# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Pec_lyase_C PF00544.14 KFX85682.1 - 9.2e-36 123.1 2.9 1.5e-35 122.4 2.0 1.3 1 0 0 1 1 1 1 Pectate lyase Dicty_CAR PF05462.6 KFX85683.1 - 6.4e-08 31.8 2.3 6.4e-08 31.8 1.6 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 KFX85683.1 - 8.4e-07 28.7 4.8 1.4e-06 28.0 2.7 1.8 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 KFX85683.1 - 1.4e-06 27.6 0.0 2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Sru PF10322.4 KFX85683.1 - 0.14 11.1 4.6 0.25 10.4 3.2 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru DUF4064 PF13273.1 KFX85683.1 - 0.15 12.1 3.3 9.5 6.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) PIG-P PF08510.7 KFX85683.1 - 1.2 8.7 4.1 4.3 6.9 0.7 2.7 2 1 0 2 2 2 0 PIG-P DUF4064 PF13273.1 KFX85684.1 - 0.33 11.0 12.4 2.1 8.5 1.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Cu-oxidase_3 PF07732.10 KFX85685.1 - 3.6e-37 126.6 0.5 2.3e-36 124.0 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFX85685.1 - 1.8e-25 89.0 2.3 3.4e-19 68.7 0.1 4.4 4 1 1 5 5 5 3 Multicopper oxidase Cu-oxidase PF00394.17 KFX85685.1 - 4.9e-13 49.2 0.0 1.2e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase Methyltransf_12 PF08242.7 KFX85686.1 - 1.7e-14 54.0 0.0 4e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX85686.1 - 1.2e-11 44.6 0.0 1.1e-09 38.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX85686.1 - 1.9e-06 28.2 0.0 3.7e-05 24.1 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX85686.1 - 4e-06 27.1 0.0 8.7e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KFX85686.1 - 2.5e-05 24.4 0.0 5.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_26 PF13659.1 KFX85686.1 - 7.3e-05 22.7 0.0 0.00031 20.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX85686.1 - 0.00016 22.2 0.0 0.00051 20.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX85686.1 - 0.00029 20.4 0.0 0.00056 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX85686.1 - 0.052 12.6 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CUE PF02845.11 KFX85696.1 - 8e-12 44.4 0.0 1.2e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 CUE domain UBA PF00627.26 KFX85696.1 - 9.6e-05 22.1 0.0 0.00016 21.4 0.0 1.3 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 KFX85696.1 - 0.031 13.8 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain FXR1P_C PF12235.3 KFX85696.1 - 3.3 7.7 20.5 0.087 12.9 3.9 2.4 2 0 0 2 2 2 0 Fragile X-related 1 protein C terminal AT_hook PF02178.14 KFX85699.1 - 0.033 13.8 2.8 0.11 12.2 1.9 2.0 1 0 0 1 1 1 0 AT hook motif zf-C2H2 PF00096.21 KFX85708.1 - 7.2e-10 38.6 17.1 0.0017 18.5 0.6 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX85708.1 - 7.5e-08 32.1 13.3 0.052 13.8 1.2 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 KFX85708.1 - 0.001 19.1 10.0 0.26 11.5 0.0 4.4 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFX85708.1 - 0.062 13.4 11.7 5.9 7.1 0.7 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding GATA PF00320.22 KFX85708.1 - 0.79 9.1 4.2 3.4 7.0 0.1 2.5 2 0 0 2 2 2 0 GATA zinc finger zinc_ribbon_2 PF13240.1 KFX85708.1 - 2.5 7.6 6.0 1.9 8.0 0.7 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 KFX85708.1 - 3 8.3 11.5 1.2 9.5 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_2 PF12756.2 KFX85708.1 - 4.6 7.4 10.1 14 5.9 0.1 3.6 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 KFX85708.1 - 8.5 6.4 10.7 12 5.9 0.2 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Di19 PF05605.7 KFX85708.1 - 8.6 6.5 8.6 28 4.9 0.3 3.4 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding KilA-N PF04383.8 KFX85715.1 - 0.004 16.7 0.0 0.019 14.5 0.0 2.1 1 1 0 1 1 1 1 KilA-N domain IER PF05760.7 KFX85715.1 - 0.006 16.5 18.2 0.009 15.9 12.6 1.2 1 0 0 1 1 1 1 Immediate early response protein (IER) NAD_binding_2 PF03446.10 KFX85716.1 - 1.8e-37 128.6 0.6 2.6e-37 128.1 0.4 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KFX85716.1 - 2.7e-32 111.4 0.0 4.4e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KFX85716.1 - 1.6e-07 31.6 0.2 9.3e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 KFX85716.1 - 0.03 14.8 0.1 0.064 13.7 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_Gly3P_dh_N PF01210.18 KFX85716.1 - 0.047 13.4 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Mito_carr PF00153.22 KFX85724.1 - 2.9e-16 58.9 4.7 4.4e-06 26.3 0.8 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Copper-bind PF00127.15 KFX85725.1 - 0.0014 18.8 0.2 0.0072 16.5 0.1 2.0 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cytochrom_B561 PF03188.11 KFX85726.1 - 1.9e-05 24.4 11.9 4.3e-05 23.3 5.9 1.7 1 1 1 2 2 2 2 Eukaryotic cytochrome b561 DUF2427 PF10348.4 KFX85726.1 - 8.4e-05 22.1 5.9 0.029 13.9 0.7 3.5 3 1 1 4 4 4 2 Domain of unknown function (DUF2427) DUF2306 PF10067.4 KFX85726.1 - 0.021 14.9 1.0 0.021 14.9 0.7 3.0 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) PTPLA PF04387.9 KFX85726.1 - 0.06 12.7 0.1 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase-like protein, PTPLA DUF2231 PF09990.4 KFX85726.1 - 8.1 6.8 8.0 8.1 6.8 2.8 2.4 1 1 2 3 3 3 0 Predicted membrane protein (DUF2231) PI3_PI4_kinase PF00454.22 KFX85733.1 - 4e-32 111.5 0.0 6.8e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase MFS_1 PF07690.11 KFX85740.1 - 5.3e-21 74.7 50.4 1.1e-18 67.1 24.5 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily ATG22 PF11700.3 KFX85740.1 - 0.57 8.5 24.5 0.078 11.4 7.2 2.2 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like DUF2422 PF10337.4 KFX85752.1 - 5.5e-97 325.4 5.8 2.4e-96 323.3 3.1 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 KFX85752.1 - 1.1e-15 57.6 19.0 1.1e-15 57.6 13.2 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 KFX85752.1 - 3.4e-05 23.5 0.0 0.00059 19.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) ALMT PF11744.3 KFX85752.1 - 0.038 12.6 7.2 0.072 11.7 4.0 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter DCP2 PF05026.8 KFX85758.1 - 2e-36 123.7 0.8 4.1e-36 122.7 0.6 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 KFX85758.1 - 5.6e-17 61.6 0.0 1.2e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Lipoprotein_10 PF03202.8 KFX85758.1 - 0.21 11.6 2.9 0.15 12.0 0.7 1.7 2 0 0 2 2 2 0 Putative mycoplasma lipoprotein, C-terminal region DUF4112 PF13430.1 KFX85759.1 - 1.7e-34 117.9 0.2 2.4e-34 117.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) UPF0020 PF01170.13 KFX85763.1 - 9.9e-11 41.5 0.0 1.6e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 KFX85763.1 - 1.7e-08 34.5 0.1 3.1e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Hexokinase_1 PF00349.16 KFX85770.1 - 9.8e-67 224.2 0.1 1.5e-66 223.6 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 KFX85770.1 - 6.4e-47 159.8 0.0 9e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Abhydrolase_6 PF12697.2 KFX85777.1 - 2.2e-18 66.9 2.4 2.2e-18 66.9 1.6 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFX85777.1 - 2.2e-17 62.6 1.0 6.5e-17 61.1 0.0 2.2 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 KFX85777.1 - 2.8e-14 53.1 0.0 5.9e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family GCD14 PF08704.5 KFX85777.1 - 0.00032 20.2 0.0 0.0078 15.7 0.0 2.3 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Abhydrolase_1 PF00561.15 KFX85777.1 - 0.0026 17.3 0.0 0.01 15.4 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Methyltransf_31 PF13847.1 KFX85777.1 - 0.0034 16.9 0.0 0.15 11.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Peptidase_S9 PF00326.16 KFX85777.1 - 0.0082 15.3 0.3 0.041 13.1 0.0 2.2 2 1 1 3 3 3 1 Prolyl oligopeptidase family Lipase_3 PF01764.20 KFX85777.1 - 0.018 14.6 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Methyltransf_24 PF13578.1 KFX85777.1 - 0.066 14.0 1.2 0.76 10.6 0.0 3.1 4 0 0 4 4 3 0 Methyltransferase domain Chlorophyllase2 PF12740.2 KFX85777.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.8 KFX85777.1 - 0.16 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein AXE1 PF05448.7 KFX85777.1 - 0.21 10.0 0.0 0.98 7.8 0.0 1.9 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) ArsA_ATPase PF02374.10 KFX85784.1 - 6.7e-115 383.3 0.0 7.6e-115 383.1 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 KFX85784.1 - 1.4e-16 60.5 0.2 2.4e-16 59.7 0.1 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KFX85784.1 - 1.5e-08 34.7 0.0 6.6e-08 32.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 KFX85784.1 - 4.9e-06 25.9 0.0 8.6e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 KFX85784.1 - 6.1e-05 22.5 0.1 0.0023 17.3 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 KFX85784.1 - 0.00068 19.0 0.0 0.0024 17.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFX85784.1 - 0.0061 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KFX85784.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein YhjQ PF06564.7 KFX85784.1 - 0.028 13.7 0.0 0.065 12.5 0.0 1.5 1 0 0 1 1 1 0 YhjQ protein MipZ PF09140.6 KFX85784.1 - 0.029 13.4 0.0 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 ATPase MipZ NB-ARC PF00931.17 KFX85784.1 - 0.1 11.4 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 KFX85784.1 - 0.16 12.2 0.1 0.43 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATE_C PF04377.10 KFX85788.1 - 9.1e-41 138.9 1.3 9.9e-41 138.7 0.2 1.6 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 KFX85788.1 - 3.4e-19 68.4 2.9 6.2e-19 67.5 1.4 2.0 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.1 KFX85788.1 - 0.0019 18.1 0.2 0.006 16.5 0.2 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain UPF0113 PF03657.8 KFX85793.1 - 1.1e-06 28.3 0.0 1.9e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 KFX85793.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 PUA domain NOC3p PF07540.6 KFX85794.1 - 4e-33 113.5 0.3 1.5e-32 111.7 0.2 2.1 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.12 KFX85794.1 - 3.3e-24 85.1 0.0 8e-24 83.9 0.0 1.7 1 0 0 1 1 1 1 CBF/Mak21 family Trypan_PARP PF05887.6 KFX85794.1 - 0.028 14.2 10.2 0.081 12.7 7.1 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Patatin PF01734.17 KFX85797.1 - 1.2e-13 51.4 0.1 3.1e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase Fungal_trans PF04082.13 KFX85807.1 - 0.0068 15.3 0.0 0.013 14.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 KFX85808.1 - 1.2e-28 100.1 0.2 1.8e-27 96.3 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFX85808.1 - 4.4e-08 32.4 0.9 0.0008 18.4 0.8 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KFX85808.1 - 2.3e-06 26.9 0.6 0.018 14.1 0.1 2.4 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KFX85808.1 - 1.8e-05 24.9 0.0 4.1e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX85808.1 - 4e-05 23.5 1.1 0.00012 21.9 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KFX85808.1 - 8.9e-05 21.5 0.4 0.04 12.8 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.12 KFX85808.1 - 0.00034 19.7 0.4 0.0012 18.0 0.1 1.8 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KFX85808.1 - 0.00057 18.4 0.4 0.029 12.8 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 KFX85808.1 - 0.0018 18.6 1.8 0.017 15.4 0.6 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KFX85808.1 - 0.0045 16.7 0.3 0.015 15.1 0.1 1.9 2 0 0 2 2 2 1 ThiF family Pyr_redox_2 PF07992.9 KFX85808.1 - 0.0089 15.9 0.6 0.018 14.9 0.4 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KFX85808.1 - 0.011 15.3 0.2 0.023 14.2 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 KFX85808.1 - 0.018 13.9 1.0 0.028 13.2 0.7 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 KFX85808.1 - 0.018 13.6 0.0 0.028 13.0 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.13 KFX85808.1 - 0.048 13.6 0.1 0.12 12.3 0.0 1.7 2 0 0 2 2 1 0 TrkA-N domain NAD_binding_9 PF13454.1 KFX85808.1 - 0.053 13.2 1.2 5.7 6.6 0.1 3.2 3 0 0 3 3 3 0 FAD-NAD(P)-binding ApbA PF02558.11 KFX85808.1 - 0.1 12.0 0.3 0.19 11.1 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 KFX85808.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding His_Phos_2 PF00328.17 KFX85812.1 - 8.7e-47 160.1 0.0 1.2e-46 159.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KFX85812.1 - 7.7e-06 25.5 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Glyco_hydro_18 PF00704.23 KFX85815.1 - 0.0015 18.0 0.0 0.0021 17.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Mcp5_PH PF12814.2 KFX85819.1 - 2.9e-49 166.0 0.0 7.1e-49 164.8 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.7 KFX85819.1 - 0.34 10.6 10.0 2.2 8.0 7.0 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 KFX85819.1 - 0.41 10.2 5.9 0.89 9.1 4.1 1.5 1 0 0 1 1 1 0 IncA protein GAS PF13851.1 KFX85819.1 - 1.4 8.0 6.0 2.4 7.2 4.1 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF724 PF05266.9 KFX85819.1 - 2.8 7.5 7.0 0.7 9.4 2.1 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF724) CCDC-167 PF15188.1 KFX85819.1 - 4.5 7.2 7.3 4 7.4 1.6 2.5 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 WD40 PF00400.27 KFX85820.1 - 2e-08 33.8 0.1 7.1e-06 25.7 0.0 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat Aminotran_5 PF00266.14 KFX85821.1 - 5.7e-27 94.4 0.0 7.4e-27 94.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KFX85821.1 - 0.00084 18.3 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II B12-binding PF02310.14 KFX85821.1 - 0.0019 18.0 0.1 0.0078 16.0 0.0 2.1 2 1 0 2 2 2 1 B12 binding domain adh_short PF00106.20 KFX85821.1 - 0.039 13.8 0.0 0.087 12.7 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 KFX85821.1 - 0.048 13.3 0.1 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 KR domain Fungal_trans PF04082.13 KFX85825.1 - 1.8e-33 115.5 1.3 2.8e-33 114.9 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX85825.1 - 1.8e-06 27.7 6.4 3.8e-06 26.7 4.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_2 PF12756.2 KFX85827.1 - 2.7e-32 110.8 8.0 1.6e-26 92.3 0.4 3.6 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFX85827.1 - 0.0052 16.9 1.5 0.0052 16.9 1.0 3.4 4 0 0 4 4 4 1 Zinc-finger of C2H2 type AKAP95 PF04988.7 KFX85827.1 - 0.018 14.8 0.3 0.018 14.8 0.2 3.2 2 2 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_jaz PF12171.3 KFX85827.1 - 0.022 14.8 0.0 0.022 14.8 0.0 4.1 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFX85827.1 - 0.4 10.6 0.1 0.4 10.6 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger X8 PF07983.8 KFX85832.1 - 5.1e-21 74.9 1.5 7.8e-21 74.3 1.1 1.3 1 0 0 1 1 1 1 X8 domain Spore_YtfJ PF09579.5 KFX85832.1 - 0.62 9.9 2.9 1.1 9.1 2.0 1.5 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) EF-1_beta_acid PF10587.4 KFX85841.1 - 1.2 9.2 5.5 1.9 8.6 0.2 3.0 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region CTP_transf_2 PF01467.21 KFX85845.1 - 0.025 14.6 1.4 0.33 10.9 0.6 2.7 2 1 0 2 2 2 0 Cytidylyltransferase Pkinase PF00069.20 KFX85849.1 - 1.6e-27 96.3 0.0 2.3e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX85849.1 - 2.6e-16 59.4 0.0 4.5e-16 58.7 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase F-box-like PF12937.2 KFX85849.1 - 0.011 15.3 1.7 0.044 13.4 0.3 2.2 2 0 0 2 2 2 0 F-box-like CTP_transf_2 PF01467.21 KFX85860.1 - 0.058 13.4 0.0 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 Cytidylyltransferase MFS_1 PF07690.11 KFX85861.1 - 8.6e-24 83.8 20.7 1e-23 83.6 14.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KFX85861.1 - 0.009 14.2 2.4 0.01 14.0 1.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3720 PF12517.3 KFX85861.1 - 0.19 12.4 2.7 0.25 12.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) DUF3464 PF11947.3 KFX85861.1 - 0.69 9.3 2.4 5.5 6.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3464) Adeno_E3_CR2 PF02439.10 KFX85861.1 - 2 8.0 4.4 5.6 6.6 3.0 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 zf-His_Me_endon PF05551.6 KFX85863.1 - 3.1e-12 46.5 2.6 3.1e-12 46.5 1.8 2.4 2 1 0 2 2 2 1 Zinc-binding loop region of homing endonuclease Asp-B-Hydro_N PF05279.6 KFX85866.1 - 2.8 7.7 10.7 3.3 7.4 7.4 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Sugar_tr PF00083.19 KFX85869.1 - 7.4e-106 354.4 25.3 9.1e-106 354.1 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX85869.1 - 1.7e-23 82.9 37.9 4e-20 71.8 5.0 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFX85869.1 - 6.7e-05 21.2 0.8 6.7e-05 21.2 0.5 2.3 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) AAA PF00004.24 KFX85881.1 - 5.6e-38 130.1 0.0 1.4e-37 128.8 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KFX85881.1 - 7.6e-06 25.8 0.0 1.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFX85881.1 - 1.1e-05 25.5 0.9 0.00035 20.6 0.1 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KFX85881.1 - 1.2e-05 25.4 0.1 0.00054 20.1 0.1 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KFX85881.1 - 2.4e-05 23.5 0.0 3.9e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KFX85881.1 - 2.5e-05 25.0 0.0 6.6e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFX85881.1 - 4e-05 23.3 0.2 0.00043 20.0 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KFX85881.1 - 4.7e-05 23.3 0.0 0.00011 22.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 KFX85881.1 - 0.00016 21.1 0.6 0.033 13.5 0.0 3.2 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 KFX85881.1 - 0.00017 21.0 0.2 0.00041 19.8 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 KFX85881.1 - 0.00034 20.4 0.0 0.00078 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 KFX85881.1 - 0.00064 19.7 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 KFX85881.1 - 0.00081 18.6 0.1 0.0017 17.5 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KFX85881.1 - 0.0017 18.5 0.0 0.0043 17.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 KFX85881.1 - 0.0024 17.0 0.1 0.0064 15.6 0.0 1.7 2 0 0 2 2 1 1 Zeta toxin NACHT PF05729.7 KFX85881.1 - 0.0024 17.5 0.0 0.01 15.5 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 KFX85881.1 - 0.003 17.5 0.0 0.0075 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFX85881.1 - 0.0048 16.6 0.1 0.025 14.3 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_24 PF13479.1 KFX85881.1 - 0.0068 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFX85881.1 - 0.0083 16.4 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 KFX85881.1 - 0.015 14.8 0.0 0.035 13.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 KFX85881.1 - 0.019 15.2 0.0 0.045 14.0 0.0 1.8 1 1 0 1 1 1 0 ABC transporter CPT PF07931.7 KFX85881.1 - 0.019 14.6 1.5 0.13 11.8 0.0 2.7 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein Parvo_NS1 PF01057.12 KFX85881.1 - 0.021 13.6 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 KFX85881.1 - 0.022 13.6 0.0 0.19 10.5 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Guanylate_kin PF00625.16 KFX85881.1 - 0.032 13.6 0.0 0.84 9.0 0.0 2.8 3 1 0 3 3 3 0 Guanylate kinase TIP49 PF06068.8 KFX85881.1 - 0.034 12.8 0.1 0.31 9.7 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus Rad17 PF03215.10 KFX85881.1 - 0.042 12.5 0.0 0.093 11.3 0.0 1.5 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DUF815 PF05673.8 KFX85881.1 - 0.064 12.1 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_10 PF12846.2 KFX85881.1 - 0.064 12.6 0.9 1.8 7.9 0.0 3.3 4 1 0 4 4 3 0 AAA-like domain KaiC PF06745.8 KFX85881.1 - 0.082 12.0 0.0 0.66 9.0 0.0 2.1 1 1 1 2 2 2 0 KaiC UPF0079 PF02367.12 KFX85881.1 - 0.084 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 KFX85881.1 - 0.084 12.5 0.0 0.28 10.8 0.0 1.7 1 1 1 2 2 2 0 Archaeal ATPase SKI PF01202.17 KFX85881.1 - 0.11 12.4 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Shikimate kinase Viral_helicase1 PF01443.13 KFX85881.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF641 PF04859.7 KFX85884.1 - 0.071 12.8 2.0 1.1 8.9 0.6 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) zf-Di19 PF05605.7 KFX85884.1 - 0.082 13.0 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding GOLGA2L5 PF15070.1 KFX85884.1 - 0.082 11.3 1.3 0.14 10.6 0.9 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 TMF_DNA_bd PF12329.3 KFX85884.1 - 0.22 11.3 3.0 0.25 11.1 0.8 2.0 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.1 KFX85884.1 - 2.2 8.2 6.1 0.35 10.8 1.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) His_Phos_1 PF00300.17 KFX85885.1 - 3e-09 37.1 0.0 5.6e-09 36.2 0.0 1.4 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 KFX85889.1 - 3.8e-42 144.8 0.0 4.5e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF4628 PF15429.1 KFX85892.1 - 1.9 7.8 5.8 3 7.2 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) DUF2040 PF09745.4 KFX85899.1 - 0.066 13.0 2.1 1.2 8.9 0.3 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) Coiled-coil_56 PF09813.4 KFX85899.1 - 0.096 12.6 2.5 0.12 12.3 0.0 2.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 56 RRP7 PF12923.2 KFX85910.1 - 0.1 12.5 3.9 0.28 11.2 2.7 1.7 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) Neuregulin PF02158.10 KFX85910.1 - 0.28 9.9 2.3 0.29 9.8 1.6 1.0 1 0 0 1 1 1 0 Neuregulin family JCAD PF15351.1 KFX85910.1 - 2.4 5.6 6.2 2.4 5.6 4.3 1.0 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease CENP-B_dimeris PF09026.5 KFX85910.1 - 3.7 7.8 7.3 4.2 7.6 5.0 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BSD PF03909.12 KFX85911.1 - 5.5e-13 48.4 0.0 9.6e-13 47.6 0.0 1.4 1 0 0 1 1 1 1 BSD domain COPI_C PF06957.6 KFX85911.1 - 0.045 12.2 0.8 0.091 11.2 0.6 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Trs65 PF12735.2 KFX85914.1 - 1.6e-29 103.1 0.0 1.8e-29 103.0 0.0 1.0 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Fungal_trans PF04082.13 KFX85915.1 - 1.5e-20 73.1 0.0 3e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF605 PF04652.11 KFX85915.1 - 0.024 14.0 37.8 0.044 13.1 26.2 1.4 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 KFX85915.1 - 0.64 8.1 53.2 0.93 7.6 36.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 KFX85915.1 - 2.6 7.7 18.1 5.3 6.6 12.5 1.5 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Abi PF02517.11 KFX85919.1 - 0.41 10.8 3.5 0.68 10.1 2.5 1.3 1 0 0 1 1 1 0 CAAX protease self-immunity DUF2892 PF11127.3 KFX85919.1 - 5.9 6.7 7.8 0.26 11.1 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) LRR_6 PF13516.1 KFX85922.1 - 6.1e-11 41.2 5.0 0.23 11.6 0.0 6.7 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.2 KFX85922.1 - 1.3e-06 27.9 9.9 0.24 11.0 0.2 5.6 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFX85922.1 - 0.0026 17.5 5.4 7.2 7.0 0.0 5.6 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_8 PF13855.1 KFX85922.1 - 0.73 9.6 9.1 26 4.6 0.0 4.1 4 2 0 4 4 4 0 Leucine rich repeat LRR_7 PF13504.1 KFX85922.1 - 6.6 7.4 7.1 44 4.9 0.0 4.4 5 0 0 5 5 5 0 Leucine rich repeat COX17 PF05051.8 KFX85923.1 - 2.1e-20 72.4 4.8 2.4e-20 72.3 3.3 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 KFX85923.1 - 0.21 11.3 4.1 0.65 9.8 0.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like zf-C2H2 PF00096.21 KFX85925.1 - 2.9e-27 93.3 46.5 0.00051 20.2 0.2 10.8 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX85925.1 - 5.9e-23 79.4 49.4 0.012 15.8 0.2 11.0 9 1 1 10 10 10 10 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFX85925.1 - 9.1e-07 28.8 62.4 0.00011 22.2 0.1 10.6 12 1 0 12 12 12 5 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFX85925.1 - 1.2e-06 28.4 31.4 0.16 12.1 0.5 8.4 9 0 0 9 9 9 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFX85925.1 - 0.00011 22.2 21.9 2.1 8.6 0.0 8.4 8 0 0 8 8 8 2 Zinc-finger of C2H2 type DUF4187 PF13821.1 KFX85925.1 - 0.0045 16.5 0.5 0.022 14.3 0.4 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-H2C2_5 PF13909.1 KFX85925.1 - 0.91 9.8 0.0 0.1 12.8 0.7 8.1 8 1 0 8 8 8 0 C2H2-type zinc-finger domain RNA_pol_Rpb6 PF01192.17 KFX85926.1 - 1.5e-24 85.4 0.3 2.2e-24 84.9 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Ank_2 PF12796.2 KFX85932.1 - 7e-53 176.9 7.8 2.6e-20 72.5 0.6 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFX85932.1 - 5.7e-40 133.1 9.6 1.8e-05 24.2 0.0 7.1 7 0 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.1 KFX85932.1 - 8.7e-34 112.1 0.9 0.00029 20.7 0.0 7.1 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 KFX85932.1 - 2.8e-28 97.7 0.1 2.9e-09 37.1 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX85932.1 - 5.7e-26 89.9 7.4 0.0001 22.4 0.0 7.0 1 1 5 7 7 7 7 Ankyrin repeats (many copies) Ribophorin_I PF04597.9 KFX85937.1 - 1.2e-73 248.1 0.9 1.3e-73 247.9 0.6 1.0 1 0 0 1 1 1 1 Ribophorin I Lipoprotein_17 PF04200.7 KFX85937.1 - 0.44 10.7 3.5 1.3 9.2 2.4 1.8 1 1 1 2 2 2 0 Lipoprotein associated domain Nucleos_tra2_C PF07662.8 KFX85941.1 - 1.1e-63 214.5 1.7 1.2e-63 214.3 1.2 1.0 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus ATP1G1_PLM_MAT8 PF02038.11 KFX85941.1 - 0.21 10.6 1.1 0.47 9.4 0.8 1.6 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF2569 PF10754.4 KFX85941.1 - 0.48 10.6 3.7 1.2 9.2 2.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) Ion_trans_2 PF07885.11 KFX85943.1 - 4.3e-31 106.4 26.4 1e-17 63.5 3.6 3.3 3 0 0 3 3 3 2 Ion channel Tnp_P_element_C PF12596.3 KFX85947.1 - 0.11 12.8 0.0 0.3 11.4 0.0 1.7 2 0 0 2 2 2 0 87kDa Transposase Gryzun PF07919.7 KFX85953.1 - 9.8e-77 258.5 0.2 1.2e-76 258.2 0.1 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.2 KFX85953.1 - 0.00059 19.6 0.3 0.0021 17.8 0.0 2.0 2 0 0 2 2 2 1 Gryzun, putative Golgi trafficking Abhydrolase_6 PF12697.2 KFX85954.1 - 7e-19 68.6 0.2 9.8e-19 68.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX85954.1 - 0.00083 18.9 0.0 0.033 13.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Thioredoxin_2 PF13098.1 KFX85954.1 - 0.029 14.5 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain DUF1741 PF08427.5 KFX85958.1 - 3.7e-11 42.9 0.8 1e-10 41.5 0.1 2.1 2 1 1 3 3 3 1 Domain of unknown function (DUF1741) Dymeclin PF09742.4 KFX85958.1 - 0.051 11.6 1.0 0.095 10.8 0.7 1.4 1 1 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein ICE2 PF08426.5 KFX85963.1 - 9.3e-67 225.4 8.9 1e-66 225.2 6.1 1.0 1 0 0 1 1 1 1 ICE2 DUF4117 PF13491.1 KFX85963.1 - 7.5 5.9 12.6 2.5 7.5 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4117) UPF0160 PF03690.8 KFX85964.1 - 1.3e-87 294.2 0.0 1.6e-87 293.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Etmic-2 PF06670.6 KFX85964.1 - 0.078 11.6 0.0 0.098 11.3 0.0 1.1 1 0 0 1 1 1 0 Microneme protein Etmic-2 Reticulon PF02453.12 KFX85966.1 - 1.8e-30 105.7 0.8 2.5e-30 105.3 0.6 1.2 1 0 0 1 1 1 1 Reticulon Aminotran_1_2 PF00155.16 KFX85967.1 - 8.4e-44 149.9 0.0 9.3e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 KFX85967.1 - 0.078 11.6 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Allinase Cation_efflux PF01545.16 KFX85971.1 - 2e-76 256.8 7.6 7.2e-76 254.9 5.3 1.7 1 1 0 1 1 1 1 Cation efflux family ADH_N PF08240.7 KFX85976.1 - 4.4e-20 71.4 0.4 3.6e-19 68.5 0.2 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX85976.1 - 3.9e-06 26.4 0.0 7.5e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_oxidored PF12831.2 KFX85976.1 - 0.028 13.4 0.2 0.042 12.9 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFX85976.1 - 0.043 12.6 0.2 0.062 12.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain ADH_N_assoc PF13823.1 KFX85976.1 - 0.059 13.0 0.1 0.059 13.0 0.1 2.1 2 1 0 2 2 2 0 Alcohol dehydrogenase GroES-associated 3HCDH_N PF02737.13 KFX85976.1 - 0.11 12.1 0.7 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PCRF PF03462.13 KFX85977.1 - 2.3e-28 98.2 0.0 4.9e-28 97.1 0.0 1.6 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.15 KFX85977.1 - 3.4e-07 30.0 0.0 6.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 RF-1 domain OTU PF02338.14 KFX85980.1 - 8.1e-11 42.5 0.0 1.4e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KFX85980.1 - 0.00023 20.6 0.3 0.0012 18.2 0.0 1.9 1 1 1 2 2 2 1 Peptidase C65 Otubain Vps39_2 PF10367.4 KFX85991.1 - 4.7e-05 23.5 0.0 6.3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 PseudoU_synth_2 PF00849.17 KFX85993.1 - 1.7e-25 89.7 0.0 2.9e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Ub-Mut7C PF14451.1 KFX85993.1 - 0.0047 16.4 0.1 0.011 15.2 0.1 1.6 1 0 0 1 1 1 1 Mut7-C ubiquitin S4 PF01479.20 KFX85993.1 - 0.14 11.6 1.1 0.28 10.6 0.7 1.5 1 0 0 1 1 1 0 S4 domain HCO3_cotransp PF00955.16 KFX85995.1 - 1.3e-66 225.3 14.5 5.5e-39 134.2 4.2 2.0 1 1 1 2 2 2 2 HCO3- transporter family p450 PF00067.17 KFX85998.1 - 3.9e-10 38.8 0.0 4.6e-10 38.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 KFX85999.1 - 2.6e-20 73.3 0.0 3.6e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX85999.1 - 0.00046 19.8 0.0 0.0033 17.0 0.0 1.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 KFX85999.1 - 0.0017 18.0 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase bPH_6 PF10756.4 KFX85999.1 - 0.017 15.0 0.1 0.048 13.5 0.1 1.7 1 0 0 1 1 1 0 Bacterial PH domain DUF1057 PF06342.7 KFX85999.1 - 0.022 13.5 0.0 1.8 7.2 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) PRP4 PF08799.6 KFX86000.1 - 2e-12 46.1 0.8 4.5e-12 45.0 0.5 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ARS2 PF04959.8 KFX86000.1 - 0.11 12.6 0.2 0.16 12.0 0.2 1.2 1 0 0 1 1 1 0 Arsenite-resistance protein 2 MutS_I PF01624.15 KFX86002.1 - 1e-19 70.6 0.0 1.7e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KFX86002.1 - 1.2e-09 38.3 0.0 1.8e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 MutS domain II FMN_red PF03358.10 KFX86003.1 - 1.5e-10 40.7 0.0 1.8e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 KFX86003.1 - 7.1e-09 35.8 0.0 1.1e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 KFX86003.1 - 7.5e-05 22.3 0.0 9.4e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_4 PF12682.2 KFX86003.1 - 0.13 11.6 0.3 0.64 9.3 0.1 2.1 2 1 0 2 2 2 0 Flavodoxin Zn_clus PF00172.13 KFX86004.1 - 2.7e-08 33.6 10.9 4.4e-08 32.8 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX86004.1 - 0.001 17.9 0.1 0.0016 17.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dsh_C PF12316.3 KFX86006.1 - 0.089 12.8 4.6 0.1 12.6 3.2 1.0 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal DUF3176 PF11374.3 KFX86008.1 - 1.2e-30 105.6 0.4 4.5e-30 103.7 0.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Pkinase PF00069.20 KFX86010.1 - 6.7e-34 117.2 0.7 2.5e-24 85.8 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFX86010.1 - 8.5e-12 44.6 0.4 1.1e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KFX86010.1 - 0.21 10.3 0.1 0.31 9.7 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Rad52_Rad22 PF04098.10 KFX86014.1 - 3.2e-62 208.8 0.0 4.3e-62 208.3 0.0 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein TFIIA PF03153.8 KFX86014.1 - 2.7 7.8 7.8 4.3 7.1 5.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 KFX86014.1 - 3.6 5.7 22.5 4.5 5.3 15.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Fungal_trans PF04082.13 KFX86015.1 - 6e-10 38.4 0.0 1e-09 37.6 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 KFX86017.1 - 5.8e-10 38.9 15.9 9.9e-06 25.5 2.1 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFX86017.1 - 6.5e-08 32.4 14.2 0.0012 19.0 2.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX86017.1 - 1.7e-05 24.7 13.2 0.02 15.2 1.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger SpoIIIAH PF12685.2 KFX86017.1 - 0.021 14.3 1.5 0.056 12.9 1.0 1.7 1 0 0 1 1 1 0 SpoIIIAH-like protein PAS_9 PF13426.1 KFX86019.1 - 2.3e-11 44.0 0.0 5.1e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 PAS domain 7TMR-DISMED2 PF07696.6 KFX86021.1 - 0.036 13.5 0.0 0.048 13.1 0.0 1.1 1 0 0 1 1 1 0 7TMR-DISM extracellular 2 CDC14 PF08045.6 KFX86022.1 - 1.8e-76 256.6 0.0 2.2e-76 256.4 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component PBP1_TM PF14812.1 KFX86023.1 - 0.73 10.1 4.2 1.4 9.2 2.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosom_S12_S23 PF00164.20 KFX86026.1 - 6.6e-40 135.3 2.3 8.2e-40 135.0 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Glyco_transf_15 PF01793.11 KFX86027.1 - 0.0029 16.5 0.4 0.0035 16.3 0.2 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase EGF_3 PF12947.2 KFX86027.1 - 0.076 12.9 1.9 0.12 12.4 1.3 1.3 1 0 0 1 1 1 0 EGF domain DUF899 PF05988.7 KFX86029.1 - 9e-79 263.7 0.0 1e-78 263.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA PF00578.16 KFX86029.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Methyltransf_21 PF05050.7 KFX86034.1 - 0.041 13.8 0.1 0.051 13.5 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase FkbM domain Pro_CA PF00484.14 KFX86036.1 - 2.5e-29 102.2 0.1 2.9e-29 102.0 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase AAA PF00004.24 KFX86040.1 - 1.1e-38 132.4 0.0 3.1e-38 130.9 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFX86040.1 - 3.2e-08 33.7 1.1 1.9e-05 24.7 0.1 3.1 1 1 1 2 2 2 1 AAA domain Vps4_C PF09336.5 KFX86040.1 - 8.3e-07 28.8 0.0 2.9e-05 23.8 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 KFX86040.1 - 1.4e-06 27.5 0.0 2.5e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KFX86040.1 - 8.7e-05 22.5 1.7 0.0003 20.8 1.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 KFX86040.1 - 0.00018 21.2 0.1 0.0015 18.2 0.0 2.5 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KFX86040.1 - 0.0002 20.2 0.0 0.00029 19.6 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 KFX86040.1 - 0.00041 19.7 0.0 0.00067 19.1 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KFX86040.1 - 0.00043 19.9 0.1 0.007 16.0 0.0 2.5 2 1 0 2 2 2 1 Part of AAA domain Mg_chelatase PF01078.16 KFX86040.1 - 0.0012 18.0 0.1 0.0024 17.0 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KFX86040.1 - 0.0019 18.1 0.0 0.0061 16.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 KFX86040.1 - 0.0021 17.9 0.0 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KFX86040.1 - 0.0031 17.4 0.1 0.011 15.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFX86040.1 - 0.0038 18.0 0.1 0.015 16.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFX86040.1 - 0.0041 16.5 1.4 0.062 12.6 0.1 2.6 2 1 0 3 3 3 1 AAA domain AAA_28 PF13521.1 KFX86040.1 - 0.0052 16.7 0.8 0.04 13.8 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.1 KFX86040.1 - 0.011 15.3 0.1 0.019 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 KFX86040.1 - 0.018 13.9 0.0 0.029 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_11 PF13086.1 KFX86040.1 - 0.02 14.4 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFX86040.1 - 0.026 14.8 0.0 0.052 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 KFX86040.1 - 0.028 14.0 0.0 0.094 12.3 0.0 1.8 1 1 1 2 2 2 0 NACHT domain Sigma54_activat PF00158.21 KFX86040.1 - 0.028 13.8 0.0 0.15 11.4 0.0 2.2 1 1 2 3 3 3 0 Sigma-54 interaction domain PhoH PF02562.11 KFX86040.1 - 0.031 13.4 0.0 0.09 12.0 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Arch_ATPase PF01637.13 KFX86040.1 - 0.047 13.3 0.0 0.11 12.1 0.0 1.7 2 0 0 2 2 1 0 Archaeal ATPase ABC_tran PF00005.22 KFX86040.1 - 0.055 13.7 0.0 0.11 12.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Guanylate_kin PF00625.16 KFX86040.1 - 0.058 12.8 0.0 0.18 11.2 0.0 1.8 1 1 0 1 1 1 0 Guanylate kinase Zeta_toxin PF06414.7 KFX86040.1 - 0.086 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin KaiC PF06745.8 KFX86040.1 - 0.1 11.7 0.1 0.96 8.5 0.0 2.0 1 1 1 2 2 2 0 KaiC Sigma54_activ_2 PF14532.1 KFX86040.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 KFX86040.1 - 0.12 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase SRPRB PF09439.5 KFX86040.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF2075 PF09848.4 KFX86040.1 - 0.17 10.8 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Ribosomal_S17 PF00366.15 KFX86041.1 - 1.3e-08 34.7 0.8 1.3e-08 34.7 0.5 1.5 2 0 0 2 2 2 1 Ribosomal protein S17 WSN PF02206.13 KFX86041.1 - 0.0048 16.6 0.0 0.0087 15.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function Peptidase_M15_3 PF08291.6 KFX86041.1 - 0.046 13.5 0.1 11 5.8 0.0 2.4 2 0 0 2 2 2 0 Peptidase M15 ADH_N PF08240.7 KFX86043.1 - 3.4e-19 68.5 0.4 1.5e-18 66.5 0.1 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 KFX86043.1 - 0.0025 17.4 3.3 0.0097 15.5 2.3 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Methyltransf_23 PF13489.1 KFX86046.1 - 4.9e-15 55.6 0.0 7.4e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX86046.1 - 9e-07 29.4 0.1 1.1e-05 25.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX86046.1 - 9.9e-06 25.9 0.0 1.9e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX86046.1 - 4.7e-05 23.0 0.0 0.00078 19.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX86046.1 - 0.00025 20.2 0.0 0.64 9.0 0.0 2.6 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KFX86046.1 - 0.00065 20.1 0.0 0.0051 17.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX86046.1 - 0.0022 18.3 0.0 0.0085 16.4 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX86046.1 - 0.038 14.0 0.0 0.24 11.4 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 KFX86046.1 - 0.059 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein FtsJ PF01728.14 KFX86046.1 - 0.13 12.2 0.1 0.18 11.7 0.1 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase ATP-synt_DE_N PF02823.11 KFX86050.1 - 1.2e-15 56.9 0.1 2e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain TPR_11 PF13414.1 KFX86053.1 - 5.3e-28 96.4 14.5 2.9e-10 39.6 0.2 3.6 1 1 3 5 5 5 5 TPR repeat TPR_2 PF07719.12 KFX86053.1 - 9e-25 84.5 2.8 5.9e-05 22.6 0.1 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 KFX86053.1 - 4.3e-22 76.7 6.8 4.1e-06 26.1 0.0 5.4 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 KFX86053.1 - 1.6e-17 63.2 4.7 3e-07 30.2 0.1 3.9 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFX86053.1 - 3.4e-16 59.4 0.2 2.6e-05 24.7 0.2 3.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFX86053.1 - 4.1e-13 48.0 1.6 0.012 15.2 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFX86053.1 - 8e-13 47.7 1.0 0.019 15.5 0.2 4.5 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_19 PF14559.1 KFX86053.1 - 3.5e-12 46.4 2.8 2.9e-07 30.7 0.7 3.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFX86053.1 - 4.7e-11 41.6 5.0 0.028 14.1 0.2 4.6 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 KFX86053.1 - 6.8e-10 38.3 0.1 0.018 15.1 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KFX86053.1 - 2.6e-09 37.0 2.6 5.3e-05 23.2 0.2 3.2 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KFX86053.1 - 5.4e-06 26.1 1.3 0.0071 16.1 0.4 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 KFX86053.1 - 7.3e-05 22.5 5.0 0.091 12.7 0.3 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 KFX86053.1 - 0.0001 21.4 0.9 0.0058 15.7 1.1 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFX86053.1 - 0.00064 20.0 10.5 1.7 9.2 0.3 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TOM20_plant PF06552.7 KFX86053.1 - 0.0012 18.5 0.3 0.016 14.8 0.0 2.4 2 1 1 3 3 3 1 Plant specific mitochondrial import receptor subunit TOM20 SHNi-TPR PF10516.4 KFX86053.1 - 0.0012 18.0 1.6 0.28 10.4 0.0 2.8 3 0 0 3 3 3 2 SHNi-TPR DUF3856 PF12968.2 KFX86053.1 - 0.0019 18.0 1.0 0.71 9.6 0.0 3.2 3 1 0 3 3 3 1 Domain of Unknown Function (DUF3856) Phage_CP76 PF06892.6 KFX86053.1 - 0.022 14.0 0.0 0.044 13.0 0.0 1.7 1 1 0 1 1 1 0 Phage regulatory protein CII (CP76) Sel1 PF08238.7 KFX86053.1 - 0.031 14.9 3.1 0.2 12.3 0.1 3.1 3 0 0 3 3 3 0 Sel1 repeat RPN7 PF10602.4 KFX86053.1 - 0.04 13.3 0.2 0.82 9.0 0.0 2.2 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_21 PF09976.4 KFX86053.1 - 0.08 12.8 4.5 2.1 8.2 0.4 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Helicase_C PF00271.26 KFX86057.1 - 1.5e-05 24.7 0.0 2.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2695 PF10905.3 KFX86057.1 - 3.9 7.2 11.4 1.5 8.6 0.0 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2695) SH3_1 PF00018.23 KFX86058.1 - 2.4e-05 23.6 0.0 2.4e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFX86058.1 - 0.0042 16.6 0.0 0.0098 15.4 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Abhydro_lipase PF04083.11 KFX86060.1 - 5.3e-19 67.3 0.0 1.1e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 KFX86060.1 - 4.2e-08 33.3 1.5 6.9e-08 32.6 1.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX86060.1 - 0.00084 19.1 0.1 0.0013 18.5 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX86060.1 - 0.0011 18.6 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chloroplast_duf PF14476.1 KFX86060.1 - 0.074 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Petal formation-expressed Abhydrolase_3 PF07859.8 KFX86062.1 - 3.8e-22 78.8 0.0 6.8e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KFX86062.1 - 2.3e-20 72.5 0.0 2.8e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 KFX86062.1 - 0.013 14.6 0.0 0.26 10.4 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFX86062.1 - 0.019 14.7 0.0 0.029 14.1 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase_phd PF10503.4 KFX86062.1 - 0.068 12.4 0.1 0.14 11.3 0.1 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase Glyco_trans_1_4 PF13692.1 KFX86064.1 - 1.2e-23 83.6 0.0 2.4e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 APH PF01636.18 KFX86065.1 - 3.1e-14 53.2 0.0 4.4e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX86065.1 - 0.08 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase SlyX PF04102.7 KFX86072.1 - 0.0007 19.9 0.2 0.0015 18.8 0.1 1.6 1 0 0 1 1 1 1 SlyX DUF641 PF04859.7 KFX86072.1 - 0.0036 17.0 0.8 0.0067 16.1 0.5 1.4 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Cast PF10174.4 KFX86072.1 - 0.0052 14.9 0.3 0.0068 14.5 0.2 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone Atg14 PF10186.4 KFX86072.1 - 0.034 13.1 2.0 0.048 12.5 1.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Bacillus_HBL PF05791.6 KFX86072.1 - 0.045 13.1 0.1 0.063 12.6 0.1 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) CENP-Q PF13094.1 KFX86072.1 - 0.051 13.6 1.1 0.085 12.8 0.8 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit bZIP_1 PF00170.16 KFX86072.1 - 0.065 13.1 1.7 0.14 12.1 1.2 1.6 1 0 0 1 1 1 0 bZIP transcription factor CENP-F_leu_zip PF10473.4 KFX86072.1 - 0.096 12.5 1.0 0.18 11.6 0.7 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RBD-FIP PF09457.5 KFX86072.1 - 0.24 11.2 1.1 0.5 10.2 0.0 2.1 3 0 0 3 3 3 0 FIP domain WD40 PF00400.27 KFX86077.1 - 2.8e-09 36.4 0.0 0.00014 21.5 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Zip PF02535.17 KFX86080.1 - 4.8e-07 29.0 0.7 8.2e-07 28.3 0.5 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter TauE PF01925.14 KFX86080.1 - 0.085 12.2 1.9 0.12 11.7 1.3 1.2 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE Cation_ATPase_C PF00689.16 KFX86080.1 - 0.11 12.0 2.6 5.2 6.5 0.1 2.2 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus DUF912 PF06024.7 KFX86086.1 - 0.018 15.1 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) gpUL132 PF11359.3 KFX86086.1 - 0.024 13.9 1.9 0.033 13.5 1.3 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 DUF4328 PF14219.1 KFX86086.1 - 0.037 13.3 0.1 0.054 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Plasmodium_Vir PF05795.6 KFX86086.1 - 0.048 12.8 0.6 0.052 12.7 0.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Alpha_GJ PF03229.8 KFX86086.1 - 0.055 13.8 5.0 0.079 13.3 3.5 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J TrbC PF04956.8 KFX86086.1 - 0.078 13.0 0.7 0.11 12.4 0.5 1.2 1 0 0 1 1 1 0 TrbC/VIRB2 family SSP160 PF06933.6 KFX86086.1 - 3.8 5.3 11.6 4.6 5.1 8.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ADH_zinc_N PF00107.21 KFX86089.1 - 1.1e-09 37.8 0.0 2.3e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX86089.1 - 0.00046 19.9 0.0 0.00078 19.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.11 KFX86090.1 - 8.7e-22 77.2 12.6 1e-21 77.1 8.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX86090.1 - 1.3e-15 56.9 0.3 1.4e-15 56.8 0.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KFX86090.1 - 4e-07 28.6 0.4 4.2e-07 28.5 0.3 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KFX86090.1 - 9.2e-05 21.0 8.3 0.00015 20.3 5.8 1.3 1 1 0 1 1 1 1 MFS/sugar transport protein DUF3433 PF11915.3 KFX86090.1 - 0.21 11.7 4.7 2.1 8.5 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3433) Exo_endo_phos PF03372.18 KFX86093.1 - 7.7e-08 32.5 0.0 9.9e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 KFX86097.1 - 3.9e-13 48.7 11.5 2.8e-10 39.6 0.0 5.5 5 1 0 5 5 5 3 WD domain, G-beta repeat zf-C2H2_2 PF12756.2 KFX86100.1 - 0.077 13.1 0.2 0.13 12.3 0.2 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) MFS_1 PF07690.11 KFX86103.1 - 2.6e-35 121.7 24.5 3.8e-35 121.2 17.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.13 KFX86104.1 - 2.5e-06 27.2 3.0 2.5e-06 27.2 2.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2913 PF11140.3 KFX86104.1 - 0.0032 16.8 0.0 0.0078 15.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2913) RPN7 PF10602.4 KFX86106.1 - 2.5e-44 150.7 0.8 4.5e-44 149.9 0.5 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KFX86106.1 - 7.6e-14 51.9 1.0 2.8e-13 50.1 0.0 2.4 3 0 0 3 3 3 1 PCI domain DUF3227 PF11537.3 KFX86106.1 - 0.0088 16.1 0.0 0.061 13.4 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3227) TPR_2 PF07719.12 KFX86106.1 - 0.011 15.6 5.0 1.3 9.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1617 PF07761.7 KFX86106.1 - 0.049 13.6 0.3 0.12 12.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1617) TPR_1 PF00515.23 KFX86106.1 - 0.15 11.7 7.9 3 7.5 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFX86106.1 - 0.15 11.8 3.7 5.4 7.0 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Mito_carr PF00153.22 KFX86109.1 - 1.5e-19 69.5 0.2 2.6e-19 68.6 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial carrier protein Chitin_bind_3 PF03067.10 KFX86109.1 - 2.8e-08 34.2 1.4 3.5e-08 33.9 1.0 1.1 1 0 0 1 1 1 1 Chitin binding domain DUF2416 PF10315.4 KFX86118.1 - 1.8e-05 24.9 0.2 2.1e-05 24.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2416) HupE_UreJ PF04955.7 KFX86118.1 - 0.078 12.2 1.3 0.11 11.8 0.9 1.2 1 0 0 1 1 1 0 HupE / UreJ protein Y_phosphatase2 PF03162.8 KFX86119.1 - 9.4e-48 161.6 0.0 1.3e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 KFX86119.1 - 5.1e-10 39.8 0.0 6.4e-09 36.2 0.0 2.3 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KFX86119.1 - 0.0041 16.4 0.1 0.0063 15.8 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFX86119.1 - 0.0098 15.4 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Amidohydro_5 PF13594.1 KFX86123.1 - 4.6e-16 58.3 1.2 9.9e-16 57.3 0.8 1.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KFX86123.1 - 7.7e-10 38.9 0.3 9.4e-10 38.6 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KFX86123.1 - 3.8e-05 23.8 0.1 6.9e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KFX86123.1 - 0.066 12.4 1.0 0.094 11.9 0.7 1.4 1 1 0 1 1 1 0 Amidohydrolase family GWT1 PF06423.7 KFX86125.1 - 0.057 13.5 0.1 0.093 12.8 0.1 1.3 1 0 0 1 1 1 0 GWT1 Epimerase PF01370.16 KFX86130.1 - 5.1e-13 48.9 0.0 6e-12 45.5 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX86130.1 - 3.4e-10 40.2 0.2 3.4e-10 40.2 0.2 1.6 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KFX86130.1 - 6.6e-09 35.3 1.1 7.2e-09 35.2 0.1 1.5 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.7 KFX86130.1 - 2e-06 26.8 0.1 3.4e-05 22.8 0.0 2.2 1 1 1 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 KFX86130.1 - 1.1e-05 24.2 0.1 0.0013 17.4 0.1 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KFX86130.1 - 0.0014 18.9 0.0 0.0028 17.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KFX86130.1 - 0.018 14.0 0.1 0.029 13.3 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 KFX86130.1 - 0.022 13.6 0.1 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 KFX86130.1 - 0.036 13.9 0.0 0.06 13.2 0.0 1.6 1 1 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.13 KFX86130.1 - 0.081 12.9 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain DapB_N PF01113.15 KFX86130.1 - 0.092 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Fanconi_A PF03511.9 KFX86137.1 - 0.44 10.3 2.3 0.67 9.7 0.2 2.0 2 0 0 2 2 2 0 Fanconi anaemia group A protein Nop14 PF04147.7 KFX86140.1 - 0.0018 16.3 13.1 0.0018 16.3 9.1 2.8 3 0 0 3 3 3 2 Nop14-like family DbpA PF03880.10 KFX86140.1 - 0.051 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 DbpA RNA binding domain PX PF00787.19 KFX86141.1 - 2.1e-13 50.0 0.0 3.2e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 PX domain Spt5-NGN PF03439.8 KFX86143.1 - 0.057 13.1 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section DHDPS PF00701.17 KFX86144.1 - 7.5e-27 93.6 0.1 9.3e-27 93.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Mito_carr PF00153.22 KFX86149.1 - 3.1e-47 158.2 0.3 2.4e-25 88.0 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF3320 PF11784.3 KFX86149.1 - 0.15 11.6 0.0 3.3 7.2 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3320) 1-cysPrx_C PF10417.4 KFX86150.1 - 0.14 11.8 1.5 0.26 10.9 1.0 1.5 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin Bac_rhamnosid PF05592.6 KFX86151.1 - 6.6e-31 107.0 0.1 7.5e-31 106.9 0.0 1.0 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase MBD PF01429.14 KFX86151.1 - 0.1 12.1 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyl-CpG binding domain Yae1_N PF09811.4 KFX86153.1 - 3.8e-11 42.3 1.3 8.7e-11 41.1 0.9 1.7 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Romo1 PF10247.4 KFX86153.1 - 0.031 14.4 0.6 0.055 13.6 0.4 1.4 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 CpXC PF14353.1 KFX86155.1 - 0.084 12.8 0.1 0.094 12.6 0.1 1.1 1 0 0 1 1 1 0 CpXC protein GPI-anchored PF10342.4 KFX86156.1 - 1.9e-20 73.1 1.0 1.9e-20 73.1 0.7 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family SoxZ PF08770.6 KFX86156.1 - 0.08 12.3 0.2 0.61 9.5 0.0 2.2 1 1 1 2 2 2 0 Sulphur oxidation protein SoxZ DUF3827 PF12877.2 KFX86156.1 - 0.42 8.6 6.4 0.56 8.2 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) IER PF05760.7 KFX86156.1 - 1 9.2 7.5 1.2 9.0 5.2 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) Mitofilin PF09731.4 KFX86156.1 - 2.2 6.8 7.0 2.6 6.5 4.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MIP-T3 PF10243.4 KFX86156.1 - 2.7 6.3 9.7 3.4 6.0 6.7 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Presenilin PF01080.12 KFX86156.1 - 7.8 5.2 9.6 9.7 4.8 6.6 1.1 1 0 0 1 1 1 0 Presenilin UBX PF00789.15 KFX86160.1 - 1.4e-07 31.4 0.0 3e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 UBX domain Trypan_PARP PF05887.6 KFX86160.1 - 0.51 10.1 7.7 0.87 9.3 5.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NAD_binding_6 PF08030.7 KFX86171.1 - 0.0043 16.9 0.0 0.005 16.7 0.0 1.0 1 0 0 1 1 1 1 Ferric reductase NAD binding domain ACOX PF01756.14 KFX86180.1 - 1.1e-37 129.2 0.0 2.3e-37 128.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase p450 PF00067.17 KFX86186.1 - 4.1e-44 150.8 0.0 5.8e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 EF-hand_7 PF13499.1 KFX86189.1 - 2.6e-13 49.8 0.5 1.3e-09 38.0 0.1 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFX86189.1 - 1.5e-10 40.0 0.3 0.0057 16.4 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KFX86189.1 - 1.4e-08 33.4 0.1 0.013 14.7 0.0 3.7 3 1 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 KFX86189.1 - 5.4e-07 29.4 0.0 0.031 14.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KFX86189.1 - 3.9e-06 26.3 0.3 0.00066 19.2 0.1 3.4 2 2 2 4 4 4 1 EF-hand domain pair UPF0154 PF03672.8 KFX86189.1 - 0.038 13.5 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) DUF3216 PF11505.3 KFX86189.1 - 0.053 13.3 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) EF-hand_5 PF13202.1 KFX86189.1 - 3.8 7.0 5.4 2.2 7.7 0.7 2.6 2 0 0 2 2 2 0 EF hand BChl_A PF02327.12 KFX86191.1 - 0.025 13.2 0.1 0.03 12.9 0.1 1.1 1 0 0 1 1 1 0 Bacteriochlorophyll A protein PAPS_reduct PF01507.14 KFX86192.1 - 2.3e-25 89.4 0.0 3.4e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family SpoU_methylas_C PF12105.3 KFX86192.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal adh_short_C2 PF13561.1 KFX86203.1 - 1.6e-26 93.5 0.0 1.9e-26 93.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFX86203.1 - 3.5e-15 56.3 0.1 5e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX86203.1 - 1.3e-05 24.9 0.0 3.5e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KFX86203.1 - 0.00028 20.9 0.0 0.00052 20.0 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KFX86203.1 - 0.00064 19.4 0.2 0.0013 18.5 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KFX86203.1 - 0.0028 16.7 0.0 0.0051 15.9 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 KFX86203.1 - 0.0075 16.5 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding ADH_zinc_N PF00107.21 KFX86206.1 - 3e-17 62.3 0.0 5e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX86206.1 - 2.8e-10 39.9 3.1 5e-10 39.1 2.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFX86206.1 - 0.00015 22.6 0.0 0.0003 21.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KFX86206.1 - 0.0052 15.9 0.2 0.0081 15.3 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KFX86206.1 - 0.022 14.8 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KFX86209.1 - 2.1e-19 70.2 1.2 3.5e-19 69.5 0.8 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX86209.1 - 2.3e-06 27.2 0.0 2.9e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 KFX86209.1 - 0.056 13.2 0.0 0.098 12.4 0.0 1.5 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain NmrA PF05368.8 KFX86209.1 - 0.068 12.4 0.1 0.31 10.2 0.0 2.0 2 1 0 2 2 2 0 NmrA-like family TT_ORF2 PF02957.10 KFX86215.1 - 0.18 12.4 1.9 0.28 11.9 1.2 1.5 1 1 0 1 1 1 0 TT viral ORF2 adh_short PF00106.20 KFX86216.1 - 4.9e-16 59.0 0.5 5.9e-16 58.8 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX86216.1 - 5.7e-09 35.8 0.2 6.9e-09 35.6 0.2 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFX86216.1 - 6e-06 26.2 0.1 7.1e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFX86216.1 - 0.00047 19.6 0.1 0.00059 19.3 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KFX86216.1 - 0.0031 17.2 1.5 0.0038 16.9 0.1 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pkinase PF00069.20 KFX86220.1 - 0.014 14.5 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Pkinase_C PF00433.19 KFX86222.1 - 0.011 16.1 0.1 0.022 15.2 0.1 1.5 1 0 0 1 1 1 0 Protein kinase C terminal domain LDB19 PF13002.2 KFX86224.1 - 0.0013 18.2 0.2 0.002 17.6 0.1 1.2 1 0 0 1 1 1 1 Arrestin_N terminal like Nucleoplasmin PF03066.10 KFX86227.1 - 0.017 14.6 3.4 0.023 14.2 2.4 1.2 1 0 0 1 1 1 0 Nucleoplasmin Trypan_PARP PF05887.6 KFX86227.1 - 0.75 9.6 4.4 1.2 8.9 3.0 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ribosomal_L6e PF01159.14 KFX86227.1 - 1.1 9.5 5.2 2.2 8.5 3.6 1.4 1 0 0 1 1 1 0 Ribosomal protein L6e MFS_1_like PF12832.2 KFX86231.1 - 2.8e-05 23.8 0.0 2.8e-05 23.8 0.0 3.2 4 0 0 4 4 4 1 MFS_1 like family MFS_1 PF07690.11 KFX86234.1 - 3.4e-07 29.2 16.5 4.7e-06 25.5 12.2 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily NACHT PF05729.7 KFX86235.1 - 4.4e-09 36.2 0.1 8.3e-09 35.3 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KFX86235.1 - 5.7e-05 23.1 0.2 0.00041 20.4 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.9 KFX86235.1 - 6.5e-05 22.0 0.6 0.24 10.3 0.1 2.5 3 0 0 3 3 3 2 KAP family P-loop domain AAA_22 PF13401.1 KFX86235.1 - 0.0048 17.0 0.0 0.065 13.3 0.0 2.4 1 1 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 KFX86235.1 - 0.086 12.3 0.0 2.4 7.6 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 KFX86235.1 - 0.1 12.0 0.0 1.2 8.5 0.0 2.4 3 0 0 3 3 3 0 AAA domain WLM PF08325.5 KFX86236.1 - 3.4e-48 163.9 0.3 5.5e-48 163.3 0.2 1.3 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.12 KFX86236.1 - 2.1e-08 34.2 1.1 4e-08 33.2 0.7 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 DUF2689 PF10894.3 KFX86236.1 - 0.065 13.0 0.0 0.16 11.7 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2689) DUF1713 PF08213.6 KFX86239.1 - 2.7e-14 52.4 20.1 2.7e-14 52.4 13.9 1.7 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) UBA PF00627.26 KFX86240.1 - 3.5e-08 33.0 0.1 5.5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 UBA/TS-N domain Ank_2 PF12796.2 KFX86247.1 - 1.1e-87 288.4 1.6 2.8e-18 66.0 0.0 4.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFX86247.1 - 1.8e-65 216.2 0.5 2.3e-12 47.0 0.0 8.3 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.25 KFX86247.1 - 2.2e-64 210.2 0.2 2.1e-07 30.3 0.0 9.6 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 KFX86247.1 - 6.9e-47 156.4 0.7 6.4e-09 35.7 0.0 7.0 1 1 7 8 8 8 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX86247.1 - 3.7e-42 138.0 0.8 0.00035 20.5 0.0 9.4 9 0 0 9 9 9 8 Ankyrin repeat HTH_21 PF13276.1 KFX86247.1 - 0.0016 18.3 0.0 32 4.6 0.0 4.8 4 1 1 5 5 5 0 HTH-like domain DUF348 PF03990.9 KFX86247.1 - 0.0064 16.0 2.1 20 4.8 0.0 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF348) VBS PF08913.5 KFX86247.1 - 0.14 12.3 0.0 7.5 6.8 0.0 3.0 2 1 1 3 3 3 0 Vinculin Binding Site cNMP_binding PF00027.24 KFX86248.1 - 7.8e-42 141.0 0.0 3.6e-20 71.5 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain GXGXG PF01493.14 KFX86248.1 - 0.062 12.2 0.0 0.61 9.0 0.0 2.1 2 0 0 2 2 2 0 GXGXG motif PTH2 PF01981.11 KFX86250.1 - 5.3e-44 148.6 0.1 6.3e-44 148.3 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 EHN PF06441.7 KFX86255.1 - 7.6e-23 80.5 0.0 1e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KFX86255.1 - 0.0082 16.0 0.4 0.016 15.0 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Spindle_Spc25 PF08234.7 KFX86264.1 - 3.1e-21 75.1 0.0 1.6e-20 72.8 0.0 2.1 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 ERM PF00769.14 KFX86264.1 - 0.076 12.5 15.0 0.13 11.7 10.4 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ApoO PF09769.4 KFX86264.1 - 0.1 12.3 0.4 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 Apolipoprotein O Spc7 PF08317.6 KFX86264.1 - 0.18 10.4 4.2 0.24 9.9 2.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein L_lactis_ph-MCP PF06673.6 KFX86264.1 - 0.25 10.0 3.3 0.48 9.1 2.3 1.4 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein AAA_13 PF13166.1 KFX86264.1 - 0.29 9.5 3.2 0.37 9.1 2.2 1.1 1 0 0 1 1 1 0 AAA domain Macoilin PF09726.4 KFX86264.1 - 0.66 8.1 8.1 0.83 7.8 5.6 1.0 1 0 0 1 1 1 0 Transmembrane protein Atg14 PF10186.4 KFX86264.1 - 0.88 8.4 4.3 1.1 8.0 3.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 PRTP PF01366.13 KFX86264.1 - 0.98 7.3 4.3 1.2 7.0 3.0 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein APG6 PF04111.7 KFX86264.1 - 3.1 6.7 6.8 4.4 6.2 4.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KFX86264.1 - 8.9 5.8 8.6 14 5.1 6.0 1.4 1 0 0 1 1 1 0 IncA protein Caleosin PF05042.8 KFX86267.1 - 0.035 13.6 0.1 0.097 12.2 0.0 1.7 2 0 0 2 2 2 0 Caleosin related protein DUF1314 PF07013.6 KFX86267.1 - 0.1 11.9 0.1 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1314) Corona_nucleoca PF00937.13 KFX86269.1 - 0.0081 15.1 17.6 0.079 11.8 6.4 2.1 2 0 0 2 2 2 2 Coronavirus nucleocapsid protein SOG2 PF10428.4 KFX86269.1 - 0.1 11.2 2.0 0.15 10.7 1.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF566 PF04484.7 KFX86269.1 - 0.17 11.4 8.3 0.072 12.5 1.5 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF566) DUF1509 PF07420.6 KFX86269.1 - 0.27 10.4 25.4 0.48 9.6 7.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1509) MRI PF15325.1 KFX86269.1 - 2 9.4 12.6 0.4 11.6 0.9 3.2 3 0 0 3 3 3 0 Modulator of retrovirus infection BLOC1_2 PF10046.4 KFX86270.1 - 0.091 12.9 0.2 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MFS_1 PF07690.11 KFX86272.1 - 2.1e-07 29.9 31.4 2.1e-07 29.9 21.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily APG6 PF04111.7 KFX86276.1 - 0.0018 17.3 8.0 0.0027 16.8 5.5 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 Fez1 PF06818.10 KFX86276.1 - 0.0059 16.6 8.4 0.013 15.4 5.0 1.8 2 0 0 2 2 2 1 Fez1 HALZ PF02183.13 KFX86276.1 - 0.012 15.3 3.9 0.012 15.3 2.7 2.9 3 1 1 4 4 4 0 Homeobox associated leucine zipper IncA PF04156.9 KFX86276.1 - 0.049 13.2 7.9 0.085 12.4 5.5 1.3 1 0 0 1 1 1 0 IncA protein Mod_r PF07200.8 KFX86276.1 - 0.06 13.2 8.3 0.094 12.6 5.7 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein TPR_MLP1_2 PF07926.7 KFX86276.1 - 0.069 12.8 5.1 0.19 11.4 3.5 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3584 PF12128.3 KFX86276.1 - 0.081 10.2 8.1 0.11 9.7 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc24 PF08286.6 KFX86276.1 - 0.33 10.6 5.4 11 5.6 0.1 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 AAA_27 PF13514.1 KFX86276.1 - 0.46 8.1 11.4 0.65 7.6 7.9 1.1 1 0 0 1 1 1 0 AAA domain COG5 PF10392.4 KFX86276.1 - 0.5 10.3 3.9 0.87 9.5 1.7 2.0 2 1 0 2 2 2 0 Golgi transport complex subunit 5 DUF972 PF06156.8 KFX86276.1 - 0.52 10.6 4.5 2 8.7 3.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) WEMBL PF05701.6 KFX86276.1 - 0.56 8.6 13.1 0.93 7.8 9.1 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Macoilin PF09726.4 KFX86276.1 - 1.1 7.4 7.5 1.6 6.8 5.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Spc7 PF08317.6 KFX86276.1 - 1.2 7.7 6.8 1.9 7.0 4.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 KFX86276.1 - 2.4 8.0 13.0 27 4.6 7.7 2.6 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uds1 PF15456.1 KFX86276.1 - 2.8 7.9 11.5 2.7 7.9 6.6 1.8 2 0 0 2 2 2 0 Up-regulated During Septation Snf7 PF03357.16 KFX86276.1 - 3.3 7.0 9.8 5.3 6.4 4.7 2.0 2 0 0 2 2 2 0 Snf7 DUF4200 PF13863.1 KFX86276.1 - 3.8 7.4 16.2 2.3 8.2 6.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) DivIVA PF05103.8 KFX86276.1 - 4.1 7.4 12.5 0.84 9.6 6.2 1.6 2 0 0 2 2 2 0 DivIVA protein GAS PF13851.1 KFX86276.1 - 5.3 6.1 11.9 1.6 7.8 5.7 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 KFX86276.1 - 6 6.4 12.7 1.1 8.7 3.5 2.9 2 1 1 3 3 3 0 Septum formation initiator ZapA PF05164.8 KFX86276.1 - 6.9 6.7 9.2 6.6 6.7 4.3 2.0 2 0 0 2 2 2 0 Cell division protein ZapA Cupin_1 PF00190.17 KFX86278.1 - 3.6e-13 49.1 0.4 7.2e-13 48.1 0.3 1.5 1 0 0 1 1 1 1 Cupin tify PF06200.9 KFX86278.1 - 0.0071 15.5 0.0 0.017 14.3 0.0 1.6 1 0 0 1 1 1 1 tify domain Hid1 PF12722.2 KFX86279.1 - 0.97 7.0 3.8 1.6 6.3 2.6 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.4 KFX86279.1 - 6.1 5.0 6.4 8.2 4.5 4.4 1.2 1 0 0 1 1 1 0 Transmembrane protein EzrA PF06160.7 KFX86281.1 - 0.0072 14.5 1.6 0.02 13.1 0.0 1.9 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA Transglut_core3 PF13471.1 KFX86281.1 - 0.069 12.9 0.7 1.1 9.1 0.1 2.6 2 1 0 2 2 2 0 Transglutaminase-like superfamily Seryl_tRNA_N PF02403.17 KFX86281.1 - 0.27 11.2 12.7 0.11 12.4 4.3 2.5 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF972 PF06156.8 KFX86281.1 - 3.9 7.8 5.6 11 6.4 0.6 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF972) HALZ PF02183.13 KFX86281.1 - 6 6.6 6.1 2.8 7.7 0.1 3.2 3 1 1 4 4 4 0 Homeobox associated leucine zipper TSC22 PF01166.13 KFX86281.1 - 8.4 6.4 8.1 3.3 7.7 1.8 2.8 2 1 1 3 3 3 0 TSC-22/dip/bun family Sec10 PF07393.6 KFX86287.1 - 7e-141 470.7 2.7 7.9e-141 470.6 1.9 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 zf-RING_2 PF13639.1 KFX86297.1 - 6.8e-10 38.6 7.9 1.1e-09 37.9 5.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFX86297.1 - 2.1e-09 37.3 1.3 4.8e-09 36.1 0.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KFX86297.1 - 4.2e-07 29.7 2.1 8.5e-07 28.7 1.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 KFX86297.1 - 1.2e-06 28.0 8.9 2.1e-06 27.2 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KFX86297.1 - 6.7e-06 25.9 8.1 2.1e-05 24.3 5.6 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 KFX86297.1 - 0.00011 22.2 9.0 0.0002 21.3 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFX86297.1 - 0.00019 21.0 5.5 0.00034 20.2 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 KFX86297.1 - 0.00046 20.1 7.5 0.00094 19.1 5.2 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING_5 PF14634.1 KFX86297.1 - 0.0014 18.2 8.7 0.0025 17.5 6.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain C1_1 PF00130.17 KFX86297.1 - 0.0041 16.8 4.0 0.0041 16.8 2.8 2.0 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Baculo_RING PF05883.6 KFX86297.1 - 0.026 14.3 0.5 0.049 13.4 0.3 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.1 KFX86297.1 - 0.046 13.3 5.1 0.69 9.5 3.5 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 KFX86297.1 - 0.39 10.2 3.3 0.73 9.4 2.3 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 KFX86297.1 - 0.43 10.3 3.6 1.7 8.4 2.5 1.8 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-RING-like PF08746.6 KFX86297.1 - 0.57 10.2 9.0 0.5 10.4 4.5 2.1 2 0 0 2 2 2 0 RING-like domain Prok-RING_1 PF14446.1 KFX86297.1 - 0.58 9.9 3.6 21 4.9 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 KFX86297.1 - 0.89 9.2 7.0 1.9 8.2 4.9 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.1 KFX86297.1 - 2.6 7.8 6.9 5.3 6.8 4.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger Nop14 PF04147.7 KFX86299.1 - 0.24 9.2 18.8 0.31 8.9 13.0 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 KFX86299.1 - 0.3 10.0 18.6 0.4 9.6 12.9 1.2 1 0 0 1 1 1 0 BUD22 Sugar_tr PF00083.19 KFX86301.1 - 2e-75 254.0 24.5 5.7e-75 252.6 17.0 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX86301.1 - 1.2e-26 93.2 43.7 1.2e-19 70.2 10.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFX86301.1 - 6.9e-05 22.5 2.4 0.037 13.8 0.1 3.3 3 0 0 3 3 3 2 MFS_1 like family eIF-6 PF01912.13 KFX86303.1 - 1.9e-82 275.1 1.2 2.7e-82 274.6 0.8 1.2 1 0 0 1 1 1 1 eIF-6 family Phage_holin_6 PF10746.4 KFX86303.1 - 0.059 13.1 0.1 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Phage holin family 6 Dmrt1 PF12374.3 KFX86305.1 - 0.25 11.6 2.1 0.46 10.8 1.5 1.4 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 O-FucT PF10250.4 KFX86306.1 - 0.094 11.8 0.0 0.35 9.9 0.0 1.8 2 0 0 2 2 2 0 GDP-fucose protein O-fucosyltransferase FLgD_tudor PF13861.1 KFX86308.1 - 0.11 12.4 0.4 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 FlgD Tudor-like domain DUF4446 PF14584.1 KFX86309.1 - 2.5 7.9 5.6 0.26 11.0 0.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) MMR_HSR1 PF01926.18 KFX86310.1 - 1.7e-12 47.2 0.0 4.5e-12 45.9 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFX86310.1 - 0.00034 19.9 0.0 0.0011 18.3 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B MobB PF03205.9 KFX86310.1 - 0.017 14.8 0.4 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PPAK PF02818.10 KFX86310.1 - 0.029 14.2 2.2 0.084 12.7 1.5 1.8 1 0 0 1 1 1 0 PPAK motif AAA_14 PF13173.1 KFX86310.1 - 0.048 13.5 0.0 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KFX86310.1 - 0.063 14.1 0.1 0.48 11.2 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KFX86310.1 - 0.078 13.2 4.1 0.59 10.4 2.9 2.3 1 1 0 1 1 1 0 AAA domain SHMT PF00464.14 KFX86312.1 - 1.2e-127 425.6 0.0 1.4e-127 425.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 KFX86312.1 - 0.058 12.3 0.0 0.11 11.4 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class I and II RNA_POL_M_15KD PF02150.11 KFX86313.1 - 4.7e-08 32.5 0.4 6.9e-08 32.0 0.3 1.3 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit GFA PF04828.9 KFX86313.1 - 0.027 14.3 0.0 0.027 14.3 0.0 1.1 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme TPP_enzyme_C PF02775.16 KFX86318.1 - 4.9e-45 152.8 0.0 5.8e-45 152.5 0.0 1.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain RRM_1 PF00076.17 KFX86320.1 - 2.3e-39 132.8 0.3 7.4e-19 67.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX86320.1 - 1.5e-27 95.3 0.1 2e-12 46.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX86320.1 - 2.9e-15 55.8 0.0 1.6e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 KFX86320.1 - 0.055 13.2 0.1 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Nop14 PF04147.7 KFX86321.1 - 0.0033 15.4 12.8 0.0042 15.0 8.9 1.0 1 0 0 1 1 1 1 Nop14-like family BAF1_ABF1 PF04684.8 KFX86321.1 - 1.5 7.6 5.2 2 7.1 3.6 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Molybdopterin PF00384.17 KFX86322.1 - 1.8e-28 99.5 0.0 2.4e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase DUF1982 PF09326.6 KFX86322.1 - 1.6e-15 57.0 0.0 3.2e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) PP-binding PF00550.20 KFX86324.1 - 1.7e-05 24.9 0.0 3.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.23 KFX86324.1 - 7e-05 21.3 0.1 0.00013 20.5 0.1 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Ribosomal_L4 PF00573.17 KFX86326.1 - 1.8e-24 86.1 0.0 2.1e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Stm1_N PF09598.5 KFX86327.1 - 0.57 10.9 7.5 1.4 9.6 5.2 1.8 1 0 0 1 1 1 0 Stm1 CAF-1_p150 PF11600.3 KFX86328.1 - 0.0042 16.5 21.0 0.0058 16.0 14.5 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ycf1 PF05758.7 KFX86328.1 - 0.052 11.2 5.1 0.055 11.1 3.5 1.0 1 0 0 1 1 1 0 Ycf1 DUF92 PF01940.11 KFX86328.1 - 0.056 12.5 0.7 0.078 12.1 0.5 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF92 MIP-T3 PF10243.4 KFX86328.1 - 0.073 11.5 19.2 0.082 11.3 13.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Auts2 PF15336.1 KFX86328.1 - 0.19 11.7 6.9 0.42 10.5 4.8 1.5 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein NCKAP5 PF15246.1 KFX86328.1 - 0.23 10.8 15.8 0.33 10.2 10.9 1.2 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein Spore_coat_CotO PF14153.1 KFX86328.1 - 0.71 9.2 11.6 0.89 8.9 8.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Asp-B-Hydro_N PF05279.6 KFX86328.1 - 0.75 9.6 12.3 0.97 9.2 8.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF2146 PF10220.4 KFX86328.1 - 1.4 6.8 8.1 1.6 6.5 5.6 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DUF106 PF01956.11 KFX86328.1 - 4.1 6.9 5.1 6.2 6.3 3.5 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 Borrelia_P83 PF05262.6 KFX86328.1 - 4.3 5.5 21.4 5.5 5.1 14.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Sec62 PF03839.11 KFX86328.1 - 4.8 6.5 8.2 6.4 6.1 5.7 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF2058 PF09831.4 KFX86328.1 - 9.1 6.1 17.5 14 5.4 12.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Abhydrolase_3 PF07859.8 KFX86330.1 - 3.3e-05 23.5 0.0 6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KFX86331.1 - 0.056 12.1 0.0 0.082 11.6 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX86331.1 - 0.06 12.9 1.2 0.17 11.4 0.4 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold DDE_1 PF03184.14 KFX86332.1 - 5.6e-51 172.7 0.1 9.5e-51 172.0 0.1 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_psq PF05225.11 KFX86332.1 - 2.8e-05 23.5 0.0 5.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_Tc5 PF03221.11 KFX86332.1 - 0.00023 20.8 1.9 0.0011 18.7 0.0 2.8 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain Lipase_GDSL PF00657.17 KFX86334.1 - 9.3e-16 58.3 0.4 1.2e-15 58.0 0.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KFX86334.1 - 1.6e-14 54.4 0.3 2e-14 54.1 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Abhydrolase_1 PF00561.15 KFX86335.1 - 1.6e-23 83.4 0.0 2.1e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFX86335.1 - 5.4e-06 26.4 0.1 6.4e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KFX86335.1 - 0.0037 17.1 0.0 0.0068 16.2 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_5 PF12695.2 KFX86335.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sec1 PF00995.18 KFX86337.1 - 2.3e-23 82.6 0.0 2.9e-23 82.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Lipoprotein_11 PF03260.8 KFX86339.1 - 0.076 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Lepidopteran low molecular weight (30 kD) lipoprotein 3HCDH_N PF02737.13 KFX86345.1 - 9.9e-33 113.2 0.0 1.4e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KFX86345.1 - 1.5e-09 38.1 0.0 3.3e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Herpes_UL32 PF06070.6 KFX86347.1 - 2.4 6.4 21.2 2.6 6.3 14.7 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Zip PF02535.17 KFX86349.1 - 7.6e-37 126.9 0.3 9e-37 126.7 0.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter YniB PF14002.1 KFX86349.1 - 0.063 12.7 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 YniB-like protein Glyco_hydro_7 PF00840.15 KFX86352.1 - 2.7e-34 118.2 0.1 2.7e-34 118.2 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 7 Pec_lyase_C PF00544.14 KFX86352.1 - 1.8e-17 63.5 0.5 2.6e-17 62.9 0.3 1.4 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KFX86352.1 - 0.00069 19.4 8.8 0.0033 17.1 6.0 2.0 1 1 0 1 1 1 1 Right handed beta helix region NosD PF05048.8 KFX86352.1 - 0.19 10.8 6.5 0.44 9.6 4.5 1.5 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) DoxX_3 PF13781.1 KFX86354.1 - 0.13 12.6 1.1 0.21 11.9 0.8 1.3 1 0 0 1 1 1 0 DoxX-like family DHFR_1 PF00186.14 KFX86360.1 - 1.1e-31 109.5 0.0 9.3e-25 87.0 0.0 2.4 2 1 0 2 2 2 2 Dihydrofolate reductase RRM_1 PF00076.17 KFX86362.1 - 1e-21 76.3 0.0 1.2e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX86362.1 - 1e-16 60.6 0.0 1.2e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX86362.1 - 1.1e-09 38.0 0.0 1.3e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Isochorismatase PF00857.15 KFX86363.1 - 5e-08 33.0 0.0 8.6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family MFS_1 PF07690.11 KFX86365.1 - 5.3e-24 84.5 19.5 6.3e-24 84.3 13.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.3 KFX86365.1 - 0.00018 20.1 4.1 0.00018 20.1 2.8 1.5 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like Epimerase PF01370.16 KFX86367.1 - 5.2e-20 71.8 0.1 1.5e-19 70.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFX86367.1 - 1.1e-10 40.8 0.0 1.1e-07 31.1 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KFX86367.1 - 1e-08 34.4 0.0 1.4e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KFX86367.1 - 2.3e-06 26.5 0.0 3.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KFX86367.1 - 2.8e-05 23.1 0.1 4.7e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KFX86367.1 - 0.034 14.0 1.6 0.23 11.3 0.3 2.1 2 0 0 2 2 2 0 short chain dehydrogenase Acyl_transf_1 PF00698.16 KFX86370.1 - 1.1e-39 136.6 0.0 1.4e-39 136.3 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain Pkinase PF00069.20 KFX86374.1 - 1.1e-64 218.1 0.0 1.5e-64 217.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX86374.1 - 2.1e-30 105.6 0.0 2.9e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX86374.1 - 1.2e-05 24.4 0.0 2.2e-05 23.5 0.0 1.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFX86374.1 - 0.064 12.9 0.1 0.34 10.6 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family AIF-MLS PF14962.1 KFX86378.1 - 0.041 13.5 0.4 0.079 12.5 0.2 1.4 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Chitin_synth_2 PF03142.10 KFX86379.1 - 6.1e-88 295.4 4.2 3.4e-87 293.0 3.2 1.7 2 0 0 2 2 2 1 Chitin synthase DEK_C PF08766.6 KFX86379.1 - 3.4e-17 61.9 0.1 2.9e-15 55.7 0.0 2.2 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 KFX86379.1 - 0.016 15.0 0.2 0.031 14.0 0.1 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KFX86379.1 - 0.27 10.9 9.7 1.1 8.9 6.7 1.9 1 1 0 1 1 1 0 Glycosyl transferase family group 2 DUF2592 PF10766.4 KFX86379.1 - 3.6 6.9 7.0 3.9 6.9 3.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2592) PB1 PF00564.19 KFX86380.1 - 1.3e-08 34.3 0.0 2.1e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 PB1 domain Pro-rich PF15240.1 KFX86381.1 - 0.12 12.4 34.1 0.15 12.1 23.6 1.3 1 0 0 1 1 1 0 Proline-rich ADH_zinc_N PF00107.21 KFX86384.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase GATA PF00320.22 KFX86388.1 - 0.0007 18.8 2.4 0.0007 18.8 1.7 2.7 3 0 0 3 3 3 2 GATA zinc finger YwqJ-deaminase PF14431.1 KFX86388.1 - 0.053 13.3 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 YwqJ-like deaminase Herpes_capsid PF06112.6 KFX86390.1 - 4.5 7.2 13.2 19 5.3 9.7 1.6 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein cNMP_binding PF00027.24 KFX86392.1 - 4.2e-31 106.6 0.0 3e-19 68.6 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain vATP-synt_E PF01991.13 KFX86397.1 - 1.7e-14 53.5 12.5 2.1e-14 53.2 8.6 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit NusB PF01029.13 KFX86397.1 - 0.019 14.9 1.0 0.021 14.7 0.7 1.1 1 0 0 1 1 1 0 NusB family DUF4122 PF13498.1 KFX86397.1 - 0.023 14.0 1.2 0.025 13.9 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4122) NMD3 PF04981.8 KFX86397.1 - 0.077 12.0 3.6 0.096 11.7 2.5 1.0 1 0 0 1 1 1 0 NMD3 family WASH-7_mid PF14744.1 KFX86397.1 - 0.098 11.4 0.9 0.1 11.3 0.6 1.1 1 0 0 1 1 1 0 WASH complex subunit 7 MRP-63 PF14978.1 KFX86397.1 - 0.38 11.2 2.6 0.47 10.9 1.8 1.1 1 0 0 1 1 1 0 Mitochondrial ribosome protein 63 LRR_1 PF00560.28 KFX86398.1 - 0.03 14.3 6.0 4.7 7.6 0.0 4.4 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 KFX86398.1 - 0.056 13.6 4.2 30 5.4 0.0 4.7 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 KFX86398.1 - 0.091 12.8 8.5 10 6.5 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich repeat LRR_8 PF13855.1 KFX86398.1 - 0.23 11.2 4.9 14 5.4 0.3 4.0 3 1 1 4 4 4 0 Leucine rich repeat LRR_4 PF12799.2 KFX86398.1 - 1.2 8.8 7.1 5.5 6.7 0.9 3.6 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) PS-DH PF14765.1 KFX86404.1 - 1.3e-17 63.8 0.0 2e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 KFX86404.1 - 1.4e-06 27.8 0.0 2.6e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 Acyl transferase domain S1 PF00575.18 KFX86405.1 - 1.6e-32 111.3 4.5 1.2e-12 47.6 0.0 4.3 4 0 0 4 4 4 4 S1 RNA binding domain Wyosine_form PF08608.7 KFX86407.1 - 8.4e-24 83.4 0.0 2.2e-23 82.0 0.0 1.8 2 0 0 2 2 2 1 Wyosine base formation Radical_SAM PF04055.16 KFX86407.1 - 3.6e-10 40.2 0.0 5.4e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily His_biosynth PF00977.16 KFX86408.1 - 1.3e-18 67.1 0.0 1.5e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein CDC50 PF03381.10 KFX86411.1 - 3.7e-90 301.8 0.0 4.4e-90 301.6 0.0 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Pol_alpha_B_N PF08418.5 KFX86416.1 - 5.6 6.4 8.1 9.6 5.6 5.7 1.4 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal vATP-synt_E PF01991.13 KFX86417.1 - 2.4e-42 144.4 1.3 2.7e-42 144.2 0.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit TPR_21 PF09976.4 KFX86417.1 - 0.022 14.7 1.8 0.2 11.6 0.2 2.1 1 1 0 2 2 2 0 Tetratricopeptide repeat PCP_red PF08369.5 KFX86419.1 - 0.0064 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Proto-chlorophyllide reductase 57 kD subunit DUF1488 PF07369.6 KFX86419.1 - 0.036 13.9 0.1 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) DUF3824 PF12868.2 KFX86423.1 - 0.002 19.0 1.4 0.0025 18.7 1.0 1.3 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) DAGAT PF03982.8 KFX86424.1 - 3.9e-88 294.9 0.0 4.8e-88 294.6 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase TMEM154 PF15102.1 KFX86426.1 - 0.0018 18.0 0.1 0.0026 17.4 0.1 1.2 1 0 0 1 1 1 1 TMEM154 protein family DUF1180 PF06679.7 KFX86426.1 - 0.0022 17.9 2.6 0.0032 17.3 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Plasmodium_Vir PF05795.6 KFX86426.1 - 0.0036 16.5 0.1 0.0041 16.3 0.1 1.2 1 0 0 1 1 1 1 Plasmodium vivax Vir protein Mucin PF01456.12 KFX86426.1 - 0.0076 16.0 9.5 0.012 15.4 6.6 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein Syndecan PF01034.15 KFX86426.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain DUF1517 PF07466.6 KFX86426.1 - 0.017 14.1 0.5 0.025 13.5 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Herpes_gE PF02480.11 KFX86426.1 - 0.067 11.4 0.3 0.1 10.8 0.2 1.3 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E MadL PF03817.8 KFX86426.1 - 0.076 12.8 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Malonate transporter MadL subunit MGC-24 PF05283.6 KFX86426.1 - 0.088 12.5 12.1 0.13 12.0 8.4 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Col_cuticle_N PF01484.12 KFX86426.1 - 0.19 11.4 0.4 1.7 8.4 0.1 2.1 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Beta-APP PF03494.8 KFX86426.1 - 1.1 8.7 3.9 1.9 8.0 2.7 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) SKG6 PF08693.5 KFX86426.1 - 3.1 7.1 6.5 0.14 11.4 0.7 1.6 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DNA_pol_E_B PF04042.11 KFX86429.1 - 5.8e-05 22.4 0.0 6.3e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF4246 PF14033.1 KFX86432.1 - 8.6e-85 285.2 0.0 9.8e-85 285.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) DUF3484 PF11983.3 KFX86437.1 - 0.19 12.5 3.2 0.26 12.1 2.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3484) FAP PF07174.6 KFX86437.1 - 0.76 9.0 17.4 0.79 8.9 12.0 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) HLH PF00010.21 KFX86439.1 - 7.1e-16 57.6 0.0 1.2e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GAS PF13851.1 KFX86439.1 - 0.033 13.3 0.3 0.056 12.6 0.2 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Smac_DIABLO PF09057.5 KFX86439.1 - 0.07 12.2 3.7 0.098 11.7 2.6 1.2 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases ISG65-75 PF11727.3 KFX86439.1 - 0.076 12.0 3.0 0.091 11.7 2.1 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF904 PF06005.7 KFX86439.1 - 0.22 11.8 2.3 0.68 10.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Nucleoporin_N PF08801.6 KFX86440.1 - 4.1e-24 85.1 0.0 4.9e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like F-box PF00646.28 KFX86441.1 - 3.2e-06 26.6 1.3 0.00013 21.5 0.5 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KFX86441.1 - 0.0013 18.4 1.5 0.0037 16.9 0.1 2.4 3 0 0 3 3 3 1 F-box-like LRR_6 PF13516.1 KFX86441.1 - 0.0049 16.8 0.1 4.2 7.7 0.0 2.7 2 0 0 2 2 2 2 Leucine Rich repeat LRR_1 PF00560.28 KFX86441.1 - 0.035 14.1 1.0 6.2 7.2 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich Repeat adh_short PF00106.20 KFX86443.1 - 9.1e-18 64.7 0.0 1e-17 64.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX86443.1 - 7.7e-09 35.4 0.0 1e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFX86443.1 - 2.5e-07 30.7 0.0 2.9e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 KFX86443.1 - 0.00023 20.9 0.1 0.00082 19.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KFX86443.1 - 0.0073 15.7 0.0 0.0092 15.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Membr_traf_MHD PF10540.4 KFX86444.1 - 4.5e-23 81.5 0.3 9.3e-23 80.5 0.2 1.5 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain K_channel_TID PF07941.6 KFX86444.1 - 3.7 7.8 8.1 1 9.6 2.1 2.1 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Lyase_1 PF00206.15 KFX86446.1 - 4.5e-35 121.3 0.1 6.3e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 KFX86446.1 - 2.3e-23 82.0 0.0 4e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Fumarase C C-terminus IglC PF11550.3 KFX86446.1 - 0.12 11.6 0.0 0.64 9.2 0.0 1.9 2 0 0 2 2 2 0 Intracellular growth locus C protein G-alpha PF00503.15 KFX86446.1 - 0.13 10.8 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit zf-CCCH PF00642.19 KFX86447.1 - 2.8e-07 30.0 2.2 2.8e-07 30.0 1.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 KFX86447.1 - 6e-05 22.8 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFX86447.1 - 0.003 17.1 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-SAP30 PF13866.1 KFX86447.1 - 0.064 12.9 0.9 0.54 9.9 0.2 2.2 2 0 0 2 2 2 0 SAP30 zinc-finger SCRG1 PF15224.1 KFX86447.1 - 1.2 8.9 5.2 2.9 7.7 0.3 2.4 2 0 0 2 2 2 0 Scrapie-responsive protein 1 DUF3779 PF12621.3 KFX86449.1 - 4.5e-15 55.3 0.0 5e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Phosphate metabolism protein V-SNARE_C PF12352.3 KFX86459.1 - 2e-15 56.5 5.0 5.9e-15 55.0 0.2 2.3 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus NIT PF08376.5 KFX86459.1 - 0.27 10.7 4.5 0.18 11.2 0.5 1.9 2 0 0 2 2 2 0 Nitrate and nitrite sensing DIOX_N PF14226.1 KFX86460.1 - 4.6e-06 27.1 0.0 2.5e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Thaumatin PF00314.12 KFX86463.1 - 2.7e-40 138.1 0.4 3.2e-40 137.8 0.3 1.1 1 0 0 1 1 1 1 Thaumatin family MFS_1 PF07690.11 KFX86472.1 - 6.5e-21 74.4 5.8 7.8e-21 74.1 4.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX86472.1 - 8.4e-11 41.0 2.7 1.1e-10 40.7 1.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 KFX86472.1 - 2.5e-05 22.8 4.0 3.6e-05 22.3 1.2 1.9 1 1 1 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.8 KFX86472.1 - 0.026 12.7 2.5 0.033 12.3 1.7 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.11 KFX86472.1 - 0.18 10.4 1.2 7.8 5.0 0.6 2.6 1 1 1 2 2 2 0 BT1 family MFS_3 PF05977.8 KFX86472.1 - 1.7 6.6 5.6 0.9 7.5 0.9 1.9 1 1 0 2 2 2 0 Transmembrane secretion effector Trehalase PF01204.13 KFX86475.1 - 2.6e-79 267.2 0.1 2.9e-79 267.0 0.1 1.0 1 0 0 1 1 1 1 Trehalase SH3_9 PF14604.1 KFX86475.1 - 0.083 12.4 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Spc97_Spc98 PF04130.8 KFX86476.1 - 9.3e-19 67.1 0.0 1e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Spc97 / Spc98 family Zn_clus PF00172.13 KFX86477.1 - 1.4e-05 24.8 7.7 2.2e-05 24.2 5.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX86477.1 - 0.063 12.1 0.8 0.09 11.6 0.5 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Tropomyosin_1 PF12718.2 KFX86478.1 - 0.0036 17.1 3.6 0.0047 16.7 2.5 1.1 1 0 0 1 1 1 1 Tropomyosin like DUF4570 PF15134.1 KFX86478.1 - 0.0049 16.7 0.8 0.0085 15.9 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4570) HrpA_pilin PF09589.5 KFX86478.1 - 0.08 13.3 0.4 0.091 13.1 0.3 1.2 1 0 0 1 1 1 0 HrpA pilus formation protein DUF4140 PF13600.1 KFX86478.1 - 0.15 12.5 1.9 0.23 11.9 1.3 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 KFX86478.1 - 0.17 11.4 1.7 0.22 11.1 1.2 1.1 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 KFX86478.1 - 0.17 11.3 3.9 0.23 10.9 2.7 1.2 1 0 0 1 1 1 0 Septum formation initiator RRM_1 PF00076.17 KFX86479.1 - 2e-16 59.3 0.0 9.2e-13 47.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX86479.1 - 2.3e-09 37.0 0.0 2.1e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX86479.1 - 1.1e-08 34.7 0.0 0.00018 21.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ku PF02735.11 KFX86481.1 - 9.9e-24 83.8 0.0 1.2e-23 83.5 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain CCER1 PF15482.1 KFX86483.1 - 0.0039 16.8 2.6 0.12 12.0 0.2 2.1 2 0 0 2 2 2 2 Coiled-coil domain-containing glutamate-rich protein family 1 Glycophorin_A PF01102.13 KFX86483.1 - 0.0059 16.3 0.1 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Glycophorin A G_glu_transpept PF01019.16 KFX86484.1 - 1.1e-71 241.8 0.0 1.3e-71 241.6 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Methyltransf_11 PF08241.7 KFX86485.1 - 0.00034 21.0 0.0 0.00064 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ligase_CoA PF00549.14 KFX86486.1 - 3.1e-12 46.3 0.0 4.4e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 CoA-ligase Citrate_synt PF00285.16 KFX86486.1 - 5.1e-06 25.4 0.2 0.0014 17.4 0.2 2.2 1 1 1 2 2 2 2 Citrate synthase P22_AR_C PF10548.4 KFX86486.1 - 0.079 12.8 0.0 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 P22AR C-terminal domain Sec63 PF02889.11 KFX86491.1 - 1.3e-57 195.4 0.1 1.7e-57 195.0 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DUF3945 PF13101.1 KFX86491.1 - 0.081 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3945) ABC_tran PF00005.22 KFX86500.1 - 1.3e-06 28.7 0.0 2.6e-06 27.7 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 KFX86500.1 - 0.0005 20.1 0.0 0.00062 19.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Pepsin-I3 PF06394.8 KFX86500.1 - 0.0069 16.0 0.0 0.0098 15.5 0.0 1.2 1 0 0 1 1 1 1 Pepsin inhibitor-3-like repeated domain SbcCD_C PF13558.1 KFX86500.1 - 0.013 15.4 0.2 0.078 12.9 0.1 2.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 KFX86500.1 - 0.055 12.6 0.0 0.065 12.4 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Oxysterol_BP PF01237.13 KFX86503.1 - 1.8e-28 99.0 0.0 1.2e-27 96.3 0.0 1.9 1 1 0 1 1 1 1 Oxysterol-binding protein Zn_clus PF00172.13 KFX86511.1 - 5.3e-08 32.6 9.1 8.7e-08 31.9 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myf5 PF12232.3 KFX86511.1 - 4.4 7.9 9.4 2.8 8.5 0.1 3.5 3 1 1 4 4 4 0 Myogenic determination factor 5 zf-RING_2 PF13639.1 KFX86515.1 - 1e-09 38.0 1.3 1.4e-09 37.5 0.9 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFX86515.1 - 4.4e-05 23.5 0.1 7.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFX86515.1 - 6.2e-05 22.9 1.2 8.8e-05 22.4 0.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFX86515.1 - 0.0002 21.1 0.6 0.00029 20.6 0.4 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 KFX86515.1 - 0.00069 19.2 0.0 0.00096 18.7 0.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX86515.1 - 0.032 13.8 0.4 0.049 13.2 0.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 KFX86515.1 - 0.25 10.8 1.5 0.37 10.3 0.0 2.0 3 0 0 3 3 3 0 Rad50 zinc hook motif SOG2 PF10428.4 KFX86518.1 - 0.11 11.1 0.8 0.14 10.7 0.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Pirin_C PF05726.8 KFX86519.1 - 2e-23 82.4 0.0 3e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 Pirin C-terminal cupin domain NDK PF00334.14 KFX86521.1 - 8.7e-18 64.4 0.0 1e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Cpn60_TCP1 PF00118.19 KFX86523.1 - 1.9e-19 69.6 0.0 2.1e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sec7 PF01369.15 KFX86525.1 - 2.4e-32 112.1 0.1 3.4e-32 111.6 0.1 1.2 1 0 0 1 1 1 1 Sec7 domain AMP-binding PF00501.23 KFX86528.1 - 4.8e-25 87.8 0.0 5.8e-25 87.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme Ank_2 PF12796.2 KFX86530.1 - 8.2e-36 122.2 0.0 5.9e-17 61.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFX86530.1 - 4.5e-34 114.5 0.0 5.6e-08 32.2 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 KFX86530.1 - 7.8e-25 84.4 0.0 1.3e-06 28.0 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KFX86530.1 - 2.4e-20 72.4 0.0 1.1e-08 35.3 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX86530.1 - 1.9e-16 59.7 0.0 0.00016 21.7 0.0 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) UBA PF00627.26 KFX86530.1 - 0.025 14.3 0.2 75 3.3 0.0 4.1 4 0 0 4 4 4 0 UBA/TS-N domain DUF498 PF04430.9 KFX86530.1 - 0.026 14.0 0.0 0.95 9.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) IPK PF03770.11 KFX86536.1 - 2e-39 135.3 0.0 2.3e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Inositol polyphosphate kinase polyprenyl_synt PF00348.12 KFX86541.1 - 2.1e-34 118.5 0.0 4.2e-34 117.5 0.0 1.5 1 1 0 1 1 1 1 Polyprenyl synthetase Aldo_ket_red PF00248.16 KFX86545.1 - 3.4e-26 91.7 0.1 3.9e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family YL1 PF05764.8 KFX86547.1 - 3.1e-28 99.0 9.2 3.6e-28 98.7 6.4 1.0 1 0 0 1 1 1 1 YL1 nuclear protein RhoGAP PF00620.22 KFX86550.1 - 2.4e-39 134.4 0.0 3.2e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain FAP PF07174.6 KFX86551.1 - 1.5 8.0 26.6 1.8 7.8 18.4 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Terpene_synth_C PF03936.11 KFX86557.1 - 3.3e-06 26.5 0.1 4.1e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TAFII28 PF04719.9 KFX86559.1 - 3.5e-20 71.5 0.0 1.6e-19 69.5 0.0 1.8 2 0 0 2 2 2 1 hTAFII28-like protein conserved region 2OG-FeII_Oxy PF03171.15 KFX86560.1 - 3.5e-12 46.4 0.0 6e-12 45.7 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Lycopene_cycl PF05834.7 KFX86562.1 - 0.096 11.5 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Arb2 PF09757.4 KFX86563.1 - 3.6e-16 59.1 0.0 4.5e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Arb2 domain Cu-oxidase_2 PF07731.9 KFX86569.1 - 6.8e-14 51.5 0.3 1.2e-13 50.6 0.2 1.4 1 0 0 1 1 1 1 Multicopper oxidase BCS1_N PF08740.6 KFX86571.1 - 1.6e-24 86.5 0.0 1.9e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 BCS1 N terminal Pkinase PF00069.20 KFX86577.1 - 8.1e-11 41.5 0.0 9.1e-11 41.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX86577.1 - 3.5e-10 39.4 0.0 3.9e-10 39.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Dabb PF07876.7 KFX86577.1 - 0.091 13.2 0.0 0.16 12.4 0.0 1.4 1 1 0 1 1 1 0 Stress responsive A/B Barrel Domain Ferric_reduct PF01794.14 KFX86580.1 - 1.3e-11 44.7 1.6 1.4e-11 44.5 1.1 1.2 1 0 0 1 1 1 1 Ferric reductase like transmembrane component Methyltransf_11 PF08241.7 KFX86581.1 - 1.4e-12 47.9 0.0 2.3e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX86581.1 - 4.2e-05 23.3 0.0 6e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX86581.1 - 0.00042 20.7 0.0 0.00081 19.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX86581.1 - 0.026 14.5 0.0 0.038 14.0 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KFX86581.1 - 0.037 12.9 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.13 KFX86581.1 - 0.051 12.6 0.0 0.098 11.7 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KFX86581.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KFX86581.1 - 0.12 12.7 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PAPA-1 PF04795.7 KFX86582.1 - 1.6e-10 41.5 0.0 1.9e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 PAPA-1-like conserved region Homeobox_KN PF05920.6 KFX86584.1 - 1.1e-19 69.8 0.1 2e-19 68.9 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFX86584.1 - 3.2e-08 33.0 0.3 4.5e-08 32.5 0.2 1.2 1 0 0 1 1 1 1 Homeobox domain Pyridoxal_deC PF00282.14 KFX86585.1 - 2.4e-13 49.2 0.0 2.8e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cofilin_ADF PF00241.15 KFX86588.1 - 3.3e-07 30.2 0.0 3.8e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF4511 PF14974.1 KFX86590.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4511) DUF4042 PF13251.1 KFX86591.1 - 0.032 13.7 0.3 0.046 13.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) zf-RING_2 PF13639.1 KFX86592.1 - 3.8e-13 49.0 7.2 5.8e-13 48.4 5.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFX86592.1 - 3.3e-08 33.0 4.6 5e-08 32.4 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFX86592.1 - 2.3e-07 30.7 5.0 4.7e-07 29.8 3.5 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KFX86592.1 - 1e-06 28.3 4.2 1.5e-06 27.8 2.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFX86592.1 - 1.9e-05 24.5 6.5 3e-05 23.9 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFX86592.1 - 6.3e-05 22.5 2.9 9.1e-05 22.0 2.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFX86592.1 - 0.00044 20.0 3.4 0.0013 18.5 2.3 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KFX86592.1 - 0.0031 17.0 5.7 0.005 16.3 4.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 KFX86592.1 - 0.015 15.0 1.3 0.022 14.4 0.4 1.7 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFX86592.1 - 0.045 13.6 5.9 0.093 12.6 4.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.24 KFX86592.1 - 0.064 12.9 5.0 0.12 12.1 3.4 1.5 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.2 KFX86592.1 - 0.071 13.1 4.4 0.15 12.1 3.1 1.6 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 KFX86592.1 - 0.13 12.1 5.3 0.5 10.3 3.6 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 KFX86592.1 - 2 8.2 7.6 0.31 10.7 0.6 2.1 1 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 KFX86592.1 - 2.1 8.4 5.3 3.5 7.6 3.7 1.4 1 0 0 1 1 1 0 RING-like domain EVE PF01878.13 KFX86595.1 - 1.5e-15 57.4 0.1 1.7e-15 57.2 0.1 1.1 1 0 0 1 1 1 1 EVE domain DUF3473 PF11959.3 KFX86595.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3473) DivIC PF04977.10 KFX86605.1 - 0.00039 19.8 0.8 0.00039 19.8 0.5 2.8 2 1 1 3 3 3 1 Septum formation initiator Reo_sigmaC PF04582.7 KFX86605.1 - 0.001 18.3 0.4 0.0016 17.7 0.3 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Bacillus_HBL PF05791.6 KFX86605.1 - 0.0029 16.9 0.5 0.0052 16.1 0.4 1.4 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) SseC PF04888.7 KFX86605.1 - 0.0032 16.8 1.8 0.0035 16.7 1.3 1.1 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family Med4 PF10018.4 KFX86605.1 - 0.004 16.5 0.5 0.004 16.5 0.3 2.1 2 1 0 2 2 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Syntaxin PF00804.20 KFX86605.1 - 0.0058 16.7 1.6 0.0058 16.7 1.1 1.9 2 0 0 2 2 2 1 Syntaxin Seryl_tRNA_N PF02403.17 KFX86605.1 - 0.0076 16.2 1.0 0.0076 16.2 0.7 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain TBPIP PF07106.8 KFX86605.1 - 0.015 14.8 0.8 0.015 14.8 0.5 1.7 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1319 PF07028.6 KFX86605.1 - 0.02 15.0 0.7 0.037 14.2 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) DUF641 PF04859.7 KFX86605.1 - 0.023 14.4 0.3 0.023 14.4 0.2 1.8 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Striatin PF08232.7 KFX86605.1 - 0.026 14.8 3.1 0.53 10.5 0.1 2.2 2 0 0 2 2 2 0 Striatin family ATG16 PF08614.6 KFX86605.1 - 0.028 14.2 0.2 0.028 14.2 0.2 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 KFX86605.1 - 0.054 13.3 0.7 0.054 13.3 0.5 2.1 2 1 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Herpes_U30 PF04523.8 KFX86605.1 - 0.056 10.8 0.3 0.057 10.8 0.2 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 DUF1192 PF06698.6 KFX86605.1 - 0.067 13.0 2.6 3.4 7.5 0.4 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) COMP PF11598.3 KFX86605.1 - 0.067 13.2 0.2 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Cep57_MT_bd PF06657.8 KFX86605.1 - 0.073 13.0 0.4 0.37 10.7 0.1 2.3 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 IncA PF04156.9 KFX86605.1 - 0.079 12.5 4.4 0.053 13.1 1.8 1.6 1 1 0 1 1 1 0 IncA protein Ribosomal_L29 PF00831.18 KFX86605.1 - 0.082 12.6 0.2 3.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Ribosomal L29 protein USP8_interact PF08941.5 KFX86605.1 - 0.087 12.1 0.2 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 USP8 interacting DUF4618 PF15397.1 KFX86605.1 - 0.098 11.9 0.2 0.098 11.9 0.1 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) gpW PF02831.10 KFX86605.1 - 0.1 12.1 1.0 10 5.7 0.0 3.0 1 1 2 3 3 3 0 gpW DUF4549 PF15082.1 KFX86605.1 - 0.12 12.0 0.7 1.2 8.7 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4549) Cluap1 PF10234.4 KFX86605.1 - 0.13 11.4 4.3 0.2 10.8 2.9 1.5 1 1 0 1 1 1 0 Clusterin-associated protein-1 DUF4140 PF13600.1 KFX86605.1 - 0.13 12.7 0.1 0.13 12.7 0.1 2.4 3 1 0 3 3 2 0 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 KFX86605.1 - 0.19 12.0 0.1 0.19 12.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Baculo_PEP_C PF04513.7 KFX86605.1 - 0.22 11.3 6.6 0.043 13.6 2.0 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AT_hook PF02178.14 KFX86605.1 - 0.24 11.1 0.3 0.24 11.1 0.2 2.0 2 0 0 2 2 1 0 AT hook motif Atg14 PF10186.4 KFX86605.1 - 0.26 10.1 4.9 0.35 9.7 3.2 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DASH_Spc34 PF08657.5 KFX86605.1 - 0.28 10.7 7.1 0.12 11.9 0.4 2.5 2 1 1 3 3 3 0 DASH complex subunit Spc34 Phage_GP20 PF06810.6 KFX86605.1 - 0.37 10.2 5.0 0.05 13.0 0.5 1.7 2 0 0 2 2 2 0 Phage minor structural protein GP20 Bap31 PF05529.7 KFX86605.1 - 0.59 9.5 4.9 0.32 10.4 0.1 2.1 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF2203 PF09969.4 KFX86605.1 - 0.6 10.3 5.5 0.53 10.5 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Mnd1 PF03962.10 KFX86605.1 - 0.69 9.5 5.6 0.67 9.5 0.1 2.2 2 0 0 2 2 2 0 Mnd1 family FlaC_arch PF05377.6 KFX86605.1 - 0.77 9.6 3.4 1.9 8.4 0.6 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) ADIP PF11559.3 KFX86605.1 - 1.1 9.1 7.3 0.099 12.5 0.6 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 KFX86605.1 - 1.3 7.6 7.1 0.036 12.7 0.6 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein Med9 PF07544.8 KFX86605.1 - 2.1 8.1 5.4 0.45 10.2 0.5 2.1 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Syntaxin_2 PF14523.1 KFX86605.1 - 2.6 8.1 7.0 0.31 11.0 1.4 1.9 2 0 0 2 2 2 0 Syntaxin-like protein UBN2 PF14223.1 KFX86606.1 - 0.063 13.0 0.0 0.085 12.6 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Pkinase PF00069.20 KFX86608.1 - 4e-39 134.3 0.0 5.1e-39 133.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX86608.1 - 1e-26 93.5 0.0 1.4e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX86608.1 - 1.7e-06 27.1 0.0 2.1e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KFX86608.1 - 0.023 13.5 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3043 PF11241.3 KFX86616.1 - 0.081 12.5 2.6 1.3 8.6 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Apis_Csd PF11671.3 KFX86616.1 - 7.2 6.3 6.9 15 5.3 4.8 1.5 1 0 0 1 1 1 0 Complementary sex determiner protein CBM_1 PF00734.13 KFX86724.1 - 1.9e-14 53.0 12.3 5.1e-14 51.6 8.6 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KFX86724.1 - 0.16 11.9 2.7 0.29 11.2 1.8 1.4 1 0 0 1 1 1 0 Toxin 7 ABC_tran PF00005.22 KFX86768.1 - 6.3e-13 49.2 0.0 7e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 ABC transporter Secretin_N PF03958.12 KFX86783.1 - 0.028 14.6 0.9 0.04 14.1 0.1 1.7 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain DLIC PF05783.6 KFX86783.1 - 2.9 6.4 7.4 3.2 6.3 5.1 1.0 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) p450 PF00067.17 KFX86931.1 - 1.7e-26 92.7 0.0 1.9e-26 92.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MCPVI PF02993.9 KFX86975.1 - 0.92 9.6 4.8 1.4 9.0 3.3 1.3 1 0 0 1 1 1 0 Minor capsid protein VI tRNA-synt_2 PF00152.15 KFX87015.1 - 7.1e-15 54.6 0.2 7.4e-15 54.5 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) Cyt-b5 PF00173.23 KFX87015.1 - 0.0048 16.6 0.0 0.0056 16.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PDCD2_C PF04194.8 KFX87145.1 - 2.1e-31 108.7 0.0 2.3e-31 108.6 0.0 1.0 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain DUF3113 PF11310.3 KFX87145.1 - 0.033 13.8 0.1 0.05 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) WD40 PF00400.27 KFX87164.1 - 2.2e-10 40.0 0.2 9.9e-09 34.7 0.0 2.8 3 0 0 3 3 3 1 WD domain, G-beta repeat BNR_3 PF13859.1 KFX87219.1 - 0.15 11.1 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 BNR repeat-like domain O-FucT PF10250.4 KFX87234.1 - 0.023 13.8 0.1 0.45 9.5 0.1 2.0 1 1 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Daxx PF03344.10 KFX87253.1 - 6.9 5.0 10.8 8.1 4.7 7.5 1.1 1 0 0 1 1 1 0 Daxx Family DUF89 PF01937.14 KFX87279.1 - 3.3e-38 131.3 0.0 3.8e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 zf-FPG_IleRS PF06827.9 KFX87309.1 - 0.021 14.4 0.9 1.5 8.5 0.0 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS SMN PF06003.7 KFX87309.1 - 0.2 10.7 1.3 0.79 8.7 0.5 2.0 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) DAO PF01266.19 KFX87317.1 - 3.1e-60 204.0 1.6 3.1e-60 204.0 1.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX87317.1 - 3.5e-06 26.9 0.3 8.5e-06 25.7 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KFX87317.1 - 2.3e-05 24.2 3.5 0.00013 21.7 0.0 3.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KFX87317.1 - 3.5e-05 23.9 0.4 0.32 11.0 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFX87317.1 - 0.00017 20.6 0.4 0.00095 18.1 0.1 2.2 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.12 KFX87317.1 - 0.00063 18.9 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KFX87317.1 - 0.003 17.4 0.1 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFX87317.1 - 0.0051 15.7 1.0 0.0089 14.9 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KFX87317.1 - 0.0057 15.1 0.0 1.4 7.2 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein K_oxygenase PF13434.1 KFX87317.1 - 0.035 13.0 1.2 0.04 12.8 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 KFX87317.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FNIP_N PF14636.1 KFX87319.1 - 6.2e-21 75.2 3.6 1.4e-20 74.0 0.0 3.0 3 0 0 3 3 3 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 KFX87319.1 - 0.028 13.9 0.1 0.26 10.8 0.0 2.3 2 1 1 3 3 3 0 Folliculin-interacting protein middle domain Pneumo_att_G PF05539.6 KFX87319.1 - 2.2 7.5 6.1 5.7 6.2 4.3 1.6 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G IF-2B PF01008.12 KFX87320.1 - 1.7e-47 161.7 0.0 1.9e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.17 KFX87320.1 - 0.0022 17.6 0.0 2.6 7.6 0.0 2.4 2 0 0 2 2 2 2 DeoR C terminal sensor domain Rib_5-P_isom_A PF06026.9 KFX87320.1 - 0.0047 16.2 0.3 0.27 10.5 0.0 2.2 1 1 1 2 2 2 2 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Anoctamin PF04547.7 KFX87322.1 - 7.5e-121 403.9 6.0 8.9e-121 403.6 4.1 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Aldedh PF00171.17 KFX87326.1 - 5.7e-107 357.9 0.1 7.4e-107 357.5 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Homeobox PF00046.24 KFX87327.1 - 2.2e-13 49.5 1.4 4.9e-13 48.4 0.9 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFX87327.1 - 0.032 13.9 0.1 0.079 12.6 0.0 1.7 1 0 0 1 1 1 0 Homeobox KN domain Glyco_tranf_2_3 PF13641.1 KFX87338.1 - 8.3e-22 78.1 0.1 2e-21 76.8 0.1 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KFX87338.1 - 4.6e-08 32.5 0.3 2.4e-07 30.2 0.2 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KFX87338.1 - 1.1e-07 31.7 0.0 5.8e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 WD40 PF00400.27 KFX87362.1 - 2.3e-46 154.0 24.8 6.8e-09 35.2 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KFX87362.1 - 0.0014 18.3 0.0 0.83 9.3 0.0 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A MBOAT PF03062.14 KFX87363.1 - 1.7e-21 76.7 13.8 2.7e-21 76.0 9.5 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KFX87363.1 - 0.0029 17.6 1.4 0.0087 16.1 1.0 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Pox_I5 PF04713.7 KFX87363.1 - 0.008 15.8 1.4 0.018 14.7 0.1 2.2 2 0 0 2 2 2 1 Poxvirus protein I5 ICMT PF04140.9 KFX87364.1 - 7.2e-26 90.2 0.0 1.3e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KFX87364.1 - 7.5e-14 51.7 1.4 7.5e-14 51.7 1.0 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 KFX87364.1 - 0.00059 19.1 0.2 0.00089 18.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.6 KFX87364.1 - 0.012 15.0 4.1 0.02 14.2 2.8 1.5 1 1 0 1 1 1 0 NnrU protein DUF3816 PF12822.2 KFX87364.1 - 0.032 14.1 1.4 1.2 9.0 1.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) RPAP1_N PF08621.5 KFX87374.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 RPAP1-like, N-terminal SH3_1 PF00018.23 KFX87376.1 - 3e-11 42.5 0.1 4.6e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFX87376.1 - 3.6e-10 39.2 0.1 5.3e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFX87376.1 - 1.7e-07 30.5 0.0 3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Pex14_N PF04695.8 KFX87376.1 - 0.091 12.8 9.4 0.21 11.6 1.5 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2076 PF09849.4 KFX87376.1 - 0.16 11.9 5.1 0.089 12.8 0.9 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Mito_fiss_reg PF05308.6 KFX87376.1 - 2.9 7.1 10.2 0.29 10.4 2.0 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF202 PF02656.10 KFX87377.1 - 2.4e-25 88.5 1.2 2.4e-25 88.5 0.9 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Herpes_UL37_2 PF07413.6 KFX87377.1 - 0.034 12.9 0.4 3.1 6.5 0.0 2.1 2 0 0 2 2 2 0 Betaherpesvirus immediate-early glycoprotein UL37 DUF1509 PF07420.6 KFX87377.1 - 3.5 6.8 9.7 5.6 6.1 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Transformer PF06495.6 KFX87377.1 - 7.2 6.4 10.0 10 5.9 6.9 1.2 1 0 0 1 1 1 0 Fruit fly transformer protein PLU-1 PF08429.6 KFX87388.1 - 4.3e-96 321.7 14.8 3.9e-94 315.2 9.5 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 KFX87388.1 - 3.1e-43 146.6 0.2 7.2e-43 145.4 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 KFX87388.1 - 3.8e-28 97.1 0.0 2.9e-27 94.3 0.0 2.4 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 KFX87388.1 - 8.8e-18 63.7 32.8 8.2e-09 35.0 4.9 3.7 3 0 0 3 3 3 3 PHD-finger zf-C5HC2 PF02928.11 KFX87388.1 - 7.2e-14 51.5 6.9 1.8e-13 50.3 4.8 1.7 1 0 0 1 1 1 1 C5HC2 zinc finger JmjN PF02375.12 KFX87388.1 - 3.1e-11 42.6 1.9 7.1e-11 41.4 1.3 1.7 1 0 0 1 1 1 1 jmjN domain zf-PHD-like PF15446.1 KFX87388.1 - 0.19 10.9 9.0 1.4 8.1 1.3 2.6 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zinc_ribbon_5 PF13719.1 KFX87388.1 - 1.9 8.1 11.6 0.1 12.1 0.7 3.6 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_2 PF13639.1 KFX87388.1 - 5.5 6.9 21.8 4.1 7.3 4.1 2.6 2 0 0 2 2 2 0 Ring finger domain DnaJ PF00226.26 KFX87391.1 - 6.5e-15 54.6 0.2 1e-14 54.0 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Mem_trans PF03547.13 KFX87394.1 - 3.5e-51 173.6 0.1 6.2e-51 172.8 0.1 1.4 1 1 0 1 1 1 1 Membrane transport protein ELFV_dehydrog PF00208.16 KFX87395.1 - 6.2e-56 189.7 0.0 1.1e-55 188.9 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 KFX87395.1 - 3.1e-19 68.0 0.0 3.8e-15 54.4 0.0 2.5 2 1 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 KFX87395.1 - 0.021 14.3 0.0 0.056 13.0 0.0 1.6 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain HLH PF00010.21 KFX87396.1 - 1.5e-11 43.7 0.0 4.6e-11 42.2 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Zn_clus PF00172.13 KFX87428.1 - 0.0023 17.8 8.9 0.0053 16.6 6.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bul1_C PF04426.7 KFX87428.1 - 0.083 12.0 0.1 0.24 10.5 0.1 1.7 1 0 0 1 1 1 0 Bul1 C terminus DUF221 PF02714.10 KFX87429.1 - 2.3e-40 138.4 8.6 2.3e-40 138.4 6.0 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF221 DUF3779 PF12621.3 KFX87429.1 - 2.9e-17 62.3 0.0 4.6e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Phosphate metabolism protein DUF2244 PF10003.4 KFX87429.1 - 1.1 8.6 3.9 0.67 9.3 0.4 2.2 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Zn_clus PF00172.13 KFX87438.1 - 5.1e-07 29.4 13.6 8.1e-07 28.8 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 KFX87438.1 - 0.21 9.8 20.7 0.3 9.2 14.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cation_ATPase_C PF00689.16 KFX87447.1 - 9.7e-34 116.4 5.8 9.7e-34 116.4 4.0 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus PP2C PF00481.16 KFX87447.1 - 1.7e-31 109.5 0.0 2.8e-26 92.4 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C E1-E2_ATPase PF00122.15 KFX87447.1 - 3.1e-25 88.5 2.8 4.2e-25 88.1 0.7 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KFX87447.1 - 1.7e-18 67.8 0.0 8.2e-13 49.2 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFX87447.1 - 1e-15 57.4 0.0 2e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFX87447.1 - 1.2e-10 41.8 0.0 6e-09 36.3 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFX87447.1 - 0.00091 18.8 0.1 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PP2C_2 PF13672.1 KFX87447.1 - 0.036 13.4 0.0 0.086 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein phosphatase 2C DUF2231 PF09990.4 KFX87447.1 - 0.04 14.2 2.9 0.056 13.7 0.5 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) zf-C2H2 PF00096.21 KFX87452.1 - 3.6e-08 33.2 9.7 0.00046 20.3 2.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX87452.1 - 1.2e-07 31.5 10.3 0.00056 20.0 3.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFX87452.1 - 2.4e-06 27.5 17.6 6.5e-06 26.1 2.7 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFX87452.1 - 0.03 14.2 0.9 3.4 7.7 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFX87452.1 - 0.39 10.9 5.7 2.9 8.1 0.4 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 KFX87452.1 - 0.64 9.7 5.6 8.6 6.1 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF3710 PF12502.3 KFX87459.1 - 0.094 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3710) Methyltransf_16 PF10294.4 KFX87459.1 - 0.12 11.7 0.0 3.8 6.9 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase RNA_pol_Rbc25 PF08292.7 KFX87460.1 - 7.3e-28 97.2 0.0 1.1e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KFX87460.1 - 1.9e-15 56.7 0.0 3.1e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 NUFIP1 PF10453.4 KFX87461.1 - 3.5e-09 36.0 1.7 3.5e-09 36.0 1.2 2.6 4 0 0 4 4 4 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 KFX87461.1 - 0.17 11.5 6.3 0.29 10.8 4.4 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Rotamase PF00639.16 KFX87461.1 - 1.2 9.9 9.3 16 6.3 0.0 3.3 2 1 0 2 2 2 0 PPIC-type PPIASE domain Glyco_hydro_17 PF00332.13 KFX87467.1 - 4.9e-07 29.0 0.9 0.0025 16.8 0.1 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 ETRAMP PF09716.5 KFX87467.1 - 0.02 14.8 0.1 0.02 14.8 0.0 2.1 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Trep_Strep PF09605.5 KFX87467.1 - 0.17 11.5 0.2 0.27 10.8 0.2 1.2 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) UIM PF02809.15 KFX87470.1 - 0.1 12.2 0.5 0.1 12.2 0.3 3.8 4 0 0 4 4 4 0 Ubiquitin interaction motif Sugar_tr PF00083.19 KFX87472.1 - 1.5e-74 251.2 19.7 1.8e-74 250.9 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX87472.1 - 1.1e-33 116.4 48.7 3e-31 108.4 17.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX87472.1 - 5.9e-08 31.5 19.5 3e-07 29.2 0.2 3.2 3 1 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 KFX87472.1 - 5.4e-06 24.8 0.9 5.4e-06 24.8 0.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF554 PF04474.7 KFX87472.1 - 0.00055 19.1 0.7 0.0023 17.1 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF554) MFS_1 PF07690.11 KFX87473.1 - 7.5e-34 116.9 72.6 6.2e-30 104.0 37.6 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Epimerase PF01370.16 KFX87474.1 - 2.4e-14 53.3 0.4 1.3e-13 50.9 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX87474.1 - 2.9e-14 53.4 0.2 5.3e-14 52.6 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFX87474.1 - 2e-11 43.1 0.0 2.6e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KFX87474.1 - 1.8e-06 27.9 0.5 4.2e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KFX87474.1 - 1.4e-05 24.1 0.0 2.5e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KFX87474.1 - 4.1e-05 22.9 0.0 8e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 KFX87474.1 - 0.0062 15.4 0.0 0.0082 15.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KFX87474.1 - 0.0085 15.7 0.4 0.061 12.9 0.3 2.1 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 KFX87474.1 - 0.027 13.3 0.1 0.51 9.1 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain Fungal_trans PF04082.13 KFX87475.1 - 3.6e-14 52.2 0.0 7.1e-14 51.3 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_61 PF03443.9 KFX87476.1 - 1.9e-43 148.8 0.0 2.4e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.9 KFX87477.1 - 4.9e-54 183.4 0.4 5.5e-54 183.2 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HpaB PF03241.8 KFX87477.1 - 0.084 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase C terminal Epimerase PF01370.16 KFX87478.1 - 5e-11 42.4 0.1 8.3e-10 38.4 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KFX87478.1 - 2.6e-07 30.1 0.7 4.4e-07 29.3 0.5 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX87478.1 - 2.4e-06 27.6 0.5 3.7e-06 27.0 0.3 1.5 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KFX87478.1 - 2.3e-05 24.6 0.1 5.6e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KFX87478.1 - 9.6e-05 21.2 0.1 0.026 13.2 0.1 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KFX87478.1 - 9.8e-05 21.3 0.1 0.0024 16.8 0.0 2.3 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.20 KFX87478.1 - 0.0069 16.3 0.1 0.019 14.8 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KFX87478.1 - 0.01 14.7 0.1 0.035 13.0 0.1 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein TrkA_N PF02254.13 KFX87478.1 - 0.016 15.2 0.3 0.048 13.6 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain SPX PF03105.14 KFX87479.1 - 0.79 9.4 6.1 2 8.1 4.2 1.9 1 1 0 1 1 1 0 SPX domain GCV_T PF01571.16 KFX87480.1 - 2.9e-13 49.6 0.0 2.2e-12 46.7 0.0 2.2 3 0 0 3 3 3 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KFX87480.1 - 0.0012 18.8 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Bax1-I PF01027.15 KFX87496.1 - 6.5e-32 110.8 13.8 6.5e-32 110.8 9.6 1.5 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 APC_CDC26 PF10471.4 KFX87498.1 - 1.9 9.2 10.2 0.21 12.3 3.5 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DnaJ PF00226.26 KFX87501.1 - 4e-22 77.7 2.9 8.4e-22 76.6 0.1 2.6 2 0 0 2 2 2 1 DnaJ domain RestrictionSfiI PF11487.3 KFX87501.1 - 0.0093 15.1 0.9 0.014 14.5 0.6 1.3 1 0 0 1 1 1 1 Type II restriction enzyme SfiI RPT PF13446.1 KFX87501.1 - 0.015 14.7 1.1 0.66 9.4 0.0 2.6 2 0 0 2 2 2 0 A repeated domain in UCH-protein UPF0223 PF05256.7 KFX87501.1 - 0.46 10.6 4.7 1.1 9.4 2.6 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0223) zf-C2H2 PF00096.21 KFX87503.1 - 7.1e-08 32.3 7.1 0.0015 18.7 0.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX87503.1 - 2.6e-06 27.3 9.0 0.0017 18.5 1.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger MbtH PF03621.8 KFX87503.1 - 0.069 12.5 0.5 0.15 11.4 0.3 1.5 1 0 0 1 1 1 0 MbtH-like protein zf-H2C2_2 PF13465.1 KFX87503.1 - 3.1 8.2 7.5 7.8 6.9 1.2 3.1 3 0 0 3 3 3 0 Zinc-finger double domain Iso_dh PF00180.15 KFX87512.1 - 1.5e-101 339.8 0.0 1.8e-101 339.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.2 KFX87512.1 - 0.032 14.1 0.0 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif E1-E2_ATPase PF00122.15 KFX87517.1 - 1.4e-64 217.3 0.6 9.9e-64 214.5 0.2 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KFX87517.1 - 3.8e-23 83.0 0.2 1.1e-22 81.5 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFX87517.1 - 2.8e-13 50.4 0.0 6.9e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFX87517.1 - 4.6e-10 38.8 0.0 1.2e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KFX87517.1 - 0.0014 18.2 0.1 0.0035 16.9 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFX87517.1 - 0.0037 17.1 0.0 0.0078 16.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit FA_desaturase PF00487.19 KFX87518.1 - 0.00021 20.8 1.2 0.00027 20.4 0.8 1.1 1 0 0 1 1 1 1 Fatty acid desaturase SUN PF03856.8 KFX87519.1 - 2e-85 286.0 12.9 2.5e-85 285.7 8.9 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) CAP_GLY PF01302.20 KFX87525.1 - 4.2e-16 58.3 0.3 9.5e-16 57.2 0.2 1.6 1 0 0 1 1 1 1 CAP-Gly domain Med4 PF10018.4 KFX87525.1 - 0.003 16.9 2.0 0.003 16.9 1.4 3.7 4 0 0 4 4 4 2 Vitamin-D-receptor interacting Mediator subunit 4 DUF3552 PF12072.3 KFX87525.1 - 0.01 15.0 2.8 0.01 15.0 1.9 3.2 2 1 0 3 3 2 0 Domain of unknown function (DUF3552) NPV_P10 PF05531.7 KFX87525.1 - 0.021 15.0 4.0 4.8 7.5 0.3 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Bacillus_HBL PF05791.6 KFX87525.1 - 0.03 13.7 5.8 4.4 6.6 0.1 3.1 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) tRNA-synt_1d PF00750.14 KFX87525.1 - 0.058 12.2 1.8 0.096 11.4 1.3 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (R) LOH1CR12 PF10158.4 KFX87525.1 - 0.28 10.9 2.0 6.6 6.5 0.2 2.4 2 0 0 2 2 2 0 Tumour suppressor protein TPR_MLP1_2 PF07926.7 KFX87525.1 - 0.41 10.4 31.5 0.064 12.9 6.1 3.5 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.4 KFX87525.1 - 0.47 10.6 15.4 12 6.1 2.0 3.9 4 1 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Phage_GP20 PF06810.6 KFX87525.1 - 1.2 8.5 26.5 0.52 9.7 3.0 4.4 3 1 0 4 4 4 0 Phage minor structural protein GP20 Pkip-1 PF06878.6 KFX87525.1 - 1.9 8.3 8.4 2.3 8.0 0.8 2.3 1 1 1 2 2 2 0 Pkip-1 protein Spc7 PF08317.6 KFX87525.1 - 1.9 7.0 33.0 0.03 12.9 5.0 3.2 1 1 2 3 3 3 0 Spc7 kinetochore protein AAA_13 PF13166.1 KFX87525.1 - 2.4 6.5 25.0 0.033 12.6 5.3 2.5 1 1 2 3 3 3 0 AAA domain Tup_N PF08581.5 KFX87525.1 - 4.6 7.5 22.9 1.9 8.7 0.9 4.4 4 1 1 5 5 5 0 Tup N-terminal Laminin_II PF06009.7 KFX87525.1 - 6.8 6.4 17.2 1.8 8.2 0.8 3.3 2 1 2 4 4 4 0 Laminin Domain II TMF_DNA_bd PF12329.3 KFX87525.1 - 7 6.5 44.0 1.5 8.7 2.0 5.4 4 2 1 5 5 5 0 TATA element modulatory factor 1 DNA binding zf-TRAF PF02176.13 KFX87529.1 - 2.6e-10 40.5 17.5 4e-05 23.9 1.2 3.9 1 1 2 3 3 3 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 KFX87529.1 - 2.2e-07 30.7 5.8 2.2e-07 30.7 4.0 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX87529.1 - 2.6e-07 30.2 4.1 2.6e-07 30.2 2.9 2.8 2 1 1 3 3 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFX87529.1 - 2.8e-07 30.2 5.4 2.8e-07 30.2 3.7 2.7 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFX87529.1 - 1.8e-06 27.5 5.2 1.8e-06 27.5 3.6 2.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFX87529.1 - 1.9e-05 24.2 3.7 1.9e-05 24.2 2.6 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFX87529.1 - 5.3e-05 23.0 6.9 5.3e-05 23.0 4.8 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFX87529.1 - 0.00025 20.6 3.6 0.00025 20.6 2.5 2.3 2 0 0 2 2 2 1 RING-type zinc-finger Sina PF03145.11 KFX87529.1 - 0.011 15.3 5.6 1.8 8.2 0.0 2.5 2 1 0 2 2 2 0 Seven in absentia protein family zf-RING_6 PF14835.1 KFX87529.1 - 0.018 14.7 2.2 0.018 14.7 1.5 2.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-Nse PF11789.3 KFX87529.1 - 0.16 11.4 11.6 1.2 8.7 8.0 2.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C4H2 PF10146.4 KFX87529.1 - 4.8 7.1 9.8 20 5.0 0.0 2.7 2 1 0 2 2 2 0 Zinc finger-containing protein Mpv17_PMP22 PF04117.7 KFX87535.1 - 2e-10 40.1 1.9 9.5e-10 37.9 0.7 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family UPF0154 PF03672.8 KFX87535.1 - 0.043 13.4 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Glyco_hydro_88 PF07470.8 KFX87550.1 - 1.9e-10 40.2 0.0 3.7e-10 39.3 0.0 1.5 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 Sugar_tr PF00083.19 KFX87551.1 - 1.4e-85 287.5 20.7 1.7e-85 287.3 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX87551.1 - 4.4e-31 107.8 21.9 6.1e-31 107.4 11.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.10 KFX87551.1 - 0.0013 17.5 5.1 0.0013 17.5 3.5 2.2 2 0 0 2 2 2 1 PUCC protein V-SNARE PF05008.10 KFX87563.1 - 2.2e-22 79.0 4.3 2.9e-22 78.6 2.9 1.2 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus DUF4175 PF13779.1 KFX87563.1 - 0.0026 15.5 0.8 0.0028 15.4 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4175) RRF PF01765.14 KFX87563.1 - 0.12 11.8 1.1 0.16 11.3 0.8 1.3 1 0 0 1 1 1 0 Ribosome recycling factor Histone_HNS PF00816.16 KFX87563.1 - 0.22 12.0 1.1 0.33 11.4 0.8 1.3 1 0 0 1 1 1 0 H-NS histone family XhlA PF10779.4 KFX87563.1 - 0.31 10.9 2.4 11 6.0 0.0 2.2 2 0 0 2 2 2 0 Haemolysin XhlA Seryl_tRNA_N PF02403.17 KFX87563.1 - 0.37 10.8 4.2 4.1 7.4 0.0 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ATP-synt_B PF00430.13 KFX87563.1 - 1.7 8.4 6.1 1 9.1 2.6 1.8 2 1 0 2 2 2 0 ATP synthase B/B' CF(0) Complex1_LYR_1 PF13232.1 KFX87563.1 - 1.8 8.8 6.7 4 7.7 1.1 2.8 1 1 2 3 3 3 0 Complex1_LYR-like Transp_cyt_pur PF02133.10 KFX87564.1 - 6.9e-48 163.2 35.2 8e-48 163.0 24.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4149 PF13664.1 KFX87564.1 - 2.2 8.3 24.1 0.56 10.2 0.6 4.4 2 2 2 4 4 4 0 Domain of unknown function (DUF4149) Pectate_lyase PF03211.8 KFX87565.1 - 7.8e-79 264.0 5.3 1e-78 263.6 3.7 1.0 1 0 0 1 1 1 1 Pectate lyase GFO_IDH_MocA PF01408.17 KFX87572.1 - 3.9e-23 82.2 0.1 1.1e-22 80.8 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KFX87572.1 - 3.4e-05 23.6 0.0 9.2e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 KFX87572.1 - 0.00029 21.1 0.0 0.00059 20.2 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain AAA_33 PF13671.1 KFX87572.1 - 0.12 12.2 0.0 0.35 10.7 0.0 1.7 1 1 1 2 2 2 0 AAA domain Crystall PF00030.14 KFX87573.1 - 0.00016 21.4 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall_3 PF08964.5 KFX87573.1 - 0.086 12.5 0.7 4.7 7.0 0.0 2.7 2 2 0 2 2 2 0 Beta/Gamma crystallin Filament PF00038.16 KFX87574.1 - 0.0032 16.9 23.6 0.0032 16.9 16.4 4.5 3 2 2 5 5 5 2 Intermediate filament protein DUF641 PF04859.7 KFX87574.1 - 0.0057 16.4 1.2 0.0057 16.4 0.8 6.0 3 2 3 6 6 6 1 Plant protein of unknown function (DUF641) Spc7 PF08317.6 KFX87574.1 - 0.055 12.1 40.3 0.37 9.4 3.1 4.9 3 1 2 5 5 5 0 Spc7 kinetochore protein FlaC_arch PF05377.6 KFX87574.1 - 0.39 10.6 14.7 3.7 7.5 0.2 5.7 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.5 KFX87574.1 - 1.4 9.0 26.3 0.1 12.7 1.5 5.3 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family Exo_endo_phos PF03372.18 KFX87577.1 - 7.4e-15 55.5 0.1 1.4e-14 54.6 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Lantibiotic_a PF14867.1 KFX87577.1 - 0.022 13.9 0.6 0.045 13.0 0.2 1.7 2 0 0 2 2 2 0 Lantibiotic alpha MmoB_DmpM PF02406.12 KFX87578.1 - 0.017 15.0 0.0 0.042 13.8 0.0 1.7 1 0 0 1 1 1 0 MmoB/DmpM family adh_short_C2 PF13561.1 KFX87579.1 - 8.8e-24 84.5 1.2 1.2e-23 84.2 0.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFX87579.1 - 1.6e-19 70.4 2.7 2.8e-19 69.6 1.9 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX87579.1 - 3.9e-07 29.9 3.0 5.3e-06 26.2 2.1 2.0 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 KFX87579.1 - 0.0014 17.5 2.8 0.11 11.3 0.7 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain 2-Hacid_dh_C PF02826.14 KFX87579.1 - 0.0049 16.0 0.6 0.0097 15.0 0.1 1.8 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KFX87579.1 - 0.006 16.3 0.8 0.016 14.9 0.3 1.9 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Epimerase PF01370.16 KFX87579.1 - 0.0061 16.0 0.3 0.095 12.1 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF3698 PF12479.3 KFX87579.1 - 0.0087 16.1 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3698) ApbA PF02558.11 KFX87579.1 - 0.024 14.0 0.1 0.046 13.1 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KFX87579.1 - 0.024 14.2 0.6 0.039 13.5 0.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KFX87579.1 - 0.038 12.9 0.4 0.058 12.3 0.3 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF3150 PF11348.3 KFX87579.1 - 0.041 12.9 0.1 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) HisG PF01634.13 KFX87581.1 - 1.6e-48 164.4 0.6 3e-47 160.2 0.2 2.4 2 1 0 2 2 2 1 ATP phosphoribosyltransferase HisG_C PF08029.6 KFX87581.1 - 1.6e-27 95.2 0.2 3e-27 94.3 0.1 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 KFX87581.1 - 0.093 12.3 0.0 4 6.9 0.0 2.7 2 2 0 2 2 2 0 NMT1/THI5 like HET PF06985.6 KFX87586.1 - 6.3e-28 97.6 0.4 1.1e-27 96.9 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PAPS_reduct PF01507.14 KFX87588.1 - 1.6e-08 34.5 0.0 2.4e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Pectate_lyase_3 PF12708.2 KFX87589.1 - 1.4e-79 267.4 22.3 8.4e-61 205.9 6.6 3.7 2 1 1 3 3 3 2 Pectate lyase superfamily protein PAN_3 PF08277.7 KFX87589.1 - 3.9e-07 29.5 31.6 0.025 14.1 0.6 5.1 5 0 0 5 5 5 4 PAN-like domain End_N_terminal PF12218.3 KFX87589.1 - 2.3e-05 23.7 7.6 0.029 13.8 0.1 3.3 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase PAN_4 PF14295.1 KFX87589.1 - 1.4 8.6 37.5 0.64 9.7 1.5 5.4 5 0 0 5 5 5 0 PAN domain Pro_isomerase PF00160.16 KFX87600.1 - 1.9e-49 167.8 0.0 2.1e-49 167.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_A22B PF04258.8 KFX87601.1 - 9e-53 179.6 0.1 3.2e-52 177.8 0.1 1.7 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 KFX87601.1 - 0.0018 17.4 13.9 0.055 12.5 6.6 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1119) Presenilin PF01080.12 KFX87601.1 - 0.16 10.8 1.7 0.78 8.5 0.2 2.5 3 0 0 3 3 3 0 Presenilin AMP-binding_C PF13193.1 KFX87603.1 - 3.6e-16 59.8 0.1 5.6e-15 56.0 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HATPase_c PF02518.21 KFX87603.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TraV PF09676.5 KFX87607.1 - 2.7 8.7 5.8 0.31 11.7 1.0 1.6 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Polyketide_cyc PF03364.15 KFX87608.1 - 1e-23 83.7 0.0 2.3e-23 82.6 0.0 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 KFX87608.1 - 0.006 16.7 0.0 1.2 9.3 0.0 2.1 2 0 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport Methyltransf_12 PF08242.7 KFX87609.1 - 2.8e-15 56.6 0.0 7.3e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX87609.1 - 4.4e-12 46.3 0.0 8.7e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX87609.1 - 1.3e-11 44.7 0.0 2.6e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX87609.1 - 1.4e-11 44.3 0.0 2.3e-11 43.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX87609.1 - 4.1e-09 36.2 0.0 7.2e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX87609.1 - 2.9e-08 33.1 0.0 4.5e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KFX87609.1 - 1.1e-07 32.3 0.0 2.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX87609.1 - 6e-05 23.0 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX87609.1 - 0.00057 19.2 0.0 0.00099 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 KFX87609.1 - 0.0014 18.0 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase DUF3419 PF11899.3 KFX87609.1 - 0.0037 16.0 0.0 0.0055 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) PrmA PF06325.8 KFX87609.1 - 0.0071 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NNMT_PNMT_TEMT PF01234.12 KFX87609.1 - 0.013 14.5 0.0 0.41 9.5 0.0 2.2 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_8 PF05148.10 KFX87609.1 - 0.013 15.1 0.0 0.045 13.3 0.0 1.8 1 1 1 2 2 2 0 Hypothetical methyltransferase Methyltransf_24 PF13578.1 KFX87609.1 - 0.046 14.5 0.0 0.1 13.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 KFX87609.1 - 0.096 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Nucleoplasmin PF03066.10 KFX87610.1 - 0.012 15.1 9.4 0.012 15.1 6.5 2.1 2 0 0 2 2 2 0 Nucleoplasmin Nop14 PF04147.7 KFX87610.1 - 0.021 12.7 4.3 0.024 12.6 3.0 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KFX87610.1 - 0.066 11.7 3.2 0.089 11.2 2.2 1.1 1 0 0 1 1 1 0 Daxx Family TFIIA PF03153.8 KFX87610.1 - 1.1 9.1 15.2 1.3 8.8 10.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TRAPP PF04051.11 KFX87614.1 - 2.7e-34 117.8 0.0 3.2e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ldh_1_N PF00056.18 KFX87615.1 - 4.3e-44 149.7 0.2 6.1e-44 149.2 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KFX87615.1 - 2.1e-42 144.7 0.0 3e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KFX87615.1 - 0.00081 18.1 0.0 0.0012 17.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 KFX87615.1 - 0.037 13.1 0.2 0.24 10.4 0.1 2.3 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_4 PF02056.11 KFX87615.1 - 0.089 12.1 0.3 2.2 7.5 0.2 2.2 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase Peptidase_M36 PF02128.10 KFX87633.1 - 9.5e-160 531.5 5.6 1.2e-159 531.1 3.9 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 KFX87633.1 - 3.3e-11 42.4 2.1 9.9e-11 40.9 1.5 1.9 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 KFX87633.1 - 0.0046 16.7 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_MA_2 PF13485.1 KFX87633.1 - 0.067 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily ComA PF02679.10 KFX87636.1 - 4.5e-79 264.9 0.0 5.3e-79 264.6 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) DUF2542 PF10808.3 KFX87636.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2542) AAA PF00004.24 KFX87645.1 - 9.8e-43 145.5 0.1 2.4e-42 144.2 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFX87645.1 - 3.9e-08 32.6 0.0 6.3e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KFX87645.1 - 3.2e-05 24.0 0.0 0.00019 21.4 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 KFX87645.1 - 3.6e-05 23.5 0.1 0.00035 20.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KFX87645.1 - 5.7e-05 23.0 0.0 0.00072 19.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 KFX87645.1 - 6.8e-05 22.8 0.0 0.00021 21.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 KFX87645.1 - 8.3e-05 22.0 0.6 0.29 10.5 0.0 3.1 1 1 2 3 3 3 2 AAA domain AAA_17 PF13207.1 KFX87645.1 - 0.00014 22.6 0.0 0.00043 21.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFX87645.1 - 0.00019 21.1 0.0 0.0017 18.0 0.0 2.5 3 0 0 3 3 2 1 Part of AAA domain KaiC PF06745.8 KFX87645.1 - 0.00038 19.6 0.1 0.014 14.4 0.0 2.5 2 0 0 2 2 2 1 KaiC AAA_22 PF13401.1 KFX87645.1 - 0.00056 20.0 0.2 0.013 15.6 0.0 2.9 3 1 0 3 3 2 1 AAA domain IstB_IS21 PF01695.12 KFX87645.1 - 0.00093 18.6 0.0 0.0021 17.4 0.0 1.5 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 KFX87645.1 - 0.0015 18.4 0.0 0.0052 16.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 KFX87645.1 - 0.002 18.0 0.0 0.011 15.6 0.0 2.0 2 0 0 2 2 2 1 Cytidylate kinase-like family RNA_helicase PF00910.17 KFX87645.1 - 0.0022 18.1 0.0 0.0079 16.3 0.0 2.0 1 1 0 1 1 1 1 RNA helicase TIP49 PF06068.8 KFX87645.1 - 0.0022 16.7 0.2 0.0049 15.6 0.1 1.6 1 1 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 KFX87645.1 - 0.0025 18.1 0.0 0.0077 16.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KFX87645.1 - 0.0033 17.0 0.0 0.0066 16.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KFX87645.1 - 0.0034 16.5 0.2 0.021 13.8 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_28 PF13521.1 KFX87645.1 - 0.0034 17.3 0.0 0.0077 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KFX87645.1 - 0.0054 16.4 0.0 0.052 13.2 0.0 2.5 2 1 1 3 3 3 1 NACHT domain Mg_chelatase PF01078.16 KFX87645.1 - 0.0064 15.6 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.10 KFX87645.1 - 0.04 12.6 0.0 0.057 12.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Disulph_isomer PF06491.6 KFX87645.1 - 0.051 13.4 0.1 0.13 12.0 0.1 1.7 1 0 0 1 1 1 0 Disulphide isomerase Sigma54_activ_2 PF14532.1 KFX87645.1 - 0.065 13.2 0.0 0.44 10.5 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain SKI PF01202.17 KFX87645.1 - 0.095 12.5 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 Shikimate kinase Arch_ATPase PF01637.13 KFX87645.1 - 0.097 12.3 0.5 1.1 8.9 0.0 2.5 2 1 0 2 2 2 0 Archaeal ATPase ORC6 PF05460.8 KFX87645.1 - 0.14 11.2 2.4 0.28 10.2 1.7 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Snf7 PF03357.16 KFX87646.1 - 6.6e-33 113.4 10.5 8.3e-33 113.1 7.3 1.2 1 0 0 1 1 1 1 Snf7 DUF2520 PF10728.4 KFX87646.1 - 0.017 14.6 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) Heme_oxygenase PF01126.15 KFX87646.1 - 0.025 14.1 0.1 0.037 13.6 0.1 1.3 1 0 0 1 1 1 0 Heme oxygenase XAP5 PF04921.9 KFX87646.1 - 0.073 12.6 4.1 0.098 12.2 2.9 1.4 1 1 0 1 1 1 0 XAP5, circadian clock regulator DELLA PF12041.3 KFX87646.1 - 1.4 8.6 5.5 13 5.5 0.2 3.1 2 1 1 3 3 3 0 Transcriptional regulator DELLA protein N terminal DUF2203 PF09969.4 KFX87646.1 - 1.6 8.9 4.2 1 9.5 0.3 2.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) YlqD PF11068.3 KFX87646.1 - 6.8 6.7 11.3 10 6.1 1.7 2.3 1 1 0 2 2 2 0 YlqD protein Cytochrome_CBB3 PF13442.1 KFX87647.1 - 6.1e-09 35.9 0.6 4.8e-08 33.0 0.4 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 KFX87647.1 - 7.5e-09 36.3 0.0 1.1e-08 35.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrom_C550 PF14495.1 KFX87647.1 - 9.2e-05 21.9 0.2 0.0007 19.0 0.0 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain Flavokinase PF01687.12 KFX87664.1 - 1.1e-35 122.2 0.0 1.3e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase Zn_clus PF00172.13 KFX87665.1 - 0.0051 16.6 9.6 0.0051 16.6 6.7 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 KFX87665.1 - 0.013 15.2 0.0 0.037 13.8 0.0 1.7 2 0 0 2 2 2 0 PAS fold PX PF00787.19 KFX87668.1 - 1e-21 76.8 0.0 1.3e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 PX domain IQ PF00612.22 KFX87669.1 - 0.0015 17.9 3.2 0.004 16.6 2.2 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif 2-oxoacid_dh PF00198.18 KFX87672.1 - 1.6e-76 256.6 0.8 3e-76 255.7 0.2 1.6 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KFX87672.1 - 6.8e-19 67.2 0.0 1.4e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KFX87672.1 - 5.3e-13 48.3 0.1 1.7e-12 46.7 0.0 2.0 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 KFX87672.1 - 0.051 13.2 0.1 0.54 9.9 0.0 2.4 1 1 1 2 2 2 0 Biotin-lipoyl like His_Phos_1 PF00300.17 KFX87678.1 - 8.2e-33 113.7 0.2 1.9e-32 112.5 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 KFX87678.1 - 0.0067 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) zf-C2H2 PF00096.21 KFX87684.1 - 2.2e-13 49.6 19.5 7.2e-05 22.8 1.4 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFX87684.1 - 1.4e-10 40.9 19.9 4.2e-09 36.2 0.5 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFX87684.1 - 1.5e-09 37.4 14.0 0.0048 17.1 0.0 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger GAGA PF09237.6 KFX87684.1 - 0.039 13.5 0.6 5.9 6.5 0.1 2.5 1 1 1 2 2 2 0 GAGA factor Ogr_Delta PF04606.7 KFX87684.1 - 0.25 11.0 3.6 7.8 6.2 0.1 2.5 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Zn-ribbon_8 PF09723.5 KFX87684.1 - 9.3 6.2 7.8 12 5.9 1.8 2.9 2 1 0 2 2 2 0 Zinc ribbon domain CFEM PF05730.6 KFX87687.1 - 1.3e-09 37.7 10.1 2.5e-09 36.8 7.0 1.5 1 0 0 1 1 1 1 CFEM domain Histone PF00125.19 KFX87691.1 - 1.4e-31 108.4 0.4 2.2e-31 107.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFX87691.1 - 2.7e-06 27.4 0.1 4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KFX87691.1 - 0.004 17.1 0.0 0.0086 16.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KFX87691.1 - 0.045 13.4 0.1 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Zn_clus PF00172.13 KFX87693.1 - 5.6e-10 38.9 7.8 1.3e-09 37.7 5.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFX87693.1 - 2.9e-06 26.1 0.0 5.6e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tenui_NCP PF04876.7 KFX87693.1 - 0.2 11.1 0.0 0.43 10.0 0.0 1.5 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein CUE PF02845.11 KFX87702.1 - 1.6e-11 43.4 0.0 2.7e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 CUE domain BacteriocIIc_cy PF12173.3 KFX87702.1 - 0.25 11.3 2.7 0.41 10.7 1.9 1.3 1 0 0 1 1 1 0 Bacteriocin class IIc cyclic gassericin A-like DUF1109 PF06532.6 KFX87703.1 - 0.1 12.0 0.6 0.15 11.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1109) DUF1996 PF09362.5 KFX87728.1 - 3.6e-91 305.0 1.0 5.2e-91 304.4 0.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TPR_11 PF13414.1 KFX87729.1 - 2.7e-10 39.7 0.0 7.1e-08 31.9 0.0 2.6 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFX87729.1 - 4.7e-07 29.2 0.0 0.22 11.5 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFX87729.1 - 5.5e-06 26.2 0.0 0.027 14.4 0.0 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat LRR_4 PF12799.2 KFX87729.1 - 8.6e-06 25.2 11.4 0.067 12.8 0.4 5.9 7 0 0 7 7 7 3 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KFX87729.1 - 1.3e-05 24.8 0.1 2.6e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX87729.1 - 0.00015 21.3 0.0 0.00057 19.4 0.0 2.0 2 0 0 2 2 2 1 F-box domain TPR_1 PF00515.23 KFX87729.1 - 0.00075 19.0 0.0 0.77 9.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat LRR_7 PF13504.1 KFX87729.1 - 0.0056 16.6 8.4 38 5.1 0.2 6.6 7 0 0 7 7 6 0 Leucine rich repeat TPR_14 PF13428.1 KFX87729.1 - 0.0086 16.6 0.1 18 6.3 0.0 3.9 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFX87729.1 - 0.047 13.4 0.0 7.3 6.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_6 PF13516.1 KFX87729.1 - 0.059 13.4 5.0 68 4.0 0.1 5.3 5 0 0 5 5 5 0 Leucine Rich repeat LRR_8 PF13855.1 KFX87729.1 - 0.18 11.5 11.6 0.78 9.5 1.0 4.9 6 1 1 7 7 7 0 Leucine rich repeat LRR_1 PF00560.28 KFX87729.1 - 0.56 10.4 8.7 1.1e+02 3.4 0.0 5.8 6 0 0 6 6 5 0 Leucine Rich Repeat CTNNBL PF08216.6 KFX87730.1 - 4.1e-36 122.8 1.3 1.4e-35 121.1 0.1 2.3 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear SpecificRecomb PF10136.4 KFX87730.1 - 0.0041 15.2 0.1 0.007 14.4 0.0 1.3 1 0 0 1 1 1 1 Site-specific recombinase Arm PF00514.18 KFX87730.1 - 0.0043 16.8 0.0 0.36 10.7 0.0 3.4 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFX87730.1 - 0.022 15.0 3.5 1.1 9.6 0.1 3.1 1 1 0 2 2 2 0 HEAT repeats Sugar_tr PF00083.19 KFX87731.1 - 2.5e-68 230.7 19.6 2.9e-68 230.5 13.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX87731.1 - 2.7e-13 49.3 27.7 2.7e-13 49.3 19.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX87731.1 - 1.3e-06 27.0 23.4 3.1e-05 22.5 3.7 3.3 3 1 1 4 4 4 2 MFS/sugar transport protein DUF4535 PF15054.1 KFX87731.1 - 0.25 10.7 1.0 0.54 9.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) DUF2301 PF10063.4 KFX87731.1 - 0.37 11.0 6.5 1.8 8.7 0.3 2.9 3 0 0 3 3 3 0 Uncharacterized integral membrane protein (DUF2301) HNH_2 PF13391.1 KFX87736.1 - 3.4e-18 65.1 0.0 5.7e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease E1-E2_ATPase PF00122.15 KFX87737.1 - 2.6e-54 183.6 0.2 5.5e-54 182.6 0.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFX87737.1 - 2.2e-47 162.2 2.7 3.2e-47 161.7 1.2 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KFX87737.1 - 3.1e-47 158.5 0.0 4.7e-12 45.8 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 KFX87737.1 - 2.3e-14 53.9 0.0 5.2e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFX87737.1 - 4.3e-05 23.2 3.1 0.00011 21.8 0.9 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3133 PF11331.3 KFX87737.1 - 0.19 11.3 3.9 31 4.2 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) TPR_11 PF13414.1 KFX87738.1 - 1e-06 28.2 4.6 0.0083 15.7 0.0 5.5 3 2 1 5 5 5 2 TPR repeat TPR_12 PF13424.1 KFX87738.1 - 2.2e-06 27.5 8.0 0.044 13.7 0.4 5.1 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFX87738.1 - 0.0036 17.7 8.0 12 6.8 0.0 7.0 6 1 1 7 7 7 1 Tetratricopeptide repeat DUF4164 PF13747.1 KFX87738.1 - 0.057 13.5 3.4 33 4.7 0.1 4.9 3 2 2 5 5 5 0 Domain of unknown function (DUF4164) TPR_2 PF07719.12 KFX87738.1 - 0.46 10.5 9.2 57 3.9 0.0 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat Halo_GVPC PF05465.8 KFX87738.1 - 0.96 9.4 3.5 3.1 7.8 0.0 3.1 3 0 0 3 3 3 0 Halobacterial gas vesicle protein C (GVPC) repeat O-FucT PF10250.4 KFX87739.1 - 7.8e-11 41.6 0.0 0.00011 21.4 0.0 3.0 1 1 1 2 2 2 2 GDP-fucose protein O-fucosyltransferase PCI PF01399.22 KFX87740.1 - 9.1e-07 29.1 0.0 1.4e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 PCI domain Abhydrolase_5 PF12695.2 KFX87745.1 - 9.9e-07 28.6 0.0 1.4e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX87745.1 - 4.4e-05 23.4 0.0 0.00017 21.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family FHA PF00498.21 KFX87750.1 - 3.1e-12 46.4 0.1 1.2e-11 44.5 0.0 2.1 2 0 0 2 2 2 1 FHA domain IFRD PF05004.8 KFX87751.1 - 1.2e-32 113.2 3.6 1.7e-32 112.7 2.5 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.1 KFX87751.1 - 2.8e-05 24.3 3.3 0.018 15.2 0.3 2.5 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.17 KFX87751.1 - 0.098 12.7 0.1 33 4.9 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat RAP1 PF07218.6 KFX87751.1 - 0.36 8.8 4.4 0.53 8.3 3.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Corona_nucleoca PF00937.13 KFX87751.1 - 0.58 9.0 6.9 0.95 8.3 4.8 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein LIP PF03583.9 KFX87770.1 - 4.3e-23 81.9 0.1 5.9e-23 81.4 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 KFX87770.1 - 8.4e-08 32.3 0.1 1.2e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX87770.1 - 3.7e-07 30.0 0.0 5.3e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KFX87770.1 - 0.0027 17.1 0.1 0.0083 15.5 0.0 1.7 2 0 0 2 2 2 1 Putative esterase DUF1749 PF08538.5 KFX87770.1 - 0.0033 16.3 0.0 0.0053 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Peptidase_S15 PF02129.13 KFX87770.1 - 0.0067 15.8 0.0 0.0089 15.4 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.8 KFX87770.1 - 0.0092 15.5 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFX87770.1 - 0.01 15.0 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2974 PF11187.3 KFX87770.1 - 0.012 14.9 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.20 KFX87770.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.2 KFX87770.1 - 0.014 14.2 0.0 0.028 13.2 0.0 1.4 2 0 0 2 2 2 0 Chlorophyllase enzyme Abhydrolase_2 PF02230.11 KFX87770.1 - 0.019 14.3 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Chlorophyllase PF07224.6 KFX87770.1 - 0.029 13.1 0.0 0.048 12.4 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase DUF3089 PF11288.3 KFX87770.1 - 0.062 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF1057 PF06342.7 KFX87770.1 - 0.18 10.6 0.0 0.32 9.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Aldo_ket_red PF00248.16 KFX87774.1 - 9e-17 60.8 0.0 9.8e-17 60.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TFIIA PF03153.8 KFX87775.1 - 8.2 6.2 7.4 17 5.1 5.1 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rotamase_3 PF13616.1 KFX87778.1 - 8.2e-15 55.0 0.1 1.1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 KFX87778.1 - 1.4e-14 54.5 0.0 2e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KFX87778.1 - 0.0014 19.2 0.1 0.0023 18.5 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Methyltransf_2 PF00891.13 KFX87779.1 - 6.2e-30 104.1 0.0 1.7e-29 102.7 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase FeoC PF09012.5 KFX87779.1 - 0.0052 16.4 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 FeoC like transcriptional regulator MarR_2 PF12802.2 KFX87779.1 - 0.022 14.3 0.0 0.05 13.2 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_27 PF13463.1 KFX87779.1 - 0.075 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain HTH_24 PF13412.1 KFX87779.1 - 0.11 11.8 0.0 0.26 10.6 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding SOR_SNZ PF01680.12 KFX87781.1 - 6.5e-113 375.4 7.0 6.5e-113 375.4 4.9 1.6 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.9 KFX87781.1 - 4.8e-08 32.3 7.4 8.5e-07 28.2 0.3 2.6 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KFX87781.1 - 0.0049 16.1 0.7 0.093 11.9 0.0 2.6 2 1 1 3 3 3 1 Histidine biosynthesis protein IGPS PF00218.16 KFX87781.1 - 0.014 14.4 0.1 0.081 11.9 0.0 2.2 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase NanE PF04131.9 KFX87781.1 - 0.018 13.9 0.9 0.13 11.2 0.0 2.4 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Dus PF01207.12 KFX87781.1 - 0.022 13.6 0.9 0.72 8.6 0.1 2.5 2 1 0 2 2 2 0 Dihydrouridine synthase (Dus) NMO PF03060.10 KFX87781.1 - 0.032 13.3 3.7 0.034 13.3 0.2 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase LysM PF01476.15 KFX87782.1 - 1.1e-10 41.2 0.0 0.00013 21.7 0.0 3.5 3 0 0 3 3 3 2 LysM domain PAN_4 PF14295.1 KFX87782.1 - 5.7e-05 22.7 20.7 0.062 13.0 0.3 5.2 5 0 0 5 5 5 3 PAN domain PAN_3 PF08277.7 KFX87782.1 - 0.00058 19.4 16.2 0.081 12.5 0.1 5.1 5 0 0 5 5 5 3 PAN-like domain Toxin_28 PF08115.6 KFX87782.1 - 0.35 10.5 3.8 0.42 10.3 0.4 2.5 2 0 0 2 2 2 0 SFI toxin family PAN_2 PF08276.6 KFX87782.1 - 2.1 8.2 17.8 2 8.2 0.2 3.9 4 0 0 4 4 4 0 PAN-like domain FAD_binding_4 PF01565.18 KFX87785.1 - 7.2e-23 80.5 0.3 1.2e-22 79.8 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFX87785.1 - 0.0028 17.5 0.1 0.006 16.4 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like CDC27 PF09507.5 KFX87786.1 - 0.023 13.9 3.4 0.044 12.9 2.4 1.6 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF3525 PF12039.3 KFX87786.1 - 0.7 8.3 3.5 0.65 8.4 0.2 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3525) Dicty_REP PF05086.7 KFX87786.1 - 1.8 6.2 5.0 2.1 5.9 3.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Spermine_synth PF01564.12 KFX87787.1 - 1.2e-100 335.4 0.0 1.6e-100 335.0 0.0 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 KFX87787.1 - 7.5e-05 23.2 0.0 0.00017 22.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX87787.1 - 0.0005 19.6 0.0 0.0008 19.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 KFX87787.1 - 0.0019 17.2 0.0 0.0029 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_12 PF08242.7 KFX87787.1 - 0.0084 16.5 0.5 0.1 13.0 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_2 PF00891.13 KFX87787.1 - 0.034 13.3 0.1 0.13 11.4 0.0 1.8 1 1 1 2 2 2 0 O-methyltransferase Methyltransf_30 PF05430.6 KFX87787.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Mucin PF01456.12 KFX87789.1 - 9.3 6.0 12.5 12 5.7 8.6 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Asn_synthase PF00733.16 KFX87790.1 - 6.4e-52 176.5 0.0 9.9e-52 175.9 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KFX87790.1 - 4e-08 33.0 0.0 1.1e-07 31.6 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KFX87790.1 - 0.00042 20.2 0.0 0.00083 19.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Sugar_tr PF00083.19 KFX87791.1 - 5e-95 318.7 26.9 5.8e-95 318.4 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX87791.1 - 1.5e-38 132.4 44.9 1.3e-34 119.5 14.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX87791.1 - 5.6e-06 25.0 14.9 0.00026 19.5 2.2 3.6 2 2 0 3 3 3 2 MFS/sugar transport protein DNA_pol_B_palm PF14792.1 KFX87792.1 - 2e-31 108.3 0.0 3.4e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 KFX87792.1 - 4.3e-22 77.5 0.0 1.6e-21 75.7 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 KFX87792.1 - 3.8e-18 64.7 0.8 7.6e-18 63.8 0.6 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 KFX87792.1 - 1.3e-15 57.3 0.8 2.8e-15 56.2 0.2 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.2 KFX87792.1 - 0.052 13.4 0.1 12 5.9 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif BRCT PF00533.21 KFX87792.1 - 0.064 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KFX87792.1 - 0.098 12.5 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 twin BRCT domain Acetyltransf_7 PF13508.1 KFX87793.1 - 3.9e-08 33.3 0.0 5.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX87793.1 - 2e-07 31.1 0.0 2.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX87793.1 - 6.2e-06 26.1 0.0 8.4e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KFX87793.1 - 0.00012 21.9 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFX87793.1 - 0.0058 16.4 0.1 0.011 15.5 0.0 1.5 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 KFX87793.1 - 0.021 14.5 0.0 0.053 13.2 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.1 KFX87793.1 - 0.067 13.0 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SH2_2 PF14633.1 KFX87800.1 - 6.3e-53 179.0 3.6 1.7e-52 177.6 2.5 1.8 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 KFX87800.1 - 1.2e-36 125.2 6.2 1.2e-36 125.2 4.3 3.5 3 0 0 3 3 3 1 Death-like domain of SPT6 HHH_7 PF14635.1 KFX87800.1 - 2.2e-29 101.6 0.0 8.9e-29 99.6 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif YqgF PF14639.1 KFX87800.1 - 1.2e-27 96.2 0.0 5e-27 94.3 0.0 2.2 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 KFX87800.1 - 3.9e-22 78.2 20.4 3.9e-22 78.2 14.2 5.8 6 1 0 7 7 7 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 KFX87800.1 - 4.4e-19 68.6 0.9 1.2e-17 64.0 0.6 3.0 1 1 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 KFX87800.1 - 0.00018 21.2 0.0 0.00054 19.7 0.0 1.9 1 0 0 1 1 1 1 SH2 domain Pkinase PF00069.20 KFX87801.1 - 2.8e-14 52.9 0.4 3.2e-14 52.6 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX87801.1 - 6.4e-09 35.2 0.4 7.5e-09 35.0 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase BING4CT PF08149.6 KFX87818.1 - 9.7e-41 137.1 0.0 3.5e-37 125.7 0.0 3.5 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.27 KFX87818.1 - 2.4e-07 30.3 0.0 3.1e-05 23.6 0.0 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF4427 PF14468.1 KFX87818.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) SNAP PF14938.1 KFX87819.1 - 2.4e-112 374.7 13.4 2.7e-112 374.5 9.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KFX87819.1 - 3.7e-09 36.3 10.0 0.00013 21.8 2.8 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFX87819.1 - 2.8e-06 26.6 6.8 0.025 14.3 0.3 5.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFX87819.1 - 1.2e-05 24.8 11.6 0.028 14.0 0.3 3.4 1 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 KFX87819.1 - 0.0028 17.1 8.1 2.7 7.7 0.0 5.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFX87819.1 - 0.0039 16.8 9.1 0.1 12.4 0.4 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFX87819.1 - 0.0044 16.8 9.5 2.3 8.3 0.1 5.4 2 1 4 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFX87819.1 - 0.0062 17.1 9.6 0.88 10.3 0.3 3.9 1 1 3 4 4 4 2 Tetratricopeptide repeat DUF2521 PF10730.4 KFX87819.1 - 0.034 13.9 1.5 0.075 12.8 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2521) TPR_6 PF13174.1 KFX87819.1 - 0.18 12.3 12.6 8.9 7.0 0.1 5.5 3 1 2 6 6 6 0 Tetratricopeptide repeat DUF4375 PF14300.1 KFX87819.1 - 0.26 11.2 4.1 3.6 7.6 0.1 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4375) DUF2225 PF09986.4 KFX87819.1 - 1.7 8.0 5.6 5.3 6.4 3.7 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) Glu-tRNAGln PF02686.10 KFX87820.1 - 1.6e-07 30.9 0.5 8.2e-07 28.7 0.3 2.0 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit DUF4226 PF10774.4 KFX87820.1 - 0.062 13.3 0.2 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) DUF726 PF05277.7 KFX87821.1 - 7.5e-122 406.5 2.7 1e-121 406.0 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 KFX87821.1 - 0.00018 21.4 0.0 0.00043 20.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KFX87821.1 - 0.00023 21.4 0.0 0.00078 19.7 0.0 1.9 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 KFX87821.1 - 0.021 14.5 0.2 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 KFX87821.1 - 0.11 12.1 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 3) PE-PPE PF08237.6 KFX87821.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Cutinase PF01083.17 KFX87821.1 - 0.22 11.2 0.0 0.38 10.4 0.0 1.3 1 0 0 1 1 1 0 Cutinase TcdA_TcdB_pore PF12920.2 KFX87821.1 - 5.5 4.7 11.8 2.3 6.0 5.4 1.9 2 0 0 2 2 2 0 TcdA/TcdB pore forming domain DUF2514 PF10721.4 KFX87822.1 - 0.0082 15.8 4.4 0.011 15.4 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) Mnd1 PF03962.10 KFX87822.1 - 0.019 14.6 0.0 0.022 14.4 0.0 1.1 1 0 0 1 1 1 0 Mnd1 family INO80_Ies4 PF08193.6 KFX87829.1 - 7.3e-51 173.2 20.4 1e-50 172.7 14.1 1.2 1 0 0 1 1 1 1 INO80 complex subunit Ies4 Utp12 PF04003.7 KFX87831.1 - 1.2e-21 76.6 0.0 1.6e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family BUD22 PF09073.5 KFX87831.1 - 0.066 12.2 21.9 0.084 11.9 15.2 1.1 1 0 0 1 1 1 0 BUD22 Speriolin_N PF15058.1 KFX87831.1 - 7.9 6.3 8.2 16 5.3 1.8 2.2 2 0 0 2 2 2 0 Speriolin N terminus HLH PF00010.21 KFX87832.1 - 2.3e-08 33.6 0.0 5.2e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Adaptin_N PF01602.15 KFX87834.1 - 1.9e-121 405.9 5.7 2.3e-121 405.6 4.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 KFX87834.1 - 3.9e-45 152.4 0.0 8.8e-45 151.2 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 KFX87834.1 - 2.6e-21 76.0 0.0 5.2e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain MARVEL PF01284.18 KFX87836.1 - 6.9e-27 94.0 14.4 8.7e-27 93.7 10.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain MpPF26 PF07666.6 KFX87836.1 - 0.018 14.9 3.8 0.19 11.6 1.9 2.6 2 1 1 3 3 3 0 M penetrans paralogue family 26 FtsX PF02687.16 KFX87836.1 - 0.029 14.1 7.9 0.53 10.0 0.0 2.8 2 1 0 2 2 2 0 FtsX-like permease family DUF805 PF05656.9 KFX87836.1 - 1.9 8.3 0.0 1.9 8.3 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF805) CSTF_C PF14304.1 KFX87837.1 - 0.0057 15.9 1.4 0.02 14.1 0.9 1.9 1 1 0 1 1 1 1 Transcription termination and cleavage factor C-terminal Fis1_TPR_C PF14853.1 KFX87837.1 - 0.075 12.9 0.3 0.094 12.6 0.2 1.2 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TMF_TATA_bd PF12325.3 KFX87837.1 - 0.077 12.7 0.4 0.083 12.6 0.3 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding PAP1 PF08601.5 KFX87838.1 - 2e-49 169.1 36.1 2e-49 169.1 25.0 4.4 2 2 1 3 3 3 1 Transcription factor PAP1 bZIP_1 PF00170.16 KFX87838.1 - 6.5e-08 32.4 9.2 1.3e-07 31.4 6.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFX87838.1 - 0.0027 17.4 10.5 0.0071 16.1 7.2 1.7 1 1 0 1 1 1 1 Basic region leucine zipper Adeno_PIX PF03955.9 KFX87838.1 - 0.069 13.6 1.2 0.27 11.7 0.8 2.0 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) bZIP_Maf PF03131.12 KFX87838.1 - 0.37 11.1 7.7 0.81 10.0 5.4 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Herpes_UL6 PF01763.11 KFX87838.1 - 0.62 8.1 2.5 0.92 7.5 1.7 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Macoilin PF09726.4 KFX87838.1 - 4 5.5 22.6 1.9 6.7 5.9 2.2 2 0 0 2 2 2 0 Transmembrane protein Pkinase PF00069.20 KFX87852.1 - 8.7e-26 90.6 0.0 3.2e-15 55.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFX87852.1 - 2e-08 33.6 0.0 9.6e-08 31.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFX87852.1 - 7.1e-05 22.6 0.1 0.00016 21.5 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Ank_2 PF12796.2 KFX87853.1 - 7.1e-20 71.1 0.1 6.4e-05 23.2 0.0 5.8 2 1 5 7 7 7 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFX87853.1 - 8.3e-16 57.6 4.3 0.00019 21.5 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.25 KFX87853.1 - 2.4e-13 49.1 4.3 0.04 13.7 0.0 8.7 8 1 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.1 KFX87853.1 - 1.2e-11 44.8 7.5 0.11 12.9 0.0 7.0 3 2 4 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX87853.1 - 0.002 18.2 8.7 12 6.5 0.0 8.6 10 1 0 10 10 10 1 Ankyrin repeat AA_permease PF00324.16 KFX87854.1 - 1.3e-135 452.4 39.8 1.7e-135 452.0 27.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFX87854.1 - 2e-34 118.8 41.1 2.8e-34 118.3 28.5 1.2 1 0 0 1 1 1 1 Amino acid permease PDH PF02153.12 KFX87856.1 - 4.7e-13 48.6 0.0 7.2e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 KFX87856.1 - 5e-07 29.7 0.0 2.3e-06 27.5 0.0 2.1 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KFX87856.1 - 1.6e-05 25.2 0.0 3.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KFX87856.1 - 0.00015 21.5 0.0 0.00078 19.1 0.0 1.9 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KFX87856.1 - 0.0011 18.4 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 KFX87856.1 - 0.0011 18.1 0.0 0.0021 17.2 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.1 KFX87856.1 - 0.0059 16.9 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 XdhC Rossmann domain Shikimate_DH PF01488.15 KFX87856.1 - 0.042 13.9 0.0 0.37 10.9 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KFX87856.1 - 0.062 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Ribosomal_S11 PF00411.14 KFX87857.1 - 2.5e-40 137.0 0.5 3e-40 136.8 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 AAR2 PF05282.6 KFX87858.1 - 7.6e-59 199.4 0.0 1e-58 199.0 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein HisKA_3 PF07730.8 KFX87859.1 - 0.011 16.0 0.7 1.5 9.2 0.2 2.2 1 1 1 2 2 2 0 Histidine kinase AATF-Che1 PF13339.1 KFX87859.1 - 0.062 13.4 0.7 0.088 12.9 0.5 1.2 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor TMP_2 PF06791.8 KFX87859.1 - 0.062 12.9 0.1 0.14 11.7 0.0 1.5 1 1 0 1 1 1 0 Prophage tail length tape measure protein GAT PF03127.9 KFX87859.1 - 0.072 13.0 0.3 0.095 12.6 0.2 1.3 1 0 0 1 1 1 0 GAT domain DUF2564 PF10819.3 KFX87859.1 - 0.25 11.4 2.0 0.43 10.7 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2564) Sec2p PF06428.6 KFX87859.1 - 0.43 10.4 3.4 1.1 9.1 2.3 1.7 1 1 0 1 1 1 0 GDP/GTP exchange factor Sec2p IncA PF04156.9 KFX87859.1 - 0.43 10.1 4.6 0.53 9.8 3.2 1.1 1 0 0 1 1 1 0 IncA protein Ribosomal_S9 PF00380.14 KFX87860.1 - 1.5e-39 135.0 0.2 1.7e-39 134.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 WSC PF01822.14 KFX87861.1 - 4.3e-70 231.6 67.0 1.5e-19 69.6 7.2 4.4 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.6 KFX87861.1 - 1.3e-31 109.4 0.0 3.8e-30 104.7 0.0 2.7 2 1 1 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KFX87861.1 - 3e-24 84.9 0.7 3.4e-23 81.5 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 KFX87861.1 - 0.0013 18.4 1.9 2.2 8.1 0.1 4.0 3 0 0 3 3 3 1 Galactose oxidase, central domain DUF3402 PF11882.3 KFX87866.1 - 2e-145 484.9 0.0 3.5e-145 484.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 KFX87866.1 - 5.2e-71 238.8 0.0 7.1e-71 238.4 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein QCR10 PF09796.4 KFX87869.1 - 4.7e-29 99.8 0.6 6.1e-29 99.4 0.4 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Glyco_transf_90 PF05686.7 KFX87873.1 - 7.6e-19 67.6 0.0 6e-15 54.8 0.0 2.0 2 0 0 2 2 2 2 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 KFX87873.1 - 0.0058 16.8 0.0 0.012 15.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Peptidase_M22 PF00814.20 KFX87875.1 - 1.3e-14 54.3 0.0 1.5e-14 54.1 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Porin_3 PF01459.17 KFX87878.1 - 1.2e-86 290.3 0.3 1.4e-86 290.1 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin 6PF2K PF01591.13 KFX87879.1 - 5.2e-57 192.4 0.0 7.2e-57 192.0 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KFX87879.1 - 1.6e-24 86.8 0.2 2.5e-24 86.1 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 KFX87879.1 - 9.3e-07 29.7 0.1 0.0002 22.1 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 KFX87879.1 - 0.011 15.5 0.0 0.025 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KFX87879.1 - 0.027 13.8 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 KFX87879.1 - 0.064 13.0 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain APS_kinase PF01583.15 KFX87879.1 - 0.085 12.5 0.0 0.69 9.5 0.0 2.1 1 1 0 1 1 1 0 Adenylylsulphate kinase KTI12 PF08433.5 KFX87879.1 - 0.093 11.9 0.0 0.27 10.4 0.0 1.7 1 1 0 1 1 1 0 Chromatin associated protein KTI12 MIF4G_like PF09088.6 KFX87880.1 - 4.8e-84 280.5 0.0 7.5e-84 279.9 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 KFX87880.1 - 9.6e-51 172.4 0.0 1.6e-50 171.7 0.0 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 KFX87880.1 - 0.00055 19.4 0.0 0.0027 17.1 0.0 2.0 2 0 0 2 2 2 1 MIF4G domain Ribosomal_L5_C PF00673.16 KFX87881.1 - 2.9e-22 78.1 0.0 4.9e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KFX87881.1 - 1.2e-11 44.1 0.0 2e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 Fes1 PF08609.5 KFX87882.1 - 3.6e-11 43.3 3.0 3.6e-11 43.3 2.1 1.9 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 KFX87882.1 - 1.7e-09 37.8 0.1 9.6e-07 29.0 0.0 2.0 1 1 1 2 2 2 2 HEAT repeats Arm PF00514.18 KFX87882.1 - 6.1e-08 32.1 0.0 0.017 14.9 0.0 2.9 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KFX87882.1 - 2.9e-06 26.8 0.0 0.0078 16.2 0.0 3.4 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 KFX87882.1 - 2.3e-05 24.7 0.1 0.2 12.2 0.0 2.6 2 0 0 2 2 2 2 HEAT-like repeat Adaptin_N PF01602.15 KFX87882.1 - 0.057 11.7 0.1 5.7 5.1 0.0 2.0 2 0 0 2 2 2 0 Adaptin N terminal region S1 PF00575.18 KFX87887.1 - 3.9e-05 23.6 0.1 0.091 12.8 0.0 3.0 3 1 0 3 3 3 2 S1 RNA binding domain DOT1 PF08123.8 KFX87888.1 - 4.1e-72 241.7 0.1 6.1e-72 241.2 0.1 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 KFX87888.1 - 0.055 13.5 0.1 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ATG16 PF08614.6 KFX87889.1 - 5.1e-43 147.1 13.9 6.1e-43 146.9 9.6 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) YbbR PF07949.7 KFX87889.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 YbbR-like protein Scaffolding_pro PF11418.3 KFX87889.1 - 0.34 11.2 5.0 1.7 9.0 0.7 2.5 2 1 0 2 2 2 0 Phi29 scaffolding protein V_ATPase_I PF01496.14 KFX87889.1 - 1.1 7.0 4.8 1.6 6.4 3.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_1 PF00170.16 KFX87889.1 - 1.2 9.0 12.4 0.42 10.6 0.1 3.1 2 1 1 3 3 3 0 bZIP transcription factor zf-C4H2 PF10146.4 KFX87889.1 - 6.9 6.6 7.6 17 5.3 3.2 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein Ras PF00071.17 KFX87890.1 - 1.5e-56 190.2 0.1 1.7e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX87890.1 - 5.6e-19 68.7 0.0 8.4e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFX87890.1 - 8.7e-13 47.8 0.0 1e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFX87890.1 - 2.5e-07 30.6 0.0 3.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFX87890.1 - 4.1e-07 29.3 0.0 5.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFX87890.1 - 5.5e-07 29.1 0.0 2.2e-05 23.9 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KFX87890.1 - 0.00081 19.5 0.0 0.0012 18.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFX87890.1 - 0.0011 18.1 0.1 0.0023 17.1 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_5 PF07728.9 KFX87890.1 - 0.003 17.3 0.0 0.014 15.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 KFX87890.1 - 0.0047 16.5 0.2 0.0092 15.5 0.1 1.4 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KFX87890.1 - 0.0048 16.3 0.1 0.096 12.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 KFX87890.1 - 0.005 16.4 0.3 0.18 11.2 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 KFX87890.1 - 0.0064 16.2 0.2 0.013 15.2 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_10 PF12846.2 KFX87890.1 - 0.0083 15.6 0.2 0.012 15.0 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain SRPRB PF09439.5 KFX87890.1 - 0.0086 15.3 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.14 KFX87890.1 - 0.0091 15.4 0.0 0.04 13.3 0.0 1.8 1 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 KFX87890.1 - 0.0099 14.9 0.1 0.031 13.2 0.0 1.8 2 0 0 2 2 2 1 Septin AAA_16 PF13191.1 KFX87890.1 - 0.012 15.5 0.0 0.032 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 KFX87890.1 - 0.024 14.3 0.1 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 KFX87890.1 - 0.036 13.7 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 NTPase FeoB_N PF02421.13 KFX87890.1 - 0.071 12.3 0.0 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B NACHT PF05729.7 KFX87890.1 - 0.088 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DUF914 PF06027.7 KFX87891.1 - 2.3e-08 33.2 10.2 2.3e-08 33.2 7.1 2.1 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 KFX87891.1 - 3.2e-07 30.4 8.7 3.2e-07 30.4 6.0 3.3 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 KFX87891.1 - 1.2e-05 25.5 7.5 1.2e-05 25.5 5.2 3.3 3 1 0 3 3 3 1 Multidrug resistance efflux transporter UAA PF08449.6 KFX87891.1 - 1.9e-05 23.7 12.1 8.4e-05 21.6 7.6 1.9 2 0 0 2 2 2 1 UAA transporter family TPT PF03151.11 KFX87891.1 - 2e-05 24.2 29.2 0.00029 20.5 4.7 2.8 3 0 0 3 3 3 2 Triose-phosphate Transporter family Spb1_C PF07780.7 KFX87892.1 - 1.6e-76 256.5 9.7 1.6e-76 256.5 6.7 3.5 3 1 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 KFX87892.1 - 2.6e-57 192.7 6.0 2.6e-57 192.7 4.2 4.7 4 1 1 5 5 5 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 KFX87892.1 - 5.3e-54 182.9 0.1 1.1e-53 181.9 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 KFX87892.1 - 0.046 14.2 2.1 2.7 8.6 0.0 3.8 3 1 0 3 3 3 0 Methyltransferase domain WD40 PF00400.27 KFX87893.1 - 2.4e-21 74.7 7.3 2.6e-06 27.0 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Met_asp_mut_E PF06368.6 KFX87893.1 - 0.022 12.9 0.0 0.036 12.2 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Bim_N PF06773.6 KFX87893.1 - 3.9 7.3 10.0 0.35 10.6 1.2 3.3 3 0 0 3 3 3 0 Bim protein N-terminus DUF3328 PF11807.3 KFX87895.1 - 7e-13 48.7 0.8 7e-13 48.7 0.5 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) Cyclin_N PF00134.18 KFX87901.1 - 4.2e-42 142.6 0.0 7.4e-42 141.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFX87901.1 - 2.4e-33 114.5 0.0 5.8e-33 113.3 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Mito_carr PF00153.22 KFX87902.1 - 5.5e-75 247.1 1.0 7.1e-26 89.7 0.0 3.4 2 1 1 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 KFX87902.1 - 3.1e-16 57.3 6.3 4.5e-07 28.7 0.1 5.8 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.1 KFX87902.1 - 5e-15 55.3 4.2 6.1e-08 32.6 0.6 4.0 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 KFX87902.1 - 1.8e-14 52.2 6.3 5.8e-07 28.8 0.1 6.4 6 0 0 6 6 6 2 EF-hand domain EF-hand_5 PF13202.1 KFX87902.1 - 1.5e-10 39.8 3.1 1.2e-05 24.4 0.2 4.5 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.1 KFX87902.1 - 2.6e-10 39.7 7.0 0.1 12.2 0.0 5.7 5 1 1 6 6 6 5 EF-hand domain pair EF-hand_9 PF14658.1 KFX87902.1 - 0.13 12.2 0.0 16 5.5 0.0 3.8 4 0 0 4 4 4 0 EF-hand domain EF-hand_4 PF12763.2 KFX87902.1 - 0.21 11.3 0.2 2.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand p25-alpha PF05517.7 KFX87902.1 - 0.45 10.7 3.0 24 5.1 2.2 3.2 1 1 0 1 1 1 0 p25-alpha Chitin_synth_1 PF01644.12 KFX87906.1 - 5e-82 273.5 0.2 7.6e-82 272.9 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KFX87906.1 - 9.1e-31 105.3 0.0 1.8e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KFX87906.1 - 5.9e-21 74.4 5.6 3.3e-17 62.0 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KFX87906.1 - 1.7e-11 44.2 5.7 1.7e-11 44.2 3.9 2.7 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KFX87906.1 - 1.2e-09 38.2 0.0 5.1e-09 36.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Bac_export_2 PF01312.14 KFX87906.1 - 2.9 6.6 7.2 4.7 6.0 5.0 1.3 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family RNA_pol_L_2 PF13656.1 KFX87908.1 - 6.7e-32 108.7 0.0 9e-32 108.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KFX87908.1 - 1.5e-11 43.2 0.0 2.2e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR_2 PF13233.1 KFX87909.1 - 0.00056 20.3 0.3 0.00076 19.9 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KFX87909.1 - 0.0048 16.6 0.1 0.012 15.4 0.1 1.7 1 1 0 1 1 1 1 Complex 1 protein (LYR family) R-HINP1I PF11463.3 KFX87909.1 - 0.0088 15.4 1.2 0.13 11.6 0.1 2.0 1 1 1 2 2 2 1 R.HinP1I restriction endonuclease Complex1_LYR_1 PF13232.1 KFX87909.1 - 0.022 14.9 0.4 0.034 14.3 0.3 1.5 1 0 0 1 1 1 0 Complex1_LYR-like G10 PF01125.12 KFX87910.1 - 5.1e-56 188.2 6.4 5.7e-56 188.1 4.5 1.0 1 0 0 1 1 1 1 G10 protein DUF2721 PF11026.3 KFX87913.1 - 0.1 12.2 1.6 0.15 11.7 1.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) TMF_DNA_bd PF12329.3 KFX87913.1 - 4.3 7.2 6.1 7.9 6.3 0.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Glyco_hydro_76 PF03663.9 KFX87915.1 - 3e-133 444.7 13.1 3.8e-133 444.4 9.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KFX87915.1 - 0.53 9.2 9.4 0.22 10.5 0.6 2.9 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 ORC4_C PF14629.1 KFX87916.1 - 1.8e-53 181.0 0.0 3.2e-53 180.1 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 KFX87916.1 - 1.5e-18 67.4 0.5 1.5e-18 67.4 0.4 2.4 2 1 0 2 2 1 1 AAA ATPase domain PHD_2 PF13831.1 KFX87916.1 - 1.4e-11 43.4 2.2 2.9e-11 42.4 1.5 1.5 1 0 0 1 1 1 1 PHD-finger AAA_22 PF13401.1 KFX87916.1 - 1.8e-10 41.0 0.0 3.7e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain PHD PF00628.24 KFX87916.1 - 5e-10 38.9 6.9 8.5e-10 38.1 4.8 1.4 1 0 0 1 1 1 1 PHD-finger NACHT PF05729.7 KFX87916.1 - 3.6e-08 33.2 0.1 1.3e-07 31.4 0.1 1.9 1 1 0 1 1 1 1 NACHT domain AAA PF00004.24 KFX87916.1 - 2.9e-07 30.7 0.0 8.7e-07 29.2 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 KFX87916.1 - 0.00021 20.3 0.0 0.00033 19.7 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain Arch_ATPase PF01637.13 KFX87916.1 - 0.00022 20.9 0.0 0.00037 20.2 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 KFX87916.1 - 0.00056 19.8 0.0 0.0013 18.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KFX87916.1 - 0.00063 19.2 0.2 0.49 9.7 0.0 2.5 1 1 0 2 2 2 1 AAA-like domain DUF815 PF05673.8 KFX87916.1 - 0.00075 18.5 0.0 0.0013 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) MobB PF03205.9 KFX87916.1 - 0.00085 19.0 0.0 0.0024 17.5 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KFX87916.1 - 0.0011 18.5 0.0 0.0038 16.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFX87916.1 - 0.0012 18.3 0.0 0.0026 17.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NB-ARC PF00931.17 KFX87916.1 - 0.0012 17.7 0.1 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain ATP_bind_1 PF03029.12 KFX87916.1 - 0.0013 18.3 0.0 0.13 11.7 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 KFX87916.1 - 0.0019 17.6 0.0 0.0048 16.4 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_17 PF13207.1 KFX87916.1 - 0.002 18.9 0.0 0.017 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain C1_1 PF00130.17 KFX87916.1 - 0.0033 17.1 1.0 0.0033 17.1 0.7 1.8 1 1 1 2 2 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_33 PF13671.1 KFX87916.1 - 0.0045 16.8 0.6 0.014 15.2 0.1 2.1 2 1 0 2 2 1 1 AAA domain T2SE PF00437.15 KFX87916.1 - 0.0048 15.8 0.0 0.0078 15.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 KFX87916.1 - 0.0066 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Miro PF08477.8 KFX87916.1 - 0.01 16.3 0.0 0.03 14.8 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein cobW PF02492.14 KFX87916.1 - 0.019 14.4 0.0 0.047 13.1 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 KFX87916.1 - 0.024 14.3 0.0 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.1 KFX87916.1 - 0.029 13.7 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 KFX87916.1 - 0.031 13.2 0.0 0.063 12.2 0.0 1.4 2 0 0 2 2 1 0 PIF1-like helicase AAA_18 PF13238.1 KFX87916.1 - 0.055 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 KFX87916.1 - 0.056 12.8 0.0 0.53 9.6 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain FYVE_2 PF02318.11 KFX87916.1 - 0.066 13.1 1.1 0.14 12.0 0.8 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger ABC_tran PF00005.22 KFX87916.1 - 0.07 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 KFX87916.1 - 0.07 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 KFX87916.1 - 0.076 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 KFX87916.1 - 0.088 12.3 0.0 2.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 KFX87916.1 - 0.095 12.1 0.1 2.4 7.5 0.0 2.7 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_28 PF13521.1 KFX87916.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 KFX87916.1 - 0.12 11.8 0.2 2.8 7.4 0.1 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase AT_hook PF02178.14 KFX87916.1 - 4.7 7.2 46.6 0.13 11.9 2.6 4.9 5 0 0 5 5 3 0 AT hook motif CUE PF02845.11 KFX87918.1 - 5e-13 48.2 0.0 7.4e-13 47.7 0.0 1.3 1 0 0 1 1 1 1 CUE domain Kelch_4 PF13418.1 KFX87926.1 - 3.5e-33 113.1 12.2 1.1e-06 28.3 0.0 6.6 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 KFX87926.1 - 1.8e-31 107.5 9.7 8e-09 35.2 0.2 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 KFX87926.1 - 1.2e-28 98.6 20.4 5.6e-08 32.7 0.1 6.6 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.1 KFX87926.1 - 2e-28 97.3 9.0 1e-08 34.9 1.0 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.20 KFX87926.1 - 2e-26 91.2 6.1 3.1e-07 29.8 0.3 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.10 KFX87926.1 - 1.3e-19 69.1 10.0 2.8e-06 26.8 0.5 6.5 6 0 0 6 6 6 4 Kelch motif RAG2 PF03089.9 KFX87926.1 - 0.036 12.7 0.3 0.67 8.6 0.0 3.0 4 0 0 4 4 4 0 Recombination activating protein 2 LRR_4 PF12799.2 KFX87927.1 - 1.5e-08 34.0 6.2 3.5e-05 23.3 0.4 2.6 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFX87927.1 - 4.1e-08 32.8 1.1 1.2e-07 31.3 0.8 1.8 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 KFX87927.1 - 0.049 13.6 3.9 11 6.5 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 KFX87927.1 - 0.11 12.7 3.0 8 7.1 0.3 3.7 3 0 0 3 3 3 0 Leucine rich repeat Phosducin PF02114.11 KFX87928.1 - 2.8e-10 39.3 0.1 4.1e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 Phosducin alpha-hel2 PF14456.1 KFX87928.1 - 0.046 12.4 0.1 0.07 11.8 0.1 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 Ribosomal_S27e PF01667.12 KFX87929.1 - 5.9e-29 99.3 6.6 7.4e-29 99.0 4.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 KFX87929.1 - 0.0066 16.2 1.1 0.0077 16.0 0.8 1.2 1 0 0 1 1 1 1 IBR domain zf-CSL PF05207.8 KFX87929.1 - 0.1 12.0 0.5 0.19 11.2 0.4 1.5 1 0 0 1 1 1 0 CSL zinc finger VirE2 PF07229.7 KFX87932.1 - 1.4 7.2 10.6 1.4 7.1 7.4 1.0 1 0 0 1 1 1 0 VirE2 Prothymosin PF03247.9 KFX87932.1 - 1.6 8.9 15.3 4.7 7.4 10.6 1.7 1 1 0 1 1 1 0 Prothymosin/parathymosin family Pox_Ag35 PF03286.9 KFX87932.1 - 1.6 8.2 12.0 1.8 8.0 8.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Asp PF00026.18 KFX87933.1 - 9.4e-105 350.3 0.2 1.3e-104 349.9 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFX87933.1 - 7.6e-12 45.4 0.0 1.8e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Clp1 PF06807.9 KFX87933.1 - 4e-11 43.0 0.0 7.7e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 TAXi_C PF14541.1 KFX87933.1 - 0.00016 21.2 0.0 0.00089 18.8 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KFX87933.1 - 0.00069 20.0 0.1 1.3 9.6 0.0 3.1 2 1 0 2 2 2 2 Aspartyl protease AAA_10 PF12846.2 KFX87933.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.9 KFX87933.1 - 0.019 14.7 0.0 0.062 12.9 0.0 1.9 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KFX87933.1 - 0.026 15.3 0.0 0.11 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KFX87933.1 - 0.037 14.1 0.0 0.084 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFX87933.1 - 0.053 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFX87933.1 - 0.12 12.5 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Alpha-amylase_C PF02806.13 KFX87933.1 - 0.17 12.0 0.1 1.1 9.4 0.0 2.4 3 0 0 3 3 3 0 Alpha amylase, C-terminal all-beta domain PV-1 PF06637.6 KFX87943.1 - 0.3 9.6 1.4 0.4 9.1 0.9 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) WD40 PF00400.27 KFX87947.1 - 1.3e-68 224.6 13.1 7.2e-11 41.5 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 KFX87947.1 - 2.4e-27 94.9 5.8 3.7e-27 94.3 4.0 1.3 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 KFX87947.1 - 0.0026 15.9 0.1 0.38 8.8 0.0 2.7 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 KFX87947.1 - 0.0048 16.0 0.0 2.5 7.1 0.0 2.8 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 KFX87947.1 - 0.0061 15.3 0.2 0.69 8.5 0.1 2.8 1 1 3 4 4 4 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 KFX87947.1 - 0.063 11.5 0.7 0.6 8.3 0.3 2.3 1 1 1 2 2 2 0 Cytochrome D1 heme domain DUF3037 PF11236.3 KFX87947.1 - 0.2 11.7 0.2 0.38 10.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3037) zf-UBP PF02148.14 KFX87949.1 - 4.2e-17 62.0 5.5 3.7e-16 58.9 4.4 1.9 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Tropomyosin_1 PF12718.2 KFX87949.1 - 0.0079 16.0 5.8 0.0079 16.0 4.0 2.2 1 1 1 2 2 2 1 Tropomyosin like DUF3128 PF11326.3 KFX87949.1 - 0.089 12.9 0.0 0.38 10.9 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) Tup_N PF08581.5 KFX87949.1 - 0.17 12.0 5.8 4.3 7.5 0.9 2.6 2 0 0 2 2 2 0 Tup N-terminal Adeno_PIX PF03955.9 KFX87949.1 - 0.18 12.3 3.0 12 6.4 0.1 2.6 1 1 2 3 3 3 0 Adenovirus hexon-associated protein (IX) CENP-F_leu_zip PF10473.4 KFX87949.1 - 0.86 9.4 15.4 1.6 8.5 9.4 2.2 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 KFX87949.1 - 1.9 8.8 7.4 0.8 10.0 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Cep57_CLD_2 PF14197.1 KFX87949.1 - 2.6 8.0 9.9 2.4 8.1 1.6 2.6 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DivIVA PF05103.8 KFX87949.1 - 3.1 7.8 9.0 2.5 8.1 0.3 2.5 2 1 1 3 3 3 0 DivIVA protein YkyA PF10368.4 KFX87949.1 - 4.3 6.6 9.0 6.7 5.9 6.2 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Seryl_tRNA_N PF02403.17 KFX87949.1 - 5.3 7.0 9.6 8.8 6.3 0.9 2.6 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Zn_clus PF00172.13 KFX87957.1 - 3.8e-07 29.8 9.7 6.6e-07 29.1 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFX87957.1 - 1e-06 27.5 0.2 1.5e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 KFX87961.1 - 2.4e-15 56.0 0.9 3.9e-15 55.3 0.4 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain DLH PF01738.13 KFX87962.1 - 7.2e-16 58.1 0.0 7.9e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFX87962.1 - 2.8e-07 30.4 0.0 3.9e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AMP-binding PF00501.23 KFX87963.1 - 1.2e-74 251.2 0.0 3.1e-74 249.8 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KFX87963.1 - 9.1e-71 237.6 0.0 1.3e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KFX87963.1 - 3.9e-13 49.3 0.0 7.4e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KFX87963.1 - 2e-09 37.5 0.0 4.3e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KFX87963.1 - 1.6e-08 33.5 0.1 4.3e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 KFX87963.1 - 4e-06 27.6 0.0 2.5e-05 25.1 0.0 2.5 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain adh_short PF00106.20 KFX87963.1 - 0.008 16.1 0.5 0.027 14.3 0.3 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KFX87963.1 - 0.033 13.1 0.0 0.079 11.8 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KFX87963.1 - 0.087 11.7 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain OapA_N PF08525.6 KFX87969.1 - 0.81 9.5 3.9 0.71 9.7 1.0 2.0 2 0 0 2 2 2 0 Opacity-associated protein A N-terminal motif OPT PF03169.10 KFX87977.1 - 2.7e-181 604.2 22.4 3.1e-181 603.9 15.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Gly-zipper_OmpA PF13436.1 KFX87980.1 - 4.7 6.8 18.6 0.61 9.7 5.9 2.5 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Zip PF02535.17 KFX87989.1 - 2.1e-17 63.1 3.2 3e-17 62.6 2.2 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2040 PF09745.4 KFX87990.1 - 9.8e-37 125.6 16.8 9.8e-37 125.6 11.6 3.1 2 1 1 3 3 3 2 Coiled-coil domain-containing protein 55 (DUF2040) Neogenin_C PF06583.7 KFX87992.1 - 0.015 14.9 5.1 0.017 14.6 3.5 1.0 1 0 0 1 1 1 0 Neogenin C-terminus RINGv PF12906.2 KFX87993.1 - 7.2e-09 35.5 4.6 7.9e-09 35.4 0.6 2.2 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 KFX87993.1 - 0.023 14.5 1.5 0.023 14.5 1.1 2.1 2 0 0 2 2 2 0 Ring finger domain Xan_ur_permease PF00860.15 KFX87993.1 - 0.068 11.6 0.2 0.29 9.5 0.0 1.8 2 0 0 2 2 2 0 Permease family Proteasome PF00227.21 KFX87994.1 - 5.9e-57 192.0 0.0 6.1e-33 113.7 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 KFX87994.1 - 1.7e-11 43.2 0.4 3.5e-11 42.2 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature WD40 PF00400.27 KFX87995.1 - 1.4e-08 34.2 17.5 3.9e-06 26.5 0.4 5.7 7 0 0 7 7 7 4 WD domain, G-beta repeat PQQ PF01011.16 KFX87995.1 - 4.8e-06 25.8 1.5 0.61 9.7 0.2 3.7 3 0 0 3 3 3 3 PQQ enzyme repeat DUF1399 PF07173.7 KFX87996.1 - 3.5e-20 72.6 6.3 7.3e-14 52.2 0.1 4.8 2 2 2 4 4 4 4 Protein of unknown function (DUF1399) IncA PF04156.9 KFX87996.1 - 0.11 12.0 2.7 0.21 11.1 1.9 1.5 1 0 0 1 1 1 0 IncA protein PXT1 PF15214.1 KFX87996.1 - 0.14 12.4 1.1 25 5.2 0.0 3.2 3 0 0 3 3 3 0 Peroxisomal testis-specific protein 1 MFS_1 PF07690.11 KFX87997.1 - 2.9e-30 105.1 30.6 5.9e-29 100.8 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Lipase_GDSL_2 PF13472.1 KFX87998.1 - 1.4e-21 77.4 0.0 1.7e-21 77.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFX87998.1 - 5.5e-16 59.0 0.0 8e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Cellulase PF00150.13 KFX88006.1 - 1.3e-08 34.3 0.2 1.3e-08 34.3 0.1 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Carb_bind PF10645.4 KFX88006.1 - 0.05 13.4 1.0 1.2 8.9 0.4 2.7 3 0 0 3 3 3 0 Carbohydrate binding DUF1510 PF07423.6 KFX88006.1 - 0.071 12.4 0.0 0.071 12.4 0.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1510) DUF515 PF04415.7 KFX88006.1 - 0.19 9.9 0.3 0.32 9.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) OAD_gamma PF04277.8 KFX88006.1 - 1.3 9.4 3.3 12 6.3 0.0 2.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Transket_pyr PF02779.19 KFX88007.1 - 1.7e-42 144.9 0.0 2.6e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KFX88007.1 - 6.3e-32 110.1 0.0 1.4e-31 108.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain MAPEG PF01124.13 KFX88010.1 - 1.9e-12 46.8 3.7 2.4e-12 46.6 2.5 1.1 1 0 0 1 1 1 1 MAPEG family CD99L2 PF12301.3 KFX88013.1 - 1.8 8.1 4.9 1.9 8.1 3.4 1.0 1 0 0 1 1 1 0 CD99 antigen like protein 2 ADH_N PF08240.7 KFX88014.1 - 5.7e-28 96.8 1.9 5.7e-28 96.8 1.3 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX88014.1 - 1.9e-19 69.4 0.3 3.9e-19 68.4 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MobB PF03205.9 KFX88014.1 - 0.0096 15.6 0.2 2.9 7.5 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Pyr_redox_3 PF13738.1 KFX88014.1 - 0.09 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KFX88014.1 - 0.098 12.9 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.16 KFX88014.1 - 0.11 12.3 3.6 0.96 9.2 1.7 2.3 2 0 0 2 2 2 0 ThiF family ELFV_dehydrog PF00208.16 KFX88014.1 - 0.23 11.0 2.5 0.4 10.2 1.8 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Zn_clus PF00172.13 KFX88015.1 - 2.6e-06 27.2 13.9 4.8e-06 26.3 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2TM PF13239.1 KFX88016.1 - 0.024 14.6 3.2 0.059 13.4 0.3 2.4 2 0 0 2 2 2 0 2TM domain DUF1352 PF07086.7 KFX88016.1 - 0.37 10.4 3.4 1.2 8.7 2.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1352) Amidase PF01425.16 KFX88022.1 - 5e-11 42.1 0.2 6e-11 41.8 0.1 1.1 1 0 0 1 1 1 1 Amidase DnaJ PF00226.26 KFX88023.1 - 1.9e-19 69.1 1.2 1.9e-19 69.1 0.8 2.4 2 1 0 2 2 2 1 DnaJ domain DUF4551 PF15087.1 KFX88023.1 - 0.13 10.6 9.8 0.22 9.8 6.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) PspB PF06667.7 KFX88023.1 - 0.16 11.9 1.3 0.48 10.3 0.9 1.8 1 0 0 1 1 1 0 Phage shock protein B Complex1_LYR PF05347.10 KFX88024.1 - 1.2e-06 28.2 0.3 1.9e-06 27.5 0.1 1.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFX88024.1 - 6.4e-05 23.0 0.1 7.5e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Abhydrolase_3 PF07859.8 KFX88025.1 - 1.5e-16 60.6 0.1 1.1e-14 54.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFX88025.1 - 5.3e-12 45.4 0.0 4.2e-05 22.8 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFX88025.1 - 7.6e-10 38.7 0.0 4.7e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX88025.1 - 3.2e-08 33.7 2.0 5.1e-08 33.0 1.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KFX88025.1 - 0.034 13.4 0.0 4 6.6 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family GDA1_CD39 PF01150.12 KFX88030.1 - 2.3e-13 49.4 0.0 3.1e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family PBP1_TM PF14812.1 KFX88045.1 - 0.8 10.0 4.6 1.3 9.4 3.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Inp1 PF12634.2 KFX88052.1 - 6.6e-31 106.9 0.0 1.5e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 Mog1 PF04603.7 KFX88053.1 - 1.1e-20 74.0 0.0 1.5e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Acetyltransf_7 PF13508.1 KFX88054.1 - 2.4e-07 30.8 0.0 8.6e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX88054.1 - 2.8e-06 27.2 0.0 5.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KFX88054.1 - 0.0018 17.9 0.0 0.0045 16.7 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KFX88054.1 - 0.0025 17.9 0.0 0.028 14.5 0.0 2.3 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFX88054.1 - 0.022 14.5 0.0 0.098 12.5 0.0 2.1 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF1643 PF07799.7 KFX88054.1 - 0.11 12.2 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) MAGE_N PF12440.3 KFX88057.1 - 0.34 11.2 0.2 0.34 11.2 0.1 2.1 1 1 1 2 2 2 0 Melanoma associated antigen family N terminal DEC-1_N PF04625.8 KFX88057.1 - 1.3 7.6 8.7 1.4 7.5 6.1 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DUF1180 PF06679.7 KFX88057.1 - 4.7 7.0 6.1 5.4 6.8 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CAP_N PF01213.14 KFX88057.1 - 8.5 5.5 8.0 8.6 5.5 5.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RNA12 PF10443.4 KFX88058.1 - 1.1e-161 538.1 0.9 1.7e-161 537.5 0.6 1.3 1 0 0 1 1 1 1 RNA12 protein RRM_1 PF00076.17 KFX88058.1 - 0.00057 19.4 0.0 0.0064 16.1 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 KFX88058.1 - 0.0017 18.1 0.0 0.0045 16.7 0.0 1.8 1 1 0 1 1 1 1 Archaeal ATPase RRM_5 PF13893.1 KFX88058.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_14 PF13173.1 KFX88058.1 - 0.11 12.3 0.1 0.91 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain SicP-binding PF09119.5 KFX88059.1 - 0.0014 18.2 0.0 0.0029 17.2 0.0 1.5 1 0 0 1 1 1 1 SicP binding Usp PF00582.21 KFX88060.1 - 1.3 9.1 4.2 4 7.6 2.9 1.9 1 1 0 1 1 1 0 Universal stress protein family Peroxin-3 PF04882.7 KFX88061.1 - 4.4e-148 493.5 0.0 5.1e-148 493.3 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 Sybindin PF04099.7 KFX88062.1 - 2.5e-26 92.0 0.0 3.1e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KFX88062.1 - 0.01 15.7 0.1 0.014 15.2 0.1 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region FAD_binding_3 PF01494.14 KFX88070.1 - 1.8e-73 247.6 0.0 2.3e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KFX88070.1 - 2e-41 141.4 0.0 3.2e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 KFX88070.1 - 0.00064 20.0 0.0 0.018 15.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFX88070.1 - 0.0059 15.5 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KFX88070.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFX88070.1 - 0.015 15.1 0.0 0.048 13.5 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFX88070.1 - 0.026 13.6 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family XdhC_C PF13478.1 KFX88070.1 - 0.034 14.4 0.0 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain DAO PF01266.19 KFX88070.1 - 0.037 12.9 0.0 0.2 10.5 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.11 KFX88070.1 - 0.038 13.4 0.0 0.082 12.3 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 KFX88070.1 - 0.094 12.0 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF3337 PF11816.3 KFX88071.1 - 6.8e-84 282.0 0.2 5e-80 269.3 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF3337) DDHD PF02862.12 KFX88071.1 - 6.8e-29 101.2 13.8 2.6e-27 96.1 0.0 4.4 4 2 1 5 5 5 2 DDHD domain WD40 PF00400.27 KFX88071.1 - 2.1e-27 93.9 9.6 3.9e-07 29.7 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Lectin_leg-like PF03388.8 KFX88073.1 - 1.7e-66 223.6 0.0 2.4e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 KFX88073.1 - 0.0022 17.4 0.0 0.5 9.6 0.0 2.7 3 0 0 3 3 3 2 Legume lectin domain ATG27 PF09451.5 KFX88073.1 - 0.0076 15.5 0.1 0.0089 15.2 0.1 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 zf-Tim10_DDP PF02953.10 KFX88074.1 - 1.2e-23 82.1 2.6 1.4e-23 81.9 1.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Abhydrolase_4 PF08386.5 KFX88074.1 - 0.07 13.0 0.0 0.81 9.6 0.0 2.1 1 1 0 1 1 1 0 TAP-like protein adh_short PF00106.20 KFX88080.1 - 8e-29 100.6 8.3 1.6e-28 99.6 5.7 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX88080.1 - 3e-10 40.0 7.5 5e-09 36.0 5.2 2.2 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFX88080.1 - 5.7e-10 39.3 0.0 7.8e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase OGFr_N PF04664.8 KFX88081.1 - 6.3e-08 32.2 1.3 0.0012 18.2 0.0 2.7 3 0 0 3 3 3 2 Opioid growth factor receptor (OGFr) conserved region N6-adenineMlase PF10237.4 KFX88081.1 - 0.088 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase Oxysterol_BP PF01237.13 KFX88084.1 - 1.9e-88 296.3 0.0 2.5e-88 295.9 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein PCI PF01399.22 KFX88086.1 - 2.5e-11 43.8 0.0 7.9e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 PCI domain F-box-like PF12937.2 KFX88086.1 - 0.00071 19.2 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like RPN7 PF10602.4 KFX88086.1 - 0.0012 18.2 0.1 0.0024 17.2 0.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_19 PF14559.1 KFX88086.1 - 0.0071 16.6 0.7 0.3 11.4 0.4 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat DUF3138 PF11336.3 KFX88098.1 - 0.047 11.8 5.1 0.056 11.6 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) EthD PF07110.6 KFX88100.1 - 2e-10 41.4 0.4 3.8e-10 40.5 0.3 1.5 1 1 0 1 1 1 1 EthD domain LMBR1 PF04791.11 KFX88119.1 - 5.4e-29 101.1 12.4 1.6e-28 99.5 8.6 1.7 1 1 0 1 1 1 1 LMBR1-like membrane protein IncA PF04156.9 KFX88119.1 - 4.9e-05 23.0 0.1 4.9e-05 23.0 0.1 2.2 2 0 0 2 2 2 1 IncA protein DUF1515 PF07439.6 KFX88119.1 - 0.59 9.9 4.2 2 8.2 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) DUF2304 PF10066.4 KFX88119.1 - 0.7 9.7 6.6 1.3 8.8 0.3 3.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Methyltransf_16 PF10294.4 KFX88120.1 - 2.8e-18 65.9 0.0 3.9e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KFX88120.1 - 1.7e-11 44.7 0.0 4.6e-11 43.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX88120.1 - 0.00014 21.6 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX88120.1 - 0.0014 18.0 0.0 0.01 15.1 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KFX88120.1 - 0.0015 18.5 0.1 0.0043 17.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFX88120.1 - 0.004 16.3 0.0 0.0056 15.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 KFX88120.1 - 0.0061 16.1 0.0 0.023 14.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KFX88120.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_11 PF08241.7 KFX88120.1 - 0.022 15.2 0.0 0.074 13.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KFX88120.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Myb_DNA-binding PF00249.26 KFX88133.1 - 1.8e-22 79.1 0.6 1e-10 41.4 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFX88133.1 - 1.4e-17 63.5 1.0 7.6e-12 45.1 0.0 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.7 KFX88133.1 - 0.06 12.8 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_23 PF13384.1 KFX88133.1 - 0.079 12.6 0.9 0.14 11.8 0.1 1.8 2 0 0 2 2 2 0 Homeodomain-like domain TPR_11 PF13414.1 KFX88135.1 - 7.1e-32 108.8 11.7 8.7e-14 50.9 0.5 5.0 3 2 2 5 5 5 5 TPR repeat TPR_1 PF00515.23 KFX88135.1 - 3.8e-24 83.2 9.9 0.00014 21.3 0.0 7.3 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 KFX88135.1 - 5.3e-19 66.5 13.9 0.0018 18.0 0.1 7.3 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFX88135.1 - 1.8e-11 44.3 6.8 0.002 18.7 0.1 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 KFX88135.1 - 1.1e-09 37.9 4.7 9.4e-05 22.1 0.3 3.9 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFX88135.1 - 3.1e-09 36.3 6.5 0.69 10.2 0.5 5.7 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFX88135.1 - 3.8e-09 36.3 12.9 0.017 15.0 0.1 4.3 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 KFX88135.1 - 3e-06 26.6 1.4 1.7 8.6 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFX88135.1 - 1.7e-05 24.2 6.4 0.78 9.6 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFX88135.1 - 0.00033 21.0 6.0 0.44 11.3 0.1 4.6 5 1 0 5 5 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KFX88135.1 - 0.00037 20.5 8.6 0.35 11.0 0.1 3.2 2 2 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KFX88135.1 - 0.00059 18.9 0.9 0.3 10.0 0.1 3.1 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFX88135.1 - 0.0011 19.3 4.4 3.2 8.1 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat BLVR PF06375.6 KFX88135.1 - 0.0036 17.1 1.1 0.0064 16.3 0.8 1.4 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) SpoIIIAH PF12685.2 KFX88135.1 - 0.65 9.4 5.6 0.47 9.9 1.6 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein SHNi-TPR PF10516.4 KFX88135.1 - 2.7 7.3 11.3 38 3.6 0.0 5.3 6 0 0 6 6 6 0 SHNi-TPR TPR_6 PF13174.1 KFX88135.1 - 9.4 6.9 8.3 46 4.7 0.1 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF3455 PF11937.3 KFX88136.1 - 9.1e-34 116.9 0.0 1.1e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Ecl1 PF12855.2 KFX88157.1 - 1.3e-07 30.7 3.4 2.2e-07 30.0 2.3 1.4 1 0 0 1 1 1 1 Life-span regulatory factor DUF605 PF04652.11 KFX88157.1 - 0.67 9.2 10.3 0.74 9.1 7.1 1.1 1 0 0 1 1 1 0 Vta1 like NAD_binding_1 PF00175.16 KFX88160.1 - 4.5e-09 36.8 0.0 5.9e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KFX88160.1 - 8.4e-07 29.0 0.0 1.7e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KFX88160.1 - 0.0039 17.1 0.0 0.0066 16.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DnaJ PF00226.26 KFX88161.1 - 5.5e-21 74.0 0.4 9.2e-21 73.3 0.3 1.4 1 0 0 1 1 1 1 DnaJ domain Abhydrolase_6 PF12697.2 KFX88164.1 - 4.7e-11 43.0 0.0 7.1e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX88164.1 - 9.1e-10 38.4 0.0 1.3e-09 37.9 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFX88164.1 - 0.071 12.3 0.1 0.18 10.9 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family PNRC PF15365.1 KFX88164.1 - 0.14 12.1 0.8 0.36 10.8 0.5 1.7 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator HNH_2 PF13391.1 KFX88165.1 - 1.4e-13 50.4 0.0 3.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Mpv17_PMP22 PF04117.7 KFX88168.1 - 1.2e-15 56.8 0.2 1.2e-15 56.8 0.1 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family NQR2_RnfD_RnfE PF03116.10 KFX88168.1 - 0.017 14.2 0.3 0.022 13.9 0.2 1.1 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family Glyco_transf_22 PF03901.12 KFX88169.1 - 6.4e-79 265.8 12.7 7.6e-79 265.6 8.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family SNF5 PF04855.7 KFX88176.1 - 4.8e-70 235.7 0.1 9.3e-70 234.8 0.1 1.4 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Peptidase_M24 PF00557.19 KFX88177.1 - 1.2e-10 41.3 0.0 1.5e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 TIP41 PF04176.8 KFX88178.1 - 3e-73 244.9 0.2 4e-73 244.5 0.1 1.1 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.20 KFX88179.1 - 7.2e-72 241.6 0.0 8.8e-72 241.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX88179.1 - 1.4e-42 145.5 0.0 1.8e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX88179.1 - 2.7e-06 26.5 0.0 2e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFX88179.1 - 0.00097 18.2 0.1 0.0016 17.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFX88179.1 - 0.0046 16.3 0.0 0.0085 15.4 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 KFX88179.1 - 0.0076 15.6 0.0 0.077 12.3 0.0 2.0 1 1 1 2 2 2 1 RIO1 family APH PF01636.18 KFX88179.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M76 PF09768.4 KFX88180.1 - 1.6e-69 232.7 2.9 2.2e-69 232.3 2.0 1.2 1 0 0 1 1 1 1 Peptidase M76 family Tox-MPTase2 PF15638.1 KFX88180.1 - 0.02 14.4 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 2 zf-CW PF07496.10 KFX88180.1 - 0.026 14.2 0.7 1.2 8.9 0.1 2.6 2 0 0 2 2 2 0 CW-type Zinc Finger Peptidase_S10 PF00450.17 KFX88180.1 - 0.053 12.6 0.1 0.06 12.5 0.1 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase DUF2268 PF10026.4 KFX88180.1 - 0.061 12.6 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) SprT-like PF10263.4 KFX88180.1 - 0.073 12.7 6.8 0.032 13.8 2.1 2.3 2 1 0 2 2 2 0 SprT-like family Dicty_spore_N PF04562.7 KFX88180.1 - 0.1 12.8 1.8 0.31 11.3 0.6 2.2 1 1 1 2 2 2 0 Dictyostelium spore coat protein, N terminus AA_kinase PF00696.23 KFX88181.1 - 4.9e-40 137.5 2.2 7.6e-40 136.9 1.5 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 KFX88181.1 - 2.5e-13 49.5 2.2 1.1e-07 31.4 0.2 2.9 3 0 0 3 3 3 2 PUA domain RRN9 PF10680.4 KFX88187.1 - 1.6e-13 50.1 0.2 1.6e-13 50.1 0.1 2.0 2 1 0 2 2 2 1 RNA polymerase I specific transcription initiation factor Pescadillo_N PF06732.6 KFX88188.1 - 1.6e-110 368.8 0.1 1.6e-110 368.8 0.0 1.8 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 KFX88188.1 - 2.5e-10 40.3 0.0 1.5e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PIG-U PF06728.8 KFX88189.1 - 6.1e-125 417.0 30.4 7.1e-125 416.8 21.1 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF1708 PF08101.6 KFX88193.1 - 4.8e-152 506.6 0.0 5.9e-152 506.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) 2OG-FeII_Oxy_2 PF13532.1 KFX88196.1 - 4.5e-25 88.6 0.0 5.8e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 KFX88196.1 - 0.0016 18.3 3.8 0.0027 17.5 2.6 1.3 1 0 0 1 1 1 1 GRF zinc finger 2OG-FeII_Oxy PF03171.15 KFX88196.1 - 0.032 14.5 0.0 0.057 13.7 0.0 1.4 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily NicO PF03824.11 KFX88197.1 - 6.5e-44 150.3 7.8 7.6e-44 150.1 5.4 1.0 1 0 0 1 1 1 1 High-affinity nickel-transport protein DUF3583 PF12126.3 KFX88205.1 - 0.18 10.8 1.3 0.2 10.7 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) DUF1509 PF07420.6 KFX88205.1 - 0.28 10.4 2.7 0.31 10.2 1.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) zf-C2H2_3 PF13878.1 KFX88210.1 - 4.2e-08 32.6 0.1 7.1e-08 31.8 0.1 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO polyprenyl_synt PF00348.12 KFX88211.1 - 1.7e-54 184.3 0.0 7.8e-52 175.6 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 KFX88211.1 - 0.0069 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Milton PF12448.3 KFX88211.1 - 0.83 9.8 7.5 3.8 7.6 0.4 2.3 2 0 0 2 2 2 0 Kinesin associated protein Vma12 PF11712.3 KFX88212.1 - 9.3e-39 132.3 0.0 1.6e-38 131.5 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3989 PF13150.1 KFX88212.1 - 0.17 11.3 0.3 0.46 9.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) JAB PF01398.16 KFX88214.1 - 5.2e-15 55.1 0.0 8.8e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 KFX88214.1 - 2e-08 34.1 0.0 3.7e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 KFX88214.1 - 3.5e-06 26.5 0.1 1.3e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain RrnaAD PF00398.15 KFX88215.1 - 0.0094 15.0 0.0 0.013 14.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase FAST_1 PF06743.10 KFX88217.1 - 0.088 12.5 0.1 6.4 6.5 0.0 2.4 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 GLTT PF01744.15 KFX88219.1 - 0.002 17.4 1.5 0.002 17.4 1.1 2.5 1 1 1 2 2 2 1 GLTT repeat (6 copies) BAF1_ABF1 PF04684.8 KFX88219.1 - 0.31 9.8 1.9 0.43 9.3 1.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Ribonuc_red_lgC PF02867.10 KFX88220.1 - 9.3e-95 318.1 0.0 1.2e-94 317.8 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain SET PF00856.23 KFX88221.1 - 1.1e-12 48.5 0.0 5.2e-10 39.8 0.0 2.1 1 1 0 1 1 1 1 SET domain DUF3723 PF12520.3 KFX88223.1 - 2.8e-16 59.1 0.0 2.8e-16 59.1 0.0 2.4 2 1 0 2 2 1 1 Protein of unknown function (DUF3723) Nop14 PF04147.7 KFX88223.1 - 0.0016 16.4 26.5 0.0021 16.0 18.4 1.1 1 0 0 1 1 1 1 Nop14-like family CAF-1_p150 PF11600.3 KFX88223.1 - 0.005 16.2 27.4 0.009 15.4 19.0 1.4 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1510 PF07423.6 KFX88223.1 - 0.022 14.1 28.8 0.035 13.4 20.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SAPS PF04499.10 KFX88223.1 - 0.023 13.3 12.1 0.027 13.1 8.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Daxx PF03344.10 KFX88223.1 - 0.075 11.5 30.7 0.099 11.1 21.3 1.1 1 0 0 1 1 1 0 Daxx Family DHHW PF14286.1 KFX88223.1 - 0.092 12.0 8.1 0.13 11.5 5.6 1.2 1 0 0 1 1 1 0 DHHW protein SprA-related PF12118.3 KFX88223.1 - 0.16 11.3 29.5 0.22 10.8 20.4 1.2 1 0 0 1 1 1 0 SprA-related family Raftlin PF15250.1 KFX88223.1 - 0.29 9.5 11.3 0.37 9.2 7.8 1.2 1 0 0 1 1 1 0 Raftlin Mem_trans PF03547.13 KFX88223.1 - 0.31 9.2 5.6 0.52 8.5 3.9 1.4 1 0 0 1 1 1 0 Membrane transport protein Spore_coat_CotO PF14153.1 KFX88223.1 - 0.33 10.3 23.4 0.52 9.7 16.2 1.4 1 0 0 1 1 1 0 Spore coat protein CotO GAGA_bind PF06217.7 KFX88223.1 - 0.62 9.9 12.7 0.79 9.6 8.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family CobT PF06213.7 KFX88223.1 - 1.6 7.7 28.3 2.7 7.0 19.6 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Parvo_coat PF00740.13 KFX88223.1 - 2.9 6.7 13.2 3.5 6.4 9.2 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 Zip PF02535.17 KFX88223.1 - 3.6 6.4 7.8 5.8 5.8 5.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter LMBR1 PF04791.11 KFX88223.1 - 3.7 6.0 8.5 4.7 5.6 5.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Hid1 PF12722.2 KFX88223.1 - 4.7 4.7 18.5 5.7 4.4 12.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PPP4R2 PF09184.6 KFX88223.1 - 6.6 6.1 25.0 9.7 5.6 17.3 1.3 1 0 0 1 1 1 0 PPP4R2 Med15 PF09606.5 KFX88223.1 - 6.8 4.7 24.5 8.6 4.4 17.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RR_TM4-6 PF06459.7 KFX88223.1 - 6.9 6.4 20.7 9.6 6.0 14.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4175 PF13779.1 KFX88223.1 - 7.5 4.1 37.9 10 3.6 26.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Vfa1 PF08432.5 KFX88223.1 - 8.7 6.3 22.8 14 5.6 15.8 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 GCFC PF07842.7 KFX88226.1 - 1.5e-78 263.9 4.0 1.5e-78 263.9 2.8 1.6 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 KFX88226.1 - 2.5e-15 55.9 4.5 8.7e-15 54.2 3.1 2.0 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.3 KFX88226.1 - 3.1e-13 49.7 8.8 3.1e-13 49.7 6.1 2.7 2 1 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.2 KFX88226.1 - 9.8e-08 31.7 2.5 9.8e-08 31.7 1.7 2.6 2 2 0 2 2 2 1 DExH-box splicing factor binding site ATP-synt_E PF05680.7 KFX88226.1 - 4 7.4 7.9 0.82 9.6 1.5 2.5 2 0 0 2 2 2 0 ATP synthase E chain PH PF00169.24 KFX88229.1 - 1.6e-08 34.6 0.0 5.5e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 PH domain GRAM PF02893.15 KFX88229.1 - 0.0011 18.4 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 GRAM domain DUF3812 PF12757.2 KFX88230.1 - 9.4e-29 99.9 9.4 9.4e-29 99.9 6.5 4.2 4 1 1 5 5 5 1 Protein of unknown function (DUF3812) DUF2743 PF10899.3 KFX88230.1 - 0.31 10.3 7.0 0.66 9.3 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2743) F-box PF00646.28 KFX88233.1 - 0.0001 21.8 0.0 0.00026 20.5 0.0 1.7 1 0 0 1 1 1 1 F-box domain ketoacyl-synt PF00109.21 KFX88233.1 - 0.11 11.9 0.1 0.57 9.6 0.0 2.0 2 1 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain APH PF01636.18 KFX88234.1 - 2e-06 27.7 0.2 0.00018 21.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.6 KFX88234.1 - 0.00012 21.3 0.0 0.00018 20.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.17 KFX88234.1 - 0.00015 21.1 0.0 0.0003 20.1 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KFX88234.1 - 0.00076 18.6 0.1 0.0032 16.5 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KFX88234.1 - 0.0031 16.7 0.1 0.0074 15.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Cytochrom_D1 PF02239.11 KFX88234.1 - 0.014 13.6 0.0 0.023 12.9 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Seadorna_VP7 PF07387.6 KFX88234.1 - 0.03 13.1 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Hydrolase_6 PF13344.1 KFX88235.1 - 1.5e-22 79.3 0.0 2.7e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFX88235.1 - 9.3e-12 44.4 0.0 1.2e-10 40.9 0.0 2.4 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 KFX88235.1 - 0.0079 16.4 0.0 2.7 8.1 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFX88235.1 - 0.11 12.8 0.0 1.6 9.0 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Peptidase_M74 PF03411.8 KFX88238.1 - 0.058 12.6 0.0 0.064 12.4 0.0 1.1 1 0 0 1 1 1 0 Penicillin-insensitive murein endopeptidase DUF1794 PF08768.6 KFX88238.1 - 0.085 12.7 0.1 0.26 11.1 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1794) IDO PF01231.13 KFX88239.1 - 9.3e-47 159.3 0.0 1.3e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Lactamase_B PF00753.22 KFX88240.1 - 5.3e-08 32.7 0.0 8.8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFX88240.1 - 4.7e-05 23.0 0.0 5.6e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PAP_assoc PF03828.14 KFX88243.1 - 2.6e-19 68.9 0.1 5.3e-19 67.9 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KFX88243.1 - 7.3e-06 26.2 0.0 1.4e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain NUC153 PF08159.7 KFX88246.1 - 4.4e-14 51.7 2.2 8.3e-14 50.8 1.5 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 KFX88246.1 - 1.9e-05 24.3 0.2 0.0029 17.4 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat Noc2 PF03715.8 KFX88247.1 - 2.8e-117 390.8 0.0 8.4e-117 389.2 0.0 1.8 2 0 0 2 2 2 1 Noc2p family DUF4477 PF14780.1 KFX88247.1 - 0.076 12.3 0.3 0.15 11.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4477) VPS28 PF03997.7 KFX88248.1 - 8.4e-56 188.5 0.1 9.9e-56 188.3 0.1 1.0 1 0 0 1 1 1 1 VPS28 protein GvpG PF05120.7 KFX88248.1 - 0.013 15.3 2.5 2.5 7.9 0.2 2.3 2 0 0 2 2 2 0 Gas vesicle protein G DUF2404 PF10296.4 KFX88249.1 - 0.0012 18.9 0.0 0.018 15.1 0.0 2.2 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Hormone_3 PF00159.13 KFX88250.1 - 0.054 13.5 0.2 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Pancreatic hormone peptide FdhD-NarQ PF02634.10 KFX88264.1 - 0.078 12.4 2.0 0.1 12.0 1.4 1.3 1 0 0 1 1 1 0 FdhD/NarQ family TFIIF_alpha PF05793.7 KFX88264.1 - 0.63 8.3 37.3 0.8 8.0 25.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PLRV_ORF5 PF01690.12 KFX88264.1 - 3.4 6.6 22.0 4.2 6.4 15.3 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Hid1 PF12722.2 KFX88264.1 - 3.6 5.1 17.9 3.8 5.0 12.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Cellulose_synt PF03552.9 KFX88264.1 - 4.6 5.4 4.8 5.8 5.0 3.3 1.2 1 0 0 1 1 1 0 Cellulose synthase SRP-alpha_N PF04086.8 KFX88264.1 - 6.1 6.1 35.9 7.9 5.7 24.9 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Silic_transp PF03842.8 KFX88264.1 - 9.7 4.1 7.5 12 3.8 5.2 1.1 1 0 0 1 1 1 0 Silicon transporter Thg1C PF14413.1 KFX88265.1 - 1.4e-50 169.9 0.2 1.9e-50 169.6 0.2 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 KFX88265.1 - 2.5e-45 153.4 0.0 3.6e-45 152.8 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase E1-E2_ATPase PF00122.15 KFX88265.1 - 0.14 11.1 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 E1-E2 ATPase Xpo1 PF08389.7 KFX88265.1 - 0.16 11.8 0.1 0.6 10.0 0.0 1.9 2 0 0 2 2 2 0 Exportin 1-like protein AlaDh_PNT_N PF05222.10 KFX88266.1 - 5.3e-28 97.7 0.0 8.5e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KFX88266.1 - 1.2e-18 67.2 0.1 1.7e-18 66.7 0.1 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Utp11 PF03998.8 KFX88268.1 - 2.2e-56 191.3 23.8 2.6e-56 191.1 16.5 1.0 1 0 0 1 1 1 1 Utp11 protein Lipoprotein_20 PF13942.1 KFX88268.1 - 4.4 6.8 10.4 10 5.6 7.2 1.6 1 1 0 1 1 1 0 YfhG lipoprotein Cmc1 PF08583.5 KFX88269.1 - 5.4e-13 48.5 5.4 1.8e-12 46.8 3.8 1.8 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like tRNA-synt_2b PF00587.20 KFX88271.1 - 1.6e-44 151.5 0.0 2.5e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFX88271.1 - 0.00059 19.7 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain ADH_zinc_N PF00107.21 KFX88272.1 - 8.9e-20 70.5 0.0 1.5e-19 69.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX88272.1 - 1.9e-05 25.5 0.0 4.8e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase HLH PF00010.21 KFX88273.1 - 7.5e-09 35.1 0.0 1.5e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Umbravirus_LDM PF04817.7 KFX88273.1 - 0.0057 15.8 0.5 0.0072 15.4 0.3 1.1 1 0 0 1 1 1 1 Umbravirus long distance movement (LDM) family A_deaminase_N PF08451.6 KFX88273.1 - 0.082 12.9 0.7 0.53 10.3 0.0 2.0 2 0 0 2 2 2 0 Adenosine/AMP deaminase N-terminal ABC_membrane PF00664.18 KFX88275.1 - 1.1e-83 280.8 24.9 3.4e-42 144.7 6.1 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFX88275.1 - 1.8e-49 167.5 0.0 9.5e-29 100.4 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFX88275.1 - 3.1e-09 36.3 4.0 0.0093 15.2 0.0 4.2 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFX88275.1 - 4.6e-06 26.7 2.2 0.011 15.7 0.4 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 KFX88275.1 - 2e-05 24.7 0.1 0.68 9.8 0.0 4.2 4 0 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.18 KFX88275.1 - 3.6e-05 23.7 0.0 0.28 11.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 KFX88275.1 - 7.6e-05 22.1 0.1 0.19 11.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KFX88275.1 - 0.00036 21.0 0.3 1.1 9.7 0.0 3.1 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 KFX88275.1 - 0.00041 19.8 1.3 1.1 8.7 0.1 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KFX88275.1 - 0.00053 19.5 0.0 0.56 9.6 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family DUF258 PF03193.11 KFX88275.1 - 0.0007 18.8 0.2 0.26 10.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KFX88275.1 - 0.0011 18.8 0.8 0.13 12.0 0.0 2.7 2 0 0 2 2 2 1 Dynamin family T2SE PF00437.15 KFX88275.1 - 0.0022 16.9 0.0 0.12 11.2 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_23 PF13476.1 KFX88275.1 - 0.0031 17.8 2.6 0.12 12.6 0.0 3.0 4 0 0 4 4 3 1 AAA domain AAA_10 PF12846.2 KFX88275.1 - 0.0037 16.7 0.1 1.7 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 KFX88275.1 - 0.018 15.8 0.2 1.9 9.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 KFX88275.1 - 0.033 13.7 0.9 9.2 5.7 0.0 3.0 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein MobB PF03205.9 KFX88275.1 - 0.098 12.3 0.3 15 5.3 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KFX88275.1 - 0.1 12.2 0.2 0.7 9.5 0.0 2.3 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 KFX88275.1 - 0.11 12.7 0.0 7.4 6.7 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.1 KFX88275.1 - 0.29 11.2 1.5 13 5.9 0.0 3.1 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.11 KFX88275.1 - 0.46 9.5 2.0 6.1 5.8 0.1 2.5 2 0 0 2 2 2 0 AIG1 family DUF87 PF01935.12 KFX88275.1 - 1.6 8.4 10.8 1.5 8.5 0.1 2.9 4 0 0 4 4 2 0 Domain of unknown function DUF87 HLH PF00010.21 KFX88276.1 - 4.5e-12 45.4 0.2 8.7e-12 44.5 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CLTH PF10607.4 KFX88277.1 - 4.9e-33 113.8 0.2 1.2e-32 112.6 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KFX88277.1 - 0.0054 16.4 0.0 0.016 14.9 0.0 1.9 1 0 0 1 1 1 1 LisH NDUF_B12 PF08122.7 KFX88278.1 - 3.6e-17 61.8 0.5 5.6e-17 61.2 0.3 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family DUF4452 PF14618.1 KFX88279.1 - 2e-54 183.8 12.4 2.4e-54 183.6 8.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) DUF4573 PF15140.1 KFX88279.1 - 0.037 13.6 4.9 0.052 13.1 3.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4573) DUF605 PF04652.11 KFX88279.1 - 10 5.4 11.2 11 5.2 7.8 1.1 1 0 0 1 1 1 0 Vta1 like Aminotran_3 PF00202.16 KFX88289.1 - 9.5e-38 129.8 0.1 3.1e-27 95.3 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-III NifW PF03206.9 KFX88289.1 - 0.14 12.2 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Nitrogen fixation protein NifW Aldedh PF00171.17 KFX88297.1 - 6.9e-188 624.6 0.4 7.7e-188 624.5 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Tim17 PF02466.14 KFX88301.1 - 3.3e-07 30.3 2.3 4.2e-07 30.0 1.1 1.6 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Pribosyltran PF00156.22 KFX88302.1 - 1.7e-13 50.3 0.1 5.2e-13 48.8 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain DUF1680 PF07944.7 KFX88303.1 - 1.2e-139 466.0 1.2 1.3e-139 465.8 0.8 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Ank_2 PF12796.2 KFX88304.1 - 3.3e-56 187.6 1.4 2.8e-17 62.8 0.0 4.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFX88304.1 - 7.9e-43 142.1 4.9 3.4e-07 29.7 0.0 9.7 8 2 1 9 9 9 9 Ankyrin repeat Ank_4 PF13637.1 KFX88304.1 - 8.6e-37 124.8 0.9 3.1e-06 27.5 0.0 6.5 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX88304.1 - 1.4e-30 102.2 2.1 0.00089 19.2 0.0 9.8 9 1 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 KFX88304.1 - 9.5e-30 101.9 2.0 9.1e-05 22.5 0.0 8.2 3 1 5 8 8 8 7 Ankyrin repeats (many copies) MFS_1 PF07690.11 KFX88306.1 - 5.1e-45 153.7 50.3 1.4e-44 152.2 33.9 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX88306.1 - 3.3e-10 39.1 32.5 4.2e-10 38.8 10.5 2.6 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 KFX88306.1 - 1.8e-09 36.5 10.9 5.5e-08 31.6 0.0 3.0 2 1 0 2 2 2 2 MFS/sugar transport protein Phage_holin_5 PF06946.6 KFX88306.1 - 1.8 8.8 7.1 0.31 11.2 0.1 3.1 3 0 0 3 3 3 0 Phage holin Sugar_tr PF00083.19 KFX88313.1 - 1.8e-118 395.9 30.5 2.1e-118 395.7 21.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX88313.1 - 5.6e-19 68.0 40.7 2.1e-13 49.7 15.8 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFX88313.1 - 6.3 6.6 13.1 5.6 6.8 1.0 4.0 4 1 0 4 4 4 0 MFS_1 like family PhyH PF05721.8 KFX88318.1 - 2.8e-12 47.1 0.0 4.7e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) YbaB_DNA_bd PF02575.11 KFX88325.1 - 0.33 10.8 3.1 0.37 10.7 0.3 2.1 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family MutS_V PF00488.16 KFX88334.1 - 1.6e-52 178.2 0.0 3e-52 177.3 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFX88334.1 - 2.7e-21 76.2 0.0 6.4e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain III zf-primase PF09329.6 KFX88335.1 - 9.8e-19 66.7 1.3 1.8e-18 65.8 0.9 1.5 1 0 0 1 1 1 1 Primase zinc finger RNase_H2-Ydr279 PF09468.5 KFX88336.1 - 1.2e-89 300.5 0.0 1.6e-89 300.1 0.0 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DUF3340 PF11818.3 KFX88336.1 - 0.043 13.7 1.4 0.077 12.9 1.0 1.3 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) PHD PF00628.24 KFX88339.1 - 1.8e-09 37.1 8.2 1.8e-09 37.1 5.7 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 KFX88339.1 - 3.4e-09 36.3 2.6 3.4e-09 36.3 1.8 4.0 3 1 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 KFX88339.1 - 1.5e-06 28.1 5.7 1.5e-06 28.1 3.9 2.8 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KFX88339.1 - 2e-06 27.3 1.4 2e-06 27.3 1.0 3.8 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX88339.1 - 5.5e-06 26.0 3.3 5.5e-06 26.0 2.3 3.7 4 1 0 4 4 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFX88339.1 - 1e-05 25.4 1.0 1e-05 25.4 0.7 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFX88339.1 - 3e-05 23.7 2.0 3e-05 23.7 1.4 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 KFX88339.1 - 0.00023 20.7 4.1 0.00023 20.7 2.8 3.6 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 KFX88339.1 - 0.00041 19.6 0.1 0.00041 19.6 0.0 2.1 2 0 0 2 2 2 1 Rtf2 RING-finger PHD_2 PF13831.1 KFX88339.1 - 0.0031 16.7 3.6 0.0031 16.7 2.5 2.1 2 0 0 2 2 2 1 PHD-finger Prok-RING_4 PF14447.1 KFX88339.1 - 0.0089 15.5 3.1 0.012 15.1 0.3 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.1 KFX88339.1 - 0.015 14.9 6.6 0.015 14.9 4.6 3.5 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.1 KFX88339.1 - 0.058 13.1 0.3 0.058 13.1 0.2 4.0 4 0 0 4 4 4 0 RING-type zinc-finger FANCL_C PF11793.3 KFX88339.1 - 0.36 10.8 9.9 0.12 12.3 1.4 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain zf-PHD-like PF15446.1 KFX88339.1 - 1.5 8.1 9.6 0.38 10.0 0.2 3.2 3 1 0 3 3 3 0 PHD/FYVE-zinc-finger like domain Prim_Zn_Ribbon PF08273.7 KFX88339.1 - 3.3 7.8 12.5 1 9.4 1.1 2.9 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase CFC PF09443.5 KFX88339.1 - 4.3 7.0 8.2 12 5.5 1.0 2.4 2 0 0 2 2 2 0 Cripto_Frl-1_Cryptic (CFC) DZR PF12773.2 KFX88339.1 - 4.7 7.1 10.4 4.2e+02 0.8 7.2 2.7 1 1 0 1 1 1 0 Double zinc ribbon Ribosomal_L37ae PF01780.14 KFX88340.1 - 1e-39 134.2 8.8 1.1e-39 134.1 6.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 KFX88340.1 - 0.00043 20.0 2.7 0.00066 19.4 1.9 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 KFX88340.1 - 0.0063 15.9 3.4 0.025 14.0 0.1 2.1 2 0 0 2 2 2 1 A2L zinc ribbon domain Sgf11 PF08209.6 KFX88340.1 - 0.044 13.1 0.3 0.43 9.9 0.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Thymidylat_synt PF00303.14 KFX88340.1 - 0.048 12.6 0.0 0.058 12.3 0.0 1.1 1 0 0 1 1 1 0 Thymidylate synthase zf-BED PF02892.10 KFX88340.1 - 0.067 12.9 4.7 1.5 8.6 0.2 2.3 1 1 1 2 2 2 0 BED zinc finger OrfB_Zn_ribbon PF07282.6 KFX88340.1 - 0.12 12.0 1.2 0.17 11.5 0.8 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF1451 PF07295.6 KFX88340.1 - 0.16 11.7 0.6 0.22 11.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) CarbpepA_inh PF02977.10 KFX88340.1 - 0.21 11.1 0.3 0.21 11.1 0.2 2.1 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor Zn-ribbon_8 PF09723.5 KFX88340.1 - 0.4 10.6 4.0 0.6 10.1 0.1 2.2 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2 PF00096.21 KFX88340.1 - 0.48 10.8 4.6 0.74 10.2 0.4 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFX88340.1 - 1.6 9.1 7.5 0.68 10.3 0.5 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Saccharop_dh PF03435.13 KFX88341.1 - 7.4e-17 61.3 0.0 1e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KFX88341.1 - 0.022 14.8 0.0 0.055 13.5 0.0 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase BcrAD_BadFG PF01869.15 KFX88341.1 - 0.047 12.9 0.0 0.079 12.2 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DUF423 PF04241.10 KFX88345.1 - 0.0068 16.3 0.9 0.0068 16.3 0.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF423) VSP PF03302.8 KFX88353.1 - 0.14 10.7 0.8 0.22 10.0 0.5 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein T2SE PF00437.15 KFX88374.1 - 0.0011 17.9 0.1 0.0021 17.0 0.0 1.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_17 PF13207.1 KFX88374.1 - 0.0012 19.6 0.0 0.0012 19.6 0.0 3.1 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 KFX88374.1 - 0.0085 16.3 8.2 0.062 13.6 0.0 4.1 4 0 0 4 4 4 1 AAA domain PRK PF00485.13 KFX88374.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 KFX88374.1 - 0.066 12.2 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin MobB PF03205.9 KFX88374.1 - 0.13 12.0 0.1 0.31 10.7 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KFX88374.1 - 0.14 12.4 0.1 0.95 9.7 0.1 2.2 2 0 0 2 2 2 0 ABC transporter DUF904 PF06005.7 KFX88375.1 - 0.054 13.7 0.1 0.054 13.7 0.1 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Dak1 PF02733.12 KFX88375.1 - 0.067 11.7 0.1 0.17 10.4 0.1 1.6 1 0 0 1 1 1 0 Dak1 domain DUF1843 PF08898.5 KFX88375.1 - 0.86 9.6 4.7 2.1 8.4 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) FtsL PF04999.8 KFX88375.1 - 1.2 8.9 11.3 1 9.1 0.1 3.6 3 1 1 4 4 4 0 Cell division protein FtsL HALZ PF02183.13 KFX88375.1 - 2.8 7.7 11.3 16 5.2 2.3 3.7 2 1 1 3 3 3 0 Homeobox associated leucine zipper Rrp15p PF07890.7 KFX88378.1 - 6.6e-36 123.2 11.8 6.6e-36 123.2 8.2 1.9 2 0 0 2 2 2 1 Rrp15p Daxx PF03344.10 KFX88378.1 - 1 7.7 21.6 1.3 7.4 15.0 1.1 1 0 0 1 1 1 0 Daxx Family Peptidase_S64 PF08192.6 KFX88378.1 - 7 4.8 13.4 8.3 4.6 9.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 SRP54 PF00448.17 KFX88379.1 - 2.2e-76 255.6 1.9 2.8e-76 255.3 0.9 1.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KFX88379.1 - 7.1e-25 87.2 4.4 7.1e-25 87.2 3.0 4.3 4 2 2 6 6 4 1 Signal peptide binding domain SRP54_N PF02881.14 KFX88379.1 - 2.1e-16 59.7 1.3 4.8e-16 58.6 0.9 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 KFX88379.1 - 1.5e-08 34.2 0.1 4.9e-08 32.6 0.1 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KFX88379.1 - 5.1e-07 29.6 0.0 1.1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFX88379.1 - 1e-05 26.3 0.0 2.8e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 KFX88379.1 - 1.5e-05 24.7 0.1 5.8e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 KFX88379.1 - 2.6e-05 23.4 0.0 2.6e-05 23.4 0.0 1.9 2 0 0 2 2 1 1 Zeta toxin AAA_31 PF13614.1 KFX88379.1 - 0.00017 21.5 0.0 0.15 11.9 0.0 2.4 1 1 0 2 2 2 2 AAA domain APS_kinase PF01583.15 KFX88379.1 - 0.00089 18.9 0.0 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.1 KFX88379.1 - 0.0011 19.0 0.0 0.0027 17.7 0.0 1.7 1 1 1 2 2 2 1 AAA ATPase domain CbiA PF01656.18 KFX88379.1 - 0.0018 17.6 0.2 0.0071 15.7 0.2 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.1 KFX88379.1 - 0.0019 18.3 0.0 0.0059 16.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.5 KFX88379.1 - 0.0033 16.6 1.4 1.8 7.7 1.2 3.1 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Thymidylate_kin PF02223.12 KFX88379.1 - 0.0039 16.5 0.0 0.014 14.7 0.0 2.0 1 0 0 1 1 1 1 Thymidylate kinase ATP_bind_1 PF03029.12 KFX88379.1 - 0.0053 16.3 0.6 0.03 13.8 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 KFX88379.1 - 0.0082 16.4 0.0 0.022 15.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KFX88379.1 - 0.02 15.1 0.2 0.054 13.7 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) 6PF2K PF01591.13 KFX88379.1 - 0.028 13.5 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_28 PF13521.1 KFX88379.1 - 0.031 14.2 0.2 0.065 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain Torsin PF06309.6 KFX88379.1 - 0.031 14.1 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 Torsin TrwB_AAD_bind PF10412.4 KFX88379.1 - 0.035 12.7 0.0 0.074 11.6 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Cmc1 PF08583.5 KFX88381.1 - 0.0079 15.9 1.1 0.018 14.7 0.7 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Mt_ATP-synt_B PF05405.9 KFX88381.1 - 0.044 13.2 1.5 1.6 8.1 0.1 3.0 2 1 1 3 3 3 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2562 PF10814.3 KFX88381.1 - 0.044 13.7 0.2 0.098 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) Lip_prot_lig_C PF10437.4 KFX88381.1 - 0.093 12.4 0.2 0.45 10.2 0.0 2.3 2 1 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus Tom22 PF04281.8 KFX88381.1 - 0.2 11.2 1.6 1.2 8.7 0.2 2.2 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Aldose_epim PF01263.15 KFX88382.1 - 1.6e-33 116.1 0.0 2e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Terminase_5 PF06056.7 KFX88382.1 - 0.15 11.6 0.2 14 5.3 0.1 2.7 3 0 0 3 3 3 0 Putative ATPase subunit of terminase (gpP-like) DUF2427 PF10348.4 KFX88385.1 - 1.8e-06 27.4 2.0 3.7e-06 26.4 1.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) DOMON PF03351.12 KFX88385.1 - 2.5e-05 24.2 0.1 4.3e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.11 KFX88385.1 - 6.9e-05 22.6 9.6 6.9e-05 22.6 6.7 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Herpes_gE PF02480.11 KFX88391.1 - 0.043 12.0 0.0 0.054 11.7 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SET PF00856.23 KFX88396.1 - 3.7e-09 37.0 0.2 1.3e-08 35.2 0.0 2.0 2 0 0 2 2 2 1 SET domain Trypan_PARP PF05887.6 KFX88396.1 - 0.16 11.7 16.4 0.28 11.0 11.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ATP_bind_1 PF03029.12 KFX88398.1 - 1.1e-69 234.6 0.0 1.3e-69 234.3 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KFX88398.1 - 4.3e-05 24.3 0.0 0.00011 23.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFX88398.1 - 0.00039 20.3 0.0 0.00064 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KFX88398.1 - 0.0028 17.2 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KFX88398.1 - 0.0031 17.2 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KFX88398.1 - 0.0037 17.4 0.0 0.0067 16.5 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 KFX88398.1 - 0.0045 17.1 0.0 0.0084 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFX88398.1 - 0.0089 16.0 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 KFX88398.1 - 0.01 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KFX88398.1 - 0.014 14.8 0.0 0.48 9.8 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 KFX88398.1 - 0.015 15.0 0.0 0.046 13.4 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 KFX88398.1 - 0.017 14.8 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 KFX88398.1 - 0.018 15.2 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KFX88398.1 - 0.025 14.1 0.0 0.22 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 KFX88398.1 - 0.026 13.9 0.0 2.3 7.6 0.0 2.5 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain UPF0079 PF02367.12 KFX88398.1 - 0.028 14.0 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SRP54 PF00448.17 KFX88398.1 - 0.033 13.6 0.0 0.055 12.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SE PF00437.15 KFX88398.1 - 0.037 12.9 0.0 0.055 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.1 KFX88398.1 - 0.046 14.0 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KFX88398.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 KFX88398.1 - 0.064 12.2 0.0 0.099 11.6 0.0 1.2 1 0 0 1 1 1 0 Septin KAP_NTPase PF07693.9 KFX88398.1 - 0.065 12.2 0.0 0.065 12.2 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain ArsA_ATPase PF02374.10 KFX88398.1 - 0.078 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Anion-transporting ATPase FtsK_SpoIIIE PF01580.13 KFX88398.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.1 KFX88398.1 - 0.11 11.8 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KFX88398.1 - 0.13 11.9 0.0 0.88 9.2 0.0 2.0 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 KFX88398.1 - 0.14 11.6 0.0 0.54 9.7 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 KFX88398.1 - 0.14 11.8 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Gtr1_RagA PF04670.7 KFX88398.1 - 0.15 11.1 0.1 0.42 9.7 0.0 1.9 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region IstB_IS21 PF01695.12 KFX88398.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein S-AdoMet_synt_C PF02773.11 KFX88399.1 - 3e-76 253.7 0.1 5.3e-76 252.9 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 KFX88399.1 - 1.2e-47 160.8 0.0 2e-47 160.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KFX88399.1 - 3e-42 142.9 0.4 7.6e-42 141.5 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain DEAD PF00270.24 KFX88424.1 - 1.7e-45 154.5 0.0 1.5e-44 151.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX88424.1 - 6.4e-24 83.6 0.0 2e-23 82.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX88424.1 - 0.00068 19.5 0.0 0.024 14.4 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KFX88424.1 - 0.0015 17.3 0.0 0.0023 16.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Aa_trans PF01490.13 KFX88425.1 - 4.2e-29 101.2 37.2 5.4e-29 100.8 25.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Shisa PF13908.1 KFX88425.1 - 2 8.5 4.8 17 5.4 0.3 2.9 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator SNF2_N PF00176.18 KFX88434.1 - 1.5e-73 247.2 0.6 3.1e-73 246.1 0.4 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFX88434.1 - 8.5e-15 54.3 0.1 2.8e-14 52.7 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFX88434.1 - 7.4e-05 22.3 0.0 0.0002 20.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase HSA PF07529.8 KFX88434.1 - 0.00011 21.8 7.6 0.00011 21.8 5.3 3.3 2 1 1 3 3 3 1 HSA DEAD_2 PF06733.10 KFX88434.1 - 0.025 13.9 0.0 0.074 12.4 0.0 1.7 1 0 0 1 1 1 0 DEAD_2 zf-CCCH PF00642.19 KFX88436.1 - 3.7e-09 36.0 9.5 0.00018 21.0 1.8 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Frag1 PF10277.4 KFX88443.1 - 1.3e-43 148.9 9.9 2e-43 148.3 6.8 1.3 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family U3_assoc_6 PF08640.6 KFX88444.1 - 5.5e-25 86.9 0.0 3.9e-24 84.2 0.0 2.0 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TRI12 PF06609.8 KFX88447.1 - 3.2e-41 141.2 29.8 3.8e-41 140.9 20.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KFX88447.1 - 1.3e-21 76.6 58.2 1.3e-21 76.6 40.3 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX88447.1 - 6.4e-11 41.4 36.7 8.6e-10 37.7 7.9 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter IMD PF08397.6 KFX88448.1 - 0.0093 15.3 0.5 0.011 15.0 0.3 1.2 1 0 0 1 1 1 1 IRSp53/MIM homology domain Seryl_tRNA_N PF02403.17 KFX88448.1 - 0.093 12.7 0.4 0.17 11.9 0.2 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Ribonuc_red_sm PF00268.16 KFX88460.1 - 4.4e-113 376.9 3.6 5.2e-113 376.7 2.5 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.7 KFX88461.1 - 2.5e-26 91.1 0.2 3.1e-26 90.9 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) DUF1308 PF07000.6 KFX88462.1 - 2.6e-72 243.4 0.0 4.2e-72 242.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) Aminotran_1_2 PF00155.16 KFX88469.1 - 1.8e-16 60.0 0.0 2.4e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KFX88469.1 - 0.0031 16.1 0.0 0.0096 14.5 0.0 1.8 2 1 0 2 2 2 1 Alanine-glyoxylate amino-transferase UCR_14kD PF02271.11 KFX88472.1 - 1.3e-45 153.4 0.0 1.5e-45 153.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit G-alpha PF00503.15 KFX88490.1 - 5.5e-92 308.4 6.2 6.1e-92 308.2 4.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFX88490.1 - 1.4e-11 43.9 0.3 3.2e-11 42.7 0.2 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family zf-CHC2 PF01807.15 KFX88490.1 - 1.7e-05 24.2 0.1 9.7e-05 21.8 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger adh_short PF00106.20 KFX88502.1 - 5.2e-24 85.0 4.4 6.4e-24 84.7 3.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX88502.1 - 1.4e-20 74.0 0.1 1.7e-20 73.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX88502.1 - 1.3e-12 47.7 1.6 1.8e-12 47.3 1.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_2 PF03446.10 KFX88502.1 - 0.0079 16.0 0.4 0.14 11.9 0.2 2.1 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3Beta_HSD PF01073.14 KFX88502.1 - 0.02 13.6 0.0 0.032 12.9 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PhoD PF09423.5 KFX88504.1 - 3e-06 26.0 0.0 7.4e-06 24.7 0.0 1.5 1 1 0 1 1 1 1 PhoD-like phosphatase SMC_N PF02463.14 KFX88506.1 - 1.5e-31 109.3 23.0 4.3e-31 107.8 15.9 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KFX88506.1 - 1.1e-27 96.4 0.0 3.1e-27 94.9 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 KFX88506.1 - 4e-13 50.1 24.4 4e-13 50.1 16.9 4.8 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 KFX88506.1 - 6.1e-07 29.6 0.6 2.3e-06 27.8 0.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFX88506.1 - 0.00064 19.2 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF4304 PF14137.1 KFX88506.1 - 0.077 13.1 0.7 4.2 7.5 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4304) Reo_sigmaC PF04582.7 KFX88506.1 - 0.089 11.9 14.4 0.3 10.2 0.1 4.3 2 2 3 5 5 5 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 KFX88506.1 - 0.1 11.0 0.0 0.1 11.0 0.0 4.7 3 2 1 4 4 4 0 AAA domain ABC_tran PF00005.22 KFX88506.1 - 0.35 11.1 0.0 0.35 11.1 0.0 4.3 3 3 1 4 4 4 0 ABC transporter APG6 PF04111.7 KFX88506.1 - 0.49 9.3 78.0 0.039 12.9 5.2 5.2 2 2 3 5 5 5 0 Autophagy protein Apg6 RIO1 PF01163.17 KFX88507.1 - 2e-67 226.2 1.2 2e-67 226.2 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 KFX88507.1 - 0.00018 20.6 0.2 0.0015 17.5 0.1 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFX88507.1 - 0.00098 18.9 1.7 0.66 9.6 0.1 2.7 2 1 0 3 3 3 2 Phosphotransferase enzyme family Prismane PF03063.15 KFX88507.1 - 0.054 11.8 0.0 0.091 11.1 0.0 1.3 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family SNARE PF05739.14 KFX88508.1 - 3.3e-19 68.3 1.9 3.3e-19 68.3 1.3 2.1 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 KFX88508.1 - 2.7e-13 49.9 0.4 2.7e-13 49.9 0.3 2.4 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 KFX88508.1 - 0.0021 17.6 6.5 0.0059 16.1 0.6 2.5 3 0 0 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain DNA_repr_REX1B PF14966.1 KFX88508.1 - 0.25 11.7 0.1 0.25 11.7 0.0 2.7 3 1 0 3 3 3 0 DNA repair REX1-B EF-hand_1 PF00036.27 KFX88509.1 - 1.2e-40 133.7 12.8 1.6e-09 36.3 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFX88509.1 - 2e-36 123.9 6.4 3.8e-20 71.7 0.8 2.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 KFX88509.1 - 4.3e-34 115.8 12.8 9.6e-16 57.1 0.4 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KFX88509.1 - 6.3e-30 100.3 8.4 1.8e-09 36.7 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFX88509.1 - 2.1e-25 86.8 9.7 2e-06 26.8 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KFX88509.1 - 1.3e-15 57.0 0.2 3.6e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 KFX88509.1 - 5e-09 36.1 0.3 0.0021 18.0 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFX88509.1 - 2.7e-08 33.4 2.9 0.0028 17.3 0.2 2.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 KFX88509.1 - 8.1e-08 31.7 0.1 0.033 13.8 0.0 3.3 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 KFX88509.1 - 2.8e-06 27.2 2.2 1.6e-05 24.7 0.2 2.4 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 KFX88509.1 - 0.0002 21.1 0.4 0.44 10.2 0.0 2.4 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 KFX88509.1 - 0.00081 18.9 0.2 0.098 12.2 0.1 2.8 1 1 0 1 1 1 1 Caleosin related protein Tenui_NCP PF04876.7 KFX88509.1 - 0.0045 16.5 0.1 0.23 11.0 0.0 2.4 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 KFX88509.1 - 0.0045 16.9 1.1 1.4 8.9 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb4 Toprim_2 PF13155.1 KFX88509.1 - 0.0053 17.0 2.4 0.55 10.5 0.1 2.5 1 1 1 2 2 2 1 Toprim-like DUF1104 PF06518.6 KFX88509.1 - 0.02 14.9 4.3 2.4 8.3 1.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) DUF3349 PF11829.3 KFX88509.1 - 0.054 13.9 0.3 20 5.6 0.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 KFX88509.1 - 0.24 11.0 2.1 1.1 9.0 0.1 2.9 2 2 2 4 4 4 0 EF hand RloB PF13707.1 KFX88509.1 - 0.41 10.2 6.0 23 4.6 4.0 2.3 1 1 0 1 1 1 0 RloB-like protein PB1 PF00564.19 KFX88509.1 - 0.43 10.2 1.9 38 4.0 0.1 3.2 2 1 1 3 3 3 0 PB1 domain Glyco_hydro_47 PF01532.15 KFX88510.1 - 1.4e-170 567.8 0.0 1.6e-170 567.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MSP1a PF11670.3 KFX88511.1 - 0.076 12.8 1.0 0.14 11.9 0.1 1.7 1 1 1 2 2 2 0 Major surface protein 1a (MSP1a) APH PF01636.18 KFX88514.1 - 0.00072 19.3 0.0 0.00093 18.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX88514.1 - 0.041 13.4 0.7 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase CIAPIN1 PF05093.8 KFX88515.1 - 6.5e-34 116.0 2.1 1e-33 115.4 1.5 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis zf-CSL PF05207.8 KFX88515.1 - 0.5 9.9 2.8 1.6 8.2 1.9 1.8 1 1 0 1 1 1 0 CSL zinc finger NAD_binding_6 PF08030.7 KFX88518.1 - 1.8e-21 76.6 0.1 1.6e-19 70.3 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KFX88518.1 - 1.3e-19 70.5 7.7 1.3e-19 70.5 5.3 2.6 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KFX88518.1 - 1.3e-11 44.2 0.0 7.5e-11 41.8 0.0 2.2 2 1 0 2 2 2 1 FAD-binding domain Med5 PF08689.5 KFX88528.1 - 9.1e-09 33.6 0.0 1.1e-08 33.3 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 DAO PF01266.19 KFX88531.1 - 3.2e-47 161.1 0.0 3.9e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFX88531.1 - 0.00025 21.1 0.0 0.013 15.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX88531.1 - 0.013 15.3 0.1 0.74 9.5 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KFX88531.1 - 0.017 15.1 0.0 0.037 14.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF2370 PF10176.4 KFX88532.1 - 0.054 12.8 0.2 0.075 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Vfa1 PF08432.5 KFX88532.1 - 0.12 12.4 6.4 0.21 11.6 4.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Bud13 PF09736.4 KFX88532.1 - 0.18 12.0 5.0 0.33 11.2 3.4 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Prefoldin PF02996.12 KFX88532.1 - 0.36 10.4 5.7 2.3 7.8 0.1 2.7 2 1 0 2 2 2 0 Prefoldin subunit DUF92 PF01940.11 KFX88533.1 - 4.3e-65 219.0 4.1 5.9e-65 218.5 2.9 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 FAD_binding_3 PF01494.14 KFX88533.1 - 3.3e-36 125.0 0.8 4.6e-36 124.6 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KFX88533.1 - 1.2e-05 25.5 0.0 3.6e-05 23.9 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFX88533.1 - 0.00013 20.9 0.5 0.066 12.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 KFX88533.1 - 0.0006 18.9 0.0 0.0012 18.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KFX88533.1 - 0.0012 19.2 0.7 3.6 8.0 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFX88533.1 - 0.094 11.6 0.4 0.61 8.9 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein FAA_hydrolase PF01557.13 KFX88534.1 - 9.6e-49 165.7 0.0 1.7e-48 164.9 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans PF04082.13 KFX88534.1 - 5.8e-15 54.8 2.1 9.1e-15 54.2 0.3 2.2 4 0 0 4 4 4 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX88534.1 - 0.0015 18.4 18.1 0.0016 18.2 10.7 2.4 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0565 PF10561.4 KFX88534.1 - 0.038 12.8 0.0 0.1 11.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 Glyoxalase PF00903.20 KFX88535.1 - 1.5e-10 41.1 3.2 2.7e-09 37.0 0.9 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KFX88535.1 - 0.00026 21.5 0.2 0.02 15.5 0.1 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain FAD_binding_3 PF01494.14 KFX88536.1 - 1.1e-32 113.4 0.0 2.2e-17 63.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 KFX88536.1 - 0.00035 19.7 0.1 0.00055 19.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 KFX88536.1 - 0.00096 19.1 0.1 0.0023 17.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFX88536.1 - 0.072 11.9 0.1 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KFX88536.1 - 0.26 10.1 0.4 5.7 5.7 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 KFX88537.1 - 6.4e-48 163.5 0.2 8.3e-48 163.2 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFX88537.1 - 1.5e-07 30.6 0.1 4e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFX88537.1 - 2.7e-06 27.7 0.0 0.0012 19.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX88537.1 - 5.1e-06 26.4 0.0 1.5e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KFX88537.1 - 1.7e-05 23.4 0.1 0.0021 16.5 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KFX88537.1 - 4.1e-05 22.7 0.0 7.8e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 KFX88537.1 - 0.00055 20.0 0.3 0.0018 18.3 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFX88537.1 - 0.0009 18.1 0.5 0.0036 16.1 0.4 2.0 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 KFX88537.1 - 0.0015 17.2 0.4 0.2 10.2 0.1 2.3 1 1 1 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 KFX88537.1 - 0.0016 18.3 0.1 0.0026 17.6 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 KFX88537.1 - 0.005 16.2 0.0 0.26 10.6 0.0 2.7 3 0 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_oxidored PF12831.2 KFX88537.1 - 0.0073 15.4 1.5 0.03 13.4 1.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KFX88537.1 - 0.0092 15.6 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KFX88537.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 KFX88537.1 - 0.013 14.3 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 KFX88537.1 - 0.017 14.8 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 KFX88537.1 - 0.027 13.9 0.1 0.048 13.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.1 KFX88537.1 - 0.028 14.7 0.1 0.053 13.8 0.1 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.14 KFX88537.1 - 0.046 12.8 0.0 0.079 12.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KFX88537.1 - 0.051 13.8 0.0 0.13 12.5 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 KFX88537.1 - 0.066 12.1 0.0 0.094 11.6 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Cellulase PF00150.13 KFX88558.1 - 2.7e-11 43.1 0.7 8e-11 41.6 0.0 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF4246 PF14033.1 KFX88559.1 - 2.1e-148 495.0 0.0 2.5e-148 494.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) COesterase PF00135.23 KFX88560.1 - 1.6e-93 314.2 0.2 1.9e-93 313.9 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX88560.1 - 0.0041 16.7 0.1 0.0092 15.5 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX88560.1 - 0.038 13.7 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Zn_clus PF00172.13 KFX88561.1 - 1.1e-07 31.6 12.2 2e-07 30.7 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX88562.1 - 2e-24 85.9 0.3 3.7e-24 85.0 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KFX88563.1 - 2.9e-31 108.4 22.2 4e-31 108.0 15.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DHDPS PF00701.17 KFX88564.1 - 6.3e-35 120.1 0.0 7.4e-35 119.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Mito_carr PF00153.22 KFX88565.1 - 1.3e-46 156.1 6.8 5.3e-18 64.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HA2 PF04408.18 KFX88567.1 - 1.1e-15 57.4 0.1 2.1e-15 56.5 0.1 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KFX88567.1 - 1.3e-14 53.9 0.0 3.2e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KFX88567.1 - 1e-11 44.5 0.0 2.7e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFX88567.1 - 0.047 13.1 0.0 0.85 9.0 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase zf-C2H2 PF00096.21 KFX88574.1 - 6.6e-05 23.0 7.0 0.0063 16.7 0.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX88574.1 - 0.00056 20.0 9.6 0.0046 17.1 0.5 3.0 2 1 1 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFX88574.1 - 0.031 14.5 3.0 0.031 14.5 2.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain Atx10homo_assoc PF09759.4 KFX88576.1 - 1e-14 54.0 0.0 3e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain KH_1 PF00013.24 KFX88576.1 - 5.8e-13 48.2 1.1 4.5e-12 45.4 0.1 2.5 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 KFX88576.1 - 4e-10 39.0 0.6 9.1e-10 37.9 0.4 1.7 1 0 0 1 1 1 1 KH domain DUF2521 PF10730.4 KFX88576.1 - 0.03 14.1 0.3 6.8 6.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2521) DUF2408 PF10303.4 KFX88576.1 - 0.031 14.4 0.6 0.098 12.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Glyoxalase PF00903.20 KFX88577.1 - 5e-35 120.2 0.0 2e-16 60.0 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KFX88577.1 - 8e-30 103.6 0.0 2e-13 50.9 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KFX88577.1 - 1.4e-14 54.0 0.0 5.7e-06 26.2 0.0 3.3 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KFX88577.1 - 4.5e-06 26.6 0.0 0.046 13.6 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain GFA PF04828.9 KFX88579.1 - 5.7e-25 87.0 0.1 8e-25 86.6 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Acetyltransf_2 PF00797.12 KFX88580.1 - 8.5e-42 143.3 0.0 1.2e-41 142.8 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase Sporozoite_P67 PF05642.6 KFX88582.1 - 0.79 7.5 5.4 0.85 7.4 3.8 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NACHT PF05729.7 KFX88583.1 - 2.7e-11 43.4 0.0 6.9e-11 42.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.1 KFX88583.1 - 1.4e-06 27.8 0.0 3.3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFX88583.1 - 0.00098 19.2 0.0 0.0061 16.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFX88583.1 - 0.0054 16.7 0.0 0.055 13.4 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.9 KFX88583.1 - 0.0075 15.3 0.1 0.065 12.2 0.0 2.0 1 1 1 2 2 2 1 KAP family P-loop domain RNA_helicase PF00910.17 KFX88583.1 - 0.03 14.5 0.0 1.4 9.1 0.0 3.0 3 0 0 3 3 3 0 RNA helicase AAA_33 PF13671.1 KFX88583.1 - 0.056 13.3 0.1 8.1 6.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain CorA PF01544.13 KFX88584.1 - 2.1e-05 23.7 0.1 4.2e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein VKOR PF07884.9 KFX88584.1 - 0.012 15.4 1.5 0.035 13.9 1.0 1.6 1 1 0 1 1 1 0 Vitamin K epoxide reductase family CTP_transf_2 PF01467.21 KFX88590.1 - 2.3e-12 47.2 0.0 5.8e-12 45.9 0.0 1.7 1 1 0 1 1 1 1 Cytidylyltransferase Cutinase PF01083.17 KFX88590.1 - 0.00011 21.9 0.0 0.00041 20.1 0.0 1.9 2 0 0 2 2 2 1 Cutinase PGAP1 PF07819.8 KFX88590.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein TPR_12 PF13424.1 KFX88591.1 - 3.2e-57 190.4 34.5 6.4e-15 54.8 0.0 6.2 5 2 3 8 8 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 KFX88591.1 - 3.3e-48 160.3 25.8 2.4e-06 27.2 0.0 8.6 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_11 PF13414.1 KFX88591.1 - 2.1e-23 81.7 19.5 1.1e-07 31.3 0.0 5.9 3 1 2 6 6 5 5 TPR repeat TPR_16 PF13432.1 KFX88591.1 - 1.7e-21 76.3 26.7 1e-05 26.0 0.3 6.4 6 1 1 7 7 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 KFX88591.1 - 2.3e-20 70.7 21.7 0.0048 16.5 0.0 8.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.23 KFX88591.1 - 4.1e-18 64.1 37.4 0.0013 18.2 1.0 9.4 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 KFX88591.1 - 7.8e-18 62.9 31.9 0.001 18.7 1.5 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat Apc3 PF12895.2 KFX88591.1 - 2.7e-14 53.0 13.7 0.00025 21.1 0.6 5.3 2 2 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KFX88591.1 - 4.9e-12 46.0 18.4 0.002 18.3 0.0 6.5 2 2 3 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.1 KFX88591.1 - 3.5e-11 42.3 16.2 0.013 15.6 0.0 9.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFX88591.1 - 4.1e-09 36.2 22.4 0.91 10.3 0.1 8.8 3 2 5 8 8 8 3 Tetratricopeptide repeat TPR_4 PF07721.9 KFX88591.1 - 2.2e-08 33.7 6.8 3 8.5 0.1 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 KFX88591.1 - 2.6e-08 33.1 0.0 4.9e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Phosphorylase superfamily NB-ARC PF00931.17 KFX88591.1 - 2.5e-07 29.8 0.0 8.1e-07 28.1 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.1 KFX88591.1 - 2.6e-05 24.3 0.0 0.00015 21.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KFX88591.1 - 0.00054 19.7 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase TPR_8 PF13181.1 KFX88591.1 - 0.00091 18.8 22.5 0.088 12.6 0.6 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFX88591.1 - 0.0021 18.3 22.5 0.081 13.4 0.0 7.8 9 0 0 9 9 7 2 Tetratricopeptide repeat IstB_IS21 PF01695.12 KFX88591.1 - 0.015 14.6 0.0 0.042 13.2 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein TPR_3 PF07720.7 KFX88591.1 - 0.016 15.0 23.5 2.4 8.0 0.4 6.6 7 0 0 7 7 7 0 Tetratricopeptide repeat SRP54 PF00448.17 KFX88591.1 - 0.026 13.9 0.0 0.071 12.5 0.0 1.7 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain TPR_20 PF14561.1 KFX88591.1 - 0.032 14.3 4.3 3 8.0 0.0 4.7 2 1 2 5 5 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 KFX88591.1 - 0.04 13.1 8.0 7.6 5.8 0.1 4.6 4 0 0 4 4 4 0 SHNi-TPR DNA_pol3_delta2 PF13177.1 KFX88591.1 - 0.082 12.5 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 0 DNA polymerase III, delta subunit DUF1925 PF09094.6 KFX88591.1 - 0.12 12.3 0.4 7.5 6.6 0.0 3.8 4 1 0 4 4 3 0 Domain of unknown function (DUF1925) BTAD PF03704.12 KFX88591.1 - 0.28 11.4 16.2 6.7 7.0 0.0 4.7 3 2 2 5 5 4 0 Bacterial transcriptional activator domain Pyrophosphatase PF00719.14 KFX88594.1 - 3.9e-52 175.8 0.1 4.9e-52 175.5 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase SUI1 PF01253.17 KFX88600.1 - 1.4e-28 98.4 6.3 1.4e-28 98.4 4.4 1.4 2 0 0 2 2 2 1 Translation initiation factor SUI1 HERV-K_env_2 PF13804.1 KFX88601.1 - 0.14 11.7 0.1 0.17 11.3 0.1 1.1 1 0 0 1 1 1 0 Retro-transcribing viruses envelope glycoprotein PUF PF00806.14 KFX88624.1 - 4.7e-57 186.3 11.7 6.6e-08 31.6 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CCDC-167 PF15188.1 KFX88624.1 - 0.7 9.8 6.8 1.9 8.5 4.7 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Zn_clus PF00172.13 KFX88626.1 - 3.1e-10 39.8 8.5 6.9e-10 38.6 5.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N_2 PF13602.1 KFX88627.1 - 1.8e-17 64.4 0.0 4.1e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KFX88627.1 - 4.8e-13 48.8 0.0 9.7e-13 47.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX88627.1 - 6.1e-07 29.1 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.19 KFX88627.1 - 1.9e-05 24.9 0.1 3.4e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KFX88627.1 - 2e-05 24.6 0.5 4.2e-05 23.6 0.3 1.5 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 KFX88627.1 - 6.7e-05 22.7 1.3 0.00011 22.1 0.2 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 KFX88627.1 - 0.0091 14.9 0.0 0.021 13.7 0.0 1.6 1 0 0 1 1 1 1 RmlD substrate binding domain THF_DHG_CYH_C PF02882.14 KFX88627.1 - 0.045 12.8 0.5 0.18 10.8 0.4 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short PF00106.20 KFX88627.1 - 0.05 13.5 0.3 0.59 10.0 0.1 2.2 2 0 0 2 2 2 0 short chain dehydrogenase NmrA PF05368.8 KFX88627.1 - 0.11 11.7 1.2 0.13 11.4 0.1 1.6 2 0 0 2 2 2 0 NmrA-like family Pyr_redox_2 PF07992.9 KFX88628.1 - 1.2e-16 61.2 0.0 5.4e-16 59.0 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX88628.1 - 6.6e-12 45.6 4.8 1.3e-09 38.2 0.3 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFX88628.1 - 3.2e-06 26.2 7.8 0.083 11.7 0.1 4.1 4 0 0 4 4 4 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFX88628.1 - 5.4e-06 26.6 0.4 0.0013 18.8 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX88628.1 - 0.0033 17.4 0.2 1.4 8.9 0.2 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KFX88628.1 - 0.014 15.1 1.4 12 5.6 0.0 3.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KFX88628.1 - 0.04 12.7 2.4 0.14 10.9 0.2 2.3 2 0 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.1 KFX88628.1 - 0.11 11.3 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 KFX88628.1 - 0.37 9.6 4.4 3.9 6.2 0.1 3.5 4 0 0 4 4 4 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 KFX88628.1 - 6.4 5.2 5.9 6.3 5.3 0.4 2.7 3 0 0 3 3 3 0 Tryptophan halogenase DUF4102 PF13356.1 KFX88633.1 - 0.13 12.1 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4102) CBM-like PF14683.1 KFX88658.1 - 3.6e-14 52.7 0.1 6e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 KFX88658.1 - 2.5e-10 40.3 0.3 7.1e-10 38.8 0.2 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 KFX88658.1 - 0.075 13.1 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Choline_kinase PF01633.15 KFX88660.1 - 7.1e-61 205.4 0.0 3.1e-60 203.3 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 KFX88660.1 - 4.6e-22 77.2 0.0 1e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 KFX88660.1 - 7.9e-08 32.3 1.3 9.8e-08 32.0 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Aldo_ket_red PF00248.16 KFX88662.1 - 2.7e-19 69.0 0.0 3.1e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HLH PF00010.21 KFX88664.1 - 1.8e-12 46.7 1.8 6.8e-12 44.8 1.2 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DivIC PF04977.10 KFX88664.1 - 0.14 11.6 1.0 0.46 10.0 0.7 1.8 1 0 0 1 1 1 0 Septum formation initiator Ly49 PF08391.5 KFX88664.1 - 0.2 11.8 2.9 0.28 11.2 1.6 1.6 1 1 0 1 1 1 0 Ly49-like protein, N-terminal region APG6 PF04111.7 KFX88664.1 - 0.27 10.2 5.9 0.42 9.6 4.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Lysyl_oxidase PF01186.12 KFX88664.1 - 0.32 10.5 0.1 0.32 10.5 0.0 1.5 2 0 0 2 2 2 0 Lysyl oxidase HAUS-augmin3 PF14932.1 KFX88664.1 - 2.1 7.4 8.8 1.6 7.8 4.8 1.8 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 IncA PF04156.9 KFX88664.1 - 2.4 7.7 4.8 4.6 6.7 3.3 1.4 1 0 0 1 1 1 0 IncA protein DUF4239 PF14023.1 KFX88664.1 - 2.6 7.3 4.7 2.6 7.3 2.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) Tcp11 PF05794.8 KFX88667.1 - 3.4e-65 220.4 0.2 1e-64 218.8 0.0 1.8 2 0 0 2 2 2 1 T-complex protein 11 Hex_IIIa PF02455.11 KFX88667.1 - 0.33 9.5 6.8 0.83 8.2 4.7 1.6 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Mito_carr PF00153.22 KFX88669.1 - 1.5e-66 220.1 4.8 6.9e-24 83.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF21 PF01595.15 KFX88670.1 - 2.6e-23 82.2 5.1 4.3e-23 81.5 3.5 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 RRM_6 PF14259.1 KFX88670.1 - 7.7e-06 25.8 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFX88670.1 - 0.001 18.6 0.0 0.0022 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX88670.1 - 0.0028 17.4 0.0 0.0069 16.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET PF00856.23 KFX88671.1 - 8.7e-15 55.3 0.0 1.4e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 SET domain Coq4 PF05019.8 KFX88672.1 - 2.1e-97 324.4 0.0 2.4e-97 324.2 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 dsDNA_bind PF01984.15 KFX88673.1 - 7.9e-35 119.0 5.8 9.7e-35 118.7 4.0 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain CD99L2 PF12301.3 KFX88673.1 - 0.038 13.6 1.3 0.038 13.6 0.9 1.9 2 0 0 2 2 2 0 CD99 antigen like protein 2 LigT_PEase PF02834.11 KFX88673.1 - 0.13 12.2 0.2 0.35 10.8 0.1 1.8 1 1 0 1 1 1 0 LigT like Phosphoesterase ApbA_C PF08546.6 KFX88674.1 - 5.5e-22 78.0 0.1 1.1e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KFX88674.1 - 1.6e-16 60.1 0.0 3.1e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sas10_Utp3 PF04000.10 KFX88675.1 - 4e-17 62.1 0.1 4e-17 62.1 0.1 2.1 2 0 0 2 2 2 1 Sas10/Utp3/C1D family RR_TM4-6 PF06459.7 KFX88675.1 - 0.24 11.2 17.0 0.3 10.9 11.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.2 KFX88675.1 - 8.2 3.9 13.5 9.7 3.7 9.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2076 PF09849.4 KFX88676.1 - 1.5e-08 34.9 8.7 1.8e-08 34.7 6.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 KFX88676.1 - 0.00013 21.7 6.5 0.00018 21.3 4.5 1.2 1 0 0 1 1 1 1 CHCH domain UBX PF00789.15 KFX88677.1 - 1.7e-12 47.2 0.0 3.5e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 UBX domain HNF-1_N PF04814.8 KFX88677.1 - 0.027 14.5 2.3 0.058 13.5 1.6 1.6 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus SOBP PF15279.1 KFX88677.1 - 0.38 11.0 2.3 0.59 10.4 1.6 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein DUF1510 PF07423.6 KFX88677.1 - 0.76 9.0 10.2 1.2 8.4 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SURF1 PF02104.10 KFX88678.1 - 1.2e-64 218.1 0.1 5.1e-64 215.9 0.0 1.8 2 0 0 2 2 2 1 SURF1 family CENP-T PF15511.1 KFX88679.1 - 2.5e-100 336.6 32.3 1.4e-99 334.2 12.7 2.1 2 0 0 2 2 2 2 Centromere kinetochore component CENP-T CENP-S PF15630.1 KFX88679.1 - 7.2e-09 35.7 0.0 1.4e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KFX88679.1 - 1.5e-05 24.9 0.0 3.7e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFX88679.1 - 0.00014 21.9 0.0 0.00035 20.6 0.0 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KFX88679.1 - 0.066 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Daxx PF03344.10 KFX88679.1 - 0.075 11.5 8.2 0.13 10.7 5.7 1.2 1 0 0 1 1 1 0 Daxx Family 60KD_IMP PF02096.15 KFX88702.1 - 4e-21 75.6 0.1 5e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein Glycos_transf_1 PF00534.15 KFX88703.1 - 1.4e-21 76.7 0.0 2.1e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KFX88703.1 - 1.2e-09 38.4 0.0 2.4e-08 34.2 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KFX88703.1 - 0.026 14.2 0.0 0.06 13.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Phage_P2_GpE PF06528.7 KFX88703.1 - 0.055 12.9 1.8 1.5 8.2 0.2 2.5 2 0 0 2 2 2 0 Phage P2 GpE Herpes_pp38 PF04846.8 KFX88703.1 - 0.1 11.9 0.1 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein Pkinase PF00069.20 KFX88706.1 - 2.5e-60 203.8 0.0 3.7e-60 203.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX88706.1 - 3.7e-30 104.8 0.2 1.5e-28 99.5 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFX88706.1 - 0.00014 21.6 0.0 0.00038 20.2 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFX88706.1 - 0.00017 20.9 0.1 0.00034 20.0 0.1 1.4 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.9 KFX88706.1 - 0.00022 20.3 0.0 0.00036 19.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KFX88706.1 - 0.00074 19.1 0.1 0.0012 18.4 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 KFX88706.1 - 0.033 13.1 0.0 0.077 11.9 0.0 1.6 2 0 0 2 2 2 0 Kinase-like YukC PF10140.4 KFX88706.1 - 0.043 12.3 0.0 0.063 11.8 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC YrbL-PhoP_reg PF10707.4 KFX88706.1 - 0.12 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SMC_N PF02463.14 KFX88708.1 - 1.7e-27 96.0 0.2 2.6e-27 95.4 0.1 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KFX88708.1 - 6.6e-18 65.7 0.0 6.6e-18 65.7 0.0 4.5 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 KFX88708.1 - 4.7e-08 33.3 0.0 7.7e-05 22.7 0.0 2.6 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KFX88708.1 - 0.00028 20.3 0.0 0.00057 19.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 KFX88708.1 - 0.037 14.2 0.0 0.19 11.9 0.0 2.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KFX88708.1 - 0.44 10.8 0.0 0.44 10.8 0.0 4.6 3 2 1 4 4 4 0 ABC transporter DUF3290 PF11694.3 KFX88712.1 - 0.054 13.2 0.5 0.094 12.4 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) DUF4293 PF14126.1 KFX88712.1 - 0.15 11.9 5.3 0.03 14.2 1.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) MARVEL PF01284.18 KFX88712.1 - 0.37 10.6 17.1 0.52 10.1 11.8 1.2 1 0 0 1 1 1 0 Membrane-associating domain DUF2085 PF09858.4 KFX88712.1 - 4.2 7.5 6.4 0.88 9.6 0.8 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) Oxidored_q1_N PF00662.15 KFX88712.1 - 4.2 7.0 9.3 11 5.7 0.6 2.7 1 1 1 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus Peptidase_M41 PF01434.13 KFX88714.1 - 6e-75 251.3 0.0 9.9e-75 250.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KFX88714.1 - 3.9e-42 143.5 0.0 9.9e-42 142.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APH PF01636.18 KFX88714.1 - 1.7e-08 34.5 0.0 7.9e-08 32.3 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family FtsH_ext PF06480.10 KFX88714.1 - 7.6e-06 26.0 0.0 2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 KFX88714.1 - 0.00021 21.0 0.0 0.00055 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFX88714.1 - 0.0019 18.3 0.1 0.37 10.9 0.1 2.9 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.7 KFX88714.1 - 0.0056 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KFX88714.1 - 0.0089 16.8 0.0 0.035 14.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFX88714.1 - 0.0093 15.6 1.0 0.037 13.7 0.5 2.2 2 0 0 2 2 2 1 Part of AAA domain TIP49 PF06068.8 KFX88714.1 - 0.012 14.3 0.1 0.021 13.5 0.1 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_16 PF13191.1 KFX88714.1 - 0.024 14.6 0.2 0.24 11.3 0.1 2.6 1 1 1 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 KFX88714.1 - 0.028 13.5 0.0 0.07 12.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_2 PF07724.9 KFX88714.1 - 0.029 14.2 0.0 0.097 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 KFX88714.1 - 0.059 12.7 0.3 0.18 11.1 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KFX88714.1 - 0.078 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KFX88714.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein HNF-1B_C PF04812.8 KFX88721.1 - 0.065 12.5 0.3 0.089 12.0 0.2 1.3 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus Pex14_N PF04695.8 KFX88721.1 - 0.13 12.3 1.0 0.28 11.2 0.1 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1771 PF08590.5 KFX88737.1 - 3.5e-13 49.3 9.5 3.5e-13 49.3 6.6 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF1771) Smr PF01713.16 KFX88737.1 - 2.6e-09 37.1 0.2 1.2e-08 34.9 0.0 2.3 2 0 0 2 2 2 1 Smr domain zf-CCCH PF00642.19 KFX88737.1 - 5.1e-07 29.2 0.6 0.0049 16.5 0.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HBS1_N PF08938.5 KFX88737.1 - 0.00088 19.3 0.0 0.0032 17.5 0.0 1.9 2 0 0 2 2 2 1 HBS1 N-terminus DUF2799 PF10973.3 KFX88739.1 - 10 6.2 6.5 0.87 9.6 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2799) SMN PF06003.7 KFX88740.1 - 5.3e-07 29.0 5.1 0.00013 21.1 0.4 2.2 1 1 0 2 2 2 2 Survival motor neuron protein (SMN) Copper-bind PF00127.15 KFX88741.1 - 0.0053 16.9 0.5 0.015 15.5 0.3 1.7 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.12 KFX88741.1 - 0.034 13.9 0.8 0.19 11.5 0.5 2.1 1 1 0 1 1 1 0 Plastocyanin-like domain Syndecan PF01034.15 KFX88742.1 - 0.019 14.5 0.3 0.049 13.2 0.2 1.6 1 0 0 1 1 1 0 Syndecan domain Guanylate_kin PF00625.16 KFX88743.1 - 2.4e-56 190.0 0.1 3.5e-56 189.5 0.1 1.2 1 0 0 1 1 1 1 Guanylate kinase DEAD PF00270.24 KFX88743.1 - 8.1e-09 35.1 0.6 2.7e-08 33.4 0.1 2.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_18 PF13238.1 KFX88743.1 - 4.1e-05 23.9 0.1 0.00013 22.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFX88743.1 - 0.00012 21.9 0.0 0.00056 19.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFX88743.1 - 0.00015 22.5 0.1 0.00036 21.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFX88743.1 - 0.0012 18.9 0.1 0.0062 16.6 0.0 2.2 1 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KFX88743.1 - 0.0029 17.6 0.1 0.22 11.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFX88743.1 - 0.0043 16.2 0.0 0.008 15.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Thymidylate_kin PF02223.12 KFX88743.1 - 0.016 14.5 0.4 0.21 10.9 0.3 2.1 1 1 0 1 1 1 0 Thymidylate kinase AAA PF00004.24 KFX88743.1 - 0.021 15.0 0.2 0.069 13.3 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Helicase_C PF00271.26 KFX88743.1 - 0.033 14.0 0.0 0.076 12.8 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain DUF1895 PF08988.5 KFX88743.1 - 0.1 12.6 0.3 0.1 12.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1895) ABC_tran PF00005.22 KFX88743.1 - 0.11 12.7 0.2 0.27 11.5 0.1 1.8 1 1 0 1 1 1 0 ABC transporter YrhK PF14145.1 KFX88748.1 - 0.23 11.1 5.2 0.46 10.1 1.1 2.7 2 1 0 2 2 2 0 YrhK-like protein Flavodoxin_1 PF00258.20 KFX88752.1 - 5.4e-10 39.4 0.0 7.6e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 KFX88752.1 - 5e-09 35.8 0.1 6.4e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KFX88752.1 - 0.00038 20.0 0.0 0.00049 19.6 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Bacteriocin_IIc PF10439.4 KFX88752.1 - 4.8 7.3 8.4 13 5.9 3.9 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide C2 PF00168.25 KFX88759.1 - 7.9e-14 51.2 0.0 1.4e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain ICL PF00463.16 KFX88760.1 - 2.5e-280 930.1 1.2 2.9e-280 929.9 0.9 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KFX88760.1 - 4.2e-12 45.8 0.1 2.5e-11 43.2 0.0 2.1 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Mus7 PF09462.5 KFX88762.1 - 2.3e-56 191.9 0.0 3.1e-56 191.5 0.0 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family PHO4 PF01384.15 KFX88762.1 - 0.084 11.5 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphate transporter family DUF3726 PF12525.3 KFX88762.1 - 0.14 11.9 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3726) Cys_Met_Meta_PP PF01053.15 KFX88763.1 - 6.5e-57 192.5 0.0 1.4e-56 191.4 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KFX88763.1 - 0.00029 19.8 0.0 0.00072 18.6 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KFX88763.1 - 0.028 13.1 0.0 0.047 12.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V FMN_bind_2 PF04299.7 KFX88764.1 - 8.5e-55 184.8 0.0 1.1e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Fungal_trans_2 PF11951.3 KFX88765.1 - 4.4e-46 157.2 6.5 5.4e-46 156.9 4.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain GBA2_N PF12215.3 KFX88766.1 - 0.03 13.4 0.1 0.046 12.8 0.1 1.3 1 0 0 1 1 1 0 beta-Glucocerebrosidase 2 N terminal PrgI PF12666.2 KFX88767.1 - 1.2 9.3 5.9 0.12 12.5 0.5 2.1 2 1 0 2 2 2 0 PrgI family protein Swi3 PF07962.7 KFX88777.1 - 1.9e-28 97.8 0.0 3e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 TPP_enzyme_N PF02776.13 KFX88782.1 - 1.8e-37 128.4 0.1 8.1e-37 126.3 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KFX88782.1 - 7.2e-21 74.3 0.1 6.2e-20 71.3 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KFX88782.1 - 5.1e-20 71.6 0.0 1.3e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Grp1_Fun34_YaaH PF01184.14 KFX88798.1 - 7.6e-90 299.8 15.9 9.1e-90 299.5 11.0 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Cyclin_N PF00134.18 KFX88799.1 - 7.3e-34 116.0 0.2 1.3e-33 115.2 0.1 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFX88799.1 - 2.8e-14 53.0 0.3 8.1e-14 51.5 0.2 1.8 1 1 0 1 1 1 1 Cyclin, C-terminal domain vWF_A PF12450.3 KFX88803.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor Isochorismatase PF00857.15 KFX88804.1 - 3.4e-33 115.0 0.0 3.8e-33 114.8 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family MFS_1 PF07690.11 KFX88805.1 - 1.6e-48 165.1 15.8 1.6e-48 165.1 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX88805.1 - 1.6e-11 43.4 7.3 1.6e-11 43.4 5.1 3.3 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.8 KFX88805.1 - 3e-06 25.6 2.2 6.8e-06 24.4 1.5 1.6 1 0 0 1 1 1 1 Transmembrane secretion effector DUF791 PF05631.9 KFX88805.1 - 0.00048 18.9 3.3 0.0024 16.6 0.4 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF791) MFS_1_like PF12832.2 KFX88805.1 - 0.086 12.6 10.9 0.16 11.8 0.1 3.3 3 1 1 4 4 4 0 MFS_1 like family ATG22 PF11700.3 KFX88805.1 - 0.25 9.7 0.0 0.25 9.7 0.0 3.5 3 1 1 4 4 4 0 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KFX88806.1 - 9.6e-36 123.2 33.7 2.9e-34 118.3 22.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Snf7 PF03357.16 KFX88808.1 - 2.1e-08 33.7 0.1 3.2e-08 33.1 0.1 1.3 1 1 0 1 1 1 1 Snf7 Spore_III_AF PF09581.5 KFX88808.1 - 0.046 13.5 0.1 0.067 13.0 0.1 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) DSHCT PF08148.7 KFX88809.1 - 2.7e-59 199.4 0.6 5.2e-59 198.5 0.4 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KFX88809.1 - 5.8e-21 74.7 0.1 1.3e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX88809.1 - 1.2e-06 28.2 0.0 3.4e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 KFX88809.1 - 0.013 14.6 0.1 0.041 13.0 0.0 1.8 2 0 0 2 2 2 0 rRNA-processing arch domain ResIII PF04851.10 KFX88809.1 - 0.017 14.9 0.1 0.21 11.3 0.0 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2890 PF11081.3 KFX88809.1 - 0.27 11.2 6.9 0.55 10.2 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CHCH PF06747.8 KFX88810.1 - 9.1e-10 38.1 11.4 2.3e-08 33.7 1.4 2.6 3 0 0 3 3 3 2 CHCH domain Cmc1 PF08583.5 KFX88810.1 - 0.16 11.7 10.7 1.7 8.4 1.6 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like TF_Otx PF03529.8 KFX88810.1 - 0.61 10.3 2.7 1.3 9.3 1.9 1.6 1 1 0 1 1 1 0 Otx1 transcription factor Pet191_N PF10203.4 KFX88810.1 - 0.82 9.7 7.1 1.4 9.0 3.2 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 KFX88810.1 - 2.6 8.1 9.9 5.8 7.0 0.7 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb Fungal_trans PF04082.13 KFX88812.1 - 1.7e-28 99.2 0.0 2.5e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX88812.1 - 1.4e-09 37.6 10.9 2.4e-09 36.9 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dynamin_N PF00350.18 KFX88815.1 - 2.1e-30 105.7 0.0 4.6e-30 104.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KFX88815.1 - 4.1e-17 61.8 1.2 2.3e-16 59.4 0.8 2.0 1 1 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 KFX88815.1 - 0.00064 19.6 0.0 0.0025 17.7 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.1 KFX88815.1 - 0.018 14.9 0.0 0.056 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KFX88815.1 - 0.022 15.2 0.1 0.084 13.3 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein Nucleoporin_FG PF13634.1 KFX88815.1 - 0.038 14.2 17.1 0.066 13.4 11.9 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeat region GED PF02212.13 KFX88815.1 - 0.061 13.2 0.1 0.26 11.1 0.1 2.1 1 0 0 1 1 1 0 Dynamin GTPase effector domain Imm27 PF15573.1 KFX88815.1 - 0.074 12.2 0.9 0.14 11.3 0.1 1.8 2 0 0 2 2 2 0 Immunity protein 27 AAA_29 PF13555.1 KFX88815.1 - 0.13 11.8 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cellulase PF00150.13 KFX88816.1 - 1.3e-14 54.0 2.5 3.1e-09 36.4 0.5 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) TPR_11 PF13414.1 KFX88817.1 - 3.9e-48 160.9 27.9 3.1e-06 26.7 0.0 12.4 9 3 4 13 13 13 11 TPR repeat TPR_16 PF13432.1 KFX88817.1 - 2.7e-39 133.0 38.2 4.6e-07 30.3 2.8 13.3 13 2 2 15 15 12 9 Tetratricopeptide repeat TPR_2 PF07719.12 KFX88817.1 - 1.3e-31 105.8 40.3 0.0062 16.3 0.0 16.1 17 0 0 17 17 17 9 Tetratricopeptide repeat TPR_14 PF13428.1 KFX88817.1 - 5.9e-31 104.1 35.7 0.0034 17.8 0.0 15.6 12 5 5 17 17 15 8 Tetratricopeptide repeat TPR_17 PF13431.1 KFX88817.1 - 3.9e-28 95.2 14.0 0.067 13.4 0.0 15.9 16 1 0 16 16 15 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFX88817.1 - 4.8e-27 94.0 19.5 0.0016 18.7 0.0 11.4 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_1 PF00515.23 KFX88817.1 - 3.2e-25 86.6 23.4 0.00091 18.7 0.0 13.6 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_12 PF13424.1 KFX88817.1 - 2.5e-24 85.0 23.9 4.9e-06 26.3 0.0 11.8 7 6 7 14 14 14 8 Tetratricopeptide repeat TPR_8 PF13181.1 KFX88817.1 - 1.6e-17 61.8 10.4 0.063 13.0 0.0 12.0 11 1 1 12 12 11 3 Tetratricopeptide repeat TPR_6 PF13174.1 KFX88817.1 - 3.5e-14 52.2 19.5 0.02 15.3 0.0 13.0 15 0 0 15 15 12 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFX88817.1 - 3.3e-12 45.2 18.9 0.083 12.7 0.0 12.2 13 0 0 13 13 12 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFX88817.1 - 9.7e-10 38.1 14.9 0.0014 18.4 0.1 7.0 7 1 1 8 8 6 3 Tetratricopeptide repeat TPR_20 PF14561.1 KFX88817.1 - 2.9e-06 27.3 9.4 2.6 8.2 0.0 7.6 7 1 1 8 8 8 1 Tetratricopeptide repeat Apc3 PF12895.2 KFX88817.1 - 3.1e-05 24.0 20.1 0.012 15.7 0.0 7.3 6 2 2 8 8 8 1 Anaphase-promoting complex, cyclosome, subunit 3 Tcf25 PF04910.9 KFX88817.1 - 0.0018 17.2 0.1 0.17 10.8 0.0 3.1 3 0 0 3 3 3 1 Transcriptional repressor TCF25 ChAPs PF09295.5 KFX88817.1 - 0.004 15.9 0.2 9.1 4.9 0.0 4.2 4 0 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) Coatomer_WDAD PF04053.9 KFX88817.1 - 0.0086 14.9 0.0 0.024 13.4 0.0 1.7 1 0 0 1 1 1 1 Coatomer WD associated region DUF2225 PF09986.4 KFX88817.1 - 0.0087 15.5 0.7 4.1 6.8 0.0 2.8 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2225) Adaptin_N PF01602.15 KFX88818.1 - 2e-149 498.3 4.1 2.8e-149 497.8 2.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KFX88818.1 - 1.5e-25 90.0 0.3 5.3e-24 85.0 0.1 2.5 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KFX88818.1 - 4.3e-18 65.3 0.9 3.7e-06 27.1 0.0 5.3 2 2 3 5 5 5 5 HEAT repeats HEAT PF02985.17 KFX88818.1 - 8.3e-12 44.1 4.3 0.016 15.2 0.0 6.5 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 KFX88818.1 - 0.00075 19.9 0.7 0.89 10.1 0.0 5.1 6 1 1 7 7 7 1 HEAT-like repeat CLASP_N PF12348.3 KFX88818.1 - 0.0012 18.2 0.3 2.1 7.6 0.0 3.5 3 1 1 4 4 4 2 CLASP N terminal UNC45-central PF11701.3 KFX88818.1 - 0.0037 16.9 0.7 2.1 7.9 0.0 2.5 2 0 0 2 2 2 2 Myosin-binding striated muscle assembly central Arm PF00514.18 KFX88818.1 - 0.027 14.2 0.3 8.3 6.4 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 KFX88818.1 - 0.033 13.9 0.0 0.55 9.9 0.0 2.6 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Rep_fac_C PF08542.6 KFX88818.1 - 0.11 12.4 0.1 21 5.1 0.0 3.1 1 1 1 2 2 2 0 Replication factor C C-terminal domain DUF3593 PF12159.3 KFX88820.1 - 0.093 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3593) Pro_CA PF00484.14 KFX88821.1 - 1.1e-28 100.1 0.0 1.4e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase BolA PF01722.13 KFX88822.1 - 4.2e-21 74.6 0.0 5.7e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein NIF3 PF01784.13 KFX88823.1 - 8.7e-58 195.7 0.0 1.1e-57 195.3 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Vps51 PF08700.6 KFX88824.1 - 4.1e-28 97.0 1.2 6.8e-28 96.3 0.1 1.9 2 0 0 2 2 2 1 Vps51/Vps67 Dor1 PF04124.7 KFX88824.1 - 3.8e-08 32.1 2.0 5.6e-08 31.6 1.4 1.1 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.4 KFX88824.1 - 0.0042 17.0 0.2 0.014 15.3 0.0 1.8 1 1 1 2 2 2 1 Golgi transport complex subunit 5 BBP1_C PF15272.1 KFX88824.1 - 0.0093 15.5 0.4 0.018 14.5 0.1 1.5 1 1 0 1 1 1 1 Spindle pole body component BBP1, C-terminal Sec5 PF15469.1 KFX88824.1 - 0.016 14.9 0.1 0.053 13.2 0.0 1.9 2 0 0 2 2 2 0 Exocyst complex component Sec5 UBN_AB PF14075.1 KFX88824.1 - 0.018 14.7 1.2 0.027 14.1 0.8 1.3 1 0 0 1 1 1 0 Ubinuclein conserved middle domain DUF365 PF04033.7 KFX88824.1 - 0.024 14.6 0.0 0.059 13.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Stimulus_sens_1 PF13756.1 KFX88824.1 - 0.048 14.0 0.7 0.23 11.8 0.1 2.1 1 1 1 2 2 2 0 Stimulus-sensing domain NYD-SP28_assoc PF14775.1 KFX88824.1 - 0.05 13.3 0.5 0.13 11.9 0.3 1.7 1 0 0 1 1 1 0 Sperm tail C-terminal domain SSFA2_C PF14723.1 KFX88824.1 - 0.06 13.0 0.5 0.15 11.7 0.4 1.6 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus ATP-synt_ab PF00006.20 KFX88824.1 - 0.098 12.1 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Toxin_39 PF15500.1 KFX88824.1 - 2.1 8.5 5.3 8.2 6.6 0.0 2.5 1 1 1 2 2 2 0 Putative RNase-like toxin FUSC PF04632.7 KFX88824.1 - 5 5.4 8.3 11 4.2 5.6 1.5 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF1767 PF08585.7 KFX88825.1 - 2.4e-07 30.9 0.0 3.4e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) Xpo1 PF08389.7 KFX88826.1 - 2.1e-07 30.9 0.7 2.5e-05 24.2 0.1 2.9 2 0 0 2 2 2 2 Exportin 1-like protein TLD PF07534.11 KFX88827.1 - 1.9e-26 92.7 0.0 1.1e-14 54.5 0.0 2.3 2 0 0 2 2 2 2 TLD Evr1_Alr PF04777.8 KFX88827.1 - 0.00034 20.4 0.9 0.0005 19.9 0.1 1.6 2 0 0 2 2 2 1 Erv1 / Alr family AAA PF00004.24 KFX88828.1 - 3.1e-40 137.4 0.0 6.9e-40 136.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PRKCSH PF07915.8 KFX88828.1 - 1.2e-15 58.0 0.1 4.2e-15 56.3 0.1 2.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein AAA_22 PF13401.1 KFX88828.1 - 4.1e-05 23.7 0.0 0.0019 18.3 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFX88828.1 - 0.00016 21.3 0.1 0.00084 19.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KFX88828.1 - 0.00087 19.2 0.0 0.0025 17.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KFX88828.1 - 0.001 19.1 0.0 0.0038 17.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 KFX88828.1 - 0.0057 15.6 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KFX88828.1 - 0.014 16.1 0.0 0.049 14.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KFX88828.1 - 0.023 14.4 0.1 0.059 13.1 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain RuvB_N PF05496.7 KFX88828.1 - 0.028 13.4 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KFX88828.1 - 0.058 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFX88828.1 - 0.082 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KFX88828.1 - 0.086 12.7 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KFX88828.1 - 0.15 12.0 0.0 0.61 10.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain Cpn60_TCP1 PF00118.19 KFX88829.1 - 1.6e-139 465.6 16.6 2e-139 465.3 11.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 KFX88829.1 - 0.022 14.2 0.0 0.055 12.9 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X DUF3924 PF13062.1 KFX88829.1 - 0.09 12.6 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) WD40 PF00400.27 KFX88832.1 - 2.7e-61 201.4 21.3 1e-10 41.0 0.2 8.3 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 KFX88832.1 - 3.4e-12 45.9 0.3 6.9e-12 44.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX88832.1 - 1.2e-10 40.7 0.5 3.6e-10 39.2 0.1 2.0 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.3 KFX88832.1 - 1.2e-09 36.8 9.2 0.019 13.1 0.1 5.4 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFX88832.1 - 0.012 14.3 1.5 1.1 7.9 0.0 2.3 1 1 1 2 2 2 0 Nup133 N terminal like PRANC PF09372.5 KFX88832.1 - 0.033 14.1 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 PRANC domain Peptidase_M14 PF00246.19 KFX88833.1 - 4.3e-64 216.8 0.0 5.7e-64 216.4 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Glyco_hydro_65m PF03632.10 KFX88841.1 - 2.2e-76 256.9 2.7 2.9e-75 253.2 1.9 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 KFX88841.1 - 5.4e-33 114.3 0.3 1.5e-32 112.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain DUF1447 PF07288.6 KFX88841.1 - 0.095 12.5 0.2 14 5.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1447) RhoGEF PF00621.15 KFX88843.1 - 5.6e-26 91.5 0.0 1.1e-25 90.5 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.3 KFX88843.1 - 0.013 14.9 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) Glyco_trans_1_3 PF13528.1 KFX88843.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 DUF2036 PF09724.4 KFX88844.1 - 9.5e-07 28.2 0.0 1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Arf PF00025.16 KFX88848.1 - 0.00059 19.1 0.5 0.0034 16.6 0.3 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family cobW PF02492.14 KFX88848.1 - 0.011 15.1 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Zea_mays_MuDR PF05928.6 KFX88848.1 - 0.057 12.8 0.0 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) Acyl-CoA_dh_2 PF08028.6 KFX88858.1 - 0.058 13.6 5.4 0.83 9.9 0.1 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain ThiF PF00899.16 KFX88859.1 - 6.4e-16 58.4 0.1 1.2e-15 57.5 0.1 1.5 1 0 0 1 1 1 1 ThiF family DUF2431 PF10354.4 KFX88860.1 - 7.8e-56 188.5 0.0 1.1e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) F-box PF00646.28 KFX88864.1 - 1.7e-07 30.7 0.1 3.7e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFX88864.1 - 1.3e-05 24.8 0.2 5.1e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 F-box-like V-ATPase_C PF03223.10 KFX88867.1 - 3.7e-117 391.3 0.0 4.2e-117 391.2 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C APS_kinase PF01583.15 KFX88868.1 - 3.4e-68 228.2 0.0 4.1e-68 227.9 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.1 KFX88868.1 - 8.4e-07 29.8 0.0 1.5e-06 29.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFX88868.1 - 7.9e-06 25.8 0.0 1.2e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFX88868.1 - 6.4e-05 23.2 0.0 0.00011 22.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 KFX88868.1 - 0.00059 19.1 0.0 0.00072 18.8 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 KFX88868.1 - 0.013 14.9 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KFX88868.1 - 0.043 12.9 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin CPT PF07931.7 KFX88868.1 - 0.075 12.6 0.0 0.16 11.6 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein 6PF2K PF01591.13 KFX88868.1 - 0.1 11.6 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_16 PF13191.1 KFX88868.1 - 0.13 12.2 0.1 0.26 11.2 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain PRK PF00485.13 KFX88868.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Abhydrolase_3 PF07859.8 KFX88869.1 - 2.5e-05 23.9 0.0 3.1e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KFX88869.1 - 0.0026 16.4 0.0 0.0026 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 KFX88870.1 - 0.001 18.6 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KFX88870.1 - 0.018 13.7 0.0 0.022 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Transferase PF02458.10 KFX88871.1 - 0.00056 18.4 0.0 0.0041 15.6 0.0 1.9 1 1 0 1 1 1 1 Transferase family Lipase_GDSL_2 PF13472.1 KFX88872.1 - 5.4e-13 49.4 0.0 1.2e-12 48.3 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFX88872.1 - 3e-11 43.5 0.0 4.9e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase VCBS PF13517.1 KFX88872.1 - 6.2e-06 26.4 16.8 6.2e-05 23.2 4.2 3.0 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_3 PF14606.1 KFX88872.1 - 0.026 14.2 0.1 0.44 10.2 0.0 2.2 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family FG-GAP PF01839.18 KFX88872.1 - 0.59 9.9 15.3 3 7.6 3.9 3.4 3 0 0 3 3 3 0 FG-GAP repeat HATPase_c PF02518.21 KFX88874.1 - 5.5e-29 100.1 0.0 2.1e-28 98.2 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KFX88874.1 - 3.7e-21 75.2 0.1 1.6e-20 73.1 0.1 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KFX88874.1 - 8.4e-20 70.5 0.2 3.2e-19 68.6 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 KFX88874.1 - 3.3e-14 53.3 0.7 2e-13 50.7 0.5 2.4 1 1 0 1 1 1 1 AAA ATPase domain GAF_2 PF13185.1 KFX88874.1 - 6.1e-09 36.5 0.0 1.7e-08 35.0 0.0 1.9 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 KFX88874.1 - 1.2e-08 34.4 0.0 2.6e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain GAF_3 PF13492.1 KFX88874.1 - 2.6e-05 24.3 0.0 6.2e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 GAF domain NACHT PF05729.7 KFX88874.1 - 0.0043 16.7 0.0 1.2 8.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain ArgK PF03308.11 KFX88874.1 - 0.051 12.3 0.1 0.098 11.4 0.1 1.4 1 0 0 1 1 1 0 ArgK protein TPR_8 PF13181.1 KFX88874.1 - 0.14 11.9 0.0 1.4 8.8 0.0 2.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Cript PF10235.4 KFX88884.1 - 8e-27 93.4 8.7 1.3e-26 92.7 6.0 1.3 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT DZR PF12773.2 KFX88884.1 - 0.0038 17.0 4.9 0.0038 17.0 3.4 2.4 3 0 0 3 3 3 1 Double zinc ribbon zf-ribbon_3 PF13248.1 KFX88884.1 - 3.6 6.9 9.3 12 5.2 0.4 3.4 2 1 1 3 3 3 0 zinc-ribbon domain Pacifastin_I PF05375.8 KFX88884.1 - 4.8 6.7 11.9 13 5.4 3.8 2.5 1 1 1 2 2 2 0 Pacifastin inhibitor (LCMII) RRN7 PF11781.3 KFX88884.1 - 6.5 6.3 7.4 12 5.5 0.9 2.8 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Fungal_trans PF04082.13 KFX88888.1 - 5.3e-17 61.5 0.1 8.4e-17 60.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX88888.1 - 6e-10 38.8 9.8 9.6e-10 38.2 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain V_ATPase_I PF01496.14 KFX88891.1 - 5.3e-293 973.6 0.0 7.4e-293 973.1 0.0 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Prenyltransf PF01255.14 KFX88891.1 - 1.1e-82 276.5 0.0 3.7e-82 274.7 0.0 1.8 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase Filament PF00038.16 KFX88891.1 - 0.025 14.0 4.5 1.2 8.5 0.0 2.4 2 1 0 2 2 2 0 Intermediate filament protein Transposase_22 PF02994.9 KFX88891.1 - 0.089 11.2 1.2 0.16 10.4 0.3 1.7 2 0 0 2 2 2 0 L1 transposable element IncA PF04156.9 KFX88891.1 - 0.2 11.2 4.5 0.14 11.7 0.7 2.2 2 0 0 2 2 2 0 IncA protein Baculo_PEP_C PF04513.7 KFX88891.1 - 0.25 11.1 1.3 3.9 7.2 0.0 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 KFX88891.1 - 0.33 10.0 1.7 4 6.5 0.1 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Laminin_II PF06009.7 KFX88891.1 - 0.34 10.6 1.6 11 5.7 0.1 2.5 2 0 0 2 2 2 0 Laminin Domain II DivIC PF04977.10 KFX88891.1 - 0.38 10.2 3.2 0.28 10.6 0.1 2.4 2 0 0 2 2 2 0 Septum formation initiator CENP-F_leu_zip PF10473.4 KFX88891.1 - 2.4 8.0 5.2 2.2 8.1 1.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1751 PF08551.5 KFX88892.1 - 0.00011 22.4 0.2 0.00021 21.5 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 KFX88892.1 - 0.00073 19.5 1.9 0.0015 18.5 1.3 1.5 1 0 0 1 1 1 1 Rhomboid family DPBB_1 PF03330.13 KFX88893.1 - 5.4e-09 35.9 0.0 1.6e-08 34.4 0.0 1.9 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel ING PF12998.2 KFX88893.1 - 1.2e-08 35.2 0.1 6.3e-08 32.8 0.1 2.1 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KFX88893.1 - 5.5e-07 29.1 6.7 1.1e-06 28.1 4.6 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 KFX88893.1 - 0.027 14.6 0.7 0.074 13.2 0.5 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.1 KFX88893.1 - 0.16 11.3 1.2 0.32 10.3 0.8 1.5 1 0 0 1 1 1 0 PHD-finger Methyltransf_6 PF03737.10 KFX88894.1 - 3.4e-15 56.2 4.5 4.5e-15 55.8 3.1 1.2 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase ChuX_HutX PF06228.8 KFX88894.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Haem utilisation ChuX/HutX Orbi_VP7 PF00897.12 KFX88894.1 - 0.23 10.3 0.5 0.25 10.2 0.4 1.1 1 0 0 1 1 1 0 Orbivirus inner capsid protein VP7 ERCC4 PF02732.10 KFX88895.1 - 2.4e-23 82.4 0.1 5.9e-23 81.2 0.1 1.6 2 0 0 2 2 2 1 ERCC4 domain ERCC4 PF02732.10 KFX88896.1 - 3.9e-10 39.6 0.0 7.6e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 KFX88896.1 - 0.00033 20.7 0.0 0.00058 19.9 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HTH_45 PF14947.1 KFX88896.1 - 0.054 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix PGM_PMM_I PF02878.11 KFX88897.1 - 6e-19 67.9 0.1 4.4e-09 35.9 0.0 2.8 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KFX88897.1 - 1.3e-15 57.5 0.1 6.1e-15 55.4 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KFX88897.1 - 5.8e-14 51.8 0.8 2e-13 50.1 0.4 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 KFX88897.1 - 0.00016 21.7 0.1 0.0005 20.0 0.1 2.0 1 1 1 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Lum_binding PF00677.12 KFX88898.1 - 1.8e-38 130.3 0.4 3.7e-20 71.6 0.0 2.4 2 0 0 2 2 2 2 Lumazine binding domain F-box-like PF12937.2 KFX88898.1 - 0.012 15.3 0.1 0.03 14.0 0.1 1.7 1 0 0 1 1 1 0 F-box-like F-box-like_2 PF13013.1 KFX88898.1 - 0.96 9.2 3.3 5.1 6.8 0.0 2.8 3 0 0 3 3 3 0 F-box-like domain PINIT PF14324.1 KFX88901.1 - 3.5e-39 134.1 0.1 6.4e-39 133.3 0.1 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 KFX88901.1 - 2.7e-21 74.7 5.6 5.5e-21 73.8 3.9 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KFX88901.1 - 1.9e-05 24.0 1.3 4.8e-05 22.8 0.9 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.10 KFX88901.1 - 0.014 14.9 0.7 0.054 13.0 0.1 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C3HC4_4 PF15227.1 KFX88901.1 - 0.36 10.7 2.3 0.83 9.5 1.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Aldo_ket_red PF00248.16 KFX88902.1 - 2.4e-57 193.9 0.0 2.8e-57 193.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Patatin PF01734.17 KFX88911.1 - 1.4e-16 61.0 0.0 2.4e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Yip1 PF04893.12 KFX88916.1 - 0.0028 17.2 3.7 0.0041 16.6 2.6 1.2 1 0 0 1 1 1 1 Yip1 domain DctQ PF04290.7 KFX88916.1 - 0.024 14.3 2.1 0.024 14.3 1.4 2.3 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Phage_holin_1 PF04531.8 KFX88916.1 - 0.72 9.9 5.7 0.25 11.4 1.8 1.7 2 0 0 2 2 2 0 Bacteriophage holin DUF2975 PF11188.3 KFX88916.1 - 2.2 7.9 9.6 7.5 6.2 5.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) ECH PF00378.15 KFX88918.1 - 4.2e-16 58.8 0.0 5.1e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KFX88918.1 - 0.00021 21.1 0.0 0.87 9.3 0.0 2.4 2 0 0 2 2 2 2 Peptidase family S49 Glycos_transf_1 PF00534.15 KFX88919.1 - 1e-33 116.2 0.0 2.2e-33 115.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KFX88919.1 - 5.6e-08 33.0 1.4 8.1e-08 32.5 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.1 KFX88919.1 - 1.3e-07 31.4 0.0 9.6e-07 28.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 KFX88919.1 - 5.7e-07 29.7 0.0 1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KFX88919.1 - 5.8e-07 29.7 0.2 8e-05 22.8 0.1 3.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Bul1_N PF04425.7 KFX88927.1 - 0.097 11.2 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Bul1 N terminus zf-H2C2_2 PF13465.1 KFX88928.1 - 3.2e-10 39.7 9.9 2.5e-07 30.6 0.4 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFX88928.1 - 7.1e-10 38.6 7.0 3.2e-06 27.1 0.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX88928.1 - 7.5e-06 25.9 5.2 0.0057 16.9 0.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger SprT-like PF10263.4 KFX88928.1 - 0.053 13.1 0.9 0.083 12.5 0.6 1.4 1 0 0 1 1 1 0 SprT-like family zf-C2HC_2 PF13913.1 KFX88928.1 - 0.076 12.6 0.6 0.076 12.6 0.4 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.10 KFX88928.1 - 0.1 12.3 3.6 5 6.9 0.5 2.5 1 1 1 2 2 2 0 BED zinc finger zf-met PF12874.2 KFX88928.1 - 0.32 11.2 0.3 0.32 11.2 0.2 2.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Rep_fac-A_C PF08646.5 KFX88928.1 - 0.52 10.0 1.9 0.56 9.9 0.1 1.8 2 0 0 2 2 2 0 Replication factor-A C terminal domain zf-met2 PF12907.2 KFX88934.1 - 1.8e-15 56.5 3.7 2.5e-15 56.1 2.5 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 KFX88934.1 - 6.1e-05 23.6 9.8 9.5e-05 23.0 6.8 1.3 1 0 0 1 1 1 1 4F5 protein family LUC7 PF03194.10 KFX88934.1 - 0.068 12.6 0.6 0.075 12.5 0.4 1.0 1 0 0 1 1 1 0 LUC7 N_terminus SR-25 PF10500.4 KFX88934.1 - 0.087 12.2 2.0 0.098 12.1 1.4 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Iso_dh PF00180.15 KFX88964.1 - 3.4e-71 240.0 0.0 4.5e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ino80_Iec3 PF14612.1 KFX88964.1 - 4.4e-52 177.4 0.3 8.9e-52 176.4 0.2 1.5 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling DUF2543 PF10820.3 KFX88964.1 - 0.11 12.4 0.7 0.53 10.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2543) RRM_1 PF00076.17 KFX88965.1 - 9.9e-24 82.7 0.7 1.3e-12 47.1 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX88965.1 - 1.9e-22 79.0 0.0 5.5e-10 39.0 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX88965.1 - 8e-08 32.0 0.0 0.0079 16.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAN_3 PF08277.7 KFX88965.1 - 0.072 12.7 0.0 0.22 11.1 0.0 1.8 1 0 0 1 1 1 0 PAN-like domain DUF2407 PF10302.4 KFX88965.1 - 0.22 11.7 10.5 0.33 11.1 0.0 3.4 3 0 0 3 3 3 0 DUF2407 ubiquitin-like domain zf-3CxxC PF13695.1 KFX88967.1 - 8.7e-21 73.9 1.1 1.9e-20 72.9 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding domain Pneumo_att_G PF05539.6 KFX88967.1 - 2.5 7.3 8.5 3.1 7.0 5.9 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G PsbW PF07123.7 KFX88967.1 - 3.1 7.8 6.3 5.3 7.1 4.4 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) CP2 PF04516.10 KFX88970.1 - 1e-70 237.4 0.0 1.6e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor TMF_TATA_bd PF12325.3 KFX88976.1 - 4.5e-40 136.1 10.8 4.5e-40 136.1 7.5 5.9 3 2 3 6 6 6 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 KFX88976.1 - 3.5e-19 68.3 12.8 3.5e-19 68.3 8.9 7.6 5 3 2 7 7 7 1 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 KFX88976.1 - 0.0026 17.0 21.5 0.067 12.3 1.9 3.7 3 1 0 3 3 3 3 Reovirus sigma C capsid protein Sterile PF03015.14 KFX88976.1 - 0.009 16.2 0.1 0.03 14.5 0.1 1.9 1 0 0 1 1 1 1 Male sterility protein Filament PF00038.16 KFX88976.1 - 0.012 15.1 76.0 0.018 14.5 19.8 4.1 2 1 2 4 4 4 0 Intermediate filament protein Cast PF10174.4 KFX88976.1 - 6.1 4.7 84.8 1.4 6.8 27.0 3.6 2 1 1 3 3 3 0 RIM-binding protein of the cytomatrix active zone WD40_alt PF14077.1 KFX88976.1 - 6.9 6.3 13.0 0.2 11.2 0.5 3.8 4 0 0 4 4 4 0 Alternative WD40 repeat motif Ank_2 PF12796.2 KFX88977.1 - 2.1e-48 162.5 0.7 2.3e-19 69.4 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFX88977.1 - 1.2e-38 129.0 0.3 6.8e-08 31.9 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 KFX88977.1 - 2.2e-38 129.3 1.4 7.8e-09 35.4 0.1 5.3 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFX88977.1 - 1.3e-36 124.3 5.3 1.5e-08 34.9 0.0 5.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX88977.1 - 3.1e-31 104.3 0.1 0.00025 21.0 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat WD40 PF00400.27 KFX88978.1 - 1.1e-52 174.0 10.8 6e-10 38.6 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KFX88978.1 - 0.00014 20.1 4.0 5 5.1 0.0 4.7 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFX88978.1 - 0.14 10.8 0.0 13 4.4 0.0 2.7 1 1 1 2 2 2 0 Nup133 N terminal like AAA PF00004.24 KFX88979.1 - 1.8e-14 54.0 0.0 5e-14 52.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFX88979.1 - 1.8e-10 41.1 0.0 1.1e-09 38.5 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain BAH PF01426.13 KFX88979.1 - 6.8e-10 38.7 0.0 6.5e-09 35.5 0.0 2.3 2 0 0 2 2 2 1 BAH domain AAA_22 PF13401.1 KFX88979.1 - 2.3e-09 37.4 0.0 2.5e-08 34.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KFX88979.1 - 9.5e-05 23.2 0.2 0.0015 19.3 0.0 3.0 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KFX88979.1 - 0.0018 17.9 0.0 0.0054 16.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 KFX88979.1 - 0.0033 16.4 0.0 0.0057 15.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 KFX88979.1 - 0.0042 16.6 0.1 0.012 15.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KFX88979.1 - 0.0091 15.7 0.0 0.075 12.7 0.0 2.4 2 1 0 2 2 2 1 Archaeal ATPase TAFII28 PF04719.9 KFX88979.1 - 0.011 15.5 0.0 0.036 13.8 0.0 1.9 1 0 0 1 1 1 0 hTAFII28-like protein conserved region AAA_18 PF13238.1 KFX88979.1 - 0.013 15.8 0.0 0.04 14.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFX88979.1 - 0.017 14.7 0.0 0.054 13.1 0.0 1.9 1 1 0 1 1 1 0 NACHT domain AAA_32 PF13654.1 KFX88979.1 - 0.017 13.7 0.0 0.036 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFX88979.1 - 0.026 14.6 0.1 0.41 10.8 0.0 2.7 3 0 0 3 3 3 0 RNA helicase AAA_28 PF13521.1 KFX88979.1 - 0.029 14.3 0.0 0.077 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 KFX88979.1 - 0.1 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase RNase_T PF00929.19 KFX88980.1 - 0.1 12.8 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 Exonuclease Prefoldin PF02996.12 KFX88981.1 - 6.4e-26 90.3 0.1 8.8e-26 89.9 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 KFX88981.1 - 0.0035 17.0 2.0 0.41 10.4 0.2 2.1 2 0 0 2 2 2 2 Prefoldin subunit Sec2p PF06428.6 KFX88981.1 - 0.013 15.3 2.5 0.17 11.7 0.3 2.3 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p CCDC155 PF14662.1 KFX88981.1 - 0.017 14.7 0.5 0.017 14.7 0.4 1.8 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 Cep57_MT_bd PF06657.8 KFX88981.1 - 0.026 14.4 0.5 0.058 13.3 0.3 1.5 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Baculo_PEP_C PF04513.7 KFX88981.1 - 0.042 13.6 0.6 0.28 10.9 0.1 2.0 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 KFX88981.1 - 0.094 12.5 0.7 9.7 6.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.5 KFX88981.1 - 0.14 12.2 0.5 13 5.8 0.1 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family tRNA-synt_2b PF00587.20 KFX88982.1 - 4.4e-34 117.5 0.0 5.9e-34 117.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFX88982.1 - 3.3e-11 42.9 0.0 6e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain CBF PF03914.12 KFX88983.1 - 1e-47 161.6 0.0 3.5e-47 159.8 0.0 2.0 2 0 0 2 2 2 1 CBF/Mak21 family 4HBT PF03061.17 KFX88984.1 - 6.2e-11 42.2 0.0 1.2e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily Cupin_2 PF07883.6 KFX88986.1 - 2.9e-15 55.5 0.6 5.1e-15 54.7 0.1 1.6 2 0 0 2 2 2 1 Cupin domain EutQ PF06249.7 KFX88986.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ RRM_1 PF00076.17 KFX88990.1 - 1e-18 66.6 1.3 1.3e-18 66.4 0.2 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX88990.1 - 8e-14 51.3 0.1 1.3e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX88990.1 - 4.1e-09 36.1 0.1 7.7e-09 35.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_43 PF04616.9 KFX89000.1 - 9.1e-32 110.2 2.8 1.1e-31 109.9 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Ribosomal_60s PF00428.14 KFX89002.1 - 0.32 11.4 3.8 0.33 11.3 2.6 1.2 1 0 0 1 1 1 0 60s Acidic ribosomal protein Mito_carr PF00153.22 KFX89003.1 - 2.3e-47 158.6 11.5 2.9e-18 65.3 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein CBS PF00571.23 KFX89004.1 - 0.00094 18.9 0.0 0.43 10.4 0.0 2.8 2 1 0 2 2 2 2 CBS domain DUF3602 PF12223.3 KFX89005.1 - 2.3e-13 50.3 12.5 2e-12 47.2 3.9 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) CENP-B_dimeris PF09026.5 KFX89006.1 - 0.44 10.8 7.8 0.67 10.2 5.4 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HeLo PF14479.1 KFX89008.1 - 2.5e-05 24.1 0.3 0.0071 16.1 0.0 2.2 1 1 1 2 2 2 2 Prion-inhibition and propagation Kdo PF06293.9 KFX89008.1 - 0.016 14.2 0.1 0.037 13.1 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KFX89008.1 - 0.06 12.4 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase zf-C4H2 PF10146.4 KFX89012.1 - 0.014 15.4 2.4 0.025 14.6 1.6 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Chorismate_bind PF00425.13 KFX89013.1 - 2.4e-75 253.1 0.0 3.4e-75 252.6 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Mycoplasma_p37 PF06646.6 KFX89013.1 - 0.15 11.0 0.0 0.37 9.7 0.0 1.6 2 0 0 2 2 2 0 High affinity transport system protein p37 LSM PF01423.17 KFX89014.1 - 1.6e-13 49.9 0.0 2.8e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 LSM domain ARID PF01388.16 KFX89026.1 - 1.2e-19 69.9 0.1 2.2e-19 69.0 0.1 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PH PF00169.24 KFX89027.1 - 0.0014 18.7 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 PH domain Apolipoprotein PF01442.13 KFX89027.1 - 0.034 13.6 0.6 0.063 12.7 0.4 1.5 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain F-actin_cap_A PF01267.12 KFX89028.1 - 9.7e-93 310.1 0.0 1.2e-92 309.7 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Cyt-b5 PF00173.23 KFX89028.1 - 1.5e-23 82.3 0.4 4.2e-23 80.9 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain VHS PF00790.14 KFX89029.1 - 9.7e-33 112.7 1.6 1.7e-32 111.9 1.1 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 KFX89029.1 - 6.2e-16 57.5 0.0 1.2e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFX89029.1 - 1.2e-15 56.7 0.1 2.3e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFX89029.1 - 3e-14 52.2 0.0 5.4e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 KFX89029.1 - 0.036 13.6 0.7 0.089 12.4 0.5 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif LRR_6 PF13516.1 KFX89030.1 - 6.9e-12 44.1 11.7 0.011 15.6 0.0 8.5 9 0 0 9 9 9 2 Leucine Rich repeat F-box-like PF12937.2 KFX89030.1 - 4e-09 36.0 1.8 1.3e-08 34.4 0.6 2.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KFX89030.1 - 1.4e-06 27.7 0.8 5.9e-06 25.7 0.6 2.2 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 KFX89030.1 - 2.9e-06 26.7 9.2 0.017 14.7 0.2 6.0 3 3 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFX89030.1 - 0.00075 19.1 18.0 0.22 11.6 0.1 8.4 10 2 0 10 10 10 2 Leucine Rich Repeat LRR_8 PF13855.1 KFX89030.1 - 0.025 14.3 12.0 0.31 10.8 0.2 5.4 5 2 1 6 6 6 0 Leucine rich repeat LRR_7 PF13504.1 KFX89030.1 - 0.093 12.9 18.1 14 6.4 0.1 8.8 10 1 1 11 11 11 0 Leucine rich repeat Ribosomal_L3 PF00297.17 KFX89031.1 - 2.8e-119 397.3 7.4 3.4e-119 397.0 5.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 IMS PF00817.15 KFX89033.1 - 6.4e-39 133.1 0.0 9.6e-39 132.5 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KFX89033.1 - 1e-09 38.3 0.3 4.7e-09 36.2 0.1 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KFX89033.1 - 0.012 15.6 0.0 0.034 14.2 0.0 1.8 1 0 0 1 1 1 0 IMS family HHH motif G_glu_transpept PF01019.16 KFX89034.1 - 1.4e-155 518.6 0.1 1.6e-155 518.4 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase PI-PLC-Y PF00387.14 KFX89039.1 - 1.3e-39 134.7 0.0 2e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 KFX89039.1 - 9.8e-09 34.9 0.0 1.3e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 C2 domain DUF3747 PF12565.3 KFX89045.1 - 0.07 12.1 0.5 7.4 5.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3747) UCH PF00443.24 KFX89047.1 - 3.7e-75 252.4 0.0 1.3e-74 250.6 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFX89047.1 - 1.1e-13 51.3 0.0 5.2e-07 29.3 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KFX89047.1 - 1.3e-07 31.9 0.0 3.2e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 DUSP domain TFIIF_alpha PF05793.7 KFX89050.1 - 0.74 8.1 4.1 0.88 7.8 2.8 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-CCHC PF00098.18 KFX89051.1 - 2.8e-07 30.1 1.9 5.4e-07 29.2 1.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Nop53 PF07767.6 KFX89051.1 - 0.0013 17.8 7.2 0.0013 17.8 5.0 1.8 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) Cwf_Cwc_15 PF04889.7 KFX89051.1 - 0.016 14.9 19.5 0.03 14.0 13.4 1.5 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-CCHC_2 PF13696.1 KFX89051.1 - 0.027 13.9 0.8 0.055 12.9 0.5 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 KFX89051.1 - 0.035 13.8 0.2 0.067 12.9 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle CDC45 PF02724.9 KFX89051.1 - 0.15 10.1 10.0 0.21 9.5 6.9 1.2 1 0 0 1 1 1 0 CDC45-like protein MPP6 PF10175.4 KFX89051.1 - 0.68 10.3 12.7 0.95 9.8 0.0 3.4 4 0 0 4 4 4 0 M-phase phosphoprotein 6 zf-CHCC PF10276.4 KFX89052.1 - 2.6e-16 59.1 1.9 4.5e-16 58.4 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger domain I_LWEQ PF01608.12 KFX89052.1 - 0.2 11.5 1.8 0.28 11.0 1.3 1.2 1 0 0 1 1 1 0 I/LWEQ domain Glyco_transf_21 PF13506.1 KFX89053.1 - 0.00046 19.5 0.0 0.0024 17.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 KFX89053.1 - 0.012 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Toxin_61 PF15538.1 KFX89053.1 - 0.013 15.5 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 Putative toxin 61 KASH PF10541.4 KFX89053.1 - 0.21 11.4 0.7 0.49 10.2 0.0 1.9 2 0 0 2 2 2 0 Nuclear envelope localisation domain Lactamase_B_2 PF12706.2 KFX89055.1 - 5.1e-38 130.5 0.0 6.3e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KFX89055.1 - 5.1e-11 42.5 0.0 1.1e-10 41.5 0.0 1.6 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KFX89055.1 - 0.0017 18.0 0.5 0.0048 16.5 0.3 1.9 1 1 1 2 2 2 1 Metallo-beta-lactamase superfamily Abhydrolase_3 PF07859.8 KFX89056.1 - 6.1e-12 45.5 0.0 8.4e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold APH PF01636.18 KFX89060.1 - 6.3e-17 62.1 0.2 1.3e-16 61.0 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX89060.1 - 0.00018 21.1 0.0 0.0012 18.5 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.15 KFX89060.1 - 0.0029 16.8 0.0 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 KFX89060.1 - 0.037 13.3 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Toxin_5 PF05294.8 KFX89061.1 - 0.38 10.9 2.9 0.66 10.2 2.0 1.3 1 0 0 1 1 1 0 Scorpion short toxin LSR PF05624.9 KFX89063.1 - 0.1 12.3 0.6 0.1 12.3 0.4 1.8 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) Spc97_Spc98 PF04130.8 KFX89064.1 - 3.2e-58 197.3 0.2 5.2e-58 196.7 0.1 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 KFX89064.1 - 8.9e-05 20.8 0.0 0.00024 19.4 0.0 1.7 1 1 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Glyco_transf_15 PF01793.11 KFX89065.1 - 3.9e-133 443.4 8.1 5.7e-133 442.9 5.6 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Aminotran_1_2 PF00155.16 KFX89065.1 - 7.3e-14 51.4 0.0 2.8e-13 49.5 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Tannase PF07519.6 KFX89065.1 - 0.0042 15.8 0.0 0.0078 14.9 0.0 1.3 1 0 0 1 1 1 1 Tannase and feruloyl esterase MTHFR PF02219.12 KFX89066.1 - 3.4e-103 344.6 0.0 4.8e-103 344.1 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Plasmid_RAQPRD PF09686.5 KFX89068.1 - 0.018 15.0 0.2 0.067 13.2 0.0 2.1 1 1 1 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Ank PF00023.25 KFX89069.1 - 0.065 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeat Hira PF07569.6 KFX89076.1 - 7.7e-70 234.5 0.0 2.1e-69 233.1 0.0 1.8 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 KFX89076.1 - 1.6e-42 141.8 20.9 3.2e-07 29.9 0.0 8.7 8 0 0 8 8 8 7 WD domain, G-beta repeat HIRA_B PF09453.5 KFX89076.1 - 1.5e-10 40.3 1.1 3.6e-10 39.1 0.8 1.7 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 KFX89076.1 - 1.2e-05 24.8 0.7 3.9 7.2 0.0 4.8 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 KFX89076.1 - 0.0018 18.0 0.1 4.6 6.8 0.0 3.8 5 0 0 5 5 5 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KFX89076.1 - 0.0051 14.7 0.4 0.086 10.6 0.0 2.3 3 0 0 3 3 3 1 IKI3 family CoA_binding PF02629.14 KFX89078.1 - 1.8e-19 70.0 0.0 9.6e-19 67.6 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain CoA_binding_2 PF13380.1 KFX89078.1 - 0.053 13.6 0.0 0.087 12.9 0.0 1.2 1 0 0 1 1 1 0 CoA binding domain ATP-grasp_2 PF08442.5 KFX89079.1 - 1e-06 28.3 0.0 1.6e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Glyco_hydro_72 PF03198.9 KFX89080.1 - 1.7e-111 372.2 0.1 2.1e-111 371.9 0.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 KFX89080.1 - 0.00015 20.8 0.0 0.00025 20.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 KFX89080.1 - 0.072 12.2 0.3 3.1 6.9 0.2 2.2 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Piwi PF02171.12 KFX89093.1 - 3.5e-44 150.9 0.0 5.3e-44 150.4 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KFX89093.1 - 3e-09 36.2 0.0 5.7e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KFX89093.1 - 1.9e-08 33.5 0.0 5.2e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) ACBP PF00887.14 KFX89094.1 - 1.8e-16 59.5 0.5 2.4e-16 59.1 0.3 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein Tyr-DNA_phospho PF06087.7 KFX89095.1 - 8.4e-126 420.1 0.0 9.9e-126 419.9 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 KFX89095.1 - 0.0071 16.0 0.0 0.15 11.8 0.0 2.2 2 0 0 2 2 2 1 PLD-like domain PLDc PF00614.17 KFX89095.1 - 0.14 11.9 0.1 5 7.0 0.3 2.6 2 0 0 2 2 2 0 Phospholipase D Active site motif Atg8 PF02991.11 KFX89099.1 - 5.3e-51 170.9 0.2 6.2e-51 170.7 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KFX89099.1 - 3.6e-06 27.0 0.0 4.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.13 KFX89100.1 - 2.6e-135 449.7 0.2 3.1e-135 449.4 0.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase adh_short PF00106.20 KFX89108.1 - 1.7e-19 70.3 0.1 3.9e-19 69.1 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KFX89108.1 - 3.2e-06 27.2 0.0 5.8e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KFX89108.1 - 0.0037 16.9 0.1 0.0098 15.5 0.1 1.8 1 1 0 1 1 1 1 KR domain 4HBT PF03061.17 KFX89108.1 - 0.024 14.7 0.2 0.22 11.6 0.0 2.4 2 0 0 2 2 2 0 Thioesterase superfamily NAD_binding_2 PF03446.10 KFX89108.1 - 0.037 13.8 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase HHH_5 PF14520.1 KFX89108.1 - 0.095 12.8 0.2 0.21 11.8 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Peptidase_S8 PF00082.17 KFX89110.1 - 3.4e-50 170.7 23.6 9e-26 90.6 6.3 2.1 1 1 1 2 2 2 2 Subtilase family Inhibitor_I9 PF05922.11 KFX89110.1 - 1.7e-10 41.3 0.1 3.4e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Pkinase PF00069.20 KFX89117.1 - 9.4e-60 201.9 0.0 1.1e-59 201.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX89117.1 - 2.2e-36 125.2 0.0 3.5e-36 124.5 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX89117.1 - 2.4e-08 33.2 0.0 3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KFX89117.1 - 0.084 11.6 0.1 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Abhydrolase_6 PF12697.2 KFX89118.1 - 2.7e-17 63.4 0.1 8.6e-17 61.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX89118.1 - 3.8e-05 23.4 0.0 4.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX89118.1 - 0.0013 18.2 0.0 0.0038 16.8 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Glyoxalase PF00903.20 KFX89121.1 - 1.5e-22 79.8 0.2 5.1e-15 55.5 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KFX89121.1 - 2.5e-13 50.0 0.1 7.9e-06 25.8 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KFX89121.1 - 6.8e-11 42.7 0.0 2.6e-05 24.7 0.0 2.7 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 KFX89121.1 - 1.4e-07 31.4 0.1 3.7e-06 26.9 0.1 2.7 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 KFX89121.1 - 9.2e-07 28.9 0.2 0.047 13.5 0.1 3.5 2 2 0 2 2 2 2 Glyoxalase-like domain polyprenyl_synt PF00348.12 KFX89132.1 - 5e-32 110.7 0.0 8.9e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 KFX89132.1 - 1.3e-06 27.9 0.0 0.00049 19.4 0.0 2.4 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain Endonuc-HincII PF09226.6 KFX89132.1 - 0.062 12.6 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease HincII DUF3650 PF12368.3 KFX89132.1 - 0.24 10.9 0.6 0.62 9.6 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) ABC_tran PF00005.22 KFX89133.1 - 2e-28 99.3 0.1 3.3e-28 98.6 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFX89133.1 - 3.2e-07 30.6 0.4 0.00023 21.2 0.3 2.3 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFX89133.1 - 3.3e-05 23.1 0.5 5.7e-05 22.3 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ArgK PF03308.11 KFX89133.1 - 0.00056 18.7 0.1 0.0011 17.8 0.1 1.4 1 0 0 1 1 1 1 ArgK protein AAA_17 PF13207.1 KFX89133.1 - 0.003 18.3 0.0 0.0055 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFX89133.1 - 0.007 16.6 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFX89133.1 - 0.0085 15.5 0.8 0.025 14.0 0.5 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KFX89133.1 - 0.0098 15.8 0.1 0.016 15.1 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.10 KFX89133.1 - 0.036 12.7 0.0 0.053 12.2 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein ABC2_membrane PF01061.19 KFX89133.1 - 0.046 12.8 0.1 0.075 12.1 0.1 1.3 1 0 0 1 1 1 0 ABC-2 type transporter MMR_HSR1 PF01926.18 KFX89133.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_10 PF12846.2 KFX89133.1 - 0.053 12.9 0.1 0.078 12.3 0.1 1.2 1 0 0 1 1 1 0 AAA-like domain SbcCD_C PF13558.1 KFX89133.1 - 0.098 12.5 0.1 0.28 11.1 0.1 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 KFX89133.1 - 0.098 11.8 1.4 2.2 7.4 0.2 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KFX89133.1 - 0.11 12.5 0.3 0.36 10.9 0.2 1.9 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 KFX89133.1 - 0.12 11.2 0.2 0.18 10.6 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 KFX89133.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 KFX89133.1 - 0.18 11.6 0.2 0.33 10.8 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFX89133.1 - 0.21 10.9 0.3 5.7 6.2 0.2 2.2 2 0 0 2 2 2 0 AAA domain GPI-anchored PF10342.4 KFX89141.1 - 1.4e-12 47.9 0.1 1.4e-12 47.9 0.1 2.4 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family WD40 PF00400.27 KFX89141.1 - 2.9e-06 26.9 0.1 0.012 15.5 0.2 3.4 2 1 0 2 2 2 2 WD domain, G-beta repeat Peptidase_C14 PF00656.17 KFX89142.1 - 4.8e-58 196.7 0.0 5.7e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KFX89142.1 - 0.023 14.5 0.2 0.79 9.5 0.0 2.6 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain Epimerase PF01370.16 KFX89150.1 - 8.5e-11 41.7 0.0 6.5e-08 32.3 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFX89150.1 - 2.4e-06 26.4 0.2 6.1e-06 25.1 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFX89150.1 - 4.3e-05 23.5 0.3 7.1e-05 22.8 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFX89150.1 - 0.00055 19.2 0.3 0.00085 18.6 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KFX89150.1 - 0.0018 18.2 0.2 0.0027 17.6 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX89150.1 - 0.0019 17.9 0.2 0.0032 17.1 0.1 1.3 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 KFX89150.1 - 0.002 18.1 0.3 0.0042 17.0 0.2 1.5 1 0 0 1 1 1 1 TrkA-N domain RmlD_sub_bind PF04321.12 KFX89150.1 - 0.0027 16.6 0.2 0.21 10.4 0.1 2.3 2 1 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KFX89150.1 - 0.017 14.0 1.3 0.13 11.1 0.5 2.3 2 1 0 2 2 2 0 Male sterility protein Polysacc_synt_2 PF02719.10 KFX89150.1 - 0.045 12.6 0.2 0.072 11.9 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Rhodanese PF00581.15 KFX89150.1 - 0.13 12.6 0.0 0.42 10.9 0.0 1.8 2 1 1 3 3 3 0 Rhodanese-like domain ChaC PF04752.7 KFX89151.1 - 2.7e-57 193.5 0.0 3.2e-57 193.3 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein CytochromB561_N PF09786.4 KFX89153.1 - 2.1 6.7 9.7 2.3 6.5 6.7 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal NAD_binding_8 PF13450.1 KFX89155.1 - 1.5e-15 56.9 0.0 6.4e-15 54.9 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFX89155.1 - 1.1e-06 27.8 0.0 5.5e-05 22.2 0.0 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFX89155.1 - 6.8e-06 25.1 0.1 0.00048 19.0 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KFX89155.1 - 0.00034 20.5 0.1 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX89155.1 - 0.00042 20.1 0.0 0.0082 15.9 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KFX89155.1 - 0.00087 19.6 0.2 0.95 9.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KFX89155.1 - 0.00089 18.4 0.0 0.67 8.9 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase HI0933_like PF03486.9 KFX89155.1 - 0.0014 17.1 0.1 0.38 9.1 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Mqo PF06039.10 KFX89155.1 - 0.017 13.3 0.0 0.026 12.7 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Trp_halogenase PF04820.9 KFX89155.1 - 0.038 12.6 0.0 0.059 11.9 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 KFX89155.1 - 0.059 13.4 0.0 4.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFX89155.1 - 0.13 11.1 0.2 0.21 10.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Glyoxalase_2 PF12681.2 KFX89157.1 - 1.2e-07 32.2 0.1 1.5e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KFX89157.1 - 0.00042 20.2 0.3 0.0011 18.8 0.2 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Aldose_epim PF01263.15 KFX89158.1 - 1.1e-50 172.5 1.0 1.2e-50 172.3 0.7 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase RVT_2 PF07727.9 KFX89162.1 - 4.2e-78 261.7 0.0 8.1e-78 260.7 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 KFX89162.1 - 6.1e-19 68.2 0.2 3.7e-18 65.7 0.1 2.4 2 0 0 2 2 2 1 Integrase core domain UBN2 PF14223.1 KFX89162.1 - 2.2e-10 40.3 0.1 4.9e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.1 KFX89162.1 - 1.2e-09 37.6 0.1 1.5e-08 34.1 0.0 3.0 2 0 0 2 2 2 1 GAG-pre-integrase domain UBN2_2 PF14227.1 KFX89162.1 - 1.6e-09 37.3 0.2 4.1e-09 36.0 0.2 1.7 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Zn_clus PF00172.13 KFX89162.1 - 0.02 14.7 85.5 0.024 14.5 6.9 6.1 4 2 0 5 5 5 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Exo70 PF03081.10 KFX89169.1 - 2e-65 221.0 0.0 5.5e-65 219.5 0.0 1.6 2 0 0 2 2 2 1 Exo70 exocyst complex subunit DUF4208 PF13907.1 KFX89169.1 - 0.019 15.1 2.7 1.1 9.5 0.0 3.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4208) zf-CCCH PF00642.19 KFX89173.1 - 9e-13 47.5 1.5 3.2e-06 26.6 0.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TFIIF_beta PF02270.10 KFX89174.1 - 8e-79 265.2 0.1 9.4e-79 265.0 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit DDE_Tnp_IS66_C PF13817.1 KFX89174.1 - 0.036 14.0 0.0 0.093 12.7 0.0 1.7 1 0 0 1 1 1 0 IS66 C-terminal element CBF PF03914.12 KFX89175.1 - 2.9e-46 156.9 1.0 9.2e-46 155.2 0.0 2.3 3 0 0 3 3 3 1 CBF/Mak21 family Mt_ATP-synt_B PF05405.9 KFX89176.1 - 6.8e-50 168.7 4.9 8.7e-50 168.3 3.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) tRNA_anti-codon PF01336.20 KFX89176.1 - 0.0012 18.5 0.1 0.0023 17.7 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Rep_trans PF02486.14 KFX89176.1 - 0.097 12.1 1.1 0.17 11.3 0.8 1.4 1 1 0 1 1 1 0 Replication initiation factor YbjQ_1 PF01906.12 KFX89177.1 - 1.3e-31 109.1 0.4 1.7e-31 108.7 0.3 1.2 1 0 0 1 1 1 1 Putative heavy-metal-binding Hexapep PF00132.19 KFX89185.1 - 6.4e-08 31.7 10.0 0.0051 16.2 0.3 3.9 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KFX89185.1 - 0.13 11.8 8.3 0.18 11.4 0.3 3.7 4 1 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase MFS_1 PF07690.11 KFX89194.1 - 1.3e-09 37.3 12.9 1.5e-09 37.0 8.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFX89194.1 - 0.0056 15.1 3.1 0.008 14.6 2.2 1.3 1 1 0 1 1 1 1 MFS/sugar transport protein NfeD PF01957.13 KFX89194.1 - 0.31 11.1 4.6 0.25 11.4 0.7 2.1 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Cupin_8 PF13621.1 KFX89195.1 - 2.5e-35 122.1 0.0 4.4e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.9 KFX89195.1 - 1.5e-23 83.2 0.0 2.2e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.1 KFX89195.1 - 3.6e-14 52.2 19.1 8.3e-06 25.4 0.0 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 KFX89195.1 - 2.2e-07 30.6 0.2 0.00058 19.7 0.0 3.5 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 KFX89195.1 - 4.7e-07 29.7 4.4 0.0037 17.3 0.0 4.8 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KFX89195.1 - 7.8e-06 25.8 4.3 0.0088 16.1 0.0 3.7 3 1 1 4 4 4 2 Kelch motif Cupin_4 PF08007.7 KFX89195.1 - 2.2e-05 23.8 0.0 4.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_1 PF01344.20 KFX89195.1 - 0.0001 21.7 0.0 0.78 9.3 0.0 4.3 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 KFX89195.1 - 0.0013 18.4 4.6 0.22 11.3 0.1 3.9 4 0 0 4 4 4 2 Kelch motif WD40 PF00400.27 KFX89196.1 - 2.1e-06 27.3 0.2 0.0027 17.5 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Citrate_synt PF00285.16 KFX89197.1 - 9.9e-08 31.0 0.0 9.7e-07 27.8 0.0 1.9 1 1 0 1 1 1 1 Citrate synthase Mg_trans_NIPA PF05653.9 KFX89201.1 - 1.6e-71 240.7 26.3 3.8e-69 232.9 18.2 2.0 1 1 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KFX89201.1 - 3.2e-06 27.2 7.7 3.2e-06 27.2 5.3 3.1 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KFX89201.1 - 1.4e-05 25.0 6.9 1.4e-05 25.0 4.8 3.2 3 1 0 3 3 3 1 EamA-like transporter family Neurensin PF14927.1 KFX89201.1 - 0.92 8.8 4.9 1.8 7.9 1.0 2.8 3 0 0 3 3 3 0 Neurensin Asp PF00026.18 KFX89203.1 - 3.5e-39 134.9 6.0 3.8e-38 131.5 4.2 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KFX89203.1 - 0.00086 19.7 3.4 0.011 16.1 0.4 3.2 2 2 1 3 3 3 1 Aspartyl protease TAXi_N PF14543.1 KFX89203.1 - 0.0066 16.4 4.0 0.11 12.4 0.4 3.2 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 KFX89203.1 - 0.072 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease HET PF06985.6 KFX89208.1 - 1.6e-20 73.6 0.0 2.4e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Clusterin PF01093.12 KFX89208.1 - 0.1 11.3 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Clusterin zf-DHHC PF01529.15 KFX89211.1 - 8.5e-27 93.6 2.6 8.5e-27 93.6 1.8 2.2 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF503 PF04456.7 KFX89212.1 - 0.07 12.7 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF503) GspL_C PF12693.2 KFX89213.1 - 0.37 10.5 3.6 0.63 9.8 2.5 1.3 1 0 0 1 1 1 0 GspL periplasmic domain Acetyltransf_10 PF13673.1 KFX89214.1 - 6.5e-11 42.3 0.1 1.7e-07 31.3 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX89214.1 - 7.8e-11 41.8 1.4 2.8e-10 40.0 1.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFX89214.1 - 1.2e-08 34.9 0.0 3e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFX89214.1 - 0.00014 21.7 0.0 0.031 14.1 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFX89214.1 - 0.00026 20.8 0.0 0.00041 20.1 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 KFX89214.1 - 0.016 15.1 0.0 0.085 12.7 0.0 2.2 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DHquinase_I PF01487.10 KFX89215.1 - 3.1e-25 89.1 0.0 4.5e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 KFX89215.1 - 1.1e-13 51.0 0.1 2.2e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KFX89215.1 - 8.1e-13 48.6 0.0 1.6e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 KFX89215.1 - 0.071 12.9 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 ThiF family Saccharop_dh PF03435.13 KFX89215.1 - 0.17 10.8 0.0 0.24 10.3 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Pal1 PF08316.6 KFX89227.1 - 7.4e-48 162.5 0.5 1.5e-47 161.5 0.4 1.5 1 0 0 1 1 1 1 Pal1 cell morphology protein RTA1 PF04479.8 KFX89231.1 - 6.6e-16 58.4 3.5 9.2e-16 58.0 1.6 1.7 1 1 0 1 1 1 1 RTA1 like protein PAP2_C PF14360.1 KFX89231.1 - 0.067 13.4 2.5 0.27 11.5 1.7 2.1 1 0 0 1 1 1 0 PAP2 superfamily C-terminal Arginase PF00491.16 KFX89232.1 - 8.6e-73 245.0 1.0 9.8e-73 244.8 0.7 1.0 1 0 0 1 1 1 1 Arginase family Kdo PF06293.9 KFX89248.1 - 3e-10 39.5 0.0 5.7e-10 38.6 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFX89248.1 - 1.3e-09 38.1 0.2 0.00016 21.5 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 KFX89248.1 - 4.6e-09 35.8 0.0 5.6e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX89248.1 - 6.8e-05 22.0 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KFX89248.1 - 0.00049 19.4 0.0 0.0014 18.0 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 KFX89248.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Aldo_ket_red PF00248.16 KFX89249.1 - 2.7e-10 39.5 0.0 3.6e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.15 KFX89250.1 - 1.2e-52 177.4 1.3 1.4e-52 177.1 0.9 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Maf1 PF09174.5 KFX89251.1 - 1.2e-56 191.3 0.0 1.7e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator Cwf_Cwc_15 PF04889.7 KFX89251.1 - 0.44 10.2 9.7 0.59 9.8 6.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ribosomal_L7Ae PF01248.21 KFX89252.1 - 4.8e-26 90.0 0.1 5.7e-26 89.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 KFX89252.1 - 0.00027 20.8 0.0 0.00034 20.4 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 KFX89252.1 - 0.06 13.1 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain ATP-synt_C PF00137.16 KFX89253.1 - 8.1e-32 108.9 29.0 7.9e-19 67.3 8.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.3 KFX89253.1 - 6 6.5 10.1 0.64 9.6 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) CMD PF02627.15 KFX89254.1 - 3.9e-10 39.4 0.2 3.2e-08 33.3 0.0 2.5 3 0 0 3 3 3 2 Carboxymuconolactone decarboxylase family bZIP_1 PF00170.16 KFX89256.1 - 2.9e-08 33.5 8.1 5.3e-08 32.7 5.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFX89256.1 - 0.0054 16.5 7.8 0.0054 16.5 5.4 1.6 2 0 0 2 2 2 1 Basic region leucine zipper V_ATPase_I PF01496.14 KFX89256.1 - 0.012 13.5 0.5 0.013 13.3 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.6 KFX89256.1 - 0.023 14.5 3.9 0.03 14.1 2.7 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) GAS PF13851.1 KFX89256.1 - 0.049 12.8 4.0 0.071 12.3 2.8 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding bZIP_Maf PF03131.12 KFX89256.1 - 0.23 11.7 10.2 0.49 10.7 7.0 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Tom37_C PF11801.3 KFX89256.1 - 0.3 10.9 8.4 0.1 12.4 3.5 1.6 1 1 1 2 2 2 0 Tom37 C-terminal domain APG6 PF04111.7 KFX89256.1 - 0.31 10.0 5.0 0.44 9.5 3.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 KFX89256.1 - 0.33 10.5 6.8 0.52 9.8 4.7 1.2 1 0 0 1 1 1 0 IncA protein HAUS6_N PF14661.1 KFX89256.1 - 0.72 9.1 4.5 0.9 8.8 3.2 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF972 PF06156.8 KFX89256.1 - 0.72 10.2 3.7 1 9.7 2.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) M PF02370.11 KFX89256.1 - 3 8.5 6.7 2.9 8.5 0.3 2.9 2 1 0 2 2 2 0 M protein repeat Med9 PF07544.8 KFX89257.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 AAA_11 PF13086.1 KFX89259.1 - 3.3e-60 203.5 0.1 4.7e-60 203.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 KFX89259.1 - 7.3e-56 188.7 0.0 1.2e-55 188.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFX89259.1 - 2.5e-13 49.5 0.0 2.6e-12 46.2 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KFX89259.1 - 3e-10 39.9 0.0 1.2e-08 34.7 0.0 2.6 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KFX89259.1 - 2.9e-07 30.4 0.0 1e-06 28.6 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KFX89259.1 - 1.2e-05 24.4 0.2 0.00016 20.7 0.1 2.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 KFX89259.1 - 4.4e-05 23.1 0.0 0.24 10.8 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 KFX89259.1 - 0.00011 21.6 0.5 0.0015 17.9 0.0 2.4 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 KFX89259.1 - 0.00061 19.9 0.1 0.0069 16.5 0.1 2.4 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 KFX89259.1 - 0.0036 16.9 0.0 0.11 12.1 0.0 2.4 1 1 0 1 1 1 1 Helicase AAA_25 PF13481.1 KFX89259.1 - 0.0044 16.4 0.0 0.013 14.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 KFX89259.1 - 0.0044 16.5 0.0 0.011 15.2 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.13 KFX89259.1 - 0.0045 16.4 0.0 0.048 13.1 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family PhoH PF02562.11 KFX89259.1 - 0.0053 16.0 0.0 0.099 11.8 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.12 KFX89259.1 - 0.0076 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein UvrD_C PF13361.1 KFX89259.1 - 0.0084 15.6 0.0 13 5.1 0.0 3.2 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 KFX89259.1 - 0.0088 16.0 0.1 0.019 14.9 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 KFX89259.1 - 0.014 14.2 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 KFX89259.1 - 0.02 15.0 1.3 0.076 13.2 0.0 2.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Flavi_DEAD PF07652.9 KFX89259.1 - 0.022 14.4 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain 4HB_MCP_1 PF12729.2 KFX89259.1 - 0.09 12.1 0.2 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction PIF1 PF05970.9 KFX89259.1 - 0.094 11.6 0.0 4.2 6.2 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Mg_chelatase PF01078.16 KFX89259.1 - 0.095 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.22 KFX89259.1 - 0.11 12.8 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 KFX89259.1 - 0.21 12.4 1.0 0.61 10.9 0.5 2.2 1 1 0 1 1 1 0 AAA domain adh_short_C2 PF13561.1 KFX89261.1 - 3.1e-10 40.2 0.0 5.7e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFX89261.1 - 8.4e-09 35.5 0.4 8.3e-08 32.3 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase DUF1776 PF08643.5 KFX89261.1 - 0.067 12.3 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Nucleoporin_FG PF13634.1 KFX89264.1 - 1.9e-17 63.4 125.1 6.6e-07 29.5 23.2 4.2 1 1 3 4 4 4 4 Nucleoporin FG repeat region AA_permease PF00324.16 KFX89278.1 - 1.1e-33 116.3 5.3 1.2e-33 116.1 3.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFX89278.1 - 1.5e-08 33.6 5.8 2e-08 33.2 4.0 1.3 1 1 0 1 1 1 1 Amino acid permease bPH_6 PF10756.4 KFX89278.1 - 0.22 11.4 2.4 0.89 9.4 0.1 2.2 2 0 0 2 2 2 0 Bacterial PH domain Pneumo_att_G PF05539.6 KFX89308.1 - 5.9 6.1 8.3 6.4 6.0 5.7 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF605 PF04652.11 KFX89308.1 - 7.3 5.8 14.3 8.6 5.6 9.9 1.1 1 0 0 1 1 1 0 Vta1 like TRAM_LAG1_CLN8 PF03798.11 KFX89309.1 - 1.8e-34 119.0 14.5 1.8e-34 119.0 10.1 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KFX89309.1 - 2.1e-19 68.7 0.0 4.4e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 TRAM1-like protein DUF4637 PF15470.1 KFX89309.1 - 1.4 8.4 6.9 6.6 6.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) SAM_2 PF07647.12 KFX89310.1 - 4.7e-14 51.9 0.0 1.1e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 KFX89310.1 - 4.7e-13 49.4 0.0 1.1e-12 48.2 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.25 KFX89310.1 - 3.4e-10 39.9 0.0 5.6e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) C2 PF00168.25 KFX89312.1 - 1.5e-08 34.3 0.0 2.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF4175 PF13779.1 KFX89312.1 - 8.6 3.9 8.7 11 3.5 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Aldo_ket_red PF00248.16 KFX89318.1 - 2.8e-41 141.1 0.0 3.4e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family rve_2 PF13333.1 KFX89318.1 - 0.084 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Aldo_ket_red PF00248.16 KFX89319.1 - 4.2e-25 88.1 0.0 5.1e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CoA_transf_3 PF02515.12 KFX89321.1 - 1.2e-58 197.5 0.3 2.8e-58 196.3 0.1 1.7 2 0 0 2 2 2 1 CoA-transferase family III adh_short PF00106.20 KFX89325.1 - 3.9e-21 75.6 0.1 5.1e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX89325.1 - 1.1e-11 44.7 0.0 1.4e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFX89325.1 - 0.00062 19.6 0.0 0.00072 19.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 KFX89325.1 - 0.00073 18.5 0.0 0.00087 18.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KFX89325.1 - 0.0013 18.8 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 KFX89325.1 - 0.012 15.0 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ALAD PF00490.16 KFX89326.1 - 8.8e-117 389.5 0.0 1.1e-116 389.3 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase PAPA-1 PF04795.7 KFX89327.1 - 1.7e-05 25.4 10.8 1.7e-05 25.4 7.5 4.1 4 1 0 4 4 4 1 PAPA-1-like conserved region NUDIX PF00293.23 KFX89328.1 - 2.8e-08 33.4 0.0 6.5e-08 32.2 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain PGA2 PF07543.7 KFX89335.1 - 9.9e-35 119.3 3.3 1.3e-34 119.0 2.3 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 DUF2380 PF09533.5 KFX89336.1 - 0.063 12.6 0.8 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 Predicted lipoprotein of unknown function (DUF2380) ZZ PF00569.12 KFX89336.1 - 0.54 9.8 3.9 3 7.4 0.1 3.0 3 0 0 3 3 3 0 Zinc finger, ZZ type SpoIIE PF07228.7 KFX89338.1 - 1.1e-05 25.2 0.0 3e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 KFX89338.1 - 2.3e-05 23.9 0.0 0.0079 15.6 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 KFX89338.1 - 5.3e-05 22.7 0.1 7.9e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C Fcf1 PF04900.7 KFX89339.1 - 1.8e-29 101.7 0.0 2.9e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 Fcf1 CTP_transf_2 PF01467.21 KFX89345.1 - 5.7e-09 36.2 0.0 6.3e-09 36.0 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase AraC_N PF06719.8 KFX89346.1 - 0.11 11.7 0.0 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 AraC-type transcriptional regulator N-terminus DUF605 PF04652.11 KFX89346.1 - 2 7.7 7.2 2.8 7.2 5.0 1.2 1 0 0 1 1 1 0 Vta1 like Extensin_2 PF04554.8 KFX89347.1 - 0.062 13.1 7.3 42 4.1 5.0 3.3 1 1 0 1 1 1 0 Extensin-like region Molydop_binding PF01568.16 KFX89347.1 - 0.074 12.8 0.4 0.97 9.2 0.1 2.1 1 1 0 2 2 2 0 Molydopterin dinucleotide binding domain CoA_binding_2 PF13380.1 KFX89347.1 - 0.17 12.0 1.5 20 5.3 0.2 2.9 1 1 1 2 2 2 0 CoA binding domain PTCRA PF15028.1 KFX89347.1 - 0.47 10.0 1.7 0.96 9.0 0.5 1.8 1 1 1 2 2 2 0 Pre-T-cell antigen receptor DUF2025 PF09634.5 KFX89347.1 - 0.72 9.6 3.9 12 5.7 0.0 3.8 1 1 4 5 5 5 0 Protein of unknown function (DUF2025) GalKase_gal_bdg PF10509.4 KFX89347.1 - 4.9 6.5 6.8 96 2.3 0.0 4.2 3 2 2 5 5 5 0 Galactokinase galactose-binding signature PXPV PF12778.2 KFX89347.1 - 10 5.9 32.8 4.5 7.0 0.5 5.0 4 2 0 4 4 4 0 PXPV repeat (3 copies) Vps54 PF07928.7 KFX89348.1 - 2.1e-42 144.4 0.0 4.9e-42 143.2 0.0 1.7 1 0 0 1 1 1 1 Vps54-like protein DUF2450 PF10475.4 KFX89348.1 - 2e-05 23.6 2.0 3.5e-05 22.8 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Sec8_exocyst PF04048.9 KFX89348.1 - 0.053 13.1 0.6 0.37 10.4 0.1 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Phage_prot_Gp6 PF05133.9 KFX89348.1 - 0.33 9.4 4.4 0.089 11.3 0.7 1.7 2 0 0 2 2 2 0 Phage portal protein, SPP1 Gp6-like MCM PF00493.18 KFX89349.1 - 8.6e-144 478.3 0.2 1.1e-143 477.9 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KFX89349.1 - 2.4e-20 73.2 0.1 7.1e-20 71.7 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFX89349.1 - 9.6e-08 31.4 0.1 5.8e-05 22.3 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KFX89349.1 - 9.2e-05 22.1 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KFX89349.1 - 0.00056 19.5 0.1 0.0021 17.6 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KFX89349.1 - 0.0035 16.8 0.1 2.5 7.5 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA PF00004.24 KFX89349.1 - 0.042 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 KFX89349.1 - 0.047 14.0 0.3 0.16 12.3 0.1 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF1016 PF06250.6 KFX89349.1 - 0.1 11.5 0.2 0.19 10.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1016) MafB19-deam PF14437.1 KFX89350.1 - 0.046 13.3 0.0 0.051 13.2 0.0 1.1 1 0 0 1 1 1 0 MafB19-like deaminase DUF1048 PF06304.6 KFX89350.1 - 0.049 13.9 0.0 0.056 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) Glyco_transf_8 PF01501.15 KFX89352.1 - 1.9e-05 24.1 0.0 2.5e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Aminotran_1_2 PF00155.16 KFX89360.1 - 8.5e-37 126.9 0.0 1.4e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DXP_synthase_N PF13292.1 KFX89360.1 - 0.0075 15.2 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase RPN7 PF10602.4 KFX89361.1 - 1.8e-58 196.8 0.5 2.7e-58 196.2 0.3 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KFX89361.1 - 1.5e-13 50.9 0.0 3e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 PCI domain Prog_receptor PF02161.10 KFX89361.1 - 0.027 13.3 1.0 0.039 12.7 0.7 1.1 1 0 0 1 1 1 0 Progesterone receptor TPR_14 PF13428.1 KFX89361.1 - 0.086 13.5 0.2 1.1 10.0 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat SUR7 PF06687.7 KFX89370.1 - 1.3e-28 100.0 7.4 1.9e-28 99.5 5.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KFX89370.1 - 0.0071 16.0 12.4 0.0071 16.0 8.6 1.8 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF805 PF05656.9 KFX89370.1 - 0.097 12.5 7.6 0.14 11.9 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF805) WBP-1 PF11669.3 KFX89370.1 - 6.8 6.8 6.9 1.1 9.3 0.5 2.4 2 1 0 2 2 2 0 WW domain-binding protein 1 CmcH_NodU PF02543.10 KFX89372.1 - 3.7e-46 157.8 0.0 4.4e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Carbamoyltransferase DUF3602 PF12223.3 KFX89384.1 - 4.1e-16 59.1 9.6 1.6e-09 37.9 3.8 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) DUF4614 PF15391.1 KFX89384.1 - 0.096 12.4 3.3 0.12 12.1 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Dsh_C PF12316.3 KFX89384.1 - 1.3 9.0 15.1 1.9 8.5 10.5 1.3 1 1 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Period_C PF12114.3 KFX89384.1 - 6.5 6.3 9.9 7.8 6.0 6.9 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region GHMP_kinases_N PF00288.21 KFX89386.1 - 0.043 13.8 0.2 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 GHMP kinases N terminal domain Zn_clus PF00172.13 KFX89387.1 - 2.2e-05 24.2 10.6 2.2e-05 24.2 7.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KFX89388.1 - 4.3e-80 269.5 28.3 5e-80 269.2 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX89388.1 - 6.8e-27 94.0 26.5 6.8e-27 94.0 18.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KFX89388.1 - 0.0003 19.1 2.4 0.0003 19.1 1.7 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 KFX89389.1 - 3.5e-59 200.5 0.0 4.6e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aldose_epim PF01263.15 KFX89390.1 - 2.5e-58 197.5 0.0 3.3e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase HpcH_HpaI PF03328.9 KFX89391.1 - 4.7e-33 113.9 0.1 5.9e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Bac_luciferase PF00296.15 KFX89391.1 - 0.087 11.9 0.0 0.65 9.0 0.0 2.0 2 0 0 2 2 2 0 Luciferase-like monooxygenase adh_short PF00106.20 KFX89392.1 - 2.6e-20 72.9 2.0 3.2e-19 69.4 1.4 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX89392.1 - 6.4e-19 68.6 0.2 7.5e-19 68.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX89392.1 - 3e-06 26.9 0.2 5.1e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFX89392.1 - 0.00073 19.0 0.3 0.0039 16.6 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HORMA PF02301.13 KFX89396.1 - 1.7e-25 89.7 0.0 3e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 HORMA domain PHD PF00628.24 KFX89396.1 - 0.0082 15.8 10.8 0.017 14.8 7.5 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KFX89396.1 - 0.017 14.4 4.7 0.032 13.5 3.3 1.4 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.17 KFX89396.1 - 0.033 13.9 5.6 0.069 12.8 3.9 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Trp_halogenase PF04820.9 KFX89397.1 - 2.6e-13 49.4 0.1 1e-05 24.3 0.0 2.4 1 1 1 2 2 2 2 Tryptophan halogenase DAO PF01266.19 KFX89397.1 - 0.00016 20.7 0.0 0.00032 19.6 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.10 KFX89397.1 - 0.00038 18.7 0.0 0.00057 18.1 0.0 1.1 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) Lycopene_cycl PF05834.7 KFX89397.1 - 0.0037 16.2 0.0 0.19 10.5 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 KFX89397.1 - 0.01 14.9 0.0 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 Thi4 family NAD_binding_8 PF13450.1 KFX89397.1 - 0.011 15.6 0.0 0.033 14.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFX89397.1 - 0.074 13.4 0.0 0.62 10.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CAS_CSE1 PF03378.10 KFX89402.1 - 7.8e-21 73.8 0.0 8.5e-21 73.7 0.0 1.0 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus DUF1640 PF07798.6 KFX89403.1 - 2e-10 41.0 6.0 2e-10 41.0 4.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) AA_permease PF00324.16 KFX89417.1 - 1.3e-90 304.0 26.2 1.5e-90 303.8 18.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFX89417.1 - 5.4e-32 110.8 33.8 6.7e-32 110.5 23.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3593 PF12159.3 KFX89417.1 - 0.15 11.8 4.4 0.68 9.7 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF3593) DUF4231 PF14015.1 KFX89417.1 - 2 8.4 8.4 5.4 7.0 0.6 3.1 2 2 0 2 2 2 0 Protein of unknown function (DUF4231) Claudin_3 PF06653.6 KFX89417.1 - 6.1 6.5 13.4 0.8 9.4 0.4 3.0 3 1 0 3 3 3 0 Tight junction protein, Claudin-like Fungal_trans_2 PF11951.3 KFX89454.1 - 8.8e-08 31.1 0.9 1.4e-07 30.4 0.6 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain STE PF02200.11 KFX89456.1 - 1.1e-61 205.8 0.8 2.4e-61 204.7 0.2 1.8 2 0 0 2 2 2 1 STE like transcription factor PAT1 PF09770.4 KFX89456.1 - 1.4 7.1 28.0 2.4 6.3 19.4 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 KFX89456.1 - 3.5 7.4 17.4 5.4 6.8 12.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med16 PF11635.3 KFX89461.1 - 3.1e-95 319.7 0.0 4e-95 319.3 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 p450 PF00067.17 KFX89463.1 - 6e-82 275.6 0.0 7e-82 275.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC2_membrane_5 PF13346.1 KFX89463.1 - 0.043 13.1 0.4 0.076 12.2 0.3 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein ASL_C PF08328.6 KFX89463.1 - 0.068 13.0 0.3 0.15 11.9 0.1 1.6 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal Arf PF00025.16 KFX89465.1 - 2.6e-44 150.5 0.0 3e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFX89465.1 - 1.1e-18 67.0 0.0 1.3e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX89465.1 - 3.2e-10 40.5 0.0 5.4e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KFX89465.1 - 3.3e-08 32.9 0.0 3.8e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KFX89465.1 - 9.2e-06 24.9 0.0 1.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFX89465.1 - 1.5e-05 24.9 0.0 2.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KFX89465.1 - 8.8e-05 21.3 0.2 0.00019 20.2 0.1 1.5 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.22 KFX89465.1 - 0.0001 21.8 0.0 0.0026 17.2 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KFX89465.1 - 0.01 15.6 0.0 0.075 12.8 0.1 2.0 1 1 1 2 2 2 0 Dynamin family FeoB_N PF02421.13 KFX89465.1 - 0.013 14.7 0.1 0.071 12.3 0.0 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.4 KFX89465.1 - 0.037 13.5 0.1 0.32 10.4 0.0 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 KFX89465.1 - 0.11 12.1 0.4 0.32 10.6 0.0 1.9 2 0 0 2 2 2 0 NACHT domain RCR PF12273.3 KFX89466.1 - 1.3e-24 87.2 5.9 1.3e-24 87.2 4.1 1.4 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red Rhabdo_glycop PF00974.13 KFX89466.1 - 0.0042 15.3 0.3 0.0055 14.9 0.2 1.1 1 0 0 1 1 1 1 Rhabdovirus spike glycoprotein Acyl_transf_3 PF01757.17 KFX89466.1 - 0.032 13.0 0.3 0.04 12.7 0.2 1.1 1 0 0 1 1 1 0 Acyltransferase family WBP-1 PF11669.3 KFX89466.1 - 0.081 13.0 1.4 0.14 12.2 0.1 2.0 1 1 0 2 2 2 0 WW domain-binding protein 1 Shisa PF13908.1 KFX89466.1 - 3.5 7.7 5.4 15 5.7 3.8 2.0 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Neisseria_TspB PF05616.8 KFX89470.1 - 2.5 6.3 8.7 3.8 5.7 6.0 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Cerato-platanin PF07249.7 KFX89471.1 - 7.4e-47 158.2 0.9 8.6e-47 158.0 0.6 1.0 1 0 0 1 1 1 1 Cerato-platanin Alginate_lyase PF05426.7 KFX89472.1 - 3e-13 49.7 3.0 3.4e-12 46.3 2.1 2.1 1 1 0 1 1 1 1 Alginate lyase Alginate_lyase2 PF08787.6 KFX89474.1 - 1.3e-42 146.0 0.0 1.5e-42 145.8 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase Laminin_G_3 PF13385.1 KFX89474.1 - 0.013 15.6 1.3 0.024 14.9 0.9 1.4 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Glyco_hydro_7 PF00840.15 KFX89475.1 - 4.3e-207 687.6 24.9 5e-207 687.4 17.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 GRAM PF02893.15 KFX89478.1 - 9.6e-18 63.4 0.0 2e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 GRAM domain WWbp PF10349.4 KFX89482.1 - 7e-18 65.6 5.3 8.9e-18 65.2 3.7 1.1 1 0 0 1 1 1 1 WW-domain ligand protein SPT16 PF08644.6 KFX89498.1 - 1.2e-57 194.0 0.4 1.7e-56 190.3 0.1 2.6 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 KFX89498.1 - 4.7e-54 182.3 0.1 1.5e-53 180.6 0.1 2.0 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 KFX89498.1 - 6.6e-21 74.8 0.0 1.3e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 KFX89498.1 - 9.8e-21 73.5 0.0 2.8e-20 72.0 0.0 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Ish1 PF10281.4 KFX89498.1 - 0.032 14.3 0.0 0.15 12.1 0.0 2.2 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein DUF2462 PF09495.5 KFX89499.1 - 2.7e-16 60.0 9.9 3.9e-16 59.5 6.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) ERG4_ERG24 PF01222.12 KFX89500.1 - 2.8e-138 461.0 17.1 3.2e-138 460.8 11.8 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family SRP-alpha_N PF04086.8 KFX89500.1 - 1.3 8.3 5.0 1.9 7.8 3.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Rubis-subs-bind PF09273.6 KFX89509.1 - 9.8e-18 64.2 0.4 2.1e-17 63.1 0.3 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 KFX89509.1 - 5.6e-13 49.5 0.0 3.1e-12 47.0 0.0 2.2 2 1 0 2 2 2 1 SET domain EPL1 PF10513.4 KFX89510.1 - 2.2e-28 99.4 6.7 2.2e-28 99.4 4.6 2.7 2 1 0 2 2 2 1 Enhancer of polycomb-like EF-hand_1 PF00036.27 KFX89511.1 - 2.4e-26 88.9 10.1 8.2e-07 27.8 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KFX89511.1 - 1.4e-24 85.9 2.3 6.3e-13 48.6 0.4 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFX89511.1 - 5.5e-21 72.5 4.1 3.8e-05 23.2 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KFX89511.1 - 7.5e-20 69.3 11.1 1.9e-06 26.9 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KFX89511.1 - 3.9e-15 55.1 12.3 1.4e-05 24.6 0.6 4.6 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KFX89511.1 - 4.9e-07 29.7 0.0 0.0006 19.8 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFX89511.1 - 1.9e-06 27.5 7.5 0.0024 17.6 0.3 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand P16-Arc PF04699.9 KFX89515.1 - 0.028 14.4 0.5 0.059 13.3 0.3 1.4 1 0 0 1 1 1 0 ARP2/3 complex 16 kDa subunit (p16-Arc) Pol_alpha_B_N PF08418.5 KFX89520.1 - 1.7 8.1 4.9 1.9 7.9 3.4 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Alpha_GJ PF03229.8 KFX89520.1 - 5.1 7.4 6.9 7.1 6.9 4.8 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J CDP-OH_P_transf PF01066.16 KFX89526.1 - 7.1e-13 48.7 1.7 1.1e-12 48.1 1.2 1.3 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DUF4345 PF14248.1 KFX89526.1 - 0.068 12.6 4.8 0.59 9.5 3.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4345) Metallopep PF12044.3 KFX89527.1 - 3.9e-166 552.7 0.0 4.9e-166 552.3 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 KFX89527.1 - 0.0011 18.8 0.2 0.007 16.2 0.0 2.3 2 1 0 2 2 2 1 Jacalin-like lectin domain Reprolysin_2 PF13574.1 KFX89527.1 - 0.021 14.9 1.9 0.039 14.0 0.3 2.0 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFX89527.1 - 0.026 14.4 1.8 0.057 13.3 1.3 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12 HSP70 PF00012.15 KFX89533.1 - 3.4e-10 38.4 0.2 1.9e-08 32.6 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein DUF2439 PF10382.4 KFX89533.1 - 0.018 15.2 0.1 1.5 9.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2439) Vps5 PF09325.5 KFX89539.1 - 0.0084 15.3 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Vps5 C terminal like DENN PF02141.16 KFX89543.1 - 6.3e-40 136.8 0.0 1.1e-39 136.1 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KFX89543.1 - 5.1e-05 23.1 0.0 0.00014 21.7 0.0 1.9 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.6 KFX89543.1 - 0.0059 16.9 4.3 0.0059 16.9 3.0 2.4 2 1 1 3 3 3 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Aminotran_5 PF00266.14 KFX89546.1 - 7.2e-13 48.0 0.0 8.5e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Ala_racemase_N PF01168.15 KFX89549.1 - 1.3e-42 145.8 0.0 1.6e-42 145.5 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Cupin_2 PF07883.6 KFX89551.1 - 2.5e-20 71.7 0.3 2e-09 36.8 0.1 2.2 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KFX89551.1 - 4.5e-16 57.9 1.6 3.5e-12 45.5 0.4 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 KFX89551.1 - 5.7e-06 26.0 0.1 0.029 14.0 0.0 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_1 PF00190.17 KFX89551.1 - 6.2e-06 25.7 0.0 0.00015 21.2 0.0 2.4 2 1 0 2 2 2 1 Cupin CENP-C_C PF11699.3 KFX89551.1 - 8.6e-05 22.4 0.0 0.00022 21.1 0.0 1.6 2 0 0 2 2 2 1 Mif2/CENP-C like DUF2697 PF10906.3 KFX89551.1 - 0.013 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2697) Cupin_6 PF12852.2 KFX89551.1 - 0.038 13.5 0.0 5.6 6.5 0.0 2.2 1 1 1 2 2 2 0 Cupin MannoseP_isomer PF01050.13 KFX89551.1 - 0.045 13.3 0.0 4.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase Sugar_tr PF00083.19 KFX89559.1 - 5.6e-75 252.6 23.5 5.6e-75 252.6 16.3 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter DUF2422 PF10337.4 KFX89559.1 - 6.1e-57 193.4 7.4 8.7e-56 189.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2422) NmrA PF05368.8 KFX89559.1 - 5e-30 104.4 0.0 2.3e-29 102.2 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family MFS_1 PF07690.11 KFX89559.1 - 8.6e-11 41.1 17.2 8.6e-11 41.1 11.9 4.5 2 2 1 3 3 3 2 Major Facilitator Superfamily NAD_binding_10 PF13460.1 KFX89559.1 - 3.7e-10 40.1 0.0 6.9e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding FUSC_2 PF13515.1 KFX89559.1 - 8.2e-10 38.6 22.0 8.2e-10 38.6 15.2 5.0 4 0 0 4 4 4 1 Fusaric acid resistance protein-like KR PF08659.5 KFX89559.1 - 0.0019 17.8 0.3 0.0053 16.4 0.0 1.8 2 0 0 2 2 2 1 KR domain 3Beta_HSD PF01073.14 KFX89559.1 - 0.015 14.0 0.0 0.024 13.3 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KFX89559.1 - 0.031 14.1 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Amidohydro_2 PF04909.9 KFX89560.1 - 7.9e-18 64.9 0.0 1e-17 64.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.13 KFX89561.1 - 3.9e-27 94.7 4.0 3.9e-27 94.7 2.7 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX89561.1 - 6.7e-10 38.7 9.2 1.3e-09 37.7 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hid1 PF12722.2 KFX89562.1 - 9.1e-252 837.6 0.3 3.4e-251 835.7 0.2 1.7 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 KFX89562.1 - 1.5e-82 277.8 0.1 2e-82 277.4 0.1 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein TMEM51 PF15345.1 KFX89562.1 - 1.2 8.7 5.1 2.1 8.0 3.5 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 TPR_10 PF13374.1 KFX89568.1 - 1.6e-101 329.7 0.0 4.2e-12 45.5 0.0 10.7 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_12 PF13424.1 KFX89568.1 - 2.8e-90 296.3 0.0 2.4e-18 65.8 0.0 7.0 1 1 6 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.1 KFX89568.1 - 1.8e-21 74.1 2.4 0.00023 20.7 0.0 7.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 KFX89568.1 - 1e-15 57.1 0.1 8.3e-05 22.1 0.0 5.9 5 0 0 5 5 5 3 TPR repeat TPR_17 PF13431.1 KFX89568.1 - 9.7e-15 53.4 5.5 0.56 10.5 0.0 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.23 KFX89568.1 - 3.7e-11 42.1 6.4 0.028 14.0 0.0 7.3 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_4 PF07721.9 KFX89568.1 - 7.1e-09 35.2 6.0 1.1 9.8 0.1 6.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFX89568.1 - 1.1e-08 34.3 10.9 0.1 12.5 0.0 8.6 10 0 0 10 10 9 2 Tetratricopeptide repeat NB-ARC PF00931.17 KFX89568.1 - 3.5e-08 32.6 0.0 2.2e-06 26.7 0.0 2.6 1 1 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.1 KFX89568.1 - 2e-06 27.1 9.2 2.3 8.2 0.0 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat DUF2664 PF10867.3 KFX89568.1 - 1.5e-05 25.4 1.0 58 4.3 0.0 7.7 8 1 1 9 9 9 0 Protein of unknown function (DUF2664) AAA_22 PF13401.1 KFX89568.1 - 0.00015 21.8 0.1 0.0012 19.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain TPR_6 PF13174.1 KFX89568.1 - 0.00031 21.0 10.1 8.7 7.0 0.0 8.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFX89568.1 - 0.00035 20.8 6.5 12 6.2 0.0 6.9 7 1 2 9 9 8 0 Tetratricopeptide repeat PPR_3 PF13812.1 KFX89568.1 - 0.00046 20.2 0.5 24 5.5 0.0 5.2 5 0 0 5 5 4 0 Pentatricopeptide repeat domain TPR_14 PF13428.1 KFX89568.1 - 0.0011 19.4 12.9 14 6.6 0.0 8.4 10 0 0 10 10 8 0 Tetratricopeptide repeat SNAP PF14938.1 KFX89568.1 - 0.013 14.6 0.1 0.93 8.5 0.0 2.9 2 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP TPR_16 PF13432.1 KFX89568.1 - 0.041 14.5 13.3 0.67 10.6 0.0 6.6 3 1 5 8 8 7 0 Tetratricopeptide repeat PPR PF01535.15 KFX89568.1 - 0.053 13.5 10.0 5.6 7.1 0.0 7.1 8 0 0 8 8 7 0 PPR repeat MFS_2 PF13347.1 KFX89572.1 - 3.6e-12 45.4 11.4 1e-11 43.9 7.9 1.7 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1_like PF12832.2 KFX89572.1 - 0.14 11.9 5.7 0.56 10.0 0.0 3.2 3 1 0 3 3 3 0 MFS_1 like family DUF1752 PF08550.5 KFX89579.1 - 7.1e-07 28.6 3.7 1.3e-06 27.8 2.6 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF849 PF05853.7 KFX89579.1 - 0.014 14.2 0.2 0.022 13.6 0.1 1.2 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) RhoGAP PF00620.22 KFX89581.1 - 3.6e-42 143.5 0.0 7.5e-42 142.5 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Hid1 PF12722.2 KFX89581.1 - 0.36 8.4 3.7 0.56 7.8 2.6 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein zf-H2C2_2 PF13465.1 KFX89599.1 - 7.7e-06 25.9 0.5 7.7e-06 25.9 0.3 3.6 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 KFX89599.1 - 0.00018 21.6 0.2 0.00018 21.6 0.1 3.7 4 1 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX89599.1 - 0.015 15.5 0.2 0.015 15.5 0.1 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFX89599.1 - 0.1 12.7 0.8 6.4 7.0 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFX89599.1 - 0.11 12.4 0.1 17 5.4 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Aldo_ket_red PF00248.16 KFX89600.1 - 4.5e-52 176.6 0.0 5.1e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.27 KFX89601.1 - 3e-33 112.4 4.7 1.4e-09 37.5 0.1 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 KFX89601.1 - 3.5e-05 22.1 0.3 0.00077 17.7 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KFX89601.1 - 0.018 13.3 0.0 0.79 7.9 0.0 2.1 1 1 1 2 2 2 0 Cytochrome D1 heme domain HRXXH PF13933.1 KFX89603.1 - 9.1e-96 320.0 0.0 1.1e-95 319.7 0.0 1.0 1 0 0 1 1 1 1 Putative peptidase family Zip PF02535.17 KFX89604.1 - 2.8e-36 125.1 14.7 2.8e-36 125.1 10.2 2.2 2 1 0 2 2 2 1 ZIP Zinc transporter CDP-OH_P_transf PF01066.16 KFX89608.1 - 1.2e-17 64.0 7.2 1.2e-17 64.0 5.0 3.0 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Retinin_C PF04527.7 KFX89610.1 - 0.048 13.6 0.2 0.081 12.9 0.1 1.3 1 0 0 1 1 1 0 Drosophila Retinin like protein LIM PF00412.17 KFX89616.1 - 1.4e-26 92.3 24.4 2.3e-10 40.3 1.8 3.7 4 0 0 4 4 4 3 LIM domain DUF2321 PF10083.4 KFX89616.1 - 0.021 14.3 0.5 0.021 14.3 0.3 2.6 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2321) DUF3725 PF12523.3 KFX89616.1 - 0.21 11.7 10.8 0.34 11.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3725) DUF3328 PF11807.3 KFX89617.1 - 4.7e-47 160.4 0.1 5.3e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PLA2_inh PF02988.10 KFX89628.1 - 0.13 12.7 0.3 0.42 11.0 0.0 1.9 2 0 0 2 2 2 0 Phospholipase A2 inhibitor PTR2 PF00854.16 KFX89633.1 - 5.1e-26 91.3 1.7 5.1e-26 91.3 1.2 2.2 2 1 0 2 2 2 1 POT family BCDHK_Adom3 PF10436.4 KFX89649.1 - 1.1e-68 229.8 0.0 4.3e-68 227.9 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KFX89649.1 - 4.9e-18 64.8 0.0 6.8e-17 61.1 0.0 2.5 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFX89649.1 - 0.015 14.9 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sorb PF02208.11 KFX89649.1 - 0.063 12.6 0.0 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 Sorbin homologous domain Ribosomal_L22 PF00237.14 KFX89649.1 - 0.1 12.5 0.0 3.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L22p/L17e BRO1 PF03097.13 KFX89650.1 - 2.8e-111 371.9 0.0 4.1e-111 371.3 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KFX89650.1 - 1.2e-69 234.4 0.0 2.3e-69 233.5 0.0 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF2360 PF10152.4 KFX89650.1 - 3.5 7.8 9.1 8.9 6.5 6.3 1.6 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) EMP24_GP25L PF01105.19 KFX89653.1 - 2.1e-51 174.2 0.0 2.4e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CTP_transf_2 PF01467.21 KFX89658.1 - 0.00072 19.6 0.3 1.1 9.3 0.0 3.2 3 1 0 3 3 3 2 Cytidylyltransferase Oxysterol_BP PF01237.13 KFX89658.1 - 0.42 9.0 4.1 0.64 8.4 2.8 1.3 1 0 0 1 1 1 0 Oxysterol-binding protein WD40 PF00400.27 KFX89664.1 - 6.6e-72 235.0 17.5 1.2e-11 44.0 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KFX89664.1 - 2.9e-11 42.2 0.4 8.6e-05 20.8 0.0 3.5 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFX89664.1 - 0.0082 14.9 0.2 1.7 7.3 0.0 2.9 1 1 1 2 2 2 2 Nup133 N terminal like DivIC PF04977.10 KFX89664.1 - 0.18 11.3 0.2 0.33 10.4 0.1 1.4 1 0 0 1 1 1 0 Septum formation initiator Na_Ca_ex PF01699.19 KFX89665.1 - 1.5e-48 163.9 34.0 1e-25 89.9 8.5 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein TFIIE_beta PF02186.10 KFX89666.1 - 1.3e-05 25.0 0.1 8.7e-05 22.4 0.1 2.2 2 1 0 2 2 2 1 TFIIE beta subunit core domain LZ_Tnp_IS66 PF13007.2 KFX89666.1 - 1.6 9.4 9.5 8.4 7.1 1.2 2.6 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain DUF3275 PF11679.3 KFX89666.1 - 2.3 7.7 4.8 4.5 6.8 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Ribosomal_60s PF00428.14 KFX89666.1 - 10 6.6 7.9 15 6.0 2.3 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein TPR_MLP1_2 PF07926.7 KFX89667.1 - 1.3e-28 99.3 20.4 1.3e-28 99.3 14.1 17.4 5 3 11 16 16 16 5 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 KFX89667.1 - 0.0034 17.1 14.1 0.0034 17.1 9.8 22.8 13 6 9 24 24 24 3 TATA element modulatory factor 1 DNA binding Hexapep PF00132.19 KFX89668.1 - 2.1e-11 42.7 8.8 7.1e-08 31.6 0.4 4.1 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KFX89668.1 - 0.00018 20.9 11.8 0.19 11.3 0.5 3.8 2 2 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Complex1_51K PF01512.12 KFX89669.1 - 2.5e-46 157.1 0.0 5.1e-46 156.1 0.0 1.5 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 KFX89669.1 - 3.6e-18 64.4 0.9 3.6e-18 64.4 0.7 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 KFX89669.1 - 9e-10 38.2 0.0 2e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 SLBB domain Complex1_LYR_2 PF13233.1 KFX89670.1 - 1.4e-22 80.0 0.4 1.7e-22 79.8 0.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Peptidase_M13_N PF05649.8 KFX89670.1 - 0.042 12.9 0.0 0.044 12.8 0.0 1.0 1 0 0 1 1 1 0 Peptidase family M13 Complex1_LYR PF05347.10 KFX89670.1 - 0.12 12.1 1.7 0.18 11.5 1.2 1.5 1 1 0 1 1 1 0 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFX89670.1 - 0.28 11.3 2.7 0.63 10.2 1.8 1.6 1 1 0 1 1 1 0 Complex1_LYR-like MMR_HSR1 PF01926.18 KFX89671.1 - 5.3e-20 71.5 0.0 8.2e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFX89671.1 - 7.3e-06 25.5 0.0 0.0001 21.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KFX89671.1 - 0.00039 20.2 0.1 0.041 13.6 0.3 2.3 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 KFX89671.1 - 0.0015 17.8 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 KFX89671.1 - 0.0043 16.2 0.0 0.0071 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 KFX89671.1 - 0.0074 15.5 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit IIGP PF05049.8 KFX89671.1 - 0.075 11.8 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AIG1 PF04548.11 KFX89671.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Sec39 PF08314.6 KFX89686.1 - 2.2e-135 452.3 0.0 2.5e-135 452.1 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.4 KFX89687.1 - 3.6e-05 23.6 0.0 4.3e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 KFX89687.1 - 0.011 15.8 0.2 0.019 15.0 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) COX17 PF05051.8 KFX89687.1 - 0.07 13.1 0.2 0.11 12.4 0.2 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Nucleoplasmin PF03066.10 KFX89688.1 - 0.098 12.1 1.6 0.19 11.2 1.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin GST_N_3 PF13417.1 KFX89689.1 - 3.4e-12 46.4 0.0 6.4e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFX89689.1 - 2e-11 43.7 0.0 3.8e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KFX89689.1 - 5.2e-11 42.3 0.0 1.1e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KFX89689.1 - 5.3e-11 42.5 0.0 1.1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFX89689.1 - 3.2e-09 36.5 0.0 6.8e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFX89689.1 - 8.8e-07 29.3 0.0 1.5e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-RING_5 PF14634.1 KFX89693.1 - 3.1e-05 23.5 0.6 0.00023 20.8 0.1 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFX89693.1 - 0.0064 16.1 1.0 0.013 15.1 0.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFX89693.1 - 0.011 15.7 1.8 0.018 15.0 0.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 KFX89693.1 - 0.028 14.3 1.9 0.12 12.2 0.7 2.1 2 0 0 2 2 2 0 FYVE zinc finger zf-RING_UBOX PF13445.1 KFX89693.1 - 0.034 13.8 0.1 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFX89693.1 - 0.035 13.9 1.6 0.069 13.0 0.1 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KFX89693.1 - 0.044 13.4 1.9 0.14 11.8 0.3 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFX89693.1 - 0.063 13.1 1.2 0.22 11.3 0.1 2.1 2 0 0 2 2 2 0 Ring finger domain Cullin_binding PF03556.10 KFX89694.1 - 3.2e-29 101.4 6.4 5.1e-29 100.7 4.4 1.3 1 0 0 1 1 1 1 Cullin binding Ank_2 PF12796.2 KFX89694.1 - 1.6e-07 31.5 0.0 3.2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) UBA_4 PF14555.1 KFX89694.1 - 5.6e-06 25.7 0.0 1.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Ank_4 PF13637.1 KFX89694.1 - 9.9e-05 22.7 0.0 0.00021 21.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 KFX89694.1 - 0.00015 21.4 0.0 0.00079 19.1 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 KFX89694.1 - 0.00045 20.1 0.0 0.0038 17.3 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 KFX89694.1 - 0.0018 18.4 0.0 0.0039 17.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ribosomal_S6 PF01250.12 KFX89695.1 - 2.8e-09 36.7 0.0 3.2e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 RDM PF11002.3 KFX89695.1 - 0.068 12.8 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 RFPL defining motif (RDM) Exotox-A_cataly PF09009.5 KFX89695.1 - 0.13 11.1 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Exotoxin A catalytic Amidohydro_1 PF01979.15 KFX89696.1 - 1e-13 51.6 0.2 3.7e-13 49.8 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.6 KFX89696.1 - 2.1e-07 30.5 0.0 3.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family SH3_9 PF14604.1 KFX89710.1 - 1.8e-05 24.2 0.1 4e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFX89710.1 - 0.0049 16.2 0.2 0.0098 15.2 0.1 1.4 1 0 0 1 1 1 1 SH3 domain Herpes_gE PF02480.11 KFX89710.1 - 0.008 14.4 0.0 0.014 13.6 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DAP10 PF07213.6 KFX89710.1 - 0.019 14.6 0.3 0.12 12.1 0.0 2.3 2 0 0 2 2 2 0 DAP10 membrane protein Gly-zipper_YMGG PF13441.1 KFX89710.1 - 0.85 9.1 16.9 2.1 7.8 2.7 2.4 2 0 0 2 2 2 0 YMGG-like Gly-zipper SKG6 PF08693.5 KFX89710.1 - 0.9 8.9 4.1 0.6 9.4 1.0 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain HAD PF12710.2 KFX89716.1 - 7.3e-13 49.1 0.0 9.9e-13 48.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFX89716.1 - 6.9e-06 26.3 0.0 2.4e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KFX89716.1 - 8.4e-05 21.8 0.0 0.068 12.3 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase PF00702.21 KFX89716.1 - 0.019 15.4 0.0 0.054 13.9 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 KFX89716.1 - 0.025 13.9 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) Solute_trans_a PF03619.11 KFX89728.1 - 6.7e-40 137.1 9.9 9.7e-40 136.5 6.9 1.2 1 0 0 1 1 1 1 Organic solute transporter Ostalpha YycC PF14174.1 KFX89728.1 - 0.43 10.3 2.5 0.78 9.4 0.8 2.0 2 0 0 2 2 2 0 YycC-like protein PS_Dcarbxylase PF02666.10 KFX89729.1 - 4.4e-57 192.6 0.0 5.4e-57 192.3 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase UcrQ PF02939.11 KFX89729.1 - 0.14 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 UcrQ family AMP-binding PF00501.23 KFX89730.1 - 4.9e-241 799.3 0.0 3.3e-85 286.0 0.0 3.4 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KFX89730.1 - 1e-144 481.0 0.0 1.4e-39 135.8 0.8 4.4 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.20 KFX89730.1 - 5e-32 109.9 0.3 6.7e-11 42.3 0.0 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site Tri3 PF07428.6 KFX89731.1 - 3.2e-11 42.6 0.1 1.1e-10 40.7 0.0 1.8 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 AATase PF07247.7 KFX89731.1 - 0.018 13.6 0.0 0.13 10.8 0.0 2.1 1 1 0 1 1 1 0 Alcohol acetyltransferase Condensation PF00668.15 KFX89731.1 - 0.031 13.1 0.1 0.36 9.6 0.0 2.2 2 0 0 2 2 2 0 Condensation domain CWC25 PF12542.3 KFX89732.1 - 4.3e-26 91.1 2.3 4.3e-26 91.1 1.6 3.4 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 KFX89732.1 - 1.6e-11 43.9 13.4 1.6e-11 43.9 9.3 3.9 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF2937 PF11157.3 KFX89732.1 - 0.58 9.4 4.5 1.1 8.6 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) PCI PF01399.22 KFX89733.1 - 2.6e-19 69.4 1.6 7.7e-19 67.9 0.1 2.4 2 1 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 KFX89733.1 - 2.1e-06 27.5 0.2 5e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 KFX89733.1 - 0.0032 17.1 0.3 3.5 7.6 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFX89733.1 - 0.014 15.2 0.0 11 6.0 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Cas_DxTHG PF09455.5 KFX89733.1 - 0.017 14.2 4.9 0.034 13.2 3.2 1.6 1 1 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family TPR_2 PF07719.12 KFX89733.1 - 0.049 13.5 1.6 0.73 9.9 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_10 PF12846.2 KFX89733.1 - 0.08 12.3 0.8 1.2 8.5 0.0 2.3 2 1 0 2 2 2 0 AAA-like domain CN_hydrolase PF00795.17 KFX89736.1 - 4.9e-31 107.5 0.0 6.4e-31 107.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Cyto_heme_lyase PF01265.12 KFX89739.1 - 6.4e-77 258.6 0.0 7.3e-77 258.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase tRNA-synt_1g PF09334.6 KFX89740.1 - 5.8e-137 456.5 0.0 1e-136 455.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KFX89740.1 - 2.1e-05 22.7 0.5 0.16 9.8 0.0 3.8 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) DZR PF12773.2 KFX89740.1 - 1.3 8.8 5.6 3.4 7.5 3.0 1.8 1 1 1 2 2 2 0 Double zinc ribbon Yae1_N PF09811.4 KFX89741.1 - 1.5e-08 33.9 5.3 2.4e-08 33.3 3.7 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal DUF2638 PF10937.3 KFX89742.1 - 4.1e-37 127.6 0.6 4.8e-37 127.4 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) Med18 PF09637.5 KFX89743.1 - 3e-25 89.2 0.0 3.4e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Med18 protein PNK3P PF08645.6 KFX89744.1 - 8.5e-51 171.5 0.0 1.3e-50 170.9 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 KFX89744.1 - 3.4e-18 65.8 0.0 1.6e-17 63.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain HAD_2 PF13419.1 KFX89744.1 - 0.00029 21.1 0.0 0.067 13.4 0.0 2.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Zeta_toxin PF06414.7 KFX89744.1 - 0.029 13.4 0.0 0.24 10.4 0.0 2.0 1 1 1 2 2 2 0 Zeta toxin DUF2390 PF09523.5 KFX89744.1 - 0.062 13.4 0.0 0.3 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) AAA_22 PF13401.1 KFX89744.1 - 0.099 12.7 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 KFX89744.1 - 0.16 11.1 0.2 3.1 6.9 0.1 2.2 1 1 1 2 2 2 0 Chromatin associated protein KTI12 DUF972 PF06156.8 KFX89747.1 - 0.13 12.5 1.1 0.15 12.3 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Peptidase_M48 PF01435.13 KFX89748.1 - 1.8e-49 168.3 0.0 3.1e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 KFX89748.1 - 0.00043 19.3 0.1 0.00082 18.4 0.1 1.4 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF2201_N PF13203.1 KFX89748.1 - 0.017 14.3 0.9 0.027 13.6 0.2 1.6 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF955 PF06114.8 KFX89748.1 - 0.14 11.9 0.2 0.92 9.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF955) GHMP_kinases_N PF00288.21 KFX89750.1 - 2e-19 69.3 0.1 6.3e-19 67.8 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KFX89750.1 - 1.3e-08 34.9 0.1 3.2e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 KFX89750.1 - 0.0085 15.3 0.0 0.021 14.1 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature PPTA PF01239.17 KFX89751.1 - 2e-42 140.8 10.3 8.8e-08 31.1 1.8 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat COesterase PF00135.23 KFX89755.1 - 1.3e-24 86.8 0.1 1.9e-24 86.2 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family Sterol_MT_C PF08498.5 KFX89755.1 - 4.1e-16 58.6 0.3 7.8e-16 57.7 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal CMAS PF02353.15 KFX89755.1 - 6.9e-16 58.1 0.0 1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 KFX89755.1 - 8.8e-15 54.9 0.0 1.6e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX89755.1 - 4.7e-12 45.7 0.0 7e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX89755.1 - 1.1e-10 41.4 0.0 1.8e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX89755.1 - 4e-10 39.9 0.0 8.5e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX89755.1 - 4.6e-10 39.8 0.0 1.6e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX89755.1 - 5.6e-10 39.7 0.1 4.7e-09 36.8 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX89755.1 - 1e-07 32.0 0.1 2.4e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX89755.1 - 1.3e-07 30.9 0.0 2.4e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KFX89755.1 - 4.8e-05 22.8 0.0 7.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Abhydrolase_3 PF07859.8 KFX89755.1 - 0.00044 19.9 0.0 0.0016 18.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold PCMT PF01135.14 KFX89755.1 - 0.0013 18.2 0.1 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 KFX89755.1 - 0.0045 16.5 0.0 0.0066 16.0 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 KFX89755.1 - 0.037 13.6 0.0 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 RrnaAD PF00398.15 KFX89755.1 - 0.037 13.0 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DOT1 PF08123.8 KFX89755.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 p450 PF00067.17 KFX89756.1 - 1.8e-24 86.1 0.0 2.3e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Phage_lysozyme PF00959.14 KFX89758.1 - 1.2e-12 48.0 0.0 2.3e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Phage lysozyme SH3_3 PF08239.6 KFX89758.1 - 4.8e-05 23.4 0.4 0.00049 20.2 0.3 2.3 2 0 0 2 2 2 1 Bacterial SH3 domain CHAP PF05257.11 KFX89759.1 - 3.5e-22 78.3 7.2 7.1e-22 77.3 5.0 1.5 1 0 0 1 1 1 1 CHAP domain SH3_3 PF08239.6 KFX89759.1 - 0.00026 21.1 1.4 0.00047 20.2 0.2 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain DUF2422 PF10337.4 KFX89761.1 - 0.1 11.3 0.1 0.19 10.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) zf-C2H2 PF00096.21 KFX89773.1 - 0.0036 17.5 14.2 1 9.8 0.0 3.9 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX89773.1 - 0.4 11.1 0.0 0.4 11.1 0.0 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger DUF1635 PF07795.6 KFX89774.1 - 0.15 11.3 0.1 0.17 11.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF221 PF02714.10 KFX89784.1 - 1.5e-107 359.2 27.9 4.1e-107 357.8 17.5 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KFX89784.1 - 4.5e-43 146.5 1.4 4.5e-43 146.5 0.9 2.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KFX89784.1 - 3.8e-34 116.4 0.1 2.7e-32 110.4 0.0 2.3 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 KFX89784.1 - 5.8e-26 90.8 0.4 9.5e-26 90.1 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) ODV-E18 PF10717.4 KFX89784.1 - 0.24 10.8 1.3 3.9 6.9 0.4 2.5 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Ank_2 PF12796.2 KFX89789.1 - 3.4e-64 213.1 7.9 2.4e-16 59.8 0.0 7.1 3 2 2 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFX89789.1 - 8.7e-55 179.9 28.0 5.8e-06 25.8 0.1 13.4 12 2 0 12 12 12 12 Ankyrin repeat Ank_4 PF13637.1 KFX89789.1 - 1.5e-46 155.9 12.3 1.1e-08 35.4 0.0 9.9 3 2 8 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX89789.1 - 2.7e-40 135.4 19.9 7.4e-09 35.5 0.0 8.1 5 3 3 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX89789.1 - 8.5e-40 130.8 12.5 0.0038 17.3 0.0 12.8 12 2 0 12 12 12 10 Ankyrin repeat Ank_2 PF12796.2 KFX89790.1 - 2.6e-85 280.8 5.8 1.7e-19 69.9 0.1 5.3 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFX89790.1 - 8.3e-77 249.4 8.0 5.4e-08 32.2 0.0 12.2 12 0 0 12 12 12 10 Ankyrin repeat Ank_3 PF13606.1 KFX89790.1 - 9.9e-62 198.7 3.6 6.8e-05 22.7 0.0 12.1 12 0 0 12 12 12 10 Ankyrin repeat Ank_4 PF13637.1 KFX89790.1 - 4.3e-53 176.8 9.0 1.4e-09 38.1 0.0 8.7 3 3 6 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX89790.1 - 3.8e-47 157.2 7.0 7.1e-08 32.4 0.1 9.4 4 3 5 9 9 9 9 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 KFX89790.1 - 0.015 14.8 4.7 19 4.6 0.0 5.3 2 2 3 6 6 6 0 Shigella flexneri OspC protein NDUFA12 PF05071.11 KFX89792.1 - 0.00014 22.2 0.0 0.00019 21.8 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.1 KFX89793.1 - 5.9e-13 48.6 0.0 3.1e-05 23.7 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KFX89793.1 - 6.4e-07 28.9 0.0 0.00073 19.2 0.0 2.6 2 1 0 2 2 2 2 Phospholipase D Active site motif Glyco_hydro_35 PF01301.14 KFX89795.1 - 8.2e-69 232.3 2.5 2.2e-68 230.9 1.8 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 Cellulase PF00150.13 KFX89795.1 - 0.00017 20.9 0.4 0.0003 20.1 0.3 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.19 KFX89795.1 - 0.0039 16.5 0.0 0.0056 15.9 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Glyco_hydro_49 PF03718.8 KFX89796.1 - 2.9e-195 649.7 15.0 3.7e-195 649.3 10.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 49 Glyco_hydro_28 PF00295.12 KFX89796.1 - 0.0022 17.0 0.0 0.0045 15.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Alpha-amylase PF00128.19 KFX89797.1 - 4.9e-98 328.4 0.0 8.2e-98 327.6 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.3 KFX89797.1 - 0.029 14.4 0.0 0.068 13.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Sugar_tr PF00083.19 KFX89798.1 - 1.8e-83 280.6 24.0 2.1e-83 280.4 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX89798.1 - 5.9e-17 61.4 36.2 5.9e-12 44.9 9.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX89798.1 - 6e-05 21.6 4.2 6e-05 21.6 2.9 3.8 2 2 2 4 4 4 3 MFS/sugar transport protein Fungal_trans PF04082.13 KFX89799.1 - 3.1e-13 49.2 5.8 4.4e-13 48.7 4.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ATP-synt_C PF00137.16 KFX89800.1 - 6.3e-11 42.0 12.4 6.3e-11 42.0 8.6 1.7 2 0 0 2 2 2 1 ATP synthase subunit C CAP59_mtransfer PF11735.3 KFX89801.1 - 2.1e-84 282.5 0.0 3.7e-84 281.7 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 APH PF01636.18 KFX89801.1 - 5e-16 59.1 0.9 1.7e-15 57.3 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX89801.1 - 0.0026 17.3 0.0 0.0068 16.0 0.0 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase DUF605 PF04652.11 KFX89801.1 - 0.013 14.9 11.9 0.021 14.2 8.3 1.2 1 0 0 1 1 1 0 Vta1 like Fructosamin_kin PF03881.9 KFX89801.1 - 0.091 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase DUF221 PF02714.10 KFX89803.1 - 4.6e-95 318.1 13.6 7.1e-95 317.5 9.4 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KFX89803.1 - 4.3e-37 127.1 0.2 1.1e-36 125.7 0.1 1.7 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KFX89803.1 - 6.1e-16 58.7 0.0 1.3e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) SGL PF08450.7 KFX89804.1 - 7.2e-65 218.7 0.1 1e-64 218.3 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Reg_prop PF07494.6 KFX89804.1 - 0.057 13.4 0.1 1.8 8.8 0.0 3.0 2 0 0 2 2 2 0 Two component regulator propeller Clr5 PF14420.1 KFX89805.1 - 1.2e-10 41.1 0.2 2.1e-10 40.3 0.2 1.4 1 0 0 1 1 1 1 Clr5 domain Myb_DNA-bind_2 PF08914.6 KFX89805.1 - 0.006 16.3 0.8 0.015 15.1 0.5 1.7 1 0 0 1 1 1 1 Rap1 Myb domain Fungal_trans PF04082.13 KFX89806.1 - 3.4e-16 58.9 0.3 6e-16 58.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX89806.1 - 9.3e-08 31.8 9.6 1.6e-07 31.0 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_C9 PF01707.11 KFX89806.1 - 0.2 11.2 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C9 NmrA PF05368.8 KFX89807.1 - 4.5e-25 88.2 0.0 5.7e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX89807.1 - 2.9e-10 40.4 0.5 1.6e-09 38.0 0.1 2.0 2 0 0 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KFX89807.1 - 0.05 12.5 0.1 2 7.2 0.1 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain DapB_N PF01113.15 KFX89807.1 - 0.068 13.0 0.5 0.14 12.1 0.1 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 KFX89807.1 - 0.08 12.5 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.19 KFX89807.1 - 0.096 12.9 0.1 0.26 11.6 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 KFX89807.1 - 0.11 12.3 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.16 KFX89807.1 - 0.11 11.8 0.4 0.31 10.4 0.1 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFX89807.1 - 0.15 10.7 0.1 0.23 10.1 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family zf-RING_2 PF13639.1 KFX89808.1 - 3.5e-16 58.7 6.1 3.5e-16 58.7 4.3 2.3 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFX89808.1 - 8.9e-10 38.4 4.9 8.9e-10 38.4 3.4 2.0 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFX89808.1 - 8.1e-09 35.0 2.5 8.1e-09 35.0 1.7 2.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFX89808.1 - 3.8e-08 33.3 1.2 3.8e-08 33.3 0.8 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KFX89808.1 - 4.8e-08 32.6 3.3 4.8e-08 32.6 2.3 2.7 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFX89808.1 - 1.5e-07 30.9 2.3 1.5e-07 30.9 1.6 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFX89808.1 - 8.5e-05 22.1 0.7 0.00053 19.6 0.5 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 KFX89808.1 - 0.00018 21.3 1.0 0.00018 21.3 0.7 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KFX89808.1 - 0.0035 16.8 5.4 0.0035 16.8 3.7 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Vps39_2 PF10367.4 KFX89808.1 - 0.0071 16.5 1.2 0.027 14.6 0.1 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Prok-RING_4 PF14447.1 KFX89808.1 - 0.022 14.2 2.2 0.022 14.2 1.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 RINGv PF12906.2 KFX89808.1 - 0.16 12.0 4.4 0.53 10.3 3.0 1.9 1 0 0 1 1 1 0 RING-variant domain PRP38 PF03371.10 KFX89822.1 - 6e-61 205.0 0.0 7.5e-61 204.7 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Ank_2 PF12796.2 KFX89823.1 - 3.2e-50 168.3 1.7 1.3e-18 67.0 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFX89823.1 - 5.1e-50 167.0 5.3 3.2e-13 49.8 0.0 6.1 1 1 6 7 7 7 5 Ankyrin repeats (many copies) Ank PF00023.25 KFX89823.1 - 7.1e-46 151.8 5.8 9.3e-11 40.9 0.0 7.1 6 1 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 KFX89823.1 - 2.1e-38 129.4 13.0 1.4e-10 41.0 0.0 6.9 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX89823.1 - 6.6e-37 121.8 0.0 8e-08 31.8 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Pkinase PF00069.20 KFX89823.1 - 7.3e-29 100.7 0.0 1.1e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX89823.1 - 4.1e-15 55.5 0.0 6.7e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.12 KFX89824.1 - 0.0068 15.4 0.0 0.2 10.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 KFX89824.1 - 0.0075 15.4 0.0 0.029 13.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Siah-Interact_N PF09032.6 KFX89824.1 - 0.049 13.6 0.9 0.22 11.5 0.1 2.4 2 0 0 2 2 2 0 Siah interacting protein, N terminal DUF3933 PF13069.1 KFX89824.1 - 0.085 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3933) eIF-5a PF01287.15 KFX89825.1 - 3.3e-05 23.7 0.0 8.8e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold DUF948 PF06103.6 KFX89826.1 - 0.0037 17.0 5.3 0.13 12.0 0.5 3.7 2 1 1 3 3 3 3 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 KFX89826.1 - 0.039 13.1 23.0 0.33 10.0 0.7 3.6 2 1 2 4 4 4 0 Reovirus sigma C capsid protein Tim17 PF02466.14 KFX89826.1 - 0.22 11.5 1.2 5 7.1 0.1 2.5 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family DUF4336 PF14234.1 KFX89827.1 - 2e-17 63.2 0.0 6.2e-13 48.5 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) DUF4166 PF13761.1 KFX89827.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4166) Amidase PF01425.16 KFX89834.1 - 1.2e-81 274.7 1.1 1.5e-81 274.5 0.8 1.0 1 0 0 1 1 1 1 Amidase Lentivirus_VIF PF05851.6 KFX89834.1 - 0.00095 17.9 0.0 0.0013 17.4 0.0 1.1 1 0 0 1 1 1 1 Lentivirus virion infectivity factor (VIF) CVNH PF08881.5 KFX89839.1 - 2.1e-21 76.0 0.0 2.5e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 CVNH domain Bac_rhamnosid PF05592.6 KFX89840.1 - 1.1e-14 53.6 0.0 7.3e-06 24.4 0.0 3.3 3 1 0 3 3 3 3 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 KFX89840.1 - 0.11 11.1 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF608 DcpS_C PF11969.3 KFX89841.1 - 7.9e-16 58.3 4.1 3.1e-15 56.4 1.8 2.4 2 1 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 KFX89841.1 - 1.1e-13 51.4 0.0 2.9e-13 50.1 0.0 1.6 1 1 0 1 1 1 1 HIT domain HA2 PF04408.18 KFX89842.1 - 5.8e-18 64.7 0.2 3e-17 62.4 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KFX89842.1 - 1.5e-14 53.7 0.0 3.7e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KFX89842.1 - 5.1e-14 51.9 0.4 3.8e-13 49.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RWD PF05773.17 KFX89842.1 - 9.1e-13 48.0 0.0 1.8e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 KFX89842.1 - 2.4e-09 36.9 0.1 4.6e-09 35.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFX89842.1 - 0.00016 21.8 0.2 0.00053 20.1 0.1 1.9 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 KFX89842.1 - 0.00097 19.0 0.0 0.0041 16.9 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_29 PF13555.1 KFX89842.1 - 0.0024 17.3 0.3 0.017 14.5 0.0 2.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain DND1_DSRM PF14709.1 KFX89842.1 - 0.0068 16.6 0.1 0.017 15.3 0.1 1.7 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 T2SE PF00437.15 KFX89842.1 - 0.0091 14.9 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein Aldo_ket_red PF00248.16 KFX89842.1 - 0.014 14.2 0.0 0.03 13.1 0.0 1.4 1 0 0 1 1 1 0 Aldo/keto reductase family AAA_23 PF13476.1 KFX89842.1 - 0.017 15.4 0.0 0.051 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KFX89842.1 - 0.028 13.5 0.0 0.062 12.4 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 KFX89842.1 - 0.058 13.1 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF2533 PF10752.4 KFX89842.1 - 0.08 13.2 0.5 0.26 11.6 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) adh_short PF00106.20 KFX89852.1 - 1e-34 119.8 3.7 1.5e-34 119.3 2.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX89852.1 - 2.5e-20 73.3 0.3 3.2e-20 72.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX89852.1 - 3.1e-18 66.0 2.9 4.2e-18 65.6 2.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFX89852.1 - 6.8e-07 28.9 0.9 2.4e-05 23.8 0.1 2.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX89852.1 - 2.7e-05 24.2 2.3 0.00018 21.5 1.6 2.1 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 KFX89852.1 - 0.00061 18.9 0.6 0.002 17.2 0.2 1.9 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 KFX89852.1 - 0.00091 18.9 1.4 0.0025 17.5 0.9 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.10 KFX89852.1 - 0.0016 18.0 1.1 0.0028 17.2 0.8 1.3 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Polysacc_synt_2 PF02719.10 KFX89852.1 - 0.0022 16.9 0.6 0.0036 16.2 0.4 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KFX89852.1 - 0.003 16.8 2.1 0.1 11.8 1.4 2.1 2 0 0 2 2 2 1 NmrA-like family ApbA PF02558.11 KFX89852.1 - 0.009 15.4 0.1 0.016 14.6 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KFX89852.1 - 0.0095 15.6 1.3 0.017 14.7 0.9 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HEM4 PF02602.10 KFX89852.1 - 0.057 12.6 0.6 0.098 11.8 0.4 1.5 1 1 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Wax2_C PF12076.3 KFX89852.1 - 0.064 12.9 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 WAX2 C-terminal domain MFS_1 PF07690.11 KFX89853.1 - 4.4e-36 124.3 34.4 1.3e-35 122.8 23.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1049 PF06305.6 KFX89853.1 - 5.2 6.6 0.0 5.2 6.6 0.0 5.4 6 1 1 7 7 7 0 Protein of unknown function (DUF1049) Peptidase_M36 PF02128.10 KFX89854.1 - 0.084 11.6 0.2 0.11 11.2 0.2 1.1 1 0 0 1 1 1 0 Fungalysin metallopeptidase (M36) VKOR PF07884.9 KFX89854.1 - 1 9.1 18.7 0.11 12.4 0.8 3.1 1 1 2 3 3 3 0 Vitamin K epoxide reductase family FAD_binding_3 PF01494.14 KFX89855.1 - 2.6e-14 53.0 2.4 3.1e-10 39.6 0.2 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KFX89855.1 - 0.0014 18.6 0.0 0.0031 17.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFX89855.1 - 0.005 17.2 0.0 0.095 13.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX89855.1 - 0.044 13.5 0.0 0.097 12.4 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.13 KFX89855.1 - 0.056 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.19 KFX89855.1 - 0.1 11.4 0.7 0.21 10.4 0.2 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Ribosomal_S8e PF01201.17 KFX89857.1 - 2.7e-37 127.8 3.8 8.2e-36 123.0 2.7 2.2 1 1 0 1 1 1 1 Ribosomal protein S8e DUF3959 PF13105.1 KFX89857.1 - 3.5 6.8 7.7 1.1 8.4 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) LCD1 PF09798.4 KFX89857.1 - 8.6 4.2 9.0 11 3.8 6.2 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein Y_phosphatase3 PF13350.1 KFX89858.1 - 2.9e-29 102.4 0.1 3.7e-14 53.3 0.0 3.3 3 0 0 3 3 3 2 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KFX89858.1 - 1.4e-07 31.5 0.4 2.9e-07 30.4 0.3 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 KFX89858.1 - 2.1e-07 30.4 0.0 1.9e-05 24.0 0.0 2.9 3 0 0 3 3 3 1 Tyrosine phosphatase family DSPc PF00782.15 KFX89858.1 - 0.00073 19.1 0.0 0.041 13.4 0.0 3.0 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFX89858.1 - 0.001 18.4 0.0 0.0045 16.3 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Myotub-related PF06602.9 KFX89858.1 - 0.022 13.5 0.0 0.036 12.8 0.0 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain ABC_membrane PF00664.18 KFX89859.1 - 3e-48 164.6 44.9 4.3e-28 98.5 15.7 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 KFX89859.1 - 3.4e-45 153.7 0.0 4e-26 91.9 0.0 3.0 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 KFX89859.1 - 1.8e-06 27.3 0.9 0.019 14.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KFX89859.1 - 5.4e-06 26.3 0.2 0.064 13.2 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.1 KFX89859.1 - 7.7e-06 26.0 0.7 0.37 10.7 0.1 4.4 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KFX89859.1 - 2.3e-05 24.4 0.2 0.054 13.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.7 KFX89859.1 - 4.1e-05 22.7 0.1 0.017 14.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin SMC_N PF02463.14 KFX89859.1 - 4.8e-05 22.7 1.0 0.31 10.2 0.1 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain Miro PF08477.8 KFX89859.1 - 5.2e-05 23.7 2.8 0.15 12.5 0.1 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_23 PF13476.1 KFX89859.1 - 0.00051 20.4 2.9 0.82 9.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 KFX89859.1 - 0.0016 17.6 1.4 0.44 9.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFX89859.1 - 0.0017 17.8 0.2 0.72 9.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 KFX89859.1 - 0.0028 17.1 0.0 0.21 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain DUF87 PF01935.12 KFX89859.1 - 0.0028 17.4 1.8 0.28 10.9 0.3 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_30 PF13604.1 KFX89859.1 - 0.0028 17.2 0.4 2.1 7.8 0.1 2.5 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 KFX89859.1 - 0.0031 16.3 0.9 0.88 8.2 0.1 2.4 2 0 0 2 2 2 2 ArgK protein AAA_22 PF13401.1 KFX89859.1 - 0.0066 16.5 0.5 9.5 6.3 0.1 3.3 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KFX89859.1 - 0.014 16.1 6.1 1.9 9.3 0.0 3.6 3 1 0 3 3 2 0 AAA domain AAA_19 PF13245.1 KFX89859.1 - 0.063 13.0 0.9 0.37 10.5 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 KFX89859.1 - 0.077 12.4 0.6 11 5.4 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.9 KFX89859.1 - 0.084 12.5 0.6 12 5.6 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 KFX89859.1 - 0.53 9.2 0.0 16 4.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.18 KFX89859.1 - 0.54 10.0 11.9 0.32 10.8 0.5 3.1 3 0 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.12 KFX89859.1 - 0.7 9.3 2.7 10 5.5 0.2 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Frag1 PF10277.4 KFX89860.1 - 2.7e-43 147.9 10.2 3.2e-43 147.7 7.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family SLAC1 PF03595.12 KFX89860.1 - 0.034 12.8 13.0 0.029 13.0 8.1 1.5 1 1 0 1 1 1 0 Voltage-dependent anion channel Bac_Ubq_Cox PF01654.12 KFX89860.1 - 0.096 11.0 7.6 0.027 12.9 0.5 2.6 2 1 1 3 3 3 0 Bacterial Cytochrome Ubiquinol Oxidase Tetraspannin PF00335.15 KFX89860.1 - 0.27 10.4 3.9 0.24 10.6 0.2 2.1 2 0 0 2 2 2 0 Tetraspanin family Cation_ATPase_C PF00689.16 KFX89860.1 - 1.8 8.0 13.2 0.054 13.0 5.0 1.5 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus SUR7 PF06687.7 KFX89860.1 - 4.7 6.7 8.3 37 3.7 0.0 2.8 1 1 0 2 2 2 0 SUR7/PalI family MIR PF02815.14 KFX89861.1 - 0.0007 19.1 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 MIR domain PMT PF02366.13 KFX89862.1 - 2.7e-81 272.5 16.8 3.4e-81 272.2 11.6 1.1 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KFX89862.1 - 8.2e-10 38.5 0.4 3.8e-08 33.0 0.1 2.1 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.1 KFX89862.1 - 0.00064 19.6 12.4 0.00064 19.6 8.6 2.2 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Pkinase PF00069.20 KFX89864.1 - 1e-63 214.9 0.0 1.5e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX89864.1 - 1.9e-27 95.9 0.0 2.6e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFX89864.1 - 0.0054 15.8 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFX89864.1 - 0.0066 15.4 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFX89864.1 - 0.082 12.2 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 KFX89864.1 - 0.082 12.6 0.4 1.4 8.5 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family NMO PF03060.10 KFX89866.1 - 1.5e-05 24.3 0.1 1.6e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase PC_rep PF01851.17 KFX89866.1 - 0.035 14.3 0.0 0.45 10.8 0.0 2.2 2 0 0 2 2 2 0 Proteasome/cyclosome repeat RNA_pol_L_2 PF13656.1 KFX89867.1 - 1.4e-22 78.9 0.0 1.9e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KFX89867.1 - 1.2e-10 40.3 0.0 1.7e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain LSM PF01423.17 KFX89868.1 - 8.9e-19 66.8 0.1 1e-18 66.6 0.1 1.0 1 0 0 1 1 1 1 LSM domain DUF4444 PF14563.1 KFX89868.1 - 6.5 6.2 5.9 4.1 6.8 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4444) DNA_pol_A_exo1 PF01612.15 KFX89869.1 - 3.7e-14 52.6 0.0 5.3e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease WD40 PF00400.27 KFX89870.1 - 1.1e-09 37.7 2.3 2.1e-05 24.2 0.0 4.1 3 1 0 3 3 3 2 WD domain, G-beta repeat R3H-assoc PF13902.1 KFX89873.1 - 7.7e-09 35.6 0.1 7.7e-09 35.6 0.1 2.6 3 1 1 4 4 4 1 R3H-associated N-terminal domain R3H PF01424.17 KFX89873.1 - 0.009 15.6 0.1 0.009 15.6 0.1 2.4 3 0 0 3 3 3 1 R3H domain FUSC PF04632.7 KFX89873.1 - 0.078 11.3 0.1 0.099 11.0 0.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Peptidase_M28 PF04389.12 KFX89874.1 - 3.9e-28 98.3 0.3 9.6e-28 97.1 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 KFX89874.1 - 3.6e-07 29.8 0.0 6.7e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF1774 PF08611.5 KFX89876.1 - 4.5e-31 106.8 1.6 4.5e-31 106.8 1.1 2.7 2 1 2 4 4 4 1 Fungal protein of unknown function (DUF1774) FixQ PF05545.6 KFX89876.1 - 0.09 12.4 0.5 0.09 12.4 0.3 3.8 4 0 0 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ Herpes_UL36 PF03586.8 KFX89876.1 - 0.48 9.4 2.2 5.7 5.9 0.1 2.1 2 0 0 2 2 2 0 Herpesvirus UL36 tegument protein HMA PF00403.21 KFX89880.1 - 4.3e-14 52.3 0.5 6e-14 51.9 0.1 1.4 2 0 0 2 2 2 1 Heavy-metal-associated domain Prenyltrans_1 PF13243.1 KFX89884.1 - 9.8e-25 86.6 0.6 2.5e-16 59.6 0.1 5.5 5 1 1 6 6 6 4 Prenyltransferase-like Prenyltrans PF00432.16 KFX89884.1 - 2.7e-24 84.3 16.0 4.7e-08 32.4 0.2 6.1 7 0 0 7 7 7 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KFX89884.1 - 1.7e-23 83.1 3.6 3.3e-15 56.4 0.1 5.2 3 1 2 5 5 5 4 Prenyltransferase-like Pec_lyase PF09492.5 KFX89884.1 - 0.0012 18.1 0.7 3.4 6.7 0.0 4.4 4 1 0 4 4 4 2 Pectic acid lyase TP6A_N PF04406.9 KFX89885.1 - 1.7e-21 75.6 0.0 3.1e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2240 PF09999.4 KFX89885.1 - 0.0044 16.4 0.0 0.014 14.8 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2240) Ank_2 PF12796.2 KFX89886.1 - 9.3e-45 150.8 5.3 1.1e-16 60.9 0.2 8.0 5 2 2 8 8 8 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFX89886.1 - 3.2e-33 111.8 13.1 2.3e-06 27.1 0.0 11.2 12 0 0 12 12 12 7 Ankyrin repeat Ank_3 PF13606.1 KFX89886.1 - 5.4e-30 100.4 0.7 0.00049 20.0 0.0 12.3 13 0 0 13 13 13 5 Ankyrin repeat Ank_5 PF13857.1 KFX89886.1 - 2.6e-29 100.5 4.5 0.0021 18.2 0.0 8.9 7 1 1 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFX89886.1 - 2e-25 88.6 7.4 5.2e-05 23.6 0.2 9.7 8 1 1 9 9 9 6 Ankyrin repeats (many copies) P19Arf_N PF07392.7 KFX89886.1 - 0.27 11.4 0.0 0.64 10.2 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus Glyco_hydro_31 PF01055.21 KFX89887.1 - 4.5e-155 516.8 3.3 6.2e-155 516.3 2.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KFX89887.1 - 9.5e-24 83.0 2.3 1e-23 82.9 0.3 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like NDK PF00334.14 KFX89888.1 - 5e-30 104.0 0.0 6.6e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Mito_carr PF00153.22 KFX89895.1 - 2.1e-57 190.8 0.8 4.6e-20 71.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein BTB PF00651.26 KFX89896.1 - 5.5e-07 29.5 0.0 1.9e-05 24.5 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain FAT PF02259.18 KFX89899.1 - 2.2e-76 257.1 5.7 3.6e-76 256.4 4.0 1.4 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 KFX89899.1 - 8.7e-28 97.3 0.1 1.7e-27 96.4 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 KFX89899.1 - 2.9e-08 32.9 0.2 5.7e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 FATC domain TPR_1 PF00515.23 KFX89899.1 - 0.096 12.3 0.7 9.8 5.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Fungal_trans PF04082.13 KFX89900.1 - 5e-29 100.9 0.0 2e-28 98.9 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain 2OG-FeII_Oxy_3 PF13640.1 KFX89900.1 - 9.8e-09 35.6 0.0 3.3e-08 33.9 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.13 KFX89900.1 - 1.3e-06 28.2 13.6 2.2e-06 27.4 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2OG-FeII_Oxy_4 PF13661.1 KFX89900.1 - 9.5e-06 25.1 0.0 2.3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Gal4_dimer PF03902.8 KFX89900.1 - 0.17 11.8 0.1 0.63 10.0 0.0 2.0 2 0 0 2 2 2 0 Gal4-like dimerisation domain Metallophos PF00149.23 KFX89901.1 - 6.6e-16 58.2 1.2 1.1e-15 57.6 0.8 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFX89901.1 - 0.00041 20.2 0.0 0.0014 18.4 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PCMT PF01135.14 KFX89902.1 - 4.6e-48 163.5 0.0 5e-47 160.1 0.0 2.1 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pkinase PF00069.20 KFX89902.1 - 6.3e-19 68.1 0.0 2.1e-18 66.3 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Methyltransf_31 PF13847.1 KFX89902.1 - 8.7e-08 31.8 0.0 1.9e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Pkinase_Tyr PF07714.12 KFX89902.1 - 3.2e-07 29.6 0.0 1.6e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Methyltransf_18 PF12847.2 KFX89902.1 - 3.3e-07 30.8 0.0 7.2e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX89902.1 - 3e-05 24.0 0.0 6.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KFX89902.1 - 0.00014 21.5 0.0 0.00054 19.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX89902.1 - 0.0022 17.7 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 KFX89902.1 - 0.0038 16.2 0.0 0.0083 15.1 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase Ubie_methyltran PF01209.13 KFX89902.1 - 0.0073 15.4 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 KFX89902.1 - 0.01 14.8 0.0 0.032 13.2 0.0 1.7 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.1 KFX89902.1 - 0.056 13.8 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KFX89902.1 - 0.11 13.0 0.1 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Complex1_LYR PF05347.10 KFX89903.1 - 1.9e-08 33.9 0.0 3.1e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFX89903.1 - 1.1e-07 31.9 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KFX89903.1 - 2.4e-05 24.7 0.0 3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like TauD PF02668.11 KFX89904.1 - 7.9e-20 71.6 0.0 1.1e-19 71.0 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Bombolitin PF08096.6 KFX89904.1 - 0.31 11.2 0.0 0.31 11.2 0.0 2.2 2 0 0 2 2 2 0 Bombolitin family Rad9 PF04139.8 KFX89908.1 - 1.6e-60 204.3 0.2 1.9e-60 204.1 0.2 1.0 1 0 0 1 1 1 1 Rad9 LRR_4 PF12799.2 KFX89909.1 - 0.01 15.4 15.4 0.67 9.6 0.2 4.9 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) adh_short PF00106.20 KFX89910.1 - 3.1e-13 49.9 0.9 6.8e-13 48.8 0.6 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX89910.1 - 4.4e-09 36.2 0.3 9.3e-09 35.1 0.1 1.7 1 1 1 2 2 2 1 KR domain adh_short_C2 PF13561.1 KFX89910.1 - 7.1e-06 25.9 0.6 9.7e-06 25.5 0.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFX89910.1 - 0.00074 19.0 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Phos_pyr_kin PF08543.7 KFX89911.1 - 2.4e-82 275.8 2.5 3.7e-82 275.2 1.7 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 KFX89911.1 - 7.5e-27 94.4 0.3 1.2e-26 93.8 0.2 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 KFX89911.1 - 2.9e-07 29.9 0.4 4.5e-07 29.2 0.3 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase SDH_sah PF01972.11 KFX89911.1 - 0.095 11.4 0.9 0.18 10.5 0.6 1.4 1 0 0 1 1 1 0 Serine dehydrogenase proteinase HK PF02110.10 KFX89911.1 - 0.12 11.4 4.0 0.42 9.7 0.0 2.8 3 0 0 3 3 3 0 Hydroxyethylthiazole kinase family TENA_THI-4 PF03070.11 KFX89912.1 - 5e-14 52.5 0.0 5.3e-14 52.4 0.0 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family LIM PF00412.17 KFX89914.1 - 1.5e-15 57.0 19.4 8.3e-10 38.5 2.7 2.3 2 0 0 2 2 2 2 LIM domain Zn-ribbon_8 PF09723.5 KFX89914.1 - 0.00057 19.7 18.7 0.05 13.5 1.0 4.3 4 0 0 4 4 4 2 Zinc ribbon domain zf-CHY PF05495.7 KFX89914.1 - 0.00064 19.8 20.0 0.01 15.9 4.5 2.7 1 1 2 3 3 3 2 CHY zinc finger DZR PF12773.2 KFX89914.1 - 0.0013 18.4 19.5 7.1e+03 -3.1 13.6 4.6 1 1 0 1 1 1 0 Double zinc ribbon Cytochrom_CIII PF02085.11 KFX89914.1 - 0.088 12.9 13.1 5.8 7.0 0.6 2.3 1 1 1 2 2 2 0 Class III cytochrome C family zinc_ribbon_2 PF13240.1 KFX89914.1 - 0.21 11.1 17.6 0.27 10.7 0.1 5.6 5 1 0 5 5 5 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 KFX89914.1 - 0.28 10.5 19.7 0.52 9.6 0.7 4.7 4 1 1 5 5 5 0 TFIIB zinc-binding Cytochrom_c3_2 PF14537.1 KFX89914.1 - 2.4 8.5 19.3 1.5 9.2 4.1 3.2 1 1 1 2 2 2 0 Cytochrome c3 E6 PF00518.12 KFX89914.1 - 7.1 7.0 16.3 4 7.8 3.9 3.3 2 1 1 3 3 3 0 Early Protein (E6) zf-ribbon_3 PF13248.1 KFX89914.1 - 8.6 5.7 22.6 0.37 10.0 0.9 5.3 3 2 1 4 4 4 0 zinc-ribbon domain Hpt PF01627.18 KFX89919.1 - 2.1e-14 53.2 0.2 8e-14 51.4 0.1 1.8 2 0 0 2 2 2 1 Hpt domain DUF3680 PF12441.3 KFX89919.1 - 0.006 16.4 3.0 0.29 11.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3680) Carb_anhydrase PF00194.16 KFX89919.1 - 0.13 11.2 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic-type carbonic anhydrase SCF PF02404.10 KFX89919.1 - 0.17 11.0 0.6 0.23 10.6 0.3 1.3 1 1 0 1 1 1 0 Stem cell factor Sigma70_ner PF04546.8 KFX89919.1 - 0.92 9.0 6.7 0.61 9.6 0.4 2.0 1 1 1 2 2 2 0 Sigma-70, non-essential region SPO22 PF08631.5 KFX89940.1 - 0.056 12.5 0.0 0.075 12.1 0.0 1.1 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like HMG_box PF00505.14 KFX89941.1 - 1.8e-15 56.9 0.8 4e-15 55.8 0.5 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFX89941.1 - 6.7e-15 55.2 0.9 1.6e-14 54.0 0.6 1.7 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.25 KFX89941.1 - 2.2e-10 40.5 0.0 3.9e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFX89941.1 - 6.5e-08 32.3 0.5 1.8e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) FKBP_C PF00254.23 KFX89943.1 - 4.6e-27 93.8 0.1 6e-27 93.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase BATS PF06968.8 KFX89945.1 - 8.2e-26 89.6 0.0 1.9e-25 88.4 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 KFX89945.1 - 5.1e-14 52.7 0.0 1.1e-13 51.7 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily APH PF01636.18 KFX89945.1 - 9.2e-09 35.3 0.0 6.3e-08 32.6 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX89945.1 - 6.2e-08 32.4 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase HET PF06985.6 KFX89946.1 - 3.8e-26 91.9 0.0 6.4e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APH PF01636.18 KFX89947.1 - 6e-12 45.8 1.7 8.4e-11 42.0 1.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX89947.1 - 8.7e-06 25.4 0.1 6.1e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.17 KFX89947.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family MFS_1 PF07690.11 KFX89948.1 - 1e-44 152.6 40.8 1.8e-44 151.9 28.3 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KFX89948.1 - 1.1e-10 40.3 11.3 1.1e-10 40.3 7.8 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ank_2 PF12796.2 KFX89954.1 - 2.1e-27 95.2 1.6 9.2e-16 57.9 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFX89954.1 - 1.6e-15 56.0 2.0 4.4e-10 38.8 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KFX89954.1 - 1.6e-15 56.7 2.7 5.3e-10 39.2 0.3 3.0 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX89954.1 - 5e-15 54.1 0.6 5.8e-08 32.2 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 KFX89954.1 - 1.2e-12 47.9 2.2 1.1e-09 38.5 0.2 2.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) ParA PF10609.4 KFX89956.1 - 2.8e-35 120.0 0.2 4.7e-35 119.3 0.2 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KFX89956.1 - 7.6e-16 58.0 0.0 1.1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 KFX89956.1 - 1.4e-06 27.6 0.0 3.7e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.1 KFX89956.1 - 4.5e-06 26.6 0.0 3.1e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 KFX89956.1 - 4.7e-05 22.5 1.0 6.5e-05 22.1 0.3 1.5 2 0 0 2 2 2 1 Anion-transporting ATPase ArgK PF03308.11 KFX89956.1 - 0.0012 17.6 0.3 0.002 16.9 0.2 1.2 1 0 0 1 1 1 1 ArgK protein AAA_25 PF13481.1 KFX89956.1 - 0.0039 16.6 0.1 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain YhjQ PF06564.7 KFX89956.1 - 0.0054 16.1 0.3 0.0088 15.4 0.2 1.5 1 1 0 1 1 1 1 YhjQ protein DUF258 PF03193.11 KFX89956.1 - 0.019 14.1 1.0 0.038 13.1 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 APS_kinase PF01583.15 KFX89956.1 - 0.062 12.9 0.1 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_26 PF13500.1 KFX89956.1 - 0.23 11.0 1.2 11 5.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ribonucleas_3_3 PF14622.1 KFX89957.1 - 1.4e-22 80.0 0.0 2.5e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like KAT11 PF08214.6 KFX89958.1 - 3.7e-96 322.2 0.0 4.5e-96 321.9 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Glyco_hydro_16 PF00722.16 KFX89959.1 - 1e-42 145.5 1.0 1.6e-42 144.8 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TPR_12 PF13424.1 KFX89962.1 - 2.7e-05 24.0 8.8 0.01 15.7 0.9 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFX89962.1 - 0.00055 19.5 0.9 1.3 8.9 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFX89962.1 - 0.0014 18.3 0.7 1.5 8.9 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFX89962.1 - 0.022 14.4 3.0 0.42 10.2 1.4 2.6 1 1 0 1 1 1 0 TPR repeat TPR_14 PF13428.1 KFX89962.1 - 0.023 15.3 0.3 7.2 7.5 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Ifi-6-16 PF06140.8 KFX89963.1 - 0.00011 21.8 1.0 0.00043 20.0 0.7 2.0 1 0 0 1 1 1 1 Interferon-induced 6-16 family Esterase_phd PF10503.4 KFX89964.1 - 4.9e-23 81.5 1.3 2.4e-22 79.2 0.9 1.9 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KFX89964.1 - 2.8e-14 52.8 2.1 3.8e-14 52.4 1.4 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFX89964.1 - 2.1e-05 24.3 0.3 3.1e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX89964.1 - 0.00013 21.9 1.4 0.00065 19.6 1.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KFX89964.1 - 0.0007 18.4 1.9 0.0024 16.6 1.3 1.8 1 1 0 1 1 1 1 Carboxylesterase family zf-PHD-like PF15446.1 KFX89972.1 - 7.2e-70 233.7 7.1 1.7e-69 232.5 5.0 1.7 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 KFX89972.1 - 1.8e-58 197.6 0.0 2.8e-58 197.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 KFX89972.1 - 3.6e-15 55.5 0.9 8.3e-15 54.3 0.6 1.6 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 KFX89972.1 - 1.7e-12 46.9 0.0 5.5e-12 45.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 KFX89972.1 - 7.6e-08 31.9 0.7 0.00045 19.8 0.1 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.24 KFX89972.1 - 1.4e-05 24.6 0.0 2.7e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD PF00628.24 KFX89972.1 - 4.1e-05 23.1 3.1 4.1e-05 23.1 2.1 3.3 2 1 2 4 4 4 2 PHD-finger ResIII PF04851.10 KFX89972.1 - 7.4e-05 22.6 0.0 0.00035 20.4 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1087 PF06465.8 KFX89972.1 - 0.012 15.5 0.0 0.038 13.9 0.0 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) PHD_2 PF13831.1 KFX89972.1 - 0.093 12.0 11.6 0.0093 15.2 3.4 2.7 2 1 0 2 2 2 0 PHD-finger C1_1 PF00130.17 KFX89972.1 - 1.2 8.8 8.0 0.55 10.0 1.0 3.1 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TRAUB PF08164.7 KFX89973.1 - 0.083 13.0 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Apoptosis-antagonizing transcription factor, C-terminal ECH PF00378.15 KFX89976.1 - 2.9e-26 92.0 0.0 4.7e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Fungal_trans PF04082.13 KFX89976.1 - 1.6e-10 40.2 0.0 3.2e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_5 PF12695.2 KFX89988.1 - 5e-17 62.0 0.1 9.3e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 KFX89988.1 - 4.3e-12 45.0 0.0 8.4e-08 30.9 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.2 KFX89988.1 - 6.9e-10 39.1 1.7 1.2e-09 38.3 1.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KFX89988.1 - 3.1e-06 26.2 0.0 5.9e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme PGAP1 PF07819.8 KFX89988.1 - 0.0028 17.2 0.0 0.0045 16.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 KFX89988.1 - 0.0071 16.1 0.0 0.25 11.1 0.0 2.4 2 0 0 2 2 2 1 Putative lysophospholipase Lipase_3 PF01764.20 KFX89988.1 - 0.036 13.6 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase PF07224.6 KFX89988.1 - 0.06 12.1 0.1 0.76 8.5 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase DLH PF01738.13 KFX89988.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S9 PF00326.16 KFX89988.1 - 0.15 11.3 0.5 1 8.5 0.2 2.3 2 1 0 2 2 2 0 Prolyl oligopeptidase family HET PF06985.6 KFX89989.1 - 4.6e-22 78.6 5.1 6.6e-19 68.4 0.5 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_hydro_71 PF03659.9 KFX89990.1 - 1.3e-58 198.2 0.8 2.3e-58 197.5 0.6 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 71 MFS_1 PF07690.11 KFX89991.1 - 2e-24 85.9 35.8 2e-24 85.9 24.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX89991.1 - 1.1e-06 27.5 24.2 0.00021 20.0 0.7 3.3 2 2 0 3 3 3 2 Sugar (and other) transporter Sugar_tr PF00083.19 KFX89994.1 - 1.2e-87 294.3 18.1 1.4e-87 294.1 12.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX89994.1 - 3.4e-24 85.2 17.0 3.4e-24 85.2 11.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Granulin PF00396.13 KFX89995.1 - 4 7.6 20.9 9.3 6.4 4.9 2.4 1 1 1 2 2 2 0 Granulin SHR3_chaperone PF08229.6 KFX89996.1 - 1.3e-71 239.6 0.0 1.5e-71 239.4 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 PAP2 PF01569.16 KFX89997.1 - 5.3e-19 68.1 1.1 1.3e-18 66.9 0.4 1.9 2 0 0 2 2 2 1 PAP2 superfamily PHD PF00628.24 KFX89998.1 - 5.1e-11 42.0 5.4 7.2e-11 41.6 3.7 1.2 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 KFX89998.1 - 0.042 13.9 0.6 0.068 13.3 0.4 1.3 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 KFX89998.1 - 0.092 12.7 3.8 0.16 12.0 2.4 1.6 1 1 0 1 1 1 0 RING-like domain TPR_12 PF13424.1 KFX90000.1 - 4.9e-10 39.1 3.2 0.00022 21.0 0.1 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFX90000.1 - 3e-06 27.4 0.4 0.024 14.9 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFX90000.1 - 0.00083 18.9 0.0 14 5.7 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFX90000.1 - 0.0011 18.6 4.2 5.9 7.0 0.1 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_4 PF07721.9 KFX90000.1 - 0.0052 17.0 3.4 0.22 12.0 0.3 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFX90000.1 - 0.0097 16.4 1.1 11 6.9 0.1 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFX90000.1 - 0.046 13.6 0.1 21 5.1 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KFX90000.1 - 0.052 13.6 0.3 0.49 10.5 0.1 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 KFX90000.1 - 0.057 13.0 0.0 39 4.0 0.0 3.6 3 0 0 3 3 3 0 TPR repeat TPR_6 PF13174.1 KFX90000.1 - 0.12 12.8 0.0 1.1 9.9 0.0 2.6 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFX90000.1 - 0.14 11.7 0.3 5.8 6.6 0.0 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Mur_ligase_M PF08245.7 KFX90001.1 - 3.4e-07 30.4 0.0 1.1e-06 28.8 0.0 1.8 1 1 0 1 1 1 1 Mur ligase middle domain Corona_6B_7B PF03262.8 KFX90001.1 - 0.042 13.0 0.0 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 Coronavirus 6B/7B protein Zip PF02535.17 KFX90018.1 - 6.5e-18 64.7 4.6 7.2e-18 64.6 3.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter ABC2_membrane_3 PF12698.2 KFX90018.1 - 0.066 12.2 4.0 0.086 11.8 2.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Methyltransf_16 PF10294.4 KFX90021.1 - 1e-17 64.1 0.0 1.4e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KFX90021.1 - 4.4e-06 27.2 0.1 9.6e-06 26.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 KFX90021.1 - 0.00013 21.1 0.0 0.0002 20.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 KFX90021.1 - 0.00014 21.6 0.0 0.0002 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX90021.1 - 0.00014 22.2 0.0 0.00026 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX90021.1 - 0.001 18.6 0.0 0.2 11.2 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain MTS PF05175.9 KFX90021.1 - 0.0089 15.4 0.0 0.034 13.5 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase small domain GidB PF02527.10 KFX90021.1 - 0.011 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G NNMT_PNMT_TEMT PF01234.12 KFX90021.1 - 0.025 13.5 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_12 PF08242.7 KFX90021.1 - 0.037 14.5 0.1 0.1 13.0 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Aldedh PF00171.17 KFX90022.1 - 4.5e-176 585.7 0.5 5.1e-176 585.5 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans_2 PF11951.3 KFX90023.1 - 9.9e-35 119.8 0.3 1.3e-34 119.4 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX90023.1 - 7e-08 32.2 9.3 7e-08 32.2 6.5 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribonuc_L-PSP PF01042.16 KFX90024.1 - 5.4e-20 71.3 0.0 6.2e-20 71.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP AA_permease_2 PF13520.1 KFX90025.1 - 1.4e-30 106.2 28.4 1.7e-30 105.9 19.7 1.1 1 0 0 1 1 1 1 Amino acid permease DnaJ PF00226.26 KFX90050.1 - 1.1e-11 44.2 0.0 1.5e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pex14_N PF04695.8 KFX90050.1 - 0.042 13.8 1.9 0.047 13.7 1.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Phostensin PF13914.1 KFX90050.1 - 0.27 11.3 3.6 0.18 11.9 1.3 1.5 2 0 0 2 2 2 0 Phostensin PP1-binding and SH3-binding region MSA-2c PF12238.3 KFX90050.1 - 0.6 9.7 4.1 0.77 9.3 2.8 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c EF1_GNE PF00736.14 KFX90051.1 - 1e-30 105.2 1.8 1.7e-30 104.5 1.2 1.3 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KFX90051.1 - 1e-14 54.3 7.2 3e-14 52.8 5.0 1.9 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 KFX90051.1 - 0.0019 18.6 0.0 0.0059 17.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFX90051.1 - 0.026 14.5 0.1 0.081 12.9 0.0 1.9 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain TPR_12 PF13424.1 KFX90052.1 - 4.1e-41 138.8 37.6 1.9e-10 40.4 0.6 4.6 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 KFX90052.1 - 3.1e-27 93.6 25.5 4.4e-06 26.4 0.1 7.1 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 KFX90052.1 - 1.8e-16 58.5 0.1 0.046 13.5 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 KFX90052.1 - 2.3e-14 51.9 5.6 0.045 13.5 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 KFX90052.1 - 3.5e-14 52.8 18.7 0.0029 17.9 0.2 6.8 3 1 4 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 KFX90052.1 - 1.8e-13 49.3 2.0 0.2 11.6 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFX90052.1 - 1.1e-12 47.4 8.8 0.00011 21.8 0.5 4.4 3 1 1 4 4 4 4 TPR repeat TPR_16 PF13432.1 KFX90052.1 - 1.7e-12 47.6 9.3 0.00024 21.6 0.2 5.0 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 KFX90052.1 - 1.3e-11 44.0 10.6 0.5 11.1 0.1 7.1 3 1 2 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 KFX90052.1 - 7.4e-11 42.0 11.7 0.0024 17.9 1.5 4.8 1 1 3 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 KFX90052.1 - 1.4e-10 40.3 0.1 2 8.5 0.0 6.2 6 0 0 6 6 6 3 PPR repeat TPR_6 PF13174.1 KFX90052.1 - 7.6e-10 38.5 0.6 5.5 7.6 0.0 6.3 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 KFX90052.1 - 1.1e-09 38.2 25.0 0.054 13.6 0.8 6.8 2 1 5 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.23 KFX90052.1 - 8.6e-09 34.6 0.8 1.4 8.6 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat PPR_3 PF13812.1 KFX90052.1 - 1.4e-06 28.1 3.0 2.1 8.8 0.0 6.0 6 0 0 6 6 5 1 Pentatricopeptide repeat domain TPR_17 PF13431.1 KFX90052.1 - 2.7e-06 27.1 9.6 3.9 7.9 0.1 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat NB-ARC PF00931.17 KFX90052.1 - 8.1e-06 24.8 0.0 1.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Abhydrolase_6 PF12697.2 KFX90052.1 - 1e-05 25.5 0.0 3.2e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family PPR_2 PF13041.1 KFX90052.1 - 0.00024 21.0 0.5 55 3.8 0.0 5.8 6 0 0 6 6 6 0 PPR repeat family Abhydrolase_9 PF10081.4 KFX90052.1 - 0.0004 19.1 0.0 0.029 13.1 0.0 2.7 2 0 0 2 2 2 1 Alpha/beta-hydrolase family PPR_1 PF12854.2 KFX90052.1 - 0.00057 19.3 0.0 34 4.0 0.0 5.0 5 0 0 5 5 5 0 PPR repeat LCAT PF02450.10 KFX90052.1 - 0.00059 18.9 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF2305 PF10230.4 KFX90052.1 - 0.0011 18.4 0.2 0.044 13.1 0.0 2.8 3 0 0 3 3 3 1 Uncharacterised conserved protein (DUF2305) AAA_22 PF13401.1 KFX90052.1 - 0.0018 18.4 0.0 0.014 15.5 0.0 2.6 2 0 0 2 2 1 1 AAA domain Abhydrolase_5 PF12695.2 KFX90052.1 - 0.002 17.8 0.0 0.01 15.6 0.0 2.2 2 0 0 2 2 1 1 Alpha/beta hydrolase family Ribonuc_red_lgN PF00317.16 KFX90052.1 - 0.003 17.3 1.6 0.63 9.8 0.0 3.8 3 1 0 3 3 3 1 Ribonucleotide reductase, all-alpha domain PGAP1 PF07819.8 KFX90052.1 - 0.0044 16.6 0.0 0.014 15.0 0.0 1.8 2 0 0 2 2 1 1 PGAP1-like protein ATP13 PF12921.2 KFX90052.1 - 0.0074 15.6 0.6 6.2 6.1 0.0 4.0 3 1 1 4 4 4 0 Mitochondrial ATPase expression Cutinase PF01083.17 KFX90052.1 - 0.099 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Cutinase DUF2411 PF10304.4 KFX90052.1 - 0.5 9.9 4.5 13 5.4 0.1 3.9 4 0 0 4 4 3 0 Domain of unknown function (DUF2411) TPR_4 PF07721.9 KFX90052.1 - 1.1 9.9 12.5 84 4.0 0.1 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_3 PF07720.7 KFX90052.1 - 8.2 6.3 10.7 41 4.1 0.2 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Mito_carr PF00153.22 KFX90053.1 - 7.6e-40 134.5 10.4 2.2e-17 62.5 0.5 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Bromodomain PF00439.20 KFX90054.1 - 1.3e-36 124.3 0.3 6.3e-22 77.2 0.1 2.5 2 0 0 2 2 2 2 Bromodomain PGA_cap PF09587.5 KFX90056.1 - 6.9 5.9 10.7 0.13 11.6 1.9 2.0 2 0 0 2 2 2 0 Bacterial capsule synthesis protein PGA_cap IU_nuc_hydro PF01156.14 KFX90057.1 - 3.2e-57 194.1 0.0 6.6e-46 156.9 0.0 2.1 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase LSM PF01423.17 KFX90058.1 - 0.00039 19.9 0.0 0.00054 19.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain Rhomboid PF01694.17 KFX90059.1 - 1.3e-19 70.6 8.0 2.7e-19 69.6 5.5 1.4 1 0 0 1 1 1 1 Rhomboid family PhoD PF09423.5 KFX90059.1 - 7.6e-08 31.3 0.0 1.4e-05 23.8 0.0 2.5 2 1 0 2 2 2 2 PhoD-like phosphatase PYRIN PF02758.11 KFX90059.1 - 0.34 10.6 0.0 2.7 7.7 0.0 2.2 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain HHH_5 PF14520.1 KFX90060.1 - 5.4e-05 23.2 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain Sod_Cu PF00080.15 KFX90063.1 - 1.2e-19 70.8 1.2 1.6e-19 70.4 0.7 1.3 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) LSM PF01423.17 KFX90064.1 - 4.8e-20 70.8 0.0 5.4e-20 70.7 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KFX90064.1 - 0.039 13.8 0.0 0.045 13.6 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain VCBS PF13517.1 KFX90068.1 - 3.3e-38 129.8 62.7 6.8e-11 42.3 1.3 8.7 4 2 6 10 10 10 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KFX90068.1 - 2.9e-20 71.3 43.3 1.5e-05 24.5 0.3 7.6 7 0 0 7 7 7 6 FG-GAP repeat TcdB_toxin_midN PF12256.3 KFX90068.1 - 1.1e-11 44.5 14.0 0.018 14.4 0.0 6.3 5 2 2 7 7 7 4 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_2 PF13472.1 KFX90068.1 - 1.4e-10 41.6 0.7 3.7e-10 40.2 0.0 2.1 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFX90068.1 - 8.1e-10 38.9 0.2 1.9e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase C2 PF00168.25 KFX90072.1 - 5.1e-68 224.9 1.5 2.2e-17 62.6 0.0 5.7 5 0 0 5 5 5 5 C2 domain TRP PF06011.7 KFX90073.1 - 1.6e-86 290.6 27.2 4.1e-85 285.9 18.9 2.0 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KFX90073.1 - 5.4e-23 81.5 0.2 8.1e-23 81.0 0.1 1.3 1 0 0 1 1 1 1 ML-like domain Strabismus PF06638.6 KFX90073.1 - 7.2 4.8 4.7 11 4.1 3.3 1.2 1 0 0 1 1 1 0 Strabismus protein NAD_binding_8 PF13450.1 KFX90074.1 - 4.6e-08 32.9 0.1 9.1e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFX90074.1 - 7.1e-05 22.7 0.3 0.00051 19.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFX90074.1 - 8e-05 21.8 0.1 0.00012 21.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFX90074.1 - 0.0001 21.3 0.4 0.0001 21.3 0.3 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFX90074.1 - 0.00011 20.7 0.3 0.00011 20.7 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 KFX90074.1 - 0.00017 21.6 0.2 0.00036 20.6 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFX90074.1 - 0.00032 19.8 0.1 0.00047 19.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 KFX90074.1 - 0.0006 18.9 0.2 0.0006 18.9 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KFX90074.1 - 0.0013 18.5 0.1 0.0024 17.6 0.1 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KFX90074.1 - 0.0023 16.9 1.4 0.0042 16.0 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KFX90074.1 - 0.0023 16.8 0.9 0.0023 16.8 0.6 1.8 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 KFX90074.1 - 0.025 13.2 0.1 0.037 12.6 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 KFX90074.1 - 0.11 11.3 0.1 0.18 10.6 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Methyltransf_23 PF13489.1 KFX90076.1 - 4.2e-11 42.8 0.0 6.1e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX90076.1 - 0.068 13.6 0.0 0.098 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF3701 PF12482.3 KFX90076.1 - 6.3 6.6 7.1 0.7 9.6 1.8 1.7 1 1 1 2 2 2 0 Phage integrase protein Ank_2 PF12796.2 KFX90080.1 - 2.4e-116 380.3 44.0 2e-18 66.4 0.6 8.3 3 2 6 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 KFX90080.1 - 1.6e-90 292.6 50.5 1.8e-06 27.4 0.0 19.0 19 0 0 19 19 19 17 Ankyrin repeat Ank_4 PF13637.1 KFX90080.1 - 3.3e-78 256.7 16.8 6.9e-08 32.7 0.0 16.3 2 2 14 16 16 16 16 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX90080.1 - 1.2e-58 189.2 22.2 0.00091 19.2 0.0 17.9 18 0 0 18 18 18 15 Ankyrin repeat Ank_5 PF13857.1 KFX90080.1 - 3.4e-47 157.4 30.1 4.5e-05 23.5 0.1 13.1 6 4 7 14 14 14 11 Ankyrin repeats (many copies) NPV_P10 PF05531.7 KFX90080.1 - 0.0021 18.2 0.4 0.0096 16.1 0.0 2.1 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF3710 PF12502.3 KFX90080.1 - 0.8 8.9 9.4 8.2 5.7 0.0 6.0 3 3 4 7 7 7 0 Protein of unknown function (DUF3710) Ins_P5_2-kin PF06090.7 KFX90082.1 - 2.9e-41 141.5 0.0 3.5e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Ufd2P_core PF10408.4 KFX90091.1 - 1.1e-189 631.6 12.0 1.4e-189 631.4 8.3 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 KFX90091.1 - 8.7e-21 73.6 0.8 2.7e-20 72.0 0.5 2.0 1 0 0 1 1 1 1 U-box domain DUF1977 PF09320.6 KFX90092.1 - 3.1e-24 85.2 0.1 4.9e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 KFX90092.1 - 9.8e-21 73.2 0.5 2e-20 72.2 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain Acetyltransf_7 PF13508.1 KFX90094.1 - 5.8e-07 29.5 0.0 9.8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFX90094.1 - 1.7e-05 24.6 0.1 3.9e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX90094.1 - 0.004 17.1 0.1 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Ank_2 PF12796.2 KFX90095.1 - 7.8e-50 167.1 0.7 1.9e-17 63.3 0.0 4.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFX90095.1 - 6e-35 118.4 3.2 1.4e-08 34.6 0.0 6.4 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 KFX90095.1 - 3.3e-34 114.9 4.1 1e-05 25.0 0.0 7.8 7 1 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 KFX90095.1 - 7.5e-31 105.9 1.2 1.8e-09 37.8 0.1 5.8 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX90095.1 - 1.1e-21 74.7 0.2 0.0018 18.3 0.0 8.2 8 0 0 8 8 8 4 Ankyrin repeat FAD_binding_3 PF01494.14 KFX90095.1 - 1.7e-14 53.6 0.1 1.2e-13 50.8 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain DBD_Tnp_Hermes PF10683.4 KFX90095.1 - 0.04 13.3 0.1 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain DUF2387 PF09526.5 KFX90095.1 - 0.094 12.6 0.7 0.21 11.5 0.5 1.5 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) DUF974 PF06159.8 KFX90096.1 - 5.1e-45 153.8 0.0 5.6e-45 153.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF974) PRCC PF10253.4 KFX90098.1 - 0.18 12.4 6.4 0.35 11.5 2.1 2.3 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting zinc_ribbon_6 PF14599.1 KFX90099.1 - 6.9e-26 89.8 0.6 9.7e-26 89.3 0.4 1.2 1 0 0 1 1 1 1 Zinc-ribbon FYDLN_acid PF09538.5 KFX90099.1 - 0.54 10.8 17.4 1.1 9.8 12.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Nop14 PF04147.7 KFX90099.1 - 6.7 4.4 18.3 8.4 4.1 12.7 1.0 1 0 0 1 1 1 0 Nop14-like family MOZART1 PF12554.3 KFX90100.1 - 4.1e-24 83.7 0.9 4.9e-24 83.5 0.6 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated WXG100 PF06013.7 KFX90100.1 - 0.089 12.8 0.1 11 6.1 0.0 2.1 2 0 0 2 2 2 0 Proteins of 100 residues with WXG GFA PF04828.9 KFX90101.1 - 1.8e-18 66.2 0.4 9e-18 64.0 0.3 2.0 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 KFX90101.1 - 0.027 13.9 0.7 0.027 13.9 0.5 2.7 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Ish1 PF10281.4 KFX90101.1 - 0.22 11.6 2.9 0.63 10.1 2.0 1.9 1 1 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Nudix_N_2 PF14803.1 KFX90101.1 - 5.2 6.8 7.8 0.74 9.5 0.1 2.7 3 0 0 3 3 3 0 Nudix N-terminal IKI3 PF04762.7 KFX90102.1 - 0 1105.8 0.0 0 1105.6 0.0 1.0 1 0 0 1 1 1 1 IKI3 family DUF3984 PF13136.1 KFX90103.1 - 8.8e-66 222.3 23.5 2.3e-65 220.9 16.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3984) Corona_nucleoca PF00937.13 KFX90103.1 - 0.002 17.1 2.7 0.002 17.1 1.8 2.2 2 0 0 2 2 2 1 Coronavirus nucleocapsid protein DENN PF02141.16 KFX90106.1 - 1.6e-56 190.9 0.0 2.9e-56 190.1 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 KFX90106.1 - 4.9e-17 61.6 0.0 1.2e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 KFX90106.1 - 4.4e-16 58.7 0.7 4.4e-16 58.7 0.5 2.1 2 0 0 2 2 2 1 dDENN domain C1_1 PF00130.17 KFX90106.1 - 0.0052 16.4 4.1 0.0091 15.6 2.8 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.11 KFX90106.1 - 0.0079 16.2 3.9 0.014 15.4 2.7 1.4 1 0 0 1 1 1 1 C1 domain PHD PF00628.24 KFX90106.1 - 0.023 14.3 2.4 0.044 13.4 1.7 1.4 1 0 0 1 1 1 0 PHD-finger C1_3 PF07649.7 KFX90106.1 - 0.031 14.2 3.6 0.054 13.5 2.5 1.4 1 0 0 1 1 1 0 C1-like domain OrfB_Zn_ribbon PF07282.6 KFX90106.1 - 1.7 8.3 4.2 4 7.1 2.9 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain TPT PF03151.11 KFX90129.1 - 3.1e-17 62.6 11.0 3.1e-17 62.6 7.6 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KFX90129.1 - 1.8e-05 24.7 9.8 1.8e-05 24.7 6.8 2.9 2 1 1 3 3 3 1 EamA-like transporter family CRPA PF05745.6 KFX90129.1 - 0.067 12.9 0.2 0.067 12.9 0.2 1.9 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Tuberculin PF12198.3 KFX90129.1 - 0.094 12.6 0.2 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Theoretical tuberculin protein AMP-binding PF00501.23 KFX90132.1 - 2.5e-66 223.8 0.0 3.4e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX90132.1 - 9.7e-10 39.2 0.1 2.1e-09 38.2 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Melittin PF01372.12 KFX90132.1 - 0.12 11.7 0.5 0.34 10.2 0.4 1.8 1 0 0 1 1 1 0 Melittin PIG-S PF10510.4 KFX90133.1 - 5.1e-134 447.7 0.0 6.3e-134 447.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Ribosomal_L36 PF00444.13 KFX90134.1 - 1.4e-18 66.5 8.2 2.8e-18 65.5 5.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L36 Complex1_LYR PF05347.10 KFX90135.1 - 2.9e-15 55.7 0.1 5.1e-15 55.0 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFX90135.1 - 4.8e-14 52.3 1.2 5.7e-14 52.0 0.1 1.6 1 1 0 2 2 2 1 Complex1_LYR-like Acetyltransf_1 PF00583.19 KFX90136.1 - 1.2e-11 44.4 0.0 1.8e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFX90136.1 - 2.8e-06 27.3 0.1 4.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFX90136.1 - 0.0001 22.0 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KFX90136.1 - 0.0052 16.8 0.0 0.0072 16.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFX90136.1 - 0.0061 16.5 0.0 0.0094 15.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFX90136.1 - 0.0087 15.9 0.0 0.015 15.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Sec10 PF07393.6 KFX90137.1 - 2e-63 214.7 0.1 4e-63 213.7 0.0 1.4 1 1 0 1 1 1 1 Exocyst complex component Sec10 GAS PF13851.1 KFX90137.1 - 0.0016 17.6 0.4 0.0036 16.5 0.3 1.5 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.7 KFX90137.1 - 0.045 13.5 0.1 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus V-ATPase_C PF03223.10 KFX90137.1 - 0.066 12.1 0.4 0.24 10.2 0.2 2.0 1 1 1 2 2 2 0 V-ATPase subunit C Prenyltransf PF01255.14 KFX90138.1 - 1.8e-06 27.2 0.0 9.5e-05 21.6 0.0 2.1 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase IBR PF01485.16 KFX90139.1 - 2.2e-10 40.2 36.4 8.3e-08 31.9 2.9 3.1 3 0 0 3 3 3 2 IBR domain V_ATPase_I PF01496.14 KFX90139.1 - 6.4 4.5 9.0 0.18 9.6 0.2 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family MFS_1 PF07690.11 KFX90140.1 - 2e-37 128.7 57.3 8.2e-36 123.4 37.6 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX90140.1 - 2.8e-11 42.6 15.0 2.8e-11 42.6 10.4 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter Ferric_reduct PF01794.14 KFX90148.1 - 4.6e-19 68.7 13.7 7.7e-19 68.0 6.3 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KFX90148.1 - 1.6e-11 43.9 0.0 2.6e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KFX90148.1 - 1.3e-07 31.6 0.0 1.8e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Sdh_cyt PF01127.17 KFX90148.1 - 0.0015 18.3 7.7 0.0015 18.3 5.3 2.9 3 0 0 3 3 3 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit NAD_binding_1 PF00175.16 KFX90148.1 - 0.091 13.3 0.0 0.18 12.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain DUF373 PF04123.8 KFX90148.1 - 7.1 5.5 7.9 1.9 7.3 1.3 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF373) FGGY_C PF02782.11 KFX90149.1 - 8.3e-27 94.0 0.0 1.5e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KFX90149.1 - 3.9e-24 85.2 0.0 3.1e-15 56.1 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain AhpC-TSA_2 PF13911.1 KFX90151.1 - 5.2e-11 42.4 0.0 7.6e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KFX90151.1 - 2.9e-05 23.7 0.0 4.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KFX90151.1 - 0.12 11.9 0.0 0.45 10.0 0.0 1.9 1 1 0 1 1 1 0 Redoxin Pkinase PF00069.20 KFX90152.1 - 5.8e-69 232.1 0.0 7.9e-69 231.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX90152.1 - 1.8e-50 171.4 0.0 2.7e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX90152.1 - 0.00018 20.5 0.0 0.014 14.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like FAD_binding_2 PF00890.19 KFX90158.1 - 1e-82 278.2 0.1 1.7e-82 277.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 KFX90158.1 - 4.2e-21 74.5 0.5 6.6e-20 70.6 0.0 2.7 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 KFX90158.1 - 1.2e-12 47.4 0.7 2.6e-11 43.0 0.5 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KFX90158.1 - 1.1e-09 37.9 0.1 3e-09 36.4 0.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX90158.1 - 5.6e-08 32.6 2.0 2.6e-07 30.5 0.3 2.8 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFX90158.1 - 8.5e-08 32.3 0.0 0.0039 17.0 0.1 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFX90158.1 - 1.5e-05 24.2 0.4 0.0058 15.7 0.1 2.7 3 0 0 3 3 3 2 Thi4 family HI0933_like PF03486.9 KFX90158.1 - 0.00032 19.2 4.5 0.0092 14.4 0.1 3.2 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.17 KFX90158.1 - 0.0018 17.2 1.8 0.21 10.3 0.5 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.19 KFX90158.1 - 0.0038 16.3 0.2 0.34 9.9 0.0 2.4 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KFX90158.1 - 0.013 15.5 0.8 0.039 13.9 0.5 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFX90158.1 - 0.016 14.2 0.7 0.049 12.6 0.2 1.8 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 KFX90158.1 - 0.019 14.7 0.1 0.11 12.2 0.0 2.3 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 KFX90158.1 - 0.15 12.4 3.8 2 8.8 0.4 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_60s PF00428.14 KFX90158.1 - 6.9 7.1 10.9 16 5.9 7.5 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Fasciclin PF02469.17 KFX90159.1 - 2.7e-05 24.1 0.0 5.2e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Fasciclin domain PAH PF02671.16 KFX90160.1 - 1.2e-44 149.6 8.4 7e-18 63.9 0.2 4.0 4 0 0 4 4 4 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 KFX90160.1 - 2.3e-37 126.7 0.0 8e-37 125.0 0.0 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor Haemolytic PF01809.13 KFX90160.1 - 0.25 10.9 0.1 0.58 9.8 0.1 1.5 1 0 0 1 1 1 0 Haemolytic domain Suf PF05843.9 KFX90162.1 - 1.5 8.4 3.9 2.3 7.8 2.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CAF1A PF12253.3 KFX90163.1 - 2.4e-23 82.0 3.5 2.4e-23 82.0 2.4 3.0 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 KFX90163.1 - 2.8e-14 53.0 44.9 2.8e-14 53.0 31.1 1.8 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal MIP-T3 PF10243.4 KFX90163.1 - 0.0011 17.5 33.8 0.0018 16.8 23.4 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 LMBR1 PF04791.11 KFX90163.1 - 0.085 11.4 7.9 0.11 11.0 5.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SAPS PF04499.10 KFX90163.1 - 0.12 10.9 7.9 0.16 10.6 5.5 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Borrelia_P83 PF05262.6 KFX90163.1 - 1.4 7.1 39.1 2.2 6.4 27.1 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein IncA PF04156.9 KFX90163.1 - 3.6 7.1 22.4 0.22 11.0 11.4 1.9 2 0 0 2 2 2 0 IncA protein DUF2418 PF10332.4 KFX90166.1 - 5.9e-30 103.4 0.0 1.2e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) TFIIA PF03153.8 KFX90166.1 - 5.2 6.8 8.0 6.9 6.4 5.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aconitase PF00330.15 KFX90167.1 - 1.9e-179 597.0 0.1 4.3e-179 595.8 0.1 1.5 2 0 0 2 2 2 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KFX90167.1 - 1.1e-44 151.6 0.0 2e-44 150.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain RabGAP-TBC PF00566.13 KFX90168.1 - 1.5e-34 119.3 1.7 3e-34 118.3 1.2 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF2247 PF10004.4 KFX90168.1 - 0.018 14.7 0.2 0.032 13.9 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) HD_3 PF13023.1 KFX90168.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 HD domain CBM_1 PF00734.13 KFX90173.1 - 9.4e-07 28.3 9.7 2.5e-06 27.0 6.7 1.8 1 1 0 1 1 1 1 Fungal cellulose binding domain Conotoxin PF02950.12 KFX90173.1 - 0.051 14.3 0.9 0.064 14.0 0.7 1.3 1 0 0 1 1 1 0 Conotoxin Ubiquitin_3 PF14836.1 KFX90174.1 - 0.2 11.3 1.1 0.37 10.4 0.8 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Pkinase PF00069.20 KFX90176.1 - 6.5e-13 48.4 0.0 8.3e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KFX90176.1 - 8e-06 25.7 0.2 1.3e-05 25.0 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KFX90176.1 - 0.0001 21.5 0.0 0.00014 21.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFX90176.1 - 0.00059 18.9 0.0 0.00085 18.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFX90176.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 KFX90176.1 - 0.12 11.9 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF3661 PF12400.3 KFX90182.1 - 5.3e-42 142.9 4.4 6.6e-42 142.6 3.1 1.1 1 0 0 1 1 1 1 Vaculolar membrane protein Methyltransf_23 PF13489.1 KFX90186.1 - 8.5e-18 64.5 0.0 1.5e-17 63.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX90186.1 - 4.3e-17 62.3 0.0 7.4e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX90186.1 - 5.5e-15 55.2 0.0 7.4e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX90186.1 - 2.7e-14 53.4 0.0 5.3e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX90186.1 - 9.2e-14 51.9 0.0 1.4e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KFX90186.1 - 3.7e-07 29.1 0.0 5.3e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_26 PF13659.1 KFX90186.1 - 4.3e-07 29.9 0.0 3.2e-06 27.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX90186.1 - 1.1e-06 28.9 0.0 2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFX90186.1 - 1.9e-06 27.2 0.0 2.5e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KFX90186.1 - 2.4e-05 23.5 0.0 3.3e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 KFX90186.1 - 0.00038 19.9 0.0 0.00055 19.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.15 KFX90186.1 - 0.00063 18.9 0.0 0.0017 17.4 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 KFX90186.1 - 0.0024 17.2 0.0 0.0043 16.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 KFX90186.1 - 0.031 13.1 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase FtsJ PF01728.14 KFX90186.1 - 0.1 12.5 0.1 0.77 9.7 0.0 2.2 2 1 0 2 2 2 0 FtsJ-like methyltransferase DHBP_synthase PF00926.14 KFX90187.1 - 1.5e-69 233.1 0.0 4.7e-69 231.5 0.0 1.6 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Sec3_C PF09763.4 KFX90188.1 - 1.7e-209 697.5 5.1 2.3e-209 697.0 3.6 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 p450 PF00067.17 KFX90188.1 - 4.7e-39 134.1 0.0 1.2e-38 132.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome P450 Sec3-PIP2_bind PF15277.1 KFX90188.1 - 7.1e-30 102.7 0.0 1.6e-29 101.6 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 KFX90188.1 - 0.039 14.0 0.0 0.13 12.3 0.0 1.9 1 0 0 1 1 1 0 Sec3 exocyst complex subunit SRP40_C PF05022.7 KFX90189.1 - 4.2e-24 84.8 0.7 4.2e-24 84.8 0.5 2.6 4 0 0 4 4 4 1 SRP40, C-terminal domain DUF755 PF05501.6 KFX90189.1 - 0.0053 16.7 3.8 0.0053 16.7 2.7 7.8 2 1 5 7 7 7 2 Domain of unknown function (DUF755) A_deaminase PF00962.17 KFX90190.1 - 3.4e-46 157.7 0.0 4.5e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 KFX90190.1 - 0.017 15.1 0.0 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 Adenosine/AMP deaminase N-terminal FCP1_C PF09309.5 KFX90194.1 - 0.0032 16.8 3.2 0.0052 16.1 2.2 1.3 1 0 0 1 1 1 1 FCP1, C-terminal MIF4G PF02854.14 KFX90195.1 - 5.7e-63 212.0 0.1 2.7e-28 98.8 0.0 3.5 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 KFX90195.1 - 5e-56 189.1 10.7 5e-56 189.1 7.4 3.3 4 0 0 4 4 4 1 Up-frameshift suppressor 2 UvdE PF03851.9 KFX90199.1 - 8e-108 359.6 0.0 9.9e-108 359.3 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF1664 PF07889.7 KFX90200.1 - 1.9 8.3 6.4 2.6 7.8 0.3 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Sec1 PF00995.18 KFX90245.1 - 1.3e-123 413.6 0.1 1.6e-123 413.3 0.1 1.1 1 0 0 1 1 1 1 Sec1 family HAD_2 PF13419.1 KFX90247.1 - 3.6e-17 63.1 0.0 5e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFX90247.1 - 2.4e-08 33.5 0.0 4.6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KFX90247.1 - 1.3e-06 28.9 0.0 6.6e-06 26.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.13 KFX90247.1 - 0.061 12.9 0.0 4 7.0 0.3 2.3 1 1 0 2 2 2 0 NLI interacting factor-like phosphatase Pterin_bind PF00809.17 KFX90247.1 - 0.1 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Pterin binding enzyme GFO_IDH_MocA PF01408.17 KFX90248.1 - 1.5e-11 44.8 0.3 4.5e-11 43.3 0.2 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DHDPS PF00701.17 KFX90249.1 - 1.4e-35 122.3 0.0 1.6e-35 122.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Pkinase PF00069.20 KFX90260.1 - 4.7e-58 196.3 0.0 7.2e-58 195.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX90260.1 - 5.1e-21 74.9 0.0 3.4e-20 72.2 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase RRF_GI PF12614.3 KFX90262.1 - 1.7 8.5 6.5 2 8.2 0.5 2.3 2 0 0 2 2 2 0 Ribosome recycling factor TPR_11 PF13414.1 KFX90263.1 - 1.6e-35 120.5 25.0 2.3e-10 39.9 2.5 7.3 5 2 2 7 7 7 7 TPR repeat TPR_1 PF00515.23 KFX90263.1 - 9.1e-31 104.1 20.6 4.1e-07 29.3 0.1 8.2 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 KFX90263.1 - 1.8e-28 96.1 31.3 1.9e-05 24.2 0.1 9.6 11 0 0 11 11 10 7 Tetratricopeptide repeat Apc3 PF12895.2 KFX90263.1 - 1.9e-26 91.9 19.9 1.6e-19 69.7 0.6 5.0 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KFX90263.1 - 8.4e-22 76.9 22.8 1.6e-06 27.9 0.5 7.7 6 2 1 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 KFX90263.1 - 4.5e-20 69.8 8.9 0.00019 20.9 0.2 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 KFX90263.1 - 6.2e-17 61.7 25.3 4.6e-07 30.3 1.0 7.8 5 3 2 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFX90263.1 - 9.5e-17 61.1 10.5 0.00034 20.8 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFX90263.1 - 3e-14 52.2 13.0 0.27 11.9 0.1 9.3 6 2 4 10 10 10 5 Tetratricopeptide repeat TPR_17 PF13431.1 KFX90263.1 - 6.9e-14 50.8 13.1 0.74 10.1 0.0 9.8 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFX90263.1 - 4e-13 48.0 10.7 0.0077 15.9 0.0 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 KFX90263.1 - 4.1e-08 33.1 14.8 2.1 9.0 0.5 8.5 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_20 PF14561.1 KFX90263.1 - 0.0031 17.5 4.0 12 6.1 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 KFX90263.1 - 0.092 12.6 10.3 23 4.9 0.0 5.5 6 1 0 6 6 6 0 Tetratricopeptide repeat DUF788 PF05620.6 KFX90264.1 - 1.5e-43 148.6 0.0 1.6e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Histone PF00125.19 KFX90265.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KFX90265.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 KFX90265.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KFX90265.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KFX90265.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KFX90265.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CTK3 PF12243.3 KFX90266.1 - 4.8e-54 181.7 0.4 6.7e-54 181.2 0.2 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 KFX90266.1 - 3.2e-19 68.7 4.7 7.2e-19 67.5 3.3 1.6 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus MAM33 PF02330.11 KFX90266.1 - 0.0063 16.3 0.1 0.011 15.5 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial glycoprotein Gasdermin PF04598.7 KFX90266.1 - 0.096 11.4 0.1 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Gasdermin family P5CR_dimer PF14748.1 KFX90267.1 - 1.4e-33 115.1 0.4 3.9e-33 113.6 0.3 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KFX90267.1 - 5e-10 39.6 0.2 8.5e-09 35.7 0.0 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent CAP160 PF07918.6 KFX90267.1 - 0.016 14.8 0.4 0.038 13.6 0.3 1.6 1 0 0 1 1 1 0 CAP160 repeat Hat1_N PF10394.4 KFX90268.1 - 1.7e-41 141.9 0.0 3.7e-41 140.8 0.0 1.6 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus MFS_1 PF07690.11 KFX90292.1 - 2.4e-40 138.3 25.7 3.3e-40 137.9 17.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFX90292.1 - 2e-09 36.3 15.1 5.9e-06 24.9 2.3 2.6 1 1 1 2 2 2 2 MFS/sugar transport protein BT1 PF03092.11 KFX90292.1 - 0.00017 20.4 0.9 0.041 12.5 0.0 2.3 2 1 0 2 2 2 2 BT1 family MFS_3 PF05977.8 KFX90292.1 - 0.0016 16.6 19.1 0.0037 15.4 2.1 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector YIF1 PF03878.10 KFX90292.1 - 0.43 9.7 3.2 0.25 10.4 0.5 1.8 2 0 0 2 2 2 0 YIF1 OATP PF03137.15 KFX90292.1 - 0.52 8.2 6.0 1.1 7.2 2.0 2.4 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ADH_zinc_N PF00107.21 KFX90294.1 - 2.5e-26 91.7 0.1 3.7e-26 91.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX90294.1 - 5.4e-12 46.7 0.0 6.7e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2236 PF09995.4 KFX90294.1 - 0.084 12.1 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) DUF1769 PF08588.5 KFX90295.1 - 7.1e-25 86.7 0.2 1.5e-24 85.7 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Coat_X PF07552.6 KFX90295.1 - 0.058 13.1 2.1 2.8 7.7 0.2 2.3 2 0 0 2 2 2 0 Spore Coat Protein X and V domain DUF4568 PF15132.1 KFX90295.1 - 0.078 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) DUF3506 PF12014.3 KFX90296.1 - 3.2e-49 166.2 0.0 2.4e-48 163.3 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 KFX90296.1 - 0.00013 21.6 0.2 0.00022 20.8 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX90296.1 - 0.00064 19.3 0.6 0.0011 18.5 0.4 1.4 1 0 0 1 1 1 1 F-box domain 7TM_GPCR_Srv PF10323.4 KFX90297.1 - 0.046 12.8 0.0 0.053 12.6 0.0 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Shisa PF13908.1 KFX90297.1 - 0.056 13.6 0.0 0.056 13.6 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TRAP-gamma PF07074.7 KFX90297.1 - 0.081 12.4 0.0 0.09 12.2 0.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) DUF4446 PF14584.1 KFX90297.1 - 0.081 12.7 0.0 0.091 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF3408 PF11888.3 KFX90299.1 - 0.036 14.0 0.0 0.041 13.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) CNH PF00780.17 KFX90304.1 - 6.6e-73 245.5 0.0 9.8e-73 244.9 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 KFX90304.1 - 1.8e-27 96.3 0.7 3.6e-27 95.3 0.5 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 KFX90304.1 - 5.4e-14 52.2 0.1 3.7e-13 49.5 0.1 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KFX90304.1 - 5.4e-05 23.3 0.0 0.00021 21.4 0.0 2.1 2 0 0 2 2 2 1 PH domain Mid2 PF04478.7 KFX90306.1 - 8.7e-06 25.2 1.5 8.7e-06 25.2 1.1 2.4 1 1 2 3 3 3 1 Mid2 like cell wall stress sensor Ndc1_Nup PF09531.5 KFX90306.1 - 0.027 12.8 4.3 0.037 12.4 3.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SKG6 PF08693.5 KFX90306.1 - 0.097 12.0 0.2 0.097 12.0 0.1 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain PAP1 PF08601.5 KFX90306.1 - 0.18 11.4 19.0 0.24 11.0 13.2 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 FixQ PF05545.6 KFX90306.1 - 0.24 11.0 1.9 0.44 10.2 1.3 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Macoilin PF09726.4 KFX90306.1 - 0.75 7.9 9.6 1.1 7.5 6.7 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF972 PF06156.8 KFX90307.1 - 0.083 13.2 0.6 0.17 12.2 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 KFX90307.1 - 3.4 7.2 5.6 6.3 6.3 3.8 1.4 1 0 0 1 1 1 0 Septum formation initiator rRNA_processing PF08524.6 KFX90312.1 - 0.0029 17.4 9.3 0.0035 17.1 6.4 1.1 1 0 0 1 1 1 1 rRNA processing Enkurin PF13864.1 KFX90312.1 - 0.05 13.8 4.2 0.062 13.5 2.9 1.3 1 0 0 1 1 1 0 Calmodulin-binding Spc7_N PF15402.1 KFX90312.1 - 0.7 7.8 11.0 0.68 7.8 7.6 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Mnd1 PF03962.10 KFX90312.1 - 1.7 8.2 5.8 2 8.0 4.0 1.1 1 0 0 1 1 1 0 Mnd1 family DUF4337 PF14235.1 KFX90312.1 - 4.8 7.0 5.7 5.8 6.7 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) U79_P34 PF03064.11 KFX90312.1 - 4.8 6.6 10.6 5.5 6.4 7.3 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CBM_1 PF00734.13 KFX90313.1 - 5.8e-09 35.4 1.8 5.8e-09 35.4 1.2 2.5 3 0 0 3 3 3 1 Fungal cellulose binding domain zf-C2H2 PF00096.21 KFX90319.1 - 0.00077 19.6 2.8 0.022 15.0 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX90319.1 - 0.0013 18.8 1.6 0.057 13.7 0.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFX90319.1 - 0.15 12.2 1.8 8.6 6.6 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Malic_M PF03949.10 KFX90320.1 - 5.7e-85 284.9 0.0 7.9e-85 284.4 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KFX90320.1 - 3.1e-63 212.6 0.0 4.7e-63 212.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF187 PF02638.10 KFX90320.1 - 0.0012 17.7 0.1 0.32 9.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase like GH101 HTH_6 PF01418.12 KFX90321.1 - 0.13 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family HTH_23 PF13384.1 KFX90321.1 - 0.15 11.7 0.2 0.48 10.1 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain Zn_clus PF00172.13 KFX90322.1 - 0.00011 22.0 10.4 0.00017 21.3 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain INSIG PF07281.7 KFX90342.1 - 3e-47 160.4 1.6 3.8e-47 160.1 1.1 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) N-SET PF11764.3 KFX90343.1 - 1e-38 132.8 0.5 1e-38 132.8 0.3 2.3 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 KFX90343.1 - 3.2e-22 79.5 0.1 3.2e-22 79.5 0.1 3.5 2 2 0 2 2 2 1 SET domain SET_assoc PF11767.3 KFX90343.1 - 1.4e-17 62.7 0.0 2.8e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated Nup35_RRM_2 PF14605.1 KFX90343.1 - 0.13 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif EF-hand_4 PF12763.2 KFX90344.1 - 2.8e-34 116.9 0.0 1.6e-14 53.5 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 KFX90344.1 - 2.8e-10 40.1 0.0 0.0002 21.4 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain pair IncA PF04156.9 KFX90344.1 - 2.8e-09 36.8 25.1 7.3e-08 32.2 3.8 2.2 1 1 1 2 2 2 2 IncA protein EF-hand_1 PF00036.27 KFX90344.1 - 3.5e-07 29.0 0.0 0.088 12.1 0.0 4.8 5 0 0 5 5 5 1 EF hand EF-hand_6 PF13405.1 KFX90344.1 - 0.00014 21.4 0.0 3.5 7.7 0.0 4.5 5 0 0 5 5 4 1 EF-hand domain Macoilin PF09726.4 KFX90344.1 - 0.0004 18.8 18.4 0.00075 17.9 12.7 1.4 1 0 0 1 1 1 1 Transmembrane protein CCDC144C PF14915.1 KFX90344.1 - 0.00078 18.4 25.4 0.0015 17.5 17.6 1.4 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region EF-hand_8 PF13833.1 KFX90344.1 - 0.012 15.2 0.0 4.7 6.9 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain pair MAD PF05557.8 KFX90344.1 - 0.013 13.6 22.4 0.019 13.1 15.5 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Reo_sigmaC PF04582.7 KFX90344.1 - 0.028 13.6 13.3 0.012 14.8 3.9 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein GOLGA2L5 PF15070.1 KFX90344.1 - 0.037 12.5 21.9 0.057 11.9 15.1 1.2 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 EzrA PF06160.7 KFX90344.1 - 0.065 11.3 18.7 0.098 10.8 13.0 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.4 KFX90344.1 - 0.084 12.7 32.4 0.1 12.4 13.1 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MbeD_MobD PF04899.7 KFX90344.1 - 0.19 11.6 17.5 1.1 9.2 0.7 3.5 1 1 2 3 3 3 0 MbeD/MobD like DUF3584 PF12128.3 KFX90344.1 - 0.2 8.9 31.8 0.29 8.4 22.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TPR_MLP1_2 PF07926.7 KFX90344.1 - 0.32 10.7 33.9 1.4 8.6 13.3 2.7 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.6 KFX90344.1 - 0.37 10.5 33.5 0.97 9.2 18.2 2.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.7 KFX90344.1 - 0.46 10.2 10.6 0.13 12.0 3.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 KFX90344.1 - 0.49 9.0 29.7 0.052 12.2 5.3 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein GP41 PF00517.12 KFX90344.1 - 0.6 9.6 11.6 1.6 8.2 0.9 2.2 2 0 0 2 2 2 0 Retroviral envelope protein Tnp_P_element PF12017.3 KFX90344.1 - 0.89 8.7 7.4 0.12 11.6 2.1 1.7 1 1 0 1 1 1 0 Transposase protein FliJ PF02050.11 KFX90344.1 - 1.7 8.7 31.1 1 9.4 9.9 2.7 1 1 2 3 3 3 0 Flagellar FliJ protein CENP-Q PF13094.1 KFX90344.1 - 1.7 8.6 36.8 5.7 6.9 9.1 2.4 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit TMF_TATA_bd PF12325.3 KFX90344.1 - 2 8.1 24.4 0.2 11.3 3.0 3.1 1 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.5 KFX90344.1 - 2.4 8.3 21.6 0.1 12.7 6.0 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2730 PF10805.3 KFX90344.1 - 3.5 7.4 11.1 6.5 6.5 3.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) COG2 PF06148.6 KFX90344.1 - 4.3 7.2 16.5 0.23 11.2 3.5 2.6 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Atg14 PF10186.4 KFX90344.1 - 4.4 6.1 33.7 10 4.9 10.1 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF812 PF05667.6 KFX90344.1 - 4.7 5.6 29.2 2.4 6.5 17.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF2968 PF11180.3 KFX90344.1 - 4.9 6.4 30.3 2.9 7.2 10.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Allexi_40kDa PF05549.6 KFX90344.1 - 5 6.3 18.1 2.9 7.1 2.4 2.5 1 1 1 2 2 2 0 Allexivirus 40kDa protein Cortex-I_coil PF09304.5 KFX90344.1 - 5.2 7.1 26.5 0.86 9.6 7.1 2.8 1 1 2 3 3 3 0 Cortexillin I, coiled coil Rab5-bind PF09311.6 KFX90344.1 - 5.3 6.8 37.6 4 7.3 5.4 2.2 1 1 1 2 2 2 0 Rabaptin-like protein APG6 PF04111.7 KFX90344.1 - 5.5 5.9 30.6 1 8.3 11.5 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Cep57_MT_bd PF06657.8 KFX90344.1 - 6.5 6.7 14.1 0.077 12.9 2.3 3.1 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 AAA_13 PF13166.1 KFX90344.1 - 8.2 4.7 23.5 14 3.9 15.6 1.6 1 1 0 1 1 1 0 AAA domain Seryl_tRNA_N PF02403.17 KFX90344.1 - 9.2 6.3 29.1 15 5.6 8.6 2.7 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Tubulin PF00091.20 KFX90345.1 - 4.8e-70 235.7 0.0 6.6e-70 235.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFX90345.1 - 1.8e-48 163.7 0.1 3.3e-48 162.9 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFX90345.1 - 0.0023 17.4 0.0 0.0051 16.2 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Pga1 PF10333.4 KFX90346.1 - 0.0069 16.0 0.0 0.012 15.3 0.0 1.5 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Fanconi_A PF03511.9 KFX90357.1 - 0.085 12.6 0.1 0.31 10.8 0.1 1.9 1 0 0 1 1 1 0 Fanconi anaemia group A protein UPF0121 PF03661.8 KFX90358.1 - 3.8e-11 42.6 1.7 5.6e-11 42.0 1.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Palm_thioest PF02089.10 KFX90359.1 - 4.3e-61 206.3 0.0 5.5e-61 205.9 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.6 KFX90359.1 - 0.0014 17.8 0.0 0.0026 16.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.13 KFX90359.1 - 0.085 12.1 0.0 0.68 9.2 0.0 2.1 1 1 0 1 1 1 0 Lipase (class 2) HTH_18 PF12833.2 KFX90359.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Cyclin_N PF00134.18 KFX90360.1 - 1.8e-10 40.4 0.5 9.6e-08 31.6 0.0 2.5 1 1 2 3 3 3 2 Cyclin, N-terminal domain UreF PF01730.11 KFX90361.1 - 5.4e-14 52.5 0.1 1.4e-13 51.2 0.1 1.7 1 0 0 1 1 1 1 UreF Cut12 PF11500.3 KFX90362.1 - 6e-37 126.6 12.2 6e-37 126.6 8.5 3.9 2 2 1 3 3 3 1 Spindle pole body formation-associated protein Ifi-6-16 PF06140.8 KFX90362.1 - 0.03 14.1 15.3 0.055 13.2 10.6 1.4 1 0 0 1 1 1 0 Interferon-induced 6-16 family UQ_con PF00179.21 KFX90363.1 - 1.3e-38 131.5 0.0 1.6e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme YL1 PF05764.8 KFX90363.1 - 4.4 6.8 14.0 6 6.3 9.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Mad3_BUB1_II PF08171.6 KFX90364.1 - 0.042 13.7 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Mad3/BUB1 homology region 2 Transaldolase PF00923.14 KFX90369.1 - 2.1e-94 315.8 0.2 2.4e-94 315.6 0.1 1.0 1 0 0 1 1 1 1 Transaldolase C5-epim_C PF06662.8 KFX90369.1 - 0.014 14.6 0.0 0.027 13.7 0.0 1.5 1 1 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus bZIP_2 PF07716.10 KFX90372.1 - 5.6e-12 45.2 9.0 1.2e-11 44.2 6.2 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KFX90372.1 - 6.2e-05 22.8 8.4 0.00012 21.9 5.7 1.6 1 1 0 1 1 1 1 bZIP transcription factor XhlA PF10779.4 KFX90372.1 - 0.013 15.3 1.0 0.027 14.3 0.7 1.5 1 0 0 1 1 1 0 Haemolysin XhlA IncA PF04156.9 KFX90372.1 - 0.065 12.8 0.7 0.099 12.2 0.5 1.3 1 0 0 1 1 1 0 IncA protein Rotamase PF00639.16 KFX90372.1 - 4.6 8.0 7.7 17 6.2 0.1 2.6 2 1 1 3 3 3 0 PPIC-type PPIASE domain ABC_membrane PF00664.18 KFX90374.1 - 5.6e-69 232.5 28.8 1.4e-35 123.0 7.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFX90374.1 - 7.3e-62 207.6 0.0 7.7e-32 110.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFX90374.1 - 4.6e-12 45.6 2.0 6.1e-05 22.3 1.1 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KFX90374.1 - 2.3e-09 38.0 0.0 0.003 18.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 KFX90374.1 - 1.1e-08 35.3 0.3 0.044 13.7 0.0 4.1 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KFX90374.1 - 1.4e-08 34.9 3.2 0.0014 18.6 0.3 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KFX90374.1 - 1.3e-07 31.0 0.2 0.0056 16.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KFX90374.1 - 6.6e-06 26.3 0.0 1 9.5 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.1 KFX90374.1 - 2.3e-05 24.7 0.1 0.23 11.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 KFX90374.1 - 2.3e-05 24.3 0.0 0.32 10.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KFX90374.1 - 3e-05 23.2 0.1 0.021 14.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF87 PF01935.12 KFX90374.1 - 3.2e-05 23.8 1.9 0.0015 18.3 0.1 2.7 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_19 PF13245.1 KFX90374.1 - 0.00016 21.3 2.6 0.7 9.6 0.0 4.0 3 0 0 3 3 3 2 Part of AAA domain AAA_25 PF13481.1 KFX90374.1 - 0.00016 21.1 0.1 0.82 9.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KFX90374.1 - 0.00025 20.8 0.6 1.5 8.7 0.1 3.3 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 KFX90374.1 - 0.00048 19.6 0.6 0.14 11.5 0.1 2.7 3 0 0 3 3 3 1 AAA-like domain AAA_23 PF13476.1 KFX90374.1 - 0.00051 20.4 0.3 0.41 10.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFX90374.1 - 0.00061 18.9 0.0 0.32 10.0 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin ABC_ATPase PF09818.4 KFX90374.1 - 0.0015 17.1 2.8 0.15 10.5 0.0 3.7 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA PF00004.24 KFX90374.1 - 0.0019 18.4 0.2 18 5.4 0.1 4.2 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 KFX90374.1 - 0.0025 17.4 0.1 0.71 9.5 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_30 PF13604.1 KFX90374.1 - 0.0034 16.9 0.2 1.4 8.4 0.0 3.7 4 0 0 4 4 4 1 AAA domain MMR_HSR1 PF01926.18 KFX90374.1 - 0.0036 17.2 0.3 1.9 8.4 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 KFX90374.1 - 0.0075 15.9 0.0 3.8 7.2 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 KFX90374.1 - 0.019 13.8 0.1 5.8 5.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain DUF3987 PF13148.1 KFX90374.1 - 0.036 12.6 0.1 0.78 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_5 PF07728.9 KFX90374.1 - 0.049 13.3 0.1 5.2 6.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KFX90374.1 - 0.19 11.6 0.0 33 4.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.1 KFX90374.1 - 0.22 10.5 0.0 0.47 9.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF3129 PF11327.3 KFX90375.1 - 1.9e-63 213.6 13.4 1.9e-63 213.6 9.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3129) AIG2 PF06094.7 KFX90376.1 - 6.2e-10 39.4 0.0 9.4e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family Esterase_phd PF10503.4 KFX90377.1 - 4.6e-18 65.2 1.2 8.1e-18 64.4 0.8 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.13 KFX90377.1 - 3.5e-13 48.9 14.3 3.5e-13 48.9 9.9 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 KFX90377.1 - 2.6e-12 46.4 1.4 4.2e-12 45.7 0.6 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFX90377.1 - 1.2e-07 31.5 0.4 2.2e-07 30.7 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX90377.1 - 0.00017 21.5 0.0 0.00054 19.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KFX90377.1 - 0.00018 20.3 0.1 0.00025 19.8 0.1 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_1 PF00561.15 KFX90377.1 - 0.029 13.9 0.0 0.052 13.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.11 KFX90378.1 - 7.8e-18 64.2 27.0 7.8e-18 64.2 18.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX90378.1 - 0.00017 20.2 7.7 0.00017 20.2 5.3 3.1 1 1 2 3 3 3 1 Sugar (and other) transporter DUF3938 PF13074.1 KFX90378.1 - 0.044 13.6 0.1 0.15 11.9 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) ArabFuran-catal PF09206.6 KFX90379.1 - 2.6e-160 532.6 22.2 3.8e-160 532.1 15.4 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 KFX90379.1 - 6.4e-63 210.7 4.1 1e-62 210.0 2.8 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) F-box PF00646.28 KFX90380.1 - 5.6e-05 22.6 1.0 0.00013 21.5 0.7 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFX90380.1 - 0.00041 20.0 0.3 0.00091 18.9 0.2 1.6 1 0 0 1 1 1 1 F-box-like APC8 PF04049.8 KFX90382.1 - 1.4e-48 164.2 0.6 1.2e-47 161.2 0.1 2.2 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 KFX90382.1 - 6.9e-21 72.9 3.2 8.4e-05 22.0 0.0 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_11 PF13414.1 KFX90382.1 - 2e-19 68.9 13.4 4.9e-06 26.1 0.0 6.8 6 1 1 7 7 7 4 TPR repeat TPR_2 PF07719.12 KFX90382.1 - 9.2e-17 59.5 20.3 0.011 15.6 0.0 9.9 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 KFX90382.1 - 1.4e-13 49.5 0.9 0.00025 20.5 0.0 6.6 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFX90382.1 - 1.5e-13 50.4 14.7 0.021 14.7 0.0 6.7 5 3 1 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 KFX90382.1 - 1.6e-13 50.0 14.7 0.024 15.2 0.0 9.3 8 2 2 10 10 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 KFX90382.1 - 2e-08 33.9 16.6 0.0016 18.2 0.2 5.9 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFX90382.1 - 8.8e-08 32.6 24.5 6.6e-05 23.4 0.1 7.0 7 2 2 9 9 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFX90382.1 - 1.2e-07 30.9 12.4 0.025 14.3 0.0 6.5 9 0 0 9 9 6 3 Tetratricopeptide repeat Apc3 PF12895.2 KFX90382.1 - 3.5e-06 27.0 5.1 0.072 13.2 0.8 5.2 4 1 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KFX90382.1 - 6e-05 22.9 0.1 3.1 8.2 0.0 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFX90382.1 - 0.00015 22.0 3.4 19 5.6 0.0 6.1 6 1 0 6 6 6 0 Tetratricopeptide repeat DUF3856 PF12968.2 KFX90382.1 - 0.00049 19.9 3.4 0.0081 15.9 0.0 3.4 4 1 0 4 4 4 1 Domain of Unknown Function (DUF3856) TPR_6 PF13174.1 KFX90382.1 - 0.0039 17.5 17.3 18 6.0 0.2 9.0 10 0 0 10 10 9 0 Tetratricopeptide repeat DUF2424 PF10340.4 KFX90382.1 - 0.22 10.1 0.0 0.36 9.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) TPR_10 PF13374.1 KFX90382.1 - 0.31 11.0 0.1 0.31 11.0 0.0 6.1 8 1 1 9 9 8 0 Tetratricopeptide repeat polyprenyl_synt PF00348.12 KFX90383.1 - 1.7e-71 240.0 0.0 2.1e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase XRCC4 PF06632.7 KFX90385.1 - 1.8e-06 27.0 16.9 4.1e-06 25.9 11.7 1.6 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 PUF PF00806.14 KFX90386.1 - 3.6e-37 123.7 1.9 8.1e-06 25.0 0.0 8.8 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat DUF2730 PF10805.3 KFX90386.1 - 0.015 15.0 0.4 0.034 13.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) RraB PF06877.6 KFX90386.1 - 0.032 14.8 0.1 0.84 10.3 0.0 2.9 3 0 0 3 3 3 0 Regulator of ribonuclease activity B DUF4355 PF14265.1 KFX90386.1 - 0.24 11.3 5.2 0.77 9.7 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) MRP-S33 PF08293.6 KFX90387.1 - 2.6e-32 110.6 0.6 3.5e-32 110.2 0.1 1.4 1 1 1 2 2 2 1 Mitochondrial ribosomal subunit S27 Ribonuclease_3 PF00636.21 KFX90388.1 - 7.2e-14 52.2 0.1 2.3e-13 50.6 0.0 1.9 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KFX90388.1 - 3.9e-10 39.7 0.0 8.4e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 KFX90388.1 - 0.074 13.6 0.0 0.074 13.6 0.0 3.2 4 1 0 4 4 4 0 Double-stranded RNA binding motif DUF4230 PF14014.1 KFX90388.1 - 0.3 10.9 4.7 0.59 9.9 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) Glyco_hydro_43 PF04616.9 KFX90389.1 - 3.4e-72 242.9 0.4 5.8e-72 242.1 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 4HBT PF03061.17 KFX90389.1 - 2.5e-08 33.9 0.1 4.9e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily DUF1945 PF09178.5 KFX90389.1 - 0.052 13.4 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1945) 4HBT_3 PF13622.1 KFX90389.1 - 0.065 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF4176 PF13780.1 KFX90389.1 - 0.91 9.2 4.9 14 5.5 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4176) Sugar_tr PF00083.19 KFX90390.1 - 1.1e-73 248.4 22.5 1.3e-73 248.1 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX90390.1 - 5.1e-26 91.2 25.4 1.4e-19 70.0 4.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFX90390.1 - 2.6e-06 25.9 2.3 2.6e-06 25.9 1.6 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) BC10 PF06726.7 KFX90391.1 - 1.5e-16 60.1 10.6 3e-16 59.1 7.3 1.5 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 DZF PF07528.9 KFX90392.1 - 0.022 14.1 2.6 0.03 13.7 0.4 2.2 1 1 1 2 2 2 0 DZF domain DUF1664 PF07889.7 KFX90392.1 - 0.22 11.3 7.5 1.7 8.4 1.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) HD PF01966.17 KFX90393.1 - 5.2e-07 29.7 2.9 1.3e-06 28.4 0.2 2.6 3 0 0 3 3 3 1 HD domain IGR PF09597.5 KFX90393.1 - 0.067 13.1 0.1 20 5.1 0.0 2.7 2 0 0 2 2 2 0 IGR protein motif Carboxyl_trans PF01039.17 KFX90394.1 - 4.1e-77 259.5 0.0 5.3e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KFX90395.1 - 4.9e-55 186.0 0.0 6.8e-55 185.6 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KFX90395.1 - 5.3e-30 103.5 0.0 9.2e-30 102.7 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KFX90395.1 - 9e-26 90.1 0.0 1.7e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KFX90395.1 - 2.2e-15 56.8 0.0 4e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KFX90395.1 - 3.9e-13 48.8 0.0 4.5e-09 35.4 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 KFX90395.1 - 4.6e-11 42.1 1.4 3.9e-10 39.2 1.0 2.4 3 0 0 3 3 3 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 KFX90395.1 - 5.6e-05 22.6 0.0 9.7e-05 21.8 0.0 1.4 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KFX90395.1 - 0.00024 20.5 0.0 0.00051 19.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KFX90395.1 - 0.0015 18.4 0.0 0.0044 16.9 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain DUF2118 PF09891.4 KFX90395.1 - 0.0035 17.0 0.1 0.0068 16.1 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) RimK PF08443.6 KFX90395.1 - 0.0069 15.8 0.0 0.03 13.7 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain HlyD_2 PF12700.2 KFX90395.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 KFX90395.1 - 0.032 13.9 0.1 0.068 12.8 0.1 1.5 1 0 0 1 1 1 0 Biotin-lipoyl like RnfC_N PF13375.1 KFX90395.1 - 0.036 13.7 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain ATPgrasp_ST PF14397.1 KFX90395.1 - 0.27 10.2 0.0 0.48 9.4 0.0 1.4 1 1 0 1 1 1 0 Sugar-transfer associated ATP-grasp PDEase_I PF00233.14 KFX90397.1 - 2.9e-46 158.1 5.9 1.6e-40 139.3 0.0 3.1 3 0 0 3 3 3 3 3'5'-cyclic nucleotide phosphodiesterase ClpS PF02617.12 KFX90397.1 - 0.00066 19.3 0.4 1.2 8.8 0.0 2.5 2 0 0 2 2 2 2 ATP-dependent Clp protease adaptor protein ClpS DUF3535 PF12054.3 KFX90403.1 - 1.4e-143 478.6 4.9 8.6e-143 476.1 2.4 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 KFX90403.1 - 4.4e-72 242.4 0.0 6.4e-72 241.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 KFX90403.1 - 3.2e-18 64.0 10.6 0.05 13.6 0.0 10.3 9 0 0 9 9 9 6 HEAT repeat Helicase_C PF00271.26 KFX90403.1 - 4.3e-15 55.3 0.0 9e-15 54.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.2 KFX90403.1 - 1.2e-07 32.0 0.2 0.23 11.8 0.0 4.1 2 1 1 3 3 3 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 KFX90403.1 - 5.1e-05 22.7 0.0 0.069 12.4 0.0 3.5 2 1 2 4 4 4 2 CLASP N terminal HEAT_EZ PF13513.1 KFX90403.1 - 0.0034 17.8 16.6 30 5.2 0.0 9.1 9 0 0 9 9 9 0 HEAT-like repeat Fungal_trans PF04082.13 KFX90405.1 - 4.5e-18 65.0 0.0 8.8e-18 64.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX90405.1 - 0.00024 20.9 8.6 0.00048 19.9 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SurE PF01975.12 KFX90410.1 - 1.1e-42 145.5 0.0 1.7e-42 144.9 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE TTL PF03133.10 KFX90410.1 - 1.6e-27 96.2 0.0 2.4e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 KFX90410.1 - 0.017 14.8 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain CrtC PF07143.6 KFX90418.1 - 9.9e-17 61.1 0.8 2.6e-11 43.3 0.0 2.1 2 0 0 2 2 2 2 Hydroxyneurosporene synthase (CrtC) DUF3425 PF11905.3 KFX90419.1 - 1.8e-17 63.4 0.3 3.5e-17 62.5 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KFX90419.1 - 0.025 14.5 5.4 0.041 13.8 3.8 1.3 1 0 0 1 1 1 0 bZIP transcription factor NmrA PF05368.8 KFX90420.1 - 1.1e-33 116.4 0.0 1.5e-32 112.7 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX90420.1 - 4.8e-08 33.2 0.1 7.5e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFX90420.1 - 0.00033 19.4 0.0 0.0005 18.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KFX90420.1 - 0.00043 20.2 0.0 0.00091 19.2 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 KFX90420.1 - 0.0016 18.3 0.1 0.0025 17.7 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KFX90420.1 - 0.0037 16.7 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KFX90420.1 - 0.0063 16.8 0.0 0.018 15.3 0.0 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3-dmu-9_3-mt PF06983.8 KFX90421.1 - 4.8e-45 152.6 0.3 6.4e-45 152.2 0.2 1.2 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase Glyoxalase PF00903.20 KFX90421.1 - 0.0045 16.9 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily zinc_ribbon_2 PF13240.1 KFX90422.1 - 0.1 12.1 0.3 0.21 11.1 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain RasGAP_C PF03836.10 KFX90422.1 - 0.58 9.8 8.3 0.4 10.3 0.3 2.5 2 0 0 2 2 2 0 RasGAP C-terminus IFT20 PF14931.1 KFX90422.1 - 0.8 9.6 6.7 1.9 8.4 0.7 3.3 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 DUF1691 PF07950.6 KFX90424.1 - 1.7e-19 69.8 0.4 7.7e-14 51.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) zf-C2H2_jaz PF12171.3 KFX90425.1 - 0.00043 20.3 1.2 0.00076 19.5 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFX90425.1 - 0.0038 17.3 0.1 0.0065 16.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 KFX90425.1 - 0.014 15.0 1.0 0.025 14.2 0.7 1.3 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2 PF00096.21 KFX90425.1 - 0.028 14.7 0.5 0.048 14.0 0.4 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3449 PF11931.3 KFX90425.1 - 0.065 12.7 1.1 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) zf-C2H2_4 PF13894.1 KFX90425.1 - 0.12 12.8 0.1 0.22 11.9 0.1 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger MFS_1 PF07690.11 KFX90426.1 - 4.3e-34 117.7 50.6 4.3e-34 117.7 35.1 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sucrose_synth PF00862.14 KFX90427.1 - 0.0089 14.0 0.3 0.012 13.6 0.2 1.1 1 0 0 1 1 1 1 Sucrose synthase EcoEI_R_C PF08463.5 KFX90427.1 - 0.036 13.9 6.1 0.19 11.5 0.6 2.2 1 1 1 2 2 2 0 EcoEI R protein C-terminal TPR_MLP1_2 PF07926.7 KFX90427.1 - 0.075 12.7 16.7 0.076 12.7 1.8 2.9 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein HALZ PF02183.13 KFX90427.1 - 0.46 10.2 7.5 10 5.9 0.2 3.5 2 1 1 3 3 3 0 Homeobox associated leucine zipper Arc_PepC PF06819.6 KFX90427.1 - 0.49 10.3 3.4 0.78 9.6 0.3 2.5 2 1 1 3 3 3 0 Archaeal Peptidase A24 C-terminal Domain Fez1 PF06818.10 KFX90427.1 - 0.78 9.7 20.6 0.77 9.7 4.8 2.2 1 1 1 2 2 2 0 Fez1 DUF4407 PF14362.1 KFX90427.1 - 0.89 8.4 6.1 1.5 7.6 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF904 PF06005.7 KFX90427.1 - 0.97 9.7 16.9 11 6.4 1.2 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF904) DUF4140 PF13600.1 KFX90427.1 - 6.3 7.3 13.1 5.3 7.5 0.6 3.2 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF4050 PF13259.1 KFX90434.1 - 3.2e-25 88.4 0.0 4e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) RMF PF04957.7 KFX90434.1 - 0.085 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Ribosome modulation factor Spike_rec_bind PF09408.5 KFX90434.1 - 0.15 11.5 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Spike receptor binding domain AAA PF00004.24 KFX90435.1 - 2.6e-39 134.4 0.0 1.1e-38 132.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFX90435.1 - 6.7e-06 25.3 0.3 0.00013 21.0 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 KFX90435.1 - 7.8e-06 24.8 0.2 0.00026 19.8 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus ABC_tran PF00005.22 KFX90435.1 - 2e-05 24.9 0.1 0.19 12.0 0.0 3.9 4 0 0 4 4 4 1 ABC transporter AAA_22 PF13401.1 KFX90435.1 - 2.5e-05 24.4 0.3 0.00088 19.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KFX90435.1 - 3.6e-05 23.7 0.0 0.00035 20.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KFX90435.1 - 6.9e-05 22.3 0.0 0.0036 16.7 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.1 KFX90435.1 - 0.00011 22.5 0.2 0.0025 18.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KFX90435.1 - 0.00017 22.4 0.8 0.00073 20.3 0.1 2.5 2 1 0 2 2 1 1 AAA domain AAA_2 PF07724.9 KFX90435.1 - 0.00021 21.2 0.0 0.0062 16.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KFX90435.1 - 0.00023 21.0 0.0 0.0015 18.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KFX90435.1 - 0.00026 20.7 0.0 0.00083 19.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFX90435.1 - 0.00034 20.6 1.0 0.0075 16.2 0.0 3.4 2 1 3 5 5 4 1 AAA ATPase domain AAA_14 PF13173.1 KFX90435.1 - 0.00047 20.0 0.0 0.003 17.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KFX90435.1 - 0.00071 18.8 0.0 0.004 16.3 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KFX90435.1 - 0.0022 18.1 0.0 0.012 15.8 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.1 KFX90435.1 - 0.0023 17.5 0.5 0.0088 15.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFX90435.1 - 0.0055 16.4 0.1 0.031 14.0 0.1 2.3 1 0 0 1 1 1 1 Part of AAA domain Parvo_NS1 PF01057.12 KFX90435.1 - 0.0085 14.9 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 NACHT PF05729.7 KFX90435.1 - 0.0086 15.7 0.1 0.089 12.4 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.1 KFX90435.1 - 0.0088 15.4 0.2 0.036 13.4 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_10 PF12846.2 KFX90435.1 - 0.0088 15.5 0.1 6.1 6.1 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain Sigma54_activ_2 PF14532.1 KFX90435.1 - 0.013 15.5 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 KFX90435.1 - 0.023 14.2 0.1 0.74 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 KFX90435.1 - 0.062 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) zf-AN1 PF01428.11 KFX90437.1 - 2e-11 43.5 13.9 2.9e-11 43.0 9.6 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger Glyco_hydro_18 PF00704.23 KFX90450.1 - 3.8e-70 237.0 0.0 4.6e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 zf-CCCH PF00642.19 KFX90451.1 - 2.5e-18 65.3 36.9 6.8e-07 28.8 0.5 5.4 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KFX90451.1 - 0.019 14.9 34.4 0.022 14.7 0.3 5.7 5 1 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type ADK PF00406.17 KFX90452.1 - 2.3e-14 53.5 0.0 3.1e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KFX90452.1 - 9e-11 41.2 0.0 1.7e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid Pkinase PF00069.20 KFX90457.1 - 1.3e-59 201.4 0.0 2e-59 200.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX90457.1 - 7.2e-30 103.9 0.0 1e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX90457.1 - 0.00069 18.6 0.0 0.0015 17.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFX90457.1 - 0.012 15.3 0.1 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KFX90457.1 - 0.022 13.8 0.1 0.043 12.8 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L33 PF00471.15 KFX90459.1 - 9.6e-05 22.5 0.0 0.00016 21.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L33 Reo_sigmaC PF04582.7 KFX90460.1 - 0.4 9.8 33.2 0.53 9.4 0.3 4.5 2 1 2 4 4 4 0 Reovirus sigma C capsid protein Sec8_exocyst PF04048.9 KFX90460.1 - 5.2 6.7 36.1 0.074 12.6 1.8 6.2 2 2 1 6 6 6 0 Sec8 exocyst complex component specific domain RRM_6 PF14259.1 KFX90486.1 - 2.4e-05 24.2 0.0 5.9e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFX90486.1 - 0.0011 18.5 0.0 0.0026 17.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MutS_V PF00488.16 KFX90489.1 - 1.5e-78 263.4 0.0 2.4e-78 262.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFX90489.1 - 1e-46 159.2 0.0 2.1e-46 158.3 0.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KFX90489.1 - 1.1e-32 112.4 0.3 3.5e-32 110.7 0.1 2.0 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 KFX90489.1 - 7.2e-16 58.1 0.1 1.4e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 KFX90489.1 - 6.7e-12 45.6 0.0 1.8e-11 44.2 0.0 1.7 1 1 0 1 1 1 1 MutS domain II AAA_23 PF13476.1 KFX90489.1 - 0.00061 20.1 0.2 0.0014 18.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KFX90489.1 - 0.024 14.1 0.0 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 KFX90489.1 - 0.031 14.2 0.2 0.08 12.8 0.2 1.7 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 KFX90490.1 - 2e-29 100.3 8.9 4.1e-07 29.6 0.0 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 KFX90490.1 - 1.8e-05 24.5 0.1 0.042 13.5 0.0 3.0 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.5 KFX90490.1 - 0.018 14.5 0.1 0.084 12.4 0.1 2.2 1 0 0 1 1 1 0 HIRA B motif DPPIV_N PF00930.16 KFX90490.1 - 0.022 13.3 0.0 14 4.1 0.0 3.3 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 KFX90490.1 - 0.34 10.6 6.0 3.4 7.4 0.1 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat ATP-grasp_2 PF08442.5 KFX90493.1 - 2.6e-79 265.3 0.6 4.2e-79 264.6 0.4 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 KFX90493.1 - 1e-26 93.4 0.3 2.9e-26 91.9 0.2 1.8 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KFX90493.1 - 1e-09 37.9 0.3 2.1e-09 36.9 0.2 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 KFX90493.1 - 0.00093 18.8 0.8 0.018 14.6 0.1 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 KFX90493.1 - 0.0043 16.8 0.0 0.0083 15.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ribosomal_S11 PF00411.14 KFX90493.1 - 0.01 15.9 0.1 0.66 10.1 0.0 2.8 2 0 0 2 2 2 0 Ribosomal protein S11 DUF3245 PF11595.3 KFX90494.1 - 4e-12 46.6 7.0 4e-12 46.6 4.9 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF3245) HSF_DNA-bind PF00447.12 KFX90495.1 - 3.7e-36 123.4 0.4 5.5e-36 122.8 0.3 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding F-box-like PF12937.2 KFX90497.1 - 0.03 14.0 1.1 0.043 13.5 0.1 1.8 2 0 0 2 2 2 0 F-box-like GrpB PF04229.9 KFX90498.1 - 1.7e-45 154.7 0.1 1.9e-45 154.5 0.1 1.0 1 0 0 1 1 1 1 GrpB protein Epimerase PF01370.16 KFX90499.1 - 5.1e-18 65.3 0.0 7.9e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFX90499.1 - 2.1e-12 46.5 0.0 2e-11 43.2 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KFX90499.1 - 8.8e-12 44.2 0.0 1.7e-11 43.3 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFX90499.1 - 1.1e-08 35.2 0.1 1.8e-08 34.6 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KFX90499.1 - 9e-08 32.2 0.0 1.4e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX90499.1 - 8.6e-05 22.2 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 KFX90499.1 - 0.00017 20.9 0.1 0.013 14.7 0.1 2.3 2 1 0 2 2 2 1 NmrA-like family F420_oxidored PF03807.12 KFX90499.1 - 0.0021 18.4 0.0 0.0098 16.3 0.0 2.0 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 KFX90499.1 - 0.0044 15.9 0.0 0.0063 15.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KFX90499.1 - 0.057 12.3 0.1 0.28 10.0 0.0 2.1 2 1 0 2 2 2 0 RmlD substrate binding domain bZIP_Maf PF03131.12 KFX90507.1 - 3.7e-07 30.3 10.1 3.7e-07 30.3 7.0 2.1 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.16 KFX90507.1 - 2.7e-06 27.2 10.1 2.7e-06 27.2 7.0 2.4 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KFX90507.1 - 1.2e-05 25.0 9.1 1.2e-05 25.0 6.3 2.0 2 0 0 2 2 2 1 Basic region leucine zipper BRF1 PF07741.8 KFX90508.1 - 0.32 11.2 1.1 5.7 7.2 0.2 2.7 2 1 0 3 3 3 0 Brf1-like TBP-binding domain Ribosomal_S9 PF00380.14 KFX90509.1 - 5.3e-36 123.5 0.3 7.9e-36 122.9 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.14 KFX90510.1 - 1.6e-42 143.5 0.1 3.2e-42 142.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 KFX90510.1 - 2.9e-16 59.2 0.1 7.2e-16 57.9 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFX90510.1 - 4e-13 49.0 0.0 7.8e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFX90510.1 - 6.9e-08 32.5 0.0 2.7e-07 30.6 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KFX90510.1 - 7.9e-07 29.4 0.1 1.8e-06 28.3 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFX90510.1 - 2.2e-05 24.5 0.0 5e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NIF PF03031.13 KFX90511.1 - 5.8e-16 58.5 0.0 8.9e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF947 PF06102.7 KFX90512.1 - 4.2e-52 176.3 28.5 4.2e-52 176.3 19.8 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF947) DUF2383 PF09537.5 KFX90512.1 - 0.017 15.3 8.8 0.23 11.7 2.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF2383) Es2 PF09751.4 KFX90513.1 - 1e-108 364.4 0.0 1e-108 364.4 0.0 2.1 2 0 0 2 2 2 1 Nuclear protein Es2 ABC1 PF03109.11 KFX90513.1 - 5e-33 113.6 0.0 1.2e-32 112.3 0.0 1.7 1 0 0 1 1 1 1 ABC1 family Fungal_trans_2 PF11951.3 KFX90516.1 - 3.3e-80 269.5 0.0 6.2e-50 169.8 0.0 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX90516.1 - 2e-07 30.8 10.9 3.5e-07 30.0 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HMG_CoA_synt_C PF08540.5 KFX90517.1 - 2.8e-100 335.4 0.0 3.8e-100 335.0 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFX90517.1 - 1.5e-92 307.8 0.2 2.4e-92 307.2 0.2 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Herpes_gE PF02480.11 KFX90518.1 - 0.07 11.3 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Peptidase_M7 PF02031.11 KFX90519.1 - 0.067 12.9 1.3 0.074 12.7 0.9 1.2 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family Pro_CA PF00484.14 KFX90520.1 - 6.5e-48 162.5 0.1 8.4e-48 162.2 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase PNP_UDP_1 PF01048.15 KFX90520.1 - 0.031 13.2 0.0 0.041 12.8 0.0 1.1 1 0 0 1 1 1 0 Phosphorylase superfamily TauD PF02668.11 KFX90521.1 - 9.9e-49 166.3 0.4 1.3e-48 165.9 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF427 PF04248.7 KFX90522.1 - 1.1e-26 92.3 0.9 8.6e-24 83.0 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF427) HTH_17 PF12728.2 KFX90522.1 - 0.0046 17.1 0.1 0.021 15.0 0.0 2.2 3 0 0 3 3 3 1 Helix-turn-helix domain TRP PF06011.7 KFX90523.1 - 8e-150 499.2 24.9 8e-150 499.2 17.3 1.7 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KFX90523.1 - 1.1e-37 129.2 0.4 2e-37 128.3 0.3 1.4 1 0 0 1 1 1 1 ML-like domain MFS_1 PF07690.11 KFX90523.1 - 1.1e-18 67.1 29.4 1.1e-18 67.1 20.4 3.9 3 1 0 3 3 3 1 Major Facilitator Superfamily gpUL132 PF11359.3 KFX90523.1 - 0.062 12.6 0.1 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Glycoprotein UL132 DUF843 PF05814.6 KFX90523.1 - 0.1 12.4 0.0 0.1 12.4 0.0 2.2 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) Pkinase PF00069.20 KFX90524.1 - 0.00033 19.8 0.1 0.0013 17.9 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Kei1 PF08552.6 KFX90530.1 - 1.2e-43 148.9 0.8 1.4e-43 148.7 0.6 1.0 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 SPC12 PF06645.8 KFX90530.1 - 0.47 10.2 2.5 1 9.2 1.7 1.4 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) G-patch PF01585.18 KFX90532.1 - 2e-10 40.2 0.2 2e-10 40.2 0.2 1.8 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 KFX90532.1 - 0.0015 18.3 0.1 0.0015 18.3 0.1 2.5 2 0 0 2 2 2 1 DExH-box splicing factor binding site adh_short PF00106.20 KFX90533.1 - 3.6e-14 53.0 0.0 1.1e-13 51.4 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFX90533.1 - 1e-07 31.7 0.0 4.6e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KFX90533.1 - 5.2e-06 26.0 0.0 8.3e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KFX90533.1 - 3.1e-05 23.8 0.0 8.8e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KFX90533.1 - 0.016 15.2 0.4 0.06 13.3 0.1 2.0 2 0 0 2 2 2 0 NADH(P)-binding SNF2_N PF00176.18 KFX90534.1 - 3.7e-62 209.8 0.0 6.4e-62 209.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFX90534.1 - 1.5e-10 40.7 0.0 3.4e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KFX90534.1 - 4.4e-06 26.6 6.8 4.4e-06 26.6 4.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFX90534.1 - 6.4e-06 25.9 7.8 1.7e-05 24.5 5.4 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KFX90534.1 - 1.2e-05 24.9 7.4 2.3e-05 24.0 5.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFX90534.1 - 1.4e-05 24.6 4.2 1.4e-05 24.6 2.9 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX90534.1 - 1.7e-05 24.3 7.9 3.3e-05 23.4 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFX90534.1 - 3.1e-05 23.7 7.2 6.6e-05 22.6 5.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 KFX90534.1 - 0.0014 18.4 0.6 0.003 17.3 0.4 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KFX90534.1 - 0.012 15.3 2.0 0.034 13.8 1.4 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 KFX90534.1 - 0.016 14.7 6.4 0.066 12.7 4.4 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 FYVE PF01363.16 KFX90534.1 - 0.34 10.8 3.4 1.4 8.8 2.4 2.0 1 1 0 1 1 1 0 FYVE zinc finger COesterase PF00135.23 KFX90536.1 - 2.3e-91 307.1 0.0 3e-91 306.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX90536.1 - 2e-07 30.8 0.1 3.5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX90536.1 - 0.041 13.6 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFX90536.1 - 0.05 12.8 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family RTA1 PF04479.8 KFX90537.1 - 3.1e-21 75.9 9.6 4e-21 75.5 6.7 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF1145 PF06611.7 KFX90537.1 - 0.71 9.5 3.7 1.7 8.3 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1145) Amidohydro_4 PF13147.1 KFX90538.1 - 2.1e-18 67.3 0.3 6.8e-17 62.3 0.2 2.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KFX90538.1 - 1.7e-14 54.2 0.0 1.3e-08 34.9 0.0 2.3 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 KFX90538.1 - 2.4e-10 40.2 1.8 1.2e-07 31.2 0.0 2.4 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KFX90538.1 - 3.1e-08 33.3 0.2 1.3e-07 31.3 0.2 2.1 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans_2 PF11951.3 KFX90538.1 - 9.8e-05 21.1 1.6 0.0014 17.3 0.2 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX90538.1 - 0.0026 17.6 0.7 0.005 16.7 0.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF829 PF05705.9 KFX90539.1 - 8.6e-35 120.5 0.0 1.1e-34 120.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 KFX90539.1 - 0.0013 18.6 0.1 0.0019 18.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Atg14 PF10186.4 KFX90540.1 - 0.13 11.1 8.2 0.22 10.4 5.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ribosomal_60s PF00428.14 KFX90543.1 - 3.4e-27 94.6 10.1 3.9e-27 94.4 7.0 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3138 PF11336.3 KFX90543.1 - 0.059 11.5 0.9 0.06 11.5 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CAP-ZIP_m PF15255.1 KFX90544.1 - 0.13 12.1 0.1 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 WASH complex subunit CAP-Z interacting, central region Ribosomal_S19 PF00203.16 KFX90545.1 - 1.7e-33 114.0 0.4 2.5e-33 113.5 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 SbcD_C PF12320.3 KFX90545.1 - 0.12 12.4 0.1 1.3 9.1 0.0 2.0 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Thiolase_C PF02803.13 KFX90547.1 - 0.053 12.9 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Thiolase, C-terminal domain Brevenin PF03032.10 KFX90548.1 - 0.26 11.1 0.9 0.51 10.2 0.7 1.5 1 1 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family AA_permease_2 PF13520.1 KFX90549.1 - 5.1e-50 170.2 54.5 6.2e-50 169.9 37.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFX90549.1 - 8.1e-23 80.4 44.8 1.1e-22 80.0 31.0 1.0 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_7 PF13508.1 KFX90551.1 - 9.7e-09 35.2 0.0 3.6e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX90551.1 - 1.8e-08 34.3 0.0 4.1e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFX90551.1 - 9.6e-06 25.7 0.0 1.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFX90551.1 - 8.2e-05 22.4 0.0 0.0066 16.3 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFX90551.1 - 0.022 14.6 0.0 0.068 13.0 0.0 1.8 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.5 KFX90551.1 - 0.053 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein WD40 PF00400.27 KFX90552.1 - 0.022 14.6 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 WD domain, G-beta repeat DHHA1 PF02272.14 KFX90552.1 - 0.3 10.8 1.9 0.58 9.8 0.5 2.1 2 1 1 3 3 3 0 DHHA1 domain HSP70 PF00012.15 KFX90558.1 - 7e-268 889.5 5.1 7.9e-268 889.3 3.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFX90558.1 - 4.7e-17 61.5 0.0 7.9e-16 57.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KFX90558.1 - 0.0026 17.4 0.0 0.0056 16.3 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KFX90558.1 - 0.0052 16.6 1.7 0.98 9.2 0.1 3.3 2 2 0 2 2 2 2 Cell division protein FtsA Hydantoinase_A PF01968.13 KFX90558.1 - 0.01 14.9 0.1 0.039 13.0 0.0 1.9 1 1 1 2 2 2 0 Hydantoinase/oxoprolinase StbA PF06406.6 KFX90558.1 - 0.053 12.4 0.0 0.093 11.6 0.0 1.3 1 0 0 1 1 1 0 StbA protein Mito_carr PF00153.22 KFX90562.1 - 1.6e-69 229.6 2.2 7e-24 83.3 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein CorA PF01544.13 KFX90563.1 - 0.0008 18.5 0.1 0.0014 17.7 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Mannitol_dh_C PF08125.8 KFX90565.1 - 9e-48 162.5 0.0 1.4e-47 161.9 0.0 1.3 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 KFX90565.1 - 1e-22 80.6 0.1 5.7e-22 78.2 0.0 2.2 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.9 KFX90565.1 - 0.077 12.3 0.3 0.17 11.2 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Gla PF00594.15 KFX90565.1 - 0.091 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Myb_DNA-bind_4 PF13837.1 KFX90566.1 - 8.7e-06 25.7 0.1 1.2e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 KFX90566.1 - 0.00047 20.0 0.0 0.00093 19.0 0.0 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFX90566.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.6 1 1 0 1 1 1 0 Myb-like DNA-binding domain Pex14_N PF04695.8 KFX90566.1 - 1.7 8.6 6.0 2.4 8.2 4.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4614 PF15391.1 KFX90566.1 - 7.2 6.3 8.9 9.2 5.9 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DUF2414 PF10309.4 KFX90567.1 - 3.5e-22 77.8 0.0 6.2e-22 77.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 KFX90567.1 - 0.086 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 RNA binding domain TPR_MLP1_2 PF07926.7 KFX90567.1 - 1.6 8.4 17.9 0.1 12.3 8.1 2.0 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Pec_lyase_C PF00544.14 KFX90568.1 - 1.4e-43 148.7 0.3 2.2e-43 148.0 0.2 1.3 1 0 0 1 1 1 1 Pectate lyase Beta-lactamase PF00144.19 KFX90569.1 - 6.3e-48 163.4 0.3 3.9e-47 160.8 0.1 1.9 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.3 KFX90569.1 - 1.1e-16 60.4 0.0 2e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) WW PF00397.21 KFX90576.1 - 6.1e-08 32.3 5.6 7.7e-08 32.0 3.9 1.2 1 0 0 1 1 1 1 WW domain Glyco_hydro_3 PF00933.16 KFX90587.1 - 3.2e-40 137.9 0.0 4e-40 137.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain TGS PF02824.16 KFX90588.1 - 8.9e-22 76.6 0.1 2e-21 75.5 0.1 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KFX90588.1 - 3.3e-19 68.9 0.1 8.7e-19 67.5 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFX90588.1 - 7.5e-10 38.3 0.0 4.1e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KFX90588.1 - 0.0002 20.8 2.2 1.4 8.3 0.0 4.2 3 2 1 4 4 4 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KFX90588.1 - 0.00026 20.8 0.1 0.054 13.3 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 KFX90588.1 - 0.0019 18.6 0.0 0.0068 16.8 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 KFX90588.1 - 0.0072 15.1 0.1 0.017 13.9 0.1 1.6 1 0 0 1 1 1 1 ArgK protein Arf PF00025.16 KFX90588.1 - 0.039 13.1 0.2 2.3 7.4 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Steroid_dh PF02544.11 KFX90589.1 - 6.1e-10 39.0 0.7 2.3e-09 37.1 0.0 2.2 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KFX90589.1 - 0.0099 15.1 0.3 0.018 14.3 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) 2OG-FeII_Oxy_2 PF13532.1 KFX90590.1 - 8e-13 48.6 0.0 1.2e-11 44.8 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KFX90590.1 - 2e-05 24.7 0.0 5.3e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_M3 PF01432.15 KFX90590.1 - 0.056 12.4 0.0 0.075 12.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M3 SnoaL_4 PF13577.1 KFX90600.1 - 5.2e-16 58.7 0.1 5.9e-16 58.5 0.1 1.0 1 0 0 1 1 1 1 SnoaL-like domain NAD_binding_10 PF13460.1 KFX90601.1 - 4.5e-13 49.6 0.0 5.5e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX90601.1 - 3.7e-11 42.9 0.1 1.6e-10 40.8 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KFX90601.1 - 1.3e-06 27.8 0.7 2.3e-06 27.0 0.4 1.5 2 0 0 2 2 2 1 NmrA-like family TrkA_N PF02254.13 KFX90601.1 - 1.1e-05 25.3 0.3 2.2e-05 24.4 0.1 1.6 2 0 0 2 2 2 1 TrkA-N domain F420_oxidored PF03807.12 KFX90601.1 - 0.0012 19.1 0.1 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 KFX90601.1 - 0.0021 17.9 1.3 0.0037 17.1 0.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KFX90601.1 - 0.0022 16.7 0.0 0.0034 16.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KFX90601.1 - 0.0028 17.9 0.1 0.0048 17.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 KFX90601.1 - 0.0064 15.4 0.2 0.0083 15.0 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Ldh_1_N PF00056.18 KFX90601.1 - 0.007 16.1 0.3 0.01 15.6 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KFX90601.1 - 0.011 14.6 0.1 0.026 13.4 0.1 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.21 KFX90601.1 - 0.051 13.1 0.4 0.086 12.3 0.3 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_4 PF07993.7 KFX90601.1 - 0.089 11.6 0.2 1.5 7.6 0.1 2.1 1 1 0 1 1 1 0 Male sterility protein DXP_reductoisom PF02670.11 KFX90601.1 - 0.1 13.1 0.1 0.17 12.3 0.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase KR PF08659.5 KFX90601.1 - 0.18 11.4 1.3 0.55 9.8 0.9 1.6 1 1 0 1 1 1 0 KR domain Zn_clus PF00172.13 KFX90602.1 - 0.035 14.0 10.3 0.061 13.2 7.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain NETI PF14044.1 KFX90602.1 - 0.22 11.0 0.1 0.52 9.8 0.0 1.6 1 0 0 1 1 1 0 NETI protein CybS PF05328.7 KFX90605.1 - 5.9e-49 165.0 0.0 7.9e-49 164.6 0.0 1.1 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 KFX90605.1 - 0.038 13.8 0.9 3.9 7.3 0.1 2.1 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TPPK_C PF12555.3 KFX90605.1 - 4.1 7.2 6.0 7.1 6.4 0.1 2.7 2 1 0 2 2 2 0 Thiamine pyrophosphokinase C terminal Peptidase_M16 PF00675.15 KFX90606.1 - 2.2e-57 193.0 0.1 1.3e-56 190.4 0.2 2.2 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KFX90606.1 - 7.3e-40 136.6 0.0 2.3e-39 134.9 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain MTD PF01993.13 KFX90606.1 - 0.047 12.7 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase MFS_1 PF07690.11 KFX90607.1 - 1.3e-37 129.4 58.2 7.4e-30 103.8 29.9 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Epiglycanin_C PF14654.1 KFX90607.1 - 0.026 14.5 0.6 0.22 11.5 0.0 2.7 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region DUF373 PF04123.8 KFX90607.1 - 0.12 11.3 8.8 1 8.3 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF373) Abhydrolase_4 PF08386.5 KFX90608.1 - 5.6e-22 77.5 0.0 1.1e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KFX90608.1 - 1.5e-12 47.6 0.0 5.9e-06 25.9 0.0 3.1 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFX90608.1 - 7.9e-11 42.2 2.1 4.4e-09 36.5 1.4 3.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX90608.1 - 0.0011 18.7 0.0 0.044 13.5 0.0 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Coa1 PF08695.5 KFX90611.1 - 3.5e-38 129.7 0.0 4.4e-38 129.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 RXT2_N PF08595.6 KFX90618.1 - 4.4e-40 136.8 0.2 4.4e-40 136.8 0.1 2.2 2 1 0 2 2 2 1 RXT2-like, N-terminal Chondroitinas_B PF14592.1 KFX90618.1 - 0.094 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Chondroitinase B zf-C3HC4_3 PF13920.1 KFX90621.1 - 0.0022 17.6 11.2 0.0035 16.9 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KFX90621.1 - 0.0023 17.6 6.6 0.0038 16.9 4.5 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein MIP-T3 PF10243.4 KFX90621.1 - 0.93 7.8 51.0 1.2 7.5 32.9 2.2 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 zf-RING_5 PF14634.1 KFX90621.1 - 2 8.2 12.0 3.1 7.5 8.3 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFX90621.1 - 3.8 7.6 12.7 6.2 6.9 8.8 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MSP1_C PF07462.6 KFX90621.1 - 6.8 4.9 4.1 12 4.1 2.9 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Abhydrolase_3 PF07859.8 KFX90622.1 - 2.6e-27 95.8 0.0 3.4e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KFX90622.1 - 3.6e-19 68.6 0.0 8.8e-19 67.3 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 KFX90622.1 - 0.00089 18.5 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFX90622.1 - 0.0046 16.7 0.1 0.028 14.1 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KFX90622.1 - 0.062 12.9 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal COesterase PF00135.23 KFX90622.1 - 0.12 11.0 0.3 3.5 6.2 0.1 2.0 2 0 0 2 2 2 0 Carboxylesterase family TPR_12 PF13424.1 KFX90626.1 - 6.6e-08 32.3 6.7 3.4e-07 30.1 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFX90626.1 - 6.7e-06 25.6 4.2 0.013 15.4 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFX90626.1 - 1.1e-05 25.5 3.1 0.011 16.1 0.1 3.5 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFX90626.1 - 8.9e-05 22.0 1.8 0.4 10.5 0.2 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFX90626.1 - 0.0004 19.9 5.8 0.0023 17.5 0.3 3.6 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.1 KFX90626.1 - 0.0017 18.6 2.6 0.021 15.1 0.3 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFX90626.1 - 0.019 15.1 1.7 1.4 9.3 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFX90626.1 - 0.028 14.0 6.8 0.94 9.1 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFX90626.1 - 0.034 14.8 6.0 0.094 13.4 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFX90626.1 - 0.044 13.5 1.1 3.4 7.7 0.0 3.6 4 1 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 KFX90626.1 - 0.059 13.5 1.7 0.066 13.3 0.1 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KFX90626.1 - 0.092 13.4 9.7 1.1 10.0 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.1 KFX90626.1 - 0.095 11.8 4.0 0.31 10.1 2.8 1.7 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_10 PF13374.1 KFX90626.1 - 4.8 7.2 7.5 1.6 8.7 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat ABM PF03992.11 KFX90627.1 - 0.0019 18.1 0.0 0.0056 16.6 0.0 1.8 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase CLASP_N PF12348.3 KFX90630.1 - 0.0018 17.6 0.0 0.0021 17.4 0.0 1.0 1 0 0 1 1 1 1 CLASP N terminal IBN_N PF03810.14 KFX90630.1 - 0.099 12.5 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Importin-beta N-terminal domain THF_DHG_CYH PF00763.18 KFX90635.1 - 9.5e-18 64.3 0.0 1.6e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 KFX90635.1 - 3.3e-15 55.5 0.0 2.1e-09 36.6 0.0 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ERCC4 PF02732.10 KFX90636.1 - 1.4e-19 70.2 0.0 2.8e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain DUF106 PF01956.11 KFX90637.1 - 3.3e-54 182.9 2.0 3.3e-54 182.9 1.4 1.6 1 1 1 2 2 2 1 Integral membrane protein DUF106 MscS_TM PF12794.2 KFX90637.1 - 0.0028 16.3 0.3 0.0056 15.3 0.2 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 SAPS PF04499.10 KFX90647.1 - 4.7e-124 414.6 1.1 1e-122 410.2 0.0 2.0 2 0 0 2 2 2 2 SIT4 phosphatase-associated protein Snf7 PF03357.16 KFX90649.1 - 1.7e-43 147.9 11.3 1.9e-43 147.7 7.8 1.0 1 0 0 1 1 1 1 Snf7 Reo_sigmaC PF04582.7 KFX90649.1 - 0.0087 15.2 4.0 0.11 11.6 0.4 2.0 1 1 1 2 2 2 2 Reovirus sigma C capsid protein DUF4201 PF13870.1 KFX90649.1 - 0.023 14.1 6.5 0.032 13.6 4.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Tropomyosin_1 PF12718.2 KFX90649.1 - 0.044 13.6 5.2 0.029 14.1 2.4 1.6 1 1 0 1 1 1 0 Tropomyosin like NPV_P10 PF05531.7 KFX90649.1 - 0.055 13.7 9.0 1.1 9.5 1.3 2.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1395 PF07160.7 KFX90649.1 - 0.06 12.8 4.2 0.12 11.8 1.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1395) DUF1409 PF07197.7 KFX90649.1 - 0.078 13.0 0.7 0.67 10.0 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1409) DUF342 PF03961.8 KFX90649.1 - 0.12 10.8 7.8 0.14 10.5 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) BLOC1_2 PF10046.4 KFX90649.1 - 1.5 8.9 7.8 5 7.3 2.5 2.8 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 OmpH PF03938.9 KFX90649.1 - 2.3 8.1 13.0 1.7 8.5 5.1 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) FlaC_arch PF05377.6 KFX90649.1 - 2.6 8.0 5.9 11 5.9 0.0 3.1 2 2 0 2 2 2 0 Flagella accessory protein C (FlaC) COG2 PF06148.6 KFX90649.1 - 6.9 6.5 7.5 28 4.5 2.8 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Hist_deacetyl PF00850.14 KFX90652.1 - 2e-78 263.8 0.0 3.2e-78 263.1 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain JAB PF01398.16 KFX90653.1 - 2.6e-35 120.6 0.0 5e-35 119.6 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KFX90653.1 - 3.7e-27 94.6 1.1 9.1e-27 93.4 0.8 1.7 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KFX90653.1 - 6.9e-09 35.2 0.0 1.3e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain PTR2 PF00854.16 KFX90654.1 - 1.4e-43 149.0 13.4 1.8e-42 145.4 9.3 2.3 1 1 0 1 1 1 1 POT family Rod_cone_degen PF15201.1 KFX90654.1 - 0.0037 17.0 0.1 0.25 11.2 0.0 2.4 2 0 0 2 2 2 1 Progressive rod-cone degeneration PPI_Ypi1 PF07491.6 KFX90660.1 - 0.0012 18.4 2.2 0.0033 17.0 1.5 1.8 1 1 0 1 1 1 1 Protein phosphatase inhibitor DUF605 PF04652.11 KFX90660.1 - 5.2 6.3 12.4 5.7 6.2 8.6 1.1 1 0 0 1 1 1 0 Vta1 like Ribonuc_L-PSP PF01042.16 KFX90661.1 - 7.5e-39 132.2 0.0 8.4e-39 132.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DDE_Tnp_4 PF13359.1 KFX90661.1 - 0.091 12.3 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease Aldo_ket_red PF00248.16 KFX90664.1 - 5.9e-47 159.8 0.0 9.5e-47 159.1 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_16 PF00722.16 KFX90664.1 - 1.9e-40 138.1 1.6 3.2e-40 137.3 1.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fungal_trans PF04082.13 KFX90664.1 - 9.3e-07 27.9 0.0 2.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_M22 PF00814.20 KFX90671.1 - 2.2e-82 276.6 0.0 2.5e-82 276.3 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Staygreen PF12638.2 KFX90671.1 - 0.14 11.6 0.0 0.73 9.3 0.0 2.0 2 0 0 2 2 2 0 Staygreen protein AMPKBI PF04739.10 KFX90672.1 - 1.7e-29 101.6 0.7 1.7e-29 101.6 0.5 2.3 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain Pribosyl_synth PF14572.1 KFX90672.1 - 0.18 11.5 0.8 0.38 10.4 0.5 1.5 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain MCPVI PF02993.9 KFX90672.1 - 9.2 6.3 14.7 6.6 6.8 0.3 2.6 2 0 0 2 2 2 0 Minor capsid protein VI EpsG PF14897.1 KFX90673.1 - 0.0038 16.1 0.1 0.005 15.8 0.1 1.1 1 0 0 1 1 1 1 EpsG family DUF3034 PF11231.3 KFX90673.1 - 0.027 13.8 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3034) Pkinase PF00069.20 KFX90674.1 - 1.7e-60 204.4 0.0 2.1e-60 204.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX90674.1 - 8e-26 90.6 0.0 1.4e-24 86.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX90674.1 - 0.048 12.6 0.0 0.15 11.0 0.0 1.7 2 1 0 2 2 2 0 Kinase-like Peptidase_C78 PF07910.8 KFX90676.1 - 4e-66 222.2 0.0 8e-66 221.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C78 Ham1p_like PF01725.11 KFX90676.1 - 8.1e-52 175.3 0.0 1.2e-51 174.7 0.0 1.3 1 0 0 1 1 1 1 Ham1 family zf-Di19 PF05605.7 KFX90676.1 - 0.017 15.2 0.2 0.24 11.5 0.0 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding AAA_18 PF13238.1 KFX90677.1 - 1.4e-27 96.5 0.7 2e-27 96.0 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFX90677.1 - 3e-16 60.3 0.5 5.1e-16 59.5 0.3 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KFX90677.1 - 6.7e-06 26.3 0.1 0.00047 20.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KFX90677.1 - 7.8e-05 22.5 0.1 0.00019 21.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain ADK PF00406.17 KFX90677.1 - 0.00012 22.0 0.6 0.0037 17.1 0.4 2.4 1 1 0 1 1 1 1 Adenylate kinase AAA_28 PF13521.1 KFX90677.1 - 0.00016 21.7 0.0 0.00029 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 KFX90677.1 - 0.0003 20.5 0.0 0.00057 19.6 0.0 1.6 1 0 0 1 1 1 1 NTPase Thymidylate_kin PF02223.12 KFX90677.1 - 0.00071 19.0 0.5 0.49 9.7 0.1 2.1 2 0 0 2 2 2 2 Thymidylate kinase KTI12 PF08433.5 KFX90677.1 - 0.00074 18.8 0.1 0.0024 17.1 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 FtsK_SpoIIIE PF01580.13 KFX90677.1 - 0.0017 17.8 0.5 0.0032 16.9 0.1 1.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family SKI PF01202.17 KFX90677.1 - 0.002 18.0 1.2 0.015 15.2 0.8 2.0 1 1 0 1 1 1 1 Shikimate kinase AAA_22 PF13401.1 KFX90677.1 - 0.0025 17.9 0.0 0.0055 16.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KFX90677.1 - 0.0068 16.2 0.1 0.019 14.8 0.0 1.8 1 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KFX90677.1 - 0.0077 16.3 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 KFX90677.1 - 0.0077 16.2 0.0 0.017 15.1 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 KFX90677.1 - 0.017 14.5 0.1 0.032 13.6 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 KFX90677.1 - 0.03 13.9 0.1 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KFX90677.1 - 0.032 13.8 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KFX90677.1 - 0.046 13.4 0.2 0.083 12.6 0.2 1.4 1 0 0 1 1 1 0 Part of AAA domain MobB PF03205.9 KFX90677.1 - 0.048 13.3 0.1 0.087 12.5 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dna2 PF08696.6 KFX90677.1 - 0.06 12.6 0.5 0.13 11.5 0.3 1.5 1 0 0 1 1 1 0 DNA replication factor Dna2 AAA_10 PF12846.2 KFX90677.1 - 0.061 12.7 0.0 0.094 12.1 0.0 1.4 2 0 0 2 2 2 0 AAA-like domain SRP54 PF00448.17 KFX90677.1 - 0.066 12.6 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.9 KFX90677.1 - 0.081 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Cytidylate_kin2 PF13189.1 KFX90677.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 Cytidylate kinase-like family ATP_bind_1 PF03029.12 KFX90677.1 - 0.1 12.1 0.9 0.14 11.6 0.1 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 KFX90677.1 - 0.1 11.3 0.8 0.14 10.9 0.1 1.6 2 0 0 2 2 2 0 ArgK protein Viral_helicase1 PF01443.13 KFX90677.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.7 KFX90677.1 - 0.13 11.2 0.1 0.22 10.5 0.1 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus T2SE PF00437.15 KFX90677.1 - 0.18 10.6 2.1 0.15 10.9 0.4 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Myosin_head PF00063.16 KFX90678.1 - 5e-243 808.1 0.0 5e-243 808.1 0.0 1.5 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 KFX90678.1 - 1.5e-34 118.0 3.6 4.3e-34 116.5 2.5 1.9 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 KFX90678.1 - 4.3e-13 47.6 29.4 0.00015 21.1 0.8 6.8 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_22 PF13401.1 KFX90678.1 - 0.0011 19.1 0.1 0.0055 16.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain Myosin_N PF02736.14 KFX90678.1 - 0.0096 15.5 0.2 0.025 14.2 0.1 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.1 KFX90678.1 - 0.013 15.4 0.2 0.065 13.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 KFX90678.1 - 0.018 14.7 0.0 0.047 13.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain zf-C4H2 PF10146.4 KFX90678.1 - 0.077 13.0 6.5 0.23 11.4 4.5 1.8 1 0 0 1 1 1 0 Zinc finger-containing protein Reo_sigmaC PF04582.7 KFX90678.1 - 0.6 9.2 3.3 1.2 8.1 1.2 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 KFX90678.1 - 2.7 7.9 8.8 0.19 11.6 0.3 3.3 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) ABC_tran PF00005.22 KFX90678.1 - 2.8 8.2 8.2 2.8 8.2 0.0 4.2 4 1 0 4 4 3 0 ABC transporter ArgJ PF01960.13 KFX90679.1 - 3.2e-148 493.2 0.3 3.7e-148 493.0 0.2 1.0 1 0 0 1 1 1 1 ArgJ family A_deamin PF02137.13 KFX90679.1 - 0.16 11.2 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Adenosine-deaminase (editase) domain ORC2 PF04084.9 KFX90680.1 - 2.9e-104 348.4 0.0 3.5e-104 348.1 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 AT_hook PF02178.14 KFX90680.1 - 0.12 12.1 19.2 0.62 9.9 2.6 3.1 2 0 0 2 2 2 0 AT hook motif zf-PARP PF00645.13 KFX90681.1 - 2.5e-05 24.4 0.0 4.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF410 PF04190.8 KFX90682.1 - 2.5e-51 174.7 0.0 3.1e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) fn3 PF00041.16 KFX90700.1 - 5.6e-08 32.8 0.0 1.8e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain LNS2 PF08235.8 KFX90701.1 - 5.3e-70 234.0 0.0 8.7e-70 233.3 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 KFX90701.1 - 1.1e-40 137.6 0.0 2.4e-40 136.6 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 KFX90701.1 - 0.097 12.0 0.0 0.46 9.8 0.0 2.0 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Peptidase_M49 PF03571.10 KFX90702.1 - 2.4e-214 712.4 0.0 3e-214 712.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Glucosamine_iso PF01182.15 KFX90702.1 - 0.007 16.1 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 4HBT_3 PF13622.1 KFX90703.1 - 1.1e-33 117.0 0.0 1.7e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily MFS_1 PF07690.11 KFX90703.1 - 1.6e-31 109.3 29.0 1.6e-31 109.3 20.1 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily 4HBT PF03061.17 KFX90703.1 - 0.0011 19.1 0.0 0.0044 17.1 0.0 2.0 2 0 0 2 2 2 1 Thioesterase superfamily TMEM237 PF15383.1 KFX90703.1 - 0.11 11.6 0.2 0.51 9.4 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 237 Zn_clus PF00172.13 KFX90704.1 - 1.2e-06 28.2 8.4 2.4e-06 27.3 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PEP_mutase PF13714.1 KFX90705.1 - 9.9e-49 165.6 0.4 1.3e-48 165.2 0.3 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase MaoC_dehydratas PF01575.14 KFX90705.1 - 1.3e-21 76.1 0.0 2.5e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain ICL PF00463.16 KFX90705.1 - 6.2e-21 74.2 0.2 9.4e-21 73.6 0.2 1.2 1 0 0 1 1 1 1 Isocitrate lyase family Inhibitor_I9 PF05922.11 KFX90709.1 - 0.045 14.3 0.0 5.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Peptidase inhibitor I9 Aminotran_1_2 PF00155.16 KFX90713.1 - 4.2e-25 88.4 0.0 6.4e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Abhydrolase_6 PF12697.2 KFX90713.1 - 7.8e-16 58.6 0.0 1.5e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX90713.1 - 1.6e-07 31.1 0.0 7.7e-07 28.8 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold OKR_DC_1 PF01276.15 KFX90713.1 - 0.25 9.8 0.0 11 4.4 0.0 2.1 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_3 PF00202.16 KFX90714.1 - 1.3e-39 136.0 0.0 1e-23 83.7 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 KFX90714.1 - 9.4e-34 116.7 0.0 1.5e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 KFX90714.1 - 0.035 13.5 0.1 0.13 11.6 0.1 1.9 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain p450 PF00067.17 KFX90715.1 - 1.9e-59 201.4 0.0 2.5e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 KFX90716.1 - 2.5e-17 63.0 0.0 4.1e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX90716.1 - 2.7e-08 34.1 0.0 5.8e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX90716.1 - 6e-07 29.1 0.0 5.5e-06 26.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX90716.1 - 9e-07 29.4 0.0 1.5e-05 25.5 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX90716.1 - 7.1e-06 26.4 0.0 4e-05 24.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX90716.1 - 0.0012 18.8 0.0 0.0044 17.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX90716.1 - 0.0016 18.7 0.0 0.0031 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KFX90716.1 - 0.0031 17.5 0.0 0.0066 16.4 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 KFX90716.1 - 0.0065 15.5 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 KFX90716.1 - 0.058 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 KFX90716.1 - 0.074 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AA_permease_2 PF13520.1 KFX90736.1 - 6e-36 123.8 33.0 4.3e-35 121.0 24.2 1.4 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.16 KFX90736.1 - 3.5e-12 45.4 26.8 4.4e-12 45.0 18.6 1.1 1 0 0 1 1 1 1 Amino acid permease GRP PF07172.6 KFX90737.1 - 0.0049 17.3 8.3 0.0049 17.3 5.7 3.9 2 1 0 2 2 2 1 Glycine rich protein family EMG1 PF03587.9 KFX90738.1 - 8.6e-78 260.2 0.0 1e-77 260.0 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase GPI-anchored PF10342.4 KFX90747.1 - 3.6e-07 30.5 0.0 4.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Antimicrobial10 PF08105.6 KFX90747.1 - 0.34 10.5 2.4 0.54 9.9 1.7 1.7 1 1 0 1 1 1 0 Metchnikowin family Glyco_hydro_38 PF01074.17 KFX90749.1 - 8.7e-87 290.8 0.6 1.4e-86 290.2 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KFX90749.1 - 5.5e-72 243.0 0.0 9.4e-72 242.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KFX90749.1 - 3.3e-26 91.3 0.0 6.8e-26 90.2 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain DeoC PF01791.4 KFX90751.1 - 3.6e-41 140.9 2.4 4.6e-41 140.6 1.6 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase His_biosynth PF00977.16 KFX90751.1 - 0.015 14.5 0.2 0.022 14.0 0.1 1.4 1 1 0 1 1 1 0 Histidine biosynthesis protein SRF-TF PF00319.13 KFX90753.1 - 3e-23 80.8 0.3 4.2e-23 80.3 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF3246 PF11596.3 KFX90753.1 - 0.015 14.5 0.1 0.02 14.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) CDC45 PF02724.9 KFX90753.1 - 0.18 9.8 0.1 0.22 9.5 0.0 1.1 1 0 0 1 1 1 0 CDC45-like protein FGGY_C PF02782.11 KFX90757.1 - 7.8e-48 162.7 0.2 1.1e-47 162.1 0.1 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KFX90757.1 - 1.3e-24 86.8 0.3 5.1e-22 78.3 0.0 2.4 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KFX90757.1 - 0.0018 17.6 0.1 0.013 14.7 0.0 2.1 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family Hexokinase_1 PF00349.16 KFX90757.1 - 0.0019 17.5 0.0 0.0097 15.2 0.0 1.9 2 0 0 2 2 2 1 Hexokinase ADH_N PF08240.7 KFX90758.1 - 1.6e-30 105.0 1.7 3.2e-30 104.0 1.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX90758.1 - 1.2e-23 83.1 0.3 1.8e-23 82.4 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX90758.1 - 0.00012 22.9 0.0 0.00026 21.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KFX90758.1 - 0.007 15.7 0.2 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 KFX90758.1 - 0.013 16.0 0.0 0.038 14.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 KFX90758.1 - 0.039 13.0 0.0 0.067 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NADH_4Fe-4S PF10589.4 KFX90758.1 - 0.11 11.6 2.7 0.24 10.6 1.9 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Sugar_tr PF00083.19 KFX90759.1 - 2.5e-48 164.7 5.8 3.1e-48 164.4 4.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX90759.1 - 1.5e-19 69.9 9.2 1.8e-19 69.6 6.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFX90759.1 - 0.00055 18.4 2.0 0.00055 18.4 1.4 1.6 1 1 0 1 1 1 1 MFS/sugar transport protein TRI12 PF06609.8 KFX90759.1 - 0.025 12.8 4.3 0.034 12.3 3.0 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 KFX90759.1 - 0.032 12.3 3.0 0.043 11.8 0.0 2.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Rick_17kDa_Anti PF05433.10 KFX90759.1 - 0.33 10.6 4.0 0.81 9.4 2.8 1.7 1 0 0 1 1 1 0 Glycine zipper 2TM domain WD40 PF00400.27 KFX90761.1 - 2.4e-16 58.8 15.1 1.2e-06 28.0 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat Rax2 PF12768.2 KFX90761.1 - 0.0056 15.9 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Cortical protein marker for cell polarity DUF1664 PF07889.7 KFX90762.1 - 0.00059 19.6 0.1 0.00071 19.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) APG6 PF04111.7 KFX90762.1 - 0.007 15.4 1.5 0.0076 15.3 1.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg6 Exonuc_VII_S PF02609.11 KFX90762.1 - 0.018 14.8 1.0 0.018 14.8 0.7 1.6 2 0 0 2 2 2 0 Exonuclease VII small subunit PilJ PF13675.1 KFX90762.1 - 0.021 15.1 0.9 0.026 14.8 0.6 1.2 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term EcsC PF12787.2 KFX90762.1 - 0.023 14.0 0.9 0.028 13.8 0.6 1.0 1 0 0 1 1 1 0 EcsC protein family DUF812 PF05667.6 KFX90762.1 - 0.041 12.3 1.6 0.047 12.1 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Bac_GDH PF05088.7 KFX90762.1 - 0.052 10.9 0.3 0.054 10.9 0.2 1.0 1 0 0 1 1 1 0 Bacterial NAD-glutamate dehydrogenase FUSC PF04632.7 KFX90762.1 - 0.06 11.7 1.9 0.059 11.8 1.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4404 PF14357.1 KFX90762.1 - 0.089 13.2 3.2 0.12 12.8 1.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) Uds1 PF15456.1 KFX90762.1 - 0.092 12.7 1.5 0.12 12.3 1.0 1.3 1 0 0 1 1 1 0 Up-regulated During Septation Paralemmin PF03285.10 KFX90762.1 - 0.096 12.1 4.9 0.11 11.8 3.4 1.2 1 0 0 1 1 1 0 Paralemmin DUF4140 PF13600.1 KFX90762.1 - 0.67 10.4 6.7 2 8.9 3.6 2.0 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Orbi_VP2 PF00898.12 KFX90768.1 - 0.34 8.3 0.0 0.48 7.9 0.0 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP2 Glyco_hydro_18 PF00704.23 KFX90769.1 - 4.1e-18 65.9 3.6 1.8e-17 63.8 0.3 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.23 KFX90770.1 - 1.7e-97 326.9 7.3 2e-97 326.6 5.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LRR_6 PF13516.1 KFX90773.1 - 0.014 15.4 11.0 20 5.6 0.0 6.7 7 0 0 7 7 7 0 Leucine Rich repeat LRR_4 PF12799.2 KFX90773.1 - 0.014 15.0 6.5 2.5 7.8 0.1 4.9 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFX90773.1 - 0.38 10.9 7.6 65 4.1 0.0 6.5 6 1 1 7 7 7 0 Leucine Rich Repeat FLO_LFY PF01698.11 KFX90773.1 - 9.1 5.0 10.7 16 4.2 7.4 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein MFS_1 PF07690.11 KFX90774.1 - 5e-31 107.6 37.7 5e-31 107.6 26.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 KFX90774.1 - 0.0013 18.2 4.2 0.0029 17.1 2.9 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Pyr_redox_3 PF13738.1 KFX90775.1 - 1e-19 71.3 0.0 4e-19 69.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFX90775.1 - 2e-14 53.2 0.0 5.5e-10 38.6 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KFX90775.1 - 3e-10 38.9 0.0 1.2e-09 36.8 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like SnoaL_2 PF12680.2 KFX90775.1 - 0.00046 20.5 0.1 0.0045 17.3 0.0 2.3 2 0 0 2 2 2 1 SnoaL-like domain SnoaL_4 PF13577.1 KFX90775.1 - 0.0014 18.5 0.3 0.0061 16.4 0.0 2.1 2 0 0 2 2 2 1 SnoaL-like domain Pyr_redox_2 PF07992.9 KFX90775.1 - 0.0022 17.8 0.7 0.55 10.0 0.2 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KFX90775.1 - 0.0028 17.7 0.0 0.0075 16.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KFX90775.1 - 0.015 15.6 2.8 0.054 13.9 0.1 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF4440 PF14534.1 KFX90775.1 - 0.022 14.9 0.0 0.064 13.4 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Thi4 PF01946.12 KFX90775.1 - 0.095 11.7 0.0 1.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Thi4 family AMP-binding PF00501.23 KFX90776.1 - 4.1e-90 302.1 0.0 4.9e-90 301.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX90776.1 - 5e-10 40.1 0.1 1.4e-09 38.7 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SUI1 PF01253.17 KFX90781.1 - 1.1e-22 79.6 0.2 2.4e-22 78.5 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Nbl1_Borealin_N PF10444.4 KFX90782.1 - 2.1e-21 75.0 2.1 2.1e-21 75.0 1.4 1.7 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal VWA_2 PF13519.1 KFX90783.1 - 4.7e-14 52.8 0.1 6.7e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KFX90783.1 - 1.4e-07 31.3 0.3 2e-07 30.8 0.2 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 KFX90783.1 - 4.5e-07 29.6 0.1 6.7e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.15 KFX90783.1 - 0.00061 19.1 1.1 0.0018 17.7 0.8 1.8 1 0 0 1 1 1 1 Ubiquitin interaction motif Sybindin PF04099.7 KFX90784.1 - 3.3e-51 172.7 0.0 4.2e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KFX90784.1 - 1.8e-09 37.5 0.1 3.1e-09 36.7 0.1 1.6 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region DUF4375 PF14300.1 KFX90784.1 - 0.09 12.7 0.1 0.4 10.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Got1 PF04178.7 KFX90788.1 - 1.9e-31 108.6 15.7 2.9e-31 108.0 10.9 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family Peptidase_M50 PF02163.17 KFX90788.1 - 0.048 12.6 0.0 0.058 12.3 0.0 1.3 1 1 0 1 1 1 0 Peptidase family M50 NuA4 PF09340.5 KFX90791.1 - 8.5e-24 83.0 0.1 1.3e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 RNase_PH PF01138.16 KFX90795.1 - 1.8e-33 115.6 0.0 3.5e-33 114.7 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Thioredoxin PF00085.15 KFX90796.1 - 1.4e-32 111.4 0.1 1.3e-26 92.2 0.1 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 KFX90796.1 - 1e-09 38.5 1.6 1.8e-06 27.8 0.0 2.5 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KFX90796.1 - 4.5e-07 30.0 3.9 2.3e-05 24.5 0.2 3.3 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFX90796.1 - 3.1e-06 27.1 0.1 0.00062 19.8 0.0 3.4 3 1 0 3 3 3 1 Thioredoxin-like Thioredoxin_3 PF13192.1 KFX90796.1 - 0.014 15.2 0.1 0.76 9.6 0.0 2.9 2 0 0 2 2 2 0 Thioredoxin domain AhpC-TSA PF00578.16 KFX90796.1 - 0.018 14.7 0.0 0.051 13.2 0.0 1.7 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_7 PF13899.1 KFX90796.1 - 0.018 15.0 0.0 0.06 13.3 0.0 2.0 1 0 0 1 1 1 0 Thioredoxin-like X PF00739.14 KFX90796.1 - 0.11 12.3 0.1 0.44 10.4 0.0 2.0 2 0 0 2 2 2 0 Trans-activation protein X NARP1 PF12569.3 KFX90796.1 - 3 6.4 11.5 4.5 5.9 8.0 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ank_2 PF12796.2 KFX90798.1 - 7.8e-05 22.9 0.0 0.0017 18.6 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFX90798.1 - 0.00065 19.3 0.0 9.4 6.2 0.0 4.2 3 1 1 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 KFX90798.1 - 0.00089 19.2 0.0 41 4.8 0.0 4.6 3 1 1 4 4 4 0 Ankyrin repeat Ank_4 PF13637.1 KFX90798.1 - 0.035 14.6 0.0 1.7 9.2 0.0 3.2 4 0 0 4 4 4 0 Ankyrin repeats (many copies) BEX PF04538.7 KFX90802.1 - 0.038 14.1 0.0 0.072 13.3 0.0 1.4 1 0 0 1 1 1 0 Brain expressed X-linked like family TIM PF00121.13 KFX90803.1 - 2.7e-89 298.4 0.5 3e-89 298.2 0.4 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase FtsZ_C PF12327.3 KFX90803.1 - 0.041 13.9 0.8 16 5.6 0.0 3.1 2 1 1 3 3 3 0 FtsZ family, C-terminal domain L51_S25_CI-B8 PF05047.11 KFX90804.1 - 9.6e-15 54.0 0.0 1.4e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.3 KFX90805.1 - 5.1e-31 106.8 2.1 5.1e-31 106.8 1.4 1.7 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 KFX90805.1 - 3.8e-17 61.6 0.3 1.8e-16 59.5 0.2 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX90805.1 - 6.2e-12 45.3 0.0 1.3e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX90805.1 - 1.2e-07 31.4 0.2 4.2e-07 29.6 0.1 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) STAG PF08514.6 KFX90806.1 - 8.8e-25 86.7 0.2 2.6e-24 85.1 0.1 1.8 1 0 0 1 1 1 1 STAG domain HEAT_2 PF13646.1 KFX90806.1 - 2.6e-06 27.6 0.0 0.00018 21.6 0.0 3.2 2 1 1 3 3 3 2 HEAT repeats Histidinol_dh PF00815.15 KFX90806.1 - 8.2e-05 21.4 0.2 0.00014 20.5 0.1 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase HEAT PF02985.17 KFX90806.1 - 0.0099 15.8 0.1 20 5.5 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat HATPase_c_3 PF13589.1 KFX90808.1 - 3.6e-16 59.0 0.0 7.1e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KFX90808.1 - 0.00011 21.8 0.1 0.00044 19.9 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 KFX90808.1 - 0.014 15.0 0.0 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 MutL C terminal dimerisation domain CFEM PF05730.6 KFX90809.1 - 0.13 12.1 10.5 0.21 11.4 7.2 1.3 1 0 0 1 1 1 0 CFEM domain Dabb PF07876.7 KFX90810.1 - 1.1e-21 77.0 0.1 1.3e-21 76.8 0.1 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain GHMP_kinases_N PF00288.21 KFX90811.1 - 2.5e-12 46.6 0.1 5.8e-12 45.4 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KFX90811.1 - 7.7e-05 22.8 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal NPP1 PF05630.6 KFX90819.1 - 3.3e-07 30.2 2.1 3.3e-07 30.2 1.5 2.4 2 1 1 3 3 3 1 Necrosis inducing protein (NPP1) Glyco_hydro_28 PF00295.12 KFX90820.1 - 6.1e-49 166.7 0.8 8.4e-49 166.2 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 ET PF01684.11 KFX90820.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 ET module ORC6 PF05460.8 KFX90822.1 - 6.9e-47 160.2 0.5 3.1e-46 158.1 0.4 1.8 1 1 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) EF-hand_6 PF13405.1 KFX90823.1 - 5e-07 29.0 2.2 0.035 13.9 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 KFX90823.1 - 1.5e-05 23.9 0.5 0.0001 21.3 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 KFX90823.1 - 2.4e-05 23.4 0.6 0.00013 21.1 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 KFX90823.1 - 2.7e-05 24.2 4.5 0.0046 17.0 0.9 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KFX90823.1 - 4.7e-05 22.9 1.1 0.00012 21.6 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain pair cobW PF02492.14 KFX90825.1 - 3.1e-21 75.5 0.0 4.4e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KFX90825.1 - 0.0059 15.4 0.0 0.0067 15.2 0.0 1.1 1 0 0 1 1 1 1 ArgK protein Ycf1 PF05758.7 KFX90826.1 - 0.046 11.4 1.2 0.061 11.0 0.8 1.2 1 0 0 1 1 1 0 Ycf1 Peptidase_S49_N PF08496.5 KFX90826.1 - 0.61 9.8 13.2 1.3 8.8 9.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SKN1 PF03935.10 KFX90827.1 - 3.3e-225 747.9 0.4 3.8e-225 747.7 0.3 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) CHD5 PF04420.9 KFX90829.1 - 1.6e-54 183.9 0.6 2e-54 183.5 0.4 1.1 1 0 0 1 1 1 1 CHD5-like protein GCN5L1 PF06320.8 KFX90829.1 - 0.042 13.6 0.7 0.068 12.9 0.5 1.3 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) PPTA PF01239.17 KFX90830.1 - 9e-08 31.1 19.8 0.0011 18.2 0.7 5.1 5 0 0 5 5 5 3 Protein prenyltransferase alpha subunit repeat Dimer_Tnp_hAT PF05699.9 KFX90830.1 - 0.065 12.8 0.2 0.26 10.9 0.0 2.1 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region Asp PF00026.18 KFX90832.1 - 1.3e-67 228.3 4.2 1.6e-67 228.0 2.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFX90832.1 - 1.2e-07 31.8 0.6 3.1e-07 30.5 0.0 2.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KFX90832.1 - 6.9e-06 26.4 0.1 0.082 13.4 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KFX90832.1 - 0.0029 17.1 0.0 0.11 12.0 0.0 2.3 1 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 KFX90832.1 - 0.0084 15.9 0.0 6.3 6.7 0.0 2.5 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP PF00077.15 KFX90832.1 - 0.029 14.2 0.0 0.71 9.8 0.0 2.4 2 0 0 2 2 2 0 Retroviral aspartyl protease DNA_methylase PF00145.12 KFX90833.1 - 0.08 12.0 2.2 0.094 11.8 1.5 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Med19 PF10278.4 KFX90848.1 - 0.018 14.7 9.5 0.02 14.5 6.6 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 MDFI PF15316.1 KFX90848.1 - 0.12 12.3 2.4 0.13 12.2 1.7 1.2 1 0 0 1 1 1 0 MyoD family inhibitor VAD1-2 PF15310.1 KFX90848.1 - 0.18 11.4 6.5 0.24 11.0 4.5 1.1 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling YqfQ PF14181.1 KFX90848.1 - 0.49 10.4 7.3 0.61 10.1 5.0 1.1 1 0 0 1 1 1 0 YqfQ-like protein RNA_polI_A34 PF08208.6 KFX90848.1 - 1.7 8.2 12.6 2 8.0 8.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Herpes_DNAp_acc PF04929.7 KFX90848.1 - 3.6 6.4 8.8 4 6.3 6.1 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TSGP1 PF07771.6 KFX90848.1 - 6.8 6.6 9.1 11 5.9 6.3 1.3 1 0 0 1 1 1 0 Tick salivary peptide group 1 RNase_H2-Ydr279 PF09468.5 KFX90848.1 - 8.8 5.4 8.6 9.5 5.3 6.0 1.0 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) JmjC PF02373.17 KFX90849.1 - 1.4e-39 134.8 0.3 3.6e-39 133.5 0.2 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 KFX90849.1 - 4e-19 68.6 3.5 7.5e-19 67.7 2.4 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KFX90849.1 - 4.5e-16 58.7 2.2 9.6e-16 57.7 1.5 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain WD40 PF00400.27 KFX90864.1 - 1.2e-23 82.1 5.3 7.1e-08 32.0 0.0 7.5 8 0 0 8 8 8 5 WD domain, G-beta repeat DUF3639 PF12341.3 KFX90864.1 - 1.3e-09 37.8 2.0 1.3e-09 37.8 1.4 3.4 5 0 0 5 5 5 1 Protein of unknown function (DUF3639) Coatomer_WDAD PF04053.9 KFX90864.1 - 1.6e-06 27.1 0.0 3.6e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region eIF2A PF08662.6 KFX90864.1 - 4.4e-05 23.2 0.1 0.0054 16.4 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KFX90864.1 - 0.03 12.1 0.1 0.094 10.5 0.0 1.7 1 1 1 2 2 2 0 IKI3 family DNA_pol_alpha_N PF12254.3 KFX90864.1 - 0.056 13.2 3.1 0.16 11.8 2.2 1.7 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Apc4_WD40 PF12894.2 KFX90864.1 - 0.067 12.7 0.0 52 3.4 0.0 3.3 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 KFX90865.1 - 4.1e-22 77.1 13.8 7.3e-05 22.4 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 KFX90865.1 - 0.041 12.0 1.2 5.3 5.0 0.0 2.9 2 1 0 2 2 2 0 Nucleoporin Nup120/160 PQQ_3 PF13570.1 KFX90865.1 - 0.099 12.9 0.6 2.9 8.2 0.0 3.6 4 0 0 4 4 4 0 PQQ-like domain Sigma70_ner PF04546.8 KFX90866.1 - 0.21 11.2 2.7 0.48 10.0 1.9 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.1 KFX90866.1 - 0.9 9.2 4.0 2.3 7.9 2.8 1.6 1 0 0 1 1 1 0 FAM176 family Ku_N PF03731.10 KFX90867.1 - 1.9e-34 119.0 0.0 2.5e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 KFX90867.1 - 1.6e-33 115.8 0.0 3.3e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain VWA_2 PF13519.1 KFX90867.1 - 0.0083 16.2 0.1 0.023 14.8 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain Complex1_51K PF01512.12 KFX90867.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit CAF1A PF12253.3 KFX90867.1 - 4.3 7.5 9.4 9.1 6.4 6.5 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A Ferrochelatase PF00762.14 KFX90868.1 - 9e-91 304.1 0.0 1e-90 303.9 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase MFS_1 PF07690.11 KFX90869.1 - 2.2e-22 79.2 39.5 1.4e-16 60.1 16.8 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Amidohydro_1 PF01979.15 KFX90870.1 - 2e-39 136.2 0.0 2.7e-39 135.7 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KFX90870.1 - 7.7e-06 25.3 0.1 2.2e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Amidohydrolase family cNMP_binding PF00027.24 KFX90871.1 - 6.3e-40 134.9 0.1 6.1e-20 70.8 0.0 4.7 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 KFX90871.1 - 7.1e-18 65.2 7.5 4.2e-17 62.7 3.6 3.2 2 1 0 2 2 2 1 Patatin-like phospholipase DUF3568 PF12092.3 KFX90871.1 - 0.17 11.6 0.0 0.43 10.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) EIF_2_alpha PF07541.7 KFX90872.1 - 2.8e-38 130.1 0.0 5.6e-38 129.1 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KFX90872.1 - 1.5e-12 47.3 1.0 3.3e-12 46.3 0.7 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Peptidase_S24 PF00717.18 KFX90872.1 - 0.00036 20.1 0.8 0.0028 17.2 0.0 2.9 2 2 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.4 KFX90872.1 - 0.0015 18.0 0.1 0.012 15.0 0.0 2.3 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Bacteriocin_IIi PF11758.3 KFX90872.1 - 0.14 11.7 0.1 0.14 11.7 0.1 2.2 2 0 0 2 2 2 0 Aureocin-like type II bacteriocin Mito_carr PF00153.22 KFX90873.1 - 1.9e-64 213.3 4.2 6.8e-22 76.9 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein Ribonuc_L-PSP PF01042.16 KFX90874.1 - 1.8e-25 89.0 0.0 2.1e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF1320 PF07030.7 KFX90874.1 - 0.02 14.6 0.1 0.047 13.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1320) KAR9 PF08580.5 KFX90897.1 - 3.4e-118 395.7 0.0 4.5e-118 395.4 0.0 1.1 1 0 0 1 1 1 1 Yeast cortical protein KAR9 Syntaxin-6_N PF09177.6 KFX90897.1 - 0.02 15.2 6.3 0.41 11.0 0.6 4.1 3 2 1 4 4 4 0 Syntaxin 6, N-terminal FlaC_arch PF05377.6 KFX90897.1 - 0.16 11.9 1.1 24 4.9 0.1 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Spectrin PF00435.16 KFX90897.1 - 1.5 9.1 12.8 7.4 6.9 0.0 4.7 4 1 0 4 4 4 0 Spectrin repeat Amidase PF01425.16 KFX90901.1 - 1.8e-78 264.3 0.2 5.2e-76 256.2 0.0 2.0 2 0 0 2 2 2 2 Amidase Sigma70_r1_1 PF03979.9 KFX90901.1 - 0.038 13.9 0.1 9.3 6.2 0.1 2.4 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 Histone PF00125.19 KFX90902.1 - 4.5e-22 77.9 0.0 5.8e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFX90902.1 - 4.9e-05 23.2 0.0 7.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-H2C2_2 PF13465.1 KFX90913.1 - 1.6e-13 50.2 10.0 9.6e-08 31.9 0.3 3.9 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFX90913.1 - 2.6e-11 43.1 12.6 8.5e-06 25.8 1.6 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX90913.1 - 1.5e-10 40.6 12.8 4.1e-05 23.6 1.8 3.9 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFX90913.1 - 7.8e-07 29.0 4.7 0.031 14.4 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFX90913.1 - 5.3e-05 23.2 2.3 0.015 15.5 0.2 3.4 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 KFX90913.1 - 0.045 13.8 2.2 0.093 12.8 1.5 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding LIM PF00412.17 KFX90913.1 - 5.6 7.1 7.7 15 5.7 2.6 2.9 2 1 1 3 3 3 0 LIM domain Pkinase PF00069.20 KFX90916.1 - 4e-49 167.1 0.0 9.5e-29 100.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFX90916.1 - 8.8e-22 77.4 0.0 8e-15 54.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KFX90916.1 - 0.0028 17.4 0.4 0.01 15.6 0.3 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Tricorn_PDZ PF14685.1 KFX90916.1 - 0.12 12.1 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain Pox_ser-thr_kin PF05445.6 KFX90916.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PS_Dcarbxylase PF02666.10 KFX90917.1 - 2.5e-19 69.3 0.0 3.4e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF2407 PF10302.4 KFX90918.1 - 9.6e-07 28.9 0.3 2.5e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 KFX90918.1 - 3e-06 26.5 0.2 6.3e-06 25.4 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KFX90918.1 - 0.0071 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 KFX90918.1 - 0.052 13.4 0.0 0.19 11.5 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DUF1996 PF09362.5 KFX90936.1 - 4.3e-80 268.7 0.2 5.5e-80 268.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) P16-Arc PF04699.9 KFX90938.1 - 1.2e-36 126.0 0.0 1.9e-36 125.3 0.0 1.3 1 1 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Polysacc_lyase PF14099.1 KFX90945.1 - 6.2e-14 52.1 1.8 7.8e-14 51.8 1.3 1.2 1 0 0 1 1 1 1 Polysaccharide lyase PP2C PF00481.16 KFX90946.1 - 1.3e-52 178.7 0.0 2.3e-52 177.9 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 KFX90946.1 - 5e-40 134.5 44.6 3.6e-07 29.6 0.5 12.5 7 3 7 14 14 14 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFX90946.1 - 3.6e-39 132.3 44.7 1.7e-10 40.4 0.6 9.6 5 4 4 10 10 10 9 Leucine rich repeat Guanylate_cyc PF00211.15 KFX90946.1 - 3.1e-28 98.3 0.0 7.4e-28 97.1 0.0 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 KFX90946.1 - 1.4e-22 76.1 46.5 0.13 12.3 0.0 18.9 20 0 0 20 20 20 8 Leucine Rich Repeat LRR_7 PF13504.1 KFX90946.1 - 8e-13 46.3 48.9 0.48 10.8 0.1 16.0 18 0 0 18 18 18 4 Leucine rich repeat RA PF00788.18 KFX90946.1 - 8.9e-13 48.5 0.0 2.1e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Ad_cyc_g-alpha PF08509.6 KFX90946.1 - 2.6e-06 26.6 0.0 1.1e-05 24.6 0.0 2.1 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_9 PF14580.1 KFX90946.1 - 0.0018 17.8 9.7 0.064 12.8 0.1 4.2 2 1 1 4 4 4 2 Leucine-rich repeat LRR_6 PF13516.1 KFX90946.1 - 1.3 9.3 47.4 4.8 7.5 0.2 14.1 18 1 1 19 19 19 0 Leucine Rich repeat DAHP_synth_2 PF01474.11 KFX90954.1 - 1e-190 633.7 0.0 1.2e-190 633.5 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Condensation PF00668.15 KFX90956.1 - 5.3e-54 183.1 0.0 1.2e-33 116.2 0.0 2.5 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KFX90956.1 - 1.4e-08 34.8 0.0 3.3e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Tctex-1 PF03645.8 KFX90957.1 - 2.4e-06 27.2 0.1 2.8e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family UQ_con PF00179.21 KFX90961.1 - 1.2e-24 86.3 0.0 1.6e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFX90961.1 - 0.0061 16.3 0.0 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFX90961.1 - 0.007 16.2 0.1 0.013 15.4 0.1 1.5 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 KFX90961.1 - 0.018 14.7 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 UEV domain UFC1 PF08694.6 KFX90961.1 - 0.052 13.0 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 DUF4246 PF14033.1 KFX90980.1 - 1.1e-89 301.4 0.1 1.3e-89 301.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 KFX90980.1 - 0.011 16.0 0.0 0.028 14.7 0.0 1.7 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.1 KFX90980.1 - 0.078 13.4 0.0 0.22 12.0 0.0 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Aminotran_3 PF00202.16 KFX90981.1 - 4.5e-51 173.6 0.0 5.2e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III HA2 PF04408.18 KFX90982.1 - 2.7e-18 65.8 0.0 8.9e-18 64.2 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFX90982.1 - 1.2e-14 53.9 0.0 7.2e-13 48.2 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KFX90982.1 - 1.7e-10 40.6 0.0 3.7e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KFX90982.1 - 1.4e-07 31.2 0.0 3e-06 26.8 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Daxx PF03344.10 KFX90982.1 - 0.0025 16.4 18.4 0.0025 16.4 12.7 2.9 3 0 0 3 3 3 1 Daxx Family AAA_22 PF13401.1 KFX90982.1 - 0.0035 17.4 0.0 0.017 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KFX90982.1 - 0.0061 15.5 0.2 0.018 13.9 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 KFX90982.1 - 0.037 13.4 0.3 0.09 12.2 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family ResIII PF04851.10 KFX90982.1 - 0.046 13.5 1.3 8 6.2 0.0 3.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit KaiC PF06745.8 KFX90982.1 - 0.056 12.5 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 KaiC Glypican PF01153.14 KFX90982.1 - 1.7 7.1 7.5 3 6.3 5.2 1.3 1 0 0 1 1 1 0 Glypican Preseq_ALAS PF09029.5 KFX90983.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 5-aminolevulinate synthase presequence Shikimate_DH PF01488.15 KFX90983.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DIOX_N PF14226.1 KFX90984.1 - 3.2e-21 76.0 0.0 6.4e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KFX90984.1 - 7.6e-19 67.8 0.0 1.4e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Transcrip_reg PF01709.15 KFX90985.1 - 3.3e-54 183.4 0.0 3.8e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator tRNA-synt_1b PF00579.20 KFX90986.1 - 1.6e-54 185.0 0.0 2.2e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) HSP20 PF00011.16 KFX90987.1 - 1e-09 38.1 0.1 1.4e-09 37.7 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Vac7 PF12751.2 KFX90987.1 - 0.016 14.1 0.2 0.02 13.7 0.1 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Ribosomal_60s PF00428.14 KFX90987.1 - 0.23 11.9 2.8 0.5 10.7 2.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein MSC PF09402.5 KFX90988.1 - 2.9e-86 289.2 0.0 3.4e-86 289.0 0.0 1.0 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain DUF3350 PF11830.3 KFX90988.1 - 0.079 12.9 1.7 3.9 7.5 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3350) Rif1_N PF12231.3 KFX90999.1 - 9.3e-116 386.8 0.0 1.3e-115 386.3 0.0 1.2 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal zf-CCHC_4 PF14392.1 KFX91021.1 - 0.0049 16.5 1.1 0.011 15.3 0.8 1.6 1 0 0 1 1 1 1 Zinc knuckle Selenoprotein_S PF06936.6 KFX91021.1 - 0.039 13.5 1.3 0.042 13.3 0.9 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) VWD PF00094.20 KFX91021.1 - 0.09 12.9 0.1 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type D domain DUF3886 PF13025.1 KFX91021.1 - 0.1 12.5 2.6 0.21 11.5 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Calc_CGRP_IAPP PF00214.14 KFX91021.1 - 0.13 12.3 1.5 0.16 12.0 1.0 1.0 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family zf-CCHC PF00098.18 KFX91021.1 - 0.26 11.2 2.2 0.43 10.5 1.5 1.4 1 0 0 1 1 1 0 Zinc knuckle FRG2 PF15315.1 KFX91021.1 - 0.26 11.2 4.7 0.3 11.0 3.3 1.0 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 GRAB PF10375.4 KFX91024.1 - 6e-07 28.8 0.1 1.2e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Transposase_22 PF02994.9 KFX91024.1 - 0.00039 19.0 14.8 0.00039 19.0 10.3 3.1 1 1 2 3 3 3 1 L1 transposable element Reo_sigmaC PF04582.7 KFX91024.1 - 0.0007 18.8 14.8 0.0082 15.3 4.7 2.9 2 1 1 3 3 3 3 Reovirus sigma C capsid protein DUF3584 PF12128.3 KFX91024.1 - 0.084 10.1 44.7 0.13 9.5 31.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CENP-F_leu_zip PF10473.4 KFX91024.1 - 0.4 10.5 56.4 0.024 14.5 11.4 3.4 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HOOK PF05622.7 KFX91024.1 - 0.59 7.8 47.2 0.91 7.2 2.4 2.1 1 1 1 2 2 2 0 HOOK protein IncA PF04156.9 KFX91024.1 - 1.5 8.3 60.4 2.3 7.7 14.4 4.0 1 1 3 4 4 4 0 IncA protein Rootletin PF15035.1 KFX91024.1 - 1.8 8.4 49.3 0.1 12.5 5.8 3.6 1 1 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion NPV_P10 PF05531.7 KFX91024.1 - 4.7 7.5 21.9 8.4 6.7 0.2 4.9 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Neugrin PF06413.6 KFX91025.1 - 1.4e-10 41.3 0.8 1.4e-10 41.3 0.6 2.1 2 1 0 2 2 2 1 Neugrin MRP-L20 PF12824.2 KFX91025.1 - 0.0013 18.7 7.4 0.0013 18.7 5.1 2.5 2 1 0 3 3 3 1 Mitochondrial ribosomal protein subunit L20 Aminotran_1_2 PF00155.16 KFX91026.1 - 5.7e-65 219.6 0.0 6.8e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KFX91026.1 - 6.7e-05 22.0 0.0 0.00013 21.1 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KFX91026.1 - 0.0063 15.6 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 KFX91026.1 - 0.014 13.7 0.0 0.028 12.7 0.0 1.5 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Methyltransf_11 PF08241.7 KFX91031.1 - 3.6e-16 59.4 0.0 5.5e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX91031.1 - 8.4e-11 42.2 0.0 1.3e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX91031.1 - 7.8e-10 39.3 0.0 1.3e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX91031.1 - 2.5e-09 36.8 0.0 3.4e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX91031.1 - 3.3e-08 33.4 0.0 5.1e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX91031.1 - 5.1e-07 29.9 0.0 8.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 KFX91031.1 - 0.00014 20.8 0.0 0.00022 20.2 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_26 PF13659.1 KFX91031.1 - 0.00052 20.0 0.0 0.0013 18.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX91031.1 - 0.0014 17.7 0.0 0.0022 17.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 KFX91031.1 - 0.003 16.6 0.0 0.0041 16.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase tRNA_U5-meth_tr PF05958.6 KFX91031.1 - 0.028 13.1 0.0 0.04 12.5 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase MTS PF05175.9 KFX91031.1 - 0.091 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain NodS PF05401.6 KFX91031.1 - 0.13 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Glyco_hydro_26 PF02156.10 KFX91032.1 - 3.3e-83 279.7 1.0 4.3e-83 279.3 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 VirC2 PF07181.6 KFX91032.1 - 0.0054 16.1 0.0 0.0088 15.4 0.0 1.2 1 0 0 1 1 1 1 VirC2 protein Yip1 PF04893.12 KFX91033.1 - 5.1e-13 48.8 14.2 5.1e-13 48.8 9.8 1.7 1 1 1 2 2 2 1 Yip1 domain His_Phos_1 PF00300.17 KFX91036.1 - 1.8e-25 89.9 0.0 2.1e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Porin_3 PF01459.17 KFX91037.1 - 2.3e-64 217.3 5.8 2.6e-64 217.1 4.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin OPT PF03169.10 KFX91046.1 - 8.3e-181 602.5 56.9 9.6e-181 602.3 39.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2953 PF11167.3 KFX91046.1 - 0.023 14.5 1.3 0.087 12.7 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2953) DUF2937 PF11157.3 KFX91046.1 - 0.12 11.6 2.6 1.2 8.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) DUF4191 PF13829.1 KFX91046.1 - 4.2 6.4 4.6 8.2 5.4 2.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4191) DASH_Spc34 PF08657.5 KFX91047.1 - 3.7e-31 108.7 4.0 4.3e-31 108.5 2.7 1.0 1 0 0 1 1 1 1 DASH complex subunit Spc34 SlyX PF04102.7 KFX91047.1 - 0.042 14.2 8.1 0.2 12.0 1.0 2.3 1 1 1 2 2 2 0 SlyX DASH_Spc19 PF08287.6 KFX91047.1 - 0.073 12.6 6.5 0.09 12.3 4.2 1.4 1 1 0 1 1 1 0 Spc19 TPR_MLP1_2 PF07926.7 KFX91047.1 - 0.12 12.1 4.1 0.43 10.3 2.5 2.0 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Coa1 PF08695.5 KFX91047.1 - 0.15 11.5 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 KBP_C PF12309.3 KFX91047.1 - 0.29 10.0 3.2 0.35 9.7 2.2 1.1 1 0 0 1 1 1 0 KIF-1 binding protein C terminal MutS_IV PF05190.13 KFX91047.1 - 2.1 8.5 6.3 5.1 7.3 0.2 2.3 2 0 0 2 2 2 0 MutS family domain IV Uds1 PF15456.1 KFX91047.1 - 2.3 8.1 8.1 5.7 6.9 5.6 1.6 1 1 0 1 1 1 0 Up-regulated During Septation IncA PF04156.9 KFX91047.1 - 6.9 6.2 14.1 43 3.6 9.7 2.0 1 1 0 1 1 1 0 IncA protein PspB PF06667.7 KFX91047.1 - 8.9 6.3 6.5 2.3 8.1 1.5 2.1 2 0 0 2 2 2 0 Phage shock protein B ACC_epsilon PF13822.1 KFX91059.1 - 2.8 8.3 5.9 21 5.5 0.1 3.1 2 1 0 2 2 2 0 Acyl-CoA carboxylase epsilon subunit HET PF06985.6 KFX91060.1 - 6.4e-25 87.9 1.5 2.3e-24 86.1 1.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.14 KFX91068.1 - 2.6e-54 184.6 0.0 3.4e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KFX91068.1 - 4.8e-06 25.3 0.2 0.0084 14.6 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.19 KFX91068.1 - 0.00011 21.2 0.1 0.0045 15.9 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFX91068.1 - 0.0011 19.3 0.7 1.2 9.5 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFX91068.1 - 0.0054 15.8 0.0 0.0087 15.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KFX91068.1 - 0.034 12.9 0.1 0.99 8.1 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 KFX91068.1 - 0.069 12.0 0.3 0.43 9.4 0.1 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein NOB1_Zn_bind PF08772.6 KFX91078.1 - 7.3e-33 112.2 2.9 1.2e-32 111.5 2.0 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like AF1Q PF15017.1 KFX91078.1 - 1.4e-07 31.3 8.1 3.7e-07 29.9 5.2 2.2 1 1 0 1 1 1 1 Drug resistance and apoptosis regulator zf-NADH-PPase PF09297.6 KFX91078.1 - 0.0027 17.2 2.3 0.014 14.9 0.1 2.5 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain Gly_transf_sug PF04488.10 KFX91079.1 - 3.8e-12 46.4 0.1 7e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DUF3635 PF12330.3 KFX91081.1 - 0.00011 22.1 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) PQ-loop PF04193.9 KFX91093.1 - 1.2e-20 72.7 8.4 4.6e-15 54.8 0.9 3.1 3 0 0 3 3 3 2 PQ loop repeat GtrA PF04138.9 KFX91093.1 - 0.00067 19.5 0.2 0.0028 17.6 0.1 2.0 1 1 0 1 1 1 1 GtrA-like protein DUF3754 PF12576.3 KFX91093.1 - 0.1 12.2 0.3 0.22 11.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) DUF876 PF05936.7 KFX91093.1 - 0.14 10.5 0.0 0.2 10.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF876) Dynamin_N PF00350.18 KFX91094.1 - 1.5e-42 145.2 0.0 3.1e-42 144.2 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KFX91094.1 - 3e-12 45.9 0.1 4.2e-10 38.8 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 KFX91094.1 - 0.0022 17.9 0.0 0.0092 15.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFX91094.1 - 0.0037 17.7 0.0 0.01 16.3 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 KFX91094.1 - 0.026 14.4 1.7 0.39 10.6 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_21 PF13304.1 KFX91094.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain PALP PF00291.20 KFX91098.1 - 1.2e-42 146.2 0.0 1.3e-42 146.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Chitin_bind_3 PF03067.10 KFX91099.1 - 3.4e-11 43.7 0.0 4.7e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Chitin binding domain 2-Hacid_dh_C PF02826.14 KFX91106.1 - 2.3e-54 183.2 0.0 3.2e-54 182.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFX91106.1 - 1.4e-17 63.4 0.0 1.6e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFX91106.1 - 0.00025 20.9 0.3 0.00044 20.1 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase SUZ PF12752.2 KFX91108.1 - 2.4e-05 24.7 4.0 2.4e-05 24.7 2.8 3.3 2 2 0 2 2 2 1 SUZ domain API5 PF05918.6 KFX91108.1 - 0.096 11.1 3.3 0.11 10.9 2.3 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF2744 PF10910.3 KFX91108.1 - 1.3 8.8 4.1 13 5.6 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2744) Fe_hyd_lg_C PF02906.9 KFX91109.1 - 8.1e-67 225.4 0.0 1.4e-66 224.7 0.0 1.4 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DUF4131 PF13567.1 KFX91110.1 - 0.061 12.7 2.3 0.058 12.7 0.6 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF202 PF02656.10 KFX91110.1 - 8.7 6.6 7.0 14 6.0 0.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF202) EMP24_GP25L PF01105.19 KFX91111.1 - 5.4e-35 120.7 0.0 6.1e-35 120.5 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF1627 PF07789.7 KFX91111.1 - 0.047 13.2 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1627) Arf PF00025.16 KFX91112.1 - 3e-76 254.5 0.1 4e-76 254.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFX91112.1 - 1.4e-13 50.5 0.0 2.4e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KFX91112.1 - 1.2e-12 47.5 0.0 1.5e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KFX91112.1 - 2.1e-11 43.1 1.0 2.5e-09 36.3 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KFX91112.1 - 1.3e-10 40.8 0.0 2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KFX91112.1 - 5.3e-08 33.3 0.0 8.6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFX91112.1 - 8.9e-06 25.6 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Nucleoporin_N PF08801.6 KFX91112.1 - 0.014 14.2 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Nup133 N terminal like 6PF2K PF01591.13 KFX91112.1 - 0.028 13.5 0.1 0.06 12.4 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase AAA_33 PF13671.1 KFX91112.1 - 0.14 12.0 0.1 0.36 10.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain Med3 PF11593.3 KFX91113.1 - 0.84 8.8 22.5 1.4 8.0 15.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal GST_C_2 PF13410.1 KFX91114.1 - 3.6e-08 33.1 1.0 6.4e-08 32.3 0.3 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFX91114.1 - 0.0008 19.3 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain LCD1 PF09798.4 KFX91117.1 - 0.2 9.5 1.7 0.24 9.3 1.2 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein DUF4603 PF15376.1 KFX91117.1 - 0.99 6.5 13.9 1.2 6.2 9.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) FlxA PF14282.1 KFX91117.1 - 5.2 7.0 10.0 9.4 6.2 7.0 1.3 1 0 0 1 1 1 0 FlxA-like protein DnaJ PF00226.26 KFX91120.1 - 6.6e-11 41.7 2.2 1.3e-10 40.7 1.6 1.6 1 1 0 1 1 1 1 DnaJ domain Pkinase PF00069.20 KFX91123.1 - 1.9e-21 76.3 0.0 2.2e-20 72.9 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX91123.1 - 1.2e-08 34.3 0.0 0.0028 16.7 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase COG4 PF08318.7 KFX91124.1 - 9.5e-96 320.4 0.0 1.2e-95 320.0 0.0 1.1 1 0 0 1 1 1 1 COG4 transport protein DZR PF12773.2 KFX91127.1 - 0.99 9.2 6.1 1.4 8.7 0.8 2.2 1 1 1 2 2 2 0 Double zinc ribbon YdjO PF14169.1 KFX91127.1 - 1 8.8 13.7 0.13 11.7 0.9 3.6 1 1 2 3 3 3 0 Cold-inducible protein YdjO TF_Zn_Ribbon PF08271.7 KFX91127.1 - 5.4 6.4 9.2 4.7 6.6 0.1 3.1 2 1 0 2 2 2 0 TFIIB zinc-binding Myosin_head PF00063.16 KFX91128.1 - 7.4e-230 764.6 3.9 1.3e-229 763.7 2.7 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KFX91128.1 - 6.7e-43 146.3 0.0 1.3e-42 145.3 0.0 1.5 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 KFX91128.1 - 2e-15 55.9 0.3 4e-15 54.9 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFX91128.1 - 2.9e-12 45.9 0.1 6.9e-12 44.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFX91128.1 - 8.9e-12 44.3 0.0 1.9e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.22 KFX91128.1 - 0.00053 19.3 5.4 0.2 11.4 0.7 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 KFX91128.1 - 0.0064 16.6 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFX91128.1 - 0.02 13.9 0.0 0.059 12.4 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin Hpr_kinase_C PF07475.7 KFX91128.1 - 0.02 14.1 0.1 4 6.7 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_17 PF13207.1 KFX91128.1 - 0.059 14.1 0.0 0.21 12.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KFX91128.1 - 0.075 12.7 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 KFX91128.1 - 0.077 12.6 0.1 0.23 11.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain DUF552 PF04472.7 KFX91128.1 - 0.1 12.5 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF552) Sigma54_activ_2 PF14532.1 KFX91128.1 - 0.15 12.0 0.0 0.43 10.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Ank_2 PF12796.2 KFX91129.1 - 4.6e-26 90.9 3.2 5.1e-15 55.5 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFX91129.1 - 1.8e-20 71.6 5.1 1e-05 25.0 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KFX91129.1 - 1.7e-15 57.0 0.1 5.5e-08 33.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX91129.1 - 1.8e-15 55.4 0.1 0.0025 17.8 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KFX91129.1 - 2.5e-10 40.2 3.2 0.00036 20.6 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DUF676 PF05057.9 KFX91129.1 - 0.0035 16.6 0.0 0.0058 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) FAD_binding_8 PF08022.7 KFX91130.1 - 2.7e-22 78.6 0.0 5.7e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KFX91130.1 - 8.4e-21 74.4 0.0 1.4e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KFX91130.1 - 1e-16 61.1 8.8 1e-16 61.1 6.1 2.2 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KFX91130.1 - 6.8e-06 26.1 0.0 2e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain F-box-like PF12937.2 KFX91131.1 - 0.0023 17.6 0.2 1.1 9.0 0.0 2.3 2 0 0 2 2 2 2 F-box-like F-box-like_2 PF13013.1 KFX91131.1 - 0.038 13.7 0.5 0.21 11.2 0.4 2.1 1 1 0 1 1 1 0 F-box-like domain AhpC-TSA PF00578.16 KFX91142.1 - 2.6e-25 88.5 0.0 3.6e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KFX91142.1 - 7.4e-16 57.9 0.0 1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 KFX91142.1 - 5.1e-05 23.1 0.0 0.00023 21.0 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Vps51 PF08700.6 KFX91143.1 - 1.6e-10 40.6 0.0 9.5e-10 38.1 0.0 2.3 2 0 0 2 2 2 1 Vps51/Vps67 UCR_Fe-S_N PF10399.4 KFX91143.1 - 0.099 11.8 0.2 0.24 10.5 0.1 1.7 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal BTB PF00651.26 KFX91144.1 - 3.8e-10 39.7 0.0 1.4e-09 37.8 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain Glyco_hydro_92 PF07971.7 KFX91144.1 - 0.0019 16.9 0.0 0.0026 16.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DUF705 PF05152.7 KFX91144.1 - 0.078 11.9 0.0 0.24 10.3 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF705) Pro_isomerase PF00160.16 KFX91145.1 - 4.1e-44 150.5 0.1 6.3e-44 149.8 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 KFX91145.1 - 2e-07 30.5 5.9 0.0015 18.1 0.0 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFX91145.1 - 1.6e-05 24.4 3.9 0.00076 19.2 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFX91145.1 - 0.0019 17.7 1.8 0.0088 15.6 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFX91145.1 - 0.28 11.9 6.1 0.65 10.7 2.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFX91145.1 - 0.61 10.8 9.8 0.15 12.8 1.2 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat BP28CT PF08146.7 KFX91148.1 - 4.6e-36 123.8 0.2 4.6e-36 123.8 0.1 3.3 3 1 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 KFX91148.1 - 2.4e-26 92.0 0.0 2.4e-26 92.0 0.0 5.0 4 1 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 KFX91148.1 - 0.00025 20.8 7.0 0.28 11.3 0.1 6.1 5 0 0 5 5 5 2 HEAT repeat EF-hand_4 PF12763.2 KFX91148.1 - 0.015 14.9 0.0 0.046 13.4 0.0 1.7 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand HEAT_2 PF13646.1 KFX91148.1 - 0.58 10.4 26.7 0.47 10.7 0.1 7.4 8 0 0 8 8 8 0 HEAT repeats DHBP_synthase PF00926.14 KFX91158.1 - 3e-18 65.7 0.0 3.4e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase SDH_alpha PF03313.10 KFX91158.1 - 0.051 12.5 0.2 0.074 12.0 0.2 1.2 1 0 0 1 1 1 0 Serine dehydratase alpha chain Cellulase PF00150.13 KFX91159.1 - 7.4e-20 71.2 2.8 8.1e-20 71.1 1.5 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KFX91159.1 - 2.3e-11 43.1 13.0 5.5e-11 41.9 9.0 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain DNMT1-RFD PF12047.3 KFX91159.1 - 1.9e-05 24.3 0.5 6.9e-05 22.5 0.2 1.8 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain Cellulase-like PF12876.2 KFX91159.1 - 0.00075 19.9 0.0 0.0017 18.7 0.0 1.7 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 KFX91159.1 - 0.0066 15.3 0.1 0.011 14.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 KFX91159.1 - 0.02 14.0 0.1 0.038 13.1 0.1 1.4 1 0 0 1 1 1 0 Beta-galactosidase Glyco_hydro_10 PF00331.15 KFX91159.1 - 0.046 12.7 3.4 0.035 13.1 0.3 2.3 2 1 1 3 3 3 0 Glycosyl hydrolase family 10 adh_short PF00106.20 KFX91160.1 - 1.2e-26 93.5 2.5 1.6e-26 93.1 1.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX91160.1 - 1.8e-26 93.4 0.1 2.1e-26 93.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX91160.1 - 1.4e-10 41.1 1.2 1.9e-10 40.6 0.8 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFX91160.1 - 0.00062 19.2 0.1 0.0011 18.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX91160.1 - 0.0017 18.3 1.2 0.022 14.7 0.9 2.1 1 1 0 1 1 1 1 NADH(P)-binding Zn_clus PF00172.13 KFX91161.1 - 1.1e-07 31.6 10.9 1.9e-07 30.8 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.7 KFX91161.1 - 0.021 14.6 1.9 0.052 13.3 1.3 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat HypA PF01155.14 KFX91161.1 - 0.8 9.4 4.7 1.4 8.6 3.3 1.4 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Oxidored_FMN PF00724.15 KFX91162.1 - 2.4e-95 319.3 0.0 2.8e-95 319.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family KRTDAP PF15200.1 KFX91163.1 - 0.076 12.7 0.1 0.15 11.8 0.0 1.5 1 1 1 2 2 2 0 Keratinocyte differentiation-associated Dehydratase_hem PF13816.1 KFX91163.1 - 0.1 11.6 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Haem-containing dehydratase ADH_zinc_N PF00107.21 KFX91164.1 - 2.4e-16 59.4 0.0 4.4e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX91164.1 - 2.1e-08 33.8 0.0 0.0014 18.3 0.0 2.5 2 0 0 2 2 2 2 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.14 KFX91164.1 - 0.0027 16.8 0.0 0.0047 16.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.15 KFX91164.1 - 0.072 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ELFV_dehydrog PF00208.16 KFX91164.1 - 0.15 11.5 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase PNGaseA PF12222.3 KFX91165.1 - 2.6e-140 468.0 0.1 3.2e-140 467.7 0.1 1.0 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A RNA_pol_Rpb1_1 PF04997.7 KFX91170.1 - 3e-39 135.2 0.6 3.6e-39 134.9 0.4 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 PPR_2 PF13041.1 KFX91171.1 - 1e-10 41.4 0.0 0.00045 20.1 0.0 3.8 3 1 0 3 3 3 2 PPR repeat family PPR_3 PF13812.1 KFX91171.1 - 7.9e-06 25.7 0.3 0.72 10.2 0.0 4.7 4 1 1 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.15 KFX91171.1 - 0.0026 17.5 0.8 10 6.3 0.0 3.9 4 0 0 4 4 4 2 PPR repeat Peptidase_M20 PF01546.23 KFX91172.1 - 4.4e-32 111.1 0.0 7e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFX91172.1 - 2.3e-15 56.2 0.0 4.2e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF761 PF05553.6 KFX91172.1 - 0.094 12.0 0.2 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 Cotton fibre expressed protein Peptidase_M1 PF01433.15 KFX91173.1 - 5.6e-69 233.0 0.0 7.2e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KFX91173.1 - 4.2e-42 143.1 0.0 7.2e-42 142.3 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KFX91173.1 - 1.2e-17 64.1 0.4 2e-17 63.4 0.3 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 KFX91173.1 - 0.11 12.5 2.3 0.52 10.3 1.6 2.1 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Uds1 PF15456.1 KFX91176.1 - 1.4e-34 118.6 4.9 1.4e-34 118.6 3.4 1.8 2 0 0 2 2 2 1 Up-regulated During Septation Wbp11 PF09429.5 KFX91176.1 - 0.02 14.8 0.1 0.061 13.3 0.1 1.7 1 0 0 1 1 1 0 WW domain binding protein 11 Adap_comp_sub PF00928.16 KFX91177.1 - 1.4e-57 194.7 0.0 2.3e-57 194.0 0.0 1.3 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KFX91177.1 - 0.017 14.8 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain DUF4536 PF15055.1 KFX91178.1 - 0.084 12.9 0.9 0.084 12.9 0.6 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4536) ECR1_N PF14382.1 KFX91179.1 - 8.8e-11 40.9 0.2 2.4e-10 39.4 0.0 1.9 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 KFX91179.1 - 0.0088 16.1 0.4 0.16 12.0 0.0 3.1 4 0 0 4 4 4 1 S1 RNA binding domain EXOSC1 PF10447.4 KFX91179.1 - 0.085 12.8 0.4 1.3 9.0 0.0 2.7 2 1 0 2 2 2 0 Exosome component EXOSC1/CSL4 DUF4588 PF15251.1 KFX91180.1 - 0.02 14.9 7.3 0.059 13.3 5.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) SOG2 PF10428.4 KFX91180.1 - 8.5 4.9 7.9 29 3.1 3.7 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein SNF2_N PF00176.18 KFX91181.1 - 3.7e-82 275.4 0.1 6.8e-82 274.6 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 KFX91181.1 - 5e-44 148.8 3.0 1.5e-43 147.2 2.1 1.9 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 KFX91181.1 - 8.2e-36 122.8 0.5 8.2e-36 122.8 0.3 4.8 5 0 0 5 5 5 1 HAND Helicase_C PF00271.26 KFX91181.1 - 6.5e-15 54.7 0.0 2.3e-14 52.9 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX91181.1 - 1.2e-09 38.2 0.2 1.9e-08 34.3 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFX91181.1 - 6.8e-06 25.6 0.0 1.6e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.26 KFX91181.1 - 0.0035 17.3 0.0 0.067 13.2 0.0 3.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain DEAD_2 PF06733.10 KFX91181.1 - 0.027 13.8 0.1 0.062 12.6 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.1 KFX91181.1 - 0.044 13.6 0.1 0.17 11.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KFX91181.1 - 0.14 12.2 1.1 0.92 9.6 0.1 3.0 2 1 0 2 2 2 0 AAA domain Zn_clus PF00172.13 KFX91182.1 - 0.012 15.5 10.7 0.021 14.7 7.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain EHN PF06441.7 KFX91183.1 - 6.9e-26 90.3 0.4 1.1e-25 89.7 0.3 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KFX91183.1 - 1.2e-08 35.1 0.1 2.3e-08 34.1 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX91183.1 - 5.1e-07 29.4 0.0 8.3e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF4066 PF13278.1 KFX91184.1 - 1.4e-23 82.9 0.0 2e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KFX91184.1 - 2e-10 40.3 0.0 3.3e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family MFS_1 PF07690.11 KFX91185.1 - 1e-31 109.9 37.4 1e-31 109.9 26.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily SBP_bac_11 PF13531.1 KFX91185.1 - 0.093 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Catalase PF00199.14 KFX91186.1 - 2.2e-173 576.3 0.7 2.6e-173 576.1 0.5 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KFX91186.1 - 3.5e-13 49.2 0.0 1.3e-12 47.3 0.0 2.1 2 0 0 2 2 2 1 Catalase-related immune-responsive Fungal_trans PF04082.13 KFX91187.1 - 2.8e-15 55.8 0.2 5e-15 55.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX91187.1 - 1.2e-08 34.7 11.6 2.3e-08 33.8 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.14 KFX91188.1 - 1.2e-51 175.6 0.0 1.6e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFX91188.1 - 2.6e-34 118.6 0.0 4.1e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KFX91188.1 - 6.7e-05 21.9 1.0 0.2 10.4 0.6 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KFX91188.1 - 0.0027 16.6 0.1 0.024 13.5 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KFX91188.1 - 0.0083 15.0 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 KFX91188.1 - 0.02 13.5 0.3 0.028 13.0 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 KFX91188.1 - 0.027 14.3 0.0 0.05 13.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX91188.1 - 0.03 14.3 0.5 0.07 13.1 0.4 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KFX91188.1 - 0.036 14.1 0.0 1.3 9.0 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX91188.1 - 0.08 12.7 0.0 0.74 9.5 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 KFX91188.1 - 0.21 10.6 0.6 0.37 9.8 0.1 1.6 2 0 0 2 2 2 0 Thi4 family Glyco_hydro_75 PF07335.6 KFX91199.1 - 9.8e-49 165.2 0.3 1.3e-48 164.8 0.2 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 SRP1_TIP1 PF00660.12 KFX91199.1 - 0.0074 16.0 0.0 0.023 14.5 0.0 1.7 2 0 0 2 2 2 1 Seripauperin and TIP1 family Pectate_lyase_3 PF12708.2 KFX91200.1 - 7.3e-42 144.0 24.6 3e-32 112.5 8.2 3.2 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KFX91200.1 - 0.045 13.2 2.1 0.17 11.3 0.0 2.6 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase Sugar_tr PF00083.19 KFX91201.1 - 3.3e-79 266.5 22.6 3.9e-79 266.3 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX91201.1 - 3.9e-29 101.4 17.0 3.9e-29 101.4 11.8 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX91201.1 - 0.00011 20.7 3.8 0.00011 20.7 2.6 2.6 2 2 0 2 2 2 1 MFS/sugar transport protein Pox_A14 PF05767.7 KFX91201.1 - 0.028 14.3 0.7 0.17 11.8 0.5 2.3 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 UNC-93 PF05978.11 KFX91201.1 - 0.61 9.5 13.6 0.3 10.5 2.2 2.6 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 EntA_Immun PF08951.5 KFX91202.1 - 0.0036 17.4 0.7 0.0098 16.0 0.5 1.7 1 0 0 1 1 1 1 Enterocin A Immunity DUF3647 PF12363.3 KFX91202.1 - 0.049 13.7 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Phage protein RRM_1 PF00076.17 KFX91203.1 - 2.9e-45 151.7 0.0 2.2e-13 49.6 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX91203.1 - 7.5e-38 128.3 0.0 7.9e-11 41.7 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX91203.1 - 2.5e-23 81.6 0.1 3.2e-06 26.8 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFX91203.1 - 0.0008 19.1 0.0 1.1 9.0 0.0 2.8 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif TPR_14 PF13428.1 KFX91203.1 - 0.71 10.6 8.0 9.3 7.1 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Ribosomal_L22 PF00237.14 KFX91204.1 - 6.3e-17 61.4 0.2 3.8e-15 55.7 0.1 2.4 1 1 0 1 1 1 1 Ribosomal protein L22p/L17e DAO PF01266.19 KFX91205.1 - 6.1e-21 74.7 0.5 5.6e-15 55.1 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX91205.1 - 0.03 14.3 0.1 0.07 13.1 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF3425 PF11905.3 KFX91206.1 - 1.6e-32 112.2 1.6 3.1e-32 111.2 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) PI31_Prot_N PF11566.3 KFX91214.1 - 1.3e-36 125.5 0.0 2.4e-36 124.6 0.0 1.5 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal adh_short PF00106.20 KFX91214.1 - 4.5e-33 114.5 0.0 9.9e-33 113.4 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase DUF4267 PF14087.1 KFX91214.1 - 2.4e-16 59.3 3.2 4.2e-16 58.5 2.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) PI31_Prot_C PF08577.6 KFX91214.1 - 6.2e-14 52.3 18.0 6.2e-14 52.3 12.4 3.0 3 0 0 3 3 3 1 PI31 proteasome regulator adh_short_C2 PF13561.1 KFX91214.1 - 2.3e-13 50.4 0.0 4.1e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX91214.1 - 3.6e-12 46.3 0.4 7.5e-12 45.2 0.0 1.7 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 KFX91214.1 - 0.012 15.3 0.2 0.027 14.2 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase GATA PF00320.22 KFX91215.1 - 0.15 11.4 7.1 2.4 7.5 0.0 3.3 3 1 0 3 3 3 0 GATA zinc finger DZR PF12773.2 KFX91215.1 - 0.16 11.8 4.7 0.83 9.5 0.4 3.2 2 1 0 2 2 2 0 Double zinc ribbon zf-B_box PF00643.19 KFX91215.1 - 1.1 9.2 9.0 30 4.6 0.1 3.6 2 1 0 2 2 2 0 B-box zinc finger GAS PF13851.1 KFX91216.1 - 0.0074 15.5 0.3 0.0087 15.2 0.2 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding AAA_27 PF13514.1 KFX91216.1 - 0.015 13.0 1.5 0.016 12.9 1.0 1.0 1 0 0 1 1 1 0 AAA domain Uds1 PF15456.1 KFX91216.1 - 0.048 13.6 0.6 0.051 13.5 0.4 1.1 1 0 0 1 1 1 0 Up-regulated During Septation BRO1 PF03097.13 KFX91216.1 - 0.083 11.6 0.4 0.088 11.5 0.3 1.0 1 0 0 1 1 1 0 BRO1-like domain Sec2p PF06428.6 KFX91216.1 - 0.23 11.3 4.1 0.27 11.1 2.3 1.5 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p DUF1542 PF07564.6 KFX91216.1 - 0.63 10.0 5.0 0.99 9.4 3.5 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) DUF3716 PF12511.3 KFX91217.1 - 2 8.0 9.6 5 6.8 6.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) WD40 PF00400.27 KFX91225.1 - 1.7e-48 160.8 22.2 9e-10 38.0 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KFX91225.1 - 0.0001 22.0 0.0 0.048 13.3 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Atg14 PF10186.4 KFX91225.1 - 1.6 7.6 4.4 2.5 6.9 3.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ank_2 PF12796.2 KFX91228.1 - 1.2e-25 89.6 0.0 1.1e-09 38.4 0.0 4.9 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFX91228.1 - 1e-18 67.2 4.4 1.4e-06 28.6 0.0 7.1 6 2 2 8 8 8 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX91228.1 - 1.9e-16 59.6 7.9 0.074 13.3 0.0 8.6 7 2 2 9 9 9 4 Ankyrin repeats (many copies) Ank PF00023.25 KFX91228.1 - 3.7e-15 54.8 9.4 0.0085 15.8 0.0 7.6 8 1 1 9 9 9 4 Ankyrin repeat Ank_3 PF13606.1 KFX91228.1 - 1.2e-14 52.9 3.3 0.17 12.2 0.0 7.3 7 0 0 7 7 7 4 Ankyrin repeat Transketolase_N PF00456.16 KFX91229.1 - 1.3e-147 490.9 0.3 1.8e-147 490.5 0.2 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 KFX91229.1 - 1.5e-44 151.6 0.0 2.4e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KFX91229.1 - 4.1e-13 49.3 0.0 8.2e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 KFX91229.1 - 7.5e-05 21.7 0.1 0.0002 20.4 0.1 1.7 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Scm3 PF10384.4 KFX91229.1 - 0.17 11.4 0.1 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Centromere protein Scm3 WD40 PF00400.27 KFX91236.1 - 6.7e-06 25.7 4.4 0.18 11.7 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Isochorismatase PF00857.15 KFX91237.1 - 2.2e-28 99.3 0.0 3.8e-28 98.5 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family MARVEL PF01284.18 KFX91238.1 - 6.5e-05 22.7 11.7 0.00055 19.7 8.2 1.9 1 1 0 1 1 1 1 Membrane-associating domain CytB6-F_Fe-S PF08802.5 KFX91238.1 - 0.0091 15.9 0.6 0.036 14.0 0.4 2.0 1 0 0 1 1 1 1 Cytochrome B6-F complex Fe-S subunit DUF2189 PF09955.4 KFX91238.1 - 0.054 13.4 12.0 2.1 8.2 0.1 2.7 2 1 0 2 2 2 0 Predicted integral membrane protein (DUF2189) 7TMR-DISM_7TM PF07695.6 KFX91238.1 - 1.4 8.5 9.5 0.51 9.9 3.3 1.9 2 0 0 2 2 2 0 7TM diverse intracellular signalling RDD PF06271.7 KFX91238.1 - 7.5 6.4 9.6 4.7 7.1 0.6 2.5 2 1 0 2 2 2 0 RDD family DUF1919 PF08942.5 KFX91248.1 - 0.1 11.9 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1919) Mu-like_Com PF10122.4 KFX91248.1 - 0.11 11.5 0.0 0.35 9.9 0.0 1.8 1 0 0 1 1 1 0 Mu-like prophage protein Com LSM PF01423.17 KFX91249.1 - 8.3e-15 54.0 0.3 1.1e-14 53.7 0.2 1.1 1 0 0 1 1 1 1 LSM domain AA_permease PF00324.16 KFX91250.1 - 2.7e-122 408.5 44.0 3.2e-122 408.2 30.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFX91250.1 - 3.2e-28 98.4 49.0 4.3e-28 98.0 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease Metallophos PF00149.23 KFX91251.1 - 3.9e-07 29.6 3.7 2.1e-06 27.2 2.5 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2413 PF10310.4 KFX91253.1 - 8e-138 459.9 0.0 9.2e-138 459.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 KFX91253.1 - 0.01 15.8 0.3 0.04 13.9 0.1 2.0 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain Pkinase PF00069.20 KFX91254.1 - 3.5e-69 232.8 0.0 5.3e-69 232.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX91254.1 - 2.6e-31 108.6 0.0 6.6e-30 104.0 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX91254.1 - 0.0048 15.9 0.8 1.4 7.8 0.0 2.7 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 KFX91254.1 - 0.0071 16.1 0.0 0.16 11.6 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 KFX91254.1 - 0.046 13.0 0.2 0.1 11.9 0.2 1.6 1 1 0 1 1 1 0 RIO1 family Fungal_trans PF04082.13 KFX91255.1 - 4.9e-05 22.3 2.6 0.00087 18.2 1.8 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX91255.1 - 0.00012 21.8 10.6 0.00024 20.9 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Protocadherin PF08374.6 KFX91255.1 - 0.075 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Protocadherin Dickkopf_N PF04706.7 KFX91255.1 - 0.38 10.9 8.1 0.84 9.8 5.6 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region MFS_1 PF07690.11 KFX91256.1 - 5.5e-19 68.0 26.8 1.2e-12 47.2 1.6 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily CFEM PF05730.6 KFX91258.1 - 3.3e-11 42.8 14.1 5.1e-11 42.2 9.8 1.3 1 0 0 1 1 1 1 CFEM domain GRIM-19 PF06212.7 KFX91260.1 - 1.6e-21 76.3 0.0 3.1e-21 75.4 0.0 1.4 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.16 KFX91261.1 - 3.5e-34 118.0 0.0 1.4e-24 86.7 0.0 2.4 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase SR-25 PF10500.4 KFX91261.1 - 0.0062 16.0 4.1 0.0062 16.0 2.8 2.4 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein Acetyltransf_7 PF13508.1 KFX91262.1 - 3.4e-06 27.1 0.1 5.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX91262.1 - 1.8e-05 24.6 0.2 5.4e-05 23.1 0.2 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFX91262.1 - 0.00018 21.5 0.1 0.00033 20.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFX91262.1 - 0.00091 18.9 0.1 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein DUF3472 PF11958.3 KFX91263.1 - 9.2e-14 52.1 1.5 1.2e-13 51.8 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Melibiase PF02065.13 KFX91264.1 - 1.6e-10 40.2 0.0 2.8e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Melibiase Ricin_B_lectin PF00652.17 KFX91264.1 - 1.6e-09 37.8 4.0 3.5e-09 36.7 2.8 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Fig1 PF12351.3 KFX91265.1 - 2.1e-54 184.1 6.5 2.1e-54 184.1 4.5 2.1 1 1 1 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 KFX91265.1 - 1.8e-08 34.2 12.0 2.3e-08 33.8 8.3 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF1970 PF09301.5 KFX91265.1 - 0.017 15.1 0.2 0.059 13.4 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) SPASM PF13186.1 KFX91265.1 - 0.11 12.9 0.1 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 Iron-sulfur cluster-binding domain DUF898 PF05987.8 KFX91265.1 - 0.21 10.4 13.1 0.015 14.2 4.8 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) DUF4064 PF13273.1 KFX91265.1 - 1.6 8.8 15.4 3.2 7.9 0.8 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) HSF_DNA-bind PF00447.12 KFX91266.1 - 5.1e-38 129.4 0.8 1.1e-37 128.3 0.5 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 KFX91266.1 - 1.3e-19 70.2 0.1 2.5e-19 69.3 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Cu-oxidase_2 PF07731.9 KFX91275.1 - 5.6e-35 119.8 1.3 6.5e-35 119.6 0.9 1.1 1 0 0 1 1 1 1 Multicopper oxidase HSP70 PF00012.15 KFX91277.1 - 8.4e-194 644.8 3.6 9.5e-194 644.6 2.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFX91277.1 - 1.4e-16 60.0 0.2 1.3e-15 56.8 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KFX91277.1 - 8.8e-05 22.2 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 KFX91277.1 - 0.014 14.2 0.7 0.1 11.3 0.2 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.1 KFX91277.1 - 0.018 14.8 2.2 0.85 9.4 0.1 3.1 2 1 0 2 2 2 0 Cell division protein FtsA Bromodomain PF00439.20 KFX91278.1 - 7e-31 105.9 0.9 1.2e-14 53.9 0.1 2.4 2 0 0 2 2 2 2 Bromodomain SpoVG PF04026.7 KFX91278.1 - 0.16 12.0 0.2 0.88 9.6 0.0 2.2 2 0 0 2 2 2 0 SpoVG CKS PF01111.14 KFX91279.1 - 3.2e-36 122.9 0.7 4.1e-36 122.6 0.5 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit APC_15aa PF05972.6 KFX91279.1 - 0.1 12.5 1.9 1.1 9.4 0.2 2.4 2 0 0 2 2 2 0 APC 15 residue motif ERO1 PF04137.10 KFX91281.1 - 2.3e-134 447.9 0.0 4.2e-134 447.0 0.0 1.4 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Pal1 PF08316.6 KFX91282.1 - 5.3e-05 23.6 0.1 0.00012 22.4 0.1 1.6 1 0 0 1 1 1 1 Pal1 cell morphology protein HVSL PF09749.4 KFX91283.1 - 8.2e-78 260.7 0.0 9.7e-78 260.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein MFS_1 PF07690.11 KFX91286.1 - 4.3e-19 68.4 34.0 2.5e-18 65.9 22.5 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFX91286.1 - 6.3e-09 34.5 7.6 6.3e-09 34.5 5.2 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sex_peptide PF08138.6 KFX91286.1 - 0.29 11.0 3.0 2.4 8.0 0.0 3.3 3 0 0 3 3 3 0 Sex peptide (SP) family RTA1 PF04479.8 KFX91288.1 - 8.7e-43 146.4 9.1 8.7e-43 146.4 6.3 1.7 1 1 1 2 2 2 1 RTA1 like protein DUF4271 PF14093.1 KFX91288.1 - 8.4 6.0 17.3 3.4 7.3 4.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4271) DUF1993 PF09351.5 KFX91289.1 - 1.1e-50 171.7 0.0 1.2e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) FliG_M PF14841.1 KFX91289.1 - 0.052 13.5 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 FliG middle domain Oxidored_molyb PF00174.14 KFX91290.1 - 1.6e-54 183.8 0.0 2.3e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KFX91290.1 - 1.4e-30 105.5 0.7 2.6e-30 104.7 0.5 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 KFX91290.1 - 2.4e-12 46.4 0.0 4.4e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Hus1 PF04005.7 KFX91303.1 - 2.8e-90 302.2 0.0 3.9e-90 301.7 0.0 1.1 1 0 0 1 1 1 1 Hus1-like protein E1-E2_ATPase PF00122.15 KFX91316.1 - 1.7e-64 217.0 2.6 1.7e-64 217.0 1.8 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFX91316.1 - 1.9e-32 112.2 9.4 1.9e-32 112.2 6.5 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFX91316.1 - 3.2e-29 102.9 0.0 2.7e-27 96.6 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFX91316.1 - 4.6e-17 61.7 0.0 1.8e-16 59.8 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KFX91316.1 - 4.6e-15 54.8 0.0 1.2e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFX91316.1 - 1.2e-13 51.7 0.0 2.5e-13 50.6 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFX91316.1 - 0.00043 19.9 0.6 0.001 18.7 0.4 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ytp1 PF10355.4 KFX91317.1 - 3.2e-65 220.0 8.8 6.5e-65 219.0 6.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KFX91317.1 - 1.3e-25 88.9 5.2 1.7e-25 88.5 1.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) GAF PF01590.21 KFX91320.1 - 0.013 15.5 0.0 0.025 14.7 0.0 1.6 1 1 0 1 1 1 0 GAF domain GAF_3 PF13492.1 KFX91320.1 - 0.026 14.6 0.0 0.075 13.1 0.0 1.8 1 1 0 1 1 1 0 GAF domain ICL PF00463.16 KFX91320.1 - 0.13 10.4 0.0 0.16 10.1 0.0 1.1 1 0 0 1 1 1 0 Isocitrate lyase family HATPase_c PF02518.21 KFX91321.1 - 4.3e-23 81.1 0.0 1.1e-22 79.8 0.0 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KFX91321.1 - 6e-15 55.2 0.0 1.7e-13 50.5 0.0 2.4 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KFX91321.1 - 4.7e-07 29.7 0.0 1.3e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain MEDS PF14417.1 KFX91321.1 - 0.00041 19.4 0.3 0.18 10.8 0.0 2.3 2 0 0 2 2 2 2 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Spidroin_MaSp PF11260.3 KFX91321.1 - 5.4 7.1 7.6 5 7.2 0.0 3.7 5 0 0 5 5 5 0 Major ampullate spidroin 1 and 2 Ecl1 PF12855.2 KFX91322.1 - 8.4e-11 40.9 1.3 1.2e-10 40.4 0.9 1.2 1 0 0 1 1 1 1 Life-span regulatory factor DUF329 PF03884.9 KFX91322.1 - 0.045 13.3 2.6 0.085 12.4 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF329) C1_1 PF00130.17 KFX91322.1 - 0.056 13.1 1.6 0.15 11.8 1.2 1.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-MYND PF01753.13 KFX91322.1 - 0.14 12.0 1.1 0.24 11.3 0.8 1.3 1 0 0 1 1 1 0 MYND finger DUF581 PF04570.9 KFX91322.1 - 0.32 10.3 3.0 1.4 8.2 2.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF581) MFS_1 PF07690.11 KFX91323.1 - 8.8e-25 87.1 45.2 4.8e-19 68.2 9.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX91323.1 - 4.6e-12 45.2 0.1 4.6e-12 45.2 0.1 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KFX91323.1 - 0.00035 19.1 20.2 0.0048 15.3 3.2 4.2 2 2 2 4 4 4 2 MFS/sugar transport protein RRP7 PF12923.2 KFX91324.1 - 4.2e-16 59.1 2.2 4.2e-16 59.1 1.5 1.8 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) Rad51 PF08423.6 KFX91325.1 - 5.2e-122 405.6 0.0 7.1e-122 405.2 0.0 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.16 KFX91325.1 - 1.7e-12 47.0 0.0 2.1e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.1 KFX91325.1 - 2.3e-09 36.9 0.0 3.5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KFX91325.1 - 7.1e-08 31.8 0.0 1.5e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 KaiC HHH_5 PF14520.1 KFX91325.1 - 0.012 15.7 3.2 0.016 15.3 0.4 2.5 3 0 0 3 3 3 0 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.10 KFX91325.1 - 0.048 13.0 0.4 0.12 11.7 0.3 1.7 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain DnaB_C PF03796.10 KFX91325.1 - 0.055 12.3 0.0 0.23 10.3 0.0 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Ald_Xan_dh_C PF01315.17 KFX91325.1 - 0.094 12.8 0.0 5.3 7.1 0.0 2.5 2 0 0 2 2 2 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain AAA PF00004.24 KFX91325.1 - 0.1 12.8 0.4 1.3 9.2 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-CCHC PF00098.18 KFX91326.1 - 1.6e-40 135.1 54.3 3.5e-07 29.8 1.3 7.3 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 KFX91326.1 - 1.8e-09 37.0 45.4 0.0015 18.1 0.5 7.5 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 KFX91326.1 - 1.1e-05 25.0 41.4 0.88 9.3 0.3 7.1 4 2 2 6 6 6 5 Zinc knuckle zf-CCHC_5 PF14787.1 KFX91326.1 - 0.0019 17.6 4.4 0.0019 17.6 3.1 6.5 4 3 2 6 6 6 3 GAG-polyprotein viral zinc-finger Sporozoite_P67 PF05642.6 KFX91326.1 - 0.15 9.8 1.6 0.19 9.5 1.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAD_binding_3 PF01494.14 KFX91327.1 - 8.2e-15 54.7 0.1 6.1e-07 28.8 0.0 3.1 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KFX91327.1 - 5.7e-05 23.0 0.1 0.00012 21.9 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFX91327.1 - 0.015 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFX91327.1 - 0.07 12.0 0.3 0.15 10.9 0.2 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 KFX91327.1 - 0.097 12.2 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sugar_tr PF00083.19 KFX91328.1 - 2.1e-73 247.4 14.1 2.3e-73 247.2 9.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX91328.1 - 3.4e-29 101.6 16.2 4.9e-29 101.1 11.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFX91328.1 - 7.2e-06 24.6 15.7 0.00087 17.7 0.2 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 KFX91328.1 - 0.00055 18.2 0.4 0.00055 18.2 0.3 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MTP18 PF10558.4 KFX91329.1 - 7.5e-63 210.8 0.3 9.1e-63 210.6 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) BatD PF13584.1 KFX91330.1 - 0.043 12.4 0.1 0.05 12.2 0.1 1.0 1 0 0 1 1 1 0 Oxygen tolerance DUF4381 PF14316.1 KFX91330.1 - 0.043 13.9 0.2 0.059 13.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) FixQ PF05545.6 KFX91330.1 - 0.061 12.9 0.2 0.096 12.3 0.2 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Tbf5 PF06331.7 KFX91331.1 - 9.9e-26 89.3 0.3 1.1e-25 89.2 0.2 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 2OG-FeII_Oxy_2 PF13532.1 KFX91332.1 - 2.7e-27 95.8 0.0 6.5e-27 94.6 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.15 KFX91332.1 - 1e-22 80.9 0.2 5e-18 65.6 0.0 2.6 3 0 0 3 3 3 2 Isochorismatase family GST_C_2 PF13410.1 KFX91332.1 - 1.2e-09 37.9 0.9 2.7e-09 36.7 0.6 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFX91332.1 - 3.7e-07 30.5 0.0 1.1e-06 29.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFX91332.1 - 1.6e-06 28.0 0.0 3.9e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain 2OG-FeII_Oxy PF03171.15 KFX91332.1 - 0.015 15.5 0.0 0.03 14.6 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily ECH PF00378.15 KFX91333.1 - 4.3e-42 143.9 0.4 9.2e-42 142.8 0.3 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pkinase PF00069.20 KFX91336.1 - 1e-73 247.7 0.0 1.3e-73 247.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX91336.1 - 2.3e-31 108.8 0.0 3.3e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX91336.1 - 0.00085 18.3 0.0 0.0016 17.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFX91336.1 - 0.0029 16.6 0.1 0.0051 15.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFX91336.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KFX91336.1 - 0.059 12.2 0.0 0.09 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RNA_pol_Rpb1_5 PF04998.12 KFX91338.1 - 1.2e-89 300.2 0.1 1.7e-89 299.7 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_3 PF04983.13 KFX91338.1 - 1.6e-39 135.1 0.0 3.4e-39 134.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KFX91338.1 - 2.3e-29 101.3 0.2 6.4e-29 99.8 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Phlebovirus_NSM PF07246.6 KFX91339.1 - 0.041 13.0 0.4 0.046 12.8 0.3 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF4232 PF14016.1 KFX91339.1 - 0.1 12.2 1.3 0.13 11.9 0.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4232) AA_permease_2 PF13520.1 KFX91341.1 - 9.7e-38 129.8 53.2 1.4e-37 129.2 36.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFX91341.1 - 7.2e-12 44.3 43.8 1.1e-11 43.7 30.4 1.2 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_9 PF13527.1 KFX91342.1 - 9.9e-05 22.1 0.0 0.61 9.9 0.0 2.3 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFX91342.1 - 0.00012 22.1 0.0 0.00034 20.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX91342.1 - 0.00024 21.0 0.0 0.00045 20.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFX91342.1 - 0.0047 17.0 0.0 0.017 15.2 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain AA_permease_2 PF13520.1 KFX91344.1 - 1.6e-58 198.2 45.7 2e-58 197.9 31.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFX91344.1 - 2e-32 112.2 36.1 2.5e-32 111.8 25.0 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 KFX91345.1 - 1.6e-07 30.3 18.8 1.6e-07 30.3 13.0 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.14 KFX91347.1 - 1.2e-06 27.8 0.2 7.2e-06 25.2 0.2 1.9 1 1 0 1 1 1 1 FAD binding domain Pkr1 PF08636.5 KFX91348.1 - 5.2e-27 93.7 5.5 6.4e-27 93.4 3.8 1.1 1 0 0 1 1 1 1 ER protein Pkr1 FHIPEP PF00771.15 KFX91348.1 - 0.032 12.5 0.0 0.036 12.4 0.0 1.0 1 0 0 1 1 1 0 FHIPEP family OAD_gamma PF04277.8 KFX91348.1 - 0.12 12.7 0.0 0.26 11.6 0.0 1.5 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Cys_Met_Meta_PP PF01053.15 KFX91353.1 - 6e-139 462.6 0.2 6.9e-139 462.4 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KFX91353.1 - 8.8e-08 31.5 1.5 1.7e-07 30.6 1.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 KFX91353.1 - 1.8e-06 27.1 0.3 2.8e-06 26.5 0.2 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KFX91353.1 - 2.4e-06 26.5 0.7 4.1e-06 25.7 0.5 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KFX91353.1 - 4e-05 22.9 0.6 7.7e-05 21.9 0.4 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 KFX91353.1 - 0.014 14.1 0.3 0.022 13.4 0.2 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein APG5 PF04106.7 KFX91364.1 - 1.7e-37 128.8 0.0 4.3e-37 127.5 0.0 1.6 1 1 0 1 1 1 1 Autophagy protein Apg5 Zn_clus PF00172.13 KFX91365.1 - 9e-07 28.7 9.7 1.6e-06 27.9 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GBP_repeat PF02526.9 KFX91365.1 - 0.18 11.2 1.1 3.6 7.0 0.0 2.6 2 0 0 2 2 2 0 Glycophorin-binding protein Pro_CA PF00484.14 KFX91368.1 - 2.9e-16 59.8 0.0 3.6e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Ribosomal_L7Ae PF01248.21 KFX91369.1 - 1.7e-21 75.5 0.7 3e-21 74.7 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PNP_UDP_1 PF01048.15 KFX91373.1 - 0.0013 17.7 0.1 0.73 8.7 0.0 2.4 2 1 0 2 2 2 2 Phosphorylase superfamily Cas_VVA1548 PF09652.5 KFX91373.1 - 0.013 15.4 0.0 0.096 12.7 0.0 2.3 2 0 0 2 2 2 0 Putative CRISPR-associated protein (Cas_VVA1548) Cu_bind_like PF02298.12 KFX91373.1 - 0.062 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Plastocyanin-like domain Complex1_LYR PF05347.10 KFX91374.1 - 0.0044 16.7 0.2 0.0075 16.0 0.2 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) SNF2_N PF00176.18 KFX91379.1 - 1e-75 254.3 0.0 1.5e-75 253.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFX91379.1 - 3.7e-06 26.7 0.0 8.8e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX91379.1 - 3.5e-05 23.6 0.0 7.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD_2 PF06733.10 KFX91379.1 - 0.014 14.8 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 HDA2-3 PF11496.3 KFX91379.1 - 0.056 12.2 0.0 1.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 NAD_binding_10 PF13460.1 KFX91380.1 - 7.2e-11 42.4 0.3 9.6e-11 42.0 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFX91380.1 - 9.6e-07 28.2 0.0 1.4e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family HIM1 PF08732.5 KFX91380.1 - 3.3e-05 22.5 0.0 0.0001 20.9 0.0 1.7 2 0 0 2 2 2 1 HIM1 NAD_binding_4 PF07993.7 KFX91380.1 - 0.0017 17.3 0.0 0.65 8.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 KFX91380.1 - 0.0022 16.7 0.0 0.0069 15.1 0.0 1.9 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KFX91380.1 - 0.0029 17.0 0.0 0.0052 16.2 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KFX91380.1 - 0.017 15.4 0.0 0.03 14.6 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KFX91380.1 - 0.024 13.5 0.0 0.45 9.3 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DUF1471 PF07338.8 KFX91380.1 - 0.095 12.3 0.1 0.28 10.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) FAD_binding_1 PF00667.15 KFX91381.1 - 3.7e-61 206.3 0.1 1.4e-60 204.4 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 KFX91381.1 - 1.7e-11 44.6 0.0 5.2e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 KFX91381.1 - 1.4e-09 38.1 0.0 3.1e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 KFX91381.1 - 0.0023 17.8 0.4 0.0086 16.0 0.1 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain Oxidored_FMN PF00724.15 KFX91395.1 - 5.7e-56 189.9 0.0 7.2e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FMN_dh PF01070.13 KFX91395.1 - 0.0018 17.1 1.4 0.15 10.8 0.4 2.4 2 0 0 2 2 2 2 FMN-dependent dehydrogenase Dus PF01207.12 KFX91395.1 - 0.13 11.0 0.4 1.6 7.5 0.0 2.4 2 1 0 2 2 2 0 Dihydrouridine synthase (Dus) Glyco_transf_90 PF05686.7 KFX91401.1 - 3.6e-06 25.9 0.0 0.00014 20.6 0.0 2.3 2 1 0 2 2 2 2 Glycosyl transferase family 90 ketoacyl-synt PF00109.21 KFX91402.1 - 6.9e-64 215.7 0.0 1.7e-63 214.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KFX91402.1 - 5.9e-31 107.9 3.9 2e-30 106.2 0.5 2.4 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KFX91402.1 - 4.9e-29 100.5 0.0 1.2e-28 99.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KFX91402.1 - 0.00077 18.5 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF95 PF01944.12 KFX91402.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF95 dsDNA_bind PF01984.15 KFX91415.1 - 0.12 12.4 0.6 0.22 11.5 0.4 1.4 1 0 0 1 1 1 0 Double-stranded DNA-binding domain Pik1 PF11522.3 KFX91416.1 - 1.7e-19 69.2 0.0 3.4e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 KFX91416.1 - 0.019 14.1 0.5 0.026 13.7 0.4 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Sec7_N PF12783.2 KFX91416.1 - 0.045 13.1 0.5 0.062 12.7 0.4 1.3 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Pkinase_Tyr PF07714.12 KFX91417.1 - 1.2e-19 70.4 0.0 8.7e-18 64.3 0.0 2.2 1 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 KFX91417.1 - 1.2e-19 70.5 0.0 5.8e-19 68.2 0.0 1.8 1 1 0 2 2 2 1 Protein kinase domain LRR_4 PF12799.2 KFX91417.1 - 4.9e-18 64.3 4.4 1.7e-05 24.2 0.0 5.0 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFX91417.1 - 3.4e-16 58.7 2.3 1.6e-09 37.3 0.2 3.4 2 1 1 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 KFX91417.1 - 1.4e-10 39.6 6.2 0.0017 18.1 0.3 6.6 7 0 0 7 7 7 2 Leucine Rich Repeat Kdo PF06293.9 KFX91417.1 - 2.6e-06 26.6 0.0 4.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_7 PF13504.1 KFX91417.1 - 3e-05 23.5 7.9 1.6 9.2 0.1 5.9 5 0 0 5 5 5 1 Leucine rich repeat Kinase-like PF14531.1 KFX91417.1 - 0.0026 16.7 0.0 0.004 16.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFX91417.1 - 0.0095 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFX91417.1 - 0.023 14.0 0.1 0.055 12.8 0.0 1.6 2 0 0 2 2 2 0 RIO1 family LRR_6 PF13516.1 KFX91417.1 - 0.27 11.4 5.1 33 4.9 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich repeat FNIP PF05725.7 KFX91417.1 - 6.2 6.8 5.9 1.6 8.7 0.2 2.9 3 0 0 3 3 2 0 FNIP Repeat DUF1279 PF06916.8 KFX91436.1 - 4.3e-27 94.2 0.0 1.1e-26 92.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Peptidase_A4 PF01828.12 KFX91437.1 - 0.064 12.3 2.1 0.11 11.5 1.5 1.3 1 0 0 1 1 1 0 Peptidase A4 family Chitin_bind_1 PF00187.14 KFX91439.1 - 0.00031 20.6 21.1 0.00031 20.6 14.6 2.3 2 0 0 2 2 2 1 Chitin recognition protein 6PGD PF00393.14 KFX91442.1 - 2.5e-64 217.3 0.0 3.5e-64 216.8 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KFX91442.1 - 6e-34 117.2 0.0 1.1e-33 116.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KFX91442.1 - 1.5e-05 24.7 0.0 2.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KFX91442.1 - 7.1e-05 22.5 0.0 0.00015 21.5 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 KFX91442.1 - 0.0011 18.3 0.1 0.0025 17.2 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 KFX91442.1 - 0.0027 17.1 0.0 0.0052 16.1 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 KFX91442.1 - 0.0032 16.6 0.0 0.0077 15.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dak1 PF02733.12 KFX91442.1 - 0.0052 15.4 0.0 0.013 14.0 0.0 1.6 2 0 0 2 2 2 1 Dak1 domain Pyr_redox PF00070.22 KFX91442.1 - 0.0082 16.5 0.1 0.038 14.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 KFX91442.1 - 0.011 16.1 0.0 0.028 14.8 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AP_endonuc_2 PF01261.19 KFX91443.1 - 1.9e-30 105.7 0.0 2.8e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel adh_short PF00106.20 KFX91443.1 - 6.8e-12 45.6 0.0 9.9e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX91443.1 - 3.5e-06 26.8 0.1 5.7e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFX91443.1 - 0.00011 22.0 0.1 0.00024 20.9 0.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 KFX91443.1 - 0.00051 19.7 0.1 0.0011 18.6 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KFX91443.1 - 0.021 14.2 0.0 0.049 13.0 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family WW PF00397.21 KFX91446.1 - 0.34 10.8 1.7 0.74 9.7 1.2 1.5 1 0 0 1 1 1 0 WW domain ACT_3 PF10000.4 KFX91448.1 - 2.5e-18 65.5 0.3 3.7e-18 65.0 0.2 1.2 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.1 KFX91448.1 - 3.6e-13 48.8 0.1 5.8e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 ACT domain Sugar_tr PF00083.19 KFX91449.1 - 3.5e-106 355.4 19.8 4.2e-106 355.2 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX91449.1 - 2.3e-24 85.8 27.4 2.8e-15 55.8 4.7 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 KFX91450.1 - 2.9e-31 109.0 2.4 1.3e-30 107.0 1.7 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family NUDIX PF00293.23 KFX91450.1 - 2e-18 66.3 0.2 6.7e-18 64.6 0.1 1.8 2 0 0 2 2 2 1 NUDIX domain Abhydrolase_1 PF00561.15 KFX91450.1 - 5.2e-15 55.6 0.1 1.1e-14 54.5 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX91450.1 - 1.4e-12 47.6 0.0 3.1e-09 36.7 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFX91450.1 - 4.9e-10 39.1 0.0 1.3e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S15 PF02129.13 KFX91450.1 - 0.032 13.6 0.0 4.9 6.4 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Methyltransf_2 PF00891.13 KFX91451.1 - 9.6e-35 119.9 0.0 1.5e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KFX91451.1 - 0.00015 22.2 0.0 0.00043 20.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX91451.1 - 0.0075 15.8 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 KFX91451.1 - 0.037 13.3 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Pyr_redox_3 PF13738.1 KFX91454.1 - 2e-25 90.0 0.0 1.8e-24 86.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFX91454.1 - 4e-17 62.1 0.2 3.9e-13 49.0 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KFX91454.1 - 4.8e-17 61.3 0.0 7e-16 57.5 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KFX91454.1 - 7e-13 48.9 0.0 8.5e-10 38.8 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX91454.1 - 1.5e-11 44.4 0.0 0.0002 21.7 0.0 3.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KFX91454.1 - 1.3e-10 41.5 0.3 3.6e-06 27.1 0.0 3.1 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 KFX91454.1 - 3.6e-08 33.7 0.6 0.0034 17.7 0.0 3.4 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent NAD_binding_8 PF13450.1 KFX91454.1 - 3.2e-07 30.2 0.0 3.4e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KFX91454.1 - 7.5e-07 29.0 1.3 0.083 12.6 0.0 3.7 3 1 1 4 4 4 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KFX91454.1 - 1.3e-06 27.6 0.7 0.019 13.8 0.0 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 KFX91454.1 - 1.5e-06 27.3 2.0 0.016 14.1 0.3 3.5 3 1 0 3 3 3 2 FAD dependent oxidoreductase TrkA_N PF02254.13 KFX91454.1 - 3.4e-06 27.0 0.2 0.18 11.8 0.0 3.3 3 0 0 3 3 3 2 TrkA-N domain FAD_binding_3 PF01494.14 KFX91454.1 - 4.7e-06 25.8 0.1 2.1e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.14 KFX91454.1 - 2.9e-05 23.2 0.0 0.01 14.9 0.0 2.6 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 KFX91454.1 - 0.00012 20.6 0.5 0.015 13.8 0.1 3.5 4 0 0 4 4 4 1 HI0933-like protein ThiF PF00899.16 KFX91454.1 - 0.00017 21.3 0.9 0.97 9.2 0.5 3.3 3 0 0 3 3 3 1 ThiF family AlaDh_PNT_C PF01262.16 KFX91454.1 - 0.00034 20.2 0.0 0.9 9.0 0.0 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 KFX91454.1 - 0.00071 19.7 0.0 0.1 12.8 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding 3HCDH_N PF02737.13 KFX91454.1 - 0.00089 18.9 0.0 0.46 10.1 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KFX91454.1 - 0.00093 18.1 3.4 0.0085 14.9 0.3 3.3 4 0 0 4 4 4 1 FAD binding domain Thi4 PF01946.12 KFX91454.1 - 0.0022 17.1 1.1 0.44 9.6 0.0 3.0 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.17 KFX91454.1 - 0.0037 16.1 0.4 2.7 6.7 0.0 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 KFX91454.1 - 0.0096 15.6 0.3 4.8 6.9 0.0 2.8 3 0 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ChlI PF13541.1 KFX91454.1 - 0.011 15.2 0.1 0.21 11.1 0.1 2.3 2 0 0 2 2 2 0 Subunit ChlI of Mg-chelatase IlvN PF07991.7 KFX91454.1 - 0.019 14.3 0.3 3.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Malic_M PF03949.10 KFX91454.1 - 0.07 12.6 0.1 7.6 5.9 0.0 2.4 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain CPSase_L_chain PF00289.17 KFX91454.1 - 0.11 12.6 0.0 5.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Zn_clus PF00172.13 KFX91455.1 - 5.7e-09 35.7 5.8 1.1e-08 34.7 4.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFX91455.1 - 0.00012 20.8 0.9 0.00036 19.2 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain WXG100 PF06013.7 KFX91455.1 - 0.16 11.9 0.7 0.47 10.5 0.5 1.8 1 1 0 1 1 1 0 Proteins of 100 residues with WXG RRN7 PF11781.3 KFX91455.1 - 7.6 6.1 9.1 20 4.7 6.3 1.7 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 Ank PF00023.25 KFX91471.1 - 4.8e-08 32.4 0.3 0.0015 18.2 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KFX91471.1 - 9.7e-08 32.2 0.0 1e-07 32.1 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFX91471.1 - 1.1e-07 31.8 0.4 0.00015 21.8 0.0 1.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX91471.1 - 0.00074 19.5 0.1 1.1 9.6 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KFX91471.1 - 0.013 16.0 0.1 0.024 15.1 0.1 1.5 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Methyltransf_31 PF13847.1 KFX91473.1 - 3.5e-21 75.3 0.0 5.2e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX91473.1 - 2.1e-16 60.4 0.1 3.4e-16 59.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX91473.1 - 6.4e-15 55.4 0.0 1e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX91473.1 - 1.2e-14 54.4 0.0 2.2e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX91473.1 - 1.1e-13 51.2 0.0 1.6e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX91473.1 - 1.3e-13 50.6 0.0 3.7e-13 49.1 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KFX91473.1 - 2.6e-12 47.0 0.1 7.9e-12 45.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX91473.1 - 5e-11 42.6 0.0 8.2e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX91473.1 - 1.6e-07 30.8 0.0 2.7e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KFX91473.1 - 4.3e-07 29.6 0.0 1.5e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 KFX91473.1 - 1.8e-05 23.9 0.0 2.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.13 KFX91473.1 - 0.00018 21.1 0.0 0.00037 20.1 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 TehB PF03848.9 KFX91473.1 - 0.00052 19.2 0.0 0.00091 18.4 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB FtsJ PF01728.14 KFX91473.1 - 0.00058 19.8 0.0 0.0014 18.6 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 KFX91473.1 - 0.00066 18.8 0.1 0.0012 18.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 KFX91473.1 - 0.0048 15.9 0.0 0.0085 15.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) DOT1 PF08123.8 KFX91473.1 - 0.005 16.1 0.0 0.012 14.9 0.0 1.6 1 1 0 1 1 1 1 Histone methylation protein DOT1 tRNA_U5-meth_tr PF05958.6 KFX91473.1 - 0.042 12.5 0.0 0.81 8.3 0.0 2.1 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase GCD14 PF08704.5 KFX91473.1 - 0.094 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit WD40 PF00400.27 KFX91483.1 - 1e-42 142.5 23.5 1.2e-12 47.1 0.2 5.3 5 0 0 5 5 5 5 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KFX91483.1 - 2.3e-06 27.4 13.4 0.0075 15.9 0.1 4.1 1 1 1 3 3 3 3 Transcription factor IIIC subunit delta N-term IKI3 PF04762.7 KFX91483.1 - 0.029 12.1 4.3 1.1 7.0 0.7 2.1 2 0 0 2 2 2 0 IKI3 family F-box-like PF12937.2 KFX91484.1 - 0.00013 21.5 0.3 0.00029 20.5 0.2 1.6 1 0 0 1 1 1 1 F-box-like DDE_Tnp_4 PF13359.1 KFX91484.1 - 0.055 13.0 0.3 0.34 10.4 0.1 2.0 2 0 0 2 2 2 0 DDE superfamily endonuclease Mating_C PF12737.2 KFX91484.1 - 0.3 9.9 12.6 0.44 9.3 8.7 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 GSDH PF07995.6 KFX91485.1 - 4e-05 22.8 0.0 8.8e-05 21.7 0.0 1.8 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase ABC_tran PF00005.22 KFX91488.1 - 1.1e-46 158.5 0.2 7.9e-22 78.0 0.0 3.1 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 KFX91488.1 - 1.7e-19 69.4 5.7 1.7e-19 69.4 3.9 3.4 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.1 KFX91488.1 - 7.8e-16 58.8 5.1 0.0005 20.1 0.0 4.9 5 1 1 6 6 5 3 AAA domain SMC_N PF02463.14 KFX91488.1 - 3.1e-11 42.9 3.8 0.00075 18.7 0.0 4.7 5 0 0 5 5 4 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KFX91488.1 - 2.3e-09 38.1 0.1 0.0029 18.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain MobB PF03205.9 KFX91488.1 - 7.6e-07 28.9 0.3 0.15 11.7 0.2 3.4 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KFX91488.1 - 8.6e-07 29.1 0.0 0.021 14.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KFX91488.1 - 1.1e-06 29.1 0.4 0.0056 17.1 0.0 2.9 3 0 0 3 3 2 2 Miro-like protein AAA_29 PF13555.1 KFX91488.1 - 3.2e-06 26.5 0.2 0.087 12.3 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KFX91488.1 - 1.2e-05 25.3 1.6 0.024 14.6 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 KFX91488.1 - 1.4e-05 24.3 0.0 0.064 12.4 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 KFX91488.1 - 1.7e-05 25.1 2.7 0.32 11.3 0.0 3.9 5 0 0 5 5 4 2 AAA domain AAA_33 PF13671.1 KFX91488.1 - 2.3e-05 24.3 0.0 0.18 11.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KFX91488.1 - 6e-05 22.6 0.5 0.93 8.8 0.1 3.8 3 1 0 3 3 3 2 AAA-like domain MMR_HSR1 PF01926.18 KFX91488.1 - 6.2e-05 22.9 0.0 0.14 12.0 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_15 PF13175.1 KFX91488.1 - 6.9e-05 22.0 11.4 0.36 9.8 0.1 5.1 4 2 0 5 5 5 2 AAA ATPase domain AAA PF00004.24 KFX91488.1 - 0.00015 22.0 3.3 0.93 9.7 0.1 4.3 5 1 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KFX91488.1 - 0.00022 21.6 16.7 0.03 14.6 0.0 4.6 5 0 0 5 5 5 2 AAA domain NACHT PF05729.7 KFX91488.1 - 0.00023 20.8 0.2 0.24 11.0 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_25 PF13481.1 KFX91488.1 - 0.00046 19.6 0.0 1.1 8.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KFX91488.1 - 0.00061 19.7 0.6 2 8.3 0.0 3.3 5 0 0 5 5 2 2 AAA domain RNA_helicase PF00910.17 KFX91488.1 - 0.0019 18.3 0.0 3.3 7.9 0.0 2.9 2 0 0 2 2 2 1 RNA helicase ArgK PF03308.11 KFX91488.1 - 0.0032 16.2 2.2 0.92 8.2 0.0 3.1 3 1 1 4 4 4 2 ArgK protein Zeta_toxin PF06414.7 KFX91488.1 - 0.0034 16.5 0.0 0.49 9.4 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin Dynamin_N PF00350.18 KFX91488.1 - 0.0038 17.0 5.1 2.3 8.0 0.0 4.0 4 0 0 4 4 4 1 Dynamin family SbcCD_C PF13558.1 KFX91488.1 - 0.0039 17.0 0.2 2.3 8.1 0.1 3.5 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.10 KFX91488.1 - 0.0046 16.6 0.1 1.2 8.8 0.0 2.9 3 0 0 3 3 2 1 NTPase AAA_28 PF13521.1 KFX91488.1 - 0.0052 16.7 6.9 0.25 11.3 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_24 PF13479.1 KFX91488.1 - 0.013 15.0 0.1 5 6.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 KFX91488.1 - 0.021 14.3 0.0 1.7 8.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.1 KFX91488.1 - 0.023 14.4 0.1 3.1 7.6 0.0 3.3 3 0 0 3 3 3 0 Part of AAA domain NB-ARC PF00931.17 KFX91488.1 - 0.03 13.2 0.1 5.6 5.7 0.0 2.9 3 0 0 3 3 3 0 NB-ARC domain AAA_5 PF07728.9 KFX91488.1 - 0.041 13.6 0.6 5.6 6.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) cobW PF02492.14 KFX91488.1 - 0.043 13.2 3.5 1.9 7.8 0.5 2.9 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KFX91488.1 - 0.072 12.5 0.1 14 5.2 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 KFX91488.1 - 0.31 10.8 10.4 1.3 8.7 0.0 4.5 6 0 0 6 6 6 0 Domain of unknown function DUF87 Tubulin PF00091.20 KFX91489.1 - 5.3e-70 235.6 0.0 9.2e-70 234.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFX91489.1 - 3.3e-49 166.1 0.1 5.3e-49 165.4 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KFX91489.1 - 1.9e-05 24.7 0.2 4.7e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KFX91489.1 - 0.0043 16.5 0.0 0.0071 15.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain GN3L_Grn1 PF08701.6 KFX91490.1 - 6e-23 80.5 12.7 6e-23 80.5 8.8 1.8 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 KFX91490.1 - 5.2e-22 77.9 0.2 2.1e-14 53.4 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFX91490.1 - 1.5e-06 28.1 7.4 0.0041 16.9 1.6 3.4 2 2 1 3 3 3 2 Dynamin family FeoB_N PF02421.13 KFX91490.1 - 2.5e-06 26.8 0.1 5e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KFX91490.1 - 6.9e-06 25.6 0.0 0.0074 15.7 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Miro PF08477.8 KFX91490.1 - 0.0013 19.1 0.6 2.1 8.8 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 KFX91490.1 - 0.0062 15.7 0.2 0.012 14.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ArgK PF03308.11 KFX91490.1 - 0.021 13.6 0.1 0.054 12.2 0.1 1.6 1 0 0 1 1 1 0 ArgK protein Arf PF00025.16 KFX91490.1 - 0.028 13.6 0.0 0.29 10.3 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.14 KFX91490.1 - 0.063 12.7 0.1 0.41 10.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 KFX91490.1 - 0.26 11.6 0.0 0.26 11.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KFX91490.1 - 0.31 11.0 3.9 1.5 8.7 0.1 2.8 2 1 0 2 2 2 0 AAA ATPase domain Daxx PF03344.10 KFX91490.1 - 0.83 8.0 16.5 1.3 7.4 11.4 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 KFX91490.1 - 3.1 5.6 22.6 4.7 5.0 15.7 1.2 1 0 0 1 1 1 0 Nop14-like family AAA_17 PF13207.1 KFX91490.1 - 8.4 7.2 9.4 0.54 11.0 0.1 2.8 2 1 0 2 2 2 0 AAA domain HAD_2 PF13419.1 KFX91491.1 - 2.2e-15 57.3 0.0 2.8e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFX91491.1 - 6.6e-11 41.7 0.1 1.2e-10 40.9 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KFX91491.1 - 6.6e-09 36.4 0.0 3.1e-07 31.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase SLD3 PF08639.5 KFX91492.1 - 1.3e-95 320.9 1.5 2.4e-95 320.0 1.0 1.4 1 0 0 1 1 1 1 DNA replication regulator SLD3 Cu-oxidase_3 PF07732.10 KFX91494.1 - 3.1e-48 162.3 0.6 7.8e-48 161.0 0.1 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 KFX91494.1 - 1e-38 132.7 0.5 3e-38 131.2 0.1 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFX91494.1 - 9e-05 22.0 0.6 0.0036 16.8 0.4 2.7 2 1 0 2 2 2 1 Multicopper oxidase FtsX PF02687.16 KFX91494.1 - 0.056 13.2 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 FtsX-like permease family Phosphoesterase PF04185.9 KFX91495.1 - 9.8e-34 117.1 4.8 1.9e-33 116.2 3.3 1.4 1 1 0 1 1 1 1 Phosphoesterase family FCH PF00611.18 KFX91502.1 - 4.1e-13 49.3 0.1 1.2e-12 47.8 0.1 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain RGCC PF15151.1 KFX91502.1 - 0.023 15.1 0.3 0.056 13.8 0.2 1.7 1 1 0 1 1 1 0 Response gene to complement 32 protein family Epimerase PF01370.16 KFX91512.1 - 2e-58 197.6 0.0 2.6e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFX91512.1 - 4.4e-23 81.6 0.0 4.4e-22 78.3 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KFX91512.1 - 1.9e-22 79.4 0.0 1.1e-21 76.9 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 KFX91512.1 - 1.1e-20 73.7 0.0 1.5e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 KFX91512.1 - 4.1e-20 71.6 0.0 9.9e-20 70.3 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFX91512.1 - 5.2e-09 36.3 0.0 9.4e-09 35.5 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KFX91512.1 - 0.00026 20.9 0.0 0.028 14.3 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Glyco_hydro_2_N PF02837.13 KFX91514.1 - 4.7e-09 36.0 0.9 1.3e-08 34.5 0.1 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KFX91514.1 - 2.9e-08 34.1 0.1 8.4e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 KFX91514.1 - 3.2e-05 22.9 0.0 6.9e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF402 PF04167.8 KFX91514.1 - 0.015 15.1 0.0 0.042 13.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF402) BChl_A PF02327.12 KFX91515.1 - 0.013 14.1 0.0 0.014 14.0 0.0 1.1 1 0 0 1 1 1 0 Bacteriochlorophyll A protein Lung_7-TM_R PF06814.8 KFX91539.1 - 3.2e-73 246.2 15.7 3.8e-73 246.0 10.9 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor PrgI PF12666.2 KFX91539.1 - 4.8 7.3 20.0 3.6 7.7 0.1 4.1 3 1 1 4 4 4 0 PrgI family protein DUF2392 PF10288.4 KFX91540.1 - 1.5e-28 99.2 0.0 2.6e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) RNA_pol_Rpc4 PF05132.9 KFX91541.1 - 3.9e-22 78.6 0.0 3.9e-22 78.6 0.0 2.3 3 1 0 3 3 3 1 RNA polymerase III RPC4 Thr_synth_N PF14821.1 KFX91541.1 - 0.17 11.9 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 Threonine synthase N terminus Cnd2 PF05786.9 KFX91544.1 - 1.7e-225 750.8 1.1 2.1e-225 750.5 0.7 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 Na_Ca_ex PF01699.19 KFX91545.1 - 8.2e-49 164.8 29.7 1.4e-26 92.7 4.0 2.7 2 0 0 2 2 2 2 Sodium/calcium exchanger protein PDR_CDR PF06422.7 KFX91545.1 - 0.012 15.2 0.1 0.91 9.2 0.0 2.9 2 0 0 2 2 2 0 CDR ABC transporter Vpu PF00558.14 KFX91545.1 - 4.6 6.8 4.8 9.2 5.9 0.0 3.1 3 0 0 3 3 3 0 Vpu protein MPC PF03650.8 KFX91546.1 - 2.1e-35 121.2 0.0 2.6e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) LSM PF01423.17 KFX91547.1 - 5.9e-17 60.9 0.0 7.8e-17 60.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Flag1_repress PF03614.8 KFX91547.1 - 0.09 12.3 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Ribosomal_L5_C PF00673.16 KFX91548.1 - 7.2e-22 76.9 0.0 1.2e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KFX91548.1 - 9.7e-21 73.3 0.0 2.3e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L5 PYC_OADA PF02436.13 KFX91550.1 - 2e-63 213.3 0.0 3.1e-63 212.7 0.0 1.3 1 0 0 1 1 1 1 Conserved carboxylase domain HMGL-like PF00682.14 KFX91550.1 - 2.6e-26 92.7 0.0 4.3e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.17 KFX91550.1 - 4.6e-17 61.4 5.4 9.3e-17 60.4 3.2 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_carb_C PF02785.14 KFX91550.1 - 1.4e-13 50.6 0.0 1.8e-12 47.2 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl_2 PF13533.1 KFX91550.1 - 2.9e-08 33.2 3.0 8.8e-08 31.6 0.2 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD PF00529.15 KFX91550.1 - 0.00067 19.0 0.7 0.0014 18.0 0.1 1.8 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_3 PF13437.1 KFX91550.1 - 0.0048 17.2 0.9 0.085 13.2 0.2 2.7 2 1 1 3 3 3 1 HlyD family secretion protein HlyD_2 PF12700.2 KFX91550.1 - 0.0083 15.3 0.9 0.024 13.8 0.3 1.8 1 1 1 2 2 2 1 HlyD family secretion protein DUF2118 PF09891.4 KFX91550.1 - 0.015 15.0 0.9 0.031 13.9 0.6 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) QRPTase_N PF02749.11 KFX91550.1 - 0.077 12.8 0.9 0.65 9.8 0.1 2.7 2 1 1 3 3 3 0 Quinolinate phosphoribosyl transferase, N-terminal domain NQRA PF05896.6 KFX91550.1 - 0.1 11.7 0.8 0.46 9.6 0.2 2.0 2 0 0 2 2 2 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) GCV_H PF01597.14 KFX91550.1 - 0.19 11.3 1.8 0.67 9.6 0.5 2.2 2 0 0 2 2 2 0 Glycine cleavage H-protein CPSase_L_D2 PF02786.12 KFX91551.1 - 1.3e-82 276.2 0.1 2.1e-82 275.5 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KFX91551.1 - 1.1e-35 122.0 0.0 2.4e-35 120.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KFX91551.1 - 5.4e-21 75.1 0.1 8.9e-21 74.4 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KFX91551.1 - 4.8e-17 61.6 0.0 3.5e-16 58.8 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KFX91551.1 - 4.1e-12 45.9 0.0 7.9e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 KFX91551.1 - 3e-09 36.6 0.0 7.9e-09 35.2 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 KFX91551.1 - 2.2e-08 33.6 0.1 3.7e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_carb_C PF02785.14 KFX91551.1 - 3.9e-07 30.0 0.0 7.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_3 PF02655.9 KFX91551.1 - 1.7e-06 28.0 0.3 8.1e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 KFX91551.1 - 0.0035 16.9 0.0 0.0082 15.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KH_4 PF13083.1 KFX91551.1 - 0.098 12.3 0.0 0.97 9.1 0.0 2.4 2 0 0 2 2 2 0 KH domain Clathrin PF00637.15 KFX91552.1 - 4.8e-209 684.3 41.4 2.7e-35 121.0 2.4 7.5 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 KFX91552.1 - 7.8e-33 112.1 0.4 4.5e-32 109.7 0.2 2.5 1 0 0 1 1 1 1 Clathrin-H-link Clathrin_propel PF01394.15 KFX91552.1 - 1.1e-30 103.7 0.4 3.1e-05 23.9 0.0 7.7 7 0 0 7 7 7 5 Clathrin propeller repeat TPR_7 PF13176.1 KFX91552.1 - 1.5e-05 24.4 4.9 16 5.5 0.0 7.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFX91552.1 - 0.00026 20.8 1.2 5.3 7.0 0.0 5.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Clathrin-link PF09268.5 KFX91552.1 - 0.00058 18.8 0.6 0.0016 17.4 0.1 2.1 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_1 PF00515.23 KFX91552.1 - 0.035 13.7 1.9 12 5.7 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Ank_3 PF13606.1 KFX91552.1 - 0.05 13.8 0.0 1 9.8 0.0 3.2 2 0 0 2 2 2 0 Ankyrin repeat TPR_2 PF07719.12 KFX91552.1 - 0.73 9.8 8.4 30 4.8 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFX91552.1 - 1.1 10.0 15.9 17 6.4 0.1 8.7 11 0 0 11 11 11 0 Tetratricopeptide repeat DUF1180 PF06679.7 KFX91553.1 - 0.8 9.5 3.0 0.98 9.2 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) MGC-24 PF05283.6 KFX91553.1 - 3.1 7.5 7.1 3.7 7.3 4.9 1.1 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) AICARFT_IMPCHas PF01808.13 KFX91554.1 - 2.4e-113 378.3 0.0 3.2e-113 377.9 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 KFX91554.1 - 7.5e-23 80.2 0.0 1.5e-22 79.2 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain WSC PF01822.14 KFX91560.1 - 1.4e-44 149.8 39.3 1.5e-15 56.9 5.9 4.0 3 0 0 3 3 3 3 WSC domain Glyco_hydro_18 PF00704.23 KFX91560.1 - 1.4e-17 64.1 0.7 1.6e-16 60.7 0.5 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KFX91560.1 - 3.1e-05 23.7 0.1 6.5e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 LysM domain DUF4531 PF15041.1 KFX91560.1 - 0.016 15.0 0.3 0.034 13.9 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4531) Sporozoite_P67 PF05642.6 KFX91560.1 - 2.4 5.9 6.0 1.4 6.6 2.2 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen UDPGP PF01704.13 KFX91562.1 - 3e-183 609.1 0.2 3.6e-183 608.8 0.1 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Neurensin PF14927.1 KFX91562.1 - 0.00043 19.6 0.9 0.0048 16.2 0.1 2.3 2 0 0 2 2 2 1 Neurensin DUF4301 PF14134.1 KFX91562.1 - 0.12 10.8 2.6 0.42 9.0 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4301) F-box-like PF12937.2 KFX91564.1 - 2.6e-05 23.8 0.5 5e-05 22.9 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX91564.1 - 0.00024 20.6 0.1 0.00054 19.5 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 KFX91564.1 - 0.0028 17.3 0.2 0.01 15.5 0.1 1.9 2 0 0 2 2 2 1 F-box-like domain Coatomer_WDAD PF04053.9 KFX91564.1 - 0.76 8.5 0.0 1.2 7.7 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region DUF908 PF06012.7 KFX91565.1 - 0.13 11.5 1.0 0.21 10.8 0.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) CBM_1 PF00734.13 KFX91566.1 - 5.7e-09 35.4 4.1 5.7e-09 35.4 2.8 3.0 4 0 0 4 4 4 2 Fungal cellulose binding domain MAR_sialic_bdg PF10564.4 KFX91566.1 - 3.5 7.4 6.4 1.2 8.9 0.2 2.4 2 1 0 2 2 2 0 Sialic-acid binding micronemal adhesive repeat EGF PF00008.22 KFX91566.1 - 8.9 6.3 9.7 6.3 6.8 0.9 2.5 2 1 0 2 2 2 0 EGF-like domain DUF2613 PF11021.3 KFX91567.1 - 0.015 14.9 3.2 0.062 13.0 2.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) UPF1_Zn_bind PF09416.5 KFX91568.1 - 1.6e-71 238.8 0.8 1.6e-71 238.8 0.5 1.7 2 0 0 2 2 1 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 KFX91568.1 - 9.2e-60 201.4 0.0 1.6e-59 200.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFX91568.1 - 8.5e-58 195.7 0.9 1.3e-57 195.0 0.6 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFX91568.1 - 1.3e-13 50.5 0.1 3.2e-13 49.2 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KFX91568.1 - 3.6e-12 46.2 0.2 5.9e-11 42.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 KFX91568.1 - 2.1e-08 34.2 0.0 3.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 KFX91568.1 - 8.8e-05 22.1 0.2 0.29 10.6 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 KFX91568.1 - 0.00072 18.6 0.4 0.0068 15.4 0.0 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 KFX91568.1 - 0.0019 17.8 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 KFX91568.1 - 0.0032 16.8 0.0 0.02 14.1 0.0 2.0 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 KFX91568.1 - 0.0037 16.2 0.0 0.36 9.7 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase DEAD PF00270.24 KFX91568.1 - 0.0072 15.8 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_S13_N PF08069.7 KFX91568.1 - 0.02 14.6 0.0 0.052 13.3 0.0 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_22 PF13401.1 KFX91568.1 - 0.047 13.8 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KFX91568.1 - 0.091 11.8 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.1 KFX91568.1 - 0.095 12.6 0.1 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.17 KFX91568.1 - 0.14 11.5 0.0 0.33 10.3 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain UvrD_C_2 PF13538.1 KFX91568.1 - 0.15 12.1 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain T2SE PF00437.15 KFX91568.1 - 0.22 10.3 0.0 0.37 9.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Brix PF04427.13 KFX91569.1 - 3.9e-46 157.1 0.8 6.7e-46 156.3 0.6 1.4 1 0 0 1 1 1 1 Brix domain SNARE PF05739.14 KFX91569.1 - 3.1e-15 55.5 0.9 3.1e-15 55.5 0.6 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KFX91569.1 - 5.5e-07 29.7 4.0 6.9e-07 29.3 0.7 2.4 2 0 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.1 KFX91569.1 - 0.0019 18.2 2.4 0.0019 18.2 1.7 2.5 2 0 0 2 2 2 1 Syntaxin-like protein Bac_export_3 PF01313.14 KFX91569.1 - 0.082 12.5 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Bacterial export proteins, family 3 BLOC1_2 PF10046.4 KFX91569.1 - 0.093 12.8 2.7 0.56 10.3 0.0 2.9 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMCO5 PF14992.1 KFX91569.1 - 0.47 9.5 6.7 0.86 8.6 0.6 2.3 2 0 0 2 2 2 0 TMCO5 family Tad PF13400.1 KFX91569.1 - 2.6 8.1 10.2 0.15 12.1 0.3 3.0 3 0 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like COPIIcoated_ERV PF07970.7 KFX91570.1 - 9.7e-37 126.7 0.3 1.5e-36 126.1 0.2 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KFX91570.1 - 4.3e-19 68.2 0.0 8.1e-19 67.3 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Peptidase_C97 PF05903.9 KFX91571.1 - 5.9e-07 29.3 0.1 1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF778 PF05608.7 KFX91571.1 - 0.079 12.9 0.5 0.18 11.7 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF778) LRAT PF04970.8 KFX91571.1 - 0.11 12.4 4.1 0.15 11.9 1.2 2.4 2 1 0 2 2 2 0 Lecithin retinol acyltransferase AhpC-TSA_2 PF13911.1 KFX91572.1 - 9.6e-20 70.6 0.0 6.8e-19 67.8 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KFX91572.1 - 0.00068 19.3 0.0 0.0014 18.3 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KFX91572.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 1 0 1 1 1 0 Redoxin DDHD PF02862.12 KFX91573.1 - 4.3 7.0 8.4 1.8 8.3 4.0 1.6 2 0 0 2 2 2 0 DDHD domain HET PF06985.6 KFX91575.1 - 1.5e-26 93.2 0.0 2.7e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WW PF00397.21 KFX91582.1 - 2.5e-07 30.3 0.3 5.3e-07 29.3 0.2 1.6 1 0 0 1 1 1 1 WW domain zf-BED PF02892.10 KFX91583.1 - 0.002 17.8 2.7 0.0042 16.8 1.8 1.5 1 0 0 1 1 1 1 BED zinc finger zf-C2H2 PF00096.21 KFX91583.1 - 0.022 15.0 3.5 0.059 13.7 2.4 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type Rib_recp_KP_reg PF05104.7 KFX91583.1 - 0.031 14.7 2.1 0.031 14.7 0.0 1.9 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region zf-C2H2_4 PF13894.1 KFX91583.1 - 0.035 14.4 2.5 0.083 13.2 1.7 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFX91583.1 - 0.067 13.5 2.7 5.3 7.5 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double domain Pex24p PF06398.6 KFX91601.1 - 3.5e-26 91.8 3.0 4.1e-26 91.6 2.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PARP PF00644.15 KFX91603.1 - 1.6e-12 47.2 0.0 1.6e-09 37.4 0.0 2.5 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain PTS_2-RNA PF01885.11 KFX91603.1 - 0.097 11.9 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family Rep_fac-A_C PF08646.5 KFX91604.1 - 0.12 12.0 0.5 0.23 11.1 0.3 1.4 1 0 0 1 1 1 0 Replication factor-A C terminal domain cobW PF02492.14 KFX91605.1 - 1.1e-37 129.2 0.0 1.6e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KFX91605.1 - 0.001 18.7 0.0 0.0026 17.4 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 KFX91605.1 - 0.019 14.4 0.3 0.28 10.7 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KFX91605.1 - 0.019 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 KFX91605.1 - 0.03 14.0 0.1 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain BESS PF02944.15 KFX91605.1 - 0.046 13.2 0.3 0.087 12.3 0.2 1.4 1 0 0 1 1 1 0 BESS motif Viral_helicase1 PF01443.13 KFX91605.1 - 0.066 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KFX91605.1 - 0.088 12.9 0.0 0.79 9.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KFX91605.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 2 0 0 2 2 2 0 AAA-like domain ETC_C1_NDUFA5 PF04716.9 KFX91605.1 - 0.2 11.1 0.4 0.63 9.6 0.0 1.9 2 0 0 2 2 2 0 ETC complex I subunit conserved region DUF3484 PF11983.3 KFX91606.1 - 2.3 9.1 8.4 8.6 7.2 0.2 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF3484) TPP_enzyme_N PF02776.13 KFX91609.1 - 4.3e-56 189.1 0.0 9.7e-56 187.9 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KFX91609.1 - 1.9e-36 124.8 0.3 9.1e-36 122.6 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 KFX91609.1 - 0.019 14.4 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg zf-C2H2 PF00096.21 KFX91610.1 - 0.00037 20.6 23.1 0.033 14.5 0.2 4.6 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 KFX91610.1 - 0.076 12.7 1.0 0.2 11.3 0.7 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.1 KFX91610.1 - 0.37 11.2 23.4 3 8.3 0.1 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger F-box-like PF12937.2 KFX91611.1 - 3.2e-05 23.5 0.2 0.0001 21.9 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX91611.1 - 0.00023 20.7 0.1 0.00047 19.7 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 KFX91611.1 - 0.23 11.1 2.8 0.35 10.6 1.5 1.6 1 1 0 1 1 1 0 F-box-like domain MFS_1 PF07690.11 KFX91615.1 - 4.7e-38 130.8 46.6 5.4e-38 130.6 28.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX91615.1 - 4.7e-06 25.4 17.4 2.4e-05 23.1 12.1 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter S-antigen PF05756.6 KFX91615.1 - 0.67 9.9 3.2 1.6 8.7 2.2 1.6 1 0 0 1 1 1 0 S-antigen protein Pectinesterase PF01095.14 KFX91617.1 - 7.7e-39 133.0 8.4 1.1e-38 132.5 5.8 1.1 1 0 0 1 1 1 1 Pectinesterase DUF2430 PF10353.4 KFX91617.1 - 0.062 13.4 0.0 5.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2430) Ribosomal_L28e PF01778.12 KFX91617.1 - 0.13 12.6 1.1 0.24 11.8 0.8 1.3 1 0 0 1 1 1 0 Ribosomal L28e protein family Pkinase PF00069.20 KFX91619.1 - 7e-63 212.2 0.0 9.1e-63 211.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX91619.1 - 8e-33 113.6 0.0 1.1e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX91619.1 - 0.00093 18.2 0.0 0.0017 17.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like UBA PF00627.26 KFX91627.1 - 4.3e-10 39.1 0.3 6.2e-10 38.6 0.2 1.3 1 0 0 1 1 1 1 UBA/TS-N domain NACHT PF05729.7 KFX91628.1 - 3.5e-09 36.5 0.0 8.5e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KFX91628.1 - 1.9e-06 28.0 0.0 8.4e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain TPR_12 PF13424.1 KFX91628.1 - 0.00042 20.2 0.9 0.0055 16.6 0.4 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat AAA_22 PF13401.1 KFX91628.1 - 0.0012 18.9 0.0 0.0042 17.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KFX91628.1 - 0.0066 16.6 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.9 KFX91628.1 - 0.016 14.9 0.1 1.1 9.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 KFX91628.1 - 0.027 14.6 0.0 0.13 12.4 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KFX91628.1 - 0.066 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 KFX91628.1 - 0.087 12.2 0.1 0.32 10.3 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 KFX91628.1 - 0.17 12.7 0.6 2.4 8.9 0.0 3.3 3 1 0 3 3 3 0 AAA domain GMC_oxred_N PF00732.14 KFX91629.1 - 1.9e-50 171.7 0.0 2.4e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFX91629.1 - 2.7e-34 118.5 0.0 4.1e-34 117.9 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KFX91629.1 - 6.2e-06 25.3 0.9 0.064 12.0 0.9 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KFX91629.1 - 0.00075 18.5 0.0 0.0016 17.3 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 KFX91629.1 - 0.0042 16.0 0.3 0.012 14.4 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KFX91629.1 - 0.014 14.5 0.1 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 KFX91629.1 - 0.031 14.2 0.4 0.085 12.8 0.3 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFX91629.1 - 0.045 13.6 0.0 0.15 11.9 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Catalase PF00199.14 KFX91631.1 - 1.3e-170 567.1 3.7 1.6e-170 566.9 2.5 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KFX91631.1 - 2.5e-14 52.8 0.0 7.4e-14 51.3 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive Pex14_N PF04695.8 KFX91632.1 - 0.058 13.4 0.5 0.066 13.2 0.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SBP_bac_5 PF00496.17 KFX91632.1 - 0.11 11.2 1.1 0.12 11.1 0.7 1.0 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle DUF2613 PF11021.3 KFX91632.1 - 0.12 12.1 0.3 0.24 11.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) CAP_N PF01213.14 KFX91632.1 - 0.21 10.8 1.1 0.22 10.8 0.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PAT1 PF09770.4 KFX91632.1 - 0.49 8.5 5.1 0.45 8.6 3.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4106 PF13388.1 KFX91632.1 - 5.9 5.7 7.7 6.1 5.6 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) EphA2_TM PF14575.1 KFX91633.1 - 0.0031 17.8 0.0 0.0055 17.0 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF1517 PF07466.6 KFX91633.1 - 0.06 12.3 1.3 0.094 11.6 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) SKG6 PF08693.5 KFX91633.1 - 0.063 12.5 0.2 0.14 11.4 0.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Glyco_hydro_11 PF00457.12 KFX91634.1 - 3.8e-54 182.8 13.4 4.4e-54 182.6 9.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Na_H_Exchanger PF00999.16 KFX91636.1 - 2.5e-68 230.3 37.1 3.2e-68 229.9 25.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PUCC PF03209.10 KFX91637.1 - 3.5e-06 25.9 1.2 6.7e-06 25.0 0.8 1.4 1 0 0 1 1 1 1 PUCC protein MFS_2 PF13347.1 KFX91637.1 - 0.00032 19.2 16.4 0.0034 15.8 11.4 2.3 1 1 0 1 1 1 1 MFS/sugar transport protein PKD PF00801.15 KFX91638.1 - 0.086 12.6 10.2 0.74 9.6 1.0 3.4 1 1 2 3 3 3 0 PKD domain DUF3664 PF12406.3 KFX91638.1 - 9.9 6.8 12.0 29 5.3 4.5 2.9 1 1 1 2 2 2 0 Surface protein Methyltransf_PK PF05891.7 KFX91639.1 - 9.1e-75 250.6 0.0 1e-74 250.5 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.2 KFX91639.1 - 0.1 13.1 0.1 0.22 12.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain UDPGT PF00201.13 KFX91639.1 - 0.19 10.2 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Aldedh PF00171.17 KFX91640.1 - 5.7e-181 601.8 0.7 6.5e-181 601.6 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Zip PF02535.17 KFX91641.1 - 8.5e-47 159.6 3.7 1.5e-46 158.8 2.6 1.3 1 1 0 1 1 1 1 ZIP Zinc transporter Glyco_hydro_47 PF01532.15 KFX91642.1 - 6.4e-133 443.7 0.0 7.8e-133 443.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.17 KFX91642.1 - 0.012 15.2 0.0 0.06 13.0 0.0 2.1 2 0 0 2 2 2 0 PA domain GST_N_3 PF13417.1 KFX91643.1 - 6.4e-11 42.3 0.0 1.4e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFX91643.1 - 3.6e-10 39.7 0.0 7.7e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KFX91643.1 - 4.6e-08 33.1 0.0 8.4e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFX91643.1 - 0.00011 21.9 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFX91643.1 - 0.0009 19.1 0.0 0.0019 18.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CRC_subunit PF08624.5 KFX91645.1 - 1.9e-58 196.3 0.1 2.6e-58 195.8 0.1 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit DUF2370 PF10176.4 KFX91650.1 - 9.6e-79 264.0 0.6 5.3e-78 261.5 0.4 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) FAD_binding_3 PF01494.14 KFX91652.1 - 4.1e-20 72.1 0.7 2.7e-10 39.8 0.1 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 KFX91652.1 - 2.9e-06 26.4 0.0 5.6e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX91652.1 - 2.5e-05 24.2 0.1 5.2e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFX91652.1 - 0.0016 18.7 0.1 0.13 12.7 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFX91652.1 - 0.0097 14.7 0.2 0.016 14.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.13 KFX91652.1 - 0.042 13.8 0.4 0.43 10.5 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.13 KFX91652.1 - 0.076 12.6 0.5 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_23 PF13489.1 KFX91653.1 - 7.5e-22 77.7 0.2 1.5e-21 76.7 0.1 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX91653.1 - 1.6e-09 38.1 0.0 3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX91653.1 - 3.5e-09 36.4 0.0 2e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX91653.1 - 1.8e-08 34.9 0.0 1.4e-07 32.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX91653.1 - 3.4e-06 27.4 0.0 2.3e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX91653.1 - 0.00026 21.2 0.0 0.00061 20.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KFX91653.1 - 0.0033 16.9 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 KFX91653.1 - 0.0066 16.4 0.0 0.018 15.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX91653.1 - 0.0079 15.5 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KFX91653.1 - 0.012 14.6 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 KFX91653.1 - 0.068 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KFX91653.1 - 0.12 11.4 0.0 1.1 8.3 0.0 2.2 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family DUF3815 PF12821.2 KFX91654.1 - 1.1e-24 86.8 17.4 2.2e-23 82.6 4.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) DUF1212 PF06738.7 KFX91654.1 - 6e-06 25.8 4.5 6e-06 25.8 3.1 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1212) MIG-14_Wnt-bd PF06664.7 KFX91654.1 - 0.039 12.7 1.5 0.045 12.5 0.6 1.4 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Fork_head PF00250.13 KFX91660.1 - 1.8e-34 117.6 0.2 3.6e-34 116.6 0.1 1.5 1 0 0 1 1 1 1 Fork head domain Cytomega_UL20A PF05984.7 KFX91660.1 - 0.11 12.7 0.3 0.93 9.7 0.1 2.5 1 1 1 2 2 2 0 Cytomegalovirus UL20A protein Peptidase_S9 PF00326.16 KFX91661.1 - 0.066 12.4 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Apolipoprotein PF01442.13 KFX91662.1 - 1.2e-05 24.9 8.2 0.0023 17.4 5.2 3.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain MHCassoc_trimer PF08831.5 KFX91662.1 - 0.0002 21.1 0.1 0.11 12.3 0.0 3.1 2 1 1 3 3 3 1 Class II MHC-associated invariant chain trimerisation domain DUF4108 PF13390.1 KFX91662.1 - 0.00034 20.3 0.4 0.0014 18.3 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4108) Globin PF00042.17 KFX91662.1 - 0.022 15.0 2.2 1.6 9.0 0.1 3.2 3 1 0 4 4 3 0 Globin DUF883 PF05957.8 KFX91662.1 - 0.035 14.4 9.4 1.7 9.0 0.1 4.6 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF883) Uteroglobin PF01099.12 KFX91662.1 - 0.068 12.9 2.1 0.21 11.4 0.0 2.8 3 0 0 3 3 3 0 Uteroglobin family Spore_III_AB PF09548.5 KFX91662.1 - 0.13 11.9 7.7 4 7.1 0.1 3.7 1 1 1 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) CorA PF01544.13 KFX91662.1 - 0.17 10.9 0.1 0.96 8.4 0.0 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Peptidase_M41 PF01434.13 KFX91662.1 - 0.33 10.4 5.8 0.25 10.7 0.3 2.8 1 1 1 3 3 3 0 Peptidase family M41 ApoL PF05461.6 KFX91662.1 - 0.36 10.0 7.3 0.82 8.8 0.1 3.3 2 1 1 3 3 3 0 Apolipoprotein L Syntaxin_2 PF14523.1 KFX91662.1 - 0.42 10.6 6.3 2.5 8.1 0.0 3.8 2 1 2 4 4 4 0 Syntaxin-like protein Flagellin_N PF00669.15 KFX91662.1 - 0.54 10.0 3.4 13 5.5 0.0 3.1 2 1 1 3 3 3 0 Bacterial flagellin N-terminal helical region Syntaxin-6_N PF09177.6 KFX91662.1 - 1.1 9.7 6.6 30 5.0 0.1 4.1 3 1 2 5 5 5 0 Syntaxin 6, N-terminal Ish1 PF10281.4 KFX91662.1 - 1.6 8.8 4.7 8.2 6.6 0.1 3.8 3 1 1 4 4 4 0 Putative stress-responsive nuclear envelope protein DUF1664 PF07889.7 KFX91662.1 - 8.3 6.2 10.4 2.1 8.1 0.0 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) BTB PF00651.26 KFX91668.1 - 8.9e-05 22.4 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Glyco_hydro_28 PF00295.12 KFX91672.1 - 3.3e-34 118.3 6.7 4.9e-34 117.7 4.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_28 PF00295.12 KFX91673.1 - 5.2e-39 134.1 16.1 6.5e-39 133.7 11.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 End_N_terminal PF12218.3 KFX91673.1 - 0.00027 20.3 0.4 0.00068 19.0 0.0 1.9 2 0 0 2 2 2 1 N terminal extension of bacteriophage endosialidase Pectinesterase PF01095.14 KFX91674.1 - 2.4e-49 167.5 8.4 3.1e-49 167.1 5.8 1.0 1 0 0 1 1 1 1 Pectinesterase Sugar_tr PF00083.19 KFX91675.1 - 3.4e-96 322.5 24.6 4.2e-96 322.2 17.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX91675.1 - 4.6e-30 104.5 29.8 8.1e-25 87.2 5.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX91675.1 - 0.0014 17.1 2.4 0.0014 17.1 1.7 3.4 2 2 1 3 3 3 2 MFS/sugar transport protein PUCC PF03209.10 KFX91675.1 - 0.58 8.8 14.1 0.03 13.0 4.6 2.4 3 0 0 3 3 3 0 PUCC protein Cpn60_TCP1 PF00118.19 KFX91676.1 - 5.8e-143 477.0 15.7 6.6e-143 476.8 10.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family tRNA-synt_2b PF00587.20 KFX91677.1 - 4.8e-21 75.0 0.1 5.9e-20 71.5 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFX91677.1 - 5.8e-19 67.8 0.0 1.3e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain ProRS-C_1 PF09180.6 KFX91677.1 - 3.9e-14 52.2 0.7 1.1e-13 50.9 0.5 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal DUF2048 PF09752.4 KFX91679.1 - 0.042 12.7 0.2 0.078 11.8 0.1 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Cep57_MT_bd PF06657.8 KFX91679.1 - 1.3 9.0 4.0 0.83 9.6 0.1 2.4 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 ALG3 PF05208.8 KFX91680.1 - 1.3e-141 472.1 16.0 1.5e-141 471.9 11.1 1.0 1 0 0 1 1 1 1 ALG3 protein eIF-1a PF01176.14 KFX91681.1 - 9.1e-16 57.0 0.0 2.1e-15 55.8 0.0 1.6 2 0 0 2 2 2 1 Translation initiation factor 1A / IF-1 DUF3306 PF11748.3 KFX91682.1 - 0.28 11.8 1.9 0.53 10.9 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) BCIP PF13862.1 KFX91683.1 - 3.9e-68 228.8 0.4 4.6e-68 228.5 0.3 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein CM_2 PF01817.16 KFX91684.1 - 1.1e-09 38.2 0.1 1.6e-06 28.1 0.0 3.0 2 1 0 2 2 2 2 Chorismate mutase type II LUC7 PF03194.10 KFX91688.1 - 6.2e-69 232.3 0.2 6.2e-69 232.3 0.1 2.5 3 0 0 3 3 3 1 LUC7 N_terminus YtzH PF14165.1 KFX91688.1 - 0.012 15.7 0.4 5.5 7.2 0.0 2.7 2 0 0 2 2 2 0 YtzH-like protein Abi_2 PF07751.6 KFX91688.1 - 0.033 14.3 0.3 0.033 14.3 0.2 2.3 2 0 0 2 2 2 0 Abi-like protein Gpi16 PF04113.9 KFX91689.1 - 2e-232 772.2 0.0 2.6e-232 771.8 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component DUF4066 PF13278.1 KFX91690.1 - 2.9e-21 75.4 0.0 4.3e-18 65.1 0.0 2.1 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 KFX91690.1 - 1e-07 31.5 0.0 2.5e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family DUF4123 PF13503.1 KFX91690.1 - 0.15 12.0 0.0 0.61 10.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4123) AAA PF00004.24 KFX91692.1 - 3.7e-17 62.7 0.0 7.1e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KFX91692.1 - 1.6e-13 50.6 0.0 4.7e-13 49.1 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KFX91692.1 - 3e-11 42.6 0.0 1.2e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 KFX91692.1 - 2.9e-07 29.7 0.3 3e-05 23.1 0.0 2.4 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KFX91692.1 - 3.6e-07 30.3 0.1 2.3e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KFX91692.1 - 6.8e-07 29.0 0.2 1.7e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFX91692.1 - 6.9e-07 29.4 0.1 7.1e-05 22.8 0.0 2.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 KFX91692.1 - 1.6e-06 27.7 0.0 4.2e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KFX91692.1 - 9e-06 25.4 0.5 3.4e-05 23.5 0.1 2.2 2 1 1 3 3 2 1 AAA domain (dynein-related subfamily) Rep_fac_C PF08542.6 KFX91692.1 - 1.1e-05 25.3 0.4 2.7e-05 24.0 0.0 1.9 2 0 0 2 2 1 1 Replication factor C C-terminal domain TIP49 PF06068.8 KFX91692.1 - 1.3e-05 24.1 0.0 0.065 11.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_11 PF13086.1 KFX91692.1 - 2.4e-05 24.0 0.1 0.00085 18.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 KFX91692.1 - 2.9e-05 23.1 0.0 5.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 KFX91692.1 - 3.8e-05 23.5 0.0 8e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 KFX91692.1 - 4e-05 23.1 0.1 9.1e-05 22.0 0.0 1.5 2 0 0 2 2 1 1 DNA polymerase III, delta subunit Sigma54_activat PF00158.21 KFX91692.1 - 0.00022 20.7 0.0 0.00043 19.8 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_24 PF13479.1 KFX91692.1 - 0.00022 20.8 0.0 0.00044 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KFX91692.1 - 0.00025 20.6 0.1 0.0012 18.4 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KFX91692.1 - 0.00098 18.4 0.0 0.39 9.9 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 KFX91692.1 - 0.001 18.2 0.1 0.013 14.7 0.0 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI DEAD PF00270.24 KFX91692.1 - 0.0017 17.8 0.0 0.028 13.8 0.0 2.4 2 1 1 3 3 2 1 DEAD/DEAH box helicase IstB_IS21 PF01695.12 KFX91692.1 - 0.0026 17.2 0.0 0.14 11.5 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.1 KFX91692.1 - 0.0028 17.0 0.1 0.014 14.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KFX91692.1 - 0.003 16.5 0.0 0.0047 15.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 KFX91692.1 - 0.0032 16.9 0.3 0.37 10.1 0.2 2.7 1 1 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 KFX91692.1 - 0.01 16.6 0.0 0.021 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KFX91692.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 KFX91692.1 - 0.027 13.2 0.0 2.1 7.0 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain RNA_helicase PF00910.17 KFX91692.1 - 0.027 14.6 0.0 0.093 12.9 0.0 2.0 1 1 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KFX91692.1 - 0.037 14.3 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KFX91692.1 - 0.042 13.3 0.1 0.25 10.8 0.0 2.2 2 1 1 3 3 3 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 KFX91692.1 - 0.057 13.1 0.0 0.2 11.3 0.0 1.9 1 1 0 1 1 1 0 Archaeal ATPase TK PF00265.13 KFX91692.1 - 0.065 12.7 0.1 0.18 11.3 0.0 1.7 2 0 0 2 2 2 0 Thymidine kinase TAFII28 PF04719.9 KFX91692.1 - 0.12 12.1 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 hTAFII28-like protein conserved region ResIII PF04851.10 KFX91692.1 - 0.13 12.0 0.0 0.59 9.9 0.0 1.8 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit XRCC1_N PF01834.11 KFX91693.1 - 0.0076 15.7 1.5 0.06 12.8 0.2 2.3 2 0 0 2 2 2 1 XRCC1 N terminal domain Fungal_trans PF04082.13 KFX91706.1 - 5.9e-11 41.7 0.1 1.5e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KFX91706.1 - 1.9e-09 37.2 7.9 5.7e-05 23.2 1.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX91706.1 - 6.6e-09 35.4 8.4 0.00019 21.5 0.9 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFX91706.1 - 1.9e-08 34.1 11.0 5.3e-06 26.4 2.3 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 KFX91706.1 - 8.5e-08 31.8 6.2 0.0042 16.9 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KFX91706.1 - 0.00012 22.1 4.6 0.011 15.8 0.2 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFX91706.1 - 0.00029 20.8 3.1 0.083 13.0 0.3 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding LIM PF00412.17 KFX91706.1 - 0.43 10.6 5.3 2.7 8.1 0.7 2.5 1 1 1 2 2 2 0 LIM domain RRN7 PF11781.3 KFX91706.1 - 1.9 8.0 6.1 2.1 7.9 0.1 3.0 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 ATP-grasp_4 PF13535.1 KFX91707.1 - 5.3e-12 45.8 0.0 3.4e-11 43.2 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain Methyltransf_25 PF13649.1 KFX91707.1 - 2.9e-09 37.2 0.0 1.8e-08 34.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Dala_Dala_lig_C PF07478.8 KFX91707.1 - 4.7e-09 35.9 0.0 2.8e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus Methyltransf_11 PF08241.7 KFX91707.1 - 1.8e-06 28.3 0.0 1.5e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX91707.1 - 2.2e-06 27.3 0.0 4.9e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ATP-grasp_3 PF02655.9 KFX91707.1 - 4.9e-06 26.4 0.0 2e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain Methyltransf_23 PF13489.1 KFX91707.1 - 3.8e-05 23.4 0.0 9.6e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX91707.1 - 7.7e-05 23.0 0.0 0.00022 21.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX91707.1 - 8.6e-05 23.0 0.0 0.00029 21.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX91707.1 - 0.0057 16.0 0.1 0.069 12.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KFX91707.1 - 0.024 14.6 0.0 0.089 12.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain THDPS_M PF14789.1 KFX91707.1 - 0.1 12.5 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase middle Cu_amine_oxid PF01179.15 KFX91708.1 - 4e-162 539.6 0.0 4.9e-162 539.3 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KFX91708.1 - 0.00018 21.5 0.0 0.00052 20.0 0.0 1.8 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 KFX91708.1 - 0.0026 17.7 0.0 0.006 16.6 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain T5orf172 PF10544.4 KFX91713.1 - 9.4e-13 48.4 1.2 2.5e-12 47.0 0.7 1.8 2 0 0 2 2 2 1 T5orf172 domain MUG113 PF13455.1 KFX91713.1 - 5.5e-06 26.7 8.3 0.0006 20.2 4.7 2.8 2 1 0 2 2 2 1 Meiotically up-regulated gene 113 HC2 PF07382.6 KFX91713.1 - 0.0011 18.8 10.9 0.0021 17.9 7.5 1.3 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 IER PF05760.7 KFX91713.1 - 0.097 12.5 8.2 0.0092 15.9 2.0 2.0 2 0 0 2 2 2 0 Immediate early response protein (IER) Na_H_Exchanger PF00999.16 KFX91723.1 - 7.2e-68 228.8 46.8 9.7e-68 228.4 32.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Usp PF00582.21 KFX91723.1 - 0.14 12.3 1.2 4.5 7.4 0.8 2.5 1 1 0 1 1 1 0 Universal stress protein family Mur_ligase_M PF08245.7 KFX91726.1 - 0.12 12.4 0.2 0.23 11.5 0.1 1.7 1 1 0 1 1 1 0 Mur ligase middle domain Mur_ligase_C PF02875.16 KFX91727.1 - 0.00013 21.9 0.0 0.0017 18.3 0.0 2.6 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.7 KFX91727.1 - 0.00051 20.1 0.3 0.033 14.2 0.2 2.9 1 1 0 1 1 1 1 Mur ligase middle domain Mitofilin PF09731.4 KFX91728.1 - 1.8e-147 492.4 9.8 2.8e-147 491.8 6.8 1.3 1 0 0 1 1 1 1 Mitochondrial inner membrane protein TFIIS_M PF07500.9 KFX91728.1 - 0.0027 17.7 3.6 0.0057 16.7 2.5 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain Exonuc_VII_L PF02601.10 KFX91728.1 - 1.9 7.5 10.0 3 6.9 6.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Ras PF00071.17 KFX91729.1 - 9e-59 197.4 0.3 1e-58 197.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX91729.1 - 1.9e-19 70.3 0.1 3.2e-19 69.5 0.0 1.4 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 KFX91729.1 - 1.8e-15 56.6 0.1 2.2e-15 56.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFX91729.1 - 1.9e-08 33.9 0.0 3.4e-08 33.1 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFX91729.1 - 7.9e-08 31.7 0.0 9.7e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFX91729.1 - 4.2e-06 26.7 0.0 6.4e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFX91729.1 - 0.007 16.5 0.0 0.64 10.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 KFX91729.1 - 0.02 14.0 0.2 0.085 12.0 0.0 2.0 2 1 0 3 3 3 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFX91729.1 - 0.045 13.7 0.3 0.12 12.3 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAT PF03417.11 KFX91729.1 - 0.061 12.7 0.1 0.091 12.1 0.1 1.2 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Amidase02_C PF12123.3 KFX91729.1 - 0.084 12.5 0.0 0.63 9.7 0.0 2.1 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase AAA_14 PF13173.1 KFX91729.1 - 0.11 12.3 0.1 0.21 11.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain Chromate_transp PF02417.10 KFX91743.1 - 8.9e-52 175.0 33.5 3e-27 95.2 8.7 2.4 3 0 0 3 3 3 2 Chromate transporter CcmH PF03918.9 KFX91743.1 - 0.15 11.0 0.1 0.83 8.6 0.0 2.3 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Ank_2 PF12796.2 KFX91759.1 - 1.1e-82 272.4 0.1 4.1e-17 62.3 0.0 8.3 3 2 5 8 8 8 7 Ankyrin repeats (3 copies) SMK-1 PF04802.10 KFX91759.1 - 1.7e-73 246.2 0.2 4e-73 245.0 0.2 1.7 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Ank_4 PF13637.1 KFX91759.1 - 8.5e-62 204.5 0.0 2.1e-08 34.4 0.0 10.3 4 2 7 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX91759.1 - 1e-60 200.3 0.0 3.3e-09 36.6 0.0 11.4 4 3 8 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.25 KFX91759.1 - 1.2e-56 185.8 0.0 9.4e-06 25.1 0.0 14.0 14 0 0 14 14 14 11 Ankyrin repeat Ank_3 PF13606.1 KFX91759.1 - 5e-46 150.0 0.0 0.00093 19.2 0.0 16.5 17 0 0 17 17 17 7 Ankyrin repeat NACHT PF05729.7 KFX91759.1 - 2.7e-06 27.1 1.4 6.6e-06 25.8 0.0 2.3 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.1 KFX91759.1 - 1e-05 25.6 0.0 3.5e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 KFX91759.1 - 0.01 14.8 1.2 0.3 10.0 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain Mg_chelatase PF01078.16 KFX91759.1 - 0.13 11.4 0.0 0.29 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TauD PF02668.11 KFX91760.1 - 1e-50 172.8 0.6 1.4e-50 172.3 0.4 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Y_phosphatase3 PF13350.1 KFX91760.1 - 2.9e-05 24.3 0.0 7.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KFX91760.1 - 0.0011 18.3 0.0 0.0042 16.4 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 KFX91760.1 - 0.0014 17.9 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family TPR_14 PF13428.1 KFX91760.1 - 0.035 14.7 0.0 0.16 12.6 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat DSPc PF00782.15 KFX91760.1 - 0.048 13.2 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Fungal_trans PF04082.13 KFX91761.1 - 5e-13 48.5 0.0 7.6e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX91761.1 - 3.6e-09 36.3 7.1 7.1e-09 35.4 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_1 PF00583.19 KFX91761.1 - 3.3e-05 23.8 0.0 6.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFX91761.1 - 7.6e-05 22.8 0.0 0.00017 21.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX91761.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain adh_short PF00106.20 KFX91762.1 - 1.5e-30 106.3 3.2 2.1e-30 105.8 2.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX91762.1 - 3.1e-17 62.8 0.3 3.7e-17 62.5 0.2 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFX91762.1 - 2.1e-15 57.1 0.2 2.8e-15 56.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFX91762.1 - 1.1e-07 31.5 0.6 1.9e-07 30.7 0.4 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFX91762.1 - 3.4e-05 22.9 0.0 5.9e-05 22.1 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KFX91762.1 - 0.00017 21.7 0.3 0.00027 21.0 0.2 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase PA PF02225.17 KFX91762.1 - 0.051 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 PA domain Eno-Rase_NADH_b PF12242.3 KFX91762.1 - 0.083 12.6 0.6 0.19 11.5 0.4 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MinC_C PF03775.11 KFX91762.1 - 0.085 12.4 0.2 0.17 11.4 0.2 1.5 1 0 0 1 1 1 0 Septum formation inhibitor MinC, C-terminal domain Pkinase PF00069.20 KFX91769.1 - 1.2e-37 129.4 0.0 1.6e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX91769.1 - 2e-17 63.1 0.0 3.3e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFX91769.1 - 0.0012 18.6 0.1 0.0031 17.2 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family muHD PF10291.4 KFX91770.1 - 1.6e-57 194.6 0.0 3.4e-57 193.5 0.0 1.5 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 KFX91770.1 - 1.3e-09 38.1 0.0 4.4e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Fib_alpha PF08702.5 KFX91770.1 - 0.031 14.4 2.9 0.074 13.1 2.0 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Muted PF14942.1 KFX91770.1 - 0.053 13.4 2.5 0.12 12.2 1.7 1.6 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Fis1_TPR_C PF14853.1 KFX91770.1 - 0.069 13.0 0.2 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Septin PF00735.13 KFX91776.1 - 8.3e-74 248.1 0.1 9.5e-74 247.9 0.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KFX91776.1 - 6.1e-08 32.6 0.0 8.2e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFX91776.1 - 2.1e-06 27.3 0.6 2.4e-05 23.8 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KFX91776.1 - 7.8e-06 25.1 0.0 1.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KFX91776.1 - 0.00067 19.5 0.5 0.27 11.0 0.0 2.2 1 1 1 2 2 2 2 Dynamin family AAA_24 PF13479.1 KFX91776.1 - 0.0011 18.6 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 KFX91776.1 - 0.0014 19.1 0.1 0.0021 18.5 0.1 1.6 1 1 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 KFX91776.1 - 0.0018 18.4 0.1 0.0038 17.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AIG1 PF04548.11 KFX91776.1 - 0.0018 17.4 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.8 KFX91776.1 - 0.0028 16.5 0.0 0.0036 16.1 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 KFX91776.1 - 0.0038 16.7 0.0 0.0071 15.8 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family Pox_A32 PF04665.7 KFX91776.1 - 0.0061 15.8 0.1 0.0094 15.2 0.0 1.2 1 0 0 1 1 1 1 Poxvirus A32 protein Ras PF00071.17 KFX91776.1 - 0.01 15.2 0.4 0.022 14.1 0.3 1.6 1 1 0 1 1 1 0 Ras family PduV-EutP PF10662.4 KFX91776.1 - 0.015 14.7 0.5 0.98 8.9 0.2 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation T2SE PF00437.15 KFX91776.1 - 0.015 14.1 0.1 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 KFX91776.1 - 0.021 14.4 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 KFX91776.1 - 0.025 14.3 0.0 0.033 13.9 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase Sigma54_activat PF00158.21 KFX91776.1 - 0.034 13.6 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain ATP_bind_1 PF03029.12 KFX91776.1 - 0.035 13.6 0.8 4.3 6.7 0.1 2.4 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.9 KFX91776.1 - 0.036 13.0 0.0 0.036 13.0 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_23 PF13476.1 KFX91776.1 - 0.045 14.0 0.0 0.061 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KFX91776.1 - 0.047 13.6 0.1 0.093 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 KFX91776.1 - 0.048 13.9 0.0 0.069 13.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.17 KFX91776.1 - 0.062 13.4 0.1 0.15 12.2 0.0 1.7 2 1 0 2 2 1 0 RNA helicase Gtr1_RagA PF04670.7 KFX91776.1 - 0.07 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_10 PF12846.2 KFX91776.1 - 0.071 12.5 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.9 KFX91776.1 - 0.071 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.13 KFX91776.1 - 0.12 11.7 0.2 0.37 10.0 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B WD40 PF00400.27 KFX91777.1 - 1.4e-53 176.9 29.3 1.1e-12 47.2 0.1 12.9 13 0 0 13 13 13 9 WD domain, G-beta repeat Utp12 PF04003.7 KFX91777.1 - 3.6e-28 97.6 0.0 5.7e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 KFX91777.1 - 1.4e-07 31.4 3.1 0.054 13.1 0.1 6.0 6 2 1 7 7 7 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFX91777.1 - 3e-05 22.3 2.9 0.3 9.1 0.2 3.7 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Nbas_N PF15492.1 KFX91777.1 - 0.012 14.6 0.1 1.9 7.5 0.0 2.7 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 KFX91777.1 - 0.026 12.8 0.0 1.2 7.3 0.0 3.1 3 1 0 3 3 3 0 Cytochrome D1 heme domain IBN_N PF03810.14 KFX91778.1 - 5e-12 45.5 0.2 3.7e-10 39.5 0.0 3.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.5 KFX91778.1 - 6e-05 21.7 0.2 0.00016 20.3 0.1 1.7 1 1 0 1 1 1 1 Cse1 HEAT_2 PF13646.1 KFX91778.1 - 0.00011 22.4 2.1 0.39 11.0 0.0 3.5 3 0 0 3 3 3 2 HEAT repeats Xpo1 PF08389.7 KFX91778.1 - 0.004 17.0 4.6 3.6 7.4 0.0 5.1 7 0 0 7 7 7 1 Exportin 1-like protein DUF2435 PF10363.4 KFX91778.1 - 0.01 15.7 0.5 0.051 13.4 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) Vac14_Fab1_bd PF12755.2 KFX91778.1 - 0.075 13.4 1.6 3.5 8.0 0.0 3.6 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region SprA-related PF12118.3 KFX91779.1 - 0.63 9.3 41.3 0.79 8.9 28.6 1.2 1 0 0 1 1 1 0 SprA-related family MIP-T3 PF10243.4 KFX91779.1 - 3.2 6.1 86.0 3.8 5.8 59.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 MFS_1 PF07690.11 KFX91781.1 - 2e-40 138.6 98.7 3.8e-37 127.8 42.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Epimerase PF01370.16 KFX91782.1 - 3.5e-15 56.0 0.0 5.5e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFX91782.1 - 1.7e-12 46.6 0.0 2.3e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFX91782.1 - 8.2e-11 42.2 0.4 1.9e-10 41.0 0.3 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KFX91782.1 - 5.4e-09 35.3 0.1 2.2e-08 33.3 0.1 1.8 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KFX91782.1 - 2.8e-07 30.6 0.5 5.6e-07 29.6 0.3 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KFX91782.1 - 4.4e-05 22.5 0.1 6.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KFX91782.1 - 0.0022 17.3 0.2 0.0034 16.6 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 KFX91782.1 - 0.0063 16.1 0.8 0.023 14.3 0.5 2.1 1 1 0 1 1 1 1 KR domain Glyco_hydro_18 PF00704.23 KFX91785.1 - 1.3e-60 205.7 6.9 5.9e-60 203.5 4.2 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KFX91785.1 - 5.8e-14 51.7 103.8 1.3e-05 25.0 9.1 4.9 4 0 0 4 4 4 4 Chitin recognition protein Transglut_core3 PF13471.1 KFX91786.1 - 0.1 12.4 0.2 0.18 11.5 0.2 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily Proteasome PF00227.21 KFX91787.1 - 6.6e-49 165.7 0.0 9.1e-49 165.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFX91787.1 - 5.4e-13 47.9 0.3 9e-13 47.2 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SCP2 PF02036.12 KFX91787.1 - 0.026 14.7 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 SCP-2 sterol transfer family DUF3650 PF12368.3 KFX91787.1 - 0.38 10.3 3.6 0.17 11.4 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3650) DUF2373 PF10180.4 KFX91788.1 - 2.3e-21 75.0 0.2 1.4e-20 72.5 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) Methyltransf_1N PF02870.10 KFX91788.1 - 0.064 13.8 0.2 0.93 10.1 0.1 2.7 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain DUF946 PF06101.6 KFX91789.1 - 1.8e-11 42.7 0.4 3e-11 42.0 0.3 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) DnaJ PF00226.26 KFX91790.1 - 9.9e-26 89.2 0.9 1.6e-25 88.6 0.7 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KFX91790.1 - 1.9e-16 59.8 14.1 3.4e-16 59.0 9.8 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 KFX91790.1 - 3.7e-13 49.1 0.0 4.5e-12 45.7 0.0 2.4 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 KFX91790.1 - 0.027 14.1 7.5 0.76 9.4 0.6 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family OB_NTP_bind PF07717.11 KFX91791.1 - 1.6e-25 89.1 0.0 3.9e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFX91791.1 - 2e-24 85.5 0.2 2e-24 85.5 0.1 2.7 2 0 0 2 2 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFX91791.1 - 4.1e-13 48.9 0.0 1.6e-12 47.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KFX91791.1 - 6.2e-06 26.3 0.0 1.9e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KFX91791.1 - 0.00019 20.9 0.0 0.00055 19.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 KFX91791.1 - 0.00054 18.9 0.0 0.0012 17.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein GYD PF08734.6 KFX91791.1 - 0.011 15.3 1.5 15 5.3 0.0 4.3 5 0 0 5 5 5 0 GYD domain AAA_14 PF13173.1 KFX91791.1 - 0.02 14.7 0.7 0.19 11.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KFX91791.1 - 0.046 14.0 1.6 0.12 12.6 0.0 2.5 2 1 0 2 2 2 0 ABC transporter SRP54 PF00448.17 KFX91791.1 - 0.05 13.0 0.1 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 KFX91791.1 - 0.057 13.1 0.1 0.2 11.4 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 KFX91791.1 - 0.2 11.9 0.0 0.2 11.9 0.0 3.7 2 1 0 2 2 1 0 AAA domain UTP15_C PF09384.5 KFX91792.1 - 2.2e-47 160.4 0.0 3.6e-47 159.7 0.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 KFX91792.1 - 1.1e-29 101.1 4.9 8.3e-10 38.1 0.0 6.1 6 1 0 6 6 6 3 WD domain, G-beta repeat Utp12 PF04003.7 KFX91792.1 - 0.049 13.5 0.2 1.1 9.1 0.1 2.4 1 1 0 1 1 1 0 Dip2/Utp12 Family RRM_1 PF00076.17 KFX91793.1 - 4e-36 122.4 0.2 4.9e-17 61.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX91793.1 - 2.4e-27 94.7 0.1 8.1e-13 48.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX91793.1 - 1.9e-13 50.0 0.1 5.4e-06 26.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFX91793.1 - 0.017 14.9 0.1 3.1 7.7 0.0 2.7 2 0 0 2 2 2 0 RNA binding motif RabGAP-TBC PF00566.13 KFX91794.1 - 4.9e-47 160.1 0.0 1e-46 159.1 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain MRC1 PF09444.5 KFX91795.1 - 4.3e-39 134.1 19.0 4.3e-39 134.1 13.2 7.3 4 2 3 7 7 7 2 MRC1-like domain Sulfate_transp PF00916.15 KFX91796.1 - 5.2e-06 25.6 15.5 1.7e-05 23.9 8.1 2.8 1 1 1 2 2 2 1 Sulfate transporter family Peptidase_M43 PF05572.8 KFX91797.1 - 8.7e-15 54.6 0.0 1.6e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 KFX91797.1 - 2e-05 25.0 0.1 5.2e-05 23.7 0.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFX91797.1 - 0.00061 19.7 1.0 0.0083 16.0 0.5 2.3 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KFX91797.1 - 0.0052 16.8 0.2 0.013 15.5 0.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFX91797.1 - 0.023 14.2 0.7 0.51 9.8 0.0 2.2 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Cutinase PF01083.17 KFX91805.1 - 0.00026 20.7 0.0 0.0006 19.5 0.0 1.6 1 0 0 1 1 1 1 Cutinase Abhydrolase_6 PF12697.2 KFX91805.1 - 0.0011 18.9 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KFX91805.1 - 0.0017 17.9 0.0 0.0039 16.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein FYVE PF01363.16 KFX91805.1 - 0.0058 16.4 4.6 0.0058 16.4 3.2 2.4 1 1 1 2 2 2 1 FYVE zinc finger Abhydrolase_5 PF12695.2 KFX91805.1 - 0.019 14.6 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 KFX91805.1 - 0.032 13.5 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2305 PF10230.4 KFX91805.1 - 0.085 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF726 PF05277.7 KFX91805.1 - 0.18 10.6 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) ZZ PF00569.12 KFX91805.1 - 0.57 9.7 30.8 2.4 7.7 6.8 3.2 2 1 0 2 2 2 0 Zinc finger, ZZ type DUF2628 PF10947.3 KFX91811.1 - 0.056 13.2 0.3 0.075 12.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) SMC_N PF02463.14 KFX91814.1 - 2.4e-67 226.3 11.1 1.1e-66 224.2 7.7 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KFX91814.1 - 1.8e-22 79.5 0.9 1.1e-21 76.9 0.2 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 KFX91814.1 - 1.8e-12 48.0 11.2 1.8e-12 48.0 7.8 6.5 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.1 KFX91814.1 - 1.8e-11 44.5 8.9 1.8e-05 24.8 0.0 3.7 4 1 0 4 4 4 2 AAA domain Reo_sigmaC PF04582.7 KFX91814.1 - 0.00052 19.2 33.8 0.13 11.4 1.6 6.1 3 2 2 6 6 6 4 Reovirus sigma C capsid protein AAA_29 PF13555.1 KFX91814.1 - 0.0008 18.8 0.0 0.0019 17.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KFX91814.1 - 0.13 12.5 0.0 0.13 12.5 0.0 6.2 4 2 0 4 4 4 0 ABC transporter Pox_A_type_inc PF04508.7 KFX91814.1 - 4.7 7.2 28.6 2.3 8.2 0.1 7.7 7 0 0 7 7 7 0 Viral A-type inclusion protein repeat 4HBT PF03061.17 KFX91815.1 - 2.8e-13 49.7 0.0 4.1e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 KFX91815.1 - 1.2e-06 28.5 0.1 1.9e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Thioesterase-like superfamily MOSC PF03473.12 KFX91816.1 - 2.6e-20 72.2 0.0 4.8e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 KFX91816.1 - 1.8e-12 47.0 0.0 3.3e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain FA_desaturase PF00487.19 KFX91817.1 - 5.8e-19 68.5 12.4 5.8e-19 68.5 8.6 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KFX91817.1 - 1.8e-16 59.7 0.1 5.7e-16 58.0 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Pex14_N PF04695.8 KFX91817.1 - 0.19 11.7 0.6 1.5 8.8 0.4 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Kei1 PF08552.6 KFX91820.1 - 1.2e-10 41.4 0.5 1.5e-10 41.0 0.3 1.2 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Nop53 PF07767.6 KFX91821.1 - 1e-102 344.0 25.3 1.4e-102 343.6 17.5 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Spore_YhcN_YlaJ PF09580.5 KFX91821.1 - 0.003 17.6 4.9 0.0068 16.5 3.4 1.5 1 0 0 1 1 1 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Ras PF00071.17 KFX91822.1 - 2.7e-59 199.1 0.3 3.6e-59 198.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX91822.1 - 1.5e-20 73.8 0.2 2.6e-20 73.0 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFX91822.1 - 8.6e-18 64.1 0.2 1.1e-17 63.8 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFX91822.1 - 2e-07 30.6 0.0 8.7e-07 28.5 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KFX91822.1 - 6.7e-06 25.4 0.3 8.6e-06 25.0 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFX91822.1 - 1.3e-05 25.1 0.0 2e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFX91822.1 - 4.5e-05 22.7 0.0 7.4e-05 22.0 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 KFX91822.1 - 0.036 13.8 0.1 3.3 7.5 0.0 2.5 2 1 0 2 2 2 0 Dynamin family AAA_22 PF13401.1 KFX91822.1 - 0.084 13.0 0.0 1.6 8.8 0.0 2.5 1 1 0 1 1 1 0 AAA domain Rubredoxin PF00301.15 KFX91824.1 - 0.032 14.0 0.2 0.075 12.9 0.1 1.6 1 0 0 1 1 1 0 Rubredoxin DUF3926 PF13080.1 KFX91824.1 - 1 8.9 11.6 12 5.5 0.2 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3926) GDI PF00996.13 KFX91825.1 - 1.1e-176 587.5 0.0 1.4e-176 587.1 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor MRP-L47 PF06984.8 KFX91825.1 - 1.1e-20 73.3 0.3 2.1e-20 72.4 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) NAD_binding_8 PF13450.1 KFX91825.1 - 0.092 12.7 0.1 0.28 11.2 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain zf-H2C2_2 PF13465.1 KFX91826.1 - 6.3e-06 26.2 1.2 6.3e-06 26.2 0.8 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFX91826.1 - 4.2e-05 23.5 13.7 0.0034 17.6 3.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 KFX91826.1 - 0.0014 18.7 3.2 0.0026 17.8 2.2 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding DUF3464 PF11947.3 KFX91826.1 - 0.13 11.7 4.8 0.93 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) zf-C2H2_jaz PF12171.3 KFX91826.1 - 0.35 11.0 3.3 9.6 6.4 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KFX91826.1 - 0.44 10.3 6.4 0.63 9.8 0.4 2.5 2 0 0 2 2 2 0 BED zinc finger DivIC PF04977.10 KFX91826.1 - 6.7 6.2 10.3 12 5.5 7.1 1.3 1 0 0 1 1 1 0 Septum formation initiator zf-C2H2 PF00096.21 KFX91826.1 - 8.2 6.9 24.2 0.19 12.1 4.1 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type V-ATPase_H_N PF03224.9 KFX91828.1 - 7.7e-54 182.9 0.0 1e-53 182.4 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 KFX91828.1 - 7.9e-40 135.4 0.0 1.5e-39 134.6 0.0 1.4 1 0 0 1 1 1 1 V-ATPase subunit H HEAT_2 PF13646.1 KFX91828.1 - 0.26 11.6 2.4 13 6.1 0.0 3.9 3 2 0 3 3 3 0 HEAT repeats HEAT_EZ PF13513.1 KFX91828.1 - 1.4 9.4 5.8 31 5.2 0.0 4.2 5 1 1 6 6 6 0 HEAT-like repeat Nol1_Nop2_Fmu PF01189.12 KFX91845.1 - 1.1e-14 54.5 0.1 4.9e-09 35.9 0.0 3.5 2 1 0 2 2 2 2 NOL1/NOP2/sun family Choline_transpo PF04515.7 KFX91849.1 - 0.0051 15.6 3.7 0.0051 15.6 2.6 1.3 1 1 0 1 1 1 1 Plasma-membrane choline transporter AP_endonuc_2 PF01261.19 KFX91850.1 - 5.4e-29 101.0 0.0 7.8e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DDE_1 PF03184.14 KFX91857.1 - 3.6e-16 58.9 0.0 5.7e-16 58.3 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease Trypan_PARP PF05887.6 KFX91857.1 - 0.96 9.2 10.7 0.15 11.8 1.7 2.3 2 1 1 3 3 3 0 Procyclic acidic repetitive protein (PARP) Ank_2 PF12796.2 KFX91858.1 - 4.4e-30 103.8 0.8 1.7e-10 41.0 0.0 3.1 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFX91858.1 - 1.2e-26 92.6 1.9 5.4e-09 36.3 0.1 3.5 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KFX91858.1 - 8.7e-25 85.2 3.7 4.8e-06 26.0 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 KFX91858.1 - 3.9e-24 84.1 2.7 2.1e-06 27.7 0.0 4.9 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX91858.1 - 4.4e-16 57.3 1.7 0.017 15.3 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat F-box-like PF12937.2 KFX91858.1 - 1.8e-06 27.5 0.1 4.2e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like p450 PF00067.17 KFX91860.1 - 8e-07 27.9 0.0 1.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 BAR PF03114.13 KFX91869.1 - 1.7e-48 165.1 5.8 2.2e-48 164.7 4.0 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 KFX91869.1 - 0.00011 21.1 2.7 0.00015 20.8 1.9 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking GBP_C PF02841.9 KFX91869.1 - 5.6 6.0 13.0 0.33 10.0 4.9 1.7 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain NAD_binding_10 PF13460.1 KFX91874.1 - 7.9e-07 29.2 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KFX91874.1 - 0.0022 18.2 0.0 0.0045 17.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KFX91874.1 - 0.011 14.6 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KFX91874.1 - 0.025 13.5 0.0 0.22 10.4 0.0 2.2 1 1 0 2 2 2 0 Male sterility protein KR PF08659.5 KFX91874.1 - 0.041 13.5 0.0 0.66 9.6 0.0 2.2 2 0 0 2 2 2 0 KR domain DapB_N PF01113.15 KFX91874.1 - 0.068 13.0 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sugar_tr PF00083.19 KFX91875.1 - 3.7e-78 263.0 18.3 4.4e-78 262.8 12.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX91875.1 - 5.7e-22 77.8 28.1 1.2e-21 76.8 18.0 2.3 1 1 2 3 3 3 3 Major Facilitator Superfamily zf-C2H2_4 PF13894.1 KFX91876.1 - 0.2 12.0 18.5 0.33 11.3 1.0 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFX91876.1 - 3.2 8.2 13.9 0.06 13.7 2.2 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF4246 PF14033.1 KFX91877.1 - 4.9e-128 427.8 0.1 5.8e-110 368.2 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF4246) DUF4637 PF15470.1 KFX91878.1 - 0.087 12.4 0.2 0.098 12.2 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Op_neuropeptide PF08035.6 KFX91880.1 - 0.0061 16.1 0.1 0.034 13.7 0.0 2.2 2 0 0 2 2 2 1 Opioids neuropeptide DEAD PF00270.24 KFX91885.1 - 3.2e-35 121.1 0.0 7.2e-35 119.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KFX91885.1 - 1.7e-18 65.8 0.0 3.5e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KFX91885.1 - 1.1e-17 63.5 0.0 2.7e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX91885.1 - 0.0081 16.0 1.2 0.039 13.7 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit CTP_transf_1 PF01148.15 KFX91886.1 - 3e-15 56.5 8.4 1.7e-13 50.8 5.8 2.3 1 1 0 1 1 1 1 Cytidylyltransferase family KxDL PF10241.4 KFX91887.1 - 4e-23 81.1 1.8 5.5e-23 80.6 1.3 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF883 PF05957.8 KFX91887.1 - 0.027 14.8 5.8 0.15 12.4 1.7 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Peripla_BP_2 PF01497.13 KFX91887.1 - 0.056 12.5 0.1 0.071 12.2 0.1 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Mating_C PF12737.2 KFX91887.1 - 3.4 6.4 15.8 1.7 7.4 1.2 2.7 2 1 1 3 3 3 0 C-terminal domain of homeodomain 1 PBP1_TM PF14812.1 KFX91889.1 - 0.82 10.0 7.0 0.18 12.1 2.2 1.8 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TT_ORF2 PF02957.10 KFX91889.1 - 1.7 9.3 6.3 0.21 12.3 0.5 2.1 3 0 0 3 3 3 0 TT viral ORF2 Ribosomal_L2_C PF03947.13 KFX91900.1 - 3.1e-37 127.2 3.6 5e-37 126.5 2.5 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KFX91900.1 - 3.4e-14 52.5 0.1 6.6e-14 51.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PfkB PF00294.19 KFX91901.1 - 9.8e-67 225.1 0.1 1.1e-66 224.9 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KFX91901.1 - 0.038 13.1 0.0 0.098 11.8 0.0 1.7 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.4 KFX91902.1 - 3.8e-52 177.2 0.0 8.3e-52 176.1 0.0 1.6 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 KFX91902.1 - 1.1e-18 67.5 0.8 3e-18 66.0 0.6 1.8 1 0 0 1 1 1 1 Telomerase activating protein Est1 TPR_12 PF13424.1 KFX91902.1 - 0.00028 20.7 1.6 0.00073 19.4 1.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFX91902.1 - 0.00046 19.7 0.7 0.0014 18.1 0.5 1.9 1 0 0 1 1 1 1 TPR repeat zf-C2H2 PF00096.21 KFX91903.1 - 3.8 8.0 14.5 0.65 10.4 0.9 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type TB2_DP1_HVA22 PF03134.14 KFX91904.1 - 9.3e-32 108.6 5.2 1.4e-31 108.0 3.6 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Kei1 PF08552.6 KFX91904.1 - 0.16 11.6 5.4 2.8 7.5 1.8 2.2 2 1 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Bestrophin PF01062.16 KFX91904.1 - 1.4 7.7 7.2 4.1 6.2 5.0 1.7 1 1 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel DUF2207 PF09972.4 KFX91904.1 - 3 6.3 9.8 5.4 5.4 6.8 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) RFX_DNA_binding PF02257.10 KFX91905.1 - 4.9e-30 103.5 0.1 1.5e-29 101.9 0.1 1.9 1 0 0 1 1 1 1 RFX DNA-binding domain Mid1 PF12929.2 KFX91906.1 - 0.011 14.4 0.0 0.014 14.1 0.0 1.1 1 0 0 1 1 1 0 Stretch-activated Ca2+-permeable channel component Mid1 PF12929.2 KFX91907.1 - 6.8e-126 420.4 1.0 7.6e-126 420.2 0.7 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 KFX91907.1 - 0.0021 18.3 1.6 0.088 13.1 0.2 2.3 2 0 0 2 2 2 2 Fz domain Fungal_trans PF04082.13 KFX91909.1 - 8.4e-07 28.1 0.1 1.4e-06 27.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_2_N PF02837.13 KFX91910.1 - 8.5e-26 90.4 0.0 3.1e-25 88.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KFX91910.1 - 3.9e-13 48.9 0.0 1.7e-12 46.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KFX91910.1 - 9.8e-11 42.0 0.1 6.2e-10 39.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 KFX91910.1 - 0.00035 20.8 0.3 0.00093 19.4 0.1 1.9 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain DUF4066 PF13278.1 KFX91911.1 - 4e-19 68.4 0.0 6.1e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KFX91911.1 - 0.025 14.0 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family Mre11_DNA_bind PF04152.9 KFX91912.1 - 4.1e-54 183.0 0.2 6.9e-54 182.3 0.1 1.4 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 KFX91912.1 - 1e-24 87.0 2.1 1.4e-24 86.6 1.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFX91912.1 - 2.4e-06 27.4 0.4 6.8e-06 25.9 0.2 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF605 PF04652.11 KFX91912.1 - 0.49 9.7 13.4 0.74 9.1 9.3 1.2 1 0 0 1 1 1 0 Vta1 like Ribosomal_S19 PF00203.16 KFX91913.1 - 7.1e-23 80.0 0.2 9.7e-23 79.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 SnoaL_2 PF12680.2 KFX91914.1 - 0.035 14.5 0.0 0.081 13.3 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain Pkinase PF00069.20 KFX91918.1 - 4e-47 160.5 0.0 5.2e-47 160.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX91918.1 - 3.5e-19 68.8 0.0 5.4e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX91918.1 - 0.0023 16.9 0.0 0.013 14.4 0.0 2.2 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 KFX91918.1 - 0.021 14.5 0.1 5.4 6.6 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.17 KFX91918.1 - 0.085 12.1 0.2 0.25 10.6 0.0 1.7 1 1 1 2 2 2 0 RIO1 family Cir_N PF10197.4 KFX91919.1 - 0.0043 17.0 0.9 0.0043 17.0 0.6 3.5 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Rhomboid PF01694.17 KFX91921.1 - 6.5e-35 120.3 11.8 6.5e-35 120.3 8.2 1.9 2 0 0 2 2 2 1 Rhomboid family BSP_II PF05432.6 KFX91921.1 - 0.021 14.0 0.1 0.032 13.5 0.1 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DNA_pol_B PF00136.16 KFX91922.1 - 3.4e-146 487.6 3.1 5e-146 487.1 2.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KFX91922.1 - 1.9e-80 270.1 0.3 4.2e-80 269.0 0.1 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KFX91922.1 - 1.4e-22 79.4 6.4 4.3e-22 77.9 4.4 1.9 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 KFX91922.1 - 0.00019 21.2 0.3 0.0012 18.6 0.2 2.5 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 KFX91922.1 - 0.0003 20.3 0.1 0.00059 19.4 0.1 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.17 KFX91922.1 - 0.095 12.4 10.6 0.13 11.9 0.8 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Acyl-CoA_dh_1 PF00441.19 KFX91924.1 - 3.9e-35 121.1 0.1 7.3e-35 120.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFX91924.1 - 3.8e-16 58.3 0.2 1.2e-15 56.7 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFX91924.1 - 7.7e-13 48.8 0.3 3.5e-12 46.7 0.0 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFX91924.1 - 1.9e-10 41.3 0.0 1.4e-09 38.5 0.0 2.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain CFEM PF05730.6 KFX91924.1 - 5.5e-08 32.5 6.5 1.1e-07 31.5 4.5 1.6 1 0 0 1 1 1 1 CFEM domain HpaB_N PF11794.3 KFX91924.1 - 0.0028 17.0 0.7 0.0059 16.0 0.0 1.8 2 0 0 2 2 2 1 4-hydroxyphenylacetate 3-hydroxylase N terminal adh_short_C2 PF13561.1 KFX91925.1 - 0.0023 17.7 0.0 0.0034 17.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FleQ PF06490.6 KFX91925.1 - 0.12 12.5 0.0 44 4.2 0.0 3.0 2 1 1 3 3 3 0 Flagellar regulatory protein FleQ G-patch_2 PF12656.2 KFX91929.1 - 1e-19 70.1 5.5 2e-19 69.1 0.1 3.1 3 0 0 3 3 3 2 DExH-box splicing factor binding site UbiA PF01040.13 KFX91930.1 - 0.13 11.4 1.9 0.16 11.1 0.4 1.7 1 1 1 2 2 2 0 UbiA prenyltransferase family DUF1049 PF06305.6 KFX91930.1 - 0.67 9.4 2.7 1.6 8.2 1.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1049) Fcf1 PF04900.7 KFX91931.1 - 2.7e-40 136.5 0.2 4.8e-40 135.7 0.1 1.4 1 0 0 1 1 1 1 Fcf1 ATP-synt_S1 PF05827.7 KFX91932.1 - 3.7e-26 92.0 0.0 8.3e-26 90.9 0.0 1.5 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) DUF3176 PF11374.3 KFX91932.1 - 0.65 9.8 3.7 2.1 8.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3176) Nop25 PF09805.4 KFX91933.1 - 3.2e-31 108.2 12.3 3.2e-31 108.2 8.5 2.5 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) RNA_pol_Rpc82 PF05645.8 KFX91933.1 - 0.0035 16.9 0.3 0.0035 16.9 0.2 2.1 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 Dala_Dala_lig_N PF01820.16 KFX91933.1 - 2.2 8.5 7.2 14 6.0 1.5 2.6 2 1 0 2 2 2 0 D-ala D-ala ligase N-terminus Tropomyosin_1 PF12718.2 KFX91934.1 - 8.6e-49 165.0 35.3 9.9e-49 164.8 24.4 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 KFX91934.1 - 3.8e-10 39.2 31.2 9.2e-07 28.1 12.7 2.3 1 1 1 2 2 2 2 Tropomyosin GAS PF13851.1 KFX91934.1 - 0.00025 20.3 29.3 0.00039 19.6 20.3 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Cast PF10174.4 KFX91934.1 - 0.00031 18.9 27.3 0.00034 18.8 18.9 1.0 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone ERM PF00769.14 KFX91934.1 - 0.00038 20.0 33.2 0.0021 17.6 8.0 2.1 1 1 1 2 2 2 2 Ezrin/radixin/moesin family Vps5 PF09325.5 KFX91934.1 - 0.0063 15.8 6.3 0.0063 15.8 4.4 2.8 1 1 1 3 3 3 1 Vps5 C terminal like EzrA PF06160.7 KFX91934.1 - 0.02 13.0 23.7 0.072 11.2 1.8 2.0 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA TMF_TATA_bd PF12325.3 KFX91934.1 - 0.021 14.5 26.3 0.099 12.3 13.3 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 KFX91934.1 - 0.023 14.3 29.3 3.2 7.3 20.3 2.5 1 1 0 1 1 1 0 IncA protein CENP-F_leu_zip PF10473.4 KFX91934.1 - 0.03 14.2 32.0 0.033 14.0 1.4 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 KFX91934.1 - 0.031 13.3 32.7 0.045 12.7 16.7 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF3584 PF12128.3 KFX91934.1 - 0.039 11.2 24.1 0.048 11.0 16.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Myosin_tail_1 PF01576.14 KFX91934.1 - 0.04 11.6 33.8 0.12 10.1 23.4 1.6 1 1 0 1 1 1 0 Myosin tail KLRAQ PF10205.4 KFX91934.1 - 0.043 13.8 19.8 0.043 13.8 7.0 2.6 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein Rab5-bind PF09311.6 KFX91934.1 - 0.046 13.5 25.1 0.061 13.2 17.4 1.2 1 0 0 1 1 1 0 Rabaptin-like protein BLOC1_2 PF10046.4 KFX91934.1 - 0.047 13.8 21.5 0.81 9.8 6.8 3.4 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.4 KFX91934.1 - 0.048 12.5 25.4 0.029 13.3 12.2 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Filament PF00038.16 KFX91934.1 - 0.065 12.6 26.8 0.12 11.8 18.6 1.3 1 0 0 1 1 1 0 Intermediate filament protein bZIP_1 PF00170.16 KFX91934.1 - 0.069 13.1 31.5 1.5 8.8 0.5 4.8 1 1 2 4 4 4 0 bZIP transcription factor Seryl_tRNA_N PF02403.17 KFX91934.1 - 0.075 13.0 27.6 2.2 8.3 3.8 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.6 KFX91934.1 - 0.11 12.3 29.2 1.3 8.7 7.1 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF869 PF05911.6 KFX91934.1 - 0.14 10.3 25.1 0.42 8.7 17.4 1.6 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) ADIP PF11559.3 KFX91934.1 - 0.15 11.9 31.9 0.93 9.3 9.6 2.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.1 KFX91934.1 - 0.17 10.2 25.1 0.43 8.9 17.4 1.6 1 1 0 1 1 1 0 AAA domain NABP PF07990.7 KFX91934.1 - 0.18 11.0 5.8 0.19 10.9 4.0 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Laminin_II PF06009.7 KFX91934.1 - 0.25 11.1 18.8 0.21 11.3 4.0 2.7 1 1 1 2 2 2 0 Laminin Domain II WEMBL PF05701.6 KFX91934.1 - 0.28 9.5 32.7 0.18 10.2 18.7 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Jnk-SapK_ap_N PF09744.4 KFX91934.1 - 0.33 10.9 28.8 0.064 13.2 13.3 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Reo_sigmaC PF04582.7 KFX91934.1 - 0.37 9.9 2.8 4.9 6.2 0.0 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF4201 PF13870.1 KFX91934.1 - 0.4 10.0 29.3 1.5 8.2 20.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Spectrin PF00435.16 KFX91934.1 - 0.45 10.8 26.4 1.8 8.8 13.4 2.8 1 1 1 2 2 2 0 Spectrin repeat HlyD PF00529.15 KFX91934.1 - 0.52 9.5 9.9 0.71 9.1 6.9 1.1 1 0 0 1 1 1 0 HlyD family secretion protein MAD PF05557.8 KFX91934.1 - 0.52 8.3 28.5 1 7.3 11.0 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein bZIP_2 PF07716.10 KFX91934.1 - 0.54 10.1 35.6 0.13 12.1 3.3 5.2 3 1 3 6 6 6 0 Basic region leucine zipper Cortex-I_coil PF09304.5 KFX91934.1 - 0.56 10.2 27.0 5.4 7.1 5.2 3.2 1 1 2 3 3 3 0 Cortexillin I, coiled coil NPV_P10 PF05531.7 KFX91934.1 - 0.58 10.4 10.6 19 5.5 0.0 3.1 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF904 PF06005.7 KFX91934.1 - 0.62 10.3 38.4 4.8 7.5 5.9 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF904) Spc7 PF08317.6 KFX91934.1 - 0.69 8.5 27.2 0.14 10.8 10.0 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.3 KFX91934.1 - 0.74 9.6 34.5 5 7.0 5.1 3.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Cep57_CLD_2 PF14197.1 KFX91934.1 - 0.76 9.7 32.1 0.63 10.0 4.5 4.1 1 1 2 3 3 2 0 Centrosome localisation domain of PPC89 DUF972 PF06156.8 KFX91934.1 - 0.77 10.1 27.2 1.4 9.2 9.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) HOOK PF05622.7 KFX91934.1 - 0.78 7.4 25.4 1 7.0 17.6 1.2 1 0 0 1 1 1 0 HOOK protein HalX PF08663.5 KFX91934.1 - 0.8 9.7 18.6 7.3 6.6 0.1 4.2 2 2 2 4 4 4 0 HalX domain DUF812 PF05667.6 KFX91934.1 - 0.81 8.1 26.3 0.85 8.0 8.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) PilJ PF13675.1 KFX91934.1 - 0.83 9.9 11.6 1.6 9.0 1.9 2.8 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term HAP1_N PF04849.8 KFX91934.1 - 0.89 8.4 28.2 34 3.2 19.6 3.0 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Striatin PF08232.7 KFX91934.1 - 0.98 9.7 25.0 0.95 9.7 12.0 2.2 1 1 1 2 2 2 0 Striatin family DUF3450 PF11932.3 KFX91934.1 - 1 8.5 22.0 1 8.5 6.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) SPX PF03105.14 KFX91934.1 - 1.1 9.0 16.0 1.4 8.6 11.1 1.2 1 0 0 1 1 1 0 SPX domain FlaC_arch PF05377.6 KFX91934.1 - 1.2 9.0 18.8 1.3 8.9 1.7 4.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF4200 PF13863.1 KFX91934.1 - 1.2 9.0 32.3 3.7 7.5 12.7 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF1664 PF07889.7 KFX91934.1 - 1.4 8.7 14.3 3.8 7.3 2.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CCDC155 PF14662.1 KFX91934.1 - 1.7 8.1 31.6 1.2 8.6 10.4 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DUF3287 PF11690.3 KFX91934.1 - 1.9 8.5 11.8 1.3 9.1 3.0 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) Fib_alpha PF08702.5 KFX91934.1 - 2.1 8.4 18.0 2.5 8.1 3.8 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family TPR_MLP1_2 PF07926.7 KFX91934.1 - 2.2 8.0 32.3 2.3 7.9 7.2 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF745 PF05335.8 KFX91934.1 - 2.5 7.6 19.5 0.22 11.0 1.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Syntaxin-6_N PF09177.6 KFX91934.1 - 2.7 8.4 17.5 13 6.2 4.4 2.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Mnd1 PF03962.10 KFX91934.1 - 3 7.4 29.0 6.5 6.3 8.8 2.1 1 1 1 2 2 2 0 Mnd1 family Lebercilin PF15619.1 KFX91934.1 - 3.2 7.1 31.8 82 2.5 11.9 2.1 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease HSP70 PF00012.15 KFX91934.1 - 3.3 5.5 19.5 4.1 5.1 13.5 1.2 1 0 0 1 1 1 0 Hsp70 protein Fmp27_WPPW PF10359.4 KFX91934.1 - 3.9 5.7 24.0 0.37 9.1 5.7 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain CDC37_N PF03234.9 KFX91934.1 - 4 7.7 24.3 1.1e+02 3.0 16.8 2.4 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding FlaF PF07309.6 KFX91934.1 - 4.4 7.2 9.0 0.46 10.3 1.0 2.5 1 1 2 3 3 3 0 Flagellar protein FlaF Cep57_MT_bd PF06657.8 KFX91934.1 - 4.5 7.3 19.9 0.33 10.9 2.1 3.5 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Orbi_VP5 PF00901.12 KFX91934.1 - 4.5 5.3 18.3 2.9 5.9 11.7 1.3 1 1 0 1 1 1 0 Orbivirus outer capsid protein VP5 STAT_alpha PF01017.15 KFX91934.1 - 4.9 6.8 18.6 2.5 7.7 0.2 2.3 1 1 1 2 2 2 0 STAT protein, all-alpha domain Prefoldin PF02996.12 KFX91934.1 - 5 6.7 28.2 2 8.0 3.2 4.0 1 1 3 4 4 4 0 Prefoldin subunit OmpH PF03938.9 KFX91934.1 - 5.7 6.8 28.7 2.7e+03 -1.9 19.9 2.2 1 1 0 1 1 0 0 Outer membrane protein (OmpH-like) DUF342 PF03961.8 KFX91934.1 - 7.1 4.9 26.1 0.79 8.0 5.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF4140 PF13600.1 KFX91934.1 - 7.2 7.1 21.0 66 4.0 0.1 3.3 1 1 1 2 2 1 0 N-terminal domain of unknown function (DUF4140) Nup54 PF13874.1 KFX91934.1 - 8.5 6.0 23.3 10 5.7 1.9 3.0 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 DUF4559 PF15112.1 KFX91934.1 - 8.5 5.4 20.1 15 4.6 13.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) Vps26 PF03643.10 KFX91940.1 - 4.3e-128 425.8 0.7 5e-128 425.6 0.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 KFX91940.1 - 0.0011 18.7 0.7 3.4 7.4 0.0 3.4 2 1 2 4 4 4 2 Arrestin (or S-antigen), N-terminal domain KilA-N PF04383.8 KFX91943.1 - 0.00036 20.1 0.0 0.0048 16.5 0.0 2.5 1 1 0 1 1 1 1 KilA-N domain Ric8 PF10165.4 KFX91951.1 - 5.1e-47 160.7 3.0 1.8e-44 152.3 2.1 2.0 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn RNase_H2-Ydr279 PF09468.5 KFX91951.1 - 0.00044 19.5 5.3 0.00054 19.2 3.7 1.1 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Spore_coat_CotO PF14153.1 KFX91951.1 - 0.0076 15.7 9.0 0.011 15.1 6.3 1.2 1 0 0 1 1 1 1 Spore coat protein CotO NARP1 PF12569.3 KFX91951.1 - 0.021 13.6 7.0 0.03 13.1 4.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GAGA_bind PF06217.7 KFX91951.1 - 0.26 11.2 5.5 0.36 10.7 3.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Vfa1 PF08432.5 KFX91951.1 - 0.26 11.2 13.3 0.42 10.6 9.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1510 PF07423.6 KFX91951.1 - 0.56 9.5 11.2 0.74 9.1 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RP-C_C PF11800.3 KFX91951.1 - 4 7.0 7.1 1.3 8.6 3.2 1.4 2 0 0 2 2 2 0 Replication protein C C-terminal region Med19 PF10278.4 KFX91951.1 - 8.3 6.0 15.7 48 3.5 10.3 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF4246 PF14033.1 KFX91968.1 - 8.7e-22 77.4 0.5 8.7e-22 77.4 0.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4246) Phage_Cox PF10743.4 KFX91968.1 - 0.05 13.6 1.9 0.12 12.4 0.3 2.2 2 0 0 2 2 2 0 Regulatory phage protein cox DUF2271 PF10029.4 KFX91968.1 - 0.077 12.4 0.0 0.077 12.4 0.0 2.2 2 0 0 2 2 2 0 Predicted periplasmic protein (DUF2271) CG-1 PF03859.11 KFX91988.1 - 0.037 13.5 0.4 0.054 13.0 0.3 1.2 1 0 0 1 1 1 0 CG-1 domain CsgE PF10627.4 KFX91988.1 - 0.21 11.4 2.1 0.33 10.7 1.5 1.4 1 0 0 1 1 1 0 Curli assembly protein CsgE Secretin_N_2 PF07655.8 KFX91988.1 - 4.9 7.6 15.5 0.73 10.2 7.8 1.7 2 0 0 2 2 2 0 Secretin N-terminal domain Ribosomal_S13 PF00416.17 KFX91989.1 - 3.1e-41 140.1 1.6 3.7e-41 139.8 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 KFX91989.1 - 0.0022 16.5 0.0 0.0029 16.2 0.0 1.3 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 KFX91989.1 - 0.088 12.8 0.2 0.34 10.9 0.0 2.0 1 1 0 2 2 2 0 Helix-hairpin-helix motif SBDS_C PF09377.5 KFX91990.1 - 2.7e-48 162.8 0.2 4.6e-48 162.0 0.1 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 KFX91990.1 - 2.2e-30 104.2 1.3 4e-30 103.4 0.9 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Peptidase_S10 PF00450.17 KFX91991.1 - 8.3e-129 430.3 1.0 1.1e-128 430.0 0.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 KFX91991.1 - 6.8e-10 39.0 0.1 1.2e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide RNA_pol_Rpb2_6 PF00562.23 KFX91993.1 - 1.8e-84 283.7 0.0 4e-84 282.6 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KFX91993.1 - 4.5e-53 179.2 0.1 6.7e-53 178.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KFX91993.1 - 1.5e-29 102.7 0.0 6.2e-29 100.7 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 KFX91993.1 - 1.3e-19 69.6 0.0 2.5e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 KFX91993.1 - 1.3e-19 69.7 0.0 3.9e-19 68.2 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.12 KFX91993.1 - 2.1e-12 46.8 0.2 4.7e-12 45.6 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 KFX91993.1 - 0.017 13.5 0.1 0.028 12.7 0.1 1.2 1 0 0 1 1 1 0 Baculovirus Y142 protein Sugar_tr PF00083.19 KFX91994.1 - 1.7e-87 293.9 29.3 2.2e-87 293.5 20.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX91994.1 - 1.5e-14 53.4 47.4 9.6e-10 37.6 9.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 KFX91995.1 - 3e-19 69.8 0.0 3.6e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX91995.1 - 5.1e-07 29.5 0.1 6.4e-07 29.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Sua5_yciO_yrdC PF01300.13 KFX91996.1 - 4.4e-16 58.6 0.0 6.1e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination LysM PF01476.15 KFX91998.1 - 5.4e-24 83.8 0.0 0.0011 18.8 0.0 5.9 6 0 0 6 6 6 5 LysM domain Glyco_hydro_18 PF00704.23 KFX91999.1 - 1.7e-76 257.9 0.1 2.1e-76 257.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KFX91999.1 - 4e-07 29.8 9.8 4e-07 29.8 6.8 2.7 2 1 0 2 2 2 1 Chitin recognition protein DUF2622 PF11080.3 KFX91999.1 - 0.032 14.0 0.0 0.068 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2622) Astacin PF01400.19 KFX92000.1 - 1.2e-09 37.8 5.3 0.0007 19.0 0.3 3.3 3 0 0 3 3 3 2 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.19 KFX92000.1 - 0.12 12.1 5.6 0.16 11.7 0.2 2.8 2 1 1 3 3 3 0 Matrixin Reprolysin_4 PF13583.1 KFX92000.1 - 0.13 11.8 0.1 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Mito_carr PF00153.22 KFX92001.1 - 5.1e-46 154.3 1.0 4.1e-15 55.2 0.2 3.6 2 1 1 3 3 3 3 Mitochondrial carrier protein Lipase_GDSL_2 PF13472.1 KFX92001.1 - 4.5e-11 43.1 0.0 1.7e-10 41.3 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFX92001.1 - 3.7e-08 33.4 0.2 1.1e-06 28.6 0.0 2.7 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Methyltransf_26 PF13659.1 KFX92001.1 - 0.01 15.8 0.1 0.19 11.7 0.0 2.9 3 1 0 3 3 3 0 Methyltransferase domain UBA PF00627.26 KFX92002.1 - 8.4e-06 25.4 0.0 1.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain Methyltransf_31 PF13847.1 KFX92015.1 - 9.1e-13 48.0 0.0 1.5e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFX92015.1 - 1.8e-11 43.7 0.0 2.6e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KFX92015.1 - 7e-10 38.9 0.0 3.3e-09 36.8 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX92015.1 - 1.5e-09 38.4 0.0 3.6e-09 37.1 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX92015.1 - 3.7e-08 33.7 0.0 9.1e-08 32.4 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain PRMT5 PF05185.11 KFX92015.1 - 4.3e-08 32.5 0.0 6.2e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_9 PF08003.6 KFX92015.1 - 1.1e-06 27.6 0.1 1.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 KFX92015.1 - 1.7e-06 27.5 0.5 3.8e-06 26.4 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KFX92015.1 - 2.8e-06 27.1 0.0 5.9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX92015.1 - 1.2e-05 25.6 0.1 0.00011 22.4 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 KFX92015.1 - 1.7e-05 24.0 0.1 2.6e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 KFX92015.1 - 7.1e-05 23.2 0.0 0.00015 22.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KFX92015.1 - 0.00012 22.1 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 KFX92015.1 - 0.00082 18.8 0.2 0.0012 18.3 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.13 KFX92015.1 - 0.003 17.1 0.1 0.0055 16.2 0.1 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 KFX92015.1 - 0.0078 15.8 0.1 0.032 13.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 KFX92015.1 - 0.0081 15.7 0.1 0.013 15.0 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 KFX92015.1 - 0.017 14.4 0.1 0.027 13.7 0.1 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Met_10 PF02475.11 KFX92015.1 - 0.018 14.6 0.1 0.03 13.8 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_4 PF02390.12 KFX92015.1 - 0.026 13.5 0.1 0.046 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 KFX92015.1 - 0.029 13.5 0.1 0.056 12.6 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB RrnaAD PF00398.15 KFX92015.1 - 0.068 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.1 KFX92015.1 - 0.1 13.4 0.0 0.21 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Per1 PF04080.8 KFX92016.1 - 1.6e-105 352.3 7.3 2e-105 352.0 5.1 1.1 1 0 0 1 1 1 1 Per1-like DEAD PF00270.24 KFX92017.1 - 1.8e-44 151.2 0.0 2.6e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX92017.1 - 2.1e-26 91.5 0.0 4.1e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX92017.1 - 0.0019 18.0 0.0 0.0066 16.2 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Brix PF04427.13 KFX92018.1 - 2.1e-57 193.8 0.0 2.9e-57 193.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain Pox_Ag35 PF03286.9 KFX92018.1 - 0.51 9.8 11.8 1 8.8 8.2 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein D-ser_dehydrat PF14031.1 KFX92028.1 - 5.4e-07 29.7 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Cellulase-like PF12876.2 KFX92028.1 - 0.15 12.5 0.2 3.2 8.2 0.0 2.2 1 1 1 2 2 2 0 Sugar-binding cellulase-like DUF755 PF05501.6 KFX92029.1 - 6.9 6.7 10.7 19 5.3 7.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF3926 PF13080.1 KFX92031.1 - 0.17 11.4 1.5 18 4.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3926) Laminin_II PF06009.7 KFX92031.1 - 0.75 9.5 8.9 0.82 9.4 4.9 1.9 1 1 1 2 2 2 0 Laminin Domain II Lebercilin PF15619.1 KFX92031.1 - 1.8 7.9 28.5 3.4 7.0 7.6 3.3 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Glyco_hydro_18 PF00704.23 KFX92035.1 - 6.7e-19 68.5 1.3 6.8e-18 65.2 0.1 2.3 1 1 0 2 2 2 1 Glycosyl hydrolases family 18 DUF946 PF06101.6 KFX92036.1 - 1.6e-05 23.1 0.0 2.3e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) GFO_IDH_MocA PF01408.17 KFX92040.1 - 5e-18 65.7 0.4 9.3e-18 64.8 0.3 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 KFX92040.1 - 0.016 15.6 0.0 0.037 14.4 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_3 PF03447.11 KFX92040.1 - 0.03 14.6 0.2 0.066 13.6 0.1 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Ank_2 PF12796.2 KFX92043.1 - 2.4e-39 133.5 0.1 2.4e-09 37.4 0.0 6.4 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFX92043.1 - 5.9e-34 115.8 2.8 0.00014 22.2 0.0 8.4 6 2 2 8 8 8 6 Ankyrin repeats (many copies) Ank PF00023.25 KFX92043.1 - 3.2e-31 105.5 9.7 0.00023 20.7 0.2 11.2 12 0 0 12 12 12 9 Ankyrin repeat Ank_5 PF13857.1 KFX92043.1 - 2.1e-23 81.7 12.8 1.9e-05 24.7 0.3 7.6 5 1 3 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX92043.1 - 1e-22 77.9 7.1 0.036 14.3 0.1 9.7 9 1 0 9 9 9 7 Ankyrin repeat Ada_Zn_binding PF02805.11 KFX92044.1 - 4.7e-29 99.7 2.7 8.7e-29 98.9 1.9 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 KFX92044.1 - 1.2e-06 28.0 0.2 8.1e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 KFX92044.1 - 0.0031 17.5 0.0 0.007 16.4 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 KFX92044.1 - 0.09 12.9 0.0 0.33 11.1 0.0 2.0 1 1 0 1 1 1 0 Helix-turn-helix domain Dak2 PF02734.12 KFX92045.1 - 5.1e-44 150.0 4.4 5.9e-44 149.8 3.0 1.0 1 0 0 1 1 1 1 DAK2 domain LSM PF01423.17 KFX92046.1 - 2.9e-18 65.1 0.1 3.8e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain ECH_C PF13766.1 KFX92047.1 - 9e-37 125.8 0.0 8.2e-36 122.7 0.0 2.4 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KFX92047.1 - 2.7e-23 82.3 0.0 5.9e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family K_channel_TID PF07941.6 KFX92047.1 - 0.31 11.2 5.9 1.1 9.5 4.1 2.0 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF3591 PF12157.3 KFX92050.1 - 9e-195 647.3 1.6 1.2e-194 646.9 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 KFX92050.1 - 0.014 15.0 2.4 0.032 13.8 1.7 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 KFX92050.1 - 0.027 14.4 1.1 0.046 13.6 0.8 1.4 1 0 0 1 1 1 0 Zinc knuckle Meiotic_rec114 PF03525.9 KFX92050.1 - 0.098 11.1 1.8 0.38 9.2 0.5 2.0 2 0 0 2 2 2 0 Meiotic recombination protein rec114 ELO PF01151.13 KFX92054.1 - 1.4e-80 270.2 9.6 1.6e-80 269.9 6.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family MIF PF01187.13 KFX92055.1 - 6.5e-05 22.9 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) DUF3211 PF11485.3 KFX92055.1 - 0.042 13.8 0.3 0.042 13.8 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3211) DUF4110 PF13422.1 KFX92055.1 - 0.043 13.6 5.3 0.06 13.1 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) MARVEL PF01284.18 KFX92056.1 - 0.061 13.1 10.2 0.34 10.7 7.1 1.9 1 1 0 1 1 1 0 Membrane-associating domain DUF202 PF02656.10 KFX92056.1 - 0.62 10.3 5.7 0.18 12.0 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF202) GMC_oxred_N PF00732.14 KFX92057.1 - 1.8e-62 211.1 0.0 2.4e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFX92057.1 - 2.8e-33 115.2 0.0 4.7e-33 114.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KFX92057.1 - 9.1e-07 28.0 1.4 0.0051 15.7 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KFX92057.1 - 7.8e-05 21.7 2.5 0.0076 15.1 0.8 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX92057.1 - 0.0001 22.2 0.6 0.00031 20.7 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFX92057.1 - 0.00011 21.4 0.2 0.028 13.5 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Lycopene_cycl PF05834.7 KFX92057.1 - 0.00093 18.2 0.5 0.0018 17.2 0.3 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KFX92057.1 - 0.0081 16.0 0.1 0.022 14.6 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFX92057.1 - 0.027 12.9 0.6 0.051 12.0 0.4 1.4 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 KFX92057.1 - 0.11 12.2 0.3 0.25 11.0 0.2 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KFX92057.1 - 0.19 10.3 0.4 0.3 9.6 0.3 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Beta-lactamase PF00144.19 KFX92058.1 - 9.8e-15 54.3 0.0 1.3e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 KFX92058.1 - 0.06 12.6 0.0 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Hce2 PF14856.1 KFX92067.1 - 7.3e-16 57.8 0.0 1e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor GST_N_3 PF13417.1 KFX92068.1 - 3.7e-11 43.0 0.1 7.3e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFX92068.1 - 7.4e-08 32.2 0.0 1.7e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFX92068.1 - 5.7e-07 29.4 0.0 9.7e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFX92068.1 - 0.00013 21.8 0.1 0.00033 20.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFX92068.1 - 0.0013 18.8 0.0 0.0024 18.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KFX92068.1 - 0.036 14.5 0.0 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pec_lyase_C PF00544.14 KFX92069.1 - 2.7e-43 147.7 10.0 3.9e-43 147.2 6.9 1.2 1 0 0 1 1 1 1 Pectate lyase SH3_3 PF08239.6 KFX92070.1 - 0.0072 16.4 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain DUF1992 PF09350.5 KFX92071.1 - 1e-16 60.5 0.2 1.4e-15 56.8 0.1 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1992) Trypan_PARP PF05887.6 KFX92071.1 - 0.011 15.5 1.5 0.023 14.4 1.0 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pex14_N PF04695.8 KFX92071.1 - 2.3 8.2 7.8 1.3 9.0 0.9 2.7 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1049 PF06305.6 KFX92072.1 - 0.17 11.3 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Pet191_N PF10203.4 KFX92072.1 - 9.3 6.3 7.6 8.1 6.5 0.1 2.9 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Inhibitor_I78 PF11720.3 KFX92073.1 - 4.2e-14 52.0 0.0 2.1e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 Peptidase inhibitor I78 family potato_inhibit PF00280.13 KFX92073.1 - 0.0089 16.1 0.0 0.075 13.1 0.0 2.2 2 0 0 2 2 2 1 Potato inhibitor I family PUA PF01472.15 KFX92074.1 - 1.5e-13 50.2 0.3 5.2e-13 48.5 0.2 1.8 1 1 0 1 1 1 1 PUA domain TFIID-31kDa PF02291.10 KFX92075.1 - 8.2e-30 103.2 0.0 3.5e-29 101.1 0.0 1.8 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histidinol_dh PF00815.15 KFX92076.1 - 1.1e-176 587.5 5.1 1.7e-176 586.9 3.5 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 KFX92076.1 - 3.5e-24 84.2 0.1 7.1e-24 83.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase TPR_11 PF13414.1 KFX92076.1 - 5e-18 64.5 3.6 9.5e-15 54.0 0.6 2.8 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KFX92076.1 - 8.1e-12 44.1 2.4 0.00023 20.8 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFX92076.1 - 1.1e-10 40.6 0.5 0.0012 18.3 0.0 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat PRA-PH PF01503.12 KFX92076.1 - 2.8e-10 40.3 0.3 8.7e-10 38.7 0.2 1.9 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase TPR_16 PF13432.1 KFX92076.1 - 6.8e-08 32.9 6.0 5.8e-07 30.0 0.8 3.1 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFX92076.1 - 1.5e-05 25.2 2.8 0.14 12.8 0.3 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFX92076.1 - 4.8e-05 23.2 0.1 0.54 10.6 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFX92076.1 - 0.00034 20.4 1.6 0.93 9.4 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFX92076.1 - 0.0015 18.1 0.0 2.6 8.0 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFX92076.1 - 0.0015 18.8 0.9 0.0056 16.9 0.4 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.12 KFX92076.1 - 0.0084 16.4 0.5 2.8 8.2 0.0 2.6 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_8 PF13181.1 KFX92076.1 - 0.025 14.3 0.7 0.33 10.8 0.1 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat XPC-binding PF09280.6 KFX92076.1 - 0.069 12.6 5.4 0.033 13.6 1.8 1.8 2 0 0 2 2 2 0 XPC-binding domain TPR_9 PF13371.1 KFX92076.1 - 0.082 12.7 0.4 0.41 10.5 0.1 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat MazG PF03819.12 KFX92076.1 - 0.094 12.6 1.1 0.27 11.1 0.7 1.8 2 0 0 2 2 1 0 MazG nucleotide pyrophosphohydrolase domain ABC_tran PF00005.22 KFX92077.1 - 5.7e-34 117.3 0.0 1.4e-33 116.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KFX92077.1 - 7.8e-19 68.1 1.7 1.8e-18 66.9 1.2 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 KFX92077.1 - 1.2e-06 27.8 0.0 0.00011 21.5 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFX92077.1 - 7.9e-06 26.0 0.7 0.0014 18.6 0.0 2.8 2 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KFX92077.1 - 0.0006 19.8 0.1 0.0017 18.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KFX92077.1 - 0.0016 17.6 0.0 0.0056 15.8 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFX92077.1 - 0.0032 16.9 0.2 0.0095 15.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KFX92077.1 - 0.0038 17.3 0.1 0.019 15.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFX92077.1 - 0.0053 17.5 1.0 0.014 16.1 0.0 2.3 3 0 0 3 3 1 1 AAA domain Zeta_toxin PF06414.7 KFX92077.1 - 0.0054 15.8 0.0 0.021 13.9 0.0 2.0 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KFX92077.1 - 0.0077 16.5 0.7 0.04 14.2 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.1 KFX92077.1 - 0.018 14.6 1.0 0.75 9.3 0.1 3.0 2 1 0 2 2 2 0 AAA domain DEAD PF00270.24 KFX92077.1 - 0.019 14.4 0.0 0.05 13.0 0.0 1.6 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_5 PF07728.9 KFX92077.1 - 0.023 14.4 0.0 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 KFX92077.1 - 0.025 14.9 1.2 0.037 14.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain SbcCD_C PF13558.1 KFX92077.1 - 0.041 13.8 0.3 0.22 11.4 0.2 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 KFX92077.1 - 0.065 12.6 0.3 1.9 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_25 PF13481.1 KFX92077.1 - 0.086 12.2 0.1 0.99 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF2207 PF09972.4 KFX92077.1 - 0.22 10.0 1.8 0.86 8.1 0.1 2.6 3 1 1 4 4 4 0 Predicted membrane protein (DUF2207) YchF-GTPase_C PF06071.8 KFX92078.1 - 1.1e-34 118.0 0.3 1.3e-34 117.8 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF933) TGS PF02824.16 KFX92078.1 - 6.2e-05 22.7 0.0 7.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 TGS domain GFA PF04828.9 KFX92079.1 - 1.3e-21 76.2 4.1 5.8e-10 38.9 0.1 2.4 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Rpr2 PF04032.11 KFX92079.1 - 0.079 12.8 2.5 2.9 7.8 0.0 3.0 3 0 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Transpos_assoc PF13963.1 KFX92079.1 - 0.66 10.0 3.3 8.7 6.4 0.2 2.6 2 0 0 2 2 2 0 Transposase-associated domain NOB1_Zn_bind PF08772.6 KFX92079.1 - 3 7.7 10.4 4.3 7.2 0.0 3.7 4 0 0 4 4 4 0 Nin one binding (NOB1) Zn-ribbon like TPR_10 PF13374.1 KFX92080.1 - 1.4e-91 298.1 5.9 3e-13 49.2 0.0 8.1 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.1 KFX92080.1 - 4.9e-74 244.2 6.6 2e-21 75.6 0.1 5.4 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 KFX92080.1 - 6.1e-34 115.4 5.4 3e-10 39.5 0.2 5.2 3 1 2 5 5 5 5 TPR repeat TPR_1 PF00515.23 KFX92080.1 - 8.9e-29 97.8 22.3 9.5e-05 21.8 0.1 7.9 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.1 KFX92080.1 - 7.2e-27 91.0 12.7 0.0029 17.3 0.0 7.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 KFX92080.1 - 3.3e-24 82.8 26.3 0.00097 18.8 0.1 8.5 9 0 0 9 9 7 7 Tetratricopeptide repeat TPR_16 PF13432.1 KFX92080.1 - 5.3e-23 81.1 13.3 3.6e-06 27.5 0.5 6.4 4 1 3 7 7 7 6 Tetratricopeptide repeat Patatin PF01734.17 KFX92080.1 - 8.7e-23 81.3 0.0 1.8e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_8 PF13181.1 KFX92080.1 - 2e-13 49.0 15.8 0.036 13.8 0.1 7.8 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFX92080.1 - 2.1e-12 46.5 14.6 0.15 12.8 0.0 8.4 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFX92080.1 - 1.4e-11 43.5 4.9 1.3 9.3 0.0 7.4 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_3 PF07720.7 KFX92080.1 - 1.5e-10 40.5 19.1 0.031 14.0 0.0 8.3 8 0 0 8 8 8 2 Tetratricopeptide repeat Apc3 PF12895.2 KFX92080.1 - 1.7e-09 37.7 3.4 0.0025 17.9 0.1 5.1 2 1 4 6 6 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 KFX92080.1 - 3.8e-09 36.1 2.1 19 6.0 0.0 8.1 8 0 0 8 8 7 0 Tetratricopeptide repeat PPR PF01535.15 KFX92080.1 - 1.4e-08 34.1 0.6 8.1 6.6 0.0 7.4 7 0 0 7 7 7 0 PPR repeat FTCD PF02971.9 KFX92080.1 - 3.2e-07 30.0 0.6 0.72 9.4 0.0 4.6 1 1 3 5 5 5 3 Formiminotransferase domain TPR_19 PF14559.1 KFX92080.1 - 1.4e-05 25.3 21.9 0.012 15.9 0.3 6.5 5 1 1 6 6 6 1 Tetratricopeptide repeat Rab5-bind PF09311.6 KFX92080.1 - 0.0024 17.8 13.7 2.2 8.1 0.3 4.9 2 1 3 5 5 5 2 Rabaptin-like protein DEP PF00610.16 KFX92080.1 - 0.02 14.5 0.0 0.1 12.3 0.0 2.3 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF1925 PF09094.6 KFX92080.1 - 0.033 14.1 5.3 68 3.5 0.1 5.1 4 2 1 5 5 5 0 Domain of unknown function (DUF1925) RHH_2 PF03693.9 KFX92080.1 - 0.035 14.2 0.2 36 4.6 0.0 4.1 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0156) TPR_6 PF13174.1 KFX92080.1 - 0.066 13.6 19.8 10 6.8 0.2 7.6 8 1 0 8 8 7 0 Tetratricopeptide repeat TPR_5 PF12688.2 KFX92080.1 - 0.11 12.5 5.6 0.65 10.0 0.8 3.3 2 2 1 3 3 3 0 Tetratrico peptide repeat 4HB_MCP_1 PF12729.2 KFX92080.1 - 0.77 9.0 14.0 11 5.3 0.0 6.0 6 1 1 7 7 7 0 Four helix bundle sensory module for signal transduction MIT PF04212.13 KFX92080.1 - 2.2 8.2 23.9 0.72 9.7 0.2 7.3 7 2 2 9 9 8 0 MIT (microtubule interacting and transport) domain DUF1180 PF06679.7 KFX92081.1 - 0.14 12.0 4.0 0.16 11.8 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF1517 PF07466.6 KFX92081.1 - 1.2 8.0 4.1 1.5 7.7 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Ferritin_2 PF13668.1 KFX92082.1 - 4.7e-45 152.8 3.3 8.8e-45 152.0 2.3 1.5 1 0 0 1 1 1 1 Ferritin-like domain MFS_1 PF07690.11 KFX92084.1 - 4.2e-16 58.6 37.7 1.4e-09 37.1 3.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MOR2-PAG1_N PF14222.1 KFX92094.1 - 8.1e-218 724.5 0.0 1.8e-217 723.4 0.0 1.6 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 KFX92094.1 - 4.4e-91 305.2 0.1 1.2e-90 303.8 0.1 1.8 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 KFX92094.1 - 2.2e-33 115.0 7.7 7.4e-12 43.7 0.0 3.9 3 1 1 4 4 4 3 Cell morphogenesis central region HEAT_2 PF13646.1 KFX92094.1 - 0.0027 17.9 1.1 0.29 11.4 0.0 4.9 6 0 0 6 6 6 1 HEAT repeats HEAT PF02985.17 KFX92094.1 - 0.0056 16.6 0.5 3.2 8.0 0.0 4.6 5 0 0 5 5 5 1 HEAT repeat Cid2 PF09774.4 KFX92103.1 - 1.1e-09 38.5 0.0 1.5e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 GDA1_CD39 PF01150.12 KFX92103.1 - 0.16 10.4 0.0 0.17 10.3 0.0 1.0 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family Mito_carr PF00153.22 KFX92104.1 - 8.2e-46 153.6 0.5 2e-18 65.8 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein JAB PF01398.16 KFX92106.1 - 7e-08 32.2 0.5 7e-07 28.9 0.4 2.1 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease AdoHcyase PF05221.12 KFX92107.1 - 4.6e-137 455.3 0.2 5.3e-137 455.1 0.2 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KFX92107.1 - 5.6e-83 276.6 3.2 8.5e-83 276.0 2.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KFX92107.1 - 1.8e-07 30.4 0.1 4.1e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 KFX92107.1 - 0.00061 19.4 0.7 0.0013 18.3 0.4 1.7 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.7 KFX92107.1 - 0.0012 18.2 0.5 0.0022 17.3 0.3 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TMEM107 PF14995.1 KFX92107.1 - 0.0065 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Transmembrane protein TrkA_N PF02254.13 KFX92107.1 - 0.078 12.9 0.1 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 KFX92107.1 - 0.089 12.4 0.5 0.17 11.5 0.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA_2 PF07724.9 KFX92108.1 - 3.9e-46 157.0 0.3 7.6e-45 152.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 KFX92108.1 - 4.8e-26 90.4 0.3 4.8e-26 90.4 0.2 2.2 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KFX92108.1 - 2.3e-20 73.1 0.1 1.4e-10 41.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFX92108.1 - 2.7e-13 49.8 0.0 6.5e-09 35.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFX92108.1 - 5.3e-10 39.5 12.2 0.00032 20.7 0.0 5.3 4 3 1 6 6 5 3 AAA ATPase domain AAA_22 PF13401.1 KFX92108.1 - 1.4e-09 38.1 0.0 0.0016 18.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 KFX92108.1 - 5.1e-08 32.5 0.3 2e-05 24.1 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 KFX92108.1 - 1.7e-07 31.0 0.0 0.014 15.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain Arch_ATPase PF01637.13 KFX92108.1 - 2e-07 30.9 1.7 0.084 12.5 0.7 4.3 3 2 0 3 3 2 2 Archaeal ATPase AAA_14 PF13173.1 KFX92108.1 - 8.7e-06 25.6 0.0 0.074 12.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KFX92108.1 - 9.3e-06 25.1 0.1 0.12 11.8 0.0 2.7 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_17 PF13207.1 KFX92108.1 - 1.8e-05 25.5 3.9 0.027 15.2 0.1 3.6 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KFX92108.1 - 3.5e-05 23.4 0.0 0.056 13.1 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 KFX92108.1 - 5.7e-05 23.4 5.8 0.14 12.4 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_28 PF13521.1 KFX92108.1 - 8.2e-05 22.6 0.6 0.062 13.2 0.0 3.6 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 KFX92108.1 - 0.0008 19.1 0.1 0.76 9.4 0.0 3.1 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KFX92108.1 - 0.00083 19.6 0.3 0.85 9.9 0.0 3.3 3 0 0 3 3 3 1 ABC transporter RNA_helicase PF00910.17 KFX92108.1 - 0.0014 18.7 0.1 0.75 9.9 0.0 3.0 3 1 0 3 3 2 1 RNA helicase Mg_chelatase PF01078.16 KFX92108.1 - 0.0016 17.6 0.0 0.64 9.1 0.0 2.9 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI IncA PF04156.9 KFX92108.1 - 0.0017 18.0 9.2 0.0017 18.0 6.4 1.8 2 0 0 2 2 1 1 IncA protein AAA_10 PF12846.2 KFX92108.1 - 0.0021 17.5 0.7 0.035 13.5 0.0 3.1 2 2 1 3 3 2 1 AAA-like domain AAA_25 PF13481.1 KFX92108.1 - 0.0021 17.5 0.0 0.42 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 KFX92108.1 - 0.0037 16.2 0.1 0.078 11.8 0.1 3.1 4 1 0 4 4 4 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 KFX92108.1 - 0.0043 16.1 0.0 0.13 11.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.1 KFX92108.1 - 0.0051 16.4 1.8 0.35 10.4 0.0 3.9 4 1 0 4 4 4 1 AAA domain DUF258 PF03193.11 KFX92108.1 - 0.0053 15.9 0.0 2.6 7.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 PhoH PF02562.11 KFX92108.1 - 0.0056 15.9 0.0 0.97 8.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.1 KFX92108.1 - 0.011 15.6 0.0 4.8 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain Mnd1 PF03962.10 KFX92108.1 - 0.011 15.3 10.0 0.023 14.3 6.9 1.4 1 0 0 1 1 1 0 Mnd1 family Miro PF08477.8 KFX92108.1 - 0.016 15.6 0.1 0.23 11.9 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein ResIII PF04851.10 KFX92108.1 - 0.022 14.6 0.2 8.2 6.2 0.0 3.0 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.4 KFX92108.1 - 0.022 13.3 0.1 2.2 6.7 0.0 2.7 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.1 KFX92108.1 - 0.023 14.2 0.0 2.3 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 KFX92108.1 - 0.025 14.0 0.0 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PIF1 PF05970.9 KFX92108.1 - 0.041 12.8 0.0 2.1 7.2 0.0 2.5 3 0 0 3 3 2 0 PIF1-like helicase UPF0079 PF02367.12 KFX92108.1 - 0.058 13.0 0.0 13 5.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 KFX92108.1 - 0.075 12.5 0.0 4.5 6.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain NB-ARC PF00931.17 KFX92108.1 - 0.092 11.5 0.0 8.1 5.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain DNA_pol3_delta2 PF13177.1 KFX92108.1 - 0.12 12.0 0.0 1.1 8.9 0.0 2.4 3 0 0 3 3 2 0 DNA polymerase III, delta subunit Zw10 PF06248.8 KFX92108.1 - 0.15 10.1 1.7 0.3 9.1 0.7 1.7 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 AAA_15 PF13175.1 KFX92108.1 - 0.22 10.5 0.0 0.38 9.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Atg14 PF10186.4 KFX92108.1 - 0.71 8.7 6.7 1.5 7.7 4.6 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 KFX92108.1 - 0.96 7.2 2.2 1.4 6.6 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.17 KFX92108.1 - 2.7 8.0 16.2 6.4 6.8 8.9 3.1 2 1 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain AAA_23 PF13476.1 KFX92108.1 - 6.1 7.1 18.8 16 5.7 0.0 3.4 2 1 0 2 2 1 0 AAA domain DUF4349 PF14257.1 KFX92108.1 - 9.4 5.3 13.3 2.8 7.1 1.7 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4349) EF1_GNE PF00736.14 KFX92109.1 - 3.5e-30 103.5 1.2 6.3e-30 102.7 0.8 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KFX92109.1 - 6.5e-14 51.7 8.0 6.5e-14 51.7 5.5 2.5 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 KFX92109.1 - 0.00032 21.1 0.1 0.00077 19.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFX92109.1 - 0.0054 16.6 0.6 0.02 14.8 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Cwf_Cwc_15 PF04889.7 KFX92109.1 - 0.13 11.9 1.7 0.18 11.4 1.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.6 KFX92113.1 - 8.3e-07 28.8 1.7 1.5e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 PPP4R2 ORC6 PF05460.8 KFX92113.1 - 1.5 7.8 5.5 3.1 6.7 3.8 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) tRNA-synt_2 PF00152.15 KFX92114.1 - 4e-96 321.7 0.0 2.1e-78 263.4 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KFX92114.1 - 2.5e-09 36.8 0.2 4.5e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KFX92114.1 - 3.2e-08 33.0 0.0 0.006 15.8 0.0 3.5 3 0 0 3 3 3 3 tRNA synthetases class II core domain (F) zf-Tim10_DDP PF02953.10 KFX92115.1 - 2e-22 78.2 0.8 2.4e-22 77.9 0.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tom5 PF10642.4 KFX92115.1 - 0.0053 16.3 1.4 0.017 14.7 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial import receptor subunit or translocase PG_binding_1 PF01471.13 KFX92116.1 - 9.7e-05 22.2 0.3 0.24 11.3 0.0 3.5 3 1 0 3 3 3 2 Putative peptidoglycan binding domain Spc7 PF08317.6 KFX92116.1 - 0.22 10.1 6.5 0.42 9.2 4.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein BLOC1_2 PF10046.4 KFX92116.1 - 0.7 10.0 8.0 6.2 7.0 4.5 2.5 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.1 KFX92116.1 - 1.1 7.6 5.9 1.6 7.1 4.1 1.1 1 0 0 1 1 1 0 AAA domain ERM PF00769.14 KFX92116.1 - 1.1 8.7 7.3 2 7.8 5.0 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family IncA PF04156.9 KFX92116.1 - 4.1 6.9 9.0 9.9 5.6 6.2 1.6 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 KFX92116.1 - 5.2 6.9 6.1 2.8 7.8 1.1 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding CLTH PF10607.4 KFX92117.1 - 3e-32 111.3 0.0 5.3e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KFX92117.1 - 2.3e-18 65.6 1.6 5.2e-18 64.4 1.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 KFX92117.1 - 1e-05 24.9 0.1 1.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 KFX92117.1 - 0.00029 20.5 0.4 0.0005 19.8 0.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFX92117.1 - 0.00072 19.5 1.0 0.0012 18.8 0.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX92117.1 - 0.00091 18.9 0.4 0.0015 18.1 0.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFX92117.1 - 0.0019 17.8 0.6 0.0033 17.0 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFX92117.1 - 0.042 13.7 0.3 0.094 12.6 0.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFX92117.1 - 0.052 13.2 0.9 0.095 12.3 0.7 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PH_6 PF15406.1 KFX92118.1 - 6e-37 126.1 0.9 6e-37 126.1 0.6 3.0 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.24 KFX92118.1 - 0.00031 20.9 0.0 0.00079 19.6 0.0 1.8 1 0 0 1 1 1 1 PH domain 2OG-FeII_Oxy PF03171.15 KFX92123.1 - 9.2e-16 57.9 0.0 1.4e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CBFD_NFYB_HMF PF00808.18 KFX92124.1 - 7.8e-10 38.6 0.0 1.6e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFX92124.1 - 3.7e-07 30.1 0.0 5.8e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KFX92124.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 Bromodomain associated PPE PF00823.14 KFX92124.1 - 0.018 14.9 0.2 0.029 14.2 0.1 1.3 1 0 0 1 1 1 0 PPE family CENP-S PF15630.1 KFX92124.1 - 0.1 12.7 0.1 0.43 10.7 0.0 2.0 1 1 1 2 2 2 0 Kinetochore component CENP-S Ank_2 PF12796.2 KFX92125.1 - 1.6e-29 102.1 0.0 2e-11 44.0 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFX92125.1 - 4.1e-23 79.9 0.5 7.1e-06 25.5 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeat Melibiase PF02065.13 KFX92125.1 - 7.2e-22 77.6 0.2 7.3e-17 61.1 0.0 3.1 1 1 1 2 2 2 2 Melibiase Fungal_trans PF04082.13 KFX92125.1 - 5.1e-20 71.4 0.0 1e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_4 PF13637.1 KFX92125.1 - 8.1e-19 67.6 0.4 5.1e-06 26.8 0.0 4.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX92125.1 - 1.5e-18 65.0 0.2 0.0021 18.1 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 KFX92125.1 - 5.4e-13 48.7 1.3 0.0072 16.5 0.1 5.7 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Zn_clus PF00172.13 KFX92125.1 - 1.3e-09 37.7 11.7 3.4e-09 36.4 8.1 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Alpha-amylase PF00128.19 KFX92126.1 - 5.4e-30 104.8 0.9 1.1e-29 103.7 0.6 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 KFX92126.1 - 0.00057 17.7 0.1 0.89 7.2 0.0 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.5 KFX92126.1 - 0.0029 17.4 0.2 0.0078 16.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1939) RNA_pol_3_Rpc31 PF11705.3 KFX92128.1 - 0.42 10.5 6.7 0.53 10.1 4.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CPSase_L_chain PF00289.17 KFX92134.1 - 0.0082 16.2 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain CBM_48 PF02922.13 KFX92134.1 - 0.047 13.7 0.1 0.099 12.7 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Ten1 PF12658.2 KFX92135.1 - 1e-25 89.9 0.0 1.2e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 KFX92135.1 - 9.8e-05 21.9 0.0 0.00027 20.4 0.0 1.8 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit SAM_decarbox PF01536.11 KFX92142.1 - 7.7e-89 297.6 0.0 1.3e-88 296.8 0.0 1.3 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase PAP_assoc PF03828.14 KFX92144.1 - 2.1e-16 59.6 0.0 1.5e-15 56.8 0.0 2.3 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KFX92144.1 - 0.00018 21.7 0.0 0.00097 19.4 0.0 2.3 2 0 0 2 2 2 1 Nucleotidyltransferase domain Retrotrans_gag PF03732.12 KFX92144.1 - 0.0005 20.0 0.1 0.32 11.1 0.0 2.8 2 0 0 2 2 2 2 Retrotransposon gag protein RGS-like PF09128.6 KFX92144.1 - 0.0041 16.6 0.2 0.0096 15.4 0.1 1.6 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain MFS_1 PF07690.11 KFX92147.1 - 5.1e-37 127.3 30.5 3.2e-28 98.4 3.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX92147.1 - 7.3e-08 31.4 10.4 7.3e-08 31.4 7.2 3.0 2 2 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KFX92147.1 - 0.0087 14.2 0.7 0.0087 14.2 0.5 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Peptidase_M28 PF04389.12 KFX92148.1 - 5.5e-17 62.0 0.0 1e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 KFX92148.1 - 6.4e-17 61.2 0.0 1.1e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 KFX92148.1 - 9e-05 22.1 0.2 0.00024 20.7 0.0 1.8 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.10 KFX92148.1 - 0.057 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Nicastrin IMPDH PF00478.20 KFX92154.1 - 8.7e-130 432.6 5.1 1.1e-129 432.3 3.5 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KFX92154.1 - 2.9e-16 58.9 0.0 5.4e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 KFX92154.1 - 3.9e-08 32.8 9.6 0.00027 20.1 0.0 2.5 2 1 1 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.13 KFX92154.1 - 2e-06 26.9 0.8 1e-05 24.5 0.3 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 KFX92154.1 - 0.022 14.0 1.7 0.8 8.9 0.1 2.3 1 1 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.9 KFX92154.1 - 0.034 13.1 0.2 0.066 12.1 0.1 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase RasGAP_C PF03836.10 KFX92155.1 - 2.1e-46 157.1 1.5 4.8e-46 155.9 1.1 1.7 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 KFX92155.1 - 1.1e-42 146.0 0.0 2.4e-42 144.8 0.0 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 KFX92155.1 - 1.3e-11 43.0 24.0 0.27 10.9 0.2 10.6 11 0 0 11 11 11 6 IQ calmodulin-binding motif CH PF00307.26 KFX92155.1 - 3.7e-10 39.7 0.0 9.2e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain GKAP PF03359.8 KFX92158.1 - 2.2 7.7 9.8 2.7 7.4 6.8 1.0 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein IER PF05760.7 KFX92158.1 - 2.6 7.9 10.2 3.1 7.6 7.1 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) DUF566 PF04484.7 KFX92158.1 - 9.6 5.6 11.0 12 5.3 7.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Pro_CA PF00484.14 KFX92160.1 - 1.3e-31 109.6 0.1 1.7e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Zn_clus PF00172.13 KFX92161.1 - 4.5e-09 36.0 7.3 4.5e-09 36.0 5.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX92161.1 - 1.1e-05 24.4 0.0 1.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF427 PF04248.7 KFX92163.1 - 3.8e-31 106.6 1.5 4.2e-31 106.4 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Pyridoxal_deC PF00282.14 KFX92164.1 - 6.2e-120 400.0 0.0 7.7e-120 399.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Got1 PF04178.7 KFX92165.1 - 1.7e-17 63.6 13.8 2e-17 63.3 9.5 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3185 PF11381.3 KFX92165.1 - 7.7 6.3 10.2 13 5.5 0.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) DUF3487 PF11990.3 KFX92165.1 - 8.3 5.8 9.6 0.3 10.4 1.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3487) YL1_C PF08265.6 KFX92166.1 - 1.5e-15 56.3 0.1 2.3e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DASH_Dad4 PF08650.5 KFX92167.1 - 1.3e-28 98.6 5.0 1.4e-28 98.5 3.5 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.12 KFX92167.1 - 0.0086 16.0 0.3 0.0098 15.8 0.2 1.1 1 0 0 1 1 1 1 Granulocyte-macrophage colony-stimulating factor DASH_Dad1 PF08649.5 KFX92167.1 - 0.029 14.0 3.2 0.036 13.7 2.2 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad1 Ank PF00023.25 KFX92169.1 - 0.022 14.5 0.2 0.067 13.0 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeat Choline_kinase PF01633.15 KFX92177.1 - 1.1e-17 64.3 0.1 1.6e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KFX92177.1 - 5.7e-06 26.2 0.0 9.6e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Git3_C PF11970.3 KFX92177.1 - 0.00085 19.0 0.5 0.0018 18.0 0.4 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Whi5 PF08528.6 KFX92182.1 - 4.1e-08 32.6 0.2 6.2e-08 32.0 0.2 1.3 1 0 0 1 1 1 1 Whi5 like DUF1768 PF08719.6 KFX92190.1 - 2.4e-34 118.3 0.0 5.9e-34 117.0 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1768) Vinculin PF01044.14 KFX92190.1 - 1 7.3 11.0 1.3 6.9 7.6 1.1 1 0 0 1 1 1 0 Vinculin family DDHD PF02862.12 KFX92190.1 - 5.2 6.8 14.6 8.2 6.1 10.1 1.3 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 KFX92190.1 - 7.4 6.3 24.1 13 5.6 16.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA PF00004.24 KFX92191.1 - 3.3e-40 137.3 0.0 7.1e-40 136.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFX92191.1 - 0.00025 21.0 0.7 0.018 15.0 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 KFX92191.1 - 0.00029 19.9 0.0 0.00059 18.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KFX92191.1 - 0.00032 20.4 0.6 0.0013 18.4 0.0 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFX92191.1 - 0.00033 20.7 0.3 0.02 15.0 0.0 3.0 2 1 1 3 3 2 1 AAA domain AAA_2 PF07724.9 KFX92191.1 - 0.00045 20.1 0.9 0.0047 16.8 0.0 2.9 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 KFX92191.1 - 0.0013 18.0 0.2 0.028 13.6 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 KFX92191.1 - 0.0086 15.2 0.0 0.024 13.8 0.0 1.7 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KFX92191.1 - 0.0099 15.7 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KFX92191.1 - 0.015 14.2 0.0 0.035 13.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 KFX92191.1 - 0.018 14.8 0.4 0.044 13.5 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 KFX92191.1 - 0.023 14.0 0.1 0.047 13.0 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 KFX92191.1 - 0.038 13.3 1.4 0.33 10.3 0.2 2.4 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 KFX92191.1 - 0.051 13.1 0.1 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KFX92191.1 - 0.075 13.8 0.1 0.075 13.8 0.1 2.7 2 2 0 2 2 2 0 AAA domain AAA_11 PF13086.1 KFX92191.1 - 0.19 11.2 2.1 0.6 9.6 0.0 2.4 2 2 0 2 2 2 0 AAA domain DUF2029 PF09594.5 KFX92194.1 - 0.33 10.4 3.0 0.44 10.0 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) SKG6 PF08693.5 KFX92194.1 - 0.51 9.7 2.3 0.87 8.9 1.6 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain YesK PF14150.1 KFX92194.1 - 0.8 9.8 5.3 0.33 11.0 0.7 2.0 2 0 0 2 2 2 0 YesK-like protein Peptidase_C12 PF01088.16 KFX92196.1 - 5.4e-65 218.5 0.0 6.7e-65 218.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 CH PF00307.26 KFX92196.1 - 0.022 14.8 0.0 0.72 9.9 0.0 2.1 2 0 0 2 2 2 0 Calponin homology (CH) domain MFS_1 PF07690.11 KFX92197.1 - 4.8e-32 111.0 25.7 4.8e-32 111.0 17.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX92197.1 - 2.5e-17 62.6 2.2 2.5e-17 62.6 1.5 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3433 PF11915.3 KFX92197.1 - 0.0011 19.1 3.0 1.7 8.8 0.1 3.7 3 1 0 3 3 3 2 Protein of unknown function (DUF3433) Glyoxalase PF00903.20 KFX92198.1 - 7.4e-10 38.8 2.3 1.6e-09 37.8 1.6 1.6 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KFX92198.1 - 9.5e-06 26.1 1.0 0.029 14.9 0.1 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KFX92198.1 - 0.0052 16.7 0.2 0.037 14.0 0.1 2.3 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Response_reg PF00072.19 KFX92199.1 - 3.5e-13 49.5 0.0 5.1e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain HAD_2 PF13419.1 KFX92201.1 - 5.1e-23 82.1 0.0 5.8e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Consortin_C PF15281.1 KFX92202.1 - 0.53 9.8 3.3 0.94 8.9 2.3 1.5 1 0 0 1 1 1 0 Consortin C-terminus Aldose_epim PF01263.15 KFX92204.1 - 3.9e-60 203.4 0.0 5.2e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DUF3767 PF12597.3 KFX92205.1 - 6.3e-33 112.9 0.3 1.3e-32 111.9 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3767) DUF1744 PF08490.7 KFX92206.1 - 1e-152 508.3 0.0 1.5e-152 507.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) NMT1 PF09084.6 KFX92206.1 - 3.6e-75 252.2 0.0 1.4e-74 250.3 0.0 1.9 2 0 0 2 2 2 1 NMT1/THI5 like DNA_pol_B_exo1 PF03104.14 KFX92206.1 - 1.5e-64 217.9 0.3 2.5e-64 217.1 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 KFX92206.1 - 8.3e-21 74.2 0.1 4.7e-20 71.8 0.2 2.0 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 KFX92206.1 - 1.5e-09 37.7 0.2 4.3e-09 36.2 0.1 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 KFX92206.1 - 1.6e-05 24.8 0.0 5.9e-05 22.9 0.0 2.0 1 0 0 1 1 1 1 RNase_H superfamily NMT1_2 PF13379.1 KFX92206.1 - 0.0023 17.3 0.9 0.74 9.1 0.0 3.4 2 1 0 3 3 3 1 NMT1-like family FtsJ PF01728.14 KFX92207.1 - 1e-10 41.9 0.0 1.8e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 KFX92207.1 - 0.15 12.6 0.0 0.32 11.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Sec62 PF03839.11 KFX92212.1 - 1.8e-50 171.4 0.0 1.8e-50 171.4 0.0 1.5 2 0 0 2 2 2 1 Translocation protein Sec62 APC_CDC26 PF10471.4 KFX92212.1 - 0.022 15.4 6.0 0.082 13.6 0.3 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF2201_N PF13203.1 KFX92212.1 - 0.78 8.8 4.6 0.7 9.0 1.2 1.9 2 0 0 2 2 2 0 Putative metallopeptidase domain BRF1 PF07741.8 KFX92212.1 - 0.9 9.7 5.6 2.5 8.3 0.1 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain DUF2763 PF10961.3 KFX92212.1 - 4.7 7.6 10.7 2.7 8.4 1.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2763) OB_NTP_bind PF07717.11 KFX92223.1 - 1.6e-22 79.4 0.0 3.3e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFX92223.1 - 3e-19 68.9 0.1 7.2e-19 67.7 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFX92223.1 - 2.1e-11 43.4 0.0 4.8e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KFX92223.1 - 1.4e-05 25.2 0.0 3.4e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KFX92223.1 - 0.0012 18.4 0.1 0.0026 17.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 KFX92223.1 - 0.0021 17.9 0.0 2 8.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 KFX92223.1 - 0.026 14.8 0.1 0.089 13.0 0.1 2.0 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 KFX92223.1 - 0.037 13.1 0.0 0.079 12.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin T2SE PF00437.15 KFX92223.1 - 0.057 12.3 0.1 0.22 10.4 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.1 KFX92223.1 - 0.058 12.9 0.1 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KFX92223.1 - 0.12 11.8 0.0 0.34 10.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NmrA PF05368.8 KFX92224.1 - 2.2e-12 46.7 0.0 3.6e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX92224.1 - 2.8e-05 24.2 0.0 7e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KFX92224.1 - 0.012 15.9 0.1 0.079 13.2 0.0 2.3 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain RhgB_N PF09284.5 KFX92229.1 - 1.2e-102 342.5 8.2 1.2e-102 342.5 5.7 1.6 2 0 0 2 2 2 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 KFX92229.1 - 1.2e-60 204.0 0.5 2.2e-59 199.8 0.0 2.3 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 KFX92229.1 - 7.8e-16 57.9 1.0 7.8e-16 57.9 0.7 2.3 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 KFX92229.1 - 0.00022 21.1 1.4 0.00022 21.1 1.0 3.7 5 0 0 5 5 5 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 KFX92229.1 - 0.032 14.0 0.0 0.09 12.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) Pkinase PF00069.20 KFX92230.1 - 3.9e-54 183.5 0.0 4.6e-37 127.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFX92230.1 - 1.9e-22 79.6 0.0 7.4e-21 74.3 0.0 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX92230.1 - 2.3e-05 23.5 0.0 4.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFX92230.1 - 0.00028 20.6 0.0 0.003 17.3 0.0 2.5 3 0 0 3 3 3 1 Phosphotransferase enzyme family MFS_1 PF07690.11 KFX92235.1 - 2e-10 39.9 8.4 2e-10 39.9 5.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2_4 PF13894.1 KFX92236.1 - 0.004 17.3 0.8 0.01 16.1 0.6 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KFX92236.1 - 0.028 14.7 0.6 0.07 13.4 0.4 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type TPR_12 PF13424.1 KFX92237.1 - 1.1e-16 60.5 10.1 3.8e-08 33.1 0.2 3.3 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 KFX92237.1 - 7.9e-08 31.9 2.5 0.13 12.1 0.2 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat zf-C2H2_4 PF13894.1 KFX92237.1 - 3.2e-07 30.1 26.3 0.0086 16.3 0.4 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger TPR_7 PF13176.1 KFX92237.1 - 1.2e-05 24.7 1.8 0.084 12.7 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat zf-C2H2 PF00096.21 KFX92237.1 - 3.1e-05 24.0 33.9 0.011 16.0 1.4 4.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type TPR_1 PF00515.23 KFX92237.1 - 0.00049 19.5 1.0 1.2 8.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFX92237.1 - 0.0033 17.2 1.4 12 6.0 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFX92237.1 - 0.016 14.8 4.5 0.15 11.7 0.4 3.0 1 1 3 4 4 4 0 TPR repeat zf-C2H2_jaz PF12171.3 KFX92237.1 - 0.027 14.5 0.7 0.027 14.5 0.5 4.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding TPR_17 PF13431.1 KFX92237.1 - 0.097 12.9 1.4 27 5.2 0.0 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFX92237.1 - 0.4 10.5 2.1 50 4.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-P11 PF03854.9 KFX92237.1 - 2.8 7.4 10.4 0.064 12.7 1.5 2.5 3 0 0 3 3 3 0 P-11 zinc finger Beta-lactamase PF00144.19 KFX92238.1 - 1.7e-44 152.1 0.0 2e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 KFX92238.1 - 0.0033 16.7 0.0 0.0053 16.0 0.0 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Peptidase_C48 PF02902.14 KFX92240.1 - 6.1e-26 91.3 0.0 1.4e-25 90.2 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF3432 PF11914.3 KFX92241.1 - 0.085 12.8 4.8 0.15 12.1 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) DSPc PF00782.15 KFX92242.1 - 1.3e-28 99.1 0.0 6.5e-20 71.0 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFX92242.1 - 0.00022 20.6 0.0 0.0012 18.2 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DNA_pol_delta_4 PF04081.8 KFX92243.1 - 2.1e-23 82.9 0.6 2.9e-23 82.4 0.4 1.3 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 DUF3484 PF11983.3 KFX92243.1 - 1.7 9.5 4.5 0.59 11.0 1.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) TPR_19 PF14559.1 KFX92244.1 - 5.9e-11 42.5 4.7 1.7e-07 31.5 0.2 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFX92244.1 - 5.4e-06 25.9 5.4 0.12 11.9 0.1 4.7 4 1 1 5 5 5 3 TPR repeat TPR_6 PF13174.1 KFX92244.1 - 4.8e-05 23.5 2.3 0.76 10.3 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFX92244.1 - 6.1e-05 23.3 14.2 0.51 11.1 0.0 5.7 3 1 3 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFX92244.1 - 0.00011 22.7 8.9 0.021 15.4 0.1 4.0 4 1 0 4 4 3 2 Tetratricopeptide repeat Coatomer_E PF04733.9 KFX92244.1 - 0.00029 20.1 0.1 0.00044 19.5 0.1 1.3 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.12 KFX92244.1 - 0.00039 20.1 8.6 2.6 8.1 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 KFX92244.1 - 0.041 14.0 1.4 2.7 8.1 0.0 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KFX92244.1 - 0.063 13.2 6.1 0.38 10.7 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFX92244.1 - 0.23 11.7 2.9 12 6.3 0.1 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFX92244.1 - 0.39 10.5 3.1 34 4.5 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.12 KFX92244.1 - 5.4 7.3 12.8 5.3 7.3 0.1 2.9 4 0 0 4 4 4 0 Bacterial transcriptional activator domain TPR_1 PF00515.23 KFX92244.1 - 7.2 6.3 7.3 14 5.4 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyco_hydro_28 PF00295.12 KFX92245.1 - 7.3e-37 127.0 5.1 4.7e-36 124.3 3.5 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 DUF2672 PF10878.3 KFX92245.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2672) Solute_trans_a PF03619.11 KFX92268.1 - 7e-82 274.8 22.9 8.1e-82 274.6 15.9 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Myb_DNA-bind_6 PF13921.1 KFX92275.1 - 0.0017 18.4 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KFX92275.1 - 0.004 17.2 0.0 0.0064 16.5 0.0 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUP PF00674.13 KFX92275.1 - 0.017 15.0 0.3 0.047 13.6 0.2 1.7 1 1 0 1 1 1 0 DUP family Mitofilin PF09731.4 KFX92280.1 - 0.014 14.0 6.8 0.016 13.8 4.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF605 PF04652.11 KFX92280.1 - 0.14 11.5 32.8 0.19 11.1 22.8 1.1 1 0 0 1 1 1 0 Vta1 like Herpes_BLLF1 PF05109.8 KFX92280.1 - 0.48 8.3 73.7 0.57 8.0 51.1 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) TFIIA PF03153.8 KFX92280.1 - 9.5 5.9 19.6 14 5.4 13.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gtr1_RagA PF04670.7 KFX92281.1 - 1.9e-91 305.3 0.0 3.1e-91 304.6 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region 60KD_IMP PF02096.15 KFX92281.1 - 2e-30 105.9 0.7 3.5e-30 105.1 0.5 1.4 1 0 0 1 1 1 1 60Kd inner membrane protein DUF1275 PF06912.6 KFX92281.1 - 8.2e-27 93.7 5.8 8.2e-27 93.7 4.0 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF1275) Arf PF00025.16 KFX92281.1 - 3.8e-06 26.2 0.0 7e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFX92281.1 - 9.8e-06 25.0 0.0 2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 KFX92281.1 - 6.7e-05 22.8 0.0 0.00027 20.8 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFX92281.1 - 9.3e-05 22.9 0.0 0.00027 21.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 KFX92281.1 - 0.0043 16.5 0.4 0.023 14.2 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.8 KFX92281.1 - 0.023 13.6 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 KFX92281.1 - 0.04 14.2 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 KFX92281.1 - 0.15 11.2 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Borrelia_P83 PF05262.6 KFX92281.1 - 2.7 6.1 8.1 4.6 5.3 5.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein PEP_mutase PF13714.1 KFX92282.1 - 4.6e-45 153.7 0.2 5.8e-45 153.3 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KFX92282.1 - 8.8e-24 83.5 0.5 1.6e-23 82.7 0.3 1.4 1 0 0 1 1 1 1 Isocitrate lyase family TGT PF01702.13 KFX92283.1 - 2.4e-36 125.2 0.0 3.6e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase LCCL PF03815.14 KFX92284.1 - 2.8e-21 75.3 0.2 4.5e-21 74.6 0.1 1.3 1 0 0 1 1 1 1 LCCL domain DUF1688 PF07958.6 KFX92285.1 - 2.2e-179 596.4 0.0 2.5e-179 596.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) RRM_5 PF13893.1 KFX92288.1 - 4.6e-10 39.2 0.0 6.5e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFX92288.1 - 1e-08 34.6 0.0 2.8e-08 33.2 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX92288.1 - 5.1e-07 29.5 0.0 1.1e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 KFX92288.1 - 0.0024 17.4 0.8 0.0034 17.0 0.0 1.7 2 0 0 2 2 2 1 Calcipressin Glyco_hydro_47 PF01532.15 KFX92289.1 - 5.1e-163 542.9 0.0 6.5e-163 542.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GST_N_3 PF13417.1 KFX92291.1 - 1e-14 54.5 0.0 1.7e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KFX92291.1 - 4.5e-13 49.1 0.0 1.3e-11 44.5 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFX92291.1 - 1e-11 44.6 0.0 2.1e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFX92291.1 - 3.1e-08 33.4 0.1 4.9e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFX92291.1 - 2.3e-05 24.2 0.2 3.2e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFX92291.1 - 6.6e-05 23.3 0.2 9.7e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 KFX92291.1 - 0.11 12.8 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 MetRS-N binding domain SMI1_KNR4 PF09346.5 KFX92291.1 - 0.12 12.4 0.2 0.26 11.3 0.1 1.5 1 1 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) GMC_oxred_N PF00732.14 KFX92292.1 - 6.4e-56 189.6 0.0 8.9e-56 189.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFX92292.1 - 2.8e-35 121.7 0.1 5.9e-35 120.6 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KFX92292.1 - 5.4e-09 35.3 0.2 2.3e-07 30.0 0.1 2.5 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.19 KFX92292.1 - 5.5e-06 25.5 0.1 4.2e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFX92292.1 - 0.0003 20.9 0.1 0.11 12.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFX92292.1 - 0.00056 19.8 0.0 0.0015 18.4 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX92292.1 - 0.0015 18.5 0.2 0.0051 16.8 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KFX92292.1 - 0.0023 16.9 0.0 0.0038 16.2 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KFX92292.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding FTA2 PF13095.1 KFX92292.1 - 0.15 11.6 0.0 0.96 9.0 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Peptidase_M3 PF01432.15 KFX92293.1 - 2.9e-118 395.8 0.0 2e-117 393.0 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M91 PF14891.1 KFX92293.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Effector protein Baculo_PEP_C PF04513.7 KFX92293.1 - 0.44 10.3 4.6 1.3 8.8 1.5 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus adh_short PF00106.20 KFX92294.1 - 1.9e-24 86.4 0.1 2.4e-24 86.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX92294.1 - 1e-21 77.8 0.0 1.3e-21 77.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX92294.1 - 4.9e-07 29.5 0.1 7.1e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KFX92294.1 - 4.1e-06 26.1 0.0 0.029 13.5 0.0 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KFX92294.1 - 2.4e-05 24.4 0.3 4.5e-05 23.5 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 KFX92294.1 - 6.6e-05 23.0 0.0 9.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 KFX92294.1 - 0.00011 21.5 0.2 0.00017 20.9 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family ADH_zinc_N PF00107.21 KFX92294.1 - 0.00076 19.0 0.1 0.002 17.6 0.1 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 KFX92294.1 - 0.0023 17.8 0.2 0.0042 17.0 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.14 KFX92294.1 - 0.0031 16.6 0.1 0.0056 15.8 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.16 KFX92294.1 - 0.0068 15.8 0.1 0.024 14.0 0.1 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 KFX92294.1 - 0.026 14.9 0.1 0.053 13.9 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 KFX92294.1 - 0.028 13.8 0.1 0.055 12.9 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KFX92294.1 - 0.034 13.8 0.1 0.067 12.8 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DREV PF05219.7 KFX92294.1 - 0.064 12.1 0.0 0.14 10.9 0.0 1.5 2 0 0 2 2 2 0 DREV methyltransferase DNA_pol_lambd_f PF10391.4 KFX92294.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Fungal_trans PF04082.13 KFX92295.1 - 2.2e-06 26.7 1.9 2.3e-05 23.3 1.2 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX92295.1 - 0.00014 21.6 6.9 0.00023 20.9 4.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KFX92296.1 - 1.5e-102 343.5 19.5 1.8e-102 343.2 13.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX92296.1 - 3.1e-23 82.0 34.0 1e-21 77.0 15.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX92296.1 - 1.9e-07 29.8 17.1 0.00047 18.6 1.3 3.4 3 0 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 KFX92296.1 - 0.00078 17.7 0.5 0.002 16.4 0.3 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TauD PF02668.11 KFX92297.1 - 1.3e-47 162.7 0.1 1.5e-47 162.4 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ADH_N PF08240.7 KFX92298.1 - 1.4e-23 82.7 7.6 3.2e-23 81.5 5.3 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX92298.1 - 1.1e-18 67.0 1.9 1.8e-18 66.3 1.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX92298.1 - 0.00042 21.2 0.3 0.00065 20.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Skp1_POZ PF03931.10 KFX92301.1 - 6.7e-11 42.1 1.4 1.4e-10 41.1 0.5 2.0 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Skp1 PF01466.14 KFX92301.1 - 2.2e-09 37.2 0.3 5e-09 36.0 0.2 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Tox-MPTase3 PF15639.1 KFX92301.1 - 0.0059 16.3 0.8 0.011 15.4 0.6 1.3 1 0 0 1 1 1 1 Metallopeptidase toxin 3 DUF3505 PF12013.3 KFX92302.1 - 0.018 15.2 0.2 0.022 14.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) zf-H2C2_2 PF13465.1 KFX92328.1 - 0.028 14.7 0.6 0.028 14.7 0.4 3.8 4 1 0 4 4 4 0 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFX92328.1 - 0.028 14.7 23.0 1.4 9.4 1.2 4.8 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFX92328.1 - 0.032 14.5 1.2 0.032 14.5 0.8 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF4428 PF14471.1 KFX92328.1 - 0.31 10.8 2.3 0.53 10.0 0.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) zf-CHCC PF10276.4 KFX92328.1 - 1.1 9.1 7.7 5.5 6.9 0.2 3.0 3 0 0 3 3 3 0 Zinc-finger domain Vfa1 PF08432.5 KFX92329.1 - 4.7e-56 189.6 20.4 6e-56 189.3 14.1 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 YABBY PF04690.8 KFX92329.1 - 0.011 15.9 2.6 0.013 15.7 1.8 1.1 1 0 0 1 1 1 0 YABBY protein DUF1510 PF07423.6 KFX92329.1 - 0.023 14.0 21.0 0.03 13.6 14.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MTBP_N PF14918.1 KFX92329.1 - 0.043 13.2 3.6 0.023 14.1 1.1 1.5 1 1 0 1 1 1 0 MDM2-binding SET PF00856.23 KFX92329.1 - 0.057 13.7 1.8 0.063 13.5 1.3 1.3 1 0 0 1 1 1 0 SET domain SIC PF03482.8 KFX92329.1 - 0.077 12.5 3.3 0.16 11.5 2.3 1.6 1 1 0 1 1 1 0 sic protein CDC45 PF02724.9 KFX92329.1 - 0.086 10.8 16.1 0.1 10.6 11.2 1.0 1 0 0 1 1 1 0 CDC45-like protein GAGA_bind PF06217.7 KFX92329.1 - 0.088 12.7 9.8 0.087 12.7 6.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Astro_capsid PF03115.9 KFX92329.1 - 0.09 11.0 6.1 0.11 10.7 4.2 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor BTV_NS2 PF04514.7 KFX92329.1 - 0.096 11.5 13.6 0.11 11.3 9.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DDHD PF02862.12 KFX92329.1 - 0.14 11.9 6.4 0.17 11.6 4.4 1.2 1 0 0 1 1 1 0 DDHD domain Raftlin PF15250.1 KFX92329.1 - 0.17 10.4 7.5 0.2 10.1 5.2 1.1 1 0 0 1 1 1 0 Raftlin NPR3 PF03666.8 KFX92329.1 - 0.18 10.3 8.9 0.21 10.1 6.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tim54 PF11711.3 KFX92329.1 - 0.2 10.2 11.5 0.24 9.9 8.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Borrelia_P83 PF05262.6 KFX92329.1 - 0.26 9.5 22.3 0.3 9.2 15.5 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein U79_P34 PF03064.11 KFX92329.1 - 0.29 10.6 22.4 0.37 10.2 15.5 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FLO_LFY PF01698.11 KFX92329.1 - 0.3 9.8 12.9 0.41 9.4 8.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Peptidase_S49_N PF08496.5 KFX92329.1 - 0.33 10.7 16.3 0.53 10.0 11.3 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ycf1 PF05758.7 KFX92329.1 - 0.41 8.2 14.5 0.44 8.2 10.0 1.0 1 0 0 1 1 1 0 Ycf1 Sec62 PF03839.11 KFX92329.1 - 0.64 9.3 16.9 0.87 8.9 11.7 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 RR_TM4-6 PF06459.7 KFX92329.1 - 0.73 9.6 19.4 0.94 9.3 13.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.17 KFX92329.1 - 1.3 7.9 4.5 1.6 7.6 3.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Ctr PF04145.10 KFX92329.1 - 1.5 8.8 3.1 2.3 8.2 2.2 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Pox_Ag35 PF03286.9 KFX92329.1 - 2.5 7.5 21.9 3.6 7.0 15.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM176 PF14851.1 KFX92329.1 - 2.7 7.6 12.2 4 7.0 8.5 1.4 1 0 0 1 1 1 0 FAM176 family CMV_1a PF12467.3 KFX92329.1 - 3 8.1 16.0 4.3 7.6 11.1 1.2 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family TP53IP5 PF15331.1 KFX92329.1 - 3.4 7.5 12.5 4.2 7.2 8.6 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 GET2 PF08690.5 KFX92329.1 - 3.7 6.6 7.3 4.5 6.4 5.0 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Atrophin-1 PF03154.10 KFX92329.1 - 3.8 5.5 18.6 4.5 5.2 12.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family ATP11 PF06644.6 KFX92329.1 - 3.9 6.8 17.2 4.9 6.5 11.9 1.1 1 0 0 1 1 1 0 ATP11 protein YqfQ PF14181.1 KFX92329.1 - 5.2 7.0 18.6 7.6 6.5 12.9 1.4 1 0 0 1 1 1 0 YqfQ-like protein GCD14 PF08704.5 KFX92329.1 - 5.8 6.3 6.6 7.8 5.9 4.6 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF4246 PF14033.1 KFX92329.1 - 6 5.3 13.5 7.4 5.0 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) RNA_pol_Rpb1_5 PF04998.12 KFX92329.1 - 6.9 5.8 8.3 9.6 5.3 5.8 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF3987 PF13148.1 KFX92329.1 - 7.3 5.0 18.4 9.8 4.6 12.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) RP-C_C PF11800.3 KFX92329.1 - 7.5 6.1 9.8 9.6 5.8 6.8 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region UPF0560 PF10577.4 KFX92329.1 - 8.1 4.5 10.5 8.9 4.4 7.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SAPS PF04499.10 KFX92329.1 - 8.1 4.9 12.1 9.4 4.7 8.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.2 KFX92329.1 - 9.2 3.8 11.6 11 3.5 8.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TRAP_alpha PF03896.11 KFX92329.1 - 9.6 5.1 10.7 13 4.6 7.4 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Rtt106 PF08512.7 KFX92330.1 - 3.4e-25 87.8 0.0 7.7e-25 86.7 0.0 1.6 1 0 0 1 1 1 1 Histone chaperone Rttp106-like CENP-T PF15511.1 KFX92330.1 - 5.4 6.1 14.6 9.4 5.3 10.1 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T GHMP_kinases_N PF00288.21 KFX92331.1 - 7.7e-11 41.8 1.2 2.5e-10 40.2 0.4 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KFX92331.1 - 2.2e-05 24.5 0.0 0.00013 22.0 0.0 2.2 2 0 0 2 2 2 1 GHMP kinases C terminal CRF1 PF10380.4 KFX92341.1 - 0.002 18.4 0.6 0.0057 16.9 0.0 2.2 2 0 0 2 2 2 1 Transcription factor CRF1 Peptidase_S10 PF00450.17 KFX92343.1 - 4.8e-51 174.2 2.2 5.9e-51 173.9 1.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KFX92343.1 - 0.00089 19.1 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX92343.1 - 0.016 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family zf-RING_2 PF13639.1 KFX92344.1 - 1.8e-06 27.6 3.6 1.8e-06 27.6 2.5 1.7 2 0 0 2 2 2 1 Ring finger domain Prok-RING_1 PF14446.1 KFX92344.1 - 0.00073 19.2 1.7 0.00073 19.2 1.2 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 SWIM PF04434.12 KFX92344.1 - 0.0047 16.3 0.1 0.01 15.3 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-Apc11 PF12861.2 KFX92344.1 - 0.0092 15.8 1.7 0.0092 15.8 1.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KFX92344.1 - 0.38 10.8 6.8 0.039 14.0 1.5 1.7 2 0 0 2 2 2 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFX92344.1 - 0.47 10.5 6.1 1.2 9.2 4.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 KFX92344.1 - 1 9.1 6.3 0.5 10.1 1.5 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 KFX92344.1 - 1.1 8.9 5.7 2.4 7.9 3.9 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.1 KFX92344.1 - 1.4 8.7 10.0 0.13 12.0 3.0 2.1 2 0 0 2 2 2 0 zinc-RING finger domain SCRL PF06876.7 KFX92344.1 - 5.2 7.0 9.1 0.82 9.6 1.5 2.4 2 0 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein Tcp11 PF05794.8 KFX92345.1 - 1.1e-52 179.3 0.0 6.8e-52 176.6 0.0 2.0 1 1 0 1 1 1 1 T-complex protein 11 Aa_trans PF01490.13 KFX92346.1 - 2.3e-23 82.3 6.5 3.1e-23 81.9 4.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KFX92346.1 - 0.16 10.7 8.1 0.21 10.3 5.6 1.1 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family HEAT_EZ PF13513.1 KFX92348.1 - 2e-05 24.8 0.2 0.42 11.1 0.0 3.6 3 0 0 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.1 KFX92348.1 - 6.6e-05 23.1 0.6 0.00033 20.8 0.1 2.2 2 1 0 2 2 2 1 HEAT repeats HEAT PF02985.17 KFX92348.1 - 0.00036 20.3 0.0 0.0051 16.7 0.0 2.9 3 0 0 3 3 3 1 HEAT repeat UME PF08064.8 KFX92348.1 - 0.076 12.9 0.0 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 UME (NUC010) domain Actin PF00022.14 KFX92350.1 - 1.3e-158 527.6 0.0 1.4e-158 527.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KFX92350.1 - 0.037 14.4 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF1546 PF07571.8 KFX92351.1 - 9.7e-32 108.9 0.1 8.3e-31 105.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1546) TAF PF02969.12 KFX92351.1 - 2.8e-21 75.2 0.1 6.1e-21 74.1 0.1 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Adaptin_N PF01602.15 KFX92351.1 - 0.026 12.8 1.8 0.028 12.7 0.4 1.5 2 0 0 2 2 2 0 Adaptin N terminal region Histone PF00125.19 KFX92351.1 - 0.039 14.0 0.1 0.094 12.8 0.0 1.7 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Thymidylate_kin PF02223.12 KFX92352.1 - 3e-49 166.9 0.0 3.5e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 KFX92352.1 - 3.2e-07 30.4 0.0 4.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFX92352.1 - 0.00093 19.5 0.4 0.026 14.8 0.0 2.2 1 1 1 2 2 2 1 AAA domain PRK PF00485.13 KFX92352.1 - 0.0015 18.1 0.0 0.004 16.7 0.0 1.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.5 KFX92352.1 - 0.0064 15.7 1.6 0.012 14.8 0.1 2.0 2 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KFX92352.1 - 0.0071 17.1 0.2 0.012 16.3 0.2 1.5 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 KFX92352.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase ThiI PF02568.9 KFX92352.1 - 0.15 11.5 0.1 0.39 10.1 0.1 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) GTP_cyclohydroI PF01227.17 KFX92353.1 - 5.2e-73 244.1 0.1 6.7e-73 243.7 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 KFX92353.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 QueF-like protein EamA PF00892.15 KFX92355.1 - 6e-10 39.2 3.7 1.2e-09 38.2 2.6 1.5 1 0 0 1 1 1 1 EamA-like transporter family Zn_clus PF00172.13 KFX92355.1 - 7.8e-08 32.1 9.0 1.5e-07 31.2 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFX92355.1 - 5.9e-07 28.4 0.3 3.1e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain MIT PF04212.13 KFX92355.1 - 0.014 15.2 0.1 6.1 6.8 0.0 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain E1-E2_ATPase PF00122.15 KFX92355.1 - 0.35 9.8 1.0 0.96 8.4 0.3 1.9 1 1 1 2 2 2 0 E1-E2 ATPase Pox_F17 PF04767.7 KFX92355.1 - 0.78 10.0 2.7 1.7 8.9 1.9 1.5 1 0 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein Aldedh PF00171.17 KFX92356.1 - 1.4e-124 415.9 0.6 1.7e-124 415.6 0.4 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KFX92356.1 - 0.046 12.9 0.0 0.11 11.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) MFS_1 PF07690.11 KFX92357.1 - 1.1e-14 53.9 45.8 1.1e-14 53.9 31.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2244 PF10003.4 KFX92357.1 - 0.036 13.4 0.1 0.036 13.4 0.1 3.6 4 1 0 4 4 4 0 Integral membrane protein (DUF2244) UPF0093 PF03653.8 KFX92357.1 - 0.3 11.0 7.3 0.09 12.7 2.6 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0093) SPC22 PF04573.7 KFX92358.1 - 4.9e-25 87.7 0.0 1.1e-18 67.1 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit IBR PF01485.16 KFX92361.1 - 0.2 11.5 0.1 0.2 11.5 0.1 4.4 3 2 0 3 3 3 0 IBR domain Ribosomal_60s PF00428.14 KFX92361.1 - 0.68 10.3 10.0 2.8 8.4 7.0 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-C3HC4 PF00097.20 KFX92361.1 - 9.3 6.0 32.9 3 7.5 0.8 3.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) PigN PF04987.9 KFX92363.1 - 0.00045 18.9 2.5 0.00045 18.9 1.8 2.3 1 1 2 3 3 3 1 Phosphatidylinositolglycan class N (PIG-N) DUF1524 PF07510.6 KFX92365.1 - 9.1e-14 51.5 0.0 1.1e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.1 KFX92365.1 - 0.06 12.9 0.3 0.18 11.4 0.2 1.7 1 1 0 1 1 1 0 HNH endonuclease Acyl-CoA_dh_1 PF00441.19 KFX92366.1 - 2.6e-25 89.2 0.4 5.2e-25 88.3 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFX92366.1 - 5.4e-17 61.0 0.0 1.4e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain MMR_HSR1 PF01926.18 KFX92366.1 - 6.7e-17 61.5 0.2 3.3e-15 56.0 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Acyl-CoA_dh_2 PF08028.6 KFX92366.1 - 5.2e-14 52.6 0.5 1.5e-13 51.1 0.4 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFX92366.1 - 2.1e-10 41.1 0.0 8.2e-10 39.2 0.0 2.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain FeoB_N PF02421.13 KFX92366.1 - 3.8e-07 29.5 0.2 2.1e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KFX92366.1 - 0.00013 21.2 0.0 0.00026 20.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MTHFR PF02219.12 KFX92366.1 - 0.00019 20.6 0.0 0.24 10.4 0.0 2.3 1 1 1 2 2 2 2 Methylenetetrahydrofolate reductase Dynamin_N PF00350.18 KFX92366.1 - 0.008 16.0 5.9 0.1 12.4 0.1 3.2 3 0 0 3 3 3 1 Dynamin family AIG1 PF04548.11 KFX92366.1 - 0.011 14.8 0.1 0.022 13.8 0.0 1.5 1 0 0 1 1 1 0 AIG1 family Miro PF08477.8 KFX92366.1 - 0.085 13.3 1.4 0.15 12.5 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein Astro_capsid PF03115.9 KFX92366.1 - 0.11 10.7 1.1 0.18 10.0 0.8 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor LTV PF04180.9 KFX92367.1 - 1.1e-94 318.3 15.6 1.3e-94 318.1 10.8 1.0 1 0 0 1 1 1 1 Low temperature viability protein GST_N_3 PF13417.1 KFX92368.1 - 5.1e-06 26.6 0.0 1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFX92368.1 - 6.9e-06 25.9 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KFX92368.1 - 2e-05 24.9 0.0 3.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFX92368.1 - 0.00014 21.6 0.0 0.00043 20.1 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFX92368.1 - 0.0022 17.9 0.0 0.005 16.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DBD_Tnp_Hermes PF10683.4 KFX92368.1 - 0.071 12.5 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain Spo12 PF05032.7 KFX92369.1 - 7.9e-15 54.1 2.2 2.2e-14 52.7 1.2 1.9 2 0 0 2 2 2 1 Spo12 family TGS PF02824.16 KFX92370.1 - 1.2e-20 73.0 0.0 2.9e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KFX92370.1 - 8e-20 70.9 0.1 3.5e-19 68.8 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFX92370.1 - 7.8e-14 51.2 0.0 1.3e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KFX92370.1 - 3.6e-05 23.6 0.4 0.098 12.4 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 KFX92370.1 - 0.0066 16.9 0.0 0.015 15.7 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 KFX92370.1 - 0.052 12.3 0.1 0.12 11.1 0.1 1.6 1 0 0 1 1 1 0 ArgK protein MCM PF00493.18 KFX92370.1 - 0.071 11.8 0.0 0.18 10.5 0.0 1.6 2 0 0 2 2 2 0 MCM2/3/5 family AAA_17 PF13207.1 KFX92370.1 - 0.094 13.5 0.4 0.4 11.5 0.3 2.3 1 1 0 1 1 1 0 AAA domain AIG1 PF04548.11 KFX92370.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 AIG1 family PBS_linker_poly PF00427.16 KFX92370.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide Pro_isomerase PF00160.16 KFX92371.1 - 2.1e-43 148.1 0.6 3.5e-43 147.4 0.4 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.17 KFX92372.1 - 1.9e-22 79.7 0.0 2.3e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 DLH PF01738.13 KFX92374.1 - 1.6e-20 73.3 0.0 2e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFX92374.1 - 8.9e-08 32.0 0.1 1.1e-07 31.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX92374.1 - 0.0005 20.0 1.4 0.23 11.2 0.6 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFX92374.1 - 0.0011 18.2 0.0 0.019 14.1 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 KFX92374.1 - 0.0072 15.7 0.0 0.0096 15.3 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 KFX92374.1 - 0.13 10.7 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) PhyH PF05721.8 KFX92390.1 - 7e-36 124.2 0.0 9.7e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.1 KFX92390.1 - 0.035 14.6 0.5 1.6 9.3 0.1 2.5 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.1 KFX92390.1 - 0.061 13.6 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase F-box PF00646.28 KFX92395.1 - 0.09 12.4 3.9 0.098 12.3 1.1 2.4 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 KFX92395.1 - 0.097 12.4 3.1 0.31 10.7 1.2 2.6 3 0 0 3 3 3 0 F-box-like GATA PF00320.22 KFX92414.1 - 5.5e-17 60.8 2.8 1.9e-16 59.0 1.5 2.2 2 0 0 2 2 2 1 GATA zinc finger DUF1752 PF08550.5 KFX92414.1 - 4.4e-14 51.7 4.6 8.6e-14 50.8 3.2 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Lipase_GDSL_2 PF13472.1 KFX92424.1 - 0.00068 19.8 0.0 0.00096 19.3 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family F-box PF00646.28 KFX92425.1 - 0.0037 16.8 0.0 0.005 16.4 0.0 1.2 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 KFX92425.1 - 0.061 13.2 0.1 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 PRANC domain ERG4_ERG24 PF01222.12 KFX92426.1 - 2.5e-167 556.8 5.9 3e-167 556.5 4.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KFX92426.1 - 0.00032 20.0 0.1 0.00098 18.4 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PhyH PF05721.8 KFX92428.1 - 3.3e-29 102.4 0.1 4.4e-29 102.0 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 KFX92428.1 - 0.00021 21.5 0.1 0.00046 20.4 0.1 1.6 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Zn_clus PF00172.13 KFX92429.1 - 6.7e-09 35.5 9.7 1.1e-08 34.8 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.14 KFX92436.1 - 0.29 11.5 12.0 0.23 11.8 2.9 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein ABA_GPCR PF12430.3 KFX92437.1 - 9.2e-51 171.7 0.0 1.2e-50 171.4 0.0 1.1 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 KFX92437.1 - 8.9e-20 70.5 0.1 3.1e-19 68.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) Pkinase PF00069.20 KFX92439.1 - 3e-66 223.2 0.0 4.6e-66 222.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX92439.1 - 6.2e-52 176.2 0.0 1.1e-51 175.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 KFX92439.1 - 2.3e-29 101.3 0.0 5.1e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 KFX92439.1 - 8.8e-16 57.8 0.1 1.8e-15 56.8 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFX92439.1 - 2.8e-13 49.5 0.1 5.5e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 KFX92439.1 - 1.7e-09 37.9 0.1 3.5e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.1 KFX92439.1 - 2.3e-08 33.3 0.0 3e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 Kinase-like SAM_PNT PF02198.11 KFX92439.1 - 0.0011 18.6 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Kdo PF06293.9 KFX92439.1 - 0.1 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pep3_Vps18 PF05131.9 KFX92441.1 - 5.6e-46 155.6 0.0 1.4e-45 154.2 0.0 1.7 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 KFX92441.1 - 2.4e-07 30.4 2.5 2.5e-05 23.8 0.0 3.6 3 1 1 4 4 4 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 KFX92441.1 - 0.00023 20.9 0.3 0.00058 19.6 0.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFX92441.1 - 0.00064 19.3 0.4 0.0016 18.0 0.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain DUF2175 PF09943.4 KFX92441.1 - 0.11 12.5 0.8 0.41 10.7 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C3HC4_2 PF13923.1 KFX92441.1 - 0.19 11.7 0.4 0.54 10.3 0.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX92441.1 - 0.52 10.0 2.6 0.36 10.5 0.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AIRS_C PF02769.17 KFX92442.1 - 2.9e-33 115.0 0.0 4.6e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 KFX92442.1 - 8.2e-17 61.2 0.8 1.7e-16 60.2 0.5 1.6 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain DHDPS PF00701.17 KFX92443.1 - 1.2e-39 135.6 0.0 1.6e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF218 PF02698.12 KFX92443.1 - 0.11 11.9 0.3 0.35 10.3 0.1 1.8 2 1 0 2 2 2 0 DUF218 domain MR_MLE_C PF13378.1 KFX92444.1 - 6.2e-19 68.0 0.0 3.2e-18 65.7 0.0 2.2 3 0 0 3 3 3 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KFX92444.1 - 2.3e-12 47.2 0.0 6.3e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KFX92444.1 - 0.0021 18.0 0.2 0.0064 16.4 0.0 1.8 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 KFX92444.1 - 0.0023 16.8 0.0 0.0043 16.0 0.0 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus OMPdecase PF00215.19 KFX92445.1 - 1.2e-86 289.8 0.1 1.6e-86 289.3 0.1 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Na_Ca_ex PF01699.19 KFX92446.1 - 1.2e-28 99.4 25.8 5.7e-17 61.6 7.5 3.7 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 KFX92446.1 - 1.2e-14 54.4 13.5 1.2e-14 54.4 9.4 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF307) AAA PF00004.24 KFX92447.1 - 5.4e-44 149.5 0.0 8.5e-44 148.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFX92447.1 - 3.2e-08 33.3 0.0 7.5e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KFX92447.1 - 1.2e-07 31.7 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KFX92447.1 - 2.9e-06 27.4 0.1 6.5e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFX92447.1 - 5.4e-06 26.5 0.1 0.00025 21.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFX92447.1 - 6.9e-05 23.6 0.0 0.00015 22.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFX92447.1 - 7.6e-05 21.8 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KFX92447.1 - 0.00014 21.5 0.1 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KFX92447.1 - 0.00041 19.8 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KFX92447.1 - 0.00087 18.1 0.0 0.0016 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 KFX92447.1 - 0.0014 18.5 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KFX92447.1 - 0.0018 18.1 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFX92447.1 - 0.0024 16.9 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 KFX92447.1 - 0.0025 17.4 0.0 0.0074 15.8 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KFX92447.1 - 0.0039 17.1 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KFX92447.1 - 0.0063 15.6 0.0 0.017 14.2 0.0 1.7 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.16 KFX92447.1 - 0.0068 15.5 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KFX92447.1 - 0.008 16.4 0.0 0.028 14.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 KFX92447.1 - 0.017 14.5 0.1 0.081 12.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KFX92447.1 - 0.018 14.5 0.0 0.085 12.3 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain DUF815 PF05673.8 KFX92447.1 - 0.018 13.9 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.11 KFX92447.1 - 0.021 14.0 0.0 0.07 12.3 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 KFX92447.1 - 0.021 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFX92447.1 - 0.03 14.4 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 KFX92447.1 - 0.049 13.6 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KFX92447.1 - 0.049 12.4 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 KFX92447.1 - 0.079 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2072 PF09845.4 KFX92447.1 - 0.082 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) NACHT PF05729.7 KFX92447.1 - 0.1 12.2 0.0 0.55 9.8 0.0 2.0 1 1 0 2 2 2 0 NACHT domain Y_phosphatase PF00102.22 KFX92448.1 - 2.7e-59 200.3 0.0 4e-58 196.5 0.0 2.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 KFX92448.1 - 1.4e-12 47.9 0.0 4.7e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 KFX92448.1 - 0.05 13.8 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 KFX92448.1 - 0.098 12.2 0.1 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain UCH PF00443.24 KFX92449.1 - 4.5e-21 75.1 0.0 1.2e-20 73.7 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFX92449.1 - 1.9e-14 53.8 0.1 1.8e-13 50.6 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DNA_RNApol_7kD PF03604.8 KFX92449.1 - 0.032 13.7 1.9 1.8 8.1 0.0 2.6 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit CpXC PF14353.1 KFX92449.1 - 0.093 12.7 0.1 1.6 8.6 0.1 2.7 2 1 0 2 2 2 0 CpXC protein Methyltransf_11 PF08241.7 KFX92450.1 - 2.2e-08 34.4 0.0 3.3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX92450.1 - 1.2e-07 31.5 0.0 1.6e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX92450.1 - 4.4e-06 27.0 0.0 7.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX92450.1 - 0.00036 21.0 0.0 0.00063 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX92450.1 - 0.00054 19.5 0.0 0.0007 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX92450.1 - 0.0025 18.1 0.0 0.0041 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KFX92450.1 - 0.11 11.8 0.1 0.16 11.3 0.1 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW CMAS PF02353.15 KFX92450.1 - 0.11 11.5 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Myb_DNA-binding PF00249.26 KFX92451.1 - 3.5e-12 46.1 3.6 5.2e-09 36.0 0.1 2.7 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFX92451.1 - 5.7e-07 29.5 3.8 0.00041 20.3 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain NDUF_B8 PF05821.6 KFX92454.1 - 6.7e-05 22.6 0.0 9.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DUF2205 PF10224.4 KFX92456.1 - 3.4e-31 106.6 3.0 5.9e-31 105.8 2.1 1.4 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) Spectrin PF00435.16 KFX92456.1 - 0.019 15.2 1.3 0.03 14.6 0.9 1.2 1 0 0 1 1 1 0 Spectrin repeat SapC PF07277.6 KFX92456.1 - 0.029 13.6 0.1 0.037 13.3 0.1 1.2 1 0 0 1 1 1 0 SapC Terpene_synth_C PF03936.11 KFX92456.1 - 0.038 13.2 0.1 0.048 12.8 0.1 1.1 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain ApoO PF09769.4 KFX92456.1 - 0.29 10.8 2.2 0.94 9.1 1.5 1.9 1 1 0 1 1 1 0 Apolipoprotein O DUF1510 PF07423.6 KFX92458.1 - 0.00021 20.7 8.4 0.00025 20.5 5.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Neur_chan_memb PF02932.11 KFX92458.1 - 0.034 14.0 2.4 0.04 13.8 1.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ycf1 PF05758.7 KFX92458.1 - 0.048 11.3 7.5 0.052 11.2 5.2 1.1 1 0 0 1 1 1 0 Ycf1 RNA_pol_3_Rpc31 PF11705.3 KFX92458.1 - 0.13 12.1 12.1 0.16 11.8 8.4 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 MIP-T3 PF10243.4 KFX92458.1 - 0.17 10.3 25.9 0.18 10.2 17.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2413 PF10310.4 KFX92458.1 - 0.27 9.9 9.3 0.27 9.9 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Med19 PF10278.4 KFX92458.1 - 0.28 10.8 20.0 0.39 10.3 13.8 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DDHD PF02862.12 KFX92458.1 - 0.35 10.6 7.5 0.42 10.3 5.2 1.2 1 0 0 1 1 1 0 DDHD domain SAPS PF04499.10 KFX92458.1 - 0.38 9.3 4.2 0.4 9.2 2.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4557 PF15101.1 KFX92458.1 - 0.68 9.7 5.6 0.78 9.5 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Pox_Ag35 PF03286.9 KFX92458.1 - 0.71 9.3 16.3 0.89 9.0 11.3 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.9 KFX92458.1 - 0.86 7.5 11.8 1 7.3 8.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 KFX92458.1 - 1 6.9 3.9 1 6.9 2.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Vfa1 PF08432.5 KFX92458.1 - 1.2 9.1 19.6 1.8 8.5 13.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4407 PF14362.1 KFX92458.1 - 1.4 7.8 8.6 1.4 7.7 5.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GAGA_bind PF06217.7 KFX92458.1 - 1.4 8.8 13.1 1.7 8.5 9.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Hex_IIIa PF02455.11 KFX92458.1 - 1.5 7.4 5.7 1.7 7.2 4.0 1.0 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) RR_TM4-6 PF06459.7 KFX92458.1 - 2 8.2 15.1 2.3 8.0 10.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NARP1 PF12569.3 KFX92458.1 - 3.8 6.1 21.0 4.6 5.8 14.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 BTV_NS2 PF04514.7 KFX92458.1 - 4.3 6.1 14.6 5.3 5.8 10.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Sec62 PF03839.11 KFX92458.1 - 4.5 6.6 11.4 5.4 6.3 7.9 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 FLO_LFY PF01698.11 KFX92458.1 - 5.1 5.8 15.2 6.3 5.5 10.5 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Tom37_C PF11801.3 KFX92458.1 - 9.3 6.0 10.2 13 5.6 7.1 1.2 1 0 0 1 1 1 0 Tom37 C-terminal domain Opi1 PF08618.5 KFX92459.1 - 5.9e-81 272.5 16.6 4.6e-69 233.3 3.2 3.7 2 1 1 3 3 3 2 Transcription factor Opi1 Exc PF07825.6 KFX92459.1 - 0.004 16.8 0.6 0.035 13.8 0.0 2.5 2 0 0 2 2 2 1 Excisionase-like protein DUF131 PF01998.12 KFX92460.1 - 0.013 14.8 2.0 0.046 13.0 1.4 1.9 1 0 0 1 1 1 0 Protein of unknown function DUF131 Cys_Met_Meta_PP PF01053.15 KFX92461.1 - 7.2e-55 185.8 0.0 1.6e-53 181.4 0.0 2.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KFX92461.1 - 0.025 13.3 0.0 0.059 12.1 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class-V DUF4131 PF13567.1 KFX92461.1 - 0.16 11.3 0.0 0.99 8.7 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) HATPase_c_3 PF13589.1 KFX92462.1 - 4.7e-15 55.4 0.1 9.3e-15 54.4 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KFX92462.1 - 9.2e-11 41.4 0.1 1.9e-10 40.3 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 KFX92462.1 - 1.2e-10 40.9 0.0 2.6e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain tRNA-synt_1 PF00133.17 KFX92463.1 - 2.2e-217 722.8 1.3 1.1e-216 720.4 0.9 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KFX92463.1 - 7.7e-32 110.1 0.7 1.6e-31 109.0 0.5 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KFX92463.1 - 5.9e-17 61.4 0.4 3.7e-08 32.4 0.0 4.7 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KFX92463.1 - 5.7e-14 51.8 0.5 8.7e-10 38.1 0.0 3.2 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 KFX92463.1 - 0.0018 18.3 5.0 0.0018 18.3 3.5 2.7 2 1 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.14 KFX92463.1 - 0.0037 16.4 0.0 0.028 13.5 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 KFX92463.1 - 0.016 14.0 1.4 0.9 8.2 0.0 3.1 3 0 0 3 3 3 0 tRNA synthetases class I (R) Fusion_gly PF00523.13 KFX92463.1 - 0.073 11.1 0.1 0.12 10.4 0.1 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 Pentaxin PF00354.12 KFX92464.1 - 0.013 14.9 0.2 0.015 14.7 0.2 1.0 1 0 0 1 1 1 0 Pentaxin family Sel1 PF08238.7 KFX92465.1 - 9.1e-35 118.3 36.1 2.5e-06 27.9 0.5 8.6 8 0 0 8 8 8 7 Sel1 repeat zf-RING_2 PF13639.1 KFX92466.1 - 1.2e-09 37.8 9.0 1.7e-08 34.1 2.7 2.4 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.20 KFX92466.1 - 1.6e-05 24.4 2.4 1.6e-05 24.4 1.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFX92466.1 - 0.0026 17.7 9.3 0.0076 16.2 3.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFX92466.1 - 0.0027 17.7 9.9 0.013 15.6 4.7 2.6 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KFX92466.1 - 0.014 15.0 6.5 0.23 11.1 1.6 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 KFX92466.1 - 0.019 14.4 0.3 0.019 14.4 0.2 1.8 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_5 PF14634.1 KFX92466.1 - 0.046 13.4 6.6 0.91 9.3 1.9 2.4 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFX92466.1 - 1.7 8.5 8.7 0.27 11.1 2.1 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFX92466.1 - 5.6 6.7 7.7 0.71 9.6 1.7 2.2 2 0 0 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 KFX92466.1 - 8 6.5 8.0 14 5.7 3.7 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain Pro-kuma_activ PF09286.6 KFX92468.1 - 4.6e-37 127.2 0.2 2e-20 73.3 0.0 2.5 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain PLDc PF00614.17 KFX92470.1 - 1.7e-17 62.5 1.1 2.6e-08 33.3 0.2 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KFX92470.1 - 3.8e-12 46.0 0.1 1.5e-07 31.1 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 KFX92470.1 - 5.9e-07 29.2 0.0 1.7e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 PX domain APH PF01636.18 KFX92471.1 - 0.078 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family F-box PF00646.28 KFX92472.1 - 5.2e-06 25.9 0.9 7.4e-06 25.4 0.0 1.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KFX92472.1 - 0.00015 21.4 0.2 0.00038 20.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like IL5 PF02025.10 KFX92472.1 - 0.12 12.4 0.0 0.76 9.8 0.0 2.2 2 0 0 2 2 2 0 Interleukin 5 F-box-like_2 PF13013.1 KFX92472.1 - 0.12 12.1 0.9 0.24 11.1 0.7 1.5 1 0 0 1 1 1 0 F-box-like domain WD40 PF00400.27 KFX92476.1 - 8.8e-06 25.4 0.1 8.8e-06 25.4 0.1 2.1 2 0 0 2 2 2 1 WD domain, G-beta repeat Daxx PF03344.10 KFX92476.1 - 4.9e-05 22.0 22.6 7.2e-05 21.4 15.6 1.1 1 0 0 1 1 1 1 Daxx Family PI3K_1B_p101 PF10486.4 KFX92476.1 - 0.018 12.6 9.6 0.03 11.9 6.6 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TFIIF_alpha PF05793.7 KFX92476.1 - 0.067 11.5 25.6 0.1 10.9 17.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HEAT_PBS PF03130.11 KFX92476.1 - 0.1 13.1 1.0 15 6.4 0.0 3.6 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Nop14 PF04147.7 KFX92476.1 - 0.13 10.1 22.9 0.2 9.5 15.9 1.2 1 0 0 1 1 1 0 Nop14-like family F-box-like PF12937.2 KFX92476.1 - 0.27 10.9 2.2 0.74 9.5 0.0 2.6 2 1 0 2 2 2 0 F-box-like Sigma70_ner PF04546.8 KFX92476.1 - 1.4 8.4 17.8 3.3 7.2 12.3 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF605 PF04652.11 KFX92476.1 - 3.4 6.9 22.9 5.8 6.2 15.8 1.3 1 0 0 1 1 1 0 Vta1 like BUD22 PF09073.5 KFX92476.1 - 3.8 6.4 34.0 7.2 5.5 23.5 1.3 1 0 0 1 1 1 0 BUD22 Glyco_hydro_18 PF00704.23 KFX92477.1 - 6.5e-80 269.1 2.6 1.1e-79 268.4 1.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KFX92477.1 - 5.5e-09 35.8 12.5 5.5e-09 35.8 8.6 4.1 4 0 0 4 4 4 2 Chitin recognition protein LysM PF01476.15 KFX92478.1 - 4.5e-15 55.2 8.7 2.8e-05 23.9 0.0 6.9 8 0 0 8 8 8 4 LysM domain DLH PF01738.13 KFX92481.1 - 2e-07 30.5 0.5 8.1e-07 28.5 0.3 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 KFX92481.1 - 2.6e-07 30.7 0.0 3e-07 30.5 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KFX92481.1 - 3.4e-07 29.9 0.0 4.2e-07 29.6 0.0 1.0 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.2 KFX92481.1 - 1.7e-06 27.8 0.0 2e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KFX92481.1 - 6.7e-06 25.9 0.0 9e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 KFX92481.1 - 2.6e-05 23.5 0.3 0.00017 20.8 0.1 1.9 1 1 1 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.7 KFX92481.1 - 0.0047 15.4 0.0 0.0079 14.7 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) PAF-AH_p_II PF03403.8 KFX92481.1 - 0.047 11.9 0.2 4.8 5.3 0.0 2.0 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.15 KFX92481.1 - 0.075 12.4 0.0 0.13 11.6 0.0 1.6 1 1 0 1 1 1 0 Putative esterase DUF1100 PF06500.6 KFX92481.1 - 0.16 10.5 0.0 0.16 10.5 0.0 1.0 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Methyltransf_23 PF13489.1 KFX92483.1 - 1.6e-12 47.4 0.4 3.4e-12 46.3 0.3 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX92483.1 - 4.4e-12 46.5 0.0 6.1e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX92483.1 - 2e-11 43.7 0.0 3.2e-11 43.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX92483.1 - 1.3e-10 41.6 0.0 2.2e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX92483.1 - 1.5e-09 38.2 0.0 2.3e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX92483.1 - 2.9e-09 37.1 0.0 7.6e-09 35.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX92483.1 - 1.9e-07 30.4 0.0 1.2e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KFX92483.1 - 6.9e-07 29.3 0.0 1.7e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX92483.1 - 0.0027 17.0 0.0 0.0058 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.6 KFX92483.1 - 0.016 14.6 0.0 0.2 11.0 0.0 2.1 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.1 KFX92483.1 - 0.061 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain BAF1_ABF1 PF04684.8 KFX92483.1 - 0.43 9.3 10.3 0.62 8.8 7.1 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor His_Phos_1 PF00300.17 KFX92484.1 - 2.3e-28 99.2 0.0 2.7e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Tim17 PF02466.14 KFX92488.1 - 3.7e-34 117.5 7.2 4.6e-34 117.2 5.0 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.1 KFX92488.1 - 0.077 12.7 0.0 0.16 11.7 0.0 1.6 1 1 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal DUF2235 PF09994.4 KFX92510.1 - 3.5e-27 95.4 0.0 4.7e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Fungal_trans PF04082.13 KFX92511.1 - 2.6e-17 62.5 0.0 4e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KFX92511.1 - 3.6e-08 33.2 14.4 0.00091 19.4 2.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFX92511.1 - 2.8e-05 24.1 7.1 2.8e-05 24.1 4.9 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFX92511.1 - 0.24 11.8 19.8 0.63 10.5 2.8 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger K_channel_TID PF07941.6 KFX92516.1 - 5.3 7.3 6.4 0.36 11.0 1.2 1.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Pex14_N PF04695.8 KFX92524.1 - 6.3e-39 133.1 0.0 6.3e-39 133.1 0.0 2.6 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3584 PF12128.3 KFX92524.1 - 0.00048 17.6 6.6 0.00063 17.2 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Lebercilin PF15619.1 KFX92524.1 - 0.0041 16.5 5.0 0.0065 15.9 3.5 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease zf-C4H2 PF10146.4 KFX92524.1 - 0.0068 16.4 0.5 0.0068 16.4 0.3 2.0 1 1 1 2 2 2 1 Zinc finger-containing protein WD40_alt PF14077.1 KFX92524.1 - 0.022 14.3 0.4 0.071 12.7 0.1 1.9 1 1 1 2 2 2 0 Alternative WD40 repeat motif CENP-Q PF13094.1 KFX92524.1 - 0.075 13.0 8.8 0.17 11.9 6.1 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Gly_kinase PF02595.10 KFX92524.1 - 0.099 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycerate kinase family IncA PF04156.9 KFX92524.1 - 0.14 11.7 3.4 0.31 10.6 2.3 1.6 1 0 0 1 1 1 0 IncA protein PEP-utilisers_N PF05524.8 KFX92524.1 - 0.23 11.2 5.4 2.7 7.7 1.2 2.9 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal ADIP PF11559.3 KFX92524.1 - 1 9.2 5.9 2 8.2 4.1 1.5 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3829 PF12889.2 KFX92524.1 - 1.4 8.0 5.0 4.7 6.3 2.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) DUF1542 PF07564.6 KFX92524.1 - 1.5 8.8 4.5 0.9 9.6 0.1 2.6 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1542) DUF4164 PF13747.1 KFX92524.1 - 5.3 7.2 14.1 0.67 10.1 5.6 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4164) APG6 PF04111.7 KFX92524.1 - 8.9 5.2 6.5 13 4.7 4.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA PF00004.24 KFX92526.1 - 8.6e-53 178.0 0.0 1.8e-38 131.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KFX92526.1 - 1.3e-11 44.2 0.0 3.1e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 KFX92526.1 - 1.3e-10 40.7 0.4 3.8e-09 36.0 0.1 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 KFX92526.1 - 2.6e-10 40.5 0.3 0.0011 19.1 0.0 4.0 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KFX92526.1 - 7.7e-09 35.5 0.0 0.00072 19.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFX92526.1 - 1.5e-08 34.8 0.0 0.0081 16.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 KFX92526.1 - 4.9e-08 33.8 0.0 0.0085 16.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 KFX92526.1 - 1.8e-07 30.4 0.0 0.006 15.6 0.0 2.9 3 1 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 KFX92526.1 - 2.5e-07 30.8 0.0 0.026 14.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase TIP49 PF06068.8 KFX92526.1 - 3.4e-07 29.3 0.0 0.0095 14.6 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 KFX92526.1 - 3.4e-07 29.9 0.1 0.032 13.9 0.0 2.9 3 0 0 3 3 2 2 Part of AAA domain AAA_5 PF07728.9 KFX92526.1 - 4.4e-07 29.7 0.0 0.0018 18.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KFX92526.1 - 5.9e-07 29.5 0.1 0.00043 20.2 0.1 2.9 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 KFX92526.1 - 1.3e-06 28.6 0.0 0.013 15.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.12 KFX92526.1 - 1.5e-06 27.7 0.6 0.038 13.4 0.0 3.0 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_33 PF13671.1 KFX92526.1 - 5.7e-06 26.2 0.0 0.059 13.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 KFX92526.1 - 1e-05 25.0 0.0 0.076 12.4 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 KFX92526.1 - 1.2e-05 24.4 0.0 0.1 11.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.16 KFX92526.1 - 1.5e-05 24.2 0.1 0.014 14.5 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KFX92526.1 - 3.6e-05 23.4 0.8 0.034 13.8 0.0 3.3 3 1 1 4 4 3 1 NACHT domain ABC_tran PF00005.22 KFX92526.1 - 7.3e-05 23.0 0.1 0.28 11.4 0.1 2.6 2 0 0 2 2 2 2 ABC transporter AAA_25 PF13481.1 KFX92526.1 - 9.6e-05 21.8 0.1 0.5 9.7 0.0 3.3 2 1 1 3 3 3 2 AAA domain AAA_24 PF13479.1 KFX92526.1 - 0.00018 21.1 0.1 0.19 11.2 0.1 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 KFX92526.1 - 0.00022 20.2 0.0 0.68 8.7 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Arch_ATPase PF01637.13 KFX92526.1 - 0.00028 20.6 0.7 5 6.7 0.0 3.6 2 2 2 4 4 4 0 Archaeal ATPase UPF0079 PF02367.12 KFX92526.1 - 0.00045 19.8 0.0 1.2 8.7 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 KFX92526.1 - 0.00054 19.1 0.3 0.024 13.7 0.2 2.3 2 0 0 2 2 2 1 KaiC PhoH PF02562.11 KFX92526.1 - 0.00063 19.0 0.0 1 8.5 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_28 PF13521.1 KFX92526.1 - 0.0022 17.9 0.0 0.69 9.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 KFX92526.1 - 0.0022 17.0 0.0 0.32 9.9 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 KFX92526.1 - 0.0066 16.0 0.0 2.4 7.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 KFX92526.1 - 0.014 15.2 0.2 6.1 6.6 0.0 2.8 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 KFX92526.1 - 0.018 13.9 0.0 0.29 9.9 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 KFX92526.1 - 0.025 14.1 0.0 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 KFX92526.1 - 0.03 13.7 0.1 1.5 8.1 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_11 PF13086.1 KFX92526.1 - 0.041 13.4 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 KFX92526.1 - 0.046 13.7 0.0 7.8 6.5 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_29 PF13555.1 KFX92526.1 - 0.049 13.1 0.1 2.6 7.6 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF815 PF05673.8 KFX92526.1 - 0.071 12.0 0.0 4.3 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) CPT PF07931.7 KFX92526.1 - 0.093 12.3 0.1 2 8.0 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein RasGEF PF00617.14 KFX92527.1 - 4.4e-40 137.4 0.2 6.6e-40 136.8 0.1 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KFX92527.1 - 4.2e-08 33.2 0.1 1.2e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif BDHCT PF08072.6 KFX92528.1 - 0.062 13.4 0.9 5.5 7.1 0.0 2.9 3 0 0 3 3 3 0 BDHCT (NUC031) domain Methyltransf_31 PF13847.1 KFX92529.1 - 2.6e-16 59.5 0.0 8.9e-16 57.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX92529.1 - 3.5e-15 56.5 0.1 1.1e-14 54.9 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX92529.1 - 7.6e-14 51.9 0.2 1.4e-12 47.8 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX92529.1 - 1.1e-13 51.3 0.6 1.1e-12 48.1 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain SET PF00856.23 KFX92529.1 - 9.4e-13 48.7 0.2 6.8e-12 45.9 0.1 2.3 1 1 0 1 1 1 1 SET domain Ubie_methyltran PF01209.13 KFX92529.1 - 2.6e-11 43.0 0.0 5.5e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KFX92529.1 - 1.3e-07 31.6 0.0 3.7e-07 30.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX92529.1 - 4.2e-07 29.5 0.0 8e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KFX92529.1 - 9.9e-07 29.1 0.0 4.7e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 KFX92529.1 - 3.4e-06 26.2 0.0 3.5e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_23 PF13489.1 KFX92529.1 - 9e-06 25.4 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KFX92529.1 - 0.0059 16.2 0.1 0.021 14.4 0.0 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase TehB PF03848.9 KFX92529.1 - 0.022 13.9 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB RRM_1 PF00076.17 KFX92531.1 - 5.6e-10 38.7 2.2 1.3e-09 37.4 0.0 2.6 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX92531.1 - 1.4e-08 34.5 0.2 3e-07 30.3 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX92531.1 - 5.4e-07 29.3 0.1 0.00054 19.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TT_ORF2 PF02957.10 KFX92531.1 - 0.024 15.3 4.8 0.024 15.3 3.4 3.4 3 0 0 3 3 3 0 TT viral ORF2 RNA_pol_Rpc4 PF05132.9 KFX92531.1 - 0.086 12.8 0.1 0.086 12.8 0.1 4.2 3 1 0 3 3 3 0 RNA polymerase III RPC4 TFIIF_alpha PF05793.7 KFX92531.1 - 0.19 10.0 32.0 0.42 8.9 22.2 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sds3 PF08598.6 KFX92532.1 - 3.1e-23 82.4 7.0 3.1e-23 82.4 4.8 3.3 2 2 0 2 2 2 1 Sds3-like Coiled-coil_56 PF09813.4 KFX92533.1 - 5.6e-05 23.0 0.0 6.1e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.3 KFX92534.1 - 3.3e-74 249.2 0.0 6.8e-74 248.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) XPC-binding PF09280.6 KFX92534.1 - 0.047 13.1 0.0 0.8 9.2 0.0 2.7 2 0 0 2 2 2 0 XPC-binding domain Fib_alpha PF08702.5 KFX92535.1 - 8.3 6.5 11.3 4.2 7.4 1.6 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Podoplanin PF05808.6 KFX92535.1 - 9.2 5.8 7.7 0.7 9.4 0.7 2.3 2 1 0 3 3 3 0 Podoplanin A1_Propeptide PF07966.7 KFX92540.1 - 0.019 14.7 1.0 8.5 6.3 0.1 3.5 3 0 0 3 3 3 0 A1 Propeptide Spy1 PF11357.3 KFX92541.1 - 0.13 12.3 0.3 0.2 11.7 0.2 1.2 1 0 0 1 1 1 0 Cell cycle regulatory protein UPF0444 PF15475.1 KFX92543.1 - 0.0073 16.3 1.2 0.019 14.9 0.8 1.7 1 1 0 1 1 1 1 Transmembrane protein C12orf23, UPF0444 Asp PF00026.18 KFX92552.1 - 7.2e-63 212.7 2.9 8.8e-63 212.4 2.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFX92552.1 - 2.5e-06 27.5 0.1 1.9e-05 24.6 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KFX92552.1 - 0.0013 19.2 1.2 0.46 11.0 0.2 3.6 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 KFX92552.1 - 0.024 14.2 0.0 0.16 11.5 0.0 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 KFX92552.1 - 0.052 13.3 1.3 2.8 7.8 0.0 3.1 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Aldedh PF00171.17 KFX92555.1 - 0.2 9.9 1.3 0.23 9.7 0.9 1.0 1 0 0 1 1 1 0 Aldehyde dehydrogenase family NB-ARC PF00931.17 KFX92558.1 - 8.8e-11 41.1 0.0 1.4e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 KFX92558.1 - 0.00044 20.0 0.0 0.0012 18.6 0.0 1.7 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 KFX92558.1 - 0.0013 18.8 0.0 0.0057 16.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFX92558.1 - 0.0022 18.0 0.0 0.0055 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain DAP3 PF10236.4 KFX92558.1 - 0.012 14.6 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NAD_Gly3P_dh_C PF07479.9 KFX92558.1 - 0.085 12.5 0.7 2.5 7.8 0.1 3.1 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus TPP_enzyme_N PF02776.13 KFX92559.1 - 1.1e-35 122.6 0.0 3e-35 121.2 0.0 1.7 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KFX92559.1 - 9.5e-17 60.9 0.0 2.3e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KFX92559.1 - 2.2e-13 50.1 0.0 2.9e-12 46.4 0.0 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Gly_transf_sug PF04488.10 KFX92560.1 - 1.9e-06 28.1 0.0 4.7e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KFX92560.1 - 0.032 12.7 0.0 0.1 11.0 0.0 1.7 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Antimicrobial10 PF08105.6 KFX92560.1 - 0.038 13.6 0.2 0.089 12.4 0.2 1.6 1 0 0 1 1 1 0 Metchnikowin family ABC_membrane PF00664.18 KFX92561.1 - 5.1e-82 275.3 24.6 3e-43 148.2 6.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFX92561.1 - 4.7e-59 198.6 0.0 1.7e-28 99.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFX92561.1 - 4.1e-18 65.4 0.1 7.9e-09 35.0 0.0 4.1 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFX92561.1 - 6e-11 42.8 0.0 0.012 15.5 0.0 4.3 4 0 0 4 4 4 3 AAA domain AAA_22 PF13401.1 KFX92561.1 - 5e-08 33.1 3.4 0.022 14.9 0.1 4.5 3 2 0 3 3 2 2 AAA domain AAA_17 PF13207.1 KFX92561.1 - 8.2e-08 33.1 0.5 0.014 16.1 0.5 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KFX92561.1 - 8.5e-08 31.6 2.1 0.0071 15.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 KFX92561.1 - 3.6e-07 29.7 0.2 0.014 14.7 0.1 2.9 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KFX92561.1 - 8e-07 28.3 0.1 0.014 14.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 KFX92561.1 - 1.5e-06 27.8 7.0 0.14 11.5 0.1 3.7 4 0 0 4 4 3 3 AAA-like domain ABC_ATPase PF09818.4 KFX92561.1 - 1.8e-06 26.8 0.3 0.087 11.3 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 KFX92561.1 - 2.4e-06 27.6 1.9 0.012 15.6 0.3 3.4 3 1 0 3 3 2 2 AAA ATPase domain AAA_18 PF13238.1 KFX92561.1 - 9.3e-06 25.9 0.9 0.27 11.5 0.2 3.1 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 KFX92561.1 - 7.2e-05 22.6 0.2 0.17 11.8 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 KFX92561.1 - 0.00019 21.1 0.8 1.3 8.7 0.0 3.5 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KFX92561.1 - 0.00048 20.0 0.0 0.18 11.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KFX92561.1 - 0.0046 16.4 0.6 2.5 7.5 0.0 2.9 2 1 1 3 3 3 1 FtsK/SpoIIIE family RNA_helicase PF00910.17 KFX92561.1 - 0.0069 16.5 0.3 3.5 7.8 0.0 3.0 3 0 0 3 3 2 1 RNA helicase Zeta_toxin PF06414.7 KFX92561.1 - 0.0092 15.0 0.1 5.1 6.1 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin T2SE PF00437.15 KFX92561.1 - 0.013 14.4 0.3 3 6.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.12 KFX92561.1 - 0.014 14.7 0.9 1.1 8.5 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_23 PF13476.1 KFX92561.1 - 0.023 15.0 3.7 0.1 12.9 0.2 2.3 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KFX92561.1 - 0.03 14.0 1.9 0.36 10.5 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B APS_kinase PF01583.15 KFX92561.1 - 0.038 13.6 0.9 2 8.0 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase ATP-synt_ab PF00006.20 KFX92561.1 - 0.047 13.1 0.7 11 5.3 0.0 2.9 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_13 PF13166.1 KFX92561.1 - 0.054 11.9 2.7 0.63 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KFX92561.1 - 0.056 13.4 2.8 2.3 8.2 0.3 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase PhoH PF02562.11 KFX92561.1 - 0.059 12.6 5.3 2.9 7.0 0.1 3.4 4 0 0 4 4 3 0 PhoH-like protein DUF3987 PF13148.1 KFX92561.1 - 0.063 11.8 0.1 6.2 5.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Mg_chelatase PF01078.16 KFX92561.1 - 0.068 12.3 0.2 0.73 8.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KFX92561.1 - 0.069 12.8 0.2 1.5 8.4 0.0 2.6 2 0 0 2 2 2 0 NACHT domain MTH865 PF07747.6 KFX92561.1 - 0.089 12.4 0.4 10 5.8 0.0 2.4 2 0 0 2 2 2 0 MTH865-like family AAA PF00004.24 KFX92561.1 - 0.091 12.9 0.1 1.7 8.8 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KFX92561.1 - 0.094 12.4 8.0 0.55 10.0 0.3 3.7 4 0 0 4 4 2 0 Part of AAA domain Sigma54_activ_2 PF14532.1 KFX92561.1 - 0.11 12.4 0.0 9.4 6.2 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.1 KFX92561.1 - 0.13 11.7 2.0 0.63 9.5 0.3 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KFX92561.1 - 0.16 11.8 0.0 4.4 7.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 KFX92561.1 - 0.23 11.2 6.7 5 6.8 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 NB-ARC PF00931.17 KFX92561.1 - 0.25 10.1 0.3 2.9 6.6 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Arch_ATPase PF01637.13 KFX92561.1 - 0.76 9.4 1.4 85 2.7 0.0 3.2 3 0 0 3 3 3 0 Archaeal ATPase Polysacc_synt_4 PF04669.8 KFX92562.1 - 1.1e-25 90.1 1.4 5.8e-25 87.7 0.9 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis DUF2491 PF10679.4 KFX92562.1 - 0.015 14.3 0.6 0.017 14.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) Peroxin-22 PF12827.2 KFX92562.1 - 0.091 12.4 0.0 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 Peroxisomal biogenesis protein family ketoacyl-synt PF00109.21 KFX92568.1 - 1.6e-56 191.6 4.9 9.5e-55 185.8 2.2 2.5 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KFX92568.1 - 1.9e-06 27.6 0.2 6.4e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KFX92568.1 - 7.2e-05 21.8 0.4 0.00014 20.9 0.0 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain PPR_2 PF13041.1 KFX92579.1 - 1.1e-52 175.8 1.6 4.7e-09 36.0 0.0 13.4 10 2 4 14 14 14 11 PPR repeat family PPR PF01535.15 KFX92579.1 - 8.8e-26 88.0 17.6 0.0002 21.0 0.0 13.5 15 0 0 15 15 15 5 PPR repeat PPR_1 PF12854.2 KFX92579.1 - 5.8e-25 86.4 0.1 5.8e-08 32.0 0.0 9.5 11 0 0 11 11 11 4 PPR repeat PPR_3 PF13812.1 KFX92579.1 - 2.8e-24 83.2 17.5 0.018 15.3 0.0 14.5 13 1 1 14 14 14 7 Pentatricopeptide repeat domain RPM2 PF08579.6 KFX92579.1 - 7.6e-05 22.8 0.1 0.0036 17.4 0.0 3.7 5 1 0 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_14 PF13428.1 KFX92579.1 - 0.00042 20.6 5.0 1.2 9.9 0.0 7.1 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFX92579.1 - 0.0079 16.5 3.5 0.89 9.9 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat Med9 PF07544.8 KFX92582.1 - 1.3e-18 66.5 0.0 2.2e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.3 KFX92582.1 - 0.035 14.0 8.8 0.11 12.5 6.1 1.9 1 1 0 1 1 1 0 Subunit 21 of Mediator complex Herpes_BLLF1 PF05109.8 KFX92582.1 - 1.7 6.5 12.3 1.8 6.4 8.5 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) iPGM_N PF06415.8 KFX92583.1 - 2.7e-72 242.7 0.0 4.2e-72 242.1 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.13 KFX92583.1 - 3.4e-72 242.8 0.2 3.8e-72 242.6 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 KFX92583.1 - 5.2e-09 35.8 0.1 1.1e-08 34.8 0.0 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KFX92583.1 - 6.1e-08 32.2 0.0 2e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 Sulfatase Alk_phosphatase PF00245.15 KFX92583.1 - 0.051 12.2 0.0 0.086 11.5 0.0 1.3 1 0 0 1 1 1 0 Alkaline phosphatase AP_endonuc_2 PF01261.19 KFX92583.1 - 0.073 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Usp PF00582.21 KFX92586.1 - 3.2e-15 56.5 0.0 7.5e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Universal stress protein family SseC PF04888.7 KFX92586.1 - 0.01 15.1 0.5 0.023 14.0 0.4 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Flu_B_M2 PF04772.7 KFX92586.1 - 0.15 12.0 0.3 0.42 10.6 0.2 1.8 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) Paf67 PF10255.4 KFX92587.1 - 2.1e-154 514.2 0.6 2.5e-154 514.0 0.4 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 KFX92587.1 - 0.035 14.0 2.0 0.13 12.2 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Ku_PK_bind PF08785.6 KFX92589.1 - 1.7e-12 47.2 0.0 3.1e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Ku C terminal domain like Curto_V2 PF07325.6 KFX92589.1 - 0.0057 16.3 0.1 0.0093 15.6 0.0 1.3 1 0 0 1 1 1 1 Curtovirus V2 protein HATPase_c PF02518.21 KFX92606.1 - 3.4e-18 65.3 0.1 1.9e-17 62.9 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KFX92606.1 - 0.00012 21.9 0.0 0.0005 20.0 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 KFX92606.1 - 0.00025 20.7 0.0 0.00049 19.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FAD_binding_4 PF01565.18 KFX92607.1 - 0.018 14.5 0.1 0.071 12.5 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Cu-oxidase_2 PF07731.9 KFX92608.1 - 6.5e-10 38.6 2.8 5.5e-09 35.6 1.9 2.2 1 1 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.17 KFX92608.1 - 0.075 12.9 0.2 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Multicopper oxidase TBP PF00352.16 KFX92615.1 - 7.1e-70 230.4 0.2 4.7e-35 118.8 0.0 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KFX92615.1 - 0.00034 20.6 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) ALO PF04030.9 KFX92619.1 - 2.1e-84 283.1 1.6 3.3e-84 282.5 1.1 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 KFX92619.1 - 1.8e-27 95.5 0.0 2.9e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HC2 PF07382.6 KFX92619.1 - 0.0022 17.8 104.9 0.0059 16.5 44.7 2.2 1 1 1 2 2 2 2 Histone H1-like nucleoprotein HC2 DUF336 PF03928.9 KFX92620.1 - 1e-16 60.9 0.1 1.4e-16 60.5 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF336) DUF3625 PF12293.3 KFX92620.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3625) HEAT PF02985.17 KFX92621.1 - 1.2e-13 49.9 13.2 0.0005 19.9 0.1 9.6 12 0 0 12 12 12 3 HEAT repeat HEAT_2 PF13646.1 KFX92621.1 - 2.6e-12 46.8 12.7 5.7e-05 23.3 0.1 7.2 2 1 5 8 8 8 6 HEAT repeats HEAT_EZ PF13513.1 KFX92621.1 - 2.2e-11 43.8 14.1 2.7e-06 27.7 0.0 8.5 6 3 4 10 10 10 3 HEAT-like repeat CLASP_N PF12348.3 KFX92621.1 - 2e-08 33.8 1.8 0.01 15.2 0.0 5.8 6 2 2 8 8 8 3 CLASP N terminal IBN_N PF03810.14 KFX92621.1 - 2.8e-08 33.5 1.2 1.5e-05 24.8 0.2 3.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.18 KFX92621.1 - 0.00051 19.7 6.4 0.35 10.7 0.0 4.9 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 KFX92621.1 - 0.0048 17.2 1.0 17 6.2 0.0 4.7 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat HMGL-like PF00682.14 KFX92622.1 - 1.9e-63 214.3 0.0 2.8e-63 213.7 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 KFX92622.1 - 2.5e-24 85.5 0.0 4.6e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Zn_clus PF00172.13 KFX92623.1 - 0.0071 16.2 9.0 0.014 15.2 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cleaved_Adhesin PF07675.6 KFX92623.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Cleaved Adhesin Domain Rep_fac-A_C PF08646.5 KFX92623.1 - 0.93 9.1 3.4 1 9.0 1.1 1.8 2 0 0 2 2 2 0 Replication factor-A C terminal domain LSM PF01423.17 KFX92624.1 - 3e-09 36.3 0.0 4.2e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.1 KFX92624.1 - 0.0032 17.8 9.0 0.0065 16.8 6.2 1.5 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 TYW3 PF02676.9 KFX92625.1 - 4.6e-66 221.8 0.0 5.7e-66 221.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 RRM_6 PF14259.1 KFX92626.1 - 1.2e-05 25.2 0.0 2.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ARPC4 PF05856.7 KFX92627.1 - 1.6e-60 203.3 1.1 1.9e-60 203.1 0.8 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.24 KFX92628.1 - 1.2e-53 181.9 0.0 1.5e-53 181.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFX92628.1 - 7.7e-16 58.3 0.0 2.7e-15 56.5 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KFX92628.1 - 1.4e-10 40.4 1.1 2.7e-10 39.5 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin family Coagulase PF08764.5 KFX92628.1 - 0.018 14.9 1.3 0.031 14.2 0.9 1.3 1 0 0 1 1 1 0 Staphylococcus aureus coagulase Pkinase PF00069.20 KFX92632.1 - 9.9e-10 37.9 0.0 1.2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX92632.1 - 0.00097 18.2 0.0 0.0066 15.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase DUF2025 PF09634.5 KFX92634.1 - 0.046 13.4 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2025) AOX PF01786.12 KFX92635.1 - 1.8e-85 285.5 0.0 2.2e-85 285.2 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase PTPLA PF04387.9 KFX92645.1 - 2.8e-37 127.6 2.6 4.9e-37 126.9 1.8 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Pardaxin PF07425.6 KFX92645.1 - 0.061 12.7 1.1 0.31 10.4 0.0 2.5 3 0 0 3 3 3 0 Pardaxin NMO PF03060.10 KFX92664.1 - 1.2e-40 139.7 0.2 1.4e-40 139.4 0.2 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase TMP-TENI PF02581.12 KFX92664.1 - 0.00018 20.6 1.0 0.0006 18.9 0.2 1.9 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI IMPDH PF00478.20 KFX92664.1 - 0.0006 18.8 0.3 0.001 18.0 0.2 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain NanE PF04131.9 KFX92664.1 - 0.0031 16.5 0.1 0.0074 15.2 0.1 1.7 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.13 KFX92664.1 - 0.021 13.6 0.3 0.032 13.0 0.2 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase His_biosynth PF00977.16 KFX92664.1 - 0.038 13.2 0.1 0.085 12.1 0.1 1.6 1 1 0 1 1 1 0 Histidine biosynthesis protein DUF1902 PF08972.6 KFX92664.1 - 0.14 11.7 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) Fungal_trans PF04082.13 KFX92665.1 - 1.1e-23 83.4 0.6 2e-23 82.5 0.3 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain KCNQ_channel PF03520.9 KFX92665.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 KCNQ voltage-gated potassium channel Neisseria_TspB PF05616.8 KFX92680.1 - 4.9 5.4 6.9 6.6 4.9 4.8 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein LAMTOR PF15454.1 KFX92682.1 - 3.3e-16 59.3 0.9 4.8e-16 58.8 0.6 1.2 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Glyco_hydro_45 PF02015.11 KFX92692.1 - 8e-23 81.5 0.6 1.6e-22 80.5 0.4 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Pkinase PF00069.20 KFX92692.1 - 5.4e-06 25.7 0.0 8.9e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain YrbL-PhoP_reg PF10707.4 KFX92692.1 - 5.7e-06 25.8 0.0 9.4e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 KFX92692.1 - 0.00013 21.8 0.2 0.00022 21.0 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KFX92692.1 - 0.00017 20.6 0.0 0.00029 19.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 KFX92692.1 - 0.00026 20.2 0.0 0.00044 19.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) CBM_1 PF00734.13 KFX92692.1 - 0.011 15.4 8.4 0.031 13.9 5.9 1.8 1 0 0 1 1 1 0 Fungal cellulose binding domain Pkinase_Tyr PF07714.12 KFX92692.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase TrkH PF02386.11 KFX92700.1 - 7.2e-120 399.7 18.2 4e-117 390.7 6.7 2.1 2 0 0 2 2 2 2 Cation transport protein Helicase_C_3 PF13625.1 KFX92701.1 - 6.4e-28 97.0 0.0 1e-26 93.1 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX92701.1 - 1.5e-14 54.2 0.0 4.4e-14 52.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KFX92701.1 - 3.8e-12 45.9 0.0 9.1e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KFX92701.1 - 3e-11 42.6 0.1 4.7e-11 42.0 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 KFX92701.1 - 2e-06 27.3 0.0 3.8e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-CHY PF05495.7 KFX92702.1 - 1e-14 54.4 17.8 1.4e-14 54.0 12.4 1.2 1 0 0 1 1 1 1 CHY zinc finger Zn-ribbon_8 PF09723.5 KFX92702.1 - 0.014 15.3 3.9 0.014 15.3 2.7 2.9 3 0 0 3 3 3 0 Zinc ribbon domain Tmemb_55A PF09788.4 KFX92702.1 - 0.026 13.6 5.0 0.031 13.4 3.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A zinc_ribbon_2 PF13240.1 KFX92702.1 - 0.034 13.6 7.5 0.075 12.5 0.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain HypA PF01155.14 KFX92702.1 - 0.044 13.4 1.4 0.044 13.4 1.0 2.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn_Tnp_IS1595 PF12760.2 KFX92702.1 - 0.058 13.2 9.7 3.6 7.4 4.3 2.8 2 1 0 2 2 2 0 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 KFX92702.1 - 0.091 12.5 7.5 4 7.3 0.0 3.3 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-FPG_IleRS PF06827.9 KFX92702.1 - 0.2 11.3 3.9 3.7 7.2 2.9 2.4 1 1 1 2 2 2 0 Zinc finger found in FPG and IleRS LIM PF00412.17 KFX92702.1 - 0.3 11.1 12.8 0.6 10.2 6.9 2.3 1 1 1 2 2 2 0 LIM domain TF_Zn_Ribbon PF08271.7 KFX92702.1 - 0.37 10.1 6.4 1.3 8.3 1.3 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding C1_4 PF07975.7 KFX92702.1 - 0.38 10.7 12.9 0.45 10.5 6.8 2.4 1 1 1 2 2 2 0 TFIIH C1-like domain DZR PF12773.2 KFX92702.1 - 0.62 9.9 10.1 4.1 7.3 7.0 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2 PF00096.21 KFX92702.1 - 0.76 10.2 10.0 1.5 9.2 0.7 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-ribbon_3 PF13248.1 KFX92702.1 - 2 7.7 9.2 2.2 7.5 3.7 2.7 2 1 0 2 2 2 0 zinc-ribbon domain zf-RING_4 PF14570.1 KFX92702.1 - 2.1 8.0 12.4 7.8 6.1 0.1 2.9 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Cytochrome_C7 PF14522.1 KFX92702.1 - 3.7 7.2 12.2 6.2 6.5 8.5 1.4 1 0 0 1 1 1 0 Cytochrome c7 Evr1_Alr PF04777.8 KFX92702.1 - 4.5 7.2 9.1 85 3.1 6.3 2.7 1 1 0 1 1 1 0 Erv1 / Alr family zinc_ribbon_5 PF13719.1 KFX92702.1 - 8.3 6.0 13.9 1.1 8.8 0.2 3.6 3 1 1 4 4 4 0 zinc-ribbon domain Proteasome PF00227.21 KFX92703.1 - 1.2e-54 184.5 0.1 1.6e-54 184.0 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFX92703.1 - 2.5e-13 49.0 0.1 2.5e-13 49.0 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.7 KFX92703.1 - 0.08 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) FAD-oxidase_C PF02913.14 KFX92704.1 - 7.6e-62 208.8 0.0 1.1e-61 208.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KFX92704.1 - 3e-35 120.7 0.5 4.8e-35 120.0 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain adh_short PF00106.20 KFX92708.1 - 1.3e-27 96.7 0.1 1.9e-27 96.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX92708.1 - 2.4e-20 73.3 0.0 3.6e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX92708.1 - 1.3e-11 44.5 0.0 2.1e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFX92708.1 - 1.4e-10 41.5 0.1 2.2e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX92708.1 - 1.8e-05 24.3 0.0 2.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KFX92708.1 - 6.9e-05 22.2 0.2 0.00013 21.3 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 KFX92708.1 - 0.00022 20.2 0.1 0.00037 19.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 KFX92708.1 - 0.0017 18.1 1.1 0.0055 16.4 0.8 2.0 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 KFX92708.1 - 0.0054 15.8 0.0 0.0088 15.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) F420_oxidored PF03807.12 KFX92708.1 - 0.017 15.5 0.1 0.041 14.3 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sulfate_tra_GLY PF13792.1 KFX92708.1 - 2.9 7.6 6.8 2.1 8.0 3.2 1.9 2 0 0 2 2 2 0 Sulfate transporter N-terminal domain with GLY motif MFS_1 PF07690.11 KFX92709.1 - 4.5e-35 121.0 49.6 4.5e-35 121.0 34.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX92709.1 - 1.9e-12 46.5 17.7 1.9e-12 46.5 12.3 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter Lip_prot_lig_C PF10437.4 KFX92709.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus Fungal_trans PF04082.13 KFX92710.1 - 4.7e-18 64.9 0.1 8.4e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX92710.1 - 4.3e-10 39.3 8.0 8.5e-10 38.3 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KFX92711.1 - 6.5e-25 87.9 0.2 8.5e-25 87.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX92711.1 - 1.4e-09 37.9 0.0 1.8e-09 37.5 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFX92711.1 - 4.4e-06 26.6 0.0 5.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 KFX92711.1 - 0.00054 19.7 1.4 0.0012 18.5 1.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KFX92711.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFX92711.1 - 0.06 12.2 0.1 0.078 11.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CS PF04969.11 KFX92712.1 - 3.6e-12 46.6 0.3 5.5e-12 46.0 0.2 1.3 1 0 0 1 1 1 1 CS domain Fork_head_N PF08430.7 KFX92712.1 - 0.17 12.2 13.9 0.28 11.5 9.6 1.3 1 0 0 1 1 1 0 Forkhead N-terminal region Aminotran_5 PF00266.14 KFX92716.1 - 2.4e-08 33.1 0.0 2.7e-07 29.6 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KFX92716.1 - 0.0045 16.0 0.0 0.0081 15.2 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family PYC_OADA PF02436.13 KFX92719.1 - 0.016 14.6 0.2 0.03 13.7 0.1 1.5 1 1 0 1 1 1 0 Conserved carboxylase domain FliT PF05400.8 KFX92719.1 - 0.77 10.2 3.9 4.5 7.7 0.2 2.9 2 1 1 3 3 3 0 Flagellar protein FliT LTXXQ PF07813.7 KFX92719.1 - 2.4 8.6 6.8 0.92 10.0 0.5 2.6 2 1 0 2 2 2 0 LTXXQ motif family protein Glutaredoxin PF00462.19 KFX92720.1 - 1.8e-13 50.2 0.0 2.6e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin RNase_PH_C PF03725.10 KFX92740.1 - 1.5e-08 34.4 0.0 2.4e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RNase_PH PF01138.16 KFX92740.1 - 7.3e-07 29.5 0.5 1.3e-06 28.7 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNA12 PF10443.4 KFX92740.1 - 0.12 10.8 0.2 0.14 10.6 0.1 1.1 1 0 0 1 1 1 0 RNA12 protein HEAT PF02985.17 KFX92741.1 - 9.4e-08 31.5 0.3 0.22 11.7 0.0 5.1 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 KFX92741.1 - 6.2e-06 26.3 6.5 0.0048 17.1 1.3 5.0 3 1 1 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 KFX92741.1 - 0.094 13.2 0.1 0.094 13.2 0.0 5.1 7 0 0 7 7 7 0 HEAT-like repeat Nop14 PF04147.7 KFX92741.1 - 2.4 5.9 14.6 4.7 5.0 10.1 1.4 1 0 0 1 1 1 0 Nop14-like family Iso_dh PF00180.15 KFX92746.1 - 1.1e-83 281.1 0.0 1.4e-83 280.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Proteasome PF00227.21 KFX92747.1 - 1.4e-45 154.9 0.1 1.7e-31 109.0 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 KFX92747.1 - 3.8e-11 42.0 1.2 3.9e-11 42.0 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Trs65 PF12735.2 KFX92750.1 - 1.2e-37 129.9 0.2 1e-36 126.8 0.0 2.0 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 FF PF01846.14 KFX92751.1 - 1.3e-51 172.2 14.0 6.4e-15 54.8 0.4 6.7 6 0 0 6 6 6 5 FF domain WW PF00397.21 KFX92751.1 - 4.8e-19 67.8 10.3 7.2e-11 41.7 0.8 2.6 2 0 0 2 2 2 2 WW domain ABC_tran PF00005.22 KFX92752.1 - 1.5e-33 115.9 0.0 2.3e-15 57.0 0.0 2.6 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 KFX92752.1 - 4.5e-14 51.7 5.2 4.5e-14 51.7 3.6 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 KFX92752.1 - 5.7e-13 49.4 7.9 0.0088 16.0 0.8 4.7 3 2 0 3 3 3 2 AAA domain SMC_N PF02463.14 KFX92752.1 - 7.1e-11 41.7 2.3 0.0014 17.8 0.0 3.6 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KFX92752.1 - 8.8e-07 28.3 0.2 2.3 7.1 0.0 4.5 4 1 0 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 KFX92752.1 - 7e-06 26.8 0.0 0.2 12.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 KFX92752.1 - 4.1e-05 23.7 0.1 0.04 14.1 0.0 2.7 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Fer4 PF00037.22 KFX92752.1 - 5.6e-05 22.5 3.2 5.6e-05 22.5 2.2 2.8 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_29 PF13555.1 KFX92752.1 - 7.1e-05 22.2 0.1 0.065 12.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KFX92752.1 - 8.4e-05 22.7 0.0 0.023 14.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFX92752.1 - 0.00016 22.0 0.1 0.36 11.1 0.0 3.0 4 0 0 4 4 2 1 AAA domain DUF258 PF03193.11 KFX92752.1 - 0.00022 20.4 2.4 0.55 9.4 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KFX92752.1 - 0.00045 20.5 0.0 0.035 14.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.1 KFX92752.1 - 0.00091 19.0 11.8 0.0022 17.8 8.2 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain VirE PF05272.6 KFX92752.1 - 0.00092 18.7 0.1 1.6 8.1 0.0 2.6 2 0 0 2 2 2 2 Virulence-associated protein E AAA_25 PF13481.1 KFX92752.1 - 0.00099 18.5 0.1 0.63 9.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 KFX92752.1 - 0.0019 17.7 0.2 0.028 14.0 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 KFX92752.1 - 0.002 18.6 0.2 0.21 12.0 0.0 3.0 3 0 0 3 3 3 1 Miro-like protein RNA_helicase PF00910.17 KFX92752.1 - 0.002 18.2 1.0 0.56 10.3 0.0 2.8 3 0 0 3 3 2 1 RNA helicase MobB PF03205.9 KFX92752.1 - 0.0021 17.7 1.8 0.2 11.3 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KFX92752.1 - 0.0025 17.6 0.2 0.13 12.0 0.1 2.5 2 0 0 2 2 2 1 AAA domain Fer4_6 PF12837.2 KFX92752.1 - 0.003 17.3 11.8 0.0068 16.2 1.4 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain NACHT PF05729.7 KFX92752.1 - 0.0034 17.0 2.0 0.26 10.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Rad17 PF03215.10 KFX92752.1 - 0.0047 15.6 0.1 0.068 11.8 0.0 2.5 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_13 PF13166.1 KFX92752.1 - 0.011 14.2 0.0 0.011 14.2 0.0 2.0 3 0 0 3 3 1 0 AAA domain Thymidylate_kin PF02223.12 KFX92752.1 - 0.011 15.0 2.4 7.7 5.8 0.0 3.3 3 0 0 3 3 3 0 Thymidylate kinase SRP54 PF00448.17 KFX92752.1 - 0.017 14.5 5.0 0.099 12.0 0.3 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Fer4_7 PF12838.2 KFX92752.1 - 0.029 14.7 1.7 0.029 14.7 1.2 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.1 KFX92752.1 - 0.044 14.5 0.1 0.044 14.5 0.1 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_16 PF13191.1 KFX92752.1 - 0.047 13.6 0.0 9.4 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.17 KFX92752.1 - 0.065 12.0 0.1 4.2 6.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.9 KFX92752.1 - 0.066 12.9 0.3 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KFX92752.1 - 0.076 12.9 0.4 4.9 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KFX92752.1 - 0.098 12.2 0.2 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KFX92752.1 - 0.12 12.3 0.0 9.2 6.2 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit KaiC PF06745.8 KFX92752.1 - 0.13 11.4 0.1 0.3 10.1 0.1 1.6 1 0 0 1 1 1 0 KaiC PduV-EutP PF10662.4 KFX92752.1 - 0.16 11.4 0.2 0.16 11.4 0.1 2.4 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Fer4_10 PF13237.1 KFX92752.1 - 0.24 11.2 15.7 0.031 14.0 1.3 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_14 PF13173.1 KFX92752.1 - 0.31 10.9 1.6 25 4.7 0.0 3.1 2 2 1 3 3 2 0 AAA domain AAA_24 PF13479.1 KFX92752.1 - 0.36 10.3 3.9 0.83 9.1 0.1 2.6 3 0 0 3 3 2 0 AAA domain Fer4_8 PF13183.1 KFX92752.1 - 0.43 10.6 9.3 0.31 11.0 1.1 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 KFX92752.1 - 0.55 10.2 12.9 0.61 10.1 1.9 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain NTPase_1 PF03266.10 KFX92752.1 - 0.83 9.3 2.9 18 4.9 0.1 2.6 2 0 0 2 2 2 0 NTPase Fer4_9 PF13187.1 KFX92752.1 - 1.4 9.2 14.3 0.035 14.3 1.5 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain SNF2_N PF00176.18 KFX92753.1 - 1.1e-63 214.8 0.0 1.7e-63 214.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 KFX92753.1 - 3e-23 81.2 1.6 2.9e-12 46.0 0.1 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KFX92753.1 - 1e-13 50.9 0.0 3.3e-13 49.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4208 PF13907.1 KFX92753.1 - 3e-10 40.2 0.0 1.6e-09 37.8 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Fungal_trans_2 PF11951.3 KFX92754.1 - 5.8e-08 31.7 1.0 5.8e-08 31.7 0.7 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain RTA1 PF04479.8 KFX92755.1 - 4.8e-57 193.0 9.1 6.1e-57 192.7 6.3 1.1 1 0 0 1 1 1 1 RTA1 like protein GST_N_3 PF13417.1 KFX92758.1 - 1.5e-10 41.1 0.1 3.1e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFX92758.1 - 2.5e-06 27.3 0.0 5.5e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain IBN_N PF03810.14 KFX92758.1 - 0.058 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Importin-beta N-terminal domain Kp4 PF09044.5 KFX92759.1 - 4.8e-29 100.7 2.2 5.8e-29 100.5 1.6 1.1 1 0 0 1 1 1 1 Kp4 MU117 PF15474.1 KFX92759.1 - 0.022 15.2 1.5 0.029 14.8 1.0 1.3 1 0 0 1 1 1 0 Meiotically up-regulated gene family ELO PF01151.13 KFX92760.1 - 2.1e-63 213.9 20.7 2.5e-63 213.7 14.4 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF1947 PF09183.5 KFX92760.1 - 0.18 11.5 2.4 2.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) Ribosomal_L4 PF00573.17 KFX92761.1 - 3.3e-39 134.2 0.4 4.7e-39 133.7 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 KFX92761.1 - 2.1e-27 94.7 1.5 3.1e-27 94.2 0.2 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain HDA2-3 PF11496.3 KFX92762.1 - 2.3e-15 56.2 0.0 5.8e-14 51.5 0.0 2.3 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AT_hook PF02178.14 KFX92762.1 - 2.6 8.0 26.5 0.043 13.4 2.1 3.6 3 0 0 3 3 3 0 AT hook motif COX5A PF02284.11 KFX92763.1 - 4.3e-41 139.2 0.6 5.7e-41 138.8 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DHC_N1 PF08385.7 KFX92763.1 - 0.022 13.1 0.3 0.19 10.0 0.0 1.9 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 1 DUF1804 PF08822.6 KFX92763.1 - 0.069 12.8 0.0 0.086 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) PgaD PF13994.1 KFX92769.1 - 0.13 11.7 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 PgaD-like protein Clr5 PF14420.1 KFX92770.1 - 8.5e-18 63.9 4.3 1.6e-17 63.0 3.0 1.4 1 0 0 1 1 1 1 Clr5 domain Stn1 PF10451.4 KFX92770.1 - 0.035 12.9 1.5 0.042 12.6 0.8 1.3 1 1 0 1 1 1 0 Telomere regulation protein Stn1 DUF632 PF04782.7 KFX92770.1 - 0.045 12.8 6.0 0.053 12.6 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF632) Prefoldin_3 PF13758.1 KFX92770.1 - 0.14 11.9 4.2 0.29 10.9 2.4 1.8 1 1 1 2 2 2 0 Prefoldin subunit TMF_TATA_bd PF12325.3 KFX92770.1 - 0.31 10.7 3.0 0.25 11.1 1.1 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Ank_2 PF12796.2 KFX92771.1 - 7.7e-154 500.5 40.8 2e-21 76.1 0.1 10.6 2 1 9 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.25 KFX92771.1 - 3.1e-106 342.2 48.0 1.1e-06 28.1 0.1 22.5 23 0 0 23 23 23 19 Ankyrin repeat Ank_3 PF13606.1 KFX92771.1 - 6.9e-89 282.7 20.5 1e-05 25.2 0.0 21.6 22 0 0 22 22 22 18 Ankyrin repeat Ank_4 PF13637.1 KFX92771.1 - 1e-78 258.4 15.7 2.4e-09 37.4 0.0 16.9 9 3 8 17 17 17 16 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX92771.1 - 1.3e-59 196.8 30.5 2.2e-07 30.8 0.3 17.8 7 5 12 19 19 19 14 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 KFX92771.1 - 1.7e-05 24.4 2.8 20 4.5 0.0 7.8 6 2 4 10 10 10 1 Shigella flexneri OspC protein DUF484 PF04340.7 KFX92771.1 - 0.13 11.7 1.3 9.2 5.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF484 DUF737 PF05300.6 KFX92773.1 - 0.039 13.9 2.6 0.045 13.7 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) COesterase PF00135.23 KFX92774.1 - 6.4e-60 203.3 0.0 9.4e-60 202.8 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX92774.1 - 0.00015 21.4 0.2 0.0015 18.1 0.1 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFX92774.1 - 0.0035 16.5 0.0 0.0054 15.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Glyco_hydro_61 PF03443.9 KFX92782.1 - 4.7e-61 206.3 0.0 6.8e-61 205.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Coatomer_E PF04733.9 KFX92784.1 - 4.1e-63 213.2 8.9 5.4e-63 212.8 6.2 1.1 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 KFX92784.1 - 5.1e-11 42.7 25.5 2.8e-05 24.3 0.4 4.7 2 2 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFX92784.1 - 1.3e-08 34.6 20.5 3.3e-06 27.2 0.3 5.8 3 1 3 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFX92784.1 - 2.6e-08 34.3 19.3 0.00029 21.4 0.0 4.9 3 1 3 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFX92784.1 - 6.5e-08 32.1 7.8 4e-07 29.5 0.0 3.7 3 1 1 4 4 4 1 TPR repeat TPR_6 PF13174.1 KFX92784.1 - 1.1e-05 25.4 6.1 0.0051 17.1 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat Apc3 PF12895.2 KFX92784.1 - 2.6e-05 24.2 5.3 0.017 15.2 0.2 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KFX92784.1 - 8.1e-05 22.0 0.9 0.0079 15.7 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFX92784.1 - 0.0013 18.4 0.0 0.0013 18.4 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFX92784.1 - 0.0074 16.2 10.7 0.3 11.0 0.0 4.3 1 1 3 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFX92784.1 - 0.0092 16.1 4.4 0.068 13.3 0.0 4.0 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 KFX92784.1 - 0.016 15.5 15.2 0.76 10.3 0.2 5.6 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFX92784.1 - 0.022 14.5 3.6 3 7.8 0.0 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 KFX92784.1 - 0.4 10.6 21.4 0.15 11.9 0.4 3.3 1 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 KFX92784.1 - 2.1 8.2 6.0 5.2 6.9 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat HAD PF12710.2 KFX92785.1 - 3.3e-12 46.9 0.0 4.8e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 KFX92785.1 - 0.0029 16.8 0.0 0.04 13.0 0.0 2.3 2 1 0 2 2 2 1 Putative Phosphatase Herpes_US12 PF05363.7 KFX92785.1 - 0.029 14.8 0.1 11 6.6 0.0 3.0 3 0 0 3 3 3 0 Herpesvirus US12 family UMPH-1 PF05822.7 KFX92785.1 - 0.034 13.4 0.0 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.21 KFX92785.1 - 0.037 14.4 0.1 0.33 11.3 0.1 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Lipase_GDSL_2 PF13472.1 KFX92786.1 - 1.9e-10 41.1 0.0 3.8e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF2305 PF10230.4 KFX92789.1 - 2.8e-46 158.0 0.0 3.9e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 KFX92789.1 - 9.1e-08 32.2 0.3 2.4e-07 30.8 0.2 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX92789.1 - 0.02 14.6 0.0 0.064 13.0 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF1057 PF06342.7 KFX92789.1 - 0.58 8.9 0.0 1.4 7.7 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Peptidase_M28 PF04389.12 KFX92790.1 - 5.2e-23 81.6 0.0 1.4e-22 80.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KFX92790.1 - 4.5e-16 58.3 0.0 8.5e-16 57.4 0.0 1.5 1 0 0 1 1 1 1 PA domain Kp4 PF09044.5 KFX92791.1 - 6.4e-45 152.0 15.4 6.2e-23 80.9 1.7 2.0 2 0 0 2 2 2 2 Kp4 MU117 PF15474.1 KFX92791.1 - 0.0097 16.3 9.6 0.14 12.6 1.4 2.5 2 1 0 2 2 2 2 Meiotically up-regulated gene family Beta-TrCP_D PF12125.3 KFX92791.1 - 0.041 13.4 0.1 2.1 7.9 0.0 2.4 2 0 0 2 2 2 0 D domain of beta-TrCP FYVE PF01363.16 KFX92791.1 - 0.068 13.0 0.1 3.3 7.6 0.0 2.4 2 0 0 2 2 2 0 FYVE zinc finger zf-ribbon_3 PF13248.1 KFX92791.1 - 1.2 8.4 5.3 5.5 6.3 0.4 2.5 2 0 0 2 2 2 0 zinc-ribbon domain AIG2 PF06094.7 KFX92792.1 - 1.3e-06 28.8 0.0 1.7e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 AIG2-like family DUF972 PF06156.8 KFX92793.1 - 0.022 15.0 1.0 1.1 9.6 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) CENP-Q PF13094.1 KFX92793.1 - 0.035 14.1 3.9 0.041 13.8 1.5 1.9 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF310 PF03750.8 KFX92793.1 - 0.08 13.1 0.2 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF310) Seryl_tRNA_N PF02403.17 KFX92793.1 - 0.14 12.2 1.0 1 9.4 0.3 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DivIC PF04977.10 KFX92793.1 - 1.3 8.5 3.1 13 5.3 0.0 2.3 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 KFX92793.1 - 1.6 8.3 4.5 0.55 9.7 0.4 2.1 3 0 0 3 3 3 0 IncA protein Rubella_Capsid PF05750.6 KFX92794.1 - 0.31 10.3 4.8 0.34 10.2 3.3 1.0 1 0 0 1 1 1 0 Rubella capsid protein DUF1275 PF06912.6 KFX92797.1 - 0.00045 19.4 0.9 0.00045 19.4 0.6 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1275) MTP18 PF10558.4 KFX92797.1 - 0.081 12.7 0.3 0.26 11.1 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial 18 KDa protein (MTP18) Transp_cyt_pur PF02133.10 KFX92799.1 - 4.1e-142 473.8 34.3 4.7e-142 473.6 23.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SurE PF01975.12 KFX92800.1 - 4.6e-39 133.7 0.0 6.4e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Survival protein SurE Aldedh PF00171.17 KFX92801.1 - 8.5e-117 390.3 1.9 8.4e-114 380.4 0.3 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family MFS_1 PF07690.11 KFX92801.1 - 9.5e-16 57.4 45.8 9.5e-16 57.4 31.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily UPF0093 PF03653.8 KFX92801.1 - 0.043 13.7 5.3 0.11 12.5 3.7 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0093) DUF1212 PF06738.7 KFX92806.1 - 1.7e-58 197.3 5.6 2.3e-53 180.5 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KFX92806.1 - 5.9e-32 110.3 7.5 5.9e-32 110.3 5.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) Aldedh PF00171.17 KFX92807.1 - 2.1e-160 534.0 0.3 2.4e-160 533.8 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.14 KFX92808.1 - 7.2e-50 169.8 0.0 1e-49 169.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFX92808.1 - 1.3e-37 129.2 0.0 2.1e-37 128.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KFX92808.1 - 1.8e-06 27.1 0.0 0.0008 18.4 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX92808.1 - 0.00015 21.7 0.1 0.0011 18.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFX92808.1 - 0.00028 19.8 0.0 0.096 11.5 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KFX92808.1 - 0.0009 18.2 0.0 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KFX92808.1 - 0.015 15.1 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KFX92808.1 - 0.017 14.1 0.0 0.49 9.4 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFX92808.1 - 0.066 13.6 0.1 1.8 9.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KFX92808.1 - 0.11 11.0 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase adh_short_C2 PF13561.1 KFX92809.1 - 3.8e-19 69.4 0.1 2.5e-18 66.7 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFX92809.1 - 2.5e-18 66.5 3.3 7.3e-18 65.0 2.3 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX92809.1 - 2.5e-10 40.3 0.4 4.4e-10 39.5 0.3 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KFX92809.1 - 0.0015 17.7 0.0 0.0025 17.0 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_7 PF13241.1 KFX92809.1 - 0.002 18.3 0.0 0.0044 17.2 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Polysacc_synt_2 PF02719.10 KFX92809.1 - 0.017 14.0 0.1 0.022 13.6 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.21 KFX92809.1 - 0.023 14.2 0.4 0.055 13.0 0.3 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase HTHP PF11534.3 KFX92809.1 - 0.026 14.5 0.1 0.19 11.8 0.0 2.2 2 0 0 2 2 2 0 Hexameric tyrosine-coordinated heme protein (HTHP) FAD_binding_3 PF01494.14 KFX92809.1 - 0.1 11.6 0.3 0.16 11.0 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 KFX92809.1 - 0.13 12.7 0.3 0.44 10.9 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 KFX92816.1 - 1.5e-08 33.8 0.2 2.3e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX92816.1 - 1.9e-06 27.6 10.0 3.9e-06 26.6 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Xpo1 PF08389.7 KFX92817.1 - 2.1e-28 99.1 1.1 2.1e-28 99.1 0.8 2.9 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 KFX92817.1 - 1.2e-06 28.3 0.1 1.3e-05 24.9 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Sec7_N PF12783.2 KFX92817.1 - 0.015 14.7 0.0 0.05 13.0 0.0 1.9 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Adaptin_N PF01602.15 KFX92817.1 - 0.067 11.4 0.7 5.6 5.1 0.1 2.4 2 0 0 2 2 2 0 Adaptin N terminal region TIM21 PF08294.6 KFX92818.1 - 3e-40 137.2 0.0 3.7e-40 136.9 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 KFX92818.1 - 7.9e-07 28.5 0.0 1.8e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Sec39 PF08314.6 KFX92848.1 - 7.2e-18 63.9 0.6 8.4e-18 63.6 0.4 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Fungal_trans_2 PF11951.3 KFX92854.1 - 9.2e-25 87.0 4.1 4.8e-24 84.6 2.9 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX92854.1 - 2.7e-07 30.3 6.7 6e-07 29.2 4.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3505 PF12013.3 KFX92855.1 - 3.4e-06 27.2 0.6 1.4e-05 25.2 0.3 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3505) zf-C2H2_2 PF12756.2 KFX92855.1 - 0.028 14.5 0.4 2.4 8.3 0.0 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 KFX92855.1 - 0.26 11.4 3.7 1.2 9.3 0.8 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding AMP-binding PF00501.23 KFX92862.1 - 6.8e-93 311.3 0.6 8.3e-93 311.0 0.4 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX92862.1 - 1.8e-21 76.8 0.3 1.1e-19 71.1 0.1 2.8 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Zn_clus PF00172.13 KFX92868.1 - 9.6e-07 28.6 8.5 1.9e-06 27.6 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_5 PF00266.14 KFX92869.1 - 2e-29 102.4 0.0 2.4e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V GTP1_OBG PF01018.17 KFX92887.1 - 4.4e-36 123.8 5.6 3.5e-27 94.9 3.0 2.4 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 KFX92887.1 - 2.1e-21 76.0 0.0 3.5e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFX92887.1 - 2.2e-07 30.2 0.1 5e-07 29.1 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 KFX92887.1 - 0.065 11.9 0.0 0.38 9.4 0.0 2.0 2 0 0 2 2 2 0 ArgK protein GTP_EFTU PF00009.22 KFX92887.1 - 0.14 11.5 0.0 3.3 7.1 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KFX92887.1 - 0.15 12.3 1.1 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter CENP-F_leu_zip PF10473.4 KFX92889.1 - 0.00089 19.1 13.4 0.00089 19.1 9.3 3.9 3 2 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Propeptide_C1 PF08127.8 KFX92889.1 - 0.017 14.6 0.3 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 Peptidase family C1 propeptide DEAD PF00270.24 KFX92890.1 - 5.4e-41 139.9 0.1 9.9e-41 139.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase RNA_pol_Rpb5_C PF01191.14 KFX92890.1 - 1.3e-32 111.2 0.3 3.7e-32 109.7 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KFX92890.1 - 5.7e-28 97.1 0.0 1.2e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Helicase_C PF00271.26 KFX92890.1 - 1e-21 76.5 0.4 4e-21 74.6 0.3 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KFX92890.1 - 0.0049 15.6 0.0 0.008 15.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KFX92890.1 - 0.013 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 KFX92890.1 - 0.039 13.2 0.1 0.34 10.1 0.0 2.3 3 0 0 3 3 3 0 SecA DEAD-like domain Mrr_cat PF04471.7 KFX92890.1 - 0.045 13.5 0.0 0.18 11.6 0.0 2.0 1 0 0 1 1 1 0 Restriction endonuclease WD40 PF00400.27 KFX92891.1 - 2.4e-25 87.4 22.5 2.1e-08 33.6 0.0 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat BTB PF00651.26 KFX92891.1 - 2.1e-17 63.0 0.3 2.7e-07 30.5 0.0 2.9 3 0 0 3 3 3 2 BTB/POZ domain Cation_efflux PF01545.16 KFX92902.1 - 2e-58 197.7 0.8 2.6e-58 197.3 0.6 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 KFX92902.1 - 7.8e-07 28.3 26.1 0.0088 15.0 15.4 2.3 1 1 1 2 2 2 2 ZIP Zinc transporter Spore_III_AE PF09546.5 KFX92902.1 - 0.16 10.9 2.0 0.17 10.8 0.6 1.5 2 0 0 2 2 2 0 Stage III sporulation protein AE (spore_III_AE) Mito_carr PF00153.22 KFX92904.1 - 4.8e-57 189.6 9.0 7.1e-20 70.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.17 KFX92918.1 - 1.3e-65 219.7 0.5 1.5e-65 219.4 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX92918.1 - 1.1e-21 77.5 0.0 1.7e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFX92918.1 - 2.4e-16 59.4 0.1 2.9e-16 59.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFX92918.1 - 2e-05 23.8 0.1 2.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFX92918.1 - 2.8e-05 23.6 0.2 6e-05 22.5 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFX92918.1 - 5.9e-05 23.0 0.1 9.3e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFX92918.1 - 0.00038 19.7 0.0 0.00055 19.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.24 KFX92918.1 - 0.00049 20.3 0.1 0.094 12.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFX92918.1 - 0.0013 18.9 0.0 0.0025 17.9 0.0 1.7 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.13 KFX92918.1 - 0.003 16.8 0.0 0.02 14.1 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 KFX92918.1 - 0.0088 15.2 0.0 0.025 13.7 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFX92918.1 - 0.016 15.2 0.1 0.065 13.2 0.1 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 KFX92918.1 - 0.021 14.7 0.2 0.067 13.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KFX92918.1 - 0.034 13.6 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 KFX92918.1 - 0.054 13.2 0.1 0.096 12.4 0.0 1.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 KFX92918.1 - 0.063 13.5 0.1 0.12 12.6 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Septin PF00735.13 KFX92918.1 - 0.084 11.8 0.0 0.2 10.6 0.0 1.6 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 KFX92918.1 - 0.089 12.2 0.0 0.93 8.9 0.0 2.2 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Pyr_redox_2 PF07992.9 KFX92927.1 - 3.8e-38 131.4 2.1 8.4e-38 130.2 1.4 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KFX92927.1 - 5.7e-35 119.6 0.2 2.6e-33 114.3 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KFX92927.1 - 1.2e-16 60.8 1.1 1.1e-15 57.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_23 PF13489.1 KFX92927.1 - 6e-11 42.3 0.0 1.7e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX92927.1 - 1.1e-09 38.6 0.0 2.6e-09 37.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX92927.1 - 7.4e-08 32.1 0.0 1.6e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Pyr_redox_3 PF13738.1 KFX92927.1 - 1.7e-07 31.4 0.1 2.8e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_12 PF08242.7 KFX92927.1 - 7.8e-07 29.4 0.0 2.4e-06 27.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX92927.1 - 0.00013 22.4 0.4 0.00054 20.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX92927.1 - 0.0022 18.0 0.0 0.0078 16.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain K_oxygenase PF13434.1 KFX92927.1 - 0.0035 16.3 0.0 0.0092 14.9 0.0 1.7 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.2 KFX92927.1 - 0.006 15.7 0.3 0.0088 15.1 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 KFX92927.1 - 0.018 14.1 0.1 1.8 7.7 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KFX92927.1 - 0.026 13.3 4.1 0.28 9.9 1.1 2.9 3 0 0 3 3 3 0 FAD binding domain AlaDh_PNT_C PF01262.16 KFX92927.1 - 0.09 12.3 0.4 11 5.5 0.0 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 KFX92927.1 - 0.11 11.4 4.4 0.15 10.9 1.9 1.9 1 1 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 KFX92927.1 - 0.15 10.9 1.3 0.41 9.4 0.8 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 KFX92927.1 - 0.33 9.3 5.2 2.6 6.4 0.6 3.1 2 1 0 3 3 3 0 HI0933-like protein NAD_binding_8 PF13450.1 KFX92927.1 - 0.94 9.5 3.4 4.3 7.4 2.3 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Helicase_C PF00271.26 KFX92928.1 - 1.8e-17 62.9 0.1 4.6e-17 61.6 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain FYVE PF01363.16 KFX92929.1 - 1 9.2 8.7 23 4.9 6.1 2.5 1 1 0 1 1 1 0 FYVE zinc finger HypA PF01155.14 KFX92929.1 - 5.1 6.8 7.5 6.6 6.4 0.6 2.5 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family gerPA PF10676.4 KFX92941.1 - 0.16 11.8 2.2 0.23 11.3 0.7 1.9 1 1 1 2 2 2 0 Spore germination protein gerPA/gerPF SAP25 PF15476.1 KFX92941.1 - 0.58 9.6 8.4 0.67 9.4 5.8 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP25 YopE_N PF09020.5 KFX92962.1 - 0.069 13.1 3.5 0.74 9.8 0.1 2.4 2 0 0 2 2 2 0 YopE, N terminal Retinal PF15449.1 KFX92962.1 - 1.9 6.0 4.2 2.4 5.6 2.9 1.0 1 0 0 1 1 1 0 Retinal protein Peptidase_M28 PF04389.12 KFX92963.1 - 1e-34 119.8 0.0 1.4e-34 119.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 DUF3533 PF12051.3 KFX92964.1 - 2e-92 309.9 8.7 2.7e-92 309.4 6.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) APH PF01636.18 KFX92964.1 - 5e-07 29.6 0.2 8.6e-06 25.6 0.0 2.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX92964.1 - 0.0085 15.6 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF2458 PF10454.4 KFX92980.1 - 6.6e-37 126.6 0.0 9.7e-37 126.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) GATA PF00320.22 KFX92984.1 - 4.2e-15 54.8 4.3 7.7e-15 53.9 3.0 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS_3 PF08447.6 KFX92984.1 - 1.2e-14 54.1 0.0 2.8e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 KFX92984.1 - 1.3e-12 47.4 0.0 2.8e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 KFX92984.1 - 1.5e-10 41.3 0.0 4.1e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.1 KFX92984.1 - 7.9e-08 32.2 0.0 1.4e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 KFX92984.1 - 2.8e-06 27.3 0.0 5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 PAS fold DUF3742 PF12553.3 KFX92984.1 - 0.11 12.9 0.4 0.38 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) PHY PF00360.15 KFX92984.1 - 0.12 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Phytochrome region AAA_23 PF13476.1 KFX92985.1 - 8.7e-16 58.8 94.8 5.4e-14 52.9 36.8 6.1 1 1 2 3 3 3 1 AAA domain SMC_N PF02463.14 KFX92985.1 - 1.3e-07 31.0 0.0 1.3e-07 31.0 0.0 2.6 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KFX92985.1 - 3.1e-05 23.2 0.0 3.1e-05 23.2 0.0 4.0 2 1 0 3 3 3 1 AAA ATPase domain AAA_13 PF13166.1 KFX92985.1 - 0.00014 20.5 94.4 0.00031 19.3 0.0 5.1 2 1 2 5 5 5 3 AAA domain AAA_29 PF13555.1 KFX92985.1 - 0.00063 19.2 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad50_zn_hook PF04423.9 KFX92985.1 - 0.003 17.0 0.7 0.003 17.0 0.5 5.3 5 0 0 5 5 5 1 Rad50 zinc hook motif AAA_21 PF13304.1 KFX92985.1 - 0.0096 15.9 1.0 0.023 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KFX92985.1 - 0.011 15.4 0.3 0.057 13.1 0.2 2.3 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KFX92985.1 - 0.061 13.6 0.1 0.061 13.6 0.0 5.6 2 1 1 3 3 3 0 ABC transporter SbcCD_C PF13558.1 KFX92986.1 - 1.6e-12 47.1 0.0 4.4e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 KFX92986.1 - 3.1e-08 33.1 1.0 4.1e-08 32.7 0.7 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain IncA PF04156.9 KFX92986.1 - 3.8e-05 23.3 8.5 6.7e-05 22.5 4.3 2.2 1 1 1 2 2 2 1 IncA protein AAA_21 PF13304.1 KFX92986.1 - 0.00041 20.4 6.0 0.0046 16.9 4.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_13 PF13166.1 KFX92986.1 - 0.0015 17.1 20.2 0.054 11.9 0.5 2.5 2 1 0 2 2 2 2 AAA domain DUF948 PF06103.6 KFX92986.1 - 0.016 15.0 0.1 0.069 13.0 0.1 2.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Tropomyosin_1 PF12718.2 KFX92986.1 - 0.017 14.9 4.2 0.017 14.9 2.9 3.1 3 0 0 3 3 3 0 Tropomyosin like FtsA PF14450.1 KFX92986.1 - 0.054 13.3 0.1 0.19 11.5 0.1 2.1 1 1 0 1 1 1 0 Cell division protein FtsA DUF3373 PF11853.3 KFX92986.1 - 0.067 11.7 2.0 0.081 11.4 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF4140 PF13600.1 KFX92986.1 - 0.12 12.7 0.4 0.12 12.7 0.3 2.8 3 1 1 4 4 3 0 N-terminal domain of unknown function (DUF4140) MIP-T3 PF10243.4 KFX92986.1 - 0.15 10.5 8.6 0.026 12.9 2.5 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Laminin_II PF06009.7 KFX92986.1 - 0.17 11.6 8.6 0.081 12.6 1.9 2.3 2 1 1 3 3 3 0 Laminin Domain II SlyX PF04102.7 KFX92986.1 - 0.61 10.5 2.8 3 8.2 0.2 2.8 2 0 0 2 2 2 0 SlyX BLOC1_2 PF10046.4 KFX92986.1 - 0.86 9.7 9.0 0.4 10.8 0.8 3.3 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ABC_tran PF00005.22 KFX92986.1 - 0.94 9.7 3.3 11 6.2 2.1 2.4 1 1 0 1 1 1 0 ABC transporter TMPIT PF07851.8 KFX92986.1 - 1.1 8.3 4.5 0.63 9.0 0.7 2.1 2 0 0 2 2 2 0 TMPIT-like protein COG2 PF06148.6 KFX92986.1 - 1.1 9.1 6.7 0.3 10.9 1.0 2.6 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.6 KFX92986.1 - 2.2 6.8 16.5 2.3 6.7 7.1 2.7 1 1 0 2 2 2 0 Spc7 kinetochore protein Occludin_ELL PF07303.8 KFX92986.1 - 3.7 8.3 11.6 6.1 7.6 0.1 3.4 3 1 1 4 4 4 0 Occludin homology domain V_ATPase_I PF01496.14 KFX92986.1 - 7 4.3 8.0 8.6 4.0 5.2 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family FlaC_arch PF05377.6 KFX92986.1 - 8.1 6.4 8.8 0.72 9.7 1.2 2.8 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) ECH PF00378.15 KFX92988.1 - 2.9e-40 137.9 0.0 3.7e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Beta-lactamase PF00144.19 KFX92989.1 - 1.2e-26 93.5 0.1 2.1e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase Arginase PF00491.16 KFX92990.1 - 4.7e-83 278.6 0.5 5.9e-83 278.3 0.3 1.0 1 0 0 1 1 1 1 Arginase family SH3_9 PF14604.1 KFX92994.1 - 3.6e-12 45.6 0.1 7.1e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFX92994.1 - 5.7e-11 41.6 0.0 1.2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.12 KFX92994.1 - 1.4e-08 34.4 0.0 2.6e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 KFX92994.1 - 2.4e-07 30.8 0.0 4.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 PH domain SH3_2 PF07653.12 KFX92994.1 - 2.3e-06 27.0 0.1 4.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.1 KFX92994.1 - 5.6e-05 23.3 0.1 0.00014 22.0 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain SAM_1 PF00536.25 KFX92994.1 - 0.0021 18.2 0.0 0.0034 17.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) FAD_binding_8 PF08022.7 KFX92995.1 - 2.1e-16 59.6 0.0 5e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KFX92995.1 - 8.3e-07 29.0 2.7 2.9e-06 27.2 1.9 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 KFX92995.1 - 0.024 14.7 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Pkinase PF00069.20 KFX92999.1 - 1.4e-07 30.9 0.0 2.5e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX92999.1 - 7.1e-05 22.0 0.0 0.00019 20.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Zn_clus PF00172.13 KFX93000.1 - 5.1 7.0 12.1 10 6.1 8.4 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 KFX93002.1 - 6.9e-09 35.2 0.9 4.3e-07 29.5 0.2 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat BicD PF09730.4 KFX93002.1 - 0.09 11.1 13.9 0.13 10.6 9.6 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D FUSC PF04632.7 KFX93002.1 - 0.2 10.0 1.9 0.36 9.1 1.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family TBPIP PF07106.8 KFX93002.1 - 1.5 8.3 16.4 2.4 7.6 11.4 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Hid1 PF12722.2 KFX93002.1 - 3.4 5.2 8.0 4.7 4.7 5.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Suf PF05843.9 KFX93002.1 - 3.7 7.1 9.7 6 6.5 6.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Baculo_p24 PF05073.7 KFX93002.1 - 5.5 6.5 7.6 11 5.5 5.3 1.4 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Peptidase_M1 PF01433.15 KFX93003.1 - 4.6e-138 460.5 0.3 6.3e-138 460.0 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KFX93003.1 - 1.1e-92 310.7 0.1 2.6e-92 309.5 0.0 1.6 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KFX93003.1 - 3e-19 69.3 0.1 6.1e-19 68.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily MFS_1 PF07690.11 KFX93004.1 - 3.2e-33 114.9 26.2 3.2e-33 114.9 18.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX93004.1 - 1e-05 24.3 13.5 1e-05 24.3 9.3 3.4 2 2 1 3 3 3 2 Sugar (and other) transporter DUF4044 PF13253.1 KFX93004.1 - 6 6.1 8.3 3.3 6.9 3.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) CFEM PF05730.6 KFX93005.1 - 1.4e-11 44.0 13.7 2.2e-11 43.4 9.5 1.3 1 0 0 1 1 1 1 CFEM domain DUF1517 PF07466.6 KFX93005.1 - 3.1 6.7 5.8 4.2 6.2 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) CP2 PF04516.10 KFX93006.1 - 4.5e-85 284.4 0.0 6.9e-85 283.8 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.9 KFX93006.1 - 0.017 13.7 0.0 0.027 13.0 0.0 1.2 1 0 0 1 1 1 0 Tektin family Phage_G PF02306.10 KFX93006.1 - 0.042 13.4 0.1 0.042 13.4 0.1 1.9 2 0 0 2 2 2 0 Major spike protein (G protein) Raptor_N PF14538.1 KFX93007.1 - 2.9e-65 218.8 0.0 6.9e-65 217.6 0.0 1.7 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 KFX93007.1 - 1.3e-09 37.5 8.2 0.51 10.3 0.0 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 KFX93007.1 - 5.5e-05 22.9 0.1 0.057 13.2 0.1 2.8 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Atx10homo_assoc PF09759.4 KFX93007.1 - 0.0018 17.9 2.0 0.0019 17.8 0.2 1.8 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain bZIP_1 PF00170.16 KFX93007.1 - 0.0018 18.1 6.3 0.004 17.0 4.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor HEAT_2 PF13646.1 KFX93007.1 - 0.0063 16.7 0.0 1.9 8.8 0.0 3.7 3 1 1 4 4 4 1 HEAT repeats Nup160 PF11715.3 KFX93007.1 - 0.0091 14.1 0.1 0.031 12.4 0.0 1.8 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Cnd1 PF12717.2 KFX93007.1 - 0.17 11.7 0.3 28 4.5 0.0 3.5 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KFX93007.1 - 0.59 10.3 8.6 1.8 8.8 0.2 4.8 6 0 0 6 6 6 0 HEAT repeat ADH_zinc_N PF00107.21 KFX93009.1 - 5.7e-29 100.3 0.2 1.2e-28 99.2 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX93009.1 - 2.8e-15 57.3 0.0 7.2e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX93009.1 - 1.7e-05 24.5 0.0 3.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 KFX93009.1 - 0.0074 15.9 0.2 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 KFX93009.1 - 0.053 12.6 0.1 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ATP-sulfurylase PF01747.12 KFX93010.1 - 2.4e-87 291.7 0.0 3.3e-87 291.3 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 KFX93010.1 - 2.6e-55 186.3 0.1 4.3e-55 185.6 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 KFX93010.1 - 3.7e-51 172.6 0.0 6.1e-51 172.0 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain Complex1_LYR_1 PF13232.1 KFX93011.1 - 1e-19 70.5 5.1 1.3e-19 70.1 3.5 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KFX93011.1 - 1.3e-18 66.5 4.3 1.9e-18 66.0 3.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 KFX93011.1 - 0.0072 16.7 2.1 0.0085 16.5 1.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Pkinase_Tyr PF07714.12 KFX93020.1 - 1.8e-18 66.5 0.0 1.5e-17 63.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFX93020.1 - 3.2e-18 65.8 0.0 4.1e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KFX93020.1 - 0.0059 16.3 2.3 0.013 15.2 1.6 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX93020.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pyr_redox_2 PF07992.9 KFX93021.1 - 1.6e-31 109.7 0.0 2.4e-31 109.1 0.0 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX93021.1 - 4.1e-09 36.7 0.0 6.6e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFX93021.1 - 4.7e-06 26.8 0.0 0.071 13.1 0.0 3.5 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAPRTase PF04095.11 KFX93022.1 - 5.5e-48 163.3 0.0 1.2e-46 159.0 0.0 2.0 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family MFS_1 PF07690.11 KFX93023.1 - 1.9e-19 69.6 74.8 3.2e-14 52.4 30.3 3.2 1 1 2 3 3 3 3 Major Facilitator Superfamily Glyco_hydro_76 PF03663.9 KFX93024.1 - 2.3e-26 93.0 10.6 3.7e-16 59.4 0.8 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 bZIP_1 PF00170.16 KFX93025.1 - 2.5e-06 27.3 8.2 4.7e-06 26.4 5.5 1.5 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFX93025.1 - 0.013 15.3 7.0 0.021 14.6 4.8 1.3 1 0 0 1 1 1 0 Basic region leucine zipper DUF605 PF04652.11 KFX93025.1 - 2.1 7.6 12.5 2.6 7.3 8.7 1.1 1 0 0 1 1 1 0 Vta1 like bZIP_Maf PF03131.12 KFX93025.1 - 4.2 7.7 9.8 2.1 8.7 5.2 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor rRNA_processing PF08524.6 KFX93026.1 - 0.035 13.9 2.8 0.033 13.9 1.7 1.3 1 1 0 1 1 1 0 rRNA processing Mago-bind PF09282.5 KFX93026.1 - 0.059 12.9 0.6 0.059 12.9 0.4 2.1 2 0 0 2 2 2 0 Mago binding E1-E2_ATPase PF00122.15 KFX93027.1 - 1.8e-17 63.1 0.1 2.9e-17 62.4 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_N PF00690.21 KFX93027.1 - 2.3e-10 39.7 0.0 4.3e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus zf-RING_2 PF13639.1 KFX93028.1 - 8.9e-16 57.4 5.8 1.4e-15 56.8 4.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFX93028.1 - 5.5e-10 38.8 4.7 9e-10 38.1 3.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KFX93028.1 - 8.3e-09 35.4 2.0 1.5e-08 34.6 1.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KFX93028.1 - 2.9e-08 33.2 2.8 4.4e-08 32.6 1.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX93028.1 - 2.7e-07 30.1 6.5 4.4e-07 29.4 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFX93028.1 - 3.3e-07 30.2 7.2 5.4e-07 29.5 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFX93028.1 - 7.8e-05 22.4 1.2 0.00016 21.4 0.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KFX93028.1 - 0.0086 15.6 3.5 0.014 14.9 2.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 KFX93028.1 - 0.01 15.5 2.0 0.01 15.5 1.4 2.0 1 1 1 2 2 2 0 RING-type zinc-finger RINGv PF12906.2 KFX93028.1 - 0.01 15.8 2.8 0.023 14.7 1.9 1.6 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 KFX93028.1 - 0.011 15.7 5.7 0.25 11.3 3.9 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_1 PF14446.1 KFX93028.1 - 0.016 14.9 3.1 0.27 11.0 2.2 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Vps39_2 PF10367.4 KFX93028.1 - 0.02 15.0 2.7 1.8 8.7 1.5 2.8 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 C1_1 PF00130.17 KFX93028.1 - 0.048 13.4 2.0 0.32 10.7 0.3 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 KFX93028.1 - 0.051 13.2 2.9 0.092 12.4 2.0 1.5 1 0 0 1 1 1 0 PHD-finger U-box PF04564.10 KFX93028.1 - 0.073 13.0 0.0 0.26 11.2 0.0 1.9 2 0 0 2 2 2 0 U-box domain Prok-RING_4 PF14447.1 KFX93028.1 - 0.085 12.4 3.1 0.21 11.1 2.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 KFX93028.1 - 0.16 11.8 5.5 0.52 10.2 3.8 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.9 KFX93028.1 - 0.19 11.1 0.2 0.19 11.1 0.1 1.9 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-P11 PF03854.9 KFX93028.1 - 0.2 11.1 6.7 0.48 9.9 4.6 1.6 1 1 0 1 1 1 0 P-11 zinc finger GAGA PF09237.6 KFX93028.1 - 0.26 10.9 2.6 1.2 8.8 0.3 2.4 2 0 0 2 2 2 0 GAGA factor zf-Nse PF11789.3 KFX93028.1 - 0.31 10.5 2.7 0.71 9.4 1.9 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit K_trans PF02705.11 KFX93029.1 - 1.2e-180 601.4 27.2 1.5e-180 601.1 18.9 1.0 1 0 0 1 1 1 1 K+ potassium transporter DUF4291 PF14124.1 KFX93030.1 - 4.3e-63 212.2 0.4 5.9e-63 211.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Pro_isomerase PF00160.16 KFX93031.1 - 2.7e-41 141.3 0.0 4.6e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD XAP5 PF04921.9 KFX93031.1 - 1.4 8.4 5.3 0.28 10.7 0.5 2.0 2 0 0 2 2 2 0 XAP5, circadian clock regulator TFIIA_gamma_C PF02751.9 KFX93032.1 - 2.7e-08 33.5 0.9 4.4e-08 32.8 0.6 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 KFX93032.1 - 6.4e-07 28.8 0.0 1.1e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain APH PF01636.18 KFX93034.1 - 3.3e-07 30.2 0.0 2.8e-06 27.2 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KFX93034.1 - 0.014 14.3 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase 4HBT PF03061.17 KFX93047.1 - 6.7e-08 32.5 0.0 9.8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 KFX93047.1 - 7.6e-06 26.3 0.0 9.3e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 KFX93047.1 - 0.00048 19.1 0.2 0.00067 18.6 0.1 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase SNF2_N PF00176.18 KFX93048.1 - 9.8e-26 90.2 0.3 1.8e-18 66.4 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 KFX93048.1 - 3.7e-16 59.1 0.0 1.1e-15 57.6 0.0 1.9 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase zf-RING_5 PF14634.1 KFX93048.1 - 0.0027 17.3 15.9 0.0038 16.9 4.8 2.6 2 0 0 2 2 2 2 zinc-RING finger domain Pyr_redox_2 PF07992.9 KFX93049.1 - 9.6e-16 58.2 0.0 1.3e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFX93049.1 - 4e-05 22.2 0.0 0.0086 14.5 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 KFX93049.1 - 0.00012 22.1 0.3 0.12 12.3 0.0 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFX93049.1 - 0.0002 20.3 0.6 0.39 9.5 0.0 2.3 1 1 1 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KFX93049.1 - 0.0018 18.0 0.2 0.45 10.2 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 KFX93049.1 - 0.0018 17.2 0.4 0.27 10.0 0.1 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFX93049.1 - 0.034 12.9 0.1 0.088 11.6 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.1 KFX93049.1 - 0.13 11.1 0.0 3.7 6.3 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) AA_permease_N PF08403.5 KFX93050.1 - 0.064 12.5 0.8 2.9 7.2 0.0 2.9 3 0 0 3 3 3 0 Amino acid permease N-terminal TPR_12 PF13424.1 KFX93053.1 - 1.4e-49 165.9 15.5 3.8e-14 52.3 2.0 7.7 6 2 1 7 7 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 KFX93053.1 - 1.4e-37 126.5 26.0 8.2e-07 28.7 0.1 10.6 10 0 0 10 10 10 6 Tetratricopeptide repeat NB-ARC PF00931.17 KFX93053.1 - 4.5e-19 68.3 0.0 8.1e-19 67.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.1 KFX93053.1 - 1.8e-17 62.2 21.6 0.013 16.1 0.1 10.0 6 3 5 11 11 11 5 Tetratricopeptide repeat TPR_11 PF13414.1 KFX93053.1 - 2.3e-16 59.1 12.7 3.1e-07 29.9 1.9 6.6 4 2 2 6 6 6 3 TPR repeat TPR_16 PF13432.1 KFX93053.1 - 9.1e-16 58.0 15.1 5.3e-05 23.7 2.3 6.7 3 2 4 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFX93053.1 - 1.5e-14 54.0 10.4 2.9e-05 24.2 0.8 7.2 4 2 4 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 KFX93053.1 - 4.2e-12 44.9 27.5 0.0061 16.3 0.8 9.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFX93053.1 - 1.5e-08 33.7 14.3 1.4 8.8 0.0 8.4 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_4 PF07721.9 KFX93053.1 - 2.1e-08 33.8 11.4 0.37 11.3 0.1 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 KFX93053.1 - 5.9e-08 32.7 7.1 0.00064 19.8 1.0 4.5 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KFX93053.1 - 5.3e-06 25.8 19.7 0.066 12.8 0.5 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat AAA_16 PF13191.1 KFX93053.1 - 1.4e-05 25.1 0.3 0.00012 22.1 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain TPR_17 PF13431.1 KFX93053.1 - 2.1e-05 24.3 0.2 0.28 11.4 0.3 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFX93053.1 - 2.2e-05 24.6 13.5 1.1 9.8 0.1 7.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFX93053.1 - 0.00022 20.7 15.1 0.14 12.0 0.2 7.2 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_20 PF14561.1 KFX93053.1 - 0.00039 20.4 9.7 0.28 11.3 0.6 6.0 8 0 0 8 8 7 1 Tetratricopeptide repeat AAA_22 PF13401.1 KFX93053.1 - 0.00086 19.4 0.0 0.0037 17.4 0.0 2.1 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 KFX93053.1 - 0.0014 18.2 0.0 0.0032 17.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_5 PF12688.2 KFX93053.1 - 0.017 15.1 4.5 4.4 7.3 0.9 3.9 1 1 0 3 3 3 0 Tetratrico peptide repeat ADH_zinc_N PF00107.21 KFX93054.1 - 2.3e-10 40.0 0.0 3.8e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX93054.1 - 2.8e-10 39.9 0.0 4.6e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFX93054.1 - 0.014 16.2 0.1 0.03 15.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Fungal_trans PF04082.13 KFX93055.1 - 5.7e-29 100.7 0.6 1e-28 99.9 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX93055.1 - 8.8e-08 31.9 15.8 2.2e-07 30.6 10.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.5 KFX93055.1 - 2.4 8.3 8.1 29 4.8 0.0 2.7 2 0 0 2 2 2 0 Opy2 protein DUF2633 PF11119.3 KFX93060.1 - 0.18 11.5 0.0 0.49 10.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2633) Choline_kinase PF01633.15 KFX93061.1 - 0.0082 15.7 0.0 0.032 13.8 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase CAML PF14963.1 KFX93061.1 - 0.042 13.1 3.6 0.078 12.3 2.5 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Host_attach PF10116.4 KFX93061.1 - 0.51 10.5 5.4 11 6.2 1.7 2.4 2 0 0 2 2 2 0 Protein required for attachment to host cells TauD PF02668.11 KFX93063.1 - 2.7e-42 145.2 0.0 4.7e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 KFX93064.1 - 3.1e-23 82.0 21.0 4.5e-23 81.5 14.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KFX93064.1 - 9.5e-15 54.1 0.0 2.5e-14 52.7 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF2104 PF09877.4 KFX93064.1 - 0.089 12.7 1.5 0.13 12.1 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) DUF3712 PF12505.3 KFX93065.1 - 3.5e-40 136.9 2.9 7.2e-39 132.6 0.6 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3712) DUF2236 PF09995.4 KFX93066.1 - 2.5e-57 193.9 2.4 3.1e-57 193.6 1.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Fungal_trans PF04082.13 KFX93068.1 - 7.4e-06 25.0 1.5 1.1e-05 24.4 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Trp_oprn_chp PF09534.5 KFX93068.1 - 0.55 9.8 6.1 0.31 10.6 1.8 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) AMP-binding PF00501.23 KFX93069.1 - 1.5e-75 254.1 0.0 1.9e-75 253.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX93069.1 - 3.6e-15 56.6 0.2 8.1e-15 55.5 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acyl-CoA_dh_1 PF00441.19 KFX93070.1 - 2.7e-32 111.9 0.3 4.4e-32 111.2 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFX93070.1 - 3.4e-21 74.4 1.2 6.3e-21 73.6 0.8 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KFX93070.1 - 4.6e-16 59.4 0.0 1.4e-15 57.8 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KFX93070.1 - 2.4e-06 27.8 0.2 4e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain FMO-like PF00743.14 KFX93071.1 - 1e-28 99.8 0.0 1.2e-11 43.5 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFX93071.1 - 2.2e-21 76.8 0.2 3.6e-20 72.8 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFX93071.1 - 4.2e-08 33.3 0.0 4e-06 26.8 0.0 2.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX93071.1 - 3.3e-07 30.2 0.7 0.0016 18.1 0.0 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KFX93071.1 - 3.7e-07 29.3 1.8 0.00017 20.6 0.1 3.5 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KFX93071.1 - 8.3e-05 22.5 0.8 0.00026 20.9 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFX93071.1 - 0.011 14.9 1.1 0.36 9.9 0.1 2.2 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.15 KFX93071.1 - 0.031 14.3 0.3 0.41 10.7 0.1 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KFX93071.1 - 0.082 13.3 1.1 9.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFX93071.1 - 0.1 11.6 0.6 0.22 10.5 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 KFX93071.1 - 0.31 9.4 3.0 0.2 10.0 0.5 1.8 2 0 0 2 2 2 0 HI0933-like protein MFS_1 PF07690.11 KFX93072.1 - 1.1e-32 113.1 24.2 2.1e-32 112.2 16.8 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Inhibitor_I68 PF10468.4 KFX93073.1 - 0.2 11.8 0.5 0.2 11.8 0.3 1.8 2 1 0 2 2 2 0 Carboxypeptidase inhibitor I68 OHCU_decarbox PF09349.5 KFX93075.1 - 3.7e-45 154.0 0.0 4.2e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase GPI-anchored PF10342.4 KFX93088.1 - 5.3e-12 46.0 0.0 7.6e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cyclin PF08613.6 KFX93089.1 - 1.7e-40 138.8 0.0 2.1e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KFX93089.1 - 0.011 15.3 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain DUF3301 PF11743.3 KFX93089.1 - 0.13 11.7 0.0 9.7 5.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3301) ATP11 PF06644.6 KFX93093.1 - 2.6e-88 296.0 0.0 3e-88 295.8 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein RHH_1 PF01402.16 KFX93093.1 - 0.73 9.8 2.6 2.1 8.3 0.3 2.8 2 1 1 3 3 3 0 Ribbon-helix-helix protein, copG family AMP-binding PF00501.23 KFX93094.1 - 6.2e-94 314.7 0.0 7.4e-94 314.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX93094.1 - 1.5e-11 45.0 0.1 4.4e-11 43.5 0.1 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Fungal_trans_2 PF11951.3 KFX93095.1 - 2.7e-57 194.1 0.7 3.7e-57 193.6 0.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX93095.1 - 3.4e-08 33.2 8.0 6.3e-08 32.4 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.16 KFX93096.1 - 6.7e-51 172.5 0.1 1.4e-50 171.5 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 KFX93096.1 - 9.2e-14 50.7 0.3 7.1e-08 32.0 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat Far-17a_AIG1 PF04750.9 KFX93097.1 - 5.5e-59 198.7 13.6 6.3e-59 198.5 9.4 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein eIF2A PF08662.6 KFX93098.1 - 2.3e-37 128.6 3.4 5.9e-36 123.9 0.2 3.6 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 KFX93098.1 - 1.4e-06 27.8 0.0 2.7e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX93098.1 - 1.7e-05 24.5 0.0 3.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX93098.1 - 0.00024 21.0 0.0 0.00054 19.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KFX93098.1 - 0.00093 18.9 0.4 0.095 12.6 0.0 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat Cpn60_TCP1 PF00118.19 KFX93099.1 - 1.1e-131 439.8 10.3 1.3e-131 439.6 7.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GARS_C PF02843.11 KFX93099.1 - 0.18 11.9 1.8 0.43 10.7 0.1 2.5 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain Response_reg PF00072.19 KFX93104.1 - 1.3e-16 60.6 0.0 1.6e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Velvet PF11754.3 KFX93107.1 - 2.5e-14 53.3 1.0 4.8e-14 52.4 0.7 1.5 1 0 0 1 1 1 1 Velvet factor DUF605 PF04652.11 KFX93107.1 - 0.55 9.5 14.5 0.68 9.2 10.1 1.1 1 0 0 1 1 1 0 Vta1 like UbiA PF01040.13 KFX93110.1 - 3.3e-32 111.7 23.2 4.7e-32 111.2 16.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Tropomyosin PF00261.15 KFX93117.1 - 0.008 15.2 16.5 0.016 14.2 10.3 2.0 2 0 0 2 2 2 1 Tropomyosin Tropomyosin_1 PF12718.2 KFX93117.1 - 0.013 15.3 16.1 0.17 11.7 9.9 2.3 2 0 0 2 2 2 0 Tropomyosin like TMF_DNA_bd PF12329.3 KFX93117.1 - 0.24 11.2 15.6 1.8 8.3 0.2 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.6 KFX93117.1 - 0.39 9.3 5.1 0.66 8.5 3.5 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 KFX93117.1 - 0.58 9.7 8.7 0.015 14.9 1.5 1.6 2 0 0 2 2 2 0 IncA protein Macoilin PF09726.4 KFX93117.1 - 0.61 8.3 12.2 0.017 13.4 4.3 1.3 2 0 0 2 2 2 0 Transmembrane protein GAS PF13851.1 KFX93117.1 - 0.68 9.0 6.6 1.5 7.9 3.3 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.15 KFX93117.1 - 1.6 8.5 9.7 6.9 6.4 1.1 3.2 2 1 1 3 3 3 0 Prefoldin subunit FUSC PF04632.7 KFX93117.1 - 4 5.7 4.0 6.5 5.0 2.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-U1 PF06220.7 KFX93120.1 - 1.3e-22 79.0 3.4 1.7e-22 78.6 2.4 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 KFX93120.1 - 0.0076 16.3 4.6 0.028 14.5 3.2 1.9 1 1 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AKAP95 PF04988.7 KFX93120.1 - 0.039 13.7 0.1 0.042 13.6 0.1 1.1 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) EMP24_GP25L PF01105.19 KFX93121.1 - 2.9e-51 173.8 0.8 1.2e-25 90.2 0.1 2.0 1 1 1 2 2 2 2 emp24/gp25L/p24 family/GOLD EzrA PF06160.7 KFX93121.1 - 0.0038 15.4 4.4 0.009 14.2 3.1 1.5 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA STAT_alpha PF01017.15 KFX93121.1 - 0.0082 15.8 2.6 0.17 11.6 0.7 2.1 1 1 1 2 2 2 2 STAT protein, all-alpha domain LOH1CR12 PF10158.4 KFX93121.1 - 0.023 14.4 1.6 5 6.9 0.1 2.2 1 1 1 2 2 2 0 Tumour suppressor protein DUF342 PF03961.8 KFX93121.1 - 0.024 13.0 0.3 0.035 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Lyase_8_N PF08124.6 KFX93121.1 - 0.036 12.9 1.5 0.051 12.4 1.0 1.1 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Allexi_40kDa PF05549.6 KFX93121.1 - 0.037 13.3 0.3 0.051 12.8 0.2 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Spore_III_AB PF09548.5 KFX93121.1 - 0.042 13.5 0.1 2 8.1 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Sec8_exocyst PF04048.9 KFX93121.1 - 0.061 12.9 0.3 1.7 8.2 0.2 2.3 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain MAD PF05557.8 KFX93121.1 - 0.065 11.3 2.7 0.087 10.9 1.9 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Noelin-1 PF12308.3 KFX93121.1 - 0.066 13.0 2.0 0.26 11.1 0.3 2.2 1 1 1 2 2 2 0 Neurogenesis glycoprotein MCPsignal PF00015.16 KFX93121.1 - 0.11 11.9 0.7 0.38 10.2 0.3 1.7 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain NEP PF10167.4 KFX93121.1 - 0.15 11.7 0.9 0.66 9.6 0.5 1.9 1 1 1 2 2 2 0 Uncharacterised conserved protein WASH_WAHD PF11945.3 KFX93121.1 - 0.21 10.8 2.7 5.3 6.2 0.1 2.2 1 1 1 2 2 2 0 WAHD domain of WASH complex Vps51 PF08700.6 KFX93121.1 - 0.25 11.1 1.6 23 4.8 0.1 2.8 2 1 0 2 2 2 0 Vps51/Vps67 APG6 PF04111.7 KFX93121.1 - 0.31 10.0 2.2 0.4 9.6 1.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DegS PF05384.6 KFX93121.1 - 0.31 10.2 6.0 1.1 8.4 0.9 2.2 1 1 1 2 2 2 0 Sensor protein DegS AcylCoA_dehyd_C PF12186.3 KFX93121.1 - 0.32 10.8 3.2 4 7.3 0.3 2.5 2 1 1 3 3 2 0 Acyl-CoA dehydrogenase C terminal Laminin_II PF06009.7 KFX93121.1 - 0.36 10.5 2.2 0.65 9.7 1.5 1.4 1 0 0 1 1 1 0 Laminin Domain II DUF4140 PF13600.1 KFX93121.1 - 0.4 11.1 3.0 11 6.5 0.3 2.5 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) DMPK_coil PF08826.5 KFX93121.1 - 1.2 9.0 4.5 5.9 6.8 0.1 2.5 3 0 0 3 3 2 0 DMPK coiled coil domain like Cir_N PF10197.4 KFX93121.1 - 1.5 8.9 8.1 8.7 6.4 0.4 2.7 3 0 0 3 3 3 0 N-terminal domain of CBF1 interacting co-repressor CIR DUF972 PF06156.8 KFX93121.1 - 3.2 8.1 6.5 2.6 8.4 1.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Latarcin PF10279.4 KFX93121.1 - 4 7.6 6.0 1.7e+02 2.4 4.1 2.3 1 1 0 1 1 1 0 Latarcin precursor gag-asp_proteas PF13975.1 KFX93122.1 - 0.0027 17.5 0.0 0.0062 16.3 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Alg14 PF08660.6 KFX93124.1 - 1.4e-33 116.2 0.0 1.9e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like KOW PF00467.24 KFX93125.1 - 1.2e-05 24.7 0.2 2.7e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 KOW motif Ras PF00071.17 KFX93126.1 - 9e-56 187.7 0.0 1e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX93126.1 - 9.4e-16 58.3 0.0 1.5e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFX93126.1 - 3.2e-07 29.7 0.0 5.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFX93126.1 - 0.00071 19.0 0.0 0.0032 16.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFX93126.1 - 0.0015 17.8 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KFX93126.1 - 0.026 13.6 0.0 0.038 13.1 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KFX93126.1 - 0.11 11.9 0.0 11 5.4 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Choline_transpo PF04515.7 KFX93128.1 - 7e-101 337.2 31.0 7e-101 337.2 21.5 2.0 2 0 0 2 2 2 1 Plasma-membrane choline transporter Cellulase PF00150.13 KFX93129.1 - 1.6e-45 155.5 0.0 2.2e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Extensin_2 PF04554.8 KFX93132.1 - 4.9 7.0 13.6 11 5.9 9.4 1.7 1 1 0 1 1 1 0 Extensin-like region DUF1681 PF07933.9 KFX93133.1 - 8.5e-34 116.4 0.0 1.1e-33 116.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Tom37 PF10568.4 KFX93135.1 - 8.3e-09 35.5 0.0 1.3e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Tom37_C PF11801.3 KFX93135.1 - 0.0057 16.5 0.0 0.0071 16.2 0.0 1.1 1 0 0 1 1 1 1 Tom37 C-terminal domain MIP PF00230.15 KFX93140.1 - 4.5e-49 166.9 4.1 5.6e-49 166.6 2.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein NUP PF06516.6 KFX93141.1 - 7e-121 402.8 0.0 8.4e-121 402.6 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) p450 PF00067.17 KFX93143.1 - 1.8e-64 217.9 0.0 2.1e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MotB_plug PF13677.1 KFX93143.1 - 0.083 12.2 0.1 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB CFEM PF05730.6 KFX93144.1 - 1e-13 50.8 10.8 1.8e-13 50.0 7.5 1.4 1 0 0 1 1 1 1 CFEM domain Abhydrolase_6 PF12697.2 KFX93145.1 - 2.1e-09 37.6 2.2 3.2e-09 37.0 1.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KFX93145.1 - 0.0057 15.3 0.0 0.0082 14.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KFX93145.1 - 0.011 15.4 0.0 0.017 14.9 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family RNA_polI_A34 PF08208.6 KFX93146.1 - 3.2e-15 56.3 8.4 3.8e-15 56.0 5.8 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 RNase_H2-Ydr279 PF09468.5 KFX93146.1 - 0.059 12.5 8.2 0.06 12.5 5.7 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Paf1 PF03985.8 KFX93146.1 - 0.56 8.8 8.3 0.63 8.7 5.8 1.0 1 0 0 1 1 1 0 Paf1 Methyltransf_26 PF13659.1 KFX93149.1 - 4.8e-17 62.0 0.2 6.7e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX93149.1 - 0.00046 19.6 0.0 0.0044 16.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KFX93149.1 - 0.0019 18.5 0.0 0.0036 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX93149.1 - 0.018 14.6 0.0 0.24 11.0 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KFX93149.1 - 0.042 14.3 0.0 0.07 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KFX93149.1 - 0.044 14.2 0.1 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain A_deaminase PF00962.17 KFX93163.1 - 2.2e-72 243.7 0.0 2.5e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_4 PF13147.1 KFX93163.1 - 0.015 15.3 0.1 0.025 14.6 0.1 1.4 1 1 0 1 1 1 0 Amidohydrolase MFS_1 PF07690.11 KFX93165.1 - 1.3e-17 63.6 27.9 2e-17 62.9 19.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFX93165.1 - 0.29 9.5 16.5 0.02 13.2 5.8 2.1 1 1 0 2 2 2 0 MFS/sugar transport protein PAP_central PF04928.12 KFX93166.1 - 3.3e-105 350.4 0.0 4.7e-105 349.9 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KFX93166.1 - 9.2e-47 158.4 0.2 2.6e-46 157.0 0.1 1.8 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KFX93166.1 - 3.7e-08 33.5 0.1 1e-07 32.1 0.1 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Sec63 PF02889.11 KFX93167.1 - 6.5e-45 153.6 0.0 3.6e-44 151.2 0.0 1.9 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 KFX93167.1 - 8.9e-17 60.5 1.3 2e-16 59.4 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain 7tm_1 PF00001.16 KFX93167.1 - 0.11 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Ras PF00071.17 KFX93171.1 - 5.9e-13 48.5 0.1 6.2e-13 48.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX93171.1 - 7.8e-05 23.1 0.0 8e-05 23.1 0.0 1.0 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFX93171.1 - 0.042 13.0 0.0 0.047 12.9 0.0 1.0 1 0 0 1 1 1 0 ADP-ribosylation factor family DUF3716 PF12511.3 KFX93185.1 - 0.005 16.4 3.8 0.0088 15.6 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Zn_clus PF00172.13 KFX93185.1 - 0.045 13.6 8.1 0.29 11.0 5.7 2.0 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_E10 PF04805.7 KFX93185.1 - 0.072 12.6 0.4 0.13 11.7 0.3 1.4 1 0 0 1 1 1 0 E10-like protein conserved region V-SNARE_C PF12352.3 KFX93185.1 - 0.12 12.4 1.9 0.21 11.6 1.3 1.5 1 1 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus DUF1212 PF06738.7 KFX93186.1 - 8.1e-50 168.9 8.8 2.4e-45 154.3 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KFX93186.1 - 3.6e-28 98.1 8.4 3.6e-28 98.1 5.8 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3815) Bac_export_3 PF01313.14 KFX93188.1 - 0.063 12.9 0.6 0.96 9.1 0.0 2.1 2 0 0 2 2 2 0 Bacterial export proteins, family 3 Glyco_hydro_18 PF00704.23 KFX93190.1 - 1.4e-43 149.7 3.6 2.3e-43 148.9 2.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KFX93190.1 - 2.5e-06 27.2 0.9 0.076 12.9 0.0 3.2 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.14 KFX93190.1 - 0.0036 17.2 3.1 0.0036 17.2 2.1 3.2 2 0 0 2 2 2 1 Chitin recognition protein RTA1 PF04479.8 KFX93191.1 - 3.3e-27 95.4 3.8 4.4e-27 95.0 2.6 1.1 1 0 0 1 1 1 1 RTA1 like protein Radical_SAM PF04055.16 KFX93193.1 - 7.4e-13 48.9 0.0 1.4e-12 48.1 0.0 1.5 1 1 0 1 1 1 1 Radical SAM superfamily SKG6 PF08693.5 KFX93198.1 - 3.1e-06 26.4 2.7 8.7e-06 24.9 1.9 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 KFX93198.1 - 0.0049 16.3 0.0 0.008 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 KFX93198.1 - 0.009 15.7 2.3 0.15 11.7 1.6 2.4 1 1 0 1 1 1 1 TMEM154 protein family CcmD PF04995.9 KFX93198.1 - 0.04 13.6 2.8 0.074 12.7 1.9 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Herpes_gE PF02480.11 KFX93198.1 - 0.053 11.7 0.0 0.053 11.7 0.0 1.9 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E MLANA PF14991.1 KFX93198.1 - 0.091 12.7 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein melan-A Rifin_STEVOR PF02009.11 KFX93198.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family DUF3301 PF11743.3 KFX93198.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) CcmH PF03918.9 KFX93198.1 - 0.17 10.8 0.1 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C biogenesis protein tRNA_anti-codon PF01336.20 KFX93200.1 - 0.00015 21.5 0.0 0.00045 20.0 0.0 1.8 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain Glyco_transf_7N PF13733.1 KFX93200.1 - 0.018 14.4 0.2 0.033 13.5 0.2 1.3 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 ADH_N PF08240.7 KFX93201.1 - 3.6e-23 81.4 4.8 5.8e-23 80.7 3.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX93201.1 - 6.1e-15 54.9 0.0 3.3e-14 52.5 0.0 2.3 2 1 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KFX93201.1 - 0.0014 18.1 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 KFX93201.1 - 0.0028 16.8 0.0 0.0046 16.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 KFX93201.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF2823 PF11034.3 KFX93202.1 - 1.5e-30 105.1 12.7 1.6e-30 104.9 8.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) Phe_tRNA-synt_N PF02912.13 KFX93202.1 - 0.12 12.0 1.9 0.17 11.6 1.0 1.5 1 1 1 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain Glyco_transf_20 PF00982.16 KFX93205.1 - 1.7e-147 491.7 0.0 3.1e-147 490.8 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KFX93205.1 - 1.5e-77 259.6 0.0 3.5e-77 258.4 0.0 1.6 2 0 0 2 2 2 1 Trehalose-phosphatase Glyco_trans_1_4 PF13692.1 KFX93205.1 - 0.0069 16.5 0.0 0.023 14.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 KFX93205.1 - 0.01 15.2 0.0 0.069 12.5 0.0 2.3 2 1 0 2 2 2 0 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 KFX93205.1 - 0.045 13.2 0.0 0.095 12.1 0.0 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain ABC_membrane PF00664.18 KFX93206.1 - 6.7e-36 124.1 11.9 6.7e-36 124.1 8.2 3.5 4 0 0 4 4 3 1 ABC transporter transmembrane region ABC_tran PF00005.22 KFX93206.1 - 1.1e-34 119.7 0.0 2.2e-34 118.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter MFS_1 PF07690.11 KFX93206.1 - 3.2e-30 105.0 45.2 3.2e-30 105.0 31.3 2.7 3 0 0 3 3 3 1 Major Facilitator Superfamily Metallophos PF00149.23 KFX93206.1 - 5.4e-10 38.9 2.8 1.2e-09 37.8 2.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFX93206.1 - 1.7e-09 37.7 0.0 5e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain AAA_21 PF13304.1 KFX93206.1 - 1.1e-06 28.8 0.0 0.0029 17.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KFX93206.1 - 1.8e-05 24.0 0.0 0.0054 15.9 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFX93206.1 - 0.00015 21.8 0.0 0.00058 19.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KFX93206.1 - 0.0002 22.1 0.0 0.00076 20.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain DUF258 PF03193.11 KFX93206.1 - 0.0007 18.8 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA PF00004.24 KFX93206.1 - 0.00077 19.6 0.0 0.099 12.8 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KFX93206.1 - 0.0017 18.2 0.0 0.01 15.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFX93206.1 - 0.0039 17.3 0.0 0.018 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KFX93206.1 - 0.0045 17.4 0.0 0.57 10.6 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein DUF912 PF06024.7 KFX93206.1 - 0.0062 16.5 0.1 0.017 15.1 0.1 1.7 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) AAA_29 PF13555.1 KFX93206.1 - 0.0065 15.9 0.1 0.018 14.5 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 KFX93206.1 - 0.0071 15.8 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA-like domain MMR_HSR1 PF01926.18 KFX93206.1 - 0.026 14.4 0.0 0.31 11.0 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_25 PF13481.1 KFX93206.1 - 0.042 13.2 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFX93206.1 - 0.043 14.1 0.0 0.14 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFX93206.1 - 0.086 12.8 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 KFX93206.1 - 0.12 11.0 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein MobB PF03205.9 KFX93206.1 - 0.13 11.9 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 KFX93206.1 - 0.15 11.1 0.0 0.39 9.7 0.0 1.6 2 0 0 2 2 1 0 Zeta toxin SbcCD_C PF13558.1 KFX93206.1 - 0.21 11.5 0.2 1.1 9.2 0.2 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.17 KFX93206.1 - 0.3 9.9 0.0 0.51 9.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.1 KFX93206.1 - 0.4 10.9 0.0 0.72 10.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Bac_luciferase PF00296.15 KFX93207.1 - 3.4e-62 210.3 0.0 4.6e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase NMO PF03060.10 KFX93207.1 - 0.023 13.8 0.0 2.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase MFS_1 PF07690.11 KFX93208.1 - 1.4e-31 109.5 25.6 1.4e-31 109.5 17.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1614 PF07758.6 KFX93208.1 - 0.044 13.5 1.0 0.14 11.8 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1614) MFS_1 PF07690.11 KFX93209.1 - 5.7e-25 87.7 22.4 5.7e-25 87.7 15.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Pyr_redox_3 PF13738.1 KFX93210.1 - 1.4e-21 77.5 0.1 3.4e-21 76.2 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFX93210.1 - 1.2e-17 63.3 0.5 3e-17 62.0 0.0 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KFX93210.1 - 2.5e-10 40.1 0.0 9.2e-10 38.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFX93210.1 - 5.7e-06 25.4 0.0 0.0034 16.3 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KFX93210.1 - 8.7e-06 24.8 0.1 6.4e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KFX93210.1 - 0.0011 18.8 0.0 0.0026 17.6 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX93210.1 - 0.0029 17.3 0.1 0.11 12.2 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 KFX93210.1 - 0.037 13.1 0.5 0.075 12.1 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Mqo PF06039.10 KFX93210.1 - 0.11 10.6 0.4 2.6 6.1 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Luteo_coat PF00894.13 KFX93217.1 - 0.11 12.3 0.1 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Luteovirus coat protein ABC_tran PF00005.22 KFX93219.1 - 2.8e-42 144.2 0.0 3.9e-21 75.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KFX93219.1 - 1.4e-12 47.6 13.7 3.4e-09 36.5 1.2 2.6 2 1 1 3 3 3 2 ABC transporter transmembrane region T2SE PF00437.15 KFX93219.1 - 2.6e-10 39.6 0.1 0.00029 19.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 KFX93219.1 - 7.9e-09 34.9 0.6 0.0026 17.2 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 KFX93219.1 - 9.2e-09 34.8 0.5 0.0038 16.4 0.0 3.9 2 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KFX93219.1 - 1.3e-07 31.7 0.1 0.016 15.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.1 KFX93219.1 - 3e-07 30.6 0.3 0.4 10.5 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KFX93219.1 - 3.3e-07 30.4 0.5 0.016 15.2 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KFX93219.1 - 4e-07 29.7 0.1 0.0027 17.2 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_33 PF13671.1 KFX93219.1 - 2.7e-06 27.2 0.1 0.067 13.0 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KFX93219.1 - 3.6e-06 27.8 0.1 0.16 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KFX93219.1 - 5.7e-06 25.6 0.5 0.054 12.6 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 KFX93219.1 - 6.2e-06 26.7 0.1 0.053 14.0 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_23 PF13476.1 KFX93219.1 - 6.8e-06 26.5 0.4 0.025 14.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KFX93219.1 - 2.1e-05 24.4 0.0 0.4 10.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 KFX93219.1 - 3.5e-05 23.2 0.8 0.21 10.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 KFX93219.1 - 4.9e-05 23.1 0.3 0.37 10.4 0.0 3.2 3 0 0 3 3 3 1 Archaeal ATPase AAA_18 PF13238.1 KFX93219.1 - 7.5e-05 23.0 0.2 0.69 10.2 0.1 2.6 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 KFX93219.1 - 8.9e-05 21.9 1.6 0.055 12.9 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 KFX93219.1 - 9e-05 22.0 1.9 0.17 11.3 0.1 2.7 3 0 0 3 3 2 2 AAA-like domain MMR_HSR1 PF01926.18 KFX93219.1 - 9.1e-05 22.4 0.0 0.26 11.2 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase NTPase_1 PF03266.10 KFX93219.1 - 0.00022 20.9 0.2 0.25 11.0 0.0 2.5 2 0 0 2 2 2 1 NTPase Zeta_toxin PF06414.7 KFX93219.1 - 0.00035 19.7 0.2 0.54 9.3 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin MobB PF03205.9 KFX93219.1 - 0.00042 20.0 0.9 0.47 10.1 0.1 2.9 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_ATPase PF09818.4 KFX93219.1 - 0.00045 18.9 0.9 0.46 9.0 0.0 3.7 4 0 0 4 4 4 1 Predicted ATPase of the ABC class AAA_19 PF13245.1 KFX93219.1 - 0.00081 19.0 0.6 0.067 12.9 0.1 3.0 2 0 0 2 2 2 1 Part of AAA domain Dynamin_N PF00350.18 KFX93219.1 - 0.00082 19.2 0.5 0.46 10.2 0.0 2.4 2 0 0 2 2 2 1 Dynamin family NACHT PF05729.7 KFX93219.1 - 0.00085 19.0 1.3 0.68 9.5 0.1 2.8 2 0 0 2 2 2 1 NACHT domain Adeno_IVa2 PF02456.10 KFX93219.1 - 0.0014 17.3 0.1 0.13 10.9 0.0 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein Viral_helicase1 PF01443.13 KFX93219.1 - 0.0046 16.5 0.1 2.7 7.4 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 KFX93219.1 - 0.0058 16.2 1.2 0.12 12.0 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 TrwB_AAD_bind PF10412.4 KFX93219.1 - 0.0078 14.8 0.7 1.2 7.7 0.1 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain Mg_chelatase PF01078.16 KFX93219.1 - 0.0079 15.3 0.1 2.4 7.2 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Pox_A32 PF04665.7 KFX93219.1 - 0.012 14.9 0.3 4.3 6.5 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_30 PF13604.1 KFX93219.1 - 0.013 15.1 0.1 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KFX93219.1 - 0.015 15.4 0.0 5.3 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DAP3 PF10236.4 KFX93219.1 - 0.016 14.1 1.3 0.79 8.6 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 DUF815 PF05673.8 KFX93219.1 - 0.019 13.8 0.2 3.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DEAD PF00270.24 KFX93219.1 - 0.02 14.4 0.1 1.1 8.6 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase ATP_bind_1 PF03029.12 KFX93219.1 - 0.023 14.2 0.4 5.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MutS_V PF00488.16 KFX93219.1 - 0.039 13.3 0.1 0.27 10.5 0.0 2.2 2 0 0 2 2 2 0 MutS domain V SbcCD_C PF13558.1 KFX93219.1 - 0.04 13.8 0.5 0.52 10.2 0.3 2.9 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 KFX93219.1 - 0.044 13.5 1.6 17 5.1 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 KFX93219.1 - 0.048 13.2 0.2 9.6 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KFX93219.1 - 0.064 13.4 0.2 2.7 8.1 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) RNA12 PF10443.4 KFX93219.1 - 0.089 11.2 0.2 0.82 8.0 0.0 2.0 2 0 0 2 2 2 0 RNA12 protein PduV-EutP PF10662.4 KFX93219.1 - 0.097 12.1 2.5 10 5.5 0.0 2.9 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Guanylate_kin PF00625.16 KFX93219.1 - 0.12 11.7 0.3 3.6 7.0 0.0 2.9 3 0 0 3 3 2 0 Guanylate kinase APS_kinase PF01583.15 KFX93219.1 - 0.14 11.8 0.8 2.8 7.5 0.1 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase GTP_EFTU PF00009.22 KFX93219.1 - 0.15 11.4 0.0 9.8 5.5 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Septin PF00735.13 KFX93219.1 - 0.17 10.8 0.4 2.5 7.0 0.0 2.1 2 0 0 2 2 2 0 Septin DUF2075 PF09848.4 KFX93219.1 - 0.26 10.1 0.0 5.9 5.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.12 KFX93219.1 - 0.29 10.8 2.0 1.4 8.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 G-alpha PF00503.15 KFX93219.1 - 0.55 8.8 0.1 5.3 5.6 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit AAA_28 PF13521.1 KFX93219.1 - 0.86 9.5 2.4 4.8 7.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain DUF3176 PF11374.3 KFX93220.1 - 7.2e-26 90.2 3.0 7.2e-26 90.2 2.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Fungal_trans PF04082.13 KFX93224.1 - 1.1e-18 67.0 0.0 1.8e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX93224.1 - 1.2e-08 34.7 11.8 1.2e-08 34.7 8.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KFX93225.1 - 3.1e-08 33.0 0.0 3.1e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX93225.1 - 0.00012 21.2 0.0 0.00012 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFX93225.1 - 0.0068 15.4 0.0 0.0097 14.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFX93225.1 - 0.017 14.8 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KFX93225.1 - 0.069 12.1 0.0 0.091 11.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like DUF1192 PF06698.6 KFX93225.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) MIP PF00230.15 KFX93226.1 - 3.2e-45 154.3 13.9 4.1e-45 153.9 9.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein AAA_33 PF13671.1 KFX93227.1 - 5.1e-14 52.3 0.0 6.6e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFX93227.1 - 3.6e-10 40.2 0.0 4e-09 36.8 0.0 2.0 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFX93227.1 - 1.4e-09 37.3 0.0 2.8e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 KFX93227.1 - 5.5e-08 33.6 0.0 8.8e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KFX93227.1 - 0.00036 20.5 0.0 0.00039 20.4 0.0 1.3 1 1 0 1 1 1 1 AAA domain CoaE PF01121.15 KFX93227.1 - 0.00049 19.5 0.0 0.00091 18.6 0.0 1.4 1 0 0 1 1 1 1 Dephospho-CoA kinase APS_kinase PF01583.15 KFX93227.1 - 0.0014 18.3 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase SKI PF01202.17 KFX93227.1 - 0.0023 17.7 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase KTI12 PF08433.5 KFX93227.1 - 0.0082 15.3 0.0 0.019 14.1 0.0 1.5 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Viral_helicase1 PF01443.13 KFX93227.1 - 0.02 14.4 0.0 0.33 10.4 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.24 KFX93227.1 - 0.022 14.9 0.0 0.057 13.6 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.1 KFX93227.1 - 0.046 13.6 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase-like family CPT PF07931.7 KFX93227.1 - 0.052 13.1 1.4 2.2 7.8 0.4 2.8 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.1 KFX93227.1 - 0.059 13.3 0.2 0.1 12.5 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain Sigma54_activ_2 PF14532.1 KFX93227.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 KFX93227.1 - 0.14 12.2 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TauD PF02668.11 KFX93228.1 - 6.2e-35 121.1 0.0 8.4e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 KFX93229.1 - 1.2e-14 53.7 28.7 1.2e-14 53.7 19.9 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KFX93229.1 - 1.8e-08 34.0 5.7 4.2e-08 32.8 3.9 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 MASE2 PF05230.6 KFX93230.1 - 0.51 10.3 5.2 2.1 8.3 0.2 2.7 2 0 0 2 2 2 0 MASE2 domain Ribosomal_L2_C PF03947.13 KFX93232.1 - 4.5e-46 155.8 1.4 9.9e-46 154.7 1.0 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KFX93232.1 - 6.3e-26 90.1 0.1 1.4e-25 89.0 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.18 KFX93233.1 - 7.1e-46 154.8 0.1 7e-44 148.4 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 KFX93233.1 - 3.5e-35 120.4 0.0 7.6e-35 119.3 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain PEMT PF04191.8 KFX93234.1 - 1.3e-32 112.0 3.2 2.5e-32 111.1 1.7 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase PH_10 PF15411.1 KFX93239.1 - 1.7e-23 83.0 0.0 1.3e-22 80.1 0.0 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 KFX93239.1 - 3.8e-11 42.8 0.0 8.7e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KFX93239.1 - 5.2e-08 32.8 0.1 9.3e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 KFX93239.1 - 5.9e-08 32.4 4.8 1e-07 31.6 3.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFX93239.1 - 0.00029 20.4 1.4 0.00051 19.6 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX93239.1 - 0.00036 20.2 4.3 0.0006 19.4 3.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain PH PF00169.24 KFX93239.1 - 0.00037 20.6 0.0 0.00086 19.4 0.0 1.6 1 0 0 1 1 1 1 PH domain zf-C3HC4_2 PF13923.1 KFX93239.1 - 0.0012 18.8 4.0 0.0021 18.0 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFX93239.1 - 0.0019 18.2 0.9 0.0038 17.3 0.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFX93239.1 - 0.0055 16.3 3.5 0.0098 15.5 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 KFX93239.1 - 0.76 9.8 3.8 1.5 8.9 2.6 1.5 1 0 0 1 1 1 0 RING-like domain Fungal_trans PF04082.13 KFX93242.1 - 8.3e-36 123.1 0.0 3.3e-35 121.2 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX93242.1 - 8.5e-08 31.9 8.4 1.4e-07 31.2 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAV_VP3 PF04771.7 KFX93242.1 - 0.043 13.7 6.2 0.11 12.4 4.3 1.6 1 0 0 1 1 1 0 Chicken anaemia virus VP-3 protein Anoctamin PF04547.7 KFX93242.1 - 0.12 11.0 2.2 0.18 10.4 1.5 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel PigN PF04987.9 KFX93247.1 - 2.1e-162 540.7 21.9 2.8e-162 540.3 15.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Csm1 PF12539.3 KFX93247.1 - 3.1e-27 94.8 0.1 7.6e-27 93.6 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Phosphodiest PF01663.17 KFX93247.1 - 5.6e-12 45.6 1.0 3.9e-10 39.6 0.1 2.3 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KFX93247.1 - 9.9e-08 31.5 0.0 1.8e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 KFX93247.1 - 0.0084 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily ABC_tran PF00005.22 KFX93249.1 - 2.1e-34 118.7 0.0 4.3e-24 85.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 KFX93249.1 - 1e-28 99.9 21.4 1.5e-26 92.8 5.9 2.4 3 0 0 3 3 2 2 ABC-2 type transporter AAA_21 PF13304.1 KFX93249.1 - 1.2e-16 61.5 0.0 1.7e-05 24.9 0.0 3.4 3 0 0 3 3 3 3 AAA domain SbcCD_C PF13558.1 KFX93249.1 - 3.7e-06 26.7 0.9 0.17 11.7 0.1 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 KFX93249.1 - 2.7e-05 23.5 0.0 0.04 13.1 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KFX93249.1 - 5.1e-05 23.6 0.1 8.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 KFX93249.1 - 0.0008 18.5 0.0 2.9 6.8 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_16 PF13191.1 KFX93249.1 - 0.0014 18.5 0.0 0.004 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFX93249.1 - 0.0018 18.4 0.0 0.0095 16.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFX93249.1 - 0.0025 16.9 0.0 0.0048 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFX93249.1 - 0.0031 17.0 0.1 0.0076 15.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KFX93249.1 - 0.0038 16.6 0.1 0.093 12.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain PDR_assoc PF08370.6 KFX93249.1 - 0.04 13.4 0.0 0.13 11.7 0.0 1.8 1 0 0 1 1 1 0 Plant PDR ABC transporter associated AAA_28 PF13521.1 KFX93249.1 - 0.044 13.7 0.0 0.13 12.2 0.0 1.7 1 1 1 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KFX93249.1 - 0.05 13.3 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 KFX93249.1 - 0.069 12.5 0.2 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 KFX93249.1 - 0.075 13.8 0.0 0.24 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFX93249.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 KFX93249.1 - 0.19 11.9 0.0 0.38 10.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase cobW PF02492.14 KFX93249.1 - 0.19 11.1 0.1 0.31 10.4 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 KFX93249.1 - 0.21 11.3 0.2 2.1 8.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Pribosyltran PF00156.22 KFX93251.1 - 1.6e-17 63.4 0.0 2.2e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KFX93251.1 - 0.02 14.1 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase GST_N PF02798.15 KFX93260.1 - 4.3e-11 42.8 0.3 1.8e-10 40.8 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFX93260.1 - 7.2e-11 41.9 0.2 1.1e-10 41.3 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFX93260.1 - 6.6e-10 39.0 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFX93260.1 - 2.3e-08 33.7 0.0 4.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KFX93260.1 - 6.9e-08 32.3 0.0 1.7e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KFX93260.1 - 2.3e-06 28.0 0.1 3.1e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NOPS PF08075.6 KFX93260.1 - 0.019 15.3 0.1 0.047 14.1 0.1 1.7 1 0 0 1 1 1 0 NOPS (NUC059) domain Spo7 PF03907.8 KFX93261.1 - 2.9e-71 239.4 0.0 3.9e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 Spo7-like protein Abhydrolase_6 PF12697.2 KFX93262.1 - 2.2e-25 89.8 1.1 2.7e-25 89.6 0.1 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX93262.1 - 1.3e-15 57.5 0.0 7.9e-12 45.2 0.0 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX93262.1 - 5.9e-12 45.5 0.0 5.1e-11 42.5 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KFX93262.1 - 1.4e-05 24.6 0.0 2.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.6 KFX93262.1 - 1.5e-05 24.2 0.0 2.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.2 KFX93262.1 - 0.0011 17.8 0.0 0.0024 16.8 0.0 1.5 2 0 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 KFX93262.1 - 0.0061 16.1 0.0 0.098 12.2 0.0 2.6 3 1 0 3 3 3 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KFX93262.1 - 0.023 14.3 0.0 0.066 12.7 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein Thioesterase PF00975.15 KFX93262.1 - 0.031 14.5 0.4 0.098 12.8 0.3 1.8 1 1 0 1 1 1 0 Thioesterase domain Chlorophyllase PF07224.6 KFX93262.1 - 0.032 13.0 0.0 0.046 12.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DUF2305 PF10230.4 KFX93262.1 - 0.1 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_2 PF02230.11 KFX93262.1 - 0.14 11.6 0.0 5.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 KFX93262.1 - 0.16 11.6 0.0 0.36 10.4 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) G-alpha PF00503.15 KFX93263.1 - 5.1e-120 400.7 0.0 6.1e-120 400.4 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFX93263.1 - 8.2e-15 54.4 0.6 6.6e-10 38.5 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFX93263.1 - 0.00043 19.4 0.2 0.55 9.3 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 KFX93263.1 - 0.005 17.3 0.0 0.99 9.9 0.0 2.7 3 0 0 3 3 3 1 Miro-like protein AAA_29 PF13555.1 KFX93263.1 - 0.04 13.4 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phosphorylase PF00343.15 KFX93264.1 - 0 1063.9 0.2 0 1063.7 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase AAA PF00004.24 KFX93267.1 - 6.3e-11 42.5 0.0 1.7e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFX93267.1 - 8.7e-05 21.6 0.0 0.00019 20.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KFX93267.1 - 0.00026 20.7 0.0 0.00058 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KFX93267.1 - 0.00032 20.3 0.0 0.00094 18.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KFX93267.1 - 0.00033 20.8 0.0 0.0011 19.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 KFX93267.1 - 0.0018 17.0 0.0 0.0033 16.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 KFX93267.1 - 0.004 17.0 0.0 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFX93267.1 - 0.0071 17.1 0.2 0.19 12.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.7 KFX93267.1 - 0.025 13.6 0.0 0.069 12.2 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 KFX93267.1 - 0.033 14.0 0.6 0.069 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KFX93267.1 - 0.056 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NTPase_1 PF03266.10 KFX93267.1 - 0.079 12.6 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA_16 PF13191.1 KFX93267.1 - 0.08 12.9 0.1 0.26 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain Fungal_trans PF04082.13 KFX93268.1 - 2.2e-24 85.7 2.7 2.2e-24 85.7 1.8 1.5 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX93268.1 - 2.8e-08 33.5 8.8 5.1e-08 32.6 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fis1_TPR_C PF14853.1 KFX93269.1 - 2e-23 82.0 0.5 4.3e-23 80.9 0.4 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 KFX93269.1 - 5.6e-16 57.5 0.0 1.1e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat zf-RING_2 PF13639.1 KFX93269.1 - 2.1e-15 56.2 13.7 3.1e-15 55.7 4.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFX93269.1 - 3.9e-11 42.4 8.5 9e-10 38.0 2.1 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFX93269.1 - 4e-08 33.1 12.6 6.6e-08 32.4 4.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFX93269.1 - 9.6e-08 32.0 7.2 3.5e-07 30.2 1.9 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KFX93269.1 - 3.7e-07 29.7 3.6 3.7e-07 29.7 2.5 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFX93269.1 - 4.8e-06 26.1 14.4 2e-05 24.1 3.6 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) HypA PF01155.14 KFX93269.1 - 0.00023 20.7 0.2 0.00023 20.7 0.1 2.2 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family zf-RING_3 PF14369.1 KFX93269.1 - 0.0014 18.5 3.3 0.0014 18.5 2.3 2.5 2 0 0 2 2 2 1 zinc-finger DUF1272 PF06906.6 KFX93269.1 - 0.0028 17.4 5.5 0.22 11.3 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1272) zf-Apc11 PF12861.2 KFX93269.1 - 0.0049 16.6 1.6 0.0049 16.6 1.1 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_2 PF07719.12 KFX93269.1 - 0.011 15.6 0.6 0.029 14.2 0.4 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Prok-RING_4 PF14447.1 KFX93269.1 - 0.047 13.2 2.7 0.12 11.9 1.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.1 KFX93269.1 - 0.6 9.8 12.9 3.2 7.5 0.5 2.8 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 Baculo_RING PF05883.6 KFX93269.1 - 1.5 8.6 5.3 0.32 10.8 0.8 1.8 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zf-C3HC4_4 PF15227.1 KFX93269.1 - 2 8.3 12.9 4.6 7.2 0.6 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 KFX93269.1 - 5.5 7.1 14.4 0.76 9.8 5.1 2.4 2 0 0 2 2 2 0 RING-variant domain DZR PF12773.2 KFX93269.1 - 5.7 6.8 6.1 2.6 7.9 0.1 2.5 2 1 0 2 2 2 0 Double zinc ribbon PHD PF00628.24 KFX93269.1 - 9.7 5.9 16.7 0.46 10.2 4.1 2.6 2 1 0 2 2 2 0 PHD-finger Spc24 PF08286.6 KFX93270.1 - 8e-35 119.0 4.4 2e-33 114.5 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.15 KFX93270.1 - 0.00014 21.6 3.2 0.18 11.5 0.1 2.3 2 0 0 2 2 2 2 Prefoldin subunit TPR_MLP1_2 PF07926.7 KFX93270.1 - 0.0024 17.5 8.0 0.0035 17.0 5.6 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 KFX93270.1 - 0.019 14.1 3.0 0.022 13.9 2.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 KFX93270.1 - 0.023 14.5 3.4 3.9 7.4 0.3 2.7 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) DUF342 PF03961.8 KFX93270.1 - 0.044 12.2 2.7 0.055 11.8 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Streptin-Immun PF11083.3 KFX93270.1 - 0.05 13.6 2.1 0.079 12.9 0.4 1.9 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein APG6 PF04111.7 KFX93270.1 - 0.055 12.5 5.6 0.071 12.1 3.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Exonuc_VII_L PF02601.10 KFX93270.1 - 0.13 11.3 4.0 0.16 11.1 2.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Troponin PF00992.15 KFX93270.1 - 0.18 11.9 3.0 0.21 11.6 1.5 1.5 1 1 0 1 1 1 0 Troponin Laminin_II PF06009.7 KFX93270.1 - 0.18 11.5 5.6 0.24 11.1 3.5 1.5 1 1 0 1 1 1 0 Laminin Domain II DUF948 PF06103.6 KFX93270.1 - 0.39 10.6 4.7 4.3 7.2 0.5 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Occludin_ELL PF07303.8 KFX93270.1 - 0.39 11.4 2.8 1.1 10.0 1.6 2.0 1 1 1 2 2 2 0 Occludin homology domain Lipoprotein_16 PF03923.8 KFX93270.1 - 0.41 9.9 4.7 0.12 11.7 1.1 1.6 2 0 0 2 2 2 0 Uncharacterized lipoprotein Noelin-1 PF12308.3 KFX93270.1 - 0.64 9.8 2.9 0.68 9.7 0.6 2.0 2 0 0 2 2 2 0 Neurogenesis glycoprotein Syntaxin-6_N PF09177.6 KFX93270.1 - 0.8 10.1 8.3 1.4 9.3 1.2 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal TBPIP PF07106.8 KFX93270.1 - 0.82 9.1 8.4 3.2 7.2 0.4 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Syntaxin PF00804.20 KFX93270.1 - 1 9.5 7.7 0.99 9.6 4.1 1.8 1 1 1 2 2 2 0 Syntaxin Viral_P18 PF04521.8 KFX93270.1 - 1.3 8.5 9.6 0.79 9.1 2.2 2.2 1 1 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Cep57_MT_bd PF06657.8 KFX93270.1 - 4.9 7.1 9.2 1.3 9.0 1.1 2.4 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 PCRF PF03462.13 KFX93270.1 - 5.1 6.8 5.7 5.1 6.8 0.6 2.3 1 1 1 2 2 2 0 PCRF domain FlxA PF14282.1 KFX93270.1 - 6.1 6.8 10.8 3.4 7.6 2.1 2.3 1 1 1 2 2 2 0 FlxA-like protein Avl9 PF09794.4 KFX93273.1 - 4.5e-146 486.1 0.0 6.4e-146 485.6 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 End3 PF12761.2 KFX93273.1 - 8.1e-75 250.7 0.4 1.5e-74 249.9 0.2 1.5 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 KFX93273.1 - 2.1e-51 172.0 0.0 2e-49 165.6 0.0 2.5 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF2347 PF09804.4 KFX93273.1 - 2.1e-07 30.4 0.1 2.5e-06 26.9 0.1 2.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) EF-hand_8 PF13833.1 KFX93273.1 - 2.2e-07 30.3 1.3 2e-06 27.3 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 KFX93273.1 - 2.3e-07 29.6 1.8 1.5e-06 27.1 0.2 2.8 3 0 0 3 3 3 1 EF hand SPA PF08616.5 KFX93273.1 - 1.7e-06 27.7 0.0 0.0016 18.1 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis EF-hand_7 PF13499.1 KFX93273.1 - 2.8e-05 24.1 0.1 0.00031 20.8 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 KFX93273.1 - 0.00016 21.2 0.6 0.0035 17.0 0.2 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 KFX93273.1 - 0.012 14.9 0.1 0.044 13.1 0.1 2.0 1 0 0 1 1 1 0 EF hand Atg14 PF10186.4 KFX93273.1 - 6.6 5.5 9.3 0.44 9.4 2.8 1.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Zn_clus PF00172.13 KFX93274.1 - 1e-06 28.5 11.5 1e-06 28.5 7.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX93274.1 - 0.00014 20.8 0.0 0.00033 19.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMN_red PF03358.10 KFX93275.1 - 9.7e-25 86.8 0.0 1.5e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KFX93275.1 - 3.8e-07 29.8 0.0 4.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold HK PF02110.10 KFX93277.1 - 4.6e-76 255.2 0.4 6.8e-76 254.6 0.3 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 KFX93277.1 - 5.3e-56 188.5 1.4 9.5e-56 187.7 1.0 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Carb_kinase PF01256.12 KFX93277.1 - 3.5e-06 26.4 0.3 1.6e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 KFX93277.1 - 0.0025 17.0 0.9 0.039 13.1 0.0 2.7 2 1 0 2 2 2 1 Phosphomethylpyrimidine kinase Peripla_BP_6 PF13458.1 KFX93277.1 - 0.0038 16.6 0.4 0.56 9.4 0.0 3.3 3 1 1 4 4 4 1 Periplasmic binding protein chaperone_DMP PF10448.4 KFX93277.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 20S proteasome chaperone eIF-5_eIF-2B PF01873.12 KFX93278.1 - 4.7e-39 132.9 0.0 7.1e-39 132.3 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 KFX93278.1 - 1.1e-25 89.3 0.0 3.1e-25 87.9 0.0 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon DUF1387 PF07139.6 KFX93278.1 - 0.0048 16.5 7.3 0.0092 15.6 5.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1387) DUF1754 PF08555.5 KFX93278.1 - 2 9.0 10.5 0.3 11.7 3.8 2.2 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) HEAT_2 PF13646.1 KFX93279.1 - 8e-09 35.6 1.8 0.14 12.4 0.0 5.1 4 0 0 4 4 4 3 HEAT repeats HEAT PF02985.17 KFX93279.1 - 4.1e-06 26.4 0.1 0.42 10.8 0.0 4.6 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.1 KFX93279.1 - 0.033 14.6 1.6 14 6.3 0.0 5.0 4 1 1 5 5 5 0 HEAT-like repeat Arm PF00514.18 KFX93279.1 - 0.058 13.2 1.5 0.83 9.5 0.0 3.3 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat SRPRB PF09439.5 KFX93280.1 - 7.2e-33 113.3 0.1 5.1e-32 110.5 0.1 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KFX93280.1 - 1.5e-07 30.8 0.0 4.7e-07 29.1 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFX93280.1 - 3.4e-07 29.8 0.0 9.4e-07 28.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFX93280.1 - 3.6e-06 26.9 0.0 6.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KFX93280.1 - 2.4e-05 24.4 0.6 0.00029 20.8 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain Arf PF00025.16 KFX93280.1 - 3.5e-05 23.1 0.0 0.00097 18.4 0.0 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_22 PF13401.1 KFX93280.1 - 0.0059 16.7 0.0 0.011 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFX93280.1 - 0.0061 15.6 0.1 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin cobW PF02492.14 KFX93280.1 - 0.0089 15.4 0.3 2.1 7.7 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 KFX93280.1 - 0.014 15.1 0.1 0.26 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 KFX93280.1 - 0.017 14.5 0.0 5.9 6.2 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 KFX93280.1 - 0.027 13.9 0.0 0.43 10.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 KFX93280.1 - 0.035 13.6 0.2 0.088 12.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KFX93280.1 - 0.036 14.3 0.0 0.23 11.7 0.0 2.1 2 1 0 2 2 2 0 ABC transporter Septin PF00735.13 KFX93280.1 - 0.039 12.9 0.0 0.078 11.9 0.0 1.4 1 0 0 1 1 1 0 Septin DUF258 PF03193.11 KFX93280.1 - 0.04 13.0 0.2 0.25 10.5 0.1 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 KFX93280.1 - 0.063 13.4 1.3 0.64 10.2 0.9 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ras PF00071.17 KFX93280.1 - 0.084 12.2 0.1 4.4 6.6 0.0 2.4 2 1 0 2 2 2 0 Ras family ATP_bind_1 PF03029.12 KFX93280.1 - 0.1 12.1 0.1 5.7 6.3 0.0 2.4 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Miro PF08477.8 KFX93280.1 - 0.12 12.8 0.0 0.36 11.3 0.0 1.9 1 1 0 1 1 1 0 Miro-like protein zf-DHHC PF01529.15 KFX93281.1 - 1.3e-38 132.1 9.2 1.3e-38 132.1 6.4 2.3 3 0 0 3 3 3 1 DHHC palmitoyltransferase Ank_2 PF12796.2 KFX93281.1 - 4.2e-32 110.3 0.0 1.2e-17 64.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFX93281.1 - 9.6e-32 107.2 4.5 1.8e-09 36.9 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 KFX93281.1 - 6.5e-24 83.8 0.9 3.3e-06 27.4 0.0 4.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX93281.1 - 5.3e-23 80.5 2.3 5.3e-07 29.6 0.1 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX93281.1 - 5.4e-21 72.5 1.1 2.2e-08 33.5 0.0 6.1 5 0 0 5 5 5 3 Ankyrin repeat DUF1401 PF07180.6 KFX93281.1 - 0.2 11.4 0.1 0.45 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1401) Kinesin PF00225.18 KFX93282.1 - 6.1e-110 367.0 1.7 7.3e-110 366.7 0.0 2.0 3 0 0 3 3 3 1 Kinesin motor domain DUF3694 PF12473.3 KFX93282.1 - 6.4e-39 132.8 0.1 1.4e-38 131.6 0.1 1.7 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 KFX93282.1 - 1.1e-06 28.7 0.0 3.8e-06 27.0 0.0 2.0 1 0 0 1 1 1 1 PH domain KIF1B PF12423.3 KFX93282.1 - 7.9e-06 25.8 0.5 2e-05 24.4 0.4 1.8 1 0 0 1 1 1 1 Kinesin protein 1B DinI PF06183.8 KFX93282.1 - 0.12 12.3 5.3 0.56 10.2 3.7 2.2 1 0 0 1 1 1 0 DinI-like family WW PF00397.21 KFX93286.1 - 4.2e-07 29.7 1.5 4.2e-07 29.7 1.0 2.0 2 0 0 2 2 2 1 WW domain Voldacs PF03517.8 KFX93287.1 - 7e-28 97.1 0.0 7e-28 97.1 0.0 1.8 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling MIF4G_like PF09088.6 KFX93287.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 MIF4G like Zn_clus PF00172.13 KFX93309.1 - 4.5e-07 29.6 5.6 7.9e-07 28.8 3.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Baculo_PEP_C PF04513.7 KFX93309.1 - 0.043 13.6 0.6 0.076 12.8 0.1 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AMP-binding PF00501.23 KFX93310.1 - 2.1e-78 263.5 0.0 3.5e-78 262.8 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 KFX93310.1 - 1.8e-74 250.4 0.0 4e-74 249.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.15 KFX93310.1 - 3.1e-54 183.8 0.2 6.4e-54 182.8 0.1 1.5 1 0 0 1 1 1 1 Condensation domain KR PF08659.5 KFX93310.1 - 1.4e-53 181.3 0.1 9.3e-51 172.0 0.0 3.9 4 0 0 4 4 4 1 KR domain Acyl_transf_1 PF00698.16 KFX93310.1 - 5.5e-52 177.0 0.3 1.2e-51 175.9 0.2 1.5 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 KFX93310.1 - 1.2e-45 155.3 0.7 9.6e-42 142.7 0.0 4.1 4 0 0 4 4 4 2 short chain dehydrogenase PS-DH PF14765.1 KFX93310.1 - 9.2e-43 146.4 0.0 2e-42 145.3 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase NAD_binding_4 PF07993.7 KFX93310.1 - 6.5e-33 113.6 0.0 6e-31 107.2 0.0 2.8 2 1 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 KFX93310.1 - 4.3e-32 110.4 0.2 2.8e-31 107.8 0.0 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KFX93310.1 - 3e-20 72.2 0.8 2.8e-11 43.5 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 KFX93310.1 - 1e-18 67.5 0.0 5e-18 65.4 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 KFX93310.1 - 2.2e-17 63.2 0.0 3.2e-12 46.3 0.0 3.0 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.1 KFX93310.1 - 6.2e-13 48.7 0.0 1.5e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX93310.1 - 2e-12 47.4 0.0 7.7e-12 45.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 KFX93310.1 - 1.3e-09 37.1 0.0 9.3e-06 24.5 0.0 2.4 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_18 PF12847.2 KFX93310.1 - 3.4e-09 37.2 0.0 5.5e-07 30.1 0.0 3.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX93310.1 - 6.1e-09 35.6 0.0 1.6e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX93310.1 - 1.8e-07 30.5 0.1 8.6e-07 28.3 0.0 2.2 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family HxxPF_rpt PF13745.1 KFX93310.1 - 3.8e-07 30.3 0.1 1.4e-06 28.4 0.1 2.0 1 0 0 1 1 1 1 HxxPF-repeated domain Thiolase_N PF00108.18 KFX93310.1 - 1.5e-05 24.0 0.0 4e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain DapB_N PF01113.15 KFX93310.1 - 0.00033 20.5 0.7 0.18 11.7 0.0 3.4 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 KFX93310.1 - 0.015 14.2 0.0 5.1 5.9 0.0 2.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Methyltransf_16 PF10294.4 KFX93310.1 - 0.027 13.9 0.0 0.1 12.0 0.0 1.9 1 0 0 1 1 1 0 Putative methyltransferase DREV PF05219.7 KFX93310.1 - 0.058 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Ribosomal_60s PF00428.14 KFX93310.1 - 1.2 9.5 7.5 0.28 11.5 0.8 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Abhydrolase_6 PF12697.2 KFX93322.1 - 3.5e-22 79.4 0.0 6.5e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX93322.1 - 6.4e-15 55.3 0.0 1.2e-13 51.1 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 KFX93322.1 - 1.2e-09 37.1 0.0 1.7e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.2 KFX93322.1 - 2.6e-06 27.2 0.1 3.7e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KFX93322.1 - 0.00044 19.7 0.0 0.00069 19.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF221 PF02714.10 KFX93323.1 - 5.4e-98 327.8 13.2 5.4e-98 327.8 9.2 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KFX93323.1 - 1.7e-38 131.6 2.2 1.7e-38 131.6 1.5 2.1 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KFX93323.1 - 8.2e-21 73.6 0.1 2e-20 72.4 0.1 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KFX93323.1 - 2.8e-08 34.1 0.0 0.00014 22.3 0.0 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF4463) RRM_5 PF13893.1 KFX93323.1 - 0.062 13.1 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFX93323.1 - 0.08 12.5 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CCDC50_N PF15295.1 KFX93323.1 - 0.18 11.7 0.5 0.31 10.9 0.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus DUF4243 PF14027.1 KFX93324.1 - 3.2e-99 332.5 0.9 3.8e-99 332.2 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) HSP33 PF01430.14 KFX93324.1 - 0.0026 16.9 0.0 0.0049 16.0 0.0 1.4 1 0 0 1 1 1 1 Hsp33 protein DUF3848 PF12959.2 KFX93324.1 - 0.1 12.5 0.0 0.32 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) Fungal_trans PF04082.13 KFX93327.1 - 9.5e-29 100.0 0.1 1.5e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX93327.1 - 2.8e-11 43.1 12.2 5e-11 42.3 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BicD PF09730.4 KFX93331.1 - 0.0048 15.3 1.1 0.0056 15.1 0.7 1.0 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D bZIP_1 PF00170.16 KFX93331.1 - 0.056 13.3 1.7 0.1 12.5 1.2 1.5 1 0 0 1 1 1 0 bZIP transcription factor Dynamin_M PF01031.15 KFX93332.1 - 2.2e-30 105.4 0.3 1.3e-28 99.6 0.2 2.3 1 1 0 1 1 1 1 Dynamin central region HATPase_c PF02518.21 KFX93332.1 - 7.3e-21 73.9 0.2 1.5e-20 72.9 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KFX93332.1 - 1.3e-11 44.3 0.3 1.3e-10 41.1 0.0 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 KFX93332.1 - 0.0051 16.9 0.1 0.023 14.8 0.0 2.2 2 0 0 2 2 2 1 GAF domain Dynamin_N PF00350.18 KFX93332.1 - 0.089 12.6 0.1 0.39 10.5 0.0 2.2 2 0 0 2 2 2 0 Dynamin family GED PF02212.13 KFX93332.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Dynamin GTPase effector domain HATPase_c PF02518.21 KFX93333.1 - 7.1e-26 90.1 0.0 1.2e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KFX93333.1 - 3.5e-10 39.7 0.0 1.5e-09 37.7 0.0 2.1 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 KFX93333.1 - 9.4e-06 25.6 0.3 0.00026 20.9 0.2 2.4 1 1 0 1 1 1 1 Response regulator receiver domain MEDS PF14417.1 KFX93333.1 - 0.00025 20.1 0.1 0.27 10.2 0.0 2.6 2 0 0 2 2 2 2 MEDS: MEthanogen/methylotroph, DcmR Sensory domain DUF4141 PF13605.1 KFX93333.1 - 0.0003 19.9 0.2 0.00083 18.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4141) HATPase_c_3 PF13589.1 KFX93333.1 - 0.055 13.1 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Hemerythrin PF01814.18 KFX93334.1 - 2.4e-08 34.2 0.0 4.8e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain CBM_21 PF03370.8 KFX93335.1 - 2.4e-30 104.8 0.3 4.4e-30 103.9 0.2 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit bZIP_1 PF00170.16 KFX93336.1 - 5.6e-08 32.6 7.2 5.6e-08 32.6 5.0 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KFX93336.1 - 2e-05 24.3 7.1 2e-05 24.3 4.9 2.3 2 0 0 2 2 2 1 Basic region leucine zipper YlqD PF11068.3 KFX93336.1 - 1.2 9.2 8.6 1.7 8.6 1.5 2.2 2 0 0 2 2 2 0 YlqD protein Hemerythrin PF01814.18 KFX93337.1 - 1.9e-12 47.5 0.1 2.6e-12 47.0 0.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain POR PF01558.13 KFX93337.1 - 0.014 15.3 0.0 0.024 14.5 0.0 1.5 1 1 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase PH PF00169.24 KFX93338.1 - 3.3e-07 30.4 0.2 6e-07 29.6 0.2 1.4 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 KFX93338.1 - 0.089 13.0 1.2 0.67 10.2 0.8 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain PH_9 PF15410.1 KFX93338.1 - 0.1 12.7 0.2 0.19 11.9 0.1 1.6 1 1 0 1 1 1 0 Pleckstrin homology domain Myb_DNA-bind_3 PF12776.2 KFX93339.1 - 2.2 8.9 11.7 2.8 8.6 0.1 3.5 2 1 1 3 3 3 0 Myb/SANT-like DNA-binding domain RRM_6 PF14259.1 KFX93340.1 - 0.05 13.5 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFX93340.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAT1 PF09770.4 KFX93340.1 - 6.5 4.8 10.9 8.1 4.5 7.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 bZIP_1 PF00170.16 KFX93342.1 - 1.5e-08 34.4 7.5 2.9e-08 33.5 5.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFX93342.1 - 0.00083 19.1 8.6 0.0018 18.0 6.0 1.6 1 0 0 1 1 1 1 Basic region leucine zipper K_channel_TID PF07941.6 KFX93342.1 - 0.073 13.2 2.4 0.19 11.9 1.7 1.7 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain bZIP_Maf PF03131.12 KFX93342.1 - 0.093 13.0 12.8 0.059 13.6 6.4 2.1 1 1 1 2 2 2 0 bZIP Maf transcription factor Med3 PF11593.3 KFX93342.1 - 0.24 10.6 8.4 0.4 9.8 5.8 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.8 KFX93342.1 - 0.28 11.0 5.0 0.35 10.7 3.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2823 PF11034.3 KFX93343.1 - 7.9e-29 99.5 13.5 8.8e-29 99.4 9.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) HSP9_HSP12 PF04119.7 KFX93343.1 - 1.8 8.6 8.4 5.8 7.0 4.0 2.1 1 1 1 2 2 2 0 Heat shock protein 9/12 Hemerythrin PF01814.18 KFX93344.1 - 5e-11 42.8 0.1 8.1e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Pkinase PF00069.20 KFX93345.1 - 1.5e-38 132.4 0.0 1.8e-38 132.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX93345.1 - 9.6e-16 57.6 0.0 1.2e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFX93345.1 - 2.8e-06 27.2 0.3 0.0061 16.3 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family HATPase_c PF02518.21 KFX93346.1 - 7.3e-22 77.1 0.2 1.9e-21 75.8 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KFX93346.1 - 4.3e-18 65.3 0.0 1.9e-17 63.2 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KFX93346.1 - 9.7e-10 38.3 0.1 3e-09 36.7 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 KFX93346.1 - 0.0026 17.8 0.1 0.013 15.6 0.0 2.2 2 0 0 2 2 2 1 GAF domain Aldedh PF00171.17 KFX93374.1 - 3.1e-30 104.9 0.0 3.7e-30 104.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family JmjN PF02375.12 KFX93381.1 - 1.2e-05 24.7 0.6 2.3e-05 23.7 0.4 1.5 1 0 0 1 1 1 1 jmjN domain DUF2617 PF10936.3 KFX93383.1 - 0.026 14.0 0.9 0.051 13.1 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF2617 DUF4404 PF14357.1 KFX93383.1 - 0.22 11.9 5.8 0.91 9.9 4.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) CBFD_NFYB_HMF PF00808.18 KFX93384.1 - 0.00014 21.8 0.0 0.00018 21.4 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.1 KFX93384.1 - 0.029 14.3 0.4 0.09 12.7 0.3 1.7 1 1 0 1 1 1 0 Centromere kinetochore component W PS_Dcarbxylase PF02666.10 KFX93386.1 - 2e-51 174.2 0.0 3.2e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 KFX93386.1 - 1.7e-33 114.3 0.1 1.6e-16 59.8 0.0 2.6 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 KFX93386.1 - 1.4e-05 25.1 0.2 8.9e-05 22.5 0.1 2.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KFX93386.1 - 0.0036 16.4 0.0 0.02 14.1 0.0 2.4 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KFX93386.1 - 0.0069 16.1 0.0 0.073 12.9 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain PAP2 PF01569.16 KFX93387.1 - 5.1e-09 35.8 19.1 6.8e-08 32.2 13.2 2.7 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 KFX93387.1 - 7.3e-06 25.6 8.4 7.3e-06 25.6 5.8 2.4 1 1 1 2 2 2 1 PAP2 superfamily Luteo_P1-P2 PF08467.5 KFX93387.1 - 0.1 11.3 0.5 0.16 10.7 0.4 1.1 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase PAP2_C PF14360.1 KFX93387.1 - 3.4 8.0 14.3 1.2 9.4 2.7 3.3 3 0 0 3 3 3 0 PAP2 superfamily C-terminal NAD_binding_8 PF13450.1 KFX93388.1 - 2.7e-07 30.4 1.5 5.8e-07 29.4 1.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFX93388.1 - 0.00033 20.5 1.4 0.0067 16.3 0.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KFX93388.1 - 0.0013 17.9 0.2 0.0017 17.4 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KFX93388.1 - 0.0016 17.5 3.6 0.011 14.8 2.5 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFX93388.1 - 0.0018 17.2 6.1 0.0025 16.8 3.4 1.6 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFX93388.1 - 0.0022 18.3 1.0 0.0056 17.0 0.7 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFX93388.1 - 0.0056 15.5 5.0 0.045 12.6 1.6 2.1 1 1 1 2 2 2 1 FAD binding domain GIDA PF01134.17 KFX93388.1 - 0.031 13.1 1.6 0.049 12.4 1.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KFX93388.1 - 0.2 11.7 1.4 0.36 10.8 0.9 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFX93388.1 - 0.27 9.6 2.1 0.49 8.7 1.5 1.4 1 0 0 1 1 1 0 HI0933-like protein MFS_1 PF07690.11 KFX93392.1 - 7.9e-16 57.6 38.8 1.8e-13 49.9 26.4 3.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KFX93392.1 - 0.48 8.5 23.7 0.47 8.5 13.2 2.8 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.20 KFX93393.1 - 4.5e-16 59.2 0.1 7.8e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX93393.1 - 6.3e-09 35.7 0.1 1.2e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Fungal_trans_2 PF11951.3 KFX93394.1 - 4e-07 28.9 3.2 0.00029 19.5 0.1 2.3 2 1 0 2 2 2 2 Fungal specific transcription factor domain Aldedh PF00171.17 KFX93395.1 - 4.9e-79 265.8 0.0 6.3e-79 265.4 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family IF-2B PF01008.12 KFX93396.1 - 2e-19 69.6 0.1 4.6e-19 68.4 0.1 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.23 KFX93396.1 - 1.5e-11 44.0 0.0 2.5e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Sugar_tr PF00083.19 KFX93397.1 - 3.7e-91 305.9 26.9 4.5e-91 305.6 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX93397.1 - 8.6e-16 57.5 48.3 2.9e-11 42.6 23.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3278 PF11683.3 KFX93397.1 - 0.051 13.5 0.5 0.051 13.5 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) DUF3328 PF11807.3 KFX93405.1 - 3.2e-40 138.1 0.0 4.1e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Acetyltransf_3 PF13302.1 KFX93406.1 - 9.2e-24 84.2 0.0 1.1e-23 83.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX93406.1 - 1.8e-08 34.2 0.0 1.1e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KFX93406.1 - 0.00018 21.4 0.0 0.00025 20.9 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFX93406.1 - 0.0019 17.9 0.1 0.012 15.2 0.0 2.0 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.1 KFX93406.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1918 PF08940.6 KFX93408.1 - 0.094 12.0 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Dimer_Tnp_hAT PF05699.9 KFX93411.1 - 3.4e-17 61.8 0.0 1.1e-16 60.1 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 KFX93411.1 - 0.0025 17.7 0.0 0.0077 16.1 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) PHP PF02811.14 KFX93413.1 - 0.078 12.7 0.0 0.079 12.7 0.0 1.1 1 0 0 1 1 1 0 PHP domain NAD_kinase PF01513.16 KFX93440.1 - 7.1e-71 238.2 0.0 2e-70 236.8 0.0 1.6 1 1 0 1 1 1 1 ATP-NAD kinase Cupin_3 PF05899.7 KFX93440.1 - 0.04 13.2 0.0 2.2 7.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF861) IF-2B PF01008.12 KFX93441.1 - 1.7e-78 263.4 0.0 2.4e-78 263.0 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Lactamase_B PF00753.22 KFX93441.1 - 8.2e-26 90.8 3.7 2.1e-25 89.5 2.5 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFX93441.1 - 0.00036 20.1 0.1 0.00069 19.2 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain COMPASS-Shg1 PF05205.7 KFX93443.1 - 2.3e-24 85.7 0.6 5.2e-24 84.5 0.4 1.6 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 PRCH PF03967.8 KFX93443.1 - 0.11 12.1 0.2 0.3 10.6 0.1 1.7 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region UCH PF00443.24 KFX93444.1 - 5e-42 143.8 0.0 8e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFX93444.1 - 3.8e-10 39.7 0.0 7.3e-10 38.7 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Alb1 PF09135.6 KFX93445.1 - 6.2e-18 65.4 16.3 9.4e-18 64.8 11.3 1.3 1 0 0 1 1 1 1 Alb1 Las1 PF04031.8 KFX93446.1 - 1.1e-53 181.0 0.0 1.7e-53 180.4 0.0 1.3 1 0 0 1 1 1 1 Las1-like EF-hand_8 PF13833.1 KFX93446.1 - 0.081 12.5 0.0 25 4.5 0.1 3.1 3 0 0 3 3 3 0 EF-hand domain pair IF4E PF01652.13 KFX93447.1 - 6.1e-38 129.9 0.1 7.5e-38 129.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF4598 PF15370.1 KFX93448.1 - 2.1e-14 53.7 7.2 2.1e-14 53.7 5.0 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) Treacle PF03546.9 KFX93448.1 - 3.9 6.1 9.3 0.58 8.8 0.5 2.1 2 0 0 2 2 2 0 Treacher Collins syndrome protein Treacle GTP_EFTU PF00009.22 KFX93449.1 - 5.8e-59 198.6 0.1 8e-59 198.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KFX93449.1 - 4.4e-27 94.1 0.1 2.9e-26 91.5 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFX93449.1 - 1.3e-19 70.0 1.7 3.5e-19 68.6 1.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFX93449.1 - 8.7e-06 25.6 0.0 1.6e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFX93449.1 - 0.0002 21.8 0.0 0.00035 21.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D4 PF14578.1 KFX93449.1 - 0.0025 17.3 0.1 0.0061 16.1 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 PduV-EutP PF10662.4 KFX93449.1 - 0.036 13.5 0.3 4 6.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IF3_C PF00707.17 KFX93450.1 - 1.2e-13 50.6 0.2 5.1e-13 48.5 0.1 2.0 1 1 1 2 2 2 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 KFX93450.1 - 0.00051 19.4 0.2 0.0012 18.2 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial translation initiation factor Peptidase_S24 PF00717.18 KFX93451.1 - 4e-11 42.4 0.5 6.4e-11 41.7 0.3 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 KFX93451.1 - 8.3e-05 22.1 0.0 0.0024 17.4 0.0 2.3 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Arm PF00514.18 KFX93452.1 - 7e-68 222.3 33.6 5.9e-13 48.1 0.1 11.2 11 1 1 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFX93452.1 - 2.1e-22 79.2 16.2 1.8e-05 24.9 0.2 7.5 1 1 5 7 7 7 6 HEAT repeats HEAT PF02985.17 KFX93452.1 - 1.6e-19 68.1 15.8 0.022 14.8 0.1 9.5 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.1 KFX93452.1 - 2e-15 56.7 15.5 0.0014 19.0 0.1 7.9 5 3 4 9 9 9 6 HEAT-like repeat Adaptin_N PF01602.15 KFX93452.1 - 1.2e-12 46.9 9.1 2.8e-08 32.5 0.3 2.9 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.8 KFX93452.1 - 1.2e-10 40.9 8.5 0.0067 15.5 0.0 3.6 2 1 1 3 3 3 3 Armadillo-like V-ATPase_H_N PF03224.9 KFX93452.1 - 2.8e-10 39.8 3.3 0.0003 20.0 0.4 3.8 2 1 1 3 3 3 2 V-ATPase subunit H KAP PF05804.7 KFX93452.1 - 1.5e-09 36.3 0.6 3.4e-09 35.2 0.2 1.6 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_C PF11698.3 KFX93452.1 - 0.00071 19.4 3.0 2.9 7.8 0.1 4.5 1 1 5 6 6 6 1 V-ATPase subunit H HEAT_PBS PF03130.11 KFX93452.1 - 0.00071 19.8 6.7 2.3 8.9 0.4 6.7 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat DUF2454 PF10521.4 KFX93452.1 - 0.0028 16.7 0.1 0.0068 15.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) Vac14_Fab1_bd PF12755.2 KFX93452.1 - 0.021 15.2 0.2 1 9.7 0.1 3.5 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 KFX93452.1 - 0.025 14.2 0.6 0.47 10.1 0.2 2.8 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis Vpu PF00558.14 KFX93452.1 - 0.18 11.3 2.0 0.27 10.8 0.3 2.1 2 0 0 2 2 2 0 Vpu protein Atx10homo_assoc PF09759.4 KFX93452.1 - 3.7 7.3 6.4 8 6.2 0.0 3.7 5 0 0 5 5 5 0 Spinocerebellar ataxia type 10 protein domain CBS PF00571.23 KFX93453.1 - 1.4e-29 101.5 9.6 1.3e-13 50.5 0.1 4.3 4 0 0 4 4 4 4 CBS domain HAD_2 PF13419.1 KFX93463.1 - 1.4e-15 57.9 0.0 2.5e-15 57.1 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFX93463.1 - 2e-08 34.8 0.0 6.8e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFX93463.1 - 7.8e-06 25.5 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NT5C PF06941.7 KFX93463.1 - 0.013 14.9 0.0 0.066 12.7 0.0 1.9 1 1 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) TPR_11 PF13414.1 KFX93464.1 - 4e-09 35.9 4.1 7.6e-09 35.0 1.7 2.1 2 0 0 2 2 2 1 TPR repeat Lipoprotein_5 PF01298.13 KFX93464.1 - 0.00059 18.9 0.8 0.00088 18.3 0.6 1.2 1 0 0 1 1 1 1 Transferrin binding protein-like solute binding protein TPR_14 PF13428.1 KFX93464.1 - 0.0048 17.4 0.6 0.059 14.0 0.0 2.9 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFX93464.1 - 0.015 15.6 0.1 0.04 14.2 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFX93464.1 - 0.015 15.1 2.8 0.1 12.5 0.5 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KFX93464.1 - 0.038 14.1 0.4 0.076 13.1 0.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KFX93464.1 - 0.19 11.3 5.7 0.37 10.4 0.4 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat Vfa1 PF08432.5 KFX93464.1 - 2.7 8.0 6.8 0.28 11.1 1.5 1.8 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF4407 PF14362.1 KFX93464.1 - 3 6.7 7.8 4.1 6.2 5.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Acyltransferase PF01553.16 KFX93465.1 - 1.1e-15 57.1 0.0 2.6e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase UPF0086 PF01868.11 KFX93466.1 - 3.3e-21 74.7 0.1 5.3e-21 74.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 MAP1B_neuraxin PF00414.12 KFX93467.1 - 0.035 13.4 0.1 0.1 11.9 0.1 1.9 1 0 0 1 1 1 0 Neuraxin and MAP1B repeat NMD3 PF04981.8 KFX93468.1 - 2.2e-71 239.7 1.7 4e-71 238.8 1.2 1.4 1 0 0 1 1 1 1 NMD3 family DZR PF12773.2 KFX93468.1 - 5.9 6.7 11.1 19 5.1 3.9 2.7 2 1 0 2 2 2 0 Double zinc ribbon RRM_6 PF14259.1 KFX93469.1 - 6.9e-10 38.7 0.0 1.9e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFX93469.1 - 2.6e-09 36.5 0.0 8.9e-07 28.4 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX93469.1 - 2.6e-05 23.9 0.0 0.00054 19.7 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAR2 PF05282.6 KFX93469.1 - 0.4 9.5 5.0 0.078 11.8 1.0 1.5 2 0 0 2 2 2 0 AAR2 protein F-box PF00646.28 KFX93471.1 - 5e-07 29.2 0.1 9.6e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFX93471.1 - 1.6e-05 24.4 0.0 4.3e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like DUF3328 PF11807.3 KFX93472.1 - 4.6e-27 95.1 0.0 8.7e-27 94.2 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Acetyltransf_1 PF00583.19 KFX93473.1 - 0.01 15.8 0.0 0.038 14.0 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFX93473.1 - 0.022 14.8 0.2 0.95 9.5 0.0 2.7 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF664 PF04978.7 KFX93473.1 - 0.075 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF664) Acetyltransf_7 PF13508.1 KFX93473.1 - 0.097 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PIG-P PF08510.7 KFX93474.1 - 6.3e-42 142.1 0.1 2e-41 140.5 0.1 2.0 1 0 0 1 1 1 1 PIG-P MFS_1 PF07690.11 KFX93474.1 - 1.7e-36 125.7 56.1 1.7e-36 125.7 38.9 3.2 3 0 0 3 3 3 2 Major Facilitator Superfamily DUF605 PF04652.11 KFX93474.1 - 0.1 11.9 4.2 0.18 11.1 2.9 1.3 1 0 0 1 1 1 0 Vta1 like WSC PF01822.14 KFX93475.1 - 4.5e-39 132.2 26.5 5.8e-21 74.2 7.0 2.8 3 0 0 3 3 3 2 WSC domain ABC2_membrane PF01061.19 KFX93476.1 - 1.1e-92 308.9 59.9 5.7e-49 166.1 12.7 3.9 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 KFX93476.1 - 3.7e-40 135.7 0.2 2.1e-32 110.8 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 KFX93476.1 - 8.7e-40 136.1 0.0 7.1e-19 68.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 KFX93476.1 - 3.3e-19 68.7 0.0 5.5e-18 64.8 0.0 2.6 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KFX93476.1 - 4.6e-08 32.7 0.0 0.00034 20.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 KFX93476.1 - 1e-05 25.4 0.1 0.0081 16.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KFX93476.1 - 1.1e-05 24.6 0.1 0.0029 16.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFX93476.1 - 2.9e-05 24.1 1.8 0.0034 17.4 0.1 3.0 3 0 0 3 3 3 1 AAA ATPase domain ABC2_membrane_3 PF12698.2 KFX93476.1 - 5.6e-05 22.3 15.5 5.6e-05 22.3 10.8 3.4 2 2 1 3 3 3 1 ABC-2 family transporter protein cobW PF02492.14 KFX93476.1 - 0.00014 21.3 2.7 0.0076 15.7 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 KFX93476.1 - 0.0017 19.2 0.0 0.84 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KFX93476.1 - 0.0023 17.2 0.1 0.091 11.9 0.0 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFX93476.1 - 0.0028 17.1 2.2 0.054 13.0 0.3 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KFX93476.1 - 0.0084 16.4 0.2 1 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KFX93476.1 - 0.0089 16.0 0.1 1.1 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KFX93476.1 - 0.01 16.2 0.1 1.3 9.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein NACHT PF05729.7 KFX93476.1 - 0.04 13.5 1.8 5.2 6.6 0.1 2.6 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.18 KFX93476.1 - 0.042 13.8 0.0 4.9 7.1 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.1 KFX93476.1 - 0.061 13.4 1.0 4 7.5 0.1 2.9 3 0 0 3 3 2 0 AAA domain PDR_assoc PF08370.6 KFX93476.1 - 0.13 11.7 6.9 0.31 10.5 0.2 3.6 3 0 0 3 3 3 0 Plant PDR ABC transporter associated AAA_19 PF13245.1 KFX93476.1 - 0.78 9.5 5.5 5.7 6.7 0.1 3.2 3 0 0 3 3 2 0 Part of AAA domain AAA_10 PF12846.2 KFX93476.1 - 2.5 7.4 4.3 13 5.1 0.1 3.0 3 0 0 3 3 3 0 AAA-like domain Striatin PF08232.7 KFX93477.1 - 6.9e-35 120.2 0.4 6.9e-35 120.2 0.2 2.8 2 1 0 2 2 2 1 Striatin family WD40 PF00400.27 KFX93477.1 - 1.1e-33 113.9 16.6 7.8e-10 38.2 0.1 6.8 6 1 0 6 6 6 5 WD domain, G-beta repeat Pho88 PF10032.4 KFX93478.1 - 2e-82 275.0 0.2 2.9e-82 274.5 0.2 1.2 1 0 0 1 1 1 1 Phosphate transport (Pho88) Dpy19 PF10034.4 KFX93478.1 - 0.027 12.6 0.4 0.035 12.2 0.3 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation MFS_1 PF07690.11 KFX93481.1 - 1.8e-28 99.2 32.4 2.7e-28 98.6 22.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PARP PF00644.15 KFX93482.1 - 6e-63 212.0 0.1 2.4e-62 210.0 0.0 2.0 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 KFX93482.1 - 9.2e-40 135.3 0.1 1.5e-39 134.6 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 KFX93482.1 - 1.8e-19 69.4 0.7 1.8e-19 69.4 0.5 2.5 2 1 0 2 2 2 1 WGR domain BRCT PF00533.21 KFX93482.1 - 2.5e-11 43.5 0.0 5.1e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KFX93482.1 - 5.9e-06 26.0 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain Metallophos PF00149.23 KFX93483.1 - 5.6e-34 117.2 0.7 9.1e-34 116.6 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 KFX93483.1 - 2.8e-15 56.1 0.1 2.8e-15 56.1 0.1 2.4 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 KFX93483.1 - 6.1e-10 38.2 0.1 5.6e-08 31.7 0.0 2.3 2 0 0 2 2 2 2 PhoD-like phosphatase Metallophos_2 PF12850.2 KFX93483.1 - 0.072 12.9 0.0 0.21 11.4 0.0 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Mucin PF01456.12 KFX93484.1 - 0.13 12.0 10.9 0.26 11.0 7.5 1.4 1 1 0 1 1 1 0 Mucin-like glycoprotein p450 PF00067.17 KFX93485.1 - 3.6e-28 98.2 0.0 8.5e-28 97.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_S64 PF08192.6 KFX93486.1 - 0.0015 16.9 1.3 0.0056 15.0 0.0 2.1 2 1 0 2 2 2 1 Peptidase family S64 Peptidase_S32 PF05579.8 KFX93486.1 - 0.094 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Prothymosin PF03247.9 KFX93491.1 - 6.7 6.9 19.1 13 5.9 13.2 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family Ribosomal_L16 PF00252.13 KFX93493.1 - 1.7e-31 108.7 0.1 2.3e-31 108.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e IncA PF04156.9 KFX93494.1 - 0.0011 18.6 12.8 0.0011 18.6 8.8 2.8 3 0 0 3 3 3 1 IncA protein Med23 PF11573.3 KFX93494.1 - 0.23 8.7 0.1 0.31 8.3 0.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 23 Phage_GPO PF05929.6 KFX93494.1 - 0.78 8.9 8.3 1.6 7.8 5.7 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase FUSC PF04632.7 KFX93494.1 - 2.1 6.7 5.4 3.6 5.9 3.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3919 PF13057.1 KFX93494.1 - 2.2 7.7 7.3 0.28 10.6 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3919) V_ATPase_I PF01496.14 KFX93494.1 - 9.6 3.9 9.8 6.4 4.4 5.5 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Cyt-b5 PF00173.23 KFX93495.1 - 1.6e-19 69.4 0.1 1.7e-19 69.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain EFP_N PF08207.7 KFX93495.1 - 0.016 15.0 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Ceramidase PF05875.7 KFX93496.1 - 3.2e-72 242.8 5.1 3.8e-72 242.5 3.5 1.0 1 0 0 1 1 1 1 Ceramidase Glyco_transf_64 PF09258.5 KFX93496.1 - 0.13 11.4 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 64 domain Hydrophobin_2 PF06766.6 KFX93497.1 - 0.16 11.7 7.8 1.2 8.8 5.4 2.1 1 1 0 1 1 1 0 Fungal hydrophobin SIS PF01380.17 KFX93498.1 - 1.7e-13 50.3 0.1 3.6e-13 49.2 0.1 1.6 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 KFX93498.1 - 0.00018 21.2 0.2 0.0022 17.7 0.0 2.4 2 1 1 3 3 3 1 SIS domain DUF2810 PF10928.3 KFX93498.1 - 0.0087 15.7 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2810) DUF3670 PF12419.3 KFX93498.1 - 0.029 13.8 0.1 0.058 12.8 0.1 1.4 1 0 0 1 1 1 0 SNF2 Helicase protein Vint PF14623.1 KFX93499.1 - 3.4e-41 140.4 0.0 5.7e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.1 KFX93499.1 - 2.6e-23 81.9 0.0 5.3e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.23 KFX93499.1 - 1.6e-20 73.5 0.0 2.7e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KFX93499.1 - 1.6e-20 73.8 0.0 5.1e-20 72.2 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.1 KFX93499.1 - 2.8e-13 49.8 0.0 6.1e-11 42.2 0.0 2.7 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 KFX93499.1 - 0.017 14.2 0.0 0.047 12.8 0.0 1.7 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.4 KFX93499.1 - 0.13 12.0 0.0 1.1 8.9 0.0 2.1 1 1 0 1 1 1 0 vWA found in TerF C terminus GMC_oxred_N PF00732.14 KFX93500.1 - 7.6e-64 215.6 0.0 9.8e-64 215.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFX93500.1 - 3.7e-31 108.3 0.0 6.5e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KFX93500.1 - 3.8e-05 22.7 0.1 6.2e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KFX93500.1 - 0.00019 21.3 0.1 0.014 15.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFX93500.1 - 0.00022 20.2 0.7 0.084 11.7 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFX93500.1 - 0.00073 18.4 0.4 0.12 11.1 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 KFX93500.1 - 0.039 12.5 0.1 0.057 12.0 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_8 PF13450.1 KFX93500.1 - 0.048 13.6 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFX93500.1 - 0.12 11.4 0.2 0.29 10.1 0.1 1.6 1 0 0 1 1 1 0 Thi4 family Lipase_GDSL_2 PF13472.1 KFX93502.1 - 4.1e-14 53.1 4.1 5.3e-14 52.7 2.9 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFX93502.1 - 7e-08 32.5 2.5 9.8e-08 32.1 1.7 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AMP-binding PF00501.23 KFX93503.1 - 1.1e-40 139.3 0.2 1.5e-40 138.9 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX93503.1 - 2.2e-16 60.5 0.0 5.3e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Metallophos PF00149.23 KFX93514.1 - 8.9e-17 61.1 0.0 1.7e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFX93514.1 - 5.2e-05 23.1 0.1 0.00013 21.8 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MBOAT PF03062.14 KFX93515.1 - 1.4e-31 109.8 22.3 1.6e-31 109.6 13.5 2.1 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Adaptin_N PF01602.15 KFX93516.1 - 4.6e-143 477.3 0.3 5.5e-143 477.0 0.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 KFX93516.1 - 6.7e-14 52.1 0.0 1.4e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 KFX93516.1 - 3e-06 27.4 2.2 0.053 13.8 0.0 4.5 4 2 1 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 KFX93516.1 - 0.00023 21.5 1.0 11 6.7 0.0 5.4 5 0 0 5 5 5 2 HEAT-like repeat Cnd1 PF12717.2 KFX93516.1 - 0.0016 18.3 3.2 0.065 13.0 0.6 3.1 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KFX93516.1 - 0.0081 16.1 3.3 13 6.1 0.0 5.5 5 1 0 5 5 5 1 HEAT repeat TIP120 PF08623.5 KFX93516.1 - 0.014 15.0 0.3 0.058 12.9 0.0 2.2 2 0 0 2 2 2 0 TATA-binding protein interacting (TIP20) AAA_17 PF13207.1 KFX93517.1 - 2.9e-16 60.3 0.1 3.4e-16 60.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFX93517.1 - 3.3e-07 30.6 0.0 5.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KFX93517.1 - 2.8e-05 24.1 0.0 3.6e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFX93517.1 - 0.00049 19.9 0.0 0.00094 19.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KFX93517.1 - 0.0011 19.1 0.0 0.0016 18.6 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 KFX93517.1 - 0.0021 17.9 0.2 0.0079 16.0 0.0 1.9 1 1 1 2 2 2 1 Shikimate kinase DUF2075 PF09848.4 KFX93517.1 - 0.0038 16.2 0.0 0.006 15.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 KFX93517.1 - 0.0044 16.6 0.0 0.0054 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KFX93517.1 - 0.0047 15.8 0.0 0.0059 15.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain ABC_tran PF00005.22 KFX93517.1 - 0.0066 16.7 0.0 0.008 16.4 0.0 1.5 1 1 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.7 KFX93517.1 - 0.0069 15.4 0.0 0.0086 15.1 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 KFX93517.1 - 0.01 16.0 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KFX93517.1 - 0.019 14.9 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.4 KFX93517.1 - 0.022 14.2 0.0 0.03 13.7 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 KFX93517.1 - 0.026 14.2 0.2 0.048 13.3 0.2 1.7 1 1 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 KFX93517.1 - 0.041 13.6 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Miro PF08477.8 KFX93517.1 - 0.043 14.3 0.0 0.064 13.7 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_25 PF13481.1 KFX93517.1 - 0.06 12.7 0.2 0.12 11.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFX93517.1 - 0.09 12.9 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 RNA helicase NTPase_1 PF03266.10 KFX93517.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 NTPase cobW PF02492.14 KFX93517.1 - 0.13 11.6 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 KFX93517.1 - 0.13 12.2 0.1 0.19 11.7 0.1 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Cytidylate_kin2 PF13189.1 KFX93517.1 - 0.13 12.1 0.1 0.22 11.4 0.1 1.4 1 1 0 1 1 1 0 Cytidylate kinase-like family RuvB_N PF05496.7 KFX93517.1 - 0.17 10.9 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus TauD PF02668.11 KFX93522.1 - 8.7e-60 202.5 0.2 1.3e-59 202.0 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KFX93522.1 - 0.026 13.4 0.0 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 CsiD 2OG-FeII_Oxy_3 PF13640.1 KFX93522.1 - 0.03 14.8 0.2 0.067 13.7 0.1 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Mito_carr PF00153.22 KFX93523.1 - 2.8e-66 219.2 4.5 2.1e-22 78.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TFIID_30kDa PF03540.8 KFX93524.1 - 2.2e-26 91.4 0.2 3.1e-26 90.9 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.1 KFX93524.1 - 0.28 11.6 0.3 0.28 11.6 0.2 1.7 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 DUF962 PF06127.6 KFX93526.1 - 2.5e-24 85.0 0.0 4.2e-24 84.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF3270 PF11674.3 KFX93526.1 - 0.29 11.1 1.5 0.86 9.6 0.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3270) SHS2_Rpb7-N PF03876.12 KFX93527.1 - 4.2e-10 39.5 0.0 7e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KFX93527.1 - 1.6e-08 34.4 0.0 2.8e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 KFX93527.1 - 0.00075 19.6 0.1 0.0017 18.5 0.0 1.6 1 1 1 2 2 2 1 RNA polymerase III subunit Rpc25 XPG_I PF00867.13 KFX93528.1 - 5.3e-22 77.6 0.0 9.5e-22 76.8 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KFX93528.1 - 0.00079 19.6 0.0 0.0019 18.4 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain ADH_N PF08240.7 KFX93529.1 - 5.5e-06 26.1 0.0 7.7e-06 25.6 0.0 1.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CTD PF12815.2 KFX93530.1 - 9.3e-26 90.6 59.1 2.1e-22 79.8 24.4 5.2 2 1 2 4 4 4 3 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 KFX93530.1 - 5e-25 87.0 0.1 9.1e-25 86.2 0.1 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 KFX93530.1 - 4e-21 75.4 9.6 4e-21 75.4 6.7 3.6 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 KFX93530.1 - 8.4e-09 34.8 12.3 0.0011 18.5 0.0 5.5 6 0 0 6 6 6 2 KOW motif Nucleo_P87 PF07267.6 KFX93530.1 - 6.3 5.3 17.5 11 4.5 12.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Abhydrolase_5 PF12695.2 KFX93531.1 - 4.1e-06 26.6 0.0 4.5e-05 23.2 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX93531.1 - 0.0005 20.0 1.0 0.0029 17.4 0.7 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KFX93531.1 - 0.065 12.6 0.0 0.39 10.1 0.0 2.0 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Polysacc_deac_1 PF01522.16 KFX93538.1 - 7.6e-33 112.7 0.0 1.2e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 KFX93538.1 - 0.00027 20.8 14.4 0.00071 19.5 10.0 1.7 1 0 0 1 1 1 1 Chitin recognition protein Glyco_hydro_57 PF03065.10 KFX93538.1 - 0.00079 18.4 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 nec1 PF10379.4 KFX93538.1 - 1.4 8.1 5.3 19 4.4 0.0 2.4 2 0 0 2 2 2 0 Virulence protein nec1 CH PF00307.26 KFX93539.1 - 2.9e-38 130.2 0.1 7.4e-19 67.7 0.0 2.9 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 KFX93539.1 - 1.9e-25 88.5 0.1 6.3e-25 86.9 0.0 2.0 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 KFX93539.1 - 5.4e-13 48.4 0.0 5.2e-07 29.2 0.0 2.7 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.1 KFX93539.1 - 0.00035 20.2 0.1 0.0036 17.0 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain Spectrin PF00435.16 KFX93539.1 - 0.00047 20.4 3.4 0.17 12.1 0.0 2.8 2 0 0 2 2 2 2 Spectrin repeat EF-hand_1 PF00036.27 KFX93539.1 - 0.011 14.9 0.1 0.096 12.0 0.0 2.6 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 KFX93539.1 - 0.012 15.2 0.4 0.091 12.3 0.0 2.7 2 1 1 3 3 3 0 EF-hand domain pair Rabaptin PF03528.10 KFX93539.1 - 0.025 14.5 0.1 0.46 10.4 0.0 2.9 2 1 0 2 2 2 0 Rabaptin EIAV_Rev PF11129.3 KFX93539.1 - 0.15 12.0 1.5 0.34 10.8 1.0 1.5 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus RIX1 PF08167.7 KFX93541.1 - 5.3e-48 162.8 0.1 1.1e-47 161.7 0.1 1.6 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis TPR_12 PF13424.1 KFX93542.1 - 0.0046 16.8 5.1 6.1 6.8 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFX93542.1 - 0.012 15.5 5.2 37 4.5 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFX93542.1 - 0.052 13.7 0.0 6.6 7.1 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFX93542.1 - 0.073 13.4 2.3 52 4.2 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFX93542.1 - 0.13 12.9 11.9 17 6.3 0.1 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFX93542.1 - 0.19 12.4 0.1 0.19 12.4 0.1 4.9 7 0 0 7 7 7 0 Tetratricopeptide repeat Ank_2 PF12796.2 KFX93548.1 - 7.8e-85 279.3 26.3 8.3e-20 70.9 0.2 6.5 2 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 KFX93548.1 - 5.3e-60 196.3 38.0 5.8e-07 29.0 0.1 13.1 14 0 0 14 14 14 10 Ankyrin repeat Ank_4 PF13637.1 KFX93548.1 - 1.5e-51 171.9 25.6 5.5e-10 39.4 0.2 9.2 4 3 7 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX93548.1 - 2.2e-43 141.9 19.6 0.00075 19.5 0.0 13.0 13 0 0 13 13 13 10 Ankyrin repeat Ank_5 PF13857.1 KFX93548.1 - 4e-34 115.8 18.9 8.7e-05 22.6 0.2 10.2 2 2 8 10 10 10 9 Ankyrin repeats (many copies) NACHT PF05729.7 KFX93548.1 - 1.6e-05 24.6 0.0 4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Syntaxin PF00804.20 KFX93548.1 - 0.028 14.5 1.4 0.52 10.5 0.0 2.9 2 0 0 2 2 2 0 Syntaxin AAA PF00004.24 KFX93548.1 - 0.044 13.9 0.0 0.56 10.4 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Ank_2 PF12796.2 KFX93549.1 - 1.7e-19 69.9 0.1 2.2e-09 37.5 0.1 3.2 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFX93549.1 - 2.1e-15 55.6 3.5 4.2e-05 23.1 0.1 6.6 6 1 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 KFX93549.1 - 2.7e-14 51.8 0.8 0.0017 18.3 0.0 7.5 6 2 2 8 8 8 3 Ankyrin repeat Ank_5 PF13857.1 KFX93549.1 - 1.2e-12 47.6 5.8 1.1e-08 35.0 0.3 4.3 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Acetyltransf_1 PF00583.19 KFX93549.1 - 5.6e-09 35.9 0.0 1.3e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ank_4 PF13637.1 KFX93549.1 - 3.9e-08 33.5 5.0 0.0013 19.1 0.1 5.1 2 1 4 6 6 6 2 Ankyrin repeats (many copies) Acetyltransf_7 PF13508.1 KFX93549.1 - 6.1e-06 26.2 0.0 4.5e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX93549.1 - 0.00028 20.9 0.0 0.0026 17.8 0.0 2.6 3 1 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFX93549.1 - 0.056 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 KFX93549.1 - 0.099 11.9 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 GDC-P PF02347.11 KFX93550.1 - 2.7e-178 593.0 0.0 3.7e-167 556.3 0.0 2.8 2 1 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 KFX93550.1 - 1.1e-06 28.0 0.1 1.9e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KFX93550.1 - 0.043 12.8 0.2 0.12 11.3 0.0 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Baculo_PEP_C PF04513.7 KFX93552.1 - 0.15 11.8 3.6 2.8 7.7 2.6 2.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus VBS PF08913.5 KFX93552.1 - 0.19 11.9 3.6 1.1 9.5 2.5 2.2 1 1 0 1 1 1 0 Vinculin Binding Site CLPTM1 PF05602.7 KFX93553.1 - 1e-160 535.2 0.0 1.2e-160 535.0 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Lysine_decarbox PF03641.9 KFX93554.1 - 6.9e-31 106.8 0.0 9.8e-31 106.3 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase Vps55 PF04133.9 KFX93555.1 - 2.7e-46 156.2 5.1 3e-46 156.0 3.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 GtrA PF04138.9 KFX93555.1 - 0.079 12.9 2.7 0.13 12.2 1.9 1.3 1 1 0 1 1 1 0 GtrA-like protein Proteasome PF00227.21 KFX93556.1 - 3.2e-47 160.2 0.1 4e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFX93556.1 - 4.4e-11 41.8 0.2 7.1e-11 41.2 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Chorismate_bind PF00425.13 KFX93557.1 - 2.3e-64 217.1 0.0 4.9e-36 124.3 0.0 2.3 2 0 0 2 2 2 2 chorismate binding enzyme GATase PF00117.23 KFX93557.1 - 1.1e-21 77.2 0.0 5e-20 71.7 0.0 2.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 KFX93557.1 - 2.5e-15 56.7 0.0 4.8e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 KFX93557.1 - 0.0066 15.9 1.1 0.051 13.0 0.8 2.1 1 1 0 1 1 1 1 Peptidase C26 PagL PF09411.5 KFX93557.1 - 0.022 14.8 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipid A 3-O-deacylase (PagL) IP_trans PF02121.13 KFX93557.1 - 0.099 11.8 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 Phosphatidylinositol transfer protein UAA PF08449.6 KFX93558.1 - 1.5e-12 47.0 19.5 1.9e-12 46.7 13.5 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KFX93558.1 - 2.4e-08 33.7 8.3 2.4e-08 33.7 5.7 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KFX93558.1 - 1.4e-05 25.0 27.7 0.00044 20.2 6.9 2.3 2 0 0 2 2 2 2 EamA-like transporter family Thioredoxin PF00085.15 KFX93559.1 - 2.2e-07 30.5 0.0 4.1e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 KFX93559.1 - 1.2e-05 24.1 0.1 1.5e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Phosducin Mt_ATP-synt_B PF05405.9 KFX93559.1 - 0.061 12.7 0.2 0.098 12.1 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Thioredoxin_7 PF13899.1 KFX93559.1 - 0.13 12.2 0.4 0.94 9.5 0.1 2.1 2 0 0 2 2 2 0 Thioredoxin-like ARD PF03079.9 KFX93560.1 - 1.3e-43 148.7 0.1 1.3e-43 148.7 0.1 1.6 2 0 0 2 2 2 1 ARD/ARD' family adh_short PF00106.20 KFX93560.1 - 7.8e-19 68.2 0.0 1.2e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX93560.1 - 1e-08 35.0 0.0 2.1e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 KR domain Cupin_2 PF07883.6 KFX93560.1 - 2.8e-08 33.1 0.0 6.5e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Epimerase PF01370.16 KFX93560.1 - 2.8e-06 26.9 0.0 9.4e-06 25.2 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family AraC_binding PF02311.14 KFX93560.1 - 1.9e-05 24.3 0.0 4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain adh_short_C2 PF13561.1 KFX93560.1 - 0.0007 19.4 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Cupin_1 PF00190.17 KFX93560.1 - 0.004 16.6 0.0 0.0072 15.7 0.0 1.3 1 0 0 1 1 1 1 Cupin NAD_binding_10 PF13460.1 KFX93560.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding GIDA PF01134.17 KFX93561.1 - 3.4e-159 529.9 0.0 4.9e-159 529.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 KFX93561.1 - 9e-16 57.7 0.0 2.2e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 KFX93561.1 - 4.3e-08 33.2 0.1 9.3e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KFX93561.1 - 1.2e-06 27.8 0.1 2.2e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 KFX93561.1 - 2.4e-05 23.4 0.4 0.067 12.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFX93561.1 - 0.00036 19.4 1.2 0.0007 18.5 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 KFX93561.1 - 0.0069 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 KFX93561.1 - 0.092 11.1 4.6 0.073 11.5 0.3 2.4 3 0 0 3 3 3 0 HI0933-like protein Pet127 PF08634.5 KFX93562.1 - 7.1e-115 382.8 0.1 9.6e-115 382.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 POP1 PF06978.6 KFX93562.1 - 2.6e-15 56.5 8.6 2.6e-15 56.5 5.9 2.6 2 1 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 Mst1_SARAH PF11629.3 KFX93563.1 - 0.046 13.5 3.1 0.15 11.8 2.2 1.9 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 TT_ORF2 PF02957.10 KFX93563.1 - 0.18 12.5 1.5 0.45 11.2 1.0 1.6 1 0 0 1 1 1 0 TT viral ORF2 FUSC PF04632.7 KFX93563.1 - 0.49 8.7 2.0 0.62 8.4 1.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-MYND PF01753.13 KFX93564.1 - 1.8e-11 43.6 11.5 3.7e-11 42.6 8.0 1.5 1 0 0 1 1 1 1 MYND finger zf-C2HC5 PF06221.8 KFX93564.1 - 0.042 13.6 4.6 0.079 12.7 3.2 1.4 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Ecl1 PF12855.2 KFX93564.1 - 0.17 11.1 5.8 0.39 10.0 4.0 1.5 1 0 0 1 1 1 0 Life-span regulatory factor DUF3742 PF12553.3 KFX93565.1 - 0.17 12.3 2.3 0.3 11.5 0.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3742) UDG PF03167.14 KFX93567.1 - 4.1e-21 75.0 0.2 1e-20 73.7 0.0 1.7 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily UDPGP PF01704.13 KFX93568.1 - 3.5e-52 177.3 0.0 4.9e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 KFX93568.1 - 0.05 13.6 0.1 0.13 12.3 0.0 1.7 2 0 0 2 2 2 0 MobA-like NTP transferase domain APH PF01636.18 KFX93569.1 - 3.6e-13 49.8 0.0 3.1e-12 46.7 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 KFX93569.1 - 0.0059 15.7 0.0 0.0092 15.1 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase adh_short PF00106.20 KFX93570.1 - 1.7e-31 109.4 0.8 2.8e-31 108.6 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX93570.1 - 8.3e-31 107.5 0.4 9.8e-31 107.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX93570.1 - 1.3e-12 47.7 0.3 1.9e-12 47.2 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFX93570.1 - 0.00036 20.5 0.1 0.0019 18.2 0.0 1.7 1 1 1 2 2 2 1 NADH(P)-binding E1-N PF14463.1 KFX93570.1 - 0.15 11.6 4.0 0.81 9.2 0.0 2.7 3 0 0 3 3 3 0 E1 N-terminal domain Eno-Rase_NADH_b PF12242.3 KFX93570.1 - 0.84 9.4 3.3 0.75 9.6 0.1 2.4 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.20 KFX93571.1 - 2.6e-07 30.7 0.1 4e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KFX93571.1 - 0.00022 21.2 0.0 0.00032 20.7 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 KFX93571.1 - 0.001 18.8 0.1 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase F420_oxidored PF03807.12 KFX93571.1 - 0.0052 17.1 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 KFX93571.1 - 0.0061 15.8 0.1 0.029 13.6 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family 2-Hacid_dh_C PF02826.14 KFX93571.1 - 0.011 14.8 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KFX93571.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KFX93571.1 - 0.027 14.5 0.0 0.041 13.9 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF904 PF06005.7 KFX93572.1 - 0.064 13.5 0.2 0.13 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Sipho_Gp157 PF05565.6 KFX93572.1 - 0.085 12.4 0.8 0.11 12.0 0.6 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 FlaC_arch PF05377.6 KFX93572.1 - 0.1 12.5 0.2 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Antimicrobial_8 PF08103.6 KFX93572.1 - 0.18 11.7 1.4 4.3 7.4 0.1 2.8 2 1 1 3 3 3 0 Uperin family TBPIP PF07106.8 KFX93572.1 - 0.23 10.9 2.6 0.32 10.5 1.7 1.3 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Glyco_hydro_76 PF03663.9 KFX93576.1 - 1.2e-100 337.5 4.6 1.5e-100 337.2 3.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 AT_hook PF02178.14 KFX93578.1 - 0.0013 18.1 11.8 0.78 9.6 5.5 3.1 2 0 0 2 2 2 2 AT hook motif SET PF00856.23 KFX93580.1 - 4.8e-23 82.2 0.3 4.8e-23 82.2 0.2 3.0 2 2 0 2 2 2 1 SET domain SRI PF08236.6 KFX93580.1 - 3.3e-20 71.8 9.0 9.5e-20 70.3 6.2 1.8 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 KFX93580.1 - 0.15 11.5 0.5 0.64 9.5 0.1 2.1 2 0 0 2 2 2 0 TFIIS helical bundle-like domain WW PF00397.21 KFX93580.1 - 4.6 7.2 6.0 23 4.9 4.2 2.1 1 1 0 1 1 1 0 WW domain AA_permease_2 PF13520.1 KFX93581.1 - 2.7e-91 306.2 34.2 3.6e-91 305.8 23.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFX93581.1 - 1.1e-19 70.1 32.9 1.7e-19 69.5 22.8 1.1 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.20 KFX93597.1 - 1.4e-24 86.8 1.4 5.4e-24 84.9 0.9 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX93597.1 - 1.3e-08 34.7 0.9 0.0002 21.0 0.1 2.3 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 KFX93597.1 - 1.2e-06 28.4 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFX93597.1 - 4.7e-05 22.9 0.0 7.5e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KFX93597.1 - 0.0018 17.2 0.0 0.003 16.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KFX93597.1 - 0.0025 17.8 0.0 0.0053 16.7 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding PGAP1 PF07819.8 KFX93598.1 - 5.7e-88 294.2 0.0 7.8e-88 293.8 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KFX93598.1 - 1.2e-06 28.3 0.0 2.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX93598.1 - 0.00085 19.2 0.1 0.0027 17.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX93598.1 - 0.017 14.6 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.9 KFX93598.1 - 0.028 13.6 0.0 0.06 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) COesterase PF00135.23 KFX93598.1 - 0.057 12.1 0.0 0.08 11.6 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family p450 PF00067.17 KFX93600.1 - 3.1e-47 161.1 0.0 5.9e-47 160.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 E1-E2_ATPase PF00122.15 KFX93605.1 - 2.2e-58 197.0 7.3 8.4e-44 149.3 1.3 2.7 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFX93605.1 - 1e-30 106.5 2.9 1e-30 106.5 2.0 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFX93605.1 - 1e-29 104.5 0.0 2.2e-28 100.1 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFX93605.1 - 2.2e-18 65.4 0.0 6.2e-18 64.0 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFX93605.1 - 1.2e-13 51.6 0.1 3.6e-13 50.1 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFX93605.1 - 5.3e-13 48.7 0.0 1e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFX93605.1 - 2.2e-05 24.1 2.8 7.3e-05 22.4 0.8 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2510 PF10708.4 KFX93605.1 - 0.11 12.0 0.1 0.3 10.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2510) Flavin_Reduct PF01613.13 KFX93605.1 - 0.12 12.2 0.1 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Flavin reductase like domain KRE9 PF05390.6 KFX93607.1 - 2e-12 47.4 4.6 2.4e-12 47.1 3.2 1.1 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 Peptidase_M24 PF00557.19 KFX93608.1 - 2e-52 177.7 0.0 2.7e-52 177.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KFX93608.1 - 4.7e-25 87.5 0.0 4.2e-24 84.4 0.0 2.5 3 0 0 3 3 3 1 Aminopeptidase P, N-terminal domain PALP PF00291.20 KFX93609.1 - 9.2e-61 205.7 0.2 1.2e-60 205.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 KFX93609.1 - 3.7e-10 39.4 0.0 6e-08 32.3 0.0 2.7 2 0 0 2 2 2 2 CBS domain HA2 PF04408.18 KFX93613.1 - 7.6e-17 61.2 0.0 2.6e-16 59.4 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFX93613.1 - 1.8e-12 46.9 0.0 4.6e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFX93613.1 - 6.9e-11 41.9 0.0 1.4e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFX93613.1 - 9.6e-08 32.2 0.0 3.8e-07 30.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.11 KFX93613.1 - 1.1e-06 28.5 0.1 3.8e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_29 PF13555.1 KFX93613.1 - 0.0006 19.2 0.0 0.0022 17.4 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KFX93613.1 - 0.002 18.4 0.1 0.013 15.7 0.0 2.3 2 0 0 2 2 2 1 ABC transporter FtsK_SpoIIIE PF01580.13 KFX93613.1 - 0.01 15.3 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family KaiC PF06745.8 KFX93613.1 - 0.021 13.9 0.0 0.044 12.8 0.0 1.5 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.17 KFX93613.1 - 0.021 13.6 0.0 0.041 12.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 KFX93613.1 - 0.038 13.6 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_23 PF13476.1 KFX93613.1 - 1.2 9.4 0.0 1.2 9.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain DUF3554 PF12074.3 KFX93614.1 - 5.3e-79 266.0 1.1 5.3e-79 266.0 0.7 4.0 4 1 0 4 4 4 1 Domain of unknown function (DUF3554) Ribosomal_L19e PF01280.15 KFX93614.1 - 5.7e-59 198.1 6.8 5.7e-59 198.1 4.7 2.1 1 1 0 1 1 1 1 Ribosomal protein L19e HEAT PF02985.17 KFX93614.1 - 7.7e-32 106.5 23.9 0.024 14.6 0.0 20.5 22 0 0 22 22 22 6 HEAT repeat HEAT_2 PF13646.1 KFX93614.1 - 9.3e-31 105.9 46.4 6.9e-09 35.8 0.0 15.4 7 4 11 18 18 18 10 HEAT repeats HEAT_EZ PF13513.1 KFX93614.1 - 4e-29 100.3 45.4 1.5e-05 25.3 0.0 20.1 11 5 11 22 22 22 9 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFX93614.1 - 2.2e-14 53.5 0.0 1.8 9.0 0.0 10.3 8 3 2 10 10 10 3 Vacuolar 14 Fab1-binding region ParcG PF10274.4 KFX93614.1 - 1e-10 41.7 3.0 0.0028 17.5 0.0 7.1 9 1 0 9 9 9 2 Parkin co-regulated protein CLASP_N PF12348.3 KFX93614.1 - 1.4e-09 37.6 0.0 0.054 12.8 0.0 5.8 5 2 1 6 6 6 3 CLASP N terminal Cnd1 PF12717.2 KFX93614.1 - 2.7e-07 30.6 0.4 1.8 8.4 0.0 7.0 8 1 1 9 9 9 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 KFX93614.1 - 1.3 7.6 16.2 0.33 9.6 0.3 5.8 5 1 1 6 6 6 0 RNAPII transcription regulator C-terminal RmuC PF02646.11 KFX93615.1 - 0.027 13.3 0.1 0.034 12.9 0.1 1.1 1 0 0 1 1 1 0 RmuC family DUF1664 PF07889.7 KFX93615.1 - 0.04 13.7 0.1 0.067 12.9 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Parvo_NS1 PF01057.12 KFX93620.1 - 0.061 12.1 0.1 0.068 12.0 0.1 1.0 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TPR_1 PF00515.23 KFX93621.1 - 5e-52 171.4 21.3 5.5e-08 32.0 0.0 10.6 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 KFX93621.1 - 5.1e-46 150.9 16.5 1.6e-05 24.4 0.0 10.5 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 KFX93621.1 - 6.5e-45 150.6 18.6 1e-10 41.1 0.6 6.4 2 2 2 6 6 6 6 TPR repeat TPR_8 PF13181.1 KFX93621.1 - 3e-36 120.4 13.1 1e-05 24.9 0.6 10.3 8 1 2 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.1 KFX93621.1 - 1.4e-30 105.2 16.8 2.1e-06 28.2 0.0 7.5 4 2 3 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 KFX93621.1 - 4e-29 100.3 18.5 7.2e-07 29.0 0.1 7.1 3 2 5 8 8 8 8 Tetratricopeptide repeat TPR_17 PF13431.1 KFX93621.1 - 1.4e-28 96.6 13.9 0.0021 18.1 0.1 10.0 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_14 PF13428.1 KFX93621.1 - 3.2e-24 83.2 13.0 0.00015 22.0 0.0 10.2 4 2 7 11 11 10 7 Tetratricopeptide repeat TPR_7 PF13176.1 KFX93621.1 - 2.9e-20 70.4 9.4 0.002 17.7 0.0 10.0 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_6 PF13174.1 KFX93621.1 - 4.9e-20 70.5 13.3 0.0061 16.9 0.0 9.9 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFX93621.1 - 8.4e-18 64.4 21.2 0.0001 22.5 0.0 6.4 4 1 3 8 8 7 7 Tetratricopeptide repeat Apc3 PF12895.2 KFX93621.1 - 3.8e-15 55.7 7.3 3e-08 33.6 1.1 4.0 3 2 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KFX93621.1 - 1.3e-13 50.5 6.7 0.00088 19.0 0.2 6.2 1 1 5 7 7 7 5 Tetratricopeptide repeat TPR_15 PF13429.1 KFX93621.1 - 7e-09 35.1 7.3 0.00066 18.8 2.2 5.1 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_21 PF09976.4 KFX93621.1 - 5.4e-07 29.6 7.2 0.025 14.5 0.0 4.1 4 1 1 5 5 3 3 Tetratricopeptide repeat TPR_20 PF14561.1 KFX93621.1 - 1.5e-05 25.0 0.0 0.27 11.3 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat hNIFK_binding PF12196.3 KFX93621.1 - 0.0027 17.0 0.1 0.0089 15.3 0.1 1.9 1 0 0 1 1 1 1 FHA Ki67 binding domain of hNIFK ChAPs PF09295.5 KFX93621.1 - 0.012 14.3 1.5 2.4 6.8 0.1 2.8 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) MIT PF04212.13 KFX93621.1 - 0.026 14.4 7.7 0.72 9.7 0.1 4.8 5 1 0 5 5 4 0 MIT (microtubule interacting and transport) domain DUF2225 PF09986.4 KFX93621.1 - 0.026 14.0 3.1 0.33 10.3 0.0 2.8 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_10 PF13374.1 KFX93621.1 - 1.3 9.0 13.6 24 5.0 0.1 6.6 8 0 0 8 8 8 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.19 KFX93623.1 - 3e-06 27.1 0.0 5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 KFX93623.1 - 2.3e-05 24.1 0.0 4.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.1 KFX93623.1 - 7.3e-05 22.8 0.0 0.00034 20.7 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 KFX93623.1 - 0.013 16.0 0.0 0.091 13.3 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX93623.1 - 0.082 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HSP70 PF00012.15 KFX93624.1 - 2e-59 201.0 2.0 2.2e-57 194.3 0.0 2.7 3 0 0 3 3 3 2 Hsp70 protein Peptidase_M22 PF00814.20 KFX93624.1 - 0.014 14.8 0.2 0.066 12.7 0.0 2.2 3 0 0 3 3 3 0 Glycoprotease family Mucin PF01456.12 KFX93624.1 - 5.7 6.7 27.6 2.7 7.7 0.9 3.4 3 0 0 3 3 3 0 Mucin-like glycoprotein Prefoldin_2 PF01920.15 KFX93625.1 - 2.6e-25 88.2 4.3 3.3e-25 87.9 3.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit FTA4 PF13093.1 KFX93625.1 - 0.0073 15.7 2.3 0.009 15.4 1.6 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Prefoldin PF02996.12 KFX93625.1 - 0.11 12.1 3.4 0.48 10.0 0.1 2.2 1 1 1 2 2 2 0 Prefoldin subunit Spc24 PF08286.6 KFX93625.1 - 0.47 10.1 7.7 2 8.1 2.3 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.6 KFX93625.1 - 0.67 9.8 5.6 0.57 10.1 0.3 2.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) AAA_23 PF13476.1 KFX93625.1 - 2.2 8.5 9.2 4 7.7 6.4 1.4 1 1 0 1 1 1 0 AAA domain Macoilin PF09726.4 KFX93625.1 - 3.3 5.8 5.8 5.8 5.0 2.5 1.9 2 0 0 2 2 2 0 Transmembrane protein DUF2951 PF11166.3 KFX93625.1 - 3.6 7.4 8.5 41 4.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) SspP PF08179.7 KFX93626.1 - 0.032 14.4 0.3 0.055 13.6 0.2 1.4 1 0 0 1 1 1 0 Small acid-soluble spore protein P family DUF1183 PF06682.7 KFX93626.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Vpu PF00558.14 KFX93626.1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Vpu protein APC10 PF03256.11 KFX93627.1 - 1.1e-49 168.6 0.0 1.6e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Daxx PF03344.10 KFX93627.1 - 1.1 7.6 8.9 1.4 7.2 6.2 1.1 1 0 0 1 1 1 0 Daxx Family CobT PF06213.7 KFX93627.1 - 9.5 5.2 16.3 13 4.7 11.3 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SDA1 PF05285.7 KFX93628.1 - 3.8e-96 322.1 30.8 3.8e-96 322.1 21.4 2.4 3 0 0 3 3 3 2 SDA1 NUC130_3NT PF08158.7 KFX93628.1 - 5.9e-20 71.2 0.0 1.6e-19 69.9 0.0 1.8 1 0 0 1 1 1 1 NUC130/3NT domain ACCA PF03255.9 KFX93628.1 - 0.036 13.6 3.0 0.038 13.5 0.2 2.3 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Spt20 PF12090.3 KFX93629.1 - 1.8e-43 148.0 0.0 1.8e-43 148.0 0.0 5.3 3 2 1 4 4 4 1 Spt20 family Hexapep PF00132.19 KFX93631.1 - 1e-07 31.1 2.7 0.0071 15.8 0.3 2.8 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KFX93631.1 - 0.0013 18.8 0.0 0.0035 17.4 0.0 1.8 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.7 KFX93631.1 - 0.005 15.4 1.3 1.6 7.1 0.1 2.2 1 1 1 2 2 2 2 L-fucokinase NTP_transferase PF00483.18 KFX93631.1 - 0.0098 15.2 0.0 0.019 14.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase zf-C2H2_4 PF13894.1 KFX93632.1 - 5.7e-07 29.4 8.4 0.0088 16.3 0.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFX93632.1 - 3.8e-05 23.7 2.6 3.8e-05 23.7 1.8 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KFX93632.1 - 0.00095 19.3 15.2 0.0075 16.5 3.1 3.4 2 1 0 2 2 2 2 Zinc finger, C2H2 type BTB PF00651.26 KFX93633.1 - 0.00016 21.6 0.1 0.00049 20.0 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain NUDIX PF00293.23 KFX93637.1 - 9.7e-16 57.6 0.6 1.1e-15 57.4 0.4 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.1 KFX93637.1 - 0.0022 17.3 0.0 0.0029 16.9 0.0 1.3 1 0 0 1 1 1 1 Nucleotide hydrolase CFEM PF05730.6 KFX93640.1 - 4.3e-42 141.7 59.7 1.1e-10 41.1 6.5 4.5 4 0 0 4 4 4 4 CFEM domain Esterase_phd PF10503.4 KFX93641.1 - 1e-25 90.2 0.1 1.4e-25 89.8 0.1 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KFX93641.1 - 3.8e-08 32.7 1.0 7e-08 31.9 0.7 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFX93641.1 - 1.1e-05 25.2 0.1 1.8e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KFX93641.1 - 0.013 14.2 0.5 0.021 13.5 0.3 1.3 1 0 0 1 1 1 0 Carboxylesterase family DUF3429 PF11911.3 KFX93643.1 - 0.0024 17.8 4.3 0.0024 17.8 3.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3429) SAE2 PF08573.5 KFX93644.1 - 1.5e-28 99.3 0.2 5.2e-28 97.5 0.2 2.0 1 0 0 1 1 1 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Glyco_hydro_7 PF00840.15 KFX93646.1 - 1.6e-161 537.4 18.8 1.9e-161 537.2 13.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 p450 PF00067.17 KFX93647.1 - 1.3e-19 70.1 0.0 1.8e-14 53.1 0.0 2.9 1 1 2 3 3 3 3 Cytochrome P450 FAD_binding_4 PF01565.18 KFX93648.1 - 2.5e-19 69.1 2.4 3.2e-19 68.7 1.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 KFX93649.1 - 5e-24 85.5 0.0 1.1e-23 84.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFX93649.1 - 9.6e-17 60.3 0.3 6.9e-16 57.5 0.2 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KFX93649.1 - 7.4e-12 44.8 0.7 1.6e-08 33.8 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KFX93649.1 - 8.7e-07 29.0 0.0 0.00037 20.4 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX93649.1 - 1.1e-06 28.5 0.0 3.4e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KFX93649.1 - 8e-05 22.7 0.1 0.07 13.2 0.0 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 KFX93649.1 - 0.00044 19.2 0.0 0.0072 15.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFX93649.1 - 0.011 14.5 0.0 0.018 13.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KFX93649.1 - 0.051 12.6 1.1 0.086 11.9 0.0 1.8 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.1 KFX93649.1 - 0.094 12.4 0.0 0.55 9.9 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KFX93649.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KFX93649.1 - 0.11 10.9 0.4 0.22 9.9 0.3 1.5 1 0 0 1 1 1 0 HI0933-like protein GPI2 PF06432.6 KFX93650.1 - 2.4e-120 401.1 0.3 2.8e-120 400.9 0.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF3136 PF11334.3 KFX93650.1 - 0.024 14.0 0.3 0.052 12.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) Annexin PF00191.15 KFX93651.1 - 3.1e-19 68.6 3.6 0.00021 21.1 0.0 4.4 4 0 0 4 4 4 4 Annexin bZIP_1 PF00170.16 KFX93652.1 - 0.00024 20.9 6.3 0.00024 20.9 4.3 1.7 2 0 0 2 2 2 1 bZIP transcription factor LURAP PF14854.1 KFX93652.1 - 6.7 6.4 7.7 0.12 12.1 0.2 1.9 3 0 0 3 3 3 0 Leucine rich adaptor protein Lactonase PF10282.4 KFX93653.1 - 5.8e-07 28.9 0.1 4.7e-05 22.6 0.0 2.8 1 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller PQQ PF01011.16 KFX93653.1 - 1.3 8.6 4.2 4.1 7.1 0.1 3.6 5 0 0 5 5 5 0 PQQ enzyme repeat Hemerythrin PF01814.18 KFX93654.1 - 3.2e-11 43.5 0.1 4.9e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Pirin PF02678.11 KFX93655.1 - 1.4e-22 79.5 1.0 4.1e-22 78.0 0.7 1.8 1 1 0 1 1 1 1 Pirin ADH_N PF08240.7 KFX93655.1 - 6.3e-11 42.0 0.1 5.5e-10 38.9 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFX93655.1 - 3e-07 31.3 0.0 7.5e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Cupin_2 PF07883.6 KFX93655.1 - 1.4e-05 24.5 3.7 4.3e-05 22.9 0.5 3.0 2 1 0 2 2 2 1 Cupin domain RNA_pol_Rpb1_1 PF04997.7 KFX93656.1 - 1.3e-109 366.5 0.0 2.4e-109 365.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 KFX93656.1 - 1.7e-105 352.2 0.1 2.5e-105 351.6 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KFX93656.1 - 2.5e-71 238.9 0.0 5.3e-71 237.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 KFX93656.1 - 1.2e-58 197.9 6.0 2.9e-58 196.6 4.2 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 KFX93656.1 - 1.8e-48 164.2 0.0 4.8e-48 162.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 KFX93656.1 - 8e-44 148.6 5.8 2.4e-43 147.0 4.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 KFX93656.1 - 1.6e-37 127.5 0.1 3.7e-37 126.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 KFX93656.1 - 4.7e-06 26.2 176.4 0.11 12.6 4.4 13.2 14 0 0 14 14 14 11 RNA polymerase Rpb1 C-terminal repeat Prp19_bind PF06991.6 KFX93657.1 - 0.17 11.0 7.7 0.27 10.4 5.3 1.2 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain DUF3359 PF11839.3 KFX93657.1 - 7.6 6.9 11.0 5.5 7.4 5.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3359) Zip PF02535.17 KFX93659.1 - 5.2 5.9 5.5 6.8 5.6 3.8 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter Pyr_redox PF00070.22 KFX93661.1 - 9.5e-15 54.7 0.0 7.1e-11 42.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFX93661.1 - 1.6e-13 51.0 0.0 3.1e-12 46.8 0.0 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFX93661.1 - 4.2e-08 32.4 0.0 0.00012 21.1 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KFX93661.1 - 6.3e-08 32.9 0.1 0.00016 21.7 0.0 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFX93661.1 - 0.0035 16.3 0.0 1.9 7.2 0.0 2.4 3 0 0 3 3 3 2 Lycopene cyclase protein ApbA PF02558.11 KFX93661.1 - 0.0037 16.7 0.0 0.0072 15.7 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.19 KFX93661.1 - 0.0047 15.8 0.1 0.08 11.8 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase TrkA_N PF02254.13 KFX93661.1 - 0.0067 16.4 0.1 0.89 9.5 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_9 PF13454.1 KFX93661.1 - 0.015 15.1 0.0 7.4 6.3 0.0 3.8 4 0 0 4 4 4 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KFX93661.1 - 0.14 10.7 0.8 18 3.8 0.0 2.9 2 1 1 3 3 3 0 Tryptophan halogenase Isochorismatase PF00857.15 KFX93662.1 - 2e-18 66.9 0.0 3.3e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family TrbH PF07283.6 KFX93662.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Conjugal transfer protein TrbH Glyco_hydro_43 PF04616.9 KFX93663.1 - 1.1e-33 116.5 2.9 1.7e-33 115.9 2.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 FAD_binding_3 PF01494.14 KFX93663.1 - 2.8e-22 79.2 0.0 4.2e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KFX93663.1 - 6.4e-07 28.7 0.3 0.00086 18.4 0.0 2.5 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KFX93663.1 - 0.00012 21.1 0.0 0.00022 20.2 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein CBM_1 PF00734.13 KFX93663.1 - 0.00012 21.6 8.7 0.00032 20.2 6.0 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain NAD_binding_8 PF13450.1 KFX93663.1 - 0.00062 19.7 0.0 0.0021 18.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFX93663.1 - 0.0036 16.2 0.7 0.73 8.6 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HTH_Tnp_Tc3_2 PF01498.13 KFX93663.1 - 0.067 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 Transposase Pyr_redox PF00070.22 KFX93663.1 - 0.082 13.3 3.0 0.26 11.7 0.1 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF2204 PF09970.4 KFX93663.1 - 0.36 10.2 0.0 0.65 9.4 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) p450 PF00067.17 KFX93664.1 - 2.6e-56 191.0 0.0 1.3e-34 119.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.17 KFX93665.1 - 2.1e-57 194.6 0.0 3.4e-57 194.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Phage_GPO PF05929.6 KFX93665.1 - 0.14 11.4 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF3437 PF11919.3 KFX93666.1 - 3.8e-31 106.6 0.0 1e-30 105.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 KFX93666.1 - 0.0079 16.1 0.6 6 7.2 0.0 4.7 3 0 0 3 3 3 1 HEAT repeat Protoglobin PF11563.3 KFX93666.1 - 0.078 12.6 0.0 1.8 8.2 0.0 2.9 3 0 0 3 3 3 0 Protoglobin HEAT_EZ PF13513.1 KFX93666.1 - 0.58 10.7 8.8 20 5.8 0.1 5.5 3 1 2 5 5 5 0 HEAT-like repeat VCBS PF13517.1 KFX93686.1 - 2.7e-28 98.0 37.4 3.8e-14 52.7 1.5 8.6 3 2 7 10 10 10 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KFX93686.1 - 2.1e-15 55.8 28.2 0.0011 18.6 0.8 7.4 6 0 0 6 6 6 6 FG-GAP repeat Lipase_GDSL PF00657.17 KFX93686.1 - 1.4e-13 51.2 0.7 1.4e-13 51.2 0.5 3.0 3 0 0 3 3 3 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KFX93686.1 - 1.8e-13 50.9 0.6 6.3e-13 49.2 0.4 2.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 KFX93686.1 - 0.00048 19.9 0.0 0.0011 18.7 0.0 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.3 KFX93686.1 - 0.00099 18.5 10.1 0.73 9.2 0.1 5.6 6 1 1 7 7 7 2 Insecticide toxin TcdB middle/N-terminal region Pectate_lyase_3 PF12708.2 KFX93687.1 - 5.1e-88 294.9 12.9 2e-68 230.8 4.7 2.6 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KFX93687.1 - 5.8e-07 28.8 3.7 0.0038 16.6 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase NosD PF05048.8 KFX93687.1 - 0.08 12.0 6.1 0.026 13.6 1.7 2.0 2 0 0 2 2 2 0 Periplasmic copper-binding protein (NosD) Myb_DNA-bind_4 PF13837.1 KFX93688.1 - 0.0068 16.5 0.8 0.022 14.8 0.1 2.2 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Stk19 PF10494.4 KFX93691.1 - 2.6e-29 102.3 0.0 3.3e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Fe-ADH PF00465.14 KFX93692.1 - 5.9e-74 248.8 0.3 6.7e-74 248.7 0.2 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KFX93692.1 - 1.7e-13 50.4 0.1 2.5e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DUF1677 PF07911.8 KFX93692.1 - 0.18 11.9 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) Meth_synt_2 PF01717.13 KFX93693.1 - 9.6e-14 51.0 0.0 8.6e-10 38.0 0.0 2.6 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KFX93693.1 - 6.2e-05 22.4 0.0 0.066 12.4 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain NurA PF09376.5 KFX93693.1 - 0.0068 15.9 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 NurA domain Aldolase_II PF00596.16 KFX93694.1 - 2.6e-39 134.7 1.9 3.4e-39 134.3 1.3 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Dabb PF07876.7 KFX93695.1 - 6.7e-12 45.7 0.0 7.4e-12 45.5 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF1338 PF07063.8 KFX93696.1 - 9.5e-77 258.0 0.0 1.1e-76 257.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Fungal_trans PF04082.13 KFX93697.1 - 8.5e-16 57.6 0.3 8.5e-16 57.6 0.2 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX93697.1 - 7.4e-08 32.1 9.9 1.3e-07 31.3 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KFX93698.1 - 2.1e-19 69.4 13.9 2.1e-19 69.4 9.6 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX93698.1 - 0.0057 15.2 9.0 0.0057 15.2 6.2 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter PsbH PF00737.15 KFX93698.1 - 0.23 11.0 2.9 15 5.2 0.1 2.9 2 1 0 2 2 2 0 Photosystem II 10 kDa phosphoprotein Dioxygenase_C PF00775.16 KFX93699.1 - 1.2e-46 158.3 0.0 1.5e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KFX93699.1 - 4.3e-13 49.0 0.0 8.8e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KFX93699.1 - 0.0016 18.4 0.0 0.0039 17.2 0.0 1.6 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain ADH_zinc_N PF00107.21 KFX93700.1 - 4.1e-26 91.0 0.1 7.3e-26 90.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX93700.1 - 1.2e-11 44.2 1.2 1.2e-10 41.0 0.0 2.8 2 2 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFX93700.1 - 8.2e-06 26.7 0.0 2.6e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase LSM PF01423.17 KFX93702.1 - 1.3e-17 63.1 0.2 1.6e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF4403 PF14356.1 KFX93703.1 - 0.0029 15.9 0.3 0.0033 15.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4403) BNR PF02012.15 KFX93705.1 - 0.019 14.6 0.1 0.042 13.6 0.1 1.6 1 0 0 1 1 1 0 BNR/Asp-box repeat BNR_2 PF13088.1 KFX93705.1 - 0.02 14.2 0.0 0.02 14.2 0.0 1.0 1 0 0 1 1 1 0 BNR repeat-like domain p450 PF00067.17 KFX93706.1 - 3.2e-67 227.0 0.0 4.3e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 KFX93707.1 - 2.4e-08 33.7 5.5 5e-08 32.7 3.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KFX93708.1 - 2.7e-46 158.0 0.0 5.1e-46 157.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 KFX93709.1 - 7.7e-18 64.9 0.0 1.6e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX93709.1 - 0.0023 17.7 0.0 0.0032 17.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX93709.1 - 0.012 15.3 0.3 0.045 13.4 0.0 2.1 2 1 0 2 2 2 0 KR domain Epimerase PF01370.16 KFX93709.1 - 0.037 13.4 0.0 0.18 11.2 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KFX93709.1 - 0.11 12.3 0.2 0.35 10.6 0.1 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MFS_1 PF07690.11 KFX93710.1 - 1.6e-40 138.9 52.9 1.6e-40 138.9 36.7 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFX93710.1 - 1.7e-13 49.6 28.3 2.4e-13 49.1 19.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SHP PF03579.8 KFX93710.1 - 0.02 14.2 1.2 0.081 12.2 0.8 2.1 1 0 0 1 1 1 0 Small hydrophobic protein Transferase PF02458.10 KFX93711.1 - 9.6e-21 73.7 0.0 8.7e-19 67.2 0.0 2.6 1 1 0 1 1 1 1 Transferase family Luteo_Vpg PF01659.11 KFX93711.1 - 0.1 12.2 6.6 0.3 10.7 4.6 1.8 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein Proteasome PF00227.21 KFX93713.1 - 1.6e-16 60.1 0.0 2.1e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit PDE6_gamma PF04868.7 KFX93713.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit eIF3_subunit PF08597.5 KFX93714.1 - 2.5e-67 227.0 19.9 2.8e-67 226.8 13.8 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Erythro_esteras PF05139.9 KFX93716.1 - 7e-135 449.6 2.4 8.1e-135 449.4 1.7 1.0 1 0 0 1 1 1 1 Erythromycin esterase ABC_membrane PF00664.18 KFX93717.1 - 2.4e-75 253.5 17.9 9.5e-45 153.1 4.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFX93717.1 - 1.1e-63 213.5 0.1 3.6e-34 118.0 0.0 3.0 2 1 0 2 2 2 2 ABC transporter Exo_endo_phos PF03372.18 KFX93717.1 - 1.3e-22 80.9 0.1 2.6e-22 79.9 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SMC_N PF02463.14 KFX93717.1 - 1e-14 54.2 3.1 0.00019 20.7 0.1 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain LRR_4 PF12799.2 KFX93717.1 - 9.4e-12 44.2 2.2 3.3e-09 36.1 0.3 2.5 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) AAA_21 PF13304.1 KFX93717.1 - 1.4e-11 44.9 0.2 0.064 13.2 0.0 4.9 3 2 1 4 4 4 3 AAA domain DUF258 PF03193.11 KFX93717.1 - 7.2e-09 35.0 0.0 0.00098 18.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 KFX93717.1 - 7.8e-09 34.6 1.2 0.001 17.7 0.0 4.7 5 0 0 5 5 5 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 KFX93717.1 - 9e-09 35.5 0.2 0.0001 22.3 0.0 2.8 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.1 KFX93717.1 - 1.7e-08 33.8 1.2 0.0024 17.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KFX93717.1 - 9.5e-08 32.8 0.0 0.01 16.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KFX93717.1 - 1.6e-07 31.5 1.1 0.037 14.1 0.0 4.1 4 1 0 4 4 3 2 AAA domain LRR_8 PF13855.1 KFX93717.1 - 1.3e-06 28.0 0.1 2.9e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 Leucine rich repeat AAA_23 PF13476.1 KFX93717.1 - 3.8e-06 27.3 0.1 0.02 15.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KFX93717.1 - 7.4e-06 25.6 1.0 0.061 12.8 0.1 3.6 3 1 0 3 3 2 2 AAA domain LRR_1 PF00560.28 KFX93717.1 - 1.9e-05 24.0 0.2 0.074 13.1 0.1 3.1 2 0 0 2 2 2 1 Leucine Rich Repeat AAA_18 PF13238.1 KFX93717.1 - 4e-05 23.9 0.1 0.23 11.7 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KFX93717.1 - 9.1e-05 22.1 0.2 0.21 11.3 0.0 3.3 3 0 0 3 3 2 1 Part of AAA domain AAA_25 PF13481.1 KFX93717.1 - 0.00022 20.6 2.4 0.47 9.8 0.0 3.2 4 0 0 4 4 3 2 AAA domain AAA_33 PF13671.1 KFX93717.1 - 0.00035 20.4 0.1 1.3 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KFX93717.1 - 0.00041 19.4 0.1 0.056 12.5 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin AAA PF00004.24 KFX93717.1 - 0.00075 19.7 2.7 0.21 11.7 0.1 4.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFX93717.1 - 0.00075 19.2 0.1 0.84 9.3 0.0 3.3 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 KFX93717.1 - 0.0021 17.5 2.0 0.54 9.6 0.1 2.8 3 0 0 3 3 3 1 AAA-like domain Rad17 PF03215.10 KFX93717.1 - 0.0024 16.6 0.0 0.14 10.8 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 KFX93717.1 - 0.0026 17.7 0.0 1.3 9.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KFX93717.1 - 0.0026 17.6 0.0 0.63 9.9 0.0 3.2 3 0 0 3 3 2 1 AAA domain MobB PF03205.9 KFX93717.1 - 0.0033 17.1 0.5 2.8 7.6 0.0 3.1 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 KFX93717.1 - 0.0038 17.1 0.7 1.9 8.4 0.1 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 KFX93717.1 - 0.0077 15.7 1.1 1.1 8.7 0.0 2.9 4 0 0 4 4 2 1 ATP synthase alpha/beta family, nucleotide-binding domain PRK PF00485.13 KFX93717.1 - 0.0081 15.7 0.0 2.4 7.7 0.0 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_15 PF13175.1 KFX93717.1 - 0.015 14.3 0.0 1.6 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_11 PF13086.1 KFX93717.1 - 0.018 14.6 0.0 4 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KFX93717.1 - 0.03 14.2 0.0 4.7 7.2 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.1 KFX93717.1 - 0.031 13.8 0.2 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain LRR_7 PF13504.1 KFX93717.1 - 0.032 14.3 0.2 3.7 8.1 0.1 3.1 2 0 0 2 2 2 0 Leucine rich repeat ATP_bind_1 PF03029.12 KFX93717.1 - 0.032 13.7 0.1 4.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.17 KFX93717.1 - 0.035 12.9 0.5 0.82 8.4 0.0 2.5 3 0 0 3 3 2 0 NB-ARC domain RNA_helicase PF00910.17 KFX93717.1 - 0.038 14.1 0.1 5.2 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.12 KFX93717.1 - 0.038 13.8 0.6 2.2 8.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 APS_kinase PF01583.15 KFX93717.1 - 0.09 12.4 0.1 2.2 7.9 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase Methyltransf_11 PF08241.7 KFX93719.1 - 7.6e-12 45.5 0.0 1.6e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX93719.1 - 7.7e-12 45.4 0.0 1.8e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX93719.1 - 1.3e-09 37.7 0.0 2.2e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX93719.1 - 8.1e-09 36.0 0.0 1.7e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX93719.1 - 6.1e-08 32.7 0.0 2.6e-07 30.6 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX93719.1 - 3e-07 30.3 0.0 5.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX93719.1 - 5.8e-06 26.6 0.0 1.2e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KFX93719.1 - 0.00012 22.0 0.0 0.0002 21.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 KFX93719.1 - 0.00025 20.7 0.0 0.00057 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX93719.1 - 0.0013 18.1 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 KFX93719.1 - 0.002 18.9 0.0 0.0058 17.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KFX93719.1 - 0.0054 16.1 0.0 0.0091 15.3 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 KFX93719.1 - 0.0059 16.1 0.0 0.023 14.2 0.0 1.8 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RE_MjaI PF09568.5 KFX93719.1 - 0.071 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 MjaI restriction endonuclease Methyltransf_8 PF05148.10 KFX93719.1 - 0.22 11.1 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Complex1_LYR_2 PF13233.1 KFX93720.1 - 2.6e-08 34.2 0.0 3.2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KFX93720.1 - 0.00083 19.1 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFX93720.1 - 0.0015 18.7 0.0 0.0018 18.4 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like 4HBT_2 PF13279.1 KFX93721.1 - 8.1e-21 74.7 0.0 1.4e-20 73.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 KFX93721.1 - 0.027 14.5 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily Acyl-ACP_TE PF01643.12 KFX93721.1 - 0.059 12.3 0.1 1.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Acyl-ACP thioesterase Pkinase PF00069.20 KFX93743.1 - 4.8e-05 22.6 0.0 7.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain His_Phos_1 PF00300.17 KFX93743.1 - 0.034 14.2 0.0 0.44 10.6 0.0 2.6 2 1 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) RIO1 PF01163.17 KFX93743.1 - 0.056 12.7 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family NCA2 PF08637.5 KFX93743.1 - 0.21 10.4 0.0 0.36 9.6 0.0 1.3 1 0 0 1 1 1 0 ATP synthase regulation protein NCA2 Pkinase PF00069.20 KFX93744.1 - 3.4e-10 39.4 0.0 4.4e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX93744.1 - 0.00043 19.4 0.0 0.00056 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFX93744.1 - 0.0007 18.7 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFX93744.1 - 0.0083 15.8 0.2 0.0083 15.8 0.1 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFX93744.1 - 0.029 13.7 0.2 0.064 12.5 0.0 1.6 2 0 0 2 2 2 0 RIO1 family YrbL-PhoP_reg PF10707.4 KFX93744.1 - 0.048 12.9 0.0 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL NmrA PF05368.8 KFX93746.1 - 7.4e-23 81.0 0.0 8.9e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX93746.1 - 8.7e-12 45.4 0.1 1.2e-11 44.9 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KFX93746.1 - 1e-05 24.7 0.0 1.5e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 KFX93746.1 - 0.045 13.6 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Gly_transf_sug PF04488.10 KFX93747.1 - 4e-13 49.6 0.0 8.4e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif PAT1 PF09770.4 KFX93748.1 - 0.98 7.5 28.8 1.1 7.3 20.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 IMS PF00817.15 KFX93749.1 - 1.8e-42 144.6 0.0 2.8e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KFX93749.1 - 7e-13 48.6 0.0 1.5e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KFX93749.1 - 0.0039 17.1 0.0 0.0096 15.9 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif F-box-like PF12937.2 KFX93750.1 - 0.00024 20.7 0.0 0.00058 19.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like Fungal_lectin PF07938.7 KFX93751.1 - 5.2e-76 255.8 10.5 5.9e-76 255.7 7.3 1.0 1 0 0 1 1 1 1 Fungal fucose-specific lectin PP-binding PF00550.20 KFX93756.1 - 1.3e-11 44.6 0.1 1.6e-11 44.2 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 KFX93756.1 - 2e-07 30.9 0.1 2.7e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 KFX93756.1 - 0.021 14.9 0.1 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) GPP34 PF05719.6 KFX93757.1 - 3.1e-64 216.8 0.1 4e-64 216.4 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) SURF6 PF04935.7 KFX93758.1 - 5.3e-46 156.5 16.2 7e-46 156.2 11.2 1.0 1 0 0 1 1 1 1 Surfeit locus protein 6 HSP70 PF00012.15 KFX93803.1 - 0.0042 15.0 0.0 0.0074 14.2 0.0 1.3 1 0 0 1 1 1 1 Hsp70 protein Pectinesterase PF01095.14 KFX93804.1 - 1.5e-46 158.3 7.2 1.9e-46 158.0 5.0 1.1 1 0 0 1 1 1 1 Pectinesterase Glyco_hydro_28 PF00295.12 KFX93805.1 - 2.6e-45 154.8 11.0 3.2e-45 154.5 7.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 End_N_terminal PF12218.3 KFX93805.1 - 0.009 15.4 0.0 0.026 13.9 0.0 1.8 1 0 0 1 1 1 1 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 KFX93805.1 - 0.031 14.0 18.1 0.5 10.1 12.5 2.7 1 1 0 1 1 1 0 Right handed beta helix region Transp_cyt_pur PF02133.10 KFX93807.1 - 2e-19 69.4 33.0 3.7e-19 68.6 22.9 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Oxidored_q1_C PF01010.14 KFX93807.1 - 0.027 13.9 0.1 4.2 6.8 0.0 2.4 2 0 0 2 2 2 0 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus p450 PF00067.17 KFX93808.1 - 5.7e-61 206.4 0.0 6.8e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NACHT PF05729.7 KFX93809.1 - 5.5e-12 45.6 0.0 5.5e-09 35.8 0.0 2.6 2 1 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 KFX93809.1 - 2.4e-11 43.9 0.5 1.4e-05 25.2 0.0 4.7 3 2 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 KFX93809.1 - 1.4e-10 41.3 0.0 0.00041 20.4 0.0 3.5 4 0 0 4 4 4 2 AAA domain NB-ARC PF00931.17 KFX93809.1 - 1.2e-06 27.5 0.0 0.00021 20.2 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.1 KFX93809.1 - 8.4e-06 25.3 0.0 0.0013 18.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KFX93809.1 - 3.6e-05 23.9 0.0 0.087 13.0 0.0 3.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KFX93809.1 - 0.00011 22.0 0.5 1.5 8.7 0.0 3.6 3 1 0 3 3 3 2 AAA domain Arch_ATPase PF01637.13 KFX93809.1 - 0.00017 21.3 0.0 0.0095 15.6 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_5 PF07728.9 KFX93809.1 - 0.00033 20.3 0.0 0.036 13.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KFX93809.1 - 0.0025 17.2 0.2 1.6 8.0 0.0 2.9 3 0 0 3 3 3 2 IstB-like ATP binding protein KAP_NTPase PF07693.9 KFX93809.1 - 0.0072 15.3 0.9 0.029 13.3 0.6 1.9 1 1 0 1 1 1 1 KAP family P-loop domain RNA_helicase PF00910.17 KFX93809.1 - 0.0085 16.2 0.0 1.7 8.8 0.0 2.8 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.22 KFX93809.1 - 0.012 15.9 0.2 5 7.4 0.0 3.4 3 0 0 3 3 3 0 ABC transporter AAA_17 PF13207.1 KFX93809.1 - 0.018 15.8 0.1 12 6.7 0.0 3.4 4 0 0 4 4 2 0 AAA domain AAA_33 PF13671.1 KFX93809.1 - 0.02 14.7 0.0 9.9 6.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF3764 PF12594.3 KFX93809.1 - 0.071 12.8 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3764) GMC_oxred_N PF00732.14 KFX93810.1 - 1.3e-47 162.4 0.0 2.3e-47 161.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFX93810.1 - 6.4e-38 130.2 0.1 1.4e-37 129.1 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Ank_2 PF12796.2 KFX93810.1 - 3.6e-25 88.1 0.7 3.9e-09 36.7 0.3 5.2 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFX93810.1 - 1.2e-23 82.5 3.7 5.3e-09 36.0 0.0 6.2 6 1 1 7 7 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFX93810.1 - 3.2e-21 75.2 5.8 1.1e-06 29.0 0.1 7.0 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 KFX93810.1 - 3.2e-13 48.7 6.4 1.9e-05 24.2 0.0 6.4 9 0 0 9 9 7 2 Ankyrin repeat Ank_3 PF13606.1 KFX93810.1 - 2.7e-11 42.5 2.3 0.057 13.6 0.0 8.1 11 0 0 11 11 6 2 Ankyrin repeat AAA_16 PF13191.1 KFX93810.1 - 1.7e-06 28.1 0.0 4.1e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 KFX93810.1 - 6.9e-05 22.0 0.1 0.0004 19.5 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin PGAP1 PF07819.8 KFX93810.1 - 0.00029 20.4 0.0 0.00072 19.2 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein DAO PF01266.19 KFX93810.1 - 0.00035 19.5 2.1 0.0014 17.6 1.3 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Abhydrolase_6 PF12697.2 KFX93810.1 - 0.00053 19.9 0.0 0.0029 17.5 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Pyr_redox_2 PF07992.9 KFX93810.1 - 0.00064 19.6 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFX93810.1 - 0.00082 18.3 0.6 0.032 13.0 0.9 2.3 2 0 0 2 2 2 1 FAD binding domain AAA_22 PF13401.1 KFX93810.1 - 0.00086 19.4 0.0 0.0028 17.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain NAD_binding_8 PF13450.1 KFX93810.1 - 0.0012 18.8 1.4 0.009 16.0 0.4 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FANCI_S2 PF14676.1 KFX93810.1 - 0.0018 18.1 0.2 0.0044 16.9 0.1 1.6 1 0 0 1 1 1 1 FANCI solenoid 2 Lycopene_cycl PF05834.7 KFX93810.1 - 0.0071 15.3 1.4 0.0082 15.1 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 KFX93810.1 - 0.012 14.7 1.1 0.023 13.7 0.2 1.8 2 0 0 2 2 2 0 Thi4 family NACHT PF05729.7 KFX93810.1 - 0.015 14.9 0.0 0.039 13.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.13 KFX93810.1 - 0.018 14.5 0.1 0.18 11.2 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.1 KFX93810.1 - 0.03 13.7 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pyr_redox_3 PF13738.1 KFX93810.1 - 0.039 14.0 0.5 3.3 7.7 0.2 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase LCAT PF02450.10 KFX93810.1 - 0.059 12.3 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase NAD_binding_9 PF13454.1 KFX93810.1 - 0.075 12.8 0.3 0.27 10.9 0.2 2.1 1 1 0 1 1 1 0 FAD-NAD(P)-binding Torsin PF06309.6 KFX93810.1 - 0.079 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Torsin AAA_10 PF12846.2 KFX93810.1 - 0.088 12.2 0.1 0.22 10.9 0.1 1.7 1 1 0 1 1 1 0 AAA-like domain Glyco_hydro_3 PF00933.16 KFX93811.1 - 1.5e-68 230.9 0.0 2e-68 230.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFX93811.1 - 1.7e-56 191.2 0.1 2.6e-56 190.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFX93811.1 - 3.7e-22 78.0 5.4 4.1e-22 77.8 0.6 2.4 2 0 0 2 2 2 1 Fibronectin type III-like domain Sugar-bind PF04198.8 KFX93811.1 - 0.016 14.1 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain DUF11 PF01345.13 KFX93811.1 - 0.89 9.6 7.8 1.6 8.8 2.2 2.6 1 1 1 2 2 2 0 Domain of unknown function DUF11 Sugar_tr PF00083.19 KFX93812.1 - 1.6e-88 297.2 29.2 1.8e-88 297.1 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX93812.1 - 2.3e-26 92.3 42.9 1.1e-25 90.1 16.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFX93812.1 - 1.1e-06 27.2 2.7 2e-06 26.3 1.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Acyl-CoA_ox_N PF14749.1 KFX93816.1 - 2.6e-27 95.5 0.7 4e-27 94.9 0.5 1.3 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 KFX93816.1 - 2.6e-05 23.6 0.0 5.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KFX93816.1 - 0.049 14.2 0.0 0.11 13.0 0.0 1.7 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, N-terminal domain MFS_1 PF07690.11 KFX93817.1 - 8.9e-29 100.2 37.4 8.9e-29 100.2 26.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 KFX93817.1 - 8e-05 20.8 4.6 0.0026 15.8 3.2 2.4 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Cytochrome-c551 PF10643.4 KFX93817.1 - 0.76 9.0 3.7 1.6 8.0 2.5 1.5 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 AMP-binding PF00501.23 KFX93818.1 - 3e-58 197.1 0.1 3.7e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX93818.1 - 5.6e-10 40.0 0.0 3e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NMO PF03060.10 KFX93818.1 - 0.043 12.9 0.2 0.064 12.3 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase tRNA_bind PF01588.15 KFX93844.1 - 2.8e-21 75.1 0.1 1.5e-20 72.8 0.1 2.0 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 KFX93844.1 - 1.2e-05 25.7 0.0 3.5e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFX93844.1 - 0.0059 16.4 0.1 0.017 15.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Fungal_trans PF04082.13 KFX93845.1 - 7.3e-28 97.1 0.0 2.8e-27 95.2 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX93845.1 - 1.7e-09 37.4 8.9 3e-09 36.6 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4306 PF14154.1 KFX93845.1 - 0.074 13.0 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) eIF-5_eIF-2B PF01873.12 KFX93852.1 - 2.8e-45 152.9 0.3 4.3e-45 152.4 0.2 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 DUF4604 PF15377.1 KFX93852.1 - 1.7 8.8 19.3 3.9 7.6 13.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) zf-HYPF PF07503.7 KFX93852.1 - 2.5 7.5 6.4 9.4 5.7 3.1 2.7 2 1 1 3 3 3 0 HypF finger Arc_trans_TRASH PF08394.5 KFX93852.1 - 2.8 8.1 6.3 2.9 8.1 0.2 2.8 1 1 1 2 2 2 0 Archaeal TRASH domain IFRD PF05004.8 KFX93853.1 - 0.11 11.5 0.4 0.13 11.3 0.3 1.1 1 0 0 1 1 1 0 Interferon-related developmental regulator (IFRD) FR47 PF08445.5 KFX93861.1 - 2.9e-05 23.7 0.1 6.6e-05 22.5 0.0 1.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 KFX93861.1 - 0.00022 21.3 0.0 0.00038 20.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX93861.1 - 0.0054 16.7 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFX93861.1 - 0.034 14.2 0.0 0.066 13.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KFX93861.1 - 0.047 13.8 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-C3HC4 PF00097.20 KFX93862.1 - 7.9e-09 35.0 3.9 7.9e-09 35.0 2.7 5.4 6 1 0 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFX93862.1 - 1.3e-05 25.1 4.5 1.3e-05 25.1 3.1 5.1 4 3 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX93862.1 - 1.3e-05 24.7 3.6 1.3e-05 24.7 2.5 5.8 4 3 0 4 4 4 1 zinc-RING finger domain zf-RING_6 PF14835.1 KFX93862.1 - 2.9e-05 23.7 0.7 2.9e-05 23.7 0.5 3.3 3 1 0 3 3 3 1 zf-RING of BARD1-type protein SH3_9 PF14604.1 KFX93862.1 - 0.00023 20.6 0.1 0.00023 20.6 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain GAGA PF09237.6 KFX93862.1 - 0.00065 19.2 1.6 0.007 15.9 0.4 2.6 2 0 0 2 2 2 1 GAGA factor zf-RING_UBOX PF13445.1 KFX93862.1 - 0.0038 16.9 1.5 0.0038 16.9 1.0 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFX93862.1 - 0.0046 16.7 5.5 0.0046 16.7 3.8 5.3 6 1 0 6 6 6 1 zinc finger of C3HC4-type, RING SH3_1 PF00018.23 KFX93862.1 - 0.044 13.1 0.1 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 SH3 domain Paired_CXXCH_1 PF09699.5 KFX93862.1 - 3.1 7.3 16.1 3 7.4 2.5 3.0 2 0 0 2 2 2 0 Doubled CXXCH motif (Paired_CXXCH_1) EBP PF05241.7 KFX93863.1 - 3e-63 212.3 11.5 3.5e-63 212.1 7.9 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF788 PF05620.6 KFX93863.1 - 3 7.6 7.1 0.22 11.3 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF788) RWD PF05773.17 KFX93864.1 - 9.1e-19 67.4 0.2 1.8e-18 66.4 0.2 1.5 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 KFX93864.1 - 6.3e-18 64.4 29.8 4.2e-11 42.5 1.0 3.9 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 KFX93864.1 - 2.9e-05 23.7 6.4 2.9e-05 23.7 4.4 3.8 2 1 1 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.1 KFX93864.1 - 0.00048 19.7 4.5 0.00048 19.7 3.1 3.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.1 KFX93864.1 - 0.00056 19.5 6.5 0.00056 19.5 4.5 4.0 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFX93864.1 - 0.0036 17.2 7.9 0.0036 17.2 5.5 4.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX93864.1 - 0.013 15.1 5.4 0.013 15.1 3.8 4.4 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFX93864.1 - 0.02 14.7 0.7 0.02 14.7 0.5 4.5 5 1 0 5 5 5 0 zinc finger of C3HC4-type, RING DUF1244 PF06844.6 KFX93864.1 - 0.13 12.0 2.8 1.4 8.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) FYVE PF01363.16 KFX93864.1 - 2.7 7.9 27.6 3.2 7.7 5.3 3.5 2 1 0 2 2 2 0 FYVE zinc finger NDT80_PhoG PF05224.7 KFX93865.1 - 1.5e-30 106.6 0.0 4.6e-30 104.9 0.0 1.9 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family DUF2011 PF09428.5 KFX93866.1 - 5.4e-20 71.6 19.1 2.2e-19 69.6 13.2 1.8 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF2011) CAF-1_p150 PF11600.3 KFX93866.1 - 0.038 13.3 15.2 0.064 12.6 10.5 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ank_2 PF12796.2 KFX93877.1 - 4.4e-87 286.5 0.1 8.9e-20 70.8 0.0 6.9 2 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KFX93877.1 - 2.5e-83 270.0 9.4 1.1e-06 28.1 0.1 13.9 14 0 0 14 14 14 13 Ankyrin repeat Ank_4 PF13637.1 KFX93877.1 - 9e-59 194.9 0.2 4.5e-09 36.5 0.0 9.9 4 4 6 10 10 10 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX93877.1 - 8.3e-58 186.5 0.8 5e-05 23.1 0.0 13.9 14 0 0 14 14 13 11 Ankyrin repeat Ank_5 PF13857.1 KFX93877.1 - 4.1e-50 166.6 12.1 3.4e-06 27.1 0.0 12.8 2 2 12 14 14 14 13 Ankyrin repeats (many copies) Abhydrolase_6 PF12697.2 KFX93877.1 - 0.0013 18.6 0.0 0.0029 17.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KFX93877.1 - 0.0019 17.5 0.0 0.003 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KFX93877.1 - 0.0022 17.6 0.0 0.0048 16.5 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KFX93877.1 - 0.0055 16.4 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 KFX93877.1 - 0.0065 16.0 0.0 0.24 10.9 0.0 3.0 3 0 0 3 3 3 1 Serine hydrolase DUF2305 PF10230.4 KFX93877.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF4182 PF13790.1 KFX93877.1 - 0.67 9.8 6.7 0.56 10.0 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4182) FHA PF00498.21 KFX93878.1 - 9e-17 60.9 0.1 3.2e-16 59.2 0.0 2.0 2 0 0 2 2 2 1 FHA domain TUDOR PF00567.19 KFX93878.1 - 0.15 11.8 0.2 5 6.9 0.0 2.9 3 0 0 3 3 3 0 Tudor domain DUF607 PF04678.8 KFX93878.1 - 3.4 7.5 6.7 2.5 7.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function, DUF607 Atg14 PF10186.4 KFX93878.1 - 7.1 5.4 13.6 7 5.4 3.4 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3405 PF11885.3 KFX93881.1 - 5.3e-161 536.2 0.2 6.4e-161 535.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Nefa_Nip30_N PF10187.4 KFX93882.1 - 5.3e-29 100.4 5.2 5.3e-29 100.4 3.6 2.5 2 1 1 3 3 3 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Ribosomal_L30_N PF08079.7 KFX93882.1 - 0.028 14.4 1.7 0.028 14.4 1.1 2.9 2 1 2 4 4 4 0 Ribosomal L30 N-terminal domain DUF2075 PF09848.4 KFX93882.1 - 0.058 12.3 2.2 0.075 12.0 1.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF572 PF04502.8 KFX93882.1 - 0.16 11.1 16.9 0.2 10.8 11.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) UVR PF02151.14 KFX93882.1 - 1.6 8.3 8.5 0.13 11.8 2.0 2.1 2 0 0 2 2 2 0 UvrB/uvrC motif DUF4614 PF15391.1 KFX93882.1 - 3 7.5 10.0 0.091 12.5 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4614) Aldo_ket_red PF00248.16 KFX93883.1 - 4.2e-51 173.4 0.0 5.4e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PI-PLC-X PF00388.14 KFX93884.1 - 1e-14 54.1 0.0 1.6e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Ribosomal_L10 PF00466.15 KFX93885.1 - 0.00099 18.9 0.0 0.013 15.3 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L10 Sterol_MT_C PF08498.5 KFX93885.1 - 0.093 12.6 0.5 0.62 10.0 0.0 2.2 2 0 0 2 2 2 0 Sterol methyltransferase C-terminal Glycos_transf_3 PF00591.16 KFX93886.1 - 1.8e-63 214.2 0.0 2.8e-63 213.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 KFX93886.1 - 3.2e-16 58.6 0.2 7.5e-16 57.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain CcdA PF07362.7 KFX93886.1 - 0.12 12.2 1.3 0.24 11.2 0.9 1.5 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA DNA_RNApol_7kD PF03604.8 KFX93887.1 - 7.5e-18 63.6 4.9 9.7e-18 63.3 3.4 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 KFX93887.1 - 0.0033 17.2 0.3 0.0045 16.7 0.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon DUF2197 PF09963.4 KFX93887.1 - 0.0048 16.8 1.9 0.61 10.0 0.0 2.1 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2197) A2L_zn_ribbon PF08792.5 KFX93887.1 - 0.006 16.0 0.9 0.35 10.3 0.0 2.2 2 0 0 2 2 2 1 A2L zinc ribbon domain GFA PF04828.9 KFX93887.1 - 0.013 15.4 0.2 3.7 7.5 0.0 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme HypA PF01155.14 KFX93887.1 - 0.014 15.0 0.2 0.016 14.8 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family TFIIS_C PF01096.13 KFX93887.1 - 0.015 14.8 0.7 3.4 7.3 0.2 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn-ribbon_8 PF09723.5 KFX93887.1 - 0.022 14.6 0.7 0.04 13.8 0.5 1.4 1 0 0 1 1 1 0 Zinc ribbon domain Zn_ribbon_recom PF13408.1 KFX93887.1 - 0.088 13.0 1.3 1.7 8.9 0.1 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF951 PF06107.6 KFX93887.1 - 0.13 11.7 0.3 2.1 7.9 0.2 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) RRN7 PF11781.3 KFX93887.1 - 0.28 10.6 2.5 0.53 9.8 0.1 2.1 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 ATP_bind_1 PF03029.12 KFX93888.1 - 4.1e-70 236.0 0.0 7e-70 235.2 0.0 1.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 KFX93888.1 - 8.8e-07 27.9 0.1 0.0011 17.7 0.0 2.2 2 0 0 2 2 2 2 ArgK protein GTP_EFTU PF00009.22 KFX93888.1 - 4.9e-06 26.1 0.0 0.00017 21.0 0.0 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KFX93888.1 - 0.00013 22.1 0.0 0.00041 20.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KFX93888.1 - 0.00024 21.5 0.0 0.4 11.1 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein AAA_10 PF12846.2 KFX93888.1 - 0.00027 20.4 0.1 0.00041 19.8 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain SRP54 PF00448.17 KFX93888.1 - 0.00034 20.1 0.0 0.016 14.6 0.0 3.0 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 KFX93888.1 - 0.00066 19.5 0.1 0.0019 18.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KFX93888.1 - 0.00069 19.5 0.0 0.0018 18.1 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 KFX93888.1 - 0.00094 20.0 0.1 0.0077 17.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KFX93888.1 - 0.0015 18.1 0.0 0.0047 16.6 0.0 1.7 2 0 0 2 2 2 1 NACHT domain Arf PF00025.16 KFX93888.1 - 0.0017 17.6 0.0 0.56 9.4 0.0 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family FeoB_N PF02421.13 KFX93888.1 - 0.0026 17.0 0.0 0.071 12.3 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B PRK PF00485.13 KFX93888.1 - 0.0028 17.2 0.0 0.0072 15.8 0.0 1.7 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 KFX93888.1 - 0.0032 17.4 0.0 0.0079 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.15 KFX93888.1 - 0.0067 15.1 0.6 0.43 9.1 0.0 2.6 2 1 0 2 2 2 1 G-protein alpha subunit CbiA PF01656.18 KFX93888.1 - 0.0067 15.8 0.7 0.018 14.4 0.0 2.0 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain PduV-EutP PF10662.4 KFX93888.1 - 0.0088 15.5 0.1 0.19 11.1 0.0 2.7 3 1 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 KFX93888.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KFX93888.1 - 0.011 14.8 0.0 0.027 13.5 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin cobW PF02492.14 KFX93888.1 - 0.013 14.9 0.0 0.63 9.4 0.0 2.4 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 KFX93888.1 - 0.013 14.3 0.5 0.023 13.5 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain MobB PF03205.9 KFX93888.1 - 0.014 15.1 0.1 0.036 13.7 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.5 KFX93888.1 - 0.11 11.6 0.0 0.26 10.4 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_19 PF13245.1 KFX93888.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 KFX93888.1 - 0.57 10.4 0.0 0.57 10.4 0.0 2.8 3 1 0 3 3 2 0 AAA domain CwfJ_C_1 PF04677.10 KFX93889.1 - 6.6e-28 96.8 0.0 1.1e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KFX93889.1 - 3.7e-26 91.4 0.0 3.7e-26 91.4 0.0 2.5 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 SET_assoc PF11767.3 KFX93889.1 - 0.085 12.1 0.3 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Zn_clus PF00172.13 KFX93890.1 - 1.2e-08 34.6 10.6 1.8e-08 34.1 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CRPV_capsid PF08762.5 KFX93890.1 - 0.029 13.8 1.3 0.046 13.1 0.9 1.3 1 0 0 1 1 1 0 CRPV capsid protein like DUF4175 PF13779.1 KFX93890.1 - 0.26 8.9 23.5 0.35 8.5 16.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF2347 PF09804.4 KFX93890.1 - 0.31 10.2 3.2 0.53 9.5 2.2 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Serinc PF03348.10 KFX93890.1 - 1.2 7.7 4.1 1.7 7.2 2.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Band_3_cyto PF07565.8 KFX93890.1 - 1.6 8.1 6.7 2.7 7.4 4.6 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Neur_chan_memb PF02932.11 KFX93890.1 - 1.7 8.4 4.1 2.6 7.8 2.8 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region KAR9 PF08580.5 KFX93890.1 - 2.1 6.5 17.0 2.8 6.1 11.8 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 FimP PF09766.4 KFX93890.1 - 2.8 6.9 14.8 4.6 6.2 10.2 1.2 1 0 0 1 1 1 0 Fms-interacting protein Hid1 PF12722.2 KFX93890.1 - 8.2 3.9 8.4 9.2 3.7 5.8 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CENP-S PF15630.1 KFX93892.1 - 2.5e-34 117.2 0.0 6.8e-34 115.9 0.0 1.7 2 0 0 2 2 2 1 Kinetochore component CENP-S CENP-T PF15511.1 KFX93892.1 - 0.00084 18.6 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 KFX93892.1 - 0.00091 18.9 0.0 0.0025 17.4 0.0 1.6 2 0 0 2 2 2 1 Bromodomain associated Histone PF00125.19 KFX93892.1 - 0.077 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Glyco_hydro_35 PF01301.14 KFX93893.1 - 7.5e-88 294.9 0.3 9.1e-88 294.6 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 KFX93893.1 - 7.7e-11 42.2 0.0 1.2e-05 25.5 0.0 3.1 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain ADH_zinc_N PF00107.21 KFX93894.1 - 1.1e-18 67.0 0.1 2.6e-18 65.8 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX93894.1 - 1.5e-14 54.9 0.0 3.6e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX93894.1 - 2.7e-11 43.1 0.0 7.2e-11 41.8 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 KFX93894.1 - 0.021 14.8 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding HATPase_c_3 PF13589.1 KFX93897.1 - 0.00014 21.5 0.0 0.00037 20.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3883 PF13020.1 KFX93897.1 - 0.0083 15.8 0.1 0.049 13.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3883) Peptidase_M18 PF02127.10 KFX93899.1 - 1.1e-135 452.5 0.0 1.9e-135 451.7 0.0 1.3 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) SNF2_N PF00176.18 KFX93900.1 - 5.4e-71 238.8 1.2 1.1e-70 237.7 0.8 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 KFX93900.1 - 7.7e-53 178.2 22.0 7.7e-53 178.2 15.3 3.8 3 1 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.26 KFX93900.1 - 5.6e-16 58.1 0.0 2.1e-15 56.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ABC_tran PF00005.22 KFX93901.1 - 2.3e-48 163.9 0.0 8.9e-28 97.2 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 KFX93901.1 - 1.7e-30 106.4 28.7 4.8e-19 68.8 7.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KFX93901.1 - 2.6e-14 53.8 3.7 0.0021 18.1 0.0 5.0 4 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 KFX93901.1 - 4.7e-10 39.0 5.4 0.067 12.4 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFX93901.1 - 6.8e-09 35.9 1.1 0.0021 18.0 0.1 2.8 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.1 KFX93901.1 - 1.2e-08 34.3 0.5 0.00078 18.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 KFX93901.1 - 3.7e-07 29.7 0.3 0.0003 20.2 0.1 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KFX93901.1 - 4e-06 26.7 0.1 0.12 12.3 0.1 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase DUF258 PF03193.11 KFX93901.1 - 1.8e-05 23.9 0.9 0.07 12.3 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 KFX93901.1 - 1.9e-05 25.1 1.3 0.16 12.5 0.1 2.6 2 0 0 2 2 2 2 Miro-like protein FtsK_SpoIIIE PF01580.13 KFX93901.1 - 0.00012 21.6 1.1 0.11 11.9 0.0 2.7 3 0 0 3 3 2 2 FtsK/SpoIIIE family AAA_10 PF12846.2 KFX93901.1 - 0.0002 20.9 3.3 0.063 12.7 0.3 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_22 PF13401.1 KFX93901.1 - 0.00022 21.3 4.1 0.064 13.4 0.1 3.3 3 1 0 3 3 2 1 AAA domain NTPase_1 PF03266.10 KFX93901.1 - 0.00023 20.9 2.4 0.091 12.4 0.6 2.4 2 0 0 2 2 2 2 NTPase AAA_23 PF13476.1 KFX93901.1 - 0.00029 21.2 0.4 0.12 12.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KFX93901.1 - 0.00034 19.6 0.4 0.018 13.9 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein MobB PF03205.9 KFX93901.1 - 0.00066 19.3 1.1 0.27 10.9 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 KFX93901.1 - 0.0011 18.8 1.6 0.034 13.9 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 cobW PF02492.14 KFX93901.1 - 0.0016 17.9 1.4 0.11 11.9 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 KFX93901.1 - 0.003 17.8 2.2 0.29 11.4 0.1 2.7 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 KFX93901.1 - 0.0033 16.2 0.9 0.88 8.2 0.1 2.2 2 0 0 2 2 2 1 ArgK protein ATP-synt_ab PF00006.20 KFX93901.1 - 0.0044 16.5 0.1 1.6 8.1 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 KFX93901.1 - 0.0084 16.3 0.0 0.48 10.6 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 KFX93901.1 - 0.0097 15.7 4.0 0.039 13.7 0.1 2.4 2 0 0 2 2 2 1 Dynamin family AAA_33 PF13671.1 KFX93901.1 - 0.014 15.2 1.7 0.57 10.0 0.2 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KFX93901.1 - 0.016 14.3 1.0 2.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Arch_ATPase PF01637.13 KFX93901.1 - 0.018 14.7 0.0 2.5 7.7 0.0 2.8 2 0 0 2 2 2 0 Archaeal ATPase ATP_bind_1 PF03029.12 KFX93901.1 - 0.018 14.5 0.7 1.6 8.2 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF815 PF05673.8 KFX93901.1 - 0.018 13.9 0.1 1.2 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 KFX93901.1 - 0.023 15.5 8.1 0.4 11.5 0.4 3.1 2 1 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 KFX93901.1 - 0.023 14.8 0.3 10 6.3 0.0 3.1 3 0 0 3 3 2 0 RNA helicase Septin PF00735.13 KFX93901.1 - 0.026 13.5 0.9 2.8 6.8 0.1 2.3 2 0 0 2 2 2 0 Septin AAA_14 PF13173.1 KFX93901.1 - 0.026 14.4 0.1 1 9.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 KFX93901.1 - 0.028 13.0 1.0 3.3 6.2 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NB-ARC PF00931.17 KFX93901.1 - 0.038 12.8 1.3 4 6.2 0.0 2.5 2 1 0 2 2 2 0 NB-ARC domain KAP_NTPase PF07693.9 KFX93901.1 - 0.078 11.9 0.0 4.9 6.0 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain NACHT PF05729.7 KFX93901.1 - 0.091 12.4 2.3 4.9 6.7 0.2 2.6 2 1 0 2 2 2 0 NACHT domain AAA_5 PF07728.9 KFX93901.1 - 0.12 12.1 0.3 4.6 6.9 0.1 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KFX93901.1 - 0.12 11.7 0.0 18 4.7 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.1 KFX93901.1 - 0.14 11.7 0.3 5.9 6.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KFX93901.1 - 0.15 11.8 0.8 0.5 10.1 0.2 2.1 2 0 0 2 2 1 0 Part of AAA domain AAA_15 PF13175.1 KFX93901.1 - 0.27 10.2 0.3 14 4.6 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain Viral_helicase1 PF01443.13 KFX93901.1 - 0.33 10.4 1.2 1.4 8.3 0.1 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA12 PF10443.4 KFX93901.1 - 0.4 9.1 0.2 0.75 8.2 0.0 1.4 2 0 0 2 2 1 0 RNA12 protein PRK PF00485.13 KFX93901.1 - 0.63 9.5 3.4 0.51 9.8 0.1 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_24 PF13479.1 KFX93901.1 - 0.72 9.3 1.5 50 3.3 0.1 3.2 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 KFX93902.1 - 3.5e-16 59.6 0.0 2e-15 57.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFX93902.1 - 9.5e-05 22.5 0.4 0.0066 16.5 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 KFX93902.1 - 0.0049 16.8 0.0 0.019 14.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 KFX93902.1 - 0.0056 16.3 0.0 0.014 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) CPT PF07931.7 KFX93902.1 - 0.015 14.9 0.0 0.12 12.0 0.0 2.2 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.1 KFX93902.1 - 0.019 14.7 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 KFX93902.1 - 0.026 14.8 0.0 0.15 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KFX93902.1 - 0.031 13.6 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ATP-synt_ab PF00006.20 KFX93902.1 - 0.059 12.8 0.1 0.23 10.9 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RuvB_N PF05496.7 KFX93902.1 - 0.089 11.8 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KFX93902.1 - 0.1 13.4 2.4 0.42 11.4 0.6 3.0 2 1 0 2 2 2 0 AAA domain PGAP1 PF07819.8 KFX93904.1 - 0.00025 20.7 0.0 0.00046 19.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KFX93904.1 - 0.0018 18.0 0.0 0.0035 17.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KFX93904.1 - 0.0051 16.1 0.0 0.0086 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KFX93904.1 - 0.052 13.4 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family AA_permease PF00324.16 KFX93912.1 - 4.6e-120 401.1 41.1 5.6e-120 400.9 28.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFX93912.1 - 2e-36 125.4 45.1 3.7e-36 124.5 31.3 1.3 1 1 0 1 1 1 1 Amino acid permease Ofd1_CTDD PF10637.4 KFX93913.1 - 3.7e-94 314.7 0.0 2e-89 299.2 0.0 2.2 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 KFX93913.1 - 1.6e-14 54.2 0.0 6.2e-14 52.3 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily GFA PF04828.9 KFX93914.1 - 2.1e-12 46.8 9.4 5.7e-08 32.5 0.2 3.1 2 1 1 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 KFX93914.1 - 0.0019 17.6 4.8 0.19 11.2 0.1 2.8 2 0 0 2 2 2 2 NADH pyrophosphatase zinc ribbon domain zf-CSL PF05207.8 KFX93914.1 - 0.003 17.0 7.5 1 8.9 0.1 3.5 3 0 0 3 3 3 2 CSL zinc finger zf-ribbon_3 PF13248.1 KFX93914.1 - 0.022 13.9 5.8 0.69 9.2 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.1 KFX93914.1 - 0.23 11.1 0.1 0.23 11.1 0.1 4.0 4 0 0 4 4 4 0 Nudix N-terminal DZR PF12773.2 KFX93914.1 - 0.77 9.6 9.1 0.97 9.3 0.0 3.2 4 0 0 4 4 4 0 Double zinc ribbon Pkinase PF00069.20 KFX93917.1 - 3.3e-64 216.5 0.0 4.6e-64 216.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX93917.1 - 1.9e-29 102.5 0.0 3.4e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KFX93917.1 - 3.7e-10 39.7 0.1 4.5e-09 36.2 0.0 2.5 2 0 0 2 2 2 1 FHA domain Kdo PF06293.9 KFX93917.1 - 0.0011 18.1 0.0 0.0026 16.8 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFX93917.1 - 0.025 13.5 0.0 0.053 12.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like p450 PF00067.17 KFX93918.1 - 5.5e-50 170.2 0.0 8.6e-50 169.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Diphthamide_syn PF01866.12 KFX93918.1 - 0.027 13.7 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative diphthamide synthesis protein RNase_T PF00929.19 KFX93920.1 - 3e-25 89.4 0.0 5.4e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Exonuclease Yippee-Mis18 PF03226.9 KFX93921.1 - 3.1e-05 23.9 0.1 7.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly BNR PF02012.15 KFX93922.1 - 1e-12 45.8 28.7 0.94 9.5 0.5 11.2 10 0 0 10 10 10 8 BNR/Asp-box repeat BNR_2 PF13088.1 KFX93922.1 - 2.6e-08 33.4 2.7 0.15 11.3 0.0 5.7 4 2 0 5 5 5 3 BNR repeat-like domain Gly-zipper_OmpA PF13436.1 KFX93923.1 - 0.04 13.5 2.6 0.062 12.9 1.8 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF1903 PF08991.5 KFX93935.1 - 5.5e-11 42.4 4.6 5.5e-11 42.4 3.2 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 KFX93935.1 - 0.028 14.3 1.4 0.028 14.3 1.0 1.5 2 0 0 2 2 2 0 CHCH domain DSPc PF00782.15 KFX93936.1 - 4e-22 78.2 0.1 4.4e-20 71.6 0.1 2.3 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFX93936.1 - 0.0018 17.6 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Suc_Fer-like PF06999.7 KFX93944.1 - 6.4e-32 111.4 0.2 2.2e-30 106.3 0.0 3.0 3 1 0 3 3 3 1 Sucrase/ferredoxin-like Drf_GBD PF06371.8 KFX93944.1 - 4.9e-15 55.3 2.4 4.9e-15 55.3 1.7 2.6 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain DRY_EERY PF09750.4 KFX93944.1 - 0.17 11.9 2.0 0.49 10.5 1.4 1.7 1 0 0 1 1 1 0 Alternative splicing regulator Glyco_hydro_43 PF04616.9 KFX93946.1 - 2.6e-64 217.0 2.8 3.2e-64 216.7 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DnaJ PF00226.26 KFX93954.1 - 6.6e-08 32.1 0.1 1.2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain zf-Di19 PF05605.7 KFX93954.1 - 0.012 15.7 1.5 0.012 15.7 1.1 3.8 2 2 2 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 KFX93954.1 - 0.25 11.7 0.1 0.25 11.7 0.1 4.6 4 1 1 5 5 5 0 C2H2-type zinc finger DZR PF12773.2 KFX93954.1 - 0.57 10.0 12.8 3.2 7.6 4.8 3.3 2 1 0 2 2 2 0 Double zinc ribbon zf-C2H2 PF00096.21 KFX93954.1 - 0.61 10.5 0.0 0.61 10.5 0.0 4.6 5 0 0 5 5 5 0 Zinc finger, C2H2 type SNARE PF05739.14 KFX93959.1 - 4.3e-11 42.3 5.4 4.3e-11 42.3 3.8 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KFX93959.1 - 4.2e-09 36.4 2.1 4.2e-09 36.4 1.4 2.4 2 0 0 2 2 2 1 Syntaxin Use1 PF09753.4 KFX93959.1 - 5.2e-07 29.3 9.2 7.9e-07 28.7 6.4 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Vac_Fusion PF02346.11 KFX93959.1 - 0.00088 18.6 1.3 0.04 13.3 0.0 2.8 3 0 0 3 3 3 1 Chordopoxvirus fusion protein Rifin_STEVOR PF02009.11 KFX93959.1 - 0.0048 16.5 10.4 0.013 15.1 5.6 2.1 1 1 1 2 2 2 1 Rifin/stevor family ODV-E18 PF10717.4 KFX93959.1 - 0.014 14.8 0.1 0.014 14.8 0.1 1.8 2 0 0 2 2 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF2659 PF10858.3 KFX93959.1 - 0.039 13.3 0.3 0.039 13.3 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2659) T2SF PF00482.18 KFX93959.1 - 0.06 13.2 3.9 0.28 11.0 1.7 2.6 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F SecG PF03840.9 KFX93959.1 - 0.069 12.8 1.7 0.17 11.6 1.2 1.7 1 0 0 1 1 1 0 Preprotein translocase SecG subunit MCPsignal PF00015.16 KFX93959.1 - 0.095 12.2 13.5 0.075 12.5 5.5 2.3 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain HHH_2 PF12826.2 KFX93959.1 - 0.11 12.4 0.4 0.24 11.3 0.2 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF3753 PF12575.3 KFX93959.1 - 0.15 11.8 3.0 0.32 10.8 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) 7tm_7 PF08395.7 KFX93959.1 - 0.18 10.7 2.3 0.39 9.6 0.0 2.0 2 0 0 2 2 2 0 7tm Chemosensory receptor PBP1_TM PF14812.1 KFX93959.1 - 0.48 10.7 0.0 0.48 10.7 0.0 2.5 3 0 0 3 3 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MitMem_reg PF13012.1 KFX93959.1 - 0.55 10.3 9.2 0.15 12.1 1.4 2.5 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function P12 PF12669.2 KFX93959.1 - 0.58 10.4 2.4 1.1 9.5 1.7 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family Syntaxin_2 PF14523.1 KFX93959.1 - 0.59 10.1 13.6 0.1 12.6 1.6 3.1 1 1 2 3 3 3 0 Syntaxin-like protein Spectrin PF00435.16 KFX93959.1 - 0.61 10.3 12.5 1.3 9.3 0.3 3.2 2 1 1 3 3 3 0 Spectrin repeat DUF2116 PF09889.4 KFX93959.1 - 0.99 9.2 3.1 3.2 7.6 2.1 1.8 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Allexi_40kDa PF05549.6 KFX93959.1 - 1.8 7.8 10.0 0.18 11.0 0.3 2.3 1 1 0 2 2 2 0 Allexivirus 40kDa protein ABC2_membrane_3 PF12698.2 KFX93959.1 - 1.9 7.4 3.8 3.4 6.6 2.6 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF4094 PF13334.1 KFX93959.1 - 2.6 8.4 11.6 0.12 12.7 1.5 3.2 1 1 3 4 4 4 0 Domain of unknown function (DUF4094) Memo PF01875.12 KFX93961.1 - 4.1e-79 265.3 0.0 4.7e-79 265.1 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein WD40 PF00400.27 KFX93962.1 - 5.3e-14 51.4 9.7 0.27 11.2 0.0 8.6 10 0 0 10 10 10 6 WD domain, G-beta repeat DUF325 PF03804.8 KFX93962.1 - 0.18 11.5 0.1 0.38 10.4 0.1 1.5 1 0 0 1 1 1 0 Viral domain of unknown function Rad4 PF03835.10 KFX93963.1 - 6.8e-15 54.7 2.2 1.4e-14 53.6 1.5 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 KFX93963.1 - 1.7e-12 47.5 3.8 3.7e-12 46.4 2.6 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Totivirus_coat PF05518.6 KFX93963.1 - 0.25 9.1 1.1 0.38 8.5 0.7 1.2 1 0 0 1 1 1 0 Totivirus coat protein Bcr-Abl_Oligo PF09036.5 KFX93966.1 - 0.052 13.5 0.2 0.073 13.0 0.1 1.2 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain Filament PF00038.16 KFX93967.1 - 0.0032 16.9 6.6 0.0032 16.9 4.6 5.8 4 1 1 5 5 5 3 Intermediate filament protein Reo_sigmaC PF04582.7 KFX93967.1 - 2 7.5 23.1 0.77 8.8 0.4 4.5 2 1 3 5 5 5 0 Reovirus sigma C capsid protein DUF4454 PF14628.1 KFX93977.1 - 0.045 13.3 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4454) KH_1 PF00013.24 KFX93978.1 - 1.2e-40 136.9 17.3 3.7e-15 55.3 0.7 3.7 4 0 0 4 4 4 3 KH domain KH_3 PF13014.1 KFX93978.1 - 5.8e-28 96.0 21.0 2.4e-10 39.7 0.9 4.4 5 0 0 5 5 5 3 KH domain KH_2 PF07650.12 KFX93978.1 - 1.2e-12 47.1 4.4 0.0019 17.7 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KFX93978.1 - 1.7e-08 33.9 5.4 0.09 12.4 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KFX93978.1 - 4.2e-06 26.4 1.1 0.89 9.4 0.0 3.7 3 0 0 3 3 3 3 NusA-like KH domain TIP49 PF06068.8 KFX93979.1 - 2.7e-186 619.0 0.4 3.2e-186 618.8 0.3 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KFX93979.1 - 8e-11 42.2 0.3 1.4e-06 28.5 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFX93979.1 - 9.4e-09 34.6 1.7 5.3e-06 25.6 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KFX93979.1 - 2.3e-06 27.7 0.0 0.0022 18.0 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 KFX93979.1 - 4.1e-05 23.3 0.2 0.03 14.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFX93979.1 - 4.3e-05 23.6 0.6 0.14 12.3 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_28 PF13521.1 KFX93979.1 - 8.8e-05 22.5 0.1 0.00019 21.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFX93979.1 - 9.4e-05 22.0 0.1 0.00028 20.5 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 KFX93979.1 - 0.00033 20.0 0.0 0.0011 18.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.21 KFX93979.1 - 0.00059 19.3 0.0 0.82 9.1 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 KFX93979.1 - 0.0015 17.7 0.1 0.0046 16.0 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 KFX93979.1 - 0.0034 16.8 0.1 0.0074 15.7 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KFX93979.1 - 0.0072 15.5 0.1 0.42 9.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KFX93979.1 - 0.0072 16.2 0.0 0.57 10.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 KFX93979.1 - 0.013 14.5 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 KFX93979.1 - 0.016 15.4 0.2 0.056 13.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KFX93979.1 - 0.023 13.8 0.3 0.11 11.5 0.0 2.0 2 0 0 2 2 2 0 KaiC MinE PF03776.9 KFX93979.1 - 0.051 13.0 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE Sigma54_activ_2 PF14532.1 KFX93979.1 - 0.056 13.4 0.0 1 9.4 0.0 2.6 2 1 1 3 3 3 0 Sigma-54 interaction domain AAA_17 PF13207.1 KFX93979.1 - 0.072 13.9 0.1 0.16 12.7 0.1 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 KFX93979.1 - 0.082 12.1 0.9 0.38 9.9 0.0 2.4 3 0 0 3 3 3 0 PhoH-like protein DnaB_C PF03796.10 KFX93979.1 - 0.12 11.2 0.0 0.27 10.0 0.0 1.6 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain HMG_box PF00505.14 KFX93980.1 - 5.1e-21 74.7 1.1 9.4e-21 73.8 0.8 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFX93980.1 - 1.2e-06 28.7 0.2 2.1e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 HMG-box domain GAF PF01590.21 KFX93980.1 - 0.1 12.7 1.1 0.28 11.3 0.1 2.1 2 0 0 2 2 2 0 GAF domain Glyco_hydro_63 PF03200.11 KFX93981.1 - 1e-08 33.5 4.2 7.4e-07 27.4 0.0 3.4 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase Rep_fac_C PF08542.6 KFX93982.1 - 1.3e-22 79.5 0.1 3.3e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KFX93982.1 - 1.6e-11 44.1 0.0 2.8e-11 43.3 0.0 1.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KFX93982.1 - 1.5e-06 28.4 0.1 3.3e-06 27.3 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFX93982.1 - 2.6e-05 24.3 0.5 0.00021 21.4 0.2 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KFX93982.1 - 0.00098 19.1 2.0 0.031 14.2 0.7 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 KFX93982.1 - 0.0018 18.1 0.1 0.0037 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 KFX93982.1 - 0.0089 16.0 0.2 0.26 11.3 0.2 2.5 1 1 0 1 1 1 1 Sigma-54 interaction domain ABC_tran PF00005.22 KFX93982.1 - 0.011 15.9 0.1 0.02 15.1 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 KFX93982.1 - 0.038 13.6 0.1 0.1 12.2 0.1 1.7 1 1 0 1 1 1 0 Archaeal ATPase DUF2861 PF11060.3 KFX93982.1 - 0.04 13.2 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2861) T4SS-DNA_transf PF02534.9 KFX93982.1 - 0.043 12.3 0.0 0.15 10.5 0.0 1.7 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Rad17 PF03215.10 KFX93982.1 - 0.057 12.0 0.0 0.079 11.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SNF2_N PF00176.18 KFX93982.1 - 0.088 11.5 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_29 PF13555.1 KFX93982.1 - 0.089 12.3 0.0 0.91 9.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_10 PF12846.2 KFX93982.1 - 0.12 11.8 0.1 2.1 7.7 0.0 2.2 1 1 1 2 2 2 0 AAA-like domain Shugoshin_N PF07558.6 KFX93983.1 - 2.9e-14 52.4 3.2 5.6e-14 51.5 2.2 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 KFX93983.1 - 1.7e-11 43.3 5.4 1.7e-11 43.3 3.8 3.1 3 0 0 3 3 3 1 Shugoshin C terminus DASH_Dad2 PF08654.5 KFX93984.1 - 2.5e-34 117.3 0.4 3.5e-34 116.8 0.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 DUF814 PF05670.8 KFX93986.1 - 1.3e-15 57.0 0.6 2.1e-15 56.3 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF814) Ribosomal_L3 PF00297.17 KFX93987.1 - 1.6e-34 119.5 4.2 1.8e-33 116.0 2.9 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 ABC2_membrane PF01061.19 KFX93989.1 - 1.8e-83 278.8 60.3 6.1e-47 159.5 16.0 3.4 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 KFX93989.1 - 3.7e-34 116.4 4.1 5.6e-32 109.4 0.0 3.3 4 0 0 4 4 3 2 CDR ABC transporter ABC_tran PF00005.22 KFX93989.1 - 6.4e-17 62.1 0.0 1.9e-16 60.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_25 PF13481.1 KFX93989.1 - 0.00012 21.5 0.0 0.00024 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 KFX93989.1 - 0.00016 20.8 41.3 0.0012 17.9 7.8 3.6 2 2 1 3 3 2 2 ABC-2 family transporter protein DUF258 PF03193.11 KFX93989.1 - 0.0003 20.0 0.0 0.00051 19.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFX93989.1 - 0.0024 17.3 0.3 0.0062 16.0 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 KFX93989.1 - 0.0028 16.8 0.0 0.082 12.1 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFX93989.1 - 0.0031 17.5 0.0 0.24 11.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KFX93989.1 - 0.0039 16.6 0.1 0.0066 15.9 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 KFX93989.1 - 0.0042 17.0 0.1 0.011 15.7 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFX93989.1 - 0.007 16.5 0.0 0.069 13.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KFX93989.1 - 0.015 15.1 0.0 0.06 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KFX93989.1 - 0.08 13.2 0.1 0.21 11.9 0.0 1.6 2 0 0 2 2 1 0 AAA domain CcmH PF03918.9 KFX93989.1 - 0.12 11.3 0.0 0.12 11.3 0.0 2.5 3 0 0 3 3 2 0 Cytochrome C biogenesis protein AAA_18 PF13238.1 KFX93989.1 - 0.26 11.5 0.0 0.6 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 KFX93989.1 - 0.67 8.9 0.0 1.8 7.5 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain DUF1129 PF06570.6 KFX93989.1 - 0.74 9.0 7.2 5.1 6.3 1.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) RNase_PH PF01138.16 KFX93990.1 - 9.8e-16 58.2 0.0 2.5e-15 56.9 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 SRP-alpha_N PF04086.8 KFX93991.1 - 4.1e-75 252.7 0.0 5.7e-75 252.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 KFX93991.1 - 3.3e-51 173.5 0.1 6e-51 172.6 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 KFX93991.1 - 5.9e-07 29.4 0.1 2.2e-06 27.6 0.1 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 KFX93991.1 - 2e-06 27.3 0.1 4.1e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 KFX93991.1 - 2.5e-06 26.4 0.1 5.9e-06 25.2 0.0 1.6 2 0 0 2 2 2 1 ArgK protein AAA_16 PF13191.1 KFX93991.1 - 0.00079 19.4 0.1 0.002 18.1 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 KFX93991.1 - 0.002 17.8 0.1 0.0047 16.6 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_NifH PF00142.13 KFX93991.1 - 0.015 14.5 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MMR_HSR1 PF01926.18 KFX93991.1 - 0.022 14.7 0.2 0.11 12.3 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.22 KFX93991.1 - 0.041 14.1 0.0 0.19 12.0 0.0 2.2 2 0 0 2 2 2 0 ABC transporter NTPase_1 PF03266.10 KFX93991.1 - 0.047 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 NTPase MipZ PF09140.6 KFX93991.1 - 0.053 12.5 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 ATPase MipZ CinA PF02464.12 KFX93991.1 - 0.17 11.3 1.6 0.17 11.3 0.1 1.8 2 0 0 2 2 2 0 Competence-damaged protein YIF1 PF03878.10 KFX93992.1 - 2.5e-74 249.4 0.5 3.9e-74 248.8 0.3 1.2 1 0 0 1 1 1 1 YIF1 AMP-binding PF00501.23 KFX93992.1 - 1.5e-71 240.9 0.0 2.1e-71 240.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX93992.1 - 1.6e-09 38.5 0.0 4.2e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Yip1 PF04893.12 KFX93992.1 - 0.00048 19.6 5.4 0.00048 19.6 3.7 1.6 2 0 0 2 2 2 1 Yip1 domain Aldedh PF00171.17 KFX93993.1 - 1.1e-122 409.6 0.0 1.4e-122 409.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HhH-GPD PF00730.20 KFX93994.1 - 2.1e-06 27.9 0.0 4.8e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein GATase_2 PF00310.16 KFX93995.1 - 2.4e-20 72.5 0.0 2.6e-15 56.0 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KFX93995.1 - 6.3e-14 52.0 0.0 1.9e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KFX93995.1 - 4.4e-13 49.0 0.0 1.1e-12 47.8 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 KFX93995.1 - 6.1e-12 45.3 0.0 1.3e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 KFX93995.1 - 0.0001 21.0 0.0 0.00017 20.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II ADH_zinc_N PF00107.21 KFX93995.1 - 0.025 14.1 0.1 0.77 9.3 0.0 3.0 3 0 0 3 3 3 0 Zinc-binding dehydrogenase TFIIS_C PF01096.13 KFX93996.1 - 8.1e-20 70.1 3.0 8.1e-20 70.1 2.1 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KFX93996.1 - 0.018 14.7 0.1 0.018 14.7 0.1 3.4 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Dynactin_p62 PF05502.8 KFX93996.1 - 0.084 11.6 0.7 0.086 11.5 0.5 1.2 1 0 0 1 1 1 0 Dynactin p62 family C1_3 PF07649.7 KFX93996.1 - 0.31 11.1 0.4 0.31 11.1 0.3 2.4 3 0 0 3 3 3 0 C1-like domain Zn_Tnp_IS1595 PF12760.2 KFX93996.1 - 5.6 6.8 8.2 5.2 6.9 0.2 2.8 2 2 0 2 2 2 0 Transposase zinc-ribbon domain C1_4 PF07975.7 KFX93996.1 - 8 6.5 7.8 4 7.5 0.8 2.9 3 1 0 3 3 3 0 TFIIH C1-like domain Ank_2 PF12796.2 KFX93997.1 - 1.1e-12 48.0 0.1 2.9e-12 46.7 0.1 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFX93997.1 - 8.6e-11 41.0 0.0 0.0019 17.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KFX93997.1 - 5.2e-09 35.4 0.1 0.013 15.6 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KFX93997.1 - 1.9e-07 31.4 0.1 1.1e-05 25.8 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX93997.1 - 0.0012 19.0 0.1 0.31 11.3 0.1 3.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Rdx PF10262.4 KFX94001.1 - 5.9e-28 96.6 0.0 1e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 Rdx family G-gamma PF00631.17 KFX94001.1 - 5.7e-24 83.6 0.0 1.1e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 GGL domain Glyco_hydro_31 PF01055.21 KFX94002.1 - 2.1e-22 79.5 0.1 2.3e-22 79.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 AMP-binding PF00501.23 KFX94008.1 - 4.7e-82 275.5 0.0 7e-82 275.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KFX94008.1 - 3.6e-60 202.9 0.0 5.5e-60 202.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KFX94008.1 - 2.2e-11 43.8 0.0 5.7e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 KFX94008.1 - 5.2e-11 42.4 0.0 1.4e-10 41.0 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFX94008.1 - 3.8e-08 32.3 0.0 1.7e-07 30.2 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 KFX94008.1 - 1.7e-06 28.9 0.7 7.7e-06 26.7 0.0 2.5 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain RmlD_sub_bind PF04321.12 KFX94008.1 - 5e-05 22.3 0.2 0.00028 19.8 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain ADH_zinc_N PF00107.21 KFX94009.1 - 5.6e-25 87.3 0.0 8.9e-25 86.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PhoH PF02562.11 KFX94009.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein DUF3425 PF11905.3 KFX94010.1 - 4e-20 72.0 2.3 8.8e-20 70.9 1.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KFX94010.1 - 9.9e-05 22.2 13.0 0.00084 19.2 7.8 2.5 1 1 1 2 2 2 2 bZIP transcription factor SPO22 PF08631.5 KFX94010.1 - 0.07 12.2 0.2 0.12 11.3 0.2 1.3 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like bZIP_2 PF07716.10 KFX94010.1 - 0.18 11.6 12.0 5.1 6.9 5.2 2.7 2 0 0 2 2 2 0 Basic region leucine zipper DUF837 PF05769.6 KFX94010.1 - 0.31 10.5 4.8 0.54 9.7 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF837) Latarcin PF10279.4 KFX94010.1 - 2.2 8.5 4.8 2.3 8.4 2.0 2.1 2 1 0 2 2 2 0 Latarcin precursor Peptidase_M50 PF02163.17 KFX94011.1 - 0.15 10.9 1.3 0.21 10.5 0.9 1.3 1 0 0 1 1 1 0 Peptidase family M50 DUF3712 PF12505.3 KFX94012.1 - 7e-30 103.6 0.8 1.6e-29 102.5 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) DUF805 PF05656.9 KFX94012.1 - 0.04 13.7 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) ESSS PF10183.4 KFX94012.1 - 0.074 13.4 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF2236 PF09995.4 KFX94013.1 - 5.6e-36 124.0 0.5 7.9e-36 123.5 0.4 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) AMP-binding PF00501.23 KFX94014.1 - 2e-73 247.1 0.0 2.6e-73 246.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX94014.1 - 1.1e-13 51.9 0.1 2.1e-13 50.9 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CrtC PF07143.6 KFX94015.1 - 1.8e-18 66.8 0.0 4.2e-18 65.7 0.0 1.5 1 1 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) Glyco_hydro_114 PF03537.8 KFX94031.1 - 7.3e-25 86.5 0.3 1.5e-24 85.5 0.2 1.6 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Abhydrolase_6 PF12697.2 KFX94031.1 - 2.1e-21 76.8 0.1 3.5e-21 76.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX94031.1 - 8.8e-07 28.7 0.0 1.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFX94031.1 - 9.9e-07 28.5 0.0 2e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 KFX94031.1 - 7.2e-05 22.4 0.0 0.0013 18.3 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 KFX94031.1 - 0.086 12.2 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DUF2726 PF10881.3 KFX94031.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) Glyco_hydro_6 PF01341.12 KFX94032.1 - 3.2e-93 312.4 1.5 3.9e-93 312.1 1.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Fungal_trans PF04082.13 KFX94033.1 - 5.8e-18 64.7 0.3 9.5e-18 64.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX94033.1 - 1.6e-05 24.7 12.5 2.6e-05 24.0 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LMBR1 PF04791.11 KFX94034.1 - 8.6e-16 57.5 13.7 9.1e-15 54.1 5.9 2.3 1 1 0 2 2 2 2 LMBR1-like membrane protein Anemone_cytotox PF06369.7 KFX94034.1 - 0.16 11.3 0.2 0.34 10.3 0.1 1.5 1 0 0 1 1 1 0 Sea anemone cytotoxic protein Claudin_2 PF13903.1 KFX94034.1 - 0.52 9.9 18.9 0.29 10.7 1.2 4.3 4 2 0 4 4 4 0 PMP-22/EMP/MP20/Claudin tight junction CPSF_A PF03178.10 KFX94035.1 - 2.9e-83 279.6 0.0 9.2e-83 277.9 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 KFX94035.1 - 8e-06 24.2 0.0 0.00015 20.0 0.0 2.2 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term Phage_holin_3 PF05106.7 KFX94036.1 - 0.015 15.2 1.3 0.046 13.7 0.9 1.8 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) MFS_1 PF07690.11 KFX94037.1 - 2.6e-24 85.6 38.1 4.1e-23 81.6 26.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Lon_C PF05362.8 KFX94037.1 - 0.056 12.7 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 Lon protease (S16) C-terminal proteolytic domain DUF4381 PF14316.1 KFX94038.1 - 6.2 6.9 5.9 2.5 8.2 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF972 PF06156.8 KFX94038.1 - 8.9 6.7 16.1 29 5.0 1.8 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Pyr_redox_2 PF07992.9 KFX94039.1 - 4.3e-29 101.8 0.0 9.2e-29 100.7 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX94039.1 - 2.6e-15 56.5 2.2 8.6e-14 51.7 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 KFX94039.1 - 2.5e-12 46.2 0.0 8.8e-12 44.4 0.0 2.0 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 KFX94039.1 - 1.3e-11 44.9 0.1 0.00018 21.6 0.0 3.3 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 KFX94039.1 - 3.5e-05 24.0 0.0 0.00011 22.4 0.0 1.9 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.1 KFX94039.1 - 0.0001 21.3 0.1 0.25 10.2 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Rieske_2 PF13806.1 KFX94039.1 - 0.0024 17.5 0.0 0.012 15.2 0.0 2.2 3 0 0 3 3 3 1 Rieske-like [2Fe-2S] domain NAD_binding_9 PF13454.1 KFX94039.1 - 0.0035 17.1 0.6 3.7 7.2 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding DUF1188 PF06690.6 KFX94039.1 - 0.0048 16.0 0.1 0.0083 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) HI0933_like PF03486.9 KFX94039.1 - 0.0096 14.4 2.2 0.16 10.3 0.0 3.0 3 1 0 3 3 3 1 HI0933-like protein Trp_halogenase PF04820.9 KFX94039.1 - 0.011 14.3 0.3 0.63 8.6 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase DUF1479 PF07350.7 KFX94041.1 - 9.1e-31 106.7 0.1 1e-30 106.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Glyco_transf_28 PF03033.15 KFX94042.1 - 9e-19 67.6 0.0 3.7e-18 65.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KFX94042.1 - 3e-06 26.0 0.0 5.2e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KFX94042.1 - 0.0002 21.0 0.0 0.00052 19.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Cortex-I_coil PF09304.5 KFX94043.1 - 6.4e-05 22.9 27.5 0.0059 16.6 2.7 3.7 2 2 1 3 3 3 2 Cortexillin I, coiled coil Filament PF00038.16 KFX94043.1 - 0.00084 18.8 39.2 0.0022 17.5 8.8 3.6 1 1 2 3 3 3 2 Intermediate filament protein Fib_alpha PF08702.5 KFX94043.1 - 0.0077 16.3 6.1 0.0077 16.3 4.2 3.6 2 1 1 3 3 3 1 Fibrinogen alpha/beta chain family Tropomyosin PF00261.15 KFX94043.1 - 0.0077 15.3 5.6 0.0077 15.3 3.9 4.0 1 1 2 3 3 3 1 Tropomyosin IncA PF04156.9 KFX94043.1 - 0.25 10.9 37.1 0.038 13.5 10.3 3.4 1 1 0 2 2 2 0 IncA protein WEMBL PF05701.6 KFX94043.1 - 0.42 9.0 40.4 0.52 8.7 21.7 2.1 1 1 1 2 2 2 0 Weak chloroplast movement under blue light ADIP PF11559.3 KFX94043.1 - 0.42 10.5 40.9 0.34 10.7 3.4 4.2 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.7 KFX94043.1 - 0.93 9.7 6.6 12 6.1 0.0 4.0 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 KFX94043.1 - 3.3 7.5 14.0 1.2 8.9 1.3 3.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) TMA7 PF09072.5 KFX94043.1 - 3.7 8.0 10.2 21 5.6 1.7 3.1 2 0 0 2 2 2 0 Translation machinery associated TMA7 Laminin_II PF06009.7 KFX94043.1 - 5.7 6.6 14.0 0.073 12.8 0.9 3.3 1 1 1 2 2 2 0 Laminin Domain II Fork_head PF00250.13 KFX94044.1 - 3.1e-21 75.2 0.1 6.5e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 KFX94044.1 - 0.00059 19.8 0.0 0.0018 18.3 0.0 1.8 1 0 0 1 1 1 1 FHA domain HEAT PF02985.17 KFX94050.1 - 0.01 15.8 2.3 24 5.3 0.1 5.1 5 0 0 5 5 5 0 HEAT repeat Acetyltransf_3 PF13302.1 KFX94051.1 - 1.8e-19 70.3 0.0 2.5e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX94051.1 - 6.7e-06 26.0 0.0 1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family AhpC-TSA PF00578.16 KFX94052.1 - 2.2e-30 104.9 0.0 5.1e-30 103.7 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 KFX94052.1 - 3e-21 75.5 0.0 9.4e-20 70.6 0.0 2.1 1 1 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 KFX94052.1 - 0.0019 18.1 0.0 0.0042 16.9 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.7 KFX94052.1 - 0.003 17.0 0.0 0.0039 16.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) Glyco_hydro_88 PF07470.8 KFX94054.1 - 9.9e-64 215.4 0.6 1.2e-63 215.2 0.4 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Prenyltrans_2 PF13249.1 KFX94054.1 - 0.003 17.9 1.0 0.13 12.6 0.0 2.0 2 1 1 3 3 3 2 Prenyltransferase-like Sugar_tr PF00083.19 KFX94055.1 - 1.2e-91 307.5 28.5 1.4e-91 307.3 19.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX94055.1 - 3.4e-22 78.6 45.8 8.6e-17 60.8 11.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.14 KFX94056.1 - 2.7e-27 95.7 0.0 4.5e-27 95.0 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFX94056.1 - 9.7e-10 37.8 4.9 2.7e-08 33.1 0.9 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX94056.1 - 3.9e-08 33.2 0.3 9.9e-08 31.9 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFX94056.1 - 5e-06 26.8 0.6 0.016 15.5 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFX94056.1 - 2.8e-05 23.2 0.4 0.00015 20.8 0.3 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KFX94056.1 - 3.6e-05 22.7 0.1 7.7e-05 21.7 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KFX94056.1 - 4.8e-05 22.0 0.4 0.0022 16.5 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 KFX94056.1 - 0.00014 21.6 1.1 0.57 9.9 0.0 3.5 4 0 0 4 4 4 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KFX94056.1 - 0.00048 20.0 0.5 0.00083 19.2 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFX94056.1 - 0.00061 18.9 0.1 0.0011 18.1 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 KFX94056.1 - 0.0024 17.9 0.3 0.014 15.5 0.2 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFX94056.1 - 0.0027 16.6 0.6 0.0058 15.5 0.2 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 KFX94056.1 - 0.0048 15.5 0.6 0.61 8.6 0.1 2.9 3 0 0 3 3 3 1 Tryptophan halogenase ApbA PF02558.11 KFX94056.1 - 0.012 15.1 0.2 0.02 14.3 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.19 KFX94056.1 - 0.025 13.6 0.0 6 5.8 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 KFX94056.1 - 0.039 13.6 0.2 0.086 12.4 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KFX94056.1 - 0.058 12.7 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_43 PF04616.9 KFX94057.1 - 6.2e-43 146.9 4.6 8.8e-43 146.4 3.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 BAT2_N PF07001.6 KFX94058.1 - 0.0071 16.7 4.5 0.014 15.7 3.1 1.5 1 0 0 1 1 1 1 BAT2 N-terminus DUF1122 PF06557.6 KFX94063.1 - 0.16 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1122) DUF1304 PF06993.7 KFX94064.1 - 3.3e-39 133.1 3.5 3.6e-39 132.9 2.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) DsbD_2 PF13386.1 KFX94064.1 - 0.47 10.1 6.5 0.6 9.8 4.5 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region Ank_2 PF12796.2 KFX94065.1 - 1e-17 64.2 0.0 1.3e-07 31.8 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFX94065.1 - 3.4e-15 54.6 0.0 0.0045 17.0 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.25 KFX94065.1 - 1e-14 53.4 0.3 4.6e-05 23.0 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KFX94065.1 - 9e-10 38.4 0.2 0.00097 19.3 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFX94065.1 - 1.2e-08 35.1 0.0 0.0012 19.3 0.0 2.9 2 1 0 2 2 2 2 Ankyrin repeats (many copies) DUF2370 PF10176.4 KFX94065.1 - 1.3 8.3 5.4 8.3 5.6 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) HET PF06985.6 KFX94066.1 - 5.5e-20 71.9 1.6 9e-16 58.2 0.1 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) FB_lectin PF07367.6 KFX94066.1 - 0.11 12.0 0.1 0.32 10.5 0.0 1.7 2 0 0 2 2 2 0 Fungal fruit body lectin APC8 PF04049.8 KFX94069.1 - 1.3e-31 109.1 0.0 3.4e-31 107.8 0.0 1.7 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 KFX94069.1 - 1.6e-22 78.0 1.0 9.2e-05 21.8 0.0 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 KFX94069.1 - 1.9e-22 78.6 9.0 4.9e-08 32.5 0.6 5.7 3 1 3 6 6 6 5 TPR repeat TPR_2 PF07719.12 KFX94069.1 - 7.2e-18 62.9 7.4 0.0033 17.2 0.0 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFX94069.1 - 9.3e-14 50.6 15.7 0.049 14.2 0.1 9.4 7 2 3 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.1 KFX94069.1 - 8.8e-12 44.7 11.6 0.0009 19.1 1.0 6.5 3 1 4 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 KFX94069.1 - 4.4e-10 38.6 2.4 0.45 10.4 0.0 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFX94069.1 - 4.8e-09 35.3 10.1 0.19 11.5 0.1 6.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFX94069.1 - 8.2e-09 35.9 9.8 0.053 14.2 0.2 6.5 5 1 2 7 7 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KFX94069.1 - 7.5e-08 32.3 5.4 0.33 11.1 0.0 5.9 4 1 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KFX94069.1 - 4.4e-07 30.1 6.6 0.074 13.4 0.0 6.3 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFX94069.1 - 5e-07 29.4 3.1 7.9 6.9 0.0 6.6 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFX94069.1 - 3.1e-05 23.7 7.7 0.093 12.5 0.0 5.1 4 1 1 5 5 4 1 Tetratricopeptide repeat DUF3856 PF12968.2 KFX94069.1 - 0.013 15.3 1.1 0.31 10.8 0.1 2.9 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_6 PF13174.1 KFX94069.1 - 0.21 12.1 10.5 4.9 7.8 0.1 6.1 7 0 0 7 7 6 0 Tetratricopeptide repeat Ank_2 PF12796.2 KFX94071.1 - 1.3e-41 140.8 7.0 7.7e-14 51.8 0.1 4.8 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFX94071.1 - 1.1e-28 97.5 6.8 1.2e-05 24.8 0.0 7.7 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 KFX94071.1 - 6.2e-26 90.2 0.8 7.5e-08 32.6 0.1 5.2 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX94071.1 - 9e-24 81.1 4.5 0.006 16.7 0.0 9.0 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.1 KFX94071.1 - 2.9e-23 81.3 4.5 6e-07 29.5 0.1 6.0 2 1 4 7 7 7 5 Ankyrin repeats (many copies) NACHT PF05729.7 KFX94071.1 - 5.6e-08 32.6 0.0 3.6e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KFX94071.1 - 1.7e-05 24.9 0.0 8e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain ketoacyl-synt PF00109.21 KFX94073.1 - 2.8e-79 266.2 0.0 7.7e-79 264.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Carn_acyltransf PF00755.15 KFX94073.1 - 7e-74 248.9 0.0 9.7e-74 248.5 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Acyl_transf_1 PF00698.16 KFX94073.1 - 6.5e-57 193.2 1.6 1.3e-56 192.2 1.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KFX94073.1 - 3.4e-53 180.7 0.2 6.2e-53 179.8 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 KFX94073.1 - 6e-44 149.8 0.2 6e-44 149.8 0.2 1.9 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.17 KFX94073.1 - 6e-39 132.5 0.3 2e-38 130.8 0.2 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KFX94073.1 - 3.6e-37 127.8 0.4 3.6e-37 127.8 0.3 2.6 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.21 KFX94073.1 - 1.9e-19 69.4 1.0 2.9e-18 65.6 0.3 3.0 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 KFX94073.1 - 5.3e-15 55.6 0.0 2.4e-14 53.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX94073.1 - 1.1e-12 47.9 0.0 3.7e-12 46.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KFX94073.1 - 1.3e-12 48.6 0.0 1.7e-11 45.0 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Ubie_methyltran PF01209.13 KFX94073.1 - 1.3e-09 37.5 0.0 4.4e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KFX94073.1 - 2.5e-08 33.6 0.0 2.7e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX94073.1 - 1.1e-07 32.4 0.0 1.7e-06 28.5 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX94073.1 - 1.2e-07 32.1 0.0 8.4e-07 29.4 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 KFX94073.1 - 2e-07 31.1 0.3 4.7e-07 29.9 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_16 PF10294.4 KFX94073.1 - 0.00087 18.7 0.0 0.0027 17.1 0.0 1.8 1 0 0 1 1 1 1 Putative methyltransferase DREV PF05219.7 KFX94073.1 - 0.015 14.2 0.0 0.038 12.8 0.0 1.6 1 0 0 1 1 1 0 DREV methyltransferase Glyco_tranf_2_3 PF13641.1 KFX94074.1 - 2.1e-23 83.3 0.0 2.9e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KFX94074.1 - 4.1e-23 82.0 2.4 4.1e-23 82.0 1.7 2.1 2 0 0 2 2 2 1 Glycosyl transferase family group 2 MFS_1 PF07690.11 KFX94075.1 - 4.9e-40 137.3 36.5 4.9e-40 137.3 25.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Trypan_PARP PF05887.6 KFX94077.1 - 0.002 17.9 11.8 0.0032 17.2 8.2 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) rRNA_processing PF08524.6 KFX94077.1 - 0.26 11.0 6.0 0.5 10.1 4.2 1.5 1 1 0 1 1 1 0 rRNA processing Cellulase PF00150.13 KFX94078.1 - 4.5e-45 154.0 0.0 5.9e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TOBE_3 PF12857.2 KFX94078.1 - 0.15 11.9 0.0 2.4 8.0 0.0 2.2 2 0 0 2 2 2 0 TOBE-like domain Glyco_hydro_7 PF00840.15 KFX94079.1 - 7.1e-72 242.1 0.3 8.2e-72 241.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Cellulase PF00150.13 KFX94080.1 - 1.4e-49 168.8 0.4 1.7e-49 168.5 0.2 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AMP-binding PF00501.23 KFX94081.1 - 1.5e-63 214.6 0.0 2e-63 214.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KFX94081.1 - 5.4e-23 81.2 0.1 8.7e-23 80.6 0.1 1.3 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.1 KFX94081.1 - 2e-07 31.8 0.1 4.7e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 KFX94081.1 - 0.13 10.7 0.1 0.34 9.3 0.0 1.7 2 0 0 2 2 2 0 GH3 auxin-responsive promoter DUF2867 PF11066.3 KFX94082.1 - 1.4e-34 118.9 0.4 1.5e-33 115.6 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2867) Ank PF00023.25 KFX94090.1 - 0.034 13.9 0.3 0.12 12.2 0.2 1.9 1 1 0 1 1 1 0 Ankyrin repeat Ank_5 PF13857.1 KFX94090.1 - 0.071 13.3 0.2 0.098 12.9 0.1 1.4 1 1 0 1 1 1 0 Ankyrin repeats (many copies) Rad60-SLD PF11976.3 KFX94102.1 - 4.6e-17 61.4 0.0 6.7e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like MOSC_N PF03476.11 KFX94102.1 - 0.027 14.1 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 MOSC N-terminal beta barrel domain ubiquitin PF00240.18 KFX94102.1 - 0.039 13.3 0.0 0.075 12.4 0.0 1.5 1 1 0 1 1 1 0 Ubiquitin family GATase_4 PF13230.1 KFX94104.1 - 2.2e-14 52.8 0.0 2.6e-12 45.9 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KFX94104.1 - 6.6e-09 35.8 0.0 1.5e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KFX94104.1 - 1.6e-06 27.1 0.0 0.0001 21.1 0.0 2.4 2 0 0 2 2 2 2 Glutamine amidotransferases class-II Cation_efflux PF01545.16 KFX94105.1 - 1.6e-30 106.2 10.9 2.1e-30 105.8 7.6 1.1 1 0 0 1 1 1 1 Cation efflux family DUF1418 PF07214.7 KFX94105.1 - 0.18 11.4 0.8 0.43 10.2 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) PHO4 PF01384.15 KFX94106.1 - 0.012 14.2 0.0 0.03 12.9 0.0 1.6 2 0 0 2 2 2 0 Phosphate transporter family DUF2370 PF10176.4 KFX94106.1 - 0.17 11.2 1.2 3.1 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) DUF2956 PF11169.3 KFX94106.1 - 4 7.4 5.2 5.6 6.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) PIG-Y PF15159.1 KFX94106.1 - 8.3 6.7 9.9 46 4.3 6.8 2.1 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Ebp2 PF05890.7 KFX94108.1 - 7.2e-48 163.2 31.0 8e-48 163.0 21.5 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 DUF416 PF04222.7 KFX94108.1 - 0.23 10.6 2.0 0.33 10.0 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF416) DUF4647 PF15504.1 KFX94108.1 - 2.3 6.9 11.3 2.8 6.6 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DDHD PF02862.12 KFX94108.1 - 4.8 6.9 8.0 6.3 6.5 5.6 1.3 1 0 0 1 1 1 0 DDHD domain GvpL_GvpF PF06386.6 KFX94108.1 - 7.2 6.1 6.7 5.2 6.5 3.9 1.3 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Ecm29 PF13001.2 KFX94109.1 - 6.3e-136 453.7 0.1 1.9e-135 452.2 0.0 1.8 2 0 0 2 2 2 1 Proteasome stabiliser HEAT PF02985.17 KFX94109.1 - 1e-08 34.5 2.9 5.7 7.2 0.0 7.7 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.1 KFX94109.1 - 2.4e-07 30.9 17.8 0.091 13.0 0.0 10.0 8 3 2 10 10 10 2 HEAT repeats HEAT_EZ PF13513.1 KFX94109.1 - 1.7e-06 28.3 11.8 0.21 12.1 0.1 9.4 10 1 1 11 11 11 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KFX94109.1 - 0.00075 19.8 0.1 0.19 12.1 0.0 4.6 4 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region CRAL_TRIO PF00650.15 KFX94121.1 - 3.1e-36 124.2 0.0 4.5e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFX94121.1 - 2.9e-08 33.7 0.6 6.3e-08 32.6 0.1 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KFX94121.1 - 2.4e-06 27.5 0.0 7.8e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Serum_albumin PF00273.15 KFX94121.1 - 0.16 11.3 0.4 0.26 10.6 0.3 1.2 1 0 0 1 1 1 0 Serum albumin family Prefoldin PF02996.12 KFX94122.1 - 1.3e-31 108.7 0.1 2.7e-31 107.6 0.0 1.5 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 KFX94122.1 - 0.007 16.1 0.5 0.099 12.4 0.0 2.4 2 1 1 3 3 3 1 Prefoldin subunit MAD PF05557.8 KFX94122.1 - 0.031 12.3 1.3 0.092 10.8 0.1 1.8 2 0 0 2 2 2 0 Mitotic checkpoint protein SlyX PF04102.7 KFX94122.1 - 0.06 13.7 0.8 8.2 6.8 0.1 2.6 3 0 0 3 3 3 0 SlyX DUF4201 PF13870.1 KFX94122.1 - 0.12 11.8 1.4 2 7.8 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF3112 PF11309.3 KFX94123.1 - 1.6e-50 170.9 15.4 1.4e-47 161.4 2.8 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) Zn_clus PF00172.13 KFX94124.1 - 9.5e-07 28.6 9.6 1.8e-06 27.7 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 KFX94125.1 - 2.5e-18 66.8 0.2 2.9e-18 66.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX94125.1 - 2.3e-07 30.6 0.1 2.7e-07 30.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Pkinase PF00069.20 KFX94137.1 - 2.2e-58 197.4 0.0 3.2e-58 196.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX94137.1 - 4.4e-30 104.6 0.0 6.6e-29 100.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KFX94137.1 - 0.047 12.4 0.0 0.064 12.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Cro PF09048.5 KFX94137.1 - 0.11 12.1 0.1 0.62 9.7 0.0 2.1 2 0 0 2 2 2 0 Cro Kdo PF06293.9 KFX94137.1 - 0.18 10.8 0.1 0.32 10.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kelch_5 PF13854.1 KFX94138.1 - 4.6e-07 29.6 3.6 1.8e-06 27.7 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Glyco_hydro_62 PF03664.8 KFX94139.1 - 1.9e-149 496.1 14.2 2.6e-149 495.7 9.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.13 KFX94139.1 - 2.7e-10 39.7 16.8 2.7e-10 39.7 11.6 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain HC2 PF07382.6 KFX94139.1 - 0.12 12.2 21.6 0.25 11.1 15.0 1.5 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Ycf1 PF05758.7 KFX94139.1 - 0.22 9.1 2.6 0.31 8.7 1.8 1.1 1 0 0 1 1 1 0 Ycf1 APG6 PF04111.7 KFX94139.1 - 0.98 8.3 9.7 2 7.4 6.7 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 NARP1 PF12569.3 KFX94139.1 - 8.3 5.0 19.5 13 4.4 13.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Kelch_3 PF13415.1 KFX94142.1 - 6.5e-27 93.0 14.5 4e-08 33.2 0.0 7.0 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_4 PF13418.1 KFX94142.1 - 1.3e-23 82.4 12.1 2.5e-06 27.1 0.0 6.6 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 KFX94142.1 - 7.5e-19 67.0 3.7 0.0003 20.8 0.0 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_5 PF13854.1 KFX94142.1 - 1.8e-17 62.8 3.9 1.5e-06 27.9 0.0 6.4 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 KFX94142.1 - 1.5e-14 53.2 0.1 1.3e-05 24.5 0.0 5.5 5 0 0 5 5 5 3 Kelch motif DUF4110 PF13422.1 KFX94142.1 - 3.3e-13 49.2 0.1 3.3e-13 49.2 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_2 PF07646.10 KFX94142.1 - 5.3e-12 45.0 2.7 0.15 11.8 0.0 6.3 6 1 0 6 6 6 3 Kelch motif Abhydrolase_6 PF12697.2 KFX94143.1 - 4.8e-11 42.9 0.0 1.4e-10 41.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX94143.1 - 6.3e-08 32.4 0.0 6.6e-07 29.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX94143.1 - 9.3e-08 31.9 0.0 1.8e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFX94143.1 - 0.016 14.3 0.0 0.11 11.6 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 KFX94143.1 - 0.046 13.5 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S10 PF00450.17 KFX94143.1 - 0.16 11.1 0.6 8.4 5.4 0.0 2.4 3 0 0 3 3 3 0 Serine carboxypeptidase CENP-K PF11802.3 KFX94144.1 - 1.8e-08 33.9 2.2 0.0005 19.3 0.0 2.9 2 1 1 3 3 3 2 Centromere-associated protein K Macoilin PF09726.4 KFX94144.1 - 0.62 8.2 7.4 0.049 11.9 0.4 1.9 2 0 0 2 2 2 0 Transmembrane protein BAR PF03114.13 KFX94144.1 - 3.2 7.2 8.1 2.7 7.4 3.0 2.4 2 1 0 2 2 2 0 BAR domain DUF4446 PF14584.1 KFX94144.1 - 4 7.2 6.4 2.9 7.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF2458 PF10454.4 KFX94144.1 - 6.7 6.5 10.0 0.54 10.1 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2458) IncA PF04156.9 KFX94144.1 - 7.1 6.1 15.0 0.64 9.5 0.7 2.6 2 1 1 3 3 3 0 IncA protein Rsc14 PF08586.5 KFX94145.1 - 0.038 14.4 0.6 6.1 7.3 0.1 2.1 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit APH PF01636.18 KFX94151.1 - 8.9e-09 35.4 0.0 1.4e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX94151.1 - 1.2e-06 28.2 0.0 2.2e-06 27.4 0.0 1.5 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF1679 PF07914.6 KFX94151.1 - 0.021 13.4 0.0 0.029 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) GMC_oxred_C PF05199.8 KFX94152.1 - 1.1e-30 106.8 0.0 1.8e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KFX94152.1 - 7.9e-26 90.8 0.0 8.2e-25 87.5 0.0 2.4 1 1 0 2 2 2 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 KFX94152.1 - 0.00019 21.5 0.1 0.063 13.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFX94152.1 - 0.0011 18.8 0.0 0.032 14.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFX94152.1 - 0.0015 17.5 1.4 1.2 7.9 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX94152.1 - 0.0063 16.5 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 KFX94152.1 - 0.046 13.3 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KFX94152.1 - 0.094 11.5 1.2 0.36 9.6 0.3 2.0 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 KFX94152.1 - 0.1 11.4 0.4 0.15 10.9 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein CFEM PF05730.6 KFX94153.1 - 1.8e-14 53.2 9.2 3.4e-14 52.4 6.4 1.4 1 0 0 1 1 1 1 CFEM domain Peroxidase_2 PF01328.12 KFX94154.1 - 3.7e-11 42.2 3.4 4.2e-10 38.7 2.4 2.0 1 1 0 1 1 1 1 Peroxidase, family 2 Pkinase PF00069.20 KFX94155.1 - 3.2e-27 95.3 0.0 4.2e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX94155.1 - 3.9e-19 68.7 0.0 6.1e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HABP4_PAI-RBP1 PF04774.10 KFX94159.1 - 2 8.9 10.2 0.12 12.8 2.7 2.3 2 1 0 2 2 2 0 Hyaluronan / mRNA binding family adh_short PF00106.20 KFX94160.1 - 1.8e-26 93.0 1.0 2.5e-26 92.6 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX94160.1 - 4e-23 82.4 0.1 4.9e-23 82.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX94160.1 - 2.2e-13 50.2 0.3 3e-13 49.8 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFX94160.1 - 0.0028 17.1 0.3 0.0092 15.4 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFX94160.1 - 0.056 12.3 0.1 0.077 11.8 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KFX94160.1 - 0.13 11.1 0.1 0.9 8.4 0.1 2.2 1 1 1 2 2 2 0 Male sterility protein F-box-like PF12937.2 KFX94161.1 - 4.1e-05 23.2 0.0 0.0001 21.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX94161.1 - 0.0016 18.0 0.3 0.0054 16.3 0.2 2.0 1 0 0 1 1 1 1 F-box domain Peptidase_S10 PF00450.17 KFX94162.1 - 7.4e-112 374.5 0.0 8.9e-112 374.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KFX94162.1 - 0.0018 18.1 0.0 0.02 14.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family RNA_Me_trans PF04252.8 KFX94163.1 - 1.1e-47 161.9 0.0 1.4e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Mito_fiss_reg PF05308.6 KFX94167.1 - 0.015 14.6 1.7 0.017 14.5 1.1 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator Telomere_Sde2 PF13019.1 KFX94170.1 - 1.3e-67 226.5 0.6 2.3e-67 225.7 0.4 1.4 1 0 0 1 1 1 1 Telomere stability and silencing S10_plectin PF03501.10 KFX94171.1 - 2e-28 98.1 0.1 2.7e-28 97.6 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Ribosomal_L15e PF00827.12 KFX94172.1 - 6.4e-90 299.8 8.7 1.3e-89 298.7 6.1 1.5 1 0 0 1 1 1 1 Ribosomal L15 DUF4551 PF15087.1 KFX94172.1 - 0.24 9.7 3.9 0.38 9.0 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) zf-HIT PF04438.11 KFX94173.1 - 1.3e-09 37.4 10.1 2e-09 36.9 7.0 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 KFX94173.1 - 0.0066 16.3 9.5 0.011 15.5 6.6 1.3 1 0 0 1 1 1 1 MYND finger zf-B_box PF00643.19 KFX94173.1 - 0.052 13.4 6.0 0.084 12.7 4.1 1.2 1 0 0 1 1 1 0 B-box zinc finger Tnp_zf-ribbon_2 PF13842.1 KFX94173.1 - 1.9 8.9 9.8 2.5 8.5 6.3 1.6 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon GTP_EFTU PF00009.22 KFX94190.1 - 3.3e-56 189.7 0.0 5e-56 189.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KFX94190.1 - 2.4e-37 127.0 0.0 6.3e-37 125.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFX94190.1 - 1.4e-15 57.1 3.4 1.4e-15 57.1 2.4 2.1 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFX94190.1 - 0.00066 19.6 0.2 0.0024 17.8 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 KFX94190.1 - 0.002 17.7 1.5 0.002 17.7 1.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 zf-MIZ PF02891.15 KFX94191.1 - 8e-11 41.2 0.3 1.5e-10 40.4 0.2 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PINIT PF14324.1 KFX94191.1 - 0.00025 21.1 0.0 0.00053 20.0 0.0 1.6 1 0 0 1 1 1 1 PINIT domain zf-Nse PF11789.3 KFX94191.1 - 0.0077 15.7 0.2 0.034 13.6 0.1 2.2 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit LexA_DNA_bind PF01726.11 KFX94191.1 - 0.02 14.4 0.0 3.3 7.3 0.0 2.7 2 0 0 2 2 2 0 LexA DNA binding domain Methyltransf_16 PF10294.4 KFX94192.1 - 1.6e-23 83.0 0.0 5.7e-22 77.9 0.0 2.7 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_23 PF13489.1 KFX94192.1 - 0.00042 20.0 0.0 0.00081 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFX94192.1 - 0.00055 19.1 0.0 0.00087 18.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 KFX94192.1 - 0.0047 16.4 0.0 0.018 14.5 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 KFX94192.1 - 0.005 16.2 0.1 0.019 14.3 0.1 1.7 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KFX94192.1 - 0.01 16.4 0.0 0.02 15.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_S24e PF01282.14 KFX94193.1 - 6.4e-33 112.3 0.0 1e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Zn_clus PF00172.13 KFX94194.1 - 2.9e-07 30.2 6.9 5e-07 29.5 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.16 KFX94195.1 - 7.5e-35 120.4 0.0 1.2e-34 119.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 KFX94195.1 - 1.7e-15 56.3 0.0 3.1e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX94195.1 - 1.1e-10 41.3 0.0 2.6e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX94195.1 - 4.7e-08 32.7 0.0 1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CENP-B_dimeris PF09026.5 KFX94196.1 - 2.1 8.6 7.5 3.1 8.0 5.2 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.8 KFX94196.1 - 5.3 4.6 8.2 6 4.4 5.7 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF3115 PF11312.3 KFX94203.1 - 3.5e-35 121.3 0.0 5.6e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Alpha_L_fucos PF01120.12 KFX94204.1 - 1.6e-26 93.0 0.0 1.1e-25 90.2 0.0 2.1 1 1 0 1 1 1 1 Alpha-L-fucosidase Nop16 PF09420.5 KFX94205.1 - 2.8e-53 180.3 9.0 3.3e-53 180.1 6.3 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 EHN PF06441.7 KFX94205.1 - 0.91 9.4 3.6 0.69 9.8 1.0 1.9 2 1 0 2 2 2 0 Epoxide hydrolase N terminus Mito_carr PF00153.22 KFX94207.1 - 2.8e-52 174.3 1.0 3.9e-17 61.7 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.13 KFX94207.1 - 6.8e-34 116.9 0.4 1.7e-33 115.5 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX94207.1 - 1.1e-05 25.2 9.1 1.1e-05 25.2 6.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KFX94208.1 - 6.6e-31 107.4 0.0 9.5e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX94208.1 - 3.8e-14 53.0 0.0 4.9e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX94208.1 - 3.4e-11 43.1 0.0 4.8e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KFX94208.1 - 0.0015 18.3 0.1 0.0041 16.8 0.1 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 KFX94208.1 - 0.009 14.9 0.1 0.022 13.6 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DHDPS PF00701.17 KFX94209.1 - 5.5e-44 149.9 0.0 6.8e-44 149.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MFS_1 PF07690.11 KFX94210.1 - 7.3e-37 126.8 33.0 4.2e-36 124.3 24.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MR_MLE_C PF13378.1 KFX94211.1 - 4.6e-19 68.4 1.2 5.5e-19 68.1 0.1 1.7 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KFX94211.1 - 2.8e-12 46.9 1.4 1.6e-11 44.5 0.1 2.4 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KFX94211.1 - 0.00045 20.1 0.2 0.002 18.0 0.2 2.1 1 1 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain SRP54 PF00448.17 KFX94212.1 - 1.8e-06 27.5 0.0 2.6e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PRK PF00485.13 KFX94212.1 - 2.2e-06 27.3 0.0 3.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 KFX94212.1 - 9.1e-05 23.2 0.0 0.00021 22.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFX94212.1 - 0.00072 19.5 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain cobW PF02492.14 KFX94212.1 - 0.0024 17.3 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 KFX94212.1 - 0.0055 17.0 0.1 0.012 15.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 KFX94212.1 - 0.012 15.2 0.1 0.039 13.5 0.1 1.8 1 1 1 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KFX94212.1 - 0.017 14.7 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.9 KFX94212.1 - 0.025 13.6 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.1 KFX94212.1 - 0.028 13.9 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_31 PF13614.1 KFX94212.1 - 0.029 14.3 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KFX94212.1 - 0.031 14.5 0.0 0.048 13.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter ArgK PF03308.11 KFX94212.1 - 0.031 13.0 0.0 0.051 12.3 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Thymidylate_kin PF02223.12 KFX94212.1 - 0.031 13.6 0.0 0.081 12.2 0.0 1.7 1 0 0 1 1 1 0 Thymidylate kinase AAA_30 PF13604.1 KFX94212.1 - 0.034 13.7 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFX94212.1 - 0.041 13.7 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KFX94212.1 - 0.045 13.4 0.1 0.2 11.4 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 KFX94212.1 - 0.048 13.8 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 KFX94212.1 - 0.058 12.9 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 KFX94212.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KFX94212.1 - 0.11 12.2 0.0 0.44 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KFX94212.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain NDUF_B4 PF07225.7 KFX94213.1 - 0.054 13.2 0.1 0.061 13.1 0.1 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Hexokinase_2 PF03727.11 KFX94231.1 - 1.1e-14 54.2 0.3 1.2e-14 54.1 0.2 1.0 1 0 0 1 1 1 1 Hexokinase GAF_2 PF13185.1 KFX94238.1 - 1.9e-07 31.6 0.0 3.5e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 KFX94238.1 - 0.0012 18.9 0.4 0.0027 17.8 0.0 1.7 2 0 0 2 2 2 1 GAF domain DLH PF01738.13 KFX94239.1 - 8.4e-25 87.3 0.0 2.6e-24 85.7 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFX94239.1 - 1.3e-08 34.7 0.0 1.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFX94239.1 - 0.0061 15.8 0.0 0.031 13.4 0.0 2.1 3 0 0 3 3 3 1 Prolyl oligopeptidase family DAP10 PF07213.6 KFX94240.1 - 0.0044 16.7 0.6 0.012 15.3 0.4 1.7 1 0 0 1 1 1 1 DAP10 membrane protein CcmD PF04995.9 KFX94240.1 - 0.0097 15.6 1.1 0.019 14.6 0.7 1.4 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) CFEM PF05730.6 KFX94240.1 - 0.011 15.5 5.7 0.021 14.6 4.0 1.5 1 0 0 1 1 1 0 CFEM domain TMEM154 PF15102.1 KFX94240.1 - 0.017 14.8 4.3 0.058 13.1 3.0 1.9 1 1 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.1 KFX94240.1 - 0.018 15.4 0.1 0.1 12.9 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.20 KFX94242.1 - 2.8e-63 213.4 0.0 3.8e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX94242.1 - 2.7e-25 88.9 0.0 3.5e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX94242.1 - 1.3e-07 30.9 0.0 6.2e-07 28.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFX94242.1 - 0.0019 18.0 0.0 0.0063 16.2 0.0 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX94242.1 - 0.044 13.3 0.0 0.066 12.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase PLA2_B PF01735.13 KFX94243.1 - 5.2e-24 84.2 0.0 1.7e-23 82.5 0.0 1.8 1 1 0 1 1 1 1 Lysophospholipase catalytic domain RE_NgoPII PF09521.5 KFX94243.1 - 0.11 11.2 0.0 0.21 10.3 0.0 1.4 1 0 0 1 1 1 0 NgoPII restriction endonuclease PRANC PF09372.5 KFX94244.1 - 0.13 12.2 0.0 0.34 10.9 0.0 1.7 1 0 0 1 1 1 0 PRANC domain Ank_2 PF12796.2 KFX94246.1 - 2.2e-14 53.5 0.0 2.9e-05 24.3 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFX94246.1 - 1.2e-10 40.6 0.0 2 8.3 0.0 6.1 5 1 1 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 KFX94246.1 - 3.4e-10 39.1 0.1 0.33 11.3 0.0 6.6 7 0 0 7 7 7 2 Ankyrin repeat Ank_4 PF13637.1 KFX94246.1 - 7.8e-10 39.0 0.2 0.00057 20.3 0.0 5.5 3 1 3 6 6 6 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX94246.1 - 7.3e-05 22.8 0.0 0.87 9.9 0.0 5.0 5 0 0 5 5 5 1 Ankyrin repeats (many copies) MFS_1 PF07690.11 KFX94247.1 - 6.6e-29 100.7 38.2 1.9e-28 99.2 26.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KFX94247.1 - 9.5e-20 70.3 16.6 1.4e-19 69.7 11.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KFX94247.1 - 6.9e-17 61.1 10.7 6.9e-17 61.1 7.4 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter Glyco_hydro_10 PF00331.15 KFX94248.1 - 6.8e-66 222.4 3.2 2.3e-53 181.2 0.6 3.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 ADH_zinc_N_2 PF13602.1 KFX94248.1 - 1.2e-08 35.8 0.4 3.5e-08 34.3 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF1944 PF09175.5 KFX94248.1 - 0.0089 15.6 0.1 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1944) Glyco_hydro_11 PF00457.12 KFX94249.1 - 2.7e-65 219.1 21.7 4.6e-65 218.4 15.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 MFS_1 PF07690.11 KFX94249.1 - 1.6e-15 56.7 51.2 2.3e-09 36.4 12.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyclin_N PF00134.18 KFX94250.1 - 0.0028 17.2 0.0 0.037 13.5 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain DAO PF01266.19 KFX94251.1 - 5.2e-47 160.4 0.0 6.1e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX94251.1 - 2.3e-07 30.7 0.0 1.5e-06 28.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFX94251.1 - 0.00011 21.2 0.0 0.0041 16.0 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KFX94251.1 - 0.0002 21.3 0.0 0.012 15.4 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFX94251.1 - 0.00029 20.9 0.0 0.0034 17.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFX94251.1 - 0.00029 20.0 0.0 0.00044 19.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.13 KFX94251.1 - 0.0011 18.9 0.0 0.0025 17.7 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_9 PF13454.1 KFX94251.1 - 0.0021 17.8 0.0 0.052 13.3 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KFX94251.1 - 0.004 17.5 0.0 0.0087 16.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFX94251.1 - 0.013 14.3 0.0 0.068 12.0 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 KFX94251.1 - 0.027 14.5 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 KFX94251.1 - 0.037 13.8 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.9 KFX94251.1 - 0.044 12.2 0.0 6.3 5.1 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein ApbA PF02558.11 KFX94251.1 - 0.053 12.9 0.0 0.096 12.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_4 PF07993.7 KFX94252.1 - 3.8e-30 104.6 0.0 8.6e-30 103.4 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 KFX94252.1 - 2e-22 79.1 0.0 4.5e-22 78.0 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 KFX94252.1 - 5e-09 35.9 0.0 1.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KFX94252.1 - 1.3e-06 28.5 0.0 4.9e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site adh_short PF00106.20 KFX94252.1 - 0.083 12.7 0.1 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.8 KFX94253.1 - 7e-26 90.9 0.1 8.7e-26 90.6 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX94253.1 - 2e-17 63.7 0.2 3e-17 63.2 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KFX94253.1 - 2.8e-05 23.2 0.3 4.2e-05 22.6 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 KFX94253.1 - 0.0023 16.6 0.1 0.029 13.0 0.1 2.4 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KFX94253.1 - 0.0024 17.3 0.2 0.012 15.0 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KFX94253.1 - 0.007 16.6 0.8 0.013 15.7 0.2 1.7 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KFX94253.1 - 0.0077 15.3 0.4 0.099 11.7 0.3 2.2 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DapB_N PF01113.15 KFX94253.1 - 0.014 15.3 0.1 0.041 13.8 0.1 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 KFX94253.1 - 0.017 14.0 0.2 0.059 12.2 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein Aldedh PF00171.17 KFX94258.1 - 1.9e-93 313.3 2.7 2.3e-93 313.0 1.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AAA_2 PF07724.9 KFX94258.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) p450 PF00067.17 KFX94275.1 - 5e-57 193.4 0.0 7.4e-57 192.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 KFX94275.1 - 1.7e-15 56.5 0.0 4.9e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX94275.1 - 1.1e-08 34.8 10.6 2.2e-08 33.8 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3431 PF11913.3 KFX94275.1 - 0.14 11.5 0.7 5.3 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3431) FAA_hydrolase PF01557.13 KFX94276.1 - 1.5e-46 158.5 0.0 2.1e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 KFX94276.1 - 9.4e-27 93.1 0.0 4.9e-26 90.8 0.0 2.0 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Methyltransf_16 PF10294.4 KFX94277.1 - 3.7e-40 137.2 0.0 5.3e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KFX94277.1 - 7.8e-07 29.6 0.0 2.8e-06 27.8 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.8 KFX94277.1 - 8.4e-06 25.1 0.0 1.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KFX94277.1 - 1.3e-05 24.6 0.0 2.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KFX94277.1 - 0.00087 19.3 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 KFX94277.1 - 0.00095 18.2 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_25 PF13649.1 KFX94277.1 - 0.0012 19.1 0.0 0.0074 16.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX94277.1 - 0.0025 17.5 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX94277.1 - 0.012 16.0 0.0 0.03 14.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 KFX94277.1 - 0.12 13.1 0.0 0.62 10.9 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase domain DUF938 PF06080.7 KFX94277.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Cys_Met_Meta_PP PF01053.15 KFX94279.1 - 2.1e-148 493.7 0.0 2.4e-148 493.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KFX94279.1 - 2.1e-11 43.3 0.1 3.8e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KFX94279.1 - 5.3e-11 42.1 0.5 9.5e-11 41.3 0.4 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 KFX94279.1 - 7.7e-07 28.1 0.1 1.8e-06 26.9 0.1 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KFX94279.1 - 4.8e-05 22.6 0.0 0.00011 21.4 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase GDC-P PF02347.11 KFX94279.1 - 0.002 16.9 0.0 0.0032 16.2 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 KFX94279.1 - 0.0098 14.2 0.2 0.013 13.8 0.1 1.3 1 1 0 1 1 1 1 Methionine gamma-lyase zf-C2H2_jaz PF12171.3 KFX94293.1 - 2.3e-08 33.9 6.2 0.49 10.6 0.0 5.1 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KFX94293.1 - 3.6e-05 23.7 45.0 0.044 14.1 1.6 7.0 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2 PF00096.21 KFX94293.1 - 0.0006 20.0 11.5 0.00096 19.3 2.8 6.7 7 0 0 7 7 7 3 Zinc finger, C2H2 type zf-met PF12874.2 KFX94293.1 - 0.0007 19.7 15.3 0.68 10.2 0.1 5.4 7 0 0 7 7 7 3 Zinc-finger of C2H2 type DUF4066 PF13278.1 KFX94294.1 - 8.3e-26 90.2 0.0 1.2e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KFX94294.1 - 2.1e-13 49.9 0.0 3.3e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family TPR_12 PF13424.1 KFX94297.1 - 1.5e-06 28.0 0.9 0.24 11.3 0.2 4.3 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFX94297.1 - 0.00065 19.3 3.2 0.65 9.6 0.0 3.8 3 1 0 3 3 3 2 TPR repeat Apc3 PF12895.2 KFX94297.1 - 0.0024 17.9 0.5 0.007 16.4 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Cyt-b5 PF00173.23 KFX94298.1 - 2e-05 24.2 0.0 2.4e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ricin_B_lectin PF00652.17 KFX94307.1 - 6.6e-20 71.3 0.6 1.2e-19 70.5 0.4 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Melibiase PF02065.13 KFX94307.1 - 1.9e-16 59.7 0.1 2.8e-14 52.6 0.2 2.1 2 0 0 2 2 2 2 Melibiase RicinB_lectin_2 PF14200.1 KFX94307.1 - 0.014 15.7 0.1 0.18 12.1 0.0 2.7 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.9 KFX94307.1 - 0.016 14.6 2.0 2.7 7.3 0.1 2.8 1 1 1 2 2 2 0 Cytolethal distending toxin A/C family Glyco_transf_8 PF01501.15 KFX94308.1 - 1.5e-11 44.1 0.0 3.9e-11 42.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 RNase_H PF00075.19 KFX94309.1 - 7.4e-16 58.6 0.0 1.2e-15 58.0 0.0 1.2 1 0 0 1 1 1 1 RNase H Esterase_phd PF10503.4 KFX94310.1 - 9.8e-21 74.0 0.7 1.3e-20 73.5 0.5 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KFX94310.1 - 8e-13 48.1 0.5 1.4e-12 47.2 0.1 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFX94310.1 - 2.7e-08 33.6 0.2 3.9e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX94310.1 - 5.9e-06 26.3 0.4 3.9e-05 23.6 0.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFX94310.1 - 0.0001 21.8 1.1 0.001 18.5 0.7 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase PF00756.15 KFX94310.1 - 0.00049 19.5 0.6 0.0043 16.5 0.4 2.0 1 1 0 1 1 1 1 Putative esterase FSH1 PF03959.8 KFX94310.1 - 0.0016 17.9 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 KFX94310.1 - 0.0019 17.8 0.2 0.0024 17.4 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KFX94310.1 - 0.004 16.7 0.1 0.0068 15.9 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2235 PF09994.4 KFX94310.1 - 0.12 11.6 0.1 0.52 9.6 0.0 1.7 1 1 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) AXE1 PF05448.7 KFX94310.1 - 0.14 10.6 0.1 0.3 9.5 0.0 1.5 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) MR_MLE_C PF13378.1 KFX94311.1 - 1e-34 118.8 0.1 2.5e-34 117.5 0.0 1.7 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 KFX94311.1 - 6.8e-20 71.2 0.0 1.4e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 KFX94311.1 - 1.1e-08 35.5 0.0 3.4e-08 33.9 0.0 1.9 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain SBP56 PF05694.6 KFX94312.1 - 1.1e-06 27.4 0.0 0.00012 20.7 0.0 3.1 1 1 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.4 KFX94312.1 - 0.0085 15.2 0.1 1.6 7.6 0.1 2.7 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller SGL PF08450.7 KFX94312.1 - 0.027 13.8 0.1 1.8 7.8 0.0 2.8 2 1 1 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region Nup160 PF11715.3 KFX94312.1 - 0.034 12.2 0.0 0.049 11.7 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 NHL PF01436.16 KFX94312.1 - 0.13 12.2 1.9 3.9 7.6 0.0 3.3 4 0 0 4 4 4 0 NHL repeat Cupin_1 PF00190.17 KFX94313.1 - 5e-29 100.5 0.0 1.7e-13 50.2 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 KFX94313.1 - 3.3e-23 80.9 1.1 1.3e-11 43.8 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KFX94313.1 - 1.9e-08 33.5 0.0 0.0036 16.6 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.2 KFX94313.1 - 7.6e-07 28.9 0.1 0.014 14.9 0.0 2.6 2 1 1 3 3 3 2 Cupin AraC_binding PF02311.14 KFX94313.1 - 1.5e-05 24.7 0.3 0.041 13.5 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain 2OG-FeII_Oxy_5 PF13759.1 KFX94313.1 - 0.038 14.2 0.2 79 3.6 0.0 3.7 2 2 2 4 4 4 0 Putative 2OG-Fe(II) oxygenase p450 PF00067.17 KFX94315.1 - 3.1e-75 253.4 0.0 4e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC_membrane_3 PF13748.1 KFX94315.1 - 0.0048 15.9 0.0 0.0095 14.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region Methyltransf_31 PF13847.1 KFX94316.1 - 4.6e-24 84.7 0.0 6.5e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX94316.1 - 1.3e-23 83.3 0.0 2.4e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX94316.1 - 2.5e-16 59.5 0.0 1e-15 57.5 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 KFX94316.1 - 5.9e-16 58.6 0.0 8.2e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX94316.1 - 1.4e-15 57.7 0.0 2.2e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX94316.1 - 2.2e-14 53.6 0.0 3.8e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX94316.1 - 3.1e-14 53.2 0.0 5e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX94316.1 - 8.5e-10 38.2 0.0 1.3e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KFX94316.1 - 1.5e-09 37.9 0.0 2.2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KFX94316.1 - 7.9e-08 32.0 0.0 1.9e-07 30.8 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 KFX94316.1 - 2.5e-06 26.7 0.0 3.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_24 PF13578.1 KFX94316.1 - 5.7e-06 27.1 0.0 1.1e-05 26.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KFX94316.1 - 6.9e-06 25.5 0.0 1.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Fibrillarin PF01269.12 KFX94316.1 - 0.00044 19.2 0.0 0.00065 18.6 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin Methyltransf_4 PF02390.12 KFX94316.1 - 0.0018 17.3 0.0 0.014 14.4 0.0 2.1 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_29 PF03141.11 KFX94316.1 - 0.0034 15.8 0.0 0.0044 15.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase FtsJ PF01728.14 KFX94316.1 - 0.0054 16.7 0.0 0.0078 16.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase GCD14 PF08704.5 KFX94316.1 - 0.0072 15.8 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.8 KFX94316.1 - 0.01 14.9 0.2 0.019 14.0 0.0 1.4 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Nol1_Nop2_Fmu PF01189.12 KFX94316.1 - 0.016 14.6 0.0 0.041 13.2 0.0 1.6 1 1 0 1 1 1 0 NOL1/NOP2/sun family ADH_zinc_N PF00107.21 KFX94316.1 - 0.023 14.2 0.1 0.16 11.5 0.1 2.1 1 1 0 1 1 1 0 Zinc-binding dehydrogenase RrnaAD PF00398.15 KFX94316.1 - 0.028 13.4 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.6 KFX94316.1 - 0.028 13.1 0.0 0.047 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TrkA_N PF02254.13 KFX94316.1 - 0.038 13.9 0.1 0.76 9.7 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain Methyltransf_32 PF13679.1 KFX94316.1 - 0.039 13.6 0.0 0.086 12.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain DOT1 PF08123.8 KFX94316.1 - 0.052 12.8 0.0 1.2 8.4 0.0 2.1 1 1 1 2 2 2 0 Histone methylation protein DOT1 Methyltransf_8 PF05148.10 KFX94316.1 - 0.065 12.8 0.1 0.26 10.8 0.1 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase Octopine_DH PF02317.12 KFX94317.1 - 1.8e-39 134.8 0.0 2.6e-39 134.3 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NAD_Gly3P_dh_N PF01210.18 KFX94317.1 - 1.2e-11 44.6 0.0 1.9e-11 43.9 0.0 1.5 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 KFX94317.1 - 3.5e-05 24.1 0.0 6.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.9 KFX94317.1 - 0.00069 19.5 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFX94317.1 - 0.0024 16.7 0.0 0.0037 16.1 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KFX94317.1 - 0.0036 17.3 0.0 0.011 15.7 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KFX94317.1 - 0.0042 17.1 0.0 0.0068 16.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFX94317.1 - 0.0058 15.1 0.0 0.012 14.1 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 KFX94317.1 - 0.0079 15.2 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.11 KFX94317.1 - 0.015 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 KFX94317.1 - 0.039 12.8 0.0 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 KFX94317.1 - 0.048 12.4 0.0 0.066 12.0 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.14 KFX94317.1 - 0.11 11.6 0.0 0.84 8.7 0.0 2.2 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KFX94317.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Rossmann-like PF10727.4 KFX94317.1 - 0.11 12.1 0.1 0.46 10.2 0.1 2.0 1 1 0 1 1 1 0 Rossmann-like domain MFS_1 PF07690.11 KFX94318.1 - 6.8e-48 163.1 36.5 6.8e-48 163.1 25.3 2.7 3 0 0 3 3 3 1 Major Facilitator Superfamily Ferric_reduct PF01794.14 KFX94318.1 - 7.7e-16 58.3 12.0 7.7e-16 58.3 8.3 2.8 3 0 0 3 3 3 1 Ferric reductase like transmembrane component Sugar_tr PF00083.19 KFX94318.1 - 6e-14 51.4 18.4 6e-14 51.4 12.8 2.6 2 0 0 2 2 2 1 Sugar (and other) transporter FAD_binding_8 PF08022.7 KFX94318.1 - 1.8e-12 47.0 0.0 3.3e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 FAD-binding domain MFS_3 PF05977.8 KFX94318.1 - 3.7e-05 22.0 2.1 3.7e-05 22.0 1.4 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector NAD_binding_6 PF08030.7 KFX94318.1 - 0.00093 19.1 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Peptidase_M24 PF00557.19 KFX94319.1 - 1.4e-35 122.7 0.4 2e-35 122.2 0.3 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 PGA2 PF07543.7 KFX94319.1 - 0.09 12.5 0.7 0.21 11.3 0.5 1.6 1 0 0 1 1 1 0 Protein trafficking PGA2 PP_kinase_N PF13089.1 KFX94319.1 - 0.11 12.5 0.0 0.51 10.4 0.0 2.1 3 0 0 3 3 3 0 Polyphosphate kinase N-terminal domain S-methyl_trans PF02574.11 KFX94320.1 - 1.2e-17 64.2 0.0 1.7e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Peripla_BP_4 PF13407.1 KFX94320.1 - 0.0033 16.7 0.0 0.0045 16.3 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Peripla_BP_6 PF13458.1 KFX94320.1 - 0.054 12.8 0.1 0.075 12.3 0.1 1.1 1 0 0 1 1 1 0 Periplasmic binding protein MR_MLE_C PF13378.1 KFX94320.1 - 0.069 13.1 0.1 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Enolase C-terminal domain-like PGM_PMM_I PF02878.11 KFX94320.1 - 0.18 11.2 0.1 0.31 10.5 0.1 1.3 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I SNF5 PF04855.7 KFX94324.1 - 0.076 12.4 0.2 0.091 12.2 0.2 1.1 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 bZIP_1 PF00170.16 KFX94331.1 - 0.0065 16.3 14.5 0.074 13.0 10.0 2.0 1 1 0 1 1 1 1 bZIP transcription factor DivIC PF04977.10 KFX94331.1 - 0.12 11.8 0.2 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.10 KFX94331.1 - 6.4 6.6 13.1 1.5 8.6 0.2 2.2 2 0 0 2 2 2 0 Basic region leucine zipper EF-hand_1 PF00036.27 KFX94332.1 - 2.4e-17 60.8 2.3 7.5e-07 28.0 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 KFX94332.1 - 1.4e-16 60.3 0.4 1.6e-09 37.7 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFX94332.1 - 2.6e-14 51.7 2.4 9.3e-06 25.1 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 KFX94332.1 - 2.1e-13 49.6 5.1 1.4e-08 34.2 0.2 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 KFX94332.1 - 8.3e-09 34.4 5.1 1.4e-05 24.2 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 KFX94332.1 - 0.0093 15.8 0.0 0.061 13.2 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.4 KFX94332.1 - 0.052 13.5 0.2 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KFX94332.1 - 0.072 12.8 0.0 0.74 9.5 0.0 2.3 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Hexapep PF00132.19 KFX94333.1 - 2.8e-15 55.0 12.0 1.6e-08 33.6 0.3 3.6 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KFX94333.1 - 2.7e-14 52.4 16.3 6e-07 28.9 0.1 3.3 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.13 KFX94333.1 - 1e-09 38.1 14.7 2.8e-09 36.7 10.2 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mac PF12464.3 KFX94333.1 - 4.1e-07 29.9 0.0 8.1e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase DUF3295 PF11702.3 KFX94334.1 - 4.9e-56 190.7 26.9 5.4e-26 91.6 6.1 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3295) DUF1752 PF08550.5 KFX94334.1 - 0.003 17.1 9.4 0.0059 16.1 6.5 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) GalP_UDP_transf PF01087.17 KFX94343.1 - 1.2e-70 237.2 0.1 1.3e-68 230.7 0.1 2.2 2 0 0 2 2 2 2 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 KFX94343.1 - 1.4e-56 190.6 0.1 2.5e-56 189.7 0.1 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 KFX94343.1 - 0.0026 18.2 0.0 0.066 13.7 0.0 2.3 2 0 0 2 2 2 1 HIT domain DIE2_ALG10 PF04922.7 KFX94344.1 - 1.1e-44 153.0 0.0 1.6e-44 152.4 0.0 1.2 1 0 0 1 1 1 1 DIE2/ALG10 family Isochorismatase PF00857.15 KFX94346.1 - 6.6e-22 78.2 0.0 1e-21 77.6 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Voltage_CLC PF00654.15 KFX94348.1 - 6.3e-92 308.3 20.7 6.3e-92 308.3 14.3 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel PTPLA PF04387.9 KFX94353.1 - 3.1e-43 147.0 7.0 3.1e-43 147.0 4.8 1.5 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA HMGL-like PF00682.14 KFX94354.1 - 1.9e-54 184.8 0.0 2.8e-54 184.2 0.0 1.2 1 0 0 1 1 1 1 HMGL-like PS_Dcarbxylase PF02666.10 KFX94355.1 - 2.6e-51 173.7 0.0 3.4e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.3 KFX94355.1 - 0.0059 16.2 0.1 0.017 14.7 0.0 1.7 2 0 0 2 2 2 1 Phophatidylserine decarboxylase Glyco_hydro_2_C PF02836.12 KFX94355.1 - 0.073 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain p450 PF00067.17 KFX94356.1 - 3.3e-51 174.2 0.0 3.8e-51 174.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KFX94357.1 - 4.7e-39 134.0 30.5 3.2e-32 111.6 16.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 KFX94359.1 - 3.8e-07 29.2 0.1 7e-07 28.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX94359.1 - 3.6e-05 23.5 8.8 7e-05 22.6 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VCBS PF13517.1 KFX94360.1 - 4.6e-38 129.3 75.8 6.1e-10 39.3 4.4 8.0 3 3 4 7 7 7 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KFX94360.1 - 1.2e-20 72.5 82.6 0.0027 17.3 0.8 10.9 11 0 0 11 11 11 9 FG-GAP repeat Lipase_GDSL PF00657.17 KFX94360.1 - 2.3e-17 63.6 1.4 4.5e-17 62.6 0.3 1.9 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.3 KFX94360.1 - 3.9e-15 55.7 26.4 0.097 12.1 0.1 9.3 4 2 5 9 9 9 8 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_2 PF13472.1 KFX94360.1 - 7e-12 45.8 0.5 2.4e-11 44.1 0.0 2.2 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 KFX94360.1 - 0.048 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DMA PF03474.9 KFX94360.1 - 0.26 11.1 0.0 0.45 10.3 0.0 1.4 1 0 0 1 1 1 0 DMRTA motif adh_short PF00106.20 KFX94362.1 - 5.7e-18 65.3 0.2 8e-18 64.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX94362.1 - 2.2e-09 37.4 0.0 2.8e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX94362.1 - 1.8e-07 31.0 0.0 2.6e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFX94362.1 - 0.0063 16.5 0.0 0.02 14.9 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding MFS_1 PF07690.11 KFX94364.1 - 2.6e-46 157.9 36.8 2.6e-46 157.9 25.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX94364.1 - 3.9e-12 45.4 33.1 2.1e-11 43.0 23.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KFX94364.1 - 0.00021 19.6 5.1 0.00031 19.0 2.9 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 KFX94364.1 - 0.0092 14.0 5.6 0.013 13.5 1.1 2.3 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family ABM PF03992.11 KFX94365.1 - 0.0015 18.4 0.5 0.25 11.3 0.2 2.4 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Mito_carr PF00153.22 KFX94375.1 - 3.4e-45 151.6 11.5 6.1e-17 61.1 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pyridoxal_deC PF00282.14 KFX94376.1 - 2.3e-70 236.9 0.0 3.2e-70 236.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KFX94376.1 - 0.0005 18.9 0.0 0.00077 18.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.15 KFX94376.1 - 0.012 14.2 0.4 0.18 10.3 0.0 2.2 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain Metallothio PF00131.15 KFX94380.1 - 5.4 6.9 24.9 0.57 10.0 4.4 2.9 3 0 0 3 3 3 0 Metallothionein Metallothio_2 PF01439.13 KFX94380.1 - 7.9 7.1 25.8 0.32 11.5 0.7 2.7 2 1 0 2 2 2 0 Metallothionein SH3_3 PF08239.6 KFX94382.1 - 0.0037 17.4 0.0 0.006 16.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial SH3 domain Fungal_trans PF04082.13 KFX94384.1 - 6.2e-26 90.8 0.1 6.2e-26 90.8 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX94384.1 - 7.1e-08 32.2 13.7 1.3e-07 31.4 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_TAF50 PF03326.8 KFX94384.1 - 0.003 16.5 15.8 0.0047 15.9 10.9 1.2 1 0 0 1 1 1 1 Herpesvirus transcription activation factor (transactivator) MR_MLE_C PF13378.1 KFX94385.1 - 4.5e-20 71.6 0.0 9.6e-20 70.6 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KFX94385.1 - 1.8e-11 44.4 0.0 4.5e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KFX94385.1 - 4.6e-09 36.2 0.0 7.8e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain adh_short PF00106.20 KFX94386.1 - 4.4e-27 95.0 3.0 6.1e-27 94.5 2.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX94386.1 - 3.5e-22 79.3 0.0 4.2e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX94386.1 - 5.5e-09 35.9 1.8 8.3e-09 35.3 1.3 1.2 1 0 0 1 1 1 1 KR domain PCI PF01399.22 KFX94387.1 - 3.3e-20 72.3 0.0 5.9e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 PCI domain DDRGK PF09756.4 KFX94387.1 - 0.0015 17.9 0.2 0.0022 17.4 0.2 1.3 1 0 0 1 1 1 1 DDRGK domain PCI_Csn8 PF10075.4 KFX94387.1 - 0.091 12.5 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 HTH_Crp_2 PF13545.1 KFX94387.1 - 0.18 11.6 1.3 0.52 10.1 0.1 2.3 2 2 1 3 3 3 0 Crp-like helix-turn-helix domain Phosphodiest PF01663.17 KFX94392.1 - 2.1e-16 60.1 0.6 1.2e-15 57.7 0.6 1.9 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KFX94392.1 - 9.4e-06 25.0 0.0 2.3e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 KFX94392.1 - 1.3e-05 24.7 1.2 2e-05 24.1 0.8 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF2628 PF10947.3 KFX94392.1 - 0.61 9.9 15.9 0.021 14.6 1.4 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2628) zf-C2H2 PF00096.21 KFX94398.1 - 2.4e-08 33.8 15.9 2.7e-05 24.2 1.1 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX94398.1 - 9.4e-07 28.7 21.3 9.2e-05 22.5 1.5 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger Zn_clus PF00172.13 KFX94398.1 - 2.3e-05 24.2 9.5 2.3e-05 24.2 6.6 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_jaz PF12171.3 KFX94398.1 - 0.00033 20.7 5.2 0.011 15.8 0.6 2.9 1 1 1 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KFX94398.1 - 0.02 15.1 3.2 0.02 15.1 2.2 4.1 5 1 0 5 5 5 0 Zinc-finger double domain zf-met PF12874.2 KFX94398.1 - 4 7.7 14.5 1.5 9.1 0.5 3.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Abhydrolase_6 PF12697.2 KFX94403.1 - 1.6e-18 67.4 0.4 2.2e-18 67.0 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX94403.1 - 3.9e-08 33.1 0.0 5.3e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family zf-U11-48K PF05253.7 KFX94407.1 - 0.04 13.6 0.0 0.076 12.7 0.0 1.5 1 0 0 1 1 1 0 U11-48K-like CHHC zinc finger DUF2873 PF11395.3 KFX94407.1 - 0.11 12.0 2.2 0.56 9.8 1.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2873) Adeno_E3_CR2 PF02439.10 KFX94407.1 - 2 8.0 5.9 0.35 10.4 0.8 2.3 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 PMP1_2 PF08114.6 KFX94407.1 - 4.5 6.8 7.9 0.7 9.4 0.6 2.9 2 0 0 2 2 2 0 ATPase proteolipid family NAD_binding_10 PF13460.1 KFX94408.1 - 8.8e-11 42.1 1.1 5.6e-10 39.5 0.8 2.1 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX94408.1 - 1.1e-10 41.3 0.0 1.6e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFX94408.1 - 0.0001 21.1 0.0 0.00016 20.4 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KFX94408.1 - 0.00014 21.2 0.1 0.00021 20.5 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family UDPG_MGDP_dh_N PF03721.9 KFX94408.1 - 0.0028 17.0 0.1 0.011 15.0 0.1 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Saccharop_dh PF03435.13 KFX94409.1 - 5.5e-19 68.3 0.2 8.1e-19 67.8 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Lipase_GDSL PF00657.17 KFX94410.1 - 1.3e-09 38.2 3.4 6.3e-09 35.9 2.4 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KFX94410.1 - 5e-09 36.5 0.6 6.6e-09 36.1 0.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family IDO PF01231.13 KFX94411.1 - 5.8e-16 57.9 0.0 6.8e-13 47.8 0.0 2.3 2 0 0 2 2 2 2 Indoleamine 2,3-dioxygenase Cyt-b5 PF00173.23 KFX94411.1 - 8.1e-13 47.9 0.0 2.9e-12 46.2 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_1 PF00667.15 KFX94411.1 - 1.7e-12 47.2 0.0 3.4e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KFX94411.1 - 2.9e-09 37.4 0.0 6.1e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Zn_clus PF00172.13 KFX94412.1 - 8.2e-07 28.8 15.3 8.2e-07 28.8 10.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DBP PF12361.3 KFX94412.1 - 0.021 14.3 2.9 0.036 13.6 1.9 1.3 1 1 0 1 1 1 0 Duffy-antigen binding protein VPS28 PF03997.7 KFX94412.1 - 0.42 10.1 2.4 0.78 9.3 1.6 1.3 1 0 0 1 1 1 0 VPS28 protein DUF4551 PF15087.1 KFX94412.1 - 1 7.6 6.6 1.5 7.1 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) zf-C2H2 PF00096.21 KFX94412.1 - 6.7 7.2 11.2 0.15 12.4 2.0 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type adh_short PF00106.20 KFX94413.1 - 2e-20 73.3 0.0 3e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase APH PF01636.18 KFX94413.1 - 1.1e-08 35.1 0.0 2.6e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family KR PF08659.5 KFX94413.1 - 6.8e-08 32.3 0.1 1.2e-07 31.5 0.0 1.4 2 0 0 2 2 2 1 KR domain Choline_kinase PF01633.15 KFX94413.1 - 7.1e-06 25.7 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Epimerase PF01370.16 KFX94413.1 - 0.00037 20.0 0.0 0.00057 19.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFX94413.1 - 0.00084 18.1 0.1 0.0015 17.2 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Pkinase PF00069.20 KFX94413.1 - 0.0035 16.5 0.0 0.32 10.0 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain F-box PF00646.28 KFX94415.1 - 0.0059 16.2 0.5 0.016 14.8 0.3 1.8 1 0 0 1 1 1 1 F-box domain ArfGap PF01412.13 KFX94417.1 - 5.2e-32 110.0 0.0 8.9e-32 109.3 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RRM_1 PF00076.17 KFX94418.1 - 5.5e-30 102.8 0.0 4.2e-14 51.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX94418.1 - 9.3e-24 83.2 0.0 1.2e-12 47.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX94418.1 - 9.7e-10 38.1 0.0 0.0019 18.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 KFX94418.1 - 0.19 10.1 1.5 0.29 9.5 1.1 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) FAD_binding_1 PF00667.15 KFX94419.1 - 2e-37 128.7 0.0 3.2e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KFX94419.1 - 7.8e-28 97.2 0.0 1.2e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KFX94419.1 - 5.3e-08 33.3 0.0 1.3e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain BaxI_1 PF12811.2 KFX94420.1 - 0.074 12.1 0.4 0.076 12.1 0.2 1.0 1 0 0 1 1 1 0 Bax inhibitor 1 like Pyridox_oxidase PF01243.15 KFX94422.1 - 1.1e-14 54.1 0.1 7.2e-14 51.5 0.0 2.2 3 0 0 3 3 3 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 KFX94422.1 - 0.0056 16.5 0.0 0.39 10.5 0.0 2.2 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Nitroreductase PF00881.19 KFX94423.1 - 4.9e-16 58.9 0.0 5.9e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family PsbY PF06298.6 KFX94423.1 - 0.41 10.2 1.9 0.92 9.0 1.3 1.5 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) ABC_tran PF00005.22 KFX94424.1 - 8e-17 61.8 0.1 2.8e-16 60.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 KFX94424.1 - 0.0034 16.6 0.0 0.0057 15.9 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 KFX94424.1 - 0.0052 15.4 0.1 0.0052 15.4 0.0 1.4 2 0 0 2 2 2 1 Predicted ATPase of the ABC class SbcCD_C PF13558.1 KFX94424.1 - 0.012 15.5 3.5 0.099 12.5 1.2 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 KFX94424.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain PBP_sp32 PF07222.7 KFX94424.1 - 0.25 10.4 5.0 0.34 10.0 3.5 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF2335 PF10097.4 KFX94424.1 - 0.75 9.4 11.1 3.1 7.4 7.7 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2335) FAD_binding_1 PF00667.15 KFX94425.1 - 1.6e-55 187.9 0.0 7.1e-35 120.4 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain NAD_binding_1 PF00175.16 KFX94425.1 - 8.7e-06 26.2 0.0 1.6e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain CAF1 PF04857.15 KFX94431.1 - 7.1e-48 163.2 0.3 8.8e-48 162.9 0.2 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.15 KFX94431.1 - 0.0018 17.7 0.1 0.0054 16.2 0.1 1.8 2 0 0 2 2 2 1 3'-5' exonuclease OmpH PF03938.9 KFX94432.1 - 0.009 15.9 0.9 0.014 15.3 0.6 1.3 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DUF572 PF04502.8 KFX94432.1 - 0.51 9.5 10.4 0.042 13.0 4.1 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) Pex26 PF07163.7 KFX94432.1 - 2 7.2 7.4 0.6 8.9 1.0 2.2 2 0 0 2 2 2 0 Pex26 protein APG6 PF04111.7 KFX94432.1 - 8 5.4 7.4 12 4.8 5.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 PHF5 PF03660.9 KFX94433.1 - 8.7e-34 115.8 6.0 1.3e-33 115.2 4.1 1.3 1 0 0 1 1 1 1 PHF5-like protein E1-E2_ATPase PF00122.15 KFX94434.1 - 9.2e-21 73.9 0.1 1.5e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KFX94434.1 - 2.9e-20 73.2 0.1 7.4e-20 71.9 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFX94434.1 - 1.2e-14 55.3 0.2 1.2e-13 51.9 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFX94434.1 - 1.1e-11 44.5 0.0 2.7e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFX94434.1 - 0.00062 19.4 0.1 0.008 15.7 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFX94434.1 - 0.018 15.2 0.1 0.055 13.6 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase APH PF01636.18 KFX94435.1 - 2.1e-13 50.5 0.1 3.2e-13 49.9 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX94435.1 - 0.014 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF3224 PF11528.3 KFX94436.1 - 9.1e-09 34.9 3.3 2e-08 33.8 2.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3224) DUF1902 PF08972.6 KFX94459.1 - 0.0049 16.4 0.0 0.0076 15.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1902) Abhydrolase_6 PF12697.2 KFX94461.1 - 9.3e-28 97.6 0.0 1.1e-27 97.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX94461.1 - 2.2e-14 53.5 0.1 4.4e-12 46.0 0.0 2.2 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX94461.1 - 4.5e-12 45.9 0.0 9.3e-12 44.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFX94461.1 - 0.00018 21.2 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DUF1057 PF06342.7 KFX94461.1 - 0.00057 18.7 0.0 0.00074 18.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.8 KFX94461.1 - 0.0068 16.0 0.0 0.0097 15.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Ndr PF03096.9 KFX94461.1 - 0.029 12.8 0.0 0.12 10.7 0.0 1.9 3 0 0 3 3 3 0 Ndr family FAD_binding_4 PF01565.18 KFX94463.1 - 7.7e-19 67.5 2.5 1.7e-18 66.4 1.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFX94463.1 - 3.7e-11 42.7 0.0 9e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like DSPc PF00782.15 KFX94464.1 - 4.4e-21 74.8 0.0 1e-20 73.6 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFX94464.1 - 0.0034 16.7 0.0 0.0046 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase BacA PF02673.13 KFX94464.1 - 0.097 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacitracin resistance protein BacA AAA PF00004.24 KFX94466.1 - 5.5e-21 75.1 0.9 2.6e-20 72.9 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFX94466.1 - 0.00027 21.0 0.5 0.0027 17.7 0.4 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFX94466.1 - 0.00032 20.8 0.3 0.022 14.8 0.0 3.1 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 KFX94466.1 - 0.00067 19.3 0.0 0.0016 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KFX94466.1 - 0.0026 18.5 0.0 0.018 15.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFX94466.1 - 0.0046 16.8 0.1 0.014 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFX94466.1 - 0.0091 16.3 0.0 0.041 14.1 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 KFX94466.1 - 0.0099 15.7 0.0 0.083 12.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFX94466.1 - 0.011 15.5 0.1 0.026 14.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_2 PF07724.9 KFX94466.1 - 0.011 15.6 0.0 0.05 13.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 KFX94466.1 - 0.021 15.0 0.4 0.47 10.6 0.0 2.9 3 0 0 3 3 3 0 RNA helicase RuvB_N PF05496.7 KFX94466.1 - 0.027 13.5 0.0 0.052 12.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus RP-C PF03428.8 KFX94466.1 - 0.031 13.7 0.0 0.085 12.3 0.0 1.7 1 0 0 1 1 1 0 Replication protein C N-terminal domain IstB_IS21 PF01695.12 KFX94466.1 - 0.075 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Stirrup PF09061.1 KFX94466.1 - 0.082 12.8 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Stirrup Acetyltransf_1 PF00583.19 KFX94467.1 - 7e-09 35.6 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFX94467.1 - 0.0001 22.3 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX94467.1 - 0.0001 22.3 0.1 0.00015 21.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFX94467.1 - 0.039 13.8 0.0 0.055 13.4 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain ADH_zinc_N PF00107.21 KFX94468.1 - 6.2e-13 48.4 0.0 1.3e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX94468.1 - 8.7e-06 25.4 0.0 7.1e-05 22.5 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFX94468.1 - 7.9e-05 23.5 0.0 0.00021 22.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glyco_hyd_65N_2 PF14498.1 KFX94469.1 - 1.6e-49 168.7 0.1 2.9e-49 167.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Dynamin_N PF00350.18 KFX94469.1 - 8.4e-19 67.9 0.0 1.7e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KFX94469.1 - 9.7e-10 37.6 0.4 4.8e-07 28.8 0.0 2.6 2 0 0 2 2 2 2 Dynamin central region DUF608 PF04685.8 KFX94469.1 - 0.00026 19.8 0.0 0.00045 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF608 MMR_HSR1 PF01926.18 KFX94469.1 - 0.00087 19.2 0.0 0.0045 16.9 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 KFX94469.1 - 0.00092 19.0 1.7 0.0019 18.0 0.0 2.5 3 0 0 3 3 3 1 Dynamin GTPase effector domain FeoB_N PF02421.13 KFX94469.1 - 0.031 13.5 0.0 7 5.9 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Miro PF08477.8 KFX94469.1 - 0.075 13.5 0.0 0.19 12.2 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein MFS_1 PF07690.11 KFX94470.1 - 2.5e-35 121.8 37.7 1.8e-29 102.6 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX94470.1 - 3.6e-12 45.5 6.7 3.6e-12 45.5 4.6 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter PUCC PF03209.10 KFX94470.1 - 0.31 9.6 21.6 0.31 9.6 3.7 3.2 2 1 1 3 3 3 0 PUCC protein MatE PF01554.13 KFX94471.1 - 1e-49 168.2 23.6 6.6e-28 97.3 2.6 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 KFX94471.1 - 7.2e-09 35.5 4.2 7.2e-09 35.5 2.9 4.5 3 2 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Arginase PF00491.16 KFX94472.1 - 1.1e-14 54.3 0.0 1.3e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Arginase family Choline_sulf_C PF12411.3 KFX94475.1 - 0.068 13.0 0.1 0.093 12.5 0.0 1.2 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal Mito_fiss_reg PF05308.6 KFX94479.1 - 7.8 5.7 14.1 7.8 5.7 9.7 1.0 1 0 0 1 1 1 0 Mitochondrial fission regulator TGT PF01702.13 KFX94487.1 - 1.3e-79 266.9 0.0 2.9e-74 249.3 0.0 2.1 1 1 0 2 2 2 2 Queuine tRNA-ribosyltransferase HNH_2 PF13391.1 KFX94489.1 - 4.9e-10 39.0 0.0 9.2e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Beta-lactamase PF00144.19 KFX94490.1 - 3.3e-39 134.8 0.1 4.3e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Fungal_trans_2 PF11951.3 KFX94491.1 - 1.2e-09 37.2 1.0 2e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX94491.1 - 2.3e-07 30.5 10.1 4e-07 29.8 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KFX94492.1 - 7.1e-48 163.2 0.0 9.9e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 IBN_N PF03810.14 KFX94493.1 - 1.9e-08 34.0 0.0 1.7e-07 31.0 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KFX94493.1 - 0.0066 16.3 0.0 0.075 12.9 0.0 2.9 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.17 KFX94493.1 - 0.096 12.8 1.5 44 4.5 0.0 4.5 4 0 0 4 4 4 0 HEAT repeat HORMA PF02301.13 KFX94494.1 - 1.8e-22 79.8 0.0 2.3e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 HORMA domain Chromo PF00385.19 KFX94497.1 - 7.3e-18 64.0 4.5 1e-08 34.6 0.5 2.3 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain IGPD PF00475.13 KFX94506.1 - 1.3e-59 200.2 0.2 2e-59 199.5 0.1 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Rep_fac_C PF08542.6 KFX94508.1 - 2.1e-20 72.5 0.1 4.9e-20 71.2 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KFX94508.1 - 5.1e-12 45.7 0.0 4.4e-10 39.4 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KFX94508.1 - 3.6e-11 43.3 0.0 6.7e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KFX94508.1 - 6.9e-07 29.2 0.0 1.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFX94508.1 - 1.1e-05 25.5 0.1 0.0028 17.7 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFX94508.1 - 1.5e-05 25.1 0.1 0.00038 20.5 0.0 2.4 1 1 2 3 3 3 1 AAA ATPase domain AAA_10 PF12846.2 KFX94508.1 - 4.3e-05 23.1 0.0 0.0086 15.5 0.0 2.2 1 1 1 2 2 2 1 AAA-like domain Viral_helicase1 PF01443.13 KFX94508.1 - 8e-05 22.2 0.0 0.00014 21.4 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.7 KFX94508.1 - 9.3e-05 21.5 0.0 0.00022 20.3 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 KFX94508.1 - 0.00014 20.6 0.0 0.0087 14.7 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 KFX94508.1 - 0.00033 20.2 0.0 0.00064 19.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KFX94508.1 - 0.0022 17.6 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 KFX94508.1 - 0.0023 17.1 0.1 0.032 13.3 0.0 2.5 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 KFX94508.1 - 0.0026 17.2 0.0 0.005 16.3 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family DEAD PF00270.24 KFX94508.1 - 0.0026 17.2 0.1 0.11 11.9 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase NTPase_1 PF03266.10 KFX94508.1 - 0.0059 16.3 0.1 0.051 13.2 0.0 2.3 1 1 0 2 2 2 1 NTPase ArgK PF03308.11 KFX94508.1 - 0.01 14.6 0.0 0.02 13.6 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_31 PF13614.1 KFX94508.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KFX94508.1 - 0.013 15.0 0.1 0.029 13.9 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFX94508.1 - 0.018 14.4 0.1 0.078 12.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain DNA_pol3_delta PF06144.8 KFX94508.1 - 0.03 13.8 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit KTI12 PF08433.5 KFX94508.1 - 0.032 13.4 0.0 0.054 12.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NB-ARC PF00931.17 KFX94508.1 - 0.085 11.6 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 KFX94508.1 - 0.088 12.9 0.0 0.35 11.0 0.0 2.0 1 1 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KFX94508.1 - 0.09 13.0 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Asp PF00026.18 KFX94509.1 - 2.6e-72 243.7 2.6 3.4e-72 243.3 1.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFX94509.1 - 7.3e-11 42.2 0.0 3.7e-10 39.9 0.0 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KFX94509.1 - 4.9e-06 26.1 0.0 1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KFX94509.1 - 0.018 15.4 0.2 12 6.4 0.0 3.5 2 1 0 2 2 2 0 Aspartyl protease HTH_23 PF13384.1 KFX94513.1 - 0.00019 20.9 0.2 0.00037 20.0 0.2 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.1 KFX94513.1 - 0.00041 21.0 6.4 0.25 12.1 0.4 2.6 1 1 1 2 2 2 2 Homeodomain-like domain HTH_38 PF13936.1 KFX94513.1 - 0.04 13.4 1.2 0.12 11.9 0.8 1.9 1 1 0 1 1 1 0 Helix-turn-helix domain Helicase_C PF00271.26 KFX94514.1 - 5.2e-18 64.6 0.3 7.6e-18 64.1 0.2 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFX94515.1 - 2.8e-26 92.0 0.2 3.9e-15 55.7 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 KFX94515.1 - 0.00012 21.9 2.0 0.00012 21.9 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KFX94515.1 - 0.00015 20.6 0.2 0.00053 18.8 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain ParA PF10609.4 KFX94515.1 - 0.14 12.0 0.8 0.25 11.2 0.1 1.7 2 0 0 2 2 2 0 ParA/MinD ATPase like DDHD PF02862.12 KFX94515.1 - 4.4 7.0 7.0 26 4.5 0.0 2.2 2 0 0 2 2 2 0 DDHD domain ADH_N PF08240.7 KFX94516.1 - 6.5e-28 96.6 2.1 1.3e-27 95.7 1.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ATP-synt_G PF04718.10 KFX94516.1 - 2.4e-27 95.6 0.5 7.3e-27 94.0 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit ADH_zinc_N PF00107.21 KFX94516.1 - 4.6e-15 55.3 0.0 8.9e-15 54.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 KFX94516.1 - 0.094 12.7 0.2 0.46 10.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 KFX94517.1 - 1e-46 158.3 0.0 4e-46 156.3 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFX94517.1 - 1.3e-06 27.9 0.0 3.1e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ELYS PF13934.1 KFX94520.1 - 3.4e-62 210.1 0.1 4.1e-62 209.8 0.1 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.14 KFX94521.1 - 7.5e-75 250.9 13.1 2.9e-74 248.9 9.1 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KFX94521.1 - 3e-26 91.7 0.0 1.6e-25 89.4 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KFX94521.1 - 4.9e-11 43.1 11.3 2.6e-05 24.3 0.2 3.9 3 2 1 4 4 4 2 AAA domain AAA_23 PF13476.1 KFX94521.1 - 6.8e-09 36.3 9.9 6.8e-09 36.3 6.9 6.6 2 2 2 4 4 1 1 AAA domain AAA_29 PF13555.1 KFX94521.1 - 0.00022 20.7 0.0 0.00044 19.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Tropomyosin_1 PF12718.2 KFX94521.1 - 0.00028 20.7 13.1 0.00028 20.7 9.1 7.6 4 3 4 8 8 7 2 Tropomyosin like IncA PF04156.9 KFX94521.1 - 0.0013 18.3 7.9 0.0013 18.3 5.5 8.1 2 2 7 9 9 8 4 IncA protein Reo_sigmaC PF04582.7 KFX94521.1 - 0.0014 17.9 5.0 0.0014 17.9 3.5 4.8 2 2 2 4 4 4 2 Reovirus sigma C capsid protein Lebercilin PF15619.1 KFX94521.1 - 0.005 16.2 13.1 0.005 16.2 9.1 7.2 3 2 1 6 6 4 1 Ciliary protein causing Leber congenital amaurosis disease AAA_13 PF13166.1 KFX94521.1 - 0.006 15.1 102.8 0.019 13.4 23.3 5.8 3 2 2 6 6 6 3 AAA domain DivIC PF04977.10 KFX94521.1 - 0.0077 15.6 0.6 0.0077 15.6 0.4 10.5 8 5 5 13 13 13 2 Septum formation initiator Y_phosphatase PF00102.22 KFX94522.1 - 2.1e-46 158.1 0.0 3e-46 157.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 KFX94522.1 - 0.0017 17.9 0.0 0.0062 16.1 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 KFX94522.1 - 0.032 14.2 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF2697 PF10906.3 KFX94523.1 - 2.2e-05 24.3 0.0 5.8e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2697) DUF1192 PF06698.6 KFX94526.1 - 0.0028 17.4 0.5 3.2 7.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1192) FGF-BP1 PF06473.7 KFX94527.1 - 0.02 14.4 2.1 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) RRM_1 PF00076.17 KFX94528.1 - 5.2e-44 147.7 0.0 8.2e-17 60.6 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX94528.1 - 1.5e-24 85.7 0.0 2e-09 37.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX94528.1 - 1.1e-20 73.2 0.0 2.7e-08 33.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFX94528.1 - 5.4e-06 26.2 0.0 0.0001 22.1 0.0 2.5 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 KFX94528.1 - 8.9e-05 22.1 0.0 0.0088 15.7 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif 4HBT PF03061.17 KFX94532.1 - 1.9e-12 47.1 0.0 4e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily NTR2 PF15458.1 KFX94535.1 - 1.4e-66 224.3 22.1 1.8e-66 223.9 15.3 1.1 1 0 0 1 1 1 1 Nineteen complex-related protein 2 DUF3385 PF11865.3 KFX94536.1 - 0.079 12.8 0.6 2.4 8.0 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3385) zf-rbx1 PF12678.2 KFX94538.1 - 1.4e-09 37.9 0.4 2.5e-09 37.0 0.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KFX94538.1 - 1.6e-09 37.4 3.5 1.3e-08 34.5 0.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KFX94538.1 - 2.3e-06 27.1 0.8 4e-06 26.3 0.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX94538.1 - 9.9e-06 25.1 2.1 2.3e-05 24.0 1.4 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFX94538.1 - 2.5e-05 23.8 3.3 7.1e-05 22.3 2.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFX94538.1 - 0.00012 22.0 2.2 0.00012 22.0 1.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF2921 PF11145.3 KFX94538.1 - 0.014 13.1 0.3 0.02 12.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) zf-Apc11 PF12861.2 KFX94538.1 - 0.015 15.0 1.1 0.039 13.7 0.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KFX94538.1 - 0.18 11.5 5.3 0.034 13.8 0.8 2.0 2 1 0 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 KFX94538.1 - 0.45 10.5 2.9 1.8 8.5 2.0 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain HSBP1 PF06825.7 KFX94539.1 - 8.9e-14 50.8 1.1 1.3e-13 50.3 0.7 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 DUF2379 PF09543.5 KFX94539.1 - 0.064 13.2 0.1 0.076 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) DUF2884 PF11101.3 KFX94539.1 - 0.1 11.9 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Thioredoxin PF00085.15 KFX94540.1 - 1.3e-58 195.1 0.0 2.2e-29 101.2 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 KFX94540.1 - 7.3e-21 74.6 4.5 1.6e-20 73.4 2.7 1.9 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 KFX94540.1 - 1.5e-19 70.2 0.7 1.8e-10 40.9 0.0 3.7 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KFX94540.1 - 8.7e-17 60.9 0.0 4.4e-07 29.8 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 KFX94540.1 - 4e-13 49.2 0.3 0.00016 21.6 0.0 3.6 3 1 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.16 KFX94540.1 - 5.5e-09 35.7 0.1 0.0037 16.9 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 KFX94540.1 - 4.2e-07 29.6 0.6 0.026 14.0 0.0 2.8 3 0 0 3 3 3 2 Redoxin Thioredoxin_3 PF13192.1 KFX94540.1 - 5.1e-05 23.0 0.1 0.13 12.0 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin domain Thioredoxin_9 PF14595.1 KFX94540.1 - 0.00017 21.1 0.2 0.17 11.4 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin TraF PF13728.1 KFX94540.1 - 0.00027 20.4 0.0 0.01 15.3 0.0 2.4 2 0 0 2 2 2 1 F plasmid transfer operon protein HyaE PF07449.6 KFX94540.1 - 0.0028 17.5 0.0 0.13 12.1 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_4 PF13462.1 KFX94540.1 - 0.0056 16.6 3.6 7.4 6.5 0.1 3.8 3 1 1 4 4 4 1 Thioredoxin DDE_Tnp_1_2 PF13586.1 KFX94540.1 - 0.012 15.7 0.0 0.28 11.4 0.0 2.5 2 0 0 2 2 2 0 Transposase DDE domain Helicase_C_4 PF13871.1 KFX94540.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Helicase_C-like DUF953 PF06110.6 KFX94540.1 - 0.15 11.4 1.5 0.66 9.4 0.1 2.5 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF953) DSBA PF01323.15 KFX94540.1 - 0.99 8.9 5.3 6.3 6.2 0.1 3.4 3 1 1 4 4 4 0 DSBA-like thioredoxin domain MKT1_C PF12246.3 KFX94541.1 - 1.7e-55 187.6 0.0 2.7e-55 187.0 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 KFX94541.1 - 5.1e-26 90.8 0.1 1.6e-25 89.2 0.1 1.9 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 KFX94541.1 - 0.016 15.2 0.0 0.044 13.8 0.0 1.8 1 0 0 1 1 1 0 XPG I-region XPG_N PF00752.12 KFX94541.1 - 0.078 13.2 0.0 0.43 10.8 0.0 2.3 1 0 0 1 1 1 0 XPG N-terminal domain DUF1882 PF08966.6 KFX94542.1 - 0.044 13.7 0.0 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1882) Pfg27 PF09216.5 KFX94542.1 - 0.059 12.9 0.7 0.15 11.6 0.6 1.5 2 0 0 2 2 2 0 Pfg27 DUF1632 PF07857.7 KFX94542.1 - 0.33 10.1 0.0 0.33 10.1 0.0 1.5 2 0 0 2 2 2 0 CEO family (DUF1632) TruB_N PF01509.13 KFX94543.1 - 6.1e-48 162.7 0.2 1.8e-47 161.2 0.3 1.7 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) Sec2p PF06428.6 KFX94544.1 - 8.6e-08 31.9 11.7 8.7e-08 31.9 5.3 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Jnk-SapK_ap_N PF09744.4 KFX94544.1 - 0.00019 21.4 10.2 0.053 13.5 3.8 2.1 2 0 0 2 2 2 2 JNK_SAPK-associated protein-1 DUF444 PF04285.7 KFX94544.1 - 0.029 13.0 0.8 0.043 12.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF444) Herpes_U30 PF04523.8 KFX94544.1 - 0.039 11.4 2.8 0.63 7.4 0.4 2.0 2 0 0 2 2 2 0 Herpes virus tegument protein U30 zf-RING_3 PF14369.1 KFX94544.1 - 0.072 13.0 0.2 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 zinc-finger CpXC PF14353.1 KFX94544.1 - 0.23 11.4 1.1 0.79 9.6 0.0 2.1 2 0 0 2 2 2 0 CpXC protein SlyX PF04102.7 KFX94544.1 - 0.34 11.2 16.5 0.37 11.1 0.9 3.7 2 2 2 4 4 4 0 SlyX DUF883 PF05957.8 KFX94544.1 - 0.57 10.6 8.4 0.2 12.0 0.5 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) TPR_MLP1_2 PF07926.7 KFX94544.1 - 0.96 9.1 12.7 0.51 10.0 0.8 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 KFX94544.1 - 1.7 6.3 3.1 2.3 5.9 2.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Caudo_TAP PF02413.12 KFX94544.1 - 3.2 7.9 11.2 0.36 10.9 1.4 2.6 1 1 0 2 2 2 0 Caudovirales tail fibre assembly protein Myosin_tail_1 PF01576.14 KFX94544.1 - 3.4 5.2 20.3 2.7 5.5 0.7 2.2 2 0 0 2 2 2 0 Myosin tail OmpH PF03938.9 KFX94544.1 - 4.1 7.3 11.7 5.6 6.8 0.5 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF3584 PF12128.3 KFX94544.1 - 4.2 4.5 14.8 20 2.3 10.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) IncA PF04156.9 KFX94544.1 - 4.6 6.7 18.4 3.5 7.1 1.0 2.1 1 1 1 2 2 2 0 IncA protein COG2 PF06148.6 KFX94544.1 - 4.9 7.0 6.9 13 5.6 0.1 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3373 PF11853.3 KFX94544.1 - 6.3 5.2 5.1 9.5 4.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3373) AAA_13 PF13166.1 KFX94544.1 - 9.2 4.5 6.1 27 3.0 0.2 1.8 1 1 0 1 1 1 0 AAA domain Ribosomal_L32e PF01655.13 KFX94545.1 - 1.9e-29 101.9 0.2 3.5e-29 101.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L32 DnaJ PF00226.26 KFX94545.1 - 4e-23 80.9 2.7 1e-22 79.6 1.9 1.7 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KFX94545.1 - 2.7e-21 75.2 1.5 1.5e-19 69.6 0.0 3.3 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KFX94545.1 - 5.7e-14 51.9 18.7 1.1e-13 51.0 13.0 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KFX94545.1 - 0.0046 16.6 7.3 0.26 10.9 0.9 2.5 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 KFX94545.1 - 4.5 7.6 9.3 0.32 11.3 2.8 1.9 2 0 0 2 2 2 0 Cytochrome c3 DUF1356 PF07092.7 KFX94545.1 - 7.2 5.7 6.5 11 5.1 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) tRNA-synt_1c PF00749.16 KFX94546.1 - 1.4e-89 299.8 0.0 1.8e-89 299.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Synthase_beta PF11421.3 KFX94546.1 - 0.2 12.3 6.1 0.6 10.8 4.2 1.8 1 0 0 1 1 1 0 ATP synthase F1 beta subunit JAB PF01398.16 KFX94547.1 - 1.5e-29 102.0 0.1 5.4e-29 100.2 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KFX94547.1 - 6.6e-08 32.0 0.0 1.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MAP65_ASE1 PF03999.7 KFX94548.1 - 7.3e-76 256.0 9.4 1.1e-75 255.4 6.5 1.3 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) BLOC1_2 PF10046.4 KFX94548.1 - 3 8.0 8.2 1.3 9.2 0.1 3.8 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2205 PF10224.4 KFX94548.1 - 3.9 7.1 7.1 8.5 6.0 0.1 3.5 3 0 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) EF-hand_4 PF12763.2 KFX94549.1 - 0.00083 19.0 0.1 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 KFX94549.1 - 0.0095 15.1 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KFX94549.1 - 0.083 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.1 KFX94549.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 EF-hand domain pair Ferritin_2 PF13668.1 KFX94552.1 - 4.9e-11 42.7 2.5 2.4e-06 27.5 0.3 2.1 1 1 1 2 2 2 2 Ferritin-like domain WSC PF01822.14 KFX94555.1 - 7.9e-18 64.1 8.8 1.3e-17 63.5 6.1 1.3 1 0 0 1 1 1 1 WSC domain DUF3439 PF11921.3 KFX94555.1 - 0.93 9.2 10.4 0.61 9.8 5.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Ank_2 PF12796.2 KFX94557.1 - 1.2e-46 156.9 5.4 9.4e-18 64.3 0.1 4.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFX94557.1 - 1.8e-42 141.0 8.5 2.2e-07 30.3 0.0 7.5 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 KFX94557.1 - 1.8e-35 120.7 7.8 3.7e-10 40.0 0.1 6.6 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX94557.1 - 3.9e-34 113.2 4.4 8.4e-05 22.4 0.0 8.4 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 KFX94557.1 - 1.3e-27 95.2 11.3 6.6e-07 29.3 0.1 6.5 3 2 2 6 6 6 6 Ankyrin repeats (many copies) TMF_TATA_bd PF12325.3 KFX94557.1 - 0.08 12.6 3.2 1.6 8.4 1.0 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding COesterase PF00135.23 KFX94558.1 - 4.2e-93 312.8 0.0 5.1e-93 312.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX94558.1 - 1.9e-05 24.3 0.0 7e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFX94558.1 - 0.0062 15.7 0.1 0.0095 15.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Methyltransf_2 PF00891.13 KFX94561.1 - 9.9e-27 93.6 0.0 1.6e-26 93.0 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Sel1 PF08238.7 KFX94562.1 - 1.1e-41 140.2 32.3 2.6e-05 24.7 0.3 12.5 12 1 1 13 13 13 9 Sel1 repeat TPR_7 PF13176.1 KFX94562.1 - 0.00091 18.8 4.8 59 3.8 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Snapin_Pallidin PF14712.1 KFX94562.1 - 0.13 12.6 0.1 0.32 11.3 0.1 1.6 1 0 0 1 1 1 0 Snapin/Pallidin TPR_17 PF13431.1 KFX94562.1 - 0.52 10.6 6.9 7.4 7.0 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.27 KFX94563.1 - 2.9e-15 55.4 0.4 0.0079 16.0 0.0 5.7 5 1 0 5 5 5 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KFX94563.1 - 0.00011 20.6 0.0 0.00017 20.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain NIF PF03031.13 KFX94564.1 - 4e-51 172.8 0.2 6.8e-51 172.0 0.1 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sec61_beta PF03911.11 KFX94565.1 - 8.6e-20 70.2 2.3 8.6e-20 70.2 1.6 1.9 2 0 0 2 2 2 1 Sec61beta family Clr2 PF10383.4 KFX94566.1 - 1.5e-06 28.2 0.0 3.8e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 Fungal_trans_2 PF11951.3 KFX94568.1 - 0.012 14.2 0.0 0.017 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain FBD PF08387.5 KFX94568.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 FBD Aconitase PF00330.15 KFX94570.1 - 1.1e-157 525.2 0.0 2.7e-157 523.9 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Fn_bind PF02986.9 KFX94571.1 - 0.019 14.4 0.5 0.13 11.8 0.2 2.6 2 0 0 2 2 2 0 Fibronectin binding repeat Epimerase PF01370.16 KFX94576.1 - 2e-11 43.8 0.0 2.7e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX94576.1 - 8.1e-11 42.2 0.1 1.1e-10 41.7 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFX94576.1 - 4e-09 35.5 0.0 5.6e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Dynamin_M PF01031.15 KFX94577.1 - 6.3e-114 379.7 0.0 1.6e-113 378.4 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KFX94577.1 - 4.4e-56 189.3 0.6 1.3e-55 187.7 0.0 2.2 2 0 0 2 2 2 1 Dynamin family GED PF02212.13 KFX94577.1 - 2.3e-31 107.5 2.5 2.3e-31 107.5 1.7 2.5 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KFX94577.1 - 0.00053 19.9 0.2 0.0051 16.7 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFX94577.1 - 0.015 15.8 0.0 0.048 14.1 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein zf-CCHC_4 PF14392.1 KFX94577.1 - 0.12 12.0 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 Zinc knuckle SH3_9 PF14604.1 KFX94578.1 - 5.5e-31 105.9 2.9 8e-16 57.3 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KFX94578.1 - 2.2e-26 91.0 5.4 5.7e-14 51.2 0.3 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KFX94578.1 - 6.9e-16 57.4 0.2 3.8e-07 29.4 0.0 2.7 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 KFX94578.1 - 8.2e-11 41.8 0.0 1.5e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Zw10 PF06248.8 KFX94579.1 - 6.4e-05 21.3 0.3 0.00048 18.4 0.2 2.1 1 1 0 1 1 1 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 KFX94579.1 - 0.00061 19.0 0.0 0.0013 17.9 0.0 1.5 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal LRR_4 PF12799.2 KFX94580.1 - 0.00016 21.2 5.3 0.21 11.2 0.1 5.2 6 0 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KFX94580.1 - 0.0023 17.8 10.8 0.7 10.1 0.0 7.5 9 0 0 9 9 9 1 Leucine Rich repeat LRR_8 PF13855.1 KFX94580.1 - 0.021 14.5 8.8 4.5 7.0 0.3 5.0 3 2 1 5 5 5 0 Leucine rich repeat SNF2_N PF00176.18 KFX94581.1 - 3e-58 196.9 0.0 5.1e-58 196.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFX94581.1 - 1.7e-13 50.2 0.0 6.1e-13 48.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 KFX94581.1 - 9.5e-06 25.1 10.9 9.5e-06 25.1 7.6 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KFX94581.1 - 1.5e-05 24.8 0.0 3.5e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFX94581.1 - 0.00065 19.2 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.1 KFX94581.1 - 0.0057 16.6 10.5 0.0057 16.6 7.3 2.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.1 KFX94581.1 - 0.037 12.7 0.0 0.11 11.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 DUF3881 PF12997.2 KFX94581.1 - 0.099 11.6 0.1 0.19 10.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) zf-RING_2 PF13639.1 KFX94581.1 - 3.8 7.4 25.0 0.039 13.7 9.5 2.5 2 0 0 2 2 2 0 Ring finger domain DUF3613 PF12266.3 KFX94582.1 - 0.088 12.3 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3613) MGC-24 PF05283.6 KFX94583.1 - 0.21 11.3 4.8 0.24 11.1 3.3 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Pkinase PF00069.20 KFX94584.1 - 6.2e-08 32.1 0.0 1e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KFX94584.1 - 0.00013 21.8 0.1 0.00033 20.4 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KFX94584.1 - 0.0018 17.3 0.0 0.0032 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX94584.1 - 0.11 11.4 0.0 0.23 10.3 0.0 1.5 1 0 0 1 1 1 0 Kinase-like HD PF01966.17 KFX94587.1 - 3e-08 33.6 0.3 3.8e-08 33.3 0.2 1.2 1 0 0 1 1 1 1 HD domain Methyltransf_23 PF13489.1 KFX94588.1 - 1.1e-11 44.6 0.1 2.1e-11 43.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX94588.1 - 2e-08 34.7 0.0 2.6e-07 31.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX94588.1 - 4.3e-05 23.9 0.0 8.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX94588.1 - 4.9e-05 22.9 0.0 0.00053 19.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX94588.1 - 0.00011 22.5 0.0 0.0011 19.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX94588.1 - 0.00036 20.8 0.0 0.0019 18.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KFX94588.1 - 0.0022 17.0 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_PK PF05891.7 KFX94588.1 - 0.0072 15.6 0.2 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.13 KFX94588.1 - 0.012 14.7 0.1 0.029 13.5 0.0 1.6 1 1 0 1 1 1 0 O-methyltransferase CheR PF01739.13 KFX94588.1 - 0.028 13.7 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_26 PF13659.1 KFX94588.1 - 0.069 13.1 0.0 0.19 11.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KFX94588.1 - 0.1 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF914 PF06027.7 KFX94590.1 - 1.1e-106 356.4 21.5 1.4e-106 356.1 14.9 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 KFX94590.1 - 0.00027 20.9 12.3 0.00027 20.9 8.5 2.4 2 1 0 2 2 2 1 EamA-like transporter family Tim17 PF02466.14 KFX94590.1 - 0.041 13.9 0.3 0.1 12.6 0.2 1.6 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Condensation PF00668.15 KFX94593.1 - 1.4e-27 96.3 0.0 1.9e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 KFX94593.1 - 6.4e-12 45.5 0.1 1.7e-11 44.2 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site RTC4 PF14474.1 KFX94595.1 - 7e-26 90.6 0.0 1.2e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain Glyco_hydro_43 PF04616.9 KFX94595.1 - 1.6e-11 43.8 2.2 3.1e-11 42.8 1.5 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Cu-oxidase_3 PF07732.10 KFX94597.1 - 1.5e-42 144.0 3.9 1.7e-42 143.8 0.4 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFX94597.1 - 1.4e-30 105.6 12.2 7e-30 103.3 2.1 3.9 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KFX94597.1 - 1.2e-29 103.2 6.3 1.3e-29 103.1 0.0 3.6 5 1 1 6 6 6 1 Multicopper oxidase p450 PF00067.17 KFX94598.1 - 3.5e-50 170.8 0.0 8.2e-50 169.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 KFX94599.1 - 1.7e-72 243.9 0.1 3.7e-72 242.8 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KFX94599.1 - 2.9e-48 164.8 0.0 6.2e-48 163.7 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Thioesterase PF00975.15 KFX94599.1 - 2.2e-35 122.9 0.0 8.5e-35 121.0 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain Ketoacyl-synt_C PF02801.17 KFX94599.1 - 2.6e-35 120.8 2.3 5.2e-35 119.8 0.7 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KFX94599.1 - 1.6e-19 69.9 2.5 1.9e-09 37.6 0.1 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 KFX94599.1 - 8.4e-15 54.6 0.0 1.6e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 KFX94599.1 - 3.1e-06 27.2 3.0 0.00016 21.6 0.0 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX94599.1 - 3.9e-05 23.4 0.0 0.14 11.9 0.0 2.8 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 KFX94599.1 - 0.00017 20.6 0.1 0.00038 19.5 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain CcmH PF03918.9 KFX94599.1 - 0.09 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein adh_short_C2 PF13561.1 KFX94600.1 - 1.7e-26 93.4 0.0 2.5e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFX94600.1 - 3.4e-26 92.1 0.0 5.7e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX94600.1 - 1.1e-10 41.4 0.0 2.4e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFX94600.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 KFX94600.1 - 0.19 10.7 0.0 0.55 9.2 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FAD_binding_4 PF01565.18 KFX94602.1 - 6.2e-27 93.7 1.7 9.4e-27 93.1 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFX94602.1 - 4.5e-14 52.0 0.0 9.1e-14 51.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Choline_kinase PF01633.15 KFX94606.1 - 0.15 11.6 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Cupin_1 PF00190.17 KFX94607.1 - 5.3e-12 45.3 0.1 7.6e-12 44.8 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 KFX94607.1 - 0.00039 19.8 0.1 0.00069 19.0 0.0 1.4 1 0 0 1 1 1 1 Cupin domain MARVEL PF01284.18 KFX94608.1 - 0.00093 19.0 14.7 0.026 14.3 6.2 2.1 1 1 1 2 2 2 2 Membrane-associating domain DUF4418 PF14387.1 KFX94608.1 - 0.035 13.8 0.5 0.035 13.8 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4418) Tetraspannin PF00335.15 KFX94608.1 - 6.2 6.0 11.9 2.9e+02 0.5 8.2 2.1 1 1 0 1 1 1 0 Tetraspanin family Thymidylat_synt PF00303.14 KFX94610.1 - 8.1e-100 333.2 0.0 1e-99 332.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase CDP-OH_P_transf PF01066.16 KFX94617.1 - 2.8e-17 62.8 4.2 2.8e-17 62.8 2.9 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase SRP19 PF01922.12 KFX94618.1 - 1.2e-24 86.6 0.0 2.3e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 SRP19 protein CBFB_NFYA PF02045.10 KFX94620.1 - 1.7e-29 102.0 4.3 1.7e-29 102.0 3.0 2.4 3 0 0 3 3 3 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B ORC6 PF05460.8 KFX94620.1 - 0.19 10.7 3.1 0.35 9.9 2.2 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) BRO1 PF03097.13 KFX94626.1 - 3.5e-133 444.0 2.0 3.5e-133 444.0 1.4 2.5 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KFX94626.1 - 1.6e-91 306.3 11.9 1.6e-91 306.3 8.2 2.5 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV Lon_C PF05362.8 KFX94626.1 - 7.9e-62 208.2 0.0 1.9e-61 206.9 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KFX94626.1 - 1.9e-36 125.6 0.1 1.9e-36 125.6 0.1 2.4 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KFX94626.1 - 3.8e-22 78.9 0.0 1.2e-21 77.3 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFX94626.1 - 1.3e-06 28.1 0.0 3.6e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 KFX94626.1 - 9.3e-06 25.1 0.0 2.5e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.1 KFX94626.1 - 3.1e-05 24.1 0.1 0.00055 20.0 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 KFX94626.1 - 7.2e-05 21.6 0.0 0.00014 20.6 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_17 PF13207.1 KFX94626.1 - 0.0001 23.1 0.1 0.00077 20.2 0.0 2.7 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 KFX94626.1 - 0.00047 19.2 0.0 0.0027 16.8 0.0 2.2 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KFX94626.1 - 0.00051 20.0 3.4 0.0019 18.2 0.0 3.5 4 0 0 4 4 3 1 AAA ATPase domain AAA_14 PF13173.1 KFX94626.1 - 0.0083 16.0 0.0 0.025 14.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFX94626.1 - 0.023 15.0 3.6 0.059 13.6 0.0 3.4 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 KFX94626.1 - 0.092 12.9 0.0 0.33 11.1 0.0 2.0 1 0 0 1 1 1 0 RNA helicase GRP PF07172.6 KFX94626.1 - 0.45 11.0 8.2 1.5 9.3 5.7 1.9 1 0 0 1 1 1 0 Glycine rich protein family Pkinase PF00069.20 KFX94627.1 - 1e-11 44.5 0.0 4.1e-10 39.2 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX94627.1 - 3.7e-10 39.3 0.0 3e-09 36.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase HMG_box PF00505.14 KFX94639.1 - 1.5e-13 50.7 0.1 2.9e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFX94639.1 - 3.8e-10 39.9 0.1 7.3e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.25 KFX94639.1 - 8.4e-10 38.6 0.0 1.6e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFX94639.1 - 4.2e-08 32.9 0.0 9.6e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFX94640.1 - 3.4e-11 43.1 0.1 4.1e-11 42.8 0.0 1.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFX94640.1 - 4e-06 26.5 0.0 4.6e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) APH PF01636.18 KFX94642.1 - 4.8e-11 42.8 0.0 2.7e-10 40.4 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KFX94642.1 - 0.15 11.0 0.0 5.2 5.9 0.0 2.3 2 0 0 2 2 2 0 Fructosamine kinase DUF3435 PF11917.3 KFX94644.1 - 3.3e-110 368.6 0.0 4.7e-110 368.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) HIT PF01230.18 KFX94645.1 - 1.9e-19 69.9 0.1 3.8e-19 69.0 0.0 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 KFX94645.1 - 1.2e-06 28.7 0.0 2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KFX94645.1 - 0.0022 17.6 0.0 0.0061 16.2 0.0 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 APH PF01636.18 KFX94646.1 - 4.8e-10 39.5 0.0 6.5e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KFX94646.1 - 5.8e-07 28.9 0.1 8.8e-07 28.3 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 KFX94646.1 - 3.1e-06 26.9 0.2 9.8e-06 25.2 0.2 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 KFX94646.1 - 0.00045 19.2 0.0 0.00075 18.5 0.0 1.4 1 0 0 1 1 1 1 Fructosamine kinase DUF1679 PF07914.6 KFX94646.1 - 0.001 17.7 0.1 0.0015 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) TraQ PF09679.5 KFX94647.1 - 0.045 13.6 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) Dynamin_N PF00350.18 KFX94648.1 - 3.9e-20 72.3 0.0 9.3e-19 67.8 0.0 2.7 2 1 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KFX94648.1 - 4.8e-14 51.8 1.9 4.7e-12 45.2 0.1 2.3 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 KFX94648.1 - 9.5e-07 28.6 0.5 4.3e-06 26.5 0.4 2.2 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KFX94648.1 - 9.6e-05 22.3 0.0 1.3 8.9 0.0 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase F-box PF00646.28 KFX94648.1 - 0.0057 16.2 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain AAA_29 PF13555.1 KFX94648.1 - 0.12 11.8 0.0 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ApbA_C PF08546.6 KFX94656.1 - 1.2e-32 112.5 0.0 1.8e-32 112.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KFX94656.1 - 2.1e-19 69.4 0.0 5.1e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pkinase PF00069.20 KFX94657.1 - 7.2e-58 195.7 0.0 1.3e-57 194.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX94657.1 - 1.3e-31 109.6 0.0 2.1e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX94657.1 - 2.4e-14 52.9 0.0 6.2e-12 45.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Lant_dehyd_C PF04738.8 KFX94657.1 - 0.28 9.3 2.5 1.5 6.9 1.9 1.8 2 0 0 2 2 2 0 Lantibiotic dehydratase, C terminus AAA PF00004.24 KFX94660.1 - 1.9e-13 50.7 0.0 1.1e-12 48.2 0.0 2.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 KFX94660.1 - 2.8e-12 46.4 0.0 5.4e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 KFX94660.1 - 7.8e-12 44.6 0.0 1.4e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein DNA_pol3_delta2 PF13177.1 KFX94660.1 - 2.9e-11 43.3 0.0 1.1e-07 31.7 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase III, delta subunit AAA_22 PF13401.1 KFX94660.1 - 3.3e-06 27.2 0.0 0.00096 19.3 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KFX94660.1 - 0.00011 21.9 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFX94660.1 - 0.00013 21.6 0.0 0.00032 20.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 KFX94660.1 - 0.00022 20.3 0.0 0.00052 19.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KFX94660.1 - 0.00027 20.9 0.2 0.0072 16.3 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.16 KFX94660.1 - 0.005 16.0 0.0 0.37 9.9 0.0 2.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KFX94660.1 - 0.0071 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KFX94660.1 - 0.0095 15.5 0.6 0.031 13.8 0.4 2.0 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 KFX94660.1 - 0.016 14.7 0.0 0.036 13.5 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase III, delta subunit FtsK_SpoIIIE PF01580.13 KFX94660.1 - 0.016 14.6 0.3 0.27 10.6 0.0 2.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family TMP_2 PF06791.8 KFX94660.1 - 0.046 13.3 0.1 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 Prophage tail length tape measure protein DUF815 PF05673.8 KFX94660.1 - 0.051 12.4 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.9 KFX94660.1 - 0.052 13.2 0.1 0.75 9.5 0.1 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KFX94660.1 - 0.067 12.7 0.0 0.69 9.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KFX94660.1 - 0.068 13.9 0.0 0.21 12.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KFX94660.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2417 PF10329.4 KFX94661.1 - 8.3e-86 287.1 1.0 1.1e-85 286.6 0.7 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 KFX94661.1 - 2.7e-07 30.6 0.2 5.7e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family TMEM51 PF15345.1 KFX94661.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Abhydrolase_6 PF12697.2 KFX94662.1 - 2.5e-21 76.6 0.0 5.2e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX94662.1 - 4.2e-10 39.5 0.0 6.5e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX94662.1 - 0.00011 21.8 0.0 0.0082 15.7 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold UPF0261 PF06792.6 KFX94662.1 - 0.024 13.1 0.0 0.039 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) Hydrolase_4 PF12146.3 KFX94662.1 - 0.024 14.4 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase PGAP1 PF07819.8 KFX94662.1 - 0.025 14.1 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 KFX94662.1 - 0.053 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.15 KFX94662.1 - 0.095 12.9 0.0 0.51 10.5 0.0 2.0 1 1 0 1 1 1 0 Thioesterase domain Esterase PF00756.15 KFX94662.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.16 KFX94662.1 - 0.18 10.9 0.0 2.9 7.0 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Sec20 PF03908.8 KFX94663.1 - 8e-14 51.1 2.4 1.1e-13 50.6 0.0 2.4 3 1 0 3 3 3 1 Sec20 Exonuc_VII_L PF02601.10 KFX94663.1 - 3.4 6.7 8.8 1.2 8.2 3.3 1.8 1 1 1 2 2 2 0 Exonuclease VII, large subunit MRP_L53 PF10780.4 KFX94664.1 - 1.2e-19 69.9 1.0 2.5e-19 68.9 0.7 1.6 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 RTC_insert PF05189.8 KFX94665.1 - 5.5e-31 106.6 0.1 9.8e-31 105.8 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.16 KFX94665.1 - 2e-30 105.3 0.1 2.8e-30 104.7 0.1 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RicinB_lectin_2 PF14200.1 KFX94666.1 - 6.7e-30 103.5 4.3 6.3e-16 58.6 0.1 2.9 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 KFX94666.1 - 2.9e-05 24.0 0.4 7.9e-05 22.6 0.1 1.9 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain Glyco_hydro_61 PF03443.9 KFX94667.1 - 1.1e-74 250.9 0.3 1.2e-74 250.7 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MafB19-deam PF14437.1 KFX94667.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 MafB19-like deaminase UDPGT PF00201.13 KFX94668.1 - 0.00013 20.6 0.0 0.0002 20.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PWWP PF00855.12 KFX94669.1 - 4.8e-13 49.1 0.3 4.8e-13 49.1 0.2 3.5 2 2 0 2 2 2 1 PWWP domain Sec63 PF02889.11 KFX94670.1 - 2.5e-134 447.4 0.0 4.9e-85 285.5 0.0 2.4 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.24 KFX94670.1 - 5.8e-18 64.9 0.1 1.9e-17 63.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KFX94670.1 - 0.0001 22.1 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pkinase PF00069.20 KFX94680.1 - 0.023 13.8 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Zn_clus PF00172.13 KFX94682.1 - 3.7e-07 29.9 15.8 5.2e-07 29.4 10.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX94683.1 - 7.4e-21 74.1 3.0 7.4e-21 74.1 2.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain TSA PF03249.8 KFX94683.1 - 0.03 12.8 0.2 0.045 12.2 0.2 1.1 1 0 0 1 1 1 0 Type specific antigen Mpv17_PMP22 PF04117.7 KFX94684.1 - 3.5e-24 84.2 0.3 3.5e-24 84.2 0.2 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family PGK PF00162.14 KFX94685.1 - 2.9e-150 500.1 1.4 3.3e-150 499.9 1.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PrpR_N PF06506.6 KFX94685.1 - 0.17 11.3 0.5 0.48 9.8 0.1 1.9 2 0 0 2 2 2 0 Propionate catabolism activator DSS1_SEM1 PF05160.8 KFX94686.1 - 6.1e-24 83.5 14.7 8.1e-24 83.1 10.2 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family S_layer_N PF05123.7 KFX94686.1 - 0.077 12.6 1.9 0.089 12.4 1.3 1.0 1 0 0 1 1 1 0 S-layer like family, N-terminal region FAD_binding_4 PF01565.18 KFX94692.1 - 2e-22 79.1 1.0 3.4e-22 78.3 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain SKG6 PF08693.5 KFX94693.1 - 2e-06 26.9 0.6 3.8e-06 26.0 0.4 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain WSC PF01822.14 KFX94693.1 - 1.6e-05 24.7 3.1 1.6e-05 24.7 2.2 1.7 2 0 0 2 2 2 1 WSC domain Podoplanin PF05808.6 KFX94693.1 - 0.0003 20.3 0.1 0.00044 19.8 0.1 1.2 1 0 0 1 1 1 1 Podoplanin Alpha_GJ PF03229.8 KFX94693.1 - 0.003 17.9 3.3 0.0043 17.3 2.3 1.2 1 0 0 1 1 1 1 Alphavirus glycoprotein J Shisa PF13908.1 KFX94693.1 - 0.003 17.7 0.2 0.05 13.7 0.1 2.1 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF4448 PF14610.1 KFX94693.1 - 0.01 15.3 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) KR PF08659.5 KFX94705.1 - 7.1e-60 201.7 0.1 7.1e-60 201.7 0.1 1.7 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KFX94705.1 - 8.9e-48 162.3 1.7 4.1e-47 160.1 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.21 KFX94705.1 - 1.8e-17 63.1 0.9 3.9e-17 62.0 0.6 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX94705.1 - 9e-10 39.5 1.3 1.3e-08 35.7 0.9 3.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX94705.1 - 5.8e-09 35.6 0.9 2e-08 33.9 0.7 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 KFX94705.1 - 0.026 14.7 0.0 0.065 13.5 0.0 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site Microtub_assoc PF07989.6 KFX94736.1 - 2.6e-27 94.4 3.4 2.6e-27 94.4 2.4 11.5 7 4 7 15 15 15 2 Microtubule associated PACT_coil_coil PF10495.4 KFX94736.1 - 2.5e-19 68.9 0.0 9.1e-19 67.1 0.0 2.1 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein CENP-F_leu_zip PF10473.4 KFX94736.1 - 8.1e-05 22.4 15.0 8.1e-05 22.4 10.4 11.1 3 3 4 9 9 9 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 KFX94736.1 - 0.0039 16.9 5.1 0.0039 16.9 3.5 11.9 1 1 10 12 12 12 2 TPR/MLP1/MLP2-like protein Filament PF00038.16 KFX94736.1 - 8.2 5.7 175.7 0.18 11.2 15.6 6.6 1 1 5 6 6 6 0 Intermediate filament protein SGT1 PF07093.6 KFX94737.1 - 1.9e-138 462.4 39.4 6.5e-137 457.4 27.3 2.0 1 1 0 1 1 1 1 SGT1 protein Sec62 PF03839.11 KFX94737.1 - 0.42 9.9 1.7 0.75 9.1 1.1 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 THUMP PF02926.12 KFX94739.1 - 2.2e-08 34.1 0.2 6.2e-07 29.3 0.0 2.5 2 1 0 2 2 2 1 THUMP domain TPP_enzyme_N PF02776.13 KFX94740.1 - 1e-33 116.2 0.0 1.6e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KFX94740.1 - 2.6e-24 85.5 0.0 5.5e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KFX94740.1 - 8.4e-14 51.4 0.0 2.4e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 KFX94740.1 - 0.026 13.2 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component OCC1 PF15506.1 KFX94740.1 - 0.17 11.8 1.8 14 5.6 0.0 3.2 3 0 0 3 3 3 0 OCC1 family Pkinase PF00069.20 KFX94741.1 - 1.7e-62 210.9 0.0 6.9e-62 208.9 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX94741.1 - 1.4e-45 155.4 0.0 2.6e-45 154.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX94741.1 - 4.9e-10 38.8 0.0 3.2e-07 29.6 0.0 2.9 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 KFX94741.1 - 0.016 14.2 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sugar_tr PF00083.19 KFX94743.1 - 4.1e-73 246.5 23.8 4.7e-73 246.2 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX94743.1 - 1.1e-31 109.8 31.4 3.7e-26 91.6 13.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFX94743.1 - 7.4e-07 27.7 7.1 1.2e-05 23.7 3.6 2.3 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF3419 PF11899.3 KFX94751.1 - 4.1e-54 183.7 0.1 6.1e-54 183.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) DUF4448 PF14610.1 KFX94751.1 - 6e-34 117.1 0.0 1.4e-33 115.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) Methyltransf_23 PF13489.1 KFX94751.1 - 1.9e-11 43.9 0.0 5.2e-11 42.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX94751.1 - 2.4e-09 37.5 0.0 1.1e-08 35.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX94751.1 - 2.6e-08 34.4 0.0 1e-07 32.5 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX94751.1 - 1e-07 31.6 0.0 3.7e-07 29.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX94751.1 - 1.9e-07 31.1 0.0 6.7e-06 26.1 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX94751.1 - 1.7e-05 24.0 0.0 0.014 14.4 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KFX94751.1 - 4e-05 24.0 0.0 0.0072 16.7 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX94751.1 - 0.00011 22.4 0.0 0.00027 21.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KFX94751.1 - 0.00092 18.9 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KFX94751.1 - 0.001 18.6 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_28 PF02636.12 KFX94751.1 - 0.013 14.9 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF2391 PF09622.5 KFX94751.1 - 0.12 11.5 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) Velvet PF11754.3 KFX94787.1 - 8.8e-56 188.7 0.2 2.3e-55 187.3 0.2 1.7 1 1 0 1 1 1 1 Velvet factor tRNA-synt_2c PF01411.14 KFX94789.1 - 5.6e-08 31.5 0.0 6e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) Peptidase_M43 PF05572.8 KFX94790.1 - 3.2e-17 62.5 0.4 5.5e-17 61.7 0.3 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 KFX94790.1 - 3.2e-06 27.1 2.9 5.2e-06 26.5 2.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 KFX94790.1 - 4.9e-05 23.4 0.7 7e-05 22.9 0.5 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KFX94790.1 - 0.00014 22.3 1.9 0.00031 21.2 1.2 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 KFX94790.1 - 0.0011 18.6 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 KFX94790.1 - 0.0022 16.9 0.2 0.0029 16.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase M66 Peptidase_M57 PF12388.3 KFX94790.1 - 0.0052 16.1 0.3 0.0052 16.1 0.2 1.8 2 0 0 2 2 2 1 Dual-action HEIGH metallo-peptidase Reprolysin_4 PF13583.1 KFX94790.1 - 0.015 14.8 2.0 0.025 14.0 1.3 1.6 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M54 PF07998.6 KFX94790.1 - 0.15 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 CYSTM PF12734.2 KFX94791.1 - 3.4e-11 43.0 17.6 3.4e-11 43.0 12.2 5.3 2 1 3 5 5 5 1 Cysteine-rich TM module stress tolerance Pex14_N PF04695.8 KFX94791.1 - 5.3 7.1 8.5 15 5.6 5.9 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2046 PF09755.4 KFX94792.1 - 0.033 13.0 0.8 0.033 13.0 0.6 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) ketoacyl-synt PF00109.21 KFX94796.1 - 3.8e-18 65.8 0.0 7.5e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KFX94796.1 - 1.6e-10 40.8 0.3 5.1e-10 39.2 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 KFX94796.1 - 9e-05 22.4 0.1 0.00025 20.9 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Bromodomain PF00439.20 KFX94810.1 - 3.8e-16 58.7 0.2 1.3e-15 57.0 0.1 2.0 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 KFX94810.1 - 1.4e-08 34.3 0.0 3.6e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated Glucosamine_iso PF01182.15 KFX94813.1 - 6.2e-61 205.6 0.0 7.2e-61 205.3 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase SET PF00856.23 KFX94814.1 - 9.5e-05 22.7 0.0 0.021 15.1 0.0 2.7 3 1 0 3 3 3 2 SET domain zf-MYND PF01753.13 KFX94814.1 - 0.0011 18.8 7.3 0.0011 18.8 5.1 2.3 2 0 0 2 2 2 1 MYND finger MA3 PF02847.12 KFX94816.1 - 5.3e-26 90.5 0.0 2.6e-25 88.3 0.0 2.2 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.14 KFX94816.1 - 7.4e-26 90.8 0.8 1.8e-25 89.6 0.3 1.8 2 0 0 2 2 2 1 MIF4G domain CENP-B_dimeris PF09026.5 KFX94816.1 - 4.2 7.6 13.7 0.3 11.3 4.0 2.7 2 1 0 2 2 2 0 Centromere protein B dimerisation domain DPM2 PF07297.7 KFX94817.1 - 8.1e-33 112.5 2.1 1.5e-32 111.6 1.5 1.5 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 KFX94817.1 - 0.005 16.4 1.5 0.012 15.2 1.1 1.5 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 KFX94817.1 - 0.034 14.0 1.1 0.12 12.3 0.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF4083 PF13314.1 KFX94817.1 - 0.35 10.7 0.2 0.72 9.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) PROL5-SMR PF15621.1 KFX94817.1 - 2.3 8.6 0.0 2.3 8.6 0.0 5.0 6 1 1 7 7 7 0 Proline-rich submaxillary gland androgen-regulated family DUF1295 PF06966.7 KFX94819.1 - 7.5e-36 123.5 6.5 9.6e-36 123.2 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Ribosomal_S18 PF01084.15 KFX94826.1 - 2.4e-13 49.7 0.0 5.4e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 PPR_2 PF13041.1 KFX94827.1 - 1.3e-09 37.8 0.9 2.3 8.2 0.0 6.7 5 1 2 7 7 7 4 PPR repeat family PPR_3 PF13812.1 KFX94827.1 - 2.9e-09 36.4 2.5 0.033 14.4 0.0 7.2 9 0 0 9 9 9 2 Pentatricopeptide repeat domain PPR PF01535.15 KFX94827.1 - 0.00062 19.5 10.8 1 9.5 0.0 6.7 9 0 0 9 9 9 2 PPR repeat Fungal_trans PF04082.13 KFX94832.1 - 1.1e-25 89.9 0.0 2.6e-25 88.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX94832.1 - 1.1e-09 38.0 6.1 2e-09 37.2 4.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bap31 PF05529.7 KFX94833.1 - 1e-64 217.5 4.9 1.2e-64 217.3 3.4 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Filament PF00038.16 KFX94833.1 - 0.0035 16.8 2.6 0.0054 16.2 1.8 1.2 1 0 0 1 1 1 1 Intermediate filament protein She9_MDM33 PF05546.6 KFX94833.1 - 0.0082 15.7 0.5 0.016 14.8 0.4 1.4 1 0 0 1 1 1 1 She9 / Mdm33 family TMF_DNA_bd PF12329.3 KFX94833.1 - 0.011 15.4 5.3 0.014 15.1 3.1 1.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Phage_GP20 PF06810.6 KFX94833.1 - 0.019 14.4 5.6 0.033 13.6 3.9 1.4 1 1 0 1 1 1 0 Phage minor structural protein GP20 DivIC PF04977.10 KFX94833.1 - 0.037 13.5 1.0 0.037 13.5 0.7 2.7 3 0 0 3 3 3 0 Septum formation initiator Lge1 PF11488.3 KFX94833.1 - 0.039 14.1 0.2 0.076 13.2 0.2 1.5 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 IncA PF04156.9 KFX94833.1 - 0.06 12.9 0.4 0.13 11.8 0.2 1.6 1 0 0 1 1 1 0 IncA protein DUF4446 PF14584.1 KFX94833.1 - 0.58 9.9 3.3 0.94 9.3 0.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) PMT PF02366.13 KFX94839.1 - 3.4e-80 268.9 14.3 3.4e-80 268.9 9.9 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KFX94839.1 - 5.2e-39 133.7 0.2 7.1e-39 133.3 0.2 1.2 1 0 0 1 1 1 1 MIR domain Sugar_tr PF00083.19 KFX94840.1 - 1e-102 344.0 19.0 1.2e-102 343.7 13.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX94840.1 - 9.3e-32 110.0 44.7 5.7e-29 100.9 15.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX94840.1 - 3.7e-06 25.6 20.6 0.00073 18.0 2.9 3.0 3 0 0 3 3 3 2 MFS/sugar transport protein DUF791 PF05631.9 KFX94840.1 - 0.002 16.9 1.1 0.0034 16.1 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1_like PF12832.2 KFX94840.1 - 0.0084 15.8 0.1 0.0084 15.8 0.1 2.3 3 0 0 3 3 3 1 MFS_1 like family MFS_3 PF05977.8 KFX94840.1 - 0.17 9.9 4.7 0.45 8.5 0.2 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Chs3p PF12271.3 KFX94841.1 - 5.8e-101 337.3 6.7 6.9e-101 337.0 4.7 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF998 PF06197.8 KFX94841.1 - 0.0034 16.7 16.4 0.0088 15.3 1.6 2.5 1 1 0 2 2 2 2 Protein of unknown function (DUF998) YvrJ PF12841.2 KFX94841.1 - 0.038 13.2 0.0 0.087 12.1 0.0 1.6 1 0 0 1 1 1 0 YvrJ protein family DUF202 PF02656.10 KFX94841.1 - 0.92 9.7 0.0 0.92 9.7 0.0 4.5 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Ssl1 PF04056.9 KFX94842.1 - 3.1e-72 242.2 0.0 3.9e-72 241.8 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 KFX94842.1 - 1.7e-11 44.5 0.0 2.5e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 KFX94842.1 - 0.00083 19.0 0.1 0.032 13.9 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain Inhibitor_I9 PF05922.11 KFX94857.1 - 0.00012 22.5 0.1 0.00013 22.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 ExbD PF02472.11 KFX94857.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.5 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR VHS PF00790.14 KFX94858.1 - 2.3e-05 24.0 0.0 4.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 VHS domain CTD_bind PF04818.8 KFX94858.1 - 0.00047 20.3 0.0 0.0011 19.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.3 KFX94858.1 - 0.016 15.3 1.5 0.056 13.5 1.0 1.9 1 1 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 zf-RING_2 PF13639.1 KFX94858.1 - 0.12 12.2 0.9 0.18 11.6 0.1 1.7 2 0 0 2 2 2 0 Ring finger domain zf-C2H2_4 PF13894.1 KFX94858.1 - 0.86 10.0 4.0 4.3 7.9 0.2 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KFX94858.1 - 1.4 8.6 4.9 10 5.8 1.0 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Pil1 PF13805.1 KFX94859.1 - 7.9e-150 497.4 0.2 9.9e-150 497.1 0.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 KFX94859.1 - 0.029 13.6 2.2 0.094 12.0 1.5 1.8 1 1 0 1 1 1 0 FAM92 protein LSM PF01423.17 KFX94860.1 - 5.8e-06 25.7 0.0 7.7e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain XPG_N PF00752.12 KFX94861.1 - 5.9e-29 100.3 0.0 2.2e-28 98.4 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KFX94861.1 - 2.4e-26 91.6 0.0 6e-26 90.3 0.0 1.7 1 0 0 1 1 1 1 XPG I-region UIM PF02809.15 KFX94861.1 - 0.0078 15.7 0.7 0.0078 15.7 0.5 3.6 4 0 0 4 4 4 1 Ubiquitin interaction motif 5_3_exonuc PF01367.15 KFX94861.1 - 0.0089 16.2 0.0 0.028 14.6 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Lipase_GDSL_2 PF13472.1 KFX94868.1 - 2.9e-09 37.2 1.1 3.3e-09 37.1 0.8 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFX94868.1 - 2.6e-08 34.0 1.0 2.9e-08 33.8 0.7 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_35 PF01301.14 KFX94869.1 - 2.3e-77 260.4 6.3 4e-77 259.7 4.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 KFX94869.1 - 1e-54 184.6 5.1 2e-54 183.7 3.5 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 KFX94869.1 - 2.5e-48 162.9 1.3 5.9e-25 87.7 0.7 3.0 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 KFX94869.1 - 3.6e-24 83.9 0.3 1.7e-23 81.7 0.4 2.0 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Pyr_redox_2 PF07992.9 KFX94870.1 - 3.6e-12 46.5 0.0 9.8e-12 45.1 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX94870.1 - 7e-11 42.3 0.4 3.3e-08 33.7 0.3 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFX94870.1 - 1.1e-06 28.9 0.1 0.02 14.9 0.0 3.1 1 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFX94870.1 - 1.9e-05 23.7 6.4 0.033 13.0 0.1 3.7 2 1 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KFX94870.1 - 2.4e-05 23.4 0.0 0.0012 17.8 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KFX94870.1 - 3.1e-05 23.7 3.3 0.062 13.0 0.0 4.3 5 1 0 5 5 5 2 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KFX94870.1 - 0.029 13.0 0.3 5 5.6 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase CoA_binding_2 PF13380.1 KFX94870.1 - 0.11 12.6 0.2 9.3 6.4 0.0 2.3 2 0 0 2 2 2 0 CoA binding domain MFS_1 PF07690.11 KFX94871.1 - 8e-28 97.1 52.7 1.6e-15 56.6 23.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFX94871.1 - 0.00019 21.1 2.5 0.00019 21.1 1.7 3.0 4 0 0 4 4 4 1 MFS_1 like family Sugar_tr PF00083.19 KFX94871.1 - 0.0038 15.8 8.8 0.0038 15.8 6.1 4.1 1 1 1 3 3 3 1 Sugar (and other) transporter DUF1072 PF06380.6 KFX94871.1 - 1.2 8.8 8.4 4.8 6.9 0.4 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) Fungal_trans PF04082.13 KFX94872.1 - 1e-14 54.0 0.0 1.6e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX94872.1 - 3.5e-07 30.0 8.9 6.3e-07 29.1 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KFX94872.1 - 1 9.5 13.1 1.1 9.4 7.8 1.9 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Cutinase PF01083.17 KFX94873.1 - 9.8e-53 178.5 3.9 1.2e-52 178.2 2.7 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KFX94873.1 - 0.0028 17.1 0.1 0.0043 16.5 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 KFX94873.1 - 0.013 15.2 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) adh_short PF00106.20 KFX94875.1 - 8.1e-18 64.8 2.7 1.1e-17 64.4 1.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX94875.1 - 2e-10 40.6 2.1 3e-10 40.0 1.5 1.2 1 0 0 1 1 1 1 KR domain CD24 PF14984.1 KFX94876.1 - 0.19 11.5 4.3 0.25 11.1 2.7 1.6 1 1 0 1 1 1 0 CD24 protein Sulfatase PF00884.18 KFX94886.1 - 8.3e-39 133.5 0.0 1.1e-38 133.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 KFX94886.1 - 1.7e-21 75.7 0.3 4.2e-21 74.5 0.2 1.7 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 KFX94886.1 - 0.00015 21.2 0.0 0.00015 21.2 0.0 1.8 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KFX94886.1 - 0.031 13.6 0.0 0.069 12.5 0.0 1.5 1 1 0 1 1 1 0 Metalloenzyme superfamily RXT2_N PF08595.6 KFX94891.1 - 0.038 13.8 0.1 0.046 13.5 0.1 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DDRGK PF09756.4 KFX94893.1 - 0.064 12.6 0.2 0.084 12.2 0.1 1.1 1 0 0 1 1 1 0 DDRGK domain DUF2764 PF10962.3 KFX94893.1 - 0.064 12.4 0.4 0.078 12.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2764) Gly_transf_sug PF04488.10 KFX94893.1 - 0.066 13.6 0.0 0.078 13.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase sugar-binding region containing DXD motif zf-H2C2_5 PF13909.1 KFX94895.1 - 5.3 7.4 12.8 1.1 9.5 3.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 KFX94905.1 - 5.5e-11 42.1 11.1 1.3e-05 25.2 0.2 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFX94905.1 - 3.7e-10 39.5 11.5 2e-05 24.6 3.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX94905.1 - 3.8e-07 29.9 9.1 0.0002 21.4 1.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KFX94905.1 - 6.8e-06 26.1 1.5 2e-05 24.6 1.0 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFX94905.1 - 8e-05 22.6 5.1 0.00012 22.0 1.4 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFX94905.1 - 0.00089 19.0 7.1 0.004 16.9 1.1 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KFX94905.1 - 0.046 13.8 1.1 0.046 13.8 0.8 1.8 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 KFX94905.1 - 2.6 7.9 5.9 21 4.9 4.1 2.2 1 1 0 1 1 1 0 BED zinc finger zf-H2C2_5 PF13909.1 KFX94905.1 - 4.6 7.6 7.7 14 6.1 1.9 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain SF3b1 PF08920.5 KFX94906.1 - 7.4e-40 136.3 0.8 7.4e-40 136.3 0.6 2.2 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 KFX94906.1 - 1.5e-14 54.0 2.5 0.011 16.0 0.0 7.4 6 2 1 7 7 7 4 HEAT repeats HEAT_EZ PF13513.1 KFX94906.1 - 4.5e-11 42.8 1.3 0.34 11.4 0.0 7.8 7 2 2 9 9 9 2 HEAT-like repeat HEAT PF02985.17 KFX94906.1 - 9.8e-10 37.6 9.2 1 9.6 0.0 9.4 10 0 0 10 10 10 2 HEAT repeat Vac14_Fab1_bd PF12755.2 KFX94906.1 - 3e-05 24.3 0.4 0.69 10.3 0.0 5.5 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KFX94906.1 - 0.00022 19.7 0.3 0.069 11.4 0.0 3.0 2 1 0 3 3 3 2 Adaptin N terminal region NUC173 PF08161.7 KFX94906.1 - 0.0073 15.6 0.1 5.4 6.3 0.0 3.7 3 0 0 3 3 3 1 NUC173 domain UPF0236 PF06782.6 KFX94906.1 - 0.011 14.1 0.1 0.02 13.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0236) CLASP_N PF12348.3 KFX94906.1 - 0.017 14.4 0.1 0.92 8.8 0.0 3.2 3 0 0 3 3 3 0 CLASP N terminal DUF2945 PF11160.3 KFX94913.1 - 6e-13 48.3 0.6 1.3e-12 47.3 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2945) FAD_binding_3 PF01494.14 KFX94915.1 - 9.2e-19 67.7 0.0 1.7e-18 66.8 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KFX94915.1 - 1.8e-05 24.6 0.0 5e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFX94915.1 - 0.00022 21.5 0.0 0.0008 19.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFX94915.1 - 0.00034 20.5 0.1 0.0015 18.4 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFX94915.1 - 0.00042 19.3 0.5 0.0015 17.5 0.3 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFX94915.1 - 0.00078 18.0 0.1 0.0012 17.4 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 KFX94915.1 - 0.0027 16.6 0.0 0.0048 15.8 0.0 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 KFX94915.1 - 0.01 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KFX94915.1 - 0.023 13.7 1.2 0.062 12.3 0.8 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase SE PF08491.5 KFX94915.1 - 0.048 12.4 0.0 0.086 11.6 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Thi4 PF01946.12 KFX94915.1 - 0.053 12.6 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 KFX94915.1 - 0.054 12.1 0.1 5.7 5.4 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.19 KFX94915.1 - 0.11 11.3 0.0 0.23 10.2 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Peptidase_M24 PF00557.19 KFX94916.1 - 7.2e-44 149.8 0.2 8.7e-44 149.5 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 KFX94916.1 - 2.7e-05 23.9 4.5 7e-05 22.6 3.1 1.8 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 KFX94916.1 - 0.37 10.4 2.9 0.9 9.2 2.0 1.7 1 0 0 1 1 1 0 HIT zinc finger Cornichon PF03311.9 KFX94917.1 - 2.1e-54 183.1 10.9 2.3e-54 182.9 7.5 1.0 1 0 0 1 1 1 1 Cornichon protein WD40 PF00400.27 KFX94918.1 - 1.6e-37 126.0 2.5 7.9e-10 38.2 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KFX94918.1 - 9.2e-05 20.7 0.2 0.056 11.5 0.0 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Glyco_hydro_32N PF00251.15 KFX94928.1 - 1.3e-37 129.8 0.0 3.1e-37 128.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KFX94928.1 - 2.9e-13 49.9 0.1 5e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_43 PF04616.9 KFX94928.1 - 0.11 11.5 0.0 2.2 7.3 0.0 2.6 2 1 0 3 3 3 0 Glycosyl hydrolases family 43 RNA_pol_3_Rpc31 PF11705.3 KFX94930.1 - 1.1e-48 166.2 3.2 1.2e-48 166.0 2.2 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.8 KFX94930.1 - 0.033 14.0 1.4 0.031 14.1 1.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CobT PF06213.7 KFX94930.1 - 0.12 11.4 5.3 0.15 11.1 3.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2457 PF10446.4 KFX94930.1 - 5.1 5.7 13.0 6.8 5.3 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ribosomal_60s PF00428.14 KFX94930.1 - 5.1 7.5 10.1 11 6.5 7.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Fungal_trans PF04082.13 KFX94943.1 - 3.4e-18 65.4 1.0 4.8e-18 64.9 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-RING_UBOX PF13445.1 KFX94943.1 - 0.21 11.3 2.2 0.45 10.2 1.5 1.5 1 0 0 1 1 1 0 RING-type zinc-finger DAO PF01266.19 KFX94949.1 - 4.9e-50 170.4 0.5 1e-49 169.3 0.4 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_4 PF01565.18 KFX94949.1 - 7.7e-20 70.7 0.3 2.4e-18 65.9 0.1 3.0 3 0 0 3 3 3 1 FAD binding domain Cellulase PF00150.13 KFX94949.1 - 5.7e-16 58.5 2.9 1.3e-15 57.3 2.0 1.6 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) BBE PF08031.7 KFX94949.1 - 4.9e-11 42.3 0.0 1.1e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like NAD_binding_8 PF13450.1 KFX94949.1 - 1.3e-05 25.1 0.4 0.0022 18.0 0.1 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Cellulase-like PF12876.2 KFX94949.1 - 0.00029 21.2 0.0 0.00071 19.9 0.0 1.7 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 KFX94949.1 - 0.00095 18.3 0.0 0.003 16.7 0.0 1.7 1 1 0 1 1 1 1 Beta-galactosidase Pyr_redox PF00070.22 KFX94949.1 - 0.0021 18.4 0.0 0.07 13.5 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFX94949.1 - 0.013 14.4 1.3 0.036 12.9 0.9 1.7 1 1 0 1 1 1 0 FAD binding domain Mqo PF06039.10 KFX94949.1 - 0.022 12.9 0.1 0.68 8.0 0.0 2.2 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.9 KFX94949.1 - 0.023 14.6 1.5 2.5 7.9 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 KFX94949.1 - 0.048 12.7 0.0 0.45 9.6 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase FAD_binding_3 PF01494.14 KFX94949.1 - 0.06 12.3 0.1 2.2 7.2 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Glyco_hydro_2_C PF02836.12 KFX94949.1 - 0.065 12.1 0.1 0.21 10.4 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolases family 2, TIM barrel domain T5orf172 PF10544.4 KFX94952.1 - 6e-11 42.6 0.6 1.4e-10 41.4 0.4 1.6 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 KFX94952.1 - 9.2e-11 42.0 2.5 2.1e-10 40.9 1.8 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 DUF2457 PF10446.4 KFX94952.1 - 0.0092 14.7 17.0 0.014 14.1 11.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) SDA1 PF05285.7 KFX94952.1 - 0.03 13.5 11.3 0.045 13.0 7.8 1.2 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 KFX94952.1 - 0.44 8.9 12.5 0.63 8.4 8.7 1.1 1 0 0 1 1 1 0 Daxx Family DARPP-32 PF05395.7 KFX94952.1 - 0.69 10.0 8.9 0.96 9.5 4.1 2.3 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 Nop14 PF04147.7 KFX94952.1 - 1.2 6.9 16.6 1.6 6.5 11.5 1.1 1 0 0 1 1 1 0 Nop14-like family Abhydrolase_6 PF12697.2 KFX94953.1 - 8.5e-10 38.8 0.1 1.5e-09 38.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Amidohydro_4 PF13147.1 KFX94953.1 - 2.2e-09 37.7 0.1 9.3e-09 35.7 0.1 2.1 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KFX94953.1 - 1.5e-08 34.7 0.0 2.6e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KFX94953.1 - 1.2e-06 28.0 0.0 2.2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KFX94953.1 - 0.00036 20.2 0.0 0.00097 18.9 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase NDT80_PhoG PF05224.7 KFX94954.1 - 2.1e-31 109.3 0.0 3.3e-31 108.7 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family KH_1 PF00013.24 KFX94955.1 - 1.3e-38 130.4 13.7 1e-15 57.1 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KFX94955.1 - 7.8e-30 101.9 14.0 3.3e-12 45.7 0.8 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KFX94955.1 - 7.6e-10 38.2 9.1 0.01 15.3 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KFX94955.1 - 1.6e-07 30.8 6.2 0.07 12.7 0.1 3.6 4 0 0 4 4 4 3 KH domain KH_5 PF13184.1 KFX94955.1 - 0.00022 20.9 4.6 0.28 11.0 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 KFX94955.1 - 0.0029 17.0 0.7 0.43 10.0 0.1 3.1 3 0 0 3 3 3 1 dUTPase Ank_2 PF12796.2 KFX94958.1 - 5.7e-50 167.6 13.6 3.2e-20 72.2 2.2 3.6 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFX94958.1 - 3e-47 156.1 20.0 4.4e-09 35.7 0.3 8.4 8 1 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.1 KFX94958.1 - 4.5e-35 119.4 9.4 1.1e-08 35.3 0.0 6.7 1 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX94958.1 - 1e-31 105.8 7.9 5.2e-06 26.2 0.1 8.2 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 KFX94958.1 - 5.7e-22 77.2 12.7 5.4e-06 26.4 0.2 7.1 2 2 4 7 7 7 6 Ankyrin repeats (many copies) DUF1843 PF08898.5 KFX94958.1 - 3.2e-05 23.8 5.8 0.52 10.3 0.0 4.4 4 0 0 4 4 4 2 Domain of unknown function (DUF1843) Ferritin_2 PF13668.1 KFX94961.1 - 7.7e-19 68.0 0.2 1.1e-18 67.5 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain Transketolase_N PF00456.16 KFX94961.1 - 0.017 13.9 0.1 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain DUF848 PF05852.6 KFX94962.1 - 0.02 14.7 0.1 0.025 14.4 0.1 1.2 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DivIC PF04977.10 KFX94962.1 - 0.047 13.1 0.1 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF550 PF04447.7 KFX94962.1 - 0.098 12.2 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF550) DUF904 PF06005.7 KFX94962.1 - 0.16 12.2 0.4 0.16 12.2 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF904) 7TMR-HDED PF07697.6 KFX94963.1 - 0.011 15.5 5.3 0.016 14.9 3.7 1.2 1 0 0 1 1 1 0 7TM-HD extracellular CRT-like PF08627.5 KFX94963.1 - 0.037 13.9 0.2 0.063 13.2 0.1 1.4 1 0 0 1 1 1 0 CRT-like Acetyltransf_3 PF13302.1 KFX94965.1 - 3.1e-13 50.1 0.0 4.3e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX94965.1 - 0.00096 19.1 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family WLM PF08325.5 KFX94966.1 - 1.3e-39 136.0 0.0 1.7e-39 135.6 0.0 1.4 1 1 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 KFX94966.1 - 7.2e-09 34.6 11.1 4.7e-08 31.9 0.6 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others SprT-like PF10263.4 KFX94966.1 - 0.0049 16.5 0.1 0.024 14.2 0.0 2.1 2 0 0 2 2 2 1 SprT-like family Mut7-C PF01927.11 KFX94966.1 - 0.018 15.0 0.2 0.036 14.0 0.2 1.4 1 0 0 1 1 1 0 Mut7-C RNAse domain DUF45 PF01863.12 KFX94966.1 - 0.032 14.0 0.2 0.032 14.0 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function DUF45 HutP PF09021.6 KFX94966.1 - 0.091 12.9 1.0 0.15 12.2 0.7 1.3 1 0 0 1 1 1 0 HutP DZR PF12773.2 KFX94966.1 - 9.9 6.0 12.5 1.4e+02 2.3 8.7 2.3 1 1 0 1 1 1 0 Double zinc ribbon DUF1776 PF08643.5 KFX94967.1 - 4.7e-88 295.1 0.0 6e-88 294.8 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Flavi_M PF01004.14 KFX94967.1 - 0.017 14.5 0.4 0.045 13.1 0.1 1.8 2 0 0 2 2 2 0 Flavivirus envelope glycoprotein M MBOAT PF03062.14 KFX94968.1 - 5e-45 154.0 21.7 5e-45 154.0 15.0 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Actin PF00022.14 KFX94969.1 - 5.3e-137 456.4 0.0 6e-137 456.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KFX94969.1 - 0.029 12.9 0.0 4.9 5.6 0.0 2.7 3 0 0 3 3 3 0 MreB/Mbl protein Sec23_trunk PF04811.10 KFX94978.1 - 3.9e-54 183.5 0.0 3e-53 180.7 0.0 2.2 2 1 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KFX94978.1 - 2.1e-26 91.3 0.0 3.6e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KFX94978.1 - 8.7e-18 64.6 0.0 1.5e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KFX94978.1 - 1.5e-16 59.6 5.2 4.1e-16 58.2 3.6 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KFX94978.1 - 1.9e-08 33.8 0.0 4e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat CPSF100_C PF13299.1 KFX94979.1 - 2.2e-41 141.7 0.3 4.8e-41 140.6 0.0 1.8 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 KFX94979.1 - 7.6e-26 90.5 0.0 2.6e-25 88.7 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.7 KFX94979.1 - 2.2e-05 24.1 0.0 4.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 KFX94979.1 - 0.032 13.8 0.1 0.21 11.2 0.0 2.1 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Bestrophin PF01062.16 KFX94983.1 - 6.1e-50 169.8 0.2 3.7e-48 163.9 0.1 2.1 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel PBP_sp32 PF07222.7 KFX94984.1 - 1.9 7.6 6.6 2.2 7.4 4.6 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Myb_DNA-bind_6 PF13921.1 KFX94986.1 - 3.2e-05 23.9 1.9 3.3e-05 23.9 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Beta-lactamase PF00144.19 KFX94989.1 - 6.5e-44 150.3 0.0 9.5e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase WD40 PF00400.27 KFX94990.1 - 1.5e-57 189.5 12.6 2.9e-12 45.9 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat PD40 PF07676.7 KFX94990.1 - 1.1e-14 53.6 3.7 0.28 10.9 0.0 7.4 7 0 0 7 7 7 4 WD40-like Beta Propeller Repeat eIF2A PF08662.6 KFX94990.1 - 2.5e-09 37.1 0.0 3.8e-05 23.4 0.0 2.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 KFX94990.1 - 5.6e-09 35.1 3.6 4.7 6.6 0.0 7.8 8 0 0 8 8 8 2 Proteasome subunit A N-terminal signature Nbas_N PF15492.1 KFX94990.1 - 1.6e-05 24.1 1.7 1.4 7.9 0.0 5.0 1 1 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 KFX94990.1 - 0.0001 20.6 0.7 0.026 12.6 0.1 3.3 1 1 2 3 3 3 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KFX94990.1 - 0.00081 18.9 0.6 1.2 8.5 0.0 3.0 2 2 0 3 3 3 2 PQQ-like domain DPPIV_N PF00930.16 KFX94990.1 - 0.0017 17.0 0.0 0.54 8.7 0.0 3.9 3 1 0 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Zn_clus PF00172.13 KFX94990.1 - 0.0048 16.7 15.6 0.013 15.3 10.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TruB_C PF09142.6 KFX94990.1 - 0.013 15.1 1.5 74 3.1 0.0 5.1 6 0 0 6 6 6 0 tRNA Pseudouridine synthase II, C terminal Cytochrom_D1 PF02239.11 KFX94990.1 - 0.018 13.3 0.0 0.48 8.6 0.0 2.5 2 1 0 2 2 2 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 KFX94990.1 - 0.023 13.4 0.0 4.5 5.9 0.0 2.4 1 1 1 2 2 2 0 Nup133 N terminal like Gmad1 PF10647.4 KFX94990.1 - 0.041 13.2 0.1 4.8 6.5 0.0 3.0 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain MFS_1 PF07690.11 KFX94992.1 - 3e-42 144.6 54.7 4.3e-42 144.0 36.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFX94992.1 - 9.9e-15 53.7 20.2 1.7e-14 52.9 14.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NACHT PF05729.7 KFX94993.1 - 2.3e-09 37.1 1.8 1.3e-08 34.6 0.6 2.7 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KFX94993.1 - 7.4e-06 26.1 0.1 4.2e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KFX94993.1 - 0.0015 18.0 0.9 0.0098 15.3 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 KFX94993.1 - 0.009 16.0 1.9 0.027 14.4 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 KFX94993.1 - 0.014 15.5 0.0 0.05 13.7 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 KFX94993.1 - 0.016 15.5 0.0 0.093 13.0 0.0 2.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KFX94993.1 - 0.019 15.7 0.0 0.16 12.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 KFX94993.1 - 0.029 13.8 0.0 0.1 12.0 0.0 2.0 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Miro PF08477.8 KFX94993.1 - 0.052 14.0 0.0 2 8.9 0.0 3.3 3 0 0 3 3 3 0 Miro-like protein AAA_29 PF13555.1 KFX94993.1 - 0.062 12.8 0.2 0.18 11.3 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KFX94993.1 - 0.066 13.1 0.0 0.5 10.3 0.0 2.5 3 1 0 3 3 3 0 50S ribosome-binding GTPase zf-C2H2 PF00096.21 KFX94994.1 - 9.4e-12 44.5 12.8 9.8e-06 25.6 0.1 3.1 3 1 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX94994.1 - 1.2e-09 37.8 9.8 9.8e-05 22.4 0.1 2.9 3 1 1 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFX94994.1 - 1.5e-08 34.5 12.9 8.1e-07 29.0 0.5 3.1 3 1 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 KFX94994.1 - 7e-05 22.8 1.7 0.32 11.2 0.3 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFX94994.1 - 7.3e-05 22.7 0.7 0.5 10.5 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KFX94994.1 - 0.00024 21.1 4.5 0.0028 17.8 1.1 2.6 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 KFX94994.1 - 0.0087 15.9 5.0 0.16 11.8 0.0 2.5 2 1 0 2 2 2 1 C2H2-type zinc finger zf-CHY PF05495.7 KFX94994.1 - 0.22 11.6 3.4 0.64 10.2 2.4 1.8 1 1 0 1 1 1 0 CHY zinc finger zf-BED PF02892.10 KFX94994.1 - 0.56 10.0 4.0 4.7 7.0 0.1 2.5 2 1 0 2 2 2 0 BED zinc finger DHC_N1 PF08385.7 KFX95004.1 - 2.5e-188 627.1 6.8 2.5e-188 627.1 4.7 5.0 6 0 0 6 6 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 KFX95004.1 - 2.3e-126 421.6 5.1 2.3e-126 421.6 3.6 4.4 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 KFX95004.1 - 1.8e-100 337.0 0.0 5.9e-100 335.3 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 KFX95004.1 - 1e-78 264.0 0.0 3.2e-78 262.4 0.0 1.9 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 KFX95004.1 - 4.1e-43 146.8 0.2 3.5e-42 143.8 0.1 2.7 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 KFX95004.1 - 6.7e-43 146.5 0.3 2.5e-41 141.4 0.2 2.8 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 KFX95004.1 - 6.1e-37 127.1 6.4 2e-36 125.4 4.5 1.9 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KFX95004.1 - 2.3e-32 111.6 0.9 1.4e-11 44.2 0.0 6.9 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 KFX95004.1 - 1.1e-20 73.9 0.0 6.5e-20 71.3 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 KFX95004.1 - 1e-15 58.0 0.0 0.0096 16.0 0.0 6.1 5 0 0 5 5 4 3 AAA domain AAA PF00004.24 KFX95004.1 - 4.9e-14 52.6 0.0 0.0037 17.4 0.0 5.1 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KFX95004.1 - 4e-10 39.7 2.8 0.13 12.0 0.0 5.7 5 0 0 5 5 4 3 AAA domain AAA_17 PF13207.1 KFX95004.1 - 4.1e-10 40.5 2.4 0.03 15.1 0.0 6.7 6 0 0 6 6 5 2 AAA domain T2SE PF00437.15 KFX95004.1 - 6.8e-09 35.0 0.0 0.044 12.6 0.0 3.9 4 0 0 4 4 4 3 Type II/IV secretion system protein AAA_18 PF13238.1 KFX95004.1 - 1.1e-08 35.4 1.5 0.015 15.6 0.0 5.4 5 0 0 5 5 5 2 AAA domain AAA_19 PF13245.1 KFX95004.1 - 9.9e-07 28.4 0.4 0.89 9.3 0.0 5.0 5 0 0 5 5 4 1 Part of AAA domain AAA_16 PF13191.1 KFX95004.1 - 3.7e-06 27.0 17.1 0.18 11.7 0.1 8.6 9 1 1 10 10 10 2 AAA ATPase domain Mg_chelatase PF01078.16 KFX95004.1 - 8.9e-06 24.9 0.8 0.5 9.4 0.0 4.8 4 0 0 4 4 4 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 KFX95004.1 - 3.5e-05 23.2 0.1 2 7.9 0.0 3.8 3 0 0 3 3 3 2 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KFX95004.1 - 0.00028 20.0 0.0 0.95 8.5 0.0 3.7 3 0 0 3 3 3 2 Zeta toxin FtsK_SpoIIIE PF01580.13 KFX95004.1 - 0.00035 20.1 0.0 5.8 6.3 0.0 4.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family ABC_tran PF00005.22 KFX95004.1 - 0.0011 19.2 4.9 3.6 7.9 0.0 5.1 4 0 0 4 4 3 2 ABC transporter RNA_helicase PF00910.17 KFX95004.1 - 0.0073 16.4 0.1 43 4.3 0.0 4.8 4 0 0 4 4 4 0 RNA helicase MobB PF03205.9 KFX95004.1 - 0.017 14.8 0.6 11 5.6 0.0 3.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KFX95004.1 - 0.017 14.6 0.7 7 6.1 0.1 3.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 KFX95004.1 - 0.018 14.4 2.7 0.4 10.0 0.0 3.9 5 0 0 5 5 5 0 AAA domain MAS20 PF02064.10 KFX95005.1 - 3.4e-21 75.3 0.6 2.5e-20 72.6 0.4 1.8 1 1 0 1 1 1 1 MAS20 protein import receptor DUF533 PF04391.7 KFX95005.1 - 0.017 14.5 0.2 0.023 14.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) DUF1079 PF06435.6 KFX95005.1 - 0.034 14.0 0.2 0.072 13.0 0.1 1.5 1 0 0 1 1 1 0 Repeat of unknown function (DUF1079) AAA_32 PF13654.1 KFX95005.1 - 0.26 9.8 3.1 0.34 9.5 2.2 1.1 1 0 0 1 1 1 0 AAA domain Vps51 PF08700.6 KFX95006.1 - 7.2e-16 57.8 2.9 7.2e-16 57.8 2.0 2.1 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 KFX95006.1 - 0.0085 15.9 3.8 0.0087 15.9 0.1 2.6 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2383 PF09537.5 KFX95006.1 - 0.35 11.1 4.5 6.6 7.0 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Sec5 PF15469.1 KFX95006.1 - 0.49 10.0 7.7 1.9 8.2 0.3 2.9 3 0 0 3 3 3 0 Exocyst complex component Sec5 DUF2443 PF10398.4 KFX95006.1 - 0.52 10.1 4.6 2 8.2 0.2 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2443) IncA PF04156.9 KFX95006.1 - 2.8 7.5 8.7 0.099 12.2 0.2 2.5 2 1 0 2 2 2 0 IncA protein Metallophos PF00149.23 KFX95007.1 - 3.8e-43 147.2 2.0 4.9e-43 146.8 0.9 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase 4HBT_3 PF13622.1 KFX95008.1 - 2.7e-30 105.9 0.8 3.4e-30 105.6 0.6 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Esterase_phd PF10503.4 KFX95009.1 - 3.8e-07 29.5 0.0 0.00014 21.2 0.0 2.4 2 0 0 2 2 2 2 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 KFX95009.1 - 7.8e-06 25.7 0.0 1.7e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KFX95009.1 - 9.3e-06 25.2 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 KFX95009.1 - 0.0022 17.2 0.1 0.0079 15.4 0.1 1.9 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KFX95009.1 - 0.0038 16.7 0.0 0.014 14.8 0.0 1.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 KFX95009.1 - 0.059 11.8 0.0 1.2 7.5 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Whi5 PF08528.6 KFX95012.1 - 1.2e-08 34.3 0.0 1.9e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Whi5 like Asp PF00026.18 KFX95014.1 - 2.2e-65 221.0 6.6 2.6e-65 220.7 4.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KFX95014.1 - 0.00013 22.3 4.8 0.0045 17.4 1.4 3.1 2 1 0 2 2 2 1 Aspartyl protease TAXi_N PF14543.1 KFX95014.1 - 0.00059 19.8 0.0 0.0044 16.9 0.0 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal APH PF01636.18 KFX95015.1 - 4.1e-07 29.9 0.6 3e-06 27.1 0.4 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family WSC PF01822.14 KFX95016.1 - 1.5e-38 130.6 30.4 1.1e-19 70.1 6.0 2.8 2 0 0 2 2 2 2 WSC domain peroxidase PF00141.18 KFX95016.1 - 1.3e-19 70.6 0.1 2.6e-19 69.6 0.1 1.4 1 0 0 1 1 1 1 Peroxidase SET PF00856.23 KFX95017.1 - 1e-11 45.3 0.0 7.3e-11 42.6 0.0 2.0 1 1 0 1 1 1 1 SET domain DUF3632 PF12311.3 KFX95024.1 - 1.2e-34 119.7 0.0 1.4e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) HET PF06985.6 KFX95025.1 - 3.4e-29 101.7 0.2 8.1e-29 100.5 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Yip1 PF04893.12 KFX95027.1 - 0.0099 15.3 4.5 0.013 14.9 3.1 1.2 1 0 0 1 1 1 1 Yip1 domain NnrU PF07298.6 KFX95027.1 - 0.01 15.2 1.1 0.011 15.0 0.7 1.2 1 0 0 1 1 1 0 NnrU protein DUF1212 PF06738.7 KFX95027.1 - 0.12 11.7 1.7 0.17 11.3 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) LMBR1 PF04791.11 KFX95027.1 - 0.3 9.6 2.9 0.37 9.3 2.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Peptidase_S10 PF00450.17 KFX95028.1 - 1.7e-84 284.3 0.2 3.1e-84 283.5 0.1 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase Pkinase PF00069.20 KFX95028.1 - 5.2e-24 84.7 0.0 9.4e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Glycos_transf_1 PF00534.15 KFX95028.1 - 5.3e-17 61.7 0.0 1e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KFX95028.1 - 9.9e-07 28.9 0.0 1e-05 25.7 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Pkinase_Tyr PF07714.12 KFX95028.1 - 0.0002 20.5 0.0 0.089 11.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Glyco_trans_1_2 PF13524.1 KFX95028.1 - 0.0073 16.5 0.0 0.034 14.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 TRAM_LAG1_CLN8 PF03798.11 KFX95029.1 - 1.9e-32 112.4 24.0 2.7e-32 111.9 16.6 1.2 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 KFX95029.1 - 4.9e-24 83.5 0.1 2.1e-23 81.5 0.0 2.1 2 0 0 2 2 2 1 TRAM1-like protein TRAM_LAG1_CLN8 PF03798.11 KFX95030.1 - 3.2e-40 137.8 18.0 3.2e-40 137.8 12.5 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KFX95030.1 - 2.7e-18 65.1 0.1 2.7e-18 65.1 0.1 2.0 2 0 0 2 2 2 1 TRAM1-like protein DUF4512 PF14975.1 KFX95030.1 - 0.087 13.6 0.0 0.68 10.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) UQ_con PF00179.21 KFX95031.1 - 4.3e-42 142.8 0.0 4.8e-42 142.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFX95031.1 - 8.2e-07 28.8 0.0 1.1e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFX95031.1 - 0.014 15.3 0.4 0.014 15.3 0.3 1.4 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 KFX95031.1 - 0.074 12.7 0.0 0.098 12.3 0.0 1.2 1 0 0 1 1 1 0 UEV domain Peptidase_S24 PF00717.18 KFX95032.1 - 1.9e-08 33.8 0.0 2.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Rhodanese PF00581.15 KFX95033.1 - 0.0062 16.8 0.0 0.015 15.6 0.0 1.6 1 1 0 1 1 1 1 Rhodanese-like domain cEGF PF12662.2 KFX95033.1 - 0.17 11.5 4.4 0.1 12.2 0.6 2.5 2 0 0 2 2 2 0 Complement Clr-like EGF-like BTB PF00651.26 KFX95034.1 - 6.9e-08 32.4 0.0 1.7e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Glyco_hydro_11 PF00457.12 KFX95035.1 - 1.3e-79 265.8 19.6 1.7e-79 265.4 13.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.13 KFX95035.1 - 5.6e-09 35.5 16.3 5.6e-09 35.5 11.3 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KFX95035.1 - 0.11 12.5 9.3 0.15 12.1 5.9 1.7 1 1 0 1 1 1 0 Toxin 7 ubiquitin PF00240.18 KFX95036.1 - 0.037 13.4 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family GFO_IDH_MocA PF01408.17 KFX95038.1 - 2.7e-18 66.6 0.0 5.3e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KFX95038.1 - 1.3e-16 60.4 0.2 3.7e-16 58.9 0.1 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 KFX95038.1 - 0.07 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Peptidase_S9 PF00326.16 KFX95040.1 - 3.8e-15 55.7 0.0 5.4e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KFX95040.1 - 1.8e-08 34.2 0.0 1.5e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX95040.1 - 1.9e-08 34.1 0.0 2.4e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KFX95040.1 - 3e-06 26.6 0.0 5.4e-06 25.8 0.0 1.3 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 KFX95040.1 - 0.00032 20.6 0.8 0.006 16.4 0.6 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KFX95040.1 - 0.0029 17.1 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF2048 PF09752.4 KFX95040.1 - 0.0039 16.1 0.0 0.0056 15.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Peptidase_S15 PF02129.13 KFX95040.1 - 0.062 12.7 0.0 0.45 9.8 0.0 1.9 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Sugar_tr PF00083.19 KFX95041.1 - 4.6e-74 249.6 30.9 5.5e-74 249.3 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX95041.1 - 1.7e-16 59.8 29.6 1.7e-16 59.8 20.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CMD PF02627.15 KFX95041.1 - 0.14 12.0 0.0 18 5.2 0.0 2.4 2 0 0 2 2 2 0 Carboxymuconolactone decarboxylase family MFS_2 PF13347.1 KFX95041.1 - 1.1 7.5 32.2 0.49 8.7 7.3 3.0 2 2 1 3 3 3 0 MFS/sugar transport protein DHquinase_I PF01487.10 KFX95043.1 - 3.5e-56 190.3 0.0 5.6e-56 189.7 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase DUF3970 PF13113.1 KFX95043.1 - 0.064 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) Sugar_tr PF00083.19 KFX95044.1 - 3e-128 428.2 37.9 3.4e-128 428.0 26.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX95044.1 - 3.3e-20 72.1 53.7 7.3e-17 61.1 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_43 PF04616.9 KFX95045.1 - 3.1e-62 210.2 1.1 6.9e-62 209.1 0.4 1.8 2 1 0 2 2 2 1 Glycosyl hydrolases family 43 Fungal_trans PF04082.13 KFX95046.1 - 2.3e-18 65.9 0.1 3.9e-18 65.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX95046.1 - 8.3e-09 35.2 10.2 1.5e-08 34.4 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YugN PF08868.5 KFX95046.1 - 0.11 12.0 0.0 2.3 7.8 0.0 2.3 2 0 0 2 2 2 0 YugN-like family Cellulase PF00150.13 KFX95048.1 - 2.4e-08 33.5 0.2 2.8e-07 30.0 0.1 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Nramp PF01566.13 KFX95049.1 - 8.9e-63 212.2 17.7 1.6e-62 211.4 12.3 1.3 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Med17 PF10156.4 KFX95050.1 - 0.0017 16.7 0.8 0.0017 16.7 0.6 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Nop14 PF04147.7 KFX95050.1 - 0.005 14.8 9.9 0.0052 14.7 6.9 1.0 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 KFX95050.1 - 2.9 5.8 10.2 3.5 5.5 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.8 KFX95050.1 - 7.7 5.1 14.3 11 4.6 9.9 1.1 1 0 0 1 1 1 0 Paf1 But2 PF09792.4 KFX95052.1 - 9.7e-56 187.4 2.5 1.6e-55 186.7 1.7 1.4 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain tRNA-synt_1 PF00133.17 KFX95053.1 - 3.2e-216 718.9 0.2 5.6e-216 718.1 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KFX95053.1 - 3.8e-27 94.9 0.0 8.2e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KFX95053.1 - 1.3e-19 70.1 0.1 5.4e-07 28.6 0.0 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) Thioredoxin PF00085.15 KFX95054.1 - 5.4e-20 71.0 0.0 1.5e-19 69.5 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Acetyltransf_4 PF13420.1 KFX95054.1 - 1.1e-09 38.3 0.0 0.00091 19.1 0.0 3.6 3 1 0 3 3 3 2 Acetyltransferase (GNAT) domain Thioredoxin_2 PF13098.1 KFX95054.1 - 3.5e-05 23.9 0.1 0.00061 19.9 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain Acetyltransf_1 PF00583.19 KFX95054.1 - 0.00058 19.8 0.0 0.0018 18.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Thioredoxin_8 PF13905.1 KFX95054.1 - 0.00084 19.4 0.1 0.0084 16.1 0.0 2.5 2 1 1 3 3 3 1 Thioredoxin-like Acetyltransf_7 PF13508.1 KFX95054.1 - 0.0065 16.6 0.0 0.023 14.8 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KFX95054.1 - 0.014 15.5 0.0 0.037 14.2 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX95054.1 - 0.038 14.1 0.0 0.15 12.2 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Redoxin PF08534.5 KFX95054.1 - 0.057 12.9 0.1 0.29 10.6 0.0 2.1 2 1 1 3 3 3 0 Redoxin Thioredoxin_7 PF13899.1 KFX95054.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Abhydrolase_3 PF07859.8 KFX95055.1 - 3.6e-30 105.1 0.0 4.4e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 KFX95055.1 - 2.9e-09 36.5 0.1 0.00075 18.8 0.1 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family COesterase PF00135.23 KFX95055.1 - 0.0011 17.8 0.0 0.0018 17.0 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 KFX95055.1 - 0.0012 18.0 0.0 0.0035 16.5 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 KFX95055.1 - 0.0059 16.3 0.0 0.0095 15.6 0.0 1.4 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 KFX95055.1 - 0.012 15.0 0.0 3.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Putative esterase DUF2974 PF11187.3 KFX95055.1 - 0.15 11.4 0.0 0.32 10.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Phytase PF02333.10 KFX95057.1 - 1.9e-57 194.7 4.7 3.4e-57 193.8 0.1 2.1 2 0 0 2 2 2 1 Phytase EGF_2 PF07974.8 KFX95057.1 - 2.3e-05 24.4 32.4 0.0048 17.0 6.8 2.5 2 0 0 2 2 2 2 EGF-like domain EGF PF00008.22 KFX95057.1 - 0.00065 19.6 21.0 0.0017 18.2 2.8 2.4 2 0 0 2 2 2 2 EGF-like domain Plasmod_Pvs28 PF06247.6 KFX95057.1 - 0.17 11.4 12.8 0.3 10.6 8.9 1.3 1 0 0 1 1 1 0 Plasmodium ookinete surface protein Pvs28 hEGF PF12661.2 KFX95057.1 - 1.5 9.0 13.2 1.4 9.1 2.2 2.7 2 0 0 2 2 2 0 Human growth factor-like EGF adh_short PF00106.20 KFX95058.1 - 1.4e-22 80.3 0.1 1.8e-22 80.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX95058.1 - 2.2e-09 37.2 0.0 2.8e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KFX95058.1 - 6.8e-06 25.1 0.0 7.9e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KFX95058.1 - 3.2e-05 23.4 0.0 0.00012 21.5 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KFX95058.1 - 0.00056 19.7 0.0 0.00069 19.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Glyco_tran_WecB PF03808.8 KFX95058.1 - 0.0042 16.4 0.0 0.077 12.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family Shikimate_DH PF01488.15 KFX95058.1 - 0.16 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ank_2 PF12796.2 KFX95059.1 - 2.5e-59 197.6 17.4 5e-14 52.4 0.1 5.7 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KFX95059.1 - 8.9e-34 113.6 7.3 1.1e-05 24.9 0.0 8.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 KFX95059.1 - 1.9e-32 110.5 8.7 6e-06 26.3 0.0 7.1 3 1 4 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFX95059.1 - 1.4e-31 108.2 2.1 2.5e-08 34.2 0.0 6.0 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX95059.1 - 1.1e-29 99.4 4.2 4.4e-05 23.3 0.0 7.5 7 0 0 7 7 7 7 Ankyrin repeat Glyco_hydro_26 PF02156.10 KFX95060.1 - 5.8e-77 259.2 2.6 6.8e-77 259.0 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Melibiase PF02065.13 KFX95061.1 - 1.3e-25 89.9 2.2 1.3e-19 70.2 0.0 3.8 1 1 1 2 2 2 2 Melibiase Raffinose_syn PF05691.7 KFX95061.1 - 0.019 12.5 0.2 0.026 12.0 0.1 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 Glyco_hydro_7 PF00840.15 KFX95062.1 - 8.8e-119 396.7 12.4 1.1e-118 396.3 8.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 FGGY_C PF02782.11 KFX95063.1 - 1.8e-69 233.3 2.7 3.2e-69 232.5 1.9 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KFX95063.1 - 4.6e-66 222.6 0.0 6.8e-66 222.0 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Aminotran_4 PF01063.14 KFX95064.1 - 2.3e-24 86.1 0.0 3.2e-24 85.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV DUF3830 PF12903.2 KFX95065.1 - 0.0013 18.1 0.1 0.0031 16.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3830) p450 PF00067.17 KFX95066.1 - 1.7e-51 175.2 0.0 2.3e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyoxalase PF00903.20 KFX95066.1 - 5.7e-10 39.2 0.0 1.1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KFX95066.1 - 2.6e-07 31.2 0.0 7.6e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KFX95066.1 - 0.0014 18.6 0.0 0.0056 16.6 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KFX95066.1 - 0.0015 18.4 0.0 0.58 10.0 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain AMP-binding PF00501.23 KFX95068.1 - 4.3e-48 163.7 0.0 6.1e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX95068.1 - 4.3e-09 37.2 0.0 8.9e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AA_permease_2 PF13520.1 KFX95069.1 - 2.1e-46 158.3 52.0 2.7e-46 157.9 36.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFX95069.1 - 3.7e-28 98.1 47.0 5.2e-28 97.6 32.6 1.1 1 0 0 1 1 1 1 Amino acid permease Aminotran_1_2 PF00155.16 KFX95070.1 - 2.6e-23 82.5 0.0 3.4e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KFX95070.1 - 0.00055 18.6 0.0 0.0014 17.2 0.0 1.5 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Fungal_trans_2 PF11951.3 KFX95071.1 - 4.6e-55 186.7 3.1 8.8e-55 185.8 2.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PolyA_pol PF01743.15 KFX95071.1 - 1.6e-20 73.5 0.2 1.5e-19 70.4 0.1 2.3 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 KFX95071.1 - 4.1e-06 26.2 0.5 1e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A DUF1517 PF07466.6 KFX95072.1 - 0.0021 17.0 1.3 0.0032 16.4 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) DUF1180 PF06679.7 KFX95072.1 - 0.15 11.9 1.4 0.3 10.9 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) COesterase PF00135.23 KFX95078.1 - 4.4e-93 312.8 0.0 6.3e-93 312.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family DUF1264 PF06884.6 KFX95078.1 - 3.2e-75 251.2 0.0 4.7e-75 250.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Abhydrolase_3 PF07859.8 KFX95078.1 - 0.0095 15.5 0.1 0.023 14.2 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold ABC_membrane PF00664.18 KFX95079.1 - 1.7e-71 240.8 27.8 4.2e-40 137.8 6.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFX95079.1 - 4.4e-65 218.1 0.1 2.6e-32 111.9 0.1 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFX95079.1 - 3.5e-14 52.5 0.0 7.4e-05 22.0 0.0 4.1 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFX95079.1 - 1.8e-11 44.5 0.3 0.021 14.8 0.0 4.3 4 0 0 4 4 4 3 AAA domain AAA_17 PF13207.1 KFX95079.1 - 2e-07 31.8 0.0 0.016 16.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 KFX95079.1 - 6.9e-07 28.7 0.4 0.019 14.4 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 KFX95079.1 - 6.5e-06 25.9 1.1 0.19 11.6 0.1 4.0 3 1 0 3 3 3 2 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 KFX95079.1 - 1.1e-05 24.6 0.0 0.17 11.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFX95079.1 - 1.7e-05 24.3 0.2 0.31 10.4 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.1 KFX95079.1 - 2.8e-05 24.2 3.7 1.3 9.2 0.1 4.3 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFX95079.1 - 4.4e-05 23.8 0.1 0.53 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFX95079.1 - 0.00013 22.0 4.2 0.052 13.5 0.2 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 KFX95079.1 - 0.00068 19.3 0.2 0.35 10.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KFX95079.1 - 0.00073 19.1 0.8 2 7.9 0.0 4.1 4 0 0 4 4 4 1 AAA domain Zeta_toxin PF06414.7 KFX95079.1 - 0.00093 18.3 0.1 0.22 10.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 KFX95079.1 - 0.0023 17.8 0.1 1.1 9.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 KFX95079.1 - 0.0031 16.1 0.3 0.96 7.9 0.0 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class APS_kinase PF01583.15 KFX95079.1 - 0.0066 16.1 0.2 3.6 7.2 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase Gtr1_RagA PF04670.7 KFX95079.1 - 0.033 13.3 0.1 3.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region MobB PF03205.9 KFX95079.1 - 0.038 13.7 0.3 2.8 7.6 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 KFX95079.1 - 0.078 13.1 0.9 38 4.4 0.1 3.7 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KFX95079.1 - 0.57 10.4 1.1 24 5.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Acetyltransf_3 PF13302.1 KFX95080.1 - 5.6e-27 94.6 0.0 1.9e-26 92.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX95080.1 - 0.0081 16.1 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MFS_1 PF07690.11 KFX95081.1 - 7.8e-11 41.2 60.4 1.3e-10 40.5 36.6 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Esterase PF00756.15 KFX95082.1 - 4.9e-16 58.9 0.1 6.4e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 KFX95082.1 - 1.1e-05 24.7 0.0 1.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KFX95082.1 - 0.00091 19.1 0.1 0.0011 18.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX95082.1 - 0.017 14.8 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0220 PF05255.6 KFX95083.1 - 2.4e-42 143.9 2.1 2.6e-42 143.8 1.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) RhodobacterPufX PF11511.3 KFX95083.1 - 0.074 12.4 1.9 0.37 10.2 0.1 2.1 2 0 0 2 2 2 0 Intrinsic membrane protein PufX PQQ_3 PF13570.1 KFX95083.1 - 0.076 13.3 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 PQQ-like domain SMI1_KNR4 PF09346.5 KFX95084.1 - 1e-33 116.0 0.0 1.6e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Tctex-1 PF03645.8 KFX95095.1 - 1.5e-19 69.6 0.0 2e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Tctex-1 family TPR_12 PF13424.1 KFX95096.1 - 9.3e-56 185.7 22.5 4.5e-11 42.5 0.1 6.9 2 2 6 8 8 8 8 Tetratricopeptide repeat TPR_10 PF13374.1 KFX95096.1 - 1.2e-51 171.2 5.9 2.6e-07 30.3 0.0 9.3 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_16 PF13432.1 KFX95096.1 - 2.8e-08 34.2 9.6 0.03 14.9 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFX95096.1 - 1e-06 28.0 15.7 0.35 10.7 0.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFX95096.1 - 7e-06 25.8 0.1 1.8 8.9 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFX95096.1 - 2.2e-05 24.0 8.2 1.7 8.3 0.0 5.6 4 3 2 6 6 6 2 TPR repeat TPR_2 PF07719.12 KFX95096.1 - 5.7e-05 22.7 14.8 1.2 9.1 0.1 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.9 KFX95096.1 - 0.00016 21.7 0.5 2.2 8.9 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 KFX95096.1 - 0.019 15.0 7.0 7.4 6.7 0.7 4.8 3 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KFX95096.1 - 0.094 12.3 17.9 7.8 6.2 0.0 7.4 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFX95096.1 - 0.2 12.3 9.9 5.5 7.9 0.1 6.0 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFX95096.1 - 0.31 11.3 4.4 0.78 10.1 0.1 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFX95096.1 - 6.7 7.4 8.7 52 4.6 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Activin_recp PF01064.18 KFX95099.1 - 0.014 15.9 8.1 0.037 14.6 3.6 2.8 2 1 1 3 3 3 0 Activin types I and II receptor domain Lamp PF01299.12 KFX95099.1 - 0.26 10.3 0.0 0.26 10.3 0.0 1.9 1 1 1 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Peptidase_S28 PF05577.7 KFX95100.1 - 6.1e-48 163.4 0.0 3.1e-47 161.1 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.6 KFX95100.1 - 0.00028 19.4 0.3 0.24 9.7 0.0 2.2 2 0 0 2 2 2 2 PS-10 peptidase S37 DUF4490 PF14892.1 KFX95100.1 - 0.18 11.4 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4490) CorA PF01544.13 KFX95105.1 - 8.6e-42 143.1 0.6 2.7e-41 141.5 0.4 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein TBCA PF02970.11 KFX95106.1 - 1.3e-20 73.2 13.8 1.3e-20 73.2 9.5 1.4 1 1 0 1 1 1 1 Tubulin binding cofactor A D123 PF07065.9 KFX95106.1 - 0.022 13.8 2.4 0.026 13.6 1.7 1.1 1 0 0 1 1 1 0 D123 MHCassoc_trimer PF08831.5 KFX95106.1 - 0.031 14.1 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain DUF3841 PF12952.2 KFX95106.1 - 0.052 13.0 0.8 0.06 12.8 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3841) DUF4363 PF14276.1 KFX95106.1 - 0.11 12.1 0.3 0.11 12.1 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) GLYCAM-1 PF05242.6 KFX95106.1 - 0.4 10.6 6.2 0.61 10.0 4.3 1.4 1 1 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) YkyA PF10368.4 KFX95106.1 - 0.46 9.7 18.5 0.096 12.0 8.1 1.9 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein DUF342 PF03961.8 KFX95106.1 - 0.5 8.7 9.4 0.6 8.4 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CDC37_N PF03234.9 KFX95106.1 - 0.51 10.6 8.3 0.79 10.0 5.8 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF4239 PF14023.1 KFX95106.1 - 0.63 9.3 3.6 0.78 9.0 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) SNARE PF05739.14 KFX95106.1 - 0.7 9.6 3.6 11 5.7 0.0 3.0 3 0 0 3 3 3 0 SNARE domain Fib_alpha PF08702.5 KFX95106.1 - 0.75 9.9 4.4 1.1 9.3 3.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DASH_Spc19 PF08287.6 KFX95106.1 - 0.77 9.3 9.6 0.75 9.3 5.7 1.6 1 1 0 1 1 1 0 Spc19 DUF1978 PF09321.5 KFX95106.1 - 0.8 9.0 13.7 1.4 8.2 9.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1978) CENP-Q PF13094.1 KFX95106.1 - 1 9.3 12.4 3.7 7.5 8.7 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit HSP70 PF00012.15 KFX95106.1 - 1.2 6.9 10.9 1.4 6.7 7.6 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF883 PF05957.8 KFX95106.1 - 1.2 9.5 7.4 8.5 6.8 5.1 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF3435 PF11917.3 KFX95106.1 - 1.3 7.6 6.8 1.5 7.4 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Syntaxin PF00804.20 KFX95106.1 - 1.4 9.1 8.2 2.7 8.1 5.7 1.6 1 1 0 1 1 1 0 Syntaxin Exonuc_VII_L PF02601.10 KFX95106.1 - 1.4 8.0 7.5 1.7 7.7 5.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.14 KFX95106.1 - 1.5 6.5 7.1 1.7 6.4 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CHASE3 PF05227.8 KFX95106.1 - 1.6 8.3 10.5 1.9 8.1 7.3 1.1 1 0 0 1 1 1 0 CHASE3 domain APG6 PF04111.7 KFX95106.1 - 1.8 7.5 14.2 0.69 8.8 8.4 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF2570 PF10828.3 KFX95106.1 - 1.9 8.0 5.4 3.2 7.3 3.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) HAUS6_N PF14661.1 KFX95106.1 - 2 7.7 7.9 2.3 7.4 5.5 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus IncA PF04156.9 KFX95106.1 - 2.1 7.8 14.7 4.2 6.9 10.2 1.5 1 1 0 1 1 1 0 IncA protein FlgN PF05130.7 KFX95106.1 - 2.6 8.2 11.1 0.81 9.9 5.5 1.6 1 1 1 2 2 2 0 FlgN protein Spectrin PF00435.16 KFX95106.1 - 4.2 7.7 11.1 2.1 8.6 3.6 2.0 1 1 0 1 1 1 0 Spectrin repeat DUF4463 PF14703.1 KFX95106.1 - 4.6 7.8 8.7 14 6.3 6.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4463) TMPIT PF07851.8 KFX95106.1 - 6.1 5.8 6.0 7 5.6 4.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4404 PF14357.1 KFX95106.1 - 8.7 6.8 11.8 2 8.8 1.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DcpS_C PF11969.3 KFX95109.1 - 3.9e-29 101.2 0.1 9e-29 100.0 0.1 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 KFX95109.1 - 1.4e-18 67.3 0.0 2.1e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Pex14_N PF04695.8 KFX95110.1 - 0.016 15.2 2.0 0.022 14.7 1.4 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2648 PF10855.3 KFX95110.1 - 0.049 13.0 0.9 0.088 12.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) RIC3 PF15361.1 KFX95110.1 - 0.052 13.7 0.1 0.061 13.5 0.0 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Myb_Cef PF11831.3 KFX95111.1 - 5.2e-55 186.1 4.7 5.2e-55 186.1 3.2 2.9 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 KFX95111.1 - 2.5e-20 72.2 4.9 1.5e-09 37.7 0.4 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFX95111.1 - 9.1e-19 67.3 6.5 1.1e-13 51.0 1.2 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.3 KFX95111.1 - 0.33 10.8 3.3 0.55 10.1 0.0 2.9 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Aldedh PF00171.17 KFX95112.1 - 3.1e-139 464.2 0.0 3.7e-139 464.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFX95112.1 - 5.9e-06 25.2 0.0 9.1e-06 24.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Glyco_trans_2_3 PF13632.1 KFX95120.1 - 4.5e-17 62.4 0.7 1.3e-16 60.9 0.5 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Ycf1 PF05758.7 KFX95124.1 - 2.3 5.7 7.9 3.2 5.3 5.5 1.1 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 KFX95124.1 - 6.9 4.5 13.3 9.4 4.1 9.2 1.1 1 0 0 1 1 1 0 CDC45-like protein ABC2_membrane PF01061.19 KFX95131.1 - 1.5e-84 282.3 61.1 1.7e-43 148.2 14.3 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KFX95131.1 - 9.6e-33 113.3 0.0 8.4e-17 61.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KFX95131.1 - 5.6e-32 109.4 8.0 2.3e-30 104.2 0.0 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KFX95131.1 - 1.1e-15 57.4 0.1 4.3e-15 55.5 0.0 2.0 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 KFX95131.1 - 9.1e-08 31.5 47.1 5.4e-06 25.6 12.1 3.0 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.1 KFX95131.1 - 1.2e-06 28.0 0.0 0.0019 17.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFX95131.1 - 3.4e-06 27.1 0.4 0.044 13.7 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 KFX95131.1 - 6e-06 25.5 0.1 0.00019 20.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KFX95131.1 - 2.2e-05 25.2 0.0 0.043 14.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KFX95131.1 - 4.2e-05 23.4 0.0 0.028 14.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFX95131.1 - 5e-05 23.6 0.0 0.041 14.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KFX95131.1 - 0.00025 20.5 0.5 0.033 13.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 KFX95131.1 - 0.00034 20.6 0.2 1 9.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 KFX95131.1 - 0.00081 18.8 1.0 0.057 12.8 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 KFX95131.1 - 0.0039 16.9 0.4 3 7.6 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain SMC_N PF02463.14 KFX95131.1 - 0.0041 16.3 0.0 0.62 9.2 0.0 3.4 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KFX95131.1 - 0.0043 17.1 0.5 1.1 9.3 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_21 PF13304.1 KFX95131.1 - 0.0051 16.8 0.0 1.5 8.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 KFX95131.1 - 0.012 15.2 0.9 3.6 7.2 0.2 2.6 2 0 0 2 2 2 0 NACHT domain AAA PF00004.24 KFX95131.1 - 0.013 15.6 0.1 4.5 7.4 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFX95131.1 - 0.12 12.1 0.1 11 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Miro PF08477.8 KFX95131.1 - 0.16 12.4 0.0 36 4.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 KFX95131.1 - 0.45 9.9 1.8 6.3 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Zn_clus PF00172.13 KFX95132.1 - 6.7e-07 29.1 13.0 6.7e-07 29.1 9.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX95132.1 - 0.059 12.2 0.1 0.12 11.2 0.1 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Glyco_hydro_67M PF07488.7 KFX95142.1 - 4.5e-152 505.6 0.1 6.5e-152 505.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 KFX95142.1 - 2.6e-94 314.8 4.3 4.1e-94 314.2 3.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 KFX95142.1 - 1.7e-29 102.3 0.0 2.8e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.10 KFX95142.1 - 0.00035 21.0 0.0 0.00089 19.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Pkinase PF00069.20 KFX95143.1 - 7e-62 208.9 0.0 9.6e-62 208.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX95143.1 - 1.2e-29 103.1 0.0 2.7e-29 102.0 0.0 1.6 1 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX95143.1 - 0.016 14.1 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KFX95143.1 - 0.15 11.7 0.0 0.35 10.5 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Sugar_tr PF00083.19 KFX95144.1 - 1.6e-81 274.2 27.4 5.5e-80 269.1 19.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX95144.1 - 2.1e-30 105.6 42.5 6.1e-29 100.8 24.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Actin PF00022.14 KFX95145.1 - 3.3e-116 387.9 0.0 4.1e-116 387.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KFX95145.1 - 0.0036 15.9 0.0 0.012 14.1 0.0 1.9 1 1 0 1 1 1 1 MreB/Mbl protein Asp_Glu_race PF01177.17 KFX95146.1 - 2.3e-20 73.4 0.0 3.1e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Hexapep PF00132.19 KFX95147.1 - 1.3e-07 30.8 9.2 8.8e-05 21.8 0.3 4.5 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KFX95147.1 - 5.3e-05 22.6 12.0 0.00045 19.7 0.4 4.1 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 KFX95147.1 - 0.15 10.5 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase PMI_typeI PF01238.16 KFX95148.1 - 3.3e-141 470.5 0.0 3.9e-141 470.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I FAD_binding_3 PF01494.14 KFX95149.1 - 9e-19 67.7 0.0 3.7e-18 65.7 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KFX95149.1 - 2.2e-08 33.6 0.1 7.3e-05 22.0 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KFX95149.1 - 0.0067 15.3 0.1 0.022 13.6 0.0 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KFX95149.1 - 0.026 14.5 0.1 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFX95149.1 - 0.046 12.6 0.2 4.8 5.9 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFX95149.1 - 0.11 12.8 2.5 8.1 6.9 0.1 3.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase RTA1 PF04479.8 KFX95151.1 - 2.7e-43 148.0 0.4 3.9e-43 147.5 0.3 1.2 1 0 0 1 1 1 1 RTA1 like protein TctB PF07331.6 KFX95151.1 - 0.076 12.6 6.2 0.098 12.3 0.9 2.5 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family MatE PF01554.13 KFX95151.1 - 9 5.8 13.0 0.14 11.8 2.5 2.6 3 1 0 3 3 3 0 MatE PhyH PF05721.8 KFX95152.1 - 0.0001 22.4 0.1 0.00027 21.0 0.1 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1049 PF06305.6 KFX95156.1 - 4.1 6.9 7.4 1 8.8 3.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) ABC_membrane_3 PF13748.1 KFX95157.1 - 0.0093 15.0 0.9 0.018 14.0 0.6 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region Sensor PF13796.1 KFX95157.1 - 1.3 8.5 24.0 1.5 8.3 0.0 3.6 3 0 0 3 3 3 0 Putative sensor FtsX PF02687.16 KFX95157.1 - 3.6 7.3 13.3 5.2 6.8 3.8 3.0 3 0 0 3 3 3 0 FtsX-like permease family DUF3487 PF11990.3 KFX95157.1 - 4.7 6.6 11.1 0.093 12.1 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3487) DUF1395 PF07160.7 KFX95161.1 - 0.058 12.8 0.0 0.07 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) zf-3CxxC PF13695.1 KFX95163.1 - 6.2e-28 96.9 1.0 1.2e-27 96.0 0.7 1.5 1 0 0 1 1 1 1 Zinc-binding domain F-box-like PF12937.2 KFX95163.1 - 2.9e-07 30.1 0.2 5.7e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX95163.1 - 0.00036 20.1 0.1 0.0012 18.4 0.1 1.9 1 0 0 1 1 1 1 F-box domain Rad52_Rad22 PF04098.10 KFX95163.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Rad52/22 family double-strand break repair protein Ank_2 PF12796.2 KFX95164.1 - 7.8e-24 83.8 0.5 1.2e-14 54.4 0.1 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFX95164.1 - 1.7e-21 74.8 9.1 2.8e-08 33.1 0.5 6.3 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 KFX95164.1 - 3.1e-17 62.2 3.1 3.3e-08 33.5 0.1 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFX95164.1 - 5.2e-17 61.8 1.6 4.1e-07 30.3 0.1 4.3 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX95164.1 - 5.7e-16 57.0 3.4 6.6e-05 22.7 0.1 6.2 5 1 0 5 5 5 4 Ankyrin repeat F-box-like PF12937.2 KFX95164.1 - 2.6e-05 23.8 0.0 5.1e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX95164.1 - 0.017 14.7 0.1 0.036 13.7 0.1 1.5 1 0 0 1 1 1 0 F-box domain Beta-lactamase PF00144.19 KFX95165.1 - 4.1e-34 118.0 0.0 5.8e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Acetyltransf_1 PF00583.19 KFX95165.1 - 0.025 14.5 0.0 0.069 13.1 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family DUF1748 PF08520.5 KFX95169.1 - 1.6e-33 114.1 0.2 1.9e-33 113.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PK PF00224.16 KFX95170.1 - 2.8e-167 555.6 6.3 4.4e-167 555.0 4.4 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KFX95170.1 - 4.5e-29 100.3 0.0 2.3e-28 98.0 0.0 2.3 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 KFX95170.1 - 0.00014 20.8 2.5 0.0013 17.7 0.3 2.3 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 KFX95170.1 - 0.0075 15.1 0.1 0.045 12.6 0.0 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain TFIIA PF03153.8 KFX95174.1 - 3.5e-83 280.6 67.8 2.3e-49 169.2 19.8 2.3 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit WD40 PF00400.27 KFX95176.1 - 1.7e-23 81.5 20.1 3.5e-06 26.6 0.1 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KFX95176.1 - 9.8e-07 28.6 0.2 0.00023 20.9 0.0 2.6 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 KFX95176.1 - 0.023 14.4 4.2 0.27 10.9 0.3 3.6 3 1 1 4 4 4 0 Transcription factor IIIC subunit delta N-term Methyltransf_23 PF13489.1 KFX95177.1 - 2e-14 53.6 0.0 3e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX95177.1 - 1.7e-08 34.2 0.0 1.2e-07 31.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX95177.1 - 4.4e-07 30.4 0.0 3e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX95177.1 - 6.3e-06 26.6 0.0 1.5e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX95177.1 - 0.00015 22.1 0.0 0.00052 20.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX95177.1 - 0.00043 19.7 0.0 0.00073 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 KFX95177.1 - 0.00063 19.0 0.0 0.00093 18.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_16 PF10294.4 KFX95177.1 - 0.0037 16.7 0.0 0.0071 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.12 KFX95177.1 - 0.0057 15.7 0.0 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 KFX95177.1 - 0.021 14.8 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 KFX95177.1 - 0.033 13.3 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 KFX95177.1 - 0.05 12.6 0.0 0.15 11.0 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase DUF1156 PF06634.7 KFX95177.1 - 0.098 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) Methyltransf_25 PF13649.1 KFX95177.1 - 0.12 12.7 0.0 0.81 10.0 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain DUF3293 PF11697.3 KFX95181.1 - 0.03 14.4 0.1 0.037 14.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3293) SspP PF08179.7 KFX95181.1 - 0.054 13.6 0.3 0.096 12.9 0.2 1.4 1 0 0 1 1 1 0 Small acid-soluble spore protein P family BORG_CEP PF14957.1 KFX95181.1 - 0.11 13.4 0.3 0.11 13.3 0.2 1.0 1 0 0 1 1 1 0 Cdc42 effector AAA PF00004.24 KFX95182.1 - 1.3e-41 141.8 0.0 2.2e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFX95182.1 - 5.7e-07 29.7 0.1 0.00022 21.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KFX95182.1 - 1.4e-06 28.2 0.0 2.6e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KFX95182.1 - 1e-05 24.6 0.0 1.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KFX95182.1 - 2e-05 24.3 0.1 7.1e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFX95182.1 - 0.00027 21.0 0.1 0.00093 19.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KFX95182.1 - 0.00029 19.9 0.0 0.00051 19.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 KFX95182.1 - 0.0013 18.7 0.8 0.0041 17.1 0.1 2.3 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 KFX95182.1 - 0.0019 17.9 0.2 0.34 10.5 0.1 3.0 2 1 1 3 3 3 1 NACHT domain AAA_14 PF13173.1 KFX95182.1 - 0.0022 17.8 0.0 0.0042 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFX95182.1 - 0.0027 17.6 0.0 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFX95182.1 - 0.0043 17.8 0.2 0.012 16.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KFX95182.1 - 0.0054 16.1 0.0 0.014 14.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KFX95182.1 - 0.0065 16.2 0.3 0.015 14.9 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 KFX95182.1 - 0.0091 15.1 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KFX95182.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KFX95182.1 - 0.013 15.0 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 KFX95182.1 - 0.031 13.4 0.2 0.44 9.6 0.1 2.2 1 1 1 2 2 2 0 KaiC TIP49 PF06068.8 KFX95182.1 - 0.035 12.8 1.6 0.046 12.4 0.1 1.8 2 1 0 2 2 2 0 TIP49 C-terminus RNA_helicase PF00910.17 KFX95182.1 - 0.042 14.0 0.0 0.082 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 KFX95182.1 - 0.042 12.7 0.0 0.068 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Mg_chelatase PF01078.16 KFX95182.1 - 0.055 12.6 0.1 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 KFX95182.1 - 0.092 11.9 1.1 0.21 10.7 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.1 KFX95182.1 - 0.093 12.2 1.3 0.14 11.7 0.2 1.8 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KFX95182.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 KFX95182.1 - 0.12 12.6 0.5 0.85 9.9 0.4 2.4 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 KFX95182.1 - 0.13 11.6 4.4 0.25 10.7 0.3 2.6 2 1 0 3 3 3 0 AAA domain Ribosomal_S7 PF00177.16 KFX95184.1 - 3e-39 133.9 1.8 3.7e-39 133.6 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S25 PF03297.10 KFX95185.1 - 2.6e-40 136.6 3.5 2.9e-40 136.5 2.4 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.2 KFX95185.1 - 0.0084 15.7 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 MarR family HTH_DeoR PF08220.7 KFX95185.1 - 0.011 15.2 0.1 0.015 14.8 0.1 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_24 PF13412.1 KFX95185.1 - 0.015 14.6 0.1 0.024 14.0 0.1 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Rrf2 PF02082.15 KFX95185.1 - 0.034 14.2 0.0 0.05 13.7 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator Cyt-b5 PF00173.23 KFX95186.1 - 6.1e-09 35.5 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HAND PF09110.6 KFX95186.1 - 0.097 13.0 0.6 0.24 11.8 0.4 1.7 1 0 0 1 1 1 0 HAND DEAD PF00270.24 KFX95187.1 - 7.4e-33 113.4 0.8 2.8e-15 56.2 0.1 2.4 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX95187.1 - 9.5e-21 73.4 0.1 2.1e-20 72.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX95187.1 - 1.7e-06 27.9 2.6 0.0001 22.2 0.0 3.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit PIGA PF08288.7 KFX95188.1 - 1.2e-46 156.9 4.9 1.8e-46 156.4 1.3 2.6 3 0 0 3 3 3 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 KFX95188.1 - 1.5e-28 99.4 0.0 2.3e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KFX95188.1 - 8e-18 64.8 0.1 1.4e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KFX95188.1 - 3.4e-16 59.4 0.6 6.2e-16 58.6 0.4 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 KFX95188.1 - 4.4e-14 52.9 0.0 1e-13 51.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 KFX95188.1 - 1.9e-06 27.7 0.3 3.6e-06 26.8 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 KFX95188.1 - 0.00088 19.4 0.0 0.0025 18.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_hydro_10 PF00331.15 KFX95189.1 - 9.1e-103 343.6 0.0 1e-102 343.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.10 KFX95189.1 - 0.0089 15.1 0.1 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase Cellulase-like PF12876.2 KFX95189.1 - 0.037 14.4 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Sugar-binding cellulase-like DUF59 PF01883.14 KFX95189.1 - 0.099 12.6 0.2 0.27 11.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF59 NPR3 PF03666.8 KFX95190.1 - 2e-129 432.1 0.2 3.1e-129 431.4 0.1 1.3 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 CHCH PF06747.8 KFX95191.1 - 2.9e-05 23.8 0.9 4.9e-05 23.1 0.7 1.4 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 KFX95191.1 - 0.035 14.1 2.6 0.31 11.1 2.1 1.9 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 KFX95191.1 - 0.19 11.5 1.9 0.8 9.5 1.3 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 KFX95191.1 - 0.2 11.6 2.2 2 8.5 0.2 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) GFA PF04828.9 KFX95192.1 - 2.6e-11 43.3 0.5 4e-11 42.7 0.3 1.4 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Pex14_N PF04695.8 KFX95193.1 - 0.16 12.0 3.4 0.24 11.4 2.4 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.4 KFX95193.1 - 6 5.0 19.2 6.7 4.8 13.3 1.0 1 0 0 1 1 1 0 Transmembrane protein UCR_Fe-S_N PF10399.4 KFX95194.1 - 2.2 7.5 26.6 1.9 7.7 0.4 6.1 5 0 0 5 5 5 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Glyco_hydro_3_C PF01915.17 KFX95197.1 - 5.4e-27 94.7 0.3 3.5e-26 92.1 0.2 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFX95197.1 - 1.1e-25 89.3 1.4 1.1e-25 89.3 0.9 1.6 2 0 0 2 2 2 1 Fibronectin type III-like domain CARDB PF07705.6 KFX95197.1 - 0.08 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 CARDB NPCBM_assoc PF10633.4 KFX95197.1 - 0.11 12.5 0.5 0.46 10.5 0.4 2.0 1 1 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Ribosomal_L34e PF01199.13 KFX95198.1 - 0.16 12.2 0.9 0.29 11.4 0.6 1.5 1 1 0 1 1 1 0 Ribosomal protein L34e MAGE_N PF12440.3 KFX95198.1 - 0.17 12.1 1.3 0.27 11.5 0.9 1.3 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal MFS_1 PF07690.11 KFX95199.1 - 1.2e-41 142.6 40.1 1.2e-41 142.6 27.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX95199.1 - 3.5e-08 32.4 26.1 1.2e-07 30.6 18.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 KFX95199.1 - 0.027 12.6 6.8 0.12 10.5 4.7 2.0 1 1 0 1 1 1 0 Transmembrane secretion effector ATP-synt_8 PF00895.15 KFX95199.1 - 8 6.7 7.2 19 5.5 0.3 2.9 2 0 0 2 2 2 0 ATP synthase protein 8 DEAD PF00270.24 KFX95200.1 - 2.7e-44 150.6 0.6 2.9e-42 144.0 0.1 2.1 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX95200.1 - 3.7e-23 81.1 0.0 1.5e-22 79.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX95200.1 - 9.1e-06 25.6 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KFX95200.1 - 0.0076 16.3 1.7 0.16 12.1 1.1 2.9 2 2 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KFX95200.1 - 0.016 14.7 0.0 6.8 6.1 0.1 2.5 1 1 1 2 2 2 0 AAA domain Helicase_RecD PF05127.9 KFX95200.1 - 0.027 14.1 0.0 0.062 12.9 0.0 1.6 1 0 0 1 1 1 0 Helicase SecA_DEAD PF07517.9 KFX95200.1 - 0.029 13.6 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain OB_NTP_bind PF07717.11 KFX95201.1 - 4.3e-27 94.2 0.0 9.9e-27 93.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFX95201.1 - 2.9e-23 81.8 0.1 7.7e-23 80.4 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFX95201.1 - 8.1e-12 44.8 0.0 1.7e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFX95201.1 - 5.1e-07 29.3 0.3 3.1e-06 26.7 0.2 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFX95201.1 - 1.3e-05 25.3 0.0 4e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 KFX95201.1 - 0.00017 21.1 0.1 0.00049 19.5 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 KFX95201.1 - 0.0034 17.1 0.1 0.0081 15.9 0.1 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.10 KFX95201.1 - 0.017 14.9 1.5 0.75 9.5 0.0 2.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit PALP PF00291.20 KFX95208.1 - 0.00025 20.3 0.1 0.00035 19.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FlxA PF14282.1 KFX95209.1 - 0.0004 20.3 0.8 0.0014 18.5 0.5 1.9 1 0 0 1 1 1 1 FlxA-like protein Enkurin PF13864.1 KFX95209.1 - 0.24 11.6 0.9 0.55 10.4 0.7 1.5 1 0 0 1 1 1 0 Calmodulin-binding Pkinase PF00069.20 KFX95210.1 - 7.1e-07 28.6 0.0 1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KFX95210.1 - 0.00038 19.4 0.0 0.00053 19.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 KFX95210.1 - 0.00065 18.8 0.0 0.00093 18.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFX95210.1 - 0.043 12.8 0.2 0.078 12.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_72 PF03198.9 KFX95211.1 - 4.7e-101 337.8 0.0 6.3e-101 337.4 0.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase DUF3605 PF12239.3 KFX95214.1 - 1.5e-51 174.4 0.1 6.8e-32 110.5 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3605) FolB PF02152.13 KFX95215.1 - 2.7e-19 69.3 0.1 2.2e-15 56.7 0.1 2.5 2 0 0 2 2 2 2 Dihydroneopterin aldolase FAR1 PF03101.10 KFX95215.1 - 0.00059 20.3 1.0 0.0012 19.3 0.7 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain Fungal_trans PF04082.13 KFX95216.1 - 4.2e-19 68.4 0.0 7.8e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ING PF12998.2 KFX95217.1 - 6.2e-21 74.6 2.1 8.8e-21 74.1 1.4 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KFX95217.1 - 6.1e-08 32.2 7.8 1.1e-07 31.4 5.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-RanBP PF00641.13 KFX95217.1 - 0.011 14.8 0.9 0.022 13.8 0.6 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Hist_deacetyl PF00850.14 KFX95218.1 - 1.4e-80 270.9 0.5 2.4e-80 270.1 0.1 1.5 2 0 0 2 2 2 1 Histone deacetylase domain tRNA-synt_His PF13393.1 KFX95219.1 - 2.7e-40 138.3 0.0 8.8e-34 116.9 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 KFX95219.1 - 1.7e-18 66.8 0.0 2.6e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFX95219.1 - 2.3e-11 43.4 0.0 4.4e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 KFX95219.1 - 3.6e-05 22.6 0.0 0.00077 18.3 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) Ribosomal_60s PF00428.14 KFX95219.1 - 0.15 12.4 0.3 0.15 12.4 0.2 3.3 4 0 0 4 4 4 0 60s Acidic ribosomal protein POR_N PF01855.14 KFX95221.1 - 0.37 10.2 4.5 0.57 9.6 3.1 1.2 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Polyketide_cyc2 PF10604.4 KFX95222.1 - 9.8e-10 38.7 5.2 1.9e-09 37.8 3.6 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 KFX95222.1 - 0.0067 16.4 0.0 0.012 15.6 0.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport TcpQ PF10671.4 KFX95222.1 - 0.084 12.7 0.1 0.18 11.7 0.1 1.6 1 1 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q Nop14 PF04147.7 KFX95223.1 - 0.76 7.6 19.3 0.99 7.2 13.4 1.2 1 0 0 1 1 1 0 Nop14-like family Pox_RNA_Pol_19 PF05320.7 KFX95223.1 - 1.4 8.6 11.6 2.4 7.8 8.0 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Mpp10 PF04006.7 KFX95223.1 - 1.6 7.0 23.5 2 6.6 16.3 1.1 1 0 0 1 1 1 0 Mpp10 protein CENP-T PF15511.1 KFX95223.1 - 2.2 7.4 12.0 2.5 7.2 8.3 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Sigma70_ner PF04546.8 KFX95223.1 - 3.7 7.0 16.0 7.1 6.1 11.1 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region Daxx PF03344.10 KFX95223.1 - 3.7 5.8 23.0 4.4 5.6 15.9 1.0 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 KFX95223.1 - 5.4 5.9 19.9 6.1 5.8 13.8 1.1 1 0 0 1 1 1 0 BUD22 Aminotran_4 PF01063.14 KFX95224.1 - 5.9e-29 101.1 0.0 8.3e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Pkinase PF00069.20 KFX95225.1 - 3.3e-14 52.6 0.0 1.2e-13 50.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX95225.1 - 4.8e-06 25.8 0.0 1.8e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase ParcG PF10274.4 KFX95225.1 - 0.083 12.7 1.2 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Parkin co-regulated protein Helicase_C PF00271.26 KFX95228.1 - 3.2e-09 36.5 0.2 5e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Catalase-rel PF06628.7 KFX95228.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Catalase-related immune-responsive GRP PF07172.6 KFX95228.1 - 0.3 11.5 25.1 0.22 12.0 16.6 1.4 1 1 0 1 1 1 0 Glycine rich protein family Ish1 PF10281.4 KFX95230.1 - 0.15 12.1 0.2 0.34 11.0 0.1 1.6 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein GFA PF04828.9 KFX95231.1 - 2.2e-18 65.9 0.1 3.2e-18 65.4 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 KFX95231.1 - 0.53 9.8 0.0 0.53 9.8 0.0 2.8 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.1 KFX95231.1 - 0.89 9.2 0.0 0.89 9.2 0.0 3.0 3 1 0 3 3 3 0 Nudix N-terminal zf-ribbon_3 PF13248.1 KFX95231.1 - 1.5 8.1 10.6 0.64 9.3 0.2 3.3 3 1 0 3 3 3 0 zinc-ribbon domain Lar_restr_allev PF14354.1 KFX95231.1 - 1.6 9.0 5.4 18 5.7 0.0 2.3 1 1 0 2 2 2 0 Restriction alleviation protein Lar ADH_N PF08240.7 KFX95232.1 - 5.6e-29 100.0 1.7 8.5e-29 99.5 1.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Roughex PF06020.6 KFX95236.1 - 3.5 6.1 17.9 0.53 8.9 10.0 1.3 1 1 0 1 1 1 0 Drosophila roughex protein DNA_pol_A_exo1 PF01612.15 KFX95237.1 - 0.00029 20.3 0.0 0.00029 20.3 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease DUF607 PF04678.8 KFX95238.1 - 3.9e-43 147.4 0.4 3.9e-43 147.4 0.3 3.1 3 1 0 3 3 3 1 Protein of unknown function, DUF607 TFIIH_BTF_p62_N PF08567.6 KFX95240.1 - 1.7e-24 85.2 0.1 4.8e-24 83.8 0.0 1.8 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.12 KFX95240.1 - 1.4e-23 82.3 5.3 1.1e-13 50.7 0.2 2.7 2 0 0 2 2 2 2 BSD domain Transket_pyr PF02779.19 KFX95241.1 - 2.6e-63 212.7 0.0 4.5e-63 211.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KFX95241.1 - 2.6e-55 187.2 0.0 3.9e-55 186.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component NTP_transferase PF00483.18 KFX95242.1 - 7.8e-48 162.9 0.0 1.5e-47 162.0 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 KFX95242.1 - 6.5e-16 57.0 12.3 1e-09 37.4 1.3 4.2 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KFX95242.1 - 4.4e-11 43.1 0.0 6.3e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KFX95242.1 - 1.1e-06 28.0 1.3 1.1e-06 28.0 0.9 3.0 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase Anp1 PF03452.9 KFX95247.1 - 8e-108 359.6 0.0 1e-107 359.3 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 KFX95247.1 - 0.035 13.7 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 FixQ PF05545.6 KFX95247.1 - 0.099 12.3 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Peptidase_C1_2 PF03051.10 KFX95250.1 - 1.2e-152 508.5 0.0 1.3e-152 508.3 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 KFX95250.1 - 3.7e-08 33.5 0.1 0.0012 18.7 0.1 2.3 2 0 0 2 2 2 2 Papain family cysteine protease AraC_N PF06719.8 KFX95251.1 - 0.0017 17.6 0.0 0.0051 16.1 0.0 1.6 1 1 1 2 2 2 1 AraC-type transcriptional regulator N-terminus Peptidase_M19 PF01244.16 KFX95253.1 - 2.8e-59 200.6 0.0 5.5e-59 199.6 0.0 1.4 1 1 1 2 2 2 1 Membrane dipeptidase (Peptidase family M19) GvpH PF05455.6 KFX95255.1 - 0.047 13.3 0.2 0.054 13.1 0.2 1.1 1 0 0 1 1 1 0 GvpH DUF4643 PF15485.1 KFX95255.1 - 0.083 12.3 0.0 0.089 12.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) FA_hydroxylase PF04116.8 KFX95264.1 - 0.00024 21.4 23.7 0.00024 21.4 16.5 2.5 2 2 1 3 3 3 1 Fatty acid hydroxylase superfamily Metallophos PF00149.23 KFX95264.1 - 0.018 14.4 2.0 0.073 12.4 0.2 2.2 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase Ank_2 PF12796.2 KFX95265.1 - 1.1e-21 77.0 4.1 1.9e-11 44.1 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFX95265.1 - 8.2e-14 50.6 0.4 3.8e-07 29.5 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KFX95265.1 - 1.1e-13 50.9 0.4 5.8e-07 29.5 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFX95265.1 - 1.6e-12 47.5 1.4 2.5e-06 27.8 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX95265.1 - 9.8e-08 31.5 0.1 0.0015 18.6 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Imm29 PF15575.1 KFX95265.1 - 0.012 15.2 0.1 0.014 15.0 0.1 1.1 1 0 0 1 1 1 0 Immunity protein 29 MRG PF05712.8 KFX95271.1 - 0.18 10.6 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 MRG DUF2236 PF09995.4 KFX95272.1 - 7.7e-40 136.6 0.1 1e-39 136.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Herpes_US12 PF05363.7 KFX95273.1 - 0.061 13.8 0.4 0.17 12.4 0.0 1.8 2 0 0 2 2 2 0 Herpesvirus US12 family Ferric_reduct PF01794.14 KFX95274.1 - 2e-11 44.0 5.2 2e-11 44.0 3.6 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KFX95274.1 - 8.4e-10 38.4 0.0 2.2e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KFX95274.1 - 7.9e-05 22.6 0.0 0.00018 21.4 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain zf-C2H2 PF00096.21 KFX95278.1 - 0.013 15.8 6.1 1.6 9.2 1.0 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX95278.1 - 0.091 13.1 0.3 0.091 13.1 0.2 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Aldedh PF00171.17 KFX95280.1 - 8.6e-180 597.9 0.6 9.7e-180 597.8 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KFX95280.1 - 0.0016 17.6 0.0 0.44 9.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) MFS_1 PF07690.11 KFX95281.1 - 5.7e-47 160.1 30.5 6.2e-45 153.4 13.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX95281.1 - 5.5e-19 68.0 11.1 5.5e-19 68.0 7.7 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 KFX95281.1 - 1.3e-05 23.6 2.3 2.1e-05 22.9 1.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KFX95281.1 - 0.00047 18.4 0.8 0.00078 17.6 0.6 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector PUCC PF03209.10 KFX95281.1 - 0.0054 15.5 4.0 0.0054 15.5 2.8 2.8 2 1 1 3 3 3 1 PUCC protein OATP PF03137.15 KFX95281.1 - 0.098 10.6 7.6 0.77 7.7 0.3 2.6 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Arginase PF00491.16 KFX95282.1 - 1.4e-92 309.8 0.0 1.7e-92 309.6 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KFX95282.1 - 0.062 13.4 0.1 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 UPF0489 domain Fungal_trans_2 PF11951.3 KFX95283.1 - 8.5e-51 172.7 9.2 1.1e-50 172.3 6.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX95283.1 - 4.1e-09 36.1 9.8 7.6e-09 35.3 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PS-DH PF14765.1 KFX95283.1 - 0.015 14.4 0.4 0.057 12.5 0.1 1.9 1 1 1 2 2 2 0 Polyketide synthase dehydratase DUF2072 PF09845.4 KFX95283.1 - 0.18 11.7 2.3 0.35 10.7 1.6 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) Amidase PF01425.16 KFX95285.1 - 8.8e-93 311.5 0.0 1.1e-92 311.1 0.0 1.1 1 0 0 1 1 1 1 Amidase V-ATPase_H_C PF11698.3 KFX95285.1 - 0.03 14.2 0.0 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 V-ATPase subunit H MBOAT_2 PF13813.1 KFX95286.1 - 2.5e-18 65.9 2.9 7.7e-18 64.3 2.0 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family adh_short PF00106.20 KFX95286.1 - 2.9e-10 40.3 0.1 1.1e-09 38.4 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFX95286.1 - 1.6e-05 24.6 0.1 5.1e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KFX95286.1 - 3.7e-05 23.6 0.0 0.00012 21.9 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans PF04082.13 KFX95287.1 - 5.3e-19 68.1 0.0 9.8e-19 67.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX95287.1 - 7.7e-07 28.9 11.0 1.3e-06 28.2 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KFX95289.1 - 9.7e-51 172.7 0.0 1.4e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.1 KFX95290.1 - 3.5e-51 174.0 59.5 4.4e-51 173.7 41.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFX95290.1 - 1.1e-22 80.0 50.2 1.5e-22 79.5 34.8 1.1 1 0 0 1 1 1 1 Amino acid permease BUD22 PF09073.5 KFX95313.1 - 9.5 5.1 23.0 0.34 9.9 9.2 2.1 2 0 0 2 2 2 0 BUD22 MgsA_C PF12002.3 KFX95314.1 - 2.3e-58 196.6 0.0 3.6e-58 195.9 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 KFX95314.1 - 2.8e-12 46.9 0.0 7.3e-12 45.6 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFX95314.1 - 3.7e-09 35.9 0.0 1.2e-08 34.2 0.0 1.7 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KFX95314.1 - 7.1e-06 25.3 0.1 0.034 13.2 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KFX95314.1 - 4e-05 23.2 0.0 0.0001 21.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activat PF00158.21 KFX95314.1 - 5.4e-05 22.7 0.1 0.0015 18.0 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 KFX95314.1 - 0.0001 22.0 0.1 0.0094 15.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFX95314.1 - 0.00097 19.2 0.3 0.0069 16.5 0.2 2.3 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 KFX95314.1 - 0.0033 17.0 0.0 0.011 15.3 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFX95314.1 - 0.0038 17.2 1.0 0.066 13.2 0.0 2.9 2 2 1 3 3 3 1 AAA ATPase domain TIP49 PF06068.8 KFX95314.1 - 0.0046 15.7 0.0 0.04 12.6 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus DUF815 PF05673.8 KFX95314.1 - 0.009 14.9 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ResIII PF04851.10 KFX95314.1 - 0.017 14.9 0.1 6.4 6.5 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_14 PF13173.1 KFX95314.1 - 0.02 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KFX95314.1 - 0.02 14.9 0.0 0.056 13.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.10 KFX95314.1 - 0.037 12.7 0.1 0.1 11.2 0.0 1.7 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 KFX95314.1 - 0.11 12.0 0.1 0.36 10.3 0.1 1.7 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.1 KFX95314.1 - 0.12 11.9 0.0 4.2 6.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Glyco_hydro_10 PF00331.15 KFX95315.1 - 4.9e-104 347.8 0.0 5.7e-104 347.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 G6PD_C PF02781.11 KFX95315.1 - 0.11 11.3 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, C-terminal domain DUF4339 PF14237.1 KFX95315.1 - 0.11 12.0 0.1 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) SPT2 PF08243.6 KFX95317.1 - 7.5e-08 32.6 10.5 7.5e-08 32.6 7.3 2.0 3 0 0 3 3 3 1 SPT2 chromatin protein SET PF00856.23 KFX95318.1 - 2.5e-08 34.3 0.2 6e-07 29.8 0.1 2.3 1 1 0 1 1 1 1 SET domain YukC PF10140.4 KFX95319.1 - 0.057 11.9 0.0 0.075 11.5 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC DUF3347 PF11827.3 KFX95319.1 - 0.062 13.2 0.1 0.074 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Chromo PF00385.19 KFX95320.1 - 0.0026 17.3 1.6 0.0065 16.1 1.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Proteasom_PSMB PF10508.4 KFX95320.1 - 0.039 12.2 0.1 4.8 5.3 0.0 2.2 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit STT3 PF02516.9 KFX95321.1 - 6.8e-133 444.1 39.6 5.5e-128 427.9 25.7 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit ATP-synt_E PF05680.7 KFX95321.1 - 2.9e-19 68.7 0.7 6.9e-19 67.5 0.1 1.9 2 0 0 2 2 2 1 ATP synthase E chain Cyclin PF08613.6 KFX95328.1 - 5.3e-14 52.8 0.0 7.2e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KFX95328.1 - 1.2e-06 28.1 0.0 1.8e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain PAH PF02671.16 KFX95328.1 - 0.018 14.6 0.0 0.03 13.9 0.0 1.4 1 0 0 1 1 1 0 Paired amphipathic helix repeat Fungal_trans PF04082.13 KFX95330.1 - 2.7e-10 39.5 0.0 4.1e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NB-ARC PF00931.17 KFX95331.1 - 1.9e-10 40.0 0.0 5.7e-10 38.5 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.1 KFX95331.1 - 1.1e-05 25.5 0.0 0.0032 17.4 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain TPR_12 PF13424.1 KFX95331.1 - 0.00036 20.4 4.2 0.0049 16.7 1.0 3.8 3 2 1 4 4 4 1 Tetratricopeptide repeat Arch_ATPase PF01637.13 KFX95331.1 - 0.0053 16.4 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase Apc3 PF12895.2 KFX95331.1 - 0.0085 16.2 0.4 0.31 11.1 0.1 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 AAA_22 PF13401.1 KFX95331.1 - 0.02 15.0 0.0 0.079 13.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFX95331.1 - 0.039 13.3 0.0 0.09 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_10 PF13374.1 KFX95331.1 - 0.049 13.5 0.4 0.75 9.8 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFX95331.1 - 0.13 12.7 0.4 34 5.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat EST1_DNA_bind PF10373.4 KFX95332.1 - 4.5e-12 45.7 0.0 7.3e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1_DNA_bind PF10373.4 KFX95339.1 - 2.5e-12 46.6 0.0 3.9e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain 14-3-3 PF00244.15 KFX95343.1 - 5.8e-10 38.6 0.1 2e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 14-3-3 protein WXG100 PF06013.7 KFX95344.1 - 2.2e-06 27.5 0.2 3e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Proteins of 100 residues with WXG DUF2388 PF09498.5 KFX95344.1 - 0.041 13.5 0.1 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) SseC PF04888.7 KFX95344.1 - 0.09 12.0 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Myb_DNA-bind_6 PF13921.1 KFX95345.1 - 0.00012 22.0 0.2 0.0006 19.8 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KFX95345.1 - 0.0074 16.3 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain FAM195 PF14799.1 KFX95345.1 - 0.078 12.8 1.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 FAM195 family DUF4096 PF13340.1 KFX95345.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Putative transposase of IS4/5 family (DUF4096) eIF-3c_N PF05470.7 KFX95345.1 - 9.2 4.2 11.2 13 3.7 7.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Ribosomal_L1 PF00687.16 KFX95346.1 - 8.2e-51 172.4 0.4 9.9e-51 172.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family RRM_1 PF00076.17 KFX95347.1 - 5.2e-58 192.5 1.3 5e-18 64.4 0.0 6.0 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX95347.1 - 7.9e-41 137.8 0.1 4.8e-12 45.6 0.0 5.8 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX95347.1 - 2.1e-25 88.3 3.5 1.9e-08 34.0 0.0 4.9 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SGT1 PF07093.6 KFX95347.1 - 0.011 14.1 11.8 0.02 13.2 8.2 1.4 1 0 0 1 1 1 0 SGT1 protein SET_assoc PF11767.3 KFX95347.1 - 0.016 14.4 0.0 4.6 6.6 0.0 3.2 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated Rox3 PF08633.5 KFX95348.1 - 9.8e-48 163.0 0.1 9.8e-48 163.0 0.1 2.1 2 0 0 2 2 2 1 Rox3 mediator complex subunit DUF2080 PF09853.4 KFX95348.1 - 0.075 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative transposon-encoded protein (DUF2080) Sas10 PF09368.5 KFX95349.1 - 9e-30 102.6 7.0 3.1e-29 100.9 4.9 2.0 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 KFX95349.1 - 1.9e-11 44.0 0.0 1.9e-11 44.0 0.0 3.6 4 0 0 4 4 4 1 Sas10/Utp3/C1D family adh_short PF00106.20 KFX95350.1 - 3.1e-18 66.2 0.1 4.5e-18 65.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX95350.1 - 1.2e-11 44.8 0.1 1.7e-11 44.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX95350.1 - 3.1e-07 30.2 0.1 4.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFX95350.1 - 0.0048 16.9 0.2 0.01 15.8 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KFX95350.1 - 0.014 15.2 0.3 0.03 14.0 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KFX95350.1 - 0.016 14.3 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 KFX95350.1 - 0.039 14.0 0.1 0.07 13.2 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 KFX95350.1 - 0.04 13.3 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 KFX95350.1 - 0.059 13.0 0.2 0.089 12.4 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ENOD93 PF03386.9 KFX95350.1 - 0.07 12.8 0.4 0.67 9.7 0.1 2.5 2 0 0 2 2 2 0 Early nodulin 93 ENOD93 protein DOPA_dioxygen PF08883.6 KFX95352.1 - 8.1e-31 106.1 0.0 1.5e-30 105.3 0.0 1.4 1 1 0 1 1 1 1 Dopa 4,5-dioxygenase family Cupin_8 PF13621.1 KFX95353.1 - 2.2e-25 89.5 0.0 2.8e-25 89.2 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 KFX95353.1 - 2.5e-05 23.7 0.1 5.5e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Cupin domain JmjC PF02373.17 KFX95353.1 - 4.1e-05 23.7 0.0 8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 KFX95353.1 - 0.00026 20.3 0.0 0.0007 18.9 0.0 1.6 1 0 0 1 1 1 1 Cupin superfamily protein AraC_binding PF02311.14 KFX95353.1 - 0.018 14.7 0.0 0.051 13.2 0.0 1.7 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_3 PF05899.7 KFX95353.1 - 0.03 13.7 0.0 0.076 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Pyr_redox_3 PF13738.1 KFX95354.1 - 1.6e-20 74.0 0.0 3e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFX95354.1 - 5.1e-10 38.1 0.2 3.5e-08 32.1 0.1 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KFX95354.1 - 3.5e-08 33.3 0.1 2.8e-07 30.4 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KFX95354.1 - 2.3e-07 30.0 0.0 5e-06 25.6 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 KFX95354.1 - 0.067 13.3 0.0 2 8.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase CK_II_beta PF01214.13 KFX95355.1 - 1.1e-76 256.4 0.0 2e-76 255.5 0.0 1.4 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 KFX95355.1 - 0.032 14.8 5.6 0.032 14.8 3.9 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PBP1_TM PF14812.1 KFX95355.1 - 0.26 11.6 10.1 1.3 9.4 3.0 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 KFX95355.1 - 4.3 6.8 9.5 0.59 9.6 3.4 1.7 2 0 0 2 2 2 0 Nucleoplasmin zf-H2C2_2 PF13465.1 KFX95356.1 - 6.6e-06 26.1 4.0 6.6e-06 26.1 2.8 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KFX95356.1 - 1.7e-05 24.8 11.1 0.0074 16.5 0.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX95356.1 - 2.5e-05 24.2 12.8 0.0034 17.5 1.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger Mito_carr PF00153.22 KFX95358.1 - 1.4e-36 124.0 0.2 3.9e-19 68.1 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein bZIP_1 PF00170.16 KFX95360.1 - 8.8e-09 35.1 10.4 1.3e-07 31.4 7.2 2.1 1 1 0 1 1 1 1 bZIP transcription factor PRTP PF01366.13 KFX95360.1 - 0.0096 13.9 0.4 0.013 13.5 0.2 1.1 1 0 0 1 1 1 1 Herpesvirus processing and transport protein DUF501 PF04417.7 KFX95360.1 - 0.3 10.9 3.3 0.092 12.5 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF501) bZIP_2 PF07716.10 KFX95360.1 - 0.43 10.4 9.6 5.1 7.0 6.7 2.2 1 1 0 1 1 1 0 Basic region leucine zipper Herpes_LMP2 PF07415.6 KFX95360.1 - 7.2 5.0 7.7 2 6.9 3.2 1.5 2 0 0 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein PrpF PF04303.8 KFX95361.1 - 5.9e-72 242.4 6.1 6.6e-72 242.3 4.3 1.0 1 0 0 1 1 1 1 PrpF protein ketoacyl-synt PF00109.21 KFX95363.1 - 4.2e-75 252.4 0.0 5.9e-75 252.0 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KFX95363.1 - 1.3e-30 105.6 0.0 3e-30 104.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 KFX95363.1 - 8.7e-05 21.6 0.0 0.00014 20.9 0.0 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_zinc_N PF00107.21 KFX95364.1 - 7.6e-08 31.9 0.0 1.3e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX95364.1 - 0.00014 21.5 0.3 0.00081 19.1 0.1 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 KFX95365.1 - 1.8e-40 138.8 0.0 2.2e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_5 PF12695.2 KFX95366.1 - 2e-07 30.8 0.2 3.3e-07 30.1 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 KFX95366.1 - 0.0003 19.7 0.0 0.00042 19.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 KFX95366.1 - 0.0068 15.3 0.0 0.009 14.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Dioxygenase_C PF00775.16 KFX95367.1 - 3.1e-50 169.9 0.0 4.4e-50 169.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KFX95367.1 - 5.1e-13 48.8 0.0 7.9e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KFX95367.1 - 0.0018 18.2 0.0 0.015 15.3 0.0 2.4 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF1684 PF07920.6 KFX95367.1 - 0.043 13.6 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1684) Lactonase PF10282.4 KFX95368.1 - 1.1e-15 57.5 0.0 1.6e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF4394 PF14339.1 KFX95368.1 - 0.1 11.8 0.1 1.1 8.5 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4394) OTT_1508_deam PF14441.1 KFX95371.1 - 3.6e-09 36.5 0.0 5.9e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 OTT_1508-like deaminase Epimerase PF01370.16 KFX95373.1 - 5.7e-16 58.6 0.0 8.6e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFX95373.1 - 3e-08 32.8 0.1 2.7e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 KFX95373.1 - 4.4e-06 25.6 0.0 1.5e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFX95373.1 - 1.2e-05 25.4 0.3 5.3e-05 23.2 0.2 2.1 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KFX95373.1 - 0.0029 17.3 0.8 0.06 13.0 0.0 2.2 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KFX95373.1 - 0.0038 17.1 2.4 0.74 9.7 0.0 2.7 3 0 0 3 3 3 2 short chain dehydrogenase NmrA PF05368.8 KFX95373.1 - 0.0072 15.6 0.0 0.02 14.1 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family PT-VENN PF04829.8 KFX95373.1 - 0.098 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif Polysacc_synt_2 PF02719.10 KFX95373.1 - 0.15 10.9 0.0 0.31 9.9 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SH3_3 PF08239.6 KFX95374.1 - 0.0012 19.0 0.0 0.0033 17.5 0.0 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain ABC_tran PF00005.22 KFX95375.1 - 2.8e-39 134.5 0.0 1.3e-18 67.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KFX95375.1 - 1.5e-27 96.7 25.1 4.9e-24 85.1 7.3 2.7 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KFX95375.1 - 5.7e-15 56.0 0.6 8.4e-06 25.9 0.1 4.4 2 2 1 3 3 3 2 AAA domain SMC_N PF02463.14 KFX95375.1 - 3.1e-10 39.6 1.6 0.032 13.4 0.0 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFX95375.1 - 3.7e-07 29.5 1.0 0.025 14.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KFX95375.1 - 6.8e-07 29.4 0.0 0.034 14.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KFX95375.1 - 7.3e-07 30.0 0.1 0.011 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 KFX95375.1 - 8e-07 28.2 0.0 0.00078 18.4 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 KFX95375.1 - 2.1e-06 27.8 0.3 0.0025 17.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KFX95375.1 - 1.3e-05 25.5 0.0 0.064 13.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KFX95375.1 - 1.7e-05 25.2 0.8 0.16 12.2 0.1 2.3 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KFX95375.1 - 1.7e-05 24.0 0.1 0.021 14.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFX95375.1 - 1.8e-05 24.2 0.4 0.14 11.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain Dynamin_N PF00350.18 KFX95375.1 - 9.5e-05 22.2 0.3 0.085 12.6 0.0 2.3 2 0 0 2 2 2 2 Dynamin family AAA_33 PF13671.1 KFX95375.1 - 0.00016 21.5 0.5 0.045 13.6 0.1 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KFX95375.1 - 0.00018 21.2 0.6 0.11 12.2 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KFX95375.1 - 0.0002 21.2 0.2 0.86 9.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 KFX95375.1 - 0.00028 21.3 0.1 0.072 13.5 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 KFX95375.1 - 0.00029 20.3 0.1 0.24 10.8 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_10 PF12846.2 KFX95375.1 - 0.00034 20.1 0.9 0.22 10.9 0.1 2.5 2 0 0 2 2 2 2 AAA-like domain DUF87 PF01935.12 KFX95375.1 - 0.0014 18.5 2.2 0.065 13.0 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 SbcCD_C PF13558.1 KFX95375.1 - 0.0016 18.3 4.1 0.25 11.2 0.3 3.5 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.24 KFX95375.1 - 0.0031 17.7 0.2 0.39 10.9 0.0 2.9 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KFX95375.1 - 0.0042 16.1 0.2 0.19 10.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 KFX95375.1 - 0.0088 15.7 0.4 0.13 12.0 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain Arch_ATPase PF01637.13 KFX95375.1 - 0.0091 15.7 0.0 0.45 10.1 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase Adeno_IVa2 PF02456.10 KFX95375.1 - 0.011 14.4 0.1 0.72 8.4 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein NACHT PF05729.7 KFX95375.1 - 0.012 15.2 0.1 3.6 7.2 0.0 2.7 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.12 KFX95375.1 - 0.014 14.9 0.2 0.12 11.9 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF815 PF05673.8 KFX95375.1 - 0.014 14.2 0.0 6.4 5.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 KFX95375.1 - 0.036 13.2 0.5 8.8 5.4 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KFX95375.1 - 0.046 13.9 0.1 4.3 7.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.12 KFX95375.1 - 0.049 13.0 0.0 34 3.7 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein Guanylate_kin PF00625.16 KFX95375.1 - 0.058 12.8 0.1 0.14 11.6 0.0 1.6 2 0 0 2 2 1 0 Guanylate kinase cobW PF02492.14 KFX95375.1 - 0.058 12.8 2.1 0.84 9.0 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KFX95375.1 - 0.088 12.2 0.6 0.84 9.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 KFX95375.1 - 0.16 11.4 0.5 18 4.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain FAD_binding_3 PF01494.14 KFX95376.1 - 1.7e-16 60.2 0.3 1.4e-14 53.9 0.3 2.8 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KFX95376.1 - 0.0038 17.2 0.0 0.018 15.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Ank_2 PF12796.2 KFX95377.1 - 4.8e-74 244.7 11.5 5.3e-13 49.1 0.1 10.1 4 2 7 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 KFX95377.1 - 1.7e-59 194.7 14.3 1.3e-05 24.7 0.2 17.0 18 0 0 18 18 18 13 Ankyrin repeat Ank_4 PF13637.1 KFX95377.1 - 6.4e-46 153.9 3.3 3.3e-09 37.0 0.0 11.8 9 6 1 10 10 10 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX95377.1 - 2e-44 145.1 7.5 0.0015 18.5 0.0 16.9 18 0 0 18 18 18 10 Ankyrin repeat Ank_5 PF13857.1 KFX95377.1 - 7.8e-34 114.9 7.3 0.00012 22.2 0.1 13.7 9 4 7 16 16 16 8 Ankyrin repeats (many copies) Clr5 PF14420.1 KFX95377.1 - 1.4e-15 56.9 0.3 2.7e-15 56.0 0.2 1.5 1 0 0 1 1 1 1 Clr5 domain Shigella_OspC PF06128.6 KFX95377.1 - 0.018 14.5 0.0 27 4.1 0.0 4.3 3 2 1 4 4 4 0 Shigella flexneri OspC protein TGS PF02824.16 KFX95377.1 - 0.089 12.6 0.0 0.27 11.1 0.0 1.8 1 0 0 1 1 1 0 TGS domain Fungal_trans PF04082.13 KFX95379.1 - 8.4e-22 77.2 1.5 1.7e-21 76.3 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KFX95379.1 - 0.00044 20.4 16.1 0.017 15.4 5.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX95379.1 - 0.027 14.7 14.5 0.31 11.4 4.4 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Sugar_tr PF00083.19 KFX95380.1 - 2.6e-83 280.0 31.0 3e-83 279.9 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX95380.1 - 1.2e-26 93.2 44.4 6.2e-26 90.9 18.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TauD PF02668.11 KFX95381.1 - 4.6e-38 131.3 0.0 5.9e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Peptidase_M35 PF02102.10 KFX95382.1 - 4.9e-92 308.3 18.5 5.8e-92 308.1 12.8 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family HRXXH PF13933.1 KFX95382.1 - 2.5e-07 30.3 1.9 7e-07 28.9 1.3 1.6 1 1 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.1 KFX95382.1 - 4.3e-05 24.0 0.5 7.4e-05 23.2 0.4 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase DUF1772 PF08592.6 KFX95384.1 - 7.6e-26 90.5 4.6 9.7e-26 90.1 3.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) TMEM237 PF15383.1 KFX95384.1 - 0.0099 15.0 0.4 0.014 14.5 0.3 1.1 1 0 0 1 1 1 1 Transmembrane protein 237 Erv26 PF04148.8 KFX95384.1 - 0.11 11.8 0.0 0.13 11.5 0.0 1.3 1 1 0 1 1 1 0 Transmembrane adaptor Erv26 Aldedh PF00171.17 KFX95385.1 - 2e-136 455.0 1.1 2.4e-136 454.7 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFX95385.1 - 0.0033 16.1 0.0 0.0074 15.0 0.0 1.5 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) Fungal_trans PF04082.13 KFX95388.1 - 2.3e-38 131.5 0.3 3.9e-38 130.8 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX95388.1 - 7.3e-05 22.5 13.6 0.00014 21.7 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.22 KFX95389.1 - 2.3e-42 144.5 2.1 1.7e-20 73.7 0.0 4.1 4 1 0 4 4 2 2 ABC transporter AAA_21 PF13304.1 KFX95389.1 - 9.8e-19 68.4 5.5 1.4e-06 28.4 0.8 4.3 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 KFX95389.1 - 3.2e-08 33.0 1.5 0.071 12.3 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain ABC_tran_2 PF12848.2 KFX95389.1 - 3.5e-07 29.9 2.3 3.5e-07 29.9 1.6 2.0 2 0 0 2 2 2 1 ABC transporter AAA_17 PF13207.1 KFX95389.1 - 5.8e-07 30.3 0.2 0.034 14.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KFX95389.1 - 8e-07 28.4 0.1 0.0012 18.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KFX95389.1 - 3.1e-06 27.3 0.8 0.36 10.9 0.0 3.8 3 1 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 KFX95389.1 - 4.6e-06 26.5 0.0 0.057 13.3 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 KFX95389.1 - 4.6e-05 23.7 0.5 0.26 11.6 0.5 3.0 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KFX95389.1 - 4.9e-05 22.9 0.0 0.45 10.0 0.0 3.8 3 1 0 3 3 3 1 AAA domain NACHT PF05729.7 KFX95389.1 - 0.00019 21.0 0.0 0.17 11.5 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 KFX95389.1 - 0.00029 20.8 2.7 0.82 9.6 0.0 3.5 4 0 0 4 4 3 2 AAA domain FtsK_SpoIIIE PF01580.13 KFX95389.1 - 0.00069 19.1 0.3 0.039 13.4 0.0 2.5 2 1 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.1 KFX95389.1 - 0.0012 19.2 12.5 0.029 14.7 1.5 3.4 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.1 KFX95389.1 - 0.0015 17.7 0.0 0.044 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.1 KFX95389.1 - 0.0015 18.5 6.2 0.96 9.4 0.1 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 KFX95389.1 - 0.0027 17.1 0.1 2.1 7.6 0.0 2.6 2 0 0 2 2 2 1 AAA-like domain DUF258 PF03193.11 KFX95389.1 - 0.0038 16.4 0.0 1.9 7.6 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Thymidylate_kin PF02223.12 KFX95389.1 - 0.0056 16.0 0.0 0.42 9.9 0.0 2.6 2 0 0 2 2 2 1 Thymidylate kinase cobW PF02492.14 KFX95389.1 - 0.0077 15.6 0.2 1.5 8.2 0.2 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 KFX95389.1 - 0.0079 15.6 0.8 0.25 10.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 KFX95389.1 - 0.014 15.9 0.0 8.6 6.8 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein MobB PF03205.9 KFX95389.1 - 0.014 15.0 0.0 4.3 7.0 0.0 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 KFX95389.1 - 0.015 14.9 0.1 6.1 6.5 0.0 3.1 3 0 0 3 3 3 0 NTPase Arf PF00025.16 KFX95389.1 - 0.023 13.9 0.1 2 7.6 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_33 PF13671.1 KFX95389.1 - 0.03 14.2 1.6 6.2 6.6 0.0 3.3 3 1 0 3 3 3 0 AAA domain SRP54 PF00448.17 KFX95389.1 - 0.033 13.6 0.0 1.9 7.8 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF87 PF01935.12 KFX95389.1 - 0.04 13.7 8.6 0.11 12.2 0.0 3.3 4 0 0 4 4 3 0 Domain of unknown function DUF87 G-alpha PF00503.15 KFX95389.1 - 0.06 12.0 0.2 0.12 11.0 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit AAA_5 PF07728.9 KFX95389.1 - 0.065 12.9 0.5 3.5 7.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.18 KFX95389.1 - 0.067 13.0 1.7 11 5.7 0.1 3.2 3 1 0 3 3 3 0 Dynamin family RNA_helicase PF00910.17 KFX95389.1 - 0.12 12.5 0.0 11 6.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_13 PF13166.1 KFX95389.1 - 0.13 10.6 3.4 4.1 5.7 0.0 3.2 3 1 0 3 3 3 0 AAA domain NB-ARC PF00931.17 KFX95389.1 - 0.36 9.6 2.6 12 4.6 0.0 3.2 4 0 0 4 4 4 0 NB-ARC domain Serglycin PF04360.7 KFX95390.1 - 0.006 16.3 1.7 0.027 14.1 1.0 2.1 2 0 0 2 2 2 1 Serglycin MFS_1 PF07690.11 KFX95391.1 - 8.5e-20 70.7 51.9 8.9e-17 60.8 19.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX95391.1 - 2.6e-05 22.7 35.1 0.0019 16.6 12.9 2.9 1 1 1 2 2 2 2 MFS/sugar transport protein DUF1228 PF06779.9 KFX95391.1 - 0.6 10.1 10.8 0.36 10.8 1.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) DUF2206 PF09971.4 KFX95391.1 - 1.6 7.4 3.8 0.94 8.2 1.0 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2206) Actin PF00022.14 KFX95396.1 - 7.5e-22 77.2 0.0 5.9e-19 67.7 0.0 3.0 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 KFX95396.1 - 0.029 12.9 0.1 0.54 8.7 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein DUF2114 PF09887.4 KFX95396.1 - 0.16 10.2 0.0 0.23 9.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Arf PF00025.16 KFX95397.1 - 1.4e-73 245.8 0.0 1.6e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFX95397.1 - 6.5e-13 48.2 0.0 8e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KFX95397.1 - 1.3e-10 40.9 0.0 1.5e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KFX95397.1 - 1.7e-10 40.1 1.4 1.1e-06 27.5 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KFX95397.1 - 4.3e-09 35.8 0.0 5.3e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KFX95397.1 - 4.2e-08 33.7 0.0 6e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFX95397.1 - 2.6e-06 27.3 0.0 3.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFX95397.1 - 4.7e-05 22.9 0.0 0.0067 15.8 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KFX95397.1 - 0.012 14.9 0.6 0.047 12.9 0.4 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF3986 PF13143.1 KFX95397.1 - 0.12 12.8 0.2 0.26 11.7 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Paf1 PF03985.8 KFX95398.1 - 3.1e-46 158.0 0.3 2.1e-45 155.3 0.2 1.9 1 1 0 1 1 1 1 Paf1 Rer1 PF03248.8 KFX95399.1 - 3e-81 271.2 1.9 3.4e-81 271.0 1.3 1.0 1 0 0 1 1 1 1 Rer1 family FlgM PF04316.8 KFX95400.1 - 0.00063 19.6 0.9 0.0031 17.4 0.2 2.4 2 0 0 2 2 2 1 Anti-sigma-28 factor, FlgM Prefoldin_2 PF01920.15 KFX95400.1 - 0.094 12.4 1.7 2.7 7.7 0.2 2.7 2 0 0 2 2 2 0 Prefoldin subunit IMS_C PF11799.3 KFX95401.1 - 0.12 12.3 0.1 14 5.6 0.0 2.6 2 1 0 2 2 2 0 impB/mucB/samB family C-terminal domain DUF3505 PF12013.3 KFX95402.1 - 1.6e-21 76.5 2.3 6.5e-10 39.2 0.8 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF3505) zf-C2H2_2 PF12756.2 KFX95402.1 - 0.027 14.5 5.9 0.12 12.5 0.1 3.4 3 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Ebp2 PF05890.7 KFX95404.1 - 2e-21 76.5 0.6 2e-21 76.5 0.4 2.1 2 0 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 BUD22 PF09073.5 KFX95404.1 - 0.016 14.2 13.7 0.016 14.2 9.5 1.1 1 0 0 1 1 1 0 BUD22 Glyco_hydro_3_C PF01915.17 KFX95404.1 - 0.092 12.2 1.6 0.15 11.5 1.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Nop14 PF04147.7 KFX95404.1 - 7.5 4.3 18.9 9.2 4.0 13.1 1.2 1 0 0 1 1 1 0 Nop14-like family Pmp3 PF01679.12 KFX95428.1 - 2.3e-18 65.5 8.0 3.6e-18 64.9 5.5 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Glycogen_syn PF05693.8 KFX95429.1 - 0 1106.6 0.0 4.1e-177 590.2 0.0 2.0 2 0 0 2 2 2 2 Glycogen synthase Glycos_transf_1 PF00534.15 KFX95429.1 - 6.5e-06 25.6 0.0 0.0013 18.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 KFX95429.1 - 1.1e-05 25.1 0.0 2.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 KFX95429.1 - 1.6e-05 25.1 1.6 2.7e-05 24.3 0.1 2.3 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Aminotran_1_2 PF00155.16 KFX95430.1 - 8.8e-81 271.6 0.0 1.1e-80 271.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KFX95430.1 - 2.5e-06 26.4 0.1 3.4e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KFX95430.1 - 0.00071 17.9 0.0 0.0012 17.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 KFX95430.1 - 0.0079 15.3 0.5 0.015 14.4 0.4 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase GFA PF04828.9 KFX95431.1 - 0.0019 18.1 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Peptidase_M20 PF01546.23 KFX95432.1 - 2.3e-06 27.2 0.0 3.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFX95432.1 - 1.8e-05 24.4 0.2 0.00017 21.3 0.1 2.3 2 1 0 2 2 2 1 Peptidase dimerisation domain Ribosomal_L28e PF01778.12 KFX95436.1 - 3.2e-22 79.1 0.4 3.4e-22 79.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family Sec1 PF00995.18 KFX95443.1 - 1.2e-59 202.4 0.0 1.4e-59 202.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Amino_oxidase PF01593.19 KFX95444.1 - 3.8e-85 286.6 0.0 6.9e-85 285.7 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase HMG_box PF00505.14 KFX95444.1 - 9.1e-09 35.4 0.7 2e-08 34.3 0.1 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box SWIRM PF04433.12 KFX95444.1 - 2.3e-07 30.8 0.0 5.3e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 KFX95444.1 - 7.3e-07 29.1 0.2 2.2e-06 27.5 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box_2 PF09011.5 KFX95444.1 - 2.8e-06 27.5 0.2 5.6e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain DUF2057 PF09829.4 KFX95444.1 - 0.054 13.1 0.0 0.37 10.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) ADH_N PF08240.7 KFX95453.1 - 7.6e-27 93.2 1.8 1.1e-26 92.7 0.4 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX95453.1 - 1.7e-16 59.9 0.2 4e-12 45.8 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 KFX95453.1 - 0.0082 16.2 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 KFX95453.1 - 0.069 12.5 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF1253 PF06862.7 KFX95453.1 - 0.2 10.0 0.0 0.28 9.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) Ank_2 PF12796.2 KFX95454.1 - 1.7e-127 416.0 48.7 1.1e-19 70.5 0.2 7.4 3 1 4 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 KFX95454.1 - 8.4e-86 277.8 44.1 2.2e-08 33.4 0.1 15.8 14 1 1 15 15 15 14 Ankyrin repeat Ank_4 PF13637.1 KFX95454.1 - 5.4e-62 205.1 23.0 7.7e-09 35.8 0.2 12.3 4 4 9 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX95454.1 - 5.3e-55 177.8 27.8 0.0018 18.2 0.0 16.4 16 0 0 16 16 16 13 Ankyrin repeat Ank_5 PF13857.1 KFX95454.1 - 1.7e-45 152.0 34.5 2.2e-07 30.9 0.2 12.2 2 1 10 14 14 14 12 Ankyrin repeats (many copies) NACHT PF05729.7 KFX95454.1 - 1.2e-06 28.2 0.1 4e-06 26.5 0.0 1.9 1 1 1 2 2 2 1 NACHT domain GATase PF00117.23 KFX95455.1 - 1.3e-45 155.2 0.0 1.9e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 KFX95455.1 - 2.8e-45 153.0 0.0 5.2e-45 152.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Leader_CPA1 PF08252.6 KFX95455.1 - 6.8e-14 50.7 0.3 1.4e-13 49.7 0.2 1.5 1 0 0 1 1 1 1 arg-2/CPA1 leader peptide Peptidase_C26 PF07722.8 KFX95455.1 - 3.4e-07 29.9 0.1 1.2e-05 24.8 0.0 2.3 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 KFX95455.1 - 0.058 12.8 0.1 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Dak1_2 PF13684.1 KFX95456.1 - 0.0046 15.9 1.3 0.0054 15.7 0.9 1.0 1 0 0 1 1 1 1 Dihydroxyacetone kinase family Ank_2 PF12796.2 KFX95474.1 - 1.9e-34 117.8 7.1 2.8e-10 40.3 0.3 4.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFX95474.1 - 1.7e-18 65.3 12.8 0.00036 20.2 0.0 8.9 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.1 KFX95474.1 - 6.4e-15 54.8 6.6 0.001 19.2 0.0 6.8 4 3 3 7 7 7 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFX95474.1 - 8e-15 54.8 4.4 1.2e-05 25.7 0.0 7.4 5 1 4 9 9 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX95474.1 - 4.1e-14 51.2 8.8 0.0027 17.7 0.0 8.5 9 0 0 9 9 9 4 Ankyrin repeat AAA_16 PF13191.1 KFX95474.1 - 9.9e-07 28.9 0.0 5.6e-06 26.4 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain NACHT PF05729.7 KFX95474.1 - 1.8e-06 27.6 0.0 3.9e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KFX95474.1 - 8.4e-05 22.7 0.0 0.0003 20.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain Shigella_OspC PF06128.6 KFX95474.1 - 0.091 12.2 0.0 2.3 7.6 0.0 2.4 1 1 0 2 2 2 0 Shigella flexneri OspC protein AAA PF00004.24 KFX95474.1 - 0.22 11.7 1.2 0.68 10.1 0.2 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Trehalase PF01204.13 KFX95476.1 - 3.8e-188 626.2 0.0 5e-188 625.9 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 KFX95476.1 - 1.6e-17 62.5 1.3 3e-17 61.6 0.9 1.5 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain RHH_4 PF13467.1 KFX95476.1 - 0.07 13.0 0.0 5.1 7.0 0.0 2.6 2 0 0 2 2 2 0 Ribbon-helix-helix domain Mad3_BUB1_I PF08311.7 KFX95491.1 - 3.8e-41 139.8 0.0 8.3e-41 138.7 0.0 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 KFX95491.1 - 2.5e-11 43.2 0.0 5.1e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX95491.1 - 0.0022 17.1 0.1 0.011 14.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFX95491.1 - 0.017 14.8 0.1 0.017 14.8 0.0 2.6 3 0 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 KFX95491.1 - 0.074 12.1 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PI3K_1B_p101 PF10486.4 KFX95491.1 - 1.2 6.6 9.1 0.68 7.4 4.8 1.6 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Indigoidine_A PF04227.7 KFX95492.1 - 7e-115 383.2 0.5 1.1e-114 382.6 0.4 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 KFX95492.1 - 4.9e-14 52.1 5.0 2e-07 30.4 0.0 3.0 3 0 0 3 3 3 2 pfkB family carbohydrate kinase RabGAP-TBC PF00566.13 KFX95512.1 - 3.3e-47 160.7 0.0 5.9e-47 159.9 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain ATP-synt_E PF05680.7 KFX95515.1 - 0.056 13.4 5.2 0.051 13.5 0.9 2.7 2 1 0 3 3 3 0 ATP synthase E chain GTP_EFTU PF00009.22 KFX95516.1 - 6.9e-09 35.3 0.0 2.5e-08 33.5 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KFX95516.1 - 0.19 10.9 0.0 0.4 9.8 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Rab5ip PF07019.7 KFX95517.1 - 1.6e-21 76.2 5.0 2e-21 75.8 3.4 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF3611 PF12263.3 KFX95517.1 - 0.049 13.0 0.4 0.056 12.8 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3611) BCLP PF12304.3 KFX95517.1 - 0.15 11.4 1.3 2.4 7.5 0.1 2.1 1 1 1 2 2 2 0 Beta-casein like protein Nro1 PF12753.2 KFX95518.1 - 0.061 12.2 0.0 0.093 11.6 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 PCNA_N PF00705.13 KFX95519.1 - 1.9e-54 182.5 3.9 4.5e-54 181.3 2.7 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Vezatin PF12632.2 KFX95519.1 - 2.9e-52 177.2 0.4 4.9e-52 176.5 0.0 1.6 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes PCNA_C PF02747.10 KFX95519.1 - 4.5e-49 165.6 0.0 9.5e-49 164.5 0.0 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 KFX95519.1 - 4.9e-09 35.6 0.0 8.9e-09 34.8 0.0 1.4 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.7 KFX95519.1 - 0.0014 17.6 0.1 0.0031 16.5 0.1 1.6 1 1 0 1 1 1 1 Hus1-like protein DUF1480 PF07351.8 KFX95519.1 - 0.086 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1480) Amastin PF07344.6 KFX95519.1 - 0.12 11.9 0.6 0.25 10.9 0.4 1.4 1 0 0 1 1 1 0 Amastin surface glycoprotein Spore_permease PF03845.8 KFX95519.1 - 0.45 9.1 0.5 0.7 8.4 0.4 1.1 1 0 0 1 1 1 0 Spore germination protein Phos_pyr_kin PF08543.7 KFX95520.1 - 6.3e-14 51.7 0.0 1.4e-13 50.6 0.0 1.6 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 KFX95520.1 - 4.8e-09 35.7 0.5 1.3e-06 27.8 0.0 2.3 2 1 0 2 2 2 2 pfkB family carbohydrate kinase dUTPase PF00692.14 KFX95521.1 - 1.4e-42 144.1 0.0 1.8e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 dUTPase DCD PF06559.6 KFX95521.1 - 0.033 12.5 0.0 0.043 12.1 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) MARVEL PF01284.18 KFX95522.1 - 1.8e-06 27.8 19.5 2.4e-06 27.4 13.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain Init_tRNA_PT PF04179.7 KFX95523.1 - 5e-157 523.3 0.0 5.9e-157 523.1 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Serglycin PF04360.7 KFX95524.1 - 0.017 14.8 0.2 0.03 14.0 0.1 1.5 1 1 0 1 1 1 0 Serglycin MF_alpha_N PF05436.6 KFX95524.1 - 0.033 13.8 0.5 0.089 12.4 0.3 1.8 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus AF-4 PF05110.8 KFX95524.1 - 1 7.1 7.7 0.98 7.2 5.3 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Fer4_3 PF12798.2 KFX95524.1 - 6.2 7.6 9.3 2.5 8.8 0.1 3.1 2 1 1 3 3 3 0 4Fe-4S binding domain Aldolase_II PF00596.16 KFX95525.1 - 2e-41 141.6 0.0 2.4e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Calreticulin PF00262.13 KFX95526.1 - 3.1e-160 532.8 18.5 3.1e-160 532.8 12.8 1.4 2 0 0 2 2 2 1 Calreticulin family Mito_carr PF00153.22 KFX95529.1 - 2.1e-20 72.2 0.3 2.3e-20 72.0 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein zf-H2C2 PF09337.5 KFX95541.1 - 5.4e-21 73.7 4.0 8.7e-21 73.0 2.8 1.3 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 KFX95541.1 - 0.00037 20.4 0.0 0.00095 19.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KFX95541.1 - 0.011 15.7 0.0 0.03 14.2 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KFX95541.1 - 0.02 15.0 0.0 0.044 13.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFX95541.1 - 0.04 13.6 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Imm47 PF15586.1 KFX95541.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 47 Cpn60_TCP1 PF00118.19 KFX95542.1 - 1.3e-140 469.2 5.2 1.7e-140 468.8 3.6 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PCI_Csn8 PF10075.4 KFX95542.1 - 5.8e-39 133.1 0.0 1e-38 132.3 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KFX95542.1 - 1.6e-24 86.6 0.0 2.6e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family HD PF01966.17 KFX95543.1 - 5.7e-09 36.0 0.1 7.8e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 HD domain HD_4 PF13328.1 KFX95543.1 - 0.00075 19.2 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 HD domain DUF706 PF05153.10 KFX95543.1 - 0.0082 15.4 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF706) HDOD PF08668.7 KFX95543.1 - 0.0097 15.1 0.0 0.025 13.8 0.0 1.6 1 1 0 1 1 1 1 HDOD domain Hydrolase_6 PF13344.1 KFX95543.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase PhyH PF05721.8 KFX95544.1 - 9.4e-26 91.1 0.0 1.2e-25 90.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.1 KFX95544.1 - 0.00034 21.0 0.0 0.00076 19.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.1 KFX95544.1 - 0.0013 19.0 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase Sugar_tr PF00083.19 KFX95545.1 - 2.7e-41 141.6 31.5 1.9e-39 135.4 20.5 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX95545.1 - 1.2e-32 113.0 53.5 5.4e-22 77.9 23.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DNA_ligase_A_M PF01068.16 KFX95546.1 - 9.7e-50 168.7 0.1 5.3e-47 159.8 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KFX95546.1 - 4.6e-42 143.8 0.1 1.2e-41 142.5 0.0 1.8 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KFX95546.1 - 1.9e-17 63.4 0.0 9.1e-17 61.2 0.0 2.2 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RINT1_TIP1 PF04437.8 KFX95547.1 - 1.1e-95 321.1 0.0 1.6e-95 320.5 0.0 1.2 1 0 0 1 1 1 1 RINT-1 / TIP-1 family SR-25 PF10500.4 KFX95548.1 - 1.1 8.6 9.8 1.6 8.1 6.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ketoacyl-synt PF00109.21 KFX95549.1 - 3.7e-82 275.6 0.5 6.3e-82 274.8 0.0 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KFX95549.1 - 3.5e-38 130.0 0.1 1.4e-37 128.2 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 KFX95549.1 - 9.5e-29 100.7 0.2 1.4e-28 100.1 0.1 1.2 1 0 0 1 1 1 1 Acyl transferase domain Thiolase_N PF00108.18 KFX95549.1 - 4.6e-05 22.5 0.1 8.3e-05 21.6 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain RF-1 PF00472.15 KFX95569.1 - 1.2e-24 86.2 0.3 1.7e-24 85.8 0.2 1.1 1 0 0 1 1 1 1 RF-1 domain Cwf_Cwc_15 PF04889.7 KFX95569.1 - 0.017 14.8 0.5 0.022 14.4 0.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GCS PF03074.11 KFX95571.1 - 8.8e-152 505.4 0.0 1.2e-151 505.0 0.0 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase ADH_zinc_N PF00107.21 KFX95576.1 - 2.2e-28 98.3 0.9 3.8e-28 97.6 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX95576.1 - 8.8e-14 52.4 0.1 2.5e-13 51.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX95576.1 - 5e-11 42.3 0.0 1.2e-10 41.0 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 KFX95576.1 - 0.00031 20.7 0.0 0.00056 19.9 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 KFX95576.1 - 0.077 12.5 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_hydro_61 PF03443.9 KFX95577.1 - 2.4e-57 194.2 0.0 3.1e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Metallophos PF00149.23 KFX95579.1 - 1.4e-34 119.2 0.3 7.9e-29 100.4 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Pyridox_oxase_2 PF12766.2 KFX95581.1 - 1.4e-21 76.6 0.0 2.5e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Fungal_trans PF04082.13 KFX95582.1 - 1.1e-43 148.9 0.1 2.5e-43 147.8 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX95582.1 - 1.1e-08 34.8 8.1 2.2e-08 33.8 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cellulase PF00150.13 KFX95583.1 - 1e-28 100.3 0.8 1.5e-28 99.8 0.5 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) INCENP_N PF12178.3 KFX95583.1 - 0.014 14.9 0.0 0.031 13.8 0.0 1.6 1 0 0 1 1 1 0 Chromosome passenger complex (CPC) protein INCENP N terminal Nipped-B_C PF12830.2 KFX95584.1 - 3.1e-45 154.1 7.4 3.3e-45 154.0 1.9 3.2 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 KFX95584.1 - 1.2e-08 34.7 2.3 2.8e-08 33.5 0.3 2.7 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 KFX95584.1 - 0.11 12.6 6.5 16 5.8 0.0 5.4 5 0 0 5 5 5 0 HEAT repeat TFIIS_C PF01096.13 KFX95585.1 - 4e-14 51.9 1.9 4e-14 51.9 1.3 3.2 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KFX95585.1 - 9e-05 22.0 2.5 9e-05 22.0 1.8 2.5 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit zinc_ribbon_2 PF13240.1 KFX95585.1 - 0.00065 19.0 9.7 1.9 8.0 0.0 4.1 4 0 0 4 4 4 2 zinc-ribbon domain IBR PF01485.16 KFX95585.1 - 0.042 13.7 9.0 0.19 11.6 0.4 2.4 2 1 0 2 2 2 0 IBR domain RecR PF02132.10 KFX95585.1 - 0.068 12.6 5.6 0.087 12.2 1.7 2.3 2 0 0 2 2 2 0 RecR protein Ogr_Delta PF04606.7 KFX95585.1 - 0.094 12.3 0.6 0.094 12.3 0.4 2.8 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger DUF2072 PF09845.4 KFX95585.1 - 0.12 12.2 5.8 1.5 8.7 1.0 2.2 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) zf-ribbon_3 PF13248.1 KFX95585.1 - 0.17 11.1 0.2 0.17 11.1 0.1 3.7 3 1 1 4 4 4 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 KFX95585.1 - 0.18 11.4 13.4 0.97 9.1 1.5 2.9 2 2 0 2 2 2 0 Putative transposase DNA-binding domain Mu-like_Com PF10122.4 KFX95585.1 - 0.21 10.6 2.7 1.4 7.9 0.6 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com Lar_restr_allev PF14354.1 KFX95585.1 - 0.25 11.6 10.6 0.89 9.9 0.4 3.1 2 1 1 3 3 3 0 Restriction alleviation protein Lar DUF164 PF02591.10 KFX95585.1 - 0.26 11.1 4.4 2 8.3 0.1 2.9 3 0 0 3 3 3 0 Putative zinc ribbon domain RRN7 PF11781.3 KFX95585.1 - 0.34 10.4 12.3 0.76 9.3 0.3 3.9 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 KFX95585.1 - 0.43 10.4 14.0 3.3 7.5 6.1 2.9 1 1 0 2 2 2 0 Double zinc ribbon Ribosomal_S27e PF01667.12 KFX95585.1 - 0.66 9.5 7.3 14 5.2 0.0 3.2 2 1 1 3 3 3 0 Ribosomal protein S27 Zn-ribbon_8 PF09723.5 KFX95585.1 - 0.71 9.8 0.1 0.71 9.8 0.1 3.2 3 1 0 3 3 3 0 Zinc ribbon domain HypA PF01155.14 KFX95585.1 - 1.1 8.9 9.0 3.2 7.4 0.7 2.4 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family UPF0547 PF10571.4 KFX95585.1 - 1.1 9.0 0.0 1.1 9.0 0.0 3.8 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-IS66 PF13005.2 KFX95585.1 - 2.2 8.3 11.2 15 5.6 0.3 3.9 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 zf-ISL3 PF14690.1 KFX95585.1 - 4.4 7.4 6.1 8.6 6.4 0.0 3.2 4 0 0 4 4 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 TF_Zn_Ribbon PF08271.7 KFX95585.1 - 4.5 6.6 18.4 1.3 8.3 0.2 3.7 2 2 1 3 3 3 0 TFIIB zinc-binding Zn_ribbon_recom PF13408.1 KFX95585.1 - 7.6 6.8 13.3 12 6.2 0.1 3.3 2 2 1 3 3 3 0 Recombinase zinc beta ribbon domain zf-RING_3 PF14369.1 KFX95585.1 - 9.5 6.3 7.5 1.4 8.9 0.1 2.6 2 1 0 2 2 2 0 zinc-finger HEAT_2 PF13646.1 KFX95586.1 - 4.7e-29 100.5 9.5 3.5e-16 59.2 0.2 3.3 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.11 KFX95586.1 - 3.6e-19 67.2 7.0 0.00075 19.7 0.1 6.6 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 KFX95586.1 - 8.3e-07 29.3 10.7 0.0021 18.4 0.4 4.8 2 2 2 4 4 4 3 HEAT-like repeat HEAT PF02985.17 KFX95586.1 - 4.9e-06 26.1 6.6 0.086 12.9 0.0 5.6 6 0 0 6 6 6 2 HEAT repeat HrpB1_HrpK PF09613.5 KFX95586.1 - 0.013 14.9 3.5 0.032 13.7 0.8 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) Cohesin_HEAT PF12765.2 KFX95586.1 - 0.048 13.6 0.8 0.75 9.8 0.0 3.0 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion ABC_tran PF00005.22 KFX95587.1 - 1.3e-47 161.5 0.1 2.9e-23 82.7 0.0 3.8 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFX95587.1 - 4.2e-18 65.3 0.0 5e-06 25.8 0.0 3.8 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFX95587.1 - 1.1e-17 65.0 0.5 0.00063 19.8 0.0 4.3 3 1 0 4 4 4 4 AAA domain AAA_29 PF13555.1 KFX95587.1 - 1.4e-09 37.3 0.1 0.0013 18.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KFX95587.1 - 2.5e-08 34.4 6.6 0.0011 19.3 0.9 3.3 3 1 0 3 3 2 2 AAA domain AAA_17 PF13207.1 KFX95587.1 - 2.5e-08 34.7 0.0 0.0031 18.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KFX95587.1 - 3.1e-08 32.9 0.1 0.00026 20.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KFX95587.1 - 7.1e-08 32.6 0.1 0.00065 19.8 0.0 3.5 4 0 0 4 4 2 2 AAA domain MMR_HSR1 PF01926.18 KFX95587.1 - 1.3e-07 31.5 0.0 0.0027 17.6 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_15 PF13175.1 KFX95587.1 - 1.7e-07 30.6 0.9 0.22 10.5 0.0 4.0 3 1 1 4 4 4 3 AAA ATPase domain Dynamin_N PF00350.18 KFX95587.1 - 4.8e-07 29.7 0.1 0.00041 20.2 0.0 3.0 3 0 0 3 3 2 1 Dynamin family AAA_28 PF13521.1 KFX95587.1 - 4.9e-07 29.8 0.1 0.0087 16.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KFX95587.1 - 2e-06 27.7 0.1 0.089 12.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 KFX95587.1 - 6.2e-06 25.8 0.1 0.26 10.7 0.0 3.5 3 0 0 3 3 3 2 AAA-like domain Miro PF08477.8 KFX95587.1 - 1.1e-05 25.9 0.1 0.062 13.8 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_18 PF13238.1 KFX95587.1 - 1.3e-05 25.4 0.2 0.27 11.5 0.0 3.5 3 0 0 3 3 2 2 AAA domain MobB PF03205.9 KFX95587.1 - 1.5e-05 24.6 0.0 0.22 11.2 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 KFX95587.1 - 3.1e-05 22.8 0.1 0.2 10.3 0.0 2.5 2 0 0 2 2 2 2 ArgK protein SbcCD_C PF13558.1 KFX95587.1 - 3.5e-05 23.6 0.0 0.14 12.1 0.0 3.0 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 KFX95587.1 - 4.9e-05 23.4 0.0 0.7 10.1 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA PF00004.24 KFX95587.1 - 6.3e-05 23.1 0.0 0.36 11.0 0.0 4.0 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFX95587.1 - 0.00013 21.9 0.3 1.1 9.2 0.0 4.0 4 0 0 4 4 4 1 AAA ATPase domain NACHT PF05729.7 KFX95587.1 - 0.00023 20.8 0.1 0.088 12.4 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 KFX95587.1 - 0.00025 20.8 0.1 0.7 9.5 0.0 3.2 3 0 0 3 3 2 2 Archaeal ATPase AAA_14 PF13173.1 KFX95587.1 - 0.00036 20.4 0.0 0.9 9.4 0.0 3.4 3 1 0 3 3 3 1 AAA domain PduV-EutP PF10662.4 KFX95587.1 - 0.00055 19.4 0.0 0.88 9.0 0.0 3.2 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 KFX95587.1 - 0.0017 17.8 0.7 1.2 8.5 0.0 3.3 4 0 0 4 4 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 KFX95587.1 - 0.0023 17.8 2.0 1 9.1 0.0 3.6 3 0 0 3 3 3 1 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 KFX95587.1 - 0.0038 16.7 0.0 3 7.2 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 KFX95587.1 - 0.0045 16.6 0.0 5.5 6.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain MutS_V PF00488.16 KFX95587.1 - 0.0049 16.2 0.0 0.73 9.1 0.0 2.4 2 0 0 2 2 2 1 MutS domain V AAA_25 PF13481.1 KFX95587.1 - 0.0077 15.6 0.0 6.1 6.2 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 KFX95587.1 - 0.0097 14.4 12.5 0.87 7.9 0.0 4.6 4 1 0 5 5 5 1 AAA domain ATP_bind_1 PF03029.12 KFX95587.1 - 0.024 14.1 0.1 7.6 5.9 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 KFX95587.1 - 0.026 14.0 0.1 3.1 7.2 0.0 2.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Septin PF00735.13 KFX95587.1 - 0.028 13.4 0.2 2.9 6.8 0.0 2.7 3 0 0 3 3 2 0 Septin Mg_chelatase PF01078.16 KFX95587.1 - 0.03 13.4 0.0 2.9 6.9 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI PRK PF00485.13 KFX95587.1 - 0.034 13.7 0.0 1.5 8.3 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.10 KFX95587.1 - 0.038 12.6 0.0 3.9 6.0 0.0 2.3 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein HEAT PF02985.17 KFX95587.1 - 0.054 13.5 0.6 8.7 6.7 0.0 3.8 4 0 0 4 4 2 0 HEAT repeat NTPase_1 PF03266.10 KFX95587.1 - 0.06 13.0 0.0 16 5.1 0.0 2.8 2 0 0 2 2 2 0 NTPase T2SE PF00437.15 KFX95587.1 - 0.06 12.2 2.3 4.9 5.9 0.0 3.4 3 0 0 3 3 3 0 Type II/IV secretion system protein NB-ARC PF00931.17 KFX95587.1 - 0.084 11.7 1.5 0.4 9.5 0.0 2.4 3 0 0 3 3 2 0 NB-ARC domain V-ATPase_H_C PF11698.3 KFX95587.1 - 0.089 12.7 1.7 0.26 11.2 1.2 1.8 1 0 0 1 1 1 0 V-ATPase subunit H DAP3 PF10236.4 KFX95587.1 - 1.5 7.6 6.7 11 4.8 0.8 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Nol1_Nop2_Fmu PF01189.12 KFX95603.1 - 3.3e-30 105.4 0.0 2.1e-23 83.1 0.0 3.3 2 1 1 3 3 3 3 NOL1/NOP2/sun family F-box-like PF12937.2 KFX95603.1 - 3.1e-06 26.8 0.0 8.8e-06 25.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX95603.1 - 5.8e-06 25.8 0.0 1.3e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 KFX95603.1 - 0.0058 16.3 0.1 0.033 13.9 0.0 2.2 3 0 0 3 3 3 1 F-box-like domain Transglut_core PF01841.14 KFX95604.1 - 3.8e-11 43.1 0.0 7.5e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 KFX95604.1 - 0.002 17.3 0.0 0.018 14.3 0.0 2.3 2 1 0 2 2 2 1 Transglutaminase-like domain Hemerythrin PF01814.18 KFX95605.1 - 2.1e-08 34.3 1.0 3.7e-08 33.6 0.7 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Aldolase_II PF00596.16 KFX95606.1 - 4.3e-44 150.3 0.1 6.1e-44 149.8 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SET PF00856.23 KFX95610.1 - 1.8e-06 28.3 0.0 8.3e-06 26.2 0.0 2.0 1 1 0 1 1 1 1 SET domain F-box-like PF12937.2 KFX95611.1 - 1.2e-06 28.1 1.1 1.2e-06 28.1 0.8 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KFX95611.1 - 0.001 18.6 0.1 0.0045 16.6 0.1 2.2 1 0 0 1 1 1 1 F-box domain COesterase PF00135.23 KFX95612.1 - 3.3e-88 296.7 0.0 4.3e-88 296.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX95612.1 - 9e-07 28.6 0.1 2.6e-06 27.1 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX95612.1 - 0.034 13.8 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2424 PF10340.4 KFX95612.1 - 0.12 11.0 0.2 0.28 9.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Aconitase PF00330.15 KFX95613.1 - 8.9e-65 218.9 0.0 1.6e-40 138.9 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KFX95613.1 - 4.7e-23 81.7 0.0 8.8e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain GST_C_4 PF14834.1 KFX95613.1 - 0.13 12.2 0.0 25 4.8 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Erf4 PF10256.4 KFX95615.1 - 5.5e-05 23.0 0.0 6.5e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Thioredox_DsbH PF03190.10 KFX95617.1 - 5.5e-67 224.5 0.0 9e-67 223.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 KFX95617.1 - 3e-10 39.9 0.0 6.5e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KFX95617.1 - 0.00031 20.9 0.0 0.00068 19.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like domain HTH_10 PF04967.7 KFX95617.1 - 0.14 11.7 0.1 0.32 10.6 0.1 1.6 1 0 0 1 1 1 0 HTH DNA binding domain DUF2406 PF10295.4 KFX95621.1 - 7.6e-21 74.3 0.6 7.6e-21 74.3 0.4 2.4 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) VMA21 PF09446.5 KFX95622.1 - 9.6e-15 54.2 10.4 1.5e-14 53.6 7.2 1.3 1 0 0 1 1 1 1 VMA21-like domain SNF2_N PF00176.18 KFX95623.1 - 8.5e-57 192.2 0.0 1.3e-56 191.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFX95623.1 - 7.5e-13 48.1 0.1 3.6e-12 45.9 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX95623.1 - 0.00061 19.6 0.0 0.0017 18.2 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KFX95623.1 - 0.019 13.8 0.2 0.11 11.3 0.1 2.1 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 TK PF00265.13 KFX95623.1 - 0.068 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Thymidine kinase G6PD_C PF02781.11 KFX95641.1 - 8.4e-135 448.2 0.0 1.5e-134 447.4 0.0 1.4 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KFX95641.1 - 5e-66 222.4 0.2 8.7e-66 221.6 0.1 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3226 PF11536.3 KFX95641.1 - 0.0066 15.9 0.1 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3226) Ribosomal_L35Ae PF01247.13 KFX95642.1 - 1e-42 143.7 0.7 1.2e-42 143.5 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 KFX95642.1 - 0.0093 15.8 0.0 2.5 8.0 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF3425 PF11905.3 KFX95660.1 - 0.00026 20.9 0.0 0.00039 20.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) PGAP1 PF07819.8 KFX95661.1 - 0.00038 20.1 0.2 0.00059 19.4 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KFX95661.1 - 0.0028 17.4 4.1 0.0038 16.9 2.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX95661.1 - 0.013 15.4 9.1 0.037 13.9 6.3 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 KFX95661.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.20 KFX95661.1 - 0.11 12.0 0.1 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF1025 PF06262.6 KFX95663.1 - 0.029 14.1 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase DUF4396 PF14342.1 KFX95664.1 - 1.1e-29 103.3 0.4 1.2e-29 103.1 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) PRP1_N PF06424.7 KFX95665.1 - 4.1e-53 179.2 5.9 1.1e-52 177.9 4.1 1.8 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 KFX95665.1 - 1.8e-31 105.7 24.1 0.0015 18.9 0.1 13.1 4 3 10 14 14 13 9 Tetratricopeptide repeat TPR_16 PF13432.1 KFX95665.1 - 7.1e-22 77.5 17.6 1.2e-05 25.7 0.3 8.1 7 1 0 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFX95665.1 - 1e-21 77.0 21.1 4.8e-07 30.0 0.2 9.5 5 3 3 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 KFX95665.1 - 4.9e-14 51.7 8.5 0.00065 19.2 0.0 7.8 6 2 2 8 8 8 4 TPR repeat TPR_2 PF07719.12 KFX95665.1 - 7.6e-13 47.3 8.2 0.23 11.4 0.0 9.5 11 0 0 11 11 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFX95665.1 - 1.3e-07 31.2 2.5 8.8 6.8 0.0 8.5 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_15 PF13429.1 KFX95665.1 - 1.9e-07 30.4 17.5 1.8e-05 23.9 2.7 5.8 2 2 1 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFX95665.1 - 5.1e-07 29.0 0.1 0.54 9.9 0.0 5.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFX95665.1 - 6.1e-06 25.6 0.3 3.4 7.6 0.0 6.5 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFX95665.1 - 4.6e-05 23.6 7.5 38 5.0 0.0 8.6 9 0 0 9 9 8 0 Tetratricopeptide repeat Suf PF05843.9 KFX95665.1 - 0.00016 21.5 2.3 0.99 9.0 0.0 4.8 5 1 0 5 5 5 2 Suppressor of forked protein (Suf) TPR_9 PF13371.1 KFX95665.1 - 0.00029 20.6 3.2 2.2 8.1 0.0 5.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFX95665.1 - 0.00067 19.5 3.4 1.7 8.6 0.0 5.7 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.4 KFX95665.1 - 0.0016 18.4 14.5 0.027 14.4 0.6 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat DUF3808 PF10300.4 KFX95665.1 - 0.0028 16.3 0.6 2.2 6.7 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3808) NARP1 PF12569.3 KFX95665.1 - 0.0083 14.9 13.0 0.033 12.9 0.0 5.4 4 1 3 7 7 7 1 NMDA receptor-regulated protein 1 Apc3 PF12895.2 KFX95665.1 - 0.011 15.8 0.0 0.72 10.0 0.0 3.8 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 RrnaAD PF00398.15 KFX95666.1 - 7.7e-58 195.5 0.0 1e-57 195.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KFX95666.1 - 1.4e-10 41.2 0.0 2.5e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX95666.1 - 3e-07 31.0 0.0 6e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX95666.1 - 9.1e-05 21.9 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KFX95666.1 - 0.0001 21.8 0.0 0.00015 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 KFX95666.1 - 0.00026 20.1 0.0 0.0004 19.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 KFX95666.1 - 0.00046 20.6 0.0 0.001 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KFX95666.1 - 0.00056 19.1 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Met_10 PF02475.11 KFX95666.1 - 0.0011 18.6 0.1 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.1 KFX95666.1 - 0.0011 18.7 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX95666.1 - 0.0013 18.3 0.0 0.0019 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX95666.1 - 0.01 16.2 0.0 0.031 14.7 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase domain UPF0020 PF01170.13 KFX95666.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.13 KFX95666.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family adh_short PF00106.20 KFX95667.1 - 8.1e-20 71.3 0.6 1.3e-19 70.6 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX95667.1 - 2.1e-09 37.2 0.2 2.8e-09 36.8 0.2 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFX95667.1 - 3.4e-09 36.8 0.0 4.2e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFX95667.1 - 5.7e-05 22.6 0.0 8.3e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX95667.1 - 0.0035 17.3 0.2 0.01 15.8 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFX95667.1 - 0.017 13.8 0.2 0.025 13.2 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Dimer_Tnp_hAT PF05699.9 KFX95668.1 - 3e-21 74.8 0.0 7e-21 73.6 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 KFX95668.1 - 1.2e-06 28.3 0.8 1.2e-06 28.3 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) Phosphoesterase PF04185.9 KFX95674.1 - 4.4e-62 210.4 2.8 6.4e-62 209.9 2.0 1.2 1 0 0 1 1 1 1 Phosphoesterase family VIT1 PF01988.14 KFX95675.1 - 2.1e-56 190.7 3.0 2.5e-56 190.5 2.1 1.0 1 0 0 1 1 1 1 VIT family Pyr_redox_3 PF13738.1 KFX95676.1 - 9.1e-26 91.1 0.0 1.1e-25 90.8 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFX95676.1 - 1.9e-15 56.6 0.0 1.7e-11 43.6 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KFX95676.1 - 8e-11 40.8 0.0 1.1e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KFX95676.1 - 2.3e-06 27.6 0.2 1.5e-05 24.9 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX95676.1 - 0.0003 20.7 0.0 0.00068 19.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KFX95676.1 - 0.0011 18.0 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein GDI PF00996.13 KFX95676.1 - 0.0032 15.8 0.0 0.0042 15.4 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_9 PF13454.1 KFX95676.1 - 0.0034 17.1 0.0 0.011 15.5 0.0 1.8 1 1 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.12 KFX95676.1 - 0.012 14.7 0.0 0.031 13.3 0.0 1.7 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KFX95676.1 - 0.013 15.8 0.0 2.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFX95676.1 - 0.061 11.7 0.0 2 6.7 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein zf-HC5HC2H PF13771.1 KFX95678.1 - 0.0027 17.8 2.2 0.0042 17.1 1.5 1.3 1 0 0 1 1 1 1 PHD-like zinc-binding domain GIY-YIG PF01541.19 KFX95678.1 - 0.0033 17.7 0.0 0.0058 16.9 0.0 1.3 1 0 0 1 1 1 1 GIY-YIG catalytic domain Pput2613-deam PF14427.1 KFX95678.1 - 0.0088 15.7 0.1 0.02 14.5 0.0 1.6 1 1 0 1 1 1 1 Pput_2613-like deaminase zf-HC5HC2H_2 PF13832.1 KFX95678.1 - 0.013 15.5 0.7 0.021 14.7 0.5 1.3 1 0 0 1 1 1 0 PHD-zinc-finger like domain PHD PF00628.24 KFX95678.1 - 0.29 10.8 3.7 0.56 9.9 2.6 1.5 1 1 0 1 1 1 0 PHD-finger DEAD PF00270.24 KFX95679.1 - 1e-40 139.0 0.2 2.3e-40 137.8 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX95679.1 - 3.1e-29 100.6 0.2 6.1e-29 99.7 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KFX95679.1 - 0.0067 16.1 0.1 0.017 14.9 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain SecA_DEAD PF07517.9 KFX95679.1 - 0.0076 15.5 0.3 0.016 14.5 0.0 1.5 2 0 0 2 2 2 1 SecA DEAD-like domain AAA_30 PF13604.1 KFX95679.1 - 0.013 15.1 0.5 0.03 13.9 0.3 1.6 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 KFX95679.1 - 0.03 14.1 0.1 0.074 12.8 0.1 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 KFX95679.1 - 0.062 13.0 0.2 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain tRNA-synt_1b PF00579.20 KFX95679.1 - 0.12 11.4 0.0 0.28 10.2 0.0 1.6 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) Helicase_RecD PF05127.9 KFX95679.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.1 KFX95679.1 - 0.17 12.0 0.5 0.76 9.9 0.4 2.0 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.3 KFX95680.1 - 1.6e-69 233.4 0.0 3.5e-69 232.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 KFX95680.1 - 8e-11 41.2 0.2 1.5e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 KFX95680.1 - 3.2e-08 33.4 1.8 2.5e-06 27.4 0.3 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFX95680.1 - 4.4e-07 29.8 4.6 9.5e-07 28.7 0.2 2.6 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFX95680.1 - 0.0029 17.6 0.2 0.063 13.3 0.0 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Myb_CC_LHEQLE PF14379.1 KFX95680.1 - 0.012 15.1 2.9 0.3 10.6 0.8 2.6 2 0 0 2 2 2 0 MYB-CC type transfactor, LHEQLE motif zf-C2H2 PF00096.21 KFX95680.1 - 0.025 14.9 3.7 0.33 11.3 0.2 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF951 PF06107.6 KFX95680.1 - 0.058 12.9 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) zf-C2H2_4 PF13894.1 KFX95680.1 - 0.11 12.8 3.5 2.8 8.4 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-U1 PF06220.7 KFX95680.1 - 0.13 11.8 0.1 0.31 10.6 0.1 1.7 1 0 0 1 1 1 0 U1 zinc finger Vmethyltransf_C PF08456.5 KFX95680.1 - 0.66 9.3 3.1 0.99 8.7 0.0 2.5 3 0 0 3 3 3 0 Viral methyltransferase C-terminal zf-DBF PF07535.7 KFX95680.1 - 1.2 8.8 4.8 0.4 10.4 0.1 2.4 2 1 0 2 2 2 0 DBF zinc finger TOM13 PF08219.6 KFX95681.1 - 1.7e-28 98.2 0.0 2.2e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Outer membrane protein TOM13 Hamartin PF04388.7 KFX95683.1 - 0.82 8.2 3.9 0.98 8.0 2.7 1.0 1 0 0 1 1 1 0 Hamartin protein AMP-binding PF00501.23 KFX95684.1 - 3.7e-40 137.5 0.0 4.6e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 KFX95685.1 - 1.3e-36 125.9 0.0 1.7e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX95685.1 - 3.6e-10 40.6 0.1 5.2e-09 36.9 0.1 2.4 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sporozoite_P67 PF05642.6 KFX95685.1 - 0.21 9.3 3.5 0.26 9.0 2.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3774 PF12609.3 KFX95685.1 - 0.89 10.4 4.3 1.6 9.6 3.0 1.3 1 0 0 1 1 1 0 Wound-induced protein PUF PF00806.14 KFX95692.1 - 1.4e-11 43.1 0.1 0.021 14.3 0.0 6.1 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat Helicase_C_4 PF13871.1 KFX95692.1 - 0.11 11.8 0.1 0.24 10.7 0.1 1.5 1 0 0 1 1 1 0 Helicase_C-like MFS_1 PF07690.11 KFX95693.1 - 3.9e-21 75.1 38.0 1.3e-15 57.0 14.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX95693.1 - 1.2e-18 66.9 6.9 1.2e-18 66.9 4.8 2.4 2 2 0 2 2 2 2 Sugar (and other) transporter CN_hydrolase PF00795.17 KFX95694.1 - 3.4e-14 52.6 0.0 7.6e-14 51.4 0.0 1.6 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase SnoaL PF07366.7 KFX95695.1 - 2.5e-21 75.5 0.0 3.9e-14 52.3 0.0 2.4 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KFX95695.1 - 2.2e-13 50.4 0.0 1.3e-08 35.1 0.0 2.3 2 0 0 2 2 2 2 SnoaL-like domain Alpha-amylase PF00128.19 KFX95697.1 - 1.3e-99 333.5 0.1 1.3e-99 333.5 0.0 1.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KFX95697.1 - 0.00097 18.1 0.0 0.0017 17.3 0.0 1.3 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Alpha-amylase_C PF02806.13 KFX95697.1 - 0.0064 16.5 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Fungal_trans_2 PF11951.3 KFX95698.1 - 1.4e-51 175.2 4.9 2.1e-51 174.7 3.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX95698.1 - 2.3e-07 30.5 9.5 4.5e-07 29.6 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cupin_7 PF12973.2 KFX95699.1 - 2.4e-11 43.3 0.1 3.4e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 ChrR Cupin-like domain DUF4437 PF14499.1 KFX95699.1 - 0.073 11.9 0.3 0.1 11.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) Cupin_2 PF07883.6 KFX95699.1 - 0.28 10.7 3.2 0.37 10.3 1.4 1.8 1 1 1 2 2 2 0 Cupin domain Aminotran_3 PF00202.16 KFX95700.1 - 7.8e-86 287.9 0.0 9.4e-86 287.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF4219 PF13961.1 KFX95711.1 - 8.3e-10 37.8 0.0 1.4e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) DUF4219 PF13961.1 KFX95712.1 - 3.9e-11 42.0 0.1 8.4e-11 41.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Ran_BP1 PF00638.13 KFX95723.1 - 1.9e-48 163.5 2.2 4.2e-48 162.4 1.5 1.6 1 0 0 1 1 1 1 RanBP1 domain A_deaminase PF00962.17 KFX95723.1 - 2.4e-38 131.8 0.0 4.1e-38 131.1 0.0 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase WH1 PF00568.18 KFX95723.1 - 0.0021 17.7 0.4 0.0085 15.8 0.3 2.0 1 1 0 1 1 1 1 WH1 domain YEATS PF03366.11 KFX95724.1 - 1.2e-21 76.1 0.0 2.1e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 YEATS family DUF3083 PF11281.3 KFX95724.1 - 0.0095 15.0 0.0 0.018 14.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3083) REV PF00424.13 KFX95724.1 - 0.1 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) DUF4604 PF15377.1 KFX95725.1 - 1.4e-19 70.8 14.3 1.6e-19 70.7 9.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Glyco_transf_15 PF01793.11 KFX95726.1 - 2e-133 444.4 1.1 2.6e-133 444.0 0.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase UDPGP PF01704.13 KFX95726.1 - 0.017 13.6 0.0 0.024 13.1 0.0 1.1 1 0 0 1 1 1 0 UTP--glucose-1-phosphate uridylyltransferase CIA30 PF08547.7 KFX95735.1 - 6.3e-43 146.3 0.0 8.6e-43 145.9 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Apc5 PF12862.2 KFX95736.1 - 1.3e-34 117.9 2.2 4e-34 116.3 1.5 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 PMAIP1 PF15150.1 KFX95736.1 - 0.019 14.7 0.2 0.055 13.2 0.1 1.8 1 0 0 1 1 1 0 Phorbol-12-myristate-13-acetate-induced TPR_21 PF09976.4 KFX95736.1 - 0.077 12.9 0.6 19 5.1 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFX95736.1 - 0.093 13.0 7.5 1.6 9.0 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFX95736.1 - 0.097 12.6 2.0 62 3.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFX95736.1 - 2 9.2 6.8 46 5.0 0.1 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFX95736.1 - 5.7 7.6 8.1 41 5.0 0.9 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFX95736.1 - 7.5 7.3 9.8 42 4.9 0.6 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFX95736.1 - 8.5 6.5 7.8 9.5 6.4 0.2 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat COX6A PF02046.10 KFX95737.1 - 6.1e-45 151.8 2.3 6.4e-45 151.8 1.6 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa PSK_trans_fac PF07704.6 KFX95737.1 - 0.13 12.9 2.5 0.21 12.2 1.7 1.4 1 0 0 1 1 1 0 Rv0623-like transcription factor Exo_endo_phos PF03372.18 KFX95738.1 - 1.2e-18 68.0 0.0 1.8e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KFX95738.1 - 6e-15 54.9 0.0 3e-14 52.6 0.0 2.2 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 KFX95738.1 - 0.00026 20.8 1.4 0.00078 19.3 1.0 1.9 1 0 0 1 1 1 1 GRF zinc finger HMG_box PF00505.14 KFX95739.1 - 4e-16 59.0 0.5 6.8e-16 58.2 0.4 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFX95739.1 - 0.024 14.9 0.5 0.039 14.3 0.3 1.3 1 0 0 1 1 1 0 HMG-box domain MAT_Alpha1 PF04769.7 KFX95741.1 - 2.7e-41 141.1 0.1 4e-41 140.5 0.1 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 ANTH PF07651.11 KFX95742.1 - 5.9e-79 264.6 0.0 5.9e-79 264.6 0.0 2.4 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.12 KFX95742.1 - 5.5e-64 214.7 6.5 5.5e-64 214.7 4.5 5.7 5 1 0 6 6 6 2 I/LWEQ domain Med15 PF09606.5 KFX95742.1 - 4.8 5.2 37.9 12 3.9 26.3 1.6 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DNA_pol_B PF00136.16 KFX95743.1 - 7.3e-89 298.6 0.0 1.4e-88 297.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B DUF2404 PF10296.4 KFX95743.1 - 4.4e-29 100.4 0.0 1e-28 99.2 0.0 1.7 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DNA_pol_B_exo1 PF03104.14 KFX95743.1 - 2.1e-22 79.3 0.0 6.9e-12 44.8 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KFX95743.1 - 8e-18 64.2 5.9 1.9e-17 62.9 4.1 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DZR PF12773.2 KFX95743.1 - 7.9 6.3 4.8 7 6.5 0.8 1.7 1 1 1 2 2 2 0 Double zinc ribbon Slu7 PF11708.3 KFX95744.1 - 7.5e-77 258.2 15.9 7.5e-77 258.2 11.0 2.0 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 KFX95744.1 - 0.0092 15.6 1.1 0.016 14.8 0.8 1.4 1 0 0 1 1 1 1 Zinc knuckle Ribosomal_S4 PF00163.14 KFX95745.1 - 6.9e-30 103.2 1.2 1.4e-29 102.3 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KFX95745.1 - 2.6e-12 45.9 1.3 2.6e-12 45.9 0.9 2.5 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 KFX95746.1 - 2.2e-40 136.4 6.6 1.3e-38 130.7 3.6 2.1 1 1 1 2 2 2 2 Ribosomal protein L21e CN_hydrolase PF00795.17 KFX95747.1 - 3.3e-12 46.1 0.0 5e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Abhydrolase_6 PF12697.2 KFX95750.1 - 1.3e-19 70.9 0.0 1.7e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX95750.1 - 1.1e-10 41.4 0.0 1.5e-10 40.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX95750.1 - 5.1e-05 22.9 0.0 0.0076 15.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Zeta_toxin PF06414.7 KFX95750.1 - 0.023 13.7 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin CBM_1 PF00734.13 KFX95751.1 - 2.7e-06 26.9 11.4 2.7e-06 26.9 7.9 3.3 3 0 0 3 3 3 1 Fungal cellulose binding domain Abhydrolase_5 PF12695.2 KFX95751.1 - 2.3e-05 24.1 0.0 3.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KFX95751.1 - 0.0028 16.9 0.6 0.011 15.0 0.2 2.0 1 1 0 2 2 2 1 Esterase PHB depolymerase Esterase PF00756.15 KFX95751.1 - 0.0041 16.5 0.8 0.02 14.3 0.6 1.9 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 KFX95751.1 - 0.0075 15.5 0.1 0.029 13.6 0.1 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KFX95751.1 - 0.024 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KFX95751.1 - 0.039 13.8 0.0 0.05 13.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family MLTD_N PF06474.7 KFX95751.1 - 0.065 13.4 0.4 0.17 12.1 0.3 1.7 1 0 0 1 1 1 0 MltD lipid attachment motif MSP1_C PF07462.6 KFX95751.1 - 0.3 9.4 0.2 0.39 9.0 0.1 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Glyco_hydro_62 PF03664.8 KFX95752.1 - 9.9e-148 490.5 11.3 1.2e-147 490.2 7.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.13 KFX95752.1 - 4.6e-12 45.3 15.9 1.4e-11 43.8 11.1 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_10 PF00331.15 KFX95753.1 - 4.1e-103 344.7 0.2 4.7e-103 344.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 KFX95753.1 - 3.3e-08 33.0 7.8 3.3e-08 33.0 5.4 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Cellulase PF00150.13 KFX95754.1 - 2.9e-51 174.3 0.1 4e-51 173.8 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KFX95754.1 - 3.5e-12 45.7 14.0 3.5e-12 45.7 9.7 3.4 3 0 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KFX95754.1 - 0.52 10.3 3.8 1.3 9.1 2.6 1.7 1 0 0 1 1 1 0 Toxin 7 MMS1_N PF10433.4 KFX95759.1 - 1.8e-80 270.5 0.0 2.6e-80 270.0 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 KFX95759.1 - 1.2e-68 231.5 0.0 3.9e-68 229.9 0.0 1.9 2 0 0 2 2 2 1 CPSF A subunit region Pmp3 PF01679.12 KFX95760.1 - 1.4e-19 69.5 5.8 1.7e-19 69.2 4.0 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Sin_N PF04801.8 KFX95761.1 - 6.9e-30 104.2 0.0 8.8e-17 61.0 0.0 2.0 2 0 0 2 2 2 2 Sin-like protein conserved region Clp1 PF06807.9 KFX95762.1 - 2.2e-26 92.8 0.0 3.5e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KFX95762.1 - 9.6e-14 51.2 0.0 1.7e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 KFX95762.1 - 2.6e-08 33.7 0.0 2.9e-07 30.2 0.0 2.2 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 KFX95762.1 - 3.5e-06 26.9 0.1 1.9e-05 24.5 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KFX95762.1 - 0.00014 21.9 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.4 KFX95762.1 - 0.00087 18.7 0.0 0.69 9.3 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 KFX95762.1 - 0.0016 18.2 0.3 1.3 8.8 0.0 2.6 2 1 1 3 3 3 2 Dynamin family SRPRB PF09439.5 KFX95762.1 - 0.003 16.7 0.0 0.0075 15.4 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 KFX95762.1 - 0.0033 16.9 0.0 0.0054 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_21 PF13304.1 KFX95762.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 KFX95762.1 - 0.011 15.1 0.0 0.43 9.9 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 KFX95762.1 - 0.055 13.7 0.0 0.096 12.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_35 PF14516.1 KFX95762.1 - 0.077 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain T2SE PF00437.15 KFX95762.1 - 0.099 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 KFX95762.1 - 0.14 11.8 0.0 0.39 10.3 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase cobW PF02492.14 KFX95762.1 - 0.15 11.4 0.0 0.68 9.3 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain BUD22 PF09073.5 KFX95763.1 - 0.0028 16.7 9.4 0.0044 16.1 6.5 1.2 1 0 0 1 1 1 1 BUD22 HEAT_2 PF13646.1 KFX95763.1 - 0.0074 16.5 1.2 0.32 11.3 0.0 3.1 3 0 0 3 3 3 1 HEAT repeats Arm PF00514.18 KFX95763.1 - 0.011 15.5 1.9 0.32 10.9 0.1 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KFX95763.1 - 0.035 14.6 4.3 1.3 9.6 0.1 4.0 4 0 0 4 4 4 0 HEAT-like repeat Baculo_PEP_C PF04513.7 KFX95763.1 - 0.16 11.7 2.7 2 8.2 0.3 2.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Daxx PF03344.10 KFX95763.1 - 0.2 10.1 9.8 0.27 9.6 6.8 1.1 1 0 0 1 1 1 0 Daxx Family TFIIF_alpha PF05793.7 KFX95763.1 - 0.22 9.8 8.0 0.33 9.2 5.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RRN3 PF05327.6 KFX95763.1 - 3.3 5.7 7.2 5.4 5.0 5.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 NUDIX PF00293.23 KFX95764.1 - 1.8e-22 79.4 0.0 3.2e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_7 PF13508.1 KFX95764.1 - 1.3e-09 38.0 0.0 3.3e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX95764.1 - 3.6e-08 33.3 0.0 1.9e-07 31.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KFX95764.1 - 7.3e-06 25.8 0.0 2e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX95764.1 - 0.002 18.2 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFX95764.1 - 0.0031 17.3 0.0 0.006 16.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 KFX95764.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RPA_C PF08784.6 KFX95765.1 - 6.7e-16 58.5 0.0 1.8e-15 57.1 0.0 1.7 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 KFX95765.1 - 1.1e-10 41.1 0.1 1.9e-10 40.4 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain FluMu_gp41 PF10109.4 KFX95765.1 - 0.15 12.0 0.1 2.3 8.2 0.0 2.4 1 1 1 2 2 2 0 Mu-like prophage FluMu protein gp41 DnaJ PF00226.26 KFX95766.1 - 3.5e-14 52.2 0.7 3.5e-14 52.2 0.5 2.5 3 0 0 3 3 3 1 DnaJ domain Lon_C PF05362.8 KFX95767.1 - 4.3e-66 222.1 0.4 8.7e-66 221.1 0.3 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KFX95767.1 - 2.7e-26 92.5 0.0 6.4e-26 91.3 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KFX95767.1 - 1.5e-23 83.4 0.0 5.6e-23 81.5 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 KFX95767.1 - 2.6e-09 36.6 0.0 5.4e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 KFX95767.1 - 7.2e-09 35.4 0.0 1.9e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KFX95767.1 - 8.4e-07 28.5 0.0 1.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 KFX95767.1 - 7.6e-06 26.0 0.0 4e-05 23.6 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KFX95767.1 - 1.6e-05 25.7 0.0 5.2e-05 24.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KFX95767.1 - 2.6e-05 23.8 0.0 8e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KFX95767.1 - 3.2e-05 23.9 0.0 8.6e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KFX95767.1 - 4.7e-05 22.5 0.1 0.00019 20.5 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KFX95767.1 - 0.00055 19.8 0.0 0.0016 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFX95767.1 - 0.00056 20.0 0.0 0.0053 16.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFX95767.1 - 0.0011 18.6 0.0 0.0041 16.8 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 KFX95767.1 - 0.0013 17.5 0.1 0.0032 16.2 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus AAA_33 PF13671.1 KFX95767.1 - 0.0025 17.6 0.0 0.0068 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFX95767.1 - 0.0046 16.3 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KFX95767.1 - 0.0054 16.8 0.0 0.02 15.0 0.0 2.0 2 0 0 2 2 1 1 RNA helicase Zeta_toxin PF06414.7 KFX95767.1 - 0.0087 15.1 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 KFX95767.1 - 0.0089 15.6 0.0 0.023 14.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 KFX95767.1 - 0.012 15.8 0.1 0.03 14.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KFX95767.1 - 0.014 15.7 0.0 0.014 15.7 0.0 2.6 2 1 0 2 2 1 0 AAA domain AAA_24 PF13479.1 KFX95767.1 - 0.018 14.6 0.1 0.035 13.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KFX95767.1 - 0.02 14.5 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 KFX95767.1 - 0.02 14.5 0.0 0.47 10.1 0.0 2.7 1 1 1 2 2 2 0 Archaeal ATPase Mg_chelatase PF01078.16 KFX95767.1 - 0.024 13.7 0.1 0.073 12.2 0.1 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 KFX95767.1 - 0.034 13.3 0.0 0.069 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 KFX95767.1 - 0.046 13.4 0.6 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 NTPase AAA_PrkA PF08298.6 KFX95767.1 - 0.052 12.2 0.1 0.48 9.0 0.1 2.1 2 0 0 2 2 2 0 PrkA AAA domain MobB PF03205.9 KFX95767.1 - 0.063 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 KFX95767.1 - 0.066 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 KFX95767.1 - 0.069 13.4 0.0 0.26 11.5 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 KFX95767.1 - 0.12 11.7 0.1 0.32 10.3 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain G-alpha PF00503.15 KFX95767.1 - 0.13 10.9 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Rad17 PF03215.10 KFX95767.1 - 0.13 10.9 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Abhydrolase_6 PF12697.2 KFX95780.1 - 9.4e-23 81.2 0.3 1.3e-22 80.7 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX95780.1 - 3.9e-19 68.8 0.0 8e-19 67.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFX95780.1 - 1.9e-13 50.0 2.1 3.4e-13 49.2 1.5 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 KFX95780.1 - 8.9e-10 38.5 0.0 3.1e-06 26.9 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFX95780.1 - 3.3e-07 29.7 0.0 0.00053 19.2 0.0 2.4 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KFX95780.1 - 9.9e-05 21.8 0.0 0.95 8.8 0.0 3.2 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.2 KFX95780.1 - 0.0012 17.7 0.3 0.0028 16.6 0.2 1.6 1 0 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.7 KFX95780.1 - 0.0022 16.5 0.0 0.55 8.6 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Chlorophyllase PF07224.6 KFX95780.1 - 0.0034 16.2 0.4 0.0048 15.7 0.3 1.2 1 0 0 1 1 1 1 Chlorophyllase Ser_hydrolase PF06821.8 KFX95780.1 - 0.0035 16.9 0.0 0.0064 16.0 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_8 PF06259.7 KFX95780.1 - 0.011 15.2 0.1 0.037 13.5 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase PAF-AH_p_II PF03403.8 KFX95780.1 - 0.027 12.7 0.2 0.92 7.7 0.0 2.0 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II PGAP1 PF07819.8 KFX95780.1 - 0.038 13.5 0.1 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 KFX95780.1 - 0.065 12.8 0.3 0.099 12.2 0.2 1.3 1 0 0 1 1 1 0 Lipase (class 3) Zn_clus PF00172.13 KFX95781.1 - 2.1e-05 24.3 9.3 4.1e-05 23.3 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Imm38 PF15599.1 KFX95781.1 - 0.1 12.1 0.1 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 38 CFEM PF05730.6 KFX95783.1 - 2.4e-11 43.2 16.4 3.5e-11 42.7 11.4 1.3 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.15 KFX95783.1 - 0.044 13.8 1.2 0.087 12.8 0.8 1.5 1 0 0 1 1 1 0 Gamma-thionin family Sugar_tr PF00083.19 KFX95784.1 - 1.3e-59 202.0 24.9 1.5e-59 201.8 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX95784.1 - 2.1e-19 69.4 38.6 2.1e-19 69.4 26.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.23 KFX95785.1 - 9.9e-249 824.6 0.0 6.5e-84 281.7 0.0 3.4 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KFX95785.1 - 1e-115 385.7 0.1 3.3e-43 147.6 0.0 3.3 3 0 0 3 3 3 3 Condensation domain PP-binding PF00550.20 KFX95785.1 - 3e-33 113.8 2.3 2.4e-11 43.7 0.0 4.9 4 0 0 4 4 4 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KFX95785.1 - 1.5e-13 51.4 0.0 0.001 20.0 0.0 4.1 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain adh_short PF00106.20 KFX95789.1 - 3.6e-27 95.2 3.3 4.4e-27 95.0 1.9 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX95789.1 - 9.7e-21 74.6 0.8 2.2e-20 73.4 0.5 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX95789.1 - 2.9e-12 46.6 2.0 5.8e-12 45.6 1.4 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KFX95789.1 - 0.0077 15.1 0.0 0.0099 14.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 KFX95789.1 - 0.016 14.9 0.3 0.056 13.2 0.2 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ThiF PF00899.16 KFX95789.1 - 0.11 12.3 0.5 0.28 10.9 0.4 1.7 1 1 0 1 1 1 0 ThiF family ADK PF00406.17 KFX95791.1 - 3.7e-47 159.9 0.0 4.5e-47 159.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 KFX95791.1 - 3.1e-09 37.2 0.0 4.6e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KFX95791.1 - 1.6e-08 34.1 0.5 0.0034 16.7 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_17 PF13207.1 KFX95791.1 - 5.9e-08 33.5 0.0 7.7e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFX95791.1 - 2.2e-06 27.6 0.0 6.8e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KFX95791.1 - 0.01 16.0 0.2 0.15 12.2 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KFX95791.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.3 1 1 0 1 1 1 0 Zeta toxin PD40 PF07676.7 KFX95791.1 - 0.042 13.5 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat SRP54 PF00448.17 KFX95791.1 - 0.1 12.0 0.1 0.16 11.3 0.0 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Dicty_REP PF05086.7 KFX95799.1 - 0.28 8.8 0.3 0.42 8.3 0.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MFS_1 PF07690.11 KFX95808.1 - 1.3e-23 83.3 45.0 1.9e-23 82.7 31.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Autotransporter PF03797.14 KFX95808.1 - 0.091 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Autotransporter beta-domain Peptidase_C48 PF02902.14 KFX95809.1 - 8e-07 28.8 0.0 1.6e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Acetyltransf_3 PF13302.1 KFX95810.1 - 5.3e-14 52.5 0.0 6.3e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX95810.1 - 1.5e-08 34.5 0.0 2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KFX95810.1 - 8.1e-07 29.0 0.0 1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFX95810.1 - 0.0035 17.4 0.0 0.0044 17.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFX95810.1 - 0.0065 16.4 0.0 0.0088 15.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Peptidase_S10 PF00450.17 KFX95811.1 - 3.8e-86 289.8 0.7 5.6e-86 289.2 0.5 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Sulfatase PF00884.18 KFX95812.1 - 3.4e-77 259.6 0.0 4.2e-77 259.3 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 KFX95812.1 - 0.0001 20.8 0.0 0.0012 17.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Phosphodiest PF01663.17 KFX95812.1 - 0.00063 19.1 0.0 0.035 13.4 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 KFX95812.1 - 0.17 12.2 1.7 1.8 8.8 0.1 2.5 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase Sugar_tr PF00083.19 KFX95813.1 - 1.2e-111 373.5 28.7 1.3e-111 373.3 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX95813.1 - 1.4e-18 66.7 32.6 1.4e-17 63.4 17.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 KFX95813.1 - 8 5.9 17.2 0.72 9.3 0.7 3.0 3 1 0 3 3 3 0 Ion channel regulatory protein UNC-93 Rib_5-P_isom_A PF06026.9 KFX95814.1 - 2.5e-39 134.3 0.0 6.8e-34 116.6 0.0 3.1 3 0 0 3 3 3 3 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 KFX95814.1 - 0.13 11.8 0.0 17 5.0 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain Zn_clus PF00172.13 KFX95815.1 - 5.7e-20 70.9 24.4 1.8e-10 40.5 6.5 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX95815.1 - 9.6e-09 34.4 0.2 1.7e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Alginate_lyase2 PF08787.6 KFX95816.1 - 6.5e-52 176.5 0.0 7.3e-52 176.3 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase Polysacc_lyase PF14099.1 KFX95816.1 - 0.00012 21.8 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide lyase Abhydrolase_3 PF07859.8 KFX95817.1 - 1.4e-34 119.5 0.0 1.9e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KFX95817.1 - 3.8e-06 25.9 0.6 1.5e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_2 PF02230.11 KFX95817.1 - 7.6e-06 25.5 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KFX95817.1 - 1.3e-05 24.9 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KFX95817.1 - 0.045 13.0 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Esterase_phd PF10503.4 KFX95817.1 - 0.051 12.8 1.1 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase DUF2974 PF11187.3 KFX95817.1 - 0.078 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Peptidase_S9 PF00326.16 KFX95817.1 - 0.094 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family AXE1 PF05448.7 KFX95817.1 - 0.1 11.0 0.0 0.19 10.1 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF2424 PF10340.4 KFX95817.1 - 0.13 10.8 0.0 0.27 9.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) RTA1 PF04479.8 KFX95818.1 - 9.7e-42 142.9 8.3 1.5e-41 142.4 5.7 1.2 1 0 0 1 1 1 1 RTA1 like protein Thioesterase PF00975.15 KFX95819.1 - 1.5e-14 54.8 0.1 2.8e-14 53.9 0.0 1.4 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 KFX95819.1 - 6.5e-11 42.5 0.3 7.5e-11 42.3 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX95819.1 - 0.00049 19.7 0.0 0.00055 19.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX95819.1 - 0.0017 18.1 0.0 0.0019 17.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX95820.1 - 8.1e-13 48.3 0.0 3.5e-12 46.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX95820.1 - 8e-12 45.5 0.0 1.6e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFX95820.1 - 1.6e-07 30.7 0.4 4.1e-07 29.4 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KFX95820.1 - 0.0067 16.0 0.3 0.025 14.1 0.1 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 KFX95820.1 - 0.061 12.6 0.0 0.82 8.9 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family BAAT_C PF08840.6 KFX95820.1 - 0.12 12.0 0.0 0.54 9.9 0.0 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PAF-AH_p_II PF03403.8 KFX95820.1 - 0.13 10.5 0.0 0.19 10.0 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II MFS_1 PF07690.11 KFX95821.1 - 5.8e-36 123.9 79.6 1.4e-28 99.6 36.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFX95821.1 - 0.095 12.5 6.8 0.033 13.9 1.3 2.7 3 0 0 3 3 3 0 MFS_1 like family Sugar_tr PF00083.19 KFX95821.1 - 0.12 10.9 42.0 0.53 8.8 11.3 2.5 2 1 0 2 2 2 0 Sugar (and other) transporter Fungal_trans PF04082.13 KFX95822.1 - 2.2e-15 56.2 0.3 3.6e-15 55.5 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain COesterase PF00135.23 KFX95824.1 - 1.1e-74 252.0 0.0 2e-74 251.2 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX95824.1 - 1.5e-14 54.1 0.9 7.4e-14 51.8 0.6 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFX95824.1 - 0.00031 20.0 0.2 0.00063 19.0 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFX95824.1 - 0.007 16.1 0.4 0.012 15.3 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3815 PF12821.2 KFX95824.1 - 0.04 13.8 0.2 0.099 12.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3815) GMC_oxred_N PF00732.14 KFX95825.1 - 2.3e-62 210.8 0.0 3.4e-62 210.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFX95825.1 - 1.9e-31 109.2 0.3 4.2e-31 108.1 0.2 1.6 1 0 0 1 1 1 1 GMC oxidoreductase F-box-like PF12937.2 KFX95825.1 - 1.8e-09 37.1 0.1 3.4e-09 36.2 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX95825.1 - 2.8e-09 36.3 0.0 6.3e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain DAO PF01266.19 KFX95825.1 - 0.00046 19.2 0.0 0.0071 15.2 0.0 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX95825.1 - 0.0052 16.7 0.0 0.02 14.9 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KFX95825.1 - 0.052 13.5 0.0 6.2 6.8 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase WD40 PF00400.27 KFX95825.1 - 0.084 12.7 0.0 2.8 7.9 0.0 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat Thi4 PF01946.12 KFX95825.1 - 0.46 9.5 0.5 0.93 8.5 0.0 1.7 2 0 0 2 2 2 0 Thi4 family HSP20 PF00011.16 KFX95826.1 - 5.3e-17 61.5 0.0 2.8e-12 46.4 0.1 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family MFS_1 PF07690.11 KFX95827.1 - 1.6e-05 23.8 31.9 0.00014 20.7 19.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily PsbH PF00737.15 KFX95827.1 - 0.032 13.8 0.6 0.11 12.1 0.4 1.9 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Glyoxalase_2 PF12681.2 KFX95828.1 - 1.1e-06 29.2 0.0 1.2e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KFX95828.1 - 5.6e-05 23.1 0.0 6.8e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fungal_trans_2 PF11951.3 KFX95829.1 - 6.7e-07 28.2 0.2 1.4e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain BRO1 PF03097.13 KFX95829.1 - 0.075 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 BRO1-like domain MFS_1 PF07690.11 KFX95830.1 - 2.9e-14 52.5 32.7 3.8e-14 52.1 22.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.17 KFX95831.1 - 1.1e-15 57.2 0.0 7.6e-15 54.3 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Pro_CA PF00484.14 KFX95831.1 - 5.4e-13 49.2 0.0 9.1e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Carbonic anhydrase ATP-synt_C PF00137.16 KFX95832.1 - 1.6e-27 95.1 31.5 5.1e-17 61.5 10.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C TCR_zetazeta PF11628.3 KFX95832.1 - 8.3 5.9 7.7 11 5.5 1.6 2.5 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 zeta chain MARVEL PF01284.18 KFX95833.1 - 2.2e-14 53.4 12.4 2.7e-14 53.2 8.6 1.0 1 0 0 1 1 1 1 Membrane-associating domain Fungal_trans PF04082.13 KFX95834.1 - 5.6e-33 113.9 0.0 8e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX95834.1 - 9.2e-11 41.4 11.7 1.5e-10 40.7 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pput2613-deam PF14427.1 KFX95834.1 - 0.13 11.9 0.6 4.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Pput_2613-like deaminase FSH1 PF03959.8 KFX95843.1 - 8.6e-28 97.2 0.0 9.4e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KFX95843.1 - 0.0011 18.8 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KFX95843.1 - 0.11 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain zf-FPG_IleRS PF06827.9 KFX95844.1 - 0.0016 17.9 0.8 0.37 10.4 0.0 2.4 2 0 0 2 2 2 2 Zinc finger found in FPG and IleRS Yippee-Mis18 PF03226.9 KFX95844.1 - 0.029 14.4 0.1 7.9 6.6 0.1 2.2 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn_Tnp_IS1 PF03811.8 KFX95844.1 - 1 8.8 4.9 5.6 6.5 0.2 2.3 1 1 1 2 2 2 0 InsA N-terminal domain Fer4_6 PF12837.2 KFX95844.1 - 2.5 8.1 4.6 1.3 9.0 0.3 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain WD40 PF00400.27 KFX95850.1 - 1.7e-22 78.4 7.7 7.7e-10 38.2 0.2 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 KFX95850.1 - 4.9e-07 28.2 1.4 0.018 13.2 0.0 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KFX95850.1 - 0.02 14.3 0.6 0.067 12.6 0.3 1.9 1 1 1 2 2 2 0 PQQ-like domain BBS2_Mid PF14783.1 KFX95850.1 - 0.04 13.7 0.0 1.1 8.9 0.0 2.9 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PAT1 PF09770.4 KFX95851.1 - 1e-248 827.7 31.0 1.2e-248 827.5 21.5 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DAGK_cat PF00781.19 KFX95857.1 - 7.8e-16 57.6 0.0 1.1e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Lys PF00062.15 KFX95858.1 - 0.00026 20.9 0.2 0.00036 20.5 0.1 1.2 1 0 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family Bacteriocin_IIc PF10439.4 KFX95858.1 - 0.03 14.4 0.3 0.072 13.2 0.2 1.7 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Fungal_trans PF04082.13 KFX95859.1 - 8.1e-27 93.7 0.0 1e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX95859.1 - 3.3e-09 36.5 9.4 5.1e-09 35.9 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1014 PF06244.7 KFX95860.1 - 1.8e-19 70.1 10.9 5e-19 68.7 7.5 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) CRT10 PF08728.5 KFX95860.1 - 0.96 7.3 3.6 1.1 7.1 2.5 1.0 1 0 0 1 1 1 0 CRT10 TEX19 PF15553.1 KFX95860.1 - 5.9 6.7 6.3 4.3 7.1 1.1 2.1 2 0 0 2 2 2 0 Testis-expressed protein 19 UQ_con PF00179.21 KFX95861.1 - 9.2e-09 34.8 0.0 1.7e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KFX95861.1 - 0.082 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 RWD domain MAD PF05557.8 KFX95862.1 - 4.1e-48 164.0 58.3 4.9e-47 160.4 40.4 2.0 1 1 0 1 1 1 1 Mitotic checkpoint protein Intimin_C PF07979.6 KFX95862.1 - 0.13 12.4 0.0 0.52 10.5 0.0 2.0 1 0 0 1 1 1 0 Intimin C-type lectin domain YqjK PF13997.1 KFX95862.1 - 0.47 10.6 4.1 6 7.1 0.0 3.3 3 0 0 3 3 3 0 YqjK-like protein IL2 PF00715.12 KFX95862.1 - 8.6 6.0 7.7 0.76 9.4 0.8 2.6 3 1 0 3 3 3 0 Interleukin 2 YqeY PF09424.5 KFX95863.1 - 0.037 13.8 1.1 0.042 13.6 0.1 1.5 2 0 0 2 2 2 0 Yqey-like protein DUF1484 PF07363.6 KFX95863.1 - 0.073 13.4 1.9 0.089 13.1 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) DUF737 PF05300.6 KFX95863.1 - 0.13 12.2 4.8 0.14 12.1 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) HAUS6_N PF14661.1 KFX95863.1 - 0.15 11.3 3.3 0.18 11.1 2.3 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus ATP_bind_4 PF01902.12 KFX95866.1 - 6.4e-13 48.5 0.0 3.5e-06 26.5 0.0 3.0 3 0 0 3 3 3 3 ATP-binding region BNR_2 PF13088.1 KFX95873.1 - 4.7e-29 101.5 0.6 7.9e-29 100.7 0.4 1.3 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 KFX95873.1 - 1.1e-10 39.6 24.5 0.05 13.4 0.4 5.9 5 0 0 5 5 5 5 BNR/Asp-box repeat BNR_3 PF13859.1 KFX95873.1 - 0.00054 19.1 0.0 0.001 18.2 0.0 1.4 1 1 0 1 1 1 1 BNR repeat-like domain RNase_H PF00075.19 KFX95875.1 - 2.9e-08 34.1 0.0 3.4e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 RNase H MU117 PF15474.1 KFX95876.1 - 2.6e-07 31.0 6.9 3.8e-07 30.5 4.8 1.2 1 0 0 1 1 1 1 Meiotically up-regulated gene family Tannase PF07519.6 KFX95878.1 - 3.1e-05 22.8 0.2 3.9e-05 22.5 0.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Tannase PF07519.6 KFX95879.1 - 3.7e-90 302.9 0.7 4.8e-90 302.5 0.5 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 KFX95879.1 - 0.07 12.8 0.0 0.11 12.2 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family EutB PF06751.6 KFX95879.1 - 0.13 10.5 0.0 0.2 9.9 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) O-FucT PF10250.4 KFX95881.1 - 8.8e-06 25.0 0.0 0.0028 16.8 0.0 2.9 3 0 0 3 3 3 3 GDP-fucose protein O-fucosyltransferase DUF1282 PF06930.7 KFX95882.1 - 0.0024 17.5 0.2 0.0026 17.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) MARVEL PF01284.18 KFX95882.1 - 0.014 15.2 0.7 0.017 14.9 0.5 1.1 1 0 0 1 1 1 0 Membrane-associating domain Yip1 PF04893.12 KFX95882.1 - 0.024 14.1 1.9 0.027 13.9 1.3 1.1 1 0 0 1 1 1 0 Yip1 domain ABC_membrane PF00664.18 KFX95882.1 - 0.035 13.5 0.1 0.041 13.3 0.1 1.0 1 0 0 1 1 1 0 ABC transporter transmembrane region Tetraspannin PF00335.15 KFX95882.1 - 0.12 11.5 0.8 0.16 11.1 0.5 1.2 1 0 0 1 1 1 0 Tetraspanin family Cation_ATPase_C PF00689.16 KFX95882.1 - 0.18 11.3 1.0 1.3 8.5 0.5 1.9 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus Sdh_cyt PF01127.17 KFX95882.1 - 3.2 7.6 6.5 6.2 6.6 4.5 1.4 1 1 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit NAD_kinase PF01513.16 KFX95885.1 - 1.9e-68 230.2 0.0 2.6e-68 229.8 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase RNase_PH PF01138.16 KFX95886.1 - 4e-14 53.0 0.4 6.2e-14 52.4 0.3 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 PTPA PF03095.10 KFX95887.1 - 1.2e-112 375.9 0.0 1.5e-112 375.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein FAA_hydrolase PF01557.13 KFX95888.1 - 6.6e-61 205.5 0.0 8.7e-61 205.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Complex1_LYR PF05347.10 KFX95889.1 - 1e-16 60.4 1.9 1.3e-16 60.1 1.3 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFX95889.1 - 1.2e-13 51.0 2.5 1.3e-13 50.8 1.8 1.1 1 0 0 1 1 1 1 Complex1_LYR-like RhoGAP PF00620.22 KFX95891.1 - 1.9e-42 144.4 0.1 4.4e-42 143.2 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 KFX95891.1 - 1.3e-11 44.6 0.0 3e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFX95891.1 - 4.7e-09 36.4 0.4 1.5e-08 34.8 0.0 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PX PF00787.19 KFX95891.1 - 0.0084 15.8 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 PX domain PH_8 PF15409.1 KFX95891.1 - 0.017 15.1 0.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain PH_7 PF15408.1 KFX95891.1 - 0.27 11.1 0.0 0.51 10.2 0.0 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain TPR_12 PF13424.1 KFX95907.1 - 2.3e-11 43.4 32.5 0.061 13.2 0.4 10.6 11 1 0 11 11 10 4 Tetratricopeptide repeat AAA_22 PF13401.1 KFX95907.1 - 1.7e-08 34.6 2.6 5.6e-08 32.9 0.1 3.3 2 1 0 2 2 2 1 AAA domain TPR_14 PF13428.1 KFX95907.1 - 4.4e-07 29.9 0.5 17 6.3 0.0 8.8 9 1 1 10 10 9 0 Tetratricopeptide repeat AAA_16 PF13191.1 KFX95907.1 - 1.7e-06 28.1 0.1 7.1e-06 26.1 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain TPR_10 PF13374.1 KFX95907.1 - 0.0011 18.8 3.3 1.9 8.5 0.0 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFX95907.1 - 0.0018 18.5 18.9 0.082 13.2 0.1 8.2 10 0 0 10 10 8 1 Tetratricopeptide repeat DUF3137 PF11335.3 KFX95907.1 - 0.0025 17.4 0.1 0.013 15.2 0.0 2.3 2 0 0 2 2 1 1 Protein of unknown function (DUF3137) TPR_7 PF13176.1 KFX95907.1 - 0.0033 17.1 18.2 2.7 8.0 0.1 9.1 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFX95907.1 - 0.0068 16.2 18.8 8 6.6 0.1 8.6 9 0 0 9 9 8 1 Tetratricopeptide repeat AAA_19 PF13245.1 KFX95907.1 - 0.099 12.4 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain TPR_6 PF13174.1 KFX95907.1 - 0.29 11.6 8.3 62 4.3 0.1 6.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFX95907.1 - 1.1 8.9 13.6 6.6 6.5 0.1 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFX95907.1 - 3 7.8 24.2 0.13 12.0 0.2 7.7 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFX95907.1 - 6 6.5 15.1 17 5.1 0.1 5.8 5 2 2 7 7 6 0 TPR repeat Thiolase_C PF02803.13 KFX95908.1 - 2.8e-12 46.1 2.5 6.5e-11 41.7 0.0 2.7 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KFX95908.1 - 3.8e-06 26.4 0.1 0.0003 20.3 0.0 2.7 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 KFX95908.1 - 7.1e-05 21.9 0.0 0.00033 19.7 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 KFX95908.1 - 0.0013 18.3 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 KFX95908.1 - 0.031 14.1 0.3 3.3 7.5 0.0 2.6 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain DAO PF01266.19 KFX95909.1 - 5.9e-51 173.4 0.0 9.7e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFX95909.1 - 6.3e-09 35.1 0.8 2.2e-08 33.4 0.5 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KFX95909.1 - 3.2e-07 29.7 0.0 1.1e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFX95909.1 - 4.2e-05 23.5 0.1 0.00032 20.6 0.0 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX95909.1 - 0.0019 18.1 0.1 0.0053 16.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFX95909.1 - 0.006 16.9 0.3 0.024 15.0 0.3 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFX95909.1 - 0.018 13.5 0.2 0.032 12.7 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 KFX95909.1 - 0.04 13.5 0.7 0.066 12.8 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KFX95909.1 - 0.051 12.6 0.0 0.22 10.5 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 KFX95909.1 - 0.054 12.3 0.3 0.26 10.1 0.2 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 KFX95909.1 - 0.066 12.2 0.2 0.22 10.6 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 KFX95909.1 - 0.085 11.7 0.1 0.29 9.9 0.2 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein PPR_2 PF13041.1 KFX95910.1 - 6.3e-21 74.0 0.1 3.2e-08 33.4 0.0 6.9 6 2 2 8 8 8 4 PPR repeat family PPR PF01535.15 KFX95910.1 - 4.3e-12 45.1 0.1 0.0059 16.5 0.0 5.8 6 0 0 6 6 6 3 PPR repeat PPR_3 PF13812.1 KFX95910.1 - 7.8e-11 41.3 0.2 0.00066 19.7 0.0 5.4 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 KFX95910.1 - 1.5e-08 33.9 0.0 0.12 11.8 0.0 5.0 5 0 0 5 5 5 2 PPR repeat TPR_14 PF13428.1 KFX95910.1 - 0.11 13.2 0.0 59 4.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat cwf18 PF08315.7 KFX95911.1 - 1.6e-43 148.2 4.3 1.6e-43 148.2 3.0 1.8 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor zf-CCHC_3 PF13917.1 KFX95912.1 - 1.8e-20 72.4 1.6 4.1e-20 71.2 1.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 KFX95912.1 - 0.00083 18.7 0.3 0.0018 17.7 0.2 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.18 KFX95912.1 - 0.0046 16.8 1.3 0.0074 16.1 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 KFX95912.1 - 0.12 11.8 0.6 0.34 10.4 0.4 1.8 1 0 0 1 1 1 0 Zinc knuckle SUZ PF12752.2 KFX95913.1 - 3.4e-17 62.6 1.3 3.4e-17 62.6 0.9 2.6 3 0 0 3 3 3 1 SUZ domain R3H PF01424.17 KFX95913.1 - 5.5e-09 35.5 0.0 1.2e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 R3H domain Ribosomal_L17 PF01196.14 KFX95914.1 - 1.1e-32 112.4 0.0 2.2e-32 111.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L17 DUF3552 PF12072.3 KFX95914.1 - 0.54 9.4 3.8 0.93 8.6 0.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3552) Zn_clus PF00172.13 KFX95917.1 - 6.6e-06 25.9 9.2 1.3e-05 24.9 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX95917.1 - 0.008 15.0 0.1 0.017 14.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2039 PF10217.4 KFX95917.1 - 0.34 10.9 5.0 0.4 10.7 1.9 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) adh_short PF00106.20 KFX95918.1 - 4e-08 33.3 0.2 4.4e-08 33.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KFX95918.1 - 2.5e-05 23.8 0.0 2.7e-05 23.7 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KFX95918.1 - 0.00019 21.2 0.1 0.00022 21.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KFX95918.1 - 0.0015 18.5 0.1 0.0015 18.5 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KFX95918.1 - 0.0051 16.5 0.1 0.0055 16.3 0.1 1.1 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 KFX95918.1 - 0.075 11.9 0.1 0.083 11.7 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain MFS_1 PF07690.11 KFX95922.1 - 1.3e-46 158.9 32.1 1.7e-46 158.5 22.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX95922.1 - 2e-12 46.4 12.2 2e-12 46.4 8.4 1.7 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KFX95922.1 - 0.00028 19.2 4.5 0.00042 18.6 3.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 KFX95922.1 - 6.1 4.7 10.7 42 2.0 5.5 2.8 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Metal_hydrol PF10118.4 KFX95922.1 - 9.9 5.5 6.6 26 4.1 0.4 2.3 1 1 1 2 2 2 0 Predicted metal-dependent hydrolase SnoaL_4 PF13577.1 KFX95923.1 - 4.3e-20 71.9 0.0 5.3e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 KFX95923.1 - 2.5e-05 24.4 0.0 6.2e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) Lumazine_bd_2 PF12893.2 KFX95923.1 - 0.00025 21.5 0.0 0.00041 20.8 0.0 1.3 1 0 0 1 1 1 1 Putative lumazine-binding Ring_hydroxyl_B PF00866.13 KFX95923.1 - 0.049 13.3 0.0 0.1 12.2 0.0 1.5 1 1 1 2 2 2 0 Ring hydroxylating beta subunit SnoaL_3 PF13474.1 KFX95923.1 - 0.11 12.5 0.0 0.4 10.7 0.0 1.9 1 1 0 1 1 1 0 SnoaL-like domain MFS_1 PF07690.11 KFX95926.1 - 3.2e-18 65.5 67.3 1.9e-15 56.4 28.6 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFX95926.1 - 1.7e-09 36.4 24.7 3.9e-09 35.2 17.0 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ferric_reduct PF01794.14 KFX95927.1 - 2.9e-13 50.0 10.4 6.7e-13 48.8 7.2 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KFX95927.1 - 5.6e-08 32.8 0.1 0.01 15.7 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFX95927.1 - 5.9e-06 26.0 0.0 0.0004 20.2 0.0 2.5 2 0 0 2 2 2 1 FAD-binding domain DUF2183 PF09949.4 KFX95928.1 - 6.5e-17 61.3 0.1 1.1e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Peptidase_C12 PF01088.16 KFX95929.1 - 4.4e-60 202.5 0.0 5.2e-60 202.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 adh_short PF00106.20 KFX95930.1 - 1.2e-28 100.1 4.3 2e-28 99.4 3.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX95930.1 - 2.5e-27 96.1 0.0 3.2e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX95930.1 - 1.2e-15 57.7 2.7 1.4e-15 57.4 1.2 1.6 2 0 0 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.14 KFX95930.1 - 0.094 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NOSIC PF08060.8 KFX95936.1 - 5.4e-22 77.3 0.1 1.3e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain Nop PF01798.13 KFX95936.1 - 2.9e-15 55.8 0.0 5.2e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain Acetate_kinase PF00871.12 KFX95937.1 - 9e-84 281.2 0.1 7.4e-65 218.9 0.0 2.0 1 1 1 2 2 2 2 Acetokinase family GST_N_3 PF13417.1 KFX95938.1 - 1.4e-19 70.0 0.3 3.4e-19 68.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFX95938.1 - 2.2e-11 43.5 0.7 5.6e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFX95938.1 - 4.6e-05 23.2 0.2 0.00012 21.8 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HAT PF02184.11 KFX95939.1 - 4.4e-26 90.3 67.8 2.7e-12 46.2 1.1 14.1 15 0 0 15 15 15 6 HAT (Half-A-TPR) repeat TPR_19 PF14559.1 KFX95939.1 - 9.2e-21 73.9 2.2 1.9e-05 24.8 0.0 7.1 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 KFX95939.1 - 1.1e-20 72.2 27.3 0.0024 18.3 0.1 11.9 6 3 7 13 13 13 6 Tetratricopeptide repeat TPR_16 PF13432.1 KFX95939.1 - 7e-20 71.1 16.5 0.03 14.9 0.0 8.7 9 1 1 10 10 10 7 Tetratricopeptide repeat Suf PF05843.9 KFX95939.1 - 7.6e-12 45.5 21.5 6.9e-05 22.7 0.7 6.0 2 1 4 6 6 6 3 Suppressor of forked protein (Suf) TPR_2 PF07719.12 KFX95939.1 - 1.6e-11 43.1 19.2 0.45 10.5 0.0 10.5 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFX95939.1 - 2.2e-09 36.8 6.2 0.049 13.2 0.2 6.6 5 2 2 7 7 7 2 TPR repeat U3_assoc_6 PF08640.6 KFX95939.1 - 9.1e-08 31.7 22.5 0.014 15.1 0.9 6.8 4 2 2 6 6 6 3 U3 small nucleolar RNA-associated protein 6 TPR_12 PF13424.1 KFX95939.1 - 5.1e-05 23.1 26.7 0.23 11.4 0.0 8.9 9 2 1 10 10 10 3 Tetratricopeptide repeat TPR_15 PF13429.1 KFX95939.1 - 0.00049 19.2 18.4 0.016 14.2 1.3 5.0 1 1 5 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFX95939.1 - 0.00057 19.8 7.8 0.048 13.8 0.1 5.3 7 0 0 7 7 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFX95939.1 - 0.0038 16.9 14.1 6 6.9 0.0 7.6 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFX95939.1 - 0.0051 16.4 6.6 35 4.4 0.0 7.0 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFX95939.1 - 0.014 15.8 20.0 6.9 7.3 0.0 9.1 10 0 0 10 10 10 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFX95939.1 - 0.066 13.1 9.7 20 5.1 0.5 5.8 7 0 0 7 7 6 0 Fis1 C-terminal tetratricopeptide repeat NRDE-2 PF08424.5 KFX95939.1 - 0.18 10.6 27.0 0.31 9.8 2.5 6.2 3 3 4 7 7 7 0 NRDE-2, necessary for RNA interference PBP1_TM PF14812.1 KFX95939.1 - 6.2 7.2 16.2 0.054 13.7 2.0 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HMG_box PF00505.14 KFX95940.1 - 3.6e-13 49.5 2.2 4.6e-09 36.4 0.2 3.5 3 1 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 KFX95940.1 - 6.8e-11 42.3 0.9 5e-07 29.9 0.0 3.2 3 0 0 3 3 3 2 HMG-box domain Carb_anhydrase PF00194.16 KFX95976.1 - 5.9e-18 64.7 0.2 5.7e-10 38.5 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Sugar_tr PF00083.19 KFX95977.1 - 3.2e-64 217.1 30.2 3.9e-64 216.8 20.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX95977.1 - 1.2e-19 70.2 45.9 1.8e-12 46.6 17.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily PIG-L PF02585.12 KFX95979.1 - 2.2e-24 86.4 0.0 3.5e-24 85.7 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase DUF4355 PF14265.1 KFX95980.1 - 0.0035 17.2 0.6 0.0055 16.6 0.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4355) Epiglycanin_C PF14654.1 KFX95980.1 - 0.11 12.5 1.5 0.22 11.5 1.1 1.5 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Peptidase_S8 PF00082.17 KFX95992.1 - 7.8e-08 31.7 1.8 7.8e-08 31.7 1.3 1.0 1 0 0 1 1 1 1 Subtilase family LexA_DNA_bind PF01726.11 KFX95992.1 - 0.0077 15.7 0.0 0.0083 15.6 0.0 1.2 1 0 0 1 1 1 1 LexA DNA binding domain Transferase PF02458.10 KFX95994.1 - 9.9e-24 83.5 0.0 2.8e-22 78.7 0.0 2.0 2 0 0 2 2 2 2 Transferase family Transferase PF02458.10 KFX95995.1 - 1.5e-16 59.8 0.0 3.3e-10 39.0 0.0 2.8 2 1 0 2 2 2 2 Transferase family Chalcone PF02431.10 KFX95995.1 - 0.15 11.4 0.0 0.53 9.6 0.0 1.8 2 0 0 2 2 2 0 Chalcone-flavanone isomerase DUF2293 PF10056.4 KFX96017.1 - 1.3e-25 89.1 0.1 2.8e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) AAA PF00004.24 KFX96018.1 - 4.2e-47 159.6 0.0 5.6e-47 159.2 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFX96018.1 - 1.2e-06 28.6 0.1 2e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KFX96018.1 - 2.7e-06 26.6 0.0 5.5e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KFX96018.1 - 5e-06 26.6 0.0 0.00062 19.9 0.0 2.5 2 1 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 KFX96018.1 - 7.8e-05 21.8 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_2 PF07724.9 KFX96018.1 - 0.0001 22.2 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KFX96018.1 - 0.00017 21.3 0.1 0.0014 18.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KFX96018.1 - 0.00022 21.1 0.0 0.00032 20.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFX96018.1 - 0.00043 20.1 0.0 0.001 18.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFX96018.1 - 0.0008 19.1 0.6 0.006 16.3 0.1 2.6 2 1 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 KFX96018.1 - 0.00084 18.7 0.5 0.77 9.1 0.2 2.3 1 1 0 2 2 2 2 AAA domain NACHT PF05729.7 KFX96018.1 - 0.0012 18.4 0.1 0.11 12.1 0.0 2.2 1 1 1 2 2 2 1 NACHT domain Mg_chelatase PF01078.16 KFX96018.1 - 0.0021 17.2 0.1 0.0089 15.2 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 KFX96018.1 - 0.0024 18.6 0.0 0.0043 17.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KFX96018.1 - 0.0034 16.3 0.0 0.0048 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 KFX96018.1 - 0.0035 16.7 0.1 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KFX96018.1 - 0.0041 15.8 0.0 0.0057 15.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus Sigma54_activat PF00158.21 KFX96018.1 - 0.0083 15.6 0.0 0.04 13.3 0.0 1.9 1 1 1 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KFX96018.1 - 0.0089 16.0 0.0 0.017 15.2 0.0 1.5 1 1 0 1 1 1 1 Sigma-54 interaction domain RNA_helicase PF00910.17 KFX96018.1 - 0.012 15.7 0.0 0.02 15.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 KFX96018.1 - 0.013 15.7 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_3 PF07726.6 KFX96018.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KFX96018.1 - 0.015 15.0 0.0 0.15 11.7 0.0 2.0 1 1 1 2 2 2 0 Archaeal ATPase AAA_28 PF13521.1 KFX96018.1 - 0.018 14.9 0.0 0.041 13.8 0.0 1.6 2 0 0 2 2 1 0 AAA domain ATP-synt_ab PF00006.20 KFX96018.1 - 0.029 13.8 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Viral_helicase1 PF01443.13 KFX96018.1 - 0.038 13.4 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 KFX96018.1 - 0.039 14.2 0.0 0.068 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KFX96018.1 - 0.04 12.7 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Cytidylate_kin2 PF13189.1 KFX96018.1 - 0.067 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family Bac_DnaA PF00308.13 KFX96018.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.7 1 1 0 1 1 1 0 Bacterial dnaA protein SKI PF01202.17 KFX96018.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase AAA_24 PF13479.1 KFX96018.1 - 0.17 11.4 0.1 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KFX96018.1 - 0.18 11.0 0.1 0.29 10.3 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein Rad17 PF03215.10 KFX96018.1 - 0.2 10.3 0.0 0.26 9.9 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein NmrA PF05368.8 KFX96024.1 - 0.016 14.4 0.0 0.02 14.1 0.0 1.1 1 0 0 1 1 1 0 NmrA-like family Band_7 PF01145.20 KFX96025.1 - 3.7e-26 92.1 3.6 6.2e-26 91.3 2.5 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family UcrQ PF02939.11 KFX96026.1 - 4.7e-31 106.4 0.3 5.7e-31 106.1 0.2 1.1 1 0 0 1 1 1 1 UcrQ family Nucleopor_Nup85 PF07575.8 KFX96027.1 - 3.2e-15 55.3 1.6 3.3e-07 28.9 1.3 3.9 2 1 0 2 2 2 2 Nup85 Nucleoporin Smg4_UPF3 PF03467.10 KFX96029.1 - 2.7e-26 92.6 0.0 1.8e-25 89.9 0.0 2.2 1 1 0 1 1 1 1 Smg-4/UPF3 family SRP-alpha_N PF04086.8 KFX96029.1 - 2.4 7.4 14.1 3.3 7.0 9.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2413 PF10310.4 KFX96029.1 - 3.2 6.4 16.3 1.1 8.0 9.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2413) Metallophos PF00149.23 KFX96030.1 - 4.3e-37 127.4 0.0 4.9e-32 110.9 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase DUF4600 PF15372.1 KFX96032.1 - 0.039 14.1 0.9 0.051 13.7 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) DUF663 PF04950.7 KFX96033.1 - 9e-104 346.5 0.0 1.3e-103 346.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KFX96033.1 - 5.9e-19 67.3 0.0 1.4e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain FA_desaturase PF00487.19 KFX96034.1 - 2.1e-31 109.2 11.5 3.2e-31 108.7 8.0 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 KFX96034.1 - 2.9e-19 67.9 0.5 5.4e-19 67.1 0.3 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Motile_Sperm PF00635.21 KFX96035.1 - 5.1e-25 87.2 0.2 8.7e-25 86.4 0.1 1.4 1 1 0 1 1 1 1 MSP (Major sperm protein) domain DUF2077 PF09850.4 KFX96035.1 - 0.066 12.6 0.3 0.23 10.8 0.1 2.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) UBX PF00789.15 KFX96036.1 - 2.8e-05 24.0 0.0 8.2e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 UBX domain UBA PF00627.26 KFX96036.1 - 0.0039 16.9 0.0 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain zf-C2H2_2 PF12756.2 KFX96036.1 - 0.016 15.2 0.1 0.035 14.2 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KFX96036.1 - 0.059 13.7 0.3 0.1 12.9 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type UBA_2 PF08587.6 KFX96036.1 - 0.066 13.4 0.5 0.58 10.3 0.0 2.6 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) zf-C2H2_jaz PF12171.3 KFX96036.1 - 0.15 12.2 0.3 0.26 11.4 0.2 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding CpXC PF14353.1 KFX96036.1 - 0.29 11.1 7.5 0.31 10.9 4.2 1.8 1 1 0 1 1 1 0 CpXC protein APG6 PF04111.7 KFX96036.1 - 0.85 8.6 20.0 1.7 7.6 13.9 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3723 PF12520.3 KFX96040.1 - 1.7e-95 320.4 0.8 1.3e-93 314.2 0.6 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3723) Pkinase_Tyr PF07714.12 KFX96041.1 - 1.5e-05 24.2 0.0 2.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KFX96041.1 - 2.2e-05 23.7 0.0 6.9e-05 22.1 0.0 1.8 3 0 0 3 3 3 1 Protein kinase domain F-box-like PF12937.2 KFX96043.1 - 0.0026 17.4 0.0 0.008 15.8 0.0 1.9 1 0 0 1 1 1 1 F-box-like Phage_Coat_B PF05356.6 KFX96043.1 - 0.12 12.1 6.8 12 5.6 0.0 4.1 1 1 3 4 4 4 0 Phage Coat protein B Bactofilin PF04519.8 KFX96043.1 - 0.15 12.0 2.8 5.7 7.0 1.0 3.0 1 1 1 2 2 2 0 Polymer-forming cytoskeletal DUF4164 PF13747.1 KFX96045.1 - 0.032 14.3 2.2 0.039 14.0 0.8 1.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4164) Pkinase PF00069.20 KFX96046.1 - 3.7e-10 39.4 0.1 5.5e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX96046.1 - 4.9e-06 25.7 0.1 8.2e-06 25.0 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_2 PF07719.12 KFX96047.1 - 0.0078 16.0 2.1 0.35 10.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFX96047.1 - 0.04 14.5 0.1 13 6.7 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFX96047.1 - 0.05 13.5 0.9 0.25 11.3 0.0 2.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Acetyltransf_7 PF13508.1 KFX96048.1 - 0.0087 16.1 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX96048.1 - 0.017 15.1 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FAM70 PF14967.1 KFX96063.1 - 9.1 5.3 8.3 9.8 5.2 5.8 1.0 1 0 0 1 1 1 0 FAM70 protein Glyco_hyd_65N_2 PF14498.1 KFX96066.1 - 3e-49 167.8 0.0 4.8e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain DUF2418 PF10332.4 KFX96067.1 - 0.13 12.6 0.5 0.19 12.0 0.0 1.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2418) Pyridoxal_deC PF00282.14 KFX96068.1 - 5.1e-16 58.0 0.0 7.5e-16 57.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KFX96068.1 - 0.0035 16.1 0.0 0.0066 15.2 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Resolvase PF00239.16 KFX96068.1 - 0.13 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Resolvase, N terminal domain Glyco_transf_34 PF05637.7 KFX96069.1 - 1.7e-73 247.0 0.0 2e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 KFX96069.1 - 0.00071 18.9 0.0 0.13 11.5 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function, DUF273 PMI_typeI PF01238.16 KFX96070.1 - 7e-66 222.7 0.0 5.4e-65 219.7 0.0 1.9 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 KFX96070.1 - 0.0021 17.4 0.2 1.7 8.2 0.2 2.6 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 KFX96070.1 - 0.15 11.7 0.1 0.62 9.7 0.0 1.9 2 0 0 2 2 2 0 AraC-like ligand binding domain AMP-binding PF00501.23 KFX96072.1 - 4.1e-87 292.2 0.0 5.2e-87 291.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX96072.1 - 8e-15 55.5 0.0 2.2e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 KFX96072.1 - 0.0028 16.2 0.0 0.011 14.2 0.0 1.8 2 0 0 2 2 2 1 GH3 auxin-responsive promoter NAD_binding_2 PF03446.10 KFX96073.1 - 1.8e-26 92.9 0.0 3.1e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KFX96073.1 - 2.5e-09 37.2 0.1 4.9e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KFX96073.1 - 2.7e-08 34.1 0.1 7.5e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KFX96073.1 - 2.4e-06 27.6 0.0 4.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Glyco_hydro_61 PF03443.9 KFX96074.1 - 1.4e-54 185.2 0.0 2e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Sugar_tr PF00083.19 KFX96075.1 - 2.9e-77 260.1 16.4 3.4e-77 259.9 11.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX96075.1 - 2.2e-18 66.0 22.8 2.2e-18 66.0 15.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.13 KFX96076.1 - 7.6e-09 35.3 8.4 1.3e-08 34.5 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX96076.1 - 0.0016 17.3 0.2 0.0031 16.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.16 KFX96077.1 - 1.7e-85 286.5 0.0 2.6e-85 285.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFX96077.1 - 1.7e-69 233.8 0.0 6.9e-69 231.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFX96077.1 - 3.6e-20 71.6 1.0 8.5e-20 70.4 0.4 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 KFX96077.1 - 5e-14 52.1 0.2 9.9e-14 51.2 0.1 1.4 1 0 0 1 1 1 1 PA14 domain CARDB PF07705.6 KFX96077.1 - 0.093 12.7 0.3 0.8 9.7 0.0 2.2 2 0 0 2 2 2 0 CARDB Pkinase PF00069.20 KFX96078.1 - 9.6e-61 205.1 0.4 1.1e-60 204.9 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX96078.1 - 4.1e-21 75.2 0.0 6.2e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFX96078.1 - 2e-07 30.9 0.0 6.4e-05 22.8 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 KFX96078.1 - 0.0038 16.2 0.0 0.0069 15.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 KFX96078.1 - 0.0057 16.2 0.1 0.025 14.1 0.0 2.0 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 KFX96078.1 - 0.038 13.0 0.3 0.095 11.7 0.2 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF257 PF03192.8 KFX96078.1 - 0.07 12.4 0.8 2.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Pyrococcus protein of unknown function, DUF257 YrbL-PhoP_reg PF10707.4 KFX96078.1 - 0.076 12.3 0.5 1.3 8.3 0.0 2.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL RNase_P_p30 PF01876.11 KFX96079.1 - 1.8e-45 153.8 0.0 2.6e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 Adenosine_kin PF04008.9 KFX96079.1 - 0.14 11.6 0.1 0.28 10.6 0.1 1.4 1 0 0 1 1 1 0 Adenosine specific kinase P22_Tail-4 PF11650.3 KFX96080.1 - 0.0064 16.0 0.4 0.015 14.8 0.3 1.6 1 0 0 1 1 1 1 P22 tail accessory factor TFIIS_M PF07500.9 KFX96081.1 - 5.5e-27 94.1 1.8 7.6e-27 93.6 0.2 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 KFX96081.1 - 3.3e-18 65.0 6.0 5.3e-18 64.3 4.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 KFX96081.1 - 2.1e-13 49.5 0.2 5.3e-13 48.2 0.2 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Med16 PF11635.3 KFX96081.1 - 0.079 10.9 1.2 0.099 10.5 0.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 PALP PF00291.20 KFX96082.1 - 2.1e-55 188.1 0.8 2.5e-55 187.8 0.6 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.12 KFX96083.1 - 8e-38 130.2 0.0 1.4e-37 129.5 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.11 KFX96083.1 - 0.00079 18.4 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase GrpB PF04229.9 KFX96084.1 - 8.3e-37 126.4 0.1 1e-36 126.1 0.1 1.0 1 0 0 1 1 1 1 GrpB protein tRNA-synt_2c PF01411.14 KFX96085.1 - 4.5e-186 619.4 0.8 4.5e-186 619.4 0.6 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KFX96085.1 - 1.8e-17 62.9 0.3 3.9e-17 61.8 0.2 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 KFX96085.1 - 2e-05 24.1 0.9 7.1e-05 22.4 0.7 2.0 1 0 0 1 1 1 1 DHHA1 domain XPC-binding PF09280.6 KFX96085.1 - 0.081 12.3 0.3 0.2 11.1 0.2 1.7 1 0 0 1 1 1 0 XPC-binding domain Pro_isomerase PF00160.16 KFX96089.1 - 1.9e-39 135.3 0.6 2.4e-39 135.0 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD adh_short PF00106.20 KFX96090.1 - 8.6e-22 77.8 1.4 1.1e-21 77.4 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX96090.1 - 8.3e-13 48.3 0.1 1.3e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFX96090.1 - 4.8e-08 33.0 0.1 6.6e-08 32.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 KFX96090.1 - 9e-05 21.5 0.0 0.00011 21.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KFX96090.1 - 0.00016 21.1 0.3 0.00035 20.0 0.2 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.8 KFX96090.1 - 0.064 12.6 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family Pro_isomerase PF00160.16 KFX96091.1 - 1.2e-47 162.0 0.0 2.6e-47 160.9 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 KFX96091.1 - 0.00019 21.3 0.1 0.00054 19.8 0.0 1.7 2 0 0 2 2 2 1 U-box domain Tetrabrachion PF11401.3 KFX96091.1 - 0.13 12.1 0.3 5.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Tetrabrachion YjeF_N PF03853.10 KFX96092.1 - 1.6e-32 112.4 0.0 2e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus DUF2795 PF11387.3 KFX96092.1 - 0.083 12.7 0.0 8.7 6.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2795) Fungal_trans_2 PF11951.3 KFX96093.1 - 1e-07 30.9 0.3 1.5e-07 30.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain HMGL-like PF00682.14 KFX96096.1 - 6e-62 209.4 0.2 1.1e-61 208.5 0.1 1.4 1 0 0 1 1 1 1 HMGL-like DAO PF01266.19 KFX96098.1 - 2.3e-51 174.7 0.0 2.9e-51 174.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KFX96098.1 - 1.6e-05 24.7 0.0 0.0047 16.7 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KFX96098.1 - 0.018 15.0 0.1 0.039 13.9 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KFX96098.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein adh_short PF00106.20 KFX96099.1 - 3.2e-19 69.4 0.0 1.8e-15 57.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase NAD_binding_10 PF13460.1 KFX96099.1 - 3.8e-13 49.8 0.2 4.6e-11 43.0 0.0 2.7 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KFX96099.1 - 1.2e-12 47.7 0.0 4.2e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KFX96099.1 - 4.4e-10 39.2 0.0 1.4e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 KFX96099.1 - 2e-09 37.3 0.0 4.7e-06 26.3 0.0 2.3 2 0 0 2 2 2 2 KR domain 3Beta_HSD PF01073.14 KFX96099.1 - 2.4e-05 23.1 0.0 0.00012 20.8 0.0 2.0 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KFX96099.1 - 0.00016 20.7 0.0 0.039 12.8 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.7 KFX96099.1 - 0.00025 20.0 0.0 0.058 12.3 0.0 2.9 2 1 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 KFX96099.1 - 0.00064 18.7 0.0 0.4 9.5 0.0 2.9 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein DapB_N PF01113.15 KFX96099.1 - 0.00083 19.2 0.0 0.0033 17.3 0.0 2.0 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus adh_short_C2 PF13561.1 KFX96099.1 - 0.0028 17.4 0.0 0.0054 16.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Semialdhyde_dh PF01118.19 KFX96099.1 - 0.0066 16.7 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 KFX96099.1 - 0.018 15.0 0.0 0.053 13.5 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain zf-C2H2_4 PF13894.1 KFX96119.1 - 6.3e-07 29.2 13.1 0.0012 19.0 1.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KFX96119.1 - 2.6e-05 24.2 12.9 0.067 13.5 1.5 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFX96119.1 - 0.00029 20.9 11.0 0.25 11.7 0.4 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-Di19 PF05605.7 KFX96119.1 - 0.055 13.5 6.5 0.13 12.3 0.5 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Nuc_sug_transp PF04142.10 KFX96120.1 - 5.8e-07 28.8 3.4 1e-06 28.0 2.4 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 KFX96120.1 - 0.0033 17.0 10.8 0.031 13.9 0.1 3.0 2 2 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 KFX96120.1 - 0.0034 17.4 23.7 0.0079 16.2 3.2 3.3 2 1 1 3 3 3 3 EamA-like transporter family S-methyl_trans PF02574.11 KFX96120.1 - 0.062 12.5 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Homocysteine S-methyltransferase DUF2985 PF11204.3 KFX96121.1 - 1.2e-38 130.6 1.6 2.2e-38 129.8 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Sen15 PF09631.5 KFX96122.1 - 1.3e-26 92.7 0.0 2.3e-26 91.9 0.0 1.4 1 1 0 1 1 1 1 Sen15 protein ADH_N PF08240.7 KFX96123.1 - 9.4e-30 102.5 0.4 1.7e-29 101.7 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX96123.1 - 2.6e-25 88.4 0.0 4.1e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KFX96123.1 - 0.0054 16.3 0.1 0.011 15.3 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.16 KFX96123.1 - 0.039 13.5 0.1 0.076 12.5 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 KFX96123.1 - 0.14 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Yippee-Mis18 PF03226.9 KFX96124.1 - 5.6e-22 77.6 1.1 6.4e-22 77.4 0.8 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-CHY PF05495.7 KFX96124.1 - 0.017 15.2 1.2 3.9 7.7 0.1 2.2 2 0 0 2 2 2 0 CHY zinc finger DUF2039 PF10217.4 KFX96124.1 - 0.046 13.7 1.1 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) GFA PF04828.9 KFX96124.1 - 0.052 13.4 1.5 1.1 9.2 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF3268 PF11672.3 KFX96124.1 - 0.069 13.2 2.0 0.72 9.9 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3268) Endonuclease_7 PF02945.10 KFX96124.1 - 0.098 12.3 1.4 0.37 10.5 1.0 2.0 1 1 0 1 1 1 0 Recombination endonuclease VII DZR PF12773.2 KFX96124.1 - 0.11 12.3 1.2 0.6 9.9 0.8 1.9 1 1 0 1 1 1 0 Double zinc ribbon Mcm10 PF09332.6 KFX96124.1 - 0.16 11.3 1.1 0.21 10.8 0.7 1.3 1 1 0 1 1 1 0 Mcm10 replication factor Evr1_Alr PF04777.8 KFX96124.1 - 0.23 11.3 1.7 1 9.2 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family Ferric_reduct PF01794.14 KFX96126.1 - 2.8e-20 72.6 12.2 5.6e-20 71.6 6.4 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KFX96126.1 - 1.5e-19 70.4 0.0 4.7e-11 42.8 0.0 2.5 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFX96126.1 - 5.9e-14 51.8 0.0 1.8e-13 50.2 0.0 1.8 1 1 0 1 1 1 1 FAD-binding domain Baculo_11_kDa PF06143.6 KFX96126.1 - 0.0045 16.3 0.1 0.013 14.8 0.0 1.8 1 0 0 1 1 1 1 Baculovirus 11 kDa family DUF3754 PF12576.3 KFX96126.1 - 0.43 10.2 5.1 1.1 8.9 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) SH3_3 PF08239.6 KFX96132.1 - 0.00029 20.9 0.1 0.00051 20.1 0.1 1.3 1 0 0 1 1 1 1 Bacterial SH3 domain HATPase_c PF02518.21 KFX96135.1 - 2.5e-26 91.5 0.0 7.9e-26 89.9 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KFX96135.1 - 4.6e-26 91.0 0.2 8.3e-26 90.1 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KFX96135.1 - 2.2e-13 49.9 0.0 5.2e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 KFX96135.1 - 0.047 13.8 6.0 0.1 12.7 0.0 2.9 3 0 0 3 3 3 0 HAMP domain Syja_N PF02383.13 KFX96137.1 - 4.9e-95 317.9 0.0 7.1e-95 317.4 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 KFX96137.1 - 1.3e-29 101.8 0.0 2.3e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase DUF3115 PF11312.3 KFX96138.1 - 3.9e-84 282.2 0.0 4.6e-84 281.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) zf-C2H2_4 PF13894.1 KFX96139.1 - 1.5e-05 24.9 12.7 0.37 11.2 0.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KFX96139.1 - 0.00044 20.4 13.9 0.41 11.0 2.8 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type APG6 PF04111.7 KFX96139.1 - 0.018 14.0 10.6 0.026 13.5 7.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-H2C2_2 PF13465.1 KFX96139.1 - 0.033 14.4 18.5 1.2 9.5 0.4 3.7 3 0 0 3 3 3 0 Zinc-finger double domain FlxA PF14282.1 KFX96139.1 - 0.49 10.3 14.5 0.91 9.4 10.0 1.4 1 0 0 1 1 1 0 FlxA-like protein V_ATPase_I PF01496.14 KFX96139.1 - 1.6 6.4 5.7 2 6.1 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ADIP PF11559.3 KFX96139.1 - 2.4 8.0 13.9 4.8 7.0 9.6 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding LRR_6 PF13516.1 KFX96143.1 - 0.00012 21.7 0.7 2.4 8.5 0.0 4.1 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.2 KFX96143.1 - 0.024 14.2 4.6 1.4 8.6 0.0 4.0 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KFX96143.1 - 0.049 13.6 2.1 5.5 7.4 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 KFX96143.1 - 0.18 12.1 2.0 35 5.2 0.1 4.2 3 0 0 3 3 3 0 Leucine rich repeat DUF3306 PF11748.3 KFX96143.1 - 0.35 11.5 0.0 0.35 11.5 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3306) LRR_8 PF13855.1 KFX96143.1 - 1.5 8.6 5.1 0.8 9.5 0.1 3.1 3 0 0 3 3 3 0 Leucine rich repeat MFS_1 PF07690.11 KFX96147.1 - 3.4e-14 52.3 38.9 1.2e-13 50.5 27.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2208 PF09973.4 KFX96147.1 - 0.055 12.7 0.0 0.18 11.0 0.0 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Asp PF00026.18 KFX96148.1 - 0.00028 20.2 0.0 0.49 9.5 0.0 2.3 2 0 0 2 2 2 2 Eukaryotic aspartyl protease Adeno_E3_CR2 PF02439.10 KFX96148.1 - 0.00043 19.7 0.3 0.00081 18.8 0.2 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Herpes_gE PF02480.11 KFX96149.1 - 0.0087 14.3 0.0 0.014 13.6 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 KFX96149.1 - 0.085 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF1517 PF07466.6 KFX96149.1 - 0.18 10.7 1.0 0.29 10.0 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) zf-C2H2_2 PF12756.2 KFX96150.1 - 1.2e-31 108.7 9.0 5.5e-23 81.0 2.1 3.5 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KFX96150.1 - 2.6e-05 24.2 0.3 2.6e-05 24.2 0.2 3.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFX96150.1 - 0.0023 18.0 10.1 0.1 12.8 0.3 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type F-box-like PF12937.2 KFX96150.1 - 0.0041 16.8 0.4 0.012 15.3 0.3 1.9 1 1 0 1 1 1 1 F-box-like zf-C2H2_6 PF13912.1 KFX96150.1 - 1.6 8.7 10.0 1.7 8.6 0.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Beta_helix PF13229.1 KFX96153.1 - 1.2e-11 44.6 16.9 5.1e-07 29.5 4.9 2.9 2 1 0 2 2 2 2 Right handed beta helix region Sulfatase PF00884.18 KFX96154.1 - 3.9e-44 151.0 0.2 1.4e-41 142.7 0.0 2.7 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 KFX96154.1 - 9.5e-07 28.4 0.0 1.5e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 KFX96154.1 - 0.012 15.9 0.1 0.022 15.0 0.1 1.4 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Sugar_tr PF00083.19 KFX96155.1 - 1.9e-96 323.3 30.0 2.4e-96 323.0 20.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX96155.1 - 6.9e-25 87.4 21.1 6.9e-25 87.4 14.6 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.8 KFX96155.1 - 0.023 12.8 11.1 0.027 12.5 3.6 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Fungal_trans PF04082.13 KFX96156.1 - 4.9e-16 58.3 0.1 7.5e-16 57.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX96156.1 - 0.023 14.6 3.8 0.051 13.4 2.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_C PF05199.8 KFX96157.1 - 8.2e-30 103.9 0.1 1.6e-29 103.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Glyco_hydro_43 PF04616.9 KFX96157.1 - 2.7e-29 102.1 0.4 4.6e-29 101.3 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Beta_helix PF13229.1 KFX96158.1 - 1.4e-08 34.6 14.6 6.4e-05 22.7 4.2 2.7 1 1 1 2 2 2 2 Right handed beta helix region Chondroitinas_B PF14592.1 KFX96158.1 - 2e-06 26.8 0.0 3.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Chondroitinase B Sugar_tr PF00083.19 KFX96159.1 - 9.1e-74 248.6 21.7 1.1e-73 248.3 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX96159.1 - 1e-21 77.0 23.3 1e-21 77.0 16.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 KFX96160.1 - 3.2e-48 164.2 1.6 1.6e-29 102.7 0.3 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX96160.1 - 5.2e-08 32.6 5.1 5.2e-08 32.6 3.5 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.8 KFX96161.1 - 1.8e-06 27.3 0.3 3.4e-06 26.4 0.2 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX96161.1 - 5.5e-06 26.4 0.2 1.4e-05 25.1 0.1 1.8 2 0 0 2 2 2 1 NADH(P)-binding DapB_N PF01113.15 KFX96161.1 - 0.03 14.2 0.1 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 KFX96161.1 - 0.031 14.2 0.4 0.19 11.7 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain Epimerase PF01370.16 KFX96161.1 - 0.034 13.5 0.2 0.087 12.2 0.1 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Antig_Caf1 PF09255.5 KFX96161.1 - 0.053 13.4 0.0 0.14 12.0 0.0 1.6 2 0 0 2 2 2 0 Caf1 Capsule antigen Semialdhyde_dh PF01118.19 KFX96161.1 - 0.053 13.8 1.0 0.2 11.9 0.2 2.2 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain COX8 PF02285.10 KFX96161.1 - 0.13 11.7 0.0 0.35 10.4 0.0 1.7 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIII PAN_4 PF14295.1 KFX96162.1 - 0.0018 17.9 23.4 0.0068 16.0 1.3 3.5 2 1 1 3 3 3 2 PAN domain MANEC PF07502.9 KFX96162.1 - 0.0049 16.8 7.6 0.43 10.6 1.3 2.5 2 0 0 2 2 2 2 MANEC domain NmrA PF05368.8 KFX96163.1 - 9.6e-30 103.5 0.3 1.1e-29 103.3 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX96163.1 - 7.5e-16 58.6 0.2 2e-14 54.0 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KFX96163.1 - 0.00026 20.4 0.1 0.015 14.7 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KFX96163.1 - 0.0072 16.6 0.6 0.017 15.4 0.1 1.9 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KFX96163.1 - 0.013 15.3 3.0 0.09 12.6 0.2 2.6 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 KFX96163.1 - 0.074 11.9 0.3 0.37 9.6 0.1 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.13 KFX96164.1 - 1.3e-17 63.5 0.3 3.7e-17 62.0 0.0 1.9 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX96164.1 - 4.8e-09 35.9 8.6 4.8e-09 35.9 6.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VWA_2 PF13519.1 KFX96165.1 - 0.00011 22.3 0.0 0.00023 21.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KFX96165.1 - 0.00039 20.2 0.0 0.0012 18.6 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain adh_short PF00106.20 KFX96166.1 - 2e-07 31.0 0.1 6.5e-07 29.4 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX96166.1 - 4.4e-05 23.2 0.0 0.00075 19.2 0.0 2.2 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KFX96166.1 - 0.0021 17.8 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Fungal_trans_2 PF11951.3 KFX96167.1 - 1.3e-63 214.9 0.7 1.5e-63 214.6 0.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX96168.1 - 0.31 10.9 11.3 4.3 7.3 7.9 2.2 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CFIA_Pcf11 PF11526.3 KFX96169.1 - 0.14 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 GST_N_3 PF13417.1 KFX96170.1 - 5e-14 52.2 0.0 8.8e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KFX96170.1 - 4.6e-11 42.7 0.0 8.8e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFX96170.1 - 2.6e-10 40.1 0.0 6.9e-10 38.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFX96170.1 - 1.5e-09 37.7 0.0 2.4e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFX96170.1 - 5.2e-06 26.2 0.0 9.3e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFX96170.1 - 6.3e-06 26.5 0.0 1.1e-05 25.8 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Zn_clus PF00172.13 KFX96171.1 - 8.7e-07 28.7 11.6 3e-06 27.0 8.0 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_18 PF12847.2 KFX96172.1 - 1.1e-10 42.1 0.0 2.6e-10 40.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX96172.1 - 4e-07 29.8 0.0 7.5e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX96172.1 - 8.6e-05 22.1 0.1 0.00092 18.8 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX96172.1 - 0.00027 21.2 0.0 0.00071 19.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KFX96172.1 - 0.00047 19.7 0.0 0.00079 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 KFX96172.1 - 0.00049 20.5 0.0 0.005 17.2 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 KFX96172.1 - 0.0035 16.7 0.0 0.01 15.2 0.0 1.7 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW GCD14 PF08704.5 KFX96172.1 - 0.0045 16.5 0.0 0.0077 15.7 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.13 KFX96172.1 - 0.0064 15.6 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Fibrillarin PF01269.12 KFX96172.1 - 0.024 13.5 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin FtsJ PF01728.14 KFX96172.1 - 0.03 14.3 0.0 0.057 13.4 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_11 PF08241.7 KFX96172.1 - 0.032 14.7 0.0 0.098 13.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 KFX96172.1 - 0.11 11.9 0.0 2.1 7.7 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase TehB PF03848.9 KFX96172.1 - 0.16 11.1 0.0 5 6.2 0.0 2.1 2 0 0 2 2 2 0 Tellurite resistance protein TehB NAD_binding_1 PF00175.16 KFX96174.1 - 1.2e-14 54.7 0.0 1.7e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KFX96174.1 - 9.4e-06 25.6 0.0 1.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 KFX96174.1 - 0.00047 20.2 0.0 0.0009 19.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain PEMT PF04191.8 KFX96175.1 - 1.2e-57 192.4 11.8 4.6e-36 123.1 1.6 3.2 3 0 0 3 3 3 2 Phospholipid methyltransferase ParA PF10609.4 KFX96176.1 - 4.1e-35 119.4 0.1 1e-34 118.2 0.0 1.6 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 KFX96176.1 - 2.7e-16 59.5 0.0 4.1e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KFX96176.1 - 2.5e-05 24.2 0.0 6.8e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 KFX96176.1 - 0.00025 20.2 0.0 0.0028 16.7 0.1 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 KFX96176.1 - 0.00082 18.5 0.0 0.0016 17.5 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 KFX96176.1 - 0.0086 15.6 0.0 2.6 7.6 0.0 2.2 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KFX96176.1 - 0.01 15.0 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFX96176.1 - 0.016 14.6 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KFX96176.1 - 0.017 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KFX96176.1 - 0.024 14.3 1.1 0.5 10.1 0.1 2.5 2 1 0 2 2 2 0 Part of AAA domain AAA_22 PF13401.1 KFX96176.1 - 0.064 13.4 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 KFX96176.1 - 0.067 12.6 0.0 0.14 11.5 0.0 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Fer4_NifH PF00142.13 KFX96176.1 - 0.081 12.0 0.0 0.7 9.0 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family RNA_helicase PF00910.17 KFX96176.1 - 0.09 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 KFX96176.1 - 0.092 12.7 0.0 0.22 11.4 0.1 1.5 2 0 0 2 2 1 0 AAA ATPase domain Zn_Tnp_IS1595 PF12760.2 KFX96176.1 - 0.11 12.3 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 Transposase zinc-ribbon domain AAA_5 PF07728.9 KFX96176.1 - 0.13 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zn_clus PF00172.13 KFX96177.1 - 0.00016 21.5 89.3 0.00025 20.9 6.5 9.8 6 3 2 8 8 8 6 Fungal Zn(2)-Cys(6) binuclear cluster domain Ras PF00071.17 KFX96178.1 - 7.4e-58 194.5 0.2 1.1e-57 194.0 0.2 1.2 1 0 0 1 1 1 1 Ras family MoCF_biosynth PF00994.19 KFX96178.1 - 2e-26 92.0 0.0 1e-25 89.7 0.0 2.1 2 0 0 2 2 2 1 Probable molybdopterin binding domain Miro PF08477.8 KFX96178.1 - 3.4e-17 63.0 0.0 5.9e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFX96178.1 - 1.1e-06 28.0 0.0 1.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFX96178.1 - 1.5e-05 24.4 0.1 4.8e-05 22.8 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_25 PF13481.1 KFX96178.1 - 0.019 14.3 0.0 0.5 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KFX96178.1 - 0.019 14.8 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF605 PF04652.11 KFX96178.1 - 0.23 10.8 2.0 0.32 10.3 1.4 1.1 1 0 0 1 1 1 0 Vta1 like NAD_binding_5 PF07994.7 KFX96187.1 - 4e-112 374.5 0.3 5e-112 374.1 0.2 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 KFX96187.1 - 2.5e-46 156.0 0.3 5.6e-46 154.9 0.2 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Cupin_2 PF07883.6 KFX96188.1 - 5.2e-08 32.2 0.2 6.5e-08 31.9 0.1 1.1 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KFX96188.1 - 0.0092 15.6 0.0 0.0099 15.5 0.0 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain Cwf_Cwc_15 PF04889.7 KFX96189.1 - 1.9e-84 283.1 12.5 2.2e-84 283.0 8.7 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.4 KFX96189.1 - 3.5e-05 23.3 5.6 4.5e-05 23.0 3.9 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein GEMIN8 PF15348.1 KFX96189.1 - 0.23 11.4 7.9 0.3 11.1 5.5 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Upf2 PF04050.9 KFX96189.1 - 1.2 8.9 18.5 2 8.1 12.8 1.4 1 0 0 1 1 1 0 Up-frameshift suppressor 2 Spore_coat_CotO PF14153.1 KFX96189.1 - 1.6 8.1 11.2 2.2 7.6 7.7 1.2 1 0 0 1 1 1 0 Spore coat protein CotO SAPS PF04499.10 KFX96189.1 - 2.7 6.5 6.8 3.1 6.3 4.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 KFX96189.1 - 4.2 5.2 14.9 5.1 5.0 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 KFX96189.1 - 8.2 6.2 13.0 10 5.9 9.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Arginosuc_synth PF00764.14 KFX96195.1 - 4e-82 276.3 0.0 4.9e-82 276.0 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Arginosuc_synth PF00764.14 KFX96196.1 - 5.5e-59 200.1 0.0 6.5e-59 199.9 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 KFX96196.1 - 0.00061 19.3 0.0 0.00063 19.3 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 KFX96196.1 - 0.0023 17.2 0.0 0.0028 16.9 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 KFX96196.1 - 0.12 10.8 0.0 0.15 10.5 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase Allantoicase PF03561.10 KFX96197.1 - 1.2e-98 326.7 0.0 1.9e-52 176.7 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat Abhydrolase_6 PF12697.2 KFX96198.1 - 5.7e-29 101.6 0.1 7.6e-29 101.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX96198.1 - 8.2e-12 45.0 0.0 1.8e-11 43.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX96198.1 - 4.5e-07 29.6 0.0 4.2e-06 26.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KFX96198.1 - 0.0002 21.1 0.0 0.00049 19.8 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Tup_N PF08581.5 KFX96199.1 - 0.25 11.5 23.5 1 9.5 0.1 6.9 5 1 1 6 6 6 0 Tup N-terminal Ribosomal_L27e PF01777.13 KFX96200.1 - 1.4e-37 127.6 3.0 1.8e-37 127.3 2.1 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 KFX96200.1 - 0.0014 18.2 1.5 0.0021 17.6 0.1 2.0 2 0 0 2 2 2 1 KOW motif ECM11 PF15463.1 KFX96200.1 - 0.18 12.1 1.7 0.2 11.9 0.1 1.7 2 0 0 2 2 2 0 Extracellular mutant protein 11 GAF PF01590.21 KFX96201.1 - 4.1e-05 23.7 0.0 0.00012 22.1 0.0 1.8 1 0 0 1 1 1 1 GAF domain ATP-synt_ab PF00006.20 KFX96202.1 - 9.2e-71 237.7 0.0 1.5e-70 237.0 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFX96202.1 - 3.2e-27 95.2 0.6 8e-27 93.9 0.1 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KFX96202.1 - 1.1e-15 57.5 2.7 2.7e-15 56.3 1.9 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KFX96202.1 - 0.011 15.6 1.1 0.028 14.3 0.6 1.9 2 0 0 2 2 2 0 HAS barrel domain Arch_ATPase PF01637.13 KFX96202.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 KFX96202.1 - 0.031 13.6 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Btz PF09405.5 KFX96218.1 - 1.9e-11 44.1 0.7 4.7e-11 42.8 0.0 1.9 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding ZZ PF00569.12 KFX96219.1 - 7.6e-20 70.1 54.4 5.7e-07 28.9 5.0 4.6 4 0 0 4 4 4 4 Zinc finger, ZZ type GNVR PF13807.1 KFX96219.1 - 0.14 11.8 0.5 0.42 10.4 0.3 1.8 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase MBF1 PF08523.5 KFX96220.1 - 4.6e-26 90.6 1.4 8.1e-26 89.8 1.0 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 KFX96220.1 - 2.1e-09 37.0 0.0 3.2e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 KFX96220.1 - 0.00093 19.2 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 KFX96220.1 - 0.0043 17.2 0.0 0.0082 16.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MRP-L27 PF09809.4 KFX96220.1 - 0.047 13.3 0.1 0.05 13.2 0.1 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L27 RF-1 PF00472.15 KFX96222.1 - 3.1e-12 46.3 0.9 6.6e-12 45.2 0.6 1.5 1 0 0 1 1 1 1 RF-1 domain RRM_1 PF00076.17 KFX96223.1 - 1.7e-10 40.3 0.0 3e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX96223.1 - 3.9e-07 29.9 0.0 7.5e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX96223.1 - 0.097 12.5 0.2 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LETM1 PF07766.8 KFX96224.1 - 6.7e-12 45.0 3.0 1.8e-10 40.3 0.2 2.2 1 1 1 2 2 2 2 LETM1-like protein Amidohydro_4 PF13147.1 KFX96225.1 - 1e-07 32.2 1.8 1.7e-07 31.6 1.2 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 KFX96225.1 - 9.3e-07 28.6 0.2 1.7e-06 27.8 0.1 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 KFX96225.1 - 0.0014 18.4 1.0 0.0082 15.8 0.7 2.0 1 1 0 1 1 1 1 Amidohydrolase family CoA_binding_2 PF13380.1 KFX96225.1 - 0.05 13.7 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 CoA binding domain Pkinase PF00069.20 KFX96227.1 - 1.5e-58 197.9 0.0 2.1e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX96227.1 - 2e-27 95.9 0.0 2.5e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX96227.1 - 1.9e-07 30.3 0.0 2.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFX96227.1 - 0.00087 19.0 0.0 0.00087 19.0 0.0 2.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 KFX96227.1 - 0.0048 15.9 0.0 0.0083 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Podoplanin PF05808.6 KFX96229.1 - 0.013 15.1 0.5 0.025 14.1 0.3 1.5 1 0 0 1 1 1 0 Podoplanin MtrF PF09472.5 KFX96229.1 - 1.3 8.3 3.9 14 4.9 0.0 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) ATG27 PF09451.5 KFX96230.1 - 1.8e-67 227.4 0.0 2.4e-67 226.9 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 KFX96230.1 - 7.2e-06 25.8 0.0 0.0012 18.6 0.0 2.8 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat Glutaredoxin PF00462.19 KFX96231.1 - 1.7e-12 47.1 0.0 5.4e-12 45.5 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin Mito_carr PF00153.22 KFX96266.1 - 2.1e-38 129.9 2.2 3.4e-13 49.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ank_2 PF12796.2 KFX96267.1 - 2.7e-66 219.9 11.0 9.6e-24 83.5 0.5 3.7 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFX96267.1 - 2.5e-48 159.5 22.8 5.2e-07 29.1 0.1 8.0 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 KFX96267.1 - 2.7e-42 142.3 11.9 3.4e-10 40.1 0.0 5.4 2 2 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX96267.1 - 3.5e-40 131.9 7.2 0.00012 21.9 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 KFX96267.1 - 4.8e-32 109.2 18.4 0.0001 22.3 0.1 7.9 1 1 7 8 8 8 7 Ankyrin repeats (many copies) DUF2384 PF09722.5 KFX96267.1 - 0.0047 16.7 0.1 2.6 7.9 0.0 4.0 4 0 0 4 4 4 1 Protein of unknown function (DUF2384) FA PF08736.6 KFX96267.1 - 0.0068 16.1 0.1 0.61 9.9 0.0 2.8 3 0 0 3 3 3 1 FERM adjacent (FA) Shigella_OspC PF06128.6 KFX96267.1 - 0.074 12.5 0.0 20 4.5 0.0 2.8 1 1 1 3 3 3 0 Shigella flexneri OspC protein polyprenyl_synt PF00348.12 KFX96268.1 - 6.3e-38 130.1 0.0 2.1e-18 66.0 0.0 2.3 1 1 1 2 2 2 2 Polyprenyl synthetase Terpene_synth_C PF03936.11 KFX96268.1 - 8.4e-05 21.9 0.2 0.013 14.7 0.0 3.2 2 1 1 3 3 3 1 Terpene synthase family, metal binding domain Glyco_transf_28 PF03033.15 KFX96283.1 - 7.4e-20 71.1 0.0 1.6e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KFX96283.1 - 2.4e-06 26.4 0.0 3.6e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 KFX96283.1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain MARVEL PF01284.18 KFX96285.1 - 0.00039 20.2 18.9 0.0031 17.3 13.0 2.0 1 1 1 2 2 2 2 Membrane-associating domain NUDE_C PF04880.8 KFX96287.1 - 3.1e-20 73.1 0.9 3.1e-20 73.1 0.6 4.1 2 1 2 4 4 1 1 NUDE protein, C-terminal conserved region WEMBL PF05701.6 KFX96287.1 - 0.0037 15.7 22.3 0.0058 15.1 15.4 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Tropomyosin_1 PF12718.2 KFX96287.1 - 0.059 13.2 30.2 1.3 8.9 13.4 4.2 2 1 1 3 3 3 0 Tropomyosin like IncA PF04156.9 KFX96287.1 - 0.28 10.7 30.6 0.038 13.5 7.6 2.9 2 1 1 3 3 3 0 IncA protein ATG16 PF08614.6 KFX96287.1 - 0.34 10.6 23.4 0.69 9.7 8.9 3.2 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DDE_Tnp_IS66 PF03050.9 KFX96287.1 - 1.4 8.1 6.0 3.1 6.9 4.2 1.5 1 0 0 1 1 1 0 Transposase IS66 family AAA_13 PF13166.1 KFX96287.1 - 1.6 7.0 16.0 2.8 6.2 11.1 1.3 1 0 0 1 1 1 0 AAA domain Cep57_MT_bd PF06657.8 KFX96287.1 - 2.3 8.1 9.9 9.6 6.2 0.2 3.2 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 WXG100 PF06013.7 KFX96287.1 - 4.8 7.2 12.0 43 4.1 3.6 4.1 3 1 1 4 4 4 0 Proteins of 100 residues with WXG DUF904 PF06005.7 KFX96287.1 - 5.6 7.3 27.0 0.15 12.3 2.6 4.0 2 1 3 5 5 5 0 Protein of unknown function (DUF904) DUF3584 PF12128.3 KFX96287.1 - 7.9 3.6 21.4 12 3.0 14.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Filament PF00038.16 KFX96287.1 - 8.1 5.8 27.2 8.8 5.6 17.2 2.1 2 1 0 2 2 2 0 Intermediate filament protein FlxA PF14282.1 KFX96287.1 - 8.4 6.3 15.5 0.89 9.5 3.4 3.1 3 1 0 3 3 3 0 FlxA-like protein CENP-F_leu_zip PF10473.4 KFX96287.1 - 9.9 6.0 31.9 0.43 10.4 4.7 3.4 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ACC_central PF08326.7 KFX96288.1 - 3.7e-267 888.1 0.0 4.6e-267 887.8 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 KFX96288.1 - 7.4e-180 598.5 0.0 9.6e-180 598.1 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KFX96288.1 - 6.7e-52 175.8 0.0 1.3e-51 174.9 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KFX96288.1 - 4.6e-24 84.6 0.1 9e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KFX96288.1 - 3.4e-21 75.2 0.0 8.1e-19 67.5 0.0 3.8 4 0 0 4 4 4 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 KFX96288.1 - 5.5e-17 61.1 0.1 1.7e-16 59.6 0.1 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KFX96288.1 - 1.8e-10 40.8 0.0 5.5e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KFX96288.1 - 9.8e-08 31.0 0.0 0.0013 17.5 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KFX96288.1 - 0.0012 18.3 0.0 0.0024 17.2 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KFX96288.1 - 0.021 14.6 0.0 0.068 13.0 0.0 1.9 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp PF02222.17 KFX96288.1 - 0.023 14.0 0.0 0.057 12.7 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KFX96288.1 - 0.06 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like DUF3492 PF11997.3 KFX96289.1 - 0.025 14.1 0.3 0.033 13.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) DivIC PF04977.10 KFX96289.1 - 0.23 10.9 4.1 0.45 10.0 2.9 1.5 1 0 0 1 1 1 0 Septum formation initiator HABP4_PAI-RBP1 PF04774.10 KFX96289.1 - 0.87 10.1 4.6 2.9 8.4 3.3 1.6 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family CCDC92 PF14916.1 KFX96290.1 - 0.011 15.3 0.9 0.011 15.3 0.6 1.8 2 0 0 2 2 2 0 Coiled-coil domain of unknown function RPOL_N PF14700.1 KFX96290.1 - 0.017 14.3 0.3 0.028 13.6 0.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal Vps39_2 PF10367.4 KFX96290.1 - 0.031 14.4 1.2 0.035 14.2 0.2 1.5 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 DHDPS PF00701.17 KFX96290.1 - 0.1 11.2 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family AnfG_VnfG PF03139.10 KFX96290.1 - 0.1 12.4 1.1 0.22 11.3 0.1 1.9 2 0 0 2 2 2 0 Vanadium/alternative nitrogenase delta subunit Cep57_CLD_2 PF14197.1 KFX96290.1 - 0.15 12.0 5.8 1.1 9.2 0.3 2.6 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 DivIC PF04977.10 KFX96290.1 - 0.22 11.0 1.7 2.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Septum formation initiator F-box-like PF12937.2 KFX96292.1 - 4e-06 26.4 0.9 1.2e-05 24.8 0.6 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KFX96292.1 - 1.4 8.7 4.6 4.6 7.0 2.4 2.4 2 1 0 2 2 2 0 F-box domain Methyltransf_23 PF13489.1 KFX96293.1 - 3.8e-19 68.9 0.0 6.3e-19 68.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX96293.1 - 2.8e-14 52.9 0.1 8e-13 48.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX96293.1 - 1.3e-12 48.0 0.0 2.5e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX96293.1 - 1.1e-11 45.2 0.1 1.6e-10 41.5 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX96293.1 - 5.1e-11 42.9 0.0 6e-10 39.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX96293.1 - 6.3e-07 29.6 0.0 1.6e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KFX96293.1 - 0.00011 21.2 0.0 0.00027 20.0 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 KFX96293.1 - 0.00017 21.5 0.0 0.00071 19.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX96293.1 - 0.00081 18.8 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 KFX96293.1 - 0.0012 18.8 0.0 0.0019 18.2 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 KFX96293.1 - 0.0019 17.3 0.0 0.0035 16.5 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KFX96293.1 - 0.0028 16.8 0.0 0.069 12.2 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 KFX96293.1 - 0.0034 16.8 0.0 0.0088 15.5 0.0 1.8 2 1 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 KFX96293.1 - 0.0054 15.8 0.0 0.029 13.4 0.0 2.2 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase TehB PF03848.9 KFX96293.1 - 0.035 13.2 0.0 8 5.5 0.0 2.1 2 0 0 2 2 2 0 Tellurite resistance protein TehB DUF3489 PF11994.3 KFX96293.1 - 0.038 13.9 0.1 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) Methyltransf_2 PF00891.13 KFX96294.1 - 5.6e-22 78.1 0.0 8.9e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KFX96294.1 - 0.0023 17.6 0.0 0.0047 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Asp PF00026.18 KFX96295.1 - 2.8e-64 217.3 4.1 3.6e-64 216.9 2.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFX96295.1 - 1.1e-06 28.7 0.0 3.7e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KFX96295.1 - 1.2e-05 25.7 0.8 0.017 15.5 0.1 3.0 2 1 0 2 2 2 2 Aspartyl protease Glyoxalase_2 PF12681.2 KFX96296.1 - 2.4e-12 47.4 0.1 3.3e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KFX96296.1 - 5.1e-06 26.4 0.0 7.7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TSC22 PF01166.13 KFX96296.1 - 0.091 12.7 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 TSC-22/dip/bun family SH3_2 PF07653.12 KFX96297.1 - 4.2e-07 29.3 0.0 6.2e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KFX96297.1 - 6.3e-07 28.6 0.0 1.6e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 SH3 domain Peroxin-13_N PF04088.8 KFX96297.1 - 2.2e-06 27.6 0.1 3.1e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_9 PF14604.1 KFX96297.1 - 4.2e-06 26.2 0.1 7.4e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 KFX96297.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain Ferric_reduct PF01794.14 KFX96299.1 - 2.6e-10 40.4 5.0 2.6e-10 40.4 3.5 2.2 1 1 1 2 2 2 1 Ferric reductase like transmembrane component YTH PF04146.10 KFX96302.1 - 1.8e-52 176.6 0.0 2.3e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 YT521-B-like domain Med3 PF11593.3 KFX96302.1 - 5.8 6.0 7.0 7.3 5.7 4.9 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Drf_GBD PF06371.8 KFX96307.1 - 1.2e-67 226.9 0.9 3e-67 225.6 0.0 2.0 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 KFX96307.1 - 9.4e-54 181.8 2.1 1.6e-52 177.8 1.4 2.4 1 1 0 1 1 1 1 Diaphanous FH3 Domain DEAD PF00270.24 KFX96333.1 - 7.4e-32 110.1 0.0 1.3e-30 106.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KFX96333.1 - 2.7e-09 37.1 0.1 7.8e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KFX96333.1 - 2e-06 27.5 0.0 6.6e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KFX96333.1 - 0.00035 20.7 0.4 0.002 18.2 0.3 2.3 1 1 0 1 1 1 1 AAA domain FliS PF02561.9 KFX96333.1 - 0.07 12.9 0.3 0.22 11.3 0.2 1.8 2 0 0 2 2 2 0 Flagellar protein FliS DUF4315 PF14193.1 KFX96334.1 - 0.038 13.9 0.2 0.038 13.9 0.2 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4315) Dict-STAT-coil PF09267.5 KFX96334.1 - 0.16 12.1 6.3 1.3 9.2 0.5 3.1 3 0 0 3 3 3 0 Dictyostelium STAT, coiled coil CPSase_L_D2 PF02786.12 KFX96335.1 - 8.4e-110 365.0 0.2 1.6e-83 279.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 KFX96335.1 - 6.4e-42 142.2 0.0 1.6e-41 140.9 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 KFX96335.1 - 8.3e-38 129.9 0.2 6.1e-21 74.9 0.1 2.5 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 KFX96335.1 - 1.3e-34 118.6 0.0 7.6e-17 61.4 0.0 2.8 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 KFX96335.1 - 1e-23 83.6 0.0 4.2e-10 38.8 0.0 3.5 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KFX96335.1 - 2.8e-19 69.1 0.1 1.3e-08 34.3 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KFX96335.1 - 5.3e-17 61.8 0.8 1.6e-08 34.1 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 KFX96335.1 - 8.5e-11 41.6 0.1 1.1e-07 31.5 0.0 2.7 3 0 0 3 3 3 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KFX96335.1 - 1.8e-05 24.6 0.2 0.15 11.8 0.0 2.7 3 0 0 3 3 2 2 ATP-grasp domain GARS_A PF01071.14 KFX96335.1 - 3.6e-05 23.4 0.4 0.025 14.1 0.1 2.6 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 KFX96335.1 - 0.0014 17.8 0.1 0.14 11.3 0.0 2.8 2 0 0 2 2 2 1 ATP-grasp domain MGS PF02142.17 KFX96335.1 - 0.018 14.9 0.0 0.082 12.8 0.0 2.2 2 0 0 2 2 2 0 MGS-like domain Epimerase PF01370.16 KFX96335.1 - 0.039 13.3 0.0 0.54 9.6 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family EAP30 PF04157.11 KFX96335.1 - 0.16 11.0 0.0 0.61 9.1 0.0 1.9 2 0 0 2 2 2 0 EAP30/Vps36 family tRNA-synt_2d PF01409.15 KFX96336.1 - 5.3e-80 268.1 0.0 7.7e-80 267.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 KFX96336.1 - 2.5e-05 23.2 0.3 0.00024 19.9 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 KFX96336.1 - 2.5e-05 23.9 0.0 0.00015 21.4 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Tox-REase-5 PF15648.1 KFX96337.1 - 0.0051 17.0 0.1 0.0062 16.8 0.1 1.2 1 0 0 1 1 1 1 Restriction endonuclease fold toxin 5 Sec66 PF09802.4 KFX96338.1 - 1.9e-79 265.4 0.0 2.3e-79 265.2 0.0 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 NPL4 PF05021.10 KFX96339.1 - 9e-127 422.4 0.0 1.1e-126 422.1 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 KFX96339.1 - 2.8e-70 234.6 0.0 4.3e-70 234.0 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 KFX96339.1 - 0.00018 21.7 0.0 0.00053 20.2 0.0 1.8 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 SLAC1 PF03595.12 KFX96340.1 - 5e-59 199.6 41.4 5.6e-59 199.4 28.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel ORC3_N PF07034.6 KFX96341.1 - 6.6e-45 153.4 2.5 1.9e-44 152.0 1.7 1.7 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Propep_M14 PF02244.11 KFX96341.1 - 0.026 14.1 0.7 7 6.4 0.1 2.5 2 0 0 2 2 2 0 Carboxypeptidase activation peptide PPR_3 PF13812.1 KFX96342.1 - 1.8e-05 24.6 0.5 0.14 12.5 0.0 5.3 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 KFX96342.1 - 0.007 16.3 0.0 6.5 6.8 0.0 4.4 4 0 0 4 4 4 1 PPR repeat family DUF4187 PF13821.1 KFX96343.1 - 6.1e-20 70.5 2.7 2.2e-19 68.7 1.9 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 KFX96343.1 - 1.7e-10 40.4 1.4 3.5e-10 39.4 1.0 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KFX96343.1 - 0.00087 19.0 1.4 0.00087 19.0 1.0 2.6 2 0 0 2 2 2 1 DExH-box splicing factor binding site Nop14 PF04147.7 KFX96344.1 - 2.4e-261 869.4 16.7 3e-261 869.0 11.6 1.1 1 0 0 1 1 1 1 Nop14-like family DUF3628 PF12300.3 KFX96345.1 - 0.017 15.1 1.1 0.54 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3628) BTB PF00651.26 KFX96345.1 - 0.082 12.8 0.0 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 BTB/POZ domain Pkinase PF00069.20 KFX96346.1 - 4.9e-67 225.7 0.0 6.5e-67 225.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX96346.1 - 7.2e-34 117.0 0.0 1.2e-33 116.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX96346.1 - 8.1e-05 21.7 0.0 0.00047 19.2 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 KFX96346.1 - 0.00052 19.1 0.0 0.00086 18.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFX96346.1 - 0.004 16.9 0.1 0.01 15.6 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFX96346.1 - 0.13 11.0 0.5 4 6.1 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Mo25 PF08569.6 KFX96349.1 - 2.4e-123 411.4 0.0 4.5e-123 410.5 0.0 1.5 1 0 0 1 1 1 1 Mo25-like SWIB PF02201.13 KFX96349.1 - 8.6e-12 44.5 0.0 1.7e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain Nucleoplasmin PF03066.10 KFX96349.1 - 0.00055 19.4 1.5 0.0011 18.5 1.0 1.5 1 0 0 1 1 1 1 Nucleoplasmin CENP-B_dimeris PF09026.5 KFX96349.1 - 0.11 12.7 6.0 0.26 11.5 4.1 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 KFX96349.1 - 0.33 10.1 4.5 0.5 9.5 3.1 1.2 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.1 KFX96349.1 - 1.4 9.2 10.1 0.096 12.9 3.2 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Methyltransf_31 PF13847.1 KFX96350.1 - 1.8e-12 47.0 0.0 3.6e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFX96350.1 - 7.7e-12 44.9 0.0 1.5e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KFX96350.1 - 3.4e-11 43.7 0.1 1.1e-10 42.0 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX96350.1 - 3.7e-10 40.1 0.0 1.2e-09 38.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX96350.1 - 1.9e-09 37.5 0.0 3.9e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX96350.1 - 4.5e-07 29.4 0.1 7.9e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KFX96350.1 - 6.6e-07 29.1 0.0 1.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX96350.1 - 6.4e-06 26.4 0.0 1.6e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KFX96350.1 - 3.4e-05 23.0 0.1 0.00037 19.6 0.0 2.2 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Met_10 PF02475.11 KFX96350.1 - 0.00026 20.6 0.0 0.0005 19.7 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.4 KFX96350.1 - 0.00034 20.1 0.0 0.00057 19.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.6 KFX96350.1 - 0.00069 18.4 0.0 0.001 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 KFX96350.1 - 0.0013 19.1 0.0 0.0033 17.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 KFX96350.1 - 0.0013 17.7 0.0 0.0027 16.6 0.0 1.5 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase FtsJ PF01728.14 KFX96350.1 - 0.0018 18.2 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 KFX96350.1 - 0.0022 17.5 0.0 0.0037 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 KFX96350.1 - 0.004 16.2 0.0 0.0069 15.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family UPF0020 PF01170.13 KFX96350.1 - 0.0057 16.2 0.1 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 WD40_alt PF14077.1 KFX96350.1 - 0.021 14.4 0.4 0.042 13.4 0.3 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif TehB PF03848.9 KFX96350.1 - 0.025 13.7 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_24 PF13578.1 KFX96350.1 - 0.043 14.6 0.0 0.31 11.8 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.10 KFX96350.1 - 0.072 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Packaging_FI PF14000.1 KFX96350.1 - 0.12 12.5 0.1 0.12 12.5 0.1 1.7 2 0 0 2 2 1 0 DNA packaging protein FI OPT PF03169.10 KFX96351.1 - 1.8e-154 515.5 26.9 2.1e-154 515.3 18.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Gly-zipper_Omp PF13488.1 KFX96351.1 - 0.11 12.1 5.5 0.34 10.5 0.1 3.4 3 0 0 3 3 3 0 Glycine zipper Rav1p_C PF12234.3 KFX96352.1 - 3.4e-265 881.1 0.1 4.6e-265 880.7 0.1 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal Sfi1 PF08457.5 KFX96352.1 - 1.8e-112 376.6 67.9 1.8e-112 376.6 47.0 2.0 1 1 0 2 2 2 1 Sfi1 spindle body protein WD40 PF00400.27 KFX96352.1 - 1.1e-05 25.0 0.1 0.032 14.1 0.0 4.2 3 0 0 3 3 3 2 WD domain, G-beta repeat tRNA-synt_1 PF00133.17 KFX96353.1 - 1e-219 730.5 0.0 1.4e-219 730.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KFX96353.1 - 3.3e-23 82.1 0.0 1.2e-22 80.2 0.0 2.0 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KFX96353.1 - 6.3e-19 67.8 0.2 5.8e-08 31.8 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 KFX96353.1 - 0.018 14.1 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Uso1_p115_head PF04869.9 KFX96354.1 - 8.8e-109 363.0 0.0 1.5e-108 362.3 0.0 1.4 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 KFX96354.1 - 1.3e-05 25.0 30.9 1.3e-05 25.0 21.4 3.3 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region XRN_N PF03159.13 KFX96355.1 - 1.7e-106 354.9 0.1 4.7e-106 353.4 0.0 1.9 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus RasGAP PF00616.14 KFX96355.1 - 6.1e-46 156.5 0.1 1.1e-45 155.6 0.1 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 KFX96355.1 - 1.5e-09 37.9 0.1 3.9e-09 36.5 0.1 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain zf-CCHC PF00098.18 KFX96355.1 - 0.31 11.0 2.8 0.72 9.9 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle FAD_binding_3 PF01494.14 KFX96356.1 - 9.6e-09 34.7 7.4 1.4e-06 27.6 1.6 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KFX96356.1 - 0.00055 19.9 1.4 0.0013 18.6 1.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KFX96356.1 - 0.0028 17.4 0.0 0.005 16.6 0.0 1.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.19 KFX96356.1 - 0.0041 16.0 4.3 0.018 13.9 1.2 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFX96356.1 - 0.051 13.4 0.7 0.13 12.1 0.5 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFX96356.1 - 0.092 11.8 0.5 0.15 11.1 0.4 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 KFX96356.1 - 0.14 10.9 1.2 0.58 8.9 0.6 1.9 2 0 0 2 2 2 0 FAD binding domain MFS_1 PF07690.11 KFX96357.1 - 5.1e-11 41.8 20.4 3.5e-09 35.8 13.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 KFX96357.1 - 0.071 13.0 2.0 0.22 11.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) SecD_SecF PF02355.11 KFX96357.1 - 0.1 11.7 4.3 3.5 6.7 0.1 2.8 3 0 0 3 3 3 0 Protein export membrane protein Acyl_transf_3 PF01757.17 KFX96357.1 - 0.24 10.2 17.2 0.03 13.1 6.7 2.2 2 1 0 2 2 2 0 Acyltransferase family DUF4131 PF13567.1 KFX96357.1 - 1.1 8.6 6.4 5.4 6.3 0.4 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) MerC PF03203.9 KFX96357.1 - 2.6 8.4 8.3 0.19 12.1 1.1 2.4 3 0 0 3 3 3 0 MerC mercury resistance protein DUF1772 PF08592.6 KFX96357.1 - 3.4 7.4 7.3 2.8 7.6 0.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) SPC12 PF06645.8 KFX96357.1 - 9.4 6.1 12.2 8.6 6.2 0.2 3.9 4 0 0 4 4 4 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Sec7 PF01369.15 KFX96359.1 - 6.5e-42 143.3 0.0 2.7e-41 141.3 0.0 2.0 2 0 0 2 2 2 1 Sec7 domain PH_9 PF15410.1 KFX96359.1 - 1.8e-20 73.2 0.0 3.7e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Pkinase PF00069.20 KFX96375.1 - 1.2e-11 44.2 0.0 5.1e-11 42.2 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain FAD_binding_8 PF08022.7 KFX96375.1 - 4e-10 39.5 0.2 8.5e-10 38.4 0.1 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KFX96375.1 - 2.1e-09 37.5 18.6 1.9e-08 34.4 6.6 2.6 2 0 0 2 2 2 2 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KFX96375.1 - 6.7e-07 29.3 0.0 1.9e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Pkinase_Tyr PF07714.12 KFX96375.1 - 8.8e-07 28.2 0.0 1.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2417 PF10329.4 KFX96375.1 - 1.2 8.4 5.7 6.4 6.1 0.3 2.2 1 1 1 2 2 2 0 Region of unknown function (DUF2417) Abi PF02517.11 KFX96379.1 - 2.7e-11 43.4 14.0 2.7e-11 43.4 9.7 2.7 2 1 0 2 2 2 1 CAAX protease self-immunity MBOAT PF03062.14 KFX96380.1 - 1.2e-42 146.2 5.8 1.2e-42 146.2 4.0 1.9 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Sec1 PF00995.18 KFX96381.1 - 1.2e-152 509.4 0.3 1.4e-152 509.2 0.2 1.0 1 0 0 1 1 1 1 Sec1 family Glyco_hydro_7 PF00840.15 KFX96390.1 - 2e-216 718.4 25.0 2.4e-216 718.1 17.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 KFX96390.1 - 1.5e-13 50.1 13.3 1.5e-13 50.1 9.2 4.6 5 0 0 5 5 5 1 Fungal cellulose binding domain BetaGal_dom4_5 PF13364.1 KFX96393.1 - 5.1e-19 68.5 0.1 8.2e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Glyco_hydro_31 PF01055.21 KFX96394.1 - 9.2e-170 565.2 0.2 1.2e-169 564.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KFX96394.1 - 1.9e-11 43.6 1.6 3.3e-10 39.6 0.5 2.8 2 0 0 2 2 2 1 Galactose mutarotase-like TIG PF01833.19 KFX96394.1 - 0.018 15.0 0.9 5.4 7.0 0.0 3.4 2 1 0 3 3 3 0 IPT/TIG domain BRCT PF00533.21 KFX96395.1 - 0.00032 20.7 0.0 0.0031 17.6 0.0 2.7 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Sugar_tr PF00083.19 KFX96399.1 - 1.9e-71 240.9 18.5 2.3e-70 237.4 12.8 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX96399.1 - 1.3e-16 60.3 26.8 4.5e-15 55.2 15.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Dioxygenase_C PF00775.16 KFX96400.1 - 9.4e-12 44.5 2.7 3e-11 42.9 1.8 1.9 1 1 0 1 1 1 1 Dioxygenase DUF4198 PF10670.4 KFX96400.1 - 0.029 14.3 0.1 0.35 10.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4198) Aldo_ket_red PF00248.16 KFX96401.1 - 2e-50 171.1 0.0 2.5e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Slx4 PF09494.5 KFX96402.1 - 6.3e-22 77.0 0.0 1.8e-21 75.6 0.0 1.8 2 0 0 2 2 2 1 Slx4 endonuclease Clathrin_H_link PF13838.1 KFX96402.1 - 0.066 13.1 0.9 0.69 9.8 0.3 2.4 2 0 0 2 2 2 0 Clathrin-H-link IER PF05760.7 KFX96403.1 - 2.6 7.8 7.9 3.4 7.5 5.4 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) Ribosomal_S21e PF01249.13 KFX96404.1 - 1.2e-36 124.4 0.1 1.4e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e ApbA_C PF08546.6 KFX96405.1 - 1.9e-24 86.0 0.0 3.6e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KFX96405.1 - 7e-24 83.9 0.1 1.3e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Zn_clus PF00172.13 KFX96405.1 - 0.0026 17.6 12.1 0.0042 16.9 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_A4 PF01828.12 KFX96406.1 - 5.4e-81 270.6 14.3 6.4e-81 270.3 9.9 1.1 1 0 0 1 1 1 1 Peptidase A4 family CHRD PF07452.7 KFX96406.1 - 1.1 9.8 4.4 10 6.7 2.6 2.6 1 1 1 2 2 2 0 CHRD domain Glyco_hydro_7 PF00840.15 KFX96407.1 - 1.8e-84 283.6 28.1 7.5e-28 97.0 5.6 5.0 1 1 3 4 4 4 4 Glycosyl hydrolase family 7 BNR PF02012.15 KFX96408.1 - 0.74 9.8 8.4 4.9 7.4 1.0 3.8 3 0 0 3 3 3 0 BNR/Asp-box repeat LIP PF03583.9 KFX96409.1 - 1.2e-65 221.6 1.0 1.6e-65 221.2 0.7 1.1 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_6 PF12697.2 KFX96409.1 - 1.5e-07 31.5 0.0 2.7e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFX96409.1 - 2e-06 27.1 0.2 0.00014 21.1 0.0 2.7 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFX96409.1 - 5.4e-06 26.2 0.2 1.6e-05 24.6 0.1 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFX96409.1 - 0.00029 20.3 0.0 0.00052 19.5 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.13 KFX96409.1 - 0.0028 16.9 0.0 0.0053 16.0 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family Cutinase PF01083.17 KFX96409.1 - 0.0052 16.5 0.2 0.013 15.2 0.0 1.7 2 0 0 2 2 2 1 Cutinase Abhydrolase_1 PF00561.15 KFX96409.1 - 0.05 13.1 0.0 0.11 12.0 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Amidase PF01425.16 KFX96410.1 - 1.6e-74 251.3 0.0 2.2e-74 250.9 0.0 1.2 1 0 0 1 1 1 1 Amidase p450 PF00067.17 KFX96411.1 - 1.6e-66 224.7 0.0 2.6e-66 224.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KFX96411.1 - 3.1e-39 134.7 23.6 3.1e-39 134.7 16.3 5.5 2 2 3 5 5 5 2 Major Facilitator Superfamily Transp_cyt_pur PF02133.10 KFX96411.1 - 4.3e-33 114.5 38.4 4.3e-33 114.5 26.6 2.6 2 0 0 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.13 KFX96411.1 - 1.2e-21 76.7 0.0 2.3e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX96411.1 - 1.9e-05 24.4 11.6 3.4e-05 23.6 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 KFX96412.1 - 1e-64 218.1 0.1 2.3e-64 216.9 0.0 1.6 2 0 0 2 2 2 1 Aldo/keto reductase family HET PF06985.6 KFX96412.1 - 7.8e-29 100.6 0.0 2.3e-28 99.0 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Clr2 PF10383.4 KFX96412.1 - 0.081 12.9 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 AHH PF14412.1 KFX96412.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Zip PF02535.17 KFX96416.1 - 8.8e-32 110.3 2.3 1e-31 110.1 1.6 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter E1_dh PF00676.15 KFX96417.1 - 8.3e-116 385.9 0.8 1e-115 385.6 0.5 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KFX96417.1 - 1.7e-05 23.8 0.0 3.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase WD40 PF00400.27 KFX96418.1 - 1.1e-53 177.3 18.1 2.3e-10 39.9 0.2 8.3 9 0 0 9 9 9 6 WD domain, G-beta repeat F-box-like PF12937.2 KFX96418.1 - 2.6e-11 43.0 0.3 5.2e-11 42.0 0.2 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 KFX96418.1 - 5.3e-09 34.7 8.7 0.007 14.5 0.5 4.6 1 1 4 5 5 5 4 Nucleoporin Nup120/160 F-box PF00646.28 KFX96418.1 - 9.8e-06 25.0 0.6 2.1e-05 24.0 0.4 1.6 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 KFX96418.1 - 0.00043 19.8 5.4 0.035 13.5 0.3 3.1 3 1 0 3 3 3 2 PQQ-like domain PQQ_3 PF13570.1 KFX96418.1 - 0.00072 19.7 0.3 6.4 7.2 0.0 5.3 5 1 0 5 5 5 1 PQQ-like domain Nucleoporin_N PF08801.6 KFX96418.1 - 0.0017 17.1 0.3 0.25 10.0 0.0 3.1 1 1 0 2 2 2 1 Nup133 N terminal like BBS2_Mid PF14783.1 KFX96418.1 - 0.022 14.5 0.2 2.8 7.7 0.0 3.5 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Methyltransf_23 PF13489.1 KFX96421.1 - 4.6e-19 68.6 0.0 8.5e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX96421.1 - 3.4e-07 29.9 0.0 2.4e-06 27.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX96421.1 - 3.6e-07 30.5 0.0 1.2e-06 28.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX96421.1 - 1.7e-06 28.5 0.0 9.8e-06 26.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX96421.1 - 2.1e-05 24.8 0.0 8.5e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX96421.1 - 0.0023 18.2 0.0 0.0059 16.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KFX96421.1 - 0.0047 16.9 0.0 0.043 13.7 0.0 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KFX96421.1 - 0.012 15.6 0.0 0.042 13.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KFX96421.1 - 0.028 13.5 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 KFX96421.1 - 0.031 13.3 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 KFX96421.1 - 0.036 13.4 0.0 0.09 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.13 KFX96422.1 - 1.6e-26 92.9 0.0 2.6e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KFX96422.1 - 6.3e-05 22.7 0.0 0.00014 21.5 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain MtrC PF04211.8 KFX96423.1 - 0.016 14.2 5.5 0.03 13.3 3.8 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit C adh_short PF00106.20 KFX96424.1 - 5.3e-14 52.4 0.2 1.7e-13 50.8 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KFX96424.1 - 0.0089 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KFX96424.1 - 0.0092 15.7 1.2 0.03 14.0 0.1 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.5 KFX96424.1 - 0.018 14.7 1.0 0.32 10.6 0.7 2.3 1 1 0 1 1 1 0 KR domain NAD_binding_10 PF13460.1 KFX96424.1 - 0.02 14.8 0.1 0.041 13.8 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding SKG6 PF08693.5 KFX96425.1 - 1.1e-09 37.4 0.2 2.2e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Gln-synt_C PF00120.19 KFX96426.1 - 7e-63 212.1 0.0 9.5e-63 211.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain adh_short PF00106.20 KFX96427.1 - 1.7e-27 96.3 2.8 2.3e-27 95.9 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX96427.1 - 2.4e-17 63.5 0.0 3.1e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX96427.1 - 2e-09 37.3 1.7 3e-09 36.7 1.2 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KFX96427.1 - 0.00015 21.4 0.1 0.00024 20.7 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_12 PF08242.7 KFX96427.1 - 0.00058 20.2 0.0 0.0013 19.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX96427.1 - 0.0012 19.4 0.0 0.01 16.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Epimerase PF01370.16 KFX96427.1 - 0.0034 16.8 0.1 0.0061 16.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFX96427.1 - 0.0046 15.9 0.0 0.0068 15.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_31 PF13847.1 KFX96427.1 - 0.064 12.8 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 KFX96427.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TPMT PF05724.6 KFX96427.1 - 0.097 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MoaC PF01967.16 KFX96427.1 - 0.1 12.2 0.3 0.59 9.7 0.0 2.1 1 1 1 2 2 2 0 MoaC family Eno-Rase_NADH_b PF12242.3 KFX96427.1 - 0.2 11.4 1.5 0.93 9.3 0.1 2.5 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HET PF06985.6 KFX96428.1 - 2.9e-21 76.0 0.0 5.3e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Scm3 PF10384.4 KFX96428.1 - 0.038 13.4 0.1 0.081 12.4 0.1 1.5 1 0 0 1 1 1 0 Centromere protein Scm3 ABC_tran PF00005.22 KFX96429.1 - 9e-48 162.0 0.1 1.9e-25 89.7 0.0 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFX96429.1 - 1.2e-15 58.2 3.3 0.0079 16.1 0.1 4.2 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 KFX96429.1 - 3.7e-12 45.9 0.5 0.0031 16.7 0.0 4.0 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KFX96429.1 - 1.1e-08 35.6 0.1 0.00072 19.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KFX96429.1 - 1.9e-08 33.6 1.1 0.005 16.3 0.3 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 KFX96429.1 - 3.4e-07 29.6 0.0 0.32 9.9 0.0 3.2 3 0 0 3 3 3 3 AAA ATPase domain DUF258 PF03193.11 KFX96429.1 - 2.3e-06 26.9 0.1 0.0078 15.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KFX96429.1 - 3.2e-06 27.0 0.4 0.15 12.0 0.0 3.2 3 0 0 3 3 2 2 50S ribosome-binding GTPase SbcCD_C PF13558.1 KFX96429.1 - 2.5e-05 24.0 0.0 0.39 10.6 0.0 3.1 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 KFX96429.1 - 2.8e-05 24.9 0.0 0.33 11.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KFX96429.1 - 6e-05 23.5 0.0 0.028 14.9 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein Chromo PF00385.19 KFX96429.1 - 0.0001 21.9 0.2 0.00023 20.7 0.1 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_28 PF13521.1 KFX96429.1 - 0.00038 20.4 0.0 0.027 14.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFX96429.1 - 0.00096 19.3 0.7 1.4 9.0 0.0 3.5 3 1 0 3 3 2 1 AAA domain AAA_10 PF12846.2 KFX96429.1 - 0.0012 18.3 2.2 1.2 8.4 0.1 3.6 4 1 0 4 4 4 2 AAA-like domain DUF87 PF01935.12 KFX96429.1 - 0.0021 17.9 0.7 0.42 10.3 0.1 3.0 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_13 PF13166.1 KFX96429.1 - 0.003 16.0 0.1 1 7.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain HEAT_2 PF13646.1 KFX96429.1 - 0.0074 16.5 6.0 0.89 9.8 0.1 3.7 1 1 2 3 3 3 1 HEAT repeats AAA_18 PF13238.1 KFX96429.1 - 0.0091 16.3 0.1 2.1 8.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 KFX96429.1 - 0.0092 15.8 0.0 0.6 9.9 0.0 3.0 3 0 0 3 3 3 1 Dynamin family PduV-EutP PF10662.4 KFX96429.1 - 0.017 14.6 0.1 4.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 KFX96429.1 - 0.023 14.5 0.0 3.4 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KFX96429.1 - 0.038 14.1 0.0 10 6.3 0.0 3.0 3 0 0 3 3 2 0 RNA helicase DUF3584 PF12128.3 KFX96429.1 - 0.038 11.3 2.6 1.7 5.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) ArgK PF03308.11 KFX96429.1 - 0.043 12.5 0.7 4 6.1 0.0 2.4 2 0 0 2 2 2 0 ArgK protein NACHT PF05729.7 KFX96429.1 - 0.044 13.4 0.5 3.9 7.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.8 KFX96429.1 - 0.066 12.1 0.1 7.8 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 KFX96429.1 - 0.097 11.7 0.3 11 5.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.9 KFX96429.1 - 0.1 12.2 0.3 17 5.1 0.2 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KFX96429.1 - 0.14 11.5 1.5 4.3 6.7 0.1 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_ATPase PF09818.4 KFX96429.1 - 0.27 9.7 3.6 22 3.4 0.0 3.4 3 0 0 3 3 3 0 Predicted ATPase of the ABC class ALF PF03752.8 KFX96429.1 - 0.64 9.9 3.7 1.7 8.5 1.5 2.4 2 0 0 2 2 2 0 Short repeats of unknown function HEAT PF02985.17 KFX96429.1 - 2 8.6 8.2 62 4.0 0.0 4.9 5 0 0 5 5 4 0 HEAT repeat DUF1275 PF06912.6 KFX96430.1 - 3.6e-44 150.4 9.8 4.7e-44 150.0 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MASE1 PF05231.9 KFX96430.1 - 0.0066 15.5 9.8 0.0086 15.1 1.5 2.1 2 0 0 2 2 2 2 MASE1 DUF3522 PF12036.3 KFX96430.1 - 0.055 13.2 0.8 0.091 12.5 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) DUF4131 PF13567.1 KFX96430.1 - 0.93 8.8 8.3 0.1 12.0 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Bax1-I PF01027.15 KFX96430.1 - 1.9 8.0 11.9 0.18 11.3 3.1 2.1 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Mid2 PF04478.7 KFX96432.1 - 9.3e-05 21.8 0.5 0.00022 20.6 0.3 1.6 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor NCU-G1 PF15065.1 KFX96432.1 - 0.00031 19.5 0.6 0.00054 18.7 0.4 1.3 1 0 0 1 1 1 1 Lysosomal transcription factor, NCU-G1 SKG6 PF08693.5 KFX96432.1 - 0.0008 18.6 4.1 0.0022 17.2 2.8 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 KFX96432.1 - 0.066 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Hydrophobin PF01185.13 KFX96433.1 - 2.2e-07 31.2 12.7 2.2e-07 31.2 8.8 1.8 2 1 0 2 2 2 1 Fungal hydrophobin Glyco_hydro_61 PF03443.9 KFX96434.1 - 1.4e-70 237.5 0.5 1.6e-70 237.3 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fibrinogen_C PF00147.13 KFX96434.1 - 0.071 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain ICL PF00463.16 KFX96435.1 - 5e-199 661.8 0.1 5.7e-199 661.6 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KFX96435.1 - 2.5e-11 43.2 0.1 1.7e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 KFX96435.1 - 0.033 13.6 0.0 0.078 12.4 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain DUF2458 PF10454.4 KFX96435.1 - 0.14 12.0 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) ubiquitin PF00240.18 KFX96439.1 - 3.1e-169 548.6 31.3 1.6e-33 113.9 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.3 KFX96439.1 - 3.6e-97 318.1 28.4 6.2e-19 67.4 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KFX96439.1 - 1.7e-29 101.9 15.8 0.00021 21.4 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KFX96439.1 - 7.5e-27 94.0 3.2 0.001 18.7 0.0 5.0 5 0 0 5 5 5 5 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KFX96439.1 - 6.2e-17 61.4 4.9 0.17 11.7 0.0 5.9 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KFX96439.1 - 1.1e-16 60.7 4.7 0.18 12.0 0.0 5.2 1 1 4 5 5 5 5 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 KFX96439.1 - 2.4e-13 49.9 0.0 2 8.4 0.0 5.9 5 0 0 5 5 5 5 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.9 KFX96439.1 - 7.7e-08 31.7 1.4 2.8 7.0 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase TUG-UBL1 PF11470.3 KFX96439.1 - 1.9e-07 30.8 9.3 6.3 6.7 0.0 5.2 5 0 0 5 5 5 5 GLUT4 regulating protein TUG FlgD_ig PF13860.1 KFX96439.1 - 1.6e-05 24.5 8.5 19 5.1 0.0 5.3 5 0 0 5 5 5 0 FlgD Ig-like domain Big_3_3 PF13750.1 KFX96439.1 - 0.00013 21.3 0.0 65 2.9 0.0 4.9 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 KFX96439.1 - 0.00032 19.1 18.9 3.1 5.9 0.2 6.7 6 4 0 6 6 6 4 Plexin cytoplasmic RasGAP domain ACT_4 PF13291.1 KFX96439.1 - 0.00038 20.7 1.5 1.4e+02 2.9 0.0 5.1 5 0 0 5 5 5 0 ACT domain CTDII PF01556.13 KFX96439.1 - 0.02 14.7 19.9 11 6.0 0.2 5.4 1 1 4 5 5 5 0 DnaJ C terminal domain Tash_PEST PF07708.6 KFX96439.1 - 0.025 14.4 38.3 4.5 7.3 1.2 5.4 5 0 0 5 5 5 0 Tash protein PEST motif GABP-alpha PF11620.3 KFX96439.1 - 0.058 13.3 11.8 63 3.6 0.1 5.0 5 0 0 5 5 5 0 GA-binding protein alpha chain FERM_N PF09379.5 KFX96439.1 - 0.13 12.3 17.1 58 3.8 0.1 7.0 5 5 0 5 5 5 0 FERM N-terminal domain DUF3781 PF12636.2 KFX96439.1 - 0.78 9.7 11.2 1.3e+02 2.5 0.1 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3781) Zn_clus PF00172.13 KFX96440.1 - 0.0068 16.2 7.7 0.0068 16.2 5.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Herpes_BMRF2 PF04633.7 KFX96440.1 - 0.37 9.6 0.0 0.59 9.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus BMRF2 protein Prenyltrans PF00432.16 KFX96441.1 - 3.9e-26 90.2 27.0 1.9e-06 27.3 0.3 5.8 5 1 1 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KFX96441.1 - 1.1e-17 64.4 0.1 3.7e-13 49.8 0.0 4.1 1 1 3 4 4 4 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 KFX96441.1 - 0.00013 21.8 0.3 0.00069 19.6 0.0 2.4 3 0 0 3 3 3 1 Prenyltransferase-like DND1_DSRM PF14709.1 KFX96442.1 - 0.00022 21.4 0.0 0.00042 20.5 0.0 1.5 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 KFX96442.1 - 0.00054 20.4 0.0 0.00091 19.7 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Pectate_lyase_3 PF12708.2 KFX96446.1 - 6.9e-88 294.5 26.0 1e-70 238.3 4.3 3.3 4 0 0 4 4 4 2 Pectate lyase superfamily protein WSC PF01822.14 KFX96446.1 - 1.4e-18 66.5 6.6 3.7e-18 65.2 4.6 1.8 1 0 0 1 1 1 1 WSC domain End_N_terminal PF12218.3 KFX96446.1 - 1.9e-07 30.4 3.4 0.0094 15.3 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Glyco_hydro_cc PF11790.3 KFX96447.1 - 1.5e-57 194.8 5.7 1.8e-57 194.5 4.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core WSC PF01822.14 KFX96447.1 - 1.3e-19 69.8 16.1 2.7e-19 68.8 6.6 2.6 2 0 0 2 2 2 2 WSC domain GSu_C4xC__C2xCH PF09698.5 KFX96447.1 - 0.001 19.2 1.0 0.008 16.3 0.7 2.7 1 0 0 1 1 1 1 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) DUF1996 PF09362.5 KFX96448.1 - 3.8e-49 167.4 0.8 6.3e-49 166.7 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 KFX96448.1 - 1.8e-17 63.0 12.8 5.1e-17 61.5 8.9 1.8 1 0 0 1 1 1 1 WSC domain Glyco_hydro_cc PF11790.3 KFX96449.1 - 2.1e-60 204.1 1.3 2.5e-60 203.8 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glycoprotein_B PF00606.13 KFX96450.1 - 0.041 11.9 3.5 0.046 11.7 2.4 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B DUF4233 PF14017.1 KFX96450.1 - 0.22 11.4 11.5 0.16 11.8 4.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4233) Tic20 PF09685.5 KFX96450.1 - 2.4 8.1 7.9 11 6.0 0.0 2.1 1 1 1 2 2 2 0 Tic20-like protein HATPase_c PF02518.21 KFX96452.1 - 2e-17 62.8 0.0 4.7e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KFX96452.1 - 2.2e-17 63.0 0.1 4.8e-17 61.9 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KFX96452.1 - 5.2e-15 55.1 0.5 1.8e-13 50.2 0.0 3.3 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Cyclin_N PF00134.18 KFX96475.1 - 2e-10 40.3 0.1 4.1e-10 39.3 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.6 KFX96475.1 - 9.4e-08 32.5 0.0 1.4e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin PRP21_like_P PF12230.3 KFX96477.1 - 7.2e-56 189.2 22.6 4.7e-55 186.6 15.7 2.0 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 KFX96477.1 - 9.1e-39 130.9 2.2 2e-18 65.7 0.2 2.6 2 0 0 2 2 2 2 Surp module PMT PF02366.13 KFX96478.1 - 2.8e-69 233.2 7.8 4.6e-69 232.4 5.4 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KFX96478.1 - 7.7e-54 182.1 0.0 1.2e-53 181.5 0.0 1.3 1 0 0 1 1 1 1 MIR domain Mito_carr PF00153.22 KFX96479.1 - 6.6e-74 243.7 2.1 2.4e-24 84.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PX PF00787.19 KFX96480.1 - 1.6e-23 82.6 0.0 3.8e-23 81.4 0.0 1.7 1 0 0 1 1 1 1 PX domain Sec2p PF06428.6 KFX96480.1 - 6.6e-22 77.2 16.2 6.6e-22 77.2 11.2 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p V_ATPase_I PF01496.14 KFX96480.1 - 0.088 10.6 7.7 0.13 10.1 5.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Methyltransf_21 PF05050.7 KFX96480.1 - 0.16 11.9 0.3 0.54 10.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase FkbM domain DUF310 PF03750.8 KFX96480.1 - 1.1 9.4 6.2 3.1 8.0 4.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF310) DUF4407 PF14362.1 KFX96480.1 - 1.9 7.3 9.0 4.2 6.2 6.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MBA1 PF07961.6 KFX96481.1 - 4.3e-18 65.0 0.0 5.7e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.10 KFX96481.1 - 7.3e-07 29.2 0.4 1.5e-06 28.2 0.1 1.7 2 0 0 2 2 2 1 Tim44-like domain RRM_1 PF00076.17 KFX96483.1 - 5.1e-25 86.8 0.9 4.1e-11 42.3 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX96483.1 - 7e-14 51.5 0.6 7.4e-07 29.0 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX96483.1 - 4.6e-11 42.4 0.6 0.0002 21.1 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFX96483.1 - 0.012 15.3 0.4 12 5.7 0.0 3.4 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KFX96483.1 - 0.043 13.6 0.0 0.53 10.1 0.0 2.6 3 0 0 3 3 3 0 RNA binding motif E1-E2_ATPase PF00122.15 KFX96486.1 - 2.1e-38 131.6 10.9 2.1e-38 131.6 7.6 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KFX96486.1 - 8.2e-30 104.8 0.0 1.5e-29 103.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFX96486.1 - 8.8e-16 58.6 0.0 1.8e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KFX96486.1 - 1.8e-06 27.9 0.0 7.9e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 KFX96486.1 - 5.2e-05 22.9 0.2 0.0086 15.6 0.1 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase SNF2_N PF00176.18 KFX96487.1 - 4.5e-72 242.3 0.0 5.9e-72 241.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KFX96487.1 - 2.8e-26 91.5 0.0 6.9e-26 90.2 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 KFX96487.1 - 1.3e-11 44.2 0.0 2.8e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 KFX96487.1 - 7.6e-07 29.0 8.1 1.4e-06 28.1 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 KFX96487.1 - 8.2e-06 25.7 0.0 2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 KFX96487.1 - 5.5e-05 22.7 8.0 0.0001 21.8 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFX96487.1 - 0.00035 20.1 5.6 0.00064 19.3 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFX96487.1 - 0.0016 18.2 7.5 0.0032 17.2 5.2 1.5 1 0 0 1 1 1 1 Ring finger domain ACT_3 PF10000.4 KFX96487.1 - 0.0062 16.2 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 ACT domain AAA_22 PF13401.1 KFX96487.1 - 0.012 15.8 0.0 0.17 12.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain zf-RING_5 PF14634.1 KFX96487.1 - 0.039 13.6 7.1 0.14 11.8 5.1 1.9 1 1 1 2 2 2 0 zinc-RING finger domain UBA_4 PF14555.1 KFX96487.1 - 0.057 12.9 0.1 0.17 11.4 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain SQS_PSY PF00494.14 KFX96488.1 - 1.1e-47 162.5 0.0 1.7e-47 161.9 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase CorA PF01544.13 KFX96489.1 - 1.7e-30 106.1 11.6 8.1e-20 71.0 2.4 3.1 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein DUF503 PF04456.7 KFX96489.1 - 0.044 13.3 0.1 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF503) DUF1516 PF07457.6 KFX96489.1 - 0.12 12.4 0.8 0.22 11.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1516) DUF1191 PF06697.7 KFX96489.1 - 0.13 11.0 0.1 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Yos1 PF08571.5 KFX96496.1 - 1.1e-30 105.5 0.2 1.2e-30 105.4 0.2 1.0 1 0 0 1 1 1 1 Yos1-like Fungal_trans PF04082.13 KFX96499.1 - 9.7e-25 86.9 0.1 1.6e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX96499.1 - 6e-08 32.4 13.7 1.1e-07 31.5 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Shugoshin_N PF07558.6 KFX96499.1 - 0.01 15.5 0.7 0.02 14.5 0.5 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region SNAPc19 PF15497.1 KFX96499.1 - 0.051 13.7 0.4 0.096 12.8 0.3 1.4 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 TSC22 PF01166.13 KFX96499.1 - 0.17 11.9 0.6 0.33 10.9 0.4 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Dor1 PF04124.7 KFX96505.1 - 8.6e-53 178.9 0.7 1.4e-41 142.1 1.8 2.1 2 0 0 2 2 2 2 Dor1-like family YjcZ PF13990.1 KFX96505.1 - 0.0095 15.0 3.9 0.67 9.0 0.5 2.9 3 0 0 3 3 3 2 YjcZ-like protein Cellulase-like PF12876.2 KFX96505.1 - 0.34 11.4 2.5 1.7 9.1 0.0 3.1 4 0 0 4 4 4 0 Sugar-binding cellulase-like MS_channel PF00924.13 KFX96511.1 - 3e-23 82.2 1.9 5.9e-23 81.2 1.3 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KFX96511.1 - 0.00036 19.6 0.6 0.00099 18.2 0.4 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KFX96511.1 - 0.0009 18.9 0.1 0.0035 17.0 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 KFX96511.1 - 0.0015 17.8 0.1 0.0041 16.4 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KFX96511.1 - 0.0044 17.1 0.1 0.013 15.6 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair DAO PF01266.19 KFX96512.1 - 3.4e-39 134.7 0.0 3.9e-39 134.5 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFX96512.1 - 0.00042 20.2 0.0 0.035 13.9 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFX96512.1 - 0.00096 18.1 0.0 0.027 13.3 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KFX96512.1 - 0.027 14.2 0.1 3.1 7.5 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding GMC_oxred_N PF00732.14 KFX96512.1 - 0.038 13.1 0.1 0.082 12.0 0.0 1.5 2 0 0 2 2 2 0 GMC oxidoreductase NAD_binding_8 PF13450.1 KFX96512.1 - 0.055 13.5 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Saccharop_dh PF03435.13 KFX96512.1 - 0.061 12.2 0.0 0.095 11.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase HI0933_like PF03486.9 KFX96512.1 - 0.14 10.5 0.0 0.5 8.7 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein DUF3779 PF12621.3 KFX96514.1 - 1.2e-12 47.5 0.0 1.5e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Phosphate metabolism protein HSP70 PF00012.15 KFX96515.1 - 2.9e-08 32.0 0.3 1.7e-05 22.9 0.1 2.4 2 1 0 2 2 2 2 Hsp70 protein Peptidase_M22 PF00814.20 KFX96515.1 - 0.051 13.0 0.0 0.098 12.1 0.0 1.4 2 0 0 2 2 2 0 Glycoprotease family DUF2875 PF11394.3 KFX96515.1 - 0.1 11.1 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2875) BacteriocIIc_cy PF12173.3 KFX96516.1 - 0.09 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacteriocin class IIc cyclic gassericin A-like Dynamin_N PF00350.18 KFX96517.1 - 3.1e-26 92.1 0.5 1.3e-25 90.1 0.0 2.1 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KFX96517.1 - 1.3e-16 60.2 3.3 2.3e-14 52.8 0.0 3.1 3 0 0 3 3 3 2 Dynamin central region MMR_HSR1 PF01926.18 KFX96517.1 - 0.0026 17.6 0.1 0.016 15.1 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 KFX96517.1 - 0.0029 17.4 0.8 0.012 15.5 0.1 2.4 2 1 1 3 3 3 1 Dynamin GTPase effector domain Miro PF08477.8 KFX96517.1 - 0.012 16.1 0.0 0.045 14.2 0.0 2.1 1 0 0 1 1 1 0 Miro-like protein HsbA PF12296.3 KFX96520.1 - 0.00064 19.5 2.0 0.001 18.9 0.6 2.0 1 1 1 2 2 2 1 Hydrophobic surface binding protein A DUF3584 PF12128.3 KFX96520.1 - 0.00065 17.1 15.1 0.001 16.5 10.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Laminin_II PF06009.7 KFX96520.1 - 0.001 18.8 1.8 0.001 18.8 1.3 2.3 1 1 2 3 3 3 1 Laminin Domain II Prominin PF05478.6 KFX96520.1 - 0.001 16.6 6.4 0.0013 16.4 4.4 1.1 1 0 0 1 1 1 1 Prominin MscS_porin PF12795.2 KFX96520.1 - 0.0013 18.1 13.5 0.0013 18.1 9.4 1.5 1 1 0 1 1 1 1 Mechanosensitive ion channel porin domain AAA_13 PF13166.1 KFX96520.1 - 0.0018 16.8 4.7 0.0018 16.8 3.3 1.9 1 1 1 2 2 2 1 AAA domain DUF1664 PF07889.7 KFX96520.1 - 0.006 16.3 15.4 0.55 10.0 3.7 3.1 1 1 1 3 3 3 2 Protein of unknown function (DUF1664) DUF876 PF05936.7 KFX96520.1 - 0.01 14.3 0.5 0.016 13.6 0.3 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF876) DUF3376 PF11856.3 KFX96520.1 - 0.017 14.5 3.2 0.02 14.3 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3376) TPR_MLP1_2 PF07926.7 KFX96520.1 - 0.021 14.5 20.7 0.028 14.1 2.4 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF2968 PF11180.3 KFX96520.1 - 0.028 13.8 9.9 0.027 13.8 6.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) Tropomyosin PF00261.15 KFX96520.1 - 0.034 13.2 18.4 0.062 12.3 11.2 2.1 1 1 1 2 2 2 0 Tropomyosin Atg14 PF10186.4 KFX96520.1 - 0.048 12.5 15.3 0.027 13.4 9.4 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 KFX96520.1 - 0.054 13.0 23.8 0.47 10.0 4.0 2.1 1 1 1 2 2 2 0 IncA protein CALCOCO1 PF07888.6 KFX96520.1 - 0.072 11.3 15.5 0.1 10.8 10.7 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like EzrA PF06160.7 KFX96520.1 - 0.085 11.0 11.7 0.11 10.6 8.1 1.3 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Sec8_exocyst PF04048.9 KFX96520.1 - 0.13 11.9 13.9 0.2 11.2 1.1 3.3 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain Prp19 PF08606.6 KFX96520.1 - 0.18 11.5 2.6 4.9 6.9 0.0 2.5 1 1 1 2 2 2 0 Prp19/Pso4-like Spc7 PF08317.6 KFX96520.1 - 0.18 10.4 17.1 0.089 11.4 10.3 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF3461 PF11944.3 KFX96520.1 - 0.18 11.6 12.2 3.1 7.6 0.4 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF3461) HrpB7 PF09486.5 KFX96520.1 - 0.2 11.5 11.5 0.56 10.1 1.0 2.8 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) IFT57 PF10498.4 KFX96520.1 - 0.3 9.8 14.9 0.027 13.1 5.4 1.9 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 HAUS-augmin3 PF14932.1 KFX96520.1 - 0.31 10.1 15.2 0.44 9.6 10.2 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Thioesterase PF00975.15 KFX96520.1 - 0.38 10.9 1.9 0.55 10.4 0.7 1.5 1 1 1 2 2 2 0 Thioesterase domain Nup54 PF13874.1 KFX96520.1 - 0.42 10.2 13.4 2.2 7.9 4.8 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 COG2 PF06148.6 KFX96520.1 - 0.65 9.8 13.9 0.12 12.2 1.2 3.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Seryl_tRNA_N PF02403.17 KFX96520.1 - 0.81 9.7 19.5 1.7 8.7 2.0 2.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF1525 PF07511.6 KFX96520.1 - 1.1 9.2 3.5 0.91 9.5 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1525) CENP-F_leu_zip PF10473.4 KFX96520.1 - 1.3 8.9 22.9 0.022 14.5 6.5 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.9 KFX96520.1 - 1.4 8.5 16.1 18 4.9 11.2 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Baculo_PEP_C PF04513.7 KFX96520.1 - 1.6 8.5 5.0 0.99 9.2 0.2 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_TATA_bd PF12325.3 KFX96520.1 - 1.7 8.3 19.2 1.7 8.4 3.8 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Occludin_ELL PF07303.8 KFX96520.1 - 1.9 9.2 11.1 6.3 7.6 3.2 2.8 1 1 1 2 2 2 0 Occludin homology domain BRE1 PF08647.6 KFX96520.1 - 2 8.4 15.5 1.6 8.7 6.6 3.0 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase ATG16 PF08614.6 KFX96520.1 - 2.1 8.1 23.4 1.5 8.5 5.9 2.7 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Peptidase_S46 PF10459.4 KFX96520.1 - 2.1 6.6 13.4 4.6 5.5 2.7 1.9 1 1 1 2 2 2 0 Peptidase S46 DUF3391 PF11871.3 KFX96520.1 - 2.3 8.4 9.2 23 5.2 5.8 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) APG6 PF04111.7 KFX96520.1 - 2.5 7.0 21.3 0.32 9.9 7.1 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 SYCE1 PF15233.1 KFX96520.1 - 2.6 7.9 17.3 0.87 9.5 5.9 3.2 1 1 2 3 3 3 0 Synaptonemal complex central element protein 1 DUF948 PF06103.6 KFX96520.1 - 2.9 7.8 5.7 1.1 9.1 0.2 2.6 1 1 2 3 3 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.7 KFX96520.1 - 3.3 8.0 6.6 1.8 8.8 0.3 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 KFX96520.1 - 3.5 6.7 9.5 0.26 10.4 1.0 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ADIP PF11559.3 KFX96520.1 - 6 6.7 21.2 0.63 9.9 6.1 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 KFX96520.1 - 6.5 7.1 14.4 2.5 8.5 4.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 KFX96520.1 - 7.6 4.2 15.8 22 2.7 10.9 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 KFX96520.1 - 7.6 6.6 12.7 0.98 9.5 1.7 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family HhH-GPD PF00730.20 KFX96521.1 - 0.059 13.6 0.0 0.076 13.3 0.0 1.5 1 1 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein OTT_1508_deam PF14441.1 KFX96522.1 - 1.4e-05 24.9 0.0 3.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase TAFH PF07531.9 KFX96522.1 - 0.025 14.1 0.3 0.1 12.2 0.1 2.2 2 1 0 2 2 2 0 NHR1 homology to TAF Dynamin_N PF00350.18 KFX96523.1 - 2.5e-08 33.9 0.1 6.4e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 KFX96523.1 - 0.00055 20.4 0.0 0.0014 19.0 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 KFX96523.1 - 0.022 14.7 0.1 0.23 11.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KFX96523.1 - 0.03 14.6 0.5 0.092 13.0 0.1 2.0 2 0 0 2 2 2 0 ABC transporter SE PF08491.5 KFX96524.1 - 2.4e-92 308.6 0.0 4.3e-92 307.8 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 KFX96524.1 - 3.5e-10 39.4 0.0 5.7e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KFX96524.1 - 1.1e-08 34.6 0.0 1.8e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 KFX96524.1 - 4.1e-08 32.5 0.0 7.8e-07 28.3 0.1 2.9 4 0 0 4 4 4 1 FAD dependent oxidoreductase GIDA PF01134.17 KFX96524.1 - 4.5e-06 25.7 0.2 0.00071 18.5 0.2 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KFX96524.1 - 2.7e-05 23.1 1.8 3e-05 23.0 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain PPR_3 PF13812.1 KFX96524.1 - 0.00031 20.8 0.1 3.5 8.1 0.0 5.8 6 0 0 6 6 5 1 Pentatricopeptide repeat domain Thi4 PF01946.12 KFX96524.1 - 0.00045 19.3 0.0 0.0011 18.0 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KFX96524.1 - 0.00053 19.9 0.1 0.00098 19.0 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX96524.1 - 0.00064 19.6 0.3 0.002 18.1 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain PPR_2 PF13041.1 KFX96524.1 - 0.0011 18.8 0.1 0.0053 16.6 0.0 2.3 2 0 0 2 2 2 1 PPR repeat family 3HCDH_N PF02737.13 KFX96524.1 - 0.0064 16.1 0.1 0.015 14.9 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KFX96524.1 - 0.0072 14.8 0.2 0.013 13.9 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 KFX96524.1 - 0.01 14.4 0.1 0.85 8.1 0.2 3.0 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox PF00070.22 KFX96524.1 - 0.01 16.1 0.4 0.036 14.4 0.1 2.1 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFX96524.1 - 0.11 11.3 0.4 0.88 8.4 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein ThiF PF00899.16 KFX96524.1 - 0.22 11.3 0.3 0.55 10.0 0.2 1.7 1 0 0 1 1 1 0 ThiF family Glycos_transf_2 PF00535.21 KFX96525.1 - 4.4e-20 72.0 0.0 6.7e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KFX96525.1 - 5e-09 36.3 0.3 1.6e-05 24.8 0.0 2.4 2 1 0 2 2 2 2 Glycosyltransferase like family 2 SUN PF03856.8 KFX96527.1 - 1e-78 264.0 12.9 1.3e-78 263.7 8.9 1.0 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) LCM PF04072.9 KFX96528.1 - 6.1e-26 91.1 0.0 8.1e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase TFIID-18kDa PF02269.11 KFX96529.1 - 6.4e-31 106.0 1.0 2.5e-30 104.1 0.0 2.3 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit GFA PF04828.9 KFX96530.1 - 8.2e-09 35.2 1.3 1.6e-05 24.7 0.0 2.3 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Lar_restr_allev PF14354.1 KFX96530.1 - 0.092 13.0 0.5 0.36 11.1 0.0 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar SET PF00856.23 KFX96531.1 - 1.9e-09 38.0 0.0 5.4e-06 26.8 0.0 2.7 2 0 0 2 2 2 2 SET domain Apc3 PF12895.2 KFX96531.1 - 0.00029 20.9 0.2 0.00071 19.6 0.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 KFX96531.1 - 0.0016 18.0 4.7 0.0096 15.5 0.2 3.0 2 1 2 4 4 4 1 TPR repeat TPR_19 PF14559.1 KFX96531.1 - 0.0016 18.7 0.4 0.013 15.8 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFX96531.1 - 0.016 14.7 2.4 0.96 9.1 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1955 PF09205.5 KFX96531.1 - 0.018 14.5 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1955) TPR_16 PF13432.1 KFX96531.1 - 0.1 13.3 5.7 1.1 10.0 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFX96531.1 - 0.15 12.7 3.7 73 4.4 0.1 4.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFX96531.1 - 0.87 9.6 6.1 12 6.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat UCH PF00443.24 KFX96565.1 - 1.2e-37 129.4 0.0 4.5e-37 127.6 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 KFX96565.1 - 4.5e-32 109.2 2.4 1.2e-12 47.0 0.2 4.4 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.1 KFX96565.1 - 9.5e-15 54.7 2.1 1.1e-06 28.2 0.0 3.1 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Tim17 PF02466.14 KFX96566.1 - 2.7e-14 53.3 9.5 3.9e-14 52.7 6.6 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TBCC PF07986.7 KFX96567.1 - 1.6e-34 117.8 0.5 2.9e-34 117.0 0.3 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C K-box PF01486.12 KFX96567.1 - 0.11 12.3 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 K-box region DUF3505 PF12013.3 KFX96569.1 - 2.6e-13 50.1 0.0 1.1e-06 28.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3505) DUF3505 PF12013.3 KFX96570.1 - 9.5e-14 51.5 0.2 2.5e-13 50.2 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) SH3_4 PF06347.8 KFX96580.1 - 0.079 12.5 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain Fungal_trans_2 PF11951.3 KFX96581.1 - 3e-06 26.1 0.1 4.7e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KFX96582.1 - 2.2e-34 118.7 58.2 2.7e-33 115.1 36.8 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX96582.1 - 3e-10 39.2 8.6 3e-10 39.2 5.9 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 KFX96582.1 - 0.00073 18.0 6.2 0.00073 18.0 4.3 3.1 3 1 0 3 3 3 1 MFS/sugar transport protein PI3_PI4_kinase PF00454.22 KFX96586.1 - 3e-42 144.7 0.0 2.4e-40 138.5 0.0 2.8 2 1 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KFX96586.1 - 4e-23 81.5 0.1 3.6e-22 78.4 0.0 2.3 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Proteasome PF00227.21 KFX96587.1 - 9.6e-29 100.0 0.2 1.8e-28 99.1 0.1 1.4 1 1 0 1 1 1 1 Proteasome subunit Zn_clus PF00172.13 KFX96613.1 - 1.8e-08 34.1 15.1 3.2e-08 33.3 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EF-hand_4 PF12763.2 KFX96613.1 - 0.08 12.6 0.0 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Phage_tail_T PF06223.7 KFX96615.1 - 0.0026 18.1 11.4 0.75 10.2 0.1 3.4 1 1 1 3 3 3 3 Minor tail protein T BBP1_C PF15272.1 KFX96616.1 - 0.021 14.3 1.4 0.023 14.2 0.0 1.7 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Acyl-CoA_dh_1 PF00441.19 KFX96617.1 - 2.6e-43 147.7 1.4 2.6e-43 147.7 1.0 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFX96617.1 - 2.1e-30 105.5 0.1 5.9e-30 104.1 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KFX96617.1 - 1.5e-20 72.4 0.2 3.1e-20 71.4 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFX96617.1 - 1e-15 58.1 0.2 2.4e-15 56.9 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KFX96617.1 - 0.017 14.5 0.4 0.084 12.2 0.3 2.0 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Carboxyl_trans PF01039.17 KFX96618.1 - 5.5e-142 473.5 0.1 7.3e-142 473.1 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Bot1p PF12298.3 KFX96619.1 - 5.8e-52 176.0 0.8 1e-51 175.2 0.6 1.4 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein DUF2052 PF09747.4 KFX96619.1 - 2e-34 119.0 0.6 4.1e-34 118.0 0.4 1.5 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Y_phosphatase3 PF13350.1 KFX96620.1 - 7.5e-44 149.8 0.0 2.1e-43 148.4 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KFX96620.1 - 2.4e-15 56.3 0.0 2.3e-14 53.2 0.0 2.3 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 KFX96620.1 - 2.9e-05 23.5 0.0 4.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 KFX96620.1 - 0.0018 17.6 0.0 0.0035 16.7 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family HTH_Tnp_1 PF01527.15 KFX96620.1 - 0.043 13.7 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 Transposase DUF3752 PF12572.3 KFX96639.1 - 1.2e-40 139.1 6.4 1.2e-40 139.1 4.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) E1_dh PF00676.15 KFX96639.1 - 0.044 12.5 0.0 0.068 11.8 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component FA_desaturase PF00487.19 KFX96648.1 - 2.1e-17 63.4 7.1 3e-17 62.9 4.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KFX96648.1 - 0.00029 20.8 0.0 0.00068 19.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) RuBisCO_large_N PF02788.11 KFX96648.1 - 0.28 10.8 1.2 0.47 10.1 0.8 1.4 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain TAT_signal PF10518.4 KFX96648.1 - 0.4 10.8 4.1 1 9.5 2.8 1.8 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence DUF2615 PF11027.3 KFX96649.1 - 0.061 13.2 0.0 0.065 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Inhibitor_I53 PF11714.3 KFX96649.1 - 0.064 13.2 0.1 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Thrombin inhibitor Madanin Flagellin_IN PF07196.8 KFX96653.1 - 0.091 12.7 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Flagellin hook IN motif FMO-like PF00743.14 KFX96655.1 - 5.7e-61 206.3 0.0 7e-61 206.0 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFX96655.1 - 3.8e-28 98.9 0.0 2e-27 96.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFX96655.1 - 9.2e-10 38.7 0.0 1.4e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFX96655.1 - 3.4e-09 36.0 0.0 6.4e-08 31.8 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KFX96655.1 - 3.9e-06 26.7 0.0 0.0002 21.1 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KFX96655.1 - 0.00018 21.8 0.2 0.28 11.6 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.7 KFX96655.1 - 0.00027 20.3 0.0 0.073 12.4 0.0 2.3 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 KFX96655.1 - 0.00065 18.9 0.2 0.18 10.9 0.1 2.4 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KFX96655.1 - 0.0017 18.2 0.4 0.0091 15.8 0.1 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_8 PF13450.1 KFX96655.1 - 0.0027 17.6 0.0 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFX96655.1 - 0.0044 15.9 0.0 2 7.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KFX96655.1 - 0.014 15.6 0.0 5.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 KFX96655.1 - 0.03 13.6 0.0 0.067 12.5 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Peptidase_M17_N PF02789.12 KFX96655.1 - 0.13 12.0 0.1 11 5.7 0.0 2.2 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain GTP_EFTU PF00009.22 KFX96656.1 - 1.8e-52 177.5 0.0 2.9e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KFX96656.1 - 7.9e-14 51.3 0.0 2e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KFX96656.1 - 3e-09 36.5 0.0 6.4e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KFX96656.1 - 1.2e-08 34.8 0.0 1.6e-07 31.3 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 KFX96656.1 - 2.3e-05 23.9 0.0 0.00011 21.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV PH PF00169.24 KFX96657.1 - 1.8e-13 50.5 0.2 2.7e-13 50.0 0.1 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KFX96657.1 - 2.8e-06 27.5 0.1 1.6e-05 25.1 0.1 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KFX96657.1 - 5.6e-06 26.3 0.1 9.3e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 KFX96657.1 - 3.3e-05 24.0 0.1 0.0012 19.0 0.1 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 KFX96657.1 - 8.9e-05 22.3 0.1 0.00014 21.6 0.1 1.3 1 0 0 1 1 1 1 PH domain DUF4148 PF13663.1 KFX96659.1 - 2.3 8.1 5.4 8.1 6.3 3.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4148) TB2_DP1_HVA22 PF03134.14 KFX96664.1 - 8.5e-27 92.7 8.2 1.5e-26 91.9 5.7 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family HTH_Tnp_Tc5 PF03221.11 KFX96665.1 - 7.7e-06 25.6 0.2 1.6e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Sigma70_r4 PF04545.11 KFX96665.1 - 0.011 14.9 0.0 0.027 13.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_4 PF13613.1 KFX96665.1 - 0.095 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease DUF1013 PF06242.6 KFX96665.1 - 0.11 12.5 0.2 0.25 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1013) HTH_23 PF13384.1 KFX96665.1 - 0.12 12.1 0.0 0.41 10.3 0.0 1.9 1 0 0 1 1 1 0 Homeodomain-like domain CENP-B_N PF04218.8 KFX96665.1 - 0.33 10.4 0.0 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain XRN_N PF03159.13 KFX96668.1 - 3e-103 344.3 0.1 4.7e-103 343.6 0.1 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus WD40 PF00400.27 KFX96669.1 - 2.5e-40 134.9 4.2 9.1e-10 38.0 0.3 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KFX96669.1 - 2.4e-30 104.2 1.1 5.9e-30 102.9 0.8 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Peptidase_C93 PF06035.6 KFX96670.1 - 0.094 12.1 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP Med5 PF08689.5 KFX96676.1 - 1.3e-179 599.0 0.0 1.6e-179 598.8 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 DUF3534 PF12053.3 KFX96676.1 - 0.0037 17.1 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3534) ORC5_C PF14630.1 KFX96677.1 - 1.9e-71 240.7 0.0 2.3e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus CLTH PF10607.4 KFX96683.1 - 6.4e-33 113.4 0.1 1.6e-32 112.1 0.0 1.7 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Pyr_redox_2 PF07992.9 KFX96683.1 - 2.4e-21 76.5 0.0 3.5e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX96683.1 - 4.4e-14 52.6 0.0 1.7e-10 41.1 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase LisH PF08513.6 KFX96683.1 - 1.6e-07 30.8 0.0 2.9e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 LisH EF-hand_1 PF00036.27 KFX96683.1 - 1e-05 24.4 0.3 2.3e-05 23.3 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KFX96683.1 - 0.00021 20.8 0.3 0.00062 19.4 0.2 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 KFX96683.1 - 0.0003 20.8 0.1 0.001 19.1 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KFX96683.1 - 0.00037 19.6 0.4 0.00078 18.6 0.3 1.6 1 0 0 1 1 1 1 EF hand Pyr_redox_3 PF13738.1 KFX96683.1 - 0.014 15.4 0.1 7 6.6 0.0 2.9 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Toprim PF01751.17 KFX96683.1 - 0.094 12.7 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 Toprim domain PAT1 PF09770.4 KFX96684.1 - 4.4 5.4 7.1 3.9 5.5 4.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2313 PF10076.4 KFX96685.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2313) Methyltransf_2 PF00891.13 KFX96686.1 - 6.6e-30 104.0 0.0 9.6e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase TrmB PF01978.14 KFX96686.1 - 0.0021 17.7 0.0 0.0038 16.8 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Dimerisation PF08100.6 KFX96686.1 - 0.018 14.8 0.2 0.14 12.0 0.0 2.6 2 0 0 2 2 2 0 Dimerisation domain HTH_24 PF13412.1 KFX96686.1 - 0.018 14.3 0.1 0.041 13.2 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding NinB PF05772.7 KFX96686.1 - 0.027 14.1 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 NinB protein Rrf2 PF02082.15 KFX96686.1 - 0.031 14.3 0.1 0.16 12.1 0.0 2.2 2 1 0 2 2 2 0 Transcriptional regulator Fungal_trans PF04082.13 KFX96687.1 - 4.3e-08 32.3 0.0 6.7e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_28 PF00295.12 KFX96688.1 - 6.8e-88 294.7 19.5 8.4e-88 294.4 13.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 KFX96688.1 - 0.0002 21.1 19.5 0.0002 21.1 13.5 2.0 2 1 0 2 2 2 1 Right handed beta helix region MFS_1 PF07690.11 KFX96689.1 - 4.2e-45 154.0 57.0 2.5e-44 151.4 38.2 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFX96689.1 - 1.4e-23 83.0 27.4 2e-23 82.4 19.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KFX96689.1 - 4.9e-13 48.4 17.4 4.9e-13 48.4 12.1 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter Prenyltransf PF01255.14 KFX96690.1 - 1.3e-75 253.3 0.0 2.7e-72 242.5 0.0 3.3 3 1 0 3 3 3 2 Putative undecaprenyl diphosphate synthase DUF2420 PF10336.4 KFX96690.1 - 0.011 15.2 0.0 0.034 13.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2420) Terpene_synth_C PF03936.11 KFX96691.1 - 0.022 14.0 0.0 0.064 12.4 0.0 1.7 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain ANTAR PF03861.9 KFX96691.1 - 0.045 13.3 0.0 0.092 12.3 0.0 1.4 1 0 0 1 1 1 0 ANTAR domain ADSL_C PF10397.4 KFX96691.1 - 0.096 12.7 0.1 0.41 10.6 0.0 2.0 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminus Crystall_3 PF08964.5 KFX96693.1 - 1.9e-05 24.2 0.4 0.025 14.2 0.0 3.2 3 0 0 3 3 3 2 Beta/Gamma crystallin Crystall PF00030.14 KFX96693.1 - 0.003 17.4 0.3 1 9.2 0.0 3.0 3 0 0 3 3 3 2 Beta/Gamma crystallin DUF2946 PF11162.3 KFX96693.1 - 4.5 7.5 6.4 37 4.5 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2946) DUF2667 PF10868.3 KFX96702.1 - 0.027 14.8 0.2 0.037 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2667) Sugar_tr PF00083.19 KFX96725.1 - 2.6e-45 154.8 2.8 3.4e-45 154.4 1.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX96725.1 - 2e-31 109.0 25.3 3.4e-31 108.2 17.5 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.3 KFX96725.1 - 0.00077 18.0 17.5 0.0023 16.4 6.3 2.3 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 KFX96725.1 - 0.0033 17.1 0.1 3.9 7.3 0.0 2.8 2 0 0 2 2 2 2 MFS_1 like family OATP PF03137.15 KFX96725.1 - 0.17 9.8 1.4 0.15 10.0 0.1 1.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family LacY_symp PF01306.14 KFX96725.1 - 0.59 8.6 6.9 3.4 6.1 4.3 2.1 1 1 0 1 1 1 0 LacY proton/sugar symporter DUF2236 PF09995.4 KFX96726.1 - 6e-31 107.5 0.0 8e-31 107.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF2520 PF10728.4 KFX96726.1 - 0.06 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) Ank_2 PF12796.2 KFX96728.1 - 2e-99 326.1 14.5 7.9e-20 71.0 0.0 5.4 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KFX96728.1 - 8.1e-66 214.7 20.3 2.3e-05 23.9 0.0 13.2 11 2 2 13 13 13 12 Ankyrin repeat Ank_3 PF13606.1 KFX96728.1 - 4.2e-55 178.2 4.3 0.00013 21.8 0.0 13.3 11 2 2 13 13 13 11 Ankyrin repeat Ank_4 PF13637.1 KFX96728.1 - 2.3e-54 180.8 5.4 1.3e-10 41.5 0.0 10.2 2 2 11 13 13 13 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX96728.1 - 3.5e-43 144.6 15.2 2.6e-08 33.8 0.2 12.0 1 1 12 13 13 13 11 Ankyrin repeats (many copies) DUF4646 PF15496.1 KFX96728.1 - 1e-06 28.8 0.3 7.8e-06 25.9 0.2 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) DUF1843 PF08898.5 KFX96728.1 - 0.0053 16.7 0.2 30 4.7 0.0 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) Shigella_OspC PF06128.6 KFX96728.1 - 0.034 13.6 3.7 17 4.7 0.0 5.4 7 1 1 8 8 8 0 Shigella flexneri OspC protein DUF249 PF03158.8 KFX96728.1 - 0.04 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Multigene family 530 protein Abhydrolase_5 PF12695.2 KFX96729.1 - 0.0033 17.2 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX96729.1 - 0.0059 16.5 0.0 0.0062 16.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KFX96729.1 - 0.14 11.7 0.2 0.37 10.3 0.0 1.9 2 1 0 2 2 2 0 Lipase (class 3) PHY PF00360.15 KFX96730.1 - 1.3e-25 89.5 0.0 3.3e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 KFX96730.1 - 3.4e-19 68.5 0.2 7.7e-19 67.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KFX96730.1 - 2.3e-17 63.0 0.0 1.5e-16 60.4 0.0 2.3 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.21 KFX96730.1 - 5.5e-17 62.3 0.0 1.1e-16 61.3 0.0 1.6 1 0 0 1 1 1 1 GAF domain HisKA PF00512.20 KFX96730.1 - 3.2e-13 49.4 0.5 1e-12 47.8 0.3 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 KFX96730.1 - 3.3e-07 30.7 0.0 1.2e-06 28.8 0.0 2.1 2 0 0 2 2 2 1 PAS fold Pedibin PF08182.6 KFX96730.1 - 0.11 12.0 0.1 24 4.5 0.0 2.7 2 0 0 2 2 2 0 Pedibin/Hym-346 family WSC PF01822.14 KFX96732.1 - 1.7e-30 104.7 18.2 1.5e-17 63.2 4.3 3.5 3 0 0 3 3 3 2 WSC domain Ank_2 PF12796.2 KFX96733.1 - 4.1e-12 46.2 0.1 2.1e-09 37.5 0.0 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFX96733.1 - 1.4e-11 43.5 1.2 0.0031 17.2 0.0 4.3 3 1 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KFX96733.1 - 3.3e-09 37.0 0.1 7.2e-08 32.7 0.0 3.0 2 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX96733.1 - 1e-07 31.4 0.5 0.37 11.1 0.0 5.1 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 KFX96733.1 - 2.1e-05 24.5 0.0 0.017 15.3 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DUF4231 PF14015.1 KFX96733.1 - 2.7 8.0 0.0 2.7 8.0 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) DUF2956 PF11169.3 KFX96734.1 - 0.092 12.7 0.8 0.13 12.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) DUF1961 PF09224.6 KFX96739.1 - 2.8e-82 275.0 0.0 3.4e-82 274.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1961) Sugar_tr PF00083.19 KFX96740.1 - 1.1e-66 225.2 30.3 1.3e-66 225.0 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX96740.1 - 4.1e-14 52.0 30.8 4.1e-14 52.0 21.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Dsh_C PF12316.3 KFX96742.1 - 0.00025 21.2 1.1 0.00027 21.1 0.3 1.4 1 1 0 1 1 1 1 Segment polarity protein dishevelled (Dsh) C terminal AMP-binding PF00501.23 KFX96743.1 - 9.7e-66 221.8 0.0 1.5e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KFX96743.1 - 1e-32 113.2 0.0 1.6e-32 112.5 0.0 1.2 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 KFX96743.1 - 6.3e-08 32.7 0.0 1.9e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KFX96743.1 - 0.00031 21.6 0.1 0.00088 20.1 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAD_binding_3 PF01494.14 KFX96749.1 - 1.9e-17 63.4 1.1 1.6e-15 57.0 0.4 2.6 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KFX96749.1 - 0.039 13.9 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF4244 PF14029.1 KFX96751.1 - 7.3 5.7 6.8 0.51 9.4 1.2 1.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4244) Orn_Arg_deC_N PF02784.11 KFX96752.1 - 3.3e-63 213.2 0.0 4.1e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KFX96752.1 - 1.1e-14 54.1 0.0 1.8e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Myco_arth_vir_N PF09610.5 KFX96754.1 - 0.063 13.2 0.9 0.087 12.7 0.7 1.2 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) TTL PF03133.10 KFX96755.1 - 9.1e-40 136.4 0.0 1.3e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 KFX96755.1 - 8.3e-05 22.3 0.0 0.0025 17.5 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 KFX96755.1 - 0.014 14.2 0.0 0.026 13.3 0.0 1.4 1 0 0 1 1 1 0 YheC/D like ATP-grasp Mito_fiss_reg PF05308.6 KFX96756.1 - 0.064 12.6 9.1 0.08 12.2 6.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KFX96756.1 - 1.2 8.3 10.7 1.7 7.8 7.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal AAA_12 PF13087.1 KFX96758.1 - 1.1e-39 135.8 0.3 1.9e-39 135.1 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFX96758.1 - 1.1e-24 87.2 1.3 2.4e-24 86.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFX96758.1 - 2e-07 30.6 0.0 5.2e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 KFX96758.1 - 4e-07 29.3 2.2 0.00076 18.5 0.0 2.9 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) zf-CCCH PF00642.19 KFX96758.1 - 0.0016 18.0 1.4 0.0031 17.1 1.0 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA_30 PF13604.1 KFX96758.1 - 0.0018 17.8 0.1 0.0067 16.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KFX96758.1 - 0.018 14.4 0.1 0.042 13.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KFX96758.1 - 0.03 13.5 0.1 0.084 12.0 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AAA_16 PF13191.1 KFX96758.1 - 0.032 14.2 0.0 0.13 12.2 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.10 KFX96758.1 - 0.041 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KFX96758.1 - 0.071 13.2 0.2 0.67 10.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain UvrD_C_2 PF13538.1 KFX96758.1 - 0.082 13.0 0.0 0.19 11.8 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Mg_chelatase PF01078.16 KFX96758.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DcpS_C PF11969.3 KFX96777.1 - 0.02 15.1 0.0 0.025 14.8 0.0 1.2 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Cas_CXXC_CXXC PF09706.5 KFX96782.1 - 0.068 13.3 0.1 0.085 13.0 0.1 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_CXXC_CXXC) GFO_IDH_MocA PF01408.17 KFX96783.1 - 1.3e-18 67.6 0.0 2.1e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KFX96783.1 - 0.052 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain DUF3425 PF11905.3 KFX96784.1 - 2.9e-28 98.4 0.2 5e-28 97.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Med2 PF11214.3 KFX96787.1 - 0.0076 16.2 0.1 0.018 15.0 0.1 1.7 1 1 0 1 1 1 1 Mediator complex subunit 2 TPR_7 PF13176.1 KFX96787.1 - 0.015 15.0 0.1 0.29 11.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFX96787.1 - 0.064 13.9 0.9 9.7 7.1 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Prefoldin_2 PF01920.15 KFX96787.1 - 0.075 12.7 1.3 0.11 12.2 0.2 1.7 2 0 0 2 2 2 0 Prefoldin subunit THOC7 PF05615.8 KFX96787.1 - 0.12 12.6 3.9 1.2 9.4 0.2 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 WD40 PF00400.27 KFX96788.1 - 9.2e-38 126.7 2.1 5.9e-08 32.3 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.9 KFX96788.1 - 6.2e-30 103.0 17.5 1.1e-29 102.2 12.1 1.5 1 0 0 1 1 1 1 Sof1-like domain BBS2_Mid PF14783.1 KFX96788.1 - 7e-05 22.5 0.3 3.9 7.3 0.0 4.7 2 2 3 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.11 KFX96788.1 - 0.0018 16.6 0.4 0.014 13.7 0.1 2.5 3 1 0 3 3 3 1 Cytochrome D1 heme domain TauD PF02668.11 KFX96789.1 - 1.9e-45 155.5 0.0 2.4e-45 155.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DPPIV_N PF00930.16 KFX96790.1 - 1.8e-111 372.1 0.8 2.4e-111 371.7 0.6 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KFX96790.1 - 2e-55 187.3 2.5 4e-55 186.3 1.7 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFX96790.1 - 8.3e-10 38.5 0.2 1.7e-09 37.5 0.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KFX96790.1 - 2e-07 30.6 1.2 1.3e-05 24.7 0.2 2.5 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 KFX96790.1 - 9.9e-06 25.5 0.6 0.00018 21.4 0.4 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KFX96790.1 - 0.043 13.0 0.1 0.28 10.4 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family AXE1 PF05448.7 KFX96790.1 - 0.057 11.9 0.0 0.86 8.0 0.0 2.2 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydro_lipase PF04083.11 KFX96790.1 - 0.083 12.2 1.0 0.36 10.2 0.0 2.6 3 0 0 3 3 3 0 Partial alpha/beta-hydrolase lipase region PAF-AH_p_II PF03403.8 KFX96790.1 - 0.092 11.0 0.0 0.55 8.4 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II PP2C_2 PF13672.1 KFX96791.1 - 2.3e-10 40.2 0.3 3.7e-10 39.5 0.2 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KFX96791.1 - 1.8e-09 37.6 0.4 9.2e-09 35.2 0.3 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 KFX96791.1 - 3.8e-07 29.7 0.2 0.027 13.8 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C BUD22 PF09073.5 KFX96794.1 - 0.09 11.8 0.8 0.13 11.2 0.6 1.2 1 0 0 1 1 1 0 BUD22 Pribosyl_synth PF14572.1 KFX96795.1 - 4.7e-42 143.8 0.9 3e-36 124.8 0.2 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 KFX96795.1 - 3.8e-30 103.9 0.0 1.1e-29 102.5 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 KFX96795.1 - 9.8e-11 41.4 0.3 2.4e-10 40.1 0.2 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain RNA_pol_Rpb4 PF03874.11 KFX96796.1 - 1e-18 67.4 0.0 1.4e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Ras PF00071.17 KFX96797.1 - 3.8e-17 62.1 0.0 5.5e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX96797.1 - 6.5e-07 29.8 0.0 9.3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFX96797.1 - 0.0018 17.5 0.0 0.031 13.5 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family NACHT PF05729.7 KFX96797.1 - 0.0025 17.4 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 KFX96797.1 - 0.023 14.8 0.0 0.047 13.8 0.0 1.6 1 1 0 1 1 1 0 RNA helicase AAA_16 PF13191.1 KFX96797.1 - 0.062 13.2 0.0 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.15 KFX96797.1 - 0.1 11.2 0.0 0.18 10.4 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit MMR_HSR1 PF01926.18 KFX96797.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 KFX96797.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 KFX96797.1 - 0.14 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PseudoU_synth_1 PF01416.15 KFX96798.1 - 2.2e-29 101.9 0.0 4.4e-23 81.7 0.0 3.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase zf-H2C2_2 PF13465.1 KFX96821.1 - 6.9e-23 79.7 23.3 3.2e-07 30.3 0.7 5.6 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 KFX96821.1 - 3.5e-21 74.2 25.3 5.2e-05 23.3 1.9 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX96821.1 - 9.6e-16 56.8 24.9 0.00018 21.5 0.2 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFX96821.1 - 7.1e-06 26.0 8.4 0.54 10.4 0.0 4.7 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFX96821.1 - 1.3e-05 25.2 10.3 0.059 13.6 0.0 4.2 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KFX96821.1 - 0.0013 18.5 16.9 0.15 12.0 0.5 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger C1_4 PF07975.7 KFX96821.1 - 0.067 13.2 0.5 4.3 7.4 0.0 2.6 2 1 1 3 3 3 0 TFIIH C1-like domain zf-C2HC_2 PF13913.1 KFX96821.1 - 0.075 12.7 9.1 2.5 7.8 0.8 3.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type XPA_N PF01286.13 KFX96821.1 - 0.14 11.8 0.3 0.14 11.8 0.2 3.4 4 0 0 4 4 4 0 XPA protein N-terminal zf-Di19 PF05605.7 KFX96821.1 - 0.32 11.1 8.9 5.8 7.1 0.1 3.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding C1_1 PF00130.17 KFX96821.1 - 3.6 7.3 7.1 1.4 8.6 0.9 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FBPase PF00316.15 KFX96822.1 - 5.7e-124 413.1 0.0 6.5e-124 412.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Usp PF00582.21 KFX96824.1 - 2.8e-22 79.4 1.1 1.8e-15 57.3 0.0 2.5 2 0 0 2 2 2 2 Universal stress protein family Metal_resist PF13801.1 KFX96824.1 - 0.31 11.0 7.4 0.096 12.6 0.4 3.3 4 0 0 4 4 4 0 Heavy-metal resistance Pkinase PF00069.20 KFX96826.1 - 8e-55 185.7 0.0 1.3e-54 185.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX96826.1 - 3.1e-30 105.1 0.0 4.5e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFX96826.1 - 0.0013 18.5 0.0 0.0039 16.9 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KFX96826.1 - 0.0038 16.3 0.0 0.0063 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFX96826.1 - 0.031 13.2 0.0 0.11 11.4 0.0 1.8 2 0 0 2 2 2 0 Kinase-like GFO_IDH_MocA PF01408.17 KFX96827.1 - 4.8e-17 62.5 0.4 2.2e-16 60.4 0.3 2.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold HOOK PF05622.7 KFX96827.1 - 3.2e-12 45.1 69.8 2.2e-07 29.1 42.8 3.5 3 1 0 3 3 3 3 HOOK protein CH PF00307.26 KFX96827.1 - 0.0045 17.0 0.4 0.2 11.7 0.0 3.2 3 0 0 3 3 3 1 Calponin homology (CH) domain NYD-SP28_assoc PF14775.1 KFX96827.1 - 0.014 15.0 1.6 0.014 15.0 1.1 5.8 6 1 1 7 7 7 0 Sperm tail C-terminal domain DUF904 PF06005.7 KFX96827.1 - 0.014 15.6 0.4 0.014 15.6 0.3 8.8 5 1 1 6 6 6 0 Protein of unknown function (DUF904) HALZ PF02183.13 KFX96827.1 - 0.018 14.7 1.4 0.018 14.7 1.0 9.4 8 4 3 11 11 11 0 Homeobox associated leucine zipper Peptidase_M4 PF01447.13 KFX96827.1 - 4.1 7.5 6.5 0.62 10.1 0.6 2.6 2 1 0 2 2 2 0 Thermolysin metallopeptidase, catalytic domain RXT2_N PF08595.6 KFX96835.1 - 0.038 13.8 2.7 0.043 13.6 1.9 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 KFX96835.1 - 0.091 12.2 3.3 0.12 11.9 2.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin Orbi_VP6 PF01516.11 KFX96835.1 - 0.25 10.3 4.4 0.27 10.2 3.0 1.0 1 0 0 1 1 1 0 Orbivirus helicase VP6 Sporozoite_P67 PF05642.6 KFX96835.1 - 0.29 8.9 3.9 0.28 9.0 2.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF2457 PF10446.4 KFX96835.1 - 2.3 6.8 10.1 2.3 6.8 7.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MFS_1 PF07690.11 KFX96837.1 - 7.9e-33 113.6 28.8 7.9e-33 113.6 20.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3671 PF12420.3 KFX96837.1 - 0.13 12.2 4.5 2.1 8.3 0.0 4.0 3 2 1 4 4 4 0 Protein of unknown function Kinesin PF00225.18 KFX96839.1 - 1.1e-93 313.5 0.0 1.9e-93 312.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain IncA PF04156.9 KFX96839.1 - 0.34 10.4 3.9 1.2 8.6 2.8 1.8 2 0 0 2 2 2 0 IncA protein BBP1_C PF15272.1 KFX96839.1 - 0.4 10.1 5.4 1.2 8.6 2.3 2.3 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal RCC1 PF00415.13 KFX96840.1 - 1.5e-53 178.7 3.3 1.8e-09 37.6 0.0 7.7 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFX96840.1 - 7e-34 114.7 28.2 7.8e-10 38.1 0.3 6.7 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat PG_binding_3 PF09374.5 KFX96840.1 - 0.013 15.4 0.5 0.53 10.3 0.0 2.5 2 0 0 2 2 2 0 Predicted Peptidoglycan domain CBM_X PF06204.6 KFX96840.1 - 0.19 11.2 3.5 12 5.4 0.0 3.3 3 0 0 3 3 3 0 Putative carbohydrate binding domain DUF1811 PF08838.5 KFX96840.1 - 0.21 11.5 0.0 3.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1811) MFS_1 PF07690.11 KFX96841.1 - 8.7e-26 90.4 50.4 4.3e-15 55.2 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RseC_MucC PF04246.7 KFX96841.1 - 0.48 10.0 0.0 0.48 10.0 0.0 2.9 3 1 2 5 5 5 0 Positive regulator of sigma(E), RseC/MucC Shisa PF13908.1 KFX96842.1 - 0.0014 18.8 2.8 0.0015 18.7 2.0 1.0 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF3824 PF12868.2 KFX96842.1 - 0.0087 16.9 2.6 0.012 16.5 1.8 1.2 1 0 0 1 1 1 1 Domain of unknwon function (DUF3824) Pro-rich PF15240.1 KFX96842.1 - 0.51 10.4 22.8 0.58 10.2 15.8 1.1 1 0 0 1 1 1 0 Proline-rich APC_CDC26 PF10471.4 KFX96842.1 - 2.6 8.8 9.7 3.5 8.4 6.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 PAT1 PF09770.4 KFX96842.1 - 6.7 4.8 16.6 6.8 4.7 11.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ApbA PF02558.11 KFX96843.1 - 1.2e-23 83.2 0.0 1.8e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KFX96843.1 - 5.1e-23 81.4 0.1 1.1e-22 80.2 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal COQ9 PF08511.6 KFX96855.1 - 9e-24 82.7 0.0 1.8e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 COQ9 Amidase PF01425.16 KFX96856.1 - 3.8e-95 319.3 0.0 4.7e-95 319.0 0.0 1.1 1 0 0 1 1 1 1 Amidase 2OG-FeII_Oxy_2 PF13532.1 KFX96857.1 - 7.8e-34 117.2 0.0 9.2e-33 113.7 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 KFX96858.1 - 6e-72 241.9 0.0 7.9e-72 241.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX96858.1 - 1.9e-31 109.0 0.0 2.5e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX96858.1 - 0.002 17.1 0.0 0.0031 16.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFX96858.1 - 0.0071 16.1 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KFX96858.1 - 0.019 13.8 0.1 0.029 13.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF2796 PF10986.3 KFX96859.1 - 0.014 15.3 1.1 0.021 14.7 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) SPX PF03105.14 KFX96859.1 - 0.016 14.9 3.1 0.022 14.5 2.2 1.1 1 0 0 1 1 1 0 SPX domain WD40 PF00400.27 KFX96869.1 - 1e-07 31.5 14.6 0.0043 16.8 0.0 6.6 6 0 0 6 6 6 3 WD domain, G-beta repeat SCAN PF02023.12 KFX96869.1 - 0.064 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 SCAN domain Glyco_hydro_43 PF04616.9 KFX96870.1 - 1e-38 133.0 4.4 1.4e-38 132.6 3.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_10 PF00331.15 KFX96871.1 - 3.1e-101 338.5 0.0 3.6e-101 338.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.10 KFX96871.1 - 0.0078 15.3 0.1 0.057 12.5 0.0 1.9 1 1 1 2 2 2 1 Beta-galactosidase Glyco_hydro_43 PF04616.9 KFX96872.1 - 3.6e-52 177.2 8.7 6.7e-52 176.3 3.7 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 CBM_6 PF03422.10 KFX96872.1 - 1.6e-37 128.4 5.4 3.7e-37 127.2 3.8 1.6 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) Glyco_hydro_32N PF00251.15 KFX96872.1 - 2.5e-05 23.7 2.1 3.9e-05 23.1 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_62 PF03664.8 KFX96873.1 - 8.1e-151 500.6 13.3 9.3e-151 500.4 9.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Melibiase PF02065.13 KFX96874.1 - 3.5e-18 65.4 3.8 2.9e-16 59.1 0.1 2.3 1 1 0 2 2 2 2 Melibiase DUF3425 PF11905.3 KFX96875.1 - 8.7e-17 61.2 0.7 1.8e-16 60.2 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Metal_resist PF13801.1 KFX96875.1 - 0.063 13.2 0.1 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Heavy-metal resistance Pyr_redox_3 PF13738.1 KFX96876.1 - 7.9e-18 65.2 0.0 1.6e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFX96876.1 - 1.9e-08 32.9 0.0 1.9e-06 26.3 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KFX96876.1 - 5.1e-07 29.6 0.0 4.1e-06 26.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 KFX96876.1 - 7.8e-05 22.7 0.0 0.0014 18.7 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 KFX96876.1 - 0.0009 19.0 0.1 0.3 10.8 0.1 3.5 2 1 1 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 KFX96876.1 - 0.001 18.0 0.1 0.84 8.4 0.1 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFX96876.1 - 0.0026 17.6 0.0 0.023 14.6 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFX96876.1 - 0.0079 15.2 0.2 0.48 9.4 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KFX96876.1 - 0.018 13.9 0.0 5.3 5.8 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 KFX96876.1 - 0.026 13.3 0.0 0.046 12.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_7 PF13241.1 KFX96876.1 - 0.096 12.9 0.2 0.47 10.7 0.0 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 KFX96876.1 - 0.1 11.7 0.0 0.25 10.4 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Beta-lactamase PF00144.19 KFX96877.1 - 6.2e-64 216.0 0.0 7e-64 215.9 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase PBP PF01161.15 KFX96878.1 - 1.5e-12 47.5 0.0 1.9e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Fimbrial_PilY2 PF14481.1 KFX96879.1 - 0.1 11.9 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 Citrate_synt PF00285.16 KFX96880.1 - 5.7e-102 341.0 0.0 8.8e-102 340.4 0.0 1.3 1 0 0 1 1 1 1 Citrate synthase RRM_1 PF00076.17 KFX96881.1 - 1.2e-08 34.5 0.0 2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX96881.1 - 2.5e-08 33.6 0.0 4.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX96881.1 - 8.4e-06 25.6 0.1 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 KFX96881.1 - 0.0024 18.0 0.0 0.0073 16.5 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase II-binding domain. Acyl-CoA_dh_1 PF00441.19 KFX96884.1 - 1.6e-41 141.9 3.5 2.5e-41 141.2 2.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFX96884.1 - 6.3e-28 97.6 0.5 1.4e-27 96.4 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KFX96884.1 - 3.2e-17 61.7 0.1 5.8e-17 60.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFX96884.1 - 5.1e-17 62.3 0.7 7.7e-17 61.8 0.5 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KFX96884.1 - 0.084 12.2 0.1 0.31 10.3 0.1 1.9 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Pkinase PF00069.20 KFX96885.1 - 9.1e-64 215.0 0.0 1.6e-63 214.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX96885.1 - 7.3e-37 126.8 0.0 1.3e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 KFX96885.1 - 2.2e-27 94.5 19.0 9.1e-15 54.1 2.9 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 KFX96885.1 - 2.6e-19 68.6 29.0 2.9e-11 42.9 6.6 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 KFX96885.1 - 1e-13 51.5 3.8 2.9e-13 50.0 2.6 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFX96885.1 - 0.0067 15.4 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like FYVE_2 PF02318.11 KFX96885.1 - 0.53 10.1 18.2 3.4 7.6 2.9 2.7 1 1 1 2 2 2 0 FYVE-type zinc finger She9_MDM33 PF05546.6 KFX96887.1 - 8.1e-85 283.5 1.7 1.1e-84 283.1 1.2 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.15 KFX96887.1 - 0.012 15.1 0.9 0.021 14.3 0.6 1.3 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Tox-SHH PF15652.1 KFX96887.1 - 0.8 10.3 4.1 14 6.3 0.1 2.7 3 0 0 3 3 3 0 HNH/Endo VII superfamily toxin with a SHH signature PspA_IM30 PF04012.7 KFX96887.1 - 5.7 6.2 13.7 0.17 11.2 4.1 2.1 2 0 0 2 2 2 0 PspA/IM30 family AA_permease PF00324.16 KFX96895.1 - 1.7e-135 452.1 49.3 2.1e-135 451.7 34.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFX96895.1 - 2.5e-34 118.5 54.4 3.1e-34 118.2 37.7 1.1 1 0 0 1 1 1 1 Amino acid permease PALP PF00291.20 KFX96898.1 - 8.3e-09 35.0 0.0 9.5e-09 34.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ribosomal_L7Ae PF01248.21 KFX96903.1 - 8.3e-21 73.3 1.0 1.9e-20 72.1 0.7 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family NPR2 PF06218.6 KFX96915.1 - 7e-122 407.1 0.5 5.3e-108 361.4 0.1 2.0 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.8 KFX96915.1 - 0.01 14.4 0.0 0.026 13.0 0.0 1.6 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 Methyltransf_16 PF10294.4 KFX96916.1 - 1.2e-17 63.9 0.0 1.7e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KFX96916.1 - 6.9e-06 26.6 0.0 1.2e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX96916.1 - 0.00051 20.0 0.1 0.00094 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFX96916.1 - 0.0022 17.1 0.0 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KFX96916.1 - 0.003 16.9 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KFX96916.1 - 0.0052 16.5 0.0 0.0093 15.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain WD40 PF00400.27 KFX96919.1 - 5.2e-42 140.2 1.5 3.1e-08 33.2 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 KFX96919.1 - 2.2e-05 24.0 0.2 4.6e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX96919.1 - 0.00021 20.8 0.1 0.00053 19.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KFX96919.1 - 0.00042 18.5 0.2 0.048 11.7 0.0 3.0 2 1 1 3 3 3 1 Nucleoporin Nup120/160 DUF605 PF04652.11 KFX96919.1 - 0.0028 17.0 11.1 0.0028 17.0 7.7 2.2 2 0 0 2 2 2 1 Vta1 like Syndecan PF01034.15 KFX96920.1 - 0.22 11.1 0.0 0.44 10.2 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Lamp PF01299.12 KFX96920.1 - 1.5 7.9 0.0 1.5 7.9 0.0 4.1 2 1 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) Peptidase_C12 PF01088.16 KFX96929.1 - 1.1e-67 227.3 0.0 1.5e-67 226.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Zn_clus PF00172.13 KFX96930.1 - 1.1e-09 38.0 10.2 1.7e-09 37.4 7.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFX96930.1 - 8.7e-06 24.5 0.1 1.3e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 KFX96936.1 - 1.1e-88 297.8 28.3 1.5e-60 205.0 4.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFX96936.1 - 1.9e-25 89.3 29.1 3.5e-22 78.5 7.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFX96936.1 - 0.00015 20.0 1.7 0.00027 19.2 1.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Mem_trans PF03547.13 KFX96936.1 - 0.0025 16.1 0.5 0.0061 14.8 0.3 1.6 1 0 0 1 1 1 1 Membrane transport protein Imp-YgjV PF10688.4 KFX96939.1 - 0.025 13.9 1.4 0.031 13.6 1.0 1.0 1 0 0 1 1 1 0 Bacterial inner membrane protein PAT1 PF09770.4 KFX96939.1 - 0.081 11.1 0.1 0.099 10.8 0.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PUF PF00806.14 KFX96944.1 - 3.3e-28 95.5 7.6 1.5e-08 33.6 0.1 4.8 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat Repressor_Mnt PF11423.3 KFX96944.1 - 0.044 13.1 0.4 0.11 11.8 0.3 1.5 1 0 0 1 1 1 0 Regulatory protein Mnt MFS_1 PF07690.11 KFX96947.1 - 8.5e-31 106.9 29.7 4.3e-30 104.6 21.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.1 KFX96947.1 - 0.1 12.6 0.1 0.1 12.6 0.1 3.5 4 1 0 4 4 4 0 Protein of unknown function (DUF4231) Aminotran_3 PF00202.16 KFX96948.1 - 8.6e-106 353.6 0.0 1.1e-105 353.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 KFX96948.1 - 1.9e-05 23.9 0.0 3.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KFX96948.1 - 0.00024 20.1 0.0 0.00033 19.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II AAA_22 PF13401.1 KFX96948.1 - 0.033 14.3 0.0 1.9 8.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain Glyco_transf_22 PF03901.12 KFX96949.1 - 5.6e-81 272.6 19.5 6.7e-81 272.4 13.5 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family CAF-1_p150 PF11600.3 KFX96950.1 - 0.0069 15.7 22.2 0.01 15.2 15.4 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Erf4 PF10256.4 KFX96950.1 - 0.076 12.8 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family NARP1 PF12569.3 KFX96950.1 - 1.1 7.8 12.6 1.6 7.4 8.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RR_TM4-6 PF06459.7 KFX96950.1 - 2.5 7.9 11.2 4.1 7.2 7.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDRGK PF09756.4 KFX96950.1 - 4 6.7 22.5 8.1 5.8 15.6 1.5 1 0 0 1 1 1 0 DDRGK domain Transp_cyt_pur PF02133.10 KFX96952.1 - 5.1e-147 489.9 34.7 6.1e-147 489.7 24.1 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3405 PF11885.3 KFX96953.1 - 2.2e-130 435.2 0.0 2.9e-130 434.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) tRNA-synt_1d PF00750.14 KFX96958.1 - 1.6e-83 280.4 9.4 4.7e-83 278.9 6.5 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 KFX96958.1 - 1.5e-30 105.6 0.1 4.5e-30 104.0 0.1 1.9 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 KFX96958.1 - 6.7e-07 29.7 0.0 1.9e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain Hemerythrin PF01814.18 KFX96959.1 - 7.8e-07 29.3 0.0 9.8e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Glyco_hydro_61 PF03443.9 KFX96960.1 - 4.5e-51 173.7 0.0 5.5e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 F5_F8_type_C PF00754.20 KFX96961.1 - 2.3e-10 40.3 0.0 7.1e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 F5/8 type C domain Glyco_hydro_42 PF02449.10 KFX96961.1 - 0.012 14.7 0.0 0.47 9.5 0.0 2.1 1 1 1 2 2 2 0 Beta-galactosidase Sugar_tr PF00083.19 KFX96962.1 - 6.2e-79 265.6 24.5 7e-79 265.5 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX96962.1 - 5.8e-40 137.0 49.3 2e-34 118.8 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFX96962.1 - 0.03 12.5 11.4 0.0049 15.1 3.1 2.5 2 1 1 3 3 3 0 Fungal trichothecene efflux pump (TRI12) DUF202 PF02656.10 KFX96962.1 - 2.2 8.5 9.3 2.1 8.6 0.4 3.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Alpha-amylase PF00128.19 KFX96963.1 - 3.6e-98 328.8 0.2 3.6e-98 328.8 0.1 1.9 2 1 1 3 3 3 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KFX96963.1 - 0.0013 17.6 0.0 0.0022 16.9 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Alpha-amylase_C PF02806.13 KFX96963.1 - 0.0046 17.0 0.1 0.042 13.9 0.2 2.5 2 1 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain DUF4202 PF13875.1 KFX96964.1 - 9.3e-78 260.1 0.7 1.1e-77 259.9 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) DUF3505 PF12013.3 KFX96964.1 - 0.11 12.7 0.2 0.2 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) Glyco_hydro_31 PF01055.21 KFX96965.1 - 1.6e-132 442.4 1.8 2e-132 442.1 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KFX96965.1 - 0.00033 20.4 1.1 0.0026 17.5 0.1 2.8 3 1 0 3 3 3 1 Galactose mutarotase-like Peptidase_M20 PF01546.23 KFX96966.1 - 1e-20 74.0 0.0 1.6e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFX96966.1 - 1.2e-14 54.0 0.0 3.2e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Ldh_1_N PF00056.18 KFX96967.1 - 1.1e-44 151.6 0.1 3.6e-44 150.0 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KFX96967.1 - 7.5e-41 139.7 0.2 1.2e-40 139.1 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KFX96967.1 - 0.024 13.3 0.0 0.035 12.7 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Sugar_tr PF00083.19 KFX96968.1 - 3.1e-34 118.3 25.2 8.5e-34 116.8 17.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX96968.1 - 1.3e-29 103.0 29.1 5e-23 81.3 9.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PLDc PF00614.17 KFX96970.1 - 5.4e-15 54.6 2.5 2.4e-07 30.3 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KFX96970.1 - 3.3e-12 46.2 0.0 2e-05 24.3 0.0 3.4 3 0 0 3 3 3 3 PLD-like domain GLTP PF08718.6 KFX96971.1 - 3.7e-46 156.8 0.0 4.6e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Macro PF01661.16 KFX96972.1 - 2.5e-39 133.8 0.3 4.7e-39 132.9 0.2 1.5 1 0 0 1 1 1 1 Macro domain tRNA-synt_1c PF00749.16 KFX96973.1 - 9.5e-95 316.8 0.0 1.2e-94 316.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KFX96973.1 - 4.8e-29 101.2 0.0 1.7e-28 99.4 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Ribosomal_60s PF00428.14 KFX96973.1 - 5 7.5 14.4 12 6.4 10.0 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein BMF PF15185.1 KFX96975.1 - 0.0048 16.2 3.4 0.011 15.0 2.4 1.6 1 0 0 1 1 1 1 Bcl-2-modifying factor, apoptosis Ribosomal_60s PF00428.14 KFX96975.1 - 0.0067 16.7 10.9 0.024 15.0 7.5 1.9 1 0 0 1 1 1 1 60s Acidic ribosomal protein BSP_II PF05432.6 KFX96975.1 - 0.0097 15.2 9.1 0.018 14.3 6.3 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Nop14 PF04147.7 KFX96975.1 - 0.011 13.7 0.9 0.016 13.1 0.6 1.3 1 0 0 1 1 1 0 Nop14-like family Usp PF00582.21 KFX96975.1 - 4.8 7.3 6.9 18 5.5 1.5 2.4 2 0 0 2 2 2 0 Universal stress protein family Hydrophobin_2 PF06766.6 KFX96976.1 - 0.0023 17.5 6.6 0.0053 16.4 4.6 1.7 1 1 0 1 1 1 1 Fungal hydrophobin uDENN PF03456.13 KFX96976.1 - 0.032 14.1 0.5 0.048 13.6 0.4 1.2 1 0 0 1 1 1 0 uDENN domain Hydrophobin_2 PF06766.6 KFX96977.1 - 1.1e-06 28.2 7.0 1.6e-06 27.6 4.8 1.4 1 0 0 1 1 1 1 Fungal hydrophobin Methyltransf_2 PF00891.13 KFX96978.1 - 2.5e-34 118.5 0.0 4.3e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KFX96978.1 - 0.00015 22.3 0.0 0.00034 21.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX96978.1 - 0.024 14.2 0.0 0.072 12.6 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain CheR PF01739.13 KFX96978.1 - 0.068 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain PIP5K PF01504.13 KFX96981.1 - 3.7e-60 203.1 0.0 7.7e-60 202.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Metallophos PF00149.23 KFX96982.1 - 1.1e-39 135.9 0.1 1.4e-39 135.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SUR7 PF06687.7 KFX96983.1 - 8e-26 90.9 11.2 1e-25 90.5 7.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family Pam17 PF08566.5 KFX96983.1 - 0.11 12.1 0.2 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 SET PF00856.23 KFX96984.1 - 7.2e-19 68.6 1.6 5.4e-18 65.8 0.1 3.1 3 2 0 3 3 3 1 SET domain ApoLp-III PF07464.6 KFX96984.1 - 0.014 15.4 0.1 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) RPEL PF02755.10 KFX96985.1 - 1.2e-23 81.6 18.0 1e-09 37.3 2.0 3.9 4 0 0 4 4 4 3 RPEL repeat MCPVI PF02993.9 KFX96985.1 - 0.041 14.0 3.2 0.035 14.2 1.3 1.5 1 1 0 1 1 1 0 Minor capsid protein VI CP12 PF02672.10 KFX96985.1 - 0.069 13.6 0.4 18 5.8 0.1 2.5 2 0 0 2 2 2 0 CP12 domain IMS PF00817.15 KFX96986.1 - 6.9e-41 139.5 0.1 1.7e-40 138.2 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 KFX96986.1 - 4e-10 39.7 0.0 8.5e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KFX96986.1 - 0.0026 17.7 0.0 0.0076 16.2 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif FKBP_C PF00254.23 KFX96987.1 - 5.4e-34 116.0 0.0 8.8e-34 115.4 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Inhibitor_I53 PF11714.3 KFX96987.1 - 0.087 12.8 0.6 0.68 9.9 0.0 2.1 2 0 0 2 2 2 0 Thrombin inhibitor Madanin Ric8 PF10165.4 KFX96990.1 - 4.4e-60 203.7 0.1 5e-60 203.5 0.1 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn CLTH PF10607.4 KFX96992.1 - 3.9e-28 97.9 0.0 5.5e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 KFX96992.1 - 4.6e-26 91.3 0.2 7.7e-26 90.6 0.1 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 KFX96992.1 - 0.00021 20.9 0.0 0.00021 20.9 0.0 2.3 3 0 0 3 3 3 1 LisH NACHT PF05729.7 KFX96995.1 - 2.4e-07 30.5 0.1 6.5e-07 29.1 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KFX96995.1 - 3.8e-05 23.8 0.6 0.0002 21.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain CENP-T PF15511.1 KFX96995.1 - 0.036 13.3 0.7 0.35 10.0 0.0 2.0 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T HMG_box PF00505.14 KFX97002.1 - 3.5e-12 46.3 0.1 9e-12 45.0 0.1 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFX97002.1 - 0.053 13.8 0.1 0.12 12.7 0.1 1.7 1 0 0 1 1 1 0 HMG-box domain Lactamase_B PF00753.22 KFX97006.1 - 0.002 17.8 0.1 0.0033 17.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Prok-RING_1 PF14446.1 KFX97006.1 - 0.17 11.6 0.2 0.34 10.6 0.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Amidase PF01425.16 KFX97007.1 - 3.1e-85 286.6 0.0 3.8e-85 286.3 0.0 1.1 1 0 0 1 1 1 1 Amidase CASP_C PF08172.7 KFX97048.1 - 4.9e-86 287.7 0.9 4.9e-86 287.7 0.7 3.7 2 1 1 3 3 3 1 CASP C terminal Laminin_I PF06008.9 KFX97048.1 - 0.0062 15.8 10.9 0.0062 15.8 7.5 3.6 3 2 0 3 3 3 1 Laminin Domain I UPF0184 PF03670.8 KFX97048.1 - 0.045 13.9 8.6 0.73 10.0 0.4 3.5 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) DUF904 PF06005.7 KFX97048.1 - 0.05 13.9 0.3 0.05 13.9 0.2 6.7 3 2 1 4 4 4 0 Protein of unknown function (DUF904) Mit_KHE1 PF10173.4 KFX97048.1 - 1.7 8.4 4.8 4.3 7.1 3.3 1.7 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related ATG16 PF08614.6 KFX97048.1 - 9.7 5.9 54.4 12 5.7 0.1 5.8 3 1 2 5 5 5 0 Autophagy protein 16 (ATG16) VCBS PF13517.1 KFX97049.1 - 7.1e-35 119.1 61.1 3.8e-09 36.7 1.7 8.9 4 2 6 11 11 11 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KFX97049.1 - 5.2e-14 51.4 41.0 3.3e-05 23.4 0.3 7.6 7 0 0 7 7 7 4 FG-GAP repeat Lipase_GDSL PF00657.17 KFX97049.1 - 3.7e-11 43.2 0.2 1.3e-10 41.5 0.1 1.9 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.3 KFX97049.1 - 1.8e-09 37.2 9.8 0.17 11.3 0.0 6.0 4 2 2 6 6 6 4 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_2 PF13472.1 KFX97049.1 - 3.2e-07 30.6 0.1 7.1e-07 29.5 0.1 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family G-alpha PF00503.15 KFX97050.1 - 1.4e-119 399.2 0.6 1.7e-119 398.9 0.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KFX97050.1 - 5.7e-14 51.7 1.0 3.2e-09 36.2 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFX97050.1 - 0.00028 20.0 2.3 0.021 13.9 0.1 2.8 2 2 0 2 2 2 2 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 KFX97050.1 - 0.0091 15.4 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_29 PF13555.1 KFX97050.1 - 0.042 13.3 0.0 0.094 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SUR7 PF06687.7 KFX97051.1 - 4.2e-18 65.7 9.4 5.8e-18 65.2 1.6 2.0 1 1 1 2 2 2 1 SUR7/PalI family Claudin_2 PF13903.1 KFX97051.1 - 2.6e-05 23.9 2.8 2.6e-05 23.9 2.0 2.1 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF805 PF05656.9 KFX97051.1 - 0.00072 19.3 0.5 0.00072 19.3 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF805) RCR PF12273.3 KFX97051.1 - 0.04 14.4 0.1 0.04 14.4 0.1 2.2 3 0 0 3 3 2 0 Chitin synthesis regulation, resistance to Congo red COX2_TM PF02790.10 KFX97051.1 - 0.049 13.5 2.6 0.1 12.5 0.1 2.2 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain DUF161 PF02588.10 KFX97051.1 - 0.091 13.0 0.3 0.091 13.0 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized BCR, YitT family COG1284 DUF2663 PF10864.3 KFX97051.1 - 0.19 11.9 1.5 0.34 11.1 0.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2663) Phage_holin_4 PF05105.7 KFX97051.1 - 0.93 9.1 7.1 0.69 9.5 1.6 2.2 2 0 0 2 2 2 0 Holin family 7tm_1 PF00001.16 KFX97051.1 - 0.98 8.4 4.9 0.1 11.7 0.2 1.6 2 1 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) NicO PF03824.11 KFX97051.1 - 1.6 7.9 9.2 0.14 11.4 3.2 1.5 2 0 0 2 2 2 0 High-affinity nickel-transport protein FtsX PF02687.16 KFX97051.1 - 2.6 7.8 11.7 0.19 11.4 2.3 2.3 2 0 0 2 2 2 0 FtsX-like permease family MRAP PF15183.1 KFX97051.1 - 3.2 7.3 7.8 0.62 9.6 0.1 2.8 2 1 1 3 3 3 0 Melanocortin-2 receptor accessory protein family DctM PF06808.7 KFX97051.1 - 5.3 5.4 10.8 0.37 9.3 1.6 2.0 2 0 0 2 2 2 0 DctM-like transporters SIT PF15330.1 KFX97051.1 - 5.7 7.1 0.0 5.7 7.1 0.0 3.0 4 0 0 4 4 3 0 SHP2-interacting transmembrane adaptor protein, SIT DUF1282 PF06930.7 KFX97051.1 - 9.6 5.8 9.2 0.35 10.4 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) HhH-GPD PF00730.20 KFX97052.1 - 3.3e-10 40.1 0.0 1.4e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KFX97052.1 - 6.8e-08 31.7 0.0 6.8e-08 31.7 0.0 2.2 3 0 0 3 3 3 1 Helix-hairpin-helix motif HHH_8 PF14716.1 KFX97052.1 - 0.01 16.0 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain Lectin_leg-like PF03388.8 KFX97065.1 - 8e-07 28.4 0.0 9.7e-07 28.1 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Alg6_Alg8 PF03155.10 KFX97066.1 - 2.3e-143 478.4 28.1 1.2e-142 476.0 19.5 1.8 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Pkinase PF00069.20 KFX97073.1 - 1e-11 44.5 0.0 1.5e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX97073.1 - 8e-06 25.0 0.0 1.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4349 PF14257.1 KFX97076.1 - 1.3 8.2 6.8 1.5 7.9 4.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) CDC45 PF02724.9 KFX97076.1 - 1.3 6.9 3.8 1.4 6.8 2.7 1.0 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 KFX97076.1 - 3.7 7.0 9.4 5.4 6.5 6.5 1.3 1 1 0 1 1 1 0 YL1 nuclear protein DUF3016 PF11454.3 KFX97079.1 - 0.068 12.7 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) HEAT_2 PF13646.1 KFX97098.1 - 1.5e-11 44.4 9.9 0.014 15.6 0.0 7.6 7 2 3 10 10 10 4 HEAT repeats HEAT PF02985.17 KFX97098.1 - 9.1e-07 28.4 28.4 0.21 11.7 0.0 11.8 13 0 0 13 13 13 2 HEAT repeat CLASP_N PF12348.3 KFX97098.1 - 0.00085 18.7 2.8 0.59 9.4 0.0 4.0 4 0 0 4 4 4 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 KFX97098.1 - 0.0069 16.7 0.0 1 9.7 0.0 4.3 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region DUF1546 PF07571.8 KFX97098.1 - 0.011 15.8 0.6 3 8.0 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF1546) HEAT_EZ PF13513.1 KFX97098.1 - 0.07 13.6 12.8 28 5.3 0.0 7.9 7 1 1 8 8 8 0 HEAT-like repeat NifW PF03206.9 KFX97098.1 - 0.14 12.2 0.0 0.52 10.4 0.0 1.9 1 0 0 1 1 1 0 Nitrogen fixation protein NifW DUF2897 PF11446.3 KFX97099.1 - 0.039 13.7 0.0 0.076 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) PAP_PilO PF06864.7 KFX97099.1 - 0.04 12.2 0.1 0.056 11.7 0.0 1.1 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Chordopox_A33R PF05966.7 KFX97099.1 - 0.079 11.7 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Shisa PF13908.1 KFX97099.1 - 0.087 12.9 1.7 0.13 12.4 0.9 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator OAD_gamma PF04277.8 KFX97099.1 - 0.28 11.5 1.8 0.7 10.3 0.3 2.3 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain GFA PF04828.9 KFX97100.1 - 1.8e-14 53.4 0.2 4.7e-06 26.4 0.1 2.6 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Methyltransf_23 PF13489.1 KFX97100.1 - 1.8e-06 27.7 0.0 3.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX97100.1 - 1.8e-06 28.3 0.0 3.7e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX97100.1 - 4.1e-05 24.1 0.0 0.00012 22.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX97100.1 - 0.00011 22.5 0.0 0.00031 21.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX97100.1 - 0.00011 21.7 0.0 0.00034 20.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX97100.1 - 0.0003 20.8 0.0 0.00061 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX97100.1 - 0.0015 18.8 0.0 0.0033 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX97100.1 - 0.0088 15.4 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain DZR PF12773.2 KFX97100.1 - 0.039 13.7 3.3 12 5.7 1.8 3.0 2 1 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 KFX97100.1 - 0.052 12.7 9.5 0.44 9.8 0.0 3.9 4 0 0 4 4 4 0 zinc-ribbon domain DUF1106 PF06523.6 KFX97100.1 - 0.071 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1106) Plant_zn_clust PF10533.4 KFX97100.1 - 0.076 12.6 1.0 1.9 8.2 0.0 2.6 2 0 0 2 2 2 0 Plant zinc cluster domain zf-NADH-PPase PF09297.6 KFX97100.1 - 1.7 8.2 11.3 0.61 9.6 0.1 3.1 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain MFS_1 PF07690.11 KFX97101.1 - 2.5e-35 121.8 39.0 1.6e-27 96.1 17.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFX97101.1 - 0.00052 19.7 2.9 0.0024 17.6 2.0 2.2 1 1 0 1 1 1 1 MFS_1 like family adh_short PF00106.20 KFX97102.1 - 2.3e-14 53.6 0.0 3.3e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX97102.1 - 2.7e-08 33.8 0.0 3.4e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX97102.1 - 2.7e-07 30.4 0.0 3.9e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFX97102.1 - 7.6e-05 22.2 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX97102.1 - 0.028 14.4 0.0 0.12 12.3 0.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding Fungal_trans PF04082.13 KFX97103.1 - 0.002 17.0 0.1 0.0031 16.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TENA_THI-4 PF03070.11 KFX97104.1 - 3.8e-08 33.3 0.0 0.0011 18.7 0.0 2.4 2 0 0 2 2 2 2 TENA/THI-4/PQQC family MARVEL PF01284.18 KFX97105.1 - 1.9e-23 82.8 19.3 2.4e-23 82.5 13.4 1.0 1 0 0 1 1 1 1 Membrane-associating domain DUF1422 PF07226.6 KFX97105.1 - 0.19 11.4 4.1 0.31 10.7 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) SecD_SecF PF02355.11 KFX97105.1 - 2.3 7.3 8.1 0.17 11.0 0.5 2.5 2 1 1 3 3 3 0 Protein export membrane protein Glyco_hydro_43 PF04616.9 KFX97107.1 - 3.9e-30 104.9 3.4 1.7e-18 66.7 0.3 2.8 2 1 0 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_68 PF02435.11 KFX97107.1 - 0.33 9.6 3.2 12 4.4 0.0 3.6 3 2 1 4 4 4 0 Levansucrase/Invertase Methyltransf_11 PF08241.7 KFX97108.1 - 1.9e-16 60.3 0.0 2.9e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX97108.1 - 1.1e-13 51.3 0.0 1.6e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX97108.1 - 2.1e-13 50.0 0.0 2.8e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX97108.1 - 4.3e-12 46.5 0.0 7.1e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX97108.1 - 3.4e-10 39.8 0.0 5.9e-10 39.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX97108.1 - 1.5e-08 35.0 0.0 2.4e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX97108.1 - 2.1e-08 34.2 0.0 3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX97108.1 - 1.9e-06 27.1 0.0 7.8e-06 25.1 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KFX97108.1 - 3.8e-06 26.4 0.0 5.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 KFX97108.1 - 2.5e-05 23.4 0.0 3.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 KFX97108.1 - 0.00044 19.7 0.0 0.00055 19.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.15 KFX97108.1 - 0.0019 17.2 0.0 0.0025 16.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase tRNA_U5-meth_tr PF05958.6 KFX97108.1 - 0.0031 16.2 0.0 0.004 15.8 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_16 PF10294.4 KFX97108.1 - 0.0033 16.8 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 KFX97108.1 - 0.071 12.2 0.0 0.099 11.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FokI_C PF02980.11 KFX97108.1 - 0.14 11.8 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 Restriction endonuclease FokI, catalytic domain ADH_N PF08240.7 KFX97109.1 - 6.8e-21 74.0 0.2 1.5e-20 72.9 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX97109.1 - 2.6e-11 43.1 0.2 6.5e-10 38.6 0.0 2.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KFX97109.1 - 7.7e-07 28.4 0.0 1.2e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KFX97109.1 - 6.2e-05 23.1 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.16 KFX97109.1 - 0.00011 21.7 0.1 0.00018 21.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 KFX97109.1 - 0.0046 16.8 0.0 0.0072 16.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KFX97109.1 - 0.089 13.2 0.0 0.24 11.8 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KFX97109.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2346 PF09803.4 KFX97110.1 - 0.00033 20.4 2.8 0.0073 16.1 2.0 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2346) DUF2053 PF09767.4 KFX97110.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2053) ECH PF00378.15 KFX97111.1 - 4.5e-20 71.8 0.0 5.6e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family cwf21 PF08312.7 KFX97112.1 - 1.3e-16 60.1 7.8 1.3e-16 60.1 5.4 2.0 2 0 0 2 2 2 1 cwf21 domain DUF1129 PF06570.6 KFX97112.1 - 0.064 12.5 0.3 0.09 12.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) VIT1 PF01988.14 KFX97112.1 - 4.7 6.6 5.9 8.2 5.8 4.1 1.5 1 1 0 1 1 1 0 VIT family DUF3684 PF12449.3 KFX97113.1 - 1.8e-47 161.6 0.1 2.3e-47 161.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) F-box PF00646.28 KFX97115.1 - 0.0012 18.4 0.0 0.0027 17.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFX97115.1 - 0.056 13.1 0.2 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 F-box-like ABC_tran PF00005.22 KFX97116.1 - 2.2e-50 170.5 0.0 1.5e-28 99.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KFX97116.1 - 5e-33 114.6 35.8 2.7e-22 79.4 13.8 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KFX97116.1 - 1.3e-11 45.0 0.4 0.15 11.9 0.0 4.3 3 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 KFX97116.1 - 2.4e-11 43.3 2.9 0.013 14.7 0.0 4.2 3 1 1 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 KFX97116.1 - 8.3e-08 32.4 0.0 0.0051 16.9 0.0 3.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFX97116.1 - 1.1e-06 28.7 0.2 0.02 14.9 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain DUF258 PF03193.11 KFX97116.1 - 1.7e-06 27.2 0.2 0.0099 15.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFX97116.1 - 7.7e-06 25.3 0.1 0.21 11.1 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 KFX97116.1 - 1.3e-05 25.6 0.0 0.3 11.6 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_25 PF13481.1 KFX97116.1 - 2.2e-05 23.9 0.0 0.42 9.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KFX97116.1 - 5.8e-05 23.5 0.5 0.074 13.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KFX97116.1 - 0.0001 22.2 0.0 0.45 10.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KFX97116.1 - 0.00021 22.1 0.0 0.048 14.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KFX97116.1 - 0.00038 20.4 0.0 0.57 10.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Arch_ATPase PF01637.13 KFX97116.1 - 0.00047 19.9 0.0 0.0061 16.2 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA PF00004.24 KFX97116.1 - 0.00076 19.6 0.4 3.9 7.6 0.0 3.7 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KFX97116.1 - 0.0011 18.4 0.5 1.4 8.2 0.1 2.7 2 0 0 2 2 2 2 AAA-like domain MobB PF03205.9 KFX97116.1 - 0.0027 17.3 0.3 1.1 9.0 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KFX97116.1 - 0.0041 17.4 0.0 1.1 9.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.18 KFX97116.1 - 0.0048 16.7 0.2 1 9.1 0.0 2.5 2 0 0 2 2 2 1 Dynamin family RNA_helicase PF00910.17 KFX97116.1 - 0.0052 16.9 0.0 4.9 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Zeta_toxin PF06414.7 KFX97116.1 - 0.0066 15.5 0.1 3.3 6.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin Adeno_IVa2 PF02456.10 KFX97116.1 - 0.011 14.4 0.3 0.21 10.1 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_14 PF13173.1 KFX97116.1 - 0.013 15.4 0.0 1.1 9.1 0.0 3.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KFX97116.1 - 0.014 15.0 0.2 7.3 6.3 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 KFX97116.1 - 0.059 13.0 0.1 2.2 7.9 0.0 2.6 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.20 KFX97116.1 - 0.063 12.7 2.0 2.5 7.5 0.1 2.8 2 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain ABC_ATPase PF09818.4 KFX97116.1 - 0.073 11.6 0.1 0.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class PRK PF00485.13 KFX97116.1 - 0.096 12.2 0.1 0.3 10.6 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family KAP_NTPase PF07693.9 KFX97116.1 - 0.13 11.2 0.0 1.9 7.4 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain DUF815 PF05673.8 KFX97116.1 - 0.13 11.1 0.0 2.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 KFX97116.1 - 0.16 11.5 0.2 19 4.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain Guanylate_kin PF00625.16 KFX97116.1 - 0.25 10.7 0.1 5.6 6.3 0.0 2.4 2 0 0 2 2 2 0 Guanylate kinase Rad17 PF03215.10 KFX97116.1 - 0.41 9.2 0.1 11 4.5 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DUF1481 PF07356.7 KFX97120.1 - 0.16 11.4 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1481) TAF PF02969.12 KFX97121.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) EXS PF03124.9 KFX97122.1 - 7.1e-96 321.2 9.0 8.1e-96 321.0 6.2 1.0 1 0 0 1 1 1 1 EXS family Pex2_Pex12 PF04757.9 KFX97123.1 - 3.9e-43 147.5 6.8 5.2e-43 147.0 4.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 KFX97123.1 - 1.7e-11 43.7 8.6 3e-11 42.9 6.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFX97123.1 - 1.8e-11 43.8 7.8 3e-11 43.1 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX97123.1 - 7.7e-10 38.2 6.4 1.3e-09 37.5 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFX97123.1 - 2.6e-08 33.3 8.0 3.9e-08 32.8 5.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX97123.1 - 3.4e-08 33.0 5.3 5.4e-08 32.4 3.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KFX97123.1 - 2.1e-06 27.4 7.7 3.7e-06 26.6 5.3 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KFX97123.1 - 0.00017 21.6 7.8 0.00051 20.1 5.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KFX97123.1 - 0.0012 18.6 5.1 0.0024 17.5 3.5 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KFX97123.1 - 0.0037 16.9 6.4 0.0092 15.6 4.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 KFX97123.1 - 0.0088 15.5 1.3 0.016 14.6 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 KFX97123.1 - 0.07 12.7 7.4 0.13 11.8 5.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.16 KFX97123.1 - 1.7 8.5 7.0 5.3 6.9 4.9 1.8 1 1 0 1 1 1 0 IBR domain zf-LYAR PF08790.6 KFX97124.1 - 7.7e-15 54.2 1.2 7.7e-15 54.2 0.8 2.5 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-TRAF PF02176.13 KFX97124.1 - 0.039 14.3 0.6 0.08 13.3 0.4 1.6 1 0 0 1 1 1 0 TRAF-type zinc finger Sugar_tr PF00083.19 KFX97126.1 - 1.7e-127 425.7 26.5 2e-127 425.5 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX97126.1 - 2.5e-21 75.7 40.9 9.3e-18 64.0 10.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Herpes_capsid PF06112.6 KFX97126.1 - 1.7 8.6 4.7 3.8 7.5 3.3 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Metallophos PF00149.23 KFX97127.1 - 2.7e-14 53.0 2.7 1.1e-13 51.0 1.9 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_3 PF00933.16 KFX97128.1 - 6.4e-85 284.7 0.0 1e-84 284.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFX97128.1 - 2.6e-72 243.0 0.0 2.1e-71 240.0 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFX97128.1 - 3.1e-22 78.2 1.5 2.4e-21 75.4 0.2 2.9 3 0 0 3 3 3 1 Fibronectin type III-like domain PA14 PF07691.7 KFX97128.1 - 7.5e-18 64.5 0.0 1.4e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 PA14 domain M60-like PF13402.1 KFX97128.1 - 0.011 14.6 0.0 0.36 9.6 0.0 2.2 2 0 0 2 2 2 0 Peptidase M60-like family DUF202 PF02656.10 KFX97130.1 - 2.3e-16 59.7 2.8 2.8e-16 59.4 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4131 PF13567.1 KFX97130.1 - 0.17 11.2 1.9 0.3 10.4 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF106 PF01956.11 KFX97132.1 - 0.44 10.0 6.0 0.65 9.5 1.2 2.5 3 0 0 3 3 3 0 Integral membrane protein DUF106 YagB_YeeU_YfjZ PF06154.6 KFX97143.1 - 0.014 15.5 0.1 0.042 14.0 0.1 1.7 2 0 0 2 2 2 0 YagB/YeeU/YfjZ family PaaX_C PF08223.6 KFX97143.1 - 0.031 13.9 2.5 6.4 6.4 0.0 2.9 3 0 0 3 3 3 0 PaaX-like protein C-terminal domain MFS_1 PF07690.11 KFX97144.1 - 1.5e-43 148.8 56.5 4.7e-43 147.2 38.5 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX97144.1 - 1.7e-12 46.7 10.6 1.7e-12 46.7 7.3 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter Sod_Cu PF00080.15 KFX97145.1 - 5.9e-15 55.6 0.0 9.2e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 KFX97145.1 - 1.8e-12 47.1 0.0 4.5e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain Apc4_WD40 PF12894.2 KFX97146.1 - 0.0067 15.9 0.0 0.04 13.4 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_2 PF13639.1 KFX97146.1 - 0.3 10.9 7.7 0.035 13.9 1.9 2.0 2 0 0 2 2 2 0 Ring finger domain DUF2361 PF10153.4 KFX97147.1 - 1.6e-39 134.6 8.5 1.6e-39 134.6 5.9 2.5 2 1 1 3 3 3 1 Uncharacterised conserved protein (DUF2361) dsrm PF00035.20 KFX97148.1 - 4e-06 27.2 0.0 7.7e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif NRDE PF05742.7 KFX97149.1 - 5.2e-43 147.3 0.0 1.1e-42 146.2 0.0 1.6 1 1 0 1 1 1 1 NRDE protein DUF1788 PF08747.6 KFX97149.1 - 0.0044 16.8 0.1 0.049 13.4 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1788) Phage_DsbA PF11126.3 KFX97149.1 - 0.019 15.0 0.0 0.056 13.5 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator DsbA Tfb2 PF03849.9 KFX97150.1 - 2.4e-134 447.6 0.0 3.8e-134 446.9 0.0 1.3 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 KFX97150.1 - 5.6e-06 26.1 0.0 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain 4HBT PF03061.17 KFX97151.1 - 8.3e-14 51.4 0.2 1.3e-13 50.8 0.2 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 KFX97151.1 - 0.00011 22.1 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) CDRT4 PF15213.1 KFX97152.1 - 0.06 13.4 0.2 0.074 13.1 0.1 1.1 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein Homeobox PF00046.24 KFX97153.1 - 4.5e-17 61.4 3.2 9.2e-17 60.4 2.2 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFX97153.1 - 0.025 14.2 0.1 0.11 12.2 0.1 2.2 1 0 0 1 1 1 0 Homeobox KN domain Sigma70_ner PF04546.8 KFX97153.1 - 0.19 11.3 6.0 0.37 10.3 4.1 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region 3HCDH PF00725.17 KFX97154.1 - 2e-34 117.8 0.0 3.3e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_N PF02737.13 KFX97154.1 - 6e-32 110.7 0.3 7.8e-32 110.3 0.2 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Iso_dh PF00180.15 KFX97163.1 - 3e-97 325.6 0.0 4.3e-97 325.1 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1447 PF07288.6 KFX97163.1 - 0.11 12.3 0.1 0.31 10.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1447) Ribophorin_II PF05817.9 KFX97164.1 - 3.8e-14 51.8 0.0 5.9e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II p450 PF00067.17 KFX97166.1 - 4.5e-74 249.6 0.0 5.8e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_10 PF13460.1 KFX97167.1 - 7.2e-09 35.8 0.0 9.6e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KFX97167.1 - 0.0032 16.4 0.1 0.012 14.5 0.0 1.9 2 1 1 3 3 3 1 Male sterility protein Epimerase PF01370.16 KFX97167.1 - 0.0051 16.2 0.1 0.024 14.0 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KFX97167.1 - 0.044 14.0 0.0 0.066 13.5 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 KFX97167.1 - 0.065 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Glyco_hydro_25 PF01183.15 KFX97168.1 - 3e-40 137.9 0.6 3.4e-40 137.7 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 APH PF01636.18 KFX97169.1 - 6.5e-18 65.3 1.1 5.6e-17 62.2 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family HAUS6_N PF14661.1 KFX97172.1 - 5.5e-50 170.0 1.5 5.5e-50 170.0 1.0 2.7 3 0 0 3 3 3 1 HAUS augmin-like complex subunit 6 N-terminus HD_3 PF13023.1 KFX97173.1 - 3.3e-45 153.8 0.0 5.2e-45 153.1 0.0 1.3 1 0 0 1 1 1 1 HD domain BAR_2 PF10455.4 KFX97175.1 - 4.6e-57 193.1 1.6 8.1e-57 192.3 1.1 1.3 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KFX97175.1 - 1.1e-17 64.3 5.2 8.6e-17 61.4 3.6 2.0 1 1 0 1 1 1 1 BAR domain Arfaptin PF06456.8 KFX97175.1 - 0.028 13.7 0.1 0.077 12.3 0.1 1.7 1 0 0 1 1 1 0 Arfaptin-like domain FUSC PF04632.7 KFX97175.1 - 2.8 6.2 13.2 2.7 6.3 8.6 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family AIRS PF00586.19 KFX97176.1 - 9.5e-14 51.4 0.0 1.8e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Rhodanese PF00581.15 KFX97176.1 - 1.1e-08 35.3 0.1 1.1e-05 25.7 0.0 2.5 2 0 0 2 2 2 2 Rhodanese-like domain RRM_1 PF00076.17 KFX97177.1 - 2.9e-26 90.8 0.0 7.3e-13 47.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX97177.1 - 2.5e-13 49.7 0.0 1.5e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX97177.1 - 0.002 17.9 0.0 0.35 10.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RIO1 PF01163.17 KFX97178.1 - 2.5e-42 144.3 0.0 5.3e-42 143.3 0.0 1.5 1 1 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 KFX97178.1 - 6.3e-29 99.8 0.1 1.2e-28 99.0 0.1 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 KFX97178.1 - 3.4e-10 40.0 0.2 4e-06 26.7 0.1 3.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFX97178.1 - 5.7e-05 22.2 0.0 0.0066 15.5 0.0 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PC_rep PF01851.17 KFX97179.1 - 3.9e-22 77.1 13.7 3.1e-06 27.0 0.4 8.6 9 0 0 9 9 9 6 Proteasome/cyclosome repeat PPTA PF01239.17 KFX97180.1 - 0.041 13.2 3.5 0.082 12.2 2.4 1.5 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat DNA_mis_repair PF01119.14 KFX97181.1 - 7.6e-33 112.4 0.1 1.7e-32 111.3 0.1 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KFX97181.1 - 2e-15 56.6 0.0 4e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KFX97181.1 - 1.9e-09 37.1 0.0 4.4e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FYVE PF01363.16 KFX97182.1 - 0.096 12.5 5.9 0.18 11.7 4.1 1.7 1 1 0 1 1 1 0 FYVE zinc finger Nbs1_C PF08599.5 KFX97182.1 - 0.11 12.4 0.6 0.21 11.5 0.4 1.5 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 DUF2256 PF10013.4 KFX97182.1 - 0.71 9.6 3.8 0.85 9.4 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DHHA2 PF02833.9 KFX97183.1 - 1.5e-24 86.6 0.0 2.2e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 KFX97183.1 - 5.1e-11 42.4 0.0 9.5e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 DHH family GMC_oxred_N PF00732.14 KFX97183.1 - 0.053 12.6 0.3 0.086 11.9 0.2 1.3 1 0 0 1 1 1 0 GMC oxidoreductase FMO-like PF00743.14 KFX97184.1 - 1.2e-58 198.6 0.0 1.8e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFX97184.1 - 1.5e-26 93.7 0.0 2.1e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFX97184.1 - 4.2e-10 39.8 0.0 6e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX97184.1 - 1.2e-08 34.8 0.2 3.4e-07 30.1 0.0 3.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KFX97184.1 - 3.7e-08 32.6 0.7 1.1e-05 24.5 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KFX97184.1 - 6.3e-08 32.5 0.0 1.5e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFX97184.1 - 3.2e-05 24.2 0.0 0.0073 16.6 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFX97184.1 - 0.00011 21.2 0.0 0.0013 17.6 0.0 2.4 2 1 1 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 KFX97184.1 - 0.00015 20.9 0.2 0.00068 18.7 0.0 2.0 3 0 0 3 3 3 1 Thi4 family NAD_binding_7 PF13241.1 KFX97184.1 - 0.00069 19.8 0.0 0.57 10.4 0.0 2.7 2 2 0 2 2 2 2 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 KFX97184.1 - 0.0039 16.3 0.0 0.27 10.3 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KFX97184.1 - 0.02 14.9 0.1 0.84 9.7 0.0 2.7 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 KFX97184.1 - 0.023 14.0 0.0 0.2 10.9 0.0 2.4 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain SpoU_methylas_C PF12105.3 KFX97184.1 - 0.039 13.5 0.0 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 SpoU, rRNA methylase, C-terminal NAD_binding_2 PF03446.10 KFX97184.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_10 PF13460.1 KFX97184.1 - 0.075 13.0 0.2 0.44 10.5 0.0 2.3 3 0 0 3 3 3 0 NADH(P)-binding HI0933_like PF03486.9 KFX97184.1 - 0.15 10.4 0.0 0.23 9.8 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 KFX97184.1 - 0.15 11.0 0.1 0.47 9.4 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain AATase PF07247.7 KFX97185.1 - 1e-23 83.6 0.0 7.6e-23 80.7 0.0 1.9 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 KFX97185.1 - 1.2e-08 34.1 0.8 9.7e-08 31.2 0.5 1.9 1 1 0 1 1 1 1 Condensation domain WES_acyltransf PF03007.11 KFX97185.1 - 7e-05 22.5 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Spc97_Spc98 PF04130.8 KFX97186.1 - 9.3e-60 202.4 0.0 1e-58 199.0 0.0 2.0 1 1 0 1 1 1 1 Spc97 / Spc98 family ThiF PF00899.16 KFX97188.1 - 3.5e-49 166.1 0.1 1.8e-29 102.3 0.0 2.6 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 KFX97188.1 - 1.3e-39 133.5 3.1 2e-26 91.3 0.2 2.6 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 KFX97188.1 - 2.2e-35 121.5 0.0 1.3e-34 119.0 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 KFX97188.1 - 6e-23 79.9 1.1 2.2e-20 71.7 0.3 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 KFX97188.1 - 0.054 13.6 0.2 0.43 10.6 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 KFX97188.1 - 0.1 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Rad60-SLD_2 PF13881.1 KFX97189.1 - 1.2e-13 50.8 0.0 2.7e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KFX97189.1 - 9.3e-07 28.1 0.0 1.7e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KFX97189.1 - 0.00014 21.9 0.0 0.00031 20.8 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain 7TMR-HDED PF07697.6 KFX97189.1 - 0.14 11.8 1.4 0.21 11.2 0.2 1.8 2 0 0 2 2 2 0 7TM-HD extracellular UMP1 PF05348.6 KFX97190.1 - 2.6e-19 69.4 0.0 3.4e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 ABC_tran PF00005.22 KFX97191.1 - 3.4e-28 98.6 0.0 9.4e-15 55.1 0.0 3.3 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFX97191.1 - 8.7e-15 55.4 0.5 8.6e-08 32.4 0.1 3.2 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KFX97191.1 - 7.3e-07 29.7 2.5 0.054 13.8 1.8 2.2 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KFX97191.1 - 3.3e-05 23.7 0.0 0.0043 16.9 0.0 2.7 3 0 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KFX97191.1 - 6.9e-05 22.2 0.0 0.044 13.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KFX97191.1 - 0.00011 23.0 0.0 0.27 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KFX97191.1 - 0.00083 19.2 0.0 0.96 9.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.1 KFX97191.1 - 0.00093 18.3 0.0 0.16 10.9 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain Miro PF08477.8 KFX97191.1 - 0.0011 19.4 0.0 0.47 10.9 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 KFX97191.1 - 0.0014 18.6 0.0 2 8.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 KFX97191.1 - 0.0041 16.6 0.0 0.44 9.9 0.0 2.7 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_22 PF13401.1 KFX97191.1 - 0.014 15.5 0.0 2.9 8.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 KFX97191.1 - 0.023 14.9 0.0 1.8 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 KFX97191.1 - 0.026 13.8 0.0 2.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_33 PF13671.1 KFX97191.1 - 0.049 13.4 0.0 13 5.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KFX97191.1 - 0.054 13.1 0.0 2 8.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain MobB PF03205.9 KFX97191.1 - 0.06 13.0 0.0 8.4 6.0 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 KFX97191.1 - 0.07 12.6 0.0 2.3 7.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.15 KFX97191.1 - 0.078 11.6 0.0 2.2 6.8 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_25 PF13481.1 KFX97191.1 - 0.082 12.3 0.0 4.6 6.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 KFX97191.1 - 0.098 11.8 0.0 9.7 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 KFX97191.1 - 0.12 11.9 0.1 0.28 10.6 0.0 1.6 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_16 PF13191.1 KFX97191.1 - 0.12 12.3 2.4 9.4 6.1 0.2 3.2 2 2 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 KFX97191.1 - 0.14 11.7 0.0 25 4.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 KFX97191.1 - 0.15 12.0 0.1 29 4.6 0.0 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 KFX97191.1 - 0.16 11.4 0.0 17 4.7 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Tetraspannin PF00335.15 KFX97194.1 - 0.0027 17.0 3.7 0.0032 16.7 0.0 2.5 2 1 0 3 3 3 1 Tetraspanin family K1 PF02960.9 KFX97194.1 - 0.13 12.3 1.6 0.31 11.1 1.1 1.6 1 0 0 1 1 1 0 K1 glycoprotein DUF2273 PF10031.4 KFX97194.1 - 1.3 8.6 5.7 12 5.5 0.0 2.9 3 0 0 3 3 3 0 Small integral membrane protein (DUF2273) DUF1757 PF08560.5 KFX97194.1 - 2.4 7.8 5.2 4 7.1 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1757) Pkinase PF00069.20 KFX97195.1 - 0.012 14.8 0.0 0.15 11.2 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Choline_kinase PF01633.15 KFX97195.1 - 0.05 13.1 0.1 0.09 12.3 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DLH PF01738.13 KFX97198.1 - 2.7e-11 43.1 0.0 3.1e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFX97198.1 - 0.00017 21.3 0.0 0.00026 20.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3712 PF12505.3 KFX97208.1 - 1.9e-20 73.1 1.8 1.9e-20 73.1 1.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Reprolysin_5 PF13688.1 KFX97214.1 - 1.1e-20 74.4 0.4 1.6e-20 73.8 0.3 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KFX97214.1 - 4.6e-16 58.9 0.1 7.2e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KFX97214.1 - 3.3e-11 43.5 0.1 1.8e-10 41.1 0.1 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KFX97214.1 - 0.00076 19.9 0.1 0.0019 18.7 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.14 KFX97214.1 - 0.0025 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide CRM1_C PF08767.6 KFX97215.1 - 7.1e-131 435.8 2.2 9e-131 435.5 0.2 2.2 2 0 0 2 2 2 1 CRM1 C terminal Rgp1 PF08737.5 KFX97215.1 - 4e-124 414.8 0.0 8.7e-124 413.7 0.0 1.6 2 0 0 2 2 2 1 Rgp1 Xpo1 PF08389.7 KFX97215.1 - 9.7e-38 129.3 3.7 9.7e-38 129.3 2.6 2.7 3 1 1 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 KFX97215.1 - 2.4e-11 43.3 0.2 8.9e-11 41.5 0.1 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain HD_assoc PF13286.1 KFX97215.1 - 0.041 14.1 0.2 15 5.9 0.2 3.2 3 0 0 3 3 3 0 Phosphohydrolase-associated domain DUF3385 PF11865.3 KFX97215.1 - 0.11 12.4 2.5 0.15 11.9 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) Arrestin_N PF00339.24 KFX97215.1 - 0.12 12.2 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Calcipressin PF04847.7 KFX97216.1 - 4.8e-48 163.1 0.3 5.9e-48 162.8 0.2 1.1 1 0 0 1 1 1 1 Calcipressin Proteasome PF00227.21 KFX97241.1 - 7.4e-23 80.8 0.0 8.7e-23 80.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.3 KFX97242.1 - 2.1e-18 65.9 0.0 6.2e-18 64.4 0.0 1.9 2 0 0 2 2 2 1 GLUT4 regulating protein TUG UBX PF00789.15 KFX97242.1 - 9.1e-08 32.0 0.2 0.017 15.1 0.0 3.2 3 1 0 3 3 3 2 UBX domain FERM_N PF09379.5 KFX97242.1 - 0.031 14.3 0.0 0.31 11.1 0.0 2.3 2 0 0 2 2 2 0 FERM N-terminal domain PAS_7 PF12860.2 KFX97242.1 - 0.051 13.5 0.2 3.7 7.5 0.0 2.4 2 0 0 2 2 2 0 PAS fold Ribosomal_L36e PF01158.13 KFX97243.1 - 4.8e-47 157.9 11.0 3e-32 110.4 1.5 2.1 2 0 0 2 2 2 2 Ribosomal protein L36e DAGAT PF03982.8 KFX97243.1 - 0.14 10.7 0.1 0.2 10.3 0.0 1.2 1 1 0 1 1 1 0 Diacylglycerol acyltransferase Ribosomal_L41 PF05162.8 KFX97243.1 - 1.4 8.6 13.1 6.3 6.5 1.9 2.8 2 0 0 2 2 2 0 Ribosomal protein L41 IF-2B PF01008.12 KFX97244.1 - 1.7e-72 243.8 0.0 2.8e-72 243.0 0.0 1.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family eIF-3c_N PF05470.7 KFX97244.1 - 0.018 13.1 0.0 0.024 12.7 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus AAA PF00004.24 KFX97245.1 - 8.1e-10 39.0 0.0 1.9e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFX97245.1 - 4.8e-09 36.4 0.0 7e-08 32.6 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFX97245.1 - 5.9e-09 36.1 0.0 1.3e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Cdc6_C PF09079.6 KFX97245.1 - 4.1e-05 23.2 0.1 0.00018 21.1 0.0 2.0 1 1 0 1 1 1 1 CDC6, C terminal NACHT PF05729.7 KFX97245.1 - 0.002 17.8 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 KFX97245.1 - 0.0038 16.9 2.2 0.0066 16.1 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 KFX97245.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KFX97245.1 - 0.063 12.9 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 KFX97245.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 KFX97245.1 - 0.14 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.9 KFX97245.1 - 0.16 10.8 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase WW PF00397.21 KFX97246.1 - 3.6e-09 36.3 0.1 9.7e-09 34.9 0.0 1.8 1 0 0 1 1 1 1 WW domain PhoD PF09423.5 KFX97246.1 - 0.0064 15.1 0.6 0.017 13.6 0.4 1.6 2 0 0 2 2 2 1 PhoD-like phosphatase PMM PF03332.8 KFX97247.1 - 1.8e-103 344.8 0.1 2e-103 344.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase TMPIT PF07851.8 KFX97247.1 - 0.022 13.8 0.1 0.028 13.4 0.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Ank_2 PF12796.2 KFX97254.1 - 2.6e-73 242.4 0.0 6.3e-13 48.8 0.0 7.7 1 1 6 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFX97254.1 - 4e-63 206.2 0.0 3.2e-05 23.4 0.0 12.9 12 0 0 12 12 12 11 Ankyrin repeat Ank_3 PF13606.1 KFX97254.1 - 1.2e-51 167.4 0.0 0.00015 21.6 0.0 12.0 12 0 0 12 12 12 10 Ankyrin repeat Ank_4 PF13637.1 KFX97254.1 - 5.8e-47 157.2 1.2 3.8e-07 30.4 0.0 8.5 3 2 6 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX97254.1 - 5.9e-38 128.0 2.4 6.3e-07 29.4 0.0 8.7 4 1 5 9 9 9 8 Ankyrin repeats (many copies) NACHT PF05729.7 KFX97254.1 - 0.00046 19.8 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KFX97254.1 - 0.0013 18.8 0.0 0.0048 17.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KFX97254.1 - 0.0016 17.5 0.4 0.009 15.1 0.0 2.1 2 0 0 2 2 2 1 KaiC Met_10 PF02475.11 KFX97255.1 - 0.00084 18.9 0.1 0.0032 17.1 0.0 1.8 2 0 0 2 2 2 1 Met-10+ like-protein DEAD PF00270.24 KFX97260.1 - 0.0066 15.9 0.1 0.018 14.5 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase DoxX_2 PF13564.1 KFX97261.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 DoxX-like family SSDP PF04503.8 KFX97263.1 - 1 9.0 8.6 1.1 8.9 6.0 1.1 1 0 0 1 1 1 0 Single-stranded DNA binding protein, SSDP AA_permease_2 PF13520.1 KFX97272.1 - 1.2e-54 185.5 43.4 6.2e-45 153.4 21.3 3.2 2 2 1 3 3 3 2 Amino acid permease RTA1 PF04479.8 KFX97272.1 - 1.6e-28 99.7 1.0 1.6e-28 99.7 0.7 2.6 2 1 0 2 2 2 1 RTA1 like protein AA_permease PF00324.16 KFX97272.1 - 3.9e-12 45.2 37.5 3.9e-12 45.2 26.0 3.0 2 1 0 2 2 2 1 Amino acid permease DUF3092 PF11289.3 KFX97272.1 - 0.022 13.9 1.6 0.046 12.9 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3092) PAN_1 PF00024.21 KFX97273.1 - 0.0004 20.0 14.4 0.012 15.3 0.7 3.1 3 1 0 3 3 3 2 PAN domain PA14_2 PF10528.4 KFX97275.1 - 1.9e-24 85.8 0.1 4.4e-24 84.6 0.1 1.6 1 0 0 1 1 1 1 GLEYA domain Pyr_redox_3 PF13738.1 KFX97275.1 - 3e-22 79.6 0.0 5.5e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase PAN_1 PF00024.21 KFX97275.1 - 1e-08 34.7 14.6 1.4e-05 24.7 1.5 2.6 2 0 0 2 2 2 2 PAN domain PA14 PF07691.7 KFX97275.1 - 8e-05 22.3 0.3 0.00017 21.2 0.2 1.5 1 0 0 1 1 1 1 PA14 domain PAN_4 PF14295.1 KFX97275.1 - 0.00053 19.6 9.2 0.0049 16.5 0.8 2.9 2 0 0 2 2 2 2 PAN domain K_oxygenase PF13434.1 KFX97275.1 - 0.001 18.0 0.0 0.0028 16.6 0.0 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KFX97275.1 - 0.0055 16.6 0.0 0.044 13.6 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase PHO4 PF01384.15 KFX97277.1 - 1.6e-100 335.9 12.5 1.9e-100 335.6 8.7 1.1 1 0 0 1 1 1 1 Phosphate transporter family Glyco_hydro_6 PF01341.12 KFX97298.1 - 0.026 13.9 0.1 0.029 13.8 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 6 SAC3_GANP PF03399.11 KFX97299.1 - 5.3e-08 32.6 0.4 9.7e-08 31.8 0.3 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KFX97299.1 - 0.00049 19.8 0.0 0.00098 18.9 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 HlyIII PF03006.15 KFX97300.1 - 6.7e-59 198.9 14.8 8e-59 198.7 10.3 1.0 1 0 0 1 1 1 1 Haemolysin-III related adh_short PF00106.20 KFX97301.1 - 2e-34 118.9 3.4 2.8e-34 118.4 2.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX97301.1 - 1.1e-23 84.2 0.6 2.2e-23 83.2 0.4 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX97301.1 - 5e-18 65.3 1.7 6.6e-18 65.0 1.1 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KFX97301.1 - 0.0018 17.9 0.9 0.0025 17.4 0.6 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 KFX97301.1 - 0.0074 16.1 1.4 0.01 15.6 0.4 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Gly_rich_SFCGS PF14272.1 KFX97301.1 - 0.033 14.0 1.3 0.74 9.7 0.7 2.4 2 0 0 2 2 2 0 Glycine-rich SFCGS Methyltransf_25 PF13649.1 KFX97301.1 - 0.1 12.9 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 KFX97301.1 - 0.11 11.8 0.4 0.19 11.1 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glycos_transf_2 PF00535.21 KFX97302.1 - 1.8e-28 99.3 0.0 2.3e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KFX97302.1 - 1e-10 41.7 0.0 1.6e-10 41.1 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KFX97302.1 - 3.2e-09 36.2 0.0 4.3e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 KFX97302.1 - 0.0033 17.6 0.0 0.0055 16.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KFX97302.1 - 0.023 13.9 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 TFR_dimer PF04253.10 KFX97303.1 - 3.9e-23 81.3 0.0 7.8e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KFX97303.1 - 2.1e-18 66.7 0.0 3.8e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KFX97303.1 - 3.4e-07 29.9 0.0 5.9e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 KFX97303.1 - 0.053 13.0 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Cyt-b5 PF00173.23 KFX97304.1 - 1.8e-12 46.8 0.0 2.9e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SufE PF02657.10 KFX97304.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Fe-S metabolism associated domain TMA7 PF09072.5 KFX97305.1 - 4.3e-21 75.1 16.4 4.8e-21 74.9 11.4 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Pkinase PF00069.20 KFX97306.1 - 1.2e-52 178.5 0.1 1.8e-52 178.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX97306.1 - 4.1e-24 85.0 0.3 1.2e-23 83.5 0.2 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KFX97306.1 - 0.0078 15.0 0.1 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 KFX97306.1 - 0.056 12.7 0.3 0.14 11.4 0.2 1.7 1 1 0 1 1 1 0 RIO1 family URO-D PF01208.12 KFX97315.1 - 7.6e-119 396.6 0.0 8.6e-119 396.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Ribosomal_L10 PF00466.15 KFX97316.1 - 4.9e-25 87.3 0.0 1.1e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 KFX97316.1 - 4.4e-13 49.4 4.5 1.7e-12 47.5 1.7 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein MutS_V PF00488.16 KFX97317.1 - 1.9e-60 204.2 0.1 3.5e-60 203.3 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFX97317.1 - 1.4e-17 64.1 0.0 3.2e-17 62.9 0.0 1.6 1 1 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 KFX97317.1 - 0.0001 22.3 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 MutS family domain IV AAA_14 PF13173.1 KFX97317.1 - 0.1 12.5 0.0 0.68 9.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain SWIRM PF04433.12 KFX97334.1 - 8e-13 48.3 0.0 4e-12 46.0 0.0 2.0 1 1 0 1 1 1 1 SWIRM domain DUF566 PF04484.7 KFX97334.1 - 0.37 10.2 6.0 0.48 9.8 4.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) ISN1 PF06437.6 KFX97342.1 - 5.9e-61 206.3 0.0 6.6e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Pex16 PF08610.5 KFX97343.1 - 2e-99 332.8 0.1 3.3e-99 332.0 0.0 1.4 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) MFS_1 PF07690.11 KFX97343.1 - 3.5e-37 127.9 22.3 3.5e-37 127.9 15.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX97343.1 - 2.7e-07 29.5 2.7 2.7e-07 29.5 1.8 2.0 3 0 0 3 3 3 1 Sugar (and other) transporter DUF791 PF05631.9 KFX97343.1 - 0.00091 18.0 1.2 0.0017 17.0 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) Nucleos_tra2_N PF01773.15 KFX97343.1 - 0.012 15.9 4.5 2.2 8.6 0.0 3.9 3 0 0 3 3 3 0 Na+ dependent nucleoside transporter N-terminus DUF3895 PF13034.1 KFX97343.1 - 0.15 11.6 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3895) F-box PF00646.28 KFX97344.1 - 3.7e-07 29.6 0.7 6.4e-07 28.8 0.5 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFX97344.1 - 1.7e-05 24.4 1.0 2.9e-05 23.6 0.7 1.4 1 0 0 1 1 1 1 F-box-like SNF2_N PF00176.18 KFX97345.1 - 9e-65 218.4 0.2 1.4e-64 217.7 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFX97345.1 - 5.5e-10 38.9 0.0 1.1e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 KFX97345.1 - 1.6e-07 30.8 3.3 2.9e-07 30.0 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFX97345.1 - 4.7e-07 29.7 5.7 8.9e-07 28.8 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX97345.1 - 7.8e-07 28.6 5.5 1.7e-06 27.5 3.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFX97345.1 - 1.9e-06 27.6 4.8 3.2e-06 26.8 3.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFX97345.1 - 0.00011 21.8 4.3 0.00021 20.9 3.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.24 KFX97345.1 - 0.001 18.6 0.0 0.0026 17.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_UBOX PF13445.1 KFX97345.1 - 0.0013 18.3 2.5 0.003 17.2 1.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFX97345.1 - 0.0017 18.1 7.2 0.0045 16.8 5.0 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KFX97345.1 - 0.11 12.0 3.7 0.28 10.7 2.6 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Fer2 PF00111.22 KFX97345.1 - 0.14 11.8 2.7 0.55 10.0 2.0 1.9 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-MIZ PF02891.15 KFX97345.1 - 0.85 9.1 3.0 2 8.0 2.1 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger BAR PF03114.13 KFX97346.1 - 8.5e-15 54.8 0.2 1.2e-14 54.4 0.1 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 KFX97346.1 - 4.2e-14 51.8 1.0 7.9e-14 50.9 0.2 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KFX97346.1 - 9.9e-13 47.2 0.1 1.7e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFX97346.1 - 1.5e-10 40.3 0.1 2.7e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SID PF11778.3 KFX97346.1 - 0.084 12.7 1.0 3.9 7.3 0.0 2.5 3 0 0 3 3 3 0 Septation initiation DUF4449 PF14613.1 KFX97347.1 - 2.2e-08 34.2 2.4 4.8e-08 33.0 0.2 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) Tricorn_C1 PF14684.1 KFX97347.1 - 0.0013 18.5 0.0 0.0053 16.6 0.0 2.0 1 0 0 1 1 1 1 Tricorn protease C1 domain DUF1828 PF08861.5 KFX97347.1 - 0.0027 17.3 0.0 0.0076 15.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF1828 CPSase_L_D2 PF02786.12 KFX97348.1 - 7.6e-74 247.5 0.0 1.2e-73 246.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 KFX97348.1 - 1.3e-34 118.3 0.0 2.8e-34 117.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 KFX97348.1 - 1.6e-33 115.0 0.1 6.7e-33 113.0 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KFX97348.1 - 2.2e-17 63.4 0.0 4.3e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KFX97348.1 - 3.2e-14 52.3 0.7 1.1e-13 50.6 0.2 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KFX97348.1 - 1.2e-10 40.7 0.0 2.4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KFX97348.1 - 6.9e-09 35.3 0.0 1.5e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus GARS_A PF01071.14 KFX97348.1 - 0.00019 21.0 0.0 0.00045 19.8 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Biotin_lipoyl_2 PF13533.1 KFX97348.1 - 0.0025 17.4 0.0 2.6 7.7 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 KFX97348.1 - 0.011 15.6 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.6 KFX97348.1 - 0.022 14.2 0.0 0.06 12.8 0.0 1.8 1 1 0 1 1 1 0 RimK-like ATP-grasp domain Glyco_hydro_3 PF00933.16 KFX97348.1 - 0.032 13.2 0.0 0.079 11.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 N terminal domain Ank_5 PF13857.1 KFX97348.1 - 0.047 13.9 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DLIC PF05783.6 KFX97349.1 - 2.6e-34 118.7 0.1 1.7e-32 112.7 0.0 2.9 3 0 0 3 3 3 2 Dynein light intermediate chain (DLIC) RRM_1 PF00076.17 KFX97350.1 - 1.3e-18 66.4 0.0 2.4e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX97350.1 - 1.6e-14 53.6 0.0 3.3e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX97350.1 - 7e-08 32.2 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KFX97351.1 - 4.3e-11 42.2 0.4 0.00072 19.3 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat IKI3 PF04762.7 KFX97351.1 - 0.23 9.2 0.0 0.37 8.5 0.0 1.2 1 0 0 1 1 1 0 IKI3 family Septin PF00735.13 KFX97352.1 - 3.4e-106 354.3 0.1 8.4e-106 353.0 0.0 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KFX97352.1 - 5.3e-06 26.3 0.0 1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.8 KFX97352.1 - 0.0005 18.9 0.1 0.00095 18.0 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.18 KFX97352.1 - 0.00081 19.2 7.2 0.011 15.6 0.1 3.0 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 KFX97352.1 - 0.0042 16.5 0.0 0.13 11.6 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KFX97352.1 - 0.013 14.6 0.3 0.039 13.1 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AIG1 PF04548.11 KFX97352.1 - 0.017 14.2 0.0 0.036 13.1 0.0 1.6 1 0 0 1 1 1 0 AIG1 family ABC_tran PF00005.22 KFX97352.1 - 0.017 15.3 0.4 0.1 12.9 0.0 2.4 2 1 0 2 2 2 0 ABC transporter Miro PF08477.8 KFX97352.1 - 0.024 15.1 0.3 0.062 13.8 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AAA_17 PF13207.1 KFX97352.1 - 0.05 14.4 5.6 0.052 14.3 0.2 2.8 2 2 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KFX97352.1 - 0.063 12.6 0.0 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain Pox_A32 PF04665.7 KFX97352.1 - 0.082 12.1 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_24 PF13479.1 KFX97352.1 - 0.11 12.0 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain FMN_bind PF04205.9 KFX97352.1 - 0.16 12.1 0.5 1.1 9.5 0.0 2.4 3 0 0 3 3 3 0 FMN-binding domain FtsK_SpoIIIE PF01580.13 KFX97352.1 - 0.17 11.3 0.2 0.17 11.3 0.1 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 KFX97352.1 - 0.19 11.5 3.2 0.84 9.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF3653 PF12375.3 KFX97352.1 - 0.27 11.4 1.3 6.4 7.0 0.2 2.6 2 1 0 2 2 2 0 Phage protein Bax1-I PF01027.15 KFX97353.1 - 7.5e-49 166.1 28.4 8.7e-49 165.9 19.7 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BaxI_1 PF12811.2 KFX97353.1 - 0.0052 15.9 11.0 0.0094 15.1 7.6 1.4 1 1 0 1 1 1 1 Bax inhibitor 1 like NfeD PF01957.13 KFX97353.1 - 4.4 7.4 12.8 0.74 9.9 0.9 2.8 1 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding SH3_1 PF00018.23 KFX97354.1 - 9.3e-09 34.5 0.1 1.5e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFX97354.1 - 1.1e-06 28.0 0.0 2.1e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFX97354.1 - 3.2e-06 26.5 0.0 6.5e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain LIME1 PF15332.1 KFX97355.1 - 0.071 12.3 0.5 0.098 11.8 0.3 1.3 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 Erythro-docking PF09277.6 KFX97355.1 - 0.092 12.4 0.2 8.3 6.1 0.0 2.6 2 0 0 2 2 2 0 Erythronolide synthase, docking Aa_trans PF01490.13 KFX97356.1 - 1.5e-92 310.2 21.2 2.2e-92 309.6 14.7 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KFX97356.1 - 3.6e-08 32.6 19.8 3.6e-08 32.6 13.8 1.6 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Ribosomal_S16 PF00886.14 KFX97357.1 - 1.2e-25 88.9 0.1 2.1e-25 88.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.10 KFX97358.1 - 1.1e-34 119.5 0.0 1.3e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Ras PF00071.17 KFX97359.1 - 3.9e-52 175.9 0.0 4.6e-52 175.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX97359.1 - 9.1e-21 74.5 0.0 1.4e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFX97359.1 - 1.6e-10 40.4 0.0 1.8e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFX97359.1 - 9.9e-07 28.3 0.0 5.5e-06 25.9 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFX97359.1 - 3e-05 23.9 0.0 5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KFX97359.1 - 0.0043 17.1 0.1 0.041 14.0 0.0 2.4 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFX97359.1 - 0.0049 16.8 0.6 0.49 10.3 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain Gtr1_RagA PF04670.7 KFX97359.1 - 0.024 13.7 0.0 0.031 13.4 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KFX97359.1 - 0.043 12.4 0.0 0.077 11.6 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit AAA_25 PF13481.1 KFX97359.1 - 0.12 11.7 0.1 0.34 10.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain RRM_1 PF00076.17 KFX97360.1 - 3.6e-16 58.5 0.0 7.8e-13 47.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX97360.1 - 1.9e-09 37.3 0.0 2e-06 27.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pro_isomerase PF00160.16 KFX97373.1 - 1.9e-19 70.3 0.0 2.4e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.17 KFX97374.1 - 6.9e-13 48.8 0.0 9.9e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Med3 PF11593.3 KFX97377.1 - 0.11 11.6 9.4 0.13 11.4 6.5 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MFS_1 PF07690.11 KFX97379.1 - 8.1e-07 28.0 16.4 8.1e-07 28.0 11.4 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily FSH1 PF03959.8 KFX97380.1 - 6.8e-31 107.3 0.0 1e-30 106.8 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KFX97380.1 - 6.6e-05 22.4 0.0 0.00079 18.9 0.0 2.0 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KFX97380.1 - 9.4e-05 22.3 2.2 0.00014 21.8 1.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX97380.1 - 0.0012 18.5 0.0 0.0018 18.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KFX97380.1 - 0.039 13.5 0.2 0.78 9.2 0.0 2.4 3 0 0 3 3 3 0 alpha/beta hydrolase fold PE-PPE PF08237.6 KFX97380.1 - 0.064 12.6 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Fungal_trans PF04082.13 KFX97381.1 - 4.1e-13 48.7 0.1 7.3e-13 47.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Kelch_5 PF13854.1 KFX97383.1 - 6.1e-12 45.2 0.1 6.1e-12 45.2 0.1 3.6 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.1 KFX97383.1 - 4.2e-05 23.5 3.3 0.00044 20.3 0.1 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_1 PF01344.20 KFX97383.1 - 0.00078 18.9 3.1 2 8.0 0.2 3.6 3 0 0 3 3 3 2 Kelch motif SKG6 PF08693.5 KFX97383.1 - 0.093 12.0 1.6 0.37 10.1 1.1 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Peptidase_M56 PF05569.6 KFX97383.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 Kelch_6 PF13964.1 KFX97383.1 - 0.27 11.4 5.8 0.98 9.7 0.1 3.8 3 1 0 3 3 3 0 Kelch motif Stm1_N PF09598.5 KFX97384.1 - 1.6e-12 47.9 5.8 1.6e-12 47.9 4.0 4.1 3 2 1 4 4 4 1 Stm1 HABP4_PAI-RBP1 PF04774.10 KFX97384.1 - 0.00086 19.7 4.3 0.00086 19.7 3.0 2.7 2 1 1 3 3 3 1 Hyaluronan / mRNA binding family DOR PF14839.1 KFX97384.1 - 1.6 8.3 6.1 2.8 7.6 4.2 1.3 1 0 0 1 1 1 0 DOR family bZIP_1 PF00170.16 KFX97385.1 - 4.3e-06 26.5 6.1 4.3e-06 26.5 4.3 1.8 2 0 0 2 2 2 1 bZIP transcription factor GvpL_GvpF PF06386.6 KFX97385.1 - 0.026 14.1 2.9 0.046 13.3 2.0 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF bZIP_2 PF07716.10 KFX97385.1 - 0.24 11.2 9.3 0.083 12.7 3.5 2.3 2 0 0 2 2 2 0 Basic region leucine zipper DUF4407 PF14362.1 KFX97385.1 - 0.69 8.8 5.1 1.5 7.7 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) WAC_Acf1_DNA_bd PF10537.4 KFX97392.1 - 2.7e-38 130.2 0.0 1e-37 128.3 0.0 2.1 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 KFX97392.1 - 2.3e-17 62.4 1.6 4.3e-17 61.6 1.1 1.5 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 KFX97392.1 - 2e-11 43.3 0.5 4.3e-11 42.2 0.4 1.6 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 KFX97392.1 - 3.7e-05 23.4 0.1 0.00011 21.9 0.1 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 PMAIP1 PF15150.1 KFX97392.1 - 0.034 13.9 0.0 0.28 10.9 0.0 2.4 2 0 0 2 2 2 0 Phorbol-12-myristate-13-acetate-induced WHIM3 PF15614.1 KFX97392.1 - 0.055 13.2 0.0 0.28 11.0 0.0 2.3 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 3 mRNA_cap_enzyme PF01331.14 KFX97393.1 - 7.4e-46 156.2 0.0 1.1e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain SCA7 PF08313.7 KFX97393.1 - 3.2e-32 109.9 0.8 3.2e-32 109.9 0.6 2.3 2 0 0 2 2 2 1 SCA7, zinc-binding domain mRNA_cap_C PF03919.10 KFX97393.1 - 2.7e-22 79.0 0.3 2.7e-22 79.0 0.2 2.1 3 0 0 3 3 3 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 KFX97393.1 - 0.0007 19.0 0.0 0.023 14.0 0.0 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Ank_2 PF12796.2 KFX97396.1 - 4.4e-117 382.7 8.5 1.9e-16 60.1 0.0 7.7 2 2 8 10 10 10 9 Ankyrin repeats (3 copies) Ank PF00023.25 KFX97396.1 - 1.9e-75 245.1 3.2 3.3e-08 32.9 0.0 15.6 16 0 0 16 16 16 13 Ankyrin repeat Ank_5 PF13857.1 KFX97396.1 - 4.8e-55 182.3 4.4 1.1e-07 31.8 0.0 11.5 5 5 7 12 12 12 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX97396.1 - 2.6e-51 166.4 1.6 0.0019 18.2 0.0 14.6 14 0 0 14 14 14 11 Ankyrin repeat Ank_4 PF13637.1 KFX97396.1 - 5.4e-48 160.5 0.0 3.6e-08 33.6 0.0 8.5 7 1 1 8 8 8 7 Ankyrin repeats (many copies) PRELI PF04707.9 KFX97397.1 - 2.3e-43 147.4 0.6 2.7e-43 147.2 0.4 1.0 1 0 0 1 1 1 1 PRELI-like family DUF647 PF04884.9 KFX97398.1 - 9.3e-75 251.0 0.2 1.2e-74 250.6 0.1 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis HEAT_2 PF13646.1 KFX97400.1 - 1.4e-17 63.7 13.2 7.4e-08 32.5 0.1 7.4 3 2 3 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 KFX97400.1 - 6.6e-17 61.4 16.1 1.3e-08 35.0 0.2 8.9 5 2 4 9 9 9 3 HEAT-like repeat HEAT PF02985.17 KFX97400.1 - 2.9e-16 58.0 9.2 0.0017 18.2 0.0 9.3 9 0 0 9 9 9 3 HEAT repeat Vac14_Fab1_bd PF12755.2 KFX97400.1 - 5e-11 42.8 0.0 0.048 14.0 0.0 5.9 3 1 3 6 6 6 3 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 KFX97400.1 - 3.7e-08 32.5 2.9 8e-07 28.1 0.0 3.7 3 2 2 5 5 5 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 KFX97400.1 - 3.7e-07 29.7 0.9 0.2 10.9 0.0 4.6 3 2 2 5 5 5 2 CLASP N terminal RIX1 PF08167.7 KFX97400.1 - 6e-05 22.7 0.2 0.022 14.4 0.0 4.7 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis Adaptin_N PF01602.15 KFX97400.1 - 0.00047 18.6 0.8 0.039 12.2 0.0 2.4 2 0 0 2 2 2 2 Adaptin N terminal region Arm PF00514.18 KFX97400.1 - 0.0009 18.9 3.7 0.33 10.8 0.1 4.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat CAS_CSE1 PF03378.10 KFX97400.1 - 0.014 13.7 1.2 3.4 5.8 0.0 3.4 4 1 0 4 4 4 0 CAS/CSE protein, C-terminus IBN_N PF03810.14 KFX97400.1 - 0.034 14.0 0.4 0.25 11.2 0.1 2.8 1 1 1 2 2 2 0 Importin-beta N-terminal domain FAA_hydrolase_N PF09298.6 KFX97400.1 - 0.041 13.8 2.4 4.5 7.3 0.0 3.4 4 0 0 4 4 3 0 Fumarylacetoacetase N-terminal DUF3385 PF11865.3 KFX97400.1 - 0.097 12.5 0.4 6.1 6.7 0.0 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF3385) DALR_1 PF05746.10 KFX97400.1 - 0.58 10.1 6.6 6 6.8 0.0 4.2 3 1 1 4 4 4 0 DALR anticodon binding domain adh_short PF00106.20 KFX97401.1 - 9.1e-19 67.9 0.0 2.5e-18 66.5 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFX97401.1 - 3.1e-11 43.2 0.0 4.6e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFX97401.1 - 5.2e-06 26.3 0.0 9.4e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFX97401.1 - 0.00013 21.5 0.0 0.00022 20.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX97401.1 - 0.00045 20.2 0.1 0.0012 18.9 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KFX97401.1 - 0.00056 18.8 0.0 0.00081 18.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 KFX97401.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF3842 PF12953.2 KFX97401.1 - 0.046 13.8 0.2 0.13 12.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3842) DUF3940 PF13076.1 KFX97401.1 - 0.092 12.3 0.7 0.15 11.6 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3940) Shikimate_DH PF01488.15 KFX97401.1 - 0.093 12.8 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.14 KFX97401.1 - 0.16 10.6 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RRM_1 PF00076.17 KFX97404.1 - 7.6e-42 140.8 0.0 5.7e-21 73.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX97404.1 - 8.1e-33 112.2 0.0 5.1e-16 58.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX97404.1 - 6.1e-21 74.0 0.0 9.8e-10 38.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFX97404.1 - 0.0014 18.3 0.0 0.36 10.6 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 KFX97404.1 - 0.02 13.3 34.8 0.023 13.2 24.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ribosomal_L37 PF08561.5 KFX97405.1 - 1.4e-26 91.8 1.4 2.4e-19 68.6 0.1 2.4 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L37 NDUFB10 PF10249.4 KFX97405.1 - 0.045 13.9 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 TAFII55_N PF04658.8 KFX97406.1 - 1.9e-50 170.5 0.0 3.2e-50 169.7 0.0 1.4 1 0 0 1 1 1 1 TAFII55 protein conserved region YgaB PF14182.1 KFX97406.1 - 0.025 14.8 0.2 0.07 13.3 0.1 1.8 1 1 0 1 1 1 0 YgaB-like protein CTD PF12815.2 KFX97406.1 - 0.47 10.8 7.9 8.6 6.8 4.2 2.3 2 0 0 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Alg6_Alg8 PF03155.10 KFX97407.1 - 2.9e-134 448.4 30.3 2e-83 280.8 8.6 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family 2-Hacid_dh_C PF02826.14 KFX97409.1 - 1.5e-52 177.3 0.0 2.7e-52 176.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFX97409.1 - 1.5e-34 118.3 0.3 2.1e-34 117.8 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.20 KFX97409.1 - 0.0011 18.4 0.5 0.0046 16.4 0.0 2.3 2 0 0 2 2 2 1 ACT domain AlaDh_PNT_C PF01262.16 KFX97409.1 - 0.0041 16.6 1.8 0.03 13.9 0.4 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.16 KFX97409.1 - 0.027 14.3 0.2 0.073 12.9 0.1 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.1 KFX97409.1 - 0.034 14.4 0.0 0.092 13.0 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain Lipase_GDSL_2 PF13472.1 KFX97410.1 - 1.9e-15 57.4 0.6 2.6e-15 56.9 0.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFX97410.1 - 1.1e-11 45.0 0.1 1.9e-11 44.2 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KFX97410.1 - 0.00022 20.9 0.0 0.00033 20.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Ribosomal_S8 PF00410.14 KFX97412.1 - 8e-09 35.4 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S8 APH PF01636.18 KFX97426.1 - 9.9e-10 38.5 0.0 3.5e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF4197 PF13852.1 KFX97427.1 - 0.049 13.1 0.6 0.054 13.0 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4197) PUD PF03714.9 KFX97427.1 - 0.071 13.2 0.1 0.08 13.0 0.1 1.1 1 0 0 1 1 1 0 Bacterial pullanase-associated domain RRP7 PF12923.2 KFX97427.1 - 0.14 12.1 4.9 0.18 11.8 3.4 1.1 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) DEAD PF00270.24 KFX97428.1 - 3.7e-08 33.0 0.0 1e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KFX97428.1 - 0.00031 20.6 0.0 0.026 14.3 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit GTP_EFTU PF00009.22 KFX97440.1 - 1e-55 188.1 0.3 1.6e-55 187.4 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KFX97440.1 - 4.2e-33 113.0 0.0 8.3e-33 112.0 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 KFX97440.1 - 1.2e-31 108.7 0.1 2.5e-31 107.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 KFX97440.1 - 2.9e-24 84.7 0.0 5e-23 80.7 0.0 2.5 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KFX97440.1 - 5.2e-13 48.9 0.0 1.2e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF442 PF04273.8 KFX97440.1 - 0.13 12.1 0.1 18 5.2 0.0 3.4 3 0 0 3 3 3 0 Putative phosphatase (DUF442) Abhydrolase_6 PF12697.2 KFX97442.1 - 2.1e-09 37.6 2.2 4.9e-09 36.3 0.7 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX97442.1 - 5.7e-05 22.8 0.0 0.00013 21.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX97442.1 - 0.0018 17.8 0.0 0.0025 17.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KFX97442.1 - 0.012 15.1 0.2 0.023 14.2 0.1 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF1282 PF06930.7 KFX97442.1 - 0.041 13.5 2.0 0.062 12.9 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1282) Abhydrolase_8 PF06259.7 KFX97442.1 - 0.095 12.1 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Aldo_ket_red PF00248.16 KFX97443.1 - 7.9e-58 195.5 0.0 1.5e-57 194.5 0.0 1.5 2 0 0 2 2 2 1 Aldo/keto reductase family Fructosamin_kin PF03881.9 KFX97443.1 - 6.1e-42 143.5 0.1 8.8e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase Abhydrolase_6 PF12697.2 KFX97444.1 - 2.9e-08 33.8 0.1 7.9e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 KFX97444.1 - 1.3e-07 31.1 0.0 3.4e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3312 PF11768.3 KFX97444.1 - 3e-07 29.0 0.0 0.0066 14.7 0.0 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3312) WD40 PF00400.27 KFX97444.1 - 7e-07 28.8 0.0 7.9 6.5 0.0 6.4 6 0 0 6 6 6 1 WD domain, G-beta repeat PGAP1 PF07819.8 KFX97444.1 - 7.6e-05 22.4 0.0 0.00018 21.1 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein NACHT PF05729.7 KFX97444.1 - 0.00028 20.5 0.2 0.0017 18.0 0.0 2.2 2 0 0 2 2 2 1 NACHT domain PQQ_2 PF13360.1 KFX97444.1 - 0.00089 18.7 0.0 0.048 13.1 0.0 2.8 1 1 0 1 1 1 1 PQQ-like domain Abhydrolase_5 PF12695.2 KFX97444.1 - 0.0014 18.4 0.0 0.081 12.6 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family VID27 PF08553.5 KFX97444.1 - 0.068 11.3 0.7 1.6 6.8 0.0 2.4 3 0 0 3 3 3 0 VID27 cytoplasmic protein AAA_22 PF13401.1 KFX97444.1 - 0.1 12.7 0.2 1.1 9.4 0.0 2.6 1 1 1 2 2 2 0 AAA domain TFIIE_beta PF02186.10 KFX97444.1 - 0.11 12.5 0.2 30 4.6 0.0 2.9 2 0 0 2 2 2 0 TFIIE beta subunit core domain DUF842 PF05811.8 KFX97444.1 - 0.13 11.7 0.0 0.35 10.3 0.0 1.7 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) AAA_19 PF13245.1 KFX97444.1 - 0.2 11.4 0.0 0.6 9.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain DAO PF01266.19 KFX97445.1 - 4.1e-35 121.3 1.4 5.6e-35 120.8 1.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KFX97445.1 - 0.00081 19.1 0.1 0.018 14.8 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KFX97445.1 - 0.018 15.0 0.1 0.056 13.4 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KFX97445.1 - 0.019 14.9 0.0 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_transf_54 PF04666.8 KFX97446.1 - 3.1e-09 35.9 0.0 0.0011 17.8 0.1 3.1 3 0 0 3 3 3 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region EF-hand_1 PF00036.27 KFX97446.1 - 1.8e-05 23.7 2.6 0.00016 20.7 0.1 2.8 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 KFX97446.1 - 2.3e-05 23.9 1.1 0.00049 19.7 0.2 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 KFX97446.1 - 0.00012 22.1 0.8 0.00067 19.7 0.5 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KFX97446.1 - 0.00013 21.0 2.4 0.0073 15.6 0.7 2.4 2 0 0 2 2 2 1 EF hand Glyco_transf_25 PF01755.12 KFX97446.1 - 0.082 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) ADH_zinc_N_2 PF13602.1 KFX97447.1 - 4.9e-26 92.0 0.5 1.1e-25 90.9 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KFX97447.1 - 1.2e-16 60.4 0.1 3.1e-16 59.1 0.1 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX97447.1 - 4.4e-06 26.4 0.0 1.3e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pyr_redox PF00070.22 KFX97448.1 - 6.5e-20 71.3 0.3 6.5e-20 71.3 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KFX97448.1 - 1e-19 70.5 0.0 2.1e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 KFX97448.1 - 1.1e-19 71.0 2.3 5e-17 62.4 1.6 3.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFX97448.1 - 5.7e-08 32.0 8.6 0.0015 17.4 0.5 3.6 2 1 2 4 4 4 2 Glucose inhibited division protein A DAO PF01266.19 KFX97448.1 - 3.1e-07 29.6 9.6 0.00016 20.7 0.1 3.3 3 0 0 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFX97448.1 - 3.6e-06 27.2 0.2 0.00087 19.3 0.0 2.9 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFX97448.1 - 5.3e-06 25.5 5.7 0.21 10.4 0.1 3.2 3 0 0 3 3 3 3 Lycopene cyclase protein HI0933_like PF03486.9 KFX97448.1 - 1.7e-05 23.4 9.7 0.0048 15.4 0.2 3.2 2 1 1 3 3 3 2 HI0933-like protein 3HCDH_N PF02737.13 KFX97448.1 - 7.6e-05 22.4 4.3 0.0073 15.9 0.1 2.5 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KFX97448.1 - 0.00049 19.0 4.8 0.013 14.3 0.5 2.6 2 0 0 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.1 KFX97448.1 - 0.0015 18.7 0.6 0.012 15.8 0.1 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 KFX97448.1 - 0.0022 17.1 0.0 0.015 14.4 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 KFX97448.1 - 0.01 14.9 0.6 0.38 9.8 0.0 2.5 2 0 0 2 2 2 0 Thi4 family UDPG_MGDP_dh_N PF03721.9 KFX97448.1 - 0.037 13.4 2.4 0.49 9.7 0.1 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.1 KFX97448.1 - 0.064 13.5 0.4 0.17 12.2 0.0 1.9 2 0 0 2 2 1 0 XdhC Rossmann domain DFP PF04127.10 KFX97448.1 - 0.066 12.8 0.6 0.75 9.3 0.1 2.3 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein NAD_binding_8 PF13450.1 KFX97448.1 - 0.071 13.1 3.2 2.5 8.1 0.3 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 KFX97448.1 - 0.073 13.0 0.6 0.48 10.4 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain zf-C2H2_4 PF13894.1 KFX97449.1 - 3.4e-12 45.7 27.2 0.0011 19.0 1.5 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.21 KFX97449.1 - 3.2e-11 42.8 28.0 0.0057 16.9 2.7 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFX97449.1 - 0.00015 21.9 28.4 0.035 14.4 0.4 4.8 5 0 0 5 5 5 3 Zinc-finger double domain DUF629 PF04780.7 KFX97449.1 - 6.7 5.1 12.6 0.48 8.8 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF629) Pro_dh PF01619.13 KFX97451.1 - 5.6e-38 130.6 1.3 8.3e-38 130.1 0.9 1.2 1 0 0 1 1 1 1 Proline dehydrogenase BetaGal_dom3 PF13363.1 KFX97451.1 - 0.12 11.7 0.3 0.51 9.7 0.0 2.0 2 0 0 2 2 2 0 Beta-galactosidase, domain 3 DUF2477 PF10631.4 KFX97453.1 - 0.1 12.8 2.3 0.18 12.0 1.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2477) DUF1127 PF06568.6 KFX97454.1 - 0.12 11.7 4.8 0.2 11.1 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) He_PIG PF05345.7 KFX97460.1 - 5e-16 58.4 18.3 5.2e-06 26.3 2.2 4.8 4 0 0 4 4 4 4 Putative Ig domain Methyltransf_16 PF10294.4 KFX97461.1 - 2.6e-46 157.2 0.0 3.8e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Dirigent PF03018.9 KFX97461.1 - 0.011 15.3 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Dirigent-like protein Methyltransf_18 PF12847.2 KFX97461.1 - 0.12 12.9 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain 4HBT_3 PF13622.1 KFX97461.1 - 2.9 7.5 10.0 2.7 7.6 2.9 2.3 2 0 0 2 2 2 0 Thioesterase-like superfamily GMC_oxred_N PF00732.14 KFX97462.1 - 1.1e-22 80.5 0.0 8.9e-19 67.7 0.0 2.8 2 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 KFX97462.1 - 1.7e-12 47.8 0.1 3.7e-12 46.7 0.1 1.7 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KFX97462.1 - 5.1e-06 25.6 2.4 0.0008 18.3 1.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KFX97462.1 - 3.4e-05 22.9 0.9 0.00032 19.7 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFX97462.1 - 0.00019 21.5 0.1 0.048 13.7 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFX97462.1 - 0.00088 19.1 0.4 0.0016 18.3 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX97462.1 - 0.0012 18.8 0.3 0.0032 17.4 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KFX97462.1 - 0.0019 16.7 0.2 0.0028 16.2 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 KFX97462.1 - 0.0023 17.0 0.2 0.0041 16.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 KFX97462.1 - 0.0076 15.3 0.4 0.045 12.8 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KFX97462.1 - 0.011 14.7 0.5 0.016 14.1 0.4 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 KFX97462.1 - 0.027 13.3 0.1 0.039 12.8 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KFX97462.1 - 0.15 11.0 0.2 0.22 10.5 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain ABC_tran PF00005.22 KFX97470.1 - 1.6e-49 167.7 0.0 4.6e-30 104.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KFX97470.1 - 3.8e-30 105.2 22.7 4.4e-16 59.1 5.6 3.7 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 KFX97470.1 - 2e-10 40.2 0.0 0.0014 17.8 0.0 4.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFX97470.1 - 4.8e-06 26.7 1.6 0.51 10.2 0.0 4.5 2 2 0 2 2 2 1 AAA domain T2SE PF00437.15 KFX97470.1 - 1.1e-05 24.5 0.0 0.016 14.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 KFX97470.1 - 3.2e-05 23.4 0.1 0.057 12.8 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 KFX97470.1 - 6.6e-05 23.3 0.1 0.0047 17.2 0.0 2.7 3 0 0 3 3 3 1 AAA domain RIO1 PF01163.17 KFX97470.1 - 0.00012 21.5 0.1 0.00021 20.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family AAA_29 PF13555.1 KFX97470.1 - 0.00016 21.1 0.2 0.69 9.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KFX97470.1 - 0.00092 19.2 4.9 0.23 11.4 0.1 3.3 4 0 0 4 4 3 2 AAA ATPase domain Miro PF08477.8 KFX97470.1 - 0.0016 18.9 0.2 3.8 8.0 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein APH PF01636.18 KFX97470.1 - 0.0018 18.0 0.1 0.016 14.9 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF258 PF03193.11 KFX97470.1 - 0.0046 16.1 0.0 2.2 7.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Kdo PF06293.9 KFX97470.1 - 0.0055 15.8 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_22 PF13401.1 KFX97470.1 - 0.0086 16.2 0.0 5.3 7.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 KFX97470.1 - 0.0091 15.1 0.0 1.8 7.5 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin MMR_HSR1 PF01926.18 KFX97470.1 - 0.011 15.6 0.1 0.63 10.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Pkinase PF00069.20 KFX97470.1 - 0.012 14.7 0.0 0.022 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain DUF87 PF01935.12 KFX97470.1 - 0.013 15.3 1.8 0.35 10.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_10 PF12846.2 KFX97470.1 - 0.024 14.1 0.1 5.6 6.3 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain DUF2075 PF09848.4 KFX97470.1 - 0.07 12.0 0.1 0.66 8.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 KFX97470.1 - 1.2 8.7 3.5 1.5 8.4 0.1 2.7 3 0 0 3 3 3 0 NACHT domain cobW PF02492.14 KFX97470.1 - 1.8 7.9 4.0 1.7 8.0 0.5 2.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Raffinose_syn PF05691.7 KFX97471.1 - 1.4e-48 165.0 1.3 3.1e-46 157.3 1.0 2.3 2 1 0 2 2 2 1 Raffinose synthase or seed imbibition protein Sip1 Melibiase PF02065.13 KFX97471.1 - 8.4e-05 21.4 0.4 0.00014 20.6 0.3 1.3 1 0 0 1 1 1 1 Melibiase tRNA-synt_1b PF00579.20 KFX97472.1 - 1.8e-75 253.8 0.0 2.4e-75 253.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TFIID_20kDa PF03847.8 KFX97474.1 - 1.1e-22 80.0 0.0 1.6e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 KFX97474.1 - 0.00042 20.3 0.1 0.0011 18.9 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFX97474.1 - 0.0038 17.3 0.0 0.0062 16.6 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 KFX97474.1 - 0.15 11.8 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit KTI12 PF08433.5 KFX97485.1 - 1.1e-55 188.7 0.0 2e-55 187.8 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 TPP_enzyme_N PF02776.13 KFX97487.1 - 3.6e-40 137.2 0.0 1e-39 135.7 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KFX97487.1 - 3.4e-33 114.2 0.1 7.3e-33 113.2 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KFX97487.1 - 6.2e-20 71.3 0.0 1.7e-19 69.8 0.0 1.8 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 KFX97487.1 - 0.037 13.5 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit SH3BGR PF04908.10 KFX97488.1 - 0.00022 21.0 0.0 0.00084 19.2 0.0 2.0 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Astro_capsid PF03115.9 KFX97488.1 - 2.2 6.4 15.8 2.8 6.1 11.0 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Nop14 PF04147.7 KFX97488.1 - 5.2 4.8 52.6 6.8 4.4 36.4 1.1 1 0 0 1 1 1 0 Nop14-like family 3Beta_HSD PF01073.14 KFX97489.1 - 3.1e-68 229.5 0.0 3.9e-68 229.1 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KFX97489.1 - 2.3e-28 99.2 0.1 3.1e-28 98.7 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KFX97489.1 - 2.8e-15 55.9 0.1 3.7e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KFX97489.1 - 2.2e-14 53.0 0.2 8.2e-12 44.5 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KFX97489.1 - 1.2e-11 44.9 0.0 1.7e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KFX97489.1 - 5.6e-10 38.6 0.5 1.4e-09 37.3 0.3 1.6 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KFX97489.1 - 9.1e-07 28.9 0.1 1.8e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 KFX97489.1 - 0.00011 21.5 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 KFX97489.1 - 0.00043 19.9 0.0 0.001 18.7 0.0 1.6 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 KFX97489.1 - 0.0014 18.5 0.0 0.0036 17.2 0.0 1.6 1 1 0 1 1 1 1 TrkA-N domain NAD_binding_3 PF03447.11 KFX97489.1 - 0.0032 17.8 0.0 0.006 16.9 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Guanylate_kin PF00625.16 KFX97489.1 - 0.0068 15.8 0.0 0.02 14.3 0.0 1.7 2 0 0 2 2 2 1 Guanylate kinase Glyco_trans_4_2 PF13477.1 KFX97489.1 - 0.018 14.8 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like DapB_N PF01113.15 KFX97489.1 - 0.019 14.8 0.2 0.036 13.9 0.2 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ELMO_CED12 PF04727.8 KFX97490.1 - 5.8e-46 156.1 0.1 1.2e-45 155.1 0.0 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 KFX97490.1 - 0.001 18.7 0.0 0.038 13.7 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) CBM_1 PF00734.13 KFX97491.1 - 1.4e-09 37.4 15.5 1.4e-09 37.4 10.7 2.5 3 0 0 3 3 3 1 Fungal cellulose binding domain Abhydrolase_6 PF12697.2 KFX97491.1 - 9.5e-06 25.6 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFX97491.1 - 1.3e-05 24.5 0.1 2.2e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 KFX97491.1 - 1.8e-05 24.3 1.0 0.00015 21.3 0.7 2.1 1 1 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KFX97491.1 - 6.5e-05 22.7 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KFX97491.1 - 0.0002 20.6 0.1 0.00041 19.6 0.0 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.11 KFX97491.1 - 0.0011 18.5 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 KFX97491.1 - 0.0049 16.4 0.3 0.015 14.8 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold LtrA PF06772.6 KFX97492.1 - 2.5e-20 72.7 23.7 4e-20 72.0 16.4 1.3 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF2666 PF10869.3 KFX97492.1 - 0.072 13.1 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) PsaL PF02605.10 KFX97492.1 - 0.11 11.9 2.7 1.1 8.8 0.9 2.8 2 1 0 2 2 2 0 Photosystem I reaction centre subunit XI Baculo_PEP_C PF04513.7 KFX97492.1 - 0.12 12.1 3.5 0.57 10.0 2.4 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Alpha-amylase PF00128.19 KFX97493.1 - 4.5e-27 95.2 0.0 6.9e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 KFX97493.1 - 5.3e-10 39.3 0.2 1.4e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain MFS_1 PF07690.11 KFX97494.1 - 1.3e-23 83.2 56.7 2.5e-23 82.3 39.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX97494.1 - 0.25 9.8 37.1 0.051 12.1 7.7 2.3 1 1 0 2 2 2 0 Sugar (and other) transporter LAM_C PF12544.3 KFX97495.1 - 0.00015 21.8 0.0 0.00039 20.4 0.0 1.7 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Fer4_14 PF13394.1 KFX97495.1 - 0.0085 16.1 0.0 0.021 14.8 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Radical_SAM PF04055.16 KFX97495.1 - 0.026 14.6 0.1 0.11 12.6 0.1 2.2 2 1 0 2 2 2 0 Radical SAM superfamily zf-GRF PF06839.7 KFX97496.1 - 7.6e-10 38.5 5.4 1.7e-09 37.4 3.7 1.6 1 0 0 1 1 1 1 GRF zinc finger Osmo_CC PF08946.5 KFX97496.1 - 0.054 13.5 0.6 0.054 13.5 0.4 1.9 2 0 0 2 2 2 0 Osmosensory transporter coiled coil FAD_binding_2 PF00890.19 KFX97497.1 - 9.2e-126 420.0 3.3 1.2e-125 419.7 2.3 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 KFX97497.1 - 3.1e-47 159.6 0.6 4.6e-47 159.0 0.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 KFX97497.1 - 2.6e-07 30.7 0.0 0.0025 17.7 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFX97497.1 - 9.1e-06 24.7 0.8 0.0099 14.7 1.2 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 KFX97497.1 - 1.4e-05 24.3 0.4 0.0085 15.2 0.0 2.4 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 KFX97497.1 - 0.00041 19.3 0.1 0.0047 15.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KFX97497.1 - 0.0047 16.0 0.7 0.0076 15.3 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KFX97497.1 - 0.084 11.3 1.7 0.26 9.7 0.4 2.2 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.1 KFX97497.1 - 0.33 10.9 1.8 1.2 9.1 0.2 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF3818 PF12825.2 KFX97498.1 - 6e-134 446.0 6.1 1.2e-133 445.0 4.3 1.5 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KFX97498.1 - 2.6e-42 143.6 0.8 6.3e-42 142.4 0.6 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.19 KFX97498.1 - 3e-07 30.2 1.1 8.1e-07 28.8 0.2 2.3 2 1 0 2 2 2 1 PX domain Myc_N PF01056.13 KFX97498.1 - 0.0056 15.8 1.9 0.012 14.7 1.3 1.5 1 0 0 1 1 1 1 Myc amino-terminal region eIF-5a PF01287.15 KFX97503.1 - 8e-13 48.1 0.1 1.7e-12 47.1 0.1 1.4 2 0 0 2 2 2 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 KFX97503.1 - 0.0056 16.5 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain 3HCDH_N PF02737.13 KFX97504.1 - 2.8e-08 33.6 0.5 3.5e-08 33.2 0.4 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KFX97504.1 - 0.0007 19.4 0.1 0.00089 19.1 0.1 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.19 KFX97504.1 - 0.00083 18.3 0.9 0.0011 17.9 0.6 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 KFX97504.1 - 0.0082 15.3 0.0 0.0082 15.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 KFX97504.1 - 0.04 13.3 0.5 0.05 13.0 0.3 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 KFX97504.1 - 0.049 13.3 0.2 0.064 12.9 0.1 1.2 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_8 PF13450.1 KFX97504.1 - 0.071 13.1 0.3 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain F420_oxidored PF03807.12 KFX97504.1 - 0.072 13.5 0.2 0.12 12.7 0.2 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_3 PF13738.1 KFX97504.1 - 0.084 12.9 0.6 0.11 12.5 0.4 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Saccharop_dh PF03435.13 KFX97504.1 - 0.096 11.6 0.2 0.11 11.4 0.2 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 KFX97504.1 - 0.13 11.6 0.1 0.16 11.3 0.1 1.1 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 KFX97504.1 - 0.13 12.6 0.2 0.18 12.2 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TIMELESS PF04821.9 KFX97505.1 - 1e-90 303.6 0.0 1e-90 303.6 0.0 1.8 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.8 KFX97505.1 - 1.4e-33 116.6 3.1 1.4e-33 116.6 2.1 2.9 2 1 1 3 3 3 2 Timeless protein C terminal region KAP PF05804.7 KFX97506.1 - 0.00012 20.1 0.0 0.015 13.2 0.0 2.1 2 0 0 2 2 2 2 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 KFX97506.1 - 0.016 14.3 0.0 0.042 12.9 0.0 1.6 1 0 0 1 1 1 0 V-ATPase subunit H CDRN PF05174.7 KFX97506.1 - 0.9 9.0 3.7 19 4.8 0.0 3.8 4 0 0 4 4 4 0 Cysteine-rich D. radiodurans N terminus DPM3 PF08285.6 KFX97507.1 - 3.6e-33 113.2 0.1 4.9e-33 112.8 0.1 1.2 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) CENP-P PF13096.1 KFX97508.1 - 0.0016 17.8 0.0 0.0016 17.8 0.0 1.0 1 0 0 1 1 1 1 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P bZIP_1 PF00170.16 KFX97509.1 - 1.8e-08 34.2 8.1 3.4e-08 33.3 5.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFX97509.1 - 3.1e-05 23.6 7.9 8.5e-05 22.2 5.5 1.8 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFX97509.1 - 0.00037 20.7 9.6 0.0008 19.6 6.6 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Med3 PF11593.3 KFX97509.1 - 0.0057 15.9 10.9 0.0057 15.9 7.5 2.3 2 1 0 2 2 2 1 Mediator complex subunit 3 fungal TFIIA PF03153.8 KFX97509.1 - 1.1 9.0 14.8 1.5 8.6 10.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit tRNA-synt_2 PF00152.15 KFX97532.1 - 2.3e-44 151.5 0.0 5.9e-44 150.1 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KFX97532.1 - 0.00058 19.6 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2263 PF10021.4 KFX97533.1 - 6.4e-24 84.6 0.0 9.4e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Fungal_trans PF04082.13 KFX97534.1 - 2.5e-11 42.9 0.8 5.6e-11 41.8 0.5 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KFX97535.1 - 7.2e-24 84.1 58.4 1.8e-18 66.3 18.7 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFX97535.1 - 0.0016 18.1 7.5 0.038 13.7 0.1 4.3 5 1 0 5 5 5 2 MFS_1 like family DUF3704 PF12488.3 KFX97535.1 - 0.07 12.7 2.6 0.2 11.2 1.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3704) RAP1 PF07218.6 KFX97536.1 - 0.01 13.9 12.0 0.012 13.7 8.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_S64 PF08192.6 KFX97536.1 - 0.74 8.0 19.3 0.88 7.8 13.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 Sugar_tr PF00083.19 KFX97537.1 - 1.2e-56 192.2 27.7 1.4e-56 191.9 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX97537.1 - 3.9e-22 78.4 27.0 5.5e-22 77.9 18.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hyd_65N_2 PF14498.1 KFX97538.1 - 3.8e-64 216.5 0.0 5.2e-64 216.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_1 PF00232.13 KFX97539.1 - 1.1e-146 488.6 0.4 1.3e-146 488.3 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 KFX97539.1 - 0.015 14.6 0.0 0.041 13.2 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase catalytic core Sulfatase PF00884.18 KFX97541.1 - 1.5e-15 57.2 0.0 2.6e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KFX97541.1 - 2.1e-06 27.3 0.6 4.1e-06 26.3 0.1 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KFX97541.1 - 0.11 10.9 0.1 0.16 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Zn_clus PF00172.13 KFX97542.1 - 0.00071 19.4 19.1 0.0013 18.6 13.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX97543.1 - 2.9e-17 62.3 0.0 5.3e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KFX97544.1 - 2.8e-17 62.4 21.1 4.3e-15 55.2 9.8 2.3 3 0 0 3 3 3 2 Major Facilitator Superfamily WD40 PF00400.27 KFX97549.1 - 1.6e-27 94.3 6.4 8e-07 28.7 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Myosin_TH1 PF06017.8 KFX97549.1 - 0.19 10.9 0.1 3.1 7.0 0.0 2.1 2 0 0 2 2 2 0 Myosin tail Beta-lactamase PF00144.19 KFX97558.1 - 1.3e-41 142.7 0.1 1.7e-41 142.3 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 KFX97558.1 - 0.014 14.6 0.4 0.024 13.9 0.3 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Ycf4 PF02392.11 KFX97559.1 - 0.13 11.6 1.0 0.19 11.0 0.7 1.2 1 0 0 1 1 1 0 Ycf4 GMC_oxred_N PF00732.14 KFX97561.1 - 6.6e-27 94.4 0.1 1.3e-26 93.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFX97561.1 - 3e-22 79.4 0.1 5.4e-22 78.6 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KFX97561.1 - 1.5e-08 33.9 0.1 0.0039 16.0 0.0 2.5 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KFX97561.1 - 2e-05 23.6 0.4 0.0017 17.3 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFX97561.1 - 0.00082 19.3 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX97561.1 - 0.00097 19.1 0.1 0.0037 17.2 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KFX97561.1 - 0.0029 17.7 0.3 0.019 15.0 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFX97561.1 - 0.01 14.9 0.1 0.026 13.5 0.1 1.6 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 KFX97561.1 - 0.021 13.8 0.1 0.12 11.4 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KFX97561.1 - 0.027 12.9 0.0 0.04 12.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 KFX97561.1 - 0.032 14.6 0.0 0.085 13.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFX97561.1 - 0.68 8.7 3.2 0.88 8.3 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A Glyco_hydro_61 PF03443.9 KFX97562.1 - 5.9e-67 225.6 0.3 7.4e-67 225.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF3446 PF11928.3 KFX97562.1 - 1.6 9.0 7.3 0.52 10.5 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3446) Glyco_hydro_61 PF03443.9 KFX97563.1 - 2.9e-46 158.0 0.0 3.7e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_6 PF01341.12 KFX97564.1 - 1.3e-109 366.2 4.1 1.7e-109 365.8 2.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 KFX97564.1 - 1.1e-12 47.3 12.9 1.1e-12 47.3 8.9 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KFX97564.1 - 3.8 7.6 10.9 0.051 13.6 1.6 2.3 3 0 0 3 3 3 0 Toxin 7 Glyco_hydro_61 PF03443.9 KFX97565.1 - 4.6e-38 131.2 0.0 6.7e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cpn60_TCP1 PF00118.19 KFX97567.1 - 5.8e-136 453.9 2.4 6.6e-136 453.7 1.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1762 PF08574.5 KFX97570.1 - 4.1e-05 23.9 14.1 4.1e-05 23.9 9.7 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF1762) SMI1_KNR4 PF09346.5 KFX97571.1 - 0.028 14.4 0.0 0.077 13.0 0.0 1.8 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) GST_N_3 PF13417.1 KFX97572.1 - 2.4e-10 40.5 0.1 5.6e-10 39.3 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFX97572.1 - 2.1e-08 34.0 0.0 3.7e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFX97572.1 - 0.00011 22.0 0.0 0.00027 20.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFX97572.1 - 0.0049 17.3 0.0 0.0083 16.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.8 KFX97572.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Prefoldin_2 PF01920.15 KFX97573.1 - 3.6 7.4 10.3 38 4.0 0.8 3.4 3 0 0 3 3 3 0 Prefoldin subunit FA_desaturase PF00487.19 KFX97576.1 - 5.6e-27 94.8 22.3 1.7e-26 93.2 15.5 1.7 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KFX97576.1 - 3.7e-06 26.9 0.0 6.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) ABC_tran PF00005.22 KFX97579.1 - 5.4e-33 114.1 0.1 3.4e-20 72.7 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 KFX97579.1 - 1.5e-22 79.1 4.9 8.4e-21 73.6 2.2 2.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 KFX97579.1 - 1e-14 55.1 0.0 0.00042 20.3 0.0 3.3 3 0 0 3 3 3 3 AAA domain AAA_23 PF13476.1 KFX97579.1 - 1.1e-09 38.9 3.5 0.0012 19.2 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KFX97579.1 - 7.8e-09 34.9 0.5 0.00033 20.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KFX97579.1 - 6.2e-07 28.7 0.1 0.00069 18.8 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SMC_N PF02463.14 KFX97579.1 - 6.3e-06 25.5 0.0 0.21 10.7 0.0 3.4 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KFX97579.1 - 6.7e-06 26.9 1.2 0.051 14.3 0.0 3.1 3 0 0 3 3 3 2 AAA domain Miro PF08477.8 KFX97579.1 - 1.9e-05 25.1 0.0 0.064 13.7 0.0 2.9 3 0 0 3 3 2 2 Miro-like protein RNA_helicase PF00910.17 KFX97579.1 - 3.4e-05 23.9 2.5 0.67 10.1 0.0 3.4 3 0 0 3 3 3 2 RNA helicase AAA_18 PF13238.1 KFX97579.1 - 4e-05 23.9 0.7 0.31 11.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 KFX97579.1 - 0.00015 21.7 0.0 0.19 11.6 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.1 KFX97579.1 - 0.00021 21.2 0.1 0.14 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KFX97579.1 - 0.00022 20.9 0.7 0.66 9.6 0.1 2.6 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.1 KFX97579.1 - 0.00027 20.1 0.0 0.26 10.3 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KFX97579.1 - 0.00031 20.8 0.0 0.74 9.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KFX97579.1 - 0.00054 19.4 0.1 0.093 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KFX97579.1 - 0.00097 18.6 1.4 0.075 12.4 0.3 2.5 2 0 0 2 2 2 1 AAA-like domain AAA PF00004.24 KFX97579.1 - 0.0011 19.1 0.1 1 9.5 0.1 3.3 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFX97579.1 - 0.0012 18.6 0.2 0.44 10.2 0.1 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KFX97579.1 - 0.0016 18.4 2.0 0.52 10.2 0.1 3.1 3 1 1 4 4 4 1 AAA ATPase domain AAA_33 PF13671.1 KFX97579.1 - 0.0019 18.0 0.3 0.94 9.3 0.1 3.2 3 0 0 3 3 3 1 AAA domain VirE PF05272.6 KFX97579.1 - 0.0036 16.8 0.1 3.1 7.2 0.0 3.0 3 0 0 3 3 3 1 Virulence-associated protein E MobB PF03205.9 KFX97579.1 - 0.0064 16.2 0.3 0.11 12.2 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 KFX97579.1 - 0.0085 15.8 0.2 7.1 6.2 0.0 2.9 3 0 0 3 3 3 0 Archaeal ATPase NB-ARC PF00931.17 KFX97579.1 - 0.01 14.7 0.1 1.7 7.4 0.1 3.2 3 0 0 3 3 3 0 NB-ARC domain DUF2813 PF11398.3 KFX97579.1 - 0.01 14.9 0.4 4.1 6.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) AAA_14 PF13173.1 KFX97579.1 - 0.011 15.6 0.0 2.9 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.4 KFX97579.1 - 0.013 14.4 1.4 2.3 7.0 0.0 3.0 3 1 1 4 4 4 0 Mitochondrial ribosomal death-associated protein 3 AAA_24 PF13479.1 KFX97579.1 - 0.019 14.5 0.8 4 6.9 0.1 3.0 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.1 KFX97579.1 - 0.025 14.1 3.1 0.63 9.5 0.0 3.2 3 0 0 3 3 3 0 AAA domain ArgK PF03308.11 KFX97579.1 - 0.027 13.2 0.4 3.4 6.3 0.0 2.7 3 0 0 3 3 3 0 ArgK protein PduV-EutP PF10662.4 KFX97579.1 - 0.048 13.1 0.9 10 5.6 0.0 3.2 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 KFX97579.1 - 0.057 12.6 0.1 2.2 7.5 0.0 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B DUF815 PF05673.8 KFX97579.1 - 0.062 12.2 0.5 8.2 5.2 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF815) Rad17 PF03215.10 KFX97579.1 - 0.092 11.4 0.7 10 4.6 0.0 2.7 3 0 0 3 3 3 0 Rad17 cell cycle checkpoint protein NTPase_1 PF03266.10 KFX97579.1 - 0.28 10.8 2.4 2.4 7.8 0.1 2.8 3 0 0 3 3 3 0 NTPase Dynamin_N PF00350.18 KFX97579.1 - 1 9.1 6.5 4.2 7.1 0.0 3.4 4 1 1 5 5 4 0 Dynamin family Zn_clus PF00172.13 KFX97580.1 - 2.3e-05 24.2 9.4 3.9e-05 23.4 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KFX97581.1 - 4.5e-42 144.0 42.6 1e-41 142.8 29.5 1.7 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX97581.1 - 2.6e-11 42.8 17.8 2.6e-11 42.8 12.3 2.6 2 0 0 2 2 2 1 Sugar (and other) transporter DUF1129 PF06570.6 KFX97581.1 - 1.6 8.0 9.3 1.5 8.1 1.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) DUF2530 PF10745.4 KFX97581.1 - 5.9 6.9 15.4 2.3 8.2 1.2 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2530) Fungal_trans PF04082.13 KFX97582.1 - 3.3e-09 35.9 0.0 4.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX97582.1 - 6.5e-09 35.5 9.3 1.4e-08 34.5 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KFX97582.1 - 0.12 12.5 8.8 0.34 11.1 6.1 1.7 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region adh_short PF00106.20 KFX97583.1 - 2.7e-23 82.7 1.1 2.8e-23 82.6 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX97583.1 - 2.3e-10 40.6 0.0 3.1e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX97583.1 - 8.8e-10 38.5 0.1 1.7e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFX97583.1 - 7e-06 25.6 0.1 1.3e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX97583.1 - 2.4e-05 24.4 0.0 8.1e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 KFX97583.1 - 0.00046 19.4 0.0 0.00054 19.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 KFX97583.1 - 0.01 14.7 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.8 KFX97583.1 - 0.015 14.5 0.1 0.023 13.9 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family ETF_alpha PF00766.14 KFX97583.1 - 0.043 13.4 0.2 0.082 12.5 0.1 1.4 1 0 0 1 1 1 0 Electron transfer flavoprotein FAD-binding domain MUG113 PF13455.1 KFX97584.1 - 5e-33 113.4 0.1 2.2e-32 111.3 0.1 2.1 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 KFX97584.1 - 3.8e-23 81.7 0.6 9.7e-23 80.4 0.0 2.0 2 1 1 3 3 3 1 T5orf172 domain Radical_SAM PF04055.16 KFX97585.1 - 3.2e-15 56.6 0.0 8e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 KFX97585.1 - 5.7e-12 45.4 0.0 1.5e-11 44.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family CoA_binding PF02629.14 KFX97586.1 - 1e-26 93.2 3.6 5e-26 91.0 0.8 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 KFX97586.1 - 2.3e-23 82.4 0.1 3.9e-23 81.7 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KFX97586.1 - 2.9e-09 36.6 0.0 5.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KFX97586.1 - 0.00014 21.9 0.8 0.00065 19.8 0.1 2.4 3 0 0 3 3 3 1 CoA binding domain CFEM PF05730.6 KFX97588.1 - 1.6e-14 53.4 14.1 2.6e-14 52.8 9.8 1.3 1 0 0 1 1 1 1 CFEM domain DpnD-PcfM PF14207.1 KFX97589.1 - 0.092 12.5 0.0 0.22 11.3 0.0 1.6 1 1 1 2 2 2 0 DpnD/PcfM-like protein PC_rep PF01851.17 KFX97590.1 - 7.8e-46 151.7 13.3 1.7e-08 34.2 0.0 9.0 8 0 0 8 8 8 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KFX97590.1 - 5.3e-19 68.3 0.4 2e-13 50.4 0.0 5.5 3 1 0 4 4 4 1 HEAT repeats HEAT PF02985.17 KFX97590.1 - 3.2e-09 36.0 0.3 0.95 9.7 0.0 6.0 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 KFX97590.1 - 1.1e-08 35.3 0.0 2.4e-05 24.6 0.0 4.9 4 0 0 4 4 4 1 HEAT-like repeat DUF1546 PF07571.8 KFX97590.1 - 0.087 12.9 0.1 15 5.7 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1546) mRNA_triPase PF02940.10 KFX97591.1 - 4.1e-56 190.1 0.1 6.3e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Glyco_hydro_20 PF00728.17 KFX97592.1 - 6.4e-99 331.4 0.9 5.4e-98 328.3 0.4 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Pkinase PF00069.20 KFX97592.1 - 1.4e-43 148.9 0.0 5.4e-43 147.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX97592.1 - 2.6e-31 108.6 0.0 3.8e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Glycohydro_20b2 PF14845.1 KFX97592.1 - 6.4e-21 75.3 0.0 1.8e-20 73.8 0.0 1.8 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KFX97592.1 - 0.00012 22.5 0.0 0.00027 21.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Kinase-like PF14531.1 KFX97592.1 - 0.015 14.2 0.0 0.038 12.9 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 KFX97592.1 - 0.075 12.0 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acyl_transf_3 PF01757.17 KFX97593.1 - 1e-28 100.2 27.4 1.3e-27 96.5 19.0 2.1 1 1 0 1 1 1 1 Acyltransferase family Cation_ATPase_C PF00689.16 KFX97593.1 - 1.6 8.1 8.3 6.6 6.2 0.1 3.1 2 2 0 2 2 2 0 Cation transporting ATPase, C-terminus SET PF00856.23 KFX97595.1 - 5.6e-10 39.7 0.0 1.5e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 SET domain Meleagrin PF08189.6 KFX97595.1 - 0.0033 16.8 0.4 0.0079 15.6 0.3 1.7 1 0 0 1 1 1 1 Meleagrin/Cygnin family TPR_11 PF13414.1 KFX97595.1 - 0.0043 16.6 0.0 0.009 15.6 0.0 1.4 1 0 0 1 1 1 1 TPR repeat Cep57_MT_bd PF06657.8 KFX97596.1 - 1.4e-27 95.3 0.1 1.4e-27 95.3 0.1 4.9 6 0 0 6 6 6 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 KFX97596.1 - 6e-09 35.7 6.9 6e-09 35.7 4.8 3.4 3 1 0 3 3 3 1 Centrosome localisation domain of PPC89 NmrA PF05368.8 KFX97596.1 - 7.3e-08 31.9 0.0 3.2e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family HALZ PF02183.13 KFX97596.1 - 1.2 8.9 15.7 0.1 12.3 1.9 3.8 4 0 0 4 4 4 0 Homeobox associated leucine zipper FtsL PF04999.8 KFX97596.1 - 10 5.9 13.0 1.1 9.0 1.0 3.0 3 0 0 3 3 3 0 Cell division protein FtsL SKG6 PF08693.5 KFX97597.1 - 1.5e-06 27.3 0.1 3.5e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1180 PF06679.7 KFX97597.1 - 0.005 16.7 1.7 0.01 15.6 0.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1180) HALZ PF02183.13 KFX97598.1 - 0.26 11.0 1.2 0.48 10.1 0.4 1.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Aconitase_C PF00694.14 KFX97600.1 - 6.6e-40 136.2 0.0 1.4e-39 135.1 0.0 1.5 2 0 0 2 2 2 1 Aconitase C-terminal domain YCII PF03795.9 KFX97601.1 - 8e-05 22.7 0.0 9.2e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain SUV3_C PF12513.3 KFX97604.1 - 1.8e-17 62.4 0.9 3.8e-17 61.4 0.1 2.0 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 KFX97604.1 - 1.4e-08 34.4 0.0 3.4e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Npa1 PF11707.3 KFX97605.1 - 8.5e-83 278.0 0.0 1.5e-82 277.2 0.0 1.4 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Longin PF13774.1 KFX97605.1 - 2e-22 78.5 0.0 4.4e-22 77.4 0.0 1.7 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KFX97605.1 - 5.2e-15 54.8 0.1 1.2e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Synaptobrevin Arm PF00514.18 KFX97605.1 - 0.00017 21.2 0.5 0.0015 18.2 0.0 3.0 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat Creb_binding PF09030.5 KFX97605.1 - 0.012 15.8 0.1 0.44 10.7 0.0 2.9 2 0 0 2 2 2 0 Creb binding S1 PF00575.18 KFX97605.1 - 0.097 12.7 0.1 11 6.1 0.1 2.5 2 0 0 2 2 2 0 S1 RNA binding domain Hist_deacetyl PF00850.14 KFX97606.1 - 3.3e-75 253.2 0.0 4.5e-75 252.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Ferritin_2 PF13668.1 KFX97607.1 - 2.9e-12 46.7 0.0 5.1e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain Mito_carr PF00153.22 KFX97608.1 - 3.1e-65 215.9 0.3 1.1e-22 79.5 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C65 PF10275.4 KFX97634.1 - 6e-12 45.4 0.0 7.3e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain DEAD PF00270.24 KFX97650.1 - 5.3e-45 152.9 1.2 1e-44 152.0 0.8 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX97650.1 - 1.1e-27 95.7 0.2 5.4e-27 93.4 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX97650.1 - 0.00076 19.3 0.0 0.0015 18.3 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KFX97650.1 - 0.0021 17.6 0.1 0.0072 15.9 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFX97650.1 - 0.011 15.8 0.1 0.032 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KFX97650.1 - 0.015 15.0 0.0 0.044 13.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain CMS1 PF14617.1 KFX97650.1 - 0.015 14.4 0.0 0.034 13.2 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit CobA_CobO_BtuR PF02572.10 KFX97650.1 - 0.077 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Flavi_DEAD PF07652.9 KFX97650.1 - 0.077 12.7 0.1 0.41 10.3 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain Fanconi_A PF03511.9 KFX97650.1 - 0.092 12.5 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein UvrD-helicase PF00580.16 KFX97650.1 - 0.098 11.9 0.1 0.14 11.4 0.1 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF605 PF04652.11 KFX97651.1 - 0.0037 16.7 17.8 0.0042 16.5 12.3 1.2 1 0 0 1 1 1 1 Vta1 like Mer2 PF09074.5 KFX97651.1 - 0.07 13.0 10.7 0.11 12.4 1.9 2.6 1 1 1 2 2 2 0 Mer2 Borrelia_REV PF03978.8 KFX97651.1 - 1.6 8.4 8.9 0.99 9.1 1.6 2.9 1 1 0 2 2 2 0 Borrelia burgdorferi REV protein DUF883 PF05957.8 KFX97651.1 - 2.3 8.6 17.6 1.1 9.6 0.7 4.2 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) LMP PF04778.7 KFX97651.1 - 3 7.5 9.5 4.8 6.9 4.0 2.9 1 1 1 2 2 2 0 LMP repeated region Prominin PF05478.6 KFX97651.1 - 7.7 3.9 8.4 2.2 5.6 0.6 2.1 1 1 1 2 2 2 0 Prominin DEAD PF00270.24 KFX97652.1 - 4.1e-09 36.1 0.0 4.1e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase TerY-C PF15616.1 KFX97652.1 - 0.041 13.8 0.1 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain FAM176 PF14851.1 KFX97653.1 - 0.002 17.7 0.0 0.0026 17.4 0.0 1.1 1 0 0 1 1 1 1 FAM176 family ADH_N PF08240.7 KFX97657.1 - 3.5e-28 97.5 0.1 7.7e-28 96.4 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX97657.1 - 1.3e-14 53.8 2.2 1.3e-14 53.8 1.6 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 KFX97657.1 - 9.3e-05 21.0 0.5 0.00014 20.4 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein 3HCDH_N PF02737.13 KFX97657.1 - 0.00028 20.6 0.5 0.00044 19.9 0.3 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KFX97657.1 - 0.00061 19.3 0.1 0.002 17.6 0.1 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 KFX97657.1 - 0.00067 18.6 3.1 0.0009 18.1 2.2 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFX97657.1 - 0.0018 17.2 1.9 0.0033 16.3 1.1 1.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFX97657.1 - 0.0019 18.2 1.7 0.0024 17.8 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.9 KFX97657.1 - 0.0026 17.1 0.1 0.0056 16.0 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 KFX97657.1 - 0.0049 16.0 0.0 0.0084 15.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 KFX97657.1 - 0.0072 16.1 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox_2 PF07992.9 KFX97657.1 - 0.017 15.0 1.1 0.28 11.0 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX97657.1 - 0.023 15.0 0.1 0.06 13.7 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KFX97657.1 - 0.028 13.8 0.1 0.048 13.1 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 KFX97657.1 - 0.038 13.7 0.1 0.06 13.0 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 KFX97657.1 - 0.27 10.0 3.0 0.35 9.6 2.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DFP PF04127.10 KFX97658.1 - 2.4e-13 50.1 0.0 1.9e-05 24.3 0.0 3.2 2 1 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein ResIII PF04851.10 KFX97662.1 - 2.3e-21 76.4 0.0 4e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFX97662.1 - 2.3e-20 72.7 0.0 1.3e-19 70.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX97662.1 - 2.3e-18 65.8 0.2 6.3e-18 64.4 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KFX97662.1 - 0.00027 21.0 0.0 0.0012 19.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KFX97662.1 - 0.35 10.2 1.7 5.4 6.3 0.0 2.7 2 1 0 3 3 3 0 AAA-like domain E1-E2_ATPase PF00122.15 KFX97663.1 - 2.6e-62 209.8 4.1 5.7e-62 208.7 2.8 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFX97663.1 - 1.3e-36 125.8 2.9 1.3e-36 125.8 2.0 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFX97663.1 - 7e-29 101.7 0.0 3.7e-27 96.1 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFX97663.1 - 8.8e-23 80.0 0.0 2.5e-22 78.6 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KFX97663.1 - 3.7e-12 45.5 0.0 1.3e-11 43.8 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFX97663.1 - 2.2e-11 44.2 0.0 6.2e-11 42.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFX97663.1 - 1.1e-05 25.1 0.4 0.0025 17.4 0.3 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase BAH PF01426.13 KFX97664.1 - 2.5e-07 30.4 0.0 5.2e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 BAH domain DUF4101 PF13355.1 KFX97664.1 - 0.01 16.1 0.3 0.037 14.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4101) PHD PF00628.24 KFX97664.1 - 0.99 9.1 10.5 0.2 11.3 3.4 2.4 2 0 0 2 2 2 0 PHD-finger ATP-synt PF00231.14 KFX97665.1 - 6.3e-70 235.8 8.4 7.3e-70 235.5 5.9 1.0 1 0 0 1 1 1 1 ATP synthase DUF4325 PF14213.1 KFX97665.1 - 0.071 12.7 0.1 0.18 11.4 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4325) NT5C PF06941.7 KFX97665.1 - 0.072 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) ChiC PF06483.6 KFX97665.1 - 0.13 11.9 1.4 0.47 10.1 0.1 2.2 2 0 0 2 2 2 0 Chitinase C Topoisom_I_N PF02919.10 KFX97666.1 - 6.1e-96 319.8 1.1 6.1e-96 319.8 0.8 3.9 4 1 1 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 KFX97666.1 - 2.2e-85 285.5 4.3 2.2e-85 285.5 3.0 2.6 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 KFX97666.1 - 2.5e-31 107.1 0.2 9e-31 105.3 0.2 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 KFX97666.1 - 0.032 13.3 0.1 0.073 12.2 0.1 1.5 1 0 0 1 1 1 0 RolB/RolC glucosidase family Ribosomal_S15 PF00312.17 KFX97666.1 - 2.3 8.0 7.5 0.37 10.5 0.9 2.9 2 0 0 2 2 2 0 Ribosomal protein S15 Epimerase PF01370.16 KFX97667.1 - 1.3e-21 77.1 0.0 2.2e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KFX97667.1 - 6e-10 38.4 0.0 9.4e-10 37.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KFX97667.1 - 3e-08 33.8 0.1 1.1e-07 32.0 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KFX97667.1 - 9.1e-07 28.9 0.0 2.3e-06 27.6 0.0 1.8 2 1 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KFX97667.1 - 8.2e-06 24.7 0.0 1.2e-05 24.1 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KFX97667.1 - 0.0027 17.3 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 KFX97667.1 - 0.0098 14.8 0.0 0.017 14.0 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Ldh_1_N PF00056.18 KFX97667.1 - 0.015 15.1 0.0 0.066 13.0 0.0 2.0 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 KFX97667.1 - 0.068 12.1 0.0 0.098 11.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase UCH PF00443.24 KFX97669.1 - 1.6e-48 165.1 0.0 2.4e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFX97669.1 - 2.3e-19 69.9 0.0 9.1e-19 67.9 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4_2 PF13923.1 KFX97670.1 - 2.5e-07 30.6 9.7 4.2e-07 29.8 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX97670.1 - 3.8e-07 29.6 8.7 6.5e-07 28.9 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFX97670.1 - 3.7e-06 26.4 6.0 6.3e-06 25.7 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFX97670.1 - 5e-06 26.2 8.9 8.5e-06 25.5 6.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KFX97670.1 - 1.3e-05 25.0 8.0 2.5e-05 24.0 5.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KFX97670.1 - 6.2e-05 22.6 6.6 0.00012 21.7 4.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFX97670.1 - 0.1 12.3 6.1 0.23 11.2 4.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger CbiC PF02570.10 KFX97670.1 - 0.13 11.6 0.1 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Precorrin-8X methylmutase Rrn6 PF10214.4 KFX97670.1 - 5.1 5.0 12.4 7.8 4.4 8.6 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor 4HBT_2 PF13279.1 KFX97671.1 - 2.8e-09 37.4 0.0 4.5e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily CMAS PF02353.15 KFX97672.1 - 2e-63 214.0 0.2 2.5e-63 213.7 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KFX97672.1 - 2.1e-11 43.7 0.0 3.6e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX97672.1 - 1.4e-07 31.9 0.0 2.9e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX97672.1 - 9.1e-05 21.8 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KFX97672.1 - 0.00012 22.1 0.0 0.0006 19.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX97672.1 - 0.00016 22.2 0.0 0.00034 21.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX97672.1 - 0.00019 21.8 0.0 0.00035 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX97672.1 - 0.00079 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 KFX97672.1 - 0.0021 17.4 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.1 KFX97672.1 - 0.0023 18.2 0.0 0.0047 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KFX97672.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 KFX97672.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain 2OG-FeII_Oxy PF03171.15 KFX97673.1 - 2.7e-21 75.6 0.0 6.1e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KFX97673.1 - 2.9e-08 34.2 0.0 4.3e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Dioxygenase_C PF00775.16 KFX97675.1 - 1.6e-10 40.5 0.1 3.1e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase MFS_1 PF07690.11 KFX97676.1 - 5.4e-45 153.6 45.0 2e-44 151.7 27.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX97676.1 - 3.6e-07 29.1 14.2 3.6e-07 29.1 9.9 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter CFEM PF05730.6 KFX97677.1 - 8.7e-11 41.4 14.2 1.4e-10 40.8 9.8 1.4 1 0 0 1 1 1 1 CFEM domain DUF566 PF04484.7 KFX97677.1 - 2.5 7.5 6.7 3.1 7.2 4.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) p450 PF00067.17 KFX97679.1 - 4.7e-51 173.7 0.0 6.8e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cyclase PF04199.8 KFX97680.1 - 1.1e-11 44.6 0.7 2.1e-11 43.7 0.5 1.5 1 1 0 1 1 1 1 Putative cyclase CAF-1_p150 PF11600.3 KFX97684.1 - 0.21 10.9 2.6 0.38 10.0 1.8 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Methyltransf_31 PF13847.1 KFX97685.1 - 4e-27 94.6 0.0 6.9e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX97685.1 - 3.1e-17 62.8 0.0 6.7e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX97685.1 - 4.1e-14 52.2 0.0 6.3e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KFX97685.1 - 2.6e-13 50.5 0.0 4.9e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX97685.1 - 9e-12 44.9 0.0 1.6e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX97685.1 - 1.3e-11 44.6 0.0 2.6e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX97685.1 - 5.9e-11 42.4 0.0 1.1e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX97685.1 - 1.6e-10 41.2 0.0 2.7e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFX97685.1 - 7.5e-08 31.8 0.3 1.6e-07 30.7 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 KFX97685.1 - 5.6e-07 29.3 0.0 8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 KFX97685.1 - 5.2e-05 22.6 0.0 8.7e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.9 KFX97685.1 - 7.8e-05 22.1 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 KFX97685.1 - 0.0004 19.5 0.0 0.00061 18.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.13 KFX97685.1 - 0.0082 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 KFX97685.1 - 0.019 14.0 0.0 0.037 13.0 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_3 PF01596.12 KFX97685.1 - 0.14 11.2 0.0 0.27 10.2 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase Fe_hyd_lg_C PF02906.9 KFX97685.1 - 0.16 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Methyltransf_9 PF08003.6 KFX97685.1 - 0.16 10.6 0.0 9.6 4.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Zn_clus PF00172.13 KFX97686.1 - 7.7e-05 22.5 13.7 0.00013 21.8 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX97686.1 - 0.0094 14.8 0.0 0.016 14.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 KFX97688.1 - 3.2e-50 170.7 4.3 3.2e-50 170.7 3.0 1.9 2 0 0 2 2 2 1 RTA1 like protein DUF2975 PF11188.3 KFX97688.1 - 3.4 7.3 15.8 0.27 10.9 2.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) AstE_AspA PF04952.9 KFX97689.1 - 2e-21 76.1 0.1 1.7e-13 50.1 0.0 2.5 2 1 1 3 3 3 2 Succinylglutamate desuccinylase / Aspartoacylase family MFS_1 PF07690.11 KFX97690.1 - 5.2e-35 120.7 31.7 7.7e-35 120.2 21.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 KFX97690.1 - 0.0013 18.7 6.7 0.0042 17.0 0.5 3.9 3 1 1 4 4 4 1 Protein of unknown function (DUF1228) DUF872 PF05915.7 KFX97690.1 - 1 9.2 4.4 14 5.5 0.1 3.5 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Fungal_trans_2 PF11951.3 KFX97691.1 - 6.3e-05 21.7 0.2 0.007 15.0 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Methyltransf_11 PF08241.7 KFX97692.1 - 1.6e-20 73.3 0.1 2.7e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX97692.1 - 1.7e-16 60.1 0.0 2.2e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX97692.1 - 2.9e-16 59.6 0.0 5.1e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX97692.1 - 7.5e-13 49.0 0.0 1.3e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX97692.1 - 2.2e-12 47.0 0.1 4.7e-12 45.9 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KFX97692.1 - 2.9e-12 46.2 0.0 4.2e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 KFX97692.1 - 7.8e-12 45.5 0.0 1.3e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX97692.1 - 5.9e-11 42.6 0.1 1.1e-10 41.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX97692.1 - 1e-09 37.8 0.0 2.7e-08 33.2 0.0 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 KFX97692.1 - 6.9e-08 32.2 0.0 1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 KFX97692.1 - 9.6e-08 31.5 0.0 1.4e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 KFX97692.1 - 9.7e-07 28.5 0.0 1.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_9 PF08003.6 KFX97692.1 - 1.2e-05 24.2 0.0 1.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.1 KFX97692.1 - 3.9e-05 23.3 0.0 5.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 KFX97692.1 - 6.4e-05 22.5 0.0 8.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MetW PF07021.7 KFX97692.1 - 8.5e-05 22.0 0.0 0.00013 21.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.8 KFX97692.1 - 8.7e-05 21.7 0.0 0.00013 21.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DUF633 PF04816.7 KFX97692.1 - 0.0002 20.7 0.1 0.00029 20.2 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF633) TPMT PF05724.6 KFX97692.1 - 0.00025 20.5 0.0 0.0004 19.8 0.0 1.4 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) TehB PF03848.9 KFX97692.1 - 0.00046 19.3 0.0 0.00069 18.8 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB GCD14 PF08704.5 KFX97692.1 - 0.0011 18.5 0.1 0.0024 17.4 0.0 1.5 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit NodS PF05401.6 KFX97692.1 - 0.0064 15.9 0.0 0.0097 15.3 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_24 PF13578.1 KFX97692.1 - 0.008 16.9 0.1 0.015 16.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 KFX97692.1 - 0.0085 15.1 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.12 KFX97692.1 - 0.046 12.7 0.0 0.76 8.7 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_8 PF05148.10 KFX97692.1 - 0.077 12.6 0.0 0.78 9.3 0.0 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase Met_10 PF02475.11 KFX97692.1 - 0.092 12.3 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Met-10+ like-protein tRNA_U5-meth_tr PF05958.6 KFX97692.1 - 0.13 10.9 0.0 0.26 9.9 0.0 1.4 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase SYF2 PF08231.7 KFX97698.1 - 1.1e-52 178.2 13.6 1.1e-52 178.2 9.5 2.0 2 1 0 2 2 2 1 SYF2 splicing factor ARD PF03079.9 KFX97698.1 - 0.012 15.5 1.0 0.012 15.5 0.7 2.9 2 1 0 3 3 3 0 ARD/ARD' family NAD_binding_10 PF13460.1 KFX97699.1 - 2e-13 50.7 0.0 3.3e-12 46.7 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX97699.1 - 1e-07 31.6 0.0 2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFX97699.1 - 0.00012 20.8 0.0 0.00024 19.9 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KFX97699.1 - 0.0025 16.7 0.0 0.083 11.8 0.0 2.5 3 1 0 3 3 3 1 Male sterility protein adh_short PF00106.20 KFX97699.1 - 0.012 15.5 0.0 0.036 13.9 0.0 1.8 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 KFX97699.1 - 0.073 11.9 0.0 0.72 8.6 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain YEATS PF03366.11 KFX97700.1 - 6.3e-30 102.7 0.1 1.1e-29 101.9 0.1 1.4 1 0 0 1 1 1 1 YEATS family DUF4407 PF14362.1 KFX97701.1 - 4.4 6.1 11.7 4.2 6.2 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DEAD PF00270.24 KFX97702.1 - 5.1e-34 117.1 0.0 8e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX97702.1 - 4.2e-18 64.9 0.0 1.5e-16 59.9 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX97702.1 - 0.0025 17.6 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Methyltransf_31 PF13847.1 KFX97703.1 - 5.9e-29 100.6 0.0 8.4e-29 100.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX97703.1 - 1.2e-26 92.9 0.0 2e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX97703.1 - 5e-22 78.3 0.0 7.7e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX97703.1 - 2.2e-18 66.2 0.0 3.8e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KFX97703.1 - 2.5e-18 66.3 0.0 4.3e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX97703.1 - 5.5e-15 55.5 0.0 9.2e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX97703.1 - 6.5e-15 55.6 0.1 1.4e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KFX97703.1 - 7.9e-09 35.1 0.0 1.1e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 KFX97703.1 - 8.1e-09 35.5 0.4 1.8e-08 34.3 0.3 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX97703.1 - 5.3e-08 32.4 0.0 7.8e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KFX97703.1 - 1.9e-06 27.5 0.0 2.6e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 KFX97703.1 - 0.00015 20.9 0.0 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.11 KFX97703.1 - 0.00019 19.9 0.0 0.00025 19.5 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.8 KFX97703.1 - 0.00029 20.0 0.0 0.0004 19.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 KFX97703.1 - 0.00029 19.9 0.0 0.00042 19.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.6 KFX97703.1 - 0.0028 16.4 0.0 0.0056 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) FtsJ PF01728.14 KFX97703.1 - 0.0059 16.6 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase GCD14 PF08704.5 KFX97703.1 - 0.0089 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit NodS PF05401.6 KFX97703.1 - 0.014 14.7 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) FmrO PF07091.6 KFX97703.1 - 0.018 14.0 0.0 0.025 13.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_2 PF00891.13 KFX97703.1 - 0.021 14.0 0.2 0.029 13.5 0.1 1.2 1 0 0 1 1 1 0 O-methyltransferase DREV PF05219.7 KFX97703.1 - 0.03 13.1 0.0 0.047 12.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_32 PF13679.1 KFX97703.1 - 0.075 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 KFX97703.1 - 0.097 11.6 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase p450 PF00067.17 KFX97704.1 - 1.8e-61 208.0 0.0 2.7e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CBFD_NFYB_HMF PF00808.18 KFX97704.1 - 9.7e-13 47.9 3.1 2.9e-12 46.4 1.0 2.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFX97704.1 - 1.1e-06 28.6 0.7 2.7e-06 27.4 0.5 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PilJ PF13675.1 KFX97705.1 - 0.0027 18.0 5.2 1.9 8.8 0.6 3.2 2 1 1 3 3 3 2 Type IV pili methyl-accepting chemotaxis transducer N-term WXG100 PF06013.7 KFX97705.1 - 0.0094 15.9 4.7 0.64 10.0 0.0 4.0 4 1 0 4 4 4 1 Proteins of 100 residues with WXG DUF3452 PF11934.3 KFX97705.1 - 0.034 13.4 1.2 3.8 6.8 0.2 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF3452) HALZ PF02183.13 KFX97705.1 - 0.034 13.8 4.1 0.034 13.8 2.9 3.3 3 0 0 3 3 3 0 Homeobox associated leucine zipper TBPIP PF07106.8 KFX97705.1 - 0.099 12.1 10.8 1.9 7.9 0.0 3.1 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Bacillus_HBL PF05791.6 KFX97705.1 - 0.17 11.2 7.7 0.98 8.7 0.6 2.8 3 1 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF2031 PF09592.5 KFX97705.1 - 0.21 10.7 6.7 2.4 7.2 0.3 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF2031) Spc24 PF08286.6 KFX97705.1 - 0.41 10.3 6.7 1.1 9.0 0.9 3.1 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 DASH_Dad2 PF08654.5 KFX97705.1 - 0.41 10.6 8.9 6.6 6.7 0.2 3.3 2 1 1 3 3 3 0 DASH complex subunit Dad2 CENP-F_leu_zip PF10473.4 KFX97705.1 - 0.45 10.3 19.5 1.1 9.0 7.7 3.1 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GldM_N PF12081.3 KFX97705.1 - 0.75 9.2 7.4 0.71 9.3 0.8 3.0 2 1 0 3 3 3 0 GldM N-terminal domain BLOC1_2 PF10046.4 KFX97705.1 - 0.76 9.9 8.2 0.22 11.6 0.6 3.2 2 2 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin-6_N PF09177.6 KFX97705.1 - 0.86 10.0 10.1 5 7.5 1.2 3.4 3 1 0 3 3 3 0 Syntaxin 6, N-terminal PV-1 PF06637.6 KFX97705.1 - 1.3 7.5 9.5 0.33 9.4 4.1 1.7 1 1 1 2 2 2 0 PV-1 protein (PLVAP) bZIP_1 PF00170.16 KFX97705.1 - 1.4 8.8 7.4 0.27 11.2 1.3 2.6 3 0 0 3 3 2 0 bZIP transcription factor EMP24_GP25L PF01105.19 KFX97705.1 - 1.8 8.2 9.9 0.48 10.1 0.1 3.1 1 1 2 3 3 3 0 emp24/gp25L/p24 family/GOLD DUF724 PF05266.9 KFX97705.1 - 1.9 8.0 11.9 2.8 7.4 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF724) AAA_23 PF13476.1 KFX97705.1 - 1.9 8.7 13.4 2.9 8.1 9.2 1.4 1 1 0 1 1 1 0 AAA domain DUF972 PF06156.8 KFX97705.1 - 2 8.8 10.6 0.44 10.9 1.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 KFX97705.1 - 2 8.1 8.7 1.9 8.2 0.6 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) H-kinase_dim PF02895.9 KFX97705.1 - 2.9 8.2 10.4 29 5.1 4.2 3.4 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain DivIVA PF05103.8 KFX97705.1 - 3.3 7.7 12.3 1.4 8.9 5.0 2.8 2 2 1 3 3 3 0 DivIVA protein IncA PF04156.9 KFX97705.1 - 4 6.9 20.8 1.5 8.4 8.0 2.9 1 1 1 3 3 3 0 IncA protein Prefoldin PF02996.12 KFX97705.1 - 5.9 6.5 14.3 2.6 7.7 2.8 4.1 3 2 0 4 4 4 0 Prefoldin subunit Ribosomal_L29 PF00831.18 KFX97705.1 - 8.1 6.2 8.2 2.3 7.9 2.7 2.4 2 0 0 2 2 1 0 Ribosomal L29 protein CTP_synth_N PF06418.9 KFX97706.1 - 5e-120 399.7 0.3 6.7e-120 399.3 0.2 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KFX97706.1 - 2.7e-54 183.5 0.0 4.6e-54 182.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KFX97706.1 - 3.4e-08 33.2 0.0 9.1e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 KFX97706.1 - 0.0044 16.4 0.0 0.011 15.1 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Lyase_1 PF00206.15 KFX97707.1 - 1.7e-20 73.4 0.1 2.9e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 KFX97707.1 - 2.1e-11 43.6 0.0 7.7e-11 41.8 0.0 2.1 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF3328 PF11807.3 KFX97708.1 - 1.6e-31 109.6 0.5 2.1e-31 109.3 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Reprolysin_5 PF13688.1 KFX97712.1 - 0.0046 16.8 0.2 0.0066 16.3 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFX97712.1 - 0.024 15.1 0.6 0.069 13.6 0.4 1.9 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like adh_short PF00106.20 KFX97713.1 - 6.2e-22 78.2 0.0 9.4e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX97713.1 - 1.5e-07 31.2 0.0 2.4e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFX97713.1 - 0.00035 20.4 0.0 0.00053 19.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ATP-grasp_5 PF13549.1 KFX97713.1 - 0.048 12.8 0.1 0.085 12.0 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain RtcR PF06956.6 KFX97713.1 - 0.072 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase MFS_1 PF07690.11 KFX97714.1 - 1.8e-23 82.8 10.7 2.1e-23 82.6 7.4 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Gln-synt_N PF03951.14 KFX97714.1 - 0.019 14.5 0.0 0.18 11.4 0.0 2.4 3 0 0 3 3 3 0 Glutamine synthetase, beta-Grasp domain DUF4231 PF14015.1 KFX97714.1 - 0.33 10.9 1.7 0.97 9.4 1.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) CDC45 PF02724.9 KFX97715.1 - 2.2e-219 729.6 0.0 4.7e-219 728.5 0.0 1.9 1 1 0 1 1 1 1 CDC45-like protein Sugar_tr PF00083.19 KFX97718.1 - 6.9e-104 347.9 27.2 8.6e-104 347.6 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX97718.1 - 1.4e-22 79.9 31.9 4.7e-15 55.1 5.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KFX97718.1 - 0.52 8.2 14.1 0.58 8.1 1.8 3.6 2 2 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family Crystall PF00030.14 KFX97720.1 - 4.6e-05 23.2 0.1 0.00013 21.7 0.0 1.7 2 0 0 2 2 2 1 Beta/Gamma crystallin Crystall_3 PF08964.5 KFX97720.1 - 0.0044 16.7 0.1 0.013 15.1 0.0 1.9 2 0 0 2 2 2 1 Beta/Gamma crystallin Crystall PF00030.14 KFX97721.1 - 0.056 13.3 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 Beta/Gamma crystallin DUF1682 PF07946.9 KFX97722.1 - 7.4e-95 317.4 0.0 8.5e-95 317.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Methyltransf_23 PF13489.1 KFX97723.1 - 5.4e-12 45.7 0.0 8.4e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX97723.1 - 2.5e-06 28.0 0.1 8.3e-05 23.1 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX97723.1 - 5.8e-05 22.7 0.0 0.0014 18.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX97723.1 - 0.00038 20.8 0.0 0.0059 17.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX97723.1 - 0.00054 20.3 0.0 0.001 19.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KFX97723.1 - 0.042 13.8 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 KFX97723.1 - 0.066 13.2 0.0 0.18 11.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KFX97723.1 - 0.087 12.1 0.0 0.26 10.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain FAD_binding_3 PF01494.14 KFX97724.1 - 3e-19 69.3 2.0 6.8e-13 48.3 0.2 2.3 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KFX97724.1 - 1.5e-07 30.6 0.0 0.012 14.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 KFX97724.1 - 6.3e-05 22.2 0.2 0.00074 18.7 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KFX97724.1 - 0.00018 21.4 0.1 0.00057 19.8 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFX97724.1 - 0.00054 20.3 0.3 0.44 10.9 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFX97724.1 - 0.00059 18.4 0.1 0.43 8.9 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.7 KFX97724.1 - 0.0024 16.8 0.1 0.48 9.2 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 KFX97724.1 - 0.003 16.4 1.5 0.0085 14.9 0.3 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 KFX97724.1 - 0.018 15.0 0.0 0.067 13.2 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX97724.1 - 0.019 14.7 0.0 2 8.1 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KFX97724.1 - 0.024 14.4 0.0 0.073 12.9 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF3748 PF12566.3 KFX97725.1 - 0.11 12.4 0.1 0.51 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3748) Epimerase PF01370.16 KFX97726.1 - 6.2e-15 55.2 0.0 1.2e-14 54.3 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFX97726.1 - 9.8e-12 44.3 0.0 4.5e-10 38.8 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KFX97726.1 - 5.8e-10 39.4 0.1 3.7e-09 36.8 0.1 2.3 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFX97726.1 - 3e-07 29.4 0.0 4.4e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KFX97726.1 - 0.0037 17.1 0.0 0.007 16.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX97726.1 - 0.083 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 KR domain ADK PF00406.17 KFX97727.1 - 9.4e-59 197.6 0.1 1.2e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KFX97727.1 - 1.8e-14 53.1 0.0 5.1e-14 51.6 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.1 KFX97727.1 - 0.00032 21.4 0.0 0.00052 20.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFX97727.1 - 0.00065 19.5 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFX97727.1 - 0.0022 18.3 0.0 0.0038 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFX97727.1 - 0.015 14.4 0.0 0.023 13.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.16 KFX97727.1 - 0.069 12.3 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CCDC92 PF14916.1 KFX97727.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain of unknown function MitMem_reg PF13012.1 KFX97728.1 - 1.1e-38 131.8 0.1 2.6e-38 130.6 0.1 1.7 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Cyclin PF08613.6 KFX97728.1 - 4.5e-28 98.5 0.0 1e-27 97.3 0.0 1.6 1 0 0 1 1 1 1 Cyclin JAB PF01398.16 KFX97728.1 - 5.9e-27 93.6 0.0 1.4e-26 92.4 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Cyclin_N PF00134.18 KFX97728.1 - 0.00033 20.2 0.0 0.00066 19.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF4407 PF14362.1 KFX97728.1 - 0.68 8.8 3.5 1.2 8.0 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lipase_3 PF01764.20 KFX97729.1 - 3.7e-38 130.3 0.0 7.4e-38 129.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 KFX97729.1 - 6.1e-07 29.1 0.3 1.5e-06 27.8 0.2 1.6 1 0 0 1 1 1 1 Lipase 3 N-terminal region DUF2974 PF11187.3 KFX97729.1 - 6.2e-05 22.4 0.6 0.00026 20.4 0.4 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 KFX97729.1 - 0.00021 21.0 0.1 0.00035 20.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 KFX97729.1 - 0.00034 20.1 0.2 0.00093 18.7 0.2 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase Abhydrolase_6 PF12697.2 KFX97729.1 - 0.00042 20.2 0.1 0.0006 19.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 KFX97729.1 - 0.0012 18.5 0.3 0.0036 17.0 0.2 1.8 1 1 0 1 1 1 1 Cutinase PGAP1 PF07819.8 KFX97729.1 - 0.0028 17.2 0.0 0.005 16.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KFX97729.1 - 0.0076 15.5 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Thioesterase PF00975.15 KFX97729.1 - 0.064 13.4 0.1 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain MOZ_SAS PF01853.13 KFX97754.1 - 3.1e-60 202.6 0.0 5.5e-60 201.8 0.0 1.3 1 0 0 1 1 1 1 MOZ/SAS family CorA PF01544.13 KFX97754.1 - 0.049 12.6 0.0 0.084 11.8 0.0 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein adh_short PF00106.20 KFX97755.1 - 1e-17 64.5 0.1 1.7e-17 63.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX97755.1 - 2.6e-05 23.9 0.1 4.5e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KFX97755.1 - 0.29 10.9 3.2 0.28 10.9 0.7 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AAA_16 PF13191.1 KFX97756.1 - 3.8e-06 27.0 0.1 0.00016 21.7 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 KFX97756.1 - 6.1e-05 22.8 0.1 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 KFX97756.1 - 0.0027 17.8 0.1 0.0094 16.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KFX97756.1 - 0.0056 16.1 0.0 0.018 14.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 KFX97756.1 - 0.0078 15.7 0.0 0.16 11.4 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.1 KFX97756.1 - 0.013 15.0 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 KFX97756.1 - 0.16 12.4 0.2 1.3 9.5 0.2 2.4 1 1 0 1 1 1 0 Miro-like protein Myb_DNA-bind_6 PF13921.1 KFX97757.1 - 6.5e-19 67.7 8.1 9e-14 51.3 0.7 3.4 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KFX97757.1 - 2.4e-17 62.7 6.6 3.2e-09 36.6 0.7 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KFX97757.1 - 0.019 15.0 8.1 0.068 13.3 0.8 3.2 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 KFX97757.1 - 0.046 13.9 11.1 0.44 10.7 0.2 3.6 3 2 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Fer4 PF00037.22 KFX97758.1 - 5.8e-14 51.0 16.5 3.2e-08 32.8 2.5 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 KFX97758.1 - 1.9e-12 47.3 10.5 2.9e-12 46.7 7.2 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 KFX97758.1 - 2.1e-10 40.6 8.4 3.8e-10 39.8 5.9 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 KFX97758.1 - 4.3e-10 39.2 22.5 3.5e-08 33.1 8.7 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 KFX97758.1 - 1.2e-09 38.7 8.2 9.6e-05 23.0 0.5 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_8 PF13183.1 KFX97758.1 - 7.4e-09 35.5 19.3 6.1e-06 26.1 7.6 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_21 PF14697.1 KFX97758.1 - 3.9e-08 33.0 10.9 0.0002 21.1 1.5 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 KFX97758.1 - 5.3e-08 32.3 14.7 0.00027 20.6 1.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 KFX97758.1 - 1e-07 31.4 17.1 0.00076 19.2 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 KFX97758.1 - 2e-06 27.6 12.7 0.00036 20.6 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 KFX97758.1 - 2.2e-06 27.9 10.0 0.00028 21.1 7.4 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 KFX97758.1 - 2.9e-05 24.3 10.3 0.014 15.8 0.8 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 KFX97758.1 - 0.0051 17.1 16.1 0.19 12.1 3.2 2.9 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 KFX97758.1 - 0.011 16.2 14.4 0.18 12.4 1.2 2.9 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 KFX97758.1 - 0.03 14.8 16.9 0.1 13.2 2.4 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 KFX97758.1 - 0.051 13.6 5.0 0.12 12.5 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain MARVEL PF01284.18 KFX97765.1 - 0.0071 16.1 4.7 0.032 14.0 3.2 1.8 1 1 0 1 1 1 1 Membrane-associating domain Cytochrom_C_asm PF01578.15 KFX97765.1 - 0.015 14.8 1.3 0.025 14.1 0.1 1.8 2 0 0 2 2 2 0 Cytochrome C assembly protein DUF1404 PF07185.6 KFX97765.1 - 1.9 8.0 6.5 30 4.1 4.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1404) Pkinase PF00069.20 KFX97766.1 - 3.3e-26 92.0 0.0 4.6e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX97766.1 - 5.8e-07 28.8 0.0 1.4e-06 27.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KFX97766.1 - 0.011 15.4 0.1 0.2 11.3 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KFX97766.1 - 0.028 13.4 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFX97766.1 - 0.043 12.7 0.0 0.068 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 KFX97766.1 - 0.084 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 KFX97766.1 - 0.21 10.3 0.0 0.29 9.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DASH_Ask1 PF08655.5 KFX97768.1 - 2.2e-33 113.8 0.0 3.4e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 DAP3 PF10236.4 KFX97791.1 - 4.3e-50 170.4 0.0 4.8e-50 170.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 RhoGAP PF00620.22 KFX97792.1 - 2.6e-29 101.8 0.0 4.5e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain MutS_V PF00488.16 KFX97793.1 - 5.8e-85 284.4 0.0 8.9e-85 283.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFX97793.1 - 4.1e-40 137.7 0.7 7.2e-40 136.9 0.5 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KFX97793.1 - 3.1e-27 94.8 0.0 8.1e-27 93.5 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KFX97793.1 - 4.7e-08 33.1 0.1 1.7e-07 31.3 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KFX97793.1 - 4.1e-06 26.8 0.0 1.5e-05 25.0 0.0 2.1 1 0 0 1 1 1 1 MutS family domain IV DUF2014 PF09427.5 KFX97794.1 - 0.023 13.8 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2014) Prenyltrans PF00432.16 KFX97796.1 - 7e-57 188.6 14.3 1.3e-11 43.7 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KFX97796.1 - 7.1e-28 97.2 0.0 1.1e-14 54.7 0.0 3.9 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KFX97796.1 - 5.8e-09 35.9 0.0 0.0004 20.3 0.0 2.8 1 1 1 2 2 2 2 Prenyltransferase-like Pyr_redox_3 PF13738.1 KFX97797.1 - 7.5e-15 55.5 0.0 1.3e-13 51.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFX97797.1 - 2.6e-13 49.0 0.1 4.6e-08 31.7 0.0 3.5 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KFX97797.1 - 1.5e-09 38.0 0.0 3.2e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX97797.1 - 2.2e-08 34.0 0.0 5.5e-07 29.4 0.0 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KFX97797.1 - 1e-06 28.6 0.0 6e-06 26.1 0.0 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KFX97797.1 - 2.6e-06 26.6 0.0 1.3e-05 24.2 0.0 2.2 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KFX97797.1 - 7.4e-05 23.0 0.0 5.8 7.4 0.0 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFX97797.1 - 0.019 14.0 0.1 0.035 13.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 KFX97797.1 - 0.023 13.7 0.0 0.056 12.5 0.0 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KFX97797.1 - 0.14 10.6 0.2 0.64 8.4 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein DUF1903 PF08991.5 KFX97799.1 - 2.5e-05 24.3 0.9 2.9e-05 24.1 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 KFX97799.1 - 0.0001 22.0 4.2 0.00039 20.2 2.9 1.9 1 1 1 2 2 2 1 CHCH domain YqzE PF14038.1 KFX97799.1 - 0.02 14.6 1.2 0.87 9.3 0.2 2.2 2 0 0 2 2 2 0 YqzE-like protein Cmc1 PF08583.5 KFX97799.1 - 0.025 14.3 3.4 0.55 10.0 0.4 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 KFX97799.1 - 0.068 13.0 3.6 0.26 11.1 2.5 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Pet191_N PF10203.4 KFX97799.1 - 0.2 11.6 3.0 0.45 10.6 2.1 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CBM_1 PF00734.13 KFX97800.1 - 1.8e-13 49.9 14.0 1.8e-13 49.9 9.7 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain AXE1 PF05448.7 KFX97800.1 - 0.18 10.2 0.1 0.34 9.3 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Methyltransf_15 PF09445.5 KFX97801.1 - 2.5e-40 137.6 0.0 5.9e-40 136.5 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Lipase_GDSL_2 PF13472.1 KFX97801.1 - 1.7e-15 57.6 1.5 1.4e-14 54.6 0.6 2.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFX97801.1 - 4.1e-13 49.7 2.5 6.6e-13 49.0 0.5 2.3 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Met_10 PF02475.11 KFX97801.1 - 3.5e-08 33.3 0.0 8.2e-08 32.0 0.0 1.6 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 KFX97801.1 - 4.7e-08 33.6 0.4 3.8e-07 30.6 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.13 KFX97801.1 - 1.1e-06 28.3 0.0 3.1e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 KFX97801.1 - 3.3e-05 23.3 0.2 0.00028 20.3 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 KFX97801.1 - 0.00011 22.1 0.0 0.00036 20.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX97801.1 - 0.0017 17.9 0.3 0.0077 15.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain DNA_methylase PF00145.12 KFX97801.1 - 0.0092 15.1 0.2 0.0092 15.1 0.1 2.3 2 1 0 2 2 1 1 C-5 cytosine-specific DNA methylase MTS PF05175.9 KFX97801.1 - 0.055 12.8 0.3 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain V_ATPase_I PF01496.14 KFX97801.1 - 0.57 7.9 10.3 0.86 7.3 7.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 KFX97801.1 - 9.8 5.7 9.5 4.2 6.9 4.7 1.7 2 0 0 2 2 2 0 IncA protein GRASP55_65 PF04495.9 KFX97802.1 - 4.3e-46 156.3 0.0 1.1e-44 151.7 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain Dopey_N PF04118.9 KFX97803.1 - 7.4e-117 389.5 0.0 2.5e-115 384.5 0.0 2.9 3 0 0 3 3 3 1 Dopey, N-terminal Mon1 PF03164.9 KFX97804.1 - 7.6e-115 383.8 0.0 9.4e-115 383.5 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Meleagrin PF08189.6 KFX97804.1 - 0.26 10.7 0.8 0.46 9.9 0.5 1.3 1 0 0 1 1 1 0 Meleagrin/Cygnin family PHO4 PF01384.15 KFX97805.1 - 3.5e-113 377.5 22.2 4.3e-113 377.2 15.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family DNA_binding_1 PF01035.15 KFX97809.1 - 2.6e-22 78.3 0.0 4e-22 77.7 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain CRAL_TRIO PF00650.15 KFX97810.1 - 1.3e-11 44.2 0.0 1.9e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFX97810.1 - 0.00016 21.7 0.0 0.0004 20.4 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Herpes_BLLF1 PF05109.8 KFX97810.1 - 0.99 7.2 8.4 1.3 6.9 5.8 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) rRNA_proc-arch PF13234.1 KFX97811.1 - 1.8e-101 338.8 0.0 3.2e-101 337.9 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 KFX97811.1 - 3e-62 209.0 0.7 5.7e-62 208.1 0.5 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KFX97811.1 - 8.6e-22 77.4 0.0 2.1e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX97811.1 - 1.5e-05 24.7 0.0 3.7e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prp19 PF08606.6 KFX97811.1 - 0.0035 17.0 0.6 0.35 10.6 0.1 2.7 2 0 0 2 2 2 1 Prp19/Pso4-like T2SE PF00437.15 KFX97811.1 - 0.0039 16.1 0.0 0.032 13.1 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein COX7C PF02935.11 KFX97812.1 - 5e-16 58.2 1.2 9.2e-16 57.3 0.9 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Chorismate_synt PF01264.16 KFX97813.1 - 2.2e-128 427.5 0.0 2.8e-128 427.2 0.0 1.1 1 0 0 1 1 1 1 Chorismate synthase Dicty_CAR PF05462.6 KFX97815.1 - 3.6e-12 45.8 8.1 3.6e-12 45.8 5.6 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor 7tm_1 PF00001.16 KFX97815.1 - 2.5e-07 30.1 1.6 3.5e-07 29.6 1.1 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 KFX97815.1 - 5.7e-05 22.7 10.9 5.7e-05 22.7 7.6 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Adeno_E3_CR2 PF02439.10 KFX97815.1 - 0.092 12.2 0.1 0.27 10.7 0.1 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Ank_2 PF12796.2 KFX97830.1 - 2.3e-08 34.2 0.0 1.4e-07 31.6 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFX97830.1 - 4.7e-06 26.1 0.0 0.043 13.6 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KFX97830.1 - 1.8e-05 24.7 0.0 8.7e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX97830.1 - 0.0051 16.9 0.0 17 6.0 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 KFX97830.1 - 0.042 14.3 0.0 3 8.4 0.0 2.8 1 1 2 3 3 3 0 Ankyrin repeats (many copies) DUF4078 PF13300.1 KFX97830.1 - 0.82 9.8 5.7 13 5.9 0.4 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4078) E1-E2_ATPase PF00122.15 KFX97832.1 - 7.5e-61 205.0 1.8 7.5e-61 205.0 1.2 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFX97832.1 - 3.2e-40 137.5 11.9 1e-39 135.9 2.2 3.0 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFX97832.1 - 1.3e-25 91.0 0.0 2e-24 87.2 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFX97832.1 - 3.3e-18 65.4 0.0 7e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFX97832.1 - 2.3e-15 57.3 0.0 9.5e-15 55.2 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFX97832.1 - 3.9e-06 26.6 0.8 5.5e-05 22.8 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFX97832.1 - 5.1e-06 25.8 0.1 8.2e-05 21.9 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus YjgP_YjgQ PF03739.9 KFX97832.1 - 0.072 11.8 5.5 0.14 10.8 0.9 2.5 3 0 0 3 3 3 0 Predicted permease YjgP/YjgQ family DevR PF01905.11 KFX97832.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 DUF2976 PF11190.3 KFX97832.1 - 0.19 11.2 9.2 0.4 10.2 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) DUF202 PF02656.10 KFX97832.1 - 0.25 11.5 1.2 1.2 9.4 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF202) HECT PF00632.20 KFX97834.1 - 2.4e-90 302.9 0.0 3.4e-90 302.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KFX97834.1 - 8.3e-32 108.6 16.2 1.2e-10 41.0 0.2 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.25 KFX97834.1 - 1.3e-15 56.9 0.0 3.3e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain Lipase_GDSL_2 PF13472.1 KFX97835.1 - 5.6e-14 52.6 0.1 1.3e-13 51.5 0.1 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFX97835.1 - 2.7e-09 37.2 0.0 4.1e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KFX97835.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Disulph_isomer PF06491.6 KFX97836.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Disulphide isomerase Tcf25 PF04910.9 KFX97837.1 - 5.5e-77 259.1 0.1 1.1e-76 258.0 0.1 1.5 1 0 0 1 1 1 1 Transcriptional repressor TCF25 RNase_H2-Ydr279 PF09468.5 KFX97837.1 - 9.5 5.3 13.5 16 4.6 9.3 1.3 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) PP2C PF00481.16 KFX97838.1 - 1.2e-37 129.7 0.0 2.1e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KFX97838.1 - 0.0025 17.2 0.0 0.0062 15.9 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KFX97838.1 - 0.0066 16.1 0.0 1.8 8.1 0.0 2.9 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) DUF3954 PF13128.1 KFX97838.1 - 0.079 12.3 0.0 0.2 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3954) RasGEF PF00617.14 KFX97839.1 - 1.5e-55 187.8 2.9 2.1e-55 187.3 0.2 2.4 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 KFX97839.1 - 2.9e-19 69.0 0.4 8.5e-19 67.5 0.0 2.0 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.23 KFX97839.1 - 0.00076 18.8 0.0 0.0019 17.5 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFX97839.1 - 0.0079 15.7 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFX97839.1 - 0.25 10.8 0.0 0.51 9.8 0.0 1.5 1 0 0 1 1 1 0 Variant SH3 domain PLAC8 PF04749.12 KFX97844.1 - 1.7e-15 57.4 12.3 2.3e-15 57.0 8.5 1.2 1 0 0 1 1 1 1 PLAC8 family 7TM_GPCR_Srd PF10317.4 KFX97844.1 - 0.11 11.4 0.4 0.2 10.6 0.3 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd Ycf1 PF05758.7 KFX97845.1 - 0.0041 14.9 8.4 0.0039 14.9 5.8 1.1 1 0 0 1 1 1 1 Ycf1 Hid1 PF12722.2 KFX97845.1 - 0.13 9.9 11.6 0.14 9.8 8.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Coiled PF05710.7 KFX97845.1 - 0.13 12.6 0.7 0.27 11.7 0.5 1.5 1 0 0 1 1 1 0 Coiled coil FAM60A PF15396.1 KFX97845.1 - 0.66 9.6 13.9 1.1 8.9 9.6 1.4 1 0 0 1 1 1 0 Protein Family FAM60A TIP120 PF08623.5 KFX97846.1 - 3.4e-63 212.2 0.8 1.3e-61 207.1 0.1 3.3 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 KFX97846.1 - 7.3e-13 48.6 21.8 0.11 12.8 0.0 9.7 9 2 1 11 11 10 5 HEAT repeats HEAT PF02985.17 KFX97846.1 - 4e-11 42.0 13.4 0.55 10.4 0.0 10.9 11 0 0 11 11 11 2 HEAT repeat DUF2435 PF10363.4 KFX97846.1 - 4.3e-05 23.3 10.6 1 9.2 0.0 6.7 6 1 1 7 7 7 2 Protein of unknown function (DUF2435) Proteasom_PSMB PF10508.4 KFX97846.1 - 0.0001 20.7 0.4 0.16 10.2 0.0 3.5 3 1 0 3 3 3 2 Proteasome non-ATPase 26S subunit Cnd1 PF12717.2 KFX97846.1 - 0.00015 21.6 8.7 0.17 11.6 0.0 5.5 6 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 KFX97846.1 - 0.00027 21.2 1.6 2.8 8.3 0.0 6.3 6 3 0 6 6 6 1 Vacuolar 14 Fab1-binding region DUF3554 PF12074.3 KFX97846.1 - 0.027 13.9 5.0 0.035 13.5 0.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3554) MIF4G PF02854.14 KFX97846.1 - 0.24 10.7 1.1 0.88 8.9 0.1 2.4 3 0 0 3 3 3 0 MIF4G domain DUF2457 PF10446.4 KFX97846.1 - 0.88 8.2 6.2 1.4 7.5 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HEAT_EZ PF13513.1 KFX97846.1 - 1.4 9.5 36.0 7.7 7.1 0.0 12.1 11 4 3 14 14 14 0 HEAT-like repeat zf-C2H2_6 PF13912.1 KFX97847.1 - 0.00027 20.7 2.7 0.00079 19.2 0.2 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger SpoVR PF04293.8 KFX97847.1 - 0.0035 15.7 0.1 0.0046 15.3 0.1 1.2 1 0 0 1 1 1 1 SpoVR like protein zf-met PF12874.2 KFX97847.1 - 0.13 12.4 5.9 2.3 8.5 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KFX97847.1 - 1.1 9.7 3.8 3.4 8.1 0.2 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-DHHC PF01529.15 KFX97849.1 - 3.4e-43 147.0 6.0 4.9e-43 146.5 4.1 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 KFX97849.1 - 0.029 14.1 0.6 0.077 12.8 0.4 1.7 1 0 0 1 1 1 0 Transglutaminase-like superfamily DZR PF12773.2 KFX97849.1 - 0.059 13.1 6.3 0.14 11.9 4.4 1.6 1 0 0 1 1 1 0 Double zinc ribbon Cyclin PF08613.6 KFX97850.1 - 3.2e-16 60.0 0.0 4.7e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KFX97850.1 - 0.0035 16.9 0.0 0.0054 16.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Chs3p PF12271.3 KFX97852.1 - 2.2e-140 466.7 14.9 2.5e-140 466.5 10.3 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF3382 PF11862.3 KFX97852.1 - 5.3 7.0 10.5 0.9 9.4 2.2 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3382) Zn_clus PF00172.13 KFX97854.1 - 9.1e-10 38.2 9.1 1.3e-09 37.7 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAF-1_p150 PF11600.3 KFX97854.1 - 0.17 11.2 0.7 0.21 10.9 0.5 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Opy2 PF09463.5 KFX97854.1 - 2.9 8.0 6.2 0.45 10.6 1.3 1.8 2 0 0 2 2 2 0 Opy2 protein F-box-like PF12937.2 KFX97855.1 - 0.00094 18.8 1.1 0.0018 17.9 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KFX97855.1 - 0.012 15.2 0.0 0.012 15.2 0.0 2.3 3 0 0 3 3 3 0 F-box domain PRANC PF09372.5 KFX97855.1 - 0.013 15.4 0.4 0.022 14.7 0.3 1.3 1 0 0 1 1 1 0 PRANC domain zf-C2H2_4 PF13894.1 KFX97857.1 - 5.9e-06 26.2 13.4 0.045 14.0 0.3 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFX97857.1 - 1.5e-05 25.0 5.8 0.0016 18.5 0.3 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFX97857.1 - 0.0011 19.0 3.4 0.031 14.4 0.2 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFX97857.1 - 0.016 15.0 0.5 0.016 15.0 0.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFX97857.1 - 0.02 15.2 19.2 0.076 13.3 1.1 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type Plasmodium_Vir PF05795.6 KFX97857.1 - 0.022 13.9 0.1 0.049 12.8 0.1 1.6 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Tetraspannin PF00335.15 KFX97857.1 - 0.19 10.9 0.3 0.33 10.2 0.2 1.4 1 0 0 1 1 1 0 Tetraspanin family HIG_1_N PF04588.8 KFX97859.1 - 1.7e-07 30.8 1.3 3.3e-07 29.9 0.9 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Kelch_4 PF13418.1 KFX97860.1 - 5.9e-41 138.0 19.8 3e-10 39.6 0.1 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 KFX97860.1 - 1.1e-40 136.8 23.2 5.6e-09 35.9 0.0 7.5 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.20 KFX97860.1 - 3.8e-40 135.1 16.5 2.1e-07 30.3 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 KFX97860.1 - 6.1e-39 131.4 15.1 8.8e-07 28.7 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KFX97860.1 - 3.9e-32 109.0 17.5 8.7e-07 28.8 0.1 6.3 3 2 3 6 6 6 6 Kelch motif Kelch_2 PF07646.10 KFX97860.1 - 1.7e-31 106.7 13.7 2.3e-06 27.1 0.1 6.4 6 0 0 6 6 6 6 Kelch motif K1377 PF15352.1 KFX97860.1 - 1.3 6.8 6.2 0.41 8.5 2.4 1.4 1 1 0 1 1 1 0 Susceptibility to monomelic amyotrophy SOG2 PF10428.4 KFX97860.1 - 4 5.9 11.0 6.8 5.2 7.6 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Dus PF01207.12 KFX97861.1 - 1.8e-39 135.4 0.0 7.9e-29 100.4 0.0 2.7 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) GFO_IDH_MocA PF01408.17 KFX97862.1 - 7.5e-10 39.3 0.0 1.7e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KFX97862.1 - 3.3e-05 23.6 0.0 8.5e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PGM_PMM_I PF02878.11 KFX97863.1 - 2e-31 108.3 0.3 4e-31 107.3 0.0 1.7 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I RNase_T PF00929.19 KFX97863.1 - 3.5e-26 92.4 0.1 8.9e-26 91.1 0.1 1.7 1 0 0 1 1 1 1 Exonuclease PGM_PMM_III PF02880.11 KFX97863.1 - 1.2e-23 83.3 0.0 2.5e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 KFX97863.1 - 1.4e-16 60.7 1.0 2.5e-16 59.8 0.1 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KFX97863.1 - 4.7e-11 42.5 0.0 1.3e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Atg31 PF09795.4 KFX97863.1 - 0.033 13.9 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 31 Ank_5 PF13857.1 KFX97864.1 - 1.3e-19 69.7 0.1 3.1e-11 43.1 0.0 5.0 4 1 1 5 5 5 3 Ankyrin repeats (many copies) VPS9 PF02204.13 KFX97864.1 - 1.1e-14 54.2 0.0 2.3e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.2 KFX97864.1 - 3e-14 53.1 0.0 1.3e-05 25.4 0.0 3.1 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFX97864.1 - 3.8e-11 43.1 0.1 0.0012 19.3 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX97864.1 - 3.8e-11 42.0 0.1 0.35 11.2 0.0 6.0 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.25 KFX97864.1 - 4.7e-09 35.5 0.3 0.004 16.8 0.0 5.5 5 1 0 5 5 5 1 Ankyrin repeat PX PF00787.19 KFX97864.1 - 0.0039 16.9 0.2 0.017 14.9 0.0 2.2 2 0 0 2 2 2 1 PX domain Fungal_trans_2 PF11951.3 KFX97865.1 - 1.1e-05 24.2 1.8 1.2e-05 24.1 0.7 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Ctr PF04145.10 KFX97866.1 - 2.9e-33 114.9 0.1 5.4e-33 114.0 0.1 1.4 1 1 0 1 1 1 1 Ctr copper transporter family Sod_Fe_C PF02777.13 KFX97867.1 - 4e-33 113.4 0.2 7.3e-33 112.5 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KFX97867.1 - 1.4e-32 111.7 2.7 3.1e-32 110.6 1.9 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Spt4 PF06093.8 KFX97878.1 - 2.3e-32 110.6 0.4 2.8e-32 110.4 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-DHHC PF01529.15 KFX97878.1 - 0.28 10.5 1.6 0.38 10.1 1.1 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase Kin17_mid PF10357.4 KFX97879.1 - 2.5e-50 169.3 0.8 2.5e-50 169.3 0.6 1.6 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 KFX97879.1 - 1.7e-05 24.8 3.2 4.4e-05 23.5 2.2 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFX97879.1 - 2.8e-05 24.0 2.4 2.8e-05 24.0 1.6 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFX97879.1 - 0.012 15.6 0.4 0.012 15.6 0.3 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Ecl1 PF12855.2 KFX97879.1 - 0.1 11.9 0.3 0.23 10.7 0.2 1.5 1 0 0 1 1 1 0 Life-span regulatory factor Xan_ur_permease PF00860.15 KFX97880.1 - 8.7e-25 87.0 25.5 4.4e-24 84.6 17.7 2.1 1 1 0 1 1 1 1 Permease family DUF605 PF04652.11 KFX97881.1 - 2.3e-65 221.4 21.3 2.6e-65 221.2 14.8 1.0 1 0 0 1 1 1 1 Vta1 like Acyl-CoA_dh_1 PF00441.19 KFX97901.1 - 3.6e-18 66.0 0.0 1.1e-17 64.5 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFX97901.1 - 2.3e-05 23.8 0.0 0.16 11.5 0.0 3.1 3 0 0 3 3 3 2 Acyl-CoA dehydrogenase, middle domain AMP-binding PF00501.23 KFX97902.1 - 2.4e-49 167.8 0.0 3.5e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Mito_carr PF00153.22 KFX97903.1 - 9.1e-62 204.8 0.3 1.9e-20 72.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3792 PF12670.2 KFX97903.1 - 0.25 11.1 2.5 0.51 10.2 0.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) Acyl-CoA_dh_N PF02771.11 KFX97904.1 - 6.4e-25 87.9 0.1 1.2e-24 87.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 KFX97904.1 - 1.4e-24 86.8 0.1 2.3e-24 86.1 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFX97904.1 - 8.6e-17 60.4 0.0 1.8e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFX97904.1 - 2.6e-08 34.2 0.2 4.1e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MARVEL PF01284.18 KFX97905.1 - 3.7e-14 52.7 15.3 6.2e-14 52.0 10.6 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF454 PF04304.8 KFX97905.1 - 0.0077 16.2 0.8 0.0077 16.2 0.6 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF454) ABC2_membrane_5 PF13346.1 KFX97905.1 - 0.11 11.8 11.5 0.38 9.9 8.1 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF3487 PF11990.3 KFX97905.1 - 0.16 11.4 3.4 0.13 11.6 0.9 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3487) YMF19 PF02326.10 KFX97905.1 - 0.31 11.6 0.0 0.31 11.6 0.0 2.2 2 0 0 2 2 2 0 Plant ATP synthase F0 Aldo_ket_red PF00248.16 KFX97920.1 - 2.4e-57 193.9 0.0 2.9e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Porin_OmpL1 PF11389.3 KFX97920.1 - 0.14 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Leptospira porin protein OmpL1 Maf PF02545.9 KFX97922.1 - 2.1e-38 131.3 0.0 2.4e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein EF-1_beta_acid PF10587.4 KFX97922.1 - 0.13 12.4 3.7 0.27 11.4 2.6 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Ada3 PF10198.4 KFX97923.1 - 4.9e-38 129.8 0.5 4.9e-38 129.8 0.3 2.3 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 zf-RING_2 PF13639.1 KFX97924.1 - 5.2e-14 51.7 6.5 9.5e-14 50.9 4.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFX97924.1 - 5.9e-08 32.6 6.4 5.9e-08 32.6 4.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX97924.1 - 1.3e-06 27.9 5.4 1.3e-06 27.9 3.7 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFX97924.1 - 4e-06 26.8 2.9 1.1e-05 25.4 2.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KFX97924.1 - 6.2e-06 25.8 4.5 1.2e-05 24.9 3.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFX97924.1 - 1.7e-05 24.4 3.8 3.6e-05 23.3 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFX97924.1 - 0.0014 18.3 4.0 0.0037 17.0 2.7 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KFX97924.1 - 0.0027 17.3 5.2 0.0027 17.3 3.6 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFX97924.1 - 0.0036 17.1 5.3 0.0095 15.7 3.7 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KFX97924.1 - 0.078 12.5 2.9 0.16 11.5 2.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 KFX97924.1 - 0.12 12.4 2.3 0.21 11.6 1.6 1.4 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 KFX97924.1 - 0.21 11.2 3.4 0.39 10.4 2.4 1.5 1 0 0 1 1 1 0 PHD-finger zf-Nse PF11789.3 KFX97924.1 - 0.22 11.0 7.3 0.59 9.6 3.9 2.4 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.6 KFX97924.1 - 8.4 6.4 7.6 0.46 10.5 1.1 1.9 2 0 0 2 2 2 0 RING-like domain Methyltransf_2 PF00891.13 KFX97929.1 - 4.3e-23 81.7 0.0 6.2e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KFX97929.1 - 6.4e-05 22.7 0.4 0.00025 20.8 0.3 2.0 1 0 0 1 1 1 1 Dimerisation domain MarR_2 PF12802.2 KFX97929.1 - 0.0019 17.8 0.0 0.0047 16.5 0.0 1.6 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.1 KFX97929.1 - 0.0047 16.2 0.0 0.013 14.8 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding MarR PF01047.17 KFX97929.1 - 0.054 13.2 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_IclR PF09339.5 KFX97929.1 - 0.056 13.0 0.7 0.24 11.0 0.0 2.4 3 0 0 3 3 3 0 IclR helix-turn-helix domain HTH_20 PF12840.2 KFX97929.1 - 0.14 11.9 0.5 0.56 10.0 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain APH PF01636.18 KFX97930.1 - 2.6e-06 27.3 0.0 4.4e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Nsp1_C PF05064.8 KFX97933.1 - 4.2e-38 129.5 0.7 4.2e-38 129.5 0.5 1.7 2 1 0 2 2 2 1 Nsp1-like C-terminal region MscS_porin PF12795.2 KFX97933.1 - 0.0067 15.7 5.5 0.34 10.1 0.1 2.3 2 0 0 2 2 2 2 Mechanosensitive ion channel porin domain CRIC_ras_sig PF10534.4 KFX97933.1 - 0.018 15.0 0.1 0.072 13.1 0.1 2.0 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras GAS PF13851.1 KFX97933.1 - 0.031 13.4 2.5 0.94 8.6 0.3 2.4 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding COG2 PF06148.6 KFX97933.1 - 0.044 13.6 3.4 1.4 8.7 1.8 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Tropomyosin_1 PF12718.2 KFX97933.1 - 0.046 13.5 2.2 0.067 13.0 0.7 1.9 1 1 1 2 2 2 0 Tropomyosin like Myosin_tail_1 PF01576.14 KFX97933.1 - 0.05 11.3 5.2 0.11 10.2 3.6 1.4 1 1 0 1 1 1 0 Myosin tail Laminin_II PF06009.7 KFX97933.1 - 0.052 13.3 4.3 2.1 8.0 0.4 3.0 1 1 2 3 3 3 0 Laminin Domain II Baculo_PEP_C PF04513.7 KFX97933.1 - 0.062 13.1 0.6 0.7 9.7 0.1 2.3 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nucleoporin_FG PF13634.1 KFX97933.1 - 0.1 12.8 11.9 0.22 11.7 8.3 1.5 1 0 0 1 1 1 0 Nucleoporin FG repeat region Spc7 PF08317.6 KFX97933.1 - 0.12 11.0 5.7 0.55 8.8 0.2 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1664 PF07889.7 KFX97933.1 - 0.13 12.0 1.7 4.1 7.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Muted PF14942.1 KFX97933.1 - 0.25 11.2 2.5 2 8.3 0.1 2.6 1 1 2 3 3 3 0 Organelle biogenesis, Muted-like protein HSBP1 PF06825.7 KFX97933.1 - 0.29 10.7 1.5 0.58 9.7 0.2 2.1 2 0 0 2 2 2 0 Heat shock factor binding protein 1 APG6 PF04111.7 KFX97933.1 - 0.3 10.1 6.7 0.12 11.3 1.9 1.8 1 1 1 2 2 2 0 Autophagy protein Apg6 Fib_alpha PF08702.5 KFX97933.1 - 0.34 11.0 1.3 6.2 6.9 0.1 2.7 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family ParB PF08775.5 KFX97933.1 - 0.37 11.1 2.1 0.5 10.6 0.1 2.0 2 1 0 2 2 2 0 ParB family MSP1_C PF07462.6 KFX97933.1 - 0.69 8.2 5.4 1.4 7.2 3.7 1.4 1 1 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus ERM PF00769.14 KFX97933.1 - 2.3 7.6 8.0 2.1 7.8 4.4 1.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family FAP PF07174.6 KFX97933.1 - 5.2 6.2 15.9 9.2 5.4 11.0 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) IncA PF04156.9 KFX97933.1 - 6.4 6.3 9.2 99 2.4 6.2 2.8 1 1 0 1 1 1 0 IncA protein TPR_MLP1_2 PF07926.7 KFX97933.1 - 7 6.3 12.2 8.4e+02 -0.4 8.4 2.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein IATP PF04568.7 KFX97934.1 - 3.1e-20 72.0 1.7 3.6e-20 71.8 1.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP NinG PF05766.7 KFX97934.1 - 0.013 15.2 0.9 0.016 14.9 0.6 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein RRF PF01765.14 KFX97934.1 - 0.04 13.3 3.1 0.053 12.9 2.1 1.2 1 0 0 1 1 1 0 Ribosome recycling factor Fib_alpha PF08702.5 KFX97934.1 - 0.059 13.4 0.0 0.059 13.4 0.0 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Atg14 PF10186.4 KFX97934.1 - 0.086 11.7 0.8 0.084 11.8 0.5 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Macoilin PF09726.4 KFX97934.1 - 0.24 9.6 3.7 0.26 9.5 2.5 1.1 1 0 0 1 1 1 0 Transmembrane protein 14-3-3 PF00244.15 KFX97935.1 - 4e-117 389.3 7.2 4.7e-117 389.1 5.0 1.0 1 0 0 1 1 1 1 14-3-3 protein Peptidase_M17_N PF02789.12 KFX97935.1 - 0.02 14.6 0.3 0.31 10.7 0.0 2.8 1 1 2 3 3 3 0 Cytosol aminopeptidase family, N-terminal domain TPR_19 PF14559.1 KFX97935.1 - 0.32 11.3 3.0 2.5 8.5 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3461 PF11944.3 KFX97935.1 - 3 7.7 7.1 1.7 8.4 0.2 3.0 2 1 1 4 4 4 0 Protein of unknown function (DUF3461) DSPn PF14671.1 KFX97936.1 - 7e-44 149.2 0.0 6e-41 139.7 0.0 3.2 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 KFX97936.1 - 5.7e-15 55.0 0.0 1.4e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFX97936.1 - 2.6e-06 26.9 0.0 5.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF3698 PF12479.3 KFX97936.1 - 0.15 12.2 0.1 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3698) Y_phosphatase3 PF13350.1 KFX97936.1 - 0.36 11.0 2.4 0.42 10.8 0.1 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family Pcc1 PF09341.5 KFX97937.1 - 6.6e-24 83.7 0.5 8.9e-24 83.3 0.4 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 Thioredoxin PF00085.15 KFX97938.1 - 3.3e-62 206.6 8.8 1.1e-30 105.3 0.0 4.1 5 0 0 5 5 5 3 Thioredoxin Thioredoxin_6 PF13848.1 KFX97938.1 - 1.2e-49 168.6 2.1 2.4e-35 121.9 0.4 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KFX97938.1 - 3.2e-11 43.4 2.6 0.00014 22.0 0.0 4.3 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFX97938.1 - 1.5e-10 41.0 0.1 0.0004 20.4 0.0 3.7 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KFX97938.1 - 5.8e-10 39.0 0.1 0.0032 17.4 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin-like Calsequestrin PF01216.12 KFX97938.1 - 1.8e-08 33.5 2.7 3.4e-08 32.6 1.3 1.8 1 1 1 2 2 2 1 Calsequestrin AhpC-TSA PF00578.16 KFX97938.1 - 1.3e-06 28.0 1.1 0.0073 15.9 0.0 3.4 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 KFX97938.1 - 0.00011 21.8 4.7 0.11 11.9 0.0 3.5 4 0 0 4 4 4 2 Redoxin Thioredoxin_4 PF13462.1 KFX97938.1 - 0.54 10.2 9.0 1.6 8.6 0.1 4.1 4 0 0 4 4 4 0 Thioredoxin DUF883 PF05957.8 KFX97938.1 - 1.4 9.3 12.3 0.027 14.8 3.2 2.2 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 KFX97938.1 - 2.9 8.3 10.5 0.37 11.1 3.0 2.7 2 0 0 2 2 2 0 YtxH-like protein PITH PF06201.8 KFX97940.1 - 4e-40 137.0 0.0 5.8e-40 136.5 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 KFX97940.1 - 1.8e-27 95.0 0.1 3.5e-27 94.1 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KFX97940.1 - 6.3e-09 35.8 0.1 1.6e-06 28.1 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KFX97940.1 - 2.4e-06 27.7 0.2 1.1e-05 25.5 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 KFX97940.1 - 0.00099 18.6 0.1 0.0028 17.2 0.0 1.8 2 0 0 2 2 2 1 Redoxin AhpC-TSA PF00578.16 KFX97940.1 - 0.0022 17.6 0.0 0.0049 16.5 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family HyaE PF07449.6 KFX97940.1 - 0.011 15.5 0.0 0.031 14.1 0.0 1.7 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.1 KFX97940.1 - 0.018 14.5 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.1 KFX97940.1 - 0.024 14.6 0.0 0.059 13.4 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like TPR_14 PF13428.1 KFX97941.1 - 2.4e-05 24.5 2.4 1.2 10.0 0.1 5.1 5 2 1 6 6 6 2 Tetratricopeptide repeat Suf PF05843.9 KFX97941.1 - 3.9e-05 23.5 3.9 0.075 12.7 0.0 2.9 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_16 PF13432.1 KFX97941.1 - 0.00019 22.0 2.1 0.01 16.4 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFX97941.1 - 0.014 15.6 0.0 4.2 7.7 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF998 PF06197.8 KFX97942.1 - 0.029 13.7 0.9 0.029 13.7 0.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF998) UPF0093 PF03653.8 KFX97942.1 - 0.049 13.5 0.2 0.057 13.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0093) DUF3756 PF12581.3 KFX97942.1 - 0.14 11.8 0.0 0.39 10.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3756) DUF202 PF02656.10 KFX97942.1 - 0.15 12.3 7.4 0.14 12.3 3.5 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Zn_clus PF00172.13 KFX97943.1 - 7.4e-08 32.1 6.5 1.1e-07 31.5 4.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3716 PF12511.3 KFX97943.1 - 0.073 12.6 4.1 0.12 11.9 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) DUF2763 PF10961.3 KFX97944.1 - 0.18 12.2 2.9 0.15 12.4 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) Mito_carr PF00153.22 KFX97959.1 - 3.8e-54 180.3 6.0 5.2e-20 70.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L6 PF00347.18 KFX97962.1 - 4.1e-27 94.4 9.3 1.5e-14 54.2 1.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Cyclin PF08613.6 KFX97963.1 - 6.6e-12 46.0 0.0 9.2e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KFX97963.1 - 0.0028 17.2 0.0 0.0043 16.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain PMSR PF01625.16 KFX97988.1 - 2.7e-59 199.5 0.2 3.2e-59 199.2 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase ArabFuran-catal PF09206.6 KFX97989.1 - 2.5e-141 470.3 23.7 3.6e-141 469.8 16.5 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 KFX97989.1 - 3.8e-56 188.7 1.3 6.1e-56 188.1 0.9 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) CLP_protease PF00574.18 KFX97992.1 - 4.8e-70 234.9 0.0 7.8e-70 234.2 0.0 1.3 1 1 0 1 1 1 1 Clp protease AbbA_antirepres PF14156.1 KFX97993.1 - 0.043 13.4 0.1 0.089 12.4 0.0 1.5 2 0 0 2 2 2 0 Antirepressor AbbA TPR_11 PF13414.1 KFX97994.1 - 2.7e-05 23.7 1.7 1.7 8.3 0.0 4.6 4 1 0 4 4 4 2 TPR repeat TPR_17 PF13431.1 KFX97994.1 - 8.1e-05 22.5 0.4 2.9 8.3 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFX97994.1 - 0.00025 20.9 1.5 0.96 9.4 0.0 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFX97994.1 - 0.0095 16.4 13.6 1.5 9.7 0.0 6.4 4 2 2 6 6 6 1 Tetratricopeptide repeat Nro1 PF12753.2 KFX97994.1 - 0.049 12.5 0.0 0.093 11.6 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 TPR_7 PF13176.1 KFX97994.1 - 0.17 11.7 3.1 84 3.3 0.0 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFX97994.1 - 0.88 10.1 0.1 0.88 10.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFX97994.1 - 1.3 9.8 12.9 1.2 9.9 0.2 4.7 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KFX97994.1 - 2.4 8.2 7.4 41 4.4 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat NUDIX PF00293.23 KFX97995.1 - 1.1e-14 54.2 0.0 1.5e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain KH_3 PF13014.1 KFX97995.1 - 0.15 11.7 0.1 3 7.6 0.0 2.5 2 0 0 2 2 2 0 KH domain Glyco_hydro_28 PF00295.12 KFX97996.1 - 1.6e-53 181.7 7.3 2.7e-53 181.0 5.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pkinase PF00069.20 KFX97996.1 - 9.1e-11 41.3 0.0 1.8e-10 40.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 KFX97996.1 - 1.8e-07 31.1 0.0 8.1e-05 22.4 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KFX97996.1 - 2.5e-06 26.7 0.0 4.3e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KFX97996.1 - 7.7e-06 25.3 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KFX97996.1 - 3.6e-05 22.9 0.0 0.00034 19.7 0.0 2.3 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KFX97996.1 - 0.0032 16.3 0.0 0.0066 15.3 0.0 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 KFX97996.1 - 0.0045 15.9 0.0 0.0068 15.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 KFX97996.1 - 0.0086 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF4066 PF13278.1 KFX97997.1 - 2.4e-30 105.0 0.0 3e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KFX97997.1 - 2.7e-08 33.3 0.0 4e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Glyco_hydro_11 PF00457.12 KFX97998.1 - 1.2e-78 262.6 24.6 1.4e-78 262.4 17.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF2147 PF09917.4 KFX97998.1 - 0.074 13.3 1.8 3.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2147) NmrA PF05368.8 KFX98005.1 - 1.7e-18 66.7 0.0 2.2e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX98005.1 - 1.2e-11 44.9 0.0 1.3e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX98005.1 - 5.1e-07 29.3 0.0 6.6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFX98005.1 - 3.9e-05 22.4 0.0 5e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 KFX98005.1 - 0.00057 20.2 0.1 0.0011 19.3 0.0 1.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.14 KFX98005.1 - 0.0018 17.3 0.1 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DapB_N PF01113.15 KFX98005.1 - 0.0084 16.0 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.15 KFX98005.1 - 0.017 15.2 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 KFX98005.1 - 0.018 15.3 0.0 0.023 14.9 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Choline_kin_N PF04428.9 KFX98005.1 - 0.039 13.4 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 Choline kinase N terminus RmlD_sub_bind PF04321.12 KFX98005.1 - 0.08 11.8 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Ldh_1_N PF00056.18 KFX98005.1 - 0.087 12.6 0.2 0.12 12.2 0.2 1.4 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.20 KFX98005.1 - 0.092 12.6 0.1 0.15 11.9 0.0 1.5 1 1 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.7 KFX98005.1 - 0.1 11.5 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein NAD_binding_2 PF03446.10 KFX98005.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Polysacc_synt_2 PF02719.10 KFX98005.1 - 0.16 10.8 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NMO PF03060.10 KFX98006.1 - 6.2e-31 107.7 3.7 7.7e-24 84.4 1.0 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.20 KFX98006.1 - 7.8e-06 25.0 1.2 0.11 11.3 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KFX98006.1 - 5e-05 22.3 3.2 7.4e-05 21.7 2.2 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KFX98006.1 - 0.00033 19.6 0.6 0.0005 19.0 0.4 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Antimicrobial15 PF08110.7 KFX98006.1 - 0.056 13.4 0.1 0.19 11.8 0.1 1.9 1 0 0 1 1 1 0 Ocellatin family NmrA PF05368.8 KFX98007.1 - 5.1e-39 133.9 0.0 6.1e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX98007.1 - 5.9e-07 29.6 0.1 8.4e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFX98007.1 - 4.5e-05 22.2 0.0 5.7e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KFX98007.1 - 0.0024 17.3 0.1 0.0031 16.9 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KFX98007.1 - 0.031 13.2 0.0 0.056 12.4 0.0 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KFX98007.1 - 0.05 13.9 0.2 0.11 12.7 0.1 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 KFX98007.1 - 0.075 12.6 0.5 0.27 10.8 0.1 1.9 2 0 0 2 2 2 0 KR domain FAD_binding_4 PF01565.18 KFX98008.1 - 1.1e-15 57.3 0.0 1.9e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.11 KFX98011.1 - 2.7e-34 118.4 32.1 2.7e-34 118.4 22.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Bestrophin PF01062.16 KFX98011.1 - 0.17 10.8 2.1 0.56 9.0 1.5 1.8 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel Cyclin PF08613.6 KFX98020.1 - 1.1e-14 55.0 0.1 2e-14 54.2 0.0 1.6 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KFX98020.1 - 0.0014 18.2 0.2 0.0029 17.1 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain DUF948 PF06103.6 KFX98023.1 - 0.0014 18.3 0.2 0.0027 17.5 0.2 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) DegS PF05384.6 KFX98023.1 - 0.011 14.9 0.6 0.019 14.2 0.4 1.3 1 0 0 1 1 1 0 Sensor protein DegS Cluap1 PF10234.4 KFX98023.1 - 0.022 13.9 2.3 0.037 13.2 1.6 1.3 1 0 0 1 1 1 0 Clusterin-associated protein-1 TBPIP PF07106.8 KFX98023.1 - 0.032 13.7 0.8 0.055 13.0 0.6 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-F_leu_zip PF10473.4 KFX98023.1 - 0.037 13.8 2.2 0.067 13.0 1.5 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APCDDC PF14921.1 KFX98023.1 - 0.059 12.7 0.0 0.18 11.1 0.0 1.7 2 0 0 2 2 2 0 Adenomatosis polyposis coli down-regulated 1 Cep57_CLD_2 PF14197.1 KFX98023.1 - 0.11 12.4 2.6 0.19 11.6 1.8 1.4 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Voltage_CLC PF00654.15 KFX98023.1 - 0.29 10.1 3.5 0.48 9.3 2.4 1.2 1 0 0 1 1 1 0 Voltage gated chloride channel COesterase PF00135.23 KFX98025.1 - 2.2e-78 264.3 0.2 3.1e-78 263.8 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX98025.1 - 7.3e-07 28.9 0.1 2.4e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX98025.1 - 0.00017 21.3 0.0 0.00035 20.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFX98025.1 - 0.034 13.3 0.1 0.064 12.4 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family p450 PF00067.17 KFX98030.1 - 2.4e-44 151.6 0.0 3.5e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Herpes_VP19C PF03327.9 KFX98031.1 - 0.055 12.3 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus capsid shell protein VP19C Cytochrom_B559 PF00283.14 KFX98031.1 - 0.2 10.9 0.9 0.36 10.1 0.6 1.4 1 0 0 1 1 1 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits Alpha-amylase PF00128.19 KFX98043.1 - 5.9e-23 81.7 1.3 3.3e-18 66.1 0.5 3.1 2 1 0 2 2 2 2 Alpha amylase, catalytic domain PA26 PF04636.8 KFX98043.1 - 0.21 10.2 0.1 0.33 9.6 0.1 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Polysacc_deac_1 PF01522.16 KFX98045.1 - 2.5e-24 85.2 0.0 3.8e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase HTH_39 PF14090.1 KFX98045.1 - 0.011 15.1 1.3 0.041 13.3 0.1 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain Polysacc_deac_2 PF04748.8 KFX98045.1 - 0.011 14.7 0.0 0.024 13.6 0.0 1.5 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Epimerase PF01370.16 KFX98046.1 - 4.1e-06 26.4 0.1 0.0064 15.9 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KFX98046.1 - 7e-05 22.1 0.0 0.00011 21.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 KFX98046.1 - 0.00035 20.8 0.0 0.00095 19.4 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KFX98046.1 - 0.002 16.9 0.5 0.22 10.1 0.1 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KFX98046.1 - 0.0073 15.2 0.0 0.022 13.7 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 KFX98047.1 - 4.5e-89 298.7 0.0 5.7e-89 298.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX98047.1 - 3.4e-10 40.7 2.0 1.1e-09 39.0 0.2 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Methyltransf_33 PF10017.4 KFX98049.1 - 2.2e-32 111.6 0.0 3.6e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 KFX98049.1 - 8.7e-19 67.8 0.4 8.9e-18 64.5 0.3 2.2 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 KFX98049.1 - 3.3e-07 30.7 0.1 7.4e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 DinB superfamily Methyltransf_25 PF13649.1 KFX98049.1 - 0.021 15.1 0.0 0.28 11.5 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 KFX98049.1 - 0.097 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RGS-like PF09128.6 KFX98050.1 - 0.036 13.5 0.1 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain GATA PF00320.22 KFX98051.1 - 1.3e-31 107.6 16.8 3.3e-16 58.3 2.6 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 KFX98051.1 - 3.8e-05 22.9 4.3 0.051 12.9 0.1 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.1 KFX98051.1 - 0.0002 20.4 5.3 0.21 10.8 0.6 2.7 2 0 0 2 2 2 2 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 KFX98051.1 - 0.0037 16.8 5.2 0.14 11.8 0.2 2.7 2 0 0 2 2 2 2 Putative transposase DNA-binding domain ArfGap PF01412.13 KFX98051.1 - 0.0043 16.8 8.0 0.14 11.8 0.1 2.9 3 0 0 3 3 3 2 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.5 KFX98051.1 - 0.0051 16.7 2.5 0.99 9.4 0.2 2.6 2 0 0 2 2 2 2 Zinc ribbon domain HypA PF01155.14 KFX98051.1 - 0.0082 15.8 1.7 1.9 8.2 0.1 2.4 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family RRN7 PF11781.3 KFX98051.1 - 0.01 15.2 6.7 0.64 9.5 0.4 2.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-Sec23_Sec24 PF04810.10 KFX98051.1 - 0.014 14.8 7.8 0.019 14.5 0.2 2.9 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger NMD3 PF04981.8 KFX98051.1 - 0.023 13.8 0.9 2 7.4 0.0 2.4 2 0 0 2 2 2 0 NMD3 family Zn_Tnp_IS1595 PF12760.2 KFX98051.1 - 0.067 13.0 5.3 0.36 10.6 0.6 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain eIF-5_eIF-2B PF01873.12 KFX98051.1 - 0.085 12.5 4.7 2 8.0 0.3 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 DZR PF12773.2 KFX98051.1 - 0.11 12.3 11.8 1.2 9.0 1.3 3.2 2 1 1 3 3 3 0 Double zinc ribbon Auto_anti-p27 PF06677.7 KFX98051.1 - 0.12 12.1 3.4 4.6 7.0 0.2 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Nucleo_P87 PF07267.6 KFX98051.1 - 9 4.8 10.1 0.28 9.8 2.8 1.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 COPI_assoc PF08507.5 KFX98052.1 - 8.8e-44 148.5 6.2 9.6e-44 148.4 4.3 1.0 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.4 KFX98052.1 - 0.011 15.6 3.2 0.016 15.1 2.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein CG6151-P Ycf66_N PF07444.6 KFX98052.1 - 0.17 11.6 2.2 0.36 10.5 1.5 1.7 1 1 0 1 1 1 0 Ycf66 protein N-terminus PGPGW PF09656.5 KFX98052.1 - 0.67 9.2 0.0 0.67 9.2 0.0 2.8 4 0 0 4 4 4 0 Putative transmembrane protein (PGPGW) DUF2583 PF10762.4 KFX98052.1 - 1 9.5 4.2 29 4.8 1.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) DUF3784 PF12650.2 KFX98052.1 - 2.5 8.1 9.5 0.26 11.2 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) PGAP1 PF07819.8 KFX98053.1 - 1.3e-05 24.9 0.0 3.3e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein NACHT PF05729.7 KFX98053.1 - 1.6e-05 24.6 0.1 3.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.9 KFX98053.1 - 3.2e-05 23.3 0.0 8.3e-05 21.9 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_16 PF13191.1 KFX98053.1 - 8.1e-05 22.6 0.0 0.00021 21.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain 6PF2K PF01591.13 KFX98053.1 - 0.00031 19.8 0.0 0.00089 18.3 0.0 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase Abhydrolase_6 PF12697.2 KFX98053.1 - 0.0032 17.3 0.1 0.012 15.4 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Arch_ATPase PF01637.13 KFX98053.1 - 0.0065 16.1 0.0 0.054 13.1 0.0 2.1 2 0 0 2 2 2 1 Archaeal ATPase WD40 PF00400.27 KFX98053.1 - 0.022 14.6 6.8 1.9 8.4 0.3 5.9 7 0 0 7 7 7 0 WD domain, G-beta repeat Abhydrolase_5 PF12695.2 KFX98053.1 - 0.049 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_33 PF13671.1 KFX98053.1 - 0.065 13.1 0.0 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF1664 PF07889.7 KFX98053.1 - 0.12 12.2 0.1 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fructosamin_kin PF03881.9 KFX98054.1 - 5.5e-35 120.7 0.0 7.9e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KFX98054.1 - 0.00052 19.8 0.0 0.00086 19.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Prothymosin PF03247.9 KFX98054.1 - 0.012 15.7 22.5 0.02 15.0 15.6 1.2 1 0 0 1 1 1 0 Prothymosin/parathymosin family BSP_II PF05432.6 KFX98054.1 - 0.014 14.6 13.2 0.025 13.8 9.1 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TLP-20 PF06088.6 KFX98054.1 - 0.062 12.9 0.5 0.1 12.2 0.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Sigma70_ner PF04546.8 KFX98054.1 - 0.096 12.2 10.4 0.15 11.6 7.2 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 KFX98054.1 - 0.12 10.4 5.4 0.16 9.9 3.7 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 KFX98054.1 - 0.43 9.7 8.6 0.65 9.1 6.0 1.2 1 0 0 1 1 1 0 NOA36 protein CobT PF06213.7 KFX98054.1 - 0.45 9.5 16.1 0.65 9.0 11.1 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ribosomal_60s PF00428.14 KFX98054.1 - 0.53 10.7 16.5 1.4 9.4 11.4 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein RNA_pol_3_Rpc31 PF11705.3 KFX98054.1 - 0.91 9.4 13.1 1.5 8.7 9.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FAM176 PF14851.1 KFX98054.1 - 1 9.0 6.9 1.6 8.3 4.8 1.3 1 0 0 1 1 1 0 FAM176 family DUF2457 PF10446.4 KFX98054.1 - 1.1 7.8 13.1 1.9 7.1 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 KFX98054.1 - 1.7 6.5 14.6 2.2 6.0 10.1 1.1 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.13 KFX98054.1 - 1.9 7.5 12.9 2.3 7.3 8.0 1.7 2 0 0 2 2 2 0 Myc amino-terminal region DNA_pol_phi PF04931.8 KFX98054.1 - 2.4 5.8 16.3 3.2 5.3 11.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nucleoplasmin PF03066.10 KFX98054.1 - 2.9 7.3 18.6 5.3 6.5 12.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 KFX98054.1 - 3.2 6.1 16.9 4.4 5.6 11.7 1.1 1 0 0 1 1 1 0 Daxx Family Prog_receptor PF02161.10 KFX98054.1 - 3.6 6.3 6.4 5.3 5.7 4.5 1.1 1 0 0 1 1 1 0 Progesterone receptor Radial_spoke PF04712.7 KFX98054.1 - 3.9 6.1 15.3 6 5.4 10.6 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Sporozoite_P67 PF05642.6 KFX98054.1 - 5.3 4.7 7.3 8.2 4.1 5.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pox_RNA_Pol_19 PF05320.7 KFX98054.1 - 5.4 6.7 11.0 9.6 5.9 7.6 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Pox_Ag35 PF03286.9 KFX98054.1 - 6.8 6.1 9.8 11 5.5 6.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Paf1 PF03985.8 KFX98054.1 - 7.4 5.1 16.5 11 4.6 11.4 1.1 1 0 0 1 1 1 0 Paf1 TRAP_alpha PF03896.11 KFX98054.1 - 8.6 5.2 10.6 13 4.6 7.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CENP-B_dimeris PF09026.5 KFX98054.1 - 8.9 6.6 19.6 20 5.4 13.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TFIIF_alpha PF05793.7 KFX98054.1 - 9.5 4.4 16.9 13 3.9 11.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HAD_2 PF13419.1 KFX98055.1 - 8.9e-07 29.2 0.0 1.6e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFX98055.1 - 2e-06 27.3 0.0 4.8e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 KFX98055.1 - 0.00035 21.0 0.0 0.00042 20.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Maf PF02545.9 KFX98055.1 - 0.12 11.4 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Maf-like protein MFS_1 PF07690.11 KFX98056.1 - 4.5e-15 55.2 26.5 4.9e-14 51.8 18.4 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX98056.1 - 5e-13 48.4 2.8 5e-13 48.4 1.9 2.3 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KFX98056.1 - 0.0018 16.5 0.4 0.0018 16.5 0.3 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) NAD_binding_10 PF13460.1 KFX98058.1 - 6.1e-07 29.6 0.0 8.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX98058.1 - 0.0018 17.7 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFX98058.1 - 0.0033 16.3 0.0 0.0086 15.0 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 KFX98058.1 - 0.0083 15.0 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.15 KFX98058.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DAO PF01266.19 KFX98059.1 - 2.3e-21 76.1 1.9 2.8e-21 75.8 1.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Coatomer_WDAD PF04053.9 KFX98065.1 - 7.5e-149 496.2 0.0 1.2e-148 495.6 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 KFX98065.1 - 1e-76 258.1 0.0 1.6e-76 257.5 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 KFX98065.1 - 5.7e-49 162.3 12.1 8.4e-09 34.9 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 KFX98065.1 - 0.0077 15.9 0.4 2.6 7.7 0.0 3.7 4 0 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFX98065.1 - 0.011 13.8 7.8 0.48 8.5 0.1 3.8 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Clathrin PF00637.15 KFX98065.1 - 0.02 14.5 2.3 0.052 13.1 0.0 2.5 3 0 0 3 3 3 0 Region in Clathrin and VPS MARVEL PF01284.18 KFX98065.1 - 0.045 13.5 9.0 0.088 12.6 6.3 1.4 1 0 0 1 1 1 0 Membrane-associating domain UDP-g_GGTase PF06427.6 KFX98066.1 - 1.8e-64 216.9 0.1 4.4e-64 215.6 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 KFX98066.1 - 7.6e-06 25.4 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mito_carr PF00153.22 KFX98067.1 - 3.1e-63 209.4 4.6 4.6e-23 80.7 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein APG9 PF04109.11 KFX98068.1 - 1.2e-168 560.7 1.2 1.7e-168 560.3 0.8 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 W2 PF02020.13 KFX98069.1 - 9.5e-18 63.9 1.8 3e-17 62.3 1.3 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 KFX98069.1 - 2.8e-07 29.7 11.4 0.059 12.8 1.2 4.3 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 KFX98069.1 - 2.8e-06 26.8 0.0 5.4e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 KFX98069.1 - 0.0073 16.3 0.0 0.02 14.9 0.0 1.8 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 KFX98069.1 - 0.01 15.3 8.7 0.33 10.5 0.3 3.4 2 1 2 4 4 4 0 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 KFX98069.1 - 0.3 9.6 3.3 1.3 7.4 0.3 2.1 1 1 1 2 2 2 0 L-fucokinase Mito_carr PF00153.22 KFX98070.1 - 3.6e-56 186.8 2.7 1.9e-22 78.7 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2783 PF10932.3 KFX98072.1 - 0.15 11.5 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2783) EI24 PF07264.6 KFX98073.1 - 0.00077 18.9 4.9 0.00077 18.9 3.4 2.4 2 0 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) AMP-binding PF00501.23 KFX98083.1 - 4.2e-80 269.1 0.0 5.8e-80 268.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KFX98083.1 - 2.9e-47 161.0 0.0 4.6e-47 160.3 0.0 1.3 1 0 0 1 1 1 1 Condensation domain NAD_binding_4 PF07993.7 KFX98083.1 - 5.5e-43 146.6 0.0 1.6e-42 145.1 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KFX98083.1 - 2.5e-18 66.0 0.7 2.8e-11 43.5 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.16 KFX98083.1 - 8.4e-18 64.6 0.0 3e-17 62.8 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family HxxPF_rpt PF13745.1 KFX98083.1 - 2.4e-10 40.5 0.0 8e-10 38.9 0.0 2.0 1 0 0 1 1 1 1 HxxPF-repeated domain 3Beta_HSD PF01073.14 KFX98083.1 - 1.3e-09 37.1 0.0 2.2e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFX98083.1 - 0.0044 17.0 0.0 0.0082 16.1 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KFX98083.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase MFS_1 PF07690.11 KFX98084.1 - 1.8e-42 145.3 50.4 1.8e-42 145.3 34.9 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX98084.1 - 1.4e-12 46.9 15.7 1.4e-12 46.9 10.9 2.7 1 1 2 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.8 KFX98084.1 - 0.00016 19.9 10.3 0.0003 19.0 7.2 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector DUF3500 PF12006.3 KFX98084.1 - 0.17 10.8 0.0 0.27 10.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) SAD_SRA PF02182.12 KFX98086.1 - 3.1e-22 78.5 0.1 5.4e-22 77.7 0.1 1.4 1 0 0 1 1 1 1 SAD/SRA domain Ribosomal_L18ae PF01775.12 KFX98087.1 - 5.1e-60 200.8 0.7 6.5e-60 200.4 0.5 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain PCI PF01399.22 KFX98088.1 - 1.4e-09 38.1 0.0 5.1e-09 36.3 0.0 2.0 1 0 0 1 1 1 1 PCI domain OTCace_N PF02729.16 KFX98088.1 - 0.12 12.0 0.0 0.34 10.5 0.0 1.7 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain BTB PF00651.26 KFX98089.1 - 3.7e-08 33.3 0.0 1.3e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.10 KFX98089.1 - 0.12 12.4 0.0 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain LRR_4 PF12799.2 KFX98090.1 - 7.2e-43 143.5 38.2 2.2e-10 39.9 1.2 6.7 4 1 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFX98090.1 - 2.8e-23 81.4 45.9 6.4e-08 32.2 1.8 5.0 1 1 4 6 6 6 5 Leucine rich repeat LRR_9 PF14580.1 KFX98090.1 - 5.6e-14 52.0 21.3 6e-05 22.6 1.1 3.2 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.1 KFX98090.1 - 5.8e-13 47.4 22.5 0.038 14.0 0.4 10.3 7 4 4 11 11 11 5 Leucine Rich repeat LRR_1 PF00560.28 KFX98090.1 - 4.3e-12 44.2 23.8 0.49 10.6 0.1 10.7 10 1 1 11 11 11 5 Leucine Rich Repeat LRR_7 PF13504.1 KFX98090.1 - 4.1e-09 35.1 13.1 1 9.8 0.1 9.7 10 0 0 10 10 10 1 Leucine rich repeat GTP-bdg_N PF13167.1 KFX98090.1 - 0.079 13.0 0.1 1.4 9.1 0.0 2.7 1 1 1 2 2 2 0 GTP-binding GTPase N-terminal FMN_dh PF01070.13 KFX98093.1 - 5.4e-99 331.4 0.0 1.5e-98 329.9 0.0 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KFX98093.1 - 3.8e-19 68.2 0.0 8.2e-19 67.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 KFX98093.1 - 1.5e-06 27.3 0.1 0.00071 18.5 0.0 3.0 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KFX98093.1 - 8.8e-06 24.8 0.0 1.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 KFX98093.1 - 0.047 12.6 0.0 0.19 10.6 0.0 1.8 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase ThiG PF05690.9 KFX98093.1 - 0.086 11.8 0.1 3.3 6.7 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Sugar_tr PF00083.19 KFX98094.1 - 5.8e-19 68.0 18.0 6.4e-19 67.8 12.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1440 PF07274.7 KFX98094.1 - 0.094 12.7 0.6 0.17 11.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1440) MFS_1 PF07690.11 KFX98094.1 - 1.8 7.1 18.4 0.014 14.0 5.3 1.6 1 1 1 2 2 2 0 Major Facilitator Superfamily MFS_1 PF07690.11 KFX98095.1 - 3.3e-36 124.7 28.3 8.9e-36 123.3 19.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.14 KFX98096.1 - 2.9e-10 39.7 0.0 0.0021 17.1 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 KFX98096.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KFX98096.1 - 0.056 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 KFX98096.1 - 0.06 13.7 0.0 0.36 11.2 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF3439 PF11921.3 KFX98096.1 - 0.11 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Orthoreo_P10 PF07204.6 KFX98096.1 - 0.17 11.6 0.1 0.34 10.6 0.0 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Rsm22 PF09243.5 KFX98097.1 - 5.6e-34 117.4 0.0 7.8e-33 113.6 0.0 2.7 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Ribosomal_S14 PF00253.16 KFX98100.1 - 8.4e-18 63.5 0.3 2e-17 62.3 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e adh_short PF00106.20 KFX98101.1 - 1.6e-14 54.1 0.1 1.1e-08 35.2 0.0 2.7 2 0 0 2 2 2 2 short chain dehydrogenase Acetyltransf_1 PF00583.19 KFX98101.1 - 9.5e-06 25.5 0.0 0.00019 21.4 0.0 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family adh_short_C2 PF13561.1 KFX98101.1 - 0.00043 20.1 0.0 0.0015 18.3 0.0 1.9 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX98101.1 - 0.00094 18.8 0.5 0.12 12.0 0.0 3.5 4 0 0 4 4 4 1 KR domain Epimerase PF01370.16 KFX98101.1 - 0.017 14.5 0.0 0.037 13.4 0.0 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Acetyltransf_10 PF13673.1 KFX98101.1 - 0.058 13.5 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Rpp20 PF12328.3 KFX98102.1 - 2.1e-30 105.2 0.8 2.7e-30 104.9 0.6 1.1 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 KFX98102.1 - 7.5e-16 57.4 0.1 1e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Alba Rogdi_lz PF10259.4 KFX98103.1 - 3e-53 180.6 0.0 4.3e-53 180.1 0.0 1.2 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Thioredoxin PF00085.15 KFX98104.1 - 7.7e-27 93.0 0.0 1.1e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KFX98104.1 - 2.4e-07 30.7 0.1 8.3e-05 22.6 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KFX98104.1 - 4.1e-07 30.1 0.1 1.7e-06 28.1 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 KFX98104.1 - 9.9e-05 21.9 0.1 0.044 13.3 0.1 2.2 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.16 KFX98104.1 - 0.00022 20.8 0.1 0.08 12.6 0.0 2.2 1 1 1 2 2 2 2 AhpC/TSA family HyaE PF07449.6 KFX98104.1 - 0.0046 16.8 0.0 0.0076 16.1 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.1 KFX98104.1 - 0.011 15.7 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like DUF2763 PF10961.3 KFX98104.1 - 0.012 15.9 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) Thioredoxin_9 PF14595.1 KFX98104.1 - 0.026 14.0 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.1 KFX98104.1 - 0.055 13.4 0.1 0.7 9.8 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_3 PF13192.1 KFX98104.1 - 0.092 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain Methyltrn_RNA_3 PF02598.12 KFX98105.1 - 8.2e-53 179.6 0.0 9.5e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Aconitase_B_N PF11791.3 KFX98105.1 - 0.097 12.4 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Aconitate B N-terminal domain Glyco_hydro_2_N PF02837.13 KFX98106.1 - 4.9e-11 42.4 0.0 1.3e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KFX98106.1 - 8.4e-08 32.6 0.0 5.1e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 KFX98106.1 - 1.8e-05 23.8 0.0 4.4e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Kinesin PF00225.18 KFX98107.1 - 8.5e-114 379.7 0.3 1.9e-113 378.5 0.2 1.6 1 0 0 1 1 1 1 Kinesin motor domain RolB_RolC PF02027.12 KFX98107.1 - 0.076 12.1 5.4 0.085 12.0 0.3 2.6 2 0 0 2 2 2 0 RolB/RolC glucosidase family UQ_con PF00179.21 KFX98108.1 - 1.1e-51 173.9 0.0 1.2e-51 173.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFX98108.1 - 4.2e-06 26.5 0.0 4.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFX98108.1 - 0.021 14.7 0.1 0.03 14.2 0.1 1.5 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 KFX98108.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 UEV domain Thiolase_N PF00108.18 KFX98109.1 - 1.7e-92 309.1 0.7 2.6e-92 308.5 0.5 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFX98109.1 - 1.6e-36 124.4 1.3 4e-36 123.1 0.9 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KFX98109.1 - 0.0072 15.8 2.7 0.0091 15.5 0.6 2.1 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain DJ-1_PfpI PF01965.19 KFX98110.1 - 9e-10 38.1 0.0 1.4e-09 37.5 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family COG5 PF10392.4 KFX98120.1 - 1e-40 138.7 1.5 3e-40 137.2 1.0 1.8 1 0 0 1 1 1 1 Golgi transport complex subunit 5 DUF1601 PF07671.6 KFX98120.1 - 0.036 13.6 0.0 0.1 12.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) DUF2434 PF10361.4 KFX98121.1 - 2.2e-119 397.9 2.0 3e-119 397.5 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) FA_hydroxylase PF04116.8 KFX98121.1 - 0.13 12.6 6.6 0.18 12.1 0.3 3.4 2 1 1 3 3 3 0 Fatty acid hydroxylase superfamily DUF805 PF05656.9 KFX98121.1 - 4 7.2 13.7 1.2 9.0 1.1 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF805) Thioredoxin PF00085.15 KFX98122.1 - 5.3e-25 87.1 0.0 6.5e-25 86.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KFX98122.1 - 6.1e-08 32.6 0.1 1.8e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KFX98122.1 - 1.6e-07 31.5 0.3 1.1e-06 28.7 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 KFX98122.1 - 1.6e-06 28.0 0.0 2.2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 KFX98122.1 - 1.7e-06 27.7 0.1 7.7e-06 25.6 0.0 1.7 1 1 1 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 KFX98122.1 - 2.6e-06 27.0 0.0 3.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.1 KFX98122.1 - 5.7e-05 22.6 0.0 7.3e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 KFX98122.1 - 0.00065 19.4 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain HyaE PF07449.6 KFX98122.1 - 0.024 14.5 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Phosducin PF02114.11 KFX98122.1 - 0.034 12.8 0.0 0.044 12.5 0.0 1.1 1 0 0 1 1 1 0 Phosducin TraF PF13728.1 KFX98122.1 - 0.14 11.6 0.0 0.23 10.8 0.0 1.4 1 1 0 1 1 1 0 F plasmid transfer operon protein DIM1 PF02966.11 KFX98122.1 - 0.14 11.6 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 adh_short PF00106.20 KFX98123.1 - 6.6e-14 52.1 2.1 1.6e-13 50.8 1.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX98123.1 - 1.1e-06 28.4 0.1 2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFX98123.1 - 0.00016 21.5 0.3 0.00024 20.9 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFX98123.1 - 0.00036 20.0 0.4 0.00093 18.6 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family MT0933_antitox PF14013.1 KFX98123.1 - 0.049 13.7 0.1 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 MT0933-like antitoxin protein Fungal_trans_2 PF11951.3 KFX98124.1 - 6.2e-25 87.6 8.2 4.4e-24 84.8 5.7 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.19 KFX98129.1 - 4e-44 150.3 20.2 5.7e-44 149.8 14.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KFX98129.1 - 6.2e-37 126.9 0.4 3.4e-18 66.2 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 KFX98129.1 - 7.6e-29 99.4 0.0 3.1e-28 97.4 0.0 2.0 2 0 0 2 2 1 1 CDR ABC transporter ABC_trans_N PF14510.1 KFX98129.1 - 1e-22 79.9 0.0 2.6e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 KFX98129.1 - 2.3e-07 30.1 0.2 4.5e-05 22.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFX98129.1 - 7.2e-07 29.3 1.5 5.9e-05 23.1 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KFX98129.1 - 1.4e-06 27.8 0.2 0.00026 20.4 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 KFX98129.1 - 5.2e-05 23.1 0.1 0.014 15.2 0.1 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KFX98129.1 - 0.00052 19.3 0.0 0.075 12.2 0.0 3.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFX98129.1 - 0.00058 19.3 0.5 0.16 11.5 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_19 PF13245.1 KFX98129.1 - 0.00073 19.2 1.4 0.14 11.9 0.1 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_21 PF13304.1 KFX98129.1 - 0.0011 19.0 0.1 2.1 8.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 KFX98129.1 - 0.0017 17.8 2.6 0.022 14.2 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KFX98129.1 - 0.0017 18.4 0.7 0.44 10.7 0.2 3.0 3 1 0 3 3 2 1 AAA domain ABC2_membrane_3 PF12698.2 KFX98129.1 - 0.0021 17.1 18.0 0.011 14.8 12.5 2.2 1 1 0 1 1 1 1 ABC-2 family transporter protein MMR_HSR1 PF01926.18 KFX98129.1 - 0.0022 17.9 0.1 1.9 8.4 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 KFX98129.1 - 0.0061 16.8 0.1 0.23 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFX98129.1 - 0.0092 16.8 0.0 0.17 12.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KFX98129.1 - 0.036 13.7 2.1 1.6 8.3 0.3 2.6 2 0 0 2 2 2 0 NACHT domain AAA_10 PF12846.2 KFX98129.1 - 0.037 13.4 4.2 8.1 5.7 0.3 3.4 3 0 0 3 3 3 0 AAA-like domain Arch_ATPase PF01637.13 KFX98129.1 - 0.039 13.6 0.0 9.6 5.8 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 KFX98129.1 - 0.044 13.3 0.1 7 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KFX98129.1 - 0.055 13.0 0.1 2.2 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KFX98129.1 - 0.07 12.0 0.1 3.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA PF00004.24 KFX98129.1 - 0.076 13.2 0.1 12 6.0 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KFX98129.1 - 0.08 12.9 0.2 0.68 9.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KFX98129.1 - 0.11 13.0 0.0 19 5.8 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein AAA_14 PF13173.1 KFX98129.1 - 0.14 12.0 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KFX98129.1 - 0.34 10.5 1.4 1.3 8.6 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Git3 PF11710.3 KFX98130.1 - 3.5e-08 33.2 6.2 6.1e-08 32.4 4.3 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 zf-CCCH_2 PF14608.1 KFX98131.1 - 8.7e-15 54.0 49.7 7.4e-08 32.1 6.8 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 KFX98131.1 - 0.0011 19.0 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) PAT1 PF09770.4 KFX98131.1 - 5 5.2 18.7 5.7 5.0 12.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HA2 PF04408.18 KFX98132.1 - 9.2e-24 83.4 0.0 3.3e-23 81.6 0.0 2.0 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KFX98132.1 - 4e-23 81.4 0.0 2.2e-22 79.0 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KFX98132.1 - 8.1e-09 35.2 0.0 2.1e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFX98132.1 - 2.4e-07 30.3 0.0 4.9e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFX98132.1 - 0.00099 19.2 0.1 0.0028 17.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 KFX98132.1 - 0.001 18.0 0.0 0.0024 16.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 KFX98132.1 - 0.0018 17.3 0.0 0.0034 16.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 KFX98132.1 - 0.0021 17.9 0.0 0.77 9.5 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SRP54 PF00448.17 KFX98132.1 - 0.021 14.2 0.2 0.05 13.0 0.1 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 KFX98132.1 - 0.024 14.4 0.1 0.048 13.4 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain NACHT PF05729.7 KFX98132.1 - 0.028 14.0 0.4 0.31 10.6 0.1 2.3 2 0 0 2 2 2 0 NACHT domain GAD PF02938.9 KFX98132.1 - 0.036 14.2 0.0 0.08 13.1 0.0 1.6 1 0 0 1 1 1 0 GAD domain NB-ARC PF00931.17 KFX98132.1 - 0.045 12.6 0.0 0.077 11.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.1 KFX98132.1 - 0.046 13.6 0.1 0.28 11.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KFX98132.1 - 0.05 13.9 0.6 0.41 10.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 KFX98132.1 - 0.055 13.7 0.0 0.22 11.8 0.0 2.0 2 0 0 2 2 1 0 ABC transporter DUF1570 PF07607.6 KFX98132.1 - 0.14 12.1 1.3 9.5 6.2 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1570) Ribosomal_L24e PF01246.15 KFX98134.1 - 1.1e-28 98.8 3.1 2.1e-28 97.9 2.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L24e Pam16 PF03656.8 KFX98135.1 - 4e-08 33.0 0.2 6.5e-08 32.4 0.1 1.3 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.26 KFX98135.1 - 1.1e-07 31.4 0.0 1.9e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF3918 PF13056.1 KFX98135.1 - 0.0094 15.2 2.0 0.0094 15.2 1.4 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3918) TMP_2 PF06791.8 KFX98135.1 - 0.11 12.0 1.9 0.13 11.8 1.3 1.4 1 1 0 1 1 1 0 Prophage tail length tape measure protein eIF3_p135 PF12807.2 KFX98136.1 - 2.3e-28 99.2 0.2 1.8e-27 96.3 0.0 2.4 2 1 1 3 3 3 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 KFX98136.1 - 8.9e-23 80.0 12.0 3.7e-11 42.8 1.4 3.8 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 KFX98136.1 - 1.1e-17 63.3 3.4 3.4e-06 26.8 0.1 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFX98136.1 - 6.9e-06 25.6 6.4 0.044 13.4 0.2 3.3 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.1 KFX98136.1 - 0.00021 20.8 4.1 0.14 12.0 0.2 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFX98136.1 - 0.0018 18.8 1.6 3.9 8.2 0.1 3.5 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFX98136.1 - 0.0029 17.4 11.3 0.055 13.3 0.1 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFX98136.1 - 0.01 15.4 3.7 1.9 8.2 0.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFX98136.1 - 0.19 12.0 2.3 36 4.9 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.11 KFX98138.1 - 1e-36 126.3 23.3 1.5e-36 125.8 16.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3169 PF11368.3 KFX98138.1 - 0.06 12.5 0.5 1.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Thiolase_N PF00108.18 KFX98139.1 - 2.1e-69 233.4 0.8 3.5e-69 232.7 0.5 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFX98139.1 - 2.3e-44 149.7 0.5 5.6e-44 148.5 0.3 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KFX98139.1 - 0.00096 18.7 0.2 0.043 13.4 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 KFX98139.1 - 0.0046 16.4 0.6 0.025 14.0 0.6 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 KFX98139.1 - 0.039 13.9 0.6 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal CBM_5_12 PF02839.9 KFX98140.1 - 0.034 13.7 0.2 0.069 12.7 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain DUF1370 PF07114.6 KFX98140.1 - 0.16 11.1 0.2 0.21 10.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1370) S6PP PF05116.8 KFX98141.1 - 0.046 13.0 0.0 0.061 12.6 0.0 1.1 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase DUF2370 PF10176.4 KFX98141.1 - 0.23 10.7 2.4 0.4 9.9 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF4243 PF14027.1 KFX98142.1 - 8.2e-83 278.5 2.2 1.1e-82 278.1 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) HECT_2 PF09814.4 KFX98143.1 - 1.3e-34 119.5 0.0 1.6e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding MFS_1 PF07690.11 KFX98146.1 - 6.9e-24 84.2 50.5 1.3e-23 83.3 33.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX98146.1 - 0.057 11.9 31.3 0.041 12.4 4.5 2.2 2 0 0 2 2 2 0 Sugar (and other) transporter Cytochrom_B558a PF05038.8 KFX98148.1 - 7.8 6.0 5.9 13 5.3 4.1 1.4 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit BCNT PF07572.7 KFX98149.1 - 3.7e-25 87.6 0.8 6e-25 86.9 0.6 1.2 1 0 0 1 1 1 1 Bucentaur or craniofacial development zf-RING_2 PF13639.1 KFX98151.1 - 3.1e-14 52.5 4.0 5.1e-14 51.8 2.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFX98151.1 - 2.6e-08 33.8 1.2 4.8e-08 33.0 0.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KFX98151.1 - 4.1e-07 29.5 3.2 6.7e-07 28.8 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX98151.1 - 1e-06 28.3 1.9 1.7e-06 27.6 1.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFX98151.1 - 1.9e-06 27.8 4.4 3.1e-06 27.0 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFX98151.1 - 1e-05 25.0 1.8 1.8e-05 24.3 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFX98151.1 - 0.0081 15.9 1.1 0.017 14.9 0.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KFX98151.1 - 0.014 15.0 2.7 0.023 14.2 1.9 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 KFX98151.1 - 0.099 12.6 2.7 0.18 11.8 1.9 1.4 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 KFX98151.1 - 0.21 11.3 2.5 0.4 10.4 1.8 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 KFX98151.1 - 0.78 9.5 4.5 3.7 7.3 3.3 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 KFX98151.1 - 0.81 9.6 3.8 5.4 7.0 2.7 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain CAP_GLY PF01302.20 KFX98152.1 - 1.3e-21 76.0 2.7 2e-21 75.4 1.9 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 KFX98152.1 - 5.2e-21 74.6 0.0 7.9e-21 74.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 KFX98152.1 - 8.5e-05 21.8 0.0 0.0002 20.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family EXOSC1 PF10447.4 KFX98154.1 - 4.5e-27 93.8 1.7 6.5e-27 93.3 1.2 1.2 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 KFX98154.1 - 2e-12 46.1 0.0 6.5e-12 44.5 0.0 1.9 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region tRNA_int_end_N2 PF12928.2 KFX98155.1 - 6e-22 76.8 0.0 1e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 KFX98155.1 - 0.013 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain zf-ZPR1 PF03367.8 KFX98156.1 - 9.2e-102 336.9 0.2 2.5e-52 176.2 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Elf1 PF05129.8 KFX98156.1 - 0.33 10.6 5.0 5.9 6.6 0.2 2.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Rpr2 PF04032.11 KFX98157.1 - 2.4e-14 52.9 2.8 3.7e-14 52.3 2.0 1.3 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nudix_N_2 PF14803.1 KFX98157.1 - 0.00092 18.8 0.4 0.00092 18.8 0.3 2.0 2 0 0 2 2 2 1 Nudix N-terminal FYVE PF01363.16 KFX98157.1 - 0.012 15.5 3.9 0.023 14.5 2.7 1.5 1 0 0 1 1 1 0 FYVE zinc finger C1_4 PF07975.7 KFX98157.1 - 0.7 9.9 4.8 1.4 8.9 0.3 2.6 2 1 0 2 2 2 0 TFIIH C1-like domain zf-HIT PF04438.11 KFX98157.1 - 2.1 8.0 5.2 7.5 6.2 0.1 2.6 2 0 0 2 2 2 0 HIT zinc finger DBR1 PF05011.8 KFX98158.1 - 5.6e-46 156.0 0.0 9.2e-46 155.3 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KFX98158.1 - 6.5e-09 35.4 0.5 1e-08 34.7 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GRP PF07172.6 KFX98158.1 - 8.1 7.0 29.3 16 6.0 20.3 1.4 1 0 0 1 1 1 0 Glycine rich protein family Skp1_POZ PF03931.10 KFX98159.1 - 6.9e-09 35.6 0.0 9.8e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain adh_short PF00106.20 KFX98160.1 - 4e-31 108.1 1.7 5.2e-31 107.8 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX98160.1 - 3.4e-27 95.7 0.1 4.2e-27 95.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX98160.1 - 4.2e-12 46.0 0.9 6.1e-12 45.5 0.6 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFX98160.1 - 2.6e-07 30.8 0.1 4.2e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX98160.1 - 1.9e-06 27.4 0.2 2.6e-05 23.7 0.1 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFX98160.1 - 0.00024 20.1 0.1 0.00032 19.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DFP PF04127.10 KFX98160.1 - 0.00066 19.3 0.3 0.0024 17.5 0.0 1.9 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein ApbA PF02558.11 KFX98160.1 - 0.002 17.6 0.1 0.0031 16.9 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Eno-Rase_NADH_b PF12242.3 KFX98160.1 - 0.0025 17.5 0.3 0.018 14.8 0.1 2.2 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 KFX98160.1 - 0.0045 16.6 0.2 0.0074 15.9 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KFX98160.1 - 0.015 15.4 0.2 0.058 13.4 0.2 1.9 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.7 KFX98160.1 - 0.029 13.3 0.6 0.077 11.9 0.4 1.6 1 1 0 1 1 1 0 Male sterility protein DapB_N PF01113.15 KFX98160.1 - 0.036 13.9 0.1 0.068 13.0 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 KFX98160.1 - 0.05 14.0 0.9 0.52 10.7 0.6 2.3 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 KFX98160.1 - 0.065 12.4 0.1 0.098 11.8 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family THF_DHG_CYH_C PF02882.14 KFX98160.1 - 0.075 12.1 0.1 1.1 8.3 0.1 2.2 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ThiF PF00899.16 KFX98161.1 - 1.1e-40 138.5 0.1 2.6e-40 137.3 0.1 1.7 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 KFX98161.1 - 1.3e-29 101.5 0.5 3.9e-29 100.0 0.4 1.9 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 KFX98161.1 - 1.4e-22 79.6 1.2 1.4e-22 79.6 0.9 1.8 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 KFX98161.1 - 1.3e-18 66.0 4.8 2.3e-18 65.2 0.4 2.4 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 KFX98161.1 - 0.00069 19.8 0.9 0.0024 18.1 0.0 2.4 3 0 0 3 3 3 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 KFX98161.1 - 0.0032 17.5 0.0 0.007 16.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KFX98161.1 - 0.076 13.4 0.1 1.4 9.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2419 PF10343.4 KFX98162.1 - 1.4e-130 434.7 0.7 1.6e-130 434.4 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) Spore_YhaL PF14147.1 KFX98162.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein YhaL Saccharop_dh PF03435.13 KFX98177.1 - 8.1e-25 87.6 0.3 1.1e-24 87.1 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KFX98177.1 - 0.0019 18.4 0.1 0.004 17.4 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 KFX98177.1 - 0.0021 17.7 0.1 0.0036 16.9 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFX98177.1 - 0.0023 17.4 0.1 0.0034 16.8 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KFX98177.1 - 0.0048 16.8 0.2 0.015 15.2 0.2 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KFX98177.1 - 0.015 14.2 0.1 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Aldolase PF01081.14 KFX98177.1 - 0.023 13.8 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 KDPG and KHG aldolase NmrA PF05368.8 KFX98177.1 - 0.027 13.7 0.6 0.063 12.5 0.4 1.7 1 1 0 1 1 1 0 NmrA-like family Ank PF00023.25 KFX98178.1 - 3.9e-08 32.7 0.0 0.68 9.8 0.0 5.5 4 2 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 KFX98178.1 - 9.7e-08 32.3 0.2 0.53 10.8 0.0 5.2 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFX98178.1 - 3.3e-07 30.5 0.0 0.0033 17.7 0.0 3.5 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFX98178.1 - 1.3e-06 28.0 0.3 37 4.9 0.0 6.6 6 0 0 6 6 6 0 Ankyrin repeat F-box-like PF12937.2 KFX98178.1 - 0.018 14.7 0.6 0.069 12.8 0.0 2.3 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 KFX98178.1 - 0.031 13.9 0.5 0.076 12.7 0.0 1.9 2 0 0 2 2 2 0 F-box domain Asp PF00026.18 KFX98179.1 - 3.3e-70 236.8 7.0 4e-70 236.5 4.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFX98179.1 - 1.5e-09 38.0 0.0 6.1e-09 36.0 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KFX98179.1 - 0.0002 21.8 1.4 0.0043 17.5 0.3 3.0 2 1 0 2 2 2 1 Aspartyl protease RHD3 PF05879.7 KFX98180.1 - 0 1045.5 0.0 0 1045.3 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 KFX98180.1 - 6.9e-08 31.8 0.1 1.1e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 KFX98180.1 - 7.7e-06 25.8 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KFX98180.1 - 0.00023 21.0 0.0 0.0005 20.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFX98180.1 - 0.0058 17.1 0.0 0.012 16.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 KFX98180.1 - 0.0087 16.0 0.0 0.031 14.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain DSBA PF01323.15 KFX98180.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain RNase_HII PF01351.13 KFX98181.1 - 6.4e-60 202.1 0.0 1.1e-39 136.1 0.0 3.1 2 1 1 3 3 3 3 Ribonuclease HII DUF3323 PF11796.3 KFX98181.1 - 0.15 11.3 0.0 0.8 8.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) CENP-C_C PF11699.3 KFX98182.1 - 9.3e-31 105.6 0.0 1.4e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 KFX98182.1 - 1.1e-27 97.3 1.5 1.1e-27 97.3 1.0 3.4 3 0 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 KFX98182.1 - 2.1e-10 39.9 0.0 3.9e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KFX98182.1 - 0.00049 19.5 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 KFX98182.1 - 0.016 14.5 0.0 0.046 13.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Cupin_6 PF12852.2 KFX98182.1 - 0.11 12.1 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Cupin Fructosamin_kin PF03881.9 KFX98183.1 - 9.8e-72 241.3 0.0 1.1e-71 241.2 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KFX98183.1 - 1.1e-05 25.3 0.0 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KFX98183.1 - 0.0088 14.7 0.0 0.014 14.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) TAF4 PF05236.9 KFX98184.1 - 5.1e-15 55.4 0.0 3.2e-12 46.2 0.0 3.1 2 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.3 KFX98185.1 - 3.3e-75 252.1 0.0 1.5e-72 243.5 0.0 2.2 2 0 0 2 2 2 2 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 KFX98185.1 - 5.4e-33 113.6 0.0 2.5e-32 111.4 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 KFX98185.1 - 6.6e-15 55.2 0.4 6.6e-15 55.2 0.3 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFX98185.1 - 5.1e-11 42.4 0.4 1.1e-10 41.4 0.3 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 KFX98185.1 - 1.2e-07 31.4 0.3 2.3e-07 30.5 0.2 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 KFX98185.1 - 7.2e-05 22.5 0.1 0.00019 21.1 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CN_hydrolase PF00795.17 KFX98186.1 - 1.5e-22 79.8 0.0 4.2e-22 78.3 0.0 1.6 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase EspB PF05802.6 KFX98186.1 - 0.15 10.9 2.5 0.21 10.5 1.8 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein Mito_carr PF00153.22 KFX98187.1 - 5.2e-56 186.3 2.0 9e-20 70.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Prefoldin_2 PF01920.15 KFX98189.1 - 9.3e-20 70.3 3.7 1.2e-19 70.0 2.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit Atg14 PF10186.4 KFX98189.1 - 0.038 12.9 4.3 1.8 7.4 0.0 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 KFX98189.1 - 0.039 13.8 4.9 0.71 9.7 0.0 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding USP8_interact PF08941.5 KFX98189.1 - 0.045 13.0 0.6 0.045 13.0 0.4 1.6 2 0 0 2 2 2 0 USP8 interacting GM_CSF PF01109.12 KFX98189.1 - 0.096 12.6 1.0 0.23 11.3 0.2 1.7 1 1 1 2 2 2 0 Granulocyte-macrophage colony-stimulating factor Fib_alpha PF08702.5 KFX98189.1 - 0.13 12.3 6.8 2.8 8.0 0.0 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin PF00804.20 KFX98189.1 - 0.14 12.3 6.3 3.3 7.9 4.4 2.0 1 1 0 1 1 1 0 Syntaxin Tropomyosin_1 PF12718.2 KFX98189.1 - 0.16 11.7 4.0 1.3 8.8 0.1 2.1 2 0 0 2 2 2 0 Tropomyosin like Striatin PF08232.7 KFX98189.1 - 0.21 11.9 2.4 7.5 6.8 0.1 2.0 2 0 0 2 2 2 0 Striatin family DUF1640 PF07798.6 KFX98189.1 - 0.29 11.1 5.3 1.4 8.9 3.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Seryl_tRNA_N PF02403.17 KFX98189.1 - 0.33 10.9 5.4 6.8 6.7 1.1 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.6 KFX98189.1 - 0.35 9.4 6.0 4.3 5.8 0.1 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2681 PF10883.3 KFX98189.1 - 0.41 10.8 5.1 7.9 6.7 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) TBPIP PF07106.8 KFX98189.1 - 0.62 9.5 7.7 3.1 7.3 0.1 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) THOC7 PF05615.8 KFX98189.1 - 0.73 10.0 4.2 13 6.0 0.1 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 Tektin PF03148.9 KFX98189.1 - 0.73 8.3 5.8 3 6.2 0.1 2.0 2 0 0 2 2 2 0 Tektin family Uds1 PF15456.1 KFX98189.1 - 0.75 9.7 4.3 4.9 7.1 3.0 1.9 1 1 0 1 1 1 0 Up-regulated During Septation FlxA PF14282.1 KFX98189.1 - 0.87 9.5 13.7 19 5.2 0.0 2.5 2 1 0 2 2 2 0 FlxA-like protein Phage_GP20 PF06810.6 KFX98189.1 - 0.87 9.0 7.4 2.2 7.6 0.3 2.1 1 1 1 2 2 2 0 Phage minor structural protein GP20 OEP PF02321.13 KFX98189.1 - 0.92 9.0 6.3 17 4.9 2.7 2.1 2 0 0 2 2 2 0 Outer membrane efflux protein FliD_C PF07195.7 KFX98189.1 - 1.1 8.5 6.4 27 3.9 4.5 2.0 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus BLOC1_2 PF10046.4 KFX98189.1 - 1.3 9.2 5.7 1.3 9.2 0.1 2.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.7 KFX98189.1 - 1.5 8.6 7.1 6.3 6.5 3.8 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein PspA_IM30 PF04012.7 KFX98189.1 - 1.6 8.0 7.6 3.9 6.7 2.3 2.0 2 0 0 2 2 2 0 PspA/IM30 family TMF_DNA_bd PF12329.3 KFX98189.1 - 2.5 7.9 7.7 1.2 8.9 0.3 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF972 PF06156.8 KFX98189.1 - 2.8 8.3 6.8 1.4e+02 2.8 4.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Proteasome PF00227.21 KFX98193.1 - 8.4e-05 21.9 0.3 0.0001 21.6 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit HCNGP PF07818.8 KFX98194.1 - 6.2e-34 115.9 0.3 1e-33 115.2 0.2 1.3 1 0 0 1 1 1 1 HCNGP-like protein Pkinase PF00069.20 KFX98195.1 - 4e-75 252.3 0.0 6.5e-75 251.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX98195.1 - 7e-37 126.8 0.0 1.1e-36 126.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KFX98195.1 - 3.8e-17 62.1 0.1 8.3e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KFX98195.1 - 1.5e-08 33.9 0.0 6.7e-07 28.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 KFX98195.1 - 0.0032 16.3 0.2 0.0071 15.1 0.0 1.5 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase APH PF01636.18 KFX98195.1 - 0.015 15.0 0.0 0.056 13.1 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KFX98195.1 - 0.029 13.4 0.1 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFX98195.1 - 0.12 11.6 0.6 0.3 10.4 0.2 1.7 1 1 1 2 2 2 0 RIO1 family MDM31_MDM32 PF08118.6 KFX98196.1 - 7.1e-192 638.3 1.1 8.4e-192 638.0 0.8 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins TraH_2 PF06871.6 KFX98196.1 - 0.043 13.2 0.2 0.094 12.1 0.1 1.5 1 0 0 1 1 1 0 TraH_2 KH_1 PF00013.24 KFX98197.1 - 0.00022 20.7 2.1 0.00022 20.7 1.5 1.7 2 0 0 2 2 2 1 KH domain Peptidase_C48 PF02902.14 KFX98198.1 - 4.4e-16 59.1 0.1 1.9e-15 57.0 0.1 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Cation_efflux PF01545.16 KFX98199.1 - 2.4e-31 108.8 7.4 3.1e-31 108.5 5.1 1.1 1 0 0 1 1 1 1 Cation efflux family adh_short PF00106.20 KFX98200.1 - 2.1e-22 79.8 0.2 3.2e-22 79.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX98200.1 - 9.1e-16 58.3 0.0 1.1e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KFX98200.1 - 0.00026 20.2 0.0 0.04 13.0 0.0 2.2 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KFX98200.1 - 0.012 15.6 0.2 0.037 14.0 0.1 1.8 2 0 0 2 2 2 0 NADH(P)-binding ApbA PF02558.11 KFX98200.1 - 0.048 13.1 0.0 0.081 12.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AP_endonuc_2 PF01261.19 KFX98201.1 - 1.9e-26 92.6 0.0 2.7e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel SLX9 PF15341.1 KFX98202.1 - 1.7e-36 125.3 3.5 2.3e-36 124.8 2.4 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 HEPN PF05168.9 KFX98203.1 - 0.028 14.3 0.0 0.07 13.0 0.0 1.6 1 0 0 1 1 1 0 HEPN domain FCH PF00611.18 KFX98203.1 - 0.032 14.4 0.5 0.14 12.3 0.3 2.1 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain DUF4515 PF14988.1 KFX98203.1 - 0.19 11.3 4.5 0.048 13.3 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) AIG2_2 PF13772.1 KFX98204.1 - 7.2e-06 26.0 0.2 4.4e-05 23.5 0.1 2.2 1 1 0 1 1 1 1 AIG2-like family Hormone_3 PF00159.13 KFX98204.1 - 0.14 12.1 0.4 0.14 12.1 0.3 2.1 2 0 0 2 2 2 0 Pancreatic hormone peptide Pkinase PF00069.20 KFX98211.1 - 3.8e-31 108.1 0.0 9.5e-31 106.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX98211.1 - 1.6e-11 43.7 0.0 0.00054 19.1 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.18 KFX98211.1 - 0.001 18.8 0.1 0.058 13.1 0.0 2.8 2 1 0 3 3 3 1 Phosphotransferase enzyme family LETM1 PF07766.8 KFX98226.1 - 8.1e-106 352.9 0.2 1.3e-105 352.2 0.1 1.3 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 KFX98226.1 - 5e-06 25.8 0.2 0.0015 17.9 0.0 3.4 4 0 0 4 4 4 2 SAP domain V_ATPase_I PF01496.14 KFX98226.1 - 0.78 7.5 2.7 11 3.6 2.9 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family SKG6 PF08693.5 KFX98227.1 - 0.002 17.3 0.5 0.002 17.3 0.4 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain PAP1 PF08601.5 KFX98227.1 - 0.017 14.8 11.1 0.022 14.4 7.7 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Pex16 PF08610.5 KFX98227.1 - 0.038 12.9 0.9 0.052 12.5 0.6 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF347 PF03988.7 KFX98227.1 - 0.12 12.3 0.1 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) EVI2A PF05399.6 KFX98227.1 - 0.14 11.4 5.1 0.25 10.5 3.5 1.4 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) TFIIA PF03153.8 KFX98227.1 - 0.28 11.0 6.0 0.34 10.7 4.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1180 PF06679.7 KFX98227.1 - 1.1 9.0 23.1 18 5.1 14.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) Mitofilin PF09731.4 KFX98227.1 - 1.9 7.0 4.4 2.2 6.8 3.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein AJAP1_PANP_C PF15298.1 KFX98227.1 - 3 7.6 20.0 0.84 9.4 10.7 2.1 1 1 1 2 2 2 0 AJAP1/PANP C-terminus hGDE_N PF14699.1 KFX98228.1 - 0.061 13.1 0.1 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme PX PF00787.19 KFX98229.1 - 1.1e-20 73.4 1.3 1.2e-20 73.3 0.1 1.7 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 KFX98229.1 - 7.4e-10 38.4 9.5 7.4e-05 22.1 0.2 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 KFX98229.1 - 0.01 15.3 4.5 0.034 13.6 3.1 1.8 1 1 0 1 1 1 0 BAR domain DUF3140 PF11338.3 KFX98229.1 - 0.061 13.4 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3140) Occludin_ELL PF07303.8 KFX98229.1 - 0.092 13.4 0.6 9.3 7.0 0.0 2.9 3 0 0 3 3 3 0 Occludin homology domain FlaC_arch PF05377.6 KFX98229.1 - 0.92 9.4 3.9 1.2 9.0 0.1 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HAD PF12710.2 KFX98230.1 - 5.5e-13 49.5 0.0 1.3e-12 48.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFX98230.1 - 1.3e-12 47.3 1.1 2e-11 43.3 0.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KFX98230.1 - 1.4e-12 47.3 0.0 5.7e-12 45.4 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 KFX98230.1 - 5e-12 46.6 1.7 1.6e-10 41.7 1.2 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFX98230.1 - 0.0087 15.6 0.3 0.026 14.1 0.2 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase IDO PF01231.13 KFX98259.1 - 1e-68 231.7 0.0 1.2e-68 231.5 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase GCN5L1 PF06320.8 KFX98261.1 - 1.9e-05 24.4 0.1 5.7e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 GCN5-like protein 1 (GCN5L1) PHD PF00628.24 KFX98261.1 - 0.0055 16.3 6.8 0.011 15.4 4.7 1.5 1 0 0 1 1 1 1 PHD-finger DOCK-C2 PF14429.1 KFX98262.1 - 6.3e-28 97.6 0.0 1.2e-27 96.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 KFX98262.1 - 5.4e-10 38.8 0.1 1.7e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 KFX98262.1 - 0.0002 20.7 0.0 0.0004 19.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFX98262.1 - 0.00088 18.8 0.0 0.0063 16.0 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain ADH_N PF08240.7 KFX98263.1 - 2.2e-09 37.0 0.0 6.1e-09 35.6 0.0 1.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFX98263.1 - 2.9e-06 28.2 0.0 1.7e-05 25.7 0.0 2.2 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KFX98263.1 - 0.015 14.8 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Biotin_lipoyl PF00364.17 KFX98263.1 - 0.02 14.4 1.4 0.63 9.7 0.0 2.6 3 0 0 3 3 3 0 Biotin-requiring enzyme APH PF01636.18 KFX98267.1 - 0.00059 19.6 0.1 0.0011 18.7 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KFX98267.1 - 0.0021 17.2 0.2 0.0031 16.7 0.1 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 KFX98267.1 - 0.0032 17.0 0.1 0.0051 16.4 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase QLQ PF08880.6 KFX98267.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 QLQ Zn_clus PF00172.13 KFX98268.1 - 0.00081 19.2 10.4 0.00081 19.2 7.2 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 KFX98268.1 - 0.0048 17.1 2.8 0.0048 17.1 2.0 2.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX98268.1 - 0.023 15.0 1.0 0.023 15.0 0.7 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger ABC2_membrane PF01061.19 KFX98269.1 - 3.3e-74 248.6 52.3 2.3e-41 141.2 11.0 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 KFX98269.1 - 1.1e-28 100.1 0.0 1.4e-13 51.2 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 KFX98269.1 - 1.3e-17 63.2 1.8 9e-17 60.6 0.0 3.1 3 0 0 3 3 2 1 CDR ABC transporter AAA_25 PF13481.1 KFX98269.1 - 1.2e-05 24.8 0.5 0.013 14.8 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.1 KFX98269.1 - 5.4e-05 23.3 0.2 5.4e-05 23.3 0.1 2.5 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.1 KFX98269.1 - 0.00015 21.6 0.3 0.0098 15.7 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KFX98269.1 - 0.00016 21.1 3.2 0.024 14.1 0.1 3.9 4 0 0 4 4 4 1 P-loop containing region of AAA domain SMC_N PF02463.14 KFX98269.1 - 0.00043 19.5 0.2 0.12 11.5 0.0 3.5 4 1 0 4 4 3 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 KFX98269.1 - 0.00079 19.4 0.2 0.0055 16.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KFX98269.1 - 0.0012 18.0 0.3 0.0042 16.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KFX98269.1 - 0.0018 18.3 1.1 0.13 12.3 0.1 3.5 3 2 1 4 4 4 1 AAA domain AAA_17 PF13207.1 KFX98269.1 - 0.012 16.4 0.0 0.094 13.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KFX98269.1 - 0.021 15.1 0.0 0.22 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KFX98269.1 - 0.024 15.1 0.0 0.54 10.7 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein UPF0079 PF02367.12 KFX98269.1 - 0.03 13.9 0.9 0.14 11.7 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 KFX98269.1 - 0.031 14.2 0.1 0.78 9.7 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.7 KFX98269.1 - 0.035 13.7 0.1 0.35 10.4 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 KFX98269.1 - 0.043 13.7 2.9 0.48 10.3 0.4 2.9 2 1 1 3 3 3 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KFX98269.1 - 0.045 13.2 0.2 7.4 5.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_15 PF13175.1 KFX98269.1 - 0.074 12.0 0.0 0.67 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 KFX98269.1 - 0.1 12.8 0.2 0.27 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KFX98269.1 - 0.13 11.3 0.2 1.9 7.5 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.17 KFX98269.1 - 0.17 10.7 0.8 2 7.2 0.1 2.6 3 0 0 3 3 3 0 NB-ARC domain NTPase_1 PF03266.10 KFX98269.1 - 0.31 10.7 0.2 18 4.9 0.1 3.0 3 0 0 3 3 3 0 NTPase cobW PF02492.14 KFX98269.1 - 0.96 8.8 2.4 1.2 8.5 0.3 2.1 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain DIOX_N PF14226.1 KFX98270.1 - 1.4e-21 77.1 0.2 2.4e-21 76.4 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KFX98270.1 - 1.1e-14 54.4 0.0 1.8e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily COX7a PF02238.10 KFX98270.1 - 0.12 12.1 0.1 0.54 10.0 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIa AMP-binding PF00501.23 KFX98271.1 - 8.1e-64 215.5 0.0 9.6e-64 215.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX98271.1 - 2.3e-07 31.6 0.0 1.1e-06 29.4 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DUF946 PF06101.6 KFX98271.1 - 0.091 10.7 0.0 0.13 10.2 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF946) DAHP_synth_2 PF01474.11 KFX98272.1 - 1.7e-124 415.5 0.0 8.9e-72 241.8 0.0 2.0 1 1 1 2 2 2 2 Class-II DAHP synthetase family Methyltransf_23 PF13489.1 KFX98274.1 - 9.4e-12 44.9 0.0 1.5e-11 44.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX98274.1 - 4.5e-08 32.8 0.0 3.3e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX98274.1 - 3.1e-05 24.3 0.0 6.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX98274.1 - 8.7e-05 22.9 0.0 0.00033 21.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX98274.1 - 0.012 16.1 0.1 0.12 13.0 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 KFX98274.1 - 0.014 14.6 0.0 0.061 12.6 0.0 1.9 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.13 KFX98274.1 - 0.13 11.3 0.0 0.29 10.2 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family ApoLp-III PF07464.6 KFX98279.1 - 0.047 13.7 3.1 0.065 13.2 2.1 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.8 KFX98279.1 - 0.13 12.6 5.2 4.3 7.8 2.2 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) ISG65-75 PF11727.3 KFX98279.1 - 0.65 8.9 8.7 1.2 8.1 6.0 1.5 1 1 0 1 1 1 0 Invariant surface glycoprotein CsbD PF05532.7 KFX98279.1 - 1.8 8.3 19.9 1.9 8.1 9.2 3.8 2 2 0 2 2 2 0 CsbD-like MRG PF05712.8 KFX98281.1 - 1e-49 168.0 0.0 1.6e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 KFX98281.1 - 4.1e-08 32.8 1.5 9.4e-08 31.6 1.0 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 KFX98281.1 - 0.0007 19.2 1.0 0.0019 17.8 0.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RabGAP-TBC PF00566.13 KFX98283.1 - 3.3e-27 95.3 0.0 5.4e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Glyco_hydro_7 PF00840.15 KFX98284.1 - 1.2e-203 676.3 23.7 1.4e-203 676.1 16.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_21 PF03370.8 KFX98287.1 - 6.6e-34 116.2 3.2 1.2e-33 115.3 2.2 1.5 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Acyltransferase PF01553.16 KFX98288.1 - 2.3e-32 111.1 0.0 4.3e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase SNO PF01174.14 KFX98290.1 - 1.3e-54 184.7 0.0 7e-45 152.9 0.0 2.0 1 1 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 KFX98290.1 - 7.6e-10 38.6 0.0 8.2e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 KFX98290.1 - 9.2e-05 21.9 0.0 0.092 12.1 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 KFX98290.1 - 0.0011 18.5 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KFX98290.1 - 0.0014 17.9 0.1 0.0026 17.0 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase PX PF00787.19 KFX98291.1 - 1.2e-18 66.9 0.0 3.2e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 KFX98291.1 - 4.7e-15 55.4 5.1 5.6e-09 35.6 0.3 2.2 2 0 0 2 2 2 2 Vps5 C terminal like DUF1675 PF07897.6 KFX98291.1 - 0.32 10.8 5.4 0.062 13.1 1.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) Acyltransferase PF01553.16 KFX98292.1 - 6.8e-12 44.9 0.0 5.3e-11 42.0 0.0 2.3 2 1 0 2 2 2 1 Acyltransferase Abhydrolase_5 PF12695.2 KFX98295.1 - 4e-06 26.6 0.0 6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX98295.1 - 8.2e-06 25.8 0.1 1.1e-05 25.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFX98295.1 - 0.0064 15.7 0.0 0.56 9.3 0.0 2.1 1 1 0 2 2 2 2 Prolyl oligopeptidase family QRPTase_C PF01729.14 KFX98300.1 - 5.9e-35 120.2 0.0 6.6e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain PRAI PF00697.17 KFX98300.1 - 0.00073 19.1 0.0 0.00085 18.9 0.0 1.1 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF1341 PF07071.6 KFX98300.1 - 0.033 13.7 0.0 0.053 13.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1341) FMN_dh PF01070.13 KFX98300.1 - 0.08 11.7 0.1 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase ADH_N PF08240.7 KFX98301.1 - 4.1e-11 42.6 0.0 8.5e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX98301.1 - 1.1e-07 31.4 1.4 2.5e-07 30.2 1.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 KFX98301.1 - 0.13 12.0 1.6 0.25 11.1 0.4 1.9 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3237 PF11578.3 KFX98302.1 - 9e-23 80.2 0.0 1.3e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) DUF4470 PF14737.1 KFX98303.1 - 5.1e-21 74.2 0.1 1.2e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) POP1 PF06978.6 KFX98304.1 - 2.2e-59 200.2 6.2 2.2e-59 200.2 4.3 1.7 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 KFX98304.1 - 6.8e-29 99.5 0.3 1.8e-28 98.2 0.2 1.8 1 0 0 1 1 1 1 POPLD (NUC188) domain SLD3 PF08639.5 KFX98304.1 - 0.4 9.2 6.1 0.89 8.1 4.2 1.5 1 0 0 1 1 1 0 DNA replication regulator SLD3 Adeno_terminal PF02459.10 KFX98304.1 - 0.43 8.6 5.7 0.64 8.1 4.0 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Redoxin PF08534.5 KFX98305.1 - 6.8e-34 116.5 0.0 7.7e-34 116.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KFX98305.1 - 1.1e-13 50.9 0.0 1.4e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1348 PF07080.6 KFX98306.1 - 6.4e-57 191.3 4.0 7.7e-57 191.1 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 KFX98306.1 - 2.2e-08 34.4 1.4 3e-08 33.9 1.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 KFX98306.1 - 7e-06 26.2 0.2 9.8e-06 25.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF4398 PF14346.1 KFX98306.1 - 0.044 13.8 0.0 0.069 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) Y_phosphatase3 PF13350.1 KFX98307.1 - 1.6e-42 145.5 0.0 2.6e-42 144.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KFX98307.1 - 6e-08 32.6 0.0 1.5e-06 28.2 0.0 2.4 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 KFX98307.1 - 0.048 12.9 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 KFX98307.1 - 0.051 12.9 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFX98307.1 - 0.097 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Glyco_hydro_3 PF00933.16 KFX98308.1 - 1.4e-91 306.6 0.0 2e-91 306.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFX98308.1 - 1.4e-56 191.5 0.3 6.3e-56 189.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFX98308.1 - 2e-21 75.6 0.0 4.7e-21 74.5 0.0 1.7 1 1 0 1 1 1 1 Fibronectin type III-like domain PIRT PF15099.1 KFX98308.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Dala_Dala_lig_C PF07478.8 KFX98309.1 - 3.5e-27 95.1 0.0 5.7e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Glyco_hydro_16 PF00722.16 KFX98309.1 - 3.4e-08 32.9 1.4 6.4e-08 32.0 0.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 ATP-grasp_4 PF13535.1 KFX98309.1 - 1.2e-07 31.6 0.0 2.1e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KFX98309.1 - 0.0004 20.2 0.0 0.00081 19.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KFX98309.1 - 0.0029 16.9 0.0 0.0083 15.4 0.0 1.7 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.14 KFX98309.1 - 0.0032 17.0 0.0 0.006 16.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.1 KFX98309.1 - 0.011 14.5 0.0 0.18 10.5 0.0 2.5 2 1 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_N PF01820.16 KFX98309.1 - 0.022 15.0 0.0 0.04 14.2 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus DUF2235 PF09994.4 KFX98310.1 - 2.3e-76 256.8 0.2 3.5e-76 256.2 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KFX98310.1 - 0.0093 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.3 KFX98310.1 - 0.062 12.4 0.0 0.15 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) An_peroxidase PF03098.10 KFX98311.1 - 8.1e-77 258.7 0.0 1.6e-58 198.4 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.17 KFX98311.1 - 9.1e-10 37.6 0.1 4.3e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Cellulase PF00150.13 KFX98313.1 - 2.8e-56 190.8 0.1 3.5e-56 190.4 0.1 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cytomega_UL20A PF05984.7 KFX98313.1 - 0.16 12.2 0.0 0.39 10.9 0.0 1.6 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein RGS PF00615.14 KFX98314.1 - 5.5e-09 36.1 0.0 4.2e-06 26.8 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain MPC PF03650.8 KFX98315.1 - 1.6e-41 141.0 0.6 2.1e-41 140.6 0.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) L51_S25_CI-B8 PF05047.11 KFX98316.1 - 4.3e-13 48.7 0.0 5.4e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain EAF PF09816.4 KFX98317.1 - 2.2e-05 24.3 0.0 5.6e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase II transcription elongation factor FAD_binding_7 PF03441.9 KFX98318.1 - 1.4e-48 165.5 0.1 1.9e-48 165.1 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KFX98318.1 - 2.4e-20 72.9 0.0 3.8e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase GshA PF08886.6 KFX98318.1 - 0.29 9.3 0.0 0.42 8.8 0.0 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase 4HBT PF03061.17 KFX98319.1 - 2.6e-07 30.6 0.1 5.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily MmgE_PrpD PF03972.9 KFX98322.1 - 7.5e-149 495.6 0.0 9e-149 495.4 0.0 1.1 1 0 0 1 1 1 1 MmgE/PrpD family Sulf_transp PF04143.9 KFX98324.1 - 8.6e-15 54.4 29.1 8.9e-12 44.8 6.8 5.3 5 1 1 6 6 6 2 Sulphur transport DUF4341 PF14241.1 KFX98324.1 - 0.0015 18.1 3.0 0.0015 18.1 2.0 4.8 5 1 0 5 5 5 1 Domain of unknown function (DUF4341) Fungal_trans PF04082.13 KFX98325.1 - 3e-27 95.1 0.0 4.4e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX98325.1 - 3.5e-05 23.6 13.1 7.3e-05 22.5 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain R3H PF01424.17 KFX98327.1 - 1.6e-10 40.5 0.1 2.9e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 KFX98327.1 - 2.4e-09 37.0 0.0 4.4e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFX98327.1 - 3.8e-06 26.4 0.0 1.1e-05 24.9 0.0 1.8 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX98327.1 - 0.0002 21.1 0.0 0.00037 20.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.7 KFX98327.1 - 0.18 11.8 0.0 0.36 10.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif 2 Na_H_Exchanger PF00999.16 KFX98328.1 - 3.5e-19 68.5 1.8 7.7e-19 67.4 0.1 2.0 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family YrhC PF14143.1 KFX98328.1 - 0.011 15.7 0.0 0.027 14.3 0.0 1.7 1 0 0 1 1 1 0 YrhC-like protein OPT PF03169.10 KFX98330.1 - 6.4e-174 579.8 57.6 7.3e-174 579.6 39.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DAO PF01266.19 KFX98331.1 - 1.8e-43 148.8 0.0 2.2e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFX98331.1 - 2.1e-05 24.4 0.0 0.07 12.9 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX98331.1 - 0.00021 21.2 0.0 0.00074 19.4 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KFX98331.1 - 0.00092 18.1 0.1 0.43 9.3 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KFX98331.1 - 0.0015 17.4 0.0 0.07 11.9 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 KFX98331.1 - 0.0046 17.0 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KFX98331.1 - 0.0055 16.5 0.0 0.0099 15.6 0.0 1.4 1 0 0 1 1 1 1 ThiF family FAD_binding_3 PF01494.14 KFX98331.1 - 0.0071 15.4 0.0 0.024 13.6 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 KFX98331.1 - 0.0085 15.8 0.1 0.059 13.1 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KFX98331.1 - 0.017 15.5 0.0 0.16 12.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KFX98331.1 - 0.037 14.2 0.0 0.086 13.1 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 KFX98331.1 - 0.07 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Trp_halogenase PF04820.9 KFX98331.1 - 0.13 10.9 0.1 1.2 7.6 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase DAO PF01266.19 KFX98332.1 - 2.7e-51 174.5 0.0 3.8e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fungal_trans_2 PF11951.3 KFX98332.1 - 2.9e-50 170.9 7.1 8.6e-25 87.1 3.6 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX98332.1 - 1.1e-06 28.3 8.4 2.1e-06 27.5 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_8 PF13450.1 KFX98332.1 - 1.6e-06 28.0 0.0 3.6e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFX98332.1 - 6.3e-05 22.0 0.1 0.0015 17.4 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KFX98332.1 - 0.00029 20.7 0.0 0.035 13.9 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFX98332.1 - 0.012 14.6 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.16 KFX98332.1 - 0.015 15.0 0.0 0.034 13.9 0.0 1.6 1 0 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.1 KFX98332.1 - 0.017 15.1 0.0 0.29 11.1 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KFX98332.1 - 0.065 11.8 0.0 7.5 5.0 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KFX98332.1 - 0.075 12.8 0.1 0.67 9.7 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 KFX98332.1 - 0.091 13.1 0.0 0.56 10.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 KFX98332.1 - 0.15 11.7 0.0 0.53 9.9 0.0 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Metallophos PF00149.23 KFX98336.1 - 1.2e-44 152.0 0.2 1.5e-44 151.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MT-A70 PF05063.9 KFX98339.1 - 4.9e-26 91.3 0.0 5.3e-18 65.1 0.0 2.3 2 0 0 2 2 2 2 MT-A70 Ribosomal_L23 PF00276.15 KFX98340.1 - 7.4e-14 51.4 0.1 1.5e-13 50.5 0.1 1.5 1 1 0 1 1 1 1 Ribosomal protein L23 Lipoprotein_X PF03305.8 KFX98340.1 - 0.059 12.7 0.1 0.078 12.3 0.1 1.2 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein Pex2_Pex12 PF04757.9 KFX98341.1 - 7.9e-56 189.0 3.0 1e-55 188.6 2.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 KFX98341.1 - 9e-06 25.6 2.6 1.6e-05 24.8 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFX98341.1 - 6.3e-05 22.7 2.7 0.00011 21.9 1.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KFX98341.1 - 0.0022 17.8 1.9 0.0034 17.1 1.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFX98341.1 - 0.012 15.2 2.9 0.02 14.5 2.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFX98341.1 - 0.042 13.5 1.4 0.065 12.9 1.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFX98341.1 - 0.05 13.3 0.2 0.05 13.3 0.2 1.9 2 0 0 2 2 2 0 RING-type zinc-finger Hamartin PF04388.7 KFX98342.1 - 8.2e-44 150.3 10.3 8.2e-44 150.3 7.1 2.2 1 1 1 2 2 2 1 Hamartin protein Kdo PF06293.9 KFX98345.1 - 0.00022 20.3 0.2 0.0016 17.5 0.1 1.9 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFX98345.1 - 0.016 14.5 0.1 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.15 KFX98345.1 - 0.027 13.6 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase WaaY PF06176.6 KFX98345.1 - 0.042 13.0 0.0 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase PF00069.20 KFX98345.1 - 0.11 11.6 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein kinase domain CPSase_L_D2 PF02786.12 KFX98346.1 - 1.2e-112 374.3 0.2 2e-84 282.1 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 KFX98346.1 - 3.8e-44 150.4 0.0 7.9e-44 149.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 KFX98346.1 - 5.1e-44 148.9 0.0 1.1e-43 147.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.14 KFX98346.1 - 2.4e-42 143.5 0.1 6.2e-42 142.2 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace_N PF02729.16 KFX98346.1 - 1.4e-41 141.5 0.0 2.8e-41 140.4 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 KFX98346.1 - 4.9e-39 132.8 0.0 3.8e-19 68.8 0.0 3.1 3 0 0 3 3 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 KFX98346.1 - 3e-34 118.3 0.5 3.3e-20 72.6 0.0 3.2 3 0 0 3 3 3 2 ATP-grasp domain OTCace PF00185.19 KFX98346.1 - 1.3e-33 116.1 0.0 3.1e-33 114.8 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.17 KFX98346.1 - 8.6e-22 76.8 0.0 1e-20 73.4 0.0 2.8 2 0 0 2 2 2 1 MGS-like domain ATPgrasp_Ter PF15632.1 KFX98346.1 - 2.8e-19 69.0 0.1 2.5e-09 36.3 0.0 4.0 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KFX98346.1 - 5.4e-15 55.3 0.4 9.8e-07 28.3 0.1 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KFX98346.1 - 9.3e-15 54.3 0.1 1.8e-06 27.3 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 KFX98346.1 - 2.4e-06 27.1 0.5 8e-05 22.1 0.4 2.5 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 KFX98346.1 - 1.9e-05 24.6 0.4 0.17 11.7 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 KFX98346.1 - 0.0019 17.7 0.3 1.7 8.1 0.0 2.9 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DJ-1_PfpI PF01965.19 KFX98346.1 - 0.0055 16.1 0.0 0.016 14.6 0.0 1.7 1 0 0 1 1 1 1 DJ-1/PfpI family Ribonuclease_3 PF00636.21 KFX98347.1 - 3.9e-40 136.8 0.0 9.4e-19 67.9 0.0 2.9 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.9 KFX98347.1 - 8.6e-23 79.9 0.2 5.2e-21 74.2 0.0 2.9 3 0 0 3 3 3 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.1 KFX98347.1 - 6e-22 77.9 0.0 7.6e-10 38.8 0.0 3.6 3 0 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.26 KFX98347.1 - 2.6e-15 56.0 0.1 7.5e-15 54.5 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFX98347.1 - 4.7e-11 42.8 0.0 1.2e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFX98347.1 - 6.5e-11 42.0 0.0 1.4e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.20 KFX98347.1 - 0.0024 18.4 0.0 1.5 9.4 0.0 2.9 2 0 0 2 2 2 1 Double-stranded RNA binding motif DUF2075 PF09848.4 KFX98347.1 - 0.089 11.7 0.0 0.2 10.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TAP42 PF04177.7 KFX98348.1 - 5.4e-97 324.7 0.0 6e-97 324.6 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family Glyoxalase PF00903.20 KFX98349.1 - 6.1e-08 32.6 0.3 8.2e-08 32.2 0.2 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KFX98349.1 - 6.1e-05 22.9 0.2 0.0001 22.2 0.1 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KFX98349.1 - 0.0002 21.9 0.2 0.00027 21.4 0.1 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain TOM_sub5 PF15178.1 KFX98349.1 - 0.082 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM5 homolog FAD_binding_3 PF01494.14 KFX98350.1 - 1.5e-23 83.4 0.0 8e-23 81.0 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFX98350.1 - 4.3e-14 52.2 2.7 1.1e-06 27.8 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFX98350.1 - 4e-08 32.5 0.4 1.4e-06 27.4 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KFX98350.1 - 5.8e-08 32.8 0.1 1.7e-07 31.3 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX98350.1 - 6.5e-08 32.8 0.3 0.01 16.2 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KFX98350.1 - 1.4e-06 27.6 0.1 2.6e-06 26.7 0.1 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFX98350.1 - 1.2e-05 24.0 0.9 0.00011 20.8 0.6 2.1 1 1 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 KFX98350.1 - 0.00013 21.9 0.3 0.00032 20.6 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KFX98350.1 - 0.00075 18.2 1.2 0.014 14.0 0.1 2.5 2 1 0 3 3 3 1 Tryptophan halogenase GIDA PF01134.17 KFX98350.1 - 0.0021 16.9 0.9 0.0031 16.4 0.7 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 KFX98350.1 - 0.0057 15.7 0.2 0.0095 15.0 0.1 1.2 1 0 0 1 1 1 1 Thi4 family SE PF08491.5 KFX98350.1 - 0.025 13.4 0.0 0.16 10.7 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_3 PF13738.1 KFX98350.1 - 0.037 14.0 0.0 0.1 12.6 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KFX98350.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KFX98350.1 - 0.11 11.3 0.1 0.44 9.3 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Ank_2 PF12796.2 KFX98351.1 - 1.2e-29 102.4 0.3 7.2e-15 55.0 0.0 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFX98351.1 - 7.3e-22 77.3 0.3 6.5e-10 39.2 0.0 3.4 3 1 1 4 4 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KFX98351.1 - 3.3e-21 73.9 0.9 6e-09 35.2 0.0 5.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 KFX98351.1 - 1.2e-19 69.8 0.3 8.9e-10 38.4 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX98351.1 - 4.5e-17 60.4 0.6 2.6e-05 24.0 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat NACHT PF05729.7 KFX98351.1 - 3.2e-11 43.1 0.3 0.0085 15.7 0.0 3.9 3 1 0 3 3 3 3 NACHT domain RNA_helicase PF00910.17 KFX98351.1 - 5.7e-07 29.6 0.2 0.011 15.9 0.0 3.0 3 0 0 3 3 3 2 RNA helicase AAA_22 PF13401.1 KFX98351.1 - 8.3e-06 25.9 0.2 0.0013 18.8 0.0 3.7 3 1 0 3 3 3 1 AAA domain Abhydrolase_6 PF12697.2 KFX98351.1 - 2.9e-05 24.0 0.0 5.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX98351.1 - 8.7e-05 22.3 0.1 0.00025 20.8 0.0 1.7 2 0 0 2 2 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KFX98351.1 - 0.00016 21.0 0.0 0.00036 19.8 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA PF00004.24 KFX98351.1 - 0.00025 21.2 0.0 0.7 10.0 0.0 3.9 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KFX98351.1 - 0.0005 19.9 0.0 0.0024 17.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFX98351.1 - 0.00087 19.3 0.1 0.24 11.3 0.1 3.4 2 1 0 2 2 2 1 AAA ATPase domain APS_kinase PF01583.15 KFX98351.1 - 0.001 18.7 0.0 0.079 12.6 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_17 PF13207.1 KFX98351.1 - 0.0021 18.8 0.4 0.077 13.8 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFX98351.1 - 0.0041 17.4 0.2 0.033 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 KFX98351.1 - 0.014 15.7 0.0 0.084 13.1 0.0 2.2 2 0 0 2 2 2 0 ABC transporter PGAP1 PF07819.8 KFX98351.1 - 0.02 14.4 0.0 0.093 12.3 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein NB-ARC PF00931.17 KFX98351.1 - 0.029 13.2 0.0 0.25 10.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain UPF0079 PF02367.12 KFX98351.1 - 0.038 13.6 0.0 0.85 9.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 KFX98351.1 - 0.043 13.0 0.1 0.24 10.5 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 KAP_NTPase PF07693.9 KFX98351.1 - 0.061 12.2 0.3 0.26 10.2 0.0 2.0 1 1 1 2 2 2 0 KAP family P-loop domain NTPase_1 PF03266.10 KFX98351.1 - 0.095 12.3 0.1 0.71 9.5 0.0 2.4 3 0 0 3 3 3 0 NTPase PaaSYMP PF14738.1 KFX98351.1 - 0.17 11.5 1.9 0.19 11.4 0.1 1.9 2 0 0 2 2 2 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 STE3 PF02076.10 KFX98366.1 - 1.4e-14 53.8 0.7 1.8e-14 53.5 0.5 1.1 1 0 0 1 1 1 1 Pheromone A receptor PAPS_reduct PF01507.14 KFX98367.1 - 3.1e-22 79.2 0.0 7.4e-20 71.4 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family DUF202 PF02656.10 KFX98368.1 - 1.8e-19 69.7 1.4 8.9e-19 67.4 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF202) 2TM PF13239.1 KFX98368.1 - 0.027 14.5 1.0 0.056 13.5 0.1 1.9 1 1 1 2 2 2 0 2TM domain COX4_pro_2 PF07835.7 KFX98368.1 - 0.028 14.3 1.1 0.31 11.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV PGG PF13962.1 KFX98368.1 - 0.077 12.6 0.4 0.78 9.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function MatE PF01554.13 KFX98369.1 - 1.4e-53 180.8 28.4 5.9e-27 94.2 7.1 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 KFX98369.1 - 4.7e-05 23.2 4.1 4.7e-05 23.2 2.9 3.9 4 2 0 4 4 4 1 Polysaccharide biosynthesis C-terminal domain MFS_1 PF07690.11 KFX98370.1 - 2.1e-19 69.4 20.3 2.6e-19 69.1 14.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4500 PF14937.1 KFX98370.1 - 0.015 15.1 0.2 0.034 13.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) DUF2417 PF10329.4 KFX98370.1 - 0.24 10.7 4.0 2.9 7.2 1.3 3.0 3 0 0 3 3 3 0 Region of unknown function (DUF2417) DUF2389 PF09493.5 KFX98370.1 - 2.7 8.3 5.3 14 6.0 0.2 3.7 4 0 0 4 4 4 0 Tryptophan-rich protein (DUF2389) Sulfatase PF00884.18 KFX98371.1 - 2.3e-43 148.5 0.0 1.5e-41 142.6 0.0 2.5 1 1 0 1 1 1 1 Sulfatase CDC45 PF02724.9 KFX98371.1 - 0.018 13.0 6.8 0.03 12.3 4.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KFX98371.1 - 2.8 5.7 13.5 3.9 5.2 9.4 1.1 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.2 KFX98371.1 - 3.8 5.0 5.2 5.6 4.5 3.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Beta-lactamase PF00144.19 KFX98372.1 - 8.5e-32 110.4 0.8 2.2e-31 109.1 0.6 1.5 1 1 0 1 1 1 1 Beta-lactamase APH PF01636.18 KFX98373.1 - 7e-07 29.2 0.0 2.2e-05 24.3 0.0 2.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX98373.1 - 0.01 15.3 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Peptidase_M49 PF03571.10 KFX98374.1 - 1.2e-194 647.4 0.0 1.4e-194 647.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 2C_adapt PF08793.5 KFX98374.1 - 0.087 12.7 0.4 0.96 9.3 0.2 2.4 2 0 0 2 2 2 0 2-cysteine adaptor domain TPR_12 PF13424.1 KFX98376.1 - 4.5e-25 87.3 9.2 2.7e-11 43.2 0.0 5.3 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 KFX98376.1 - 1.5e-14 53.3 4.1 0.0013 18.5 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFX98376.1 - 5e-11 41.6 3.6 0.027 14.3 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFX98376.1 - 6.2e-11 41.7 10.6 5.1e-07 29.2 0.1 5.2 4 2 1 5 5 5 2 TPR repeat TPR_1 PF00515.23 KFX98376.1 - 1.2e-09 37.4 0.5 9.4e-05 21.8 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFX98376.1 - 3.2e-07 30.3 6.7 1.1 10.0 0.1 6.6 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFX98376.1 - 9.7e-06 25.0 2.7 0.06 13.1 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFX98376.1 - 1.2e-05 24.6 0.0 0.073 12.9 0.0 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat PPR PF01535.15 KFX98376.1 - 9.9e-05 22.0 0.1 0.4 10.7 0.0 4.1 5 0 0 5 5 5 1 PPR repeat TPR_19 PF14559.1 KFX98376.1 - 0.00014 22.0 5.1 1.3 9.3 0.0 5.0 2 1 4 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFX98376.1 - 0.0057 17.3 12.0 4 8.2 0.0 5.3 2 1 5 7 7 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 KFX98376.1 - 0.015 15.6 0.9 2.6 8.7 0.1 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 KFX98376.1 - 0.11 12.6 3.0 12 6.3 0.0 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat NAGidase PF07555.8 KFX98377.1 - 5.2e-100 334.3 0.2 8.7e-100 333.5 0.1 1.3 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase Glyco_hydro_20b PF02838.10 KFX98377.1 - 7.5e-19 68.4 0.1 1.5e-18 67.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_67N PF03648.9 KFX98377.1 - 4.3e-05 23.5 0.1 0.00012 22.0 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 67 N-terminus Arb1 PF09692.5 KFX98378.1 - 5.3e-120 400.9 0.0 6.4e-120 400.6 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 IPK PF03770.11 KFX98379.1 - 6.4e-54 182.5 0.0 7.8e-54 182.3 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase ADH_zinc_N PF00107.21 KFX98398.1 - 1.7e-25 89.0 2.0 3.5e-25 88.0 1.4 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX98398.1 - 1.1e-17 63.7 1.0 2.1e-17 62.8 0.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KFX98398.1 - 5.2e-05 24.1 0.5 5.2e-05 24.1 0.4 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Sod_Fe_C PF02777.13 KFX98399.1 - 8.4e-12 44.8 0.0 5.1e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Aminotran_5 PF00266.14 KFX98400.1 - 9e-26 90.4 0.0 2.1e-25 89.2 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V MOSC PF03473.12 KFX98400.1 - 1.5e-21 76.2 0.0 2.9e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 KFX98400.1 - 2.1e-19 69.4 0.0 4.7e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain NAD_binding_8 PF13450.1 KFX98403.1 - 0.0024 17.8 0.1 0.0083 16.1 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFX98403.1 - 0.004 16.1 0.4 0.007 15.3 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KFX98403.1 - 0.056 12.0 0.2 0.075 11.6 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Mito_carr PF00153.22 KFX98406.1 - 3.5e-60 199.7 4.5 7.2e-21 73.7 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Sec34 PF04136.10 KFX98406.1 - 1.1e-29 103.1 1.4 2.2e-29 102.1 0.9 1.4 1 0 0 1 1 1 1 Sec34-like family RCC1 PF00415.13 KFX98407.1 - 2.9e-26 91.4 10.1 9.8e-05 22.4 0.0 8.1 7 2 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFX98407.1 - 4.9e-10 38.7 19.9 4.4e-07 29.3 0.2 6.2 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat CAF-1_p150 PF11600.3 KFX98408.1 - 0.012 14.9 33.8 0.017 14.4 23.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CRT10 PF08728.5 KFX98408.1 - 0.5 8.2 10.8 0.58 8.0 7.5 1.0 1 0 0 1 1 1 0 CRT10 Borrelia_P83 PF05262.6 KFX98408.1 - 0.61 8.2 21.0 0.75 7.9 14.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF1510 PF07423.6 KFX98408.1 - 1.2 8.5 25.9 1.6 8.0 18.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Toxin_25 PF08095.6 KFX98408.1 - 1.5 8.5 4.4 1.9 8.3 0.2 2.6 2 0 0 2 2 2 0 Hefutoxin family PPP4R2 PF09184.6 KFX98408.1 - 1.6 8.1 17.4 35 3.8 12.0 2.0 2 0 0 2 2 2 0 PPP4R2 Zip PF02535.17 KFX98408.1 - 1.7 7.5 7.9 2.5 7.0 5.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.12 KFX98408.1 - 2.3 7.9 14.4 3.8 7.2 10.0 1.4 1 0 0 1 1 1 0 DDHD domain Hom_end_hint PF05203.11 KFX98408.1 - 3.3 7.3 10.1 4.6 6.9 7.0 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint LMBR1 PF04791.11 KFX98408.1 - 3.8 5.9 7.7 4.3 5.8 5.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein VIT1 PF01988.14 KFX98408.1 - 4.2 6.7 4.5 7.7 5.9 3.1 1.5 1 0 0 1 1 1 0 VIT family eIF-3_zeta PF05091.7 KFX98408.1 - 4.3 5.8 21.6 5.7 5.4 15.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.7 KFX98408.1 - 4.7 7.0 18.6 7.9 6.2 12.9 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SOBP PF15279.1 KFX98408.1 - 5.6 7.2 13.2 7.5 6.8 9.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Neur_chan_memb PF02932.11 KFX98408.1 - 7.8 6.2 11.6 11 5.7 8.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DEAD PF00270.24 KFX98410.1 - 1.2e-42 145.2 0.0 1.8e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX98410.1 - 6.8e-24 83.5 0.1 1.8e-23 82.1 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CoA_trans PF01144.18 KFX98411.1 - 2.4e-99 330.9 2.1 1.3e-61 207.5 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase Nrap PF03813.9 KFX98412.1 - 0 1123.0 0.0 0 1122.8 0.0 1.0 1 0 0 1 1 1 1 Nrap protein Cys_Met_Meta_PP PF01053.15 KFX98413.1 - 7.8e-29 100.1 0.0 1.3e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SMC_N PF02463.14 KFX98413.1 - 3e-24 85.5 0.9 5e-24 84.7 0.6 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KFX98413.1 - 2e-07 31.5 46.5 2e-07 31.5 32.3 5.3 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 KFX98413.1 - 1.8e-06 28.1 0.5 2.4e-05 24.4 0.4 2.4 2 0 0 2 2 2 1 AAA domain SMC_hinge PF06470.8 KFX98413.1 - 0.00018 21.4 0.0 0.00081 19.3 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.1 KFX98413.1 - 0.00024 20.5 0.1 0.00082 18.8 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 KFX98413.1 - 0.0018 17.4 11.5 0.0059 15.7 8.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain adh_short PF00106.20 KFX98415.1 - 0.0051 16.7 0.1 0.0051 16.7 0.0 2.2 2 1 1 3 3 3 1 short chain dehydrogenase F-protein PF00469.15 KFX98415.1 - 0.015 14.7 0.0 0.017 14.4 0.0 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Med3 PF11593.3 KFX98415.1 - 0.027 13.6 4.0 0.026 13.7 2.8 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Val_tRNA-synt_C PF10458.4 KFX98415.1 - 0.044 13.8 1.6 0.081 13.0 1.1 1.4 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Auxin_repressed PF05564.7 KFX98415.1 - 0.2 12.2 2.3 0.26 11.8 1.6 1.2 1 0 0 1 1 1 0 Dormancy/auxin associated protein MSA-2c PF12238.3 KFX98415.1 - 3 7.4 6.1 3.8 7.1 4.2 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c LacAB_rpiB PF02502.13 KFX98416.1 - 2.5e-42 143.8 0.0 2.9e-42 143.6 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Glucokinase PF02685.11 KFX98416.1 - 0.099 11.3 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Glucokinase WD40 PF00400.27 KFX98417.1 - 0.011 15.5 0.3 0.017 15.0 0.2 1.2 1 0 0 1 1 1 0 WD domain, G-beta repeat Homeobox_KN PF05920.6 KFX98420.1 - 4.8e-13 48.5 0.2 1.4e-12 47.0 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KFX98420.1 - 2.9e-06 26.8 0.5 8.5e-06 25.2 0.3 1.8 1 0 0 1 1 1 1 Homeobox domain zf-C2H2_4 PF13894.1 KFX98420.1 - 0.00023 21.2 22.2 0.048 14.0 1.8 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFX98420.1 - 0.0047 17.2 21.6 0.88 10.0 0.1 4.7 3 1 1 4 4 4 3 Zinc finger, C2H2 type zf-met PF12874.2 KFX98420.1 - 0.062 13.5 10.1 11 6.4 0.7 4.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Laminin_G_1 PF00054.18 KFX98421.1 - 0.12 12.4 0.1 46 4.0 0.0 3.6 3 1 0 3 3 3 0 Laminin G domain SRP40_C PF05022.7 KFX98421.1 - 6.7 7.2 9.0 1.5e+02 2.9 0.0 5.4 5 1 1 6 6 6 0 SRP40, C-terminal domain GTP_EFTU PF00009.22 KFX98422.1 - 1.2e-45 155.2 0.0 2.1e-45 154.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 KFX98422.1 - 4.4e-26 90.5 0.1 1.6e-25 88.7 0.0 2.0 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.19 KFX98422.1 - 1e-17 63.7 0.1 2.7e-09 36.7 0.0 2.8 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KFX98422.1 - 3.3e-10 39.9 0.1 1.1e-09 38.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 KFX98422.1 - 0.042 13.3 0.0 0.32 10.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor G, domain IV MMR_HSR1 PF01926.18 KFX98422.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Vps5 PF09325.5 KFX98423.1 - 4.3e-12 45.7 0.7 7.1e-12 45.0 0.5 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KFX98423.1 - 8e-10 38.5 0.0 1.5e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 PX domain CCT_2 PF09425.5 KFX98423.1 - 0.18 11.3 3.7 6.2 6.4 0.0 2.7 2 0 0 2 2 2 0 Divergent CCT motif SAP PF02037.22 KFX98424.1 - 2.5e-13 49.1 0.2 5.3e-13 48.1 0.1 1.6 1 0 0 1 1 1 1 SAP domain Pribosyltran_N PF13793.1 KFX98425.1 - 2.1e-41 140.3 0.1 7e-39 132.1 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KFX98425.1 - 4.1e-33 114.6 0.0 3.4e-28 98.6 0.0 2.2 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KFX98425.1 - 3.4e-05 23.5 0.0 0.0012 18.5 0.0 2.7 3 0 0 3 3 3 1 Phosphoribosyl transferase domain XPG_I_2 PF12813.2 KFX98426.1 - 5.3e-62 209.5 0.0 8e-62 208.9 0.0 1.3 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 KFX98426.1 - 0.0018 18.3 0.0 0.0051 16.8 0.0 1.8 1 0 0 1 1 1 1 XPG I-region Pterin_bind PF00809.17 KFX98426.1 - 0.054 12.8 0.0 0.18 11.1 0.0 1.8 2 0 0 2 2 2 0 Pterin binding enzyme Fzo_mitofusin PF04799.8 KFX98426.1 - 0.13 11.6 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 fzo-like conserved region AATF-Che1 PF13339.1 KFX98426.1 - 0.32 11.1 3.5 0.22 11.7 0.6 2.1 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF383 PF04063.9 KFX98428.1 - 1.8e-69 233.1 0.0 7e-69 231.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 KFX98428.1 - 9.9e-22 76.2 2.7 1.2e-21 76.0 0.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF384) HEAT_2 PF13646.1 KFX98428.1 - 0.038 14.2 0.5 1.1 9.6 0.1 3.1 2 1 0 2 2 2 0 HEAT repeats Thi4 PF01946.12 KFX98431.1 - 6.6e-106 352.5 0.0 7.9e-106 352.3 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KFX98431.1 - 1.6e-06 27.2 0.5 2.9e-06 26.4 0.3 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KFX98431.1 - 3e-05 23.1 0.1 5.2e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KFX98431.1 - 4.8e-05 23.2 0.2 0.00013 21.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KFX98431.1 - 0.00047 19.9 0.1 0.0014 18.3 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KFX98431.1 - 0.00062 19.8 0.3 0.0016 18.5 0.1 1.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFX98431.1 - 0.0018 18.1 0.7 0.0035 17.2 0.4 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFX98431.1 - 0.0058 15.5 0.5 0.012 14.5 0.3 1.5 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KFX98431.1 - 0.026 13.6 0.3 0.04 12.9 0.2 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KFX98431.1 - 0.053 12.1 0.2 0.076 11.6 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.14 KFX98431.1 - 0.075 12.0 0.1 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KFX98431.1 - 0.12 10.7 0.7 0.18 10.2 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein Asparaginase PF00710.15 KFX98432.1 - 6.5e-98 327.4 0.0 8.6e-98 327.0 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 KFX98432.1 - 1.3e-12 47.9 1.3 2.8e-12 46.8 0.9 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFX98432.1 - 1.8e-09 37.8 0.4 6.1e-08 32.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFX98432.1 - 2.8e-09 36.9 0.3 1.2e-08 34.8 0.2 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 KFX98432.1 - 1.3e-08 34.1 1.0 1.3e-07 31.0 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 KFX98432.1 - 9.9e-06 25.3 0.0 0.00015 21.7 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat WD40 PF00400.27 KFX98433.1 - 4.1e-23 80.3 6.0 1.1e-06 28.3 0.0 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat Fungal_trans PF04082.13 KFX98434.1 - 2.7e-18 65.7 0.6 4.1e-18 65.1 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX98434.1 - 1e-06 28.5 8.6 2.3e-06 27.4 6.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 KFX98435.1 - 1.8e-06 27.5 0.1 7.7e-05 22.4 0.0 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat GatB_N PF02934.10 KFX98442.1 - 4.3e-100 334.3 0.0 5.6e-100 333.9 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 KFX98442.1 - 0.18 11.5 0.0 0.79 9.4 0.0 2.0 2 0 0 2 2 2 0 GatB domain DUF1788 PF08747.6 KFX98445.1 - 0.015 15.1 0.2 0.16 11.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1788) Rhv PF00073.15 KFX98445.1 - 0.079 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 picornavirus capsid protein GAT PF03127.9 KFX98445.1 - 0.096 12.6 6.7 1.4 8.9 0.4 3.4 3 2 0 3 3 3 0 GAT domain DUF948 PF06103.6 KFX98445.1 - 0.21 11.4 4.6 8.6 6.3 0.0 2.8 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Prefoldin_3 PF13758.1 KFX98445.1 - 1.2 8.9 5.2 1.2 8.9 0.6 2.6 3 1 0 3 3 3 0 Prefoldin subunit Snapin_Pallidin PF14712.1 KFX98445.1 - 2.1 8.7 7.2 5 7.5 0.5 3.0 2 1 1 3 3 3 0 Snapin/Pallidin PXA PF02194.10 KFX98468.1 - 8.4e-12 45.0 0.0 1.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 PXA domain FH2 PF02181.18 KFX98470.1 - 9e-79 265.0 7.6 1.1e-78 264.6 5.3 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain SET PF00856.23 KFX98479.1 - 1.2e-19 71.1 0.8 1.2e-19 71.1 0.6 3.5 3 2 0 3 3 3 1 SET domain His_Phos_2 PF00328.17 KFX98485.1 - 7.1e-76 255.7 0.1 1e-75 255.2 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Gly_transf_sug PF04488.10 KFX98494.1 - 1e-09 38.6 0.1 2.4e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif L_HGMIC_fpl PF10242.4 KFX98494.1 - 0.0026 17.8 0.0 0.0049 16.8 0.0 1.4 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein AA_permease_2 PF13520.1 KFX98495.1 - 9.3e-48 162.7 56.8 1.1e-47 162.5 39.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFX98495.1 - 6.6e-22 77.4 46.5 8.6e-22 77.1 32.3 1.0 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_2 PF00703.16 KFX98496.1 - 1.2e-10 41.7 2.2 4.8e-10 39.8 0.0 2.9 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KFX98496.1 - 9.3e-08 31.7 0.1 1.8e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Big_5 PF13205.1 KFX98496.1 - 0.074 13.6 0.4 0.074 13.6 0.3 3.2 2 1 0 2 2 2 0 Bacterial Ig-like domain Zn_clus PF00172.13 KFX98497.1 - 3.7e-06 26.7 10.3 3.7e-06 26.7 7.1 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.21 KFX98498.1 - 5.2e-11 42.2 0.0 8.6e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX98498.1 - 2e-10 40.3 0.0 6.5e-10 38.7 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.16 KFX98498.1 - 0.0088 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Flavin_Reduct PF01613.13 KFX98499.1 - 1.9e-12 47.3 0.0 3.2e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 KFX98499.1 - 8.2e-05 22.2 0.2 0.00059 19.4 0.2 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF447) Pyridox_oxidase PF01243.15 KFX98499.1 - 0.08 12.9 0.1 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Transferase PF02458.10 KFX98500.1 - 1.7e-39 135.5 0.0 8.8e-21 73.8 0.0 3.1 3 0 0 3 3 3 3 Transferase family Peptidase_S58 PF03576.9 KFX98501.1 - 8.3e-99 330.8 1.9 9.9e-99 330.6 1.3 1.0 1 0 0 1 1 1 1 Peptidase family S58 Glyco_hydro_7 PF00840.15 KFX98502.1 - 1.8e-151 504.4 4.7 2.2e-151 504.1 3.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 ADH_zinc_N PF00107.21 KFX98503.1 - 5.2e-24 84.2 0.4 9.3e-24 83.4 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX98503.1 - 1.9e-12 48.1 0.0 5.1e-12 46.7 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX98503.1 - 1.1e-07 31.5 0.0 3.1e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NSP10 PF09401.5 KFX98503.1 - 0.051 13.3 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA synthesis protein NSP10 U-box PF04564.10 KFX98505.1 - 1.7e-20 72.7 0.0 3e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 KFX98505.1 - 1.1e-18 66.6 4.7 1.1e-16 60.2 0.2 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFX98505.1 - 7.4e-07 28.5 4.7 0.0036 16.8 0.1 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFX98505.1 - 2.8e-05 23.6 5.9 0.0046 16.7 0.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFX98505.1 - 0.0001 22.8 3.8 0.00045 20.8 0.1 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFX98505.1 - 0.0043 17.1 0.3 0.026 14.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFX98505.1 - 0.037 13.8 0.9 0.12 12.1 0.2 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFX98505.1 - 0.047 13.6 4.8 3.6 7.6 0.7 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat zf-Nse PF11789.3 KFX98505.1 - 0.09 12.3 0.0 0.28 10.7 0.0 1.7 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit TPR_14 PF13428.1 KFX98505.1 - 0.1 13.2 0.5 0.1 13.2 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFX98505.1 - 1.5 9.2 5.2 2.1 8.7 0.4 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat UQ_con PF00179.21 KFX98507.1 - 2.9e-49 166.0 0.0 6.1e-49 165.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NAD_binding_6 PF08030.7 KFX98507.1 - 3.5e-32 111.4 0.0 1.1e-31 109.8 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFX98507.1 - 1.2e-19 70.1 0.0 3.1e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KFX98507.1 - 1.9e-18 66.7 17.4 8.9e-18 64.5 7.4 2.4 1 1 1 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KFX98507.1 - 0.00076 19.5 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Prok-E2_B PF14461.1 KFX98507.1 - 0.0014 18.3 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B 2-Hacid_dh PF00389.25 KFX98507.1 - 0.0081 15.6 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain RWD PF05773.17 KFX98507.1 - 0.052 13.4 0.1 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 RWD domain NAD_binding_1 PF00175.16 KFX98507.1 - 0.18 12.4 0.0 0.76 10.3 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Acyl-CoA_dh_N PF02771.11 KFX98508.1 - 1.7e-22 80.1 0.7 2.8e-22 79.4 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 KFX98508.1 - 2.4e-22 79.6 0.1 5.1e-22 78.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFX98508.1 - 2.8e-16 58.7 0.0 6.2e-16 57.6 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFX98508.1 - 2.8e-05 24.3 0.0 5.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain XPG_I PF00867.13 KFX98509.1 - 5.3e-31 106.5 0.5 2.4e-30 104.4 0.0 2.1 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 KFX98509.1 - 1e-20 73.8 0.1 2e-19 69.7 0.0 2.8 2 1 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.15 KFX98509.1 - 7.4e-06 26.1 0.1 6.6e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Linker_histone PF00538.14 KFX98510.1 - 1.3e-23 82.8 1.4 2.7e-23 81.8 1.0 1.5 1 0 0 1 1 1 1 linker histone H1 and H5 family Peptidase_S21 PF00716.12 KFX98510.1 - 0.48 9.7 15.6 0.23 10.7 9.4 1.4 1 1 0 1 1 1 0 Assemblin (Peptidase family S21) Menin PF05053.8 KFX98510.1 - 3.1 5.8 10.8 3.4 5.7 7.5 1.1 1 0 0 1 1 1 0 Menin PIP5K PF01504.13 KFX98511.1 - 3e-83 278.7 0.1 3e-83 278.7 0.1 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase IBR PF01485.16 KFX98512.1 - 6.8e-22 77.1 44.3 2.8e-11 43.0 3.5 4.4 3 1 1 4 4 4 3 IBR domain zf-C3HC4_2 PF13923.1 KFX98512.1 - 1.2e-05 25.2 7.8 1.2e-05 25.2 5.4 4.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX98512.1 - 0.00042 19.9 6.6 0.00042 19.9 4.6 4.6 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFX98512.1 - 0.0016 18.2 7.6 0.0016 18.2 5.3 3.7 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4_4 PF15227.1 KFX98512.1 - 0.013 15.3 28.6 0.062 13.1 0.6 4.7 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING XPG_I PF00867.13 KFX98513.1 - 2.4e-26 91.6 0.1 5.5e-26 90.4 0.1 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KFX98513.1 - 1.2e-20 73.6 0.0 2.6e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 KFX98513.1 - 0.00056 19.4 0.0 0.00098 18.6 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing DUF2962 PF11176.3 KFX98514.1 - 1.1e-43 148.4 1.0 1.3e-43 148.2 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) DUF3847 PF12958.2 KFX98514.1 - 0.058 13.1 2.7 0.1 12.3 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3847) PAS_9 PF13426.1 KFX98514.1 - 0.15 12.4 0.2 0.55 10.6 0.0 1.9 1 1 1 2 2 2 0 PAS domain MAM33 PF02330.11 KFX98515.1 - 9.8e-31 107.1 4.3 1.2e-30 106.8 3.0 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Cnd1_N PF12922.2 KFX98516.1 - 1.4e-58 197.3 0.3 1e-57 194.5 0.1 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 KFX98516.1 - 2.1e-54 184.0 6.1 2.1e-50 171.0 1.4 3.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KFX98516.1 - 1.8e-11 44.1 5.2 8.6e-06 25.9 0.0 5.7 5 2 1 6 6 6 2 HEAT repeats HEAT PF02985.17 KFX98516.1 - 2.4e-07 30.2 8.7 0.025 14.6 0.0 6.4 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 KFX98516.1 - 3.2e-05 24.2 9.0 0.024 15.1 0.0 5.6 5 1 1 6 6 6 2 HEAT-like repeat DUF2435 PF10363.4 KFX98516.1 - 0.01 15.6 0.0 5.2 7.0 0.0 3.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) Cohesin_HEAT PF12765.2 KFX98516.1 - 0.016 15.1 0.2 7.5 6.6 0.1 3.5 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion p450 PF00067.17 KFX98516.1 - 0.052 12.0 0.6 0.095 11.2 0.4 1.4 1 0 0 1 1 1 0 Cytochrome P450 Pkinase PF00069.20 KFX98517.1 - 6.7e-41 140.1 0.0 5.9e-37 127.2 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFX98517.1 - 5.9e-13 48.4 0.0 5.7e-07 28.8 0.0 3.7 3 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 KFX98517.1 - 3.8e-05 22.7 0.0 0.039 12.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KFX98517.1 - 0.0046 16.7 0.0 0.088 12.5 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Ribosomal_L18e PF00828.14 KFX98518.1 - 2.3e-34 118.5 0.1 3.2e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Helicase_C_2 PF13307.1 KFX98519.1 - 4.8e-55 186.0 0.0 1.3e-54 184.5 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 KFX98519.1 - 3.5e-48 163.2 0.0 5.7e-48 162.5 0.0 1.3 1 0 0 1 1 1 1 DEAD_2 PNP_UDP_1 PF01048.15 KFX98532.1 - 1.1e-05 24.5 0.0 1.2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily HsbA PF12296.3 KFX98533.1 - 1.4e-19 70.2 0.9 1.4e-19 70.2 0.6 1.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A DUF3566 PF12089.3 KFX98533.1 - 0.051 13.5 0.9 0.1 12.6 0.4 1.7 1 1 0 1 1 1 0 Transmembrane domain of unknown function (DUF3566) Sugar_tr PF00083.19 KFX98534.1 - 1.8e-90 303.6 18.9 2.1e-90 303.4 13.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX98534.1 - 2e-31 109.0 34.0 5.4e-27 94.4 17.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFX98534.1 - 0.00018 21.2 0.5 0.073 12.8 0.1 2.8 2 0 0 2 2 2 2 MFS_1 like family Folate_carrier PF01770.13 KFX98534.1 - 0.24 9.8 2.4 8.3 4.8 0.0 2.1 2 0 0 2 2 2 0 Reduced folate carrier Gly-zipper_OmpA PF13436.1 KFX98534.1 - 3.5 7.2 11.9 0.65 9.6 3.0 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain UPF0075 PF03702.9 KFX98535.1 - 5.1e-87 292.1 0.0 6e-87 291.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) Fibrillarin_2 PF10113.4 KFX98535.1 - 0.014 13.7 0.0 0.022 13.1 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein Peptidase_M22 PF00814.20 KFX98535.1 - 0.024 14.1 0.0 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 Glycoprotease family IRK_N PF08466.5 KFX98535.1 - 0.18 11.7 0.6 19 5.2 0.0 2.5 2 0 0 2 2 2 0 Inward rectifier potassium channel N-terminal Fungal_trans PF04082.13 KFX98536.1 - 4.5e-17 61.7 0.0 7.8e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX98536.1 - 0.00042 20.1 10.8 0.00076 19.3 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BT1 PF03092.11 KFX98536.1 - 0.073 11.7 0.0 0.22 10.2 0.0 1.7 2 0 0 2 2 2 0 BT1 family TraX PF05857.6 KFX98536.1 - 0.099 12.2 0.5 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 TraX protein Fungal_trans PF04082.13 KFX98537.1 - 1.6e-33 115.7 0.1 2.2e-33 115.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX98537.1 - 2.9e-08 33.4 11.8 4.8e-08 32.7 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 KFX98537.1 - 8.2e-05 22.4 0.1 0.00017 21.4 0.1 1.5 1 0 0 1 1 1 1 Gal4-like dimerisation domain Sugar_tr PF00083.19 KFX98538.1 - 2e-116 389.2 20.1 3.5e-116 388.4 14.0 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX98538.1 - 6.3e-25 87.6 62.3 4.1e-17 61.9 23.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA_17 PF13207.1 KFX98539.1 - 2.5e-06 28.3 0.0 1.6e-05 25.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 KFX98539.1 - 8.4e-06 25.4 0.0 1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 KFX98539.1 - 3.9e-05 23.7 0.0 6e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 KFX98539.1 - 0.0003 21.0 0.5 0.0014 18.9 0.4 2.3 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KFX98539.1 - 0.0007 18.5 0.0 0.036 12.9 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain AAA_28 PF13521.1 KFX98539.1 - 0.00071 19.5 0.0 0.0016 18.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFX98539.1 - 0.0011 18.0 0.2 0.0023 17.0 0.0 1.5 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 KFX98539.1 - 0.0014 18.4 0.2 0.067 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KFX98539.1 - 0.0043 16.6 0.1 0.0097 15.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 KFX98539.1 - 0.011 14.5 0.0 0.016 13.9 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_19 PF13245.1 KFX98539.1 - 0.013 15.1 1.3 0.067 12.9 0.1 2.5 2 1 1 3 3 3 0 Part of AAA domain AAA_26 PF13500.1 KFX98539.1 - 0.022 14.3 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain CoaE PF01121.15 KFX98539.1 - 0.032 13.6 0.4 6.5 6.1 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase T2SE PF00437.15 KFX98539.1 - 0.033 13.0 0.0 0.057 12.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein KTI12 PF08433.5 KFX98539.1 - 0.038 13.2 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 SRP54 PF00448.17 KFX98539.1 - 0.05 13.0 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain NACHT PF05729.7 KFX98539.1 - 0.052 13.1 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Mg_chelatase PF01078.16 KFX98539.1 - 0.056 12.6 0.0 0.42 9.7 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.18 KFX98539.1 - 0.077 12.9 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 KFX98539.1 - 0.081 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KFX98539.1 - 0.11 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA PF00004.24 KFX98539.1 - 0.12 12.5 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) 6PF2K PF01591.13 KFX98539.1 - 0.13 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Stc1 PF12898.2 KFX98544.1 - 6e-16 58.2 11.2 1.1e-15 57.4 7.8 1.5 1 0 0 1 1 1 1 Stc1 domain Cyclin_N PF00134.18 KFX98551.1 - 6.3e-11 41.9 0.1 1.3e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Mito_carr PF00153.22 KFX98552.1 - 1.2e-66 220.4 6.8 6.8e-23 80.1 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 KFX98552.1 - 1.3e-21 76.5 2.4 9.8e-10 38.4 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFX98552.1 - 9.1e-20 68.4 7.1 3.7e-06 25.8 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 KFX98552.1 - 4.8e-18 63.3 7.4 0.00023 20.7 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 KFX98552.1 - 2.5e-15 55.8 4.4 4.2e-07 29.4 0.1 3.4 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 KFX98552.1 - 2.5e-14 51.8 8.8 6e-06 25.3 0.1 3.6 3 0 0 3 3 3 3 EF hand SPARC_Ca_bdg PF10591.4 KFX98552.1 - 1.1e-05 25.4 0.2 0.11 12.5 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 KFX98552.1 - 0.011 15.6 0.4 2.3 8.2 0.0 3.5 3 1 1 4 4 4 0 EF-hand domain SET PF00856.23 KFX98598.1 - 4.4e-11 43.3 0.0 7.5e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.13 KFX98598.1 - 9e-06 25.4 8.4 9e-06 25.4 5.8 1.9 2 0 0 2 2 2 1 MYND finger Fer4_16 PF13484.1 KFX98598.1 - 0.018 15.7 0.8 0.018 15.7 0.5 3.1 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain AhpC-TSA PF00578.16 KFX98599.1 - 1.1e-32 112.2 0.0 1.6e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KFX98599.1 - 3.8e-13 49.2 0.0 5e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KFX98599.1 - 5.7e-11 41.8 0.1 1e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DNA_ligase_A_M PF01068.16 KFX98601.1 - 4.7e-45 153.4 0.0 8.5e-45 152.6 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KFX98601.1 - 5.7e-37 127.2 0.0 1.1e-36 126.2 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KFX98601.1 - 3.2e-15 56.2 0.0 1.2e-14 54.4 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 KFX98601.1 - 3e-07 30.5 0.2 3.7e-06 26.9 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.3 KFX98601.1 - 0.0089 15.7 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 DNA ligase IV UPRTase PF14681.1 KFX98602.1 - 8.4e-72 240.7 0.0 9.8e-72 240.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KFX98602.1 - 9.8e-06 25.3 0.1 2.6e-05 23.9 0.1 1.7 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.1 KFX98602.1 - 0.001 18.8 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain TMP-TENI PF02581.12 KFX98602.1 - 0.02 13.9 0.5 0.3 10.2 0.1 2.0 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI P5CR_dimer PF14748.1 KFX98602.1 - 0.045 13.7 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation Zn_clus PF00172.13 KFX98604.1 - 9e-07 28.7 11.9 1.3e-06 28.1 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sad1_UNC PF07738.8 KFX98605.1 - 7.5e-09 35.4 0.0 4.4e-07 29.7 0.0 2.5 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal Epimerase PF01370.16 KFX98606.1 - 2.2e-45 154.9 0.0 3.5e-45 154.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KFX98606.1 - 1.1e-23 82.9 0.1 2.1e-23 82.0 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 KFX98606.1 - 6.7e-17 61.0 0.0 1.1e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KFX98606.1 - 3.5e-14 52.3 0.0 2.6e-12 46.2 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KFX98606.1 - 1.2e-13 50.6 0.0 2.2e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KFX98606.1 - 4e-12 46.3 0.0 6.5e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX98606.1 - 7.8e-10 38.6 0.0 1.3e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 KFX98606.1 - 3.8e-09 35.8 0.0 1.2e-07 30.9 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 KFX98606.1 - 2.7e-07 30.7 0.0 4.9e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFX98606.1 - 0.00099 18.4 0.0 0.061 12.5 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family UDPG_MGDP_dh_N PF03721.9 KFX98606.1 - 0.0032 16.8 0.1 0.0058 16.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 KFX98606.1 - 0.1 11.4 0.1 0.2 10.5 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Biotin_lipoyl PF00364.17 KFX98613.1 - 7.1e-20 70.4 0.8 1.9e-19 69.0 0.5 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KFX98613.1 - 3.8e-05 23.2 0.5 0.00022 20.8 0.0 2.6 3 0 0 3 3 3 1 Biotin-lipoyl like E3_binding PF02817.12 KFX98613.1 - 0.0059 16.2 0.0 0.026 14.1 0.0 2.2 1 0 0 1 1 1 1 e3 binding domain HTH_Tnp_ISL3 PF13542.1 KFX98613.1 - 0.023 13.8 0.7 0.038 13.1 0.5 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Methyltransf_11 PF08241.7 KFX98614.1 - 1.2e-09 38.5 0.0 3.1e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX98614.1 - 5.7e-09 35.8 0.0 8.6e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX98614.1 - 7.5e-09 35.9 0.0 1.8e-08 34.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX98614.1 - 3e-06 26.5 0.0 5.9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KFX98614.1 - 5e-06 26.7 0.0 2.5e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX98614.1 - 9.3e-06 25.3 0.0 2.2e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX98614.1 - 0.00027 21.4 0.0 0.00075 20.0 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain DREV PF05219.7 KFX98614.1 - 0.16 10.7 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase AAA_2 PF07724.9 KFX98615.1 - 2.4e-47 161.0 0.0 3.6e-46 157.1 0.0 2.7 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KFX98615.1 - 2.7e-26 92.3 0.1 2.6e-14 53.5 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KFX98615.1 - 5.8e-25 86.9 0.2 2.1e-24 85.2 0.2 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_16 PF13191.1 KFX98615.1 - 4.5e-16 59.3 12.0 1e-05 25.5 0.0 6.5 3 2 2 6 6 6 2 AAA ATPase domain AAA_5 PF07728.9 KFX98615.1 - 6.3e-15 55.1 0.0 2.3e-09 37.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFX98615.1 - 5.7e-13 49.1 0.0 0.00012 22.2 0.0 3.7 2 2 1 3 3 3 2 AAA domain AAA_17 PF13207.1 KFX98615.1 - 2e-08 35.0 2.5 0.014 16.1 0.7 3.7 2 2 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 KFX98615.1 - 8.5e-08 31.8 0.0 4.5e-05 22.9 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.1 KFX98615.1 - 4.1e-07 30.3 0.4 0.013 15.7 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_19 PF13245.1 KFX98615.1 - 4.9e-07 29.4 0.0 0.03 14.0 0.0 3.1 2 0 0 2 2 2 2 Part of AAA domain IstB_IS21 PF01695.12 KFX98615.1 - 1e-06 28.3 0.0 0.029 13.7 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 KFX98615.1 - 4.2e-06 26.0 0.0 0.18 10.9 0.0 3.5 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI Clp_N PF02861.15 KFX98615.1 - 7.9e-06 25.7 3.0 0.0011 18.7 0.1 3.8 3 0 0 3 3 3 1 Clp amino terminal domain AAA_28 PF13521.1 KFX98615.1 - 3.8e-05 23.6 0.0 0.27 11.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KFX98615.1 - 4.7e-05 23.2 0.0 0.32 10.8 0.0 3.1 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KFX98615.1 - 6.2e-05 23.1 0.0 0.44 10.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase T2SE PF00437.15 KFX98615.1 - 9.6e-05 21.4 1.2 0.017 13.9 0.0 2.8 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_3 PF07726.6 KFX98615.1 - 0.00015 21.3 0.0 0.76 9.3 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KFX98615.1 - 0.00027 20.5 0.0 0.22 11.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KFX98615.1 - 0.0003 20.2 0.5 1.5 8.1 0.0 3.6 3 1 1 4 4 4 2 AAA domain Zeta_toxin PF06414.7 KFX98615.1 - 0.00039 19.5 0.0 0.045 12.8 0.0 3.0 3 0 0 3 3 3 1 Zeta toxin ResIII PF04851.10 KFX98615.1 - 0.0004 20.2 0.0 0.36 10.6 0.0 3.7 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit MobB PF03205.9 KFX98615.1 - 0.0007 19.3 0.0 1.6 8.3 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 KFX98615.1 - 0.0011 18.1 0.0 0.53 9.4 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFX98615.1 - 0.0015 17.9 0.0 1.1 8.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 KFX98615.1 - 0.0027 17.4 16.9 0.01 15.5 0.2 5.8 4 3 0 5 5 3 1 Archaeal ATPase ABC_tran PF00005.22 KFX98615.1 - 0.003 17.8 3.5 0.84 9.9 0.0 3.8 4 0 0 4 4 4 1 ABC transporter NACHT PF05729.7 KFX98615.1 - 0.0058 16.3 0.0 0.62 9.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Torsin PF06309.6 KFX98615.1 - 0.0098 15.7 0.0 0.082 12.7 0.0 2.4 3 0 0 3 3 3 1 Torsin AAA_10 PF12846.2 KFX98615.1 - 0.015 14.7 7.8 0.42 10.0 0.1 5.1 4 2 0 5 5 5 0 AAA-like domain AAA_21 PF13304.1 KFX98615.1 - 0.02 14.8 0.2 1.8 8.4 0.0 3.0 4 0 0 4 4 2 0 AAA domain NTPase_1 PF03266.10 KFX98615.1 - 0.021 14.5 0.0 0.4 10.3 0.0 2.6 2 0 0 2 2 2 0 NTPase SRP54 PF00448.17 KFX98615.1 - 0.036 13.4 0.0 7 6.0 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain UPF0079 PF02367.12 KFX98615.1 - 0.054 13.1 0.0 10 5.7 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 KFX98615.1 - 0.093 12.2 0.0 6.7 6.1 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation YycI PF09648.5 KFX98615.1 - 2 7.8 8.5 0.25 10.7 1.8 2.2 2 0 0 2 2 2 0 YycH protein Mhr1 PF12829.2 KFX98616.1 - 3.6e-28 97.2 0.1 6.7e-28 96.3 0.1 1.5 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination DUF1205 PF06722.7 KFX98616.1 - 0.0065 16.6 0.2 0.027 14.7 0.0 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF1205) DUF3431 PF11913.3 KFX98617.1 - 3.5e-85 285.0 1.0 4.8e-85 284.5 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Phasin PF05597.6 KFX98617.1 - 0.028 14.1 0.3 0.045 13.5 0.2 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) NACHT PF05729.7 KFX98618.1 - 8.7e-09 35.2 0.1 6.2e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KFX98618.1 - 7.1e-05 22.9 0.0 0.00028 21.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFX98618.1 - 0.00026 21.0 0.3 0.0017 18.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 KFX98618.1 - 0.071 13.3 0.0 0.35 11.0 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) BRE1 PF08647.6 KFX98619.1 - 3.7e-25 87.7 5.0 3.7e-25 87.7 3.5 6.4 5 1 2 7 7 5 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 KFX98619.1 - 5.7e-08 32.6 10.5 9.6e-08 31.9 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFX98619.1 - 1.9e-07 30.6 8.9 3.2e-07 29.9 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX98619.1 - 2.1e-07 30.4 11.7 3.7e-07 29.7 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX98619.1 - 5.8e-06 25.9 11.6 9.5e-06 25.2 8.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFX98619.1 - 8.6e-06 25.4 8.5 1.4e-05 24.7 5.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KFX98619.1 - 0.00039 20.0 6.9 0.00093 18.8 4.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Reo_sigmaC PF04582.7 KFX98619.1 - 0.0053 15.9 4.0 0.0053 15.9 2.8 4.9 2 2 2 5 5 5 2 Reovirus sigma C capsid protein zf-rbx1 PF12678.2 KFX98619.1 - 0.024 14.7 7.0 0.08 13.0 4.8 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 KFX98619.1 - 0.03 13.8 2.2 0.061 12.8 1.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF1272 PF06906.6 KFX98619.1 - 0.031 14.1 8.3 0.06 13.1 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C2H2 PF00096.21 KFX98619.1 - 0.034 14.4 1.3 2.3 8.7 0.1 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-RING_4 PF14570.1 KFX98619.1 - 0.042 13.4 7.3 0.13 11.8 5.2 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KFX98619.1 - 0.084 12.7 7.1 0.16 11.8 4.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KFX98619.1 - 0.12 12.1 1.8 0.26 11.0 1.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DinB_2 PF12867.2 KFX98619.1 - 0.18 12.1 5.7 0.27 11.5 1.7 2.9 2 1 0 2 2 2 0 DinB superfamily FYVE PF01363.16 KFX98619.1 - 1.3 8.9 11.5 19 5.2 8.0 2.4 1 1 1 2 2 2 0 FYVE zinc finger GAS PF13851.1 KFX98619.1 - 1.6 7.8 75.9 1.1 8.3 7.9 5.9 4 2 0 5 5 5 0 Growth-arrest specific micro-tubule binding zf-FCS PF06467.9 KFX98619.1 - 1.8 8.2 6.7 37 4.0 2.9 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_2 PF13465.1 KFX98619.1 - 1.8 8.9 6.0 8.2 6.9 1.6 2.4 2 0 0 2 2 2 0 Zinc-finger double domain SNF2_N PF00176.18 KFX98621.1 - 6.6e-71 238.5 0.4 6.6e-71 238.5 0.3 3.2 3 0 0 3 3 3 1 SNF2 family N-terminal domain HSA PF07529.8 KFX98621.1 - 6.7e-15 54.6 12.4 6.7e-15 54.6 8.6 3.1 3 0 0 3 3 3 1 HSA QLQ PF08880.6 KFX98621.1 - 3.2e-12 45.6 0.1 9.4e-12 44.1 0.1 1.9 1 0 0 1 1 1 1 QLQ Ubiq_cyt_C_chap PF03981.7 KFX98622.1 - 0.063 13.1 0.0 0.096 12.5 0.0 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone TPR_4 PF07721.9 KFX98622.1 - 0.55 10.8 2.4 0.62 10.6 0.3 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat SUR7 PF06687.7 KFX98622.1 - 1.8 8.0 7.2 2.7 7.4 5.0 1.3 1 0 0 1 1 1 0 SUR7/PalI family DUF2723 PF11028.3 KFX98622.1 - 4.4 6.7 7.2 1 8.8 0.7 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2723) Plasmodium_Vir PF05795.6 KFX98644.1 - 0.7 9.0 3.4 0.73 8.9 2.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Apt1 PF10351.4 KFX98644.1 - 4.3 6.0 7.6 5.2 5.8 5.3 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain MSP1_C PF07462.6 KFX98644.1 - 4.8 5.4 10.7 5.1 5.3 7.4 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Macoilin PF09726.4 KFX98644.1 - 7.6 4.6 12.7 8.3 4.5 8.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DNA_pol_viral_N PF00242.12 KFX98644.1 - 8.1 5.3 8.7 8.3 5.3 6.0 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain E_Pc_C PF06752.7 KFX98644.1 - 8.9 5.7 20.3 12 5.3 14.1 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus DUF3827 PF12877.2 KFX98644.1 - 8.9 4.2 14.4 12 3.8 9.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) CytochromB561_N PF09786.4 KFX98644.1 - 9.9 4.4 16.9 12 4.2 11.7 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal H_PPase PF03030.11 KFX98646.1 - 0.66 8.1 4.4 1.9 6.6 0.6 2.1 2 0 0 2 2 2 0 Inorganic H+ pyrophosphatase FAA_hydrolase PF01557.13 KFX98657.1 - 4.7e-65 219.0 0.0 6.2e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Glyoxalase PF00903.20 KFX98658.1 - 1.8e-06 27.9 3.7 3.8e-06 26.8 2.0 2.0 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 KFX98658.1 - 0.035 14.1 0.4 0.075 13.0 0.3 1.6 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KFX98658.1 - 0.13 12.9 0.5 4.8 7.8 0.1 2.4 2 0 0 2 2 2 0 Glyoxalase-like domain Fungal_trans PF04082.13 KFX98659.1 - 3e-16 59.0 3.2 6.4e-16 58.0 2.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX98659.1 - 5.6e-08 32.5 7.6 1.3e-07 31.3 5.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 KFX98660.1 - 1.2e-47 162.7 0.0 1.4e-47 162.5 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFX98660.1 - 1e-07 31.2 0.0 5.1e-05 22.3 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KFX98660.1 - 3.7e-06 26.1 0.0 0.0016 17.4 0.0 2.9 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KFX98660.1 - 6.3e-05 22.9 0.0 0.00047 20.1 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX98660.1 - 0.00013 21.9 0.0 0.0003 20.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFX98660.1 - 0.00077 18.4 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KFX98660.1 - 0.0008 17.9 0.0 0.0015 17.0 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 KFX98660.1 - 0.0045 16.1 0.0 0.0079 15.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 KFX98660.1 - 0.0057 15.5 0.0 0.0092 14.8 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KFX98660.1 - 0.0095 15.7 0.1 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KFX98660.1 - 0.016 14.2 0.1 0.022 13.8 0.1 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFX98660.1 - 0.032 14.6 0.1 0.21 12.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KFX98660.1 - 0.036 13.8 0.0 0.081 12.7 0.0 1.6 1 0 0 1 1 1 0 ThiF family ApbA PF02558.11 KFX98660.1 - 0.044 13.2 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 KFX98660.1 - 0.055 13.5 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KFX98660.1 - 0.087 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 KFX98660.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SnoaL_4 PF13577.1 KFX98661.1 - 4.1e-11 42.9 4.0 5.1e-11 42.5 2.8 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 KFX98661.1 - 0.0059 16.9 1.2 0.0093 16.3 0.8 1.3 1 0 0 1 1 1 1 SnoaL-like domain Rap1-DNA-bind PF09197.5 KFX98661.1 - 0.054 14.0 0.3 0.081 13.4 0.2 1.3 1 0 0 1 1 1 0 Rap1, DNA-binding DUF4440 PF14534.1 KFX98661.1 - 0.085 13.0 0.9 0.13 12.4 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Fungal_trans PF04082.13 KFX98662.1 - 1.5e-09 37.1 0.4 8.2e-09 34.7 0.0 2.3 1 1 1 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KFX98662.1 - 4.9e-08 32.8 14.0 0.00061 19.9 3.0 4.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX98662.1 - 5.9e-07 29.3 11.3 0.00044 20.3 2.5 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFX98662.1 - 0.00057 20.0 7.8 0.0051 17.0 2.1 3.0 2 0 0 2 2 2 1 Zinc-finger double domain zf-H2C2_5 PF13909.1 KFX98662.1 - 0.02 15.1 8.7 0.63 10.3 2.3 3.9 4 0 0 4 4 4 0 C2H2-type zinc-finger domain LIM PF00412.17 KFX98662.1 - 0.071 13.1 4.2 0.16 12.0 2.9 1.6 1 0 0 1 1 1 0 LIM domain HxlR PF01638.12 KFX98662.1 - 0.22 11.1 1.5 19 4.9 0.1 2.7 2 0 0 2 2 2 0 HxlR-like helix-turn-helix zf-C2H2_6 PF13912.1 KFX98662.1 - 5 7.1 13.9 2 8.4 0.4 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger COesterase PF00135.23 KFX98663.1 - 5.2e-55 187.1 0.0 7.8e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFX98663.1 - 2e-08 34.0 0.2 1.1e-07 31.6 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX98663.1 - 0.00071 19.3 0.1 0.0013 18.4 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX98663.1 - 0.0027 17.6 0.3 0.0039 17.0 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KFX98663.1 - 0.0051 15.5 0.7 0.025 13.2 0.5 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 KFX98663.1 - 0.0054 15.9 0.0 0.0087 15.2 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Leuk-A4-hydro_C PF09127.6 KFX98663.1 - 0.046 13.3 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal Esterase PF00756.15 KFX98663.1 - 0.13 11.7 0.1 0.38 10.1 0.1 1.8 1 1 0 1 1 1 0 Putative esterase CMD PF02627.15 KFX98664.1 - 1.7e-12 47.0 0.0 8.6e-10 38.3 0.0 2.2 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family TRI12 PF06609.8 KFX98665.1 - 2.5e-23 82.1 24.1 7.8e-23 80.5 16.7 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KFX98665.1 - 8.8e-21 73.9 43.3 1.4e-20 73.3 26.3 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TMEM220 PF15071.1 KFX98665.1 - 0.63 10.5 4.6 0.31 11.5 0.2 2.8 3 0 0 3 3 3 0 Transmembrane family 220, helix Fungal_trans PF04082.13 KFX98667.1 - 1.4e-06 27.3 0.1 2.5e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KFX98668.1 - 9e-32 110.1 52.2 2.2e-31 108.8 36.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily HTH_16 PF12645.2 KFX98668.1 - 0.083 12.8 0.1 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Glyco_hydro_3_C PF01915.17 KFX98669.1 - 1.1e-31 110.1 0.6 1.8e-30 106.1 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Beta-lactamase PF00144.19 KFX98669.1 - 0.00046 19.3 0.7 0.0011 18.0 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase Glyco_hydro_3 PF00933.16 KFX98670.1 - 2.3e-70 236.9 0.0 3e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFX98670.1 - 3.8e-06 26.5 0.0 5.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Sugar_tr PF00083.19 KFX98671.1 - 6e-114 381.0 30.2 8.5e-114 380.5 20.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX98671.1 - 8.9e-26 90.4 57.9 1.9e-19 69.6 13.0 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX98671.1 - 0.00015 20.3 31.8 0.042 12.2 0.9 4.0 4 0 0 4 4 4 4 MFS/sugar transport protein Glyco_hydro_3 PF00933.16 KFX98672.1 - 7.9e-71 238.4 0.0 1.1e-70 237.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFX98672.1 - 4.4e-39 134.3 0.1 1.9e-38 132.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFX98672.1 - 2.8e-20 72.0 0.0 5.5e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain GFO_IDH_MocA PF01408.17 KFX98673.1 - 1e-21 77.6 0.4 2.1e-21 76.6 0.3 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Fungal_trans PF04082.13 KFX98674.1 - 1.5e-23 82.9 0.0 2.2e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX98674.1 - 1.4 8.9 13.7 2.5 8.0 9.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GFO_IDH_MocA PF01408.17 KFX98675.1 - 4.7e-22 78.7 0.1 7.2e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KFX98675.1 - 1.5e-12 47.3 0.0 2.9e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 KFX98675.1 - 1.9e-05 24.9 0.0 3.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 KFX98675.1 - 7.9e-05 23.0 1.2 0.00011 22.6 0.2 1.7 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.15 KFX98675.1 - 0.00012 21.9 0.0 0.00056 19.8 0.0 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus LysR_substrate PF03466.15 KFX98675.1 - 0.0049 15.9 0.0 0.0082 15.2 0.0 1.3 1 0 0 1 1 1 1 LysR substrate binding domain F420_oxidored PF03807.12 KFX98675.1 - 0.0059 17.0 0.1 0.025 14.9 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent B12-binding PF02310.14 KFX98675.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 B12 binding domain Mac PF12464.3 KFX98676.1 - 1.1e-20 73.3 0.0 1.8e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 KFX98676.1 - 1.2e-14 53.0 6.8 1.5e-11 43.2 3.3 3.3 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KFX98676.1 - 2.2e-13 49.5 4.6 4.7e-11 42.0 2.8 2.8 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Sugar_tr PF00083.19 KFX98677.1 - 2.3e-83 280.2 16.9 2.7e-83 280.0 11.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX98677.1 - 2.6e-10 39.5 43.4 1.6e-08 33.6 21.8 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily Glucan_synthase PF02364.10 KFX98677.1 - 1.1 6.9 4.1 4.7 4.9 0.0 2.4 3 0 0 3 3 3 0 1,3-beta-glucan synthase component Glyco_tranf_2_3 PF13641.1 KFX98678.1 - 7.9e-08 32.3 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KFX98678.1 - 9.8e-07 28.2 0.0 1.7e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KFX98678.1 - 4.6e-05 23.1 0.0 0.0018 18.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 tRNA_int_endo PF01974.12 KFX98679.1 - 2e-21 75.5 0.2 4.2e-21 74.5 0.1 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 KFX98679.1 - 1.5e-05 24.4 0.0 0.0066 15.9 0.0 2.5 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain An_peroxidase PF03098.10 KFX98680.1 - 4.5e-96 322.3 0.0 9.6e-76 255.2 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.17 KFX98680.1 - 1.4e-11 43.6 0.0 8.7e-08 31.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 EXS PF03124.9 KFX98681.1 - 4.4e-96 321.9 24.7 5.5e-96 321.6 17.1 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 KFX98681.1 - 2.9e-57 194.5 0.3 4.5e-55 187.3 0.0 2.7 2 1 0 2 2 2 1 SPX domain Lipase_GDSL PF00657.17 KFX98682.1 - 2.3e-14 53.7 1.3 3e-14 53.4 0.9 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KFX98682.1 - 1.5e-13 51.2 3.9 2e-13 50.8 2.7 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family 2-Hacid_dh_C PF02826.14 KFX98683.1 - 4.2e-40 136.7 0.0 5.7e-40 136.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFX98683.1 - 4.9e-11 42.2 0.0 6.6e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFX98683.1 - 1.9e-09 37.5 0.1 9.3e-09 35.3 0.1 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KFX98683.1 - 0.00039 20.8 0.1 0.00073 19.9 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 KFX98683.1 - 0.0036 17.8 0.0 0.0086 16.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Radical_SAM PF04055.16 KFX98683.1 - 0.033 14.3 0.0 0.26 11.4 0.0 2.2 2 1 0 2 2 2 0 Radical SAM superfamily IlvN PF07991.7 KFX98683.1 - 0.035 13.4 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_10 PF13460.1 KFX98683.1 - 0.1 12.6 0.2 0.23 11.4 0.1 1.7 2 0 0 2 2 2 0 NADH(P)-binding NmrA PF05368.8 KFX98684.1 - 8.5e-20 70.9 0.1 1.1e-19 70.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX98684.1 - 2.2e-07 31.0 0.4 7e-07 29.4 0.1 1.8 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 KFX98684.1 - 0.00033 20.5 0.1 0.00073 19.4 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KFX98684.1 - 0.00074 19.0 0.0 0.014 14.8 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KFX98684.1 - 0.0088 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KFX98684.1 - 0.054 12.3 0.2 0.12 11.2 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein IPP-2 PF04979.9 KFX98685.1 - 1.3e-09 38.3 12.2 3.5e-07 30.5 1.3 2.3 1 1 1 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) CENP-C_C PF11699.3 KFX98686.1 - 0.00087 19.2 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_3 PF05899.7 KFX98686.1 - 0.0057 16.0 0.3 0.013 14.8 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF861) zf-C2H2 PF00096.21 KFX98686.1 - 0.0075 16.5 1.3 0.026 14.8 0.9 2.0 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX98686.1 - 0.014 15.7 0.4 0.037 14.3 0.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Cupin_2 PF07883.6 KFX98686.1 - 0.029 13.8 0.1 0.088 12.3 0.1 1.8 1 0 0 1 1 1 0 Cupin domain Peptidase_M18 PF02127.10 KFX98687.1 - 1.5e-126 422.4 0.0 2e-126 422.0 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) tRNA-synt_1e PF01406.14 KFX98687.1 - 9.2e-116 386.1 0.0 1.5e-115 385.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KFX98687.1 - 3.6e-06 25.8 0.1 0.076 11.6 0.0 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.6 KFX98687.1 - 0.00036 20.7 1.6 0.00041 20.5 0.0 2.0 2 0 0 2 2 2 1 DALR domain tRNA-synt_1c PF00749.16 KFX98687.1 - 0.13 10.9 4.7 0.23 10.0 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain HK97-gp10_like PF04883.7 KFX98687.1 - 0.41 11.5 3.9 0.44 11.5 0.7 2.6 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component GCD14 PF08704.5 KFX98688.1 - 1.5e-62 211.3 0.5 6.4e-43 147.0 0.0 2.7 1 1 1 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 KFX98688.1 - 0.0097 15.9 0.2 0.099 12.6 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain DUF3759 PF12585.3 KFX98689.1 - 4.7e-37 125.7 9.6 6.7e-37 125.2 6.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DNA_pol_lambd_f PF10391.4 KFX98693.1 - 6.2e-22 76.8 0.5 1.2e-21 76.0 0.3 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.1 KFX98693.1 - 2.1e-19 69.6 0.0 3.8e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 KFX98693.1 - 4.1e-18 64.8 0.0 6.7e-18 64.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 KFX98693.1 - 8.6e-08 32.2 0.0 1.8e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 KFX98693.1 - 0.076 13.3 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain Ecl1 PF12855.2 KFX98694.1 - 2e-11 42.9 2.7 3.8e-11 42.0 1.9 1.3 1 0 0 1 1 1 1 Life-span regulatory factor DUF329 PF03884.9 KFX98694.1 - 0.057 12.9 2.1 0.12 11.9 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF329) zf-FCS PF06467.9 KFX98694.1 - 0.064 12.8 0.8 0.12 11.9 0.6 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DUF581 PF04570.9 KFX98694.1 - 0.071 12.4 4.7 0.4 9.9 3.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF581) Cornifin PF02389.10 KFX98699.1 - 0.68 9.6 10.5 1 9.0 7.3 1.3 1 0 0 1 1 1 0 Cornifin (SPRR) family RRM_1 PF00076.17 KFX98715.1 - 1.4e-12 47.0 0.0 2.2e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX98715.1 - 8.4e-09 35.2 0.0 1.7e-08 34.3 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX98715.1 - 1.2e-06 28.2 0.0 1.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSD PF00313.17 KFX98715.1 - 0.0026 17.5 0.1 0.0059 16.3 0.1 1.7 2 1 0 2 2 2 1 'Cold-shock' DNA-binding domain Ndc80_HEC PF03801.8 KFX98716.1 - 2.2e-44 150.6 0.5 4.1e-44 149.8 0.4 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family Tropomyosin PF00261.15 KFX98716.1 - 3.5e-07 29.5 15.2 3.5e-07 29.5 10.5 3.5 2 2 1 3 3 3 1 Tropomyosin WASH_WAHD PF11945.3 KFX98716.1 - 0.00034 19.9 2.6 0.00034 19.9 1.8 1.9 3 0 0 3 3 3 1 WAHD domain of WASH complex Filament PF00038.16 KFX98716.1 - 0.00037 20.0 42.2 0.0078 15.7 9.6 3.2 2 1 1 3 3 3 3 Intermediate filament protein FliJ PF02050.11 KFX98716.1 - 0.0091 16.0 4.1 0.0091 16.0 2.9 3.7 3 1 0 4 4 4 2 Flagellar FliJ protein Reo_sigmaC PF04582.7 KFX98716.1 - 0.28 10.3 4.2 0.87 8.6 0.3 2.4 2 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF2379 PF09543.5 KFX98716.1 - 0.46 10.4 10.7 0.17 11.8 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2379) NPV_P10 PF05531.7 KFX98716.1 - 1 9.6 11.2 0.89 9.8 0.7 4.2 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein FtsL PF04999.8 KFX98716.1 - 1.5 8.5 9.5 3 7.6 0.1 3.3 3 0 0 3 3 3 0 Cell division protein FtsL FliD_C PF07195.7 KFX98716.1 - 4.9 6.3 19.7 1.3 8.3 0.7 3.8 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 C-terminus Tropomyosin_1 PF12718.2 KFX98716.1 - 7.9 6.3 52.0 2.9 7.7 13.3 4.4 2 2 2 4 4 4 0 Tropomyosin like ATG16 PF08614.6 KFX98716.1 - 9.2 6.0 33.6 3.9 7.2 5.1 3.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) PI-PLC-X PF00388.14 KFX98723.1 - 1.3e-49 167.3 0.1 2.1e-49 166.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KFX98723.1 - 7.1e-34 116.3 0.0 1.3e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 KFX98723.1 - 0.043 13.8 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like CAF1 PF04857.15 KFX98740.1 - 8.3e-54 182.6 0.0 1.1e-53 182.2 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease RFX_DNA_binding PF02257.10 KFX98740.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 RFX DNA-binding domain DUF155 PF02582.9 KFX98741.1 - 8.1e-56 188.6 0.3 1.1e-55 188.2 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.1 KFX98741.1 - 0.033 14.3 0.0 0.076 13.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Sugar_tr PF00083.19 KFX98742.1 - 1.8e-66 224.6 24.1 2e-66 224.4 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX98742.1 - 1.8e-06 26.9 39.8 4.8e-06 25.5 25.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fmp27 PF10344.4 KFX98743.1 - 2.3e-213 710.5 0.0 4e-213 709.7 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 KFX98743.1 - 1.5e-169 564.7 5.1 1.5e-169 564.7 3.5 2.5 3 0 0 3 3 3 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 KFX98743.1 - 6.7e-146 486.4 0.0 1.4e-145 485.3 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 KFX98743.1 - 2.7e-54 183.2 0.2 6e-54 182.0 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.4 KFX98743.1 - 1.9e-52 177.2 0.0 4.3e-52 176.1 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.4 KFX98743.1 - 2e-32 111.6 0.0 7.9e-32 109.7 0.0 2.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain RRM_6 PF14259.1 KFX98744.1 - 1.2e-10 41.1 0.0 2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFX98744.1 - 1.4e-08 34.2 0.0 2.3e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX98744.1 - 0.00013 21.7 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tombus_movement PF05318.7 KFX98744.1 - 0.34 11.5 6.2 1.9 9.2 4.3 2.3 1 0 0 1 1 1 0 Tombusvirus movement protein PTS_2-RNA PF01885.11 KFX98775.1 - 6e-23 81.1 0.1 7.1e-23 80.8 0.1 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.12 KFX98775.1 - 0.059 13.1 0.0 0.082 12.7 0.0 1.3 1 0 0 1 1 1 0 La domain Aldo_ket_red PF00248.16 KFX98776.1 - 1.1e-51 175.3 0.0 1.4e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Med1 PF10744.4 KFX98779.1 - 3.3e-42 144.6 0.0 5.5e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Glyco_tranf_2_4 PF13704.1 KFX98783.1 - 2.2e-07 31.0 0.4 4.8e-07 30.0 0.1 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.22 KFX98783.1 - 0.0003 20.1 0.3 0.00065 19.1 0.2 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 92 DUF1541 PF07563.6 KFX98784.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) Crystall_3 PF08964.5 KFX98785.1 - 0.063 13.0 0.0 0.11 12.2 0.0 1.6 1 1 0 1 1 1 0 Beta/Gamma crystallin LysM PF01476.15 KFX98786.1 - 2.5e-05 24.0 0.0 0.37 10.7 0.0 3.3 3 0 0 3 3 3 3 LysM domain ETF_QO PF05187.8 KFX98788.1 - 1.2e-41 141.1 0.0 1.9e-41 140.4 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase Fer4_7 PF12838.2 KFX98788.1 - 0.0034 17.7 1.2 0.0083 16.4 0.8 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain DAO PF01266.19 KFX98788.1 - 0.015 14.2 0.2 0.1 11.5 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Fer4_10 PF13237.1 KFX98788.1 - 0.09 12.5 0.7 0.23 11.3 0.5 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain FAA_hydrolase_N PF09298.6 KFX98789.1 - 0.089 12.7 0.6 0.16 11.9 0.4 1.4 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal RR_TM4-6 PF06459.7 KFX98789.1 - 0.37 10.6 5.7 0.52 10.1 3.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 KAR9 PF08580.5 KFX98789.1 - 0.51 8.5 8.3 0.6 8.3 5.7 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF676 PF05057.9 KFX98790.1 - 1.6e-49 168.1 0.0 2.4e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KFX98790.1 - 1.4e-05 24.7 0.0 2.2e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KFX98790.1 - 0.00043 20.0 0.0 0.00063 19.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFX98790.1 - 0.0024 17.8 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KFX98790.1 - 0.037 13.6 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) LCAT PF02450.10 KFX98790.1 - 0.12 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase HDV_ag PF01517.13 KFX98790.1 - 0.14 11.7 0.1 2.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Hepatitis delta virus delta antigen CMAS PF02353.15 KFX98792.1 - 2.3e-59 200.7 0.0 2.9e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KFX98792.1 - 1.3e-13 51.0 0.0 2.4e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX98792.1 - 3.6e-09 36.9 0.0 8.1e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX98792.1 - 2.1e-05 24.1 0.0 3.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX98792.1 - 0.00044 20.5 0.0 0.001 19.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX98792.1 - 0.0013 19.1 0.0 0.004 17.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFX98792.1 - 0.0019 17.5 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KFX98792.1 - 0.0036 17.8 0.1 0.01 16.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX98792.1 - 0.0054 16.7 0.0 0.019 14.9 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.8 KFX98792.1 - 0.0096 15.2 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.14 KFX98792.1 - 0.013 15.0 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) EF-hand_4 PF12763.2 KFX98793.1 - 2.9e-25 88.0 0.0 4.5e-12 45.6 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.6 KFX98793.1 - 2.6e-07 30.6 30.9 2.6e-07 30.6 21.4 7.4 5 1 2 7 7 7 3 Domain of unknown function (DUF1720) WH2 PF02205.15 KFX98793.1 - 1.9e-06 27.3 0.5 4.9e-06 25.9 0.3 1.7 1 0 0 1 1 1 1 WH2 motif EF-hand_7 PF13499.1 KFX98793.1 - 0.0035 17.4 0.0 0.64 10.1 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KFX98793.1 - 0.014 14.6 0.0 4.9 6.6 0.0 2.5 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 KFX98793.1 - 0.11 12.4 0.1 5.6 7.1 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain RAMP4 PF06624.7 KFX98795.1 - 1.2e-07 31.1 0.1 1.5e-07 30.8 0.1 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 UPF0233 PF06781.7 KFX98795.1 - 0.14 11.7 0.2 0.2 11.2 0.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0233) MRAP PF15183.1 KFX98795.1 - 0.68 9.5 3.3 0.93 9.1 0.3 2.0 1 1 1 2 2 2 0 Melanocortin-2 receptor accessory protein family Adaptin_N PF01602.15 KFX98796.1 - 2.2e-78 263.8 0.0 3.2e-78 263.3 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region SMAP PF15477.1 KFX98796.1 - 5e-16 58.7 2.6 5e-16 58.7 1.8 4.4 3 1 0 3 3 3 1 Small acidic protein family TPR_11 PF13414.1 KFX98797.1 - 5.2e-09 35.6 2.1 6.9e-05 22.4 0.1 4.0 3 1 2 5 5 5 2 TPR repeat TPR_16 PF13432.1 KFX98797.1 - 7.7e-08 32.8 2.3 0.00032 21.2 0.2 4.3 2 1 3 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFX98797.1 - 2.7e-07 30.6 6.1 0.0057 17.1 0.2 5.2 3 1 3 6 6 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFX98797.1 - 1.1e-06 28.8 0.7 0.0017 18.6 0.2 3.5 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFX98797.1 - 1.8e-06 27.4 0.8 0.0027 17.5 0.1 4.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFX98797.1 - 4.4e-06 26.5 4.7 0.2 11.5 0.4 4.5 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFX98797.1 - 1.2e-05 25.0 0.1 0.03 14.5 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFX98797.1 - 0.0002 20.8 0.0 0.0027 17.3 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFX98797.1 - 0.0032 17.3 0.3 0.017 14.9 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFX98797.1 - 0.011 16.1 1.4 11 6.6 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFX98797.1 - 0.026 14.1 0.0 4 7.2 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Clathrin PF00637.15 KFX98797.1 - 0.047 13.2 0.3 3.1 7.3 0.0 2.7 1 1 1 2 2 2 0 Region in Clathrin and VPS FmrO PF07091.6 KFX98797.1 - 0.049 12.6 0.0 0.088 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) TPR_20 PF14561.1 KFX98797.1 - 0.066 13.3 0.4 0.65 10.1 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat Ada_Zn_binding PF02805.11 KFX98801.1 - 3.5e-30 103.3 3.2 5.6e-30 102.7 2.2 1.3 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 KFX98801.1 - 3.3e-07 29.9 0.0 8.2e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 KFX98801.1 - 0.0011 19.0 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain DNA_binding_1 PF01035.15 KFX98802.1 - 2.8e-23 81.4 0.0 3.4e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Utp8 PF10395.4 KFX98804.1 - 2e-05 23.1 3.5 0.012 13.9 1.3 2.5 2 1 0 2 2 2 2 Utp8 family AAA PF00004.24 KFX98805.1 - 1.9e-09 37.7 1.1 5.2e-08 33.1 0.8 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KFX98805.1 - 4.5e-05 22.3 1.2 0.001 17.8 0.0 2.7 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 KFX98805.1 - 0.00019 22.2 0.0 0.00056 20.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFX98805.1 - 0.00038 20.5 0.1 0.0035 17.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFX98805.1 - 0.0022 17.9 0.1 0.0083 16.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.10 KFX98805.1 - 0.0025 17.5 0.0 0.5 10.0 0.0 2.3 2 0 0 2 2 2 1 NTPase AAA_14 PF13173.1 KFX98805.1 - 0.015 15.1 0.0 0.069 13.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFX98805.1 - 0.038 13.9 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFX98805.1 - 0.063 13.1 0.0 0.24 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 KFX98805.1 - 0.076 11.7 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 KFX98805.1 - 0.087 13.0 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 KFX98805.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase RuvB_N PF05496.7 KFX98805.1 - 0.14 11.2 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus SGL PF08450.7 KFX98811.1 - 2.2e-62 210.6 0.0 2.6e-62 210.3 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region ParcG PF10274.4 KFX98811.1 - 0.0037 17.1 0.0 0.0059 16.5 0.0 1.2 1 0 0 1 1 1 1 Parkin co-regulated protein Arylesterase PF01731.15 KFX98811.1 - 0.012 15.5 0.0 0.031 14.2 0.0 1.7 1 0 0 1 1 1 0 Arylesterase Reg_prop PF07494.6 KFX98811.1 - 0.12 12.5 4.8 3.6 7.9 0.0 4.0 3 0 0 3 3 3 0 Two component regulator propeller adh_short PF00106.20 KFX98812.1 - 4.1e-29 101.6 0.2 5.2e-29 101.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX98812.1 - 4.4e-24 85.5 0.1 5.7e-24 85.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX98812.1 - 1.9e-12 47.2 0.1 2.7e-12 46.7 0.1 1.2 1 0 0 1 1 1 1 KR domain MtrA PF04208.9 KFX98812.1 - 0.016 14.6 0.1 0.029 13.8 0.1 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A Fungal_trans PF04082.13 KFX98813.1 - 3.1e-30 104.9 0.3 5.3e-30 104.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DHDPS PF00701.17 KFX98813.1 - 1.8e-08 33.3 0.0 2.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Zn_clus PF00172.13 KFX98813.1 - 5.9e-07 29.2 10.4 1.2e-06 28.2 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHDPS PF00701.17 KFX98814.1 - 1.5e-06 27.0 0.0 1.6e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MR_MLE_C PF13378.1 KFX98815.1 - 1.1e-30 105.8 0.0 2e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like Aldose_epim PF01263.15 KFX98815.1 - 6.1e-23 81.3 0.0 9.6e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase MR_MLE_N PF02746.11 KFX98815.1 - 3.1e-16 59.4 0.0 7e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 KFX98815.1 - 1.3e-08 35.2 0.0 4.4e-08 33.5 0.0 2.0 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Sugar_tr PF00083.19 KFX98816.1 - 3e-86 289.7 22.8 3.5e-86 289.5 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX98816.1 - 5.1e-41 140.5 37.8 5e-35 120.8 16.3 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX98816.1 - 1.5e-08 33.4 16.6 4.4e-07 28.6 3.1 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein DUF389 PF04087.9 KFX98816.1 - 0.018 14.9 0.7 0.084 12.8 0.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF389) Lipase_GDSL_2 PF13472.1 KFX98817.1 - 7.8e-12 45.6 0.5 1.1e-11 45.2 0.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFX98817.1 - 1.5e-05 24.9 0.1 2.2e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_2_C PF02836.12 KFX98818.1 - 1.5e-98 329.4 0.0 2.1e-98 328.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 KFX98818.1 - 4.5e-56 189.8 0.0 6.3e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 KFX98818.1 - 1.3e-50 171.2 0.7 2e-50 170.5 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KFX98818.1 - 4.3e-10 40.0 0.7 1.2e-09 38.6 0.0 2.2 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_42 PF02449.10 KFX98818.1 - 0.015 14.4 0.1 0.028 13.5 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase PhyH PF05721.8 KFX98819.1 - 1.9e-11 44.4 0.0 3.6e-11 43.5 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_43 PF04616.9 KFX98820.1 - 2e-09 36.9 9.2 7.7e-09 35.0 2.3 1.9 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Aldo_ket_red PF00248.16 KFX98821.1 - 5.1e-65 219.0 0.0 6.1e-65 218.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_2_N PF02837.13 KFX98822.1 - 6.4e-34 116.9 0.2 3.1e-33 114.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KFX98822.1 - 2.9e-28 98.6 0.0 5.9e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KFX98822.1 - 3.2e-14 53.3 0.1 8.5e-14 51.9 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 KFX98822.1 - 0.00031 21.0 0.4 0.0034 17.6 0.0 2.8 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain CBM-like PF14683.1 KFX98823.1 - 5.6e-31 107.4 0.9 9.4e-31 106.6 0.1 1.8 2 1 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 KFX98823.1 - 1.3e-21 76.5 4.2 1.6e-20 73.0 0.4 3.3 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 KFX98823.1 - 2.7e-07 30.5 0.6 9.1e-07 28.8 0.4 1.9 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 KFX98823.1 - 0.0014 18.6 0.7 0.0029 17.6 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4480) Dirigent PF03018.9 KFX98823.1 - 0.0021 17.5 0.0 0.0052 16.2 0.0 1.6 1 0 0 1 1 1 1 Dirigent-like protein DUF4198 PF10670.4 KFX98823.1 - 0.005 16.8 0.0 0.029 14.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4198) phage_tail_N PF08400.5 KFX98823.1 - 0.047 13.4 0.2 0.086 12.5 0.1 1.4 1 0 0 1 1 1 0 Prophage tail fibre N-terminal Pex24p PF06398.6 KFX98825.1 - 2.6e-52 177.8 0.2 3.2e-52 177.5 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.3 KFX98825.1 - 0.013 13.3 0.7 0.042 11.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) Pkinase PF00069.20 KFX98826.1 - 6.4e-56 189.3 0.0 1.1e-55 188.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX98826.1 - 2.2e-18 66.2 0.1 7.1e-18 64.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KFX98826.1 - 0.13 12.0 0.0 0.32 10.6 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFX98826.1 - 0.13 11.8 0.2 0.3 10.6 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase NAD_binding_1 PF00175.16 KFX98826.1 - 0.15 12.6 0.1 0.28 11.7 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain NAM-associated PF14303.1 KFX98826.1 - 7.1 6.9 9.7 0.83 9.9 2.9 2.3 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain APC_CDC26 PF10471.4 KFX98832.1 - 8.2e-12 45.7 2.8 9.8e-12 45.4 1.9 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 LcrG PF07216.7 KFX98832.1 - 0.088 12.8 0.4 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 LcrG protein Peptidase_M1 PF01433.15 KFX98833.1 - 8e-05 21.9 0.0 0.0084 15.2 0.0 2.9 3 0 0 3 3 3 2 Peptidase family M1 SAS4 PF15460.1 KFX98834.1 - 1.4e-34 117.9 0.2 3.2e-34 116.8 0.1 1.6 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Adaptin_binding PF10199.4 KFX98834.1 - 0.0037 17.5 1.6 0.0037 17.5 1.1 2.3 2 1 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 MYCBPAP PF14646.1 KFX98834.1 - 0.063 11.9 2.6 0.074 11.7 0.7 1.7 2 0 0 2 2 2 0 MYCBP-associated protein family CENP-F_leu_zip PF10473.4 KFX98838.1 - 0.04 13.7 2.1 0.05 13.4 1.5 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Clusterin PF01093.12 KFX98838.1 - 0.048 12.4 0.3 0.057 12.2 0.2 1.0 1 0 0 1 1 1 0 Clusterin FlxA PF14282.1 KFX98838.1 - 0.078 12.9 2.6 0.093 12.6 1.8 1.2 1 0 0 1 1 1 0 FlxA-like protein APG6 PF04111.7 KFX98838.1 - 0.11 11.5 1.7 0.11 11.4 1.2 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 CALCOCO1 PF07888.6 KFX98838.1 - 0.3 9.3 3.6 0.35 9.0 2.5 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like IncA PF04156.9 KFX98838.1 - 1.1 8.7 4.2 1.5 8.4 2.9 1.2 1 0 0 1 1 1 0 IncA protein ABC2_membrane PF01061.19 KFX98847.1 - 2.3e-91 304.6 57.0 8.9e-50 168.7 16.2 2.7 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 KFX98847.1 - 3.3e-37 126.2 0.1 3.9e-29 100.3 0.0 3.0 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 KFX98847.1 - 4.5e-36 124.1 0.0 2.1e-17 63.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 KFX98847.1 - 8.6e-36 121.8 0.2 5.5e-22 77.6 0.0 2.7 1 1 1 2 2 2 2 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KFX98847.1 - 4.2e-07 29.5 0.2 7.5e-05 22.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 KFX98847.1 - 1.4e-05 24.2 0.1 0.0016 17.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 KFX98847.1 - 4.4e-05 22.6 9.5 4.4e-05 22.6 6.6 3.7 2 2 0 2 2 2 1 ABC-2 family transporter protein AAA_16 PF13191.1 KFX98847.1 - 0.00012 22.0 5.1 0.00063 19.7 0.1 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 KFX98847.1 - 0.00013 21.8 0.1 0.014 15.2 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KFX98847.1 - 0.00022 20.6 0.8 0.033 13.7 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.1 KFX98847.1 - 0.0013 18.7 0.2 1.7 8.5 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KFX98847.1 - 0.0054 16.8 0.1 1.5 8.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KFX98847.1 - 0.0084 15.3 0.0 0.47 9.6 0.0 2.9 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.14 KFX98847.1 - 0.012 15.1 2.0 0.14 11.5 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 KFX98847.1 - 0.012 15.3 1.3 1.9 8.2 0.1 2.8 2 0 0 2 2 2 0 Part of AAA domain Peptidase_M50 PF02163.17 KFX98847.1 - 0.013 14.4 0.1 3.3 6.6 1.8 3.2 2 1 0 2 2 2 0 Peptidase family M50 AAA_17 PF13207.1 KFX98847.1 - 0.017 15.9 0.0 0.91 10.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KFX98847.1 - 0.019 15.2 0.1 0.59 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KFX98847.1 - 0.073 12.7 1.9 2.2 7.9 0.3 2.5 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.18 KFX98847.1 - 0.15 12.0 0.0 12 5.9 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 KFX98847.1 - 0.31 10.7 0.0 14 5.3 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase CTP_transf_2 PF01467.21 KFX98849.1 - 2e-26 92.9 0.0 2.6e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase Sugar_tr PF00083.19 KFX98850.1 - 3.6e-33 114.8 34.8 5.8e-20 71.2 11.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFX98850.1 - 1.3e-19 70.1 41.5 6.7e-10 38.1 17.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 KFX98850.1 - 0.019 13.4 20.5 0.24 9.8 2.2 2.5 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like Cation_efflux PF01545.16 KFX98850.1 - 0.5 9.3 7.2 0.74 8.8 0.1 2.8 2 1 1 3 3 3 0 Cation efflux family DUF1228 PF06779.9 KFX98850.1 - 5.9 6.9 11.2 0.15 12.1 1.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) CK1gamma_C PF12605.3 KFX98851.1 - 0.69 10.5 9.5 0.92 10.1 6.6 1.2 1 0 0 1 1 1 0 Casein kinase 1 gamma C terminal WD40 PF00400.27 KFX98879.1 - 3.8e-18 64.5 0.8 5.8e-05 22.8 0.0 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat SRA1 PF07304.6 KFX98879.1 - 1.8e-09 37.5 0.0 1.8e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 KFX98879.1 - 0.00015 21.6 0.0 0.0005 19.9 0.0 1.8 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Apc4_WD40 PF12894.2 KFX98879.1 - 0.0072 15.8 0.0 0.081 12.4 0.0 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Dak1_2 PF13684.1 KFX98879.1 - 0.24 10.2 0.2 0.45 9.3 0.2 1.3 1 0 0 1 1 1 0 Dihydroxyacetone kinase family RRM_1 PF00076.17 KFX98880.1 - 4.5e-16 58.2 0.0 6.8e-16 57.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX98880.1 - 5.4e-12 45.5 0.0 7.8e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFX98880.1 - 4.9e-08 32.7 0.0 7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2167 PF09935.4 KFX98880.1 - 0.062 12.1 0.0 0.075 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2167) B12D PF06522.6 KFX98881.1 - 3.4e-05 23.4 0.0 5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Velvet PF11754.3 KFX98885.1 - 1.3e-40 139.1 0.0 1.5e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Velvet factor Fer2_3 PF13085.1 KFX98886.1 - 5e-30 103.5 0.0 8.3e-30 102.8 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 KFX98886.1 - 6.3e-10 39.2 6.5 6.3e-10 39.2 4.5 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 KFX98886.1 - 6.2e-09 35.7 4.8 6.2e-09 35.7 3.4 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 KFX98886.1 - 0.00017 21.9 10.2 0.00024 21.4 1.1 2.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 KFX98886.1 - 0.00017 21.7 3.7 0.043 14.0 0.3 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 KFX98886.1 - 0.00058 19.6 5.0 0.00058 19.6 3.4 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 KFX98886.1 - 0.0073 16.0 0.4 0.0073 16.0 0.3 2.4 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 KFX98886.1 - 0.0099 16.2 6.6 0.0099 16.2 4.6 2.4 2 1 1 3 3 3 2 4Fe-4S dicluster domain DNA_pol3_tau_4 PF12168.3 KFX98886.1 - 0.88 10.0 3.6 2.1 8.7 0.9 2.2 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_15 PF13459.1 KFX98886.1 - 3.8 8.1 7.8 1 9.9 0.1 2.8 3 0 0 3 3 3 0 4Fe-4S single cluster domain Evr1_Alr PF04777.8 KFX98887.1 - 8.4e-29 99.3 0.1 1.2e-28 98.8 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Med27 PF11571.3 KFX98887.1 - 0.069 13.2 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 27 R3H PF01424.17 KFX98888.1 - 1.5e-13 50.2 0.0 2.7e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 KFX98888.1 - 0.003 17.4 14.3 0.003 17.4 9.9 8.6 10 0 0 10 10 10 5 NF-X1 type zinc finger TPR_11 PF13414.1 KFX98889.1 - 5.2e-09 35.6 2.0 1.3e-07 31.1 0.2 2.7 2 1 1 3 3 3 2 TPR repeat Zn_clus PF00172.13 KFX98889.1 - 1.8e-06 27.7 10.2 3.3e-06 26.8 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_16 PF13432.1 KFX98889.1 - 0.00092 19.8 4.5 0.84 10.3 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.1 KFX98889.1 - 0.0011 18.7 1.1 0.31 10.9 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFX98889.1 - 0.0042 17.6 2.2 0.082 13.5 0.3 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Fungal_trans_2 PF11951.3 KFX98889.1 - 0.016 13.8 0.1 0.027 13.0 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain TPR_2 PF07719.12 KFX98889.1 - 0.02 14.7 4.2 0.76 9.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFX98889.1 - 0.058 13.0 2.6 1.6 8.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFX98889.1 - 0.31 11.4 2.9 4.9 7.5 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Lipase_GDSL PF00657.17 KFX98890.1 - 2.1e-21 76.8 0.0 2.7e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KFX98890.1 - 8.6e-21 74.8 0.0 1.1e-20 74.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Glyco_hydro_61 PF03443.9 KFX98891.1 - 1e-68 231.4 1.2 1.5e-68 230.8 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Aminotran_4 PF01063.14 KFX98891.1 - 2.2e-22 79.6 0.0 2.9e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV CSD PF00313.17 KFX98891.1 - 0.033 13.9 0.0 0.075 12.8 0.0 1.5 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain Nif11 PF07862.6 KFX98891.1 - 0.23 11.4 0.0 0.56 10.1 0.0 1.7 1 0 0 1 1 1 0 Nitrogen fixation protein of unknown function TFIID-18kDa PF02269.11 KFX98894.1 - 5.8e-20 70.9 0.0 1.5e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit BTB PF00651.26 KFX98894.1 - 3.3e-08 33.5 0.1 1.2e-07 31.7 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain Bromo_TP PF07524.8 KFX98894.1 - 0.0078 15.9 0.0 0.3 10.8 0.0 2.5 2 0 0 2 2 2 1 Bromodomain associated DUF1242 PF06842.7 KFX98895.1 - 7.6e-14 50.9 0.6 1.5e-13 50.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1242) DUF2365 PF10157.4 KFX98896.1 - 0.081 12.8 0.1 0.75 9.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2365) Ribosom_S12_S23 PF00164.20 KFX98897.1 - 9.4e-40 134.8 0.1 1.2e-39 134.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 JAB PF01398.16 KFX98899.1 - 6.8e-17 61.2 0.0 1.1e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KFX98899.1 - 8.8e-15 54.7 0.1 1.4e-14 54.1 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF3113 PF11310.3 KFX98899.1 - 0.041 13.5 0.1 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3113) FoP_duplication PF13865.1 KFX98899.1 - 6.1 7.3 14.9 10 6.6 10.3 1.3 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF1253 PF06862.7 KFX98900.1 - 1.8e-167 557.2 0.0 2.3e-167 556.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DEAD PF00270.24 KFX98900.1 - 5.4e-05 22.7 0.0 0.0016 17.9 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF3347 PF11827.3 KFX98900.1 - 0.26 11.2 7.2 5.4 6.9 4.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) BLVR PF06375.6 KFX98900.1 - 0.56 10.0 13.2 0.036 13.8 3.6 2.3 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Nop14 PF04147.7 KFX98900.1 - 1.4 6.7 18.0 3.5 5.4 12.5 1.6 1 0 0 1 1 1 0 Nop14-like family TPT PF03151.11 KFX98902.1 - 1.6e-25 89.5 8.9 1.6e-25 89.5 6.1 2.6 3 1 0 3 3 3 1 Triose-phosphate Transporter family EmrE PF13536.1 KFX98902.1 - 0.012 15.7 1.4 0.012 15.7 1.0 4.4 3 1 1 4 4 4 0 Multidrug resistance efflux transporter UAA PF08449.6 KFX98902.1 - 0.014 14.3 17.4 0.031 13.1 8.9 3.0 1 1 1 2 2 2 0 UAA transporter family EamA PF00892.15 KFX98902.1 - 0.15 12.1 25.7 0.37 10.8 4.5 4.0 3 1 0 4 4 4 0 EamA-like transporter family RskA PF10099.4 KFX98902.1 - 0.18 11.5 0.7 0.35 10.5 0.0 1.7 2 0 0 2 2 2 0 Anti-sigma-K factor rskA NAD_binding_8 PF13450.1 KFX98903.1 - 1.5e-09 37.7 0.1 4.7e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KFX98903.1 - 2.1e-05 24.6 0.1 0.00026 21.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KFX98903.1 - 6.8e-05 22.1 0.0 0.00024 20.3 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 KFX98903.1 - 0.0015 18.4 0.0 0.027 14.3 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFX98903.1 - 0.02 13.9 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KFX98903.1 - 0.033 13.2 0.1 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 KFX98903.1 - 0.042 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain FAD_oxidored PF12831.2 KFX98903.1 - 0.074 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DAO PF01266.19 KFX98903.1 - 0.085 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KFX98903.1 - 0.13 12.0 0.2 0.37 10.5 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding WD40 PF00400.27 KFX98904.1 - 4.1e-39 131.0 5.9 2.5e-14 52.5 0.0 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat PD40 PF07676.7 KFX98904.1 - 0.00036 20.1 0.2 0.18 11.5 0.0 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat gag_pre-integrs PF13976.1 KFX98904.1 - 0.0085 15.7 0.1 33 4.2 0.0 3.9 4 0 0 4 4 4 1 GAG-pre-integrase domain DUF1258 PF06869.7 KFX98904.1 - 0.092 11.8 0.0 2.1 7.3 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) Septin PF00735.13 KFX98907.1 - 2.3e-37 128.5 0.7 8.4e-37 126.7 0.0 1.8 2 0 0 2 2 2 1 Septin BCDHK_Adom3 PF10436.4 KFX98908.1 - 2.6e-48 163.6 0.3 4.7e-48 162.8 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KFX98908.1 - 3.4e-11 42.8 0.0 2e-10 40.3 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KFX98908.1 - 0.0012 18.4 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 KFX98908.1 - 0.077 12.7 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain USP7_ICP0_bdg PF12436.3 KFX98909.1 - 1.5e-77 260.1 0.6 2.6e-76 256.1 0.2 3.0 2 1 1 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 KFX98909.1 - 3e-74 249.0 1.9 9.5e-71 237.5 0.4 3.2 3 0 0 3 3 3 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 KFX98909.1 - 1.9e-54 184.5 2.6 3.1e-54 183.9 1.8 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFX98909.1 - 2.4e-28 99.4 0.2 4.6e-28 98.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KFX98909.1 - 1.7e-12 47.6 0.9 3.6e-11 43.3 0.0 3.1 2 1 0 2 2 2 1 MATH domain YukD PF08817.5 KFX98909.1 - 0.015 15.8 0.0 0.076 13.5 0.0 2.3 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD EMP24_GP25L PF01105.19 KFX98910.1 - 2.4e-45 154.4 3.3 2.7e-45 154.3 2.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD KAP_NTPase PF07693.9 KFX98910.1 - 0.045 12.7 0.4 0.058 12.3 0.2 1.1 1 0 0 1 1 1 0 KAP family P-loop domain Bundlin PF05307.6 KFX98910.1 - 0.075 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Bundlin SKIP_SNW PF02731.10 KFX98911.1 - 4.4e-68 227.7 6.0 4.4e-68 227.7 4.2 2.3 2 0 0 2 2 2 1 SKIP/SNW domain SR-25 PF10500.4 KFX98911.1 - 0.11 11.9 20.9 0.2 11.0 14.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4603 PF15376.1 KFX98911.1 - 0.21 8.7 15.1 0.28 8.3 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) FAM60A PF15396.1 KFX98911.1 - 4.5 6.9 9.5 10 5.7 6.6 1.6 1 0 0 1 1 1 0 Protein Family FAM60A Tim17 PF02466.14 KFX98912.1 - 6.3e-48 162.0 7.4 6.3e-48 162.0 5.1 1.8 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF4048 PF13257.1 KFX98913.1 - 1.9e-12 47.3 4.6 1.9e-12 47.3 3.2 3.9 2 1 1 3 3 3 2 Domain of unknown function (DUF4048) Ribosomal_L29 PF00831.18 KFX98913.1 - 0.33 10.6 3.6 0.74 9.5 2.5 1.6 1 0 0 1 1 1 0 Ribosomal L29 protein DNA_ligase_A_N PF04675.9 KFX98914.1 - 1.6e-10 41.0 0.0 2.4e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 DNA ligase N terminus Bac_rhodopsin PF01036.13 KFX98916.1 - 6.1e-47 159.7 23.1 7.5e-47 159.4 16.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF2818 PF10993.3 KFX98916.1 - 0.088 13.3 1.0 0.088 13.3 0.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2818) CTD_bind PF04818.8 KFX98917.1 - 4.9e-08 33.0 0.1 1.4e-07 31.6 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF1777 PF08648.7 KFX98917.1 - 0.017 14.8 27.4 0.031 14.0 19.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF605 PF04652.11 KFX98917.1 - 0.02 14.3 23.5 0.038 13.4 16.3 1.4 1 1 0 1 1 1 0 Vta1 like LLC1 PF14945.1 KFX98917.1 - 0.022 15.0 0.9 0.062 13.6 0.3 2.0 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein APC_CDC26 PF10471.4 KFX98918.1 - 0.044 14.5 0.8 0.066 13.9 0.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Exo_endo_phos PF03372.18 KFX98919.1 - 2e-24 86.9 0.3 3.4e-24 86.1 0.2 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BBS2_Mid PF14783.1 KFX98919.1 - 0.031 14.0 0.1 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region CoA_transf_3 PF02515.12 KFX98920.1 - 5e-52 175.9 0.0 6.5e-52 175.5 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Dynamin_M PF01031.15 KFX98921.1 - 1.3e-105 352.3 1.5 4.3e-105 350.7 0.0 2.1 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 KFX98921.1 - 1.4e-55 187.6 0.0 2.6e-55 186.7 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KFX98921.1 - 8.4e-30 102.5 6.1 1.8e-29 101.4 4.2 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KFX98921.1 - 0.00096 19.0 1.4 0.01 15.7 0.2 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KFX98921.1 - 0.0034 17.8 0.0 0.034 14.6 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein PfkB PF00294.19 KFX98922.1 - 5.1e-49 167.0 1.3 6.3e-49 166.7 0.9 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase WD40 PF00400.27 KFX98923.1 - 7.1e-33 111.2 13.4 3.8e-08 32.9 0.3 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KFX98923.1 - 6.4e-05 22.7 0.1 0.15 11.7 0.0 3.2 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A CLTH PF10607.4 KFX98923.1 - 0.00011 21.8 0.1 0.00024 20.7 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain PD40 PF07676.7 KFX98923.1 - 0.0039 16.8 0.0 16 5.2 0.0 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat ATP-synt_ab PF00006.20 KFX98924.1 - 2.6e-113 376.8 0.0 4e-113 376.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFX98924.1 - 2.1e-19 70.0 0.3 4.4e-19 69.0 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KFX98924.1 - 2.7e-15 56.3 4.5 8.7e-15 54.6 3.3 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain NMT1 PF09084.6 KFX98925.1 - 8.5e-07 28.7 0.0 1.6e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 NMT1/THI5 like Phosphonate-bd PF12974.2 KFX98925.1 - 0.00079 18.8 0.0 0.0016 17.8 0.0 1.6 1 1 1 2 2 2 1 ABC transporter, phosphonate, periplasmic substrate-binding protein SBP_bac_3 PF00497.15 KFX98925.1 - 0.0038 16.5 0.0 0.31 10.2 0.0 2.6 2 1 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 SBP_bac_11 PF13531.1 KFX98925.1 - 0.032 13.8 0.0 0.067 12.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein LysR_substrate PF03466.15 KFX98925.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain UQ_con PF00179.21 KFX98926.1 - 4.9e-51 171.8 0.0 5.5e-51 171.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Sec63 PF02889.11 KFX98938.1 - 3.4e-143 476.5 0.0 7.1e-90 301.4 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KFX98938.1 - 1.3e-52 177.6 0.2 3.6e-28 98.1 0.3 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX98938.1 - 1.9e-16 59.6 0.0 8.5e-07 28.7 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 KFX98938.1 - 7.6e-14 51.9 0.0 5.2e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KFX98938.1 - 2.6e-07 30.8 0.7 0.042 13.9 0.0 3.5 3 2 0 3 3 3 2 AAA domain AAA_19 PF13245.1 KFX98938.1 - 5.4e-07 29.2 0.2 0.01 15.5 0.0 3.1 2 0 0 2 2 2 2 Part of AAA domain AAA PF00004.24 KFX98938.1 - 0.00013 22.2 0.0 1.4 9.1 0.0 4.5 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.18 KFX98938.1 - 0.0003 19.6 0.0 0.037 12.8 0.0 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain IstB_IS21 PF01695.12 KFX98938.1 - 0.0017 17.7 0.3 4.8 6.5 0.0 3.4 4 0 0 4 4 4 2 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 KFX98938.1 - 0.0039 16.6 0.1 0.45 9.9 0.1 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 KFX98938.1 - 0.0079 15.6 0.0 3.6 6.9 0.0 3.4 4 0 0 4 4 4 1 AAA-like domain PhoH PF02562.11 KFX98938.1 - 0.013 14.7 0.0 2.2 7.4 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein GAD-like PF08887.6 KFX98938.1 - 0.035 14.1 0.0 0.56 10.2 0.0 2.5 2 0 0 2 2 2 0 GAD-like domain DUF3586 PF12131.3 KFX98939.1 - 0.048 13.7 3.2 0.072 13.1 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) FSH1 PF03959.8 KFX98940.1 - 2.9e-31 108.5 0.0 8.4e-31 107.0 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Reprolysin_5 PF13688.1 KFX98941.1 - 0.02 14.8 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 TFIIB PF00382.14 KFX98942.1 - 5.5e-05 22.8 0.0 0.2 11.4 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_N PF00134.18 KFX98942.1 - 5.7e-05 22.6 0.1 0.02 14.4 0.0 2.5 2 1 0 2 2 2 2 Cyclin, N-terminal domain ETF PF01012.16 KFX98943.1 - 2.9e-36 124.6 0.1 3.7e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Lipoprotein_3 PF00938.12 KFX98943.1 - 0.019 14.7 0.2 0.047 13.4 0.0 1.7 2 0 0 2 2 2 0 Lipoprotein Glyco_hydro_76 PF03663.9 KFX98946.1 - 8.2e-144 479.5 15.6 1.4e-114 383.3 10.7 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 DUF1517 PF07466.6 KFX98946.1 - 0.077 11.9 1.3 0.12 11.2 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Glyco_hydro_88 PF07470.8 KFX98946.1 - 1.2 8.1 9.8 0.12 11.4 0.4 2.7 2 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 Pyr_redox_2 PF07992.9 KFX98947.1 - 4.9e-18 65.7 0.1 6.4e-18 65.3 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFX98947.1 - 1.6e-06 27.9 1.1 0.059 13.1 0.0 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KFX98947.1 - 3.1e-05 22.9 0.8 0.00067 18.6 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KFX98947.1 - 0.00019 20.4 1.5 0.00091 18.2 0.0 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFX98947.1 - 0.00024 19.6 0.2 0.017 13.5 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 KFX98947.1 - 0.0012 18.9 0.3 0.15 12.0 0.1 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFX98947.1 - 0.0016 17.5 1.1 0.0026 16.8 0.5 1.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KFX98947.1 - 0.0027 17.7 0.0 0.0055 16.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFX98947.1 - 0.0064 15.6 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 KFX98947.1 - 0.012 14.4 4.6 0.12 11.2 0.7 2.6 2 1 1 3 3 3 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KFX98947.1 - 0.015 14.2 0.1 0.17 10.7 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein vMSA PF00695.14 KFX98948.1 - 0.0016 17.7 1.7 0.0021 17.3 1.2 1.1 1 0 0 1 1 1 1 Major surface antigen from hepadnavirus SKG6 PF08693.5 KFX98948.1 - 0.016 14.5 0.2 0.034 13.4 0.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Trypan_PARP PF05887.6 KFX98948.1 - 0.023 14.4 8.4 0.038 13.8 5.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CTV_P6 PF06706.6 KFX98948.1 - 0.027 13.9 0.8 0.054 12.9 0.5 1.4 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein Rax2 PF12768.2 KFX98948.1 - 0.082 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF912 PF06024.7 KFX98948.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TMEM154 PF15102.1 KFX98948.1 - 0.7 9.5 4.5 2 8.1 3.1 1.7 1 1 0 1 1 1 0 TMEM154 protein family DUF566 PF04484.7 KFX98948.1 - 5.4 6.4 13.3 7.5 5.9 9.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF1517 PF07466.6 KFX98949.1 - 0.0086 15.1 2.0 0.012 14.5 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) Podoplanin PF05808.6 KFX98949.1 - 0.015 14.8 3.8 0.026 14.0 2.6 1.4 1 0 0 1 1 1 0 Podoplanin Adeno_E3_CR2 PF02439.10 KFX98949.1 - 0.045 13.2 0.3 0.082 12.4 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF515 PF04415.7 KFX98949.1 - 2.5 6.2 9.7 3.4 5.7 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) MFS_1 PF07690.11 KFX98950.1 - 3.2e-22 78.7 41.5 3.2e-22 78.7 28.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily GtrA PF04138.9 KFX98950.1 - 5.9 6.8 21.2 1.4 8.8 6.1 4.2 2 2 1 3 3 3 0 GtrA-like protein Methyltransf_2 PF00891.13 KFX98951.1 - 1.5e-13 50.4 0.0 2.1e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KFX98951.1 - 0.13 12.8 0.0 0.45 11.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Cellulase PF00150.13 KFX98952.1 - 2e-14 53.4 5.8 3e-14 52.9 4.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2183 PF09949.4 KFX98954.1 - 9e-31 105.7 0.0 1.9e-30 104.7 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Piwi PF02171.12 KFX98955.1 - 2.9e-71 239.9 1.3 4.3e-71 239.3 0.9 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KFX98955.1 - 7.9e-13 47.8 0.4 2.4e-12 46.3 0.3 1.7 1 1 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KFX98955.1 - 1.1e-12 47.1 0.0 2.2e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Suf PF05843.9 KFX98956.1 - 4.8e-81 272.5 0.6 3.1e-78 263.3 0.0 2.8 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 KFX98956.1 - 0.00071 19.9 0.2 0.28 11.9 0.0 4.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFX98956.1 - 0.0017 18.9 0.0 0.047 14.3 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat HAT PF02184.11 KFX98956.1 - 0.0069 16.1 0.1 0.42 10.3 0.1 2.6 2 0 0 2 2 2 1 HAT (Half-A-TPR) repeat PP28 PF10252.4 KFX98957.1 - 9e-29 99.3 15.2 9e-29 99.3 10.6 3.0 2 1 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 Glyco_tranf_2_4 PF13704.1 KFX98994.1 - 1.7e-10 41.0 1.5 3.1e-10 40.2 1.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.22 KFX98994.1 - 1.2e-07 31.3 0.7 3.5e-07 29.8 0.5 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 92 Citrate_synt PF00285.16 KFX98995.1 - 5.9e-100 334.4 0.0 7e-100 334.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase LuxE PF04443.7 KFX98996.1 - 0.032 12.9 0.0 0.032 12.9 0.0 1.1 1 0 0 1 1 1 0 Acyl-protein synthetase, LuxE SIR2 PF02146.12 KFX98997.1 - 3.9e-59 199.3 0.0 7.1e-59 198.5 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 KFX98997.1 - 5.8e-05 22.6 0.0 9.7e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 KFX98997.1 - 0.081 12.6 0.2 6.3 6.5 0.1 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain FUSC_2 PF13515.1 KFX98998.1 - 1.3e-09 38.0 26.4 2.2e-07 30.8 5.6 2.6 2 0 0 2 2 2 2 Fusaric acid resistance protein-like DUF2422 PF10337.4 KFX98998.1 - 2.6e-07 29.7 9.0 8e-06 24.9 0.5 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KFX98998.1 - 4.9e-07 29.6 0.0 1.1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) ALMT PF11744.3 KFX98998.1 - 8.7e-06 24.6 1.8 8.7e-06 24.6 1.3 2.1 2 0 0 2 2 2 1 Aluminium activated malate transporter FUSC PF04632.7 KFX98998.1 - 0.00039 19.0 9.3 0.00039 19.0 6.5 3.1 3 0 0 3 3 3 2 Fusaric acid resistance protein family Bac_export_1 PF01311.15 KFX98998.1 - 0.027 13.7 1.4 0.1 11.8 0.5 2.1 2 0 0 2 2 2 0 Bacterial export proteins, family 1 adh_short_C2 PF13561.1 KFX98999.1 - 1.5e-33 116.5 0.0 1.7e-33 116.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFX98999.1 - 2.7e-33 115.2 1.6 4.2e-33 114.6 1.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX98999.1 - 1.3e-15 57.5 0.5 2.2e-15 56.7 0.4 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFX98999.1 - 5.1e-07 29.8 0.4 1.9e-06 27.9 0.3 2.0 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 KFX98999.1 - 0.00066 18.8 0.0 0.00096 18.3 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.14 KFX98999.1 - 0.00067 18.7 0.2 0.0014 17.7 0.1 1.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 KFX98999.1 - 0.00079 18.9 0.0 0.21 10.9 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KFX98999.1 - 0.0046 16.7 0.1 0.01 15.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 KFX98999.1 - 0.013 15.5 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 KFX98999.1 - 0.13 11.2 0.8 0.23 10.4 0.2 1.6 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 KFX99001.1 - 3.3e-29 102.0 0.1 1.6e-17 63.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KFX99001.1 - 9e-06 24.8 0.0 0.34 9.7 0.0 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein SE PF08491.5 KFX99001.1 - 1e-05 24.5 0.0 0.0017 17.2 0.0 2.4 2 0 0 2 2 2 2 Squalene epoxidase DAO PF01266.19 KFX99001.1 - 2e-05 23.6 0.2 0.049 12.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KFX99001.1 - 0.00044 18.9 0.0 0.11 11.1 0.0 2.8 2 1 0 3 3 3 1 Tryptophan halogenase Amino_oxidase PF01593.19 KFX99001.1 - 0.00048 19.3 0.0 0.00075 18.6 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 KFX99001.1 - 0.0013 18.8 0.0 0.0048 16.9 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFX99001.1 - 0.0015 18.9 0.0 1.1 9.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX99001.1 - 0.0025 17.7 0.3 0.0079 16.1 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KFX99001.1 - 0.0045 16.7 0.4 0.53 10.0 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 KFX99001.1 - 0.0052 15.2 0.0 0.35 9.2 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 KFX99001.1 - 0.015 15.1 0.1 0.034 14.0 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFX99001.1 - 0.069 11.9 0.1 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain DIOX_N PF14226.1 KFX99002.1 - 1.5e-14 54.4 0.0 2.6e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KFX99002.1 - 2.1e-12 47.2 0.0 3.4e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 KFX99003.1 - 1e-30 106.6 32.8 1e-30 106.6 22.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cupin_2 PF07883.6 KFX99004.1 - 8.4e-11 41.2 0.6 8.4e-11 41.2 0.4 1.6 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 KFX99004.1 - 9.1e-07 28.4 0.0 1.1e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 KFX99004.1 - 0.00081 19.0 0.1 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain JmjC PF02373.17 KFX99004.1 - 0.0026 17.9 0.1 0.016 15.4 0.1 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase GPI PF06560.6 KFX99004.1 - 0.031 13.2 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) FdtA PF05523.6 KFX99004.1 - 0.14 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal DIOX_N PF14226.1 KFX99005.1 - 6e-19 68.6 0.0 1.2e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KFX99005.1 - 7e-13 48.7 0.0 1.2e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily OPT PF03169.10 KFX99006.1 - 6.1e-178 593.1 45.3 7.1e-178 592.9 31.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein BofA PF07441.6 KFX99006.1 - 4.5 7.3 19.2 0.35 10.8 7.7 2.9 2 0 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA adh_short PF00106.20 KFX99010.1 - 6.6e-26 91.2 0.0 1.2e-25 90.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX99010.1 - 3.7e-25 89.0 0.0 5e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX99010.1 - 6.2e-07 29.2 0.0 1.8e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 KR domain TPMT PF05724.6 KFX99011.1 - 2.9e-26 92.2 0.0 4.2e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 KFX99011.1 - 2.1e-06 28.2 0.0 3.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX99011.1 - 6.3e-05 22.9 0.0 0.00015 21.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX99011.1 - 0.0001 21.9 0.0 0.00059 19.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX99011.1 - 0.0024 18.2 0.0 0.0041 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX99011.1 - 0.0035 17.0 0.0 0.005 16.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 KFX99011.1 - 0.018 14.2 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB OTU PF02338.14 KFX99012.1 - 5.9e-18 65.6 0.0 5.9e-18 65.6 0.0 2.1 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KFX99012.1 - 8.2e-05 22.0 0.2 0.045 13.0 0.0 2.9 2 1 1 3 3 3 2 Peptidase C65 Otubain AMP-binding PF00501.23 KFX99013.1 - 3e-74 249.9 0.0 4.1e-74 249.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX99013.1 - 4.3e-09 37.2 0.0 4.9e-08 33.8 0.0 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Sox_C_TAD PF12067.3 KFX99013.1 - 0.067 13.3 1.2 0.2 11.8 0.8 1.8 1 1 1 2 2 2 0 Sox C-terminal transactivation domain Ras PF00071.17 KFX99014.1 - 6.1e-52 175.2 0.0 8.6e-52 174.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX99014.1 - 5.5e-17 62.3 0.0 2.6e-15 56.9 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFX99014.1 - 0.00036 19.8 0.0 0.00087 18.5 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KFX99014.1 - 0.013 15.4 0.0 0.016 15.1 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KFX99014.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 KFX99014.1 - 0.049 12.9 0.1 0.48 9.6 0.0 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B AAA_25 PF13481.1 KFX99014.1 - 0.082 12.2 0.2 0.21 10.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 KFX99014.1 - 0.12 11.3 0.0 0.36 9.8 0.0 1.8 3 0 0 3 3 3 0 Septin Opy2 PF09463.5 KFX99015.1 - 2.4e-07 30.7 25.3 4e-07 30.0 17.5 1.4 1 0 0 1 1 1 1 Opy2 protein Syndecan PF01034.15 KFX99015.1 - 0.0019 17.8 0.6 0.0033 17.0 0.0 1.7 2 0 0 2 2 2 1 Syndecan domain OAD_gamma PF04277.8 KFX99015.1 - 4 7.8 9.9 47 4.4 0.8 3.3 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain zf-C2H2_3 PF13878.1 KFX99017.1 - 0.044 13.3 0.6 6.2 6.4 0.1 2.8 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Vac7 PF12751.2 KFX99018.1 - 1.9e-122 408.8 2.1 1.9e-122 408.8 1.4 1.8 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 LEA_2 PF03168.8 KFX99018.1 - 0.044 14.1 0.0 2 8.8 0.0 2.6 2 0 0 2 2 2 0 Late embryogenesis abundant protein Ima1_N PF09779.4 KFX99023.1 - 2.2e-40 138.1 4.9 4e-40 137.3 3.4 1.5 1 0 0 1 1 1 1 Ima1 N-terminal domain DUF1430 PF07242.6 KFX99023.1 - 0.2 11.7 1.0 0.24 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) DUF2296 PF10058.4 KFX99023.1 - 0.37 10.5 2.6 12 5.7 0.5 2.7 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Rep_fac-A_C PF08646.5 KFX99023.1 - 2.8 7.6 5.4 8.9 6.0 1.4 2.3 2 0 0 2 2 2 0 Replication factor-A C terminal domain HSP70 PF00012.15 KFX99025.1 - 2.1e-78 263.7 2.3 2.5e-78 263.5 1.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFX99025.1 - 1.7e-11 43.3 0.1 3.2e-11 42.4 0.0 1.4 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KFX99025.1 - 0.16 11.8 2.9 1.9 8.3 0.1 2.6 2 1 0 2 2 2 0 Cell division protein FtsA Lipase_3 PF01764.20 KFX99030.1 - 6.1e-06 25.8 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 KFX99030.1 - 0.05 13.3 0.0 0.082 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.2 KFX99030.1 - 0.05 13.3 0.0 0.095 12.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pkinase PF00069.20 KFX99037.1 - 3.6e-56 190.2 0.0 5.2e-56 189.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX99037.1 - 4.8e-18 65.1 0.0 7.6e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX99037.1 - 3.7e-06 26.1 0.0 7.2e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFX99037.1 - 9.9e-06 25.4 1.0 0.039 13.6 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KFX99037.1 - 0.00047 19.2 0.1 0.00094 18.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KFX99037.1 - 0.058 12.7 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 RIO1 family RasGAP PF00616.14 KFX99041.1 - 2.4e-42 144.8 0.0 6.9e-42 143.3 0.0 1.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 KFX99041.1 - 0.15 11.8 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 C2 domain MRP-L20 PF12824.2 KFX99043.1 - 5.5e-58 195.5 3.1 6.3e-58 195.3 2.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Tyr_Deacylase PF02580.11 KFX99044.1 - 6.5e-45 152.6 0.3 7.3e-45 152.5 0.2 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.10 KFX99045.1 - 5.7e-100 333.3 24.9 8.6e-100 332.8 17.2 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 KFX99045.1 - 2.7e-39 134.1 9.7 8.3e-39 132.5 6.8 1.9 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Cep57_MT_bd PF06657.8 KFX99045.1 - 0.02 14.8 7.1 0.036 13.9 0.7 2.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF2373 PF10180.4 KFX99045.1 - 0.021 14.3 2.2 0.046 13.2 1.5 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Syntaxin_2 PF14523.1 KFX99045.1 - 0.16 11.9 10.3 0.16 11.9 3.3 3.1 3 0 0 3 3 3 0 Syntaxin-like protein Snapin_Pallidin PF14712.1 KFX99045.1 - 0.17 12.1 8.7 0.87 9.9 0.1 2.6 2 0 0 2 2 2 0 Snapin/Pallidin DUF1192 PF06698.6 KFX99045.1 - 1.4 8.7 7.4 0.2 11.4 0.9 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Syntaxin PF00804.20 KFX99045.1 - 1.5 9.0 17.8 0.28 11.3 4.2 3.0 3 0 0 3 3 3 0 Syntaxin Poty_PP PF08440.5 KFX99045.1 - 1.8 7.5 7.7 0.087 11.8 1.2 1.8 2 0 0 2 2 2 0 Potyviridae polyprotein Sec5 PF15469.1 KFX99045.1 - 9 5.9 12.0 0.68 9.6 1.7 2.9 3 0 0 3 3 3 0 Exocyst complex component Sec5 Aminotran_4 PF01063.14 KFX99046.1 - 2.3e-27 95.9 0.0 4.9e-27 94.8 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class IV Claudin_2 PF13903.1 KFX99048.1 - 0.0011 18.7 3.1 0.0018 17.9 2.2 1.3 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction FUSC_2 PF13515.1 KFX99049.1 - 3.2e-24 85.2 10.8 3.2e-24 85.2 7.5 3.3 2 1 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 KFX99049.1 - 0.0062 16.1 0.4 0.03 13.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC-like PF12805.2 KFX99049.1 - 0.0071 15.3 1.3 0.016 14.1 0.9 1.6 1 0 0 1 1 1 1 FUSC-like inner membrane protein yccS ALMT PF11744.3 KFX99049.1 - 0.022 13.4 18.1 0.25 9.9 0.0 3.8 3 1 0 4 4 4 0 Aluminium activated malate transporter DUF2628 PF10947.3 KFX99049.1 - 9.5 6.0 12.6 0.17 11.6 1.2 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2628) DNA_pol_E_B PF04042.11 KFX99050.1 - 9.7e-46 155.6 0.0 1.5e-45 155.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B PRELI PF04707.9 KFX99052.1 - 3.9e-18 65.4 0.1 3.4e-16 59.1 0.0 2.3 2 1 0 2 2 2 2 PRELI-like family tRNA-synt_1b PF00579.20 KFX99053.1 - 8.1e-20 71.1 0.0 1.9e-19 69.9 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Ras PF00071.17 KFX99057.1 - 3e-31 107.9 0.1 4e-31 107.5 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFX99057.1 - 2.5e-20 73.1 0.1 8.6e-20 71.4 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFX99057.1 - 1.4e-06 27.6 0.1 1.9e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFX99057.1 - 1.5e-05 24.2 0.2 2.1e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.6 KFX99057.1 - 0.019 13.6 0.2 3.9 6.0 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) G-alpha PF00503.15 KFX99057.1 - 0.21 10.2 0.0 0.21 10.2 0.0 2.4 1 1 2 3 3 3 0 G-protein alpha subunit GCV_H PF01597.14 KFX99058.1 - 7.8e-33 112.7 0.3 9.2e-33 112.5 0.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein PSI_PsaE PF02427.12 KFX99058.1 - 0.13 11.6 0.0 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Photosystem I reaction centre subunit IV / PsaE Porphobil_deam PF01379.15 KFX99059.1 - 3.1e-80 268.1 0.0 4.1e-80 267.7 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 KFX99059.1 - 6.6e-19 67.7 0.2 1.3e-18 66.8 0.2 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Methyltransf_23 PF13489.1 KFX99060.1 - 3.4e-22 78.8 0.0 4.9e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX99060.1 - 8.9e-10 38.9 0.0 1.8e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX99060.1 - 2.3e-08 33.7 0.0 4.3e-07 29.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX99060.1 - 4.5e-07 30.4 0.0 7.8e-06 26.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX99060.1 - 2e-06 28.1 0.0 3.5e-05 24.1 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX99060.1 - 0.00014 22.1 0.0 0.00049 20.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KFX99060.1 - 0.00073 18.6 0.0 0.0068 15.4 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 KFX99060.1 - 0.038 13.9 0.0 0.073 13.0 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 KFX99060.1 - 0.044 12.8 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KFX99060.1 - 0.18 11.1 0.0 0.54 9.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase small domain DUF1996 PF09362.5 KFX99061.1 - 4.6e-82 275.2 2.2 7.3e-82 274.5 1.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) adh_short PF00106.20 KFX99061.1 - 1.4e-15 57.5 0.0 2.5e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX99061.1 - 0.00065 19.4 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 KR domain CBM_1 PF00734.13 KFX99061.1 - 0.0024 17.4 5.0 0.0024 17.4 3.5 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain FA_hydroxylase PF04116.8 KFX99062.1 - 3.7e-14 53.1 14.3 3.7e-14 53.1 9.9 2.4 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Abhydrolase_3 PF07859.8 KFX99063.1 - 2.6e-25 89.2 0.0 3.3e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KFX99063.1 - 1.5e-09 36.9 0.0 2.2e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) DUF3780 PF12635.2 KFX99064.1 - 0.089 12.3 2.4 0.11 11.9 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3780) Glyco_hydro_18 PF00704.23 KFX99076.1 - 7.2e-20 71.7 0.0 7.7e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.23 KFX99083.1 - 1.1e-22 80.9 0.0 1.2e-22 80.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DIOX_N PF14226.1 KFX99093.1 - 3.5e-23 82.3 0.0 8.2e-23 81.1 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal WD40 PF00400.27 KFX99093.1 - 3.1e-07 30.0 7.7 0.0025 17.6 0.0 5.9 7 0 0 7 7 7 2 WD domain, G-beta repeat RNA_pol_N PF01194.12 KFX99094.1 - 2.8e-31 107.2 0.6 5.1e-31 106.4 0.4 1.4 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 KFX99094.1 - 0.074 13.1 0.2 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) ADH_N PF08240.7 KFX99096.1 - 0.27 10.9 0.0 0.54 10.0 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain F-box-like PF12937.2 KFX99097.1 - 0.0008 19.0 0.1 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX99097.1 - 0.0088 15.6 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 F-box domain Zn_clus PF00172.13 KFX99098.1 - 1.3e-08 34.6 10.9 2.4e-08 33.7 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFX99098.1 - 2.1e-07 29.8 0.5 2.8e-07 29.4 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TRI12 PF06609.8 KFX99100.1 - 1.2e-26 93.0 25.7 1.5e-26 92.8 17.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KFX99100.1 - 1.2e-21 76.8 48.0 1.2e-21 76.8 33.2 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4141 PF13605.1 KFX99100.1 - 0.04 13.1 0.6 0.15 11.2 0.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) DUF2301 PF10063.4 KFX99100.1 - 1.1 9.4 11.4 0.84 9.8 0.9 3.6 3 0 0 3 3 3 0 Uncharacterized integral membrane protein (DUF2301) p450 PF00067.17 KFX99101.1 - 4.3e-55 187.0 0.0 5.3e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 RTA1 PF04479.8 KFX99102.1 - 1.1e-33 116.6 5.7 1.8e-33 115.9 4.0 1.3 1 0 0 1 1 1 1 RTA1 like protein Fungal_trans_2 PF11951.3 KFX99103.1 - 4.8e-07 28.7 0.4 8.2e-07 27.9 0.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX99103.1 - 1.6e-06 27.8 10.0 4e-06 26.6 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MCM PF00493.18 KFX99107.1 - 1.6e-129 431.4 0.3 2.3e-129 430.9 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KFX99107.1 - 4.2e-17 62.7 0.4 3.7e-16 59.6 0.0 2.5 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFX99107.1 - 2.9e-07 29.8 0.0 4e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KFX99107.1 - 0.0023 17.5 0.0 0.0071 15.9 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KFX99107.1 - 0.051 13.0 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Nop53 PF07767.6 KFX99107.1 - 0.26 10.2 10.2 0.42 9.5 7.1 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) PfkB PF00294.19 KFX99108.1 - 2.2e-12 46.7 0.0 2.3e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 pfkB family carbohydrate kinase CAP_N PF01213.14 KFX99109.1 - 2.3e-85 286.6 21.3 6.1e-85 285.2 13.8 2.1 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 KFX99109.1 - 5.5e-59 198.0 0.7 7.8e-59 197.5 0.5 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 KFX99109.1 - 0.19 11.1 1.0 0.49 9.7 0.5 1.7 1 1 0 2 2 2 0 Tubulin binding cofactor C Ribonuclease_3 PF00636.21 KFX99111.1 - 3.6e-09 37.0 0.0 9.7e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KFX99111.1 - 2e-08 34.2 0.0 0.00031 20.7 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.20 KFX99111.1 - 0.00016 22.1 0.1 0.00049 20.6 0.0 1.9 2 0 0 2 2 2 1 Double-stranded RNA binding motif NUDE_C PF04880.8 KFX99111.1 - 0.08 13.2 0.4 0.16 12.2 0.3 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region La PF05383.12 KFX99112.1 - 1.2e-12 47.3 0.0 1.8e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 KFX99112.1 - 9.9e-09 34.7 0.2 2.2e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX99112.1 - 4.7e-08 32.8 0.0 8.8e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2946 PF11162.3 KFX99113.1 - 0.089 12.9 0.1 0.089 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) S4 PF01479.20 KFX99114.1 - 4.5e-17 61.2 0.0 7.7e-17 60.4 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 KFX99114.1 - 0.0079 15.7 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 S4 domain FancD2 PF14631.1 KFX99114.1 - 0.018 12.1 2.0 0.024 11.7 1.4 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RR_TM4-6 PF06459.7 KFX99114.1 - 0.21 11.4 4.4 0.36 10.6 3.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4551 PF15087.1 KFX99114.1 - 0.71 8.1 4.3 0.96 7.7 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) HSP70 PF00012.15 KFX99114.1 - 1.1 7.0 9.1 1.6 6.5 6.3 1.1 1 0 0 1 1 1 0 Hsp70 protein DUF3323 PF11796.3 KFX99114.1 - 5.4 6.2 15.6 0.34 10.1 6.9 1.8 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) INCENP_ARK-bind PF03941.10 KFX99115.1 - 7.3e-16 57.7 0.0 3.1e-15 55.7 0.0 2.2 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region HC2 PF07382.6 KFX99115.1 - 0.0012 18.7 22.7 0.0012 18.7 15.8 3.2 3 0 0 3 3 3 1 Histone H1-like nucleoprotein HC2 Phosphoesterase PF04185.9 KFX99116.1 - 5.3e-66 223.3 1.2 1e-65 222.4 0.8 1.4 1 1 0 1 1 1 1 Phosphoesterase family MFS_1 PF07690.11 KFX99117.1 - 4.7e-30 104.5 56.6 2.4e-29 102.1 39.2 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX99117.1 - 1.6e-07 30.2 17.1 1.6e-07 30.2 11.9 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter Glyco_hydro_3 PF00933.16 KFX99127.1 - 3.1e-97 325.1 0.0 4.9e-97 324.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFX99127.1 - 1.9e-58 197.6 3.3 2.3e-58 197.4 0.7 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFX99127.1 - 9.3e-12 44.7 0.0 2e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain TauD PF02668.11 KFX99128.1 - 5.5e-40 137.6 0.0 8.4e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 KFX99128.1 - 2.1e-07 31.2 0.0 4.3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) DUF932 PF06067.6 KFX99128.1 - 0.066 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF932) Lactamase_B PF00753.22 KFX99130.1 - 3e-16 59.6 0.0 9.9e-16 57.9 0.0 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFX99130.1 - 6.5e-05 22.5 0.0 0.0001 21.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PABP PF00658.13 KFX99131.1 - 2.8e-25 87.7 3.4 1.1e-18 66.6 0.3 2.7 2 0 0 2 2 2 2 Poly-adenylate binding protein, unique domain RINGv PF12906.2 KFX99131.1 - 6.6e-16 58.0 8.8 1.1e-15 57.3 6.1 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KFX99131.1 - 0.043 13.6 7.9 0.074 12.8 5.5 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING_4 PF14570.1 KFX99131.1 - 2.8 7.5 6.7 4.8 6.8 4.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 KFX99131.1 - 7.6 6.5 5.8 15 5.6 4.0 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain MCR_C PF04609.7 KFX99132.1 - 1.3 7.7 4.6 0.73 8.5 0.1 2.4 3 0 0 3 3 3 0 Methyl-coenzyme M reductase operon protein C DUF3268 PF11672.3 KFX99133.1 - 0.0018 18.2 0.7 1.7 8.7 0.0 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF3268) rve PF00665.21 KFX99136.1 - 2.9e-20 72.5 0.0 5.9e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 KFX99136.1 - 0.019 14.5 0.0 0.044 13.2 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain VESA1_N PF12785.2 KFX99136.1 - 0.13 11.2 8.2 0.2 10.5 5.7 1.2 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 WD40 PF00400.27 KFX99139.1 - 3.9e-172 552.8 55.1 1.1e-14 53.6 0.1 14.0 14 0 0 14 14 14 13 WD domain, G-beta repeat HET PF06985.6 KFX99139.1 - 1.9e-21 76.6 5.4 1.7e-18 67.1 0.2 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF1258 PF06869.7 KFX99139.1 - 4.2e-12 45.6 9.0 0.72 8.8 0.0 9.4 3 2 8 11 11 11 4 Protein of unknown function (DUF1258) Nup160 PF11715.3 KFX99139.1 - 4.4e-11 41.6 27.2 0.0046 15.1 0.4 8.7 1 1 9 10 10 10 4 Nucleoporin Nup120/160 Proteasome_A_N PF10584.4 KFX99139.1 - 6.5e-09 34.9 8.0 3.4 7.0 0.0 9.0 9 0 0 9 9 9 1 Proteasome subunit A N-terminal signature NACHT PF05729.7 KFX99139.1 - 5.3e-08 32.6 0.0 1.3e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Cytochrom_D1 PF02239.11 KFX99139.1 - 1.7e-07 29.8 9.5 0.018 13.3 0.1 5.8 2 1 4 6 6 6 4 Cytochrome D1 heme domain PD40 PF07676.7 KFX99139.1 - 5e-07 29.2 13.2 27 4.5 0.0 9.5 10 0 0 10 10 9 0 WD40-like Beta Propeller Repeat AAA_22 PF13401.1 KFX99139.1 - 0.0047 17.0 0.0 0.016 15.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFX99139.1 - 0.011 15.7 0.0 0.047 13.6 0.0 2.1 2 0 0 2 2 1 0 AAA ATPase domain AAA_17 PF13207.1 KFX99139.1 - 0.051 14.3 0.0 0.18 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KFX99139.1 - 0.085 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase CPSF_A PF03178.10 KFX99139.1 - 0.13 11.3 0.0 2.8 6.9 0.0 2.3 2 0 0 2 2 2 0 CPSF A subunit region AAA_18 PF13238.1 KFX99139.1 - 0.13 12.5 0.0 0.42 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain Glyoxal_oxid_N PF07250.6 KFX99139.1 - 0.28 10.2 4.8 13 4.7 0.0 3.9 2 1 2 4 4 4 0 Glyoxal oxidase N-terminus Sugar_tr PF00083.19 KFX99141.1 - 5.9e-84 282.2 17.1 6.8e-84 282.0 11.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX99141.1 - 5.5e-29 100.9 23.3 3e-24 85.3 13.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX99141.1 - 2.1e-05 23.1 18.9 0.00029 19.3 0.6 2.8 2 2 0 2 2 2 2 MFS/sugar transport protein Fork_head PF00250.13 KFX99157.1 - 2.8e-23 81.7 0.5 1.9e-22 79.1 0.1 2.4 3 0 0 3 3 3 1 Fork head domain FHA PF00498.21 KFX99157.1 - 1.3e-09 38.0 0.1 4.8e-09 36.2 0.1 1.9 2 0 0 2 2 2 1 FHA domain BAG PF02179.11 KFX99159.1 - 2.2e-19 69.3 0.0 4.9e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 KFX99159.1 - 0.00018 20.8 0.0 0.00031 20.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KFX99159.1 - 0.0069 16.5 0.1 0.015 15.4 0.1 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.3 KFX99159.1 - 0.085 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2201_N PF13203.1 KFX99159.1 - 0.31 10.1 2.6 0.5 9.4 1.8 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain BLVR PF06375.6 KFX99159.1 - 0.36 10.6 7.6 0.63 9.8 4.9 1.7 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Acetyltransf_1 PF00583.19 KFX99160.1 - 1.9e-10 40.6 0.0 2.7e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KFX99160.1 - 7.6e-06 25.5 0.0 1.2e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KFX99160.1 - 0.088 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.2 KFX99161.1 - 4.3e-05 23.5 0.0 0.00014 21.8 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 KFX99161.1 - 0.0012 17.8 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.15 KFX99161.1 - 0.046 13.2 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.9 KFX99161.1 - 0.16 11.2 0.1 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) T5orf172 PF10544.4 KFX99166.1 - 5.7e-19 68.3 0.1 1.2e-18 67.3 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 KFX99166.1 - 4.4e-13 49.4 0.1 9.9e-13 48.3 0.1 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Spore_coat_CotO PF14153.1 KFX99166.1 - 1.3 8.4 6.1 1.9 7.9 4.3 1.4 1 0 0 1 1 1 0 Spore coat protein CotO Glyco_hydro_15 PF00723.16 KFX99167.1 - 5.8e-47 160.2 0.0 4.4e-44 150.7 0.0 2.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 TPT PF03151.11 KFX99169.1 - 1.9e-30 105.5 5.9 1.9e-30 105.5 4.1 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family Pkinase PF00069.20 KFX99169.1 - 5.6e-25 87.9 0.0 1.1e-24 87.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX99169.1 - 0.00012 21.2 0.0 0.0075 15.3 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase EamA PF00892.15 KFX99169.1 - 0.00027 20.9 1.0 0.00027 20.9 0.7 3.0 3 0 0 3 3 3 1 EamA-like transporter family UAA PF08449.6 KFX99169.1 - 0.0046 15.9 19.3 0.0042 16.0 9.2 2.5 3 0 0 3 3 3 1 UAA transporter family LAP1C PF05609.7 KFX99169.1 - 0.027 13.1 0.5 0.04 12.6 0.3 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) YlaH PF14036.1 KFX99169.1 - 7.5 6.7 10.0 1.4 9.0 2.7 2.5 2 0 0 2 2 2 0 YlaH-like protein p450 PF00067.17 KFX99170.1 - 3e-51 174.4 0.0 4e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 KFX99170.1 - 5.8e-21 74.7 0.0 9.6e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX99170.1 - 3.1e-05 23.1 0.1 0.00068 18.7 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Fructosamin_kin PF03881.9 KFX99171.1 - 6.2e-33 114.0 0.0 8.7e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KFX99171.1 - 0.0015 18.3 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family MFS_1 PF07690.11 KFX99172.1 - 1.3e-34 119.5 37.4 2.9e-34 118.3 21.9 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily NACHT PF05729.7 KFX99172.1 - 2e-06 27.5 0.1 4.2e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.8 KFX99172.1 - 0.00012 21.8 0.0 0.00036 20.1 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.9 KFX99172.1 - 0.00021 20.6 0.0 0.00044 19.6 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) WD40 PF00400.27 KFX99172.1 - 0.00043 20.0 0.1 13 5.8 0.0 5.6 5 1 0 5 5 5 1 WD domain, G-beta repeat AAA_16 PF13191.1 KFX99172.1 - 0.00069 19.6 0.0 0.002 18.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Abhydrolase_6 PF12697.2 KFX99172.1 - 0.003 17.4 0.0 0.01 15.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family 6PGD PF00393.14 KFX99173.1 - 1e-133 445.0 0.0 1.3e-133 444.7 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KFX99173.1 - 4.8e-51 172.8 0.0 6.8e-51 172.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KFX99173.1 - 0.056 13.4 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase HIT PF01230.18 KFX99174.1 - 1.1e-14 54.6 0.1 6.6e-14 52.2 0.1 2.2 2 1 0 2 2 2 1 HIT domain DcpS_C PF11969.3 KFX99174.1 - 2e-05 24.7 0.1 0.00013 22.1 0.1 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KFX99174.1 - 0.0034 17.0 0.9 0.015 14.9 0.2 2.2 2 1 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 WD40 PF00400.27 KFX99177.1 - 3.9e-60 197.7 25.5 5.1e-11 42.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KFX99177.1 - 1.8e-05 23.1 3.2 0.087 10.9 0.1 3.7 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KFX99177.1 - 0.026 12.8 0.1 4.4 5.4 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain TAF8_C PF10406.4 KFX99178.1 - 6.6e-18 64.4 1.0 6.6e-18 64.4 0.7 2.1 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 KFX99178.1 - 1.6e-05 24.5 0.0 2.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated ORC6 PF05460.8 KFX99178.1 - 0.26 10.3 6.4 0.45 9.5 4.5 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Mitochondr_Som1 PF11093.3 KFX99179.1 - 3.9e-13 49.0 0.0 4.4e-13 48.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial export protein Som1 ABC1 PF03109.11 KFX99190.1 - 3.1e-22 78.7 0.0 7.2e-12 45.3 0.0 2.5 2 0 0 2 2 2 2 ABC1 family APH PF01636.18 KFX99190.1 - 0.011 15.5 0.9 0.044 13.5 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Cyto_heme_lyase PF01265.12 KFX99191.1 - 8.2e-75 251.7 0.1 1.3e-74 251.1 0.1 1.3 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF3446 PF11928.3 KFX99191.1 - 2.8 8.1 8.3 6.6 7.0 5.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) TPT PF03151.11 KFX99194.1 - 1.1e-39 135.5 2.2 1.1e-39 135.5 1.6 1.8 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KFX99194.1 - 1.6e-09 37.1 11.0 8.4e-09 34.7 7.6 1.9 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KFX99194.1 - 0.0017 18.3 32.0 0.0091 16.0 5.3 3.5 3 2 0 3 3 3 2 EamA-like transporter family PSII PF00421.14 KFX99194.1 - 0.032 12.8 0.4 0.05 12.1 0.3 1.2 1 0 0 1 1 1 0 Photosystem II protein NT-C2 PF10358.4 KFX99197.1 - 9.6e-31 106.1 0.0 1.1e-30 105.9 0.0 1.0 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins A_deamin PF02137.13 KFX99198.1 - 6.3e-64 216.4 0.0 7.5e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF904 PF06005.7 KFX99199.1 - 1.8 8.9 9.2 1.4 9.2 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF904) SF3b10 PF07189.6 KFX99200.1 - 5.9e-39 131.7 0.0 6.9e-39 131.5 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) MAGE PF01454.14 KFX99201.1 - 5.6e-42 143.2 0.0 7.7e-42 142.8 0.0 1.2 1 0 0 1 1 1 1 MAGE family ACTH_domain PF00976.13 KFX99201.1 - 0.17 11.7 1.0 0.5 10.2 0.7 1.9 1 0 0 1 1 1 0 Corticotropin ACTH domain MFS_1 PF07690.11 KFX99202.1 - 5.3e-33 114.1 28.4 8.2e-33 113.5 19.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Rad21_Rec8_N PF04825.8 KFX99202.1 - 1.5e-29 102.1 0.0 3e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KFX99202.1 - 2.6e-05 23.3 0.0 5.5e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein TRP PF06011.7 KFX99203.1 - 1.1e-101 340.6 21.8 1.8e-101 339.9 15.1 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KFX99203.1 - 2.7e-19 69.5 0.0 4.3e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 ML-like domain BTB PF00651.26 KFX99204.1 - 2.8e-30 104.5 0.1 8.4e-15 54.7 0.4 2.7 2 0 0 2 2 2 2 BTB/POZ domain Ank_5 PF13857.1 KFX99204.1 - 2.9e-07 30.5 0.0 6.7e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 KFX99204.1 - 4.9e-07 29.2 0.4 2.6e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 KFX99204.1 - 1.4e-05 25.3 0.0 3.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFX99204.1 - 3.6e-05 24.1 0.1 0.00011 22.5 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX99204.1 - 0.0012 18.8 0.0 0.0046 17.0 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Imm41 PF15583.1 KFX99204.1 - 0.022 14.5 3.8 0.12 12.1 2.6 2.1 1 1 0 1 1 1 0 Immunity protein 41 DUF3342 PF11822.3 KFX99204.1 - 0.033 13.3 0.1 0.057 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) Sterol-sensing PF12349.3 KFX99206.1 - 9.1e-43 145.3 6.4 1.9e-42 144.3 4.4 1.5 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KFX99206.1 - 9.4e-15 53.6 2.0 1.3e-14 53.0 1.4 1.1 1 0 0 1 1 1 1 Patched family WD40 PF00400.27 KFX99206.1 - 0.019 14.8 0.1 0.058 13.2 0.0 1.9 1 0 0 1 1 1 0 WD domain, G-beta repeat Sugar_tr PF00083.19 KFX99207.1 - 3.9e-84 282.8 22.0 4.4e-84 282.6 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX99207.1 - 6.1e-29 100.8 31.1 2.6e-18 65.8 10.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CDO_I PF05995.7 KFX99209.1 - 0.039 13.1 0.2 0.56 9.3 0.0 2.1 2 0 0 2 2 2 0 Cysteine dioxygenase type I MFS_1 PF07690.11 KFX99210.1 - 2.2e-33 115.4 58.7 1.4e-32 112.7 40.5 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFX99210.1 - 1.5e-07 30.0 23.8 2.1e-07 29.5 16.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3237 PF11578.3 KFX99211.1 - 8.7e-28 96.5 0.0 9.7e-28 96.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Mob1_phocein PF03637.12 KFX99212.1 - 4.6e-38 130.6 0.8 4.8e-21 75.2 0.0 2.1 2 0 0 2 2 2 2 Mob1/phocein family Leo1 PF04004.8 KFX99213.1 - 1.8e-28 99.4 0.1 1.8e-28 99.4 0.1 2.0 2 0 0 2 2 2 1 Leo1-like protein DUF1460 PF07313.7 KFX99213.1 - 0.041 13.0 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) U3_snoRNA_assoc PF08297.6 KFX99213.1 - 1.1 9.5 7.3 9.3 6.5 0.4 3.1 3 0 0 3 3 3 0 U3 snoRNA associated DUF1840 PF08895.6 KFX99213.1 - 6.1 6.9 10.0 0.19 11.7 1.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1840) CHORD PF04968.7 KFX99214.1 - 3.4e-50 168.1 18.0 7.6e-26 90.1 4.9 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 KFX99214.1 - 4.5e-16 59.1 0.0 7e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 CS domain HeLo PF14479.1 KFX99215.1 - 1e-37 130.0 0.5 9.6e-37 126.7 0.1 2.1 2 0 0 2 2 2 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.12 KFX99215.1 - 0.13 11.3 0.0 2.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase SURF4 PF02077.10 KFX99216.1 - 6e-97 324.1 5.4 7.3e-97 323.9 3.7 1.1 1 0 0 1 1 1 1 SURF4 family WH2 PF02205.15 KFX99216.1 - 1.2e-10 40.6 1.5 4.3e-10 38.8 1.1 2.1 1 0 0 1 1 1 1 WH2 motif NIR_SIR PF01077.17 KFX99217.1 - 0.0074 15.6 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain BOP1NT PF08145.7 KFX99218.1 - 1.3e-104 349.5 8.3 1.8e-104 349.0 5.7 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 KFX99218.1 - 8e-29 98.4 5.8 2.9e-11 42.7 0.1 6.4 8 0 0 8 8 8 4 WD domain, G-beta repeat Tannase PF07519.6 KFX99219.1 - 3.5e-95 319.4 0.3 4.1e-95 319.2 0.2 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 KFX99219.1 - 1.3e-06 28.4 1.1 3.1e-05 23.9 0.8 2.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFX99219.1 - 8.5e-06 25.1 0.1 0.12 11.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KFX99219.1 - 0.00052 19.6 0.1 0.0013 18.3 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX99219.1 - 0.031 14.0 1.2 7.1 6.3 0.4 2.6 2 1 0 2 2 2 0 Alpha/beta hydrolase family Esterase PF00756.15 KFX99219.1 - 0.039 13.3 0.1 0.063 12.6 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Serglycin PF04360.7 KFX99220.1 - 0.081 12.6 2.1 0.22 11.2 1.0 2.0 2 1 0 2 2 2 0 Serglycin DUF3336 PF11815.3 KFX99221.1 - 7.3e-37 126.0 0.1 2e-36 124.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KFX99221.1 - 2e-15 57.3 0.8 4.8e-15 56.0 0.1 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase HpcH_HpaI PF03328.9 KFX99222.1 - 1.2e-34 119.1 0.0 1.6e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Radical_SAM PF04055.16 KFX99222.1 - 0.06 13.5 0.0 0.53 10.4 0.0 2.2 2 1 0 2 2 2 0 Radical SAM superfamily Cellulase PF00150.13 KFX99224.1 - 6.8e-08 32.0 0.0 1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CPL PF08144.6 KFX99225.1 - 9.9e-20 70.8 0.2 1.6e-18 66.9 0.0 3.1 3 1 1 4 4 4 1 CPL (NUC119) domain TFIIF_alpha PF05793.7 KFX99225.1 - 0.11 10.8 34.8 0.009 14.4 15.7 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3206 PF11472.3 KFX99225.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) RWD PF05773.17 KFX99226.1 - 4e-23 81.4 0.7 1.1e-22 80.0 0.0 2.0 2 1 0 2 2 2 1 RWD domain Tfb2 PF03849.9 KFX99226.1 - 0.11 11.1 1.2 0.14 10.7 0.9 1.1 1 0 0 1 1 1 0 Transcription factor Tfb2 DUF3818 PF12825.2 KFX99226.1 - 0.22 10.1 3.6 0.29 9.7 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) DUF488 PF04343.8 KFX99226.1 - 0.27 11.6 3.0 0.51 10.7 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF488 DUF2175 PF09943.4 KFX99226.1 - 7.5 6.6 8.2 6.4 6.9 0.7 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) TPR_12 PF13424.1 KFX99227.1 - 1e-11 44.5 0.2 4.5e-06 26.5 0.0 3.3 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFX99227.1 - 1.7e-11 43.0 1.1 4.9e-05 22.9 0.0 5.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFX99227.1 - 3.2e-11 42.7 0.0 8.9e-06 25.2 0.0 3.2 3 0 0 3 3 3 2 TPR repeat TPR_16 PF13432.1 KFX99227.1 - 3.6e-11 43.4 2.4 0.00043 20.8 0.2 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFX99227.1 - 1.5e-10 40.7 5.2 0.059 14.0 0.0 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFX99227.1 - 2.3e-10 40.6 4.7 0.0011 19.2 0.1 3.9 3 1 1 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFX99227.1 - 6.7e-10 38.0 4.4 0.00025 20.6 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFX99227.1 - 2.6e-09 36.1 0.0 3.5e-05 23.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFX99227.1 - 6.4e-08 31.8 0.1 0.00026 20.4 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFX99227.1 - 0.00018 21.7 1.5 1.4 9.5 0.0 4.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFX99227.1 - 0.00062 19.7 0.0 22 5.5 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 KFX99227.1 - 0.00078 19.4 0.5 1 9.2 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 KFX99227.1 - 0.003 17.6 0.2 1.8 8.6 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFX99227.1 - 0.019 14.9 12.3 0.038 13.9 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFX99227.1 - 0.02 15.2 7.5 1.9 9.1 0.1 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat zf-His_Me_endon PF05551.6 KFX99243.1 - 3e-12 46.6 1.2 5.6e-12 45.7 0.8 1.4 1 0 0 1 1 1 1 Zinc-binding loop region of homing endonuclease 4HBT_3 PF13622.1 KFX99244.1 - 1.8e-48 165.5 0.0 2.2e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 KFX99244.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Thioesterase superfamily CUE PF02845.11 KFX99245.1 - 7.3e-11 41.3 0.3 1.7e-10 40.1 0.2 1.6 1 0 0 1 1 1 1 CUE domain NOA36 PF06524.7 KFX99245.1 - 1.4 8.1 2.7 2.1 7.5 1.9 1.1 1 0 0 1 1 1 0 NOA36 protein Ribosomal_S10 PF00338.17 KFX99246.1 - 5.7e-30 103.0 0.5 6.8e-30 102.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-CCCH PF00642.19 KFX99247.1 - 0.00018 21.0 1.3 0.00033 20.2 0.9 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KFX99247.1 - 0.58 10.2 4.4 1.3 9.1 3.1 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Tim17 PF02466.14 KFX99258.1 - 9.9e-27 93.5 4.0 1.3e-26 93.1 2.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2428 PF10350.4 KFX99259.1 - 1.9e-62 210.5 0.3 6.4e-62 208.8 0.0 2.0 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 KFX99259.1 - 0.0026 17.7 1.3 7.8 6.8 0.0 5.0 5 0 0 5 5 5 1 HEAT repeat TEX15 PF15326.1 KFX99259.1 - 0.0036 16.9 1.4 0.01 15.5 0.7 1.9 2 0 0 2 2 2 1 Testis expressed sequence 15 MAPEG PF01124.13 KFX99260.1 - 6e-22 77.6 1.4 7e-22 77.4 0.9 1.1 1 0 0 1 1 1 1 MAPEG family XPA_C PF05181.7 KFX99282.1 - 1.8e-28 97.8 3.6 1.8e-28 97.8 2.5 1.9 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.13 KFX99282.1 - 0.0023 17.5 1.5 0.0038 16.8 1.1 1.3 1 0 0 1 1 1 1 XPA protein N-terminal ArfGap PF01412.13 KFX99282.1 - 1.8 8.3 4.9 0.36 10.6 0.4 1.9 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf PQ-loop PF04193.9 KFX99288.1 - 1.3e-37 127.1 14.2 3.6e-21 74.4 0.0 3.3 3 1 1 4 4 4 2 PQ loop repeat Glyco_hydro_17 PF00332.13 KFX99289.1 - 8.3e-28 97.3 1.1 3.6e-24 85.3 0.6 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 PAM2 PF07145.10 KFX99290.1 - 5.7 6.6 25.9 0.27 10.8 0.7 5.5 6 0 0 6 6 6 0 Ataxin-2 C-terminal region Phosphodiest PF01663.17 KFX99291.1 - 4.2e-86 289.5 0.1 5.5e-86 289.1 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KFX99291.1 - 0.0021 17.3 0.2 0.089 11.9 0.1 2.5 1 1 0 1 1 1 1 Sulfatase PglZ PF08665.7 KFX99291.1 - 0.027 14.1 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 PglZ domain Dsh_C PF12316.3 KFX99291.1 - 2.5 8.1 10.7 0.19 11.8 3.3 2.1 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Med26 PF08711.6 KFX99292.1 - 1.8e-11 43.3 0.0 3.1e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Nup54 PF13874.1 KFX99293.1 - 4.2e-43 146.3 0.0 4.2e-43 146.3 0.0 2.8 3 1 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 KFX99293.1 - 1.7e-18 66.9 77.9 2.1e-10 40.8 28.4 2.6 1 1 1 2 2 2 2 Nucleoporin FG repeat region NADH_u_ox_C PF12853.2 KFX99294.1 - 5.7e-35 118.9 0.2 8.5e-35 118.3 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.4 KFX99294.1 - 1.3e-33 115.0 0.3 2e-33 114.4 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit dCMP_cyt_deam_1 PF00383.17 KFX99295.1 - 1.5e-22 79.1 0.0 2.4e-22 78.4 0.0 1.3 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KFX99295.1 - 4e-06 26.7 0.0 6.1e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Bd3614-like deaminase adh_short PF00106.20 KFX99297.1 - 3.2e-26 92.2 3.0 4.6e-26 91.7 2.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX99297.1 - 2.8e-17 63.2 0.1 3.7e-17 62.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX99297.1 - 9.8e-11 41.6 2.5 1.6e-10 40.9 1.7 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFX99297.1 - 7.7e-07 29.2 0.6 1.6e-06 28.2 0.4 1.5 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KFX99297.1 - 0.0016 17.4 0.3 0.0037 16.2 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 KFX99297.1 - 0.0026 17.2 0.1 0.22 10.9 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 KFX99297.1 - 0.0042 17.0 0.1 0.11 12.5 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain DUF1776 PF08643.5 KFX99297.1 - 0.0073 15.4 0.0 0.0091 15.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) PP2C_2 PF13672.1 KFX99297.1 - 0.0076 15.6 0.2 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Eno-Rase_NADH_b PF12242.3 KFX99297.1 - 0.074 12.8 0.3 0.26 11.1 0.1 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_4 PF07993.7 KFX99297.1 - 0.089 11.6 0.1 2.5 6.9 0.0 2.3 1 1 1 2 2 2 0 Male sterility protein NmrA PF05368.8 KFX99297.1 - 0.099 11.8 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family CBFD_NFYB_HMF PF00808.18 KFX99298.1 - 4.1e-17 61.9 0.6 7.2e-17 61.2 0.2 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFX99298.1 - 1.3e-05 25.2 0.1 8.9e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 ADH_zinc_N PF00107.21 KFX99299.1 - 1.3e-13 50.6 0.1 2.7e-13 49.5 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX99299.1 - 0.031 14.0 0.0 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain MORN PF02493.15 KFX99299.1 - 3.7 7.4 6.1 8.9 6.2 0.1 3.0 3 0 0 3 3 3 0 MORN repeat Glycoprotein_B PF00606.13 KFX99313.1 - 0.36 8.7 1.5 0.49 8.3 1.0 1.2 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B CNH PF00780.17 KFX99314.1 - 1.5e-82 277.1 0.0 2.3e-82 276.5 0.0 1.3 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 KFX99314.1 - 9.6e-45 151.8 0.3 2.9e-44 150.3 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain RhoGEF PF00621.15 KFX99314.1 - 2.1e-36 125.5 0.0 3.4e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 KFX99314.1 - 1.6e-13 50.1 0.0 5.8e-13 48.3 0.0 1.9 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ATP-synt_C PF00137.16 KFX99315.1 - 2.1e-26 91.5 31.5 3.4e-15 55.6 6.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C PI3Ka PF00613.15 KFX99316.1 - 3.1e-58 195.9 0.3 5.1e-58 195.2 0.2 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 KFX99316.1 - 9.1e-42 143.1 0.0 4.1e-41 141.0 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 KFX99316.1 - 1.7e-30 105.6 0.0 2.9e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.5 KFX99317.1 - 1.3e-33 114.8 0.0 2.6e-33 113.8 0.0 1.6 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 KFX99317.1 - 1.5e-10 40.7 0.8 4.3e-10 39.2 0.5 1.9 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE Sugar_tr PF00083.19 KFX99318.1 - 2.8e-120 401.9 25.1 3.2e-120 401.7 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX99318.1 - 1.6e-20 73.1 28.1 1.6e-20 73.1 19.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF261 PF03196.8 KFX99318.1 - 0.67 9.9 3.2 0.44 10.5 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF261 DUF3154 PF11351.3 KFX99318.1 - 2.1 8.1 5.4 3.1 7.5 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3154) DUF447 PF04289.7 KFX99319.1 - 0.094 12.2 0.2 0.23 11.0 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF447) DUF1749 PF08538.5 KFX99322.1 - 2e-98 329.0 0.0 2.2e-98 328.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KFX99322.1 - 1.9e-05 24.7 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX99322.1 - 0.00026 20.7 0.0 0.00067 19.4 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF2305 PF10230.4 KFX99322.1 - 0.011 15.1 0.1 0.27 10.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 KFX99322.1 - 0.023 14.2 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase DUF900 PF05990.7 KFX99322.1 - 0.095 12.0 0.1 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) MRP-L28 PF09812.4 KFX99323.1 - 6.4e-09 35.8 0.2 9e-09 35.3 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Bac_small_YrzI PF09501.5 KFX99323.1 - 0.063 13.1 0.4 0.11 12.4 0.3 1.3 1 0 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) Ras PF00071.17 KFX99324.1 - 2.5e-48 163.5 0.0 4.5e-48 162.6 0.0 1.4 2 0 0 2 2 2 1 Ras family Miro PF08477.8 KFX99324.1 - 3e-15 56.7 0.0 5e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFX99324.1 - 1.7e-06 27.3 0.0 2.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFX99324.1 - 0.011 14.9 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KFX99324.1 - 0.029 13.8 0.0 2.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 KFX99324.1 - 0.049 12.8 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NST1 PF13945.1 KFX99325.1 - 3.2e-59 200.1 2.0 3.2e-59 200.1 1.4 4.6 3 1 1 4 4 4 1 Salt tolerance down-regulator Baculo_PEP_C PF04513.7 KFX99328.1 - 0.00067 19.4 12.0 1.3 8.7 0.1 4.3 2 2 2 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2523 PF10734.4 KFX99328.1 - 0.79 9.9 0.0 0.79 9.9 0.0 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2523) DUF1741 PF08427.5 KFX99329.1 - 8.9e-45 152.9 0.0 1.1e-44 152.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Kelch_5 PF13854.1 KFX99331.1 - 1.4e-07 31.2 0.7 3.6e-06 26.7 0.0 3.3 3 0 0 3 3 3 1 Kelch motif SKG6 PF08693.5 KFX99331.1 - 0.0041 16.3 1.3 0.0084 15.4 0.9 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_3 PF13415.1 KFX99331.1 - 0.03 14.4 0.1 4.4 7.5 0.0 3.6 2 0 0 2 2 2 0 Galactose oxidase, central domain DUF456 PF04306.8 KFX99331.1 - 0.66 10.0 4.5 1.2 9.1 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) SPOC PF07744.8 KFX99332.1 - 1.2e-18 67.6 0.0 4.4e-18 65.8 0.0 2.0 2 0 0 2 2 2 1 SPOC domain TFIIS_M PF07500.9 KFX99332.1 - 2.1e-15 56.7 2.9 5.2e-15 55.5 2.0 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 KFX99332.1 - 1.5e-09 37.4 9.8 2.8e-09 36.5 6.8 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KFX99332.1 - 0.82 9.0 5.0 1.6 8.0 3.5 1.5 1 0 0 1 1 1 0 PHD-finger zf-C2H2_jaz PF12171.3 KFX99333.1 - 2e-06 27.7 0.0 3.4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFX99333.1 - 0.00021 21.3 0.1 0.00035 20.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KFX99333.1 - 0.055 13.5 0.1 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Sds3 PF08598.6 KFX99333.1 - 0.068 12.6 11.7 0.029 13.8 2.7 2.3 2 0 0 2 2 2 0 Sds3-like Fzo_mitofusin PF04799.8 KFX99333.1 - 0.61 9.4 2.0 0.97 8.7 1.4 1.2 1 0 0 1 1 1 0 fzo-like conserved region Cwf_Cwc_15 PF04889.7 KFX99333.1 - 1.9 8.1 26.0 4.6 6.8 1.4 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CAF-1_p150 PF11600.3 KFX99333.1 - 7.7 5.8 27.8 3.2 7.0 10.5 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal FF PF01846.14 KFX99334.1 - 2.2e-10 40.2 2.4 4.8e-08 32.8 0.0 3.1 3 0 0 3 3 3 1 FF domain WW PF00397.21 KFX99334.1 - 7e-09 35.4 4.9 1.7e-08 34.1 3.4 1.7 1 0 0 1 1 1 1 WW domain DDHD PF02862.12 KFX99334.1 - 1.1 9.0 5.7 1.9 8.2 0.5 2.3 2 1 0 2 2 2 0 DDHD domain Di19_C PF14571.1 KFX99334.1 - 2.3 8.5 11.6 0.19 12.0 0.2 3.3 3 0 0 3 3 3 0 Stress-induced protein Di19, C-terminal Proteasome PF00227.21 KFX99335.1 - 1.3e-59 200.6 0.2 1.7e-59 200.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFX99335.1 - 2.8e-14 52.0 0.2 7.1e-14 50.8 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.9 KFX99335.1 - 0.057 12.7 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit PAP2 PF01569.16 KFX99336.1 - 2.3e-20 72.5 1.4 2.3e-20 72.5 1.0 1.9 2 1 0 2 2 2 1 PAP2 superfamily DUF350 PF03994.9 KFX99336.1 - 0.13 11.9 0.3 0.13 11.9 0.2 2.5 4 0 0 4 4 4 0 Domain of Unknown Function (DUF350) RseC_MucC PF04246.7 KFX99336.1 - 1.4 8.4 5.7 0.28 10.7 0.2 2.4 3 1 1 4 4 4 0 Positive regulator of sigma(E), RseC/MucC Med7 PF05983.6 KFX99337.1 - 2.2e-58 196.6 0.0 2.7e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 MED7 protein GYD PF08734.6 KFX99337.1 - 0.12 12.1 0.0 0.37 10.5 0.0 1.7 2 0 0 2 2 2 0 GYD domain DUF747 PF05346.6 KFX99338.1 - 9.7e-129 429.1 4.2 1.4e-128 428.5 2.9 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family DNA_methylase PF00145.12 KFX99338.1 - 1e-46 159.6 0.0 5.2e-46 157.3 0.0 2.3 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 KFX99338.1 - 7e-17 61.2 0.0 1.7e-12 47.1 0.0 3.3 3 0 0 3 3 3 2 BAH domain Beta-lactamase PF00144.19 KFX99347.1 - 3.1e-21 75.7 0.0 8.6e-21 74.2 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Zn_clus PF00172.13 KFX99348.1 - 8.9e-06 25.5 9.7 8.9e-06 25.5 6.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFX99348.1 - 0.00026 19.7 0.1 0.0013 17.4 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain GST_C_2 PF13410.1 KFX99348.1 - 0.062 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FAD_binding_3 PF01494.14 KFX99349.1 - 1.1e-24 87.1 0.0 1.4e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFX99349.1 - 2.2e-10 40.0 0.0 0.00037 19.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KFX99349.1 - 2.5e-06 26.6 0.1 2.3e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KFX99349.1 - 5.3e-05 23.3 0.0 0.00011 22.2 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFX99349.1 - 0.00012 22.0 0.1 0.00033 20.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KFX99349.1 - 0.00017 20.2 0.0 0.0017 16.8 0.0 2.0 1 1 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.19 KFX99349.1 - 0.00017 20.8 0.2 0.033 13.2 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 KFX99349.1 - 0.0012 19.2 0.3 0.023 15.0 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KFX99349.1 - 0.017 15.0 0.1 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.9 KFX99349.1 - 0.092 11.3 0.1 0.26 9.8 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Thi4 PF01946.12 KFX99349.1 - 0.16 11.0 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family MFS_1 PF07690.11 KFX99350.1 - 1.1e-32 113.1 32.1 1.4e-32 112.7 22.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1360 PF07098.6 KFX99350.1 - 0.037 13.7 1.0 0.12 12.1 0.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) Fungal_trans PF04082.13 KFX99351.1 - 3.9e-20 71.8 0.8 9.2e-20 70.6 0.5 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KFX99351.1 - 2.7e-07 30.5 6.9 0.0081 16.4 1.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.13 KFX99351.1 - 6.8e-06 25.8 6.3 6.8e-06 25.8 4.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 KFX99351.1 - 4.3e-05 23.5 7.2 0.043 14.1 0.1 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFX99351.1 - 0.00051 20.1 0.3 0.00051 20.1 0.2 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-Di19 PF05605.7 KFX99351.1 - 0.14 12.3 1.4 0.36 10.9 1.0 1.8 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding DUF3920 PF13058.1 KFX99351.1 - 0.24 11.2 0.0 0.45 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3920) zf-C2H2_jaz PF12171.3 KFX99351.1 - 0.29 11.3 1.7 6.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Aldo_ket_red PF00248.16 KFX99352.1 - 1.5e-53 181.5 0.0 1.7e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NUDIX PF00293.23 KFX99353.1 - 4.1e-08 32.9 0.2 2e-07 30.7 0.0 2.1 3 0 0 3 3 3 1 NUDIX domain MFS_1 PF07690.11 KFX99354.1 - 1.3e-28 99.8 15.5 1.6e-28 99.4 7.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF2970 PF11174.3 KFX99354.1 - 0.039 13.5 1.4 0.091 12.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) DUF1228 PF06779.9 KFX99354.1 - 0.14 12.1 7.6 2.5 8.1 0.3 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) FAD_binding_4 PF01565.18 KFX99356.1 - 1.2e-21 76.6 4.6 2.6e-21 75.5 3.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFX99356.1 - 0.00082 19.2 0.4 0.0016 18.2 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like GTP_EFTU_D3 PF03143.12 KFX99357.1 - 1.1e-14 54.3 0.0 1.8e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFX99357.1 - 2.2e-05 24.4 0.1 0.00024 21.1 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Cro PF09048.5 KFX99358.1 - 0.094 12.3 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Cro Aldo_ket_red PF00248.16 KFX99359.1 - 7.5e-59 198.8 0.0 8.6e-59 198.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2380 PF09533.5 KFX99359.1 - 0.064 12.6 0.1 5.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Predicted lipoprotein of unknown function (DUF2380) Dna2 PF08696.6 KFX99360.1 - 2.4e-70 236.0 0.2 4.5e-70 235.1 0.2 1.5 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 KFX99360.1 - 1.5e-50 171.3 0.0 2.6e-50 170.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFX99360.1 - 3.9e-39 134.6 0.5 1.1e-19 71.0 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 KFX99360.1 - 3e-12 46.5 0.0 8.8e-12 45.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFX99360.1 - 1.2e-11 44.2 0.2 3.7e-11 42.6 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain Cas_Cas4 PF01930.12 KFX99360.1 - 3.4e-10 40.0 0.1 5.1e-09 36.2 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.2 KFX99360.1 - 3.1e-08 33.3 0.0 6.1e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 KFX99360.1 - 1.3e-07 31.4 0.6 0.27 10.6 0.0 4.1 4 1 0 4 4 4 2 Viral (Superfamily 1) RNA helicase DUF911 PF06023.7 KFX99360.1 - 0.00012 21.4 0.1 0.00036 19.8 0.0 1.7 1 1 0 1 1 1 1 Archaeal protein of unknown function (DUF911) Helicase_RecD PF05127.9 KFX99360.1 - 0.00024 20.8 0.0 0.00067 19.3 0.0 1.8 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.16 KFX99360.1 - 0.0003 20.1 0.1 0.00068 19.0 0.0 1.6 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 KFX99360.1 - 0.00032 19.7 0.0 0.00076 18.5 0.0 1.6 1 0 0 1 1 1 1 PIF1-like helicase SRP54 PF00448.17 KFX99360.1 - 0.00048 19.6 0.1 0.00086 18.7 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 KFX99360.1 - 0.001 19.1 0.0 0.0026 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 KFX99360.1 - 0.0017 18.0 0.1 0.0041 16.8 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 KFX99360.1 - 0.0027 17.1 0.0 0.0073 15.7 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.1 KFX99360.1 - 0.0036 16.7 0.0 0.032 13.6 0.0 2.5 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.4 KFX99360.1 - 0.0067 15.4 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 KFX99360.1 - 0.018 15.3 0.0 2 8.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.1 KFX99360.1 - 0.021 14.9 0.0 0.079 13.1 0.0 2.0 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain T2SE PF00437.15 KFX99360.1 - 0.029 13.2 0.1 0.057 12.3 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ArgK PF03308.11 KFX99360.1 - 0.044 12.5 0.1 0.12 11.1 0.0 1.6 2 0 0 2 2 2 0 ArgK protein DUF87 PF01935.12 KFX99360.1 - 0.047 13.4 2.0 0.094 12.5 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_22 PF13401.1 KFX99360.1 - 0.066 13.3 0.1 0.29 11.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KFX99360.1 - 0.07 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 KFX99360.1 - 0.071 12.9 0.1 0.64 9.8 0.0 2.6 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.10 KFX99360.1 - 0.082 12.6 0.2 0.25 11.0 0.1 1.8 1 0 0 1 1 1 0 NTPase Miro PF08477.8 KFX99360.1 - 0.14 12.6 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein DUF543 PF04418.7 KFX99366.1 - 2.3e-25 88.3 0.0 5.4e-25 87.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF543) zf-CCHC PF00098.18 KFX99366.1 - 5.9e-06 25.9 24.6 0.067 13.1 2.7 4.7 4 0 0 4 4 4 3 Zinc knuckle ORMDL PF04061.9 KFX99367.1 - 1.1e-07 31.4 0.0 1.6e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 ORMDL family ORMDL PF04061.9 KFX99368.1 - 2.6e-40 137.1 0.4 2.9e-40 136.9 0.3 1.0 1 0 0 1 1 1 1 ORMDL family DUF3729 PF12526.3 KFX99372.1 - 2.7 9.3 8.7 3.4 9.0 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) HsbA PF12296.3 KFX99374.1 - 4.8e-26 91.0 9.1 7.6e-26 90.4 6.3 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Peptidase_M75 PF09375.5 KFX99374.1 - 0.0013 18.0 2.8 0.012 14.9 1.9 1.9 1 1 0 1 1 1 1 Imelysin Baculo_PEP_C PF04513.7 KFX99374.1 - 0.0025 17.6 5.4 0.076 12.8 1.9 2.1 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 KFX99374.1 - 2.7 8.3 5.6 8.6 6.6 1.9 2.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein AAT PF03417.11 KFX99375.1 - 2.4e-19 69.6 0.0 2.5e-17 63.0 0.0 2.9 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 KFX99375.1 - 1.7e-05 25.0 0.0 2.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase TRAPP PF04051.11 KFX99376.1 - 1.8e-37 128.1 0.1 2.1e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component WD40 PF00400.27 KFX99377.1 - 1.5e-56 186.3 6.2 3.3e-10 39.4 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KFX99377.1 - 0.00078 18.2 0.4 0.094 11.4 0.1 2.2 1 1 0 2 2 2 2 Nup133 N terminal like BBS2_Mid PF14783.1 KFX99377.1 - 0.11 12.2 0.0 0.71 9.6 0.0 2.3 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, middle region FHA PF00498.21 KFX99387.1 - 0.0006 19.8 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 FHA domain MFS_1 PF07690.11 KFX99388.1 - 3.5e-34 118.0 36.6 3.5e-34 118.0 25.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2512 PF10710.4 KFX99388.1 - 0.083 12.3 1.9 2.5 7.5 0.0 3.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2512) DUF3633 PF12315.3 KFX99388.1 - 0.17 11.1 0.0 0.34 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) Sugar_tr PF00083.19 KFX99388.1 - 0.26 9.8 39.8 0.017 13.7 13.8 2.3 1 1 1 3 3 3 0 Sugar (and other) transporter Sugar_tr PF00083.19 KFX99389.1 - 3.2e-69 233.6 27.5 4.3e-69 233.2 19.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX99389.1 - 4.1e-15 55.3 27.6 4.1e-15 55.3 19.2 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Glyco_hydro_32N PF00251.15 KFX99390.1 - 1.8e-50 172.0 0.0 4.5e-50 170.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 KFX99390.1 - 2.2e-11 43.9 0.1 4.5e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.1 KFX99390.1 - 0.0035 16.6 0.1 0.0073 15.6 0.0 1.4 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 KFX99390.1 - 0.067 13.0 1.7 0.67 10.0 0.2 3.3 2 0 0 2 2 2 0 BNR/Asp-box repeat Fungal_trans PF04082.13 KFX99391.1 - 4.5e-07 28.9 0.9 4.5e-07 28.9 0.6 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3656 PF12392.3 KFX99391.1 - 0.076 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Collagenase DUF2961 PF11175.3 KFX99392.1 - 9.1e-86 287.0 4.3 1.2e-85 286.6 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2961) Pkinase PF00069.20 KFX99401.1 - 1.3e-52 178.5 0.0 3e-52 177.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX99401.1 - 2e-23 82.7 0.1 5.5e-23 81.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KFX99401.1 - 0.00013 21.7 3.3 0.00047 19.9 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFX99401.1 - 0.0038 16.6 0.2 0.014 14.7 0.2 1.7 1 1 0 1 1 1 1 RIO1 family DUF4430 PF14478.1 KFX99401.1 - 0.15 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) SNF2_N PF00176.18 KFX99402.1 - 8.5e-69 231.6 0.0 1.3e-68 231.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFX99402.1 - 2.5e-15 56.0 0.0 8.7e-15 54.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KFX99402.1 - 1.2e-05 24.3 0.0 2.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KFX99402.1 - 0.00011 22.1 0.2 0.00055 19.8 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFX99402.1 - 0.017 14.6 0.0 0.47 9.9 0.0 2.6 2 1 0 2 2 2 0 DEAD/DEAH box helicase LON PF02190.11 KFX99403.1 - 2.1e-24 86.3 0.0 3.1e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 KFX99403.1 - 1.4e-08 34.5 10.4 4e-08 33.1 7.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX99403.1 - 1.5e-08 34.1 9.9 3.2e-08 33.0 6.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFX99403.1 - 1.5e-08 34.3 10.3 1.5e-08 34.3 7.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFX99403.1 - 3.2e-08 33.0 5.8 7.9e-08 31.8 4.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX99403.1 - 1e-07 31.5 8.8 1e-07 31.5 6.1 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFX99403.1 - 4e-07 29.6 3.1 1.1e-06 28.2 0.8 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFX99403.1 - 8.4e-07 28.7 7.0 5.3e-06 26.2 5.2 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 KFX99403.1 - 0.0016 17.8 6.6 0.0044 16.4 4.6 1.8 1 0 0 1 1 1 1 P-11 zinc finger U-box PF04564.10 KFX99403.1 - 0.0021 17.9 0.0 0.0042 17.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-RING_4 PF14570.1 KFX99403.1 - 0.0042 16.6 7.2 0.015 14.8 5.0 2.0 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 KFX99403.1 - 0.13 11.8 4.4 0.27 10.8 3.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 KFX99403.1 - 0.15 12.1 10.6 0.033 14.2 4.6 2.0 2 1 0 2 2 2 0 RING-H2 zinc finger zf-Apc11 PF12861.2 KFX99403.1 - 0.21 11.4 1.9 0.54 10.1 1.3 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger MTHFR_C PF12225.3 KFX99403.1 - 0.49 9.9 4.0 15 5.1 0.7 2.3 2 0 0 2 2 2 0 Methylene-tetrahydrofolate reductase C terminal zf-Nse PF11789.3 KFX99403.1 - 1.2 8.7 9.8 0.25 10.8 3.3 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RRM_1 PF00076.17 KFX99404.1 - 0.0013 18.3 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PPR_2 PF13041.1 KFX99406.1 - 2.6e-25 88.1 2.2 4.4e-17 61.7 0.0 4.5 4 1 1 5 5 5 2 PPR repeat family PPR PF01535.15 KFX99406.1 - 7.5e-09 34.9 1.8 0.00049 19.8 0.0 5.4 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.1 KFX99406.1 - 6.3e-08 32.2 1.2 0.86 10.0 0.0 6.5 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 KFX99406.1 - 1.3e-05 24.5 1.2 0.016 14.6 0.0 4.5 5 0 0 5 5 5 1 PPR repeat YodL PF14191.1 KFX99406.1 - 0.027 14.9 0.3 3 8.3 0.0 3.1 3 0 0 3 3 3 0 YodL-like DNA_pol_B PF00136.16 KFX99407.1 - 6.2e-109 364.8 3.4 1e-108 364.1 2.3 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 KFX99407.1 - 1.4e-63 213.7 0.7 2.3e-63 212.9 0.5 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 KFX99407.1 - 7.6e-40 136.7 0.0 2e-39 135.3 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 KFX99407.1 - 5.5e-23 80.5 10.4 5.5e-23 80.5 7.2 2.6 3 0 0 3 3 3 1 DNA polymerase alpha subunit p180 N terminal FAD_binding_3 PF01494.14 KFX99411.1 - 1.5e-32 113.0 0.0 2e-32 112.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 KFX99411.1 - 0.18 10.5 0.0 0.27 10.0 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase SAGA-Tad1 PF12767.2 KFX99412.1 - 2.9e-55 187.6 0.0 3.7e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Spc97_Spc98 PF04130.8 KFX99413.1 - 5e-120 401.3 0.0 6.2e-120 401.0 0.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF3921 PF13060.1 KFX99413.1 - 0.0049 16.7 0.1 0.014 15.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3921) WD40 PF00400.27 KFX99414.1 - 1.1e-50 167.7 22.4 2e-08 33.7 0.2 10.6 10 0 0 10 10 10 10 WD domain, G-beta repeat eIF2A PF08662.6 KFX99414.1 - 1.7e-05 24.6 2.7 0.74 9.4 0.0 4.5 4 2 1 5 5 5 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 KFX99414.1 - 0.0014 17.7 2.3 2.3 7.2 0.0 4.4 4 1 1 5 5 5 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 KFX99414.1 - 0.026 14.1 0.6 5.7 6.7 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.2 KFX99414.1 - 0.51 10.0 4.0 0.9 9.2 0.6 2.7 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term PhyH PF05721.8 KFX99415.1 - 1.9e-08 34.5 0.0 2.2e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3328 PF11807.3 KFX99421.1 - 0.092 12.4 2.7 0.75 9.4 0.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3328) DUF3671 PF12420.3 KFX99421.1 - 0.11 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function MFS_1 PF07690.11 KFX99422.1 - 1.1e-38 132.8 53.1 3.9e-37 127.7 22.7 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFX99422.1 - 3.6e-15 55.5 8.6 3.6e-15 55.5 5.9 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KFX99422.1 - 3.3e-05 22.3 19.1 4.5e-05 21.8 13.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GATase PF00117.23 KFX99423.1 - 6.9e-13 48.4 0.0 8.5e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KFX99423.1 - 0.00059 19.3 1.5 0.048 13.0 1.1 2.8 1 1 0 1 1 1 1 Peptidase C26 Senescence PF06911.7 KFX99424.1 - 6.7e-45 152.9 6.9 1.1e-44 152.2 4.8 1.4 1 0 0 1 1 1 1 Senescence-associated protein Rho_GDI PF02115.12 KFX99425.1 - 5.7e-59 198.8 0.3 6.3e-59 198.7 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.23 KFX99426.1 - 2.6e-43 147.7 0.6 3.2e-43 147.4 0.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-CCHC PF00098.18 KFX99427.1 - 0.00038 20.2 1.7 0.00074 19.3 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle Adaptin_N PF01602.15 KFX99428.1 - 1.2e-105 353.8 0.0 1.4e-105 353.6 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KFX99428.1 - 4.6e-13 49.2 1.1 7.8e-05 22.8 0.0 5.1 3 2 2 5 5 5 5 HEAT repeats HEAT PF02985.17 KFX99428.1 - 2.2e-10 39.7 0.0 0.058 13.5 0.0 5.4 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 KFX99428.1 - 6e-05 23.3 2.1 0.013 15.9 0.0 4.6 4 0 0 4 4 4 1 HEAT-like repeat Cohesin_HEAT PF12765.2 KFX99428.1 - 0.0041 17.0 0.0 1.2 9.2 0.0 2.9 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion VHS PF00790.14 KFX99428.1 - 0.048 13.2 1.1 52 3.4 0.0 3.9 4 0 0 4 4 4 0 VHS domain UCR_TM PF02921.9 KFX99430.1 - 1.6e-20 73.1 1.7 1.6e-20 73.1 1.2 1.8 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 KFX99430.1 - 1e-18 66.6 0.0 1.6e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pectinesterase PF01095.14 KFX99431.1 - 1.7e-31 108.9 0.3 7e-24 83.9 0.1 2.1 2 0 0 2 2 2 2 Pectinesterase Alpha-amylase PF00128.19 KFX99432.1 - 2.5e-97 326.0 1.0 3.8e-97 325.4 0.1 1.6 2 0 0 2 2 2 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KFX99432.1 - 0.019 13.8 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Glyco_hydro_42C PF08533.5 KFX99432.1 - 0.062 12.8 0.1 2.3 7.8 0.0 2.7 3 0 0 3 3 3 0 Beta-galactosidase C-terminal domain Sugar_tr PF00083.19 KFX99433.1 - 3.7e-86 289.4 25.3 4.3e-86 289.2 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX99433.1 - 1.2e-16 60.4 34.7 1.9e-16 59.7 20.2 2.5 1 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX99433.1 - 0.00019 20.0 31.4 0.001 17.5 4.3 3.5 2 2 2 4 4 4 3 MFS/sugar transport protein Fungal_trans PF04082.13 KFX99434.1 - 8.2e-15 54.3 2.4 1.3e-14 53.6 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX99434.1 - 2.3e-06 27.4 11.5 5.2e-06 26.2 7.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydrolase_6 PF13344.1 KFX99435.1 - 1.5e-21 76.1 0.0 3.5e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFX99435.1 - 1.8e-17 62.7 0.0 5.3e-17 61.2 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 KFX99435.1 - 0.00027 21.1 0.0 0.3 11.3 0.0 3.3 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFX99435.1 - 0.019 15.3 0.0 0.24 11.7 0.0 2.5 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase DUF605 PF04652.11 KFX99453.1 - 4.5 6.5 18.1 5 6.4 12.5 1.0 1 0 0 1 1 1 0 Vta1 like PLA2_B PF01735.13 KFX99454.1 - 2.4e-195 649.3 0.6 2.9e-195 649.1 0.4 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Cupin_2 PF07883.6 KFX99455.1 - 7.8e-05 22.1 0.1 0.0016 17.9 0.0 2.3 1 1 0 1 1 1 1 Cupin domain AT_hook PF02178.14 KFX99456.1 - 0.9 9.4 14.4 1.1 9.1 0.2 4.3 3 0 0 3 3 3 0 AT hook motif PBP1_TM PF14812.1 KFX99456.1 - 0.97 9.7 6.9 9.6 6.5 1.9 3.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Methyltransf_2 PF00891.13 KFX99457.1 - 3.5e-24 85.3 0.0 9.6e-24 83.9 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase Rrf2 PF02082.15 KFX99457.1 - 0.04 14.0 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Transcriptional regulator Methyltransf_23 PF13489.1 KFX99457.1 - 0.058 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF2325 PF10087.4 KFX99457.1 - 0.095 12.5 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) Dynactin_p22 PF07426.6 KFX99458.1 - 0.095 11.9 1.9 0.2 10.9 1.3 1.4 1 0 0 1 1 1 0 Dynactin subunit p22 WW PF00397.21 KFX99458.1 - 0.24 11.3 5.9 0.61 10.0 4.1 1.8 1 0 0 1 1 1 0 WW domain LMBR1 PF04791.11 KFX99458.1 - 0.29 9.6 0.1 0.47 8.9 0.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein IncA PF04156.9 KFX99458.1 - 1.2 8.7 9.0 3 7.3 6.2 1.6 1 0 0 1 1 1 0 IncA protein UbiA PF01040.13 KFX99459.1 - 1e-34 119.9 24.1 1.5e-34 119.3 16.7 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family Myb_DNA-bind_6 PF13921.1 KFX99460.1 - 6.8e-07 29.3 0.3 3.5e-06 27.0 0.1 2.2 1 1 1 2 2 2 1 Myb-like DNA-binding domain Minor_capsid_2 PF11114.3 KFX99460.1 - 0.25 11.2 5.0 0.97 9.3 0.1 2.3 2 0 0 2 2 2 0 Minor capsid protein TLD PF07534.11 KFX99461.1 - 2.2e-23 82.7 0.0 1.4e-22 80.1 0.0 2.0 1 1 0 1 1 1 1 TLD MUG2_C PF08593.5 KFX99461.1 - 0.16 12.2 15.2 1.2 9.4 10.5 2.4 1 1 0 1 1 1 0 Meiotically up-regulated glycoproteins C-terminal AAA_22 PF13401.1 KFX99462.1 - 1.7e-05 24.9 0.0 6.6e-05 23.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KFX99462.1 - 1.9e-05 24.3 0.0 4.9e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_2 PF07719.12 KFX99462.1 - 2.8e-05 23.6 2.6 0.019 14.8 0.2 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFX99462.1 - 2.8e-05 23.6 0.6 0.00017 21.1 0.3 2.5 3 0 0 3 3 3 1 TPR repeat TPR_8 PF13181.1 KFX99462.1 - 0.00077 19.0 0.5 1.3 8.9 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFX99462.1 - 0.00092 19.8 3.9 0.017 15.7 0.3 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFX99462.1 - 0.013 15.7 2.3 0.25 11.7 0.5 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat AAA_16 PF13191.1 KFX99462.1 - 0.075 13.0 0.1 0.49 10.3 0.0 2.4 1 1 0 1 1 1 0 AAA ATPase domain TPR_1 PF00515.23 KFX99462.1 - 0.13 11.8 1.4 11 5.8 0.4 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ORF6C PF10552.4 KFX99462.1 - 0.22 11.2 4.0 1 9.0 0.3 2.9 3 0 0 3 3 3 0 ORF6C domain TPR_12 PF13424.1 KFX99462.1 - 0.26 11.2 3.1 0.65 9.9 0.4 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat ZZ PF00569.12 KFX99462.1 - 0.55 9.8 2.3 1.4 8.5 1.6 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type SKG6 PF08693.5 KFX99463.1 - 0.0024 17.1 0.0 0.0024 17.1 0.0 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF3767 PF12597.3 KFX99463.1 - 0.24 11.0 2.2 9.3 5.9 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3767) OB_NTP_bind PF07717.11 KFX99481.1 - 7.8e-28 96.5 0.0 4.3e-27 94.1 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 KFX99481.1 - 4.1e-27 94.1 0.2 9.6e-27 92.9 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KFX99481.1 - 2.4e-12 46.5 0.0 5.6e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 KFX99481.1 - 7.6e-10 38.7 0.8 1.6e-09 37.6 0.5 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 KFX99481.1 - 2.2e-07 30.5 0.1 4.4e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KFX99481.1 - 8.6e-06 25.9 0.0 2.2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KFX99481.1 - 0.00028 20.5 0.1 0.0034 17.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 KFX99481.1 - 0.0003 19.7 0.1 0.00093 18.1 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_19 PF13245.1 KFX99481.1 - 0.0026 17.4 0.6 0.0083 15.8 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain Rib_5-P_isom_A PF06026.9 KFX99481.1 - 0.019 14.2 0.1 0.038 13.2 0.1 1.4 1 0 0 1 1 1 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) AAA_14 PF13173.1 KFX99481.1 - 0.036 13.9 0.4 0.3 10.9 0.3 2.2 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 KFX99481.1 - 0.094 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Cellulase PF00150.13 KFX99482.1 - 7.3e-17 61.4 4.9 9.8e-17 61.0 3.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.1 KFX99482.1 - 1.9e-07 30.7 0.8 1.9e-07 30.7 0.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4038) Glyco_hydro_2_C PF02836.12 KFX99482.1 - 2.2e-06 26.7 0.1 7.4e-06 25.0 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase-like PF12876.2 KFX99482.1 - 0.0017 18.7 0.0 0.0048 17.3 0.0 1.8 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 KFX99482.1 - 0.0048 16.0 1.0 0.0061 15.7 0.2 1.5 2 0 0 2 2 2 1 Beta-galactosidase Glyco_hydro_10 PF00331.15 KFX99482.1 - 0.023 13.7 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Sec1 PF00995.18 KFX99483.1 - 3e-144 481.7 0.0 3.4e-144 481.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Profilin PF00235.14 KFX99484.1 - 1.4e-39 134.9 0.8 1.7e-39 134.6 0.6 1.0 1 0 0 1 1 1 1 Profilin AAA PF00004.24 KFX99485.1 - 1.2e-52 177.5 0.0 3.9e-37 127.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFX99485.1 - 1.6e-07 31.5 5.2 0.0008 19.4 2.2 3.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 KFX99485.1 - 9.3e-06 25.4 0.1 0.11 12.1 0.0 3.3 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFX99485.1 - 9.6e-05 22.5 2.2 0.085 12.9 0.1 3.8 3 2 1 4 4 4 1 AAA domain AAA_28 PF13521.1 KFX99485.1 - 0.00023 21.1 0.0 0.014 15.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KFX99485.1 - 0.00059 19.7 0.0 0.017 15.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFX99485.1 - 0.00088 18.9 3.9 0.59 9.9 0.1 3.5 3 0 0 3 3 2 2 Part of AAA domain RuvB_N PF05496.7 KFX99485.1 - 0.0048 15.9 0.0 0.068 12.2 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KFX99485.1 - 0.005 16.0 0.9 0.66 9.0 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 KFX99485.1 - 0.005 17.6 0.1 0.36 11.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KFX99485.1 - 0.014 15.2 0.0 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KFX99485.1 - 0.03 13.9 1.4 0.14 11.7 0.1 2.6 3 0 0 3 3 3 0 NACHT domain Zeta_toxin PF06414.7 KFX99485.1 - 0.041 12.9 0.2 0.56 9.2 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin AAA_2 PF07724.9 KFX99485.1 - 0.11 12.4 0.0 0.75 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 KFX99485.1 - 0.26 11.4 0.0 33 4.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.10 KFX99485.1 - 0.29 9.7 0.0 0.5 8.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein IstB_IS21 PF01695.12 KFX99485.1 - 0.35 10.2 2.3 3.3 7.0 0.1 2.5 2 1 0 2 2 2 0 IstB-like ATP binding protein MRP-L46 PF11788.3 KFX99486.1 - 9.4e-08 32.6 0.2 2.2e-07 31.5 0.1 1.6 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 KFX99486.1 - 0.00041 20.0 0.1 0.00072 19.2 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DUF737 PF05300.6 KFX99486.1 - 0.03 14.2 0.2 0.047 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) PRCC PF10253.4 KFX99487.1 - 3.2e-36 125.7 3.1 3.2e-36 125.7 2.1 2.6 3 0 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting SIN1 PF05422.7 KFX99488.1 - 1.9e-38 132.3 0.0 3.4e-19 68.7 0.0 3.0 2 2 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 KFX99488.1 - 0.00062 19.6 0.1 0.0015 18.3 0.1 1.7 1 0 0 1 1 1 1 GLUT4 regulating protein TUG RBD PF02196.10 KFX99488.1 - 0.066 12.9 0.1 0.19 11.5 0.1 1.8 2 0 0 2 2 2 0 Raf-like Ras-binding domain MFS_1 PF07690.11 KFX99489.1 - 8.5e-27 93.7 29.8 8.5e-27 93.7 20.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KFX99489.1 - 0.29 10.9 10.2 1.1 9.0 0.2 2.9 2 0 0 2 2 2 0 MFS_1 like family Cyclin PF08613.6 KFX99491.1 - 4.5e-38 130.9 0.2 1.2e-22 80.9 0.2 2.4 2 0 0 2 2 2 2 Cyclin DUF3602 PF12223.3 KFX99492.1 - 1.5e-14 54.1 15.5 3.6e-12 46.5 2.0 2.8 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) DUF2149 PF09919.4 KFX99492.1 - 0.58 10.2 3.0 0.92 9.6 2.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) VacA2 PF03077.9 KFX99492.1 - 1.5 8.5 4.6 3 7.4 0.6 2.3 2 0 0 2 2 2 0 Putative vacuolating cytotoxin PNPase_C PF12111.3 KFX99492.1 - 3.1 7.0 6.0 0.47 9.6 0.5 2.3 2 0 0 2 2 2 0 Polyribonucleotide phosphorylase C terminal Pkinase PF00069.20 KFX99494.1 - 1.4e-43 148.8 0.0 2.3e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 KFX99494.1 - 1.5e-30 105.6 0.0 3.5e-30 104.4 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A SWIB PF02201.13 KFX99494.1 - 2.2e-25 88.1 2.2 3e-25 87.6 0.1 2.4 3 0 0 3 3 3 1 SWIB/MDM2 domain Pkinase_Tyr PF07714.12 KFX99494.1 - 3.6e-23 81.9 0.0 3.7e-21 75.3 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase DEK_C PF08766.6 KFX99494.1 - 1.6e-13 50.1 0.5 3.6e-13 49.0 0.3 1.6 1 0 0 1 1 1 1 DEK C terminal domain PQQ_2 PF13360.1 KFX99494.1 - 0.00026 20.5 1.8 0.01 15.3 0.2 2.7 1 1 1 2 2 2 2 PQQ-like domain PQQ PF01011.16 KFX99494.1 - 0.0031 16.9 2.6 0.015 14.7 0.0 3.3 3 0 0 3 3 3 1 PQQ enzyme repeat APH PF01636.18 KFX99494.1 - 0.011 15.4 0.0 0.033 13.9 0.0 1.9 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KFX99494.1 - 0.012 14.6 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KFX99494.1 - 0.038 13.3 0.0 0.071 12.4 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Peptidase_C97 PF05903.9 KFX99496.1 - 4.2e-32 111.0 0.0 5.6e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 KFX99496.1 - 0.00019 21.3 0.0 0.00032 20.6 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF778 PF05608.7 KFX99496.1 - 0.073 13.0 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Ribosomal_S11 PF00411.14 KFX99497.1 - 7.9e-12 45.3 0.1 1.6e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S11 Tim44 PF04280.10 KFX99498.1 - 1.5e-32 112.6 0.0 3.7e-32 111.3 0.0 1.7 1 0 0 1 1 1 1 Tim44-like domain DUF1510 PF07423.6 KFX99498.1 - 0.029 13.7 15.4 0.067 12.5 10.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Dus PF01207.12 KFX99499.1 - 2.1e-60 204.1 0.0 2.7e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 KFX99499.1 - 0.00014 21.0 0.0 0.00021 20.3 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TMP-TENI PF02581.12 KFX99499.1 - 0.037 13.1 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI Na_Ca_ex PF01699.19 KFX99500.1 - 5e-40 136.3 31.0 4.2e-22 78.2 9.5 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein GAGA_bind PF06217.7 KFX99500.1 - 0.27 11.1 6.9 0.48 10.3 4.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DDRGK PF09756.4 KFX99500.1 - 0.84 9.0 13.3 1.4 8.2 9.2 1.2 1 0 0 1 1 1 0 DDRGK domain Peptidase_S49_N PF08496.5 KFX99500.1 - 4.2 7.1 7.8 10 5.9 5.4 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pkinase PF00069.20 KFX99501.1 - 2.5e-63 213.6 0.0 4.9e-63 212.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX99501.1 - 2.2e-35 121.9 0.0 2.6e-30 105.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFX99501.1 - 2.1e-05 23.6 0.0 0.014 14.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KFX99501.1 - 0.0045 16.7 0.0 0.0045 16.7 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KFX99501.1 - 0.0055 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KFX99501.1 - 0.066 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_4 PF12799.2 KFX99507.1 - 1.3e-16 59.7 11.1 5.7e-06 25.8 3.7 4.7 2 1 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFX99507.1 - 7.9e-11 41.5 13.3 8.9e-08 31.7 4.1 4.5 4 1 1 5 5 5 2 Leucine rich repeat LRR_1 PF00560.28 KFX99507.1 - 7.5e-10 37.4 11.7 0.59 10.3 0.6 6.7 5 1 0 5 5 5 4 Leucine Rich Repeat LRR_7 PF13504.1 KFX99507.1 - 3e-05 23.4 8.8 13 6.4 0.1 6.3 6 0 0 6 6 6 3 Leucine rich repeat LRR_6 PF13516.1 KFX99507.1 - 0.0033 17.3 11.2 28 5.1 0.0 5.9 3 1 2 5 5 5 1 Leucine Rich repeat Myb_DNA-bind_6 PF13921.1 KFX99509.1 - 4e-05 23.6 0.2 5.6e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KFX99509.1 - 0.027 14.5 2.8 0.077 13.0 1.9 1.8 1 1 0 1 1 1 0 Myb-like DNA-binding domain Sigma70_r4_2 PF08281.7 KFX99509.1 - 0.11 11.9 0.1 0.15 11.5 0.1 1.2 1 0 0 1 1 1 0 Sigma-70, region 4 DUF498 PF04430.9 KFX99510.1 - 2.5e-29 101.0 0.0 3.8e-29 100.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Alk_phosphatase PF00245.15 KFX99511.1 - 3.3e-109 365.3 0.0 4.1e-109 365.0 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 KFX99511.1 - 0.0012 18.2 0.0 0.0032 16.9 0.0 1.7 2 0 0 2 2 2 1 Metalloenzyme superfamily RskA PF10099.4 KFX99511.1 - 0.0013 18.4 0.1 0.004 16.9 0.0 1.8 2 0 0 2 2 2 1 Anti-sigma-K factor rskA Ribosomal_L34e PF01199.13 KFX99512.1 - 1.1e-37 128.1 3.9 1.4e-37 127.7 2.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L34e DUF1428 PF07237.6 KFX99512.1 - 0.074 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) FhuF_C PF11575.3 KFX99512.1 - 0.89 9.2 4.5 8.1 6.1 0.1 2.7 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain PROCN PF08083.6 KFX99513.1 - 1.2e-223 742.0 9.4 1.2e-223 742.0 6.5 1.6 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 KFX99513.1 - 2e-125 416.6 2.1 4e-125 415.7 1.4 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 KFX99513.1 - 5.3e-94 311.9 1.3 1.2e-93 310.7 0.9 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 KFX99513.1 - 1.6e-78 261.6 3.8 2.4e-78 261.0 1.7 2.0 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 KFX99513.1 - 3.4e-66 220.9 0.1 7.7e-66 219.8 0.1 1.7 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 KFX99513.1 - 5.6e-46 155.3 0.3 1.7e-45 153.7 0.0 2.1 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.4 KFX99513.1 - 2.6e-45 152.2 0.2 6.9e-45 150.8 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 OCD_Mu_crystall PF02423.10 KFX99513.1 - 0.14 10.8 1.4 0.24 10.1 0.9 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Myb_DNA-bind_6 PF13921.1 KFX99514.1 - 1.7e-12 47.2 0.0 4.6e-10 39.4 0.0 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KFX99514.1 - 1e-08 35.0 0.2 7.4e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain E1-E2_ATPase PF00122.15 KFX99515.1 - 7.3e-19 67.7 0.1 2.2e-18 66.1 0.1 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFX99515.1 - 2.4e-17 64.0 0.1 4e-16 60.0 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFX99515.1 - 1.9e-13 51.0 0.7 1.8e-12 47.8 0.5 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFX99515.1 - 1.1e-10 41.2 0.0 4.2e-10 39.4 0.0 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFX99515.1 - 0.001 18.7 0.0 0.0025 17.4 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase LSM PF01423.17 KFX99516.1 - 4.4e-14 51.7 0.4 5.7e-14 51.4 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KFX99516.1 - 0.035 14.0 0.1 0.061 13.2 0.1 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain PGP_phosphatase PF09419.5 KFX99517.1 - 8.4e-54 181.4 0.0 1.4e-53 180.7 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 KFX99517.1 - 2.2e-08 33.6 0.0 4.5e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Adipogenin PF15202.1 KFX99517.1 - 0.025 14.4 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 Adipogenin F-box-like PF12937.2 KFX99517.1 - 0.068 12.8 0.1 0.068 12.8 0.1 2.4 3 0 0 3 3 3 0 F-box-like ATG_C PF09333.6 KFX99518.1 - 0.07 13.2 0.0 4.2 7.5 0.0 2.1 2 0 0 2 2 2 0 ATG C terminal domain LTXXQ PF07813.7 KFX99519.1 - 0.042 14.3 0.1 0.065 13.7 0.1 1.4 1 0 0 1 1 1 0 LTXXQ motif family protein SBP_bac_7 PF03480.8 KFX99519.1 - 0.067 12.2 0.1 0.083 11.9 0.0 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 DUF3260 PF11658.3 KFX99519.1 - 0.12 10.5 0.1 0.13 10.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DUF2673 PF10880.3 KFX99519.1 - 0.17 11.9 0.8 0.74 9.9 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) AMP-binding PF00501.23 KFX99520.1 - 9.2e-40 136.2 0.0 1.2e-39 135.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Aminotran_1_2 PF00155.16 KFX99522.1 - 1e-60 205.6 0.0 1.6e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KFX99522.1 - 0.0088 15.2 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase Tmemb_18A PF09771.4 KFX99522.1 - 0.037 14.0 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 188 VIT1 PF01988.14 KFX99523.1 - 1.3e-25 90.1 0.1 1.7e-25 89.7 0.1 1.2 1 0 0 1 1 1 1 VIT family Epimerase PF01370.16 KFX99526.1 - 1.9e-07 30.7 0.2 2e-07 30.6 0.1 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX99526.1 - 3e-06 27.3 0.3 3e-06 27.3 0.2 1.0 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFX99526.1 - 3.9e-06 26.3 0.3 3.9e-06 26.2 0.2 1.0 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KFX99526.1 - 2.6e-05 23.0 0.1 2.9e-05 22.9 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KFX99526.1 - 0.0015 17.4 0.2 0.0016 17.4 0.1 1.0 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KFX99526.1 - 0.0047 16.8 0.5 0.0049 16.8 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase HTH_38 PF13936.1 KFX99526.1 - 0.028 13.9 0.0 0.038 13.5 0.0 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3493 PF11998.3 KFX99526.1 - 0.11 12.4 0.2 0.12 12.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3493) KR PF08659.5 KFX99526.1 - 0.11 12.1 0.3 0.11 12.1 0.2 1.1 1 0 0 1 1 1 0 KR domain MHYT PF03707.11 KFX99528.1 - 7e-15 54.8 21.2 6.6e-07 29.3 1.0 5.3 5 0 0 5 5 5 3 Bacterial signalling protein N terminal repeat DUF3377 PF11857.3 KFX99528.1 - 0.53 9.9 2.8 0.42 10.2 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Peptidase_A24 PF01478.13 KFX99528.1 - 0.6 10.3 9.1 1.9 8.6 2.0 2.8 2 0 0 2 2 2 0 Type IV leader peptidase family DUF1772 PF08592.6 KFX99528.1 - 1.4 8.6 17.4 0.019 14.7 3.1 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF1772) DUF4407 PF14362.1 KFX99528.1 - 8.9 5.1 7.6 17 4.2 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4131 PF13567.1 KFX99528.1 - 9.3 5.6 15.1 1 8.7 4.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF1684 PF07920.6 KFX99529.1 - 0.0069 16.2 0.1 5.2 6.9 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF1684) Sugar_tr PF00083.19 KFX99530.1 - 8.6e-99 331.1 18.2 9.8e-99 330.9 12.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX99530.1 - 8.7e-34 116.7 17.2 1.2e-33 116.2 11.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.13 KFX99531.1 - 1.1e-10 41.2 6.0 2.1e-10 40.3 4.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFX99531.1 - 5.1e-09 35.3 2.0 7.3e-09 34.8 1.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_2_C PF02836.12 KFX99532.1 - 3.4e-103 344.6 0.0 4.6e-103 344.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 KFX99532.1 - 2.2e-53 181.1 0.0 3.6e-53 180.3 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 KFX99532.1 - 4.2e-52 176.0 0.1 7.6e-52 175.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KFX99532.1 - 2.9e-18 66.2 0.2 7.4e-18 65.0 0.2 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 KFX99532.1 - 0.021 15.0 0.3 0.093 13.0 0.1 2.2 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain NmrA PF05368.8 KFX99533.1 - 2.6e-24 85.7 0.0 3.8e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX99533.1 - 2.9e-06 27.4 0.3 5.1e-06 26.6 0.2 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFX99533.1 - 0.0036 16.7 0.1 0.0083 15.5 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KFX99534.1 - 4.3e-10 39.7 0.0 6.1e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KFX99534.1 - 0.00027 20.4 0.0 0.00066 19.1 0.0 1.5 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX99534.1 - 0.00049 20.1 0.1 0.0011 18.9 0.0 1.7 2 1 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KFX99534.1 - 0.0012 18.1 0.0 0.0021 17.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 KFX99534.1 - 0.01 14.7 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.14 KFX99534.1 - 0.011 14.8 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KFX99534.1 - 0.013 15.5 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.1 KFX99534.1 - 0.045 13.5 0.1 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 KFX99534.1 - 0.095 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GMC_oxred_N PF00732.14 KFX99535.1 - 1.3e-52 178.7 0.0 1.7e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFX99535.1 - 5.4e-30 104.5 0.0 1.4e-29 103.1 0.0 1.8 2 0 0 2 2 1 1 GMC oxidoreductase DAO PF01266.19 KFX99535.1 - 1.1e-07 31.1 0.1 4.5e-05 22.5 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFX99535.1 - 1.2e-06 27.6 0.0 0.0003 19.7 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 KFX99535.1 - 4.7e-06 26.8 0.0 0.036 14.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFX99535.1 - 2.2e-05 23.5 0.1 3.5e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KFX99535.1 - 4.7e-05 23.3 0.0 0.023 14.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFX99535.1 - 0.00039 19.6 0.1 0.0008 18.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 KFX99535.1 - 0.00049 20.0 0.0 0.0014 18.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KFX99535.1 - 0.0013 18.5 0.1 0.056 13.2 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 KFX99535.1 - 0.006 15.0 0.1 0.012 14.0 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.9 KFX99535.1 - 0.011 14.3 0.1 0.016 13.8 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase K_oxygenase PF13434.1 KFX99535.1 - 0.14 11.0 0.0 1.5 7.6 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) ketoacyl-synt PF00109.21 KFX99536.1 - 4.5e-72 242.5 0.0 8.6e-72 241.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KFX99536.1 - 5.4e-61 206.6 0.7 9.4e-61 205.8 0.5 1.4 1 0 0 1 1 1 1 Acyl transferase domain Carn_acyltransf PF00755.15 KFX99536.1 - 1.4e-57 195.1 0.0 1.1e-54 185.5 0.0 2.2 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase KR PF08659.5 KFX99536.1 - 9.7e-54 181.7 0.0 5e-53 179.4 0.0 2.3 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 KFX99536.1 - 1.1e-44 152.2 0.1 2e-43 148.2 0.0 3.0 3 0 0 3 3 3 1 short chain dehydrogenase PS-DH PF14765.1 KFX99536.1 - 6.3e-44 150.3 0.0 9.9e-44 149.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 KFX99536.1 - 6.4e-38 129.2 0.0 1.7e-37 127.8 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KFX99536.1 - 7.7e-18 64.7 0.0 4e-17 62.5 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 KFX99536.1 - 2.1e-15 56.3 0.1 8.4e-15 54.4 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 KFX99536.1 - 5.5e-13 48.9 0.0 3.1e-12 46.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX99536.1 - 7.3e-12 45.1 0.0 1.8e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 KFX99536.1 - 2.2e-11 44.7 0.0 1.7e-10 41.8 0.0 2.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 KFX99536.1 - 8e-10 39.0 0.0 4.3e-09 36.7 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain PP-binding PF00550.20 KFX99536.1 - 5.3e-09 36.2 0.1 2e-08 34.3 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 KFX99536.1 - 1.2e-08 35.4 0.0 7e-08 33.0 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX99536.1 - 3.2e-05 23.1 0.0 6.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family 3Beta_HSD PF01073.14 KFX99536.1 - 0.001 17.8 0.0 0.0019 16.9 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_16 PF10294.4 KFX99536.1 - 0.0012 18.3 0.0 0.0025 17.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Thiolase_N PF00108.18 KFX99536.1 - 0.0028 16.6 0.0 0.007 15.3 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain RrnaAD PF00398.15 KFX99536.1 - 0.052 12.5 0.0 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Polysacc_synt_2 PF02719.10 KFX99536.1 - 0.21 10.4 0.0 0.41 9.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GFO_IDH_MocA PF01408.17 KFX99537.1 - 2.4e-23 82.9 0.0 5e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 KFX99537.1 - 0.018 15.4 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Ndc1_Nup PF09531.5 KFX99538.1 - 2.5 6.4 12.3 2.9 6.2 8.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.8 KFX99538.1 - 6.5 6.5 14.2 7.8 6.2 9.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Gln-synt_C PF00120.19 KFX99541.1 - 2.4e-61 207.1 0.0 2.9e-61 206.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KFX99541.1 - 4.3e-20 71.0 0.0 6.6e-20 70.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain ArfGap PF01412.13 KFX99543.1 - 9.5e-38 128.5 0.1 9.5e-38 128.5 0.0 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf UBA PF00627.26 KFX99543.1 - 0.0037 17.0 0.0 0.017 14.9 0.0 2.2 1 0 0 1 1 1 1 UBA/TS-N domain AA_permease PF00324.16 KFX99548.1 - 7.2e-120 400.5 35.9 8.1e-120 400.3 24.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFX99548.1 - 2.1e-31 108.9 40.2 2.5e-31 108.6 27.9 1.0 1 0 0 1 1 1 1 Amino acid permease AAA_33 PF13671.1 KFX99549.1 - 3.6e-21 75.5 0.0 4.5e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFX99549.1 - 4.1e-09 37.2 0.1 5.3e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFX99549.1 - 8.8e-08 32.5 0.0 1.2e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFX99549.1 - 7.5e-07 28.4 0.0 9.9e-07 28.0 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin SKI PF01202.17 KFX99549.1 - 0.00074 19.4 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase CPT PF07931.7 KFX99549.1 - 0.0034 17.0 0.0 0.0059 16.2 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein APS_kinase PF01583.15 KFX99549.1 - 0.009 15.6 0.1 2.3 7.8 0.0 2.2 2 0 0 2 2 2 2 Adenylylsulphate kinase DUF1792 PF08759.6 KFX99549.1 - 0.019 14.5 0.0 0.03 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1792) AAA_22 PF13401.1 KFX99549.1 - 0.032 14.3 0.1 0.043 13.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.15 KFX99549.1 - 0.042 12.5 0.1 0.044 12.4 0.1 1.4 1 1 0 1 1 1 0 G-protein alpha subunit NB-ARC PF00931.17 KFX99549.1 - 0.091 11.6 0.1 0.24 10.2 0.1 1.7 1 1 0 1 1 1 0 NB-ARC domain MobB PF03205.9 KFX99549.1 - 0.096 12.3 0.2 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 KFX99549.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NAD_binding_3 PF03447.11 KFX99549.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain AAA_10 PF12846.2 KFX99549.1 - 0.27 10.6 1.1 0.45 9.8 0.5 1.4 1 1 0 1 1 1 0 AAA-like domain MFS_1 PF07690.11 KFX99550.1 - 9.6e-30 103.4 26.5 3.1e-16 59.0 5.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFX99550.1 - 2.9e-10 39.1 18.4 0.00053 18.5 5.3 3.0 3 0 0 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.2 KFX99550.1 - 0.0067 16.1 9.9 0.053 13.3 0.2 3.9 3 1 1 4 4 4 2 MFS_1 like family ATG22 PF11700.3 KFX99550.1 - 0.41 9.0 22.0 0.0046 15.5 5.9 2.5 2 1 0 2 2 2 0 Vacuole effluxer Atg22 like Sugar_tr PF00083.19 KFX99550.1 - 0.8 8.2 28.2 38 2.6 19.1 2.7 1 1 1 2 2 2 0 Sugar (and other) transporter E1-E2_ATPase PF00122.15 KFX99550.1 - 1.3 8.0 5.3 7.5 5.5 3.7 2.2 1 1 0 1 1 1 0 E1-E2 ATPase OATP PF03137.15 KFX99550.1 - 1.4 6.9 7.7 0.12 10.3 0.8 2.2 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family WD40 PF00400.27 KFX99551.1 - 8.1e-31 104.7 0.3 3.3e-09 36.2 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KFX99551.1 - 0.00011 21.9 0.6 0.081 12.6 0.1 3.1 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFX99551.1 - 0.00027 19.2 0.1 0.00038 18.7 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 KFX99551.1 - 0.00059 18.7 0.3 0.35 9.6 0.1 2.4 1 1 2 3 3 3 2 Coatomer WD associated region Nucleoporin_N PF08801.6 KFX99551.1 - 0.004 15.9 0.0 0.094 11.4 0.0 2.3 1 1 1 2 2 2 1 Nup133 N terminal like PQQ_2 PF13360.1 KFX99551.1 - 0.0089 15.5 1.0 0.099 12.0 0.7 2.4 1 1 1 2 2 2 1 PQQ-like domain Peptidase_S9_N PF02897.10 KFX99551.1 - 0.042 12.4 1.4 0.081 11.4 0.4 1.7 1 1 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Gmad1 PF10647.4 KFX99551.1 - 0.048 13.0 1.0 0.17 11.2 0.1 1.9 1 1 1 2 2 2 0 Lipoprotein LpqB beta-propeller domain FTHFS PF01268.14 KFX99552.1 - 5e-257 853.3 0.5 6.9e-257 852.8 0.3 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 KFX99552.1 - 1.6e-67 225.6 1.8 1.6e-67 225.6 1.2 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KFX99552.1 - 1.8e-39 134.3 0.7 3.5e-39 133.4 0.5 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GTP_EFTU PF00009.22 KFX99552.1 - 0.011 15.1 0.1 0.034 13.5 0.0 1.8 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain HORMA PF02301.13 KFX99553.1 - 4.7e-49 166.6 0.4 5.4e-49 166.5 0.3 1.0 1 0 0 1 1 1 1 HORMA domain DUF1068 PF06364.7 KFX99553.1 - 0.017 14.7 0.3 0.027 14.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) DUF2066 PF09839.4 KFX99553.1 - 0.035 13.2 0.3 0.14 11.2 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2066) Alba PF01918.16 KFX99553.1 - 0.19 11.3 1.2 0.36 10.4 0.8 1.6 1 1 0 1 1 1 0 Alba SspB PF04386.8 KFX99553.1 - 0.64 9.6 5.2 1.5 8.4 0.0 2.3 1 1 1 2 2 2 0 Stringent starvation protein B GTP_EFTU PF00009.22 KFX99554.1 - 8.1e-48 162.3 0.0 1.7e-47 161.2 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 KFX99554.1 - 4e-39 132.8 6.6 6.4e-39 132.1 4.6 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 KFX99554.1 - 3.4e-19 68.4 0.0 6.1e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KFX99554.1 - 3e-07 30.4 0.1 6.4e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.17 KFX99554.1 - 8.9e-06 25.1 0.0 3.1e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.18 KFX99554.1 - 4.6e-05 23.3 0.1 0.00014 21.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFX99554.1 - 0.003 16.8 0.0 0.0073 15.5 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit EFG_II PF14492.1 KFX99554.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 Elongation Factor G, domain II FAD_binding_3 PF01494.14 KFX99556.1 - 6.3e-08 32.0 0.1 1.1e-05 24.6 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain bZIP_1 PF00170.16 KFX99557.1 - 8e-05 22.5 6.8 0.00013 21.8 4.7 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFX99557.1 - 0.014 15.1 9.0 0.023 14.5 6.3 1.2 1 0 0 1 1 1 0 Basic region leucine zipper Herpes_UL14 PF03580.9 KFX99558.1 - 0.083 12.6 0.1 0.13 12.0 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL14-like protein ATP-synt_B PF00430.13 KFX99559.1 - 0.51 10.1 5.5 0.32 10.8 2.1 1.9 2 1 0 2 2 2 0 ATP synthase B/B' CF(0) Ytp1 PF10355.4 KFX99563.1 - 3e-84 282.4 16.8 3e-84 282.4 11.6 1.6 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KFX99563.1 - 2.2e-32 110.7 1.5 2.2e-32 110.7 1.0 2.5 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) Ammonium_transp PF00909.16 KFX99564.1 - 6.9e-116 387.0 27.2 8.1e-116 386.7 18.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Pkinase PF00069.20 KFX99568.1 - 6.5e-70 235.2 0.0 1.1e-69 234.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFX99568.1 - 7.7e-30 103.8 0.0 1.3e-28 99.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFX99568.1 - 0.00043 19.3 0.0 0.82 8.5 0.0 3.0 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 KFX99568.1 - 0.031 13.3 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_23 PF13489.1 KFX99569.1 - 1.6e-09 37.7 0.0 2.8e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX99569.1 - 5.4e-09 36.4 0.0 1.1e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX99569.1 - 3e-05 24.4 0.0 0.00011 22.5 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX99569.1 - 3.7e-05 23.3 0.0 0.00026 20.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFX99569.1 - 0.00038 19.6 0.0 0.0014 17.7 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KFX99569.1 - 0.00063 20.0 0.0 0.0033 17.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX99569.1 - 0.0027 18.2 0.0 0.011 16.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain KH_1 PF00013.24 KFX99571.1 - 0.008 15.8 0.0 0.035 13.7 0.0 2.1 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 KFX99571.1 - 0.019 14.5 0.1 0.096 12.3 0.0 2.2 3 0 0 3 3 3 0 KH domain HSA PF07529.8 KFX99585.1 - 1.7e-15 56.5 1.6 1.7e-15 56.5 1.1 3.7 5 0 0 5 5 5 2 HSA Myb_DNA-bind_6 PF13921.1 KFX99585.1 - 1e-14 54.3 1.4 3.2e-14 52.7 1.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KFX99585.1 - 0.0022 17.9 0.7 0.0049 16.9 0.5 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4113 PF13438.1 KFX99585.1 - 0.065 12.8 0.2 0.16 11.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) PALP PF00291.20 KFX99586.1 - 3.8e-32 111.7 3.1 5.9e-32 111.1 2.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DAGK_cat PF00781.19 KFX99586.1 - 0.28 10.6 2.3 0.3 10.5 0.5 1.8 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain RhoGAP PF00620.22 KFX99590.1 - 1.1e-15 57.5 1.5 1.9e-15 56.7 0.1 2.0 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 KFX99590.1 - 1.1e-13 51.1 0.0 1e-12 48.0 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 KFX99590.1 - 1.4e-11 43.9 0.0 3.3e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) KIP1 PF07765.7 KFX99590.1 - 0.025 14.4 0.0 0.61 9.9 0.0 2.8 2 0 0 2 2 2 0 KIP1-like protein HR1 PF02185.11 KFX99590.1 - 0.056 13.1 0.4 0.21 11.3 0.3 2.0 1 0 0 1 1 1 0 Hr1 repeat Sec10 PF07393.6 KFX99591.1 - 1.6e-164 548.8 0.0 2e-164 548.5 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 KFX99591.1 - 1.8e-07 30.7 0.0 4e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFX99591.1 - 4.5e-06 26.1 0.0 8.4e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 F-box domain SNF2_N PF00176.18 KFX99592.1 - 5.2e-58 196.2 0.0 9.3e-58 195.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 KFX99592.1 - 6.9e-09 35.4 7.9 1.6e-08 34.2 5.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFX99592.1 - 4.9e-08 32.5 4.8 4.9e-08 32.5 3.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFX99592.1 - 1.4e-06 28.1 8.4 3.9e-06 26.7 5.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX99592.1 - 3.3e-06 26.7 7.1 8.9e-06 25.3 4.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFX99592.1 - 4.1e-06 26.3 7.0 4.1e-06 26.3 4.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFX99592.1 - 3.4e-05 23.8 2.8 0.00017 21.6 1.7 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger Helicase_C PF00271.26 KFX99592.1 - 0.0084 15.9 0.0 0.027 14.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_4 PF15227.1 KFX99592.1 - 0.14 12.0 7.8 0.29 11.0 5.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFX99592.1 - 0.26 11.0 4.3 0.82 9.4 3.0 1.9 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.1 KFX99592.1 - 0.27 10.8 3.4 0.62 9.6 2.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-P11 PF03854.9 KFX99592.1 - 0.69 9.4 8.8 0.14 11.6 3.2 2.0 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_4 PF14570.1 KFX99592.1 - 0.69 9.5 6.4 2.2 7.9 4.4 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Ribosomal_L38e PF01781.13 KFX99593.1 - 2.2e-32 110.6 2.5 2.6e-32 110.3 1.7 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family SAP PF02037.22 KFX99594.1 - 0.016 14.7 0.0 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 SAP domain Ish1 PF10281.4 KFX99594.1 - 0.12 12.4 1.2 0.26 11.4 0.8 1.7 1 1 0 1 1 1 0 Putative stress-responsive nuclear envelope protein NmrA PF05368.8 KFX99597.1 - 1e-59 201.6 0.3 1.3e-59 201.3 0.2 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFX99597.1 - 1.9e-16 60.5 0.7 3e-16 59.9 0.3 1.5 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFX99597.1 - 7.3e-07 28.1 0.2 1.1e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PUL PF08324.6 KFX99598.1 - 2.2e-44 151.2 0.0 2.9e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 KFX99598.1 - 2.1e-42 143.8 0.2 6.5e-42 142.2 0.4 1.7 2 0 0 2 2 2 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 KFX99598.1 - 1.5e-41 138.7 7.7 6.8e-07 28.9 0.0 8.5 9 0 0 9 9 9 6 WD domain, G-beta repeat WD40 PF00400.27 KFX99599.1 - 1.9e-38 128.9 5.1 6e-11 41.7 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat Autophagy_N PF03986.8 KFX99600.1 - 8.8e-21 74.2 1.3 1.1e-20 73.9 0.1 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 KFX99600.1 - 1.6e-19 69.7 0.0 2.9e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 KFX99600.1 - 4.4e-13 48.0 0.3 7.1e-13 47.4 0.2 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal PAH PF02671.16 KFX99601.1 - 0.00045 19.7 0.4 6.9 6.3 0.0 3.7 3 1 0 3 3 3 3 Paired amphipathic helix repeat F-box PF00646.28 KFX99602.1 - 0.09 12.4 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 F-box domain Pec_lyase_C PF00544.14 KFX99603.1 - 2.6e-45 154.3 0.9 4.8e-45 153.5 0.6 1.4 1 0 0 1 1 1 1 Pectate lyase PT-VENN PF04829.8 KFX99604.1 - 3.2 7.3 5.9 4.9 6.7 3.9 1.5 1 1 0 1 1 1 0 Pre-toxin domain with VENN motif ADH_N PF08240.7 KFX99605.1 - 1.6e-21 76.1 0.3 2.7e-21 75.3 0.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFX99605.1 - 5.4e-15 55.0 0.3 9e-15 54.3 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFX99605.1 - 2.3e-07 31.7 0.1 7.2e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 KFX99605.1 - 0.0058 16.2 0.0 0.0095 15.5 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF768 PF05589.6 KFX99605.1 - 0.16 11.9 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF768) adh_short_C2 PF13561.1 KFX99606.1 - 6.4e-27 94.8 0.5 7.8e-27 94.5 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFX99606.1 - 9.9e-18 64.6 5.9 1.3e-17 64.1 4.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Abhydrolase_3 PF07859.8 KFX99607.1 - 1.4e-48 165.2 0.0 7.7e-48 162.8 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 KFX99607.1 - 1.9e-12 46.7 2.5 6.2e-12 44.9 1.7 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KFX99607.1 - 0.0025 17.5 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pyr_redox_3 PF13738.1 KFX99608.1 - 8.3e-27 94.5 0.0 1.2e-26 94.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFX99608.1 - 7.4e-15 54.1 0.1 5.9e-14 51.1 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KFX99608.1 - 2.9e-11 42.8 0.0 2.5e-09 36.4 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KFX99608.1 - 4.4e-08 33.0 0.2 1.5e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFX99608.1 - 2.2e-06 27.7 0.0 0.0085 15.9 0.0 3.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFX99608.1 - 0.0038 16.3 0.0 0.014 14.4 0.0 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 KFX99608.1 - 0.0046 15.8 0.0 0.0085 14.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFX99608.1 - 0.0051 15.7 0.2 0.084 11.7 0.1 2.6 2 1 1 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 KFX99608.1 - 0.041 13.9 0.0 2.7 8.1 0.0 3.0 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 KFX99608.1 - 0.11 12.2 1.1 3.4 7.4 0.3 3.3 3 1 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KFX99608.1 - 0.14 11.1 0.3 2.2 7.2 0.3 2.1 1 1 1 2 2 2 0 FAD binding domain HI0933_like PF03486.9 KFX99608.1 - 0.17 10.3 0.2 0.37 9.2 0.2 1.5 2 0 0 2 2 2 0 HI0933-like protein 2-Hacid_dh_C PF02826.14 KFX99608.1 - 0.17 11.0 0.0 0.34 10.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 KFX99609.1 - 6.7e-22 78.5 0.0 4.8e-20 72.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFX99609.1 - 6e-20 70.9 0.1 1.1e-18 66.8 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KFX99609.1 - 6.5e-10 38.8 0.0 2e-09 37.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KFX99609.1 - 7e-08 31.7 0.1 1.4e-05 24.2 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 KFX99609.1 - 9.1e-06 25.0 0.0 0.0055 15.8 0.0 2.6 2 1 1 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 KFX99609.1 - 0.00023 20.9 0.1 0.59 9.9 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 KFX99609.1 - 0.12 11.2 0.0 1.5 7.5 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase adh_short PF00106.20 KFX99610.1 - 2.6e-20 73.0 0.0 4.3e-20 72.2 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFX99610.1 - 4.8e-09 36.1 0.0 1.2e-05 25.0 0.0 2.1 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 KFX99610.1 - 9.5e-06 25.5 0.0 0.0016 18.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFX99610.1 - 0.0044 16.4 0.0 0.009 15.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Lactamase_B PF00753.22 KFX99611.1 - 4.5e-09 36.2 0.9 6.7e-09 35.6 0.6 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFX99611.1 - 0.0018 17.8 0.1 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain MFS_1 PF07690.11 KFX99612.1 - 2.3e-37 128.5 38.4 2.3e-37 128.5 26.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 KFX99612.1 - 0.00072 19.5 0.4 0.00072 19.5 0.3 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF1228) Spherulin4 PF12138.3 KFX99613.1 - 4.9e-43 147.3 0.1 8.7e-43 146.5 0.1 1.4 1 0 0 1 1 1 1 Spherulation-specific family 4 Fungal_trans PF04082.13 KFX99613.1 - 8.9e-19 67.3 2.1 1.6e-18 66.5 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MSA-2c PF12238.3 KFX99613.1 - 0.09 12.4 0.0 0.09 12.4 0.0 2.3 2 1 1 3 3 3 0 Merozoite surface antigen 2c Mitofilin PF09731.4 KFX99615.1 - 0.24 10.0 9.9 0.3 9.6 6.9 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF605 PF04652.11 KFX99615.1 - 0.74 9.1 16.5 0.96 8.7 11.5 1.1 1 0 0 1 1 1 0 Vta1 like Herpes_TAF50 PF03326.8 KFX99615.1 - 6.4 5.6 18.7 8.6 5.1 13.0 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DNA_pol_viral_N PF00242.12 KFX99615.1 - 6.5 5.6 13.3 8.9 5.2 9.2 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain PNP_UDP_1 PF01048.15 KFX99616.1 - 0.00011 21.2 0.0 0.00028 19.9 0.0 1.7 1 1 0 1 1 1 1 Phosphorylase superfamily adh_short PF00106.20 KFX99619.1 - 3.2e-30 105.2 2.2 4.8e-30 104.6 1.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX99619.1 - 4.3e-30 105.2 0.5 5.7e-30 104.8 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFX99619.1 - 9.3e-14 51.4 0.3 1.5e-13 50.8 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFX99619.1 - 8.1e-06 25.4 0.4 1.7e-05 24.3 0.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.17 KFX99619.1 - 0.00077 19.1 0.1 0.0017 18.0 0.1 1.6 1 0 0 1 1 1 1 PA domain DFP PF04127.10 KFX99619.1 - 0.0098 15.5 0.8 0.067 12.7 0.4 2.2 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein HEM4 PF02602.10 KFX99619.1 - 0.015 14.5 0.2 0.25 10.5 0.0 2.5 1 1 0 2 2 2 0 Uroporphyrinogen-III synthase HemD Polysacc_synt_2 PF02719.10 KFX99619.1 - 0.065 12.1 0.1 0.089 11.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein zf-CCCH PF00642.19 KFX99620.1 - 4.5e-05 23.0 5.5 8.4e-05 22.1 3.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PWI PF01480.12 KFX99620.1 - 0.00092 19.2 0.0 0.003 17.6 0.0 1.7 1 1 0 1 1 1 1 PWI domain Myb_DNA-binding PF00249.26 KFX99621.1 - 0.024 14.6 0.0 0.065 13.3 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain GTP_EFTU PF00009.22 KFX99622.1 - 3.3e-61 206.0 0.2 4.5e-61 205.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KFX99622.1 - 3.1e-36 123.5 0.0 1.4e-35 121.4 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 KFX99622.1 - 1.8e-21 75.8 0.0 1e-20 73.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KFX99622.1 - 8.2e-13 48.2 0.9 1.5e-11 44.2 0.0 3.3 4 0 0 4 4 4 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KFX99622.1 - 1.3e-11 44.1 0.0 3.3e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KFX99622.1 - 1.7e-05 24.7 0.1 3.4e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Solute_trans_a PF03619.11 KFX99624.1 - 1.3e-104 349.3 3.4 1.6e-104 349.0 2.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha COG2 PF06148.6 KFX99625.1 - 0.041 13.7 0.3 0.097 12.5 0.2 1.6 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 WXG100 PF06013.7 KFX99625.1 - 0.067 13.1 0.6 0.16 12.0 0.1 1.9 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF1664 PF07889.7 KFX99625.1 - 0.32 10.7 1.9 0.56 10.0 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) bZIP_1 PF00170.16 KFX99628.1 - 0.0023 17.8 12.1 0.0053 16.6 8.4 1.6 1 1 0 1 1 1 1 bZIP transcription factor HALZ PF02183.13 KFX99628.1 - 0.012 15.2 1.7 0.024 14.3 1.1 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF904 PF06005.7 KFX99628.1 - 0.029 14.6 1.6 0.029 14.6 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) bZIP_2 PF07716.10 KFX99628.1 - 1.4 8.8 13.1 19 5.1 9.1 2.2 1 1 0 1 1 1 0 Basic region leucine zipper bZIP_Maf PF03131.12 KFX99628.1 - 2.1 8.7 9.2 3.9 7.8 6.4 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor eIF-3_zeta PF05091.7 KFX99630.1 - 2.7e-199 663.1 0.0 3.1e-199 662.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Arif-1 PF06770.6 KFX99631.1 - 0.013 14.8 0.5 0.013 14.8 0.3 1.8 2 0 0 2 2 2 0 Actin-rearrangement-inducing factor (Arif-1) Tyrosinase PF00264.15 KFX99633.1 - 7e-48 163.7 2.3 9.5e-48 163.2 1.6 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF1765 PF08578.5 KFX99635.1 - 1.4e-42 144.7 10.9 2.4e-42 143.9 7.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) F-box-like PF12937.2 KFX99637.1 - 0.00029 20.5 0.0 0.00087 18.9 0.0 1.9 1 0 0 1 1 1 1 F-box-like CytoC_RC PF02276.13 KFX99637.1 - 0.044 12.9 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit UvrD_C PF13361.1 KFX99645.1 - 1e-77 262.0 0.0 2.6e-77 260.6 0.0 1.6 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 KFX99645.1 - 1.8e-62 211.4 7.0 3.6e-62 210.4 1.7 2.5 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 KFX99645.1 - 1e-13 51.2 0.0 3.4e-13 49.6 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 KFX99645.1 - 1e-12 47.5 0.1 3.2e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KFX99645.1 - 6.1e-10 39.0 3.2 1.2e-05 25.0 0.2 3.2 3 0 0 3 3 3 2 AAA domain AAA_11 PF13086.1 KFX99645.1 - 3.9e-06 26.6 0.2 9.8e-06 25.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KFX99645.1 - 2e-05 24.2 0.0 1.2 8.6 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 KFX99645.1 - 0.011 15.4 0.1 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Helicase PhoH PF02562.11 KFX99645.1 - 0.029 13.6 0.2 3.6 6.7 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_22 PF13401.1 KFX99645.1 - 0.2 11.8 1.5 13 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Phytochelatin PF05023.9 KFX99646.1 - 0.093 11.6 0.1 0.11 11.4 0.1 1.1 1 0 0 1 1 1 0 Phytochelatin synthase SUI1 PF01253.17 KFX99647.1 - 0.017 14.9 0.6 0.62 9.9 0.5 2.2 2 0 0 2 2 2 0 Translation initiation factor SUI1 ELO PF01151.13 KFX99648.1 - 9.9e-09 34.8 0.7 9.9e-09 34.8 0.5 1.9 1 1 1 2 2 2 1 GNS1/SUR4 family Ubie_methyltran PF01209.13 KFX99649.1 - 4.9e-09 35.6 0.0 8.3e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KFX99649.1 - 6.4e-09 36.1 0.0 1.2e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX99649.1 - 1.3e-06 28.2 0.0 2.6e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFX99649.1 - 1.2e-05 25.5 0.0 2.1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX99649.1 - 0.00027 21.4 0.0 0.00047 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX99649.1 - 0.00028 20.4 0.0 0.00036 20.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFX99649.1 - 0.00035 20.5 0.1 0.00081 19.4 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX99649.1 - 0.0048 17.3 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Pho86 PF11124.3 KFX99649.1 - 0.073 12.0 0.0 2.4 7.0 0.0 2.1 2 0 0 2 2 2 0 Inorganic phosphate transporter Pho86 FAD_binding_8 PF08022.7 KFX99652.1 - 3.6e-17 62.1 0.0 7.4e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KFX99652.1 - 1.1e-13 51.3 5.1 1.5e-13 50.8 2.9 1.6 1 1 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KFX99652.1 - 9.8e-13 48.2 0.0 1.9e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain EF-hand_1 PF00036.27 KFX99652.1 - 0.00047 19.2 1.0 0.0011 18.1 0.7 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KFX99652.1 - 0.00065 19.7 0.4 0.0017 18.4 0.3 1.7 1 0 0 1 1 1 1 EF-hand domain pair FAD_binding_6 PF00970.19 KFX99652.1 - 0.014 15.5 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain EF-hand_5 PF13202.1 KFX99652.1 - 0.019 14.3 0.3 0.047 13.0 0.2 1.7 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 KFX99652.1 - 0.036 13.9 0.5 0.12 12.2 0.3 1.9 1 0 0 1 1 1 0 EF-hand domain zf-ribbon_3 PF13248.1 KFX99653.1 - 0.0044 16.1 9.3 0.0073 15.4 6.5 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 KFX99653.1 - 0.0071 16.1 5.0 0.012 15.4 3.5 1.4 1 0 0 1 1 1 1 Double zinc ribbon Ribonuc_red_2_N PF08471.5 KFX99653.1 - 0.099 12.7 0.0 0.24 11.4 0.0 1.6 2 0 0 2 2 2 0 Class II vitamin B12-dependent ribonucleotide reductase zinc_ribbon_2 PF13240.1 KFX99653.1 - 3.1 7.4 11.6 8.2 6.0 8.1 1.7 1 1 1 2 2 2 0 zinc-ribbon domain MARVEL PF01284.18 KFX99654.1 - 9.2e-10 38.5 14.4 1.5e-09 37.8 10.0 1.3 1 0 0 1 1 1 1 Membrane-associating domain DZR PF12773.2 KFX99654.1 - 0.00058 19.6 1.8 0.00095 18.9 1.2 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 KFX99654.1 - 0.00091 18.6 2.8 0.0024 17.3 1.9 1.7 1 1 1 2 2 2 2 zinc-ribbon domain zf-ribbon_3 PF13248.1 KFX99654.1 - 0.0039 16.3 2.6 0.0067 15.5 1.8 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DUF4149 PF13664.1 KFX99654.1 - 0.29 11.2 5.5 2.2 8.3 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4149) ABC2_membrane_5 PF13346.1 KFX99654.1 - 0.48 9.6 8.3 0.04 13.1 2.1 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein zf-DHHC PF01529.15 KFX99654.1 - 0.8 9.0 3.1 5.2 6.4 0.1 2.5 1 1 1 2 2 2 0 DHHC palmitoyltransferase Glyco_hydro_31 PF01055.21 KFX99655.1 - 2.4e-111 372.6 0.0 3e-111 372.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KFX99655.1 - 1.5e-17 63.2 0.2 3.1e-16 58.9 0.0 2.9 3 0 0 3 3 3 1 Galactose mutarotase-like CDC27 PF09507.5 KFX99656.1 - 0.0079 15.4 0.1 0.011 14.9 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 BAR PF03114.13 KFX99657.1 - 3.4e-62 209.9 7.0 4.2e-62 209.6 4.9 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KFX99657.1 - 1e-14 53.6 0.1 1.7e-14 52.9 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFX99657.1 - 3.9e-12 45.5 0.1 6.3e-12 44.8 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFX99657.1 - 3e-10 39.4 0.0 6.2e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 KFX99657.1 - 0.0011 18.3 9.7 0.067 12.4 0.0 2.2 2 0 0 2 2 2 2 Vps5 C terminal like APG6 PF04111.7 KFX99657.1 - 8.2 5.3 12.1 6.8 5.6 4.6 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Aminotran_5 PF00266.14 KFX99658.1 - 1.6e-94 316.7 0.0 2e-94 316.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KFX99658.1 - 4.4e-08 32.6 0.0 6.8e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KFX99658.1 - 9e-05 21.6 0.0 0.00026 20.1 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 KFX99658.1 - 0.0017 16.8 0.0 0.0027 16.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain CsbD PF05532.7 KFX99659.1 - 3.8e-15 55.3 28.4 7.7e-08 31.8 6.8 3.2 3 0 0 3 3 3 3 CsbD-like Peptidase_S15 PF02129.13 KFX99662.1 - 5.5e-37 127.6 1.0 3e-33 115.4 0.1 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 KFX99662.1 - 3.3e-22 79.4 0.0 5.9e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 KFX99662.1 - 7.9e-05 22.6 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX99662.1 - 0.02 14.6 0.1 0.098 12.4 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family VWA_3 PF13768.1 KFX99663.1 - 3.8e-25 88.4 0.0 7.5e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 KFX99663.1 - 7.6e-18 64.3 1.1 1.5e-17 63.3 0.1 2.0 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 KFX99663.1 - 2e-09 37.4 0.0 3.4e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KFX99663.1 - 6.3e-09 36.1 0.0 1.2e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 KFX99663.1 - 0.00012 21.4 0.0 0.00026 20.3 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.9 KFX99663.1 - 0.013 14.6 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.4 KFX99663.1 - 0.02 14.7 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus Oxysterol_BP PF01237.13 KFX99671.1 - 2.5e-89 299.2 0.0 2.9e-89 299.0 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein PIG-F PF06699.6 KFX99671.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 GPI biosynthesis protein family Pig-F F_bP_aldolase PF01116.15 KFX99672.1 - 6.1e-96 320.8 0.0 6.9e-96 320.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II MR_MLE_C PF13378.1 KFX99672.1 - 0.11 12.4 0.1 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 Enolase C-terminal domain-like COP-gamma_platf PF08752.5 KFX99672.1 - 0.15 11.9 0.1 0.54 10.0 0.0 1.8 2 0 0 2 2 2 0 Coatomer gamma subunit appendage platform subdomain Ribosomal_L9_N PF01281.14 KFX99673.1 - 1.6e-09 36.8 0.0 3.7e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.9 KFX99673.1 - 0.00023 21.2 1.3 0.81 9.8 0.0 3.5 4 0 0 4 4 4 2 Ribosomal protein L9, C-terminal domain Big_3 PF07523.7 KFX99673.1 - 0.092 12.8 0.1 0.24 11.5 0.1 1.7 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) UCH PF00443.24 KFX99674.1 - 5.1e-37 127.4 0.0 4.9e-30 104.5 0.0 2.9 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFX99674.1 - 8.2e-09 35.3 0.1 1.1e-07 31.5 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF559 PF04480.7 KFX99674.1 - 0.1 12.2 0.9 0.18 11.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF559) Yip1 PF04893.12 KFX99679.1 - 7.5e-06 25.5 17.2 0.0002 20.8 6.2 2.6 2 1 1 3 3 3 2 Yip1 domain 7TM_GPCR_Sra PF02117.11 KFX99680.1 - 0.54 8.8 6.2 0.22 10.0 2.7 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sra Sel1 PF08238.7 KFX99684.1 - 1.8e-19 69.7 9.6 2.8e-06 27.7 0.2 3.7 4 0 0 4 4 4 3 Sel1 repeat TraC PF07820.7 KFX99684.1 - 0.034 14.3 0.3 0.071 13.3 0.2 1.5 1 0 0 1 1 1 0 TraC-like protein TPR_14 PF13428.1 KFX99684.1 - 0.53 11.0 3.8 26 5.8 1.3 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat Complex1_LYR_1 PF13232.1 KFX99685.1 - 7.6e-08 32.4 0.6 1.8e-07 31.2 0.4 1.7 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KFX99685.1 - 2e-06 27.4 0.8 6.3e-06 25.8 0.5 1.8 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF2686 PF10887.3 KFX99685.1 - 0.019 13.6 0.0 0.03 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) MgsA_C PF12002.3 KFX99685.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal Ank_4 PF13637.1 KFX99687.1 - 3.4e-16 59.2 1.3 3.2e-10 40.2 0.6 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFX99687.1 - 2.5e-14 53.3 0.1 5.4e-06 26.6 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFX99687.1 - 3e-13 49.5 1.3 9.6e-05 22.5 0.5 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX99687.1 - 3.7e-11 42.1 1.3 0.0051 16.9 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 KFX99687.1 - 1e-09 37.6 5.0 0.00071 19.2 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 KFX99687.1 - 0.0008 19.0 0.4 0.0066 16.0 0.3 2.1 1 1 0 1 1 1 1 KilA-N domain DUF3074 PF11274.3 KFX99688.1 - 3e-35 121.5 0.3 3.7e-35 121.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Peptidase_M4_C PF02868.10 KFX99688.1 - 0.052 13.2 0.1 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Formyl_trans_N PF00551.14 KFX99689.1 - 8.7e-37 126.4 0.0 1e-36 126.1 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase MannoseP_isomer PF01050.13 KFX99689.1 - 0.11 12.1 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase DMRL_synthase PF00885.14 KFX99690.1 - 2.1e-39 134.4 0.1 5e-21 74.8 0.0 2.2 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase HTH_1 PF00126.22 KFX99691.1 - 0.045 13.4 1.1 0.077 12.7 0.7 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Cortexin PF11057.3 KFX99691.1 - 0.39 10.3 2.7 0.96 9.0 1.8 1.7 1 1 0 1 1 1 0 Cortexin of kidney Tubulin PF00091.20 KFX99718.1 - 4.1e-63 213.0 0.0 5.4e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFX99718.1 - 2.6e-33 114.7 0.0 4e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Lipase_3 PF01764.20 KFX99718.1 - 0.028 14.0 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Tubulin_3 PF14881.1 KFX99718.1 - 0.091 12.2 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Tannase PF07519.6 KFX99720.1 - 1.4e-101 340.5 0.1 1.6e-101 340.3 0.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 KFX99720.1 - 8.9e-05 22.4 0.0 0.00024 21.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFX99720.1 - 0.00078 18.7 0.0 0.011 15.0 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KFX99720.1 - 0.0096 15.5 0.1 0.028 13.9 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFX99721.1 - 6.8e-24 85.0 0.5 8.8e-24 84.6 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFX99721.1 - 2.8e-09 36.8 0.2 3.8e-09 36.4 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFX99721.1 - 3.9e-09 36.4 0.2 9.5e-09 35.1 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFX99721.1 - 9e-07 28.6 0.0 3.5e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 Putative lysophospholipase Chlorophyllase PF07224.6 KFX99721.1 - 0.0057 15.4 0.0 0.0084 14.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Zn_clus PF00172.13 KFX99722.1 - 1.1e-05 25.2 3.1 2.7e-05 23.9 2.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tn7_TnsC_Int PF11426.3 KFX99722.1 - 0.0031 17.1 0.6 0.063 13.0 0.1 2.5 2 0 0 2 2 2 1 Tn7 transposition regulator TnsC adh_short PF00106.20 KFX99723.1 - 3.1e-20 72.7 0.0 5.6e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFX99723.1 - 9.1e-15 55.0 0.0 1.2e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KFX99723.1 - 8.3e-06 25.1 0.0 5.5e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KFX99723.1 - 0.0005 20.1 0.1 0.00095 19.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding PRAI PF00697.17 KFX99723.1 - 0.0077 15.8 0.0 0.023 14.2 0.0 1.9 2 0 0 2 2 2 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase NmrA PF05368.8 KFX99723.1 - 0.012 14.8 0.1 0.022 13.9 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family Acetyltransf_1 PF00583.19 KFX99724.1 - 0.00015 21.7 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family But2 PF09792.4 KFX99725.1 - 4.8e-06 26.3 0.5 6.7e-06 25.9 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain RTTN_N PF14726.1 KFX99735.1 - 0.082 13.4 0.5 0.2 12.2 0.3 1.6 1 0 0 1 1 1 0 Rotatin, an armadillo repeat protein, centriole functioning Ribosomal_S5 PF00333.15 KFX99736.1 - 2.3e-28 97.7 2.1 2.3e-28 97.7 1.4 2.3 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 KFX99736.1 - 7.3e-22 76.4 0.0 1.4e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Rhodanese PF00581.15 KFX99737.1 - 4.2e-19 68.9 0.0 1.9e-10 41.0 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain zf-Apc11 PF12861.2 KFX99738.1 - 2.7e-45 152.1 11.8 3.2e-45 151.8 8.2 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KFX99738.1 - 4.1e-33 113.3 10.9 5.3e-33 112.9 7.6 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KFX99738.1 - 1.7e-08 34.1 16.7 1e-07 31.6 11.6 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFX99738.1 - 3.8e-05 23.2 12.5 0.00085 18.9 8.7 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFX99738.1 - 0.00011 21.7 14.9 0.00047 19.7 10.3 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFX99738.1 - 0.00043 20.2 14.6 0.003 17.5 10.1 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFX99738.1 - 0.00054 19.7 4.7 0.00054 19.7 3.3 2.3 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KFX99738.1 - 0.0012 18.3 3.1 0.0012 18.3 2.2 2.4 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 KFX99738.1 - 0.0018 18.2 16.8 0.03 14.2 11.7 3.0 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_5 PF14634.1 KFX99738.1 - 0.049 13.3 16.7 0.95 9.2 11.9 2.6 1 1 1 2 2 2 0 zinc-RING finger domain zf-Nse PF11789.3 KFX99738.1 - 0.05 13.1 6.5 0.089 12.3 4.5 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-HIT PF04438.11 KFX99738.1 - 0.06 13.0 4.7 0.062 12.9 0.7 2.3 2 0 0 2 2 2 0 HIT zinc finger DUF2256 PF10013.4 KFX99738.1 - 0.11 12.2 0.2 0.11 12.2 0.1 3.5 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) Opy2 PF09463.5 KFX99738.1 - 0.11 12.6 10.3 2.2 8.4 4.5 2.3 2 0 0 2 2 2 0 Opy2 protein Rtf2 PF04641.7 KFX99738.1 - 0.16 11.1 1.8 0.21 10.7 1.2 1.3 1 1 0 1 1 1 0 Rtf2 RING-finger zf-DBF PF07535.7 KFX99738.1 - 0.23 11.1 2.5 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 DBF zinc finger DUF329 PF03884.9 KFX99738.1 - 1.6 8.3 8.0 0.68 9.5 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF329) zinc-ribbons_6 PF07191.7 KFX99738.1 - 3.3 7.5 10.6 1.7 8.4 0.1 2.6 1 1 2 3 3 3 0 zinc-ribbons zf-RING-like PF08746.6 KFX99738.1 - 4 7.5 15.2 20 5.2 10.5 2.1 1 1 0 1 1 1 0 RING-like domain RINGv PF12906.2 KFX99738.1 - 4.2 7.4 13.1 13 5.9 8.8 2.1 1 1 0 1 1 1 0 RING-variant domain DZR PF12773.2 KFX99738.1 - 4.5 7.1 13.4 14 5.6 4.3 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-HC5HC2H PF13771.1 KFX99738.1 - 6.7 6.9 12.2 4.3 7.5 4.6 2.4 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KFX99738.1 - 7 6.7 10.9 3.6 7.6 4.2 2.2 1 1 1 2 2 2 0 PHD-zinc-finger like domain PHD PF00628.24 KFX99738.1 - 9.3 6.0 15.7 44 3.8 10.9 2.1 1 1 0 1 1 1 0 PHD-finger IBR PF01485.16 KFX99740.1 - 2.8e-06 27.1 33.0 0.00034 20.4 2.4 3.4 3 0 0 3 3 3 2 IBR domain CBM_1 PF00734.13 KFX99742.1 - 9.3e-12 44.3 11.9 9.3e-12 44.3 8.3 2.2 2 1 0 2 2 2 1 Fungal cellulose binding domain GATA PF00320.22 KFX99748.1 - 9e-15 53.7 5.5 1.9e-14 52.6 3.8 1.6 1 0 0 1 1 1 1 GATA zinc finger zf-RING_3 PF14369.1 KFX99748.1 - 0.22 11.5 1.9 0.49 10.4 1.3 1.6 1 0 0 1 1 1 0 zinc-finger zf-H2C2_2 PF13465.1 KFX99754.1 - 5.4e-19 67.4 26.7 8e-08 32.2 0.1 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 KFX99754.1 - 8.8e-19 66.6 29.1 7.8e-05 22.7 1.1 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFX99754.1 - 1.2e-09 37.7 27.1 0.0007 19.7 1.3 5.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KFX99754.1 - 0.012 15.7 12.5 1.6 8.9 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 KFX99754.1 - 0.017 15.4 1.1 0.017 15.4 0.7 3.3 1 1 2 3 3 3 0 TRAF-type zinc finger ZF-HD_dimer PF04770.7 KFX99754.1 - 4.3 7.4 10.3 15 5.6 0.0 3.4 2 2 1 3 3 3 0 ZF-HD protein dimerisation region CHORD PF04968.7 KFX99754.1 - 6.5 7.0 15.2 5 7.4 0.1 4.4 2 2 2 4 4 4 0 CHORD Peptidase_M41 PF01434.13 KFX99755.1 - 3.4e-71 239.0 4.6 5.2e-70 235.2 2.7 2.2 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 KFX99755.1 - 4.6e-42 143.3 0.0 1.2e-41 141.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFX99755.1 - 1.4e-05 25.1 0.7 0.00014 21.8 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 KFX99755.1 - 2.4e-05 23.2 0.0 4.9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 KFX99755.1 - 4e-05 23.3 0.0 0.00014 21.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFX99755.1 - 4.2e-05 23.7 0.1 0.029 14.5 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFX99755.1 - 0.00012 22.9 0.0 0.00029 21.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KFX99755.1 - 0.00049 19.2 0.0 0.0011 18.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KFX99755.1 - 0.001 18.9 0.0 0.0038 17.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFX99755.1 - 0.002 17.8 0.4 0.0054 16.4 0.3 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KFX99755.1 - 0.0022 17.4 0.1 0.0066 15.8 0.1 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 KFX99755.1 - 0.0046 16.3 1.1 0.08 12.3 0.4 2.6 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFX99755.1 - 0.0091 15.1 1.1 0.026 13.6 0.3 2.0 1 1 1 2 2 2 1 Zeta toxin Mg_chelatase PF01078.16 KFX99755.1 - 0.02 14.0 0.2 0.042 13.0 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 KFX99755.1 - 0.023 14.5 0.0 0.073 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 KFX99755.1 - 0.033 14.1 0.0 0.092 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KFX99755.1 - 0.068 12.0 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 KFX99755.1 - 0.1 12.5 0.0 0.3 10.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 KFX99755.1 - 0.12 12.0 0.3 1.2 8.7 0.1 2.2 2 0 0 2 2 2 0 NACHT domain Beta_protein PF14350.1 KFX99755.1 - 0.12 11.4 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Beta protein AAA_18 PF13238.1 KFX99755.1 - 0.13 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain TFIIB PF00382.14 KFX99756.1 - 2e-31 107.6 1.9 8.7e-18 63.9 0.1 2.9 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.8 KFX99756.1 - 1.1e-20 73.6 2.2 5.7e-20 71.3 0.2 2.4 2 0 0 2 2 2 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 KFX99756.1 - 5.8e-07 29.1 0.3 0.0054 16.2 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain TF_Zn_Ribbon PF08271.7 KFX99756.1 - 3.4 7.0 7.9 0.14 11.5 0.5 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding Cpn10 PF00166.16 KFX99757.1 - 1e-25 89.4 0.0 1.2e-25 89.3 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pkinase PF00069.20 KFX99758.1 - 3e-59 200.3 0.0 4.1e-59 199.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ribosomal_L11_N PF03946.9 KFX99758.1 - 1.1e-25 88.8 0.2 5.6e-25 86.5 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KFX99758.1 - 1.9e-22 79.1 0.2 4.5e-22 77.9 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Pkinase_Tyr PF07714.12 KFX99758.1 - 1.6e-20 73.2 0.0 4.2e-20 71.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KFX99758.1 - 0.01 15.5 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Svf1 PF08622.5 KFX99759.1 - 9.7e-124 412.5 0.3 1.2e-123 412.2 0.2 1.1 1 0 0 1 1 1 1 Svf1-like Glyco_hydro_31 PF01055.21 KFX99761.1 - 1.8e-34 119.3 0.1 2.1e-34 119.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 TPR_11 PF13414.1 KFX99765.1 - 5.5e-05 22.7 0.6 0.00052 19.6 0.2 2.2 1 1 1 2 2 2 1 TPR repeat TPR_17 PF13431.1 KFX99765.1 - 0.074 13.2 0.1 0.39 11.0 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA PF00004.24 KFX99766.1 - 5e-20 72.0 0.0 8.9e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFX99766.1 - 0.0028 17.7 0.1 0.013 15.6 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KFX99766.1 - 0.032 14.2 0.0 0.08 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 KFX99766.1 - 0.098 12.4 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 KFX99766.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase CcmD PF04995.9 KFX99767.1 - 0.016 14.9 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF606 PF04657.8 KFX99767.1 - 0.035 14.1 0.0 0.05 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF606 DUF1689 PF07954.6 KFX99767.1 - 0.046 13.5 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) DUF2615 PF11027.3 KFX99767.1 - 0.046 13.6 0.7 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) Lysis_S PF04971.7 KFX99767.1 - 0.11 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Lysis protein S Methyltransf_25 PF13649.1 KFX99768.1 - 1.3e-10 41.5 0.0 3.6e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX99768.1 - 0.0005 20.5 0.0 0.00087 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX99768.1 - 0.005 17.3 0.0 0.0098 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX99768.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 KFX99769.1 - 1.6e-63 214.8 0.0 2e-63 214.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 KFX99770.1 - 2.9e-80 269.7 0.0 3.8e-80 269.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFX99770.1 - 1e-06 29.5 0.2 3.8e-06 27.7 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain SHQ1 PF04925.10 KFX99770.1 - 0.12 11.7 0.1 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 SHQ1 protein p450 PF00067.17 KFX99771.1 - 1.4e-54 185.3 0.0 1.9e-54 184.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SoxZ PF08770.6 KFX99771.1 - 0.00094 18.5 0.0 0.0019 17.5 0.0 1.5 1 0 0 1 1 1 1 Sulphur oxidation protein SoxZ Aminotran_1_2 PF00155.16 KFX99772.1 - 3.4e-38 131.5 0.0 4.4e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KFX99772.1 - 8.4e-09 34.6 0.0 1.1e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KFX99772.1 - 9.3e-07 27.4 0.0 1.3e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KFX99772.1 - 5e-05 22.5 0.0 7.1e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.2 KFX99772.1 - 0.0022 16.6 0.0 0.003 16.1 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase MTS PF05175.9 KFX99773.1 - 1.1e-19 70.4 0.0 1.4e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KFX99773.1 - 1.4e-11 44.4 0.0 2e-11 43.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFX99773.1 - 9.7e-10 39.0 0.0 1.6e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFX99773.1 - 6.7e-09 35.5 0.0 8.2e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFX99773.1 - 3.5e-08 33.3 0.0 7e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFX99773.1 - 2.4e-06 27.9 0.0 3.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFX99773.1 - 2.6e-06 26.7 0.0 4.8e-06 25.9 0.0 1.3 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 KFX99773.1 - 3.8e-06 27.1 0.0 7.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFX99773.1 - 9.9e-05 22.7 0.0 0.00023 21.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.9 KFX99773.1 - 0.00012 21.3 0.0 0.0002 20.5 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_16 PF10294.4 KFX99773.1 - 0.00039 19.9 0.0 0.00059 19.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_15 PF09445.5 KFX99773.1 - 0.009 15.5 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 KFX99773.1 - 0.038 13.5 0.1 0.1 12.2 0.0 1.6 1 1 1 2 2 2 0 Met-10+ like-protein CMAS PF02353.15 KFX99773.1 - 0.042 12.9 0.0 0.25 10.3 0.0 1.9 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 KFX99773.1 - 0.054 12.6 0.1 0.8 8.7 0.0 2.0 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family NodS PF05401.6 KFX99773.1 - 0.075 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) UPF0020 PF01170.13 KFX99773.1 - 0.17 11.4 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 TENA_THI-4 PF03070.11 KFX99774.1 - 1.6e-11 44.4 0.0 5.8e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 TENA/THI-4/PQQC family AMP-binding PF00501.23 KFX99775.1 - 1.7e-79 267.1 0.0 3e-79 266.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KFX99775.1 - 2.8e-45 154.4 0.1 4.2e-45 153.8 0.1 1.3 1 0 0 1 1 1 1 Condensation domain NAD_binding_4 PF07993.7 KFX99775.1 - 1.6e-41 141.8 0.1 2.6e-41 141.1 0.1 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 KFX99775.1 - 4.2e-18 65.3 0.1 2.9e-11 43.4 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.16 KFX99775.1 - 6.2e-08 32.3 0.0 1.4e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFX99775.1 - 3.1e-06 26.0 0.0 8.8e-06 24.6 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Pkinase PF00069.20 KFX99792.1 - 2.7e-09 36.5 0.0 1.2e-08 34.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain DUF1768 PF08719.6 KFX99793.1 - 3e-48 163.5 0.0 3.6e-48 163.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) RepC PF06504.6 KFX99793.1 - 0.059 12.3 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Replication protein C (RepC) CMV_1a PF12467.3 KFX99794.1 - 0.97 9.7 7.4 2.5 8.4 5.2 1.6 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family Ribophorin_I PF04597.9 KFX99795.1 - 3.6e-77 259.7 0.1 4e-77 259.5 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I DNA_pol_phi PF04931.8 KFX99796.1 - 4.3e-60 203.4 10.8 4.3e-60 203.4 7.5 1.9 2 1 0 2 2 2 1 DNA polymerase phi DUF2823 PF11034.3 KFX99797.1 - 6.8e-31 106.2 8.6 7.4e-31 106.0 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) Tombus_movement PF05318.7 KFX99797.1 - 6.6 7.4 7.3 17 6.1 5.1 1.7 1 1 0 1 1 1 0 Tombusvirus movement protein Rhodanese PF00581.15 KFX99798.1 - 2.1e-12 47.4 0.0 5e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain DUF4110 PF13422.1 KFX99802.1 - 4.9e-11 42.3 0.7 4.9e-11 42.3 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4110) Proteasome PF00227.21 KFX99803.1 - 7.4e-47 159.0 0.1 9.3e-47 158.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 KFX99803.1 - 7.4e-13 47.5 2.2 1.5e-12 46.5 1.5 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal CTDII PF01556.13 KFX99804.1 - 5.2e-20 71.1 0.1 2.5e-17 62.5 0.0 3.0 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 KFX99804.1 - 2.1e-19 69.0 1.4 6.1e-19 67.5 1.0 1.8 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.13 KFX99804.1 - 8.6e-14 51.0 0.0 1.5e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DnaJ_CXXCXGXG PF00684.14 KFX99804.1 - 6.3e-13 48.5 19.5 6.3e-13 48.5 13.5 2.5 2 0 0 2 2 2 1 DnaJ central domain Zn_clus PF00172.13 KFX99804.1 - 7.5e-07 28.9 8.5 7.5e-07 28.9 5.9 2.8 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 KFX99805.1 - 1.8e-06 27.5 0.1 0.27 11.2 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 KFX99805.1 - 0.051 13.3 0.0 0.53 10.0 0.0 2.3 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region FKBP_C PF00254.23 KFX99811.1 - 1.2e-30 105.3 0.0 3.9e-30 103.7 0.0 1.9 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FA_desaturase PF00487.19 KFX99811.1 - 5.6 6.3 4.5 8.4 5.7 3.1 1.2 1 0 0 1 1 1 0 Fatty acid desaturase IMS PF00817.15 KFX99812.1 - 4.2e-41 140.2 0.0 7.8e-41 139.3 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family CSTF2_hinge PF14327.1 KFX99812.1 - 1.1e-26 92.6 0.4 1.1e-26 92.6 0.3 2.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 KFX99812.1 - 8.9e-22 76.5 0.0 2.2e-21 75.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IMS_C PF11799.3 KFX99812.1 - 2e-17 63.3 0.0 6.3e-17 61.7 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 KFX99812.1 - 3.5e-15 55.8 2.1 4.4e-06 26.5 0.1 3.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4414) RRM_6 PF14259.1 KFX99812.1 - 4.4e-15 55.4 0.0 1.1e-14 54.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) BRCT PF00533.21 KFX99812.1 - 5.1e-09 36.1 0.0 3.3e-08 33.5 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RRM_5 PF13893.1 KFX99812.1 - 5.1e-07 29.4 0.0 9.6e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 KFX99812.1 - 8.2e-07 28.2 4.4 8.2e-07 28.2 3.0 2.5 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal PTCB-BRCT PF12738.2 KFX99812.1 - 5.2e-05 23.0 0.0 0.00014 21.6 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.3 KFX99812.1 - 0.00013 21.7 0.3 0.0011 18.9 0.0 2.7 2 0 0 2 2 2 1 IMS family HHH motif HHH_5 PF14520.1 KFX99812.1 - 0.1 12.7 0.0 0.35 11.0 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF1805 PF08827.6 KFX99812.1 - 0.19 11.5 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) Band_7 PF01145.20 KFX99813.1 - 5.4e-23 81.8 2.4 7.6e-23 81.3 1.7 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Methyltransf_5 PF01795.14 KFX99813.1 - 0.14 11.3 2.7 0.21 10.8 1.9 1.3 1 1 0 1 1 1 0 MraW methylase family ubiquitin PF00240.18 KFX99814.1 - 8.3e-26 89.1 0.2 9.1e-26 89.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KFX99814.1 - 1.5e-15 56.6 0.2 1.6e-15 56.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KFX99814.1 - 2.7e-05 24.3 0.0 7.9e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain SnoaL PF07366.7 KFX99815.1 - 0.0023 17.4 0.0 0.0042 16.6 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase DLH PF01738.13 KFX99815.1 - 0.16 11.2 0.0 4.4 6.5 0.0 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family Elongin_A PF06881.6 KFX99816.1 - 5e-22 78.3 2.3 1.2e-21 77.1 1.0 2.0 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DEAD PF00270.24 KFX99827.1 - 1.1e-31 109.6 0.1 3.9e-31 107.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFX99827.1 - 3.2e-23 81.3 0.1 5.9e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 KFX99827.1 - 0.0059 16.3 0.1 0.021 14.5 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain FCH PF00611.18 KFX99828.1 - 2.6e-23 81.9 0.0 2.6e-23 81.9 0.0 2.7 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 KFX99828.1 - 3.4e-23 80.9 1.0 6.6e-14 51.2 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KFX99828.1 - 8e-17 60.3 0.4 2.6e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.17 KFX99828.1 - 1.2e-14 53.6 5.6 2e-14 53.0 3.9 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.12 KFX99828.1 - 1.1e-07 31.1 0.1 0.007 15.8 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 KFX99828.1 - 1e-05 25.6 1.0 0.00024 21.1 0.2 2.6 2 0 0 2 2 2 1 Bacterial SH3 domain C1_2 PF03107.11 KFX99828.1 - 0.53 10.4 7.8 0.9 9.7 5.4 1.3 1 0 0 1 1 1 0 C1 domain DUF342 PF03961.8 KFX99828.1 - 3.5 5.9 6.9 0.41 9.0 1.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Glyco_hydro_72 PF03198.9 KFX99829.1 - 3.1e-129 430.4 0.1 3.8e-129 430.1 0.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 KFX99829.1 - 0.00027 20.2 0.0 0.002 17.3 0.0 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1349 PF07081.6 KFX99830.1 - 4e-25 88.2 0.1 5.2e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Asp PF00026.18 KFX99838.1 - 4.1e-48 164.2 0.8 6.8e-48 163.5 0.6 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFX99838.1 - 5.4e-06 26.4 0.3 9.8e-06 25.6 0.2 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KFX99838.1 - 0.0046 17.4 0.6 0.66 10.5 0.1 3.2 2 1 0 2 2 2 1 Aspartyl protease ADH_zinc_N PF00107.21 KFX99839.1 - 1.4e-16 60.2 0.0 2.7e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFX99839.1 - 1.7e-06 27.7 1.0 7.6e-06 25.6 0.0 2.5 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain Peptidase_C25_C PF03785.9 KFX99839.1 - 0.087 12.6 1.3 0.9 9.3 0.3 2.9 3 0 0 3 3 3 0 Peptidase family C25, C terminal ig-like domain CAP59_mtransfer PF11735.3 KFX99840.1 - 5.4e-63 212.4 0.0 7.6e-63 211.9 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Amidohydro_1 PF01979.15 KFX99841.1 - 1.1e-33 117.3 0.0 2.1e-33 116.3 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family PPR_2 PF13041.1 KFX99841.1 - 1.4e-20 73.0 7.8 3e-06 27.1 0.1 7.9 6 2 3 9 9 8 4 PPR repeat family PPR_3 PF13812.1 KFX99841.1 - 1.8e-20 71.4 5.6 0.0032 17.6 0.0 10.5 11 0 0 11 11 10 3 Pentatricopeptide repeat domain PPR PF01535.15 KFX99841.1 - 4.7e-12 45.0 10.5 0.24 11.4 0.0 9.4 10 0 0 10 10 10 4 PPR repeat Amidohydro_3 PF07969.6 KFX99841.1 - 6.2e-10 38.8 0.0 1.9e-07 30.7 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase family Zn_clus PF00172.13 KFX99841.1 - 1.6e-07 31.1 9.3 2.7e-07 30.3 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_4 PF13147.1 KFX99841.1 - 9.6e-07 29.0 0.4 3e-05 24.1 0.3 2.8 1 1 0 1 1 1 1 Amidohydrolase PPR_1 PF12854.2 KFX99841.1 - 1.2e-05 24.6 0.0 0.37 10.3 0.0 4.3 4 0 0 4 4 4 1 PPR repeat Amidohydro_5 PF13594.1 KFX99841.1 - 0.00016 21.4 0.1 0.00045 19.9 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase ECSIT PF06239.6 KFX99841.1 - 0.032 13.0 0.1 0.32 9.8 0.0 2.3 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway Fungal_trans PF04082.13 KFX99841.1 - 0.056 12.3 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF4099 PF13351.1 KFX99841.1 - 0.2 11.5 0.0 13 5.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4099) TPR_1 PF00515.23 KFX99841.1 - 2 8.1 6.1 31 4.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFX99841.1 - 5.2 7.0 6.2 46 4.1 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat PMEI PF04043.10 KFX99842.1 - 0.0034 17.2 1.3 0.012 15.4 0.9 1.9 1 0 0 1 1 1 1 Plant invertase/pectin methylesterase inhibitor FA_hydroxylase PF04116.8 KFX99852.1 - 4.2e-12 46.4 26.2 5.2e-12 46.1 12.2 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily Lysozyme_like PF13702.1 KFX99852.1 - 0.027 13.9 0.3 0.042 13.3 0.2 1.2 1 0 0 1 1 1 0 Lysozyme-like T4SS PF07996.6 KFX99875.1 - 0.0016 18.3 1.9 0.0016 18.3 1.3 1.4 1 1 0 1 1 1 1 Type IV secretion system proteins HSBP1 PF06825.7 KFX99875.1 - 0.009 15.5 0.6 5.2 6.7 0.2 2.5 2 1 0 2 2 2 2 Heat shock factor binding protein 1 UreE_C PF05194.7 KFX99875.1 - 0.027 14.5 1.2 0.047 13.7 0.4 1.7 2 0 0 2 2 2 0 UreE urease accessory protein, C-terminal domain DASH_Dad2 PF08654.5 KFX99875.1 - 0.029 14.3 0.7 0.63 10.0 0.1 2.2 1 1 1 2 2 2 0 DASH complex subunit Dad2 COG5 PF10392.4 KFX99875.1 - 0.039 13.9 2.5 0.33 10.9 0.5 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Cauli_AT PF03233.8 KFX99875.1 - 0.041 13.6 0.8 0.091 12.4 0.4 1.5 1 1 0 1 1 1 0 Aphid transmission protein DUF327 PF03885.8 KFX99875.1 - 0.054 13.3 2.3 0.27 11.0 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF327) FlaC_arch PF05377.6 KFX99875.1 - 0.075 12.9 0.6 0.27 11.1 0.1 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Adeno_PIX PF03955.9 KFX99875.1 - 0.11 13.0 3.3 0.6 10.6 0.1 2.1 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF2365 PF10157.4 KFX99875.1 - 0.12 12.2 1.8 0.23 11.3 1.0 1.7 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2365) DUF745 PF05335.8 KFX99875.1 - 0.19 11.2 9.1 0.71 9.3 6.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF745) CorA PF01544.13 KFX99875.1 - 0.25 10.3 5.1 1.1 8.2 3.6 1.8 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Snapin_Pallidin PF14712.1 KFX99875.1 - 0.35 11.1 3.7 1.5 9.1 2.0 2.2 1 1 1 2 2 2 0 Snapin/Pallidin IncA PF04156.9 KFX99875.1 - 0.67 9.5 7.3 0.99 8.9 5.1 1.3 1 0 0 1 1 1 0 IncA protein phage_tail_N PF08400.5 KFX99875.1 - 0.86 9.3 3.2 0.65 9.7 0.3 2.1 2 1 1 3 3 3 0 Prophage tail fibre N-terminal Syntaxin-6_N PF09177.6 KFX99875.1 - 3 8.2 6.1 13 6.2 0.6 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Lipase_3 PF01764.20 KFX99876.1 - 1.7e-18 66.6 0.0 6.4e-15 54.9 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) Acetyltransf_7 PF13508.1 KFX99877.1 - 2.9e-11 43.3 0.2 5.3e-11 42.5 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFX99877.1 - 3.9e-11 42.8 0.1 6.8e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Tetraspannin PF00335.15 KFX99877.1 - 4.4e-09 35.9 2.8 7.3e-09 35.2 1.9 1.3 1 0 0 1 1 1 1 Tetraspanin family Acetyltransf_9 PF13527.1 KFX99877.1 - 0.001 18.8 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFX99877.1 - 0.0071 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF2721 PF11026.3 KFX99877.1 - 0.047 13.3 2.4 0.097 12.3 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) zf-RING_2 PF13639.1 KFX99878.1 - 9.9e-14 50.8 2.5 1.7e-13 50.1 1.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFX99878.1 - 7e-09 35.6 0.3 1.5e-08 34.6 0.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KFX99878.1 - 4.8e-08 32.9 1.4 1.2e-07 31.6 1.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFX99878.1 - 3.1e-07 29.9 1.0 5.1e-07 29.3 0.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFX99878.1 - 9.6e-07 28.3 1.2 1.9e-06 27.3 0.9 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFX99878.1 - 5.1e-06 26.1 0.2 1.5e-05 24.6 0.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 KFX99878.1 - 3.2e-05 23.4 1.2 0.00012 21.6 0.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFX99878.1 - 0.002 17.9 3.0 0.0093 15.8 2.1 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 KFX99878.1 - 0.0067 16.3 1.8 0.024 14.5 1.3 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 KFX99878.1 - 0.02 14.7 0.6 0.02 14.7 0.4 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn-ribbon_8 PF09723.5 KFX99878.1 - 0.16 11.9 1.6 17 5.4 0.0 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Prok-RING_4 PF14447.1 KFX99878.1 - 0.33 10.5 4.4 0.24 10.9 0.4 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KFX99878.1 - 1.1 8.9 7.4 26 4.5 5.6 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Ribosomal_L14e PF01929.12 KFX99879.1 - 1.3e-28 99.1 2.2 2e-28 98.5 1.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 KFX99879.1 - 1.5e-05 24.4 1.0 3e-05 23.5 0.7 1.5 1 0 0 1 1 1 1 KOW motif NAC PF01849.13 KFX99880.1 - 6.8e-25 86.3 0.2 6.4e-24 83.2 0.1 2.1 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 KFX99880.1 - 0.0092 15.8 0.2 0.019 14.8 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Ribosomal_S13 PF00416.17 KFX99880.1 - 0.11 13.0 0.7 1.4 9.4 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S13/S18 SelP_N PF04592.9 KFX99880.1 - 1.3 8.3 6.5 2.5 7.4 4.5 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region CDC45 PF02724.9 KFX99880.1 - 5 5.0 11.7 0.098 10.6 3.3 1.5 2 0 0 2 2 2 0 CDC45-like protein Mt_ATP-synt_D PF05873.7 KFX99881.1 - 1.2e-18 67.3 0.7 1.5e-18 66.9 0.5 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF4515 PF14988.1 KFX99881.1 - 0.012 15.2 2.1 0.18 11.4 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) E3_UbLigase_R4 PF13764.1 KFX99881.1 - 0.037 11.9 0.5 0.043 11.7 0.4 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 CCDC155 PF14662.1 KFX99881.1 - 0.042 13.4 2.7 0.15 11.6 0.7 2.0 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 DUF3544 PF12064.3 KFX99881.1 - 0.077 12.7 0.2 0.1 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3544) V_ATPase_I PF01496.14 KFX99881.1 - 0.12 10.1 1.1 0.14 9.9 0.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lectin_N PF03954.9 KFX99881.1 - 0.22 10.9 1.3 0.34 10.2 0.3 1.7 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Fib_alpha PF08702.5 KFX99881.1 - 0.3 11.1 3.4 0.31 11.1 1.0 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF1319 PF07028.6 KFX99881.1 - 0.33 11.1 4.0 0.63 10.2 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) Syntaxin PF00804.20 KFX99881.1 - 0.77 9.9 5.7 0.74 10.0 1.4 2.0 1 1 1 2 2 2 0 Syntaxin XhlA PF10779.4 KFX99881.1 - 1.5 8.7 6.2 1.3 9.0 2.2 2.1 2 0 0 2 2 2 0 Haemolysin XhlA Mpv17_PMP22 PF04117.7 KFX99882.1 - 9.9e-16 57.1 0.1 2e-15 56.1 0.1 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Epimerase PF01370.16 KFX99883.1 - 8.3e-09 35.2 0.3 1.2e-07 31.4 0.2 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFX99883.1 - 3.3e-07 30.5 0.1 5.4e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFX99883.1 - 3.5e-07 29.7 0.0 5.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KFX99883.1 - 2.6e-06 26.3 0.1 4.6e-05 22.2 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KFX99883.1 - 0.0017 18.3 0.1 0.0032 17.4 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.12 KFX99883.1 - 0.011 16.1 0.1 0.034 14.5 0.1 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.7 KFX99883.1 - 0.011 14.7 0.8 0.034 13.0 0.1 1.8 1 1 1 2 2 2 0 Male sterility protein ApbA PF02558.11 KFX99883.1 - 0.013 14.9 0.1 0.025 14.0 0.1 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF4046 PF13255.1 KFX99883.1 - 0.048 12.3 0.0 0.07 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4046) Pyr_redox PF00070.22 KFX99883.1 - 0.051 13.9 0.2 0.1 13.0 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 KFX99883.1 - 0.053 13.3 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KFX99883.1 - 0.09 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.17 KFX99884.1 - 1.2e-65 221.9 0.0 1.3e-65 221.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HgmA PF04209.8 KFX99885.1 - 5.7e-182 604.8 0.0 6.5e-182 604.6 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Dabb PF07876.7 KFX99886.1 - 5e-11 42.8 0.1 5.7e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Matrix PF00661.16 KFX99886.1 - 0.11 10.7 0.1 4.3 5.5 0.0 2.0 2 0 0 2 2 2 0 Viral matrix protein ERCC4 PF02732.10 KFX99887.1 - 1.6e-24 86.2 0.0 3.4e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain CorA PF01544.13 KFX99890.1 - 8e-07 28.3 0.0 1.4e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Ribonuc_P_40 PF08584.6 KFX99901.1 - 2.6e-68 230.1 0.0 3.3e-68 229.7 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Ank_5 PF13857.1 KFX99902.1 - 9.1e-12 44.8 0.2 1.8e-09 37.5 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFX99902.1 - 5.6e-09 36.2 0.0 6.6e-07 29.6 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFX99902.1 - 1.4e-05 25.3 0.1 5.8e-05 23.3 0.1 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFX99902.1 - 0.0001 21.8 0.0 0.0014 18.3 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 KFX99902.1 - 0.00051 20.0 0.3 0.044 14.0 0.1 3.1 4 0 0 4 4 4 1 Ankyrin repeat Peptidase_M17_N PF02789.12 KFX99902.1 - 0.11 12.1 0.1 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain RNA_lig_T4_1 PF09511.5 KFX99903.1 - 4.1e-79 265.1 0.0 6.8e-79 264.4 0.0 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_CPD PF08302.6 KFX99903.1 - 2.3e-76 256.4 0.0 3.2e-76 255.9 0.0 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain tRNA_lig_kinase PF08303.6 KFX99903.1 - 2.4e-57 193.4 0.3 4.6e-57 192.5 0.2 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_17 PF13207.1 KFX99903.1 - 0.0076 17.0 0.1 0.053 14.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain CAP_GLY PF01302.20 KFX99904.1 - 4.5e-17 61.5 0.3 9.1e-17 60.5 0.2 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 KFX99904.1 - 1.3e-08 34.2 10.1 0.0018 17.8 0.3 4.8 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFX99904.1 - 6.1e-05 22.7 9.4 0.036 13.8 0.5 3.7 3 1 0 3 3 3 2 Leucine rich repeat zf-CCCH PF00642.19 KFX99904.1 - 0.0063 16.1 3.3 0.011 15.3 2.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRR_1 PF00560.28 KFX99904.1 - 0.0069 16.2 13.6 0.57 10.4 0.1 6.3 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.1 KFX99904.1 - 2.5 8.4 14.0 13 6.2 0.0 6.0 6 0 0 6 6 6 0 Leucine Rich repeat zf-met PF12874.2 KFX99905.1 - 1.9e-05 24.6 0.6 3.8e-05 23.7 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.6 KFX99905.1 - 0.052 12.8 0.9 0.095 11.9 0.6 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Pkinase PF00069.20 KFX99906.1 - 6.2e-57 192.6 0.1 8e-40 136.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFX99906.1 - 2.4e-26 92.3 0.1 9.9e-21 73.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFX99906.1 - 7.7e-05 21.7 0.0 0.00016 20.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFX99906.1 - 0.00014 21.6 3.0 0.0039 16.9 0.1 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 KFX99906.1 - 0.00055 19.0 0.0 0.0012 17.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 KFX99906.1 - 0.04 12.7 0.1 0.064 12.0 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 KFX99906.1 - 0.075 11.8 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 KFX99906.1 - 0.28 10.5 0.0 0.28 10.5 0.0 1.7 2 0 0 2 2 2 0 RIO1 family Tim54 PF11711.3 KFX99907.1 - 2.2e-125 418.2 0.0 3.5e-125 417.5 0.0 1.3 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 NARP1 PF12569.3 KFX99908.1 - 3.1e-200 666.3 31.1 9.2e-200 664.7 14.9 2.4 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 KFX99908.1 - 7.7e-22 76.7 38.5 3.5e-07 29.7 0.2 7.8 7 1 1 8 8 8 6 TPR repeat TPR_16 PF13432.1 KFX99908.1 - 1.7e-18 66.7 29.6 0.00016 22.2 1.0 8.5 5 3 4 9 9 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFX99908.1 - 1.3e-17 63.8 31.8 4e-05 23.8 2.3 7.5 8 1 1 9 9 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 KFX99908.1 - 3e-13 48.8 12.8 0.00023 21.1 0.0 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFX99908.1 - 3e-13 49.1 28.3 0.0011 19.4 0.0 10.9 8 3 5 13 13 10 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFX99908.1 - 3.9e-13 48.2 38.3 8.3e-05 22.2 0.1 10.7 11 1 0 11 11 10 4 Tetratricopeptide repeat TPR_1 PF00515.23 KFX99908.1 - 2.6e-11 42.6 30.8 1.9e-06 27.2 0.1 8.9 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 KFX99908.1 - 2.2e-10 40.2 6.9 0.00029 20.6 0.2 6.1 5 2 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KFX99908.1 - 2.8e-09 37.0 20.4 0.0045 17.0 0.4 6.0 4 3 1 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KFX99908.1 - 9.8e-09 35.0 34.2 0.0089 15.9 1.2 7.7 6 2 1 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 KFX99908.1 - 2.1e-07 30.2 25.3 0.00025 20.6 0.0 8.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFX99908.1 - 0.0013 18.3 17.6 1 9.3 0.0 7.0 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFX99908.1 - 0.008 16.5 32.2 1.5 9.4 0.1 9.6 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_3 PF07720.7 KFX99908.1 - 0.014 15.2 4.5 0.033 13.9 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Sel1 PF08238.7 KFX99908.1 - 0.034 14.7 6.1 2.1 9.1 0.3 4.1 3 0 0 3 3 3 0 Sel1 repeat TPR_4 PF07721.9 KFX99908.1 - 0.034 14.5 9.1 24 5.7 0.5 5.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KFX99908.1 - 0.066 13.1 12.2 7.3 6.5 0.1 4.9 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat NAM-associated PF14303.1 KFX99908.1 - 0.37 11.0 0.0 0.37 11.0 0.0 3.0 3 1 0 3 3 1 0 No apical meristem-associated C-terminal domain ESCRT-II PF05871.7 KFX99909.1 - 6.8e-51 171.8 0.3 9.9e-51 171.3 0.2 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit BRCT PF00533.21 KFX99910.1 - 6.5e-32 109.5 0.0 4.9e-09 36.2 0.0 6.5 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KFX99910.1 - 1.9e-29 101.2 0.2 4e-18 65.0 0.0 3.7 3 0 0 3 3 3 3 twin BRCT domain Ank_2 PF12796.2 KFX99937.1 - 4.9e-130 424.2 64.9 6.2e-19 68.1 0.1 10.6 1 1 10 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.25 KFX99937.1 - 1.1e-87 283.7 64.7 7.8e-07 28.6 0.1 20.9 21 0 0 21 21 20 18 Ankyrin repeat Ank_4 PF13637.1 KFX99937.1 - 5.4e-63 208.3 27.9 3.1e-08 33.8 0.0 17.1 5 4 13 19 19 19 14 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFX99937.1 - 1.1e-59 192.4 36.1 0.00028 20.8 0.0 20.0 20 0 0 20 20 19 14 Ankyrin repeat Ank_5 PF13857.1 KFX99937.1 - 1.2e-39 133.4 41.1 3.2e-06 27.2 0.1 15.4 8 4 8 16 16 16 11 Ankyrin repeats (many copies) NACHT PF05729.7 KFX99937.1 - 7.8e-11 41.9 0.0 2.5e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KFX99937.1 - 0.00069 19.7 0.0 0.0023 18.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFX99937.1 - 0.012 15.6 0.0 0.053 13.4 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain Cauli_DNA-bind PF03310.8 KFX99937.1 - 0.021 14.6 2.1 0.023 14.5 0.2 2.0 2 0 0 2 2 1 0 Caulimovirus DNA-binding protein AAA_19 PF13245.1 KFX99937.1 - 0.025 14.2 0.0 0.085 12.6 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 KFX99937.1 - 0.056 13.6 0.1 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.12 KFX99937.1 - 0.27 10.7 0.1 0.53 9.7 0.1 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein BicD PF09730.4 KFX99937.1 - 1.1 7.5 0.1 1.7 6.8 0.1 1.2 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D HdeA PF06411.6 KFX99938.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 HdeA/HdeB family Sugar_tr PF00083.19 KFX99939.1 - 3.3e-75 253.3 24.7 3.9e-75 253.1 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFX99939.1 - 5.7e-24 84.4 43.8 1.8e-20 72.9 14.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily YMF19 PF02326.10 KFX99939.1 - 0.024 15.1 1.3 1.3 9.6 0.0 2.7 2 0 0 2 2 2 0 Plant ATP synthase F0 Pam17 PF08566.5 KFX99939.1 - 0.066 12.9 0.2 0.16 11.6 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 Glyco_hydro_1 PF00232.13 KFX99940.1 - 4.1e-152 506.5 0.7 5.1e-152 506.2 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Fungal_trans PF04082.13 KFX99941.1 - 1.5e-15 56.8 0.3 3.6e-15 55.5 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFX99941.1 - 2.8e-11 43.1 4.8 4.9e-11 42.3 3.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.24 KFX99943.1 - 4.2e-17 62.5 0.0 1.2e-16 61.1 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFX99943.1 - 0.0023 17.9 0.2 0.025 14.5 0.2 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 KFX99943.1 - 0.0028 17.3 0.4 0.0069 16.1 0.3 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KFX99943.1 - 0.0081 16.3 0.9 0.031 14.4 0.1 2.3 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 KFX99943.1 - 0.017 14.8 0.0 0.042 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zot PF05707.7 KFX99943.1 - 0.035 13.5 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_17 PF13207.1 KFX99943.1 - 0.045 14.5 0.1 0.32 11.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KFX99943.1 - 0.073 13.0 0.1 0.22 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KFX99943.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Torsin PF06309.6 KFX99943.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Torsin Nepo_coat_N PF03689.10 KFX99944.1 - 0.17 11.6 0.1 0.42 10.3 0.0 1.6 2 0 0 2 2 2 0 Nepovirus coat protein, N-terminal domain RRM_1 PF00076.17 KFX99945.1 - 9.5e-13 47.5 1.2 0.00011 21.7 0.0 3.5 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFX99945.1 - 8.8e-12 44.8 0.1 0.00034 20.5 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.18 KFX99945.1 - 8.7e-10 38.2 2.1 8.7e-10 38.2 1.5 1.9 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 KFX99945.1 - 1e-06 28.4 0.7 3.6e-06 26.7 0.5 2.0 1 0 0 1 1 1 1 DExH-box splicing factor binding site zf-RanBP PF00641.13 KFX99945.1 - 0.00048 19.1 0.5 0.001 18.1 0.4 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RRM_5 PF13893.1 KFX99945.1 - 0.0054 16.5 0.0 0.091 12.6 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RED_N PF07808.8 KFX99945.1 - 0.011 14.9 0.7 0.031 13.5 0.5 1.7 1 0 0 1 1 1 0 RED-like protein N-terminal region MT0933_antitox PF14013.1 KFX99945.1 - 0.012 15.6 1.0 0.056 13.5 0.7 2.2 1 1 0 1 1 1 0 MT0933-like antitoxin protein zf-C2H2_jaz PF12171.3 KFX99945.1 - 2 8.6 5.4 0.16 12.1 0.3 1.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding P21-Arc PF04062.9 KFX99952.1 - 6.3e-65 218.1 0.0 1.2e-64 217.3 0.0 1.5 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Myb_DNA-bind_6 PF13921.1 KFX99952.1 - 0.039 14.0 1.7 4 7.6 0.2 3.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain DS PF01916.12 KFX99953.1 - 1.7e-146 487.0 0.0 2e-146 486.8 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 KFX99953.1 - 0.058 12.5 0.1 0.12 11.4 0.0 1.6 2 0 0 2 2 2 0 Carbamoyltransferase E1-E2_ATPase PF00122.15 KFX99954.1 - 7.1e-58 195.3 2.7 7.1e-58 195.3 1.9 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFX99954.1 - 1.1e-42 145.6 6.1 1.1e-42 145.6 4.3 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFX99954.1 - 5.7e-28 98.7 0.1 1.6e-27 97.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFX99954.1 - 1.2e-17 63.6 0.0 2.4e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFX99954.1 - 5.3e-16 59.3 0.0 2.1e-15 57.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFX99954.1 - 6.5e-10 38.3 2.8 1.4e-08 34.0 0.0 3.5 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KFX99954.1 - 0.0006 19.4 0.2 0.0068 16.0 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF21 PF01595.15 KFX99955.1 - 1.6e-29 102.4 2.1 2.6e-29 101.8 1.5 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KFX99955.1 - 9.6e-10 38.1 0.2 4.4e-08 32.7 0.1 2.9 3 0 0 3 3 3 1 CBS domain Cation_ATPase_C PF00689.16 KFX99956.1 - 5.8e-40 136.7 4.5 5.8e-40 136.7 3.1 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFX99956.1 - 5.5e-34 118.4 0.0 2e-21 77.4 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFX99956.1 - 2.5e-21 75.4 0.0 5.2e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 KFX99956.1 - 1.1e-19 70.3 6.3 1.1e-19 70.3 4.4 2.6 3 0 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 KFX99956.1 - 5.7e-14 52.7 0.0 3.1e-13 50.3 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFX99956.1 - 0.00032 20.3 0.3 0.00099 18.7 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase TFIIA_gamma_N PF02268.11 KFX99957.1 - 1.9e-24 85.0 0.0 2.6e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 KFX99957.1 - 2.2e-22 78.5 1.8 3.3e-22 78.0 1.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit PC4 PF02229.11 KFX99957.1 - 0.15 11.3 0.3 0.31 10.3 0.2 1.5 1 0 0 1 1 1 0 Transcriptional Coactivator p15 (PC4) ATP-synt_C PF00137.16 KFX99958.1 - 1e-28 99.0 24.8 4.1e-18 65.0 4.2 2.6 3 0 0 3 3 3 2 ATP synthase subunit C DUF3120 PF11318.3 KFX99958.1 - 0.016 15.4 0.2 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3120) Oxidored_q2 PF00420.19 KFX99958.1 - 4 7.1 7.2 2.4 7.8 1.6 2.9 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Cation_efflux PF01545.16 KFX99958.1 - 8.3 5.3 11.7 0.33 9.9 2.6 2.6 1 1 1 2 2 2 0 Cation efflux family LRR_9 PF14580.1 KFX99959.1 - 3e-51 173.4 0.2 5.3e-51 172.6 0.0 1.5 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 KFX99959.1 - 5.7e-12 44.9 5.3 2.7e-07 30.0 0.5 3.6 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFX99959.1 - 6.2e-12 45.0 0.7 9.9e-10 38.0 0.1 2.4 2 0 0 2 2 2 2 Leucine rich repeat LRR_6 PF13516.1 KFX99959.1 - 0.0026 17.6 0.6 8.5 6.7 0.1 4.2 4 1 0 4 4 4 1 Leucine Rich repeat LRR_7 PF13504.1 KFX99959.1 - 0.0052 16.7 1.7 14 6.4 0.1 4.6 4 0 0 4 4 4 1 Leucine rich repeat LRR_1 PF00560.28 KFX99959.1 - 0.025 14.5 1.8 11 6.4 0.1 4.5 4 1 1 5 5 5 0 Leucine Rich Repeat DUF4349 PF14257.1 KFX99959.1 - 0.12 11.6 1.1 0.19 10.9 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Pox_A_type_inc PF04508.7 KFX99959.1 - 6.3 6.8 6.3 6.7 6.7 0.3 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat AMP-binding PF00501.23 KFX99960.1 - 2.1e-27 95.5 0.0 6.5e-27 93.9 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme Pkinase PF00069.20 KFX99961.1 - 2.5e-23 82.5 0.0 5e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 KFX99961.1 - 1.2e-15 56.7 0.8 1.2e-07 31.3 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT PF02985.17 KFX99961.1 - 2.1e-11 42.9 5.6 0.0095 15.9 0.0 6.3 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.1 KFX99961.1 - 9.7e-08 32.1 5.0 0.066 13.5 0.2 3.9 3 1 0 3 3 3 3 HEAT repeats HEAT_EZ PF13513.1 KFX99961.1 - 6.4e-06 26.5 1.8 0.012 16.0 0.7 4.3 5 0 0 5 5 5 1 HEAT-like repeat Pkinase_Tyr PF07714.12 KFX99961.1 - 2.5e-05 23.4 0.0 4.1e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF2435 PF10363.4 KFX99961.1 - 0.0047 16.7 0.1 3 7.7 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF2435) Cnd1 PF12717.2 KFX99961.1 - 0.053 13.3 0.2 1.3 8.8 0.1 2.4 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Kinase-like PF14531.1 KFX99961.1 - 0.17 10.7 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Glyco_transf_90 PF05686.7 KFX99963.1 - 1.2e-14 53.8 3.7 1.8e-11 43.3 0.7 3.8 2 1 0 2 2 2 2 Glycosyl transferase family 90 Ribosomal_L18e PF00828.14 KFX99964.1 - 2.8e-12 47.1 0.7 5.9e-12 46.0 0.5 1.5 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 4HBT_3 PF13622.1 KFX99965.1 - 4.7e-32 111.7 0.1 5.6e-32 111.4 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KFX99965.1 - 8.6e-09 35.1 0.0 5.2e-05 22.8 0.0 2.7 2 1 0 2 2 2 2 Acyl-CoA thioesterase PX PF00787.19 KFX99966.1 - 9.4e-18 64.0 0.3 2.3e-17 62.8 0.2 1.6 1 0 0 1 1 1 1 PX domain SnoaL PF07366.7 KFX99966.1 - 8.5e-17 60.9 0.0 2.5e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KFX99966.1 - 2e-09 37.7 0.1 5.2e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 SnoaL-like domain Prefoldin_3 PF13758.1 KFX99966.1 - 1.5 8.6 7.1 0.1 12.4 0.3 2.2 2 0 0 2 2 2 0 Prefoldin subunit DYW_deaminase PF14432.1 KFX99967.1 - 1.6e-07 31.3 0.0 3.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 DYW family of nucleic acid deaminases Chromo PF00385.19 KFX99967.1 - 0.0026 17.3 4.8 0.41 10.3 0.3 2.8 1 1 1 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 KFX99967.1 - 0.26 11.1 4.4 0.88 9.5 0.3 2.4 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 Ribosomal_S19e PF01090.14 KFX99968.1 - 1.7e-56 189.5 0.2 1.9e-56 189.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Abhydrolase_6 PF12697.2 KFX99969.1 - 1.1e-25 90.9 0.1 2.3e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFX99969.1 - 2.6e-16 59.6 0.0 1.1e-15 57.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DSPc PF00782.15 KFX99969.1 - 1.3e-11 44.2 0.0 4e-11 42.6 0.0 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Abhydrolase_1 PF00561.15 KFX99969.1 - 9.9e-11 41.6 0.0 1.4e-09 37.8 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KFX99969.1 - 1.7e-06 28.4 0.0 4.8e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain PTPlike_phytase PF14566.1 KFX99969.1 - 3.2e-05 24.0 0.0 5.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate PGAP1 PF07819.8 KFX99969.1 - 4.6e-05 23.1 0.0 0.00024 20.7 0.0 2.0 1 1 0 1 1 1 1 PGAP1-like protein Y_phosphatase PF00102.22 KFX99969.1 - 0.0008 18.8 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Lipase_3 PF01764.20 KFX99969.1 - 0.0016 18.0 0.0 0.0034 17.0 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.15 KFX99969.1 - 0.0017 17.8 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative esterase LCAT PF02450.10 KFX99969.1 - 0.0045 16.0 0.0 0.0075 15.2 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Ser_hydrolase PF06821.8 KFX99969.1 - 0.053 13.1 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase DUF2305 PF10230.4 KFX99969.1 - 0.054 12.9 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_3 PF07859.8 KFX99969.1 - 0.055 13.0 0.0 0.099 12.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KFX99969.1 - 0.057 13.2 0.0 0.19 11.6 0.0 1.9 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_2 PF02230.11 KFX99969.1 - 0.067 12.6 0.0 3.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.13 KFX99969.1 - 0.069 12.4 0.0 2.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF900 PF05990.7 KFX99969.1 - 0.085 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) VirJ PF06057.6 KFX99969.1 - 0.092 12.5 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF676 PF05057.9 KFX99969.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) UQ_con PF00179.21 KFX99970.1 - 1.1e-21 76.7 0.0 1.9e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme B-block_TFIIIC PF04182.7 KFX99972.1 - 2.5e-13 49.6 0.0 6e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.2 KFX99972.1 - 0.0069 16.0 0.0 0.033 13.8 0.0 2.2 2 0 0 2 2 2 1 MarR family RNA_pol_Rpc34 PF05158.7 KFX99972.1 - 0.062 12.4 0.0 0.25 10.5 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase Rpc34 subunit Hanta_G1 PF01567.11 KFX99972.1 - 4.1 5.5 0.1 6.3 4.9 0.0 1.1 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 WD40 PF00400.27 KFX99973.1 - 1.7e-24 84.7 9.2 1.2e-10 40.7 0.1 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KFX99973.1 - 3e-18 65.4 0.0 8.5e-18 64.0 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nucleoporin_N PF08801.6 KFX99973.1 - 0.021 13.5 0.2 0.81 8.3 0.4 2.5 1 1 1 2 2 2 0 Nup133 N terminal like Adenylsucc_synt PF00709.16 KFX99977.1 - 2.1e-159 530.7 0.1 2.4e-159 530.5 0.1 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Mak10 PF04112.8 KFX99989.1 - 7e-48 162.0 0.1 1.2e-47 161.3 0.1 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_Eps PF04627.8 KFX99990.1 - 9.1e-22 76.3 3.0 4.1e-21 74.2 2.1 2.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Peptidase_M16 PF00675.15 KFX99990.1 - 5.2e-17 61.9 0.5 1.3e-16 60.6 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KFX99990.1 - 6.1e-15 55.3 0.0 1.3e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.8 KFX99991.1 - 3.2e-49 167.7 0.3 3.7e-46 157.7 0.0 3.1 2 1 1 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 KFX99991.1 - 3.6e-18 65.2 2.4 1.6e-15 56.7 0.2 3.6 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 KFX99991.1 - 2.3e-11 43.1 0.6 1.5e-06 27.6 0.1 2.8 2 0 0 2 2 2 2 TFIIE alpha subunit TrmB PF01978.14 KFX99991.1 - 0.00063 19.3 0.0 4.3 7.1 0.0 3.7 3 0 0 3 3 3 2 Sugar-specific transcriptional regulator TrmB Mito_carr PF00153.22 KFX99992.1 - 2.8e-28 97.4 1.2 5.2e-14 51.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2665 PF11654.3 KFX99993.1 - 4e-06 26.2 0.1 7.9e-06 25.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2665) Acyl-CoA_dh_1 PF00441.19 KFY00015.1 - 2.1e-32 112.3 0.9 3.1e-32 111.7 0.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFY00015.1 - 2.7e-20 71.6 0.3 4.8e-20 70.8 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KFY00015.1 - 5.7e-13 49.4 0.2 8.1e-12 45.7 0.0 2.6 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KFY00015.1 - 1.4e-05 25.3 0.1 3.4e-05 24.0 0.1 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Ras PF00071.17 KFY00016.1 - 1.5e-28 99.2 0.0 2.7e-28 98.3 0.0 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KFY00016.1 - 6.6e-08 33.0 0.0 9.5e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 KFY00016.1 - 0.016 14.4 0.0 0.85 8.8 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B MMR_HSR1 PF01926.18 KFY00016.1 - 0.14 12.1 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase PBP PF01161.15 KFY00022.1 - 2.7e-11 43.5 0.0 4.4e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein CTDII PF01556.13 KFY00024.1 - 1.6e-26 91.9 1.1 2.7e-21 75.2 0.1 3.4 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 KFY00024.1 - 1.5e-22 79.0 1.7 2.8e-22 78.2 1.2 1.5 1 0 0 1 1 1 1 DnaJ domain SAP30_Sin3_bdg PF13867.1 KFY00024.1 - 1.5e-12 47.1 0.1 1.8e-11 43.7 0.1 2.3 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DnaJ_CXXCXGXG PF00684.14 KFY00024.1 - 1.2e-10 41.2 19.9 2.8e-10 40.1 13.8 1.6 1 0 0 1 1 1 1 DnaJ central domain DAO PF01266.19 KFY00049.1 - 2.1e-09 36.7 0.0 2.2e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFY00049.1 - 2.2e-05 24.3 0.0 4.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFY00049.1 - 0.00044 19.4 0.1 0.00057 19.0 0.1 1.1 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KFY00049.1 - 0.00044 19.2 0.0 0.00044 19.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KFY00049.1 - 0.0025 17.7 0.0 0.0027 17.6 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFY00049.1 - 0.0066 16.8 0.1 0.0098 16.2 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFY00049.1 - 0.009 15.0 0.1 0.011 14.8 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KFY00049.1 - 0.028 14.4 0.0 0.032 14.3 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KFY00049.1 - 0.052 12.1 0.1 0.062 11.9 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KFY00049.1 - 0.092 12.5 0.1 0.14 11.8 0.0 1.3 1 1 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KFY00049.1 - 0.094 11.6 0.0 0.094 11.6 0.0 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein GMC_oxred_N PF00732.14 KFY00049.1 - 0.096 11.8 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 GMC oxidoreductase NAD_binding_7 PF13241.1 KFY00049.1 - 0.14 12.4 0.0 0.14 12.4 0.0 1.1 1 0 0 1 1 1 0 Putative NAD(P)-binding OTU PF02338.14 KFY00050.1 - 1.3e-14 54.8 0.0 2.8e-14 53.7 0.0 1.6 1 1 0 1 1 1 1 OTU-like cysteine protease CUE PF02845.11 KFY00050.1 - 0.00046 19.6 0.1 0.00088 18.7 0.0 1.4 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.1 KFY00050.1 - 0.0016 17.9 0.0 0.0031 17.0 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Peptidase_C65 PF10275.4 KFY00050.1 - 0.14 11.4 0.0 1 8.6 0.0 2.1 2 0 0 2 2 2 0 Peptidase C65 Otubain Thioredoxin PF00085.15 KFY00051.1 - 3.6e-29 100.4 0.2 4.3e-29 100.2 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KFY00051.1 - 3.5e-07 30.4 0.2 5.4e-06 26.5 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFY00051.1 - 4.5e-06 26.6 0.0 4.7e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 KFY00051.1 - 0.0002 21.0 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 KFY00051.1 - 0.00025 20.6 0.0 0.00031 20.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 KFY00051.1 - 0.0028 17.1 0.1 0.024 14.1 0.1 1.9 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.1 KFY00051.1 - 0.014 15.4 0.1 0.024 14.6 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like Phosducin PF02114.11 KFY00051.1 - 0.014 14.1 0.0 0.017 13.8 0.0 1.0 1 0 0 1 1 1 0 Phosducin Glutaredoxin PF00462.19 KFY00051.1 - 0.017 15.0 0.4 0.25 11.3 0.1 2.2 1 1 1 2 2 2 0 Glutaredoxin Thioredox_DsbH PF03190.10 KFY00051.1 - 0.035 13.8 0.1 0.046 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Noggin PF05806.7 KFY00055.1 - 0.31 10.3 2.6 0.42 9.8 1.8 1.1 1 0 0 1 1 1 0 Noggin Mannosyl_trans2 PF04188.8 KFY00057.1 - 3.5e-66 223.9 3.4 4.4e-66 223.6 2.3 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) LMBR1 PF04791.11 KFY00058.1 - 0.53 8.8 3.2 0.84 8.1 1.5 1.6 1 1 0 1 1 1 0 LMBR1-like membrane protein Colipase_C PF02740.9 KFY00061.1 - 0.003 17.2 0.5 0.003 17.2 0.4 2.4 3 0 0 3 3 3 1 Colipase, C-terminal domain Prokineticin PF06607.6 KFY00061.1 - 0.025 14.6 5.8 0.032 14.3 4.0 1.1 1 0 0 1 1 1 0 Prokineticin NACHT PF05729.7 KFY00062.1 - 2.2e-10 40.4 0.2 8.7e-10 38.4 0.1 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KFY00062.1 - 5.6e-08 32.9 0.1 1.7e-07 31.3 0.1 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KFY00062.1 - 6.5e-08 32.5 0.1 2.1e-06 27.6 0.0 3.0 2 1 0 2 2 2 1 AAA domain Ank_2 PF12796.2 KFY00062.1 - 1.6e-05 25.1 0.0 0.00022 21.4 0.0 2.7 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) NB-ARC PF00931.17 KFY00062.1 - 0.00013 20.8 0.0 0.00034 19.5 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain Ank PF00023.25 KFY00062.1 - 0.00018 21.1 0.0 0.012 15.3 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat AAA_22 PF13401.1 KFY00062.1 - 0.0008 19.5 0.0 0.0023 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Ank_5 PF13857.1 KFY00062.1 - 0.0037 17.4 0.1 0.089 13.0 0.0 3.4 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Arch_ATPase PF01637.13 KFY00062.1 - 0.0094 15.6 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase DAP3 PF10236.4 KFY00062.1 - 0.013 14.4 0.1 0.027 13.4 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Ank_3 PF13606.1 KFY00062.1 - 0.023 14.8 0.0 1.8 9.0 0.0 3.6 3 0 0 3 3 2 0 Ankyrin repeat AAA_29 PF13555.1 KFY00062.1 - 0.057 12.9 0.6 0.14 11.6 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ank_4 PF13637.1 KFY00062.1 - 0.063 13.8 0.0 1.3 9.6 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeats (many copies) AAA_25 PF13481.1 KFY00062.1 - 0.087 12.2 0.1 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KFY00062.1 - 0.12 11.9 0.1 0.36 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.9 KFY00062.1 - 0.12 11.2 0.0 15 4.4 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase DUF258 PF03193.11 KFY00062.1 - 0.16 11.1 0.2 0.31 10.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Cupin_2 PF07883.6 KFY00064.1 - 0.0004 19.8 0.0 0.0021 17.5 0.0 2.1 1 1 0 1 1 1 1 Cupin domain Rep_fac-A_3 PF08661.6 KFY00065.1 - 1.6e-23 82.6 0.0 1.9e-23 82.4 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 FAM194 PF14977.1 KFY00065.1 - 0.039 12.9 0.0 0.045 12.7 0.0 1.1 1 0 0 1 1 1 0 FAM194 protein DUF2470 PF10615.4 KFY00065.1 - 0.15 12.3 0.3 0.21 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2470) tRNA-synt_2 PF00152.15 KFY00066.1 - 1.1e-89 300.6 0.5 1.7e-89 299.9 0.4 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KFY00066.1 - 1.4e-09 37.6 0.0 3.3e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KFY00066.1 - 9.5e-07 28.2 0.2 0.0021 17.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) NARP1 PF12569.3 KFY00066.1 - 2.3 6.8 10.4 3.5 6.2 7.2 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 COX15-CtaA PF02628.10 KFY00067.1 - 3.2e-21 75.4 0.2 4.1e-21 75.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein NMO PF03060.10 KFY00073.1 - 2.5e-13 49.9 0.0 2.6e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KFY00073.1 - 0.00022 20.2 0.0 0.00022 20.2 0.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain TPP_enzyme_N PF02776.13 KFY00074.1 - 3.7e-32 111.1 0.1 6e-32 110.4 0.1 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KFY00074.1 - 4.2e-17 62.1 0.0 8e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KFY00074.1 - 9.5e-13 47.9 0.1 3e-12 46.3 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Amidohydro_2 PF04909.9 KFY00075.1 - 2.2e-42 145.4 0.6 2.8e-42 145.1 0.4 1.2 1 0 0 1 1 1 1 Amidohydrolase AMP-binding PF00501.23 KFY00076.1 - 5.3e-88 295.2 0.0 7.7e-88 294.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFY00076.1 - 2.8e-12 47.3 0.0 6.1e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.13 KFY00076.1 - 9.1e-07 28.0 0.1 1.1e-05 24.4 0.0 2.2 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY00076.1 - 4e-05 23.4 9.1 6.7e-05 22.7 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med15 PF09606.5 KFY00076.1 - 0.18 10.0 3.4 0.25 9.4 2.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal ketoacyl-synt PF00109.21 KFY00078.1 - 6.5e-72 242.0 0.2 2.4e-71 240.1 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KFY00078.1 - 1.6e-57 194.1 2.8 2.3e-57 193.6 0.1 2.7 3 0 0 3 3 3 1 KR domain Acyl_transf_1 PF00698.16 KFY00078.1 - 4.2e-55 187.3 0.0 7.8e-55 186.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KFY00078.1 - 2.1e-48 165.0 0.0 1.1e-47 162.6 0.0 2.1 1 1 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KFY00078.1 - 6.3e-45 153.0 0.8 4.8e-43 146.9 0.0 2.8 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KFY00078.1 - 8.5e-38 128.8 0.5 3.1e-37 127.0 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KFY00078.1 - 3.4e-06 27.2 0.0 1.1e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.21 KFY00078.1 - 0.00026 20.5 0.1 0.0011 18.4 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.15 KFY00078.1 - 0.02 14.7 1.1 7.7 6.4 0.1 2.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ACP_syn_III PF08545.5 KFY00078.1 - 0.028 14.0 0.8 0.33 10.6 0.0 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 KFY00078.1 - 0.044 12.7 0.0 0.11 11.4 0.0 1.6 1 0 0 1 1 1 0 Thiolase, N-terminal domain YflT PF11181.3 KFY00078.1 - 0.086 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Heat induced stress protein YflT DUF915 PF06028.6 KFY00078.1 - 0.24 10.4 0.0 0.5 9.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Zn_clus PF00172.13 KFY00079.1 - 2.4e-07 30.5 9.4 2.4e-07 30.5 6.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1284 PF06935.6 KFY00080.1 - 0.057 13.5 0.1 0.09 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1284) EthD PF07110.6 KFY00081.1 - 7e-17 62.1 0.7 8.5e-17 61.8 0.5 1.1 1 0 0 1 1 1 1 EthD domain p450 PF00067.17 KFY00082.1 - 1.8e-52 178.4 0.0 2.4e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 KFY00083.1 - 1.8e-09 37.1 0.0 3.3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFY00083.1 - 5.6e-09 35.7 0.1 1e-08 34.9 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_8 PF13450.1 KFY00084.1 - 2.5e-11 43.4 0.6 5.7e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KFY00084.1 - 1.7e-08 33.9 0.5 3.1e-08 33.1 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFY00084.1 - 1.4e-05 24.1 1.5 2.2e-05 23.5 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KFY00084.1 - 1.5e-05 25.3 0.1 3.3e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFY00084.1 - 2.7e-05 22.8 0.7 4.2e-05 22.2 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.19 KFY00084.1 - 6.6e-05 21.9 1.4 0.00017 20.6 0.9 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFY00084.1 - 0.00018 21.6 0.1 0.00033 20.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFY00084.1 - 0.0002 21.3 0.3 0.00036 20.4 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFY00084.1 - 0.0021 16.9 0.2 0.003 16.4 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.19 KFY00084.1 - 0.0031 16.6 0.0 0.0058 15.7 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 KFY00084.1 - 0.014 14.4 0.1 0.022 13.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 KFY00084.1 - 0.029 13.8 0.9 0.06 12.7 0.4 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 KFY00085.1 - 3.7e-18 65.7 6.8 6.3e-12 45.2 1.5 2.9 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KFY00085.1 - 4.4e-07 29.1 0.8 2.6e-06 26.6 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFY00085.1 - 0.00028 20.8 0.8 0.0008 19.3 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFY00085.1 - 0.0048 15.7 1.4 0.029 13.2 0.2 2.5 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 KFY00085.1 - 0.0073 16.2 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFY00085.1 - 0.014 15.7 0.6 0.032 14.6 0.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFY00085.1 - 0.061 12.2 0.6 2.3 7.0 0.1 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KFY00085.1 - 0.13 12.3 0.3 0.54 10.2 0.2 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 KFY00085.1 - 0.2 11.0 0.5 0.41 10.0 0.3 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Transferase PF02458.10 KFY00086.1 - 2.3e-29 102.1 0.0 8.3e-29 100.2 0.0 1.6 2 0 0 2 2 2 1 Transferase family FSH1 PF03959.8 KFY00087.1 - 9e-28 97.1 0.0 1.2e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KFY00087.1 - 0.00022 20.9 0.1 0.00035 20.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFY00087.1 - 0.0008 19.3 3.5 0.002 18.0 2.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFY00087.1 - 0.0013 18.2 0.4 0.018 14.5 0.1 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase ketoacyl-synt PF00109.21 KFY00088.1 - 1.1e-72 244.6 0.2 2.2e-72 243.6 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KFY00088.1 - 9e-31 107.3 0.2 2.5e-29 102.6 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KFY00088.1 - 2.2e-29 101.7 0.1 5.6e-29 100.4 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 KFY00088.1 - 9.3e-28 96.7 0.0 2e-27 95.7 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 KFY00088.1 - 5e-14 52.5 0.0 2e-13 50.6 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY00088.1 - 3.6e-11 42.8 0.0 8.1e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 KFY00088.1 - 2.8e-09 37.0 0.9 7.7e-09 35.6 0.7 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 KFY00088.1 - 3e-09 37.2 0.0 9.6e-09 35.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFY00088.1 - 1.9e-08 34.1 0.0 8.6e-08 32.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY00088.1 - 2.7e-07 31.1 0.0 1.1e-06 29.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 KFY00088.1 - 5.5e-07 29.2 0.0 1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.18 KFY00088.1 - 7.8e-06 25.0 0.0 1.9e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 KFY00088.1 - 0.00018 20.9 0.0 0.00042 19.7 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 KFY00088.1 - 0.00025 20.2 0.0 0.00073 18.7 0.0 1.7 2 0 0 2 2 1 1 ubiE/COQ5 methyltransferase family adh_short PF00106.20 KFY00088.1 - 0.00045 20.1 0.0 0.001 19.0 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NodS PF05401.6 KFY00088.1 - 0.00045 19.6 0.0 0.00093 18.6 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_25 PF13649.1 KFY00088.1 - 0.00047 20.4 0.0 0.0025 18.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain KR PF08659.5 KFY00088.1 - 0.00049 19.8 0.0 0.0014 18.3 0.0 1.7 1 0 0 1 1 1 1 KR domain Methyltransf_26 PF13659.1 KFY00088.1 - 0.00059 19.8 0.0 0.0019 18.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.10 KFY00088.1 - 0.0015 17.4 0.0 0.0084 15.0 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RrnaAD PF00398.15 KFY00088.1 - 0.002 17.1 0.0 0.0037 16.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase RmlD_sub_bind PF04321.12 KFY00088.1 - 0.0049 15.7 0.0 0.53 9.1 0.0 2.4 2 0 0 2 2 2 1 RmlD substrate binding domain Methyltransf_28 PF02636.12 KFY00088.1 - 0.0051 16.2 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF3886 PF13025.1 KFY00089.1 - 0.045 13.7 5.2 0.067 13.1 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) adh_short PF00106.20 KFY00090.1 - 8.3e-21 74.6 0.0 1.3e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFY00090.1 - 3.9e-10 39.9 0.0 5.4e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFY00090.1 - 0.00025 20.7 0.0 0.00057 19.5 0.0 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFY00090.1 - 0.0036 17.3 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KFY00090.1 - 0.042 12.7 0.0 0.057 12.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Histone PF00125.19 KFY00107.1 - 1.6e-08 34.5 0.0 0.0033 17.4 0.0 2.2 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 YXWGXW PF12779.2 KFY00107.1 - 0.15 11.9 3.5 9.2 6.2 0.2 2.3 2 0 0 2 2 2 0 YXWGXW repeat (2 copies) FMN_dh PF01070.13 KFY00110.1 - 3e-124 414.4 0.0 3.8e-124 414.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 KFY00110.1 - 8.5e-05 21.8 2.5 0.00014 21.1 1.7 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 KFY00110.1 - 0.0001 21.4 0.3 0.11 11.5 0.2 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 KFY00110.1 - 0.0002 20.3 2.6 0.00093 18.1 0.9 2.3 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KFY00110.1 - 0.00039 19.4 0.3 0.00063 18.7 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 KFY00110.1 - 0.0015 17.8 0.3 0.065 12.4 0.0 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.16 KFY00110.1 - 0.073 12.1 0.2 0.23 10.4 0.1 1.7 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase Methyltransf_23 PF13489.1 KFY00111.1 - 3.7e-10 39.7 0.0 6.3e-10 39.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY00111.1 - 2.4e-08 34.5 0.0 3.9e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY00111.1 - 4.2e-07 30.3 0.0 7.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY00111.1 - 7.8e-07 28.7 0.0 1.2e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY00111.1 - 1.6e-06 28.4 0.0 5.8e-06 26.7 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY00111.1 - 0.00011 22.5 0.0 0.00033 20.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFY00111.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KFY00111.1 - 0.02 14.0 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family EI24 PF07264.6 KFY00112.1 - 6.1e-07 29.0 8.4 1.2e-06 28.1 5.8 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Picorna_P3A PF06363.6 KFY00112.1 - 0.14 12.1 0.8 3.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Picornaviridae P3A protein zf-RING_2 PF13639.1 KFY00113.1 - 2e-13 49.9 5.7 3.9e-13 49.0 3.9 1.5 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KFY00113.1 - 2.9e-10 39.7 0.0 8e-10 38.3 0.0 1.8 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 KFY00113.1 - 7.2e-09 35.5 5.3 1.3e-08 34.7 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFY00113.1 - 1.5e-08 34.1 2.7 2.6e-08 33.3 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFY00113.1 - 4.2e-08 33.1 2.9 4.2e-08 33.1 2.0 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KFY00113.1 - 1.5e-07 30.9 3.1 2.4e-07 30.3 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFY00113.1 - 5.3e-07 29.2 2.2 8.8e-07 28.5 1.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Glyco_tranf_2_4 PF13704.1 KFY00113.1 - 2.7e-06 27.6 1.2 6.3e-06 26.4 0.9 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.22 KFY00113.1 - 3.7e-06 26.4 0.8 1.5e-05 24.4 0.6 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 92 RRP14 PF15459.1 KFY00113.1 - 0.0011 18.9 1.0 0.0044 17.0 0.7 2.0 1 0 0 1 1 1 1 60S ribosome biogenesis protein Rrp14 zf-Apc11 PF12861.2 KFY00113.1 - 0.0033 17.2 0.8 0.0033 17.2 0.6 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KFY00113.1 - 0.07 13.0 3.3 0.2 11.5 2.4 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFY00113.1 - 0.13 11.9 2.3 0.37 10.5 1.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 KFY00113.1 - 0.14 12.1 1.5 0.38 10.7 1.0 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 KFY00113.1 - 0.2 11.7 3.3 0.38 10.8 2.3 1.5 1 0 0 1 1 1 0 RING-variant domain ODV-E18 PF10717.4 KFY00113.1 - 0.22 11.0 1.1 0.56 9.6 0.0 2.3 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 zf-RING-like PF08746.6 KFY00113.1 - 0.33 11.0 3.5 0.61 10.1 2.4 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.1 KFY00113.1 - 0.51 9.9 2.4 0.99 9.0 1.7 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ACPS PF01648.15 KFY00114.1 - 1e-07 31.7 0.1 6.7e-07 29.1 0.0 2.3 2 2 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Glyco_hydro_61 PF03443.9 KFY00115.1 - 1.6e-51 175.2 0.0 1.8e-51 175.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4360 PF14273.1 KFY00116.1 - 1.2e-54 184.7 3.4 5.6e-54 182.5 2.4 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4360) NmrA PF05368.8 KFY00117.1 - 3.8e-30 104.8 0.0 4.7e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFY00117.1 - 1.9e-14 54.1 0.0 2.5e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFY00117.1 - 0.011 15.2 0.0 0.87 8.9 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFY00117.1 - 0.078 11.8 0.0 1.7 7.5 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein Alpha-amylase PF00128.19 KFY00118.1 - 4.2e-62 210.3 0.0 5.6e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KFY00118.1 - 1.7e-16 60.0 0.1 5.1e-16 58.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) MFS_1 PF07690.11 KFY00118.1 - 8.3e-13 47.7 46.8 3.8e-12 45.5 31.9 2.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KFY00118.1 - 0.0022 16.3 21.5 0.42 8.7 14.9 2.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF187 PF02638.10 KFY00118.1 - 0.12 11.1 0.0 0.21 10.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 DUF1428 PF07237.6 KFY00118.1 - 0.13 12.2 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) hDGE_amylase PF14701.1 KFY00118.1 - 0.23 10.3 0.0 0.35 9.7 0.0 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Pyr_redox_2 PF07992.9 KFY00119.1 - 6.7e-10 39.1 0.0 1.2e-09 38.3 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFY00119.1 - 2.2e-09 37.6 1.1 3.8e-08 33.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFY00119.1 - 1.1e-08 35.3 0.0 0.038 14.0 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFY00119.1 - 0.0077 16.0 2.0 11 5.7 0.0 3.9 3 1 1 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KFY00119.1 - 0.015 14.1 0.2 0.18 10.7 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KFY00119.1 - 0.1 11.4 2.5 10 4.8 0.0 3.3 4 0 0 4 4 4 0 FAD dependent oxidoreductase TraA PF05513.6 KFY00119.1 - 0.14 12.3 0.1 0.31 11.2 0.0 1.6 1 1 0 1 1 1 0 TraA Acetyltransf_3 PF13302.1 KFY00123.1 - 1.7e-05 25.0 0.0 3.7e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain F-box PF00646.28 KFY00123.1 - 0.081 12.5 0.1 0.27 10.9 0.1 1.8 1 0 0 1 1 1 0 F-box domain Peptidase_S8 PF00082.17 KFY00126.1 - 9.8e-39 133.1 20.8 1.3e-38 132.7 14.4 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KFY00126.1 - 2.4e-08 34.4 0.1 4.4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Hid1 PF12722.2 KFY00127.1 - 8.3 3.9 9.5 8.6 3.8 6.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Chitin_bind_3 PF03067.10 KFY00129.1 - 0.024 14.9 0.0 0.078 13.2 0.0 1.8 1 1 0 1 1 1 0 Chitin binding domain Glyco_hydro_18 PF00704.23 KFY00130.1 - 4e-94 315.8 4.2 4.7e-94 315.6 2.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Peptidase_M16_C PF05193.16 KFY00130.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase M16 inactive domain PhyH PF05721.8 KFY00131.1 - 1e-05 25.6 0.3 9.2e-05 22.5 0.2 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Imm15 PF15590.1 KFY00131.1 - 0.074 12.1 0.1 1.1 8.4 0.0 2.5 2 0 0 2 2 2 0 Immunity protein 15 Fungal_trans_2 PF11951.3 KFY00132.1 - 3.1e-19 68.8 4.2 2.6e-17 62.5 0.8 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY00132.1 - 0.0056 16.5 1.7 0.012 15.5 1.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 KFY00133.1 - 1.1e-76 258.2 24.4 1.4e-76 257.9 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY00133.1 - 2.6e-30 105.3 23.8 2.6e-30 105.3 16.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFY00133.1 - 2.7e-05 22.5 0.7 2.7e-05 22.5 0.5 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) FUSC-like PF12805.2 KFY00133.1 - 2.4 6.9 8.2 4.6 6.0 5.7 1.4 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Abhydrolase_2 PF02230.11 KFY00134.1 - 2.2e-10 40.3 0.4 6.4e-07 29.0 0.0 2.1 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KFY00134.1 - 5.2e-06 26.2 0.0 6.7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFY00134.1 - 0.053 13.3 0.0 0.067 13.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family GFO_IDH_MocA PF01408.17 KFY00135.1 - 1.8e-15 57.5 0.1 3e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KFY00135.1 - 2.8e-08 33.5 0.0 4.4e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Glyco_hydro_2_N PF02837.13 KFY00136.1 - 7.9e-08 32.0 0.0 1.9e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KFY00136.1 - 1.2e-06 28.9 0.1 2.8e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 KFY00136.1 - 0.051 12.4 0.1 0.097 11.5 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Band_7_1 PF13421.1 KFY00136.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family TPPK_C PF12555.3 KFY00137.1 - 5.7 6.7 6.8 8.8 6.1 4.7 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal UQ_con PF00179.21 KFY00144.1 - 1.4e-46 157.3 0.1 2.8e-46 156.4 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFY00144.1 - 0.00069 19.3 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KFY00144.1 - 0.0076 15.9 0.1 0.014 15.0 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 KFY00144.1 - 0.033 14.0 0.6 0.049 13.5 0.4 1.4 1 1 0 1 1 1 0 RWD domain Methyltransf_24 PF13578.1 KFY00145.1 - 2.4e-12 47.6 0.0 1.3e-11 45.2 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain WD40 PF00400.27 KFY00145.1 - 3e-11 42.7 15.9 3.7e-05 23.4 0.2 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Methyltransf_3 PF01596.12 KFY00145.1 - 8.9e-06 24.8 0.1 2.5e-05 23.4 0.1 1.7 1 1 0 1 1 1 1 O-methyltransferase zf-RING_2 PF13639.1 KFY00145.1 - 0.025 14.3 8.7 0.055 13.3 6.0 1.6 1 0 0 1 1 1 0 Ring finger domain GFA PF04828.9 KFY00146.1 - 1.2e-11 44.3 0.2 3.2e-11 43.0 0.2 1.7 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme HET PF06985.6 KFY00146.1 - 2.9e-11 43.6 0.0 2.4e-10 40.6 0.0 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 KFY00147.1 - 1.1e-28 100.2 0.0 1.3e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFY00147.1 - 3.5e-26 92.4 0.0 4.5e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFY00147.1 - 4.4e-11 42.7 0.0 6.3e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KFY00147.1 - 4.1e-05 23.2 0.2 0.00016 21.3 0.1 2.0 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KFY00147.1 - 0.00018 21.0 0.0 0.00026 20.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KFY00147.1 - 0.0066 15.6 0.0 0.0096 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 2-Hacid_dh_C PF02826.14 KFY00147.1 - 0.019 14.1 0.2 0.76 8.9 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KFY00147.1 - 0.031 13.3 0.0 0.064 12.3 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 KFY00147.1 - 0.051 13.8 1.5 0.13 12.5 1.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding Polysacc_synt_2 PF02719.10 KFY00147.1 - 0.079 11.8 0.2 0.094 11.6 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KFY00147.1 - 0.082 12.9 0.0 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding PBP_like_2 PF12849.2 KFY00148.1 - 1.9e-09 37.4 0.2 2.3e-09 37.1 0.1 1.1 1 0 0 1 1 1 1 PBP superfamily domain CBM_1 PF00734.13 KFY00149.1 - 3.8e-09 36.0 11.0 7.9e-09 35.0 7.6 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF605 PF04652.11 KFY00149.1 - 4.8 6.4 20.2 6.8 5.9 14.0 1.1 1 0 0 1 1 1 0 Vta1 like RTA1 PF04479.8 KFY00150.1 - 1.3e-11 44.4 12.3 4.9e-11 42.5 8.5 1.8 1 1 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.13 KFY00151.1 - 7.1e-09 35.4 5.1 1.6e-08 34.3 3.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFY00151.1 - 0.034 12.7 1.4 0.055 12.0 1.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Flavoprotein PF02441.14 KFY00152.1 - 9.4e-38 128.8 0.2 1.3e-37 128.3 0.2 1.2 1 0 0 1 1 1 1 Flavoprotein Glyco_hydro_45 PF02015.11 KFY00153.1 - 4.6e-62 209.6 16.3 5.6e-62 209.3 11.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Fasciclin PF02469.17 KFY00155.1 - 1.6e-38 131.5 0.0 2.8e-20 72.6 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Kp4 PF09044.5 KFY00156.1 - 1.5e-17 63.6 4.8 1.9e-17 63.2 3.3 1.1 1 0 0 1 1 1 1 Kp4 MU117 PF15474.1 KFY00156.1 - 0.0046 17.4 1.4 0.0063 16.9 1.0 1.2 1 0 0 1 1 1 1 Meiotically up-regulated gene family Ank_2 PF12796.2 KFY00157.1 - 1.5e-58 195.1 6.9 8e-13 48.5 0.0 8.0 1 1 7 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 KFY00157.1 - 2.6e-47 156.3 17.7 6.1e-06 25.7 0.3 12.9 14 0 0 14 14 14 11 Ankyrin repeat Ank_3 PF13606.1 KFY00157.1 - 3.9e-43 141.1 10.6 0.0071 16.4 0.0 12.6 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.1 KFY00157.1 - 2.9e-40 135.9 12.2 4.7e-09 36.5 0.0 9.7 5 1 6 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY00157.1 - 5.7e-40 134.4 16.6 4.9e-06 26.6 0.1 12.2 6 3 5 12 12 12 8 Ankyrin repeats (many copies) CorA PF01544.13 KFY00157.1 - 4.9e-07 29.0 0.0 1.3e-06 27.6 0.0 1.8 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MFS_1 PF07690.11 KFY00161.1 - 1.5e-12 46.8 8.6 2e-12 46.5 6.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MnhB PF04039.8 KFY00162.1 - 0.48 10.4 3.6 0.26 11.3 0.4 2.2 2 1 1 3 3 3 0 Domain related to MnhB subunit of Na+/H+ antiporter Glyco_hydro_76 PF03663.9 KFY00163.1 - 3.2e-154 513.7 15.5 4.2e-154 513.3 10.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Synaptobrevin PF00957.16 KFY00164.1 - 2.9e-27 94.1 0.4 3.5e-27 93.8 0.3 1.0 1 0 0 1 1 1 1 Synaptobrevin GP41 PF00517.12 KFY00164.1 - 0.0026 17.3 0.1 0.0038 16.7 0.1 1.3 1 0 0 1 1 1 1 Retroviral envelope protein Sec20 PF03908.8 KFY00164.1 - 0.18 11.5 2.3 0.49 10.1 1.6 1.6 1 1 0 1 1 1 0 Sec20 Fzo_mitofusin PF04799.8 KFY00164.1 - 2.4 7.4 7.4 0.36 10.1 0.4 2.0 1 1 1 2 2 2 0 fzo-like conserved region DUF619 PF04768.8 KFY00165.1 - 1.4e-50 171.0 0.5 2.6e-50 170.1 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 KFY00165.1 - 9.7e-30 103.3 0.0 2.5e-29 102.0 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 KFY00165.1 - 1.4e-25 90.2 0.0 2.5e-25 89.4 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 KFY00165.1 - 0.034 14.0 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus YjbR PF04237.8 KFY00165.1 - 0.037 14.3 0.2 3.5 8.0 0.0 3.2 3 0 0 3 3 3 0 YjbR Metallophos PF00149.23 KFY00166.1 - 3.9e-08 32.9 1.4 7.1e-08 32.0 1.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RRM_6 PF14259.1 KFY00166.1 - 0.00086 19.2 0.0 0.0026 17.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) 5_nucleotid_C PF02872.13 KFY00166.1 - 0.0089 16.0 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain RRM_1 PF00076.17 KFY00166.1 - 0.017 14.7 0.0 0.041 13.5 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1687 PF07955.6 KFY00167.1 - 2.8e-16 59.7 0.3 1.9e-15 57.0 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) NAC PF01849.13 KFY00168.1 - 8.7e-20 70.0 0.2 1.6e-19 69.1 0.2 1.5 1 0 0 1 1 1 1 NAC domain Nup35_RRM PF05172.8 KFY00168.1 - 0.0052 16.5 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Gly-rich_Ago1 PF12764.2 KFY00168.1 - 4.9 7.8 10.8 0.26 11.9 2.5 2.6 2 0 0 2 2 2 0 Glycine-rich region of argonaut AdoMet_MTase PF07757.8 KFY00169.1 - 7.5e-40 135.5 0.0 1.2e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 KFY00169.1 - 0.0064 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KFY00169.1 - 0.015 14.9 0.0 0.066 12.8 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KFY00169.1 - 0.078 13.5 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L24e PF01246.15 KFY00170.1 - 7.3e-30 102.6 0.7 7.3e-30 102.6 0.5 1.8 2 1 0 2 2 2 1 Ribosomal protein L24e WTX PF09422.5 KFY00170.1 - 0.064 12.2 5.3 0.072 12.0 3.7 1.0 1 0 0 1 1 1 0 WTX protein Tom37_C PF11801.3 KFY00170.1 - 3.4 7.4 4.8 3.7 7.3 2.9 1.3 1 1 0 1 1 1 0 Tom37 C-terminal domain CBP4 PF07960.6 KFY00171.1 - 2e-36 124.4 0.7 2.3e-36 124.2 0.5 1.0 1 0 0 1 1 1 1 CBP4 Trp_oprn_chp PF09534.5 KFY00171.1 - 0.013 15.1 0.0 0.027 14.0 0.0 1.5 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Seryl_tRNA_N PF02403.17 KFY00171.1 - 0.032 14.2 5.3 0.049 13.6 3.7 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF2852 PF11014.3 KFY00171.1 - 1.7 8.6 5.5 0.93 9.4 1.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) Sel1 PF08238.7 KFY00172.1 - 1.9e-34 117.2 26.2 7.1e-06 26.4 0.2 7.9 7 0 0 7 7 7 6 Sel1 repeat TPR_6 PF13174.1 KFY00172.1 - 0.83 10.2 11.1 1 9.9 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Hce2 PF14856.1 KFY00173.1 - 3.1e-16 59.0 0.0 4.2e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor CRCB PF02537.10 KFY00174.1 - 1.9e-29 101.9 22.8 3.4e-19 68.8 6.2 3.6 3 1 0 3 3 3 3 CrcB-like protein MFS_1 PF07690.11 KFY00175.1 - 9.4e-30 103.5 67.5 1.5e-15 56.7 23.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFY00175.1 - 0.0064 14.9 36.4 0.034 12.5 13.1 3.0 1 1 1 2 2 2 2 MFS/sugar transport protein Amidase PF01425.16 KFY00176.1 - 3.6e-92 309.5 0.0 4.3e-92 309.2 0.0 1.1 1 0 0 1 1 1 1 Amidase AMP-binding PF00501.23 KFY00177.1 - 3.7e-167 555.9 2.8 4.3e-74 249.3 0.0 3.4 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KFY00177.1 - 7.3e-111 369.8 0.0 1.9e-37 128.7 0.0 5.0 4 1 0 4 4 4 3 Condensation domain PP-binding PF00550.20 KFY00177.1 - 4.6e-20 71.6 0.1 4e-10 39.8 0.2 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 KFY00177.1 - 0.018 15.3 0.9 0.51 10.6 0.0 3.1 3 0 0 3 3 3 0 HxxPF-repeated domain ABC_tran PF00005.22 KFY00178.1 - 3.1e-49 166.7 0.0 3.9e-29 101.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KFY00178.1 - 1.1e-30 107.0 20.1 5.1e-24 85.1 5.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KFY00178.1 - 1.1e-14 55.1 4.1 0.00025 21.1 0.0 4.3 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 KFY00178.1 - 2.9e-11 43.0 0.8 0.017 14.3 0.0 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KFY00178.1 - 4.9e-10 39.6 0.5 0.0008 19.4 0.0 3.6 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 KFY00178.1 - 1.9e-08 33.6 0.1 0.011 15.2 0.0 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KFY00178.1 - 1.2e-07 31.1 0.0 0.002 17.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KFY00178.1 - 1.2e-07 31.9 1.0 0.039 14.1 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KFY00178.1 - 1e-06 29.2 0.1 0.0064 16.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KFY00178.1 - 1.1e-06 28.2 0.2 0.014 14.8 0.0 2.5 2 1 0 2 2 2 2 AAA-like domain T2SE PF00437.15 KFY00178.1 - 2.2e-06 26.7 0.1 0.045 12.6 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein Zeta_toxin PF06414.7 KFY00178.1 - 1.1e-05 24.7 0.1 0.13 11.3 0.0 2.9 2 1 1 3 3 3 2 Zeta toxin FtsK_SpoIIIE PF01580.13 KFY00178.1 - 2.8e-05 23.6 0.0 0.022 14.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 KFY00178.1 - 6.1e-05 23.8 0.0 0.3 11.9 0.0 3.1 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KFY00178.1 - 8.7e-05 22.4 0.1 0.2 11.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 KFY00178.1 - 9.5e-05 22.8 0.0 0.061 13.8 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_25 PF13481.1 KFY00178.1 - 9.7e-05 21.8 0.1 0.2 11.0 0.0 3.1 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 KFY00178.1 - 0.00011 21.9 0.0 0.082 12.5 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase DUF87 PF01935.12 KFY00178.1 - 0.00012 22.0 1.7 0.026 14.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_24 PF13479.1 KFY00178.1 - 0.00031 20.3 0.0 0.38 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KFY00178.1 - 0.0008 19.7 0.0 0.52 10.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 KFY00178.1 - 0.00082 19.2 0.5 0.38 10.5 0.1 2.7 3 0 0 3 3 2 1 Dynamin family AAA PF00004.24 KFY00178.1 - 0.00084 19.5 0.1 4.9 7.3 0.0 3.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KFY00178.1 - 0.00085 19.2 0.0 0.59 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KFY00178.1 - 0.0016 17.9 1.5 0.22 10.9 0.2 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KFY00178.1 - 0.0019 17.8 0.4 0.44 10.2 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KFY00178.1 - 0.0047 16.5 0.8 8.4 6.0 0.0 3.8 3 0 0 3 3 3 0 NACHT domain RNA_helicase PF00910.17 KFY00178.1 - 0.0086 16.2 0.0 6.6 6.9 0.0 2.9 3 0 0 3 3 2 0 RNA helicase AAA_14 PF13173.1 KFY00178.1 - 0.014 15.2 0.1 2 8.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.13 KFY00178.1 - 0.014 14.8 0.1 8.3 5.8 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase SbcCD_C PF13558.1 KFY00178.1 - 0.018 14.9 0.1 1.8 8.5 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Adeno_IVa2 PF02456.10 KFY00178.1 - 0.022 13.4 0.0 3.4 6.2 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_30 PF13604.1 KFY00178.1 - 0.024 14.2 0.2 24 4.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.17 KFY00178.1 - 0.03 13.1 0.0 6.4 5.5 0.0 2.4 2 1 0 2 2 2 0 NB-ARC domain DUF815 PF05673.8 KFY00178.1 - 0.031 13.2 0.0 1.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ArgK PF03308.11 KFY00178.1 - 0.073 11.8 0.0 1.3 7.7 0.0 2.2 2 0 0 2 2 2 0 ArgK protein TrwB_AAD_bind PF10412.4 KFY00178.1 - 0.074 11.6 0.0 6.5 5.2 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.9 KFY00178.1 - 0.1 12.2 1.7 25 4.5 0.2 3.5 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 KFY00178.1 - 0.17 11.3 0.0 4.4 6.7 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ATP_bind_1 PF03029.12 KFY00178.1 - 0.17 11.3 0.2 11 5.4 0.0 2.6 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.9 KFY00178.1 - 0.21 10.5 0.5 8.8 5.2 0.0 2.9 3 1 0 3 3 3 0 KAP family P-loop domain NTPase_1 PF03266.10 KFY00178.1 - 0.64 9.7 3.0 13 5.4 0.0 3.2 4 0 0 4 4 3 0 NTPase AAA_15 PF13175.1 KFY00178.1 - 0.81 8.6 0.1 33 3.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Zn_clus PF00172.13 KFY00179.1 - 9.7e-07 28.6 11.7 9.7e-07 28.6 8.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 KFY00179.1 - 0.0041 17.3 1.2 0.018 15.3 0.9 2.2 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFY00179.1 - 0.087 12.9 0.0 0.27 11.4 0.0 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding adh_short PF00106.20 KFY00180.1 - 1.7e-25 89.8 1.1 2.4e-25 89.4 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFY00180.1 - 5e-15 55.6 0.4 7.3e-15 55.0 0.3 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFY00180.1 - 7.8e-10 38.9 0.0 1.1e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFY00180.1 - 3.8e-07 29.8 0.1 5.7e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFY00180.1 - 7.7e-06 25.0 0.1 9.4e-06 24.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KFY00180.1 - 0.016 14.0 0.1 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 KFY00180.1 - 0.078 12.7 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Fungal_trans PF04082.13 KFY00181.1 - 1.3e-18 66.8 0.5 2.6e-18 65.8 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY00181.1 - 2e-07 30.7 8.3 3.8e-07 29.8 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KFY00182.1 - 1.5e-18 67.2 0.1 1.7e-17 63.8 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFY00182.1 - 1.8e-09 37.7 0.1 6.4e-06 26.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFY00182.1 - 3.3e-08 33.4 0.0 4.9e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFY00182.1 - 0.00011 22.2 0.3 0.00047 20.2 0.2 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFY00182.1 - 0.00023 20.6 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family CDC48_N PF02359.13 KFY00182.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain 3Beta_HSD PF01073.14 KFY00182.1 - 0.12 11.0 0.1 0.22 10.2 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MIT PF04212.13 KFY00183.1 - 9.6e-18 63.8 4.9 2.7e-17 62.4 3.4 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain FAD-oxidase_C PF02913.14 KFY00183.1 - 1.6e-16 60.3 0.0 3.2e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KFY00183.1 - 1.9e-15 56.5 0.0 5.7e-15 55.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Abhydrolase_2 PF02230.11 KFY00184.1 - 3.2e-56 190.1 0.0 4.6e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase LigB PF02900.13 KFY00184.1 - 1.8e-19 69.7 0.1 3e-13 49.3 0.0 2.7 3 0 0 3 3 3 2 Catalytic LigB subunit of aromatic ring-opening dioxygenase Abhydrolase_5 PF12695.2 KFY00184.1 - 2.8e-09 36.8 0.0 7.4e-09 35.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family EFG_C PF00679.19 KFY00184.1 - 3.9e-07 29.8 0.0 1.2e-06 28.2 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G C-terminus Abhydrolase_6 PF12697.2 KFY00184.1 - 4.7e-05 23.3 0.2 0.0032 17.4 0.1 2.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFY00184.1 - 5e-05 22.6 0.4 0.009 15.2 0.0 2.4 1 1 1 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.13 KFY00184.1 - 7.1e-05 22.1 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.8 KFY00184.1 - 0.0002 20.8 0.0 0.00045 19.7 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) EFG_IV PF03764.13 KFY00184.1 - 0.026 14.0 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Elongation factor G, domain IV Abhydrolase_3 PF07859.8 KFY00184.1 - 0.035 13.6 0.0 3.9 6.9 0.0 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 KFY00184.1 - 0.11 12.1 0.0 0.31 10.6 0.0 1.8 1 0 0 1 1 1 0 Lipase (class 3) adh_short PF00106.20 KFY00191.1 - 0.0095 15.8 0.0 0.03 14.2 0.0 1.9 2 1 0 2 2 2 1 short chain dehydrogenase Imm_superinfect PF14373.1 KFY00191.1 - 0.012 15.2 1.2 0.037 13.6 0.8 1.9 1 0 0 1 1 1 0 Superinfection immunity protein TMF_DNA_bd PF12329.3 KFY00191.1 - 0.022 14.5 0.4 0.037 13.8 0.3 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Acetyltransf_8 PF13523.1 KFY00192.1 - 2.4e-45 154.1 0.1 4e-45 153.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KFY00192.1 - 9.4e-05 22.6 0.0 0.00017 21.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3279 PF11682.3 KFY00192.1 - 0.12 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3279) NAD_binding_10 PF13460.1 KFY00194.1 - 3.1e-07 30.5 0.0 4.3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFY00194.1 - 5.3e-05 22.0 0.0 6.4e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 KFY00194.1 - 0.00092 19.1 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 KFY00194.1 - 0.004 17.4 0.0 0.013 15.8 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 KFY00194.1 - 0.013 15.0 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFY00194.1 - 0.033 13.1 0.0 0.15 10.9 0.0 2.0 1 1 0 1 1 1 0 Male sterility protein DXP_reductoisom PF02670.11 KFY00194.1 - 0.05 14.1 0.0 0.076 13.5 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Melibiase PF02065.13 KFY00195.1 - 4e-07 29.0 0.0 0.0014 17.4 0.0 2.2 2 0 0 2 2 2 2 Melibiase HAMP PF00672.20 KFY00196.1 - 0.0018 18.3 0.2 2 8.6 0.0 3.1 1 1 1 2 2 2 2 HAMP domain HypD PF01924.11 KFY00196.1 - 0.015 14.0 3.2 5 5.7 0.1 3.6 2 1 2 4 4 4 0 Hydrogenase formation hypA family zf-ZPR1 PF03367.8 KFY00196.1 - 0.062 12.4 12.2 22 4.1 0.1 5.9 6 0 0 6 6 6 0 ZPR1 zinc-finger domain DUF2669 PF10876.3 KFY00196.1 - 0.15 11.7 0.6 10 5.7 0.0 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2669) Plasmid_stab_B PF10784.4 KFY00196.1 - 3.8 7.2 6.8 39 3.9 0.1 3.5 3 0 0 3 3 3 0 Plasmid stability protein APH PF01636.18 KFY00197.1 - 1.1e-14 54.8 0.0 1.6e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KFY00197.1 - 0.095 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain EcKinase PF02958.15 KFY00197.1 - 0.14 11.2 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase O-FucT PF10250.4 KFY00211.1 - 0.00032 19.9 0.0 0.27 10.2 0.0 2.1 1 1 1 2 2 2 2 GDP-fucose protein O-fucosyltransferase VSP PF03302.8 KFY00212.1 - 0.02 13.5 0.0 0.028 13.0 0.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF4366 PF14283.1 KFY00212.1 - 0.049 13.0 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) SNF2_N PF00176.18 KFY00213.1 - 3.7e-69 232.8 0.5 7.4e-69 231.8 0.1 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFY00213.1 - 6.2e-17 61.2 0.0 1.7e-16 59.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFY00213.1 - 1.3e-05 25.1 0.0 1.3e-05 25.1 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KFY00213.1 - 0.044 13.9 0.0 0.16 12.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain Mit_KHE1 PF10173.4 KFY00214.1 - 1.2e-61 207.7 0.8 1.5e-61 207.5 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related Pterin_bind PF00809.17 KFY00216.1 - 9.2e-62 208.1 0.0 1.4e-61 207.4 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 KFY00216.1 - 7.5e-40 135.5 0.0 1.4e-39 134.6 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.10 KFY00217.1 - 2.7e-72 243.7 1.5 3.2e-72 243.4 1.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KFY00217.1 - 3.7e-10 39.2 0.0 1.3e-08 34.1 0.0 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KFY00217.1 - 1.2e-07 30.9 1.9 2.1e-07 30.1 1.3 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 KFY00217.1 - 2.2e-05 23.5 0.3 3.3e-05 22.9 0.2 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.12 KFY00217.1 - 0.0021 17.0 0.2 0.0039 16.1 0.1 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase FAD_binding_4 PF01565.18 KFY00218.1 - 2.8e-23 81.9 3.3 4.9e-23 81.1 2.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFY00218.1 - 0.0012 18.7 0.0 0.003 17.4 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF566 PF04484.7 KFY00219.1 - 1.2 8.5 6.1 1.2 8.5 4.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Cupin_8 PF13621.1 KFY00220.1 - 4.1e-33 114.9 0.0 6.1e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KFY00220.1 - 2.8e-07 30.1 0.0 1.6e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Cupin superfamily protein Ribul_P_3_epim PF00834.14 KFY00220.1 - 0.00059 18.9 0.0 0.00096 18.3 0.0 1.2 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family JmjC PF02373.17 KFY00220.1 - 0.0092 16.2 0.0 0.032 14.4 0.0 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase WD40 PF00400.27 KFY00232.1 - 7.9e-15 54.0 6.7 1.8e-06 27.6 0.5 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.3 KFY00232.1 - 0.0049 15.0 0.1 0.0073 14.4 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Cyclin_N PF00134.18 KFY00232.1 - 0.069 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain Baculo_LEF-3 PF05847.6 KFY00232.1 - 0.18 10.6 0.6 0.28 10.0 0.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus late expression factor 3 (LEF-3) FYVE PF01363.16 KFY00233.1 - 0.0014 18.4 0.6 0.0016 18.2 0.4 1.2 1 0 0 1 1 1 1 FYVE zinc finger Prok-RING_1 PF14446.1 KFY00233.1 - 0.0094 15.6 5.9 0.014 15.1 4.1 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-RING_4 PF14570.1 KFY00233.1 - 0.016 14.7 5.3 0.025 14.1 3.7 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_2 PF14445.1 KFY00233.1 - 0.038 13.9 2.2 0.061 13.2 1.5 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 FYVE_2 PF02318.11 KFY00233.1 - 0.063 13.1 2.2 0.098 12.5 1.5 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger zf-B_box PF00643.19 KFY00233.1 - 0.5 10.3 8.1 1.2 9.0 5.6 1.6 1 1 0 1 1 1 0 B-box zinc finger IBR PF01485.16 KFY00233.1 - 0.68 9.8 6.3 2.6 7.9 4.4 1.9 1 1 0 1 1 1 0 IBR domain DNA_RNApol_7kD PF03604.8 KFY00233.1 - 1.6 8.2 7.9 5.7 6.4 5.5 1.9 1 1 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit ZZ PF00569.12 KFY00233.1 - 9.4 5.8 9.5 24 4.5 0.9 2.2 1 1 1 2 2 2 0 Zinc finger, ZZ type APH PF01636.18 KFY00234.1 - 5.9e-08 32.7 0.0 1.2e-07 31.7 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFY00234.1 - 0.0015 18.1 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase ThiF PF00899.16 KFY00234.1 - 0.13 12.0 0.1 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 ThiF family DUF3049 PF11250.3 KFY00234.1 - 0.14 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3049) Podoplanin PF05808.6 KFY00235.1 - 0.066 12.7 0.1 0.08 12.4 0.1 1.3 1 0 0 1 1 1 0 Podoplanin DUF367 PF04034.8 KFY00236.1 - 2.1e-46 156.6 0.0 2.9e-46 156.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 KFY00236.1 - 6.4e-12 44.8 0.6 1.3e-11 43.8 0.4 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Neisseria_TspB PF05616.8 KFY00236.1 - 0.073 11.4 2.8 0.52 8.6 1.2 2.1 2 0 0 2 2 2 0 Neisseria meningitidis TspB protein VHS PF00790.14 KFY00237.1 - 3e-45 153.2 0.0 1.2e-44 151.3 0.0 2.0 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 KFY00237.1 - 1.4e-24 85.9 0.5 3.5e-24 84.6 0.3 1.7 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 KFY00237.1 - 4.9e-19 68.7 0.1 1.1e-18 67.5 0.1 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain DUF2360 PF10152.4 KFY00237.1 - 2.4 8.4 8.5 10 6.4 4.7 2.9 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) GTP_EFTU PF00009.22 KFY00239.1 - 3.2e-38 131.0 2.3 3.2e-38 131.0 1.6 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KFY00239.1 - 1e-23 83.2 0.5 3.6e-23 81.5 0.2 2.1 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KFY00239.1 - 1.7e-12 47.2 2.0 1.1e-05 25.4 0.0 3.3 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFY00239.1 - 4.3e-07 29.8 0.1 1e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.10 KFY00239.1 - 1.5e-05 24.5 0.0 3.6e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Miro PF08477.8 KFY00239.1 - 2.1e-05 24.9 0.0 5.9e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 KFY00239.1 - 0.00069 19.1 0.3 0.0024 17.3 0.2 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 KFY00239.1 - 0.00099 18.3 0.5 0.002 17.4 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family ArgK PF03308.11 KFY00239.1 - 0.0037 16.0 1.1 0.14 10.9 0.4 2.5 2 0 0 2 2 2 1 ArgK protein SRPRB PF09439.5 KFY00239.1 - 0.0082 15.3 0.0 0.022 13.9 0.0 1.8 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KFY00239.1 - 0.01 15.1 0.2 0.039 13.2 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.18 KFY00239.1 - 0.7 9.6 3.8 21 4.8 0.1 3.6 3 1 1 4 4 4 0 Dynamin family zf-RING_3 PF14369.1 KFY00240.1 - 1.2 9.2 7.4 1.3 9.0 0.7 2.4 2 0 0 2 2 2 0 zinc-finger OrfB_Zn_ribbon PF07282.6 KFY00240.1 - 2.3 7.9 4.9 10 5.8 3.1 2.2 1 1 0 1 1 1 0 Putative transposase DNA-binding domain ASF1_hist_chap PF04729.8 KFY00241.1 - 2.7e-62 208.9 0.0 4e-62 208.4 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone CReP_N PF10472.4 KFY00241.1 - 0.098 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 eIF2-alpha phosphatase phosphorylation constitutive repressor Ras PF00071.17 KFY00245.1 - 3.6e-36 123.9 0.0 2e-22 79.2 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KFY00245.1 - 9.2e-10 39.0 0.0 2.5e-09 37.6 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 KFY00245.1 - 0.00022 21.1 0.0 0.00043 20.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 KFY00245.1 - 0.0014 17.9 0.0 0.0056 15.9 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFY00245.1 - 0.027 13.9 1.8 0.49 9.7 0.1 3.2 2 2 1 3 3 3 0 Elongation factor Tu GTP binding domain AAA_25 PF13481.1 KFY00245.1 - 0.14 11.4 0.0 0.14 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Lipase_GDSL_2 PF13472.1 KFY00246.1 - 1.3e-20 74.3 0.1 1.5e-20 74.0 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFY00246.1 - 1.1e-16 61.3 0.0 1.4e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase KH_1 PF00013.24 KFY00247.1 - 2.9e-18 65.2 2.9 5.8e-08 32.2 0.2 6.2 6 0 0 6 6 6 4 KH domain KH_3 PF13014.1 KFY00247.1 - 7e-16 57.4 4.8 0.00013 21.5 0.7 4.9 5 0 0 5 5 5 4 KH domain SUR7 PF06687.7 KFY00248.1 - 1.1e-31 110.0 1.8 1.2e-31 109.9 1.2 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 KFY00248.1 - 0.0062 16.4 1.7 0.0094 15.8 1.2 1.3 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 DUF4013 PF13197.1 KFY00248.1 - 0.013 14.7 7.7 0.021 14.1 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) O-antigen_lig PF13425.1 KFY00248.1 - 0.05 13.5 4.1 0.092 12.7 2.8 1.4 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4282 PF14110.1 KFY00248.1 - 6.4 7.0 10.3 12 6.1 7.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) F-box PF00646.28 KFY00249.1 - 0.0068 16.0 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain eIF3g PF12353.3 KFY00251.1 - 1e-46 158.0 6.7 1.7e-46 157.3 4.7 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 KFY00251.1 - 4.6e-17 61.4 0.1 7.7e-17 60.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY00251.1 - 5.8e-12 45.4 0.1 1e-11 44.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFY00251.1 - 1e-05 25.2 0.1 1.7e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSP70 PF00012.15 KFY00252.1 - 6.4e-263 873.1 15.2 7.3e-263 872.9 10.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFY00252.1 - 7.7e-15 54.3 4.7 1.3e-12 47.0 1.0 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 KFY00252.1 - 0.00014 21.4 0.1 0.00039 20.1 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 KFY00252.1 - 0.0012 18.6 6.2 1.9 8.3 0.5 4.3 2 2 0 2 2 2 2 Cell division protein FtsA Hydantoinase_A PF01968.13 KFY00252.1 - 0.0092 15.1 1.5 1.2 8.2 0.0 3.3 2 1 0 3 3 3 1 Hydantoinase/oxoprolinase StbA PF06406.6 KFY00252.1 - 0.035 13.0 4.4 0.12 11.2 0.0 2.8 3 1 1 4 4 4 0 StbA protein DUF615 PF04751.9 KFY00252.1 - 0.12 12.0 4.4 0.1 12.2 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF615) DnaG_DnaB_bind PF08278.6 KFY00252.1 - 0.12 12.5 2.6 0.43 10.7 1.8 1.9 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding DUF4363 PF14276.1 KFY00252.1 - 0.14 11.9 3.3 0.25 11.0 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) DUF2415 PF10313.4 KFY00253.1 - 5.1e-13 48.4 0.0 9.7e-13 47.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) zf-BED PF02892.10 KFY00254.1 - 0.0017 18.0 0.2 0.0017 18.0 0.1 2.3 2 0 0 2 2 2 1 BED zinc finger Zn_clus PF00172.13 KFY00254.1 - 0.02 14.7 8.2 0.045 13.6 5.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_6 PF13912.1 KFY00254.1 - 0.11 12.4 0.4 0.27 11.2 0.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger HSP70 PF00012.15 KFY00255.1 - 3.4e-168 560.3 2.9 3.4e-168 560.3 2.0 1.5 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KFY00255.1 - 1.8e-12 46.4 0.1 1.1e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 KFY00255.1 - 0.00012 21.9 1.1 0.18 11.6 0.1 3.8 3 1 0 3 3 3 2 Cell division protein FtsA Cu-oxidase_3 PF07732.10 KFY00256.1 - 3.9e-45 152.3 12.4 3.8e-42 142.7 0.1 4.4 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFY00256.1 - 1.8e-37 127.9 15.7 4.7e-35 120.0 5.3 4.1 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KFY00256.1 - 1.4e-32 112.7 0.3 7.5e-30 103.9 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase MFS_1 PF07690.11 KFY00257.1 - 7.4e-45 153.1 47.9 1.7e-44 151.9 33.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KFY00257.1 - 2.9e-10 39.0 21.1 4.7e-10 38.3 14.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4184 PF13803.1 KFY00257.1 - 0.12 11.6 6.0 0.051 12.8 0.9 2.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4184) DNA_ligase_A_C PF04679.10 KFY00257.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region PEP_mutase PF13714.1 KFY00258.1 - 2.4e-41 141.4 0.3 3e-41 141.2 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KFY00258.1 - 3.8e-18 65.0 0.2 5.4e-18 64.4 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family AflR PF08493.5 KFY00259.1 - 1e-07 31.2 0.2 1.2e-07 31.0 0.2 1.2 1 0 0 1 1 1 1 Aflatoxin regulatory protein Myb_DNA-bind_6 PF13921.1 KFY00260.1 - 9.7e-27 92.8 7.2 3.2e-13 49.5 0.3 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KFY00260.1 - 1.7e-22 79.1 12.9 4.1e-10 39.5 0.7 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 KFY00260.1 - 0.013 15.3 3.7 0.084 12.7 1.2 2.6 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 KFY00260.1 - 0.082 12.7 1.2 0.7 9.7 0.0 2.8 2 1 1 3 3 3 0 Rap1 Myb domain MADF_DNA_bdg PF10545.4 KFY00260.1 - 0.27 11.4 7.3 1.6 8.9 2.7 3.1 2 1 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Beta-lactamase PF00144.19 KFY00261.1 - 1.6e-43 149.0 0.0 2.1e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Phage_Treg PF04761.7 KFY00261.1 - 0.062 13.0 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator Peptidase_S11 PF00768.15 KFY00261.1 - 0.13 11.4 0.0 1.5 7.9 0.0 2.4 2 1 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase FAD_binding_3 PF01494.14 KFY00262.1 - 3e-14 52.8 0.0 3.2e-06 26.4 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 KFY00262.1 - 3.1e-05 23.9 0.0 7.3e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFY00262.1 - 0.0016 18.3 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFY00262.1 - 0.0041 16.0 0.0 0.0056 15.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 KFY00262.1 - 0.0054 15.6 0.0 0.21 10.4 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.19 KFY00262.1 - 0.013 14.3 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFY00262.1 - 0.024 15.0 0.0 0.064 13.6 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KFY00262.1 - 0.091 12.7 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Lycopene_cycl PF05834.7 KFY00262.1 - 0.092 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein A2M_N_2 PF07703.9 KFY00262.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Alpha-2-macroglobulin family N-terminal region EthD PF07110.6 KFY00263.1 - 1e-13 52.0 0.3 1.3e-13 51.6 0.2 1.2 1 0 0 1 1 1 1 EthD domain MMS1_N PF10433.4 KFY00264.1 - 2.6e-66 223.8 0.0 2.8e-53 180.7 0.0 2.3 1 1 1 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term GTP_EFTU PF00009.22 KFY00264.1 - 3.6e-31 108.0 0.0 1.1e-30 106.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KFY00264.1 - 1.6e-17 63.3 0.0 4e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KFY00264.1 - 1.5e-08 34.6 2.5 8.1e-07 29.0 0.1 2.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFY00264.1 - 1.7e-05 24.7 0.0 4.3e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KFY00264.1 - 0.013 15.0 0.0 0.033 13.7 0.0 1.7 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RabGAP-TBC PF00566.13 KFY00265.1 - 8.5e-25 87.4 0.0 1.4e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain M60-like PF13402.1 KFY00265.1 - 0.041 12.7 0.1 0.073 11.9 0.0 1.5 2 0 0 2 2 2 0 Peptidase M60-like family Prefoldin_2 PF01920.15 KFY00265.1 - 0.16 11.7 2.4 0.53 10.0 0.0 2.2 2 0 0 2 2 2 0 Prefoldin subunit O-FucT PF10250.4 KFY00267.1 - 0.0021 17.2 0.0 0.05 12.7 0.0 2.2 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF3274 PF11678.3 KFY00268.1 - 0.0048 16.1 0.6 0.011 15.0 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3274) TPR_10 PF13374.1 KFY00268.1 - 0.13 12.2 3.1 1.4 8.9 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_30 PF02055.11 KFY00269.1 - 7.1e-15 54.1 1.1 4.2e-09 35.1 0.1 2.2 2 0 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 KFY00269.1 - 4.6e-12 45.5 1.9 1e-09 37.8 0.0 2.7 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 CBM_1 PF00734.13 KFY00269.1 - 0.12 12.0 14.9 0.37 10.5 10.3 1.9 1 0 0 1 1 1 0 Fungal cellulose binding domain adh_short PF00106.20 KFY00274.1 - 1.9e-19 70.2 0.0 2.9e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFY00274.1 - 4.2e-08 33.2 0.0 1.3e-07 31.6 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFY00274.1 - 0.00033 20.1 0.0 0.00066 19.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KFY00274.1 - 0.00071 19.2 0.1 0.0017 18.0 0.0 1.5 1 1 0 1 1 1 1 KR domain MFS_1 PF07690.11 KFY00275.1 - 1.4e-32 112.7 27.3 2.1e-32 112.2 18.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3425 PF11905.3 KFY00275.1 - 1.1e-30 106.3 1.7 2.1e-30 105.4 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DUF3824 PF12868.2 KFY00275.1 - 0.4 11.5 4.0 0.13 13.1 0.3 1.9 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Fic PF02661.13 KFY00276.1 - 4.7e-06 27.2 0.0 0.00012 22.6 0.0 2.5 2 1 0 2 2 2 1 Fic/DOC family tRNA-synt_1g PF09334.6 KFY00277.1 - 6.5e-117 390.4 0.0 9.3e-117 389.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KFY00277.1 - 3.1e-24 84.9 3.3 6e-10 37.7 0.0 4.0 1 1 3 4 4 4 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 KFY00277.1 - 1.1e-06 28.0 0.0 0.00037 19.7 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Cu_amine_oxid PF01179.15 KFY00281.1 - 2.1e-142 474.7 0.0 2.5e-142 474.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KFY00281.1 - 8.5e-19 67.4 0.0 1.8e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KFY00281.1 - 6.6e-15 54.9 0.1 1.3e-14 53.9 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain AA_permease_2 PF13520.1 KFY00282.1 - 3.2e-54 184.1 51.3 4e-54 183.7 35.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFY00282.1 - 4.1e-22 78.1 39.3 5.6e-22 77.7 27.2 1.1 1 0 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.19 KFY00287.1 - 6e-88 295.3 20.3 7.6e-88 295.0 14.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY00287.1 - 4.2e-12 45.4 40.4 5.3e-10 38.5 21.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily LVIVD PF08309.6 KFY00288.1 - 1.7e-12 46.1 1.6 0.088 11.8 0.0 5.3 5 0 0 5 5 5 4 LVIVD repeat Beta_propel PF09826.4 KFY00288.1 - 0.048 12.0 0.2 6.6 4.9 0.0 2.5 1 1 1 2 2 2 0 Beta propeller domain Abhydrolase_2 PF02230.11 KFY00289.1 - 7.8e-35 120.2 0.1 2.6e-24 85.8 0.0 4.1 4 0 0 4 4 4 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KFY00289.1 - 5.3e-19 69.0 6.2 3.4e-10 40.2 0.9 3.4 4 1 0 4 4 4 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFY00289.1 - 2.5e-18 66.2 0.1 2.9e-09 36.8 0.1 2.8 3 0 0 3 3 3 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFY00289.1 - 2.3e-07 30.2 0.0 0.002 17.3 0.0 4.0 3 1 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 KFY00289.1 - 2.7e-05 23.8 0.1 0.01 15.4 0.1 2.6 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KFY00289.1 - 0.0023 17.5 0.0 0.026 14.0 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.8 KFY00289.1 - 0.003 17.0 0.0 0.01 15.2 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) AXE1 PF05448.7 KFY00289.1 - 0.1 11.1 0.0 7.7 4.9 0.0 2.3 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.3 KFY00289.1 - 0.16 11.8 0.6 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 Putative lysophospholipase LRR_4 PF12799.2 KFY00289.1 - 3.6 7.3 6.6 11 5.7 0.2 3.7 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Asp_protease PF09668.5 KFY00290.1 - 1.4e-05 24.6 0.0 0.017 14.6 0.0 3.3 2 1 1 3 3 3 2 Aspartyl protease Asp_protease_2 PF13650.1 KFY00290.1 - 0.0001 22.7 0.0 0.01 16.2 0.0 2.7 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.1 KFY00290.1 - 0.0023 17.6 0.0 0.23 11.2 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 KFY00290.1 - 0.11 12.3 0.0 15 5.5 0.0 3.3 3 0 0 3 3 3 0 Retroviral aspartyl protease zf-C2H2_4 PF13894.1 KFY00290.1 - 4.7 7.7 25.1 0.44 10.9 1.0 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFY00290.1 - 5.4 7.5 18.5 0.027 14.7 1.8 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type Esterase PF00756.15 KFY00296.1 - 6.1e-46 156.8 0.0 7e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KFY00296.1 - 1.6e-06 27.9 0.0 2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 KFY00296.1 - 5.2e-06 25.8 0.0 0.00046 19.5 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KFY00296.1 - 0.00047 19.4 0.0 0.00082 18.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 KFY00296.1 - 0.00087 18.2 0.0 0.0019 17.1 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 KFY00296.1 - 0.0014 18.5 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 KFY00296.1 - 0.0031 16.3 0.0 0.085 11.6 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase AXE1 PF05448.7 KFY00296.1 - 0.0094 14.4 0.0 0.013 14.0 0.0 1.1 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 KFY00296.1 - 0.014 14.9 0.0 0.044 13.3 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KFY00296.1 - 0.065 12.6 0.0 0.12 11.7 0.0 1.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.8 KFY00296.1 - 0.1 10.9 0.0 0.18 10.0 0.0 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II PGAP1 PF07819.8 KFY00296.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.8 KFY00296.1 - 0.15 11.6 0.0 0.89 9.0 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Afi1 PF07792.7 KFY00297.1 - 5.8e-66 220.9 0.0 1.3e-65 219.8 0.0 1.6 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 KFY00297.1 - 8.4e-39 131.7 0.0 1.7e-38 130.8 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KFY00297.1 - 7.4e-09 34.5 0.0 0.0075 14.7 0.0 4.0 3 1 1 4 4 4 3 Transport protein Avl9 DUF2347 PF09804.4 KFY00297.1 - 0.0071 15.6 0.0 0.068 12.4 0.0 2.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) EF-hand_6 PF13405.1 KFY00298.1 - 3.1e-12 45.2 1.0 3e-05 23.5 0.3 2.6 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KFY00298.1 - 3.5e-11 41.5 1.1 0.00021 20.3 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 KFY00298.1 - 1.9e-08 34.3 0.7 7.7e-07 29.1 0.5 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 KFY00298.1 - 4.4e-07 28.9 4.8 0.0007 18.8 0.7 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KFY00298.1 - 7.7e-06 25.4 0.4 0.032 13.8 0.0 2.6 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.1 KFY00298.1 - 0.00063 19.6 0.0 0.36 10.7 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain MoeA_C PF03454.10 KFY00298.1 - 0.015 15.1 0.3 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 MoeA C-terminal region (domain IV) ORC6 PF05460.8 KFY00298.1 - 0.49 9.4 11.5 0.67 8.9 8.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Sugar_tr PF00083.19 KFY00300.1 - 2.1e-16 59.5 4.0 2.4e-16 59.3 2.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Claudin_3 PF06653.6 KFY00300.1 - 0.4 10.3 2.4 0.58 9.8 1.7 1.1 1 0 0 1 1 1 0 Tight junction protein, Claudin-like Xpo1 PF08389.7 KFY00301.1 - 3.4e-38 130.8 0.1 2.9e-37 127.8 0.0 2.7 2 0 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.17 KFY00301.1 - 0.0045 16.9 0.2 24 5.3 0.0 4.4 4 0 0 4 4 4 2 HEAT repeat Med10 PF09748.4 KFY00302.1 - 7.4e-38 129.2 0.0 8.6e-38 129.0 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF4451 PF14616.1 KFY00303.1 - 3.9e-35 120.3 0.4 7.6e-35 119.3 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Zn_clus PF00172.13 KFY00305.1 - 7e-06 25.8 9.0 1.2e-05 25.1 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.18 KFY00309.1 - 0.0014 18.4 0.0 0.0069 16.1 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Abhydrolase_3 PF07859.8 KFY00311.1 - 5.1e-34 117.6 0.0 1.5e-23 83.4 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.23 KFY00311.1 - 3.9e-06 25.8 0.0 7.8e-06 24.8 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KFY00311.1 - 0.0043 16.8 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Mito_carr PF00153.22 KFY00312.1 - 5e-60 199.2 4.7 1.9e-20 72.3 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 KFY00313.1 - 8e-18 63.5 0.1 5e-11 42.0 0.2 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF4613 PF15390.1 KFY00313.1 - 0.0068 14.6 0.0 0.01 14.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4613) NAD_binding_10 PF13460.1 KFY00315.1 - 9.2e-19 68.1 0.0 1.4e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFY00315.1 - 7.8e-05 22.0 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KFY00315.1 - 0.0035 16.8 0.0 0.0064 15.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFY00315.1 - 0.028 13.1 0.0 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KFY00315.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF4499 PF14934.1 KFY00317.1 - 0.081 12.8 1.8 0.15 12.0 0.2 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4499) EnY2 PF10163.4 KFY00319.1 - 0.00025 20.8 0.0 0.00038 20.3 0.0 1.3 1 0 0 1 1 1 1 Transcription factor e(y)2 Spidroin_MaSp PF11260.3 KFY00319.1 - 0.077 13.0 0.0 0.14 12.2 0.0 1.5 1 1 0 1 1 1 0 Major ampullate spidroin 1 and 2 COX5B PF01215.14 KFY00320.1 - 9.2e-38 128.9 0.0 1.2e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Zn-ribbon_8 PF09723.5 KFY00320.1 - 0.054 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Zinc ribbon domain RRN7 PF11781.3 KFY00320.1 - 0.092 12.2 0.1 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 ADK_lid PF05191.9 KFY00320.1 - 0.17 11.5 2.2 0.31 10.7 1.6 1.4 1 0 0 1 1 1 0 Adenylate kinase, active site lid AAA PF00004.24 KFY00321.1 - 4e-97 321.4 0.0 2.1e-47 160.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KFY00321.1 - 5.9e-20 71.0 0.3 1.8e-19 69.4 0.2 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_33 PF13671.1 KFY00321.1 - 1.1e-13 51.3 0.0 2.6e-06 27.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_2 PF07724.9 KFY00321.1 - 1.3e-13 51.2 0.0 2.3e-07 30.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KFY00321.1 - 5.6e-13 48.4 0.0 2.3e-05 23.5 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KFY00321.1 - 6.8e-12 45.3 0.6 4.1e-06 26.5 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KFY00321.1 - 1.4e-11 45.2 0.0 0.00039 21.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KFY00321.1 - 2.3e-11 43.9 0.2 0.0022 18.1 0.0 4.4 3 2 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KFY00321.1 - 3.7e-10 40.1 0.6 0.0011 18.9 0.0 3.8 3 2 1 4 4 3 2 AAA ATPase domain TIP49 PF06068.8 KFY00321.1 - 3.9e-09 35.7 0.0 0.0013 17.5 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 KFY00321.1 - 1e-07 31.5 0.0 0.012 15.0 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 KFY00321.1 - 1.2e-07 31.6 0.0 0.0061 16.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain CDC48_2 PF02933.12 KFY00321.1 - 2.5e-07 30.2 0.0 6.6e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Zeta_toxin PF06414.7 KFY00321.1 - 3.3e-07 29.5 0.0 0.0049 15.9 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.16 KFY00321.1 - 4.6e-07 29.2 0.2 0.031 13.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 KFY00321.1 - 4.7e-07 29.4 1.9 0.014 15.0 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain AAA_25 PF13481.1 KFY00321.1 - 5.5e-07 29.1 5.1 0.073 12.4 0.0 4.4 2 2 1 4 4 4 2 AAA domain RNA_helicase PF00910.17 KFY00321.1 - 2.5e-06 27.6 0.0 0.034 14.3 0.0 2.9 3 0 0 3 3 2 2 RNA helicase KaiC PF06745.8 KFY00321.1 - 2.7e-06 26.6 0.7 0.52 9.3 0.0 3.4 2 1 1 3 3 3 2 KaiC AAA_18 PF13238.1 KFY00321.1 - 4.5e-06 26.9 0.0 0.048 13.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 KFY00321.1 - 1.3e-05 25.1 0.0 0.0076 16.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 KFY00321.1 - 1.5e-05 25.0 0.0 0.19 11.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 KFY00321.1 - 1.7e-05 23.8 0.0 0.012 14.5 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_24 PF13479.1 KFY00321.1 - 3e-05 23.7 0.0 0.13 11.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain Sigma54_activat PF00158.21 KFY00321.1 - 3e-05 23.5 0.0 0.29 10.5 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KFY00321.1 - 3.2e-05 23.9 0.0 0.17 11.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 KFY00321.1 - 3.7e-05 23.0 0.2 0.31 10.2 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein ABC_tran PF00005.22 KFY00321.1 - 5.7e-05 23.4 0.0 0.28 11.5 0.0 3.3 2 1 0 2 2 2 1 ABC transporter Parvo_NS1 PF01057.12 KFY00321.1 - 7.1e-05 21.8 0.0 0.068 12.0 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 KFY00321.1 - 8.7e-05 22.3 0.0 5.5 6.6 0.0 4.0 2 2 2 4 4 4 0 Archaeal ATPase AAA_3 PF07726.6 KFY00321.1 - 0.00041 19.9 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KFY00321.1 - 0.00058 19.4 0.0 0.81 9.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Bac_DnaA PF00308.13 KFY00321.1 - 0.00066 19.3 0.0 1.9 8.0 0.0 2.9 3 0 0 3 3 2 2 Bacterial dnaA protein AAA_11 PF13086.1 KFY00321.1 - 0.00067 19.2 0.0 0.82 9.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.5 KFY00321.1 - 0.00072 19.3 0.1 0.003 17.4 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain NACHT PF05729.7 KFY00321.1 - 0.0011 18.6 0.0 1.5 8.4 0.0 3.3 3 0 0 3 3 3 1 NACHT domain DUF2075 PF09848.4 KFY00321.1 - 0.0012 17.8 0.0 0.5 9.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 KFY00321.1 - 0.0022 17.7 0.8 1 9.0 0.0 4.2 4 0 0 4 4 4 1 NTPase NB-ARC PF00931.17 KFY00321.1 - 0.0031 16.4 0.1 0.57 8.9 0.0 2.8 3 0 0 3 3 3 1 NB-ARC domain Viral_helicase1 PF01443.13 KFY00321.1 - 0.01 15.4 0.0 0.56 9.6 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase IPT PF01745.11 KFY00321.1 - 0.013 14.6 0.0 1.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.9 KFY00321.1 - 0.018 14.0 0.0 1 8.2 0.0 2.7 2 1 0 3 3 3 0 KAP family P-loop domain AAA_10 PF12846.2 KFY00321.1 - 0.042 13.2 0.7 10 5.4 0.0 3.6 3 1 1 4 4 4 0 AAA-like domain SKI PF01202.17 KFY00321.1 - 0.044 13.6 0.1 3.6 7.4 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase KTI12 PF08433.5 KFY00321.1 - 0.062 12.4 0.2 19 4.3 0.0 3.0 3 0 0 3 3 3 0 Chromatin associated protein KTI12 MobB PF03205.9 KFY00321.1 - 0.09 12.4 0.2 4.9 6.8 0.0 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 KFY00321.1 - 0.13 11.8 0.1 12 5.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zot PF05707.7 KFY00321.1 - 0.19 11.1 0.3 31 3.9 0.1 3.4 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) DUF1628 PF07790.6 KFY00323.1 - 0.022 15.5 0.4 0.046 14.4 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) PAN_1 PF00024.21 KFY00323.1 - 0.078 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 PAN domain Shisa PF13908.1 KFY00323.1 - 0.22 11.6 1.9 0.35 11.0 1.0 1.5 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator SoxE PF06525.6 KFY00323.1 - 0.74 9.0 6.8 3.4 6.8 4.1 2.4 1 1 1 2 2 2 0 Sulfocyanin (SoxE) DUF3500 PF12006.3 KFY00324.1 - 2.2e-90 302.8 0.0 2.6e-90 302.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) FAD_binding_3 PF01494.14 KFY00325.1 - 5.6e-21 74.9 0.1 6.4e-12 45.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KFY00325.1 - 2.9e-08 33.6 0.4 7e-08 32.3 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFY00325.1 - 0.0007 18.5 2.2 0.0015 17.4 1.6 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KFY00325.1 - 0.0011 18.8 0.1 0.0019 18.1 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFY00325.1 - 0.0025 16.9 0.6 0.0047 16.0 0.2 1.6 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 KFY00325.1 - 0.0027 16.6 0.7 0.0027 16.6 0.5 2.1 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFY00325.1 - 0.0028 17.7 0.2 0.004 17.2 0.2 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFY00325.1 - 0.0044 17.3 0.2 0.02 15.2 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 KFY00325.1 - 0.0063 16.3 0.2 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 ThiF family Trp_halogenase PF04820.9 KFY00325.1 - 0.0077 14.9 0.2 0.014 14.0 0.1 1.4 1 0 0 1 1 1 1 Tryptophan halogenase NAD_Gly3P_dh_N PF01210.18 KFY00325.1 - 0.053 13.2 0.2 0.12 12.1 0.2 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 KFY00325.1 - 0.068 12.5 0.2 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.17 KFY00325.1 - 0.074 11.8 2.0 0.063 12.1 0.6 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 KFY00325.1 - 0.1 11.0 0.4 0.16 10.4 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Shikimate_DH PF01488.15 KFY00325.1 - 0.13 12.3 0.3 0.31 11.1 0.2 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 KFY00325.1 - 0.17 11.6 0.7 0.28 10.9 0.1 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding F420_oxidored PF03807.12 KFY00325.1 - 0.27 11.6 1.3 0.62 10.5 0.5 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MFS_1 PF07690.11 KFY00326.1 - 5.3e-40 137.2 22.3 5.3e-40 137.2 15.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY00326.1 - 1.4e-09 37.0 28.6 9.7e-08 31.0 19.8 3.1 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KFY00326.1 - 2.5e-08 32.6 6.1 2.1e-07 29.5 1.4 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KFY00326.1 - 0.00071 18.0 5.9 0.00071 18.0 4.1 2.7 2 1 0 3 3 3 1 MFS/sugar transport protein PUCC PF03209.10 KFY00326.1 - 0.0024 16.6 2.2 0.061 12.0 0.5 2.3 2 0 0 2 2 2 2 PUCC protein MFS_1_like PF12832.2 KFY00326.1 - 0.0055 16.4 1.5 0.37 10.6 0.0 3.7 3 1 0 3 3 3 1 MFS_1 like family zf-C2H2 PF00096.21 KFY00327.1 - 6e-09 35.7 11.9 2.6e-05 24.2 0.1 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type Fungal_trans PF04082.13 KFY00327.1 - 5.5e-06 25.4 0.0 9e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_6 PF13912.1 KFY00327.1 - 7.4e-05 22.5 8.9 0.15 12.0 0.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KFY00327.1 - 9.2e-05 22.5 10.9 0.034 14.4 3.5 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFY00327.1 - 0.00012 22.2 3.6 0.00012 22.2 2.5 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KFY00327.1 - 0.00063 19.8 1.1 0.23 11.6 0.4 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFY00327.1 - 0.088 13.0 0.8 17 5.7 0.0 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type LIM PF00412.17 KFY00327.1 - 0.18 11.9 2.5 0.45 10.6 1.7 1.7 1 1 0 1 1 1 0 LIM domain zf-BED PF02892.10 KFY00327.1 - 0.53 10.0 7.1 0.59 9.9 4.0 1.8 2 0 0 2 2 2 0 BED zinc finger Peptidase_C15 PF01470.12 KFY00329.1 - 0.09 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Pyroglutamyl peptidase Gp-FAR-1 PF05823.7 KFY00329.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) FAA_hydrolase PF01557.13 KFY00330.1 - 6.6e-52 176.1 0.0 2.1e-51 174.4 0.0 1.6 2 0 0 2 2 2 1 Fumarylacetoacetate (FAA) hydrolase family Cyanate_lyase PF02560.9 KFY00331.1 - 1.2e-30 104.8 0.1 1.6e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain Sigma70_r4_2 PF08281.7 KFY00331.1 - 0.0023 17.3 0.0 0.0074 15.7 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_3 PF01381.17 KFY00331.1 - 0.0037 17.0 0.1 0.0066 16.2 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix DUF3786 PF12654.2 KFY00331.1 - 0.012 14.9 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) HTH_31 PF13560.1 KFY00331.1 - 0.04 14.1 0.1 0.057 13.6 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Arm PF00514.18 KFY00332.1 - 4.3e-92 299.1 15.7 3.5e-13 48.8 0.1 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KFY00332.1 - 1.2e-26 92.7 3.4 2e-09 37.5 0.0 6.1 2 1 4 7 7 7 6 HEAT repeats IBB PF01749.15 KFY00332.1 - 1.1e-22 79.9 2.1 2.1e-22 79.0 1.5 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 KFY00332.1 - 4.2e-20 71.6 12.0 8.8e-09 35.6 0.1 6.2 5 1 2 7 7 7 3 HEAT-like repeat HEAT PF02985.17 KFY00332.1 - 2.4e-18 64.4 3.8 3.6e-05 23.4 0.0 7.1 8 0 0 8 8 7 4 HEAT repeat Arm_2 PF04826.8 KFY00332.1 - 1.4e-09 37.4 0.0 0.004 16.3 0.0 4.0 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 KFY00332.1 - 3.7e-05 22.2 0.0 0.0036 15.6 0.0 2.6 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 KFY00332.1 - 0.00033 20.5 0.6 2.1 8.2 0.0 4.9 3 1 0 5 5 5 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 KFY00332.1 - 0.004 15.4 0.1 0.31 9.2 0.0 2.8 2 1 0 2 2 2 1 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.11 KFY00332.1 - 0.017 15.5 3.5 1.9 9.1 0.0 4.5 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Mo25 PF08569.6 KFY00332.1 - 0.19 10.7 0.0 1.5 7.7 0.0 2.3 2 1 0 2 2 2 0 Mo25-like POT1 PF02765.12 KFY00333.1 - 2.1e-06 27.7 0.0 1.1e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 SHNi-TPR PF10516.4 KFY00341.1 - 3.7e-12 45.2 0.2 8.7e-12 44.0 0.1 1.6 1 0 0 1 1 1 1 SHNi-TPR DUF3824 PF12868.2 KFY00341.1 - 7.8e-05 23.6 10.1 7.8e-05 23.6 7.0 8.0 4 2 5 9 9 9 2 Domain of unknwon function (DUF3824) DUF2910 PF11139.3 KFY00341.1 - 1.3 8.1 15.5 15 4.6 1.0 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF2910) NIF PF03031.13 KFY00342.1 - 9e-28 96.9 0.0 2.5e-27 95.5 0.0 1.7 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase GRAM PF02893.15 KFY00342.1 - 8.4e-27 92.4 0.8 1.6e-15 56.3 0.0 3.5 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 KFY00342.1 - 2.6e-24 85.5 0.0 5.7e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 KFY00342.1 - 2.3e-12 47.0 0.0 1e-11 44.9 0.0 2.2 2 0 0 2 2 2 1 PH domain WD40 PF00400.27 KFY00342.1 - 5.2e-10 38.8 5.9 0.0066 16.2 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat PTCB-BRCT PF12738.2 KFY00342.1 - 8.7e-10 38.3 0.2 2.2e-09 37.0 0.1 1.8 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KFY00342.1 - 1.5e-05 25.0 0.0 3.8e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PH_8 PF15409.1 KFY00342.1 - 0.0011 19.0 0.0 0.0036 17.3 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 KFY00342.1 - 0.006 16.8 0.4 0.006 16.8 0.3 3.4 3 1 0 3 3 3 1 Pleckstrin homology domain UDPGT PF00201.13 KFY00342.1 - 0.048 12.2 0.0 0.084 11.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase PPR_2 PF13041.1 KFY00343.1 - 0.091 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 PPR repeat family SNF2_N PF00176.18 KFY00344.1 - 2.9e-66 223.2 0.0 4e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 KFY00344.1 - 1.3e-61 207.7 0.1 2.6e-61 206.8 0.1 1.5 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 KFY00344.1 - 6.6e-13 48.3 0.0 4.2e-12 45.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFY00344.1 - 0.00014 21.7 0.0 0.00027 20.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KFY00344.1 - 0.00016 20.5 0.0 0.00045 19.1 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_22 PF13401.1 KFY00344.1 - 0.075 13.1 0.2 0.97 9.5 0.1 2.6 2 1 0 2 2 2 0 AAA domain Mito_carr PF00153.22 KFY00345.1 - 1.5e-48 162.4 6.5 2.7e-19 68.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Erg28 PF03694.8 KFY00347.1 - 5.9e-19 68.1 0.0 7e-19 67.8 0.0 1.0 1 0 0 1 1 1 1 Erg28 like protein WSC PF01822.14 KFY00348.1 - 2.4e-08 33.7 3.9 2.4e-08 33.7 2.7 2.5 2 1 0 2 2 2 1 WSC domain NYN PF01936.13 KFY00349.1 - 0.0011 19.3 0.0 0.0056 16.9 0.0 2.1 1 1 0 1 1 1 1 NYN domain Rpn3_C PF08375.6 KFY00350.1 - 3.8e-24 84.8 1.5 9.7e-24 83.5 1.0 1.7 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 KFY00350.1 - 1.7e-19 70.0 0.4 4.3e-19 68.7 0.0 1.9 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.12 KFY00350.1 - 0.0027 17.4 0.2 0.013 15.3 0.2 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat UQ_con PF00179.21 KFY00353.1 - 1.1e-17 63.7 0.0 1.5e-17 63.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pantoate_transf PF02548.10 KFY00354.1 - 6.6e-105 349.9 0.2 7.8e-105 349.6 0.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 KFY00354.1 - 5.5e-07 29.0 0.7 7.2e-07 28.6 0.0 1.5 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase NanE PF04131.9 KFY00354.1 - 0.2 10.6 2.3 8.5 5.2 0.0 2.6 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase APG12 PF04110.8 KFY00355.1 - 2.5e-29 101.3 0.0 4.2e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 KFY00355.1 - 0.0022 17.9 0.0 0.0035 17.2 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Lipoprotein_21 PF14041.1 KFY00355.1 - 0.023 14.6 0.7 0.052 13.4 0.0 1.9 3 0 0 3 3 3 0 LppP/LprE lipoprotein Peptidase_M24 PF00557.19 KFY00356.1 - 4.3e-49 166.8 0.0 6e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KFY00356.1 - 2.7e-37 127.1 0.0 4.7e-37 126.3 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain RuBisCO_large PF00016.15 KFY00356.1 - 0.022 13.5 0.0 0.032 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Creatinase_N PF01321.13 KFY00356.1 - 0.045 14.2 0.0 0.15 12.5 0.0 2.0 2 0 0 2 2 2 0 Creatinase/Prolidase N-terminal domain Dfp1_Him1_M PF08630.5 KFY00357.1 - 2.1e-45 153.5 0.0 3.8e-45 152.6 0.0 1.4 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 KFY00357.1 - 3.2e-24 84.3 0.5 3.2e-24 84.3 0.4 1.9 2 0 0 2 2 2 1 DBF zinc finger PTCB-BRCT PF12738.2 KFY00357.1 - 0.0092 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain adh_short PF00106.20 KFY00358.1 - 5.3e-19 68.7 0.0 9.1e-19 67.9 0.0 1.4 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFY00358.1 - 4.8e-09 36.1 0.0 7.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFY00358.1 - 5e-07 29.3 0.0 7e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFY00358.1 - 0.021 13.7 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ribosomal_S2 PF00318.15 KFY00360.1 - 5.2e-48 163.0 0.0 9.5e-48 162.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S2 CBS PF00571.23 KFY00360.1 - 2.3e-39 132.9 9.7 9.2e-11 41.3 0.0 4.8 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 KFY00360.1 - 6.9e-10 38.4 0.0 2.1e-09 36.9 0.0 1.9 1 0 0 1 1 1 1 PB1 domain zf-H2C2_2 PF13465.1 KFY00361.1 - 1.3e-07 31.5 19.4 0.00029 20.9 2.1 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 KFY00361.1 - 5.8e-06 26.3 29.5 0.00074 19.7 5.1 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFY00361.1 - 0.058 13.7 25.8 0.58 10.6 0.4 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger Bunya_G2 PF03563.8 KFY00361.1 - 1.1 8.1 3.1 1.6 7.5 2.1 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 Nup188 PF10487.4 KFY00371.1 - 2.7e-44 151.3 0.0 1.2e-43 149.2 0.0 1.9 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 DUF1754 PF08555.5 KFY00371.1 - 2.8e-05 24.6 3.3 6.2e-05 23.5 2.3 1.6 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) IGPS PF00218.16 KFY00372.1 - 2.9e-93 311.5 0.0 4.9e-93 310.8 0.0 1.4 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 KFY00372.1 - 1.4e-54 184.6 0.4 5.7e-52 176.1 0.1 2.6 2 1 1 3 3 3 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 KFY00372.1 - 2.8e-51 173.7 0.0 4.8e-51 172.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KFY00372.1 - 5.1e-05 22.8 0.0 0.00013 21.5 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 KFY00372.1 - 0.0082 15.6 1.3 0.16 11.4 0.1 2.8 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.16 KFY00372.1 - 0.021 14.0 0.1 0.066 12.4 0.0 1.9 2 0 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.9 KFY00372.1 - 0.052 12.5 0.1 0.27 10.1 0.0 2.0 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase BRCT PF00533.21 KFY00373.1 - 2.4e-09 37.1 0.0 5.2e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Nop16 PF09420.5 KFY00373.1 - 0.021 14.9 0.0 0.037 14.1 0.0 1.4 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 Rad17 PF03215.10 KFY00386.1 - 2.2e-60 204.8 0.0 7.5e-60 203.0 0.0 1.7 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KFY00386.1 - 0.0001 22.4 0.0 0.00021 21.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KFY00386.1 - 0.00055 20.1 0.2 0.0022 18.1 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KFY00386.1 - 0.0013 18.4 0.1 0.0039 16.9 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KFY00386.1 - 0.0063 16.1 0.1 0.014 14.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFY00386.1 - 0.012 15.3 0.1 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KFY00386.1 - 0.014 16.1 0.0 0.036 14.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KFY00386.1 - 0.018 14.1 0.0 0.032 13.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 KFY00386.1 - 0.03 14.6 0.0 0.057 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KFY00386.1 - 0.036 14.0 0.1 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain DUF853 PF05872.7 KFY00386.1 - 0.039 12.3 1.1 0.12 10.7 0.2 2.0 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF853) AAA_28 PF13521.1 KFY00386.1 - 0.075 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KFY00386.1 - 0.077 12.6 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KFY00386.1 - 0.12 11.9 0.3 0.26 10.9 0.2 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 KFY00386.1 - 0.17 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase p450 PF00067.17 KFY00387.1 - 2.9e-44 151.3 0.0 2.5e-43 148.2 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Pro-kuma_activ PF09286.6 KFY00388.1 - 1.3e-34 119.2 0.0 2.4e-34 118.4 0.0 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KFY00388.1 - 2.7e-09 36.6 0.0 5.6e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Subtilase family FA_desaturase PF00487.19 KFY00389.1 - 1e-39 136.5 22.0 1.7e-39 135.8 15.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3821 PF12863.2 KFY00389.1 - 0.12 12.0 0.1 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) EST1_DNA_bind PF10373.4 KFY00398.1 - 1.7e-09 37.3 0.1 3.9e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain RIC3 PF15361.1 KFY00399.1 - 0.028 14.6 0.5 0.32 11.2 1.5 1.7 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 DUF2101 PF09874.4 KFY00399.1 - 0.1 12.0 4.6 0.15 11.5 3.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) ELO PF01151.13 KFY00399.1 - 0.12 11.6 2.6 0.2 10.9 1.8 1.4 1 0 0 1 1 1 0 GNS1/SUR4 family ATP-synt_F PF01990.12 KFY00405.1 - 3.9e-32 110.4 0.1 4.6e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit E1_DerP2_DerF2 PF02221.10 KFY00406.1 - 3.3e-25 88.8 0.2 3.9e-25 88.6 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 KFY00406.1 - 0.0027 17.7 0.1 0.0062 16.5 0.1 1.6 1 1 0 1 1 1 1 ML-like domain NPCBM_assoc PF10633.4 KFY00406.1 - 0.049 13.6 0.1 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Alph_Pro_TM PF09608.5 KFY00406.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) PHD PF00628.24 KFY00407.1 - 2.6e-07 30.2 8.8 4.9e-07 29.3 6.1 1.5 1 0 0 1 1 1 1 PHD-finger Glycos_transf_4 PF00953.16 KFY00408.1 - 6.5e-31 107.2 7.9 6.5e-31 107.2 5.5 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 4 WD40 PF00400.27 KFY00409.1 - 2.1e-21 74.9 3.7 7.6e-06 25.6 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ECM11 PF15463.1 KFY00412.1 - 3.6e-31 108.3 1.2 1.2e-30 106.6 0.0 2.2 2 0 0 2 2 2 1 Extracellular mutant protein 11 AAA_17 PF13207.1 KFY00413.1 - 0.0012 19.7 0.5 0.0051 17.6 0.3 2.1 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 KFY00413.1 - 0.0029 16.6 0.0 0.0052 15.8 0.0 1.3 1 1 0 1 1 1 1 KAP family P-loop domain ArgK PF03308.11 KFY00413.1 - 0.003 16.3 0.0 0.0048 15.6 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_18 PF13238.1 KFY00413.1 - 0.0048 17.1 0.0 0.014 15.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFY00413.1 - 0.008 16.1 0.1 0.01 15.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain PRK PF00485.13 KFY00413.1 - 0.067 12.7 0.0 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.17 KFY00413.1 - 0.068 12.6 0.0 0.097 12.1 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 KFY00413.1 - 0.095 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 KFY00413.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain adh_short PF00106.20 KFY00415.1 - 3.3e-61 206.0 8.6 3.2e-30 105.2 1.3 2.4 2 0 0 2 2 2 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 KFY00415.1 - 2.8e-31 107.4 0.0 5.8e-31 106.4 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 KFY00415.1 - 1.8e-29 102.6 4.1 5.3e-14 52.2 0.2 2.6 3 0 0 3 3 3 2 KR domain MaoC_dehydrat_N PF13452.1 KFY00415.1 - 1.2e-10 41.2 0.0 6.2e-09 35.7 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.14 KFY00415.1 - 3.3e-06 26.2 0.3 3.8e-05 22.8 0.1 2.3 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4161 PF13722.1 KFY00415.1 - 0.017 15.4 0.5 2.5 8.3 0.0 2.3 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) Eno-Rase_NADH_b PF12242.3 KFY00415.1 - 0.021 14.6 3.5 0.25 11.1 0.3 2.6 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF2099 PF09872.4 KFY00415.1 - 0.21 10.6 1.4 0.49 9.3 0.1 2.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2099) DUF543 PF04418.7 KFY00415.1 - 3.2 7.7 8.0 4.5 7.2 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF543) AMP-binding PF00501.23 KFY00416.1 - 3.1e-83 279.4 0.0 5e-83 278.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFY00416.1 - 0.02 15.8 0.1 0.05 14.5 0.1 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Methyltransf_16 PF10294.4 KFY00418.1 - 4e-13 49.2 0.0 5.2e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase DUF3292 PF11696.3 KFY00419.1 - 4.7e-219 728.5 0.0 7.2e-219 727.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) p450 PF00067.17 KFY00419.1 - 1.6e-27 96.1 0.0 1e-26 93.5 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Ribosomal_L1 PF00687.16 KFY00422.1 - 2.8e-58 196.8 0.6 2.8e-58 196.8 0.4 1.9 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Nbl1_Borealin_N PF10444.4 KFY00422.1 - 0.015 14.6 0.1 0.058 12.7 0.1 2.0 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal ORC6 PF05460.8 KFY00430.1 - 0.046 12.8 0.5 0.042 12.9 0.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SWI-SNF_Ssr4 PF08549.5 KFY00430.1 - 0.059 11.6 0.0 0.063 11.5 0.0 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) AAA PF00004.24 KFY00431.1 - 1.6e-45 154.5 0.7 5.5e-45 152.7 0.0 2.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFY00431.1 - 3.8e-09 36.3 0.6 1.2e-08 34.8 0.1 2.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KFY00431.1 - 4.2e-08 33.3 0.0 8.9e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KFY00431.1 - 4.2e-07 30.1 0.0 1.4e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFY00431.1 - 7.7e-07 29.3 0.6 0.001 19.1 0.0 2.8 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 KFY00431.1 - 3e-06 26.3 0.0 5.9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 KFY00431.1 - 0.00012 21.9 0.0 0.00058 19.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KFY00431.1 - 0.00029 19.9 0.0 0.00065 18.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KFY00431.1 - 0.00033 21.4 0.0 0.0019 19.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KFY00431.1 - 0.00043 20.2 0.0 0.00088 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KFY00431.1 - 0.00076 19.1 1.0 0.057 13.0 0.0 3.2 3 1 0 3 3 3 1 NACHT domain UPF0079 PF02367.12 KFY00431.1 - 0.00092 18.8 0.1 0.04 13.5 0.0 2.3 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 KFY00431.1 - 0.0011 18.0 0.0 0.0039 16.2 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 KFY00431.1 - 0.0013 18.4 0.2 0.0032 17.1 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 KFY00431.1 - 0.0014 18.7 0.0 0.0033 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.10 KFY00431.1 - 0.0031 17.2 0.0 0.0092 15.6 0.0 1.8 1 0 0 1 1 1 1 NTPase AAA_3 PF07726.6 KFY00431.1 - 0.0038 16.8 0.0 0.011 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 KFY00431.1 - 0.0049 15.6 0.0 0.0086 14.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_11 PF13086.1 KFY00431.1 - 0.005 16.4 0.7 0.018 14.6 0.0 2.1 2 1 1 3 3 3 1 AAA domain AAA_23 PF13476.1 KFY00431.1 - 0.0055 17.0 0.7 0.9 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KFY00431.1 - 0.0056 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFY00431.1 - 0.0058 16.0 0.7 0.054 12.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KFY00431.1 - 0.0066 15.6 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KFY00431.1 - 0.007 15.9 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KFY00431.1 - 0.0071 16.0 0.8 0.061 13.0 0.0 2.6 2 1 1 3 3 3 1 Archaeal ATPase IstB_IS21 PF01695.12 KFY00431.1 - 0.01 15.2 0.3 0.025 13.9 0.0 1.7 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_24 PF13479.1 KFY00431.1 - 0.014 14.9 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 KFY00431.1 - 0.018 14.6 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein KaiC PF06745.8 KFY00431.1 - 0.025 13.6 0.8 0.45 9.5 0.0 2.6 3 0 0 3 3 3 0 KaiC AAA_18 PF13238.1 KFY00431.1 - 0.028 14.7 0.0 0.089 13.0 0.0 2.0 2 1 0 2 2 1 0 AAA domain Sigma54_activat PF00158.21 KFY00431.1 - 0.048 13.1 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KFY00431.1 - 0.054 13.5 0.1 0.31 11.0 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain Viral_Hsp90 PF03225.9 KFY00431.1 - 0.066 11.5 0.0 0.1 10.8 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue NB-ARC PF00931.17 KFY00431.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 KFY00431.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 SHMT PF00464.14 KFY00432.1 - 2.6e-207 687.9 0.0 3e-207 687.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 KFY00432.1 - 1.8e-05 23.7 0.0 2.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KFY00432.1 - 6.5e-05 22.0 0.0 0.00015 20.8 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KFY00432.1 - 0.008 15.3 0.0 0.012 14.7 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Baculo_DNA_bind PF04786.7 KFY00432.1 - 0.07 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 ssDNA binding protein Nop PF01798.13 KFY00433.1 - 4.9e-60 201.1 0.1 9.1e-60 200.3 0.1 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KFY00433.1 - 1.8e-25 88.5 0.1 4.8e-25 87.1 0.1 1.8 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KFY00433.1 - 2.8e-21 75.4 0.0 2.8e-21 75.4 0.0 2.7 4 0 0 4 4 4 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 KFY00433.1 - 0.35 10.5 20.7 0.74 9.4 14.4 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 AAA PF00004.24 KFY00434.1 - 1.4e-38 132.0 0.1 3.2e-38 130.9 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KFY00434.1 - 8.4e-29 99.2 0.1 2.9e-28 97.5 0.0 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 KFY00434.1 - 4e-22 77.8 3.5 1e-21 76.5 2.4 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.7 KFY00434.1 - 7.4e-07 28.4 0.0 1.2e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KFY00434.1 - 2.2e-06 28.5 0.2 2.2e-05 25.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFY00434.1 - 7.4e-06 26.1 0.0 0.0049 16.9 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 KFY00434.1 - 8.5e-06 25.7 0.4 0.0052 16.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 KFY00434.1 - 5.2e-05 22.7 0.3 0.19 11.1 0.1 2.6 1 1 1 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KFY00434.1 - 5.2e-05 22.7 0.0 0.00012 21.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 KFY00434.1 - 8.8e-05 22.2 0.0 0.00043 20.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KFY00434.1 - 0.00011 22.0 0.0 0.00024 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KFY00434.1 - 0.00018 20.4 0.0 0.0007 18.5 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 KFY00434.1 - 0.00035 20.6 0.0 0.0015 18.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KFY00434.1 - 0.00035 20.4 0.0 0.00075 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KFY00434.1 - 0.00064 18.8 0.1 0.41 9.7 0.0 2.4 1 1 1 2 2 2 2 Zeta toxin USP8_dimer PF08969.6 KFY00434.1 - 0.00097 19.0 2.4 0.0021 18.0 1.6 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain RNA_helicase PF00910.17 KFY00434.1 - 0.0011 19.0 0.0 0.014 15.5 0.0 2.4 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.8 KFY00434.1 - 0.0024 16.6 0.0 0.0038 15.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 KFY00434.1 - 0.0076 15.4 0.0 0.019 14.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Peptidase_M28 PF04389.12 KFY00434.1 - 0.0082 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Sigma54_activat PF00158.21 KFY00434.1 - 0.032 13.7 0.0 0.42 10.0 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 KFY00434.1 - 0.032 13.9 0.2 1.6 8.3 0.0 2.8 2 1 1 3 3 3 0 Archaeal ATPase KaiC PF06745.8 KFY00434.1 - 0.041 13.0 0.1 6.8 5.7 0.0 2.4 1 1 1 2 2 2 0 KaiC PhoH PF02562.11 KFY00434.1 - 0.054 12.7 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 KFY00434.1 - 0.065 12.8 0.8 0.16 11.4 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 KFY00434.1 - 0.069 12.5 0.2 0.87 8.9 0.1 2.2 2 0 0 2 2 2 0 AAA-like domain ResIII PF04851.10 KFY00434.1 - 0.069 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KFY00434.1 - 0.094 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Torsin PF06309.6 KFY00434.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_18 PF13238.1 KFY00434.1 - 0.11 12.7 0.2 0.46 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KFY00434.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Prefoldin_2 PF01920.15 KFY00435.1 - 5.2e-22 77.6 11.0 6.1e-22 77.3 7.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 KFY00435.1 - 0.00019 21.1 4.5 0.00024 20.8 3.1 1.2 1 0 0 1 1 1 1 Prefoldin subunit IncA PF04156.9 KFY00435.1 - 0.007 15.9 13.1 0.045 13.3 9.1 1.9 1 1 0 1 1 1 1 IncA protein Spc24 PF08286.6 KFY00435.1 - 0.0078 15.9 2.2 0.0078 15.9 1.6 2.0 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 HALZ PF02183.13 KFY00435.1 - 0.02 14.6 2.2 0.91 9.2 0.9 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper DivIC PF04977.10 KFY00435.1 - 0.022 14.2 13.5 0.58 9.6 0.3 2.8 2 1 0 2 2 2 0 Septum formation initiator YgaB PF14182.1 KFY00435.1 - 0.023 14.9 0.9 0.023 14.9 0.6 2.2 2 0 0 2 2 2 0 YgaB-like protein DUF2353 PF09789.4 KFY00435.1 - 0.035 13.3 1.3 0.035 13.3 0.9 1.9 1 1 0 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) Prefoldin PF02996.12 KFY00435.1 - 0.062 12.9 7.1 0.96 9.1 0.6 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF3571 PF12095.3 KFY00435.1 - 0.074 13.2 4.9 1.9 8.7 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3571) Spc7 PF08317.6 KFY00435.1 - 0.11 11.1 9.1 0.13 10.9 6.3 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein PAD PF03068.10 KFY00435.1 - 0.12 10.7 0.5 0.14 10.5 0.4 1.0 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) DUF4201 PF13870.1 KFY00435.1 - 0.16 11.4 6.0 2.4 7.5 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DASH_Dad3 PF08656.5 KFY00435.1 - 0.35 10.5 4.0 1.2 8.9 2.7 2.0 1 1 0 1 1 1 0 DASH complex subunit Dad3 Tropomyosin_1 PF12718.2 KFY00435.1 - 0.37 10.6 11.8 0.42 10.4 3.2 2.1 2 0 0 2 2 2 0 Tropomyosin like Taxilin PF09728.4 KFY00435.1 - 0.43 9.6 9.8 1.6 7.7 6.7 1.9 1 1 0 1 1 1 0 Myosin-like coiled-coil protein Occludin_ELL PF07303.8 KFY00435.1 - 0.69 10.6 4.1 1.3 9.7 1.2 1.9 1 1 1 2 2 2 0 Occludin homology domain DUF1192 PF06698.6 KFY00435.1 - 0.85 9.4 5.9 0.71 9.7 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) BRE1 PF08647.6 KFY00435.1 - 1 9.3 7.1 1.3 9.0 0.3 2.3 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase CENP-F_leu_zip PF10473.4 KFY00435.1 - 1.5 8.7 9.1 0.61 9.9 1.8 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMPIT PF07851.8 KFY00435.1 - 2 7.3 5.0 2.4 7.1 3.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein Endonuc-BglII PF09195.6 KFY00435.1 - 2.2 7.7 5.4 4.6 6.6 0.3 2.0 1 1 1 2 2 2 0 Restriction endonuclease BglII DUF4140 PF13600.1 KFY00435.1 - 2.2 8.7 11.1 2.1 8.8 0.4 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4570 PF15134.1 KFY00435.1 - 2.2 8.1 6.5 5.2 6.9 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4570) DUF4407 PF14362.1 KFY00435.1 - 2.3 7.0 11.1 2.9 6.7 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mnd1 PF03962.10 KFY00435.1 - 3.1 7.4 11.0 0.41 10.2 2.9 1.9 1 1 1 2 2 2 0 Mnd1 family NPV_P10 PF05531.7 KFY00435.1 - 3.3 8.0 7.8 8.1 6.7 1.0 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Cep57_CLD_2 PF14197.1 KFY00435.1 - 6.4 6.7 7.4 4.9 7.1 0.6 2.6 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 APG6 PF04111.7 KFY00435.1 - 9.4 5.1 11.1 74 2.2 7.7 1.9 1 1 0 1 1 1 0 Autophagy protein Apg6 TMF_TATA_bd PF12325.3 KFY00435.1 - 9.6 5.9 12.0 11 5.7 0.9 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Ank_2 PF12796.2 KFY00439.1 - 2e-197 640.1 19.0 9e-25 86.8 0.0 6.8 1 1 10 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 KFY00439.1 - 1.1e-115 372.1 1.3 1.3e-08 34.2 0.0 13.6 13 1 0 13 13 13 12 Ankyrin repeat Ank_3 PF13606.1 KFY00439.1 - 1.1e-85 272.8 0.0 1.5e-05 24.8 0.0 13.5 13 1 0 13 13 13 12 Ankyrin repeat Ank_4 PF13637.1 KFY00439.1 - 3.4e-78 256.7 5.3 4.1e-09 36.7 0.0 10.1 1 1 10 12 12 12 12 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY00439.1 - 2.3e-67 221.4 10.1 2.2e-10 40.4 0.0 12.2 2 1 11 13 13 13 13 Ankyrin repeats (many copies) DUF4350 PF14258.1 KFY00439.1 - 3.3e-08 33.6 10.2 15 5.8 0.0 10.3 10 2 2 12 12 12 0 Domain of unknown function (DUF4350) UDPG_MGDP_dh_C PF03720.10 KFY00439.1 - 6.3e-06 26.2 7.6 61 3.8 0.0 9.0 7 3 4 11 11 11 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain CXCL17 PF15211.1 KFY00439.1 - 0.0057 17.0 0.0 1e+02 3.4 0.0 6.0 5 1 4 9 9 9 0 VEGF co-regulated chemokine 1 PC_rep PF01851.17 KFY00439.1 - 0.37 11.1 10.5 1.7e+02 2.7 0.0 7.7 12 0 0 12 12 12 0 Proteasome/cyclosome repeat TPR_21 PF09976.4 KFY00439.1 - 4.6 7.1 15.4 1.3 8.9 0.8 5.0 1 1 7 8 8 8 0 Tetratricopeptide repeat Pkinase PF00069.20 KFY00446.1 - 7e-69 231.8 0.0 1.2e-68 231.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY00446.1 - 1.2e-42 145.8 0.0 1.6e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFY00446.1 - 9.5e-12 44.4 0.0 2.4e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFY00446.1 - 0.0043 16.8 9.5 1.5 8.4 0.1 3.9 2 2 2 4 4 4 2 Phosphotransferase enzyme family Kdo PF06293.9 KFY00446.1 - 0.015 14.3 0.0 0.038 13.0 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C3HC4_3 PF13920.1 KFY00447.1 - 7.5e-06 25.5 7.8 7.5e-06 25.5 5.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFY00447.1 - 8.9e-06 25.6 12.0 8.9e-06 25.6 8.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFY00447.1 - 1.4e-05 24.6 10.5 1.4e-05 24.6 7.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFY00447.1 - 3e-05 23.6 9.0 3e-05 23.6 6.2 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFY00447.1 - 3.1e-05 23.7 12.1 3.1e-05 23.7 8.4 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 KFY00447.1 - 4.6e-05 23.1 12.2 4.6e-05 23.1 8.4 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFY00447.1 - 0.00085 18.9 4.6 0.00085 18.9 3.2 1.8 2 0 0 2 2 1 1 RING-type zinc-finger Rhabdo_ncap PF00945.13 KFY00447.1 - 0.039 12.5 1.3 6 5.3 0.6 2.4 2 0 0 2 2 2 0 Rhabdovirus nucleocapsid protein UPF0547 PF10571.4 KFY00447.1 - 0.047 13.3 0.7 0.047 13.3 0.5 3.5 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 PhnA_Zn_Ribbon PF08274.7 KFY00447.1 - 0.18 11.6 5.1 0.46 10.2 0.1 3.1 3 0 0 3 3 3 0 PhnA Zinc-Ribbon DZR PF12773.2 KFY00447.1 - 1 9.2 15.1 0.32 10.8 0.8 2.8 2 1 1 3 3 3 0 Double zinc ribbon zinc_ribbon_5 PF13719.1 KFY00447.1 - 4.2 7.0 8.2 5.6 6.6 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KFY00447.1 - 5.3 6.8 8.0 9.7 5.9 0.1 3.9 4 0 0 4 4 4 0 zinc-ribbon domain Response_reg PF00072.19 KFY00461.1 - 1.9e-20 72.9 0.0 5.3e-14 52.1 0.0 2.9 2 1 1 3 3 3 2 Response regulator receiver domain PQ-loop PF04193.9 KFY00462.1 - 1.4e-11 43.7 9.3 4.2e-06 26.2 0.3 3.8 3 1 1 4 4 4 2 PQ loop repeat Pep_deformylase PF01327.16 KFY00462.1 - 0.18 11.1 0.1 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Polypeptide deformylase SNase PF00565.12 KFY00463.1 - 6.3e-68 225.8 0.9 4.1e-23 81.6 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 KFY00463.1 - 1.7e-23 82.7 0.0 6.6e-23 80.8 0.0 2.0 2 0 0 2 2 2 1 Tudor domain SMN PF06003.7 KFY00463.1 - 7.7e-05 21.9 0.0 0.00014 21.0 0.0 1.4 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) DUF1939 PF09154.5 KFY00465.1 - 0.042 13.7 0.1 0.068 13.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) DUF4413 PF14372.1 KFY00469.1 - 4.9e-05 23.2 0.5 0.00051 19.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) Dimer_Tnp_hAT PF05699.9 KFY00469.1 - 0.17 11.5 0.3 0.17 11.5 0.2 1.8 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region AAA PF00004.24 KFY00471.1 - 0.084 13.0 0.1 0.73 10.0 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 KFY00471.1 - 0.091 11.7 0.1 0.22 10.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) EssA PF10661.4 KFY00471.1 - 0.12 12.0 0.2 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA DUF2075 PF09848.4 KFY00473.1 - 0.067 12.1 0.1 0.13 11.1 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 KFY00473.1 - 0.079 12.7 0.2 0.68 9.7 0.0 2.3 1 1 1 2 2 2 0 Part of AAA domain AAA PF00004.24 KFY00473.1 - 0.086 13.0 0.1 0.55 10.4 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KFY00473.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Tom22 PF04281.8 KFY00479.1 - 5.7e-43 145.7 0.2 6.7e-43 145.5 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 PTCB-BRCT PF12738.2 KFY00480.1 - 8.1e-49 163.3 0.8 2.3e-21 75.4 0.0 3.9 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 KFY00480.1 - 2.3e-33 114.1 2.2 1.5e-13 50.6 0.0 5.4 5 1 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain Arrestin_N PF00339.24 KFY00481.1 - 9.1e-11 41.7 1.0 1.3e-06 28.2 0.0 3.1 4 0 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KFY00481.1 - 4.6e-08 33.2 0.0 2.8e-07 30.7 0.0 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Dynamin_N PF00350.18 KFY00482.1 - 2.8e-16 59.7 0.5 9.8e-16 58.0 0.0 2.2 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 KFY00482.1 - 1.2e-08 34.9 0.0 4.8e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KFY00482.1 - 6.8e-07 28.9 1.0 6.8e-06 25.6 0.4 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IIGP PF05049.8 KFY00482.1 - 0.016 14.0 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Herpes_UL6 PF01763.11 KFY00482.1 - 0.023 12.8 0.6 0.16 10.1 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus UL6 like DUF2205 PF10224.4 KFY00482.1 - 0.037 13.5 0.1 0.2 11.2 0.1 2.3 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) AAA_29 PF13555.1 KFY00482.1 - 0.067 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4404 PF14357.1 KFY00482.1 - 0.35 11.2 3.2 2.5 8.5 1.6 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Snf7 PF03357.16 KFY00483.1 - 2.2e-36 124.8 19.9 3.4e-36 124.2 13.8 1.3 1 0 0 1 1 1 1 Snf7 WASH_WAHD PF11945.3 KFY00483.1 - 0.023 13.9 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 WAHD domain of WASH complex Ist1 PF03398.9 KFY00483.1 - 0.071 12.5 5.8 0.12 11.7 4.0 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Peptidase_S46 PF10459.4 KFY00483.1 - 0.18 10.1 5.4 0.22 9.8 3.8 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF592 PF04574.8 KFY00483.1 - 0.67 9.4 3.9 7 6.1 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF592) DSBA PF01323.15 KFY00483.1 - 4.9 6.6 6.2 7.2 6.1 4.3 1.4 1 1 0 1 1 1 0 DSBA-like thioredoxin domain YlqD PF11068.3 KFY00483.1 - 7.4 6.6 18.2 2.1 8.3 5.4 2.2 1 1 1 2 2 2 0 YlqD protein PP2C PF00481.16 KFY00484.1 - 6.4e-63 212.5 0.7 9.2e-51 172.6 0.3 3.1 3 0 0 3 3 3 2 Protein phosphatase 2C Hs1pro-1_C PF07014.7 KFY00484.1 - 0.066 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus DUF4211 PF13926.1 KFY00485.1 - 8.7e-36 122.6 0.0 3.3e-35 120.7 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) DUF4449 PF14613.1 KFY00486.1 - 1.9e-63 213.2 1.3 1.9e-63 213.2 0.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) RasGEF PF00617.14 KFY00488.1 - 8.6e-63 211.4 0.0 1.4e-62 210.7 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KFY00488.1 - 1.4e-26 92.6 0.3 4.1e-26 91.0 0.2 1.9 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 KFY00488.1 - 7.4e-16 57.2 0.1 1.5e-15 56.2 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFY00488.1 - 2.6e-14 52.5 0.2 4.9e-14 51.6 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFY00488.1 - 2.5e-13 49.2 0.1 4.7e-13 48.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 KFY00488.1 - 2.6e-05 23.9 0.0 5.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 WW domain Ubie_methyltran PF01209.13 KFY00490.1 - 3.1e-20 72.3 0.0 4.7e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Glyco_transf_90 PF05686.7 KFY00490.1 - 0.012 14.3 0.0 0.014 14.1 0.0 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 90 E1_dh PF00676.15 KFY00491.1 - 3e-83 279.0 0.0 3.7e-83 278.7 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KFY00491.1 - 0.00015 21.3 0.1 0.0012 18.4 0.0 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_N PF00456.16 KFY00491.1 - 0.0023 16.8 0.0 0.0047 15.7 0.0 1.4 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain XFP_N PF09364.5 KFY00491.1 - 0.16 10.4 0.0 0.25 9.8 0.0 1.3 1 0 0 1 1 1 0 XFP N-terminal domain Smr PF01713.16 KFY00492.1 - 9.1e-11 41.8 0.4 2.3e-10 40.5 0.3 1.7 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 KFY00492.1 - 1.4e-06 28.2 6.6 3.2e-06 27.0 4.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) CUE PF02845.11 KFY00492.1 - 0.0015 18.0 0.0 0.0034 16.8 0.0 1.6 1 0 0 1 1 1 1 CUE domain DMA PF03474.9 KFY00492.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 DMRTA motif HECT PF00632.20 KFY00493.1 - 6.9e-81 271.8 0.0 1.1e-80 271.1 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.18 KFY00493.1 - 0.04 13.7 3.2 19 5.2 0.1 5.3 6 1 1 7 7 7 0 Armadillo/beta-catenin-like repeat NAD_binding_10 PF13460.1 KFY00508.1 - 0.00024 21.1 0.0 0.00041 20.3 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFY00508.1 - 0.00028 20.2 0.0 0.00038 19.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Skp1 PF01466.14 KFY00508.1 - 0.096 12.7 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Skp1 family, dimerisation domain YcaO PF02624.11 KFY00508.1 - 0.12 11.8 0.1 0.27 10.6 0.1 1.5 2 0 0 2 2 2 0 YcaO-like family Ank_2 PF12796.2 KFY00510.1 - 4.6e-29 100.5 6.3 6.2e-12 45.6 0.1 5.0 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFY00510.1 - 3e-26 91.2 10.8 4.1e-07 30.3 0.1 7.8 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY00510.1 - 1.5e-21 75.9 7.7 5.1e-08 32.9 0.2 6.6 3 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.25 KFY00510.1 - 4.4e-21 73.5 15.5 3.1e-06 26.7 0.1 8.6 9 0 0 9 9 9 6 Ankyrin repeat Ank_3 PF13606.1 KFY00510.1 - 3.1e-20 70.2 11.5 0.001 19.0 0.0 9.2 9 1 0 9 9 9 5 Ankyrin repeat pRN1_helical PF13010.1 KFY00510.1 - 0.076 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Primase helical domain MFS_1 PF07690.11 KFY00512.1 - 2.1e-11 43.1 15.1 2.7e-11 42.8 10.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.8 KFY00512.1 - 1.9e-09 37.1 4.0 2.2e-09 36.9 2.8 1.0 1 0 0 1 1 1 1 Nodulin-like Serinc PF03348.10 KFY00513.1 - 1.7e-174 580.5 4.8 2.1e-174 580.2 3.4 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Adipogenin PF15202.1 KFY00513.1 - 0.29 11.0 2.7 18 5.2 0.1 3.0 2 0 0 2 2 2 0 Adipogenin DUF2254 PF10011.4 KFY00513.1 - 0.73 8.2 5.7 0.21 10.0 0.2 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) Glyco_hydro_53 PF07745.8 KFY00514.1 - 4.6e-107 357.6 1.4 5.2e-107 357.4 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Cellulase PF00150.13 KFY00514.1 - 0.00034 19.9 2.1 0.00034 19.9 1.5 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4015 PF13200.1 KFY00514.1 - 0.022 13.6 0.7 0.27 10.1 0.1 2.0 1 1 0 2 2 2 0 Putative glycosyl hydrolase domain DUF2457 PF10446.4 KFY00516.1 - 1.4 7.5 22.6 2.2 6.9 15.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 KFY00516.1 - 2 7.6 14.6 2 7.6 9.4 1.4 2 0 0 2 2 2 0 NOA36 protein CobT PF06213.7 KFY00516.1 - 2.5 7.1 26.3 3.7 6.5 18.2 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Astro_capsid PF03115.9 KFY00516.1 - 6.3 4.9 4.8 8.4 4.5 3.3 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Pectinesterase PF01095.14 KFY00517.1 - 1.7e-41 141.7 1.4 2.5e-41 141.2 1.0 1.2 1 0 0 1 1 1 1 Pectinesterase Pec_lyase_C PF00544.14 KFY00518.1 - 9.2e-18 64.4 6.4 3.3e-17 62.6 4.4 1.9 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KFY00518.1 - 0.0011 18.7 15.1 0.0032 17.2 6.2 2.4 1 1 1 2 2 2 2 Right handed beta helix region adh_short PF00106.20 KFY00519.1 - 9.7e-12 45.1 0.2 1.8e-11 44.2 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFY00519.1 - 9.4e-08 32.1 0.2 1.4e-07 31.5 0.2 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFY00519.1 - 0.0003 20.4 0.3 0.00079 19.1 0.1 1.7 2 0 0 2 2 2 1 KR domain ApbA PF02558.11 KFY00519.1 - 0.0007 19.0 0.2 0.0013 18.1 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KFY00519.1 - 0.0023 17.6 0.7 0.0049 16.5 0.5 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KFY00519.1 - 0.0053 15.8 0.2 0.01 14.9 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 KFY00519.1 - 0.038 14.2 0.5 0.085 13.1 0.3 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding Eno-Rase_NADH_b PF12242.3 KFY00519.1 - 0.076 12.8 2.1 0.16 11.7 1.5 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Thioredoxin_4 PF13462.1 KFY00520.1 - 0.075 13.0 0.0 0.076 13.0 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Glyco_trans_1_3 PF13528.1 KFY00521.1 - 0.026 13.7 0.0 0.062 12.4 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 KFY00521.1 - 0.053 13.1 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain CRAL_TRIO PF00650.15 KFY00522.1 - 1.6e-42 144.6 0.0 3.3e-42 143.6 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFY00522.1 - 1.5e-09 37.8 0.8 3.8e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KFY00522.1 - 4.2e-08 33.2 0.0 8.4e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF3712 PF12505.3 KFY00523.1 - 7.4e-35 119.7 2.5 1.2e-34 119.0 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 KFY00523.1 - 0.076 13.4 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 Late embryogenesis abundant protein FA_hydroxylase PF04116.8 KFY00524.1 - 6.1e-15 55.6 10.1 6.1e-15 55.6 7.0 2.5 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily adh_short PF00106.20 KFY00525.1 - 3.3e-22 79.1 1.9 5.8e-22 78.3 1.3 1.4 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KFY00525.1 - 2.6e-05 24.3 0.3 0.00024 21.1 0.2 2.0 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KFY00525.1 - 3.5e-05 23.5 3.2 0.00036 20.2 2.2 2.0 1 1 0 1 1 1 1 KR domain DFP PF04127.10 KFY00525.1 - 0.0012 18.4 0.7 0.0041 16.7 0.1 1.8 1 1 1 2 2 2 1 DNA / pantothenate metabolism flavoprotein Epimerase PF01370.16 KFY00525.1 - 0.002 17.6 0.1 0.003 17.0 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KFY00525.1 - 0.0027 16.6 0.0 0.0042 16.0 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain UPF0146 PF03686.8 KFY00525.1 - 0.091 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Pyr_redox_3 PF13738.1 KFY00527.1 - 5.3e-29 101.7 0.0 1.4e-27 97.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFY00527.1 - 5.8e-16 57.7 0.0 6.2e-14 51.0 0.0 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KFY00527.1 - 4.7e-11 42.5 0.0 4.1e-09 36.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KFY00527.1 - 1.7e-07 30.5 0.0 0.00015 20.8 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KFY00527.1 - 2.7e-07 29.9 0.1 0.00021 20.4 0.0 2.6 3 0 0 3 3 3 2 Thi4 family Pyr_redox_2 PF07992.9 KFY00527.1 - 2.9e-07 30.5 0.0 0.16 11.7 0.0 3.4 3 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFY00527.1 - 1.2e-06 27.7 0.4 0.0062 15.4 0.1 3.8 3 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KFY00527.1 - 0.00025 20.8 2.5 1.1 8.9 0.1 4.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 KFY00527.1 - 0.00026 21.3 0.1 0.081 13.3 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KFY00527.1 - 0.0014 18.7 0.0 0.22 11.6 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 KFY00527.1 - 0.0018 17.2 0.0 0.47 9.3 0.0 3.5 4 0 0 4 4 4 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KFY00527.1 - 0.0039 16.0 0.1 0.23 10.2 0.3 2.7 2 1 1 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.14 KFY00527.1 - 0.0045 16.0 0.0 9.1 5.2 0.0 3.1 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.17 KFY00527.1 - 0.027 13.3 1.7 2.2 7.0 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.1 KFY00527.1 - 0.12 12.6 0.1 1.9 8.7 0.0 2.8 3 1 0 3 3 3 0 Putative NAD(P)-binding FAD_oxidored PF12831.2 KFY00527.1 - 0.18 10.8 0.1 1.4 7.9 0.0 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase Abhydrolase_5 PF12695.2 KFY00528.1 - 7.8e-12 45.1 0.0 1.5e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFY00528.1 - 5.6e-11 42.7 0.1 1.9e-10 41.0 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 KFY00528.1 - 2.4e-05 23.7 0.0 0.075 12.3 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.6 KFY00528.1 - 0.00029 20.6 0.0 0.00061 19.5 0.0 1.5 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 KFY00528.1 - 0.0057 16.2 0.0 0.0084 15.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KFY00528.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein CRISPR_Cse2 PF09485.5 KFY00528.1 - 0.088 12.8 0.0 3.2 7.7 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Thioesterase PF00975.15 KFY00528.1 - 0.1 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF3715 PF12509.3 KFY00528.1 - 0.12 12.1 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3715) Aldo_ket_red PF00248.16 KFY00529.1 - 4.3e-49 166.8 0.0 3.7e-39 134.2 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family APH PF01636.18 KFY00530.1 - 1.4e-11 44.5 0.0 2.7e-11 43.6 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFY00530.1 - 0.002 17.7 0.0 0.0033 17.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 KFY00530.1 - 0.17 10.9 0.0 0.34 10.0 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Pkinase PF00069.20 KFY00531.1 - 0.036 13.2 0.0 0.1 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain Pkinase_Tyr PF07714.12 KFY00531.1 - 0.12 11.3 0.0 0.33 9.9 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase IBR PF01485.16 KFY00532.1 - 7.5e-10 38.5 45.6 1.2e-06 28.2 4.7 5.2 5 0 0 5 5 5 4 IBR domain zf-C3HC4 PF00097.20 KFY00532.1 - 0.0022 17.6 1.8 0.0022 17.6 1.3 5.2 5 1 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) DAP3 PF10236.4 KFY00535.1 - 2.4e-30 105.5 0.1 3.5e-30 104.9 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 KFY00535.1 - 0.0001 22.3 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 KFY00535.1 - 0.0023 16.8 0.1 0.0025 16.7 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 KFY00535.1 - 0.0051 16.7 0.0 0.0081 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFY00535.1 - 0.046 13.1 0.4 0.071 12.4 0.3 1.3 1 0 0 1 1 1 0 AAA domain PaO PF08417.7 KFY00535.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Pheophorbide a oxygenase RRS1 PF04939.7 KFY00536.1 - 1.7e-56 190.1 2.3 2e-56 189.9 1.6 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) MCM PF00493.18 KFY00537.1 - 5.5e-134 446.1 0.1 1.1e-133 445.2 0.0 1.5 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KFY00537.1 - 1.1e-28 100.1 0.8 3.8e-28 98.3 0.5 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFY00537.1 - 9.4e-08 31.4 0.0 8.7e-06 25.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KFY00537.1 - 4.6e-06 26.4 0.0 1.3e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RecX PF02631.11 KFY00537.1 - 0.013 15.6 1.4 0.11 12.6 0.1 2.4 2 0 0 2 2 2 0 RecX family Mg_chelatase_2 PF13335.1 KFY00537.1 - 0.065 13.6 1.1 0.22 11.9 0.3 2.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Cbl_N PF02262.11 KFY00537.1 - 0.076 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 Glyco_tranf_2_4 PF13704.1 KFY00537.1 - 1.5 9.1 5.2 0.94 9.8 0.0 2.9 3 1 0 3 3 3 0 Glycosyl transferase family 2 Ribosomal_L50 PF10501.4 KFY00550.1 - 2e-21 76.0 0.0 3.7e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S Thiolase_N PF00108.18 KFY00551.1 - 1.9e-73 246.7 1.8 2.8e-73 246.1 1.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Gtr1_RagA PF04670.7 KFY00551.1 - 1.1e-71 240.7 0.1 1.4e-71 240.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Thiolase_C PF02803.13 KFY00551.1 - 2.9e-41 139.7 0.6 7.4e-41 138.4 0.4 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KFY00551.1 - 1.1e-05 25.0 1.4 2.5e-05 23.8 1.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Miro PF08477.8 KFY00551.1 - 0.00053 20.4 0.0 0.0068 16.8 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFY00551.1 - 0.011 14.9 0.0 0.023 13.9 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family ACP_syn_III PF08545.5 KFY00551.1 - 0.059 13.0 1.5 0.5 10.0 0.1 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF1180 PF06679.7 KFY00575.1 - 2 8.2 5.2 3.3 7.5 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) KH_1 PF00013.24 KFY00577.1 - 1.4e-11 43.8 0.0 1.6e-07 30.8 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 KFY00577.1 - 3.5e-06 26.5 2.9 0.00049 19.6 0.0 2.9 3 0 0 3 3 3 2 KH domain DUF566 PF04484.7 KFY00577.1 - 7.5 5.9 8.1 12 5.3 5.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) ALS_ss_C PF10369.4 KFY00578.1 - 2.6e-18 65.5 0.0 4.4e-17 61.5 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 KFY00578.1 - 7.7e-13 47.6 0.1 1.7e-12 46.5 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 KFY00578.1 - 6.9e-10 38.5 0.0 1.2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 ACT domain DUF1949 PF09186.6 KFY00578.1 - 0.071 12.7 0.0 2.5 7.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1949) OGFr_III PF04680.8 KFY00578.1 - 0.13 12.4 0.9 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 Opioid growth factor receptor repeat DUF3712 PF12505.3 KFY00579.1 - 2.9e-07 30.5 4.6 1.6e-05 24.9 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3712) LEA_2 PF03168.8 KFY00579.1 - 5e-05 23.6 3.0 5.8 7.3 0.2 5.0 5 0 0 5 5 5 2 Late embryogenesis abundant protein OTCace_N PF02729.16 KFY00580.1 - 3.6e-44 149.8 0.2 7.2e-44 148.8 0.1 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 KFY00580.1 - 5.1e-39 133.6 0.0 8.1e-39 133.0 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Mpp10 PF04006.7 KFY00581.1 - 2.7e-92 310.0 92.1 2.6e-90 303.5 62.1 2.5 1 1 0 1 1 1 1 Mpp10 protein Oxidored_q6 PF01058.17 KFY00582.1 - 4.1e-22 78.2 0.0 5.8e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Zn_clus PF00172.13 KFY00583.1 - 3.6e-06 26.7 6.2 7.4e-06 25.7 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFY00583.1 - 9e-05 21.4 0.0 0.00019 20.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_L28 PF00830.14 KFY00584.1 - 1.7e-19 69.3 0.4 2.5e-19 68.8 0.3 1.3 1 0 0 1 1 1 1 Ribosomal L28 family SART-1 PF03343.8 KFY00585.1 - 7.4e-167 556.3 69.3 8.5e-167 556.1 48.1 1.0 1 0 0 1 1 1 1 SART-1 family Glyco_hydro_15 PF00723.16 KFY00586.1 - 1.5e-100 336.8 0.0 1.8e-100 336.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 KFY00586.1 - 4.4e-32 109.5 1.0 1.4e-31 107.9 0.7 1.9 1 0 0 1 1 1 1 Starch binding domain CBM_25 PF03423.8 KFY00586.1 - 0.039 14.0 0.9 0.073 13.1 0.0 1.9 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) PITH PF06201.8 KFY00587.1 - 9.3e-47 158.5 0.0 1.1e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 PITH domain PP2C PF00481.16 KFY00588.1 - 2.5e-83 279.3 0.1 3.9e-83 278.7 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KFY00588.1 - 1.2e-05 24.7 0.0 3.3e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C CTP_transf_2 PF01467.21 KFY00589.1 - 3.9e-22 78.9 0.0 6e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase ER_lumen_recept PF00810.13 KFY00591.1 - 1.4e-32 113.2 10.5 1.4e-32 113.2 7.3 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor 7TMR-DISM_7TM PF07695.6 KFY00591.1 - 0.13 11.9 12.4 0.036 13.7 6.5 1.6 1 1 0 1 1 1 0 7TM diverse intracellular signalling PQ-loop PF04193.9 KFY00591.1 - 0.14 11.7 7.6 0.23 11.0 0.0 2.8 3 0 0 3 3 3 0 PQ loop repeat HlyIII PF03006.15 KFY00591.1 - 0.95 8.8 11.9 1.3 8.3 1.8 2.3 1 1 1 2 2 2 0 Haemolysin-III related DUF1751 PF08551.5 KFY00591.1 - 1.2 9.4 6.4 0.74 10.1 0.6 2.6 1 1 2 3 3 3 0 Eukaryotic integral membrane protein (DUF1751) DSPc PF00782.15 KFY00597.1 - 3.4e-20 72.0 0.0 4.1e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFY00597.1 - 0.00066 19.0 0.0 0.00078 18.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 KFY00597.1 - 0.074 11.8 0.0 0.097 11.5 0.0 1.2 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Y_phosphatase3 PF13350.1 KFY00597.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.3 1 1 0 1 1 1 0 Tyrosine phosphatase family Peptidase_S64 PF08192.6 KFY00598.1 - 0.0067 14.8 0.1 0.0076 14.6 0.1 1.0 1 0 0 1 1 1 1 Peptidase family S64 Peptidase_S32 PF05579.8 KFY00598.1 - 0.025 13.5 0.1 0.026 13.4 0.1 1.0 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 PTPA PF03095.10 KFY00599.1 - 3e-98 328.6 0.0 3.7e-98 328.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Spc7 PF08317.6 KFY00601.1 - 0.0012 17.5 13.8 0.0012 17.5 9.5 8.1 1 1 6 8 8 8 4 Spc7 kinetochore protein Filament PF00038.16 KFY00601.1 - 0.13 11.6 133.2 0.36 10.2 23.5 5.6 1 1 4 5 5 5 0 Intermediate filament protein Shugoshin_N PF07558.6 KFY00601.1 - 1.5 8.5 6.8 4.3 7.1 0.1 5.0 7 0 0 7 7 7 0 Shugoshin N-terminal coiled-coil region ATG16 PF08614.6 KFY00602.1 - 0.011 15.6 2.7 0.011 15.6 1.8 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.1 KFY00602.1 - 0.041 12.3 4.5 0.057 11.8 3.1 1.1 1 0 0 1 1 1 0 AAA domain IL34 PF15036.1 KFY00602.1 - 0.054 13.0 0.1 0.18 11.3 0.0 1.8 1 1 1 2 2 2 0 Interleukin 34 NPV_P10 PF05531.7 KFY00602.1 - 0.11 12.8 4.4 5.6 7.2 0.4 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CENP-F_leu_zip PF10473.4 KFY00602.1 - 0.17 11.7 4.1 6 6.7 0.0 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tht1 PF04163.7 KFY00602.1 - 0.34 9.2 5.7 0.98 7.7 3.9 2.0 1 1 0 1 1 1 0 Tht1-like nuclear fusion protein DUF3510 PF12022.3 KFY00602.1 - 0.53 10.3 5.0 14 5.8 0.9 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF3510) MitMem_reg PF13012.1 KFY00602.1 - 0.73 9.9 5.0 1.4 9.0 1.8 2.3 1 1 0 2 2 2 0 Maintenance of mitochondrial structure and function Reo_sigmaC PF04582.7 KFY00602.1 - 2.4 7.2 11.8 0.37 9.9 0.9 2.2 1 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF1664 PF07889.7 KFY00602.1 - 9.5 6.0 10.5 3.3 7.5 1.1 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Ribosomal_L6 PF00347.18 KFY00603.1 - 2.6e-24 85.5 0.1 3.8e-13 49.7 0.0 3.0 3 0 0 3 3 3 2 Ribosomal protein L6 Inositol_P PF00459.20 KFY00604.1 - 1.6e-53 181.7 1.7 3e-53 180.8 1.2 1.3 1 1 0 1 1 1 1 Inositol monophosphatase family zf-C3HC PF07967.8 KFY00605.1 - 1e-32 112.6 0.0 6.3e-31 106.9 0.0 2.4 2 0 0 2 2 2 1 C3HC zinc finger-like Rsm1 PF08600.5 KFY00605.1 - 8.9e-18 63.9 2.0 1.3e-15 56.9 0.0 2.9 2 1 0 2 2 2 2 Rsm1-like BIR PF00653.16 KFY00605.1 - 0.0045 17.3 0.3 0.07 13.5 0.1 2.4 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain DM PF00751.13 KFY00605.1 - 0.069 12.6 0.0 4.5 6.8 0.0 2.5 2 0 0 2 2 2 0 DM DNA binding domain Zip PF02535.17 KFY00606.1 - 0.0074 15.3 0.3 0.0074 15.3 0.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter NicO PF03824.11 KFY00606.1 - 0.0086 15.4 3.4 0.01 15.1 2.4 1.1 1 0 0 1 1 1 1 High-affinity nickel-transport protein AA_permease PF00324.16 KFY00608.1 - 3.7e-99 332.2 36.9 4.5e-99 331.9 25.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFY00608.1 - 2.7e-21 75.5 37.8 4.5e-21 74.8 26.2 1.4 1 0 0 1 1 1 1 Amino acid permease DUF3487 PF11990.3 KFY00608.1 - 4.7 6.6 7.5 1.3 8.4 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF1772 PF08592.6 KFY00608.1 - 9.7 5.9 12.3 3.3 7.4 2.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) PEX11 PF05648.9 KFY00609.1 - 2.8e-26 92.1 0.0 3.2e-26 91.9 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Peptidase_M20 PF01546.23 KFY00610.1 - 7.2e-25 87.5 0.0 9.9e-25 87.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFY00610.1 - 5.9e-11 42.1 0.0 1e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KFY00610.1 - 0.027 14.2 0.0 0.063 13.0 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M28 Peptidase_M24 PF00557.19 KFY00611.1 - 1.9e-20 73.3 0.1 2.8e-20 72.7 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KFY00611.1 - 7.1e-16 58.8 0.0 1.3e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Snurportin1 PF11538.3 KFY00611.1 - 0.11 12.2 0.6 0.3 10.8 0.4 1.7 1 0 0 1 1 1 0 Snurportin1 Beta_elim_lyase PF01212.16 KFY00612.1 - 1.4e-77 260.7 0.0 2.6e-77 259.8 0.0 1.4 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 KFY00612.1 - 0.00027 20.0 0.1 0.00089 18.3 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KFY00612.1 - 0.0011 17.2 0.0 0.0016 16.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aldedh PF00171.17 KFY00613.1 - 3.6e-184 612.4 0.3 4e-184 612.2 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_32C PF08244.7 KFY00614.1 - 6.6e-19 68.0 0.4 1.2e-18 67.2 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.15 KFY00614.1 - 4.5e-14 52.5 0.0 7.6e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Diacid_rec PF05651.8 KFY00614.1 - 0.042 13.2 0.0 0.091 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative sugar diacid recognition Pkinase PF00069.20 KFY00615.1 - 7.9e-43 146.4 0.0 7.9e-42 143.1 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY00615.1 - 4.2e-25 88.2 0.0 1.2e-24 86.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Ribosomal_S4 PF00163.14 KFY00616.1 - 5.4e-14 52.3 0.1 9.7e-14 51.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KFY00616.1 - 1.5e-11 43.4 0.0 2.9e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain Clr5 PF14420.1 KFY00617.1 - 2.1e-06 27.5 2.2 3.8e-06 26.7 1.6 1.5 1 0 0 1 1 1 1 Clr5 domain His_kinase PF06580.8 KFY00617.1 - 0.069 13.0 0.2 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Histidine kinase Glyco_hydro_3 PF00933.16 KFY00618.1 - 1.3e-59 201.6 0.0 1.8e-59 201.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFY00618.1 - 8e-44 149.8 0.0 1.4e-43 149.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFY00618.1 - 1.5e-07 31.2 0.0 3.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain FAD_binding_4 PF01565.18 KFY00620.1 - 3.8e-23 81.5 4.4 7.7e-23 80.5 3.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFY00620.1 - 0.0002 21.1 0.0 0.00043 20.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.11 KFY00621.1 - 5.2e-28 97.7 19.2 5.2e-28 97.7 13.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3792 PF12670.2 KFY00621.1 - 2.5 8.0 10.7 0.062 13.1 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3792) TauD PF02668.11 KFY00622.1 - 5.3e-47 160.6 0.1 1e-46 159.7 0.1 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fungal_trans_2 PF11951.3 KFY00623.1 - 8.8e-53 179.2 0.0 1.6e-52 178.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KFY00623.1 - 2.9e-07 30.4 12.0 0.003 17.7 0.7 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.13 KFY00623.1 - 4.3e-06 26.5 21.7 4.7e-05 23.1 6.1 3.3 4 0 0 4 4 4 2 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 KFY00623.1 - 0.00014 21.9 13.6 0.015 15.5 0.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFY00623.1 - 0.00022 21.3 3.0 0.00022 21.3 2.1 4.7 4 1 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.2 KFY00623.1 - 0.035 14.3 3.2 6.9 7.0 0.2 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFY00623.1 - 0.93 9.7 5.1 16 5.8 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFY00623.1 - 3.8 7.5 7.1 1.1 9.2 0.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Glyco_hydro_3 PF00933.16 KFY00624.1 - 1.5e-64 217.8 0.0 2.1e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFY00624.1 - 1.4e-43 149.0 0.0 2e-43 148.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain WSC PF01822.14 KFY00624.1 - 6.9e-16 57.9 9.8 1.5e-15 56.8 6.8 1.6 1 0 0 1 1 1 1 WSC domain Amidohydro_1 PF01979.15 KFY00625.1 - 2.1e-56 191.9 0.2 2.6e-56 191.6 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KFY00625.1 - 1.2e-14 55.0 0.1 5.3e-10 39.7 0.0 2.6 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 KFY00625.1 - 4.7e-13 49.1 0.1 5.1e-12 45.7 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 KFY00625.1 - 2.5e-08 33.5 0.0 6.4e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 KFY00625.1 - 0.00051 19.0 0.0 0.0015 17.5 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase Xan_ur_permease PF00860.15 KFY00626.1 - 2.4e-70 237.0 34.0 4.7e-69 232.7 23.5 2.1 1 1 0 1 1 1 1 Permease family ABC2_membrane PF01061.19 KFY00627.1 - 2.5e-29 101.9 30.1 3.7e-29 101.3 20.9 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 KFY00627.1 - 6e-26 91.3 0.0 9e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFY00627.1 - 8e-07 29.3 0.1 0.0048 16.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KFY00627.1 - 7.8e-06 25.4 0.1 0.00025 20.4 0.1 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KFY00627.1 - 3e-05 23.2 0.1 5.6e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFY00627.1 - 9.1e-05 22.5 0.1 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFY00627.1 - 0.0027 17.8 0.1 0.01 15.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFY00627.1 - 0.0051 16.5 0.4 0.012 15.3 0.2 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 KFY00627.1 - 0.0069 16.3 0.1 0.014 15.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KFY00627.1 - 0.0082 16.3 0.1 0.034 14.3 0.1 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KFY00627.1 - 0.01 14.5 0.0 0.015 14.0 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein IstB_IS21 PF01695.12 KFY00627.1 - 0.013 14.9 0.1 0.03 13.7 0.0 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein SMC_N PF02463.14 KFY00627.1 - 0.014 14.6 0.0 0.058 12.6 0.0 1.8 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KFY00627.1 - 0.029 14.3 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.1 KFY00627.1 - 0.031 15.1 0.1 0.074 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 KFY00627.1 - 0.035 13.1 0.0 0.37 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 KFY00627.1 - 0.04 12.8 0.0 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 KFY00627.1 - 0.04 13.5 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 KFY00627.1 - 0.045 13.2 0.0 0.099 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 KFY00627.1 - 0.058 13.2 0.0 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KFY00627.1 - 0.059 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 KFY00627.1 - 0.061 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 KFY00627.1 - 0.091 13.0 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KFY00627.1 - 0.092 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 KFY00627.1 - 0.097 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KFY00627.1 - 0.1 12.1 0.5 0.17 11.4 0.3 1.3 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KFY00627.1 - 0.11 12.4 0.0 0.31 11.0 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.4 KFY00627.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 KFY00627.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 KFY00628.1 - 1.4e-05 24.1 0.0 2.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 KFY00629.1 - 3.3e-16 59.6 0.0 4.8e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.5 KFY00629.1 - 2.3e-06 26.9 0.2 2.7e-06 26.7 0.2 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 KFY00629.1 - 0.025 14.2 0.1 0.06 13.0 0.0 1.7 1 1 0 1 1 1 0 KR domain GST_N_3 PF13417.1 KFY00630.1 - 2.6e-10 40.3 0.0 5.4e-10 39.3 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFY00630.1 - 6.1e-07 29.3 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KFY00630.1 - 0.033 14.6 0.0 0.17 12.4 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain p450 PF00067.17 KFY00631.1 - 1.2e-78 264.7 0.0 1.3e-78 264.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MyTH4 PF00784.12 KFY00631.1 - 0.029 14.3 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 MyTH4 domain MFS_1 PF07690.11 KFY00632.1 - 3e-14 52.5 37.5 3e-14 52.5 26.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily PRKCSH-like PF12999.2 KFY00633.1 - 1.2e-45 155.2 1.5 5.7e-25 87.8 0.1 2.9 2 0 0 2 2 2 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 KFY00633.1 - 2.7e-30 104.8 3.4 3.8e-30 104.3 0.6 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 KFY00633.1 - 1.4e-09 38.5 0.5 1.4e-09 38.5 0.4 2.0 2 0 0 2 2 1 1 Glucosidase II beta subunit-like protein DUF3837 PF12939.2 KFY00633.1 - 0.036 14.0 0.0 0.085 12.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) Lyase_8_N PF08124.6 KFY00633.1 - 0.083 11.7 0.1 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain GldM_N PF12081.3 KFY00633.1 - 0.11 11.9 3.6 0.22 11.0 2.5 1.4 1 0 0 1 1 1 0 GldM N-terminal domain DUF2514 PF10721.4 KFY00633.1 - 1.1 8.9 10.6 4.1 7.0 7.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) DUF4407 PF14362.1 KFY00633.1 - 1.5 7.7 6.0 2.5 6.9 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ldl_recept_a PF00057.13 KFY00633.1 - 1.7 8.6 9.1 0.97 9.3 0.8 2.8 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A DUF972 PF06156.8 KFY00633.1 - 1.8 8.9 6.1 11 6.4 1.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 KFY00633.1 - 2.1 7.9 9.3 4.7 6.7 6.5 1.5 1 0 0 1 1 1 0 IncA protein Spc24 PF08286.6 KFY00633.1 - 3.2 7.4 7.6 0.44 10.2 2.0 2.0 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Fe-S_biosyn PF01521.15 KFY00634.1 - 4.8e-15 55.4 0.0 1.3e-13 50.8 0.0 2.1 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Ribosomal_L30_N PF08079.7 KFY00635.1 - 2.4e-24 85.1 19.7 2.4e-24 85.1 13.7 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 KFY00635.1 - 1.5e-18 66.1 1.4 1.5e-18 66.1 1.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Trypan_PARP PF05887.6 KFY00636.1 - 0.27 11.0 19.8 0.35 10.6 13.7 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CENP-T PF15511.1 KFY00636.1 - 0.6 9.2 12.7 0.67 9.1 8.8 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Pkinase PF00069.20 KFY00637.1 - 1.3e-70 237.5 0.0 1.8e-70 237.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY00637.1 - 1.4e-30 106.2 0.0 2.1e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KFY00637.1 - 7.9e-14 51.9 0.3 3.1e-13 50.0 0.2 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFY00637.1 - 8.2e-09 34.8 0.0 1.5e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like C2 PF00168.25 KFY00637.1 - 1.6e-06 27.8 0.0 6.3e-06 25.9 0.0 2.1 1 1 0 1 1 1 1 C2 domain APH PF01636.18 KFY00637.1 - 0.05 13.3 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFY00637.1 - 0.1 12.1 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase ATP_sub_h PF10775.4 KFY00638.1 - 6.6e-26 89.8 1.3 9.2e-26 89.3 0.9 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 KFY00638.1 - 0.00066 19.5 0.2 0.00083 19.2 0.2 1.3 1 1 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 TFIIB PF00382.14 KFY00639.1 - 1.6e-33 114.2 0.0 7.4e-18 64.1 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 KFY00639.1 - 4.8e-14 51.4 1.4 7.7e-14 50.7 1.0 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 KFY00639.1 - 0.028 14.3 0.0 3 7.7 0.0 2.3 1 1 0 2 2 2 0 Cyclin, C-terminal domain Sigma70_r4 PF04545.11 KFY00639.1 - 0.03 13.6 0.0 0.1 11.9 0.0 1.9 1 0 0 1 1 1 0 Sigma-70, region 4 zf-ribbon_3 PF13248.1 KFY00639.1 - 0.16 11.2 1.1 0.33 10.2 0.4 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Sugar_tr PF00083.19 KFY00640.1 - 6.4e-67 226.0 27.3 8.4e-67 225.6 19.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY00640.1 - 1e-18 67.2 29.1 1e-18 67.2 20.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFY00640.1 - 1.6e-06 26.7 27.3 1.4e-05 23.6 2.7 3.4 2 1 0 3 3 3 3 MFS/sugar transport protein Ras PF00071.17 KFY00643.1 - 2.1e-40 137.7 0.0 2.3e-38 131.1 0.0 2.1 2 0 0 2 2 2 1 Ras family Miro PF08477.8 KFY00643.1 - 3.8e-17 62.8 0.0 5.2e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFY00643.1 - 1.4e-10 40.6 0.0 2.5e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFY00643.1 - 2.5e-05 23.5 0.0 3.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 KFY00643.1 - 0.011 15.7 0.1 0.037 14.0 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.5 KFY00643.1 - 0.027 13.7 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KFY00643.1 - 0.031 14.2 0.0 0.061 13.2 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 KFY00643.1 - 0.032 14.3 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 KFY00643.1 - 0.041 13.7 0.0 0.063 13.1 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_24 PF13479.1 KFY00643.1 - 0.057 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFY00643.1 - 0.071 12.9 0.3 0.12 12.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KFY00643.1 - 0.075 13.0 0.5 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KFY00643.1 - 0.089 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Peptidase_S41 PF03572.13 KFY00645.1 - 2.7e-07 30.1 0.0 7e-07 28.8 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 Abhydrolase_3 PF07859.8 KFY00646.1 - 3.5e-40 137.8 0.0 4.3e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFY00646.1 - 1.2e-10 41.6 0.6 4.2e-10 39.8 0.4 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFY00646.1 - 7.3e-07 29.0 0.0 8.6e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_9 PF10081.4 KFY00646.1 - 0.051 12.2 0.0 0.078 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family COesterase PF00135.23 KFY00646.1 - 0.2 10.3 0.0 0.61 8.7 0.0 1.7 2 0 0 2 2 2 0 Carboxylesterase family Robl_LC7 PF03259.12 KFY00648.1 - 3.4e-07 29.7 0.0 2.2e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain Ipi1_N PF12333.3 KFY00649.1 - 1e-23 83.2 0.0 3.2e-22 78.4 0.0 2.9 2 1 1 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation DUF262 PF03235.9 KFY00649.1 - 3.4e-17 63.1 0.1 1.9e-16 60.7 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function DUF262 DASH_Hsk3 PF08227.6 KFY00650.1 - 2e-12 47.0 0.0 3.9e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like p450 PF00067.17 KFY00651.1 - 4e-31 108.0 0.0 7.2e-31 107.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Ctr PF04145.10 KFY00652.1 - 1.1e-31 109.7 0.1 1.9e-31 109.0 0.1 1.4 1 0 0 1 1 1 1 Ctr copper transporter family ProRS-C_1 PF09180.6 KFY00652.1 - 0.058 13.3 0.5 0.12 12.2 0.4 1.6 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal Malate_synthase PF01274.17 KFY00653.1 - 1.7e-233 775.3 0.0 2e-233 775.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Rpr2 PF04032.11 KFY00654.1 - 3e-23 81.4 1.5 1e-22 79.7 1.0 1.9 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_3 PF13878.1 KFY00654.1 - 2.1 7.9 5.1 3.4 7.3 0.2 2.6 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO DEAD PF00270.24 KFY00655.1 - 9.8e-37 126.0 0.2 1.6e-36 125.3 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFY00655.1 - 1.2e-24 85.9 0.0 8.7e-23 79.9 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFY00655.1 - 1.1e-07 31.9 0.0 2.4e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pkinase PF00069.20 KFY00676.1 - 2.9e-70 236.3 0.0 4.7e-70 235.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY00676.1 - 2e-44 151.5 0.0 3.5e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 KFY00676.1 - 2.7e-20 72.5 0.0 2.7e-20 72.5 0.0 3.0 3 0 0 3 3 3 1 P21-Rho-binding domain Kinase-like PF14531.1 KFY00676.1 - 3.2e-07 29.5 0.0 5.8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFY00676.1 - 0.05 13.3 0.0 0.15 11.8 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family SP2 PF03014.9 KFY00677.1 - 0.088 10.6 0.1 0.098 10.5 0.0 1.0 1 0 0 1 1 1 0 Structural protein 2 SAYSvFN PF10260.4 KFY00680.1 - 0.012 15.4 1.3 1.7 8.4 0.0 3.3 3 1 0 3 3 3 0 Uncharacterized conserved domain (SAYSvFN) Enhancin PF03272.8 KFY00680.1 - 0.061 11.2 0.0 0.071 11.0 0.0 1.0 1 0 0 1 1 1 0 Viral enhancin protein Pep_M12B_propep PF01562.14 KFY00680.1 - 0.14 11.9 0.0 0.53 10.0 0.0 1.8 2 0 0 2 2 2 0 Reprolysin family propeptide Antig_Caf1 PF09255.5 KFY00680.1 - 0.64 9.9 3.7 4.4 7.1 0.3 2.1 1 1 1 2 2 2 0 Caf1 Capsule antigen Chromo PF00385.19 KFY00682.1 - 1.3e-10 40.7 0.2 1.3e-10 40.7 0.1 2.4 2 1 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 KFY00682.1 - 5.8e-07 29.2 0.0 3e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 Chromo shadow domain DUF3022 PF11226.3 KFY00682.1 - 0.019 14.8 0.1 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3022) MTHFR PF02219.12 KFY00682.1 - 0.082 11.9 0.2 6.5 5.7 0.0 2.1 2 0 0 2 2 2 0 Methylenetetrahydrofolate reductase Thioredoxin_8 PF13905.1 KFY00682.1 - 0.087 12.9 0.0 0.36 10.9 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like Myc_N PF01056.13 KFY00682.1 - 2 7.5 8.9 1.6 7.8 4.3 2.0 2 0 0 2 2 2 0 Myc amino-terminal region DUF21 PF01595.15 KFY00684.1 - 9.8e-26 90.1 0.3 2.9e-25 88.6 0.2 1.7 1 1 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KFY00684.1 - 5.6e-08 32.4 0.1 0.0045 16.7 0.0 2.7 2 0 0 2 2 2 2 CBS domain DUF2434 PF10361.4 KFY00684.1 - 0.038 13.0 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2434) Flavoprotein PF02441.14 KFY00685.1 - 8.4e-16 57.8 0.0 2e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Flavoprotein zf-DHHC PF01529.15 KFY00686.1 - 6.9e-27 93.9 4.5 6.9e-27 93.9 3.1 1.8 3 0 0 3 3 3 1 DHHC palmitoyltransferase DUF1418 PF07214.7 KFY00686.1 - 0.52 9.9 6.0 0.094 12.3 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) YrhC PF14143.1 KFY00686.1 - 1.1 9.3 8.1 0.07 13.0 1.6 1.9 2 0 0 2 2 2 0 YrhC-like protein Myb_DNA-bind_2 PF08914.6 KFY00687.1 - 4e-16 58.5 0.7 1.5e-15 56.7 0.1 2.4 2 0 0 2 2 2 1 Rap1 Myb domain Rap1_C PF11626.3 KFY00687.1 - 8.5e-15 54.4 0.3 2.3e-14 53.0 0.2 1.7 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain ARID PF01388.16 KFY00687.1 - 1.1e-13 50.7 0.0 1.7e-07 31.0 0.0 2.7 2 0 0 2 2 2 2 ARID/BRIGHT DNA binding domain Rap1-DNA-bind PF09197.5 KFY00687.1 - 4e-05 24.1 2.9 0.00014 22.3 0.0 3.2 4 0 0 4 4 4 1 Rap1, DNA-binding VHS PF00790.14 KFY00689.1 - 7.2e-24 84.0 0.0 1.8e-23 82.7 0.0 1.7 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 KFY00689.1 - 3e-10 39.9 1.5 7.7e-10 38.6 1.0 1.7 1 0 0 1 1 1 1 GAT domain DUF3275 PF11679.3 KFY00689.1 - 4.5 6.8 6.2 0.87 9.1 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) KH_1 PF00013.24 KFY00694.1 - 4.2e-73 240.9 18.8 3.9e-12 45.6 0.1 10.5 10 1 0 10 10 10 8 KH domain KH_3 PF13014.1 KFY00694.1 - 3.1e-50 167.0 21.0 1e-09 37.8 0.0 10.8 12 0 0 12 12 12 7 KH domain KH_2 PF07650.12 KFY00694.1 - 2.6e-11 42.9 20.9 0.025 14.1 0.0 6.8 4 2 1 6 6 6 4 KH domain SLS PF14611.1 KFY00694.1 - 4.5e-10 39.3 1.6 0.0034 16.8 0.0 6.1 5 2 2 7 7 7 3 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.1 KFY00694.1 - 2.5e-05 23.8 7.4 0.54 9.9 0.1 5.4 5 0 0 5 5 5 2 KH domain KH_5 PF13184.1 KFY00694.1 - 0.0016 18.2 3.7 16 5.4 0.0 5.5 5 0 0 5 5 5 2 NusA-like KH domain DnaJ-X PF14308.1 KFY00697.1 - 7.8e-71 237.5 1.9 7.8e-71 237.5 1.3 2.1 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 KFY00697.1 - 1e-24 86.0 0.4 2.3e-24 84.9 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain RmlD_sub_bind PF04321.12 KFY00697.1 - 1.6e-13 50.2 0.0 4e-13 48.9 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 KFY00697.1 - 1.8e-11 43.9 0.0 3.6e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KFY00697.1 - 6.3e-05 22.0 0.2 0.00086 18.2 0.0 2.6 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein Macro PF01661.16 KFY00697.1 - 0.06 13.2 0.0 0.25 11.2 0.0 2.1 1 0 0 1 1 1 0 Macro domain adh_short PF00106.20 KFY00697.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 short chain dehydrogenase Cyt-b5 PF00173.23 KFY00699.1 - 9.5e-16 57.3 0.0 1.5e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FHA PF00498.21 KFY00700.1 - 3.1e-08 33.6 0.1 7.3e-08 32.4 0.1 1.7 1 0 0 1 1 1 1 FHA domain BRCT PF00533.21 KFY00700.1 - 0.0015 18.6 0.4 0.025 14.7 0.1 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain TRM PF02005.11 KFY00701.1 - 5.3e-107 357.9 0.0 3e-93 312.7 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 KFY00701.1 - 0.042 13.4 0.0 0.097 12.2 0.0 1.6 1 0 0 1 1 1 0 Met-10+ like-protein Inositol_P PF00459.20 KFY00702.1 - 2e-66 224.0 0.0 2.2e-66 223.9 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF1134 PF06577.7 KFY00702.1 - 0.043 13.3 0.1 0.083 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1134) Antimicrobial_9 PF08104.6 KFY00702.1 - 0.075 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Ponericin L family U79_P34 PF03064.11 KFY00703.1 - 0.014 14.9 2.7 0.014 14.9 1.9 2.4 3 0 0 3 3 3 0 HSV U79 / HCMV P34 SMC_Nse1 PF07574.8 KFY00704.1 - 2.2e-39 135.1 0.0 2.7e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 KFY00704.1 - 5e-14 52.0 7.5 9e-14 51.2 5.2 1.4 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.1 KFY00704.1 - 0.49 10.2 11.6 0.031 14.0 4.5 1.7 2 0 0 2 2 2 0 Ring finger domain FANCL_C PF11793.3 KFY00704.1 - 0.89 9.5 5.2 2.9 7.9 3.6 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain DUF500 PF04366.7 KFY00705.1 - 8.6e-42 141.5 0.1 1.5e-41 140.7 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) WD40 PF00400.27 KFY00706.1 - 7.7e-14 50.9 10.1 3.2e-05 23.6 0.0 7.3 8 0 0 8 8 8 5 WD domain, G-beta repeat SPRY PF00622.23 KFY00706.1 - 1.7e-09 37.7 0.1 2.6e-08 34.0 0.0 2.8 4 0 0 4 4 4 1 SPRY domain Clr5 PF14420.1 KFY00707.1 - 0.12 12.2 0.0 0.18 11.7 0.0 1.3 1 1 0 1 1 1 0 Clr5 domain SQS_PSY PF00494.14 KFY00708.1 - 4e-38 131.2 0.0 5.8e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase UAF_Rrn10 PF05234.6 KFY00710.1 - 0.00037 20.5 0.0 0.00052 20.0 0.0 1.2 1 0 0 1 1 1 1 UAF complex subunit Rrn10 WD40 PF00400.27 KFY00711.1 - 3e-33 112.4 13.3 2.4e-10 39.8 0.2 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 KFY00711.1 - 0.0087 14.2 0.3 0.49 8.4 0.1 2.8 2 1 0 2 2 2 2 Nucleoporin Nup120/160 TFIIIC_delta PF12657.2 KFY00711.1 - 0.027 14.1 0.2 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Transcription factor IIIC subunit delta N-term Ribosomal_L44 PF00935.14 KFY00714.1 - 4.7e-35 119.4 11.7 1.1e-34 118.2 8.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L44 DUF2652 PF10851.3 KFY00714.1 - 2 8.4 5.2 0.43 10.5 1.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2652) p450 PF00067.17 KFY00715.1 - 3.9e-45 154.2 0.0 1.1e-44 152.8 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Chromo PF00385.19 KFY00724.1 - 0.013 15.2 2.6 0.013 15.2 1.8 2.0 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain ORC6 PF05460.8 KFY00725.1 - 0.59 9.1 5.6 0.81 8.7 3.9 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Erv26 PF04148.8 KFY00726.1 - 3.4e-81 271.6 2.3 4e-81 271.4 1.6 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Methyltransf_11 PF08241.7 KFY00727.1 - 3.6e-10 40.1 0.0 7.6e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain WBS_methylT PF12589.3 KFY00727.1 - 4.7e-10 39.8 2.8 9.2e-10 38.8 1.9 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.1 KFY00727.1 - 4.6e-06 26.9 0.0 1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY00727.1 - 2.2e-05 24.1 0.0 3.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY00727.1 - 5.9e-05 23.4 0.2 0.00044 20.6 0.0 2.5 3 1 0 3 3 3 1 Methyltransferase domain PCMT PF01135.14 KFY00727.1 - 0.0001 21.8 0.0 0.00021 20.8 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 KFY00727.1 - 0.00022 20.9 0.0 0.00035 20.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY00727.1 - 0.00022 21.7 0.0 0.00043 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KFY00727.1 - 0.00068 18.8 0.0 0.0014 17.7 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 KFY00727.1 - 0.0083 16.1 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFY00727.1 - 0.0099 15.0 0.0 0.027 13.6 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family DUF1640 PF07798.6 KFY00728.1 - 1.2e-60 204.6 9.6 1.5e-60 204.2 6.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) OEP PF02321.13 KFY00728.1 - 0.27 10.8 7.6 2.8 7.4 0.3 2.3 1 1 1 2 2 2 0 Outer membrane efflux protein cwf21 PF08312.7 KFY00728.1 - 0.37 10.6 5.5 0.52 10.2 2.7 2.1 2 1 0 2 2 2 0 cwf21 domain Syntaxin PF00804.20 KFY00728.1 - 0.72 10.0 8.1 1.4 9.1 5.0 2.0 1 1 0 1 1 1 0 Syntaxin GTP_EFTU PF00009.22 KFY00729.1 - 1.3e-37 129.0 0.0 2.1e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 KFY00729.1 - 1.1e-36 124.6 0.4 2.6e-36 123.5 0.2 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 KFY00729.1 - 2e-10 40.6 0.5 4.1e-10 39.6 0.4 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFY00729.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Rho_N PF07498.7 KFY00730.1 - 4.4e-05 23.1 0.1 0.3 10.8 0.0 3.4 3 0 0 3 3 3 2 Rho termination factor, N-terminal domain Bystin PF05291.6 KFY00731.1 - 2.3e-125 417.5 0.0 3.1e-125 417.1 0.0 1.1 1 0 0 1 1 1 1 Bystin bZIP_1 PF00170.16 KFY00733.1 - 6.1e-05 22.9 6.6 0.0001 22.2 4.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFY00733.1 - 0.0015 18.3 6.9 0.0024 17.6 4.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFY00733.1 - 0.017 15.4 1.6 0.028 14.6 1.1 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor Mei5 PF10376.4 KFY00733.1 - 0.25 10.8 2.8 0.33 10.4 1.9 1.1 1 0 0 1 1 1 0 Double-strand recombination repair protein CcmD PF04995.9 KFY00733.1 - 7.1 6.4 9.0 25 4.7 0.0 3.0 2 1 1 3 3 3 0 Heme exporter protein D (CcmD) Zn_clus PF00172.13 KFY00734.1 - 6e-08 32.4 10.8 6e-08 32.4 7.5 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFY00734.1 - 1.4e-07 30.4 8.9 2.5e-07 29.6 6.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 KFY00736.1 - 1.1e-44 152.7 0.0 2.2e-44 151.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF3425 PF11905.3 KFY00737.1 - 2.8e-13 49.9 0.3 8e-13 48.4 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KFY00737.1 - 0.0002 21.2 14.5 0.0009 19.1 10.0 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFY00737.1 - 0.34 10.7 17.4 19 5.1 12.1 2.2 1 1 0 1 1 1 0 Basic region leucine zipper Glyco_hydro_16 PF00722.16 KFY00738.1 - 1.6e-41 141.6 3.0 1.6e-41 141.6 2.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 PIH1 PF08190.7 KFY00738.1 - 5.8 6.2 7.7 8.3 5.7 5.3 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Pneumo_att_G PF05539.6 KFY00738.1 - 9 5.5 24.7 15 4.8 17.1 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DUF1771 PF08590.5 KFY00744.1 - 2.2e-21 75.6 11.8 3.9e-21 74.8 8.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 KFY00744.1 - 2.4e-16 59.6 0.1 6e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Smr domain adh_short PF00106.20 KFY00746.1 - 2.2e-13 50.4 0.0 3.5e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFY00746.1 - 3.9e-06 26.6 0.0 6.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFY00746.1 - 0.00074 19.3 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.13 KFY00746.1 - 0.0024 17.8 0.3 0.0058 16.6 0.1 1.7 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_10 PF13460.1 KFY00746.1 - 0.0057 16.6 0.0 0.035 14.0 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KFY00746.1 - 0.0072 15.6 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KFY00746.1 - 0.021 13.7 0.0 1.2 8.0 0.0 2.4 2 1 0 2 2 2 0 Male sterility protein Epimerase PF01370.16 KFY00746.1 - 0.028 13.8 0.1 0.044 13.2 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans_2 PF11951.3 KFY00747.1 - 6.5e-36 123.7 3.5 9.1e-36 123.2 2.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY00747.1 - 4.9e-07 29.5 8.8 8.7e-07 28.7 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Melibiase PF02065.13 KFY00748.1 - 5.3e-156 519.2 0.0 7.7e-156 518.7 0.0 1.2 1 0 0 1 1 1 1 Melibiase DUF187 PF02638.10 KFY00748.1 - 7.8e-06 24.9 0.0 1.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 Clr5 PF14420.1 KFY00750.1 - 9.3e-11 41.4 0.1 2.4e-10 40.1 0.1 1.7 1 0 0 1 1 1 1 Clr5 domain DUF1720 PF08226.6 KFY00750.1 - 0.0058 16.6 1.4 0.23 11.5 0.0 2.6 1 1 1 2 2 2 1 Domain of unknown function (DUF1720) Orn_Arg_deC_N PF02784.11 KFY00751.1 - 3.7e-76 255.6 0.0 5e-76 255.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KFY00751.1 - 1e-30 105.7 0.1 1.8e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 KFY00751.1 - 0.063 12.5 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel M16C_assoc PF08367.6 KFY00752.1 - 1.1e-59 201.3 0.1 1.6e-59 200.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 KFY00752.1 - 5.5e-37 127.2 0.1 2.1e-21 76.4 0.0 3.7 5 0 0 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KFY00752.1 - 1.9e-08 34.2 0.1 1e-07 31.8 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Taxilin PF09728.4 KFY00753.1 - 6.4e-93 311.2 58.8 8.6e-93 310.7 40.7 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Histone_HNS PF00816.16 KFY00754.1 - 0.032 14.7 0.9 0.1 13.0 0.7 1.9 1 0 0 1 1 1 0 H-NS histone family DUF4120 PF13496.1 KFY00754.1 - 0.15 12.1 0.0 0.41 10.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4120) NMO PF03060.10 KFY00755.1 - 5.5e-72 242.6 3.1 6.3e-72 242.4 2.2 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KFY00755.1 - 2e-05 23.6 2.2 3e-05 23.0 0.7 1.8 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KFY00755.1 - 0.011 14.5 5.3 0.019 13.8 3.7 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase CTP_transf_1 PF01148.15 KFY00759.1 - 1.4e-06 28.2 16.5 0.00013 21.7 0.6 2.8 4 0 0 4 4 4 2 Cytidylyltransferase family FAM220 PF15487.1 KFY00759.1 - 0.18 11.1 1.7 0.28 10.5 1.2 1.2 1 0 0 1 1 1 0 FAM220 family zf-Tim10_DDP PF02953.10 KFY00760.1 - 4.2e-21 73.9 1.9 5.8e-21 73.5 1.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger RhoGAP PF00620.22 KFY00761.1 - 7.9e-40 135.9 0.0 1.2e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain DUF290 PF01060.18 KFY00761.1 - 0.16 12.0 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Transthyretin-like family DUF605 PF04652.11 KFY00762.1 - 1.5 8.1 23.7 2.6 7.3 16.4 1.4 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 KFY00780.1 - 1.8e-38 132.1 0.0 2.3e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY00780.1 - 1e-13 51.0 0.0 1.4e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFY00780.1 - 2.1e-05 24.4 0.0 0.0019 17.9 0.0 2.4 1 1 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KFY00780.1 - 0.061 12.1 0.1 0.092 11.5 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Adaptin_N PF01602.15 KFY00781.1 - 1.1e-105 353.9 0.2 1.4e-105 353.5 0.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KFY00781.1 - 5.4e-59 198.3 0.8 1e-58 197.4 0.5 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KFY00781.1 - 3.9e-15 55.9 0.3 2.9e-05 24.2 0.1 5.6 3 1 3 6 6 6 3 HEAT repeats HEAT_PBS PF03130.11 KFY00781.1 - 0.002 18.4 0.2 3.7 8.2 0.0 4.1 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat MRP-S35 PF10246.4 KFY00781.1 - 0.02 14.8 0.0 0.1 12.5 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial ribosomal protein MRP-S35 HEAT PF02985.17 KFY00781.1 - 0.11 12.6 7.8 1.4 9.1 0.2 4.4 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.1 KFY00781.1 - 0.12 12.8 1.1 0.86 10.1 0.7 2.6 1 0 0 1 1 1 0 HEAT-like repeat CDP-OH_P_transf PF01066.16 KFY00782.1 - 7.6e-16 58.2 4.1 7.6e-16 58.2 2.8 2.5 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Cupin_2 PF07883.6 KFY00792.1 - 0.099 12.1 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Cupin domain Cellulase PF00150.13 KFY00800.1 - 1.8e-51 175.0 0.2 2.2e-51 174.7 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KFY00800.1 - 2.3e-12 46.3 15.3 2.3e-12 46.3 10.6 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain TOBE_3 PF12857.2 KFY00800.1 - 0.12 12.2 0.0 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 TOBE-like domain AA_permease PF00324.16 KFY00802.1 - 5.1e-134 447.1 37.8 6.2e-134 446.9 26.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KFY00802.1 - 7e-35 120.3 41.0 9.4e-35 119.9 28.4 1.1 1 0 0 1 1 1 1 Amino acid permease RGS PF00615.14 KFY00811.1 - 3.2e-33 114.3 0.0 7e-33 113.2 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 KFY00811.1 - 1.1e-20 73.0 0.1 2.7e-16 59.0 0.0 3.0 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Fungal_trans PF04082.13 KFY00829.1 - 2e-15 56.3 0.1 3.3e-15 55.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Phospholip_A2_3 PF09056.6 KFY00830.1 - 6.6e-38 129.3 5.5 9.7e-38 128.8 3.8 1.2 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 MMR_HSR1 PF01926.18 KFY00831.1 - 3.1e-07 30.3 0.1 7e-07 29.2 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFY00831.1 - 1.6e-06 28.0 6.0 0.0052 16.6 0.3 2.8 2 1 1 3 3 3 2 Dynamin family AIG1 PF04548.11 KFY00831.1 - 0.00027 20.1 0.1 0.00045 19.4 0.1 1.3 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.13 KFY00831.1 - 0.00086 18.6 0.0 0.0017 17.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KFY00831.1 - 0.0034 17.8 0.1 0.0099 16.3 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein IIGP PF05049.8 KFY00831.1 - 0.0066 15.3 0.1 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) DUF258 PF03193.11 KFY00831.1 - 0.0088 15.2 0.5 0.03 13.4 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KFY00831.1 - 0.046 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 KFY00831.1 - 0.086 11.8 0.3 0.35 9.8 0.2 1.9 1 1 0 1 1 1 0 Septin AAA_24 PF13479.1 KFY00831.1 - 0.14 11.7 1.8 0.25 10.9 1.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KFY00831.1 - 0.17 12.1 1.1 9.1 6.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KFY00831.1 - 1 9.6 4.4 0.42 10.9 0.1 2.4 3 0 0 3 3 3 0 ABC transporter AAA_23 PF13476.1 KFY00831.1 - 6.1 7.1 8.6 0.32 11.2 0.5 2.3 2 0 0 2 2 2 0 AAA domain CEP19 PF14933.1 KFY00831.1 - 8.1 6.7 6.6 3.8 7.7 1.5 2.5 2 1 0 2 2 2 0 CEP19-like protein Abhydrolase_3 PF07859.8 KFY00833.1 - 2.9e-25 89.0 0.0 3.7e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KFY00833.1 - 8.5e-08 31.2 0.0 1.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KFY00833.1 - 0.0032 17.2 0.1 0.0049 16.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFY00833.1 - 0.0039 16.4 0.0 0.0077 15.4 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Syndecan PF01034.15 KFY00839.1 - 0.0029 17.2 0.1 0.008 15.8 0.1 1.7 1 0 0 1 1 1 1 Syndecan domain Toxin_57 PF15535.1 KFY00839.1 - 0.082 12.9 10.1 0.036 14.1 4.3 2.4 1 1 1 2 2 2 0 Putative toxin 57 Podoplanin PF05808.6 KFY00839.1 - 0.34 10.4 5.6 0.03 13.8 0.6 1.6 2 0 0 2 2 2 0 Podoplanin BatA PF07584.6 KFY00839.1 - 1.9 8.7 5.5 15 5.8 0.0 2.5 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal Glyco_hydro_18 PF00704.23 KFY00840.1 - 1.4e-46 159.5 0.0 2.3e-46 158.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 KFY00840.1 - 0.0021 18.0 2.8 0.0021 18.0 2.0 2.7 2 0 0 2 2 2 1 Chitin recognition protein DUF3142 PF11340.3 KFY00840.1 - 0.0037 16.9 0.0 0.0076 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) LysM PF01476.15 KFY00840.1 - 0.088 12.7 0.1 14 5.6 0.0 2.8 3 0 0 3 3 3 0 LysM domain Zn_clus PF00172.13 KFY00843.1 - 1e-07 31.7 7.9 1.7e-07 31.0 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFY00843.1 - 0.00033 19.3 1.1 0.00077 18.1 0.0 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain DUF2306 PF10067.4 KFY00844.1 - 2.5e-10 40.4 9.8 2.5e-10 40.4 6.8 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) Glyco_transf_28 PF03033.15 KFY00846.1 - 6.2e-18 64.8 0.1 1.4e-14 54.0 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KFY00846.1 - 2.8e-07 29.4 0.0 5.1e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UIM PF02809.15 KFY00846.1 - 0.002 17.5 0.6 0.31 10.7 0.0 3.3 3 0 0 3 3 3 1 Ubiquitin interaction motif Glyco_tran_28_C PF04101.11 KFY00846.1 - 0.0032 17.1 0.1 0.39 10.3 0.0 3.4 3 0 0 3 3 3 1 Glycosyltransferase family 28 C-terminal domain Zn_clus PF00172.13 KFY00847.1 - 6.3e-07 29.2 10.2 6.3e-07 29.2 7.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFY00847.1 - 3.8e-06 25.7 0.3 9e-06 24.5 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain BTAD PF03704.12 KFY00847.1 - 0.08 13.2 1.1 3.9 7.7 0.1 2.4 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_12 PF13424.1 KFY00848.1 - 6.5e-36 122.1 9.5 7.5e-11 41.8 0.0 6.4 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.1 KFY00848.1 - 5.1e-19 67.5 1.6 0.018 14.9 0.0 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.1 KFY00848.1 - 1.9e-08 33.4 7.0 0.43 10.5 0.0 6.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFY00848.1 - 3.5e-05 24.0 3.3 0.083 13.5 0.1 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat AAA_22 PF13401.1 KFY00848.1 - 8.4e-05 22.7 0.0 0.00028 21.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain TPR_16 PF13432.1 KFY00848.1 - 9.7e-05 22.9 0.1 0.014 16.0 0.0 3.4 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFY00848.1 - 0.00014 22.0 0.3 0.75 10.1 0.0 3.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFY00848.1 - 0.00041 19.9 7.4 0.98 9.1 0.1 5.7 5 1 2 7 7 7 1 TPR repeat TPR_2 PF07719.12 KFY00848.1 - 0.0019 17.9 10.6 5 7.3 0.0 6.8 8 0 0 8 8 8 1 Tetratricopeptide repeat NB-ARC PF00931.17 KFY00848.1 - 0.0045 15.8 0.0 0.016 14.1 0.0 1.8 1 1 0 1 1 1 1 NB-ARC domain Apc3 PF12895.2 KFY00848.1 - 0.0056 16.7 0.4 0.48 10.5 0.0 3.6 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 KFY00848.1 - 0.009 16.3 0.1 1.3 9.6 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFY00848.1 - 0.011 15.3 2.7 14 5.4 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat KxDL PF10241.4 KFY00848.1 - 0.017 15.0 0.1 0.052 13.4 0.1 1.9 1 0 0 1 1 1 0 Uncharacterized conserved protein PPR PF01535.15 KFY00848.1 - 0.021 14.7 5.2 21 5.3 0.1 4.6 5 0 0 5 5 5 0 PPR repeat TPR_12 PF13424.1 KFY00849.1 - 5.2e-34 116.0 5.5 9e-14 51.1 0.1 4.4 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 KFY00849.1 - 3.5e-30 103.0 7.3 2.3e-06 27.3 0.0 6.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 KFY00849.1 - 3.1e-11 42.1 2.1 0.0036 17.0 0.0 4.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFY00849.1 - 9.9e-11 40.7 1.5 0.011 15.5 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFY00849.1 - 1.2e-08 34.2 0.6 0.005 16.4 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFY00849.1 - 3.9e-08 33.2 1.5 2.6 8.8 0.0 5.8 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFY00849.1 - 7.1e-07 28.7 2.3 0.083 12.5 0.1 4.4 3 1 1 4 4 4 3 TPR repeat TPR_16 PF13432.1 KFY00849.1 - 1.4e-05 25.6 1.2 1.2 9.8 0.0 4.6 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFY00849.1 - 0.00039 20.0 0.1 5.4 7.0 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFY00849.1 - 0.00044 20.2 0.4 1.5 9.1 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFY00849.1 - 0.0021 18.3 2.1 1.3 9.4 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFY00849.1 - 0.067 13.6 0.7 5.6 7.6 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFY00849.1 - 0.16 12.4 0.9 17 6.1 0.0 4.5 6 0 0 6 6 5 0 Tetratricopeptide repeat Carn_acyltransf PF00755.15 KFY00850.1 - 1.5e-163 545.1 0.0 3.5e-149 497.6 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase PHD PF00628.24 KFY00853.1 - 9.5e-09 34.8 6.3 2.3e-08 33.5 4.4 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KFY00853.1 - 0.0031 16.7 2.9 0.0064 15.7 2.0 1.5 1 0 0 1 1 1 1 PHD-finger TPR_11 PF13414.1 KFY00854.1 - 5.3e-12 45.2 4.6 0.0022 17.6 0.0 5.2 5 0 0 5 5 5 4 TPR repeat TPR_17 PF13431.1 KFY00854.1 - 1.1e-05 25.2 0.2 0.027 14.6 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFY00854.1 - 0.013 16.0 13.2 15 6.5 0.9 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFY00854.1 - 0.015 15.5 5.7 4.7 7.6 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFY00854.1 - 1.2 9.9 15.7 3.4 8.4 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFY00854.1 - 1.4 8.6 11.3 6.2 6.6 0.5 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Cellulase PF00150.13 KFY00855.1 - 3.8e-41 141.1 6.9 3.6e-40 137.9 3.0 2.1 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.9 KFY00855.1 - 3e-24 84.6 5.9 3e-21 75.0 2.8 4.0 4 0 0 4 4 4 2 Carbohydrate binding domain X2 Transferase PF02458.10 KFY00857.1 - 3.2e-26 91.7 0.0 9.2e-25 86.9 0.0 2.0 2 0 0 2 2 2 2 Transferase family RHH_1 PF01402.16 KFY00857.1 - 0.14 12.0 0.3 5.7 6.9 0.1 2.6 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Abhydrolase_3 PF07859.8 KFY00858.1 - 1.1e-38 132.8 0.0 1.4e-37 129.3 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KFY00858.1 - 0.0041 15.7 0.0 0.059 12.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Herpes_gE PF02480.11 KFY00859.1 - 0.0045 15.3 0.2 0.0065 14.7 0.2 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 KFY00859.1 - 0.083 12.5 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF2615 PF11027.3 KFY00859.1 - 0.36 10.7 2.0 0.53 10.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) ORC6 PF05460.8 KFY00859.1 - 5.3 6.0 7.6 7.3 5.5 5.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) ChAPs PF09295.5 KFY00860.1 - 8.3e-157 521.9 0.0 1e-156 521.6 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.1 KFY00860.1 - 4.4e-07 29.9 0.5 0.63 10.8 0.0 5.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFY00860.1 - 0.00013 21.5 0.1 0.95 9.1 0.0 3.2 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 KFY00860.1 - 0.00027 21.1 0.0 0.15 12.4 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFY00860.1 - 0.00056 19.6 0.6 4.5 7.4 0.7 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFY00860.1 - 0.0098 15.6 0.8 0.25 11.2 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFY00860.1 - 0.042 13.6 2.2 1.5 8.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFY00860.1 - 0.085 12.6 0.0 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Bac_rhamnosid PF05592.6 KFY00862.1 - 3.3e-22 78.3 0.0 2.1e-16 59.2 0.0 2.2 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 KFY00862.1 - 2.5e-07 29.7 1.4 4.2e-07 29.0 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Trehalase PF01204.13 KFY00862.1 - 0.00041 19.1 0.0 0.00059 18.6 0.0 1.1 1 0 0 1 1 1 1 Trehalase FAD_binding_3 PF01494.14 KFY00863.1 - 6e-12 45.2 0.1 1.6e-11 43.9 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFY00863.1 - 5.8e-06 25.4 3.3 9.6e-06 24.7 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFY00863.1 - 1.7e-05 25.1 0.3 6.6e-05 23.2 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFY00863.1 - 0.00017 21.5 0.0 0.00047 20.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFY00863.1 - 0.0015 18.4 0.1 0.0056 16.5 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KFY00863.1 - 0.0062 15.9 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 KFY00863.1 - 0.024 13.7 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Fungal_trans PF04082.13 KFY00864.1 - 7.4e-12 44.6 0.0 1.1e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY00864.1 - 2.4e-07 30.5 10.1 3.9e-07 29.8 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_76 PF03663.9 KFY00865.1 - 1.4e-37 129.9 18.6 1.8e-37 129.6 12.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KFY00865.1 - 0.00028 20.0 0.2 0.36 9.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 Lactonase PF10282.4 KFY00867.1 - 5.2e-84 282.2 0.0 6.4e-84 281.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller MIP PF00230.15 KFY00868.1 - 3.8e-25 88.6 11.7 7.8e-25 87.6 8.1 1.5 1 1 0 1 1 1 1 Major intrinsic protein Ephrin_lbd PF01404.14 KFY00868.1 - 0.018 14.8 0.0 0.027 14.2 0.0 1.1 1 0 0 1 1 1 0 Ephrin receptor ligand binding domain Glyco_hydro_35 PF01301.14 KFY00870.1 - 8.5e-94 314.4 0.1 1.1e-93 314.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 KFY00870.1 - 2.7e-11 43.1 0.2 9.6e-11 41.3 0.1 1.7 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.1 KFY00870.1 - 3.3e-07 30.5 0.0 0.0012 19.0 0.0 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain NAD_binding_10 PF13460.1 KFY00871.1 - 6.5e-07 29.5 0.1 8.7e-07 29.1 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 KFY00871.1 - 0.021 14.7 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 KFY00871.1 - 0.07 12.0 0.0 4.2 6.2 0.0 2.4 2 1 0 2 2 2 0 Male sterility protein TPR_10 PF13374.1 KFY00872.1 - 6e-29 99.1 0.7 1.8e-11 43.5 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFY00872.1 - 7.1e-22 77.1 7.5 3e-12 46.2 0.8 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFY00872.1 - 6.4e-08 31.8 6.7 0.036 13.6 0.2 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFY00872.1 - 8.4e-07 29.5 1.0 0.011 16.3 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFY00872.1 - 1.2e-06 27.9 6.5 0.062 13.2 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFY00872.1 - 3e-06 26.6 3.8 0.015 15.0 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFY00872.1 - 6e-06 26.4 3.5 0.22 11.8 1.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFY00872.1 - 4.5e-05 23.0 2.2 0.00088 18.8 1.5 2.1 1 1 0 1 1 1 1 TPR repeat Apc3 PF12895.2 KFY00872.1 - 6e-05 23.0 0.3 0.00011 22.2 0.2 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 KFY00872.1 - 7.2e-05 22.6 5.8 0.38 11.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.9 KFY00872.1 - 0.00086 19.5 0.0 10 6.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 KFY00872.1 - 0.002 17.8 5.0 0.49 10.2 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFY00872.1 - 0.028 14.1 5.0 0.81 9.6 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat PPR PF01535.15 KFY00872.1 - 0.081 12.9 0.1 2.5 8.2 0.0 2.8 3 1 0 3 3 3 0 PPR repeat TPR_20 PF14561.1 KFY00872.1 - 0.099 12.7 0.9 3 8.0 0.1 2.8 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFY00872.1 - 4.5 7.9 6.9 38 5.0 0.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat zf-CCHC_6 PF15288.1 KFY00874.1 - 0.0087 15.7 2.3 0.021 14.4 1.6 1.7 1 0 0 1 1 1 1 Zinc knuckle Fil_haemagg_2 PF13332.1 KFY00874.1 - 0.0096 15.7 0.8 0.013 15.3 0.6 1.1 1 0 0 1 1 1 1 Haemagluttinin repeat zf-CCHC_4 PF14392.1 KFY00874.1 - 0.011 15.3 0.7 0.023 14.3 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle FRG2 PF15315.1 KFY00874.1 - 0.065 13.2 5.5 0.087 12.7 3.8 1.2 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Selenoprotein_S PF06936.6 KFY00874.1 - 0.1 12.1 3.9 0.11 12.0 2.7 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) DCA16 PF15349.1 KFY00875.1 - 0.12 11.7 3.6 0.17 11.1 2.5 1.2 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 Ank_2 PF12796.2 KFY00876.1 - 0.004 17.4 0.0 0.074 13.3 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Hexokinase_2 PF03727.11 KFY00877.1 - 3.5e-30 104.9 0.1 3.9e-30 104.8 0.1 1.0 1 0 0 1 1 1 1 Hexokinase MiAMP1 PF09117.5 KFY00877.1 - 0.028 14.8 0.2 0.044 14.1 0.1 1.2 1 0 0 1 1 1 0 MiAMP1 Glyco_transf_8 PF01501.15 KFY00878.1 - 3.4e-33 115.0 0.1 5.5e-33 114.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KFY00878.1 - 0.02 14.2 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Cation_efflux PF01545.16 KFY00879.1 - 1.3e-29 103.1 5.2 1.8e-29 102.6 3.6 1.2 1 0 0 1 1 1 1 Cation efflux family zf-rbx1 PF12678.2 KFY00879.1 - 2.8e-11 43.3 0.2 6.7e-11 42.1 0.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KFY00879.1 - 2.7e-10 39.9 5.5 7.1e-10 38.5 1.4 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KFY00879.1 - 4.2e-07 29.5 3.8 6.4e-06 25.7 0.8 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFY00879.1 - 6.5e-06 25.7 0.3 2e-05 24.1 0.2 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFY00879.1 - 4.4e-05 23.1 2.7 0.00036 20.2 2.1 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFY00879.1 - 6.9e-05 22.7 1.8 6.9e-05 22.7 1.3 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KFY00879.1 - 0.016 15.0 1.4 0.081 12.7 0.3 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KFY00879.1 - 0.042 13.5 5.4 0.18 11.5 3.7 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFY00879.1 - 0.078 12.8 1.2 0.22 11.4 0.8 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KFY00879.1 - 0.12 11.9 0.8 0.32 10.6 0.6 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF3455 PF11937.3 KFY00881.1 - 7.6e-45 153.0 0.1 9.2e-45 152.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF3317 PF11779.3 KFY00889.1 - 0.00043 19.6 2.0 0.0006 19.1 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) CENP-I PF07778.6 KFY00890.1 - 2.7e-83 279.9 0.0 4.2e-56 190.2 0.0 2.1 2 0 0 2 2 2 2 Mis6 TIR PF01582.15 KFY00892.1 - 0.059 12.8 0.0 0.078 12.4 0.0 1.2 1 0 0 1 1 1 0 TIR domain Saccharop_dh PF03435.13 KFY00893.1 - 3.7e-131 437.6 0.0 4.1e-131 437.5 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KFY00893.1 - 3.5e-08 33.6 0.2 5.4e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KFY00893.1 - 0.00013 22.0 1.5 0.00021 21.3 1.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding IlvN PF07991.7 KFY00893.1 - 0.00039 19.8 2.5 0.0012 18.1 0.7 2.5 2 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain GFO_IDH_MocA PF01408.17 KFY00893.1 - 0.0032 17.9 0.5 0.0063 17.0 0.4 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 KFY00893.1 - 0.0084 16.4 1.1 0.015 15.6 0.8 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KFY00893.1 - 0.023 14.9 0.3 0.045 14.0 0.2 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NmrA PF05368.8 KFY00893.1 - 0.095 11.9 0.6 0.17 11.0 0.4 1.4 1 0 0 1 1 1 0 NmrA-like family USP7_C2 PF14533.1 KFY00893.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal TRAPPC9-Trs120 PF08626.6 KFY00895.1 - 1.3e-150 503.0 0.0 9e-150 500.2 0.0 2.3 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit CARDB PF07705.6 KFY00895.1 - 0.28 11.2 0.0 3 7.9 0.0 2.5 2 0 0 2 2 2 0 CARDB DUF2404 PF10296.4 KFY00896.1 - 6e-08 32.7 0.0 1.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) RtcB PF01139.12 KFY00896.1 - 0.1 11.5 0.2 0.31 10.0 0.0 1.7 2 0 0 2 2 2 0 tRNA-splicing ligase RtcB CDP-OH_P_transf PF01066.16 KFY00897.1 - 9.1e-17 61.2 6.2 1.7e-16 60.3 4.3 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Tyr-DNA_phospho PF06087.7 KFY00898.1 - 5.8e-75 252.5 0.0 7.8e-75 252.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 KFY00898.1 - 0.00083 19.1 0.0 0.017 14.8 0.0 2.5 2 0 0 2 2 2 1 PLD-like domain UIM PF02809.15 KFY00898.1 - 0.0085 15.5 1.9 0.0085 15.5 1.3 2.6 2 0 0 2 2 2 1 Ubiquitin interaction motif IPPT PF01715.12 KFY00899.1 - 1.2e-53 181.6 0.3 5.7e-53 179.5 0.2 2.0 1 1 0 1 1 1 1 IPP transferase IPT PF01745.11 KFY00899.1 - 0.00011 21.4 0.1 0.00026 20.2 0.0 1.6 2 0 0 2 2 2 1 Isopentenyl transferase zf-met PF12874.2 KFY00899.1 - 0.00016 21.7 0.2 0.00032 20.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_33 PF13671.1 KFY00899.1 - 0.0015 18.4 0.1 0.073 12.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFY00899.1 - 0.0023 18.7 0.1 0.0053 17.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFY00899.1 - 0.01 15.2 0.0 0.025 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KFY00899.1 - 0.01 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 KFY00899.1 - 0.015 15.5 0.0 0.042 14.1 0.0 1.7 1 1 0 1 1 1 0 ABC transporter zf-C2H2_jaz PF12171.3 KFY00899.1 - 0.018 15.1 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding PhoH PF02562.11 KFY00899.1 - 0.036 13.3 0.0 0.086 12.0 0.0 1.5 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.1 KFY00899.1 - 0.037 14.3 0.1 1.6 9.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KFY00899.1 - 0.083 13.0 0.0 0.27 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Pex2_Pex12 PF04757.9 KFY00899.1 - 0.1 12.0 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region SecY PF00344.15 KFY00900.1 - 2.3e-96 322.7 12.3 2.9e-96 322.4 8.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 KFY00900.1 - 1e-18 66.5 0.3 7.8e-18 63.6 0.2 2.5 2 0 0 2 2 2 1 Plug domain of Sec61p ABC_tran PF00005.22 KFY00901.1 - 9.3e-51 171.7 0.0 8.2e-29 100.6 0.0 2.8 2 1 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KFY00901.1 - 1.2e-45 156.0 25.6 7.4e-26 91.1 5.2 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 KFY00901.1 - 3.4e-09 37.0 2.0 0.1 12.5 0.0 4.6 5 0 0 5 5 4 2 AAA domain SMC_N PF02463.14 KFY00901.1 - 1.1e-08 34.6 0.3 0.0016 17.6 0.0 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KFY00901.1 - 4e-06 27.2 3.6 0.00053 20.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 KFY00901.1 - 4.3e-05 23.0 0.0 0.038 13.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KFY00901.1 - 5.2e-05 22.4 0.0 0.029 13.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFY00901.1 - 6.3e-05 22.4 0.2 0.24 10.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KFY00901.1 - 7.6e-05 22.6 0.3 0.19 11.6 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 KFY00901.1 - 0.0001 23.1 0.2 0.36 11.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KFY00901.1 - 0.00029 20.9 0.0 4.8 7.3 0.0 3.6 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 KFY00901.1 - 0.00033 19.8 2.0 0.077 12.0 0.1 2.9 3 0 0 3 3 3 1 Zeta toxin DUF87 PF01935.12 KFY00901.1 - 0.00036 20.4 1.3 0.029 14.1 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 KFY00901.1 - 0.00044 20.7 0.2 1.3 9.5 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 KFY00901.1 - 0.00082 19.4 0.3 1.5 8.7 0.0 3.2 2 1 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 KFY00901.1 - 0.00084 18.3 0.1 0.025 13.4 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.1 KFY00901.1 - 0.001 19.3 0.9 0.6 10.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 KFY00901.1 - 0.0021 17.5 0.1 1.6 8.0 0.0 3.1 3 0 0 3 3 3 1 AAA-like domain MobB PF03205.9 KFY00901.1 - 0.0048 16.6 0.2 1.9 8.1 0.0 3.3 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KFY00901.1 - 0.01 15.2 0.1 3.4 7.0 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 KFY00901.1 - 0.016 15.4 0.0 1.8 8.8 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KFY00901.1 - 0.017 14.5 0.1 6.3 6.1 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein HemX PF04375.9 KFY00901.1 - 0.018 13.6 0.4 0.03 12.9 0.3 1.3 1 0 0 1 1 1 0 HemX AAA_33 PF13671.1 KFY00901.1 - 0.072 12.9 0.0 4 7.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain Wzy_C PF04932.10 KFY00901.1 - 0.11 12.2 10.6 0.023 14.5 1.2 3.5 3 1 1 4 4 4 0 O-Antigen ligase ResIII PF04851.10 KFY00901.1 - 0.15 11.8 0.1 8.3 6.1 0.0 2.9 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit cobW PF02492.14 KFY00901.1 - 0.63 9.4 2.5 2 7.8 0.2 2.6 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Mur_ligase_C PF02875.16 KFY00908.1 - 0.034 14.1 0.0 0.09 12.8 0.0 1.7 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Spc7_N PF15402.1 KFY00909.1 - 1.5e-247 824.1 74.9 5.2e-247 822.3 51.9 2.9 1 1 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 KFY00909.1 - 6e-107 357.0 5.5 1.1e-106 356.2 3.8 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 KFY00909.1 - 2.7e-09 36.5 0.1 5.2e-09 35.6 0.1 1.5 1 0 0 1 1 1 1 Spc7_C2 IncA PF04156.9 KFY00909.1 - 3.3 7.2 9.0 11 5.5 6.2 1.9 1 0 0 1 1 1 0 IncA protein Ribosomal_S17 PF00366.15 KFY00910.1 - 1.2e-29 102.1 0.5 1.7e-29 101.6 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S17 SecE PF00584.15 KFY00917.1 - 1e-12 47.4 0.0 1.2e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex WD40 PF00400.27 KFY00918.1 - 5.3e-23 80.0 12.2 1.1e-08 34.6 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Daxx PF03344.10 KFY00918.1 - 5.9 5.2 10.0 8.9 4.6 7.0 1.2 1 0 0 1 1 1 0 Daxx Family Myb_DNA-binding PF00249.26 KFY00919.1 - 7e-18 64.4 0.7 2.2e-09 37.2 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFY00919.1 - 3.5e-14 52.6 0.1 1.1e-05 25.4 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Semialdhyde_dhC PF02774.13 KFY00920.1 - 2.6e-39 135.0 0.0 3.4e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 KFY00920.1 - 3.2e-29 101.6 0.0 2e-28 99.1 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KFY00920.1 - 0.00062 19.6 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 KFY00920.1 - 0.018 15.6 0.0 0.048 14.1 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Saccharop_dh PF03435.13 KFY00920.1 - 0.03 13.3 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Gp_dh_C PF02800.15 KFY00920.1 - 0.078 12.4 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain SAICAR_synt PF01259.13 KFY00921.1 - 5e-86 287.8 0.0 5.9e-86 287.6 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Ribosomal_S4e PF00900.15 KFY00922.1 - 5.6e-32 109.2 0.2 1.1e-31 108.2 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 KFY00922.1 - 1.2e-18 66.6 4.9 2.3e-18 65.7 3.4 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 KFY00922.1 - 6e-07 28.8 0.0 1.2e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 KFY00922.1 - 0.0018 17.8 3.9 0.0028 17.3 0.4 3.0 3 0 0 3 3 3 1 KOW motif FAD-oxidase_C PF02913.14 KFY00923.1 - 1.5e-60 204.5 0.1 2.1e-60 204.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KFY00923.1 - 2.9e-33 114.2 0.0 5.6e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 KFY00923.1 - 0.064 11.7 0.0 0.13 10.7 0.0 1.4 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) RdRP PF05183.7 KFY00924.1 - 1.3e-184 615.1 0.1 1.8e-184 614.6 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF3942 PF13078.1 KFY00924.1 - 0.036 14.1 0.0 0.096 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3942) RRM_1 PF00076.17 KFY00924.1 - 0.076 12.6 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF605 PF04652.11 KFY00927.1 - 0.7 9.2 15.9 0.94 8.8 11.0 1.2 1 0 0 1 1 1 0 Vta1 like Peptidase_S8 PF00082.17 KFY00929.1 - 1.1e-50 172.4 14.0 1.5e-50 171.9 9.7 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KFY00929.1 - 2.2e-08 34.5 0.8 4.4e-08 33.5 0.5 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 CBM_2 PF00553.14 KFY00929.1 - 0.0091 16.0 0.1 0.026 14.5 0.1 1.8 1 0 0 1 1 1 1 Cellulose binding domain DNA_pol_viral_N PF00242.12 KFY00929.1 - 0.2 10.6 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Arginase PF00491.16 KFY00930.1 - 2.2e-32 112.4 0.0 2.7e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family BTB PF00651.26 KFY00931.1 - 2.5e-14 53.2 0.0 3.7e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DNA_RNApol_7kD PF03604.8 KFY00931.1 - 0.49 9.9 4.1 11 5.5 0.2 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Prok-RING_1 PF14446.1 KFY00931.1 - 1.2 8.9 7.0 0.82 9.4 1.9 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 MOSC_N PF03476.11 KFY00934.1 - 6e-13 48.5 0.0 1.3e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 KFY00934.1 - 9.6e-11 41.2 0.0 1.5e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 MOSC domain Mito_carr PF00153.22 KFY00936.1 - 4.7e-54 180.0 2.0 1.4e-18 66.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein vWA-TerF-like PF10138.4 KFY00951.1 - 5e-07 29.7 0.0 8.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 KFY00951.1 - 0.1 12.6 0.3 0.47 10.5 0.0 2.2 2 1 0 2 2 2 0 von Willebrand factor type A domain ABC2_membrane PF01061.19 KFY00952.1 - 9.8e-86 286.2 48.6 1.8e-48 164.4 14.5 3.2 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 KFY00952.1 - 2.1e-40 138.1 0.0 4.9e-19 68.9 0.0 2.9 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 KFY00952.1 - 7e-24 83.4 6.7 2e-23 81.9 0.0 2.9 3 0 0 3 3 2 1 CDR ABC transporter Fungal_trans PF04082.13 KFY00952.1 - 2.5e-14 52.7 0.1 4.8e-14 51.8 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane_3 PF12698.2 KFY00952.1 - 2.6e-11 43.1 33.2 1.1e-07 31.2 10.2 2.9 3 0 0 3 3 3 2 ABC-2 family transporter protein Zn_clus PF00172.13 KFY00952.1 - 6.5e-09 35.5 10.5 1.3e-08 34.6 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA_22 PF13401.1 KFY00952.1 - 1.3e-06 28.5 0.4 0.15 12.2 0.0 4.2 4 1 0 4 4 3 2 AAA domain AAA_25 PF13481.1 KFY00952.1 - 1.4e-05 24.5 0.1 0.017 14.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFY00952.1 - 0.00042 20.3 0.3 0.24 11.3 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KFY00952.1 - 0.00062 20.5 0.0 1.9 9.2 0.0 3.1 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 KFY00952.1 - 0.00076 18.9 0.5 0.5 9.7 0.2 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KFY00952.1 - 0.0012 18.1 0.0 0.0083 15.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_trans_N PF14510.1 KFY00952.1 - 0.0013 18.8 0.1 0.0032 17.5 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_28 PF13521.1 KFY00952.1 - 0.0014 18.6 0.2 0.46 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KFY00952.1 - 0.0016 18.3 0.0 2.1 8.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KFY00952.1 - 0.0038 16.7 0.6 0.13 11.8 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KFY00952.1 - 0.0056 16.9 1.0 2.5 8.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 KFY00952.1 - 0.0076 15.9 0.5 3.9 7.0 0.1 2.5 2 0 0 2 2 2 2 NACHT domain AAA_19 PF13245.1 KFY00952.1 - 0.0096 15.6 0.4 2.3 8.0 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain Arch_ATPase PF01637.13 KFY00952.1 - 0.012 15.2 0.0 3.1 7.4 0.0 2.8 2 0 0 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 KFY00952.1 - 0.024 14.1 0.8 2.5 7.5 0.2 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 KFY00952.1 - 0.039 13.9 0.3 2.2 8.1 0.0 3.2 4 0 0 4 4 3 0 AAA domain AAA PF00004.24 KFY00952.1 - 0.065 13.4 0.0 10 6.3 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KFY00952.1 - 0.18 10.6 0.0 4.3 6.1 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein UPF0079 PF02367.12 KFY00952.1 - 0.26 10.9 0.7 8.9 5.9 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 TPR_11 PF13414.1 KFY00954.1 - 1.4e-11 43.8 5.0 0.00012 21.6 0.1 4.0 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 KFY00954.1 - 1.1e-09 37.4 10.1 0.0092 15.8 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFY00954.1 - 8.1e-07 28.8 5.2 0.021 14.7 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFY00954.1 - 1.4e-05 24.5 4.3 0.29 10.8 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFY00954.1 - 0.0014 18.8 8.3 0.27 11.6 0.3 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.9 KFY00954.1 - 0.0052 17.0 5.2 0.51 10.9 1.5 3.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFY00954.1 - 0.016 15.8 12.1 1.7 9.4 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFY00954.1 - 0.036 13.8 0.9 4.3 7.3 0.1 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFY00954.1 - 0.039 14.6 18.6 2.1 9.1 0.3 5.9 5 1 1 6 6 6 0 Tetratricopeptide repeat PSII PF00421.14 KFY00954.1 - 0.064 11.8 0.0 0.1 11.1 0.0 1.3 1 0 0 1 1 1 0 Photosystem II protein Epimerase PF01370.16 KFY00955.1 - 3.1e-13 49.7 0.2 3e-12 46.4 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFY00955.1 - 8.8e-05 22.5 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KFY00955.1 - 0.0001 21.4 0.1 0.00015 20.9 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 KFY00955.1 - 0.00012 21.4 0.1 0.0002 20.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KFY00955.1 - 0.012 14.5 0.8 0.71 8.7 0.0 2.5 1 1 0 2 2 2 0 Male sterility protein RmlD_sub_bind PF04321.12 KFY00955.1 - 0.017 13.9 0.1 0.88 8.4 0.0 2.7 2 1 1 3 3 3 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 KFY00955.1 - 0.049 12.3 0.0 0.08 11.6 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KFY00955.1 - 0.094 13.0 0.1 0.47 10.7 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain ABM PF03992.11 KFY00956.1 - 3.4e-05 23.7 0.1 3.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Fungal_trans_2 PF11951.3 KFY00957.1 - 3.2e-16 58.9 0.1 4e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ion_trans PF00520.26 KFY00957.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Ion transport protein Fungal_trans_2 PF11951.3 KFY00958.1 - 8.5e-11 41.0 1.9 1.2e-10 40.6 1.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY00958.1 - 2.7e-05 23.9 8.1 4.2e-05 23.3 5.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-ribbon_3 PF13248.1 KFY00958.1 - 1.5 8.1 7.1 0.41 9.9 2.5 1.9 2 0 0 2 2 2 0 zinc-ribbon domain Gly_transf_sug PF04488.10 KFY00960.1 - 1.5e-08 34.9 0.0 3.6e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KFY00960.1 - 0.012 14.1 0.1 0.019 13.4 0.1 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Stn1 PF10451.4 KFY00961.1 - 0.0015 17.4 0.0 0.0017 17.2 0.0 1.1 1 0 0 1 1 1 1 Telomere regulation protein Stn1 Ribosomal_S7 PF00177.16 KFY00962.1 - 2.5e-26 92.0 0.0 4.3e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e dsrm PF00035.20 KFY00963.1 - 0.0009 19.7 0.0 0.0017 18.8 0.0 1.4 1 1 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KFY00963.1 - 0.0037 17.5 0.1 0.016 15.5 0.1 1.9 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 RPA_interact_N PF14766.1 KFY00963.1 - 0.024 14.0 0.1 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Replication protein A interacting N-terminal DUF2183 PF09949.4 KFY00966.1 - 4.7e-32 109.8 0.0 2.1e-31 107.7 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) AMP-binding PF00501.23 KFY00966.1 - 9.6e-10 37.4 0.1 0.00037 19.0 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme CarboxypepD_reg PF13620.1 KFY00966.1 - 0.074 13.1 0.2 0.4 10.7 0.1 2.2 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain DEAD PF00270.24 KFY00967.1 - 1.2e-43 148.5 0.0 2.7e-43 147.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFY00967.1 - 8.2e-25 86.4 0.0 1.8e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KFY00967.1 - 0.0081 14.6 0.0 0.0081 14.6 0.0 2.9 2 1 2 4 4 4 1 Protein of unknown function (DUF1253) Acetyltransf_10 PF13673.1 KFY00968.1 - 0.0029 17.7 0.0 0.0082 16.2 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFY00968.1 - 0.018 15.0 0.0 0.032 14.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KFY00968.1 - 0.12 12.5 0.0 0.36 10.9 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Arf PF00025.16 KFY00969.1 - 3.1e-68 228.4 0.4 3.4e-68 228.2 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFY00969.1 - 6.6e-14 51.6 0.0 7.6e-14 51.4 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KFY00969.1 - 1.3e-12 47.1 1.1 3.5e-07 29.2 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KFY00969.1 - 4.1e-10 40.1 0.0 5.7e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KFY00969.1 - 5.5e-10 38.7 0.0 6.3e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFY00969.1 - 1.3e-08 34.8 0.0 1.6e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFY00969.1 - 3.1e-07 29.7 0.0 3.8e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KFY00969.1 - 5.2e-06 26.0 0.0 0.00054 19.4 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 KFY00969.1 - 0.033 13.4 0.2 0.096 11.9 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 KFY00969.1 - 0.039 13.4 0.1 0.097 12.1 0.0 1.7 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 KFY00969.1 - 0.046 14.5 0.1 0.059 14.1 0.1 1.3 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 KFY00969.1 - 0.055 13.1 0.1 0.8 9.3 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.18 KFY00969.1 - 0.077 12.8 0.0 0.56 9.9 0.0 2.0 2 0 0 2 2 2 0 Dynamin family 6PF2K PF01591.13 KFY00969.1 - 0.13 11.2 0.0 0.26 10.3 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DUF4045 PF13254.1 KFY00970.1 - 6.4e-95 318.8 45.1 3.3e-59 201.2 19.7 4.7 3 2 2 5 5 5 2 Domain of unknown function (DUF4045) PDEase_II PF02112.10 KFY00971.1 - 4.9e-55 186.7 0.0 2.8e-46 157.9 0.0 3.0 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 KFY00971.1 - 0.00091 18.8 0.2 0.0036 16.8 0.0 2.1 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KFY00971.1 - 0.011 15.3 3.5 0.064 12.9 1.6 2.6 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily PSI_PSAK PF01241.13 KFY00971.1 - 0.046 13.7 0.0 0.099 12.6 0.0 1.5 1 0 0 1 1 1 0 Photosystem I psaG / psaK Chlorosome_CsmC PF11098.3 KFY00975.1 - 8.5 6.0 16.1 25 4.5 11.1 1.9 1 1 0 1 1 1 0 Chlorosome envelope protein C DUF3614 PF12267.3 KFY00976.1 - 6.2 7.0 7.0 0.82 9.9 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) DUF605 PF04652.11 KFY00977.1 - 3.3 7.0 12.4 3.6 6.8 8.6 1.0 1 0 0 1 1 1 0 Vta1 like eIF-3_zeta PF05091.7 KFY00977.1 - 3.4 6.1 6.2 3.8 6.0 4.3 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Lin-8 PF03353.10 KFY00977.1 - 3.7 6.7 10.2 4 6.6 7.1 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Tsg PF04668.7 KFY00980.1 - 0.055 13.6 0.3 0.068 13.3 0.2 1.1 1 0 0 1 1 1 0 Twisted gastrulation (Tsg) protein conserved region DUF3659 PF12396.3 KFY00982.1 - 2.3e-118 385.9 61.5 8.4e-24 83.0 5.3 6.5 6 0 0 6 6 6 6 Protein of unknown function (DUF3659) GCK PF07802.6 KFY00982.1 - 0.029 14.4 0.4 0.063 13.4 0.2 1.5 1 0 0 1 1 1 0 GCK domain DUF842 PF05811.8 KFY00982.1 - 0.085 12.3 0.6 0.22 10.9 0.4 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) SchA_CurD PF04486.7 KFY00982.1 - 0.091 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 SchA/CurD like domain CorA PF01544.13 KFY00982.1 - 0.41 9.6 0.2 0.78 8.7 0.1 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein 2H-phosphodiest PF08975.5 KFY00983.1 - 6.1e-13 48.5 0.0 1.1e-11 44.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1868) LigT_PEase PF02834.11 KFY00983.1 - 7.1e-05 22.7 0.0 0.00017 21.4 0.0 1.7 1 0 0 1 1 1 1 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.1 KFY00983.1 - 0.00016 21.3 0.1 0.00059 19.5 0.0 1.9 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily HVSL PF09749.4 KFY00983.1 - 0.083 11.9 0.0 0.2 10.6 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein DUF3430 PF11912.3 KFY00984.1 - 0.062 13.1 0.0 0.08 12.7 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3430) Catalase PF00199.14 KFY00985.1 - 1.6e-183 609.6 4.0 2e-183 609.4 2.8 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KFY00985.1 - 8.5e-12 44.7 0.5 2.6e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 Catalase-related immune-responsive ECH PF00378.15 KFY00986.1 - 9e-28 97.0 0.1 1e-27 96.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 KFY00986.1 - 0.094 12.8 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Transferase PF02458.10 KFY00987.1 - 2.6e-28 98.6 0.0 1.5e-27 96.0 0.0 1.8 1 1 0 1 1 1 1 Transferase family Condensation PF00668.15 KFY00987.1 - 0.031 13.1 0.0 0.06 12.1 0.0 1.4 1 0 0 1 1 1 0 Condensation domain CHZ PF09649.5 KFY00987.1 - 0.1 11.8 0.1 0.31 10.2 0.1 1.7 1 0 0 1 1 1 0 Histone chaperone domain CHZ Kinesin PF00225.18 KFY00990.1 - 2.5e-33 115.2 0.0 4.1e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain ADIP PF11559.3 KFY00990.1 - 0.044 13.6 2.7 0.12 12.2 0.9 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding HALZ PF02183.13 KFY00990.1 - 0.08 12.6 0.9 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Herpes_BLRF2 PF05812.7 KFY00990.1 - 0.64 9.8 4.8 3.6 7.4 1.7 2.4 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein DivIVA PF05103.8 KFY00990.1 - 2.3 8.2 7.0 3.6 7.6 2.7 2.2 2 0 0 2 2 2 0 DivIVA protein bZIP_2 PF07716.10 KFY00990.1 - 7.7 6.4 9.9 2.8 7.8 1.6 2.8 2 0 0 2 2 2 0 Basic region leucine zipper PGAP1 PF07819.8 KFY00991.1 - 0.11 12.0 0.1 1.4 8.4 0.0 2.2 1 1 0 1 1 1 0 PGAP1-like protein TT_ORF2a PF08197.6 KFY00993.1 - 0.32 10.7 2.0 0.61 9.8 0.2 2.1 2 0 0 2 2 2 0 pORF2a truncated protein Fungal_trans PF04082.13 KFY00994.1 - 2.2e-12 46.3 0.4 3.2e-12 45.8 0.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_31 PF01055.21 KFY00995.1 - 4.3e-84 282.8 3.0 5.8e-84 282.4 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Sugar_tr PF00083.19 KFY00996.1 - 1.6e-82 277.4 25.0 1.9e-82 277.2 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY00996.1 - 2.1e-15 56.3 29.6 2.1e-15 56.3 20.5 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFY00996.1 - 0.00076 17.9 5.6 0.00076 17.9 3.9 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein Fungal_trans PF04082.13 KFY00997.1 - 2.3e-15 56.1 1.8 4.4e-15 55.2 1.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY00997.1 - 2.7e-08 33.5 12.5 4.5e-08 32.8 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hemerythrin PF01814.18 KFY00997.1 - 0.038 14.1 0.2 5.4 7.1 0.0 2.7 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain NmrA PF05368.8 KFY00998.1 - 3.6e-36 124.5 0.0 4.7e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFY00998.1 - 1.6e-14 54.3 0.0 2e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFY00998.1 - 0.00041 19.1 0.0 0.00079 18.2 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KFY00998.1 - 0.0019 17.8 0.0 0.0049 16.5 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KFY00998.1 - 0.0029 17.0 0.0 0.038 13.4 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFY00998.1 - 0.0034 16.3 0.0 0.012 14.5 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 KFY00998.1 - 0.007 16.3 0.0 0.015 15.1 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase DapB_N PF01113.15 KFY00998.1 - 0.11 12.3 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 KFY00998.1 - 0.11 12.9 0.1 0.2 12.2 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase CDH PF02611.10 KFY00999.1 - 0.0065 15.7 0.1 0.01 15.1 0.1 1.2 1 0 0 1 1 1 1 CDP-diacylglycerol pyrophosphatase Meth_synt_2 PF01717.13 KFY00999.1 - 0.16 10.9 0.0 0.29 10.0 0.0 1.4 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain NACHT PF05729.7 KFY01000.1 - 1.1e-09 38.2 0.0 2.1e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.2 KFY01000.1 - 0.00011 22.1 0.7 0.00065 19.6 0.2 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 KFY01000.1 - 0.00026 20.3 0.0 0.00046 19.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KFY01000.1 - 0.00065 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KFY01000.1 - 0.0043 16.8 0.0 0.017 14.8 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Epimerase PF01370.16 KFY01001.1 - 5.5e-19 68.5 0.0 7.7e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFY01001.1 - 5.6e-10 39.5 0.0 1.1e-09 38.5 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KFY01001.1 - 5.8e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KFY01001.1 - 0.00023 20.1 0.0 0.00089 18.2 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KFY01001.1 - 0.014 14.0 0.0 0.03 13.0 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family 2-oxoacid_dh PF00198.18 KFY01001.1 - 0.026 13.7 0.0 0.041 13.1 0.0 1.2 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) NmrA PF05368.8 KFY01001.1 - 0.033 13.4 0.1 5.8 6.1 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family Fungal_trans PF04082.13 KFY01002.1 - 6.3e-06 25.2 0.0 6.3e-06 25.2 0.0 2.8 3 1 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY01002.1 - 9.7e-06 25.4 10.5 9.7e-06 25.4 7.3 1.9 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_5 PF12695.2 KFY01003.1 - 1.4e-16 60.5 0.1 2.2e-16 59.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KFY01003.1 - 1.1e-07 31.3 1.5 2e-07 30.5 0.4 1.9 2 1 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.3 KFY01003.1 - 0.0048 16.7 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase BAAT_C PF08840.6 KFY01003.1 - 0.0083 15.8 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2410 PF10307.4 KFY01005.1 - 4.7e-79 264.3 0.0 6.2e-79 263.9 0.0 1.1 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) DNA_primase_S PF01896.14 KFY01006.1 - 3e-55 186.0 0.1 4.7e-55 185.3 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit BTB PF00651.26 KFY01007.1 - 1e-09 38.3 0.0 1.8e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.2 KFY01012.1 - 1.5e-07 31.0 0.0 5.2e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFY01012.1 - 0.0001 21.8 0.0 0.00036 20.1 0.0 2.0 1 0 0 1 1 1 1 F-box domain SNARE PF05739.14 KFY01013.1 - 1.9e-11 43.4 3.3 1.9e-11 43.4 2.3 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KFY01013.1 - 2.4e-07 30.8 0.8 2.4e-07 30.8 0.5 2.6 3 0 0 3 3 2 1 Syntaxin DUF4094 PF13334.1 KFY01013.1 - 0.0019 18.5 1.5 0.0092 16.3 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4094) PTA_PTB PF01515.14 KFY01013.1 - 0.0038 16.3 2.5 0.0054 15.8 1.7 1.2 1 0 0 1 1 1 1 Phosphate acetyl/butaryl transferase T2SF PF00482.18 KFY01013.1 - 0.018 14.9 2.4 0.061 13.2 1.5 2.0 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F V-SNARE PF05008.10 KFY01013.1 - 0.02 15.0 7.2 0.026 14.6 1.2 3.0 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Rifin_STEVOR PF02009.11 KFY01013.1 - 0.024 14.3 5.5 0.03 13.9 3.2 1.4 1 1 0 1 1 1 0 Rifin/stevor family MCPsignal PF00015.16 KFY01013.1 - 0.029 13.8 8.5 0.019 14.5 4.1 1.8 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Vac_Fusion PF02346.11 KFY01013.1 - 0.039 13.3 6.1 0.11 11.8 0.1 2.9 3 0 0 3 3 3 0 Chordopoxvirus fusion protein Claudin_3 PF06653.6 KFY01013.1 - 0.041 13.5 0.6 0.066 12.9 0.4 1.2 1 0 0 1 1 1 0 Tight junction protein, Claudin-like Bap31 PF05529.7 KFY01013.1 - 0.054 12.9 0.1 0.054 12.9 0.1 2.4 1 1 2 3 3 3 0 B-cell receptor-associated protein 31-like Allexi_40kDa PF05549.6 KFY01013.1 - 0.055 12.7 5.0 0.13 11.5 0.1 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF3357 PF11837.3 KFY01013.1 - 0.066 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) UPF0118 PF01594.11 KFY01013.1 - 0.072 12.0 2.6 0.19 10.6 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function DUF20 HHH_2 PF12826.2 KFY01013.1 - 0.13 12.1 0.4 0.13 12.1 0.3 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif Poty_PP PF08440.5 KFY01013.1 - 0.83 8.6 5.7 0.28 10.2 0.7 2.0 2 0 0 2 2 2 0 Potyviridae polyprotein SP_C-Propep PF08999.5 KFY01013.1 - 2.6 7.5 6.4 5 6.6 4.4 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Spectrin PF00435.16 KFY01013.1 - 3.3 8.0 8.7 5.4 7.3 1.5 2.7 2 1 0 2 2 2 0 Spectrin repeat Methyltransf_23 PF13489.1 KFY01024.1 - 1.6e-13 50.6 0.0 2.4e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY01024.1 - 5.5e-08 32.5 0.0 3.4e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY01024.1 - 6.3e-08 33.1 0.0 8.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY01024.1 - 4.4e-07 30.3 0.0 1.9e-06 28.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY01024.1 - 4.8e-06 26.9 0.0 1.5e-05 25.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KFY01024.1 - 0.022 13.8 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_9 PF08003.6 KFY01024.1 - 0.022 13.4 0.0 0.098 11.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.13 KFY01024.1 - 0.042 12.9 0.0 0.84 8.7 0.0 2.2 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family FAD_binding_3 PF01494.14 KFY01026.1 - 2.7e-13 49.7 0.0 9.4e-08 31.4 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 KFY01026.1 - 0.00046 20.1 0.1 0.0011 18.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFY01026.1 - 0.01 14.7 0.4 0.039 12.8 0.1 2.0 3 0 0 3 3 3 0 FAD binding domain Pyr_redox_2 PF07992.9 KFY01026.1 - 0.014 15.2 0.1 0.027 14.3 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KFY01026.1 - 0.023 14.1 0.1 0.045 13.1 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 KFY01026.1 - 0.025 14.5 0.3 0.41 10.6 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 KFY01026.1 - 0.029 14.1 0.1 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.19 KFY01026.1 - 0.03 13.2 0.1 0.055 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Poxvirus_B22R_C PF13168.1 KFY01026.1 - 0.076 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus B22R protein C-terminal Lycopene_cycl PF05834.7 KFY01026.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 KFY01026.1 - 0.16 12.3 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FSH1 PF03959.8 KFY01028.1 - 4.1e-55 186.5 0.0 5.3e-55 186.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KFY01028.1 - 2.6e-05 24.0 3.1 0.0017 18.1 2.1 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFY01028.1 - 5.1e-05 23.2 5.9 0.59 9.9 2.7 3.8 1 1 1 2 2 2 2 Alpha/beta hydrolase family Esterase_phd PF10503.4 KFY01028.1 - 0.0018 17.5 0.9 0.74 9.0 0.5 2.2 2 0 0 2 2 2 2 Esterase PHB depolymerase Abhydrolase_2 PF02230.11 KFY01028.1 - 0.03 13.7 0.2 13 5.1 0.2 2.9 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase PE-PPE PF08237.6 KFY01028.1 - 0.054 12.9 0.3 0.12 11.7 0.1 1.6 1 1 1 2 2 2 0 PE-PPE domain AXE1 PF05448.7 KFY01028.1 - 0.14 10.6 0.9 0.86 8.0 0.1 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) RPE65 PF03055.10 KFY01029.1 - 7.5e-87 291.9 0.0 1.1e-86 291.3 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF3433 PF11915.3 KFY01029.1 - 5.2e-20 71.4 14.3 1.3e-10 41.2 2.4 3.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) PCI PF01399.22 KFY01029.1 - 2.5e-19 69.5 0.3 6.7e-19 68.1 0.0 1.8 2 0 0 2 2 2 1 PCI domain LMF1 PF06762.9 KFY01029.1 - 0.015 14.1 0.4 0.14 10.9 0.0 2.2 2 0 0 2 2 2 0 Lipase maturation factor Mo-co_dimer PF03404.11 KFY01030.1 - 2.6e-57 192.0 0.0 5.5e-57 191.0 0.0 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 KFY01030.1 - 4.5e-41 140.0 0.0 1.4e-40 138.4 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 KFY01030.1 - 8.9e-30 102.7 0.0 1.5e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KFY01030.1 - 1.6e-25 89.7 0.0 4.9e-25 88.2 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 KFY01030.1 - 9.1e-22 76.6 0.0 1.9e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KFY01030.1 - 0.00085 19.2 0.1 0.14 12.0 0.0 2.4 1 1 0 2 2 2 2 Ferric reductase NAD binding domain NIR_SIR PF01077.17 KFY01031.1 - 1.1e-31 109.3 0.0 2.9e-31 107.9 0.0 1.7 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 KFY01031.1 - 3.3e-30 105.4 0.0 5.7e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFY01031.1 - 8.4e-16 58.1 1.0 1.1e-13 51.4 0.1 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 KFY01031.1 - 6.8e-15 54.6 0.0 1.4e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.10 KFY01031.1 - 2.7e-12 46.5 4.3 1.4e-11 44.2 2.8 2.3 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.12 KFY01031.1 - 3.5e-09 36.1 0.0 1.9e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rieske PF00355.21 KFY01031.1 - 3.9e-09 35.9 0.3 1.3e-08 34.2 0.0 2.0 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 KFY01031.1 - 3.1e-05 24.1 0.0 0.0013 18.8 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFY01031.1 - 0.0041 16.0 1.2 5.4 5.8 0.0 3.7 4 0 0 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KFY01031.1 - 0.016 15.0 2.9 2.4 7.9 0.0 3.4 3 1 1 4 4 4 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KFY01031.1 - 0.046 12.5 2.5 1.1 7.9 0.0 2.8 2 1 1 3 3 3 0 FAD binding domain K_oxygenase PF13434.1 KFY01031.1 - 0.047 12.6 0.0 0.12 11.2 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 KFY01031.1 - 0.18 10.5 2.9 23 3.6 1.5 3.0 2 1 1 3 3 3 0 Glucose inhibited division protein A MFS_1 PF07690.11 KFY01032.1 - 3.6e-27 94.9 26.8 1.5e-24 86.4 7.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.14 KFY01032.1 - 0.00052 18.6 10.0 0.59 8.6 2.1 3.2 2 1 1 3 3 3 3 LacY proton/sugar symporter Kinocilin PF15033.1 KFY01032.1 - 0.054 13.0 0.4 0.13 11.7 0.3 1.6 1 0 0 1 1 1 0 Kinocilin protein Pox_A14 PF05767.7 KFY01032.1 - 0.09 12.7 0.1 0.24 11.3 0.1 1.7 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 GST_N_3 PF13417.1 KFY01033.1 - 7.9e-14 51.6 0.0 1.4e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFY01033.1 - 7.7e-13 48.2 0.0 1.7e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFY01033.1 - 2.9e-09 36.7 0.0 4.2e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFY01033.1 - 4.3e-09 36.4 0.0 9.3e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFY01033.1 - 1.6e-05 24.6 0.0 3e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KFY01033.1 - 7.1e-05 23.2 0.1 0.0001 22.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Lipase_GDSL PF00657.17 KFY01034.1 - 1.1e-08 35.2 1.1 1.7e-08 34.6 0.8 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KFY01034.1 - 1.7e-08 34.7 1.4 2.9e-08 34.0 1.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family VWA_2 PF13519.1 KFY01035.1 - 9.6e-06 25.8 0.0 1.9e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 KFY01035.1 - 0.00072 19.3 5.3 0.00072 19.3 3.7 3.2 4 1 0 4 4 4 1 Ring finger domain VWA PF00092.23 KFY01035.1 - 0.0016 18.2 0.0 0.0032 17.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain FANCL_C PF11793.3 KFY01035.1 - 0.002 18.0 2.6 0.002 18.0 1.8 2.8 3 0 0 3 3 3 1 FANCL C-terminal domain MFS_1 PF07690.11 KFY01036.1 - 6.4e-36 123.7 59.9 4.6e-34 117.6 41.5 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Acetyltransf_1 PF00583.19 KFY01037.1 - 4.1e-08 33.1 0.0 5.9e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFY01037.1 - 2.3e-07 30.8 0.1 3.5e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFY01037.1 - 1.1e-06 28.7 0.6 2.1e-06 27.8 0.4 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFY01037.1 - 0.0035 17.1 0.4 0.76 9.6 0.0 2.7 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 KFY01037.1 - 0.099 11.8 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family FR47 PF08445.5 KFY01037.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Ank_2 PF12796.2 KFY01041.1 - 1.3e-11 44.7 0.0 7.7e-05 22.9 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFY01041.1 - 4.3e-10 38.8 0.0 0.45 10.4 0.0 5.7 4 2 2 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 KFY01041.1 - 1.4e-09 38.1 0.0 0.1 13.1 0.0 5.3 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY01041.1 - 3.5e-07 29.8 1.0 1 9.8 0.0 5.7 6 1 1 7 7 7 3 Ankyrin repeat Ank_2 PF12796.2 KFY01042.1 - 9.1e-22 77.2 0.0 1.9e-09 37.7 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFY01042.1 - 2.3e-18 66.1 0.3 0.0052 17.2 0.0 5.7 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 KFY01042.1 - 8.4e-16 56.9 0.9 0.49 10.2 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 KFY01042.1 - 2.5e-13 48.8 1.6 0.13 12.5 0.0 6.7 6 0 0 6 6 6 2 Ankyrin repeat Epimerase PF01370.16 KFY01042.1 - 5.2e-10 39.1 0.0 8.4e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ank_5 PF13857.1 KFY01042.1 - 2.6e-07 30.6 2.7 0.31 11.3 0.0 4.9 4 2 0 4 4 4 2 Ankyrin repeats (many copies) 3Beta_HSD PF01073.14 KFY01042.1 - 4.5e-07 28.8 0.0 7.5e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFY01042.1 - 9.5e-07 28.9 0.4 2.1e-06 27.8 0.3 1.6 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFY01042.1 - 2.6e-06 26.8 0.3 5.4e-06 25.8 0.2 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KFY01042.1 - 4.9e-05 22.3 0.0 0.00022 20.2 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KFY01042.1 - 0.0043 17.0 0.5 0.012 15.4 0.4 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Ank_2 PF12796.2 KFY01043.1 - 1.9e-42 143.4 0.0 3.6e-12 46.4 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFY01043.1 - 1.5e-29 100.3 11.8 4.8e-06 26.1 0.1 9.6 10 1 0 10 10 10 7 Ankyrin repeat Ank_4 PF13637.1 KFY01043.1 - 6.2e-21 74.3 2.7 0.0002 21.7 0.6 6.8 5 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY01043.1 - 1.8e-20 70.9 7.3 0.0024 17.9 0.1 9.2 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.1 KFY01043.1 - 7.5e-17 60.9 6.2 5.3e-05 23.3 0.1 6.3 5 2 2 7 7 7 4 Ankyrin repeats (many copies) F-box-like PF12937.2 KFY01043.1 - 0.00016 21.3 0.5 0.00061 19.4 0.2 2.0 2 0 0 2 2 2 1 F-box-like MFS_1 PF07690.11 KFY01044.1 - 4.4e-35 121.0 31.0 7.6e-35 120.2 21.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 KFY01045.1 - 3.5e-24 85.0 0.1 6.7e-24 84.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY01045.1 - 5.4e-06 26.2 6.2 9.3e-06 25.4 4.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1445 PF07286.7 KFY01046.1 - 6.9e-57 191.1 0.0 9.1e-57 190.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Hydantoinase_B PF02538.9 KFY01047.1 - 1.3e-195 650.5 0.0 2e-195 650.0 0.0 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 KFY01047.1 - 1.5e-94 316.3 0.4 3.2e-94 315.3 0.1 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KFY01047.1 - 1.3e-52 177.8 2.2 1.4e-51 174.5 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region CoA_binding_2 PF13380.1 KFY01048.1 - 4.7e-28 97.6 0.0 5.8e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain HET PF06985.6 KFY01049.1 - 1.1e-20 74.1 4.8 3.5e-17 62.8 0.2 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Zn_clus PF00172.13 KFY01050.1 - 7.5e-05 22.5 8.7 0.00021 21.1 6.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DSBA PF01323.15 KFY01051.1 - 3.4e-32 111.5 0.0 4.1e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 KFY01051.1 - 0.0003 20.8 0.0 0.001 19.0 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin COesterase PF00135.23 KFY01052.1 - 1e-88 298.3 0.0 1.6e-88 297.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFY01052.1 - 8.8e-06 25.4 0.1 3.1e-05 23.6 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 KFY01052.1 - 0.059 12.2 0.0 0.097 11.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2976 PF11190.3 KFY01052.1 - 0.44 10.1 4.2 0.18 11.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) 5-FTHF_cyc-lig PF01812.15 KFY01053.1 - 5.8e-30 104.4 0.0 7.2e-30 104.1 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Clathrin PF00637.15 KFY01068.1 - 4.5e-22 78.1 5.0 1.4e-20 73.3 1.9 2.5 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.3 KFY01068.1 - 4.7e-08 32.7 0.0 1.2e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-Apc11 PF12861.2 KFY01068.1 - 0.00016 21.4 1.3 0.00037 20.2 0.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KFY01068.1 - 0.00061 19.5 6.7 0.0012 18.6 4.7 1.5 1 0 0 1 1 1 1 Ring finger domain PHD PF00628.24 KFY01068.1 - 0.00065 19.3 4.3 0.0016 18.0 3.0 1.8 1 0 0 1 1 1 1 PHD-finger TPR_14 PF13428.1 KFY01068.1 - 0.00091 19.6 0.3 3.8 8.4 0.0 3.7 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFY01068.1 - 0.0023 17.5 0.3 0.023 14.3 0.0 2.8 2 0 0 2 2 2 1 TPR repeat PHD_2 PF13831.1 KFY01068.1 - 0.0061 15.8 1.3 0.016 14.5 0.9 1.7 1 0 0 1 1 1 1 PHD-finger zf-RING_5 PF14634.1 KFY01068.1 - 0.008 15.8 4.5 0.015 14.9 3.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain TPR_2 PF07719.12 KFY01068.1 - 0.012 15.4 1.0 0.12 12.3 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C3HC4 PF00097.20 KFY01068.1 - 0.044 13.4 5.4 0.085 12.5 3.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFY01068.1 - 0.049 13.7 2.8 0.1 12.7 1.9 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger SPOB_a PF14689.1 KFY01068.1 - 0.2 11.2 2.2 2.5 7.7 0.1 3.0 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_8 PF13181.1 KFY01068.1 - 0.26 11.1 4.3 1.3 8.9 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.1 KFY01068.1 - 0.3 11.1 5.8 0.61 10.1 4.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_12 PF13424.1 KFY01068.1 - 0.46 10.4 5.4 6.7 6.7 0.0 3.7 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFY01068.1 - 0.48 10.7 6.5 18 5.7 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFY01068.1 - 4.1 7.1 6.1 3.7 7.3 0.3 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-C3HC4_4 PF15227.1 KFY01068.1 - 4.7 7.1 5.9 9.3 6.2 4.1 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Band_7 PF01145.20 KFY01069.1 - 4.3e-14 52.8 0.1 4.3e-14 52.8 0.0 3.0 2 1 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KFY01069.1 - 0.025 14.0 0.1 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family WH2 PF02205.15 KFY01075.1 - 1.9e-05 24.0 0.5 4.1e-05 23.0 0.4 1.6 1 0 0 1 1 1 1 WH2 motif CAP_N PF01213.14 KFY01075.1 - 0.0093 15.2 2.0 0.0093 15.2 1.4 3.1 1 1 2 3 3 3 1 Adenylate cyclase associated (CAP) N terminal eIF-1a PF01176.14 KFY01076.1 - 4.4e-28 96.4 0.0 6.2e-28 96.0 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 PTCB-BRCT PF12738.2 KFY01078.1 - 3.2e-11 42.9 0.0 6.5e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KFY01078.1 - 4.1e-08 33.2 0.0 8.4e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 KFY01078.1 - 0.00076 19.5 0.0 0.0025 17.8 0.0 1.9 1 1 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.3 KFY01078.1 - 0.0034 17.1 0.1 0.013 15.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) adh_short PF00106.20 KFY01079.1 - 5.2e-06 26.4 0.0 9.7e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFY01079.1 - 0.0004 20.0 0.0 0.00077 19.1 0.0 1.5 2 0 0 2 2 2 1 KR domain CBM_6 PF03422.10 KFY01079.1 - 0.05 13.7 0.1 0.084 13.0 0.1 1.2 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) SEN1_N PF12726.2 KFY01080.1 - 8.4e-182 605.9 0.8 1.1e-181 605.6 0.5 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 KFY01080.1 - 1.6e-66 224.2 0.3 1.6e-66 224.2 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KFY01080.1 - 5.6e-59 198.8 0.0 1.1e-58 197.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFY01080.1 - 2.1e-10 40.1 0.1 7.1e-10 38.5 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KFY01080.1 - 1e-06 28.4 0.0 0.00065 19.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.16 KFY01080.1 - 1.2e-06 28.0 0.0 0.00028 20.3 0.0 2.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 KFY01080.1 - 2.8e-06 27.0 1.1 0.077 12.5 0.0 4.3 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 KFY01080.1 - 0.0075 15.7 0.1 0.1 12.0 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Hydrolase PF00702.21 KFY01081.1 - 1.3e-13 51.8 3.5 6.5e-12 46.3 2.4 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFY01081.1 - 2.6e-12 47.3 0.0 6.6e-12 46.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFY01081.1 - 7.4e-12 45.0 0.0 2.1e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 KFY01081.1 - 1.1e-11 44.2 0.0 1.1e-11 44.2 0.0 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.7 KFY01081.1 - 0.019 14.5 0.4 0.056 13.0 0.3 1.8 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 KFY01085.1 - 2.7e-30 105.3 14.0 2.7e-30 105.3 9.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY01085.1 - 2e-08 33.2 10.0 2e-08 33.2 6.9 2.2 2 1 1 3 3 3 1 Sugar (and other) transporter DUF791 PF05631.9 KFY01085.1 - 0.00011 20.9 0.5 0.00022 20.0 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_2 PF13347.1 KFY01085.1 - 0.00015 20.3 3.2 0.00015 20.3 2.2 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein BTB PF00651.26 KFY01086.1 - 0.053 13.5 0.0 0.25 11.3 0.0 2.0 1 1 0 1 1 1 0 BTB/POZ domain APH PF01636.18 KFY01087.1 - 2.4e-07 30.7 0.0 4.8e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFY01087.1 - 1.5e-05 24.7 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase DSPc PF00782.15 KFY01088.1 - 7.3e-10 38.5 0.0 1.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KFY01088.1 - 0.00074 18.9 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KFY01088.1 - 0.0049 17.1 0.0 0.0082 16.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Cytochrom_B558a PF05038.8 KFY01093.1 - 0.072 12.7 0.6 0.12 12.0 0.4 1.3 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit DUF2655 PF10848.3 KFY01093.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2655) FAM163 PF15069.1 KFY01093.1 - 0.37 11.3 2.5 0.5 10.9 1.8 1.1 1 0 0 1 1 1 0 FAM163 family Dicty_REP PF05086.7 KFY01093.1 - 6.6 4.3 5.5 6.8 4.3 3.8 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pkinase PF00069.20 KFY01094.1 - 1.1e-09 37.8 0.0 2.5e-09 36.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY01094.1 - 0.04 12.9 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase 4HBT_2 PF13279.1 KFY01096.1 - 6e-07 29.9 0.1 7.6e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF1479 PF07350.7 KFY01107.1 - 1.2e-91 307.3 0.0 1.3e-91 307.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Ceramidase_alk PF04734.8 KFY01108.1 - 2.6e-270 898.0 0.0 2.9e-270 897.8 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase DUF2244 PF10003.4 KFY01108.1 - 0.32 10.3 1.3 0.55 9.6 0.9 1.3 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) FtsJ PF01728.14 KFY01109.1 - 5.5e-63 212.2 0.0 6.8e-63 211.9 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 KFY01109.1 - 2.1e-05 24.2 0.0 4e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY01109.1 - 9.8e-05 22.9 0.0 0.00056 20.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY01109.1 - 0.01 15.4 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain OST3_OST6 PF04756.8 KFY01110.1 - 6.4e-21 74.5 1.3 8.8e-21 74.1 0.9 1.1 1 0 0 1 1 1 1 OST3 / OST6 family DUF2157 PF09925.4 KFY01110.1 - 0.034 13.7 1.0 0.09 12.3 0.7 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) VIT1 PF01988.14 KFY01110.1 - 9.3 5.6 9.5 4.8 6.6 1.3 2.1 1 1 1 2 2 2 0 VIT family Med25_SD1 PF11235.3 KFY01111.1 - 1.9 8.7 8.3 0.15 12.3 0.4 2.3 1 1 1 2 2 2 0 Mediator complex subunit 25 synapsin 1 Membralin PF09746.4 KFY01111.1 - 2 7.3 8.1 2.7 6.9 5.6 1.2 1 0 0 1 1 1 0 Tumour-associated protein Rft-1 PF04506.8 KFY01112.1 - 2.3e-92 310.1 17.9 2.6e-92 309.9 12.4 1.0 1 0 0 1 1 1 1 Rft protein DEAD PF00270.24 KFY01113.1 - 3.4e-51 173.0 0.0 3.1e-49 166.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFY01113.1 - 1.4e-28 98.5 0.0 4.9e-28 96.8 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFY01113.1 - 2.9e-09 37.0 0.5 1.1e-08 35.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KFY01113.1 - 4.3e-09 35.6 0.0 6.2e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain CMS1 PF14617.1 KFY01113.1 - 0.015 14.4 0.0 0.015 14.4 0.0 2.6 2 1 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 KFY01113.1 - 0.033 12.6 0.0 0.16 10.3 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1253) Ycf1 PF05758.7 KFY01113.1 - 0.12 10.1 1.1 0.14 9.8 0.7 1.1 1 0 0 1 1 1 0 Ycf1 RR_TM4-6 PF06459.7 KFY01113.1 - 6.4 6.5 15.1 11 5.8 10.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Rota_VP2 PF05087.7 KFY01113.1 - 7.9 4.2 10.1 11 3.7 7.0 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein NifU_N PF01592.11 KFY01114.1 - 5.5e-51 171.7 0.0 7.4e-51 171.3 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain UCH PF00443.24 KFY01115.1 - 9.3e-43 146.2 0.0 1.4e-42 145.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFY01115.1 - 1.8e-23 82.3 15.4 4.2e-19 68.4 2.1 3.6 3 1 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 KFY01115.1 - 8.4e-22 76.3 0.5 6.3e-11 41.7 0.0 2.8 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 KFY01115.1 - 1.2e-17 64.3 0.0 8e-17 61.6 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.1 KFY01115.1 - 0.043 13.3 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain DUF2180 PF09947.4 KFY01115.1 - 8.9 6.1 10.2 18 5.1 0.2 4.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) Rax2 PF12768.2 KFY01116.1 - 3e-94 315.3 3.2 4.8e-85 285.1 0.0 4.4 4 0 0 4 4 4 3 Cortical protein marker for cell polarity Kelch_3 PF13415.1 KFY01116.1 - 0.0011 19.0 1.7 0.32 11.2 0.2 4.6 4 0 0 4 4 4 1 Galactose oxidase, central domain SNase PF00565.12 KFY01117.1 - 2.8e-23 82.2 0.1 4.2e-23 81.6 0.1 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue P34-Arc PF04045.9 KFY01118.1 - 7.9e-102 339.6 0.4 9.7e-102 339.3 0.3 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 KFY01118.1 - 0.0053 16.1 0.1 0.011 15.1 0.1 1.5 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Radical_SAM PF04055.16 KFY01118.1 - 0.062 13.4 1.4 4 7.5 0.0 2.6 1 1 0 2 2 2 0 Radical SAM superfamily WD40 PF00400.27 KFY01119.1 - 2.7e-67 220.4 26.2 2.6e-08 33.4 0.1 11.6 12 0 0 12 12 12 10 WD domain, G-beta repeat APH PF01636.18 KFY01119.1 - 3.3e-38 131.7 0.0 6.2e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Utp12 PF04003.7 KFY01119.1 - 7.1e-21 74.1 1.5 1.4e-20 73.2 1.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 KFY01119.1 - 0.00018 19.7 2.6 0.013 13.7 0.0 3.9 4 1 1 5 5 5 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFY01119.1 - 0.00057 18.7 1.5 3 6.5 0.1 4.5 2 2 3 5 5 5 2 Nup133 N terminal like EcKinase PF02958.15 KFY01119.1 - 0.0034 16.5 0.0 0.0069 15.5 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.9 KFY01119.1 - 0.0052 15.8 0.0 0.029 13.3 0.0 2.1 1 1 0 1 1 1 1 Fructosamine kinase RIO1 PF01163.17 KFY01119.1 - 0.011 15.0 0.0 0.12 11.7 0.0 2.4 2 0 0 2 2 2 0 RIO1 family DUF1679 PF07914.6 KFY01119.1 - 0.014 14.0 0.0 0.045 12.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) eIF2A PF08662.6 KFY01119.1 - 0.066 12.9 0.0 0.85 9.2 0.0 2.8 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A HECT PF00632.20 KFY01124.1 - 6.2e-71 239.1 0.0 9e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C1_1 PF00130.17 KFY01124.1 - 0.02 14.5 0.4 0.048 13.3 0.3 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MMR_HSR1 PF01926.18 KFY01125.1 - 6.5e-05 22.8 0.0 0.00038 20.3 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase Cytochrome-c551 PF10643.4 KFY01125.1 - 0.23 10.7 0.1 0.39 9.9 0.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Ribosomal_L16 PF00252.13 KFY01126.1 - 6.3e-28 97.1 0.1 8.1e-28 96.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.7 KFY01127.1 - 3.9e-58 195.6 0.2 8.4e-57 191.2 0.0 2.5 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 KFY01127.1 - 1.8e-13 50.4 0.0 4.6e-13 49.1 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 KFY01127.1 - 3.9e-08 33.5 0.1 1.9e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KFY01127.1 - 1.7e-06 27.0 0.0 2.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KFY01127.1 - 1.2e-05 25.4 0.0 4.4e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFY01127.1 - 1.6e-05 25.7 1.6 6.6e-05 23.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 KFY01127.1 - 0.0029 17.9 0.0 0.0029 17.9 0.0 3.4 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.1 KFY01127.1 - 0.0032 17.0 0.0 0.0078 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFY01127.1 - 0.004 17.1 0.9 0.035 14.1 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_14 PF13173.1 KFY01127.1 - 0.0077 16.1 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KFY01127.1 - 0.008 16.1 0.1 0.052 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta PF06144.8 KFY01127.1 - 0.013 14.9 0.0 0.036 13.5 0.0 1.8 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_19 PF13245.1 KFY01127.1 - 0.019 14.6 0.0 0.059 13.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain PTCB-BRCT PF12738.2 KFY01127.1 - 0.096 12.5 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain Muted PF14942.1 KFY01127.1 - 0.7 9.7 7.4 0.26 11.1 2.5 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Arch_ATPase PF01637.13 KFY01127.1 - 2.9 7.5 7.5 7.9 6.0 1.0 3.2 2 1 0 2 2 2 0 Archaeal ATPase DUF1476 PF07345.6 KFY01128.1 - 0.017 15.3 3.0 0.097 12.9 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1476) tRNA-synt_2d PF01409.15 KFY01129.1 - 5.8e-47 159.9 0.9 3.3e-24 85.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) GrpE PF01025.14 KFY01129.1 - 3e-44 150.5 4.7 5.7e-44 149.5 3.3 1.4 1 0 0 1 1 1 1 GrpE FDX-ACB PF03147.9 KFY01129.1 - 4e-26 91.0 0.0 1.1e-25 89.6 0.0 1.8 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain DUF2222 PF09984.4 KFY01129.1 - 0.08 12.3 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized signal transduction histidine kinase domain (DUF2222) Mito_carr PF00153.22 KFY01130.1 - 9.5e-63 207.9 1.1 2.7e-21 75.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_A_bac PF01000.21 KFY01131.1 - 2.4e-32 111.3 0.0 4.3e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KFY01131.1 - 2e-14 52.4 0.0 2.6e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Cluap1 PF10234.4 KFY01146.1 - 0.0055 15.9 2.8 0.0083 15.3 1.9 1.2 1 0 0 1 1 1 1 Clusterin-associated protein-1 GAS PF13851.1 KFY01146.1 - 0.027 13.6 6.5 0.02 14.1 3.4 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding FbpA PF05833.6 KFY01146.1 - 0.037 12.5 0.3 0.037 12.5 0.2 1.9 2 0 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) NuiA PF07924.6 KFY01146.1 - 0.051 13.4 0.1 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein DUF3618 PF12277.3 KFY01146.1 - 0.067 13.2 2.3 0.2 11.6 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3618) DUF2713 PF10897.3 KFY01146.1 - 0.079 12.2 0.3 0.11 11.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) Prismane PF03063.15 KFY01146.1 - 0.088 11.1 0.5 0.11 10.7 0.3 1.0 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Nup88 PF10168.4 KFY01146.1 - 0.11 10.3 2.5 0.15 9.8 1.7 1.1 1 0 0 1 1 1 0 Nuclear pore component Nnf1 PF03980.9 KFY01146.1 - 0.3 11.0 5.5 0.11 12.5 1.7 1.8 2 0 0 2 2 2 0 Nnf1 Atg14 PF10186.4 KFY01146.1 - 2.2 7.1 6.3 1.2 7.9 2.9 1.6 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ECM11 PF15463.1 KFY01146.1 - 2.6 8.3 7.6 1.2 9.3 2.1 2.0 2 0 0 2 2 2 0 Extracellular mutant protein 11 BEX PF04538.7 KFY01146.1 - 3.4 7.9 7.2 0.97 9.6 0.4 2.4 2 1 0 2 2 2 0 Brain expressed X-linked like family DUF1657 PF07870.6 KFY01146.1 - 4.2 7.1 5.2 13 5.5 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1657) KfrA_N PF11740.3 KFY01146.1 - 4.4 7.7 8.6 0.86 10.0 0.3 2.3 2 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term FliT PF05400.8 KFY01146.1 - 5.7 7.4 11.1 2.1e+02 2.4 7.7 2.5 1 1 0 1 1 1 0 Flagellar protein FliT Laminin_I PF06008.9 KFY01146.1 - 9.5 5.4 11.4 0.95 8.7 1.1 2.1 1 1 1 2 2 2 0 Laminin Domain I NeuB PF03102.9 KFY01147.1 - 0.0026 16.9 0.2 0.04 13.0 0.0 2.3 2 0 0 2 2 2 1 NeuB family Ret_tiss PF10044.4 KFY01147.1 - 0.033 14.7 1.2 6.5 7.3 0.0 4.0 4 0 0 4 4 4 0 Retinal tissue protein Zn_clus PF00172.13 KFY01149.1 - 1.2e-13 50.6 46.0 1e-05 25.3 9.6 3.5 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain Tropomyosin_1 PF12718.2 KFY01150.1 - 0.057 13.2 0.2 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Tropomyosin like DUF2215 PF10225.4 KFY01151.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Pkinase PF00069.20 KFY01152.1 - 1.1e-26 93.5 0.0 1.5e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY01152.1 - 3.3e-25 88.6 0.0 4.7e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFY01152.1 - 0.00012 21.2 0.0 0.00016 20.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFY01152.1 - 0.025 13.6 0.0 0.037 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Chromo PF00385.19 KFY01153.1 - 2.2e-15 56.0 5.3 2.5e-07 30.2 0.5 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 KFY01153.1 - 0.36 10.7 1.6 1.3 9.0 0.1 2.2 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 CBM_1 PF00734.13 KFY01162.1 - 1.6e-09 37.2 13.7 1.6e-09 37.2 9.5 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain FAD_binding_3 PF01494.14 KFY01163.1 - 1.1e-79 268.1 0.0 1.4e-79 267.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KFY01163.1 - 8.1e-49 165.4 0.0 1.6e-48 164.5 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.19 KFY01163.1 - 2.7e-05 23.1 0.1 0.00043 19.2 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KFY01163.1 - 4e-05 22.8 0.2 7.9e-05 21.9 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KFY01163.1 - 0.00096 18.3 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KFY01163.1 - 0.001 18.0 0.3 0.011 14.7 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFY01163.1 - 0.0031 17.4 0.1 0.01 15.7 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KFY01163.1 - 0.013 14.1 0.1 0.02 13.5 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase SE PF08491.5 KFY01163.1 - 0.014 14.2 0.0 1.6 7.5 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_8 PF13450.1 KFY01163.1 - 0.075 13.0 0.2 0.27 11.2 0.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain PsbN PF02468.10 KFY01164.1 - 0.014 14.9 0.1 0.03 13.9 0.1 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) DUF3435 PF11917.3 KFY01170.1 - 0.0043 15.8 0.1 0.0043 15.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) UBN2 PF14223.1 KFY01170.1 - 0.096 12.4 0.1 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Med7 PF05983.6 KFY01170.1 - 0.11 12.2 0.6 3.1 7.5 0.0 2.1 2 0 0 2 2 2 0 MED7 protein Sec16_C PF12931.2 KFY01177.1 - 9.3e-96 320.8 0.0 1.4e-95 320.3 0.0 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 KFY01177.1 - 1.6e-32 111.9 0.0 3.3e-32 110.8 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region NYD-SP28_assoc PF14775.1 KFY01177.1 - 0.5 10.0 0.2 26 4.5 0.0 2.4 2 0 0 2 2 2 0 Sperm tail C-terminal domain Hydrolase PF00702.21 KFY01178.1 - 1.8e-17 64.4 0.0 1.5e-16 61.4 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFY01178.1 - 3.9e-14 52.2 0.0 2.1e-13 49.8 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KFY01178.1 - 3.8e-10 40.2 0.4 1e-09 38.8 0.3 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFY01178.1 - 0.00021 21.2 0.0 0.00072 19.4 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFY01178.1 - 0.0008 19.0 0.0 0.0016 18.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase 2-Hacid_dh_C PF02826.14 KFY01179.1 - 2.2e-50 170.2 0.0 4.4e-50 169.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFY01179.1 - 7.2e-15 54.6 0.0 1.2e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Methyltransf_26 PF13659.1 KFY01179.1 - 2.5e-14 53.2 0.0 1.5e-13 50.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY01179.1 - 2.4e-11 44.2 0.0 1.1e-09 38.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY01179.1 - 1.6e-10 40.7 0.0 1.5e-08 34.4 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY01179.1 - 6.4e-07 29.6 0.0 4.3e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KFY01179.1 - 6.8e-07 28.8 0.0 0.00028 20.3 0.0 3.2 2 1 1 3 3 3 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KFY01179.1 - 0.0014 19.0 0.0 0.006 17.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY01179.1 - 0.0045 17.4 0.0 0.063 13.7 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain N6_Mtase PF02384.11 KFY01179.1 - 0.015 14.3 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_23 PF13489.1 KFY01179.1 - 0.029 14.1 0.0 0.095 12.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 KFY01179.1 - 0.11 11.6 0.0 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Suc_Fer-like PF06999.7 KFY01180.1 - 4.8e-23 82.3 0.0 6.1e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DSPc PF00782.15 KFY01189.1 - 8.6e-25 86.8 0.0 1.2e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 KFY01189.1 - 0.00023 20.1 0.0 0.00032 19.6 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Mu-like_Com PF10122.4 KFY01189.1 - 0.025 13.6 0.4 0.063 12.3 0.3 1.7 1 0 0 1 1 1 0 Mu-like prophage protein Com Y_phosphatase3 PF13350.1 KFY01189.1 - 0.036 14.2 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KFY01189.1 - 0.081 12.9 0.0 0.23 11.5 0.0 1.6 2 0 0 2 2 2 0 Inositol hexakisphosphate Ndc1_Nup PF09531.5 KFY01190.1 - 8.7e-147 490.1 0.0 1e-146 489.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup zf-C2H2_4 PF13894.1 KFY01197.1 - 0.00076 19.6 1.6 0.0016 18.6 1.1 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-Di19 PF05605.7 KFY01197.1 - 0.0056 16.7 2.5 0.0098 16.0 1.7 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KFY01197.1 - 0.037 14.3 1.6 0.068 13.5 1.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Creb_binding PF09030.5 KFY01197.1 - 0.094 12.9 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Creb binding AAA PF00004.24 KFY01209.1 - 4e-48 162.9 0.0 9.6e-43 145.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KFY01209.1 - 2.7e-05 23.6 0.2 0.00017 21.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KFY01209.1 - 3e-05 23.1 0.0 0.0005 19.1 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KFY01209.1 - 8.8e-05 23.3 0.0 0.0017 19.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 KFY01209.1 - 0.00041 19.3 0.0 0.00078 18.3 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 IstB_IS21 PF01695.12 KFY01209.1 - 0.00077 18.9 0.0 0.0019 17.6 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 KFY01209.1 - 0.0011 19.0 0.5 0.0082 16.2 0.0 2.7 2 1 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 KFY01209.1 - 0.0015 18.6 0.0 0.0095 16.0 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 KFY01209.1 - 0.0025 17.8 4.3 0.021 14.8 0.0 3.8 4 1 1 5 5 5 1 AAA ATPase domain AAA_19 PF13245.1 KFY01209.1 - 0.0038 16.9 1.0 0.018 14.7 0.0 2.7 3 0 0 3 3 2 1 Part of AAA domain AAA_2 PF07724.9 KFY01209.1 - 0.004 17.0 0.0 0.01 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 KFY01209.1 - 0.0088 14.8 0.0 0.014 14.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus KaiC PF06745.8 KFY01209.1 - 0.016 14.2 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 KaiC Mg_chelatase PF01078.16 KFY01209.1 - 0.017 14.2 0.0 0.037 13.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KFY01209.1 - 0.021 14.5 0.0 0.081 12.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PhoH PF02562.11 KFY01209.1 - 0.029 13.6 0.0 0.067 12.4 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.1 KFY01209.1 - 0.041 14.2 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFY01209.1 - 0.041 13.7 0.0 0.27 11.1 0.0 2.5 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.1 KFY01209.1 - 0.062 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KFY01209.1 - 0.08 12.5 0.1 0.2 11.1 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KFY01209.1 - 0.088 12.7 0.0 0.29 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain PPV_E1_C PF00519.12 KFY01209.1 - 0.21 10.1 0.0 0.34 9.4 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase HATPase_c_2 PF13581.1 KFY01210.1 - 0.0019 17.9 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain BTB PF00651.26 KFY01211.1 - 3.5e-05 23.7 0.9 0.11 12.5 0.1 3.1 2 1 1 3 3 3 2 BTB/POZ domain Alpha-amylase PF00128.19 KFY01212.1 - 1.1e-64 218.8 0.0 1.5e-64 218.3 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KFY01212.1 - 5.9e-23 80.7 0.0 1.4e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) IlvC PF01450.14 KFY01212.1 - 0.0093 15.9 0.0 0.87 9.5 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain Aminotran_5 PF00266.14 KFY01212.1 - 0.083 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Hydrolase_3 PF08282.7 KFY01213.1 - 9.8e-13 48.2 0.0 5.4e-12 45.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PMM PF03332.8 KFY01213.1 - 3.2e-10 39.9 0.0 3.9e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase S6PP PF05116.8 KFY01213.1 - 0.015 14.5 0.0 0.085 12.1 0.0 2.0 2 1 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Trehalose_PPase PF02358.11 KFY01213.1 - 0.025 13.4 0.0 0.037 12.9 0.0 1.4 1 1 0 1 1 1 0 Trehalose-phosphatase adh_short_C2 PF13561.1 KFY01214.1 - 8.9e-24 84.5 0.1 1.3e-23 84.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFY01214.1 - 2.6e-16 59.9 7.4 4e-16 59.3 5.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase APH PF01636.18 KFY01215.1 - 1.2e-13 51.3 0.0 1.8e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFY01215.1 - 6.1e-08 32.4 0.0 1.5e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase Amidohydro_2 PF04909.9 KFY01216.1 - 2.4e-14 53.5 0.0 2.6e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase TPR_11 PF13414.1 KFY01224.1 - 4.2e-22 77.5 8.6 2.1e-09 36.8 0.7 4.4 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 KFY01224.1 - 1.7e-21 74.8 1.7 2.2e-05 23.8 0.0 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 KFY01224.1 - 3.8e-19 66.9 6.4 7e-05 22.4 0.0 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFY01224.1 - 5.8e-16 57.5 7.4 0.00033 21.0 0.4 6.6 5 2 2 7 7 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 KFY01224.1 - 2.1e-14 53.1 8.3 1.9e-08 34.1 0.0 4.3 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFY01224.1 - 3.1e-13 50.0 6.7 0.0003 21.3 0.3 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFY01224.1 - 1.1e-12 48.0 6.9 0.0065 16.7 0.0 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFY01224.1 - 5.3e-11 41.4 0.3 0.0036 16.9 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFY01224.1 - 1.8e-10 40.1 1.4 0.46 10.8 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFY01224.1 - 2e-09 36.5 8.1 0.0033 17.0 0.1 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.1 KFY01224.1 - 9.8e-08 32.0 5.8 0.0036 17.3 0.0 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KFY01224.1 - 3.3e-07 30.3 1.2 2.9e-05 24.1 0.1 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KFY01224.1 - 4.2e-06 26.5 6.7 0.0049 16.6 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat CRISPR_Cse2 PF09485.5 KFY01224.1 - 0.00025 21.1 0.8 0.0018 18.3 0.1 2.4 2 0 0 2 2 2 1 CRISPR-associated protein Cse2 (CRISPR_cse2) TPR_10 PF13374.1 KFY01224.1 - 0.0027 17.5 5.2 0.15 12.0 0.3 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_3 PF07720.7 KFY01224.1 - 0.0049 16.6 0.0 7.8 6.4 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 KFY01224.1 - 0.016 14.2 1.5 3.4 6.6 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KFY01224.1 - 0.017 15.5 10.2 18 6.0 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat NatB_MDM20 PF09797.4 KFY01224.1 - 0.077 11.7 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit Glyco_hydro_16 PF00722.16 KFY01225.1 - 5.4e-10 38.8 0.1 6.6e-09 35.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF4070 PF13282.1 KFY01238.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4070) XFP_N PF09364.5 KFY01239.1 - 8.9e-178 590.6 0.0 1.2e-177 590.1 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 KFY01239.1 - 1.3e-87 292.5 0.0 1.8e-87 292.0 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.10 KFY01239.1 - 4.9e-80 267.3 0.0 1e-79 266.3 0.0 1.5 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase E1_dh PF00676.15 KFY01239.1 - 0.16 10.6 0.0 1.4 7.5 0.0 2.1 2 0 0 2 2 2 0 Dehydrogenase E1 component Fructosamin_kin PF03881.9 KFY01240.1 - 8.7e-22 77.4 0.0 1.1e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase Sugar_tr PF00083.19 KFY01241.1 - 4.4e-112 374.9 26.9 5.4e-112 374.6 18.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY01241.1 - 4.7e-16 58.4 38.0 8.9e-12 44.3 11.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GFA PF04828.9 KFY01241.1 - 7.2e-14 51.5 0.1 5.5e-07 29.4 0.0 2.8 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 KFY01241.1 - 0.0008 18.8 2.0 0.96 9.0 0.1 2.6 2 0 0 2 2 2 2 NADH pyrophosphatase zinc ribbon domain Nudix_N_2 PF14803.1 KFY01241.1 - 0.14 11.8 4.3 3.9 7.2 0.2 3.1 3 0 0 3 3 3 0 Nudix N-terminal Auto_anti-p27 PF06677.7 KFY01241.1 - 0.28 10.9 3.3 6.8 6.5 0.2 2.8 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zinc_ribbon_2 PF13240.1 KFY01241.1 - 0.35 10.3 8.9 0.32 10.5 0.7 3.2 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 KFY01241.1 - 5.2 6.4 16.0 5.5 6.3 4.8 3.1 3 1 0 3 3 3 0 zinc-ribbon domain Glyco_hydro_92 PF07971.7 KFY01242.1 - 1.3e-166 555.1 0.2 1.7e-166 554.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 AA_permease_2 PF13520.1 KFY01243.1 - 5.4e-84 282.1 43.8 6.7e-84 281.8 30.4 1.1 1 0 0 1 1 1 1 Amino acid permease UCR_Fe-S_N PF10399.4 KFY01243.1 - 0.13 11.4 1.3 0.42 9.8 0.9 1.9 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal MFS_1 PF07690.11 KFY01244.1 - 2.7e-20 72.4 47.9 4.2e-18 65.1 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY01244.1 - 4.7e-12 45.2 18.3 1.2e-11 43.9 12.7 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter LRR_4 PF12799.2 KFY01245.1 - 5.3e-32 108.8 29.3 3.1e-06 26.6 0.3 8.4 8 0 0 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFY01245.1 - 7.9e-27 92.7 33.6 3.8e-07 29.7 2.8 7.4 4 2 4 8 8 8 8 Leucine rich repeat LRR_1 PF00560.28 KFY01245.1 - 2.6e-10 38.8 34.8 0.2 11.8 0.3 12.4 12 2 2 14 14 14 5 Leucine Rich Repeat LRR_9 PF14580.1 KFY01245.1 - 4.5e-08 32.8 9.0 8.6e-05 22.1 0.3 3.7 2 1 2 4 4 4 3 Leucine-rich repeat LRR_7 PF13504.1 KFY01245.1 - 3.8e-06 26.2 43.3 0.3 11.4 0.2 11.4 13 0 0 13 13 13 5 Leucine rich repeat LRR_6 PF13516.1 KFY01245.1 - 0.0014 18.4 35.5 0.032 14.3 0.4 10.1 10 2 2 12 12 12 2 Leucine Rich repeat DUF4407 PF14362.1 KFY01245.1 - 0.1 11.5 1.2 0.22 10.4 0.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Tubulin PF00091.20 KFY01246.1 - 2.9e-66 223.3 0.0 3.9e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFY01246.1 - 2.4e-45 153.6 0.0 3.8e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KFY01246.1 - 0.0013 18.2 0.0 0.0027 17.2 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tim17 PF02466.14 KFY01247.1 - 8.1e-26 90.5 1.9 1.2e-25 90.0 1.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Brix PF04427.13 KFY01248.1 - 8e-38 130.0 0.1 1.1e-37 129.5 0.1 1.2 1 0 0 1 1 1 1 Brix domain Sugar_tr PF00083.19 KFY01250.1 - 3.6e-77 259.8 26.4 4.4e-77 259.5 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY01250.1 - 7.2e-33 113.7 27.0 1.5e-28 99.5 13.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFY01250.1 - 5.1e-05 21.6 2.5 8.3e-05 20.9 1.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Hydrophobin_2 PF06766.6 KFY01251.1 - 0.032 13.9 6.1 0.11 12.2 4.3 1.8 1 1 0 1 1 1 0 Fungal hydrophobin Orexin PF02072.10 KFY01251.1 - 0.23 11.2 1.3 7.9 6.2 0.1 2.1 2 0 0 2 2 2 0 Prepro-orexin DUF3948 PF13134.1 KFY01251.1 - 0.28 10.7 1.4 0.4 10.2 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) zf-GRF PF06839.7 KFY01251.1 - 0.58 10.1 4.6 7.7 6.5 0.2 2.3 1 1 1 2 2 2 0 GRF zinc finger Herpes_gE PF02480.11 KFY01252.1 - 0.027 12.7 0.0 0.041 12.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RgpF PF05045.7 KFY01253.1 - 0.0037 15.8 0.1 0.067 11.7 0.0 2.0 2 0 0 2 2 2 2 Rhamnan synthesis protein F RNA_pol_I_A49 PF06870.7 KFY01254.1 - 7.4e-76 255.2 0.7 9.9e-76 254.7 0.5 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor HDOD PF08668.7 KFY01254.1 - 0.024 13.8 0.0 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 HDOD domain Ribosomal_L41 PF05162.8 KFY01255.1 - 2.8e-07 30.0 26.4 2.8e-07 30.0 18.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L41 Pkinase PF00069.20 KFY01256.1 - 1.3e-60 204.8 0.8 1e-59 201.8 0.0 2.7 3 0 0 3 3 3 1 Protein kinase domain SAC3_GANP PF03399.11 KFY01256.1 - 4.2e-45 153.8 1.5 6.9e-45 153.1 0.7 1.6 2 0 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Pkinase_Tyr PF07714.12 KFY01256.1 - 1.4e-26 93.1 0.0 2.9e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KFY01256.1 - 6.1e-09 35.8 0.0 1.4e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KFY01256.1 - 0.00016 20.7 0.0 0.00041 19.4 0.0 1.7 1 0 0 1 1 1 1 Kinase-like PCI_Csn8 PF10075.4 KFY01256.1 - 0.011 15.4 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 YrbL-PhoP_reg PF10707.4 KFY01256.1 - 1.2 8.4 4.6 0.21 10.8 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DKCLD PF08068.7 KFY01257.1 - 2.7e-29 100.8 0.1 1.6e-28 98.4 0.1 2.2 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 KFY01257.1 - 3.1e-24 85.8 0.3 2.9e-21 76.1 0.2 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 KFY01257.1 - 1.7e-21 75.7 1.2 3.3e-21 74.7 0.9 1.5 1 0 0 1 1 1 1 PUA domain RNA_polI_A34 PF08208.6 KFY01257.1 - 0.086 12.4 26.2 0.14 11.7 18.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RNase_H2-Ydr279 PF09468.5 KFY01257.1 - 1.3 8.1 12.2 2.1 7.4 8.5 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Med19 PF10278.4 KFY01257.1 - 9.5 5.8 20.2 24 4.5 14.0 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Bac_rhamnosid PF05592.6 KFY01259.1 - 1.7e-20 72.7 0.6 3.8e-11 41.8 0.0 3.1 3 0 0 3 3 3 3 Bacterial alpha-L-rhamnosidase LtrA PF06772.6 KFY01259.1 - 1.2e-18 67.1 16.2 2.2e-18 66.3 11.2 1.3 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF608 PF04685.8 KFY01259.1 - 0.00026 19.8 1.2 0.00042 19.1 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 GDE_C PF06202.9 KFY01259.1 - 0.017 13.8 0.2 0.029 13.1 0.2 1.2 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Trehalase PF01204.13 KFY01259.1 - 0.042 12.4 0.0 0.065 11.8 0.0 1.1 1 0 0 1 1 1 0 Trehalase Amidase PF01425.16 KFY01262.1 - 5.7e-75 252.8 0.3 7.8e-71 239.2 1.4 2.1 1 1 1 2 2 2 2 Amidase zf-PARP PF00645.13 KFY01263.1 - 7.5e-19 67.7 0.1 1.9e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Dynactin_p62 PF05502.8 KFY01264.1 - 9.3e-126 420.4 0.6 1.1e-125 420.1 0.4 1.1 1 0 0 1 1 1 1 Dynactin p62 family Lipase_GDSL_2 PF13472.1 KFY01265.1 - 1.2e-06 28.7 1.1 2.6e-06 27.6 0.1 2.0 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFY01265.1 - 8.8e-05 22.4 5.1 0.0012 18.6 3.5 2.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KFY01265.1 - 0.13 11.9 0.0 20 4.8 0.0 2.3 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family ADH_N PF08240.7 KFY01266.1 - 3.8e-26 90.9 2.6 5.8e-26 90.3 1.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFY01266.1 - 1.1e-12 47.6 0.0 1.8e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KFY01266.1 - 0.0034 16.5 0.1 0.0059 15.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1273 PF06908.6 KFY01266.1 - 0.032 13.9 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) DUF4489 PF14879.1 KFY01266.1 - 0.11 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4489) DUF829 PF05705.9 KFY01267.1 - 3.1e-50 171.1 0.1 3.6e-50 170.9 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) ATP_transf PF09830.4 KFY01268.1 - 4.9e-16 58.2 0.0 8.2e-16 57.5 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase PA14_2 PF10528.4 KFY01269.1 - 3.7e-26 91.3 0.7 2.3e-13 50.0 0.0 2.4 2 0 0 2 2 2 2 GLEYA domain PA14 PF07691.7 KFY01269.1 - 1.7e-06 27.7 0.3 0.0035 16.9 0.0 2.3 2 0 0 2 2 2 2 PA14 domain PAN_1 PF00024.21 KFY01269.1 - 4.4e-06 26.3 0.5 4.4e-06 26.3 0.3 1.8 2 0 0 2 2 2 1 PAN domain PAN_4 PF14295.1 KFY01269.1 - 0.0024 17.5 3.9 0.012 15.3 2.7 2.3 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 KFY01269.1 - 0.0095 15.5 2.4 0.026 14.1 1.7 1.7 1 0 0 1 1 1 1 PAN-like domain MFS_1 PF07690.11 KFY01270.1 - 1.8e-14 53.2 18.4 4.3e-14 51.9 12.8 1.6 1 0 0 1 1 1 1 Major Facilitator Superfamily Oxidored_molyb PF00174.14 KFY01271.1 - 3.3e-45 153.5 0.0 6.3e-45 152.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain TauD PF02668.11 KFY01271.1 - 6e-44 150.6 0.1 8.8e-44 150.0 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Mo-co_dimer PF03404.11 KFY01271.1 - 1.9e-23 82.5 4.4 5.2e-23 81.1 3.0 1.8 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain WD40 PF00400.27 KFY01272.1 - 5.3e-41 137.0 21.3 8.5e-09 34.9 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.2 KFY01272.1 - 1.7e-10 40.4 0.0 3.2e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 KFY01272.1 - 6.1e-07 27.9 0.7 0.014 13.6 0.0 3.4 2 1 1 3 3 3 2 Nucleoporin Nup120/160 F-box PF00646.28 KFY01272.1 - 1.6e-05 24.4 0.0 3.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain DASH_Dam1 PF08653.5 KFY01272.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Dam1 FlaG PF03646.10 KFY01272.1 - 0.21 11.7 0.0 1.2 9.3 0.0 2.2 2 0 0 2 2 2 0 FlaG protein hDGE_amylase PF14701.1 KFY01276.1 - 8.1e-179 594.9 0.0 1e-178 594.5 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 KFY01276.1 - 9.3e-114 379.9 0.0 1.4e-113 379.4 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 KFY01276.1 - 5.9e-85 284.5 0.0 9.1e-85 283.9 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 KFY01276.1 - 2.1e-25 88.3 0.0 4.9e-25 87.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 KFY01276.1 - 9.8e-07 28.4 0.0 0.00065 19.1 0.0 2.3 2 0 0 2 2 2 2 Alpha amylase, catalytic domain YCII PF03795.9 KFY01276.1 - 0.11 12.7 0.0 0.6 10.3 0.0 2.2 2 0 0 2 2 2 0 YCII-related domain DAHP_synth_1 PF00793.15 KFY01277.1 - 6.4e-99 330.0 0.0 8.4e-99 329.6 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family Autophagy_act_C PF03987.10 KFY01278.1 - 1.6e-12 47.4 0.2 2.6e-12 46.7 0.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Cytochrom_C1 PF02167.10 KFY01279.1 - 2.9e-82 275.5 0.0 3.7e-82 275.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 KFY01279.1 - 0.015 15.4 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III DUF1515 PF07439.6 KFY01279.1 - 0.11 12.2 0.3 0.24 11.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) HhH-GPD PF00730.20 KFY01280.1 - 0.00032 20.9 0.0 0.001 19.3 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein PBD PF00786.23 KFY01280.1 - 0.043 14.2 0.1 0.28 11.6 0.1 2.5 1 0 0 1 1 1 0 P21-Rho-binding domain MFS_1 PF07690.11 KFY01308.1 - 5.9e-43 146.9 61.4 3.7e-36 124.5 26.4 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFY01308.1 - 7.7e-12 44.2 21.7 1.1e-11 43.6 15.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KFY01308.1 - 1.9e-11 43.2 9.7 1.9e-11 43.2 6.8 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 KFY01308.1 - 0.054 13.2 8.6 0.22 11.3 0.4 3.3 3 0 0 3 3 3 0 MFS_1 like family Lamprin PF06403.6 KFY01309.1 - 0.28 10.9 0.9 0.39 10.4 0.6 1.1 1 0 0 1 1 1 0 Lamprin BUD22 PF09073.5 KFY01310.1 - 0.23 10.4 26.7 0.28 10.2 18.5 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.7 KFY01310.1 - 0.76 8.9 30.1 0.95 8.6 20.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 KFY01310.1 - 3.9 5.2 32.4 4.9 4.9 22.5 1.2 1 0 0 1 1 1 0 Nop14-like family Abhydrolase_6 PF12697.2 KFY01311.1 - 1.1e-11 45.1 2.8 1.7e-11 44.4 2.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFY01311.1 - 1.1e-09 38.2 0.2 1.7e-09 37.5 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KFY01311.1 - 0.00062 19.4 0.1 0.00087 18.9 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KFY01311.1 - 0.018 14.6 0.1 0.024 14.1 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KFY01311.1 - 0.043 13.6 0.2 0.1 12.4 0.2 1.7 1 1 0 1 1 1 0 Putative lysophospholipase BLOC1_2 PF10046.4 KFY01313.1 - 0.053 13.6 0.9 0.067 13.3 0.6 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ank_4 PF13637.1 KFY01314.1 - 9.3e-12 45.1 0.2 4.4e-06 27.0 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY01314.1 - 3.3e-09 36.7 0.1 6e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFY01314.1 - 5.1e-09 36.3 0.1 9.7e-09 35.4 0.1 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFY01314.1 - 3.2e-06 26.6 0.0 0.0039 16.9 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 KFY01314.1 - 0.0017 18.3 0.0 0.084 13.1 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat DUF4401 PF14351.1 KFY01315.1 - 0.0056 15.7 4.2 0.0056 15.7 2.9 2.0 2 1 1 3 3 3 1 Domain of unknown function (DUF4401) Ank_2 PF12796.2 KFY01316.1 - 3.8e-27 94.4 0.4 4.8e-15 55.6 0.0 3.1 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFY01316.1 - 6.4e-23 79.3 3.6 6.8e-07 28.7 0.0 5.9 6 1 1 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 KFY01316.1 - 4.7e-17 62.0 0.1 2.4e-09 37.4 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY01316.1 - 5.9e-17 60.0 1.4 0.00026 20.9 0.0 5.5 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 KFY01316.1 - 1.5e-13 50.5 1.6 1.6e-05 24.9 0.1 4.8 3 2 2 5 5 5 3 Ankyrin repeats (many copies) F-box-like PF12937.2 KFY01316.1 - 0.06 13.0 0.6 0.21 11.3 0.0 2.2 3 0 0 3 3 3 0 F-box-like Hydant_A_N PF05378.8 KFY01316.1 - 0.12 11.8 0.0 0.97 8.9 0.0 2.1 1 1 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region Arginase PF00491.16 KFY01318.1 - 2.2e-43 148.5 0.1 2.6e-43 148.3 0.1 1.0 1 0 0 1 1 1 1 Arginase family Fungal_trans_2 PF11951.3 KFY01319.1 - 9.3e-30 103.4 1.7 1.1e-29 103.2 1.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acatn PF13000.2 KFY01320.1 - 1.1e-137 459.8 25.0 7.9e-79 265.6 6.4 3.2 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 MFS_1 PF07690.11 KFY01320.1 - 7.9e-27 93.8 61.6 2.4e-21 75.8 14.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF3723 PF12520.3 KFY01351.1 - 1.4e-35 122.8 0.0 1.7e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) DUF1943 PF09172.6 KFY01351.1 - 0.045 12.6 0.2 0.074 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DUF3723 PF12520.3 KFY01352.1 - 1.4e-13 50.2 0.4 8.5e-13 47.6 0.2 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) p450 PF00067.17 KFY01354.1 - 6e-23 81.0 0.0 4.7e-22 78.1 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Lactamase_B_3 PF13483.1 KFY01355.1 - 7.4e-06 25.7 0.0 1.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 KFY01355.1 - 0.0013 18.3 0.2 0.0017 17.9 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF3723 PF12520.3 KFY01356.1 - 1.4e-83 281.1 2.0 6.4e-83 278.9 1.4 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3723) Cutinase PF01083.17 KFY01357.1 - 0.062 13.0 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Cutinase Y_phosphatase3C PF13348.1 KFY01357.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family C-terminal region DUF2029 PF09594.5 KFY01358.1 - 0.007 15.8 2.5 0.007 15.8 1.7 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2029) DUF3593 PF12159.3 KFY01358.1 - 0.024 14.4 2.4 0.3 10.9 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3593) EcsB PF05975.7 KFY01358.1 - 0.081 11.3 0.1 0.081 11.3 0.0 2.3 2 1 0 3 3 3 0 Bacterial ABC transporter protein EcsB DUF4442 PF14539.1 KFY01358.1 - 0.095 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) DUF4064 PF13273.1 KFY01358.1 - 0.11 12.5 3.4 0.47 10.5 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) COX15-CtaA PF02628.10 KFY01358.1 - 0.2 10.4 4.6 0.25 10.1 2.3 1.7 1 1 1 2 2 2 0 Cytochrome oxidase assembly protein OST3_OST6 PF04756.8 KFY01358.1 - 0.26 10.8 3.2 10 5.6 0.0 2.3 2 1 0 2 2 2 0 OST3 / OST6 family DUF21 PF01595.15 KFY01358.1 - 3.3 6.9 8.9 1.2 8.4 2.4 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF21 MAT1 PF06391.8 KFY01361.1 - 0.066 12.7 4.7 0.094 12.2 3.2 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 DUF2072 PF09845.4 KFY01361.1 - 0.11 12.4 4.4 0.18 11.7 3.0 1.5 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) DDHD PF02862.12 KFY01361.1 - 0.35 10.6 3.6 0.47 10.1 2.5 1.1 1 0 0 1 1 1 0 DDHD domain Trypan_PARP PF05887.6 KFY01363.1 - 0.17 11.7 7.4 0.26 11.1 5.2 1.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Condensation PF00668.15 KFY01366.1 - 1.2e-29 103.1 0.0 1.8e-16 59.9 0.0 2.1 1 1 1 2 2 2 2 Condensation domain PP-binding PF00550.20 KFY01366.1 - 6.3e-09 35.9 0.1 1.6e-08 34.6 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site RNA_pol PF00940.14 KFY01367.1 - 3.1e-166 552.8 0.1 4.8e-166 552.2 0.1 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 KFY01367.1 - 5.7e-80 268.9 3.4 1.3e-79 267.7 2.3 1.7 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Oligomerisation PF02410.10 KFY01368.1 - 5.9e-07 29.4 0.1 0.015 15.3 0.1 2.7 3 0 0 3 3 3 2 Oligomerisation domain Tim54 PF11711.3 KFY01368.1 - 0.76 8.3 2.9 1.5 7.3 2.0 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Acetyltransf_1 PF00583.19 KFY01369.1 - 5.4e-20 71.2 0.0 7.3e-20 70.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFY01369.1 - 1.3e-11 44.6 0.0 1.6e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFY01369.1 - 4.7e-10 39.4 0.0 6.7e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFY01369.1 - 1e-06 28.8 0.0 1.3e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KFY01369.1 - 1.1e-06 28.6 0.0 1.4e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFY01369.1 - 1.1e-06 28.2 0.0 1.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 KFY01369.1 - 4.2e-06 26.9 0.0 4.7e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFY01369.1 - 4.9e-05 23.1 0.0 7.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 KFY01369.1 - 0.073 12.9 0.0 0.18 11.6 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3636 PF12331.3 KFY01370.1 - 1e-42 145.2 0.0 2.3e-42 144.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) CTP_transf_1 PF01148.15 KFY01371.1 - 2.3e-82 276.5 29.8 2.8e-82 276.2 20.6 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Thiolase_N PF00108.18 KFY01372.1 - 1.1e-73 247.4 0.9 1.8e-73 246.7 0.6 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFY01372.1 - 4e-40 136.0 0.2 9.1e-40 134.9 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KFY01372.1 - 0.0007 19.2 0.8 0.08 12.6 0.2 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 KFY01372.1 - 0.0084 16.0 0.0 0.026 14.5 0.0 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Sulfate_transp PF00916.15 KFY01373.1 - 4.2e-55 186.7 0.1 9.2e-55 185.6 0.1 1.6 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KFY01373.1 - 2e-29 101.0 5.1 6.7e-29 99.3 3.5 2.0 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KFY01373.1 - 9.6e-15 54.0 0.0 1.8e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KFY01373.1 - 0.014 15.3 0.0 0.04 13.9 0.0 1.8 1 1 0 1 1 1 0 STAS domain Keratin_assoc PF09775.4 KFY01373.1 - 0.75 9.3 6.0 0.081 12.4 0.4 2.0 2 0 0 2 2 2 0 Keratinocyte-associated protein 2 Adaptin_N PF01602.15 KFY01374.1 - 3.7e-137 457.8 7.8 4.6e-137 457.5 5.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KFY01374.1 - 8.5e-17 61.5 3.0 1.3e-16 60.9 0.0 2.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KFY01374.1 - 1.3e-16 60.6 3.2 4.4e-10 39.6 0.0 4.5 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 KFY01374.1 - 1.5e-12 46.4 1.4 0.00012 21.8 0.0 5.1 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 KFY01374.1 - 3.1e-06 27.4 5.7 0.45 11.0 0.0 6.2 4 2 2 6 6 6 2 HEAT-like repeat Arm PF00514.18 KFY01374.1 - 1.5e-05 24.6 0.1 3.7 7.5 0.0 4.7 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 KFY01374.1 - 0.00012 21.6 0.2 0.34 10.6 0.0 4.5 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.3 KFY01374.1 - 0.00093 18.6 2.1 1.2 8.4 0.1 3.3 3 0 0 3 3 3 2 CLASP N terminal T_hemolysin PF12261.3 KFY01374.1 - 0.12 11.9 0.1 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Thermostable hemolysin DUF1077 PF06417.7 KFY01375.1 - 1.9e-51 172.6 0.8 2.3e-51 172.3 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) ADH_zinc_N PF00107.21 KFY01376.1 - 2e-22 79.1 0.3 3e-22 78.5 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFY01376.1 - 3.4e-08 34.4 0.3 8e-08 33.2 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFY01376.1 - 0.017 14.8 0.0 0.041 13.6 0.0 1.7 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 KFY01376.1 - 0.061 12.8 1.3 0.095 12.2 0.3 1.6 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase UL11 PF11094.3 KFY01376.1 - 0.065 13.0 0.1 5.4 6.9 0.0 2.6 2 0 0 2 2 2 0 Membrane-associated tegument protein GYF PF02213.11 KFY01377.1 - 8.5e-17 60.4 0.1 1.7e-16 59.4 0.1 1.6 1 0 0 1 1 1 1 GYF domain Rick_17kDa_Anti PF05433.10 KFY01379.1 - 0.0022 17.6 18.5 0.0022 17.6 12.9 2.1 2 0 0 2 2 2 1 Glycine zipper 2TM domain SR-25 PF10500.4 KFY01379.1 - 0.097 12.1 8.3 0.12 11.7 5.7 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.6 KFY01379.1 - 0.53 10.3 11.2 0.74 9.8 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Gly-zipper_OmpA PF13436.1 KFY01379.1 - 2.3 7.9 9.1 5.5 6.6 6.3 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain BLVR PF06375.6 KFY01379.1 - 4.8 6.9 10.6 6.5 6.5 7.4 1.1 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) HlyIII PF03006.15 KFY01380.1 - 6.6e-60 202.2 19.0 7.9e-60 202.0 13.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4231 PF14015.1 KFY01380.1 - 0.41 10.6 2.7 0.96 9.4 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) NADH-u_ox-rdase PF10785.4 KFY01380.1 - 3.4 7.9 10.1 2.9 8.1 1.3 3.2 4 1 1 5 5 5 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit zf-C2HC5 PF06221.8 KFY01381.1 - 2.5e-21 75.1 4.0 4e-21 74.5 2.8 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type PAT1 PF09770.4 KFY01381.1 - 0.34 9.0 7.3 0.47 8.6 5.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Aminotran_5 PF00266.14 KFY01382.1 - 5.9e-21 74.6 0.0 7.4e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KFY01382.1 - 0.00044 19.2 0.0 0.00066 18.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II SIS PF01380.17 KFY01384.1 - 1.4e-51 173.5 0.0 5.1e-28 97.3 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 KFY01384.1 - 6.7e-27 94.1 0.0 4.3e-18 65.1 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KFY01384.1 - 1.7e-19 70.0 0.0 3.7e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KFY01384.1 - 1.7e-12 47.1 0.0 3.7e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KFY01384.1 - 7.4e-07 28.1 0.0 1.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II AAA PF00004.24 KFY01385.1 - 2.1e-42 144.4 0.0 3.5e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFY01385.1 - 6.4e-07 29.5 0.1 5.8e-05 23.1 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 KFY01385.1 - 3.2e-06 26.9 0.2 8.5e-05 22.3 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFY01385.1 - 6e-06 26.4 0.1 0.0022 18.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 KFY01385.1 - 7.1e-06 26.0 0.0 2.2e-05 24.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 KFY01385.1 - 1.2e-05 24.4 0.0 2.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KFY01385.1 - 0.00043 19.9 0.1 0.00097 18.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 KFY01385.1 - 0.00075 18.5 0.0 0.0018 17.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 KFY01385.1 - 0.0027 17.5 0.0 0.011 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFY01385.1 - 0.0028 18.4 1.8 0.0057 17.4 0.5 2.3 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 KFY01385.1 - 0.0034 17.2 0.0 0.0071 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFY01385.1 - 0.0037 17.5 0.2 0.018 15.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KFY01385.1 - 0.0039 16.6 0.1 0.0079 15.6 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KFY01385.1 - 0.0045 15.7 0.0 0.0081 14.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 KFY01385.1 - 0.0051 16.0 0.0 0.0096 15.0 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KFY01385.1 - 0.01 15.9 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.21 KFY01385.1 - 0.013 14.9 0.0 0.051 13.0 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 KFY01385.1 - 0.016 14.6 0.2 0.081 12.3 0.1 2.0 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KFY01385.1 - 0.019 14.0 0.0 0.041 12.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin UPF0079 PF02367.12 KFY01385.1 - 0.019 14.5 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 KFY01385.1 - 0.024 14.2 0.1 0.052 13.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KFY01385.1 - 0.029 13.9 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KFY01385.1 - 0.032 14.1 0.0 0.078 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KFY01385.1 - 0.038 13.1 0.1 0.13 11.3 0.0 1.9 2 0 0 2 2 2 0 KaiC NACHT PF05729.7 KFY01385.1 - 0.041 13.5 0.1 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain ResIII PF04851.10 KFY01385.1 - 0.053 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 KFY01385.1 - 0.054 13.1 0.0 0.25 11.0 0.0 2.0 1 1 0 1 1 1 0 Archaeal ATPase PhoH PF02562.11 KFY01385.1 - 0.057 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.1 KFY01385.1 - 0.064 12.8 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KFY01385.1 - 0.084 12.9 0.0 0.21 11.6 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KFY01385.1 - 0.085 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 KFY01385.1 - 0.63 10.3 3.4 3.1 8.0 0.1 2.6 2 1 0 2 2 2 0 AAA domain Enolase_C PF00113.17 KFY01386.1 - 1.3e-150 500.3 0.0 1.8e-150 499.9 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KFY01386.1 - 3.2e-58 195.3 0.1 5e-58 194.7 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE PF01188.16 KFY01386.1 - 0.0081 16.6 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_C PF13378.1 KFY01386.1 - 0.09 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Enolase C-terminal domain-like Glyco_hydro_61 PF03443.9 KFY01390.1 - 1.2e-57 195.2 0.4 1.8e-57 194.6 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 KFY01390.1 - 0.013 15.5 0.1 0.093 12.7 0.0 2.3 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Glyco_hydro_61 PF03443.9 KFY01391.1 - 3.9e-49 167.4 0.0 4.7e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 KFY01391.1 - 0.078 13.0 0.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Lipase_GDSL PF00657.17 KFY01393.1 - 1.8e-09 37.7 2.1 3.6e-09 36.7 1.5 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KFY01393.1 - 1.9e-07 31.3 4.3 5.7e-07 29.8 3.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF1295 PF06966.7 KFY01394.1 - 1.2e-13 50.8 0.0 1.9e-13 50.2 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 KFY01394.1 - 3.7e-05 22.4 1.0 6e-05 21.7 0.7 1.5 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Sugar_tr PF00083.19 KFY01395.1 - 3.2e-106 355.6 20.9 3.6e-106 355.4 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY01395.1 - 1.3e-21 76.7 43.6 5.1e-20 71.4 14.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Hexokinase_1 PF00349.16 KFY01396.1 - 7.7e-29 100.4 0.0 1.1e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 KFY01396.1 - 6e-24 84.5 0.0 3e-16 59.3 0.0 3.0 1 1 1 2 2 2 2 Hexokinase Glucosamine_iso PF01182.15 KFY01397.1 - 6.9e-25 87.9 0.0 1.1e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase ABC2_membrane PF01061.19 KFY01398.1 - 2.9e-84 281.4 60.1 3.6e-46 156.9 13.7 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KFY01398.1 - 2.3e-35 121.8 0.0 8.6e-18 64.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KFY01398.1 - 5.5e-28 96.6 5.2 6.5e-24 83.5 0.0 3.6 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 KFY01398.1 - 7.4e-11 41.6 34.6 4e-07 29.3 10.5 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 KFY01398.1 - 5.7e-07 29.5 0.1 1.8e-06 27.9 0.0 1.9 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 KFY01398.1 - 1.7e-06 27.9 0.1 0.0015 18.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KFY01398.1 - 2.9e-06 26.8 0.4 0.0051 16.2 0.0 3.1 4 0 0 4 4 2 2 AAA domain AAA_17 PF13207.1 KFY01398.1 - 4.9e-06 27.3 0.0 0.005 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KFY01398.1 - 3.3e-05 24.0 0.1 0.1 12.5 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KFY01398.1 - 6.7e-05 22.3 0.5 0.0067 15.9 0.2 3.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KFY01398.1 - 0.00026 21.1 0.0 0.13 12.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain cobW PF02492.14 KFY01398.1 - 0.00043 19.7 0.8 0.013 14.9 0.3 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 KFY01398.1 - 0.00045 20.2 0.2 0.015 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KFY01398.1 - 0.00071 18.8 0.0 0.0024 17.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 KFY01398.1 - 0.002 17.8 0.5 0.8 9.5 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain UPF0079 PF02367.12 KFY01398.1 - 0.0028 17.2 0.7 1.2 8.7 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 KFY01398.1 - 0.0032 17.7 0.0 0.21 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KFY01398.1 - 0.0049 16.8 0.1 0.034 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 KFY01398.1 - 0.0059 15.8 0.0 0.74 8.9 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.4 KFY01398.1 - 0.0062 16.0 0.1 2.4 7.6 0.1 3.2 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 KFY01398.1 - 0.011 15.3 0.4 3.4 7.3 0.1 2.4 2 0 0 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 KFY01398.1 - 0.028 14.1 0.0 2.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 KFY01398.1 - 0.043 13.2 0.2 5 6.5 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 KFY01398.1 - 0.092 12.9 0.3 17 5.6 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KFY01398.1 - 0.11 11.8 0.4 7.3 5.9 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain Miro PF08477.8 KFY01398.1 - 0.2 12.1 0.0 8.4 6.9 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 KFY01398.1 - 0.31 11.3 0.1 0.7 10.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 KFY01398.1 - 0.72 8.8 0.0 4 6.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain CENP-Q PF13094.1 KFY01414.1 - 9.5e-35 119.9 6.1 9.5e-35 119.9 4.2 2.8 3 1 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit Totivirus_coat PF05518.6 KFY01414.1 - 7.3 4.2 13.1 13 3.4 9.1 1.3 1 0 0 1 1 1 0 Totivirus coat protein Zn_clus PF00172.13 KFY01415.1 - 4e-06 26.6 8.5 7.8e-06 25.7 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPO22 PF08631.5 KFY01416.1 - 1.3e-41 142.5 8.5 7.6e-24 84.2 0.8 3.2 3 1 1 4 4 4 2 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.1 KFY01416.1 - 4.6e-08 33.2 0.1 0.0051 17.1 0.0 4.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFY01416.1 - 1.1e-06 28.4 4.2 0.04 13.8 0.0 4.7 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFY01416.1 - 0.0023 17.5 4.7 0.34 10.6 0.1 4.6 3 1 1 4 4 4 1 TPR repeat TPR_2 PF07719.12 KFY01416.1 - 1.2 9.2 13.0 0.92 9.5 0.0 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat Ank_2 PF12796.2 KFY01417.1 - 1e-34 118.6 0.1 5.1e-09 36.3 0.0 5.4 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFY01417.1 - 5e-34 114.4 10.7 8.5e-07 28.4 0.0 9.4 10 0 0 10 10 10 7 Ankyrin repeat Ank_4 PF13637.1 KFY01417.1 - 4.4e-31 106.6 2.2 9.8e-10 38.6 0.0 7.3 5 2 3 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY01417.1 - 1.1e-23 80.8 7.7 9e-06 25.4 0.0 8.7 9 1 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.1 KFY01417.1 - 1.3e-23 82.4 1.6 6.9e-08 32.4 0.2 5.6 4 1 1 5 5 5 5 Ankyrin repeats (many copies) YuzL PF14115.1 KFY01417.1 - 0.086 13.1 0.3 0.21 11.9 0.0 1.7 2 0 0 2 2 2 0 YuzL-like protein CtaG_Cox11 PF04442.9 KFY01419.1 - 7.6e-57 191.3 0.0 1.4e-56 190.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 C2 PF00168.25 KFY01419.1 - 5.1e-21 74.3 0.0 6.8e-16 57.8 0.0 2.6 2 0 0 2 2 2 2 C2 domain Sec6 PF06046.8 KFY01420.1 - 6.5e-161 536.2 3.8 1.1e-160 535.5 2.6 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.7 KFY01420.1 - 0.028 13.2 12.3 0.21 10.3 2.8 2.8 1 1 2 3 3 3 0 Vps53-like, N-terminal DASH_Duo1 PF08651.5 KFY01420.1 - 0.059 12.9 3.4 0.1 12.1 0.3 3.1 3 1 1 4 4 4 0 DASH complex subunit Duo1 Ribosomal_L30 PF00327.15 KFY01421.1 - 7.4e-15 54.2 0.3 1.2e-14 53.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e NUC173 PF08161.7 KFY01422.1 - 9.7e-77 256.8 0.6 1.7e-74 249.5 0.0 3.2 3 0 0 3 3 3 2 NUC173 domain Vac14_Fab1_bd PF12755.2 KFY01422.1 - 0.11 12.8 0.9 6.5 7.2 0.0 3.9 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region DUF2508 PF10704.4 KFY01422.1 - 0.25 11.5 4.9 0.62 10.2 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) RNA_pol_Rpb1_7 PF04990.7 KFY01422.1 - 3.1 7.5 8.4 1 9.0 0.9 3.0 3 0 0 3 3 3 0 RNA polymerase Rpb1, domain 7 CorA PF01544.13 KFY01433.1 - 0.0018 17.3 0.0 0.0037 16.3 0.0 1.5 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DIOX_N PF14226.1 KFY01434.1 - 5.2e-23 81.7 0.0 9.5e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KFY01434.1 - 3e-07 30.6 0.0 5.8e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AATase PF07247.7 KFY01435.1 - 6e-14 51.4 0.0 3.6e-09 35.7 0.0 2.9 2 1 0 2 2 2 2 Alcohol acetyltransferase Condensation PF00668.15 KFY01435.1 - 0.016 14.0 0.1 0.19 10.5 0.0 2.5 2 1 0 2 2 2 0 Condensation domain GNVR PF13807.1 KFY01435.1 - 0.036 13.8 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase PAH PF02671.16 KFY01436.1 - 1.1e-06 28.1 0.0 2.2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Paired amphipathic helix repeat AfsA PF03756.8 KFY01438.1 - 0.12 12.1 0.3 7.5 6.2 0.1 2.4 2 0 0 2 2 2 0 A-factor biosynthesis hotdog domain F-box-like PF12937.2 KFY01453.1 - 0.00038 20.1 0.0 0.00093 18.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFY01453.1 - 0.0011 18.5 0.0 0.0026 17.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain Methyltransf_23 PF13489.1 KFY01454.1 - 4.4e-16 59.0 0.0 8.3e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY01454.1 - 5.1e-06 27.0 0.0 6.3e-05 23.5 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY01454.1 - 2.2e-05 24.0 0.0 0.00024 20.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY01454.1 - 2.3e-05 24.7 0.0 0.00011 22.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFY01454.1 - 0.0044 16.1 0.0 0.017 14.2 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KFY01454.1 - 0.021 15.2 0.0 0.082 13.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.14 KFY01454.1 - 0.032 14.2 0.0 0.048 13.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 KFY01454.1 - 0.051 13.9 0.0 0.32 11.3 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 KFY01454.1 - 0.064 13.2 0.0 0.24 11.4 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Glyco_tran_28_C PF04101.11 KFY01455.1 - 5.5e-14 52.1 0.0 1.9e-12 47.1 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KFY01455.1 - 0.0081 15.3 0.0 0.011 14.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 MRP-S28 PF10213.4 KFY01456.1 - 2.3e-44 150.5 0.1 4.9e-44 149.4 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein FMN_red PF03358.10 KFY01458.1 - 4.2e-31 107.5 0.0 5.6e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KFY01458.1 - 3.7e-10 39.6 0.0 6.8e-10 38.7 0.0 1.5 2 0 0 2 2 2 1 Flavodoxin-like fold Lyase_1 PF00206.15 KFY01459.1 - 1.4e-85 287.2 0.0 1.9e-85 286.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 KFY01459.1 - 1.9e-24 85.5 0.2 3.8e-24 84.5 0.1 1.5 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Aldedh PF00171.17 KFY01460.1 - 1e-76 258.1 0.0 1.2e-76 257.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Yippee-Mis18 PF03226.9 KFY01462.1 - 1.5e-21 76.2 0.0 2.7e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 KFY01462.1 - 0.086 12.7 0.2 1 9.2 0.1 2.1 2 0 0 2 2 2 0 C-terminal domain of RIG-I ODC_AZ PF02100.12 KFY01463.1 - 6.3e-28 96.4 0.0 1e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Phage_int_SAM_1 PF02899.12 KFY01464.1 - 0.16 12.1 0.7 0.76 9.9 0.1 2.3 2 1 1 3 3 3 0 Phage integrase, N-terminal SAM-like domain WTX PF09422.5 KFY01465.1 - 0.0016 17.5 2.1 0.0016 17.5 1.5 1.4 2 0 0 2 2 2 1 WTX protein TFIIIC_sub6 PF10419.4 KFY01466.1 - 1.3e-12 46.9 0.0 9.8e-12 44.1 0.0 2.3 2 0 0 2 2 2 1 TFIIIC subunit FA_desaturase PF00487.19 KFY01467.1 - 1.2e-15 57.6 15.4 2.3e-15 56.7 10.6 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Aldedh PF00171.17 KFY01476.1 - 0.0041 15.5 1.4 0.0048 15.2 1.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TctA PF01970.11 KFY01476.1 - 0.13 10.6 0.1 0.14 10.5 0.1 1.0 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family YjbE PF11106.3 KFY01476.1 - 4.4 7.3 7.5 0.76 9.7 2.1 2.0 1 1 1 2 2 2 0 Exopolysaccharide production protein YjbE PCI PF01399.22 KFY01477.1 - 0.00064 20.0 0.0 0.0018 18.5 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.1 KFY01477.1 - 0.0017 17.9 0.0 0.32 10.8 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFY01477.1 - 0.067 13.8 1.9 1.2 9.8 0.3 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Rep_fac-A_C PF08646.5 KFY01478.1 - 7.2e-57 191.1 2.7 7.3e-55 184.6 0.5 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 KFY01478.1 - 3.6e-22 78.0 0.0 7.8e-22 76.9 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 KFY01478.1 - 4.3e-17 61.7 0.1 1.9e-11 43.6 0.0 4.3 4 1 1 5 5 5 2 OB-fold nucleic acid binding domain DUF223 PF02721.9 KFY01478.1 - 0.0044 17.0 0.1 0.011 15.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF223 PALP PF00291.20 KFY01479.1 - 6.5e-69 232.4 0.8 3.4e-51 174.3 0.2 2.1 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme IlvN PF07991.7 KFY01480.1 - 5.5e-45 152.6 0.1 8.4e-45 152.0 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 KFY01480.1 - 2e-44 151.0 0.0 2.9e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain UQ_con PF00179.21 KFY01481.1 - 1.4e-38 131.4 0.0 1.8e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFY01481.1 - 0.044 13.5 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Acyl-thio_N PF12590.3 KFY01481.1 - 0.056 13.9 0.2 0.085 13.3 0.1 1.2 1 0 0 1 1 1 0 Acyl-ATP thioesterase UEV PF05743.8 KFY01481.1 - 0.14 11.8 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain Chitin_synth_1 PF01644.12 KFY01482.1 - 3.9e-69 231.6 0.1 5.9e-69 231.0 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KFY01482.1 - 1.1e-28 98.6 0.1 2.9e-28 97.3 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KFY01482.1 - 5.7e-24 84.3 0.5 3.2e-19 68.7 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KFY01482.1 - 6.2e-11 42.3 0.0 6.2e-11 42.3 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KFY01482.1 - 9.9e-08 32.0 0.0 2e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF3987 PF13148.1 KFY01482.1 - 0.37 9.3 0.4 0.56 8.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) FRG2 PF15315.1 KFY01489.1 - 0.034 14.1 0.1 0.052 13.5 0.1 1.3 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Ank_2 PF12796.2 KFY01490.1 - 3.7e-91 299.6 18.8 2.5e-22 78.9 0.2 4.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFY01490.1 - 1.7e-61 201.1 19.7 3.1e-08 33.0 0.0 9.7 10 0 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 KFY01490.1 - 1.5e-50 168.7 18.1 1.9e-10 40.9 0.3 6.1 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY01490.1 - 3.9e-46 150.4 11.8 9.4e-06 25.3 0.0 9.5 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 KFY01490.1 - 2.4e-35 119.7 17.8 6.9e-06 26.1 0.8 8.5 1 1 8 9 9 9 7 Ankyrin repeats (many copies) gag-asp_proteas PF13975.1 KFY01490.1 - 0.036 13.8 1.1 11 5.9 0.0 3.7 4 0 0 4 4 4 0 gag-polyprotein putative aspartyl protease SpoU_sub_bind PF08032.7 KFY01490.1 - 0.05 13.7 0.1 70 3.6 0.0 4.7 7 0 0 7 7 7 0 RNA 2'-O ribose methyltransferase substrate binding Bactofilin PF04519.8 KFY01490.1 - 0.061 13.3 0.8 38 4.3 0.0 3.8 3 1 0 3 3 3 0 Polymer-forming cytoskeletal DUF1691 PF07950.6 KFY01491.1 - 0.0025 17.7 0.1 0.004 17.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1691) KfrA_N PF11740.3 KFY01492.1 - 0.28 11.6 7.3 0.21 12.0 1.6 2.6 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF972 PF06156.8 KFY01492.1 - 0.62 10.4 3.4 0.33 11.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Nipped-B_C PF12830.2 KFY01493.1 - 2.9e-33 115.0 4.6 2.8e-32 111.8 0.6 2.9 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus HEAT_2 PF13646.1 KFY01493.1 - 0.00023 21.3 1.4 0.0028 17.8 0.3 3.3 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.17 KFY01493.1 - 0.00025 20.8 4.0 1.4 9.2 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat Cohesin_HEAT PF12765.2 KFY01493.1 - 0.007 16.3 8.6 0.059 13.3 0.2 4.0 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.1 KFY01493.1 - 0.017 15.6 0.1 0.43 11.1 0.0 3.3 2 0 0 2 2 2 0 HEAT-like repeat Bd3614-deam PF14439.1 KFY01494.1 - 3.6 7.4 6.1 4.8 7.0 4.3 1.5 1 1 0 1 1 1 0 Bd3614-like deaminase COPI_C PF06957.6 KFY01494.1 - 6.5 5.1 13.5 7 5.0 9.3 1.0 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Methyltransf_32 PF13679.1 KFY01496.1 - 6.9e-18 64.6 3.4 6.5e-17 61.5 2.3 2.2 1 1 0 1 1 1 1 Methyltransferase domain Syntaxin-6_N PF09177.6 KFY01497.1 - 1.8e-24 85.9 1.5 1.7e-23 82.8 0.0 2.3 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 KFY01497.1 - 3.3e-12 45.8 2.6 3.3e-12 45.8 1.8 3.2 3 0 0 3 3 3 1 SNARE domain DUF869 PF05911.6 KFY01497.1 - 0.0019 16.5 1.3 0.0023 16.2 0.9 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Herpes_UL6 PF01763.11 KFY01497.1 - 0.046 11.8 2.1 0.061 11.4 1.4 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like CENP-Q PF13094.1 KFY01497.1 - 0.17 11.9 9.4 0.57 10.1 6.3 1.8 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Myosin_tail_1 PF01576.14 KFY01497.1 - 0.18 9.5 10.4 0.83 7.2 4.5 2.0 1 1 1 2 2 2 0 Myosin tail Rifin_STEVOR PF02009.11 KFY01497.1 - 0.21 11.1 0.6 0.44 10.1 0.4 1.6 1 1 0 1 1 1 0 Rifin/stevor family DUF1664 PF07889.7 KFY01497.1 - 0.3 10.8 3.5 0.95 9.2 0.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF812 PF05667.6 KFY01497.1 - 0.68 8.3 7.2 2.4 6.5 5.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Mnd1 PF03962.10 KFY01497.1 - 0.68 9.5 5.4 2.1 7.9 3.7 1.8 1 1 0 1 1 1 0 Mnd1 family APG6 PF04111.7 KFY01497.1 - 1.7 7.6 7.7 0.64 8.9 0.1 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 KFY01497.1 - 2.2 8.0 11.1 7.3 6.4 6.8 2.0 1 1 1 2 2 2 0 Tropomyosin like B56 PF01603.15 KFY01498.1 - 4.9e-172 572.1 6.1 6.1e-172 571.8 4.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Tau95 PF09734.4 KFY01499.1 - 2e-62 211.3 0.0 2.6e-62 210.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit NOA36 PF06524.7 KFY01499.1 - 0.42 9.8 8.3 0.64 9.2 5.8 1.2 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.3 KFY01499.1 - 0.67 9.8 17.6 2 8.2 12.2 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 NAP PF00956.13 KFY01500.1 - 4.4e-48 163.5 0.3 5.7e-48 163.1 0.2 1.1 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) PARG_cat PF05028.9 KFY01501.1 - 3.4e-36 125.1 0.0 6.7e-36 124.2 0.0 1.4 1 1 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Cnd3 PF12719.2 KFY01502.1 - 1.3e-95 319.8 0.8 1.3e-95 319.8 0.6 2.7 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 KFY01502.1 - 6e-10 39.2 10.1 4.2e-05 23.7 0.8 5.4 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.17 KFY01502.1 - 4.8e-07 29.3 9.0 0.05 13.6 0.0 7.5 8 0 0 8 8 8 1 HEAT repeat Cnd1 PF12717.2 KFY01502.1 - 0.017 15.0 1.2 0.75 9.6 0.2 4.2 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.9 KFY01502.1 - 0.074 12.1 3.8 3.6 6.6 0.1 2.9 3 0 0 3 3 3 0 V-ATPase subunit H HEAT_EZ PF13513.1 KFY01502.1 - 7.5 7.1 20.5 0.28 11.7 0.8 6.6 5 1 3 8 8 8 0 HEAT-like repeat PALP PF00291.20 KFY01503.1 - 4.1e-60 203.5 0.2 4.8e-60 203.3 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ribosomal_L19 PF01245.15 KFY01505.1 - 4.2e-19 68.4 0.1 7.1e-19 67.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 Pkinase PF00069.20 KFY01508.1 - 2.1e-70 236.8 0.0 3.6e-70 236.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY01508.1 - 2e-35 122.1 0.0 3.4e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFY01508.1 - 0.00017 20.7 0.0 0.00032 19.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFY01508.1 - 0.00051 19.0 0.1 0.0018 17.2 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Peptidase_C65 PF10275.4 KFY01536.1 - 3.7e-30 105.0 0.0 4.6e-17 62.1 0.0 2.2 1 1 1 2 2 2 2 Peptidase C65 Otubain SET PF00856.23 KFY01546.1 - 8.8e-13 48.8 0.2 9e-12 45.5 0.1 2.2 1 1 0 1 1 1 1 SET domain DUF3505 PF12013.3 KFY01547.1 - 0.0054 16.9 0.1 0.012 15.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) zf-H2C2_5 PF13909.1 KFY01547.1 - 0.038 14.2 0.2 0.072 13.3 0.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc-finger domain ADIP PF11559.3 KFY01554.1 - 0.014 15.2 3.1 0.022 14.6 2.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FlxA PF14282.1 KFY01554.1 - 0.025 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 FlxA-like protein DUF3138 PF11336.3 KFY01554.1 - 0.12 10.5 1.3 0.13 10.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) RRM_1 PF00076.17 KFY01555.1 - 5.6e-42 141.2 0.3 1.7e-18 65.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY01555.1 - 1.2e-34 118.0 0.1 8.7e-18 64.0 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 KFY01555.1 - 1e-28 99.4 0.1 2.7e-28 98.0 0.0 1.7 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 KFY01555.1 - 5.4e-23 80.6 0.0 5.5e-09 35.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFY01555.1 - 0.006 16.4 0.0 0.055 13.3 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif MIP-T3 PF10243.4 KFY01555.1 - 1.6 7.0 18.7 15 3.9 13.8 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Cyt-b5 PF00173.23 KFY01556.1 - 1.3e-18 66.5 0.4 4.8e-18 64.7 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Anth_synt_I_N PF04715.8 KFY01556.1 - 0.013 15.4 0.1 0.028 14.4 0.1 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region Flu_M1 PF00598.14 KFY01556.1 - 0.03 13.7 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) Het-C PF07217.6 KFY01557.1 - 2.9e-281 934.0 0.0 3.4e-281 933.8 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C RRM_1 PF00076.17 KFY01567.1 - 3e-53 177.3 0.0 4.2e-18 64.7 0.0 3.9 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY01567.1 - 1.7e-42 143.2 0.0 6.3e-14 51.7 0.0 3.7 3 1 1 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFY01567.1 - 1.2e-23 82.6 0.0 2.7e-06 27.1 0.0 3.7 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KFY01567.1 - 8.1e-06 25.6 0.0 0.81 9.5 0.0 3.4 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.3 KFY01567.1 - 9.7e-06 25.2 0.0 0.43 10.3 0.0 4.0 4 1 0 4 4 4 2 Limkain b1 ATP-grasp_2 PF08442.5 KFY01567.1 - 0.00039 19.8 0.0 0.024 14.0 0.0 2.9 3 0 0 3 3 3 1 ATP-grasp domain IATP PF04568.7 KFY01567.1 - 0.73 9.9 2.5 3.4 7.7 1.8 2.2 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP MIF4G PF02854.14 KFY01568.1 - 6.5e-21 74.7 0.5 1.2e-20 73.8 0.3 1.5 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 KFY01568.1 - 1.7e-19 69.6 0.1 4.3e-19 68.2 0.0 1.8 2 0 0 2 2 2 1 MA3 domain SRP14 PF02290.10 KFY01569.1 - 2.7e-25 88.1 0.0 2.7e-25 88.1 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle 14kD protein Vps36_ESCRT-II PF11605.3 KFY01569.1 - 0.051 13.3 0.0 0.52 10.1 0.0 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 Pyr_redox_dim PF02852.17 KFY01570.1 - 2.4e-40 136.9 1.0 4.9e-40 135.9 0.2 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 KFY01570.1 - 8.9e-37 126.9 22.1 1e-35 123.4 15.3 3.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFY01570.1 - 1e-22 80.3 13.4 1.3e-19 70.3 0.9 3.6 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KFY01570.1 - 3.4e-10 39.5 0.3 3.4e-10 39.5 0.2 2.7 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 KFY01570.1 - 8.3e-10 38.0 8.6 6.3e-09 35.1 1.4 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KFY01570.1 - 1e-09 38.2 5.0 5e-06 26.4 0.5 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFY01570.1 - 3.6e-08 32.6 11.9 8.9e-08 31.3 3.0 2.9 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.12 KFY01570.1 - 3.1e-07 29.7 3.9 1.4e-05 24.2 0.1 2.4 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 KFY01570.1 - 5.4e-07 28.8 19.6 7.3e-06 25.1 0.5 4.1 3 1 1 4 4 4 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KFY01570.1 - 9.8e-07 28.1 6.3 0.0064 15.5 0.2 2.5 2 1 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 KFY01570.1 - 2.9e-05 22.7 17.2 4.9e-05 21.9 1.6 4.0 4 0 0 4 4 4 1 HI0933-like protein Pyr_redox_3 PF13738.1 KFY01570.1 - 3.6e-05 23.9 5.6 0.011 15.8 1.8 3.0 1 1 2 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFY01570.1 - 9.5e-05 21.4 0.8 0.46 9.3 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 KFY01570.1 - 0.00034 20.2 3.4 0.15 11.6 0.2 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 KFY01570.1 - 0.0018 18.4 1.8 0.5 10.6 0.1 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.14 KFY01570.1 - 0.093 11.7 1.0 1.7 7.7 0.0 3.1 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FMO-like PF00743.14 KFY01570.1 - 0.18 9.9 0.7 0.29 9.2 0.5 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Lycopene_cycl PF05834.7 KFY01570.1 - 0.34 9.7 7.3 0.042 12.7 0.7 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 KFY01570.1 - 0.89 9.1 8.6 0.85 9.2 0.5 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 KFY01570.1 - 3.1 6.3 9.7 0.024 13.2 0.8 1.7 2 0 0 2 2 2 0 Tryptophan halogenase BHD_3 PF10405.4 KFY01584.1 - 7.8e-07 28.7 2.0 6.8 6.4 0.0 5.2 5 0 0 5 5 5 5 Rad4 beta-hairpin domain 3 Gamma-thionin PF00304.15 KFY01584.1 - 0.00028 20.8 44.9 0.27 11.2 2.2 5.5 5 0 0 5 5 5 4 Gamma-thionin family Ion_trans_2 PF07885.11 KFY01584.1 - 0.46 10.2 4.1 1.9e+02 1.8 0.0 4.7 5 0 0 5 5 5 0 Ion channel LCE PF14672.1 KFY01584.1 - 2.7 8.5 70.4 9.1 6.8 6.0 5.7 2 2 2 5 5 5 0 Late cornified envelope Methyltransf_18 PF12847.2 KFY01585.1 - 1.8e-10 41.3 0.4 4.1e-10 40.2 0.2 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY01585.1 - 2.3e-10 40.2 0.0 2.9e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY01585.1 - 8.6e-08 32.4 0.0 1.5e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFY01585.1 - 2.6e-07 30.4 0.0 4.6e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KFY01585.1 - 2.3e-06 26.9 0.0 3.6e-06 26.2 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 KFY01585.1 - 1.8e-05 25.1 0.0 3.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFY01585.1 - 4e-05 23.0 0.1 7.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 KFY01585.1 - 0.00031 21.1 0.0 0.00049 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFY01585.1 - 0.0008 19.4 0.1 0.0016 18.4 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFY01585.1 - 0.00095 18.3 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 KFY01585.1 - 0.0049 16.2 0.1 0.012 15.0 0.1 1.6 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 KFY01585.1 - 0.02 14.5 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 KFY01585.1 - 0.085 12.0 0.1 7.4 5.6 0.0 2.2 2 0 0 2 2 2 0 O-methyltransferase DUF3863 PF12979.2 KFY01585.1 - 0.087 11.4 0.1 7.5 5.0 0.0 2.3 1 1 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3863) DUF3446 PF11928.3 KFY01588.1 - 8.6 6.6 11.9 1.6 8.9 4.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3446) GMC_oxred_N PF00732.14 KFY01589.1 - 3.1e-50 170.9 0.1 4e-50 170.6 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFY01589.1 - 3.9e-39 134.2 0.1 6.6e-39 133.4 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KFY01589.1 - 1.2e-07 30.9 0.2 0.0029 16.5 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KFY01589.1 - 1.3e-05 24.3 0.0 0.0003 19.8 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KFY01589.1 - 7.8e-05 22.8 0.1 0.24 11.4 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFY01589.1 - 9.3e-05 22.2 0.2 0.1 12.4 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KFY01589.1 - 0.00093 19.1 0.0 0.0022 17.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KFY01589.1 - 0.0037 16.1 0.3 0.53 9.0 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KFY01589.1 - 0.01 14.7 0.1 0.019 13.8 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 KFY01589.1 - 0.029 14.2 0.4 0.13 12.0 0.1 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KFY01589.1 - 0.042 12.4 0.1 0.064 11.8 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.9 KFY01589.1 - 0.14 10.6 0.3 0.28 9.5 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Amidohydro_2 PF04909.9 KFY01591.1 - 4.9e-47 160.7 0.3 6e-47 160.4 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase UBN2 PF14223.1 KFY01591.1 - 0.11 12.2 0.0 0.55 10.0 0.0 2.0 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KFY01591.1 - 0.18 11.3 0.1 0.29 10.6 0.1 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type COesterase PF00135.23 KFY01592.1 - 1e-85 288.5 0.1 1.4e-85 288.0 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFY01592.1 - 0.013 15.1 0.0 0.045 13.3 0.0 1.8 1 1 0 1 1 1 0 alpha/beta hydrolase fold Sugar_tr PF00083.19 KFY01594.1 - 4.5e-82 276.0 17.6 5.3e-82 275.7 12.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY01594.1 - 2.5e-16 59.3 24.7 3.6e-12 45.6 15.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFY01594.1 - 1.5e-06 26.9 22.3 0.0029 16.0 0.2 2.8 2 1 1 3 3 3 3 MFS/sugar transport protein Peptidase_M56 PF05569.6 KFY01594.1 - 0.12 11.2 1.2 0.26 10.2 0.8 1.5 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF3671 PF12420.3 KFY01594.1 - 1.7 8.6 7.7 5.3 7.0 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function DUF4131 PF13567.1 KFY01594.1 - 6.3 6.1 12.8 0.3 10.4 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Alpha-amylase PF00128.19 KFY01595.1 - 5.9e-96 321.5 2.2 8.2e-96 321.0 1.5 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KFY01595.1 - 0.02 13.8 0.0 0.036 12.9 0.0 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme DUF3459 PF11941.3 KFY01595.1 - 0.12 12.4 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Amidase PF01425.16 KFY01596.1 - 0.00017 20.6 0.0 0.00018 20.5 0.0 1.0 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.11 KFY01597.1 - 4.1e-24 84.9 30.3 2e-22 79.3 23.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 KFY01598.1 - 7.2e-06 24.8 0.2 3.2e-05 22.7 0.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY01598.1 - 8.6e-05 22.3 11.3 0.00018 21.3 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.6 KFY01599.1 - 4e-05 23.7 0.0 6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Bac_luciferase PF00296.15 KFY01600.1 - 5.1e-57 193.3 1.0 9.7e-57 192.4 0.7 1.4 1 0 0 1 1 1 1 Luciferase-like monooxygenase UNC-93 PF05978.11 KFY01600.1 - 0.0017 17.9 2.6 0.0017 17.9 1.8 2.8 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 PC_rep PF01851.17 KFY01600.1 - 0.0058 16.8 0.0 26 5.2 0.1 4.8 6 0 0 6 6 6 1 Proteasome/cyclosome repeat MFS_1 PF07690.11 KFY01600.1 - 0.25 10.0 41.2 6.6 5.3 28.5 2.2 1 1 0 1 1 1 0 Major Facilitator Superfamily Pyr_redox_3 PF13738.1 KFY01601.1 - 5.4e-26 91.9 0.0 4e-25 89.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFY01601.1 - 1.3e-16 59.9 0.0 1.5e-15 56.4 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KFY01601.1 - 2.8e-09 36.8 0.0 1.8e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFY01601.1 - 5.4e-09 36.2 0.0 9.5e-08 32.1 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFY01601.1 - 1.4e-08 34.0 0.7 6.7e-08 31.8 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KFY01601.1 - 7.3e-05 22.5 0.7 0.047 13.4 0.1 4.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 KFY01601.1 - 0.00023 20.3 0.1 0.0011 18.1 0.0 2.0 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 KFY01601.1 - 0.00041 19.3 0.5 0.04 12.8 0.0 2.9 2 1 0 3 3 3 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 KFY01601.1 - 0.051 13.1 0.0 0.47 9.9 0.0 2.4 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain F-box PF00646.28 KFY01602.1 - 0.0002 20.9 0.6 0.00041 19.9 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFY01602.1 - 0.025 14.3 0.1 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 F-box-like VID27 PF08553.5 KFY01603.1 - 0 1129.9 0.1 0 1129.8 0.0 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Glyco_transf_20 PF00982.16 KFY01604.1 - 1.2e-195 650.5 0.0 1.4e-195 650.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Drc1-Sld2 PF11719.3 KFY01605.1 - 8.9e-84 282.0 15.8 1.1e-83 281.7 10.9 1.1 1 0 0 1 1 1 1 DNA replication and checkpoint protein HECT PF00632.20 KFY01606.1 - 1.5e-66 224.7 0.0 2.3e-66 224.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MFS_1 PF07690.11 KFY01606.1 - 9.5e-36 123.2 27.5 9.5e-36 123.2 19.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFY01606.1 - 0.00049 18.4 4.2 0.00081 17.7 2.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4576 PF15144.1 KFY01606.1 - 0.14 11.8 0.0 0.41 10.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) DUF3169 PF11368.3 KFY01606.1 - 8.8 5.4 7.4 4.2 6.4 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3169) 2Fe-2S_Ferredox PF11591.3 KFY01606.1 - 9.7 5.9 8.6 1 9.0 0.6 2.6 2 0 0 2 2 2 0 Ferredoxin chloroplastic transit peptide Asp PF00026.18 KFY01608.1 - 7.5e-72 242.2 9.3 8.9e-72 242.0 6.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFY01608.1 - 1.9e-08 34.4 0.2 1.9e-07 31.1 0.1 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KFY01608.1 - 3.1e-05 24.3 3.0 0.00028 21.3 0.7 2.9 2 1 0 2 2 2 1 Aspartyl protease Glyco_hydro_2_N PF02837.13 KFY01610.1 - 1.5e-08 34.4 0.0 2.8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KFY01610.1 - 2.9e-07 30.8 0.0 8e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 KFY01610.1 - 0.00012 21.0 0.0 0.00024 20.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Sugar_tr PF00083.19 KFY01611.1 - 6.7e-86 288.6 37.2 7.8e-86 288.4 25.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY01611.1 - 4.2e-33 114.5 34.4 4.2e-33 114.5 23.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFY01611.1 - 5.1e-05 21.8 6.8 5.1e-05 21.8 4.7 3.2 2 2 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 KFY01611.1 - 0.0004 18.7 3.6 0.0004 18.7 2.5 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) 7TM_GPCR_Srw PF10324.4 KFY01611.1 - 0.0029 16.7 1.4 0.0029 16.7 1.0 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF3413 PF11893.3 KFY01611.1 - 0.019 13.8 0.2 0.019 13.8 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3413) Fungal_trans PF04082.13 KFY01612.1 - 1.5e-11 43.6 1.2 2.3e-11 43.0 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KFY01612.1 - 0.00018 21.6 1.7 0.00043 20.4 1.2 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFY01612.1 - 0.00087 19.4 2.1 0.0037 17.4 1.4 2.2 1 0 0 1 1 1 1 C2H2-type zinc finger Meckelin PF09773.4 KFY01613.1 - 0.02 12.7 0.2 0.02 12.6 0.1 1.0 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) Herpes_gE PF02480.11 KFY01613.1 - 0.07 11.3 0.2 0.061 11.5 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PspB PF06667.7 KFY01613.1 - 0.11 12.4 0.4 0.22 11.4 0.1 1.7 2 0 0 2 2 2 0 Phage shock protein B PMP1_2 PF08114.6 KFY01613.1 - 0.15 11.6 3.4 0.25 10.8 2.3 1.4 1 0 0 1 1 1 0 ATPase proteolipid family SCIMP PF15050.1 KFY01613.1 - 0.32 10.8 2.6 0.51 10.2 1.8 1.3 1 0 0 1 1 1 0 SCIMP protein WD40 PF00400.27 KFY01614.1 - 8.7e-74 241.0 17.6 1.2e-11 44.0 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KFY01614.1 - 1e-06 27.2 8.3 0.0016 16.6 0.7 4.7 3 2 3 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFY01614.1 - 1.5e-05 23.9 0.3 0.1 11.3 0.1 2.8 1 1 0 2 2 2 2 Nup133 N terminal like Glyco_hydro_18 PF00704.23 KFY01615.1 - 2.8e-47 161.8 5.2 4.7e-47 161.1 3.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KFY01615.1 - 8.8e-08 31.9 0.3 0.02 14.7 0.0 2.5 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 KFY01615.1 - 0.006 16.5 3.4 0.006 16.5 2.4 3.5 3 0 0 3 3 3 1 Chitin recognition protein 2Fe-2S_thioredx PF01257.14 KFY01616.1 - 1.2e-59 200.0 0.1 1.7e-59 199.5 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin MARVEL PF01284.18 KFY01616.1 - 2.4e-17 63.1 10.2 3.4e-17 62.5 7.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF2976 PF11190.3 KFY01616.1 - 0.086 12.3 1.6 0.18 11.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) FAD_binding_3 PF01494.14 KFY01621.1 - 2e-25 89.6 0.0 1.4e-23 83.4 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain POLO_box PF00659.13 KFY01621.1 - 2e-07 30.8 0.2 0.00038 20.3 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region DAO PF01266.19 KFY01621.1 - 4.5e-07 29.1 0.8 1.9e-05 23.7 0.6 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KFY01621.1 - 3.3e-06 26.2 0.2 9.1e-05 21.5 0.0 2.7 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KFY01621.1 - 0.00026 20.9 0.0 0.00053 19.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KFY01621.1 - 0.00043 19.4 0.0 0.00099 18.2 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KFY01621.1 - 0.0019 17.3 0.0 0.021 13.9 0.0 2.1 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KFY01621.1 - 0.0036 15.8 0.2 0.0091 14.5 0.1 1.6 1 1 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 KFY01621.1 - 0.0038 15.9 0.0 0.064 11.8 0.0 2.6 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_9 PF13454.1 KFY01621.1 - 0.0066 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding SE PF08491.5 KFY01621.1 - 0.0079 15.0 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.1 KFY01621.1 - 0.024 14.6 0.1 0.072 13.1 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFY01621.1 - 0.056 12.2 0.4 0.092 11.5 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Asp_protease_2 PF13650.1 KFY01622.1 - 7.1e-07 29.6 0.0 1.2e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 KFY01622.1 - 0.00021 21.1 0.0 0.00035 20.4 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KFY01622.1 - 0.0043 16.8 0.0 0.0078 16.0 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KFY01623.1 - 1e-06 29.1 0.0 1.5e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KFY01623.1 - 0.005 16.6 0.0 0.0089 15.8 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 KFY01623.1 - 0.0055 16.6 0.0 0.011 15.6 0.0 1.6 1 1 0 1 1 1 1 Retroviral aspartyl protease Pkinase PF00069.20 KFY01624.1 - 9.7e-55 185.5 0.0 1.3e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY01624.1 - 3.5e-38 131.1 0.0 5.5e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KFY01624.1 - 0.0057 16.4 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KFY01624.1 - 0.0074 15.3 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFY01624.1 - 0.0079 15.1 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RRN3 PF05327.6 KFY01625.1 - 1.3e-176 588.0 0.0 1.3e-176 588.0 0.0 2.0 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Prefoldin_2 PF01920.15 KFY01626.1 - 1.9e-25 88.7 5.8 2.2e-25 88.4 4.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Mnd1 PF03962.10 KFY01626.1 - 0.0083 15.8 1.8 0.013 15.1 1.3 1.3 1 1 0 1 1 1 1 Mnd1 family DUF2205 PF10224.4 KFY01626.1 - 0.031 13.8 1.0 0.031 13.8 0.7 2.1 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) STAT_alpha PF01017.15 KFY01626.1 - 0.048 13.3 3.5 0.067 12.9 2.4 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain V_ATPase_I PF01496.14 KFY01626.1 - 0.055 11.3 1.1 0.063 11.1 0.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cytochrom_B562 PF07361.6 KFY01626.1 - 0.068 13.5 1.6 0.068 13.5 1.1 1.9 2 0 0 2 2 2 0 Cytochrome b562 TMP_2 PF06791.8 KFY01626.1 - 0.076 12.6 0.1 0.091 12.3 0.1 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein Tho2 PF11262.3 KFY01626.1 - 0.33 9.9 2.2 6 5.8 0.8 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 DUF4200 PF13863.1 KFY01626.1 - 0.84 9.5 7.8 1.2 9.0 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) AAA_32 PF13654.1 KFY01626.1 - 1.1 7.8 5.2 1.9 7.0 3.6 1.5 1 1 0 1 1 1 0 AAA domain Prefoldin PF02996.12 KFY01626.1 - 1.2 8.8 7.1 6.1 6.5 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit IncA PF04156.9 KFY01626.1 - 1.6 8.2 5.1 3.8 7.0 3.5 1.6 1 1 0 1 1 1 0 IncA protein DUF4337 PF14235.1 KFY01626.1 - 4 7.2 6.4 2.6 7.8 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) TMF_DNA_bd PF12329.3 KFY01626.1 - 4.2 7.2 12.3 0.73 9.6 2.3 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Cmc1 PF08583.5 KFY01627.1 - 1.7e-17 62.9 2.9 2e-17 62.7 2.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Flu_B_M2 PF04772.7 KFY01627.1 - 0.026 14.5 0.0 0.029 14.4 0.0 1.1 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) Tmemb_14 PF03647.8 KFY01628.1 - 1.4e-23 83.0 8.9 1.6e-23 82.8 6.2 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Transglut_core2 PF13369.1 KFY01628.1 - 0.098 12.1 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF2416 PF10315.4 KFY01628.1 - 0.1 12.8 2.3 0.26 11.5 1.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2416) GBP_PSP PF02425.10 KFY01628.1 - 0.53 9.8 2.3 0.95 9.0 1.6 1.4 1 0 0 1 1 1 0 Paralytic/GBP/PSP peptide DAD PF02109.11 KFY01629.1 - 3.9e-50 168.6 2.9 4.9e-50 168.3 2.0 1.1 1 0 0 1 1 1 1 DAD family DUF4389 PF14333.1 KFY01629.1 - 0.04 13.6 0.6 0.071 12.8 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4389) Zn_clus PF00172.13 KFY01630.1 - 8.9e-05 22.3 12.4 0.00015 21.6 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFY01630.1 - 0.00093 18.1 1.7 0.0023 16.8 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain ThiS PF02597.15 KFY01631.1 - 1.4e-10 41.4 0.0 2.8e-10 40.4 0.0 1.5 1 1 0 1 1 1 1 ThiS family RNB PF00773.14 KFY01632.1 - 1.6e-55 188.6 0.0 3.3e-55 187.6 0.0 1.5 1 1 0 1 1 1 1 RNB domain SprT-like PF10263.4 KFY01641.1 - 0.0023 17.5 0.1 0.0038 16.9 0.0 1.5 1 1 0 1 1 1 1 SprT-like family Peptidase_M50B PF13398.1 KFY01641.1 - 0.097 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like RGS PF00615.14 KFY01642.1 - 9.2e-12 45.1 0.0 1e-08 35.2 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain Ribosomal_L31e PF01198.14 KFY01643.1 - 1.3e-36 124.0 0.3 2.6e-36 123.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L31e UQ_con PF00179.21 KFY01644.1 - 5.1e-47 158.8 0.0 5.9e-47 158.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFY01644.1 - 0.00012 21.8 0.0 0.00014 21.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFY01644.1 - 0.00083 19.2 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KFY01644.1 - 0.0021 17.7 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 UEV domain Pkinase PF00069.20 KFY01645.1 - 8.2e-60 202.1 0.0 1.1e-59 201.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY01645.1 - 6.9e-25 87.5 0.0 9.2e-25 87.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFY01645.1 - 6.9e-07 28.4 0.0 9.8e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KFY01645.1 - 0.015 15.0 0.0 0.73 9.5 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KFY01645.1 - 0.025 13.6 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.2 KFY01646.1 - 3.3e-08 33.1 0.1 6.3e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFY01646.1 - 0.00013 21.5 0.7 0.00043 19.8 0.1 2.1 2 0 0 2 2 2 1 F-box domain PdxJ PF03740.8 KFY01647.1 - 0.039 13.1 0.1 0.05 12.7 0.1 1.1 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthesis protein PdxJ Saccharop_dh PF03435.13 KFY01648.1 - 3.5e-18 65.7 0.0 5e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase RRM_1 PF00076.17 KFY01648.1 - 7.2e-14 51.1 0.2 2e-13 49.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY01648.1 - 1.6e-10 40.8 0.0 3e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFY01648.1 - 1.8e-06 27.6 0.0 6e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Shikimate_DH PF01488.15 KFY01648.1 - 0.012 15.7 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 KFY01648.1 - 0.036 14.3 0.1 8.5 6.7 0.0 2.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain eIF-5a PF01287.15 KFY01653.1 - 1.4e-12 47.4 0.4 2.5e-12 46.5 0.2 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.7 KFY01653.1 - 0.071 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Vps52 PF04129.7 KFY01654.1 - 1.9e-119 399.5 0.3 3.7e-119 398.5 0.2 1.4 1 0 0 1 1 1 1 Vps52 / Sac2 family Ank_2 PF12796.2 KFY01654.1 - 3.3e-14 52.9 0.6 6.2e-07 29.6 0.1 5.7 4 2 0 4 4 4 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFY01654.1 - 8.1e-08 31.7 0.0 0.011 15.5 0.0 5.5 5 0 0 5 5 5 2 Ankyrin repeat NACHT PF05729.7 KFY01654.1 - 5.7e-06 26.0 0.0 2.4e-05 24.0 0.0 2.2 1 1 0 1 1 1 1 NACHT domain Ank_3 PF13606.1 KFY01654.1 - 2.7e-05 23.9 0.0 0.063 13.5 0.0 5.8 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.1 KFY01654.1 - 0.00022 21.3 0.0 2.4 8.5 0.0 5.1 4 1 1 5 5 5 1 Ankyrin repeats (many copies) AAA_22 PF13401.1 KFY01654.1 - 0.001 19.2 0.1 0.0058 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Ank_4 PF13637.1 KFY01654.1 - 0.0021 18.5 0.1 0.088 13.3 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Sec3_C PF09763.4 KFY01654.1 - 0.0036 15.5 0.2 0.0072 14.5 0.1 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec3 DUF1664 PF07889.7 KFY01654.1 - 0.0045 16.7 5.4 0.46 10.2 0.1 4.2 4 0 0 4 4 4 1 Protein of unknown function (DUF1664) DUF4349 PF14257.1 KFY01654.1 - 0.018 14.2 0.6 2.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) WEMBL PF05701.6 KFY01654.1 - 0.2 10.0 0.1 2.8 6.3 0.1 2.2 2 0 0 2 2 2 0 Weak chloroplast movement under blue light Carn_acyltransf PF00755.15 KFY01655.1 - 2.3e-173 577.5 0.0 2.6e-173 577.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Eaf7 PF07904.8 KFY01655.1 - 6.9e-27 93.2 0.1 1.4e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 DUF59 PF01883.14 KFY01657.1 - 1.3e-06 28.2 0.0 4e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function DUF59 zf-DHHC PF01529.15 KFY01658.1 - 2.3e-32 111.7 0.9 4.2e-32 110.9 0.6 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 KFY01658.1 - 0.035 13.8 0.9 0.084 12.6 0.7 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily NTF2 PF02136.15 KFY01667.1 - 3.2e-23 82.3 0.1 6e-23 81.4 0.1 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Prenyltransf PF01255.14 KFY01667.1 - 0.06 12.4 0.5 0.086 11.9 0.4 1.3 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Dicty_CAR PF05462.6 KFY01668.1 - 6.5e-17 61.3 8.6 1.1e-16 60.6 6.0 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.16 KFY01668.1 - 3.6e-08 32.8 0.0 5.8e-08 32.1 0.0 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.3 KFY01668.1 - 2.4e-06 27.2 11.3 4.2e-06 26.4 7.8 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Frizzled PF01534.12 KFY01668.1 - 0.091 11.5 13.7 9.8 4.8 9.5 2.3 1 1 0 1 1 1 0 Frizzled/Smoothened family membrane region DUF2207 PF09972.4 KFY01668.1 - 1.6 7.1 6.5 16 3.9 2.0 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) SAP PF02037.22 KFY01669.1 - 1.3e-13 50.0 0.0 2.4e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 KFY01669.1 - 0.0029 17.0 0.3 0.0096 15.4 0.2 1.9 1 1 0 1 1 1 1 HeH/LEM domain Armet PF10208.4 KFY01669.1 - 0.14 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding DUF2749 PF10907.3 KFY01669.1 - 0.61 9.9 3.4 2.5 8.0 1.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2749) Methyltransf_11 PF08241.7 KFY01671.1 - 0.15 12.6 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Sugar_tr PF00083.19 KFY01672.1 - 6e-113 377.7 23.2 6.9e-113 377.5 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY01672.1 - 1.5e-22 79.7 29.9 1.5e-22 79.7 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2264 PF10022.4 KFY01673.1 - 6.3e-126 419.8 0.0 7.8e-126 419.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) DNA_primase_lrg PF04104.9 KFY01674.1 - 8.1e-09 35.1 0.0 1.3e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Zn_clus PF00172.13 KFY01677.1 - 1.7e-05 24.5 9.3 3.9e-05 23.4 6.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3716 PF12511.3 KFY01677.1 - 0.15 11.6 4.8 0.31 10.6 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) AlaDh_PNT_N PF05222.10 KFY01681.1 - 4.6e-20 71.9 0.0 7.4e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KFY01681.1 - 9.7e-09 35.0 0.0 1.6e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Cys_Met_Meta_PP PF01053.15 KFY01682.1 - 5e-123 410.2 0.0 6e-123 409.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KFY01682.1 - 3.2e-05 22.8 0.0 6e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KFY01682.1 - 0.00069 18.6 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.11 KFY01682.1 - 0.019 13.7 0.0 0.036 12.7 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage system P-protein DegT_DnrJ_EryC1 PF01041.12 KFY01682.1 - 0.021 13.8 0.9 0.1 11.6 0.7 2.0 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ydc2-catalyt PF09159.5 KFY01684.1 - 6.8e-68 229.1 0.0 8.3e-68 228.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 KFY01684.1 - 7.1e-05 22.6 0.0 0.45 10.3 0.0 3.1 2 1 0 2 2 2 2 Poxvirus A22 protein SRP72 PF08492.7 KFY01684.1 - 0.051 13.9 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 SRP72 RNA-binding domain Herpes_UL49_5 PF05702.6 KFY01685.1 - 0.036 13.9 0.2 0.071 12.9 0.1 1.6 1 1 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein Mucin PF01456.12 KFY01685.1 - 0.15 11.8 9.5 0.18 11.6 6.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Myf5 PF12232.3 KFY01685.1 - 4.3 7.9 11.1 1.9 9.1 6.1 1.6 2 0 0 2 2 2 0 Myogenic determination factor 5 Septin PF00735.13 KFY01686.1 - 1.3e-111 372.1 0.3 1.5e-111 371.9 0.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KFY01686.1 - 6.4e-07 29.3 0.0 1.2e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KFY01686.1 - 4.2e-06 26.0 0.0 7.1e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 KFY01686.1 - 3.9e-05 22.8 0.0 6.9e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KFY01686.1 - 0.00053 19.8 0.5 1.3 8.8 0.0 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 KFY01686.1 - 0.00078 18.9 0.2 0.017 14.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 KFY01686.1 - 0.0027 18.0 0.0 0.0047 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KFY01686.1 - 0.003 17.0 0.0 0.0032 16.9 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 KFY01686.1 - 0.011 16.0 0.2 0.02 15.1 0.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 KFY01686.1 - 0.012 15.7 0.0 0.029 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 KFY01686.1 - 0.02 13.8 0.1 0.054 12.4 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.17 KFY01686.1 - 0.031 13.1 0.0 0.055 12.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain FtsK_SpoIIIE PF01580.13 KFY01686.1 - 0.033 13.6 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 KFY01686.1 - 0.034 14.1 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Gtr1_RagA PF04670.7 KFY01686.1 - 0.035 13.2 0.1 0.13 11.3 0.0 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Ribosomal_L32p PF01783.18 KFY01687.1 - 1.2e-12 47.7 2.0 2.2e-12 46.9 1.4 1.4 1 0 0 1 1 1 1 Ribosomal L32p protein family zinc-ribbons_6 PF07191.7 KFY01687.1 - 0.04 13.7 0.5 0.065 13.0 0.4 1.3 1 0 0 1 1 1 0 zinc-ribbons zf-ribbon_3 PF13248.1 KFY01687.1 - 0.44 9.8 3.2 0.87 8.8 2.2 1.5 1 1 0 1 1 1 0 zinc-ribbon domain WD40 PF00400.27 KFY01688.1 - 1.4e-30 104.0 11.4 9.1e-10 38.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KFY01688.1 - 9.9e-07 27.3 0.2 5.7e-06 24.8 0.1 1.8 1 1 0 1 1 1 1 Cytochrome D1 heme domain eIF2A PF08662.6 KFY01688.1 - 4.7e-05 23.1 0.0 0.0091 15.7 0.0 3.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 KFY01688.1 - 6.1e-05 22.2 0.4 0.055 12.5 0.0 3.4 1 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.9 KFY01688.1 - 0.0096 14.7 0.0 0.039 12.7 0.0 1.6 1 1 1 2 2 2 1 Coatomer WD associated region Nucleoporin_N PF08801.6 KFY01688.1 - 0.02 13.6 0.0 1 8.0 0.0 2.2 1 1 2 3 3 3 0 Nup133 N terminal like PPR_2 PF13041.1 KFY01689.1 - 1.9e-17 62.9 1.4 1.4e-05 24.9 0.0 5.5 3 2 2 5 5 5 4 PPR repeat family PPR_3 PF13812.1 KFY01689.1 - 6.2e-12 44.7 4.3 0.00067 19.7 0.0 5.5 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR PF01535.15 KFY01689.1 - 4.7e-11 41.8 4.1 6.5e-05 22.6 0.0 5.2 5 0 0 5 5 5 2 PPR repeat PPR_1 PF12854.2 KFY01689.1 - 0.015 14.7 5.2 0.031 13.7 0.0 3.5 4 1 0 4 4 4 0 PPR repeat MRP-S25 PF13741.1 KFY01690.1 - 4.5e-75 252.0 8.8 2.2e-73 246.5 6.1 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 SOG2 PF10428.4 KFY01691.1 - 2.9e-99 332.7 4.3 2.9e-99 332.7 3.0 3.1 4 0 0 4 4 4 1 RAM signalling pathway protein LRR_4 PF12799.2 KFY01691.1 - 6.3e-20 70.3 4.2 1.1e-08 34.4 0.7 3.6 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFY01691.1 - 2.3e-17 62.4 2.8 1e-10 41.1 0.7 3.0 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KFY01691.1 - 3.8e-10 38.3 4.7 0.17 11.9 0.1 5.9 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 KFY01691.1 - 3.5e-08 32.3 0.9 15 6.3 0.0 5.9 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 KFY01691.1 - 0.007 16.3 6.0 21 5.5 0.1 5.0 5 0 0 5 5 5 1 Leucine Rich repeat HemN_C PF06969.11 KFY01691.1 - 0.14 12.2 0.2 2.3 8.3 0.0 2.8 2 1 1 3 3 3 0 HemN C-terminal domain DUF605 PF04652.11 KFY01698.1 - 4.6 6.5 10.6 5.1 6.3 7.3 1.0 1 0 0 1 1 1 0 Vta1 like GTP_EFTU PF00009.22 KFY01699.1 - 7.8e-51 172.1 0.0 1.2e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 KFY01699.1 - 1.6e-21 76.1 3.3 3.3e-21 75.1 2.3 1.4 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D2 PF03144.20 KFY01699.1 - 1.2e-08 34.8 0.1 3.4e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFY01699.1 - 3.1e-08 33.5 0.1 2.4e-07 30.7 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.12 KFY01699.1 - 6.3e-08 32.6 0.0 2.1e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain Miro PF08477.8 KFY01699.1 - 8.4e-05 23.0 0.1 0.0015 19.0 0.0 2.6 2 1 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 KFY01699.1 - 0.027 13.6 0.0 1.9 7.6 0.0 2.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.13 KFY01699.1 - 0.051 12.5 0.0 0.088 11.8 0.0 1.3 1 0 0 1 1 1 0 Septin FeoB_N PF02421.13 KFY01699.1 - 0.18 11.0 0.2 1.9 7.7 0.0 2.5 2 1 0 2 2 2 0 Ferrous iron transport protein B HSP70 PF00012.15 KFY01700.1 - 3.5e-266 883.8 13.1 4e-266 883.7 9.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KFY01700.1 - 1.9e-16 59.5 1.8 3.8e-15 55.2 0.1 2.1 1 1 1 2 2 2 2 MreB/Mbl protein Radial_spoke_3 PF06098.6 KFY01700.1 - 0.0049 15.9 1.3 0.0049 15.9 0.9 1.6 2 0 0 2 2 2 1 Radial spoke protein 3 Hydantoinase_A PF01968.13 KFY01700.1 - 0.022 13.8 4.6 0.032 13.3 0.1 2.9 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.1 KFY01700.1 - 0.48 10.2 6.8 1 9.2 0.4 3.5 2 2 0 2 2 2 0 Cell division protein FtsA SelR PF01641.13 KFY01701.1 - 2.3e-49 166.1 0.1 3.2e-49 165.7 0.0 1.2 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 KFY01701.1 - 0.003 17.3 2.1 0.31 10.8 0.1 2.4 2 1 0 2 2 2 2 Double zinc ribbon GFA PF04828.9 KFY01701.1 - 0.0081 16.0 0.2 1.1 9.2 0.0 2.4 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme DUF2296 PF10058.4 KFY01701.1 - 0.051 13.3 0.5 0.94 9.2 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) TF_Zn_Ribbon PF08271.7 KFY01701.1 - 0.063 12.6 0.8 2.2 7.6 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Yippee-Mis18 PF03226.9 KFY01701.1 - 0.2 11.7 0.5 0.77 9.8 0.4 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF3262 PF11660.3 KFY01702.1 - 0.038 14.0 1.3 0.071 13.2 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3262) Synaptobrevin PF00957.16 KFY01702.1 - 0.055 13.0 0.3 2.3 7.8 0.0 2.0 1 1 1 2 2 2 0 Synaptobrevin SNARE PF05739.14 KFY01702.1 - 0.06 13.0 0.0 0.091 12.4 0.0 1.3 1 1 0 1 1 1 0 SNARE domain DUF500 PF04366.7 KFY01703.1 - 1.8e-45 153.4 0.2 4.2e-45 152.2 0.2 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF500) SH3_2 PF07653.12 KFY01703.1 - 9.2e-15 53.8 0.1 3.7e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KFY01703.1 - 1.1e-14 53.5 0.2 4.8e-14 51.4 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 KFY01703.1 - 1.6e-13 49.9 0.1 3.3e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF3176 PF11374.3 KFY01705.1 - 0.0051 16.6 1.0 0.013 15.3 0.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) AA_permease_2 PF13520.1 KFY01706.1 - 7.6e-43 146.6 56.4 1.7e-42 145.4 39.1 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFY01706.1 - 2.6e-21 75.5 47.3 3.8e-21 74.9 32.8 1.1 1 0 0 1 1 1 1 Amino acid permease Ras PF00071.17 KFY01707.1 - 6.3e-44 149.2 0.0 8.4e-44 148.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFY01707.1 - 5.3e-11 43.0 0.0 8e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFY01707.1 - 2.7e-05 23.4 0.0 4.5e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KFY01707.1 - 0.021 14.0 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KFY01707.1 - 0.17 11.0 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PAP2 PF01569.16 KFY01708.1 - 1.4e-16 60.3 4.0 2.5e-16 59.5 2.3 1.7 1 1 0 1 1 1 1 PAP2 superfamily RabGAP-TBC PF00566.13 KFY01710.1 - 2e-50 171.2 0.1 3.1e-50 170.6 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain adh_short_C2 PF13561.1 KFY01711.1 - 3.3e-26 92.5 0.3 4.1e-26 92.2 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFY01711.1 - 2.1e-25 89.5 0.3 3.6e-25 88.8 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFY01711.1 - 9.7e-09 35.1 0.6 3.3e-08 33.4 0.3 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KFY01711.1 - 0.00011 21.6 0.1 0.00014 21.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TB PF00683.12 KFY01712.1 - 0.064 12.8 0.9 0.1 12.1 0.6 1.3 1 0 0 1 1 1 0 TB domain PGPGW PF09656.5 KFY01729.1 - 0.12 11.6 0.6 0.26 10.5 0.4 1.6 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) HSP70 PF00012.15 KFY01733.1 - 1e-10 40.2 0.4 8.8e-10 37.1 0.1 1.9 2 0 0 2 2 2 1 Hsp70 protein zf-SAP30 PF13866.1 KFY01733.1 - 0.0075 15.8 0.1 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 KFY01733.1 - 0.019 13.6 0.1 0.15 10.6 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein PLA2_B PF01735.13 KFY01734.1 - 5.9e-194 644.8 6.1 7.2e-194 644.5 4.3 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Ion_trans_2 PF07885.11 KFY01736.1 - 4.4e-33 112.8 18.6 2e-17 62.6 4.2 3.4 3 0 0 3 3 3 2 Ion channel adh_short PF00106.20 KFY01736.1 - 3.1e-12 46.7 0.6 5.4e-12 45.9 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFY01736.1 - 2.2e-07 30.7 1.2 3e-07 30.2 0.3 1.6 2 0 0 2 2 2 1 KR domain DUF360 PF04020.8 KFY01736.1 - 0.012 15.9 1.9 0.012 15.9 1.3 3.2 3 0 0 3 3 3 0 Membrane protein of unknown function Adeno_E3B PF03376.9 KFY01737.1 - 0.19 11.6 0.3 0.47 10.3 0.0 1.7 2 0 0 2 2 2 0 Adenovirus E3B protein DUF488 PF04343.8 KFY01741.1 - 2.6e-18 66.5 0.0 4e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF488 SPX PF03105.14 KFY01742.1 - 8.6e-50 170.0 0.2 8.6e-50 170.0 0.2 2.3 2 0 0 2 2 2 1 SPX domain Na_sulph_symp PF00939.14 KFY01742.1 - 1.5e-31 109.7 45.9 2.3e-31 109.2 31.8 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 KFY01742.1 - 2.3e-13 49.4 26.0 2.3e-13 49.4 18.0 2.7 1 1 2 3 3 3 2 Citrate transporter Nucleoplasmin PF03066.10 KFY01742.1 - 1.8 8.0 7.7 4.3 6.8 0.8 2.3 2 0 0 2 2 2 0 Nucleoplasmin Diphthamide_syn PF01866.12 KFY01743.1 - 3.2e-113 378.0 0.0 4e-113 377.6 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein ATP-synt_ab PF00006.20 KFY01744.1 - 1.1e-60 204.8 0.0 1.7e-60 204.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain HMGL-like PF00682.14 KFY01744.1 - 1.7e-39 135.9 0.0 3.7e-39 134.7 0.0 1.6 1 1 0 1 1 1 1 HMGL-like ATP-synt_ab_C PF00306.22 KFY01744.1 - 2.9e-14 53.4 0.2 5.9e-14 52.4 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KFY01744.1 - 3.5e-11 43.1 1.0 3.5e-11 43.1 0.7 2.3 3 0 0 3 3 3 1 ATP synthase alpha/beta family, beta-barrel domain WPP PF13943.1 KFY01744.1 - 0.067 13.4 0.1 2 8.6 0.0 2.8 2 0 0 2 2 2 0 WPP domain Aminotran_3 PF00202.16 KFY01745.1 - 1.6e-96 323.1 0.0 2e-96 322.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Steroid_dh PF02544.11 KFY01746.1 - 3.8e-24 85.1 0.6 5.3e-24 84.7 0.4 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 KFY01746.1 - 0.0065 16.5 0.6 0.0065 16.5 0.4 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 KFY01746.1 - 0.096 11.9 3.1 0.13 11.5 1.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) RabGAP-TBC PF00566.13 KFY01747.1 - 6.6e-47 159.7 0.1 1.7e-45 155.1 0.0 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Microtub_assoc PF07989.6 KFY01747.1 - 0.071 12.9 12.8 0.054 13.3 2.4 3.0 2 1 1 3 3 3 0 Microtubule associated DUF972 PF06156.8 KFY01747.1 - 1.1 9.6 16.2 3.8 7.9 2.1 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ATG16 PF08614.6 KFY01747.1 - 4.2 7.1 32.3 13 5.5 2.3 3.8 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) ADIP PF11559.3 KFY01747.1 - 9.3 6.1 19.4 12 5.8 7.0 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding F-box PF00646.28 KFY01755.1 - 2.2e-05 23.9 0.0 2.2e-05 23.9 0.0 2.4 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 KFY01755.1 - 0.00016 21.3 0.2 0.00058 19.5 0.0 1.9 2 0 0 2 2 2 1 F-box-like DUF4524 PF15025.1 KFY01755.1 - 0.00068 19.1 0.1 0.0024 17.3 0.0 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4524) F-box-like_2 PF13013.1 KFY01755.1 - 0.024 14.3 0.2 0.042 13.5 0.2 1.5 1 1 0 1 1 1 0 F-box-like domain DZR PF12773.2 KFY01755.1 - 0.74 9.6 5.9 22 4.9 4.1 2.8 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 KFY01755.1 - 0.88 9.5 4.4 3.8 7.5 1.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 KFY01755.1 - 1.2 8.9 12.5 7.6 6.4 2.3 3.4 2 1 1 3 3 3 0 Transposase zinc-ribbon domain PHD_2 PF13831.1 KFY01755.1 - 1.9 7.8 7.7 17 4.7 0.0 3.6 4 0 0 4 4 4 0 PHD-finger Aldedh PF00171.17 KFY01756.1 - 5e-154 513.0 1.0 6.2e-154 512.7 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 KFY01756.1 - 0.0095 15.1 0.0 0.04 13.1 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) OmdA PF13376.1 KFY01756.1 - 0.077 12.6 0.1 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated DUF2435 PF10363.4 KFY01757.1 - 1.8e-16 59.8 0.0 9.5e-16 57.4 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 KFY01757.1 - 5.4e-08 32.1 0.2 1.2e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) DASH_Dad3 PF08656.5 KFY01758.1 - 3.6e-26 90.6 0.3 4.5e-26 90.3 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 Ribosomal_S5_C PF03719.10 KFY01759.1 - 2.9e-17 61.6 0.0 5.9e-17 60.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 KFY01759.1 - 3.6e-11 42.6 0.1 7e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain tRNA_U5-meth_tr PF05958.6 KFY01760.1 - 4.8e-11 41.9 0.0 2.3e-09 36.4 0.0 2.8 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.5 KFY01760.1 - 9.5e-07 28.5 0.0 1.6e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.1 KFY01760.1 - 2e-05 24.2 0.0 3.6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KFY01760.1 - 0.0029 16.7 0.0 0.0044 16.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KFY01760.1 - 0.0073 16.3 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KFY01760.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_18 PF12847.2 KFY01760.1 - 0.015 15.8 0.0 0.031 14.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UNC45-central PF11701.3 KFY01761.1 - 1.1e-41 142.0 0.0 1.8e-39 134.9 0.0 3.4 2 1 0 2 2 2 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 KFY01761.1 - 4.5e-08 33.2 9.7 0.0053 17.0 0.4 5.7 5 1 0 5 5 5 3 HEAT repeats Arm PF00514.18 KFY01761.1 - 0.00027 20.6 20.8 0.18 11.7 0.0 8.4 8 1 0 8 8 8 2 Armadillo/beta-catenin-like repeat Tfb4 PF03850.9 KFY01762.1 - 3.1e-106 354.6 0.0 3.5e-106 354.4 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 KFY01762.1 - 0.0071 16.4 0.2 0.013 15.5 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Actin PF00022.14 KFY01764.1 - 1.8e-88 296.6 0.0 3.5e-88 295.7 0.0 1.4 1 1 0 1 1 1 1 Actin ADH_N PF08240.7 KFY01764.1 - 1.2e-29 102.2 0.6 1.2e-29 102.2 0.4 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFY01764.1 - 5.4e-24 84.2 0.1 1.5e-23 82.7 0.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFY01764.1 - 0.001 19.9 0.1 0.0024 18.7 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KFY01764.1 - 0.011 14.8 0.1 0.02 14.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glucokinase PF02685.11 KFY01764.1 - 0.094 11.4 0.5 0.19 10.5 0.3 1.4 1 0 0 1 1 1 0 Glucokinase Asparaginase_2 PF01112.13 KFY01765.1 - 1.1e-34 119.5 0.6 4.9e-19 68.2 0.0 2.3 2 0 0 2 2 2 2 Asparaginase GDPD PF03009.12 KFY01766.1 - 1.8e-70 237.3 0.0 3.3e-70 236.5 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 KFY01766.1 - 5.9e-34 116.2 5.8 3.1e-14 53.0 0.1 4.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFY01766.1 - 1.2e-29 102.1 2.3 1.1e-11 44.9 0.0 5.7 5 0 0 5 5 5 4 Ankyrin repeats (many copies) SPX PF03105.14 KFY01766.1 - 4.3e-29 102.1 2.7 2.6e-16 60.2 0.3 3.4 1 1 1 2 2 2 2 SPX domain Ank PF00023.25 KFY01766.1 - 1.4e-25 87.7 2.0 8.8e-07 28.4 0.0 7.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 KFY01766.1 - 3.8e-21 74.6 1.3 1.8e-08 34.3 0.0 6.0 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY01766.1 - 6.6e-19 66.1 2.0 0.00039 20.3 0.0 7.4 6 0 0 6 6 6 4 Ankyrin repeat RicinB_lectin_2 PF14200.1 KFY01767.1 - 4.4e-07 30.2 0.3 0.00074 19.8 0.0 2.3 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like CTP_transf_1 PF01148.15 KFY01767.1 - 0.036 13.7 0.0 0.047 13.3 0.0 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family PPR_3 PF13812.1 KFY01768.1 - 2.3e-05 24.3 0.7 0.09 13.0 0.0 4.3 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 KFY01768.1 - 0.012 15.5 0.1 0.53 10.2 0.0 2.6 2 1 1 3 3 3 0 PPR repeat family PPR PF01535.15 KFY01768.1 - 0.16 12.0 0.1 16 5.7 0.1 2.9 3 0 0 3 3 3 0 PPR repeat DUF866 PF05907.8 KFY01769.1 - 1.9e-47 160.7 0.0 2.9e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) LSM PF01423.17 KFY01769.1 - 1.3e-18 66.3 0.2 1.9e-18 65.7 0.1 1.3 1 0 0 1 1 1 1 LSM domain PRMT5 PF05185.11 KFY01770.1 - 9.8e-172 571.8 0.0 1.2e-171 571.5 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase AMP-binding PF00501.23 KFY01771.1 - 8.8e-82 274.7 0.0 1.3e-81 274.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PS-DH PF14765.1 KFY01771.1 - 1.9e-53 181.5 0.0 2.6e-53 181.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 KFY01771.1 - 2.7e-50 170.5 0.1 7.9e-50 169.0 0.1 1.9 1 0 0 1 1 1 1 KR domain Condensation PF00668.15 KFY01771.1 - 5.4e-44 150.2 0.1 9.4e-44 149.4 0.1 1.4 1 0 0 1 1 1 1 Condensation domain adh_short PF00106.20 KFY01771.1 - 8e-42 142.9 0.1 3.4e-40 137.6 0.0 2.8 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KFY01771.1 - 5.1e-23 81.2 0.0 1.4e-21 76.5 0.0 3.1 2 1 0 2 2 2 1 Male sterility protein Methyltransf_12 PF08242.7 KFY01771.1 - 5.4e-20 71.7 0.0 1.9e-19 69.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 KFY01771.1 - 3.3e-17 62.5 0.0 2.5e-08 34.1 0.0 2.7 1 1 1 2 2 2 2 HxxPF-repeated domain PP-binding PF00550.20 KFY01771.1 - 4.6e-16 58.8 1.4 7.9e-07 29.2 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 KFY01771.1 - 1.2e-14 54.3 0.0 2.5e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY01771.1 - 1.6e-12 47.2 0.0 4e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY01771.1 - 2.5e-12 47.1 0.0 9.9e-12 45.1 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY01771.1 - 1.3e-09 38.5 0.1 1.1e-08 35.5 0.0 2.7 3 0 0 3 3 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFY01771.1 - 4.1e-07 29.3 0.0 1e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Epimerase PF01370.16 KFY01771.1 - 3.1e-06 26.8 0.0 6.1e-05 22.5 0.0 2.8 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family Methyltransf_16 PF10294.4 KFY01771.1 - 1.6e-05 24.4 0.0 3.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.15 KFY01771.1 - 0.00037 19.6 0.0 0.00081 18.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase 3Beta_HSD PF01073.14 KFY01771.1 - 0.00043 19.0 0.0 0.66 8.6 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_26 PF13659.1 KFY01771.1 - 0.00096 19.1 0.0 0.0028 17.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 KFY01771.1 - 0.0031 16.4 0.1 0.0067 15.3 0.0 1.5 1 0 0 1 1 1 1 DREV methyltransferase NodS PF05401.6 KFY01771.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) PCMT PF01135.14 KFY01771.1 - 0.28 10.6 0.0 0.65 9.4 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Sugar_tr PF00083.19 KFY01772.1 - 3.5e-23 81.9 28.4 1.6e-13 50.0 6.5 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter DUF3611 PF12263.3 KFY01772.1 - 0.057 12.8 6.1 0.023 14.0 0.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3611) PBD PF00786.23 KFY01773.1 - 0.00011 22.5 0.0 0.0003 21.1 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Isy1 PF06246.7 KFY01785.1 - 6.8e-79 264.8 0.9 6.8e-79 264.8 0.6 1.6 2 0 0 2 2 2 1 Isy1-like splicing family Metallophos PF00149.23 KFY01785.1 - 1.5e-10 40.7 0.4 4.8e-10 39.1 0.0 2.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFY01785.1 - 7.6e-07 29.0 0.2 1.3e-06 28.3 0.2 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MMR_HSR1 PF01926.18 KFY01786.1 - 4.2e-13 49.2 0.0 8.1e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KFY01786.1 - 0.00035 19.7 0.0 0.00091 18.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 KFY01786.1 - 0.0011 18.2 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KFY01786.1 - 0.012 15.4 0.3 1.1 9.0 0.0 2.6 1 1 1 2 2 2 0 Dynamin family AAA_16 PF13191.1 KFY01786.1 - 0.074 13.0 0.0 0.58 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KFY01786.1 - 0.1 12.7 0.1 15 5.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain IIGP PF05049.8 KFY01786.1 - 0.19 10.5 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Abhydrolase_1 PF00561.15 KFY01787.1 - 1.3e-17 64.1 0.0 5.6e-16 58.8 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFY01787.1 - 4.3e-11 43.1 1.5 4e-10 39.9 1.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KFY01787.1 - 9e-06 25.2 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Glyco_hydro_3 PF00933.16 KFY01788.1 - 2.9e-89 298.9 0.0 4.4e-89 298.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFY01788.1 - 1.2e-56 191.7 0.1 3.6e-56 190.2 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFY01788.1 - 2e-20 72.4 0.0 3.7e-20 71.6 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PAN_2 PF08276.6 KFY01789.1 - 0.0013 18.5 0.0 0.0035 17.1 0.0 1.7 1 0 0 1 1 1 1 PAN-like domain PAN_1 PF00024.21 KFY01789.1 - 0.034 13.9 0.0 0.092 12.5 0.0 1.7 1 0 0 1 1 1 0 PAN domain ThiF PF00899.16 KFY01790.1 - 2.9e-37 127.5 0.1 4.9e-37 126.7 0.1 1.3 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.1 KFY01790.1 - 8.1e-05 22.8 0.1 0.00018 21.7 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Saccharop_dh PF03435.13 KFY01790.1 - 0.00014 20.9 0.6 0.00039 19.5 0.4 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase ApbA PF02558.11 KFY01790.1 - 0.01 15.2 0.1 0.018 14.5 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 KFY01790.1 - 0.017 15.0 0.2 0.055 13.4 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 KFY01790.1 - 0.02 14.2 0.0 0.06 12.7 0.0 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 KFY01790.1 - 0.021 13.7 0.1 0.038 12.8 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KFY01790.1 - 0.046 13.3 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.5 KFY01790.1 - 0.053 13.1 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 KR domain NAD_Gly3P_dh_N PF01210.18 KFY01790.1 - 0.087 12.5 0.0 0.21 11.3 0.0 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 KFY01790.1 - 0.14 12.2 0.1 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 KFY01792.1 - 8.2e-11 41.7 0.2 2.1e-10 40.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFY01792.1 - 8.2e-08 31.5 1.0 1.5e-07 30.6 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFY01792.1 - 2.7e-07 29.8 1.9 1.1e-06 27.8 0.7 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFY01792.1 - 4.7e-07 30.1 0.3 9.9e-07 29.0 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFY01792.1 - 9.1e-07 29.1 0.3 6.3e-05 23.1 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KFY01792.1 - 2e-06 27.1 3.0 3.8e-06 26.2 2.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFY01792.1 - 2.1e-06 27.7 0.0 0.00042 20.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFY01792.1 - 1.5e-05 23.6 0.6 2.7e-05 22.8 0.4 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 KFY01792.1 - 0.00016 20.9 0.7 0.00028 20.0 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KFY01792.1 - 0.0011 18.1 0.1 0.002 17.2 0.1 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 KFY01792.1 - 0.0033 16.3 0.1 0.0048 15.8 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KFY01792.1 - 0.0059 15.5 0.1 0.0095 14.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein K_oxygenase PF13434.1 KFY01792.1 - 0.013 14.4 0.2 2.2 7.1 0.1 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) IlvN PF07991.7 KFY01792.1 - 0.051 12.9 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Amino_oxidase PF01593.19 KFY01792.1 - 0.064 12.3 0.0 0.093 11.7 0.0 1.4 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase GATase_3 PF07685.9 KFY01792.1 - 0.14 11.7 0.0 6.3 6.3 0.0 2.3 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain ApbA PF02558.11 KFY01792.1 - 0.89 8.9 3.5 2.4 7.6 0.6 2.6 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA AAA_12 PF13087.1 KFY01793.1 - 7.2e-37 126.7 0.0 2.6e-36 124.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KFY01793.1 - 1.9e-25 89.8 0.9 2e-24 86.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KFY01793.1 - 2.8e-10 40.1 0.0 5.7e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KFY01793.1 - 4.2e-09 36.0 0.0 1.3e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 KFY01793.1 - 6.1e-07 29.1 0.0 0.022 14.3 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 KFY01793.1 - 0.0033 17.2 0.0 0.0096 15.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KFY01793.1 - 0.012 14.6 0.3 0.52 9.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 KFY01793.1 - 0.032 13.4 0.0 0.061 12.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein WD40 PF00400.27 KFY01794.1 - 9.2e-16 57.0 7.2 0.00095 18.9 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat 2OG-FeII_Oxy PF03171.15 KFY01794.1 - 1.8e-13 50.5 0.0 3.5e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KFY01794.1 - 2e-06 28.3 0.0 4.4e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Fungal_trans_2 PF11951.3 KFY01795.1 - 7.9e-11 41.1 0.1 6e-08 31.6 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain ADH_zinc_N PF00107.21 KFY01796.1 - 2.3e-12 46.6 0.0 6.6e-12 45.1 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFY01796.1 - 3.4e-10 40.9 0.0 7.1e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFY01796.1 - 5.3e-06 26.1 1.2 0.00035 20.3 0.6 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Eno-Rase_NADH_b PF12242.3 KFY01796.1 - 0.021 14.5 0.2 0.068 12.9 0.0 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KFY01796.1 - 0.046 13.7 0.1 0.07 13.1 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding 2-Hacid_dh_C PF02826.14 KFY01796.1 - 0.16 11.1 0.2 0.74 8.9 0.0 2.0 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.2 KFY01797.1 - 8e-32 110.9 0.0 9.7e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY01797.1 - 7.4e-19 68.2 0.0 4.2e-18 65.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFY01797.1 - 6.3e-10 38.9 0.0 2.2e-09 37.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFY01797.1 - 0.00017 21.3 0.0 0.0014 18.4 0.0 2.3 1 1 1 2 2 2 1 Putative lysophospholipase DUF1057 PF06342.7 KFY01797.1 - 0.00025 19.9 0.0 0.00045 19.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) EHN PF06441.7 KFY01797.1 - 0.053 13.4 0.3 1.1 9.2 0.0 2.8 3 0 0 3 3 3 0 Epoxide hydrolase N terminus Ribonuclease PF00545.15 KFY01798.1 - 0.11 12.5 5.9 0.7 10.0 4.1 2.0 1 1 0 1 1 1 0 ribonuclease DUF3632 PF12311.3 KFY01799.1 - 1.2e-34 119.7 1.1 1.6e-19 70.4 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3632) BRCA-2_helical PF09169.5 KFY01799.1 - 0.15 11.6 0.2 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 BRCA2, helical E1-E2_ATPase PF00122.15 KFY01801.1 - 6.3e-47 159.5 3.9 1e-46 158.8 2.7 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFY01801.1 - 9.9e-30 104.5 0.0 2.9e-29 103.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 KFY01801.1 - 3.8e-27 94.9 0.3 3.8e-27 94.9 0.2 3.3 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 KFY01801.1 - 2.3e-18 65.9 0.0 5.3e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KFY01801.1 - 6.2e-14 52.6 0.0 1.5e-13 51.3 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFY01801.1 - 3.2e-07 29.6 0.0 9.1e-07 28.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus MtrG PF04210.8 KFY01801.1 - 0.026 14.1 0.6 2.3 7.9 0.2 2.8 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G WD40 PF00400.27 KFY01802.1 - 1.1e-80 262.8 13.6 3.1e-09 36.3 0.0 11.8 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp13 PF08625.6 KFY01802.1 - 2.5e-46 156.8 0.1 3.9e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 KFY01802.1 - 2.1e-09 36.0 9.7 0.037 12.1 0.0 5.9 2 2 0 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFY01802.1 - 4.8e-07 28.8 2.9 0.23 10.1 0.0 5.6 5 1 0 6 6 6 2 Nup133 N terminal like DUF763 PF05559.6 KFY01802.1 - 0.064 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF763) KAR9 PF08580.5 KFY01803.1 - 0.66 8.1 3.7 0.89 7.7 2.6 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF1237 PF06824.6 KFY01804.1 - 1e-180 600.9 0.0 1.2e-180 600.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) MFS_1 PF07690.11 KFY01804.1 - 8.3e-29 100.3 48.9 3.3e-26 91.8 22.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_47 PF01532.15 KFY01805.1 - 4.5e-136 454.1 0.0 5.2e-136 453.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 FMO-like PF00743.14 KFY01806.1 - 6.9e-42 143.3 0.0 6.8e-27 93.8 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFY01806.1 - 4.8e-18 65.9 0.4 8.3e-17 61.9 0.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFY01806.1 - 1.2e-12 47.8 0.2 3.2e-10 39.9 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KFY01806.1 - 3.2e-12 46.7 0.0 3.7e-10 40.0 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFY01806.1 - 5.4e-12 45.2 1.3 4.6e-09 35.6 0.1 2.7 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KFY01806.1 - 5.4e-09 35.9 0.2 4.3e-07 29.8 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFY01806.1 - 6.8e-09 35.1 0.1 2.2e-05 23.6 0.0 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 KFY01806.1 - 7.3e-07 28.4 1.3 0.003 16.5 0.0 3.9 4 0 0 4 4 4 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFY01806.1 - 3.9e-06 27.1 0.2 0.031 14.6 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFY01806.1 - 0.001 17.6 4.5 0.0033 15.9 0.1 2.4 3 0 0 3 3 3 1 HI0933-like protein Shikimate_DH PF01488.15 KFY01806.1 - 0.0017 18.4 0.2 0.85 9.7 0.1 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 KFY01806.1 - 0.0079 15.9 0.1 0.76 9.4 0.1 2.3 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_2 PF00890.19 KFY01806.1 - 0.011 14.5 1.1 0.37 9.5 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 KFY01806.1 - 0.016 14.1 0.7 1.2 7.9 0.0 2.5 2 0 0 2 2 2 0 Lycopene cyclase protein Amino_oxidase PF01593.19 KFY01806.1 - 0.024 13.7 0.0 0.051 12.6 0.0 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.17 KFY01806.1 - 0.032 13.0 1.4 2.2 7.0 0.0 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KFY01806.1 - 0.036 13.1 0.2 0.32 10.0 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.2 KFY01806.1 - 0.049 12.7 1.5 0.078 12.0 0.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KFY01806.1 - 0.049 13.2 0.4 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KFY01806.1 - 0.06 12.4 0.0 3.9 6.5 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Malic_M PF03949.10 KFY01806.1 - 0.088 12.3 0.1 4.5 6.7 0.0 2.4 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain NAD_binding_7 PF13241.1 KFY01806.1 - 0.12 12.6 0.1 29 4.9 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyridox_ox_2 PF12900.2 KFY01807.1 - 2.2e-37 128.0 0.0 2.9e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase UCH PF00443.24 KFY01809.1 - 1.5e-21 76.7 0.0 2.1e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFY01809.1 - 2.5e-11 43.5 0.4 4.8e-11 42.6 0.3 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 KFY01809.1 - 0.03 13.7 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 KFY01810.1 - 2.2e-32 109.7 7.0 1.1e-08 34.5 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 KFY01810.1 - 0.024 12.7 0.0 1 7.4 0.0 2.5 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFY01810.1 - 0.047 12.4 0.1 0.44 9.2 0.0 2.3 2 1 0 2 2 2 0 Nup133 N terminal like Nha1_C PF08619.5 KFY01810.1 - 0.13 11.5 10.7 0.2 10.8 7.4 1.3 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Proteasome PF00227.21 KFY01811.1 - 2.8e-30 105.0 0.0 3.1e-30 104.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Viral_DNA_bp PF00747.12 KFY01811.1 - 0.085 10.0 0.0 0.11 9.7 0.0 1.0 1 0 0 1 1 1 0 ssDNA binding protein DEAD PF00270.24 KFY01812.1 - 5.7e-45 152.8 0.0 1.3e-43 148.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFY01812.1 - 3.7e-28 97.2 0.1 7.1e-28 96.2 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 KFY01812.1 - 0.1 10.9 0.0 0.18 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) CMS1 PF14617.1 KFY01812.1 - 0.18 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Pec_lyase_C PF00544.14 KFY01813.1 - 4.7e-20 71.9 5.1 8.9e-20 71.0 3.5 1.4 1 0 0 1 1 1 1 Pectate lyase DUF3445 PF11927.3 KFY01814.1 - 5.4e-64 215.9 0.0 9.5e-62 208.6 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3445) Acetyltransf_3 PF13302.1 KFY01814.1 - 1.7e-20 73.6 0.0 5e-20 72.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KFY01814.1 - 0.00065 19.6 0.0 0.1 12.4 0.0 2.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFY01814.1 - 0.02 14.6 0.0 11 5.8 0.0 3.0 3 0 0 3 3 3 0 FR47-like protein Acetyltransf_1 PF00583.19 KFY01814.1 - 0.062 13.3 0.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family DNA_pol_E_B PF04042.11 KFY01816.1 - 1.9e-50 171.0 0.0 2.5e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF899 PF05988.7 KFY01817.1 - 1e-48 165.5 0.0 1.4e-48 165.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AA_permease PF00324.16 KFY01818.1 - 2.6e-56 190.9 36.1 3.3e-56 190.6 25.0 1.1 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 KFY01819.1 - 2.8e-82 276.3 33.0 3.4e-82 276.1 22.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Arf PF00025.16 KFY01838.1 - 1.6e-74 248.9 0.1 1.8e-74 248.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KFY01838.1 - 4.5e-13 48.9 0.0 5e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KFY01838.1 - 2.6e-12 46.1 2.4 6.9e-09 34.8 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KFY01838.1 - 1.3e-11 44.0 0.0 1.6e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KFY01838.1 - 7.5e-10 38.3 0.0 8.9e-10 38.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KFY01838.1 - 8e-07 29.5 0.0 1.1e-06 29.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFY01838.1 - 0.00021 21.2 0.0 0.00027 20.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KFY01838.1 - 0.025 13.6 0.1 0.04 13.0 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DegQ PF08181.6 KFY01838.1 - 0.07 12.8 0.7 0.14 11.8 0.5 1.5 1 0 0 1 1 1 0 DegQ (SacQ) family DUF3986 PF13143.1 KFY01838.1 - 0.14 12.6 0.7 0.78 10.2 0.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Ank_2 PF12796.2 KFY01839.1 - 1.2e-106 349.2 21.3 8.4e-22 77.3 0.2 8.2 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 KFY01839.1 - 8.4e-86 277.8 8.6 4.4e-06 26.2 0.0 13.9 14 0 0 14 14 14 12 Ankyrin repeat Ank_3 PF13606.1 KFY01839.1 - 5.4e-66 211.9 3.0 0.0003 20.7 0.0 13.5 14 0 0 14 14 14 12 Ankyrin repeat Ank_4 PF13637.1 KFY01839.1 - 1.1e-56 188.2 1.1 6.3e-09 36.1 0.0 9.6 3 2 7 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY01839.1 - 4.4e-56 185.6 14.6 3.2e-07 30.3 0.0 12.1 2 2 11 13 13 13 12 Ankyrin repeats (many copies) NACHT PF05729.7 KFY01839.1 - 3.9e-08 33.1 0.0 9.8e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KFY01839.1 - 1.8e-06 28.0 0.1 7.2e-06 26.1 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain Torsin PF06309.6 KFY01839.1 - 0.15 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Torsin MCM PF00493.18 KFY01840.1 - 3.4e-131 436.9 0.0 5.4e-131 436.3 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 KFY01840.1 - 1.7e-35 122.3 40.8 1.7e-35 122.3 28.2 2.4 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 KFY01840.1 - 2.9e-20 72.9 0.1 7.7e-20 71.5 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFY01840.1 - 2.2e-08 33.5 0.0 2e-06 27.1 0.0 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KFY01840.1 - 0.00013 21.6 0.0 0.00048 19.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 KFY01840.1 - 0.00068 19.1 0.1 0.27 10.6 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.6 KFY01840.1 - 0.0019 17.8 0.0 0.0068 16.0 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 KFY01840.1 - 0.069 13.2 0.0 0.24 11.4 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain zf-TFIIB PF13453.1 KFY01840.1 - 0.1 11.7 1.4 0.22 10.7 1.0 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger zf-UBR PF02207.15 KFY01841.1 - 1.1e-15 57.0 3.1 1.1e-15 57.0 2.2 2.9 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) AA_permease_2 PF13520.1 KFY01842.1 - 2.1e-64 217.6 45.4 2.8e-64 217.2 31.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFY01842.1 - 1.9e-22 79.2 40.3 2.5e-22 78.8 27.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3493 PF11998.3 KFY01842.1 - 1.7 8.6 6.1 1.1 9.1 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3493) Malic_M PF03949.10 KFY01843.1 - 5.3e-84 281.7 0.0 9.5e-84 280.9 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KFY01843.1 - 1.1e-71 240.2 0.0 1.7e-71 239.5 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain AlaDh_PNT_C PF01262.16 KFY01843.1 - 0.11 12.0 0.4 0.32 10.5 0.1 1.9 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Ribosomal_L18p PF00861.17 KFY01844.1 - 2.7e-43 146.9 0.1 4.6e-43 146.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KFY01844.1 - 7.7e-30 103.3 9.9 7.7e-30 103.3 6.8 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region HAD_2 PF13419.1 KFY01845.1 - 2.4e-15 57.2 0.0 9.3e-15 55.2 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFY01845.1 - 0.019 14.6 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like SNF2_N PF00176.18 KFY01847.1 - 3.3e-12 45.8 0.0 3.4e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain GATase PF00117.23 KFY01848.1 - 1.1e-09 38.0 0.0 1.8e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Pyr_redox_3 PF13738.1 KFY01848.1 - 0.0084 16.1 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GATase_3 PF07685.9 KFY01848.1 - 0.066 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain IpaC_SipC PF09599.5 KFY01848.1 - 4.2 6.2 6.0 7.3 5.4 4.2 1.3 1 0 0 1 1 1 0 Salmonella-Shigella invasin protein C (IpaC_SipC) Sugar_tr PF00083.19 KFY01849.1 - 1.2e-106 357.0 20.5 1.4e-106 356.8 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY01849.1 - 2.9e-32 111.7 42.9 8.6e-30 103.6 14.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 KFY01849.1 - 0.00014 20.7 0.6 0.00031 19.5 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF791) Methyltransf_25 PF13649.1 KFY01850.1 - 1.1e-13 51.3 0.0 1.8e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY01850.1 - 1.6e-13 50.5 0.0 1.9e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY01850.1 - 1.1e-12 48.4 0.0 1.7e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFY01850.1 - 7.1e-12 45.3 0.0 8.5e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFY01850.1 - 7.9e-11 42.0 0.0 1.3e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY01850.1 - 1.9e-09 37.9 0.0 2.8e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFY01850.1 - 1.3e-07 30.9 0.0 1.8e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KFY01850.1 - 4.3e-07 30.3 0.0 6.6e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KFY01850.1 - 1.9e-05 23.5 0.0 2.5e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.6 KFY01850.1 - 0.0086 15.4 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.8 KFY01850.1 - 0.0095 15.0 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Pox_MCEL PF03291.11 KFY01850.1 - 0.012 14.4 0.0 0.042 12.7 0.0 1.7 1 1 0 1 1 1 0 mRNA capping enzyme PCMT PF01135.14 KFY01850.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 KFY01850.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.1 KFY01850.1 - 0.045 13.4 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 KFY01850.1 - 0.089 12.3 0.0 0.19 11.2 0.0 1.5 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Peptidase_C2 PF00648.16 KFY01851.1 - 5.3e-57 193.0 1.2 5e-37 127.5 0.3 2.5 2 0 0 2 2 2 2 Calpain family cysteine protease DUF3543 PF12063.3 KFY01854.1 - 1.2e-84 283.2 0.1 2.2e-84 282.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 KFY01854.1 - 1.4e-61 207.9 0.0 2.3e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY01854.1 - 3.9e-43 147.3 0.0 7.8e-43 146.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KFY01854.1 - 0.088 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Hemerythrin PF01814.18 KFY01861.1 - 5.2e-12 46.0 0.6 7.6e-12 45.5 0.4 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain POR PF01558.13 KFY01861.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.7 1 1 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Romo1 PF10247.4 KFY01871.1 - 6.4e-27 93.5 13.0 8.4e-27 93.1 9.0 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.14 KFY01871.1 - 0.4 10.7 7.9 0.73 9.8 5.4 1.4 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_OmpA PF13436.1 KFY01871.1 - 4 7.1 5.4 25 4.5 3.8 2.0 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 KFY01871.1 - 5.9 6.4 8.9 1.2 8.6 3.1 2.0 1 1 1 2 2 2 0 YMGG-like Gly-zipper MFS_1 PF07690.11 KFY01879.1 - 5.2e-30 104.3 28.3 5.2e-30 104.3 19.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily adh_short PF00106.20 KFY01879.1 - 1.4e-25 90.0 6.0 1.1e-13 51.4 1.7 2.7 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KFY01879.1 - 4.9e-10 39.5 0.3 9.1e-05 22.3 0.0 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFY01879.1 - 6.2e-08 32.5 6.3 3.1e-06 26.9 2.1 3.2 1 1 1 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KFY01879.1 - 5e-06 26.6 0.6 1.3e-05 25.3 0.1 1.8 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KFY01879.1 - 1.3e-05 24.7 0.1 2.3e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFY01879.1 - 0.0002 20.2 0.2 0.00031 19.5 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KFY01879.1 - 0.012 14.4 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.8 KFY01879.1 - 0.027 13.7 0.3 0.052 12.7 0.2 1.5 1 0 0 1 1 1 0 NmrA-like family DUF2530 PF10745.4 KFY01879.1 - 0.031 14.2 0.2 0.14 12.1 0.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) TrkA_N PF02254.13 KFY01879.1 - 0.044 13.7 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 KFY01879.1 - 0.11 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cullin PF00888.17 KFY01880.1 - 4.9e-126 421.6 2.2 4.9e-126 421.6 1.5 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 KFY01880.1 - 2.8e-27 94.3 2.4 7e-27 93.0 1.7 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain zf-DNL PF05180.7 KFY01881.1 - 1.6e-29 101.3 0.6 2.3e-29 100.8 0.4 1.2 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 KFY01881.1 - 0.042 13.3 0.2 0.08 12.4 0.2 1.5 1 0 0 1 1 1 0 CSL zinc finger Elf1 PF05129.8 KFY01881.1 - 0.074 12.7 0.3 0.12 12.0 0.2 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.1 KFY01881.1 - 0.33 10.6 2.7 3.6 7.3 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KFY01881.1 - 0.5 9.9 2.9 4.6 6.9 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DRIM PF07539.7 KFY01882.1 - 2e-42 143.9 0.1 6.6e-42 142.2 0.1 2.0 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT PF02985.17 KFY01882.1 - 0.019 15.0 0.6 2.4 8.4 0.0 5.1 5 0 0 5 5 5 0 HEAT repeat Arm PF00514.18 KFY01882.1 - 0.023 14.5 2.1 23 5.0 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat CwfJ_C_1 PF04677.10 KFY01883.1 - 3.9e-26 91.1 0.0 7e-26 90.2 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KFY01883.1 - 1.8e-24 86.0 0.4 4.6e-24 84.7 0.1 1.7 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 Ppx-GppA PF02541.11 KFY01884.1 - 4.9e-41 140.7 0.0 6.5e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family ADP_PFK_GK PF04587.10 KFY01885.1 - 0.088 11.0 0.0 0.13 10.4 0.0 1.2 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Sld5 PF05916.6 KFY01886.1 - 8.5e-07 29.2 0.1 1.4e-06 28.5 0.1 1.3 1 0 0 1 1 1 1 GINS complex protein WD40 PF00400.27 KFY01887.1 - 5.6e-65 213.0 22.2 9.6e-13 47.4 0.0 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 KFY01887.1 - 1.5e-09 37.8 0.1 0.046 13.4 0.0 4.2 2 1 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFY01887.1 - 9.7e-07 27.2 1.9 0.23 9.5 0.0 4.9 1 1 3 5 5 5 3 Nucleoporin Nup120/160 DUF1513 PF07433.6 KFY01887.1 - 1.4e-06 27.3 1.1 0.31 9.9 0.1 4.2 2 1 2 4 4 4 3 Protein of unknown function (DUF1513) Nucleoporin_N PF08801.6 KFY01887.1 - 0.00043 19.1 1.1 0.56 8.8 0.0 4.2 2 2 1 4 4 4 1 Nup133 N terminal like PD40 PF07676.7 KFY01887.1 - 0.027 14.1 0.9 2.6 7.8 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 KFY01887.1 - 0.11 10.6 0.0 0.3 9.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Mago-bind PF09282.5 KFY01888.1 - 6e-13 48.0 3.2 1.3e-12 47.0 2.2 1.6 1 0 0 1 1 1 1 Mago binding T4SS PF07996.6 KFY01888.1 - 0.031 14.1 4.2 0.046 13.5 2.9 1.2 1 0 0 1 1 1 0 Type IV secretion system proteins RR_TM4-6 PF06459.7 KFY01888.1 - 0.37 10.6 12.1 0.45 10.3 8.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec6 PF06046.8 KFY01888.1 - 0.47 8.4 3.2 0.59 8.1 2.2 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec6 UCR_UQCRX_QCR9 PF05365.7 KFY01889.1 - 1.2e-25 88.8 2.7 1.5e-25 88.5 1.9 1.3 1 1 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-UBR PF02207.15 KFY01890.1 - 1.9e-18 65.9 14.4 4.6e-18 64.7 10.0 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Exo_endo_phos PF03372.18 KFY01890.1 - 3.5e-14 53.3 0.0 6.1e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ClpS PF02617.12 KFY01890.1 - 8.6e-07 28.5 0.1 1.8e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS Mito_fiss_reg PF05308.6 KFY01890.1 - 0.078 12.3 2.7 0.17 11.1 1.9 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 KFY01890.1 - 0.088 12.0 5.0 0.16 11.2 3.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal IU_nuc_hydro PF01156.14 KFY01891.1 - 4.2e-77 259.4 0.1 6.8e-77 258.7 0.0 1.4 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase RED_N PF07808.8 KFY01891.1 - 4.5e-08 32.5 4.6 1.1e-07 31.3 3.2 1.6 1 0 0 1 1 1 1 RED-like protein N-terminal region ApoO PF09769.4 KFY01892.1 - 7.1e-45 152.5 2.7 6.6e-44 149.4 0.0 2.7 2 1 1 3 3 3 2 Apolipoprotein O Peptidase_M3 PF01432.15 KFY01893.1 - 1.1e-123 413.6 0.0 2e-123 412.8 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M3 DUF2421 PF10334.4 KFY01893.1 - 0.044 13.3 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2421) Peptidase_M50B PF13398.1 KFY01893.1 - 0.066 12.5 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Rad51 PF08423.6 KFY01896.1 - 8.6e-139 460.6 0.0 1.1e-138 460.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KFY01896.1 - 4.8e-14 52.2 0.0 7.1e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 KFY01896.1 - 5.4e-07 29.6 0.6 1.1e-06 28.7 0.1 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain RecA PF00154.16 KFY01896.1 - 1e-06 28.0 0.0 1.4e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 KFY01896.1 - 1.6e-06 27.4 0.0 3.2e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 KaiC PAXNEB PF05625.6 KFY01896.1 - 0.064 12.0 0.0 0.16 10.8 0.0 1.5 2 0 0 2 2 2 0 PAXNEB protein DnaB_C PF03796.10 KFY01896.1 - 0.13 11.1 0.0 0.25 10.1 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Nup160 PF11715.3 KFY01897.1 - 3.8e-133 444.5 0.0 5.9e-133 443.8 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Ribosomal_L29 PF00831.18 KFY01898.1 - 1.4e-17 63.1 0.4 1.4e-17 63.1 0.3 1.8 2 1 0 2 2 2 1 Ribosomal L29 protein SPATA24 PF15175.1 KFY01898.1 - 0.023 14.3 6.0 0.27 10.9 0.3 2.1 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 Spc42p PF11544.3 KFY01898.1 - 0.22 11.5 2.9 0.25 11.2 1.3 1.6 1 1 1 2 2 2 0 Spindle pole body component Spc42p Syntaxin_2 PF14523.1 KFY01899.1 - 0.063 13.3 0.0 0.075 13.0 0.0 1.1 1 0 0 1 1 1 0 Syntaxin-like protein DNA_binding_1 PF01035.15 KFY01906.1 - 4.6e-18 64.7 0.0 5.4e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain ACOX PF01756.14 KFY01907.1 - 8.1e-35 119.8 0.1 2e-34 118.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 KFY01907.1 - 2.1e-25 89.4 0.0 4.5e-25 88.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 KFY01907.1 - 1.5e-11 43.6 0.2 1.5e-11 43.6 0.2 2.1 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KFY01907.1 - 2.9e-06 27.4 0.6 0.00039 20.5 0.4 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ABC2_membrane PF01061.19 KFY01908.1 - 1.7e-28 99.2 29.1 1.7e-28 99.2 20.2 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 KFY01908.1 - 1.5e-26 93.3 0.0 2.3e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFY01908.1 - 6.8e-09 36.0 0.6 2.5e-06 27.6 0.4 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFY01908.1 - 4.3e-05 23.5 0.0 7.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFY01908.1 - 4.8e-05 23.5 0.0 0.00018 21.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KFY01908.1 - 0.00011 21.4 0.0 0.00028 20.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 KFY01908.1 - 0.00021 22.0 0.0 0.00053 20.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 KFY01908.1 - 0.0018 17.5 0.5 0.12 11.5 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KFY01908.1 - 0.0027 17.1 0.0 0.0085 15.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 KFY01908.1 - 0.0028 16.7 0.0 0.4 9.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KFY01908.1 - 0.0031 17.0 0.1 0.0067 15.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 KFY01908.1 - 0.0047 17.2 0.0 0.0095 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 KFY01908.1 - 0.0047 15.8 0.0 0.0078 15.1 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.24 KFY01908.1 - 0.0059 16.8 0.2 0.071 13.3 0.0 2.5 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.1 KFY01908.1 - 0.015 13.8 0.5 0.24 9.8 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KFY01908.1 - 0.027 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFY01908.1 - 0.028 14.3 0.1 0.065 13.1 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_10 PF12846.2 KFY01908.1 - 0.029 13.8 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain cobW PF02492.14 KFY01908.1 - 0.029 13.8 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 KFY01908.1 - 0.12 12.2 0.0 0.29 11.1 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.1 KFY01908.1 - 0.13 12.5 0.1 0.34 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KFY01908.1 - 0.13 12.1 0.0 0.4 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KFY01908.1 - 0.13 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC2_membrane_3 PF12698.2 KFY01908.1 - 0.16 10.9 26.6 0.43 9.5 18.5 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein ketoacyl-synt PF00109.21 KFY01909.1 - 8.3e-78 261.3 0.0 1.5e-77 260.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KFY01909.1 - 5.7e-43 147.4 0.0 1.1e-41 143.1 0.0 2.2 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KFY01909.1 - 6.1e-34 116.4 0.0 1.6e-33 115.0 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 KFY01909.1 - 6.7e-31 108.2 0.0 1.5e-30 107.1 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 KFY01909.1 - 7.7e-24 83.7 6.1 3.1e-11 43.3 0.1 3.4 3 0 0 3 3 3 2 Phosphopantetheine attachment site PS-DH PF14765.1 KFY01909.1 - 3.5e-13 49.3 0.0 5.5e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.2 KFY01909.1 - 3.1e-05 23.9 0.2 0.00025 20.9 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFY01909.1 - 0.00015 21.5 0.0 0.12 12.1 0.0 2.8 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 KFY01909.1 - 0.00074 18.5 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF2974 PF11187.3 KFY01909.1 - 0.037 13.3 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) MFS_1 PF07690.11 KFY01910.1 - 3.6e-36 124.6 32.1 3.6e-36 124.6 22.2 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1673 PF07895.6 KFY01910.1 - 3.3 7.1 6.4 0.23 10.9 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) APH PF01636.18 KFY01911.1 - 2.3e-07 30.7 0.0 1.5e-06 28.1 0.0 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KFY01911.1 - 0.1 11.5 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase Bromodomain PF00439.20 KFY01912.1 - 4.3e-14 52.1 0.0 1.5e-13 50.4 0.0 1.9 1 1 0 1 1 1 1 Bromodomain DUF2280 PF10045.4 KFY01912.1 - 0.16 11.8 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2280) ATG16 PF08614.6 KFY01913.1 - 0.015 15.1 0.1 0.027 14.3 0.1 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TBPIP PF07106.8 KFY01913.1 - 0.023 14.2 0.1 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SlyX PF04102.7 KFY01913.1 - 0.1 12.9 0.1 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 SlyX IncA PF04156.9 KFY01913.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 IncA protein Striatin PF08232.7 KFY01913.1 - 0.21 11.8 4.8 0.49 10.7 3.3 1.7 1 1 0 1 1 1 0 Striatin family tRNA-synt_1 PF00133.17 KFY01915.1 - 2.6e-38 131.4 0.0 1.6e-27 95.8 0.0 3.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KFY01915.1 - 1.4e-18 66.7 0.0 4.7e-12 45.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KFY01915.1 - 1.5e-11 44.2 0.1 3.4e-11 43.1 0.1 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KFY01915.1 - 9.3e-08 31.5 0.0 1.7e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Auxin_repressed PF05564.7 KFY01915.1 - 0.08 13.5 0.4 0.21 12.2 0.1 1.8 2 0 0 2 2 2 0 Dormancy/auxin associated protein tRNA-synt_1_2 PF13603.1 KFY01915.1 - 0.1 11.8 0.8 10 5.3 0.0 2.9 3 0 0 3 3 3 0 Leucyl-tRNA synthetase, Domain 2 Clat_adaptor_s PF01217.15 KFY01917.1 - 1.7e-41 141.2 0.1 6.4e-41 139.3 0.0 1.7 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Frataxin_Cyay PF01491.11 KFY01918.1 - 4.9e-35 119.6 0.0 5.8e-35 119.3 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain zf-CSL PF05207.8 KFY01919.1 - 6.5e-24 83.1 0.3 7.6e-24 82.9 0.2 1.1 1 0 0 1 1 1 1 CSL zinc finger ABC_membrane_2 PF06472.10 KFY01920.1 - 1.8e-108 361.9 2.5 3e-108 361.2 1.7 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KFY01920.1 - 1.3e-17 64.4 0.0 3.1e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFY01920.1 - 0.00059 19.8 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KFY01920.1 - 0.0094 16.2 0.1 0.17 12.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFY01920.1 - 0.013 15.4 0.4 0.055 13.4 0.1 2.1 3 0 0 3 3 3 0 AAA ATPase domain SMC_N PF02463.14 KFY01920.1 - 0.045 12.9 0.2 0.23 10.6 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFY01920.1 - 0.053 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.7 KFY01920.1 - 0.081 11.9 0.0 0.47 9.4 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus DUF258 PF03193.11 KFY01920.1 - 0.11 11.7 0.0 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Mg_chelatase PF01078.16 KFY01920.1 - 0.16 11.0 0.1 0.46 9.6 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MFS_1 PF07690.11 KFY01921.1 - 4.5e-32 111.1 38.1 5.6e-32 110.8 26.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily KbaA PF14089.1 KFY01921.1 - 0.53 9.8 6.5 0.035 13.6 0.8 1.7 2 0 0 2 2 2 0 KinB-signalling pathway activation in sporulation Methyltransf_23 PF13489.1 KFY01922.1 - 3.1e-06 27.0 0.0 0.00023 20.8 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 KFY01922.1 - 2.6e-05 24.7 0.1 6.4e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY01922.1 - 0.00042 19.9 0.1 0.029 13.9 0.0 2.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 KFY01922.1 - 0.0092 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 KFY01922.1 - 0.017 14.2 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 KFY01922.1 - 0.021 15.3 0.1 2.3 8.7 0.0 2.7 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 KFY01922.1 - 0.04 12.9 0.0 0.14 11.2 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.9 KFY01922.1 - 0.084 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Beta_elim_lyase PF01212.16 KFY01923.1 - 1.8e-52 178.2 0.0 2.1e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.14 KFY01923.1 - 0.014 13.9 0.0 0.02 13.3 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Sugar_tr PF00083.19 KFY01924.1 - 4.8e-119 397.8 35.9 3.6e-112 375.2 13.1 3.5 4 1 0 4 4 4 2 Sugar (and other) transporter MFS_1 PF07690.11 KFY01924.1 - 2.2e-68 230.5 102.8 5.1e-41 140.5 25.7 3.7 2 2 2 4 4 4 3 Major Facilitator Superfamily Aldolase_II PF00596.16 KFY01925.1 - 2.1e-45 154.6 0.3 3.7e-45 153.7 0.2 1.4 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain MFS_1 PF07690.11 KFY01925.1 - 5e-13 48.5 26.6 7.9e-13 47.8 18.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Dus PF01207.12 KFY01929.1 - 3.2e-42 144.4 0.1 4.3e-42 144.0 0.1 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 KFY01929.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein Ldh_2 PF02615.9 KFY01930.1 - 6.2e-62 209.2 0.1 7.7e-62 208.9 0.1 1.1 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase NAD_binding_2 PF03446.10 KFY01931.1 - 5.2e-34 117.4 0.0 6.7e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KFY01931.1 - 1.7e-18 66.8 0.0 2.8e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 KFY01931.1 - 0.00026 21.3 0.0 0.0011 19.3 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 KFY01931.1 - 0.014 15.8 0.0 0.027 14.9 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold dDENN PF03455.14 KFY01933.1 - 0.036 14.1 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 dDENN domain Lactamase_B_2 PF12706.2 KFY01934.1 - 7.5e-07 28.8 0.4 1e-06 28.4 0.3 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KFY01934.1 - 2.3e-06 27.3 1.8 2.3e-05 24.1 0.1 2.3 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily CMD PF02627.15 KFY01935.1 - 2.3e-20 72.1 0.3 7.1e-20 70.6 0.0 1.8 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family DUF4128 PF13554.1 KFY01935.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage related domain of unknown function MFS_1 PF07690.11 KFY01936.1 - 2e-27 95.8 31.4 2.8e-27 95.3 21.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4473 PF14747.1 KFY01936.1 - 0.023 14.9 0.5 0.046 13.9 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) FAD_binding_2 PF00890.19 KFY01937.1 - 1e-40 139.9 0.0 6.5e-40 137.2 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KFY01937.1 - 9.4e-11 41.4 0.1 8.9e-08 31.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase DAO PF01266.19 KFY01937.1 - 9.1e-10 37.9 0.7 1.8e-09 36.9 0.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFY01937.1 - 5.8e-06 25.0 5.8 0.0015 17.1 0.1 3.1 3 0 0 3 3 3 3 HI0933-like protein Pyr_redox_2 PF07992.9 KFY01937.1 - 5e-05 23.2 1.6 0.0075 16.1 1.1 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFY01937.1 - 0.00097 18.0 5.5 0.0086 14.9 0.3 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KFY01937.1 - 0.0052 15.8 0.1 0.059 12.4 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KFY01937.1 - 0.015 15.2 0.6 0.048 13.7 0.4 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.14 KFY01937.1 - 0.022 13.9 0.3 0.17 11.0 0.2 2.0 2 0 0 2 2 2 0 GMC oxidoreductase Pyr_redox_3 PF13738.1 KFY01937.1 - 0.024 14.6 0.9 0.79 9.7 0.6 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFY01937.1 - 0.15 11.1 0.6 0.37 9.8 0.0 1.9 2 0 0 2 2 2 0 Thi4 family Alginate_lyase2 PF08787.6 KFY01937.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Alginate lyase Aldedh PF00171.17 KFY01938.1 - 3e-152 507.2 0.1 3.3e-152 507.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFY01938.1 - 0.0081 14.9 0.2 0.019 13.7 0.2 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Fungal_trans PF04082.13 KFY01939.1 - 1.4e-23 83.1 0.0 2.3e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY01939.1 - 1.3e-07 31.4 13.2 2.5e-07 30.4 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.17 KFY01940.1 - 2e-131 438.5 0.1 2.3e-131 438.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFY01940.1 - 0.016 13.9 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Cullin PF00888.17 KFY01941.1 - 2.8e-52 178.0 0.0 5.2e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 KFY01941.1 - 7e-18 64.6 0.2 2.2e-17 63.0 0.1 2.0 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 FeoC PF09012.5 KFY01941.1 - 0.064 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 FeoC like transcriptional regulator Sugar_tr PF00083.19 KFY01942.1 - 4.7e-115 384.7 15.2 7.7e-115 384.0 10.5 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY01942.1 - 4.2e-25 88.2 42.9 2.3e-23 82.5 14.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFY01942.1 - 0.00037 18.8 3.6 0.00037 18.8 2.5 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) YrhC PF14143.1 KFY01942.1 - 0.2 11.5 1.0 14 5.7 0.0 2.9 3 0 0 3 3 3 0 YrhC-like protein zf-C2H2_4 PF13894.1 KFY01943.1 - 0.0035 17.5 6.1 0.23 11.8 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFY01943.1 - 0.012 15.9 9.6 0.098 13.0 0.6 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type HR1 PF02185.11 KFY01947.1 - 0.0011 18.6 0.4 0.0011 18.6 0.3 3.5 4 1 0 4 4 4 1 Hr1 repeat Reo_sigmaC PF04582.7 KFY01947.1 - 0.019 14.1 2.5 0.13 11.3 0.3 2.3 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DUF4618 PF15397.1 KFY01947.1 - 0.023 14.0 0.1 0.023 14.0 0.1 3.0 3 2 0 3 3 3 0 Domain of unknown function (DUF4618) DUF4439 PF14530.1 KFY01947.1 - 0.37 11.2 4.7 4 7.9 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4439) BLOC1_2 PF10046.4 KFY01947.1 - 0.54 10.4 6.2 2.3 8.3 0.4 3.7 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IMD PF08397.6 KFY01947.1 - 0.69 9.1 12.3 1.4 8.1 1.8 2.4 2 0 0 2 2 2 0 IRSp53/MIM homology domain Fib_alpha PF08702.5 KFY01947.1 - 0.93 9.6 18.6 0.41 10.7 3.5 3.2 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Uds1 PF15456.1 KFY01947.1 - 1.4 8.9 20.5 0.12 12.3 2.0 3.0 2 1 1 3 3 3 0 Up-regulated During Septation Lzipper-MIP1 PF14389.1 KFY01947.1 - 4.7 7.3 16.5 3.9 7.6 0.7 4.2 4 1 1 5 5 5 0 Leucine-zipper of ternary complex factor MIP1 Spore_YhcN_YlaJ PF09580.5 KFY01947.1 - 6 6.9 9.8 20 5.2 6.8 2.0 1 1 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) FlaC_arch PF05377.6 KFY01947.1 - 8.3 6.3 10.8 14 5.6 0.5 4.6 2 1 3 5 5 5 0 Flagella accessory protein C (FlaC) PGI PF00342.14 KFY01951.1 - 2.4e-217 722.1 2.6 2.7e-217 721.9 1.8 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Cys_Met_Meta_PP PF01053.15 KFY01952.1 - 1.9e-134 447.8 0.0 2.2e-134 447.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KFY01952.1 - 2.9e-07 29.7 0.0 4.6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KFY01952.1 - 2.9e-05 23.0 0.0 6.9e-05 21.7 0.0 1.6 1 1 1 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KFY01952.1 - 0.00061 18.9 0.0 0.002 17.2 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KFY01952.1 - 0.0011 18.2 0.0 0.0068 15.5 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase POTRA_2 PF08479.6 KFY01952.1 - 0.0032 17.0 0.0 0.0087 15.7 0.0 1.7 1 0 0 1 1 1 1 POTRA domain, ShlB-type Abhydrolase_6 PF12697.2 KFY01953.1 - 6.7e-20 71.9 0.0 9e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFY01953.1 - 1.9e-07 30.9 0.0 3.3e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KFY01953.1 - 0.002 17.7 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Peptidase_S9 PF00326.16 KFY01953.1 - 0.0034 16.6 0.1 0.0052 16.0 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KFY01953.1 - 0.0062 16.1 0.1 0.022 14.3 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold PE-PPE PF08237.6 KFY01953.1 - 0.052 12.9 0.1 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain Lipase_2 PF01674.13 KFY01953.1 - 0.15 11.3 0.1 0.25 10.6 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 2) HATPase_c PF02518.21 KFY01954.1 - 2.7e-21 75.3 0.2 4.9e-21 74.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KFY01954.1 - 2.2e-20 72.7 0.0 2.8e-19 69.1 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KFY01954.1 - 7e-12 45.1 0.1 2e-11 43.6 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 KFY01954.1 - 4.6e-05 23.5 0.0 0.00019 21.5 0.0 2.1 2 0 0 2 2 2 1 GAF domain MS_channel PF00924.13 KFY01954.1 - 0.024 13.9 0.0 0.077 12.3 0.0 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel Cutinase PF01083.17 KFY01955.1 - 2.6e-49 167.3 12.7 3e-49 167.1 8.8 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KFY01955.1 - 7e-05 22.3 0.5 0.00011 21.7 0.2 1.4 1 1 0 1 1 1 1 PE-PPE domain DUF3089 PF11288.3 KFY01955.1 - 0.0058 15.8 0.0 0.0086 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) GHMP_kinases_N PF00288.21 KFY01955.1 - 0.044 13.8 1.4 0.45 10.6 0.7 2.4 2 0 0 2 2 2 0 GHMP kinases N terminal domain NAD_binding_10 PF13460.1 KFY01958.1 - 1.6e-06 28.2 0.0 2.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFY01958.1 - 2.3e-06 27.2 0.0 0.022 14.1 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KFY01958.1 - 7.9e-06 26.1 0.0 1.4e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KFY01958.1 - 0.00026 19.9 0.0 0.023 13.6 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.8 KFY01958.1 - 0.00038 19.7 0.0 0.00064 19.0 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family UPF0183 PF03676.9 KFY01959.1 - 3.6e-28 98.2 0.0 2.1e-26 92.4 0.0 2.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) Kinesin PF00225.18 KFY01960.1 - 7.3e-108 360.2 0.2 7.3e-108 360.2 0.2 2.3 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bind PF13931.1 KFY01960.1 - 8.9e-11 42.1 3.8 8.9e-11 42.1 2.6 5.3 3 2 2 6 6 6 1 Kinesin-associated microtubule-binding Glyoxalase_4 PF13669.1 KFY01960.1 - 0.072 13.1 0.9 1 9.4 0.0 2.5 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Baculo_PEP_C PF04513.7 KFY01960.1 - 8.8 6.1 33.1 0.62 9.8 0.1 6.3 3 1 4 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus tRNA-synt_1 PF00133.17 KFY01961.1 - 6.4e-163 542.9 0.0 9e-163 542.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KFY01961.1 - 5.9e-21 74.5 0.1 3.3e-10 39.1 0.0 3.7 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KFY01961.1 - 6.2e-17 61.7 0.0 1.3e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Fungal_trans_2 PF11951.3 KFY01961.1 - 3.8e-06 25.7 2.4 0.00032 19.4 0.1 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain tRNA-synt_1_2 PF13603.1 KFY01961.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.9 KFY01961.1 - 0.034 13.8 0.2 0.071 12.7 0.1 1.5 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS IL6 PF00489.12 KFY01961.1 - 0.065 12.8 0.1 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 Interleukin-6/G-CSF/MGF family tRNA-synt_1e PF01406.14 KFY01961.1 - 0.19 10.8 0.0 10 5.1 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Lysine_decarbox PF03641.9 KFY01962.1 - 4e-13 49.3 0.0 3.7e-07 30.0 0.0 2.2 2 0 0 2 2 2 2 Possible lysine decarboxylase WD40 PF00400.27 KFY01963.1 - 7e-155 498.1 36.1 3.7e-14 51.9 0.1 13.4 13 0 0 13 13 13 12 WD domain, G-beta repeat PD40 PF07676.7 KFY01963.1 - 4.2e-13 48.6 1.4 13 5.5 0.0 10.8 11 0 0 11 11 11 3 WD40-like Beta Propeller Repeat NACHT PF05729.7 KFY01963.1 - 1.9e-12 47.1 0.4 3.9e-12 46.1 0.3 1.5 1 0 0 1 1 1 1 NACHT domain DUF1258 PF06869.7 KFY01963.1 - 0.0019 17.3 1.7 3.6 6.5 0.0 5.1 2 2 3 6 6 6 1 Protein of unknown function (DUF1258) PepSY_2 PF13670.1 KFY01984.1 - 0.15 11.9 0.4 0.28 11.1 0.3 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DIM PF08194.7 KFY01984.1 - 0.17 11.8 1.2 2.9 7.9 0.1 2.2 2 0 0 2 2 2 0 DIM protein Fic PF02661.13 KFY01985.1 - 4.1e-20 72.2 0.0 1.9e-19 70.1 0.0 2.1 3 0 0 3 3 3 1 Fic/DOC family PH PF00169.24 KFY01986.1 - 2.3e-11 43.7 0.0 5e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 PH domain Prominin PF05478.6 KFY01986.1 - 0.009 13.6 0.5 0.014 12.9 0.4 1.2 1 0 0 1 1 1 1 Prominin tRNA-synt_2b PF00587.20 KFY01987.1 - 4.2e-46 156.6 0.4 7.1e-46 155.9 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KFY01987.1 - 6.8e-19 67.6 0.0 1.8e-18 66.2 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 KFY01987.1 - 6e-13 48.4 0.0 1.5e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 KFY01987.1 - 8.6e-13 47.9 0.0 1.9e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Gar1 PF04410.9 KFY01988.1 - 2.7e-42 143.8 0.4 1.1e-41 141.8 0.0 1.8 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region DUF2013 PF09431.5 KFY01989.1 - 8.7e-50 168.1 5.4 8.7e-50 168.1 3.7 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2013) RHH_4 PF13467.1 KFY01989.1 - 0.039 13.8 0.1 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 Ribbon-helix-helix domain DnaJ PF00226.26 KFY01990.1 - 9.5e-22 76.5 1.3 9.5e-22 76.5 0.9 2.7 3 0 0 3 3 3 1 DnaJ domain TPR_11 PF13414.1 KFY01990.1 - 1.2e-18 66.5 0.4 7.3e-10 38.3 0.0 5.0 3 3 2 5 5 5 3 TPR repeat TPR_1 PF00515.23 KFY01990.1 - 7.7e-15 53.7 0.0 0.0014 18.1 0.0 5.5 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 KFY01990.1 - 1.1e-13 49.9 0.3 0.092 12.7 0.0 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFY01990.1 - 3.8e-10 40.1 0.2 0.065 13.9 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFY01990.1 - 1.7e-08 33.5 3.2 0.15 11.8 0.0 6.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFY01990.1 - 5.3e-08 33.0 0.3 0.062 13.6 0.0 5.0 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFY01990.1 - 1.3e-07 31.3 0.9 0.037 13.9 0.0 5.3 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFY01990.1 - 5.9e-07 29.1 0.0 0.039 14.1 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFY01990.1 - 2.3e-06 27.3 0.2 0.17 11.7 0.1 3.7 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFY01990.1 - 2.7e-06 27.5 0.0 2.1 9.2 0.0 6.3 2 2 6 8 8 8 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFY01990.1 - 2.8e-06 27.3 0.0 0.16 12.5 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFY01990.1 - 3.2e-06 26.5 0.1 0.036 13.8 0.0 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Transcrip_act PF04949.8 KFY01990.1 - 0.033 13.7 1.9 0.52 9.9 0.1 2.6 2 0 0 2 2 2 0 Transcriptional activator DUF1732 PF08340.6 KFY01991.1 - 0.1 12.4 0.5 0.33 10.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1732) CENP-F_leu_zip PF10473.4 KFY01991.1 - 0.11 12.3 3.0 2.6 7.8 0.6 2.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Vac14_Fig4_bd PF11916.3 KFY01992.1 - 1e-82 275.7 7.4 1e-82 275.7 5.1 2.2 3 0 0 3 3 3 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 KFY01992.1 - 5.2e-47 158.1 0.0 7.7e-44 148.0 0.0 4.1 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 KFY01992.1 - 2.4e-09 36.4 3.3 0.00039 20.2 0.0 6.2 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 KFY01992.1 - 5.9e-09 36.1 6.3 0.0017 18.7 0.1 5.9 4 1 1 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.1 KFY01992.1 - 2.1e-08 34.3 3.8 0.0032 17.7 0.0 5.2 5 0 0 5 5 5 1 HEAT repeats CLASP_N PF12348.3 KFY01992.1 - 0.0056 16.0 0.1 0.9 8.8 0.0 3.6 3 1 1 4 4 4 1 CLASP N terminal Arm PF00514.18 KFY01992.1 - 0.0097 15.7 0.1 12 5.8 0.0 4.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat DUF824 PF05688.6 KFY01995.1 - 0.1 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Salmonella repeat of unknown function (DUF824) Fungal_trans PF04082.13 KFY01999.1 - 1.7e-29 102.5 0.9 2.8e-29 101.7 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY01999.1 - 2.1e-08 33.9 14.9 4.7e-08 32.8 10.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Striatin PF08232.7 KFY01999.1 - 0.092 13.0 2.3 1 9.7 0.0 2.5 2 0 0 2 2 2 0 Striatin family SET PF00856.23 KFY02000.1 - 1.4e-06 28.7 0.0 3.1e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 SET domain MMR_HSR1_C PF08438.5 KFY02002.1 - 3.2e-31 107.7 0.0 6.5e-31 106.7 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 KFY02002.1 - 1.3e-18 67.0 0.0 2.9e-18 65.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFY02002.1 - 7.8e-10 38.2 0.1 1.4e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.18 KFY02002.1 - 0.0015 18.3 2.1 0.16 11.7 0.2 2.6 3 0 0 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 KFY02002.1 - 0.0021 17.5 0.3 0.87 8.9 0.0 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 KFY02002.1 - 0.003 17.1 0.1 0.8 9.2 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein VirB8 PF04335.8 KFY02002.1 - 0.004 16.7 0.0 0.0069 15.9 0.0 1.3 1 0 0 1 1 1 1 VirB8 protein KTI12 PF08433.5 KFY02002.1 - 0.089 11.9 0.0 0.22 10.6 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.22 KFY02002.1 - 0.1 12.8 0.1 0.59 10.4 0.0 2.0 2 0 0 2 2 2 0 ABC transporter DUF4066 PF13278.1 KFY02010.1 - 1.1e-23 83.3 0.0 1.3e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KFY02010.1 - 2.3e-08 33.6 0.0 2.9e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 KFY02010.1 - 0.034 13.5 0.0 0.04 13.3 0.0 1.2 1 1 0 1 1 1 0 Glutamine amidotransferase class-I DUF883 PF05957.8 KFY02010.1 - 0.17 12.2 0.4 0.28 11.5 0.3 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Pkinase PF00069.20 KFY02011.1 - 5.1e-26 91.3 0.0 1.9e-24 86.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY02011.1 - 3.6e-09 36.0 0.0 5.7e-08 32.1 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Pyr_redox_3 PF13738.1 KFY02012.1 - 9.4e-17 61.7 0.2 2.6e-16 60.3 0.0 1.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFY02012.1 - 2.9e-12 45.5 0.1 1e-10 40.5 0.0 2.4 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KFY02012.1 - 3.3e-08 32.8 0.0 2.8e-06 26.4 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KFY02012.1 - 6.1e-08 32.7 0.0 0.00039 20.3 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFY02012.1 - 8.3e-05 22.5 0.0 0.04 13.9 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFY02012.1 - 0.0018 18.6 0.1 0.12 12.7 0.0 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFY02012.1 - 0.015 14.2 0.0 0.37 9.6 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 KFY02012.1 - 0.02 15.1 0.0 1.9 8.8 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.13 KFY02012.1 - 0.025 14.5 2.7 22 5.1 0.1 4.4 5 0 0 5 5 5 0 TrkA-N domain DAO PF01266.19 KFY02012.1 - 0.12 11.2 0.6 31 3.3 0.1 3.3 2 1 0 3 3 3 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 KFY02012.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.11 KFY02013.1 - 3e-13 49.2 34.2 4.8e-13 48.5 23.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KFY02013.1 - 2.2e-10 40.2 5.0 2.2e-10 40.2 3.5 2.7 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 SSF PF00474.12 KFY02032.1 - 5.4e-22 77.9 34.8 8.4e-22 77.3 24.1 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family zf-trcl PF13451.1 KFY02033.1 - 0.87 9.2 5.7 0.22 11.1 0.9 2.1 2 0 0 2 2 2 0 Probable zinc-binding domain Ribosomal_L37e PF01907.14 KFY02033.1 - 1.2 9.0 6.7 12 5.8 2.8 2.6 2 1 0 2 2 2 0 Ribosomal protein L37e DM PF00751.13 KFY02033.1 - 7.7 6.1 9.2 8.9 5.9 4.2 2.4 2 1 0 2 2 2 0 DM DNA binding domain GrpE PF01025.14 KFY02034.1 - 0.022 14.3 1.7 0.048 13.2 1.2 1.6 1 1 0 1 1 1 0 GrpE IncA PF04156.9 KFY02034.1 - 6.7 6.2 7.9 1e+02 2.3 5.5 2.3 1 1 0 1 1 1 0 IncA protein CinA PF02464.12 KFY02035.1 - 3.4e-33 114.3 0.3 4.4e-33 113.9 0.2 1.1 1 0 0 1 1 1 1 Competence-damaged protein DUF155 PF02582.9 KFY02036.1 - 1.3e-58 197.7 0.1 1.9e-58 197.2 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 PIG-X PF08320.7 KFY02037.1 - 5.4e-47 159.7 0.1 1.1e-46 158.7 0.0 1.5 1 0 0 1 1 1 1 PIG-X / PBN1 MULE PF10551.4 KFY02041.1 - 0.012 15.7 0.1 0.019 15.1 0.1 1.6 1 1 0 1 1 1 0 MULE transposase domain Alpha-amylase PF00128.19 KFY02051.1 - 4e-66 223.5 0.0 5.2e-66 223.1 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KFY02051.1 - 2.4e-18 65.9 0.6 8.4e-18 64.2 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Glyco_hydro_15 PF00723.16 KFY02052.1 - 3.8e-100 335.5 0.3 4.3e-100 335.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 GMC_oxred_N PF00732.14 KFY02053.1 - 6.6e-25 87.8 0.1 7.1e-24 84.4 0.1 2.2 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFY02053.1 - 1.1e-19 71.1 0.0 2.4e-19 70.0 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KFY02053.1 - 6.6e-09 35.1 0.0 1.3e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFY02053.1 - 8.7e-06 24.8 0.6 0.00012 21.0 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFY02053.1 - 0.0005 20.1 0.2 0.075 13.0 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFY02053.1 - 0.0034 17.3 0.0 0.0092 15.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFY02053.1 - 0.0047 17.3 0.2 0.21 12.0 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFY02053.1 - 0.005 15.3 0.1 0.0078 14.7 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KFY02053.1 - 0.007 16.2 0.1 0.025 14.4 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KFY02053.1 - 0.092 11.7 0.8 0.15 11.0 0.2 1.6 2 0 0 2 2 2 0 FAD binding domain Chitin_bind_3 PF03067.10 KFY02054.1 - 7.3e-09 36.1 0.0 1.8e-05 25.0 0.0 2.3 1 1 0 2 2 2 2 Chitin binding domain Omega-toxin PF06357.6 KFY02054.1 - 2.5 7.7 7.9 1.1 8.8 2.9 2.2 2 0 0 2 2 2 0 Omega-atracotoxin adh_short PF00106.20 KFY02055.1 - 4.1e-15 56.0 0.0 6.6e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFY02055.1 - 7.6e-08 32.2 0.0 1.1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFY02055.1 - 0.0011 18.4 0.0 0.0016 17.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KFY02055.1 - 0.076 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase HeLo PF14479.1 KFY02056.1 - 1.4e-13 51.0 0.1 1.5e-13 51.0 0.1 1.0 1 0 0 1 1 1 1 Prion-inhibition and propagation Cupin_2 PF07883.6 KFY02057.1 - 0.008 15.6 4.4 0.61 9.6 0.1 3.4 3 1 0 3 3 3 2 Cupin domain PMI_typeI PF01238.16 KFY02057.1 - 0.0089 15.0 0.0 0.018 13.9 0.0 1.5 1 0 0 1 1 1 1 Phosphomannose isomerase type I JmjC PF02373.17 KFY02057.1 - 0.15 12.2 0.3 0.28 11.4 0.2 1.5 1 1 0 1 1 1 0 JmjC domain, hydroxylase Glyco_hydro_2 PF00703.16 KFY02058.1 - 7.3e-09 36.0 0.0 2e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KFY02058.1 - 9.4e-07 28.5 0.1 2.8e-06 27.0 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KFY02058.1 - 0.0026 16.7 0.1 0.0053 15.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Sugar_tr PF00083.19 KFY02059.1 - 1e-84 284.7 25.7 1.1e-84 284.5 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY02059.1 - 3.4e-22 78.6 21.1 3.4e-22 78.6 14.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 KFY02060.1 - 7.9e-08 32.0 12.2 1.5e-07 31.2 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFY02060.1 - 4.7e-07 28.7 5.1 2.3e-06 26.4 3.5 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Apc3 PF12895.2 KFY02060.1 - 0.042 13.9 0.7 11 6.2 0.2 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Metallophos PF00149.23 KFY02061.1 - 3.5e-05 23.2 0.7 0.0001 21.7 0.5 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KFY02061.1 - 0.00023 21.0 0.0 0.00054 19.8 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Pyridox_oxidase PF01243.15 KFY02062.1 - 0.00078 19.4 0.0 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase F-box-like PF12937.2 KFY02065.1 - 6.7e-09 35.3 4.8 0.0037 16.9 0.0 4.3 5 0 0 5 5 5 2 F-box-like F-box PF00646.28 KFY02065.1 - 0.00012 21.5 0.1 7.3 6.3 0.0 3.8 3 0 0 3 3 3 3 F-box domain DUF2089 PF09862.4 KFY02065.1 - 0.093 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2089) TPR_10 PF13374.1 KFY02066.1 - 7.4e-97 314.8 17.3 1.4e-08 34.4 0.0 12.1 12 0 0 12 12 12 11 Tetratricopeptide repeat TPR_12 PF13424.1 KFY02066.1 - 7.4e-85 278.9 32.5 4.9e-15 55.2 0.3 10.2 1 1 10 11 11 11 10 Tetratricopeptide repeat TPR_11 PF13414.1 KFY02066.1 - 1.8e-13 49.8 5.1 0.002 17.7 0.0 6.8 3 2 7 10 10 10 7 TPR repeat TPR_4 PF07721.9 KFY02066.1 - 2.7e-13 48.9 0.0 5.2 7.7 0.0 9.2 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFY02066.1 - 9.6e-12 45.2 0.0 0.16 12.6 0.0 7.4 2 1 8 10 10 10 4 Tetratricopeptide repeat TPR_17 PF13431.1 KFY02066.1 - 1.6e-10 40.3 6.2 0.56 10.5 0.0 10.9 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFY02066.1 - 1.6e-10 40.0 0.8 6.7 6.5 0.0 8.8 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFY02066.1 - 8.4e-10 37.8 2.4 3.4 7.7 0.0 8.6 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFY02066.1 - 1.1e-08 35.2 0.3 0.0011 19.2 0.0 4.9 2 2 4 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFY02066.1 - 0.0074 16.0 17.1 2.3 8.2 0.0 8.4 10 0 0 10 10 10 1 Tetratricopeptide repeat TSC22 PF01166.13 KFY02067.1 - 0.0045 16.9 0.2 11 6.0 0.0 3.7 3 0 0 3 3 3 0 TSC-22/dip/bun family Sporozoite_P67 PF05642.6 KFY02067.1 - 0.0048 14.8 0.0 0.0095 13.8 0.0 1.4 2 0 0 2 2 2 1 Sporozoite P67 surface antigen Filament PF00038.16 KFY02067.1 - 0.0077 15.7 12.0 0.009 15.5 0.8 3.0 2 1 0 3 3 3 1 Intermediate filament protein DUF4515 PF14988.1 KFY02067.1 - 0.0081 15.8 0.2 0.0081 15.8 0.1 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4515) TMF_TATA_bd PF12325.3 KFY02067.1 - 0.014 15.1 12.4 0.035 13.8 0.3 4.2 3 1 1 4 4 4 0 TATA element modulatory factor 1 TATA binding AAA_13 PF13166.1 KFY02067.1 - 0.025 13.0 2.3 0.91 7.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain DUF148 PF02520.12 KFY02067.1 - 0.076 12.8 0.1 2.4 7.9 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF148 DUF904 PF06005.7 KFY02067.1 - 0.13 12.5 6.6 6.8 7.0 0.5 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF904) ApoO PF09769.4 KFY02067.1 - 0.15 11.7 0.6 0.55 9.9 0.0 2.2 2 0 0 2 2 2 0 Apolipoprotein O Seryl_tRNA_N PF02403.17 KFY02067.1 - 0.17 11.8 4.3 6.5 6.8 0.1 3.4 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain FH2 PF02181.18 KFY02067.1 - 0.21 10.4 3.5 11 4.7 0.0 3.1 2 1 1 3 3 3 0 Formin Homology 2 Domain WEMBL PF05701.6 KFY02067.1 - 0.44 8.9 5.6 13 4.0 0.2 3.0 3 0 0 3 3 3 0 Weak chloroplast movement under blue light ADIP PF11559.3 KFY02067.1 - 0.66 9.8 10.5 2.1 8.2 1.0 3.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF2383 PF09537.5 KFY02067.1 - 1.2 9.4 3.8 18 5.6 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF2383) PhoU PF01895.14 KFY02067.1 - 1.3 9.5 5.5 2.5 8.6 0.2 3.3 3 1 0 3 3 3 0 PhoU domain Lebercilin PF15619.1 KFY02067.1 - 1.5 8.2 9.7 0.1 12.0 0.6 3.0 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease IncA PF04156.9 KFY02067.1 - 3.1 7.3 11.8 11 5.5 1.3 3.3 2 2 1 3 3 3 0 IncA protein DUF3552 PF12072.3 KFY02067.1 - 7.4 5.7 12.8 0.12 11.6 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3552) Pkinase PF00069.20 KFY02069.1 - 0.00043 19.5 0.0 0.00084 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain UPF0060 PF02694.10 KFY02071.1 - 0.00086 19.3 2.1 0.0015 18.5 1.5 1.3 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family Arteri_Gl PF00951.13 KFY02071.1 - 0.79 9.2 6.3 1.2 8.6 4.4 1.2 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein EST1_DNA_bind PF10373.4 KFY02073.1 - 5e-08 32.5 0.2 3.2e-07 29.8 0.0 2.5 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain Cytadhesin_P30 PF07271.6 KFY02074.1 - 1.8 7.7 8.5 6.3 5.9 5.9 1.8 1 1 0 1 1 1 0 Cytadhesin P30/P32 Prp18 PF02840.10 KFY02100.1 - 1.4e-39 135.2 0.0 1.4e-39 135.2 0.0 2.2 2 1 0 2 2 2 1 Prp18 domain WW PF00397.21 KFY02100.1 - 1.8e-16 59.6 8.8 6e-08 32.4 2.6 2.8 2 0 0 2 2 2 2 WW domain CAF-1_p150 PF11600.3 KFY02100.1 - 0.31 10.3 36.1 0.58 9.5 25.1 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal eIF-3c_N PF05470.7 KFY02100.1 - 0.4 8.6 15.7 0.64 8.0 10.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC27 PF09507.5 KFY02100.1 - 2 7.5 29.7 3.5 6.7 20.6 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ycf1 PF05758.7 KFY02100.1 - 4.3 4.9 9.9 5.3 4.6 6.9 1.2 1 0 0 1 1 1 0 Ycf1 DUF4192 PF13830.1 KFY02100.1 - 8.3 5.9 11.5 13 5.3 7.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Kri1_C PF12936.2 KFY02101.1 - 8.1e-30 102.6 1.0 8.1e-30 102.6 0.7 3.3 4 0 0 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.7 KFY02101.1 - 5.4e-23 81.1 16.4 5.4e-23 81.1 11.3 5.4 5 1 0 5 5 5 1 KRI1-like family Ras PF00071.17 KFY02102.1 - 8.1e-57 191.1 0.0 9.9e-57 190.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFY02102.1 - 6.9e-19 68.5 0.0 9.8e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFY02102.1 - 1.1e-13 50.8 0.0 1.4e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFY02102.1 - 9.8e-07 28.1 0.0 1.2e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KFY02102.1 - 1e-05 25.0 0.0 2.4e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFY02102.1 - 0.00062 19.7 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 KFY02102.1 - 0.0064 16.4 0.0 0.015 15.2 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFY02102.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain DNA_pol_phi PF04931.8 KFY02102.1 - 0.8 7.4 5.7 1.1 6.9 3.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Scs3p PF10261.4 KFY02103.1 - 1.4e-62 210.8 1.2 1.4e-62 210.8 0.8 1.8 2 0 0 2 2 2 1 Inositol phospholipid synthesis and fat-storage-inducing TM FA_desaturase PF00487.19 KFY02103.1 - 5 6.4 10.6 1.8 7.9 1.4 2.3 2 0 0 2 2 2 0 Fatty acid desaturase EBP PF05241.7 KFY02105.1 - 0.00058 18.9 0.1 0.00058 18.9 0.1 1.9 2 0 0 2 2 2 1 Emopamil binding protein WD40 PF00400.27 KFY02106.1 - 1.1e-55 183.5 27.1 4.2e-12 45.4 2.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KFY02106.1 - 1e-41 142.3 0.7 1.6e-41 141.7 0.5 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nucleoporin_N PF08801.6 KFY02106.1 - 3.5e-06 26.0 0.2 0.3 9.7 0.0 3.7 2 2 2 4 4 4 2 Nup133 N terminal like LisH PF08513.6 KFY02106.1 - 7.1e-05 22.4 0.0 0.00016 21.3 0.0 1.6 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 KFY02106.1 - 0.00037 18.7 6.8 0.015 13.4 0.4 3.3 1 1 0 3 3 3 2 Nucleoporin Nup120/160 Med11 PF10280.4 KFY02107.1 - 7.2e-31 106.6 0.1 9e-31 106.3 0.1 1.1 1 0 0 1 1 1 1 Mediator complex protein Vps5 PF09325.5 KFY02108.1 - 6.9e-85 284.0 2.5 1.2e-84 283.2 1.7 1.4 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KFY02108.1 - 1.1e-23 83.2 0.0 2.2e-23 82.1 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_2 PF10455.4 KFY02108.1 - 0.0079 15.1 0.5 0.013 14.4 0.4 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KFY02108.1 - 0.023 14.2 3.4 0.036 13.5 2.4 1.3 1 0 0 1 1 1 0 BAR domain Ribosomal_L31 PF01197.13 KFY02109.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L31 Flavin_Reduct PF01613.13 KFY02110.1 - 1.2e-25 90.1 0.0 1.7e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain HSP90 PF00183.13 KFY02111.1 - 1.3e-251 835.6 31.5 1.5e-251 835.4 21.8 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 KFY02111.1 - 7.1e-11 41.9 0.2 7.1e-11 41.9 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KFY02111.1 - 8.6e-11 41.5 0.1 1.6e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.8 KFY02111.1 - 0.05 13.9 0.4 0.05 13.9 0.3 3.5 4 1 0 4 4 4 0 Protein of unknown function (DUF1676) SSrecog PF03531.9 KFY02112.1 - 9.9e-75 250.6 1.7 1.3e-73 246.9 1.2 2.2 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KFY02112.1 - 9.4e-25 86.4 0.0 9e-24 83.2 0.0 2.4 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF2201_N PF13203.1 KFY02112.1 - 0.05 12.7 0.1 0.05 12.7 0.0 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain Pkinase PF00069.20 KFY02113.1 - 8.4e-77 257.8 0.0 9.5e-77 257.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY02113.1 - 1.1e-35 122.9 0.0 1.4e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFY02113.1 - 0.012 14.6 0.0 0.028 13.4 0.0 1.6 1 1 0 1 1 1 0 Kinase-like APH PF01636.18 KFY02113.1 - 0.083 12.6 0.1 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sporozoite_P67 PF05642.6 KFY02131.1 - 2.8 5.6 6.2 2.9 5.6 4.3 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Anophelin PF10731.4 KFY02132.1 - 8.2 6.6 7.9 21 5.3 5.5 1.7 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito Actin PF00022.14 KFY02140.1 - 5.4e-128 426.7 0.0 6.2e-128 426.5 0.0 1.0 1 0 0 1 1 1 1 Actin Orbi_VP6 PF01516.11 KFY02141.1 - 1.4 7.9 6.1 1.8 7.5 4.2 1.1 1 0 0 1 1 1 0 Orbivirus helicase VP6 Pkinase PF00069.20 KFY02142.1 - 6.1e-75 251.7 0.0 8.8e-75 251.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY02142.1 - 7.1e-39 133.4 0.0 1e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 KFY02142.1 - 1.9e-15 56.7 0.2 7.6e-15 54.8 0.1 2.1 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 KFY02142.1 - 9.8e-07 28.0 0.0 1.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KFY02142.1 - 5.9e-05 22.5 0.5 0.0001 21.7 0.3 1.3 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 KFY02142.1 - 0.0021 16.7 0.1 0.0032 16.1 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.9 KFY02142.1 - 0.016 14.2 0.1 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFY02142.1 - 0.063 13.0 0.6 0.5 10.0 0.1 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family CytochromB561_N PF09786.4 KFY02142.1 - 0.17 10.3 1.9 0.26 9.7 1.3 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal NDUFA12 PF05071.11 KFY02143.1 - 1.1e-11 45.0 0.1 2.7e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Hemopexin PF00045.14 KFY02143.1 - 0.1 12.3 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Hemopexin HAD_2 PF13419.1 KFY02158.1 - 2.5e-33 115.7 0.1 3e-33 115.5 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFY02158.1 - 4.1e-06 27.3 0.0 2.8e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFY02158.1 - 1.4e-05 24.7 0.0 2.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like ABC_tran PF00005.22 KFY02178.1 - 3.6e-34 118.0 0.0 9.5e-34 116.6 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KFY02178.1 - 1.5e-26 93.4 7.8 2e-26 93.0 5.4 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 KFY02178.1 - 1.2e-07 31.1 3.9 1.6e-06 27.5 2.7 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFY02178.1 - 2.2e-05 24.5 0.2 0.0053 16.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFY02178.1 - 0.00029 20.8 0.2 0.00082 19.4 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 KFY02178.1 - 0.0016 18.3 0.3 0.015 15.1 0.2 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 KFY02178.1 - 0.0032 16.9 0.1 0.0071 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 KFY02178.1 - 0.004 16.3 0.0 0.0086 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KFY02178.1 - 0.005 16.9 0.2 0.043 13.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFY02178.1 - 0.09 12.1 0.1 0.63 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Pyr_redox_2 PF07992.9 KFY02179.1 - 5.7e-28 98.1 0.0 9.7e-27 94.1 0.0 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFY02179.1 - 1.2e-13 51.2 0.0 1.5e-11 44.5 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFY02179.1 - 8.2e-05 22.7 0.5 0.11 12.4 0.2 4.0 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DUF260 PF03195.9 KFY02179.1 - 0.16 12.2 0.1 8.4 6.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function DUF260 HI0933_like PF03486.9 KFY02179.1 - 1.2 7.5 4.8 0.58 8.5 0.1 2.4 2 1 1 3 3 3 0 HI0933-like protein Acetyltransf_1 PF00583.19 KFY02180.1 - 1.5e-08 34.5 0.0 2.3e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFY02180.1 - 1.1e-06 28.7 0.0 2.1e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFY02180.1 - 1.2e-06 28.6 0.0 2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFY02180.1 - 2e-05 24.2 0.0 3.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KFY02180.1 - 0.00034 20.4 0.0 0.1 12.4 0.0 2.5 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFY02180.1 - 0.0042 16.9 0.0 0.0065 16.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase End_beta_barrel PF12195.3 KFY02181.1 - 0.043 13.5 0.1 0.16 11.7 0.0 2.0 1 0 0 1 1 1 0 Beta barrel domain of bacteriophage endosialidase DUF4620 PF15399.1 KFY02181.1 - 6.4 6.9 18.5 0.12 12.4 4.0 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4620) Glyco_transf_54 PF04666.8 KFY02182.1 - 3.2e-11 42.5 0.2 2.8e-10 39.4 0.2 2.0 1 1 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region CAF-1_p150 PF11600.3 KFY02182.1 - 0.0013 18.1 9.7 0.0028 17.0 6.7 1.5 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal LANC_like PF05147.8 KFY02185.1 - 1.2e-21 76.6 0.0 4e-21 74.9 0.0 1.8 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein Abhydrolase_6 PF12697.2 KFY02186.1 - 2.2e-23 83.3 0.8 2.6e-23 83.1 0.5 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFY02186.1 - 1.3e-09 37.9 0.0 1.6e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3328 PF11807.3 KFY02194.1 - 5e-49 166.9 0.0 6.5e-49 166.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4143 PF13635.1 KFY02195.1 - 0.023 14.8 1.8 3.6 7.8 1.3 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4143) gpW PF02831.10 KFY02195.1 - 1.1 8.8 4.5 23 4.6 3.1 2.7 1 1 0 1 1 1 0 gpW AFG1_ATPase PF03969.11 KFY02197.1 - 4.1e-97 325.2 0.0 2.1e-91 306.4 0.0 2.4 2 0 0 2 2 2 2 AFG1-like ATPase Hist_deacetyl PF00850.14 KFY02197.1 - 6.4e-61 206.3 0.1 1.3e-60 205.3 0.1 1.5 1 0 0 1 1 1 1 Histone deacetylase domain AAA_16 PF13191.1 KFY02197.1 - 0.00054 19.9 0.7 0.17 11.8 0.0 3.1 2 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 KFY02197.1 - 0.058 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KFY02197.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.13 KFY02197.1 - 0.17 11.4 0.3 7.5 6.1 0.1 2.4 2 1 0 2 2 2 0 Bacterial dnaA protein DUF663 PF04950.7 KFY02198.1 - 3.8e-87 292.0 0.0 8e-87 290.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KFY02198.1 - 5.3e-28 96.3 0.0 1.6e-27 94.8 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 KFY02198.1 - 7.4e-06 25.5 0.0 0.0018 17.7 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 KFY02198.1 - 7.6e-06 26.0 0.0 2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFY02198.1 - 1.2e-05 25.4 0.0 2.9e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFY02198.1 - 5.1e-05 24.0 0.0 5.1e-05 24.0 0.0 4.4 3 1 1 4 4 2 1 AAA domain NACHT PF05729.7 KFY02198.1 - 6.9e-05 22.5 0.0 0.00014 21.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.18 KFY02198.1 - 0.00031 20.6 0.0 0.00079 19.3 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFY02198.1 - 0.00036 21.0 0.0 0.0016 18.8 0.0 2.2 1 0 0 1 1 1 1 Miro-like protein AAA_33 PF13671.1 KFY02198.1 - 0.00037 20.3 0.0 0.0011 18.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KFY02198.1 - 0.00041 19.8 0.0 0.0012 18.3 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 KFY02198.1 - 0.00042 20.6 0.4 0.0015 18.7 0.0 2.2 2 0 0 2 2 1 1 ABC transporter AAA PF00004.24 KFY02198.1 - 0.00049 20.2 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KFY02198.1 - 0.00078 19.1 0.5 0.0041 16.8 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_10 PF12846.2 KFY02198.1 - 0.001 18.5 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain AAA_25 PF13481.1 KFY02198.1 - 0.0013 18.1 0.0 0.0046 16.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain MobB PF03205.9 KFY02198.1 - 0.0018 17.9 0.1 0.0064 16.1 0.0 2.0 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KFY02198.1 - 0.0018 18.5 0.0 0.0018 18.5 0.0 3.7 3 1 0 3 3 2 1 AAA domain AAA_14 PF13173.1 KFY02198.1 - 0.0047 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KFY02198.1 - 0.0067 16.0 0.1 0.019 14.5 0.1 1.8 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KFY02198.1 - 0.011 14.5 0.0 0.037 12.8 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.1 KFY02198.1 - 0.013 15.4 3.6 0.018 15.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 KFY02198.1 - 0.013 15.1 0.1 0.032 13.9 0.1 1.7 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.17 KFY02198.1 - 0.016 15.3 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF258 PF03193.11 KFY02198.1 - 0.019 14.1 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 cobW PF02492.14 KFY02198.1 - 0.021 14.2 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 KFY02198.1 - 0.054 13.2 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 KFY02198.1 - 0.11 12.0 0.0 0.38 10.2 0.0 2.0 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 KFY02198.1 - 0.12 11.8 2.1 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_21 PF13304.1 KFY02198.1 - 0.21 11.4 4.8 0.79 9.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 KFY02198.1 - 2.2 7.8 5.9 3.7 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain Ribosomal_L13e PF01294.13 KFY02203.1 - 3.7e-64 215.4 6.6 5e-64 215.0 4.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Hormone_2 PF00123.15 KFY02203.1 - 0.15 11.8 1.6 0.32 10.8 1.1 1.5 1 0 0 1 1 1 0 Peptide hormone Aha1_N PF09229.6 KFY02204.1 - 0.0043 16.8 0.0 0.89 9.3 0.0 2.1 2 0 0 2 2 2 2 Activator of Hsp90 ATPase, N-terminal Birna_VP5 PF03042.9 KFY02204.1 - 0.21 11.1 1.5 9.3 5.7 0.1 2.2 2 0 0 2 2 2 0 Birnavirus VP5 protein DUF702 PF05142.7 KFY02204.1 - 0.65 10.1 8.5 17 5.5 0.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF702) GCC2_GCC3 PF07699.8 KFY02204.1 - 6.6 6.4 21.4 7.3 6.2 0.9 3.4 3 0 0 3 3 3 0 GCC2 and GCC3 Amidoligase_2 PF12224.3 KFY02205.1 - 2.9e-21 76.2 0.0 3.8e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme Abhydrolase_4 PF08386.5 KFY02207.1 - 5.2e-20 71.2 0.0 1e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KFY02207.1 - 2.9e-15 56.4 0.0 6.4e-15 55.3 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFY02207.1 - 1.4e-05 25.0 0.0 0.00027 20.9 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FA_hydroxylase PF04116.8 KFY02208.1 - 6.9e-15 55.4 14.1 6.9e-15 55.4 9.7 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Hexapep PF00132.19 KFY02209.1 - 7.7e-18 63.1 17.2 2.4e-12 45.7 3.2 4.1 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KFY02209.1 - 3.8e-16 58.3 8.3 1.4e-09 37.3 3.4 3.6 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 KFY02209.1 - 4.5e-06 26.5 0.1 7.6e-06 25.8 0.1 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Glyco_hydro_1 PF00232.13 KFY02210.1 - 2.9e-103 345.5 0.0 3.4e-103 345.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 TruD PF01142.13 KFY02211.1 - 4.3e-53 180.3 6.2 2.4e-50 171.2 0.0 4.4 4 0 0 4 4 4 2 tRNA pseudouridine synthase D (TruD) SAD_SRA PF02182.12 KFY02211.1 - 0.023 14.0 0.0 0.054 12.7 0.0 1.6 1 0 0 1 1 1 0 SAD/SRA domain DUF4146 PF13652.1 KFY02211.1 - 0.054 13.3 0.0 0.21 11.4 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4146) Ycf1 PF05758.7 KFY02211.1 - 0.75 7.4 8.7 1.4 6.4 0.3 2.2 2 0 0 2 2 2 0 Ycf1 HsbA PF12296.3 KFY02213.1 - 0.0012 18.6 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A adh_short PF00106.20 KFY02214.1 - 2.3e-17 63.4 0.4 2e-16 60.3 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFY02214.1 - 5.6e-06 26.1 0.0 2.4e-05 24.0 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KFY02214.1 - 0.00021 20.8 0.0 0.00029 20.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KFY02214.1 - 0.0022 17.8 0.0 0.0032 17.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Zn_clus PF00172.13 KFY02215.1 - 3.8e-07 29.8 10.0 3.8e-07 29.8 6.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COG7 PF10191.4 KFY02215.1 - 0.065 11.1 0.7 0.092 10.6 0.5 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) adh_short PF00106.20 KFY02217.1 - 5.4e-20 71.9 0.1 3.4e-19 69.3 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFY02217.1 - 2.3e-09 37.3 0.0 5.5e-07 29.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFY02217.1 - 4.1e-09 36.3 0.1 6e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFY02217.1 - 0.0024 17.9 0.4 0.041 13.9 0.3 2.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFY02217.1 - 0.007 15.8 0.0 0.016 14.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFY02217.1 - 0.13 11.1 0.0 0.44 9.4 0.0 1.8 1 1 0 1 1 1 0 Male sterility protein DUF3176 PF11374.3 KFY02218.1 - 0.038 13.8 0.5 0.088 12.6 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) HTH_psq PF05225.11 KFY02219.1 - 6.8e-08 31.9 0.1 1.9e-07 30.5 0.1 1.8 1 0 0 1 1 1 1 helix-turn-helix, Psq domain Selenoprotein_S PF06936.6 KFY02219.1 - 0.016 14.7 0.1 0.023 14.2 0.1 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) ADH_N PF08240.7 KFY02220.1 - 3.5e-22 78.2 5.3 6.4e-22 77.3 3.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFY02220.1 - 2.7e-16 59.2 0.0 4.9e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KFY02220.1 - 0.00016 20.8 0.1 0.00027 20.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KFY02220.1 - 0.035 13.7 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KFY02220.1 - 0.047 13.5 0.2 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.16 KFY02220.1 - 0.051 13.1 0.3 0.1 12.1 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.16 KFY02220.1 - 0.068 12.9 1.5 0.13 12.0 1.0 1.5 1 0 0 1 1 1 0 ThiF family PhzC-PhzF PF02567.11 KFY02221.1 - 9e-41 139.9 0.3 2.3e-40 138.6 0.2 1.6 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Amidohydro_3 PF07969.6 KFY02222.1 - 1.8e-56 192.1 0.6 2.1e-56 191.9 0.4 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KFY02222.1 - 9.7e-09 34.9 0.8 2.7e-08 33.5 0.3 2.0 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 KFY02222.1 - 5.2e-06 26.3 1.3 0.0028 17.3 0.9 3.3 1 1 0 1 1 1 1 Amidohydrolase family HlyIII PF03006.15 KFY02224.1 - 1.9e-53 181.1 19.5 2.3e-53 180.8 13.5 1.1 1 0 0 1 1 1 1 Haemolysin-III related Isochorismatase PF00857.15 KFY02225.1 - 2.8e-18 66.4 0.0 4.2e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Cytochrom_B561 PF03188.11 KFY02225.1 - 1.5e-07 31.3 10.4 2.4e-07 30.6 7.2 1.3 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 KFY02225.1 - 2.9e-07 29.9 3.0 7.2e-07 28.7 2.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) DUF2306 PF10067.4 KFY02225.1 - 0.82 9.8 13.1 0.5 10.5 1.2 3.0 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) DUF3487 PF11990.3 KFY02225.1 - 1.9 7.8 5.3 0.93 8.9 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3487) DUF373 PF04123.8 KFY02225.1 - 3.5 6.5 6.2 18 4.2 2.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Fungal_trans PF04082.13 KFY02226.1 - 2e-08 33.4 0.2 4.7e-08 32.2 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Prion PF00377.13 KFY02226.1 - 0.031 13.9 0.1 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Prion/Doppel alpha-helical domain DUF4441 PF14536.1 KFY02226.1 - 0.084 12.8 0.9 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) DUF2263 PF10021.4 KFY02227.1 - 3.5e-24 85.4 0.0 5.7e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.16 KFY02227.1 - 0.0061 16.4 0.0 0.014 15.3 0.0 1.6 2 0 0 2 2 2 1 Macro domain Zip PF02535.17 KFY02229.1 - 3.2e-48 164.3 2.9 3.7e-48 164.1 2.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF3505 PF12013.3 KFY02230.1 - 4.2e-08 33.3 0.1 9.9e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) Fungal_trans_2 PF11951.3 KFY02230.1 - 1.6e-05 23.6 0.2 2.6e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.17 KFY02231.1 - 1.3e-69 234.9 0.0 1.6e-69 234.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_5 PF12695.2 KFY02232.1 - 1.6e-12 47.4 0.0 2.5e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFY02232.1 - 6.4e-09 36.0 0.0 8.6e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KFY02232.1 - 4.3e-05 22.1 0.1 0.00027 19.5 0.1 2.1 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 KFY02232.1 - 4.4e-05 22.8 0.0 0.00021 20.5 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF1100 PF06500.6 KFY02232.1 - 0.00011 20.9 0.0 0.00017 20.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.13 KFY02232.1 - 0.00019 20.9 0.0 0.00034 20.1 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 KFY02232.1 - 0.00085 19.0 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Anth_synt_I_N PF04715.8 KFY02234.1 - 4.8e-26 91.4 0.0 1.1e-25 90.2 0.0 1.6 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Chorismate_bind PF00425.13 KFY02234.1 - 0.0035 16.7 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 2 chorismate binding enzyme ATG16 PF08614.6 KFY02235.1 - 0.011 15.5 3.4 0.011 15.5 2.3 2.8 2 1 0 3 3 3 0 Autophagy protein 16 (ATG16) DinB PF05163.7 KFY02235.1 - 1.5 8.4 7.0 0.11 12.2 0.4 2.2 2 1 0 3 3 3 0 DinB family Sugar_tr PF00083.19 KFY02236.1 - 3.9e-86 289.4 31.5 4.7e-86 289.1 21.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY02236.1 - 3.7e-21 75.2 57.2 1.4e-20 73.2 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribul_P_3_epim PF00834.14 KFY02238.1 - 6.2e-62 208.2 0.0 5.6e-61 205.1 0.0 1.9 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 KFY02238.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Glyco_trans_4_2 PF13477.1 KFY02238.1 - 0.12 12.2 0.0 1.1 9.0 0.0 2.1 1 1 0 1 1 1 0 Glycosyl transferase 4-like Pkinase PF00069.20 KFY02240.1 - 3e-23 82.3 0.0 3.9e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY02240.1 - 7.9e-20 71.0 0.0 1.2e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFY02240.1 - 1.5e-05 24.1 0.0 2.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like TrkH PF02386.11 KFY02241.1 - 2.2e-90 302.7 5.6 8.6e-85 284.4 1.1 2.1 2 0 0 2 2 2 2 Cation transport protein HAD_2 PF13419.1 KFY02242.1 - 1.2e-19 71.2 0.0 1.6e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFY02242.1 - 3.1e-13 49.2 0.0 6.1e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KFY02242.1 - 1e-11 45.6 0.1 4.7e-09 36.9 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFY02242.1 - 2.8e-08 34.1 0.0 4.4e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KFY02242.1 - 2e-05 24.4 0.0 0.014 15.3 0.0 2.5 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 KFY02242.1 - 0.0019 17.8 0.0 2.1 7.9 0.0 2.9 3 0 0 3 3 3 1 Acid Phosphatase PGP_phosphatase PF09419.5 KFY02242.1 - 0.048 13.0 0.0 0.3 10.4 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Gp-FAR-1 PF05823.7 KFY02242.1 - 0.083 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) MTD PF01993.13 KFY02242.1 - 0.14 11.1 0.0 0.24 10.3 0.0 1.4 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase Hydrolase_3 PF08282.7 KFY02242.1 - 0.15 11.5 0.5 0.9 9.0 0.1 2.4 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase GPI-anchored PF10342.4 KFY02244.1 - 2.4e-05 24.7 0.0 8.2e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PAT1 PF09770.4 KFY02244.1 - 0.68 8.0 3.5 0.82 7.8 2.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 WSC PF01822.14 KFY02245.1 - 4.3e-15 55.4 7.1 1.1e-14 54.1 4.9 1.7 1 0 0 1 1 1 1 WSC domain Herpes_capsid PF06112.6 KFY02245.1 - 1.4 8.9 5.5 0.6 10.1 1.8 1.7 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein FAD_binding_4 PF01565.18 KFY02248.1 - 1.4e-29 102.3 0.7 2.5e-29 101.5 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFY02248.1 - 2e-10 40.4 0.0 4.1e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 KFY02249.1 - 4.6e-60 203.4 0.0 5.8e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_1 PF00175.16 KFY02250.1 - 3.4e-29 101.6 0.0 6.5e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KFY02250.1 - 1e-27 96.1 0.0 1.9e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 KFY02250.1 - 1.4e-23 82.4 0.0 3.1e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KFY02250.1 - 0.0015 18.4 0.0 0.018 14.9 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KFY02250.1 - 0.014 15.3 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain 3HCDH_N PF02737.13 KFY02251.1 - 8e-32 110.3 0.0 1.5e-31 109.4 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KFY02251.1 - 1.3e-17 64.0 0.0 6.5e-17 61.7 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 KFY02251.1 - 0.00021 21.0 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NHL PF01436.16 KFY02251.1 - 0.00036 20.3 0.0 0.16 11.9 0.0 4.1 5 0 0 5 5 5 1 NHL repeat NAD_binding_2 PF03446.10 KFY02251.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 KFY02251.1 - 0.041 13.3 0.0 0.24 10.8 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Lactonase PF10282.4 KFY02251.1 - 0.11 11.4 0.0 1.9 7.5 0.0 2.3 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller Antimicrobial19 PF08225.6 KFY02251.1 - 0.28 10.5 0.9 0.56 9.6 0.6 1.5 1 0 0 1 1 1 0 Pseudin antimicrobial peptide Ldl_recept_b PF00058.12 KFY02251.1 - 4.2 7.7 5.2 7.3 7.0 0.0 3.7 6 0 0 6 6 6 0 Low-density lipoprotein receptor repeat class B RhoGAP PF00620.22 KFY02252.1 - 6.8e-35 119.9 0.0 1.3e-34 118.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 KFY02252.1 - 5.2e-33 112.8 39.6 3e-12 46.3 5.0 5.0 5 0 0 5 5 5 4 LIM domain Desulfoferrod_N PF06397.7 KFY02252.1 - 6.1 6.3 6.5 0.34 10.3 0.1 2.3 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain UQ_con PF00179.21 KFY02253.1 - 4.2e-41 139.6 0.0 3.1e-29 101.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.17 KFY02253.1 - 0.002 17.9 0.0 0.14 12.0 0.0 2.5 1 1 1 2 2 2 1 RWD domain UEV PF05743.8 KFY02253.1 - 0.015 14.9 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 UEV domain Pkinase PF00069.20 KFY02254.1 - 1.5e-63 214.3 0.0 2.3e-39 135.1 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFY02254.1 - 4.7e-27 94.6 0.0 7.4e-20 71.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 KFY02254.1 - 2e-12 47.1 0.1 3.8e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 KFY02254.1 - 9.9e-08 31.2 0.0 5.7e-06 25.4 0.0 2.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KFY02254.1 - 6.4e-07 29.3 0.4 0.003 17.3 0.1 3.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 KFY02254.1 - 0.035 13.1 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.1 KFY02254.1 - 0.051 13.9 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 PAS domain Seadorna_VP7 PF07387.6 KFY02254.1 - 0.14 10.9 0.1 0.23 10.2 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Ank_5 PF13857.1 KFY02256.1 - 5.6e-24 83.6 0.9 6.8e-07 29.3 0.1 4.0 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 KFY02256.1 - 5.9e-22 77.8 0.0 4.7e-11 42.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFY02256.1 - 1.4e-20 72.0 0.1 9e-06 25.2 0.0 4.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.1 KFY02256.1 - 9.5e-20 68.7 0.0 4.4e-05 23.3 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KFY02256.1 - 3.2e-18 65.7 0.1 3.4e-07 30.5 0.0 3.3 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Pkinase PF00069.20 KFY02259.1 - 2.7e-71 239.7 0.0 3.6e-71 239.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY02259.1 - 1.4e-43 148.8 0.0 2e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFY02259.1 - 3.5e-12 45.8 0.0 8.1e-12 44.6 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KFY02259.1 - 0.0003 19.9 0.0 0.00054 19.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family OPA3 PF07047.7 KFY02260.1 - 3.5e-36 123.9 5.0 7.5e-36 122.8 3.5 1.5 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) AIF-MLS PF14962.1 KFY02260.1 - 0.12 11.9 8.8 1.3 8.6 3.4 2.2 2 0 0 2 2 2 0 Mitochondria Localisation Sequence Rootletin PF15035.1 KFY02260.1 - 0.69 9.8 13.6 3.2 7.6 9.4 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SBDS PF01172.13 KFY02264.1 - 1.3e-24 85.7 1.0 1.6e-24 85.4 0.7 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein RhoGEF PF00621.15 KFY02265.1 - 4.1e-24 85.4 0.0 6.1e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DEAD PF00270.24 KFY02266.1 - 1e-40 138.9 0.0 8.6e-40 135.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFY02266.1 - 3.2e-25 87.8 0.2 8.1e-25 86.4 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3334 PF11813.3 KFY02266.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) zf-CSL PF05207.8 KFY02268.1 - 2.9e-19 68.3 0.7 4.1e-19 67.8 0.5 1.2 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 KFY02268.1 - 6.6e-14 51.3 1.2 1.3e-13 50.5 0.9 1.5 1 1 0 1 1 1 1 DnaJ domain Mnd1 PF03962.10 KFY02269.1 - 5e-46 156.7 4.4 6e-46 156.4 3.0 1.0 1 0 0 1 1 1 1 Mnd1 family PEP-utilisers_N PF05524.8 KFY02269.1 - 0.0089 15.8 7.2 0.017 14.8 2.6 2.4 1 1 2 3 3 3 1 PEP-utilising enzyme, N-terminal TBPIP PF07106.8 KFY02269.1 - 0.0098 15.4 4.2 0.031 13.8 2.4 1.9 1 1 1 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Retrotrans_gag PF03732.12 KFY02269.1 - 0.19 11.7 0.9 0.48 10.5 0.0 2.1 3 0 0 3 3 3 0 Retrotransposon gag protein IncA PF04156.9 KFY02269.1 - 0.34 10.4 12.4 0.48 9.9 8.6 1.4 1 1 0 1 1 1 0 IncA protein CorA PF01544.13 KFY02269.1 - 0.83 8.6 5.9 1.2 8.0 4.1 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein V_ATPase_I PF01496.14 KFY02269.1 - 1.7 6.4 4.5 2.6 5.8 3.1 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Arrestin_N PF00339.24 KFY02270.1 - 4.1e-19 68.8 0.0 1.9e-17 63.4 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KFY02270.1 - 3.3e-11 43.4 0.0 1.1e-06 28.7 0.0 2.7 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain DLH PF01738.13 KFY02271.1 - 1.4e-33 116.0 0.0 1.7e-33 115.7 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFY02271.1 - 3.1e-07 30.2 0.0 4.1e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFY02271.1 - 0.0023 17.8 0.0 0.0046 16.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PDZ_2 PF13180.1 KFY02272.1 - 2.9e-07 30.2 0.0 4.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.9 KFY02272.1 - 8.1e-05 22.6 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.19 KFY02272.1 - 0.018 15.2 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) PAP2 PF01569.16 KFY02273.1 - 2.7e-15 56.1 0.2 5.1e-15 55.3 0.1 1.5 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 KFY02273.1 - 0.0067 16.1 0.0 0.074 12.7 0.0 2.1 2 0 0 2 2 2 1 Divergent PAP2 family Ras PF00071.17 KFY02274.1 - 3.5e-49 166.3 0.0 4.1e-49 166.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFY02274.1 - 3.4e-15 56.5 0.0 6.7e-15 55.6 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KFY02274.1 - 1.8e-10 40.3 0.0 2.4e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 KFY02274.1 - 0.00012 22.2 0.1 0.00056 20.0 0.1 2.0 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 KFY02274.1 - 0.0018 17.4 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 KFY02274.1 - 0.032 13.5 0.1 0.054 12.7 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 KFY02274.1 - 0.047 13.8 0.3 0.18 11.9 0.1 2.1 2 1 1 3 3 3 0 AAA domain G-alpha PF00503.15 KFY02274.1 - 0.062 11.9 2.1 1.1 7.8 0.1 2.6 2 1 1 3 3 3 0 G-protein alpha subunit AAA_33 PF13671.1 KFY02274.1 - 0.082 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain Telomere_reg-2 PF10193.4 KFY02276.1 - 1.4e-39 134.8 0.0 3.2e-39 133.7 0.0 1.7 1 0 0 1 1 1 1 Telomere length regulation protein ThiF PF00899.16 KFY02277.1 - 1.8e-37 128.1 0.1 5.9e-37 126.5 0.0 1.7 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 KFY02277.1 - 3.7e-28 97.1 0.0 7.2e-28 96.1 0.0 1.5 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 KFY02277.1 - 9.4e-25 85.9 0.5 2.7e-24 84.5 0.4 1.9 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KFY02277.1 - 7.6e-14 50.8 3.3 7.6e-14 50.8 2.3 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 KFY02277.1 - 0.00032 20.8 0.0 0.00067 19.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Ecm33 PF12454.3 KFY02277.1 - 0.091 12.6 0.7 0.22 11.4 0.5 1.6 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein TrkA_N PF02254.13 KFY02277.1 - 0.091 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain RNA_pol_A_bac PF01000.21 KFY02278.1 - 1.7e-25 89.3 0.0 3.6e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KFY02278.1 - 5.2e-16 57.5 0.0 7.5e-16 57.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.14 KFY02279.1 - 9.4e-134 444.5 0.0 1.2e-133 444.2 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit UQ_con PF00179.21 KFY02280.1 - 3.7e-22 78.2 0.3 6.8e-22 77.4 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KFY02280.1 - 0.0023 17.6 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KFY02280.1 - 0.015 15.1 0.1 0.044 13.6 0.0 1.8 2 0 0 2 2 2 0 RWD domain UEV PF05743.8 KFY02280.1 - 0.017 14.7 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain Pkinase PF00069.20 KFY02281.1 - 8.8e-72 241.3 0.0 1.2e-71 240.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY02281.1 - 7.5e-37 126.8 0.0 1.1e-36 126.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFY02281.1 - 1.2e-07 31.0 0.0 1.6e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KFY02281.1 - 0.00047 19.5 0.0 0.0052 16.1 0.0 2.3 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.9 KFY02281.1 - 0.014 14.4 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ENTH PF01417.15 KFY02287.1 - 2.4e-50 169.5 0.2 3.4e-50 169.1 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KFY02287.1 - 5.9e-06 25.1 0.0 9e-06 24.5 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 KFY02287.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 VHS domain UIM PF02809.15 KFY02287.1 - 0.095 12.3 0.3 0.095 12.3 0.2 3.5 3 1 1 4 4 4 0 Ubiquitin interaction motif DUF1510 PF07423.6 KFY02287.1 - 0.11 11.8 0.2 0.11 11.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) ERO1 PF04137.10 KFY02287.1 - 0.17 10.8 1.0 0.29 10.1 0.7 1.3 1 0 0 1 1 1 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) EF-hand_1 PF00036.27 KFY02288.1 - 2.4e-16 57.7 4.2 1.9e-08 32.9 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KFY02288.1 - 4.7e-15 55.4 0.8 2.6e-07 30.6 0.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFY02288.1 - 1.1e-14 52.9 3.7 3.7e-07 29.4 0.3 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KFY02288.1 - 1.5e-12 46.9 6.8 3.7e-05 23.2 0.2 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 KFY02288.1 - 1.2e-08 33.9 3.0 0.00017 20.7 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.2 KFY02288.1 - 0.00033 20.3 0.1 0.001 18.7 0.0 1.8 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KFY02288.1 - 0.015 15.2 0.0 0.5 10.3 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain Methyltransf_3 PF01596.12 KFY02288.1 - 0.087 11.8 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 O-methyltransferase Caleosin PF05042.8 KFY02288.1 - 0.099 12.1 0.0 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Caleosin related protein Nup96 PF12110.3 KFY02289.1 - 2.7e-92 308.9 0.8 4.1e-92 308.3 0.6 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 KFY02289.1 - 7.5e-44 148.9 0.0 1.2e-43 148.2 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 KFY02289.1 - 3.9e-15 56.0 85.5 1.5e-10 41.2 30.4 10.9 3 2 7 10 10 10 4 Nucleoporin FG repeat region AA_permease_2 PF13520.1 KFY02291.1 - 2.2e-56 191.2 28.0 2.6e-56 190.9 19.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFY02291.1 - 2.1e-23 82.4 31.5 3.9e-23 81.5 21.8 1.3 1 1 0 1 1 1 1 Amino acid permease Phi-29_GP3 PF05435.6 KFY02291.1 - 0.081 12.1 1.3 0.12 11.5 0.9 1.2 1 0 0 1 1 1 0 Phi-29 DNA terminal protein GP3 YbjM PF11045.3 KFY02291.1 - 0.72 9.6 6.4 5.2 6.8 0.1 3.0 3 0 0 3 3 3 0 Putative inner membrane protein of Enterobacteriaceae Glyco_transf_90 PF05686.7 KFY02292.1 - 3.2e-14 52.4 3.0 2.5e-09 36.3 0.9 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 Ribosomal_L7Ae PF01248.21 KFY02293.1 - 2.5e-28 97.4 1.1 3.3e-28 97.0 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 KFY02293.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family OPT PF03169.10 KFY02294.1 - 1.1e-97 328.0 42.0 1.3e-97 327.8 29.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein RseC_MucC PF04246.7 KFY02294.1 - 5.6 6.5 13.1 6.4 6.3 0.5 3.8 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Beta-lactamase PF00144.19 KFY02296.1 - 1.6e-36 126.0 0.1 3e-36 125.1 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase LRR_4 PF12799.2 KFY02297.1 - 4.1e-33 112.4 57.7 1.9e-07 30.5 4.4 10.8 6 3 4 11 11 11 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KFY02297.1 - 2e-32 110.7 54.9 3.1e-07 30.0 3.2 9.7 7 2 3 10 10 10 8 Leucine rich repeat LRR_1 PF00560.28 KFY02297.1 - 1.5e-20 70.0 54.4 0.017 15.0 0.3 16.8 16 2 1 17 17 17 7 Leucine Rich Repeat LRR_7 PF13504.1 KFY02297.1 - 2.1e-17 60.1 46.7 0.089 13.0 0.0 15.9 16 0 0 16 16 16 6 Leucine rich repeat LRR_6 PF13516.1 KFY02297.1 - 0.011 15.7 52.3 0.73 10.0 0.4 12.8 15 1 1 16 16 16 0 Leucine Rich repeat LRR_9 PF14580.1 KFY02297.1 - 0.012 15.2 14.8 0.09 12.3 0.1 4.2 2 2 2 5 5 5 0 Leucine-rich repeat LRR_2 PF07723.8 KFY02297.1 - 3.8 8.1 7.4 14 6.3 0.3 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat DUF2759 PF10958.3 KFY02300.1 - 0.19 11.3 1.5 14 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) DEAD PF00270.24 KFY02301.1 - 3.3e-40 137.3 0.0 3.7e-39 133.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFY02301.1 - 1.7e-26 91.8 0.2 8.1e-26 89.6 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KFY02301.1 - 1.9e-05 23.6 0.0 3.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KFY02301.1 - 0.052 13.3 0.0 0.17 11.7 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit zf-C2H2_4 PF13894.1 KFY02303.1 - 5.2 7.6 13.7 3.1 8.3 1.2 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger RNase_H PF00075.19 KFY02304.1 - 6e-20 71.9 0.0 7.7e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 KFY02304.1 - 4.6e-05 23.1 0.0 0.0075 16.0 0.0 2.4 2 1 0 2 2 2 2 Reverse transcriptase-like HTH_Tnp_Tc5 PF03221.11 KFY02304.1 - 0.12 12.1 0.2 0.27 11.0 0.2 1.6 1 1 0 1 1 1 0 Tc5 transposase DNA-binding domain Zn_clus PF00172.13 KFY02305.1 - 1.3e-07 31.4 13.0 2.1e-07 30.7 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFY02305.1 - 1.2e-05 24.1 0.0 5.2e-05 22.0 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF3666 PF12408.3 KFY02305.1 - 0.013 14.6 0.7 0.1 11.7 0.0 2.6 3 0 0 3 3 3 0 Ribose-5-phosphate isomerase EzrA PF06160.7 KFY02305.1 - 0.048 11.8 0.1 0.065 11.4 0.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA RTA1 PF04479.8 KFY02306.1 - 3.7e-20 72.3 5.2 7.2e-20 71.4 3.6 1.4 1 1 0 1 1 1 1 RTA1 like protein DUF4325 PF14213.1 KFY02306.1 - 0.18 11.4 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4325) MerC PF03203.9 KFY02306.1 - 2.5 8.4 11.8 0.33 11.3 0.2 2.3 2 0 0 2 2 2 0 MerC mercury resistance protein Pyr_redox_2 PF07992.9 KFY02307.1 - 3.9e-12 46.4 6.6 1.4e-10 41.4 4.6 3.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFY02307.1 - 8.5e-10 38.9 1.1 6.8e-09 36.0 0.6 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFY02307.1 - 7.8e-06 26.0 1.0 0.00032 20.8 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFY02307.1 - 9.4e-05 21.4 11.5 0.016 14.1 0.3 3.9 3 1 1 4 4 4 3 FAD dependent oxidoreductase K_oxygenase PF13434.1 KFY02307.1 - 0.0018 17.2 0.4 0.0036 16.2 0.1 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 KFY02307.1 - 0.0099 14.3 2.9 4.4 5.6 0.1 3.4 4 0 0 4 4 4 1 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 KFY02307.1 - 0.062 12.6 1.2 0.11 11.8 0.3 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Chitin_bind_4 PF00379.18 KFY02307.1 - 0.11 12.7 1.9 2 8.7 0.2 2.7 2 0 0 2 2 2 0 Insect cuticle protein NAD_binding_7 PF13241.1 KFY02307.1 - 0.11 12.7 0.6 0.5 10.6 0.3 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.17 KFY02307.1 - 0.13 11.0 0.1 0.13 11.0 0.0 2.4 2 1 1 3 3 3 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 KFY02307.1 - 0.14 10.7 4.5 0.95 8.0 0.2 2.2 1 1 1 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KFY02307.1 - 0.39 10.4 8.2 4.1 7.1 0.1 3.2 3 1 1 4 4 4 0 FAD-NAD(P)-binding NDT80_PhoG PF05224.7 KFY02308.1 - 2.8e-42 144.8 0.0 5.5e-42 143.8 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Fungal_trans_2 PF11951.3 KFY02310.1 - 2.9e-58 197.3 1.2 3.5e-58 197.0 0.8 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Alpha-L-AF_C PF06964.7 KFY02311.1 - 3.1e-34 118.2 0.3 4.3e-34 117.8 0.2 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Acyl_transf_3 PF01757.17 KFY02312.1 - 5.1e-17 61.7 18.5 6.9e-17 61.2 12.8 1.1 1 0 0 1 1 1 1 Acyltransferase family Sugar_tr PF00083.19 KFY02313.1 - 6.2e-99 331.6 23.7 7.7e-99 331.2 16.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY02313.1 - 6.6e-26 90.8 40.2 1e-18 67.2 10.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily 2OG-FeII_Oxy PF03171.15 KFY02313.1 - 0.00031 20.9 0.0 0.00065 19.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KFY02313.1 - 0.00037 21.0 0.0 0.00087 19.8 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal MatC_N PF07158.6 KFY02313.1 - 1.1 9.1 10.1 0.78 9.5 4.2 2.8 3 0 0 3 3 3 0 Dicarboxylate carrier protein MatC N-terminus Lig_chan PF00060.21 KFY02313.1 - 3.3 7.3 8.5 3.4 7.3 0.3 2.4 2 0 0 2 2 2 0 Ligand-gated ion channel RTA1 PF04479.8 KFY02314.1 - 1.4e-49 168.6 2.8 1.9e-49 168.2 1.9 1.1 1 0 0 1 1 1 1 RTA1 like protein ATP1G1_PLM_MAT8 PF02038.11 KFY02314.1 - 0.0061 15.5 0.1 0.0061 15.5 0.0 2.5 2 0 0 2 2 2 1 ATP1G1/PLM/MAT8 family DUF2127 PF09900.4 KFY02314.1 - 3.2 7.7 8.1 0.48 10.4 0.6 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2127) PLDc_2 PF13091.1 KFY02315.1 - 2.3e-14 53.2 0.0 2.1e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KFY02315.1 - 0.01 15.6 3.8 0.62 9.9 0.0 3.3 4 0 0 4 4 4 0 Phospholipase D Active site motif Methyltransf_23 PF13489.1 KFY02316.1 - 1.2e-21 77.1 0.0 1.7e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY02316.1 - 3.1e-11 43.5 0.0 8.9e-11 42.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY02316.1 - 4.4e-10 39.3 0.0 1.9e-08 34.0 0.0 2.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY02316.1 - 2.9e-09 37.4 0.0 9.3e-08 32.6 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY02316.1 - 2.6e-08 34.2 0.0 9.4e-08 32.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY02316.1 - 1.5e-07 31.6 0.0 1.2e-06 28.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFY02316.1 - 2e-07 30.3 0.0 5.2e-06 25.7 0.0 2.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 KFY02316.1 - 0.002 17.2 0.0 0.0035 16.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 KFY02316.1 - 0.0033 16.4 0.0 0.0077 15.2 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_16 PF10294.4 KFY02316.1 - 0.004 16.6 0.0 0.007 15.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 KFY02316.1 - 0.027 13.8 0.0 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_26 PF13659.1 KFY02316.1 - 0.032 14.2 0.0 0.072 13.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 KFY02316.1 - 0.032 13.7 0.0 0.068 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PASTA PF03793.14 KFY02316.1 - 0.07 12.7 0.1 0.66 9.6 0.0 2.6 2 0 0 2 2 2 0 PASTA domain Methyltransf_8 PF05148.10 KFY02316.1 - 0.11 12.0 0.0 0.37 10.3 0.0 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase Ribosomal_60s PF00428.14 KFY02316.1 - 1.6 9.1 5.3 3.1 8.2 3.0 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein TROVE PF05731.6 KFY02317.1 - 0.047 12.4 2.8 0.15 10.7 0.2 2.1 2 0 0 2 2 2 0 TROVE domain Cluap1 PF10234.4 KFY02317.1 - 0.071 12.3 9.2 0.014 14.5 4.1 1.5 2 0 0 2 2 2 0 Clusterin-associated protein-1 DUF3608 PF12257.3 KFY02318.1 - 6.8e-72 241.7 0.0 1.1e-71 241.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 KFY02318.1 - 1.5e-30 104.7 0.2 3e-30 103.7 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Cu_bind_like PF02298.12 KFY02320.1 - 0.00022 20.9 1.7 0.005 16.6 0.3 2.7 2 1 0 2 2 2 1 Plastocyanin-like domain Copper-bind PF00127.15 KFY02320.1 - 0.025 14.8 0.0 0.076 13.2 0.0 1.9 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Acetyltransf_3 PF13302.1 KFY02321.1 - 3.2e-12 46.8 0.0 5.1e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFY02321.1 - 4.9e-05 23.2 0.2 9.2e-05 22.3 0.1 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Na_Ca_ex PF01699.19 KFY02322.1 - 3.7e-44 149.7 33.5 2.6e-22 78.9 8.5 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein NUC153 PF08159.7 KFY02323.1 - 9.4e-13 47.5 0.1 9.4e-13 47.5 0.1 4.5 5 0 0 5 5 5 2 NUC153 domain DUF1469 PF07332.6 KFY02324.1 - 0.0079 15.9 4.3 0.0079 15.9 3.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1469) AMP-binding PF00501.23 KFY02325.1 - 1.2e-177 590.4 0.0 7.2e-93 311.2 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KFY02325.1 - 9.7e-53 178.9 0.0 2.7e-31 108.5 0.1 2.3 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KFY02325.1 - 1.3e-16 60.6 2.2 1.5e-07 31.5 0.0 3.2 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KFY02325.1 - 3e-13 50.4 0.0 4.1e-07 30.8 0.0 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain ADH_N PF08240.7 KFY02326.1 - 9.6e-07 28.5 0.0 2.4e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFY02326.1 - 8.2e-06 25.3 0.3 1.8e-05 24.2 0.2 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase p450 PF00067.17 KFY02328.1 - 5.7e-67 226.2 0.0 7.5e-67 225.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KFY02329.1 - 1.4e-32 112.8 60.7 1.7e-30 105.9 26.9 3.3 2 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY02329.1 - 2.8e-10 39.3 10.0 2.8e-10 39.3 6.9 2.7 2 1 1 3 3 3 2 Sugar (and other) transporter Fungal_trans PF04082.13 KFY02330.1 - 1.8e-13 49.9 3.3 2.6e-12 46.1 2.3 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY02330.1 - 1.1e-06 28.3 9.9 1.1e-06 28.3 6.9 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 KFY02330.1 - 5.4e-06 26.4 15.6 0.013 15.7 3.2 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFY02330.1 - 5e-05 23.3 20.7 0.027 14.7 5.2 3.9 3 1 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFY02330.1 - 0.0032 17.6 14.7 0.092 13.1 1.5 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger Cytochrom_c3_2 PF14537.1 KFY02330.1 - 0.29 11.4 15.6 0.55 10.6 10.8 1.5 1 0 0 1 1 1 0 Cytochrome c3 Cytochrome_C7 PF14522.1 KFY02330.1 - 7.7 6.2 18.6 0.99 9.0 7.6 2.3 1 1 1 2 2 2 0 Cytochrome c7 DUF1680 PF07944.7 KFY02331.1 - 5.5e-120 401.0 0.0 6.7e-120 400.8 0.0 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) SLT_beta PF02258.11 KFY02331.1 - 0.039 13.7 0.1 3.8 7.4 0.1 2.6 2 0 0 2 2 2 0 Shiga-like toxin beta subunit DUF4097 PF13349.1 KFY02331.1 - 0.079 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) Sugar_tr PF00083.19 KFY02332.1 - 3.6e-67 226.8 23.2 4.4e-67 226.5 16.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY02332.1 - 1.2e-15 57.0 28.9 8.7e-13 47.6 18.5 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily DDE_Tnp_IS1 PF03400.8 KFY02334.1 - 0.029 14.4 0.1 0.061 13.4 0.0 1.5 1 0 0 1 1 1 0 IS1 transposase PPK2 PF03976.9 KFY02334.1 - 0.075 12.3 0.0 6.2 6.0 0.0 2.4 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) DUF3834 PF12916.2 KFY02334.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) MFS_1 PF07690.11 KFY02335.1 - 2.1e-12 46.4 19.3 2.1e-12 46.4 13.4 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF3754 PF12576.3 KFY02335.1 - 0.14 11.7 0.4 0.4 10.3 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3754) Aa_trans PF01490.13 KFY02336.1 - 5.5e-81 272.1 25.2 6.4e-81 271.9 17.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aldedh PF00171.17 KFY02337.1 - 5.3e-135 450.3 0.1 6.3e-135 450.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KFY02337.1 - 0.00042 19.1 0.0 0.0012 17.6 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1720 PF08226.6 KFY02340.1 - 0.013 15.5 0.1 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1720) HMG_box PF00505.14 KFY02343.1 - 4e-11 43.0 0.6 9.7e-11 41.7 0.1 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFY02343.1 - 9.7e-11 41.8 0.2 2e-10 40.8 0.2 1.6 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.25 KFY02343.1 - 1.2e-10 41.3 0.1 2.4e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFY02343.1 - 1.1e-05 25.2 0.1 2.3e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) F-box-like PF12937.2 KFY02366.1 - 6.8e-11 41.7 0.6 2.4e-10 39.9 0.3 2.2 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 KFY02366.1 - 3.8e-08 32.5 18.9 5.5 7.3 0.0 10.9 13 0 0 13 13 13 3 Leucine Rich repeat LRR_4 PF12799.2 KFY02366.1 - 1.2e-07 31.2 10.6 1.7 8.3 0.0 7.2 7 1 0 7 7 7 3 Leucine Rich repeats (2 copies) F-box PF00646.28 KFY02366.1 - 2.8e-06 26.8 0.0 0.00011 21.7 0.0 2.9 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.28 KFY02366.1 - 0.099 12.7 30.0 14 6.1 0.1 9.9 8 3 1 9 9 9 0 Leucine Rich Repeat AMP-binding PF00501.23 KFY02367.1 - 2.7e-70 236.8 0.1 3.3e-70 236.5 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFY02367.1 - 1.2e-16 61.3 0.0 2.4e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LysR_substrate PF03466.15 KFY02367.1 - 0.061 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 LysR substrate binding domain Ribosomal_L13 PF00572.13 KFY02368.1 - 4.5e-27 94.6 0.0 8.8e-27 93.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L13 DSBA PF01323.15 KFY02368.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Glutaredoxin PF00462.19 KFY02369.1 - 9.9e-20 70.2 0.0 1.6e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 KFY02369.1 - 0.0013 18.5 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.1 KFY02369.1 - 0.0023 18.0 0.3 0.012 15.8 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.9 KFY02369.1 - 0.0055 16.9 0.0 0.0074 16.5 0.0 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin PF00085.15 KFY02369.1 - 0.013 15.2 0.1 0.015 15.0 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin DSBA PF01323.15 KFY02369.1 - 0.023 14.2 0.3 0.8 9.2 0.1 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain GST_N_3 PF13417.1 KFY02369.1 - 0.073 13.2 0.0 0.092 12.9 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_4 PF13462.1 KFY02369.1 - 0.085 12.8 1.8 2.8 7.9 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin Chalcone PF02431.10 KFY02370.1 - 1.2e-58 197.7 0.0 1.5e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Rrn6 PF10214.4 KFY02371.1 - 1.9e-91 307.3 0.0 4.1e-91 306.2 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor adh_short PF00106.20 KFY02372.1 - 4.7e-08 33.1 0.0 7.2e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFY02372.1 - 1e-05 25.3 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 KR domain PD40 PF07676.7 KFY02373.1 - 2.9e-47 157.6 25.2 2.5e-07 30.1 0.1 9.7 9 0 0 9 9 9 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 KFY02373.1 - 1.8e-12 46.5 10.5 0.19 10.2 0.4 7.0 3 2 3 6 6 6 5 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1513 PF07433.6 KFY02373.1 - 0.007 15.3 0.0 0.044 12.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1513) Pectate_lyase22 PF14583.1 KFY02373.1 - 0.02 13.3 0.2 1.4 7.3 0.0 3.9 4 1 0 4 4 4 0 Oligogalacturonate lyase TruB_C PF09142.6 KFY02373.1 - 0.052 13.1 0.0 8.5 6.1 0.0 4.3 5 0 0 5 5 5 0 tRNA Pseudouridine synthase II, C terminal Peptidase_S9_N PF02897.10 KFY02373.1 - 0.1 11.1 2.6 1.9 6.9 0.0 3.1 1 1 1 3 3 3 0 Prolyl oligopeptidase, N-terminal beta-propeller domain adh_short PF00106.20 KFY02374.1 - 2.2e-08 34.1 0.0 3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 KFY02374.1 - 0.00018 20.6 0.0 0.00027 20.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KFY02374.1 - 0.00024 21.2 0.0 0.00041 20.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 KFY02374.1 - 0.0046 16.9 0.0 0.0075 16.2 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.5 KFY02374.1 - 0.025 14.2 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 KR domain COesterase PF00135.23 KFY02375.1 - 2.2e-86 290.6 0.0 2.9e-86 290.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFY02375.1 - 8.7e-07 28.7 0.0 9.6e-06 25.3 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFY02375.1 - 0.0003 20.0 0.3 0.00066 18.9 0.2 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family FMN_dh PF01070.13 KFY02377.1 - 4.8e-116 387.5 0.0 5.8e-116 387.2 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 KFY02377.1 - 1.7e-06 27.2 0.0 3.5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 KFY02377.1 - 1.4e-05 24.3 0.1 3.3e-05 23.2 0.0 1.5 1 1 1 2 2 2 1 Nitronate monooxygenase ThiG PF05690.9 KFY02377.1 - 0.00013 21.1 0.0 0.051 12.6 0.0 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 KFY02377.1 - 0.00029 19.8 2.5 0.00081 18.3 0.2 2.4 3 1 1 4 4 4 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.16 KFY02377.1 - 0.027 13.4 0.1 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Dus PF01207.12 KFY02377.1 - 0.067 12.0 0.0 1.8 7.2 0.0 2.4 3 0 0 3 3 3 0 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 KFY02377.1 - 0.076 12.2 0.1 0.48 9.6 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein CbbQ_C PF08406.5 KFY02378.1 - 0.0077 16.2 0.0 0.0083 16.1 0.0 1.1 1 0 0 1 1 1 1 CbbQ/NirQ/NorQ C-terminal Bromodomain PF00439.20 KFY02383.1 - 5.4e-19 67.9 0.2 1.3e-18 66.6 0.1 1.6 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 KFY02383.1 - 9.8e-18 64.0 0.7 5.2e-17 61.7 0.5 2.3 1 0 0 1 1 1 1 Snf2-ATP coupling, chromatin remodelling complex Helicase_C PF00271.26 KFY02383.1 - 3.7e-17 61.9 0.0 6.8e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KFY02383.1 - 1.2e-06 27.6 0.7 2.4e-06 26.5 0.0 1.8 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 SNF2_N PF00176.18 KFY02383.1 - 0.00042 19.2 0.0 0.00067 18.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Trypan_PARP PF05887.6 KFY02383.1 - 4.7 7.0 11.3 12 5.7 7.9 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PQ-loop PF04193.9 KFY02385.1 - 1.1e-21 76.1 19.4 1.3e-11 43.9 1.3 3.5 3 1 1 4 4 4 2 PQ loop repeat Adipogenin PF15202.1 KFY02385.1 - 0.2 11.5 3.5 5.4 6.9 0.2 2.7 2 0 0 2 2 2 0 Adipogenin WD40 PF00400.27 KFY02386.1 - 2.4e-05 24.0 14.1 0.019 14.8 0.0 6.9 7 0 0 7 7 7 3 WD domain, G-beta repeat Nucleoporin_FG PF13634.1 KFY02387.1 - 1.8e-19 70.0 91.3 6.6e-13 48.8 26.9 2.7 1 1 1 2 2 2 2 Nucleoporin FG repeat region PhnA PF03831.9 KFY02389.1 - 1.7 8.1 6.4 3.6 7.0 0.1 2.9 3 0 0 3 3 3 0 PhnA protein PC_rep PF01851.17 KFY02393.1 - 0.068 13.4 0.2 15 6.0 0.0 3.3 4 0 0 4 4 4 0 Proteasome/cyclosome repeat Peptidase_C48 PF02902.14 KFY02404.1 - 2.2e-05 24.2 0.0 3.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GCV_H PF01597.14 KFY02405.1 - 0.068 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein Lge1 PF11488.3 KFY02406.1 - 0.58 10.3 5.1 14 5.9 0.2 2.8 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 Peptidase_M13_N PF05649.8 KFY02407.1 - 0.069 12.1 0.2 0.078 12.0 0.1 1.0 1 0 0 1 1 1 0 Peptidase family M13 bZIP_1 PF00170.16 KFY02407.1 - 0.14 12.1 0.4 0.3 11.0 0.3 1.6 1 0 0 1 1 1 0 bZIP transcription factor Ferric_reduct PF01794.14 KFY02408.1 - 1.8e-09 37.7 9.9 1.8e-09 37.7 6.9 2.8 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KFY02408.1 - 2.1e-08 33.9 0.0 5.2e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KFY02408.1 - 3.8e-07 30.1 0.0 6.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4112 PF13430.1 KFY02408.1 - 0.038 13.9 3.2 1 9.3 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4112) SRF-TF PF00319.13 KFY02409.1 - 0.00027 20.0 0.0 0.00047 19.3 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Laminin_II PF06009.7 KFY02411.1 - 0.032 13.9 0.4 0.066 12.9 0.3 1.5 1 0 0 1 1 1 0 Laminin Domain II eIF3_N PF09440.5 KFY02411.1 - 0.23 11.6 1.9 0.44 10.7 0.1 2.0 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain IncA PF04156.9 KFY02414.1 - 0.013 15.0 0.3 0.017 14.7 0.2 1.1 1 0 0 1 1 1 0 IncA protein Thioredoxin PF00085.15 KFY02429.1 - 7.8e-39 131.5 0.3 3e-24 84.6 0.0 4.0 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 KFY02429.1 - 2e-14 53.8 0.0 2.1e-07 30.9 0.0 4.4 3 1 2 5 5 5 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KFY02429.1 - 1.3e-07 31.5 0.4 0.017 15.2 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KFY02429.1 - 5.4e-06 26.5 6.3 0.023 14.8 0.0 4.5 4 2 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_3 PF13192.1 KFY02429.1 - 7.4e-06 25.6 0.0 0.085 12.6 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin domain Thioredoxin_7 PF13899.1 KFY02429.1 - 0.00027 20.9 0.3 0.0051 16.8 0.0 2.8 3 0 0 3 3 3 1 Thioredoxin-like HyaE PF07449.6 KFY02429.1 - 0.011 15.6 0.0 7.2 6.5 0.0 2.8 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE TraF PF13728.1 KFY02429.1 - 0.016 14.7 0.1 3.5 7.0 0.0 3.0 3 1 1 4 4 4 0 F plasmid transfer operon protein HAD_2 PF13419.1 KFY02431.1 - 2e-27 96.5 0.0 2.4e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFY02431.1 - 0.0011 19.4 0.0 0.0017 18.7 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pox_F12L PF03337.8 KFY02431.1 - 0.059 11.2 0.0 0.073 10.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus F12L protein bZIP_1 PF00170.16 KFY02432.1 - 5e-06 26.3 3.2 8.3e-06 25.6 2.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFY02432.1 - 1.3e-05 24.8 3.8 2.3e-05 24.1 2.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFY02432.1 - 0.00036 20.7 5.1 0.0008 19.6 3.5 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF2730 PF10805.3 KFY02432.1 - 0.027 14.1 0.8 0.047 13.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF1635 PF07795.6 KFY02432.1 - 2 7.7 6.0 0.3 10.4 0.7 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1635) TPR_10 PF13374.1 KFY02433.1 - 8.6e-25 85.8 5.4 3.2e-07 30.0 0.0 5.2 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 KFY02433.1 - 1.3e-23 82.7 7.0 1.3e-11 44.3 0.4 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFY02433.1 - 1.6e-12 47.6 1.0 2.7e-05 24.6 0.1 3.3 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFY02433.1 - 1.7e-12 46.2 6.8 0.0047 16.7 0.0 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFY02433.1 - 1.1e-11 44.2 5.4 0.028 15.0 0.0 5.5 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_20 PF14561.1 KFY02433.1 - 3.5e-11 43.0 6.6 0.053 13.6 0.1 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFY02433.1 - 3.1e-09 35.9 5.5 0.085 12.6 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFY02433.1 - 1e-08 34.7 2.8 0.0011 18.5 0.1 3.0 2 1 0 2 2 2 2 TPR repeat TPR_6 PF13174.1 KFY02433.1 - 2.1e-08 34.0 6.8 0.094 13.2 0.0 4.6 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFY02433.1 - 2.5e-07 29.9 3.9 0.09 12.5 0.0 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat NB-ARC PF00931.17 KFY02433.1 - 5.5e-07 28.7 0.0 1.4e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain Apc3 PF12895.2 KFY02433.1 - 5.6e-07 29.6 7.7 0.00092 19.2 0.0 4.7 3 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KFY02433.1 - 8.5e-07 29.2 17.3 0.00085 19.6 1.0 5.1 4 2 2 6 6 4 2 Tetratricopeptide repeat PGAP1 PF07819.8 KFY02433.1 - 2.3e-06 27.3 0.0 5.1e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein PPR PF01535.15 KFY02433.1 - 2.4e-06 27.1 0.3 2.7 8.1 0.0 4.8 5 0 0 5 5 3 1 PPR repeat Abhydrolase_6 PF12697.2 KFY02433.1 - 3.5e-06 27.0 0.0 1.2e-05 25.3 0.0 1.9 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_22 PF13401.1 KFY02433.1 - 7.7e-06 26.0 0.0 3.4e-05 24.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain UPF0052 PF01933.13 KFY02433.1 - 2.2e-05 23.9 0.6 0.52 9.5 0.0 4.5 2 1 2 4 4 4 1 Uncharacterised protein family UPF0052 TPR_1 PF00515.23 KFY02433.1 - 2.8e-05 23.5 6.3 1.3 8.7 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_16 PF13191.1 KFY02433.1 - 9.6e-05 22.4 1.7 0.00056 19.9 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain TPR_4 PF07721.9 KFY02433.1 - 0.00013 22.1 6.4 0.1 13.0 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Abhydrolase_5 PF12695.2 KFY02433.1 - 0.00017 21.3 0.1 0.00076 19.2 0.0 2.1 3 0 0 3 3 1 1 Alpha/beta hydrolase family TPR_17 PF13431.1 KFY02433.1 - 0.0002 21.2 0.7 2 8.7 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2305 PF10230.4 KFY02433.1 - 0.00021 20.8 0.2 0.1 11.9 0.0 2.9 2 1 1 3 3 3 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_9 PF10081.4 KFY02433.1 - 0.00046 18.9 0.0 0.014 14.1 0.0 2.3 2 0 0 2 2 2 1 Alpha/beta-hydrolase family CbiA PF01656.18 KFY02433.1 - 0.00059 19.2 0.0 0.0012 18.2 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain LCAT PF02450.10 KFY02433.1 - 0.0016 17.5 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF726 PF05277.7 KFY02433.1 - 0.0022 16.9 0.2 0.049 12.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF726) CheW PF01584.14 KFY02433.1 - 0.0036 16.7 0.8 13 5.2 0.0 4.3 1 1 3 4 4 4 0 CheW-like domain AAA_14 PF13173.1 KFY02433.1 - 0.011 15.6 0.0 0.095 12.6 0.0 2.5 3 0 0 3 3 2 0 AAA domain DUF676 PF05057.9 KFY02433.1 - 0.027 13.7 0.0 0.09 12.0 0.0 1.8 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Vps39_1 PF10366.4 KFY02433.1 - 0.039 13.9 4.1 12 5.9 0.1 4.0 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 1 SRP54 PF00448.17 KFY02433.1 - 0.062 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PPR_2 PF13041.1 KFY02433.1 - 0.13 12.2 0.1 29 4.7 0.0 3.4 3 0 0 3 3 3 0 PPR repeat family Cutinase PF01083.17 KFY02433.1 - 0.18 11.5 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 Cutinase PPR_1 PF12854.2 KFY02433.1 - 0.37 10.3 4.7 20 4.7 0.0 3.7 4 0 0 4 4 3 0 PPR repeat Fis1_TPR_N PF14852.1 KFY02433.1 - 0.52 9.6 3.8 3.9 6.8 0.1 3.3 3 0 0 3 3 3 0 Fis1 N-terminal tetratricopeptide repeat TPR_21 PF09976.4 KFY02433.1 - 0.58 10.0 7.3 3.6 7.5 0.2 3.1 2 1 0 3 3 2 0 Tetratricopeptide repeat Gly_transf_sug PF04488.10 KFY02434.1 - 2.4e-09 37.4 0.0 5.3e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KFY02434.1 - 0.0033 15.9 0.1 0.0051 15.3 0.0 1.1 1 0 0 1 1 1 1 TcdA/TcdB catalytic glycosyltransferase domain Fungal_trans PF04082.13 KFY02436.1 - 6.3e-15 54.7 0.0 9.7e-15 54.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY02436.1 - 1.8e-06 27.7 9.7 3.3e-06 26.9 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YhhN PF07947.9 KFY02438.1 - 4.5e-37 127.2 6.5 4.5e-37 127.2 4.5 2.0 2 0 0 2 2 2 1 YhhN-like protein Esterase_phd PF10503.4 KFY02438.1 - 5.6e-20 71.5 0.1 9.1e-20 70.8 0.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KFY02438.1 - 1.8e-08 33.8 0.7 2.9e-08 33.1 0.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFY02438.1 - 0.00078 19.2 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY02438.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold UCR_Fe-S_N PF10399.4 KFY02438.1 - 2.9 7.1 6.4 0.19 10.9 0.4 2.2 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DHquinase_I PF01487.10 KFY02439.1 - 1.5e-39 135.9 0.0 2.4e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 KFY02439.1 - 2.6e-17 63.1 0.7 7.6e-17 61.6 0.1 2.0 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 KFY02439.1 - 5e-16 58.5 0.0 1.3e-15 57.1 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KFY02439.1 - 1e-10 41.8 0.0 2.3e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.1 KFY02439.1 - 0.023 14.5 0.0 0.5 10.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Fungal_trans PF04082.13 KFY02440.1 - 1.8e-17 63.0 0.1 3.1e-17 62.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY02440.1 - 4.4e-07 29.7 13.6 7.3e-07 28.9 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Inositol_P PF00459.20 KFY02441.1 - 1.9e-72 243.7 0.0 2.2e-72 243.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Shikimate_dh_N PF08501.6 KFY02442.1 - 1.1e-21 76.6 0.0 2e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KFY02442.1 - 1.9e-14 53.9 0.0 2.8e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.19 KFY02443.1 - 4.4e-130 434.2 23.4 5e-130 434.0 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY02443.1 - 3.4e-20 72.0 39.1 1.9e-18 66.3 26.4 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily PIG-P PF08510.7 KFY02443.1 - 2 8.0 6.1 5.2 6.7 3.4 2.2 1 1 0 1 1 1 0 PIG-P AP_endonuc_2 PF01261.19 KFY02444.1 - 4.3e-29 101.3 0.0 1.1e-28 100.0 0.0 1.6 2 1 0 2 2 2 1 Xylose isomerase-like TIM barrel CHAP PF05257.11 KFY02446.1 - 1.2e-19 70.1 2.2 2.1e-19 69.4 1.5 1.3 1 0 0 1 1 1 1 CHAP domain SH3_3 PF08239.6 KFY02446.1 - 8.1e-06 25.9 0.0 2.9e-05 24.1 0.0 2.0 1 0 0 1 1 1 1 Bacterial SH3 domain Cellulase PF00150.13 KFY02447.1 - 2.2e-30 105.8 0.4 4.1e-30 104.9 0.3 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_20 PF00728.17 KFY02448.1 - 8.4e-38 130.4 0.1 3.1e-37 128.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 KFY02448.1 - 1.2e-09 38.7 0.0 2.4e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Collagen PF01391.13 KFY02450.1 - 0.065 12.7 13.3 0.16 11.5 9.2 1.6 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Herpes_DNAp_acc PF04929.7 KFY02450.1 - 7.6 5.3 6.9 22 3.8 4.8 1.9 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Sugar_tr PF00083.19 KFY02454.1 - 4.4e-63 213.4 23.9 3.6e-45 154.3 2.5 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFY02454.1 - 3.1e-19 68.9 25.1 1.9e-11 43.3 7.2 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KFY02455.1 - 6.5e-36 123.7 45.0 6.5e-36 123.7 31.2 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFY02455.1 - 1.1e-09 37.0 24.3 1.1e-09 37.0 16.8 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KFY02455.1 - 5.5e-09 35.1 18.2 2.6e-08 32.9 4.0 3.9 2 1 2 4 4 4 2 Sugar (and other) transporter GYF PF02213.11 KFY02456.1 - 4.2e-10 39.0 0.2 7.7e-10 38.2 0.1 1.5 1 0 0 1 1 1 1 GYF domain Med2 PF11214.3 KFY02456.1 - 3 7.9 5.4 15 5.6 3.8 2.0 1 1 1 2 2 2 0 Mediator complex subunit 2 UFD1 PF03152.9 KFY02457.1 - 5.7e-72 240.5 0.0 7.4e-72 240.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Pyridox_ox_2 PF12900.2 KFY02468.1 - 0.019 14.7 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase MIT PF04212.13 KFY02469.1 - 0.024 14.4 0.6 0.052 13.4 0.4 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 KFY02470.1 - 4.9e-07 30.5 0.0 2e-06 28.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFY02470.1 - 2.8e-06 27.6 0.0 1.3e-05 25.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 KFY02470.1 - 5.3e-06 26.1 0.0 7.2e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.17 KFY02470.1 - 0.00022 20.1 0.0 0.0004 19.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Zeta_toxin PF06414.7 KFY02470.1 - 0.00027 20.0 0.3 0.027 13.5 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 KFY02470.1 - 0.0007 19.6 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 KFY02470.1 - 0.00075 19.3 0.0 0.013 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFY02470.1 - 0.0017 18.4 0.0 0.0027 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFY02470.1 - 0.0019 17.9 0.4 0.0065 16.1 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain Thymidylate_kin PF02223.12 KFY02470.1 - 0.0071 15.7 0.0 0.31 10.3 0.0 2.3 2 0 0 2 2 2 1 Thymidylate kinase NTPase_1 PF03266.10 KFY02470.1 - 0.0095 15.6 0.1 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA PF00004.24 KFY02470.1 - 0.013 15.6 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 KFY02470.1 - 0.016 14.1 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RuvB_N PF05496.7 KFY02470.1 - 0.018 14.0 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus T2SE PF00437.15 KFY02470.1 - 0.022 13.6 0.0 0.035 13.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 KFY02470.1 - 0.022 14.4 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain KTI12 PF08433.5 KFY02470.1 - 0.029 13.6 0.1 0.06 12.5 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_25 PF13481.1 KFY02470.1 - 0.029 13.7 0.0 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KFY02470.1 - 0.029 13.8 0.4 0.061 12.7 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 KFY02470.1 - 0.035 14.4 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter APS_kinase PF01583.15 KFY02470.1 - 0.044 13.4 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase ArgK PF03308.11 KFY02470.1 - 0.052 12.3 0.0 0.082 11.6 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_11 PF13086.1 KFY02470.1 - 0.058 12.9 0.0 0.086 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KFY02470.1 - 0.061 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KFY02470.1 - 0.075 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Viral_helicase1 PF01443.13 KFY02470.1 - 0.08 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 KFY02470.1 - 0.084 12.2 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain UPF0079 PF02367.12 KFY02470.1 - 0.1 12.2 0.0 0.28 10.8 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_14 PF13173.1 KFY02470.1 - 0.15 11.9 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mur_ligase_M PF08245.7 KFY02471.1 - 5e-07 29.9 0.1 8.5e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 Mur ligase middle domain Pkinase PF00069.20 KFY02472.1 - 7e-69 231.8 0.0 1.2e-68 231.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY02472.1 - 4.2e-49 166.9 0.0 6.5e-49 166.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFY02472.1 - 0.00054 19.0 0.0 0.0013 17.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Asp PF00026.18 KFY02474.1 - 2.6e-11 43.3 0.9 4.2e-11 42.6 0.6 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease DUF4448 PF14610.1 KFY02474.1 - 0.023 14.1 0.0 0.048 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Herpes_gE PF02480.11 KFY02474.1 - 0.024 12.9 0.0 0.043 12.0 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF912 PF06024.7 KFY02474.1 - 0.032 14.2 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 KFY02474.1 - 0.17 11.5 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family EphA2_TM PF14575.1 KFY02474.1 - 0.2 12.0 1.1 0.44 10.9 0.7 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Glyco_hydro_88 PF07470.8 KFY02475.1 - 3.8e-14 52.4 0.1 5.5e-14 51.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 AcetylCoA_hydro PF02550.10 KFY02476.1 - 2.1e-49 168.0 0.0 3.4e-49 167.2 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 KFY02476.1 - 3.4e-39 133.9 0.0 5.6e-39 133.2 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.18 KFY02476.1 - 0.075 12.1 0.0 0.19 10.9 0.0 1.7 1 0 0 1 1 1 0 Coenzyme A transferase Glyco_hydro_35 PF01301.14 KFY02477.1 - 1.9e-84 283.7 0.0 3.3e-84 282.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 KFY02477.1 - 6.6e-65 217.8 2.4 6.6e-65 217.8 1.7 1.8 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 IF-2B PF01008.12 KFY02477.1 - 2.8e-59 200.4 10.7 4.6e-35 120.9 0.0 3.1 3 1 0 3 3 3 2 Initiation factor 2 subunit family BetaGal_dom4_5 PF13364.1 KFY02477.1 - 1e-47 161.0 11.4 1e-25 90.1 3.8 2.7 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 KFY02477.1 - 5.3e-23 80.2 0.1 1.2e-22 79.1 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 DUF4646 PF15496.1 KFY02477.1 - 0.00056 19.9 0.0 0.0017 18.3 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) Allexi_40kDa PF05549.6 KFY02477.1 - 0.22 10.7 1.5 0.43 9.8 0.1 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein NIF PF03031.13 KFY02478.1 - 1.4e-52 177.5 0.0 2.1e-52 176.9 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF3435 PF11917.3 KFY02480.1 - 4.7e-74 249.5 0.0 5.6e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-C2H2 PF00096.21 KFY02481.1 - 7e-17 60.6 26.9 6.4e-05 23.0 1.1 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFY02481.1 - 5.5e-12 45.3 28.2 9.8e-07 28.7 0.1 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFY02481.1 - 2.3e-10 40.0 22.4 0.0015 18.7 0.8 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KFY02481.1 - 0.15 12.0 0.0 0.15 12.0 0.0 3.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.2 KFY02481.1 - 0.16 12.2 6.8 7.4 6.9 0.3 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KFY02481.1 - 0.45 10.7 4.5 0.55 10.4 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Ogr_Delta PF04606.7 KFY02481.1 - 1.5 8.5 11.3 3.2 7.5 0.6 2.9 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger Zn-ribbon_8 PF09723.5 KFY02481.1 - 2.6 8.0 14.5 0.53 10.2 1.8 3.9 3 1 0 3 3 3 0 Zinc ribbon domain zf-LYAR PF08790.6 KFY02481.1 - 3.8 7.3 5.8 3.1 7.5 0.0 3.1 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger Dicty_CAR PF05462.6 KFY02483.1 - 3.3e-12 45.9 16.6 2.5e-11 43.0 7.7 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor Git3 PF11710.3 KFY02483.1 - 4.3e-09 36.2 12.8 4.3e-09 36.2 8.8 1.9 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 KFY02483.1 - 6.1e-09 35.3 0.3 1e-08 34.6 0.2 1.4 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Tho2 PF11262.3 KFY02485.1 - 4.4e-83 278.7 0.0 7.5e-83 278.0 0.0 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 KFY02485.1 - 1.4e-26 92.1 1.1 3.1e-26 90.9 0.0 2.3 3 0 0 3 3 3 1 Transcription- and export-related complex subunit Abhydrolase_1 PF00561.15 KFY02486.1 - 1.8e-20 73.4 0.1 2.4e-20 73.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KFY02486.1 - 2.7e-08 33.9 0.2 3.6e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KFY02486.1 - 0.057 12.0 0.0 0.069 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) HATPase_c PF02518.21 KFY02488.1 - 1.6e-22 79.3 0.2 4.1e-22 77.9 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.6 KFY02488.1 - 2.7e-20 72.2 3.3 1.5e-10 41.0 1.2 3.7 3 0 0 3 3 3 3 PAS fold Response_reg PF00072.19 KFY02488.1 - 4.6e-20 71.6 0.1 4.6e-19 68.4 0.0 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KFY02488.1 - 1.7e-19 69.5 0.0 5.7e-19 67.8 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 KFY02488.1 - 3.7e-15 56.1 0.0 3e-07 30.7 0.0 3.6 2 1 0 2 2 2 2 PAS domain PAS_4 PF08448.5 KFY02488.1 - 1.2e-09 38.1 0.2 8.6e-06 25.7 0.1 3.7 3 0 0 3 3 3 2 PAS fold PAS PF00989.19 KFY02488.1 - 7.7e-09 35.3 0.0 0.0053 16.5 0.0 3.0 2 0 0 2 2 2 2 PAS fold UPF0565 PF10561.4 KFY02488.1 - 0.016 14.1 0.0 0.035 12.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 PAS_8 PF13188.1 KFY02488.1 - 0.11 12.4 0.0 4.8 7.1 0.0 2.6 2 0 0 2 2 2 0 PAS domain Carb_kinase PF01256.12 KFY02490.1 - 5.8e-55 186.2 0.0 8.2e-55 185.7 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 KFY02490.1 - 0.021 13.9 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family PARP PF00644.15 KFY02491.1 - 6.3e-11 42.0 0.3 3.9e-10 39.5 0.2 2.1 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 KFY02491.1 - 1.7e-08 33.9 0.0 3.7e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KFY02491.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 RWD domain Sds3 PF08598.6 KFY02492.1 - 1e-35 123.1 0.0 1.8e-35 122.3 0.0 1.6 1 1 0 1 1 1 1 Sds3-like Nop PF01798.13 KFY02493.1 - 6.6e-55 184.5 1.6 2.8e-54 182.4 1.1 2.2 1 1 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KFY02493.1 - 4.8e-24 83.9 0.2 9.1e-24 83.0 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KFY02493.1 - 4.4e-21 74.8 2.1 4.4e-21 74.8 1.5 3.0 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DUF760 PF05542.6 KFY02493.1 - 0.026 14.6 0.1 0.28 11.4 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF760) vATP-synt_AC39 PF01992.11 KFY02494.1 - 1.3e-116 389.4 0.0 1.4e-116 389.2 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ribosomal_S15 PF00312.17 KFY02495.1 - 3e-18 65.3 0.3 6.7e-18 64.2 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S15 Ribosomal_S2 PF00318.15 KFY02496.1 - 2.4e-44 151.0 0.2 2.7e-23 82.3 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 zf-RING_2 PF13639.1 KFY02499.1 - 1.3e-11 44.1 3.6 2.6e-11 43.1 2.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KFY02499.1 - 5.5e-11 42.4 0.5 1.1e-10 41.4 0.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KFY02499.1 - 3.4e-06 26.8 0.5 6.4e-06 25.9 0.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 KFY02499.1 - 2e-05 24.2 3.2 3.3e-05 23.5 2.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFY02499.1 - 2.4e-05 23.9 1.6 4.2e-05 23.1 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFY02499.1 - 0.0002 21.3 4.8 0.00044 20.2 3.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFY02499.1 - 0.00036 20.1 4.1 0.00063 19.3 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KFY02499.1 - 0.0039 17.1 5.6 0.057 13.3 3.9 2.3 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KFY02499.1 - 0.006 16.2 2.2 0.013 15.2 1.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-P11 PF03854.9 KFY02499.1 - 0.068 12.6 1.4 0.16 11.4 0.9 1.6 1 0 0 1 1 1 0 P-11 zinc finger MFS_1 PF07690.11 KFY02501.1 - 3.1e-39 134.6 26.6 3.1e-39 134.6 18.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Tweety PF04906.8 KFY02501.1 - 0.014 13.7 1.1 0.027 12.9 0.8 1.3 1 0 0 1 1 1 0 Tweety Fungal_trans PF04082.13 KFY02502.1 - 5.4e-08 32.0 0.6 1e-07 31.1 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY02502.1 - 6.6e-07 29.1 10.4 9.9e-07 28.5 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_C48 PF02902.14 KFY02508.1 - 1.4e-05 24.8 0.0 3e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PHD PF00628.24 KFY02508.1 - 0.33 10.6 4.9 0.68 9.6 3.4 1.5 1 0 0 1 1 1 0 PHD-finger AT_hook PF02178.14 KFY02508.1 - 0.77 9.6 9.8 0.16 11.7 3.4 2.7 2 0 0 2 2 2 0 AT hook motif SLA_LP_auto_ag PF05889.8 KFY02509.1 - 0.13 10.6 0.5 0.37 9.2 0.0 1.7 1 1 1 2 2 2 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) IncFII_repA PF02387.10 KFY02509.1 - 2.5 7.1 10.9 4.6 6.3 7.5 1.4 1 0 0 1 1 1 0 IncFII RepA protein family Kinesin PF00225.18 KFY02520.1 - 3.5e-80 269.2 0.0 5.9e-80 268.4 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain HHH PF00633.18 KFY02520.1 - 0.0012 18.4 0.4 0.48 10.2 0.0 2.8 2 0 0 2 2 2 2 Helix-hairpin-helix motif HHH_3 PF12836.2 KFY02520.1 - 0.011 15.6 0.0 0.033 14.1 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.1 KFY02520.1 - 0.075 13.2 0.2 1.1 9.5 0.1 2.3 1 1 1 2 2 2 0 Helix-hairpin-helix domain AIM24 PF01987.12 KFY02521.1 - 5.9e-47 159.9 0.0 8.5e-47 159.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 MFS_1 PF07690.11 KFY02521.1 - 1.5e-28 99.5 70.2 1.4e-26 93.0 32.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KFY02521.1 - 4.2 7.2 18.6 0.017 14.8 2.8 3.8 4 1 1 5 5 5 0 MFS_1 like family SBF PF01758.11 KFY02522.1 - 1.5e-46 158.1 16.1 1.5e-46 158.1 11.1 2.5 2 2 2 4 4 4 2 Sodium Bile acid symporter family Rhodanese PF00581.15 KFY02523.1 - 6.4e-09 36.1 0.0 1.1e-08 35.3 0.0 1.4 1 1 0 1 1 1 1 Rhodanese-like domain Macoilin PF09726.4 KFY02524.1 - 6.6 4.8 22.4 9.1 4.4 15.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Redoxin PF08534.5 KFY02525.1 - 1.9e-26 92.3 0.0 2.2e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KFY02525.1 - 2.8e-06 27.0 0.0 3.6e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family 2-Hacid_dh_C PF02826.14 KFY02529.1 - 1.4e-52 177.4 0.0 2.2e-52 176.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFY02529.1 - 2e-12 46.7 0.0 2.2e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFY02529.1 - 1.9e-05 24.5 0.0 2.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KFY02529.1 - 0.0002 20.7 0.0 0.00029 20.2 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 KFY02529.1 - 0.016 15.6 0.0 0.031 14.6 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KFY02529.1 - 0.032 13.8 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KFY02529.1 - 0.07 13.2 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.16 KFY02529.1 - 0.094 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain MFS_1 PF07690.11 KFY02530.1 - 5.7e-33 114.0 31.8 7.8e-33 113.6 22.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_47 PF01532.15 KFY02531.1 - 6e-157 522.9 0.0 7.1e-157 522.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4245 PF14030.1 KFY02531.1 - 0.15 11.7 0.2 0.82 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) DNA_pol3_a_NII PF11490.3 KFY02531.1 - 9.1 5.9 8.5 17 5.0 5.9 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Clathrin PF00637.15 KFY02532.1 - 9.1e-18 64.2 0.6 6.5e-17 61.4 0.1 2.5 2 1 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 KFY02532.1 - 0.00024 20.8 2.6 0.074 12.9 0.5 4.1 3 1 0 3 3 3 1 WD domain, G-beta repeat zf-RING_2 PF13639.1 KFY02532.1 - 0.0015 18.3 0.3 0.0033 17.2 0.2 1.7 1 0 0 1 1 1 1 Ring finger domain Vps39_1 PF10366.4 KFY02532.1 - 0.025 14.5 0.2 0.1 12.6 0.0 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 zf-RING_5 PF14634.1 KFY02532.1 - 0.056 13.1 0.2 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain CDC45 PF02724.9 KFY02532.1 - 4.6 5.1 7.6 7.2 4.5 5.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 KFY02532.1 - 5.8 6.4 12.9 18 4.8 9.0 1.8 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF155 PF02582.9 KFY02533.1 - 8.7e-39 133.2 0.0 1.6e-38 132.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Apc1 PF12859.2 KFY02533.1 - 1.7e-27 95.7 0.1 5.7e-27 93.9 0.1 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 KFY02533.1 - 0.0037 17.4 1.9 12 6.3 0.1 4.3 4 0 0 4 4 4 1 Proteasome/cyclosome repeat Ank_2 PF12796.2 KFY02534.1 - 5e-19 68.4 0.1 7.1e-19 67.9 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFY02534.1 - 7.2e-19 66.5 0.4 4.6e-11 41.9 0.3 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KFY02534.1 - 1.6e-16 60.3 0.3 1.3e-07 31.9 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY02534.1 - 3.9e-16 58.6 2.4 2.9e-09 36.8 0.2 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY02534.1 - 1.1e-13 49.9 0.0 3.5e-07 29.8 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat ECH PF00378.15 KFY02535.1 - 4.2e-48 163.6 0.7 2.8e-44 151.0 0.2 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Cpn60_TCP1 PF00118.19 KFY02536.1 - 1.2e-144 482.5 0.1 1.3e-144 482.4 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Prenylcys_lyase PF07156.9 KFY02537.1 - 6.5e-31 107.5 0.0 3.1e-29 102.0 0.0 2.1 1 1 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 KFY02537.1 - 9.8e-13 47.9 0.0 1.9e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KFY02537.1 - 2e-11 43.6 0.0 3.9e-07 29.5 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 KFY02537.1 - 2.2e-09 36.6 0.0 6.6e-06 25.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KFY02537.1 - 2e-05 24.3 0.1 0.00017 21.4 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KFY02537.1 - 0.0011 19.1 0.0 0.12 12.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFY02537.1 - 0.0026 16.9 0.1 0.005 15.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KFY02537.1 - 0.0058 16.5 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFY02537.1 - 0.0064 16.8 0.1 0.15 12.4 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KFY02537.1 - 0.017 14.5 0.1 0.047 13.1 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Malic_M PF03949.10 KFY02537.1 - 0.021 14.3 0.1 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Shikimate_DH PF01488.15 KFY02537.1 - 0.12 12.4 0.0 0.32 11.1 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ribosomal_S26e PF01283.14 KFY02538.1 - 7.1e-51 171.2 7.5 8.5e-51 171.0 5.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Zn_ribbon_2 PF12674.2 KFY02538.1 - 0.034 14.5 0.2 7.1 7.0 0.0 2.3 1 1 1 2 2 2 0 Putative zinc ribbon domain DUF1918 PF08940.6 KFY02538.1 - 0.036 13.4 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Fer4_7 PF12838.2 KFY02538.1 - 0.08 13.3 1.5 1.4 9.3 0.3 2.3 2 1 0 2 2 2 0 4Fe-4S dicluster domain Ribosomal_S27 PF01599.14 KFY02539.1 - 1.1e-27 95.5 2.1 1.1e-27 95.5 1.4 1.8 2 0 0 2 2 2 1 Ribosomal protein S27a IBR PF01485.16 KFY02539.1 - 0.016 15.0 1.1 0.023 14.5 0.4 1.7 1 1 0 1 1 1 0 IBR domain Cucumo_2B PF03263.8 KFY02539.1 - 0.072 13.3 0.3 0.086 13.1 0.2 1.2 1 0 0 1 1 1 0 Cucumovirus protein 2B Glyco_hydro_18 PF00704.23 KFY02540.1 - 2.1e-97 326.6 0.6 2.4e-97 326.4 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DnaJ PF00226.26 KFY02541.1 - 1.6e-09 37.3 0.5 4.1e-09 36.0 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain Nfu_N PF08712.6 KFY02546.1 - 1.8e-30 104.3 0.0 4.9e-30 102.9 0.0 1.7 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 KFY02546.1 - 6.8e-21 73.8 0.1 1e-20 73.2 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain Med21 PF11221.3 KFY02551.1 - 0.24 11.3 2.0 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Aminotran_3 PF00202.16 KFY02552.1 - 1.7e-58 198.1 0.5 2.2e-37 128.7 0.0 2.3 1 1 1 2 2 2 2 Aminotransferase class-III Pkinase PF00069.20 KFY02553.1 - 0.00012 21.3 0.0 0.00012 21.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 KFY02553.1 - 0.0052 16.5 0.1 0.0052 16.5 0.0 3.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family DDRGK PF09756.4 KFY02553.1 - 6.2 6.1 21.8 14 5.0 15.1 1.6 1 0 0 1 1 1 0 DDRGK domain APH PF01636.18 KFY02556.1 - 1.3e-15 57.8 0.0 2.2e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFY02556.1 - 0.0034 16.9 0.0 0.0074 15.8 0.0 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Cytokin_check_N PF10407.4 KFY02558.1 - 1.9e-05 24.1 0.0 3.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus AAA PF00004.24 KFY02559.1 - 2.6e-27 95.6 0.0 4.9e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KFY02559.1 - 8.1e-06 25.5 0.0 0.0057 16.2 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 KFY02559.1 - 2.6e-05 23.8 0.1 6.2e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KFY02559.1 - 0.00012 22.2 0.6 0.00066 19.8 0.3 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFY02559.1 - 0.00013 22.0 0.3 0.00029 20.8 0.2 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 KFY02559.1 - 0.00013 21.6 0.0 0.00026 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KFY02559.1 - 0.00063 18.8 0.0 0.0014 17.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 KFY02559.1 - 0.00095 19.3 0.0 0.0025 17.9 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.1 KFY02559.1 - 0.0032 18.2 0.0 0.011 16.5 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.9 KFY02559.1 - 0.0046 16.8 0.0 0.045 13.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KFY02559.1 - 0.0053 16.6 0.0 0.014 15.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_31 PF13614.1 KFY02559.1 - 0.0062 16.4 0.1 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 KFY02559.1 - 0.0078 15.2 0.4 0.023 13.7 0.1 1.8 1 1 1 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 KFY02559.1 - 0.0097 15.3 0.5 0.029 13.7 0.3 1.8 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 KFY02559.1 - 0.011 14.4 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.1 KFY02559.1 - 0.013 15.8 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFY02559.1 - 0.018 14.7 0.3 0.054 13.1 0.2 1.8 1 1 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 KFY02559.1 - 0.022 13.7 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 KFY02559.1 - 0.023 14.1 0.2 0.064 12.6 0.1 1.8 1 1 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 KFY02559.1 - 0.026 13.6 0.0 0.065 12.3 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.1 KFY02559.1 - 0.029 14.2 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 KFY02559.1 - 0.045 12.9 0.0 0.081 12.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.1 KFY02559.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KFY02559.1 - 0.052 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 KFY02559.1 - 0.065 12.3 0.5 8.7 5.3 0.1 2.2 1 1 1 2 2 2 0 KaiC CbiA PF01656.18 KFY02559.1 - 0.094 12.1 0.1 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.1 KFY02559.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Telomerase_RBD PF12009.3 KFY02560.1 - 5.5e-43 146.1 0.2 1.4e-42 144.7 0.1 1.8 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 KFY02560.1 - 9.6e-17 61.0 0.0 8.5e-16 57.9 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RhoGEF PF00621.15 KFY02561.1 - 2.5e-35 121.9 0.3 1.3e-34 119.6 0.0 2.2 2 0 0 2 2 2 1 RhoGEF domain BAR PF03114.13 KFY02561.1 - 1.4e-08 34.5 1.8 1.4e-08 34.5 1.2 2.0 2 0 0 2 2 2 1 BAR domain TPR_10 PF13374.1 KFY02562.1 - 1.1e-23 82.4 3.5 1.3e-09 37.6 0.2 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFY02562.1 - 6.9e-19 67.5 1.7 2e-09 37.2 0.1 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFY02562.1 - 3.4e-13 48.9 3.9 0.00022 21.5 0.2 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFY02562.1 - 1.8e-12 46.1 0.1 0.0019 17.9 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFY02562.1 - 6.1e-12 45.8 5.1 3.7e-07 30.6 1.4 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KFY02562.1 - 2.2e-11 43.2 3.3 1.4e-05 24.5 0.2 2.4 1 1 2 3 3 3 3 TPR repeat TPR_7 PF13176.1 KFY02562.1 - 1.4e-10 40.1 2.3 0.0025 17.4 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KFY02562.1 - 4.6e-09 35.4 0.0 0.035 13.8 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFY02562.1 - 5.3e-09 35.9 1.3 0.065 13.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat PPR PF01535.15 KFY02562.1 - 1.2e-08 34.3 0.1 0.08 12.9 0.0 3.1 3 0 0 3 3 3 2 PPR repeat TPR_20 PF14561.1 KFY02562.1 - 1.3e-08 34.7 4.2 0.0035 17.4 0.1 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFY02562.1 - 1.4e-08 34.9 3.9 0.00019 21.7 0.4 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFY02562.1 - 1.7e-08 33.6 0.1 0.056 13.0 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 KFY02562.1 - 1.5e-07 31.4 0.2 0.0054 16.8 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR_1 PF12854.2 KFY02562.1 - 9.5e-06 24.9 4.6 0.59 9.6 0.1 3.2 3 0 0 3 3 3 2 PPR repeat TPR_4 PF07721.9 KFY02562.1 - 4e-05 23.6 12.2 0.035 14.5 1.4 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_5 PF12688.2 KFY02562.1 - 0.00011 22.2 2.9 0.00093 19.2 0.8 2.1 1 1 1 2 2 2 1 Tetratrico peptide repeat PPR_2 PF13041.1 KFY02562.1 - 0.00021 21.2 0.1 4.2 7.4 0.0 3.1 3 0 0 3 3 3 0 PPR repeat family Fis1_TPR_N PF14852.1 KFY02562.1 - 0.00027 20.1 3.7 3 7.1 0.1 3.2 3 0 0 3 3 3 1 Fis1 N-terminal tetratricopeptide repeat TPR_17 PF13431.1 KFY02562.1 - 0.00049 20.0 0.1 2 8.8 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat WbqC PF08889.6 KFY02562.1 - 0.0015 17.9 0.0 0.17 11.3 0.0 2.0 1 1 1 2 2 2 2 WbqC-like protein family Vps39_1 PF10366.4 KFY02562.1 - 0.0017 18.3 0.5 1.9 8.5 0.1 2.8 1 1 2 3 3 3 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.15 KFY02562.1 - 0.0051 16.4 0.2 2.6 7.6 0.0 2.8 3 0 0 3 3 3 1 Region in Clathrin and VPS PPR_3 PF13812.1 KFY02562.1 - 0.0085 16.3 0.2 5.8 7.4 0.0 3.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain ApoLp-III PF07464.6 KFY02562.1 - 0.0086 16.1 4.9 1.1 9.2 0.0 2.8 1 1 2 3 3 3 2 Apolipophorin-III precursor (apoLp-III) SPOB_a PF14689.1 KFY02562.1 - 0.011 15.3 2.5 12 5.5 0.0 3.1 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain Stk19 PF10494.4 KFY02562.1 - 0.013 14.8 0.3 2.4 7.4 0.1 2.0 1 1 1 2 2 2 0 Serine-threonine protein kinase 19 ATP13 PF12921.2 KFY02562.1 - 0.014 14.7 0.0 3.9 6.8 0.0 2.4 1 1 1 2 2 2 0 Mitochondrial ATPase expression PhnJ PF06007.6 KFY02562.1 - 0.022 13.5 0.0 9 4.9 0.0 2.8 1 1 2 3 3 3 0 Phosphonate metabolism protein PhnJ H-kinase_dim PF02895.9 KFY02562.1 - 0.024 14.9 1.0 3.6 8.0 0.1 2.2 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain PilO PF04350.8 KFY02562.1 - 0.025 14.4 0.1 1.6 8.5 0.0 2.6 1 1 2 3 3 3 0 Pilus assembly protein, PilO Plant_NMP1 PF06694.6 KFY02562.1 - 0.034 13.0 0.1 0.73 8.7 0.0 2.1 1 1 1 2 2 2 0 Plant nuclear matrix protein 1 (NMP1) MT PF12777.2 KFY02562.1 - 0.041 12.6 1.8 0.76 8.4 0.7 2.6 1 1 1 2 2 2 0 Microtubule-binding stalk of dynein motor TPR_21 PF09976.4 KFY02562.1 - 0.048 13.6 6.1 0.43 10.5 4.3 2.3 1 1 0 1 1 1 0 Tetratricopeptide repeat MRVI1 PF05781.7 KFY02562.1 - 0.072 11.4 3.6 0.17 10.2 2.5 1.5 1 1 0 1 1 1 0 MRVI1 protein UPF0052 PF01933.13 KFY02562.1 - 0.074 12.3 0.3 0.69 9.1 0.2 1.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0052 Aida_N PF08910.5 KFY02562.1 - 0.077 13.2 2.7 6.8 6.9 0.0 2.9 1 1 2 3 3 3 0 Aida N-terminus UBA PF00627.26 KFY02562.1 - 0.087 12.6 2.4 13 5.8 0.1 3.0 3 0 0 3 3 3 0 UBA/TS-N domain SNAP PF14938.1 KFY02562.1 - 0.1 11.7 0.7 0.14 11.3 0.5 1.3 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP NT5C PF06941.7 KFY02562.1 - 0.19 11.2 0.7 18 4.7 0.1 2.6 1 1 1 2 2 2 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) ATG16 PF08614.6 KFY02562.1 - 0.2 11.4 2.2 4.2 7.1 0.2 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FliJ PF02050.11 KFY02562.1 - 0.32 11.0 4.5 1.8 8.6 1.0 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein Patatin PF01734.17 KFY02563.1 - 9.8e-16 58.2 0.0 2.8e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase zf-C3HC4 PF00097.20 KFY02563.1 - 0.031 13.9 8.8 0.1 12.2 6.1 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFY02563.1 - 0.37 10.5 10.4 1.3 8.8 7.2 2.0 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KFY02563.1 - 0.56 9.9 13.8 0.019 14.5 5.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFY02563.1 - 1.8 8.5 9.5 5.7 6.8 6.6 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DnaJ PF00226.26 KFY02564.1 - 1.2e-17 63.4 0.4 3.2e-17 61.9 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain AbiH PF14253.1 KFY02567.1 - 0.11 12.0 0.3 0.17 11.4 0.2 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Phage_GP20 PF06810.6 KFY02568.1 - 0.0011 18.4 1.2 0.0018 17.7 0.8 1.3 1 0 0 1 1 1 1 Phage minor structural protein GP20 Myosin_tail_1 PF01576.14 KFY02568.1 - 0.0013 16.6 3.5 0.0016 16.2 2.4 1.1 1 0 0 1 1 1 1 Myosin tail STAT_alpha PF01017.15 KFY02568.1 - 0.0016 18.1 3.0 0.0025 17.5 2.1 1.3 1 0 0 1 1 1 1 STAT protein, all-alpha domain AAA_27 PF13514.1 KFY02568.1 - 0.003 15.3 2.3 0.0043 14.8 1.6 1.2 1 0 0 1 1 1 1 AAA domain Reo_sigmaC PF04582.7 KFY02568.1 - 0.013 14.6 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF641 PF04859.7 KFY02568.1 - 0.041 13.6 0.1 0.084 12.6 0.1 1.6 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Pepsin-I3 PF06394.8 KFY02568.1 - 0.064 12.9 1.9 0.082 12.5 0.1 2.0 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain IFT20 PF14931.1 KFY02568.1 - 0.094 12.6 1.8 0.085 12.7 0.3 1.7 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 IncA PF04156.9 KFY02568.1 - 0.2 11.1 1.6 0.39 10.2 1.1 1.4 1 1 0 1 1 1 0 IncA protein ADIP PF11559.3 KFY02568.1 - 0.33 10.8 3.3 0.54 10.1 2.3 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding AF0941-like PF14591.1 KFY02568.1 - 0.36 10.9 2.3 2.3 8.2 0.1 2.2 1 1 1 2 2 2 0 AF0941-like DUF724 PF05266.9 KFY02568.1 - 1.8 8.1 5.6 2.9 7.4 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ALIX_LYPXL_bnd PF13949.1 KFY02569.1 - 0.001 18.1 2.7 0.001 18.1 1.9 1.9 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DUF3450 PF11932.3 KFY02569.1 - 0.0022 17.2 10.3 0.0051 16.1 1.3 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF3450) bZIP_1 PF00170.16 KFY02569.1 - 0.0024 17.7 10.8 0.26 11.2 0.7 3.4 3 0 0 3 3 3 2 bZIP transcription factor TMF_DNA_bd PF12329.3 KFY02569.1 - 0.015 15.1 0.2 0.015 15.1 0.2 3.2 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Microtub_assoc PF07989.6 KFY02569.1 - 0.025 14.4 5.6 2.4 8.0 0.0 3.1 3 0 0 3 3 3 0 Microtubule associated Sipho_Gp157 PF05565.6 KFY02569.1 - 0.026 14.1 0.5 1.1 8.7 0.0 2.6 2 0 0 2 2 2 0 Siphovirus Gp157 CaMKII_AD PF08332.5 KFY02569.1 - 0.06 13.2 0.4 1.6 8.6 0.1 2.4 2 0 0 2 2 2 0 Calcium/calmodulin dependent protein kinase II Association CALCOCO1 PF07888.6 KFY02569.1 - 0.11 10.7 9.0 0.0097 14.2 2.3 1.8 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Prefoldin_2 PF01920.15 KFY02569.1 - 0.12 12.0 8.3 1.4 8.7 0.1 3.5 3 1 0 3 3 3 0 Prefoldin subunit DUF641 PF04859.7 KFY02569.1 - 0.21 11.3 3.1 1.2 8.9 0.5 2.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Tnp_P_element PF12017.3 KFY02569.1 - 0.22 10.7 4.1 1.1 8.4 0.1 2.6 3 0 0 3 3 3 0 Transposase protein GAS PF13851.1 KFY02569.1 - 0.27 10.4 13.5 0.29 10.2 0.3 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding TBPIP PF07106.8 KFY02569.1 - 0.28 10.7 6.8 0.27 10.7 0.4 2.8 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CCDC155 PF14662.1 KFY02569.1 - 1.2 8.7 13.2 0.3 10.6 1.2 3.0 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 ERM PF00769.14 KFY02569.1 - 1.3 8.4 17.2 2.5 7.5 0.8 2.8 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Mto2_bdg PF12808.2 KFY02569.1 - 1.4 9.1 13.8 0.15 12.1 0.4 4.3 3 1 1 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region YkuI_C PF10388.4 KFY02569.1 - 2.1 8.0 5.6 0.57 9.8 0.3 2.2 1 1 1 2 2 2 0 EAL-domain associated signalling protein domain ADIP PF11559.3 KFY02569.1 - 7.9 6.3 13.8 1.9 8.3 2.5 3.0 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Chitin_bind_1 PF00187.14 KFY02571.1 - 3.5e-06 26.9 14.8 1.2e-05 25.1 10.3 2.0 1 1 0 1 1 1 1 Chitin recognition protein Peptidase_S41 PF03572.13 KFY02571.1 - 0.062 12.7 1.9 0.34 10.3 0.1 2.2 2 0 0 2 2 2 0 Peptidase family S41 CDK2AP PF09806.4 KFY02571.1 - 1.1 9.4 9.5 3.3 7.9 2.8 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Glyco_hydro_18 PF00704.23 KFY02572.1 - 5.3e-75 252.9 0.3 6.3e-75 252.7 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 TPR_10 PF13374.1 KFY02573.1 - 6.7e-60 197.4 0.4 1.4e-11 43.8 0.0 7.0 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.1 KFY02573.1 - 1.8e-56 187.9 4.1 1.3e-14 53.9 0.0 4.6 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 KFY02573.1 - 1.3e-12 47.9 0.0 0.00018 22.1 0.0 4.1 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 KFY02573.1 - 1.9e-10 40.0 0.6 0.13 12.5 0.0 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFY02573.1 - 5.6e-09 35.5 0.1 0.0029 17.2 0.0 3.7 4 0 0 4 4 4 2 TPR repeat TPR_7 PF13176.1 KFY02573.1 - 1.5e-08 33.7 0.2 0.16 11.8 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFY02573.1 - 1.6e-07 30.6 0.0 0.23 11.1 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFY02573.1 - 2.6e-07 30.0 0.1 3.7 7.7 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFY02573.1 - 1.5e-06 27.5 0.5 1.1 9.2 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFY02573.1 - 0.00012 22.3 4.2 0.95 9.8 0.1 3.7 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_5 PF12688.2 KFY02573.1 - 0.00028 20.9 6.8 0.042 13.8 0.1 4.0 1 1 3 5 5 5 1 Tetratrico peptide repeat DUF956 PF06115.6 KFY02573.1 - 0.00045 19.8 0.6 0.67 9.5 0.0 4.0 2 2 3 5 5 5 1 Domain of unknown function (DUF956) A2M PF00207.17 KFY02573.1 - 0.0016 17.9 1.5 7.4 6.2 0.0 4.3 1 1 3 4 4 4 0 Alpha-2-macroglobulin family TPR_14 PF13428.1 KFY02573.1 - 0.0017 18.8 3.3 14 6.6 0.0 4.9 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFY02573.1 - 0.0053 17.0 0.0 3.4 8.3 0.0 4.7 6 0 0 6 6 5 1 Tetratricopeptide repeat ArsR PF09824.4 KFY02573.1 - 0.0057 15.9 2.5 3.3 6.9 0.3 3.1 1 1 1 3 3 3 1 ArsR transcriptional regulator GP40 PF11025.3 KFY02573.1 - 0.012 15.2 3.0 2.2 7.8 0.1 3.3 1 1 2 3 3 3 0 Glycoprotein GP40 of Cryptosporidium PA28_alpha PF02251.13 KFY02573.1 - 0.013 15.6 0.2 3.4 7.8 0.1 3.2 2 1 1 3 3 3 0 Proteasome activator pa28 alpha subunit TPR_20 PF14561.1 KFY02573.1 - 0.037 14.1 6.1 0.3 11.2 0.2 3.6 2 2 2 4 4 4 0 Tetratricopeptide repeat AnfG_VnfG PF03139.10 KFY02573.1 - 0.056 13.2 0.7 8.3 6.2 0.0 3.1 2 1 1 3 3 3 0 Vanadium/alternative nitrogenase delta subunit Corona_S2 PF01601.11 KFY02573.1 - 0.09 10.8 15.8 0.26 9.3 3.2 2.8 1 1 2 3 3 3 0 Coronavirus S2 glycoprotein UbiD PF01977.11 KFY02573.1 - 0.11 10.8 1.0 0.12 10.8 0.1 1.4 2 0 0 2 2 2 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase CaMKII_AD PF08332.5 KFY02573.1 - 0.15 11.9 1.3 2.9 7.8 0.1 2.6 2 1 0 2 2 2 0 Calcium/calmodulin dependent protein kinase II Association Rab5-bind PF09311.6 KFY02573.1 - 0.19 11.6 11.2 4.1 7.2 0.8 3.3 2 1 1 3 3 3 0 Rabaptin-like protein DUF3897 PF13036.1 KFY02573.1 - 0.25 10.9 8.6 1.1 8.7 0.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3897) F-box-like PF12937.2 KFY02574.1 - 4.7e-05 23.0 0.0 0.00011 21.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFY02574.1 - 0.015 14.9 0.0 0.05 13.2 0.0 1.9 1 0 0 1 1 1 0 F-box domain SRF-TF PF00319.13 KFY02575.1 - 4.2e-05 22.6 0.0 5e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) PPE PF00823.14 KFY02577.1 - 0.15 11.8 0.3 0.21 11.3 0.2 1.2 1 0 0 1 1 1 0 PPE family CRC_subunit PF08624.5 KFY02582.1 - 2.8e-54 182.7 0.0 4e-54 182.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit RNB PF00773.14 KFY02583.1 - 2.7e-93 312.8 0.4 5.1e-93 311.9 0.3 1.5 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 KFY02583.1 - 5.8e-09 36.1 0.2 4e-08 33.4 0.0 2.5 2 1 0 2 2 2 1 PIN domain HC2 PF07382.6 KFY02584.1 - 0.04 13.7 0.1 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 cobW PF02492.14 KFY02585.1 - 2.6e-10 40.0 0.0 3.1e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 KFY02585.1 - 0.0018 18.6 0.0 0.0022 18.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFY02585.1 - 0.026 13.9 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFY02585.1 - 0.032 13.8 0.0 0.038 13.6 0.0 1.1 1 0 0 1 1 1 0 NACHT domain TMEM51 PF15345.1 KFY02585.1 - 0.034 13.8 0.0 0.04 13.6 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 IstB_IS21 PF01695.12 KFY02585.1 - 0.043 13.2 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein ResIII PF04851.10 KFY02585.1 - 0.045 13.5 0.0 0.045 13.5 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KFY02585.1 - 0.056 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_21 PF13304.1 KFY02585.1 - 0.06 13.2 0.0 0.073 13.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 KFY02585.1 - 0.086 11.5 0.0 0.098 11.3 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus ArgK PF03308.11 KFY02585.1 - 0.1 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 ArgK protein PhoH PF02562.11 KFY02585.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.1 KFY02585.1 - 0.14 11.6 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dyp_perox PF04261.7 KFY02587.1 - 1.9e-91 306.1 0.0 2.1e-91 305.9 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family Glyco_hydro_61 PF03443.9 KFY02588.1 - 1.4e-79 266.9 0.0 2.4e-79 266.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SH3_3 PF08239.6 KFY02589.1 - 0.0089 16.1 0.1 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial SH3 domain Amidohydro_1 PF01979.15 KFY02590.1 - 2.7e-33 116.0 0.0 4.1e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KFY02590.1 - 0.00061 19.1 2.7 0.014 14.5 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase family A_deaminase PF00962.17 KFY02590.1 - 0.00099 18.1 0.0 0.0015 17.4 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_4 PF13147.1 KFY02590.1 - 0.0019 18.2 0.6 0.77 9.7 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 KFY02590.1 - 0.0033 17.2 0.0 0.011 15.5 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase Sugar_tr PF00083.19 KFY02591.1 - 1.2e-89 300.9 27.2 1.5e-89 300.6 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY02591.1 - 1.5e-25 89.6 64.7 1.9e-21 76.2 28.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFY02591.1 - 0.00049 18.4 3.9 0.00049 18.4 2.7 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 KFY02591.1 - 0.0012 16.9 6.8 0.0053 14.8 1.1 2.3 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 KFY02591.1 - 0.089 10.8 11.6 0.22 9.5 1.3 2.3 2 0 0 2 2 2 0 Transmembrane secretion effector Glyco_hyd_65N_2 PF14498.1 KFY02592.1 - 0.017 14.7 0.0 0.055 13.1 0.0 1.8 1 1 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Meth_synt_2 PF01717.13 KFY02593.1 - 2.8e-146 486.6 0.0 1.3e-139 464.6 0.0 3.3 3 1 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KFY02593.1 - 1.4e-123 412.0 0.4 2.6e-111 371.8 0.1 3.2 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 KFY02593.1 - 0.0048 15.8 0.1 1 8.1 0.0 3.0 4 0 0 4 4 4 2 Uroporphyrinogen decarboxylase (URO-D) TSSC4 PF15264.1 KFY02593.1 - 0.057 13.8 0.3 0.14 12.6 0.0 1.7 2 0 0 2 2 2 0 Tumour suppressing sub-chromosomal transferable candidate 4 Alpha_L_fucos PF01120.12 KFY02593.1 - 0.062 12.1 0.0 0.15 10.9 0.0 1.6 1 0 0 1 1 1 0 Alpha-L-fucosidase SHOCT PF09851.4 KFY02593.1 - 0.078 12.4 0.2 0.078 12.4 0.2 2.8 3 0 0 3 3 3 0 Short C-terminal domain T_cell_tran_alt PF15128.1 KFY02595.1 - 0.2 11.1 0.6 0.43 10.0 0.1 1.9 2 0 0 2 2 2 0 T-cell leukemia translocation-altered Sugar_tr PF00083.19 KFY02601.1 - 2.9e-32 111.8 26.8 4.8e-32 111.1 18.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Phosphodiest PF01663.17 KFY02601.1 - 3.9e-29 102.1 0.0 6e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.11 KFY02601.1 - 1.3e-15 57.0 48.5 1e-14 54.0 17.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily HD PF01966.17 KFY02601.1 - 3.4e-07 30.3 0.1 6.5e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 HD domain HDOD PF08668.7 KFY02601.1 - 0.061 12.5 0.1 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 HDOD domain HD_4 PF13328.1 KFY02601.1 - 0.067 12.9 0.0 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 HD domain HI0933_like PF03486.9 KFY02603.1 - 0.078 11.4 0.1 0.094 11.1 0.1 1.0 1 0 0 1 1 1 0 HI0933-like protein Cu-oxidase_3 PF07732.10 KFY02604.1 - 2.5e-12 46.5 0.0 9e-08 31.8 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFY02604.1 - 7.6e-07 28.7 0.0 0.071 12.6 0.0 3.1 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 KFY02604.1 - 8.3e-05 22.5 0.0 0.00018 21.4 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cupredoxin_1 PF13473.1 KFY02604.1 - 0.013 15.3 0.0 0.56 10.1 0.0 2.4 2 0 0 2 2 2 0 Cupredoxin-like domain Copper-bind PF00127.15 KFY02604.1 - 0.1 12.8 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family GCS2 PF04107.8 KFY02605.1 - 0.041 12.9 0.4 0.047 12.8 0.3 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) Mre11_DNA_bind PF04152.9 KFY02605.1 - 0.17 11.7 1.6 0.23 11.3 1.1 1.3 1 0 0 1 1 1 0 Mre11 DNA-binding presumed domain YbaB_DNA_bd PF02575.11 KFY02605.1 - 0.34 10.8 3.8 0.85 9.5 2.2 2.0 1 1 0 1 1 1 0 YbaB/EbfC DNA-binding family SGL PF08450.7 KFY02606.1 - 3.4e-06 26.6 0.0 5.2e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Abhydrolase_3 PF07859.8 KFY02607.1 - 2e-35 122.2 0.1 3.5e-35 121.4 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFY02607.1 - 1.1e-06 28.4 0.0 1.7e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KFY02607.1 - 3e-06 26.2 0.0 5.4e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.16 KFY02607.1 - 0.00061 19.0 0.1 0.0012 18.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 KFY02607.1 - 0.0015 17.8 0.1 0.042 13.1 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.7 KFY02607.1 - 0.0016 16.9 0.0 0.0027 16.2 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 KFY02607.1 - 0.0078 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KFY02607.1 - 0.01 15.7 2.2 0.025 14.4 1.5 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 KFY02607.1 - 0.029 13.7 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) BNR PF02012.15 KFY02608.1 - 1.6e-11 42.2 45.0 0.16 11.8 0.0 10.7 10 0 0 10 10 10 9 BNR/Asp-box repeat Glyco_hydro_2_N PF02837.13 KFY02609.1 - 1.9e-33 115.4 0.0 4.8e-33 114.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KFY02609.1 - 4.9e-28 97.8 0.0 1.8e-27 96.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KFY02609.1 - 2.3e-12 47.3 0.3 4.8e-12 46.2 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 KFY02609.1 - 0.0034 17.6 0.0 0.019 15.2 0.0 2.2 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain ADH_N PF08240.7 KFY02613.1 - 4.4e-28 97.2 0.8 7.9e-28 96.3 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFY02613.1 - 1.9e-19 69.4 0.2 3.5e-19 68.6 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 KFY02613.1 - 0.015 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TP_methylase PF00590.15 KFY02613.1 - 0.096 12.3 0.7 0.74 9.4 0.1 2.0 2 0 0 2 2 2 0 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_8 PF13450.1 KFY02613.1 - 0.13 12.3 0.2 0.31 11.1 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain adh_short PF00106.20 KFY02615.1 - 1.4e-28 99.9 0.2 2.5e-28 99.1 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFY02615.1 - 6.5e-17 62.1 0.0 8.5e-17 61.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFY02615.1 - 1.3e-12 47.7 0.3 2.3e-12 46.9 0.2 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KFY02615.1 - 1.2e-05 24.8 0.0 2.3e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KFY02615.1 - 0.0069 16.1 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 KFY02615.1 - 0.019 14.1 0.1 0.031 13.5 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family Fungal_trans PF04082.13 KFY02616.1 - 2.3e-15 56.1 0.0 5.2e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY02616.1 - 4.3e-07 29.7 6.9 7.8e-07 28.8 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.14 KFY02617.1 - 1.8e-55 186.8 0.0 2.4e-55 186.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFY02617.1 - 1.6e-21 76.1 0.0 1.9e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFY02617.1 - 0.0017 18.2 0.0 0.0036 17.1 0.0 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KFY02617.1 - 0.037 14.4 0.0 0.077 13.4 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FMN_dh PF01070.13 KFY02618.1 - 1.5e-103 346.4 0.0 1.9e-103 346.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KFY02618.1 - 1.6e-20 72.6 0.0 3.1e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 KFY02618.1 - 2.2e-05 23.4 0.0 0.00083 18.3 0.0 2.8 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KFY02618.1 - 8.5e-05 21.6 0.0 0.00014 20.8 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase ATP11 PF06644.6 KFY02618.1 - 0.081 12.3 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 ATP11 protein Aldo_ket_red PF00248.16 KFY02619.1 - 1.4e-47 161.9 0.0 1.7e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family RNA_pol_Rpb8 PF03870.10 KFY02627.1 - 3.6e-21 75.8 0.0 4.5e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb8 VirK PF06903.7 KFY02627.1 - 0.19 11.4 0.8 18 5.1 0.0 2.2 1 1 1 2 2 2 0 VirK protein PAXNEB PF05625.6 KFY02628.1 - 1.1e-104 350.2 0.0 1.2e-104 350.0 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein zf-C3HC4_3 PF13920.1 KFY02629.1 - 1e-07 31.5 12.0 1.7e-07 30.7 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFY02629.1 - 4 7.5 16.0 7.6 6.6 11.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) tRNA_int_endo PF01974.12 KFY02630.1 - 1.8e-13 50.0 0.0 5.5e-13 48.5 0.0 1.7 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain RNase_PH PF01138.16 KFY02631.1 - 4.6e-26 91.6 0.0 8.9e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Anp1 PF03452.9 KFY02632.1 - 3.9e-121 403.3 0.0 5.3e-121 402.8 0.0 1.2 1 0 0 1 1 1 1 Anp1 Sec7 PF01369.15 KFY02633.1 - 3.4e-59 199.7 0.0 5.4e-59 199.0 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KFY02633.1 - 2.8e-19 69.1 0.3 2e-11 43.6 0.2 3.0 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Abhydrolase_6 PF12697.2 KFY02634.1 - 5.3e-16 59.1 3.2 6.2e-16 58.9 2.2 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFY02634.1 - 4.6e-06 26.4 0.2 5.4e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 KFY02634.1 - 0.1 12.0 0.2 0.22 10.9 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase DsbC_N PF10411.4 KFY02634.1 - 0.14 11.4 0.0 0.3 10.3 0.0 1.5 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus FAD_binding_2 PF00890.19 KFY02635.1 - 6.8e-90 301.8 0.1 7.7e-90 301.7 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KFY02635.1 - 1.1e-07 31.7 0.5 5.3e-07 29.5 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFY02635.1 - 6.6e-06 26.1 0.0 0.0025 17.7 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFY02635.1 - 1.7e-05 24.0 0.2 7e-05 22.0 0.0 2.1 3 0 0 3 3 3 1 Thi4 family DAO PF01266.19 KFY02635.1 - 2.7e-05 23.2 1.1 0.00012 21.1 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KFY02635.1 - 3.5e-05 23.0 0.0 5.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KFY02635.1 - 6.4e-05 22.7 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding GIDA PF01134.17 KFY02635.1 - 0.00014 20.8 2.1 0.00022 20.2 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 KFY02635.1 - 0.00032 19.3 0.7 0.003 16.1 0.0 2.4 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 KFY02635.1 - 0.0012 18.0 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KFY02635.1 - 0.0036 17.4 0.0 0.0085 16.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFY02635.1 - 0.015 14.2 0.1 0.025 13.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein TPR_14 PF13428.1 KFY02636.1 - 1.4e-11 43.9 6.1 0.95 10.2 0.0 9.5 11 0 0 11 11 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFY02636.1 - 2.7e-11 43.2 0.1 2 8.4 0.0 7.2 6 1 0 7 7 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFY02636.1 - 9.8e-08 31.5 0.8 0.62 9.7 0.0 6.8 8 0 0 8 8 7 1 TPR repeat TPR_15 PF13429.1 KFY02636.1 - 5e-07 29.0 1.8 0.00018 20.6 0.2 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFY02636.1 - 3.4e-06 27.5 3.4 0.004 17.7 0.0 5.1 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KFY02636.1 - 6.7e-06 26.3 0.1 0.043 14.1 0.0 5.6 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFY02636.1 - 8.6e-05 22.1 12.0 1.2 9.2 0.0 6.5 8 0 0 8 8 5 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 KFY02636.1 - 0.00015 21.5 10.4 0.67 9.7 0.1 6.3 7 0 0 7 7 7 1 Mad3/BUB1 homology region 1 Suf PF05843.9 KFY02636.1 - 0.00034 20.4 9.4 0.27 10.9 0.1 4.6 5 0 0 5 5 5 2 Suppressor of forked protein (Suf) TPR_8 PF13181.1 KFY02636.1 - 0.00049 19.6 2.4 1.3 8.9 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat RPN7 PF10602.4 KFY02636.1 - 0.013 14.8 0.0 0.43 9.9 0.0 3.1 3 1 0 3 3 3 0 26S proteasome subunit RPN7 TPR_17 PF13431.1 KFY02636.1 - 0.013 15.6 1.7 0.67 10.2 0.0 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KFY02636.1 - 0.021 14.7 2.9 22 5.1 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat NRDE-2 PF08424.5 KFY02636.1 - 0.021 13.7 10.9 0.16 10.7 0.8 5.3 2 2 1 3 3 3 0 NRDE-2, necessary for RNA interference TPR_6 PF13174.1 KFY02636.1 - 0.075 13.5 2.3 11 6.7 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat ATP-synt_D PF01813.12 KFY02637.1 - 3.3e-65 219.3 2.2 4.2e-65 218.9 1.5 1.1 1 0 0 1 1 1 1 ATP synthase subunit D SYCE1 PF15233.1 KFY02637.1 - 0.54 10.1 3.2 0.4 10.6 0.5 2.0 2 1 0 2 2 2 0 Synaptonemal complex central element protein 1 Nup54 PF13874.1 KFY02637.1 - 0.71 9.5 3.5 3.8 7.1 0.2 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Prefoldin PF02996.12 KFY02637.1 - 1.4 8.6 4.9 2.3 7.8 0.0 3.0 2 1 2 4 4 4 0 Prefoldin subunit Viral_P18 PF04521.8 KFY02637.1 - 1.6 8.1 5.9 10 5.5 0.5 2.3 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein RRM_1 PF00076.17 KFY02638.1 - 4.7e-25 87.0 1.1 3.9e-13 48.8 0.2 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY02638.1 - 6.3e-17 61.3 0.2 4.5e-08 32.9 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFY02638.1 - 3.8e-14 52.2 1.5 2.5e-10 40.0 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF45 PF01863.12 KFY02638.1 - 0.18 11.5 1.3 0.25 11.0 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF45 Syja_N PF02383.13 KFY02639.1 - 4.2e-85 285.3 0.0 1.7e-83 280.0 0.0 2.5 1 1 0 1 1 1 1 SacI homology domain DUF2454 PF10521.4 KFY02640.1 - 9.7e-60 201.9 0.2 1.5e-59 201.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) HEAT PF02985.17 KFY02640.1 - 0.041 13.9 0.0 0.19 11.9 0.0 2.3 1 0 0 1 1 1 0 HEAT repeat DUF2435 PF10363.4 KFY02640.1 - 0.09 12.6 0.2 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) PolyA_pol PF01743.15 KFY02641.1 - 6.7e-25 87.7 0.1 1.3e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 KFY02641.1 - 2.3e-05 23.8 0.0 5.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A TRAPPC-Trs85 PF12739.2 KFY02642.1 - 1.2e-116 389.7 0.0 1.7e-116 389.3 0.0 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Snf7 PF03357.16 KFY02643.1 - 6.7e-19 67.8 12.9 1.4e-18 66.8 8.9 1.7 1 1 0 1 1 1 1 Snf7 CK2S PF15011.1 KFY02643.1 - 0.054 13.2 6.3 1 9.1 0.2 3.2 2 1 1 3 3 3 0 Casein Kinase 2 substrate Baculo_PEP_C PF04513.7 KFY02643.1 - 0.071 12.9 2.2 4.3 7.1 0.3 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF932 PF06067.6 KFY02643.1 - 0.17 11.1 6.0 2.9 7.1 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF932) MutS_III PF05192.13 KFY02643.1 - 1.5 8.5 6.3 5.5 6.7 4.2 2.0 1 1 0 1 1 1 0 MutS domain III RNase_H2_suC PF08615.6 KFY02644.1 - 3.1e-22 78.9 0.0 5.8e-22 78.0 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) zf-C3HC4_3 PF13920.1 KFY02644.1 - 3.1e-07 29.9 13.5 2.6e-06 27.0 7.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFY02644.1 - 5.1e-07 29.2 12.5 5.1e-07 29.2 8.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFY02644.1 - 9.8e-07 28.7 13.0 9.8e-07 28.7 9.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFY02644.1 - 1.1e-06 28.2 15.4 1.3e-06 28.0 8.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 KFY02644.1 - 2.9e-06 26.9 3.7 2.9e-06 26.9 2.5 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KFY02644.1 - 5.1e-06 26.0 7.8 5.1e-06 26.0 5.4 2.6 2 0 0 2 2 2 1 RING-type zinc-finger U-box PF04564.10 KFY02644.1 - 8.4e-06 25.6 0.0 1.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-C3HC4_4 PF15227.1 KFY02644.1 - 2e-05 24.3 15.6 5e-05 23.0 8.5 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KFY02644.1 - 4e-05 23.3 16.5 5.5e-05 22.9 8.6 2.4 2 0 0 2 2 2 1 Ring finger domain SAP PF02037.22 KFY02644.1 - 7.8e-05 22.0 0.0 0.00017 21.0 0.0 1.6 1 0 0 1 1 1 1 SAP domain Stonin2_N PF12016.3 KFY02644.1 - 0.0015 17.7 0.1 0.0029 16.7 0.1 1.4 1 0 0 1 1 1 1 Stonin 2 zf-rbx1 PF12678.2 KFY02644.1 - 0.0041 17.2 7.2 0.0058 16.7 3.0 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_4 PF14570.1 KFY02644.1 - 0.0045 16.5 8.3 0.0045 16.5 5.7 2.3 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain DUF1455 PF07306.6 KFY02644.1 - 0.058 13.4 0.3 3.1 7.8 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1455) Mob_synth_C PF06463.8 KFY02644.1 - 0.25 11.0 3.1 0.7 9.5 2.1 1.7 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C RNase_T PF00929.19 KFY02645.1 - 3e-27 95.9 0.0 4.3e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 KFY02645.1 - 2.4e-05 23.8 0.0 7.4e-05 22.2 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease MOZ_SAS PF01853.13 KFY02646.1 - 1.2e-84 282.2 0.2 1.7e-84 281.7 0.2 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 KFY02646.1 - 3.5e-18 65.0 0.0 1.4e-17 63.0 0.0 2.1 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 KFY02646.1 - 0.14 12.2 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF1237 PF06824.6 KFY02647.1 - 1.2e-177 590.7 0.0 1.4e-177 590.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) CDC27 PF09507.5 KFY02648.1 - 5.4e-81 273.0 15.1 6.7e-81 272.7 10.5 1.1 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 MCM PF00493.18 KFY02649.1 - 2.2e-136 454.0 0.6 3.5e-136 453.3 0.4 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KFY02649.1 - 5.8e-22 78.4 0.4 2.3e-21 76.5 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFY02649.1 - 7e-08 31.8 0.0 8.4e-07 28.3 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KFY02649.1 - 0.0013 18.2 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 KFY02649.1 - 0.0014 18.2 0.0 0.0033 17.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KFY02649.1 - 0.0067 16.1 0.0 0.018 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Aminotran_1_2 PF00155.16 KFY02650.1 - 1.9e-21 76.4 0.0 2.5e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KFY02650.1 - 0.0011 17.6 0.0 0.008 14.7 0.0 2.2 2 1 0 2 2 2 1 Alanine-glyoxylate amino-transferase ETC_C1_NDUFA4 PF04800.7 KFY02651.1 - 5.9e-37 125.5 1.0 5.9e-37 125.5 0.7 1.6 2 0 0 2 2 2 1 ETC complex I subunit conserved region F1F0-ATPsyn_F PF10791.4 KFY02652.1 - 5.2e-42 142.0 0.4 6.1e-42 141.7 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 KFY02652.1 - 0.00021 21.2 0.2 0.00029 20.8 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f NACHT PF05729.7 KFY02660.1 - 1.5e-06 28.0 0.0 2.8e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KFY02660.1 - 0.0018 18.4 0.0 0.007 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain IncA PF04156.9 KFY02660.1 - 0.0044 16.6 0.7 1.1 8.8 0.0 3.3 3 0 0 3 3 3 1 IncA protein AAA PF00004.24 KFY02660.1 - 0.031 14.4 1.2 0.9 9.7 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFY02660.1 - 0.036 14.0 0.1 0.14 12.1 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 KFY02660.1 - 0.1 13.4 0.7 1.4 9.7 0.0 3.0 3 1 0 3 3 3 0 AAA domain WD40 PF00400.27 KFY02662.1 - 6.2e-73 238.2 5.2 1.7e-11 43.5 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat NACHT PF05729.7 KFY02662.1 - 1.7e-11 44.0 0.4 3.2e-11 43.1 0.3 1.5 1 0 0 1 1 1 1 NACHT domain Nucleoporin_N PF08801.6 KFY02662.1 - 0.028 13.1 4.3 1.1 7.9 0.2 3.4 1 1 3 4 4 4 0 Nup133 N terminal like CobA_CobO_BtuR PF02572.10 KFY02662.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Zn_clus PF00172.13 KFY02668.1 - 1.5 8.8 15.4 2.1 8.3 10.6 1.2 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KFY02669.1 - 1.8e-25 89.8 0.1 2.4e-25 89.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFY02669.1 - 1.7e-23 83.6 0.1 2.2e-23 83.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFY02669.1 - 1.9e-08 34.1 0.1 2.9e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KFY02669.1 - 9.9e-05 21.8 0.0 0.00054 19.4 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 KFY02669.1 - 0.00022 20.5 0.0 0.0044 16.1 0.0 2.1 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KFY02669.1 - 0.00082 19.4 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFY02669.1 - 0.029 13.6 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 KFY02669.1 - 0.029 13.2 0.0 0.051 12.4 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain PAE PF03283.8 KFY02669.1 - 0.062 11.9 0.0 0.074 11.6 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase MFS_1 PF07690.11 KFY02670.1 - 1.3e-23 83.2 27.0 1.6e-23 82.9 18.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY02670.1 - 1.6e-09 36.8 28.3 2.9e-09 36.0 19.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter RRM_1 PF00076.17 KFY02671.1 - 3.8e-19 68.0 0.1 8.1e-19 67.0 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY02671.1 - 1.8e-14 53.4 0.1 4.1e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFY02671.1 - 2.1e-07 30.7 0.0 4.7e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myb_DNA-bind_6 PF13921.1 KFY02671.1 - 0.011 15.8 1.5 0.15 12.2 0.3 2.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain zf-C2H2_4 PF13894.1 KFY02671.1 - 0.059 13.7 15.2 1.5 9.3 0.1 5.3 4 0 0 4 4 4 0 C2H2-type zinc finger EF-hand_3 PF09069.6 KFY02672.1 - 0.09 12.8 0.0 0.098 12.7 0.0 1.1 1 0 0 1 1 1 0 EF-hand Glyco_hydro_cc PF11790.3 KFY02673.1 - 1e-66 224.8 0.1 1e-66 224.8 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core DUF3328 PF11807.3 KFY02674.1 - 2.9e-29 102.3 3.0 4.3e-29 101.7 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF1126 PF06565.7 KFY02675.1 - 0.0047 16.3 0.1 22 4.6 0.0 3.2 3 0 0 3 3 3 3 Repeat of unknown function (DUF1126) DUF4392 PF14336.1 KFY02675.1 - 0.0083 14.9 0.1 2.3 6.9 0.0 3.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4392) Spo7 PF03907.8 KFY02675.1 - 7.4 6.1 10.7 24 4.4 0.1 3.5 4 0 0 4 4 4 0 Spo7-like protein Amidoligase_2 PF12224.3 KFY02677.1 - 4.3e-29 101.8 0.0 6.2e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Putative amidoligase enzyme Gtr1_RagA PF04670.7 KFY02677.1 - 0.015 14.4 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MARVEL PF01284.18 KFY02678.1 - 2.6e-07 30.5 15.9 2.1e-06 27.6 7.4 2.0 1 1 1 2 2 2 2 Membrane-associating domain DUF4234 PF14018.1 KFY02678.1 - 0.013 15.2 0.7 0.013 15.2 0.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) VIT1 PF01988.14 KFY02678.1 - 0.03 13.7 2.3 0.021 14.3 0.6 1.4 1 1 1 2 2 2 0 VIT family CorA PF01544.13 KFY02678.1 - 0.11 11.5 0.8 0.18 10.8 0.6 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2207 PF09972.4 KFY02678.1 - 0.31 9.5 4.6 0.29 9.6 2.6 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) FA_desaturase PF00487.19 KFY02678.1 - 0.63 9.4 5.4 1.3 8.3 3.6 1.7 1 1 0 1 1 1 0 Fatty acid desaturase O-antigen_lig PF13425.1 KFY02678.1 - 1.5 8.8 8.9 0.36 10.7 2.5 2.3 1 1 2 3 3 3 0 O-antigen ligase like membrane protein DUF3816 PF12822.2 KFY02678.1 - 5.8 6.7 11.5 9.1 6.1 7.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3816) zf-U1 PF06220.7 KFY02679.1 - 0.00027 20.4 0.5 0.00054 19.4 0.3 1.5 1 0 0 1 1 1 1 U1 zinc finger Band_7 PF01145.20 KFY02680.1 - 9.4e-32 110.3 0.4 9.4e-32 110.3 0.3 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KFY02680.1 - 0.0019 17.7 0.0 0.0039 16.7 0.0 1.5 1 0 0 1 1 1 1 SPFH domain-Band 7 family Sec7_N PF12783.2 KFY02681.1 - 4.1e-39 133.7 0.4 4.1e-39 133.7 0.3 3.0 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KFY02681.1 - 0.00022 20.7 0.1 0.0079 15.6 0.0 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) UQ_con PF00179.21 KFY02682.1 - 1.5e-18 66.5 0.0 1.7e-18 66.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KFY02682.1 - 0.013 15.4 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 0 RWD domain Complex1_LYR_1 PF13232.1 KFY02683.1 - 2.9e-07 30.5 1.9 9.3e-07 28.9 0.0 2.4 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR PF05347.10 KFY02683.1 - 5e-07 29.4 0.0 5e-07 29.4 0.0 2.5 3 0 0 3 3 3 1 Complex 1 protein (LYR family) bZIP_1 PF00170.16 KFY02684.1 - 2.8e-05 23.9 0.7 9.1e-05 22.3 0.5 1.9 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 KFY02684.1 - 0.088 12.3 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Rcd1 PF04078.8 KFY02685.1 - 3.3e-131 435.9 3.9 3.9e-131 435.6 2.7 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like V-ATPase_H_N PF03224.9 KFY02685.1 - 0.075 12.1 2.9 4.8 6.1 1.8 2.9 1 1 0 1 1 1 0 V-ATPase subunit H Pkinase PF00069.20 KFY02686.1 - 1.3e-77 260.4 0.0 2.6e-77 259.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY02686.1 - 1.4e-38 132.4 0.1 1.2e-37 129.4 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 KFY02686.1 - 1e-17 63.3 0.1 1.7e-17 62.5 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 KFY02686.1 - 3.3e-05 23.0 0.0 6.3e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KFY02686.1 - 5.5e-05 22.2 0.0 0.00012 21.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like WaaY PF06176.6 KFY02686.1 - 0.0017 17.6 0.1 0.0031 16.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 KFY02686.1 - 0.0075 16.0 0.0 0.043 13.5 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KFY02686.1 - 0.0082 15.5 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL DUF1604 PF07713.8 KFY02687.1 - 2.9e-37 126.3 4.3 4.6e-37 125.6 0.6 3.1 4 0 0 4 4 4 1 Protein of unknown function (DUF1604) G-patch PF01585.18 KFY02687.1 - 2e-06 27.4 1.7 6.4e-06 25.8 1.1 1.9 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KFY02687.1 - 0.12 12.2 4.1 0.071 12.9 0.6 2.4 2 1 0 2 2 2 0 DExH-box splicing factor binding site Dioxygenase_C PF00775.16 KFY02692.1 - 1.3e-10 40.8 0.1 2e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Med2 PF11214.3 KFY02693.1 - 0.015 15.3 0.0 0.2 11.7 0.0 2.4 2 0 0 2 2 2 0 Mediator complex subunit 2 RRM_1 PF00076.17 KFY02694.1 - 4.3e-58 192.8 0.0 7.8e-20 70.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY02694.1 - 3e-44 148.8 0.0 8.8e-15 54.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFY02694.1 - 8.9e-31 105.5 0.0 6.6e-11 41.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFY02694.1 - 1.1e-06 28.2 0.1 0.0096 15.6 0.0 3.6 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 KFY02694.1 - 0.045 13.5 0.0 61 3.4 0.0 3.3 2 1 1 3 3 3 0 Nup53/35/40-type RNA recognition motif PIF1 PF05970.9 KFY02695.1 - 4.8e-58 196.8 0.2 6.5e-45 153.6 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 KFY02695.1 - 1.7e-17 63.6 0.0 3.3e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFY02695.1 - 4.2e-06 26.9 0.0 8.9e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFY02695.1 - 1.1e-05 25.0 0.2 3.5e-05 23.4 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 KFY02695.1 - 5.4e-05 21.1 0.1 0.00047 18.0 0.0 2.0 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.1 KFY02695.1 - 0.00012 22.1 0.1 0.0007 19.6 0.1 2.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 KFY02695.1 - 0.00038 19.7 0.0 0.00089 18.5 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein T2SE PF00437.15 KFY02695.1 - 0.003 16.5 0.2 0.0052 15.7 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.24 KFY02695.1 - 0.013 15.7 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 KFY02695.1 - 0.014 14.4 0.1 0.025 13.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 KFY02695.1 - 0.016 15.1 0.0 0.05 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KFY02695.1 - 0.018 14.5 0.0 0.055 13.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 KFY02695.1 - 0.033 13.7 0.1 3.1 7.2 0.0 2.6 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 KFY02695.1 - 0.035 14.2 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 RNA helicase TrwB_AAD_bind PF10412.4 KFY02695.1 - 0.06 11.9 0.0 0.12 10.9 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Sigma54_activ_2 PF14532.1 KFY02695.1 - 0.067 13.2 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 KFY02695.1 - 0.071 12.2 0.2 0.23 10.5 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KFY02695.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_7 PF12775.2 KFY02695.1 - 0.19 10.8 0.1 0.46 9.5 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region D3 zf-CCHC PF00098.18 KFY02695.1 - 1.8 8.6 5.7 3.4 7.7 4.0 1.5 1 0 0 1 1 1 0 Zinc knuckle p450 PF00067.17 KFY02696.1 - 4.9e-62 209.9 0.0 6.3e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 E1-E2_ATPase PF00122.15 KFY02697.1 - 1.2e-50 171.7 0.1 4e-50 170.0 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KFY02697.1 - 2.7e-35 122.7 0.0 5.3e-35 121.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KFY02697.1 - 1.8e-28 98.4 3.3 2.7e-09 37.0 0.1 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 KFY02697.1 - 8.6e-16 58.6 0.0 5e-15 56.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFY02697.1 - 0.00034 20.2 0.1 0.00057 19.5 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Patched PF02460.13 KFY02698.1 - 6.2e-72 242.7 14.6 6.2e-71 239.4 10.1 2.0 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 KFY02698.1 - 4.6e-52 175.5 6.5 4.6e-52 175.5 4.5 2.8 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 KFY02698.1 - 2.5e-05 23.1 6.9 2.5e-05 23.1 4.8 3.0 2 1 0 2 2 2 1 MMPL family PP_M1 PF03012.9 KFY02699.1 - 0.077 12.3 0.2 0.089 12.1 0.1 1.0 1 0 0 1 1 1 0 Phosphoprotein MelC1 PF06236.6 KFY02700.1 - 0.65 9.9 4.5 0.49 10.3 2.0 1.6 1 1 0 2 2 2 0 Tyrosinase co-factor MelC1 Complex1_30kDa PF00329.14 KFY02702.1 - 3.2e-37 126.8 0.1 4.9e-37 126.2 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_4 PF14570.1 KFY02703.1 - 3.5e-19 68.1 12.1 5.6e-19 67.4 8.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 KFY02703.1 - 5.1e-07 29.2 0.0 2.4e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 KFY02703.1 - 2.7e-06 26.9 6.8 4.8e-06 26.1 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_5 PF13893.1 KFY02703.1 - 0.00015 21.5 0.0 0.00036 20.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.7 KFY02703.1 - 0.00023 20.4 3.8 0.00023 20.4 2.6 3.0 2 0 0 2 2 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 KFY02703.1 - 0.00072 19.3 9.1 0.0012 18.5 6.3 1.4 1 0 0 1 1 1 1 Ring finger domain RRM_6 PF14259.1 KFY02703.1 - 0.0073 16.2 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 KFY02703.1 - 0.023 14.4 4.2 0.046 13.4 2.9 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Nup35_RRM_2 PF14605.1 KFY02703.1 - 0.026 14.2 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-C3HC4 PF00097.20 KFY02703.1 - 0.11 12.1 9.9 0.22 11.2 6.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 KFY02703.1 - 0.16 11.8 4.1 0.34 10.8 2.9 1.5 1 0 0 1 1 1 0 FYVE zinc finger SET_assoc PF11767.3 KFY02703.1 - 0.27 10.5 0.0 0.57 9.5 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated zf-RING_5 PF14634.1 KFY02703.1 - 0.44 10.3 10.4 0.76 9.5 7.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFY02703.1 - 0.47 10.5 10.5 0.87 9.6 7.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 KFY02703.1 - 1.7 8.4 7.4 0.3 10.8 2.3 1.9 2 0 0 2 2 1 0 Zinc-binding RING-finger FYVE_2 PF02318.11 KFY02703.1 - 1.9 8.4 13.9 0.014 15.3 2.7 2.7 3 1 0 3 3 3 0 FYVE-type zinc finger Prok-RING_4 PF14447.1 KFY02703.1 - 4.7 6.8 9.0 1.2 8.7 3.1 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 PNP_UDP_1 PF01048.15 KFY02704.1 - 7.4e-40 136.3 0.3 8.9e-40 136.1 0.2 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Med13_C PF06333.7 KFY02705.1 - 2.8e-26 92.0 0.0 3.1e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal Cpn60_TCP1 PF00118.19 KFY02707.1 - 1.1e-20 73.7 0.1 1.5e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 KFY02707.1 - 1.2e-12 47.5 9.8 2e-12 46.7 6.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger HEAT PF02985.17 KFY02707.1 - 0.24 11.6 0.3 0.98 9.6 0.0 2.2 2 0 0 2 2 2 0 HEAT repeat FYVE_2 PF02318.11 KFY02707.1 - 0.43 10.4 6.4 1 9.2 4.4 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Mpv17_PMP22 PF04117.7 KFY02708.1 - 1.9e-23 81.8 4.4 3.2e-23 81.1 3.0 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family TPP1 PF10341.4 KFY02708.1 - 4e-06 26.7 0.0 8.3e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD IF4E PF01652.13 KFY02709.1 - 3.7e-59 198.9 0.1 4.4e-59 198.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AMP-binding PF00501.23 KFY02710.1 - 2.4e-69 233.7 0.0 2.9e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFY02710.1 - 2.5e-15 57.1 0.1 5.7e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BolA PF01722.13 KFY02711.1 - 4.3e-29 100.2 2.2 5.2e-29 100.0 1.5 1.1 1 0 0 1 1 1 1 BolA-like protein RPA_C PF08784.6 KFY02711.1 - 0.064 13.6 0.1 0.078 13.3 0.0 1.3 1 1 0 1 1 1 0 Replication protein A C terminal bact-PGI_C PF10432.4 KFY02711.1 - 0.11 12.1 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal region Translin PF01997.11 KFY02712.1 - 3.8e-55 186.6 0.0 4.4e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Translin family Lge1 PF11488.3 KFY02712.1 - 0.027 14.6 0.1 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Mannosyl_trans PF05007.8 KFY02713.1 - 1.7e-75 254.0 14.9 2.8e-75 253.3 10.3 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 KFY02713.1 - 1.3e-08 34.1 20.7 3.7e-08 32.6 14.4 1.7 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 KFY02713.1 - 9.8e-06 25.2 17.2 9.8e-06 25.2 11.9 2.7 1 1 2 3 3 3 1 Protein of unknown function (DUF2029) HPD PF05044.7 KFY02713.1 - 0.12 12.0 0.3 0.2 11.3 0.2 1.2 1 0 0 1 1 1 0 Homeo-prospero domain ABC_membrane PF00664.18 KFY02729.1 - 4.2e-95 318.2 40.1 8.2e-49 166.4 10.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFY02729.1 - 3.4e-66 221.6 0.3 1.9e-31 109.1 0.0 3.2 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.14 KFY02729.1 - 3e-12 46.2 0.0 0.00057 19.1 0.0 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFY02729.1 - 1.2e-09 38.6 0.4 0.15 11.9 0.0 4.3 2 2 0 3 3 3 3 AAA domain AAA_29 PF13555.1 KFY02729.1 - 3.2e-08 32.9 1.9 0.00058 19.3 0.1 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KFY02729.1 - 9.8e-08 32.1 0.7 0.0019 18.2 0.0 3.3 3 1 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 KFY02729.1 - 1e-06 29.5 0.0 0.13 13.0 0.0 3.1 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KFY02729.1 - 3.6e-06 25.8 1.9 0.03 12.9 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 KFY02729.1 - 5.3e-06 25.7 0.0 0.22 10.7 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 KFY02729.1 - 1e-05 25.0 0.4 0.26 10.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KFY02729.1 - 0.00025 21.1 0.7 2.9 8.0 0.0 4.3 4 1 0 4 4 4 1 AAA domain SbcCD_C PF13558.1 KFY02729.1 - 0.001 18.9 2.6 1.1 9.1 0.2 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KFY02729.1 - 0.0019 18.4 0.2 4.4 7.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.1 KFY02729.1 - 0.0027 17.6 0.4 0.62 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KFY02729.1 - 0.005 16.7 0.0 4.3 7.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 KFY02729.1 - 0.0054 16.5 1.4 1.6 8.4 0.0 2.7 3 0 0 3 3 2 1 Domain of unknown function DUF87 AAA_5 PF07728.9 KFY02729.1 - 0.0096 15.6 0.3 8.1 6.1 0.0 3.2 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KFY02729.1 - 0.03 14.2 0.0 7.4 6.4 0.0 3.3 4 0 0 4 4 3 0 AAA domain DUF815 PF05673.8 KFY02729.1 - 0.044 12.7 0.1 3.5 6.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF815) G-alpha PF00503.15 KFY02729.1 - 0.047 12.3 0.0 6.1 5.4 0.0 2.4 2 1 0 2 2 2 0 G-protein alpha subunit PRK PF00485.13 KFY02729.1 - 0.065 12.7 0.2 5.5 6.4 0.0 3.1 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family AAA_10 PF12846.2 KFY02729.1 - 0.12 11.7 4.5 19 4.5 0.0 3.9 4 0 0 4 4 4 0 AAA-like domain RNA_helicase PF00910.17 KFY02729.1 - 0.14 12.3 0.0 18 5.5 0.0 3.0 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.1 KFY02729.1 - 0.27 11.5 2.3 8.3 6.6 0.0 3.1 3 1 0 3 3 3 0 AAA domain Skp1 PF01466.14 KFY02730.1 - 4.7e-39 132.2 1.0 7.1e-39 131.6 0.7 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KFY02730.1 - 1.9e-20 72.7 0.1 4.1e-20 71.6 0.0 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 KFY02730.1 - 0.056 13.4 1.5 0.057 13.3 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Myb_DNA-binding PF00249.26 KFY02732.1 - 1.1e-12 47.7 1.5 4.4e-07 29.8 0.3 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFY02732.1 - 2.8e-11 43.3 1.5 2.7e-06 27.3 0.3 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain PAT1 PF09770.4 KFY02732.1 - 6.1 4.9 38.9 7.4 4.6 27.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glyco_hydro_16 PF00722.16 KFY02733.1 - 8e-43 145.8 4.0 1.2e-42 145.3 2.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 KFY02733.1 - 0.011 15.7 11.9 0.023 14.6 8.2 1.5 1 0 0 1 1 1 0 Chitin recognition protein WAP PF00095.16 KFY02733.1 - 0.021 14.7 4.0 0.042 13.8 2.8 1.4 1 0 0 1 1 1 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' WD40 PF00400.27 KFY02734.1 - 6.4e-54 178.0 16.8 1e-08 34.7 0.1 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 KFY02734.1 - 1.3e-10 40.8 0.1 3e-10 39.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFY02734.1 - 1.1e-08 34.4 0.1 3.9e-08 32.7 0.1 2.0 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KFY02734.1 - 7.6e-06 24.3 8.1 0.2 9.7 0.2 5.1 3 2 2 5 5 5 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 KFY02734.1 - 0.00071 19.3 0.1 2.1 8.1 0.0 4.5 4 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 KFY02734.1 - 0.0028 17.1 2.2 0.62 9.4 0.1 3.0 1 1 0 1 1 1 1 PQQ-like domain DUF1629 PF07791.6 KFY02734.1 - 0.19 11.6 0.0 0.41 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1629) Aha1_N PF09229.6 KFY02735.1 - 1.2e-36 125.6 0.1 1.4e-36 125.3 0.0 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal TRAP_alpha PF03896.11 KFY02736.1 - 1.5e-07 30.7 1.5 3e-07 29.7 0.1 1.9 2 0 0 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit Pkinase PF00069.20 KFY02737.1 - 1.7e-26 92.9 0.0 3e-26 92.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 KFY02737.1 - 2.3e-20 72.7 0.0 1e-07 32.1 0.0 5.1 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFY02737.1 - 7.9e-17 60.1 3.6 1.9e-08 33.6 0.0 7.4 8 0 0 8 8 8 3 Ankyrin repeat Pkinase_Tyr PF07714.12 KFY02737.1 - 1.3e-15 57.2 0.0 2.1e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.1 KFY02737.1 - 7.1e-06 26.3 0.3 0.046 14.2 0.0 5.8 5 1 1 6 6 6 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY02737.1 - 3.4e-05 23.6 0.3 0.11 12.7 0.0 6.0 7 0 0 7 7 7 1 Ankyrin repeat Ank_5 PF13857.1 KFY02737.1 - 0.014 15.6 0.5 13 6.1 0.0 4.4 3 2 1 4 4 4 0 Ankyrin repeats (many copies) HeLo PF14479.1 KFY02738.1 - 6.6e-12 45.6 0.1 1.1e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Prion-inhibition and propagation GHMP_kinases_N PF00288.21 KFY02739.1 - 1e-13 51.1 3.4 1.6e-13 50.5 1.6 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KFY02739.1 - 3.3e-05 24.0 0.4 6.6e-05 23.0 0.3 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Pantoate_ligase PF02569.10 KFY02740.1 - 1.4e-82 276.6 0.0 2.8e-82 275.6 0.0 1.5 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase DEAD PF00270.24 KFY02741.1 - 8.7e-40 135.9 0.2 6.6e-39 133.1 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFY02741.1 - 4.9e-21 74.3 0.0 1.3e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KFY02741.1 - 3.7e-16 58.3 0.0 7.5e-16 57.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KFY02741.1 - 0.0047 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1455 PF07306.6 KFY02741.1 - 0.051 13.6 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) WD40 PF00400.27 KFY02742.1 - 7.5e-13 47.8 6.1 0.067 13.0 0.0 6.5 6 1 0 6 6 6 4 WD domain, G-beta repeat Fungal_trans_2 PF11951.3 KFY02743.1 - 1.7e-10 40.0 1.2 2.4e-09 36.2 0.8 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF846 PF05832.7 KFY02745.1 - 1.3e-51 174.0 13.4 1.5e-51 173.8 9.3 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) bZIP_1 PF00170.16 KFY02746.1 - 1.4e-10 40.9 3.6 1.5e-09 37.6 1.7 2.7 2 0 0 2 2 2 1 bZIP transcription factor SAM_2 PF07647.12 KFY02746.1 - 5.3e-10 38.9 0.0 1.5e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFY02746.1 - 0.00028 21.0 0.0 0.00061 19.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) bZIP_2 PF07716.10 KFY02746.1 - 0.0022 17.8 7.8 0.0027 17.4 3.6 2.6 2 0 0 2 2 2 1 Basic region leucine zipper zf-C2H2_4 PF13894.1 KFY02746.1 - 1.5 9.3 13.5 5.8 7.4 1.3 4.0 3 0 0 3 3 3 0 C2H2-type zinc finger DUF2410 PF10307.4 KFY02747.1 - 0.0065 15.8 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) ATG22 PF11700.3 KFY02748.1 - 7.8e-192 637.9 17.4 9e-192 637.7 12.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KFY02748.1 - 0.0023 16.6 9.4 0.0023 16.6 6.5 3.3 3 1 1 4 4 4 3 Major Facilitator Superfamily Pex24p PF06398.6 KFY02748.1 - 0.22 10.2 7.8 0.77 8.4 3.6 2.5 1 1 0 2 2 2 0 Integral peroxisomal membrane peroxin Med14 PF08638.6 KFY02749.1 - 1.7e-67 226.4 0.0 2.8e-67 225.7 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 PfkB PF00294.19 KFY02751.1 - 1.9e-38 132.3 0.5 2.3e-38 132.0 0.3 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF498 PF04430.9 KFY02751.1 - 0.028 13.9 0.0 0.087 12.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) Zn_clus PF00172.13 KFY02752.1 - 9.1e-09 35.0 11.1 1.8e-08 34.1 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFY02752.1 - 5e-05 22.0 4.4 0.00021 20.0 0.0 2.5 3 0 0 3 3 3 2 Fungal specific transcription factor domain Sugar_tr PF00083.19 KFY02753.1 - 3.4e-106 355.5 32.9 6e-106 354.7 22.8 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY02753.1 - 4.9e-21 74.8 62.1 4e-13 48.8 18.4 3.6 2 1 2 4 4 4 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 KFY02753.1 - 1.3e-12 47.0 0.6 2.7e-12 46.0 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_2 PF13347.1 KFY02753.1 - 6.7e-05 21.4 8.3 6.7e-05 21.4 5.8 3.4 2 2 1 3 3 3 2 MFS/sugar transport protein Methyltransf_23 PF13489.1 KFY02754.1 - 1.3e-13 50.9 0.0 2.9e-13 49.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY02754.1 - 1.7e-13 50.4 0.0 2.6e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY02754.1 - 1.8e-13 50.7 0.0 3.4e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY02754.1 - 6.5e-13 49.2 0.0 1.4e-12 48.2 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY02754.1 - 5.8e-11 42.6 0.0 1.3e-10 41.4 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFY02754.1 - 1.6e-08 33.9 0.0 2.2e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KFY02754.1 - 2.3e-08 34.4 0.0 7.1e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFY02754.1 - 5.7e-06 26.3 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 KFY02754.1 - 0.00024 20.6 0.0 0.00074 19.0 0.0 1.7 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.1 KFY02754.1 - 0.00082 19.0 0.0 0.003 17.2 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.9 KFY02754.1 - 0.0037 16.6 0.0 0.0089 15.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 KFY02754.1 - 0.0053 15.8 0.0 0.0099 14.9 0.0 1.4 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase CMAS PF02353.15 KFY02754.1 - 0.0056 15.7 0.0 0.007 15.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Fig1 PF12351.3 KFY02755.1 - 1.6e-10 41.2 4.5 1.6e-10 41.2 3.1 1.6 1 1 1 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Claudin_2 PF13903.1 KFY02755.1 - 0.00043 20.0 2.2 0.00043 20.0 1.5 1.5 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction GMC_oxred_N PF00732.14 KFY02756.1 - 1.9e-45 155.3 0.5 2.8e-45 154.7 0.3 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFY02756.1 - 8.2e-24 84.5 1.7 1.6e-22 80.3 0.1 2.4 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 KFY02756.1 - 4.5e-08 32.3 1.0 0.0056 15.6 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFY02756.1 - 2.5e-07 29.9 0.2 6.7e-05 21.9 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.14 KFY02756.1 - 0.00019 20.6 0.1 0.00031 19.9 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KFY02756.1 - 0.00035 20.5 0.5 0.0015 18.5 0.4 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFY02756.1 - 0.001 18.9 0.4 0.0086 15.9 0.1 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFY02756.1 - 0.017 14.2 0.3 0.17 10.9 0.1 2.4 2 0 0 2 2 2 0 Thi4 family GDI PF00996.13 KFY02756.1 - 0.022 13.0 0.0 0.033 12.5 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Lycopene_cycl PF05834.7 KFY02756.1 - 0.062 12.2 0.1 0.17 10.7 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein PQ-loop PF04193.9 KFY02757.1 - 1.6e-21 75.6 8.1 2.3e-13 49.4 1.9 2.4 2 0 0 2 2 2 2 PQ loop repeat Med8 PF10232.4 KFY02758.1 - 1.2e-28 100.1 0.0 1.7e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 DUF937 PF06078.6 KFY02758.1 - 0.082 13.1 0.4 0.16 12.1 0.0 1.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF937) CFEM PF05730.6 KFY02761.1 - 0.00059 19.6 1.4 0.00059 19.6 0.9 2.2 2 0 0 2 2 2 1 CFEM domain PQ-loop PF04193.9 KFY02762.1 - 0.023 14.2 0.1 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 PQ loop repeat Sugar_tr PF00083.19 KFY02763.1 - 3.6e-75 253.2 23.2 4.4e-75 252.9 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY02763.1 - 4.5e-29 101.2 28.2 5.2e-20 71.4 11.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF749 PF05370.6 KFY02763.1 - 0.14 12.1 0.1 0.3 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF749) ADH_zinc_N_2 PF13602.1 KFY02764.1 - 9.2e-23 81.5 0.5 2.5e-22 80.1 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KFY02764.1 - 6e-15 54.9 0.0 1.3e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KFY02764.1 - 0.0048 16.9 0.1 0.008 16.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_8 PF13450.1 KFY02765.1 - 2.5e-14 53.0 0.0 6.4e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KFY02765.1 - 0.00012 21.2 0.0 0.0003 19.9 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KFY02765.1 - 0.00039 19.4 0.1 0.00086 18.3 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KFY02765.1 - 0.0005 19.8 0.2 0.029 14.1 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KFY02765.1 - 0.0039 17.1 0.0 0.017 14.9 0.0 2.0 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFY02765.1 - 0.006 15.4 0.1 0.014 14.2 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 KFY02765.1 - 0.0093 14.6 0.0 0.014 14.0 0.0 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.22 KFY02765.1 - 0.034 14.5 0.4 0.37 11.2 0.0 2.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFY02765.1 - 0.061 12.3 0.1 0.16 11.0 0.0 1.7 1 1 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KFY02765.1 - 0.081 11.3 0.0 0.3 9.4 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein K_oxygenase PF13434.1 KFY02765.1 - 0.16 10.8 1.5 0.39 9.5 0.1 2.1 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) DSBA PF01323.15 KFY02768.1 - 2.1e-16 60.0 0.0 2.4e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Lactococcin PF04369.8 KFY02768.1 - 0.051 13.4 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 Lactococcin-like family adh_short PF00106.20 KFY02769.1 - 1.2e-21 77.3 0.0 1.7e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFY02769.1 - 1.3e-11 44.7 0.0 1.6e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 KFY02769.1 - 0.0011 18.7 0.1 0.0017 18.0 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KFY02769.1 - 0.0011 19.0 0.0 0.0043 17.0 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KFY02769.1 - 0.0038 16.9 0.0 0.0056 16.3 0.0 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 KFY02769.1 - 0.067 13.6 0.1 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 KFY02769.1 - 0.2 10.4 0.8 0.22 10.4 0.0 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Glyco_hydro_2_N PF02837.13 KFY02770.1 - 1.1e-34 119.3 0.0 1.6e-33 115.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KFY02770.1 - 3.9e-30 104.7 0.0 1.3e-29 103.0 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 KFY02770.1 - 2.2e-16 60.2 0.3 4.7e-16 59.1 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 KFY02770.1 - 0.00013 22.2 0.1 0.0071 16.6 0.0 2.6 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain FAD_binding_4 PF01565.18 KFY02771.1 - 4.7e-20 71.4 0.4 1.1e-19 70.2 0.3 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFY02771.1 - 0.018 14.9 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like PTR2 PF00854.16 KFY02772.1 - 2.9e-40 138.2 11.7 7.1e-40 136.9 8.1 1.6 1 1 0 1 1 1 1 POT family CBM_1 PF00734.13 KFY02775.1 - 2.5e-15 55.8 7.7 5.4e-15 54.7 5.3 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL_2 PF13472.1 KFY02775.1 - 8.3e-14 52.1 2.8 1.6e-13 51.2 2.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFY02775.1 - 4.1e-08 33.3 0.5 6.6e-08 32.6 0.4 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 KFY02775.1 - 0.075 12.7 0.0 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family GspH PF12019.3 KFY02775.1 - 0.23 11.6 4.2 0.7 10.0 2.9 1.8 1 0 0 1 1 1 0 Type II transport protein GspH Sugar_tr PF00083.19 KFY02776.1 - 1.5e-92 310.5 27.9 1.9e-92 310.2 19.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY02776.1 - 8.7e-35 120.0 45.2 6e-31 107.4 14.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GST_N_3 PF13417.1 KFY02776.1 - 7.8e-07 29.2 0.1 1.7e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KFY02776.1 - 0.003 17.4 0.0 0.0091 15.8 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFY02776.1 - 0.0033 17.3 0.0 0.0088 16.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MFS_2 PF13347.1 KFY02776.1 - 0.0065 14.9 35.4 0.018 13.4 8.5 3.7 1 1 2 3 3 3 2 MFS/sugar transport protein GST_N_2 PF13409.1 KFY02776.1 - 0.016 15.1 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF3713 PF12506.3 KFY02776.1 - 0.086 12.9 5.0 5.3 7.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) OPT PF03169.10 KFY02777.1 - 1.8e-89 300.8 45.7 2.1e-89 300.6 31.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein YchF-GTPase_C PF06071.8 KFY02778.1 - 1.3e-36 124.1 0.2 3.5e-36 122.8 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KFY02778.1 - 2.3e-16 59.8 0.0 4.5e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFY02778.1 - 9e-07 28.2 0.0 1.7e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Mcp5_PH PF12814.2 KFY02779.1 - 1.8e-42 144.1 0.1 3.5e-42 143.1 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Zn_clus PF00172.13 KFY02783.1 - 1.5e-09 37.6 8.4 2.1e-09 37.1 5.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SnoaL_4 PF13577.1 KFY02784.1 - 5.1e-13 49.0 0.0 6.5e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 KFY02784.1 - 0.084 12.9 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain Ring_hydroxyl_B PF00866.13 KFY02784.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Ring hydroxylating beta subunit MFS_1 PF07690.11 KFY02785.1 - 9.1e-18 64.0 45.0 9.1e-18 64.0 31.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Amidase PF01425.16 KFY02786.1 - 1.4e-69 235.0 0.1 2e-69 234.5 0.1 1.1 1 0 0 1 1 1 1 Amidase ADH_zinc_N PF00107.21 KFY02787.1 - 0.0012 18.3 0.0 0.21 11.1 0.0 2.6 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Peptidase_S28 PF05577.7 KFY02788.1 - 8.9e-53 179.4 1.1 1.1e-38 132.9 0.1 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 adh_short PF00106.20 KFY02789.1 - 5.2e-16 59.0 0.3 7.8e-15 55.1 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFY02789.1 - 2.2e-07 30.8 0.0 4.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFY02789.1 - 2.8e-05 23.8 0.0 6.2e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KFY02789.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFY02789.1 - 0.13 12.2 0.0 0.53 10.2 0.0 2.0 2 1 0 2 2 2 0 NADH(P)-binding Aldo_ket_red PF00248.16 KFY02790.1 - 1.9e-62 210.6 0.0 2.3e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3584 PF12128.3 KFY02793.1 - 7 3.8 25.8 0.25 8.6 5.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Cyclin_N PF00134.18 KFY02801.1 - 3.6e-13 49.1 0.0 7.8e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KFY02801.1 - 1.1e-10 42.0 0.2 1.3e-09 38.6 0.1 2.4 1 1 0 1 1 1 1 Cyclin Nuc_sug_transp PF04142.10 KFY02802.1 - 1.4e-79 266.6 10.3 1.4e-79 266.6 7.1 1.6 2 0 0 2 2 2 1 Nucleotide-sugar transporter UAA PF08449.6 KFY02802.1 - 2.5e-09 36.4 14.0 3.8e-08 32.5 9.8 2.1 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 KFY02802.1 - 1.1e-07 31.6 21.9 0.00034 20.2 0.6 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 KFY02802.1 - 1.6e-07 31.4 0.9 1.6e-07 31.4 0.6 2.4 2 0 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 KFY02802.1 - 6.4e-05 22.9 24.3 9.9e-05 22.3 2.3 2.8 2 1 0 2 2 2 2 EamA-like transporter family DUF454 PF04304.8 KFY02802.1 - 0.31 11.1 8.5 1.1 9.3 2.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF454) FUSC_2 PF13515.1 KFY02802.1 - 1.1 9.2 10.7 0.13 12.1 3.5 2.3 2 0 0 2 2 2 0 Fusaric acid resistance protein-like Sec63 PF02889.11 KFY02803.1 - 7.4e-46 156.8 0.0 1.1e-45 156.2 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 KFY02803.1 - 1.4e-24 86.4 0.0 3e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFY02803.1 - 1.2e-07 31.4 0.0 3.2e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFY02803.1 - 3.9e-07 30.0 0.0 1.1e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Cdd1 PF11731.3 KFY02803.1 - 0.0072 16.2 0.0 0.024 14.5 0.0 1.9 1 0 0 1 1 1 1 Pathogenicity locus UvrD-helicase PF00580.16 KFY02803.1 - 0.032 13.5 1.7 0.06 12.6 0.0 2.3 4 0 0 4 4 4 0 UvrD/REP helicase N-terminal domain AAA_30 PF13604.1 KFY02803.1 - 0.032 13.7 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KFY02803.1 - 0.037 14.1 0.0 0.094 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain HHH_5 PF14520.1 KFY02803.1 - 0.083 13.0 0.0 0.27 11.4 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain PDR_CDR PF06422.7 KFY02805.1 - 0.00046 19.8 0.0 0.00055 19.5 0.0 1.2 1 0 0 1 1 1 1 CDR ABC transporter DUF4562 PF15123.1 KFY02805.1 - 0.0026 17.6 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4562) VirB8 PF04335.8 KFY02805.1 - 0.014 14.9 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 VirB8 protein Ferric_reduct PF01794.14 KFY02806.1 - 6.5e-17 61.7 6.1 6.5e-17 61.7 4.2 2.5 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 KFY02806.1 - 7.8e-16 58.3 0.0 6e-10 39.2 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KFY02806.1 - 2.9e-13 49.5 0.0 5.7e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 KFY02806.1 - 0.0013 19.2 0.0 1.3 9.6 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain DUF4405 PF14358.1 KFY02806.1 - 0.64 10.1 8.6 0.46 10.6 1.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) GDI PF00996.13 KFY02807.1 - 4.8e-38 130.6 0.0 7.3e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor Ldh_2 PF02615.9 KFY02808.1 - 6.5e-94 314.3 0.0 8.1e-94 314.0 0.0 1.1 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase ING PF12998.2 KFY02811.1 - 0.0011 19.2 0.6 0.0048 17.1 0.4 2.1 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding DUF1117 PF06547.7 KFY02811.1 - 0.031 14.3 0.1 0.067 13.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) DTHCT PF08070.6 KFY02811.1 - 0.33 11.6 11.4 1.9 9.2 3.5 2.9 2 0 0 2 2 2 0 DTHCT (NUC029) region DUF4404 PF14357.1 KFY02811.1 - 0.54 10.7 0.0 0.54 10.7 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4404) DUF3294 PF07957.6 KFY02812.1 - 0.011 15.3 1.2 0.011 15.3 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3294) PCP_red PF08369.5 KFY02812.1 - 0.023 14.5 0.1 0.023 14.5 0.0 2.0 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Cu-oxidase_2 PF07731.9 KFY02819.1 - 7.8e-42 142.0 7.5 3.4e-39 133.4 1.0 3.3 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KFY02819.1 - 5.7e-40 135.7 2.6 5.6e-37 126.0 0.2 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KFY02819.1 - 2.2e-37 128.4 1.6 5.4e-35 120.6 0.1 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 KFY02819.1 - 0.003 17.4 0.0 12 5.8 0.0 3.9 3 2 0 3 3 3 2 Cupredoxin-like domain FA_hydroxylase PF04116.8 KFY02824.1 - 3.7e-12 46.6 2.4 3.7e-12 46.6 1.6 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Stn1 PF10451.4 KFY02824.1 - 0.037 12.8 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Telomere regulation protein Stn1 FAD_binding_3 PF01494.14 KFY02826.1 - 7.1e-29 100.9 0.0 1.5e-28 99.9 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 KFY02826.1 - 7.8e-05 21.6 0.0 0.024 13.4 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase DAO PF01266.19 KFY02826.1 - 0.00018 20.5 0.1 0.23 10.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFY02826.1 - 0.00054 20.3 0.1 0.73 10.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFY02826.1 - 0.00068 18.6 0.0 1.2 7.9 0.0 3.7 3 1 1 4 4 4 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KFY02826.1 - 0.0035 17.3 0.1 0.011 15.7 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFY02826.1 - 0.068 12.0 0.0 0.46 9.2 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 KFY02826.1 - 0.12 11.4 0.1 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Myosin_N PF02736.14 KFY02826.1 - 0.16 11.6 0.5 19 5.0 0.0 2.4 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain NAD_binding_10 PF13460.1 KFY02827.1 - 2.6e-27 96.0 0.1 3e-27 95.8 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFY02827.1 - 8.6e-08 31.9 0.0 1.6e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KFY02827.1 - 3.6e-06 26.4 0.1 4.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 KFY02827.1 - 0.011 15.6 0.0 0.032 14.2 0.0 1.9 1 1 1 2 2 2 0 TrkA-N domain RmlD_sub_bind PF04321.12 KFY02827.1 - 0.035 12.9 0.0 0.062 12.1 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DapB_N PF01113.15 KFY02827.1 - 0.13 12.1 0.0 0.37 10.7 0.0 1.8 1 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus FTR1 PF03239.9 KFY02828.1 - 9.6e-82 274.3 6.9 1.5e-81 273.7 4.8 1.2 1 0 0 1 1 1 1 Iron permease FTR1 family Fungal_trans PF04082.13 KFY02828.1 - 5.8e-14 51.5 0.1 1e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cytochrom_B_N PF00033.14 KFY02828.1 - 0.0033 16.8 0.4 0.0033 16.8 0.3 2.1 2 1 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB DUF3169 PF11368.3 KFY02828.1 - 0.05 12.7 1.0 0.12 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) RPW8 PF05659.6 KFY02830.1 - 0.00029 20.3 1.2 0.7 9.4 0.1 2.5 2 0 0 2 2 2 2 Arabidopsis broad-spectrum mildew resistance protein RPW8 Occludin_ELL PF07303.8 KFY02830.1 - 0.0023 18.6 3.5 0.027 15.1 0.0 3.1 3 0 0 3 3 3 1 Occludin homology domain BLOC1_2 PF10046.4 KFY02830.1 - 0.012 15.7 5.4 0.27 11.3 0.5 3.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.6 KFY02830.1 - 0.1 12.4 7.0 7.7 6.4 0.2 3.7 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1451 PF07295.6 KFY02830.1 - 0.13 12.0 2.6 0.87 9.3 0.1 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF1451) Reo_sigmaC PF04582.7 KFY02830.1 - 0.15 11.2 8.4 0.056 12.6 0.2 2.9 1 1 1 3 3 3 0 Reovirus sigma C capsid protein GED PF02212.13 KFY02830.1 - 0.18 11.7 2.8 0.21 11.5 0.3 2.4 2 0 0 2 2 2 0 Dynamin GTPase effector domain Syntaxin-6_N PF09177.6 KFY02830.1 - 0.48 10.8 8.1 7.4 7.0 0.1 4.1 2 1 2 4 4 4 0 Syntaxin 6, N-terminal Abhydrolase_6 PF12697.2 KFY02831.1 - 1.5e-18 67.5 0.2 5.9e-18 65.5 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFY02831.1 - 1.3e-07 31.4 0.0 0.0054 16.4 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY02831.1 - 7.8e-07 28.8 0.0 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DDE_3 PF13358.1 KFY02832.1 - 2.3e-15 56.5 0.0 4e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 KFY02832.1 - 2.5e-07 30.6 0.9 6.9e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 Transposase HTH_IclR PF09339.5 KFY02832.1 - 0.00033 20.1 0.1 0.00067 19.1 0.1 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_24 PF13412.1 KFY02832.1 - 0.0025 17.1 0.0 0.26 10.6 0.0 2.5 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_23 PF13384.1 KFY02832.1 - 0.0037 16.8 0.7 0.075 12.7 0.0 2.7 2 0 0 2 2 2 1 Homeodomain-like domain HTH_20 PF12840.2 KFY02832.1 - 0.0089 15.8 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 KFY02832.1 - 0.01 15.3 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_29 PF13551.1 KFY02832.1 - 0.025 14.7 1.8 3 8.0 0.1 2.9 3 0 0 3 3 3 0 Winged helix-turn helix HTH_5 PF01022.15 KFY02832.1 - 0.029 14.0 0.1 0.049 13.2 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family DRIM PF07539.7 KFY02832.1 - 0.029 13.7 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Down-regulated in metastasis HTH_40 PF14493.1 KFY02832.1 - 0.11 12.7 0.2 0.31 11.2 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_10 PF04967.7 KFY02832.1 - 0.12 11.9 0.5 0.38 10.3 0.0 2.0 3 0 0 3 3 3 0 HTH DNA binding domain HTH_9 PF08221.6 KFY02832.1 - 0.17 11.8 0.0 0.39 10.6 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain TetR_N PF00440.18 KFY02832.1 - 0.21 11.2 0.3 0.69 9.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, tetR family Zn_clus PF00172.13 KFY02833.1 - 3.2e-07 30.1 6.5 5.4e-07 29.4 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3716 PF12511.3 KFY02833.1 - 0.064 12.8 4.6 0.14 11.7 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) HJURP_C PF12347.3 KFY02833.1 - 0.073 12.6 0.0 6.4 6.4 0.0 3.4 3 0 0 3 3 3 0 Holliday junction regulator protein family C-terminal repeat CFEM PF05730.6 KFY02834.1 - 3.8e-09 36.2 10.5 7e-09 35.3 7.3 1.5 1 0 0 1 1 1 1 CFEM domain Invas_SpaK PF03519.9 KFY02834.1 - 0.15 11.9 0.4 19 5.1 0.0 2.4 2 0 0 2 2 2 0 Invasion protein B family Amidohydro_4 PF13147.1 KFY02839.1 - 5.1e-24 85.7 0.2 1.7e-12 47.9 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase Exo_endo_phos PF03372.18 KFY02839.1 - 2.5e-19 70.1 0.0 4.3e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Amidohydro_1 PF01979.15 KFY02839.1 - 1.7e-17 64.0 0.0 6.3e-11 42.5 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 KFY02839.1 - 6.9e-10 38.7 0.1 4.4e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KFY02839.1 - 4e-08 32.9 1.0 1.1e-07 31.5 0.7 1.7 1 0 0 1 1 1 1 Amidohydrolase adh_short PF00106.20 KFY02840.1 - 4.3e-23 82.0 2.1 6.5e-23 81.4 1.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFY02840.1 - 7.4e-14 52.0 0.2 9.9e-14 51.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFY02840.1 - 3.8e-06 26.6 0.7 6.3e-06 25.9 0.5 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFY02840.1 - 5e-06 26.6 0.5 9e-06 25.8 0.3 1.6 1 1 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 KFY02840.1 - 0.0037 16.8 0.3 0.0083 15.6 0.2 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.16 KFY02840.1 - 0.0048 16.3 0.5 0.014 14.8 0.4 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family SRR1 PF07985.7 KFY02841.1 - 9e-09 35.1 0.0 1.5e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 SRR1 RRP7 PF12923.2 KFY02841.1 - 0.098 12.6 3.2 0.21 11.6 2.2 1.6 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) DDOST_48kD PF03345.9 KFY02843.1 - 8e-163 541.8 0.0 9e-163 541.7 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Pet191_N PF10203.4 KFY02844.1 - 2e-16 59.7 0.2 2.6e-16 59.3 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Ank_2 PF12796.2 KFY02845.1 - 6.7e-157 510.3 37.8 6.9e-22 77.5 0.3 11.5 3 3 6 11 11 11 11 Ankyrin repeats (3 copies) Ank PF00023.25 KFY02845.1 - 2.7e-142 456.0 63.5 4.6e-08 32.4 0.2 24.4 23 1 1 24 24 24 23 Ankyrin repeat Ank_3 PF13606.1 KFY02845.1 - 6.8e-99 313.7 39.2 0.0001 22.1 0.0 23.6 23 1 1 24 24 24 21 Ankyrin repeat Ank_4 PF13637.1 KFY02845.1 - 4.5e-97 316.8 29.4 8.4e-10 38.9 0.0 17.0 8 5 12 20 20 20 18 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY02845.1 - 3.8e-95 309.7 39.5 2.4e-08 33.9 0.2 19.7 5 3 17 22 22 22 20 Ankyrin repeats (many copies) PGAP1 PF07819.8 KFY02845.1 - 0.0043 16.6 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein RVP PF00077.15 KFY02845.1 - 0.11 12.4 0.1 12 5.9 0.0 3.7 3 0 0 3 3 3 0 Retroviral aspartyl protease SchA_CurD PF04486.7 KFY02845.1 - 0.17 11.7 0.5 2.8 7.7 0.0 3.0 3 0 0 3 3 3 0 SchA/CurD like domain Hep_59 PF07052.6 KFY02846.1 - 7.6e-11 42.3 0.1 1.3e-10 41.5 0.1 1.5 1 0 0 1 1 1 1 Hepatocellular carcinoma-associated antigen 59 Acylphosphatase PF00708.13 KFY02847.1 - 7.8e-22 77.1 1.4 8.7e-22 77.0 1.0 1.0 1 0 0 1 1 1 1 Acylphosphatase Ank_2 PF12796.2 KFY02848.1 - 4.8e-28 97.3 0.1 1.8e-15 57.0 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFY02848.1 - 1.8e-24 84.2 0.0 8.5e-06 25.3 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KFY02848.1 - 5.2e-20 71.4 0.3 5.1e-06 26.8 0.0 4.2 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY02848.1 - 3.6e-16 58.8 0.5 2.8e-07 30.5 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY02848.1 - 1.1e-14 52.9 0.0 0.01 16.0 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Glyco_hydro_12 PF01670.11 KFY02849.1 - 1.6e-37 128.7 1.5 1.6e-37 128.7 1.1 1.9 1 1 1 2 2 2 1 Glycosyl hydrolase family 12 Phage_holin_5 PF06946.6 KFY02849.1 - 2.3 8.4 5.9 0.41 10.8 0.9 2.2 2 1 0 2 2 2 0 Phage holin FAA_hydrolase PF01557.13 KFY02850.1 - 1.5e-52 178.2 0.0 1.7e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Pol_alpha_B_N PF08418.5 KFY02851.1 - 7 6.1 6.5 9.1 5.7 4.5 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal NUDIX PF00293.23 KFY02853.1 - 6.4e-12 45.2 0.0 1.3e-11 44.2 0.0 1.5 1 1 0 1 1 1 1 NUDIX domain HTH_13 PF11972.3 KFY02853.1 - 0.095 12.5 0.1 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 HTH DNA binding domain PWI PF01480.12 KFY02854.1 - 5.1e-29 100.1 0.0 8.1e-29 99.5 0.0 1.3 1 0 0 1 1 1 1 PWI domain DEAD PF00270.24 KFY02856.1 - 1.1e-20 73.8 0.1 3.3e-20 72.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFY02856.1 - 3.2e-17 62.1 0.0 2.5e-16 59.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.5 KFY02856.1 - 3.9e-15 55.4 1.4 7.1e-15 54.6 0.4 2.0 2 0 0 2 2 2 1 RQC domain HRDC PF00570.18 KFY02856.1 - 0.0036 16.9 0.0 0.012 15.3 0.0 1.9 1 0 0 1 1 1 1 HRDC domain IF3_C PF00707.17 KFY02856.1 - 0.069 12.8 0.1 22 4.8 0.0 2.7 2 0 0 2 2 2 0 Translation initiation factor IF-3, C-terminal domain Abhydrolase_6 PF12697.2 KFY02858.1 - 2.2e-13 50.6 0.0 3.1e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFY02858.1 - 8.8e-07 28.7 0.0 1.5e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY02858.1 - 0.0048 16.4 0.0 0.006 16.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Glyco_tranf_2_3 PF13641.1 KFY02860.1 - 7.1e-16 58.7 0.0 1e-15 58.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KFY02860.1 - 1e-06 28.1 0.0 2.2e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KFY02860.1 - 1.8e-05 24.4 0.0 2.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Abhydrolase_6 PF12697.2 KFY02861.1 - 1.7e-26 93.4 2.1 2e-26 93.2 1.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY02861.1 - 4.4e-16 59.1 0.0 6.3e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFY02861.1 - 2.8e-09 36.8 0.0 5.1e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KFY02861.1 - 0.00039 19.7 0.1 0.049 12.8 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Esterase PF00756.15 KFY02861.1 - 0.0048 16.3 0.0 0.0079 15.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 KFY02861.1 - 0.012 15.0 0.0 0.04 13.3 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PhoPQ_related PF10142.4 KFY02861.1 - 0.038 12.4 0.0 0.062 11.7 0.0 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein FSH1 PF03959.8 KFY02861.1 - 0.14 11.5 0.0 0.65 9.4 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.5 KFY02861.1 - 0.15 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein PGAP1 PF07819.8 KFY02861.1 - 0.15 11.5 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Fungal_trans_2 PF11951.3 KFY02862.1 - 2.4e-17 62.6 0.4 3.1e-17 62.2 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Drf_FH1 PF06346.7 KFY02862.1 - 0.076 12.5 4.4 0.13 11.8 3.1 1.2 1 0 0 1 1 1 0 Formin Homology Region 1 Sugar_tr PF00083.19 KFY02863.1 - 2.2e-79 267.1 9.5 3.1e-78 263.3 6.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY02863.1 - 1.3e-13 50.4 29.0 6.7e-13 48.0 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFY02863.1 - 0.0054 15.1 1.6 0.0054 15.1 1.1 3.7 3 1 0 3 3 3 1 MFS/sugar transport protein Ank_2 PF12796.2 KFY02864.1 - 3.3e-28 97.8 9.2 9.3e-17 61.1 1.0 3.3 2 1 2 4 4 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFY02864.1 - 3.4e-26 89.6 12.8 3.8e-07 29.5 0.0 6.1 5 1 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 KFY02864.1 - 4.5e-22 77.5 11.4 1.2e-07 31.7 0.8 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY02864.1 - 7.6e-21 72.1 6.3 5.5e-05 23.0 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KFY02864.1 - 1e-17 64.0 13.7 1.4e-08 35.0 0.2 6.6 3 1 4 8 8 8 6 Ankyrin repeats (many copies) TPR_12 PF13424.1 KFY02864.1 - 3.5e-06 26.8 3.7 2.6e-05 24.0 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFY02864.1 - 0.0021 17.7 0.9 0.083 12.7 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KFY02864.1 - 0.018 14.9 0.1 0.17 11.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFY02864.1 - 0.023 15.0 4.9 0.24 11.7 0.6 3.0 1 1 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFY02864.1 - 0.063 13.0 4.2 0.31 10.9 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 KFY02864.1 - 0.25 11.0 3.3 0.57 9.8 1.3 2.3 1 1 1 2 2 2 0 TPR repeat TPR_2 PF07719.12 KFY02864.1 - 1.3 9.1 4.2 0.98 9.5 0.6 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.11 KFY02865.1 - 2.9e-42 144.6 74.1 6.2e-39 133.7 40.7 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2052 PF09747.4 KFY02881.1 - 0.082 12.8 0.0 0.082 12.8 0.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) GMC_oxred_N PF00732.14 KFY02882.1 - 5e-47 160.4 0.0 6.9e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFY02882.1 - 3e-33 115.1 0.1 5.4e-33 114.3 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KFY02882.1 - 3.2e-06 26.2 0.0 0.031 13.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KFY02882.1 - 7.7e-05 21.7 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KFY02882.1 - 0.00044 19.2 0.0 0.062 12.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KFY02882.1 - 0.00054 19.9 0.0 0.0038 17.2 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KFY02882.1 - 0.0014 17.5 0.0 0.13 11.0 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KFY02882.1 - 0.024 14.5 0.0 0.06 13.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CBM_11 PF03425.8 KFY02882.1 - 0.082 12.5 0.2 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 Carbohydrate binding domain (family 11) HI0933_like PF03486.9 KFY02882.1 - 0.098 11.1 0.0 1.4 7.2 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein EHN PF06441.7 KFY02882.1 - 0.11 12.4 0.0 0.33 10.8 0.0 1.8 1 0 0 1 1 1 0 Epoxide hydrolase N terminus NAD_binding_9 PF13454.1 KFY02882.1 - 0.13 11.9 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KFY02882.1 - 0.2 10.6 0.0 0.32 9.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Fungal_trans PF04082.13 KFY02883.1 - 1.4e-07 30.6 0.3 3.5e-07 29.3 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY02883.1 - 3e-07 30.2 13.4 9.4e-07 28.6 9.3 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N PF02798.15 KFY02884.1 - 2.4e-06 27.5 0.0 5.3e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KFY02884.1 - 7.6e-06 26.3 0.0 1.1e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFY02884.1 - 0.0011 18.7 0.0 0.0034 17.2 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KFY02884.1 - 0.0022 17.9 0.0 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFY02884.1 - 0.008 16.3 0.0 0.024 14.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KFY02885.1 - 2.5e-06 27.6 0.0 2.3e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain NAD_binding_1 PF00175.16 KFY02885.1 - 5.5e-06 26.9 0.0 1.2e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KFY02885.1 - 1.4e-05 25.1 0.0 0.0039 17.2 0.0 2.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KFY02885.1 - 4.4e-05 23.4 0.0 0.0002 21.2 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain GST_N_2 PF13409.1 KFY02885.1 - 0.00047 20.0 0.0 0.0015 18.4 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFY02885.1 - 0.0026 17.6 0.0 0.0053 16.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pyridox_oxidase PF01243.15 KFY02885.1 - 0.003 17.5 0.0 2.7 8.0 0.0 2.9 2 1 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Gag_p10 PF02337.12 KFY02885.1 - 0.13 12.0 0.0 0.99 9.1 0.0 2.3 2 0 0 2 2 2 0 Retroviral GAG p10 protein Glyco_hydro_43 PF04616.9 KFY02886.1 - 1.2e-14 54.0 0.3 3.2e-14 52.7 0.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Zn_clus PF00172.13 KFY02886.1 - 6.5e-10 38.7 10.6 1.3e-09 37.8 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFY02886.1 - 0.00015 20.5 0.0 0.0016 17.1 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Bac_luciferase PF00296.15 KFY02887.1 - 1.1e-60 205.3 0.4 1.4e-60 205.0 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase SSF PF00474.12 KFY02888.1 - 6.2e-22 77.7 30.0 1.1e-21 76.9 20.8 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family DUF997 PF06196.7 KFY02888.1 - 0.32 10.5 11.4 0.51 9.8 0.5 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF997) ADH_zinc_N PF00107.21 KFY02889.1 - 2.6e-06 26.9 0.2 2.6e-06 26.9 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFY02889.1 - 4.9e-06 26.2 0.0 1.3e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Dicty_REP PF05086.7 KFY02889.1 - 0.082 10.6 0.3 0.098 10.3 0.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 KFY02889.1 - 0.77 9.5 5.0 6.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein CAP59_mtransfer PF11735.3 KFY02891.1 - 1.6e-65 220.7 0.0 2.2e-65 220.2 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF1517 PF07466.6 KFY02892.1 - 0.0056 15.7 0.4 0.01 14.8 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) Plasmodium_Vir PF05795.6 KFY02892.1 - 0.13 11.4 1.6 0.21 10.7 1.1 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CCDC50_N PF15295.1 KFY02892.1 - 0.15 11.9 2.3 0.76 9.7 0.1 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus Ribosomal_L14 PF00238.14 KFY02894.1 - 3.7e-45 152.6 0.8 4.2e-45 152.4 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SET PF00856.23 KFY02895.1 - 2e-09 37.9 0.4 4e-08 33.7 0.1 2.9 2 1 0 2 2 2 1 SET domain BTB PF00651.26 KFY02896.1 - 0.00027 20.9 0.0 0.0011 18.8 0.0 2.0 2 1 0 2 2 2 1 BTB/POZ domain Anillin PF08174.6 KFY02897.1 - 5.7e-32 110.6 0.5 1.8e-31 109.0 0.3 1.9 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 KFY02897.1 - 3.4e-09 36.8 0.0 1.3e-08 35.0 0.0 2.0 1 0 0 1 1 1 1 PH domain RNase_P_pop3 PF08228.6 KFY02898.1 - 1.1e-06 28.5 0.0 2.2e-06 27.6 0.0 1.5 2 0 0 2 2 2 1 RNase P subunit Pop3 GATase PF00117.23 KFY02899.1 - 2.5e-38 131.4 0.0 6.9e-38 130.0 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 KFY02899.1 - 1.1e-34 118.0 0.0 1.9e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 KFY02899.1 - 3.6e-12 45.7 0.0 2.5e-07 29.8 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 KFY02899.1 - 1.3e-07 31.3 0.0 3.3e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 ThiI PF02568.9 KFY02899.1 - 0.0016 17.9 0.1 0.0041 16.6 0.0 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 KFY02899.1 - 0.0063 15.1 0.1 0.017 13.6 0.1 1.6 2 0 0 2 2 2 1 tRNA methyl transferase Asn_synthase PF00733.16 KFY02899.1 - 0.0076 15.7 0.2 0.017 14.6 0.0 1.6 2 0 0 2 2 2 1 Asparagine synthase QueC PF06508.8 KFY02899.1 - 0.022 14.0 0.0 0.36 10.0 0.0 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.14 KFY02899.1 - 0.079 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.15 KFY02899.1 - 0.14 11.6 0.1 0.21 11.0 0.0 1.5 1 1 0 1 1 1 0 PP-loop family UCH PF00443.24 KFY02900.1 - 1.3e-43 149.0 0.7 2.7e-43 148.0 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.3 KFY02900.1 - 6.9e-43 146.4 0.0 1.1e-42 145.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH_1 PF13423.1 KFY02900.1 - 3.5e-15 56.2 0.4 8.6e-15 54.9 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Clathrin PF00637.15 KFY02901.1 - 0.066 12.8 0.1 0.28 10.7 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS PPR_3 PF13812.1 KFY02901.1 - 0.14 12.4 0.4 12 6.4 0.0 3.7 3 1 0 3 3 3 0 Pentatricopeptide repeat domain UPF0220 PF05255.6 KFY02902.1 - 0.073 12.3 0.0 0.075 12.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) COX7a PF02238.10 KFY02902.1 - 0.19 11.4 2.2 0.41 10.4 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIa Clathrin_lg_ch PF01086.12 KFY02903.1 - 2.9e-68 230.1 8.2 3.4e-68 229.9 5.7 1.0 1 0 0 1 1 1 1 Clathrin light chain CTD_bind PF04818.8 KFY02904.1 - 1.1e-20 73.5 0.2 2.2e-20 72.6 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. DUF3277 PF11681.3 KFY02904.1 - 0.0012 18.3 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3277) CTK3 PF12243.3 KFY02904.1 - 0.013 15.1 0.3 0.026 14.1 0.2 1.5 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 LepA_C PF06421.7 KFY02904.1 - 0.032 14.1 0.4 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 GTP-binding protein LepA C-terminus CDC37_N PF03234.9 KFY02905.1 - 7.4e-55 185.9 7.0 7.4e-55 185.9 4.8 2.7 2 1 1 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 KFY02905.1 - 9.1e-44 148.9 0.3 2.6e-43 147.5 0.0 1.9 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 KFY02905.1 - 2.2e-25 88.3 1.7 2.2e-25 88.3 1.2 2.6 2 1 1 3 3 3 1 Cdc37 C terminal domain HTH_22 PF13309.1 KFY02905.1 - 0.12 12.1 0.5 3.2 7.5 0.0 3.2 3 1 0 3 3 3 0 HTH domain Seryl_tRNA_N PF02403.17 KFY02905.1 - 1.8 8.6 9.4 0.26 11.3 0.5 3.5 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF1227 PF06777.6 KFY02911.1 - 8.4e-63 210.4 0.5 2.7e-62 208.7 0.3 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 KFY02911.1 - 1.3e-52 177.7 0.4 2.8e-52 176.6 0.3 1.6 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 KFY02911.1 - 1.9e-43 148.3 0.0 5.6e-43 146.7 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.10 KFY02911.1 - 0.00025 20.9 0.7 0.033 14.0 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KFY02911.1 - 0.00059 19.3 0.0 0.1 12.0 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 KFY02911.1 - 0.0015 17.3 0.0 0.016 14.0 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 KFY02911.1 - 0.022 14.8 0.5 2.9 8.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.1 KFY02911.1 - 0.028 13.9 0.1 0.099 12.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 KFY02911.1 - 0.052 12.7 0.1 3.2 6.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein PRP3 PF08572.5 KFY02912.1 - 1e-69 234.3 5.5 1.4e-69 233.8 3.8 1.2 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 KFY02912.1 - 3.1e-39 133.5 0.9 3.1e-39 133.5 0.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) RNA_pol_Rpb1_5 PF04998.12 KFY02913.1 - 3.7e-89 298.6 0.1 8.1e-89 297.5 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KFY02913.1 - 1.1e-64 217.4 0.1 2.4e-64 216.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KFY02913.1 - 2.3e-35 121.6 0.0 7e-35 120.0 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 KFY02913.1 - 1.9e-33 116.1 0.0 2.7e-23 82.7 0.0 2.7 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 KFY02913.1 - 8.4e-18 64.0 0.4 3.4e-17 62.1 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 EPSP_synthase PF00275.15 KFY02914.1 - 1.9e-128 428.4 0.0 2.8e-128 427.9 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 KFY02914.1 - 3.7e-100 334.1 0.0 7.7e-100 333.1 0.0 1.6 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 KFY02914.1 - 1.2e-62 211.4 0.0 4.8e-62 209.5 0.0 1.9 2 0 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.17 KFY02914.1 - 1.7e-37 128.7 0.0 1.3e-35 122.6 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 KFY02914.1 - 1.9e-23 82.2 0.0 5e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KFY02914.1 - 5.7e-11 42.6 0.0 1.4e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 KFY02914.1 - 1.4e-09 37.6 0.0 3.4e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 KFY02914.1 - 7.9e-05 23.4 0.0 0.00027 21.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain Pyr_redox_3 PF13738.1 KFY02914.1 - 0.077 13.0 0.1 0.24 11.4 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CBM_X PF06204.6 KFY02914.1 - 0.08 12.4 0.0 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 Putative carbohydrate binding domain AAA_18 PF13238.1 KFY02914.1 - 0.089 13.1 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KFY02914.1 - 0.12 11.4 0.0 1 8.4 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin zf-C2H2 PF00096.21 KFY02915.1 - 3.3e-09 36.5 12.7 0.003 17.8 1.3 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFY02915.1 - 5.9e-07 29.3 14.5 0.0023 18.1 1.0 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.7 KFY02915.1 - 1.2 9.2 5.9 3.5 7.8 1.0 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-CCHC PF00098.18 KFY02919.1 - 3.1e-53 175.3 98.8 1.7e-06 27.6 2.1 11.4 11 0 0 11 11 11 11 Zinc knuckle zf-CCHC_4 PF14392.1 KFY02919.1 - 9.3e-08 31.6 79.4 0.029 14.0 0.4 11.4 11 0 0 11 11 11 10 Zinc knuckle zf-CCHC_3 PF13917.1 KFY02919.1 - 0.0007 19.2 74.2 0.24 11.1 0.1 10.3 2 2 8 10 10 10 7 Zinc knuckle zf-CCHC_2 PF13696.1 KFY02919.1 - 0.00083 18.7 58.2 0.018 14.5 0.1 10.9 8 3 4 12 12 12 6 Zinc knuckle zf-C2H2_4 PF13894.1 KFY02920.1 - 1.2e-07 31.5 12.9 0.083 13.2 0.2 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFY02920.1 - 0.0022 18.2 2.3 1.2 9.5 0.3 3.2 2 0 0 2 2 2 2 Zinc-finger double domain zf-TRAF PF02176.13 KFY02920.1 - 0.016 15.6 0.6 0.068 13.5 0.4 2.1 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2 PF00096.21 KFY02920.1 - 0.018 15.3 20.9 0.2 12.0 0.6 4.7 4 1 0 4 4 4 0 Zinc finger, C2H2 type NmrA PF05368.8 KFY02921.1 - 2.1e-30 105.6 0.0 4.6e-30 104.6 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFY02921.1 - 1.8e-05 24.8 0.0 2.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 KFY02921.1 - 0.0025 17.7 0.0 0.0053 16.7 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.12 KFY02921.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Methyltransf_23 PF13489.1 KFY02922.1 - 1.9e-18 66.7 0.0 3.4e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY02922.1 - 1.9e-07 31.6 0.0 3.8e-06 27.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY02922.1 - 1.4e-06 28.0 0.0 3.2e-05 23.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY02922.1 - 0.0002 21.8 0.0 0.00063 20.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY02922.1 - 0.00062 20.2 0.0 0.0013 19.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY02922.1 - 0.00095 19.4 0.0 0.0032 17.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KFY02922.1 - 0.011 14.8 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 KFY02922.1 - 0.022 14.7 0.0 0.058 13.3 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 KFY02922.1 - 0.073 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 KFY02922.1 - 0.096 12.7 0.0 0.25 11.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain HET PF06985.6 KFY02923.1 - 2.9e-34 118.2 0.1 1.2e-33 116.2 0.1 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.8 KFY02923.1 - 0.014 14.3 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Phg_2220_C PF09524.5 KFY02923.1 - 0.17 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) DUF4231 PF14015.1 KFY02924.1 - 0.034 14.1 2.7 0.22 11.5 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Seryl_tRNA_N PF02403.17 KFY02924.1 - 1.3 9.1 24.6 0.31 11.0 0.1 5.6 5 1 0 5 5 5 0 Seryl-tRNA synthetase N-terminal domain MFS_1 PF07690.11 KFY02928.1 - 3.6e-30 104.8 24.5 3.6e-30 104.8 17.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily ALMT PF11744.3 KFY02928.1 - 0.8 8.2 2.9 1.5 7.3 2.0 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter DNA_methylase PF00145.12 KFY02929.1 - 1.1e-30 106.8 0.0 2.6e-30 105.7 0.0 1.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase WD40 PF00400.27 KFY02933.1 - 4.2e-45 150.0 2.3 9.9e-14 50.6 0.1 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat APS_kinase PF01583.15 KFY02933.1 - 8.6e-08 31.9 0.2 0.015 14.9 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase PQQ_3 PF13570.1 KFY02933.1 - 2.1e-06 27.8 2.5 0.57 10.5 0.1 3.4 3 0 0 3 3 3 2 PQQ-like domain PQQ_2 PF13360.1 KFY02933.1 - 1e-05 25.1 3.0 2.1e-05 24.1 2.1 1.4 1 0 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 KFY02933.1 - 1.6e-05 23.2 0.1 0.2 9.7 0.0 3.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 AAA_16 PF13191.1 KFY02933.1 - 6.5e-05 22.9 0.4 0.2 11.6 0.1 2.7 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KFY02933.1 - 0.00014 21.9 0.3 0.75 9.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 KFY02933.1 - 0.00018 20.4 0.0 0.49 9.1 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain AAA_17 PF13207.1 KFY02933.1 - 0.00022 22.0 0.1 1.6 9.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain Proteasome_A_N PF10584.4 KFY02933.1 - 0.00028 20.1 0.1 3.9 6.8 0.0 3.6 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature AAA_30 PF13604.1 KFY02933.1 - 0.00039 20.0 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KFY02933.1 - 0.00071 19.4 0.1 1.8 8.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KFY02933.1 - 0.00094 19.3 0.1 1.1 9.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Cytochrom_D1 PF02239.11 KFY02933.1 - 0.003 15.9 0.0 0.0059 14.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain NACHT PF05729.7 KFY02933.1 - 0.0037 16.9 0.3 1.4 8.5 0.0 2.8 2 1 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 KFY02933.1 - 0.0048 16.6 0.0 5.8 6.7 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 KFY02933.1 - 0.0079 16.4 0.2 7.2 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 KFY02933.1 - 0.0085 15.3 0.0 4.1 6.5 0.0 2.2 2 0 0 2 2 2 2 PhoH-like protein PD40 PF07676.7 KFY02933.1 - 0.017 14.7 0.1 42 3.9 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat RNA_helicase PF00910.17 KFY02933.1 - 0.019 15.1 0.5 9.6 6.4 0.1 2.6 2 1 0 2 2 2 0 RNA helicase Thymidylate_kin PF02223.12 KFY02933.1 - 0.02 14.2 0.1 5.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase AAA_29 PF13555.1 KFY02933.1 - 0.026 14.0 0.3 12 5.4 0.0 3.0 3 0 0 3 3 3 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KFY02933.1 - 0.13 12.5 0.0 29 4.9 0.0 2.5 2 0 0 2 2 2 0 ABC transporter PIF1 PF05970.9 KFY02933.1 - 0.25 10.2 0.0 15 4.4 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase HeLo PF14479.1 KFY02934.1 - 4.8e-43 147.3 1.2 5.6e-43 147.1 0.9 1.0 1 0 0 1 1 1 1 Prion-inhibition and propagation HET-s_218-289 PF11558.3 KFY02934.1 - 1.8e-09 37.3 2.6 3.8e-09 36.3 1.8 1.5 1 0 0 1 1 1 1 Het-s 218-289 DUF2090 PF09863.4 KFY02934.1 - 0.0071 15.2 0.1 0.0094 14.8 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2090) DUF1192 PF06698.6 KFY02934.1 - 0.015 15.1 0.5 4.8 7.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Fucose_iso_N2 PF07882.7 KFY02934.1 - 0.12 12.0 0.3 0.24 11.0 0.0 1.6 2 0 0 2 2 2 0 L-fucose isomerase, second N-terminal domain Trypan_PARP PF05887.6 KFY02936.1 - 1.6 8.5 9.3 2.8 7.7 6.5 1.4 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Vps8 PF12816.2 KFY02939.1 - 1.6e-68 229.8 0.0 3.9e-68 228.5 0.0 1.7 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 KFY02939.1 - 1.7e-06 27.6 0.5 0.052 13.1 0.0 3.7 3 0 0 3 3 3 2 Region in Clathrin and VPS BRO1 PF03097.13 KFY02940.1 - 0.21 10.3 0.6 0.4 9.3 0.0 1.6 2 0 0 2 2 2 0 BRO1-like domain eIF-3c_N PF05470.7 KFY02942.1 - 5.9 4.8 7.4 0.63 8.0 0.1 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus COG6 PF06419.6 KFY02943.1 - 3.3e-231 768.7 13.1 3.8e-231 768.5 9.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.6 KFY02943.1 - 0.00051 19.9 0.4 0.0044 16.8 0.1 2.7 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Reprolysin_4 PF13583.1 KFY02943.1 - 0.09 12.2 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Abi_C PF14355.1 KFY02943.1 - 0.11 12.4 0.1 0.63 10.0 0.0 2.4 2 0 0 2 2 2 0 Abortive infection C-terminus Sec23_trunk PF04811.10 KFY02944.1 - 3.8e-70 236.0 0.0 5.4e-70 235.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KFY02944.1 - 1.1e-23 82.5 0.1 1.6e-22 78.8 0.0 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KFY02944.1 - 3.9e-18 65.7 0.0 7.9e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KFY02944.1 - 8.3e-18 63.6 5.1 1.4e-17 62.8 3.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KFY02944.1 - 6.3e-08 32.2 0.0 1.3e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Sporozoite_P67 PF05642.6 KFY02944.1 - 1.8 6.3 6.7 3.1 5.5 4.6 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TMEMspv1-c74-12 PF11044.3 KFY02945.1 - 0.0074 15.8 0.5 0.012 15.1 0.1 1.6 1 1 0 1 1 1 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein Fungal_trans_2 PF11951.3 KFY02946.1 - 5.8e-14 51.4 0.1 1.9e-13 49.7 0.0 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY02946.1 - 1.3e-05 24.9 9.7 2.2e-05 24.2 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 KFY02947.1 - 7.2e-11 41.5 5.6 0.0081 16.0 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat LCAT PF02450.10 KFY02948.1 - 4.7e-95 318.8 0.0 1.3e-94 317.4 0.0 1.7 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase DUF1917 PF08939.5 KFY02948.1 - 2.3e-61 207.6 0.0 3.4e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Abhydrolase_5 PF12695.2 KFY02948.1 - 0.01 15.5 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_2 PF01674.13 KFY02948.1 - 0.014 14.7 0.0 0.041 13.1 0.0 1.7 1 0 0 1 1 1 0 Lipase (class 2) Imm2 PF14426.1 KFY02948.1 - 0.13 12.3 0.1 0.67 9.9 0.0 2.1 2 0 0 2 2 2 0 Immunity protein Imm2 Sld5 PF05916.6 KFY02949.1 - 2.3e-10 40.7 0.0 3.9e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein PHD PF00628.24 KFY02949.1 - 3.4e-08 33.0 8.1 5.7e-08 32.3 5.6 1.4 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.1 KFY02949.1 - 0.0023 17.2 2.8 0.0046 16.2 2.0 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 KFY02949.1 - 0.45 9.8 10.8 0.049 12.9 3.8 2.2 2 1 0 2 2 2 0 PHD-finger C1_1 PF00130.17 KFY02949.1 - 1.8 8.3 7.4 0.22 11.2 2.0 1.8 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Sod_Fe_C PF02777.13 KFY02950.1 - 5.5e-38 129.0 0.7 5.5e-38 129.0 0.5 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KFY02950.1 - 4e-29 100.7 2.3 6.5e-29 100.0 1.6 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Imm15 PF15590.1 KFY02950.1 - 0.077 12.0 1.3 2.3 7.3 0.0 3.3 3 1 1 4 4 4 0 Immunity protein 15 RabGAP-TBC PF00566.13 KFY02951.1 - 4.5e-37 127.6 0.0 8.9e-36 123.3 0.0 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Ribonuclease_3 PF00636.21 KFY02952.1 - 2.2e-11 44.1 0.0 5e-11 43.0 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KFY02952.1 - 3.5e-11 43.1 0.0 4.3e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Beta-lactamase PF00144.19 KFY02953.1 - 8.7e-40 136.7 0.0 1.2e-33 116.5 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase DUF3471 PF11954.3 KFY02953.1 - 1.5e-09 37.5 0.0 2.8e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) PAF-AH_p_II PF03403.8 KFY02954.1 - 1.8e-15 56.1 0.0 5e-07 28.3 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 KFY02954.1 - 2.4e-14 53.2 0.1 3.9e-14 52.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFY02954.1 - 4e-08 33.4 0.1 6.1e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KFY02954.1 - 4.6e-07 28.9 0.0 9.6e-07 27.9 0.0 1.5 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KFY02954.1 - 0.0087 14.8 1.7 0.068 11.9 0.3 2.3 2 1 0 2 2 2 1 Chlorophyllase Abhydrolase_1 PF00561.15 KFY02954.1 - 0.018 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 KFY02954.1 - 0.04 13.5 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Fungal_trans_2 PF11951.3 KFY02955.1 - 9.2e-19 67.2 0.0 2e-18 66.1 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY02955.1 - 2.6e-05 24.0 11.0 4.3e-05 23.3 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SIMPL PF04402.9 KFY02956.1 - 8.7e-29 100.8 4.6 1.1e-28 100.5 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DUF4424 PF14415.1 KFY02956.1 - 0.048 13.1 0.1 0.076 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4424) adh_short PF00106.20 KFY02958.1 - 5.5e-12 45.9 0.0 8.6e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFY02958.1 - 1e-06 28.5 0.0 6.1e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KFY02958.1 - 0.0012 18.6 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFY02958.1 - 0.0047 16.3 0.0 0.021 14.2 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 KFY02958.1 - 0.057 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain O-FucT PF10250.4 KFY02958.1 - 0.12 11.4 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase Glyco_hydro_16 PF00722.16 KFY02959.1 - 2.1e-20 72.8 0.2 3.8e-20 71.9 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 bZIP_2 PF07716.10 KFY02960.1 - 1.3 8.8 7.7 6.4 6.6 1.7 3.4 2 1 0 2 2 2 0 Basic region leucine zipper Pectate_lyase PF03211.8 KFY02963.1 - 1.9e-61 207.2 6.2 2.2e-61 206.9 4.3 1.0 1 0 0 1 1 1 1 Pectate lyase OPT PF03169.10 KFY02964.1 - 6.3e-123 411.4 46.1 8.3e-123 411.0 31.9 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2207 PF09972.4 KFY02964.1 - 0.01 14.4 0.9 0.03 12.8 0.6 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4181 PF13789.1 KFY02964.1 - 0.041 13.8 5.3 3.1 7.7 0.6 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) DUF3093 PF11292.3 KFY02964.1 - 0.16 11.7 5.6 1.1 9.1 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) Ribonuc_P_40 PF08584.6 KFY02964.1 - 0.17 10.8 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit DUF3237 PF11578.3 KFY02965.1 - 2.9e-06 26.6 0.1 4e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) FAD_binding_4 PF01565.18 KFY02966.1 - 2.1e-17 62.8 2.7 4.9e-17 61.7 1.9 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFY02966.1 - 8.9e-07 28.7 0.0 1.8e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like HATPase_c PF02518.21 KFY02968.1 - 1.3e-18 66.6 0.1 2.7e-18 65.6 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KFY02968.1 - 1.7e-16 60.2 0.0 5.4e-12 45.7 0.0 3.6 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.20 KFY02968.1 - 1.3e-13 50.7 0.0 3.6e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 KFY02968.1 - 7.4e-06 26.0 0.3 0.0014 18.7 0.1 3.4 3 1 1 4 4 4 1 GAF domain GAF_2 PF13185.1 KFY02968.1 - 0.0092 16.4 0.1 0.028 14.8 0.0 1.9 2 0 0 2 2 2 1 GAF domain HATPase_c_2 PF13581.1 KFY02968.1 - 0.095 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain DUF2823 PF11034.3 KFY02969.1 - 1e-33 115.2 11.9 1.2e-33 115.0 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) CSF-1 PF05337.6 KFY02969.1 - 0.061 12.6 0.9 0.062 12.6 0.6 1.1 1 0 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) MFS_1 PF07690.11 KFY02970.1 - 1.1e-26 93.4 19.2 7.2e-26 90.7 11.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF423 PF04241.10 KFY02970.1 - 4.5 7.2 6.6 28 4.7 1.3 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF423) Glyco_hydro_88 PF07470.8 KFY02971.1 - 1.5e-13 50.4 0.0 2.1e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Fungal_trans PF04082.13 KFY02972.1 - 3e-17 62.3 0.2 5.5e-17 61.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY02972.1 - 8e-07 28.8 10.4 1.7e-06 27.8 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.12 KFY02972.1 - 0.36 9.5 3.4 0.8 8.4 2.4 1.5 1 0 0 1 1 1 0 Clusterin DUF2264 PF10022.4 KFY02973.1 - 5e-122 407.0 0.0 6.5e-122 406.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Beta-lactamase PF00144.19 KFY02975.1 - 2.4e-24 85.9 0.2 3.5e-24 85.4 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase Glyco_hydro_1 PF00232.13 KFY02976.1 - 3.8e-78 262.7 0.5 2.7e-76 256.6 0.4 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Fungal_trans_2 PF11951.3 KFY02976.1 - 1.1e-34 119.7 0.2 3e-34 118.2 0.1 1.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY02976.1 - 4.1e-09 36.2 5.1 4.1e-09 36.2 3.5 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ERG4_ERG24 PF01222.12 KFY02977.1 - 9.1e-147 489.0 20.2 1e-146 488.8 14.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family 2-Hacid_dh_C PF02826.14 KFY02981.1 - 1.2e-35 122.2 0.0 5e-23 81.1 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 KFY02981.1 - 0.018 14.4 0.0 0.03 13.6 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 KFY02981.1 - 0.07 13.1 0.0 0.15 12.0 0.0 1.6 1 1 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.12 KFY02981.1 - 0.071 13.5 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Gp_dh_N PF00044.19 KFY02981.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Lipase_GDSL_2 PF13472.1 KFY02982.1 - 1.2e-26 93.9 0.0 1.3e-26 93.7 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 KFY02982.1 - 7.4e-08 32.3 0.0 2.3e-06 27.4 0.0 2.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFY02982.1 - 8.1e-06 25.8 0.0 3.6e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Pribosyltran PF00156.22 KFY02983.1 - 5.6e-09 35.7 0.2 5.6e-08 32.5 0.1 2.1 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UQ_con PF00179.21 KFY02985.1 - 9.3e-26 89.9 0.2 1.3e-25 89.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KFY02985.1 - 0.14 12.0 0.1 0.22 11.3 0.1 1.3 1 0 0 1 1 1 0 RWD domain Bac_surface_Ag PF01103.18 KFY02986.1 - 9.2e-43 146.9 1.0 1.2e-42 146.5 0.7 1.1 1 0 0 1 1 1 1 Surface antigen EBP PF05241.7 KFY02987.1 - 2e-65 219.4 8.6 2.4e-65 219.1 5.9 1.0 1 0 0 1 1 1 1 Emopamil binding protein TRIC PF05197.8 KFY02987.1 - 0.27 10.6 4.5 2.1 7.6 0.7 2.3 2 0 0 2 2 2 0 TRIC channel IKI3 PF04762.7 KFY02988.1 - 6e-07 27.7 0.0 5.1e-06 24.6 0.0 1.8 1 1 0 2 2 2 1 IKI3 family eIF2A PF08662.6 KFY02988.1 - 0.00086 19.0 0.2 7.5 6.2 0.0 4.1 4 1 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 KFY02988.1 - 0.0024 17.6 10.2 3.7 7.5 0.3 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat PD40 PF07676.7 KFY02988.1 - 0.25 11.0 2.2 0.52 10.0 0.0 2.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat MoaC PF01967.16 KFY02989.1 - 7.9e-50 168.0 0.2 1.4e-49 167.2 0.1 1.5 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 KFY02989.1 - 2.9e-34 117.4 0.0 6.3e-34 116.4 0.0 1.6 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 KFY02989.1 - 3.5e-21 76.0 0.0 7.4e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 KFY02989.1 - 0.0012 19.0 0.0 0.0032 17.5 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KFY02989.1 - 0.0034 17.3 0.0 0.008 16.2 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain EHN PF06441.7 KFY02991.1 - 6.2e-37 125.9 1.8 2.1e-36 124.2 0.1 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KFY02991.1 - 8.6e-14 51.9 0.3 1.7e-13 51.0 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY02991.1 - 1.6e-09 37.6 0.0 5.8e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold BatD PF13584.1 KFY02992.1 - 0.031 12.8 0.0 0.049 12.2 0.0 1.2 1 0 0 1 1 1 0 Oxygen tolerance Methyltransf_28 PF02636.12 KFY02993.1 - 3.6e-80 269.0 0.0 4.3e-80 268.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.20 KFY02994.1 - 4.2e-62 209.6 0.0 6.7e-62 208.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY02994.1 - 6.8e-28 97.4 0.0 9.8e-28 96.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFY02994.1 - 0.00014 20.9 0.0 0.00029 19.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like DUF3621 PF12285.3 KFY02994.1 - 0.1 12.7 0.3 0.1 12.7 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3621) APH PF01636.18 KFY02994.1 - 0.18 11.5 4.6 0.21 11.2 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family eIF3_subunit PF08597.5 KFY02994.1 - 2.3 7.7 15.7 3.4 7.1 10.9 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Rtf2 PF04641.7 KFY02994.1 - 7.3 5.7 10.8 13 4.9 7.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Pex14_N PF04695.8 KFY02995.1 - 3.7 7.5 7.5 7.1 6.6 5.2 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DAHP_synth_1 PF00793.15 KFY02997.1 - 5e-97 323.8 0.1 5.8e-97 323.6 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Myb_DNA-bind_6 PF13921.1 KFY03012.1 - 0.001 19.1 0.9 0.0021 18.1 0.6 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Fungal_trans_2 PF11951.3 KFY03013.1 - 2.7e-19 69.0 3.6 4.6e-19 68.2 2.5 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Abhydro_lipase PF04083.11 KFY03013.1 - 0.032 13.5 0.0 0.091 12.1 0.0 1.8 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Nol1_Nop2_Fmu PF01189.12 KFY03014.1 - 3.5e-100 335.0 0.0 1.4e-99 333.0 0.0 1.9 2 0 0 2 2 2 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 KFY03014.1 - 0.0039 16.7 2.0 0.0058 16.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 KFY03014.1 - 0.0045 16.9 0.0 0.0098 15.8 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Blt1 PF12754.2 KFY03015.1 - 1.1e-27 97.5 0.4 2.8e-21 76.4 0.1 2.4 1 1 1 2 2 2 2 Cell-cycle control medial ring component ubiquitin PF00240.18 KFY03015.1 - 0.064 12.6 0.1 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin family Cpn60_TCP1 PF00118.19 KFY03016.1 - 1.8e-115 386.3 9.2 2.2e-115 386.0 6.4 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cofilin_ADF PF00241.15 KFY03016.1 - 2.4e-32 111.4 0.3 4.9e-32 110.4 0.2 1.6 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein NOPS PF08075.6 KFY03016.1 - 0.18 12.2 0.0 0.4 11.1 0.0 1.6 1 0 0 1 1 1 0 NOPS (NUC059) domain Cmyb_C PF09316.5 KFY03017.1 - 0.22 11.1 5.7 0.27 10.8 1.6 2.4 2 0 0 2 2 2 0 C-myb, C-terminal Med3 PF11593.3 KFY03020.1 - 0.15 11.2 2.4 0.15 11.2 1.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Nop25 PF09805.4 KFY03020.1 - 0.5 10.4 6.5 0.72 9.9 4.5 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF605 PF04652.11 KFY03021.1 - 1.2 8.4 18.4 1.5 8.1 12.8 1.1 1 0 0 1 1 1 0 Vta1 like Lipase_GDSL PF00657.17 KFY03046.1 - 1.3e-14 54.5 0.2 2.2e-14 53.8 0.1 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.11 KFY03048.1 - 2.6e-33 115.2 33.2 2.6e-33 115.2 23.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Septin PF00735.13 KFY03049.1 - 7.2e-122 405.8 0.0 7.2e-122 405.8 0.0 1.9 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KFY03049.1 - 7.4e-07 29.1 0.0 1.6e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 KFY03049.1 - 5.8e-05 23.4 1.0 0.023 14.9 0.0 2.5 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 KFY03049.1 - 0.0001 21.5 0.7 0.0011 18.2 0.5 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KFY03049.1 - 0.00015 21.2 0.4 0.0068 15.8 0.0 3.1 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 KFY03049.1 - 0.00098 18.6 2.2 0.0025 17.3 1.4 2.0 1 1 0 1 1 1 1 AAA-like domain AIG1 PF04548.11 KFY03049.1 - 0.0015 17.6 1.3 0.0048 16.0 0.0 2.3 2 0 0 2 2 2 1 AIG1 family FtsK_SpoIIIE PF01580.13 KFY03049.1 - 0.0015 18.0 0.1 0.022 14.2 0.0 2.7 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_16 PF13191.1 KFY03049.1 - 0.0017 18.4 0.0 0.012 15.6 0.0 2.3 3 0 0 3 3 2 1 AAA ATPase domain Miro PF08477.8 KFY03049.1 - 0.0023 18.4 0.0 0.0087 16.5 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 KFY03049.1 - 0.006 16.7 0.3 0.03 14.4 0.0 2.4 2 2 1 3 3 3 1 AAA domain Ras PF00071.17 KFY03049.1 - 0.0071 15.7 1.2 0.03 13.6 0.0 2.5 3 1 0 3 3 3 1 Ras family AAA_29 PF13555.1 KFY03049.1 - 0.0089 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 KFY03049.1 - 0.02 14.4 0.1 4.3 6.8 0.0 3.0 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 KFY03049.1 - 0.032 14.0 6.9 0.46 10.2 0.0 3.4 3 1 0 3 3 2 0 Dynamin family MobB PF03205.9 KFY03049.1 - 0.054 13.2 0.2 0.21 11.2 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KFY03049.1 - 0.061 13.4 0.4 0.65 10.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 KFY03049.1 - 0.08 12.5 0.5 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain YlqD PF11068.3 KFY03049.1 - 0.14 12.2 10.6 0.26 11.3 7.3 1.4 1 0 0 1 1 1 0 YlqD protein Strep_SA_rep PF06696.6 KFY03049.1 - 0.25 11.1 3.3 0.34 10.7 1.1 2.0 1 1 1 2 2 2 0 Streptococcal surface antigen repeat Exonuc_VII_L PF02601.10 KFY03049.1 - 0.26 10.4 8.1 0.47 9.6 5.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit IncA PF04156.9 KFY03049.1 - 0.8 9.2 9.9 1.3 8.6 6.8 1.3 1 0 0 1 1 1 0 IncA protein Phage_GPO PF05929.6 KFY03049.1 - 1.2 8.3 6.5 1.8 7.7 4.5 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF87 PF01935.12 KFY03049.1 - 2.3 7.9 7.4 2.9 7.6 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF87 V_ATPase_I PF01496.14 KFY03049.1 - 7.1 4.3 10.4 12 3.6 7.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Clat_adaptor_s PF01217.15 KFY03050.1 - 1.5e-54 183.5 1.2 3.5e-54 182.3 0.9 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PDZ_1 PF12812.2 KFY03050.1 - 1.1e-53 179.0 0.0 2.1e-34 117.2 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.1 KFY03050.1 - 5.5e-14 52.1 0.1 2e-12 47.1 0.0 2.7 2 1 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 KFY03050.1 - 6.3e-13 48.4 0.1 0.00013 21.7 0.0 4.3 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.19 KFY03050.1 - 3.7e-10 39.8 0.0 0.0004 20.5 0.0 3.7 3 0 0 3 3 3 3 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 KFY03050.1 - 1.4e-05 24.7 0.0 3.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.1 KFY03050.1 - 0.011 15.5 0.6 1.2 8.9 0.1 3.1 3 0 0 3 3 3 0 Tricorn protease PDZ domain Peptidase_S7 PF00949.16 KFY03050.1 - 0.22 10.9 0.0 0.47 9.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.11 KFY03050.1 - 0.32 10.2 0.2 0.52 9.5 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) DUF2422 PF10337.4 KFY03051.1 - 2.6e-31 108.9 0.7 5.9e-19 68.1 0.0 4.5 3 2 2 5 5 5 2 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 KFY03051.1 - 4.4e-10 39.5 19.2 4.4e-10 39.5 13.3 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 KFY03051.1 - 6.6e-07 28.3 7.4 6.6e-07 28.3 5.1 3.0 3 0 0 3 3 3 2 Aluminium activated malate transporter FUSC PF04632.7 KFY03051.1 - 4.4e-06 25.4 9.5 4.4e-06 25.4 6.6 3.1 3 1 0 3 3 3 1 Fusaric acid resistance protein family DUF2421 PF10334.4 KFY03051.1 - 0.0004 20.0 0.0 0.0008 19.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) Ist1 PF03398.9 KFY03052.1 - 8.5e-63 210.6 2.5 1.1e-62 210.2 1.7 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway GATA PF00320.22 KFY03053.1 - 0.0025 17.0 3.8 0.0025 17.0 2.6 3.2 2 0 0 2 2 2 1 GATA zinc finger DNA_topoisoIV PF00521.15 KFY03054.1 - 1.2e-121 406.5 0.1 5.6e-121 404.3 0.0 1.9 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KFY03054.1 - 2.9e-33 114.5 4.3 7e-33 113.2 3.0 1.6 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 KFY03054.1 - 4.3e-12 45.8 0.0 1.5e-11 44.0 0.0 2.0 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 KFY03054.1 - 1.2e-09 37.8 0.0 4.5e-09 35.9 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Dynamin_N PF00350.18 KFY03056.1 - 3.2e-06 27.0 0.9 1.3e-05 25.0 0.0 2.4 2 1 0 2 2 2 1 Dynamin family ABC_tran PF00005.22 KFY03056.1 - 0.00088 19.5 0.0 0.0049 17.1 0.0 2.3 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 KFY03056.1 - 0.0009 18.4 0.0 0.0026 16.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KFY03056.1 - 0.0023 17.8 0.0 0.0085 16.0 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.8 KFY03056.1 - 0.0038 16.0 0.0 0.012 14.4 0.0 1.8 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.1 KFY03056.1 - 0.0052 16.7 0.0 0.019 14.9 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.22 KFY03056.1 - 0.062 12.7 0.0 0.35 10.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 KFY03056.1 - 0.067 13.6 0.0 0.22 12.0 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 KFY03056.1 - 0.1 12.1 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 KFY03056.1 - 0.11 11.6 0.0 0.26 10.4 0.0 1.6 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain TPR_11 PF13414.1 KFY03057.1 - 6.5e-10 38.5 2.3 2.4e-05 23.8 0.4 3.2 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 KFY03057.1 - 4.5e-08 32.3 0.5 0.22 11.1 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFY03057.1 - 4.2e-07 29.3 0.2 0.3 11.1 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFY03057.1 - 0.036 14.7 0.1 0.036 14.7 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat Nuc-transf PF10127.4 KFY03057.1 - 0.056 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotidyltransferase TPR_17 PF13431.1 KFY03057.1 - 0.088 13.0 0.0 0.74 10.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR_3 PF13812.1 KFY03058.1 - 1.1e-21 75.2 7.8 0.014 15.5 0.0 9.1 8 0 0 8 8 8 6 Pentatricopeptide repeat domain PPR_2 PF13041.1 KFY03058.1 - 1.1e-18 66.8 0.5 0.095 12.6 0.0 8.4 6 2 2 8 8 8 5 PPR repeat family PPR PF01535.15 KFY03058.1 - 4.7e-08 32.5 14.4 3.4 7.8 0.0 7.3 8 0 0 8 8 8 4 PPR repeat TPR_12 PF13424.1 KFY03058.1 - 0.04 13.8 1.4 2.5 8.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFY03058.1 - 0.072 12.9 0.1 0.83 9.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat LSM PF01423.17 KFY03059.1 - 2.1e-15 56.0 0.0 2.8e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KFY03059.1 - 0.015 15.1 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain P12 PF12669.2 KFY03060.1 - 0.02 15.0 3.5 0.02 15.0 2.4 2.5 2 1 0 2 2 2 0 Virus attachment protein p12 family Collagen PF01391.13 KFY03060.1 - 0.099 12.1 0.5 0.26 10.8 0.4 1.6 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Zip PF02535.17 KFY03060.1 - 1.2 8.0 8.2 1.9 7.3 5.7 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Glyco_hydro_7 PF00840.15 KFY03061.1 - 3.9e-195 648.2 18.0 4.6e-195 648.0 12.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Ammonium_transp PF00909.16 KFY03074.1 - 9e-81 271.3 21.2 1e-80 271.1 14.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family CRT10 PF08728.5 KFY03076.1 - 2.7e-18 65.3 0.0 7.4e-10 37.4 0.0 2.3 2 0 0 2 2 2 2 CRT10 Cellulase PF00150.13 KFY03078.1 - 4.8e-12 45.6 0.0 6.5e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Git3 PF11710.3 KFY03082.1 - 1.3e-05 24.8 0.9 1.4e-05 24.7 0.6 1.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 DUF4117 PF13491.1 KFY03082.1 - 0.079 12.3 1.1 0.092 12.1 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4117) WD40 PF00400.27 KFY03084.1 - 0 1320.8 135.9 5e-14 51.5 0.2 32.7 32 0 0 32 32 32 32 WD domain, G-beta repeat Nup160 PF11715.3 KFY03084.1 - 3.8e-42 144.1 118.8 0.046 11.8 0.1 28.7 2 2 25 27 27 27 21 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KFY03084.1 - 3e-20 71.8 40.9 0.00042 18.7 0.0 11.7 3 3 8 13 13 13 9 Cytochrome D1 heme domain NACHT PF05729.7 KFY03084.1 - 1.7e-18 66.8 0.1 1.1e-08 34.9 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 KFY03084.1 - 3.2e-10 40.2 1.5 2.8e-05 24.1 0.0 3.7 2 1 0 2 2 2 2 AAA ATPase domain DUF3312 PF11768.3 KFY03084.1 - 1.3e-09 36.8 16.6 0.4 8.8 0.0 11.5 5 3 10 16 16 16 4 Protein of unknown function (DUF3312) DUF1258 PF06869.7 KFY03084.1 - 2.9e-07 29.8 18.5 14 4.6 0.0 15.1 3 3 15 23 23 23 0 Protein of unknown function (DUF1258) Nbas_N PF15492.1 KFY03084.1 - 3e-07 29.8 49.6 7.6 5.5 0.2 17.0 2 1 13 17 17 17 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 KFY03084.1 - 6.6e-07 28.8 9.4 52 3.6 0.0 12.0 12 0 0 12 12 12 0 WD40-like Beta Propeller Repeat APS_kinase PF01583.15 KFY03084.1 - 9.8e-06 25.3 0.2 0.063 12.9 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase Proteasome_A_N PF10584.4 KFY03084.1 - 1.7e-05 24.0 8.4 57 3.1 0.0 9.0 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature AAA_22 PF13401.1 KFY03084.1 - 4e-05 23.7 0.0 0.32 11.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain WXG100 PF06013.7 KFY03084.1 - 4.6e-05 23.3 24.6 54 3.8 0.0 14.4 16 1 0 16 16 16 0 Proteins of 100 residues with WXG AAA_17 PF13207.1 KFY03084.1 - 0.0011 19.8 0.0 4.6 8.0 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA PF00004.24 KFY03084.1 - 0.0054 16.9 0.1 8.1 6.6 0.0 3.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KFY03084.1 - 0.0087 16.3 0.0 2.7 8.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KFY03084.1 - 0.009 15.8 0.2 7.5 6.4 0.0 3.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KFY03084.1 - 0.014 15.5 0.3 3 8.0 0.0 2.9 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 KFY03084.1 - 0.051 13.2 0.0 0.14 11.8 0.0 1.7 2 0 0 2 2 1 0 Archaeal ATPase Med16 PF11635.3 KFY03084.1 - 0.059 11.3 32.5 0.25 9.2 0.3 6.0 1 1 3 5 5 5 0 Mediator complex subunit 16 PhoH PF02562.11 KFY03084.1 - 0.069 12.3 0.0 11 5.1 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein Thymidylate_kin PF02223.12 KFY03084.1 - 0.11 11.8 0.5 12 5.1 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase CbiA PF01656.18 KFY03084.1 - 0.22 10.8 1.2 3 7.2 0.1 2.9 4 0 0 4 4 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain FlxA PF14282.1 KFY03084.1 - 0.23 11.3 0.2 0.74 9.7 0.1 1.9 1 0 0 1 1 1 0 FlxA-like protein Filament PF00038.16 KFY03084.1 - 0.24 10.8 1.2 0.48 9.8 0.8 1.4 1 0 0 1 1 1 0 Intermediate filament protein TPR_MLP1_2 PF07926.7 KFY03084.1 - 0.33 10.7 1.1 0.86 9.3 0.7 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein HOOK PF05622.7 KFY03084.1 - 0.34 8.6 1.1 0.54 7.9 0.8 1.2 1 0 0 1 1 1 0 HOOK protein MAD PF05557.8 KFY03084.1 - 0.53 8.3 1.3 0.95 7.4 0.9 1.3 1 0 0 1 1 1 0 Mitotic checkpoint protein PQQ_3 PF13570.1 KFY03084.1 - 2.1 8.7 38.8 1.2 9.4 0.1 12.7 14 2 2 16 16 12 0 PQQ-like domain AAA_13 PF13166.1 KFY03084.1 - 5.8 5.2 5.7 9.9 4.4 0.3 2.9 3 0 0 3 3 3 0 AAA domain HeLo PF14479.1 KFY03085.1 - 2e-39 135.5 0.4 2.4e-39 135.2 0.3 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation HET-s_218-289 PF11558.3 KFY03085.1 - 3e-09 36.7 2.5 7.1e-09 35.5 1.8 1.7 1 0 0 1 1 1 1 Het-s 218-289 DUF1192 PF06698.6 KFY03085.1 - 0.22 11.3 1.0 15 5.4 0.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) zf-C2H2_4 PF13894.1 KFY03086.1 - 3.5e-09 36.3 13.7 0.018 15.3 0.0 3.3 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KFY03086.1 - 1.1e-08 34.8 16.2 0.00077 19.6 1.8 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KFY03086.1 - 0.00074 19.6 11.0 0.74 10.2 0.3 4.1 4 0 0 4 4 4 3 Zinc-finger double domain Oxidored-like PF09791.4 KFY03086.1 - 0.0082 15.5 0.1 0.02 14.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal zf-C2H2_jaz PF12171.3 KFY03086.1 - 0.057 13.5 0.8 0.39 10.9 0.0 2.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KFY03086.1 - 0.13 12.1 0.4 0.13 12.1 0.3 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 KFY03086.1 - 0.83 9.8 7.2 2.6 8.2 2.2 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met2 PF12907.2 KFY03086.1 - 2 8.4 6.0 11 6.1 0.1 3.1 2 1 1 3 3 3 0 Zinc-binding WD40 PF00400.27 KFY03087.1 - 2e-162 522.0 36.5 5.1e-13 48.3 0.0 13.4 13 0 0 13 13 13 13 WD domain, G-beta repeat NACHT PF05729.7 KFY03087.1 - 6e-09 35.7 0.0 1.2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Cytochrom_D1 PF02239.11 KFY03087.1 - 1.2e-07 30.4 11.8 0.0059 14.9 0.1 5.4 1 1 3 5 5 5 4 Cytochrome D1 heme domain PD40 PF07676.7 KFY03087.1 - 2.4e-07 30.2 6.1 23 4.7 0.0 8.9 11 0 0 11 11 10 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 KFY03087.1 - 0.00023 20.4 0.0 87 2.5 0.0 6.5 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature AAA_16 PF13191.1 KFY03087.1 - 0.0008 19.4 0.2 0.004 17.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFY03087.1 - 0.003 17.6 0.0 0.014 15.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain HARP PF07443.8 KFY03087.1 - 0.0035 16.6 0.4 36 3.8 0.0 4.8 4 0 0 4 4 4 0 HepA-related protein (HARP) DUF374 PF04028.8 KFY03087.1 - 0.0055 15.9 0.7 52 3.1 0.0 6.1 4 3 5 9 9 9 0 Domain of unknown function (DUF374) MarR_2 PF12802.2 KFY03087.1 - 0.014 15.0 0.4 0.044 13.4 0.3 1.8 1 0 0 1 1 1 0 MarR family AAA_19 PF13245.1 KFY03087.1 - 0.026 14.2 0.0 0.11 12.3 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 KFY03087.1 - 0.064 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KFY03087.1 - 0.07 13.9 0.0 0.17 12.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KFY03087.1 - 0.08 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase HET-s_218-289 PF11558.3 KFY03087.1 - 1.2 9.1 3.6 21 5.1 0.0 4.6 6 1 0 6 6 6 0 Het-s 218-289 SIR2 PF02146.12 KFY03088.1 - 3.3e-16 59.5 0.0 6.8e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Sir2 family Peptidase_C48 PF02902.14 KFY03088.1 - 1e-10 41.6 0.1 5.1e-10 39.3 0.0 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain FAD_binding_8 PF08022.7 KFY03088.1 - 2.2e-09 37.1 0.0 5.8e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KFY03088.1 - 0.0023 17.8 0.0 0.0099 15.7 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Daxx PF03344.10 KFY03089.1 - 0.0028 16.2 28.1 0.0028 16.2 19.5 2.1 2 0 0 2 2 2 2 Daxx Family CENP-T PF15511.1 KFY03089.1 - 7 5.7 49.0 2.7 7.1 12.8 2.2 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T DUF3723 PF12520.3 KFY03092.1 - 1.8e-109 366.5 0.0 3.5e-100 335.9 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) Pkinase PF00069.20 KFY03093.1 - 3e-09 36.4 0.0 2.6e-08 33.3 0.0 2.2 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY03093.1 - 3.1e-08 33.0 0.0 9.6e-08 31.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase TraP PF07296.6 KFY03095.1 - 0.19 10.6 0.6 0.41 9.5 0.1 1.7 2 0 0 2 2 2 0 TraP protein FUSC_2 PF13515.1 KFY03095.1 - 0.29 11.0 21.6 1.5 8.7 1.6 3.3 1 1 2 3 3 3 0 Fusaric acid resistance protein-like F-box-like_2 PF13013.1 KFY03096.1 - 0.11 12.2 0.1 0.23 11.1 0.1 1.6 1 1 0 1 1 1 0 F-box-like domain NACHT PF05729.7 KFY03097.1 - 4.1e-06 26.5 0.0 8.2e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KFY03097.1 - 0.00046 20.3 0.1 0.0018 18.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain CAP_N PF01213.14 KFY03097.1 - 0.011 14.9 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal AAA_17 PF13207.1 KFY03097.1 - 0.038 14.8 0.1 0.27 12.0 0.0 2.4 2 2 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 KFY03097.1 - 0.084 11.8 0.0 1 8.2 0.0 1.9 1 1 1 2 2 2 0 KAP family P-loop domain DUF3338 PF11819.3 KFY03097.1 - 0.11 11.9 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) F-box PF00646.28 KFY03100.1 - 0.00047 19.7 0.6 0.0011 18.5 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFY03100.1 - 0.0012 18.5 0.6 0.0024 17.5 0.4 1.6 1 0 0 1 1 1 1 F-box-like BDHCT PF08072.6 KFY03100.1 - 0.0064 16.5 0.7 0.6 10.2 0.1 2.4 2 0 0 2 2 2 2 BDHCT (NUC031) domain MFS_1 PF07690.11 KFY03103.1 - 8.2e-31 106.9 31.0 1.1e-30 106.5 21.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY03103.1 - 6.7e-06 24.9 11.1 6.7e-06 24.9 7.7 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KFY03103.1 - 2.9e-05 22.4 4.6 4.2e-05 21.9 3.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Adaptin_binding PF10199.4 KFY03109.1 - 0.0002 21.6 0.6 0.00033 20.9 0.1 1.6 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 HABP4_PAI-RBP1 PF04774.10 KFY03109.1 - 0.47 10.9 4.7 1.1 9.8 3.3 1.5 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family FAD_binding_7 PF03441.9 KFY03110.1 - 1.6e-95 319.4 0.2 2.3e-95 319.0 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KFY03110.1 - 1.5e-40 138.6 0.0 2.4e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Homeobox PF00046.24 KFY03111.1 - 5e-20 70.8 3.5 9.6e-20 69.9 2.4 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KFY03111.1 - 0.0001 21.8 0.2 0.0001 21.8 0.1 1.9 2 0 0 2 2 2 1 Homeobox KN domain VCBS PF13517.1 KFY03115.1 - 4.1e-20 71.8 17.6 1.3e-09 38.2 1.2 5.3 3 1 2 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 KFY03115.1 - 8.5e-06 25.3 0.4 0.033 13.6 0.0 3.3 3 1 1 4 4 4 2 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.18 KFY03115.1 - 0.0023 17.5 0.8 0.0023 17.5 0.6 4.7 5 0 0 5 5 5 3 FG-GAP repeat WD40 PF00400.27 KFY03116.1 - 4.6e-14 51.6 1.3 4e-05 23.3 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_3 PF13570.1 KFY03116.1 - 0.00055 20.1 1.4 1.3 9.4 0.0 4.0 3 1 1 4 4 4 1 PQQ-like domain PQQ_2 PF13360.1 KFY03116.1 - 0.00099 18.6 0.2 0.17 11.3 0.1 2.5 1 1 0 1 1 1 1 PQQ-like domain Peptidase_C65 PF10275.4 KFY03137.1 - 1.4e-49 168.6 0.0 8e-49 166.1 0.0 1.9 1 1 0 1 1 1 1 Peptidase C65 Otubain Fungal_trans PF04082.13 KFY03142.1 - 2.9e-29 101.7 0.7 6.1e-29 100.6 0.2 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain HMG_box PF00505.14 KFY03142.1 - 5.3e-16 58.6 0.5 1.3e-15 57.4 0.4 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFY03142.1 - 8.4e-14 51.7 0.7 1.9e-13 50.5 0.5 1.6 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.25 KFY03142.1 - 2.1e-09 37.4 0.0 5e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFY03142.1 - 4.9e-05 23.0 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_5 PF14887.1 KFY03142.1 - 0.042 13.6 0.2 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box 5 C1_2 PF03107.11 KFY03142.1 - 0.11 12.6 0.1 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 C1 domain Fungal_trans PF04082.13 KFY03143.1 - 4.3e-09 35.6 0.4 7.1e-09 34.9 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY03144.1 - 0.0047 16.8 6.8 0.0078 16.0 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDC27 PF09507.5 KFY03144.1 - 0.096 11.8 2.0 0.11 11.6 1.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CAF-1_p150 PF11600.3 KFY03144.1 - 0.79 9.0 3.7 0.95 8.8 2.5 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ecl1 PF12855.2 KFY03145.1 - 6.3e-10 38.1 2.2 9.5e-10 37.6 1.5 1.2 1 0 0 1 1 1 1 Life-span regulatory factor DUF329 PF03884.9 KFY03145.1 - 0.0014 18.0 3.9 0.0035 16.8 2.8 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF329) DUF581 PF04570.9 KFY03145.1 - 0.0094 15.2 4.0 0.025 13.8 2.8 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF581) zf-FCS PF06467.9 KFY03145.1 - 0.13 11.9 1.4 0.38 10.4 0.9 1.8 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif MAGP PF05507.6 KFY03147.1 - 0.14 12.0 4.3 0.2 11.4 3.0 1.5 1 0 0 1 1 1 0 Microfibril-associated glycoprotein (MAGP) MFS_1 PF07690.11 KFY03149.1 - 8.7e-10 37.8 52.6 2.4e-08 33.1 36.0 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KFY03149.1 - 3.2 7.6 10.0 2.8 7.7 0.0 3.4 3 0 0 3 3 3 0 MFS_1 like family Peptidase_M3 PF01432.15 KFY03152.1 - 1.2e-153 512.5 0.0 1.4e-153 512.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 KFY03152.1 - 0.17 11.9 0.1 0.32 11.0 0.1 1.4 1 0 0 1 1 1 0 Effector protein SWIRM PF04433.12 KFY03153.1 - 5.2e-12 45.7 0.1 4.2e-11 42.8 0.0 2.3 2 0 0 2 2 2 1 SWIRM domain ZZ PF00569.12 KFY03153.1 - 1e-09 37.7 7.2 1.9e-09 36.9 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 KFY03153.1 - 4.9e-08 32.9 0.1 1.7e-06 27.9 0.0 2.9 3 0 0 3 3 3 1 Myb-like DNA-binding domain GerPC PF10737.4 KFY03154.1 - 0.00036 20.3 5.2 0.00046 20.0 3.2 1.4 1 1 0 1 1 1 1 Spore germination protein GerPC DUF2939 PF11159.3 KFY03154.1 - 0.0012 18.9 5.5 1.5 9.0 0.2 3.3 1 1 2 3 3 3 2 Protein of unknown function (DUF2939) DUF668 PF05003.7 KFY03154.1 - 0.0096 16.1 11.6 0.53 10.5 1.2 3.1 1 1 2 3 3 3 2 Protein of unknown function (DUF668) DUF45 PF01863.12 KFY03154.1 - 0.048 13.4 8.2 0.056 13.2 0.3 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF45 Vps39_2 PF10367.4 KFY03154.1 - 0.056 13.6 9.2 0.24 11.5 0.2 3.3 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 2 RHD3 PF05879.7 KFY03154.1 - 0.058 11.3 9.9 0.075 10.9 6.9 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Band_7 PF01145.20 KFY03154.1 - 0.22 11.4 2.2 0.96 9.3 1.5 2.1 1 1 0 1 1 1 0 SPFH domain / Band 7 family DUF3618 PF12277.3 KFY03154.1 - 0.24 11.4 3.0 0.17 11.9 0.3 2.1 2 0 0 2 2 1 0 Protein of unknown function (DUF3618) FHIPEP PF00771.15 KFY03154.1 - 0.25 9.6 5.9 0.14 10.4 2.7 1.4 1 1 0 1 1 1 0 FHIPEP family DUF445 PF04286.7 KFY03154.1 - 0.26 10.7 13.8 0.24 10.8 7.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) XH PF03469.9 KFY03154.1 - 0.46 10.1 13.3 0.53 9.9 2.8 2.4 1 1 1 2 2 2 0 XH domain Aha1_N PF09229.6 KFY03154.1 - 0.61 9.9 12.0 0.36 10.6 1.3 2.9 1 1 1 2 2 2 0 Activator of Hsp90 ATPase, N-terminal YpjP PF14005.1 KFY03154.1 - 1.1 9.0 7.9 5.5 6.7 1.3 2.9 1 1 2 3 3 3 0 YpjP-like protein Spore_II_R PF09551.5 KFY03154.1 - 1.6 8.8 10.2 8.1 6.4 2.1 2.7 1 1 3 4 4 4 0 Stage II sporulation protein R (spore_II_R) SRP54_N PF02881.14 KFY03154.1 - 2.1 8.5 11.1 13 5.9 1.2 3.2 1 1 1 2 2 2 0 SRP54-type protein, helical bundle domain DUF4410 PF14366.1 KFY03154.1 - 2.1 8.0 11.1 5.4 6.7 1.5 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4410) DUF2924 PF11149.3 KFY03154.1 - 2.4 8.1 9.4 1.6 8.7 1.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2924) DUF4297 PF14130.1 KFY03154.1 - 2.4 8.0 12.9 0.83 9.5 4.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4297) WASH-7_mid PF14744.1 KFY03154.1 - 2.5 6.8 9.2 2.4 6.9 1.4 2.1 1 1 1 2 2 2 0 WASH complex subunit 7 Tim44 PF04280.10 KFY03154.1 - 2.7 7.9 6.1 4 7.3 1.2 2.4 1 1 1 2 2 2 0 Tim44-like domain DUF3313 PF11769.3 KFY03154.1 - 3.1 7.1 7.4 8 5.7 0.5 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3313) Trigger_C PF05698.9 KFY03154.1 - 6.8 6.5 23.8 2.2 8.0 1.3 3.3 1 1 2 3 3 3 0 Bacterial trigger factor protein (TF) C-terminus DASH_Dam1 PF08653.5 KFY03154.1 - 9.5 6.0 6.7 4 7.2 0.1 3.1 3 1 0 3 3 3 0 DASH complex subunit Dam1 DUF1049 PF06305.6 KFY03155.1 - 0.016 14.7 0.7 0.016 14.7 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF2781 PF10914.3 KFY03156.1 - 5.9e-29 100.7 10.8 6.7e-29 100.6 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DUF981 PF06168.6 KFY03157.1 - 0.067 12.9 0.0 0.092 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF981) ATPase_gene1 PF09527.5 KFY03157.1 - 0.29 10.9 4.2 0.27 11.0 0.7 2.3 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit (ATPase_gene1) DUF3425 PF11905.3 KFY03158.1 - 9.3e-29 100.0 1.0 1.6e-28 99.2 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KFY03158.1 - 3.5 7.6 7.6 5.5 7.0 5.3 1.3 1 0 0 1 1 1 0 bZIP transcription factor Pyr_redox PF00070.22 KFY03159.1 - 6.5e-13 48.8 1.0 5.6e-10 39.4 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFY03159.1 - 1.1e-11 45.0 0.0 2.4e-11 43.9 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFY03159.1 - 1.9e-07 31.3 0.1 0.00041 20.4 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFY03159.1 - 4.4e-05 22.5 0.3 0.017 14.0 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) adh_short PF00106.20 KFY03160.1 - 3.8e-15 56.1 0.0 9.5e-15 54.9 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFY03160.1 - 8.4e-06 25.5 0.0 2.1e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KFY03160.1 - 2.2e-05 24.3 0.0 0.00014 21.6 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 KFY03160.1 - 0.082 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Nucleoporin_C PF03177.9 KFY03161.1 - 2.1e-119 399.7 0.7 2.6e-119 399.3 0.5 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KFY03161.1 - 1.5e-94 317.1 0.3 3.6e-94 315.9 0.2 1.6 2 0 0 2 2 2 1 Nup133 N terminal like Pkinase PF00069.20 KFY03161.1 - 5.6e-69 232.1 0.0 1.1e-68 231.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY03161.1 - 8.6e-33 113.4 0.0 1.6e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KFY03161.1 - 8.5e-07 29.4 0.2 2.4e-06 27.9 0.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KFY03161.1 - 0.0011 18.0 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF3802 PF12290.3 KFY03161.1 - 0.059 13.6 0.4 0.16 12.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3802) Ferric_reduct PF01794.14 KFY03171.1 - 1.6e-16 60.5 17.4 1.6e-16 60.5 12.1 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KFY03171.1 - 7.7e-16 57.8 0.0 1.7e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KFY03171.1 - 2e-11 44.0 0.0 3.4e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.1 KFY03171.1 - 0.51 10.5 18.2 0.45 10.6 1.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) Ctr PF04145.10 KFY03172.1 - 3.7e-26 91.9 7.3 5.4e-26 91.3 5.1 1.3 1 0 0 1 1 1 1 Ctr copper transporter family DUF2583 PF10762.4 KFY03172.1 - 1.8 8.7 6.7 0.65 10.1 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) COesterase PF00135.23 KFY03173.1 - 2.3e-91 307.1 0.0 2.9e-91 306.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFY03173.1 - 3.3e-05 23.5 0.1 0.00046 19.8 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 KFY03174.1 - 9.8e-84 281.9 0.0 1e-63 215.9 0.0 3.0 2 1 1 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.8 KFY03174.1 - 4e-08 33.1 0.0 7.5e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.4 KFY03174.1 - 0.0052 16.0 0.2 0.018 14.3 0.1 1.9 2 1 0 2 2 2 1 Esterase PHB depolymerase ABM PF03992.11 KFY03176.1 - 7.5e-05 22.6 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Cupin_5 PF06172.6 KFY03177.1 - 9.6e-21 74.1 0.0 1.3e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily (DUF985) COesterase PF00135.23 KFY03178.1 - 2.2e-85 287.3 0.6 1e-79 268.7 0.5 2.1 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KFY03178.1 - 6.4e-10 38.9 0.0 1.1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFY03178.1 - 0.00095 18.9 0.1 0.0023 17.6 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Oxidored_FMN PF00724.15 KFY03179.1 - 3.1e-42 144.7 0.0 6.7e-42 143.6 0.0 1.4 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 KFY03179.1 - 0.01 15.1 0.0 0.88 8.8 0.0 2.4 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel DUF849 PF05853.7 KFY03179.1 - 0.072 11.9 0.0 12 4.6 0.0 2.7 2 1 0 2 2 2 0 Prokaryotic protein of unknown function (DUF849) Vps35 PF03635.12 KFY03180.1 - 0 1027.8 5.1 0 1027.5 3.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Bromodomain PF00439.20 KFY03181.1 - 4.3e-24 84.2 0.3 1.1e-23 82.9 0.2 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.19 KFY03181.1 - 1.7e-08 34.4 0.0 3.5e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFY03181.1 - 4.1e-08 33.2 0.1 9e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Proteasom_Rpn13 PF04683.8 KFY03183.1 - 2.1e-28 98.2 0.0 3.3e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor SNF5 PF04855.7 KFY03184.1 - 1.2e-85 286.9 0.0 1.9e-85 286.2 0.0 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Ribosomal_L6e PF01159.14 KFY03184.1 - 6.6e-36 122.8 0.3 6.6e-36 122.8 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L6e GATA PF00320.22 KFY03184.1 - 7.8e-05 21.9 3.2 0.0002 20.6 2.2 1.7 1 0 0 1 1 1 1 GATA zinc finger Ribosomal_L7Ae PF01248.21 KFY03185.1 - 5.9e-23 80.1 0.0 6.7e-23 80.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Aminotran_3 PF00202.16 KFY03188.1 - 4.9e-73 245.9 0.0 6.1e-73 245.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF2838 PF10998.3 KFY03189.1 - 1.8e-47 159.7 8.4 1.8e-47 159.7 5.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) DUF1640 PF07798.6 KFY03189.1 - 0.5 10.3 1.9 0.34 10.9 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) Not3 PF04065.10 KFY03189.1 - 1.9 7.7 5.5 0.32 10.2 1.3 1.5 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Val_tRNA-synt_C PF10458.4 KFY03189.1 - 4.4 7.4 6.8 25 5.0 2.8 2.5 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm SMC_N PF02463.14 KFY03190.1 - 1.2e-57 194.6 11.2 5.2e-56 189.3 7.7 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KFY03190.1 - 2.3e-26 92.0 0.0 2e-25 89.0 0.0 2.8 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 KFY03190.1 - 4.4e-10 40.2 22.0 4.4e-10 40.2 15.3 6.0 2 2 2 4 4 1 1 AAA domain AAA_21 PF13304.1 KFY03190.1 - 7.6e-10 39.2 1.1 1.2e-05 25.4 0.0 4.0 4 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 KFY03190.1 - 2.3e-08 33.4 0.0 5.2e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 KFY03190.1 - 4.1e-06 26.2 30.3 0.017 14.3 4.0 4.6 3 1 0 4 4 4 3 Reovirus sigma C capsid protein SbcCD_C PF13558.1 KFY03190.1 - 0.0027 17.5 0.0 0.015 15.1 0.0 2.4 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit IncA PF04156.9 KFY03190.1 - 0.0053 16.3 11.5 0.0053 16.3 8.0 7.4 3 2 4 7 7 6 3 IncA protein DUF3584 PF12128.3 KFY03190.1 - 1.3 6.2 99.3 0.22 8.8 4.1 4.5 3 1 0 4 4 4 0 Protein of unknown function (DUF3584) Myosin_tail_1 PF01576.14 KFY03190.1 - 2 6.0 119.8 0.027 12.2 25.0 5.3 3 2 2 5 5 5 0 Myosin tail AAA_13 PF13166.1 KFY03190.1 - 4.4 5.6 101.1 0.014 13.8 10.1 6.4 3 2 3 6 6 6 0 AAA domain AAA_22 PF13401.1 KFY03190.1 - 7.2 6.7 9.0 9.8 6.3 0.0 4.7 5 1 1 6 6 5 0 AAA domain WD40 PF00400.27 KFY03191.1 - 3.5e-34 115.4 6.3 6e-07 29.0 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KFY03191.1 - 1.8e-07 31.0 0.0 0.0092 15.7 0.0 3.3 2 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A DUF3425 PF11905.3 KFY03191.1 - 0.052 13.4 0.2 0.28 11.0 0.2 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3425) Arf PF00025.16 KFY03192.1 - 4.9e-64 214.7 0.0 8.4e-64 213.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF3336 PF11815.3 KFY03192.1 - 1e-50 170.9 4.6 1.7e-50 170.2 3.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KFY03192.1 - 3.3e-19 69.6 0.2 7.5e-19 68.4 0.1 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase G-alpha PF00503.15 KFY03192.1 - 5.1e-10 38.5 0.0 3.3e-07 29.3 0.0 2.3 2 0 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KFY03192.1 - 7.7e-08 31.7 0.0 1.5e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KFY03192.1 - 5.5e-07 30.0 0.0 1.4e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFY03192.1 - 3.3e-06 27.0 0.0 7.2e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 KFY03192.1 - 6e-06 25.7 0.0 1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KFY03192.1 - 6.1e-05 22.2 0.0 9.9e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF876 PF05936.7 KFY03192.1 - 0.097 11.1 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF876) GTP_EFTU PF00009.22 KFY03192.1 - 0.098 12.0 0.0 1.2 8.5 0.0 2.2 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain DUF2347 PF09804.4 KFY03193.1 - 6.1e-100 334.1 0.0 7.8e-100 333.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 KFY03193.1 - 3.7e-43 147.6 0.0 7.1e-43 146.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.5 KFY03193.1 - 3.8e-05 23.3 0.0 9.1e-05 22.1 0.0 1.6 1 1 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KFY03193.1 - 0.001 17.6 0.0 0.014 13.8 0.0 2.3 2 1 0 2 2 2 1 Transport protein Avl9 Hormone_6 PF00236.13 KFY03194.1 - 0.25 11.1 0.1 0.25 11.1 0.1 2.1 2 0 0 2 2 2 0 Glycoprotein hormone Mucin PF01456.12 KFY03194.1 - 9.3 6.0 43.6 2.7 7.7 10.1 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein RRM_1 PF00076.17 KFY03195.1 - 3.6e-19 68.1 0.0 5e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY03195.1 - 3.6e-16 58.8 0.0 5.6e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFY03195.1 - 4.1e-12 45.7 0.0 5.6e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1793 PF08760.6 KFY03196.1 - 1.4e-72 243.0 0.0 3e-72 242.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF2457 PF10446.4 KFY03197.1 - 3.8e-161 536.8 38.3 3.8e-161 536.8 26.5 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF2457) CDC45 PF02724.9 KFY03197.1 - 5.1 5.0 27.8 3.1 5.7 1.1 2.3 2 0 0 2 2 2 0 CDC45-like protein POT1 PF02765.12 KFY03201.1 - 0.00067 19.5 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 IF4E PF01652.13 KFY03203.1 - 7.8e-52 175.1 0.1 1e-51 174.7 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Peptidase_C48 PF02902.14 KFY03204.1 - 2e-32 112.5 0.0 4.4e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain PgaD PF13994.1 KFY03204.1 - 0.71 9.3 0.1 1.6 8.2 0.1 1.5 1 0 0 1 1 1 0 PgaD-like protein F-box-like PF12937.2 KFY03205.1 - 3.6e-06 26.5 0.8 3.6e-06 26.5 0.6 2.4 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.2 KFY03205.1 - 0.063 12.9 3.2 7.1 6.3 0.1 3.5 2 1 0 3 3 3 0 Leucine Rich repeats (2 copies) zf-CW PF07496.10 KFY03205.1 - 0.16 11.6 1.5 14 5.4 0.0 2.4 2 0 0 2 2 2 0 CW-type Zinc Finger AIG2 PF06094.7 KFY03208.1 - 9e-15 55.0 0.0 1.9e-14 53.9 0.0 1.6 1 1 0 1 1 1 1 AIG2-like family Chitin_bind_3 PF03067.10 KFY03211.1 - 0.0043 17.3 0.0 0.012 15.8 0.0 1.7 2 0 0 2 2 2 1 Chitin binding domain DUF3433 PF11915.3 KFY03212.1 - 3.4e-38 129.7 19.5 2.8e-25 88.2 1.9 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) RR_TM4-6 PF06459.7 KFY03212.1 - 0.45 10.3 0.3 0.72 9.6 0.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4064 PF13273.1 KFY03212.1 - 0.98 9.5 10.8 2.8 8.1 0.2 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF4064) UPF0029 PF01205.14 KFY03213.1 - 9.7e-31 105.7 0.0 1.5e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 KFY03213.1 - 5.7e-08 32.6 0.0 3.3e-07 30.1 0.0 2.1 1 1 0 1 1 1 1 RWD domain alpha-hel2 PF14456.1 KFY03213.1 - 0.018 13.8 0.2 0.025 13.3 0.1 1.2 1 0 0 1 1 1 0 Alpha-helical domain 2 AMP-binding PF00501.23 KFY03216.1 - 2.6e-15 55.7 0.1 2.2e-09 36.2 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Hepatitis_core PF00906.15 KFY03216.1 - 0.13 11.9 0.1 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Hepatitis core antigen DUF3435 PF11917.3 KFY03223.1 - 4.6e-07 28.9 4.7 1.2e-06 27.5 1.7 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) MFS_1 PF07690.11 KFY03225.1 - 3.7e-27 94.9 48.2 9.4e-26 90.3 30.1 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFY03225.1 - 7.7e-20 70.6 15.8 2.3e-19 69.0 11.0 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KFY03225.1 - 2.7e-13 49.3 1.7 2.7e-13 49.3 1.2 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter FAD_binding_3 PF01494.14 KFY03226.1 - 1.7e-20 73.4 0.1 3.8e-20 72.2 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KFY03226.1 - 2.7e-06 27.3 1.1 6e-06 26.1 0.8 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFY03226.1 - 1.8e-05 23.8 6.4 0.0009 18.2 2.1 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFY03226.1 - 2e-05 23.6 1.1 3.1e-05 23.0 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KFY03226.1 - 6.2e-05 22.9 0.2 0.00014 21.8 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KFY03226.1 - 0.0047 16.5 0.6 0.0092 15.5 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 KFY03226.1 - 0.0061 15.6 1.3 0.0097 15.0 0.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFY03226.1 - 0.0075 16.6 2.1 0.017 15.5 1.5 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFY03226.1 - 0.046 12.5 2.6 0.066 12.0 1.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 KFY03226.1 - 0.067 12.2 0.1 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 KFY03226.1 - 0.073 13.1 0.3 0.12 12.3 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFY03226.1 - 0.093 11.1 1.5 0.15 10.4 1.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Fungal_trans PF04082.13 KFY03227.1 - 2.7e-20 72.3 0.0 5.4e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY03227.1 - 4e-08 33.0 10.5 8.7e-08 31.9 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APG6 PF04111.7 KFY03227.1 - 2 7.3 6.8 0.52 9.3 1.7 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 Reo_sigmaC PF04582.7 KFY03227.1 - 2.9 6.9 5.5 0.87 8.7 0.3 2.4 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Glyco_hydro_61 PF03443.9 KFY03228.1 - 4.8e-42 144.2 0.0 5.9e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 COesterase PF00135.23 KFY03231.1 - 2.1e-78 264.3 0.1 5.1e-78 263.0 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFY03231.1 - 4.2e-12 46.0 0.0 8.3e-12 45.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFY03231.1 - 0.07 12.8 1.1 0.11 12.2 0.4 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family TauD PF02668.11 KFY03233.1 - 3.5e-15 56.3 1.5 1.9e-14 53.9 1.0 1.9 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KFY03233.1 - 0.02 13.8 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 CsiD CP_ATPgrasp_2 PF14403.1 KFY03233.1 - 0.043 12.4 0.0 0.065 11.8 0.0 1.3 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 DUF3824 PF12868.2 KFY03235.1 - 1.2 10.0 7.1 2 9.3 4.9 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF3748 PF12566.3 KFY03236.1 - 0.057 13.3 0.0 0.066 13.1 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3748) F-box PF00646.28 KFY03238.1 - 0.0043 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFY03238.1 - 0.037 13.7 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 F-box-like NIF PF03031.13 KFY03241.1 - 1.1e-39 135.6 0.0 1.6e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Kinesin PF00225.18 KFY03243.1 - 5.7e-115 383.5 0.8 9.5e-115 382.8 0.2 1.6 2 0 0 2 2 2 1 Kinesin motor domain Herpes_UL14 PF03580.9 KFY03243.1 - 0.011 15.4 2.7 0.026 14.2 1.9 1.5 1 0 0 1 1 1 0 Herpesvirus UL14-like protein AAA_33 PF13671.1 KFY03243.1 - 0.022 14.6 0.4 0.077 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain CGI-121 PF08617.5 KFY03244.1 - 8.7e-50 168.5 0.0 1.2e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Fungal_trans PF04082.13 KFY03245.1 - 2e-21 76.0 0.1 3.2e-21 75.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY03245.1 - 4e-08 33.0 8.8 7e-08 32.2 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_dh PF01619.13 KFY03247.1 - 2.4e-11 43.1 0.2 2.8e-11 42.9 0.2 1.1 1 0 0 1 1 1 1 Proline dehydrogenase LRR_4 PF12799.2 KFY03250.1 - 0.00086 18.8 0.3 0.0042 16.6 0.2 2.1 1 1 0 1 1 1 1 Leucine Rich repeats (2 copies) Terpene_synth_C PF03936.11 KFY03254.1 - 2e-10 40.3 0.0 2.4e-10 40.1 0.0 1.0 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain HMG_CoA_synt_C PF08540.5 KFY03255.1 - 5.4e-96 321.3 1.0 8.8e-96 320.6 0.7 1.3 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KFY03255.1 - 4.1e-78 260.9 0.0 5.9e-78 260.3 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal p450 PF00067.17 KFY03256.1 - 7.6e-63 212.6 0.0 8.6e-63 212.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KFY03257.1 - 1.4e-25 89.7 0.0 2.8e-24 85.5 0.0 2.2 2 1 0 2 2 2 2 Cytochrome P450 Methyltransf_23 PF13489.1 KFY03262.1 - 3.5e-19 69.1 0.0 5.2e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY03262.1 - 1.2e-12 47.6 0.0 1.3e-11 44.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY03262.1 - 2.9e-12 46.9 0.0 1.2e-11 44.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY03262.1 - 1.3e-10 41.5 0.0 2.1e-09 37.7 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY03262.1 - 2.1e-10 41.1 0.1 2.4e-09 37.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY03262.1 - 4.2e-06 27.0 0.0 9.8e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFY03262.1 - 0.00012 22.1 0.0 0.0004 20.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KFY03262.1 - 0.00021 20.4 0.0 0.00037 19.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_16 PF10294.4 KFY03262.1 - 0.00025 20.5 0.2 0.0032 16.9 0.0 2.3 2 1 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 KFY03262.1 - 0.00078 18.8 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 KFY03262.1 - 0.0034 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 KFY03262.1 - 0.017 14.2 0.0 0.094 11.8 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 KFY03262.1 - 0.026 13.6 0.0 0.046 12.8 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.8 KFY03262.1 - 0.028 13.5 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pol_alpha_B_N PF08418.5 KFY03280.1 - 7.6e-61 205.8 0.4 1e-60 205.4 0.3 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 KFY03280.1 - 7.7e-07 28.5 0.0 1.2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CRAL_TRIO PF00650.15 KFY03281.1 - 4.3e-39 133.5 0.0 6.3e-39 133.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain TRAPP PF04051.11 KFY03281.1 - 8.7e-37 125.9 0.0 1.3e-36 125.4 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CRAL_TRIO_N PF03765.10 KFY03281.1 - 3e-07 30.4 0.0 6.4e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KFY03281.1 - 0.0042 16.9 0.0 0.0069 16.3 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Apc13p PF05839.6 KFY03282.1 - 4.9e-32 109.7 0.7 7.4e-32 109.1 0.2 1.5 2 0 0 2 2 2 1 Apc13p protein zf-RING_2 PF13639.1 KFY03283.1 - 4.9e-05 23.0 3.2 7.6e-05 22.4 1.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFY03283.1 - 0.03 14.3 1.1 0.03 14.3 0.7 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4279 PF14106.1 KFY03283.1 - 0.046 13.5 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) FANCL_C PF11793.3 KFY03283.1 - 0.074 13.0 4.4 3.4 7.7 1.3 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 KFY03283.1 - 8 6.5 6.9 1.1 9.3 1.2 2.3 3 0 0 3 3 3 0 RING-variant domain Kinesin PF00225.18 KFY03284.1 - 2.6e-112 374.8 0.0 2.6e-112 374.8 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain DUF87 PF01935.12 KFY03284.1 - 0.63 9.8 0.0 0.63 9.8 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function DUF87 PUL PF08324.6 KFY03285.1 - 1.7e-36 125.3 0.1 2.8e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 KFY03285.1 - 1e-32 112.9 0.0 1.6e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 KFY03285.1 - 2e-14 53.1 0.0 3.8e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KFY03285.1 - 0.0061 16.7 1.0 0.051 13.7 0.7 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.1 KFY03285.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein GDA1_CD39 PF01150.12 KFY03286.1 - 1.7e-93 313.5 0.0 2.2e-93 313.1 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family VHS PF00790.14 KFY03288.1 - 2e-41 140.9 1.1 2.3e-40 137.4 0.0 2.4 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 KFY03288.1 - 7.1e-16 57.8 2.8 1.4e-15 56.9 1.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 KFY03288.1 - 0.0013 18.0 15.8 0.03 13.8 0.6 3.5 3 0 0 3 3 3 2 Ubiquitin interaction motif zf-DHHC PF01529.15 KFY03288.1 - 0.043 13.2 0.5 0.13 11.6 0.3 1.8 1 0 0 1 1 1 0 DHHC palmitoyltransferase NUDIX PF00293.23 KFY03289.1 - 6.8e-16 58.1 0.1 2e-15 56.6 0.1 1.7 1 1 0 1 1 1 1 NUDIX domain Phage_XkdX PF09693.5 KFY03290.1 - 0.033 13.6 0.0 0.047 13.2 0.0 1.2 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) PBP1_TM PF14812.1 KFY03290.1 - 0.39 11.0 2.1 0.59 10.4 1.4 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_hydro_75 PF07335.6 KFY03291.1 - 1.4e-36 125.7 0.2 2e-36 125.2 0.1 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 CarbpepA_inh PF02977.10 KFY03291.1 - 0.71 9.4 26.2 3.2 7.4 5.8 3.0 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor Kelch_1 PF01344.20 KFY03292.1 - 2.7e-39 132.4 8.9 8.6e-09 34.8 0.0 7.4 7 0 0 7 7 7 5 Kelch motif Kelch_6 PF13964.1 KFY03292.1 - 3.3e-33 112.4 17.5 2.6e-08 33.6 0.1 7.1 2 2 5 7 7 7 6 Kelch motif Kelch_3 PF13415.1 KFY03292.1 - 1.5e-22 79.1 16.8 3e-06 27.2 0.0 6.8 6 1 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.1 KFY03292.1 - 3.8e-22 77.7 17.1 7.7e-07 28.7 0.0 7.7 7 2 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.10 KFY03292.1 - 1.2e-16 59.6 4.1 0.001 18.7 0.0 6.3 7 1 0 7 7 7 5 Kelch motif Kelch_5 PF13854.1 KFY03292.1 - 2.3e-16 59.3 8.2 0.0034 17.3 0.0 6.3 6 0 0 6 6 6 6 Kelch motif DUF1668 PF07893.8 KFY03292.1 - 6.6e-05 22.1 0.1 0.33 10.0 0.0 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF1668) YlaH PF14036.1 KFY03293.1 - 1.9 8.6 7.4 0.092 12.8 0.6 2.2 3 0 0 3 3 3 0 YlaH-like protein PALP PF00291.20 KFY03294.1 - 2.7e-54 184.4 2.7 4.9e-54 183.6 1.9 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.23 KFY03294.1 - 2.3e-24 85.9 0.1 5e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFY03294.1 - 6.1e-17 61.3 0.0 7.2e-15 54.7 0.0 2.5 2 0 0 2 2 2 1 Peptidase dimerisation domain Clathrin-link PF09268.5 KFY03294.1 - 0.099 11.7 0.5 0.25 10.4 0.0 2.0 2 0 0 2 2 2 0 Clathrin, heavy-chain linker Fungal_trans_2 PF11951.3 KFY03295.1 - 5.2e-14 51.6 0.3 1.4e-13 50.2 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY03295.1 - 6e-07 29.2 13.5 1e-06 28.5 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2296 PF10058.4 KFY03297.1 - 9.9e-20 70.0 0.1 1.6e-19 69.3 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DEAD PF00270.24 KFY03299.1 - 3.7e-18 65.5 0.0 6.7e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KFY03299.1 - 4.7e-08 33.0 0.1 1.9e-06 27.8 0.0 3.3 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KFY03299.1 - 6.3e-07 29.1 0.1 1.3e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 KFY03299.1 - 0.014 14.6 0.0 0.24 10.5 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Abhydrolase_6 PF12697.2 KFY03303.1 - 6.8e-12 45.7 0.2 1.1e-11 45.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY03303.1 - 5.2e-05 22.9 0.0 6.9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFY03303.1 - 7.3e-05 22.5 0.0 0.00034 20.3 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 KFY03303.1 - 0.043 13.4 0.0 0.092 12.3 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase GED PF02212.13 KFY03304.1 - 0.068 13.0 1.0 0.32 10.8 0.7 1.9 1 1 0 1 1 1 0 Dynamin GTPase effector domain Abhydrolase_6 PF12697.2 KFY03311.1 - 5e-10 39.6 0.0 6.4e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY03311.1 - 9.5e-06 25.3 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFY03311.1 - 7.6e-05 22.4 0.0 0.0001 22.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 KFY03311.1 - 0.01 15.4 0.3 0.016 14.8 0.1 1.3 1 1 0 1 1 1 0 Serine hydrolase Transferase PF02458.10 KFY03312.1 - 4e-14 51.9 0.0 6.1e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 Transferase family ZZ PF00569.12 KFY03314.1 - 2e-12 46.4 7.0 3.3e-12 45.7 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.27 KFY03314.1 - 9.2e-08 30.8 12.8 2.4e-05 23.2 0.4 3.5 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 KFY03314.1 - 2.9e-07 30.5 1.8 0.0027 17.8 0.3 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KFY03314.1 - 2.1e-05 23.9 8.1 0.00019 21.0 0.6 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 KFY03314.1 - 0.00029 20.3 5.0 0.027 14.0 0.1 3.1 2 1 1 3 3 3 2 EF-hand domain pair C1_3 PF07649.7 KFY03314.1 - 0.02 14.9 5.2 0.033 14.2 3.6 1.4 1 0 0 1 1 1 0 C1-like domain zf-B_box PF00643.19 KFY03314.1 - 0.078 12.8 5.5 0.15 11.9 3.8 1.5 1 0 0 1 1 1 0 B-box zinc finger GATA PF00320.22 KFY03314.1 - 3.3 7.1 5.5 1.2 8.5 0.1 2.9 2 0 0 2 2 2 0 GATA zinc finger Diphthamide_syn PF01866.12 KFY03317.1 - 3e-52 177.7 0.0 3.5e-51 174.2 0.0 2.0 2 0 0 2 2 2 1 Putative diphthamide synthesis protein Fn_bind PF02986.9 KFY03317.1 - 1.2 8.7 4.0 0.29 10.6 0.4 1.8 2 0 0 2 2 2 0 Fibronectin binding repeat RTA1 PF04479.8 KFY03318.1 - 9e-52 175.8 6.2 1.4e-51 175.2 4.3 1.2 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.13 KFY03319.1 - 0.0022 17.8 2.8 0.0045 16.8 1.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFY03319.1 - 0.0028 16.3 0.2 0.0042 15.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 KFY03320.1 - 1e-20 74.6 0.1 1.9e-20 73.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY03320.1 - 9.6e-14 51.4 0.0 1.3e-12 47.7 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFY03320.1 - 7e-09 35.5 0.0 1.9e-08 34.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFY03320.1 - 0.0029 16.8 0.8 0.29 10.3 0.0 2.6 3 0 0 3 3 3 1 Prolyl oligopeptidase family Glyco_hydro_43 PF04616.9 KFY03320.1 - 0.005 15.9 1.0 0.0089 15.1 0.7 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KFY03320.1 - 0.022 14.1 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain UPF0227 PF05728.7 KFY03320.1 - 0.072 12.7 0.0 0.82 9.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydrolase_4 PF08386.5 KFY03320.1 - 0.081 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Hydrolase_4 PF12146.3 KFY03320.1 - 0.13 12.1 0.1 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 Putative lysophospholipase PGAP1 PF07819.8 KFY03320.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Kelch_5 PF13854.1 KFY03322.1 - 8.8e-09 35.1 11.7 1.6e-07 31.0 0.2 4.5 4 0 0 4 4 4 2 Kelch motif Herpes_gE PF02480.11 KFY03322.1 - 0.0027 16.0 0.0 0.0049 15.1 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E VSP PF03302.8 KFY03322.1 - 0.12 10.9 0.1 0.19 10.2 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein FAD_binding_4 PF01565.18 KFY03324.1 - 1.2e-23 83.0 0.0 1.9e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFY03324.1 - 0.0046 16.8 0.0 0.021 14.7 0.0 2.2 1 0 0 1 1 1 1 Berberine and berberine like COesterase PF00135.23 KFY03325.1 - 2.6e-69 234.3 0.0 4.2e-69 233.6 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFY03325.1 - 1e-07 31.7 0.0 2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFY03325.1 - 0.027 13.7 0.0 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2424 PF10340.4 KFY03325.1 - 0.086 11.4 0.0 0.45 9.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Fungal_trans_2 PF11951.3 KFY03326.1 - 1.2e-05 24.0 0.6 1.7e-05 23.6 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY03326.1 - 1.8e-05 24.5 9.7 1.8e-05 24.5 6.7 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1175 PF06672.6 KFY03327.1 - 0.0017 17.7 0.1 0.0029 17.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1175) Glyco_hydro_43 PF04616.9 KFY03328.1 - 4.7e-68 229.3 0.7 5.8e-68 229.0 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Grp1_Fun34_YaaH PF01184.14 KFY03330.1 - 1.9e-87 291.9 20.4 2.3e-87 291.6 14.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2748 PF10871.3 KFY03330.1 - 0.15 10.4 0.1 0.21 9.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) Glyco_hydro_61 PF03443.9 KFY03331.1 - 3e-50 171.0 0.0 3.5e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DAO PF01266.19 KFY03332.1 - 1.2e-21 77.0 0.7 4.7e-21 75.0 0.5 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFY03332.1 - 5.9e-05 23.0 0.5 0.00023 21.1 0.4 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFY03332.1 - 0.00033 20.6 0.0 0.00048 20.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFY03332.1 - 0.00039 19.3 0.1 0.00061 18.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KFY03332.1 - 0.0004 20.7 0.2 0.001 19.4 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFY03332.1 - 0.0014 17.8 0.0 0.0025 16.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 KFY03332.1 - 0.0022 16.9 0.2 0.0029 16.5 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.11 KFY03332.1 - 0.0046 16.4 0.2 0.0086 15.5 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 KFY03332.1 - 0.01 14.3 0.2 0.015 13.8 0.1 1.1 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 KFY03332.1 - 0.013 15.1 0.1 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KFY03332.1 - 0.032 14.5 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 KFY03332.1 - 0.068 12.2 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 KFY03332.1 - 0.073 13.1 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 KFY03332.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 KFY03332.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 KFY03332.1 - 0.14 11.4 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.7 KFY03332.1 - 0.15 10.9 0.1 0.27 10.1 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein TPR_12 PF13424.1 KFY03334.1 - 3.9e-16 58.7 0.4 2e-06 27.6 0.0 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 KFY03334.1 - 7e-08 32.1 0.0 0.21 11.5 0.0 5.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KFY03334.1 - 3.6e-06 27.2 0.2 0.84 10.0 0.0 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFY03334.1 - 1.6e-05 25.4 0.0 2.1 9.1 0.0 4.3 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFY03334.1 - 0.00083 19.7 0.6 1.7 9.5 0.1 5.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFY03334.1 - 0.00088 18.8 0.0 0.13 11.8 0.0 3.1 1 1 0 2 2 2 1 TPR repeat TPR_7 PF13176.1 KFY03334.1 - 0.008 15.9 0.1 0.55 10.1 0.0 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 KFY03334.1 - 0.037 14.1 0.0 1.2 9.3 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KFY03334.1 - 0.06 13.8 0.1 78 4.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF202 PF02656.10 KFY03335.1 - 1.3 9.2 4.2 17 5.7 0.1 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Abhydrolase_6 PF12697.2 KFY03336.1 - 6.5e-31 107.9 0.0 8.1e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY03336.1 - 8.5e-22 77.8 0.1 9.5e-18 64.5 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFY03336.1 - 5.2e-15 55.4 0.0 7.7e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1057 PF06342.7 KFY03336.1 - 5e-06 25.5 0.0 6.8e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Ndr PF03096.9 KFY03336.1 - 9e-06 24.3 0.0 2.3e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Ndr family Hydrolase_4 PF12146.3 KFY03336.1 - 2.1e-05 24.2 0.0 4.2e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 KFY03336.1 - 0.00019 21.0 0.0 0.00029 20.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.6 KFY03336.1 - 0.0022 17.0 0.1 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 KFY03336.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 KFY03336.1 - 0.036 13.6 0.0 0.062 12.8 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 KFY03336.1 - 0.061 12.7 0.0 0.097 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative esterase BAAT_C PF08840.6 KFY03336.1 - 0.095 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 KFY03336.1 - 0.14 11.3 0.1 4 6.6 0.0 2.3 1 1 0 1 1 1 0 Dienelactone hydrolase family Thioesterase PF00975.15 KFY03336.1 - 0.15 12.2 0.0 0.25 11.5 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain UPF0227 PF05728.7 KFY03336.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) MFS_1 PF07690.11 KFY03338.1 - 7.2e-37 126.9 35.9 4.3e-34 117.7 12.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY03338.1 - 1.6e-09 36.8 5.3 1.6e-09 36.8 3.6 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter Sulfatase PF00884.18 KFY03339.1 - 1.1e-62 211.9 0.3 1.5e-62 211.5 0.2 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KFY03339.1 - 0.0032 16.8 0.1 0.26 10.5 0.0 2.3 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase dUTPase PF00692.14 KFY03340.1 - 7.8e-13 48.0 0.0 1.1e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 dUTPase DCD PF06559.6 KFY03340.1 - 0.0009 17.7 0.0 0.0039 15.6 0.0 1.7 1 1 0 1 1 1 1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) HMG_box PF00505.14 KFY03345.1 - 0.0025 18.0 0.3 0.0093 16.2 0.0 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFY03345.1 - 0.011 16.1 0.2 0.042 14.2 0.0 1.9 1 1 1 2 2 2 0 HMG-box domain Ecl1 PF12855.2 KFY03346.1 - 2.2e-05 23.6 0.2 4.4e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Life-span regulatory factor DUF221 PF02714.10 KFY03348.1 - 2.6e-55 187.5 12.4 3.7e-35 121.3 2.7 2.2 2 0 0 2 2 2 2 Domain of unknown function DUF221 DUF3779 PF12621.3 KFY03348.1 - 2.7e-12 46.3 0.0 4.4e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Phosphate metabolism protein AA_permease_2 PF13520.1 KFY03350.1 - 6.1e-36 123.8 53.0 9.6e-36 123.2 36.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFY03350.1 - 3.5e-17 61.9 45.4 5.5e-17 61.2 31.4 1.2 1 0 0 1 1 1 1 Amino acid permease PhyH PF05721.8 KFY03352.1 - 1.1e-27 97.4 0.0 2e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans_2 PF11951.3 KFY03355.1 - 4.7e-06 25.4 1.4 4.7e-06 25.4 1.0 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain Amidohydro_1 PF01979.15 KFY03356.1 - 1.8e-20 73.8 0.1 2e-10 40.8 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 KFY03356.1 - 1.4e-14 54.8 1.2 2.3e-14 54.0 0.8 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KFY03356.1 - 1.4e-10 40.8 0.2 3.5e-10 39.5 0.1 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KFY03356.1 - 3.5e-06 26.4 0.8 0.0026 17.0 0.0 2.6 2 1 1 3 3 3 2 Amidohydrolase family Cu_amine_oxid PF01179.15 KFY03357.1 - 1.1e-162 541.4 0.0 1.4e-162 541.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 KFY03357.1 - 1.6e-12 47.3 0.0 3.1e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 KFY03357.1 - 9.7e-06 25.5 0.0 2.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Abhydrolase_5 PF12695.2 KFY03369.1 - 2.1e-15 56.7 0.4 3e-15 56.2 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFY03369.1 - 1.7e-14 54.2 0.5 3.5e-14 53.2 0.4 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFY03369.1 - 2.2e-08 33.6 0.0 4.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KFY03369.1 - 2.2e-07 30.7 0.2 2.4e-06 27.2 0.1 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KFY03369.1 - 3.1e-05 23.6 0.0 4.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 KFY03369.1 - 0.0013 18.1 4.6 0.0023 17.3 1.0 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Ser_hydrolase PF06821.8 KFY03369.1 - 0.013 15.0 0.5 0.025 14.2 0.1 1.5 2 0 0 2 2 2 0 Serine hydrolase DUF1072 PF06380.6 KFY03369.1 - 0.016 14.8 0.2 0.042 13.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1072) Lipase_3 PF01764.20 KFY03369.1 - 0.018 14.6 0.2 0.039 13.5 0.1 1.6 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.11 KFY03369.1 - 0.033 13.6 0.7 0.34 10.3 0.1 2.3 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase Cutinase PF01083.17 KFY03369.1 - 0.047 13.4 0.1 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 Cutinase DUF676 PF05057.9 KFY03369.1 - 0.081 12.1 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) NMT_C PF02799.10 KFY03370.1 - 3.6e-77 258.0 0.0 5.1e-77 257.5 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 KFY03370.1 - 5.1e-77 257.0 0.0 8e-77 256.3 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 KFY03370.1 - 0.012 15.4 0.0 0.084 12.7 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KFY03370.1 - 0.018 15.2 0.0 0.039 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Molydop_binding PF01568.16 KFY03370.1 - 0.037 13.8 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain RhoGAP PF00620.22 KFY03370.1 - 0.041 13.4 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 RhoGAP domain DUF427 PF04248.7 KFY03370.1 - 0.054 13.1 0.1 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF427) Herpes_BLLF1 PF05109.8 KFY03371.1 - 0.27 9.1 19.0 0.36 8.7 13.2 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Dynamin_N PF00350.18 KFY03378.1 - 1.8e-18 66.8 0.8 3.8e-18 65.8 0.3 1.8 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KFY03378.1 - 5e-13 48.4 0.0 8.3e-11 41.1 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 KFY03378.1 - 7.3e-07 29.1 0.2 5.5e-06 26.3 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFY03378.1 - 2.8e-05 23.4 0.0 0.0016 17.7 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 KFY03378.1 - 0.0021 18.5 0.5 0.016 15.7 0.0 2.6 2 1 0 3 3 3 1 Miro-like protein GED PF02212.13 KFY03378.1 - 0.046 13.6 0.0 0.2 11.6 0.0 2.2 1 1 0 1 1 1 0 Dynamin GTPase effector domain GTP_EFTU PF00009.22 KFY03378.1 - 0.049 13.0 0.4 0.8 9.1 0.5 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Ras PF00071.17 KFY03378.1 - 0.069 12.5 0.2 0.8 9.0 0.0 2.4 2 0 0 2 2 2 0 Ras family Arf PF00025.16 KFY03378.1 - 0.13 11.4 2.3 0.19 10.9 0.2 2.3 3 1 0 3 3 3 0 ADP-ribosylation factor family Flocculin_t3 PF13928.1 KFY03379.1 - 0.016 15.3 9.5 0.016 15.3 6.6 3.1 1 1 2 3 3 3 0 Flocculin type 3 repeat Glyco_hydro_4 PF02056.11 KFY03379.1 - 0.019 14.3 0.4 0.026 13.8 0.3 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase DUF1138 PF06592.8 KFY03379.1 - 0.084 12.9 1.4 0.15 12.0 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1138) Asn_synthase PF00733.16 KFY03381.1 - 4.9e-69 232.6 0.0 8.2e-69 231.9 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase UQ_con PF00179.21 KFY03381.1 - 9.2e-48 161.2 0.1 4e-47 159.1 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme GATase_7 PF13537.1 KFY03381.1 - 2.3e-35 121.0 0.0 4e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KFY03381.1 - 2.8e-29 101.7 0.0 4.5e-28 97.8 0.0 2.2 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 KFY03381.1 - 2e-09 36.9 0.0 3.4e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 KFY03381.1 - 0.0009 18.0 0.0 0.02 13.6 0.0 2.5 1 1 2 3 3 3 1 Glutamine amidotransferases class-II NAD_synthase PF02540.12 KFY03381.1 - 0.0027 16.6 0.0 0.0076 15.1 0.0 1.7 1 1 0 1 1 1 1 NAD synthase Prok-E2_B PF14461.1 KFY03381.1 - 0.041 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic E2 family B BRX_N PF13713.1 KFY03381.1 - 0.13 11.7 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain RWD PF05773.17 KFY03381.1 - 0.14 12.0 0.1 2.1 8.2 0.0 2.6 3 0 0 3 3 3 0 RWD domain IBR PF01485.16 KFY03382.1 - 4.1e-05 23.3 65.5 0.00042 20.1 9.1 6.4 4 2 1 5 5 5 3 IBR domain zf-RING_2 PF13639.1 KFY03382.1 - 0.0033 17.2 4.6 0.0033 17.2 3.2 6.3 5 2 2 7 7 7 1 Ring finger domain Fer2_3 PF13085.1 KFY03382.1 - 0.02 14.7 0.9 0.02 14.7 0.6 3.3 3 1 1 4 4 4 0 2Fe-2S iron-sulfur cluster binding domain DUF1712 PF08217.6 KFY03383.1 - 2.3e-15 55.8 0.0 3.8e-14 51.8 0.0 2.1 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Formyl_trans_N PF00551.14 KFY03384.1 - 3.6e-22 78.7 0.0 5.7e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase WD40 PF00400.27 KFY03385.1 - 2.4e-48 160.3 23.8 2.4e-11 43.0 0.0 7.4 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 KFY03385.1 - 3.4e-07 28.8 7.6 0.047 11.8 0.1 4.9 3 1 1 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.6 KFY03385.1 - 0.00064 19.4 0.8 0.056 13.1 0.0 3.2 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 KFY03385.1 - 0.0036 15.5 0.0 0.0062 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) Coatomer_WDAD PF04053.9 KFY03385.1 - 0.01 14.6 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region PQQ_2 PF13360.1 KFY03385.1 - 0.051 13.0 0.1 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain Hira PF07569.6 KFY03385.1 - 0.082 12.1 0.4 5.6 6.1 0.0 3.0 1 1 2 3 3 3 0 TUP1-like enhancer of split Spc7 PF08317.6 KFY03386.1 - 0.085 11.5 1.0 0.17 10.4 0.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.1 KFY03386.1 - 0.1 11.7 0.7 0.38 9.9 0.3 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.3 KFY03386.1 - 0.25 11.0 1.9 0.28 10.9 0.1 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding KLRAQ PF10205.4 KFY03386.1 - 1.2 9.2 7.5 7.9 6.5 0.3 3.0 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein IncA PF04156.9 KFY03386.1 - 5.6 6.5 6.1 0.8 9.2 0.7 2.0 2 0 0 2 2 2 0 IncA protein UPF0542 PF15086.1 KFY03387.1 - 0.013 15.2 0.1 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 SUR7 PF06687.7 KFY03388.1 - 1.3e-30 106.5 12.3 1.6e-30 106.2 8.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KFY03388.1 - 0.017 14.7 4.3 3.9 7.1 2.0 2.5 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4131 PF13567.1 KFY03388.1 - 0.039 13.3 4.8 2 7.7 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) UPF0233 PF06781.7 KFY03388.1 - 0.36 10.4 5.0 3.1 7.4 0.0 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0233) PMP22_Claudin PF00822.15 KFY03388.1 - 3.5 7.2 8.1 33 4.0 5.0 2.5 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family HILPDA PF15220.1 KFY03388.1 - 6.5 6.8 7.0 0.41 10.6 0.7 2.1 2 1 0 2 2 2 0 Hypoxia-inducible lipid droplet-associated AAA_16 PF13191.1 KFY03389.1 - 9.1e-08 32.2 0.0 3.1e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KFY03389.1 - 1.5e-06 28.0 0.0 3.7e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 NACHT domain NTPase_1 PF03266.10 KFY03389.1 - 2.1e-05 24.3 0.0 5.3e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 NTPase AAA_17 PF13207.1 KFY03389.1 - 0.00044 21.0 0.1 0.0017 19.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KFY03389.1 - 0.0025 17.9 0.0 0.006 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 KFY03389.1 - 0.0026 17.4 0.0 0.013 15.2 0.0 2.0 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_19 PF13245.1 KFY03389.1 - 0.0027 17.4 0.0 0.015 15.0 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 KFY03389.1 - 0.0033 17.3 0.0 0.0065 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KFY03389.1 - 0.0074 16.0 0.1 0.12 12.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KFY03389.1 - 0.01 15.6 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KFY03389.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 KFY03389.1 - 0.012 14.4 0.0 0.022 13.5 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Arch_ATPase PF01637.13 KFY03389.1 - 0.012 15.3 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase cobW PF02492.14 KFY03389.1 - 0.015 14.7 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KTI12 PF08433.5 KFY03389.1 - 0.016 14.4 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.1 KFY03389.1 - 0.034 14.4 0.0 0.074 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KFY03389.1 - 0.035 13.5 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain KaiC PF06745.8 KFY03389.1 - 0.046 12.8 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 KaiC UFD1 PF03152.9 KFY03390.1 - 1.4e-26 92.6 0.0 4.1e-21 74.8 0.0 3.3 3 1 0 3 3 3 3 Ubiquitin fusion degradation protein UFD1 Methyltransf_22 PF13383.1 KFY03391.1 - 7e-23 81.4 0.0 8.9e-23 81.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 KFY03391.1 - 3.1e-05 23.9 0.0 4.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain GCIP PF13324.1 KFY03392.1 - 2.1e-06 27.1 0.6 4.5e-06 26.0 0.2 1.7 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting WHG PF13305.1 KFY03392.1 - 0.085 13.4 0.5 1.5 9.4 0.0 2.9 3 1 0 3 3 3 0 WHG domain Actin PF00022.14 KFY03393.1 - 6.3e-100 334.3 0.0 7.8e-100 334.0 0.0 1.0 1 0 0 1 1 1 1 Actin BPL_N PF09825.4 KFY03394.1 - 5.5e-138 459.7 0.0 7.1e-138 459.3 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 KFY03394.1 - 2e-21 76.2 0.1 3.5e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 KFY03394.1 - 0.078 12.6 0.1 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain DUF2250 PF10007.4 KFY03394.1 - 0.19 11.6 0.0 0.58 10.1 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) Rtf2 PF04641.7 KFY03397.1 - 2.2e-57 194.2 1.5 2.6e-57 193.9 1.0 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 KFY03397.1 - 4.7e-05 22.8 0.2 0.0093 15.4 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 KFY03397.1 - 0.0082 15.8 1.2 0.021 14.5 0.1 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KFY03397.1 - 0.028 14.0 0.1 0.058 13.0 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFY03397.1 - 0.35 10.7 1.3 1.5 8.7 0.0 2.3 3 0 0 3 3 3 0 Ring finger domain FAT PF02259.18 KFY03398.1 - 3.9e-131 437.2 1.6 3.9e-131 437.2 1.1 1.9 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.3 KFY03398.1 - 4.6e-63 211.9 4.7 2.2e-59 199.9 0.9 4.2 4 0 0 4 4 4 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 KFY03398.1 - 3e-60 203.6 0.4 5.4e-60 202.7 0.3 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 KFY03398.1 - 9.2e-43 144.4 2.4 1.7e-42 143.5 0.1 2.8 2 0 0 2 2 2 1 Rapamycin binding domain HEAT_2 PF13646.1 KFY03398.1 - 2.4e-21 75.7 9.9 0.00034 20.8 0.1 9.0 5 2 4 10 10 10 7 HEAT repeats HEAT PF02985.17 KFY03398.1 - 2.2e-17 61.5 11.9 0.00039 20.2 0.0 11.1 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.1 KFY03398.1 - 6e-14 52.0 12.4 1e-05 25.8 0.0 10.5 9 3 3 12 12 10 2 HEAT-like repeat FATC PF02260.15 KFY03398.1 - 9.9e-13 47.2 0.1 2.5e-12 46.0 0.1 1.7 1 0 0 1 1 1 1 FATC domain Adaptin_N PF01602.15 KFY03398.1 - 3.5e-07 28.9 9.7 0.029 12.7 5.4 4.8 3 1 0 3 3 3 1 Adaptin N terminal region CLASP_N PF12348.3 KFY03398.1 - 9.3e-06 25.1 1.2 0.23 10.7 0.0 5.2 5 1 0 5 5 5 1 CLASP N terminal Apc3 PF12895.2 KFY03398.1 - 0.0047 17.0 2.2 4.9 7.3 0.0 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 Sec7_N PF12783.2 KFY03398.1 - 0.099 12.0 4.8 5 6.5 0.0 4.0 3 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_7 PF13176.1 KFY03398.1 - 0.1 12.4 4.2 5.8 6.9 0.2 4.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Aldo_ket_red PF00248.16 KFY03399.1 - 3.1e-61 206.7 0.0 3.9e-61 206.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pex24p PF06398.6 KFY03401.1 - 4.5e-96 321.7 0.5 5.3e-96 321.5 0.4 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PAP_assoc PF03828.14 KFY03402.1 - 9.4e-11 41.5 0.0 2.6e-10 40.1 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KFY03402.1 - 7.6e-07 29.3 0.0 1.8e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain LsmAD PF06741.8 KFY03403.1 - 6.9e-24 83.7 4.4 6.9e-24 83.7 3.1 2.4 2 0 0 2 2 2 1 LsmAD domain AIP3 PF03915.8 KFY03405.1 - 5.9e-161 536.1 1.9 5.9e-161 536.1 1.3 1.7 2 0 0 2 2 2 1 Actin interacting protein 3 PPI_Ypi1 PF07491.6 KFY03405.1 - 1.6e-23 82.0 0.4 4.3e-23 80.6 0.3 1.8 1 0 0 1 1 1 1 Protein phosphatase inhibitor Lectin_N PF03954.9 KFY03405.1 - 0.02 14.3 2.7 0.031 13.6 0.2 2.6 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain FliL PF03748.9 KFY03405.1 - 0.029 14.3 0.4 0.093 12.7 0.3 1.8 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL DUF1664 PF07889.7 KFY03405.1 - 1.3 8.8 4.9 4.6 7.0 0.2 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) HbrB PF08539.6 KFY03406.1 - 3.5e-50 169.9 0.0 5.2e-50 169.3 0.0 1.3 1 0 0 1 1 1 1 HbrB-like Gon7 PF08738.5 KFY03407.1 - 8.9e-15 54.5 7.1 3.2e-13 49.5 4.9 2.0 1 1 0 1 1 1 1 Gon7 family Vps39_1 PF10366.4 KFY03408.1 - 1.4e-35 121.5 0.0 1.3e-34 118.4 0.0 2.7 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 KFY03408.1 - 6.6e-30 103.4 0.0 2.5e-29 101.6 0.0 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 KFY03408.1 - 5.4e-17 62.1 0.0 3.3e-16 59.5 0.0 2.0 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.15 KFY03408.1 - 7.6e-05 22.3 0.5 0.00079 19.0 0.1 2.8 2 0 0 2 2 2 1 Region in Clathrin and VPS TPR_1 PF00515.23 KFY03408.1 - 0.001 18.5 2.6 1.9 8.2 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFY03408.1 - 0.0011 19.5 1.2 0.15 12.7 0.3 3.8 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFY03408.1 - 0.0055 16.3 4.1 10 5.8 0.1 4.9 3 2 1 4 4 4 1 TPR repeat Apc3 PF12895.2 KFY03408.1 - 0.014 15.5 0.2 0.71 10.0 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KFY03408.1 - 0.028 14.3 2.0 16 5.4 0.1 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFY03408.1 - 0.064 13.6 4.9 3.7 7.9 0.6 3.8 4 2 0 4 4 4 0 Tetratricopeptide repeat LIM_bind PF01803.11 KFY03409.1 - 1.7e-79 266.3 0.4 1.7e-79 266.3 0.3 5.2 2 1 2 5 5 5 1 LIM-domain binding protein Abhydrolase_3 PF07859.8 KFY03410.1 - 1.6e-36 125.8 0.0 2.8e-25 89.1 0.0 2.5 1 1 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KFY03410.1 - 0.022 13.4 0.0 0.035 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) GET2 PF08690.5 KFY03411.1 - 9.2e-08 31.6 1.2 3.1e-07 29.9 0.9 1.9 1 1 0 1 1 1 1 GET complex subunit GET2 TRAM_LAG1_CLN8 PF03798.11 KFY03411.1 - 0.089 12.3 0.1 0.089 12.3 0.1 1.5 2 0 0 2 2 2 0 TLC domain zf-LYAR PF08790.6 KFY03413.1 - 0.92 9.2 3.8 11 5.8 0.2 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Aminotran_1_2 PF00155.16 KFY03414.1 - 5.9e-35 120.8 0.0 7.2e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KFY03414.1 - 0.021 13.0 0.0 0.038 12.2 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_17 PF00332.13 KFY03415.1 - 6.6e-09 35.2 4.9 7.6e-07 28.4 0.3 2.5 2 1 1 3 3 3 2 Glycosyl hydrolases family 17 Bromodomain PF00439.20 KFY03416.1 - 2e-36 123.7 4.6 1.1e-19 70.1 0.3 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 KFY03416.1 - 3.6e-15 55.7 0.9 3.6e-15 55.7 0.6 2.0 2 0 0 2 2 2 1 BAH domain HIT PF01230.18 KFY03418.1 - 2.3e-22 79.3 0.1 3.2e-22 78.9 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KFY03418.1 - 2.8e-13 50.1 0.0 4.5e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KFY03418.1 - 1.7e-05 24.4 0.0 2.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CSTF2_hinge PF14327.1 KFY03418.1 - 0.12 12.4 0.2 0.75 9.9 0.0 2.0 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 CRAL_TRIO PF00650.15 KFY03419.1 - 3.7e-40 137.0 0.0 6.2e-40 136.2 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFY03419.1 - 5.7e-14 51.9 0.0 1.5e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KFY03419.1 - 3e-08 33.6 0.0 7.4e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DASH_Dam1 PF08653.5 KFY03420.1 - 0.0064 16.2 0.4 0.0099 15.6 0.2 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 zf-C2H2_jaz PF12171.3 KFY03421.1 - 8.8e-11 41.6 1.1 2.6e-10 40.1 0.8 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.7 KFY03421.1 - 0.0012 18.3 0.2 0.0035 16.8 0.2 1.8 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_2 PF12756.2 KFY03421.1 - 0.0026 17.8 0.5 0.0059 16.7 0.3 1.5 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFY03421.1 - 0.05 13.8 0.9 0.14 12.4 0.6 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type CTNNB1_binding PF08347.6 KFY03421.1 - 0.056 13.6 0.6 0.081 13.1 0.4 1.2 1 0 0 1 1 1 0 N-terminal CTNNB1 binding Papo_T_antigen PF02380.10 KFY03421.1 - 0.37 10.7 0.0 0.37 10.7 0.0 2.0 2 1 1 3 3 3 0 T-antigen specific domain Aconitase PF00330.15 KFY03422.1 - 1.9e-175 583.8 0.0 4.3e-175 582.6 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KFY03422.1 - 2.5e-45 153.7 0.0 4.9e-45 152.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Rhomboid PF01694.17 KFY03423.1 - 1.5e-14 54.2 10.8 1.5e-14 54.2 7.5 2.0 2 0 0 2 2 2 1 Rhomboid family Nodulin-like PF06813.8 KFY03423.1 - 0.012 14.9 1.2 0.039 13.1 0.3 2.0 1 1 1 2 2 2 0 Nodulin-like Gaa1 PF04114.9 KFY03424.1 - 1.2e-101 340.9 7.6 2.3e-101 339.9 5.3 1.5 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component PCI PF01399.22 KFY03425.1 - 8.2e-09 35.7 0.0 1.8e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 PCI domain N6-adenineMlase PF10237.4 KFY03426.1 - 3e-54 183.0 0.1 9.1e-54 181.4 0.0 1.8 2 0 0 2 2 2 1 Probable N6-adenine methyltransferase NAD_binding_10 PF13460.1 KFY03426.1 - 1.1e-18 67.8 0.0 2.2e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFY03426.1 - 4.6e-17 62.0 0.0 6.9e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KFY03426.1 - 4.8e-15 55.6 0.1 9.1e-15 54.7 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFY03426.1 - 4.3e-11 42.0 0.0 9.1e-11 40.9 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KFY03426.1 - 5.2e-09 35.4 0.0 8.9e-08 31.3 0.0 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KFY03426.1 - 8.4e-06 24.8 0.8 0.00071 18.5 0.6 3.0 1 1 0 1 1 1 1 Male sterility protein Saccharop_dh PF03435.13 KFY03426.1 - 0.00024 20.2 0.0 0.00038 19.5 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 KFY03426.1 - 0.0028 17.6 0.0 0.016 15.1 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KFY03426.1 - 0.025 13.4 0.0 0.042 12.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.5 KFY03426.1 - 0.032 13.8 0.0 5.6 6.5 0.0 2.8 3 0 0 3 3 3 0 KR domain DDE_Tnp_1_3 PF13612.1 KFY03426.1 - 0.078 12.7 0.0 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain UCH PF00443.24 KFY03427.1 - 2.6e-56 190.6 5.2 3.5e-56 190.2 3.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFY03427.1 - 9.8e-32 110.5 6.3 1.4e-31 110.0 4.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KFY03427.1 - 0.00048 20.1 0.1 0.00048 20.1 0.0 2.8 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Lactamase_B PF00753.22 KFY03428.1 - 2.9e-19 69.5 1.1 5e-19 68.7 0.8 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFY03428.1 - 0.0002 20.9 0.1 0.00028 20.4 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KFY03428.1 - 0.022 14.4 0.1 0.037 13.7 0.1 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain I-set PF07679.11 KFY03429.1 - 0.00012 21.8 0.1 2.4 8.0 0.0 4.7 4 0 0 4 4 4 2 Immunoglobulin I-set domain DUF1918 PF08940.6 KFY03429.1 - 0.013 14.8 0.4 1.7 8.0 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1918) Peptidase_C12 PF01088.16 KFY03430.1 - 1.8e-59 200.5 0.0 4.1e-58 196.0 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 NPCBM_assoc PF10633.4 KFY03430.1 - 0.12 12.4 0.2 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase YccV-like PF08755.6 KFY03431.1 - 4.6e-24 84.2 0.2 8.8e-24 83.3 0.1 1.5 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 KFY03431.1 - 4.8e-16 58.6 0.0 9.5e-16 57.6 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 KFY03431.1 - 3.8e-09 36.1 0.4 1.2e-08 34.5 0.3 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFY03431.1 - 8.4e-05 22.1 0.0 0.00023 20.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 KFY03431.1 - 0.00055 20.2 0.7 0.0011 19.3 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A SPX PF03105.14 KFY03432.1 - 3.1e-43 148.5 0.2 3.1e-43 148.5 0.1 1.5 2 0 0 2 2 2 1 SPX domain zf-C3HC4_3 PF13920.1 KFY03432.1 - 4.3e-07 29.4 8.3 6.8e-07 28.8 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KFY03432.1 - 5.1e-07 29.4 11.5 5.1e-07 29.4 8.0 1.7 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFY03432.1 - 1.4e-06 27.8 12.7 2.7e-06 26.9 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFY03432.1 - 2.7e-06 27.1 10.9 5e-06 26.2 7.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KFY03432.1 - 5.4e-06 26.0 10.0 1e-05 25.1 6.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KFY03432.1 - 3.1e-05 23.9 12.9 5.8e-05 23.0 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KFY03432.1 - 0.0065 16.1 8.2 0.023 14.4 5.7 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 KFY03432.1 - 0.014 14.9 4.2 0.014 14.9 2.9 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain TerY-C PF15616.1 KFY03432.1 - 0.028 14.3 1.2 0.048 13.6 0.8 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-rbx1 PF12678.2 KFY03432.1 - 0.035 14.2 3.8 0.068 13.2 2.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger RdRP_1 PF00680.15 KFY03432.1 - 0.077 11.2 0.1 2.9 6.0 0.0 2.5 3 0 0 3 3 3 0 RNA dependent RNA polymerase zf-Apc11 PF12861.2 KFY03432.1 - 0.1 12.4 2.6 0.19 11.5 1.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1644 PF07800.7 KFY03432.1 - 0.13 12.1 3.4 0.94 9.3 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) zf-RING_6 PF14835.1 KFY03432.1 - 0.7 9.7 7.0 1 9.1 4.0 1.9 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-P11 PF03854.9 KFY03432.1 - 6 6.4 8.7 1.1e+02 2.3 6.3 2.2 1 1 1 2 2 2 0 P-11 zinc finger DnaJ PF00226.26 KFY03433.1 - 1.7e-25 88.5 0.4 4.5e-25 87.1 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 KFY03433.1 - 4.5e-09 36.1 3.0 4.5e-09 36.1 2.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KFY03433.1 - 4.2e-08 33.2 3.3 0.0014 18.6 0.5 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 KFY03433.1 - 8.1e-07 29.0 2.7 8.1e-07 29.0 1.9 2.8 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 KFY03433.1 - 0.0016 18.6 5.8 0.31 11.4 0.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type RPT PF13446.1 KFY03433.1 - 0.0023 17.2 0.1 0.0072 15.7 0.0 1.8 2 0 0 2 2 2 1 A repeated domain in UCH-protein zf-C2H2_6 PF13912.1 KFY03433.1 - 0.016 15.0 3.8 0.54 10.2 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4451 PF14616.1 KFY03433.1 - 0.48 10.1 4.4 11 5.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4451) DUF2387 PF09526.5 KFY03433.1 - 0.49 10.3 5.3 0.31 10.9 1.2 2.4 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) zf-C2H2_4 PF13894.1 KFY03433.1 - 0.99 9.8 3.4 23 5.6 0.2 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger PSCyt3 PF07627.6 KFY03433.1 - 2.1 8.2 5.6 0.78 9.6 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1588) Peptidase_C54 PF03416.14 KFY03434.1 - 1.1e-90 303.6 0.0 1.3e-90 303.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 G-patch PF01585.18 KFY03435.1 - 7.4e-11 41.6 2.1 9.8e-11 41.2 0.4 2.1 2 0 0 2 2 2 1 G-patch domain R3H PF01424.17 KFY03435.1 - 1.8e-10 40.3 0.0 4.8e-10 38.9 0.0 1.8 1 0 0 1 1 1 1 R3H domain Chromo PF00385.19 KFY03435.1 - 7.5e-05 22.3 0.0 0.00017 21.1 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain G-patch_2 PF12656.2 KFY03435.1 - 0.0013 18.5 2.5 0.0028 17.4 0.2 2.6 2 0 0 2 2 2 1 DExH-box splicing factor binding site Histone PF00125.19 KFY03436.1 - 2.2e-22 78.9 0.2 3.1e-22 78.4 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFY03436.1 - 9.9e-05 22.3 0.0 9.9e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KFY03436.1 - 0.00021 21.5 0.0 0.00036 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 KFY03436.1 - 0.0062 15.2 2.2 0.008 14.8 1.6 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein RP-C PF03428.8 KFY03436.1 - 0.0093 15.4 0.1 0.013 14.9 0.1 1.3 1 0 0 1 1 1 1 Replication protein C N-terminal domain DUF1018 PF06252.7 KFY03436.1 - 0.023 15.1 0.7 0.033 14.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Histone PF00125.19 KFY03437.1 - 8.2e-26 89.9 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KFY03437.1 - 1.2e-05 25.2 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Complex1_LYR PF05347.10 KFY03438.1 - 4.3e-09 36.0 1.2 6.2e-09 35.5 0.8 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KFY03438.1 - 6.5e-06 26.2 0.9 9.5e-06 25.7 0.6 1.3 1 0 0 1 1 1 1 Complex1_LYR-like 2-oxoacid_dh PF00198.18 KFY03439.1 - 7.2e-78 261.0 0.0 1e-77 260.5 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KFY03439.1 - 6e-17 61.0 1.3 1.1e-16 60.2 0.9 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 KFY03439.1 - 4.6e-05 22.7 2.0 0.00051 19.2 0.3 2.3 1 1 1 2 2 2 1 HlyD family secretion protein Ndc1_Nup PF09531.5 KFY03439.1 - 3 6.1 5.3 3.9 5.7 3.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2413 PF10310.4 KFY03439.1 - 5.5 5.6 12.5 7.5 5.2 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Ytp1 PF10355.4 KFY03440.1 - 5e-106 353.8 7.8 1.2e-105 352.6 5.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KFY03440.1 - 4.8e-30 103.2 14.1 1.2e-29 101.9 3.9 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF2427) K_oxygenase PF13434.1 KFY03440.1 - 7.1e-18 64.6 0.0 2.9e-13 49.4 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 KFY03440.1 - 2.4e-12 47.3 0.1 5.8e-07 29.7 0.0 3.3 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFY03440.1 - 2.5e-05 24.0 0.0 0.25 11.1 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding Shikimate_DH PF01488.15 KFY03440.1 - 0.0069 16.4 0.1 0.055 13.5 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 KFY03440.1 - 0.014 14.2 0.0 0.3 9.8 0.0 2.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KFY03440.1 - 0.021 14.6 0.0 0.72 9.6 0.0 2.4 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFY03440.1 - 0.082 11.8 0.0 0.19 10.6 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 KFY03440.1 - 0.085 12.5 0.0 0.59 9.8 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 KFY03440.1 - 0.14 11.7 0.0 2.9 7.5 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KNOX1 PF03790.8 KFY03440.1 - 0.19 11.1 1.1 7 6.0 0.5 2.6 2 0 0 2 2 2 0 KNOX1 domain DAO PF01266.19 KFY03440.1 - 0.31 9.8 2.3 4.2 6.1 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase SprT-like PF10263.4 KFY03443.1 - 4e-38 130.5 0.1 5.8e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 SprT-like family Peptidase_MA_2 PF13485.1 KFY03443.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Peptidase MA superfamily Glyco_hydro_72 PF03198.9 KFY03444.1 - 4.5e-139 462.7 2.9 1.3e-111 372.6 1.2 2.1 1 1 1 2 2 2 2 Glucanosyltransferase X8 PF07983.8 KFY03444.1 - 1.6e-26 92.5 7.3 1.6e-26 92.5 5.1 2.3 2 0 0 2 2 2 1 X8 domain Glucan_synthase PF02364.10 KFY03445.1 - 0 1467.5 0.0 0 1466.9 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KFY03445.1 - 2.1e-39 134.0 0.4 5e-39 132.8 0.3 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 GWT1 PF06423.7 KFY03450.1 - 9.5e-41 139.0 2.1 2.3e-40 137.8 1.4 1.7 1 0 0 1 1 1 1 GWT1 DUF1129 PF06570.6 KFY03450.1 - 0.12 11.6 1.3 0.74 9.0 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Glu-tRNAGln PF02686.10 KFY03451.1 - 0.044 13.5 0.1 8.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit FAD-oxidase_C PF02913.14 KFY03453.1 - 3.1e-56 190.4 0.2 3.1e-56 190.4 0.1 2.3 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KFY03453.1 - 2.1e-36 124.4 0.0 5e-36 123.2 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain Clr5 PF14420.1 KFY03453.1 - 1.4e-21 76.0 5.7 1.4e-21 76.0 3.9 2.4 3 0 0 3 3 3 1 Clr5 domain WD40 PF00400.27 KFY03453.1 - 0.051 13.4 0.1 1.7 8.6 0.0 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat Sensor PF13796.1 KFY03453.1 - 0.073 12.6 1.9 0.2 11.2 1.3 1.7 1 0 0 1 1 1 0 Putative sensor FMN_dh PF01070.13 KFY03454.1 - 4.3e-104 348.1 0.0 5.5e-104 347.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KFY03454.1 - 4.2e-14 52.1 0.0 1e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KFY03454.1 - 1.9e-07 30.3 0.2 3.7e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KFY03454.1 - 1.5e-05 24.1 0.1 0.00021 20.3 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 KFY03454.1 - 0.023 13.9 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein BPL_C PF02237.12 KFY03454.1 - 0.025 14.2 0.0 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain NMO PF03060.10 KFY03454.1 - 0.027 13.6 0.2 0.052 12.6 0.1 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.16 KFY03454.1 - 0.035 13.0 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase ThiG PF05690.9 KFY03454.1 - 0.051 12.6 0.0 6.7 5.6 0.0 2.3 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Ribul_P_3_epim PF00834.14 KFY03454.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family ATP11 PF06644.6 KFY03454.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 ATP11 protein adh_short_C2 PF13561.1 KFY03455.1 - 8.9e-20 71.4 0.1 1.3e-19 70.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFY03455.1 - 1.1e-18 67.7 2.8 1.5e-18 67.2 1.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFY03455.1 - 3e-06 27.0 2.9 1.2e-05 25.0 2.0 1.7 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KFY03455.1 - 0.062 13.3 0.1 0.22 11.6 0.2 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF1772 PF08592.6 KFY03456.1 - 0.00039 20.1 1.8 0.016 14.9 2.0 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF1772) DUF1932 PF09130.6 KFY03457.1 - 9.6e-19 66.8 0.1 2.2e-18 65.7 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.12 KFY03457.1 - 8.2e-07 29.3 0.1 1.8e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KFY03457.1 - 3e-05 23.8 0.0 4.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KFY03457.1 - 0.00093 18.3 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.4 KFY03457.1 - 0.016 14.9 0.2 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 Rossmann-like domain IlvN PF07991.7 KFY03457.1 - 0.034 13.5 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 KFY03457.1 - 0.083 12.5 0.1 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain INCA1 PF15142.1 KFY03458.1 - 0.031 14.0 0.1 0.091 12.5 0.0 1.8 2 0 0 2 2 2 0 INCA1 zf-RanBP PF00641.13 KFY03458.1 - 0.25 10.4 3.2 0.49 9.5 2.2 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 KFY03459.1 - 5.2e-17 61.2 0.0 8e-17 60.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY03459.1 - 4.2e-12 45.8 0.0 6.4e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KFY03459.1 - 1.2e-07 32.0 8.5 1.2e-07 32.0 5.9 3.3 3 1 1 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 KFY03459.1 - 9.9e-07 28.5 0.0 1.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY03465.1 - 3.3e-09 36.5 1.3 1.2e-08 34.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFY03465.1 - 8.8e-08 31.8 0.2 8.8e-08 31.8 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KFY03465.1 - 0.00017 21.1 5.0 0.00059 19.4 0.1 3.1 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFY03465.1 - 0.0023 17.6 0.0 0.012 15.4 0.0 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF1330 PF07045.6 KFY03465.1 - 0.038 13.8 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1330) RRM_3 PF08777.6 KFY03465.1 - 0.13 12.1 0.1 0.13 12.1 0.1 3.1 3 0 0 3 3 3 0 RNA binding motif DUF2937 PF11157.3 KFY03465.1 - 9.2 5.5 8.9 0.8 9.0 2.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) SWIRM PF04433.12 KFY03466.1 - 1.3e-34 118.1 0.1 2.8e-34 117.1 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 KFY03466.1 - 1.8e-06 27.8 0.1 4.2e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KFY03466.1 - 6.1e-05 23.0 0.0 0.00015 21.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ETF PF01012.16 KFY03467.1 - 8.6e-41 139.3 2.5 8.7e-41 139.3 0.6 1.7 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 KFY03467.1 - 7.9e-35 118.3 0.3 1.8e-34 117.1 0.2 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Pyr_redox_2 PF07992.9 KFY03468.1 - 3e-06 27.2 0.0 2.1e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFY03468.1 - 0.00034 20.7 0.0 0.014 15.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase PEGSRP PF07623.6 KFY03469.1 - 0.018 14.3 0.6 0.045 13.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) MutL_C PF08676.6 KFY03470.1 - 3.3e-23 81.8 0.0 7.5e-23 80.7 0.0 1.7 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 KFY03470.1 - 1.1e-18 66.7 0.0 3.3e-18 65.2 0.0 1.8 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KFY03470.1 - 2.5e-15 56.3 0.5 7.1e-14 51.6 0.1 3.1 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KFY03470.1 - 3.2e-12 46.1 1.0 5.4e-12 45.4 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ATP_synt_H PF05493.8 KFY03471.1 - 1.7e-26 92.0 2.8 1.9e-26 91.8 1.9 1.0 1 0 0 1 1 1 1 ATP synthase subunit H OppC_N PF12911.2 KFY03471.1 - 0.015 14.6 0.8 0.54 9.6 0.1 2.1 1 1 1 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF1129 PF06570.6 KFY03471.1 - 0.035 13.3 0.5 0.044 13.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Claudin_2 PF13903.1 KFY03471.1 - 0.046 13.4 1.7 0.051 13.2 1.2 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction YfhO PF09586.5 KFY03471.1 - 0.091 10.7 0.6 0.094 10.7 0.4 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO ABC2_membrane_2 PF12679.2 KFY03471.1 - 0.12 11.1 3.2 0.14 10.9 2.2 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Pox_A14 PF05767.7 KFY03471.1 - 0.17 11.8 0.9 0.22 11.5 0.6 1.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF4131 PF13567.1 KFY03471.1 - 0.36 10.2 2.7 0.37 10.1 1.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Arv1 PF04161.8 KFY03472.1 - 8.1e-19 68.3 0.0 1e-18 68.0 0.0 1.1 1 0 0 1 1 1 1 Arv1-like family DUF3419 PF11899.3 KFY03484.1 - 8.8e-83 278.1 0.0 1e-82 277.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) AAA_16 PF13191.1 KFY03484.1 - 0.073 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Cutinase PF01083.17 KFY03485.1 - 1.6e-53 181.1 8.4 1.9e-53 180.8 5.9 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 KFY03485.1 - 0.00012 21.5 0.1 0.00021 20.7 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain CBM_1 PF00734.13 KFY03485.1 - 0.026 14.2 13.3 0.026 14.2 9.2 4.0 4 1 1 5 5 5 0 Fungal cellulose binding domain Abhydrolase_6 PF12697.2 KFY03485.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Acyl-CoA_dh_1 PF00441.19 KFY03486.1 - 1.3e-29 103.2 0.9 1.9e-29 102.7 0.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KFY03486.1 - 2.5e-22 78.1 0.5 5.4e-22 77.0 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KFY03486.1 - 1.2e-19 70.9 0.0 2.7e-19 69.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KFY03486.1 - 0.0012 19.0 0.0 0.002 18.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CFEM PF05730.6 KFY03487.1 - 5.6e-10 38.8 14.2 9.2e-10 38.2 9.8 1.4 1 0 0 1 1 1 1 CFEM domain Pex14_N PF04695.8 KFY03487.1 - 5.9 6.9 7.2 15 5.6 5.0 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF566 PF04484.7 KFY03487.1 - 6 6.2 6.5 6.9 6.0 4.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) NUDIX PF00293.23 KFY03488.1 - 1.5e-10 40.8 0.0 2.8e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_1 PF00583.19 KFY03489.1 - 1.2e-08 34.8 0.0 1.8e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KFY03489.1 - 0.00038 20.1 0.0 0.00075 19.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KFY03489.1 - 0.023 14.8 0.0 0.048 13.7 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFY03489.1 - 0.025 14.7 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFY03489.1 - 0.079 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Grp1_Fun34_YaaH PF01184.14 KFY03490.1 - 4.2e-30 104.6 17.8 5.9e-30 104.1 12.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF1129 PF06570.6 KFY03490.1 - 0.25 10.6 5.9 0.15 11.3 3.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) DAD PF02109.11 KFY03490.1 - 0.43 10.6 8.3 0.17 11.9 4.2 1.5 1 1 0 1 1 1 0 DAD family DUF373 PF04123.8 KFY03490.1 - 4.5 6.1 11.0 5.9 5.7 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Septin PF00735.13 KFY03491.1 - 2.8e-32 111.8 0.0 3.7e-11 42.5 0.0 3.1 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.13 KFY03491.1 - 0.0029 17.0 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family G-alpha PF00503.15 KFY03491.1 - 0.034 12.8 0.0 0.034 12.8 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Miro PF08477.8 KFY03491.1 - 0.051 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 KFY03491.1 - 0.052 13.3 1.1 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Dynamin family Prefoldin PF02996.12 KFY03493.1 - 0.0009 18.8 2.4 0.0009 18.8 1.6 3.6 3 1 1 4 4 3 1 Prefoldin subunit MIS13 PF08202.6 KFY03493.1 - 0.012 14.6 5.7 0.09 11.8 3.9 2.0 1 1 0 1 1 1 0 Mis12-Mtw1 protein family Reo_sigmaC PF04582.7 KFY03493.1 - 0.028 13.6 3.6 0.031 13.4 0.4 2.1 2 1 0 2 2 2 0 Reovirus sigma C capsid protein Fez1 PF06818.10 KFY03493.1 - 0.032 14.2 12.5 0.066 13.2 8.7 1.6 1 0 0 1 1 1 0 Fez1 AAA_13 PF13166.1 KFY03493.1 - 0.047 12.1 7.3 0.056 11.8 5.0 1.3 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 KFY03493.1 - 0.12 11.9 22.9 0.13 11.8 8.2 2.6 2 1 0 2 2 2 0 IncA protein ERM PF00769.14 KFY03493.1 - 0.29 10.6 15.2 0.25 10.8 1.6 2.4 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Baculo_PEP_C PF04513.7 KFY03493.1 - 0.29 10.9 3.5 0.71 9.6 0.6 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4613 PF15390.1 KFY03493.1 - 0.3 9.2 3.3 0.35 8.9 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Rootletin PF15035.1 KFY03493.1 - 0.37 10.7 13.0 4.9 7.0 9.0 2.6 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF1664 PF07889.7 KFY03493.1 - 0.37 10.6 6.0 4.3 7.1 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.6 KFY03493.1 - 0.66 9.7 16.4 0.48 10.2 3.8 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Syntaxin PF00804.20 KFY03493.1 - 0.77 9.9 7.4 0.69 10.1 2.8 2.7 1 1 1 2 2 2 0 Syntaxin MerR-DNA-bind PF09278.6 KFY03493.1 - 0.78 10.1 16.5 7.3 7.0 2.3 3.6 2 1 0 2 2 2 0 MerR, DNA binding NPV_P10 PF05531.7 KFY03493.1 - 0.99 9.7 4.9 1.5 9.0 0.4 3.1 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein BLOC1_2 PF10046.4 KFY03493.1 - 1 9.5 8.2 0.32 11.1 2.4 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF16 PF01519.11 KFY03493.1 - 1.1 9.4 7.2 16 5.7 5.0 2.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF3552 PF12072.3 KFY03493.1 - 1.4 8.1 16.6 0.066 12.4 3.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) RRF_GI PF12614.3 KFY03493.1 - 1.6 8.5 7.6 0.84 9.4 0.7 2.6 1 1 1 2 2 2 0 Ribosome recycling factor Osmo_CC PF08946.5 KFY03493.1 - 2.2 8.3 7.7 8.9 6.4 0.9 3.5 2 1 1 3 3 3 0 Osmosensory transporter coiled coil Spc7 PF08317.6 KFY03493.1 - 3.2 6.3 14.4 1.1 7.8 3.7 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Mod_r PF07200.8 KFY03493.1 - 3.6 7.4 14.9 1.8 8.4 3.7 2.7 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Laminin_II PF06009.7 KFY03493.1 - 5.4 6.7 10.5 1.6 8.4 1.9 2.7 2 2 1 3 3 3 0 Laminin Domain II Prefoldin_2 PF01920.15 KFY03493.1 - 5.4 6.8 15.6 14 5.4 1.6 3.5 2 1 1 3 3 3 0 Prefoldin subunit V_ATPase_I PF01496.14 KFY03493.1 - 8.3 4.1 7.4 2.7 5.7 3.0 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Ribosomal_L37e PF01907.14 KFY03494.1 - 9.3e-27 92.5 10.2 1.4e-26 91.9 7.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 KFY03494.1 - 0.0027 17.4 0.4 0.0039 16.9 0.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 KFY03494.1 - 0.0077 15.4 0.5 0.013 14.7 0.4 1.4 1 0 0 1 1 1 1 zinc-ribbon domain HypA PF01155.14 KFY03494.1 - 0.064 12.9 0.4 0.09 12.4 0.3 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_6 PF14599.1 KFY03494.1 - 0.17 11.6 1.5 0.27 11.0 1.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon zinc_ribbon_2 PF13240.1 KFY03494.1 - 0.5 9.9 3.3 2.8 7.5 2.2 2.1 1 1 1 2 2 2 0 zinc-ribbon domain CENP-O PF09496.5 KFY03495.1 - 2.7e-22 78.7 0.0 6.4e-22 77.5 0.0 1.7 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component DUF2348 PF09807.4 KFY03495.1 - 2.1e-14 53.2 0.0 3.8e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) KaiC PF06745.8 KFY03495.1 - 0.013 14.6 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 KaiC RRM_1 PF00076.17 KFY03496.1 - 2.3e-81 267.4 4.5 7.2e-22 76.8 0.1 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY03496.1 - 1.3e-53 178.8 0.4 3.2e-16 59.0 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFY03496.1 - 5.5e-37 125.4 0.1 1.3e-07 31.3 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KFY03496.1 - 1.1e-28 98.6 0.6 1.1e-28 98.6 0.4 3.1 4 0 0 4 4 4 1 Poly-adenylate binding protein, unique domain Limkain-b1 PF11608.3 KFY03496.1 - 4.3e-06 26.3 3.0 0.22 11.2 0.1 3.9 2 1 1 3 3 3 2 Limkain b1 CbiG_mid PF11761.3 KFY03496.1 - 3.4e-05 24.0 6.0 1.2 9.4 0.0 4.8 5 0 0 5 5 4 2 Cobalamin biosynthesis central region OB_RNB PF08206.6 KFY03496.1 - 0.011 15.2 1.2 5 6.7 0.0 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain Nup35_RRM_2 PF14605.1 KFY03496.1 - 0.013 15.2 0.1 40 4.0 0.0 3.7 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RR_TM4-6 PF06459.7 KFY03496.1 - 0.44 10.3 21.5 0.92 9.3 14.9 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 KFY03496.1 - 0.5 8.3 12.0 0.77 7.7 8.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Med8 PF10232.4 KFY03496.1 - 0.52 9.7 8.2 1.2 8.6 5.7 1.6 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Phyto_Pns9_10 PF05878.6 KFY03496.1 - 1.2 8.0 8.1 2.7 6.9 5.6 1.6 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 RNA_polI_A34 PF08208.6 KFY03496.1 - 1.3 8.6 26.7 2.5 7.7 18.5 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.7 KFY03496.1 - 2.2 8.2 11.5 3.5 7.5 8.0 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family Zip PF02535.17 KFY03496.1 - 3.7 6.4 4.7 6.9 5.5 3.2 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Vfa1 PF08432.5 KFY03496.1 - 3.8 7.4 24.7 0.098 12.6 12.2 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Ycf1 PF05758.7 KFY03496.1 - 3.9 5.0 14.1 5.7 4.5 9.8 1.2 1 0 0 1 1 1 0 Ycf1 DDHD PF02862.12 KFY03496.1 - 7.3 6.3 11.5 15 5.2 8.0 1.5 1 0 0 1 1 1 0 DDHD domain HECT PF00632.20 KFY03497.1 - 1.9e-84 283.5 0.0 3.3e-84 282.7 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 KFY03497.1 - 0.0074 15.8 0.1 0.025 14.1 0.1 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif MRP-L27 PF09809.4 KFY03498.1 - 8.7e-19 67.2 0.2 1.1e-18 66.8 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Utp14 PF04615.8 KFY03499.1 - 1.2e-199 665.1 56.6 1.2e-199 665.1 39.3 2.1 1 1 1 2 2 2 1 Utp14 protein Peptidase_C2 PF00648.16 KFY03500.1 - 2.4e-54 184.3 6.8 5.1e-27 94.6 0.1 3.2 2 1 1 3 3 3 3 Calpain family cysteine protease Trypan_PARP PF05887.6 KFY03500.1 - 7.5 6.3 13.7 0.53 10.1 5.8 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Bgal_small_N PF02929.12 KFY03520.1 - 2.8e-34 118.4 0.1 3.6e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Beta galactosidase small chain ILVD_EDD PF00920.16 KFY03521.1 - 3.4e-198 659.3 3.3 3.9e-198 659.1 2.3 1.0 1 0 0 1 1 1 1 Dehydratase family Kinetochor_Ybp2 PF08568.5 KFY03522.1 - 1.2e-124 416.9 0.0 1.5e-124 416.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin SH3_3 PF08239.6 KFY03523.1 - 0.11 12.6 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain Metallothio_6 PF05522.6 KFY03523.1 - 6 7.2 9.0 0.92 9.8 2.5 2.0 2 0 0 2 2 2 0 Metallothionein Methyltransf_24 PF13578.1 KFY03524.1 - 8.4e-05 23.3 0.0 0.00023 21.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain DUF791 PF05631.9 KFY03525.1 - 6.8e-75 251.9 13.6 9.4e-75 251.5 9.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 KFY03525.1 - 6e-22 77.8 28.1 1.1e-20 73.6 21.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY03525.1 - 1.3e-09 37.1 5.2 1.3e-09 37.1 3.6 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 KFY03525.1 - 0.11 12.2 0.0 0.11 12.2 0.0 2.6 2 2 0 2 2 2 0 MFS_1 like family BAR PF03114.13 KFY03526.1 - 7.7e-61 205.5 3.5 9.5e-61 205.2 2.4 1.1 1 0 0 1 1 1 1 BAR domain SCHIP-1 PF10148.4 KFY03526.1 - 0.08 12.3 0.6 4.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Schwannomin-interacting protein 1 BBE PF08031.7 KFY03532.1 - 0.00073 19.4 1.0 0.0025 17.6 0.7 1.9 2 0 0 2 2 2 1 Berberine and berberine like FAD_binding_4 PF01565.18 KFY03532.1 - 0.026 13.9 0.0 0.056 12.9 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain NmrA PF05368.8 KFY03533.1 - 1.9e-14 53.5 0.0 1.1e-13 50.9 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFY03533.1 - 1.7e-11 44.4 0.0 2.6e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFY03533.1 - 0.024 14.0 0.1 0.12 11.7 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family His_Phos_1 PF00300.17 KFY03535.1 - 3.8e-16 59.5 0.0 5.6e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RAP1 PF07218.6 KFY03535.1 - 1 7.3 7.8 1.6 6.6 5.4 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Gelsolin PF00626.17 KFY03536.1 - 1.6e-36 123.8 0.0 2e-12 46.5 0.0 3.4 3 0 0 3 3 3 3 Gelsolin repeat Hemerythrin PF01814.18 KFY03536.1 - 8.3e-05 22.7 0.0 0.00016 21.8 0.0 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain MFS_1 PF07690.11 KFY03537.1 - 2.8e-43 147.9 64.4 2.6e-36 125.0 16.9 2.5 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFY03537.1 - 1.5e-15 56.4 13.9 2.1e-15 55.9 9.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KFY03537.1 - 3.8e-14 52.1 15.5 3.8e-14 52.1 10.7 3.2 1 1 2 3 3 3 2 Sugar (and other) transporter Trypan_PARP PF05887.6 KFY03537.1 - 0.29 10.9 3.8 0.51 10.1 2.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DJ-1_PfpI PF01965.19 KFY03538.1 - 1.6e-20 73.0 0.1 2.4e-20 72.4 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KFY03538.1 - 5.1e-06 25.9 0.4 1.3e-05 24.5 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of DJ-1_PfpI family Mito_carr PF00153.22 KFY03539.1 - 6e-48 160.5 5.6 9.8e-19 66.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Voltage_CLC PF00654.15 KFY03540.1 - 1.1e-86 291.1 37.9 1.1e-86 291.1 26.2 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KFY03540.1 - 1.7e-08 34.0 0.0 0.0002 21.0 0.1 2.5 2 0 0 2 2 2 2 CBS domain Neurochondrin PF05536.6 KFY03541.1 - 1.4e-76 258.0 0.0 1.7e-76 257.6 0.0 1.1 1 0 0 1 1 1 1 Neurochondrin MARVEL PF01284.18 KFY03542.1 - 8.1e-07 28.9 3.0 8.1e-07 28.9 2.1 2.1 2 0 0 2 2 2 1 Membrane-associating domain Ion_trans PF00520.26 KFY03542.1 - 0.062 12.5 1.9 0.082 12.1 1.3 1.3 1 0 0 1 1 1 0 Ion transport protein RDD PF06271.7 KFY03542.1 - 4.4 7.2 7.5 2.7 7.8 2.7 2.3 2 1 0 2 2 2 0 RDD family Epimerase PF01370.16 KFY03543.1 - 1e-07 31.6 0.0 1.5e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFY03543.1 - 0.00025 21.1 0.0 0.0004 20.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFY03543.1 - 0.0011 17.7 0.0 0.0016 17.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KFY03543.1 - 0.0078 15.1 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 KFY03543.1 - 0.026 14.8 0.0 0.054 13.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 KFY03543.1 - 0.054 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 short chain dehydrogenase POTRA_1 PF08478.5 KFY03543.1 - 0.078 13.0 0.1 0.44 10.6 0.0 2.3 2 0 0 2 2 2 0 POTRA domain, FtsQ-type NmrA PF05368.8 KFY03543.1 - 0.085 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family CFEM PF05730.6 KFY03545.1 - 9e-06 25.4 4.3 1.3e-05 24.9 3.0 1.2 1 0 0 1 1 1 1 CFEM domain NAD_binding_1 PF00175.16 KFY03546.1 - 9.2e-26 90.5 0.0 1.5e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KFY03546.1 - 2.3e-24 85.4 0.0 4.7e-24 84.4 0.0 1.5 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KFY03546.1 - 0.00041 20.2 0.0 0.019 14.8 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ribosomal_L12 PF00542.14 KFY03547.1 - 8.6e-18 64.1 3.1 6.2e-17 61.3 1.1 2.3 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain PP2C_C PF07830.8 KFY03547.1 - 0.037 14.1 0.8 6 7.0 0.0 2.6 2 1 1 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain EIIBC-GUT_N PF03612.9 KFY03547.1 - 0.13 11.8 0.0 2.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus AAA_5 PF07728.9 KFY03548.1 - 3.9e-125 412.1 0.1 5.8e-21 74.6 0.0 9.6 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KFY03548.1 - 3.1e-29 102.2 0.0 0.00012 22.8 0.0 8.0 6 0 0 6 6 6 5 AAA domain AAA_33 PF13671.1 KFY03548.1 - 3e-28 98.4 0.0 0.0011 18.8 0.0 7.5 6 1 0 6 6 6 6 AAA domain AAA_3 PF07726.6 KFY03548.1 - 6.4e-28 96.9 0.0 7.7e-11 41.7 0.0 7.7 8 0 0 8 8 8 2 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KFY03548.1 - 2e-27 96.0 0.0 0.00037 20.6 0.0 7.4 7 0 0 7 7 6 6 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFY03548.1 - 3.4e-26 92.3 15.4 0.00014 21.8 0.1 8.8 8 0 0 8 8 6 5 AAA ATPase domain AAA_22 PF13401.1 KFY03548.1 - 8.7e-25 87.3 1.7 0.0065 16.6 0.0 8.7 8 1 0 8 8 7 6 AAA domain AAA_14 PF13173.1 KFY03548.1 - 6.2e-21 74.6 0.0 0.0014 18.5 0.0 7.7 7 0 0 7 7 6 3 AAA domain Sigma54_activ_2 PF14532.1 KFY03548.1 - 1.3e-19 70.6 0.4 0.00066 19.7 0.0 7.8 7 0 0 7 7 7 3 Sigma-54 interaction domain AAA_18 PF13238.1 KFY03548.1 - 1.4e-19 70.6 0.4 0.005 17.1 0.0 7.3 6 0 0 6 6 6 3 AAA domain Sigma54_activat PF00158.21 KFY03548.1 - 1.7e-19 69.8 0.5 0.027 13.9 0.0 6.6 6 0 0 6 6 6 5 Sigma-54 interaction domain ABC_tran PF00005.22 KFY03548.1 - 1.8e-17 63.9 3.6 0.0061 16.8 0.0 7.5 7 0 0 7 7 6 4 ABC transporter DUF258 PF03193.11 KFY03548.1 - 1.5e-16 59.9 1.1 0.017 14.3 0.0 6.1 6 0 0 6 6 6 4 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KFY03548.1 - 4.3e-15 55.8 5.1 0.097 12.8 0.0 7.6 7 0 0 7 7 7 3 RNA helicase UPF0079 PF02367.12 KFY03548.1 - 2.1e-14 53.1 4.0 0.1 12.2 0.0 6.4 6 0 0 6 6 6 4 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KFY03548.1 - 2.8e-14 53.1 5.2 0.16 11.6 0.0 6.2 5 0 0 5 5 5 4 NACHT domain MobB PF03205.9 KFY03548.1 - 2.4e-13 49.9 0.7 0.9 9.2 0.0 6.7 6 0 0 6 6 6 3 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 KFY03548.1 - 2.8e-13 49.4 5.2 0.0052 16.5 0.1 6.7 6 0 0 6 6 6 3 Part of AAA domain T2SE PF00437.15 KFY03548.1 - 3.8e-13 48.9 1.4 0.06 12.2 0.0 6.4 6 0 0 6 6 6 3 Type II/IV secretion system protein Zeta_toxin PF06414.7 KFY03548.1 - 5.3e-13 48.5 5.1 0.58 9.2 0.0 7.3 7 0 0 7 7 7 3 Zeta toxin Arch_ATPase PF01637.13 KFY03548.1 - 1.1e-12 48.1 0.0 0.035 13.7 0.0 6.8 6 0 0 6 6 6 1 Archaeal ATPase AAA_29 PF13555.1 KFY03548.1 - 1.9e-12 46.4 0.2 0.13 11.7 0.0 6.5 6 0 0 6 6 6 2 P-loop containing region of AAA domain Miro PF08477.8 KFY03548.1 - 4.6e-12 46.4 2.7 3.5 8.1 0.0 6.9 6 0 0 6 6 6 0 Miro-like protein AAA_25 PF13481.1 KFY03548.1 - 5.8e-12 45.4 0.5 0.57 9.5 0.0 6.0 5 0 0 5 5 5 4 AAA domain AAA_28 PF13521.1 KFY03548.1 - 1.1e-11 44.9 4.2 0.11 12.4 0.0 7.5 7 0 0 7 7 6 1 AAA domain IstB_IS21 PF01695.12 KFY03548.1 - 8.6e-10 38.3 0.3 0.28 10.5 0.0 5.7 6 0 0 6 6 6 2 IstB-like ATP binding protein RuvB_N PF05496.7 KFY03548.1 - 6.4e-09 35.1 4.5 0.037 13.0 0.0 6.5 7 0 0 7 7 7 2 Holliday junction DNA helicase ruvB N-terminus PduV-EutP PF10662.4 KFY03548.1 - 1.5e-08 34.2 3.5 0.022 14.2 0.0 5.8 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 KFY03548.1 - 1.9e-08 33.9 4.2 0.69 9.3 0.0 5.6 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.18 KFY03548.1 - 2.9e-08 33.6 0.5 4.6 7.2 0.0 6.7 6 0 0 6 6 6 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.13 KFY03548.1 - 1.1e-07 31.5 0.1 1.1 8.7 0.0 6.1 6 0 0 6 6 6 1 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 KFY03548.1 - 2.8e-07 29.6 0.4 0.97 8.0 0.0 5.5 6 0 0 6 6 6 2 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 KFY03548.1 - 7.5e-07 28.9 0.0 3.9 6.9 0.0 6.0 6 0 0 6 6 6 0 AAA domain FtsK_SpoIIIE PF01580.13 KFY03548.1 - 1.5e-06 27.8 3.3 3.8 6.9 0.0 5.6 5 0 0 5 5 5 0 FtsK/SpoIIIE family cobW PF02492.14 KFY03548.1 - 3e-06 26.7 3.2 4.8 6.5 0.0 5.8 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 KFY03548.1 - 3.6e-06 26.7 7.0 0.97 9.1 0.1 5.9 6 0 0 6 6 5 2 NTPase Thymidylate_kin PF02223.12 KFY03548.1 - 5.7e-06 25.8 0.3 4.8 6.5 0.0 5.8 5 0 0 5 5 5 0 Thymidylate kinase AAA_7 PF12775.2 KFY03548.1 - 3.9e-05 22.8 1.7 0.84 8.6 0.0 4.7 5 0 0 5 5 4 1 P-loop containing dynein motor region D3 TIP49 PF06068.8 KFY03548.1 - 0.00016 20.5 4.0 0.54 8.9 0.0 4.8 6 0 0 6 6 5 1 TIP49 C-terminus ATP-synt_ab PF00006.20 KFY03548.1 - 0.00088 18.8 0.1 17 4.8 0.0 4.9 5 0 0 5 5 5 0 ATP synthase alpha/beta family, nucleotide-binding domain KaiC PF06745.8 KFY03548.1 - 0.0011 18.1 0.2 14 4.7 0.0 4.5 4 0 0 4 4 4 0 KaiC AAA_6 PF12774.2 KFY03548.1 - 0.0011 18.6 0.1 4.3 6.7 0.0 5.9 8 1 0 8 8 7 0 Hydrolytic ATP binding site of dynein motor region D1 PRK PF00485.13 KFY03548.1 - 0.0013 18.3 1.3 2.6 7.5 0.0 5.2 6 0 0 6 6 5 1 Phosphoribulokinase / Uridine kinase family PhoH PF02562.11 KFY03548.1 - 0.0037 16.5 2.9 6 6.0 0.0 5.0 5 1 0 5 5 5 0 PhoH-like protein ATP_bind_1 PF03029.12 KFY03548.1 - 0.0071 15.9 7.3 7 6.1 0.1 5.6 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein VirE PF05272.6 KFY03548.1 - 0.0077 15.7 0.1 2.1 7.7 0.0 4.1 6 0 0 6 6 5 1 Virulence-associated protein E NB-ARC PF00931.17 KFY03548.1 - 0.019 13.8 6.2 15 4.3 0.1 5.2 6 0 0 6 6 6 0 NB-ARC domain Ras PF00071.17 KFY03548.1 - 0.045 13.1 1.9 31 3.8 0.0 4.6 5 0 0 5 5 5 0 Ras family tRNA_lig_kinase PF08303.6 KFY03548.1 - 0.055 13.3 0.1 0.32 10.8 0.0 2.4 2 0 0 2 2 1 0 tRNA ligase kinase domain CbiA PF01656.18 KFY03548.1 - 0.12 11.8 4.5 9.5 5.5 0.1 4.2 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain Dynamin_N PF00350.18 KFY03548.1 - 0.15 11.8 3.4 7.3 6.3 0.0 4.6 4 0 0 4 4 4 0 Dynamin family ArgK PF03308.11 KFY03548.1 - 0.55 8.9 4.9 15 4.2 0.0 3.6 5 0 0 5 5 3 0 ArgK protein AAA_23 PF13476.1 KFY03548.1 - 2.4 8.4 0.0 2.4 8.4 0.0 9.4 9 2 0 9 9 7 0 AAA domain Sugar_tr PF00083.19 KFY03549.1 - 6.2e-82 275.5 22.5 7.8e-82 275.2 15.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY03549.1 - 1.7e-30 105.9 26.4 1.7e-30 105.9 18.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFY03549.1 - 0.00019 19.7 3.7 0.0003 19.1 2.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KFY03549.1 - 0.042 11.9 2.6 0.067 11.2 1.8 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector Glyco_hydro_43 PF04616.9 KFY03550.1 - 1.8e-55 188.0 3.6 2.4e-55 187.6 2.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF4178 PF13785.1 KFY03550.1 - 0.084 12.8 0.7 0.39 10.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4178) FCH PF00611.18 KFY03563.1 - 1.3e-15 57.3 0.0 1.4e-15 57.2 0.0 1.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Not1 PF04054.10 KFY03564.1 - 4.1e-130 434.0 0.0 8.1e-130 433.0 0.0 1.5 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 KFY03564.1 - 1.3e-43 148.2 5.8 4e-43 146.6 4.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Avirulence PF03377.8 KFY03564.1 - 0.022 13.4 0.1 0.04 12.6 0.0 1.3 1 0 0 1 1 1 0 Xanthomonas avirulence protein, Avr/PthA NTF2 PF02136.15 KFY03566.1 - 9.1e-29 100.2 0.0 1.4e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Cg6151-P PF10233.4 KFY03567.1 - 1.3e-40 137.9 13.3 1.5e-40 137.6 9.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P CbiQ PF02361.11 KFY03567.1 - 0.88 9.0 10.5 1.2 8.7 7.3 1.1 1 0 0 1 1 1 0 Cobalt transport protein DUF3566 PF12089.3 KFY03567.1 - 1.1 9.3 6.1 2.2 8.3 4.2 1.6 1 1 0 1 1 1 0 Transmembrane domain of unknown function (DUF3566) Ion_trans PF00520.26 KFY03571.1 - 1.1e-93 312.0 90.7 8.3e-31 106.7 7.8 6.2 6 1 0 6 6 6 4 Ion transport protein EF-hand_1 PF00036.27 KFY03571.1 - 4e-05 22.6 0.0 0.00012 21.1 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 KFY03571.1 - 0.0008 19.0 0.0 0.0032 17.2 0.0 2.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 KFY03571.1 - 0.004 17.2 0.0 0.011 15.8 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair PKD_channel PF08016.7 KFY03571.1 - 8.1 4.7 61.4 0.0052 15.2 5.8 6.6 6 1 1 7 7 7 0 Polycystin cation channel ADH_zinc_N_2 PF13602.1 KFY03573.1 - 6.3e-21 75.5 0.0 1.2e-20 74.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KFY03573.1 - 1.4e-12 47.3 0.0 2.4e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2173 PF09941.4 KFY03573.1 - 0.036 13.9 0.1 0.065 13.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2173) Cupin_2 PF07883.6 KFY03574.1 - 1e-09 37.7 0.0 1.7e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain CDO_I PF05995.7 KFY03574.1 - 0.0012 18.0 0.0 0.0024 17.0 0.0 1.5 1 1 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 KFY03574.1 - 0.043 13.1 0.0 0.053 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1637) AAA_33 PF13671.1 KFY03575.1 - 5.5e-15 55.4 0.0 7.1e-13 48.6 0.0 2.6 1 1 0 1 1 1 1 AAA domain RNA_ligase PF09414.5 KFY03575.1 - 1.2e-09 38.2 0.0 1.8e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 RNA ligase AAA_22 PF13401.1 KFY03575.1 - 0.00088 19.4 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFY03575.1 - 0.0054 17.5 0.0 0.024 15.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KFY03575.1 - 0.022 14.7 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KFY03575.1 - 0.023 14.8 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) EF-hand_7 PF13499.1 KFY03575.1 - 0.031 14.4 0.0 0.09 12.9 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair RNA_lig_T4_1 PF09511.5 KFY03575.1 - 0.063 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA ligase DUF1325 PF07039.6 KFY03581.1 - 3.3e-27 94.6 0.0 4.1e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF3232 PF11554.3 KFY03581.1 - 0.004 17.0 0.1 0.0061 16.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3232) DUF4537 PF15057.1 KFY03581.1 - 0.084 12.6 0.2 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) Ran_BP1 PF00638.13 KFY03582.1 - 0.093 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 RanBP1 domain NUP50 PF08911.6 KFY03582.1 - 0.13 12.6 0.1 0.13 12.6 0.0 8.5 7 1 0 7 7 7 0 NUP50 (Nucleoporin 50 kDa) Glyco_tranf_2_4 PF13704.1 KFY03587.1 - 9.3e-09 35.4 1.4 1.9e-08 34.5 1.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.22 KFY03587.1 - 1.1e-07 31.4 0.4 2.8e-07 30.1 0.3 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 92 RRF PF01765.14 KFY03594.1 - 7.6e-32 110.0 0.4 1e-31 109.6 0.3 1.1 1 0 0 1 1 1 1 Ribosome recycling factor HSP70 PF00012.15 KFY03594.1 - 1.9e-13 49.2 0.1 3e-13 48.5 0.1 1.4 1 1 0 1 1 1 1 Hsp70 protein HSP70 PF00012.15 KFY03595.1 - 1.5e-20 72.7 6.7 1.6e-20 72.6 4.7 1.0 1 0 0 1 1 1 1 Hsp70 protein ATP-synt_DE PF00401.15 KFY03595.1 - 0.042 13.7 3.2 0.49 10.3 0.2 2.4 1 1 1 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain DUF406 PF04175.7 KFY03595.1 - 0.056 13.9 0.5 0.11 13.0 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF406) BACON PF13004.2 KFY03595.1 - 0.062 13.5 0.3 0.1 12.8 0.2 1.4 1 0 0 1 1 1 0 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal RNA_polI_A14 PF08203.6 KFY03595.1 - 0.19 12.0 1.9 0.37 11.0 0.6 1.9 1 1 1 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Scaffolding_pro PF11418.3 KFY03595.1 - 2.3 8.6 6.3 2.9 8.2 3.2 1.8 1 1 0 2 2 2 0 Phi29 scaffolding protein zf-C2H2 PF00096.21 KFY03596.1 - 0.06 13.7 0.4 0.06 13.7 0.3 1.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF2841 PF11001.3 KFY03597.1 - 1.1e-35 122.2 0.3 1.6e-35 121.6 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) DUF3613 PF12266.3 KFY03598.1 - 1.5 8.4 17.4 2.4 7.7 4.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3613) Catalase PF00199.14 KFY03599.1 - 6e-162 538.6 0.6 7.6e-162 538.3 0.4 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KFY03599.1 - 1.6e-17 63.1 0.0 4.1e-17 61.7 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 KFY03599.1 - 1.1e-10 41.1 0.1 2.3e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KFY03599.1 - 2.9e-06 26.6 0.0 5.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase Glyco_hydro_28 PF00295.12 KFY03600.1 - 3.4e-93 312.1 22.3 3.9e-93 311.9 15.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 KFY03600.1 - 0.05 13.3 42.1 0.019 14.6 14.6 3.1 1 1 1 2 2 2 0 Right handed beta helix region DUF3414 PF11894.3 KFY03602.1 - 0 1343.9 16.4 0 1343.5 11.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Cullin PF00888.17 KFY03602.1 - 1.2e-123 413.6 4.3 8.7e-123 410.9 2.7 2.1 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 KFY03602.1 - 1.7e-25 88.6 0.7 7.4e-25 86.5 0.5 2.3 1 0 0 1 1 1 1 Cullin protein neddylation domain PI3_PI4_kinase PF00454.22 KFY03603.1 - 8.5e-49 166.1 0.0 1.5e-48 165.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 KFY03603.1 - 2.1e-33 115.2 1.7 6.1e-33 113.7 0.1 2.7 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 KFY03603.1 - 1.1e-11 43.9 0.1 3.8e-11 42.2 0.0 2.0 2 0 0 2 2 2 1 FATC domain UPF0052 PF01933.13 KFY03604.1 - 1.2e-51 175.8 0.0 1.4e-51 175.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 zf-C3HC4_3 PF13920.1 KFY03605.1 - 2.1e-11 43.2 5.6 3.2e-11 42.7 3.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFY03605.1 - 5.7e-10 38.8 8.1 9.3e-10 38.1 5.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFY03605.1 - 1.3e-08 34.3 6.5 2e-08 33.7 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFY03605.1 - 1.5e-08 34.5 7.7 2.3e-08 33.9 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFY03605.1 - 1.3e-07 31.1 7.5 2.1e-07 30.5 5.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 KFY03605.1 - 0.00014 21.3 4.3 0.00024 20.5 3.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 KFY03605.1 - 0.0018 18.0 0.9 0.0032 17.2 0.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 KFY03605.1 - 0.0021 17.8 3.1 0.0036 17.1 2.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KFY03605.1 - 0.0038 17.0 6.8 0.0075 16.1 4.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KFY03605.1 - 0.004 16.8 5.7 0.0056 16.3 2.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger Baculo_IE-1 PF05290.6 KFY03605.1 - 0.05 13.3 0.1 0.07 12.8 0.1 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-rbx1 PF12678.2 KFY03605.1 - 0.23 11.5 5.5 0.59 10.2 3.8 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-UDP PF14569.1 KFY03605.1 - 0.51 10.1 2.7 1.5 8.6 1.9 1.8 1 1 0 1 1 1 0 Zinc-binding RING-finger UPF0547 PF10571.4 KFY03605.1 - 0.63 9.7 4.4 8.6 6.1 0.3 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Prok-RING_4 PF14447.1 KFY03605.1 - 8.7 5.9 8.5 27 4.4 5.9 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Ribosomal_L16 PF00252.13 KFY03606.1 - 1.5e-30 105.6 0.6 2e-30 105.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DNA_pol_A PF00476.15 KFY03607.1 - 3.4e-101 338.6 0.0 5.4e-101 337.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A GFO_IDH_MocA PF01408.17 KFY03608.1 - 4.4e-18 65.9 0.2 8.3e-18 65.0 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KFY03608.1 - 0.00023 20.9 0.0 0.00048 19.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 KFY03608.1 - 0.013 15.8 0.1 0.031 14.5 0.1 1.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Adap_comp_sub PF00928.16 KFY03609.1 - 2.5e-85 285.7 0.0 3.4e-85 285.3 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family PLAC8 PF04749.12 KFY03609.1 - 8.9e-17 61.5 13.6 1.6e-16 60.7 9.4 1.4 1 0 0 1 1 1 1 PLAC8 family Clat_adaptor_s PF01217.15 KFY03609.1 - 2.4e-05 24.0 0.2 4.6e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1081 PF06448.6 KFY03609.1 - 0.058 13.2 0.2 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) CorA PF01544.13 KFY03610.1 - 9.7e-14 51.0 0.1 1.3e-13 50.6 0.1 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein peroxidase PF00141.18 KFY03613.1 - 7.7e-49 166.2 0.0 1e-48 165.8 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Lipase_3 PF01764.20 KFY03614.1 - 6.6e-09 35.5 0.0 1.1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) 7kD_coat PF02495.12 KFY03614.1 - 0.077 12.4 0.0 0.24 10.8 0.0 1.8 2 0 0 2 2 2 0 7kD viral coat protein Abhydrolase_6 PF12697.2 KFY03614.1 - 0.12 12.2 0.2 0.2 11.4 0.2 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_76 PF03663.9 KFY03615.1 - 2.5e-34 119.2 0.1 2.8e-34 119.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 VMA21 PF09446.5 KFY03615.1 - 0.0032 17.3 0.2 0.0061 16.4 0.1 1.5 1 0 0 1 1 1 1 VMA21-like domain Sugar_tr PF00083.19 KFY03617.1 - 7.8e-117 390.6 24.2 1.2e-116 389.9 16.8 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY03617.1 - 1.5e-30 106.0 48.8 2.3e-25 89.0 15.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Lysis_S PF04971.7 KFY03617.1 - 0.0014 18.2 0.4 0.0071 15.9 0.3 2.2 1 0 0 1 1 1 1 Lysis protein S peroxidase PF00141.18 KFY03618.1 - 4.4e-86 288.0 0.0 1.6e-50 171.7 0.0 2.2 2 0 0 2 2 2 2 Peroxidase Herpes_U59 PF04529.7 KFY03618.1 - 0.081 11.7 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus U59 protein CN_hydrolase PF00795.17 KFY03619.1 - 9e-25 87.1 0.0 1.3e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CFEM PF05730.6 KFY03620.1 - 1.9e-08 34.0 10.3 1.9e-08 34.0 7.1 2.0 2 0 0 2 2 2 1 CFEM domain Zn_clus PF00172.13 KFY03620.1 - 0.00032 20.5 11.2 0.00064 19.5 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KFY03621.1 - 1.4e-41 142.4 58.9 8.3e-41 139.8 40.5 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KFY03621.1 - 2e-13 49.4 20.0 3e-13 48.8 13.6 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 KFY03621.1 - 0.009 15.7 4.2 0.009 15.7 2.9 2.1 2 0 0 2 2 2 1 MFS_1 like family Ribosomal_L11_N PF03946.9 KFY03622.1 - 0.071 12.5 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain Pkinase PF00069.20 KFY03623.1 - 4e-31 108.1 0.0 8.1e-31 107.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY03623.1 - 6.3e-10 38.5 0.0 0.00055 19.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.17 KFY03623.1 - 0.00036 19.9 0.0 0.00059 19.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Sod_Cu PF00080.15 KFY03624.1 - 1.4e-44 151.7 5.1 1.6e-44 151.4 3.6 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Tox-HNH-EHHH PF15657.1 KFY03624.1 - 0.37 10.9 4.1 0.088 12.9 0.7 1.7 2 0 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxins Xan_ur_permease PF00860.15 KFY03626.1 - 1e-21 76.9 32.3 5.1e-21 74.5 22.4 2.2 1 1 0 1 1 1 1 Permease family QRPTase_N PF02749.11 KFY03627.1 - 6.5e-10 38.7 0.0 9.2e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Mito_carr PF00153.22 KFY03630.1 - 8.9e-15 54.1 1.0 0.015 14.9 0.0 5.2 4 1 0 4 4 4 4 Mitochondrial carrier protein Nop10p PF04135.7 KFY03631.1 - 8.1e-19 67.1 0.1 2.1e-18 65.7 0.1 1.8 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family TPR_10 PF13374.1 KFY03632.1 - 4.7e-32 108.9 0.0 3.3e-13 49.0 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KFY03632.1 - 3.6e-28 97.3 0.0 4.1e-13 49.0 0.0 2.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFY03632.1 - 1.1e-06 27.9 0.1 0.0016 18.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFY03632.1 - 1.3e-05 25.0 0.1 0.041 14.1 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KFY03632.1 - 0.00029 20.5 0.0 0.36 10.8 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KFY03632.1 - 0.0017 17.9 0.0 0.0096 15.5 0.0 2.0 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KFY03632.1 - 0.0041 16.6 0.0 0.18 11.4 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_5 PF12688.2 KFY03632.1 - 0.018 15.0 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Tetratrico peptide repeat TPR_14 PF13428.1 KFY03632.1 - 0.059 14.0 0.1 1.9 9.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KFY03632.1 - 0.096 13.1 0.1 2.1 9.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KFY03632.1 - 0.16 11.8 0.0 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.2 KFY03637.1 - 2.2e-54 181.7 0.2 1.6e-14 53.9 0.0 5.2 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 KFY03637.1 - 4.4e-40 133.5 11.7 7.1e-05 22.4 0.0 10.1 10 0 0 10 10 10 8 Ankyrin repeat Ank_5 PF13857.1 KFY03637.1 - 8.3e-38 127.5 2.8 8.4e-07 29.0 0.0 7.4 3 1 4 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY03637.1 - 2.2e-34 114.0 3.9 0.001 19.0 0.0 10.0 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.1 KFY03637.1 - 9.4e-31 105.6 1.3 2.5e-08 34.1 0.0 6.6 2 1 4 7 7 7 7 Ankyrin repeats (many copies) TRI12 PF06609.8 KFY03644.1 - 7.7e-98 328.2 24.8 9.7e-98 327.8 17.2 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KFY03644.1 - 3.5e-19 68.7 48.0 3.5e-19 68.7 33.3 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY03644.1 - 9.7e-08 31.0 16.2 9.7e-08 31.0 11.3 3.4 2 2 1 3 3 3 1 Sugar (and other) transporter DUF3040 PF11239.3 KFY03644.1 - 0.062 13.3 0.2 0.062 13.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) DUF4097 PF13349.1 KFY03644.1 - 2.4 7.6 6.0 0.15 11.5 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4097) Pyr_redox_3 PF13738.1 KFY03645.1 - 7.2e-22 78.4 0.0 3.4e-20 72.9 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KFY03645.1 - 1.2e-07 31.9 0.0 0.00031 20.8 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.14 KFY03645.1 - 4.1e-07 28.5 0.0 1.5e-05 23.4 0.0 2.2 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KFY03645.1 - 2.9e-06 27.1 0.1 1.7e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KFY03645.1 - 1.7e-05 23.8 0.0 0.092 11.6 0.0 3.6 3 1 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KFY03645.1 - 0.00019 21.2 0.3 0.14 11.9 0.1 3.7 4 0 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.19 KFY03645.1 - 0.0014 17.6 2.4 0.75 8.6 0.2 2.9 2 1 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KFY03645.1 - 0.0025 16.7 0.0 0.03 13.2 0.0 2.3 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 KFY03645.1 - 0.021 15.0 0.1 2.7 8.3 0.0 2.7 3 0 0 3 3 3 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 KFY03645.1 - 0.038 12.8 0.0 0.075 11.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain ThiF PF00899.16 KFY03645.1 - 0.11 12.3 2.8 0.17 11.7 0.3 2.4 3 0 0 3 3 3 0 ThiF family NAD_binding_2 PF03446.10 KFY03645.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_N PF08240.7 KFY03646.1 - 5.1e-21 74.4 3.4 1e-18 67.1 2.3 2.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFY03646.1 - 1.6e-17 63.2 1.2 3.6e-17 62.1 0.8 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFY03646.1 - 6e-12 46.5 0.4 1.4e-11 45.3 0.1 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Qn_am_d_aII PF14930.1 KFY03646.1 - 0.021 14.7 0.0 0.053 13.4 0.0 1.7 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II NAD_binding_2 PF03446.10 KFY03646.1 - 0.03 14.1 0.3 0.061 13.1 0.2 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GST_C_3 PF14497.1 KFY03648.1 - 3.5e-11 43.4 0.0 5.3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KFY03648.1 - 4.1e-06 26.5 0.2 9.8e-05 22.1 0.1 2.5 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KFY03648.1 - 0.0021 18.2 0.1 0.041 14.1 0.1 2.7 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain F-box-like PF12937.2 KFY03649.1 - 0.0041 16.7 0.0 0.014 15.0 0.0 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KFY03649.1 - 0.068 12.8 0.2 9.7 5.9 0.0 2.9 3 0 0 3 3 3 0 F-box domain Acetyltransf_7 PF13508.1 KFY03651.1 - 2.9e-06 27.3 0.0 4.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFY03651.1 - 6.5e-06 26.2 0.0 1.2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFY03651.1 - 2.2e-05 24.3 0.1 0.0021 17.8 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFY03651.1 - 0.00015 21.7 0.0 0.00025 20.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 KFY03651.1 - 0.046 13.6 0.0 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase MOZ_SAS PF01853.13 KFY03651.1 - 0.063 12.5 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family FR47 PF08445.5 KFY03651.1 - 0.13 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein TRAM_LAG1_CLN8 PF03798.11 KFY03653.1 - 1.9e-33 115.7 12.3 1.9e-33 115.7 8.5 1.5 2 0 0 2 2 2 1 TLC domain USP7_ICP0_bdg PF12436.3 KFY03654.1 - 9.4e-42 142.9 0.1 1.5e-41 142.2 0.1 1.3 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.24 KFY03654.1 - 9.2e-40 136.4 0.0 1.5e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFY03654.1 - 9.9e-20 71.1 0.0 1.5e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KFY03654.1 - 7e-12 45.6 0.1 1.9e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 MATH domain UN_NPL4 PF11543.3 KFY03654.1 - 0.094 13.0 0.0 2.5 8.4 0.0 2.6 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 RPE65 PF03055.10 KFY03655.1 - 5e-89 299.1 0.1 7.3e-89 298.5 0.1 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Zn_clus PF00172.13 KFY03656.1 - 5.7e-07 29.3 10.9 5.7e-07 29.3 7.6 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFY03656.1 - 1.4e-06 27.1 0.4 2.4e-06 26.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cu-oxidase PF00394.17 KFY03657.1 - 2.1e-32 112.2 0.0 1.3e-31 109.6 0.0 2.1 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 KFY03657.1 - 8e-32 109.4 0.5 3.2e-31 107.5 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KFY03657.1 - 8.7e-25 86.8 8.1 5.9e-22 77.6 0.7 3.0 2 2 0 2 2 2 2 Multicopper oxidase Acetyltransf_1 PF00583.19 KFY03658.1 - 3.6e-07 30.1 0.0 5.2e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFY03658.1 - 1.8e-06 27.9 0.0 2.7e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFY03658.1 - 2e-05 24.4 0.0 0.00024 20.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFY03658.1 - 5.9e-05 23.1 0.2 0.00032 20.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFY03658.1 - 0.025 14.4 0.1 0.069 13.0 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase FR47 PF08445.5 KFY03658.1 - 0.048 13.4 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein MOZ_SAS PF01853.13 KFY03658.1 - 0.14 11.3 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family Pyr_redox_2 PF07992.9 KFY03659.1 - 3.8e-28 98.7 0.2 5.5e-28 98.2 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFY03659.1 - 7.4e-17 61.5 1.2 1.1e-14 54.5 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFY03659.1 - 9.9e-12 45.3 0.1 2.5e-06 27.7 0.0 3.5 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KFY03659.1 - 1.6e-05 25.0 0.1 0.0032 17.6 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 KFY03659.1 - 4.9e-05 23.2 0.1 0.038 14.0 0.0 3.1 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFY03659.1 - 8.6e-05 21.7 0.0 0.00059 19.0 0.0 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 KFY03659.1 - 0.00033 19.6 1.3 1.5 7.6 0.1 3.3 3 1 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 KFY03659.1 - 0.0044 15.9 0.1 0.18 10.7 0.0 2.9 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 KFY03659.1 - 0.014 14.3 3.7 1.2 7.9 0.1 3.3 3 1 1 4 4 4 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 KFY03659.1 - 0.025 14.6 0.1 3.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 KFY03659.1 - 0.04 12.3 0.5 0.64 8.4 0.1 2.7 3 0 0 3 3 3 0 HI0933-like protein Trp_halogenase PF04820.9 KFY03659.1 - 0.054 12.1 0.1 0.5 8.9 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase FAD_binding_3 PF01494.14 KFY03659.1 - 0.055 12.5 0.5 4.5 6.2 0.0 2.4 2 1 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.19 KFY03659.1 - 0.13 11.0 3.9 0.14 10.9 0.2 2.7 2 1 1 3 3 3 0 FAD binding domain MCPVI PF02993.9 KFY03660.1 - 0.27 11.3 4.6 0.41 10.7 3.2 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Neisseria_TspB PF05616.8 KFY03660.1 - 5.7 5.1 7.9 6.8 4.9 5.5 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Totivirus_coat PF05518.6 KFY03660.1 - 7.9 4.1 11.9 10 3.8 8.3 1.1 1 0 0 1 1 1 0 Totivirus coat protein WD40 PF00400.27 KFY03661.1 - 1.1e-17 63.1 9.3 5.6e-06 26.0 0.1 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Kinesin PF00225.18 KFY03663.1 - 4.2e-57 193.3 0.0 5.7e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain SAM_PNT PF02198.11 KFY03663.1 - 0.059 13.1 0.0 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain AAA_22 PF13401.1 KFY03663.1 - 0.13 12.3 0.2 0.81 9.8 0.1 2.3 3 1 0 3 3 3 0 AAA domain OPT PF03169.10 KFY03664.1 - 2.1e-129 432.8 48.3 2.4e-129 432.6 33.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.3 KFY03664.1 - 0.35 10.6 4.6 1.3 8.8 3.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) Metallophos PF00149.23 KFY03665.1 - 9.4e-20 70.8 1.1 2e-19 69.7 0.8 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 KFY03665.1 - 3.9e-18 65.2 1.0 1.3e-17 63.5 0.7 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 KFY03665.1 - 1.8e-06 26.8 0.0 3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase fn3 PF00041.16 KFY03665.1 - 0.1 12.7 0.7 0.34 11.0 0.3 2.0 2 0 0 2 2 2 0 Fibronectin type III domain HET PF06985.6 KFY03666.1 - 4.5e-26 91.6 0.1 8.6e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peroxidase_2 PF01328.12 KFY03666.1 - 6.5e-18 64.4 0.1 1.1e-17 63.6 0.1 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 F-box PF00646.28 KFY03667.1 - 0.00012 21.5 0.2 0.00051 19.6 0.0 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KFY03667.1 - 0.0023 17.6 0.5 0.0023 17.6 0.3 2.0 2 0 0 2 2 2 1 F-box-like HeLo PF14479.1 KFY03668.1 - 3.6e-10 39.9 0.1 7e-10 39.0 0.1 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.20 KFY03668.1 - 0.00016 20.9 0.0 0.00034 19.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY03668.1 - 0.0022 17.1 0.0 0.0052 15.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase TPR_12 PF13424.1 KFY03670.1 - 1.8e-63 210.4 44.4 9.2e-10 38.3 0.5 12.1 6 3 2 11 11 11 11 Tetratricopeptide repeat Ank_2 PF12796.2 KFY03670.1 - 7.4e-47 157.6 0.0 5.4e-15 55.4 0.0 6.4 4 2 1 6 6 5 5 Ankyrin repeats (3 copies) TPR_10 PF13374.1 KFY03670.1 - 4e-44 147.3 34.1 6.4e-06 25.9 0.0 17.7 19 0 0 19 19 19 10 Tetratricopeptide repeat Ank PF00023.25 KFY03670.1 - 1.6e-35 119.1 18.3 2.5e-05 23.8 0.1 11.4 10 1 1 11 11 11 7 Ankyrin repeat Ank_3 PF13606.1 KFY03670.1 - 1.5e-30 102.2 11.3 0.00077 19.4 0.0 12.0 11 0 0 11 11 11 6 Ankyrin repeat Ank_4 PF13637.1 KFY03670.1 - 3.8e-25 87.7 4.6 8.4e-08 32.5 0.0 8.8 5 2 2 8 8 8 5 Ankyrin repeats (many copies) Pkinase PF00069.20 KFY03670.1 - 6e-22 78.0 0.0 1.3e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.1 KFY03670.1 - 1.8e-21 75.6 2.4 5.4e-06 26.4 0.0 8.7 7 2 1 8 8 8 5 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.12 KFY03670.1 - 1.3e-18 67.0 0.0 2.5e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_16 PF13432.1 KFY03670.1 - 2.6e-10 40.6 17.7 0.0077 16.8 0.2 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 KFY03670.1 - 0.00028 20.4 26.7 0.076 12.8 0.1 9.0 10 0 0 10 10 8 3 Tetratricopeptide repeat Sel1 PF08238.7 KFY03670.1 - 0.00078 20.0 0.6 0.0049 17.4 0.0 2.7 2 0 0 2 2 2 1 Sel1 repeat TPR_2 PF07719.12 KFY03670.1 - 0.00087 19.0 30.4 2.7 8.1 0.0 9.9 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFY03670.1 - 0.4 10.3 26.8 3.2 7.5 0.0 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat Proteasome PF00227.21 KFY03674.1 - 6.2e-10 38.6 0.0 6.8e-10 38.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit E1-E2_ATPase PF00122.15 KFY03675.1 - 6.3e-63 211.8 9.3 1.4e-62 210.7 5.8 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFY03675.1 - 6.3e-46 156.1 10.9 8.9e-46 155.7 5.0 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFY03675.1 - 7.4e-33 114.7 0.0 8.2e-32 111.3 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFY03675.1 - 9.9e-22 76.7 0.0 2e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KFY03675.1 - 3.2e-19 68.1 0.0 9.2e-19 66.6 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFY03675.1 - 1e-17 64.9 0.0 2.6e-17 63.6 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KFY03675.1 - 2.8e-08 33.6 0.5 3.5e-06 26.7 0.4 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KFY03675.1 - 0.022 14.9 0.0 0.097 12.8 0.0 2.1 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Proteasome_A_N PF10584.4 KFY03675.1 - 0.093 12.0 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature 14-3-3 PF00244.15 KFY03677.1 - 7.1e-115 382.0 2.6 7.1e-115 382.0 1.8 1.3 2 0 0 2 2 2 1 14-3-3 protein TPR_12 PF13424.1 KFY03677.1 - 0.0027 17.6 1.8 0.55 10.2 0.3 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF4085 PF13315.1 KFY03677.1 - 0.02 14.2 0.2 0.034 13.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) HisKA PF00512.20 KFY03677.1 - 0.06 13.3 0.2 15 5.6 0.0 3.1 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain MCM_N PF14551.1 KFY03677.1 - 1.1 9.7 3.0 5.7 7.4 0.2 2.3 1 1 1 2 2 2 0 MCM N-terminal domain Acyl-CoA_dh_1 PF00441.19 KFY03680.1 - 2.2e-30 105.7 2.6 3.6e-30 105.0 1.8 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 KFY03680.1 - 2.8e-21 75.0 0.3 8.5e-21 73.5 0.2 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 KFY03680.1 - 3.7e-17 61.5 0.6 8.2e-17 60.4 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KFY03680.1 - 8.8e-10 39.1 0.2 9.2e-09 35.8 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KFY03680.1 - 4.1e-07 30.3 0.3 9.1e-07 29.1 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain FTA4 PF13093.1 KFY03681.1 - 1.5e-41 142.2 0.8 1.1e-40 139.3 0.6 1.9 1 1 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 CR6_interact PF10147.4 KFY03681.1 - 0.048 12.9 1.9 0.085 12.1 1.3 1.4 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 RTA1 PF04479.8 KFY03682.1 - 2.3e-40 138.4 4.7 2.3e-40 138.4 3.2 1.4 1 1 1 2 2 2 1 RTA1 like protein Retro_M PF02813.9 KFY03682.1 - 0.12 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Retroviral M domain Fungal_trans_2 PF11951.3 KFY03683.1 - 1.5e-09 36.9 5.0 2.2e-09 36.4 3.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY03683.1 - 7.1e-09 35.4 6.9 1.2e-08 34.7 4.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain INO80_Ies4 PF08193.6 KFY03683.1 - 0.046 13.6 1.6 0.071 13.0 1.1 1.2 1 0 0 1 1 1 0 INO80 complex subunit Ies4 EamA PF00892.15 KFY03685.1 - 2.3e-08 34.0 26.1 3.7e-05 23.7 0.5 2.7 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 KFY03685.1 - 8.2e-06 26.0 2.0 8.2e-06 26.0 1.4 3.2 3 0 0 3 3 3 1 Multidrug resistance efflux transporter DUF1469 PF07332.6 KFY03685.1 - 0.00091 18.9 5.5 0.019 14.6 0.5 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1469) TPT PF03151.11 KFY03685.1 - 0.025 14.2 10.6 0.35 10.5 4.3 2.8 2 0 0 2 2 2 0 Triose-phosphate Transporter family SCP2 PF02036.12 KFY03686.1 - 5.1e-23 81.3 1.0 6.8e-23 80.8 0.7 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 KFY03686.1 - 8.1e-07 29.0 0.2 1.2e-06 28.4 0.2 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal ADH_zinc_N PF00107.21 KFY03692.1 - 1.9e-24 85.6 0.8 3.1e-24 84.9 0.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFY03692.1 - 0.00013 22.8 0.1 0.00044 21.1 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KFY03692.1 - 0.00048 20.6 0.8 0.003 18.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain AlaDh_PNT_C PF01262.16 KFY03692.1 - 0.0006 19.4 0.2 0.0015 18.1 0.1 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 KFY03692.1 - 0.0014 18.0 0.0 0.0037 16.6 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 KFY03692.1 - 0.037 13.1 0.5 0.19 10.8 0.0 2.2 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_31 PF13847.1 KFY03692.1 - 0.05 13.1 0.0 0.091 12.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KFY03692.1 - 0.074 13.5 0.3 0.43 11.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Mitofilin PF09731.4 KFY03692.1 - 3 6.3 29.7 4.3 5.8 20.6 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein F-box-like PF12937.2 KFY03693.1 - 0.0052 16.4 0.2 0.016 14.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like DUF3135 PF11333.3 KFY03693.1 - 0.15 12.2 0.1 0.4 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) Peptidase_A4 PF01828.12 KFY03694.1 - 4.2e-44 150.1 8.9 7.3e-44 149.3 6.2 1.4 1 0 0 1 1 1 1 Peptidase A4 family EHN PF06441.7 KFY03694.1 - 7.5e-18 64.4 0.3 8.5e-16 57.8 0.1 2.6 1 1 1 2 2 2 2 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KFY03694.1 - 7.1e-13 48.9 0.0 2.7e-12 47.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY03694.1 - 1.4e-10 41.1 0.0 3.4e-10 39.8 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ecm33 PF12454.3 KFY03694.1 - 0.032 14.1 1.1 1.7 8.5 0.0 2.6 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein bZIP_1 PF00170.16 KFY03694.1 - 0.036 14.0 8.7 0.039 13.9 2.8 2.3 2 0 0 2 2 2 0 bZIP transcription factor Fungal_trans PF04082.13 KFY03695.1 - 1.5e-29 102.7 0.0 3.2e-29 101.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY03695.1 - 2.2e-11 43.4 10.0 5e-11 42.3 6.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mtf2_C PF14061.1 KFY03695.1 - 0.015 15.1 0.1 0.035 14.0 0.1 1.6 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 SLAC1 PF03595.12 KFY03696.1 - 1.7e-60 204.4 45.4 1.9e-60 204.2 31.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Ost4 PF10215.4 KFY03696.1 - 0.054 13.0 5.7 1.3 8.5 0.7 2.8 2 0 0 2 2 2 0 Oligosaccaryltransferase Tom22 PF04281.8 KFY03696.1 - 4.2 6.8 5.2 0.94 9.0 1.2 1.7 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Zn_clus PF00172.13 KFY03697.1 - 1.1e-07 31.6 6.1 2.3e-07 30.6 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFY03697.1 - 5.3e-05 22.2 0.0 0.00012 21.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain HSF_DNA-bind PF00447.12 KFY03697.1 - 0.017 15.2 0.5 5.2 7.2 0.0 2.5 2 0 0 2 2 2 0 HSF-type DNA-binding Sulfatase PF00884.18 KFY03698.1 - 1.5e-70 237.8 0.0 2e-70 237.4 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KFY03698.1 - 0.12 11.6 0.1 0.33 10.2 0.0 1.7 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sugar_tr PF00083.19 KFY03699.1 - 2e-98 329.9 18.0 2.3e-98 329.7 12.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY03699.1 - 8.3e-22 77.3 29.0 7.5e-21 74.2 8.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFY03699.1 - 1.7e-05 23.4 23.0 0.014 13.8 4.6 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein DUF1228 PF06779.9 KFY03699.1 - 1.6 8.7 7.9 0.11 12.5 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Ras PF00071.17 KFY03700.1 - 2.3e-40 137.6 0.0 3.5e-40 137.0 0.0 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KFY03700.1 - 1.3e-14 54.7 0.0 1.8e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFY03700.1 - 2.3e-10 40.0 0.0 3.2e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KFY03700.1 - 0.00024 20.3 0.0 0.00032 19.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KFY03700.1 - 0.0015 18.4 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFY03700.1 - 0.014 14.6 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KFY03700.1 - 0.014 14.8 0.0 0.51 9.8 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 KFY03700.1 - 0.015 15.0 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 KFY03700.1 - 0.016 15.5 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 KFY03700.1 - 0.021 14.8 0.0 0.049 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KFY03700.1 - 0.021 14.3 0.1 0.088 12.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KFY03700.1 - 0.022 14.8 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFY03700.1 - 0.024 14.4 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFY03700.1 - 0.029 14.0 0.0 0.059 13.0 0.0 1.5 2 0 0 2 2 1 0 NACHT domain DUF258 PF03193.11 KFY03700.1 - 0.035 13.2 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 KFY03700.1 - 0.098 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KFY03700.1 - 0.17 11.7 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KFY03700.1 - 0.19 11.1 0.0 0.38 10.1 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.15 KFY03700.1 - 0.19 10.4 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit adh_short PF00106.20 KFY03701.1 - 1.2e-22 80.5 0.2 1.6e-22 80.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFY03701.1 - 3.5e-10 39.8 0.1 7.2e-10 38.8 0.0 1.6 1 1 0 1 1 1 1 KR domain Glyco_hydro_10 PF00331.15 KFY03702.1 - 1.1e-90 303.9 5.3 1.4e-90 303.5 3.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Sulfate_transp PF00916.15 KFY03703.1 - 2.2e-41 141.7 0.7 5.5e-41 140.4 0.5 1.7 1 0 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 KFY03703.1 - 1.9e-17 62.8 0.0 4.1e-17 61.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 KFY03703.1 - 2.4e-09 36.6 0.0 4.1e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 STAS domain Sld5 PF05916.6 KFY03704.1 - 5.5e-13 49.1 0.1 1.6e-12 47.7 0.0 1.8 2 0 0 2 2 2 1 GINS complex protein DUF2365 PF10157.4 KFY03704.1 - 0.061 13.2 0.1 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2365) HMG_box PF00505.14 KFY03705.1 - 1.6e-11 44.2 0.1 1.6e-11 44.2 0.1 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFY03705.1 - 0.0012 19.2 0.1 0.0012 19.2 0.1 2.2 2 0 0 2 2 2 1 HMG-box domain MAT_Alpha1 PF04769.7 KFY03705.1 - 0.069 12.4 0.0 0.069 12.4 0.0 2.0 2 0 0 2 2 2 0 Mating-type protein MAT alpha 1 Glyco_transf_41 PF13844.1 KFY03707.1 - 6.2e-95 317.8 0.0 2.5e-51 174.1 0.0 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 41 TPR_11 PF13414.1 KFY03707.1 - 7.8e-23 79.9 10.1 4.1e-09 35.9 0.1 4.7 4 0 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 KFY03707.1 - 8.8e-18 63.0 7.2 0.00011 21.6 0.0 5.6 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 KFY03707.1 - 2.8e-15 54.9 10.4 0.0057 16.4 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 KFY03707.1 - 4.6e-13 48.8 12.0 0.00048 20.0 0.2 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFY03707.1 - 6.2e-11 41.9 3.1 0.015 15.8 0.0 5.6 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 KFY03707.1 - 6.7e-11 41.4 6.0 0.1 12.8 0.3 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFY03707.1 - 8.4e-11 40.8 3.5 0.0013 18.3 0.0 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFY03707.1 - 1.2e-10 40.3 3.7 0.011 15.4 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFY03707.1 - 4.2e-10 40.0 7.0 0.0015 19.1 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 KFY03707.1 - 1.6e-09 37.3 7.4 0.036 13.9 0.1 5.4 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 KFY03707.1 - 1e-08 35.3 3.2 0.0025 18.1 0.3 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 KFY03707.1 - 0.00025 21.1 1.2 0.19 11.8 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 KFY03707.1 - 0.0022 17.1 0.1 0.063 12.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_5 PF12688.2 KFY03707.1 - 0.0079 16.2 1.3 0.04 13.9 0.2 2.6 3 0 0 3 3 3 1 Tetratrico peptide repeat BTAD PF03704.12 KFY03707.1 - 0.036 14.3 0.5 3.9 7.7 0.0 2.7 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.1 KFY03707.1 - 0.044 14.2 4.2 18 6.0 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 KFY03707.1 - 0.065 13.1 3.4 0.64 9.9 0.2 3.2 4 0 0 4 4 2 0 Tetratricopeptide repeat Ribosomal_L11_N PF03946.9 KFY03708.1 - 7.8e-18 63.6 0.0 1.2e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KFY03708.1 - 1.8e-11 43.9 0.3 3e-11 43.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain IF2_N PF04760.10 KFY03708.1 - 0.0046 16.5 0.2 0.19 11.4 0.0 2.6 1 1 1 2 2 2 2 Translation initiation factor IF-2, N-terminal region Fibrillarin PF01269.12 KFY03709.1 - 2.9e-107 356.8 0.0 3.5e-107 356.5 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 KFY03709.1 - 1.3e-05 24.8 0.0 2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 KFY03709.1 - 0.0099 15.4 0.1 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KFY03709.1 - 0.047 13.2 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Dam PF05869.6 KFY03710.1 - 0.0018 17.7 5.2 6.6 6.1 0.1 4.3 4 0 0 4 4 4 4 DNA N-6-adenine-methyltransferase (Dam) TPR_1 PF00515.23 KFY03711.1 - 7.8e-15 53.7 3.5 7.5e-06 25.3 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 KFY03711.1 - 4.8e-14 51.7 0.6 9e-09 34.8 0.0 3.3 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 KFY03711.1 - 4.2e-13 48.1 2.7 0.00014 21.4 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat PB1 PF00564.19 KFY03711.1 - 1.2e-07 31.2 0.4 2.4e-07 30.3 0.3 1.5 1 0 0 1 1 1 1 PB1 domain TPR_8 PF13181.1 KFY03711.1 - 1.7e-07 30.4 0.8 0.015 15.0 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFY03711.1 - 3.4e-07 30.1 0.2 0.00032 20.5 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KFY03711.1 - 3.4e-06 26.4 0.2 0.00014 21.4 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFY03711.1 - 1.6e-05 25.0 0.1 8.7 7.0 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KFY03711.1 - 0.0009 19.8 0.4 0.024 15.2 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFY03711.1 - 0.0014 18.6 0.5 0.052 13.7 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFY03711.1 - 0.0072 16.8 0.1 0.64 10.8 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFY03711.1 - 0.011 15.5 0.1 5.4 6.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_L13 PF00572.13 KFY03712.1 - 1.1e-39 135.4 0.0 1.5e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Bromodomain PF00439.20 KFY03712.1 - 0.063 13.2 0.0 0.23 11.3 0.0 1.8 1 1 0 1 1 1 0 Bromodomain NinG PF05766.7 KFY03712.1 - 0.075 12.7 0.0 0.14 11.8 0.0 1.4 1 1 1 2 2 2 0 Bacteriophage Lambda NinG protein Uricase PF01014.13 KFY03713.1 - 5e-85 282.5 1.8 1.8e-45 154.3 0.7 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.14 KFY03713.1 - 0.032 13.8 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme RICTOR_N PF14664.1 KFY03714.1 - 8.2e-140 465.6 5.3 3.6e-139 463.4 1.4 2.7 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 KFY03714.1 - 9.7e-87 289.7 0.6 1.2e-85 286.1 0.1 2.8 2 1 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 KFY03714.1 - 2.9e-42 143.2 0.0 1.1e-40 138.1 0.0 3.3 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 KFY03714.1 - 1.5e-29 101.7 2.1 9e-28 96.0 0.0 4.3 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 KFY03714.1 - 4.4e-12 45.5 9.7 1.5e-11 43.8 6.7 1.9 1 0 0 1 1 1 1 Hr1 repeat HEAT_2 PF13646.1 KFY03714.1 - 0.00012 22.2 2.1 3.9 7.8 0.0 5.5 5 0 0 5 5 5 1 HEAT repeats IncA PF04156.9 KFY03714.1 - 0.034 13.7 4.2 0.069 12.7 2.9 1.4 1 0 0 1 1 1 0 IncA protein DUF2443 PF10398.4 KFY03714.1 - 0.057 13.2 0.7 0.18 11.6 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Noelin-1 PF12308.3 KFY03714.1 - 0.065 13.0 1.2 0.17 11.7 0.8 1.7 1 0 0 1 1 1 0 Neurogenesis glycoprotein HOOK PF05622.7 KFY03714.1 - 0.12 10.1 7.9 0.21 9.3 4.3 1.9 2 0 0 2 2 2 0 HOOK protein PCI PF01399.22 KFY03715.1 - 4.7e-14 52.5 0.1 6.5e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 PCI domain API5 PF05918.6 KFY03715.1 - 0.39 9.1 2.6 0.53 8.7 1.8 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) MutS_V PF00488.16 KFY03717.1 - 1.8e-96 322.1 0.0 2.8e-96 321.4 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFY03717.1 - 3.6e-35 121.6 1.1 7.8e-35 120.5 0.7 1.6 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 KFY03717.1 - 2e-20 73.2 0.0 5.9e-20 71.7 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_I PF01624.15 KFY03717.1 - 2.9e-19 69.1 0.3 1.3e-18 67.1 0.0 2.3 3 0 0 3 3 3 1 MutS domain I MutS_IV PF05190.13 KFY03717.1 - 2.1e-16 59.8 2.1 7.2e-16 58.1 1.4 2.0 1 0 0 1 1 1 1 MutS family domain IV Peptidase_M16 PF00675.15 KFY03717.1 - 0.018 14.7 0.1 0.087 12.5 0.0 2.1 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) SCAN PF02023.12 KFY03717.1 - 0.048 13.1 2.0 0.067 12.6 0.5 1.9 2 0 0 2 2 2 0 SCAN domain SYS1 PF09801.4 KFY03719.1 - 6e-50 169.0 12.0 6.9e-50 168.8 8.3 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network COX6B PF02297.12 KFY03720.1 - 1.8e-25 88.7 5.2 2.3e-25 88.3 3.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 KFY03720.1 - 0.052 13.6 1.4 0.098 12.7 1.0 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 AA_permease_2 PF13520.1 KFY03722.1 - 6e-38 130.4 22.5 7.2e-38 130.2 15.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFY03722.1 - 1.8e-14 52.9 16.4 2.1e-14 52.7 11.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1980 PF09323.5 KFY03722.1 - 0.17 11.6 2.2 2 8.1 1.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) DUF2206 PF09971.4 KFY03722.1 - 1.5 7.5 7.4 0.19 10.4 0.1 2.5 3 1 0 3 3 3 0 Predicted membrane protein (DUF2206) YlaC PF10777.4 KFY03722.1 - 7.3 6.1 5.7 1.3 8.5 0.0 2.5 3 0 0 3 3 3 0 Inner membrane protein YlaC Na_Ca_ex PF01699.19 KFY03723.1 - 3.5e-27 94.7 34.2 1.2e-15 57.2 9.4 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein IncA PF04156.9 KFY03723.1 - 0.015 14.9 0.7 0.086 12.4 0.0 2.4 2 0 0 2 2 2 0 IncA protein CVNH PF08881.5 KFY03724.1 - 3.2e-15 56.2 0.6 2e-09 37.5 0.0 2.0 1 1 1 2 2 2 2 CVNH domain Sedlin_N PF04628.8 KFY03726.1 - 4.4e-36 123.6 0.0 6.7e-36 123.0 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF77 PF01910.12 KFY03726.1 - 5.4e-31 106.1 0.1 8.5e-31 105.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF77 L31 PF09784.4 KFY03727.1 - 1.9e-43 146.7 3.4 2.1e-43 146.5 2.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 YpzI PF14140.1 KFY03727.1 - 0.079 12.4 2.2 0.59 9.6 0.1 2.2 2 0 0 2 2 2 0 YpzI-like protein RRM_1 PF00076.17 KFY03728.1 - 9.7e-15 53.9 0.0 1.4e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY03728.1 - 1.1e-10 41.3 0.0 1.6e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFY03728.1 - 1.1e-07 31.6 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SRP72 PF08492.7 KFY03729.1 - 1.2e-12 47.9 6.8 1.2e-12 47.9 4.7 2.6 2 0 0 2 2 2 1 SRP72 RNA-binding domain Nup88 PF10168.4 KFY03729.1 - 2.3e-05 22.5 1.5 0.012 13.4 0.0 2.4 2 0 0 2 2 2 2 Nuclear pore component Apc3 PF12895.2 KFY03729.1 - 0.0028 17.7 0.9 0.27 11.3 0.1 3.3 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 THOC7 PF05615.8 KFY03729.1 - 0.0054 17.0 2.1 0.019 15.2 1.4 1.9 1 0 0 1 1 1 1 Tho complex subunit 7 TPR_2 PF07719.12 KFY03729.1 - 0.012 15.4 1.7 17 5.6 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat CNP1 PF08750.6 KFY03729.1 - 0.019 14.6 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 CNP1-like family TPR_19 PF14559.1 KFY03729.1 - 0.034 14.4 11.0 8.7 6.7 0.1 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF948 PF06103.6 KFY03729.1 - 0.24 11.2 1.3 7.5 6.4 0.0 3.5 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Hormone_1 PF00103.15 KFY03729.1 - 0.27 10.5 4.3 0.93 8.7 0.3 2.7 2 1 1 3 3 3 0 Somatotropin hormone family TPR_16 PF13432.1 KFY03729.1 - 2.2 9.0 10.4 0.94 10.2 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Ubiq_cyt_C_chap PF03981.7 KFY03730.1 - 1.2e-39 135.4 0.4 1.9e-39 134.7 0.2 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Epimerase PF01370.16 KFY03732.1 - 2.6e-17 63.0 0.0 4.7e-17 62.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KFY03732.1 - 9.6e-10 37.7 0.0 1.4e-08 34.0 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 KFY03732.1 - 5.1e-08 31.9 0.0 1.2e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFY03732.1 - 1.8e-05 24.8 0.0 8.3e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KFY03732.1 - 0.0001 22.2 0.0 0.00022 21.2 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KFY03732.1 - 0.014 15.0 0.0 0.037 13.6 0.0 1.6 1 1 0 1 1 1 0 KR domain DEAD PF00270.24 KFY03733.1 - 2.5e-41 140.9 1.7 4.2e-41 140.2 1.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFY03733.1 - 1.8e-22 78.9 0.0 2.9e-11 43.0 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KFY03733.1 - 5e-05 23.2 0.5 0.00013 21.8 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Peptidase_M19 PF01244.16 KFY03733.1 - 0.049 12.5 0.1 0.099 11.5 0.1 1.4 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) SH3_9 PF14604.1 KFY03736.1 - 6.7e-11 41.6 0.3 2.3e-10 39.9 0.2 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KFY03736.1 - 6.9e-10 38.1 0.2 1.7e-09 36.8 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KFY03736.1 - 2e-09 36.7 0.1 4.8e-09 35.5 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain RPAP2_Rtr1 PF04181.8 KFY03737.1 - 7.1e-16 58.0 0.0 1.2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family Ribosomal_S17e PF00833.13 KFY03738.1 - 4.1e-59 197.6 0.5 5e-59 197.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 KFY03738.1 - 0.074 13.7 0.0 0.1 13.2 0.0 1.2 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal Mit_ribos_Mrp51 PF11709.3 KFY03739.1 - 3.8e-82 276.0 0.1 4.6e-82 275.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit DUF3145 PF11343.3 KFY03739.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3145) Takusan PF04822.8 KFY03739.1 - 0.064 13.0 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Takusan dCMP_cyt_deam_1 PF00383.17 KFY03740.1 - 1.2e-13 50.5 0.1 2.1e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 KFY03740.1 - 0.0017 17.9 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain XOO_2897-deam PF14440.1 KFY03740.1 - 0.042 13.5 0.1 0.074 12.7 0.0 1.5 1 1 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase CD99L2 PF12301.3 KFY03742.1 - 0.0068 16.1 0.5 0.0068 16.1 0.4 2.6 3 0 0 3 3 3 1 CD99 antigen like protein 2 Chitin_synth_1 PF01644.12 KFY03743.1 - 3.6e-86 287.0 0.2 6.8e-86 286.1 0.2 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KFY03743.1 - 6.4e-33 112.2 0.1 1.3e-32 111.2 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KFY03743.1 - 9.6e-25 86.9 4.0 2.3e-21 75.8 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KFY03743.1 - 1.7e-09 37.7 3.8 7.6e-09 35.5 2.6 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KFY03743.1 - 0.00041 20.2 0.0 0.00081 19.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF1993 PF09351.5 KFY03744.1 - 3.6e-49 166.7 0.0 4e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Pyr_redox_2 PF07992.9 KFY03745.1 - 4.2e-13 49.6 0.3 6.3e-13 49.0 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFY03745.1 - 1.2e-07 32.0 0.3 1.7e-05 25.1 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFY03745.1 - 1.4e-06 28.5 0.2 0.0074 16.3 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFY03745.1 - 0.0018 18.0 0.8 3.6 7.3 0.0 4.0 5 0 0 5 5 5 1 FAD-NAD(P)-binding DAO PF01266.19 KFY03745.1 - 0.018 13.9 1.7 0.93 8.3 0.0 3.0 2 1 1 3 3 3 0 FAD dependent oxidoreductase Fungal_trans_2 PF11951.3 KFY03746.1 - 1.7e-44 152.0 5.9 2e-44 151.7 4.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY03746.1 - 6.1e-10 38.8 6.5 1.2e-09 37.8 4.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.14 KFY03747.1 - 1.2e-33 116.5 0.0 4.7e-28 98.1 0.0 2.7 2 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 KFY03747.1 - 5.2e-29 101.3 0.0 8.3e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KFY03747.1 - 4.8e-05 23.3 0.3 0.00014 21.8 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFY03747.1 - 0.00071 18.5 0.0 0.0013 17.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFY03747.1 - 0.00083 18.3 0.0 0.017 14.0 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KFY03747.1 - 0.0082 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein ApbA PF02558.11 KFY03747.1 - 0.016 14.6 0.4 0.038 13.4 0.2 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 KFY03747.1 - 0.022 14.6 0.1 0.083 12.7 0.0 2.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFY03747.1 - 0.083 11.3 0.6 0.12 10.7 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Sugar_tr PF00083.19 KFY03748.1 - 4.8e-116 388.0 22.7 5.5e-116 387.8 15.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY03748.1 - 3.1e-27 95.2 22.2 1.5e-20 73.2 1.8 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4094 PF13334.1 KFY03748.1 - 0.03 14.7 0.0 4.6 7.6 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) ABC2_membrane PF01061.19 KFY03749.1 - 3.3e-89 297.6 58.6 1.1e-46 158.6 13.0 3.2 4 0 0 4 4 2 2 ABC-2 type transporter ABC_tran PF00005.22 KFY03749.1 - 2.4e-38 131.5 0.1 3.4e-19 69.5 0.0 2.9 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 KFY03749.1 - 7.3e-29 99.4 1.2 7.5e-25 86.5 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter AAA_25 PF13481.1 KFY03749.1 - 9.8e-07 28.3 0.1 0.061 12.7 0.1 2.8 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 KFY03749.1 - 1.1e-06 28.5 0.0 0.0016 18.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 KFY03749.1 - 3.1e-06 27.3 1.7 0.039 13.9 0.0 4.0 3 1 0 4 4 4 1 AAA domain ABC_trans_N PF14510.1 KFY03749.1 - 6.3e-06 26.1 0.1 1.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal FtsK_SpoIIIE PF01580.13 KFY03749.1 - 1.5e-05 24.6 0.1 0.11 11.9 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_18 PF13238.1 KFY03749.1 - 1.8e-05 25.0 0.0 0.005 17.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 KFY03749.1 - 2.6e-05 23.4 0.0 0.00072 18.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 KFY03749.1 - 2.8e-05 23.6 0.2 0.001 18.5 0.0 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 KFY03749.1 - 5.9e-05 23.2 0.0 0.097 12.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFY03749.1 - 0.00014 21.9 0.5 0.0087 16.0 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KFY03749.1 - 0.00018 20.9 0.5 0.16 11.5 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KFY03749.1 - 0.00072 19.4 0.2 0.27 11.2 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.1 KFY03749.1 - 0.0012 18.8 1.4 0.0029 17.6 0.1 2.3 3 0 0 3 3 1 1 AAA domain UPF0079 PF02367.12 KFY03749.1 - 0.0014 18.2 4.9 0.077 12.6 0.3 3.3 3 0 0 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KFY03749.1 - 0.0016 18.1 0.5 0.46 10.1 0.3 2.4 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.1 KFY03749.1 - 0.0035 16.9 0.1 0.28 10.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFY03749.1 - 0.0036 18.0 0.0 0.068 14.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KFY03749.1 - 0.005 16.3 1.4 1.6 8.0 0.0 2.7 3 0 0 3 3 2 2 AAA-like domain SMC_N PF02463.14 KFY03749.1 - 0.005 16.0 0.4 0.039 13.1 0.0 2.5 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain Miro PF08477.8 KFY03749.1 - 0.015 15.7 0.0 1.1 9.8 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 KFY03749.1 - 0.017 15.2 0.3 10 6.2 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 KFY03749.1 - 0.022 13.6 0.0 3.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Septin PF00735.13 KFY03749.1 - 0.039 12.9 0.4 0.33 9.9 0.1 2.2 2 0 0 2 2 2 0 Septin AAA_19 PF13245.1 KFY03749.1 - 0.051 13.3 0.3 8.6 6.1 0.1 2.7 2 0 0 2 2 2 0 Part of AAA domain RNA_helicase PF00910.17 KFY03749.1 - 0.056 13.6 0.0 9.2 6.4 0.0 3.2 3 0 0 3 3 3 0 RNA helicase NB-ARC PF00931.17 KFY03749.1 - 0.091 11.6 1.1 3.9 6.2 0.4 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.1 KFY03749.1 - 0.11 11.5 0.0 6 5.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 KFY03749.1 - 0.17 11.3 0.5 0.47 9.9 0.2 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Glyco_transf_36 PF06165.6 KFY03750.1 - 1.5e-21 76.2 0.0 3.5e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 36 GDE_C PF06202.9 KFY03750.1 - 0.0031 16.3 0.0 0.0068 15.1 0.0 1.5 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Bac_rhamnosid PF05592.6 KFY03750.1 - 0.0048 15.1 0.2 0.0093 14.2 0.0 1.4 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase GT36_AF PF06205.6 KFY03750.1 - 0.0055 16.4 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase 36 associated family AAA PF00004.24 KFY03751.1 - 2.6e-16 60.0 0.0 9.9e-16 58.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KFY03751.1 - 5.9e-05 22.7 0.1 0.00014 21.5 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KFY03751.1 - 0.00023 21.3 0.3 0.0022 18.1 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 KFY03751.1 - 0.0012 18.5 0.0 0.0029 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KFY03751.1 - 0.0083 16.9 0.0 0.0083 16.9 0.0 3.1 3 2 1 4 4 4 1 AAA domain AAA_33 PF13671.1 KFY03751.1 - 0.029 14.2 0.0 0.067 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KFY03751.1 - 0.03 14.3 0.3 0.11 12.4 0.1 2.0 1 1 1 2 2 2 0 AAA ATPase domain SOBP PF15279.1 KFY03751.1 - 4.8 7.4 16.9 10 6.4 11.7 1.6 1 0 0 1 1 1 0 Sine oculis-binding protein RRM_5 PF13893.1 KFY03752.1 - 0.0001 22.0 0.0 0.0051 16.6 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY03752.1 - 0.018 15.0 0.0 0.074 13.0 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FTA2 PF13095.1 KFY03760.1 - 0.00016 21.3 0.0 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.20 KFY03760.1 - 0.00038 19.7 0.0 0.076 12.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase PF00069.20 KFY03761.1 - 0.16 11.1 0.0 0.34 9.9 0.0 1.6 1 0 0 1 1 1 0 Protein kinase domain ABC2_membrane PF01061.19 KFY03763.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 ABC-2 type transporter WD40 PF00400.27 KFY03766.1 - 2.2e-34 116.0 1.9 2.8e-11 42.8 0.0 7.7 7 1 0 7 7 7 5 WD domain, G-beta repeat PD40 PF07676.7 KFY03766.1 - 3.1e-05 23.5 1.3 30 4.4 0.0 6.6 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 KFY03766.1 - 0.00058 19.0 0.6 0.18 10.8 0.0 3.4 4 0 0 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 KFY03766.1 - 0.054 11.6 1.8 0.89 7.6 0.1 2.4 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 KFY03766.1 - 0.19 10.5 0.0 1.3 7.7 0.0 1.9 1 1 0 2 2 2 0 Coatomer WD associated region Ribosomal_L18e PF00828.14 KFY03770.1 - 1.1e-14 54.8 0.1 1.1e-14 54.8 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Mito_carr PF00153.22 KFY03771.1 - 9.2e-75 246.4 5.5 1.2e-25 89.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4219 PF13961.1 KFY03772.1 - 0.15 11.5 0.9 0.2 11.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) RRM_1 PF00076.17 KFY03773.1 - 6.4e-12 44.9 0.0 9e-12 44.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY03773.1 - 6e-08 32.5 0.0 9.7e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFY03773.1 - 1.2e-07 31.4 0.0 1.7e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFY03773.1 - 0.0038 16.9 0.0 0.0058 16.3 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif CH PF00307.26 KFY03774.1 - 3.9e-63 210.2 0.0 2.2e-19 69.4 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 KFY03774.1 - 1.1e-06 28.7 0.2 0.00011 22.2 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KFY03774.1 - 0.00022 20.2 2.0 0.16 11.3 0.3 3.5 3 0 0 3 3 3 2 EF hand CAMSAP_CH PF11971.3 KFY03774.1 - 0.0071 15.9 0.0 16 5.2 0.0 3.6 3 0 0 3 3 3 1 CAMSAP CH domain EF-hand_6 PF13405.1 KFY03774.1 - 0.011 15.5 4.2 0.081 12.8 0.1 3.3 3 0 0 3 3 3 0 EF-hand domain EF-hand_5 PF13202.1 KFY03774.1 - 0.22 10.9 3.4 0.51 9.7 0.3 2.9 2 0 0 2 2 2 0 EF hand DWNN PF08783.6 KFY03775.1 - 1.4e-30 105.0 0.1 2.3e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 KFY03775.1 - 0.00013 21.3 2.5 0.00039 19.8 1.7 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KFY03775.1 - 0.00087 19.1 1.3 0.0017 18.1 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle U-box PF04564.10 KFY03775.1 - 0.0022 17.9 0.1 0.0061 16.4 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 KFY03775.1 - 0.035 13.6 5.0 0.079 12.4 3.5 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.9 KFY03775.1 - 0.066 12.6 1.3 0.21 11.1 0.9 1.8 1 1 0 1 1 1 0 Rad50 zinc hook motif zf-RING_6 PF14835.1 KFY03775.1 - 0.15 11.9 1.3 0.26 11.0 0.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 KFY03775.1 - 0.15 11.7 5.5 0.3 10.6 3.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KFY03775.1 - 0.37 10.7 9.7 1.2 9.0 6.7 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KFY03775.1 - 0.53 9.9 9.2 1.1 8.9 6.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFY03775.1 - 0.93 9.5 14.6 0.095 12.7 5.9 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KFY03775.1 - 1.6 8.4 11.6 0.16 11.7 4.3 2.0 2 0 0 2 2 2 0 zinc-RING finger domain His_biosynth PF00977.16 KFY03776.1 - 1.1e-45 155.7 0.9 5.1e-45 153.5 0.6 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 KFY03776.1 - 7.5e-28 97.2 0.0 1.2e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 KFY03776.1 - 2.4e-11 43.5 0.0 4.9e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 KFY03776.1 - 2.4e-08 33.7 0.0 4.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 KFY03776.1 - 0.0027 17.1 0.0 0.0054 16.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 KFY03776.1 - 0.01 15.3 0.2 0.24 10.8 0.0 2.3 2 0 0 2 2 2 0 DJ-1/PfpI family Peptidase_S51 PF03575.12 KFY03776.1 - 0.024 14.4 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 dCMP_cyt_deam_1 PF00383.17 KFY03777.1 - 1e-27 95.7 1.1 1.8e-27 94.9 0.7 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 KFY03777.1 - 1e-05 26.3 0.0 1.7e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFY03777.1 - 0.00019 21.7 0.0 0.00037 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain CoaE PF01121.15 KFY03777.1 - 0.0016 17.9 0.0 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 Dephospho-CoA kinase DUF1338 PF07063.8 KFY03777.1 - 0.12 11.4 0.2 0.59 9.1 0.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1338) ThiF PF00899.16 KFY03778.1 - 1e-28 99.8 0.0 1.7e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 KFY03778.1 - 0.0008 19.5 0.0 0.0073 16.4 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Toprim PF01751.17 KFY03778.1 - 0.019 14.9 0.0 0.95 9.4 0.0 2.6 2 0 0 2 2 2 0 Toprim domain 2-Hacid_dh_C PF02826.14 KFY03778.1 - 0.15 11.2 0.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MIT PF04212.13 KFY03779.1 - 2.5e-10 40.1 0.4 5.6e-10 38.9 0.2 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain PXA PF02194.10 KFY03780.1 - 3.3e-29 101.7 0.8 5e-29 101.1 0.0 1.7 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 KFY03780.1 - 5.4e-20 71.5 0.0 5.4e-20 71.5 0.0 2.5 3 0 0 3 3 3 1 Sorting nexin C terminal PX PF00787.19 KFY03780.1 - 1.3e-08 34.5 0.0 9.1e-08 31.8 0.0 2.2 2 0 0 2 2 2 1 PX domain Flagellin_N PF00669.15 KFY03780.1 - 0.14 11.9 3.1 0.37 10.5 2.1 1.7 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region PC4 PF02229.11 KFY03781.1 - 3e-18 64.8 0.0 5.1e-18 64.0 0.0 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DDHD PF02862.12 KFY03782.1 - 2.2e-74 250.0 0.6 1.6e-73 247.3 0.0 2.5 2 1 0 2 2 2 1 DDHD domain DUF676 PF05057.9 KFY03782.1 - 0.082 12.1 0.2 0.62 9.3 0.0 2.4 3 0 0 3 3 3 0 Putative serine esterase (DUF676) LCAT PF02450.10 KFY03782.1 - 0.15 11.0 0.0 0.29 10.0 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase MGC-24 PF05283.6 KFY03787.1 - 0.16 11.7 5.3 2.4 7.9 0.5 2.1 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) DUF1180 PF06679.7 KFY03788.1 - 0.014 15.3 2.7 0.014 15.3 1.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) PIH1 PF08190.7 KFY03788.1 - 0.74 9.2 5.1 0.84 9.0 3.5 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 DUF4337 PF14235.1 KFY03790.1 - 0.0075 16.1 12.8 0.01 15.6 8.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4337) HAUS6_N PF14661.1 KFY03790.1 - 0.011 15.1 12.5 0.013 14.9 8.6 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus CAF-1_p150 PF11600.3 KFY03790.1 - 0.036 13.4 33.0 0.039 13.3 22.9 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TEX19 PF15553.1 KFY03790.1 - 0.15 11.9 3.9 0.18 11.6 2.7 1.1 1 0 0 1 1 1 0 Testis-expressed protein 19 Asp-B-Hydro_N PF05279.6 KFY03790.1 - 0.37 10.5 13.8 0.42 10.4 9.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region RAP1 PF07218.6 KFY03790.1 - 0.44 8.5 12.1 0.5 8.3 8.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) GAGA_bind PF06217.7 KFY03790.1 - 0.61 9.9 14.4 0.7 9.7 10.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family FLO_LFY PF01698.11 KFY03790.1 - 0.71 8.6 12.1 0.8 8.4 8.4 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Folate_carrier PF01770.13 KFY03790.1 - 0.89 7.9 5.1 0.88 8.0 3.5 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF607 PF04678.8 KFY03790.1 - 0.96 9.3 5.1 1.1 9.1 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF607 DUF1510 PF07423.6 KFY03790.1 - 1.1 8.5 16.7 1.2 8.4 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3807 PF12720.2 KFY03790.1 - 1.2 9.3 14.8 1.3 9.1 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF853 PF05872.7 KFY03790.1 - 1.3 7.2 6.2 1.5 7.1 4.3 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) U79_P34 PF03064.11 KFY03790.1 - 1.6 8.2 15.7 1.9 7.9 10.9 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 APG6 PF04111.7 KFY03790.1 - 1.6 7.6 15.5 1.9 7.4 10.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_23 PF13476.1 KFY03790.1 - 1.7 8.9 15.1 2.1 8.6 10.5 1.1 1 0 0 1 1 1 0 AAA domain Paramyxo_ncap PF00973.14 KFY03790.1 - 1.7 7.2 6.7 1.8 7.1 4.6 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Vfa1 PF08432.5 KFY03790.1 - 1.9 8.4 21.5 2.1 8.3 14.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TP53IP5 PF15331.1 KFY03790.1 - 2 8.3 15.4 2.2 8.1 10.7 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 AAA_11 PF13086.1 KFY03790.1 - 2.3 7.7 11.0 2.5 7.5 7.7 1.1 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.7 KFY03790.1 - 3.2 7.5 15.7 3.3 7.5 10.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2151 PF10221.4 KFY03790.1 - 3.3 5.7 13.3 3.5 5.6 9.2 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator DUF342 PF03961.8 KFY03790.1 - 3.4 5.9 14.3 3.8 5.8 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DDHD PF02862.12 KFY03790.1 - 3.5 7.3 10.4 3.8 7.2 7.2 1.1 1 0 0 1 1 1 0 DDHD domain Peptidase_U57 PF05582.7 KFY03790.1 - 5 6.0 9.0 6.2 5.7 6.2 1.2 1 0 0 1 1 1 0 YabG peptidase U57 DUF3987 PF13148.1 KFY03790.1 - 5.3 5.5 17.2 6.2 5.2 11.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) OmpH PF03938.9 KFY03790.1 - 6.3 6.7 24.6 7.7 6.4 16.8 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) RNase_H2-Ydr279 PF09468.5 KFY03790.1 - 6.5 5.8 18.7 7.2 5.7 12.9 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Borrelia_P83 PF05262.6 KFY03790.1 - 6.6 4.8 20.9 7.6 4.6 14.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CT47 PF15623.1 KFY03790.1 - 6.7 6.3 16.4 6.9 6.3 11.3 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 NARP1 PF12569.3 KFY03790.1 - 6.9 5.2 22.8 7.7 5.1 15.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Neur_chan_memb PF02932.11 KFY03790.1 - 7.2 6.4 6.7 7.8 6.3 4.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SR-25 PF10500.4 KFY03790.1 - 7.7 5.9 23.8 13 5.1 16.5 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Hom_end_hint PF05203.11 KFY03790.1 - 7.7 6.1 8.5 8.6 6.0 5.9 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Sec62 PF03839.11 KFY03790.1 - 7.7 5.8 20.4 9 5.6 14.2 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 TMPIT PF07851.8 KFY03790.1 - 8.5 5.3 10.7 8.7 5.3 7.4 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF4407 PF14362.1 KFY03790.1 - 8.9 5.1 9.8 9.6 5.0 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF912 PF06024.7 KFY03791.1 - 0.00097 19.1 0.4 0.014 15.3 0.0 2.6 3 0 0 3 3 3 1 Nucleopolyhedrovirus protein of unknown function (DUF912) OmpH PF03938.9 KFY03791.1 - 0.0018 18.2 4.0 0.0018 18.2 2.8 3.1 3 0 0 3 3 3 2 Outer membrane protein (OmpH-like) SID-1_RNA_chan PF13965.1 KFY03791.1 - 0.0025 16.0 0.9 0.011 13.9 0.2 1.9 1 1 1 2 2 2 2 dsRNA-gated channel SID-1 DUF2207 PF09972.4 KFY03791.1 - 0.0051 15.4 0.5 0.054 12.0 0.2 2.2 2 1 0 3 3 3 1 Predicted membrane protein (DUF2207) Ca_hom_mod PF14798.1 KFY03791.1 - 0.0087 15.0 0.7 0.024 13.6 0.4 1.9 2 0 0 2 2 2 1 Calcium homeostasis modulator T2SM_b PF10741.4 KFY03791.1 - 0.049 13.2 1.2 0.38 10.3 0.2 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b DUF1129 PF06570.6 KFY03791.1 - 0.076 12.3 0.6 7.4 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF4337 PF14235.1 KFY03791.1 - 0.077 12.8 16.7 0.041 13.7 2.4 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) DUF106 PF01956.11 KFY03791.1 - 0.1 12.1 4.7 0.17 11.4 1.4 2.2 2 0 0 2 2 2 0 Integral membrane protein DUF106 V_ATPase_I PF01496.14 KFY03791.1 - 2.2 6.0 4.8 2.5 5.8 1.1 2.4 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 KFY03791.1 - 4.2 7.7 23.1 0.16 12.3 5.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DUF3450 PF11932.3 KFY03791.1 - 4.3 6.5 16.2 5.5 6.1 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) DUF515 PF04415.7 KFY03791.1 - 5.3 5.1 7.4 0.19 9.9 0.1 2.1 3 0 0 3 3 2 0 Protein of unknown function (DUF515) NapE PF06796.6 KFY03791.1 - 5.9 6.2 8.4 0.21 10.9 0.3 2.6 3 0 0 3 3 3 0 Periplasmic nitrate reductase protein NapE YlqD PF11068.3 KFY03791.1 - 6.1 6.8 25.6 0.059 13.4 6.7 3.0 3 0 0 3 3 3 0 YlqD protein DUF4225 PF13988.1 KFY03791.1 - 8.9 5.7 6.8 0.66 9.4 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) Pyr_redox_3 PF13738.1 KFY03792.1 - 2.9e-20 73.2 0.1 8.5e-19 68.4 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFY03792.1 - 6.5e-14 51.0 0.1 8.4e-13 47.3 0.2 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KFY03792.1 - 1.6e-11 43.7 0.0 7.9e-09 34.8 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KFY03792.1 - 3.2e-11 43.4 0.0 2.1e-08 34.3 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFY03792.1 - 3.5e-08 33.3 0.6 5.7e-07 29.4 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFY03792.1 - 1.3e-07 30.8 0.2 2.6e-06 26.5 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFY03792.1 - 5.1e-06 26.7 4.6 0.0041 17.5 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFY03792.1 - 7.1e-05 22.6 4.0 0.0035 17.1 0.5 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 KFY03792.1 - 0.0052 16.4 0.2 0.0091 15.6 0.2 1.4 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KFY03792.1 - 0.0077 14.7 0.6 0.41 9.0 0.1 2.9 3 0 0 3 3 3 1 HI0933-like protein Shikimate_DH PF01488.15 KFY03792.1 - 0.013 15.5 0.3 0.62 10.1 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KFY03792.1 - 0.056 13.6 0.0 1 9.6 0.0 2.4 3 0 0 3 3 2 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 KFY03792.1 - 0.058 12.9 0.1 2.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 KFY03792.1 - 0.07 11.9 0.2 0.07 11.9 0.2 1.8 3 0 0 3 3 3 0 FAD binding domain 2-Hacid_dh_C PF02826.14 KFY03792.1 - 0.2 10.7 0.1 3.8 6.6 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain His_Phos_1 PF00300.17 KFY03793.1 - 6.7e-09 36.0 0.1 9.8e-08 32.2 0.0 2.3 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Peptidase_C13 PF01650.13 KFY03794.1 - 5.1e-41 140.6 0.0 6.5e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family EF-hand_7 PF13499.1 KFY03796.1 - 8.2e-29 99.5 10.2 1.1e-12 47.8 0.5 3.2 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 KFY03796.1 - 1.9e-24 83.0 11.7 3.8e-08 32.0 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 KFY03796.1 - 7.2e-23 78.3 4.0 8.1e-06 25.3 0.1 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 KFY03796.1 - 1.7e-16 58.7 14.2 2.6e-05 23.3 0.0 4.7 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 KFY03796.1 - 1.2e-14 53.5 11.1 1.4e-05 24.6 0.7 4.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 KFY03796.1 - 6.3e-09 35.5 7.4 0.0015 18.1 0.1 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KFY03796.1 - 0.00035 20.4 0.6 0.031 14.2 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 KFY03796.1 - 0.0012 18.8 1.2 0.23 11.5 0.1 2.9 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.6 KFY03796.1 - 0.0035 16.0 0.6 0.28 9.7 0.1 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF1679) EF-hand_10 PF14788.1 KFY03796.1 - 0.0063 16.1 3.1 0.22 11.2 0.1 3.8 4 0 0 4 4 4 1 EF hand EF-hand_2 PF09068.6 KFY03796.1 - 0.015 15.3 0.2 0.9 9.6 0.0 2.8 3 1 0 3 3 3 0 EF hand Mad3_BUB1_II PF08171.6 KFY03796.1 - 0.099 12.5 0.0 0.2 11.5 0.0 1.5 1 1 0 1 1 1 0 Mad3/BUB1 homology region 2 Med4 PF10018.4 KFY03797.1 - 1.3e-41 142.0 5.8 2.1e-41 141.4 4.0 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 TMEM247 PF15444.1 KFY03797.1 - 0.002 18.0 3.3 0.004 16.9 2.3 1.4 1 0 0 1 1 1 1 Transmembrane protein 247 DUF1682 PF07946.9 KFY03797.1 - 1.3 7.8 10.2 1.9 7.2 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Sas10_Utp3 PF04000.10 KFY03798.1 - 3.8e-17 62.2 1.5 7e-17 61.4 1.0 1.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family RcsC PF09456.5 KFY03798.1 - 0.16 11.6 0.6 0.29 10.8 0.4 1.4 1 0 0 1 1 1 0 RcsC Alpha-Beta-Loop (ABL) EMP70 PF02990.11 KFY03799.1 - 2.3e-192 640.1 0.8 2.3e-192 640.1 0.6 1.3 2 0 0 2 2 2 1 Endomembrane protein 70 NfeD PF01957.13 KFY03799.1 - 0.016 15.3 0.0 0.016 15.3 0.0 4.7 2 2 2 5 5 5 0 NfeD-like C-terminal, partner-binding Pectate_lyase PF03211.8 KFY03800.1 - 1.2e-76 256.8 5.3 1.7e-76 256.3 3.7 1.2 1 0 0 1 1 1 1 Pectate lyase MFS_1 PF07690.11 KFY03801.1 - 2.7e-36 125.0 26.2 2.7e-36 125.0 18.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Arylsulfotran_2 PF14269.1 KFY03802.1 - 1.7e-21 76.6 0.0 2.8e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 KFY03802.1 - 6.4e-21 74.4 0.0 7.3e-10 37.9 0.0 3.0 1 1 1 2 2 2 2 Arylsulfotransferase (ASST) PQQ_2 PF13360.1 KFY03802.1 - 1.1e-05 25.0 0.0 0.00015 21.3 0.0 2.2 2 1 0 2 2 2 1 PQQ-like domain Transferase PF02458.10 KFY03803.1 - 7.4e-09 34.5 0.0 1.2e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Transferase family UBX PF00789.15 KFY03804.1 - 0.082 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 UBX domain TACC PF05010.9 KFY03805.1 - 0.0022 17.7 4.4 0.04 13.6 0.1 2.4 2 0 0 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC) RPA_interact_M PF14767.1 KFY03805.1 - 0.83 10.4 0.1 0.83 10.4 0.0 3.3 3 0 0 3 3 3 0 Replication protein A interacting middle DUF4407 PF14362.1 KFY03805.1 - 1.8 7.4 7.7 0.88 8.4 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ERM PF00769.14 KFY03805.1 - 3.3 7.1 15.7 5.9 6.3 2.4 2.3 2 0 0 2 2 2 0 Ezrin/radixin/moesin family V-ATPase_G PF03179.10 KFY03805.1 - 9 6.6 9.8 1.2 9.4 0.7 2.4 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit PQ-loop PF04193.9 KFY03806.1 - 1.9e-06 27.3 0.8 4.3e-06 26.1 0.5 1.7 1 1 0 1 1 1 1 PQ loop repeat Herpes_glycop PF01528.11 KFY03806.1 - 0.17 10.5 1.3 0.15 10.7 0.5 1.2 1 1 0 1 1 1 0 Herpesvirus glycoprotein M GATase_5 PF13507.1 KFY03807.1 - 7.4e-98 326.5 0.0 1.2e-97 325.8 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 KFY03807.1 - 2.2e-44 151.1 3.2 1.6e-22 80.1 0.0 3.5 4 0 0 4 4 4 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 KFY03807.1 - 6.5e-25 87.2 2.9 5.5e-23 81.0 0.0 3.7 4 0 0 4 4 4 1 AIR synthase related protein, N-terminal domain TPR_11 PF13414.1 KFY03808.1 - 5.8e-35 118.7 5.5 6e-09 35.4 0.0 7.5 6 1 1 7 7 7 7 TPR repeat TPR_2 PF07719.12 KFY03808.1 - 1.5e-33 112.0 1.1 2.2e-05 23.9 0.0 10.5 10 0 0 10 10 10 7 Tetratricopeptide repeat Apc3 PF12895.2 KFY03808.1 - 1.7e-31 108.1 5.8 7.3e-23 80.5 0.1 5.7 4 2 3 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KFY03808.1 - 9.7e-29 97.7 0.0 9.5e-06 25.0 0.0 9.5 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 KFY03808.1 - 2.6e-25 88.1 5.0 3e-10 39.8 0.0 8.6 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.1 KFY03808.1 - 3e-24 85.1 1.7 0.0033 17.7 0.0 8.8 6 3 2 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 KFY03808.1 - 5.3e-21 72.7 0.0 1.9e-05 24.0 0.0 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 KFY03808.1 - 3.4e-20 72.1 0.4 1.7e-05 25.3 0.0 7.3 6 3 3 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 KFY03808.1 - 1.9e-18 65.2 3.2 0.00022 21.5 0.0 9.7 5 3 5 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.1 KFY03808.1 - 2.2e-17 61.3 1.8 2.2e-05 23.9 0.0 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 KFY03808.1 - 6.9e-15 54.4 0.6 1.1e-05 25.1 0.0 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFY03808.1 - 1.3e-13 50.4 3.3 0.02 15.3 0.0 7.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_4 PF07721.9 KFY03808.1 - 2.8e-09 36.5 0.3 0.0075 16.5 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 KFY03808.1 - 1.4e-08 34.2 0.1 4.1 7.8 0.0 8.0 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 KFY03808.1 - 3.9e-08 33.0 0.5 0.0083 15.9 0.0 5.5 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 KFY03808.1 - 0.00017 20.7 0.1 3 6.8 0.0 5.3 3 2 3 7 7 7 1 Tetratricopeptide repeat PPR PF01535.15 KFY03808.1 - 0.00048 19.9 4.9 0.071 13.1 0.1 4.4 4 0 0 4 4 4 1 PPR repeat DUF3856 PF12968.2 KFY03808.1 - 0.0018 18.0 0.6 0.12 12.1 0.0 3.1 3 0 0 3 3 3 1 Domain of Unknown Function (DUF3856) RPN7 PF10602.4 KFY03808.1 - 0.0025 17.1 0.6 0.59 9.4 0.0 4.0 3 2 0 4 4 4 1 26S proteasome subunit RPN7 MIT PF04212.13 KFY03808.1 - 0.16 11.8 1.3 23 4.9 0.0 3.9 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_21 PF09976.4 KFY03808.1 - 0.68 9.8 10.2 3.1 7.7 0.0 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat Ribosomal_L27 PF01016.14 KFY03809.1 - 1.2e-29 101.8 0.1 2.5e-29 100.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal L27 protein tRNA-synt_1c PF00749.16 KFY03811.1 - 1.3e-101 339.3 0.1 1.7e-101 339.0 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KFY03811.1 - 1.9e-39 135.1 0.1 3.3e-39 134.3 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.14 KFY03811.1 - 0.016 14.3 0.5 0.045 12.8 0.2 1.6 1 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Ribosomal_L1 PF00687.16 KFY03812.1 - 1.1e-31 109.8 0.0 1.6e-31 109.4 0.0 1.2 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Phage_tail_S PF05069.8 KFY03812.1 - 0.093 12.5 2.3 0.17 11.6 1.6 1.4 1 0 0 1 1 1 0 Phage virion morphogenesis family COG2 PF06148.6 KFY03813.1 - 7.8e-29 100.2 0.8 1.3e-28 99.5 0.5 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 KFY03813.1 - 2.3e-05 24.1 0.8 0.00058 19.6 0.0 2.5 2 0 0 2 2 2 1 Vps51/Vps67 Spc7 PF08317.6 KFY03813.1 - 0.00077 18.2 0.5 0.0012 17.6 0.4 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3287 PF11690.3 KFY03813.1 - 0.062 13.3 0.0 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) AlkA_N PF06029.6 KFY03813.1 - 0.073 13.1 1.3 0.36 10.9 0.0 2.5 3 0 0 3 3 3 0 AlkA N-terminal domain IncA PF04156.9 KFY03813.1 - 0.25 10.8 6.2 15 5.1 4.4 2.2 1 1 0 1 1 1 0 IncA protein Hap4_Hap_bind PF10297.4 KFY03814.1 - 3e-06 26.8 9.8 3e-06 26.8 6.8 3.4 3 0 0 3 3 3 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 ERM PF00769.14 KFY03814.1 - 2e-05 24.2 6.8 3.2e-05 23.5 4.7 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family bZIP_1 PF00170.16 KFY03814.1 - 9.6e-05 22.2 12.8 9.6e-05 22.2 8.9 2.5 2 1 2 4 4 4 1 bZIP transcription factor Atg14 PF10186.4 KFY03814.1 - 0.00011 21.2 1.1 0.00018 20.5 0.8 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 RRN3 PF05327.6 KFY03814.1 - 0.19 9.7 0.1 0.26 9.3 0.1 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Herpes_UL25 PF01499.11 KFY03814.1 - 6.5 4.9 7.4 10 4.3 5.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family Acyl-CoA_dh_2 PF08028.6 KFY03814.1 - 7.4 6.8 8.0 15 5.8 5.6 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain TPR_11 PF13414.1 KFY03815.1 - 2.2e-09 36.7 0.0 9.6e-09 34.7 0.0 2.1 1 0 0 1 1 1 1 TPR repeat UBA PF00627.26 KFY03815.1 - 0.00024 20.8 0.0 0.0005 19.8 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain TPR_2 PF07719.12 KFY03815.1 - 0.0006 19.5 0.1 0.68 10.0 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat DnaJ PF00226.26 KFY03815.1 - 0.0077 15.9 0.0 0.028 14.1 0.0 2.0 1 0 0 1 1 1 1 DnaJ domain TPR_12 PF13424.1 KFY03815.1 - 0.057 13.3 0.1 0.63 10.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFY03815.1 - 0.11 12.1 0.0 2.1 8.0 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Adenylate_cycl PF01295.13 KFY03815.1 - 1.8 6.7 3.4 1.1 7.4 0.9 1.5 2 0 0 2 2 2 0 Adenylate cyclase, class-I PhoD PF09423.5 KFY03816.1 - 1.6e-51 175.3 0.0 2.4e-51 174.7 0.0 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase SGS PF05002.10 KFY03816.1 - 9.2e-31 105.4 0.7 2e-30 104.3 0.5 1.6 1 0 0 1 1 1 1 SGS domain CS PF04969.11 KFY03816.1 - 4.1e-18 65.6 0.1 8e-18 64.7 0.1 1.5 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 KFY03816.1 - 5.1e-07 29.2 2.6 1e-06 28.2 1.0 2.1 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 KFY03816.1 - 0.0029 17.4 4.8 3.1 7.9 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFY03816.1 - 0.011 15.3 3.7 1.8 8.3 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFY03816.1 - 0.019 15.2 0.3 0.89 9.9 0.1 2.7 1 1 0 2 2 2 0 Tetratricopeptide repeat CtaG_Cox11 PF04442.9 KFY03816.1 - 0.039 13.7 0.2 0.069 12.9 0.2 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein CtaG/Cox11 TPR_16 PF13432.1 KFY03816.1 - 0.094 13.4 6.0 0.44 11.2 2.0 3.2 2 1 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 KFY03817.1 - 3e-70 236.3 0.0 4.6e-70 235.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY03817.1 - 2.4e-46 157.9 0.0 5.6e-46 156.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFY03817.1 - 1.4e-05 24.2 0.0 6.4e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like hNIFK_binding PF12196.3 KFY03817.1 - 0.16 11.3 1.3 0.43 10.0 0.9 1.8 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK YABBY PF04690.8 KFY03817.1 - 0.29 11.3 2.4 0.19 11.9 0.2 1.8 2 0 0 2 2 2 0 YABBY protein Transglut_core PF01841.14 KFY03818.1 - 2.2e-12 47.1 0.1 7.1e-12 45.5 0.1 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.12 KFY03818.1 - 3.6e-09 35.9 0.2 1.7e-08 33.7 0.1 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KFY03818.1 - 3e-06 26.5 0.0 1.3e-05 24.4 0.0 2.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFY03818.1 - 7e-05 22.3 0.0 0.0002 20.8 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain Transglut_core2 PF13369.1 KFY03818.1 - 0.14 11.6 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily SnoaL_4 PF13577.1 KFY03819.1 - 1.1e-22 80.2 0.0 1.3e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.2 KFY03819.1 - 0.00032 21.2 0.2 0.00073 20.0 0.1 1.6 1 1 0 1 1 1 1 Putative lumazine-binding SnoaL_3 PF13474.1 KFY03819.1 - 0.0073 16.3 0.0 0.014 15.4 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 KFY03819.1 - 0.012 15.8 0.0 0.017 15.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Scytalone_dh PF02982.9 KFY03819.1 - 0.039 13.5 0.1 0.086 12.4 0.1 1.6 1 1 0 1 1 1 0 Scytalone dehydratase SnoaL_2 PF12680.2 KFY03819.1 - 0.05 14.0 0.1 0.071 13.5 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain MTHFR PF02219.12 KFY03820.1 - 1e-110 369.3 0.0 1.4e-110 368.8 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase NOGCT PF08155.6 KFY03822.1 - 1.5e-29 101.4 2.8 5.9e-29 99.5 1.9 2.0 2 0 0 2 2 2 1 NOGCT (NUC087) domain NOG1 PF06858.9 KFY03822.1 - 6.7e-27 93.1 0.7 1.6e-26 91.9 0.5 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 KFY03822.1 - 1.2e-14 54.2 0.0 2.5e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KFY03822.1 - 4.1e-08 32.6 0.0 1e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KFY03822.1 - 0.00024 21.5 0.0 0.002 18.5 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein AAA_16 PF13191.1 KFY03822.1 - 0.027 14.4 0.2 1.5 8.7 0.1 3.2 2 1 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.18 KFY03822.1 - 0.03 14.1 0.0 8.7 6.1 0.0 2.6 1 1 1 2 2 2 0 Dynamin family AAA_22 PF13401.1 KFY03822.1 - 0.11 12.6 0.1 3 7.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain Asp_protease PF09668.5 KFY03823.1 - 8e-63 209.5 0.2 1.2e-62 208.9 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 KFY03823.1 - 4.7e-12 46.2 0.0 9.4e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 KFY03823.1 - 3.4e-10 39.1 0.1 5.7e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KFY03823.1 - 2.8e-08 33.3 0.0 6.9e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain RVP_2 PF08284.6 KFY03823.1 - 2e-07 31.0 0.0 3.3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KFY03823.1 - 4.7e-06 26.3 0.0 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease UN_NPL4 PF11543.3 KFY03823.1 - 6.8e-05 23.0 0.0 0.00015 21.9 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 YukD PF08817.5 KFY03823.1 - 0.00012 22.5 0.3 0.00026 21.5 0.2 1.6 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD RVP PF00077.15 KFY03823.1 - 0.00013 21.8 0.1 0.00065 19.5 0.0 2.3 3 1 0 3 3 3 1 Retroviral aspartyl protease Rad60-SLD PF11976.3 KFY03823.1 - 0.00057 19.5 0.1 0.0018 17.9 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like RuvA_C PF07499.8 KFY03823.1 - 0.021 14.9 0.0 0.074 13.2 0.0 2.0 1 0 0 1 1 1 0 RuvA, C-terminal domain UBA_4 PF14555.1 KFY03823.1 - 0.039 13.4 1.3 0.076 12.5 0.2 2.0 2 0 0 2 2 2 0 UBA-like domain Methyltransf_8 PF05148.10 KFY03824.1 - 3.5e-55 187.0 0.1 4.2e-53 180.2 0.0 2.9 3 1 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 KFY03824.1 - 1.5e-07 31.8 0.1 6.3e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY03824.1 - 0.0037 16.8 0.1 2.7 7.5 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_32 PF13679.1 KFY03824.1 - 0.0037 16.9 0.1 0.014 15.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Fungal_trans_2 PF11951.3 KFY03825.1 - 5.9e-20 71.2 0.6 6.3e-13 48.0 0.6 3.2 3 0 0 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY03825.1 - 1.3e-07 31.3 10.7 2.3e-07 30.6 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.21 KFY03826.1 - 8.9e-57 191.4 0.0 1.1e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KFY03826.1 - 1.2e-13 50.1 0.0 2.2e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 KFY03826.1 - 0.0043 16.7 0.2 0.13 11.9 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3137) Spc97_Spc98 PF04130.8 KFY03827.1 - 3.3e-131 438.2 0.2 3.3e-131 438.2 0.2 1.7 2 0 0 2 2 2 1 Spc97 / Spc98 family YqeY PF09424.5 KFY03828.1 - 5.7e-18 65.1 8.9 6.5e-18 64.9 6.2 1.0 1 0 0 1 1 1 1 Yqey-like protein 4HBT_3 PF13622.1 KFY03833.1 - 1.7e-18 67.2 0.0 2.5e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KFY03833.1 - 3.7e-18 65.4 0.0 7.6e-11 41.7 0.0 2.1 2 0 0 2 2 2 2 Acyl-CoA thioesterase Oxysterol_BP PF01237.13 KFY03834.1 - 2e-129 431.1 0.4 6e-129 429.5 0.0 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein ATP12 PF07542.6 KFY03834.1 - 1.8e-35 121.5 0.1 4e-35 120.4 0.1 1.6 1 0 0 1 1 1 1 ATP12 chaperone protein Ank_2 PF12796.2 KFY03834.1 - 7.1e-18 64.7 0.1 1e-11 45.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFY03834.1 - 9.1e-18 63.8 3.7 8.2e-10 38.6 0.1 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 KFY03834.1 - 5.3e-17 60.6 0.4 1.8e-05 24.2 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KFY03834.1 - 1.1e-15 57.6 0.1 8.5e-09 35.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) GAT PF03127.9 KFY03834.1 - 4.8e-14 52.1 1.1 4.4e-13 49.0 0.2 2.6 2 0 0 2 2 2 1 GAT domain Ank_3 PF13606.1 KFY03834.1 - 8.8e-12 44.0 0.1 0.005 16.9 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat PH PF00169.24 KFY03834.1 - 1.7e-11 44.2 0.7 6.9e-11 42.2 0.4 2.2 2 0 0 2 2 2 1 PH domain PH_8 PF15409.1 KFY03834.1 - 4.7e-07 29.7 1.1 1.4e-06 28.2 0.5 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain DUF1886 PF09171.5 KFY03834.1 - 0.0091 15.0 0.1 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1886) UBA_4 PF14555.1 KFY03835.1 - 4.4e-11 42.1 0.3 9e-11 41.1 0.2 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 KFY03835.1 - 2.3e-09 37.1 0.0 5.1e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 UBX domain Phage_Mu_F PF04233.9 KFY03835.1 - 1.1 9.7 6.5 2.7 8.5 4.5 1.6 1 0 0 1 1 1 0 Phage Mu protein F like protein Macoilin PF09726.4 KFY03835.1 - 6.4 4.9 12.5 9.2 4.3 8.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Pkinase PF00069.20 KFY03836.1 - 0.00019 20.6 0.0 0.00035 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain MGC-24 PF05283.6 KFY03836.1 - 0.025 14.3 4.5 0.055 13.2 3.1 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) BCAS2 PF05700.6 KFY03837.1 - 0.01 15.3 2.2 0.012 15.1 1.5 1.1 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF3824 PF12868.2 KFY03837.1 - 0.12 13.3 1.1 0.14 13.0 0.2 1.5 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) Peptidase_M43 PF05572.8 KFY03845.1 - 1.7e-16 60.1 0.0 3e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Peptidase_M10 PF00413.19 KFY03845.1 - 0.00015 21.5 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Matrixin Reprolysin_2 PF13574.1 KFY03845.1 - 0.0014 18.7 0.2 0.003 17.6 0.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KFY03845.1 - 0.0035 16.9 0.4 0.0035 16.9 0.3 1.8 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KFY03845.1 - 0.004 17.1 0.4 0.0066 16.3 0.3 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 KFY03845.1 - 0.034 14.6 4.0 0.25 11.8 1.4 2.8 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Sugar_tr PF00083.19 KFY03848.1 - 4.2e-80 269.5 24.3 4.8e-80 269.3 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY03848.1 - 1.6e-20 73.1 30.5 1.6e-20 73.1 21.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFY03848.1 - 1.8e-06 26.6 33.2 6.9e-05 21.4 2.3 3.2 3 1 0 3 3 3 2 MFS/sugar transport protein Sulfatase PF00884.18 KFY03849.1 - 3.6e-67 226.7 0.1 4.8e-67 226.3 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 KFY03849.1 - 3.3e-10 39.8 3.7 2.6e-09 36.9 2.6 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 KFY03849.1 - 0.021 13.2 0.0 0.036 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) RepL PF05732.6 KFY03849.1 - 0.074 12.2 0.3 0.13 11.5 0.2 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) Glyco_hydro_20 PF00728.17 KFY03850.1 - 2.9e-80 270.0 0.0 3.9e-80 269.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 KFY03850.1 - 4.9e-24 85.4 0.0 1.2e-23 84.2 0.0 1.6 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KFY03850.1 - 9.5e-05 22.9 0.0 0.00066 20.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Corona_NS2A PF05213.7 KFY03850.1 - 0.073 12.3 0.0 0.17 11.1 0.0 1.5 2 0 0 2 2 2 0 Coronavirus NS2A protein ECH PF00378.15 KFY03851.1 - 1.5e-27 96.3 0.0 1.9e-27 95.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF3533 PF12051.3 KFY03852.1 - 2.8e-94 316.0 15.0 3.9e-94 315.5 10.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) T2SM_b PF10741.4 KFY03852.1 - 0.072 12.7 0.1 0.18 11.4 0.0 1.6 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b Isochorismatase PF00857.15 KFY03853.1 - 1.2e-43 149.0 0.0 1.3e-43 148.9 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF1694 PF07997.6 KFY03853.1 - 0.081 12.8 0.0 2.2 8.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1694) GFA PF04828.9 KFY03854.1 - 6.5e-20 70.8 0.0 8.7e-20 70.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 KFY03854.1 - 0.048 12.8 0.4 0.048 12.8 0.2 2.1 2 0 0 2 2 2 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 KFY03854.1 - 0.065 12.7 0.9 0.065 12.7 0.6 2.2 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain DZR PF12773.2 KFY03854.1 - 0.1 12.4 0.1 0.1 12.4 0.0 1.9 2 1 0 2 2 2 0 Double zinc ribbon NOB1_Zn_bind PF08772.6 KFY03854.1 - 0.11 12.3 1.2 0.12 12.2 0.1 1.6 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Nudix_N_2 PF14803.1 KFY03854.1 - 0.14 11.8 0.1 0.14 11.8 0.1 2.1 3 0 0 3 3 3 0 Nudix N-terminal DUF1936 PF09151.5 KFY03854.1 - 0.23 11.0 0.0 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1936) Lar_restr_allev PF14354.1 KFY03854.1 - 1.4 9.2 5.5 11 6.3 0.2 2.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar NmrA PF05368.8 KFY03856.1 - 8.5e-33 113.5 0.0 2.8e-32 111.8 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFY03856.1 - 3.1e-08 33.8 0.3 4.7e-08 33.2 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 KFY03856.1 - 5.2e-05 23.2 0.1 8.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 KFY03856.1 - 0.0012 17.5 0.0 0.0016 17.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 KFY03856.1 - 0.056 13.8 0.1 0.12 12.8 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 KFY03856.1 - 0.071 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Zn_clus PF00172.13 KFY03857.1 - 9.5e-07 28.6 12.3 1.7e-06 27.8 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF377 PF04041.8 KFY03858.1 - 6.7e-56 189.2 0.0 9.1e-56 188.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF377) Glyco_hydro_43 PF04616.9 KFY03858.1 - 8.4e-11 41.4 2.2 4.1e-05 22.8 0.0 4.0 3 1 1 4 4 4 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KFY03858.1 - 1.2e-09 37.9 4.4 2.4e-08 33.6 0.1 2.8 3 0 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain DUF377 PF04041.8 KFY03859.1 - 1.5e-51 175.0 0.0 1.8e-51 174.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF377) Glyco_hydro_43 PF04616.9 KFY03859.1 - 7.8e-09 35.0 0.5 1e-05 24.8 0.1 3.9 3 1 0 4 4 4 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 KFY03859.1 - 1.5e-08 34.4 0.9 3.5e-06 26.6 0.0 2.8 2 1 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain Sugar_tr PF00083.19 KFY03860.1 - 2.9e-74 250.2 19.3 3.3e-74 250.0 13.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY03860.1 - 1.3e-35 122.8 44.6 2e-27 95.8 18.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4293 PF14126.1 KFY03860.1 - 0.045 13.6 2.5 0.38 10.6 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Glyco_hydro_2 PF00703.16 KFY03861.1 - 1.1e-10 41.9 0.0 2.2e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KFY03861.1 - 2.8e-05 23.7 0.0 5.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Zn_clus PF00172.13 KFY03862.1 - 0.00012 21.9 7.8 0.00021 21.1 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.11 KFY03863.1 - 7e-18 65.2 1.0 4.1e-15 56.1 0.0 2.1 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family TilS PF09179.6 KFY03863.1 - 0.34 10.9 2.1 0.55 10.2 0.4 2.1 2 0 0 2 2 2 0 TilS substrate binding domain PNK3P PF08645.6 KFY03864.1 - 4e-26 91.3 0.0 9.8e-26 90.0 0.0 1.6 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 KFY03864.1 - 1.2e-12 47.9 0.0 3.7e-11 43.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KFY03864.1 - 0.0055 17.5 0.0 0.013 16.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KFY03864.1 - 0.0059 15.7 0.0 0.0099 14.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 KFY03864.1 - 0.038 14.1 0.0 0.1 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KFY03864.1 - 0.091 12.9 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 KFY03864.1 - 0.16 11.1 0.0 0.47 9.6 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Dynein_light PF01221.13 KFY03876.1 - 1.6e-41 140.1 1.7 2e-41 139.8 1.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Imm28 PF15574.1 KFY03876.1 - 0.036 13.6 0.1 0.059 12.9 0.1 1.3 1 1 0 1 1 1 0 Immunity protein 28 RRM_1 PF00076.17 KFY03877.1 - 2.7e-75 247.9 1.0 1.1e-17 63.3 0.0 5.7 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY03877.1 - 1.1e-63 211.1 0.4 3e-13 49.5 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFY03877.1 - 1.3e-36 124.1 0.0 4.7e-09 35.9 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KFY03877.1 - 1.6e-06 27.7 1.1 0.17 11.6 0.0 4.9 5 1 0 5 5 5 2 Limkain b1 Nup35_RRM_2 PF14605.1 KFY03877.1 - 3.5e-06 26.6 0.0 0.8 9.5 0.0 3.6 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KFY03877.1 - 0.00023 20.9 2.2 3.4 7.5 0.0 4.1 3 1 0 3 3 3 2 RNA binding motif DUF1330 PF07045.6 KFY03877.1 - 0.23 11.3 3.1 1.3 8.8 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1330) Dicistro_VP4 PF11492.3 KFY03877.1 - 0.44 10.5 2.9 3.4 7.7 0.4 2.7 2 0 0 2 2 2 0 Cricket paralysis virus, VP4 TEA PF01285.13 KFY03878.1 - 8.7e-20 71.2 1.0 8.7e-20 71.2 0.7 2.6 2 1 1 3 3 3 1 TEA/ATTS domain family NAD_binding_1 PF00175.16 KFY03879.1 - 3.1e-28 98.4 0.0 5.9e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KFY03879.1 - 3.1e-21 75.3 0.0 5.5e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KFY03879.1 - 1.1e-09 38.4 0.0 4.9e-05 23.2 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KFY03879.1 - 0.00023 21.1 0.0 0.00058 19.8 0.0 1.7 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain DUF4366 PF14283.1 KFY03879.1 - 0.07 12.5 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Fungal_trans PF04082.13 KFY03880.1 - 9.9e-13 47.5 0.0 1.5e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY03880.1 - 1.2e-09 37.8 11.1 2.1e-09 37.1 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YpM PF09144.5 KFY03880.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Yersinia pseudotuberculosis mitogen Dickkopf_N PF04706.7 KFY03880.1 - 8.5 6.6 13.4 39 4.5 9.3 2.0 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region DUF3395 PF11875.3 KFY03881.1 - 7.3e-26 90.6 0.0 1.5e-25 89.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 KFY03881.1 - 3.4e-15 55.5 0.6 8.5e-15 54.2 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain Tom22 PF04281.8 KFY03881.1 - 0.37 10.3 4.7 5.5 6.5 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Nucleoplasmin PF03066.10 KFY03881.1 - 2.2 7.7 7.7 5 6.6 5.4 1.5 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 KFY03881.1 - 2.9 8.1 10.1 9.6 6.5 6.4 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Dicty_REP PF05086.7 KFY03881.1 - 4 5.0 5.7 5.5 4.6 3.9 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein FRG1 PF06229.7 KFY03882.1 - 2.2e-56 190.3 0.1 3.1e-56 189.8 0.1 1.2 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 KFY03882.1 - 0.06 13.4 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Fascin domain 2OG-FeII_Oxy PF03171.15 KFY03883.1 - 0.025 14.8 0.0 0.075 13.3 0.0 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Daxx PF03344.10 KFY03884.1 - 0.096 11.1 1.3 0.13 10.7 0.9 1.1 1 0 0 1 1 1 0 Daxx Family DUF1656 PF07869.7 KFY03884.1 - 0.23 11.2 1.3 0.5 10.1 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) DUF1100 PF06500.6 KFY03885.1 - 5.5e-10 38.3 0.0 1.3e-09 37.1 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_5 PF12695.2 KFY03885.1 - 6.6e-10 38.9 0.0 2.5e-09 37.0 0.0 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFY03885.1 - 2e-07 31.1 0.3 1e-06 28.8 0.1 2.2 1 1 2 3 3 3 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFY03885.1 - 4.3e-06 26.1 0.0 1.4e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 KFY03885.1 - 0.00057 19.3 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Putative esterase PAF-AH_p_II PF03403.8 KFY03885.1 - 0.16 10.1 0.0 0.45 8.7 0.0 1.6 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II ChW PF07538.6 KFY03885.1 - 0.37 10.3 1.9 0.81 9.2 1.3 1.5 1 0 0 1 1 1 0 Clostridial hydrophobic W ADH_zinc_N PF00107.21 KFY03886.1 - 7.9e-12 44.8 0.0 2e-11 43.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KFY03886.1 - 3.7e-05 23.4 0.1 0.0018 17.9 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.11 KFY03888.1 - 2.1e-31 108.9 24.4 7.9e-25 87.3 6.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KFY03888.1 - 0.035 14.1 5.0 3.2 7.8 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) DUF3792 PF12670.2 KFY03888.1 - 6.6 6.6 12.3 0.78 9.6 1.4 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3792) Abhydrolase_3 PF07859.8 KFY03889.1 - 8.5e-49 165.9 0.0 1.2e-48 165.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KFY03889.1 - 7.6e-05 21.6 0.1 0.00017 20.4 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 KFY03889.1 - 0.0054 16.6 1.1 0.0084 16.0 0.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PsbU PF06514.6 KFY03889.1 - 0.12 12.2 0.1 0.46 10.3 0.0 1.9 2 0 0 2 2 2 0 Photosystem II 12 kDa extrinsic protein (PsbU) FMO-like PF00743.14 KFY03890.1 - 4.7e-41 140.5 0.0 8e-21 73.8 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFY03890.1 - 2.1e-15 57.3 1.1 5.1e-14 52.8 0.5 2.8 2 2 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFY03890.1 - 2.3e-09 37.4 0.0 0.00078 19.3 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFY03890.1 - 6.3e-09 35.7 0.6 1.9e-06 27.7 1.0 3.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 KFY03890.1 - 9.7e-09 34.7 0.3 2.6e-06 26.7 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 KFY03890.1 - 1.4e-08 34.0 3.0 0.024 13.5 1.5 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFY03890.1 - 3.2e-08 33.8 0.7 0.00041 20.6 0.2 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFY03890.1 - 4.5e-07 29.8 0.0 2.1e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KFY03890.1 - 1.1e-05 24.5 1.6 4.2e-05 22.6 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KFY03890.1 - 7.7e-05 21.8 0.7 0.00015 20.9 0.5 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KFY03890.1 - 0.006 15.1 1.0 0.006 15.1 0.7 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 KFY03890.1 - 0.016 14.2 1.9 0.022 13.8 0.6 1.7 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.2 KFY03890.1 - 0.024 13.6 0.1 0.11 11.5 0.0 2.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 KFY03890.1 - 0.062 12.4 0.0 7 5.7 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 KFY03890.1 - 0.078 12.8 0.3 0.58 9.9 0.0 2.3 3 0 0 3 3 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Metallophos_2 PF12850.2 KFY03890.1 - 0.1 12.3 0.0 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain Shikimate_DH PF01488.15 KFY03890.1 - 0.16 12.0 0.3 16 5.6 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 KFY03890.1 - 0.16 11.2 0.3 0.32 10.3 0.2 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain FAD_binding_2 PF00890.19 KFY03890.1 - 0.17 10.7 1.1 0.35 9.6 0.8 1.5 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 KFY03890.1 - 0.21 11.1 1.6 0.24 11.0 0.3 1.6 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KFY03890.1 - 0.29 10.5 1.9 13 5.1 0.5 2.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.16 KFY03890.1 - 0.37 10.3 2.0 19 4.7 0.3 3.0 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain p450 PF00067.17 KFY03891.1 - 1.1e-62 212.0 0.0 1.5e-62 211.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AdoMet_MTase PF07757.8 KFY03901.1 - 0.00014 21.9 0.0 0.00017 21.6 0.0 1.1 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.1 KFY03901.1 - 0.0072 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFY03901.1 - 0.037 13.7 0.1 0.17 11.6 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 KFY03901.1 - 0.095 13.2 0.0 0.17 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 KFY03901.1 - 0.096 12.0 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW HEAT PF02985.17 KFY03902.1 - 7.9e-42 137.5 20.9 0.0015 18.4 0.1 13.2 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.1 KFY03902.1 - 4.8e-32 110.1 4.2 3.9e-09 36.6 0.0 7.8 2 2 6 8 8 8 7 HEAT repeats Vac14_Fab1_bd PF12755.2 KFY03902.1 - 1.6e-12 47.6 3.6 0.0045 17.3 0.1 7.6 4 2 3 8 8 8 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 KFY03902.1 - 9.1e-11 41.9 10.0 0.082 13.4 0.1 8.9 7 2 3 10 10 10 2 HEAT-like repeat Adaptin_N PF01602.15 KFY03902.1 - 2e-08 33.0 6.5 5.9e-05 21.5 1.5 3.7 2 1 1 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.3 KFY03902.1 - 6.5e-05 22.3 3.8 2.7 7.2 0.0 4.6 2 2 1 4 4 4 3 CLASP N terminal DUF2435 PF10363.4 KFY03902.1 - 0.0015 18.3 4.3 1.7 8.5 0.1 4.7 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) Cnd3 PF12719.2 KFY03902.1 - 0.018 14.0 1.4 0.14 11.1 0.2 2.6 2 1 1 3 3 3 0 Nuclear condensing complex subunits, C-term domain Arm PF00514.18 KFY03902.1 - 0.054 13.3 4.4 2.4 8.1 0.0 4.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat MadL PF03817.8 KFY03902.1 - 0.07 12.9 0.1 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Malonate transporter MadL subunit Cnd1 PF12717.2 KFY03902.1 - 0.24 11.2 10.1 12 5.6 0.2 6.2 3 1 2 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 KFY03902.1 - 0.24 9.6 4.5 0.64 8.2 0.1 2.7 2 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit Imm25 PF15571.1 KFY03902.1 - 0.25 11.4 3.4 1.3 9.1 0.0 3.4 3 1 1 4 4 4 0 Immunity protein 25 B3_4 PF03483.12 KFY03903.1 - 5.5e-26 91.0 0.0 9.2e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KFY03903.1 - 4.6e-18 64.8 0.0 8.8e-14 51.0 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain Herpes_V23 PF01802.12 KFY03903.1 - 0.0096 14.9 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 Herpesvirus VP23 like capsid protein Myotub-related PF06602.9 KFY03904.1 - 8e-125 416.2 0.0 1.1e-124 415.8 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DUF2531 PF10748.4 KFY03904.1 - 0.01 15.0 0.1 0.026 13.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2531) Y_phosphatase3 PF13350.1 KFY03904.1 - 0.034 14.3 0.0 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family Ribosomal_S3_C PF00189.15 KFY03905.1 - 1.2e-16 60.6 0.1 2.6e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 KFY03905.1 - 2.6e-12 46.1 0.1 4.7e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 KFY03905.1 - 0.059 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Mg_trans_NIPA PF05653.9 KFY03906.1 - 3.6e-112 374.2 14.0 4.2e-112 374.0 9.7 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KFY03906.1 - 1.3e-06 28.5 5.8 1.3e-06 28.5 4.0 3.5 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 KFY03906.1 - 0.00035 20.6 6.7 0.00035 20.6 4.6 3.2 2 2 0 2 2 2 1 EamA-like transporter family DUF2420 PF10336.4 KFY03907.1 - 2.9e-11 42.9 0.0 5.1e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.16 KFY03908.1 - 2e-18 66.4 0.5 2.9e-18 65.9 0.4 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KFY03908.1 - 1.5e-08 34.4 0.1 2.8e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.6 KFY03908.1 - 0.0092 16.1 0.1 0.024 14.7 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) DUF4654 PF15547.1 KFY03908.1 - 0.47 10.7 2.5 0.94 9.8 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4654) Apc4 PF12896.2 KFY03909.1 - 3.8e-48 163.5 0.0 5.9e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 KFY03909.1 - 3.7e-13 48.7 0.0 5.7e-12 44.9 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 KFY03909.1 - 6.3e-06 25.8 0.0 0.32 10.9 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat IKI3 PF04762.7 KFY03909.1 - 0.094 10.5 0.0 0.15 9.8 0.0 1.2 1 0 0 1 1 1 0 IKI3 family TRP PF06011.7 KFY03917.1 - 4.3e-157 523.1 31.0 4.3e-157 523.1 21.5 1.3 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KFY03917.1 - 1.8e-38 131.7 0.8 3.7e-38 130.7 0.5 1.5 1 0 0 1 1 1 1 ML-like domain gpUL132 PF11359.3 KFY03917.1 - 0.007 15.7 0.0 0.019 14.3 0.0 1.7 2 0 0 2 2 2 1 Glycoprotein UL132 DUF1049 PF06305.6 KFY03917.1 - 0.17 11.3 0.1 0.17 11.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) DUF843 PF05814.6 KFY03917.1 - 0.44 10.3 6.3 1.2 8.9 0.4 3.2 3 1 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) DUF1162 PF06650.7 KFY03919.1 - 5.9e-90 301.2 0.0 9.6e-88 293.9 0.0 2.9 2 1 1 3 3 3 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 KFY03919.1 - 6e-42 141.9 0.0 1.6e-41 140.5 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter DUF3429 PF11911.3 KFY03921.1 - 5e-39 133.5 7.0 6.7e-39 133.1 4.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) DUF1510 PF07423.6 KFY03921.1 - 0.00034 20.0 4.4 0.00055 19.3 3.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Methyltransf_23 PF13489.1 KFY03926.1 - 4.8e-15 55.6 0.0 8.3e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY03926.1 - 4.6e-09 36.6 0.0 8.7e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY03926.1 - 6.2e-09 35.6 0.0 5.4e-08 32.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY03926.1 - 6e-05 23.4 0.0 0.00018 21.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY03926.1 - 8.2e-05 23.1 0.2 0.00073 20.0 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFY03926.1 - 0.0019 17.3 0.0 0.0093 15.1 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family GidB PF02527.10 KFY03926.1 - 0.039 13.0 0.0 0.52 9.4 0.0 2.2 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Methyltransf_25 PF13649.1 KFY03926.1 - 0.069 13.5 0.0 0.2 12.0 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain CP2 PF04516.10 KFY03934.1 - 5.1e-71 238.4 0.0 7.4e-71 237.9 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Fungal_trans PF04082.13 KFY03936.1 - 1.2e-10 40.7 0.4 1.7e-10 40.2 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY03937.1 - 2.1e-09 37.1 12.7 3.8e-09 36.2 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFY03937.1 - 1.5e-08 33.8 0.0 2.9e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pneumo_phosprot PF02478.11 KFY03938.1 - 0.072 12.6 0.1 0.1 12.1 0.1 1.1 1 0 0 1 1 1 0 Pneumovirus phosphoprotein Longin PF13774.1 KFY03943.1 - 1.5e-25 88.5 0.3 2.6e-25 87.7 0.2 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KFY03943.1 - 7.9e-16 57.4 0.0 1.8e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Synaptobrevin DUF760 PF05542.6 KFY03943.1 - 0.062 13.4 0.1 0.61 10.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF760) DUF1664 PF07889.7 KFY03943.1 - 0.089 12.5 0.4 0.28 10.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) E1-E2_ATPase PF00122.15 KFY03943.1 - 0.4 9.6 1.5 12 4.9 0.1 2.8 2 1 1 3 3 3 0 E1-E2 ATPase Sirohm_synth_C PF14823.1 KFY03943.1 - 0.41 9.9 2.5 2.6 7.4 0.5 2.7 2 1 1 3 3 3 0 Sirohaem biosynthesis protein C-terminal ASXH PF13919.1 KFY03944.1 - 9.4e-27 93.4 0.5 1.6e-26 92.7 0.3 1.3 1 0 0 1 1 1 1 Asx homology domain Glyco_hydro_63 PF03200.11 KFY03945.1 - 1e-244 814.1 0.0 8.1e-244 811.1 0.0 1.8 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase GDE_C PF06202.9 KFY03945.1 - 0.00091 18.0 0.0 0.0016 17.2 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.13 KFY03945.1 - 0.0016 17.1 0.2 0.004 15.8 0.1 1.6 1 1 0 1 1 1 1 Trehalase DUF1777 PF08648.7 KFY03946.1 - 1.9e-22 79.8 48.4 1.9e-22 79.8 33.5 3.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) Elong_Iki1 PF10483.4 KFY03947.1 - 1.2e-84 284.0 0.0 1.4e-84 283.8 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Mso1_Sec1_bdg PF14475.1 KFY03948.1 - 4.1e-19 67.6 0.0 8.4e-19 66.6 0.0 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.12 KFY03949.1 - 3.1e-33 114.6 0.9 5.8e-33 113.7 0.6 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 KFY03949.1 - 1.3e-23 82.9 19.2 1.3e-23 82.9 13.3 3.0 2 1 0 2 2 2 1 Mak16 protein C-terminal region TFIIA PF03153.8 KFY03949.1 - 0.0017 18.3 7.5 0.002 18.1 5.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.5 KFY03949.1 - 0.065 12.3 25.6 0.094 11.7 17.5 1.4 1 1 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.7 KFY03949.1 - 0.98 7.7 22.6 1.1 7.5 15.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cut8_N PF14482.1 KFY03949.1 - 1 9.3 3.5 2.5 8.1 1.8 2.2 2 0 0 2 2 2 0 Cut8 proteasome-binding domain Nop14 PF04147.7 KFY03949.1 - 1.7 6.4 27.4 2.6 5.8 19.0 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 KFY03949.1 - 4.5 6.9 16.6 7.3 6.2 11.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Daxx PF03344.10 KFY03949.1 - 5.1 5.4 21.6 7 5.0 14.9 1.2 1 0 0 1 1 1 0 Daxx Family TrmE_N PF10396.4 KFY03950.1 - 5.2e-27 94.0 0.0 1.4e-26 92.6 0.0 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 KFY03950.1 - 4.1e-19 68.7 0.1 1.1e-18 67.3 0.1 1.8 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 KFY03950.1 - 3e-17 62.6 0.0 6.5e-17 61.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KFY03950.1 - 9.2e-06 25.5 0.0 1.9e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin family FeoB_N PF02421.13 KFY03950.1 - 0.00051 19.3 0.0 0.00086 18.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KFY03950.1 - 0.0026 18.2 0.0 0.008 16.6 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KFY03950.1 - 0.023 14.1 0.0 5 6.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KFY03950.1 - 0.08 13.2 0.0 0.22 11.7 0.0 1.8 2 0 0 2 2 2 0 ABC transporter DUF258 PF03193.11 KFY03950.1 - 0.1 11.7 0.0 0.26 10.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 zf-C2H2_4 PF13894.1 KFY03952.1 - 0.0086 16.3 0.0 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KFY03952.1 - 0.022 15.0 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Med6 PF04934.9 KFY03953.1 - 7.3e-44 148.7 0.0 1.7e-43 147.5 0.0 1.7 1 0 0 1 1 1 1 MED6 mediator sub complex component RabGAP-TBC PF00566.13 KFY03953.1 - 1.8e-37 128.9 0.3 3.5e-37 127.9 0.2 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MMtag PF10159.4 KFY03953.1 - 3.9e-28 97.3 4.4 1.2e-27 95.7 3.0 2.0 1 0 0 1 1 1 1 Kinase phosphorylation protein DUF3548 PF12068.3 KFY03953.1 - 2.2e-07 30.3 0.0 0.00014 21.2 0.0 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF3548) DUF3129 PF11327.3 KFY03954.1 - 8.3e-17 61.5 0.4 1.1e-16 61.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) F-box-like PF12937.2 KFY03955.1 - 7.3e-07 28.8 0.1 1.9e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like STAS PF01740.16 KFY03955.1 - 0.0001 21.7 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain F-box PF00646.28 KFY03955.1 - 0.011 15.4 0.3 0.028 14.0 0.0 1.9 2 0 0 2 2 2 0 F-box domain DUF3760 PF12586.3 KFY03955.1 - 0.047 13.5 0.2 0.095 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) Rifin_STEVOR PF02009.11 KFY03956.1 - 0.00037 20.2 0.0 0.00058 19.6 0.0 1.3 1 0 0 1 1 1 1 Rifin/stevor family MGC-24 PF05283.6 KFY03956.1 - 0.0013 18.5 9.0 0.0013 18.5 6.2 2.2 2 1 1 3 3 3 1 Multi-glycosylated core protein 24 (MGC-24) Podoplanin PF05808.6 KFY03956.1 - 0.0036 16.8 1.1 0.005 16.4 0.1 1.7 2 0 0 2 2 2 1 Podoplanin TMEM154 PF15102.1 KFY03956.1 - 0.0051 16.5 0.1 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 TMEM154 protein family Syndecan PF01034.15 KFY03956.1 - 0.066 12.8 1.0 0.15 11.7 0.7 1.5 1 0 0 1 1 1 0 Syndecan domain EphA2_TM PF14575.1 KFY03956.1 - 0.12 12.8 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Pox_A14 PF05767.7 KFY03956.1 - 0.13 12.2 0.1 0.35 10.8 0.1 1.6 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 MtrF PF09472.5 KFY03956.1 - 0.2 10.9 2.8 0.42 9.8 2.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF3070 PF11270.3 KFY03956.1 - 0.95 9.2 6.0 0.25 11.1 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3070) SKG6 PF08693.5 KFY03956.1 - 1.4 8.3 11.8 0.068 12.5 4.3 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain NDUF_B7 PF05676.8 KFY03957.1 - 6.7e-30 102.3 4.2 8.8e-30 101.9 2.9 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 KFY03957.1 - 0.04 13.6 2.6 0.054 13.2 1.8 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ank PF00023.25 KFY03958.1 - 1.5e-14 52.9 3.7 3.1e-06 26.7 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 KFY03958.1 - 1.1e-12 48.0 0.9 2e-05 24.8 0.0 3.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFY03958.1 - 9.9e-12 45.0 1.6 1.4e-05 25.4 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY03958.1 - 7.3e-10 38.7 0.7 0.0038 17.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.8 KFY03958.1 - 7.8e-08 31.9 0.0 2.3e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 KilA-N domain Ank_3 PF13606.1 KFY03958.1 - 6.7e-05 22.7 2.9 0.047 13.9 0.0 4.7 5 0 0 5 5 5 1 Ankyrin repeat MIS13 PF08202.6 KFY03959.1 - 4.7e-44 150.6 0.0 1.3e-43 149.2 0.0 1.7 2 0 0 2 2 2 1 Mis12-Mtw1 protein family WD40_alt PF14077.1 KFY03959.1 - 0.11 12.1 0.4 0.22 11.1 0.2 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif Nucleoporin_N PF08801.6 KFY03960.1 - 9.3e-46 156.4 0.0 1.1e-45 156.1 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Sedlin_N PF04628.8 KFY03961.1 - 3.5e-18 65.7 0.0 4.8e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Zn_clus PF00172.13 KFY03962.1 - 0.00054 19.8 21.9 0.085 12.7 5.3 3.8 2 1 1 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain TRAP_alpha PF03896.11 KFY03962.1 - 0.74 8.7 4.0 1.9 7.3 2.8 1.7 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF3328 PF11807.3 KFY03964.1 - 5.6e-14 52.3 0.0 1.6e-13 50.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) F-box-like PF12937.2 KFY03964.1 - 1.9 8.3 4.7 26 4.6 0.1 2.8 2 0 0 2 2 2 0 F-box-like Sugar_tr PF00083.19 KFY03966.1 - 1.2e-80 271.3 21.5 1.4e-80 271.0 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY03966.1 - 4.3e-31 107.9 25.9 4.7e-28 97.9 12.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFY03966.1 - 0.0012 17.1 4.4 0.0032 15.7 1.3 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2781 PF10914.3 KFY03966.1 - 0.058 13.1 0.1 0.058 13.1 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2781) Fungal_trans_2 PF11951.3 KFY03967.1 - 3.6e-22 78.4 0.2 7.3e-22 77.4 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.18 KFY03967.1 - 4.9e-17 61.6 0.3 1.2e-16 60.4 0.2 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFY03967.1 - 1.1e-06 28.3 1.4 2.9e-06 27.1 1.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cupin_2 PF07883.6 KFY03968.1 - 1.2e-10 40.7 0.0 2.3e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KFY03968.1 - 3.6e-06 26.4 0.0 4.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 KFY03968.1 - 2.3e-05 23.7 0.0 3.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) 3-HAO PF06052.7 KFY03968.1 - 6.4e-05 22.4 0.0 7.4e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_4 PF08007.7 KFY03968.1 - 0.0028 16.9 0.0 0.0036 16.6 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein ARD PF03079.9 KFY03968.1 - 0.019 14.9 0.0 0.027 14.4 0.0 1.3 1 1 0 1 1 1 0 ARD/ARD' family FdtA PF05523.6 KFY03968.1 - 0.019 14.4 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 WxcM-like, C-terminal HgmA PF04209.8 KFY03968.1 - 0.059 11.7 0.0 0.066 11.5 0.0 1.1 1 0 0 1 1 1 0 homogentisate 1,2-dioxygenase Cupin_6 PF12852.2 KFY03968.1 - 0.1 12.2 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Cupin GPI PF06560.6 KFY03968.1 - 0.1 11.5 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) AA_permease PF00324.16 KFY03969.1 - 1.7e-143 478.4 40.4 3e-104 349.0 20.2 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 KFY03969.1 - 4.3e-42 144.1 39.1 1.7e-31 109.2 20.6 2.0 2 0 0 2 2 2 2 Amino acid permease ClpS PF02617.12 KFY03969.1 - 0.15 11.8 0.0 18 5.1 0.0 2.3 2 0 0 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS MFS_1 PF07690.11 KFY03970.1 - 2.8e-38 131.5 24.2 2.8e-38 131.5 16.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily 2TM PF13239.1 KFY03970.1 - 2.3 8.3 12.4 3 7.9 2.3 3.7 3 0 0 3 3 3 0 2TM domain Mito_carr PF00153.22 KFY03978.1 - 4.7e-68 224.9 3.9 8.8e-22 76.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cofilin_ADF PF00241.15 KFY03979.1 - 4e-23 81.6 0.1 4.3e-13 49.2 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Med22 PF06179.7 KFY03980.1 - 1.9e-17 63.2 0.1 2.8e-17 62.6 0.1 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Pkinase PF00069.20 KFY03981.1 - 1e-57 195.2 0.0 4.1e-43 147.3 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFY03981.1 - 2.5e-28 98.8 0.0 5.8e-20 71.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KFY03981.1 - 5.7e-07 28.7 0.0 1.4e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Kinase-like TFIIA PF03153.8 KFY03981.1 - 2.1 8.1 13.9 3 7.6 9.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PseudoU_synth_1 PF01416.15 KFY03982.1 - 1.6e-21 76.6 0.0 4.1e-10 40.0 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase ESCRT-II PF05871.7 KFY03982.1 - 0.098 12.5 1.3 0.41 10.5 0.1 2.3 2 0 0 2 2 2 0 ESCRT-II complex subunit Peroxin-3 PF04882.7 KFY03982.1 - 1.3 7.6 4.7 0.47 9.1 1.5 1.5 2 0 0 2 2 2 0 Peroxin-3 TFIIE_alpha PF02002.12 KFY03983.1 - 6e-17 61.0 0.2 1.1e-16 60.2 0.1 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit SURF2 PF05477.6 KFY03983.1 - 0.19 10.8 2.9 0.32 10.0 2.0 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) ILVD_EDD PF00920.16 KFY03984.1 - 3.9e-205 682.2 1.1 4.5e-205 681.9 0.8 1.0 1 0 0 1 1 1 1 Dehydratase family Pkinase PF00069.20 KFY03985.1 - 5.1e-49 166.7 0.0 2.2e-47 161.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KFY03985.1 - 5.8e-28 97.6 0.0 2e-27 95.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFY03985.1 - 0.045 12.7 0.0 2.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Acyltransferase PF01553.16 KFY03986.1 - 0.14 11.6 0.0 0.51 9.7 0.0 1.9 1 1 0 1 1 1 0 Acyltransferase Kinesin PF00225.18 KFY03987.1 - 4.9e-106 354.2 1.0 4.9e-106 354.2 0.7 2.6 2 1 2 4 4 4 1 Kinesin motor domain WEMBL PF05701.6 KFY03987.1 - 0.00027 19.5 21.7 0.00027 19.5 15.1 2.5 2 1 1 3 3 3 2 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 KFY03987.1 - 0.28 10.3 13.1 0.25 10.4 2.2 3.1 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 KFY03987.1 - 4.7 7.0 10.7 0.35 10.6 1.4 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HAUS-augmin3 PF14932.1 KFY03988.1 - 9.4e-06 24.9 10.1 9.4e-06 24.9 7.0 3.3 3 0 0 3 3 3 2 HAUS augmin-like complex subunit 3 DUF1295 PF06966.7 KFY03991.1 - 7.2e-15 54.9 0.0 1e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 KFY03991.1 - 5.5e-06 25.1 0.1 8.6e-06 24.5 0.1 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 KFY03991.1 - 7e-05 22.8 0.5 0.00074 19.5 0.0 2.4 2 1 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.11 KFY03991.1 - 0.00026 20.7 0.0 0.00045 19.9 0.0 1.6 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase NnrU PF07298.6 KFY03991.1 - 0.00054 19.3 0.1 0.00081 18.8 0.1 1.2 1 0 0 1 1 1 1 NnrU protein ICMT PF04140.9 KFY03991.1 - 0.0032 17.6 0.0 0.0083 16.2 0.0 1.8 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family MFS_1 PF07690.11 KFY03992.1 - 2.7e-37 128.2 51.7 2.7e-37 128.2 35.9 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily EthD PF07110.6 KFY03993.1 - 2.1e-19 70.2 0.0 2.8e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 EthD domain ketoacyl-synt PF00109.21 KFY03994.1 - 3.2e-75 252.8 0.0 6.5e-75 251.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KFY03994.1 - 6.3e-46 157.1 0.0 4.1e-45 154.4 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KFY03994.1 - 9e-33 112.6 0.5 2.3e-32 111.3 0.3 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 KFY03994.1 - 6.9e-20 72.2 0.0 1.8e-19 70.8 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain PS-DH PF14765.1 KFY03994.1 - 2e-18 66.5 0.0 4.2e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase FAD_binding_3 PF01494.14 KFY03994.1 - 2.6e-16 59.6 1.0 3.6e-15 55.8 0.7 2.2 1 1 0 1 1 1 1 FAD binding domain PP-binding PF00550.20 KFY03994.1 - 1.5e-13 50.8 1.2 4.9e-13 49.1 0.8 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 KFY03994.1 - 1e-06 28.8 0.2 1.7e-05 24.8 0.0 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFY03994.1 - 2e-05 24.4 0.0 0.1 12.3 0.0 2.9 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 KFY03994.1 - 0.00042 19.3 0.0 0.00089 18.3 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain NAD_binding_8 PF13450.1 KFY03994.1 - 0.00051 20.0 0.0 0.0026 17.7 0.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KFY03994.1 - 0.0096 15.9 0.0 0.032 14.3 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KFY03994.1 - 0.081 11.7 0.0 0.97 8.2 0.0 2.3 2 0 0 2 2 2 0 Squalene epoxidase Lycopene_cycl PF05834.7 KFY03994.1 - 0.19 10.5 0.0 0.49 9.2 0.0 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein DUF2974 PF11187.3 KFY03994.1 - 0.23 10.7 0.0 0.49 9.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) LANC_like PF05147.8 KFY03995.1 - 2.4e-20 72.4 0.0 3.7e-19 68.5 0.0 2.0 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein FAD_binding_4 PF01565.18 KFY03996.1 - 3e-18 65.6 3.2 6.5e-18 64.5 2.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFY03996.1 - 9.3e-10 38.2 0.8 9.3e-10 38.2 0.6 2.0 2 0 0 2 2 2 1 Berberine and berberine like Acetyltransf_1 PF00583.19 KFY03997.1 - 3.9e-08 33.2 0.4 8.9e-08 32.0 0.3 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFY03997.1 - 4.1e-06 26.8 0.0 1.8e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFY03997.1 - 2.3e-05 24.4 0.3 7.8e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFY03997.1 - 0.0026 17.4 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KFY03997.1 - 0.0069 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.2 KFY03998.1 - 4.5e-28 98.6 2.9 6.4e-28 98.1 2.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFY03998.1 - 1e-10 41.5 0.0 1.8e-10 40.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY03998.1 - 0.00012 21.7 0.3 0.00094 18.7 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KFY03998.1 - 0.036 13.4 0.0 0.65 9.4 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 KFY03998.1 - 0.073 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Esterase PF00756.15 KFY03998.1 - 0.095 12.1 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF3089 PF11288.3 KFY03998.1 - 0.11 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Histone PF00125.19 KFY03999.1 - 3.7e-14 52.5 0.0 5.9e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KFY03999.1 - 0.0051 16.9 0.0 0.0083 16.2 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S DUF1409 PF07197.7 KFY04001.1 - 0.0066 16.4 1.8 0.0084 16.1 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1409) ACCA PF03255.9 KFY04001.1 - 0.014 14.9 0.4 0.026 14.0 0.3 1.4 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Ebola_NP PF05505.7 KFY04001.1 - 0.088 10.8 2.4 0.11 10.6 1.7 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein YscO PF07321.7 KFY04001.1 - 0.38 10.5 12.8 1.2 8.9 3.5 2.1 1 1 1 2 2 2 0 Type III secretion protein YscO Enkurin PF13864.1 KFY04001.1 - 0.73 10.0 11.5 2.1 8.6 7.5 2.0 1 1 1 2 2 2 0 Calmodulin-binding DUF349 PF03993.7 KFY04001.1 - 0.96 9.6 12.4 0.11 12.6 4.6 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) V_ATPase_I PF01496.14 KFY04001.1 - 3 5.5 4.3 3.9 5.2 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 KFY04001.1 - 3 6.7 7.9 4.7 6.0 5.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Sigma54_activ_2 PF14532.1 KFY04003.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Glyco_hydro_18 PF00704.23 KFY04011.1 - 3.7e-100 335.7 9.3 4.7e-100 335.3 6.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Na_H_Exchanger PF00999.16 KFY04013.1 - 1.4e-27 96.1 31.4 1.3e-25 89.7 13.4 2.5 3 0 0 3 3 3 2 Sodium/hydrogen exchanger family STE2 PF02116.10 KFY04014.1 - 4.1e-84 281.9 18.1 4.8e-84 281.7 12.5 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Vps23_core PF09454.5 KFY04017.1 - 2.6e-21 74.9 0.0 6.4e-21 73.7 0.0 1.6 2 0 0 2 2 2 1 Vps23 core domain zf-CHY PF05495.7 KFY04020.1 - 2.2e-17 62.9 14.9 2.2e-17 62.9 10.3 3.8 4 0 0 4 4 4 2 CHY zinc finger Mu-like_Com PF10122.4 KFY04020.1 - 0.0096 14.9 3.4 0.081 11.9 0.5 3.3 2 0 0 2 2 2 1 Mu-like prophage protein Com Cpn60_TCP1 PF00118.19 KFY04021.1 - 2.6e-147 491.3 2.7 2.9e-147 491.2 1.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ELFV_dehydrog PF00208.16 KFY04026.1 - 1.2e-86 290.3 2.5 1.4e-86 290.0 1.7 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 KFY04026.1 - 2.6e-46 156.4 0.0 1.4e-45 154.0 0.0 2.0 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 KFY04026.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding FMN_dh PF01070.13 KFY04027.1 - 1.4e-63 214.9 2.4 1.6e-63 214.7 1.6 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 KFY04027.1 - 2.4e-06 26.9 2.2 3.4e-06 26.4 1.5 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 KFY04027.1 - 5.3e-05 22.4 0.1 0.017 14.1 0.1 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KFY04027.1 - 0.00011 21.5 0.4 0.0081 15.4 0.1 2.1 1 1 1 2 2 2 2 Histidine biosynthesis protein Glu_synthase PF01645.12 KFY04027.1 - 0.00019 20.5 0.6 0.00033 19.6 0.4 1.6 1 1 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KFY04027.1 - 0.00019 20.4 0.4 0.00053 18.9 0.5 1.6 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain IGPS PF00218.16 KFY04027.1 - 0.002 17.2 0.3 0.0068 15.4 0.2 1.7 1 1 1 2 2 2 1 Indole-3-glycerol phosphate synthase DHO_dh PF01180.16 KFY04027.1 - 0.0058 15.6 0.2 0.026 13.4 0.1 1.9 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase DUF3040 PF11239.3 KFY04035.1 - 0.013 15.4 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) SET PF00856.23 KFY04036.1 - 3.8e-12 46.8 0.0 6.9e-11 42.7 0.0 2.5 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.1 KFY04036.1 - 4.3e-06 26.2 1.5 0.00035 20.1 0.0 3.1 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 KFY04036.1 - 0.00037 20.1 3.0 0.05 13.5 0.2 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KFY04036.1 - 0.00078 19.7 0.4 0.077 13.4 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KFY04036.1 - 0.043 14.4 2.9 8.8 7.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KFY04036.1 - 0.085 13.0 0.2 2.6 8.2 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 KFY04036.1 - 0.48 10.1 3.0 49 3.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_12 PF13087.1 KFY04037.1 - 1.8e-19 69.9 0.0 4.2e-19 68.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 KFY04037.1 - 2.2e-13 50.3 0.0 3.9e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 KFY04037.1 - 8.2e-06 25.5 0.0 0.025 14.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KFY04037.1 - 0.0029 17.3 0.0 0.01 15.5 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 KFY04037.1 - 0.012 15.1 0.0 7 6.0 0.0 3.5 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 KFY04037.1 - 0.03 13.7 0.0 0.11 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KFY04037.1 - 0.083 13.0 0.0 0.58 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KFY04037.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain HBS1_N PF08938.5 KFY04037.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 HBS1 N-terminus Zn_clus PF00172.13 KFY04038.1 - 5.3e-08 32.6 5.7 1.3e-07 31.3 3.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFY04038.1 - 0.0066 15.0 0.1 0.01 14.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C2 PF00648.16 KFY04046.1 - 2.6e-24 85.7 0.0 3.8e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.13 KFY04046.1 - 4.2e-06 26.5 3.9 7.1e-06 25.8 2.7 1.3 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain SAM_2 PF07647.12 KFY04047.1 - 4e-11 42.5 0.1 7.5e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KFY04047.1 - 3.5e-06 27.0 0.1 7.3e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.5 KFY04047.1 - 0.088 12.7 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 IGR protein motif TPR_11 PF13414.1 KFY04048.1 - 1.4e-19 69.4 33.3 5.9e-08 32.2 2.0 8.6 8 2 2 10 10 10 6 TPR repeat TPR_19 PF14559.1 KFY04048.1 - 5.5e-17 61.8 14.4 0.00012 22.3 0.2 7.9 5 2 1 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFY04048.1 - 7.3e-13 48.8 27.5 0.0045 17.6 0.0 7.9 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 KFY04048.1 - 1.1e-11 44.0 1.1 0.013 15.6 0.1 6.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 KFY04048.1 - 2.8e-11 43.2 33.7 0.00012 21.9 2.3 8.0 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 KFY04048.1 - 3.6e-11 42.6 21.2 0.0022 18.4 0.0 10.2 7 2 4 12 12 11 3 Tetratricopeptide repeat TPR_8 PF13181.1 KFY04048.1 - 3.6e-11 42.0 20.1 0.0013 18.3 0.1 8.1 6 2 2 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFY04048.1 - 1.8e-06 27.2 39.1 5.2e-05 22.6 0.2 10.7 12 0 0 12 12 12 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KFY04048.1 - 8.2e-06 26.0 1.5 0.23 11.7 0.0 3.6 3 0 0 3 3 3 2 Alkyl sulfatase dimerisation TPR_2 PF07719.12 KFY04048.1 - 9.7e-06 25.1 39.5 0.0015 18.3 0.1 12.2 14 0 0 14 14 14 2 Tetratricopeptide repeat Apc3 PF12895.2 KFY04048.1 - 0.00017 21.6 29.3 0.0015 18.6 3.0 6.4 6 1 1 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 KFY04048.1 - 0.00042 20.3 16.9 0.066 13.3 1.4 5.9 5 2 1 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 KFY04048.1 - 0.00096 19.4 20.2 0.25 11.8 0.1 7.8 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFY04048.1 - 0.011 15.5 23.2 0.053 13.3 0.1 7.4 9 0 0 9 9 7 0 Tetratricopeptide repeat DUF2098 PF09871.4 KFY04048.1 - 3.1 7.7 7.5 0.54 10.2 0.6 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2098) Sec23_trunk PF04811.10 KFY04049.1 - 1.3e-80 270.2 0.0 1.8e-80 269.7 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KFY04049.1 - 1.1e-33 114.6 0.2 2.9e-33 113.3 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KFY04049.1 - 7.4e-31 106.5 0.3 1.8e-30 105.2 0.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KFY04049.1 - 2.2e-16 59.1 5.9 4.6e-16 58.0 4.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KFY04049.1 - 3e-13 49.2 0.0 8.2e-13 47.8 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat Ribosomal_L22 PF00237.14 KFY04050.1 - 9.7e-35 118.6 0.1 1.3e-34 118.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e PPV_E1_N PF00524.13 KFY04062.1 - 1.4 9.1 4.6 1.8 8.7 1.6 1.9 1 1 1 2 2 2 0 E1 Protein, N terminal domain FMN_dh PF01070.13 KFY04063.1 - 1.1e-120 402.7 0.1 1.5e-120 402.3 0.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KFY04063.1 - 2.6e-22 78.4 0.0 5.6e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Synaptobrevin PF00957.16 KFY04063.1 - 1.1e-12 47.3 0.5 1.1e-12 47.3 0.3 1.9 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.1 KFY04063.1 - 1.5e-11 43.6 0.0 3.3e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain Glu_synthase PF01645.12 KFY04063.1 - 8.7e-09 34.7 0.1 1.5e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KFY04063.1 - 0.0015 17.5 0.3 0.0036 16.2 0.2 1.6 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 KFY04063.1 - 0.05 12.6 0.2 1.1 8.3 0.1 2.4 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KFY04063.1 - 0.086 12.0 0.6 2.7 7.2 0.1 2.3 1 1 0 2 2 2 0 Histidine biosynthesis protein HMGL-like PF00682.14 KFY04064.1 - 2.3e-70 236.9 0.1 4.3e-70 236.0 0.1 1.5 1 0 0 1 1 1 1 HMGL-like Glyco_hydro_61 PF03443.9 KFY04065.1 - 8.4e-50 169.5 0.0 9.4e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cadherin_pro PF08758.6 KFY04065.1 - 0.0023 17.6 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 Cadherin prodomain like WD40 PF00400.27 KFY04068.1 - 3.8e-27 93.1 0.2 1.2e-13 50.3 0.1 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 KFY04068.1 - 0.016 13.3 0.1 0.019 13.0 0.1 1.3 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Transposase_28 PF04195.7 KFY04068.1 - 0.053 12.8 0.0 0.078 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative gypsy type transposon Glyco_hydro_18 PF00704.23 KFY04070.1 - 4.9e-82 276.1 1.4 6.4e-82 275.7 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 F-box PF00646.28 KFY04071.1 - 0.12 12.0 0.1 0.36 10.5 0.1 1.8 1 0 0 1 1 1 0 F-box domain Cyto_ox_2 PF02322.10 KFY04072.1 - 0.14 11.3 5.1 0.2 10.7 3.5 1.3 1 1 0 1 1 1 0 Cytochrome oxidase subunit II DUF3723 PF12520.3 KFY04073.1 - 1e-108 364.1 0.0 1.2e-108 363.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Gin PF10764.4 KFY04073.1 - 0.08 12.6 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Inhibitor of sigma-G Gin Abhydrolase_6 PF12697.2 KFY04074.1 - 5e-12 46.1 1.6 8.2e-12 45.4 1.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFY04074.1 - 3.1e-10 39.9 0.1 5.2e-10 39.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY04074.1 - 0.00059 19.4 0.0 0.00088 18.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KFY04074.1 - 0.14 11.9 0.1 0.33 10.8 0.1 1.6 1 1 0 1 1 1 0 Putative lysophospholipase Nucleoplasmin PF03066.10 KFY04075.1 - 5.6 6.4 9.7 8.8 5.8 6.7 1.5 1 0 0 1 1 1 0 Nucleoplasmin HR1 PF02185.11 KFY04076.1 - 0.94 9.2 11.8 2 8.2 0.1 3.4 4 0 0 4 4 4 0 Hr1 repeat DUF221 PF02714.10 KFY04077.1 - 3.2e-97 325.2 26.6 3.2e-97 325.2 18.4 2.2 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KFY04077.1 - 5.1e-41 139.8 1.6 5.1e-41 139.8 1.1 3.8 3 1 1 4 4 4 1 Late exocytosis, associated with Golgi transport HlyIII PF03006.15 KFY04077.1 - 5.1e-36 124.1 14.8 5.1e-36 124.1 10.3 4.3 4 1 0 4 4 4 1 Haemolysin-III related DUF3779 PF12621.3 KFY04077.1 - 1.9e-11 43.6 0.0 7e-11 41.8 0.0 2.0 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KFY04077.1 - 1.1e-08 35.4 8.8 0.00051 20.4 0.2 3.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4463) DDHD PF02862.12 KFY04078.1 - 0.032 14.0 2.2 1.8 8.2 0.8 2.2 2 0 0 2 2 2 0 DDHD domain Transketolase_N PF00456.16 KFY04078.1 - 0.091 11.5 1.6 0.12 11.1 1.1 1.1 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain DUF4355 PF14265.1 KFY04078.1 - 0.47 10.4 13.4 0.85 9.5 9.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Ank_2 PF12796.2 KFY04079.1 - 2.6e-93 306.4 24.2 3.6e-21 75.2 0.1 4.2 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFY04079.1 - 3.2e-57 187.6 14.0 3.7e-09 35.9 0.0 8.7 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 KFY04079.1 - 1.3e-41 140.2 10.6 2.6e-08 34.1 0.0 6.1 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY04079.1 - 1.1e-38 127.3 9.6 1.2e-06 28.2 0.0 8.6 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 KFY04079.1 - 2.7e-34 116.4 14.5 1e-07 31.9 0.1 7.7 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 KFY04079.1 - 0.16 11.4 0.2 18 4.7 0.0 2.8 3 0 0 3 3 3 0 Shigella flexneri OspC protein WD40 PF00400.27 KFY04080.1 - 1.8e-131 423.8 49.2 3.5e-13 48.8 0.2 11.8 11 0 0 11 11 11 11 WD domain, G-beta repeat Nup160 PF11715.3 KFY04080.1 - 7.1e-17 60.7 41.3 0.023 12.8 1.0 11.2 1 1 7 8 8 8 8 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KFY04080.1 - 2.1e-11 43.2 37.8 0.00019 20.3 3.1 6.3 1 1 5 6 6 6 6 Nup133 N terminal like Nbas_N PF15492.1 KFY04080.1 - 1.9e-10 40.3 22.8 0.077 12.0 0.1 9.2 1 1 8 10 10 10 5 Neuroblastoma-amplified sequence, N terminal NACHT PF05729.7 KFY04080.1 - 3.9e-08 33.1 0.0 1.2e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KFY04080.1 - 6.6e-07 29.4 0.1 2.5e-06 27.5 0.1 2.0 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 KFY04080.1 - 0.00086 19.0 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 KFY04080.1 - 0.0012 18.9 0.1 0.087 12.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain NYD-SP28_assoc PF14775.1 KFY04080.1 - 0.0025 17.4 4.0 35 4.1 0.0 6.8 8 0 0 8 8 8 0 Sperm tail C-terminal domain WXG100 PF06013.7 KFY04080.1 - 0.0043 17.0 4.4 13 5.9 0.0 5.6 5 0 0 5 5 5 0 Proteins of 100 residues with WXG AAA_18 PF13238.1 KFY04080.1 - 0.016 15.4 0.0 0.12 12.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain FlxA PF14282.1 KFY04080.1 - 0.027 14.3 0.1 0.12 12.3 0.1 2.1 1 0 0 1 1 1 0 FlxA-like protein AAA_17 PF13207.1 KFY04080.1 - 0.092 13.5 0.4 1.1 10.0 0.0 3.0 3 1 0 3 3 3 0 AAA domain APS_kinase PF01583.15 KFY04080.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.24 KFY04080.1 - 0.11 12.6 0.3 0.89 9.7 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MAD PF05557.8 KFY04080.1 - 0.17 9.9 1.0 0.38 8.7 0.7 1.5 1 0 0 1 1 1 0 Mitotic checkpoint protein bZIP_1 PF00170.16 KFY04086.1 - 3.3e-09 36.5 11.6 9.4e-09 35.1 8.0 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFY04086.1 - 2e-05 24.3 10.4 2e-05 24.3 7.2 2.3 2 0 0 2 2 2 1 Basic region leucine zipper DUF904 PF06005.7 KFY04086.1 - 0.025 14.8 0.9 0.025 14.8 0.6 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF904) DivIC PF04977.10 KFY04086.1 - 0.2 11.1 8.6 1.7 8.1 0.6 2.6 2 0 0 2 2 2 0 Septum formation initiator adh_short PF00106.20 KFY04087.1 - 2.3e-15 56.8 0.8 4.8e-15 55.8 0.5 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFY04087.1 - 1.7e-07 31.0 0.6 2.9e-07 30.3 0.4 1.3 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.13 KFY04088.1 - 0.003 16.4 0.0 0.0046 15.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain cobW PF02492.14 KFY04089.1 - 2.9e-43 147.3 0.3 5.3e-43 146.5 0.2 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NOT2_3_5 PF04153.13 KFY04089.1 - 1.2e-31 109.3 1.1 1.2e-31 109.3 0.8 1.7 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family CobW_C PF07683.9 KFY04089.1 - 0.00026 20.6 0.0 0.00067 19.3 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain DUF258 PF03193.11 KFY04089.1 - 0.009 15.2 0.1 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KFY04089.1 - 0.016 15.3 0.1 0.35 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KFY04089.1 - 0.022 14.4 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase GTP_EFTU PF00009.22 KFY04089.1 - 0.034 13.5 1.0 0.48 9.8 0.7 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 KFY04089.1 - 0.041 13.4 0.4 0.16 11.5 0.3 1.9 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 KFY04089.1 - 0.052 12.9 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Septin PF00735.13 KFY04089.1 - 0.083 11.8 0.2 11 4.8 0.0 2.2 2 0 0 2 2 2 0 Septin ArgK PF03308.11 KFY04089.1 - 0.092 11.5 0.5 4.7 5.8 0.0 2.4 3 0 0 3 3 3 0 ArgK protein AAA_19 PF13245.1 KFY04089.1 - 0.13 12.0 0.1 0.34 10.6 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain MMR_HSR1 PF01926.18 KFY04089.1 - 0.13 12.2 0.1 0.33 10.9 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 KFY04089.1 - 0.13 12.5 0.1 0.4 10.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain Mob1_phocein PF03637.12 KFY04090.1 - 6.4e-24 84.5 0.1 1e-23 83.9 0.1 1.2 1 0 0 1 1 1 1 Mob1/phocein family Na_Ca_ex PF01699.19 KFY04091.1 - 6.4e-27 93.8 24.0 8.7e-16 57.7 5.7 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Wzy_C PF04932.10 KFY04091.1 - 6.3 6.5 12.5 55 3.5 0.1 3.3 1 1 1 2 2 2 0 O-Antigen ligase Sdh_cyt PF01127.17 KFY04091.1 - 8.9 6.1 16.0 4 7.2 0.0 4.4 3 2 1 4 4 4 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit RRM_6 PF14259.1 KFY04092.1 - 0.11 12.5 0.0 0.65 10.0 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DEAD PF00270.24 KFY04093.1 - 5.8e-25 87.7 0.0 1.1e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Yip1 PF04893.12 KFY04093.1 - 9.5e-14 51.2 8.8 1.9e-13 50.2 6.1 1.5 1 0 0 1 1 1 1 Yip1 domain DUF1998 PF09369.5 KFY04093.1 - 4.6e-13 49.5 0.2 1.2e-12 48.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Ran_BP1 PF00638.13 KFY04093.1 - 1.5e-12 47.5 0.1 1.9e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 RanBP1 domain Helicase_C PF00271.26 KFY04093.1 - 5e-10 39.0 0.1 1.7e-09 37.3 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDT1 PF08839.6 KFY04093.1 - 0.00059 19.8 0.1 0.0012 18.8 0.1 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like RNA_pol_Rpb4 PF03874.11 KFY04093.1 - 0.39 10.7 2.8 1.1 9.2 1.2 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb4 DUF1282 PF06930.7 KFY04093.1 - 0.49 10.0 4.1 0.95 9.0 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) WD40 PF00400.27 KFY04094.1 - 2.8e-19 68.1 13.1 4.8e-07 29.4 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KFY04094.1 - 0.0024 17.6 1.4 0.11 12.1 0.1 3.2 3 0 0 3 3 3 1 Transcription factor IIIC subunit delta N-term RNA_pol_I_TF PF04090.7 KFY04095.1 - 5.8e-07 28.9 0.0 5e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase I specific initiation factor SNF2_N PF00176.18 KFY04096.1 - 6e-68 228.8 0.0 1.1e-67 228.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFY04096.1 - 1.3e-10 40.9 0.0 3.5e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFY04096.1 - 1.3e-05 24.7 0.0 2.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 KFY04096.1 - 1.4e-05 24.6 5.7 2.9e-05 23.6 4.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KFY04096.1 - 0.0048 16.5 5.8 0.014 15.0 4.0 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFY04096.1 - 0.0049 16.5 8.6 0.017 14.8 5.9 1.9 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFY04096.1 - 0.0083 16.1 3.2 0.021 14.8 2.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KFY04096.1 - 0.031 14.0 3.3 0.073 12.9 2.3 1.7 1 0 0 1 1 1 0 Ring finger domain AftA_N PF12250.3 KFY04096.1 - 0.052 12.2 0.0 0.077 11.7 0.0 1.1 1 0 0 1 1 1 0 Arabinofuranosyltransferase N terminal PI3_PI4_kinase PF00454.22 KFY04097.1 - 8.9e-36 123.5 0.0 1.3e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GATA PF00320.22 KFY04098.1 - 2.6e-14 52.2 2.4 5.3e-14 51.2 1.6 1.6 1 0 0 1 1 1 1 GATA zinc finger DivIVA PF05103.8 KFY04098.1 - 0.085 12.9 7.4 0.13 12.3 5.2 1.2 1 0 0 1 1 1 0 DivIVA protein CENP-F_leu_zip PF10473.4 KFY04098.1 - 0.09 12.6 11.7 2.5 7.9 0.5 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2353 PF09789.4 KFY04098.1 - 0.11 11.7 7.6 0.16 11.2 5.3 1.1 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Atg14 PF10186.4 KFY04098.1 - 0.38 9.6 7.0 0.65 8.8 4.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SpecificRecomb PF10136.4 KFY04098.1 - 0.49 8.3 1.6 0.73 7.8 1.1 1.1 1 0 0 1 1 1 0 Site-specific recombinase Fmp27_WPPW PF10359.4 KFY04098.1 - 0.82 8.0 6.0 1.2 7.5 4.2 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Phlebovirus_NSM PF07246.6 KFY04098.1 - 0.95 8.5 4.3 1.5 7.9 3.0 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M IncA PF04156.9 KFY04098.1 - 1.1 8.7 8.1 1.9 8.0 5.6 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 KFY04098.1 - 1.4 7.9 6.8 2.4 7.1 4.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DivIC PF04977.10 KFY04098.1 - 3.1 7.3 9.5 1.9 8.0 2.9 2.2 2 0 0 2 2 2 0 Septum formation initiator Spermine_synth PF01564.12 KFY04099.1 - 1.9e-10 40.1 0.0 2.9e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 KFY04099.1 - 9.1e-08 32.1 0.2 2.4e-07 30.7 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY04099.1 - 2.6e-05 24.7 0.0 6.7e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY04099.1 - 0.0027 17.3 0.0 0.0051 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY04099.1 - 0.0041 17.5 0.0 0.011 16.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFY04099.1 - 0.012 15.2 0.0 0.031 13.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.6 KFY04099.1 - 0.054 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_11 PF08241.7 KFY04099.1 - 0.074 13.5 0.0 0.3 11.5 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Gly-zipper_OmpA PF13436.1 KFY04099.1 - 0.32 10.6 3.9 0.66 9.6 0.3 2.3 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain CorA PF01544.13 KFY04101.1 - 3.3e-08 32.8 0.7 5.3e-08 32.2 0.5 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Seipin PF06775.9 KFY04102.1 - 3.8e-33 114.6 0.0 5.3e-33 114.2 0.0 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) QCR10 PF09796.4 KFY04102.1 - 0.05 13.2 0.2 0.05 13.2 0.1 1.7 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Nic96 PF04097.9 KFY04103.1 - 1e-183 611.8 0.0 1.3e-183 611.4 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 UPF0029 PF01205.14 KFY04103.1 - 1.2e-26 92.5 0.0 2.6e-26 91.4 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Nucleoporin_FG PF13634.1 KFY04103.1 - 0.00068 19.8 35.9 0.00068 19.8 24.9 2.6 2 0 0 2 2 2 1 Nucleoporin FG repeat region VTC PF09359.5 KFY04105.1 - 4.7e-97 324.3 0.5 7.7e-97 323.7 0.4 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 KFY04105.1 - 1.1e-16 61.4 15.0 1.9e-12 47.5 7.2 3.7 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 KFY04105.1 - 2e-10 40.7 3.3 5.2e-10 39.3 2.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Seryl_tRNA_N PF02403.17 KFY04105.1 - 0.14 12.1 4.2 0.27 11.2 0.9 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Glu_synthase PF01645.12 KFY04106.1 - 6e-160 532.1 0.0 1.1e-159 531.3 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 KFY04106.1 - 2.6e-139 463.9 0.0 3.4e-139 463.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 KFY04106.1 - 5.7e-117 390.0 0.0 9.5e-117 389.3 0.0 1.4 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 KFY04106.1 - 7.2e-68 227.5 5.2 1.5e-67 226.5 3.6 1.5 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 KFY04106.1 - 5.7e-23 80.6 0.1 1.4e-22 79.4 0.1 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 KFY04106.1 - 7.7e-15 55.3 0.0 2.6e-14 53.5 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFY04106.1 - 1.6e-10 41.3 0.2 0.0005 20.1 0.0 2.6 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFY04106.1 - 2.6e-08 33.7 0.0 9.4e-08 31.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KFY04106.1 - 3.4e-07 30.5 0.0 0.00076 19.8 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFY04106.1 - 1.7e-05 23.5 0.0 4.9e-05 21.9 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.19 KFY04106.1 - 4.7e-05 22.6 0.0 7.5e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 KFY04106.1 - 9.7e-05 21.4 0.2 0.00032 19.7 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 KFY04106.1 - 0.00099 18.2 0.1 0.0047 16.0 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 KFY04106.1 - 0.001 18.0 0.1 0.0038 16.1 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 KFY04106.1 - 0.0014 18.8 1.8 1.4 9.1 0.0 3.0 3 0 0 3 3 2 2 Putative NAD(P)-binding AdoHcyase_NAD PF00670.16 KFY04106.1 - 0.0065 16.3 0.3 4.7 7.0 0.0 2.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FAD_binding_3 PF01494.14 KFY04106.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FMO-like PF00743.14 KFY04106.1 - 0.015 13.4 0.1 4.8 5.2 0.0 2.7 2 1 1 3 3 3 0 Flavin-binding monooxygenase-like NAD_Gly3P_dh_N PF01210.18 KFY04106.1 - 0.025 14.3 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.16 KFY04106.1 - 0.05 13.1 0.2 0.56 9.7 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 KFY04106.1 - 0.067 12.2 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase DJ-1_PfpI PF01965.19 KFY04106.1 - 0.11 11.9 0.4 3.2 7.1 0.1 2.4 1 1 1 2 2 2 0 DJ-1/PfpI family FMN_dh PF01070.13 KFY04106.1 - 0.12 11.1 0.8 0.41 9.4 0.5 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Apc15p PF05841.6 KFY04107.1 - 1.4e-19 71.0 0.4 1.4e-19 71.0 0.3 2.2 2 0 0 2 2 2 1 Apc15p protein SNARE PF05739.14 KFY04108.1 - 2e-09 36.9 1.6 2.8e-09 36.5 1.1 1.2 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 KFY04108.1 - 0.015 14.7 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 CHZ PF09649.5 KFY04109.1 - 5.9e-20 70.2 2.2 5.9e-20 70.2 1.5 2.6 3 0 0 3 3 3 1 Histone chaperone domain CHZ 6PF2K PF01591.13 KFY04110.1 - 1.8e-62 210.2 0.0 2.2e-43 147.9 0.0 2.3 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KFY04110.1 - 2.1e-24 86.3 0.0 7.1e-24 84.6 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KFY04110.1 - 0.00012 22.0 0.0 0.0015 18.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 KFY04110.1 - 0.022 14.0 0.0 0.07 12.3 0.0 1.8 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_17 PF13207.1 KFY04110.1 - 0.039 14.7 0.0 0.2 12.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KFY04110.1 - 0.043 12.9 0.0 0.094 11.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin CARD PF00619.16 KFY04110.1 - 0.055 13.2 0.3 0.21 11.4 0.2 2.0 1 1 0 1 1 1 0 Caspase recruitment domain Arm PF00514.18 KFY04111.1 - 1.6e-13 49.8 16.6 9.6e-06 25.2 0.1 9.5 11 0 0 11 11 11 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 KFY04111.1 - 1.8e-06 27.5 12.3 1.7 8.9 0.1 7.3 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.1 KFY04111.1 - 0.00023 21.3 10.7 3.4 8.0 0.0 6.3 6 1 1 7 7 7 3 HEAT repeats HEAT_EZ PF13513.1 KFY04111.1 - 0.0029 18.0 13.3 0.78 10.3 0.1 6.4 7 0 0 7 7 7 2 HEAT-like repeat V-ATPase_H_C PF11698.3 KFY04111.1 - 0.079 12.8 0.3 5.2 7.0 0.1 3.0 2 1 1 3 3 3 0 V-ATPase subunit H dCMP_cyt_deam_1 PF00383.17 KFY04112.1 - 2.7e-08 33.3 0.1 8.1e-08 31.8 0.0 1.8 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Cauli_VI PF01693.11 KFY04113.1 - 1.5e-33 114.5 3.2 2.7e-17 62.4 0.1 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 KFY04113.1 - 2.8e-26 92.4 0.0 4.9e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 RNase H Ank PF00023.25 KFY04114.1 - 3.2e-14 51.9 0.1 3e-07 29.9 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.19 KFY04114.1 - 4.6e-12 45.7 2.2 5.7e-12 45.4 0.2 2.1 2 0 0 2 2 2 1 IPT/TIG domain Ank_2 PF12796.2 KFY04114.1 - 8.6e-11 42.0 0.0 1.8e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFY04114.1 - 9.6e-09 34.6 0.1 0.00074 19.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KFY04114.1 - 2e-08 34.5 0.0 1.2e-07 32.0 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY04114.1 - 2.1e-08 34.1 0.1 0.00024 21.2 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Glyoxalase_2 PF12681.2 KFY04116.1 - 1.1e-06 29.1 0.0 1.4e-06 28.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 KFY04116.1 - 1.1e-05 25.4 0.0 1.5e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily adh_short PF00106.20 KFY04117.1 - 6.4e-15 55.4 2.7 2.3e-14 53.6 0.3 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Acetyltransf_1 PF00583.19 KFY04117.1 - 4.3e-11 42.6 0.0 1.2e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFY04117.1 - 7.1e-08 32.4 0.0 2.3e-07 30.8 0.0 1.9 2 0 0 2 2 1 1 Acetyltransferase (GNAT) domain KR PF08659.5 KFY04117.1 - 1.5e-07 31.2 0.1 6.8e-07 29.1 0.0 2.1 2 0 0 2 2 2 1 KR domain FR47 PF08445.5 KFY04117.1 - 6.6e-06 25.7 0.0 3.1e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 KFY04117.1 - 1e-05 25.6 0.0 4e-05 23.7 0.0 2.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain adh_short_C2 PF13561.1 KFY04117.1 - 0.00017 21.4 0.1 0.00025 20.9 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Acetyltransf_9 PF13527.1 KFY04117.1 - 0.00018 21.3 0.0 0.0096 15.7 0.0 2.7 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Epimerase PF01370.16 KFY04117.1 - 0.0005 19.5 0.1 0.00094 18.6 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFY04117.1 - 0.0095 15.9 1.5 0.024 14.6 0.7 2.1 1 1 1 2 2 2 1 NADH(P)-binding Acetyltransf_CG PF14542.1 KFY04117.1 - 0.026 14.4 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase 3Beta_HSD PF01073.14 KFY04117.1 - 0.052 12.2 0.1 0.079 11.6 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_31 PF13847.1 KFY04117.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KFY04118.1 - 5.4e-09 36.4 0.0 7.2e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFY04118.1 - 2.6e-05 23.9 0.0 3.9e-05 23.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY04118.1 - 3.4e-05 24.1 0.0 4.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY04118.1 - 0.00052 20.5 0.0 0.00096 19.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY04118.1 - 0.0007 19.2 0.0 0.00075 19.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY04118.1 - 0.0036 17.7 0.0 0.0059 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AATase PF07247.7 KFY04120.1 - 7.5e-23 80.8 0.0 1.4e-22 79.8 0.0 1.5 1 1 0 1 1 1 1 Alcohol acetyltransferase Glyco_hydro_61 PF03443.9 KFY04121.1 - 4e-79 265.4 0.0 4.6e-79 265.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 KFY04121.1 - 0.0075 16.3 0.1 0.031 14.3 0.0 2.0 2 0 0 2 2 2 1 NPCBM-associated, NEW3 domain of alpha-galactosidase Big_3_4 PF13754.1 KFY04121.1 - 0.019 15.3 0.1 0.074 13.3 0.1 2.2 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) GPI-anchored PF10342.4 KFY04121.1 - 0.046 14.1 0.2 3.6 8.1 0.1 2.4 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CFEM PF05730.6 KFY04122.1 - 1.4e-10 40.8 10.5 2.6e-10 39.9 7.3 1.5 1 0 0 1 1 1 1 CFEM domain HlyIII PF03006.15 KFY04131.1 - 8.2e-28 97.3 15.8 1.1e-27 96.8 11.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related BUD22 PF09073.5 KFY04132.1 - 0.62 9.0 17.7 0.71 8.8 12.3 1.0 1 0 0 1 1 1 0 BUD22 TFIIF_alpha PF05793.7 KFY04132.1 - 0.71 8.1 21.8 0.8 8.0 15.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1510 PF07423.6 KFY04132.1 - 2.1 7.6 14.9 2.7 7.2 10.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Presenilin PF01080.12 KFY04132.1 - 2.5 6.8 5.7 3.1 6.5 4.0 1.0 1 0 0 1 1 1 0 Presenilin Trypan_PARP PF05887.6 KFY04132.1 - 4.7 7.0 7.3 5.7 6.7 5.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) p450 PF00067.17 KFY04133.1 - 1.7e-49 168.6 0.0 2.6e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 zf-MYND PF01753.13 KFY04134.1 - 3.1e-10 39.7 6.1 3.1e-10 39.7 4.2 2.0 2 0 0 2 2 2 1 MYND finger Glucos_trans_II PF14264.1 KFY04135.1 - 0.0014 17.6 2.5 0.0014 17.6 1.7 1.8 2 0 0 2 2 2 1 Glucosyl transferase GtrII TrbL PF04610.9 KFY04135.1 - 0.005 16.5 2.2 0.005 16.5 1.5 2.5 3 0 0 3 3 3 1 TrbL/VirB6 plasmid conjugal transfer protein DUF4401 PF14351.1 KFY04135.1 - 0.27 10.1 9.2 0.13 11.2 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4401) SH3_1 PF00018.23 KFY04142.1 - 4.6e-09 35.5 0.0 7.8e-09 34.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KFY04142.1 - 1.2e-08 34.3 0.1 2.3e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KFY04142.1 - 8.3e-06 25.1 0.0 1.8e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain NMU PF02070.10 KFY04142.1 - 0.04 13.4 0.8 0.14 11.6 0.0 2.4 2 0 0 2 2 2 0 Neuromedin U Ssu72 PF04722.8 KFY04144.1 - 3.2e-85 284.3 0.0 3.7e-85 284.1 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein GIT_SHD PF08518.6 KFY04145.1 - 6.5e-23 79.7 5.5 4.4e-14 51.5 0.3 3.0 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT HCMV_UL139 PF12507.3 KFY04145.1 - 0.057 13.5 2.9 0.96 9.6 0.8 2.9 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein HALZ PF02183.13 KFY04145.1 - 0.18 11.5 13.0 0.51 10.0 1.0 3.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper NPV_P10 PF05531.7 KFY04145.1 - 1.6 9.0 11.5 0.48 10.7 0.2 4.6 2 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Tropomyosin_1 PF12718.2 KFY04145.1 - 2.7 7.8 45.8 2.1 8.1 13.2 4.3 2 1 2 4 4 4 0 Tropomyosin like Sugar_tr PF00083.19 KFY04147.1 - 8.3e-124 413.5 27.6 9.4e-124 413.4 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY04147.1 - 1.8e-25 89.4 52.6 9.2e-24 83.8 19.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFY04147.1 - 0.00012 20.6 4.9 0.00012 20.6 3.4 3.5 2 2 0 3 3 3 1 MFS/sugar transport protein TPR_19 PF14559.1 KFY04147.1 - 0.02 15.2 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 KFY04147.1 - 0.17 12.5 0.1 0.31 11.7 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF544 PF04424.8 KFY04154.1 - 7.1e-12 45.2 0.0 2.5e-11 43.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF544) CN_hydrolase PF00795.17 KFY04155.1 - 6.3e-26 90.8 0.0 1.3e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 KFY04155.1 - 7.8e-23 80.6 0.0 3.5e-22 78.4 0.0 2.0 1 1 0 1 1 1 1 NAD synthase HET PF06985.6 KFY04166.1 - 1.9e-20 73.4 4.6 3.2e-17 62.9 0.5 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ZZ PF00569.12 KFY04166.1 - 1.2e-05 24.7 10.2 2e-05 24.0 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-C2H2_jaz PF12171.3 KFY04168.1 - 2.6e-07 30.5 0.2 4.8e-07 29.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KFY04168.1 - 2.4e-05 24.3 0.3 4.4e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1777 PF08648.7 KFY04168.1 - 0.00012 21.8 11.5 0.00012 21.8 8.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) SDH_alpha PF03313.10 KFY04168.1 - 0.32 9.9 3.8 0.46 9.4 2.6 1.2 1 0 0 1 1 1 0 Serine dehydratase alpha chain Atg14 PF10186.4 KFY04168.1 - 1.1 8.1 7.4 1.8 7.4 5.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TP_methylase PF00590.15 KFY04169.1 - 1.3e-19 70.7 0.1 2.3e-19 69.9 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases CD52 PF15116.1 KFY04174.1 - 0.32 10.8 1.3 0.88 9.4 0.9 1.8 1 0 0 1 1 1 0 CAMPATH-1 antigen Acyltransferase PF01553.16 KFY04175.1 - 2.8e-24 85.0 0.0 4.2e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase NAD_kinase PF01513.16 KFY04176.1 - 5.5e-48 163.1 0.0 8.7e-48 162.5 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Acetyltransf_1 PF00583.19 KFY04177.1 - 2.7e-07 30.5 0.3 8.2e-07 28.9 0.0 1.9 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFY04177.1 - 0.00042 20.4 0.0 0.0015 18.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KFY04177.1 - 0.00053 20.0 0.1 0.002 18.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFY04177.1 - 0.0023 17.6 0.0 0.0053 16.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 KFY04177.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Cellulase PF00150.13 KFY04178.1 - 9.1e-52 175.9 1.7 1.1e-51 175.7 1.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KFY04178.1 - 2.9e-11 42.8 14.3 2.9e-11 42.8 9.9 2.4 2 0 0 2 2 2 1 Fungal cellulose binding domain Methyltransf_25 PF13649.1 KFY04179.1 - 7.8e-14 51.8 0.0 2e-13 50.5 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY04179.1 - 1.2e-12 48.3 0.0 2.1e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY04179.1 - 6.6e-12 45.7 0.0 1.1e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY04179.1 - 6.2e-11 42.0 0.0 8.2e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFY04179.1 - 1e-10 41.5 0.0 1.4e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFY04179.1 - 1.1e-08 35.0 0.0 2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY04179.1 - 4.3e-08 33.5 0.0 9.2e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFY04179.1 - 7.8e-06 25.3 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KFY04179.1 - 2.3e-05 23.6 0.0 3.5e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.9 KFY04179.1 - 5.9e-05 22.3 0.0 8.2e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Spermine_synth PF01564.12 KFY04179.1 - 0.00075 18.5 0.0 0.0013 17.7 0.0 1.3 1 1 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_20 PF12147.3 KFY04179.1 - 0.0061 15.4 0.0 0.0081 15.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_16 PF10294.4 KFY04179.1 - 0.0064 15.9 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase ApbA PF02558.11 KFY04179.1 - 0.02 14.3 0.0 0.23 10.9 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA RrnaAD PF00398.15 KFY04179.1 - 0.022 13.7 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_15 PF09445.5 KFY04179.1 - 0.027 14.0 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase 3HCDH_N PF02737.13 KFY04179.1 - 0.045 13.4 0.2 0.098 12.3 0.0 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NodS PF05401.6 KFY04179.1 - 0.055 12.8 0.0 0.12 11.7 0.0 1.6 1 1 0 1 1 1 0 Nodulation protein S (NodS) TPMT PF05724.6 KFY04179.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) UDPG_MGDP_dh_N PF03721.9 KFY04179.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.1 KFY04180.1 - 8.1e-26 91.3 0.0 2.3e-25 89.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KFY04180.1 - 7.4e-12 44.8 0.0 2.6e-09 36.4 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KFY04180.1 - 7.1e-10 39.1 0.0 4.3e-09 36.5 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFY04180.1 - 9.2e-09 34.0 0.0 2.1e-08 32.8 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 KFY04180.1 - 3.8e-05 23.5 0.2 0.083 12.6 0.0 3.6 3 1 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.19 KFY04180.1 - 0.00032 19.7 0.0 0.35 9.7 0.0 2.7 2 1 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 KFY04180.1 - 0.00085 18.4 0.1 0.0038 16.3 0.0 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 KFY04180.1 - 0.0014 18.5 0.0 0.0053 16.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KFY04180.1 - 0.044 12.2 0.1 1.7 7.0 0.1 2.3 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 KFY04180.1 - 0.17 10.7 0.1 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Gly_transf_sug PF04488.10 KFY04181.1 - 7.5e-21 74.4 0.1 1.6e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KFY04181.1 - 0.13 10.7 4.1 0.15 10.4 0.6 2.0 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain DNA_pol_A_exo1 PF01612.15 KFY04182.1 - 1.3e-09 37.8 0.0 2.2e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease p450 PF00067.17 KFY04183.1 - 3.7e-88 296.0 0.0 5.4e-88 295.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KFY04183.1 - 1.8e-22 79.5 25.9 4.7e-22 78.1 17.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily APH PF01636.18 KFY04183.1 - 1.9e-16 60.5 0.0 3.5e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFY04183.1 - 1.7e-06 27.8 0.0 3.1e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KFY04183.1 - 0.054 12.8 0.0 0.27 10.5 0.0 2.0 2 0 0 2 2 2 0 RIO1 family WD40 PF00400.27 KFY04184.1 - 1.1e-21 75.8 19.8 3.7e-07 29.7 0.3 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Cwf_Cwc_15 PF04889.7 KFY04184.1 - 0.044 13.4 6.5 0.091 12.4 4.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein eIF2A PF08662.6 KFY04184.1 - 0.052 13.2 0.0 0.94 9.1 0.0 2.6 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A FAM176 PF14851.1 KFY04184.1 - 0.99 9.0 2.6 2.4 7.8 1.8 1.6 1 0 0 1 1 1 0 FAM176 family Mg_trans_NIPA PF05653.9 KFY04185.1 - 3.4e-64 216.6 7.9 3.2e-62 210.1 3.3 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 KFY04185.1 - 0.0005 20.2 0.3 0.0005 20.2 0.2 3.3 3 1 1 4 4 4 1 Multidrug resistance efflux transporter LysE PF01810.13 KFY04185.1 - 0.0007 18.9 1.9 0.0007 18.9 1.3 2.4 2 1 1 3 3 3 1 LysE type translocator EamA PF00892.15 KFY04185.1 - 0.0029 17.6 3.0 0.0029 17.6 2.1 4.2 3 1 1 4 4 4 1 EamA-like transporter family DUF914 PF06027.7 KFY04185.1 - 0.013 14.4 5.4 0.056 12.2 0.1 2.2 1 1 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) DUF4401 PF14351.1 KFY04185.1 - 0.095 11.6 10.9 0.37 9.7 7.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4401) DUF4131 PF13567.1 KFY04185.1 - 1.4 8.3 4.6 4 6.8 0.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) DUF605 PF04652.11 KFY04185.1 - 9 5.5 10.4 17 4.7 7.2 1.4 1 0 0 1 1 1 0 Vta1 like TPR_11 PF13414.1 KFY04186.1 - 3.7e-09 36.0 0.6 1.5e-07 30.9 0.2 2.2 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 KFY04186.1 - 0.0012 18.5 3.7 0.73 9.8 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KFY04186.1 - 0.021 15.4 2.1 2.9 8.6 0.3 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KFY04186.1 - 0.031 14.2 0.6 1.9 8.4 0.1 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KFY04186.1 - 0.14 11.7 0.1 9.6 6.0 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KFY04186.1 - 0.25 11.2 0.8 3.4 7.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat HMG_box PF00505.14 KFY04190.1 - 0.034 14.4 0.0 0.066 13.4 0.0 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box RNA_pol_Rpb8 PF03870.10 KFY04195.1 - 4.4e-12 46.3 0.0 4.7e-12 46.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 NUDIX PF00293.23 KFY04196.1 - 2e-07 30.7 0.0 3.6e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF775 PF05603.7 KFY04197.1 - 6e-50 169.5 0.0 6.8e-50 169.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Nup_retrotrp_bd PF10599.4 KFY04197.1 - 1 10.0 8.1 0.36 11.4 2.5 2.1 1 1 1 2 2 2 0 Retro-transposon transporting motif GDA1_CD39 PF01150.12 KFY04198.1 - 1.2e-107 360.0 0.0 1.7e-107 359.6 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Adeno_E3_CR2 PF02439.10 KFY04198.1 - 0.31 10.6 1.0 0.59 9.7 0.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 zf-RING_5 PF14634.1 KFY04199.1 - 7.7e-08 31.9 6.6 1.2e-07 31.3 4.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KFY04199.1 - 9.6e-05 22.1 6.1 0.00017 21.3 4.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KFY04199.1 - 0.00012 22.0 7.0 0.00022 21.1 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFY04199.1 - 0.00041 19.9 7.0 0.00073 19.1 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KFY04199.1 - 0.0012 18.4 7.2 0.0022 17.6 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) LMBR1 PF04791.11 KFY04199.1 - 0.0033 16.0 0.2 0.0039 15.8 0.1 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein zf-rbx1 PF12678.2 KFY04199.1 - 0.018 15.1 2.1 0.036 14.1 1.4 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KFY04199.1 - 0.024 14.3 1.2 0.075 12.7 0.9 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KFY04199.1 - 0.024 14.4 5.5 0.049 13.5 3.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KFY04199.1 - 0.052 13.3 2.8 0.11 12.2 1.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 KFY04199.1 - 0.059 13.2 0.7 0.1 12.4 0.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger THOC7 PF05615.8 KFY04199.1 - 0.063 13.5 5.9 0.083 13.1 3.6 1.6 1 1 0 1 1 1 0 Tho complex subunit 7 zf-MIZ PF02891.15 KFY04199.1 - 0.088 12.3 4.5 0.16 11.5 3.1 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DNA_ligase_ZBD PF03119.11 KFY04199.1 - 0.094 12.4 3.4 0.43 10.3 0.2 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Drf_FH3 PF06367.11 KFY04199.1 - 0.1 12.0 5.4 0.17 11.2 3.8 1.3 1 0 0 1 1 1 0 Diaphanous FH3 Domain zf-RING_4 PF14570.1 KFY04199.1 - 0.31 10.6 2.6 0.61 9.7 1.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IncA PF04156.9 KFY04199.1 - 0.68 9.5 4.7 1 8.9 3.3 1.2 1 0 0 1 1 1 0 IncA protein DUF948 PF06103.6 KFY04199.1 - 0.68 9.8 2.7 1.3 8.9 1.8 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) RNA_POL_M_15KD PF02150.11 KFY04199.1 - 0.72 9.5 7.1 0.65 9.7 1.6 2.8 2 1 1 3 3 3 0 RNA polymerases M/15 Kd subunit DUF1272 PF06906.6 KFY04199.1 - 0.92 9.3 6.8 2.1 8.2 4.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) DUF342 PF03961.8 KFY04199.1 - 1.3 7.3 5.6 1.8 6.8 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Zn_Tnp_IS91 PF14319.1 KFY04199.1 - 6.6 6.2 8.3 13 5.3 1.8 2.9 1 1 1 3 3 3 0 Transposase zinc-binding domain OmpH PF03938.9 KFY04199.1 - 9.8 6.0 14.4 15 5.4 10.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Fungal_trans PF04082.13 KFY04200.1 - 1e-23 83.5 0.0 1.7e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY04200.1 - 3.4e-06 26.8 15.4 6e-06 26.0 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ThiF PF00899.16 KFY04201.1 - 1.1e-10 41.4 0.0 2.5e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 ThiF family Clr2 PF10383.4 KFY04202.1 - 4.3e-20 72.1 0.1 7.6e-20 71.3 0.1 1.4 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 SNF2_N PF00176.18 KFY04203.1 - 9.1e-60 201.9 0.0 5e-59 199.5 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFY04203.1 - 1.1e-11 44.3 0.3 1.2e-10 41.1 0.1 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KFY04203.1 - 2.7e-09 36.2 0.1 7.9e-08 31.4 0.0 2.4 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KFY04203.1 - 0.00054 19.8 0.0 0.0017 18.2 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PHD PF00628.24 KFY04203.1 - 0.0029 17.2 21.8 0.0041 16.7 6.4 3.3 1 1 1 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 KFY04203.1 - 0.48 10.3 17.6 0.7 9.7 3.2 2.6 2 0 0 2 2 2 0 Ring finger domain MARVEL PF01284.18 KFY04204.1 - 2.4e-06 27.4 6.9 3.6e-06 26.8 4.5 1.6 1 1 0 1 1 1 1 Membrane-associating domain DUF4271 PF14093.1 KFY04204.1 - 0.0036 17.0 0.7 0.013 15.2 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4271) DUF3899 PF13038.1 KFY04204.1 - 0.0046 17.0 0.8 1.6 8.9 0.3 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3899) DUF202 PF02656.10 KFY04204.1 - 0.032 14.4 1.4 4.5 7.5 0.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF202) ABC2_membrane_5 PF13346.1 KFY04204.1 - 0.052 12.8 0.3 0.052 12.8 0.2 1.8 2 0 0 2 2 2 0 ABC-2 family transporter protein COX4 PF02936.9 KFY04204.1 - 1.4 8.6 0.0 1.4 8.6 0.0 2.5 4 0 0 4 4 4 0 Cytochrome c oxidase subunit IV DUF3329 PF11808.3 KFY04204.1 - 1.6 8.8 0.0 1.6 8.8 0.0 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF3329) Pkinase PF00069.20 KFY04208.1 - 1.2e-15 57.3 0.0 1.9e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY04208.1 - 2.1e-14 53.2 0.0 3.3e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase NCA2 PF08637.5 KFY04208.1 - 0.00076 18.4 0.0 0.0043 16.0 0.0 1.9 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 Unstab_antitox PF09720.5 KFY04208.1 - 0.12 12.1 5.9 0.26 11.0 0.6 2.6 2 0 0 2 2 2 0 Putative addiction module component EURL PF06937.6 KFY04208.1 - 1.2 8.5 5.9 2.1 7.7 4.1 1.3 1 0 0 1 1 1 0 EURL protein Glyco_trans_2_3 PF13632.1 KFY04213.1 - 4.7e-48 163.4 1.3 4.7e-48 163.4 0.9 2.5 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 KFY04213.1 - 0.028 14.1 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF869 PF05911.6 KFY04217.1 - 0.0011 17.3 30.1 0.0011 17.3 20.9 1.9 2 0 0 2 2 2 1 Plant protein of unknown function (DUF869) DUF3584 PF12128.3 KFY04217.1 - 0.1 9.9 35.1 0.15 9.3 24.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1676 PF07898.8 KFY04217.1 - 0.38 11.0 9.1 1.6 9.1 6.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) DUF1664 PF07889.7 KFY04217.1 - 5 6.9 16.5 5.7 6.7 0.9 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Ank_2 PF12796.2 KFY04219.1 - 5.2e-68 225.4 21.8 6.8e-20 71.2 2.5 6.7 1 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFY04219.1 - 1e-63 208.1 42.4 8.5e-08 31.6 0.2 13.9 14 1 0 14 14 14 10 Ankyrin repeat Ank_4 PF13637.1 KFY04219.1 - 1.4e-47 159.2 18.9 8.9e-11 42.0 0.3 8.9 5 2 4 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY04219.1 - 7.3e-42 140.4 25.5 2.8e-08 33.7 0.9 10.4 5 2 5 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY04219.1 - 3.1e-41 135.2 25.8 0.00018 21.4 0.2 11.8 12 0 0 12 12 12 8 Ankyrin repeat DUF3447 PF11929.3 KFY04219.1 - 0.013 15.2 0.0 12 5.8 0.0 3.9 2 1 2 4 4 4 0 Domain of unknown function (DUF3447) F-box-like PF12937.2 KFY04220.1 - 0.0024 17.5 1.1 0.0048 16.5 0.8 1.6 1 0 0 1 1 1 1 F-box-like DUF1388 PF07142.7 KFY04222.1 - 0.0035 17.0 13.4 0.1 12.3 0.0 5.5 4 1 3 7 7 7 4 Repeat of unknown function (DUF1388) cobW PF02492.14 KFY04228.1 - 2.1e-46 157.6 2.2 3.8e-34 117.6 0.0 2.3 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KFY04228.1 - 2.5e-21 75.2 0.1 2e-15 56.2 0.0 2.8 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain AAA_22 PF13401.1 KFY04228.1 - 0.0094 16.0 0.0 0.048 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KFY04228.1 - 0.037 13.7 0.0 0.13 11.9 0.0 2.0 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 KFY04228.1 - 0.091 11.5 0.1 3.9 6.1 0.0 2.5 2 1 0 2 2 2 0 ArgK protein AAA_29 PF13555.1 KFY04228.1 - 0.096 12.2 0.2 0.21 11.1 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 KFY04228.1 - 0.097 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 KFY04228.1 - 0.11 12.1 0.1 0.25 10.9 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 G-alpha PF00503.15 KFY04228.1 - 0.87 8.2 4.8 0.34 9.5 0.4 2.1 2 0 0 2 2 2 0 G-protein alpha subunit PA14_2 PF10528.4 KFY04229.1 - 1.1e-20 73.6 0.2 1.8e-20 72.9 0.1 1.3 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.7 KFY04229.1 - 8.7e-09 35.1 0.1 1.9e-08 34.0 0.1 1.6 2 0 0 2 2 2 1 PA14 domain Stig1 PF04885.8 KFY04229.1 - 0.0085 16.3 22.6 0.013 15.6 15.7 1.2 1 0 0 1 1 1 1 Stigma-specific protein, Stig1 GMC_oxred_N PF00732.14 KFY04230.1 - 3.7e-30 105.1 0.0 3.8e-26 91.9 0.0 2.8 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 KFY04230.1 - 2.2e-28 99.3 0.0 3.5e-28 98.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KFY04230.1 - 3.8e-05 23.6 2.0 0.00011 22.1 1.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 KFY04230.1 - 0.0011 18.4 0.1 0.0023 17.3 0.1 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 KFY04230.1 - 0.0014 17.5 1.1 0.0022 16.8 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KFY04230.1 - 0.0017 18.2 0.0 0.0079 16.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFY04230.1 - 0.0033 16.3 1.6 0.027 13.3 0.8 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KFY04230.1 - 0.013 13.9 0.4 0.021 13.3 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 KFY04230.1 - 0.042 12.7 0.0 0.06 12.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ADH_zinc_N PF00107.21 KFY04231.1 - 3.8e-05 23.2 0.5 5.7e-05 22.6 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Zn_clus PF00172.13 KFY04232.1 - 3.5e-05 23.6 7.0 6.4e-05 22.7 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFY04232.1 - 0.00027 19.9 0.0 0.00054 18.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 KFY04233.1 - 2.5e-23 82.3 78.3 7.4e-23 80.8 33.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.23 KFY04234.1 - 8.7e-235 778.7 0.1 2.6e-82 276.4 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 KFY04234.1 - 1.6e-135 450.8 0.0 3.5e-39 134.4 0.1 4.8 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.20 KFY04234.1 - 9.3e-34 115.5 0.2 7.6e-13 48.5 0.0 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KFY04234.1 - 7.3e-14 52.4 0.1 0.00023 22.0 0.0 4.4 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain GH3 PF03321.8 KFY04234.1 - 0.69 8.3 0.2 1.7 7.0 0.0 1.7 2 0 0 2 2 2 0 GH3 auxin-responsive promoter FAD_binding_4 PF01565.18 KFY04236.1 - 2.1e-22 79.0 0.4 2.1e-22 79.0 0.3 2.4 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.14 KFY04236.1 - 2.6e-13 49.7 4.6 3.9e-07 29.4 2.4 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KFY04236.1 - 7e-09 35.0 3.1 0.00032 19.7 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFY04236.1 - 1.3e-08 34.0 0.3 2.7e-08 33.0 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KFY04236.1 - 5.8e-07 29.3 0.0 1.3e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like HI0933_like PF03486.9 KFY04236.1 - 6e-06 24.9 0.7 0.00078 18.0 0.5 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.2 KFY04236.1 - 5.2e-05 22.5 0.1 8.2e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFY04236.1 - 9.5e-05 22.3 0.7 0.00049 20.0 0.5 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFY04236.1 - 0.0021 18.1 0.1 0.0049 16.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFY04236.1 - 0.0028 16.5 0.5 0.0049 15.7 0.3 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KFY04236.1 - 0.0029 17.6 0.3 0.0029 17.6 0.2 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFY04236.1 - 0.0031 16.6 0.0 0.0066 15.5 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KFY04236.1 - 0.02 15.2 0.4 3.6 8.0 0.3 2.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KFY04236.1 - 0.042 12.9 0.1 1.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase 2OG-Fe_Oxy_2 PF10014.4 KFY04237.1 - 2.3e-43 147.8 0.4 3e-43 147.5 0.3 1.1 1 0 0 1 1 1 1 2OG-Fe dioxygenase HAD_2 PF13419.1 KFY04238.1 - 9e-33 113.9 0.0 1.4e-32 113.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KFY04238.1 - 0.022 15.1 0.0 0.28 11.5 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase SAP30_Sin3_bdg PF13867.1 KFY04238.1 - 0.022 14.5 0.1 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Aldolase_II PF00596.16 KFY04239.1 - 8.8e-43 146.0 0.2 1.1e-42 145.7 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain FAD_binding_3 PF01494.14 KFY04240.1 - 2.8e-14 52.9 8.7 3.8e-10 39.3 1.3 2.9 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KFY04240.1 - 9.9e-06 24.6 5.2 7.6e-05 21.7 1.2 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFY04240.1 - 1.3e-05 24.2 0.4 2.7e-05 23.2 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 KFY04240.1 - 0.00021 20.9 0.6 0.00044 19.8 0.1 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 KFY04240.1 - 0.00074 19.4 0.8 0.0023 17.8 0.4 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KFY04240.1 - 0.0034 16.5 0.6 0.0054 15.8 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFY04240.1 - 0.0092 15.9 0.6 0.026 14.5 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KFY04240.1 - 0.014 13.8 0.2 0.026 12.9 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 KFY04240.1 - 0.025 13.4 0.4 0.025 13.4 0.3 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.22 KFY04240.1 - 0.12 12.7 0.6 0.43 11.0 0.4 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFY04240.1 - 0.18 10.6 1.5 19 4.0 0.0 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 KFY04240.1 - 0.31 10.4 1.1 0.69 9.2 0.5 1.8 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AMP-binding PF00501.23 KFY04241.1 - 2.3e-73 247.0 0.0 3.2e-73 246.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 KFY04241.1 - 2.3e-22 79.2 2.2 1.7e-21 76.3 1.5 2.1 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.20 KFY04241.1 - 3.5e-11 43.2 0.0 8.9e-11 41.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KFY04241.1 - 0.0065 17.3 0.0 0.022 15.6 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Trypsin PF00089.21 KFY04242.1 - 7.2e-34 117.2 0.1 8.1e-34 117.1 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 KFY04242.1 - 3.3e-06 27.1 0.0 6.4e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Trypsin-like peptidase domain PH PF00169.24 KFY04248.1 - 5.4e-05 23.3 0.1 0.0001 22.4 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 KFY04248.1 - 9.3e-05 22.5 0.1 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain DUF1005 PF06219.7 KFY04248.1 - 0.0012 17.6 0.1 0.0021 16.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1005) Nucleoside_tran PF01733.13 KFY04249.1 - 1.6e-38 132.6 12.1 1.9e-24 86.4 2.4 2.7 3 0 0 3 3 3 2 Nucleoside transporter MFS_1 PF07690.11 KFY04249.1 - 0.44 9.2 47.9 21 3.7 33.9 2.1 1 1 0 1 1 1 0 Major Facilitator Superfamily A_deaminase PF00962.17 KFY04250.1 - 6e-37 127.2 0.0 8e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase PRP1_N PF06424.7 KFY04254.1 - 0.02 15.2 12.1 0.02 15.2 8.4 2.0 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Nucleo_P87 PF07267.6 KFY04254.1 - 0.061 12.0 12.0 0.13 10.9 8.3 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RNase_H2-Ydr279 PF09468.5 KFY04254.1 - 0.087 12.0 4.0 0.17 11.0 2.8 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Nucleoplasmin PF03066.10 KFY04254.1 - 5.6 6.4 12.6 0.12 11.9 4.0 1.7 2 0 0 2 2 2 0 Nucleoplasmin CDC45 PF02724.9 KFY04254.1 - 7.7 4.4 10.8 13 3.6 7.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Topoisom_bac PF01131.15 KFY04258.1 - 0.00026 19.9 0.0 0.00032 19.6 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase NUC129 PF08157.6 KFY04259.1 - 0.046 13.6 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 NUC129 domain Stb3 PF10330.4 KFY04260.1 - 5.2e-38 128.6 0.0 8.3e-38 127.9 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein MatE PF01554.13 KFY04261.1 - 5.1e-50 169.2 25.5 5.3e-31 107.4 4.2 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 KFY04261.1 - 9.2e-05 22.2 7.0 9.2e-05 22.2 4.9 4.2 3 2 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain PSI_PSAK PF01241.13 KFY04261.1 - 0.027 14.4 1.2 0.3 11.1 0.1 2.6 1 1 1 2 2 2 0 Photosystem I psaG / psaK DegT_DnrJ_EryC1 PF01041.12 KFY04262.1 - 3e-65 220.6 0.0 3.3e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3454 PF11936.3 KFY04263.1 - 0.1 12.8 3.6 0.33 11.1 2.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3454) DUF2205 PF10224.4 KFY04263.1 - 0.12 11.9 1.3 0.32 10.6 0.0 2.3 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) CCDC-167 PF15188.1 KFY04263.1 - 0.21 11.5 2.6 0.5 10.3 0.2 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4149 PF13664.1 KFY04264.1 - 1.2e-23 83.0 2.8 1.2e-23 83.0 1.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Ku_N PF03731.10 KFY04265.1 - 2.5e-22 79.4 0.0 3.2e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA_2 PF13519.1 KFY04265.1 - 3.6e-05 23.9 0.1 5.4e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KFY04265.1 - 0.011 15.5 0.1 0.017 14.8 0.1 1.3 1 1 0 1 1 1 0 von Willebrand factor type A domain Amino_oxidase PF01593.19 KFY04271.1 - 9.7e-35 120.5 0.2 5.8e-23 81.6 0.0 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Ank_2 PF12796.2 KFY04271.1 - 4.8e-25 87.7 0.6 2.1e-13 50.3 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFY04271.1 - 2.9e-14 53.1 0.8 2.6e-08 34.1 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KFY04271.1 - 3.3e-10 39.2 4.3 0.00015 21.4 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat NAD_binding_8 PF13450.1 KFY04271.1 - 5.6e-09 35.8 0.1 1.4e-08 34.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Ank_5 PF13857.1 KFY04271.1 - 2.6e-08 33.8 0.3 2.9e-06 27.3 0.2 3.2 1 1 2 3 3 3 2 Ankyrin repeats (many copies) DAO PF01266.19 KFY04271.1 - 2.9e-07 29.7 0.0 5.4e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Ank_3 PF13606.1 KFY04271.1 - 1.1e-05 25.1 3.0 0.096 12.9 0.0 3.6 3 0 0 3 3 2 2 Ankyrin repeat Pyr_redox PF00070.22 KFY04271.1 - 4e-05 23.9 0.1 0.00013 22.2 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFY04271.1 - 7.7e-05 22.8 0.0 0.00016 21.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFY04271.1 - 0.0012 18.0 0.0 0.0024 17.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KFY04271.1 - 0.002 17.2 0.2 0.0043 16.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KFY04271.1 - 0.0021 16.5 0.0 0.0045 15.5 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KFY04271.1 - 0.01 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KFY04271.1 - 0.018 14.7 0.0 0.061 12.9 0.0 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2346 PF09803.4 KFY04271.1 - 0.037 13.8 0.0 0.14 12.0 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) FAD_binding_2 PF00890.19 KFY04271.1 - 0.049 12.4 0.1 0.096 11.5 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Mnd1 PF03962.10 KFY04271.1 - 0.083 12.5 0.2 0.15 11.7 0.2 1.3 1 0 0 1 1 1 0 Mnd1 family NAD_binding_7 PF13241.1 KFY04271.1 - 0.098 12.9 0.0 0.48 10.7 0.0 2.2 2 0 0 2 2 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 KFY04271.1 - 0.11 12.3 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KFY04271.1 - 0.12 11.4 0.0 0.25 10.3 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase FMO-like PF00743.14 KFY04271.1 - 0.14 10.3 0.0 0.21 9.7 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like GIDA PF01134.17 KFY04271.1 - 0.14 10.9 0.1 0.29 9.9 0.1 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Translin PF01997.11 KFY04273.1 - 4e-52 176.7 0.0 4.6e-52 176.5 0.0 1.0 1 0 0 1 1 1 1 Translin family GMP_synt_C PF00958.17 KFY04273.1 - 0.041 13.6 0.0 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 GMP synthase C terminal domain PLU-1 PF08429.6 KFY04273.1 - 0.06 12.2 0.5 0.12 11.2 0.4 1.6 1 1 0 1 1 1 0 PLU-1-like protein DUF2411 PF10304.4 KFY04273.1 - 0.1 12.1 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) PIG-F PF06699.6 KFY04274.1 - 6.4e-46 156.7 5.6 8.9e-46 156.2 3.9 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Gly-zipper_Omp PF13488.1 KFY04274.1 - 0.14 11.7 10.8 0.41 10.3 0.5 2.6 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.1 KFY04274.1 - 4.6 6.8 13.8 28 4.3 9.0 2.4 1 1 0 1 1 1 0 YMGG-like Gly-zipper Tubulin PF00091.20 KFY04275.1 - 9.4e-73 244.5 0.0 1.4e-72 244.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KFY04275.1 - 1.7e-46 157.3 0.1 3.4e-46 156.3 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Mito_carr PF00153.22 KFY04275.1 - 2.2e-42 142.6 2.2 9.5e-19 66.9 0.1 4.3 4 0 0 4 4 4 3 Mitochondrial carrier protein GDPD PF03009.12 KFY04275.1 - 1.2e-32 113.4 0.0 2.2e-32 112.5 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Misat_Tub_SegII PF10644.4 KFY04275.1 - 3.3e-07 30.3 0.0 6.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain GDPD_2 PF13653.1 KFY04275.1 - 0.0021 18.1 0.4 0.0021 18.1 0.3 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ribosomal_L22e PF01776.12 KFY04276.1 - 3.1e-48 162.4 1.5 3.5e-48 162.2 1.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Reo_sigmaC PF04582.7 KFY04277.1 - 4.6 6.3 6.1 7.9 5.5 0.4 3.0 3 0 0 3 3 3 0 Reovirus sigma C capsid protein DUF2304 PF10066.4 KFY04279.1 - 4.8 7.0 13.9 0.3 10.9 1.3 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) ketoacyl-synt PF00109.21 KFY04283.1 - 1e-74 251.2 0.0 2.2e-74 250.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 KFY04283.1 - 2.3e-52 177.2 0.1 5.2e-52 176.1 0.1 1.6 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 KFY04283.1 - 4.1e-51 174.1 0.0 7.3e-51 173.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 KFY04283.1 - 6.1e-46 156.9 0.0 2.9e-45 154.7 0.0 2.0 1 1 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 KFY04283.1 - 3.9e-43 147.2 0.1 1.5e-42 145.3 0.0 2.2 2 0 0 2 2 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 KFY04283.1 - 6.1e-30 103.5 0.0 6.1e-30 103.5 0.0 2.2 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 KFY04283.1 - 1.7e-20 73.2 0.0 7.4e-20 71.2 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY04283.1 - 1.3e-15 57.3 0.1 4.4e-15 55.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFY04283.1 - 1.4e-15 57.3 0.0 3.9e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY04283.1 - 1.7e-15 57.2 0.0 4.3e-15 55.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY04283.1 - 4.1e-11 43.4 0.0 3.6e-10 40.4 0.0 2.8 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFY04283.1 - 2.9e-10 39.6 0.0 5.9e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KFY04283.1 - 2.1e-08 34.4 0.0 5.7e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 KFY04283.1 - 1.8e-05 23.8 0.0 3.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 KFY04283.1 - 2.4e-05 23.8 0.0 5.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 KFY04283.1 - 0.0022 17.9 0.0 0.0071 16.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KFY04283.1 - 0.0086 15.7 0.0 0.017 14.7 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase RrnaAD PF00398.15 KFY04283.1 - 0.023 13.7 0.0 0.047 12.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NodS PF05401.6 KFY04283.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) NNMT_PNMT_TEMT PF01234.12 KFY04283.1 - 0.16 10.8 0.0 2.5 7.0 0.0 2.2 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family MetW PF07021.7 KFY04283.1 - 0.19 11.0 0.0 1.4 8.2 0.0 2.4 3 0 0 3 3 3 0 Methionine biosynthesis protein MetW MoeZ_MoeB PF05237.8 KFY04283.1 - 0.26 10.9 0.0 0.65 9.6 0.0 1.6 1 0 0 1 1 1 0 MoeZ/MoeB domain Methyltransf_32 PF13679.1 KFY04283.1 - 0.34 10.5 0.1 1.2 8.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain DUF4106 PF13388.1 KFY04287.1 - 5.6 5.8 13.2 6.1 5.6 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF2439 PF10382.4 KFY04291.1 - 2.5e-26 91.6 0.9 3.7e-26 91.1 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2439) PI3_PI4_kinase PF00454.22 KFY04292.1 - 1.2e-50 172.1 0.0 2.6e-50 171.1 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 KFY04292.1 - 5.6e-41 140.6 7.8 9.4e-41 139.9 5.4 1.4 1 0 0 1 1 1 1 FAT domain UME PF08064.8 KFY04292.1 - 9.8e-31 105.8 0.2 1.4e-29 102.2 0.0 3.0 2 0 0 2 2 2 1 UME (NUC010) domain TPR_19 PF14559.1 KFY04292.1 - 0.024 14.9 3.0 0.049 13.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFY04292.1 - 0.099 13.3 5.4 8 7.4 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat COX16 PF14138.1 KFY04293.1 - 9.7e-34 115.3 0.1 1.2e-33 115.0 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 DnaJ PF00226.26 KFY04293.1 - 0.027 14.2 0.1 0.82 9.4 0.1 2.3 2 0 0 2 2 2 0 DnaJ domain Acetyltransf_1 PF00583.19 KFY04294.1 - 4.3e-10 39.4 0.0 6.4e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFY04294.1 - 1.6e-08 34.6 0.0 2.2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFY04294.1 - 2.1e-05 24.6 0.0 2.6e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KFY04294.1 - 3.4e-05 23.8 0.0 4.4e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFY04294.1 - 4.3e-05 23.1 0.0 7.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KFY04294.1 - 0.0016 18.3 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KFY04294.1 - 0.0023 17.5 0.0 0.0057 16.2 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KFY04294.1 - 0.036 13.9 0.0 0.07 13.0 0.0 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase BcrAD_BadFG PF01869.15 KFY04295.1 - 2.3e-18 66.4 0.3 3.7e-18 65.8 0.2 1.3 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family SIS PF01380.17 KFY04295.1 - 1.4e-05 24.7 1.9 4.6e-05 23.0 0.0 2.7 3 1 0 3 3 3 1 SIS domain SIS_2 PF13580.1 KFY04295.1 - 0.00016 21.4 0.1 0.0021 17.7 0.0 2.8 2 1 0 2 2 2 1 SIS domain Cas_csx3 PF09620.5 KFY04295.1 - 0.074 12.8 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) MFS_1 PF07690.11 KFY04296.1 - 1.7e-08 33.5 39.9 1.7e-08 33.5 27.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 KFY04296.1 - 2.4e-07 30.4 6.8 2.4e-07 30.4 4.7 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Beta-lactamase PF00144.19 KFY04297.1 - 7.8e-52 176.3 0.0 1e-51 175.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 KFY04297.1 - 0.0002 20.7 0.8 0.0018 17.5 0.1 2.5 2 1 1 3 3 3 1 D-alanyl-D-alanine carboxypeptidase DUF218 PF02698.12 KFY04298.1 - 1e-28 99.7 0.0 1.4e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain Methyltransf_11 PF08241.7 KFY04300.1 - 3.6e-10 40.1 0.0 6e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY04300.1 - 1.5e-07 31.0 0.0 2e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY04300.1 - 7.9e-07 29.6 0.0 1.2e-06 29.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY04300.1 - 1.7e-05 25.2 0.0 2.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY04300.1 - 0.00012 22.4 0.0 0.00024 21.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFY04300.1 - 0.001 18.4 0.0 0.0017 17.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KFY04300.1 - 0.0026 17.7 0.0 0.0065 16.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFY04300.1 - 0.0051 16.5 0.0 0.018 14.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain N2227 PF07942.7 KFY04300.1 - 0.0057 15.6 0.0 1.1 8.2 0.0 2.2 2 0 0 2 2 2 2 N2227-like protein Methyltransf_8 PF05148.10 KFY04300.1 - 0.039 13.5 0.0 0.61 9.6 0.0 2.5 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_32 PF13679.1 KFY04300.1 - 0.051 13.2 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.16 KFY04301.1 - 5.4e-10 39.1 0.2 1.3e-09 37.8 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFY04301.1 - 2.7e-06 27.5 0.3 4e-06 26.9 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KFY04301.1 - 3.2e-06 26.2 0.0 5e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KFY04301.1 - 0.0011 18.8 3.2 0.0021 18.0 0.2 2.4 2 1 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KFY04301.1 - 0.0011 17.6 0.0 0.002 16.8 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KFY04301.1 - 0.006 16.2 0.1 0.014 15.0 0.1 1.6 1 0 0 1 1 1 1 KR domain APH PF01636.18 KFY04302.1 - 2.5e-14 53.6 0.0 4.9e-14 52.6 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFY04302.1 - 5.3e-05 22.8 0.0 6.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KFY04302.1 - 0.0018 17.6 0.0 0.059 12.7 0.0 2.1 2 0 0 2 2 2 1 RIO1 family EcKinase PF02958.15 KFY04302.1 - 0.16 11.1 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase AIRC PF00731.15 KFY04303.1 - 2e-58 195.9 1.3 4.6e-58 194.7 0.9 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 KFY04303.1 - 5.7e-55 185.3 0.0 1.1e-54 184.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KFY04303.1 - 1.2e-11 44.7 0.0 2.2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 KFY04303.1 - 2.9e-07 29.9 0.0 5.3e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_Ter PF15632.1 KFY04303.1 - 0.0067 15.2 0.0 0.034 12.8 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Radical_SAM PF04055.16 KFY04303.1 - 0.019 15.1 0.0 4.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Radical SAM superfamily Dala_Dala_lig_C PF07478.8 KFY04303.1 - 0.019 14.3 0.0 0.37 10.1 0.0 2.2 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.14 KFY04303.1 - 0.073 12.2 0.0 0.18 10.9 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2OG-FeII_Oxy_2 PF13532.1 KFY04304.1 - 6.9e-22 78.2 0.0 1.9e-21 76.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.23 KFY04305.1 - 4.3e-77 259.2 0.0 5.3e-77 258.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFY04305.1 - 1.5e-11 45.0 0.1 4.3e-11 43.5 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Git3 PF11710.3 KFY04310.1 - 3.5e-05 23.4 0.9 3.9e-05 23.2 0.6 1.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 CS PF04969.11 KFY04316.1 - 1.1e-14 54.6 0.2 3.7e-14 53.0 0.0 2.0 2 1 0 2 2 2 1 CS domain MAT1 PF06391.8 KFY04317.1 - 2.1e-28 99.2 16.8 2.8e-28 98.9 11.7 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 DUF2096 PF09869.4 KFY04317.1 - 0.15 11.8 5.0 0.24 11.2 3.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) DUF4192 PF13830.1 KFY04317.1 - 0.99 8.9 11.1 1.9 8.0 7.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) HrpA_pilin PF09589.5 KFY04317.1 - 1.1 9.7 4.8 0.92 9.9 2.2 1.8 1 1 1 2 2 2 0 HrpA pilus formation protein Astro_capsid PF03115.9 KFY04317.1 - 1.4 7.0 4.9 1.8 6.7 3.4 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Prefoldin_3 PF13758.1 KFY04318.1 - 2.4e-28 97.7 1.2 6.4e-28 96.4 0.8 1.8 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.2 KFY04318.1 - 5.9e-21 75.2 11.7 1.1e-19 71.1 0.0 3.9 3 1 0 3 3 3 2 Domain of unknown function (DUF3835) MIS13 PF08202.6 KFY04318.1 - 0.0083 15.2 1.5 0.02 14.0 1.0 1.6 1 0 0 1 1 1 1 Mis12-Mtw1 protein family Noelin-1 PF12308.3 KFY04318.1 - 0.023 14.4 0.2 0.083 12.6 0.1 1.9 1 0 0 1 1 1 0 Neurogenesis glycoprotein FliJ PF02050.11 KFY04318.1 - 0.095 12.7 0.2 0.095 12.7 0.2 3.0 3 0 0 3 3 3 0 Flagellar FliJ protein ANTH PF07651.11 KFY04319.1 - 1.6e-66 223.8 0.4 2e-66 223.5 0.3 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 KFY04319.1 - 6.6e-10 38.9 0.0 1.1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 ENTH domain Methyltransf_2 PF00891.13 KFY04324.1 - 2.7e-29 102.0 0.0 4.4e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase HTH_IclR PF09339.5 KFY04324.1 - 0.033 13.7 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain PTR2 PF00854.16 KFY04325.1 - 2.5e-37 128.5 5.0 4.2e-37 127.8 1.6 2.4 2 1 0 2 2 2 1 POT family MFS_1 PF07690.11 KFY04325.1 - 1.9e-08 33.4 16.8 1.3e-07 30.6 12.3 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY04325.1 - 0.41 9.1 19.6 1.4 7.3 0.4 3.4 3 1 0 3 3 3 0 Sugar (and other) transporter DUF1469 PF07332.6 KFY04325.1 - 8.1 6.2 8.1 2 8.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) MFS_1 PF07690.11 KFY04326.1 - 1.5e-33 116.0 25.3 1.5e-33 116.0 17.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily FAA_hydrolase PF01557.13 KFY04327.1 - 3.9e-56 189.9 0.0 5.1e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans PF04082.13 KFY04328.1 - 1.7e-17 63.1 0.9 3e-17 62.3 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY04328.1 - 1.2e-07 31.5 15.1 2.2e-07 30.6 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4095 PF13338.1 KFY04328.1 - 0.09 12.9 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4095) Defensin_big PF14862.1 KFY04330.1 - 0.022 14.7 0.0 0.061 13.4 0.0 1.7 1 1 0 1 1 1 0 Big defensin Ank_2 PF12796.2 KFY04332.1 - 3.7e-76 251.5 24.9 1.3e-21 76.7 0.7 7.1 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFY04332.1 - 1e-40 137.3 16.0 6.4e-12 45.6 0.1 10.2 7 3 2 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.25 KFY04332.1 - 4e-40 133.6 41.3 3.1e-09 36.1 0.1 14.6 13 2 1 14 14 14 10 Ankyrin repeat Ank_5 PF13857.1 KFY04332.1 - 3e-35 119.4 21.6 3e-12 46.3 0.5 11.5 7 3 7 14 14 14 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY04332.1 - 1.3e-32 108.5 24.2 6.6e-05 22.7 0.0 13.8 13 1 1 14 14 14 11 Ankyrin repeat Shigella_OspC PF06128.6 KFY04332.1 - 0.054 12.9 0.1 0.58 9.5 0.0 2.5 2 0 0 2 2 2 0 Shigella flexneri OspC protein DUF3447 PF11929.3 KFY04332.1 - 0.07 12.9 0.1 2.1 8.1 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF3447) HATPase_c PF02518.21 KFY04333.1 - 3.3e-25 87.9 0.0 6.3e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KFY04333.1 - 7.4e-22 77.4 0.2 1.4e-21 76.5 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 KFY04333.1 - 1.8e-20 73.2 0.0 3.7e-14 52.9 0.0 2.6 2 0 0 2 2 2 2 PAS domain HisKA PF00512.20 KFY04333.1 - 1.4e-17 63.3 0.2 3.1e-17 62.3 0.1 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 KFY04333.1 - 1.1e-13 50.8 0.0 2.6e-07 30.4 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 KFY04333.1 - 2.5e-11 43.5 0.0 0.00016 21.6 0.0 2.5 2 0 0 2 2 2 2 PAS fold DER1 PF04511.10 KFY04336.1 - 5.5e-53 179.4 4.9 6.8e-53 179.1 3.4 1.0 1 0 0 1 1 1 1 Der1-like family PNRC PF15365.1 KFY04337.1 - 1.3e-06 28.2 3.4 1.3e-06 28.2 2.4 4.1 5 0 0 5 5 5 1 Proline-rich nuclear receptor coactivator zf-rbx1 PF12678.2 KFY04338.1 - 1.3e-35 121.2 13.7 1.6e-35 121.0 9.5 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KFY04338.1 - 3.7e-17 61.9 10.0 5e-17 61.5 6.9 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KFY04338.1 - 2.2e-07 30.6 12.1 1.3e-06 28.0 8.4 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KFY04338.1 - 0.0015 18.1 11.8 0.024 14.3 8.2 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KFY04338.1 - 0.0026 17.4 9.5 0.26 10.9 6.7 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KFY04338.1 - 0.04 13.9 12.7 0.043 13.8 5.6 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KFY04338.1 - 0.55 10.2 9.3 2.7 8.0 6.6 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.1 KFY04338.1 - 0.77 9.5 11.7 6.8 6.5 8.1 2.4 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 KFY04338.1 - 1.1 8.9 7.1 23 4.7 4.9 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H PF13771.1 KFY04338.1 - 2.5 8.2 10.7 1.2e+02 2.8 7.1 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain SPC12 PF06645.8 KFY04339.1 - 1.1e-27 95.6 0.1 1.3e-27 95.3 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MerC PF03203.9 KFY04339.1 - 0.0081 16.5 0.2 0.0086 16.4 0.1 1.1 1 0 0 1 1 1 1 MerC mercury resistance protein FAD_binding_4 PF01565.18 KFY04339.1 - 0.046 13.1 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain DUF3040 PF11239.3 KFY04339.1 - 0.16 12.0 2.6 0.23 11.5 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) MS_channel PF00924.13 KFY04339.1 - 0.54 9.5 4.5 0.93 8.7 3.1 1.4 1 1 0 1 1 1 0 Mechanosensitive ion channel CorA PF01544.13 KFY04340.1 - 1.3e-44 152.4 0.2 1.8e-44 151.9 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-Tim10_DDP PF02953.10 KFY04341.1 - 9.9e-24 82.4 2.0 1.3e-23 82.0 1.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ribosomal_L23eN PF03939.8 KFY04342.1 - 9.5e-22 76.7 7.8 2.2e-21 75.6 5.4 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 KFY04342.1 - 2.4e-16 59.4 1.5 5.1e-16 58.3 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 P2 PF07194.6 KFY04342.1 - 0.09 12.6 0.6 0.14 11.9 0.4 1.4 1 0 0 1 1 1 0 P2 response regulator binding domain DUF3321 PF11968.3 KFY04343.1 - 1.2e-88 296.4 0.0 1.5e-88 296.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 KFY04343.1 - 0.034 13.8 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Aa_trans PF01490.13 KFY04344.1 - 2.1e-61 207.6 25.9 2.6e-61 207.3 17.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein eRF1_2 PF03464.10 KFY04345.1 - 2.3e-46 157.3 0.4 5.7e-46 156.1 0.1 1.8 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.10 KFY04345.1 - 1e-39 135.2 0.9 2.1e-39 134.2 0.6 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KFY04345.1 - 3.2e-28 97.9 0.0 6.7e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 KFY04345.1 - 0.11 11.9 0.0 0.31 10.5 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PDT PF00800.13 KFY04346.1 - 3e-66 222.4 0.0 7.5e-66 221.1 0.0 1.7 2 0 0 2 2 2 1 Prephenate dehydratase MaoC_dehydratas PF01575.14 KFY04346.1 - 7.8e-06 25.2 0.0 1.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain Pterin_bind PF00809.17 KFY04346.1 - 0.063 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Pterin binding enzyme Hexokinase_1 PF00349.16 KFY04350.1 - 1e-56 191.5 0.0 1.4e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 KFY04350.1 - 4.3e-50 170.1 0.0 1.9e-44 151.7 0.0 2.3 2 0 0 2 2 2 2 Hexokinase Zn_clus PF00172.13 KFY04351.1 - 4.9e-06 26.3 8.5 8.2e-06 25.6 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cutinase PF01083.17 KFY04352.1 - 3.8e-52 176.6 1.9 4.6e-52 176.3 1.3 1.1 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 KFY04352.1 - 0.00014 21.5 0.1 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 KFY04352.1 - 0.00024 21.4 0.1 0.00034 20.9 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.20 KFY04352.1 - 0.00088 18.8 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PE-PPE PF08237.6 KFY04352.1 - 0.0018 17.7 0.2 0.0027 17.1 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain DUF2974 PF11187.3 KFY04352.1 - 0.0037 16.6 0.1 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 KFY04352.1 - 0.0062 16.2 0.3 0.0076 16.0 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFY04352.1 - 0.039 13.8 0.2 0.051 13.4 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family VirJ PF06057.6 KFY04352.1 - 0.067 12.9 0.0 0.28 10.9 0.0 1.8 1 1 1 2 2 2 0 Bacterial virulence protein (VirJ) MFS_1 PF07690.11 KFY04353.1 - 2e-35 122.1 34.0 3.1e-35 121.5 23.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily COesterase PF00135.23 KFY04354.1 - 2.4e-81 274.0 0.1 3.5e-81 273.5 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFY04354.1 - 4.2e-08 33.0 0.2 3.1e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KFY04354.1 - 0.0032 16.1 0.0 1.1 7.8 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Fungal_trans PF04082.13 KFY04355.1 - 5.2e-09 35.3 0.1 8.3e-09 34.6 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY04357.1 - 0.0099 15.7 13.1 0.0099 15.7 9.1 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AP_endonuc_2 PF01261.19 KFY04358.1 - 7.1e-25 87.5 0.0 9.9e-25 87.0 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel ADP_ribosyl_GH PF03747.9 KFY04359.1 - 5.2e-49 167.5 0.1 2.4e-46 158.8 0.0 2.5 2 1 0 2 2 2 1 ADP-ribosylglycohydrolase Glyco_hydro_43 PF04616.9 KFY04359.1 - 4.2e-30 104.8 6.8 4.2e-30 104.8 4.7 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 Gly-zipper_Omp PF13488.1 KFY04359.1 - 0.049 13.2 5.9 1.3 8.7 1.2 2.5 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.1 KFY04359.1 - 0.057 12.9 6.1 0.55 9.7 0.9 2.5 2 0 0 2 2 2 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 KFY04359.1 - 0.12 12.0 10.0 1.7 8.3 0.5 2.5 2 0 0 2 2 2 0 Glycine zipper 2TM domain Ribosomal_L7Ae PF01248.21 KFY04360.1 - 8.6e-24 82.8 0.0 9.7e-24 82.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HAD PF12710.2 KFY04360.1 - 0.14 12.2 0.0 0.16 12.1 0.0 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Dynamin_N PF00350.18 KFY04361.1 - 2.3e-29 102.3 0.0 6e-29 101.0 0.0 1.8 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KFY04361.1 - 9.7e-21 73.8 0.1 1.5e-20 73.1 0.1 1.3 1 0 0 1 1 1 1 Dynamin central region GED PF02212.13 KFY04361.1 - 0.0013 18.5 0.5 0.0041 16.9 0.3 1.9 1 1 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KFY04361.1 - 0.0016 18.4 0.0 0.0052 16.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFY04361.1 - 0.011 16.2 0.1 0.034 14.6 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 KFY04361.1 - 0.065 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zn_clus PF00172.13 KFY04362.1 - 3.8e-06 26.7 11.8 1.3e-05 24.9 8.2 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 KFY04362.1 - 0.038 14.3 1.9 0.038 14.3 1.3 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KFY04362.1 - 0.045 14.0 1.8 0.045 14.0 1.2 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type NmrA PF05368.8 KFY04363.1 - 3.1e-52 177.1 0.0 4.6e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFY04363.1 - 1.1e-10 41.8 0.0 2.8e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KFY04363.1 - 0.001 17.8 0.0 0.0016 17.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KFY04363.1 - 0.0021 18.0 0.1 0.0041 17.1 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain DFF-C PF09033.5 KFY04363.1 - 0.15 11.8 0.2 0.85 9.4 0.0 2.0 2 0 0 2 2 2 0 DNA Fragmentation factor 45kDa, C terminal domain VPS9 PF02204.13 KFY04368.1 - 4.9e-30 103.6 0.1 8.1e-30 102.9 0.1 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 KFY04368.1 - 1.8e-10 40.0 0.0 3.5e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 CUE domain HEAT_EZ PF13513.1 KFY04372.1 - 4.4e-20 71.5 4.8 2.8e-07 30.8 0.0 9.5 6 2 3 9 9 9 5 HEAT-like repeat HEAT_2 PF13646.1 KFY04372.1 - 1.8e-17 63.3 9.4 4.1e-06 26.9 0.4 6.9 3 2 3 7 7 7 4 HEAT repeats HEAT PF02985.17 KFY04372.1 - 2.9e-17 61.1 6.6 4.3e-06 26.3 0.0 9.1 11 0 0 11 11 8 3 HEAT repeat Vac14_Fab1_bd PF12755.2 KFY04372.1 - 3.6e-08 33.6 0.3 0.085 13.2 0.0 5.2 4 2 1 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KFY04372.1 - 2.4e-05 24.2 1.5 0.39 10.5 0.0 3.8 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 KFY04372.1 - 4.4e-05 22.0 0.3 0.00078 17.8 0.0 2.8 3 0 0 3 3 3 1 Adaptin N terminal region IBN_N PF03810.14 KFY04372.1 - 0.00023 21.0 3.6 0.031 14.1 0.2 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain MMS19_C PF12460.3 KFY04372.1 - 0.00073 18.3 2.8 0.0016 17.2 0.4 2.8 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal Arm PF00514.18 KFY04372.1 - 0.0011 18.6 0.5 14 5.7 0.0 5.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat ParcG PF10274.4 KFY04372.1 - 0.0052 16.7 0.3 0.063 13.1 0.1 2.7 2 1 1 3 3 3 1 Parkin co-regulated protein RsbRD_N PF14361.1 KFY04372.1 - 0.014 15.8 0.3 8.3 6.9 0.0 3.2 3 0 0 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF2454 PF10521.4 KFY04372.1 - 0.041 12.8 0.1 0.14 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2454) DUF2435 PF10363.4 KFY04372.1 - 0.11 12.3 1.2 1.4 8.8 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2435) DUF1546 PF07571.8 KFY04372.1 - 0.13 12.3 0.1 15 5.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) Acetyltransf_7 PF13508.1 KFY04373.1 - 2.8e-08 33.8 0.0 4.7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFY04373.1 - 8.6e-08 32.1 0.0 1.4e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KFY04373.1 - 0.00013 22.1 0.0 0.00021 21.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFY04373.1 - 0.00036 20.2 0.0 0.00062 19.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KFY04373.1 - 0.02 14.7 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FtsJ PF01728.14 KFY04374.1 - 4.6e-61 205.9 0.0 8.4e-61 205.1 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase DEAD PF00270.24 KFY04375.1 - 4.5e-42 143.4 0.1 8.3e-42 142.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFY04375.1 - 2.1e-20 72.3 0.0 1.1e-19 70.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KFY04375.1 - 0.032 14.3 0.1 0.084 13.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.7 KFY04375.1 - 0.32 10.8 11.9 0.7 9.7 8.2 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 UCH PF00443.24 KFY04376.1 - 1.8e-39 135.4 0.0 3.4e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KFY04376.1 - 2.2e-20 73.3 0.0 3.2e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SET PF00856.23 KFY04376.1 - 0.00013 22.2 1.3 0.07 13.4 0.0 3.8 4 1 0 4 4 4 2 SET domain Rhodanese PF00581.15 KFY04376.1 - 0.098 13.0 0.0 0.3 11.4 0.0 1.9 1 0 0 1 1 1 0 Rhodanese-like domain Vps16_N PF04841.8 KFY04377.1 - 6.6e-99 331.2 0.0 8.9e-99 330.7 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 KFY04377.1 - 1.4e-79 267.3 0.0 2.1e-79 266.7 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Coatomer_WDAD PF04053.9 KFY04377.1 - 0.02 13.7 0.0 4.3 6.0 0.0 3.1 3 0 0 3 3 3 0 Coatomer WD associated region FHA PF00498.21 KFY04378.1 - 4.9e-14 52.1 0.0 8.6e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 KFY04378.1 - 2.4e-05 24.0 10.3 4.4e-05 23.2 7.2 1.5 1 0 0 1 1 1 1 Ring finger domain MARVEL PF01284.18 KFY04378.1 - 0.0037 17.0 8.1 0.0068 16.2 5.6 1.5 1 0 0 1 1 1 1 Membrane-associating domain zf-C3HC4 PF00097.20 KFY04378.1 - 0.0043 16.6 8.0 0.0079 15.8 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KFY04378.1 - 0.079 13.0 6.4 0.16 12.1 4.5 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger PHD PF00628.24 KFY04378.1 - 0.17 11.5 6.1 0.37 10.5 4.3 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.1 KFY04378.1 - 0.27 10.9 6.8 0.51 10.1 4.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING-like PF08746.6 KFY04378.1 - 0.59 10.1 7.0 1.2 9.2 4.9 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_2 PF13923.1 KFY04378.1 - 1.1 9.3 10.8 2.2 8.3 7.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) OrfB_Zn_ribbon PF07282.6 KFY04378.1 - 3 7.5 5.2 32 4.2 0.9 2.5 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Peptidase_M16_C PF05193.16 KFY04379.1 - 6.8e-50 169.2 0.0 3e-49 167.1 0.0 2.1 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KFY04379.1 - 3e-43 147.1 0.0 5.5e-42 143.0 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Acyl_transf_3 PF01757.17 KFY04384.1 - 4.5e-09 35.5 27.1 1.2e-08 34.2 18.6 1.7 1 1 1 2 2 2 1 Acyltransferase family APG17 PF04108.7 KFY04387.1 - 2.5e-98 329.5 0.0 8.3e-98 327.8 0.0 1.7 1 1 0 1 1 1 1 Autophagy protein Apg17 B12-binding_2 PF02607.12 KFY04387.1 - 0.075 13.0 0.1 1.4 9.0 0.1 2.5 2 0 0 2 2 2 0 B12 binding domain DUF3618 PF12277.3 KFY04387.1 - 0.13 12.2 0.2 0.13 12.2 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) WXG100 PF06013.7 KFY04387.1 - 3.3 7.7 6.2 21 5.2 0.0 4.1 3 1 1 4 4 4 0 Proteins of 100 residues with WXG Pox_MCEL PF03291.11 KFY04402.1 - 1.7e-24 86.3 0.0 4.8e-17 61.8 0.0 2.4 2 1 0 2 2 2 2 mRNA capping enzyme zf-Nse PF11789.3 KFY04403.1 - 1.2e-15 56.7 0.0 2.4e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 KFY04403.1 - 0.0011 18.5 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger IncA PF04156.9 KFY04403.1 - 0.084 12.4 4.2 0.16 11.5 2.9 1.4 1 0 0 1 1 1 0 IncA protein MFS_1 PF07690.11 KFY04405.1 - 2.7e-42 144.7 30.9 2.7e-42 144.7 21.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KFY04405.1 - 7.4e-08 31.0 4.7 1.2e-07 30.4 3.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KFY04405.1 - 1e-06 27.6 28.8 1.4e-05 23.8 20.1 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter MAPEG PF01124.13 KFY04406.1 - 4.5e-15 55.3 3.1 6.7e-15 54.8 2.1 1.2 1 0 0 1 1 1 1 MAPEG family ABC2_membrane PF01061.19 KFY04407.1 - 9.2e-89 296.1 54.7 1.9e-48 164.4 13.0 3.7 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 KFY04407.1 - 8.5e-35 118.5 0.1 3.1e-28 97.4 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 KFY04407.1 - 9e-35 119.9 0.0 2.6e-17 63.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KFY04407.1 - 2.9e-13 49.6 41.3 2.9e-07 29.8 12.9 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 KFY04407.1 - 5.4e-08 32.4 0.1 0.0018 17.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_trans_N PF14510.1 KFY04407.1 - 9.4e-08 32.0 0.0 3.5e-07 30.2 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 KFY04407.1 - 2.6e-05 23.4 0.1 0.00034 19.8 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 KFY04407.1 - 4.2e-05 23.6 0.2 0.37 10.7 0.0 2.6 1 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KFY04407.1 - 9.6e-05 22.5 0.1 0.031 14.4 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KFY04407.1 - 0.00011 22.9 0.0 0.14 12.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KFY04407.1 - 0.00018 20.9 0.9 0.044 13.3 0.1 2.9 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KFY04407.1 - 0.00025 21.1 0.7 0.0035 17.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KFY04407.1 - 0.00027 21.2 0.3 0.037 14.3 0.1 3.0 2 1 0 2 2 2 1 AAA domain cobW PF02492.14 KFY04407.1 - 0.00034 20.1 0.1 0.0022 17.4 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KFY04407.1 - 0.0005 19.9 1.1 0.064 13.1 0.0 3.1 3 0 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KFY04407.1 - 0.00098 18.6 0.3 1.8 8.0 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family UPF0079 PF02367.12 KFY04407.1 - 0.0082 15.7 0.8 0.24 11.0 0.1 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 KFY04407.1 - 0.012 15.5 0.1 1.2 9.1 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.1 KFY04407.1 - 0.013 15.4 0.4 0.013 15.4 0.3 2.5 3 0 0 3 3 2 0 AAA domain AAA_10 PF12846.2 KFY04407.1 - 0.018 14.4 0.4 2.7 7.3 0.1 2.8 3 0 0 3 3 3 0 AAA-like domain NACHT PF05729.7 KFY04407.1 - 0.025 14.2 1.0 0.48 10.0 0.1 2.5 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.14 KFY04407.1 - 0.085 12.0 0.5 1.5 7.9 0.0 2.7 4 0 0 4 4 3 0 RecF/RecN/SMC N terminal domain Meiosis_expr PF15163.1 KFY04407.1 - 0.27 11.6 3.2 0.74 10.2 0.2 2.7 3 0 0 3 3 2 0 Meiosis-expressed AAA_15 PF13175.1 KFY04407.1 - 0.6 9.0 0.0 8.2 5.3 0.0 2.1 1 1 1 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 KFY04407.1 - 0.71 9.6 2.7 8.7 6.1 0.3 2.7 2 0 0 2 2 2 0 Part of AAA domain DUF373 PF04123.8 KFY04407.1 - 6.8 5.5 7.1 16 4.3 4.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF373) TPT PF03151.11 KFY04408.1 - 2.5e-06 27.2 4.0 6.3e-06 25.9 2.8 1.7 1 0 0 1 1 1 1 Triose-phosphate Transporter family zf-CCCH PF00642.19 KFY04414.1 - 1.3e-06 27.8 10.5 3.9e-06 26.4 2.3 2.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 KFY04415.1 - 1.2e-16 60.0 0.0 2.2e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY04415.1 - 5.8e-13 48.6 0.0 9.5e-13 47.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFY04415.1 - 6.2e-07 29.1 0.0 1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KFY04415.1 - 4.4e-06 27.0 0.9 4.4e-06 27.0 0.7 3.4 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 CCER1 PF15482.1 KFY04415.1 - 0.09 12.4 2.6 0.92 9.0 0.3 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing glutamate-rich protein family 1 Shadoo PF14999.1 KFY04415.1 - 4.7 7.0 25.1 0.025 14.4 3.5 2.3 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective BNR PF02012.15 KFY04416.1 - 1.4e-16 57.5 20.4 0.11 12.3 0.0 9.5 8 0 0 8 8 8 8 BNR/Asp-box repeat CBM_1 PF00734.13 KFY04416.1 - 1.1e-10 40.9 11.1 3.5e-10 39.3 7.7 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain PSII_BNR PF14870.1 KFY04416.1 - 0.0076 15.2 18.1 0.8 8.6 0.1 6.5 5 2 2 7 7 7 3 Photosynthesis system II assembly factor YCF48 Mo-co_dimer PF03404.11 KFY04416.1 - 0.011 15.3 0.2 5.5 6.6 0.0 4.1 4 0 0 4 4 4 0 Mo-co oxidoreductase dimerisation domain Fungal_trans PF04082.13 KFY04417.1 - 3e-33 114.7 0.4 1.4e-32 112.5 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY04417.1 - 1.3e-08 34.6 15.2 2e-08 33.9 10.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KOW PF00467.24 KFY04418.1 - 1.6e-08 33.9 1.3 3.5e-08 32.8 0.6 1.8 2 0 0 2 2 2 1 KOW motif adh_short PF00106.20 KFY04419.1 - 8.4e-12 45.3 0.4 1.2e-11 44.7 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFY04419.1 - 9.3e-08 32.1 0.0 1.2e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFY04419.1 - 2e-05 24.3 0.0 8.1e-05 22.3 0.0 1.9 1 1 0 1 1 1 1 KR domain PGM_PMM_III PF02880.11 KFY04419.1 - 0.048 13.7 0.0 0.076 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DUF883 PF05957.8 KFY04420.1 - 0.011 16.0 1.5 0.011 16.0 1.1 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Tup_N PF08581.5 KFY04420.1 - 0.46 10.7 8.3 0.17 12.0 0.3 2.9 1 1 2 3 3 3 0 Tup N-terminal Med9 PF07544.8 KFY04420.1 - 1 9.1 6.1 0.22 11.2 0.2 2.7 2 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF4200 PF13863.1 KFY04420.1 - 3.5 7.6 10.1 2.9 7.8 4.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) DUF4559 PF15112.1 KFY04420.1 - 4.3 6.4 6.9 0.41 9.7 1.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) IncA PF04156.9 KFY04420.1 - 5.7 6.4 9.2 20 4.6 6.2 2.0 1 1 0 1 1 1 0 IncA protein DUF1825 PF08855.5 KFY04423.1 - 0.018 15.0 0.2 0.039 13.9 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) TRAPPC10 PF12584.3 KFY04428.1 - 6.8e-22 77.5 0.0 1e-20 73.7 0.0 2.4 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 Methyltransf_23 PF13489.1 KFY04428.1 - 9.3e-19 67.7 0.0 2.1e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY04428.1 - 4.2e-08 33.5 0.0 1.1e-07 32.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY04428.1 - 8.3e-06 26.3 0.1 3.7e-05 24.2 0.0 2.2 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY04428.1 - 1.7e-05 24.4 0.0 4.1e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Foie-gras_1 PF11817.3 KFY04428.1 - 5e-05 22.9 0.4 0.00011 21.7 0.3 1.6 1 0 0 1 1 1 1 Foie gras liver health family 1 Methyltransf_12 PF08242.7 KFY04428.1 - 0.00017 21.9 0.0 0.0012 19.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY04428.1 - 0.0012 19.1 0.0 0.0034 17.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFY04428.1 - 0.0081 15.5 0.0 0.02 14.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 KFY04428.1 - 0.032 14.2 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 KFY04428.1 - 0.13 11.2 0.0 0.41 9.6 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 KFY04428.1 - 0.42 9.6 0.0 0.72 8.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) HlyIII PF03006.15 KFY04429.1 - 2.5e-57 193.8 17.2 3e-57 193.5 11.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF349 PF03993.7 KFY04429.1 - 2.8 8.1 4.9 18 5.5 0.1 2.6 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) FimP PF09766.4 KFY04430.1 - 5.6e-27 94.7 3.1 7.7e-27 94.2 2.2 1.1 1 0 0 1 1 1 1 Fms-interacting protein GOLGA2L5 PF15070.1 KFY04430.1 - 0.0027 16.2 4.3 0.0037 15.8 3.0 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 K-box PF01486.12 KFY04430.1 - 0.0058 16.4 0.3 0.0058 16.4 0.2 2.9 2 1 0 2 2 2 1 K-box region MIT PF04212.13 KFY04430.1 - 0.17 11.7 2.9 0.4 10.5 2.0 1.7 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain DUF4200 PF13863.1 KFY04430.1 - 0.74 9.7 11.4 0.087 12.7 0.5 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Cortex-I_coil PF09304.5 KFY04430.1 - 0.75 9.8 10.0 4 7.5 2.7 2.4 2 0 0 2 2 2 0 Cortexillin I, coiled coil AAA_13 PF13166.1 KFY04430.1 - 0.77 8.1 3.4 0.39 9.1 0.2 1.8 2 0 0 2 2 2 0 AAA domain DUF3450 PF11932.3 KFY04430.1 - 2.2 7.4 10.2 3.1 6.9 2.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Ubie_methyltran PF01209.13 KFY04433.1 - 2.2e-59 200.4 0.0 2.5e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KFY04433.1 - 1.1e-16 61.1 0.0 2e-16 60.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY04433.1 - 7.1e-12 45.1 0.0 7.9e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY04433.1 - 1.9e-09 37.7 0.0 2.7e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY04433.1 - 2.8e-08 34.1 0.0 3.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFY04433.1 - 7.3e-08 32.3 0.0 1e-07 31.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KFY04433.1 - 0.00046 19.8 0.0 0.0006 19.4 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_18 PF12847.2 KFY04433.1 - 0.00066 20.2 0.0 0.001 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFY04433.1 - 0.014 15.3 0.0 0.032 14.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain DUF2433 PF10360.4 KFY04434.1 - 2e-55 186.6 0.0 3.5e-55 185.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.2 KFY04434.1 - 0.0048 16.7 0.1 0.021 14.6 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF2360 PF10152.4 KFY04434.1 - 0.18 12.0 12.8 17 5.7 8.9 2.6 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) TFIIA PF03153.8 KFY04434.1 - 2.8 7.7 12.2 4.1 7.1 8.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 KFY04434.1 - 4.7 6.5 19.4 8.1 5.7 13.4 1.3 1 0 0 1 1 1 0 Vta1 like Miro PF08477.8 KFY04435.1 - 1.9e-36 125.1 0.0 4.3e-19 69.1 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 KFY04435.1 - 5.3e-33 112.6 0.0 9.9e-33 111.7 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 KFY04435.1 - 4e-31 106.1 0.1 7.1e-31 105.3 0.1 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 KFY04435.1 - 9.2e-26 90.1 0.0 1.1e-15 57.3 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 KFY04435.1 - 3.7e-09 36.5 0.0 0.00016 21.5 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.1 KFY04435.1 - 1.4e-08 34.7 0.3 0.00029 20.8 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KFY04435.1 - 2.1e-08 32.8 1.8 0.0061 15.7 0.3 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KFY04435.1 - 5.8e-07 28.8 2.1 0.032 14.1 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain Dynamin_N PF00350.18 KFY04435.1 - 9.2e-07 28.8 0.9 0.1 12.3 0.0 3.8 3 1 1 4 4 4 2 Dynamin family AAA_16 PF13191.1 KFY04435.1 - 1.4e-06 28.4 0.0 0.078 12.9 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain EF-hand_5 PF13202.1 KFY04435.1 - 2.3e-05 23.5 3.6 0.032 13.5 1.2 2.7 2 0 0 2 2 2 2 EF hand AAA_22 PF13401.1 KFY04435.1 - 2.7e-05 24.3 0.0 0.018 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KFY04435.1 - 0.00013 21.3 0.0 0.099 12.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain EF-hand_8 PF13833.1 KFY04435.1 - 0.00023 20.7 1.5 0.72 9.5 0.8 2.6 2 0 0 2 2 2 2 EF-hand domain pair AAA_28 PF13521.1 KFY04435.1 - 0.0006 19.8 0.0 0.44 10.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KFY04435.1 - 0.0013 18.3 0.0 0.075 12.7 0.1 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KFY04435.1 - 0.0037 17.4 0.0 0.15 12.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase GTP_EFTU PF00009.22 KFY04435.1 - 0.0041 16.5 0.0 6.4 6.1 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_25 PF13481.1 KFY04435.1 - 0.0072 15.7 0.0 2.5 7.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KFY04435.1 - 0.026 14.2 0.0 2.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 KFY04435.1 - 0.026 14.1 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain EF-hand_10 PF14788.1 KFY04435.1 - 0.036 13.7 0.2 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 EF hand AAA_33 PF13671.1 KFY04435.1 - 0.043 13.6 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KFY04435.1 - 0.076 12.4 0.0 6.4 6.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.8 KFY04435.1 - 0.093 11.6 0.0 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 KFY04435.1 - 0.1 12.8 0.0 5.7 7.2 0.0 2.4 2 0 0 2 2 2 0 ABC transporter WD40 PF00400.27 KFY04437.1 - 2.9e-21 74.5 12.1 1.5e-06 27.8 0.4 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 KFY04437.1 - 1.6e-05 24.6 0.0 0.00075 19.2 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KFY04437.1 - 0.00012 20.1 0.0 0.00016 19.7 0.0 1.1 1 0 0 1 1 1 1 IKI3 family Cytochrom_D1 PF02239.11 KFY04437.1 - 0.0071 14.6 0.0 0.028 12.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome D1 heme domain PD40 PF07676.7 KFY04437.1 - 0.057 13.1 0.1 12 5.6 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.1 KFY04437.1 - 0.11 12.8 0.3 15 6.0 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain TFIIA PF03153.8 KFY04440.1 - 7.6 6.3 9.7 8.8 6.1 6.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EGF_2 PF07974.8 KFY04441.1 - 0.00028 20.9 6.8 0.00059 19.9 4.7 1.6 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 KFY04441.1 - 0.0016 18.3 4.4 0.0043 17.0 3.1 1.8 1 0 0 1 1 1 1 Human growth factor-like EGF Laminin_EGF PF00053.19 KFY04441.1 - 0.21 11.5 4.3 0.4 10.6 3.0 1.4 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) EGF PF00008.22 KFY04441.1 - 0.29 11.1 2.4 1.1 9.2 1.6 2.0 1 1 0 1 1 1 0 EGF-like domain PHD PF00628.24 KFY04442.1 - 9.5e-08 31.6 12.5 1.5e-07 30.9 8.6 1.3 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.10 KFY04442.1 - 0.11 12.1 5.4 0.24 11.1 3.7 1.5 1 0 0 1 1 1 0 CW-type Zinc Finger Iso_dh PF00180.15 KFY04444.1 - 1.3e-123 412.3 0.0 1.5e-123 412.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase LIM PF00412.17 KFY04445.1 - 0.0038 17.2 8.3 0.0038 17.2 5.7 2.3 2 0 0 2 2 2 1 LIM domain Cation_efflux PF01545.16 KFY04446.1 - 4.8e-54 183.3 1.0 6.5e-54 182.9 0.7 1.1 1 0 0 1 1 1 1 Cation efflux family SIR2 PF02146.12 KFY04447.1 - 4e-30 104.8 0.0 6.3e-30 104.2 0.0 1.3 1 1 0 1 1 1 1 Sir2 family SCP1201-deam PF14428.1 KFY04448.1 - 0.098 12.3 0.5 0.65 9.6 0.3 2.0 2 0 0 2 2 2 0 SCP1.201-like deaminase DUF1654 PF07867.6 KFY04448.1 - 0.86 9.0 5.9 0.69 9.3 1.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1654) Peptidase_C50 PF03568.12 KFY04449.1 - 2.9e-116 388.3 0.0 4.2e-116 387.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 KFY04449.1 - 7e-07 29.1 3.2 2.7e-05 24.0 0.2 6.5 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 KFY04449.1 - 0.0092 15.8 10.8 6.8 6.8 0.1 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 KFY04449.1 - 2.4 7.9 4.8 29 4.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat RRM_1 PF00076.17 KFY04455.1 - 3.6e-08 32.9 0.0 5.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFY04455.1 - 3.7e-07 29.8 0.0 5.8e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY04455.1 - 8.5e-05 22.4 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Transket_pyr PF02779.19 KFY04456.1 - 7.1e-47 159.1 0.0 1.1e-46 158.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KFY04456.1 - 2.5e-35 121.1 0.0 7.4e-35 119.5 0.0 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain Sterol_MT_C PF08498.5 KFY04456.1 - 4.4e-20 71.4 0.0 9e-20 70.4 0.0 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 KFY04456.1 - 7.8e-18 64.7 0.0 1.9e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY04456.1 - 2.8e-16 59.4 0.0 7.3e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KFY04456.1 - 3.2e-12 46.0 0.1 5.2e-12 45.4 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KFY04456.1 - 5e-12 45.8 0.0 1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY04456.1 - 5.5e-12 45.9 0.0 1.3e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY04456.1 - 1.9e-11 44.5 0.0 5.3e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY04456.1 - 1.2e-09 38.4 0.0 3.1e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFY04456.1 - 8e-09 34.9 0.0 4.1e-08 32.6 0.0 2.1 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KFY04456.1 - 3.6e-08 33.4 0.0 1.3e-07 31.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFY04456.1 - 6.4e-05 22.4 0.0 0.00013 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KFY04456.1 - 0.00013 21.6 0.1 0.00027 20.5 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 KFY04456.1 - 0.0006 19.4 0.1 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 KFY04456.1 - 0.00061 19.0 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 KFY04456.1 - 0.015 14.4 2.4 0.023 13.9 0.0 2.2 2 0 0 2 2 2 0 O-methyltransferase Methyltransf_24 PF13578.1 KFY04456.1 - 0.019 15.8 0.0 0.076 13.8 0.0 2.0 2 0 0 2 2 1 0 Methyltransferase domain RrnaAD PF00398.15 KFY04456.1 - 0.027 13.4 0.0 0.048 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Aminotran_5 PF00266.14 KFY04456.1 - 0.094 11.4 0.0 0.35 9.5 0.0 1.9 3 0 0 3 3 3 0 Aminotransferase class-V MetW PF07021.7 KFY04456.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW DUF972 PF06156.8 KFY04456.1 - 0.15 12.4 0.6 0.39 11.0 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF972) HECT PF00632.20 KFY04461.1 - 5.9e-97 324.6 0.0 1.1e-96 323.7 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4414 PF14377.1 KFY04461.1 - 2.6e-28 98.0 6.3 2.6e-28 98.0 4.4 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) DUF913 PF06025.7 KFY04461.1 - 3.7e-18 65.4 0.0 3.7e-18 65.4 0.0 3.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) SAPS PF04499.10 KFY04461.1 - 0.054 12.1 0.0 0.054 12.1 0.0 3.5 3 0 0 3 3 3 0 SIT4 phosphatase-associated protein Fringe PF02434.11 KFY04462.1 - 0.00016 20.9 0.1 0.0031 16.7 0.3 2.7 2 1 0 2 2 2 1 Fringe-like PAN_4 PF14295.1 KFY04462.1 - 0.0092 15.6 1.0 0.021 14.5 0.7 1.5 1 0 0 1 1 1 1 PAN domain WD40 PF00400.27 KFY04463.1 - 2.6e-08 33.4 10.3 2.5e-06 27.1 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat PPTA PF01239.17 KFY04464.1 - 4.7e-28 95.3 16.1 3.8e-07 29.1 0.0 5.7 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Ctf8 PF09696.5 KFY04465.1 - 1.5e-36 124.8 0.0 1.8e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Ctf8 Ribosomal_S6e PF01092.14 KFY04466.1 - 5.8e-63 210.2 0.4 1.3e-62 209.0 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e Pribosyltran_N PF13793.1 KFY04467.1 - 1.3e-42 144.2 0.7 7.7e-42 141.6 0.0 2.3 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KFY04467.1 - 3.6e-42 144.1 2.1 1.3e-33 116.3 0.9 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KFY04467.1 - 6.7e-13 48.4 1.0 3.2e-12 46.2 0.4 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KFY04467.1 - 0.0014 17.8 0.2 0.0023 17.1 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF218 PF02698.12 KFY04467.1 - 0.08 12.4 0.1 0.59 9.6 0.1 2.2 1 1 0 1 1 1 0 DUF218 domain His_Phos_1 PF00300.17 KFY04467.1 - 0.13 12.3 0.1 14 5.7 0.0 2.3 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) DUF1674 PF07896.7 KFY04468.1 - 1.4e-15 57.2 3.9 1.4e-15 57.2 2.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1674) MSA_2 PF00985.12 KFY04468.1 - 0.047 13.8 2.6 0.055 13.5 1.8 1.1 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family HpaP PF09483.5 KFY04468.1 - 0.073 13.0 4.5 0.093 12.6 3.1 1.1 1 0 0 1 1 1 0 Type III secretion protein (HpaP) DUF1220 PF06758.8 KFY04468.1 - 0.25 11.1 1.2 0.39 10.5 0.3 1.7 1 1 1 2 2 2 0 Repeat of unknown function (DUF1220) Trp_syntA PF00290.15 KFY04469.1 - 3.9e-91 304.1 0.3 6.6e-91 303.4 0.0 1.4 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.20 KFY04469.1 - 1.6e-46 158.9 1.1 2.4e-46 158.3 0.8 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PcrB PF01884.12 KFY04469.1 - 0.063 12.5 0.2 5.5 6.1 0.0 2.2 2 0 0 2 2 2 0 PcrB family AAA PF00004.24 KFY04470.1 - 2e-15 57.1 0.0 3.5e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KFY04470.1 - 0.0007 20.4 0.9 0.13 13.1 0.0 3.4 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.1 KFY04470.1 - 0.00084 19.3 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFY04470.1 - 0.0017 18.4 0.1 0.018 15.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 KFY04470.1 - 0.0048 16.6 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Zot PF05707.7 KFY04470.1 - 0.019 14.4 0.0 1.3 8.5 0.0 2.4 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) AAA_5 PF07728.9 KFY04470.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 KFY04470.1 - 0.047 13.9 0.0 14 6.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KFY04470.1 - 0.068 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 KFY04470.1 - 0.099 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain GSHPx PF00255.14 KFY04471.1 - 4.4e-39 132.1 0.0 5.6e-39 131.8 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 KFY04471.1 - 0.04 13.5 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 AhpC/TSA family DLH PF01738.13 KFY04472.1 - 3.9e-28 98.2 0.0 7.1e-28 97.3 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KFY04472.1 - 2.4e-06 27.3 0.0 3.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFY04472.1 - 0.00094 19.1 0.1 0.0031 17.4 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KFY04472.1 - 0.12 11.5 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family MFS_1 PF07690.11 KFY04473.1 - 4.6e-32 111.0 26.2 6.8e-25 87.5 7.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY04473.1 - 2.4e-06 26.4 3.4 2.4e-06 26.4 2.4 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter NatB_MDM20 PF09797.4 KFY04476.1 - 3e-51 174.2 0.0 6.5e-51 173.1 0.0 1.5 1 1 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TerY-C PF15616.1 KFY04476.1 - 3.1 7.7 7.8 0.067 13.1 0.3 1.9 3 0 0 3 3 3 0 TerY-C metal binding domain Ilm1 PF10311.4 KFY04477.1 - 9.3e-44 148.8 0.2 1.1e-43 148.6 0.1 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Peptidase_M20 PF01546.23 KFY04478.1 - 4.9e-24 84.8 0.4 8e-24 84.1 0.3 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KFY04478.1 - 3.1e-21 75.1 0.0 5e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KFY04478.1 - 0.007 16.1 0.1 0.015 15.0 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 HAD PF12710.2 KFY04479.1 - 7.5e-09 36.0 0.0 1.3e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Prenyltrans PF00432.16 KFY04480.1 - 6.8e-35 118.3 5.3 2.8e-08 33.1 0.1 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KFY04480.1 - 1.6e-24 86.4 0.0 4.1e-13 49.7 0.0 4.3 2 1 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KFY04480.1 - 3.1e-08 33.5 0.1 0.0072 16.3 0.0 4.1 2 1 2 4 4 4 3 Prenyltransferase-like ThiF PF00899.16 KFY04481.1 - 2.8e-42 143.7 0.0 4.7e-42 143.0 0.0 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 KFY04481.1 - 1.4e-22 79.0 1.1 2.7e-21 74.9 0.7 2.4 1 1 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 KFY04481.1 - 4.7e-13 49.4 0.0 8.7e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 KFY04481.1 - 0.00031 20.8 0.1 0.0051 16.9 0.1 2.3 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 KFY04481.1 - 0.24 10.4 1.0 0.35 9.8 0.7 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 KFY04481.1 - 0.25 10.1 1.1 0.4 9.4 0.8 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pam17 PF08566.5 KFY04482.1 - 2.9e-66 222.4 0.0 4e-66 221.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 EVI2A PF05399.6 KFY04482.1 - 0.3 10.3 6.6 0.48 9.6 4.6 1.2 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Ribonuclease_3 PF00636.21 KFY04483.1 - 1.2e-39 135.2 0.1 7.4e-20 71.5 0.0 2.9 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KFY04483.1 - 1.6e-25 89.5 0.1 3.2e-11 43.3 0.0 3.7 3 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.9 KFY04483.1 - 1.4e-23 82.4 0.0 3.7e-23 81.1 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.24 KFY04483.1 - 1.1e-18 67.2 0.0 2.1e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFY04483.1 - 5.2e-14 51.8 0.0 1.3e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFY04483.1 - 2.8e-11 43.6 0.0 1.2e-10 41.5 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KFY04483.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Piwi PF02171.12 KFY04484.1 - 2.6e-73 246.6 0.0 4.1e-73 245.9 0.0 1.3 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KFY04484.1 - 7.8e-12 44.3 0.1 1.7e-11 43.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 KFY04484.1 - 2.6e-11 42.9 0.0 6.6e-11 41.6 0.0 1.6 2 0 0 2 2 2 1 PAZ domain AAA_27 PF13514.1 KFY04484.1 - 0.21 9.2 0.1 0.3 8.7 0.1 1.1 1 0 0 1 1 1 0 AAA domain ADH_N PF08240.7 KFY04485.1 - 6.5e-09 35.5 1.2 9.9e-08 31.7 0.1 2.7 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFY04485.1 - 2.8e-08 33.3 0.1 5.7e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2448 PF10476.4 KFY04485.1 - 0.15 11.5 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) NAD_Gly3P_dh_N PF01210.18 KFY04486.1 - 1e-43 148.7 0.0 2e-43 147.8 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 KFY04486.1 - 1.7e-43 147.8 0.0 2.5e-43 147.3 0.0 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 KFY04486.1 - 0.044 14.2 0.0 4.6 7.7 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 KFY04486.1 - 0.056 13.7 0.0 2 8.7 0.0 2.4 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PEP_mutase PF13714.1 KFY04487.1 - 8.6e-56 188.8 0.0 1e-55 188.5 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase QRPTase_C PF01729.14 KFY04487.1 - 0.013 15.0 0.1 0.026 14.0 0.0 1.6 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain CAP PF00188.21 KFY04488.1 - 9.7e-20 71.3 3.2 1.4e-19 70.7 2.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Glyco_transf_20 PF00982.16 KFY04489.1 - 3e-162 540.3 0.4 4e-162 539.9 0.3 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KFY04489.1 - 2e-39 134.9 0.0 3.4e-39 134.1 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.6 KFY04489.1 - 0.036 13.5 0.2 0.065 12.7 0.2 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain DUF718 PF05336.8 KFY04489.1 - 0.12 12.1 4.6 1.4 8.7 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF718) WD40 PF00400.27 KFY04490.1 - 2.1e-82 268.3 26.8 2.7e-15 55.5 0.8 8.6 8 1 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 KFY04490.1 - 2.5e-07 30.5 0.1 0.067 12.9 0.0 4.0 2 2 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KFY04490.1 - 8.9e-07 27.4 3.7 0.0017 16.5 0.1 3.4 1 1 1 3 3 3 3 Nucleoporin Nup120/160 NLE PF08154.7 KFY04490.1 - 0.00016 21.6 0.0 0.00028 20.8 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Gmad1 PF10647.4 KFY04490.1 - 0.00042 19.7 0.0 0.42 9.9 0.0 2.4 2 0 0 2 2 2 2 Lipoprotein LpqB beta-propeller domain FAD_binding_9 PF08021.6 KFY04490.1 - 0.03 14.2 0.0 6.9 6.6 0.0 2.7 2 1 0 2 2 2 0 Siderophore-interacting FAD-binding domain PD40 PF07676.7 KFY04490.1 - 0.51 10.0 3.2 1.3e+02 2.4 0.1 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 KFY04490.1 - 3.3 7.1 4.1 20 4.6 0.0 3.5 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature MutS_V PF00488.16 KFY04491.1 - 1.1e-62 211.5 1.4 4.7e-60 202.9 0.9 2.3 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KFY04491.1 - 1e-31 110.3 1.2 1e-31 110.3 0.9 1.8 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 KFY04491.1 - 7.3e-09 35.6 1.8 1.3e-08 34.8 0.2 2.3 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 KFY04491.1 - 1.6e-08 34.7 0.1 5.4e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 MutS domain II AAA_29 PF13555.1 KFY04491.1 - 0.15 11.5 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Vpu PF00558.14 KFY04491.1 - 1.9 8.1 7.4 1.1 8.9 1.5 2.7 2 1 1 3 3 3 0 Vpu protein G-patch PF01585.18 KFY04492.1 - 4.3e-06 26.4 0.0 2e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 G-patch domain DUF936 PF06075.7 KFY04492.1 - 0.001 18.0 30.0 0.0013 17.7 20.8 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF936) Utp14 PF04615.8 KFY04492.1 - 0.071 11.2 43.2 0.0074 14.5 27.2 1.2 2 0 0 2 2 2 0 Utp14 protein Mitofilin PF09731.4 KFY04492.1 - 0.28 9.7 31.6 0.43 9.1 21.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Hex_IIIa PF02455.11 KFY04492.1 - 1.3 7.5 16.2 1.7 7.2 11.2 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) PemK PF02452.12 KFY04497.1 - 1e-05 25.7 0.0 3e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 PemK-like protein OTT_1508_deam PF14441.1 KFY04498.1 - 5.1e-11 42.5 0.0 1.2e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase Vitellogenin_N PF01347.17 KFY04498.1 - 0.03 12.5 0.1 0.045 11.9 0.1 1.2 1 0 0 1 1 1 0 Lipoprotein amino terminal region Mucin PF01456.12 KFY04501.1 - 0.0042 16.8 0.0 0.0048 16.6 0.0 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein 2OG-FeII_Oxy_3 PF13640.1 KFY04502.1 - 5.6e-09 36.4 0.0 1.3e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KFY04502.1 - 9.2e-05 22.0 0.0 0.00023 20.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DAO PF01266.19 KFY04503.1 - 2.3e-48 164.9 1.0 1.1e-47 162.6 0.7 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFY04503.1 - 1.4e-06 28.1 0.1 3.2e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KFY04503.1 - 0.0013 17.4 0.1 0.0019 16.9 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.12 KFY04503.1 - 0.0021 17.2 0.2 0.0035 16.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KFY04503.1 - 0.0047 17.3 0.0 0.013 15.8 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFY04503.1 - 0.014 15.2 0.1 0.54 10.0 0.0 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KFY04503.1 - 0.031 14.0 0.1 0.066 12.9 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding GMC_oxred_N PF00732.14 KFY04503.1 - 0.12 11.4 0.0 2.2 7.3 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase DUF2014 PF09427.5 KFY04504.1 - 7.3e-83 277.6 1.4 1.4e-82 276.7 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) Sterol-sensing PF12349.3 KFY04504.1 - 5.7e-27 94.0 4.5 5.7e-27 94.0 3.1 1.7 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation HLH PF00010.21 KFY04504.1 - 1.7e-13 50.0 1.3 2.1e-13 49.7 0.1 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Patched PF02460.13 KFY04504.1 - 0.0005 18.1 3.1 0.0008 17.4 2.1 1.2 1 0 0 1 1 1 1 Patched family WD40 PF00400.27 KFY04504.1 - 0.016 15.0 0.1 0.91 9.5 0.0 2.9 2 0 0 2 2 2 0 WD domain, G-beta repeat Sugar_tr PF00083.19 KFY04505.1 - 2.4e-43 148.3 16.1 3.2e-43 147.9 11.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY04505.1 - 1.2e-32 112.9 29.9 2.2e-32 112.1 20.7 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.3 KFY04505.1 - 1.4e-05 23.7 21.1 0.00074 18.1 5.9 2.4 1 1 1 2 2 2 2 Vacuole effluxer Atg22 like DBD_Tnp_Hermes PF10683.4 KFY04505.1 - 0.042 13.3 0.1 0.088 12.2 0.1 1.4 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain TFIIA PF03153.8 KFY04507.1 - 0.045 13.6 9.3 0.06 13.2 6.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit bZIP_1 PF00170.16 KFY04507.1 - 0.17 11.8 7.6 0.33 10.9 5.2 1.5 1 0 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.10 KFY04507.1 - 0.64 9.8 5.6 1.2 9.0 3.9 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Bul1_N PF04425.7 KFY04508.1 - 6.8e-08 31.5 0.4 0.001 17.6 0.9 2.4 2 1 1 3 3 3 2 Bul1 N terminus Bul1_C PF04426.7 KFY04508.1 - 4e-05 22.9 0.0 5.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Bul1 C terminus FAD_binding_3 PF01494.14 KFY04509.1 - 3.6e-12 46.0 0.1 1e-07 31.3 0.0 2.6 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KFY04509.1 - 0.00026 20.0 0.1 0.00045 19.2 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFY04509.1 - 0.00041 20.3 0.1 0.00092 19.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFY04509.1 - 0.0085 15.9 0.1 0.014 15.2 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KFY04509.1 - 0.064 13.6 0.1 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Aldo_ket_red PF00248.16 KFY04510.1 - 6e-72 241.8 0.0 6.8e-72 241.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sugarporin_N PF11471.3 KFY04510.1 - 0.039 13.6 0.0 0.068 12.8 0.0 1.4 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension FAD_binding_3 PF01494.14 KFY04511.1 - 4.3e-36 124.7 0.0 1.2e-35 123.2 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 KFY04511.1 - 0.013 14.4 0.0 2 7.2 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein ThiF PF00899.16 KFY04511.1 - 0.084 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 ThiF family Glyoxalase PF00903.20 KFY04512.1 - 2.5e-11 43.6 2.4 5.8e-10 39.2 1.3 2.5 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KFY04512.1 - 1.6e-08 35.1 0.2 0.0022 18.5 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KFY04512.1 - 0.00065 19.6 0.1 0.0027 17.7 0.1 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAA_hydrolase PF01557.13 KFY04513.1 - 1.7e-48 164.9 0.0 3.8e-48 163.8 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans PF04082.13 KFY04513.1 - 5e-16 58.3 1.1 8.1e-16 57.6 0.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 KFY04513.1 - 1.7e-06 28.0 3.8 1.7e-06 28.0 2.6 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KFY04513.1 - 5.3e-05 23.2 13.5 0.043 14.1 1.0 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KFY04513.1 - 0.00054 20.1 22.6 0.015 15.5 3.0 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KFY04513.1 - 0.077 13.1 9.8 1.9 8.7 2.4 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.10 KFY04513.1 - 0.09 12.2 1.6 0.71 9.3 0.0 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain TRI12 PF06609.8 KFY04514.1 - 1.5e-26 92.8 11.0 1.9e-26 92.4 7.6 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KFY04514.1 - 1.8e-22 79.5 41.2 2.4e-19 69.2 25.7 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily YtpI PF14007.1 KFY04514.1 - 0.33 10.8 0.0 0.33 10.8 0.0 3.2 3 0 0 3 3 3 0 YtpI-like protein Ank_2 PF12796.2 KFY04515.1 - 2.8e-29 101.2 1.3 5.8e-09 36.1 0.0 3.7 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFY04515.1 - 9.6e-26 88.2 4.9 8.3e-06 25.3 0.0 6.9 6 1 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 KFY04515.1 - 2.8e-19 67.2 2.6 0.053 13.7 0.0 8.0 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 KFY04515.1 - 3.3e-19 68.8 3.5 9.7e-06 25.9 0.0 5.0 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY04515.1 - 5.2e-17 61.4 3.9 0.00025 21.1 0.1 4.7 4 0 0 4 4 4 3 Ankyrin repeats (many copies) PQ-loop PF04193.9 KFY04516.1 - 0.00022 20.6 1.6 0.00022 20.6 1.1 2.9 3 0 0 3 3 3 1 PQ loop repeat MtN3_slv PF03083.11 KFY04516.1 - 0.0083 15.9 3.6 0.027 14.3 0.3 2.7 2 1 0 2 2 2 1 Sugar efflux transporter for intercellular exchange DUF3533 PF12051.3 KFY04516.1 - 0.0089 14.8 2.7 0.013 14.2 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF2157 PF09925.4 KFY04516.1 - 0.24 11.0 10.0 0.019 14.5 3.3 2.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) RGS PF00615.14 KFY04517.1 - 3e-11 43.4 0.0 4.7e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Gag_spuma PF03276.9 KFY04518.1 - 2.4 6.4 7.7 3.6 5.8 5.4 1.3 1 0 0 1 1 1 0 Spumavirus gag protein DUF3295 PF11702.3 KFY04521.1 - 6.3e-92 309.1 42.4 1.1e-91 308.3 29.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3295) APH PF01636.18 KFY04524.1 - 7.1e-19 68.4 0.0 1.3e-18 67.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family APH PF01636.18 KFY04525.1 - 4.1e-21 75.8 0.0 5.9e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family TPR_10 PF13374.1 KFY04526.1 - 4.6e-59 194.8 7.8 2.7e-11 43.0 0.0 7.8 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.1 KFY04526.1 - 2.2e-49 165.3 8.6 6.7e-15 54.7 0.3 4.8 3 1 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 KFY04526.1 - 7.4e-16 57.5 0.2 0.00033 20.2 0.0 4.7 4 0 0 4 4 4 3 TPR repeat TPR_2 PF07719.12 KFY04526.1 - 1.1e-15 56.2 5.1 0.058 13.3 0.4 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 KFY04526.1 - 9.8e-15 53.1 4.3 0.074 12.8 0.0 6.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 KFY04526.1 - 2.5e-13 48.9 4.0 0.054 13.1 0.2 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 KFY04526.1 - 1.1e-10 41.8 6.9 0.00081 19.9 1.2 6.3 3 1 2 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.9 KFY04526.1 - 5.1e-09 35.7 0.7 0.53 10.8 0.3 6.7 7 0 0 7 7 6 1 Tetratricopeptide repeat NB-ARC PF00931.17 KFY04526.1 - 4.7e-08 32.2 0.0 1.2e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 NB-ARC domain TPR_17 PF13431.1 KFY04526.1 - 7.3e-08 32.0 0.5 13 6.2 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_19 PF14559.1 KFY04526.1 - 1.8e-06 28.1 3.7 1.2 9.5 0.2 6.2 3 1 3 6 6 6 3 Tetratricopeptide repeat AAA_22 PF13401.1 KFY04526.1 - 2.3e-05 24.5 0.0 0.00045 20.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain TPR_5 PF12688.2 KFY04526.1 - 6.2e-05 23.0 2.7 0.0024 17.8 0.0 3.3 1 1 1 3 3 3 1 Tetratrico peptide repeat TPR_8 PF13181.1 KFY04526.1 - 0.00032 20.2 2.4 55 3.8 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 KFY04526.1 - 0.00035 20.9 16.6 2 9.3 0.8 7.8 6 2 2 8 8 7 1 Tetratricopeptide repeat AAA_16 PF13191.1 KFY04526.1 - 0.0028 17.6 0.1 0.016 15.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF676 PF05057.9 KFY04526.1 - 0.042 13.1 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative serine esterase (DUF676) AAA_25 PF13481.1 KFY04526.1 - 0.045 13.1 0.1 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Atu4866 PF11512.3 KFY04526.1 - 0.24 11.1 6.7 58 3.5 0.0 4.4 3 1 1 4 4 4 0 Agrobacterium tumefaciens protein Atu4866 Sugar_tr PF00083.19 KFY04527.1 - 2e-73 247.5 34.4 2.4e-73 247.2 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY04527.1 - 2.5e-21 75.7 59.5 7.7e-21 74.1 26.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 KFY04527.1 - 0.0045 15.1 5.4 0.011 13.8 1.5 2.3 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family CbtB PF09489.5 KFY04527.1 - 1.8 8.5 8.5 6.7 6.7 0.1 3.9 4 0 0 4 4 4 0 Probable cobalt transporter subunit (CbtB) p450 PF00067.17 KFY04528.1 - 9.1e-61 205.7 0.0 1.2e-60 205.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Chromo PF00385.19 KFY04532.1 - 0.0001 21.9 0.2 0.00019 21.0 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF3827 PF12877.2 KFY04532.1 - 0.14 10.2 3.5 0.17 9.9 2.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) CRAL_TRIO PF00650.15 KFY04533.1 - 5.1e-27 94.3 0.0 7.3e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KFY04533.1 - 3.1e-12 46.4 0.5 9e-12 44.9 0.3 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain AIF_C PF14721.1 KFY04533.1 - 0.0034 17.6 0.4 0.011 16.0 0.1 2.0 1 1 1 2 2 2 1 Apoptosis-inducing factor, mitochondrion-associated, C-term Rad4 PF03835.10 KFY04534.1 - 2.3e-31 108.1 0.3 2.3e-31 108.1 0.2 2.2 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KFY04534.1 - 4.5e-28 96.7 0.1 9.4e-28 95.7 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 KFY04534.1 - 6.6e-18 63.9 0.1 2.5e-17 62.1 0.1 2.1 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KFY04534.1 - 3.1e-15 56.2 0.2 3.1e-15 56.2 0.1 3.3 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 CorA PF01544.13 KFY04534.1 - 6.1e-14 51.7 4.9 2.2e-11 43.3 0.6 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Transglut_core PF01841.14 KFY04534.1 - 0.019 15.1 0.0 0.067 13.4 0.0 1.9 1 0 0 1 1 1 0 Transglutaminase-like superfamily Kelch_1 PF01344.20 KFY04534.1 - 0.17 11.4 0.2 0.49 9.9 0.2 1.8 1 0 0 1 1 1 0 Kelch motif UPF0104 PF03706.8 KFY04534.1 - 0.79 8.9 0.6 1.2 8.2 0.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) zf-AN1 PF01428.11 KFY04535.1 - 8.3e-24 83.1 18.9 2.2e-12 46.6 4.3 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 KFY04535.1 - 0.00011 22.0 14.6 0.00062 19.5 2.0 2.4 2 0 0 2 2 2 2 IBR domain Transp_Tc5_C PF04236.10 KFY04535.1 - 0.17 12.1 12.6 0.7 10.1 0.9 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zf-PHD-like PF15446.1 KFY04535.1 - 0.37 10.0 6.7 4.8 6.4 0.1 2.3 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain HIT PF01230.18 KFY04536.1 - 1.6e-13 51.0 0.0 4.7e-13 49.5 0.0 1.8 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KFY04536.1 - 0.0038 17.4 0.1 0.025 14.8 0.0 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KFY04536.1 - 0.0093 15.6 0.8 0.038 13.6 0.0 2.1 2 1 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 ATP_transf PF09830.4 KFY04536.1 - 0.14 12.0 0.2 18 5.1 0.0 3.1 2 1 1 3 3 3 0 ATP adenylyltransferase DUF2611 PF11022.3 KFY04537.1 - 4e-25 87.6 0.0 4.6e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) Glyco_hydro_2 PF00703.16 KFY04540.1 - 2.2e-12 47.4 1.4 4.9e-12 46.2 0.0 2.4 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 KFY04540.1 - 6.9e-09 35.4 0.1 1.3e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 KFY04540.1 - 0.00046 19.1 0.0 0.00079 18.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Zn_clus PF00172.13 KFY04541.1 - 1e-06 28.5 6.9 2.2e-06 27.4 4.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FixP_N PF14715.1 KFY04541.1 - 0.3 10.5 0.1 0.3 10.5 0.0 1.8 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Glyco_hydro_3 PF00933.16 KFY04542.1 - 2.3e-42 145.0 0.0 2.7e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain DUF1343 PF07075.6 KFY04543.1 - 1.4e-126 422.2 0.0 1.6e-126 422.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1343) MFS_1 PF07690.11 KFY04544.1 - 4.7e-28 97.9 20.8 4.7e-28 97.9 14.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UPF0075 PF03702.9 KFY04545.1 - 1e-75 254.9 0.0 1.2e-75 254.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) Ank_2 PF12796.2 KFY04546.1 - 1.3e-51 172.9 2.3 3e-12 46.7 0.1 5.5 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFY04546.1 - 3.3e-43 143.4 1.0 0.00025 20.6 0.0 9.5 10 0 0 10 10 10 9 Ankyrin repeat Ank_5 PF13857.1 KFY04546.1 - 1.7e-38 129.7 4.4 1.4e-06 28.3 0.0 9.2 3 2 6 9 9 9 8 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFY04546.1 - 4e-37 125.9 0.2 6.6e-07 29.6 0.0 6.8 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY04546.1 - 1.6e-35 117.5 0.0 0.0066 16.5 0.0 9.4 9 0 0 9 9 9 9 Ankyrin repeat DUF2384 PF09722.5 KFY04546.1 - 0.022 14.5 0.5 16 5.4 0.0 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF2384) Sugar_tr PF00083.19 KFY04552.1 - 5.7e-87 292.1 25.8 6.7e-87 291.9 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY04552.1 - 4.5e-27 94.6 30.9 3.9e-22 78.4 6.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFY04552.1 - 2.8 6.2 33.9 0.031 12.6 5.4 3.6 2 2 2 4 4 4 0 MFS/sugar transport protein Glyco_hydro_28 PF00295.12 KFY04553.1 - 1.7e-38 132.3 8.3 4e-38 131.1 5.7 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Adeno_PIX PF03955.9 KFY04553.1 - 0.04 14.4 0.0 0.1 13.1 0.0 1.6 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) Pectate_lyase_3 PF12708.2 KFY04553.1 - 1.4 9.0 16.5 21 5.1 10.7 3.1 1 1 0 1 1 1 0 Pectate lyase superfamily protein Pectinesterase PF01095.14 KFY04554.1 - 6e-43 146.5 10.0 7.7e-43 146.1 7.0 1.0 1 0 0 1 1 1 1 Pectinesterase Glyco_hydro_28 PF00295.12 KFY04555.1 - 3.9e-40 137.7 6.6 4.9e-40 137.4 4.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_43 PF04616.9 KFY04556.1 - 6.7e-76 255.0 0.0 9e-76 254.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Fungal_trans PF04082.13 KFY04557.1 - 5e-17 61.6 0.3 8e-17 60.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.8 KFY04558.1 - 1.2e-35 123.0 0.0 1.6e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KFY04558.1 - 3.2e-13 49.0 0.0 3.8e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 KFY04558.1 - 5.1e-07 29.1 0.0 0.00094 18.4 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFY04558.1 - 0.00055 19.7 0.0 0.0013 18.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFY04558.1 - 0.0006 19.7 0.0 0.0012 18.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KFY04558.1 - 0.0022 16.8 0.0 0.44 9.1 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family BAAT_C PF08840.6 KFY04558.1 - 0.037 13.7 0.0 0.058 13.0 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 KFY04558.1 - 0.19 10.1 0.0 0.3 9.5 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) ZZ PF00569.12 KFY04563.1 - 0.54 9.8 5.6 1 8.9 3.9 1.4 1 0 0 1 1 1 0 Zinc finger, ZZ type Peptidase_C12 PF01088.16 KFY04564.1 - 1e-53 181.6 0.0 1.3e-53 181.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 PALP PF00291.20 KFY04565.1 - 8.1e-75 251.8 0.7 1e-74 251.5 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 KFY04565.1 - 3.5e-43 145.1 0.0 3.2e-22 77.9 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HIG_1_N PF04588.8 KFY04566.1 - 1.2e-23 82.5 0.0 1.8e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF1491 PF07372.7 KFY04566.1 - 0.012 15.5 1.4 0.022 14.6 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1491) TUSC2 PF15000.1 KFY04566.1 - 0.055 13.5 5.3 0.54 10.3 0.2 2.9 1 1 2 3 3 3 0 Tumour suppressor candidate 2 Trypan_PARP PF05887.6 KFY04567.1 - 0.013 15.3 12.2 0.013 15.3 8.5 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) VWA_2 PF13519.1 KFY04570.1 - 0.00028 21.0 0.0 0.00038 20.6 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KFY04570.1 - 0.033 13.9 0.0 0.11 12.2 0.0 1.8 1 1 0 1 1 1 0 von Willebrand factor type A domain Acyl-CoA_dh_M PF02770.14 KFY04571.1 - 6.7e-06 25.5 0.0 1.4e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KFY04571.1 - 0.017 15.2 0.0 0.042 13.9 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain F-box PF00646.28 KFY04572.1 - 0.021 14.4 0.7 0.052 13.2 0.1 2.0 2 0 0 2 2 2 0 F-box domain F-box-like_2 PF13013.1 KFY04572.1 - 0.023 14.3 0.0 0.072 12.8 0.0 1.9 1 1 0 1 1 1 0 F-box-like domain Sugar_tr PF00083.19 KFY04575.1 - 2.5e-81 273.5 35.0 2.8e-81 273.4 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY04575.1 - 4e-30 104.7 54.8 8.6e-25 87.1 21.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY04576.1 - 5.8e-58 196.5 15.8 8.5e-58 195.9 10.9 1.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY04576.1 - 3.2e-12 45.8 27.9 2.8e-10 39.4 18.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1614 PF07758.6 KFY04576.1 - 0.0067 16.1 0.8 0.025 14.3 0.6 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF1614) Gate PF07670.9 KFY04576.1 - 3.7 7.4 11.6 1.4 8.8 5.5 2.3 2 0 0 2 2 2 0 Nucleoside recognition Histidinol_dh PF00815.15 KFY04577.1 - 4.8e-118 394.3 3.3 6e-118 394.0 2.3 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Zn_clus PF00172.13 KFY04578.1 - 2.4e-06 27.3 9.4 4.2e-06 26.5 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFY04578.1 - 4.2e-06 25.8 0.6 8.2e-06 24.8 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rad1 PF02144.11 KFY04581.1 - 2.7e-83 278.9 1.3 3.5e-83 278.5 0.9 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Bromodomain PF00439.20 KFY04582.1 - 6e-26 90.1 0.5 1.2e-25 89.2 0.3 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 KFY04582.1 - 1.9e-09 37.5 0.1 4.8e-09 36.2 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFY04582.1 - 4.9e-09 36.0 0.2 1.1e-08 34.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KFY04582.1 - 0.17 11.6 0.0 0.34 10.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein ABC_membrane_2 PF06472.10 KFY04583.1 - 1.9e-95 319.2 1.8 2.2e-93 312.4 0.2 2.5 3 0 0 3 3 3 2 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KFY04583.1 - 3.3e-14 53.3 0.0 9.3e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 KFY04583.1 - 0.08 12.4 0.0 0.41 10.2 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain PEPCK_ATP PF01293.15 KFY04585.1 - 1.2e-215 716.3 0.0 1.5e-215 716.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 KFY04585.1 - 0.081 13.2 0.1 21 5.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KFY04585.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 KFY04588.1 - 3.8e-45 153.4 0.0 7.4e-45 152.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KFY04588.1 - 1.3e-26 91.8 0.0 3e-26 90.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KFY04588.1 - 1.5e-21 76.0 0.0 4.9e-21 74.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KFY04588.1 - 0.053 12.3 0.0 0.1 11.3 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain DEAD PF00270.24 KFY04589.1 - 1.4e-45 154.8 0.0 2.6e-45 153.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBP10CT PF08147.7 KFY04589.1 - 2.9e-24 84.6 3.7 7.9e-24 83.2 2.6 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 KFY04589.1 - 6.9e-21 73.8 0.0 7.6e-20 70.5 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Fungal_trans PF04082.13 KFY04592.1 - 1.6e-07 30.4 1.2 3.1e-07 29.5 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY04592.1 - 3.4e-06 26.8 8.8 3.4e-06 26.8 6.1 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAM-associated PF14303.1 KFY04592.1 - 0.11 12.8 4.1 0.21 11.8 2.8 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Ank_2 PF12796.2 KFY04595.1 - 2.7e-15 56.4 0.0 4.2e-07 30.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFY04595.1 - 9.7e-13 48.2 0.0 7e-05 23.2 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY04595.1 - 5.6e-12 45.4 0.3 8.3e-05 22.7 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY04595.1 - 2.5e-09 36.4 0.0 0.025 14.7 0.0 4.2 4 1 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 KFY04595.1 - 1.9e-05 24.2 0.0 1.4 8.8 0.0 4.0 5 0 0 5 5 5 2 Ankyrin repeat KaiC PF06745.8 KFY04595.1 - 0.0064 15.6 0.0 1.5 7.9 0.0 2.2 1 1 1 2 2 2 2 KaiC Tricorn_C1 PF14684.1 KFY04595.1 - 0.02 14.7 0.1 3.9 7.4 0.0 2.2 2 0 0 2 2 2 0 Tricorn protease C1 domain TPD52 PF04201.10 KFY04596.1 - 0.0048 16.6 1.3 0.0071 16.0 0.9 1.3 1 0 0 1 1 1 1 Tumour protein D52 family WD40_alt PF14077.1 KFY04596.1 - 0.13 11.9 0.3 0.29 10.7 0.2 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif IncA PF04156.9 KFY04596.1 - 0.25 10.9 3.8 0.43 10.1 2.6 1.5 1 1 0 1 1 1 0 IncA protein Zn_clus PF00172.13 KFY04602.1 - 0.00042 20.1 13.1 0.00089 19.1 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 KFY04602.1 - 0.066 12.4 0.0 0.066 12.4 0.0 3.1 3 0 0 3 3 3 0 Histone chaperone domain CHZ Ribosomal_S7e PF01251.13 KFY04607.1 - 5e-37 127.2 0.0 5.4e-37 127.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Abhydrolase_6 PF12697.2 KFY04610.1 - 4.2e-22 79.1 0.0 4.8e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY04610.1 - 1.2e-15 57.7 0.0 5.1e-10 39.3 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFY04610.1 - 1e-09 38.3 0.0 2.4e-09 37.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KFY04610.1 - 0.001 17.6 0.0 0.0033 15.9 0.0 2.0 1 1 0 1 1 1 1 Ndr family DLH PF01738.13 KFY04610.1 - 0.045 13.0 0.0 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 KFY04610.1 - 0.071 12.5 0.0 5.9 6.2 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Caps_synth PF05704.7 KFY04611.1 - 3.1e-12 46.2 0.0 6e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 KFY04611.1 - 7.9e-05 22.9 0.0 0.00013 22.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif NmrA PF05368.8 KFY04612.1 - 1.3e-26 93.3 0.0 1.9e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFY04612.1 - 0.02 14.9 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 KFY04612.1 - 0.056 12.1 0.0 0.093 11.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family tRNA-synt_1c PF00749.16 KFY04614.1 - 1.6e-68 230.7 0.0 3e-42 144.4 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KFY04614.1 - 2.6e-27 95.5 0.0 6.7e-27 94.2 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain HTH_Tnp_Tc3_1 PF11427.3 KFY04614.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Tc3 transposase LacAB_rpiB PF02502.13 KFY04618.1 - 1.5e-43 147.7 0.2 1.8e-43 147.5 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.1 KFY04618.1 - 0.048 13.5 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 Glycine-rich SFCGS Fungal_trans PF04082.13 KFY04619.1 - 1.4e-28 99.5 0.0 5.1e-27 94.3 0.0 2.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain tRNA-synt_2b PF00587.20 KFY04619.1 - 8.1e-23 80.8 0.0 1.6e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KFY04619.1 - 9.7e-10 38.4 0.5 3.2e-09 36.7 0.3 2.0 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DIL PF01843.14 KFY04620.1 - 6.6e-21 74.1 0.9 1.2e-12 47.6 0.2 2.5 2 0 0 2 2 2 2 DIL domain Ank_2 PF12796.2 KFY04620.1 - 1.5e-15 57.2 0.0 3.5e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFY04620.1 - 1.2e-14 53.3 0.0 2.1e-05 24.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KFY04620.1 - 3.3e-11 43.0 0.0 8e-07 29.1 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFY04620.1 - 9.3e-11 41.9 0.0 1.1e-05 25.7 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY04620.1 - 8e-07 28.7 0.0 0.3 11.4 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat P_C PF06640.6 KFY04620.1 - 0.0019 18.2 0.7 0.0019 18.2 0.5 1.7 2 0 0 2 2 2 1 P protein C-terminus COesterase PF00135.23 KFY04621.1 - 8.8e-80 268.9 0.0 1.4e-79 268.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Zn_clus PF00172.13 KFY04621.1 - 7.9e-09 35.2 9.3 1.2e-08 34.6 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.8 KFY04621.1 - 1.9e-07 30.9 0.1 1.3e-06 28.1 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Fungal_trans_2 PF11951.3 KFY04621.1 - 0.0011 17.6 0.0 0.0017 17.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2424 PF10340.4 KFY04621.1 - 0.026 13.1 0.1 1.4 7.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 KFY04621.1 - 0.057 12.6 0.2 0.1 11.7 0.2 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Oxidored_FMN PF00724.15 KFY04622.1 - 5.9e-90 301.6 0.0 6.8e-90 301.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 KFY04622.1 - 0.062 12.5 0.0 1.6 7.9 0.0 2.7 1 1 1 3 3 3 0 Xylose isomerase-like TIM barrel Peptidase_M76 PF09768.4 KFY04623.1 - 0.084 12.3 0.1 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase M76 family Myosin_tail_1 PF01576.14 KFY04624.1 - 0.025 12.3 3.2 0.07 10.8 0.1 2.3 2 0 0 2 2 2 0 Myosin tail DMPK_coil PF08826.5 KFY04624.1 - 0.6 10.0 6.1 0.23 11.3 0.9 2.6 3 0 0 3 3 3 0 DMPK coiled coil domain like Med4 PF10018.4 KFY04624.1 - 1.2 8.5 5.5 0.31 10.4 0.1 2.3 2 1 1 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 CP12 PF02672.10 KFY04624.1 - 1.4 9.4 6.5 21 5.6 0.6 3.0 3 0 0 3 3 3 0 CP12 domain M PF02370.11 KFY04624.1 - 2.6 8.7 8.7 0.1 13.0 1.2 2.6 2 0 0 2 2 2 0 M protein repeat TMF_DNA_bd PF12329.3 KFY04624.1 - 6.5 6.6 8.9 0.18 11.6 1.3 2.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF3425 PF11905.3 KFY04625.1 - 7.2e-20 71.2 0.7 1.3e-19 70.4 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Cytochrom_B561 PF03188.11 KFY04625.1 - 6.4e-16 58.4 6.2 1.4e-15 57.3 4.3 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 bZIP_1 PF00170.16 KFY04625.1 - 0.0016 18.3 5.1 0.003 17.4 3.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor PepSY_TM_2 PF13703.1 KFY04625.1 - 0.029 14.5 8.0 1.6 8.9 0.0 3.7 2 1 0 2 2 2 0 PepSY-associated TM helix DUF418 PF04235.7 KFY04625.1 - 0.25 11.0 10.8 0.043 13.5 3.4 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF418) Ni_hydr_CYTB PF01292.15 KFY04625.1 - 0.37 10.1 10.3 5.7 6.2 7.1 2.3 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF4231 PF14015.1 KFY04625.1 - 8.5 6.4 14.5 3.2 7.7 0.4 4.5 3 2 0 3 3 3 0 Protein of unknown function (DUF4231) DUF4267 PF14087.1 KFY04626.1 - 4.8e-06 26.1 0.7 7.7e-06 25.4 0.5 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4267) Dynamin_N PF00350.18 KFY04629.1 - 1.5e-32 112.7 0.1 3e-32 111.7 0.1 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KFY04629.1 - 3e-14 52.4 0.0 7e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 KFY04629.1 - 3.9e-05 23.5 0.2 0.00035 20.4 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KFY04629.1 - 0.0012 19.3 0.0 0.0036 17.8 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 KFY04629.1 - 0.022 14.0 0.9 3.6 6.8 0.1 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B DUF3273 PF11677.3 KFY04629.1 - 0.25 10.5 0.0 0.38 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3273) Sugar_tr PF00083.19 KFY04630.1 - 3.2e-94 316.0 23.2 1.2e-63 215.2 7.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFY04630.1 - 1.9e-17 63.0 32.2 4.1e-10 38.9 4.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KFY04630.1 - 0.096 12.7 7.1 0.26 11.3 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) CytB6-F_Fe-S PF08802.5 KFY04630.1 - 7.7 6.6 6.5 15 5.7 1.1 3.0 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit Dak2 PF02734.12 KFY04631.1 - 2.2e-38 131.6 0.6 8.6e-38 129.7 0.0 2.2 3 0 0 3 3 3 1 DAK2 domain DUF2090 PF09863.4 KFY04631.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) Dak1 PF02733.12 KFY04632.1 - 3.2e-86 288.8 0.1 4e-86 288.5 0.1 1.0 1 0 0 1 1 1 1 Dak1 domain adh_short_C2 PF13561.1 KFY04633.1 - 5.3e-26 91.8 0.0 7e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KFY04633.1 - 3.8e-23 82.2 1.2 5e-23 81.8 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFY04633.1 - 1.1e-12 48.0 0.3 1.5e-12 47.5 0.2 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KFY04633.1 - 0.054 13.4 0.1 0.68 9.9 0.1 2.1 1 1 0 1 1 1 0 NADH(P)-binding BEX PF04538.7 KFY04633.1 - 0.18 12.0 0.1 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Brain expressed X-linked like family rve PF00665.21 KFY04635.1 - 1.5e-08 34.7 0.0 8.4e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 KFY04635.1 - 0.0043 16.5 0.0 0.011 15.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain NESP55 PF06390.7 KFY04635.1 - 0.13 11.6 5.0 0.2 10.9 3.4 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Trypan_PARP PF05887.6 KFY04635.1 - 1 9.1 21.2 1.4 8.6 6.2 2.2 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Abhydrolase_6 PF12697.2 KFY04636.1 - 3.1e-38 131.9 0.0 3.8e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY04636.1 - 7.2e-29 100.9 0.2 1.1e-14 54.5 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFY04636.1 - 8.4e-24 83.9 0.2 5.3e-23 81.3 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KFY04636.1 - 5.6e-12 45.3 0.4 1.7e-11 43.7 0.1 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 KFY04636.1 - 5.6e-08 32.2 1.4 0.0004 19.6 0.0 2.6 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KFY04636.1 - 0.00017 21.0 0.0 0.00039 19.9 0.0 1.6 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.13 KFY04636.1 - 0.0011 18.2 0.0 0.0027 17.0 0.0 1.6 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF915 PF06028.6 KFY04636.1 - 0.0079 15.3 0.1 0.016 14.2 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Ser_hydrolase PF06821.8 KFY04636.1 - 0.0082 15.7 0.0 0.22 11.1 0.0 2.4 2 1 0 2 2 2 1 Serine hydrolase Abhydrolase_4 PF08386.5 KFY04636.1 - 0.025 14.4 0.0 0.086 12.7 0.0 1.9 2 0 0 2 2 2 0 TAP-like protein UPF0227 PF05728.7 KFY04636.1 - 0.12 12.0 0.0 1.1 9.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) FSH1 PF03959.8 KFY04636.1 - 0.13 11.7 0.2 0.96 8.8 0.0 2.1 1 1 1 2 2 2 0 Serine hydrolase (FSH1) MFS_1 PF07690.11 KFY04639.1 - 1.7e-22 79.6 35.2 1.7e-22 79.6 24.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Beta_elim_lyase PF01212.16 KFY04640.1 - 3.3e-63 213.5 0.0 4e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KFY04640.1 - 0.014 14.4 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Chordopox_RPO7 PF05864.7 KFY04641.1 - 0.16 12.0 0.2 0.79 9.8 0.0 2.0 2 0 0 2 2 2 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) p450 PF00067.17 KFY04642.1 - 3.8e-61 207.0 0.0 5.5e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 KFY04642.1 - 5.2e-10 39.5 0.0 1.5e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFY04642.1 - 4.1e-07 29.8 0.1 1.8e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KFY04642.1 - 0.00049 19.9 0.0 0.0013 18.5 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Saccharop_dh PF03435.13 KFY04642.1 - 0.018 14.0 0.1 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KFY04642.1 - 0.086 12.9 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Aminotran_1_2 PF00155.16 KFY04643.1 - 8.7e-44 149.9 0.0 1.1e-43 149.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.16 KFY04643.1 - 0.14 10.9 0.1 0.95 8.2 0.0 2.1 2 1 0 2 2 2 0 Aminotransferase class-III BNR_2 PF13088.1 KFY04645.1 - 2.1e-06 27.2 0.0 0.00036 19.9 0.0 2.4 2 0 0 2 2 2 2 BNR repeat-like domain BNR PF02012.15 KFY04645.1 - 0.0012 18.3 9.5 0.23 11.4 0.0 4.2 4 0 0 4 4 4 2 BNR/Asp-box repeat Sua5_yciO_yrdC PF01300.13 KFY04646.1 - 2.2e-54 183.3 0.0 3e-54 182.9 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 KFY04646.1 - 7.8e-26 90.6 0.0 2.1e-25 89.1 0.0 1.7 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding Clat_adaptor_s PF01217.15 KFY04647.1 - 1.3e-14 54.1 0.2 1.3e-13 50.9 0.3 1.9 2 0 0 2 2 2 1 Clathrin adaptor complex small chain MCM PF00493.18 KFY04648.1 - 2.4e-140 467.0 0.0 3.3e-140 466.6 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KFY04648.1 - 8.6e-25 87.5 0.1 3.5e-24 85.6 0.0 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KFY04648.1 - 2.7e-06 26.7 0.0 0.00015 20.9 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KFY04648.1 - 2.9e-05 23.8 0.1 0.00012 21.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KFY04648.1 - 0.00042 19.9 0.0 0.0015 18.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zn-ribbon_8 PF09723.5 KFY04648.1 - 0.066 13.1 1.0 0.15 12.0 0.7 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Sigma54_activat PF00158.21 KFY04648.1 - 0.091 12.2 0.2 2.9 7.3 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain Rad21_Rec8_N PF04825.8 KFY04650.1 - 1.1e-38 131.5 0.0 2e-38 130.7 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KFY04650.1 - 1.3e-08 33.8 0.2 4.1e-08 32.2 0.1 1.9 1 1 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KFY04650.1 - 0.0035 16.9 0.0 0.025 14.1 0.0 2.1 2 0 0 2 2 2 1 ScpA/B protein E1-E2_ATPase PF00122.15 KFY04651.1 - 2.9e-71 239.1 0.1 5.2e-71 238.3 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KFY04651.1 - 2.8e-41 141.0 2.9 2.8e-41 141.0 2.0 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KFY04651.1 - 7.2e-29 101.7 0.0 3.2e-28 99.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFY04651.1 - 7.7e-19 66.9 0.0 1.6e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KFY04651.1 - 3.2e-13 50.2 0.0 9.2e-13 48.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFY04651.1 - 4.8e-13 48.8 0.0 1.1e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFY04651.1 - 0.00021 20.9 0.7 0.00021 20.9 0.5 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase YjgP_YjgQ PF03739.9 KFY04651.1 - 0.0058 15.4 0.5 0.72 8.5 0.0 2.3 2 0 0 2 2 2 2 Predicted permease YjgP/YjgQ family zf-HC5HC2H_2 PF13832.1 KFY04654.1 - 1.2e-18 67.0 1.6 1.2e-18 67.0 1.1 4.0 4 0 0 4 4 4 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KFY04654.1 - 2.3e-15 56.4 4.1 2.3e-15 56.4 2.8 4.6 4 1 0 4 4 4 2 PHD-like zinc-binding domain BAH PF01426.13 KFY04654.1 - 1.8e-12 47.0 0.1 3.6e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 KFY04654.1 - 7.8e-12 44.6 54.9 5e-07 29.2 4.8 6.2 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.1 KFY04654.1 - 9.2e-09 34.4 3.8 9.2e-09 34.4 2.6 6.1 7 0 0 7 7 7 2 PHD-finger WD40 PF00400.27 KFY04655.1 - 1.1e-22 79.0 0.0 8e-10 38.2 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 KFY04655.1 - 7e-07 27.7 0.1 0.012 13.8 0.0 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 KFY04655.1 - 0.083 11.9 0.0 6.2 5.8 0.0 2.1 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 KFY04655.1 - 0.098 12.0 0.2 0.56 9.6 0.2 2.0 1 1 0 1 1 1 0 PQQ-like domain Sel1 PF08238.7 KFY04657.1 - 4.4e-14 52.5 7.4 0.0022 18.5 0.2 4.2 4 0 0 4 4 4 3 Sel1 repeat COPIIcoated_ERV PF07970.7 KFY04658.1 - 1.9e-69 233.6 0.1 1e-45 156.1 0.0 2.3 2 0 0 2 2 2 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KFY04658.1 - 1.1e-33 115.0 0.1 7e-33 112.4 0.0 2.0 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sulfate_transp PF00916.15 KFY04659.1 - 9.9e-74 247.8 11.0 2.1e-73 246.7 7.7 1.6 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KFY04659.1 - 1.9e-30 104.3 3.3 1.9e-30 104.3 2.3 2.9 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KFY04659.1 - 1.8e-09 36.9 0.0 3.6e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain VRR_NUC PF08774.6 KFY04660.1 - 4.8e-19 68.2 0.0 9.7e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 VRR-NUC domain PrkA PF06798.7 KFY04660.1 - 0.02 14.1 0.1 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 PrkA serine protein kinase C-terminal domain ChaB PF06150.7 KFY04660.1 - 0.049 13.4 0.0 0.77 9.6 0.0 2.4 2 0 0 2 2 2 0 ChaB Dpy-30 PF05186.8 KFY04661.1 - 6.2e-15 54.4 0.0 8.9e-15 53.8 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif Ribosomal_S13_N PF08069.7 KFY04662.1 - 7.6e-30 102.5 0.0 1.5e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 KFY04662.1 - 5.3e-22 77.3 0.0 8.6e-22 76.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 KFY04662.1 - 0.02 14.6 0.2 0.043 13.5 0.0 1.6 2 1 0 2 2 2 0 'Paired box' domain RabGAP-TBC PF00566.13 KFY04663.1 - 2.5e-31 108.8 0.0 4.2e-26 91.7 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF4072 PF13284.1 KFY04663.1 - 0.27 11.4 1.9 1.8 8.7 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4072) 7tm_2 PF00002.19 KFY04664.1 - 1.6e-05 24.1 17.0 4.6e-05 22.6 11.0 2.0 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) OGG_N PF07934.7 KFY04665.1 - 1.4e-35 121.7 0.0 3.1e-35 120.6 0.0 1.6 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 KFY04665.1 - 2.2e-15 56.8 0.0 3.7e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KFY04665.1 - 0.00015 21.2 0.1 0.00048 19.6 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif SIR2 PF02146.12 KFY04667.1 - 8.3e-28 97.3 0.0 1.9e-09 37.4 0.0 3.2 2 1 1 3 3 3 3 Sir2 family TPP_enzyme_M PF00205.17 KFY04667.1 - 0.081 12.6 0.0 0.3 10.8 0.0 1.9 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Beta-lactamase PF00144.19 KFY04669.1 - 6.1e-27 94.5 1.1 1.4e-26 93.2 0.7 1.5 1 1 0 1 1 1 1 Beta-lactamase PHP PF02811.14 KFY04670.1 - 0.00026 20.8 0.0 0.0004 20.2 0.0 1.2 1 0 0 1 1 1 1 PHP domain MFS_1 PF07690.11 KFY04671.1 - 3.4e-53 180.6 16.7 3.4e-53 180.6 11.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY04671.1 - 3.1e-08 32.6 11.4 3.1e-08 32.6 7.9 3.0 2 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KFY04671.1 - 0.00038 18.7 5.1 0.00076 17.7 3.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 KFY04671.1 - 0.0011 17.7 1.1 0.0011 17.7 0.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF791) OATP PF03137.15 KFY04671.1 - 0.025 12.6 5.7 0.07 11.1 1.7 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family TPR_11 PF13414.1 KFY04672.1 - 5.9e-11 41.8 6.2 3.5e-06 26.5 0.0 5.3 5 1 1 6 6 6 2 TPR repeat TPR_16 PF13432.1 KFY04672.1 - 4.4e-06 27.2 2.1 2.6e-05 24.7 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 KFY04672.1 - 4.2e-05 23.1 10.1 0.012 15.4 0.0 4.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 KFY04672.1 - 8.6e-05 22.8 2.1 3.9 8.3 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 KFY04672.1 - 0.00029 20.7 3.5 0.0028 17.5 0.1 4.0 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KFY04672.1 - 0.00042 20.2 0.6 0.9 9.8 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 KFY04672.1 - 0.00057 19.4 0.9 3.3 7.7 0.0 5.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KFY04672.1 - 0.00091 18.7 0.2 2.4 7.9 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KFY04672.1 - 0.024 14.4 0.3 1 9.3 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.16 KFY04674.1 - 8.2e-85 284.9 0.0 1.6e-84 283.9 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Syntaxin-18_N PF10496.4 KFY04674.1 - 3.2e-17 62.1 0.8 4.4e-16 58.5 0.0 2.8 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus BLOC1_2 PF10046.4 KFY04674.1 - 0.09 12.9 4.8 0.41 10.8 2.8 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Myc_N PF01056.13 KFY04675.1 - 0.015 14.4 0.5 0.015 14.4 0.3 2.0 2 0 0 2 2 2 0 Myc amino-terminal region Y_phosphatase3C PF13348.1 KFY04675.1 - 0.082 13.0 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family C-terminal region DUF883 PF05957.8 KFY04677.1 - 0.013 15.9 2.1 0.013 15.9 1.5 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) ETRAMP PF09716.5 KFY04677.1 - 0.046 13.6 4.1 0.053 13.4 0.5 2.4 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF4366 PF14283.1 KFY04677.1 - 0.13 11.6 10.5 0.061 12.7 1.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) V-SNARE_C PF12352.3 KFY04678.1 - 1.2e-14 54.0 0.1 2.9e-14 52.8 0.1 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KFY04678.1 - 8.6e-05 22.1 0.5 0.0017 18.0 0.0 2.4 2 0 0 2 2 2 1 Sec20 Baculo_PEP_C PF04513.7 KFY04678.1 - 0.046 13.5 2.9 0.11 12.3 1.6 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TarH PF02203.10 KFY04678.1 - 0.52 10.1 5.1 0.87 9.4 3.5 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue TPK_catalytic PF04263.11 KFY04679.1 - 1.5e-24 85.9 0.0 2.1e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 KFY04679.1 - 3.6e-22 77.8 0.0 5.6e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Hydrolase PF00702.21 KFY04680.1 - 5.3e-23 82.5 0.0 3.2e-22 80.0 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFY04680.1 - 3.5e-19 69.7 0.0 7e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFY04680.1 - 1.9e-18 66.3 0.0 6.1e-18 64.7 0.0 1.9 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KFY04680.1 - 2e-06 27.6 0.1 1e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFY04680.1 - 0.0074 15.8 0.1 0.036 13.6 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FixQ PF05545.6 KFY04680.1 - 0.61 9.7 4.6 12 5.6 0.7 2.6 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF4139 PF13598.1 KFY04681.1 - 2.2e-57 194.7 6.8 6.8e-40 137.3 0.0 3.4 3 1 0 3 3 3 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 KFY04681.1 - 6.9e-11 42.5 0.1 6.9e-11 42.5 0.1 3.6 1 1 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) 2-oxoacid_dh PF00198.18 KFY04682.1 - 2.6e-75 252.6 0.0 3.3e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KFY04682.1 - 3.4e-17 61.8 3.9 4.1e-17 61.5 0.8 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 KFY04682.1 - 2.6e-14 52.5 0.3 7.2e-14 51.1 0.2 1.8 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.3 KFY04682.1 - 0.042 14.1 0.1 0.2 11.9 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3614) Sec7 PF01369.15 KFY04683.1 - 7.1e-65 218.2 0.3 3.6e-64 215.9 0.1 2.3 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 KFY04683.1 - 4.3e-51 172.6 4.4 4.3e-51 172.6 3.0 2.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KFY04683.1 - 6e-30 102.6 3.2 4.3e-29 99.8 0.1 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) NAD_binding_7 PF13241.1 KFY04684.1 - 3.1e-33 114.0 0.1 4.6e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KFY04684.1 - 9.5e-23 79.3 0.0 1.5e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KFY04684.1 - 1.2e-11 43.3 0.0 2.2e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.1 KFY04684.1 - 0.0055 16.7 0.1 0.009 16.0 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF3386 PF11866.3 KFY04684.1 - 0.019 14.1 0.0 1.1 8.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3386) Shikimate_DH PF01488.15 KFY04684.1 - 0.023 14.7 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.16 KFY04684.1 - 0.053 13.0 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase FYVE PF01363.16 KFY04685.1 - 1e-20 73.3 29.7 1e-15 57.3 5.7 2.9 3 0 0 3 3 3 2 FYVE zinc finger zf-Di19 PF05605.7 KFY04685.1 - 0.00014 21.8 5.5 0.013 15.5 0.0 2.8 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.11 KFY04685.1 - 0.00018 21.3 3.2 0.00018 21.3 2.2 3.8 5 1 0 5 5 5 2 AN1-like Zinc finger Rbsn PF11464.3 KFY04685.1 - 0.0082 15.6 0.0 0.027 14.0 0.0 1.8 1 0 0 1 1 1 1 Rabenosyn Rab binding domain Flagellin_N PF00669.15 KFY04685.1 - 0.22 11.2 3.8 6.6 6.5 0.0 2.8 3 0 0 3 3 3 0 Bacterial flagellin N-terminal helical region CK_II_beta PF01214.13 KFY04685.1 - 6.6 6.1 9.3 0.32 10.4 1.2 2.7 3 1 0 3 3 3 0 Casein kinase II regulatory subunit Peroxin-13_N PF04088.8 KFY04687.1 - 1.5e-48 164.7 0.2 2.3e-48 164.1 0.1 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region Microvir_H PF04687.7 KFY04687.1 - 0.17 10.9 0.5 0.23 10.4 0.3 1.2 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) GST_N_3 PF13417.1 KFY04688.1 - 1.3e-09 38.1 0.0 2.4e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KFY04688.1 - 1.1e-08 34.8 0.0 2.5e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KFY04688.1 - 3.7e-08 33.2 0.0 5.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KFY04688.1 - 7e-08 32.5 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 KFY04688.1 - 0.00033 20.6 0.2 0.0031 17.4 0.0 2.5 3 0 0 3 3 3 1 Glutaredoxin GST_C_2 PF13410.1 KFY04688.1 - 0.00094 19.0 0.0 0.0024 17.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain COesterase PF00135.23 KFY04689.1 - 1.9e-89 300.7 0.0 2.7e-89 300.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Acetyltransf_3 PF13302.1 KFY04689.1 - 1.1e-32 113.0 0.0 3.2e-32 111.6 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KFY04689.1 - 0.00024 21.0 0.3 0.00065 19.6 0.2 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KFY04689.1 - 0.0011 19.0 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Abhydrolase_3 PF07859.8 KFY04689.1 - 0.0063 16.1 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold FR47 PF08445.5 KFY04689.1 - 0.021 14.5 0.0 0.059 13.1 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.1 KFY04689.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HMG-CoA_red PF00368.13 KFY04690.1 - 8e-156 518.3 4.0 1e-155 518.0 2.8 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 KFY04690.1 - 4.8e-46 156.2 0.0 1.1e-45 155.0 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 KFY04690.1 - 1.5e-12 47.1 8.3 1.9e-11 43.6 5.8 2.3 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KFY04690.1 - 1.5e-07 29.7 1.8 2.6e-07 28.9 1.2 1.3 1 0 0 1 1 1 1 Patched family SNARE PF05739.14 KFY04693.1 - 2.9e-17 62.1 2.3 4.6e-17 61.4 0.2 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 KFY04693.1 - 5e-15 55.5 1.0 5e-15 55.5 0.7 2.7 3 0 0 3 3 3 1 Syntaxin MCPsignal PF00015.16 KFY04693.1 - 0.0046 16.5 8.3 0.033 13.7 0.1 2.9 2 1 1 3 3 3 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Sed5p PF11416.3 KFY04693.1 - 0.0066 15.8 0.1 0.013 14.8 0.1 1.6 1 0 0 1 1 1 1 Integral membrane protein Sed5p NPV_P10 PF05531.7 KFY04693.1 - 0.17 12.1 8.0 4.5 7.6 0.1 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.6 KFY04693.1 - 1.8 9.0 6.6 1.9 8.9 0.1 3.3 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Spc7 PF08317.6 KFY04693.1 - 3.5 6.1 7.6 0.19 10.3 0.8 2.0 3 0 0 3 3 3 0 Spc7 kinetochore protein DEAD PF00270.24 KFY04694.1 - 2.1e-39 134.7 0.0 3.5e-39 134.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KFY04694.1 - 4.6e-19 68.0 1.0 7.6e-19 67.3 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KFY04694.1 - 1.9e-05 23.5 0.0 2.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain SecA_DEAD PF07517.9 KFY04694.1 - 0.12 11.6 0.1 2.7 7.2 0.0 2.3 2 0 0 2 2 2 0 SecA DEAD-like domain CMS1 PF14617.1 KFY04694.1 - 0.14 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit RecR PF02132.10 KFY04698.1 - 0.00061 19.1 0.8 0.0011 18.2 0.6 1.4 1 0 0 1 1 1 1 RecR protein OCD_Mu_crystall PF02423.10 KFY04699.1 - 3.8e-11 42.3 0.6 7.4e-07 28.2 0.1 2.4 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Glyco_hydro_42M PF08532.5 KFY04699.1 - 0.037 13.1 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain Aldo_ket_red PF00248.16 KFY04700.1 - 4.9e-65 219.1 0.0 8.7e-65 218.3 0.0 1.4 1 0 0 1 1 1 1 Aldo/keto reductase family GMC_oxred_N PF00732.14 KFY04700.1 - 2.2e-55 187.9 0.0 3.1e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFY04700.1 - 3.3e-31 108.5 0.0 6.6e-31 107.5 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KFY04700.1 - 7.2e-05 21.8 0.3 0.0046 15.9 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KFY04700.1 - 0.00015 21.7 0.0 0.00058 19.8 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFY04700.1 - 0.00029 20.0 0.5 0.0047 16.0 0.1 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 KFY04700.1 - 0.00053 18.9 0.0 0.092 11.5 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KFY04700.1 - 0.0066 15.4 0.1 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 KFY04700.1 - 0.099 11.0 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Zn_clus PF00172.13 KFY04701.1 - 0.00013 21.7 10.8 0.00013 21.7 7.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.21 KFY04702.1 - 9.5e-22 76.9 0.3 2.4e-21 75.6 0.2 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DAO PF01266.19 KFY04702.1 - 5.7e-17 61.6 0.1 8.8e-17 61.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase ADH_N PF08240.7 KFY04702.1 - 4e-10 39.4 0.0 1e-09 38.1 0.0 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Herpes_UL21 PF03252.8 KFY04702.1 - 0.06 11.8 0.0 0.086 11.2 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL21 PTR2 PF00854.16 KFY04703.1 - 1.2e-27 96.7 2.2 1.5e-24 86.5 1.5 2.4 1 1 0 1 1 1 1 POT family NLPC_P60 PF00877.14 KFY04704.1 - 6.1e-22 77.4 0.1 1.4e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 NlpC/P60 family SH3_3 PF08239.6 KFY04704.1 - 0.00026 21.1 0.4 0.0013 18.8 0.0 2.4 3 0 0 3 3 3 1 Bacterial SH3 domain DUF830 PF05708.7 KFY04704.1 - 0.042 13.8 0.0 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 Orthopoxvirus protein of unknown function (DUF830) Abhydrolase_6 PF12697.2 KFY04705.1 - 4.5e-25 88.8 0.0 9.5e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY04705.1 - 4.1e-22 78.8 0.0 5.3e-21 75.2 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFY04705.1 - 2.2e-12 46.9 0.0 8.7e-12 45.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Zn_clus PF00172.13 KFY04705.1 - 0.0046 16.8 2.6 0.0076 16.1 1.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_4 PF08386.5 KFY04705.1 - 0.0047 16.7 0.0 0.016 15.0 0.0 1.9 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 KFY04705.1 - 0.02 14.7 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Esterase PF00756.15 KFY04705.1 - 0.067 12.6 0.0 0.13 11.7 0.0 1.5 1 1 0 1 1 1 0 Putative esterase BTV_NS2 PF04514.7 KFY04705.1 - 0.21 10.4 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FA_hydroxylase PF04116.8 KFY04707.1 - 5.5e-12 46.0 16.3 5.5e-12 46.0 11.3 2.4 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Phenol_monoox PF04663.7 KFY04707.1 - 0.012 15.2 0.4 0.032 13.9 0.2 1.7 1 0 0 1 1 1 0 Phenol hydroxylase conserved region AATF-Che1 PF13339.1 KFY04708.1 - 0.04 14.0 0.4 0.04 14.0 0.2 1.9 3 0 0 3 3 3 0 Apoptosis antagonizing transcription factor Alph_Pro_TM PF09608.5 KFY04709.1 - 0.015 14.8 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) Fumble PF03630.9 KFY04710.1 - 6e-133 442.9 0.0 1.2e-131 438.6 0.0 2.1 1 1 0 1 1 1 1 Fumble RhaA PF06134.6 KFY04710.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 L-rhamnose isomerase (RhaA) GATase_6 PF13522.1 KFY04711.1 - 3.8e-13 49.5 0.3 5.9e-13 48.9 0.2 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KFY04711.1 - 2.9e-09 36.0 0.1 4.3e-08 32.1 0.1 2.0 2 0 0 2 2 2 1 Glutamine amidotransferases class-II GATase_2 PF00310.16 KFY04711.1 - 2.5e-06 26.4 0.6 3.3e-06 26.0 0.4 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_7 PF13537.1 KFY04711.1 - 0.0021 17.7 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain WD40 PF00400.27 KFY04715.1 - 1.9e-06 27.5 0.2 0.1 12.4 0.0 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat PhyH PF05721.8 KFY04716.1 - 2.3e-05 24.5 0.0 3.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) F-box-like PF12937.2 KFY04717.1 - 0.006 16.2 0.7 0.015 15.0 0.5 1.7 1 0 0 1 1 1 1 F-box-like BDHCT PF08072.6 KFY04717.1 - 0.0079 16.2 1.7 0.23 11.6 0.0 2.4 2 0 0 2 2 2 1 BDHCT (NUC031) domain F-box PF00646.28 KFY04717.1 - 0.21 11.2 1.5 1.3 8.7 0.2 2.6 2 0 0 2 2 2 0 F-box domain Rpp20 PF12328.3 KFY04722.1 - 0.042 13.4 0.7 0.046 13.3 0.5 1.1 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Zn_clus PF00172.13 KFY04723.1 - 3.9e-08 33.0 8.1 3.9e-08 33.0 5.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.1 KFY04724.1 - 2.2e-30 106.0 0.0 2.6e-30 105.8 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFY04724.1 - 0.00011 21.5 0.0 0.00015 21.0 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 KFY04724.1 - 0.00045 19.7 0.0 0.00078 18.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TraD PF06412.6 KFY04724.1 - 0.13 11.9 0.1 0.22 11.1 0.1 1.3 1 0 0 1 1 1 0 Conjugal transfer protein TraD ABC_tran PF00005.22 KFY04725.1 - 1e-46 158.6 0.1 1.2e-24 87.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KFY04725.1 - 1.3e-23 84.4 1.9 1.1e-05 25.5 0.0 4.3 4 0 0 4 4 4 4 AAA domain ABC2_membrane_3 PF12698.2 KFY04725.1 - 1.4e-21 76.9 45.3 1.6e-15 56.9 15.7 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.1 KFY04725.1 - 1.9e-10 40.0 2.0 3.9e-05 23.0 0.5 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KFY04725.1 - 1.7e-08 35.0 2.9 0.0021 18.4 0.1 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KFY04725.1 - 8.1e-08 31.7 3.1 0.081 12.1 0.2 3.8 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 KFY04725.1 - 5e-05 22.5 1.0 0.085 12.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KFY04725.1 - 0.00017 21.6 1.5 0.34 10.8 0.3 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.1 KFY04725.1 - 0.00028 20.0 0.0 1.1 8.2 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain Zeta_toxin PF06414.7 KFY04725.1 - 0.00084 18.4 0.3 0.44 9.6 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin AAA_22 PF13401.1 KFY04725.1 - 0.0028 17.8 0.1 0.61 10.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KFY04725.1 - 0.0063 15.9 0.1 1.7 7.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFY04725.1 - 0.0065 16.1 0.5 3.8 7.3 0.1 3.2 2 0 0 2 2 2 1 Part of AAA domain MutS_V PF00488.16 KFY04725.1 - 0.0095 15.3 0.1 0.69 9.2 0.0 2.5 2 0 0 2 2 2 1 MutS domain V AAA_30 PF13604.1 KFY04725.1 - 0.023 14.2 3.0 2.4 7.7 0.3 2.8 2 1 1 3 3 3 0 AAA domain SbcCD_C PF13558.1 KFY04725.1 - 0.046 13.6 0.5 8.4 6.3 0.0 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Miro PF08477.8 KFY04725.1 - 0.057 13.9 0.0 4 7.9 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein SRP54 PF00448.17 KFY04725.1 - 0.069 12.5 0.7 9.4 5.6 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_33 PF13671.1 KFY04725.1 - 0.071 12.9 0.3 9.3 6.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KFY04725.1 - 0.071 13.0 1.7 2.7 7.9 0.5 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KFY04725.1 - 0.1 12.0 1.6 5.4 6.3 0.4 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_14 PF13173.1 KFY04725.1 - 0.19 11.5 0.1 14 5.5 0.0 2.8 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KFY04725.1 - 0.22 10.9 1.3 0.62 9.4 0.3 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF4162 PF13732.1 KFY04725.1 - 0.27 11.7 0.0 0.66 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) NB-ARC PF00931.17 KFY04725.1 - 0.63 8.8 0.4 11 4.7 0.2 2.2 2 0 0 2 2 2 0 NB-ARC domain Mg_chelatase PF01078.16 KFY04725.1 - 1.3 8.1 6.1 18 4.4 0.3 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AA_permease_2 PF13520.1 KFY04726.1 - 2.1e-40 138.5 41.3 4.5e-40 137.4 28.6 1.5 1 1 0 1 1 1 1 Amino acid permease SWIM PF04434.12 KFY04727.1 - 0.14 11.6 0.3 0.32 10.5 0.2 1.5 1 0 0 1 1 1 0 SWIM zinc finger TFCD_C PF12612.3 KFY04728.1 - 2e-26 92.6 0.0 7.5e-26 90.7 0.0 2.0 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 KFY04728.1 - 0.0015 18.4 6.0 0.33 11.1 0.0 5.8 5 0 0 5 5 5 1 HEAT repeat RestrictionMunI PF11407.3 KFY04728.1 - 0.084 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II restriction enzyme MunI HEAT_EZ PF13513.1 KFY04728.1 - 0.093 13.2 0.2 0.093 13.2 0.1 6.2 6 1 1 7 7 7 0 HEAT-like repeat PAN_4 PF14295.1 KFY04729.1 - 0.0017 18.0 0.4 0.0056 16.3 0.3 1.9 1 1 0 1 1 1 1 PAN domain SSP160 PF06933.6 KFY04729.1 - 0.0066 14.4 4.9 0.0092 14.0 3.4 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 DUF1628 PF07790.6 KFY04729.1 - 0.023 15.4 0.1 0.061 14.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) Alpha_GJ PF03229.8 KFY04729.1 - 0.042 14.1 6.3 0.085 13.2 4.3 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J SpoIIIAH PF12685.2 KFY04729.1 - 0.053 13.0 0.0 0.063 12.7 0.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Acetyltransf_1 PF00583.19 KFY04730.1 - 2.5e-09 37.0 0.0 3.3e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KFY04730.1 - 2.4e-07 30.8 0.0 3.7e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KFY04730.1 - 5.8e-06 26.4 0.1 1.8e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KFY04730.1 - 0.0012 18.6 0.0 0.019 14.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KFY04730.1 - 0.031 14.0 0.0 0.072 12.8 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein UPF0167 PF03691.9 KFY04730.1 - 0.15 11.4 0.1 0.27 10.6 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0167) Pkinase PF00069.20 KFY04731.1 - 2.7e-22 79.1 0.0 3.6e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY04731.1 - 5.2e-18 65.0 0.0 7.2e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFY04731.1 - 0.0055 15.7 0.0 0.0079 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFY04731.1 - 0.026 14.2 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KFY04731.1 - 0.065 12.1 0.0 0.22 10.4 0.0 1.7 1 1 0 1 1 1 0 Kinase-like RIO1 PF01163.17 KFY04731.1 - 0.094 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Ank_2 PF12796.2 KFY04737.1 - 2.4e-16 59.8 2.6 1.4e-08 34.9 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KFY04737.1 - 2.3e-10 39.7 1.6 0.00096 18.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KFY04737.1 - 1.5e-07 31.7 0.2 0.005 17.3 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY04737.1 - 0.0029 17.7 0.3 0.88 9.9 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) NMO PF03060.10 KFY04742.1 - 7.3e-42 143.6 3.1 9.2e-42 143.3 2.1 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KFY04742.1 - 0.0049 15.7 0.0 0.0072 15.2 0.0 1.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ECH PF00378.15 KFY04743.1 - 1.2e-47 162.1 0.0 1.6e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KFY04743.1 - 0.001 18.8 0.1 0.0075 16.0 0.0 2.3 2 1 1 3 3 3 1 Peptidase family S49 Ank_2 PF12796.2 KFY04744.1 - 3e-64 213.3 6.6 7.6e-21 74.2 0.1 6.0 3 1 3 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 KFY04744.1 - 1.2e-55 182.6 22.0 8.3e-08 31.6 0.0 11.9 11 2 0 11 11 11 11 Ankyrin repeat Ank_4 PF13637.1 KFY04744.1 - 1.8e-49 165.2 5.7 2.5e-09 37.3 0.0 8.7 6 2 4 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY04744.1 - 4.3e-41 134.8 14.7 1.8e-06 27.6 0.0 11.4 11 1 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.1 KFY04744.1 - 2.3e-35 119.8 12.6 1.2e-07 31.7 0.3 8.1 6 3 3 9 9 9 8 Ankyrin repeats (many copies) Methyltransf_10 PF05971.7 KFY04745.1 - 1.6e-59 201.5 0.0 2.3e-59 200.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 KFY04745.1 - 0.00012 22.0 0.0 0.00029 20.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY04745.1 - 0.00062 20.3 0.0 0.0013 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFY04745.1 - 0.00082 18.7 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 KFY04745.1 - 0.032 13.8 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PrmA PF06325.8 KFY04745.1 - 0.056 12.5 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) E1-E2_ATPase PF00122.15 KFY04747.1 - 1.2e-62 210.9 6.5 3e-62 209.6 4.5 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFY04747.1 - 2.6e-23 83.5 0.0 4.8e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KFY04747.1 - 4.9e-13 49.6 0.0 1.3e-12 48.3 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KFY04747.1 - 2.2e-12 46.2 0.0 4.9e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KFY04747.1 - 0.0016 18.0 0.1 0.0032 17.0 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KFY04747.1 - 0.021 14.7 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Nop14 PF04147.7 KFY04747.1 - 0.35 8.7 7.0 0.49 8.2 4.9 1.1 1 0 0 1 1 1 0 Nop14-like family Prothymosin PF03247.9 KFY04747.1 - 0.44 10.7 12.5 0.79 9.8 8.6 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family Daxx PF03344.10 KFY04747.1 - 5.4 5.3 9.2 8.1 4.7 6.3 1.2 1 0 0 1 1 1 0 Daxx Family DUF4267 PF14087.1 KFY04752.1 - 4.3e-17 61.7 1.7 5.2e-17 61.4 1.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF4345 PF14248.1 KFY04752.1 - 0.01 15.2 3.0 0.015 14.7 2.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4345) Hydrophobin_2 PF06766.6 KFY04753.1 - 1.6e-19 69.3 8.5 1.9e-19 69.0 5.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin eIF3_N PF09440.5 KFY04754.1 - 5.2e-49 165.8 3.5 1.2e-48 164.6 2.4 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 KFY04754.1 - 1.4e-13 51.0 0.2 3.6e-13 49.7 0.1 1.8 1 0 0 1 1 1 1 PCI domain DUF718 PF05336.8 KFY04754.1 - 0.0021 17.8 0.1 0.005 16.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF718) VPR PF00522.13 KFY04754.1 - 0.063 13.0 0.3 0.6 9.9 0.0 2.7 3 0 0 3 3 3 0 VPR/VPX protein Img2 PF05046.9 KFY04755.1 - 1.2e-22 79.9 0.2 1.8e-22 79.3 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) ARID PF01388.16 KFY04756.1 - 4.4e-20 71.3 0.0 4.4e-20 71.3 0.0 2.6 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain EVE PF01878.13 KFY04758.1 - 7.2e-06 26.0 0.9 1.6e-05 24.9 0.0 1.9 2 1 0 2 2 2 1 EVE domain SRP-alpha_N PF04086.8 KFY04758.1 - 7.6 5.8 14.0 9 5.5 9.7 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Asp-B-Hydro_N PF05279.6 KFY04758.1 - 8.3 6.1 12.1 10 5.8 8.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SPX PF03105.14 KFY04759.1 - 1.6e-14 54.3 0.0 2.1e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 SPX domain Pox_A_type_inc PF04508.7 KFY04759.1 - 0.087 12.6 0.5 0.087 12.6 0.3 2.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Fic PF02661.13 KFY04760.1 - 2.6e-14 53.6 0.0 1.4e-13 51.3 0.0 2.1 1 1 0 1 1 1 1 Fic/DOC family DUF2382 PF09557.5 KFY04760.1 - 0.052 13.4 0.2 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2382) Ald_Xan_dh_C2 PF02738.13 KFY04761.1 - 1.7e-192 640.6 1.0 2.4e-192 640.1 0.7 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 KFY04761.1 - 1.1e-47 161.6 0.0 2.5e-47 160.4 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 KFY04761.1 - 6.8e-33 112.6 0.2 2.6e-32 110.8 0.0 2.1 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 KFY04761.1 - 1.7e-29 102.1 0.0 4.5e-29 100.7 0.0 1.8 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 KFY04761.1 - 7.3e-29 99.4 0.1 1.5e-28 98.4 0.1 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 KFY04761.1 - 3.7e-08 33.0 0.2 2e-07 30.6 0.0 2.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain adh_short PF00106.20 KFY04762.1 - 8.4e-18 64.8 0.1 1.3e-17 64.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFY04762.1 - 6.5e-09 35.7 0.1 1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KFY04762.1 - 0.00013 21.8 0.0 0.00022 21.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KFY04762.1 - 0.00035 20.0 0.0 0.00056 19.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFY04762.1 - 0.0062 16.5 0.0 0.0093 15.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding TIR-like PF10137.4 KFY04762.1 - 0.096 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain DUF3425 PF11905.3 KFY04763.1 - 9.8e-26 90.2 0.1 3.4e-25 88.5 0.0 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3425) AflR PF08493.5 KFY04764.1 - 1.1e-15 57.4 1.6 2.1e-15 56.4 1.1 1.5 1 0 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.13 KFY04764.1 - 2.4e-07 30.5 8.2 5e-07 29.5 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactamase_B PF00753.22 KFY04766.1 - 2.4e-21 76.2 0.2 3.1e-21 75.9 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KFY04766.1 - 1.4e-05 24.7 0.1 2.3e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain tRNA-synt_2b PF00587.20 KFY04766.1 - 0.0075 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Lactamase_B_3 PF13483.1 KFY04766.1 - 0.0091 15.7 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain ketoacyl-synt PF00109.21 KFY04767.1 - 2.4e-71 240.1 0.0 1.8e-70 237.3 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KFY04767.1 - 4.9e-50 170.6 0.0 9.8e-50 169.6 0.0 1.5 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KFY04767.1 - 2.2e-32 111.3 0.8 5.9e-32 110.0 0.6 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 KFY04767.1 - 5e-08 33.0 1.1 1.3e-07 31.7 0.8 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 KFY04767.1 - 5.3e-06 25.6 0.1 1.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain BBE PF08031.7 KFY04768.1 - 0.0012 18.6 0.1 0.0028 17.5 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 KFY04768.1 - 0.098 12.1 0.1 0.39 10.1 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Pec_lyase_C PF00544.14 KFY04769.1 - 1.8e-41 141.8 9.6 2.8e-41 141.2 6.6 1.3 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KFY04769.1 - 0.00024 20.9 11.7 0.00045 19.9 7.3 1.9 1 1 1 2 2 2 2 Right handed beta helix region Ribonuclease_T2 PF00445.13 KFY04770.1 - 5.1e-46 156.6 0.1 1.1e-45 155.5 0.1 1.5 1 0 0 1 1 1 1 Ribonuclease T2 family AAA_2 PF07724.9 KFY04770.1 - 4.9e-06 26.5 0.0 7.7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) HET PF06985.6 KFY04771.1 - 6.3e-21 74.9 8.4 1.2e-17 64.3 0.3 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Rxt3 PF08642.5 KFY04772.1 - 5.6e-28 97.5 0.0 2e-27 95.7 0.0 2.0 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 KFY04772.1 - 4.8e-05 23.2 0.0 0.00064 19.6 0.0 2.2 2 0 0 2 2 2 1 LCCL domain Ycf1 PF05758.7 KFY04772.1 - 6.4 4.3 4.6 9.4 3.7 3.2 1.2 1 0 0 1 1 1 0 Ycf1 CLN3 PF02487.12 KFY04773.1 - 9.3e-103 344.1 10.5 2.8e-101 339.2 7.3 2.2 1 1 0 1 1 1 1 CLN3 protein Dynactin PF12455.3 KFY04773.1 - 2e-90 302.4 7.7 2e-90 302.4 5.4 2.4 2 1 0 2 2 2 1 Dynein associated protein CAP_GLY PF01302.20 KFY04773.1 - 3e-21 74.8 0.3 5.5e-21 74.0 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain Aa_trans PF01490.13 KFY04774.1 - 6.5e-52 176.3 39.5 7.9e-52 176.0 27.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ATG27 PF09451.5 KFY04774.1 - 0.18 10.9 1.0 0.31 10.2 0.7 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 Herpes_UL87 PF03043.9 KFY04776.1 - 1.6 7.0 17.4 2.4 6.4 12.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL87 family 6PF2K PF01591.13 KFY04777.1 - 5.2e-82 274.2 0.1 6.6e-82 273.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KFY04777.1 - 1.3e-29 103.3 0.0 2.3e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KFY04777.1 - 8e-07 29.0 0.0 1.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KFY04777.1 - 3e-05 23.3 0.0 4.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 KFY04777.1 - 0.00035 21.3 0.5 0.039 14.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain Atracotoxin PF05353.6 KFY04777.1 - 0.1 12.4 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Delta Atracotoxin CorA PF01544.13 KFY04779.1 - 1.3e-07 31.0 3.3 2.6e-07 29.9 2.3 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein NPV_P10 PF05531.7 KFY04779.1 - 0.094 12.9 3.1 5.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1214 PF06742.6 KFY04780.1 - 2.8e-09 37.3 0.7 0.00051 20.4 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1214) GPI-anchored PF10342.4 KFY04780.1 - 0.02 15.3 1.4 0.17 12.3 0.1 2.7 2 0 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Big_3_4 PF13754.1 KFY04780.1 - 0.049 13.9 4.0 0.73 10.1 0.4 2.8 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) DUF2670 PF10875.3 KFY04780.1 - 0.088 12.8 0.0 0.25 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) He_PIG PF05345.7 KFY04780.1 - 0.18 11.8 3.3 2.7 8.0 0.2 2.9 2 0 0 2 2 2 0 Putative Ig domain Fungal_trans PF04082.13 KFY04781.1 - 6.3e-64 215.3 0.2 1e-63 214.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 KFY04781.1 - 7.7e-07 29.1 9.9 0.00014 21.9 0.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KFY04781.1 - 5.4e-06 26.3 9.6 0.00025 21.1 0.4 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KFY04781.1 - 0.0028 17.8 1.3 0.0028 17.8 0.9 2.9 3 0 0 3 3 3 2 Zinc-finger double domain Pkinase PF00069.20 KFY04785.1 - 1.1e-51 175.5 0.0 1.5e-51 175.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY04785.1 - 2.4e-27 95.6 0.1 7.3e-27 94.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KFY04785.1 - 0.1 11.5 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Dicty_CAR PF05462.6 KFY04789.1 - 2.1e-16 59.7 5.9 2.1e-16 59.7 4.1 2.0 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 KFY04789.1 - 7.8e-08 31.6 6.1 7.8e-08 31.6 4.2 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Git3 PF11710.3 KFY04789.1 - 1.7e-07 30.9 11.6 3.5e-07 29.9 8.1 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.4 KFY04789.1 - 0.00012 21.3 4.8 0.00021 20.5 3.3 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx DUF3554 PF12074.3 KFY04789.1 - 0.00016 21.2 0.3 0.46 9.8 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF3554) Put_Phosphatase PF06888.7 KFY04789.1 - 0.14 11.2 0.0 18 4.3 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase Zn_clus PF00172.13 KFY04793.1 - 4.3e-07 29.7 8.9 6.6e-07 29.1 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFY04793.1 - 0.0023 16.6 0.1 0.0038 15.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FUSC_2 PF13515.1 KFY04794.1 - 0.084 12.7 1.0 0.16 11.8 0.7 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein-like Beach PF02138.13 KFY04795.1 - 4.8e-107 357.4 0.1 1.1e-106 356.2 0.0 1.7 1 0 0 1 1 1 1 Beige/BEACH domain HLH PF00010.21 KFY04795.1 - 6.2e-16 57.8 0.2 3.4e-15 55.4 0.1 2.3 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain PH_BEACH PF14844.1 KFY04795.1 - 4.4e-10 39.3 0.0 1.1e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 KFY04795.1 - 5.5e-10 39.6 0.0 1.2e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 KFY04795.1 - 4.8e-08 32.5 0.6 0.0002 21.0 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Peptidase_S8 PF00082.17 KFY04796.1 - 5.7e-53 179.8 8.6 5.7e-53 179.8 6.0 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KFY04796.1 - 1.2e-19 70.6 0.2 1.2e-19 70.6 0.1 1.9 2 0 0 2 2 2 1 Peptidase inhibitor I9 Pkinase PF00069.20 KFY04798.1 - 1.4e-60 204.6 0.0 2e-60 204.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY04798.1 - 3.1e-29 101.8 0.0 4.5e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Abhydro_lipase PF04083.11 KFY04798.1 - 2.2e-21 74.9 0.1 4.3e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KFY04798.1 - 4.1e-15 55.9 0.2 1.6e-14 54.0 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Kinase-like PF14531.1 KFY04798.1 - 9.1e-05 21.5 0.0 0.00014 20.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Abhydrolase_5 PF12695.2 KFY04798.1 - 0.00018 21.2 0.0 0.0012 18.6 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KFY04798.1 - 0.0016 17.9 0.0 0.3 10.4 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) APH PF01636.18 KFY04798.1 - 0.014 15.1 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KFY04798.1 - 0.13 11.2 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KFY04798.1 - 0.35 9.6 0.0 0.59 8.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RRM_1 PF00076.17 KFY04799.1 - 1.9e-15 56.2 0.0 3.9e-15 55.2 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY04799.1 - 8.9e-12 44.8 0.0 1.5e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFY04799.1 - 2.2e-05 24.1 0.0 3.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KFY04799.1 - 0.00032 20.3 0.0 0.00057 19.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Methyltransf_3 PF01596.12 KFY04800.1 - 1.1e-37 129.0 0.0 1.8e-37 128.4 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 KFY04800.1 - 1.1e-12 47.8 0.0 1.5e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 KFY04800.1 - 1.6e-10 41.7 0.0 6.4e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 KFY04800.1 - 2.1e-10 40.4 0.0 2.8e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KFY04800.1 - 3.8e-09 37.1 0.0 8.3e-09 36.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KFY04800.1 - 1.4e-07 31.5 0.0 2.1e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY04800.1 - 5.5e-06 26.6 0.0 1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 KFY04800.1 - 0.00019 21.0 0.0 0.00028 20.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.13 KFY04800.1 - 0.00071 18.7 0.0 0.00088 18.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KFY04800.1 - 0.0017 17.7 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 KFY04800.1 - 0.0022 18.4 0.1 0.0085 16.5 0.0 2.0 3 0 0 3 3 2 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KFY04800.1 - 0.0066 15.8 0.0 0.0091 15.3 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.7 KFY04800.1 - 0.014 15.8 0.1 0.028 14.8 0.0 1.6 2 0 0 2 2 1 0 Methyltransferase domain Fibrillarin PF01269.12 KFY04800.1 - 0.064 12.1 0.0 0.08 11.8 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin PNTB PF02233.11 KFY04806.1 - 2.4e-166 554.0 23.2 2.4e-166 554.0 16.0 1.9 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit Arylsulfotran_2 PF14269.1 KFY04806.1 - 2.9e-74 249.9 2.5 4.4e-74 249.3 1.8 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) AlaDh_PNT_C PF01262.16 KFY04806.1 - 1.1e-53 181.2 1.8 2e-53 180.3 1.2 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KFY04806.1 - 3.2e-38 130.7 0.0 8.5e-38 129.4 0.0 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 KFY04806.1 - 1e-31 108.8 3.2 1e-31 108.8 2.2 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF3814) Arylsulfotrans PF05935.6 KFY04806.1 - 3.5e-16 58.7 0.9 1.6e-15 56.5 0.6 1.8 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) 2-Hacid_dh_C PF02826.14 KFY04806.1 - 0.019 14.1 0.4 1.5 7.9 0.0 2.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.17 KFY04806.1 - 0.022 14.4 0.3 0.08 12.6 0.2 2.0 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Pyr_redox_2 PF07992.9 KFY04806.1 - 0.075 12.9 0.7 0.22 11.3 0.5 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFY04806.1 - 0.099 11.4 0.8 0.2 10.4 0.6 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Tol_Tol_Ttg2 PF05494.7 KFY04806.1 - 0.16 11.5 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 Toluene tolerance, Ttg2 Methyltransf_31 PF13847.1 KFY04806.1 - 0.18 11.4 0.1 1 8.9 0.0 2.2 3 0 0 3 3 3 0 Methyltransferase domain MFS_1 PF07690.11 KFY04807.1 - 6.5e-42 143.5 30.3 6.5e-42 143.5 21.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY04807.1 - 7.3e-16 57.7 21.1 5.3e-13 48.3 7.9 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFY04808.1 - 3.1e-27 95.2 20.8 4e-27 94.8 14.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KFY04808.1 - 0.21 11.4 7.7 0.57 10.0 1.4 2.7 2 0 0 2 2 2 0 MFS_1 like family DUF1996 PF09362.5 KFY04809.1 - 6.4e-47 160.1 1.4 2.7e-26 92.6 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1996) FMO-like PF00743.14 KFY04811.1 - 3.2e-16 58.6 0.0 6.2e-14 51.0 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KFY04811.1 - 5.9e-12 46.0 0.0 1.3e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFY04811.1 - 1.9e-07 31.0 0.0 6.4e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KFY04811.1 - 5.2e-05 23.0 0.0 0.00015 21.5 0.0 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KFY04811.1 - 9.3e-05 22.3 0.0 0.00022 21.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFY04811.1 - 0.0015 17.0 0.1 0.0031 16.0 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 KFY04811.1 - 0.0043 16.0 0.0 0.47 9.3 0.0 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFY04811.1 - 0.0098 16.2 0.0 2.3 8.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KFY04811.1 - 0.015 14.3 0.0 0.054 12.5 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Thi4 PF01946.12 KFY04811.1 - 0.027 13.5 0.1 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 KFY04811.1 - 0.045 12.5 0.0 0.072 11.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain DUF3782 PF12644.2 KFY04811.1 - 0.089 12.5 0.0 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) K_oxygenase PF13434.1 KFY04811.1 - 0.13 11.1 0.0 0.32 9.8 0.0 1.6 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 KFY04811.1 - 0.17 12.1 0.0 4.9 7.4 0.0 2.7 3 0 0 3 3 3 0 Putative NAD(P)-binding Amidohydro_4 PF13147.1 KFY04812.1 - 1.7e-26 93.8 0.4 5.1e-15 56.2 0.2 2.3 1 1 1 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 KFY04812.1 - 2.2e-12 47.2 0.4 1.4e-09 38.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 KFY04812.1 - 5.5e-12 45.6 2.6 1e-09 38.1 0.1 2.3 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KFY04812.1 - 2.8e-08 33.4 0.1 1.5e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase Aldose_epim PF01263.15 KFY04814.1 - 1.4e-47 162.2 0.4 1.7e-47 161.9 0.3 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Ank_2 PF12796.2 KFY04816.1 - 7.4e-95 311.4 11.7 8.8e-19 67.6 0.1 8.2 3 2 6 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.25 KFY04816.1 - 8e-80 258.9 8.6 3.2e-07 29.8 0.0 14.9 14 1 0 14 14 14 14 Ankyrin repeat Ank_3 PF13606.1 KFY04816.1 - 9.5e-67 214.2 0.2 0.00017 21.5 0.0 15.1 15 0 0 15 15 15 12 Ankyrin repeat Ank_4 PF13637.1 KFY04816.1 - 9.5e-58 191.6 1.0 3.5e-09 36.9 0.0 11.3 6 3 7 13 13 13 12 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY04816.1 - 2.8e-48 160.8 6.3 3.6e-08 33.3 0.0 11.4 5 3 7 12 12 12 11 Ankyrin repeats (many copies) zf-LYAR PF08790.6 KFY04816.1 - 0.14 11.9 1.5 6.4 6.5 0.1 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Shigella_OspC PF06128.6 KFY04816.1 - 0.3 10.5 2.0 43 3.4 0.0 4.0 4 0 0 4 4 4 0 Shigella flexneri OspC protein DUF4136 PF13590.1 KFY04820.1 - 0.047 13.7 0.1 0.063 13.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4136) PH PF00169.24 KFY04823.1 - 4.8e-05 23.5 0.0 0.00092 19.3 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 KFY04823.1 - 0.003 17.7 0.0 0.0076 16.3 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Pyr_redox_3 PF13738.1 KFY04828.1 - 1.2e-25 90.7 0.0 2.5e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFY04828.1 - 4.9e-22 77.8 1.9 5.8e-18 64.3 0.2 2.9 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KFY04828.1 - 1e-10 41.1 0.2 2.7e-06 26.5 0.0 4.1 3 1 1 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KFY04828.1 - 1.9e-10 40.6 0.0 5e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFY04828.1 - 1.7e-05 24.8 0.0 0.0028 17.5 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KFY04828.1 - 0.00079 18.4 0.0 0.012 14.5 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KFY04828.1 - 0.0008 19.2 3.4 0.033 13.9 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 KFY04828.1 - 0.029 13.4 0.3 0.13 11.3 0.0 2.1 3 0 0 3 3 3 0 Thi4 family GIDA PF01134.17 KFY04828.1 - 0.083 11.7 0.3 5.5 5.7 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Malic_M PF03949.10 KFY04828.1 - 0.12 11.9 0.0 0.6 9.6 0.0 2.0 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Shikimate_DH PF01488.15 KFY04828.1 - 0.16 12.1 0.2 27 4.8 0.0 3.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Fe-ADH PF00465.14 KFY04829.1 - 7.3e-68 228.8 0.0 9.1e-68 228.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KFY04829.1 - 9.2e-05 21.8 0.0 0.0092 15.3 0.0 2.1 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Zn_clus PF00172.13 KFY04830.1 - 6.8e-09 35.4 4.8 1.4e-08 34.5 3.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFY04830.1 - 2.2e-05 23.2 3.1 0.00012 20.8 2.2 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 KFY04831.1 - 1.5e-78 264.4 30.2 1.7e-78 264.2 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY04831.1 - 9.3e-18 64.0 33.2 9.3e-18 64.0 23.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.23 KFY04832.1 - 1.5e-85 287.1 0.1 2.4e-84 283.1 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme Abhydrolase_3 PF07859.8 KFY04832.1 - 1.9e-52 177.8 0.0 3.2e-52 177.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold AMP-binding_C PF13193.1 KFY04832.1 - 1.3e-10 42.0 0.0 1e-09 39.2 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain COesterase PF00135.23 KFY04832.1 - 8.2e-06 24.8 0.0 2.3e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Thiolase_N PF00108.18 KFY04833.1 - 5.6e-95 317.2 0.3 7.9e-95 316.7 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFY04833.1 - 3.3e-38 129.8 0.4 3.3e-38 129.8 0.3 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KFY04833.1 - 1.8e-05 24.3 2.2 3.3e-05 23.4 0.7 2.0 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Aldo_ket_red PF00248.16 KFY04836.1 - 7.1e-51 172.6 0.0 8.6e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Esterase_phd PF10503.4 KFY04837.1 - 1.8e-21 76.4 2.3 2.3e-21 76.0 1.6 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 KFY04837.1 - 1.3e-13 50.6 0.7 1.9e-13 50.1 0.5 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KFY04837.1 - 1.2e-08 34.8 0.5 1.8e-08 34.2 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFY04837.1 - 3.3e-05 23.8 0.2 0.00011 22.1 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family CBM_1 PF00734.13 KFY04837.1 - 0.00026 20.6 7.5 0.00026 20.6 5.2 3.0 3 0 0 3 3 3 1 Fungal cellulose binding domain Abhydrolase_1 PF00561.15 KFY04837.1 - 0.0042 16.6 0.1 0.0051 16.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 KFY04837.1 - 0.021 14.2 1.3 0.03 13.7 0.3 1.7 2 0 0 2 2 2 0 Putative esterase FSH1 PF03959.8 KFY04837.1 - 0.033 13.6 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) COesterase PF00135.23 KFY04837.1 - 0.072 11.7 0.7 0.11 11.2 0.5 1.3 1 0 0 1 1 1 0 Carboxylesterase family Abhydrolase_2 PF02230.11 KFY04837.1 - 0.17 11.2 0.4 0.39 10.1 0.3 1.7 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Ribonuclease PF00545.15 KFY04838.1 - 3.9e-19 68.5 0.0 5.5e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 ribonuclease Flavi_NS1 PF00948.16 KFY04838.1 - 0.012 14.0 0.1 0.012 14.0 0.0 1.1 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 DUF3632 PF12311.3 KFY04839.1 - 2.7e-37 128.3 0.5 3.3e-37 128.0 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Epimerase PF01370.16 KFY04840.1 - 3.2e-12 46.3 0.0 5.1e-12 45.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KFY04840.1 - 9e-11 42.1 0.6 1.8e-10 41.1 0.4 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KFY04840.1 - 1.5e-07 30.9 0.6 2.2e-07 30.3 0.1 1.5 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 KFY04840.1 - 3.6e-07 30.2 0.1 6.3e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 KFY04840.1 - 2.8e-05 23.1 0.6 0.00018 20.5 0.4 2.2 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 KFY04840.1 - 4.8e-05 22.3 0.0 0.00011 21.2 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KFY04840.1 - 0.0016 17.1 0.0 0.0021 16.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KFY04840.1 - 0.0032 16.3 0.1 0.08 11.8 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.5 KFY04840.1 - 0.0065 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 KFY04840.1 - 0.015 15.6 0.0 0.038 14.4 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 KFY04840.1 - 0.034 13.5 0.0 0.068 12.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 KFY04840.1 - 0.065 13.0 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_3 PF03447.11 KFY04840.1 - 0.07 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain NUDIX_2 PF13869.1 KFY04841.1 - 3.2e-82 274.4 0.0 3.8e-82 274.1 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase UPF0047 PF01894.12 KFY04842.1 - 2.5e-40 136.9 0.0 6.8e-40 135.5 0.0 1.8 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Fungal_trans PF04082.13 KFY04842.1 - 3.4e-13 49.0 0.0 7.2e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY04842.1 - 4.6e-08 32.8 10.2 7.7e-08 32.1 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoaE PF01121.15 KFY04843.1 - 4.7e-43 146.6 0.0 7.5e-43 146.0 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 KFY04843.1 - 0.035 14.9 0.1 0.13 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Peptidase_M16_C PF05193.16 KFY04844.1 - 0.0007 19.3 0.0 0.0015 18.2 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain Glyco_hydro_18 PF00704.23 KFY04848.1 - 8.5e-44 150.3 0.3 1.5e-43 149.5 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 p450 PF00067.17 KFY04848.1 - 9.7e-40 136.4 0.0 1.3e-38 132.6 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Hce2 PF14856.1 KFY04848.1 - 1.6e-22 79.2 0.8 5.7e-22 77.4 0.6 2.0 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor HATPase_c PF02518.21 KFY04848.1 - 1.7e-17 63.1 0.0 3.6e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KFY04848.1 - 2.5e-13 49.8 0.0 1.2e-12 47.6 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain LysM PF01476.15 KFY04848.1 - 3.4e-06 26.8 0.2 0.0034 17.2 0.0 3.0 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 KFY04848.1 - 0.00032 20.6 2.8 0.0017 18.3 1.9 2.3 1 0 0 1 1 1 1 Chitin recognition protein LysM PF01476.15 KFY04850.1 - 3.5e-16 58.8 3.9 0.001 18.9 0.0 4.3 4 0 0 4 4 4 4 LysM domain HTH_Tnp_1 PF01527.15 KFY04850.1 - 0.012 15.5 0.0 25 4.9 0.0 3.2 3 0 0 3 3 3 0 Transposase DUF1153 PF06627.6 KFY04850.1 - 0.026 14.3 0.1 23 4.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1153) UPF0203 PF05254.7 KFY04850.1 - 0.52 10.1 13.6 9.9 6.1 0.7 4.1 3 3 0 3 3 3 0 Uncharacterised protein family (UPF0203) DUF4203 PF13886.1 KFY04852.1 - 1e-34 119.8 24.4 1e-34 119.8 16.9 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) Mucin PF01456.12 KFY04852.1 - 0.014 15.2 9.4 0.024 14.3 6.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2217 PF10265.4 KFY04852.1 - 0.27 9.9 2.1 1.7 7.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) Shisa PF13908.1 KFY04852.1 - 0.71 10.0 5.8 44 4.1 4.5 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator NfeD PF01957.13 KFY04852.1 - 1.7 8.7 0.0 1.7 8.7 0.0 3.2 2 1 1 4 4 4 0 NfeD-like C-terminal, partner-binding SSB PF00436.20 KFY04853.1 - 5.1e-18 64.8 0.0 6e-18 64.6 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family GSH_synth_ATP PF03917.12 KFY04856.1 - 3.3e-112 374.7 0.0 4.1e-112 374.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KFY04856.1 - 3e-34 117.2 0.0 5.3e-34 116.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.18 KFY04857.1 - 6.6e-42 143.3 0.0 1.1e-41 142.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KFY04857.1 - 1.4e-14 53.7 0.0 6.6e-14 51.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KFY04857.1 - 0.01 15.6 0.0 0.096 12.5 0.0 2.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_14 PF13173.1 KFY04857.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain 2-Hacid_dh_C PF02826.14 KFY04858.1 - 2.4e-51 173.3 0.0 3.8e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFY04858.1 - 4e-36 123.4 0.1 5.2e-36 123.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFY04858.1 - 8.4e-05 22.4 0.2 0.00074 19.4 0.1 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 KFY04858.1 - 0.0027 17.1 1.1 0.015 14.7 0.1 2.7 2 1 0 2 2 2 1 ACT domain AdoHcyase_NAD PF00670.16 KFY04858.1 - 0.0029 17.4 0.0 0.0075 16.1 0.0 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAP PF00956.13 KFY04859.1 - 3.9e-89 297.9 9.9 3.9e-89 297.9 6.9 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) TFIIA PF03153.8 KFY04859.1 - 0.21 11.4 21.5 0.56 10.0 8.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit P5-ATPase PF12409.3 KFY04860.1 - 2.1e-36 124.3 0.0 2.1e-36 124.3 0.0 1.9 2 0 0 2 2 2 1 P5-type ATPase cation transporter HAD PF12710.2 KFY04860.1 - 2.4e-29 102.9 0.0 4.9e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KFY04860.1 - 6.1e-27 94.1 0.0 1.1e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 KFY04860.1 - 2.3e-13 51.0 0.0 6.5e-09 36.5 0.0 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 KFY04860.1 - 6.6e-05 22.5 6.8 6.6e-05 22.5 4.7 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 KFY04860.1 - 0.013 15.4 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KFY04860.1 - 0.22 11.0 0.1 1.5 8.3 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase tRNA-synt_2b PF00587.20 KFY04861.1 - 1.9e-36 125.2 0.1 3.1e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KFY04861.1 - 1.2e-19 70.3 7.4 1.2e-19 70.3 5.2 2.3 3 0 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 KFY04861.1 - 0.036 13.7 6.3 0.028 14.0 3.0 1.8 2 0 0 2 2 2 0 Mnd1 family Ras PF00071.17 KFY04862.1 - 8e-46 155.3 1.0 9.1e-46 155.1 0.7 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFY04862.1 - 6e-15 55.7 0.3 8.7e-15 55.2 0.2 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFY04862.1 - 2e-08 33.7 0.0 2.2e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFY04862.1 - 8.5e-08 31.8 0.2 2.3e-06 27.1 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KFY04862.1 - 7e-06 25.9 0.1 9.4e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KFY04862.1 - 0.0015 17.7 0.1 0.0028 16.8 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 KFY04862.1 - 0.011 15.6 0.0 0.21 11.5 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 KFY04862.1 - 0.022 14.6 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 KFY04862.1 - 0.028 13.6 0.0 0.34 10.1 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Arch_ATPase PF01637.13 KFY04862.1 - 0.18 11.5 0.7 0.55 9.8 0.5 1.9 1 1 0 1 1 1 0 Archaeal ATPase WAPL PF07814.8 KFY04863.1 - 1.8e-20 73.0 0.2 1.2e-15 57.1 0.0 2.1 2 0 0 2 2 2 2 Wings apart-like protein regulation of heterochromatin UPRTase PF14681.1 KFY04864.1 - 7.1e-78 260.5 0.0 8.8e-78 260.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KFY04864.1 - 0.0013 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 KFY04864.1 - 0.021 14.5 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Elf1 PF05129.8 KFY04865.1 - 2e-27 94.6 2.2 2.8e-27 94.2 1.6 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like GTP_CH_N PF12471.3 KFY04866.1 - 2.5e-89 298.1 0.0 3.6e-89 297.5 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 KFY04866.1 - 3.5e-16 58.9 0.0 5.9e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Ribosomal_S3Ae PF01015.13 KFY04868.1 - 7.8e-81 270.0 6.4 1.3e-80 269.3 4.5 1.3 1 0 0 1 1 1 1 Ribosomal S3Ae family Ras PF00071.17 KFY04868.1 - 4e-42 143.3 0.0 8.5e-42 142.2 0.0 1.5 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KFY04868.1 - 7.9e-07 29.5 0.0 2e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KFY04868.1 - 6.4e-06 25.5 0.0 1.3e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFY04868.1 - 0.0085 15.5 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Abhydrolase_6 PF12697.2 KFY04869.1 - 1.5e-30 106.7 0.0 2.3e-30 106.2 0.0 1.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY04869.1 - 8e-23 81.1 0.0 3.7e-22 78.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFY04869.1 - 3.4e-14 52.8 0.0 5.5e-14 52.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KFY04869.1 - 2.6e-05 23.9 0.0 3.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 KFY04869.1 - 3.6e-05 24.0 0.0 4.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.9 KFY04869.1 - 0.00016 20.3 0.0 0.00019 19.9 0.0 1.4 1 1 0 1 1 1 1 Ndr family Esterase PF00756.15 KFY04869.1 - 0.0011 18.5 0.0 0.0013 18.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Chlorophyllase PF07224.6 KFY04869.1 - 0.0027 16.5 0.0 0.0038 16.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Ser_hydrolase PF06821.8 KFY04869.1 - 0.029 13.9 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Lipase_3 PF01764.20 KFY04869.1 - 0.031 13.8 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.3 KFY04869.1 - 0.053 13.3 0.2 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DUF2974 PF11187.3 KFY04869.1 - 0.072 12.4 0.0 0.099 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.8 KFY04869.1 - 0.084 12.4 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold tRNA-synt_1b PF00579.20 KFY04870.1 - 1.9e-67 227.4 0.0 2.6e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Ribosomal_S10 PF00338.17 KFY04870.1 - 2.4e-23 81.7 0.0 9e-23 79.9 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e Fcf2 PF08698.6 KFY04871.1 - 2.2e-31 107.7 0.3 4.8e-31 106.7 0.1 1.6 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing TGF_beta_GS PF08515.7 KFY04871.1 - 0.08 12.2 5.7 0.23 10.8 4.0 1.7 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif CBFD_NFYB_HMF PF00808.18 KFY04872.1 - 1.4e-19 69.8 0.6 2.4e-19 69.1 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KFY04872.1 - 1.6e-11 44.1 1.6 3.5e-11 43.0 0.1 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 PAT1 PF09770.4 KFY04872.1 - 0.022 13.0 12.6 0.031 12.5 8.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CENP-X PF09415.5 KFY04872.1 - 0.025 14.3 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Sec15 PF04091.7 KFY04873.1 - 2.6e-123 411.2 0.5 2.6e-123 411.2 0.3 2.0 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like COG2 PF06148.6 KFY04873.1 - 0.00078 19.3 6.0 0.00078 19.3 4.2 3.3 3 1 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.9 KFY04873.1 - 0.0013 18.3 6.3 0.0013 18.3 4.3 2.6 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain COG5 PF10392.4 KFY04873.1 - 0.003 17.4 7.1 0.0083 16.0 3.7 2.6 2 0 0 2 2 2 1 Golgi transport complex subunit 5 COG7 PF10191.4 KFY04873.1 - 0.023 12.6 10.4 0.27 9.1 3.6 2.8 3 0 0 3 3 3 0 Golgi complex component 7 (COG7) DUF2450 PF10475.4 KFY04873.1 - 0.037 12.9 12.2 0.0085 15.0 5.7 1.8 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) Vps51 PF08700.6 KFY04873.1 - 0.11 12.4 4.4 0.25 11.2 1.2 2.9 2 0 0 2 2 2 0 Vps51/Vps67 Sec5 PF15469.1 KFY04873.1 - 0.11 12.2 7.4 0.094 12.4 2.1 2.7 2 1 0 2 2 2 0 Exocyst complex component Sec5 RRM_2 PF04059.7 KFY04874.1 - 4e-40 135.7 0.3 7.1e-40 134.9 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 KFY04874.1 - 0.0001 21.8 0.0 0.12 12.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY04874.1 - 0.013 15.5 0.0 7.3 6.6 0.0 2.8 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFY04874.1 - 0.048 13.5 0.1 2.2 8.2 0.0 3.0 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Xpo1 PF08389.7 KFY04875.1 - 0.00065 19.6 0.4 0.023 14.6 0.0 3.0 2 0 0 2 2 2 1 Exportin 1-like protein FUN14 PF04930.10 KFY04876.1 - 4.3e-08 33.3 1.3 4.8e-07 29.9 1.1 2.2 2 1 0 2 2 2 1 FUN14 family Sad1_UNC PF07738.8 KFY04877.1 - 1.2e-36 125.4 0.0 1.9e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal ABC_membrane PF00664.18 KFY04882.1 - 1.1e-75 254.5 27.6 4.3e-42 144.4 4.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KFY04882.1 - 2.3e-62 209.3 0.0 3.8e-31 108.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KFY04882.1 - 4.3e-15 55.5 2.7 0.00046 19.4 0.0 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KFY04882.1 - 3.4e-10 40.3 0.2 0.048 13.6 0.0 4.3 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 KFY04882.1 - 3e-09 37.1 1.4 0.00098 19.1 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KFY04882.1 - 4e-09 35.8 0.4 0.0012 18.3 0.0 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.12 KFY04882.1 - 4.2e-08 33.2 1.0 0.0001 22.1 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_17 PF13207.1 KFY04882.1 - 3.8e-07 30.9 0.0 0.038 14.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KFY04882.1 - 3.8e-07 30.2 1.3 0.28 11.3 0.1 4.4 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KFY04882.1 - 1.2e-06 28.2 1.5 0.31 10.5 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_19 PF13245.1 KFY04882.1 - 5e-06 26.1 0.2 0.024 14.3 0.0 3.6 2 0 0 2 2 2 2 Part of AAA domain DUF258 PF03193.11 KFY04882.1 - 1.6e-05 24.1 0.0 0.026 13.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ABC_ATPase PF09818.4 KFY04882.1 - 1.8e-05 23.5 0.1 0.024 13.2 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_25 PF13481.1 KFY04882.1 - 3.8e-05 23.1 0.7 0.18 11.1 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_10 PF12846.2 KFY04882.1 - 9.9e-05 21.9 0.5 0.11 11.9 0.0 2.6 2 0 0 2 2 2 2 AAA-like domain AAA_23 PF13476.1 KFY04882.1 - 0.00011 22.6 0.9 0.14 12.4 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KFY04882.1 - 0.0004 20.2 0.5 1.3 8.9 0.1 2.9 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KFY04882.1 - 0.00051 19.9 0.2 1.1 9.1 0.0 3.4 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KFY04882.1 - 0.00059 20.1 0.1 0.99 9.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KFY04882.1 - 0.0014 18.8 1.2 8.3 6.6 0.2 3.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KFY04882.1 - 0.0038 16.3 0.1 0.39 9.7 0.0 2.6 3 0 0 3 3 2 1 Zeta toxin FtsK_SpoIIIE PF01580.13 KFY04882.1 - 0.0042 16.5 0.0 0.055 12.9 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family PRK PF00485.13 KFY04882.1 - 0.0064 16.0 0.3 24 4.3 0.0 3.3 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.18 KFY04882.1 - 0.012 15.6 0.1 3 7.8 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase APS_kinase PF01583.15 KFY04882.1 - 0.013 15.1 0.1 3.7 7.1 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_5 PF07728.9 KFY04882.1 - 0.019 14.7 0.0 4.4 7.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 KFY04882.1 - 0.033 13.6 0.2 9 5.6 0.0 2.8 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain DUF3987 PF13148.1 KFY04882.1 - 0.045 12.3 0.3 5.8 5.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) MobB PF03205.9 KFY04882.1 - 0.065 12.9 0.7 13 5.5 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.15 KFY04882.1 - 0.17 10.5 0.0 14 4.2 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Acetyltransf_8 PF13523.1 KFY04883.1 - 1.8e-35 122.0 0.1 2.7e-35 121.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ECH PF00378.15 KFY04884.1 - 1e-48 165.6 0.0 1.3e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family MFS_1 PF07690.11 KFY04885.1 - 2e-23 82.6 56.3 1.8e-15 56.5 22.5 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 KFY04885.1 - 3.9e-09 35.2 29.2 5.6e-09 34.7 19.9 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AMP-binding PF00501.23 KFY04886.1 - 3.7e-82 275.9 0.0 3.9e-76 256.1 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 KFY04886.1 - 4.3e-67 226.1 0.0 7.2e-38 130.1 0.0 2.5 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.20 KFY04886.1 - 3.4e-24 84.8 0.0 1.6e-11 44.3 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KFY04886.1 - 1.4e-06 29.1 0.0 0.1 13.5 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain AATase PF07247.7 KFY04886.1 - 0.069 11.6 0.4 2.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Alcohol acetyltransferase DUF1749 PF08538.5 KFY04887.1 - 7.9e-98 327.0 0.0 8.9e-98 326.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 KFY04887.1 - 7.6e-07 29.2 0.0 1.5e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KFY04887.1 - 1.4e-06 28.1 0.0 2.5e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KFY04887.1 - 0.00058 19.5 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 KFY04887.1 - 0.0087 15.6 0.3 0.051 13.1 0.1 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF2305 PF10230.4 KFY04887.1 - 0.041 13.2 0.0 0.58 9.5 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2305) Hepar_II_III PF07940.8 KFY04888.1 - 1.4e-14 54.0 0.1 3.4e-14 52.8 0.1 1.6 1 0 0 1 1 1 1 Heparinase II/III-like protein Fungal_trans PF04082.13 KFY04889.1 - 1.4e-17 63.4 0.1 4.5e-17 61.7 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY04889.1 - 1.8e-06 27.7 10.9 2.9e-06 27.0 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2264 PF10022.4 KFY04890.1 - 2.6e-127 424.4 0.1 3.2e-127 424.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Glyco_hydro_88 PF07470.8 KFY04891.1 - 1.9e-10 40.2 0.5 6.5e-10 38.5 0.1 1.9 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 Sugar_tr PF00083.19 KFY04892.1 - 2.8e-76 256.9 22.8 3.2e-76 256.7 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY04892.1 - 1.7e-37 128.9 51.3 8.3e-31 106.9 17.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KFY04892.1 - 4.2e-05 22.1 25.4 0.0022 16.4 7.1 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 KFY04892.1 - 0.00027 19.2 0.5 0.00056 18.2 0.4 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2463 PF09591.5 KFY04892.1 - 0.01 15.4 0.7 2.6 7.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) MFS_1_like PF12832.2 KFY04892.1 - 0.016 15.0 1.0 0.63 9.8 0.0 3.7 4 0 0 4 4 4 0 MFS_1 like family COesterase PF00135.23 KFY04893.1 - 2.6e-97 326.7 0.0 3.1e-97 326.5 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KFY04893.1 - 1.3e-07 31.4 0.0 4.8e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KFY04893.1 - 0.0051 16.0 0.2 0.0075 15.5 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Sulfakinin PF08257.6 KFY04893.1 - 0.19 11.6 0.9 0.54 10.2 0.6 1.8 1 0 0 1 1 1 0 Sulfakinin family Glyco_hydro_28 PF00295.12 KFY04894.1 - 4.2e-34 117.9 9.4 6.1e-34 117.4 6.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Zn_clus PF00172.13 KFY04895.1 - 4e-09 36.2 10.1 7e-09 35.4 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KFY04895.1 - 1.8e-06 26.8 0.1 2.6e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peroxidase_2 PF01328.12 KFY04896.1 - 4e-40 137.4 0.1 5e-40 137.1 0.1 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 DUF4633 PF15464.1 KFY04899.1 - 0.04 13.7 1.0 0.93 9.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) Mto2_bdg PF12808.2 KFY04899.1 - 0.073 13.1 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region FA_hydroxylase PF04116.8 KFY04902.1 - 2.5e-16 60.1 18.4 2.5e-16 60.1 12.7 2.4 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily NCA2 PF08637.5 KFY04903.1 - 8.8e-87 290.6 0.0 1.3e-86 290.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Pyridoxal_deC PF00282.14 KFY04903.1 - 5.7e-80 268.5 0.0 7.6e-80 268.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 KFY04903.1 - 4.8e-08 32.4 0.0 8e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KFY04903.1 - 2.1e-07 29.9 0.0 4.5e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V HEM4 PF02602.10 KFY04903.1 - 0.026 13.7 0.0 0.053 12.7 0.0 1.4 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD ADH_N PF08240.7 KFY04909.1 - 2.3e-29 101.3 0.4 3.8e-29 100.6 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KFY04909.1 - 3.5e-15 55.7 0.0 5.6e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KFY04909.1 - 0.0064 16.1 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Pyr_redox_3 PF13738.1 KFY04909.1 - 0.17 11.9 0.0 0.25 11.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.23 KFY04910.1 - 2.2e-87 293.1 0.0 2.8e-87 292.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KFY04910.1 - 5.5e-13 49.6 0.0 5.4e-12 46.4 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.13 KFY04911.1 - 8.2e-18 64.2 2.3 1.2e-17 63.6 1.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ECH PF00378.15 KFY04912.1 - 2.7e-33 115.1 0.0 1.8e-23 82.9 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family NMO PF03060.10 KFY04913.1 - 3e-68 230.4 1.0 5.1e-68 229.6 0.7 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KFY04913.1 - 4.9e-06 25.6 0.0 0.0013 17.6 0.0 2.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KFY04913.1 - 0.0066 15.3 2.0 0.014 14.3 1.4 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase MFS_1 PF07690.11 KFY04914.1 - 6.3e-31 107.3 33.6 6.3e-31 107.3 23.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Thiolase_C PF02803.13 KFY04915.1 - 0.067 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Thiolase, C-terminal domain AMP-binding PF00501.23 KFY04916.1 - 1.3e-75 254.4 0.0 2.1e-75 253.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Fungal_trans PF04082.13 KFY04916.1 - 4.3e-23 81.5 0.0 8.7e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pyr_redox_3 PF13738.1 KFY04916.1 - 8.9e-23 81.4 0.0 1.8e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFY04916.1 - 3.3e-12 45.3 0.1 8.6e-11 40.7 0.0 2.3 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KFY04916.1 - 2.2e-11 43.6 0.0 6.7e-11 42.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AMP-binding_C PF13193.1 KFY04916.1 - 3e-11 44.1 0.1 7.7e-11 42.7 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Zn_clus PF00172.13 KFY04916.1 - 3.5e-09 36.4 11.7 7e-09 35.4 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.9 KFY04916.1 - 1.5e-06 28.2 0.0 1.1e-05 25.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lactamase_B PF00753.22 KFY04916.1 - 6.2e-06 25.9 0.5 1.3e-05 24.9 0.4 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily K_oxygenase PF13434.1 KFY04916.1 - 0.0002 20.4 0.0 0.041 12.7 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KFY04916.1 - 0.00027 20.7 0.0 0.0015 18.3 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 KFY04916.1 - 0.00057 18.8 0.0 0.11 11.4 0.0 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lactamase_B_2 PF12706.2 KFY04916.1 - 0.0014 18.1 0.1 0.0038 16.8 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Thi4 PF01946.12 KFY04916.1 - 0.017 14.1 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.15 KFY04916.1 - 0.21 11.7 0.2 12 6.0 0.1 3.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KFY04916.1 - 0.21 11.9 0.0 1.8 9.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aldedh PF00171.17 KFY04917.1 - 1.2e-158 528.3 0.2 1.3e-158 528.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Recep_L_domain PF01030.19 KFY04918.1 - 0.014 15.3 0.0 3.2 7.7 0.0 3.7 2 1 2 4 4 4 0 Receptor L domain Pec_lyase_C PF00544.14 KFY04919.1 - 6.3e-31 107.4 2.6 8.6e-31 106.9 1.8 1.1 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 KFY04919.1 - 6.1e-05 22.8 14.4 0.00024 20.9 8.8 2.2 1 1 1 2 2 2 2 Right handed beta helix region YtxH PF12732.2 KFY04922.1 - 0.16 12.3 0.7 0.42 11.0 0.5 1.6 1 0 0 1 1 1 0 YtxH-like protein tRNA-synt_2 PF00152.15 KFY04923.1 - 4.8e-70 235.9 0.0 7.1e-70 235.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KFY04923.1 - 0.0022 17.8 0.1 0.0051 16.6 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain NinG PF05766.7 KFY04923.1 - 0.045 13.4 1.9 0.096 12.4 1.3 1.5 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein DUF883 PF05957.8 KFY04923.1 - 0.38 11.1 3.2 1.2 9.6 2.2 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) YqzL PF14006.1 KFY04924.1 - 0.2 11.8 0.2 0.2 11.8 0.1 2.8 2 1 0 2 2 2 0 YqzL-like protein zf-BED PF02892.10 KFY04925.1 - 0.0076 15.9 1.1 0.013 15.2 0.8 1.3 1 0 0 1 1 1 1 BED zinc finger DUF2201_N PF13203.1 KFY04927.1 - 0.31 10.1 3.2 0.35 9.9 2.2 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain Tom37_C PF11801.3 KFY04927.1 - 0.41 10.4 1.5 0.48 10.2 1.0 1.0 1 0 0 1 1 1 0 Tom37 C-terminal domain Fer4_18 PF13746.1 KFY04927.1 - 0.55 10.7 2.1 0.8 10.1 1.4 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain YqfQ PF14181.1 KFY04927.1 - 0.82 9.6 4.3 0.99 9.4 3.0 1.1 1 0 0 1 1 1 0 YqfQ-like protein HSP90 PF00183.13 KFY04927.1 - 1.3 7.2 7.2 1.4 7.2 5.0 1.0 1 0 0 1 1 1 0 Hsp90 protein CDC45 PF02724.9 KFY04927.1 - 4.2 5.2 6.8 4.6 5.1 4.7 1.0 1 0 0 1 1 1 0 CDC45-like protein CAF-1_p150 PF11600.3 KFY04927.1 - 4.4 6.6 20.8 5.4 6.3 14.4 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal PGBA_C PF15437.1 KFY04927.1 - 6.8 6.8 22.5 21 5.3 15.6 1.8 1 1 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal DNA_ligase_A_M PF01068.16 KFY04928.1 - 4.1e-57 192.8 0.2 2.2e-45 154.5 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KFY04928.1 - 9.6e-52 175.3 0.0 1.9e-51 174.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KFY04928.1 - 4.7e-28 97.4 0.0 3.2e-27 94.7 0.0 2.5 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region tRNA-synt_2 PF00152.15 KFY04929.1 - 4.6e-72 242.6 0.0 7.5e-72 241.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KFY04929.1 - 1.1e-08 34.8 0.0 2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Lipoprotein_16 PF03923.8 KFY04929.1 - 0.0087 15.4 0.1 0.083 12.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized lipoprotein tRNA_anti_2 PF13742.1 KFY04929.1 - 0.061 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain GMC_oxred_N PF00732.14 KFY04931.1 - 8.3e-63 212.2 0.0 1e-62 211.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KFY04931.1 - 2.5e-37 128.3 0.0 4.3e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KFY04931.1 - 1.2e-05 24.3 0.0 0.00096 18.1 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KFY04931.1 - 0.00031 19.7 0.0 0.0018 17.2 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KFY04931.1 - 0.00041 19.3 0.0 0.00094 18.1 0.0 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KFY04931.1 - 0.0011 18.8 3.4 0.0014 18.6 0.0 2.8 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KFY04931.1 - 0.0061 16.4 0.1 0.026 14.4 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFY04931.1 - 0.011 14.2 0.1 0.29 9.5 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 KFY04931.1 - 0.014 14.4 0.0 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 KFY04931.1 - 0.065 13.2 0.1 1.3 9.0 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3328 PF11807.3 KFY04932.1 - 5.1e-53 179.9 0.0 6.5e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) adh_short PF00106.20 KFY04933.1 - 2.7e-09 37.1 0.0 4e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFY04933.1 - 0.0035 17.0 0.0 0.0055 16.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KFY04933.1 - 0.064 13.3 0.0 0.099 12.7 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 KFY04933.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Hist_deacetyl PF00850.14 KFY04934.1 - 4.8e-91 305.3 0.0 7.5e-91 304.6 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 KFY04934.1 - 1.6e-37 128.6 0.3 2.4e-37 128.0 0.2 1.3 1 0 0 1 1 1 1 Arb2 domain Glyco_hydro_61 PF03443.9 KFY04935.1 - 2e-57 194.5 0.4 3.3e-57 193.7 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KFY04935.1 - 4.2e-13 48.6 12.4 4.2e-13 48.6 8.6 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_61 PF03443.9 KFY04936.1 - 3.7e-69 232.8 0.0 4.8e-69 232.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ank_2 PF12796.2 KFY04937.1 - 1.6e-24 86.0 1.4 2.7e-12 46.8 0.1 3.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFY04937.1 - 3.9e-16 58.7 0.6 1.5e-08 34.6 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFY04937.1 - 4.1e-15 55.8 1.6 5.9e-08 33.0 0.3 5.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 KFY04937.1 - 1e-12 47.1 0.3 1.2e-05 24.8 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 KFY04937.1 - 2e-12 46.0 0.3 0.00048 20.1 0.0 4.8 5 0 0 5 5 4 2 Ankyrin repeat TPR_12 PF13424.1 KFY04937.1 - 3.5e-08 33.2 1.2 0.11 12.4 0.1 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat NACHT PF05729.7 KFY04937.1 - 6.8e-06 25.8 0.1 6.2e-05 22.7 0.1 2.4 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KFY04937.1 - 7.5e-05 22.7 0.0 0.00033 20.6 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFY04937.1 - 0.00042 20.4 0.0 0.0042 17.2 0.0 2.7 1 1 1 2 2 2 1 AAA domain MARVEL PF01284.18 KFY04937.1 - 0.0062 16.3 1.5 0.012 15.4 1.1 1.5 1 0 0 1 1 1 1 Membrane-associating domain TPR_2 PF07719.12 KFY04937.1 - 0.033 14.0 0.2 52 4.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA PF00004.24 KFY04937.1 - 0.1 12.8 0.0 0.52 10.5 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ENOD40 PF08247.6 KFY04937.1 - 9.1 6.3 9.3 0.46 10.3 2.0 2.3 2 0 0 2 2 2 0 ENOD40 protein UPF0061 PF02696.9 KFY04939.1 - 3.5e-124 414.7 0.0 5.9e-107 357.9 0.0 2.6 2 1 1 3 3 3 2 Uncharacterized ACR, YdiU/UPF0061 family Ank_2 PF12796.2 KFY04939.1 - 5.7e-26 90.6 4.6 1.8e-13 50.6 0.1 4.2 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFY04939.1 - 2.4e-15 55.4 1.5 0.0025 17.5 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 KFY04939.1 - 4.3e-12 45.8 0.1 0.00011 22.2 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KFY04939.1 - 4.7e-12 46.0 0.1 2.3e-07 31.1 0.0 3.6 3 0 0 3 3 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY04939.1 - 5.5e-08 32.3 1.0 0.39 11.1 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeat NACHT PF05729.7 KFY04939.1 - 0.00046 19.8 0.0 0.0024 17.5 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_10 PF12846.2 KFY04939.1 - 0.0029 17.0 0.0 0.05 13.0 0.0 3.0 3 0 0 3 3 3 1 AAA-like domain AAA_16 PF13191.1 KFY04939.1 - 0.0033 17.4 0.0 0.059 13.3 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KFY04939.1 - 0.004 17.2 0.1 0.035 14.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 KFY04939.1 - 0.0081 16.0 0.0 0.029 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KFY04939.1 - 0.035 14.0 0.0 0.21 11.5 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase ABC_tran PF00005.22 KFY04939.1 - 0.046 14.0 0.0 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 KFY04939.1 - 0.092 13.5 2.5 0.29 11.9 0.0 3.2 3 1 0 3 3 2 0 AAA domain MA3 PF02847.12 KFY04939.1 - 0.15 11.7 0.5 3 7.5 0.1 2.8 2 1 1 3 3 3 0 MA3 domain Aldo_ket_red PF00248.16 KFY04940.1 - 3.7e-52 176.9 0.0 4.3e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family B12-binding PF02310.14 KFY04940.1 - 0.045 13.6 0.0 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 B12 binding domain NAM-associated PF14303.1 KFY04941.1 - 0.81 9.9 5.4 1.5 9.1 3.7 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain GFA PF04828.9 KFY04942.1 - 1.2e-19 70.0 0.0 1.6e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 KFY04942.1 - 0.038 13.2 0.1 0.038 13.2 0.0 2.1 3 0 0 3 3 3 0 zinc-ribbon domain ACBP PF00887.14 KFY04943.1 - 6.2e-31 105.9 0.0 2.1e-30 104.2 0.0 1.8 2 0 0 2 2 2 1 Acyl CoA binding protein Atg14 PF10186.4 KFY04943.1 - 0.0018 17.3 0.5 0.37 9.6 0.0 2.1 2 0 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 PRT_C PF08372.5 KFY04943.1 - 0.02 14.3 0.1 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal WLM PF08325.5 KFY04944.1 - 1e-43 149.3 0.0 1.6e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 KFY04944.1 - 0.0016 18.2 1.1 0.0041 16.9 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function DUF45 SprT-like PF10263.4 KFY04944.1 - 0.0092 15.6 0.4 0.014 15.0 0.0 1.5 2 0 0 2 2 2 1 SprT-like family Peptidase_MA_2 PF13485.1 KFY04944.1 - 0.014 15.4 0.1 0.033 14.2 0.1 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily F-box-like PF12937.2 KFY04945.1 - 3.2e-05 23.5 0.2 3.2e-05 23.5 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KFY04945.1 - 0.07 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 F-box domain Imm15 PF15590.1 KFY04945.1 - 0.13 11.3 0.1 0.31 10.1 0.1 1.6 1 0 0 1 1 1 0 Immunity protein 15 Chromo PF00385.19 KFY04946.1 - 4.2e-09 35.9 0.8 8e-09 35.0 0.5 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mago-bind PF09282.5 KFY04946.1 - 1.5e-05 24.4 0.3 4.8e-05 22.8 0.2 1.9 1 0 0 1 1 1 1 Mago binding TIP49 PF06068.8 KFY04947.1 - 2.6e-174 579.6 4.2 3.1e-174 579.3 2.9 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 KFY04947.1 - 9e-09 34.7 1.3 0.00011 21.3 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 KFY04947.1 - 1.5e-08 34.8 0.2 9.1e-05 22.6 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 KFY04947.1 - 2.4e-06 26.6 0.5 4.8e-06 25.6 0.4 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 KFY04947.1 - 5.9e-05 23.2 0.1 0.06 13.4 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 KFY04947.1 - 8.9e-05 22.5 0.0 0.00059 19.8 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 KFY04947.1 - 0.00011 21.4 0.9 0.0037 16.4 0.3 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KFY04947.1 - 0.00045 20.1 0.0 0.85 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KFY04947.1 - 0.0016 18.1 0.7 0.83 9.3 0.0 3.4 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KFY04947.1 - 0.017 14.5 0.1 0.038 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KFY04947.1 - 0.027 13.9 1.2 0.99 8.8 0.0 2.7 2 1 0 2 2 2 0 FtsK/SpoIIIE family Sigma54_activat PF00158.21 KFY04947.1 - 0.033 13.6 0.0 6 6.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 KFY04947.1 - 0.04 13.6 0.3 0.13 12.0 0.2 1.8 1 1 0 1 1 1 0 Part of AAA domain AAA_11 PF13086.1 KFY04947.1 - 0.1 12.1 0.4 0.2 11.2 0.3 1.5 1 1 0 1 1 1 0 AAA domain HALZ PF02183.13 KFY04948.1 - 0.0085 15.7 2.9 3.9 7.2 0.3 4.0 3 0 0 3 3 3 2 Homeobox associated leucine zipper DUF1664 PF07889.7 KFY04948.1 - 0.049 13.4 28.6 0.11 12.2 1.5 5.7 6 1 1 7 7 7 0 Protein of unknown function (DUF1664) Sugarporin_N PF11471.3 KFY04948.1 - 0.22 11.2 0.0 0.22 11.2 0.0 3.9 4 0 0 4 4 4 0 Maltoporin periplasmic N-terminal extension AAA_13 PF13166.1 KFY04948.1 - 0.43 8.9 36.2 0.046 12.1 4.0 3.8 3 2 1 4 4 4 0 AAA domain LSM14 PF12701.2 KFY04950.1 - 2.2e-34 117.1 0.0 4e-34 116.2 0.0 1.5 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 KFY04950.1 - 1.6e-15 57.4 4.8 6e-15 55.6 3.3 2.1 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.1 KFY04950.1 - 2e-06 27.6 0.0 4.2e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain ER_lumen_recept PF00810.13 KFY04951.1 - 1.2e-53 181.5 11.0 2e-53 180.8 7.6 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF485 PF04341.7 KFY04951.1 - 0.011 15.3 0.1 0.011 15.3 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function, DUF485 PQ-loop PF04193.9 KFY04951.1 - 1.3 8.6 13.7 1.6 8.3 0.2 4.0 4 0 0 4 4 4 0 PQ loop repeat Romo1 PF10247.4 KFY04952.1 - 0.036 14.2 0.0 0.077 13.2 0.0 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 DUF908 PF06012.7 KFY04952.1 - 0.25 10.5 0.7 0.37 10.0 0.5 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) TMEM154 PF15102.1 KFY04952.1 - 0.49 10.0 2.5 1.9 8.1 1.8 1.9 1 1 0 1 1 1 0 TMEM154 protein family ORC6 PF05460.8 KFY04952.1 - 6.1 5.8 12.1 8 5.4 8.4 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) KAR9 PF08580.5 KFY04952.1 - 9.6 4.3 10.6 12 3.9 7.4 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 CAP59_mtransfer PF11735.3 KFY04953.1 - 5.3e-64 215.7 0.0 7e-64 215.3 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Glyco_tranf_2_3 PF13641.1 KFY04953.1 - 0.00049 19.9 0.0 0.00074 19.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 ATP-synt_ab PF00006.20 KFY04954.1 - 8.5e-62 208.4 0.0 1.3e-61 207.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KFY04954.1 - 3.1e-25 88.8 0.6 5.3e-25 88.0 0.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KFY04954.1 - 6.1e-24 84.0 0.4 1.7e-23 82.6 0.3 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_25 PF13481.1 KFY04954.1 - 0.00071 19.0 0.2 0.014 14.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 KFY04954.1 - 0.0069 16.5 0.1 0.44 10.7 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KFY04954.1 - 0.0072 16.0 0.0 0.017 14.8 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 KFY04954.1 - 0.01 15.5 0.2 0.93 9.1 0.0 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 KFY04954.1 - 0.011 14.8 0.1 0.019 14.0 0.1 1.4 1 0 0 1 1 1 0 KaiC DUF258 PF03193.11 KFY04954.1 - 0.013 14.7 0.2 0.024 13.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 KFY04954.1 - 0.029 14.0 0.2 0.077 12.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 KFY04954.1 - 0.047 13.8 0.0 0.13 12.4 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_16 PF13191.1 KFY04954.1 - 0.062 13.2 0.3 0.33 10.9 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain EKR PF10371.4 KFY04954.1 - 0.077 12.5 0.0 0.28 10.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function AAA_22 PF13401.1 KFY04954.1 - 0.14 12.2 0.0 0.59 10.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KFY04954.1 - 0.21 10.4 0.8 0.65 8.7 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain Alpha-amylase_C PF02806.13 KFY04955.1 - 2e-24 85.5 0.2 5.6e-24 84.0 0.0 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.13 KFY04955.1 - 3.3e-19 68.7 0.1 9.8e-19 67.1 0.1 1.9 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.19 KFY04955.1 - 2.2e-18 66.7 0.2 1.9e-14 53.8 0.1 2.7 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Rho_Binding PF08912.6 KFY04955.1 - 0.044 14.0 0.0 14 6.0 0.0 2.3 2 0 0 2 2 2 0 Rho Binding AAA_2 PF07724.9 KFY04956.1 - 3.4e-37 127.9 0.0 9.3e-37 126.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KFY04956.1 - 4.9e-12 46.1 0.0 8.4e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KFY04956.1 - 4.3e-08 32.9 0.0 1e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 KFY04956.1 - 5.6e-06 26.1 0.0 1.2e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KFY04956.1 - 1.6e-05 25.6 0.0 5.3e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KFY04956.1 - 0.00013 22.1 0.1 0.0018 18.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KFY04956.1 - 0.0015 17.9 0.8 0.0026 17.2 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 KFY04956.1 - 0.0032 17.4 0.0 0.0082 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 KFY04956.1 - 0.004 17.0 0.0 0.008 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFY04956.1 - 0.0088 15.4 0.0 0.02 14.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain MCM PF00493.18 KFY04956.1 - 0.015 14.0 0.1 0.015 14.0 0.1 2.1 2 1 0 2 2 2 0 MCM2/3/5 family AAA_18 PF13238.1 KFY04956.1 - 0.02 15.1 0.2 0.091 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KFY04956.1 - 0.031 13.7 0.0 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.16 KFY04956.1 - 0.054 12.6 0.1 4.5 6.3 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KFY04956.1 - 0.063 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KFY04956.1 - 0.065 12.8 1.6 0.19 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KFY04956.1 - 0.073 12.9 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KFY04956.1 - 0.074 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.13 KFY04956.1 - 0.085 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RuvB_N PF05496.7 KFY04956.1 - 0.094 11.7 0.2 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 KFY04956.1 - 0.099 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_6 PF12774.2 KFY04956.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region D1 RNA_helicase PF00910.17 KFY04956.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase COX4 PF02936.9 KFY04957.1 - 1.3e-49 167.5 0.0 1.8e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1104 PF06518.6 KFY04957.1 - 0.13 12.3 0.1 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) DUF4370 PF14290.1 KFY04957.1 - 0.37 10.2 2.0 0.7 9.3 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4370) Gp_dh_C PF02800.15 KFY04958.1 - 9.4e-73 242.8 0.9 1.5e-72 242.1 0.6 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KFY04958.1 - 4.5e-59 198.7 0.7 7.4e-59 198.0 0.1 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 KFY04958.1 - 0.067 13.1 0.4 0.53 10.2 0.0 2.5 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 KFY04958.1 - 0.078 12.1 0.0 0.19 10.8 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Molybdopterin PF00384.17 KFY04959.1 - 3.5e-41 141.3 0.0 2.9e-39 135.0 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 PF10588.4 KFY04959.1 - 1.6e-19 68.8 0.1 4.8e-19 67.2 0.1 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 PF13510.1 KFY04959.1 - 9.7e-19 66.9 0.2 2.9e-18 65.4 0.1 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer2 PF00111.22 KFY04959.1 - 7.5e-08 32.0 0.4 7.5e-08 32.0 0.3 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 KFY04959.1 - 0.012 15.3 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4_19 PF06902.6 KFY04959.1 - 2.1 8.2 5.8 5.7 6.8 1.3 3.1 2 1 0 2 2 2 0 Divergent 4Fe-4S mono-cluster OTT_1508_deam PF14441.1 KFY04962.1 - 6.3e-09 35.7 0.1 1.2e-08 34.8 0.1 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase TraI_2 PF07514.6 KFY04962.1 - 0.021 13.6 0.2 0.04 12.6 0.1 1.5 1 0 0 1 1 1 0 Putative helicase mRNA_cap_enzyme PF01331.14 KFY04964.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 mRNA capping enzyme, catalytic domain MFS_1 PF07690.11 KFY04967.1 - 5.2e-34 117.5 26.7 5.2e-34 117.5 18.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily AAA_25 PF13481.1 KFY04967.1 - 0.027 13.8 0.0 0.05 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF1049 PF06305.6 KFY04967.1 - 2.1 7.8 5.8 18 4.9 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Glyco_hydro_88 PF07470.8 KFY04969.1 - 9.5e-87 291.1 2.6 1.1e-86 290.9 1.8 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 KFY04969.1 - 0.059 11.6 0.3 0.25 9.5 0.2 1.8 1 1 0 1 1 1 0 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_76 PF03663.9 KFY04969.1 - 0.48 9.7 7.7 0.41 9.9 0.6 2.5 1 1 2 3 3 3 0 Glycosyl hydrolase family 76 CBM-like PF14683.1 KFY04970.1 - 1e-41 142.3 0.0 1.8e-41 141.6 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 KFY04970.1 - 1e-23 83.2 0.6 3.9e-23 81.3 0.1 2.4 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 KFY04970.1 - 2.5e-08 33.8 0.2 2.2e-05 24.4 0.0 2.6 2 0 0 2 2 2 2 Carboxypeptidase regulatory-like domain DUF2012 PF09430.5 KFY04970.1 - 0.062 13.1 0.0 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2012) Ank_2 PF12796.2 KFY04974.1 - 2.6e-69 229.5 18.8 1.5e-19 70.1 0.1 4.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 KFY04974.1 - 2.6e-58 191.0 16.4 6.5e-08 32.0 0.2 9.7 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.1 KFY04974.1 - 6.6e-45 150.7 20.1 4.6e-10 39.7 0.0 7.4 2 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY04974.1 - 1.5e-41 136.2 14.2 4.3e-06 26.4 0.1 9.9 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.1 KFY04974.1 - 3.4e-31 106.5 14.9 2.8e-07 30.5 0.1 7.2 4 2 3 7 7 7 6 Ankyrin repeats (many copies) NACHT PF05729.7 KFY04974.1 - 3.1e-09 36.7 0.0 7.3e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KFY04974.1 - 0.00051 20.0 0.0 0.0017 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KFY04974.1 - 0.0017 18.5 0.6 0.014 15.5 0.0 2.7 4 0 0 4 4 4 1 AAA domain Ribosomal_S6 PF01250.12 KFY04974.1 - 0.033 14.0 0.0 3.1 7.7 0.0 3.2 3 0 0 3 3 3 0 Ribosomal protein S6 UCH_1 PF13423.1 KFY04975.1 - 1e-55 189.2 0.0 1.5e-55 188.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 KFY04975.1 - 3.5e-21 76.1 0.0 6.2e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 KFY04975.1 - 1.1e-07 31.3 0.0 2.4e-06 26.8 0.0 2.6 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase GTP_EFTU PF00009.22 KFY04976.1 - 8.8e-44 149.1 0.0 1.9e-43 148.0 0.0 1.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KFY04976.1 - 1.2e-20 73.4 0.1 4.1e-20 71.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KFY04976.1 - 2.4e-05 24.3 0.4 5.9e-05 23.1 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KFY04976.1 - 2.9e-05 23.9 0.0 7.5e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KFY04976.1 - 0.015 13.9 2.3 0.026 13.2 1.6 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Ran-binding PF05508.6 KFY04977.1 - 4.1e-103 344.4 0.0 5.5e-103 344.0 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein TRAUB PF08164.7 KFY04978.1 - 6.8e-31 106.2 0.5 1.1e-29 102.3 0.0 2.8 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 KFY04978.1 - 7.4e-26 90.8 7.8 7.4e-26 90.8 5.4 2.6 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor ParA PF10609.4 KFY04979.1 - 5.7e-34 115.8 0.2 1.3e-33 114.7 0.1 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KFY04979.1 - 1.6e-14 53.7 0.0 2.2e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KFY04979.1 - 1.2e-08 35.0 0.1 9.7e-08 32.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 KFY04979.1 - 2.4e-05 23.5 0.0 3.5e-05 23.0 0.0 1.3 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 KFY04979.1 - 0.00058 19.0 0.8 0.013 14.5 0.3 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 KFY04979.1 - 0.0026 17.2 0.1 0.0074 15.7 0.1 1.9 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 KFY04979.1 - 0.017 14.3 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.1 KFY04979.1 - 0.017 14.7 0.1 0.39 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KFY04979.1 - 0.13 12.0 1.0 7.5 6.3 0.0 2.9 4 0 0 4 4 4 0 Part of AAA domain 3HCDH_N PF02737.13 KFY04982.1 - 1e-30 106.7 0.0 1.2e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KFY04982.1 - 4.9e-08 33.2 0.0 9.2e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KFY04982.1 - 0.078 12.8 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 KFY04982.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Fungal_trans PF04082.13 KFY04983.1 - 8.5e-07 28.1 2.0 2.2e-06 26.7 0.8 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY04983.1 - 0.0015 18.3 11.8 0.0028 17.5 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Histidinol_dh PF00815.15 KFY04984.1 - 1.2e-113 379.9 0.1 1.5e-113 379.6 0.1 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Mito_carr PF00153.22 KFY04985.1 - 1.5e-55 184.8 2.9 9.2e-18 63.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.11 KFY04986.1 - 1.9e-36 125.5 30.8 2.6e-36 125.0 21.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3505 PF12013.3 KFY04987.1 - 1.4e-17 63.8 0.3 2e-17 63.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3505) zf-H2C2_5 PF13909.1 KFY04987.1 - 0.032 14.4 6.2 0.72 10.2 1.5 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain YvrJ PF12841.2 KFY04988.1 - 0.28 10.4 0.1 0.28 10.4 0.1 1.7 2 0 0 2 2 2 0 YvrJ protein family DNA_pol_A_exo1 PF01612.15 KFY04991.1 - 3e-39 134.3 0.1 4.3e-39 133.7 0.1 1.2 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 KFY04991.1 - 1.6e-25 89.1 0.0 3.6e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 KFY04991.1 - 2.8e-14 52.5 0.0 9.6e-14 50.8 0.0 2.0 1 0 0 1 1 1 1 HRDC domain DUF2833 PF11090.3 KFY04991.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) UPF0203 PF05254.7 KFY04992.1 - 4.4e-28 96.9 0.3 5.3e-28 96.6 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.8 KFY04992.1 - 0.00094 19.1 0.2 0.0022 17.9 0.1 1.6 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 KFY04992.1 - 0.002 17.8 2.1 0.093 12.5 0.1 2.3 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 KFY04992.1 - 0.21 11.5 1.6 6.2 6.8 1.2 2.1 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein Gpi1 PF05024.10 KFY04993.1 - 3.7e-65 219.1 9.0 3.7e-65 219.1 6.2 1.6 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) 7tm_1 PF00001.16 KFY04993.1 - 0.0079 15.3 0.6 0.0079 15.3 0.4 1.8 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) IDO PF01231.13 KFY04998.1 - 4.3e-76 256.0 0.0 4.8e-76 255.8 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Cgr1 PF03879.9 KFY05004.1 - 1e-33 115.7 29.9 1.2e-33 115.5 20.7 1.0 1 0 0 1 1 1 1 Cgr1 family Ndufs5 PF10200.4 KFY05004.1 - 0.24 11.4 10.5 0.43 10.6 6.5 1.8 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF4612 PF15389.1 KFY05004.1 - 0.62 10.6 6.3 0.79 10.3 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) GAGA_bind PF06217.7 KFY05004.1 - 1 9.2 9.6 1.2 9.0 6.7 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Silic_transp PF03842.8 KFY05004.1 - 1.9 6.4 4.8 2.1 6.3 3.3 1.0 1 0 0 1 1 1 0 Silicon transporter Vfa1 PF08432.5 KFY05004.1 - 3 7.8 14.0 3.7 7.5 9.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Mito_carr PF00153.22 KFY05005.1 - 2.8e-63 209.6 0.4 8.9e-21 73.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TspO_MBR PF03073.10 KFY05006.1 - 3.3e-39 133.7 1.5 4.2e-39 133.4 1.0 1.1 1 0 0 1 1 1 1 TspO/MBR family Menin PF05053.8 KFY05010.1 - 0.21 9.7 7.1 0.3 9.2 4.9 1.2 1 0 0 1 1 1 0 Menin Rad4 PF03835.10 KFY05011.1 - 4.9e-31 107.0 0.4 1.4e-30 105.5 0.3 1.8 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KFY05011.1 - 2.8e-27 94.2 0.0 5.4e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 KFY05011.1 - 8.4e-14 50.8 0.0 1.9e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KFY05011.1 - 1.2e-11 44.7 0.2 9.3e-11 41.8 0.0 2.6 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KFY05011.1 - 0.018 15.2 0.0 0.13 12.4 0.0 2.3 1 1 0 1 1 1 0 Transglutaminase-like superfamily Adeno_terminal PF02459.10 KFY05011.1 - 0.38 8.8 2.6 0.62 8.1 1.8 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein p450 PF00067.17 KFY05012.1 - 2.1e-53 181.4 0.0 2.7e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PEX11 PF05648.9 KFY05015.1 - 1.1e-71 240.7 0.0 1.2e-71 240.5 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF2805 PF10985.3 KFY05015.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) TPT PF03151.11 KFY05016.1 - 7.7e-28 97.0 10.4 7.7e-28 97.0 7.2 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KFY05016.1 - 4.5e-07 29.0 19.7 1.1e-06 27.8 13.7 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 KFY05016.1 - 0.22 11.5 33.0 0.2 11.7 7.6 3.2 3 0 0 3 3 3 0 EamA-like transporter family MFS_1 PF07690.11 KFY05017.1 - 7e-41 140.1 49.5 7e-41 140.1 34.3 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY05017.1 - 7e-08 31.4 13.9 7e-08 31.4 9.6 3.8 2 1 1 3 3 3 2 Sugar (and other) transporter Aldo_ket_red PF00248.16 KFY05018.1 - 1.4e-49 168.4 0.0 1.8e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4336 PF14234.1 KFY05019.1 - 1.8e-13 50.3 0.0 1.4e-08 34.2 0.0 2.3 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) Fungal_trans_2 PF11951.3 KFY05020.1 - 1.4e-08 33.7 1.3 2.4e-08 33.0 0.9 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY05020.1 - 0.00011 21.9 8.6 0.00026 20.8 6.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_17 PF04724.8 KFY05021.1 - 3.9e-43 147.8 4.9 5.4e-43 147.3 3.4 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 Colicin_immun PF09204.5 KFY05023.1 - 0.091 12.8 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial self-protective colicin-like immunity Shisa PF13908.1 KFY05024.1 - 4e-05 23.8 0.1 7.5e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator SKG6 PF08693.5 KFY05024.1 - 0.0035 16.6 5.6 0.0035 16.6 3.9 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF2668 PF10873.3 KFY05024.1 - 0.025 14.7 1.9 0.053 13.6 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) RCR PF12273.3 KFY05024.1 - 0.027 15.0 0.1 0.068 13.7 0.0 1.7 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Syndecan PF01034.15 KFY05024.1 - 0.081 12.5 0.3 0.16 11.6 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain Rifin_STEVOR PF02009.11 KFY05024.1 - 0.095 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family Herpes_gE PF02480.11 KFY05024.1 - 0.14 10.4 0.0 0.19 9.9 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E VSP PF03302.8 KFY05024.1 - 0.14 10.7 0.3 0.2 10.2 0.2 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein PGG PF13962.1 KFY05025.1 - 0.049 13.2 0.1 0.055 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function Lactamase_B_2 PF12706.2 KFY05026.1 - 4.8e-10 39.3 0.0 6.6e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain bZIP_1 PF00170.16 KFY05027.1 - 2.4e-05 24.2 9.2 3.8e-05 23.5 6.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KFY05027.1 - 0.0004 20.1 5.1 0.00061 19.5 3.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 KFY05027.1 - 1.9 8.8 9.4 0.38 11.0 3.9 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor PAS_6 PF08348.6 KFY05028.1 - 0.05 13.1 0.1 0.17 11.4 0.0 1.8 1 1 1 2 2 2 0 YheO-like PAS domain HALZ PF02183.13 KFY05029.1 - 0.00091 18.8 2.9 0.0013 18.3 2.0 1.2 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_2 PF07716.10 KFY05029.1 - 0.0055 16.5 4.8 0.0094 15.7 3.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper DUF4600 PF15372.1 KFY05029.1 - 0.014 15.5 0.1 0.017 15.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) MAD PF05557.8 KFY05029.1 - 0.02 13.0 0.6 0.024 12.7 0.4 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF4618 PF15397.1 KFY05029.1 - 0.024 13.9 0.5 0.029 13.7 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) COG7 PF10191.4 KFY05029.1 - 0.029 12.2 0.1 0.033 12.1 0.0 1.0 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) DUF972 PF06156.8 KFY05029.1 - 0.035 14.4 0.5 0.046 14.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Pilin PF00114.14 KFY05029.1 - 0.077 13.7 0.2 0.091 13.4 0.1 1.2 1 0 0 1 1 1 0 Pilin (bacterial filament) bZIP_1 PF00170.16 KFY05029.1 - 0.084 12.8 3.2 0.12 12.3 2.2 1.2 1 0 0 1 1 1 0 bZIP transcription factor DUF2381 PF09544.5 KFY05029.1 - 0.11 11.5 0.1 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) DivIC PF04977.10 KFY05029.1 - 0.19 11.2 2.0 0.29 10.6 1.4 1.3 1 0 0 1 1 1 0 Septum formation initiator Rab5-bind PF09311.6 KFY05029.1 - 0.31 10.9 5.2 0.4 10.5 3.6 1.1 1 0 0 1 1 1 0 Rabaptin-like protein FIVAR PF07554.8 KFY05030.1 - 0.22 11.7 0.3 0.22 11.7 0.2 2.1 3 0 0 3 3 3 0 Uncharacterised Sugar-binding Domain Zn_clus PF00172.13 KFY05031.1 - 0.00074 19.3 12.6 0.0016 18.2 8.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.6 KFY05034.1 - 2.5e-10 40.6 0.0 5e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) E1-N PF14463.1 KFY05034.1 - 0.015 14.9 0.5 0.026 14.1 0.4 1.3 1 0 0 1 1 1 0 E1 N-terminal domain Glutaredoxin PF00462.19 KFY05034.1 - 0.018 15.0 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin DIOX_N PF14226.1 KFY05035.1 - 2.4e-24 86.1 0.0 3.6e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KFY05035.1 - 1.8e-19 69.8 0.0 3.7e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 KFY05036.1 - 2.8e-16 59.2 23.7 3.9e-16 58.7 16.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 KFY05036.1 - 0.015 13.3 3.1 0.12 10.3 0.1 2.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SYCE1 PF15233.1 KFY05037.1 - 0.13 12.1 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 LSM PF01423.17 KFY05042.1 - 3e-19 68.3 0.7 3.5e-19 68.1 0.5 1.0 1 0 0 1 1 1 1 LSM domain Thiolase_N PF00108.18 KFY05043.1 - 1.9e-101 338.4 1.2 2.4e-101 338.1 0.4 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KFY05043.1 - 1.5e-46 156.8 1.5 1.5e-46 156.8 1.1 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KFY05043.1 - 1.4e-05 24.7 1.1 2.3e-05 23.9 0.4 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KFY05043.1 - 0.3 10.7 2.3 1.1 8.9 0.0 2.5 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GTP_EFTU PF00009.22 KFY05044.1 - 6.8e-43 146.2 0.0 1e-42 145.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KFY05044.1 - 2.2e-24 85.2 0.0 6e-24 83.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 KFY05044.1 - 4e-17 61.8 0.0 1.1e-16 60.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KFY05044.1 - 1.6e-09 37.7 0.0 4.7e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KFY05044.1 - 1.1e-06 28.4 0.0 2.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 KFY05044.1 - 1.2e-05 25.2 0.1 2.3e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KFY05044.1 - 0.0026 18.2 0.0 0.0076 16.7 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KFY05044.1 - 0.05 12.8 0.1 0.16 11.1 0.1 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ADH_N PF08240.7 KFY05045.1 - 5.2e-27 93.7 2.5 5.5e-27 93.6 0.8 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 KFY05045.1 - 1.9e-07 30.5 0.9 4.1e-07 29.5 0.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 KFY05045.1 - 1.7e-05 24.3 0.0 0.0065 16.0 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Thioredoxin_4 PF13462.1 KFY05046.1 - 7.6e-07 29.2 0.0 2.1e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin DUF3844 PF12955.2 KFY05047.1 - 7.9e-31 106.2 2.9 7.9e-31 106.2 2.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) GNAT_acetyltr_2 PF13718.1 KFY05048.1 - 2.5e-78 261.9 0.0 4.6e-78 261.0 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 KFY05048.1 - 1.6e-65 220.0 0.0 4.8e-65 218.4 0.0 1.8 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 KFY05048.1 - 2e-40 136.3 0.0 4.8e-40 135.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 KFY05048.1 - 2.8e-35 120.4 0.3 8.3e-35 118.9 0.2 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 KFY05048.1 - 0.053 13.6 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Histone PF00125.19 KFY05048.1 - 0.067 13.3 0.0 0.23 11.5 0.0 1.9 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Glyco_transf_90 PF05686.7 KFY05049.1 - 0.051 12.2 0.2 9.1 4.8 0.0 2.7 3 0 0 3 3 3 0 Glycosyl transferase family 90 UpxZ PF06603.6 KFY05049.1 - 0.18 11.8 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists Lipase_3 PF01764.20 KFY05050.1 - 2.9e-32 111.2 0.0 4.1e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KFY05050.1 - 0.0031 17.2 0.1 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KFY05050.1 - 0.0053 17.0 0.1 0.0077 16.4 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 KFY05050.1 - 0.011 15.6 0.2 0.015 15.1 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cellulase PF00150.13 KFY05051.1 - 1.5e-48 165.4 0.0 2.2e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NmrA PF05368.8 KFY05051.1 - 9.7e-09 34.8 0.0 0.002 17.4 0.0 2.4 2 0 0 2 2 2 2 NmrA-like family XLF PF09302.6 KFY05052.1 - 1.6e-25 89.8 0.1 1.6e-25 89.8 0.1 2.0 2 0 0 2 2 2 1 XLF (XRCC4-like factor) DUF3807 PF12720.2 KFY05053.1 - 7.5e-36 123.8 4.9 9.2e-36 123.5 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) Fork_head PF00250.13 KFY05055.1 - 4.2e-14 52.3 0.0 9.6e-14 51.2 0.0 1.6 1 0 0 1 1 1 1 Fork head domain Cactin_mid PF10312.4 KFY05056.1 - 4.6e-65 218.4 8.5 7.5e-65 217.7 5.9 1.3 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 KFY05056.1 - 1.6e-55 186.0 5.5 2.5e-55 185.3 3.8 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein TPR_20 PF14561.1 KFY05056.1 - 0.011 15.8 0.1 0.028 14.5 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1087 PF06465.8 KFY05056.1 - 0.029 14.2 3.8 0.7 9.8 0.4 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) DUF1662 PF07878.6 KFY05056.1 - 0.12 12.1 0.3 0.39 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1662) YolD PF08863.5 KFY05056.1 - 0.2 11.5 3.2 0.2 11.5 0.1 2.3 2 1 0 2 2 2 0 YolD-like protein Atg14 PF10186.4 KFY05057.1 - 9.3e-19 67.4 0.8 2.5e-18 66.0 0.5 1.7 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 KFY05057.1 - 1.5e-09 37.3 0.0 4.5e-09 35.8 0.0 1.7 2 0 0 2 2 2 1 Autophagy protein Apg6 CM_2 PF01817.16 KFY05057.1 - 0.32 11.1 5.9 0.086 12.9 0.7 2.3 1 1 1 2 2 2 0 Chorismate mutase type II SRF-TF PF00319.13 KFY05058.1 - 1.2e-25 88.4 0.2 1.6e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Dimer_Tnp_hAT PF05699.9 KFY05060.1 - 2.7e-15 55.7 0.0 4.6e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ATG11 PF10377.4 KFY05062.1 - 3.1e-37 127.3 0.2 1.5e-36 125.1 0.0 2.4 2 0 0 2 2 2 1 Autophagy-related protein 11 APG17 PF04108.7 KFY05062.1 - 5.4e-05 22.1 0.2 5.4e-05 22.1 0.1 5.7 3 2 2 5 5 5 1 Autophagy protein Apg17 Cleaved_Adhesin PF07675.6 KFY05062.1 - 0.0018 17.9 0.0 0.0038 16.8 0.0 1.5 1 0 0 1 1 1 1 Cleaved Adhesin Domain Tropomyosin PF00261.15 KFY05062.1 - 0.0033 16.5 17.2 0.0033 16.5 11.9 5.4 3 1 2 5 5 5 1 Tropomyosin CENP-H PF05837.7 KFY05063.1 - 2.3e-27 95.2 4.1 1.7e-24 85.9 0.8 2.1 2 0 0 2 2 2 2 Centromere protein H (CENP-H) Adhes-Ig_like PF09085.5 KFY05063.1 - 0.038 13.8 0.6 0.2 11.5 0.1 2.0 2 0 0 2 2 2 0 Adhesion molecule, immunoglobulin-like TSC22 PF01166.13 KFY05063.1 - 0.039 13.9 0.7 4.4 7.3 0.3 2.9 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4482 PF14818.1 KFY05063.1 - 0.067 13.8 3.6 3.2 8.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) DUF972 PF06156.8 KFY05063.1 - 0.91 9.9 5.5 19 5.6 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Nop52 PF05997.7 KFY05064.1 - 3.7e-56 189.9 0.0 4.2e-56 189.7 0.0 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 TAN PF11640.3 KFY05064.1 - 0.039 13.6 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair DAGK_cat PF00781.19 KFY05065.1 - 1.8e-23 82.4 0.0 2.9e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Adaptin_N PF01602.15 KFY05066.1 - 1.3e-96 324.0 9.2 2.3e-96 323.1 6.4 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.7 KFY05066.1 - 3.1e-63 211.6 1.8 6.4e-63 210.6 1.3 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.1 KFY05066.1 - 8.4e-63 209.8 0.0 2.7e-62 208.2 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.1 KFY05066.1 - 2.6e-11 43.6 7.9 1.3e-06 28.5 0.1 4.2 1 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.2 KFY05066.1 - 0.00029 20.7 10.4 0.0089 15.8 0.0 3.9 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KFY05066.1 - 0.00065 19.5 1.9 0.45 10.7 0.0 4.0 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 KFY05066.1 - 0.022 15.2 5.3 0.25 11.8 0.0 4.4 5 1 1 6 6 6 0 HEAT-like repeat Vac_ImportDeg PF09783.4 KFY05067.1 - 5e-69 231.3 0.4 7.6e-69 230.7 0.3 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.9 KFY05067.1 - 3.2e-59 198.7 0.3 8.1e-59 197.4 0.1 1.6 2 0 0 2 2 2 1 Mago nashi protein Alk_phosphatase PF00245.15 KFY05070.1 - 2.5e-65 220.8 0.2 5.9e-65 219.5 0.1 1.6 1 1 0 1 1 1 1 Alkaline phosphatase Phosphodiest PF01663.17 KFY05070.1 - 7.8e-07 28.7 0.2 1.4e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KFY05070.1 - 4.2e-06 26.1 0.1 8.2e-06 25.2 0.1 1.5 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 KFY05070.1 - 0.0012 17.3 1.1 0.0014 17.1 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF1501 PF07394.7 KFY05070.1 - 0.067 12.0 0.1 0.12 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Cellulase PF00150.13 KFY05071.1 - 3.4e-14 52.6 0.4 5.8e-14 51.9 0.3 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FAD_binding_4 PF01565.18 KFY05073.1 - 5.4e-23 81.0 0.1 1.2e-22 79.9 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain Na_Ca_ex PF01699.19 KFY05074.1 - 0.0097 15.5 2.9 0.028 14.0 0.7 2.2 1 1 0 2 2 2 1 Sodium/calcium exchanger protein DUF389 PF04087.9 KFY05074.1 - 0.082 12.8 4.0 0.079 12.9 1.3 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF389) DUF4396 PF14342.1 KFY05074.1 - 0.094 12.8 5.9 2.2 8.3 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4396) Asp PF00026.18 KFY05075.1 - 3.9e-64 216.8 1.7 6e-64 216.2 1.2 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KFY05075.1 - 1.6e-06 28.1 0.0 9.7e-06 25.6 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KFY05075.1 - 1.1e-05 25.0 0.0 3.3e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KFY05075.1 - 0.054 13.9 0.2 9.7 6.7 0.0 2.7 2 0 0 2 2 2 0 Aspartyl protease SCO1-SenC PF02630.9 KFY05076.1 - 4.3e-60 202.2 0.0 8e-60 201.4 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 KFY05076.1 - 3.6e-05 23.4 0.0 0.00032 20.3 0.0 2.2 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.1 KFY05076.1 - 0.027 14.5 0.0 0.068 13.2 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like Glyco_hydro_3 PF00933.16 KFY05077.1 - 1.2e-87 293.7 0.0 1.7e-87 293.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KFY05077.1 - 3.1e-61 206.7 0.4 5.8e-61 205.8 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KFY05077.1 - 4.2e-27 93.8 0.1 7.9e-27 93.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_88 PF07470.8 KFY05077.1 - 8.9e-27 94.0 0.0 1.5e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Toxin_8 PF07365.7 KFY05077.1 - 1.9 8.5 6.9 1.8 8.6 1.0 2.7 2 0 0 2 2 2 0 Alpha conotoxin precursor F-box-like PF12937.2 KFY05081.1 - 2.3e-10 40.0 0.3 5.9e-10 38.7 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KFY05081.1 - 0.00022 20.7 0.5 0.00066 19.2 0.1 2.0 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.2 KFY05081.1 - 0.49 10.0 5.1 4.9 6.8 1.5 3.6 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Hydrolase_6 PF13344.1 KFY05082.1 - 4.2e-21 74.7 0.0 9.8e-21 73.5 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KFY05082.1 - 2.2e-15 56.1 0.0 6.2e-15 54.6 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KFY05082.1 - 5e-05 23.8 0.0 1.1 9.5 0.0 3.2 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase SIP1 PF04938.7 KFY05083.1 - 6.1e-06 25.7 0.0 3.8e-05 23.1 0.0 2.2 2 1 0 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) ABC_tran PF00005.22 KFY05084.1 - 1.2e-17 64.5 0.1 2.5e-17 63.4 0.1 1.6 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 KFY05084.1 - 0.0019 17.3 0.0 0.0049 16.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KFY05084.1 - 0.0045 16.4 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 KFY05084.1 - 0.0046 16.8 0.1 0.068 13.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 KFY05084.1 - 0.0096 16.0 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KFY05084.1 - 0.011 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 KFY05084.1 - 0.016 15.1 0.2 0.029 14.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KFY05084.1 - 0.029 14.0 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 KFY05084.1 - 0.03 15.1 0.0 0.071 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KFY05084.1 - 0.039 13.6 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 KFY05084.1 - 0.045 14.0 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KFY05084.1 - 0.056 13.4 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 KFY05084.1 - 0.082 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KFY05084.1 - 0.085 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 KFY05084.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 KFY05084.1 - 0.15 11.6 0.1 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 KFY05084.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KFY05084.1 - 0.17 12.1 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 KFY05084.1 - 0.2 10.6 0.0 0.34 9.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KFY05084.1 - 0.2 11.1 0.1 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Aminotran_1_2 PF00155.16 KFY05085.1 - 3.4e-39 134.8 0.0 7.4e-39 133.7 0.0 1.5 1 1 1 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KFY05085.1 - 1.6e-06 26.6 0.0 2.7e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.2 KFY05085.1 - 2e-06 26.6 0.0 2.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.16 KFY05085.1 - 2.1e-06 27.1 0.0 4e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KFY05085.1 - 6.7e-06 25.0 0.0 1e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Alliinase_C PF04864.8 KFY05085.1 - 0.00079 18.1 0.1 0.0019 16.9 0.1 1.6 1 1 0 1 1 1 1 Allinase DegT_DnrJ_EryC1 PF01041.12 KFY05085.1 - 0.0018 17.3 0.0 0.003 16.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DnaB_2 PF07261.6 KFY05085.1 - 0.023 14.3 0.1 20 4.8 0.0 3.3 3 0 0 3 3 3 0 Replication initiation and membrane attachment RNase_Zc3h12a PF11977.3 KFY05085.1 - 0.078 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain SET PF00856.23 KFY05086.1 - 9.8e-11 42.2 0.2 4.2e-10 40.1 0.2 1.9 1 1 0 1 1 1 1 SET domain NGP1NT PF08153.7 KFY05088.1 - 5e-45 152.6 0.0 8.4e-45 151.8 0.0 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 KFY05088.1 - 4.3e-19 68.5 0.0 6.6e-15 55.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KFY05088.1 - 0.00037 19.8 0.0 0.0019 17.4 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 KFY05088.1 - 0.0014 17.9 0.0 0.12 11.6 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KFY05088.1 - 0.003 17.0 0.0 0.29 10.5 0.0 3.0 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KFY05088.1 - 0.0031 17.3 5.6 0.54 10.0 0.0 4.1 3 1 1 4 4 4 1 Dynamin family DUF258 PF03193.11 KFY05088.1 - 0.0092 15.1 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 HBS1_N PF08938.5 KFY05088.1 - 0.31 11.1 12.5 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 HBS1 N-terminus Nop14 PF04147.7 KFY05088.1 - 0.69 7.7 25.3 0.9 7.3 17.5 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KFY05088.1 - 1.2 7.4 19.1 2 6.8 13.2 1.2 1 0 0 1 1 1 0 Daxx Family Sigma70_ner PF04546.8 KFY05088.1 - 2.9 7.4 13.1 6.3 6.3 9.1 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region AT_hook PF02178.14 KFY05089.1 - 6.2 6.8 14.9 0.16 11.6 3.4 3.8 2 0 0 2 2 2 0 AT hook motif AAA PF00004.24 KFY05091.1 - 9.4e-20 71.1 0.0 5.8e-17 62.1 0.0 3.2 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFY05091.1 - 3.5e-10 40.1 0.0 4.7e-05 23.5 0.0 3.3 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 KFY05091.1 - 8.9e-10 38.4 0.0 1.3e-06 28.2 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.1 KFY05091.1 - 3.7e-08 34.2 0.1 0.0023 18.7 0.0 4.0 4 0 0 4 4 2 2 AAA domain AAA_18 PF13238.1 KFY05091.1 - 4.2e-07 30.3 0.0 0.017 15.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFY05091.1 - 4.3e-07 30.0 1.1 0.12 12.3 0.0 3.8 3 1 0 3 3 3 2 AAA ATPase domain RNA_helicase PF00910.17 KFY05091.1 - 3.4e-05 23.9 0.2 0.051 13.7 0.1 2.8 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 KFY05091.1 - 0.00023 21.0 0.0 1.7 8.5 0.0 3.3 3 0 0 3 3 2 2 AAA domain Ank PF00023.25 KFY05091.1 - 0.00035 20.2 0.0 1 9.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat AAA_5 PF07728.9 KFY05091.1 - 0.0012 18.5 0.2 0.19 11.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KFY05091.1 - 0.0015 18.1 0.1 0.085 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KFY05091.1 - 0.0015 18.2 0.0 2.7 7.7 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain NB-ARC PF00931.17 KFY05091.1 - 0.0018 17.1 0.1 0.34 9.7 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.22 KFY05091.1 - 0.0028 17.9 0.1 0.056 13.7 0.0 3.0 3 0 0 3 3 3 1 ABC transporter Ank_2 PF12796.2 KFY05091.1 - 0.0031 17.8 0.0 0.01 16.1 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) KaiC PF06745.8 KFY05091.1 - 0.0044 16.1 2.1 0.43 9.6 0.2 3.1 3 0 0 3 3 3 1 KaiC Transposase_mut PF00872.13 KFY05091.1 - 0.0047 15.5 0.4 0.0079 14.7 0.3 1.3 1 0 0 1 1 1 1 Transposase, Mutator family AAA_29 PF13555.1 KFY05091.1 - 0.005 16.3 3.1 0.023 14.1 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NTPase_1 PF03266.10 KFY05091.1 - 0.005 16.5 0.1 2.6 7.7 0.0 3.0 4 0 0 4 4 2 1 NTPase AAA_10 PF12846.2 KFY05091.1 - 0.0052 16.2 0.1 0.17 11.3 0.0 3.0 2 0 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 KFY05091.1 - 0.016 14.6 0.0 4.3 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KFY05091.1 - 0.023 13.6 0.0 4.7 6.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 KFY05091.1 - 0.024 14.2 0.1 6.9 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 KFY05091.1 - 0.029 13.4 0.0 0.076 12.0 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF258 PF03193.11 KFY05091.1 - 0.03 13.5 0.0 0.23 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Zot PF05707.7 KFY05091.1 - 0.032 13.7 1.4 1.4 8.3 0.0 3.2 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) Zeta_toxin PF06414.7 KFY05091.1 - 0.032 13.3 0.0 1.6 7.8 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin T2SE PF00437.15 KFY05091.1 - 0.036 12.9 0.0 1.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Miro PF08477.8 KFY05091.1 - 0.044 14.2 0.0 1 9.8 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_33 PF13671.1 KFY05091.1 - 0.049 13.4 0.1 6.5 6.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KFY05091.1 - 0.073 13.0 0.0 4 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KFY05091.1 - 0.14 11.8 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 KFY05091.1 - 0.16 11.4 0.1 0.47 9.9 0.0 1.8 2 0 0 2 2 1 0 Conserved hypothetical ATP binding protein UPF0079 PF02367.12 KFY05091.1 - 0.22 11.1 0.9 15 5.2 0.0 2.8 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 ArgK PF03308.11 KFY05091.1 - 0.38 9.4 0.0 7 5.3 0.0 2.6 3 0 0 3 3 3 0 ArgK protein DUF87 PF01935.12 KFY05091.1 - 0.48 10.1 5.1 2.4 7.9 0.1 2.8 1 1 1 2 2 2 0 Domain of unknown function DUF87 Methyltransf_23 PF13489.1 KFY05093.1 - 2.2e-21 76.2 0.0 3.4e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY05093.1 - 9.3e-13 48.4 0.0 1.6e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY05093.1 - 2.8e-10 39.9 0.0 3.5e-09 36.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY05093.1 - 2.3e-09 37.6 0.0 1.3e-08 35.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY05093.1 - 1.2e-08 35.4 0.0 1e-07 32.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY05093.1 - 1.5e-06 28.5 0.0 2.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFY05093.1 - 0.0019 17.3 0.0 0.017 14.2 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 KFY05093.1 - 0.0021 17.1 0.0 0.0097 14.9 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 KFY05093.1 - 0.0081 16.1 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 KFY05093.1 - 0.0092 15.3 0.0 0.21 10.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KFY05093.1 - 0.017 15.1 0.0 0.043 13.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KFY05093.1 - 0.019 14.0 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 KFY05093.1 - 0.11 11.5 0.0 0.31 10.0 0.0 1.7 2 1 0 2 2 2 0 Mycolic acid cyclopropane synthetase Glyco_hydro_7 PF00840.15 KFY05095.1 - 9.2e-134 446.0 9.7 4e-132 440.6 6.7 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_20 PF00686.14 KFY05097.1 - 1.4e-32 111.1 0.9 2.5e-32 110.3 0.6 1.4 1 0 0 1 1 1 1 Starch binding domain Chitin_bind_3 PF03067.10 KFY05097.1 - 1.7e-09 38.1 0.9 9.4e-07 29.2 0.1 2.6 2 1 0 2 2 2 1 Chitin binding domain PAD PF03068.10 KFY05100.1 - 1e-38 132.8 0.0 3.9e-34 117.7 0.0 3.0 2 1 0 2 2 2 2 Protein-arginine deiminase (PAD) Fungal_trans_2 PF11951.3 KFY05102.1 - 3.4e-29 101.6 4.6 4.1e-29 101.3 3.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY05102.1 - 4.6e-05 23.2 8.8 0.00011 22.0 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ras PF00071.17 KFY05103.1 - 1.3e-12 47.4 0.0 3.4e-12 46.0 0.0 1.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 KFY05103.1 - 0.00017 22.0 0.0 0.00033 21.1 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KFY05103.1 - 0.027 14.4 0.1 0.067 13.1 0.1 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase ArgK PF03308.11 KFY05103.1 - 0.036 12.8 0.5 5 5.8 0.1 2.1 2 0 0 2 2 2 0 ArgK protein AAA_17 PF13207.1 KFY05103.1 - 0.17 12.7 0.6 0.35 11.6 0.4 1.8 1 1 0 1 1 1 0 AAA domain AA_permease_2 PF13520.1 KFY05104.1 - 6.6e-77 258.8 27.3 1.2e-76 258.0 18.9 1.4 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFY05104.1 - 7.5e-15 54.2 25.7 7.5e-15 54.2 17.8 1.5 2 0 0 2 2 2 1 Amino acid permease Lipase_GDSL PF00657.17 KFY05105.1 - 2e-05 24.5 2.0 3.9e-05 23.6 1.4 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF778 PF05608.7 KFY05105.1 - 0.067 13.1 0.8 0.16 11.9 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF778) AA_permease_2 PF13520.1 KFY05106.1 - 1.9e-53 181.5 53.8 2.3e-53 181.2 37.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFY05106.1 - 1.3e-19 69.9 41.7 1.6e-19 69.6 28.9 1.1 1 0 0 1 1 1 1 Amino acid permease Cu_amine_oxid PF01179.15 KFY05107.1 - 7.6e-167 555.2 0.0 1e-166 554.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KFY05107.1 - 8.1e-21 73.9 0.0 1.7e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KFY05107.1 - 1.6e-13 50.5 0.1 3.7e-13 49.3 0.1 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain FSH1 PF03959.8 KFY05108.1 - 1.4e-25 90.0 0.0 5.3e-25 88.1 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) IucA_IucC PF04183.7 KFY05109.1 - 1.1e-21 77.1 0.2 1.6e-17 63.6 0.1 2.3 2 0 0 2 2 2 2 IucA / IucC family FhuF PF06276.7 KFY05109.1 - 2.4e-18 66.6 0.0 4.4e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter TauD PF02668.11 KFY05110.1 - 6.8e-31 107.8 0.0 9.2e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 KFY05110.1 - 0.0081 15.0 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 CsiD Peptidase_S8 PF00082.17 KFY05111.1 - 5.9e-52 176.5 9.8 8.4e-52 176.0 6.8 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KFY05111.1 - 1.8e-10 41.2 0.6 3.6e-10 40.2 0.4 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Uds1 PF15456.1 KFY05112.1 - 1.5e-41 141.2 2.3 1.5e-41 141.2 1.6 5.4 3 1 1 4 4 4 2 Up-regulated During Septation Reo_sigmaC PF04582.7 KFY05112.1 - 0.36 9.9 18.8 1.2 8.2 8.6 2.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 KFY05112.1 - 2.7 7.5 66.8 0.018 14.6 7.1 5.9 4 1 1 6 6 6 0 IncA protein Mnd1 PF03962.10 KFY05112.1 - 8.6 5.9 62.8 1.4 8.5 5.0 6.1 3 2 3 6 6 6 0 Mnd1 family Pex19 PF04614.7 KFY05114.1 - 1.1e-74 251.2 14.6 1.1e-74 251.2 10.1 1.9 1 1 1 2 2 2 1 Pex19 protein family DUF162 PF02589.10 KFY05114.1 - 0.00037 20.0 0.3 0.0007 19.1 0.2 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YkgG family COG1556 Vps4_C PF09336.5 KFY05114.1 - 0.024 14.4 0.2 0.097 12.5 0.0 2.1 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain FliE PF02049.13 KFY05114.1 - 0.029 14.3 2.6 0.029 14.3 1.8 3.4 2 2 1 4 4 4 0 Flagellar hook-basal body complex protein FliE FliG_N PF14842.1 KFY05114.1 - 0.27 11.3 3.8 0.19 11.8 0.4 2.5 3 0 0 3 3 3 0 FliG N-terminal domain DUF3782 PF12644.2 KFY05114.1 - 3.5 7.5 6.5 1.1e+02 2.6 4.4 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) Herpes_LMP2 PF07415.6 KFY05115.1 - 2.4 6.6 6.7 2.3 6.7 1.9 2.0 2 0 0 2 2 2 0 Gammaherpesvirus latent membrane protein (LMP2) protein Ribosomal_60s PF00428.14 KFY05116.1 - 3.5e-24 85.0 8.9 5e-24 84.5 6.2 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2408 PF10303.4 KFY05117.1 - 9.9e-48 161.6 0.3 1.9e-25 89.5 0.1 4.8 4 1 0 4 4 4 4 Protein of unknown function (DUF2408) DUF1664 PF07889.7 KFY05117.1 - 0.001 18.8 0.6 0.025 14.3 0.1 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) PolyG_pol PF01518.11 KFY05117.1 - 0.001 17.6 0.1 0.0018 16.8 0.1 1.2 1 0 0 1 1 1 1 Sigma NS protein Phage_term_smal PF05944.7 KFY05117.1 - 0.0045 16.6 0.0 0.03 13.9 0.0 2.2 2 0 0 2 2 2 1 Phage small terminase subunit COG6 PF06419.6 KFY05117.1 - 0.016 13.4 1.0 0.034 12.2 0.2 1.9 2 0 0 2 2 2 0 Conserved oligomeric complex COG6 Laminin_II PF06009.7 KFY05117.1 - 0.021 14.5 1.6 0.069 12.8 0.1 2.5 2 1 0 2 2 2 0 Laminin Domain II HR1 PF02185.11 KFY05117.1 - 0.1 12.3 1.2 0.24 11.1 0.1 2.3 2 0 0 2 2 2 0 Hr1 repeat Nop14 PF04147.7 KFY05117.1 - 0.38 8.6 2.7 1.2 6.9 0.1 1.6 1 1 1 2 2 2 0 Nop14-like family Cut8_C PF08559.5 KFY05118.1 - 4.5e-49 165.9 0.0 7.1e-49 165.3 0.0 1.3 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 KFY05118.1 - 9.8e-15 54.0 1.8 1.2e-14 53.7 0.3 2.0 2 0 0 2 2 2 1 Cut8 dimerisation domain Cut8_N PF14482.1 KFY05118.1 - 5.9e-09 35.7 1.7 5.9e-09 35.7 1.2 1.9 2 0 0 2 2 2 1 Cut8 proteasome-binding domain SUV3_C PF12513.3 KFY05120.1 - 0.042 13.2 0.0 0.38 10.2 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal DUF3435 PF11917.3 KFY05124.1 - 3.3e-46 157.8 0.1 4.1e-46 157.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Glutaredoxin PF00462.19 KFY05126.1 - 2.4e-18 65.8 0.0 3.8e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin CYSTM PF12734.2 KFY05127.1 - 5.9e-12 45.4 16.2 5.9e-12 45.4 11.2 5.0 3 1 0 3 3 3 1 Cysteine-rich TM module stress tolerance Pro-rich PF15240.1 KFY05127.1 - 5.7 6.9 36.3 6.8 6.7 25.2 1.1 1 0 0 1 1 1 0 Proline-rich A_deaminase PF00962.17 KFY05128.1 - 1.5e-111 372.4 0.2 2e-111 372.1 0.1 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase UAA PF08449.6 KFY05129.1 - 1.4e-92 309.8 6.2 1.8e-92 309.5 4.3 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 KFY05129.1 - 9.2e-05 21.6 5.1 0.00029 20.0 3.5 1.9 1 1 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 KFY05129.1 - 0.00042 20.4 14.9 0.011 15.9 2.1 3.3 2 1 1 3 3 3 2 Multidrug resistance efflux transporter Pox_A14 PF05767.7 KFY05129.1 - 0.13 12.2 0.0 0.13 12.2 0.0 2.2 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 TPT PF03151.11 KFY05129.1 - 0.16 11.6 17.6 0.025 14.2 6.1 2.9 2 1 0 2 2 2 0 Triose-phosphate Transporter family LSM PF01423.17 KFY05131.1 - 7.6e-16 57.4 1.0 1e-15 56.9 0.7 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KFY05131.1 - 0.025 14.5 0.1 0.032 14.1 0.1 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain Gemin7 PF11095.3 KFY05131.1 - 0.037 13.7 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Muskelin_N PF06588.6 KFY05131.1 - 0.11 12.1 0.1 0.13 11.9 0.1 1.3 1 1 0 1 1 1 0 Muskelin N-terminus MFS_1 PF07690.11 KFY05134.1 - 8.2e-36 123.4 68.9 4.4e-32 111.1 37.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Epimerase PF01370.16 KFY05134.1 - 5.2e-12 45.7 0.0 1.6e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFY05134.1 - 3.1e-09 35.9 0.0 5.3e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KFY05134.1 - 2e-08 34.4 0.5 4.1e-08 33.4 0.3 1.6 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KFY05134.1 - 0.00015 20.8 0.3 0.00049 19.0 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.8 KFY05134.1 - 0.016 14.4 0.3 0.03 13.5 0.2 1.5 1 0 0 1 1 1 0 NmrA-like family Abhydrolase_6 PF12697.2 KFY05135.1 - 7.4e-28 97.9 0.0 1.3e-27 97.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KFY05135.1 - 8.1e-09 35.3 0.1 1.6e-08 34.3 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KFY05135.1 - 6.3e-07 29.2 0.0 2.9e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KFY05135.1 - 0.0098 15.3 0.0 1.2 8.4 0.0 2.7 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase FAD_binding_3 PF01494.14 KFY05136.1 - 5.6e-14 51.9 0.0 5.3e-13 48.7 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KFY05136.1 - 0.0013 18.7 0.0 0.0038 17.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFY05136.1 - 0.016 14.1 0.1 0.74 8.6 0.1 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF1460 PF07313.7 KFY05136.1 - 0.16 11.1 0.5 0.3 10.2 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1460) Lycopene_cycl PF05834.7 KFY05136.1 - 0.16 10.8 0.5 4 6.2 0.0 2.7 2 1 0 2 2 2 0 Lycopene cyclase protein Ank_2 PF12796.2 KFY05137.1 - 8.8e-59 195.8 0.1 2e-21 76.1 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KFY05137.1 - 2.1e-57 188.1 0.0 9.7e-09 34.6 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 KFY05137.1 - 1.7e-47 158.9 2.8 5.3e-10 39.5 0.0 6.3 1 1 6 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY05137.1 - 4.3e-41 134.8 0.0 1.3e-05 24.9 0.0 7.4 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.1 KFY05137.1 - 2.7e-31 106.8 0.0 2.1e-06 27.7 0.0 5.6 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Cullin PF00888.17 KFY05139.1 - 4.3e-202 672.8 12.1 5.3e-202 672.4 8.4 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KFY05139.1 - 5.7e-25 86.9 5.2 5.7e-25 86.9 3.6 2.8 2 0 0 2 2 2 1 Cullin protein neddylation domain TatD_DNase PF01026.16 KFY05140.1 - 4e-32 111.4 0.0 7.2e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 TatD related DNase RGP PF03214.8 KFY05140.1 - 0.019 13.7 0.0 0.52 9.0 0.0 2.1 1 1 0 2 2 2 0 Reversibly glycosylated polypeptide ResIII PF04851.10 KFY05141.1 - 1.4e-21 77.2 0.0 3e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KFY05141.1 - 6.1e-14 51.6 0.0 1.5e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KFY05141.1 - 3.1e-10 39.8 0.0 9.1e-10 38.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 KFY05141.1 - 0.019 13.9 0.0 0.036 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF2034 PF10356.4 KFY05142.1 - 4.9e-32 110.5 0.0 1.2e-15 57.1 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 KFY05142.1 - 3.8e-09 36.3 0.0 5.6e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease DUF4365 PF14280.1 KFY05142.1 - 0.007 16.0 0.0 0.017 14.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4365) TMEM141 PF15110.1 KFY05142.1 - 0.071 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 TMEM141 protein family Med21 PF11221.3 KFY05143.1 - 7.7e-44 149.1 2.9 9.1e-44 148.9 2.0 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex GAS PF13851.1 KFY05143.1 - 0.0027 16.9 5.7 0.12 11.5 3.2 2.0 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding Med9 PF07544.8 KFY05143.1 - 0.0096 15.6 4.3 0.0096 15.6 3.0 2.3 2 1 1 3 3 3 1 RNA polymerase II transcription mediator complex subunit 9 Orbi_VP5 PF00901.12 KFY05143.1 - 0.051 11.7 2.4 0.059 11.5 1.7 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 HA PF03457.9 KFY05143.1 - 0.061 13.4 0.0 0.23 11.5 0.0 2.0 1 1 0 1 1 1 0 Helicase associated domain Herpes_UL6 PF01763.11 KFY05143.1 - 0.071 11.2 0.2 0.078 11.1 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like FYVE_2 PF02318.11 KFY05143.1 - 0.2 11.5 2.2 0.31 10.9 1.5 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger AAA_23 PF13476.1 KFY05143.1 - 0.23 11.7 4.0 0.29 11.4 2.8 1.1 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 KFY05143.1 - 0.31 10.0 5.6 0.45 9.5 3.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 CART PF06373.6 KFY05143.1 - 0.55 10.2 1.9 1.1 9.3 1.3 1.6 1 0 0 1 1 1 0 Cocaine and amphetamine regulated transcript protein (CART) Mnd1 PF03962.10 KFY05143.1 - 1.3 8.6 6.4 0.74 9.4 3.4 1.4 2 0 0 2 2 2 0 Mnd1 family DUF4140 PF13600.1 KFY05143.1 - 2.9 8.3 7.1 0.86 10.0 2.7 1.8 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Pkinase PF00069.20 KFY05146.1 - 8.8e-72 241.3 0.0 1.1e-71 241.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY05146.1 - 2.5e-31 108.7 0.0 3.3e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KFY05146.1 - 3.7e-05 22.8 0.0 0.00013 21.1 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KFY05146.1 - 0.0005 19.8 0.0 0.00099 18.9 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KFY05146.1 - 0.00055 18.9 0.0 0.027 13.4 0.0 2.3 1 1 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KFY05146.1 - 0.025 13.9 0.0 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 RIO1 family WD40 PF00400.27 KFY05148.1 - 7.2e-54 177.8 16.5 1.4e-09 37.4 0.0 12.1 13 0 0 13 13 13 8 WD domain, G-beta repeat WHIM1 PF15612.1 KFY05148.1 - 0.0017 18.2 0.0 0.0051 16.6 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Daxx PF03344.10 KFY05148.1 - 0.35 9.2 11.7 0.69 8.3 8.1 1.4 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 KFY05148.1 - 0.58 8.0 11.0 0.88 7.4 7.6 1.2 1 0 0 1 1 1 0 Nop14-like family MSP1_C PF07462.6 KFY05148.1 - 8.1 4.6 5.4 15 3.7 3.7 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus ABC_tran PF00005.22 KFY05149.1 - 9.1e-17 61.6 0.0 2.7e-16 60.1 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KFY05149.1 - 1.2e-09 38.5 0.4 0.0013 18.8 0.1 2.1 1 1 1 2 2 2 2 AAA domain AAA_15 PF13175.1 KFY05149.1 - 1.5e-05 24.2 0.0 0.096 11.7 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 KFY05149.1 - 0.00011 21.5 0.0 0.4 9.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFY05149.1 - 0.00023 20.5 0.4 0.00053 19.4 0.1 1.6 2 0 0 2 2 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KFY05149.1 - 0.0028 17.0 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KFY05149.1 - 0.0034 17.7 0.1 0.0066 16.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KFY05149.1 - 0.0052 16.7 0.2 0.0071 16.3 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain DUF3584 PF12128.3 KFY05149.1 - 0.0064 13.9 0.3 0.0083 13.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) PduV-EutP PF10662.4 KFY05149.1 - 0.0065 15.9 0.1 0.01 15.3 0.1 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 KFY05149.1 - 0.013 14.9 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_17 PF13207.1 KFY05149.1 - 0.018 15.8 0.9 0.037 14.8 0.6 1.7 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 KFY05149.1 - 0.068 13.6 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Miro-like protein AAA_10 PF12846.2 KFY05149.1 - 0.077 12.4 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain NACHT PF05729.7 KFY05149.1 - 0.086 12.4 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.1 KFY05149.1 - 0.099 12.5 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.1 KFY05149.1 - 0.11 10.9 0.0 0.15 10.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 KFY05149.1 - 0.12 12.1 0.8 0.69 9.6 0.1 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KFY05149.1 - 0.14 12.3 0.9 0.49 10.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KFY05149.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF1770 PF08589.5 KFY05150.1 - 2e-25 89.2 1.3 3.1e-25 88.6 0.9 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) DER1 PF04511.10 KFY05151.1 - 3.2e-25 88.8 4.3 3.7e-25 88.5 3.0 1.0 1 0 0 1 1 1 1 Der1-like family DUF3384 PF11864.3 KFY05152.1 - 6.4e-92 308.4 0.0 1.1e-91 307.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 KFY05152.1 - 2e-55 187.0 0.0 3.4e-55 186.3 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 KFY05152.1 - 2.1e-35 122.4 1.0 5.8e-32 111.1 0.0 2.4 2 0 0 2 2 2 2 Tuberin Cse1 PF08506.5 KFY05153.1 - 1.2e-153 511.0 0.6 1.8e-153 510.4 0.4 1.3 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.10 KFY05153.1 - 1.7e-98 329.7 1.7 6.6e-98 327.8 0.1 2.4 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 KFY05153.1 - 4.9e-12 45.6 0.0 1.7e-11 43.8 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KFY05153.1 - 0.014 15.2 8.5 0.31 10.9 0.0 5.6 7 0 0 7 7 7 0 Exportin 1-like protein HEAT_2 PF13646.1 KFY05153.1 - 0.1 12.8 0.1 2.2 8.6 0.0 3.0 3 0 0 3 3 3 0 HEAT repeats Methyltransf_23 PF13489.1 KFY05157.1 - 1.3e-19 70.4 0.1 1e-18 67.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY05157.1 - 2.5e-06 28.0 0.0 3.2e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY05157.1 - 5.4e-06 26.0 0.0 0.00011 21.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY05157.1 - 0.00059 20.2 0.0 0.0074 16.7 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KFY05157.1 - 0.00091 19.6 0.0 0.0021 18.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY05157.1 - 0.0064 16.8 0.0 0.02 15.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KFY05157.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 KFY05157.1 - 0.018 15.0 0.0 0.074 13.0 0.0 1.9 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 KFY05157.1 - 0.058 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 KFY05157.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ank_2 PF12796.2 KFY05158.1 - 1.8e-27 95.4 3.6 4e-11 43.1 0.1 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KFY05158.1 - 1.4e-22 79.6 10.1 1.4e-07 31.8 0.2 7.3 3 2 5 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.25 KFY05158.1 - 1e-19 69.2 13.1 2.3e-06 27.1 0.0 8.2 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 KFY05158.1 - 3e-19 68.6 5.3 2.1e-08 34.1 0.1 5.1 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY05158.1 - 4.2e-18 63.6 6.7 0.0034 17.4 0.0 8.2 8 1 0 8 8 8 4 Ankyrin repeat DUF1828 PF08861.5 KFY05158.1 - 0.039 13.5 0.1 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF1828 CFEM PF05730.6 KFY05161.1 - 1e-08 34.8 10.3 1.7e-08 34.1 7.1 1.4 1 0 0 1 1 1 1 CFEM domain SET PF00856.23 KFY05165.1 - 1e-15 58.4 0.3 2e-14 54.2 0.1 2.7 2 1 0 2 2 2 1 SET domain Ribonucleas_3_3 PF14622.1 KFY05166.1 - 1.2e-11 44.6 0.0 1.7e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KFY05166.1 - 5.3e-11 42.9 0.0 1.9e-10 41.1 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Peptidase_C65 PF10275.4 KFY05169.1 - 8.3e-66 221.8 0.0 1e-65 221.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain TauD PF02668.11 KFY05172.1 - 5.8e-13 49.1 0.0 6.9e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AAA_17 PF13207.1 KFY05173.1 - 2.3e-07 31.6 0.4 6.3e-07 30.2 0.3 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFY05173.1 - 1.4e-05 24.9 0.0 2.9e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KFY05173.1 - 0.00017 21.8 0.0 0.00027 21.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 KFY05173.1 - 0.00041 20.2 0.0 0.0022 17.8 0.0 2.1 1 1 0 1 1 1 1 Shikimate kinase Zeta_toxin PF06414.7 KFY05173.1 - 0.011 14.8 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 KFY05173.1 - 0.087 13.1 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Aminotran_1_2 PF00155.16 KFY05174.1 - 7.7e-88 294.8 0.0 8.9e-88 294.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II AAA_17 PF13207.1 KFY05175.1 - 2.7e-06 28.1 0.0 6.3e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 KFY05175.1 - 2.7e-05 23.8 0.0 5e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.1 KFY05175.1 - 0.00013 22.3 0.0 0.00097 19.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 KFY05175.1 - 0.023 14.2 0.0 0.053 13.0 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 KFY05175.1 - 0.039 13.9 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KFY05175.1 - 0.057 12.5 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin G-alpha PF00503.15 KFY05175.1 - 0.093 11.4 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit CoaE PF01121.15 KFY05175.1 - 0.099 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_16 PF13191.1 KFY05175.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Cu_amine_oxid PF01179.15 KFY05178.1 - 5.9e-140 466.6 0.0 4.7e-104 348.3 0.0 2.1 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KFY05178.1 - 1.5e-19 69.9 0.0 3.8e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KFY05178.1 - 7.1e-16 58.0 0.1 1.6e-15 56.8 0.1 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain CAF-1_p150 PF11600.3 KFY05179.1 - 0.023 14.1 6.3 0.026 13.9 4.4 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Presenilin PF01080.12 KFY05179.1 - 0.68 8.6 3.0 0.8 8.4 2.1 1.0 1 0 0 1 1 1 0 Presenilin PD40 PF07676.7 KFY05180.1 - 0.0025 17.4 0.2 0.17 11.5 0.0 2.6 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 KFY05180.1 - 0.031 13.6 0.0 0.066 12.6 0.0 1.6 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain Cyclin_N PF00134.18 KFY05181.1 - 2e-12 46.7 0.0 3.2e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KFY05181.1 - 6.1e-08 33.1 0.0 8.4e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin Gag_p24 PF00607.15 KFY05182.1 - 0.0057 16.2 5.4 0.0071 15.9 3.8 1.1 1 0 0 1 1 1 1 gag gene protein p24 (core nucleocapsid protein) OspD PF03207.8 KFY05182.1 - 0.0064 15.6 1.0 0.0084 15.2 0.7 1.1 1 0 0 1 1 1 1 Borrelia outer surface protein D (OspD) DUF2317 PF10079.4 KFY05182.1 - 0.33 9.5 6.5 0.4 9.2 4.5 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Spc7 PF08317.6 KFY05184.1 - 0.037 12.7 3.3 0.046 12.3 2.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FH2 PF02181.18 KFY05184.1 - 0.073 11.9 1.3 0.086 11.7 0.9 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain DUF3552 PF12072.3 KFY05184.1 - 0.11 11.7 5.7 0.14 11.3 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) FlhC PF05280.6 KFY05184.1 - 0.13 11.7 0.3 0.26 10.7 0.1 1.6 1 1 0 1 1 1 0 Flagellar transcriptional activator (FlhC) IncA PF04156.9 KFY05184.1 - 0.19 11.3 5.4 0.27 10.7 3.8 1.3 1 0 0 1 1 1 0 IncA protein Pox_A_type_inc PF04508.7 KFY05184.1 - 0.19 11.5 7.7 0.52 10.2 0.3 3.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat HSBP1 PF06825.7 KFY05184.1 - 0.35 10.4 2.8 0.35 10.4 0.8 1.8 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Sugarporin_N PF11471.3 KFY05184.1 - 0.59 9.8 3.4 7.9 6.2 1.1 3.1 2 1 1 3 3 3 0 Maltoporin periplasmic N-terminal extension DDE_1 PF03184.14 KFY05186.1 - 8.6e-07 28.3 0.0 1.4e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Ank_4 PF13637.1 KFY05187.1 - 1.8e-35 120.6 2.9 2.3e-08 34.3 0.0 6.2 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 KFY05187.1 - 2e-34 115.6 13.9 3.3e-05 23.4 0.0 7.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_2 PF12796.2 KFY05187.1 - 6.1e-32 109.8 0.0 7.4e-09 35.8 0.0 4.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KFY05187.1 - 9.3e-31 105.1 29.2 6.3e-08 32.6 0.3 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY05187.1 - 3.3e-26 88.7 0.0 0.004 17.2 0.0 7.6 7 0 0 7 7 7 5 Ankyrin repeat NIL PF09383.5 KFY05187.1 - 1.1e-09 37.7 0.1 12 5.6 0.0 7.0 7 0 0 7 7 7 0 NIL domain NACHT PF05729.7 KFY05187.1 - 2.3e-07 30.6 0.1 5.7e-07 29.3 0.1 1.6 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.9 KFY05187.1 - 3.6e-05 23.1 0.0 6.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_16 PF13191.1 KFY05187.1 - 0.00013 21.9 0.1 0.00034 20.6 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain Abhydrolase_5 PF12695.2 KFY05187.1 - 0.00056 19.6 0.0 0.0014 18.3 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KFY05187.1 - 0.0016 18.3 0.0 0.0031 17.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_22 PF13401.1 KFY05187.1 - 0.0077 16.3 0.0 0.028 14.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain PGAP1 PF07819.8 KFY05187.1 - 0.0099 15.4 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Nitro_FeMo-Co PF02579.12 KFY05187.1 - 0.075 13.1 2.2 51 4.0 0.0 4.3 2 1 1 4 4 4 0 Dinitrogenase iron-molybdenum cofactor RNA_helicase PF00910.17 KFY05187.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase RabGAP-TBC PF00566.13 KFY05188.1 - 6.1e-46 156.5 0.0 1e-45 155.8 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.1 KFY05188.1 - 1.7e-05 24.8 0.1 0.0011 19.0 0.2 3.5 3 0 0 3 3 3 1 EF-hand domain pair GRAM PF02893.15 KFY05188.1 - 0.00027 20.3 0.0 0.0007 19.0 0.0 1.8 1 1 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.1 KFY05188.1 - 0.00035 20.2 3.0 0.0095 15.7 0.2 3.9 5 0 0 5 5 5 1 EF-hand domain EF-hand_1 PF00036.27 KFY05188.1 - 0.0032 16.6 0.4 0.097 12.0 0.3 3.2 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.1 KFY05188.1 - 0.025 13.9 2.9 0.057 12.7 0.6 2.7 3 0 0 3 3 3 0 EF hand DUF3441 PF11923.3 KFY05189.1 - 1.6e-35 121.0 0.2 1.6e-35 121.0 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) FbpA PF05833.6 KFY05189.1 - 1.8e-30 105.8 5.0 1.8e-30 105.8 3.5 3.8 3 1 0 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 KFY05189.1 - 3.2e-21 74.9 0.0 7.3e-21 73.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) zf-C3H1 PF10650.4 KFY05189.1 - 2.8e-13 49.0 1.3 4.5e-13 48.3 0.9 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain Myosin_head PF00063.16 KFY05190.1 - 9.8e-252 836.9 0.1 9.8e-252 836.9 0.0 2.4 3 0 0 3 3 3 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 KFY05190.1 - 2.9e-28 98.1 262.9 1.6e-25 89.0 73.0 6.8 2 2 2 5 5 5 4 Myosin tail Myosin_N PF02736.14 KFY05190.1 - 2.6e-06 26.9 0.0 6.1e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Filament PF00038.16 KFY05190.1 - 0.0017 17.9 8.2 0.0017 17.9 5.7 9.9 1 1 7 9 9 9 4 Intermediate filament protein AAA_19 PF13245.1 KFY05190.1 - 0.08 12.6 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain CTP_synth_N PF06418.9 KFY05191.1 - 3.3e-111 370.8 0.1 5e-111 370.2 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KFY05191.1 - 5.7e-53 179.2 0.0 8.5e-53 178.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KFY05191.1 - 1.1e-06 28.2 0.0 4.9e-06 26.1 0.0 2.1 1 1 1 2 2 2 1 Peptidase C26 CbiA PF01656.18 KFY05191.1 - 0.0024 17.3 0.0 0.0052 16.2 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain F-box PF00646.28 KFY05192.1 - 0.00031 20.2 0.6 0.0016 18.0 0.1 2.3 2 0 0 2 2 2 1 F-box domain TauD PF02668.11 KFY05195.1 - 1.5e-32 113.3 0.5 1.6e-32 113.1 0.3 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AAA_10 PF12846.2 KFY05197.1 - 2.8e-09 36.8 0.0 0.00012 21.5 0.0 2.3 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 KFY05197.1 - 0.00015 21.3 0.2 0.0015 18.0 0.0 2.3 2 1 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 KFY05197.1 - 0.00079 19.5 0.0 1.6 8.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 KFY05197.1 - 0.013 15.0 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 KFY05197.1 - 0.044 12.8 0.0 0.094 11.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF87 PF01935.12 KFY05197.1 - 0.059 13.1 0.0 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 TrwB_AAD_bind PF10412.4 KFY05197.1 - 0.064 11.8 0.4 0.75 8.3 0.0 2.5 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain DUF3437 PF11919.3 KFY05197.1 - 0.067 12.9 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) AAA_34 PF13872.1 KFY05197.1 - 0.081 11.6 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 MFS_1 PF07690.11 KFY05198.1 - 1.5e-18 66.6 64.1 5.8e-16 58.1 24.8 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily YesK PF14150.1 KFY05198.1 - 0.036 14.1 1.4 0.036 14.1 1.0 3.7 4 0 0 4 4 4 0 YesK-like protein Sugar_tr PF00083.19 KFY05200.1 - 2.3e-82 277.0 18.4 5.3e-82 275.7 12.7 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY05200.1 - 4.5e-30 104.5 10.1 7.7e-30 103.7 7.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KFY05200.1 - 9.8e-06 24.2 10.2 1.2e-05 23.9 1.4 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein Tmemb_170 PF10190.4 KFY05200.1 - 0.007 16.4 0.3 0.007 16.4 0.2 2.6 2 1 1 3 3 3 1 Putative transmembrane protein 170 Fungal_trans_2 PF11951.3 KFY05201.1 - 0.00058 18.5 0.2 0.0015 17.2 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain TMEM107 PF14995.1 KFY05201.1 - 0.69 10.0 4.5 3.7 7.6 0.7 2.3 2 0 0 2 2 2 0 Transmembrane protein Oxidored_FMN PF00724.15 KFY05202.1 - 5.8e-77 258.9 0.0 7e-77 258.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.11 KFY05204.1 - 3e-31 108.4 67.4 5.2e-29 101.0 37.1 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY05204.1 - 1.2e-12 47.2 10.1 1.2e-12 47.2 7.0 3.4 2 1 0 3 3 3 1 Sugar (and other) transporter Anp1 PF03452.9 KFY05206.1 - 5.1e-103 343.9 0.0 6.2e-103 343.6 0.0 1.1 1 0 0 1 1 1 1 Anp1 HhH-GPD PF00730.20 KFY05207.1 - 7.5e-16 58.3 0.0 1.5e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF2668 PF10873.3 KFY05207.1 - 0.44 10.6 3.4 4.9 7.3 2.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) TFIIF_alpha PF05793.7 KFY05207.1 - 5.7 5.1 5.7 8.1 4.6 3.9 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) tRNA-synt_1 PF00133.17 KFY05209.1 - 2.3e-58 197.6 0.0 1.6e-21 76.0 0.1 6.1 1 1 4 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 KFY05209.1 - 9.1e-42 142.4 0.0 1.5e-41 141.7 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 KFY05209.1 - 2.6e-28 98.7 0.0 1.7e-20 73.0 0.0 4.1 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KFY05209.1 - 2.4e-08 33.8 0.1 4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KFY05209.1 - 0.0073 15.4 0.0 0.25 10.4 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 KFY05209.1 - 0.0087 14.9 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (R) MIF4G PF02854.14 KFY05209.1 - 0.17 11.2 0.1 0.63 9.4 0.0 1.8 2 0 0 2 2 2 0 MIF4G domain AA_permease_2 PF13520.1 KFY05210.1 - 5.8e-64 216.1 35.9 7.9e-64 215.7 24.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KFY05210.1 - 3.5e-29 101.4 27.2 3.5e-29 101.4 18.9 2.0 2 0 0 2 2 2 2 Amino acid permease Glyco_hydro_43 PF04616.9 KFY05213.1 - 3.5e-17 62.4 2.3 5.5e-17 61.7 1.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_61 PF03443.9 KFY05214.1 - 4.6e-46 157.3 0.1 8e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KFY05214.1 - 9.4e-13 47.5 12.4 3.1e-12 45.9 8.6 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KFY05214.1 - 0.3 11.1 3.1 0.59 10.2 2.2 1.5 1 0 0 1 1 1 0 Toxin 7 Glyco_hydro_61 PF03443.9 KFY05215.1 - 2.2e-66 223.7 0.1 3.7e-66 223.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KFY05215.1 - 3.1e-12 45.9 12.6 8.1e-12 44.5 8.7 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain HTH_Tnp_ISL3 PF13542.1 KFY05215.1 - 0.14 11.3 0.1 0.31 10.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Amino_oxidase PF01593.19 KFY05216.1 - 4.2e-36 124.9 0.0 3.2e-35 122.1 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KFY05216.1 - 1.8e-11 43.9 0.0 5.9e-11 42.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KFY05216.1 - 2.3e-05 24.5 0.1 0.00019 21.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFY05216.1 - 0.00021 19.9 0.1 0.00034 19.2 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 KFY05216.1 - 0.0012 17.9 0.3 0.0019 17.3 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KFY05216.1 - 0.008 16.0 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KFY05216.1 - 0.011 15.3 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 KFY05216.1 - 0.012 15.9 0.1 0.032 14.6 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KFY05216.1 - 0.031 13.1 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 KFY05216.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A GMC_oxred_C PF05199.8 KFY05217.1 - 5.1e-31 107.9 0.0 9.3e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KFY05217.1 - 2.7e-30 105.5 0.0 7.4e-25 87.7 0.0 2.8 1 1 1 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.1 KFY05217.1 - 0.00022 21.1 1.9 0.00083 19.3 1.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KFY05217.1 - 0.0013 17.7 0.0 0.0018 17.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KFY05217.1 - 0.006 15.5 0.8 0.15 10.9 0.6 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KFY05217.1 - 0.013 15.3 0.1 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KFY05217.1 - 0.024 14.0 0.4 0.045 13.2 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 KFY05217.1 - 0.028 13.3 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KFY05217.1 - 0.057 13.4 0.0 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KFY05217.1 - 0.091 11.2 0.3 0.13 10.7 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 KFY05217.1 - 0.16 11.6 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GAS2 PF02187.12 KFY05220.1 - 0.0001 21.9 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CFEM PF05730.6 KFY05222.1 - 3e-33 113.4 36.1 1.2e-11 44.2 6.0 3.5 3 0 0 3 3 3 3 CFEM domain Ribosomal_L40e PF01020.12 KFY05222.1 - 0.7 9.5 8.8 7.7 6.1 0.2 3.7 3 0 0 3 3 3 0 Ribosomal L40e family RepA1_leader PF08048.7 KFY05222.1 - 0.81 9.7 6.5 63 3.7 0.2 3.7 3 0 0 3 3 3 0 Tap RepA1 leader peptide Sugar_tr PF00083.19 KFY05223.1 - 1.2e-104 350.4 25.6 1.4e-104 350.2 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KFY05223.1 - 2.5e-19 69.1 41.7 6.4e-13 48.1 6.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Methyltransf_2 PF00891.13 KFY05224.1 - 1.1e-26 93.4 0.0 2.7e-26 92.2 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Acyl-CoA_dh_1 PF00441.19 KFY05224.1 - 1.5e-22 80.3 0.4 2.9e-22 79.3 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KFY05224.1 - 2.3e-11 44.2 0.1 1.1e-10 42.0 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KFY05224.1 - 1.6e-08 33.9 0.1 3.7e-08 32.7 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KFY05224.1 - 1.3e-05 25.4 0.8 3e-05 24.2 0.6 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF1705 PF08019.7 KFY05225.1 - 0.86 9.0 13.6 0.11 12.0 1.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1705) p450 PF00067.17 KFY05226.1 - 2.1e-55 188.0 0.0 3.3e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Oxidored_molyb PF00174.14 KFY05226.1 - 4.8e-47 159.4 0.0 8.1e-47 158.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KFY05226.1 - 1.8e-36 124.6 0.3 4e-36 123.5 0.2 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.16 KFY05226.1 - 7.7e-25 87.5 0.0 2.7e-24 85.8 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KFY05226.1 - 1e-21 76.9 0.0 4.9e-21 74.7 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 KFY05226.1 - 1.3e-14 53.7 0.4 5.4e-14 51.7 0.1 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 KFY05226.1 - 0.046 13.6 0.0 1.8 8.4 0.0 2.7 1 1 0 2 2 2 0 Ferric reductase NAD binding domain Alpha-L-AF_C PF06964.7 KFY05227.1 - 6.4e-33 114.0 0.1 9.1e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Glyco_hydr_30_2 PF14587.1 KFY05228.1 - 6.2e-17 61.5 5.9 1.2e-16 60.6 4.1 1.4 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Alpha-L-AF_C PF06964.7 KFY05228.1 - 0.00064 19.5 0.1 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus NmrA PF05368.8 KFY05229.1 - 1e-33 116.5 0.0 5.7e-33 114.1 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KFY05229.1 - 3.8e-11 43.3 0.0 5.1e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KFY05229.1 - 0.00047 19.6 0.0 0.0015 17.9 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KFY05229.1 - 0.00048 18.9 0.0 0.00072 18.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KFY05229.1 - 0.022 14.7 0.0 0.035 14.1 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.20 KFY05229.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase MFS_1 PF07690.11 KFY05230.1 - 2.7e-35 121.7 50.5 4.8e-35 120.8 35.0 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1427 PF07235.6 KFY05230.1 - 0.053 13.6 0.1 0.17 11.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1427) But2 PF09792.4 KFY05231.1 - 3.1e-19 69.1 0.5 7.1e-19 67.9 0.1 1.8 2 1 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain SPX PF03105.14 KFY05232.1 - 0.17 11.6 3.1 0.2 11.4 2.2 1.1 1 0 0 1 1 1 0 SPX domain DUF4192 PF13830.1 KFY05232.1 - 0.31 10.6 3.5 0.37 10.3 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) Ank_2 PF12796.2 KFY05234.1 - 1.1e-26 92.9 0.1 4.3e-12 46.2 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KFY05234.1 - 7.1e-21 72.2 0.0 0.00088 19.2 0.0 6.1 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.25 KFY05234.1 - 4.7e-20 70.3 0.0 0.0016 18.1 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 KFY05234.1 - 2.6e-19 69.1 0.0 7.2e-08 32.7 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY05234.1 - 8.4e-14 51.2 0.1 3e-05 24.0 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) AAA_22 PF13401.1 KFY05234.1 - 1.4e-08 34.9 0.5 5e-08 33.1 0.1 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KFY05234.1 - 2.1e-08 34.0 0.0 1.8e-07 30.9 0.0 2.5 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.1 KFY05234.1 - 9.4e-06 25.7 0.1 4e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain KaiC PF06745.8 KFY05234.1 - 1.6e-05 24.1 0.0 4e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 KaiC AAA_17 PF13207.1 KFY05234.1 - 0.042 14.6 0.1 1.8 9.4 0.0 3.0 2 0 0 2 2 2 0 AAA domain ATG16 PF08614.6 KFY05235.1 - 0.099 12.4 37.6 0.016 15.0 11.5 3.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3584 PF12128.3 KFY05235.1 - 0.74 7.0 30.8 1.1 6.4 21.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF812 PF05667.6 KFY05235.1 - 1.5 7.2 33.2 0.13 10.7 6.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF4472 PF14739.1 KFY05236.1 - 0.0017 18.7 1.7 0.0064 16.9 1.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4472) DUF4238 PF14022.1 KFY05236.1 - 0.21 10.8 1.0 0.95 8.6 0.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4238) 5_3_exonuc PF01367.15 KFY05236.1 - 0.48 10.6 2.2 0.75 10.0 0.3 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold DMPK_coil PF08826.5 KFY05236.1 - 3.3 7.6 9.3 4.8 7.1 1.3 2.9 1 1 2 3 3 3 0 DMPK coiled coil domain like DUF1956 PF09209.6 KFY05237.1 - 0.034 14.0 0.0 9 6.2 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1956) DUF1556 PF07590.6 KFY05237.1 - 0.62 10.3 13.8 33 4.7 0.0 4.6 1 1 5 6 6 6 0 Protein of unknown function (DUF1556) AAA PF00004.24 KFY05238.1 - 9.6e-18 64.6 0.0 2.3e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KFY05238.1 - 3.4e-05 23.9 0.2 0.00037 20.6 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 KFY05238.1 - 0.00014 21.6 0.1 0.00055 19.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 KFY05238.1 - 0.00024 20.7 0.1 0.0008 19.0 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KFY05238.1 - 0.00056 19.9 0.0 0.0027 17.6 0.0 2.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 KFY05238.1 - 0.00098 19.9 0.4 0.0042 17.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KFY05238.1 - 0.003 17.8 0.2 0.017 15.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KFY05238.1 - 0.0031 17.5 0.0 0.79 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KFY05238.1 - 0.012 14.6 0.0 0.024 13.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KFY05238.1 - 0.015 15.1 0.0 0.045 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KFY05238.1 - 0.032 14.1 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KFY05238.1 - 0.034 13.3 0.1 0.074 12.2 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 KFY05238.1 - 0.084 13.0 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 KFY05238.1 - 0.098 12.3 0.1 0.72 9.4 0.0 2.3 1 1 1 2 2 2 0 NACHT domain Zot PF05707.7 KFY05238.1 - 0.1 12.0 0.1 2.7 7.4 0.0 2.6 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) AAA_11 PF13086.1 KFY05238.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KFY05238.1 - 0.13 11.6 0.1 0.35 10.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain HEAT_2 PF13646.1 KFY05239.1 - 0.051 13.8 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 HEAT repeats Pkinase_Tyr PF07714.12 KFY05241.1 - 8e-12 44.7 0.0 3.3e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 KFY05241.1 - 1.8e-09 37.1 0.0 3.2e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KFY05241.1 - 6.8e-09 35.8 0.4 0.0018 18.0 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 KFY05241.1 - 3.4e-06 26.8 0.0 0.0063 16.1 0.0 2.1 1 1 1 2 2 2 2 Choline/ethanolamine kinase DZR PF12773.2 KFY05242.1 - 2 8.3 6.2 3.1 7.7 2.6 2.1 1 1 1 2 2 2 0 Double zinc ribbon DUF718 PF05336.8 KFY05245.1 - 1.5e-33 114.8 0.1 2e-33 114.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF718) HpaP PF09483.5 KFY05245.1 - 0.099 12.5 4.9 0.14 12.1 3.4 1.2 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Thioredoxin PF00085.15 KFY05246.1 - 4.4e-08 32.7 0.0 5.8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KFY05246.1 - 0.0077 16.3 0.0 0.087 12.9 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Tubulin_2 PF13809.1 KFY05246.1 - 0.015 14.2 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 Tubulin like Thioredoxin_2 PF13098.1 KFY05246.1 - 0.12 12.6 0.0 0.85 9.8 0.0 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain MFS_1 PF07690.11 KFY05247.1 - 7.2e-38 130.1 26.1 3.5e-28 98.3 6.6 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY05247.1 - 2.2e-12 46.3 13.6 2.2e-12 46.3 9.4 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter UPF0016 PF01169.14 KFY05248.1 - 1.6e-42 143.5 24.2 1.7e-21 76.1 5.0 2.5 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.11 KFY05248.1 - 0.0076 15.7 0.9 0.012 15.0 0.0 1.8 2 0 0 2 2 2 1 Integral membrane protein TerC family RRM_1 PF00076.17 KFY05253.1 - 6.2e-12 44.9 0.2 1.8e-05 24.2 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY05253.1 - 7.6e-11 41.8 0.2 0.00019 21.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KFY05253.1 - 1.7e-06 27.7 0.0 4.8e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PXA PF02194.10 KFY05254.1 - 5.5e-49 166.2 0.5 5.5e-49 166.2 0.3 2.8 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 KFY05254.1 - 7.8e-30 103.2 0.1 2.4e-29 101.7 0.1 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 KFY05254.1 - 2e-20 72.6 0.6 6.2e-20 71.0 0.4 1.9 1 0 0 1 1 1 1 PX domain RGS PF00615.14 KFY05254.1 - 2.8e-10 40.3 0.0 8.4e-10 38.7 0.0 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF2964 PF11177.3 KFY05254.1 - 0.087 12.7 3.1 0.21 11.5 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) Methyltransf_4 PF02390.12 KFY05255.1 - 5.9e-53 178.8 0.0 7.2e-53 178.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KFY05255.1 - 0.00014 22.4 0.0 0.00022 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY05255.1 - 0.00024 21.4 0.2 0.00082 19.6 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY05255.1 - 0.00051 20.4 0.0 0.001 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KFY05255.1 - 0.0011 18.3 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KFY05255.1 - 0.0015 18.5 0.0 0.0029 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KFY05255.1 - 0.0047 16.6 0.0 0.01 15.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain FmrO PF07091.6 KFY05255.1 - 0.0048 15.9 0.0 0.011 14.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_11 PF08241.7 KFY05255.1 - 0.0077 16.6 0.0 0.022 15.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY05255.1 - 0.025 14.1 0.0 0.034 13.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Homoserine_dh PF00742.14 KFY05257.1 - 1.2e-52 178.1 0.0 1.7e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 KFY05257.1 - 1.9e-18 66.9 0.0 3.1e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Bac_rhamnosid PF05592.6 KFY05265.1 - 1.9e-42 145.1 1.6 3e-35 121.4 1.6 2.4 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase F5_F8_type_C PF00754.20 KFY05265.1 - 2.2e-12 46.9 0.5 2.4e-11 43.5 0.2 2.4 2 0 0 2 2 2 1 F5/8 type C domain DUF608 PF04685.8 KFY05265.1 - 1.7e-10 40.1 1.1 2.8e-10 39.4 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 GDE_C PF06202.9 KFY05265.1 - 9.1e-06 24.6 0.1 1.5e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.13 KFY05265.1 - 0.00031 19.5 0.1 0.00046 18.9 0.1 1.1 1 0 0 1 1 1 1 Trehalase Glyco_hydro_63 PF03200.11 KFY05265.1 - 0.094 10.5 0.0 0.14 9.9 0.0 1.1 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase Glyco_hydro_11 PF00457.12 KFY05266.1 - 2e-82 274.9 17.9 2.4e-82 274.7 12.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 W_rich_C PF07483.6 KFY05266.1 - 0.86 9.3 5.6 0.38 10.4 0.8 2.2 2 1 0 2 2 2 0 Tryptophan-rich Synechocystis species C-terminal domain BA14K PF07886.6 KFY05266.1 - 5 6.8 5.6 31 4.3 0.4 2.8 2 0 0 2 2 2 0 BA14K-like protein Pectate_lyase_3 PF12708.2 KFY05268.1 - 2.3e-59 201.2 22.7 1.8e-52 178.7 4.2 3.6 3 1 0 3 3 3 2 Pectate lyase superfamily protein Peptidase_S8 PF00082.17 KFY05268.1 - 8e-19 67.8 0.2 8e-19 67.8 0.1 3.1 3 0 0 3 3 3 1 Subtilase family MA3 PF02847.12 KFY05268.1 - 1.1 8.9 0.0 2.2 7.9 0.0 1.4 1 0 0 1 1 1 0 MA3 domain 3-HAO PF06052.7 KFY05273.1 - 1.1e-08 34.6 0.1 1.1e-08 34.6 0.1 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Ctr PF04145.10 KFY05274.1 - 1e-07 32.0 0.0 1.5e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Ctr copper transporter family Sugar_tr PF00083.19 KFY05275.1 - 6.5e-62 209.5 22.2 2.6e-43 148.2 3.1 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFY05275.1 - 1.4e-05 23.9 48.8 3.2e-05 22.7 10.0 2.7 2 2 0 2 2 2 2 Major Facilitator Superfamily Methyltransf_6 PF03737.10 KFY05276.1 - 3.3e-28 98.4 0.4 4.2e-28 98.1 0.3 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase 2-Hacid_dh_C PF02826.14 KFY05277.1 - 5.1e-56 188.6 0.0 7e-56 188.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KFY05277.1 - 1.4e-26 92.5 0.0 1.7e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KFY05277.1 - 3.6e-06 26.9 0.1 6.9e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KFY05277.1 - 0.013 15.9 0.1 0.042 14.2 0.1 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 KFY05277.1 - 0.02 14.2 0.1 0.055 12.8 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain GFO_IDH_MocA PF01408.17 KFY05277.1 - 0.08 13.4 0.1 0.46 11.0 0.0 2.3 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Ldh_2 PF02615.9 KFY05278.1 - 2.3e-92 309.2 0.0 2.8e-92 309.0 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Gly_rich_SFCGS PF14272.1 KFY05278.1 - 0.082 12.7 0.4 0.17 11.7 0.3 1.4 1 0 0 1 1 1 0 Glycine-rich SFCGS MFS_1 PF07690.11 KFY05279.1 - 9.1e-27 93.6 24.5 1.2e-26 93.2 17.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily NfeD PF01957.13 KFY05279.1 - 4.9 7.2 9.2 13 5.9 0.0 4.0 4 2 2 6 6 6 0 NfeD-like C-terminal, partner-binding Amidohydro_2 PF04909.9 KFY05280.1 - 4.6e-22 78.8 0.1 5.9e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Glyco_trans_4_4 PF13579.1 KFY05280.1 - 0.029 14.5 0.1 0.082 13.0 0.0 1.7 1 1 1 2 2 2 0 Glycosyl transferase 4-like domain UBA_3 PF09288.5 KFY05280.1 - 0.036 13.6 0.0 0.081 12.5 0.0 1.7 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Fungal_trans PF04082.13 KFY05281.1 - 5.4e-24 84.4 0.6 9.8e-24 83.6 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY05281.1 - 2.1e-08 33.9 9.6 3.8e-08 33.0 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 KFY05284.1 - 5.8e-14 52.3 0.0 1e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KFY05284.1 - 9.9e-07 28.5 0.0 1.4e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 KR domain NACHT PF05729.7 KFY05284.1 - 0.016 14.8 0.0 0.032 13.8 0.0 1.4 1 1 0 1 1 1 0 NACHT domain adh_short_C2 PF13561.1 KFY05284.1 - 0.07 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_4 PF07993.7 KFY05284.1 - 0.14 11.0 0.0 0.28 10.0 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein PAN_1 PF00024.21 KFY05285.1 - 0.00036 20.2 3.5 0.1 12.3 0.2 3.5 3 0 0 3 3 3 2 PAN domain zf-C2H2_4 PF13894.1 KFY05287.1 - 8.4e-07 28.8 29.4 0.04 14.2 0.6 7.3 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2 PF00096.21 KFY05287.1 - 0.00019 21.6 20.0 0.1 12.9 0.5 6.0 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-met PF12874.2 KFY05287.1 - 0.021 15.0 5.4 0.099 12.8 0.3 4.0 5 0 0 5 5 5 0 Zinc-finger of C2H2 type lci PF12197.3 KFY05287.1 - 0.03 13.9 0.2 0.086 12.4 0.1 1.7 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein zf-Di19 PF05605.7 KFY05287.1 - 1 9.5 6.6 13 6.0 0.1 3.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 KFY05287.1 - 1.3 9.2 10.9 2.4 8.3 0.2 4.9 5 1 0 5 5 5 0 Zinc-finger double-stranded RNA-binding GLE1 PF07817.8 KFY05290.1 - 1.6e-24 86.2 0.0 2.3e-23 82.4 0.0 2.3 1 1 0 1 1 1 1 GLE1-like protein DUF3375 PF11855.3 KFY05290.1 - 0.5 9.0 9.0 1 8.0 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) TFIIA PF03153.8 KFY05290.1 - 5.7 6.7 13.1 8.6 6.1 9.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNB PF00773.14 KFY05291.1 - 7.9e-85 284.9 0.0 1.7e-84 283.9 0.0 1.6 1 0 0 1 1 1 1 RNB domain DUF4239 PF14023.1 KFY05291.1 - 0.33 10.2 0.1 0.71 9.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Ferritin_2 PF13668.1 KFY05292.1 - 1.7e-41 141.3 2.3 2.3e-41 140.9 1.6 1.2 1 0 0 1 1 1 1 Ferritin-like domain NAD_binding_10 PF13460.1 KFY05294.1 - 3.1e-06 27.3 0.0 3.7e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KFY05294.1 - 5.5e-05 22.2 0.1 0.0056 15.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 KFY05294.1 - 0.0057 15.5 0.0 0.014 14.3 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 KFY05294.1 - 0.014 15.7 0.0 0.025 14.8 0.0 1.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 KFY05294.1 - 0.034 13.5 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KFY05294.1 - 0.042 13.7 0.0 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase DapB_N PF01113.15 KFY05294.1 - 0.047 13.5 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 KFY05294.1 - 0.091 11.4 0.0 0.16 10.6 0.0 1.3 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KFY05296.1 - 3.7e-27 95.2 3.9 3.7e-27 95.2 2.7 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KFY05296.1 - 5.6e-22 78.6 0.1 8.5e-22 78.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KFY05296.1 - 2.6e-13 50.0 1.2 4.2e-13 49.3 0.8 1.3 1 0 0 1 1 1 1 KR domain N2227 PF07942.7 KFY05297.1 - 1.7e-97 325.6 0.0 2.2e-97 325.3 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 KFY05297.1 - 3.8e-05 23.4 0.0 0.00011 21.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain HEAT_EZ PF13513.1 KFY05298.1 - 1e-27 95.8 14.3 1.4e-14 54.0 0.0 10.9 9 2 3 12 12 12 5 HEAT-like repeat HEAT PF02985.17 KFY05298.1 - 1.9e-27 92.8 9.8 9.7e-06 25.2 0.0 9.6 10 0 0 10 10 10 5 HEAT repeat HEAT_2 PF13646.1 KFY05298.1 - 2.3e-23 82.2 0.2 3e-08 33.8 0.0 7.4 4 3 4 8 8 8 6 HEAT repeats Cnd1 PF12717.2 KFY05298.1 - 1.2e-11 44.8 0.8 0.029 14.2 0.0 6.1 5 1 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 KFY05298.1 - 4.2e-08 33.4 0.0 0.13 12.6 0.0 5.9 4 3 3 7 7 7 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 KFY05298.1 - 4.2e-07 29.5 0.0 0.11 11.8 0.0 6.5 6 1 0 7 7 7 1 CLASP N terminal MMS19_C PF12460.3 KFY05298.1 - 1.1e-06 27.6 1.3 0.3 9.7 0.0 4.7 4 1 0 5 5 5 2 RNAPII transcription regulator C-terminal IBN_N PF03810.14 KFY05298.1 - 1.3e-05 24.9 1.6 0.00025 20.9 0.1 4.0 4 1 0 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.18 KFY05298.1 - 1.9e-05 24.2 4.3 0.47 10.3 0.0 6.5 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 KFY05298.1 - 0.00037 18.9 0.0 1.7 6.9 0.1 4.0 2 2 2 4 4 4 1 Adaptin N terminal region RIX1 PF08167.7 KFY05298.1 - 0.3 10.7 2.9 9.5 5.8 0.0 4.2 4 1 1 5 5 5 0 rRNA processing/ribosome biogenesis HEAT_PBS PF03130.11 KFY05298.1 - 1.6 9.4 5.2 11 6.7 0.0 4.9 6 0 0 6 6 5 0 PBS lyase HEAT-like repeat RCC1 PF00415.13 KFY05299.1 - 9e-58 192.2 11.2 3.9e-09 36.5 0.0 8.0 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KFY05299.1 - 3.2e-34 115.8 32.5 8.1e-09 34.8 0.0 6.9 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat MIP-T3 PF10243.4 KFY05299.1 - 0.13 10.7 21.5 0.17 10.2 14.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Pam16 PF03656.8 KFY05300.1 - 4.5e-37 126.6 0.5 5.8e-37 126.3 0.4 1.1 1 0 0 1 1 1 1 Pam16 TctA PF01970.11 KFY05301.1 - 0.06 11.7 0.9 0.09 11.1 0.7 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family Peptidase_S49_N PF08496.5 KFY05301.1 - 3.3 7.4 16.1 2.1 8.0 6.9 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal RRM_1 PF00076.17 KFY05302.1 - 3.7e-09 36.0 0.1 6.9e-09 35.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KFY05302.1 - 1.3e-06 28.3 0.0 2.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Allexi_40kDa PF05549.6 KFY05302.1 - 0.024 13.9 0.4 0.037 13.3 0.3 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein CDC37_N PF03234.9 KFY05302.1 - 0.035 14.4 1.3 0.035 14.4 0.9 1.7 1 1 0 2 2 2 0 Cdc37 N terminal kinase binding Nup35_RRM_2 PF14605.1 KFY05302.1 - 0.046 13.4 0.0 0.097 12.4 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF3510 PF12022.3 KFY05302.1 - 0.056 13.5 2.9 2.6 8.1 2.0 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) RRM_3 PF08777.6 KFY05302.1 - 0.073 12.9 2.8 0.07 12.9 0.5 2.1 2 1 0 2 2 2 0 RNA binding motif MscS_porin PF12795.2 KFY05302.1 - 3 7.0 9.3 0.083 12.1 0.6 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Brix PF04427.13 KFY05306.1 - 9.7e-39 133.0 0.0 1.4e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain AMPKBI PF04739.10 KFY05306.1 - 0.32 10.8 1.4 8.5 6.3 1.0 2.5 1 1 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interation domain Glyco_hydro_2_C PF02836.12 KFY05307.1 - 6.2e-81 271.5 0.0 1.1e-80 270.7 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 KFY05307.1 - 1.7e-36 125.2 0.6 3e-36 124.4 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 KFY05307.1 - 2.4e-11 44.0 0.2 6.4e-11 42.6 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 DUF4434 PF14488.1 KFY05307.1 - 0.05 13.3 0.0 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) FAD_binding_4 PF01565.18 KFY05310.1 - 4e-17 61.9 0.0 6.6e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain zf-DNL PF05180.7 KFY05311.1 - 0.00067 19.3 0.1 0.0012 18.4 0.1 1.4 1 0 0 1 1 1 1 DNL zinc finger bZIP_2 PF07716.10 KFY05315.1 - 5.1e-05 23.0 25.1 0.00023 20.9 16.5 2.3 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.16 KFY05315.1 - 0.0012 18.7 19.6 0.0048 16.8 13.8 1.8 1 1 1 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 KFY05315.1 - 0.046 14.0 14.8 0.08 13.2 10.2 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor APG6 PF04111.7 KFY05315.1 - 0.73 8.8 5.3 0.97 8.4 3.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Ank_2 PF12796.2 KFY05320.1 - 1.8e-68 226.8 25.2 1.1e-16 60.9 0.0 7.5 2 2 7 9 9 9 8 Ankyrin repeats (3 copies) Ank PF00023.25 KFY05320.1 - 1.3e-58 192.0 35.0 6.2e-05 22.6 0.0 13.8 14 0 0 14 14 14 12 Ankyrin repeat Ank_4 PF13637.1 KFY05320.1 - 1.2e-49 165.8 15.5 3e-09 37.1 0.2 10.0 7 3 2 9 9 9 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY05320.1 - 4.1e-49 163.4 35.7 1.2e-09 38.1 0.0 12.9 4 2 9 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 KFY05320.1 - 3.6e-48 156.7 14.0 0.00091 19.2 0.0 13.6 14 0 0 14 14 14 11 Ankyrin repeat CHAP PF05257.11 KFY05320.1 - 0.28 10.8 0.5 35 4.0 0.0 3.5 3 1 1 4 4 4 0 CHAP domain Ank_2 PF12796.2 KFY05321.1 - 3.3e-88 290.1 8.6 1.2e-18 67.1 0.0 6.0 1 1 6 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 KFY05321.1 - 1.3e-66 217.2 16.1 5.7e-07 29.0 0.0 11.7 12 0 0 12 12 12 11 Ankyrin repeat Ank_3 PF13606.1 KFY05321.1 - 4.9e-59 190.3 3.6 3.9e-05 23.4 0.0 12.0 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.1 KFY05321.1 - 1.7e-55 184.4 6.6 1.6e-08 34.8 0.1 8.5 4 4 4 8 8 8 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY05321.1 - 5.4e-49 163.1 16.7 1.2e-08 34.9 0.0 10.2 1 1 9 10 10 10 9 Ankyrin repeats (many copies) F-box-like PF12937.2 KFY05321.1 - 2.6e-05 23.8 1.1 7.3e-05 22.4 0.1 2.3 3 0 0 3 3 3 1 F-box-like RVP PF00077.15 KFY05321.1 - 0.0074 16.1 0.4 2.7 7.9 0.0 3.5 1 1 2 3 3 3 1 Retroviral aspartyl protease Shigella_OspC PF06128.6 KFY05321.1 - 0.032 13.7 0.0 26 4.1 0.0 3.7 3 1 1 4 4 4 0 Shigella flexneri OspC protein Lipase_GDSL_2 PF13472.1 KFY05324.1 - 2.9e-16 60.0 0.8 2.9e-16 60.0 0.5 1.6 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KFY05324.1 - 1.3e-15 57.8 1.0 3.4e-15 56.5 0.7 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_43 PF04616.9 KFY05325.1 - 2.1e-46 158.2 6.8 2.4e-46 158.1 4.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Laminin_G_2 PF02210.19 KFY05326.1 - 0.00041 20.3 0.0 0.00086 19.3 0.0 1.5 1 0 0 1 1 1 1 Laminin G domain Laminin_G_1 PF00054.18 KFY05326.1 - 0.0012 18.8 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain MFS_1 PF07690.11 KFY05327.1 - 5.9e-36 123.9 46.0 3.8e-35 121.2 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DHDPS PF00701.17 KFY05328.1 - 5.8e-39 133.4 0.0 7.1e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Fungal_trans_2 PF11951.3 KFY05329.1 - 1.8e-18 66.3 0.0 2.4e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.16 KFY05330.1 - 1.7e-65 220.6 0.0 2.1e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aminotran_4 PF01063.14 KFY05331.1 - 1.4e-35 122.8 0.0 1.7e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV DUF2254 PF10011.4 KFY05331.1 - 0.095 11.1 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DAO PF01266.19 KFY05332.1 - 3.6e-25 88.6 0.0 4.9e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFY05332.1 - 0.00045 20.5 1.8 0.0014 18.9 1.2 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KFY05332.1 - 0.0016 18.5 0.1 0.0031 17.5 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFY05332.1 - 0.0036 17.2 0.3 0.019 14.8 0.2 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KFY05332.1 - 0.006 16.5 0.2 0.017 15.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_Gly3P_dh_N PF01210.18 KFY05332.1 - 0.037 13.7 0.2 1.9 8.2 0.1 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 KFY05332.1 - 0.054 12.5 0.7 0.59 9.1 0.1 2.1 2 0 0 2 2 2 0 Thi4 family K_oxygenase PF13434.1 KFY05332.1 - 0.083 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 KFY05332.1 - 0.087 11.8 0.4 0.15 11.1 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 KFY05332.1 - 0.1 12.3 0.1 0.18 11.5 0.1 1.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 KFY05332.1 - 0.14 11.5 0.5 0.24 10.7 0.4 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 KFY05332.1 - 2.6 7.8 4.2 1.6 8.5 0.7 2.1 2 0 0 2 2 2 0 ThiF family Fungal_trans_2 PF11951.3 KFY05333.1 - 1.8e-29 102.5 9.6 2.9e-29 101.8 6.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY05333.1 - 9.2e-05 22.2 3.4 0.00023 20.9 2.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trypan_PARP PF05887.6 KFY05334.1 - 0.3 10.8 4.7 0.62 9.8 3.3 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Herpes_LMP1 PF05297.6 KFY05334.1 - 3.5 6.4 7.9 5 5.9 5.5 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Paramecium_SA PF01508.11 KFY05334.1 - 6.4 7.0 14.4 0.25 11.5 1.7 2.8 2 1 0 2 2 2 0 Paramecium surface antigen domain F-box PF00646.28 KFY05335.1 - 0.0057 16.2 0.1 0.013 15.1 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KFY05335.1 - 0.097 12.4 0.1 0.097 12.4 0.1 1.8 2 0 0 2 2 2 0 F-box-like tRNA-synt_1c PF00749.16 KFY05336.1 - 1.5e-96 322.7 0.1 2.2e-96 322.2 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KFY05336.1 - 2.4e-37 128.2 0.3 4.7e-37 127.3 0.2 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.14 KFY05336.1 - 0.026 13.6 0.4 0.069 12.2 0.1 1.6 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain DSS1_SEM1 PF05160.8 KFY05336.1 - 0.65 9.8 7.4 0.21 11.3 2.0 2.4 2 0 0 2 2 2 0 DSS1/SEM1 family Zn_clus PF00172.13 KFY05337.1 - 8.8e-10 38.3 10.6 1.4e-09 37.7 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFY05337.1 - 3.2e-07 29.4 0.0 1e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Amino_oxidase PF01593.19 KFY05337.1 - 0.0043 16.1 0.4 0.0079 15.3 0.3 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Copper-fist PF00649.13 KFY05338.1 - 1.2e-19 69.1 1.2 1.2e-19 69.1 0.8 3.7 3 2 2 5 5 5 2 Copper fist DNA binding domain MFS_1 PF07690.11 KFY05339.1 - 1.8e-39 135.4 33.6 1.8e-39 135.4 23.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KFY05339.1 - 1.8e-06 26.8 15.1 1.8e-06 26.8 10.4 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KFY05341.1 - 1.5e-26 92.9 30.9 7.3e-25 87.4 19.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KFY05341.1 - 0.015 13.5 4.6 0.006 14.8 1.4 1.6 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) ATG13 PF10033.4 KFY05342.1 - 2.4e-67 226.7 0.0 1.8e-66 223.8 0.0 2.2 3 0 0 3 3 3 1 Autophagy-related protein 13 RCC1 PF00415.13 KFY05343.1 - 2.4e-19 69.2 0.5 0.00038 20.6 0.0 5.4 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 KFY05343.1 - 2.1e-10 40.5 0.0 6.1e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 KFY05343.1 - 4.2e-10 39.8 0.1 6.8e-05 23.2 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) RCC1_2 PF13540.1 KFY05343.1 - 4.8e-07 29.2 8.5 1.2e-06 27.9 3.3 3.0 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 KFY05343.1 - 6.4e-07 29.0 0.0 0.0076 16.3 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KFY05343.1 - 3.4e-06 27.3 0.0 6.4e-05 23.2 0.0 2.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KFY05343.1 - 1.6e-05 24.4 0.0 0.022 14.5 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KFY05343.1 - 1.6e-05 24.9 0.0 9.7e-05 22.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) RHD PF00554.17 KFY05343.1 - 0.1 12.3 0.4 0.73 9.5 0.0 2.6 3 0 0 3 3 3 0 Rel homology domain (RHD) Glyco_hydro_76 PF03663.9 KFY05344.1 - 1.5e-145 485.2 18.5 1.9e-145 484.8 12.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 KFY05344.1 - 0.0021 17.1 6.6 0.82 8.6 0.3 3.2 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 Glyco_hydro_30 PF02055.11 KFY05345.1 - 1.1e-28 99.7 0.3 1.5e-28 99.2 0.2 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 KFY05345.1 - 0.0027 16.7 0.0 0.0045 15.9 0.0 1.3 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 MIP PF00230.15 KFY05346.1 - 1.6e-28 99.7 9.5 2.7e-28 98.9 6.6 1.3 1 1 0 1 1 1 1 Major intrinsic protein ABC_tran PF00005.22 KFY05347.1 - 1e-47 161.8 0.1 5.2e-28 98.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KFY05347.1 - 7.7e-26 90.9 50.3 1.1e-20 74.0 9.0 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 KFY05347.1 - 2e-22 80.4 2.6 8.7e-07 29.1 0.0 4.6 4 1 0 5 5 4 4 AAA domain SMC_N PF02463.14 KFY05347.1 - 2.4e-07 30.2 2.0 4.9e-05 22.6 0.0 3.5 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KFY05347.1 - 4.7e-06 26.0 0.8 0.11 12.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KFY05347.1 - 1.7e-05 25.2 2.6 0.087 13.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 KFY05347.1 - 4.8e-05 22.5 0.0 0.2 10.6 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_19 PF13245.1 KFY05347.1 - 0.00011 21.9 3.4 0.088 12.5 0.0 3.1 3 0 0 3 3 3 2 Part of AAA domain AAA_30 PF13604.1 KFY05347.1 - 0.00014 21.5 0.2 0.061 12.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 KFY05347.1 - 0.00052 19.2 0.2 0.052 12.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane PF01061.19 KFY05347.1 - 0.00054 19.1 13.3 0.00054 19.1 9.2 3.8 4 0 0 4 4 2 2 ABC-2 type transporter RNA_helicase PF00910.17 KFY05347.1 - 0.0092 16.1 0.0 0.78 9.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA PF00004.24 KFY05347.1 - 0.0093 16.1 0.3 2.2 8.4 0.1 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFY05347.1 - 0.015 15.3 0.5 2.4 8.0 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KFY05347.1 - 0.028 14.5 0.6 4.7 7.3 0.1 3.0 2 2 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KFY05347.1 - 0.051 12.9 0.5 45 3.4 0.0 4.0 4 0 0 4 4 4 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 KFY05347.1 - 0.068 12.2 0.1 0.97 8.4 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.1 KFY05347.1 - 0.088 12.7 1.0 3.7 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KFY05347.1 - 0.14 11.5 1.7 3.7 6.8 0.3 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_25 PF13481.1 KFY05347.1 - 0.18 11.1 0.8 0.85 8.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.17 KFY05347.1 - 0.39 10.1 5.5 1.4 8.3 0.3 2.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain NACHT PF05729.7 KFY05347.1 - 0.46 10.1 1.4 26 4.4 0.2 2.5 2 0 0 2 2 2 0 NACHT domain DUF726 PF05277.7 KFY05348.1 - 1e-126 422.5 2.4 1.5e-126 421.9 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Pkinase PF00069.20 KFY05348.1 - 6.4e-16 58.2 0.7 3.9e-15 55.7 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KFY05348.1 - 6.4e-13 48.3 0.0 2.1e-12 46.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KFY05348.1 - 3.9e-05 22.7 0.0 7.6e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like UPF0565 PF10561.4 KFY05348.1 - 0.17 10.7 0.0 0.41 9.4 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 EamA PF00892.15 KFY05351.1 - 0.00017 21.6 12.8 0.00027 20.9 8.9 1.3 1 0 0 1 1 1 1 EamA-like transporter family EmrE PF13536.1 KFY05351.1 - 0.0039 17.3 4.4 0.0039 17.3 3.0 2.0 1 1 1 2 2 2 1 Multidrug resistance efflux transporter UPF0546 PF10639.4 KFY05351.1 - 0.036 13.8 2.0 0.052 13.3 1.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 Voltage_CLC PF00654.15 KFY05352.1 - 1.2e-88 297.5 25.9 1.2e-88 297.5 18.0 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KFY05352.1 - 8.6e-14 51.0 0.1 1.3e-06 28.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain CBFD_NFYB_HMF PF00808.18 KFY05354.1 - 6.4e-11 42.1 0.2 4.8e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Defensin_propep PF00879.13 KFY05354.1 - 0.11 12.4 2.4 0.23 11.4 1.7 1.6 1 0 0 1 1 1 0 Defensin propeptide DUF4611 PF15387.1 KFY05354.1 - 1.4 9.0 5.8 13 5.9 2.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) MoCF_biosynth PF00994.19 KFY05355.1 - 5.6e-56 187.9 0.2 2.4e-28 98.3 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 KFY05355.1 - 1.8e-32 111.9 1.0 2.8e-32 111.3 0.7 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 KFY05355.1 - 1.2e-15 57.1 0.8 3.7e-15 55.6 0.0 2.3 3 0 0 3 3 3 1 MoeA C-terminal region (domain IV) WD40 PF00400.27 KFY05355.1 - 8.1e-14 50.8 4.3 0.0019 18.0 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat YajC PF02699.10 KFY05355.1 - 1.1 8.9 4.5 5.5 6.7 0.4 3.2 3 0 0 3 3 3 0 Preprotein translocase subunit ATP_bind_1 PF03029.12 KFY05356.1 - 2e-72 243.6 0.0 2e-72 243.6 0.0 1.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 KFY05356.1 - 0.0014 17.4 0.0 0.003 16.3 0.0 1.5 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 KFY05356.1 - 0.0021 17.5 0.0 0.0043 16.4 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.1 KFY05356.1 - 0.0032 16.9 0.0 0.0065 15.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.1 KFY05356.1 - 0.028 13.9 0.3 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KFY05356.1 - 0.03 15.1 4.8 0.15 12.9 0.3 2.7 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KFY05356.1 - 0.038 13.4 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain RNase_P_Rpp14 PF01900.14 KFY05357.1 - 3.9e-37 126.4 0.0 5.6e-37 125.9 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Chitin_bind_1 PF00187.14 KFY05359.1 - 7.1e-06 25.9 21.0 1e-05 25.4 14.1 1.6 1 1 0 1 1 1 1 Chitin recognition protein Methyltransf_11 PF08241.7 KFY05361.1 - 6.3e-13 49.0 0.0 1.5e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KFY05361.1 - 7e-09 36.0 0.0 1.2e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KFY05361.1 - 8.1e-09 35.2 0.0 1.2e-08 34.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KFY05361.1 - 2.3e-08 34.3 0.0 3.6e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KFY05361.1 - 1e-06 29.2 0.0 1.6e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KFY05361.1 - 6.4e-06 25.9 0.0 8.5e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KFY05361.1 - 0.00041 19.5 0.0 0.0012 18.0 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 KFY05361.1 - 0.0085 15.5 0.0 0.0099 15.2 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.13 KFY05361.1 - 0.047 12.8 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Cupin_2 PF07883.6 KFY05362.1 - 8.4e-07 28.3 0.0 2.3e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 KFY05362.1 - 0.00055 19.2 0.0 0.00097 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) His_Phos_1 PF00300.17 KFY05363.1 - 7.6e-21 74.8 0.0 9.7e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 KFY05364.1 - 3.2e-24 85.9 0.0 7.9e-22 78.0 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) zf-CCHC_5 PF14787.1 KFY05364.1 - 0.13 11.7 0.1 0.32 10.4 0.1 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger PPR_2 PF13041.1 KFY05365.1 - 5.1e-27 93.6 0.0 2.2e-07 30.7 0.0 9.0 8 1 1 9 9 9 5 PPR repeat family PPR_3 PF13812.1 KFY05365.1 - 1.2e-15 56.3 2.9 0.0014 18.7 0.0 9.5 10 0 0 10 10 10 2 Pentatricopeptide repeat domain PPR PF01535.15 KFY05365.1 - 1.1e-14 53.2 0.4 0.005 16.7 0.1 7.1 8 0 0 8 8 8 3 PPR repeat PPR_1 PF12854.2 KFY05365.1 - 1e-13 50.4 0.3 0.017 14.6 0.0 8.3 9 0 0 9 9 9 3 PPR repeat ECSIT PF06239.6 KFY05365.1 - 0.0048 15.7 0.6 9.4 5.0 0.0 3.5 2 1 1 3 3 3 2 Evolutionarily conserved signalling intermediate in Toll pathway RPM2 PF08579.6 KFY05365.1 - 0.15 12.1 0.4 0.66 10.1 0.3 2.2 1 1 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) Vps39_2 PF10367.4 KFY05365.1 - 0.2 11.8 0.3 0.62 10.2 0.0 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Mis12 PF05859.7 KFY05366.1 - 3.3e-34 117.7 0.0 6.1e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein CHAP PF05257.11 KFY05367.1 - 0.0021 17.7 0.3 0.0073 15.9 0.0 2.0 2 0 0 2 2 2 1 CHAP domain Lactamase_B_2 PF12706.2 KFY05370.1 - 3.4e-34 118.1 0.1 8e-34 116.8 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 KFY05370.1 - 8.8e-26 89.1 0.1 2.8e-25 87.5 0.0 1.9 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 KFY05370.1 - 5.8e-05 22.8 0.0 0.00023 20.9 0.0 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily TCTP PF00838.12 KFY05371.1 - 1.7e-65 219.9 3.6 2e-65 219.8 2.5 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein S4 PF01479.20 KFY05371.1 - 0.008 15.5 0.1 0.24 10.8 0.1 2.4 1 1 1 2 2 2 1 S4 domain FA_hydroxylase PF04116.8 KFY05372.1 - 5.1e-17 62.3 10.1 5.1e-17 62.3 7.0 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Transport_MerF PF11431.3 KFY05372.1 - 0.26 10.9 3.5 0.82 9.3 0.6 2.5 2 0 0 2 2 2 0 Membrane transport protein MerF Mtc PF03820.12 KFY05374.1 - 2.3e-85 285.9 0.3 6.2e-85 284.5 0.2 1.5 1 1 0 1 1 1 1 Tricarboxylate carrier UEV PF05743.8 KFY05378.1 - 9.3e-38 128.6 0.0 1.3e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 UEV domain RNA_pol_Rpb2_6 PF00562.23 KFY05379.1 - 2.7e-123 411.5 0.1 1.2e-122 409.4 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KFY05379.1 - 5.6e-62 208.2 0.0 1e-61 207.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KFY05379.1 - 3.8e-49 166.6 0.0 7.6e-49 165.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 KFY05379.1 - 7.1e-25 86.5 0.3 2e-24 85.1 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 ADH_N PF08240.7 KFY05379.1 - 4.7e-24 84.2 4.5 1.6e-23 82.4 2.8 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain RNA_pol_Rpb2_3 PF04565.11 KFY05379.1 - 7.2e-23 80.1 0.0 1.5e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KFY05379.1 - 1e-20 73.4 0.1 2.4e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 ADH_zinc_N PF00107.21 KFY05379.1 - 2.7e-19 68.9 0.0 7.7e-19 67.5 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KFY05379.1 - 9.7e-09 36.1 0.0 2.4e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RNA_pol_Rpb2_7 PF04560.15 KFY05379.1 - 0.0064 16.7 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 2-Hacid_dh_C PF02826.14 KFY05379.1 - 0.016 14.3 0.1 0.032 13.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4241 PF14025.1 KFY05379.1 - 0.15 11.8 0.5 1.4 8.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4241) FWWh PF14922.1 KFY05379.1 - 0.26 10.7 0.1 0.55 9.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF3539 PF12058.3 KFY05380.1 - 0.11 12.3 0.2 0.14 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3539) V-ATPase_G PF03179.10 KFY05381.1 - 2.9e-33 114.2 15.4 3.3e-33 114.1 10.7 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 KFY05381.1 - 0.0034 17.1 8.6 0.0034 17.1 6.0 2.1 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) Nop25 PF09805.4 KFY05381.1 - 0.071 13.1 14.9 0.088 12.8 10.3 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) RE_AlwI PF09491.5 KFY05381.1 - 0.092 11.1 4.5 0.11 10.9 3.1 1.1 1 0 0 1 1 1 0 AlwI restriction endonuclease DUF3552 PF12072.3 KFY05381.1 - 0.15 11.2 19.7 0.03 13.5 8.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) AAA_13 PF13166.1 KFY05381.1 - 0.34 9.3 9.5 0.37 9.1 6.6 1.0 1 0 0 1 1 1 0 AAA domain RP-C_C PF11800.3 KFY05381.1 - 0.51 10.0 5.3 0.59 9.7 3.7 1.0 1 0 0 1 1 1 0 Replication protein C C-terminal region HrpE PF06188.7 KFY05381.1 - 0.83 9.3 8.7 1 9.1 2.0 2.0 1 1 1 2 2 2 0 HrpE/YscL/FliH and V-type ATPase subunit E DUF1423 PF07227.6 KFY05381.1 - 0.99 7.9 9.5 1.1 7.8 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) RRF PF01765.14 KFY05381.1 - 1 8.8 14.3 1.5 8.2 9.3 1.7 1 1 1 2 2 2 0 Ribosome recycling factor Colicin-DNase PF12639.2 KFY05381.1 - 1.9 8.8 6.9 1.9 8.8 3.1 1.8 1 1 1 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin Vfa1 PF08432.5 KFY05381.1 - 2.5 8.0 12.2 3 7.8 8.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 APG6 PF04111.7 KFY05381.1 - 2.9 6.8 8.4 3.3 6.6 5.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Borrelia_P83 PF05262.6 KFY05381.1 - 4 5.5 13.3 4.2 5.5 9.2 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein vATP-synt_E PF01991.13 KFY05381.1 - 4.6 6.4 19.4 0.49 9.6 6.1 2.1 1 1 0 2 2 2 0 ATP synthase (E/31 kDa) subunit SAPS PF04499.10 KFY05381.1 - 8 4.9 8.0 8.2 4.9 5.5 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF883 PF05957.8 KFY05381.1 - 8.6 6.8 10.5 15 6.0 4.1 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) PGAP1 PF07819.8 KFY05382.1 - 1.7e-06 27.7 0.0 2.9e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KFY05382.1 - 5.4e-06 25.8 0.0 9.8e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KFY05382.1 - 8.3e-06 25.8 0.0 1.3e-05 25.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 KFY05382.1 - 0.00021 20.4 0.0 0.00038 19.5 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 KFY05382.1 - 0.01 15.1 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 KFY05382.1 - 0.011 15.5 0.0 0.021 14.5 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_2 PF01674.13 KFY05382.1 - 0.045 13.0 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 2) Abhydrolase_1 PF00561.15 KFY05382.1 - 0.051 13.1 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Arrestin_N PF00339.24 KFY05383.1 - 2.1e-15 56.8 0.2 3.5e-09 36.6 0.0 2.6 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain p47_phox_C PF08944.6 KFY05383.1 - 0.032 14.4 0.2 0.087 13.0 0.1 1.7 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain SHS2_Rpb7-N PF03876.12 KFY05385.1 - 3e-07 30.4 0.0 5.4e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 MIP-T3 PF10243.4 KFY05385.1 - 0.079 11.4 20.6 0.13 10.7 14.3 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Usp PF00582.21 KFY05385.1 - 2.1 8.5 7.1 1.4 9.1 3.3 1.8 1 1 1 2 2 2 0 Universal stress protein family DUF123 PF01986.11 KFY05388.1 - 0.01 15.9 0.1 0.07 13.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF123 Sel1 PF08238.7 KFY05391.1 - 1.8e-13 50.6 21.9 7.2e-07 29.6 0.1 7.5 7 0 0 7 7 7 6 Sel1 repeat TBPIP PF07106.8 KFY05392.1 - 1.6e-30 105.8 0.1 2e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 KFY05392.1 - 0.0013 18.3 0.4 0.0025 17.5 0.3 1.5 1 1 0 1 1 1 1 Mnd1 family EAP30 PF04157.11 KFY05392.1 - 0.01 14.9 0.8 0.032 13.3 0.0 1.9 2 0 0 2 2 2 0 EAP30/Vps36 family SHOCT PF09851.4 KFY05392.1 - 0.05 13.0 3.0 4.8 6.7 0.1 3.1 3 0 0 3 3 3 0 Short C-terminal domain IncA PF04156.9 KFY05392.1 - 0.079 12.5 0.7 0.13 11.8 0.5 1.4 1 1 0 1 1 1 0 IncA protein DUF4600 PF15372.1 KFY05392.1 - 0.37 11.0 4.0 3.3 7.9 2.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Cortex-I_coil PF09304.5 KFY05392.1 - 1.9 8.5 6.6 1.2 9.2 3.2 1.8 2 1 0 2 2 2 0 Cortexillin I, coiled coil PMI_typeI PF01238.16 KFY05395.1 - 2.2e-49 168.3 0.2 8.3e-45 153.3 0.1 3.0 1 1 1 2 2 2 2 Phosphomannose isomerase type I AraC_N PF06719.8 KFY05395.1 - 0.13 11.5 0.0 0.37 10.0 0.0 1.7 1 0 0 1 1 1 0 AraC-type transcriptional regulator N-terminus GFA PF04828.9 KFY05396.1 - 1.4e-18 66.6 0.3 1.9e-18 66.1 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Ank_2 PF12796.2 KFY05398.1 - 2.5e-216 700.8 5.5 6.9e-24 84.0 0.0 9.7 1 1 11 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.25 KFY05398.1 - 6.5e-152 486.4 0.0 8.3e-09 34.8 0.0 18.6 19 0 0 19 19 19 17 Ankyrin repeat Ank_3 PF13606.1 KFY05398.1 - 1.6e-121 383.8 0.0 3.1e-06 26.8 0.0 18.1 18 0 0 18 18 18 17 Ankyrin repeat Ank_4 PF13637.1 KFY05398.1 - 2.3e-117 381.5 0.2 4.7e-11 42.8 0.0 14.9 4 3 13 17 17 17 16 Ankyrin repeats (many copies) Ank_5 PF13857.1 KFY05398.1 - 2.3e-88 288.2 7.9 4.3e-08 33.1 0.0 16.6 2 1 16 18 18 18 17 Ankyrin repeats (many copies) PEGA PF08308.6 KFY05398.1 - 9.7e-07 28.4 0.2 12 5.7 0.0 9.6 11 1 1 12 12 12 1 PEGA domain UDPG_MGDP_dh_C PF03720.10 KFY05398.1 - 4.4e-06 26.8 14.7 51 4.0 0.0 11.8 7 5 2 9 9 9 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain HEM4 PF02602.10 KFY05398.1 - 6e-05 22.3 2.4 0.14 11.4 0.0 4.7 4 2 2 6 6 6 2 Uroporphyrinogen-III synthase HemD DUF4350 PF14258.1 KFY05398.1 - 0.0003 20.9 6.7 31 4.8 0.0 8.8 7 3 2 10 10 10 0 Domain of unknown function (DUF4350) Amidinotransf PF02274.12 KFY05398.1 - 0.012 14.6 15.8 27 3.7 0.0 8.9 2 2 4 7 7 7 0 Amidinotransferase HMG_box PF00505.14 KFY05402.1 - 2e-13 50.4 0.0 5.2e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box CP2 PF04516.10 KFY05402.1 - 9.9e-11 41.1 0.1 2.4e-10 39.8 0.1 1.6 2 0 0 2 2 2 1 CP2 transcription factor SAM_1 PF00536.25 KFY05402.1 - 5e-10 39.4 0.0 1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.5 KFY05402.1 - 7.3e-10 39.0 0.0 2e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 HMG-box domain SAM_2 PF07647.12 KFY05402.1 - 3.5e-08 33.1 0.3 1.4e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) NCD1 PF04904.8 KFY05402.1 - 0.16 11.7 0.0 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 NAB conserved region 1 (NCD1) Ecl1 PF12855.2 KFY05403.1 - 9.1e-10 37.6 1.5 1.3e-09 37.2 1.0 1.2 1 0 0 1 1 1 1 Life-span regulatory factor DUF329 PF03884.9 KFY05403.1 - 0.0024 17.4 2.0 0.004 16.6 1.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF329) DUF581 PF04570.9 KFY05403.1 - 0.029 13.6 5.1 0.13 11.5 3.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF581) zf-FCS PF06467.9 KFY05403.1 - 0.088 12.4 2.5 0.26 10.9 1.5 1.9 2 1 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif C1_1 PF00130.17 KFY05403.1 - 0.62 9.8 4.3 2 8.2 3.2 1.6 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_clus PF00172.13 KFY05406.1 - 1.2e-07 31.5 9.5 2.4e-07 30.5 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KFY05406.1 - 1.4e-07 30.6 0.4 4.2e-07 29.0 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 KFY05407.1 - 1.3e-08 34.0 0.4 2.1e-08 33.3 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY05407.1 - 3.8e-05 23.4 10.3 3.8e-05 23.4 7.2 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mob_synth_C PF06463.8 KFY05407.1 - 0.087 12.5 1.7 0.2 11.3 1.2 1.6 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C HMG_box PF00505.14 KFY05408.1 - 1.1e-13 51.1 1.0 2.4e-13 50.1 0.7 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KFY05408.1 - 3.4e-13 49.7 1.3 6.9e-13 48.7 0.9 1.5 1 0 0 1 1 1 1 HMG-box domain Fungal_trans PF04082.13 KFY05408.1 - 2.4e-12 46.2 0.1 4.8e-12 45.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain SAM_1 PF00536.25 KFY05408.1 - 9e-11 41.7 0.1 2e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 KFY05408.1 - 8.7e-08 31.8 0.0 1.8e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ins_allergen_rp PF06757.8 KFY05408.1 - 0.26 10.7 2.8 0.43 10.0 1.1 2.0 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification DsbD_2 PF13386.1 KFY05412.1 - 0.00084 19.1 0.7 0.00084 19.1 0.5 1.4 2 0 0 2 2 2 1 Cytochrome C biogenesis protein transmembrane region AA_permease_2 PF13520.1 KFY05412.1 - 0.0012 17.4 1.4 0.0015 17.1 1.0 1.0 1 0 0 1 1 1 1 Amino acid permease Neur_chan_memb PF02932.11 KFY05412.1 - 0.14 12.0 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Vma12 PF11712.3 KFY05412.1 - 0.36 10.5 4.6 0.23 11.1 0.1 2.0 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1673 PF07895.6 KFY05412.1 - 2.4 7.6 7.1 6.4 6.2 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) FAD_binding_3 PF01494.14 KFY05414.1 - 4.5e-20 72.0 0.5 6e-19 68.2 0.4 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KFY05414.1 - 9.5e-09 34.5 0.3 1.6e-08 33.8 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KFY05414.1 - 1.1e-07 31.7 0.1 2.7e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KFY05414.1 - 2e-07 30.2 1.1 6.9e-07 28.4 0.1 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFY05414.1 - 7.3e-06 26.3 0.7 5.7e-05 23.4 0.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFY05414.1 - 1e-05 25.4 0.2 2.8e-05 24.0 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KFY05414.1 - 9.9e-05 21.3 0.1 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 KFY05414.1 - 0.00012 21.7 0.0 0.00024 20.7 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 KFY05414.1 - 0.00013 20.5 0.2 0.00021 19.8 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.19 KFY05414.1 - 0.00017 20.7 0.1 0.0011 18.1 0.1 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase ApbA PF02558.11 KFY05414.1 - 0.00046 19.6 0.0 0.0059 16.0 0.0 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 KFY05414.1 - 0.00054 20.0 0.0 0.0009 19.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KFY05414.1 - 0.00099 18.2 0.1 0.0017 17.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_10 PF13460.1 KFY05414.1 - 0.0041 17.1 0.2 0.037 14.0 0.1 2.3 2 0 0 2 2 2 1 NADH(P)-binding UDPG_MGDP_dh_N PF03721.9 KFY05414.1 - 0.0042 16.4 0.0 0.0083 15.5 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 KFY05414.1 - 0.0061 16.2 0.2 0.013 15.1 0.2 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 KFY05414.1 - 0.0067 15.1 0.3 0.046 12.3 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.2 KFY05414.1 - 0.0094 15.0 0.1 0.015 14.3 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.13 KFY05414.1 - 0.013 15.4 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.7 KFY05414.1 - 0.016 14.1 0.2 0.065 12.1 0.0 2.0 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 KFY05414.1 - 0.029 14.6 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding p450 PF00067.17 KFY05415.1 - 3.6e-50 170.8 0.0 4.6e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_3 PF13738.1 KFY05416.1 - 5.3e-25 88.6 0.0 9.2e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KFY05416.1 - 6.2e-13 47.7 0.0 1.2e-11 43.5 0.0 2.3 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 KFY05416.1 - 1.7e-09 37.5 0.0 1.5e-08 34.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KFY05416.1 - 7.3e-07 28.5 0.0 2.1e-05 23.7 0.0 2.5 3 0 0 3 3 3 1 Thi4 family K_oxygenase PF13434.1 KFY05416.1 - 5.5e-05 22.2 0.0 0.0067 15.3 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KFY05416.1 - 0.00024 20.1 0.7 0.00091 18.2 0.1 2.2 3 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KFY05416.1 - 0.00093 19.5 0.1 0.21 12.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KFY05416.1 - 0.0011 18.9 0.0 0.0061 16.4 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KFY05416.1 - 0.0052 15.7 0.5 0.021 13.7 0.0 2.2 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KFY05416.1 - 0.0074 16.0 0.7 1.9 8.2 0.0 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding GIDA PF01134.17 KFY05416.1 - 0.013 14.4 0.7 0.43 9.3 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KFY05416.1 - 0.028 13.2 0.0 0.052 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KFY05416.1 - 0.17 10.3 0.3 0.35 9.2 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein efThoc1 PF11957.3 KFY05417.1 - 1e-162 542.1 0.1 1.6e-162 541.4 0.1 1.3 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.16 KFY05417.1 - 7.1e-48 162.4 0.0 1.2e-47 161.7 0.0 1.3 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 KFY05417.1 - 5.7e-06 26.6 0.0 2.1e-05 24.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KFY05417.1 - 0.013 15.3 0.3 1.3 8.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KFY05417.1 - 0.017 14.3 0.0 0.047 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF313 PF03754.8 KFY05417.1 - 0.096 12.6 0.2 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF313) AAA_12 PF13087.1 KFY05418.1 - 9.5e-27 93.6 0.0 1.8e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KFY05418.1 - 1.6e-24 86.7 0.0 4.6e-24 85.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KFY05418.1 - 3.7e-10 39.3 0.1 1.1e-08 34.6 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KFY05418.1 - 2.9e-06 27.0 0.0 0.0045 16.6 0.0 2.7 3 0 0 3 3 2 2 AAA domain Viral_helicase1 PF01443.13 KFY05418.1 - 0.00014 21.4 0.6 0.0069 15.9 0.0 3.1 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 KFY05418.1 - 0.00055 19.4 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 KFY05418.1 - 0.00069 19.4 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KFY05418.1 - 0.0022 18.1 0.0 0.0081 16.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KFY05418.1 - 0.0024 18.0 0.0 0.006 16.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KFY05418.1 - 0.011 15.7 0.0 0.048 13.6 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain DnaB_C PF03796.10 KFY05418.1 - 0.019 13.8 0.0 0.036 12.9 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain DEAD PF00270.24 KFY05418.1 - 0.019 14.4 0.0 0.061 12.8 0.0 1.8 2 0 0 2 2 1 0 DEAD/DEAH box helicase DUF2075 PF09848.4 KFY05418.1 - 0.02 13.8 0.8 0.031 13.2 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UvrD_C_2 PF13538.1 KFY05418.1 - 0.023 14.8 0.0 0.063 13.4 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_17 PF13207.1 KFY05418.1 - 0.031 15.1 0.0 0.32 11.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KFY05418.1 - 0.055 12.3 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 KFY05418.1 - 0.072 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_5 PF07728.9 KFY05418.1 - 0.085 12.5 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 KFY05418.1 - 0.11 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 KFY05418.1 - 0.26 11.4 0.0 0.7 10.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase MIF4G PF02854.14 KFY05419.1 - 1.8e-50 171.3 0.0 2.8e-50 170.6 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 KFY05419.1 - 1.4e-22 79.3 1.2 5.6e-22 77.4 0.8 2.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 ABC2_membrane PF01061.19 KFY05420.1 - 5e-87 290.4 50.1 1.8e-48 164.4 13.5 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 KFY05420.1 - 1.8e-34 118.9 0.1 9.7e-17 61.5 0.0 3.3 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 KFY05420.1 - 4.8e-28 96.8 0.6 3.9e-25 87.4 0.0 3.1 2 0 0 2 2 2 1 CDR ABC transporter ABC2_membrane_3 PF12698.2 KFY05420.1 - 7e-10 38.4 40.8 9.4e-08 31.4 12.7 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 KFY05420.1 - 6.8e-06 25.6 0.2 0.0018 17.6 0.1 2.7 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 KFY05420.1 - 3.2e-05 24.0 0.1 0.071 13.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain cobW PF02492.14 KFY05420.1 - 7.9e-05 22.1 0.0 0.0091 15.4 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KFY05420.1 - 9.8e-05 21.5 0.0 0.00065 18.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 KFY05420.1 - 0.00054 20.4 0.4 3.7 8.0 0.0 3.6 3 0 0 3 3 3 1 Miro-like protein AAA_33 PF13671.1 KFY05420.1 - 0.00055 19.8 0.0 0.7 9.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KFY05420.1 - 0.00056 19.9 0.1 0.058 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 KFY05420.1 - 0.0022 17.7 0.0 0.22 11.1 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase ABC_trans_N PF14510.1 KFY05420.1 - 0.0054 16.7 0.0 0.015 15.3 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_29 PF13555.1 KFY05420.1 - 0.0067 15.9 2.9 0.066 12.7 0.2 3.1 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA PF00004.24 KFY05420.1 - 0.0069 16.5 0.0 2.1 8.5 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 KFY05420.1 - 0.012 15.0 0.1 0.42 10.0 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family UPF0079 PF02367.12 KFY05420.1 - 0.019 14.6 1.4 3.4 7.3 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 KFY05420.1 - 0.027 14.1 0.3 4.6 6.8 0.2 2.5 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.1 KFY05420.1 - 0.035 14.0 0.0 2.6 7.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 KFY05420.1 - 0.049 13.9 0.0 1 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KFY05420.1 - 0.05 13.5 0.2 0.18 11.7 0.1 2.0 2 0 0 2 2 1 0 AAA domain Fungal_trans PF04082.13 KFY05421.1 - 1.5e-14 53.5 0.3 2.6e-14 52.7 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KFY05421.1 - 6.3e-07 29.2 9.7 1.4e-06 28.0 6.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain