.052 13.5 0.1 0.11 12.5 0.1 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Esterase PF00756.20 ORY53672.1 - 0.08 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative esterase LCAT PF02450.15 ORY53672.1 - 0.09 11.9 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.7 ORY53672.1 - 0.17 11.7 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1731 PF08338.11 ORY53672.1 - 0.19 11.6 0.4 0.57 10.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) NUC194 PF08163.12 ORY53674.1 - 1.6e-61 208.3 0.2 3.9e-61 207.1 0.2 1.6 1 0 0 1 1 1 1 NUC194 domain PI3_PI4_kinase PF00454.27 ORY53674.1 - 9.2e-47 159.9 0.4 2.8e-46 158.4 0.0 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 ORY53674.1 - 3.6e-15 56.0 0.1 1.1e-14 54.4 0.1 1.9 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 ORY53674.1 - 1.7e-09 37.3 0.3 4.5e-08 32.8 0.1 2.7 2 0 0 2 2 2 1 FATC domain MMS19_N PF14500.6 ORY53674.1 - 0.53 9.8 8.0 0.39 10.3 0.2 4.3 3 1 1 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II Hph PF13694.6 ORY53674.1 - 6.9 6.9 8.5 1.5 9.1 3.8 2.2 2 0 0 2 2 2 0 Sec63/Sec62 complex-interacting family Gar1 PF04410.14 ORY53675.1 - 1.1e-35 122.7 0.2 1.5e-35 122.3 0.2 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region RabGAP-TBC PF00566.18 ORY53676.1 - 3.8e-60 203.2 0.2 3.8e-60 203.2 0.2 2.0 2 1 0 2 2 2 1 Rab-GTPase-TBC domain bZIP_1 PF00170.21 ORY53676.1 - 0.0036 17.3 8.6 0.69 10.1 2.0 3.1 2 1 1 3 3 3 2 bZIP transcription factor DUF2122 PF09895.9 ORY53676.1 - 0.039 14.4 3.6 1.4 9.3 0.0 2.9 3 0 0 3 3 3 0 RecB-family nuclease (DUF2122) Tox-MPTase5 PF15641.6 ORY53676.1 - 0.093 12.8 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Metallopeptidase toxin 5 Syntaxin-6_N PF09177.11 ORY53676.1 - 0.28 11.8 9.4 4.6e+02 1.4 9.4 2.7 1 1 0 1 1 1 0 Syntaxin 6, N-terminal ADIP PF11559.8 ORY53676.1 - 0.42 10.7 17.5 0.53 10.4 3.2 2.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DivIC PF04977.15 ORY53676.1 - 0.51 10.1 11.8 0.091 12.5 2.2 2.7 1 1 0 2 2 2 0 Septum formation initiator Macoilin PF09726.9 ORY53676.1 - 1.2 7.7 12.5 1.6 7.2 12.5 1.1 1 0 0 1 1 1 0 Macoilin family Spc24 PF08286.11 ORY53676.1 - 1.5 9.1 11.2 0.89 9.8 0.9 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 ZapB PF06005.12 ORY53676.1 - 1.9 9.0 20.1 0.41 11.1 4.7 2.8 1 1 1 2 2 2 0 Cell division protein ZapB Fib_alpha PF08702.10 ORY53676.1 - 7.1 6.8 11.1 7.5 6.7 8.6 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Cellulase PF00150.18 ORY53677.1 - 0.00075 19.0 0.1 0.0069 15.8 0.1 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Peptidase_M24 PF00557.24 ORY53678.1 - 1.4e-52 178.4 0.2 1.8e-52 178.1 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 ORY53678.1 - 7.2e-08 32.6 7.1 1.8e-07 31.4 7.1 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding HMA PF00403.26 ORY53679.1 - 8.4e-12 45.4 0.1 9.9e-12 45.1 0.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 ORY53679.1 - 0.007 16.7 0.1 0.018 15.4 0.1 1.7 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain Methyltrn_RNA_3 PF02598.17 ORY53681.1 - 1e-82 277.9 0.0 1.2e-82 277.7 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase p450 PF00067.22 ORY53682.1 - 9.4e-63 212.5 0.0 1.1e-62 212.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ORY53683.1 - 1.7e-58 198.5 0.0 1.2e-56 192.5 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ORY53684.1 - 1.1e-57 195.9 0.0 7.8e-56 189.7 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_16 PF10294.9 ORY53685.1 - 1.1e-08 35.0 0.0 2e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 ORY53685.1 - 0.00013 21.5 0.0 0.00022 20.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_10 PF05971.12 ORY53685.1 - 0.031 13.6 0.0 0.069 12.5 0.0 1.5 1 1 1 2 2 2 0 RNA methyltransferase Fanconi_C PF02106.15 ORY53685.1 - 0.085 11.6 0.2 0.64 8.7 0.0 1.9 2 0 0 2 2 2 0 Fanconi anaemia group C protein BLOC1_2 PF10046.9 ORY53687.1 - 1.1e-14 54.5 0.6 1.4e-14 54.1 0.6 1.1 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 HD_2 PF12917.7 ORY53687.1 - 0.027 14.3 0.6 0.035 13.9 0.6 1.1 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme Not3 PF04065.15 ORY53687.1 - 0.1 12.0 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component AAA_13 PF13166.6 ORY53687.1 - 0.12 11.0 0.1 0.15 10.7 0.1 1.0 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.16 ORY53688.1 - 5.5e-13 48.6 24.9 5.5e-13 48.6 24.9 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 ORY53689.1 - 2.9e-56 191.1 0.0 4.1e-56 190.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 ORY53690.1 - 3.8e-54 184.2 0.0 5e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pro_isomerase PF00160.21 ORY53691.1 - 1.1e-50 172.0 0.5 2e-50 171.1 0.5 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 ORY53691.1 - 0.0015 18.6 0.0 0.0059 16.7 0.0 2.0 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 ORY53691.1 - 0.002 18.3 0.1 0.045 13.9 0.0 2.6 2 0 0 2 2 2 1 U-box domain Complex1_49kDa PF00346.19 ORY53692.1 - 1e-119 398.6 0.0 1.3e-119 398.3 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 ORY53692.1 - 0.00059 18.8 0.0 0.0013 17.8 0.0 1.5 1 1 0 1 1 1 1 Nickel-dependent hydrogenase Mucin PF01456.17 ORY53693.1 - 0.24 11.4 42.7 0.3 11.1 42.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein STAS PF01740.21 ORY53694.1 - 7.7e-05 22.3 0.1 0.00013 21.5 0.1 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 ORY53694.1 - 0.17 12.3 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 STAS domain HIT PF01230.23 ORY53695.1 - 5.1e-25 88.1 0.1 1e-24 87.1 0.0 1.4 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 ORY53695.1 - 3.1e-07 30.9 0.0 5.1e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Pro_isomerase PF00160.21 ORY53696.1 - 1.8e-25 90.0 0.0 2.4e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HET PF06985.11 ORY53698.1 - 1.5e-17 64.3 0.0 2.6e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FH2 PF02181.23 ORY53698.1 - 0.08 12.0 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain AAA PF00004.29 ORY53699.1 - 2.1e-18 67.0 0.0 5.4e-18 65.7 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 ORY53699.1 - 7.5e-11 42.3 0.2 1.3e-10 41.5 0.2 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA_16 PF13191.6 ORY53699.1 - 0.00097 19.6 0.0 0.0026 18.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 ORY53699.1 - 0.011 15.9 0.1 0.039 14.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 ORY53699.1 - 0.015 14.5 0.0 0.045 12.9 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 ORY53699.1 - 0.083 12.6 0.5 0.83 9.3 0.3 2.2 1 1 1 2 2 2 0 AAA domain RuvB_N PF05496.12 ORY53699.1 - 0.094 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 ORY53699.1 - 0.13 11.8 0.0 0.37 10.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 ORY53699.1 - 0.15 12.1 0.0 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 ORY53699.1 - 0.18 11.3 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 ORY53699.1 - 0.18 12.3 0.0 0.5 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain BC10 PF06726.12 ORY53700.1 - 8.6e-07 29.1 5.6 1.4e-06 28.4 5.6 1.3 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 SAC3_GANP PF03399.16 ORY53701.1 - 0.00011 21.7 0.2 0.00016 21.2 0.2 1.2 1 0 0 1 1 1 1 SAC3/GANP family EDR1 PF14381.6 ORY53701.1 - 0.067 12.9 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 DnaJ_C PF01556.18 ORY53702.1 - 4.4e-40 137.2 0.8 6.1e-40 136.7 0.8 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 ORY53702.1 - 6.1e-28 96.7 2.5 1.3e-27 95.7 2.5 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 ORY53702.1 - 2e-14 53.7 17.7 3.5e-14 52.9 17.7 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 ORY53702.1 - 0.00071 19.6 7.9 0.1 12.6 0.4 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 ORY53702.1 - 0.0014 18.5 10.9 0.28 11.2 1.0 3.3 3 0 0 3 3 3 2 Tryptophan RNA-binding attenuator protein inhibitory protein Gp-FAR-1 PF05823.12 ORY53702.1 - 0.025 14.9 0.1 0.058 13.8 0.1 1.5 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) TackOD1 PF18551.1 ORY53702.1 - 2.7 7.6 8.7 6.9 6.3 0.9 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 ORY53702.1 - 3 8.0 8.4 6.9 6.8 8.4 1.6 1 1 0 1 1 1 0 Double zinc ribbon Cytochrom_c3_2 PF14537.6 ORY53702.1 - 3 8.4 10.8 4.3 7.9 9.1 2.0 1 1 1 2 2 2 0 Cytochrome c3 zf-RING_10 PF16685.5 ORY53702.1 - 8.7 6.6 9.9 7.2 6.8 5.8 2.2 1 1 1 2 2 2 0 zinc RING finger of MSL2 Glyoxalase_4 PF13669.6 ORY53703.1 - 2.7e-21 75.9 0.0 3.4e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 ORY53703.1 - 5e-13 49.4 0.0 6.1e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 ORY53703.1 - 8.7e-05 22.7 0.0 0.00011 22.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 ORY53703.1 - 0.00043 21.1 0.0 0.00072 20.3 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain zf-C2H2 PF00096.26 ORY53704.1 - 0.00029 21.1 3.6 0.068 13.6 0.2 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY53704.1 - 0.0019 18.9 2.9 1.6 9.8 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.12 ORY53704.1 - 0.02 15.2 1.4 1.7 9.0 0.2 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 ORY53704.1 - 0.052 13.9 2.6 0.13 12.5 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.15 ORY53704.1 - 0.19 11.7 2.1 6.4 6.8 0.1 2.3 1 1 1 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2HE PF16278.5 ORY53704.1 - 4.5 7.8 5.7 9.8 6.7 1.4 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger DUF4470 PF14737.6 ORY53705.1 - 0.016 15.4 0.2 0.17 12.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4470) IQ PF00612.27 ORY53705.1 - 5.3 7.1 10.3 5.5 7.1 2.3 3.3 3 0 0 3 3 3 0 IQ calmodulin-binding motif SIR2 PF02146.17 ORY53706.1 - 3.4e-48 163.9 0.0 2e-47 161.4 0.0 2.1 1 1 0 1 1 1 1 Sir2 family zf-UBP PF02148.19 ORY53706.1 - 1.7e-13 50.7 4.6 1.7e-13 50.7 4.6 1.6 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein E6 PF00518.17 ORY53706.1 - 0.061 13.8 2.5 0.067 13.6 1.1 1.7 2 0 0 2 2 2 0 Early Protein (E6) NapB PF03892.14 ORY53706.1 - 0.3 11.1 1.6 0.54 10.3 1.6 1.3 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) Herpes_UL52 PF03121.15 ORY53707.1 - 5.8e-10 39.0 1.4 1.3e-09 37.8 1.4 1.6 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase PigN PF04987.14 ORY53708.1 - 1e-108 364.2 32.6 1.5e-108 363.6 32.6 1.3 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 ORY53708.1 - 2e-08 34.3 0.8 1.9e-07 31.0 0.3 2.0 1 1 1 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ORY53708.1 - 3e-06 26.8 0.1 6.3e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Sulfatase AAA_11 PF13086.6 ORY53709.1 - 2e-19 70.4 1.1 4.5e-10 39.8 0.0 2.0 1 1 1 2 2 2 2 AAA domain Helicase_RecD PF05127.14 ORY53709.1 - 1e-06 28.7 0.0 2.7e-06 27.3 0.0 1.8 1 1 0 1 1 1 1 Helicase AAA_19 PF13245.6 ORY53709.1 - 1.7e-06 28.4 0.1 3.5e-06 27.4 0.1 1.5 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 ORY53709.1 - 7.7e-05 22.8 0.1 0.00017 21.7 0.1 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 ORY53709.1 - 0.00064 19.5 0.0 0.002 17.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY53709.1 - 0.015 15.5 0.1 0.081 13.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 ORY53709.1 - 0.017 14.7 0.1 0.029 13.9 0.1 1.4 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Terminase_1 PF03354.15 ORY53709.1 - 0.15 10.6 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Phage Terminase RNA_Me_trans PF04252.13 ORY53711.1 - 1.5e-11 44.3 0.2 1.1e-10 41.4 0.2 1.9 1 1 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase F5_F8_type_C PF00754.25 ORY53712.1 - 0.0035 17.4 0.1 0.0071 16.5 0.1 1.6 1 1 0 1 1 1 1 F5/8 type C domain XRCC1_N PF01834.16 ORY53712.1 - 0.0064 16.5 0.0 0.0098 15.9 0.0 1.4 1 0 0 1 1 1 1 XRCC1 N terminal domain Myc_N PF01056.18 ORY53712.1 - 0.017 15.1 1.4 0.019 14.9 1.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region SLAIN PF15301.6 ORY53712.1 - 1.1 8.4 4.7 1.7 7.8 2.9 1.8 2 0 0 2 2 2 0 SLAIN motif-containing family Fcf1 PF04900.12 ORY53713.1 - 2.7e-34 117.5 1.7 2.7e-34 117.5 1.7 1.7 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 ORY53713.1 - 2.7e-09 37.3 0.3 1.1e-08 35.4 0.0 1.8 2 0 0 2 2 2 1 PIN like domain DUF116 PF01976.17 ORY53713.1 - 0.025 14.1 1.8 0.047 13.2 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF116 DUF5024 PF16427.5 ORY53713.1 - 0.082 13.2 0.6 0.62 10.4 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5024) DHHC PF01529.20 ORY53714.1 - 7.8e-33 113.4 15.7 7.8e-33 113.4 15.7 2.2 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF996 PF06195.13 ORY53714.1 - 0.084 13.2 0.5 0.084 13.2 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF996) DUF898 PF05987.13 ORY53714.1 - 2.7 6.9 6.0 0.15 11.1 0.4 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) DUF962 PF06127.11 ORY53715.1 - 5.4e-26 90.5 0.1 1.1e-25 89.5 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF3759 PF12585.8 ORY53717.1 - 1.3e-18 66.8 5.0 2.8e-18 65.7 5.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF962 PF06127.11 ORY53717.1 - 1.1e-09 38.2 0.6 7.4e-09 35.6 0.6 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Methyltransf_21 PF05050.12 ORY53719.1 - 5.8e-07 29.7 0.3 1.3e-06 28.6 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase FkbM domain PNGaseA PF12222.8 ORY53722.1 - 1.2e-67 228.7 3.1 1.7e-67 228.2 3.1 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A WD40 PF00400.32 ORY53723.1 - 0.0087 16.9 0.0 12 7.0 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY53723.1 - 0.015 15.6 0.0 0.086 13.2 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 ORY53723.1 - 0.075 13.0 0.0 0.67 10.0 0.0 2.5 3 0 0 3 3 3 0 PQQ enzyme repeat Mpp10 PF04006.12 ORY53723.1 - 1.7 7.0 20.0 3.5 5.9 0.4 2.1 2 0 0 2 2 2 0 Mpp10 protein CDC45 PF02724.14 ORY53723.1 - 4.8 5.4 8.9 0.16 10.3 2.7 1.6 2 0 0 2 2 2 0 CDC45-like protein SH3_9 PF14604.6 ORY53724.1 - 1.6e-08 34.2 0.4 2e-08 34.0 0.0 1.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 ORY53724.1 - 8.7e-08 31.7 0.0 1.4e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 ORY53724.1 - 4.8e-05 23.0 0.0 6.5e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 ORY53726.1 - 2.8e-08 33.2 0.0 4.3e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 ORY53726.1 - 2.4e-05 24.1 0.0 4.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Mid2 PF04478.12 ORY53726.1 - 0.0011 18.8 0.4 0.0023 17.8 0.4 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SH3_2 PF07653.17 ORY53726.1 - 0.0013 18.4 0.0 0.0022 17.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Shisa PF13908.6 ORY53726.1 - 0.0013 19.0 1.7 0.0029 17.9 1.7 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Orthoreo_P10 PF07204.11 ORY53726.1 - 0.0084 16.0 1.1 0.021 14.7 0.0 2.1 2 0 0 2 2 2 1 Orthoreovirus membrane fusion protein p10 Adeno_E3_CR2 PF02439.15 ORY53726.1 - 0.065 13.0 5.0 0.14 11.9 5.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SH3_1 PF00018.28 ORY53727.1 - 1.1e-10 40.9 0.0 3.8e-06 26.4 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 ORY53727.1 - 3.3e-10 39.6 0.0 4.2e-05 23.3 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain DUF131 PF01998.17 ORY53727.1 - 0.024 14.3 0.4 0.056 13.1 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF131 SH3_2 PF07653.17 ORY53727.1 - 0.048 13.3 0.0 8.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Variant SH3 domain DDDD PF10161.9 ORY53727.1 - 0.1 12.4 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Putative mitochondrial precursor protein SH3_9 PF14604.6 ORY53728.1 - 1.4e-34 117.7 5.7 2.8e-12 46.3 0.2 3.2 3 0 0 3 3 3 3 Variant SH3 domain SH3_1 PF00018.28 ORY53728.1 - 1.7e-29 101.2 1.4 1.9e-08 33.8 0.0 3.3 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.17 ORY53728.1 - 9e-13 47.7 0.1 0.00094 18.8 0.0 3.3 3 0 0 3 3 3 3 Variant SH3 domain DAP10 PF07213.11 ORY53728.1 - 0.0075 16.2 0.3 0.0075 16.2 0.3 2.2 2 0 0 2 2 2 1 DAP10 membrane protein TMEM154 PF15102.6 ORY53728.1 - 0.012 15.5 0.3 0.032 14.2 0.1 1.7 2 0 0 2 2 2 0 TMEM154 protein family Orthoreo_P10 PF07204.11 ORY53728.1 - 0.018 15.0 1.8 0.036 14.0 0.0 2.3 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 DUF3948 PF13134.6 ORY53728.1 - 0.32 10.7 1.4 1.5 8.6 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) Epimerase PF01370.21 ORY53729.1 - 6.5e-09 35.6 0.8 7.4e-06 25.6 0.0 2.3 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 ORY53729.1 - 0.011 14.9 0.1 0.034 13.3 0.1 1.7 1 1 1 2 2 2 0 Male sterility protein 3Beta_HSD PF01073.19 ORY53729.1 - 0.015 14.3 0.0 1.3 8.0 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 ORY53729.1 - 0.087 11.9 0.2 0.47 9.5 0.0 2.1 2 1 1 3 3 3 0 RmlD substrate binding domain Homeodomain PF00046.29 ORY53731.1 - 1.8e-11 43.7 1.6 3e-11 43.0 1.6 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 ORY53731.1 - 5.8e-07 29.3 0.2 1.1e-06 28.4 0.2 1.5 1 0 0 1 1 1 1 Homeobox KN domain Peptidase_C48 PF02902.19 ORY53732.1 - 0.085 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain THOC7 PF05615.13 ORY53733.1 - 2.3e-08 34.4 5.0 2.3e-08 34.4 5.0 1.7 1 1 0 1 1 1 1 Tho complex subunit 7 PEARLI-4 PF05278.12 ORY53733.1 - 0.0018 18.0 1.6 0.0025 17.5 1.6 1.2 1 0 0 1 1 1 1 Arabidopsis phospholipase-like protein (PEARLI 4) DUF848 PF05852.11 ORY53733.1 - 0.0037 17.4 3.2 0.0052 16.9 3.2 1.3 1 0 0 1 1 1 1 Gammaherpesvirus protein of unknown function (DUF848) DNA_topoisoIV PF00521.20 ORY53733.1 - 0.14 11.1 3.8 0.16 10.8 3.8 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A FlaC_arch PF05377.11 ORY53733.1 - 0.19 12.1 3.6 3.9 7.9 0.6 2.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF2730 PF10805.8 ORY53733.1 - 0.35 11.0 4.1 9.2 6.4 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Fungal_TACC PF12709.7 ORY53733.1 - 0.79 10.2 5.1 4.3 7.9 1.5 2.3 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DUF4349 PF14257.6 ORY53733.1 - 1.3 8.4 10.0 3.8 6.9 2.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) ABC_tran_CTD PF16326.5 ORY53733.1 - 2.8 8.2 11.7 1.9 8.8 2.5 2.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain DivIC PF04977.15 ORY53733.1 - 3.3 7.6 8.9 7.7 6.4 1.4 2.5 1 1 0 2 2 2 0 Septum formation initiator DUF4639 PF15479.6 ORY53734.1 - 6.1e-18 65.1 0.6 7.8e-17 61.4 0.1 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4639) SET PF00856.28 ORY53735.1 - 4.1e-11 43.5 0.0 6.1e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 SET domain His_Phos_2 PF00328.22 ORY53736.1 - 1.2e-06 28.2 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) zf-C2H2 PF00096.26 ORY53738.1 - 7.6e-06 26.1 9.7 0.00018 21.8 1.0 3.5 2 1 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY53738.1 - 0.018 15.4 4.1 0.11 12.9 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double domain FOXP-CC PF16159.5 ORY53738.1 - 0.15 12.7 0.3 0.15 12.7 0.3 1.9 2 1 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 ORY53738.1 - 0.48 11.4 9.5 1.7 9.7 1.0 3.4 2 1 0 2 2 2 0 C2H2-type zinc finger WD40 PF00400.32 ORY53739.1 - 2.7e-05 24.8 1.6 0.88 10.6 0.0 4.8 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 ORY53739.1 - 3.4e-05 24.0 0.0 2.6 8.4 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 ORY53739.1 - 0.0084 16.0 0.4 0.02 14.7 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF2415 PF10313.9 ORY53739.1 - 0.071 13.0 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Cytochrom_D1 PF02239.16 ORY53739.1 - 0.096 11.2 0.0 3.4 6.1 0.0 2.1 1 1 1 2 2 2 0 Cytochrome D1 heme domain Torus PF16131.5 ORY53740.1 - 2.6e-33 115.0 0.5 5.2e-33 114.0 0.5 1.5 1 0 0 1 1 1 1 Torus domain RRM_1 PF00076.22 ORY53740.1 - 4e-08 33.0 0.0 8.2e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 ORY53740.1 - 0.00099 19.1 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif PikAIV_N PF18605.1 ORY53740.1 - 0.0083 15.7 0.4 0.018 14.6 0.4 1.5 1 0 0 1 1 1 1 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain TMEM213 PF15192.6 ORY53740.1 - 0.47 10.5 2.3 1.4 8.9 2.1 1.9 2 0 0 2 2 2 0 TMEM213 family zf-CCHC_2 PF13696.6 ORY53741.1 - 0.00049 19.9 4.2 0.00078 19.2 4.2 1.3 1 0 0 1 1 1 1 Zinc knuckle SUIM_assoc PF16619.5 ORY53741.1 - 0.027 14.5 8.9 2.8 8.1 0.0 3.9 3 1 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 FTCD_C PF04961.12 ORY53741.1 - 0.063 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase HNF_C PF09354.10 ORY53741.1 - 0.071 14.2 6.9 0.44 11.6 2.2 3.3 2 1 0 2 2 2 0 HNF3 C-terminal domain ParA PF10609.9 ORY53742.1 - 1.2e-83 280.3 0.1 1.5e-83 280.1 0.1 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 ORY53742.1 - 2.3e-07 30.9 0.6 1.1e-05 25.5 0.8 2.6 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 ORY53742.1 - 7e-05 22.2 6.8 0.0011 18.3 2.9 2.8 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 ORY53742.1 - 7.6e-05 22.7 1.2 0.0053 16.7 0.8 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 ORY53742.1 - 0.0037 16.9 0.1 0.006 16.2 0.1 1.3 1 0 0 1 1 1 1 AAA domain MipZ PF09140.11 ORY53742.1 - 0.0041 16.4 0.2 0.015 14.6 0.2 1.8 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.6 ORY53742.1 - 0.013 15.3 2.1 0.17 11.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 ORY53742.1 - 0.12 11.8 0.5 0.3 10.5 0.5 1.6 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NB-ARC PF00931.22 ORY53742.1 - 0.2 10.8 0.0 0.36 10.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.17 ORY53742.1 - 0.31 10.7 0.4 12 5.6 0.3 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 ORY53742.1 - 0.31 10.9 1.6 0.58 10.0 0.5 1.8 2 0 0 2 2 2 0 RsgA GTPase zf-C4_ClpX PF06689.13 ORY53742.1 - 0.35 10.8 1.5 0.7 9.8 1.5 1.4 1 0 0 1 1 1 0 ClpX C4-type zinc finger zf-C2H2 PF00096.26 ORY53743.1 - 1.4e-11 44.2 30.2 4.6e-05 23.6 0.5 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY53743.1 - 1.7e-09 37.7 18.3 1.4e-05 25.3 0.4 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 ORY53743.1 - 1.3e-05 25.7 31.1 0.029 15.2 1.2 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY53743.1 - 0.00018 21.7 10.3 0.91 9.9 0.0 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 ORY53743.1 - 0.00072 19.9 13.9 0.18 12.3 0.0 4.5 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 ORY53743.1 - 0.013 16.1 5.6 0.013 16.1 5.6 2.1 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_6 PF13912.6 ORY53743.1 - 0.056 13.5 0.8 0.056 13.5 0.8 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORY53743.1 - 0.096 12.5 13.1 0.13 12.0 1.5 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type FOXP-CC PF16159.5 ORY53743.1 - 2.7 8.7 10.3 0.53 10.9 0.6 3.3 2 2 1 3 3 3 0 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 ORY53744.1 - 6.6e-08 32.6 2.8 0.0035 17.7 0.4 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 ORY53744.1 - 1e-07 32.0 14.1 0.00092 19.5 1.3 3.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY53744.1 - 1.1e-07 32.0 11.4 0.00082 20.0 1.5 3.0 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY53744.1 - 7.3e-05 22.9 0.0 0.46 10.8 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 ORY53744.1 - 0.00017 21.4 1.1 0.00039 20.2 1.1 1.6 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2_3rep PF18868.1 ORY53744.1 - 0.0016 19.1 2.7 0.036 14.7 0.7 2.6 2 1 0 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-met PF12874.7 ORY53744.1 - 0.006 16.9 2.2 8.2 7.0 0.1 3.7 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 ORY53744.1 - 0.0098 15.6 5.4 0.27 11.0 0.5 2.4 2 0 0 2 2 2 2 zinc-finger C2H2-type C5HCH PF17982.1 ORY53744.1 - 0.31 11.2 2.1 0.42 10.8 0.5 2.0 2 0 0 2 2 2 0 NSD Cys-His rich domain zf_C2H2_ZHX PF18387.1 ORY53744.1 - 0.96 9.1 4.4 3.3 7.4 0.5 2.7 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_6 PF13912.6 ORY53744.1 - 6.1 7.0 9.8 0.66 10.1 0.2 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY53745.1 - 6.6e-11 42.0 25.3 0.00014 22.2 2.1 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY53745.1 - 3.7e-07 30.4 24.0 0.0039 17.9 1.5 4.1 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_8 PF15909.5 ORY53745.1 - 0.00015 22.0 12.7 0.0017 18.6 4.6 2.6 1 1 1 2 2 2 2 C2H2-type zinc ribbon zf-H2C2_2 PF13465.6 ORY53745.1 - 0.00045 20.5 24.2 0.0032 17.8 0.2 4.5 5 0 0 5 5 4 2 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 ORY53745.1 - 0.0032 17.1 1.7 0.12 12.0 0.2 2.7 1 1 1 2 2 2 1 Zinc-fingers and homeoboxes C2H2 finger domain zf-met PF12874.7 ORY53745.1 - 0.0075 16.6 10.7 0.22 12.0 0.1 4.2 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 ORY53745.1 - 0.15 12.0 3.8 0.47 10.4 1.6 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Spt46 PF17734.1 ORY53745.1 - 0.26 11.0 7.7 1.8 8.3 7.7 2.6 1 1 0 1 1 1 0 Spermatogenesis-associated protein 46 zf-C2H2_jaz PF12171.8 ORY53745.1 - 0.7 10.2 10.1 0.85 10.0 0.1 3.6 4 0 0 4 4 3 0 Zinc-finger double-stranded RNA-binding zf-LYAR PF08790.11 ORY53745.1 - 0.73 9.8 5.5 12 5.9 0.4 3.0 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.5 ORY53745.1 - 0.88 9.4 15.8 0.1 12.3 1.2 3.3 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 ORY53745.1 - 1.6 9.4 11.6 5.9 7.6 1.3 3.2 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-MYST PF17772.1 ORY53745.1 - 4.9 6.8 8.6 0.47 10.1 0.2 2.7 3 0 0 3 3 3 0 MYST family zinc finger domain ABC2_membrane PF01061.24 ORY53746.1 - 1.1e-28 100.1 26.5 1.5e-28 99.7 26.5 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 ORY53746.1 - 1.9e-13 51.1 0.0 3.6e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 ORY53746.1 - 0.0043 16.9 0.0 0.0072 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 ORY53746.1 - 0.0069 15.8 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain MCM PF00493.23 ORY53746.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 MCM P-loop domain AAA_13 PF13166.6 ORY53746.1 - 0.098 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain SUIM_assoc PF16619.5 ORY53748.1 - 0.066 13.3 3.7 0.2 11.7 0.1 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Kazal_1 PF00050.21 ORY53748.1 - 0.1 12.6 0.6 0.23 11.5 0.6 1.5 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain zf-C2H2_4 PF13894.6 ORY53749.1 - 2.5e-11 43.4 17.9 0.00036 21.1 2.8 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY53749.1 - 5.1e-11 42.4 18.5 0.0017 18.7 3.6 3.4 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 ORY53749.1 - 6.7e-11 42.1 15.2 5.5e-05 23.4 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_11 PF16622.5 ORY53749.1 - 0.00092 18.9 12.8 0.0053 16.5 2.4 3.2 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 ORY53749.1 - 0.0018 18.5 7.1 0.017 15.4 1.9 2.2 1 1 1 2 2 2 2 C2H2-type zinc ribbon TraP PF07296.11 ORY53749.1 - 0.022 14.0 0.1 0.028 13.6 0.1 1.1 1 0 0 1 1 1 0 TraP protein zf-4CXXC_R1 PF10497.9 ORY53749.1 - 0.046 14.0 3.7 0.11 12.7 3.8 1.6 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-C2H2_3rep PF18868.1 ORY53749.1 - 0.047 14.4 3.4 1 10.0 0.7 2.3 1 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Baculo_ODV-E27 PF05314.11 ORY53749.1 - 0.17 11.1 0.0 0.22 10.6 0.0 1.1 1 0 0 1 1 1 0 Baculovirus occlusion-derived virus envelope protein EC27 zf-TRAF PF02176.18 ORY53749.1 - 0.27 12.0 9.9 2.3 9.0 0.5 2.8 2 1 0 2 2 2 0 TRAF-type zinc finger zf-C2H2_2 PF12756.7 ORY53749.1 - 0.45 10.9 9.3 3.7 7.9 1.6 2.7 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_aberr PF17017.5 ORY53749.1 - 0.89 9.7 0.1 0.89 9.7 0.1 2.1 2 0 0 2 2 2 0 Aberrant zinc-finger FOXP-CC PF16159.5 ORY53749.1 - 4.5 8.0 7.2 28 5.4 1.0 3.0 1 1 2 3 3 3 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 ORY53750.1 - 5.6e-12 45.4 10.4 0.0039 17.6 0.5 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY53750.1 - 1.4e-09 38.0 12.5 0.00099 19.8 0.4 3.9 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 ORY53750.1 - 0.00014 22.5 1.4 0.19 12.4 0.1 2.4 1 1 1 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 ORY53750.1 - 0.00033 20.9 13.0 0.013 15.9 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 ORY53750.1 - 0.0006 20.0 1.2 0.27 11.6 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 ORY53750.1 - 0.0019 18.4 4.7 0.009 16.3 1.5 2.3 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 ORY53750.1 - 0.0026 18.4 1.7 0.018 15.6 1.0 2.2 1 1 1 2 2 2 1 FOXP coiled-coil domain zf-C2H2_2 PF12756.7 ORY53750.1 - 0.007 16.7 2.2 0.19 12.0 2.2 2.8 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 ORY53750.1 - 0.032 14.6 1.2 28 5.3 0.0 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 ORY53750.1 - 0.21 11.4 0.2 0.21 11.4 0.2 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 ORY53750.1 - 0.22 11.3 0.3 0.22 11.3 0.3 4.0 5 0 0 5 5 5 0 C2H2-type zinc-finger domain C5HCH PF17982.1 ORY53750.1 - 1.8 8.8 6.7 0.89 9.8 2.3 2.5 1 1 1 2 2 2 0 NSD Cys-His rich domain zf-LYAR PF08790.11 ORY53750.1 - 7.8 6.5 9.0 2 8.4 0.1 3.2 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-C2H2 PF00096.26 ORY53751.1 - 1.3e-14 53.7 55.4 0.00055 20.2 0.5 7.1 6 1 1 7 7 7 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY53751.1 - 2e-13 49.9 50.9 0.0016 19.1 0.6 7.0 6 1 1 7 7 7 6 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 ORY53751.1 - 0.00011 22.4 33.7 0.57 10.5 0.7 6.3 6 0 0 6 6 6 4 Zinc-finger double-stranded RNA-binding FYVE PF01363.21 ORY53751.1 - 0.0029 17.7 8.0 0.0029 17.7 8.0 3.8 1 1 2 3 3 3 1 FYVE zinc finger zf-H2C2_2 PF13465.6 ORY53751.1 - 0.0063 16.9 55.4 0.019 15.4 4.6 8.1 6 2 1 7 7 7 3 Zinc-finger double domain zf-Di19 PF05605.12 ORY53751.1 - 0.038 14.3 4.0 0.038 14.3 4.0 3.9 2 1 2 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 ORY53751.1 - 0.16 11.8 0.1 0.16 11.8 0.1 5.6 6 2 0 6 6 6 0 C2H2-type zinc-finger domain zf-met PF12874.7 ORY53751.1 - 0.18 12.3 23.7 1.2 9.7 0.0 6.3 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY53751.1 - 0.63 10.1 24.4 2.6 8.1 0.2 5.5 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_2 PF12756.7 ORY53751.1 - 2.7 8.4 28.5 1.2 9.6 0.2 4.4 1 1 3 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 ORY53751.1 - 8.2 6.5 26.1 0.19 11.8 0.7 4.9 3 2 2 5 5 5 0 BED zinc finger zf-C2H2 PF00096.26 ORY53752.1 - 1.2e-15 57.0 10.5 5.7e-05 23.3 0.1 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY53752.1 - 1.9e-10 40.7 12.6 0.0017 19.1 0.7 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2HC_2 PF13913.6 ORY53752.1 - 2.5e-06 27.2 2.6 2.8e-05 23.9 2.2 2.4 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-met PF12874.7 ORY53752.1 - 0.0015 18.8 1.1 2.7 8.5 0.0 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-LYAR PF08790.11 ORY53752.1 - 0.0026 17.6 1.8 3.3 7.7 0.0 3.4 3 0 0 3 3 3 1 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.8 ORY53752.1 - 0.016 15.5 3.1 6.3 7.2 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 ORY53752.1 - 0.029 14.7 2.4 0.072 13.4 0.7 2.2 1 1 1 2 2 2 0 C2H2-type zinc ribbon zf-C2H2_11 PF16622.5 ORY53752.1 - 0.041 13.6 5.2 0.088 12.6 0.5 2.7 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-Di19 PF05605.12 ORY53752.1 - 0.091 13.1 2.0 5.4 7.4 0.3 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 ORY53752.1 - 0.37 11.3 7.5 3.7 8.2 0.2 3.8 4 0 0 4 4 4 0 Zinc-finger double domain zf-BED PF02892.15 ORY53752.1 - 1.8 8.6 4.0 6 7.0 0.0 2.6 3 0 0 3 3 3 0 BED zinc finger zf-C2H2_6 PF13912.6 ORY53752.1 - 8.1 6.6 8.3 20 5.3 0.1 3.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY53753.1 - 8.8e-05 22.7 16.0 0.009 16.4 2.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY53753.1 - 0.00033 21.2 22.7 0.0072 17.1 5.7 2.8 3 0 0 3 3 2 2 C2H2-type zinc finger zf-BED PF02892.15 ORY53753.1 - 0.0074 16.3 6.8 0.17 11.9 0.7 2.5 2 0 0 2 2 2 2 BED zinc finger Neogenin_C PF06583.12 ORY53753.1 - 0.01 15.7 1.6 0.012 15.5 1.6 1.2 1 0 0 1 1 1 1 Neogenin C-terminus zf-C2HC_2 PF13913.6 ORY53753.1 - 0.014 15.3 3.7 0.014 15.3 3.7 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_2 PF13465.6 ORY53753.1 - 0.031 14.7 17.9 0.13 12.8 0.4 3.7 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_2 PF12756.7 ORY53753.1 - 0.033 14.5 5.3 0.81 10.1 0.8 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_C2H2_6 PF18450.1 ORY53753.1 - 0.085 12.6 9.4 0.11 12.2 2.3 2.4 2 0 0 2 2 2 0 Zinc Finger domain Clr2_transil PF16761.5 ORY53753.1 - 0.1 13.5 5.1 0.19 12.5 5.1 1.5 1 1 0 1 1 1 0 Transcription-silencing protein, cryptic loci regulator Clr2 zf-MYST PF17772.1 ORY53753.1 - 0.23 11.1 4.6 0.82 9.3 0.8 2.3 2 0 0 2 2 2 0 MYST family zinc finger domain zf-C2H2_11 PF16622.5 ORY53753.1 - 2.2 8.1 10.8 1.7 8.4 0.7 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF629 PF04780.12 ORY53753.1 - 3 6.3 6.4 3.6 6.0 2.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF629) Sin3a_C PF16879.5 ORY53754.1 - 3.9e-73 246.7 0.7 2.8e-71 240.6 0.0 3.2 3 0 0 3 3 3 1 C-terminal domain of Sin3a protein PAH PF02671.21 ORY53754.1 - 6.9e-49 163.8 10.7 2e-17 63.0 2.2 4.5 3 1 1 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 ORY53754.1 - 4.7e-37 126.0 0.2 1.1e-36 124.8 0.2 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor COX5A PF02284.16 ORY53754.1 - 0.12 12.4 0.4 1.2e+02 2.7 0.0 3.9 4 0 0 4 4 4 0 Cytochrome c oxidase subunit Va PAN_3 PF08277.12 ORY53755.1 - 0.0048 16.7 0.6 0.0048 16.7 0.6 2.8 4 1 0 4 4 4 1 PAN-like domain DUF5401 PF17380.2 ORY53755.1 - 0.0063 14.7 5.8 0.0076 14.4 5.8 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5401) FSA_C PF10479.9 ORY53755.1 - 0.068 11.3 10.7 0.067 11.3 10.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SprA-related PF12118.8 ORY53755.1 - 0.16 11.1 9.2 0.2 10.8 9.2 1.1 1 0 0 1 1 1 0 SprA-related family HCV_NS5a_C PF12941.7 ORY53755.1 - 1.5 8.6 10.6 2.6 7.9 10.6 1.3 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region TMEM154 PF15102.6 ORY53755.1 - 2.1 8.2 10.9 3.4 7.6 10.9 1.3 1 0 0 1 1 1 0 TMEM154 protein family PP_M1 PF03012.14 ORY53755.1 - 6.5 6.2 8.1 9.4 5.7 8.1 1.1 1 0 0 1 1 1 0 Phosphoprotein PAH PF02671.21 ORY53756.1 - 0.00013 22.0 0.5 0.041 14.0 0.1 2.8 1 1 1 2 2 2 2 Paired amphipathic helix repeat Zn_clus PF00172.18 ORY53757.1 - 4.1e-08 33.2 7.7 5.7e-08 32.8 7.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 7tm_2 PF00002.24 ORY53758.1 - 1.5e-10 40.8 15.5 2.2e-10 40.3 15.5 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 ORY53758.1 - 2.7e-09 36.7 9.6 4.6e-09 36.0 9.6 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 ORY53758.1 - 0.00052 19.2 11.2 0.00052 19.2 11.2 2.0 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor DUF4834 PF16118.5 ORY53758.1 - 0.17 12.8 0.1 0.55 11.2 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SNARE PF05739.19 ORY53759.1 - 1.3e-12 47.5 0.8 1.3e-12 47.5 0.8 1.8 2 0 0 2 2 2 1 SNARE domain Syntaxin-5_N PF11416.8 ORY53759.1 - 1.1e-07 30.9 3.4 7.8e-07 28.2 0.6 2.7 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 ORY53759.1 - 5.1e-05 23.0 17.0 0.014 15.1 0.0 3.1 2 1 1 3 3 3 3 Syntaxin Syntaxin-18_N PF10496.9 ORY53759.1 - 0.0013 18.9 0.3 0.0013 18.9 0.3 3.0 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus BLOC1_2 PF10046.9 ORY53759.1 - 0.1 12.9 0.5 0.1 12.9 0.5 3.4 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF724 PF05266.14 ORY53759.1 - 0.16 11.8 11.7 0.44 10.3 4.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF724) DUF16 PF01519.16 ORY53759.1 - 4.4 7.9 14.4 0.25 11.8 1.2 2.7 2 1 0 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.12 ORY53759.1 - 5.3 7.7 15.4 1.3 9.7 3.9 3.5 2 1 1 3 3 3 0 SlyX Ribosomal_S21e PF01249.18 ORY53760.1 - 1e-38 131.3 0.0 1.1e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e RHS_repeat PF05593.14 ORY53760.1 - 0.062 13.8 0.7 4.8 7.8 0.1 2.9 3 0 0 3 3 3 0 RHS Repeat AAA PF00004.29 ORY53762.1 - 3.1e-11 43.8 0.0 6.1e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 ORY53762.1 - 1.1e-06 28.7 0.0 2.5e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 ORY53762.1 - 2.1e-06 27.8 0.1 7.4e-05 22.8 0.1 2.4 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 ORY53762.1 - 4e-05 23.9 0.1 0.00047 20.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 ORY53762.1 - 6e-05 23.5 0.0 0.032 14.6 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 ORY53762.1 - 0.00057 19.7 0.0 0.0012 18.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 ORY53762.1 - 0.007 16.0 0.1 0.27 10.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 ORY53762.1 - 0.016 15.0 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_assoc_2 PF16193.5 ORY53762.1 - 0.022 15.1 0.0 0.062 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA C-terminal domain AAA_5 PF07728.14 ORY53762.1 - 0.022 14.7 0.0 0.051 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 ORY53762.1 - 0.031 14.8 0.2 0.42 11.2 0.1 2.7 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.22 ORY53762.1 - 0.037 13.2 0.0 0.079 12.1 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 ORY53762.1 - 0.044 13.5 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 ORY53762.1 - 0.049 13.4 0.0 0.23 11.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 ORY53762.1 - 0.084 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 ORY53762.1 - 0.091 12.7 0.8 0.87 9.5 0.2 2.5 3 0 0 3 3 3 0 NACHT domain TsaE PF02367.17 ORY53762.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DEAD PF00270.29 ORY53762.1 - 0.12 12.1 0.1 6.7 6.4 0.0 2.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_33 PF13671.6 ORY53762.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 ORY53762.1 - 0.16 12.1 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) NTPase_1 PF03266.15 ORY53762.1 - 0.22 11.4 0.6 3.6 7.5 0.1 2.3 1 1 1 2 2 2 0 NTPase S-methyl_trans PF02574.16 ORY53763.1 - 2.3e-41 142.4 0.1 2.5e-41 142.3 0.1 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Mpv17_PMP22 PF04117.12 ORY53764.1 - 3.4e-21 75.2 0.7 5.6e-21 74.5 0.7 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF1372 PF07116.11 ORY53764.1 - 0.14 12.3 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1372) Amidohydro_2 PF04909.14 ORY53765.1 - 5.6e-16 59.2 0.0 8.8e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase ACBP PF00887.19 ORY53765.1 - 4.1e-08 33.3 0.7 9.2e-08 32.2 0.2 1.8 2 0 0 2 2 2 1 Acyl CoA binding protein 7tm_2 PF00002.24 ORY53766.1 - 1.1e-06 28.1 1.6 2e-06 27.3 1.6 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 ORY53766.1 - 1e-05 25.0 1.6 1.4e-05 24.5 1.6 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GPR_Gpa2_C PF11970.8 ORY53766.1 - 0.83 9.8 8.1 0.072 13.2 2.7 2.1 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUF3671 PF12420.8 ORY53766.1 - 1.1 9.4 6.4 0.33 11.0 2.8 2.0 2 0 0 2 2 2 0 Protein of unknown function 7tm_1 PF00001.21 ORY53767.1 - 6.9e-11 42.0 9.4 9.4e-11 41.5 9.4 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 ORY53767.1 - 9.5e-10 38.2 17.1 1.6e-09 37.4 17.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Git3 PF11710.8 ORY53767.1 - 0.0001 22.1 18.2 0.00017 21.4 18.2 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.11 ORY53767.1 - 0.00058 19.1 18.1 0.0013 17.9 18.1 1.6 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor Orbi_VP4 PF05059.12 ORY53767.1 - 0.014 13.5 2.2 0.019 13.0 2.2 1.1 1 0 0 1 1 1 0 Orbivirus VP4 core protein Ocular_alb PF02101.15 ORY53767.1 - 1.4 7.7 16.3 2.8 6.8 16.3 1.4 1 0 0 1 1 1 0 Ocular albinism type 1 protein Frizzled PF01534.17 ORY53768.1 - 0.00019 20.6 0.4 0.00021 20.4 0.4 1.0 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.24 ORY53768.1 - 0.00076 18.8 1.5 0.00076 18.8 1.5 1.0 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) PAH PF02671.21 ORY53770.1 - 5.5e-07 29.6 0.0 1.3e-06 28.5 0.0 1.6 2 0 0 2 2 2 1 Paired amphipathic helix repeat DHHC PF01529.20 ORY53771.1 - 2.4e-24 86.0 7.4 2.4e-24 86.0 7.4 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Lipase_3 PF01764.25 ORY53772.1 - 5.4e-19 68.5 0.0 2e-18 66.7 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 ORY53772.1 - 0.0095 15.2 0.0 0.026 13.8 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 ORY53772.1 - 0.1 13.2 2.1 0.33 11.5 2.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family ToxB_N PF18224.1 ORY53775.1 - 0.24 11.4 1.8 2.7 8.0 0.0 3.1 3 1 1 4 4 4 0 ToxB N-terminal domain Cyt-b5 PF00173.28 ORY53776.1 - 2.1e-11 43.8 0.0 1.5e-10 41.1 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.24 ORY53776.1 - 6e-10 39.4 13.1 6e-10 39.4 13.1 1.9 2 0 0 2 2 2 1 Fatty acid desaturase Phosphoesterase PF04185.14 ORY53778.1 - 2.8e-29 102.4 0.6 4.6e-28 98.4 0.2 2.3 1 1 1 2 2 2 1 Phosphoesterase family PEN-2 PF10251.9 ORY53779.1 - 0.19 12.1 1.6 14 6.2 0.0 2.5 3 0 0 3 3 3 0 Presenilin enhancer-2 subunit of gamma secretase DUF3810 PF12725.7 ORY53779.1 - 0.27 10.5 1.2 0.27 10.6 0.2 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) GCP_N_terminal PF17681.1 ORY53780.1 - 0.19 11.4 0.0 0.41 10.2 0.0 1.7 1 1 0 1 1 1 0 Gamma tubulin complex component N-terminal Mito_carr PF00153.27 ORY53780.1 - 0.75 9.8 3.0 3.6 7.6 0.0 2.7 3 0 0 3 3 3 0 Mitochondrial carrier protein Ribosomal_S19 PF00203.21 ORY53781.1 - 2.2e-34 117.2 0.4 2.6e-34 116.9 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 Aldedh PF00171.22 ORY53782.1 - 3.8e-125 418.0 0.0 4.2e-125 417.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AMP-binding PF00501.28 ORY53783.1 - 2.7e-87 293.1 0.0 3.5e-87 292.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 ORY53783.1 - 3.6e-17 63.1 0.0 9.7e-17 61.7 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Alpha_TIF PF02232.15 ORY53783.1 - 0.18 10.9 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) Velvet PF11754.8 ORY53784.1 - 5.9e-46 157.4 0.3 7.3e-30 104.7 0.0 2.4 1 1 1 2 2 2 2 Velvet factor Choline_transpo PF04515.12 ORY53785.1 - 1.4e-54 185.6 19.5 1.4e-54 185.6 19.5 2.3 1 1 2 3 3 3 2 Plasma-membrane choline transporter Arm PF00514.23 ORY53786.1 - 9e-60 197.0 22.2 4.7e-05 23.3 0.0 14.0 13 1 1 14 14 14 13 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 ORY53786.1 - 1.9e-18 66.6 19.8 7.8e-06 26.2 0.1 8.5 3 2 6 9 9 8 6 HEAT repeats HEAT PF02985.22 ORY53786.1 - 9.5e-13 47.2 13.1 0.29 11.5 0.1 9.1 11 0 0 11 11 10 4 HEAT repeat HEAT_EZ PF13513.6 ORY53786.1 - 1.4e-12 47.8 10.8 0.0022 18.5 0.2 9.5 8 1 1 9 9 9 3 HEAT-like repeat Arm_2 PF04826.13 ORY53786.1 - 2.6e-08 33.6 5.7 0.0063 16.0 0.0 5.9 3 2 3 6 6 6 2 Armadillo-like Adaptin_N PF01602.20 ORY53786.1 - 1.1e-07 30.8 8.3 0.0077 14.8 0.5 5.0 3 2 3 6 6 6 4 Adaptin N terminal region Cnd1 PF12717.7 ORY53786.1 - 2e-07 31.2 5.9 0.31 11.0 0.2 5.1 2 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 ORY53786.1 - 4.3e-07 30.1 5.3 0.25 11.4 0.1 6.7 1 1 7 8 8 8 2 V-ATPase subunit H KAP PF05804.12 ORY53786.1 - 4.4e-07 28.5 2.6 0.0011 17.2 0.6 3.6 2 1 1 3 3 3 2 Kinesin-associated protein (KAP) UNC45-central PF11701.8 ORY53786.1 - 5.9e-05 23.1 4.5 1.9 8.4 0.0 4.9 3 2 2 5 5 5 2 Myosin-binding striated muscle assembly central WAPL PF07814.13 ORY53786.1 - 0.00027 19.9 0.1 0.079 11.7 0.0 3.0 2 0 0 2 2 2 1 Wings apart-like protein regulation of heterochromatin V-ATPase_H_N PF03224.14 ORY53786.1 - 0.01 15.2 1.1 2 7.6 0.2 3.9 3 1 0 3 3 3 0 V-ATPase subunit H RasGEF_N_2 PF14663.6 ORY53786.1 - 0.015 15.7 5.3 1.6e+02 2.7 0.0 6.3 5 2 2 7 7 7 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Vac14_Fab1_bd PF12755.7 ORY53786.1 - 0.024 15.2 0.4 7.6 7.2 0.0 3.8 3 1 1 4 4 3 0 Vacuolar 14 Fab1-binding region DNA_pol_delta_4 PF04081.13 ORY53786.1 - 1.2 9.5 6.3 0.24 11.8 0.1 2.3 2 0 0 2 2 2 0 DNA polymerase delta, subunit 4 BSP_II PF05432.11 ORY53786.1 - 1.2 8.7 14.4 2.2 7.9 14.4 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) RICTOR_N PF14664.6 ORY53786.1 - 1.3 7.9 7.3 3.6 6.5 0.1 4.2 3 2 1 5 5 5 0 Rapamycin-insensitive companion of mTOR, N-term Aminotran_1_2 PF00155.21 ORY53787.1 - 5.3e-72 243.0 0.0 6.4e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.21 ORY53788.1 - 3e-31 108.9 0.2 4.5e-13 49.1 0.0 3.9 2 2 1 3 3 3 3 Aminotransferase class I and II CoA_transf_3 PF02515.17 ORY53788.1 - 0.15 11.1 0.0 17 4.4 0.0 2.4 2 0 0 2 2 2 0 CoA-transferase family III Methyltransf_16 PF10294.9 ORY53789.1 - 0.00023 20.9 0.2 0.0007 19.4 0.0 1.7 2 0 0 2 2 2 1 Lysine methyltransferase Velvet PF11754.8 ORY53790.1 - 3.5e-44 151.6 0.2 3.5e-44 151.6 0.2 2.4 2 1 0 2 2 2 1 Velvet factor MAP65_ASE1 PF03999.12 ORY53790.1 - 0.0054 15.5 2.6 0.0063 15.3 2.6 1.0 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Velvet PF11754.8 ORY53791.1 - 1.3e-46 159.6 5.8 1.3e-44 153.0 5.8 2.5 1 1 0 1 1 1 1 Velvet factor Velvet PF11754.8 ORY53792.1 - 6.1e-47 160.7 0.0 1.1e-45 156.5 0.0 2.1 1 1 0 1 1 1 1 Velvet factor Velvet PF11754.8 ORY53793.1 - 5.1e-44 151.1 2.5 1.4e-42 146.3 2.5 2.4 1 1 0 1 1 1 1 Velvet factor Velvet PF11754.8 ORY53794.1 - 5.9e-22 78.8 0.0 1.3e-20 74.4 0.1 2.0 1 1 1 2 2 2 2 Velvet factor Velvet PF11754.8 ORY53795.1 - 4.1e-21 76.1 0.0 1e-20 74.8 0.0 1.6 1 1 0 1 1 1 1 Velvet factor DnaJ_CXXCXGXG PF00684.19 ORY53796.1 - 4.6 7.7 15.0 0.56 10.6 5.0 2.3 1 1 1 2 2 2 0 DnaJ central domain DnaJ_CXXCXGXG PF00684.19 ORY53798.1 - 0.00074 19.8 22.6 0.00083 19.7 8.0 2.7 2 1 0 2 2 2 2 DnaJ central domain DnaJ PF00226.31 ORY53800.1 - 5.4e-07 29.7 0.0 1.5e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain LIM PF00412.22 ORY53800.1 - 0.097 12.9 1.5 18 5.6 0.8 2.8 2 1 1 3 3 3 0 LIM domain ADD_ATRX PF17981.1 ORY53800.1 - 0.44 10.5 2.4 0.44 10.4 0.6 1.9 2 0 0 2 2 2 0 Cysteine Rich ADD domain zf-FCS PF06467.14 ORY53800.1 - 1 9.4 4.4 0.37 10.8 0.6 2.2 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif FA_hydroxylase PF04116.13 ORY53801.1 - 7.6e-12 45.7 5.2 7.6e-12 45.7 5.2 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Palm_thioest PF02089.15 ORY53802.1 - 2.5e-77 260.0 0.0 2.8e-77 259.8 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 ORY53802.1 - 0.0072 15.9 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF915 PF06028.11 ORY53802.1 - 0.092 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) FSH1 PF03959.13 ORY53802.1 - 0.1 12.2 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF2059 PF09832.9 ORY53804.1 - 0.0017 18.3 0.0 0.0023 18.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2059) Velvet PF11754.8 ORY53806.1 - 4.6e-15 56.3 0.0 6.5e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Velvet factor Pribosyltran PF00156.27 ORY53807.1 - 4.2e-11 42.6 0.0 8.1e-11 41.7 0.0 1.4 1 1 1 2 2 2 1 Phosphoribosyl transferase domain Nbas_N PF15492.6 ORY53807.1 - 0.0048 16.3 0.0 0.0062 15.9 0.0 1.1 1 0 0 1 1 1 1 Neuroblastoma-amplified sequence, N terminal adh_short PF00106.25 ORY53809.1 - 4.9e-46 156.7 0.2 7.1e-46 156.1 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 ORY53809.1 - 1e-34 120.2 0.2 1.3e-34 119.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY53809.1 - 2.7e-15 56.7 0.0 3.7e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 ORY53809.1 - 0.012 15.0 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) GH3 PF03321.13 ORY53810.1 - 1.3e-66 225.5 0.0 2.2e-66 224.8 0.0 1.3 1 1 0 1 1 1 1 GH3 auxin-responsive promoter DUF4827 PF16109.5 ORY53811.1 - 0.034 14.1 0.7 0.07 13.1 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4827) GH3 PF03321.13 ORY53812.1 - 9.9e-65 219.4 0.0 7.6e-53 180.2 0.0 2.1 1 1 1 2 2 2 2 GH3 auxin-responsive promoter Lon_C PF05362.13 ORY53813.1 - 9.9e-68 227.7 0.0 1.9e-67 226.8 0.0 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 ORY53813.1 - 4.9e-32 111.5 0.9 9.9e-32 110.5 0.0 1.9 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 ORY53813.1 - 3.1e-23 82.6 0.0 7.6e-23 81.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 ORY53813.1 - 3.7e-08 33.5 0.0 9.9e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 ORY53813.1 - 1.4e-05 24.9 0.0 3.2e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase RuvB_N PF05496.12 ORY53813.1 - 0.00011 22.0 0.0 0.00072 19.3 0.0 2.4 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 ORY53813.1 - 0.00021 21.5 0.1 0.0026 18.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 ORY53813.1 - 0.00026 20.0 0.0 0.00055 18.9 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_2 PF07724.14 ORY53813.1 - 0.00079 19.6 0.0 0.003 17.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 ORY53813.1 - 0.0038 17.8 1.3 0.019 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 ORY53813.1 - 0.0076 16.6 0.1 0.03 14.7 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 ORY53813.1 - 0.021 14.8 0.1 0.072 13.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain SKI PF01202.22 ORY53813.1 - 0.022 14.9 0.6 0.084 13.0 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase AAA_33 PF13671.6 ORY53813.1 - 0.046 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 ORY53813.1 - 0.05 14.0 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 ORY53813.1 - 0.069 12.9 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 ORY53813.1 - 0.071 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.15 ORY53813.1 - 0.12 12.3 0.9 4.4 7.2 0.1 2.9 1 1 1 2 2 2 0 NTPase Mucin PF01456.17 ORY53814.1 - 0.011 15.8 20.0 0.026 14.5 20.0 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein tRNA_bind PF01588.20 ORY53815.1 - 3.3e-08 33.5 0.0 5.3e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain Epsilon_antitox PF08998.11 ORY53816.1 - 0.047 14.0 0.4 0.12 12.6 0.4 1.7 1 0 0 1 1 1 0 Bacterial epsilon antitoxin CAF-1_p150 PF11600.8 ORY53818.1 - 4.4 7.0 18.6 2.9 7.6 6.2 2.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-ZPR1 PF03367.13 ORY53819.1 - 2.8e-110 365.3 2.8 3.4e-55 186.3 0.0 2.3 2 0 0 2 2 2 2 ZPR1 zinc-finger domain APG12 PF04110.13 ORY53819.1 - 0.12 12.8 0.0 0.58 10.6 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-like autophagy protein Apg12 zinc-ribbons_6 PF07191.12 ORY53819.1 - 0.13 12.3 0.1 0.13 12.3 0.1 2.5 2 1 0 2 2 2 0 zinc-ribbons PP_kinase PF02503.17 ORY53819.1 - 0.13 11.9 0.0 13 5.3 0.0 2.4 2 0 0 2 2 2 0 Polyphosphate kinase middle domain RNA_POL_M_15KD PF02150.16 ORY53819.1 - 0.54 10.2 4.4 1.4 8.9 0.0 2.8 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit zn-ribbon_14 PF16503.5 ORY53819.1 - 6.3 6.4 10.2 6 6.5 0.3 3.4 3 0 0 3 3 3 0 Zinc-ribbon TP_methylase PF00590.20 ORY53821.1 - 4.8e-25 88.8 0.0 7.6e-25 88.1 0.0 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases ABC_tran PF00005.27 ORY53822.1 - 1.3e-43 148.8 0.1 2.7e-31 108.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 ORY53822.1 - 6.9e-35 120.8 73.3 2.8e-22 79.3 23.0 3.2 2 1 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 ORY53822.1 - 1.5e-09 38.1 0.5 0.00011 22.1 0.0 3.5 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 ORY53822.1 - 1.1e-06 28.2 19.5 1.1e-06 28.2 19.5 4.4 2 1 1 3 3 3 1 ABC-2 type transporter SMC_N PF02463.19 ORY53822.1 - 0.0017 17.8 0.3 0.59 9.5 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 ORY53822.1 - 0.023 14.8 0.1 0.053 13.6 0.1 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain SbcCD_C PF13558.6 ORY53822.1 - 0.053 13.8 0.1 1.8 8.8 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit CLP1_P PF16575.5 ORY53822.1 - 0.086 12.6 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_23 PF13476.6 ORY53822.1 - 0.19 12.2 0.6 0.56 10.7 0.6 1.7 1 0 0 1 1 1 0 AAA domain SET PF00856.28 ORY53823.1 - 9.6e-15 55.4 0.0 2.5e-14 54.0 0.0 1.8 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 ORY53823.1 - 1.2e-05 25.3 6.7 1.2e-05 25.3 6.7 3.6 4 0 0 4 4 4 1 MYND finger TPR_16 PF13432.6 ORY53823.1 - 0.0011 19.5 0.2 0.17 12.5 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2318 PF10080.9 ORY53823.1 - 0.13 12.4 0.1 0.13 12.4 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) ArfGap PF01412.18 ORY53825.1 - 2.6e-25 88.7 0.5 2.9e-25 88.6 0.5 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-dskA_traR PF01258.17 ORY53825.1 - 0.15 12.0 0.9 6.3 6.8 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Sybindin PF04099.12 ORY53826.1 - 2e-26 92.6 0.3 2.2e-26 92.5 0.3 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 ORY53826.1 - 1.4e-06 28.5 0.4 1.5e-06 28.4 0.4 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region PI_PP_C PF18365.1 ORY53826.1 - 0.036 14.0 0.1 0.066 13.2 0.0 1.4 2 0 0 2 2 2 0 Phosphoinositide phosphatase C-terminal domain NDUF_B7 PF05676.13 ORY53827.1 - 4.9e-28 96.6 6.1 6e-28 96.4 6.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 ORY53827.1 - 0.026 14.6 3.7 0.046 13.8 3.6 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like adh_short PF00106.25 ORY53829.1 - 2.8e-36 124.8 9.0 6.4e-24 84.5 2.9 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 ORY53829.1 - 7.6e-34 117.3 6.3 1.4e-31 109.9 6.3 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 ORY53829.1 - 5.8e-10 39.4 1.3 8.8e-10 38.8 1.3 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 ORY53829.1 - 0.0085 15.6 0.9 0.044 13.2 0.9 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 ORY53829.1 - 0.0088 15.9 1.6 0.015 15.2 1.6 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1815 PF08844.10 ORY53829.1 - 0.067 13.2 0.1 0.16 12.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1815) GDP_Man_Dehyd PF16363.5 ORY53829.1 - 0.11 11.8 0.3 0.5 9.7 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase ATP-synt PF00231.19 ORY53830.1 - 6.8e-73 245.8 10.1 7.8e-73 245.6 10.1 1.0 1 0 0 1 1 1 1 ATP synthase DUF3549 PF12069.8 ORY53830.1 - 0.012 14.6 1.2 0.024 13.7 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3549) OPA3 PF07047.12 ORY53831.1 - 3.1e-35 120.7 1.9 5.4e-35 119.9 1.9 1.5 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) Ax_dynein_light PF10211.9 ORY53831.1 - 0.0056 16.6 0.3 0.0087 16.0 0.3 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain PDEase_I PF00233.19 ORY53833.1 - 6e-51 173.5 9.0 2.9e-31 109.0 1.5 3.2 2 1 1 3 3 3 2 3'5'-cyclic nucleotide phosphodiesterase DUF3881 PF12997.7 ORY53833.1 - 0.067 12.4 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) RNase_T PF00929.24 ORY53834.1 - 3.4e-17 63.5 0.3 1.1e-16 61.8 0.0 1.8 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.20 ORY53834.1 - 0.0081 15.9 0.1 0.046 13.4 0.1 2.2 1 1 1 2 2 2 1 3'-5' exonuclease ATP-synt_J PF04911.12 ORY53835.1 - 0.18 11.4 0.5 0.42 10.2 0.5 1.6 1 0 0 1 1 1 0 ATP synthase j chain Sporozoite_P67 PF05642.11 ORY53835.1 - 0.22 9.6 2.0 0.26 9.4 2.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.6 ORY53835.1 - 0.27 11.6 6.8 0.46 10.9 6.8 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cwf_Cwc_15 PF04889.12 ORY53835.1 - 0.69 9.6 9.1 0.95 9.1 9.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Atg31 PF09795.9 ORY53835.1 - 0.79 9.7 4.3 1.6 8.7 4.3 1.5 1 1 0 1 1 1 0 Autophagy-related protein 31 NOA36 PF06524.12 ORY53835.1 - 2.9 7.1 5.8 3.6 6.8 5.8 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 ORY53835.1 - 4.8 5.1 7.7 6.4 4.7 7.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi RRM_1 PF00076.22 ORY53836.1 - 4.8e-07 29.5 0.0 8.8e-06 25.5 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_2 PF07724.14 ORY53837.1 - 6.7e-41 140.2 0.1 1.3e-37 129.6 0.0 3.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.9 ORY53837.1 - 1.4e-21 76.3 0.4 1.4e-21 76.3 0.4 3.2 3 0 0 3 3 3 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 ORY53837.1 - 4.9e-18 65.8 0.0 2.2e-08 34.6 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.20 ORY53837.1 - 6.8e-17 61.3 0.0 7e-08 32.5 0.0 3.0 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_lid_9 PF17871.1 ORY53837.1 - 9.3e-16 57.6 8.8 7.3e-08 32.3 1.7 3.8 2 1 1 3 3 3 2 AAA lid domain AAA_5 PF07728.14 ORY53837.1 - 4.6e-13 49.4 2.4 7.3e-08 32.5 0.2 4.3 2 2 1 3 3 3 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 ORY53837.1 - 4e-08 33.2 0.1 7.9e-05 22.4 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 ORY53837.1 - 3.2e-05 24.4 7.1 0.0063 16.9 0.0 4.8 3 2 1 5 5 5 1 AAA ATPase domain RuvB_N PF05496.12 ORY53837.1 - 6.2e-05 22.8 0.7 0.23 11.2 0.0 3.8 2 2 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain EzrA PF06160.12 ORY53837.1 - 0.00081 17.7 4.0 0.0014 16.9 4.0 1.3 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA AAA_22 PF13401.6 ORY53837.1 - 0.00097 19.4 0.7 0.42 10.9 0.1 3.9 2 2 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 ORY53837.1 - 0.0011 18.3 0.2 0.1 12.0 0.0 2.9 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 ORY53837.1 - 0.0093 16.5 0.3 0.41 11.2 0.3 3.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 ORY53837.1 - 0.019 14.7 0.2 0.17 11.6 0.1 2.5 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 ORY53837.1 - 0.036 13.6 0.0 4 6.9 0.0 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region DNA_pol3_delta2 PF13177.6 ORY53837.1 - 0.077 12.8 0.0 23 4.8 0.0 2.8 3 0 0 3 3 3 0 DNA polymerase III, delta subunit ZnuA PF01297.17 ORY53837.1 - 0.11 11.8 0.7 0.42 10.0 0.2 2.2 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic LOH1CR12 PF10158.9 ORY53837.1 - 0.11 12.5 0.7 0.4 10.7 0.7 1.9 1 0 0 1 1 1 0 Tumour suppressor protein Spc7 PF08317.11 ORY53837.1 - 0.64 8.8 10.0 1.4 7.7 10.0 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4061 PF13270.6 ORY53837.1 - 1.5 9.2 5.4 15 6.0 0.1 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) Fmp27_WPPW PF10359.9 ORY53837.1 - 1.9 7.3 5.0 0.63 8.8 2.2 1.6 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Cep57_CLD_2 PF14197.6 ORY53837.1 - 2.1 8.5 10.5 10 6.3 1.5 2.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 BLOC1_2 PF10046.9 ORY53837.1 - 3.2 8.1 9.0 0.57 10.5 3.0 3.1 4 0 0 4 4 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Occludin_ELL PF07303.13 ORY53837.1 - 9.7 7.0 7.0 6.4 7.6 3.9 2.4 2 0 0 2 2 1 0 Occludin homology domain ASH PF15780.5 ORY53838.1 - 5.5e-38 129.1 18.7 1.2e-05 25.4 0.0 10.7 11 0 0 11 11 11 7 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 ORY53838.1 - 1.2e-19 70.1 16.1 0.00033 20.5 0.1 10.0 11 0 0 11 11 11 6 MSP (Major sperm protein) domain MYCBPAP PF14646.6 ORY53838.1 - 4.3e-07 29.2 1.0 0.025 13.5 0.0 6.3 6 1 1 7 7 7 2 MYCBP-associated protein family DUF1573 PF07610.11 ORY53838.1 - 5.5e-07 29.5 7.9 0.13 12.3 0.1 8.4 8 0 0 8 8 8 1 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 ORY53838.1 - 0.00015 21.9 6.0 1.3 9.4 0.1 6.8 7 0 0 7 7 7 1 Transmembrane protein 131-like PapD-like PF14874.6 ORY53838.1 - 0.00033 20.8 1.9 5.3 7.3 0.0 4.8 5 0 0 5 5 5 2 Flagellar-associated PapD-like fn3_5 PF06280.12 ORY53838.1 - 0.00061 20.5 1.2 2.6 8.8 0.0 5.8 7 1 0 7 7 7 1 Fn3-like domain GST_C PF00043.25 ORY53840.1 - 1.5e-07 31.6 0.0 2.2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 ORY53840.1 - 5.5e-06 26.5 0.1 1.5e-05 25.1 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 ORY53840.1 - 4e-05 23.5 0.0 7.4e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 ORY53840.1 - 0.0026 18.0 0.0 0.0052 17.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 ORY53840.1 - 0.081 13.3 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Peptidase_S8 PF00082.22 ORY53841.1 - 7.5e-44 150.2 5.2 1.1e-43 149.6 5.2 1.3 1 0 0 1 1 1 1 Subtilase family fn3_5 PF06280.12 ORY53841.1 - 5.4e-07 30.3 0.9 1.4e-06 29.0 0.9 1.8 1 0 0 1 1 1 1 Fn3-like domain PA PF02225.22 ORY53841.1 - 2.2e-05 24.4 0.4 2.2e-05 24.4 0.4 2.5 3 0 0 3 3 3 1 PA domain NPCBM_assoc PF10633.9 ORY53841.1 - 0.043 14.1 0.3 0.22 11.8 0.0 2.3 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase HTH_21 PF13276.6 ORY53842.1 - 0.15 12.2 2.7 0.18 12.0 0.1 2.4 3 0 0 3 3 3 0 HTH-like domain PHD_4 PF16866.5 ORY53842.1 - 9.6 6.4 13.6 6.8 6.9 5.8 3.4 3 0 0 3 3 3 0 PHD-finger Alpha_kinase PF02816.18 ORY53843.1 - 8.8e-19 68.3 1.0 1.1e-18 68.0 0.2 1.6 2 0 0 2 2 2 1 Alpha-kinase family Velvet PF11754.8 ORY53845.1 - 1.6e-27 97.0 0.0 1.9e-27 96.8 0.0 1.0 1 0 0 1 1 1 1 Velvet factor Glyco_hydro_1 PF00232.18 ORY53846.1 - 6.5e-90 301.7 0.1 2.4e-87 293.3 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 YqfQ PF14181.6 ORY53846.1 - 0.31 11.2 3.9 0.58 10.3 3.9 1.4 1 0 0 1 1 1 0 YqfQ-like protein Pex19 PF04614.12 ORY53847.1 - 3.7e-49 167.7 10.1 4e-49 167.6 10.1 1.0 1 0 0 1 1 1 1 Pex19 protein family GET2 PF08690.10 ORY53847.1 - 0.039 13.6 6.5 0.064 12.9 6.5 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 DUF4175 PF13779.6 ORY53847.1 - 0.043 11.7 3.6 0.071 11.0 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF148 PF02520.17 ORY53847.1 - 0.058 13.5 3.3 5.3 7.2 1.1 2.3 2 1 0 2 2 2 0 Domain of unknown function DUF148 MSC PF09402.10 ORY53847.1 - 0.11 12.0 0.9 0.13 11.7 0.9 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain Rrn6 PF10214.9 ORY53847.1 - 0.27 9.7 1.3 0.29 9.6 1.3 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor BST2 PF16716.5 ORY53847.1 - 0.28 11.8 5.1 2.3 8.9 2.5 2.2 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 HIT PF01230.23 ORY53849.1 - 0.025 15.3 0.0 0.078 13.7 0.0 1.7 2 0 0 2 2 2 0 HIT domain DUF4523 PF15023.6 ORY53849.1 - 0.058 13.2 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) RRM_1 PF00076.22 ORY53849.1 - 0.066 13.0 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_18 PF00704.28 ORY53850.1 - 5.1e-58 197.2 2.7 7.3e-58 196.7 2.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_19 PF00182.19 ORY53850.1 - 6.5e-18 65.5 1.3 6.5e-18 65.5 1.3 2.1 2 1 0 2 2 2 1 Chitinase class I zf-C2H2 PF00096.26 ORY53851.1 - 3.6e-08 33.4 5.2 0.0014 19.0 0.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 ORY53851.1 - 2.3e-07 30.9 3.1 0.00071 19.8 0.2 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 ORY53851.1 - 3.3e-07 30.6 5.5 0.00022 21.8 0.5 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.7 ORY53851.1 - 8e-07 29.3 2.0 0.003 17.9 0.2 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 ORY53851.1 - 7.7e-06 25.8 1.4 0.0044 17.0 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 ORY53851.1 - 0.00012 21.7 0.9 0.018 14.8 0.0 2.6 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-H2C2_2 PF13465.6 ORY53851.1 - 0.0024 18.2 0.3 0.0024 18.2 0.3 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf_C2H2_ZHX PF18387.1 ORY53851.1 - 0.0089 15.7 0.8 0.04 13.6 0.1 2.2 1 1 1 2 2 2 1 Zinc-fingers and homeoboxes C2H2 finger domain DUF678 PF05077.12 ORY53851.1 - 0.12 12.6 1.6 0.21 11.7 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF678) zf-C2H2_2 PF12756.7 ORY53851.1 - 0.17 12.3 3.2 0.32 11.4 0.7 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Yippee-Mis18 PF03226.14 ORY53851.1 - 0.17 12.1 1.1 0.44 10.8 0.0 2.1 3 0 0 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-BED PF02892.15 ORY53851.1 - 3.9 7.6 9.9 0.16 12.1 1.3 3.1 4 1 0 4 4 4 0 BED zinc finger zf-C2H2 PF00096.26 ORY53852.1 - 9.4e-08 32.1 16.3 4.4e-05 23.7 0.2 3.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 ORY53852.1 - 1.2e-06 28.9 16.1 0.00037 21.1 0.3 3.5 4 0 0 4 4 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 ORY53852.1 - 1.7e-06 27.9 2.6 0.017 15.1 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 ORY53852.1 - 4.1e-06 27.0 5.0 0.011 16.1 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 ORY53852.1 - 2.8e-05 24.3 8.7 0.0048 17.2 0.2 3.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 ORY53852.1 - 0.023 15.4 3.0 0.083 13.6 1.0 2.6 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 ORY53852.1 - 0.024 15.1 7.7 1.5 9.4 0.2 3.9 4 0 0 4 4 3 0 Zinc-finger double domain zf-BED PF02892.15 ORY53852.1 - 0.047 13.7 4.4 0.68 10.0 0.3 3.0 3 0 0 3 3 3 0 BED zinc finger zf-C2H2_2 PF12756.7 ORY53852.1 - 0.073 13.4 3.5 5 7.5 0.5 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) NopRA1 PF16201.5 ORY53852.1 - 0.21 11.2 1.2 0.25 10.9 0.1 1.6 2 0 0 2 2 2 0 Nucleolar pre-ribosomal-associated protein 1 zf-AN1 PF01428.16 ORY53852.1 - 0.25 11.5 1.4 2.8 8.2 0.2 2.3 2 0 0 2 2 2 0 AN1-like Zinc finger Actin_micro PF17003.5 ORY53852.1 - 0.27 10.4 1.8 0.54 9.4 1.8 1.5 1 1 0 1 1 1 0 Putative actin-like family zf-MYST PF17772.1 ORY53852.1 - 0.4 10.3 1.7 1.6 8.4 0.0 2.7 2 1 1 3 3 3 0 MYST family zinc finger domain zf-met2 PF12907.7 ORY53852.1 - 0.46 10.7 3.6 0.33 11.1 0.7 2.3 2 0 0 2 2 2 0 Zinc-binding zf-C2H2_11 PF16622.5 ORY53852.1 - 0.5 10.2 0.0 0.5 10.2 0.0 3.1 3 0 0 3 3 3 0 zinc-finger C2H2-type CTP_transf_like PF01467.26 ORY53853.1 - 1.1e-16 61.3 0.0 1.8e-16 60.6 0.0 1.4 1 1 0 1 1 1 1 Cytidylyltransferase-like VSP PF03302.13 ORY53854.1 - 0.00057 18.9 14.6 0.00057 18.9 14.6 2.2 1 1 1 2 2 2 1 Giardia variant-specific surface protein LPMO_10 PF03067.15 ORY53854.1 - 0.0031 18.2 2.3 0.0084 16.8 0.1 2.7 2 1 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Stevor PF17410.2 ORY53854.1 - 0.0031 17.1 3.5 0.0031 17.1 3.5 1.7 1 1 1 2 2 2 1 Subtelomeric Variable Open Reading frame PTP_tm PF18861.1 ORY53854.1 - 0.0044 17.0 3.4 0.0052 16.8 2.2 1.8 2 1 0 2 2 2 1 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF5336 PF17270.2 ORY53854.1 - 0.0059 16.2 6.8 0.011 15.4 6.8 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5336) DUF202 PF02656.15 ORY53854.1 - 0.016 15.6 4.2 0.065 13.7 4.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF2062 PF09835.9 ORY53854.1 - 0.083 12.7 1.0 0.6 10.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) PMP1_2 PF08114.11 ORY53854.1 - 0.11 12.3 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 ATPase proteolipid family RIFIN PF02009.16 ORY53854.1 - 0.59 10.0 4.4 0.89 9.4 4.4 1.2 1 0 0 1 1 1 0 Rifin VSP PF03302.13 ORY53856.1 - 0.00086 18.3 7.0 0.00086 18.3 7.0 1.5 2 0 0 2 2 2 1 Giardia variant-specific surface protein PTP_tm PF18861.1 ORY53856.1 - 0.023 14.7 4.1 0.022 14.8 2.9 1.7 1 1 1 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J CD99L2 PF12301.8 ORY53856.1 - 1.9 8.7 5.5 0.64 10.3 1.3 2.2 1 1 0 2 2 2 0 CD99 antigen like protein 2 TPPK_C PF12555.8 ORY53856.1 - 2.2 8.4 7.5 0.19 11.8 1.7 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Dicty_REP PF05086.12 ORY53856.1 - 7.4 4.4 7.9 9.5 4.0 7.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein LPMO_10 PF03067.15 ORY53857.1 - 0.0049 17.5 0.0 0.0049 17.5 0.0 2.4 2 2 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Aminotran_4 PF01063.19 ORY53858.1 - 3.1e-26 92.6 0.0 3.8e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Fer2 PF00111.27 ORY53859.1 - 1.4e-10 41.0 0.2 2e-10 40.5 0.2 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain MCR PF18509.1 ORY53859.1 - 0.074 12.6 0.1 0.2 11.3 0.1 1.8 1 0 0 1 1 1 0 Magnetochrome domain 5_nucleotid_C PF02872.18 ORY53862.1 - 2.3e-10 40.9 0.0 4.4e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain EF-hand_1 PF00036.32 ORY53862.1 - 6.6e-10 37.8 0.1 2.7e-05 23.4 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 ORY53862.1 - 1.1e-09 38.6 0.0 2.2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 ORY53862.1 - 4.7e-08 32.2 0.6 1.5e-06 27.4 0.2 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 ORY53862.1 - 2.3e-07 30.2 0.1 3.6e-05 23.3 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 ORY53862.1 - 4.3e-05 23.3 0.1 0.00011 21.9 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair Metallophos PF00149.28 ORY53862.1 - 0.00027 21.5 0.0 0.00049 20.7 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SPARC_Ca_bdg PF10591.9 ORY53862.1 - 0.045 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region IL3 PF02059.15 ORY53863.1 - 0.00069 19.7 0.2 0.0017 18.4 0.2 1.5 1 0 0 1 1 1 1 Interleukin-3 ATG2_CAD PF13329.6 ORY53864.1 - 0.052 13.3 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif DUF3826 PF12875.7 ORY53864.1 - 0.15 12.2 0.0 0.77 9.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3826) EF_TS PF00889.19 ORY53865.1 - 3e-17 62.9 0.2 9.3e-17 61.3 0.0 2.0 2 1 0 2 2 2 1 Elongation factor TS HemY_N PF07219.13 ORY53865.1 - 1.4 9.2 5.4 2.2 8.5 3.6 2.1 2 0 0 2 2 2 0 HemY protein N-terminus KxDL PF10241.9 ORY53866.1 - 0.00077 19.7 1.5 0.44 10.8 0.3 2.7 2 0 0 2 2 2 2 Uncharacterized conserved protein DivIC PF04977.15 ORY53866.1 - 0.016 14.9 3.9 0.11 12.2 0.0 2.3 2 0 0 2 2 2 0 Septum formation initiator APG6_N PF17675.1 ORY53866.1 - 0.033 14.7 3.5 7.6 7.1 0.0 2.6 2 1 0 2 2 2 0 Apg6 coiled-coil region Wtap PF17098.5 ORY53866.1 - 0.036 14.0 0.5 9.5 6.1 0.0 2.3 2 0 0 2 2 2 0 WTAP/Mum2p family DHR10 PF18595.1 ORY53866.1 - 0.05 13.7 3.0 2.1 8.4 0.2 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain GAS PF13851.6 ORY53866.1 - 0.05 12.9 3.7 0.71 9.2 0.1 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 ORY53866.1 - 0.056 13.3 3.5 0.11 12.3 0.3 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Prefoldin PF02996.17 ORY53866.1 - 0.16 11.9 2.7 5.6 6.9 0.1 3.0 3 0 0 3 3 3 0 Prefoldin subunit DUF1664 PF07889.12 ORY53866.1 - 0.2 11.7 1.7 2.8 8.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NYD-SP28 PF14772.6 ORY53866.1 - 0.21 11.7 3.2 0.26 11.4 0.4 2.1 2 0 0 2 2 2 0 Sperm tail Prefoldin_2 PF01920.20 ORY53866.1 - 0.37 10.8 8.7 3.2 7.7 0.2 2.9 3 0 0 3 3 3 0 Prefoldin subunit FlaC_arch PF05377.11 ORY53866.1 - 0.78 10.2 4.6 0.92 9.9 0.3 2.9 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Occludin_ELL PF07303.13 ORY53866.1 - 2.1 9.1 5.0 7.6 7.3 0.4 2.9 2 1 1 3 3 3 0 Occludin homology domain ABC_tran PF00005.27 ORY53867.1 - 3.9e-25 89.0 0.0 6.8e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 ORY53867.1 - 5.2e-14 52.1 13.0 5.2e-14 52.1 13.0 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 ORY53867.1 - 3.1e-06 27.2 0.4 1.4e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 ORY53867.1 - 3.5e-05 23.3 15.2 5.2e-05 22.8 10.8 2.5 2 0 0 2 2 2 1 ABC-2 type transporter RsgA_GTPase PF03193.16 ORY53867.1 - 4.2e-05 23.5 0.0 8.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 ORY53867.1 - 0.0028 16.8 0.0 0.005 15.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein SMC_N PF02463.19 ORY53867.1 - 0.038 13.4 0.0 0.1 12.0 0.0 1.3 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 ORY53867.1 - 0.12 12.9 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 ORY53867.1 - 0.18 11.0 0.2 0.46 9.7 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.6 ORY53867.1 - 0.22 11.2 0.0 0.76 9.4 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Chromate_transp PF02417.15 ORY53868.1 - 1.4e-45 155.2 38.6 6.6e-23 81.6 15.4 2.2 2 0 0 2 2 2 2 Chromate transporter COPI_assoc PF08507.10 ORY53868.1 - 7.2 6.7 13.8 55 3.8 9.9 3.5 2 1 0 2 2 2 0 COPI associated protein Chromate_transp PF02417.15 ORY53869.1 - 2.3e-48 164.3 28.3 2.1e-30 105.9 18.8 2.2 2 0 0 2 2 2 2 Chromate transporter Phosphodiest PF01663.22 ORY53870.1 - 3.7e-19 69.5 0.5 5.5e-19 69.0 0.5 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 ORY53870.1 - 1.4e-07 31.2 0.1 9.4e-06 25.2 0.0 2.9 2 1 0 2 2 2 1 Sulfatase Gti1_Pac2 PF09729.9 ORY53871.1 - 0.00019 21.6 8.8 0.00097 19.3 0.0 3.7 2 2 1 3 3 3 2 Gti1/Pac2 family DUF1179 PF06678.11 ORY53871.1 - 8.5 6.4 7.2 0.5 10.4 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) Gti1_Pac2 PF09729.9 ORY53872.1 - 4e-26 92.2 0.0 2.2e-20 73.5 0.0 2.5 2 1 1 3 3 3 2 Gti1/Pac2 family DUF2724 PF10893.8 ORY53872.1 - 0.2 11.5 1.0 0.61 10.0 1.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2724) Gti1_Pac2 PF09729.9 ORY53873.1 - 0.054 13.6 0.1 0.68 10.0 0.0 2.0 2 0 0 2 2 2 0 Gti1/Pac2 family KAR9 PF08580.10 ORY53873.1 - 3.4 6.1 8.7 3.9 5.9 8.7 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 PAT1 PF09770.9 ORY53873.1 - 5.8 5.1 8.2 6.8 4.8 8.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pex14_N PF04695.13 ORY53873.1 - 9.4 6.9 16.2 13 6.4 16.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Gti1_Pac2 PF09729.9 ORY53874.1 - 9.9e-22 77.9 6.9 1.5e-18 67.6 0.0 3.1 2 1 1 3 3 3 2 Gti1/Pac2 family FAM60A PF15396.6 ORY53874.1 - 0.047 13.7 2.8 0.078 13.0 2.8 1.3 1 0 0 1 1 1 0 Protein Family FAM60A SUIM_assoc PF16619.5 ORY53874.1 - 0.59 10.2 22.4 43 4.3 0.0 2.6 1 1 1 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF932 PF06067.11 ORY53874.1 - 0.85 9.3 7.4 1.3 8.8 7.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF932) TFIIA PF03153.13 ORY53874.1 - 5.3 6.9 25.0 7.3 6.5 25.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit p450 PF00067.22 ORY53875.1 - 4.6e-31 108.1 0.0 2.9e-30 105.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 YhfT PF10797.9 ORY53875.1 - 0.076 12.1 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function EcoEI_R_C PF08463.10 ORY53875.1 - 0.15 12.2 0.1 6.3 6.9 0.0 2.3 2 0 0 2 2 2 0 EcoEI R protein C-terminal Gti1_Pac2 PF09729.9 ORY53876.1 - 8.5e-25 87.9 1.2 1.7e-19 70.6 0.0 3.2 2 1 1 3 3 3 2 Gti1/Pac2 family SelP_N PF04592.14 ORY53876.1 - 0.47 9.8 9.8 0.78 9.1 9.8 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TFIIA PF03153.13 ORY53876.1 - 0.95 9.4 12.2 1.5 8.7 12.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gti1_Pac2 PF09729.9 ORY53877.1 - 2.5e-08 34.2 0.0 3e-05 24.2 0.0 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family PRIMA1 PF16101.5 ORY53877.1 - 4.3 7.4 15.8 7.4 6.6 3.6 2.6 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Gti1_Pac2 PF09729.9 ORY53878.1 - 4e-10 40.1 0.1 4e-10 40.1 0.1 1.0 1 0 0 1 1 1 1 Gti1/Pac2 family Gti1_Pac2 PF09729.9 ORY53879.1 - 6e-23 81.9 0.0 3.1e-18 66.5 0.0 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Gti1_Pac2 PF09729.9 ORY53880.1 - 8e-07 29.3 0.0 9.5e-07 29.1 0.0 1.3 1 1 0 1 1 1 1 Gti1/Pac2 family Gti1_Pac2 PF09729.9 ORY53881.1 - 2.2e-21 76.8 0.0 1.7e-19 70.6 0.0 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Gti1_Pac2 PF09729.9 ORY53882.1 - 2.5e-22 79.9 0.0 3.1e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Gti1/Pac2 family Tht1 PF04163.12 ORY53882.1 - 0.075 11.8 0.1 0.093 11.5 0.1 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein Gti1_Pac2 PF09729.9 ORY53883.1 - 4.6e-15 56.2 0.0 8.2e-12 45.6 0.0 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family Gti1_Pac2 PF09729.9 ORY53884.1 - 4.3e-13 49.8 2.2 2.8e-12 47.1 0.0 2.1 2 0 0 2 2 2 2 Gti1/Pac2 family Gti1_Pac2 PF09729.9 ORY53885.1 - 2.9e-15 56.8 0.1 1e-13 51.8 0.0 2.7 2 1 1 3 3 3 2 Gti1/Pac2 family Gti1_Pac2 PF09729.9 ORY53886.1 - 3.2e-20 73.0 0.5 4.5e-16 59.5 0.2 2.3 1 1 0 2 2 2 2 Gti1/Pac2 family Gti1_Pac2 PF09729.9 ORY53887.1 - 1.1e-18 67.9 0.0 2.6e-15 57.0 0.0 2.2 1 1 1 2 2 2 2 Gti1/Pac2 family Gti1_Pac2 PF09729.9 ORY53888.1 - 9.4e-12 45.4 0.0 1.8e-08 34.7 0.0 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Gti1_Pac2 PF09729.9 ORY53889.1 - 0.12 12.4 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family DnaJ PF00226.31 ORY53890.1 - 6.4e-19 67.8 1.0 1.4e-18 66.8 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 ORY53890.1 - 3.6e-17 62.4 0.0 5.6e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain ArfGap PF01412.18 ORY53892.1 - 4.4e-26 91.3 0.5 5.7e-26 90.9 0.5 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf-dskA_traR PF01258.17 ORY53892.1 - 0.19 11.7 2.1 7.9 6.5 0.1 2.4 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger PAT1 PF09770.9 ORY53893.1 - 2 6.6 30.2 2.5 6.3 30.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pollen_allerg_2 PF01620.16 ORY53895.1 - 0.11 12.6 0.0 1.3 9.2 0.0 2.1 2 0 0 2 2 2 0 Ribonuclease (pollen allergen) I_LWEQ PF01608.17 ORY53898.1 - 7.1e-29 101.0 5.3 1.3e-28 100.2 0.6 2.5 2 0 0 2 2 2 1 I/LWEQ domain FERM_M PF00373.18 ORY53898.1 - 1.8e-17 63.8 0.0 5.1e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 FERM central domain Gti1_Pac2 PF09729.9 ORY53898.1 - 9.6e-14 51.9 0.8 3.3e-08 33.9 0.0 2.8 2 1 1 3 3 3 2 Gti1/Pac2 family Focal_AT PF03623.13 ORY53898.1 - 0.085 12.9 0.6 0.45 10.5 0.0 2.4 2 0 0 2 2 2 0 Focal adhesion targeting region DD_K PF12121.8 ORY53898.1 - 0.96 9.6 4.2 1.8 8.8 4.2 1.5 1 0 0 1 1 1 0 Dermaseptin DUF2277 PF10041.9 ORY53898.1 - 1.4 9.3 3.9 15 6.0 0.5 3.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2277) zf-CCHH PF10283.9 ORY53899.1 - 0.095 12.7 0.1 3 7.9 0.2 2.5 2 0 0 2 2 2 0 PBZ domain RA PF00788.23 ORY53900.1 - 1.2e-06 29.1 0.0 2.6e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.28 ORY53900.1 - 2.1e-05 24.0 0.0 2.1e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_3 PF08239.11 ORY53900.1 - 0.034 14.4 0.2 0.081 13.2 0.2 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain AAA PF00004.29 ORY53901.1 - 6.2e-18 65.5 0.0 1.1e-17 64.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 ORY53901.1 - 7e-17 61.6 0.0 3e-16 59.6 0.0 2.0 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 ORY53901.1 - 2.6e-15 56.6 0.0 3e-12 46.6 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 ORY53901.1 - 6.5e-07 29.4 0.0 3.2e-06 27.2 0.0 1.8 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 ORY53901.1 - 4.3e-06 26.8 0.1 1.3e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 ORY53901.1 - 2.1e-05 24.3 0.1 6.6e-05 22.7 0.0 2.0 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_assoc_2 PF16193.5 ORY53901.1 - 7.5e-05 23.0 0.0 0.00019 21.7 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain DUF815 PF05673.13 ORY53901.1 - 7.7e-05 22.0 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 ORY53901.1 - 0.00015 21.6 0.1 0.0005 19.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 ORY53901.1 - 0.00031 21.0 0.2 0.23 11.7 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_7 PF12775.7 ORY53901.1 - 0.00032 20.3 0.1 0.00073 19.1 0.0 1.6 2 0 0 2 2 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 ORY53901.1 - 0.00047 20.6 0.0 0.0027 18.1 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 ORY53901.1 - 0.00055 19.7 0.0 0.00098 18.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 ORY53901.1 - 0.0016 18.5 0.0 0.086 12.8 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 ORY53901.1 - 0.0027 17.5 0.0 0.0048 16.7 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 ORY53901.1 - 0.0027 18.0 0.3 0.54 10.6 0.0 2.9 1 1 2 3 3 3 1 AAA domain ATPase_2 PF01637.18 ORY53901.1 - 0.003 17.5 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea DEAD PF00270.29 ORY53901.1 - 0.0035 17.1 0.2 0.043 13.6 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_30 PF13604.6 ORY53901.1 - 0.0036 17.1 0.0 0.011 15.5 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 ORY53901.1 - 0.0054 16.7 0.1 0.021 14.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 ORY53901.1 - 0.0084 15.8 0.0 0.023 14.4 0.0 1.5 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 ORY53901.1 - 0.012 15.5 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 ORY53901.1 - 0.021 14.2 0.1 0.12 11.7 0.0 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 ORY53901.1 - 0.024 15.2 0.0 0.05 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 ORY53901.1 - 0.029 13.8 0.1 0.48 9.8 0.0 2.2 1 1 1 2 2 2 0 Bacterial TniB protein DNA_pol3_delta PF06144.13 ORY53901.1 - 0.029 14.2 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit TIP49 PF06068.13 ORY53901.1 - 0.044 13.0 0.0 0.11 11.7 0.0 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_25 PF13481.6 ORY53901.1 - 0.079 12.5 0.1 1.1 8.8 0.0 2.4 2 1 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 ORY53901.1 - 0.1 13.0 0.0 0.21 12.0 0.0 1.7 1 1 0 1 1 1 0 RNA helicase DUF4106 PF13388.6 ORY53901.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) AAA_23 PF13476.6 ORY53901.1 - 0.23 12.0 1.3 0.66 10.4 0.1 2.2 1 1 1 2 2 2 0 AAA domain Gluconate_2-dh3 PF13618.6 ORY53902.1 - 0.16 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 SHMT PF00464.19 ORY53903.1 - 3.4e-203 674.6 0.0 4.2e-203 674.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Microvir_H PF04687.12 ORY53903.1 - 0.031 13.7 0.1 0.045 13.1 0.1 1.2 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) Pkinase PF00069.25 ORY53904.1 - 7.9e-63 212.3 0.0 1e-62 211.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY53904.1 - 9.5e-34 116.8 0.0 1.3e-33 116.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY53904.1 - 2.2e-09 37.1 0.0 3.5e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY53904.1 - 0.00055 19.3 0.2 0.00093 18.6 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 ORY53904.1 - 0.0052 15.8 0.2 0.011 14.7 0.2 1.5 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 ORY53904.1 - 0.096 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 ORY53904.1 - 0.64 8.9 4.5 0.073 12.0 0.2 1.6 2 0 0 2 2 2 0 Haspin like kinase domain cNMP_binding PF00027.29 ORY53905.1 - 2.5e-33 114.0 0.1 8.5e-20 70.6 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 ORY53905.1 - 0.24 11.2 0.4 8.3 6.2 0.1 2.2 2 0 0 2 2 2 0 Cupin domain cNMP_binding PF00027.29 ORY53906.1 - 2.3e-18 66.1 0.2 1.3e-16 60.5 0.1 2.8 3 0 0 3 3 3 1 Cyclic nucleotide-binding domain DUF2441 PF10386.9 ORY53906.1 - 0.053 13.5 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2441) Pkinase PF00069.25 ORY53907.1 - 1.4e-33 116.4 0.7 1.7e-33 116.1 0.7 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY53907.1 - 3.1e-20 72.5 0.6 3.8e-20 72.2 0.6 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY53907.1 - 1e-05 25.1 0.0 1.6e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY53907.1 - 2e-05 24.1 0.1 2.6e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY53907.1 - 9e-05 21.6 0.6 0.00012 21.2 0.6 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 ORY53907.1 - 0.0018 18.2 0.1 0.0024 17.9 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 ORY53908.1 - 2.7e-62 210.5 0.1 3.9e-62 210.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY53908.1 - 1.7e-33 116.0 0.0 2.2e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY53908.1 - 6.6e-10 38.8 0.0 8.7e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 ORY53908.1 - 0.0005 19.5 0.0 0.00087 18.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 ORY53908.1 - 0.0062 15.5 0.2 0.009 15.0 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 ORY53908.1 - 0.014 14.2 0.1 0.15 10.8 0.0 2.0 1 1 1 2 2 2 0 Fungal protein kinase APH PF01636.23 ORY53908.1 - 0.017 15.1 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 ORY53908.1 - 0.02 14.5 0.1 1.1 8.8 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SPC12 PF06645.13 ORY53909.1 - 1.9e-28 98.3 0.7 2.5e-28 97.9 0.7 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MerC PF03203.14 ORY53909.1 - 0.034 14.6 0.1 0.035 14.6 0.1 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein DUF3040 PF11239.8 ORY53909.1 - 0.046 14.0 1.7 0.063 13.6 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) CRPA PF05745.11 ORY53909.1 - 1.6 8.7 6.6 3 7.8 6.6 1.5 1 1 0 1 1 1 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Pkinase PF00069.25 ORY53910.1 - 6e-65 219.2 0.0 7.5e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY53910.1 - 1.7e-37 129.1 0.0 2.1e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY53910.1 - 1.1e-07 31.5 0.0 1.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 ORY53910.1 - 0.00014 20.8 0.0 0.00021 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY53910.1 - 0.00041 19.4 0.5 0.00056 19.0 0.5 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY53910.1 - 0.00044 19.7 0.2 0.00086 18.7 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY53910.1 - 0.00054 20.0 0.3 0.00084 19.3 0.3 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 ORY53910.1 - 0.0082 15.8 0.3 0.21 11.2 0.2 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 ORY53911.1 - 2.5e-62 210.7 0.3 2.9e-62 210.4 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 ORY53911.1 - 4.4e-34 117.9 0.1 5.7e-34 117.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 ORY53911.1 - 7.3e-08 32.1 0.0 1.4e-07 31.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 ORY53911.1 - 0.00013 20.9 0.0 0.00022 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 ORY53911.1 - 0.00043 19.3 0.2 0.00062 18.8 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 ORY53911.1 - 0.0022 17.4 0.1 0.0032 16.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 ORY53911.1 - 0.023 14.6 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 ORY53911.1 - 0.025 13.6 0.1 0.041 12.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Mg_trans_NIPA PF05653.14 ORY53913.1 - 7.1e-90 301.1 14.6 8.5e-90 300.8 14.6 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 ORY53913.1 - 1.1e-06 28.9 32.0 1.6e-06 28.4 6.0 3.4 3 1 0 3 3 3 3 EamA-like transporter family F-box_4 PF15966.5 ORY53914.1 - 0.00042 20.2 0.1 0.81 9.6 0.0 2.6 2 0 0 2 2 2 2 F-box DUF2783 PF10932.8 ORY53914.1 - 5.4 6.8 5.4 8.8 6.1 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2783) F-box_4 PF15966.5 ORY53915.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 F-box NAM-associated PF14303.6 ORY53916.1 - 0.012 16.4 1.5 0.012 16.4 1.5 1.7 1 1 1 2 2 2 0 No apical meristem-associated C-terminal domain HIGH_NTase1 PF05636.11 ORY53916.1 - 0.018 14.3 1.2 0.026 13.8 1.2 1.1 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase 7tm_1 PF00001.21 ORY53917.1 - 1.3e-10 41.1 0.3 1.9e-10 40.5 0.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 ORY53917.1 - 6.2e-06 25.7 17.2 8.7e-06 25.2 17.2 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 ORY53917.1 - 0.32 10.1 16.6 0.094 11.8 12.6 1.8 2 0 0 2 2 2 0 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 ORY53918.1 - 8.2e-09 35.1 8.1 1.2e-08 34.6 8.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 ORY53918.1 - 5.7e-08 32.4 6.1 9.7e-08 31.6 6.1 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.11 ORY53918.1 - 4.2e-05 22.8 12.8 4.2e-05 22.8 12.8 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor Git3 PF11710.8 ORY53918.1 - 0.0002 21.2 11.3 0.0002 21.2 11.3 1.8 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_2 PF00002.24 ORY53919.1 - 1.5e-07 30.9 14.7 2.5e-07 30.3 14.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 ORY53919.1 - 8.2e-06 25.2 17.4 8.8e-06 25.1 12.3 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor TMEM51 PF15345.6 ORY53920.1 - 0.012 15.4 0.2 0.013 15.3 0.2 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 TMEM132D_C PF15706.5 ORY53920.1 - 0.033 14.0 0.1 0.036 13.8 0.1 1.2 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term NicO PF03824.16 ORY53920.1 - 0.083 12.2 0.1 0.083 12.2 0.1 1.0 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF792 PF05632.11 ORY53921.1 - 0.028 14.3 0.1 0.059 13.2 0.1 1.6 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF792) FUSC-like PF12805.7 ORY53922.1 - 0.0049 16.0 1.8 0.0077 15.3 1.8 1.3 1 0 0 1 1 1 1 FUSC-like inner membrane protein yccS Polysacc_synt_C PF14667.6 ORY53922.1 - 0.03 14.4 1.5 0.03 14.4 1.5 2.3 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Cytochrom_B561 PF03188.16 ORY53923.1 - 1.1e-06 28.8 4.2 2.1e-06 27.9 4.2 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 ORY53923.1 - 0.29 10.9 7.7 3 7.7 3.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF2427) DUF2427 PF10348.9 ORY53924.1 - 1.3e-05 25.0 1.1 0.12 12.2 0.0 2.8 2 1 1 3 3 3 2 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 ORY53924.1 - 0.00018 21.7 7.2 0.0003 20.9 0.6 2.7 1 1 2 3 3 3 2 Eukaryotic cytochrome b561 Helicase_C PF00271.31 ORY53926.1 - 8.7e-15 55.0 0.1 1.9e-14 54.0 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 ORY53926.1 - 7.6e-12 45.5 0.0 1.6e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 ORY53926.1 - 1.7e-10 40.9 0.0 4.2e-10 39.7 0.0 1.7 2 0 0 2 2 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 ORY53926.1 - 2e-08 34.5 0.0 9.3e-08 32.3 0.0 2.2 2 1 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 ORY53926.1 - 0.00023 21.5 0.2 0.0009 19.5 0.2 1.9 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 ORY53926.1 - 0.004 16.5 0.0 0.0083 15.5 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_23 PF13476.6 ORY53926.1 - 0.0046 17.5 0.1 0.012 16.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 ORY53926.1 - 0.0049 17.2 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 ORY53926.1 - 0.042 14.4 0.0 0.088 13.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.12 ORY53926.1 - 0.068 13.1 0.0 0.24 11.3 0.0 2.0 1 1 0 1 1 1 0 NACHT domain Rad17 PF03215.15 ORY53926.1 - 0.11 12.4 0.4 0.37 10.7 0.0 2.0 3 0 0 3 3 2 0 Rad17 P-loop domain AAA_30 PF13604.6 ORY53926.1 - 0.12 12.1 0.1 0.55 9.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF3602 PF12223.8 ORY53926.1 - 0.12 13.0 0.0 0.29 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3602) PhoH PF02562.16 ORY53926.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 ORY53926.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein RsgA_GTPase PF03193.16 ORY53926.1 - 0.14 12.1 0.2 0.57 10.1 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase TIR_2 PF13676.6 ORY53928.1 - 2.4e-16 60.4 0.0 8.6e-16 58.6 0.0 1.9 2 0 0 2 2 2 1 TIR domain NACHT PF05729.12 ORY53928.1 - 4e-08 33.4 0.1 4.7e-06 26.6 0.1 2.4 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 ORY53928.1 - 0.031 14.7 0.1 0.18 12.2 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 ORY53928.1 - 0.082 12.6 0.0 5.4 6.7 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 ORY53928.1 - 0.092 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain OrsD PF12013.8 ORY53930.1 - 0.0092 16.4 5.3 0.12 12.8 2.6 2.8 1 1 1 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-H2C2_5 PF13909.6 ORY53930.1 - 0.14 11.9 9.6 2.2 8.1 3.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 ORY53930.1 - 5.6 8.1 10.2 11 7.2 0.2 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 ORY53931.1 - 0.0012 19.2 11.0 3 8.5 2.0 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type OrsD PF12013.8 ORY53931.1 - 0.089 13.2 8.5 0.33 11.4 2.0 2.9 2 1 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf_C2H2_ZHX PF18387.1 ORY53931.1 - 0.43 10.2 8.3 1.7 8.4 1.3 2.5 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_4 PF13894.6 ORY53931.1 - 3.4 8.8 16.7 7.1 7.8 2.4 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Rhizoclosmatium_globosum_JEL800-Rhihy1/GCA_002104985.1_Rhihy1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Rhizoclosmatium_globosum_JEL800-Rhihy1/GCA_002104985.1_Rhihy1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Rhizoclosmatium_globosum_JEL800-Rhihy1/GCA_002104985.1_Rhihy1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Rhizoclosmatium_globosum_JEL800-Rhihy1/GCA_002104985.1_Rhihy1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 05:45:56 2019 # [ok]